doc_id	sent_index	relation_id	relation	trigger	trigger_offset	arg_num	arg_head	arg_protein	arg_domain	arg_site	arg_sugar	arg_head_offset	arg_base_np	arg_base_np_offset	arg_np	arg_np_offset	sent_text	PSource	NProtein	NID	SiteSource	SiteName
36892032	7	0	theme	Eudragit	1520:1527	arg1	polymers					1490:1497	two polymers	1486:1497	two polymers (Sodium alginate and Eudragit RL100)	1486:1534	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	0	theme	Eudragit	1520:1527	arg1	RL100					1529:1533	Eudragit RL100	1520:1533	Eudragit RL100	1520:1533	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	4	1	theme	SEM	963:965	arg1	interpretation					940:953	The interpretation	936:953	The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads	936:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	8	2	theme	drug	1714:1717	arg1	systems					1728:1734	optimal drug delivery systems	1706:1734	optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1706:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	2	3	theme	Drug	667:670	arg1	Efficiency					683:692	Drug Entrapment Efficiency	667:692	Drug Entrapment Efficiency	667:692	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	1	4	theme	complextation	291:303	arg1	Objective					305:313	polymer complextation Objective	283:313	polymer complextation Objective	283:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	6	5	theme	particle	1318:1325	arg1	size					1327:1330	the particle size	1314:1330	the particle size	1314:1330	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	1	6	theme	Central	513:519	arg1	design					531:536	Central composite design	513:536	Central composite design	513:536	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	8	7	theme	Vildagliptin	1739:1750	arg1	microbeads					1776:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	2	8	theme	X-ray	695:699	arg1	diffraction					701:711	X-ray diffraction	695:711	X-ray diffraction	695:711	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	6	9	theme	composite	1228:1236	arg1	design					1238:1243	The 32 central composite design	1213:1243	The 32 central composite design	1213:1243	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	1	10	theme	Eudragit	459:466	arg1	RL100					468:472	Eudragit RL100	459:472	Eudragit RL100	459:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	8	11	theme	complex	1768:1774	arg1	microbeads					1776:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	2	12	theme	Scanning	630:637	arg1	Calorimetry					639:649	Differential Scanning Calorimetry	617:649	Differential Scanning Calorimetry	617:649	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	3	13	theme	variables	823:831	arg1	impact					801:806	The impact	797:806	The impact of independent variables like concentration of sodium alginate and eudragit RL100	797:888	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	1	14	theme	entrapment	215:224	arg1	efficiency					226:235	drug entrapment efficiency	210:235	drug entrapment efficiency	210:235	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	6	15	dep	used	1257:1260	arg1	obtain					1265:1270	obtain	1265:1270	was further used to obtain response surface graph	1245:1293	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	3	16	theme	sodium	855:860	arg1	alginate					862:869	sodium alginate	855:869	sodium alginate	855:869	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	5	17	theme	drug	1134:1137	arg1	release					1139:1145	the maximum and minimum drug release	1110:1145	the maximum and minimum drug release after 10 hours	1110:1160	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	17	theme	drug	1134:1137	arg1	%					1196:1196	89.45%	1191:1196	89.45%	1191:1196	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	17	theme	drug	1134:1137	arg1	%					1185:1185	96.23.5%	1178:1185	96.23.5%	1178:1185	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	7	18	dep	suggested	1457:1465	arg1	suitable					1541:1548	suitable	1541:1548	suitable	1541:1548	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	6	19	theme	surface	1281:1287	arg1	graph					1289:1293	response surface graph	1272:1293	response surface graph	1272:1293	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	4	20	theme	complex	1066:1072	arg1	microbeads					1074:1083	polyelectrolyte complex microbeads	1050:1083	polyelectrolyte complex microbeads	1050:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	4	21	theme	drug	994:997	arg1	interference					1010:1021	no drug excipients interference	991:1021	no drug excipients interference	991:1021	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	3	22	theme	RL100	884:888	arg1	concentration					838:850	concentration	838:850	concentration of sodium alginate and eudragit RL100	838:888	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	0	23	theme	Microbeads	69:78	arg1	Design					0:5	Design	0:5	Design	0:5	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	0	23	theme	Microbeads	69:78	arg1	Optimization					23:34	Statistical Optimization	11:34	Statistical Optimization	11:34	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	1	24	theme	current	163:169	arg1	research					171:178	The current research	159:178	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.	148:537	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	7	25	theme	drug	1605:1608	arg1	efficiency					1579:1588	the entrapment efficiency	1564:1588	the entrapment efficiency of hydrophilic drug (Vildagliptin)	1564:1623	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	2	26	theme	Electron	596:603	arg1	Microscope					605:614	Scanning Electron Microscope	587:614	Scanning Electron Microscope	587:614	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	3	27	theme	dependent	908:916	arg1	responses					918:926	dependent responses	908:926	dependent responses	908:926	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	1	28	theme	complex	398:404	arg1	microbeads					406:415	Polyelectrolyte complex microbeads	382:415	Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100	382:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	2	29	theme	in-vitro	717:724	arg1	release					731:737	in-vitro drug release	717:737	in-vitro drug release	717:737	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	0	30	theme	Release	117:123	arg1	Study					125:129	Release Study	117:129	Release Study	117:129	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	2	31	theme	Infrared	564:571	arg1	Spectroscopy					573:584	Infrared Spectroscopy	564:584	Infrared Spectroscopy	564:584	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	0	32	theme	Statistical	11:21	arg1	Optimization					23:34	Statistical Optimization	11:34	Statistical Optimization	11:34	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	1	33	theme	Ionotropic	316:325	arg1	technique					336:344	Ionotropic gelation technique	316:344	Ionotropic gelation technique	316:344	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	5	34	theme	maximum	1114:1120	arg1	release					1139:1145	the maximum and minimum drug release	1110:1145	the maximum and minimum drug release after 10 hours	1110:1160	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	34	theme	maximum	1114:1120	arg1	%					1196:1196	89.45%	1191:1196	89.45%	1191:1196	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	34	theme	maximum	1114:1120	arg1	%					1185:1185	96.23.5%	1178:1185	96.23.5%	1178:1185	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	4	35	theme	DSC	968:970	arg1	interpretation					940:953	The interpretation	936:953	The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads	936:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	0	36	theme	Polyelectrolyte	45:59	arg1	Microbeads					69:78	Novel Polyelectrolyte Complex Microbeads	39:78	Novel Polyelectrolyte Complex Microbeads	39:78	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	7	37	dep	polymers	1490:1497	arg1	polymers					1490:1497	two polymers	1486:1497	two polymers (Sodium alginate and Eudragit RL100)	1486:1534	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	37	dep	polymers	1490:1497	arg1	alginate					1507:1514	Sodium alginate	1500:1514	Sodium alginate	1500:1514	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	37	dep	polymers	1490:1497	arg1	RL100					1529:1533	Eudragit RL100	1520:1533	Eudragit RL100	1520:1533	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	5	38	theme	minimum	1126:1132	arg1	release					1139:1145	the maximum and minimum drug release	1110:1145	the maximum and minimum drug release after 10 hours	1110:1160	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	38	theme	minimum	1126:1132	arg1	%					1196:1196	89.45%	1191:1196	89.45%	1191:1196	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	5	38	theme	minimum	1126:1132	arg1	%					1185:1185	96.23.5%	1178:1185	96.23.5%	1178:1185	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	1	39	theme	release	241:247	arg1	study					249:253	drug entrapment efficiency and release study	210:253	drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective	210:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	5	40	theme	complex	1090:1096	arg1	microbeads					1098:1107	complex microbeads	1090:1107	complex microbeads	1090:1107	For complex microbeads, the maximum and minimum drug release after 10 hours was obtained as 96.23.5% and 89.45%, respectively.					
36892032	8	41	theme	effective	1677:1685	arg1	tool					1687:1690	an effective tool	1674:1690	an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1674:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	8	41	theme	effective	1677:1685	arg1	technique					1661:1669	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	8	42	theme	composite	1638:1646	arg1	CCD					1656:1658	CCD	1656:1658	CCD	1656:1658	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	8	42	theme	composite	1638:1646	arg1	design					1648:1653	central composite design	1630:1653	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	6	43	theme	Drug	1341:1344	arg1	release					1346:1352	Drug release	1341:1352	Drug release	1341:1352	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	1	44	theme	drug	270:273	arg1	study					249:253	drug entrapment efficiency and release study	210:253	drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective	210:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	7	45	theme	Sodium	1500:1505	arg1	polymers					1490:1497	two polymers	1486:1497	two polymers (Sodium alginate and Eudragit RL100)	1486:1534	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	45	theme	Sodium	1500:1505	arg1	alginate					1507:1514	Sodium alginate	1500:1514	Sodium alginate	1500:1514	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	2	46	theme	Entrapment	672:681	arg1	Efficiency					683:692	Drug Entrapment Efficiency	667:692	Drug Entrapment Efficiency	667:692	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	8	47	theme	optimal	1706:1712	arg1	systems					1728:1734	optimal drug delivery systems	1706:1734	optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1706:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	1	48	theme	polymer	283:289	arg1	Objective					305:313	polymer complextation Objective	283:313	polymer complextation Objective	283:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	7	49	theme	polymers	1490:1497	arg1	combination					1471:1481	the combination	1467:1481	the combination of two polymers (Sodium alginate and Eudragit RL100)	1467:1534	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	3	50	theme	independent	811:821	arg1	variables					823:831	independent variables	811:831	independent variables like concentration of sodium alginate and eudragit RL100	811:888	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	8	51	theme	delivery	1719:1726	arg1	systems					1728:1734	optimal drug delivery systems	1706:1734	optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1706:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	4	52	theme	microbeads	1074:1083	arg1	formation					1037:1045	formation	1037:1045	formation of polyelectrolyte complex microbeads	1037:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	1	53	theme	composite	521:529	arg1	design					531:536	Central composite design	513:536	Central composite design	513:536	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	6	54	theme	central	1220:1226	arg1	design					1238:1243	The 32 central composite design	1213:1243	The 32 central composite design	1213:1243	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	0	55	theme	Vildagliptin	134:145	arg1	Efficiency					102:111	Entrapment Efficiency	91:111	Entrapment Efficiency	91:111	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	0	55	theme	Vildagliptin	134:145	arg1	Study					125:129	Release Study	117:129	Release Study	117:129	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	8	56	theme	polyelectrolyte	1752:1766	arg1	microbeads					1776:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	Vildagliptin polyelectrolyte complex microbeads	1739:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	1	57	theme	drug	210:213	arg1	efficiency					226:235	drug entrapment efficiency	210:235	drug entrapment efficiency	210:235	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	4	58	theme	XRD	958:960	arg1	interpretation					940:953	The interpretation	936:953	The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads	936:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	2	59	theme	Differential	617:628	arg1	Calorimetry					639:649	Differential Scanning Calorimetry	617:649	Differential Scanning Calorimetry	617:649	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	1	60	theme	Sodium	439:444	arg1	alginate					446:453	Sodium alginate	439:453	Sodium alginate	439:453	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	6	61	used	used	1257:1260	arg2	design					1238:1243	The 32 central composite design	1213:1243	The 32 central composite design	1213:1243	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	1	62	theme	efficiency	226:235	arg1	study					249:253	drug entrapment efficiency and release study	210:253	drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective	210:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	4	63	theme	excipients	999:1008	arg1	interference					1010:1021	no drug excipients interference	991:1021	no drug excipients interference	991:1021	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	3	64	theme	eudragit	875:882	arg1	RL100					884:888	eudragit RL100	875:888	eudragit RL100	875:888	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	2	65	theme	particle	652:659	arg1	size					661:664	particle size	652:664	particle size	652:664	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	66	theme	formulated	774:783	arg1	microbeads					785:794	formulated microbeads	774:794	formulated microbeads	774:794	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	3	67	theme	alginate	862:869	arg1	concentration					838:850	concentration	838:850	concentration of sodium alginate and eudragit RL100	838:888	The impact of independent variables like concentration of sodium alginate and eudragit RL100 was examined over dependent responses.					
36892032	4	68	theme	FTIR	977:980	arg1	interpretation					940:953	The interpretation	936:953	The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads	936:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	6	69	theme	response	1272:1279	arg1	graph					1289:1293	response surface graph	1272:1293	response surface graph	1272:1293	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	6	70	theme	optimize	1419:1426	arg1	batch					1428:1432	the optimize batch	1415:1432	the optimize batch	1415:1432	The 32 central composite design was further used to obtain response surface graph and the values for the particle size, DEE and Drug release were retained as 0.197, 76.30 % and 92.15%, respectively for the optimize batch.					
36892032	4	71	theme	polyelectrolyte	1050:1064	arg1	microbeads					1074:1083	polyelectrolyte complex microbeads	1050:1083	polyelectrolyte complex microbeads	1050:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	2	72	from	10hr	742:745	arg1	Efficiency					683:692	Drug Entrapment Efficiency	667:692	Drug Entrapment Efficiency	667:692	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	Calorimetry					639:649	Differential Scanning Calorimetry	617:649	Differential Scanning Calorimetry	617:649	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	release					731:737	in-vitro drug release	717:737	in-vitro drug release	717:737	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	size					661:664	particle size	652:664	particle size	652:664	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	Microscope					605:614	Scanning Electron Microscope	587:614	Scanning Electron Microscope	587:614	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	diffraction					701:711	X-ray diffraction	695:711	X-ray diffraction	695:711	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	72	from	10hr	742:745	arg1	Spectroscopy					573:584	Infrared Spectroscopy	564:584	Infrared Spectroscopy	564:584	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	0	73	theme	Entrapment	91:100	arg1	Efficiency					102:111	Entrapment Efficiency	91:111	Entrapment Efficiency	91:111	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	7	74	dep	CONCLUSION	1435:1444	arg1	suggested					1457:1465	suggested	1457:1465	suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin)	1457:1623	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	75	theme	hydrophilic	1593:1603	arg1	Vildagliptin					1611:1622	Vildagliptin	1611:1622	Vildagliptin	1611:1622	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	7	75	theme	hydrophilic	1593:1603	arg1	drug					1605:1608	hydrophilic drug	1593:1608	hydrophilic drug (Vildagliptin)	1593:1623	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	2	76	theme	METHOD	539:544	arg1	Fourier					546:552	METHOD Fourier	539:552	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr	539:745	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	1	77	theme	Polyelectrolyte	382:396	arg1	microbeads					406:415	Polyelectrolyte complex microbeads	382:415	Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100	382:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	2	78	theme	Scanning	587:594	arg1	Microscope					605:614	Scanning Electron Microscope	587:614	Scanning Electron Microscope	587:614	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	2	79	theme	drug	726:729	arg1	release					731:737	in-vitro drug release	717:737	in-vitro drug release	717:737	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	1	80	dep	BACKGROUND	148:157	arg1	optimized					500:508	optimized	500:508	was optimized by Central composite design	496:536	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	1	80	dep	BACKGROUND	148:157	arg1	utilised					350:357	utilised	350:357	was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100	346:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	1	80	dep	BACKGROUND	148:157	arg1	research					171:178	The current research	159:178	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.	148:537	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	1	81	theme	microbeads	406:415	arg1	preparation					367:377	the preparation	363:377	the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100	363:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	4	82	dep	XRD	958:960	arg1	affirmed					982:989	affirmed	982:989	affirmed no drug excipients interference	982:1021	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	4	82	dep	XRD	958:960	arg1	confirmed					1027:1035	confirmed	1027:1035	confirmed formation of polyelectrolyte complex microbeads	1027:1083	RESULT The interpretation of XRD, SEM, DSC, and FTIR affirmed no drug excipients interference and confirmed formation of polyelectrolyte complex microbeads.					
36892032	1	83	theme	Vildagliptin	420:431	arg1	microbeads					406:415	Polyelectrolyte complex microbeads	382:415	Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100	382:472	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	8	84	theme	microbeads	1776:1785	arg1	systems					1728:1734	optimal drug delivery systems	1706:1734	optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1706:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	0	85	theme	Novel	39:43	arg1	Microbeads					69:78	Novel Polyelectrolyte Complex Microbeads	39:78	Novel Polyelectrolyte Complex Microbeads	39:78	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	1	86	theme	gelation	327:334	arg1	technique					336:344	Ionotropic gelation technique	316:344	Ionotropic gelation technique	316:344	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	7	87	theme	entrapment	1568:1577	arg1	efficiency					1579:1588	the entrapment efficiency	1564:1588	the entrapment efficiency of hydrophilic drug (Vildagliptin)	1564:1623	CONCLUSION The result suggested the combination of two polymers (Sodium alginate and Eudragit RL100) were suitable for improving the entrapment efficiency of hydrophilic drug (Vildagliptin).					
36892032	0	88	theme	Complex	61:67	arg1	Microbeads					69:78	Novel Polyelectrolyte Complex Microbeads	39:78	Novel Polyelectrolyte Complex Microbeads	39:78	Design And Statistical Optimization Of Novel Polyelectrolyte Complex Microbeads To Improve Entrapment Efficiency And Release Study Of Vildagliptin.					
36892032	2	89	dep	Fourier	546:552	arg1	Transform					554:562	Transform	554:562	Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr	554:745	METHOD Fourier Transform Infrared Spectroscopy, Scanning Electron Microscope, Differential Scanning Calorimetry, particle size, Drug Entrapment Efficiency, X-ray diffraction and in-vitro drug release at 10hr were chosen for evaluating formulated microbeads.					
36892032	8	90	theme	central	1630:1636	arg1	CCD					1656:1658	CCD	1656:1658	CCD	1656:1658	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	8	90	theme	central	1630:1636	arg1	design					1648:1653	central composite design	1630:1653	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	1	91	theme	study	249:253	arg1	improvement					195:205	the improvement	191:205	the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective	191:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
36892032	8	92	theme	design	1648:1653	arg1	tool					1687:1690	an effective tool	1674:1690	an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads	1674:1785	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	8	92	theme	design	1648:1653	arg1	technique					1661:1669	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique	1626:1669	The central composite design (CCD) technique is an effective tool for obtaining optimal drug delivery systems of Vildagliptin polyelectrolyte complex microbeads.					
36892032	1	93	theme	hydrophilic	258:268	arg1	drug					270:273	hydrophilic drug	258:273	hydrophilic drug through polymer complextation Objective	258:313	BACKGROUND The current research focused on the improvement of drug entrapment efficiency and release study of hydrophilic drug through polymer complextation Objective: Ionotropic gelation technique was utilised for the preparation of Polyelectrolyte complex microbeads of Vildagliptin using Sodium alginate and Eudragit RL100 and their performance was optimized by Central composite design.					
35930741	0	0	theme	Shape	98:102	arg1	Cryogel					111:117	Shape Memory Cryogel	98:117	Shape Memory Cryogel	98:117	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	5	1	theme	in	679:680	arg1	SAXS					717:720	SAXS	717:720	SAXS	717:720	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	1	theme	in	679:680	arg1	scattering					705:714	in situ small-angle X-ray scattering	679:714	in situ small-angle X-ray scattering (SAXS)	679:721	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	8	2	theme	nanocellulose-chitosan	1068:1089	arg1	cryogel					1114:1120	cryogel	1114:1120	cryogel	1114:1120	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	2	theme	nanocellulose-chitosan	1068:1089	arg1	hydrogel					1101:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	2	theme	nanocellulose-chitosan	1068:1089	arg1	biomaterials					1152:1163	injectable and degradable biomaterials	1126:1163	injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications	1126:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	6	3	theme	×	908:908	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	3	theme	×	908:908	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	4	from	recoverable	969:979	arg1	water					990:994	37 °C water	984:994	37 °C water	984:994	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	8	5	theme	medical	1217:1223	arg1	applications					1225:1236	potential medical applications	1207:1236	potential medical applications	1207:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	5	6	theme	crystalline	803:813	arg1	structure					815:823	the induced crystalline structure	791:823	the induced crystalline structure during the shape memory program	791:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	6	7	theme	mm	905:906	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	7	theme	mm	905:906	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	5	8	theme	small-angle	687:697	arg1	SAXS					717:720	SAXS	717:720	SAXS	717:720	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	8	theme	small-angle	687:697	arg1	scattering					705:714	in situ small-angle X-ray scattering	679:714	in situ small-angle X-ray scattering (SAXS)	679:721	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	6	9	theme	syringe	950:956	arg1	needle					958:963	a 16 G syringe needle	943:963	a 16 G syringe needle	943:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	0	10	theme	Memory	104:109	arg1	Cryogel					111:117	Shape Memory Cryogel	98:117	Shape Memory Cryogel	98:117	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	5	11	theme	X-ray	699:703	arg1	SAXS					717:720	SAXS	717:720	SAXS	717:720	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	11	theme	X-ray	699:703	arg1	scattering					705:714	in situ small-angle X-ray scattering	679:714	in situ small-angle X-ray scattering (SAXS)	679:721	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	2	12	theme	effective	327:335	arg1	self-healing					337:348	effective self-healing	327:348	effective self-healing (∼100% efficiency)	327:367	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	2	12	theme	effective	327:335	arg1	efficiency					357:366	∼100% efficiency	351:366	∼100% efficiency	351:366	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	8	13	with	biomaterials	1152:1163	arg1	properties					1192:1201	adjustable mechanical properties	1170:1201	adjustable mechanical properties	1170:1201	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	6	14	theme	G	948:948	arg1	needle					958:963	a 16 G syringe needle	943:963	a 16 G syringe needle	943:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	7	15	theme	cell	1051:1054	arg1	growth					1056:1061	cell growth	1051:1061	cell growth	1051:1061	Moreover, the cryogel was cytocompatible and promoted cell growth.					
35930741	6	16	with	cryogel	875:881	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	16	with	cryogel	875:881	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	8	17	theme	degradable	1141:1150	arg1	cryogel					1114:1120	cryogel	1114:1120	cryogel	1114:1120	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	17	theme	degradable	1141:1150	arg1	hydrogel					1101:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	17	theme	degradable	1141:1150	arg1	biomaterials					1152:1163	injectable and degradable biomaterials	1126:1163	injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications	1126:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	6	18	theme	memory	868:873	arg1	cryogel					875:881	The shape memory cryogel	858:881	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	858:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	18	theme	memory	868:873	arg1	recoverable					969:979	recoverable	969:979	recoverable	969:979	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	3	19	theme	large	439:443	arg1	absorption					451:460	large water absorption	439:460	large water absorption (>4300%)	439:469	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	19	theme	large	439:443	arg1	%					468:468	>4300%	463:468	>4300%	463:468	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	0	20	theme	Cellulose	15:23	arg1	Nanofibers					25:34	Functionalized Cellulose Nanofibers	0:34	Functionalized Cellulose Nanofibers as Crosslinkers	0:50	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	6	21	theme	large	890:894	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	21	theme	large	890:894	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	5	22	theme	induced	616:622	arg1	memory					630:635	thermally induced shape memory	606:635	thermally induced shape memory	606:635	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	0	23	theme	Functionalized	0:13	arg1	Nanofibers					25:34	Functionalized Cellulose Nanofibers	0:34	Functionalized Cellulose Nanofibers as Crosslinkers	0:50	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	5	24	theme	shape	624:628	arg1	memory					630:635	thermally induced shape memory	606:635	thermally induced shape memory	606:635	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	2	25	theme	%	355:355	arg1	self-healing					337:348	effective self-healing	327:348	effective self-healing (∼100% efficiency)	327:367	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	2	25	theme	%	355:355	arg1	efficiency					357:366	∼100% efficiency	351:366	∼100% efficiency	351:366	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	3	26	theme	macroporous	416:426	arg1	structure					428:436	macroporous structure	416:436	macroporous structure	416:436	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	2	27	contain	possessed	317:325	arg2	efficiency					357:366	∼100% efficiency	351:366	∼100% efficiency	351:366	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	2	27	contain	possessed	317:325	arg2	properties					388:397	shear-thinning properties	373:397	shear-thinning properties	373:397	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	2	27	contain	possessed	317:325	arg1	hydrogel					308:315	The hydrogel	304:315	The hydrogel	304:315	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	2	27	contain	possessed	317:325	arg2	self-healing					337:348	effective self-healing	327:348	effective self-healing (∼100% efficiency)	327:367	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	5	28	theme	memory	630:635	arg1	mechanism					642:650	the mechanism	638:650	the mechanism	638:650	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	28	theme	memory	630:635	arg1	changes					765:771	changes	765:771	changes in orientation of the induced crystalline structure during the shape memory program	765:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	2	29	theme	∼100	351:354	arg1	%					355:355	%	355:355	%	355:355	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	5	30	theme	memory	842:847	arg1	program					849:855	the shape memory program	832:855	the shape memory program	832:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	31	theme	wide-angle	727:736	arg1	WAXS					756:759	WAXS	756:759	WAXS	756:759	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	31	theme	wide-angle	727:736	arg1	scattering					744:753	wide-angle X-ray scattering	727:753	wide-angle X-ray scattering (WAXS)	727:760	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	1	32	theme	Cellulose	120:128	arg1	crosslinker					209:219	the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan	205:301	the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan	205:301	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	32	theme	Cellulose	120:128	arg1	nanofibers					130:139	Cellulose nanofibers	120:139	Cellulose nanofibers functionalized with multiple aldehyde group	120:183	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	33	theme	composite	232:240	arg1	hydrogel					255:262	composite self-healing hydrogel	232:262	composite self-healing hydrogel	232:262	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	8	34	theme	potential	1207:1215	arg1	applications					1225:1236	potential medical applications	1207:1236	potential medical applications	1207:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	5	35	theme	X-ray	738:742	arg1	WAXS					756:759	WAXS	756:759	WAXS	756:759	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	35	theme	X-ray	738:742	arg1	scattering					744:753	wide-angle X-ray scattering	727:753	wide-angle X-ray scattering (WAXS)	727:760	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	3	36	theme	high	476:479	arg1	compressibility					481:495	high compressibility	476:495	high compressibility	476:495	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	1	37	theme	self-healing	242:253	arg1	hydrogel					255:262	composite self-healing hydrogel	232:262	composite self-healing hydrogel	232:262	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	5	38	theme	induced	795:801	arg1	structure					815:823	the induced crystalline structure	791:823	the induced crystalline structure during the shape memory program	791:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	1	39	from	chitosan	294:301	arg1	cryogel					281:287	shape memory cryogel	268:287	shape memory cryogel	268:287	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	39	from	chitosan	294:301	arg1	hydrogel					255:262	composite self-healing hydrogel	232:262	composite self-healing hydrogel	232:262	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	5	40	theme	shape	836:840	arg1	program					849:855	the shape memory program	832:855	the shape memory program	832:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	41	theme	nanocellulose/chitosan	569:590	arg1	cryogel					560:566	the cryogel	556:566	the cryogel (nanocellulose/chitosan 1:6)	556:595	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	41	theme	nanocellulose/chitosan	569:590	arg1	1:6					592:594	nanocellulose/chitosan 1:6	569:594	nanocellulose/chitosan 1:6	569:594	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	3	42	theme	water	445:449	arg1	absorption					451:460	large water absorption	439:460	large water absorption (>4300%)	439:469	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	42	theme	water	445:449	arg1	%					468:468	>4300%	463:468	>4300%	463:468	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	0	43	theme	Self-Healing	72:83	arg1	Hydrogel					85:92	Chitosan Self-Healing Hydrogel	63:92	Chitosan Self-Healing Hydrogel	63:92	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	5	44	theme	structure	815:823	arg1	orientation					776:786	orientation	776:786	orientation of the induced crystalline structure during the shape memory program	776:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	6	45	theme	shape	862:866	arg1	cryogel					875:881	The shape memory cryogel	858:881	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	858:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	45	theme	shape	862:866	arg1	recoverable					969:979	recoverable	969:979	recoverable	969:979	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	3	46	contain	had	412:414	arg2	%					468:468	>4300%	463:468	>4300%	463:468	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	46	contain	had	412:414	arg2	compressibility					481:495	high compressibility	476:495	high compressibility	476:495	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	46	contain	had	412:414	arg1	cryogel					404:410	The cryogel	400:410	The cryogel	400:410	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	46	contain	had	412:414	arg2	absorption					451:460	large water absorption	439:460	large water absorption (>4300%)	439:469	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	3	46	contain	had	412:414	arg2	structure					428:436	macroporous structure	416:436	macroporous structure	416:436	The cryogel had macroporous structure, large water absorption (>4300%), and high compressibility.					
35930741	2	47	theme	shear-thinning	373:386	arg1	properties					388:397	shear-thinning properties	373:397	shear-thinning properties	373:397	The hydrogel possessed effective self-healing (∼100% efficiency) and shear-thinning properties.					
35930741	6	48	theme	×	916:916	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	48	theme	×	916:916	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	8	49	theme	composite	1091:1099	arg1	cryogel					1114:1120	cryogel	1114:1120	cryogel	1114:1120	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	49	theme	composite	1091:1099	arg1	hydrogel					1101:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	49	theme	composite	1091:1099	arg1	biomaterials					1152:1163	injectable and degradable biomaterials	1126:1163	injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications	1126:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	6	50	from	water	990:994	arg1	cryogel					875:881	The shape memory cryogel	858:881	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	858:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	50	from	water	990:994	arg1	recoverable					969:979	recoverable	969:979	recoverable	969:979	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	51	theme	°C	987:988	arg1	water					990:994	37 °C water	984:994	37 °C water	984:994	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	5	52	dep	in	679:680	arg1	situ					682:685	situ	682:685	situ	682:685	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	5	53	from	changes	765:771	arg1	orientation					776:786	orientation	776:786	orientation of the induced crystalline structure during the shape memory program	776:855	In particular, the cryogel (nanocellulose/chitosan 1:6) revealed thermally induced shape memory, the mechanism of which was elucidated by in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) as changes in orientation of the induced crystalline structure during the shape memory program.					
35930741	1	54	theme	multiple	161:168	arg1	group					179:183	multiple aldehyde group	161:183	multiple aldehyde group	161:183	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	55	theme	shape	268:272	arg1	cryogel					281:287	shape memory cryogel	268:287	shape memory cryogel	268:287	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	56	theme	aldehyde	170:177	arg1	group					179:183	multiple aldehyde group	161:183	multiple aldehyde group	161:183	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	1	57	theme	memory	274:279	arg1	cryogel					281:287	shape memory cryogel	268:287	shape memory cryogel	268:287	Cellulose nanofibers functionalized with multiple aldehyde group were synthesized as the crosslinker to produce composite self-healing hydrogel and shape memory cryogel from chitosan.					
35930741	0	58	theme	Chitosan	63:70	arg1	Hydrogel					85:92	Chitosan Self-Healing Hydrogel	63:92	Chitosan Self-Healing Hydrogel	63:92	Functionalized Cellulose Nanofibers as Crosslinkers to Produce Chitosan Self-Healing Hydrogel and Shape Memory Cryogel.					
35930741	6	59	theme	mm	913:914	arg1	mm					922:923	15 mm × 10 mm × 1.1 mm	902:923	15 mm × 10 mm × 1.1 mm	902:923	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	6	59	theme	mm	913:914	arg1	size					896:899	a large size	888:899	a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle	888:963	The shape memory cryogel with a large size (15 mm × 10 mm × 1.1 mm) injected through a 16 G syringe needle was recoverable in 37 °C water.					
35930741	8	60	theme	mechanical	1181:1190	arg1	properties					1192:1201	adjustable mechanical properties	1170:1201	adjustable mechanical properties	1170:1201	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	61	theme	adjustable	1170:1179	arg1	properties					1192:1201	adjustable mechanical properties	1170:1201	adjustable mechanical properties	1170:1201	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	62	theme	injectable	1126:1135	arg1	cryogel					1114:1120	cryogel	1114:1120	cryogel	1114:1120	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	62	theme	injectable	1126:1135	arg1	hydrogel					1101:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel	1064:1108	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
35930741	8	62	theme	injectable	1126:1135	arg1	biomaterials					1152:1163	injectable and degradable biomaterials	1126:1163	injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications	1126:1236	The nanocellulose-chitosan composite hydrogel and cryogel are injectable and degradable biomaterials with adjustable mechanical properties for potential medical applications.					
34988576	2	0	from	7.5	328:330	arg1	value					309:313	the pH value	302:313	the pH value	302:313	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	4	1	theme	umbilical	742:750	arg1	HUVECs					728:733	HUVECs	728:733	HUVECs (human umbilical vein endothelial cells)	728:774	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	1	theme	umbilical	742:750	arg1	cells					769:773	human umbilical vein endothelial cells	736:773	human umbilical vein endothelial cells	736:773	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	1	2	theme	chitosan	120:127	arg1	role					112:115	the role	108:115	the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing	108:208	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	7	3	theme	wound	1206:1210	arg1	healing					1212:1218	wound healing	1206:1218	wound healing	1206:1218	This novel paste is expected to provide a promising alternative for wound healing.					
34988576	1	4	theme	paste	186:190	arg1	BG					182:183	BG	182:183	BG	182:183	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	1	4	theme	paste	186:190	arg1	glass					175:179	bioactive glass	165:179	bioactive glass (BG) paste for wound healing	165:208	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	0	5	theme	paste	69:73	arg1	evaluation					21:30	In vivo and in vitro evaluation	0:30	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.	0:92	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	4	6	theme	human	736:740	arg1	HUVECs					728:733	HUVECs	728:733	HUVECs (human umbilical vein endothelial cells)	728:774	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	6	theme	human	736:740	arg1	cells					769:773	human umbilical vein endothelial cells	736:773	human umbilical vein endothelial cells	736:773	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	3	7	contain	had	463:465	arg2	affinity					498:505	better affinity	491:505	better affinity	491:505	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	3	7	contain	had	463:465	arg2	bio-adhesion					474:485	higher bio-adhesion	467:485	higher bio-adhesion	467:485	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	3	7	contain	had	463:465	arg1	paste					457:461	the composite paste	443:461	the composite paste	443:461	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	6	8	theme	rat	958:960	arg1	model					949:953	The burn-wound model	934:953	The burn-wound model of rat	934:960	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	4	9	theme	endothelial	757:767	arg1	HUVECs					728:733	HUVECs	728:733	HUVECs (human umbilical vein endothelial cells)	728:774	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	9	theme	endothelial	757:767	arg1	cells					769:773	human umbilical vein endothelial cells	736:773	human umbilical vein endothelial cells	736:773	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	10	theme	antibacterial	644:656	arg1	activity					658:665	stronger antibacterial activity	635:665	stronger antibacterial activity	635:665	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	1	11	theme	wound	196:200	arg1	healing					202:208	wound healing	196:208	wound healing	196:208	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	0	12	theme	wound	79:83	arg1	healing					85:91	wound healing	79:91	wound healing	79:91	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	4	13	theme	vein	752:755	arg1	HUVECs					728:733	HUVECs	728:733	HUVECs (human umbilical vein endothelial cells)	728:774	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	13	theme	vein	752:755	arg1	cells					769:773	human umbilical vein endothelial cells	736:773	human umbilical vein endothelial cells	736:773	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	14	theme	stronger	635:642	arg1	activity					658:665	stronger antibacterial activity	635:665	stronger antibacterial activity	635:665	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	6	15	theme	IL-6	1123:1126	arg1	staining					1128:1135	IL-6 staining	1123:1135	IL-6 staining	1123:1135	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	4	16	theme	composite	615:623	arg1	paste					625:629	the composite paste	611:629	the composite paste	611:629	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	2	17	theme	pH	306:307	arg1	value					309:313	the pH value	302:313	the pH value	302:313	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	2	18	theme	paste	388:392	arg1	bioactivity					370:380	the bioactivity	366:380	the bioactivity of BG paste in vitro	366:401	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	2	19	dep	7.5	328:330	arg1	to					325:326	to	325:326	to	325:326	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	3	20	theme	rheological	408:418	arg1	properties					420:429	The rheological properties	404:429	The rheological properties	404:429	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	6	21	theme	burn-wound	938:947	arg1	model					949:953	The burn-wound model	934:953	The burn-wound model of rat	934:960	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	0	22	theme	glass	63:67	arg1	paste					69:73	chitosan-modified bioactive glass paste	35:73	chitosan-modified bioactive glass paste	35:73	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	3	23	theme	composite	447:455	arg1	paste					457:461	the composite paste	443:461	the composite paste	443:461	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	4	24	dep	CS	679:680	arg1	paste					688:692	paste	688:692	paste	688:692	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	0	25	theme	In	0:1	arg1	evaluation					21:30	In vivo and in vitro evaluation	0:30	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.	0:92	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	6	26	theme	wound	1053:1057	arg1	healing					1059:1065	wound healing	1053:1065	wound healing	1053:1065	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	4	27	theme	HUVECs	728:733	arg1	proliferation					711:723	the proliferation	707:723	the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells)	707:824	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	2	28	theme	CS	287:288	arg1	addition					275:282	the addition	271:282	the addition of CS	271:288	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	0	29	theme	in	12:13	arg1	evaluation					21:30	In vivo and in vitro evaluation	0:30	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.	0:92	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	4	30	contain	had	631:633	arg1	paste					625:629	the composite paste	611:629	the composite paste	611:629	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	30	contain	had	631:633	arg2	activity					658:665	stronger antibacterial activity	635:665	stronger antibacterial activity	635:665	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	31	theme	human	787:791	arg1	cells					819:823	human immortalized keratinocyte cells	787:823	human immortalized keratinocyte cells	787:823	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	31	theme	human	787:791	arg1	HaCat					780:784	HaCat	780:784	HaCat (human immortalized keratinocyte cells)	780:824	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	6	32	theme	obvious	1075:1081	arg1	inflammation					1083:1094	obvious inflammation	1075:1094	obvious inflammation according to the IL-1β and IL-6 staining	1075:1135	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	2	33	theme	in	232:233	arg1	evaluation					241:250	in vitro evaluation	232:250	in vitro evaluation	232:250	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	2	34	from	bioactivity	370:380	arg1	vitro					397:401	vitro	397:401	vitro	397:401	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	6	35	theme	in	991:992	arg1	activity					999:1006	in vivo activity	991:1006	in vivo activity	991:1006	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	4	36	theme	keratinocyte	806:817	arg1	cells					819:823	human immortalized keratinocyte cells	787:823	human immortalized keratinocyte cells	787:823	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	36	theme	keratinocyte	806:817	arg1	HaCat					780:784	HaCat	780:784	HaCat (human immortalized keratinocyte cells)	780:824	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	5	37	theme	HUVECs	887:892	arg1	proliferation					870:882	the proliferation	866:882	the proliferation of HUVECs	866:892	Comparatively, the effect of promoting the proliferation of HUVECs is more significant than that of HaCat.					
34988576	7	38	theme	promising	1180:1188	arg1	alternative					1190:1200	a promising alternative	1178:1200	a promising alternative for wound healing	1178:1218	This novel paste is expected to provide a promising alternative for wound healing.					
34988576	4	39	theme	immortalized	793:804	arg1	cells					819:823	human immortalized keratinocyte cells	787:823	human immortalized keratinocyte cells	787:823	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	4	39	theme	immortalized	793:804	arg1	HaCat					780:784	HaCat	780:784	HaCat (human immortalized keratinocyte cells)	780:824	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	3	40	theme	skin	516:519	arg1	surface					521:527	the skin surface	512:527	the skin surface	512:527	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	6	41	dep	IL-1β	1113:1117	arg1	the					1109:1111	the	1109:1111	the	1109:1111	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	1	42	theme	bioactive	165:173	arg1	BG					182:183	BG	182:183	BG	182:183	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	1	42	theme	bioactive	165:173	arg1	glass					175:179	bioactive glass	165:179	bioactive glass (BG) paste for wound healing	165:208	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	0	43	theme	chitosan-modified	35:51	arg1	paste					69:73	chitosan-modified bioactive glass paste	35:73	chitosan-modified bioactive glass paste	35:73	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	2	44	dep	in	232:233	arg1	vitro					235:239	vitro	235:239	vitro	235:239	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	6	45	theme	CS	1029:1030	arg1	addition					1017:1024	the addition	1013:1024	the addition of CS	1013:1030	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	3	46	theme	higher	467:472	arg1	bio-adhesion					474:485	higher bio-adhesion	467:485	higher bio-adhesion	467:485	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	4	47	theme	property	579:586	arg1	evaluation					588:597	The antibacterial property evaluation	561:597	The antibacterial property evaluation	561:597	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	6	48	dep	in	991:992	arg1	vivo					994:997	vivo	994:997	vivo	994:997	The burn-wound model of rat was developed for evaluating in vivo activity, and the addition of CS effectively promoted wound healing without obvious inflammation according to the IL-1β and IL-6 staining.					
34988576	4	49	theme	HaCat	780:784	arg1	proliferation					711:723	the proliferation	707:723	the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells)	707:824	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	3	50	theme	BG	551:552	arg1	paste					554:558	the BG paste	547:558	the BG paste	547:558	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	0	51	dep	in	12:13	arg1	vitro					15:19	vitro	15:19	vitro	15:19	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	4	52	theme	antibacterial	565:577	arg1	evaluation					588:597	The antibacterial property evaluation	561:597	The antibacterial property evaluation	561:597	The antibacterial property evaluation showed that the composite paste had stronger antibacterial activity than either CS or BG paste and promoted the proliferation of HUVECs (human umbilical vein endothelial cells) and HaCat (human immortalized keratinocyte cells).					
34988576	1	53	theme	glass	175:179	arg1	properties					151:160	the properties	147:160	the properties of bioactive glass (BG) paste for wound healing	147:208	In this work, the role of chitosan (CS) in improving the properties of bioactive glass (BG) paste for wound healing was studied.					
34988576	7	54	theme	novel	1143:1147	arg1	paste					1149:1153	This novel paste	1138:1153	This novel paste	1138:1153	This novel paste is expected to provide a promising alternative for wound healing.					
34988576	2	55	theme	BG	385:386	arg1	paste					388:392	BG paste	385:392	BG paste	385:392	Based on in vitro evaluation, it was found that the addition of CS neutralizes the pH value from 11.0 to 7.5, which did not lead to decreasing the bioactivity of BG paste in vitro.					
34988576	3	56	theme	better	491:496	arg1	affinity					498:505	better affinity	491:505	better affinity	491:505	The rheological properties showed that the composite paste had higher bio-adhesion and better affinity with the skin surface than either CS or the BG paste.					
34988576	0	57	theme	bioactive	53:61	arg1	paste					69:73	chitosan-modified bioactive glass paste	35:73	chitosan-modified bioactive glass paste	35:73	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
34988576	0	58	dep	In	0:1	arg1	vivo					3:6	vivo	3:6	vivo	3:6	In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing.					
35306804	0	0	theme	Electromagnetic	95:109	arg1	Shielding					124:132	Electromagnetic Interference Shielding	95:132	Electromagnetic Interference Shielding	95:132	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	2	1	dep	hot-pressing	500:511	arg1	processes					553:561	dipping processes	545:561	dipping processes	545:561	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	4	2	theme	dB	1170:1171	arg1	value					1158:1162	shielding effectiveness value	1134:1162	shielding effectiveness value of 46 dB with a filler content of 21.6 wt %	1134:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	1	3	theme	shielding	199:207	arg1	films					209:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	4	4	theme	maximum	1057:1063	arg1	strength					1073:1080	maximum tensile strength	1057:1080	maximum tensile strength of 511.8 MPa	1057:1093	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	5	theme	conductive	919:928	arg1	network					930:936	the compact conductive network	907:936	the compact conductive network	907:936	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	6	theme	higher	866:871	arg1	degree					873:878	The higher degree	862:878	The higher degree of nanofiber alignment and the compact conductive network	862:936	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	3	7	theme	incident	843:850	arg1	waves					855:859	incident EM waves	843:859	incident EM waves	843:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	5	8	theme	long-term	1449:1457	arg1	wearing					1459:1465	the long-term wearing	1445:1465	the long-term wearing	1445:1465	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	2	9	theme	@	627:627	arg1	CS-PDMS					628:634	d-AgNWs@CS-PDMS	620:634	d-AgNWs@CS-PDMS	620:634	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	9	theme	@	627:627	arg1	film					614:617	cellulosic film	603:617	cellulosic film (d-AgNWs@CS-PDMS)	603:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	5	10	theme	composite	1393:1401	arg1	film					1403:1406	the composite film	1389:1406	the composite film	1389:1406	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	11	theme	PDMS	1321:1324	arg1	layer					1326:1330	the PDMS layer	1317:1330	the PDMS layer	1317:1330	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	1	12	theme	wearable	296:303	arg1	electronics					305:315	wearable electronics	296:315	wearable electronics	296:315	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	0	13	theme	Interference	111:122	arg1	Shielding					124:132	Electromagnetic Interference Shielding	95:132	Electromagnetic Interference Shielding	95:132	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	4	14	dep	performance	1121:1131	arg1	value					1158:1162	shielding effectiveness value	1134:1162	shielding effectiveness value of 46 dB with a filler content of 21.6 wt %	1134:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	2	15	theme	d-AgNWs	620:626	arg1	CS-PDMS					628:634	d-AgNWs@CS-PDMS	620:634	d-AgNWs@CS-PDMS	620:634	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	15	theme	d-AgNWs	620:626	arg1	film					614:617	cellulosic film	603:617	cellulosic film (d-AgNWs@CS-PDMS)	603:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	5	16	theme	film	1403:1406	arg1	activity					1377:1384	antibacterial activity	1363:1384	antibacterial activity	1363:1384	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	16	theme	film	1403:1406	arg1	hydrophobicity					1344:1357	hydrophobicity	1344:1357	hydrophobicity	1344:1357	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	4	17	theme	shielding	1134:1142	arg1	value					1158:1162	shielding effectiveness value	1134:1162	shielding effectiveness value of 46 dB with a filler content of 21.6 wt %	1134:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	1	18	theme	electronics	305:315	arg1	fields					286:291	the fields	282:291	the fields of wearable electronics	282:315	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	2	19	theme	dipping	545:551	arg1	processes					553:561	dipping processes	545:561	dipping processes	545:561	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	5	20	theme	AgNWs	1279:1283	arg1	network					1285:1291	an intensive AgNWs network	1266:1291	an intensive AgNWs network	1266:1291	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	4	21	theme	X	1216:1216	arg1	GHz					1233:1235	8.2-12.4 GHz	1224:1235	8.2-12.4 GHz	1224:1235	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	21	theme	X	1216:1216	arg1	band					1218:1221	the X band	1212:1221	the X band (8.2-12.4 GHz)	1212:1236	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	5	22	theme	network	1285:1291	arg1	existence					1253:1261	the existence	1249:1261	the existence of an intensive AgNWs network	1249:1291	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	22	theme	network	1285:1291	arg1	introduction					1301:1312	the introduction	1297:1312	the introduction of the PDMS layer	1297:1330	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	2	23	theme	aligned	421:427	arg1	scaffold					439:446	the highly aligned cellulose scaffold	410:446	the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS)	410:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	23	theme	aligned	421:427	arg1	CS					449:450	CS	449:450	CS	449:450	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	4	24	theme	composite	1005:1013	arg1	film					1015:1018	the composite film	1001:1018	the composite film	1001:1018	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	25	theme	wt	1203:1204	arg1	%					1206:1206	21.6 wt %	1198:1206	21.6 wt %	1198:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	26	with	dB	1170:1171	arg1	content					1187:1193	a filler content	1178:1193	a filler content of 21.6 wt %	1178:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	1	27	theme	superior	220:227	arg1	strength					240:247	superior mechanical strength	220:247	superior mechanical strength	220:247	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	0	28	theme	Ultrastrong	3:13	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	5	29	theme	antibacterial	1363:1375	arg1	activity					1377:1384	antibacterial activity	1363:1384	antibacterial activity	1363:1384	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	2	30	theme	silver	347:352	arg1	AgNWs					365:369	AgNWs	365:369	AgNWs	365:369	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	30	theme	silver	347:352	arg1	nanowires					354:362	the conductive silver nanowires	332:362	the conductive silver nanowires (AgNWs)	332:370	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	4	31	theme	effectiveness	1144:1156	arg1	value					1158:1162	shielding effectiveness value	1134:1162	shielding effectiveness value of 46 dB with a filler content of 21.6 wt %	1134:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	1	32	theme	mechanical	229:238	arg1	strength					240:247	superior mechanical strength	220:247	superior mechanical strength	220:247	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	4	33	theme	striking	1025:1032	arg1	properties					1045:1054	striking mechanical properties	1025:1054	striking mechanical properties (maximum tensile strength of 511.8 MPa)	1025:1094	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	6	34	theme	EMI	1568:1570	arg1	material					1582:1589	an EMI shielding material	1565:1589	an EMI shielding material used for wearable devices	1565:1615	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	34	theme	EMI	1568:1570	arg1	potential					1552:1560	high potential	1547:1560	high potential	1547:1560	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	2	35	theme	conductive	336:345	arg1	AgNWs					365:369	AgNWs	365:369	AgNWs	365:369	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	35	theme	conductive	336:345	arg1	nanowires					354:362	the conductive silver nanowires	332:362	the conductive silver nanowires (AgNWs)	332:370	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	6	36	theme	d-AgNWs	1512:1518	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	37	contain	has	1543:1545	arg2	potential					1552:1560	high potential	1547:1560	high potential	1547:1560	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	37	contain	has	1543:1545	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	37	contain	has	1543:1545	arg2	material					1582:1589	an EMI shielding material	1565:1589	an EMI shielding material used for wearable devices	1565:1615	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	0	38	theme	Antibacterial	19:31	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	4	39	theme	network	930:936	arg1	degree					873:878	The higher degree	862:878	The higher degree of nanofiber alignment and the compact conductive network	862:936	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	40	theme	%	1206:1206	arg1	content					1187:1193	a filler content	1178:1193	a filler content of 21.6 wt %	1178:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	5	41	dep	health	1426:1431	arg1	concerns					1433:1440	concerns	1433:1440	concerns	1433:1440	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	4	42	theme	superb	1100:1105	arg1	EMI					1107:1109	superb EMI	1100:1109	superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz)	1100:1236	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	3	43	theme	hydrogen	750:757	arg1	conducive					812:820	conducive	812:820	conducive	812:820	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	3	43	theme	hydrogen	750:757	arg1	bonding					759:765	the hydrogen bonding	746:765	the hydrogen bonding	746:765	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	2	44	theme	outstanding	577:587	arg1	EMI					589:591	the outstanding EMI	573:591	the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS)	573:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	3	45	theme	AgNWs	678:682	arg1	result					736:741	a result	734:741	a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves	734:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	3	45	theme	AgNWs	678:682	arg1	pathway					667:673	The consecutively conductive pathway	638:673	The consecutively conductive pathway of AgNWs	638:682	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	0	46	theme	Nanowire/Aligned	40:55	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	3	47	theme	bonding	759:765	arg1	result					736:741	a result	734:741	a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves	734:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	3	47	theme	bonding	759:765	arg1	pathway					667:673	The consecutively conductive pathway	638:673	The consecutively conductive pathway of AgNWs	638:682	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	6	48	theme	shielding	1572:1580	arg1	material					1582:1589	an EMI shielding material	1565:1589	an EMI shielding material used for wearable devices	1565:1615	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	48	theme	shielding	1572:1580	arg1	potential					1552:1560	high potential	1547:1560	high potential	1547:1560	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	5	49	theme	serious	1418:1424	arg1	health					1426:1431	serious health concerns	1418:1440	serious health concerns	1418:1440	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	50	theme	layer	1326:1330	arg1	existence					1253:1261	the existence	1249:1261	the existence of an intensive AgNWs network	1249:1291	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	50	theme	layer	1326:1330	arg1	introduction					1301:1312	the introduction	1297:1312	the introduction of the PDMS layer	1297:1330	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	5	51	theme	intensive	1269:1277	arg1	network					1285:1291	an intensive AgNWs network	1266:1291	an intensive AgNWs network	1266:1291	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	0	52	theme	Silver	33:38	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	5	53	dep	hydrophobicity	1344:1357	arg1	the					1340:1342	the	1340:1342	the	1340:1342	Moreover, the existence of an intensive AgNWs network and the introduction of the PDMS layer improve the hydrophobicity and antibacterial activity of the composite film, avoiding serious health concerns in the long-term wearing.					
35306804	4	54	theme	filler	1180:1185	arg1	content					1187:1193	a filler content	1178:1193	a filler content of 21.6 wt %	1178:1206	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	2	55	theme	cellulose	429:437	arg1	scaffold					439:446	the highly aligned cellulose scaffold	410:446	the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS)	410:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	55	theme	cellulose	429:437	arg1	CS					449:450	CS	449:450	CS	449:450	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	0	56	theme	Scaffold	67:74	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	4	57	theme	nanofiber	883:891	arg1	alignment					893:901	nanofiber alignment	883:901	nanofiber alignment	883:901	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	58	theme	compact	911:917	arg1	network					930:936	the compact conductive network	907:936	the compact conductive network	907:936	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	1	59	theme	multifunctional	148:162	arg1	films					209:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	0	60	theme	Cellulose	57:65	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	4	61	theme	alignment	893:901	arg1	degree					873:878	The higher degree	862:878	The higher degree of nanofiber alignment and the compact conductive network	862:936	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	62	dep	properties	1045:1054	arg1	strength					1073:1080	maximum tensile strength	1057:1080	maximum tensile strength of 511.8 MPa	1057:1093	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	6	63	theme	high	1547:1550	arg1	material					1582:1589	an EMI shielding material	1565:1589	an EMI shielding material used for wearable devices	1565:1615	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	63	theme	high	1547:1550	arg1	potential					1552:1560	high potential	1547:1560	high potential	1547:1560	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	1	64	theme	electromagnetic	164:178	arg1	films					209:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	4	65	theme	MPa	1091:1093	arg1	strength					1073:1080	maximum tensile strength	1057:1080	maximum tensile strength of 511.8 MPa	1057:1093	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	3	66	theme	cellulose	785:793	arg1	fibers					795:800	cellulose fibers	785:800	cellulose fibers	785:800	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	2	67	theme	cellulosic	603:612	arg1	CS-PDMS					628:634	d-AgNWs@CS-PDMS	620:634	d-AgNWs@CS-PDMS	620:634	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	2	67	theme	cellulosic	603:612	arg1	film					614:617	cellulosic film	603:617	cellulosic film (d-AgNWs@CS-PDMS)	603:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	6	68	theme	wearable	1600:1607	arg1	devices					1609:1615	wearable devices	1600:1615	wearable devices	1600:1615	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	1	69	theme	interference	180:191	arg1	films					209:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	4	70	theme	mechanical	1034:1043	arg1	properties					1045:1054	striking mechanical properties	1025:1054	striking mechanical properties (maximum tensile strength of 511.8 MPa)	1025:1094	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	6	71	theme	@	1519:1519	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	3	72	theme	conductive	656:665	arg1	result					736:741	a result	734:741	a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves	734:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	3	72	theme	conductive	656:665	arg1	pathway					667:673	The consecutively conductive pathway	638:673	The consecutively conductive pathway of AgNWs	638:682	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	3	73	theme	EM	852:853	arg1	waves					855:859	incident EM waves	843:859	incident EM waves	843:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	1	74	theme	interest	270:277	arg1	interest					270:277	interest	270:277	interest	270:277	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	1	74	theme	interest	270:277	arg1	lot					263:265	a lot	261:265	a lot of interest	261:277	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	6	75	theme	obtained	1503:1510	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	6	76	theme	composite	1528:1536	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	1	77	theme	EMI	194:196	arg1	films					209:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	multifunctional electromagnetic interference (EMI) shielding films	148:213	Constructing multifunctional electromagnetic interference (EMI) shielding films with superior mechanical strength has sparked a lot of interest in the fields of wearable electronics.					
35306804	3	78	theme	waves	855:859	arg1	reflection					829:838	the reflection	825:838	the reflection of incident EM waves	825:859	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	0	79	theme	Composite	76:84	arg1	Film					86:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film	0:89	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.	0:133	An Ultrastrong and Antibacterial Silver Nanowire/Aligned Cellulose Scaffold Composite Film for Electromagnetic Interference Shielding.					
35306804	3	80	theme	CS	728:729	arg1	microchannels					707:719	the microchannels	703:719	the microchannels of the CS	703:729	The consecutively conductive pathway of AgNWs was constructed in the microchannels of the CS as a result of the hydrogen bonding between AgNWs and cellulose fibers, which is conducive to the reflection of incident EM waves.					
35306804	6	81	theme	CS-PDMS	1520:1526	arg1	film					1538:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	the obtained d-AgNWs@CS-PDMS composite film	1499:1541	These results demonstrate that the obtained d-AgNWs@CS-PDMS composite film has high potential as an EMI shielding material used for wearable devices.					
35306804	2	82	theme	wood	467:470	arg1	delignification					472:486	wood delignification	467:486	wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS)	467:635	In this work, the conductive silver nanowires (AgNWs) were synthesized and impregnated into the highly aligned cellulose scaffold (CS) fabricated by wood delignification followed by hot-pressing and polydimethylsiloxane (PDMS) dipping processes to obtain the outstanding EMI shielding cellulosic film (d-AgNWs@CS-PDMS).					
35306804	4	83	theme	tensile	1065:1071	arg1	strength					1073:1080	maximum tensile strength	1057:1080	maximum tensile strength of 511.8 MPa	1057:1093	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
35306804	4	84	theme	hot	974:976	arg1	pressing					978:985	hot pressing	974:985	hot pressing	974:985	The higher degree of nanofiber alignment and the compact conductive network were improved by densification upon hot pressing, which endows the composite film with striking mechanical properties (maximum tensile strength of 511.8 MPa) and superb EMI shielding performance (shielding effectiveness value of 46 dB with a filler content of 21.6 wt %) at the X band (8.2-12.4 GHz).					
36428212	5	0	theme	dry	544:546	arg1	patches					572:578	dry, shelf-stable cellulose patches	544:578	dry, shelf-stable cellulose patches	544:578	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	1	1	theme	management	149:158	arg1	approaches					160:169	topical disease management approaches	133:169	topical disease management approaches	133:169	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	6	2	theme	tissue	659:664	arg1	hydration					674:682	tissue surface hydration	659:682	tissue surface hydration	659:682	The dry patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring and offers on-demand adhesion.					
36428212	8	3	theme	soft	931:934	arg1	tissues					944:950	soft mucosal tissues	931:950	soft mucosal tissues	931:950	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	9	4	theme	7 days	1009:1014	arg1	minimum					998:1004	a minimum	996:1004	a minimum of 7 days in aqueous environment	996:1037	The structural integrity is maintained for a minimum of 7 days in aqueous environment.					
36428212	2	5	theme	frequent	290:297	arg1	reapplication					299:311	frequent reapplication	290:311	frequent reapplication of the therapeutics	290:331	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	7	6	theme	patch	765:769	arg1	prototypes					771:780	The dry patch prototypes	757:780	The dry patch prototypes	757:780	The dry patch prototypes are optimized by controlling BC/adhesive mole ratios and dehydration technique.					
36428212	0	7	theme	Bacterial	0:8	arg1	patches					29:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches designed for soft mucosal interfaces.					
36428212	8	8	theme	adhesion	866:873	arg1	higher					887:892	higher	887:892	higher	887:892	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	8	8	theme	adhesion	866:873	arg1	strength					875:882	The adhesion strength	862:882	The adhesion strength	862:882	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	3	9	theme	bacterial	348:356	arg1	cellulose					358:366	bacterial cellulose	348:366	bacterial cellulose (BC)	348:371	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	9	theme	bacterial	348:356	arg1	BC					369:370	BC	369:370	BC	369:370	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	8	10	theme	denture	910:916	arg1	adhesives					918:926	commercial denture adhesives	899:926	commercial denture adhesives on soft mucosal tissues	899:950	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	2	11	from	adhesion	224:231	arg1	environment					268:278	such environment	263:278	such environment	263:278	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	3	12	theme	cellulose	358:366	arg1	Composites					334:343	Composites	334:343	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt	334:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	12	theme	cellulose	358:366	arg1	cellulose					358:366	bacterial cellulose	348:366	bacterial cellulose (BC)	348:371	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	12	theme	cellulose	358:366	arg1	attempt					404:410	carbene-based bioadhesives attempt	377:410	carbene-based bioadhesives attempt	377:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	1	13	theme	wet	79:81	arg1	environment					83:93	The wet environment	75:93	The wet environment in the oral cavity	75:112	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	2	14	from	retention	243:251	arg1	environment					268:278	such environment	263:278	such environment	263:278	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	9	15	theme	aqueous	1019:1025	arg1	environment					1027:1037	aqueous environment	1019:1037	aqueous environment	1019:1037	The structural integrity is maintained for a minimum of 7 days in aqueous environment.					
36428212	0	16	theme	cellulose	10:18	arg1	patches					29:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches designed for soft mucosal interfaces.					
36428212	5	17	theme	convenient	584:593	arg1	application					608:618	convenient ready-to-use application	584:618	convenient ready-to-use application	584:618	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	5	18	theme	first	523:527	arg1	time					529:532	the first time	519:532	the first time	519:532	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	3	19	theme	bioadhesives	391:402	arg1	attempt					404:410	carbene-based bioadhesives attempt	377:410	carbene-based bioadhesives attempt	377:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	5	20	theme	ready-to-use	595:606	arg1	application					608:618	convenient ready-to-use application	584:618	convenient ready-to-use application	584:618	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	9	21	from	minimum	998:1004	arg1	environment					1027:1037	aqueous environment	1019:1037	aqueous environment	1019:1037	The structural integrity is maintained for a minimum of 7 days in aqueous environment.					
36428212	6	22	theme	on-demand	737:745	arg1	adhesion					747:754	on-demand adhesion	737:754	on-demand adhesion	737:754	The dry patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring and offers on-demand adhesion.					
36428212	7	23	theme	dry	761:763	arg1	prototypes					771:780	The dry patch prototypes	757:780	The dry patch prototypes	757:780	The dry patch prototypes are optimized by controlling BC/adhesive mole ratios and dehydration technique.					
36428212	8	24	from	adhesives	918:926	arg1	tissues					944:950	soft mucosal tissues	931:950	soft mucosal tissues	931:950	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	5	25	dep	dry	544:546	arg1	shelf-stable					549:560	shelf-stable	549:560	shelf-stable	549:560	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	11	26	theme	BC-based	1183:1190	arg1	patches					1201:1207	BC-based adhesive patches	1183:1207	BC-based adhesive patches	1183:1207	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	0	27	theme	adhesive	20:27	arg1	patches					29:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches	0:35	Bacterial cellulose adhesive patches designed for soft mucosal interfaces.					
36428212	2	28	theme	material	188:195	arg1	properties					197:206	The compromised material properties	172:206	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment	172:278	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	1	29	theme	oral	102:105	arg1	cavity					107:112	the oral cavity	98:112	the oral cavity	98:112	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	5	30	theme	current	499:505	arg1	design					507:512	The current design	495:512	The current design	495:512	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	11	31	theme	adhesive	1192:1199	arg1	patches					1201:1207	BC-based adhesive patches	1183:1207	BC-based adhesive patches	1183:1207	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	8	32	theme	mucosal	936:942	arg1	tissues					944:950	soft mucosal tissues	931:950	soft mucosal tissues	931:950	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	2	33	theme	compromised	176:186	arg1	properties					197:206	The compromised material properties	172:206	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment	172:278	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	7	34	theme	dehydration	839:849	arg1	technique					851:859	dehydration technique	839:859	dehydration technique	839:859	The dry patch prototypes are optimized by controlling BC/adhesive mole ratios and dehydration technique.					
36428212	11	35	theme	drug	1253:1256	arg1	depots					1258:1263	drug depots	1253:1263	drug depots	1253:1263	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	2	36	theme	short	237:241	arg1	retention					243:251	short retention	237:251	short retention	237:251	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	0	37	theme	mucosal	55:61	arg1	interfaces					63:72	soft mucosal interfaces	50:72	soft mucosal interfaces	50:72	Bacterial cellulose adhesive patches designed for soft mucosal interfaces.					
36428212	9	38	theme	structural	957:966	arg1	integrity					968:976	The structural integrity	953:976	The structural integrity	953:976	The structural integrity is maintained for a minimum of 7 days in aqueous environment.					
36428212	4	39	theme	aqueous	473:479	arg1	formulations					481:492	aqueous formulations	473:492	aqueous formulations	473:492	Previous designs comprised of aqueous formulations.					
36428212	11	40	theme	patches	1201:1207	arg1	platform					1223:1230	a flexible platform	1212:1230	a flexible platform for wound dressings, drug depots, or combination thereof	1212:1287	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	11	40	theme	patches	1201:1207	arg1	application					1168:1178	the application	1164:1178	the application of BC-based adhesive patches	1164:1207	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	8	41	theme	commercial	899:908	arg1	adhesives					918:926	commercial denture adhesives	899:926	commercial denture adhesives on soft mucosal tissues	899:950	The adhesion strength is higher than commercial denture adhesives on soft mucosal tissues.					
36428212	0	42	theme	soft	50:53	arg1	interfaces					63:72	soft mucosal interfaces	50:72	soft mucosal interfaces	50:72	Bacterial cellulose adhesive patches designed for soft mucosal interfaces.					
36428212	2	43	theme	weak	219:222	arg1	<8 h					254:257	<8 h	254:257	<8 h	254:257	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	2	43	theme	weak	219:222	arg1	adhesion					224:231	weak adhesion	219:231	weak adhesion	219:231	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	5	44	theme	cellulose	562:570	arg1	patches					572:578	dry, shelf-stable cellulose patches	544:578	dry, shelf-stable cellulose patches	544:578	The current design, for the first time, presents dry, shelf-stable cellulose patches for convenient ready-to-use application.					
36428212	6	45	theme	carbene-based	700:712	arg1	photocuring					714:724	carbene-based photocuring	700:724	carbene-based photocuring	700:724	The dry patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring and offers on-demand adhesion.					
36428212	6	46	dep	patches	629:635	arg1	remove					652:657	remove	652:657	patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring	629:724	The dry patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring and offers on-demand adhesion.					
36428212	10	47	theme	proteins	1134:1141	arg1	permeation					1120:1129	permeation	1120:1129	permeation of proteins	1120:1141	The patches act as selective nanoporous barrier against bacteria while allowing permeation of proteins.					
36428212	11	48	theme	wound	1236:1240	arg1	dressings					1242:1250	wound dressings	1236:1250	wound dressings	1236:1250	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	11	49	theme	flexible	1214:1221	arg1	application					1168:1178	the application	1164:1178	the application of BC-based adhesive patches	1164:1207	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	11	49	theme	flexible	1214:1221	arg1	platform					1223:1230	a flexible platform	1212:1230	a flexible platform for wound dressings, drug depots, or combination thereof	1212:1287	The results support the application of BC-based adhesive patches as a flexible platform for wound dressings, drug depots, or combination thereof.					
36428212	7	50	theme	BC/adhesive	811:821	arg1	ratios					828:833	BC/adhesive mole ratios	811:833	BC/adhesive mole ratios	811:833	The dry patch prototypes are optimized by controlling BC/adhesive mole ratios and dehydration technique.					
36428212	2	51	theme	such	263:266	arg1	environment					268:278	such environment	263:278	such environment	263:278	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	10	52	theme	nanoporous	1069:1078	arg1	barrier					1080:1086	selective nanoporous barrier	1059:1086	selective nanoporous barrier against bacteria	1059:1103	The patches act as selective nanoporous barrier against bacteria while allowing permeation of proteins.					
36428212	2	53	theme	therapeutics	320:331	arg1	reapplication					299:311	frequent reapplication	290:311	frequent reapplication of the therapeutics	290:331	The compromised material properties leading to weak adhesion and short retention (<8 h) in such environment result in frequent reapplication of the therapeutics.					
36428212	1	54	from	environment	83:93	arg1	cavity					107:112	the oral cavity	98:112	the oral cavity	98:112	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	7	55	theme	mole	823:826	arg1	ratios					828:833	BC/adhesive mole ratios	811:833	BC/adhesive mole ratios	811:833	The dry patch prototypes are optimized by controlling BC/adhesive mole ratios and dehydration technique.					
36428212	4	56	theme	Previous	443:450	arg1	designs					452:458	Previous designs	443:458	Previous designs	443:458	Previous designs comprised of aqueous formulations.					
36428212	10	57	theme	selective	1059:1067	arg1	barrier					1080:1086	selective nanoporous barrier	1059:1086	selective nanoporous barrier against bacteria	1059:1103	The patches act as selective nanoporous barrier against bacteria while allowing permeation of proteins.					
36428212	1	58	theme	topical	133:139	arg1	approaches					160:169	topical disease management approaches	133:169	topical disease management approaches	133:169	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	3	59	theme	carbene-based	377:389	arg1	attempt					404:410	carbene-based bioadhesives attempt	377:410	carbene-based bioadhesives attempt	377:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	60	theme	attempt	404:410	arg1	Composites					334:343	Composites	334:343	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt	334:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	60	theme	attempt	404:410	arg1	cellulose					358:366	bacterial cellulose	348:366	bacterial cellulose (BC)	348:371	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	3	60	theme	attempt	404:410	arg1	attempt					404:410	carbene-based bioadhesives attempt	377:410	carbene-based bioadhesives attempt	377:410	Composites of bacterial cellulose (BC) and carbene-based bioadhesives attempt to address these shortcomings.					
36428212	1	61	theme	disease	141:147	arg1	approaches					160:169	topical disease management approaches	133:169	topical disease management approaches	133:169	The wet environment in the oral cavity is challenging for topical disease management approaches.					
36428212	6	62	theme	surface	666:672	arg1	hydration					674:682	tissue surface hydration	659:682	tissue surface hydration	659:682	The dry patches simultaneously remove tissue surface hydration while retaining carbene-based photocuring and offers on-demand adhesion.					
36519335	0	0	theme	biofilm	98:104	arg1	inhibition					106:115	bacterial biofilm inhibition	88:115	bacterial biofilm inhibition	88:115	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	6	1	theme	biofilm	1058:1064	arg1	formation					1066:1074	biofilm formation	1058:1074	biofilm formation	1058:1074	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	1	2	from	rise	202:205	arg1	strains					231:237	antibiotic resistant strains	210:237	antibiotic resistant strains	210:237	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	1	3	theme	new	272:274	arg1	agents					290:295	new antibacterial agents	272:295	new antibacterial agents	272:295	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	0	4	theme	bacterial	88:96	arg1	inhibition					106:115	bacterial biofilm inhibition	88:115	bacterial biofilm inhibition	88:115	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	6	5	theme	biomass	1023:1029	arg1	inhibition					998:1007	87% inhibition	994:1007	87% inhibition of planktonic biomass	994:1029	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	6	5	theme	biomass	1023:1029	arg1	reduction					1045:1053	up to 74% reduction	1035:1053	up to 74% reduction in biofilm formation	1035:1074	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	6	6	dep	%	1043:1043	arg1	74					1041:1042	74	1041:1042	74	1041:1042	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	4	7	theme	Gram-positive	803:815	arg1	bacteria					841:848	planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria	708:848	bacteria	841:848	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	1	8	theme	antibacterial	276:288	arg1	agents					290:295	new antibacterial agents	272:295	new antibacterial agents	272:295	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	6	9	theme	planktonic	1012:1021	arg1	biomass					1023:1029	planktonic biomass	1012:1029	planktonic biomass	1012:1029	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	2	10	theme	bactericidal	316:327	arg1	hydrogels					329:337	composite bactericidal hydrogels	306:337	composite bactericidal hydrogels	306:337	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	3	11	theme	composite	624:632	arg1	hydrogels					634:642	composite hydrogels	624:642	composite hydrogels	624:642	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	2	12	theme	composite	306:314	arg1	hydrogels					329:337	composite bactericidal hydrogels	306:337	composite bactericidal hydrogels	306:337	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	4	13	theme	AgNT-hydrogel	675:687	arg1	activity					663:670	The antibacterial activity	645:670	The antibacterial activity of AgNT-hydrogel	645:687	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	7	14	theme	bacterial	1204:1212	arg1	infection					1214:1222	bacterial infection	1204:1222	bacterial infection	1204:1222	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	3	15	theme	robust	524:529	arg1	strength					542:549	robust mechanical strength	524:549	robust mechanical strength	524:549	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	16	theme	enzymatic	596:604	arg1	biodegradation					606:619	enzymatic biodegradation	596:619	enzymatic biodegradation	596:619	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	6	17	from	inhibition	998:1007	arg1	formation					1066:1074	biofilm formation	1058:1074	biofilm formation	1058:1074	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	6	18	theme	%	996:996	arg1	inhibition					998:1007	87% inhibition	994:1007	87% inhibition of planktonic biomass	994:1029	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	7	19	theme	infection	1214:1222	arg1	forms					1195:1199	various forms	1187:1199	various forms of bacterial infection	1187:1222	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	2	20	theme	hydrogels	475:483	arg1	network					425:431	a hybrid polymer network	408:431	a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	408:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	0	21	theme	gum	7:9	arg1	hydrogel					38:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	6	22	theme	87	994:995	arg1	%					996:996	%	996:996	%	996:996	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	4	23	dep	bacteria	841:848	arg1	aureus					833:838	Staphylococcus aureus	818:838	Staphylococcus aureus	818:838	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	2	24	theme	polymer	417:423	arg1	network					425:431	a hybrid polymer network	408:431	a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	408:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	0	25	theme	Hybrid	0:5	arg1	hydrogel					38:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	2	26	theme	hybrid	410:415	arg1	network					425:431	a hybrid polymer network	408:431	a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	408:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	0	27	theme	alginate	29:36	arg1	hydrogel					38:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	1	28	theme	Biomaterial	118:128	arg1	infections					151:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	1	29	theme	resistant	221:229	arg1	strains					231:237	antibiotic resistant strains	210:237	antibiotic resistant strains	210:237	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	2	30	theme	GT/SA	468:472	arg1	hydrogels					475:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	4	31	theme	antibacterial	649:661	arg1	activity					663:670	The antibacterial activity	645:670	The antibacterial activity of AgNT-hydrogel	645:687	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	7	32	theme	various	1187:1193	arg1	forms					1195:1199	various forms	1187:1199	various forms of bacterial infection	1187:1222	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	6	33	dep	74	1041:1042	arg1	to					1038:1039	to	1038:1039	to	1038:1039	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	1	34	theme	associated	130:139	arg1	infections					151:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	2	35	theme	Alginate	458:465	arg1	hydrogels					475:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	3	36	theme	Physico-chemical	486:501	arg1	examination					503:513	Physico-chemical examination	486:513	Physico-chemical examination	486:513	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	1	37	theme	antibiotic	210:219	arg1	strains					231:237	antibiotic resistant strains	210:237	antibiotic resistant strains	210:237	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	2	38	theme	Tragacanth/Sodium	440:456	arg1	hydrogels					475:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	5	39	theme	dose-dependent	895:908	arg1	decrease					910:917	a dose-dependent decrease	893:917	a dose-dependent decrease in bacterial growth	893:937	For all the strains, AgNT-hydrogel showed a dose-dependent decrease in bacterial growth.					
36519335	6	40	dep	reduction	1045:1053	arg1	%					1043:1043	%	1043:1043	%	1043:1043	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	7	41	theme	promising	1108:1116	arg1	approach					1118:1125	a promising approach	1106:1125	a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection	1106:1222	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	2	42	theme	Gum	436:438	arg1	hydrogels					475:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	436:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	0	43	theme	silver	63:68	arg1	nanotriangles					70:82	silver nanotriangles	63:82	silver nanotriangles for bacterial biofilm inhibition	63:115	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	7	44	theme	antibacterial	1141:1153	arg1	hydrogels					1165:1173	antibacterial composite hydrogels	1141:1173	antibacterial composite hydrogels	1141:1173	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	6	45	theme	40-80 mg	972:979	arg1	AgNT-hydrogels					956:969	AgNT-hydrogels	956:969	AgNT-hydrogels (40-80 mg ml-1)	956:985	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	6	45	theme	40-80 mg	972:979	arg1	ml-1					981:984	40-80 mg ml-1	972:984	40-80 mg ml-1	972:984	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	4	46	dep	Gram-negative	739:751	arg1	coli					766:769	Escherichia coli	754:769	Escherichia coli	754:769	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	4	46	dep	Gram-negative	739:751	arg1	aeruginosa					787:796	Pseudomonas aeruginosa	775:796	Pseudomonas aeruginosa	775:796	The antibacterial activity of AgNT-hydrogel was tested against planktonic and biofilm-forming Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.					
36519335	1	47	theme	bacterial	141:149	arg1	infections					151:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections	118:160	Biomaterial associated bacterial infections are indomitable to treatment due to the rise in antibiotic resistant strains, thereby triggering the need for new antibacterial agents.					
36519335	7	48	theme	composite	1155:1163	arg1	hydrogels					1165:1173	antibacterial composite hydrogels	1141:1173	antibacterial composite hydrogels	1141:1173	Overall, this study proposes a promising approach for designing antibacterial composite hydrogels to mitigate various forms of bacterial infection.					
36519335	3	49	theme	appreciable	552:562	arg1	porosity					564:571	appreciable porosity	552:571	appreciable porosity	552:571	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	6	50	from	reduction	1045:1053	arg1	formation					1066:1074	biofilm formation	1058:1074	biofilm formation	1058:1074	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	6	51	theme	AgNT-hydrogels	956:969	arg1	addition					944:951	The addition	940:951	The addition of AgNT-hydrogels (40-80 mg ml-1)	940:985	The addition of AgNT-hydrogels (40-80 mg ml-1) caused 87% inhibition of planktonic biomass and up to 74% reduction in biofilm formation.					
36519335	2	52	theme	silver	372:377	arg1	nanotriangles					379:391	silver nanotriangles	372:391	silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels	372:483	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	2	52	theme	silver	372:377	arg1	AgNTs					394:398	AgNTs	394:398	AgNTs	394:398	Herein, composite bactericidal hydrogels were formulated by incorporating silver nanotriangles (AgNTs) inside a hybrid polymer network of Gum Tragacanth/Sodium Alginate (GT/SA) hydrogels.					
36519335	3	53	theme	hydrogels	634:642	arg1	strength					542:549	robust mechanical strength	524:549	robust mechanical strength	524:549	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	53	theme	hydrogels	634:642	arg1	porosity					564:571	appreciable porosity	552:571	appreciable porosity	552:571	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	53	theme	hydrogels	634:642	arg1	in vitro					587:594	desirable in vitro	577:594	desirable in vitro	577:594	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	54	theme	mechanical	531:540	arg1	strength					542:549	robust mechanical strength	524:549	robust mechanical strength	524:549	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	55	theme	desirable	577:585	arg1	in vitro					587:594	desirable in vitro	577:594	desirable in vitro	577:594	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	3	56	dep	strength	542:549	arg1	biodegradation					606:619	enzymatic biodegradation	596:619	enzymatic biodegradation	596:619	Physico-chemical examination revealed robust mechanical strength, appreciable porosity and desirable in vitro enzymatic biodegradation of composite hydrogels.					
36519335	5	57	from	decrease	910:917	arg1	growth					932:937	bacterial growth	922:937	bacterial growth	922:937	For all the strains, AgNT-hydrogel showed a dose-dependent decrease in bacterial growth.					
36519335	0	58	theme	tragacanth/sodium	11:27	arg1	hydrogel					38:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel	0:45	Hybrid gum tragacanth/sodium alginate hydrogel reinforced with silver nanotriangles for bacterial biofilm inhibition.					
36519335	5	59	theme	bacterial	922:930	arg1	growth					932:937	bacterial growth	922:937	bacterial growth	922:937	For all the strains, AgNT-hydrogel showed a dose-dependent decrease in bacterial growth.					
34995656	5	0	theme	adsorption	792:801	arg1	capacity					803:810	The adsorption capacity	788:810	The adsorption capacity of MB	788:816	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	7	1	theme	isotherm	1220:1227	arg1	model					1229:1233	Langmuir isotherm model	1211:1233	Langmuir isotherm model	1211:1233	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	9	2	theme	water	1399:1403	arg1	treatment					1405:1413	water treatment	1399:1413	water treatment	1399:1413	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	4	3	theme	blue	738:741	arg1	dye					748:750	methylene blue (MB) dye	728:750	methylene blue (MB) dye	728:750	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	7	4	theme	pseudo-second	1132:1144	arg1	model					1152:1156	a pseudo-second order model	1130:1156	a pseudo-second order model	1130:1156	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	1	5	theme	sustainable	163:173	arg1	resource					175:182	a sustainable resource	161:182	a sustainable resource for water treatment	161:202	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	1	5	theme	sustainable	163:173	arg1	biomass					150:156	marine biomass	143:156	marine biomass	143:156	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	4	6	theme	concentrated	757:768	arg1	solution					778:785	concentrated aqueous solution	757:785	concentrated aqueous solution	757:785	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	4	7	dep	blue	738:741	arg1	MB					744:745	MB	744:745	MB	744:745	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	3	8	theme	high	576:579	arg1	ratio					590:594	a high swelling ratio	574:594	a high swelling ratio	574:594	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	4	9	theme	spongy-like	613:623	arg1	material					643:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	2	10	dep	macroalgae	318:327	arg1	tomentosum					337:346	Codium tomentosum	330:346	Codium tomentosum	330:346	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	5	11	theme	batch	923:927	arg1	system					929:934	a controlled batch system	910:934	a controlled batch system	910:934	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	1	12	theme	marine	143:148	arg1	resource					175:182	a sustainable resource	161:182	a sustainable resource for water treatment	161:202	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	1	12	theme	marine	143:148	arg1	biomass					150:156	marine biomass	143:156	marine biomass	143:156	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	3	13	theme	cellulose	478:486	arg1	hydrogel					488:495	cellulose hydrogel	478:495	cellulose hydrogel using freeze-drying process	478:523	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	3	14	theme	cellulose	441:449	arg1	monolith					451:458	Macroporous cellulose monolith	429:458	Macroporous cellulose monolith	429:458	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	4	15	theme	as-produced	601:611	arg1	material					643:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	9	16	theme	produced	1326:1333	arg1	monolith					1345:1352	the produced cellulose monolith	1322:1352	the produced cellulose monolith	1322:1352	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	9	16	theme	produced	1326:1333	arg1	sustainable					1373:1383	a sustainable	1371:1383	a sustainable adsorbent for water treatment	1371:1413	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	3	17	theme	rigid	554:558	arg1	monolith					560:567	a mechanically rigid monolith	539:567	a mechanically rigid monolith with a high swelling ratio	539:594	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	4	18	theme	wastewater	680:689	arg1	treatment					691:699	wastewater treatment	680:699	wastewater treatment	680:699	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	9	19	theme	cellulose	1335:1343	arg1	monolith					1345:1352	the produced cellulose monolith	1322:1352	the produced cellulose monolith	1322:1352	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	9	19	theme	cellulose	1335:1343	arg1	sustainable					1373:1383	a sustainable	1371:1383	a sustainable adsorbent for water treatment	1371:1413	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	3	20	theme	swelling	581:588	arg1	ratio					590:594	a high swelling ratio	574:594	a high swelling ratio	574:594	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	1	21	theme	water	188:192	arg1	treatment					194:202	water treatment	188:202	water treatment	188:202	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	6	22	theme	adsorption	985:994	arg1	equilibrium					996:1006	the adsorption equilibrium	981:1006	the adsorption equilibrium	981:1006	From the kinetic studies, it was found that the adsorption equilibrium was reached within 660 min.					
34995656	8	23	theme	adsorption	1248:1257	arg1	capacity					1259:1266	The maximum adsorption capacity	1236:1266	The maximum adsorption capacity	1236:1266	The maximum adsorption capacity was found to be 454 mg/g.					
34995656	8	23	theme	adsorption	1248:1257	arg1	454 mg/g					1284:1291	454 mg/g	1284:1291	454 mg/g	1284:1291	The maximum adsorption capacity was found to be 454 mg/g.					
34995656	7	24	theme	kinetics	1080:1087	arg1	analysis					1053:1060	the analysis	1049:1060	the analysis of the adsorption kinetics	1049:1087	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	2	25	theme	foam	369:372	arg1	production					374:383	cellulose-based foam production	353:383	cellulose-based foam production	353:383	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	0	26	theme	cellulose	29:37	arg1	Manufacturing					0:12	Manufacturing	0:12	Manufacturing of macroporous cellulose	0:37	Manufacturing of macroporous cellulose monolith from green macroalgae and its application for wastewater treatment.					
34995656	2	27	theme	possible	296:303	arg1	use					305:307	the possible use	292:307	the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production	292:383	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	0	28	theme	macroporous	17:27	arg1	cellulose					29:37	macroporous cellulose	17:37	macroporous cellulose	17:37	Manufacturing of macroporous cellulose monolith from green macroalgae and its application for wastewater treatment.					
34995656	4	29	theme	porous	625:630	arg1	material					643:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	1	30	theme	Enormous	116:123	arg1	interest					125:132	Enormous interest	116:132	Enormous interest in using marine biomass as a sustainable resource for water treatment	116:202	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	2	31	theme	convenient	409:418	arg1	process					420:426	a versatile and convenient process	393:426	a versatile and convenient process	393:426	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	9	32	used	used	1363:1366	arg2	monolith					1345:1352	the produced cellulose monolith	1322:1352	the produced cellulose monolith	1322:1352	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	9	32	used	used	1363:1366	arg2	sustainable					1373:1383	a sustainable	1371:1383	a sustainable adsorbent for water treatment	1371:1413	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	7	33	theme	adsorption	1069:1078	arg1	kinetics					1080:1087	the adsorption kinetics	1065:1087	the adsorption kinetics	1065:1087	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	3	34	theme	Macroporous	429:439	arg1	monolith					451:458	Macroporous cellulose monolith	429:458	Macroporous cellulose monolith	429:458	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	5	35	theme	adsorption	862:871	arg1	parameters					881:890	adsorption process parameters	862:890	adsorption process parameters	862:890	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	5	36	theme	parameters	881:890	arg1	effect					852:857	the effect	848:857	the effect of adsorption process parameters	848:890	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	5	37	theme	MB	815:816	arg1	capacity					803:810	The adsorption capacity	788:810	The adsorption capacity of MB	788:816	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	2	38	theme	versatile	395:403	arg1	process					420:426	a versatile and convenient process	393:426	a versatile and convenient process	393:426	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	3	39	with	monolith	560:567	arg1	ratio					590:594	a high swelling ratio	574:594	a high swelling ratio	574:594	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	3	40	theme	freeze-drying	503:515	arg1	process					517:523	freeze-drying process	503:523	freeze-drying process	503:523	Macroporous cellulose monolith was prepared from cellulose hydrogel using freeze-drying process, resulting in a mechanically rigid monolith with a high swelling ratio.					
34995656	0	41	theme	green	53:57	arg1	macroalgae					59:68	green macroalgae	53:68	green macroalgae	53:68	Manufacturing of macroporous cellulose monolith from green macroalgae and its application for wastewater treatment.					
34995656	7	42	theme	Langmuir	1211:1218	arg1	model					1229:1233	Langmuir isotherm model	1211:1233	Langmuir isotherm model	1211:1233	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	9	43	theme	adsorbent	1385:1393	arg1	monolith					1345:1352	the produced cellulose monolith	1322:1352	the produced cellulose monolith	1322:1352	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	9	43	theme	adsorbent	1385:1393	arg1	sustainable					1373:1383	a sustainable	1371:1383	a sustainable adsorbent for water treatment	1371:1413	The findings suggested that the produced cellulose monolith could be used as a sustainable adsorbent for water treatment.					
34995656	2	44	theme	macroalgae	318:327	arg1	use					305:307	the possible use	292:307	the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production	292:383	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	4	45	theme	cellulosic	632:641	arg1	material					643:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	4	46	theme	aqueous	770:776	arg1	solution					778:785	concentrated aqueous solution	757:785	concentrated aqueous solution	757:785	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	2	47	theme	green	312:316	arg1	macroalgae					318:327	green macroalgae	312:327	green macroalgae (Codium tomentosum)	312:347	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	1	48	theme	past	233:236	arg1	decades					242:248	the past few decades	229:248	the past few decades	229:248	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	5	49	theme	process	873:879	arg1	parameters					881:890	adsorption process parameters	862:890	adsorption process parameters	862:890	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	2	50	theme	cellulose-based	353:367	arg1	production					374:383	cellulose-based foam production	353:383	cellulose-based foam production	353:383	Herein, the objective was to investigate the possible use of green macroalgae (Codium tomentosum) for cellulose-based foam production through a versatile and convenient process.					
34995656	8	51	theme	maximum	1240:1246	arg1	capacity					1259:1266	The maximum adsorption capacity	1236:1266	The maximum adsorption capacity	1236:1266	The maximum adsorption capacity was found to be 454 mg/g.					
34995656	8	51	theme	maximum	1240:1246	arg1	454 mg/g					1284:1291	454 mg/g	1284:1291	454 mg/g	1284:1291	The maximum adsorption capacity was found to be 454 mg/g.					
34995656	1	52	theme	few	238:240	arg1	decades					242:248	the past few decades	229:248	the past few decades	229:248	Enormous interest in using marine biomass as a sustainable resource for water treatment has been manifested over the past few decades.					
34995656	7	53	theme	order	1146:1150	arg1	model					1152:1156	a pseudo-second order model	1130:1156	a pseudo-second order model	1130:1156	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	6	54	theme	kinetic	946:952	arg1	studies					954:960	the kinetic studies	942:960	the kinetic studies	942:960	From the kinetic studies, it was found that the adsorption equilibrium was reached within 660 min.					
34995656	7	55	theme	adsorption	1169:1178	arg1	isotherm					1180:1187	the adsorption isotherm	1165:1187	the adsorption isotherm	1165:1187	Furthermore, the analysis of the adsorption kinetics reveals that the data could be fitted by a pseudo-second order model, while the adsorption isotherm could be described by Langmuir isotherm model.					
34995656	4	56	used	used	656:659	arg2	material					643:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material	597:650	The as-produced spongy-like porous cellulosic material was used as bio-sorbent for wastewater treatment, particularly for removing methylene blue (MB) dye from concentrated aqueous solution.					
34995656	5	57	theme	controlled	912:921	arg1	system					929:934	a controlled batch system	910:934	a controlled batch system	910:934	The adsorption capacity of MB was subsequently studied, and the effect of adsorption process parameters was determined in a controlled batch system.					
34995656	0	58	theme	wastewater	94:103	arg1	treatment					105:113	wastewater treatment	94:113	wastewater treatment	94:113	Manufacturing of macroporous cellulose monolith from green macroalgae and its application for wastewater treatment.					
36184184	4	0	theme	spectroscopy	560:571	arg1	analyses					573:580	spectroscopy analyses	560:580	spectroscopy analyses	560:580	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	7	1	theme	developed	1050:1058	arg1	films					1074:1078	the developed nanocomposite films	1046:1078	the developed nanocomposite films	1046:1078	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	1	2	theme	food	280:283	arg1	preservation					285:296	food preservation	280:296	food preservation	280:296	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	0	3	theme	carp	93:96	arg1	preservation					98:109	silver carp preservation	86:109	silver carp preservation	86:109	Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation.					
36184184	4	4	theme	high	592:595	arg1	compatibility					597:609	high compatibility	592:609	high compatibility between the CS-TP-lip and film matrix through intermolecular interactions	592:683	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	1	5	theme	tea	193:195	arg1	CS-TP-lip					246:254	CS-TP-lip	246:254	CS-TP-lip	246:254	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	5	theme	tea	193:195	arg1	nanoliposomes					231:243	tea polyphenol-loaded chitosan coated nanoliposomes	193:243	tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	193:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	2	6	theme	composite	365:373	arg1	films					375:379	composite films	365:379	composite films	365:379	The effects of the CS-TP-lip on the physicochemical properties of composite films were systematically evaluated.					
36184184	7	7	theme	food	1176:1179	arg1	preservation					1181:1192	food preservation	1176:1192	food preservation	1176:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	2	8	theme	CS-TP-lip	318:326	arg1	effects					303:309	The effects	299:309	The effects of the CS-TP-lip on the physicochemical properties of composite films	299:379	The effects of the CS-TP-lip on the physicochemical properties of composite films were systematically evaluated.					
36184184	6	9	used	used	977:980	arg2	materials					995:1003	packaging materials	985:1003	packaging materials for fish fillet preservation	985:1032	The films were successfully used as packaging materials for fish fillet preservation.					
36184184	6	9	used	used	977:980	arg2	films					953:957	The films	949:957	The films	949:957	The films were successfully used as packaging materials for fish fillet preservation.					
36184184	7	10	theme	film	1167:1170	arg1	generation					1111:1120	a new generation	1105:1120	a new generation of biodegradable, sustainable, and bioactive film for food preservation	1105:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	10	theme	film	1167:1170	arg1	promise					1094:1100	great promise	1088:1100	great promise	1088:1100	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	5	11	theme	functioning	931:941	arg1	time					943:946	its functioning time	927:946	its functioning time	927:946	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	1	12	theme	polyphenol-loaded	197:213	arg1	CS-TP-lip					246:254	CS-TP-lip	246:254	CS-TP-lip	246:254	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	12	theme	polyphenol-loaded	197:213	arg1	nanoliposomes					231:243	tea polyphenol-loaded chitosan coated nanoliposomes	193:243	tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	193:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	3	13	theme	average	461:467	arg1	size					478:481	an average particle size	458:481	an average particle size of about 300 nm	458:497	The CS-TP-lip exhibited spherical shapes with an average particle size of about 300 nm.					
36184184	3	14	theme	300 nm	492:497	arg1	size					478:481	an average particle size	458:481	an average particle size of about 300 nm	458:497	The CS-TP-lip exhibited spherical shapes with an average particle size of about 300 nm.					
36184184	0	15	theme	cellulose	19:27	arg1	films					29:33	Chitosan/bacterial cellulose films	0:33	Chitosan/bacterial cellulose films incorporated with tea polyphenol	0:66	Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation.					
36184184	1	16	theme	coated	224:229	arg1	CS-TP-lip					246:254	CS-TP-lip	246:254	CS-TP-lip	246:254	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	16	theme	coated	224:229	arg1	nanoliposomes					231:243	tea polyphenol-loaded chitosan coated nanoliposomes	193:243	tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	193:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	0	17	theme	Chitosan/bacterial	0:17	arg1	films					29:33	Chitosan/bacterial cellulose films	0:33	Chitosan/bacterial cellulose films incorporated with tea polyphenol	0:66	Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation.					
36184184	4	18	theme	film	637:640	arg1	matrix					642:647	film matrix	637:647	film matrix	637:647	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	7	19	theme	bioactive	1157:1165	arg1	film					1167:1170	bioactive film	1157:1170	bioactive film	1157:1170	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	2	20	theme	physicochemical	335:349	arg1	properties					351:360	the physicochemical properties	331:360	the physicochemical properties of composite films	331:379	The effects of the CS-TP-lip on the physicochemical properties of composite films were systematically evaluated.					
36184184	5	21	theme	tea	882:884	arg1	polyphenol					886:895	tea polyphenol	882:895	tea polyphenol	882:895	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	4	22	dep	transform	541:549	arg1	infrared					551:558	infrared	551:558	transform infrared spectroscopy analyses	541:580	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	7	23	theme	sustainable	1140:1150	arg1	generation					1111:1120	a new generation	1105:1120	a new generation of biodegradable, sustainable, and bioactive film for food preservation	1105:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	23	theme	sustainable	1140:1150	arg1	promise					1094:1100	great promise	1088:1100	great promise	1088:1100	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	5	24	theme	polyphenol	886:895	arg1	stability					869:877	the stability	865:877	the stability of tea polyphenol	865:895	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	4	25	dep	Fourier	533:539	arg1	transform					541:549	transform	541:549	transform infrared spectroscopy analyses	541:580	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	5	26	theme	films	785:789	arg1	elongation					736:745	the elongation	732:745	the elongation at break and thermal stability of the films	732:789	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	4	27	theme	Scanning	500:507	arg1	microscopy					518:527	Scanning electron microscopy	500:527	Scanning electron microscopy	500:527	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	0	28	theme	tea	53:55	arg1	polyphenol					57:66	tea polyphenol	53:66	tea polyphenol	53:66	Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation.					
36184184	7	29	theme	biodegradable	1125:1137	arg1	generation					1111:1120	a new generation	1105:1120	a new generation of biodegradable, sustainable, and bioactive film for food preservation	1105:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	29	theme	biodegradable	1125:1137	arg1	promise					1094:1100	great promise	1088:1100	great promise	1088:1100	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	3	30	theme	particle	469:476	arg1	size					478:481	an average particle size	458:481	an average particle size of about 300 nm	458:497	The CS-TP-lip exhibited spherical shapes with an average particle size of about 300 nm.					
36184184	6	31	theme	fillet	1014:1019	arg1	preservation					1021:1032	fish fillet preservation	1009:1032	fish fillet preservation	1009:1032	The films were successfully used as packaging materials for fish fillet preservation.					
36184184	4	32	theme	intermolecular	657:670	arg1	interactions					672:683	intermolecular interactions	657:683	intermolecular interactions	657:683	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	5	33	from	break	750:754	arg1	elongation					736:745	the elongation	732:745	the elongation at break and thermal stability of the films	732:789	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	4	34	theme	electron	509:516	arg1	microscopy					518:527	Scanning electron microscopy	500:527	Scanning electron microscopy	500:527	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	5	35	theme	thermal	760:766	arg1	stability					768:776	thermal stability	760:776	thermal stability	760:776	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	2	36	theme	films	375:379	arg1	properties					351:360	the physicochemical properties	331:360	the physicochemical properties of composite films	331:379	The effects of the CS-TP-lip on the physicochemical properties of composite films were systematically evaluated.					
36184184	6	37	theme	packaging	985:993	arg1	films					953:957	The films	949:957	The films	949:957	The films were successfully used as packaging materials for fish fillet preservation.					
36184184	6	37	theme	packaging	985:993	arg1	materials					995:1003	packaging materials	985:1003	packaging materials for fish fillet preservation	985:1032	The films were successfully used as packaging materials for fish fillet preservation.					
36184184	7	38	theme	great	1088:1092	arg1	generation					1111:1120	a new generation	1105:1120	a new generation of biodegradable, sustainable, and bioactive film for food preservation	1105:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	38	theme	great	1088:1092	arg1	promise					1094:1100	great promise	1088:1100	great promise	1088:1100	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	1	39	theme	chitosan/bacterial	140:157	arg1	agent					270:274	an active agent	260:274	an active agent for food preservation	260:296	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	39	theme	chitosan/bacterial	140:157	arg1	films					175:179	chitosan/bacterial cellulose-based films	140:179	chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	140:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	2	40	from	effects	303:309	arg1	properties					351:360	the physicochemical properties	331:360	the physicochemical properties of composite films	331:379	The effects of the CS-TP-lip on the physicochemical properties of composite films were systematically evaluated.					
36184184	5	41	from	stability	768:776	arg1	elongation					736:745	the elongation	732:745	the elongation at break and thermal stability of the films	732:789	Furthermore, due to the CS-TP-lip's presence, the elongation at break and thermal stability of the films could be enhanced to reach 75.14 ± 1.2 % and 395.33 °C, respectively, and the stability of tea polyphenol could be increased to prolong its functioning time.					
36184184	7	42	theme	new	1107:1109	arg1	generation					1111:1120	a new generation	1105:1120	a new generation of biodegradable, sustainable, and bioactive film for food preservation	1105:1192	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	42	theme	new	1107:1109	arg1	promise					1094:1100	great promise	1088:1100	great promise	1088:1100	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	7	43	theme	nanocomposite	1060:1072	arg1	films					1074:1078	the developed nanocomposite films	1046:1078	the developed nanocomposite films	1046:1078	Therefore, the developed nanocomposite films exhibit great promise as a new generation of biodegradable, sustainable, and bioactive film for food preservation.					
36184184	1	44	theme	cellulose-based	159:173	arg1	agent					270:274	an active agent	260:274	an active agent for food preservation	260:296	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	44	theme	cellulose-based	159:173	arg1	films					175:179	chitosan/bacterial cellulose-based films	140:179	chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	140:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	45	theme	active	263:268	arg1	agent					270:274	an active agent	260:274	an active agent for food preservation	260:296	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	45	theme	active	263:268	arg1	films					175:179	chitosan/bacterial cellulose-based films	140:179	chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	140:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	0	46	theme	silver	86:91	arg1	carp					93:96	silver carp	86:96	silver carp preservation	86:109	Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation.					
36184184	1	47	theme	chitosan	215:222	arg1	CS-TP-lip					246:254	CS-TP-lip	246:254	CS-TP-lip	246:254	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	1	47	theme	chitosan	215:222	arg1	nanoliposomes					231:243	tea polyphenol-loaded chitosan coated nanoliposomes	193:243	tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip)	193:255	This study aimed to develop chitosan/bacterial cellulose-based films loaded with tea polyphenol-loaded chitosan coated nanoliposomes (CS-TP-lip) as an active agent for food preservation.					
36184184	4	48	dep	CS-TP-lip	623:631	arg1	the					619:621	the	619:621	the	619:621	Scanning electron microscopy and Fourier transform infrared spectroscopy analyses suggested high compatibility between the CS-TP-lip and film matrix through intermolecular interactions.					
36184184	3	49	theme	spherical	436:444	arg1	shapes					446:451	spherical shapes	436:451	spherical shapes	436:451	The CS-TP-lip exhibited spherical shapes with an average particle size of about 300 nm.					
36184184	6	50	theme	fish	1009:1012	arg1	preservation					1021:1032	fish fillet preservation	1009:1032	fish fillet preservation	1009:1032	The films were successfully used as packaging materials for fish fillet preservation.					
35771389	3	0	from	stages	489:494	arg1	grains					457:462	The grains	453:462	METHODS The grains at different development stages	445:494	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	9	1	theme	suggested	1404:1412	arg1	candidates					1470:1479	candidates	1470:1479	candidates for further functional study	1470:1508	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	9	1	theme	suggested	1404:1412	arg1	genes					1414:1418	The suggested genes	1400:1418	The suggested genes related to late grain development of maize	1400:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	6	2	theme	enrichment	859:868	arg1	analysis					870:877	The enrichment analysis	855:877	The enrichment analysis of common differentially expressed genes (proteins)	855:929	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	7	3	theme	carbohydrate	1067:1078	arg1	metabolism					1080:1089	carbohydrate metabolism	1067:1089	carbohydrate metabolism	1067:1089	The downregulated genes were mainly concentrated in carbohydrate metabolism and lipid metabolism, while the upregulated genes were mainly in response to stress.					
35771389	1	4	theme	grain	170:174	arg1	composition					176:186	grain composition	170:186	grain composition	170:186	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	8	5	theme	key	1221:1223	arg1	genes					1235:1239	many key candidate genes	1216:1239	many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize	1216:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	9	6	theme	late	1431:1434	arg1	development					1442:1452	late grain development	1431:1452	late grain development of maize	1431:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	1	7	theme	late	195:198	arg1	stage					200:204	the late stage	191:204	the late stage of grain development	191:225	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	8	8	theme	dehydrin	1242:1249	arg1	genes					1251:1255	dehydrin genes	1242:1255	dehydrin genes	1242:1255	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	7	9	theme	downregulated	1019:1031	arg1	genes					1033:1037	The downregulated genes	1015:1037	The downregulated genes	1015:1037	The downregulated genes were mainly concentrated in carbohydrate metabolism and lipid metabolism, while the upregulated genes were mainly in response to stress.					
35771389	5	10	theme	late	822:825	arg1	stage					827:831	the late stage	818:831	the late stage of grain development	818:852	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	6	11	theme	genes	914:918	arg1	analysis					870:877	The enrichment analysis	855:877	The enrichment analysis of common differentially expressed genes (proteins)	855:929	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	9	12	dep	CONCLUSIONS	1388:1398	arg1	candidates					1470:1479	candidates	1470:1479	candidates for further functional study	1470:1508	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	9	12	dep	CONCLUSIONS	1388:1398	arg1	genes					1414:1418	The suggested genes	1400:1418	The suggested genes related to late grain development of maize	1400:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	8	13	theme	sucrose	1286:1292	arg1	synthase					1294:1301	sucrose synthase	1286:1301	sucrose synthase	1286:1301	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	5	14	theme	sucrose	733:739	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	14	theme	sucrose	733:739	arg1	content					722:728	the content	718:728	the content of sucrose, starch and ABA	718:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	14	theme	sucrose	733:739	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	9	15	theme	functional	1493:1502	arg1	study					1504:1508	further functional study	1485:1508	further functional study	1485:1508	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	5	16	dep	RESULTS	679:685	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	16	dep	RESULTS	679:685	arg1	content					722:728	the content	718:728	the content of sucrose, starch and ABA	718:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	16	dep	RESULTS	679:685	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	2	17	from	lines	412:416	arg1	development					432:442	late grain development	421:442	late grain development	421:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	0	18	theme	grain	67:71	arg1	development					73:83	late grain development	62:83	late grain development	62:83	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	1	19	theme	content	158:164	arg1	change					139:144	the change	135:144	the change of moisture content and grain composition	135:186	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	2	20	from	development	432:442	arg1	traits					377:382	physiological traits	363:382	physiological traits of two typical maize inbred lines in late grain development	363:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	2	21	theme	grain	426:430	arg1	development					432:442	late grain development	421:442	late grain development	421:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	8	22	theme	related	1344:1350	arg1	genes					1235:1239	many key candidate genes	1216:1239	many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize	1216:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	2	23	theme	physiological	363:375	arg1	traits					377:382	physiological traits	363:382	physiological traits of two typical maize inbred lines in late grain development	363:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	0	24	theme	Physiological	0:12	arg1	analysis					24:31	Physiological and omics analysis	0:31	Physiological and omics analysis of maize inbred lines during late grain development.	0:84	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	8	25	theme	late	1355:1358	arg1	development					1366:1376	late grain development	1355:1376	late grain development of maize	1355:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	2	26	theme	inbred	405:410	arg1	lines					412:416	two typical maize inbred lines	387:416	two typical maize inbred lines in late grain development	387:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	0	27	theme	omics	18:22	arg1	analysis					24:31	Physiological and omics analysis	0:31	Physiological and omics analysis of maize inbred lines during late grain development.	0:84	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	4	28	theme	relevant	663:670	arg1	genes					672:676	relevant genes	663:676	relevant genes	663:676	Transcriptomic and proteomic analysis of the materials were performed to screen relevant genes.					
35771389	2	29	theme	typical	391:397	arg1	lines					412:416	two typical maize inbred lines	387:416	two typical maize inbred lines in late grain development	387:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	5	30	theme	ABA	753:755	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	30	theme	ABA	753:755	arg1	content					722:728	the content	718:728	the content of sucrose, starch and ABA	718:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	30	theme	ABA	753:755	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	7	31	theme	upregulated	1123:1133	arg1	genes					1135:1139	the upregulated genes	1119:1139	the upregulated genes	1119:1139	The downregulated genes were mainly concentrated in carbohydrate metabolism and lipid metabolism, while the upregulated genes were mainly in response to stress.					
35771389	8	32	theme	maize	1381:1385	arg1	development					1366:1376	late grain development	1355:1376	late grain development of maize	1355:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	2	33	theme	key	328:330	arg1	genes					332:336	the key genes	324:336	the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development	324:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	0	34	theme	inbred	42:47	arg1	lines					49:53	maize inbred lines	36:53	maize inbred lines	36:53	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	1	35	theme	grain	209:213	arg1	development					215:225	grain development	209:225	grain development	209:225	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	9	36	theme	related	1420:1426	arg1	candidates					1470:1479	candidates	1470:1479	candidates for further functional study	1470:1508	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	9	36	theme	related	1420:1426	arg1	genes					1414:1418	The suggested genes	1400:1418	The suggested genes related to late grain development of maize	1400:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	6	37	theme	expressed	904:912	arg1	proteins					921:928	proteins	921:928	proteins	921:928	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	6	37	theme	expressed	904:912	arg1	genes					914:918	common differentially expressed genes	882:918	common differentially expressed genes (proteins)	882:929	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	8	38	dep	genes	1251:1255	arg1	genes					1337:1341	related genes	1329:1341	related genes	1329:1341	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	4	39	theme	Transcriptomic	583:596	arg1	analysis					612:619	Transcriptomic and proteomic analysis	583:619	Transcriptomic and proteomic analysis of the materials	583:636	Transcriptomic and proteomic analysis of the materials were performed to screen relevant genes.					
35771389	7	40	theme	lipid	1095:1099	arg1	metabolism					1101:1110	lipid metabolism	1095:1110	lipid metabolism	1095:1110	The downregulated genes were mainly concentrated in carbohydrate metabolism and lipid metabolism, while the upregulated genes were mainly in response to stress.					
35771389	1	41	theme	maize	243:247	arg1	varieties					249:257	different maize varieties	233:257	different maize varieties	233:257	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	6	42	theme	common	882:887	arg1	proteins					921:928	proteins	921:928	proteins	921:928	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	6	42	theme	common	882:887	arg1	genes					914:918	common differentially expressed genes	882:918	common differentially expressed genes (proteins)	882:929	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	3	43	theme	different	467:475	arg1	stages					489:494	different development stages	467:494	different development stages	467:494	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	5	44	theme	grain	836:840	arg1	development					842:852	grain development	836:852	grain development	836:852	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	4	45	theme	materials	628:636	arg1	analysis					612:619	Transcriptomic and proteomic analysis	583:619	Transcriptomic and proteomic analysis of the materials	583:636	Transcriptomic and proteomic analysis of the materials were performed to screen relevant genes.					
35771389	5	46	theme	starch	742:747	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	46	theme	starch	742:747	arg1	content					722:728	the content	718:728	the content of sucrose, starch and ABA	718:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	46	theme	starch	742:747	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	3	47	theme	water	551:555	arg1	content					540:546	the content	536:546	the content of water, sucrose, starch and ABA	536:580	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	1	48	theme	composition	176:186	arg1	change					139:144	the change	135:144	the change of moisture content and grain composition	135:186	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	2	49	from	variation	350:358	arg1	traits					377:382	physiological traits	363:382	physiological traits of two typical maize inbred lines in late grain development	363:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	8	50	theme	many	1216:1219	arg1	genes					1235:1239	many key candidate genes	1216:1239	many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize	1216:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	9	51	theme	grain	1436:1440	arg1	development					1442:1452	late grain development	1431:1452	late grain development of maize	1431:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	4	52	theme	proteomic	602:610	arg1	analysis					612:619	Transcriptomic and proteomic analysis	583:619	Transcriptomic and proteomic analysis of the materials	583:636	Transcriptomic and proteomic analysis of the materials were performed to screen relevant genes.					
35771389	5	53	theme	grain	691:695	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	53	theme	grain	691:695	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	3	54	theme	starch	567:572	arg1	content					540:546	the content	536:546	the content of water, sucrose, starch and ABA	536:580	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	5	55	theme	development	842:852	arg1	stage					827:831	the late stage	818:831	the late stage of grain development	818:852	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	3	56	theme	sucrose	558:564	arg1	content					540:546	the content	536:546	the content of water, sucrose, starch and ABA	536:580	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	1	57	theme	significant	108:118	arg1	differences					120:130	significant differences	108:130	significant differences in the change of moisture content and grain composition	108:186	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	8	58	theme	pathogenesis-related	1258:1277	arg1	genes					1279:1283	pathogenesis-related genes	1258:1283	pathogenesis-related genes	1258:1283	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	0	59	theme	late	62:65	arg1	development					73:83	late grain development	62:83	late grain development	62:83	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	3	60	theme	ABA	578:580	arg1	content					540:546	the content	536:546	the content of water, sucrose, starch and ABA	536:580	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	9	61	theme	further	1485:1491	arg1	study					1504:1508	further functional study	1485:1508	further functional study	1485:1508	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	1	62	theme	moisture	149:156	arg1	content					158:164	moisture content	149:164	moisture content	149:164	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	1	63	dep	BACKGROUND	86:95	arg1	were					103:106	were	103:106	were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties	103:257	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	8	64	theme	secondary	1307:1315	arg1	metabolites					1317:1327	secondary metabolites	1307:1327	secondary metabolites	1307:1327	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	65	theme	candidate	1225:1233	arg1	genes					1235:1239	many key candidate genes	1216:1239	many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize	1216:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	66	dep	genes	1235:1239	arg1	genes					1251:1255	dehydrin genes	1242:1255	dehydrin genes	1242:1255	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	66	dep	genes	1235:1239	arg1	genes					1279:1283	pathogenesis-related genes	1258:1283	pathogenesis-related genes	1258:1283	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	66	dep	genes	1235:1239	arg1	synthase					1294:1301	sucrose synthase	1286:1301	sucrose synthase	1286:1301	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	66	dep	genes	1235:1239	arg1	metabolites					1317:1327	secondary metabolites	1307:1327	secondary metabolites	1307:1327	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	8	67	theme	related	1329:1335	arg1	genes					1337:1341	related genes	1329:1341	related genes	1329:1341	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	5	68	theme	significant	769:779	arg1	differences					781:791	significant differences	769:791	significant differences between two varieties in the late stage of grain development	769:852	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	69	from	differences	781:791	arg1	stage					827:831	the late stage	818:831	the late stage of grain development	818:852	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	2	70	theme	late	421:424	arg1	development					432:442	late grain development	421:442	late grain development	421:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	1	71	theme	regulation	268:277	arg1	mechanism					279:287	the regulation mechanism	264:287	the regulation mechanism	264:287	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	1	71	theme	regulation	268:277	arg1	clear					296:300	clear	296:300	clear	296:300	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	1	72	from	differences	120:130	arg1	change					139:144	the change	135:144	the change of moisture content and grain composition	135:186	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	2	73	theme	lines	412:416	arg1	traits					377:382	physiological traits	363:382	physiological traits of two typical maize inbred lines in late grain development	363:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	2	74	theme	maize	399:403	arg1	lines					412:416	two typical maize inbred lines	387:416	two typical maize inbred lines in late grain development	387:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	0	75	theme	maize	36:40	arg1	lines					49:53	maize inbred lines	36:53	maize inbred lines	36:53	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	6	76	theme	extracellular	993:1005	arg1	region					1007:1012	the extracellular region	989:1012	the extracellular region	989:1012	The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region.					
35771389	8	77	theme	grain	1360:1364	arg1	development					1366:1376	late grain development	1355:1376	late grain development of maize	1355:1385	Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize.					
35771389	0	78	theme	lines	49:53	arg1	analysis					24:31	Physiological and omics analysis	0:31	Physiological and omics analysis of maize inbred lines during late grain development.	0:84	Physiological and omics analysis of maize inbred lines during late grain development.					
35771389	5	79	theme	dehydration	697:707	arg1	rate					709:712	The grain dehydration rate	687:712	The grain dehydration rate	687:712	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	5	79	theme	dehydration	697:707	arg1	RESULTS					679:685	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA	679:755	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were	679:760	RESULTS The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development.					
35771389	3	80	theme	development	477:487	arg1	stages					489:494	different development stages	467:494	different development stages	467:494	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	2	81	from	traits	377:382	arg1	development					432:442	late grain development	421:442	late grain development	421:442	OBJECTIVE To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development.					
35771389	1	82	theme	development	215:225	arg1	stage					200:204	the late stage	191:204	the late stage of grain development	191:225	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
35771389	9	83	theme	maize	1457:1461	arg1	development					1442:1452	late grain development	1431:1452	late grain development of maize	1431:1461	CONCLUSIONS The suggested genes related to late grain development of maize can be candidates for further functional study.					
35771389	3	84	dep	METHODS	445:451	arg1	grains					457:462	The grains	453:462	METHODS The grains at different development stages	445:494	METHODS The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA.					
35771389	1	85	theme	different	233:241	arg1	varieties					249:257	different maize varieties	233:257	different maize varieties	233:257	BACKGROUND There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear.					
36057293	6	0	theme	scaffold	713:720	arg1	hydrophilicity					691:704	the surface hydrophilicity	679:704	the surface hydrophilicity of PCL scaffold	679:720	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	6	0	theme	scaffold	713:720	arg1	properties					749:758	the mechanical properties	734:758	the mechanical properties	734:758	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	7	1	theme	expression	881:890	arg1	upregulation					855:866	the upregulation	851:866	the upregulation of CD31 gene expression	851:890	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	0	2	theme	anticoagulation	92:106	arg1	promotion					108:116	anticoagulation promotion	92:116	anticoagulation promotion	92:116	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	8	3	theme	adhesion	977:984	arg1	inhibition					954:963	more effective inhibition	939:963	more effective inhibition of platelet adhesion and blood clotting	939:1003	It also showed more effective inhibition of platelet adhesion and blood clotting in vitro.					
36057293	4	4	theme	oxidation	553:561	arg1	polymerization					563:576	oxidation polymerization	553:576	oxidation polymerization	553:576	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	0	5	theme	vascular	121:128	arg1	scaffold					130:137	vascular scaffold	121:137	vascular scaffold	121:137	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	8	6	theme	platelet	968:975	arg1	adhesion					977:984	platelet adhesion	968:984	platelet adhesion	968:984	It also showed more effective inhibition of platelet adhesion and blood clotting in vitro.					
36057293	7	7	theme	CD31	871:874	arg1	expression					881:890	CD31 gene expression	871:890	CD31 gene expression	871:890	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	8	8	theme	blood	990:994	arg1	clotting					996:1003	blood clotting	990:1003	blood clotting	990:1003	It also showed more effective inhibition of platelet adhesion and blood clotting in vitro.					
36057293	6	9	theme	PCL	709:711	arg1	scaffold					713:720	PCL scaffold	709:720	PCL scaffold	709:720	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	2	10	theme	functional	316:325	arg1	coating					327:333	a functional coating	314:333	a functional coating based on hyaluronic acid (HA), dopamine (DA), and heparin	314:391	Herein, we developed a functional coating based on hyaluronic acid (HA), dopamine (DA), and heparin.					
36057293	9	11	theme	functional	1065:1074	arg1	coating					1076:1082	this functional coating	1060:1082	this functional coating	1060:1082	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	0	12	theme	scaffold	130:137	arg1	endothelialization					69:86	endothelialization	69:86	endothelialization	69:86	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	0	12	theme	scaffold	130:137	arg1	promotion					108:116	anticoagulation promotion	92:116	anticoagulation promotion	92:116	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	4	13	theme	HA	481:482	arg1	material					484:491	The DA-grafted HA material	466:491	The DA-grafted HA material	466:491	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	4	14	theme	DA-grafted	470:479	arg1	material					484:491	The DA-grafted HA material	466:491	The DA-grafted HA material	466:491	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	8	15	theme	clotting	996:1003	arg1	inhibition					954:963	more effective inhibition	939:963	more effective inhibition of platelet adhesion and blood clotting	939:1003	It also showed more effective inhibition of platelet adhesion and blood clotting in vitro.					
36057293	6	16	theme	surface	683:689	arg1	hydrophilicity					691:704	the surface hydrophilicity	679:704	the surface hydrophilicity of PCL scaffold	679:720	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	0	17	theme	Surface	0:6	arg1	modification					8:19	Surface modification	0:19	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.	0:138	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	4	18	theme	PCL	536:538	arg1	scaffold					540:547	fibrous PCL scaffold	528:547	fibrous PCL scaffold	528:547	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	9	19	theme	long-term	1220:1228	arg1	patency					1230:1236	the long-term patency	1216:1236	the long-term patency of vascular grafts	1216:1255	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	9	20	theme	great	1087:1091	arg1	potential					1093:1101	great potential	1087:1101	great potential	1087:1101	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	0	21	theme	hydrophilic	26:36	arg1	coating					57:63	hydrophilic and heparin-loaded coating	26:63	hydrophilic and heparin-loaded coating	26:63	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	4	22	theme	fibrous	528:534	arg1	scaffold					540:547	fibrous PCL scaffold	528:547	fibrous PCL scaffold	528:547	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	2	23	theme	hyaluronic	344:353	arg1	HA					361:362	HA	361:362	HA	361:362	Herein, we developed a functional coating based on hyaluronic acid (HA), dopamine (DA), and heparin.					
36057293	2	23	theme	hyaluronic	344:353	arg1	acid					355:358	hyaluronic acid	344:358	hyaluronic acid (HA)	344:363	Herein, we developed a functional coating based on hyaluronic acid (HA), dopamine (DA), and heparin.					
36057293	7	24	theme	angiogenesis	825:836	arg1	behavior					838:845	angiogenesis behavior	825:845	angiogenesis behavior	825:845	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	3	25	theme	HA	452:453	arg1	molecules					455:463	the HA molecules	448:463	the HA molecules	448:463	In the present study, dopamine was firstly grafted to the HA molecules.					
36057293	7	26	theme	coated	774:779	arg1	scaffold					781:788	the coated scaffold	770:788	the coated scaffold	770:788	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	7	27	theme	EC	804:805	arg1	proliferation					807:819	EC proliferation	804:819	EC proliferation	804:819	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	0	28	theme	heparin-loaded	42:55	arg1	coating					57:63	hydrophilic and heparin-loaded coating	26:63	hydrophilic and heparin-loaded coating	26:63	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	4	29	theme	scaffold	540:547	arg1	surface					517:523	the surface	513:523	the surface of fibrous PCL scaffold	513:547	The DA-grafted HA material was then applied to the surface of fibrous PCL scaffold via oxidation polymerization.					
36057293	9	30	theme	vascular	1241:1248	arg1	grafts					1250:1255	vascular grafts	1241:1255	vascular grafts	1241:1255	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	6	31	theme	composite	652:660	arg1	coating					662:668	The composite coating	648:668	The composite coating	648:668	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	1	32	theme	long-term	255:263	arg1	patency					265:271	long-term patency	255:271	long-term patency of vascular grafts	255:290	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	9	33	theme	grafts	1250:1255	arg1	patency					1230:1236	the long-term patency	1216:1236	the long-term patency of vascular grafts	1216:1255	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	9	34	theme	cardiovascular	1115:1128	arg1	diseases					1130:1137	cardiovascular diseases	1115:1137	cardiovascular diseases	1115:1137	These results lead us to the conclusion that this functional coating is great potential in treating cardiovascular diseases in terms of promoting endothelialization, reducing thrombus, and maintaining the long-term patency of vascular grafts.					
36057293	6	35	theme	mechanical	738:747	arg1	properties					749:758	the mechanical properties	734:758	the mechanical properties	734:758	The composite coating enhanced the surface hydrophilicity of PCL scaffold, as well as the mechanical properties.					
36057293	1	36	theme	Surface	140:146	arg1	modifications					148:160	Surface modifications	140:160	Surface modifications	140:160	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	1	36	theme	Surface	140:146	arg1	approaches					173:182	common approaches	166:182	common approaches	166:182	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	3	37	theme	present	401:407	arg1	study					409:413	the present study	397:413	the present study	397:413	In the present study, dopamine was firstly grafted to the HA molecules.					
36057293	0	38	with	modification	8:19	arg1	coating					57:63	hydrophilic and heparin-loaded coating	26:63	hydrophilic and heparin-loaded coating	26:63	Surface modification with hydrophilic and heparin-loaded coating for endothelialization and anticoagulation promotion of vascular scaffold.					
36057293	7	39	theme	heparin	906:912	arg1	addition					914:921	heparin addition	906:921	heparin addition	906:921	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36057293	8	40	theme	effective	944:952	arg1	inhibition					954:963	more effective inhibition	939:963	more effective inhibition of platelet adhesion and blood clotting	939:1003	It also showed more effective inhibition of platelet adhesion and blood clotting in vitro.					
36057293	1	41	theme	common	166:171	arg1	modifications					148:160	Surface modifications	140:160	Surface modifications	140:160	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	1	41	theme	common	166:171	arg1	approaches					173:182	common approaches	166:182	common approaches	166:182	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	1	42	theme	vascular	276:283	arg1	grafts					285:290	vascular grafts	276:290	vascular grafts	276:290	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	1	43	theme	grafts	285:290	arg1	patency					265:271	long-term patency	255:271	long-term patency of vascular grafts	255:290	Surface modifications are common approaches to promote endothelialization and resist thrombus, therefore obtaining long-term patency of vascular grafts.					
36057293	7	44	theme	gene	876:879	arg1	expression					881:890	CD31 gene expression	871:890	CD31 gene expression	871:890	Notably, the coated scaffold could promote EC proliferation and angiogenesis behavior via the upregulation of CD31 gene expression regardless of heparin addition.					
36174273	3	0	theme	physical	537:544	arg1	properties					564:573	mechanical, physical and biodegradable properties	525:573	mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method	525:620	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	1	1	theme	ultrasonic	181:190	arg1	treatment					192:200	ultrasonic treatment	181:200	ultrasonic treatment of styrene emulsion in cellulose-water solution	181:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	3	2	theme	biodegradable	550:562	arg1	properties					564:573	mechanical, physical and biodegradable properties	525:573	mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method	525:620	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	3	theme	composite	582:590	arg1	properties					564:573	mechanical, physical and biodegradable properties	525:573	mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method	525:620	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	4	theme	mechanical	525:534	arg1	properties					564:573	mechanical, physical and biodegradable properties	525:573	mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method	525:620	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	5	theme	significant	493:503	arg1	differences					505:515	any significant differences	489:515	any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h)	489:760	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	6	theme	comprehensive	451:463	arg1	analysis					465:472	A comprehensive analysis	449:472	A comprehensive analysis	449:472	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	2	7	theme	additional	298:307	arg1	heating					309:315	additional heating	298:315	additional heating	298:315	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	0	8	theme	rapid	2:6	arg1	synthesis					8:16	A rapid synthesis	0:16	A rapid synthesis of nanofibrillar	0:33	A rapid synthesis of nanofibrillar cellulose/polystyrene composite via ultrasonic treatment.					
36174273	1	9	theme	new	95:97	arg1	method					99:104	A new method	93:104	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution	93:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	1	10	theme	styrene	205:211	arg1	emulsion					213:220	styrene emulsion	205:220	styrene emulsion in cellulose-water solution	205:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	2	11	theme	faster	346:351	arg1	synthesis					353:361	a significantly faster synthesis	330:361	a significantly faster synthesis (15 min, 45 °C) of the target composite	330:401	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	2	12	theme	composite	393:401	arg1	synthesis					353:361	a significantly faster synthesis	330:361	a significantly faster synthesis (15 min, 45 °C) of the target composite	330:401	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	3	13	from	3 h	757:759	arg1	duration					742:749	reaction duration	733:749	reaction duration (from 3 h)	733:760	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	13	from	3 h	757:759	arg1	temperature					703:713	much higher temperature	691:713	much higher temperature (above 75 °C)	691:727	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	13	from	3 h	757:759	arg1	75 °C					722:726	above 75 °C	716:726	above 75 °C	716:726	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	14	theme	ultrasonic	604:613	arg1	method					615:620	ultrasonic method	604:620	ultrasonic method	604:620	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	1	15	theme	cellulose-water	225:239	arg1	solution					241:248	cellulose-water solution	225:248	cellulose-water solution	225:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	3	16	theme	higher	696:701	arg1	temperature					703:713	much higher temperature	691:713	much higher temperature (above 75 °C)	691:727	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	16	theme	higher	696:701	arg1	75 °C					722:726	above 75 °C	716:726	above 75 °C	716:726	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	2	17	theme	new	268:270	arg1	approach					272:279	A new approach	266:279	A new approach	266:279	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	1	18	theme	emulsion	213:220	arg1	treatment					192:200	ultrasonic treatment	181:200	ultrasonic treatment of styrene emulsion in cellulose-water solution	181:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	0	19	theme	nanofibrillar	21:33	arg1	synthesis					8:16	A rapid synthesis	0:16	A rapid synthesis of nanofibrillar	0:33	A rapid synthesis of nanofibrillar cellulose/polystyrene composite via ultrasonic treatment.					
36174273	1	20	from	solution	241:248	arg1	treatment					192:200	ultrasonic treatment	181:200	ultrasonic treatment of styrene emulsion in cellulose-water solution	181:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	1	21	theme	synthesis	113:121	arg1	method					99:104	A new method	93:104	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution	93:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	3	22	theme	above	716:720	arg1	temperature					703:713	much higher temperature	691:713	much higher temperature (above 75 °C)	691:727	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	22	theme	above	716:720	arg1	75 °C					722:726	above 75 °C	716:726	above 75 °C	716:726	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	1	23	theme	composite	162:170	arg1	synthesis					113:121	the synthesis	109:121	the synthesis of nanofibrillar cellulose/polystyrene composite	109:170	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	1	24	theme	nanofibrillar	126:138	arg1	composite					162:170	nanofibrillar cellulose/polystyrene composite	126:170	nanofibrillar cellulose/polystyrene composite	126:170	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	1	25	theme	cellulose/polystyrene	140:160	arg1	composite					162:170	nanofibrillar cellulose/polystyrene composite	126:170	nanofibrillar cellulose/polystyrene composite	126:170	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	2	26	dep	synthesis	353:361	arg1	45 °C					372:376	45 °C	372:376	45 °C	372:376	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	2	26	dep	synthesis	353:361	arg1	15 min					364:369	15 min	364:369	15 min	364:369	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	3	27	theme	conventional	647:658	arg1	method					668:673	conventional thermal method	647:673	conventional thermal method	647:673	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	1	28	from	emulsion	213:220	arg1	solution					241:248	cellulose-water solution	225:248	cellulose-water solution	225:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
36174273	2	29	theme	target	386:391	arg1	composite					393:401	the target composite	382:401	the target composite	382:401	A new approach does not require additional heating and proposes a significantly faster synthesis (15 min, 45 °C) of the target composite compared to the methods described previously.					
36174273	0	30	theme	ultrasonic	71:80	arg1	treatment					82:90	ultrasonic treatment	71:90	ultrasonic treatment	71:90	A rapid synthesis of nanofibrillar cellulose/polystyrene composite via ultrasonic treatment.					
36174273	3	31	theme	reaction	733:740	arg1	duration					742:749	reaction duration	733:749	reaction duration (from 3 h)	733:760	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	3	32	theme	thermal	660:666	arg1	method					668:673	conventional thermal method	647:673	conventional thermal method	647:673	A comprehensive analysis did not reveal any significant differences between mechanical, physical and biodegradable properties of the composite obtained by ultrasonic method and that one obtained by conventional thermal method, which requires much higher temperature (above 75 °C) and reaction duration (from 3 h).					
36174273	1	33	from	treatment	192:200	arg1	solution					241:248	cellulose-water solution	225:248	cellulose-water solution	225:248	A new method of the synthesis of nanofibrillar cellulose/polystyrene composite based on ultrasonic treatment of styrene emulsion in cellulose-water solution was elaborated.					
35609462	5	0	theme	crosslinked	802:812	arg1	starches					814:821	crosslinked starches	802:821	crosslinked starches	802:821	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	0	1	theme	gels	193:196	arg1	microstructure					151:164	microstructure	151:164	microstructure	151:164	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	1	theme	gels	193:196	arg1	texture					139:145	texture	139:145	texture	139:145	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	2	link	crosslinked	88:98	arg1	starch					100:105	crosslinked starch	88:105	crosslinked starch	88:105	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	3	dep	texture	356:362	arg1	the					352:354	the	352:354	the	352:354	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	2	4	theme	granules	515:522	arg1	surface					504:510	the surface	500:510	the surface of granules	500:522	The results showed clusters were formed by the agglomeration of starch, with oil on the surface of granules.					
35609462	1	5	theme	surimi/starch	386:398	arg1	gels					410:413	surimi/starch composite gels	386:413	surimi/starch composite gels	386:413	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	6	theme	composite	183:191	arg1	gels					193:196	surimi/starch composite gels	169:196	surimi/starch composite gels	169:196	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	6	7	theme	starch	1170:1175	arg1	viscosity					1157:1165	final and setback viscosity	1139:1165	final and setback viscosity of starch and the swollen size of starch granules in surimi gel	1139:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	4	8	theme	adverse	729:735	arg1	effect					737:742	an adverse effect	726:742	an adverse effect for a high crosslinking level	726:772	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	1	9	theme	different	280:288	arg1	starches					315:322	different oil-modified crosslinked starches	280:322	different oil-modified crosslinked starches	280:322	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	10	theme	starch	100:105	arg1	properties					74:83	gelatinization properties	59:83	gelatinization properties	59:83	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	10	theme	starch	100:105	arg1	relationship					117:128	their relationship	111:128	their relationship with the texture and microstructure of surimi/starch composite gels	111:196	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	10	theme	starch	100:105	arg1	structure					45:53	multiscale structure	34:53	multiscale structure	34:53	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	11	from	Effect	0:5	arg1	properties					74:83	gelatinization properties	59:83	gelatinization properties	59:83	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	11	from	Effect	0:5	arg1	relationship					117:128	their relationship	111:128	their relationship with the texture and microstructure of surimi/starch composite gels	111:196	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	11	from	Effect	0:5	arg1	structure					45:53	multiscale structure	34:53	multiscale structure	34:53	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	12	link	crosslinked	303:313	arg1	starches					315:322	different oil-modified crosslinked starches	280:322	different oil-modified crosslinked starches	280:322	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	4	13	dep	effect	737:742	arg1	contrast					714:721	contrast	714:721	contrast	714:721	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	6	14	theme	starch	1201:1206	arg1	granules					1208:1215	starch granules	1201:1215	starch granules in surimi gel	1201:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	1	15	theme	oil-modified	290:301	arg1	starches					315:322	different oil-modified crosslinked starches	280:322	different oil-modified crosslinked starches	280:322	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	16	theme	crosslinked	88:98	arg1	starch					100:105	crosslinked starch	88:105	crosslinked starch	88:105	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	17	theme	gels	410:413	arg1	microstructure					368:381	microstructure	368:381	microstructure	368:381	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	17	theme	gels	410:413	arg1	texture					356:362	texture	356:362	texture	356:362	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	18	theme	crosslinked	303:313	arg1	starches					315:322	different oil-modified crosslinked starches	280:322	different oil-modified crosslinked starches	280:322	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	3	19	theme	long-range	561:570	arg1	structure					584:592	the long-range crystalline structure	557:592	the long-range crystalline structure	557:592	Oil modification did not damage the long-range crystalline structure but impaired the short-range ordered structure.					
35609462	6	20	from	gel	1227:1229	arg1	starch					1170:1175	starch	1170:1175	starch	1170:1175	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	20	from	gel	1227:1229	arg1	size					1193:1196	the swollen size	1181:1196	the swollen size of starch granules in surimi gel	1181:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	21	theme	setback	1149:1155	arg1	viscosity					1157:1165	final and setback viscosity	1139:1165	final and setback viscosity of starch and the swollen size of starch granules in surimi gel	1139:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	5	22	theme	lower	836:840	arg1	temperature					850:860	lower pasting temperature	836:860	lower pasting temperature	836:860	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	6	23	theme	swollen	1185:1191	arg1	size					1193:1196	the swollen size	1181:1196	the swollen size of starch granules in surimi gel	1181:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	3	24	theme	crystalline	572:582	arg1	structure					584:592	the long-range crystalline structure	557:592	the long-range crystalline structure	557:592	Oil modification did not damage the long-range crystalline structure but impaired the short-range ordered structure.					
35609462	1	25	theme	composite	400:408	arg1	gels					410:413	surimi/starch composite gels	386:413	surimi/starch composite gels	386:413	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	5	26	theme	pasting	842:848	arg1	temperature					850:860	lower pasting temperature	836:860	lower pasting temperature	836:860	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	6	27	theme	surimi	1220:1225	arg1	gel					1227:1229	surimi gel	1220:1229	surimi gel	1220:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	1	28	with	relationship	334:345	arg1	microstructure					368:381	microstructure	368:381	microstructure	368:381	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	28	with	relationship	334:345	arg1	texture					356:362	texture	356:362	texture	356:362	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	3	29	theme	short-range	611:621	arg1	structure					631:639	the short-range ordered structure	607:639	the short-range ordered structure	607:639	Oil modification did not damage the long-range crystalline structure but impaired the short-range ordered structure.					
35609462	6	30	dep	structure	1063:1071	arg1	the					1051:1053	the	1051:1053	the	1051:1053	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	31	theme	final	1139:1143	arg1	viscosity					1157:1165	final and setback viscosity	1139:1165	final and setback viscosity of starch and the swollen size of starch granules in surimi gel	1139:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	2	32	from	oil	493:495	arg1	surface					504:510	the surface	500:510	the surface of granules	500:522	The results showed clusters were formed by the agglomeration of starch, with oil on the surface of granules.					
35609462	1	33	theme	starches	315:322	arg1	structure					237:245	multiscale structure	226:245	multiscale structure	226:245	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	33	theme	starches	315:322	arg1	properties					266:275	gelatinization properties	251:275	gelatinization properties	251:275	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	33	theme	starches	315:322	arg1	relationship					334:345	their relationship	328:345	their relationship with the texture and microstructure of surimi/starch composite gels	328:413	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	3	34	theme	ordered	623:629	arg1	structure					631:639	the short-range ordered structure	607:639	the short-range ordered structure	607:639	Oil modification did not damage the long-range crystalline structure but impaired the short-range ordered structure.					
35609462	6	35	from	granules	1208:1215	arg1	gel					1227:1229	surimi gel	1220:1229	surimi gel	1220:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	5	36	theme	better	915:920	arg1	effect					938:943	better gel-reinforcing effect	915:943	better gel-reinforcing effect	915:943	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	0	37	theme	modification	14:25	arg1	Effect					0:5	Effect	0:5	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.	0:197	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	6	38	theme	granules	1208:1215	arg1	starch					1170:1175	starch	1170:1175	starch	1170:1175	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	38	theme	granules	1208:1215	arg1	size					1193:1196	the swollen size	1181:1196	the swollen size of starch granules in surimi gel	1181:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	0	39	theme	oil	10:12	arg1	modification					14:25	oil modification	10:25	oil modification	10:25	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	5	40	link	crosslinked	802:812	arg1	starches					814:821	crosslinked starches	802:821	crosslinked starches	802:821	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	5	41	theme	gel-reinforcing	922:936	arg1	effect					938:943	better gel-reinforcing effect	915:943	better gel-reinforcing effect	915:943	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	6	42	from	starch	1170:1175	arg1	gel					1227:1229	surimi gel	1220:1229	surimi gel	1220:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	0	43	dep	structure	45:53	arg1	the					30:32	the	30:32	the	30:32	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	4	44	theme	starch	693:698	arg1	structure					700:708	starch structure	693:708	starch structure	693:708	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	6	45	theme	Correlation	946:956	arg1	analysis					958:965	Correlation analysis	946:965	Correlation analysis	946:965	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	1	46	dep	structure	237:245	arg1	the					222:224	the	222:224	the	222:224	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	47	theme	multiscale	226:235	arg1	structure					237:245	multiscale structure	226:245	multiscale structure	226:245	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	6	48	theme	gels	1015:1018	arg1	texture					980:986	the texture	976:986	the texture of surimi/starch composite gels	976:1018	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	5	49	theme	gelatinization	866:879	arg1	enthalpy					881:888	gelatinization enthalpy	866:888	gelatinization enthalpy	866:888	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	3	50	theme	Oil	525:527	arg1	modification					529:540	Oil modification	525:540	Oil modification	525:540	Oil modification did not damage the long-range crystalline structure but impaired the short-range ordered structure.					
35609462	0	51	theme	multiscale	34:43	arg1	structure					45:53	multiscale structure	34:53	multiscale structure	34:53	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	6	52	theme	surimi/starch	991:1003	arg1	gels					1015:1018	surimi/starch composite gels	991:1018	surimi/starch composite gels	991:1018	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	53	theme	helical	1055:1061	arg1	structure					1063:1071	helical structure	1055:1071	helical structure	1055:1071	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	54	theme	size	1193:1196	arg1	viscosity					1157:1165	final and setback viscosity	1139:1165	final and setback viscosity of starch and the swollen size of starch granules in surimi gel	1139:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	0	55	theme	surimi/starch	169:181	arg1	gels					193:196	surimi/starch composite gels	169:196	surimi/starch composite gels	169:196	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	5	56	contain	had	832:834	arg2	enthalpy					881:888	gelatinization enthalpy	866:888	gelatinization enthalpy	866:888	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	5	56	contain	had	832:834	arg2	temperature					850:860	lower pasting temperature	836:860	lower pasting temperature	836:860	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	5	56	contain	had	832:834	arg1	Oil-CTS					824:830	Oil-CTS	824:830	Oil-CTS	824:830	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	5	56	contain	had	832:834	arg2	effect					938:943	better gel-reinforcing effect	915:943	better gel-reinforcing effect	915:943	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	5	56	contain	had	832:834	arg2	viscosity					900:908	a higher viscosity	891:908	a higher viscosity	891:908	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	0	57	with	properties	74:83	arg1	microstructure					151:164	microstructure	151:164	microstructure	151:164	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	57	with	properties	74:83	arg1	texture					139:145	texture	139:145	texture	139:145	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	4	58	theme	crosslinking	755:766	arg1	level					768:772	a high crosslinking level	748:772	a high crosslinking level	748:772	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	4	59	theme	modification	653:664	arg1	degree					666:671	A high oil modification degree	642:671	A high oil modification degree	642:671	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	6	60	from	size	1193:1196	arg1	gel					1227:1229	surimi gel	1220:1229	surimi gel	1220:1229	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	2	61	dep	showed	428:433	arg1	formed					449:454	formed	449:454	formed	449:454	The results showed clusters were formed by the agglomeration of starch, with oil on the surface of granules.					
35609462	0	62	with	structure	45:53	arg1	microstructure					151:164	microstructure	151:164	microstructure	151:164	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	62	with	structure	45:53	arg1	texture					139:145	texture	139:145	texture	139:145	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	4	63	theme	high	750:753	arg1	level					768:772	a high crosslinking level	748:772	a high crosslinking level	748:772	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	4	64	theme	oil	649:651	arg1	degree					666:671	A high oil modification degree	642:671	A high oil modification degree	642:671	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	0	65	theme	gelatinization	59:72	arg1	properties					74:83	gelatinization properties	59:83	gelatinization properties	59:83	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	5	66	theme	higher	893:898	arg1	viscosity					900:908	a higher viscosity	891:908	a higher viscosity	891:908	Furthermore, compared with crosslinked starches, Oil-CTS had lower pasting temperature and gelatinization enthalpy, a higher viscosity, and better gel-reinforcing effect.					
35609462	1	67	with	properties	266:275	arg1	microstructure					368:381	microstructure	368:381	microstructure	368:381	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	67	with	properties	266:275	arg1	texture					356:362	texture	356:362	texture	356:362	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	68	dep	texture	139:145	arg1	the					135:137	the	135:137	the	135:137	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	69	with	relationship	117:128	arg1	microstructure					151:164	microstructure	151:164	microstructure	151:164	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	0	69	with	relationship	117:128	arg1	texture					139:145	texture	139:145	texture	139:145	Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	70	theme	gelatinization	251:264	arg1	properties					266:275	gelatinization properties	251:275	gelatinization properties	251:275	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	4	71	theme	high	644:647	arg1	degree					666:671	A high oil modification degree	642:671	A high oil modification degree	642:671	A high oil modification degree was shown to weaken starch structure, in contrast to an adverse effect for a high crosslinking level.					
35609462	2	72	theme	starch	480:485	arg1	agglomeration					463:475	the agglomeration	459:475	the agglomeration of starch	459:485	The results showed clusters were formed by the agglomeration of starch, with oil on the surface of granules.					
35609462	1	73	with	structure	237:245	arg1	microstructure					368:381	microstructure	368:381	microstructure	368:381	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	1	73	with	structure	237:245	arg1	texture					356:362	texture	356:362	texture	356:362	This work investigated the multiscale structure and gelatinization properties of different oil-modified crosslinked starches and their relationship with the texture and microstructure of surimi/starch composite gels.					
35609462	6	74	theme	starch	1100:1105	arg1	structure					1063:1071	helical structure	1055:1071	helical structure	1055:1071	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	74	theme	starch	1100:1105	arg1	temperature					1085:1095	pasting temperature	1077:1095	pasting temperature	1077:1095	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	75	theme	composite	1005:1013	arg1	gels					1015:1018	surimi/starch composite gels	991:1018	surimi/starch composite gels	991:1018	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
35609462	6	76	theme	pasting	1077:1083	arg1	temperature					1085:1095	pasting temperature	1077:1095	pasting temperature	1077:1095	Correlation analysis revealed the texture of surimi/starch composite gels was negatively correlated with the helical structure and pasting temperature of starch, and positively correlated with final and setback viscosity of starch and the swollen size of starch granules in surimi gel.					
36069316	10	0	theme	expected	1127:1134	arg1	behaviors					1177:1185	The expected iodine loading, release and preservation behaviors	1123:1185	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites	1123:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	10	1	theme	release	1152:1158	arg1	behaviors					1177:1185	The expected iodine loading, release and preservation behaviors	1123:1185	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites	1123:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	0	2	theme	antibacterial	93:105	arg1	performance					107:117	their antibacterial performance	87:117	their antibacterial performance	87:117	Zeolitic imidazolate framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance.					
36069316	10	3	theme	clinical	1278:1285	arg1	applications					1287:1298	potential clinical applications	1268:1298	potential clinical applications	1268:1298	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	9	4	theme	Raman	1019:1023	arg1	analyses					1025:1032	XPS and Raman analyses	1011:1032	XPS and Raman analyses	1011:1032	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	9	5	theme	adsorbed	1053:1060	arg1	iodine					1062:1067	the adsorbed iodine	1049:1067	the adsorbed iodine of BC/ZIF-8-iodine composites	1049:1097	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	10	6	theme	potential	1268:1276	arg1	applications					1287:1298	potential clinical applications	1268:1298	potential clinical applications	1268:1298	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	8	7	theme	Candida	993:999	arg1	albicans					1001:1008	Candida albicans	993:1008	Candida albicans	993:1008	BC/ZIF-8-iodine composites exhibited strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans.					
36069316	5	8	theme	loading	588:594	arg1	capacity					596:603	the loading capacity	584:603	the loading capacity of iodine in BC/ZIF-8-iodine	584:632	The increase of ZIF-8 content augmented the loading capacity of iodine in BC/ZIF-8-iodine.					
36069316	9	9	theme	I3-	1118:1120	arg1	form					1110:1113	the form	1106:1113	the form of I3-	1106:1120	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	10	10	theme	loading	1143:1149	arg1	behaviors					1177:1185	The expected iodine loading, release and preservation behaviors	1123:1185	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites	1123:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	9	11	theme	composites	1088:1097	arg1	iodine					1062:1067	the adsorbed iodine	1049:1067	the adsorbed iodine of BC/ZIF-8-iodine composites	1049:1097	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	6	12	theme	BC/ZIF-8-iodine	687:701	arg1	composites					703:712	BC/ZIF-8-iodine composites	687:712	BC/ZIF-8-iodine composites	687:712	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	3	13	theme	loading	362:368	arg1	iodine					370:375	loading iodine	362:375	loading iodine	362:375	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	10	14	theme	iodine	1136:1141	arg1	loading					1143:1149	iodine loading	1136:1149	iodine loading	1136:1149	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	5	15	theme	iodine	608:613	arg1	capacity					596:603	the loading capacity	584:603	the loading capacity of iodine in BC/ZIF-8-iodine	584:632	The increase of ZIF-8 content augmented the loading capacity of iodine in BC/ZIF-8-iodine.					
36069316	2	16	theme	broad	274:278	arg1	applications					280:291	its broad applications	270:291	its broad applications	270:291	However, non-antibacterial activity limits its broad applications.					
36069316	7	17	theme	iodine	845:850	arg1	ability					865:871	their good iodine preservation ability	834:871	their good iodine preservation ability	834:871	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	10	18	theme	BC/ZIF-8-iodine	1190:1204	arg1	composites					1206:1215	BC/ZIF-8-iodine composites	1190:1215	BC/ZIF-8-iodine composites	1190:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	3	19	theme	framework-8	403:413	arg1	BC/ZIF-8					436:443	BC/ZIF-8	436:443	BC/ZIF-8	436:443	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	19	theme	framework-8	403:413	arg1	BC					432:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC	382:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8)	382:444	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	8	20	theme	strong	911:916	arg1	activity					932:939	strong antibacterial activity	911:939	strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans	911:1008	BC/ZIF-8-iodine composites exhibited strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans.					
36069316	6	21	attach	released	673:680	arg2	Meanwhile					635:643	Meanwhile	635:643	Meanwhile	635:643	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	6	21	attach	released	673:680	arg2	iodine					659:664	the adsorbed iodine	646:664	the adsorbed iodine	646:664	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	6	21	attach	released	673:680	arg1	composites					703:712	BC/ZIF-8-iodine composites	687:712	BC/ZIF-8-iodine composites	687:712	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	7	22	theme	preservation	852:863	arg1	ability					865:871	their good iodine preservation ability	834:871	their good iodine preservation ability	834:871	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	7	23	theme	BC/ZIF-8-iodine	795:809	arg1	composites					811:820	BC/ZIF-8-iodine composites	795:820	BC/ZIF-8-iodine composites	795:820	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	5	24	theme	ZIF-8	560:564	arg1	content					566:572	ZIF-8 content	560:572	ZIF-8 content	560:572	The increase of ZIF-8 content augmented the loading capacity of iodine in BC/ZIF-8-iodine.					
36069316	1	25	theme	Bacterial	120:128	arg1	BC					141:142	BC	141:142	BC	141:142	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	1	25	theme	Bacterial	120:128	arg1	cellulose					130:138	Bacterial cellulose	120:138	Bacterial cellulose (BC)	120:143	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	1	25	theme	Bacterial	120:128	arg1	material					193:200	a promising material	181:200	a promising material in the biomedical field	181:224	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	1	26	theme	promising	183:191	arg1	cellulose					130:138	Bacterial cellulose	120:138	Bacterial cellulose (BC)	120:143	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	1	26	theme	promising	183:191	arg1	material					193:200	a promising material	181:200	a promising material in the biomedical field	181:224	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	3	27	theme	zeolitic	382:389	arg1	BC/ZIF-8					436:443	BC/ZIF-8	436:443	BC/ZIF-8	436:443	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	27	theme	zeolitic	382:389	arg1	BC					432:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC	382:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8)	382:444	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	4	28	theme	angle	528:532	arg1	analyses					534:541	contact angle analyses	520:541	contact angle analyses	520:541	BC/ZIF-8-iodine was well characterized by SEM, XRD, FTIR, XPS, Raman and contact angle analyses.					
36069316	5	29	theme	content	566:572	arg1	increase					548:555	The increase	544:555	The increase of ZIF-8 content	544:572	The increase of ZIF-8 content augmented the loading capacity of iodine in BC/ZIF-8-iodine.					
36069316	7	30	theme	good	840:843	arg1	ability					865:871	their good iodine preservation ability	834:871	their good iodine preservation ability	834:871	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	3	31	theme	imidazolate	391:401	arg1	BC/ZIF-8					436:443	BC/ZIF-8	436:443	BC/ZIF-8	436:443	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	31	theme	imidazolate	391:401	arg1	BC					432:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC	382:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8)	382:444	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	7	32	located	observed	783:790	arg2	sublimation					757:767	A reduced sublimation	747:767	A reduced sublimation of iodine	747:777	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	7	32	located	observed	783:790	arg1	composites					811:820	BC/ZIF-8-iodine composites	795:820	BC/ZIF-8-iodine composites	795:820	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	3	33	theme	modified	423:430	arg1	BC/ZIF-8					436:443	BC/ZIF-8	436:443	BC/ZIF-8	436:443	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	33	theme	modified	423:430	arg1	BC					432:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC	382:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8)	382:444	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	8	34	theme	BC/ZIF-8-iodine	874:888	arg1	composites					890:899	BC/ZIF-8-iodine composites	874:899	BC/ZIF-8-iodine composites	874:899	BC/ZIF-8-iodine composites exhibited strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans.					
36069316	6	35	theme	adsorbed	650:657	arg1	Meanwhile					635:643	Meanwhile	635:643	Meanwhile	635:643	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	6	35	theme	adsorbed	650:657	arg1	iodine					659:664	the adsorbed iodine	646:664	the adsorbed iodine	646:664	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	0	36	theme	framework-8/bacterial	21:41	arg1	composites					53:62	framework-8/bacterial cellulose composites	21:62	framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance	21:117	Zeolitic imidazolate framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance.					
36069316	7	37	theme	iodine	772:777	arg1	sublimation					757:767	A reduced sublimation	747:767	A reduced sublimation of iodine	747:777	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	0	38	theme	cellulose	43:51	arg1	composites					53:62	framework-8/bacterial cellulose composites	21:62	framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance	21:117	Zeolitic imidazolate framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance.					
36069316	1	39	theme	biomedical	209:218	arg1	field					220:224	the biomedical field	205:224	the biomedical field	205:224	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	3	40	theme	ZIF-8	416:420	arg1	BC/ZIF-8					436:443	BC/ZIF-8	436:443	BC/ZIF-8	436:443	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	40	theme	ZIF-8	416:420	arg1	BC					432:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC	382:433	zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8)	382:444	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	10	41	theme	composites	1206:1215	arg1	behaviors					1177:1185	The expected iodine loading, release and preservation behaviors	1123:1185	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites	1123:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	10	42	theme	preservation	1164:1175	arg1	behaviors					1177:1185	The expected iodine loading, release and preservation behaviors	1123:1185	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites	1123:1215	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	0	43	theme	iodine	68:73	arg1	loading					75:81	iodine loading	68:81	iodine loading	68:81	Zeolitic imidazolate framework-8/bacterial cellulose composites for iodine loading and their antibacterial performance.					
36069316	4	44	theme	contact	520:526	arg1	analyses					534:541	contact angle analyses	520:541	contact angle analyses	520:541	BC/ZIF-8-iodine was well characterized by SEM, XRD, FTIR, XPS, Raman and contact angle analyses.					
36069316	1	45	from	material	193:200	arg1	field					220:224	the biomedical field	205:224	the biomedical field	205:224	Bacterial cellulose (BC), produced by bacteria and fungi, is a promising material in the biomedical field.					
36069316	3	46	theme	antibacterial	302:314	arg1	BC/ZIF-8-iodine					328:342	BC/ZIF-8-iodine	328:342	BC/ZIF-8-iodine	328:342	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	3	46	theme	antibacterial	302:314	arg1	composites					316:325	antibacterial composites	302:325	antibacterial composites (BC/ZIF-8-iodine)	302:343	Herein, antibacterial composites (BC/ZIF-8-iodine) were prepared by loading iodine into zeolitic imidazolate framework-8 (ZIF-8) modified BC (BC/ZIF-8).					
36069316	6	47	theme	Higuchi	729:735	arg1	equation					737:744	the Higuchi equation	725:744	the Higuchi equation	725:744	Meanwhile, the adsorbed iodine can be released from BC/ZIF-8-iodine composites, following the Higuchi equation.					
36069316	8	48	theme	antibacterial	918:930	arg1	activity					932:939	strong antibacterial activity	911:939	strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans	911:1008	BC/ZIF-8-iodine composites exhibited strong antibacterial activity towards Escherichia coli, Staphylococcus aureus and Candida albicans.					
36069316	9	49	theme	BC/ZIF-8-iodine	1072:1086	arg1	composites					1088:1097	BC/ZIF-8-iodine composites	1072:1097	BC/ZIF-8-iodine composites	1072:1097	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	7	50	theme	reduced	749:755	arg1	sublimation					757:767	A reduced sublimation	747:767	A reduced sublimation of iodine	747:777	A reduced sublimation of iodine was observed in BC/ZIF-8-iodine composites, indicating their good iodine preservation ability.					
36069316	9	51	theme	XPS	1011:1013	arg1	analyses					1025:1032	XPS and Raman analyses	1011:1032	XPS and Raman analyses	1011:1032	XPS and Raman analyses indicated that the adsorbed iodine of BC/ZIF-8-iodine composites was in the form of I3-.					
36069316	10	52	theme	antibacterial	1230:1242	arg1	performance					1244:1254	their antibacterial performance	1224:1254	their antibacterial performance	1224:1254	The expected iodine loading, release and preservation behaviors of BC/ZIF-8-iodine composites ensure their antibacterial performance and suggest potential clinical applications.					
36069316	2	53	theme	non-antibacterial	236:252	arg1	activity					254:261	non-antibacterial activity	236:261	non-antibacterial activity	236:261	However, non-antibacterial activity limits its broad applications.					
36069316	5	54	from	capacity	596:603	arg1	BC/ZIF-8-iodine					618:632	BC/ZIF-8-iodine	618:632	BC/ZIF-8-iodine	618:632	The increase of ZIF-8 content augmented the loading capacity of iodine in BC/ZIF-8-iodine.					
36113602	3	0	theme	gel	650:652	arg1	SP					641:642	the SP	637:642	the SP of YS gel by 3.24 g/g and 6.03 g/g	637:677	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	4	1	theme	pasting	805:811	arg1	process					813:819	the pasting process	801:819	the pasting process	801:819	In the pasting process, HMT reduced pasting viscosity of the HMT/YS system because only little amylose was leached in the medium for elevating its viscosity after HMT.					
36113602	1	2	theme	production	248:257	arg1	demand					228:233	demand	228:233	demand of practical production owing to the poor gel properties	228:290	Nowadays，It is difficult for the polysaccharide-starch system to meet demand of practical production owing to the poor gel properties.					
36113602	2	3	theme	YS/CS	517:521	arg1	gels					534:537	yam starch/chitosan (YS/CS) composite gels	496:537	yam starch/chitosan (YS/CS) composite gels	496:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	3	4	theme	swollen	782:788	arg1	starch					790:795	the swollen starch	778:795	the swollen starch	778:795	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	2	5	theme	yam	496:498	arg1	gels					534:537	yam starch/chitosan (YS/CS) composite gels	496:537	yam starch/chitosan (YS/CS) composite gels	496:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	7	6	theme	YS/CS	1374:1378	arg1	system					1384:1389	YS/CS gel system	1374:1389	YS/CS gel system	1374:1389	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	5	7	theme	granules	1098:1105	arg1	disintegration					1073:1086	disintegration	1073:1086	disintegration	1073:1086	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	5	7	theme	granules	1098:1105	arg1	disruption					1058:1067	disruption	1058:1067	disruption	1058:1067	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	3	8	theme	phase	737:741	arg1	rheology					715:722	the rheology	711:722	the rheology of the water phase inhibiting the entry of water into the swollen starch	711:795	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	0	9	theme	microstructure	74:87	arg1	properties					89:98	pasting, rheological, and microstructure properties	48:98	properties	89:98	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	7	10	theme	gel	1356:1358	arg1	properties					1360:1369	the gel properties	1352:1369	the gel properties of YS/CS gel system	1352:1389	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	7	11	theme	gel	1380:1382	arg1	system					1384:1389	YS/CS gel system	1374:1389	YS/CS gel system	1374:1389	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	5	12	theme	decline	1139:1145	arg1	trend					1147:1151	a decline trend	1137:1151	a decline trend	1137:1151	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	0	13	theme	Chinese	103:109	arg1	gels					131:134	Chinese yam starch-chitosan gels	103:134	Chinese yam starch-chitosan gels	103:134	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	5	14	theme	high	1008:1011	arg1	treatment					1025:1033	high temperature treatment	1008:1033	high temperature treatment of HMT	1008:1040	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	6	15	theme	gels	1186:1189	arg1	properties					1166:1175	The elastic properties	1154:1175	The elastic properties of GA/YS gels	1154:1189	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	5	16	dep	disruption	1058:1067	arg1	the					1054:1056	the	1054:1056	the	1054:1056	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	4	17	theme	HMT/YS	859:864	arg1	system					866:871	the HMT/YS system	855:871	the HMT/YS system	855:871	In the pasting process, HMT reduced pasting viscosity of the HMT/YS system because only little amylose was leached in the medium for elevating its viscosity after HMT.					
36113602	5	18	theme	temperature	1013:1023	arg1	treatment					1025:1033	high temperature treatment	1008:1033	high temperature treatment of HMT	1008:1040	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	6	19	theme	GA/YS	1180:1184	arg1	gels					1186:1189	GA/YS gels	1180:1189	GA/YS gels	1180:1189	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	0	20	theme	Gallic	0:5	arg1	acid					7:10	Gallic acid	0:10	Gallic acid	0:10	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	4	21	theme	system	866:871	arg1	viscosity					842:850	pasting viscosity	834:850	pasting viscosity of the HMT/YS system	834:871	In the pasting process, HMT reduced pasting viscosity of the HMT/YS system because only little amylose was leached in the medium for elevating its viscosity after HMT.					
36113602	2	22	theme	moisture	427:434	arg1	HMT					447:449	HMT	447:449	HMT	447:449	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	22	theme	moisture	427:434	arg1	treatment					436:444	heat moisture treatment	422:444	heat moisture treatment (HMT)	422:450	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	4	23	theme	little	886:891	arg1	amylose					893:899	only little amylose	881:899	only little amylose	881:899	In the pasting process, HMT reduced pasting viscosity of the HMT/YS system because only little amylose was leached in the medium for elevating its viscosity after HMT.					
36113602	5	24	theme	starch	1091:1096	arg1	granules					1098:1105	starch granules	1091:1105	starch granules	1091:1105	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	2	25	theme	heat	422:425	arg1	HMT					447:449	HMT	447:449	HMT	447:449	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	25	theme	heat	422:425	arg1	treatment					436:444	heat moisture treatment	422:444	heat moisture treatment (HMT)	422:450	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	1	26	theme	poor	272:275	arg1	properties					281:290	the poor gel properties	268:290	the poor gel properties	268:290	Nowadays，It is difficult for the polysaccharide-starch system to meet demand of practical production owing to the poor gel properties.					
36113602	6	27	located	observed	1279:1286	arg2	lamellar					1270:1277	the thicken lamellar	1258:1277	the thicken lamellar observed in its microstructure	1258:1308	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	6	27	located	observed	1279:1286	arg1	microstructure					1295:1308	its microstructure	1291:1308	its microstructure	1291:1308	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	5	28	theme	rheological	970:980	arg1	properties					982:991	The rheological properties	966:991	The rheological properties	966:991	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	0	29	theme	heat	16:19	arg1	treatment					30:38	heat moisture treatment	16:38	heat moisture treatment	16:38	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	1	30	theme	gel	277:279	arg1	properties					281:290	the poor gel properties	268:290	the poor gel properties	268:290	Nowadays，It is difficult for the polysaccharide-starch system to meet demand of practical production owing to the poor gel properties.					
36113602	0	31	theme	starch-chitosan	115:129	arg1	gels					131:134	Chinese yam starch-chitosan gels	103:134	Chinese yam starch-chitosan gels	103:134	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	6	32	theme	elastic	1158:1164	arg1	properties					1166:1175	The elastic properties	1154:1175	The elastic properties of GA/YS gels	1154:1189	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	5	33	theme	HMT	1038:1040	arg1	treatment					1025:1033	high temperature treatment	1008:1033	high temperature treatment of HMT	1008:1040	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	0	34	theme	yam	111:113	arg1	gels					131:134	Chinese yam starch-chitosan gels	103:134	Chinese yam starch-chitosan gels	103:134	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	4	35	theme	pasting	834:840	arg1	viscosity					842:850	pasting viscosity	834:850	pasting viscosity of the HMT/YS system	834:871	In the pasting process, HMT reduced pasting viscosity of the HMT/YS system because only little amylose was leached in the medium for elevating its viscosity after HMT.					
36113602	1	36	theme	polysaccharide-starch	191:211	arg1	system					213:218	the polysaccharide-starch system	187:218	the polysaccharide-starch system	187:218	Nowadays，It is difficult for the polysaccharide-starch system to meet demand of practical production owing to the poor gel properties.					
36113602	5	37	theme	dynamic	1117:1123	arg1	modulus					1125:1131	dynamic modulus	1117:1131	dynamic modulus had a decline trend	1117:1151	The rheological properties suggested that high temperature treatment of HMT facilitated the disruption and disintegration of starch granules resulting dynamic modulus had a decline trend.					
36113602	3	38	theme	HMT	602:604	arg1	treatment					606:614	GA and HMT treatment	595:614	treatment	606:614	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	3	39	theme	power	564:568	arg1	results					575:581	Swell power (SP) results	558:581	Swell power (SP) results	558:581	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	7	40	theme	system	1384:1389	arg1	properties					1360:1369	the gel properties	1352:1369	the gel properties of YS/CS gel system	1352:1389	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	2	41	theme	acid	408:411	arg1	effects					390:396	the effects	386:396	the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels	386:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	0	42	theme	moisture	21:28	arg1	treatment					30:38	heat moisture treatment	16:38	heat moisture treatment	16:38	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	0	43	theme	gels	131:134	arg1	rheological					57:67	rheological	57:67	rheological	57:67	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	7	44	theme	practical	1411:1419	arg1	application					1421:1431	its practical application	1407:1431	its practical application in food industry	1407:1448	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	2	45	theme	starch/chitosan	500:514	arg1	gels					534:537	yam starch/chitosan (YS/CS) composite gels	496:537	yam starch/chitosan (YS/CS) composite gels	496:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	46	theme	gallic	401:406	arg1	acid					408:411	gallic acid	401:411	gallic acid (GA)	401:416	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	46	theme	gallic	401:406	arg1	GA					414:415	GA	414:415	GA	414:415	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	7	47	from	application	1421:1431	arg1	industry					1441:1448	food industry	1436:1448	food industry	1436:1448	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	0	48	theme	comparative	139:149	arg1	study					151:155	A comparative study	137:155	A comparative study	137:155	Gallic acid and heat moisture treatment improve pasting, rheological, and microstructure properties of Chinese yam starch-chitosan gels: A comparative study.					
36113602	3	49	theme	GA	595:596	arg1	treatment					606:614	GA and HMT treatment	595:614	treatment	606:614	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	2	50	dep	properties	463:472	arg1	the					455:457	the	455:457	the	455:457	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	51	theme	practical	334:342	arg1	application					344:354	the practical application	330:354	the practical application of polysaccharide-starch gel	330:383	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	52	theme	treatment	436:444	arg1	effects					390:396	the effects	386:396	the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels	386:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	6	53	theme	GA	1226:1227	arg1	addition					1214:1221	the addition	1210:1221	the addition	1210:1221	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	3	54	theme	Swell	558:562	arg1	results					575:581	Swell power (SP) results	558:581	Swell power (SP) results	558:581	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	7	55	theme	food	1436:1439	arg1	industry					1441:1448	food industry	1436:1448	food industry	1436:1448	In general, GA and HMT effectively alter the gel properties of YS/CS gel system, and facilitate its practical application in food industry.					
36113602	2	56	theme	gels	534:537	arg1	microstructure					478:491	microstructure	478:491	microstructure	478:491	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	56	theme	gels	534:537	arg1	properties					463:472	gel properties	459:472	gel properties	459:472	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	57	from	effects	390:396	arg1	microstructure					478:491	microstructure	478:491	microstructure	478:491	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	57	from	effects	390:396	arg1	properties					463:472	gel properties	459:472	gel properties	459:472	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	2	58	theme	composite	524:532	arg1	gels					534:537	yam starch/chitosan (YS/CS) composite gels	496:537	yam starch/chitosan (YS/CS) composite gels	496:537	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	6	59	theme	thicken	1262:1268	arg1	lamellar					1270:1277	the thicken lamellar	1258:1277	the thicken lamellar observed in its microstructure	1258:1308	The elastic properties of GA/YS gels were enhanced with the addition of GA, which could be supported by the thicken lamellar observed in its microstructure.					
36113602	3	60	theme	water	731:735	arg1	phase					737:741	the water phase	727:741	the water phase inhibiting the entry of water into the swollen starch	727:795	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	3	61	theme	SP	571:572	arg1	results					575:581	Swell power (SP) results	558:581	Swell power (SP) results	558:581	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	2	62	theme	gel	381:383	arg1	application					344:354	the practical application	330:354	the practical application of polysaccharide-starch gel	330:383	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	3	63	theme	water	767:771	arg1	entry					758:762	the entry	754:762	the entry of water into the swollen starch	754:795	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	2	64	theme	gel	459:461	arg1	properties					463:472	gel properties	459:472	gel properties	459:472	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	3	65	theme	YS	647:648	arg1	gel					650:652	YS gel	647:652	YS gel	647:652	Swell power (SP) results showed that GA and HMT treatment respectively reduced the SP of YS gel by 3.24 g/g and 6.03 g/g, given that GA and HMT decrease the rheology of the water phase inhibiting the entry of water into the swollen starch.					
36113602	2	66	theme	polysaccharide-starch	359:379	arg1	gel					381:383	polysaccharide-starch gel	359:383	polysaccharide-starch gel	359:383	Therefore, aiming to further improve the practical application of polysaccharide-starch gel, the effects of gallic acid (GA) and heat moisture treatment (HMT) on the gel properties and microstructure of yam starch/chitosan (YS/CS) composite gels were investigated.					
36113602	1	67	theme	practical	238:246	arg1	production					248:257	practical production	238:257	practical production owing to the poor gel properties	238:290	Nowadays，It is difficult for the polysaccharide-starch system to meet demand of practical production owing to the poor gel properties.					
36500427	2	0	theme	biological	343:352	arg1	tissue					354:359	biological tissue	343:359	biological tissue	343:359	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	5	1	theme	alginate	911:918	arg1	M/G~0.61					929:936	M/G~0.61	929:936	M/G~0.61	929:936	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	1	theme	alginate	911:918	arg1	samples					920:926	guluronic-rich alginate samples	896:926	guluronic-rich alginate samples (M/G~0.61)	896:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	2	theme	%	847:847	arg1	reduction					849:857	a 20% reduction	843:857	a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61)	843:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	0	3	from	Role	0:3	arg1	Uptake					43:48	Copper Ion Uptake	32:48	Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid	32:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	5	4	from	reduction	849:857	arg1	capacity					884:891	the copper adsorption capacity	862:891	the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61)	862:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	4	5	theme	adsorption	683:692	arg1	capacities					694:703	similar Cu(II) adsorption capacities	668:703	similar Cu(II) adsorption capacities	668:703	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	0	6	theme	Histidine	69:77	arg1	Presence					57:64	the Presence	53:64	the Presence of Histidine or Beta-Amyloid	53:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	0	7	from	Uptake	43:48	arg1	Presence					57:64	the Presence	53:64	the Presence of Histidine or Beta-Amyloid	53:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	6	8	theme	guluronic-rich	1221:1234	arg1	alginate					1236:1243	guluronic-rich alginate	1221:1243	guluronic-rich alginate	1221:1243	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	3	9	from	adsorption	473:482	arg1	role					430:433	the role	426:433	the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease	426:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	3	10	theme	histidine	503:511	arg1	presence					491:498	the presence	487:498	the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease	487:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	2	11	with	aspects	302:308	arg1	tissue					354:359	biological tissue	343:359	biological tissue	343:359	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	4	12	theme	similar	668:674	arg1	capacities					694:703	similar Cu(II) adsorption capacities	668:703	similar Cu(II) adsorption capacities	668:703	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	4	13	theme	Langmuir	720:727	arg1	isotherm					729:736	the Langmuir isotherm	716:736	the Langmuir isotherm	716:736	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	5	14	theme	copper	866:871	arg1	capacity					884:891	the copper adsorption capacity	862:891	the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61)	862:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	1	15	theme	peptide	149:155	arg1	beta-amyloid					157:168	the peptide beta-amyloid	145:168	the peptide beta-amyloid	145:168	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	0	16	theme	Beta-Amyloid	82:93	arg1	Presence					57:64	the Presence	53:64	the Presence of Histidine or Beta-Amyloid	53:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	6	17	theme	interaction	1204:1214	arg1	prevalence					1180:1189	the prevalence	1176:1189	the prevalence of histidine interaction with guluronic-rich alginate	1176:1243	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	3	18	from	composition	451:461	arg1	adsorption					473:482	Cu(II) adsorption	466:482	Cu(II) adsorption	466:482	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	6	19	theme	ion	1100:1102	arg1	chelation					1104:1112	copper ion chelation	1093:1112	copper ion chelation	1093:1112	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	20	dep	analyses	1012:1019	arg1	XPS					1031:1033	XPS	1031:1033	XPS	1031:1033	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	20	dep	analyses	1012:1019	arg1	FTIR					1022:1025	FTIR	1022:1025	FTIR	1022:1025	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	20	dep	analyses	1012:1019	arg1	analyses					1012:1019	Chemical analyses	1003:1019	Chemical analyses (FTIR and XPS)	1003:1034	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	21	dep	demonstrated	1036:1047	arg1	whereas					1115:1121	whereas	1115:1121	whereas	1115:1121	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	22	theme	histidine	1194:1202	arg1	interaction					1204:1214	histidine interaction	1194:1214	histidine interaction with guluronic-rich alginate	1194:1243	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	23	theme	copper	1093:1098	arg1	chelation					1104:1112	copper ion chelation	1093:1112	copper ion chelation	1093:1112	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	7	24	theme	simple	1414:1419	arg1	system					1402:1407	the alginate/histidine system	1379:1407	the alginate/histidine system	1379:1407	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	24	theme	simple	1414:1419	arg1	model					1440:1444	a simple yet representative model	1412:1444	a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors	1412:1546	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	25	theme	Cu	1280:1281	arg1	adsorption					1287:1296	Cu(II) adsorption	1280:1296	Cu(II) adsorption	1280:1296	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	4	26	theme	Cu	676:677	arg1	capacities					694:703	similar Cu(II) adsorption capacities	668:703	similar Cu(II) adsorption capacities	668:703	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	5	27	theme	histidine	818:826	arg1	presence					806:813	the presence	802:813	the presence of histidine	802:826	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	28	theme	metallic	989:996	arg1	ion					998:1000	the metallic ion	985:1000	the metallic ion	985:1000	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	7	29	theme	alginate/histidine	1383:1400	arg1	system					1402:1407	the alginate/histidine system	1379:1407	the alginate/histidine system	1379:1407	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	29	theme	alginate/histidine	1383:1400	arg1	model					1440:1444	a simple yet representative model	1412:1444	a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors	1412:1546	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	4	30	theme	mannuronic/guluronic	627:646	arg1	ratios					654:659	different mannuronic/guluronic (M/G) ratios	617:659	different mannuronic/guluronic (M/G) ratios	617:659	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	0	31	theme	Composition	17:27	arg1	Role					0:3	Role	0:3	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.	0:94	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	5	32	theme	adsorption	873:882	arg1	capacity					884:891	the copper adsorption capacity	862:891	the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61)	862:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	2	33	theme	fundamental	290:300	arg1	aspects					302:308	the fundamental aspects	286:308	the fundamental aspects of metal ions	286:322	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	5	34	theme	bidentate	962:970	arg1	chelation					972:980	stable bidentate chelation	955:980	stable bidentate chelation of the metallic ion	955:1000	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	6	35	theme	Chemical	1003:1010	arg1	XPS					1031:1033	XPS	1031:1033	XPS	1031:1033	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	35	theme	Chemical	1003:1010	arg1	FTIR					1022:1025	FTIR	1022:1025	FTIR	1022:1025	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	6	35	theme	Chemical	1003:1010	arg1	analyses					1012:1019	Chemical analyses	1003:1019	Chemical analyses (FTIR and XPS)	1003:1034	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	0	36	theme	Alginate	8:15	arg1	Composition					17:27	Alginate Composition	8:27	Alginate Composition	8:27	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	7	37	theme	histidine	1352:1360	arg1	presence					1323:1330	the presence	1319:1330	the presence of beta-amyloid and histidine	1319:1360	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	38	theme	metal	1489:1493	arg1	uptake					1499:1504	metal ion uptake	1489:1504	metal ion uptake	1489:1504	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	3	39	theme	β-amyloid	516:524	arg1	presence					491:498	the presence	487:498	the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease	487:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	3	40	theme	disease	586:592	arg1	progression					559:569	the progression	555:569	the progression of Alzheimer's disease	555:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	3	41	theme	alginate	442:449	arg1	composition					451:461	the alginate composition	438:461	the alginate composition on Cu(II) adsorption	438:482	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	0	42	theme	Copper	32:37	arg1	Uptake					43:48	Copper Ion Uptake	32:48	Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid	32:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	6	43	theme	hydroxyl	1061:1068	arg1	groups					1083:1088	hydroxyl and carboxyl groups	1061:1088	groups	1083:1088	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	7	44	located	observed	1267:1274	arg2	results					1254:1260	Similar results	1246:1260	Similar results	1246:1260	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	44	located	observed	1267:1274	arg1	beads					1310:1314	alginate beads	1301:1314	alginate beads in the presence of beta-amyloid and histidine	1301:1360	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	4	45	theme	kinetic	777:783	arg1	models					785:790	kinetic models	777:790	kinetic models	777:790	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	4	46	dep	isotherm	729:736	arg1	models					785:790	kinetic models	777:790	kinetic models	777:790	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	1	47	theme	hallmarks	184:192	arg1	interaction					110:120	The anomalous interaction	96:120	The anomalous interaction between metal ions and the peptide beta-amyloid	96:168	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	1	47	theme	hallmarks	184:192	arg1	one					173:175	one	173:175	one	173:175	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	1	47	theme	hallmarks	184:192	arg1	hallmarks					184:192	the hallmarks	180:192	the hallmarks of Alzheimer's disease	180:215	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	4	48	theme	different	617:625	arg1	ratios					654:659	different mannuronic/guluronic (M/G) ratios	617:659	different mannuronic/guluronic (M/G) ratios	617:659	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	7	49	theme	beta-amyloid	1335:1346	arg1	presence					1323:1330	the presence	1319:1330	the presence of beta-amyloid and histidine	1319:1360	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	2	50	with	interactions	325:336	arg1	tissue					354:359	biological tissue	343:359	biological tissue	343:359	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	3	51	from	role	430:433	arg1	adsorption					473:482	Cu(II) adsorption	466:482	Cu(II) adsorption	466:482	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	3	51	from	role	430:433	arg1	presence					491:498	the presence	487:498	the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease	487:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	4	52	theme	Alginate	595:602	arg1	samples					604:610	Alginate samples	595:610	Alginate samples with different mannuronic/guluronic (M/G) ratios	595:659	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	6	53	dep	crystallinity	1128:1140	arg1	analyses					1157:1164	analyses	1157:1164	analyses	1157:1164	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	7	54	from	beads	1310:1314	arg1	presence					1323:1330	the presence	1319:1330	the presence of beta-amyloid and histidine	1319:1360	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	6	55	from	role	1053:1056	arg1	chelation					1104:1112	copper ion chelation	1093:1112	copper ion chelation	1093:1112	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	3	56	theme	Cu	466:467	arg1	adsorption					473:482	Cu(II) adsorption	466:482	Cu(II) adsorption	466:482	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	0	57	theme	Ion	39:41	arg1	Uptake					43:48	Copper Ion Uptake	32:48	Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid	32:93	Role of Alginate Composition on Copper Ion Uptake in the Presence of Histidine or Beta-Amyloid.					
36500427	4	58	with	samples	604:610	arg1	ratios					654:659	different mannuronic/guluronic (M/G) ratios	617:659	different mannuronic/guluronic (M/G) ratios	617:659	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	6	59	theme	groups	1083:1088	arg1	role					1053:1056	the role	1049:1056	the role of hydroxyl and carboxyl groups in copper ion chelation	1049:1112	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	1	60	theme	anomalous	100:108	arg1	interaction					110:120	The anomalous interaction	96:120	The anomalous interaction between metal ions and the peptide beta-amyloid	96:168	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	1	60	theme	anomalous	100:108	arg1	one					173:175	one	173:175	one	173:175	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	1	60	theme	anomalous	100:108	arg1	hallmarks					184:192	the hallmarks	180:192	the hallmarks of Alzheimer's disease	180:215	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	7	61	theme	ion	1495:1497	arg1	uptake					1499:1504	metal ion uptake	1489:1504	metal ion uptake	1489:1504	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	5	62	theme	stable	955:960	arg1	chelation					972:980	stable bidentate chelation	955:980	stable bidentate chelation of the metallic ion	955:1000	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	63	theme	ion	998:1000	arg1	chelation					972:980	stable bidentate chelation	955:980	stable bidentate chelation of the metallic ion	955:1000	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	7	64	theme	alginate	1301:1308	arg1	beads					1310:1314	alginate beads	1301:1314	alginate beads in the presence of beta-amyloid and histidine	1301:1360	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	2	65	theme	ions	319:322	arg1	interactions					325:336	interactions	325:336	interactions with biological tissue	325:359	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	2	65	theme	ions	319:322	arg1	aspects					302:308	the fundamental aspects	286:308	the fundamental aspects of metal ions	286:322	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	2	65	theme	ions	319:322	arg1	interplay					371:379	their interplay	365:379	their interplay in Alzheimer's disease	365:402	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	5	66	theme	guluronic-rich	896:909	arg1	M/G~0.61					929:936	M/G~0.61	929:936	M/G~0.61	929:936	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	66	theme	guluronic-rich	896:909	arg1	samples					920:926	guluronic-rich alginate samples	896:926	guluronic-rich alginate samples (M/G~0.61)	896:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	6	67	theme	carboxyl	1074:1081	arg1	groups					1083:1088	hydroxyl and carboxyl groups	1061:1088	groups	1083:1088	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	7	68	theme	Similar	1246:1252	arg1	results					1254:1260	Similar results	1246:1260	Similar results	1246:1260	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	2	69	theme	metal	313:317	arg1	ions					319:322	metal ions	313:322	metal ions	313:322	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	5	70	from	capacity	884:891	arg1	M/G~0.61					929:936	M/G~0.61	929:936	M/G~0.61	929:936	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	5	70	from	capacity	884:891	arg1	samples					920:926	guluronic-rich alginate samples	896:926	guluronic-rich alginate samples (M/G~0.61)	896:937	Although the presence of histidine produced up to a 20% reduction in the copper adsorption capacity in guluronic-rich alginate samples (M/G~0.61), they presented stable bidentate chelation of the metallic ion.					
36500427	3	71	theme	composition	451:461	arg1	role					430:433	the role	426:433	the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease	426:592	This work focuses on the role of the alginate composition on Cu(II) adsorption in the presence of histidine or β-amyloid, the peptide associated with the progression of Alzheimer's disease.					
36500427	6	72	with	interaction	1204:1214	arg1	alginate					1236:1243	guluronic-rich alginate	1221:1243	guluronic-rich alginate	1221:1243	Chemical analyses (FTIR and XPS) demonstrated the role of hydroxyl and carboxyl groups in copper ion chelation, whereas both crystallinity and morphology analyses indicated the prevalence of histidine interaction with guluronic-rich alginate.					
36500427	4	73	theme	pseudo-second-order	746:764	arg1	adsorption					766:775	the pseudo-second-order adsorption	742:775	the pseudo-second-order adsorption	742:775	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	7	74	theme	competitors	1536:1546	arg1	presence					1513:1520	the presence	1509:1520	the presence of biological competitors	1509:1546	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	1	75	theme	metal	130:134	arg1	ions					136:139	metal ions	130:139	metal ions	130:139	The anomalous interaction between metal ions and the peptide beta-amyloid is one of the hallmarks of Alzheimer's disease.					
36500427	7	76	theme	representative	1425:1438	arg1	system					1402:1407	the alginate/histidine system	1379:1407	the alginate/histidine system	1379:1407	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	7	76	theme	representative	1425:1438	arg1	model					1440:1444	a simple yet representative model	1412:1444	a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors	1412:1546	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	2	77	with	interplay	371:379	arg1	tissue					354:359	biological tissue	343:359	biological tissue	343:359	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	2	78	theme	Metal-binding	218:230	arg1	biopolymers					232:242	Metal-binding biopolymers	218:242	Metal-binding biopolymers	218:242	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	2	78	theme	Metal-binding	218:230	arg1	polysaccharides					255:269	polysaccharides	255:269	polysaccharides	255:269	Metal-binding biopolymers, including polysaccharides, can elucidate the fundamental aspects of metal ions' interactions with biological tissue and their interplay in Alzheimer's disease.					
36500427	7	79	theme	biopolymers	1474:1484	arg1	application					1459:1469	the application	1455:1469	the application of biopolymers to metal ion uptake	1455:1504	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
36500427	4	80	theme	M/G	649:651	arg1	ratios					654:659	different mannuronic/guluronic (M/G) ratios	617:659	different mannuronic/guluronic (M/G) ratios	617:659	Alginate samples with different mannuronic/guluronic (M/G) ratios led to similar Cu(II) adsorption capacities, following the Langmuir isotherm and the pseudo-second-order adsorption kinetic models.					
36500427	7	81	theme	biological	1525:1534	arg1	competitors					1536:1546	biological competitors	1525:1546	biological competitors	1525:1546	Similar results were observed for Cu(II) adsorption in alginate beads in the presence of beta-amyloid and histidine, suggesting that the alginate/histidine system is a simple yet representative model to probe the application of biopolymers to metal ion uptake in the presence of biological competitors.					
35259437	8	0	theme	cancer	1160:1165	arg1	studies					1167:1173	Liver and lung cancer studies	1145:1173	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4	1145:1195	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	6	1	theme	cancer	980:985	arg1	lines					992:996	cancer cell lines	980:996	cancer cell lines	980:996	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	11	2	dep	demonstrates	1490:1501	arg1	nanocomposite					1520:1532	nanocomposite	1520:1532	nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells	1520:1625	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	7	3	theme	Antioxidant	999:1009	arg1	potential					1011:1019	Antioxidant potential	999:1019	Antioxidant potential of Ag/CS-Agar@Fe3O4	999:1039	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	1	4	theme	core-shell	268:277	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	4	theme	core-shell	268:277	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	5	5	theme	consecutive	790:800	arg1	times					805:809	consecutive 10 times	790:809	consecutive 10 times	790:809	Robustness of the catalyst was justified by catalyst recyclability for consecutive 10 times, hot filtration and leaching tests.					
35259437	10	6	theme	cell	1467:1470	arg1	line					1472:1475	normal cell line	1460:1475	normal cell line	1460:1475	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	6	7	dep	lung	965:968	arg1	lines					992:996	cancer cell lines	980:996	cancer cell lines	980:996	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	4	8	theme	solvent-less	694:705	arg1	conditions					707:716	solvent-less conditions	694:716	solvent-less conditions	694:716	It afforded good to excellent yields under solvent-less conditions.					
35259437	11	9	theme	@	1513:1513	arg1	Fe3O4					1514:1518	Ag/CS-Agar@Fe3O4	1503:1518	Ag/CS-Agar@Fe3O4	1503:1518	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	1	10	theme	type	279:282	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	10	theme	type	279:282	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	5	11	theme	catalyst	737:744	arg1	Robustness					719:728	Robustness	719:728	Robustness of the catalyst	719:744	Robustness of the catalyst was justified by catalyst recyclability for consecutive 10 times, hot filtration and leaching tests.					
35259437	11	12	theme	chemotherapeutic	1553:1568	arg1	drug					1570:1573	an efficient chemotherapeutic drug	1540:1573	an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells	1540:1625	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	3	13	theme	2H-indazolo0-b	511:524	arg1	derivatives					545:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	8	14	dep	HepG2	1234:1238	arg1	lines					1254:1258	cell lines	1249:1258	cell lines	1249:1258	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	1	15	theme	Fe3O4	284:288	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	15	theme	Fe3O4	284:288	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	0	16	theme	phthalazines	101:112	arg1	studies					129:135	indazolo[2,1-b]phthalazines and anticancer studies	86:135	indazolo[2,1-b]phthalazines and anticancer studies	86:135	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	10	17	dep	dependently	1395:1405	arg1	dose					1390:1393	dose	1390:1393	dose	1390:1393	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	6	18	dep	antioxidant	920:930	arg1	properties					949:958	properties	949:958	properties	949:958	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	0	19	theme	studies	129:135	arg1	synthesis					73:81	synthesis	73:81	synthesis of indazolo[2,1-b]phthalazines and anticancer studies	73:135	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	8	20	theme	cell	1249:1252	arg1	lines					1254:1258	cell lines	1249:1258	cell lines	1249:1258	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	4	21	theme	good	663:666	arg1	yields					681:686	good to excellent yields	663:686	good to excellent yields	663:686	It afforded good to excellent yields under solvent-less conditions.					
35259437	0	22	theme	anticancer	118:127	arg1	studies					129:135	indazolo[2,1-b]phthalazines and anticancer studies	86:135	indazolo[2,1-b]phthalazines and anticancer studies	86:135	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	6	23	theme	cell	987:990	arg1	lines					992:996	cancer cell lines	980:996	cancer cell lines	980:996	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	11	24	theme	carcinoma	1611:1619	arg1	cells					1621:1625	the lung and hepatocellular carcinoma cells	1583:1625	cells	1621:1625	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	0	25	dep	phthalazines	101:112	arg1	indazolo[2,1-b					86:99	indazolo[2,1-b	86:99	indazolo[2,1-b	86:99	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	8	26	theme	@	1190:1190	arg1	Fe3O4					1191:1195	Ag/CS-Agar@Fe3O4	1180:1195	Ag/CS-Agar@Fe3O4	1180:1195	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	8	27	theme	lung	1155:1158	arg1	studies					1167:1173	Liver and lung cancer studies	1145:1173	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4	1145:1195	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	7	28	theme	corresponding	1097:1109	arg1	96.57 μg/mL					1132:1142	96.57 μg/mL	1132:1142	96.57 μg/mL	1132:1142	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	7	28	theme	corresponding	1097:1109	arg1	IC50					1111:1114	the corresponding IC50	1093:1114	the corresponding IC50	1093:1114	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	10	29	theme	cell	1421:1424	arg1	lines					1426:1430	both the cell lines	1412:1430	both the cell lines	1412:1430	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	2	30	theme	biogenic	327:334	arg1	material					336:343	The biogenic material	323:343	The biogenic material	323:343	The biogenic material was analyzed over a number of physicochemical methods like, FT-IR, FE-SEM, TEM, EDX, XRD, VSM and ICP-OES.					
35259437	7	31	theme	radical	1062:1068	arg1	studies					1081:1087	DPPH radical scavenging studies	1057:1087	DPPH radical scavenging studies	1057:1087	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	4	32	theme	excellent	671:679	arg1	yields					681:686	good to excellent yields	663:686	good to excellent yields	663:686	It afforded good to excellent yields under solvent-less conditions.					
35259437	0	33	theme	Ag	0:1	arg1	NPs					3:5	Ag NPs	0:5	Ag NPs	0:5	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	8	34	theme	Ag/CS-Agar	1180:1189	arg1	Fe3O4					1191:1195	Ag/CS-Agar@Fe3O4	1180:1195	Ag/CS-Agar@Fe3O4	1180:1195	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	10	35	theme	normal	1460:1465	arg1	line					1472:1475	normal cell line	1460:1475	normal cell line	1460:1475	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	3	36	theme	one-pot	561:567	arg1	coupling					585:592	one-pot three component coupling	561:592	one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes	561:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	2	37	theme	methods	391:397	arg1	number					365:370	a number	363:370	a number of physicochemical methods like, FT-IR, FE-SEM, TEM, EDX, XRD, VSM and ICP-OES	363:449	The biogenic material was analyzed over a number of physicochemical methods like, FT-IR, FE-SEM, TEM, EDX, XRD, VSM and ICP-OES.					
35259437	5	38	theme	leaching	831:838	arg1	tests					840:844	leaching tests	831:844	leaching tests	831:844	Robustness of the catalyst was justified by catalyst recyclability for consecutive 10 times, hot filtration and leaching tests.					
35259437	1	39	theme	Ag/CS-Agar	304:313	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	39	theme	Ag/CS-Agar	304:313	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	0	40	theme	liver	145:149	arg1	cells					167:171	liver and lung cancer cells	145:171	liver and lung cancer cells	145:171	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	3	41	theme	phthalazine-trione	526:543	arg1	derivatives					545:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	11	42	theme	efficient	1543:1551	arg1	drug					1570:1573	an efficient chemotherapeutic drug	1540:1573	an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells	1540:1625	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	1	43	theme	@	314:314	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	43	theme	@	314:314	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	6	44	theme	material	881:888	arg1	activity					865:872	biological activity	854:872	biological activity of the material	854:888	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	3	45	theme	derivatives	545:555	arg1	synthesis					490:498	the synthesis	486:498	the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives	486:555	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	1	46	theme	novel	202:206	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	46	theme	novel	202:206	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	0	47	theme	Fe3O4	43:47	arg1	nanocomposite					49:61	modified Fe3O4 nanocomposite	34:61	modified Fe3O4 nanocomposite	34:61	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	10	48	from	cytotoxicity	1444:1455	arg1	line					1472:1475	normal cell line	1460:1475	normal cell line	1460:1475	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	0	49	theme	lung	155:158	arg1	cells					167:171	liver and lung cancer cells	145:171	liver and lung cancer cells	145:171	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	11	50	theme	hepatocellular	1596:1609	arg1	cells					1621:1625	the lung and hepatocellular carcinoma cells	1583:1625	cells	1621:1625	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	1	51	theme	Ag	208:209	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	51	theme	Ag	208:209	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	0	52	theme	modified	34:41	arg1	nanocomposite					49:61	modified Fe3O4 nanocomposite	34:61	modified Fe3O4 nanocomposite	34:61	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	4	53	dep	yields	681:686	arg1	to					668:669	to	668:669	to	668:669	It afforded good to excellent yields under solvent-less conditions.					
35259437	3	54	theme	different	630:638	arg1	aldehydes					640:648	different aldehydes	630:648	different aldehydes	630:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	7	55	theme	Fe3O4	1035:1039	arg1	potential					1011:1019	Antioxidant potential	999:1019	Antioxidant potential of Ag/CS-Agar@Fe3O4	999:1039	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	1	56	theme	NPs	211:213	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	56	theme	NPs	211:213	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	7	57	theme	DPPH	1057:1060	arg1	studies					1081:1087	DPPH radical scavenging studies	1057:1087	DPPH radical scavenging studies	1057:1087	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	3	58	theme	aldehydes	640:648	arg1	coupling					585:592	one-pot three component coupling	561:592	one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes	561:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	10	59	theme	%	1343:1343	arg1	viability					1350:1358	% Cell viability	1343:1358	% Cell viability of the nanomaterial	1343:1378	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	3	60	theme	catalytic	455:463	arg1	exploration					465:475	catalytic exploration	455:475	catalytic exploration	455:475	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	5	61	theme	hot	812:814	arg1	filtration					816:825	hot filtration	812:825	hot filtration	812:825	Robustness of the catalyst was justified by catalyst recyclability for consecutive 10 times, hot filtration and leaching tests.					
35259437	0	62	theme	cancer	160:165	arg1	cells					167:171	liver and lung cancer cells	145:171	liver and lung cancer cells	145:171	Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo[2,1-b]phthalazines and anticancer studies against liver and lung cancer cells.					
35259437	6	63	theme	biological	854:863	arg1	activity					865:872	biological activity	854:872	biological activity of the material	854:888	Again, biological activity of the material was evaluated by studying the antioxidant and cytotoxicity properties over lung and liver cancer cell lines.					
35259437	3	64	theme	component	575:583	arg1	coupling					585:592	one-pot three component coupling	561:592	one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes	561:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	7	65	theme	Ag/CS-Agar	1024:1033	arg1	Fe3O4					1035:1039	Ag/CS-Agar@Fe3O4	1024:1039	Ag/CS-Agar@Fe3O4	1024:1039	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	8	66	theme	MTT	1216:1218	arg1	assay					1220:1224	MTT assay	1216:1224	MTT assay	1216:1224	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	3	67	theme	dimedone	617:624	arg1	coupling					585:592	one-pot three component coupling	561:592	one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes	561:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	7	68	theme	@	1034:1034	arg1	Fe3O4					1035:1039	Ag/CS-Agar@Fe3O4	1024:1039	Ag/CS-Agar@Fe3O4	1024:1039	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	11	69	theme	Ag/CS-Agar	1503:1512	arg1	Fe3O4					1514:1518	Ag/CS-Agar@Fe3O4	1503:1518	Ag/CS-Agar@Fe3O4	1503:1518	The results demonstrates Ag/CS-Agar@Fe3O4 nanocomposite to be an efficient chemotherapeutic drug against the lung and hepatocellular carcinoma cells.					
35259437	1	70	theme	fabricated	215:224	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	70	theme	fabricated	215:224	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	3	71	theme	diverse	503:509	arg1	derivatives					545:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	diverse 2H-indazolo0-b]phthalazine-trione derivatives	503:555	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	10	72	theme	Cell	1345:1348	arg1	viability					1350:1358	% Cell viability	1343:1358	% Cell viability of the nanomaterial	1343:1378	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	10	73	theme	nanomaterial	1367:1378	arg1	viability					1350:1358	% Cell viability	1343:1358	% Cell viability of the nanomaterial	1343:1378	% Cell viability of the nanomaterial decreased dose dependently over both the cell lines without any cytotoxicity on normal cell line.					
35259437	1	74	theme	chitosan-agarose	226:241	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	74	theme	chitosan-agarose	226:241	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	5	75	theme	catalyst	763:770	arg1	recyclability					772:784	catalyst recyclability	763:784	catalyst recyclability	763:784	Robustness of the catalyst was justified by catalyst recyclability for consecutive 10 times, hot filtration and leaching tests.					
35259437	9	76	theme	corresponding	1265:1277	arg1	192.35					1305:1310	192.35	1305:1310	192.35	1305:1310	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	9	76	theme	corresponding	1265:1277	arg1	values					1284:1289	The corresponding IC50 values	1261:1289	The corresponding IC50 values	1261:1289	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	9	76	theme	corresponding	1265:1277	arg1	365.28 μg/mL					1316:1327	365.28 μg/mL	1316:1327	365.28 μg/mL	1316:1327	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	3	77	theme	phathalalhydrazide	597:614	arg1	coupling					585:592	one-pot three component coupling	561:592	one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes	561:648	In catalytic exploration we aimed the synthesis of diverse 2H-indazolo0-b]phthalazine-trione derivatives via one-pot three component coupling of phathalalhydrazide, dimedone and different aldehydes.					
35259437	2	78	theme	physicochemical	375:389	arg1	methods					391:397	physicochemical methods	375:397	physicochemical methods like, FT-IR, FE-SEM, TEM, EDX, XRD, VSM and ICP-OES	375:449	The biogenic material was analyzed over a number of physicochemical methods like, FT-IR, FE-SEM, TEM, EDX, XRD, VSM and ICP-OES.					
35259437	1	79	theme	composite	243:251	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	79	theme	composite	243:251	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	8	80	theme	Liver	1145:1149	arg1	studies					1167:1173	Liver and lung cancer studies	1145:1173	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4	1145:1195	Liver and lung cancer studies over Ag/CS-Agar@Fe3O4 was carried out by MTT assay against HepG2 and A549 cell lines.					
35259437	9	81	theme	IC50	1279:1282	arg1	192.35					1305:1310	192.35	1305:1310	192.35	1305:1310	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	9	81	theme	IC50	1279:1282	arg1	values					1284:1289	The corresponding IC50 values	1261:1289	The corresponding IC50 values	1261:1289	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	9	81	theme	IC50	1279:1282	arg1	365.28 μg/mL					1316:1327	365.28 μg/mL	1316:1327	365.28 μg/mL	1316:1327	The corresponding IC50 values were found as 192.35 and 365.28 μg/mL respectively.					
35259437	7	82	theme	scavenging	1070:1079	arg1	studies					1081:1087	DPPH radical scavenging studies	1057:1087	DPPH radical scavenging studies	1057:1087	Antioxidant potential of Ag/CS-Agar@Fe3O4 was assessed by DPPH radical scavenging studies and the corresponding IC50 was found to be 96.57 μg/mL.					
35259437	1	83	theme	functionalized	253:266	arg1	Fe3O4					315:319	Ag/CS-Agar@Fe3O4	304:319	Ag/CS-Agar@Fe3O4	304:319	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35259437	1	83	theme	functionalized	253:266	arg1	nanoparticle					290:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle	200:301	a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4)	200:320	In this article we report a novel Ag NPs fabricated chitosan-agarose composite functionalized core-shell type Fe3O4 nanoparticle (Ag/CS-Agar@Fe3O4).					
35427658	0	0	theme	algal	101:105	arg1	blooms					107:112	harmful algal blooms	93:112	harmful algal blooms	93:112	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	6	1	theme	suitable	1294:1301	arg1	sustainable					1262:1272	a promising sustainable	1250:1272	a promising sustainable	1250:1272	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	2	2	theme	compatible	342:351	arg1	media					377:381	environmentally compatible and economically viable media	326:381	environmentally compatible and economically viable media	326:381	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	1	3	theme	potent	224:229	arg1	cyanotoxins					181:191	cyanotoxins	181:191	cyanotoxins	181:191	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	1	3	theme	potent	224:229	arg1	microcystin					202:212	microcystin	202:212	microcystin (MC)	202:217	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	1	3	theme	potent	224:229	arg1	hazards					242:248	potent underlying hazards	224:248	potent underlying hazards produced by various species of cyanobacteria	224:293	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	0	4	theme	harmful	93:99	arg1	blooms					107:112	harmful algal blooms	93:112	harmful algal blooms	93:112	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	0	5	from	removal	18:24	arg1	chitosan/graphene					47:63	chitosan/graphene	47:63	chitosan/graphene	47:63	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	6	6	theme	selective	1278:1286	arg1	media					1288:1292	selective media	1278:1292	selective media	1278:1292	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	5	7	theme	chitosan	1032:1039	arg1	surface					1048:1054	the chitosan matrix surface	1028:1054	the chitosan matrix surface	1028:1054	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	1	8	theme	underlying	231:240	arg1	cyanotoxins					181:191	cyanotoxins	181:191	cyanotoxins	181:191	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	1	8	theme	underlying	231:240	arg1	microcystin					202:212	microcystin	202:212	microcystin (MC)	202:217	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	1	8	theme	underlying	231:240	arg1	hazards					242:248	potent underlying hazards	224:248	potent underlying hazards produced by various species of cyanobacteria	224:293	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	4	9	from	removal	831:837	arg1	effective					809:817	effective	809:817	effective	809:817	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	0	10	attach	removal	18:24	arg2	Microcystin-LR					29:42	Microcystin-LR	29:42	Microcystin-LR	29:42	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	0	10	attach	removal	18:24	arg3	chitosan/graphene					47:63	chitosan/graphene	47:63	chitosan/graphene	47:63	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	6	11	theme	removal	1168:1174	arg1	mechanism					1176:1184	This proposed π-π removal mechanism	1150:1184	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate	1150:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	0	12	theme	blooms	107:112	arg1	treatment					80:88	treatment	80:88	treatment of harmful algal blooms	80:112	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	4	13	contain	has	712:714	arg1	CSG					708:710	CSG	708:710	CSG	708:710	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	4	13	contain	has	712:714	arg2	removal					735:741	an algae dependent removal	716:741	an algae dependent removal of density	716:752	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	4	14	theme	density	746:752	arg1	removal					735:741	an algae dependent removal	716:741	an algae dependent removal of density	716:752	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	3	15	theme	CSG	503:505	arg1	composites					508:517	chitosan/graphene (CSG) composites	484:517	chitosan/graphene (CSG) composites	484:517	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	5	16	theme	π-π	1078:1080	arg1	interactions					1082:1093	π-π interactions	1078:1093	π-π interactions between graphene	1078:1110	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	3	17	with	interactions	468:479	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	17	with	interactions	468:479	arg1	sp					593:594	Synechocystis sp	579:594	Synechocystis sp	579:594	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	17	with	interactions	468:479	arg1	sp					575:576	Anabaena sp	566:576	Anabaena sp	566:576	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	4	18	theme	dependent	725:733	arg1	removal					735:741	an algae dependent removal	716:741	an algae dependent removal of density	716:752	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	6	19	theme	proposed	1155:1162	arg1	mechanism					1176:1184	This proposed π-π removal mechanism	1150:1184	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate	1150:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	6	20	theme	microcystin	1189:1199	arg1	mechanism					1176:1184	This proposed π-π removal mechanism	1150:1184	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate	1150:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	3	21	theme	different	530:538	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	21	theme	different	530:538	arg1	sp					593:594	Synechocystis sp	579:594	Synechocystis sp	579:594	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	21	theme	different	530:538	arg1	sp					575:576	Anabaena sp	566:576	Anabaena sp	566:576	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	4	22	theme	toxin	825:829	arg1	removal					831:837	MC toxin removal	822:837	MC toxin removal	822:837	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	3	23	theme	Anabaena	566:573	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	23	theme	Anabaena	566:573	arg1	sp					575:576	Anabaena sp	566:576	Anabaena sp	566:576	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	0	24	theme	Graphene-Mediated	0:16	arg1	removal					18:24	Graphene-Mediated removal	0:24	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene	0:63	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	5	25	theme	750 m2/g	945:952	arg1	graphene					967:974	750 m2/g surface area graphene	945:974	750 m2/g surface area graphene	945:974	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	4	26	theme	MC	822:823	arg1	removal					831:837	MC toxin removal	822:837	MC toxin removal	822:837	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	6	27	theme	chitosan	1213:1220	arg1	substrate					1233:1241	the CSG chitosan biopolymer substrate	1205:1241	the CSG chitosan biopolymer substrate	1205:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	6	28	theme	promising	1252:1260	arg1	sustainable					1262:1272	a promising sustainable	1250:1272	a promising sustainable	1250:1272	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	2	29	theme	viable	370:375	arg1	media					377:381	environmentally compatible and economically viable media	326:381	environmentally compatible and economically viable media	326:381	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	0	30	theme	Microcystin-LR	29:42	arg1	removal					18:24	Graphene-Mediated removal	0:24	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene	0:63	Graphene-Mediated removal of Microcystin-LR in chitosan/graphene composites for treatment of harmful algal blooms.					
35427658	1	31	theme	various	262:268	arg1	species					270:276	various species	262:276	various species of cyanobacteria	262:293	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	6	32	theme	waters	1344:1349	arg1	treatment					1318:1326	deployable treatment	1307:1326	deployable treatment of HAB impacted waters	1307:1349	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	1	33	theme	Water	115:119	arg1	quality					121:127	Water quality	115:127	Water quality	115:127	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	2	34	theme	HAB	422:424	arg1	waters					435:440	HAB impacted waters	422:440	HAB impacted waters	422:440	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	6	35	theme	impacted	1335:1342	arg1	waters					1344:1349	HAB impacted waters	1331:1349	HAB impacted waters	1331:1349	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	5	36	theme	matrix	1041:1046	arg1	surface					1048:1054	the chitosan matrix surface	1028:1054	the chitosan matrix surface	1028:1054	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	6	37	theme	HAB	1331:1333	arg1	waters					1344:1349	HAB impacted waters	1331:1349	HAB impacted waters	1331:1349	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	3	38	theme	algal	644:648	arg1	density					658:664	algal optical density	644:664	algal optical density	644:664	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	6	39	theme	biopolymer	1222:1231	arg1	substrate					1233:1241	the CSG chitosan biopolymer substrate	1205:1241	the CSG chitosan biopolymer substrate	1205:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	2	40	theme	scale	400:404	arg1	application					406:416	large scale application	394:416	large scale application for HAB impacted waters	394:440	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	1	41	theme	cyanobacteria	281:293	arg1	species					270:276	various species	262:276	various species of cyanobacteria	262:293	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35427658	6	42	theme	π-π	1164:1166	arg1	mechanism					1176:1184	This proposed π-π removal mechanism	1150:1184	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate	1150:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	2	43	theme	impacted	426:433	arg1	waters					435:440	HAB impacted waters	422:440	HAB impacted waters	422:440	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	2	44	theme	large	394:398	arg1	application					406:416	large scale application	394:416	large scale application for HAB impacted waters	394:440	Currently there is a need for environmentally compatible and economically viable media to address large scale application for HAB impacted waters.					
35427658	6	45	theme	CSG	1209:1211	arg1	substrate					1233:1241	the CSG chitosan biopolymer substrate	1205:1241	the CSG chitosan biopolymer substrate	1205:1241	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	3	46	theme	chitosan/graphene	484:500	arg1	composites					508:517	chitosan/graphene (CSG) composites	484:517	chitosan/graphene (CSG) composites	484:517	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	5	47	theme	aromatic	1120:1127	arg1	ring					1129:1132	the aromatic ring	1116:1132	the aromatic ring of microcystin	1116:1147	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	5	48	theme	microcystin	1137:1147	arg1	interactions					1082:1093	π-π interactions	1078:1093	π-π interactions between graphene	1078:1110	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	5	48	theme	microcystin	1137:1147	arg1	ring					1129:1132	the aromatic ring	1116:1132	the aromatic ring of microcystin	1116:1147	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	6	49	theme	deployable	1307:1316	arg1	treatment					1318:1326	deployable treatment	1307:1326	deployable treatment of HAB impacted waters	1307:1349	This proposed π-π removal mechanism of microcystin via the CSG chitosan biopolymer substrate offers a promising sustainable and selective media suitable for deployable treatment of HAB impacted waters.					
35427658	3	50	theme	Synechocystis	579:591	arg1	sp					593:594	Synechocystis sp	579:594	Synechocystis sp	579:594	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	50	theme	Synechocystis	579:591	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	5	51	theme	surface	954:960	arg1	graphene					967:974	750 m2/g surface area graphene	945:974	750 m2/g surface area graphene	945:974	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	4	52	theme	40-90	770:774	arg1	%					775:775	%	775:775	%	775:775	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	5	53	theme	graphene	985:992	arg1	morphology					994:1003	graphene morphology	985:1003	graphene morphology	985:1003	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	3	54	dep	species	540:546	arg1	sp					593:594	Synechocystis sp	579:594	Synechocystis sp	579:594	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	54	dep	species	540:546	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	54	dep	species	540:546	arg1	aeruginosa					613:622	Microcystis aeruginosa	601:622	Microcystis aeruginosa for both removal of algal optical density and toxins	601:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	54	dep	species	540:546	arg1	sp					575:576	Anabaena sp	566:576	Anabaena sp	566:576	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	55	theme	cyanobacteria	551:563	arg1	species					540:546	three different species	524:546	three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	524:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	55	theme	cyanobacteria	551:563	arg1	sp					593:594	Synechocystis sp	579:594	Synechocystis sp	579:594	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	55	theme	cyanobacteria	551:563	arg1	sp					575:576	Anabaena sp	566:576	Anabaena sp	566:576	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	4	56	theme	MC-LR	857:861	arg1	MC-LR					857:861	MC-LR	857:861	MC-LR produced by Microcystis aeruginosa	857:896	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	4	56	theme	MC-LR	857:861	arg1	%					852:852	>94%	849:852	>94% of MC-LR produced by Microcystis aeruginosa	849:896	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	3	57	theme	optical	650:656	arg1	density					658:664	algal optical density	644:664	algal optical density	644:664	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	5	58	theme	area	962:965	arg1	graphene					967:974	750 m2/g surface area graphene	945:974	750 m2/g surface area graphene	945:974	Characterization by SEM and XRD revealed that 750 m2/g surface area graphene, imparts graphene morphology and functionality into the chitosan matrix surface, potentially enabling π-π interactions between graphene and the aromatic ring of microcystin.					
35427658	3	59	theme	density	658:664	arg1	removal					633:639	removal	633:639	removal of algal optical density	633:664	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	3	59	theme	density	658:664	arg1	toxins					670:675	toxins	670:675	toxins	670:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	4	60	theme	removal	777:783	arg1	range					761:765	a range	759:765	a range of 40-90% removal	759:783	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	3	61	theme	composites	508:517	arg1	interactions					468:479	the interactions	464:479	the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins	464:675	This study evaluated the interactions of chitosan/graphene (CSG) composites with three different species of cyanobacteria: Anabaena sp, Synechocystis sp, and Microcystis aeruginosa for both removal of algal optical density and toxins.					
35427658	4	62	theme	%	775:775	arg1	removal					777:783	40-90% removal	770:783	40-90% removal	770:783	Although results suggest that CSG has an algae dependent removal of density with a range of 40-90% removal, graphene/CSG is highly effective at MC toxin removal, removing >94% of MC-LR produced by Microcystis aeruginosa.					
35427658	1	63	theme	algal	157:161	arg1	blooms					163:168	algal blooms	157:168	algal blooms alone	157:174	Water quality can be severely impacted by algal blooms alone, yet cyanotoxins, such as microcystin (MC), are potent underlying hazards produced by various species of cyanobacteria.					
35698371	4	0	theme	water	880:884	arg1	fractions					893:901	the different water volume fractions	866:901	the different water volume fractions contained therein	866:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	1	theme	dissolution	163:173	arg1	kinetics					175:182	the dissolution kinetics	159:182	the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels	159:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	0	2	theme	fibres	73:78	arg1	energy					52:57	the dissolution activation energy	25:57	the dissolution activation energy of cellulosic fibres	25:78	Three methods to measure the dissolution activation energy of cellulosic fibres using time-temperature superposition.					
35698371	1	3	theme	cellulose	347:355	arg1	hydrogels					357:365	processed dried cellulose and cellulose hydrogels	317:365	processed dried cellulose and cellulose hydrogels	317:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	4	theme	different	870:878	arg1	fractions					893:901	the different water volume fractions	866:901	the different water volume fractions contained therein	866:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	5	theme	hydrogels	357:365	arg1	images					307:312	optical microscopic images	287:312	optical microscopic images of processed dried cellulose and cellulose hydrogels	287:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	6	theme	fractions	893:901	arg1	regions					811:817	different regions	801:817	different regions of the processed cellulose samples, along with the different water volume fractions contained therein	801:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	7	from	kinetics	175:182	arg1	[C2mim					263:268	[C2mim	263:268	[C2mim	263:268	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	7	from	kinetics	175:182	arg1	acetate					254:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate	208:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc])	208:275	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	0	8	theme	time-temperature	86:101	arg1	superposition					103:115	time-temperature superposition	86:115	time-temperature superposition	86:115	Three methods to measure the dissolution activation energy of cellulosic fibres using time-temperature superposition.					
35698371	4	9	theme	volume	886:891	arg1	fractions					893:901	the different water volume fractions	866:901	the different water volume fractions contained therein	866:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	5	10	theme	cellulose	981:989	arg1	composites					991:1000	all cellulose composites	977:1000	all cellulose composites	977:1000	The findings will be of interest to researchers making all cellulose composites and those studying the dissolution of cellulose by ionic liquids.					
35698371	2	11	theme	different	396:404	arg1	times					406:410	different times	396:410	different times at various temperatures	396:434	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
35698371	3	12	theme	73 ± 2 kJ/mol	725:737	arg1	value					716:720	an average value	705:720	an average value of 73 ± 2 kJ/mol	705:737	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	4	13	theme	swelling	783:790	arg1	ratio					792:796	the swelling ratio	779:796	the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein	779:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	14	theme	cellulosic	187:196	arg1	fibres					198:203	cellulosic fibres	187:203	cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels	187:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	15	theme	fibres	198:203	arg1	kinetics					175:182	the dissolution kinetics	159:182	the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels	159:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	2	16	from	temperatures	423:434	arg1	times					406:410	different times	396:410	different times at various temperatures	396:434	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
35698371	2	17	theme	time-temperature	455:470	arg1	superposition					472:484	time-temperature superposition	455:484	time-temperature superposition	455:484	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
35698371	5	18	theme	ionic	1053:1057	arg1	liquids					1059:1065	ionic liquids	1053:1065	ionic liquids	1053:1065	The findings will be of interest to researchers making all cellulose composites and those studying the dissolution of cellulose by ionic liquids.					
35698371	4	19	theme	samples	846:852	arg1	regions					811:817	different regions	801:817	different regions of the processed cellulose samples, along with the different water volume fractions contained therein	801:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	4	20	theme	regions	811:817	arg1	ratio					792:796	the swelling ratio	779:796	the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein	779:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	21	theme	optical	287:293	arg1	images					307:312	optical microscopic images	287:312	optical microscopic images of processed dried cellulose and cellulose hydrogels	287:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	22	dep	[C2mim	263:268	arg1	[OAc					270:273	[OAc	270:273	[OAc	270:273	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	3	23	theme	activation	582:591	arg1	energy					593:598	the activation energy	578:598	the activation energy of dissolution	578:613	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	1	24	theme	ionic	212:216	arg1	[C2mim					263:268	[C2mim	263:268	[C2mim	263:268	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	24	theme	ionic	212:216	arg1	acetate					254:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate	208:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc])	208:275	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	0	25	theme	dissolution	29:39	arg1	energy					52:57	the dissolution activation energy	25:57	the dissolution activation energy of cellulosic fibres	25:78	Three methods to measure the dissolution activation energy of cellulosic fibres using time-temperature superposition.					
35698371	1	26	theme	microscopic	295:305	arg1	images					307:312	optical microscopic images	287:312	optical microscopic images of processed dried cellulose and cellulose hydrogels	287:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	27	theme	processed	826:834	arg1	samples					846:852	the processed cellulose samples	822:852	the processed cellulose samples	822:852	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	28	theme	liquid	218:223	arg1	[C2mim					263:268	[C2mim	263:268	[C2mim	263:268	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	28	theme	liquid	218:223	arg1	acetate					254:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate	208:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc])	208:275	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	29	dep	along	855:859	arg1	with					861:864	with	861:864	with	861:864	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	30	theme	1-ethyl-3-methyl-imidazolium	225:252	arg1	[C2mim					263:268	[C2mim	263:268	[C2mim	263:268	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	30	theme	1-ethyl-3-methyl-imidazolium	225:252	arg1	acetate					254:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate	208:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc])	208:275	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	3	31	theme	dissolution	603:613	arg1	energy					593:598	the activation energy	578:598	the activation energy of dissolution	578:613	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	0	32	theme	activation	41:50	arg1	energy					52:57	the dissolution activation energy	25:57	the dissolution activation energy of cellulosic fibres	25:78	Three methods to measure the dissolution activation energy of cellulosic fibres using time-temperature superposition.					
35698371	1	33	theme	processed	317:325	arg1	hydrogels					357:365	processed dried cellulose and cellulose hydrogels	317:365	processed dried cellulose and cellulose hydrogels	317:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	34	theme	cellulose	836:844	arg1	samples					846:852	the processed cellulose samples	822:852	the processed cellulose samples	822:852	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	35	theme	dried	327:331	arg1	hydrogels					357:365	processed dried cellulose and cellulose hydrogels	317:365	processed dried cellulose and cellulose hydrogels	317:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	36	from	acetate	254:260	arg1	kinetics					175:182	the dissolution kinetics	159:182	the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels	159:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	4	37	theme	different	801:809	arg1	regions					811:817	different regions	801:817	different regions of the processed cellulose samples, along with the different water volume fractions contained therein	801:919	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	3	38	theme	quantifying	650:660	arg1	methods					662:668	three different quantifying methods	634:668	three different quantifying methods	634:668	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	5	39	theme	cellulose	1040:1048	arg1	dissolution					1025:1035	the dissolution	1021:1035	the dissolution of cellulose by ionic liquids	1021:1065	The findings will be of interest to researchers making all cellulose composites and those studying the dissolution of cellulose by ionic liquids.					
35698371	4	40	theme	new	742:744	arg1	method					746:751	A new method	740:751	A new method	740:751	A new method is developed to determine the swelling ratio of different regions of the processed cellulose samples, along with the different water volume fractions contained therein.					
35698371	1	41	from	fibres	198:203	arg1	[C2mim					263:268	[C2mim	263:268	[C2mim	263:268	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	1	41	from	fibres	198:203	arg1	acetate					254:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate	208:260	the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc])	208:275	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	0	42	theme	cellulosic	62:71	arg1	fibres					73:78	cellulosic fibres	62:78	cellulosic fibres	62:78	Three methods to measure the dissolution activation energy of cellulosic fibres using time-temperature superposition.					
35698371	2	43	theme	various	415:421	arg1	temperatures					423:434	various temperatures	415:434	various temperatures	415:434	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
35698371	3	44	theme	average	708:714	arg1	value					716:720	an average value	705:720	an average value of 73 ± 2 kJ/mol	705:737	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	1	45	theme	cellulose	333:341	arg1	hydrogels					357:365	processed dried cellulose and cellulose hydrogels	317:365	processed dried cellulose and cellulose hydrogels	317:365	Three methods are established to explore the dissolution kinetics of cellulosic fibres in the ionic liquid 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]), based on optical microscopic images of processed dried cellulose and cellulose hydrogels.					
35698371	3	46	theme	different	640:648	arg1	methods					662:668	three different quantifying methods	634:668	three different quantifying methods	634:668	Three values for the activation energy of dissolution were obtained from three different quantifying methods; these were found to agree, giving an average value of 73 ± 2 kJ/mol.					
35698371	2	47	theme	dissolution	372:382	arg1	process					384:390	The dissolution process	368:390	The dissolution process for different times at various temperatures	368:434	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
35698371	2	48	theme	Arrhenius	540:548	arg1	behaviour					550:558	an Arrhenius behaviour	537:558	an Arrhenius behaviour	537:558	The dissolution process for different times at various temperatures was analysed using time-temperature superposition, and from this the dissolution was found to follow an Arrhenius behaviour.					
37230611	4	0	theme	starch	694:699	arg1	related					754:760	related	754:760	related	754:760	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	4	0	theme	starch	694:699	arg1	mobility					672:679	the mobility	668:679	the mobility of water and starch protons measured by time-domain NMR	668:735	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	1	1	theme	digestion	153:161	arg1	determinants					130:141	the determinants	126:141	the determinants of starch digestion from multiple interrelated properties	126:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	0	2	theme	starch	76:81	arg1	digestion					83:91	the wheat starch digestion	66:91	the wheat starch digestion	66:91	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	3	3	theme	techniques	538:547	arg1	range					520:524	a large range	512:524	a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…)	512:594	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	6	4	theme	other	999:1003	arg1	hand					1005:1008	the other hand	995:1008	the other hand	995:1008	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	2	5	with	starches	398:405	arg1	contents					430:437	different amylose contents	412:437	different amylose contents	412:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	2	6	theme	digestion	303:311	arg1	parameters					321:330	the digestion kinetic parameters	299:330	the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents	299:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	7	7	theme	chains	1185:1190	arg1	mobility					1192:1199	the chains mobility	1181:1199	the chains mobility	1181:1199	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	3	8	theme	CP-MAS	561:566	arg1	NMR					568:570	CP-MAS NMR	561:570	CP-MAS NMR	561:570	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	8	theme	CP-MAS	561:566	arg1	FACE					550:553	FACE	550:553	FACE	550:553	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	2	9	theme	size-fractions	356:369	arg1	parameters					321:330	the digestion kinetic parameters	299:330	the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents	299:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	5	10	theme	structural	926:935	arg1	features					937:944	the granule structural features	914:944	the granule structural features	914:944	The final extent of starch digestion was determined by the granule structural features.					
37230611	7	11	theme	molecular	1161:1169	arg1	order					1171:1175	the molecular order	1157:1175	the molecular order	1157:1175	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	4	12	dep	water	684:688	arg1	protons					701:707	protons	701:707	protons	701:707	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	5	13	theme	granule	918:924	arg1	features					937:944	the granule structural features	914:944	the granule structural features	914:944	The final extent of starch digestion was determined by the granule structural features.					
37230611	1	14	theme	multiple	168:175	arg1	properties					190:199	multiple interrelated properties	168:199	multiple interrelated properties	168:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	0	15	theme	kinetic	96:102	arg1	analysis					104:111	a kinetic analysis	94:111	a kinetic analysis	94:111	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	4	16	theme	macromolecular	769:782	arg1	composition					784:794	the macromolecular composition	765:794	the macromolecular composition of the glucan chains	765:815	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	6	17	theme	accessible	1074:1083	arg1	surface					1085:1091	the accessible surface	1070:1091	the accessible surface for initial binding of α-amylase	1070:1124	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	1	18	theme	interrelated	177:188	arg1	properties					190:199	multiple interrelated properties	168:199	multiple interrelated properties	168:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	1	19	from	determinants	130:141	arg1	properties					190:199	multiple interrelated properties	168:199	multiple interrelated properties	168:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	3	20	theme	time-domain	573:583	arg1	FACE					550:553	FACE	550:553	FACE	550:553	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	20	theme	time-domain	573:583	arg1	NMR					585:587	time-domain NMR	573:587	time-domain NMR	573:587	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	7	21	theme	accessible	1276:1285	arg1	surface					1287:1293	the accessible surface	1272:1293	the accessible surface	1272:1293	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	2	22	theme	wheat	392:396	arg1	starches					398:405	four commercial wheat starches	376:405	four commercial wheat starches with different amylose contents	376:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	4	23	theme	granule	850:856	arg1	ultrastructure					828:841	the ultrastructure	824:841	the ultrastructure of the granule	824:856	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	3	24	dep	techniques	538:547	arg1	DSC…					590:593	DSC…	590:593	DSC…	590:593	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	24	dep	techniques	538:547	arg1	NMR					585:587	time-domain NMR	573:587	time-domain NMR	573:587	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	24	dep	techniques	538:547	arg1	XRD					556:558	XRD	556:558	XRD	556:558	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	24	dep	techniques	538:547	arg1	NMR					568:570	CP-MAS NMR	561:570	CP-MAS NMR	561:570	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	3	24	dep	techniques	538:547	arg1	FACE					550:553	FACE	550:553	FACE	550:553	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	2	25	theme	commercial	381:390	arg1	starches					398:405	four commercial wheat starches	376:405	four commercial wheat starches with different amylose contents	376:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	0	26	theme	structural	28:37	arg1	features					50:57	granule structural or surface features	20:57	granule structural or surface features	20:57	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	8	27	theme	digestion	1415:1423	arg1	studies					1425:1431	starch digestion studies	1408:1431	starch digestion studies	1408:1431	This result confirmed the need to differentiate between the surface and the inner-granule related mechanisms in starch digestion studies.					
37230611	6	28	theme	granule	1051:1057	arg1	size					1059:1062	granule size	1051:1062	granule size	1051:1062	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	0	29	theme	granule	20:26	arg1	features					50:57	granule structural or surface features	20:57	granule structural or surface features	20:57	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	6	30	theme	coefficient	966:976	arg1	dependencies					978:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	2	31	theme	kinetic	313:319	arg1	parameters					321:330	the digestion kinetic parameters	299:330	the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents	299:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	5	32	theme	starch	879:884	arg1	digestion					886:894	starch digestion	879:894	starch digestion	879:894	The final extent of starch digestion was determined by the granule structural features.					
37230611	0	33	theme	surface	42:48	arg1	features					50:57	granule structural or surface features	20:57	granule structural or surface features	20:57	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	6	34	theme	rate	961:964	arg1	dependencies					978:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	6	35	dep	surface	1085:1091	arg1	i.e.					1065:1068	i.e.	1065:1068	i.e.	1065:1068	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	6	36	theme	size	1059:1062	arg1	range					1042:1046	the range	1038:1046	the range of granule size	1038:1062	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	2	37	theme	amylose	422:428	arg1	contents					430:437	different amylose contents	412:437	different amylose contents	412:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	0	38	theme	or	39:40	arg1	features					50:57	granule structural or surface features	20:57	granule structural or surface features	20:57	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	6	39	theme	digestion	951:959	arg1	dependencies					978:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies	947:989	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	6	40	from	dependencies	978:989	arg1	hand					1005:1008	the other hand	995:1008	the other hand	995:1008	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	8	41	theme	starch	1408:1413	arg1	studies					1425:1431	starch digestion studies	1408:1431	starch digestion studies	1408:1431	This result confirmed the need to differentiate between the surface and the inner-granule related mechanisms in starch digestion studies.					
37230611	2	42	theme	different	412:420	arg1	contents					430:437	different amylose contents	412:437	different amylose contents	412:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	3	43	theme	analytic	529:536	arg1	techniques					538:547	analytic techniques	529:547	analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…)	529:594	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	8	44	theme	related	1386:1392	arg1	mechanisms					1394:1403	the inner-granule related mechanisms	1368:1403	the inner-granule related mechanisms	1368:1403	This result confirmed the need to differentiate between the surface and the inner-granule related mechanisms in starch digestion studies.					
37230611	7	45	dep	showed	1150:1155	arg1	accelerating					1227:1238	accelerating	1227:1238	accelerating the digestion rate depending on the accessible surface	1227:1293	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	7	45	dep	showed	1150:1155	arg1	limiting					1215:1222	limiting	1215:1222	limiting	1215:1222	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	4	46	theme	clustering	611:620	arg1	analysis					622:629	A statistical clustering analysis	597:629	A statistical clustering analysis applied on the results	597:652	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	2	47	dep	parameters	321:330	arg1	extent					345:350	final extent	339:350	final extent	339:350	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	2	47	dep	parameters	321:330	arg1	rate					333:336	rate	333:336	rate	333:336	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	6	48	theme	α-amylase	1116:1124	arg1	binding					1105:1111	initial binding	1097:1111	initial binding of α-amylase	1097:1124	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	4	49	theme	glucan	803:808	arg1	chains					810:815	the glucan chains	799:815	the glucan chains	799:815	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	2	50	theme	present	272:278	arg1	study					280:284	The present study	268:284	The present study	268:284	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	2	51	from	starches	398:405	arg1	parameters					321:330	the digestion kinetic parameters	299:330	the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents	299:437	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	2	52	theme	final	339:343	arg1	extent					345:350	final extent	339:350	final extent	339:350	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	2	52	theme	final	339:343	arg1	rate					333:336	rate	333:336	rate	333:336	The present study investigated the digestion kinetic parameters (rate, final extent) of size-fractions from four commercial wheat starches with different amylose contents.					
37230611	4	53	theme	statistical	599:609	arg1	analysis					622:629	A statistical clustering analysis	597:629	A statistical clustering analysis applied on the results	597:652	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	1	54	from	properties	190:199	arg1	determinants					130:141	the determinants	126:141	the determinants of starch digestion from multiple interrelated properties	126:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	1	54	from	properties	190:199	arg1	digestion					153:161	starch digestion	146:161	starch digestion from multiple interrelated properties	146:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	3	55	theme	large	514:518	arg1	range					520:524	a large range	512:524	a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…)	512:594	Each size-fraction was isolated and characterized comprehensively using a large range of analytic techniques (FACE, XRD, CP-MAS NMR, time-domain NMR, DSC…).					
37230611	8	56	theme	inner-granule	1372:1384	arg1	mechanisms					1394:1403	the inner-granule related mechanisms	1368:1403	the inner-granule related mechanisms	1368:1403	This result confirmed the need to differentiate between the surface and the inner-granule related mechanisms in starch digestion studies.					
37230611	4	57	theme	time-domain	721:731	arg1	NMR					733:735	time-domain NMR	721:735	time-domain NMR	721:735	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	0	58	theme	wheat	70:74	arg1	digestion					83:91	the wheat starch digestion	66:91	the wheat starch digestion	66:91	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	5	59	theme	digestion	886:894	arg1	extent					869:874	The final extent	859:874	The final extent of starch digestion	859:894	The final extent of starch digestion was determined by the granule structural features.					
37230611	4	60	theme	chains	810:815	arg1	composition					784:794	the macromolecular composition	765:794	the macromolecular composition of the glucan chains	765:815	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	4	61	theme	water	684:688	arg1	related					754:760	related	754:760	related	754:760	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	4	61	theme	water	684:688	arg1	mobility					672:679	the mobility	668:679	the mobility of water and starch protons measured by time-domain NMR	668:735	A statistical clustering analysis applied on the results revealed that the mobility of water and starch protons measured by time-domain NMR was consistently related to the macromolecular composition of the glucan chains and to the ultrastructure of the granule.					
37230611	5	62	theme	final	863:867	arg1	extent					869:874	The final extent	859:874	The final extent of starch digestion	859:894	The final extent of starch digestion was determined by the granule structural features.					
37230611	1	63	theme	multifactorial	238:251	arg1	analysis					258:265	multifactorial data analysis	238:265	multifactorial data analysis	238:265	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	6	64	theme	initial	1097:1103	arg1	binding					1105:1111	initial binding	1097:1111	initial binding of α-amylase	1097:1124	The digestion rate coefficient dependencies, on the other hand, changed significantly with the range of granule size, i.e. the accessible surface for initial binding of α-amylase.					
37230611	0	65	dep	Determining	0:10	arg1	analysis					104:111	a kinetic analysis	94:111	a kinetic analysis	94:111	Determining whether granule structural or surface features govern the wheat starch digestion, a kinetic analysis.					
37230611	1	66	theme	starch	146:151	arg1	digestion					153:161	starch digestion	146:161	starch digestion from multiple interrelated properties	146:199	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
37230611	7	67	theme	digestion	1244:1252	arg1	rate					1254:1257	the digestion rate	1240:1257	the digestion rate	1240:1257	The study particularly showed the molecular order and the chains mobility predominantly limiting or accelerating the digestion rate depending on the accessible surface.					
37230611	1	68	theme	data	253:256	arg1	analysis					258:265	multifactorial data analysis	238:265	multifactorial data analysis	238:265	Deciphering the determinants of starch digestion from multiple interrelated properties is a challenge that can benefit from multifactorial data analysis.					
35611566	0	0	theme	novel	108:112	arg1	sp					140:141	isolated novel alkalihalophilic Bacillus sp	99:141	isolated novel alkalihalophilic Bacillus sp	99:141	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	13	1	theme	high	1552:1555	arg1	productions					1557:1567	7·7- and 5·4-fold high productions	1534:1567	7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media	1534:1637	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	4	2	theme	enhanced	549:556	arg1	production					558:567	enhanced production	549:567	enhanced production	549:567	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	10	3	theme	significant	1282:1292	arg1	effect					1294:1299	a significant effect	1280:1299	a significant effect on the production of CGTase	1280:1327	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	8	4	theme	.7H2	899:902	arg1	O					904:904	MgSO4 .7H2 O	893:904	MgSO4 .7H2 O	893:904	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	7	5	theme	Central	789:795	arg1	CCD-RSM					844:850	CCD-RSM	844:850	CCD-RSM	844:850	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	5	theme	Central	789:795	arg1	Methodology					831:841	Central Composite Design-Response Surface Methodology	789:841	Central Composite Design-Response Surface Methodology (CCD-RSM)	789:851	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	0	6	theme	isolated	99:106	arg1	sp					140:141	isolated novel alkalihalophilic Bacillus sp	99:141	isolated novel alkalihalophilic Bacillus sp	99:141	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	7	7	theme	β-CGTase	699:706	arg1	production					708:717	The β-CGTase production	695:717	The β-CGTase production	695:717	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	4	8	theme	microbial	488:496	arg1	strain					498:503	an efficient natural microbial strain	467:503	an efficient natural microbial strain	467:503	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	4	9	theme	β-CGTase	441:448	arg1	production					450:459	β-CGTase production	441:459	β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production	441:567	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	4	10	theme	statistical	509:519	arg1	optimization					532:543	statistical production optimization	509:543	statistical production optimization	509:543	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	7	11	theme	Composite	797:805	arg1	CCD-RSM					844:850	CCD-RSM	844:850	CCD-RSM	844:850	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	11	theme	Composite	797:805	arg1	Methodology					831:841	Central Composite Design-Response Surface Methodology	789:841	Central Composite Design-Response Surface Methodology (CCD-RSM)	789:851	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	0	12	theme	Bacillus	131:138	arg1	sp					140:141	isolated novel alkalihalophilic Bacillus sp	99:141	isolated novel alkalihalophilic Bacillus sp	99:141	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	8	13	theme	HPO4	1002:1005	arg1	nonsignificant					1039:1052	nonsignificant	1039:1052	nonsignificant	1039:1052	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	13	theme	HPO4	1002:1005	arg1	concentrations					1007:1020	the soluble starch and K2 HPO4 concentrations	976:1020	the soluble starch and K2 HPO4 concentrations	976:1020	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	10	14	theme	·7H2	1251:1254	arg1	O					1256:1256	MgSO4 ·7H2 O and Na2 CO3	1245:1268	O	1256:1256	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	0	15	theme	alkalihalophilic	114:129	arg1	sp					140:141	isolated novel alkalihalophilic Bacillus sp	99:141	isolated novel alkalihalophilic Bacillus sp	99:141	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	13	16	dep	un-optimized	1584:1595	arg1	media					1633:1637	media	1633:1637	media	1633:1637	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	7	17	theme	Plackett-Burman	756:770	arg1	design					772:777	Plackett-Burman design	756:777	Plackett-Burman design	756:777	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	8	18	theme	K2	999:1000	arg1	nonsignificant					1039:1052	nonsignificant	1039:1052	nonsignificant	1039:1052	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	18	theme	K2	999:1000	arg1	concentrations					1007:1020	the soluble starch and K2 HPO4 concentrations	976:1020	the soluble starch and K2 HPO4 concentrations	976:1020	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	13	19	theme	5·4-fold	1543:1550	arg1	productions					1557:1567	7·7- and 5·4-fold high productions	1534:1567	7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media	1534:1637	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	8	20	theme	Na2	871:873	arg1	CO3					875:877	PBD screening Na2 CO3	857:877	PBD screening Na2 CO3	857:877	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	11	21	theme	Na2	1406:1408	arg1	CO3					1410:1412	Na2 CO3	1406:1412	Na2 CO3 (0·8%)	1406:1419	The production of β-CGTase was enhanced in the presence of peptone (3%) and Na2 CO3 (0·8%).					
35611566	11	21	theme	Na2	1406:1408	arg1	%					1418:1418	0·8%	1415:1418	0·8%	1415:1418	The production of β-CGTase was enhanced in the presence of peptone (3%) and Na2 CO3 (0·8%).					
35611566	2	22	theme	β-cyclodextrin	182:195	arg1	enzyme					244:249	an essential enzyme	231:249	an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD)	231:321	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	2	22	theme	β-cyclodextrin	182:195	arg1	β-CGTase					218:225	β-CGTase	218:225	β-CGTase	218:225	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	2	22	theme	β-cyclodextrin	182:195	arg1	glucosyltransferase					197:215	β-cyclodextrin glucosyltransferase	182:215	β-cyclodextrin glucosyltransferase (β-CGTase)	182:226	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	3	23	contain	has	329:331	arg1	β-CD					324:327	β-CD	324:327	β-CD	324:327	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	3	23	contain	has	329:331	arg2	applications					344:355	widespread applications	333:355	widespread applications	333:355	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	3	24	theme	food	395:398	arg1	industries					400:409	the biomedical, pharmaceutical and food industries	360:409	the biomedical, pharmaceutical and food industries	360:409	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	12	25	theme	CGTase	1422:1427	arg1	production					1429:1438	CGTase production	1422:1438	CGTase production obtained	1422:1447	CGTase production obtained was 156·76 U/ml when optimized using CCD-RSM.					
35611566	8	26	theme	screening	861:869	arg1	CO3					875:877	PBD screening Na2 CO3	857:877	PBD screening Na2 CO3	857:877	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	4	27	theme	present	416:422	arg1	study					424:428	The present study	412:428	The present study	412:428	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	5	28	theme	isolated	574:581	arg1	sp					601:602	The isolated organism Bacillus sp	570:602	The isolated organism Bacillus sp.	570:603	The isolated organism Bacillus sp.					
35611566	3	29	theme	biomedical	364:373	arg1	industries					400:409	the biomedical, pharmaceutical and food industries	360:409	the biomedical, pharmaceutical and food industries	360:409	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	11	30	dep	peptone	1389:1395	arg1	the					1373:1375	the	1373:1375	the	1373:1375	The production of β-CGTase was enhanced in the presence of peptone (3%) and Na2 CO3 (0·8%).					
35611566	11	30	dep	peptone	1389:1395	arg1	presence					1377:1384	presence	1377:1384	presence	1377:1384	The production of β-CGTase was enhanced in the presence of peptone (3%) and Na2 CO3 (0·8%).					
35611566	10	31	from	effect	1294:1299	arg1	production					1308:1317	the production	1304:1317	the production of CGTase	1304:1327	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	5	32	theme	organism	583:590	arg1	sp					601:602	The isolated organism Bacillus sp	570:602	The isolated organism Bacillus sp.	570:603	The isolated organism Bacillus sp.					
35611566	13	33	theme	final	1499:1503	arg1	RSM					1523:1525	RSM	1523:1525	RSM	1523:1525	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	13	33	theme	final	1499:1503	arg1	medium					1515:1520	The final optimized medium	1495:1520	The final optimized medium (RSM)	1495:1526	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	0	34	theme	Medium	0:5	arg1	optimization					7:18	Medium optimization	0:18	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.	0:142	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	7	35	theme	design	772:777	arg1	combination					741:751	a combination	739:751	a combination of Plackett-Burman design (PBD)	739:783	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	35	theme	design	772:777	arg1	CCD-RSM					844:850	CCD-RSM	844:850	CCD-RSM	844:850	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	35	theme	design	772:777	arg1	Methodology					831:841	Central Composite Design-Response Surface Methodology	789:841	Central Composite Design-Response Surface Methodology (CCD-RSM)	789:851	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	35	theme	design	772:777	arg1	PBD					780:782	PBD	780:782	PBD	780:782	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	8	36	located	found	911:915	arg2	O					904:904	MgSO4 .7H2 O	893:904	MgSO4 .7H2 O	893:904	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	36	located	found	911:915	arg2	peptone					881:887	peptone	881:887	peptone	881:887	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	36	located	found	911:915	arg1	CO3					875:877	PBD screening Na2 CO3	857:877	PBD screening Na2 CO3	857:877	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	37	theme	β-CGTase	947:954	arg1	production					956:965	optimal β-CGTase production	939:965	optimal β-CGTase production	939:965	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	13	38	theme	optimized	1505:1513	arg1	RSM					1523:1525	RSM	1523:1525	RSM	1523:1525	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	13	38	theme	optimized	1505:1513	arg1	medium					1515:1520	The final optimized medium	1495:1520	The final optimized medium (RSM)	1495:1526	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	0	39	theme	submerged	24:32	arg1	production					47:56	submerged fermentative production	24:56	submerged fermentative production of β-cyclodextrin glucosyltransferase	24:94	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	10	40	theme	CGTase	1322:1327	arg1	production					1308:1317	the production	1304:1317	the production of CGTase	1304:1327	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	8	41	theme	β-CGTase	1058:1065	arg1	production					1067:1076	β-CGTase production	1058:1076	β-CGTase production	1058:1076	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	42	theme	optimal	939:945	arg1	production					956:965	optimal β-CGTase production	939:965	optimal β-CGTase production	939:965	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	9	43	theme	CCD-RSM	1151:1157	arg1	design					1159:1164	CCD-RSM design	1151:1164	CCD-RSM design	1151:1164	The significant factors obtained after PBD were further optimized using CCD-RSM design.					
35611566	10	44	contain	have	1188:1191	arg2	effect					1219:1224	a significant interaction effect	1193:1224	a significant interaction effect	1193:1224	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	10	44	contain	have	1188:1191	arg1	Peptone					1167:1173	Peptone	1167:1173	Peptone	1167:1173	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	13	45	dep	productions	1557:1567	arg1	compared					1572:1579	compared	1572:1579	compared to un-optimized and one factor at a time production media	1572:1637	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	10	46	theme	Na2	1231:1233	arg1	CO3					1235:1237	Na2 CO3	1231:1237	Na2 CO3	1231:1237	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	8	47	theme	PBD	857:859	arg1	CO3					875:877	PBD screening Na2 CO3	857:877	PBD screening Na2 CO3	857:877	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	0	48	theme	fermentative	34:45	arg1	production					47:56	submerged fermentative production	24:56	submerged fermentative production of β-cyclodextrin glucosyltransferase	24:94	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	6	49	theme	short	636:640	arg1	bacilli					642:648	short bacilli	636:648	short bacilli	636:648	NCIM 5799 was found to be 5 μm short bacilli under FE-SEM and alkalihalophilic in nature.					
35611566	4	50	theme	production	521:530	arg1	optimization					532:543	statistical production optimization	509:543	statistical production optimization	509:543	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	13	51	theme	7·7-	1534:1537	arg1	productions					1557:1567	7·7- and 5·4-fold high productions	1534:1567	7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media	1534:1637	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	8	52	dep	found	911:915	arg1	whereas					968:974	whereas	968:974	whereas	968:974	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	0	53	theme	β-cyclodextrin	61:74	arg1	glucosyltransferase					76:94	β-cyclodextrin glucosyltransferase	61:94	β-cyclodextrin glucosyltransferase	61:94	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	6	54	theme	NCIM	605:608	arg1	5799					610:613	NCIM 5799	605:613	NCIM 5799	605:613	NCIM 5799 was found to be 5 μm short bacilli under FE-SEM and alkalihalophilic in nature.					
35611566	13	55	theme	factor	1605:1610	arg1	production					1622:1631	one factor at a time production	1601:1631	one factor at a time production	1601:1631	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	0	56	theme	glucosyltransferase	76:94	arg1	production					47:56	submerged fermentative production	24:56	submerged fermentative production of β-cyclodextrin glucosyltransferase	24:94	Medium optimization for submerged fermentative production of β-cyclodextrin glucosyltransferase by isolated novel alkalihalophilic Bacillus sp.					
35611566	10	57	theme	interaction	1207:1217	arg1	effect					1219:1224	a significant interaction effect	1193:1224	a significant interaction effect	1193:1224	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	4	58	theme	efficient	470:478	arg1	strain					498:503	an efficient natural microbial strain	467:503	an efficient natural microbial strain	467:503	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	11	59	theme	β-CGTase	1348:1355	arg1	production					1334:1343	The production	1330:1343	The production of β-CGTase	1330:1355	The production of β-CGTase was enhanced in the presence of peptone (3%) and Na2 CO3 (0·8%).					
35611566	8	60	theme	starch	988:993	arg1	nonsignificant					1039:1052	nonsignificant	1039:1052	nonsignificant	1039:1052	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	60	theme	starch	988:993	arg1	concentrations					1007:1020	the soluble starch and K2 HPO4 concentrations	976:1020	the soluble starch and K2 HPO4 concentrations	976:1020	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	6	61	from	alkalihalophilic	667:682	arg1	nature					687:692	nature	687:692	nature	687:692	NCIM 5799 was found to be 5 μm short bacilli under FE-SEM and alkalihalophilic in nature.					
35611566	10	62	theme	significant	1195:1205	arg1	effect					1219:1224	a significant interaction effect	1193:1224	a significant interaction effect	1193:1224	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	6	63	from	nature	687:692	arg1	alkalihalophilic					667:682	alkalihalophilic	667:682	alkalihalophilic	667:682	NCIM 5799 was found to be 5 μm short bacilli under FE-SEM and alkalihalophilic in nature.					
35611566	8	64	theme	soluble	980:986	arg1	nonsignificant					1039:1052	nonsignificant	1039:1052	nonsignificant	1039:1052	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	8	64	theme	soluble	980:986	arg1	concentrations					1007:1020	the soluble starch and K2 HPO4 concentrations	976:1020	the soluble starch and K2 HPO4 concentrations	976:1020	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	10	65	theme	MgSO4	1245:1249	arg1	O					1256:1256	MgSO4 ·7H2 O and Na2 CO3	1245:1268	O	1256:1256	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	3	66	theme	widespread	333:342	arg1	applications					344:355	widespread applications	333:355	widespread applications	333:355	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	2	67	theme	essential	234:242	arg1	enzyme					244:249	an essential enzyme	231:249	an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD)	231:321	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	2	67	theme	essential	234:242	arg1	glucosyltransferase					197:215	β-cyclodextrin glucosyltransferase	182:215	β-cyclodextrin glucosyltransferase (β-CGTase)	182:226	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	9	68	theme	significant	1083:1093	arg1	factors					1095:1101	The significant factors	1079:1101	The significant factors obtained after PBD	1079:1120	The significant factors obtained after PBD were further optimized using CCD-RSM design.					
35611566	5	69	theme	Bacillus	592:599	arg1	sp					601:602	The isolated organism Bacillus sp	570:602	The isolated organism Bacillus sp.	570:603	The isolated organism Bacillus sp.					
35611566	1	70	theme	statistical	160:170	arg1	approach					172:179	statistical approach	160:179	statistical approach	160:179	NCIM 5799 using statistical approach.					
35611566	8	71	theme	MgSO4	893:897	arg1	O					904:904	MgSO4 .7H2 O	893:904	MgSO4 .7H2 O	893:904	On PBD screening Na2 CO3 , peptone and MgSO4 .7H2 O were found to be significant for optimal β-CGTase production, whereas the soluble starch and K2 HPO4 concentrations were found to be nonsignificant for β-CGTase production.					
35611566	13	72	from	time	1617:1620	arg1	factor					1605:1610	one factor	1601:1610	one factor at a time production	1601:1631	The final optimized medium (RSM) shows 7·7- and 5·4-fold high productions as compared to un-optimized and one factor at a time production media.					
35611566	4	73	theme	natural	480:486	arg1	strain					498:503	an efficient natural microbial strain	467:503	an efficient natural microbial strain	467:503	The present study focused on β-CGTase production using an efficient natural microbial strain and statistical production optimization for enhanced production.					
35611566	10	74	theme	Na2	1262:1264	arg1	CO3					1266:1268	MgSO4 ·7H2 O and Na2 CO3	1245:1268	CO3	1266:1268	Peptone was found to have a significant interaction effect with Na2 CO3 , and MgSO4 ·7H2 O and Na2 CO3 exhibited a significant effect on the production of CGTase.					
35611566	7	75	theme	Design-Response	807:821	arg1	CCD-RSM					844:850	CCD-RSM	844:850	CCD-RSM	844:850	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	75	theme	Design-Response	807:821	arg1	Methodology					831:841	Central Composite Design-Response Surface Methodology	789:841	Central Composite Design-Response Surface Methodology (CCD-RSM)	789:851	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	3	76	theme	pharmaceutical	376:389	arg1	industries					400:409	the biomedical, pharmaceutical and food industries	360:409	the biomedical, pharmaceutical and food industries	360:409	β-CD has widespread applications in the biomedical, pharmaceutical and food industries.					
35611566	2	77	theme	starch	288:293	arg1	biotransformation					267:283	the biotransformation	263:283	the biotransformation of starch	263:293	β-cyclodextrin glucosyltransferase (β-CGTase) is an essential enzyme to catalyse the biotransformation of starch into β-cyclodextrins (β-CD).					
35611566	7	78	theme	Surface	823:829	arg1	CCD-RSM					844:850	CCD-RSM	844:850	CCD-RSM	844:850	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35611566	7	78	theme	Surface	823:829	arg1	Methodology					831:841	Central Composite Design-Response Surface Methodology	789:841	Central Composite Design-Response Surface Methodology (CCD-RSM)	789:851	The β-CGTase production was optimized using a combination of Plackett-Burman design (PBD) and Central Composite Design-Response Surface Methodology (CCD-RSM).					
35504415	9	0	theme	neuron-like	1915:1925	arg1	cells					1927:1931	many neuron-like cells	1910:1931	many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes	1910:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	2	1	theme	green	367:371	arg1	scaffolds					395:403	green biomaterial composite scaffolds	367:403	green biomaterial composite scaffolds for nerve cell culture applications	367:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	5	2	contain	containing	1021:1030	arg2	scaffolds					1032:1040	scaffolds	1032:1040	scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1032:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	2	contain	containing	1021:1030	arg1	RuO2					1016:1019	the synthesized RuO2	1000:1019	the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1000:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	3	3	theme	green	552:556	arg1	RuO2					575:578	RuO2	575:578	RuO2	575:578	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	3	3	theme	green	552:556	arg1	oxide					568:572	green ruthenium oxide	552:572	green ruthenium oxide (RuO2)	552:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	1	4	theme	substrates	289:298	arg1	development					260:270	the development	256:270	the development of biocompatible substrates for cells growth	256:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	7	5	theme	scaffolds	1450:1458	arg1	properties					1421:1430	mechanical properties	1410:1430	mechanical properties of the fabricated scaffolds (up to 8.55 MPa)	1410:1475	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	9	6	theme	cell	1947:1950	arg1	bodies					1952:1957	apparent cell bodies	1938:1957	apparent cell bodies	1938:1957	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	4	7	theme	calorimetry	710:720	arg1	analyses					728:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses	659:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses	659:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	6	8	theme	variant	1276:1282	arg1	features					1284:1291	variant features	1276:1291	variant features attributed to the concentration of RuO2 NPs in the scaffold	1276:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	6	9	theme	electron	1189:1196	arg1	SEM					1210:1212	SEM	1210:1212	SEM	1210:1212	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	6	9	theme	electron	1189:1196	arg1	microscopy					1198:1207	Scanning electron microscopy	1180:1207	Scanning electron microscopy (SEM) results	1180:1221	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	6	10	theme	scaffolds	1261:1269	arg1	structure					1244:1252	a 3D porous structure	1232:1252	a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold	1232:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	9	11	theme	few	1974:1976	arg1	processes					1997:2005	possessing few short neurite-like processes	1963:2005	possessing few short neurite-like processes	1963:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	5	12	theme	plant	1100:1104	arg1	extract					1106:1112	the natural plant extract	1088:1112	the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1088:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	12	theme	plant	1100:1104	arg1	Aspalathuslinearis					1115:1132	Aspalathuslinearis	1115:1132	Aspalathuslinearis	1115:1132	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	3	13	theme	ruthenium	558:566	arg1	RuO2					575:578	RuO2	575:578	RuO2	575:578	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	3	13	theme	ruthenium	558:566	arg1	oxide					568:572	green ruthenium oxide	552:572	green ruthenium oxide (RuO2)	552:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	9	14	theme	neurite-like	1984:1995	arg1	processes					1997:2005	possessing few short neurite-like processes	1963:2005	possessing few short neurite-like processes	1963:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	4	15	theme	differential	688:699	arg1	calorimetry					710:720	differential scanning calorimetry	688:720	differential scanning calorimetry (DSC)	688:726	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	4	15	theme	differential	688:699	arg1	DSC					723:725	DSC	723:725	DSC	723:725	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	10	16	theme	glycine	2033:2039	arg1	presence					2012:2019	The presence	2008:2019	The presence of RuO2 and glycine	2008:2039	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	10	16	theme	glycine	2033:2039	arg1	due					2045:2047	due	2045:2047	due	2045:2047	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	3	17	theme	techniques	647:656	arg1	combination					622:632	a combination	620:632	a combination of different techniques	620:656	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	7	18	dep	recorded	1383:1390	arg1	correlated					1493:1502	correlated	1493:1502	proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold	1478:1573	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	10	19	theme	RuO2	2024:2027	arg1	presence					2012:2019	The presence	2008:2019	The presence of RuO2 and glycine	2008:2039	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	10	19	theme	RuO2	2024:2027	arg1	due					2045:2047	due	2045:2047	due	2045:2047	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	6	20	theme	NPs	1333:1335	arg1	concentration					1311:1323	the concentration	1307:1323	the concentration of RuO2 NPs in the scaffold	1307:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	1	21	from	moment	217:222	arg1	topics					178:183	the most challenging topics	157:183	the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth	157:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	1	21	from	moment	217:222	arg1	medicine					201:208	regenerative medicine	188:208	regenerative medicine	188:208	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	6	22	theme	3D	1234:1235	arg1	structure					1244:1252	a 3D porous structure	1232:1252	a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold	1232:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	5	23	theme	vibrational	979:989	arg1	bands					991:995	the vibrational bands	975:995	the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	975:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	7	24	theme	compressive	1358:1368	arg1	results					1375:1381	The compressive test results	1354:1381	The compressive test results	1354:1381	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	5	25	theme	nanoparticles	1149:1161	arg1	synthesis					1169:1177	RuO2 nanoparticles (NPs) synthesis	1144:1177	RuO2 nanoparticles (NPs) synthesis	1144:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	1	26	theme	challenging	166:176	arg1	topics					178:183	the most challenging topics	157:183	the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth	157:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	1	27	from	topics	178:183	arg1	medicine					201:208	regenerative medicine	188:208	regenerative medicine	188:208	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	1	27	from	topics	178:183	arg1	moment					217:222	the moment	213:222	the moment	213:222	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	9	28	theme	cells	1813:1817	arg1	attachments					1819:1829	the impressive cells attachments	1798:1829	the impressive cells attachments	1798:1829	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	4	29	theme	peak	817:820	arg1	intensity					822:830	the peak intensity	813:830	the peak intensity of the fabricated scaffolds	813:858	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	2	30	theme	culture	420:426	arg1	applications					428:439	nerve cell culture applications	409:439	nerve cell culture applications	409:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	9	31	theme	scaffold	1860:1867	arg1	surfaces					1869:1876	the scaffold surfaces	1856:1876	the scaffold surfaces	1856:1876	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	5	32	theme	RuO2	1016:1019	arg1	bands					991:995	the vibrational bands	975:995	the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	975:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	2	33	theme	nerve	409:413	arg1	applications					428:439	nerve cell culture applications	409:439	nerve cell culture applications	409:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	4	34	theme	noticeable	790:799	arg1	decrease					801:808	noticeable decrease	790:808	noticeable decrease in the peak intensity of the fabricated scaffolds	790:858	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	3	35	theme	composite	503:511	arg1	scaffolds					449:457	Hybrid scaffolds	442:457	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2)	442:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	0	36	theme	hydroxyethyl	20:31	arg1	composite					56:64	hydroxyethyl cellulose/glycine/RuO2 composite	20:64	hydroxyethyl cellulose/glycine/RuO2 composite	20:64	Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite scaffolds for neural-like cells.					
35504415	1	37	theme	most	161:164	arg1	topics					178:183	the most challenging topics	157:183	the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth	157:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	3	38	theme	Hybrid	442:447	arg1	scaffolds					449:457	Hybrid scaffolds	442:457	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2)	442:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	5	39	dep	transform	906:914	arg1	infrared					916:923	infrared	916:923	transform infrared spectroscopy (FTIR) tests	906:949	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	3	40	theme	HEC/Gly	494:500	arg1	composite					503:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite	462:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2)	462:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	0	41	theme	composite	56:64	arg1	Biocompatibility					0:15	Biocompatibility	0:15	Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite	0:64	Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite scaffolds for neural-like cells.					
35504415	7	42	theme	HEC/Gly	1548:1554	arg1	scaffold					1566:1573	HEC/Gly composite scaffold	1548:1573	HEC/Gly composite scaffold	1548:1573	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	11	43	theme	neural-like	2233:2243	arg1	cells					2245:2249	neural-like cells	2233:2249	neural-like cells	2233:2249	Therefore, we conclude that these scaffolds are promising for accommodation and growth of neural-like cells.					
35504415	5	44	theme	functional	1067:1076	arg1	extract					1106:1112	the natural plant extract	1088:1112	the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1088:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	44	theme	functional	1067:1076	arg1	groups					1078:1083	the functional groups	1063:1083	the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1063:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	44	theme	functional	1067:1076	arg1	Aspalathuslinearis					1115:1132	Aspalathuslinearis	1115:1132	Aspalathuslinearis	1115:1132	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	10	45	theme	regenerative	2121:2132	arg1	effects					2134:2140	their cytoprotective and regenerative effects	2096:2140	their cytoprotective and regenerative effects	2096:2140	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	8	46	theme	composite	1621:1629	arg1	scaffolds					1631:1639	the composite scaffolds	1617:1639	the composite scaffolds doped with 1 and 2 ml of RuO2	1617:1669	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	7	47	theme	RuO2	1522:1525	arg1	concentration					1531:1543	the RuO2 NPs concentration	1518:1543	the RuO2 NPs concentration	1518:1543	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	10	48	theme	cytoprotective	2102:2115	arg1	effects					2134:2140	their cytoprotective and regenerative effects	2096:2140	their cytoprotective and regenerative effects	2096:2140	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	4	49	theme	fabricated	839:848	arg1	scaffolds					850:858	the fabricated scaffolds	835:858	the fabricated scaffolds	835:858	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	3	50	theme	oxide	568:572	arg1	concentrations					534:547	different concentrations	524:547	different concentrations of green ruthenium oxide (RuO2)	524:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	8	51	theme	proliferation	1696:1708	arg1	%					1738:1738	152.2 and 135.6%	1723:1738	152.2 and 135.6%	1723:1738	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	8	51	theme	proliferation	1696:1708	arg1	percentages					1710:1720	the highest proliferation percentages	1684:1720	the highest proliferation percentages (152.2 and 135.6%)	1684:1739	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	6	52	from	concentration	1311:1323	arg1	scaffold					1344:1351	the scaffold	1340:1351	the scaffold	1340:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	9	53	theme	many	1910:1913	arg1	cells					1927:1931	many neuron-like cells	1910:1931	many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes	1910:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	4	54	theme	diffraction	666:676	arg1	analyses					728:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses	659:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses	659:735	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	2	55	theme	biomaterial	373:383	arg1	scaffolds					395:403	green biomaterial composite scaffolds	367:403	green biomaterial composite scaffolds for nerve cell culture applications	367:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	6	56	with	scaffolds	1261:1269	arg1	features					1284:1291	variant features	1276:1291	variant features attributed to the concentration of RuO2 NPs in the scaffold	1276:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	9	57	theme	cells	1927:1931	arg1	presence					1898:1905	the presence	1894:1905	the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes	1894:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	1	58	theme	biocompatible	275:287	arg1	substrates					289:298	biocompatible substrates	275:298	biocompatible substrates for cells growth	275:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	9	59	theme	apparent	1938:1945	arg1	bodies					1952:1957	apparent cell bodies	1938:1957	apparent cell bodies	1938:1957	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	8	60	theme	RuO2	1666:1669	arg1	1					1652:1652	1	1652:1652	1	1652:1652	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	8	60	theme	RuO2	1666:1669	arg1	RuO2					1666:1669	RuO2	1666:1669	RuO2	1666:1669	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	1	61	theme	regenerative	188:199	arg1	medicine					201:208	regenerative medicine	188:208	regenerative medicine	188:208	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	6	62	theme	microscopy	1198:1207	arg1	results					1215:1221	Scanning electron microscopy (SEM) results	1180:1221	Scanning electron microscopy (SEM) results	1180:1221	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	4	63	theme	scanning	701:708	arg1	calorimetry					710:720	differential scanning calorimetry	688:720	differential scanning calorimetry (DSC)	688:726	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	4	63	theme	scanning	701:708	arg1	DSC					723:725	DSC	723:725	DSC	723:725	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	4	64	theme	pure	884:887	arg1	glycine					889:895	pure glycine	884:895	pure glycine	884:895	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	7	65	theme	fabricated	1439:1448	arg1	scaffolds					1450:1458	the fabricated scaffolds	1435:1458	the fabricated scaffolds (up to 8.55 MPa)	1435:1475	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	9	66	theme	possessing	1963:1972	arg1	processes					1997:2005	possessing few short neurite-like processes	1963:2005	possessing few short neurite-like processes	1963:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	6	67	theme	Scanning	1180:1187	arg1	SEM					1210:1212	SEM	1210:1212	SEM	1210:1212	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	6	67	theme	Scanning	1180:1187	arg1	microscopy					1198:1207	Scanning electron microscopy	1180:1207	Scanning electron microscopy (SEM) results	1180:1221	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	9	68	theme	short	1978:1982	arg1	processes					1997:2005	possessing few short neurite-like processes	1963:2005	possessing few short neurite-like processes	1963:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	5	69	theme	extract	1106:1112	arg1	extract					1106:1112	the natural plant extract	1088:1112	the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1088:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	69	theme	extract	1106:1112	arg1	groups					1078:1083	the functional groups	1063:1083	the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1063:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	69	theme	extract	1106:1112	arg1	Aspalathuslinearis					1115:1132	Aspalathuslinearis	1115:1132	Aspalathuslinearis	1115:1132	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	3	70	theme	different	637:645	arg1	techniques					647:656	different techniques	637:656	different techniques	637:656	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	7	71	theme	mechanical	1410:1419	arg1	properties					1421:1430	mechanical properties	1410:1430	mechanical properties of the fabricated scaffolds (up to 8.55 MPa)	1410:1475	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	7	72	dep	scaffolds	1450:1458	arg1	up					1461:1462	up	1461:1462	up to 8.55 MPa	1461:1474	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	6	73	theme	porous	1237:1242	arg1	structure					1244:1252	a 3D porous structure	1232:1252	a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold	1232:1351	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	4	74	theme	crystalline	746:756	arg1	nature					758:763	a crystalline nature	744:763	a crystalline nature for all the samples	744:783	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	6	75	theme	RuO2	1328:1331	arg1	NPs					1333:1335	RuO2 NPs	1328:1335	RuO2 NPs	1328:1335	Scanning electron microscopy (SEM) results revealed a 3D porous structure of the scaffolds with variant features attributed to the concentration of RuO2 NPs in the scaffold.					
35504415	5	76	theme	natural	1092:1098	arg1	extract					1106:1112	the natural plant extract	1088:1112	the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1088:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	76	theme	natural	1092:1098	arg1	Aspalathuslinearis					1115:1132	Aspalathuslinearis	1115:1132	Aspalathuslinearis	1115:1132	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	77	theme	spectroscopy	925:936	arg1	tests					945:949	spectroscopy (FTIR) tests	925:949	spectroscopy (FTIR) tests	925:949	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	9	78	theme	SEM	1775:1777	arg1	analyses					1779:1786	the SEM analyses	1771:1786	the SEM analyses	1771:1786	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	7	79	theme	test	1370:1373	arg1	results					1375:1381	The compressive test results	1354:1381	The compressive test results	1354:1381	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	1	80	theme	topics	178:183	arg1	topics					178:183	the most challenging topics	157:183	the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth	157:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	1	80	theme	topics	178:183	arg1	one					150:152	one	150:152	one	150:152	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	10	81	theme	due	2089:2091	arg1	biocompatibility					2072:2087	their extraordinary biocompatibility	2052:2087	their extraordinary biocompatibility due to their cytoprotective and regenerative effects	2052:2140	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	9	82	theme	impressive	1802:1811	arg1	attachments					1819:1829	the impressive cells attachments	1798:1829	the impressive cells attachments	1798:1829	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	10	83	theme	extraordinary	2058:2070	arg1	biocompatibility					2072:2087	their extraordinary biocompatibility	2052:2087	their extraordinary biocompatibility due to their cytoprotective and regenerative effects	2052:2140	The presence of RuO2 and glycine was due to their extraordinary biocompatibility due to their cytoprotective and regenerative effects.					
35504415	4	84	from	decrease	801:808	arg1	intensity					822:830	the peak intensity	813:830	the peak intensity of the fabricated scaffolds	813:858	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	5	85	theme	synthesized	1004:1014	arg1	RuO2					1016:1019	the synthesized RuO2	1000:1019	the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	1000:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	2	86	theme	cell	415:418	arg1	applications					428:439	nerve cell culture applications	409:439	nerve cell culture applications	409:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	5	87	theme	RuO2	1144:1147	arg1	NPs					1164:1166	NPs	1164:1166	NPs	1164:1166	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	87	theme	RuO2	1144:1147	arg1	nanoparticles					1149:1161	RuO2 nanoparticles	1144:1161	RuO2 nanoparticles (NPs) synthesis	1144:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	5	88	from	increase	963:970	arg1	bands					991:995	the vibrational bands	975:995	the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis	975:1177	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	1	89	theme	scaffolds	114:122	arg1	Fabrication					99:109	Fabrication	99:109	Fabrication of scaffolds for nerve regeneration	99:145	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	8	90	theme	biocompatibility	1580:1595	arg1	tests					1597:1601	Our biocompatibility tests	1576:1601	Our biocompatibility tests	1576:1601	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	3	91	theme	hydroxyethyl	462:473	arg1	composite					503:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite	462:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2)	462:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	0	92	theme	cellulose/glycine/RuO2	33:54	arg1	composite					56:64	hydroxyethyl cellulose/glycine/RuO2 composite	20:64	hydroxyethyl cellulose/glycine/RuO2 composite	20:64	Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite scaffolds for neural-like cells.					
35504415	1	93	theme	cells	304:308	arg1	growth					310:315	cells growth	304:315	cells growth	304:315	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	1	94	theme	nerve	128:132	arg1	regeneration					134:145	nerve regeneration	128:145	nerve regeneration	128:145	Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth.					
35504415	7	95	from	enhancement	1395:1405	arg1	properties					1421:1430	mechanical properties	1410:1430	mechanical properties of the fabricated scaffolds (up to 8.55 MPa)	1410:1475	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	2	96	theme	scaffolds	395:403	arg1	development					352:362	the development	348:362	the development of green biomaterial composite scaffolds for nerve cell culture applications	348:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
35504415	3	97	theme	cellulose/glycine	475:491	arg1	composite					503:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite	462:511	hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2)	462:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	4	98	theme	scaffolds	850:858	arg1	intensity					822:830	the peak intensity	813:830	the peak intensity of the fabricated scaffolds	813:858	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	0	99	theme	neural-like	80:90	arg1	cells					92:96	neural-like cells	80:96	neural-like cells	80:96	Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite scaffolds for neural-like cells.					
35504415	7	100	theme	composite	1556:1564	arg1	scaffold					1566:1573	HEC/Gly composite scaffold	1548:1573	HEC/Gly composite scaffold	1548:1573	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	11	101	theme	cells	2245:2249	arg1	growth					2223:2228	growth	2223:2228	growth	2223:2228	Therefore, we conclude that these scaffolds are promising for accommodation and growth of neural-like cells.					
35504415	11	101	theme	cells	2245:2249	arg1	accommodation					2205:2217	accommodation	2205:2217	accommodation	2205:2217	Therefore, we conclude that these scaffolds are promising for accommodation and growth of neural-like cells.					
35504415	5	102	dep	Fourier	898:904	arg1	transform					906:914	transform	906:914	transform infrared spectroscopy (FTIR) tests	906:949	Fourier transform infrared spectroscopy (FTIR) tests revealed an increase in the vibrational bands of the synthesized RuO2 containing scaffolds which are related to the functional groups of the natural plant extract (Aspalathuslinearis) used for RuO2 nanoparticles (NPs) synthesis.					
35504415	8	103	theme	highest	1688:1694	arg1	%					1738:1738	152.2 and 135.6%	1723:1738	152.2 and 135.6%	1723:1738	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	8	103	theme	highest	1688:1694	arg1	percentages					1710:1720	the highest proliferation percentages	1684:1720	the highest proliferation percentages (152.2 and 135.6%)	1684:1739	Our biocompatibility tests revealed that the composite scaffolds doped with 1 and 2 ml of RuO2 demonstrated the highest proliferation percentages (152.2 and 135.6%) compared to control.					
35504415	4	104	theme	X-rays	659:664	arg1	XRD					679:681	XRD	679:681	XRD	679:681	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	4	104	theme	X-rays	659:664	arg1	diffraction					666:676	X-rays diffraction	659:676	X-rays diffraction (XRD)	659:682	X-rays diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed a crystalline nature for all the samples with noticeable decrease in the peak intensity of the fabricated scaffolds as compared to that for pure glycine.					
35504415	3	105	theme	different	524:532	arg1	concentrations					534:547	different concentrations	524:547	different concentrations of green ruthenium oxide (RuO2)	524:579	Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO2) were synthesized and characterized via a combination of different techniques.					
35504415	7	106	theme	NPs	1527:1529	arg1	concentration					1531:1543	the RuO2 NPs concentration	1518:1543	the RuO2 NPs concentration	1518:1543	The compressive test results recorded an enhancement in mechanical properties of the fabricated scaffolds (up to 8.55 MPa), proportionally correlated to increasing the RuO2 NPs concentration in HEC/Gly composite scaffold.					
35504415	9	107	with	cells	1927:1931	arg1	bodies					1952:1957	apparent cell bodies	1938:1957	apparent cell bodies	1938:1957	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	9	107	with	cells	1927:1931	arg1	processes					1997:2005	possessing few short neurite-like processes	1963:2005	possessing few short neurite-like processes	1963:2005	Finally, the SEM analyses confirmed the impressive cells attachments and differentiation onto the scaffold surfaces as evidenced by the presence of many neuron-like cells with apparent cell bodies and possessing few short neurite-like processes.					
35504415	2	108	theme	composite	385:393	arg1	scaffolds					395:403	green biomaterial composite scaffolds	367:403	green biomaterial composite scaffolds for nerve cell culture applications	367:439	This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications.					
36456598	6	0	theme	%	724:724	arg1	efficiency					726:735	89.2% efficiency	720:735	89.2% efficiency	720:735	By doping BaTiO3, acid red 151 and acid blue 113 achieved 86.7% and 89.2% efficiency, respectively.					
36456598	4	1	theme	%	487:487	arg1	%					496:496	60.9% to 61.3% and 64.4%	483:506	%	496:496	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	4	2	theme	blue	428:431	arg1	acid					423:426	acid blue 113	423:435	acid blue 113	423:435	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	9	3	theme	piezo-catalytic	966:980	arg1	activity					982:989	the piezo-catalytic activity	962:989	the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst	962:1022	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	9	4	theme	AB113	1099:1103	arg1	degradation					1084:1094	the degradation	1080:1094	the degradation of AB113	1080:1103	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	8	5	theme	red	866:868	arg1	acid					861:864	acid red 151	861:872	acid red 151	861:872	These strategies improved degradation efficiency for acid red 151 and acid blue 113 to 92.9% and 93.3%, respectively.					
36456598	7	6	mod	modified	785:792	arg3	sucrose					799:805	sucrose	799:805	sucrose	799:805	Finally, the nanostructures were modified with sucrose.					
36456598	7	6	mod	modified	785:792	arg1	nanostructures					765:778	the nanostructures	761:778	the nanostructures	761:778	Finally, the nanostructures were modified with sucrose.					
36456598	0	7	dep	Fe	78:79	arg1	BaTiO3					91:96	BaTiO3	91:96	BaTiO3	91:96	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	0	7	dep	Fe	78:79	arg1	S					89:89	S	89:89	S	89:89	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	5	8	theme	BaTiO3	594:599	arg1	composite					571:579	the composite	567:579	the composite of BaSO4 and BaTiO3	567:599	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	5	8	theme	BaTiO3	594:599	arg1	BaTiO3					594:599	BaTiO3	594:599	BaTiO3	594:599	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	5	8	theme	BaTiO3	594:599	arg1	BaSO4					584:588	BaSO4	584:588	BaSO4	584:588	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	2	9	theme	piezocatalytic	314:327	arg1	activity					329:336	the piezocatalytic activity	310:336	the piezocatalytic activity of BaSO4	310:345	Three techniques are employed in this study to enhance the piezocatalytic activity of BaSO4.					
36456598	4	10	theme	red	411:413	arg1	acid					406:409	acid red 151	406:417	acid red 151	406:417	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	0	11	theme	water	129:133	arg1	purification					135:146	water purification	129:146	water purification	129:146	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	9	12	theme	m-S-BaSO4-BaTiO3	998:1013	arg1	catalyst					1015:1022	the m-S-BaSO4-BaTiO3 catalyst	994:1022	the m-S-BaSO4-BaTiO3 catalyst	994:1022	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	0	13	theme	piezocatalytic	6:19	arg1	activity					21:28	piezocatalytic activity	6:28	piezocatalytic activity of BaSO4	6:37	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	8	14	theme	blue	883:886	arg1	acid					878:881	acid blue 113	878:890	acid blue 113	878:890	These strategies improved degradation efficiency for acid red 151 and acid blue 113 to 92.9% and 93.3%, respectively.					
36456598	9	15	theme	catalyst	1015:1022	arg1	activity					982:989	the piezo-catalytic activity	962:989	the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst	962:1022	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	6	16	theme	89.2	720:723	arg1	%					724:724	%	724:724	%	724:724	By doping BaTiO3, acid red 151 and acid blue 113 achieved 86.7% and 89.2% efficiency, respectively.					
36456598	8	17	theme	degradation	834:844	arg1	efficiency					846:855	degradation efficiency	834:855	degradation efficiency	834:855	These strategies improved degradation efficiency for acid red 151 and acid blue 113 to 92.9% and 93.3%, respectively.					
36456598	3	18	theme	first	352:356	arg1	method					358:363	The first method	348:363	The first method	348:363	The first method involves coupling BaSO4 with BaTiO3.					
36456598	4	19	dep	acid	406:409	arg1	rates					453:457	decontamination rates	437:457	decontamination rates	437:457	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	4	19	dep	acid	406:409	arg1	The					402:404	The	402:404	The	402:404	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	0	20	dep	BaTiO3	59:64	arg1	Fe					78:79	Fe	78:79	Fe	78:79	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	1	21	theme	decontamination	207:221	arg1	efficiency					193:202	the efficiency	189:202	the efficiency of decontamination	189:221	The purpose of this study is to improve the efficiency of decontamination using BaSO4 as a piezocatalyst.					
36456598	3	22	with	BaSO4	383:387	arg1	BaTiO3					394:399	BaTiO3	394:399	BaTiO3	394:399	The first method involves coupling BaSO4 with BaTiO3.					
36456598	6	23	theme	blue	692:695	arg1	acid					687:690	acid blue 113	687:699	acid blue 113	687:699	By doping BaTiO3, acid red 151 and acid blue 113 achieved 86.7% and 89.2% efficiency, respectively.					
36456598	2	24	theme	BaSO4	341:345	arg1	activity					329:336	the piezocatalytic activity	310:336	the piezocatalytic activity of BaSO4	310:345	Three techniques are employed in this study to enhance the piezocatalytic activity of BaSO4.					
36456598	3	25	theme	coupling	374:381	arg1	BaSO4					383:387	coupling BaSO4	374:387	coupling BaSO4 with BaTiO3	374:399	The first method involves coupling BaSO4 with BaTiO3.					
36456598	0	26	theme	BaSO4	33:37	arg1	activity					21:28	piezocatalytic activity	6:28	piezocatalytic activity of BaSO4	6:37	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	4	27	theme	decontamination	437:451	arg1	rates					453:457	decontamination rates	437:457	decontamination rates	437:457	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	5	28	theme	BaSO4	584:588	arg1	composite					571:579	the composite	567:579	the composite of BaSO4 and BaTiO3	567:599	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	5	28	theme	BaSO4	584:588	arg1	BaTiO3					594:599	BaTiO3	594:599	BaTiO3	594:599	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	5	28	theme	BaSO4	584:588	arg1	BaSO4					584:588	BaSO4	584:588	BaSO4	584:588	Additionally, the composite of BaSO4 and BaTiO3 was doped with copper, iron, sulfur, and nitrogen.					
36456598	9	29	theme	significant	1039:1049	arg1	loss					1051:1054	a significant loss	1037:1054	a significant loss after five recycles for the degradation of AB113	1037:1103	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	0	30	dep	coupling	42:49	arg1	it					51:52	it	51:52	it	51:52	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	6	31	theme	red	675:677	arg1	acid					670:673	acid red 151	670:681	acid red 151	670:681	By doping BaTiO3, acid red 151 and acid blue 113 achieved 86.7% and 89.2% efficiency, respectively.					
36456598	9	32	theme	reusability	930:940	arg1	results					942:948	The reusability results	926:948	The reusability results	926:948	The reusability results showed that the piezo-catalytic activity of the m-S-BaSO4-BaTiO3 catalyst did not show a significant loss after five recycles for the degradation of AB113.					
36456598	4	33	dep	%	496:496	arg1	to					489:490	to	489:490	to	489:490	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	0	34	with	coupling	42:49	arg1	Cu					67:68	Cu	67:68	Cu	67:68	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	0	34	with	coupling	42:49	arg1	BaTiO3					59:64	BaTiO3	59:64	BaTiO3	59:64	Boost piezocatalytic activity of BaSO4 by coupling it with BaTiO3, Cu:BaTiO3, Fe:BaTiO3, S:BaTiO3 and modify them by sucrose for water purification.					
36456598	4	35	theme	strategy	543:550	arg1	result					528:533	a result	526:533	a result of this strategy	526:550	The acid red 151 and acid blue 113 decontamination rates improved from 56.7% and 60.9% to 61.3% and 64.4%, respectively, as a result of this strategy.					
36456598	1	36	theme	study	169:173	arg1	purpose					153:159	The purpose	149:159	The purpose of this study	149:173	The purpose of this study is to improve the efficiency of decontamination using BaSO4 as a piezocatalyst.					
36364130	1	0	theme	particleboards	151:164	arg1	properties					127:136	the properties	123:136	the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders	123:236	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	7	1	dep	%	894:894	arg1	to					886:887	to	886:887	to	886:887	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	9	2	theme	physical	1018:1025	arg1	properties					1042:1051	physical and mechanical properties	1018:1051	physical and mechanical properties that comply with European standards for use in building construction	1018:1120	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	6	3	theme	N/mm2	755:759	arg1	MOE					742:744	MOE	742:744	MOE	742:744	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	3	theme	N/mm2	755:759	arg1	elasticity					730:739	elasticity	730:739	elasticity (MOE) of 3196 N/mm2	730:759	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	9	4	theme	giant	953:957	arg1	particleboards					978:991	giant reed-gypsum-starch particleboards	953:991	giant reed-gypsum-starch particleboards	953:991	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	2	5	theme	different	345:353	arg1	starch					366:371	starch	366:371	starch	366:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	5	theme	different	345:353	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	5	theme	different	345:353	arg1	amounts					355:361	different amounts	345:361	different amounts of starch	345:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	6	6	theme	N/mm2	809:813	arg1	strength					787:794	an internal bounding strength	766:794	an internal bounding strength (IB) of 0.62 N/mm2	766:813	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	6	theme	N/mm2	809:813	arg1	IB					797:798	IB	797:798	IB	797:798	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	6	theme	N/mm2	809:813	arg1	modulus					677:683	a modulus	675:683	a modulus of rupture (MOR) of 17.5 N/mm2	675:714	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	6	theme	N/mm2	809:813	arg1	modulus					719:725	a modulus	717:725	a modulus of elasticity (MOE) of 3196 N/mm2	717:759	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	9	7	theme	building	1100:1107	arg1	construction					1109:1120	building construction	1100:1120	building construction	1100:1120	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	9	8	theme	reed-gypsum-starch	959:976	arg1	particleboards					978:991	giant reed-gypsum-starch particleboards	953:991	giant reed-gypsum-starch particleboards	953:991	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	4	9	theme	°C	459:460	arg1	temperature					440:450	a temperature	438:450	a temperature of 110 °C	438:460	The mix was pressed at a temperature of 110 °C with a pressure of 2.6 MPa for 1, 2, and 3 h.					
36364130	6	10	theme	rupture	688:694	arg1	strength					787:794	an internal bounding strength	766:794	an internal bounding strength (IB) of 0.62 N/mm2	766:813	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	10	theme	rupture	688:694	arg1	IB					797:798	IB	797:798	IB	797:798	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	10	theme	rupture	688:694	arg1	modulus					677:683	a modulus	675:683	a modulus of rupture (MOR) of 17.5 N/mm2	675:714	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	10	theme	rupture	688:694	arg1	modulus					719:725	a modulus	717:725	a modulus of elasticity (MOE) of 3196 N/mm2	717:759	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	7	11	from	h	846:846	arg1	TS					836:837	TS	836:837	TS	836:837	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	7	11	from	h	846:846	arg1	swelling					826:833	Thickness swelling	816:833	Thickness swelling (TS) at 24 h of the panels	816:860	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	6	12	theme	%	602:602	arg1	starch					604:609	% starch	602:609	% starch	602:609	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	3	13	theme	Giant	374:378	arg1	particles					385:393	Giant reed particles	374:393	Giant reed particles used	374:398	Giant reed particles used were ≤0.25 mm.					
36364130	3	14	theme	reed	380:383	arg1	particles					385:393	Giant reed particles	374:393	Giant reed particles used	374:398	Giant reed particles used were ≤0.25 mm.					
36364130	5	15	theme	longer	561:566	arg1	times					568:572	longer times	561:572	longer times	561:572	The results showed that the boards manufactured with longer times in the press and with 10 wt.					
36364130	2	16	theme	starch	366:371	arg1	amounts					355:361	different amounts	345:361	different amounts of starch	345:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	16	theme	starch	366:371	arg1	starch					366:371	starch	366:371	starch	366:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	16	theme	starch	366:371	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	16	theme	starch	366:371	arg1	ratio					296:300	a 10:2 weight ratio	282:300	a 10:2 weight ratio of giant reed/gypsum plaster particles	282:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	0	17	theme	Properties	18:27	arg1	Assessment					0:9	Assessment	0:9	Assessment of the Properties of Giant Reed Particleboards	0:56	Assessment of the Properties of Giant Reed Particleboards Agglomerated with Gypsum Plaster and Starch.					
36364130	2	18	theme	weight	289:294	arg1	ratio					296:300	a 10:2 weight ratio	282:300	a 10:2 weight ratio of giant reed/gypsum plaster particles	282:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	1	19	theme	giant	185:189	arg1	reed					191:194	giant reed	185:194	giant reed with gypsum plaster and starch as binders	185:236	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	2	20	theme	10:2	284:287	arg1	ratio					296:300	a 10:2 weight ratio	282:300	a 10:2 weight ratio of giant reed/gypsum plaster particles	282:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	1	21	theme	reed	191:194	arg1	mix					178:180	a mix	176:180	a mix of giant reed with gypsum plaster and starch as binders	176:236	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	0	22	theme	Giant	32:36	arg1	Particleboards					43:56	Giant Reed Particleboards	32:56	Giant Reed Particleboards	32:56	Assessment of the Properties of Giant Reed Particleboards Agglomerated with Gypsum Plaster and Starch.					
36364130	7	23	theme	panels	855:860	arg1	h					846:846	24 h	843:846	24 h of the panels	843:860	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	6	24	theme	elasticity	730:739	arg1	strength					787:794	an internal bounding strength	766:794	an internal bounding strength (IB) of 0.62 N/mm2	766:813	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	24	theme	elasticity	730:739	arg1	IB					797:798	IB	797:798	IB	797:798	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	24	theme	elasticity	730:739	arg1	modulus					677:683	a modulus	675:683	a modulus of rupture (MOR) of 17.5 N/mm2	675:714	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	24	theme	elasticity	730:739	arg1	modulus					719:725	a modulus	717:725	a modulus of elasticity (MOE) of 3196 N/mm2	717:759	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	9	25	from	use	1093:1095	arg1	construction					1109:1120	building construction	1100:1120	building construction	1100:1120	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	4	26	theme	MPa	485:487	arg1	pressure					469:476	a pressure	467:476	a pressure of 2.6 MPa for 1, 2, and 3 h	467:505	The mix was pressed at a temperature of 110 °C with a pressure of 2.6 MPa for 1, 2, and 3 h.					
36364130	1	27	with	reed	191:194	arg1	starch					220:225	starch	220:225	starch	220:225	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	1	27	with	reed	191:194	arg1	plaster					208:214	gypsum plaster	201:214	gypsum plaster	201:214	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	1	28	theme	gypsum	201:206	arg1	plaster					208:214	gypsum plaster	201:214	gypsum plaster	201:214	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36364130	0	29	theme	Particleboards	43:56	arg1	Properties					18:27	the Properties	14:27	the Properties of Giant Reed Particleboards	14:56	Assessment of the Properties of Giant Reed Particleboards Agglomerated with Gypsum Plaster and Starch.					
36364130	9	30	theme	mechanical	1031:1040	arg1	properties					1042:1051	physical and mechanical properties	1018:1051	physical and mechanical properties that comply with European standards for use in building construction	1018:1120	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	2	31	theme	particles	331:339	arg1	amounts					355:361	different amounts	345:361	different amounts of starch	345:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	31	theme	particles	331:339	arg1	starch					366:371	starch	366:371	starch	366:371	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	31	theme	particles	331:339	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	2	31	theme	particles	331:339	arg1	ratio					296:300	a 10:2 weight ratio	282:300	a 10:2 weight ratio of giant reed/gypsum plaster particles	282:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	0	32	theme	Reed	38:41	arg1	Particleboards					43:56	Giant Reed Particleboards	32:56	Giant Reed Particleboards	32:56	Assessment of the Properties of Giant Reed Particleboards Agglomerated with Gypsum Plaster and Starch.					
36364130	6	33	theme	bounding	778:785	arg1	strength					787:794	an internal bounding strength	766:794	an internal bounding strength (IB) of 0.62 N/mm2	766:813	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	33	theme	bounding	778:785	arg1	IB					797:798	IB	797:798	IB	797:798	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	2	34	theme	plaster	323:329	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	6	35	theme	internal	769:776	arg1	strength					787:794	an internal bounding strength	766:794	an internal bounding strength (IB) of 0.62 N/mm2	766:813	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	35	theme	internal	769:776	arg1	IB					797:798	IB	797:798	IB	797:798	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	36	theme	mechanical	642:651	arg1	properties					653:662	the best physical and mechanical properties	620:662	the best physical and mechanical properties	620:662	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	2	37	theme	reed/gypsum	311:321	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	6	38	theme	N/mm2	710:714	arg1	MOR					697:699	MOR	697:699	MOR	697:699	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	6	38	theme	N/mm2	710:714	arg1	rupture					688:694	rupture	688:694	rupture (MOR) of 17.5 N/mm2	688:714	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	2	39	theme	Experimental	239:250	arg1	boards					252:257	Experimental boards	239:257	Experimental boards	239:257	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	7	40	theme	Thickness	816:824	arg1	TS					836:837	TS	836:837	TS	836:837	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	7	40	theme	Thickness	816:824	arg1	swelling					826:833	Thickness swelling	816:833	Thickness swelling (TS) at 24 h of the panels	816:860	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	2	41	theme	giant	305:309	arg1	particles					331:339	giant reed/gypsum plaster particles	305:339	giant reed/gypsum plaster particles	305:339	Experimental boards were manufactured with a 10:2 weight ratio of giant reed/gypsum plaster particles and different amounts of starch.					
36364130	7	42	theme	%	884:884	arg1	%					894:894	36.16% to 28.37%	879:894	36.16% to 28.37% when 10 wt	879:905	Thickness swelling (TS) at 24 h of the panels was reduced from 36.16% to 28.37% when 10 wt.					
36364130	8	43	theme	%	907:907	arg1	starch					909:914	% starch	907:914	% starch	907:914	% starch was added.					
36364130	6	44	theme	physical	629:636	arg1	properties					653:662	the best physical and mechanical properties	620:662	the best physical and mechanical properties	620:662	% starch achieved the best physical and mechanical properties, obtaining a modulus of rupture (MOR) of 17.5 N/mm2, a modulus of elasticity (MOE) of 3196 N/mm2, and an internal bounding strength (IB) of 0.62 N/mm2.					
36364130	5	45	dep	showed	520:525	arg1	boards					536:541	the boards	532:541	the boards manufactured with longer times in the press and with 10 wt	532:600	The results showed that the boards manufactured with longer times in the press and with 10 wt.					
36364130	9	46	theme	European	1070:1077	arg1	standards					1079:1087	European standards	1070:1087	European standards	1070:1087	These results showed that giant reed-gypsum-starch particleboards can be manufactured with physical and mechanical properties that comply with European standards for use in building construction.					
36364130	1	47	theme	composite	141:149	arg1	particleboards					151:164	composite particleboards	141:164	composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders	141:236	This paper analyzes the properties of composite particleboards made from a mix of giant reed with gypsum plaster and starch as binders.					
36241307	6	0	theme	composite	915:923	arg1	hydrogels					925:933	the composite hydrogels	911:933	the composite hydrogels	911:933	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	2	1	theme	hydrogels	406:414	arg1	properties					377:386	the mechanical properties	362:386	the mechanical properties of polyacrylamide hydrogels	362:414	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	4	2	theme	CMNPs	645:649	arg1	behavior					629:636	the aggregation behavior	613:636	the aggregation behavior of the CMNPs	613:649	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	0	3	theme	chitosan	90:97	arg1	assembly					78:85	a confined assembly	67:85	a confined assembly of chitosan and γ-cyclodextrin	67:116	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	0	4	link	cross-linked	40:51	arg1	hydrogels					53:61	cross-linked hydrogels	40:61	cross-linked hydrogels	40:61	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	2	5	theme	polyacrylamide	391:404	arg1	hydrogels					406:414	polyacrylamide hydrogels	391:414	polyacrylamide hydrogels	391:414	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	7	6	theme	electronics	1180:1190	arg1	field					1153:1157	the field	1149:1157	the field of wearable flexible electronics	1149:1190	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	6	7	dep	strain	1008:1013	arg1	%					1022:1022	~1000 %	1016:1022	~1000 %	1016:1022	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	8	theme	fracture	999:1006	arg1	strain					1008:1013	fracture strain	999:1013	fracture strain	999:1013	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	8	theme	fracture	999:1006	arg1	properties					987:996	the tensile properties	975:996	the tensile properties (fracture strain, ~1000 %)	975:1023	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	0	9	theme	γ-cyclodextrin	103:116	arg1	assembly					78:85	a confined assembly	67:85	a confined assembly of chitosan and γ-cyclodextrin	67:116	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	2	10	theme	micro-nanoparticles	323:341	arg1	modulation					297:306	ionic interaction modulation	279:306	ionic interaction modulation of crystalline micro-nanoparticles (CMNPs)	279:349	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	7	11	theme	wearable	1162:1169	arg1	electronics					1180:1190	wearable flexible electronics	1162:1190	wearable flexible electronics	1162:1190	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	2	12	theme	crystalline	311:321	arg1	micro-nanoparticles					323:341	crystalline micro-nanoparticles	311:341	crystalline micro-nanoparticles (CMNPs)	311:349	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	2	12	theme	crystalline	311:321	arg1	CMNPs					344:348	CMNPs	344:348	CMNPs	344:348	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	7	13	theme	flexible	1171:1178	arg1	electronics					1180:1190	wearable flexible electronics	1162:1190	wearable flexible electronics	1162:1190	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	1	14	contain	have	181:184	arg2	properties					202:211	poor mechanical properties	186:211	poor mechanical properties limiting their applications	186:239	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
36241307	1	14	contain	have	181:184	arg1	Hydrogels					119:127	Hydrogels	119:127	Hydrogels constructed by traditional polymer networks	119:171	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
36241307	7	15	theme	human	1090:1094	arg1	motion					1096:1101	human motion	1090:1101	human motion	1090:1101	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	6	16	theme	fracture	825:832	arg1	stress					834:839	fracture stress	825:839	fracture stress (1054.59 kPa, 25.3 times)	825:865	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	3	17	theme	confinement	439:449	arg1	assembly					451:458	confinement assembly	439:458	confinement assembly	439:458	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	3	18	theme	host-guest	495:504	arg1	interactions					506:517	host-guest interactions	495:517	host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD)	495:597	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	0	19	theme	Crystalline	0:10	arg1	micro-nanoparticles					12:30	Crystalline micro-nanoparticles	0:30	Crystalline micro-nanoparticles	0:30	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	4	20	theme	aggregation	617:627	arg1	behavior					629:636	the aggregation behavior	613:636	the aggregation behavior of the CMNPs	613:649	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	0	21	theme	cross-linked	40:51	arg1	hydrogels					53:61	cross-linked hydrogels	40:61	cross-linked hydrogels	40:61	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	6	22	theme	tensile	979:985	arg1	strain					1008:1013	fracture strain	999:1013	fracture strain	999:1013	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	22	theme	tensile	979:985	arg1	properties					987:996	the tensile properties	975:996	the tensile properties (fracture strain, ~1000 %)	975:1023	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	7	23	theme	strain	1057:1062	arg1	sensor					1064:1069	a strain sensor	1055:1069	a strain sensor that could monitor human motion	1055:1101	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	6	24	dep	stress	834:839	arg1	1054.59 kPa					842:852	1054.59 kPa	842:852	1054.59 kPa	842:852	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	24	dep	stress	834:839	arg1	times					860:864	25.3 times	855:864	25.3 times	855:864	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	3	25	theme	chitosan-grafted	527:542	arg1	CS-PEG					565:570	CS-PEG	565:570	CS-PEG	565:570	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	3	25	theme	chitosan-grafted	527:542	arg1	glycol					557:562	chitosan-grafted polyethylene glycol	527:562	chitosan-grafted polyethylene glycol (CS-PEG)	527:571	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	1	26	theme	mechanical	191:200	arg1	properties					202:211	poor mechanical properties	186:211	poor mechanical properties limiting their applications	186:239	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
36241307	3	27	theme	polyethylene	544:555	arg1	CS-PEG					565:570	CS-PEG	565:570	CS-PEG	565:570	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	3	27	theme	polyethylene	544:555	arg1	glycol					557:562	chitosan-grafted polyethylene glycol	527:562	chitosan-grafted polyethylene glycol (CS-PEG)	527:571	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	7	28	theme	potential	1124:1132	arg1	application					1134:1144	its potential application	1120:1144	its potential application in the field of wearable flexible electronics	1120:1190	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	3	29	theme	aggregated	469:478	arg1	state					480:484	an aggregated state	466:484	an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD)	466:597	CMNPs were formed via confinement assembly under an aggregated state based on host-guest interactions between chitosan-grafted polyethylene glycol (CS-PEG) and γ-cyclodextrin (γ-CD).					
36241307	6	30	dep	toughness	872:880	arg1	times					901:905	41.7 times	896:905	41.7 times	896:905	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	30	dep	toughness	872:880	arg1	6.23 MJ m-3					883:893	6.23 MJ m-3	883:893	6.23 MJ m-3	883:893	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	5	31	theme	PAM	772:774	arg1	hydrogels					776:784	PAM hydrogels	772:784	PAM hydrogels	772:784	These Cit3--regulated CMNPs were introduced into PAM hydrogels.					
36241307	2	32	theme	new	262:264	arg1	strategy					266:273	a new strategy	260:273	a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs)	260:349	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	4	33	theme	CS	698:699	arg1	interaction					683:693	the ionic interaction	673:693	the ionic interaction of CS with citrate (Cit3-)	673:720	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	0	34	theme	confined	69:76	arg1	assembly					78:85	a confined assembly	67:85	a confined assembly of chitosan and γ-cyclodextrin	67:116	Crystalline micro-nanoparticles enhance cross-linked hydrogels via a confined assembly of chitosan and γ-cyclodextrin.					
36241307	7	35	from	application	1134:1144	arg1	field					1153:1157	the field	1149:1157	the field of wearable flexible electronics	1149:1190	Finally, we further designed a strain sensor that could monitor human motion, and we verified its potential application in the field of wearable flexible electronics.					
36241307	6	36	theme	hydrogels	925:933	arg1	toughness					872:880	toughness	872:880	toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels	872:933	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	36	theme	hydrogels	925:933	arg1	modulus					791:797	The modulus	787:797	The modulus (618.44 kPa, 67.6 times)	787:822	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	36	theme	hydrogels	925:933	arg1	stress					834:839	fracture stress	825:839	fracture stress (1054.59 kPa, 25.3 times)	825:865	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	1	37	theme	traditional	144:154	arg1	networks					164:171	traditional polymer networks	144:171	traditional polymer networks	144:171	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
36241307	5	38	theme	Cit3--regulated	729:743	arg1	CMNPs					745:749	These Cit3--regulated CMNPs	723:749	These Cit3--regulated CMNPs	723:749	These Cit3--regulated CMNPs were introduced into PAM hydrogels.					
36241307	1	39	theme	polymer	156:162	arg1	networks					164:171	traditional polymer networks	144:171	traditional polymer networks	144:171	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
36241307	2	40	theme	interaction	285:295	arg1	modulation					297:306	ionic interaction modulation	279:306	ionic interaction modulation of crystalline micro-nanoparticles (CMNPs)	279:349	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	6	41	dep	modulus	791:797	arg1	618.44 kPa					800:809	618.44 kPa	800:809	618.44 kPa	800:809	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	6	41	dep	modulus	791:797	arg1	times					817:821	67.6 times	812:821	67.6 times	812:821	The modulus (618.44 kPa, 67.6 times), fracture stress (1054.59 kPa, 25.3 times), and toughness (6.23 MJ m-3, 41.7 times) of the composite hydrogels were greatly improved without affecting the tensile properties (fracture strain, ~1000 %).					
36241307	2	42	theme	mechanical	366:375	arg1	properties					377:386	the mechanical properties	362:386	the mechanical properties of polyacrylamide hydrogels	362:414	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	4	43	with	interaction	683:693	arg1	Cit3-					715:719	Cit3-	715:719	Cit3-	715:719	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	4	43	with	interaction	683:693	arg1	citrate					706:712	citrate	706:712	citrate (Cit3-)	706:720	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	2	44	theme	ionic	279:283	arg1	modulation					297:306	ionic interaction modulation	279:306	ionic interaction modulation of crystalline micro-nanoparticles (CMNPs)	279:349	Here, we proposed a new strategy for ionic interaction modulation of crystalline micro-nanoparticles (CMNPs) to enhance the mechanical properties of polyacrylamide hydrogels.					
36241307	4	45	theme	ionic	677:681	arg1	interaction					683:693	the ionic interaction	673:693	the ionic interaction of CS with citrate (Cit3-)	673:720	Furthermore, the aggregation behavior of the CMNPs was achieved based on the ionic interaction of CS with citrate (Cit3-).					
36241307	1	46	theme	poor	186:189	arg1	properties					202:211	poor mechanical properties	186:211	poor mechanical properties limiting their applications	186:239	Hydrogels constructed by traditional polymer networks usually have poor mechanical properties limiting their applications.					
37258214	3	0	theme	excellent	314:322	arg1	abilities					346:354	excellent Pickering emulsifying abilities	314:354	excellent Pickering emulsifying abilities	314:354	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	5	1	theme	high	650:653	arg1	performance					670:680	high emulsification performance	650:680	high emulsification performance	650:680	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	5	2	theme	small	550:554	arg1	lignin					566:571	lignin	566:571	lignin	566:571	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	5	2	theme	small	550:554	arg1	amount					556:561	a small amount	548:561	a small amount of lignin without pectin	548:586	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	3	3	theme	Pickering	324:332	arg1	abilities					346:354	excellent Pickering emulsifying abilities	314:354	excellent Pickering emulsifying abilities	314:354	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	5	4	theme	emulsification	655:668	arg1	performance					670:680	high emulsification performance	650:680	high emulsification performance	650:680	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	6	5	contain	had	710:712	arg2	compositions					730:741	different fiber compositions	714:741	different fiber compositions	714:741	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	6	5	contain	had	710:712	arg1	powders					702:708	these two powders	692:708	these two powders	692:708	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	3	6	theme	water-soluble	365:377	arg1	components					379:388	the water-soluble components	361:388	the water-soluble components	361:388	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	5	7	theme	further	611:617	arg1	treatment					627:635	further solvent treatment	611:635	further solvent treatment	611:635	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	1	8	theme	Quince	75:80	arg1	powder					88:93	Quince fruit powder	75:93	Quince fruit powder	75:93	Quince fruit powder can be obtained from the waste of the edible product.					
37258214	5	9	theme	solvent	619:625	arg1	treatment					627:635	further solvent treatment	611:635	further solvent treatment	611:635	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	1	10	theme	fruit	82:86	arg1	powder					88:93	Quince fruit powder	75:93	Quince fruit powder	75:93	Quince fruit powder can be obtained from the waste of the edible product.					
37258214	6	11	theme	fiber	724:728	arg1	compositions					730:741	different fiber compositions	714:741	different fiber compositions	714:741	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	4	12	contain	contains	441:448	arg2	fibers					492:497	hydrophobic lignin fibers	473:497	hydrophobic lignin fibers	473:497	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	4	12	contain	contains	441:448	arg1	powder					434:439	the powder	430:439	the powder	430:439	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	4	12	contain	contains	441:448	arg2	pectin					462:467	hydrophilic pectin	450:467	hydrophilic pectin	450:467	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	6	13	theme	surface	800:806	arg1	hydrophilicity					808:821	their surface hydrophilicity	794:821	their surface hydrophilicity	794:821	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	3	14	contain	possessed	304:312	arg2	abilities					346:354	excellent Pickering emulsifying abilities	314:354	excellent Pickering emulsifying abilities	314:354	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	3	14	contain	possessed	304:312	arg1	fruit					298:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	0	15	theme	Pickering	16:24	arg1	Emulsification					26:39	Surfactant-Free Pickering Emulsification	0:39	Surfactant-Free Pickering Emulsification	0:39	Surfactant-Free Pickering Emulsification Using Chinese Quince Fruit Fiber.					
37258214	0	16	theme	Surfactant-Free	0:14	arg1	Emulsification					26:39	Surfactant-Free Pickering Emulsification	0:39	Surfactant-Free Pickering Emulsification	0:39	Surfactant-Free Pickering Emulsification Using Chinese Quince Fruit Fiber.					
37258214	3	17	theme	crushed	275:281	arg1	fruit					298:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	0	18	theme	Quince	55:60	arg1	Fiber					68:72	Chinese Quince Fruit Fiber	47:72	Chinese Quince Fruit Fiber	47:72	Surfactant-Free Pickering Emulsification Using Chinese Quince Fruit Fiber.					
37258214	6	19	theme	emulsification	880:893	arg1	ability					895:901	emulsification ability	880:901	emulsification ability	880:901	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	0	20	theme	Chinese	47:53	arg1	Fiber					68:72	Chinese Quince Fruit Fiber	47:72	Chinese Quince Fruit Fiber	47:72	Surfactant-Free Pickering Emulsification Using Chinese Quince Fruit Fiber.					
37258214	4	21	theme	lignin	485:490	arg1	fibers					492:497	hydrophobic lignin fibers	473:497	hydrophobic lignin fibers	473:497	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	4	22	theme	hydrophobic	473:483	arg1	fibers					492:497	hydrophobic lignin fibers	473:497	hydrophobic lignin fibers	473:497	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	0	23	theme	Fruit	62:66	arg1	Fiber					68:72	Chinese Quince Fruit Fiber	47:72	Chinese Quince Fruit Fiber	47:72	Surfactant-Free Pickering Emulsification Using Chinese Quince Fruit Fiber.					
37258214	6	24	theme	cellulose-only	850:863	arg1	powder					865:870	the cellulose-only powder	846:870	the cellulose-only powder without emulsification ability	846:901	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	2	25	theme	various	192:198	arg1	solvents					200:207	various solvents	192:207	various solvents	192:207	In this study, we modified the powder with various solvents and investigated its application in Pickering emulsification.					
37258214	5	26	theme	lignin	566:571	arg1	powder					513:518	a powder	511:518	a powder consisting of cellulose	511:542	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	5	26	theme	lignin	566:571	arg1	lignin					566:571	lignin	566:571	lignin	566:571	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	5	26	theme	lignin	566:571	arg1	amount					556:561	a small amount	548:561	a small amount of lignin without pectin	548:586	Similarly, a powder consisting of cellulose and a small amount of lignin without pectin, which was obtained by further solvent treatment, also showed high emulsification performance.					
37258214	3	27	theme	Chinese	283:289	arg1	fruit					298:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	2	28	theme	Pickering	245:253	arg1	emulsification					255:268	Pickering emulsification	245:268	Pickering emulsification	245:268	In this study, we modified the powder with various solvents and investigated its application in Pickering emulsification.					
37258214	3	29	theme	quince	291:296	arg1	fruit					298:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit	271:302	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	4	30	theme	hydrophilic	450:460	arg1	pectin					462:467	hydrophilic pectin	450:467	hydrophilic pectin	450:467	In addition to cellulose, the powder contains hydrophilic pectin and hydrophobic lignin fibers.					
37258214	6	31	theme	contact	756:762	arg1	angles					764:769	their water contact angles	744:769	their water contact angles	744:769	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	6	32	theme	different	714:722	arg1	compositions					730:741	different fiber compositions	714:741	different fiber compositions	714:741	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	3	33	theme	emulsifying	334:344	arg1	abilities					346:354	excellent Pickering emulsifying abilities	314:354	excellent Pickering emulsifying abilities	314:354	The crushed Chinese quince fruit possessed excellent Pickering emulsifying abilities when the water-soluble components were removed.					
37258214	6	34	theme	water	750:754	arg1	angles					764:769	their water contact angles	744:769	their water contact angles	744:769	Although these two powders had different fiber compositions, their water contact angles were almost equal, and their surface hydrophilicity was lower than that of the cellulose-only powder without emulsification ability.					
37258214	1	35	theme	edible	133:138	arg1	product					140:146	the edible product	129:146	the edible product	129:146	Quince fruit powder can be obtained from the waste of the edible product.					
37258214	1	36	theme	product	140:146	arg1	waste					120:124	the waste	116:124	the waste of the edible product	116:146	Quince fruit powder can be obtained from the waste of the edible product.					
36705863	0	0	theme	chitosan-pectin	71:85	arg1	bio-adsorbent					87:99	an efficient chitosan-pectin bio-adsorbent	58:99	an efficient chitosan-pectin bio-adsorbent	58:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	13	1	theme	adsorbing	1861:1869	arg1	capability					1871:1880	its strong adsorbing capability	1850:1880	its strong adsorbing capability	1850:1880	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	12	2	theme	MB	1731:1732	arg1	removal					1720:1726	the removal	1716:1726	the removal of MB onto the adsorbent	1716:1751	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	0	3	dep	studies	124:130	arg1	Removal					0:6	Removal	0:6	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent	0:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	12	4	theme	Electrostatic	1651:1663	arg1	mechanisms					1701:1710	the main mechanisms	1692:1710	the main mechanisms for the removal of MB onto the adsorbent	1692:1751	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	12	4	theme	Electrostatic	1651:1663	arg1	interactions					1675:1686	Electrostatic and pi-pi interactions	1651:1686	interactions	1675:1686	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	6	5	theme	L-1	894:896	arg1	concentration					871:883	an initial MB concentration	857:883	an initial MB concentration of 50 mg L-1	857:896	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	0	6	theme	efficient	61:69	arg1	bio-adsorbent					87:99	an efficient chitosan-pectin bio-adsorbent	58:99	an efficient chitosan-pectin bio-adsorbent	58:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	8	7	contain	had	1102:1104	arg1	Cs-Pc					1096:1100	Cs-Pc	1096:1100	Cs-Pc	1096:1100	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	8	7	contain	had	1102:1104	arg2	ability					1115:1121	a higher ability	1106:1121	a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption	1106:1279	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	7	8	theme	sorbate	1076:1082	arg1	dose					1084:1087	sorbate dose	1076:1087	sorbate dose	1076:1087	In addition, the removal efficiency of MB was more influenced by pH than by sorbate dose.					
36705863	9	9	theme	removal	1294:1300	arg1	efficiency					1302:1311	maximum removal efficiency	1286:1311	maximum removal efficiency	1286:1311	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	4	10	theme	solution	538:545	arg1	pH					547:548	solution pH	538:548	solution pH	538:548	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	5	11	theme	dispersive	660:669	arg1	spectroscopy					677:688	energy dispersive X-ray spectroscopy	653:688	energy dispersive X-ray spectroscopy (EDX)	653:694	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	11	theme	dispersive	660:669	arg1	FTIR					725:728	FTIR	725:728	FTIR	725:728	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	11	theme	dispersive	660:669	arg1	EDX					691:693	EDX	691:693	EDX	691:693	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	11	theme	dispersive	660:669	arg1	Fourier					697:703	Fourier	697:703	Fourier transform infrared	697:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	13	12	theme	excellent	1902:1910	arg1	ability					1912:1918	its excellent ability	1898:1918	its excellent ability to reuse	1898:1927	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	10	13	theme	Freundlich	1541:1550	arg1	equation					1552:1559	pseudo-second-order and Freundlich equation	1517:1559	pseudo-second-order and Freundlich equation	1517:1559	The adsorption kinetics and isotherms were best described by pseudo-second-order and Freundlich equation, respectively.					
36705863	6	14	dep	dose	923:926	arg1	time					959:962	180 min contact time	943:962	180 min contact time	943:962	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	6	14	dep	dose	923:926	arg1	L-1					935:937	1.5 g L-1	929:937	1.5 g L-1	929:937	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	9	15	theme	optimum	1392:1398	arg1	conditions					1400:1409	optimum conditions	1392:1409	optimum conditions	1392:1409	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	4	16	theme	contact	551:557	arg1	time					559:562	contact time	551:562	contact time	551:562	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	5	17	theme	X-ray	671:675	arg1	spectroscopy					677:688	energy dispersive X-ray spectroscopy	653:688	energy dispersive X-ray spectroscopy (EDX)	653:694	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	17	theme	X-ray	671:675	arg1	FTIR					725:728	FTIR	725:728	FTIR	725:728	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	17	theme	X-ray	671:675	arg1	EDX					691:693	EDX	691:693	EDX	691:693	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	17	theme	X-ray	671:675	arg1	Fourier					697:703	Fourier	697:703	Fourier transform infrared	697:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	0	18	from	solution	43:50	arg1	Removal					0:6	Removal	0:6	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent	0:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	13	19	theme	Cs-Pc	1776:1780	arg1	promising					1785:1793	promising	1785:1793	promising	1785:1793	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	13	19	theme	Cs-Pc	1776:1780	arg1	application					1761:1771	So the application	1754:1771	So the application of Cs-Pc	1754:1780	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	11	20	theme	recycling	1596:1604	arg1	times					1587:1591	four times	1582:1591	four times of recycling	1582:1604	After four times of recycling, the removal efficiency of MB was above 96%.					
36705863	8	21	theme	higher	1108:1113	arg1	ability					1115:1121	a higher ability	1106:1121	a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption	1106:1279	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	6	22	theme	contact	951:957	arg1	time					959:962	180 min contact time	943:962	180 min contact time	943:962	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	8	23	theme	MB	1267:1268	arg1	adsorption					1270:1279	MB adsorption	1267:1279	MB adsorption	1267:1279	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	10	24	theme	adsorption	1460:1469	arg1	kinetics					1471:1478	The adsorption kinetics	1456:1478	The adsorption kinetics	1456:1478	The adsorption kinetics and isotherms were best described by pseudo-second-order and Freundlich equation, respectively.					
36705863	3	25	theme	blue	408:411	arg1	MB					418:419	MB	418:419	MB	418:419	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	3	25	theme	blue	408:411	arg1	dye					413:415	methylene blue dye	398:415	methylene blue dye (MB)	398:420	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	0	26	theme	kinetics	102:109	arg1	studies					124:130	kinetics and isotherm studies	102:130	kinetics and isotherm studies	102:130	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	9	27	theme	500 mg	1361:1366	arg1	concentration					1372:1384	500 mg L-1 concentration	1361:1384	500 mg L-1 concentration under optimum conditions	1361:1409	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	6	28	theme	180 min	943:949	arg1	time					959:962	180 min contact time	943:962	180 min contact time	943:962	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	7	29	theme	removal	1017:1023	arg1	efficiency					1025:1034	the removal efficiency	1013:1034	the removal efficiency of MB	1013:1040	In addition, the removal efficiency of MB was more influenced by pH than by sorbate dose.					
36705863	1	30	contain	contains	144:151	arg2	compounds					161:169	organic compounds	153:169	organic compounds	153:169	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	1	30	contain	contains	144:151	arg1	Wastewater					133:142	Wastewater	133:142	Wastewater	133:142	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	1	30	contain	contains	144:151	arg2	dyes					182:185	dyes	182:185	dyes	182:185	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	5	31	dep	transform	705:713	arg1	infrared					715:722	infrared	715:722	transform infrared	705:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	6	32	theme	MB	868:869	arg1	concentration					871:883	an initial MB concentration	857:883	an initial MB concentration of 50 mg L-1	857:896	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	5	33	dep	Fourier	697:703	arg1	transform					705:713	transform	705:713	transform infrared	705:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	34	theme	electron	626:633	arg1	microscopy					635:644	Scanning electron microscopy	617:644	Scanning electron microscopy (SEM)	617:650	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	34	theme	electron	626:633	arg1	SEM					647:649	SEM	647:649	SEM	647:649	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	12	35	theme	main	1696:1699	arg1	mechanisms					1701:1710	the main mechanisms	1692:1710	the main mechanisms for the removal of MB onto the adsorbent	1692:1751	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	12	35	theme	main	1696:1699	arg1	interactions					1675:1686	Electrostatic and pi-pi interactions	1651:1686	interactions	1675:1686	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	4	36	theme	MB	520:521	arg1	concentration					523:535	the initial MB concentration	508:535	the initial MB concentration	508:535	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	0	37	theme	blue	21:24	arg1	dye					26:28	methylene blue dye	11:28	methylene blue dye	11:28	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	4	38	theme	initial	512:518	arg1	concentration					523:535	the initial MB concentration	508:535	the initial MB concentration	508:535	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	2	39	theme	aqueous	289:295	arg1	solution					297:304	the aqueous solution	285:304	the aqueous solution	285:304	Hence, these compound needs to be eliminated from the aqueous solution.					
36705863	6	40	theme	1.5 g	929:933	arg1	L-1					935:937	1.5 g L-1	929:937	1.5 g L-1	929:937	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	0	41	theme	methylene	11:19	arg1	dye					26:28	methylene blue dye	11:28	methylene blue dye	11:28	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	11	42	theme	removal	1611:1617	arg1	efficiency					1619:1628	the removal efficiency	1607:1628	the removal efficiency of MB	1607:1634	After four times of recycling, the removal efficiency of MB was above 96%.					
36705863	0	43	theme	isotherm	115:122	arg1	studies					124:130	kinetics and isotherm studies	102:130	kinetics and isotherm studies	102:130	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	10	44	theme	pseudo-second-order	1517:1535	arg1	equation					1552:1559	pseudo-second-order and Freundlich equation	1517:1559	pseudo-second-order and Freundlich equation	1517:1559	The adsorption kinetics and isotherms were best described by pseudo-second-order and Freundlich equation, respectively.					
36705863	6	45	theme	removal	991:997	arg1	%					983:983	97.77%	978:983	97.77% of MB removal	978:997	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	6	45	theme	removal	991:997	arg1	removal					991:997	MB removal	988:997	MB removal	988:997	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	9	46	theme	MB	1344:1345	arg1	capacity					1332:1339	the adsorption capacity	1317:1339	the adsorption capacity of MB	1317:1345	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	9	46	theme	MB	1344:1345	arg1	%					1421:1421	98.67%	1416:1421	98.67%	1416:1421	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	9	46	theme	MB	1344:1345	arg1	efficiency					1302:1311	maximum removal efficiency	1286:1311	maximum removal efficiency	1286:1311	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	1	47	theme	potential	199:207	arg1	risks					209:213	potential risks	199:213	potential risks	199:213	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	9	48	theme	L-1	1368:1370	arg1	concentration					1372:1384	500 mg L-1 concentration	1361:1384	500 mg L-1 concentration under optimum conditions	1361:1409	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	3	49	used	used	367:370	arg2	Cs-Pc					356:360	Cs-Pc	356:360	Cs-Pc	356:360	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	3	49	used	used	367:370	arg2	composite					345:353	chitosan-pectin composite	329:353	chitosan-pectin composite (Cs-Pc)	329:361	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	3	49	used	used	367:370	arg2	adsorbent					378:386	adsorbent	378:386	adsorbent	378:386	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	7	50	theme	MB	1039:1040	arg1	efficiency					1025:1034	the removal efficiency	1013:1034	the removal efficiency of MB	1013:1040	In addition, the removal efficiency of MB was more influenced by pH than by sorbate dose.					
36705863	9	51	from	concentration	1372:1384	arg1	capacity					1332:1339	the adsorption capacity	1317:1339	the adsorption capacity of MB	1317:1345	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	9	51	from	concentration	1372:1384	arg1	%					1421:1421	98.67%	1416:1421	98.67%	1416:1421	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	9	51	from	concentration	1372:1384	arg1	efficiency					1302:1311	maximum removal efficiency	1286:1311	maximum removal efficiency	1286:1311	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	0	52	theme	dye	26:28	arg1	Removal					0:6	Removal	0:6	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent	0:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	5	53	theme	energy	653:658	arg1	spectroscopy					677:688	energy dispersive X-ray spectroscopy	653:688	energy dispersive X-ray spectroscopy (EDX)	653:694	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	53	theme	energy	653:658	arg1	FTIR					725:728	FTIR	725:728	FTIR	725:728	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	53	theme	energy	653:658	arg1	EDX					691:693	EDX	691:693	EDX	691:693	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	53	theme	energy	653:658	arg1	Fourier					697:703	Fourier	697:703	Fourier transform infrared	697:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	6	54	theme	50 mg	888:892	arg1	L-1					894:896	50 mg L-1	888:896	50 mg L-1	888:896	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	6	55	theme	solution	899:906	arg1	pH ~ 11					908:914	solution pH ~ 11	899:914	solution pH ~ 11	899:914	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	6	55	theme	solution	899:906	arg1	dose					923:926	Cs-Pc dose	917:926	Cs-Pc dose: 1.5 g L-1 and 180 min contact time	917:962	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	5	56	theme	charges	753:759	arg1	point					739:743	pH point	736:743	pH point of zero charges (pH pzc)	736:768	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	FTIR					725:728	FTIR	725:728	FTIR	725:728	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	EDX					691:693	EDX	691:693	EDX	691:693	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	Fourier					697:703	Fourier	697:703	Fourier transform infrared	697:722	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	microscopy					635:644	Scanning electron microscopy	617:644	Scanning electron microscopy (SEM)	617:650	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	spectroscopy					677:688	energy dispersive X-ray spectroscopy	653:688	energy dispersive X-ray spectroscopy (EDX)	653:694	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	56	theme	charges	753:759	arg1	SEM					647:649	SEM	647:649	SEM	647:649	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	4	57	theme	batch	581:585	arg1	experiments					587:597	batch experiments	581:597	batch experiments	581:597	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	5	58	theme	Scanning	617:624	arg1	microscopy					635:644	Scanning electron microscopy	617:644	Scanning electron microscopy (SEM)	617:650	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	5	58	theme	Scanning	617:624	arg1	SEM					647:649	SEM	647:649	SEM	647:649	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	6	59	theme	initial	860:866	arg1	concentration					871:883	an initial MB concentration	857:883	an initial MB concentration of 50 mg L-1	857:896	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	8	60	theme	rough	1210:1214	arg1	surfaces					1216:1223	MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces	1133:1223	MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites	1133:1250	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	13	61	theme	polluted	1815:1822	arg1	solutions					1824:1832	polluted solutions	1815:1832	polluted solutions	1815:1832	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	6	62	theme	MB	988:989	arg1	removal					991:997	MB removal	988:997	MB removal	988:997	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	0	63	theme	aqueous	35:41	arg1	solution					43:50	aqueous solution	35:50	aqueous solution using an efficient chitosan-pectin bio-adsorbent	35:99	Removal of methylene blue dye from aqueous solution using an efficient chitosan-pectin bio-adsorbent: kinetics and isotherm studies.					
36705863	3	64	theme	chitosan-pectin	329:343	arg1	adsorbent					378:386	adsorbent	378:386	adsorbent	378:386	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	3	64	theme	chitosan-pectin	329:343	arg1	Cs-Pc					356:360	Cs-Pc	356:360	Cs-Pc	356:360	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	3	64	theme	chitosan-pectin	329:343	arg1	composite					345:353	chitosan-pectin composite	329:353	chitosan-pectin composite (Cs-Pc)	329:361	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	6	65	theme	Cs-Pc	917:921	arg1	pH ~ 11					908:914	solution pH ~ 11	899:914	solution pH ~ 11	899:914	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	6	65	theme	Cs-Pc	917:921	arg1	dose					923:926	Cs-Pc dose	917:926	Cs-Pc dose: 1.5 g L-1 and 180 min contact time	917:962	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	5	66	theme	Cs-Pc	808:812	arg1	characterizations					787:803	characterizations	787:803	characterizations of Cs-Pc	787:812	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	6	67	theme	optimum	819:825	arg1	conditions					827:836	The optimum conditions	815:836	The optimum conditions	815:836	The optimum conditions were obtained with an initial MB concentration of 50 mg L-1: solution pH ~ 11, Cs-Pc dose: 1.5 g L-1 and 180 min contact time, which caused 97.77% of MB removal.					
36705863	12	68	theme	pi-pi	1669:1673	arg1	mechanisms					1701:1710	the main mechanisms	1692:1710	the main mechanisms for the removal of MB onto the adsorbent	1692:1751	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	12	68	theme	pi-pi	1669:1673	arg1	interactions					1675:1686	Electrostatic and pi-pi interactions	1651:1686	interactions	1675:1686	Electrostatic and pi-pi interactions are the main mechanisms for the removal of MB onto the adsorbent.					
36705863	8	69	theme	porous	1189:1194	arg1	structure					1196:1204	its highly porous structure	1178:1204	its highly porous structure	1178:1204	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	3	70	theme	synthetic	427:435	arg1	wastewater					437:446	synthetic wastewater	427:446	synthetic wastewater	427:446	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	9	71	dep	efficiency	1302:1311	arg1	The					1282:1284	The	1282:1284	The	1282:1284	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	11	72	theme	MB	1633:1634	arg1	efficiency					1619:1628	the removal efficiency	1607:1628	the removal efficiency of MB	1607:1634	After four times of recycling, the removal efficiency of MB was above 96%.					
36705863	3	73	theme	present	314:320	arg1	study					322:326	the present study	310:326	the present study	310:326	In the present study, chitosan-pectin composite (Cs-Pc) was used as an adsorbent to remove methylene blue dye (MB) from synthetic wastewater.					
36705863	1	74	contain	have	194:197	arg2	risks					209:213	potential risks	199:213	potential risks	199:213	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	1	74	contain	have	194:197	arg1	compounds					161:169	organic compounds	153:169	organic compounds	153:169	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	1	74	contain	have	194:197	arg1	dyes					182:185	dyes	182:185	dyes	182:185	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	8	75	theme	active	1239:1244	arg1	sites					1246:1250	active sites	1239:1250	active sites	1239:1250	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	9	76	theme	adsorption	1321:1330	arg1	capacity					1332:1339	the adsorption capacity	1317:1339	the adsorption capacity of MB	1317:1345	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	9	76	theme	adsorption	1321:1330	arg1	%					1421:1421	98.67%	1416:1421	98.67%	1416:1421	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	8	77	theme	MB	1133:1134	arg1	surfaces					1216:1223	MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces	1133:1223	MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites	1133:1250	Also, Cs-Pc had a higher ability to remove MB than chitosan and pectin, probably due to its highly porous structure and rough surfaces that provides active sites and facilitate MB adsorption.					
36705863	9	78	theme	maximum	1286:1292	arg1	efficiency					1302:1311	maximum removal efficiency	1286:1311	maximum removal efficiency	1286:1311	The maximum removal efficiency and the adsorption capacity of MB onto Cs-Pc at 500 mg L-1 concentration under optimum conditions were 98.67% and 328.02 mg g-1, respectively.					
36705863	4	79	theme	Cs-Pc	569:573	arg1	dose					575:578	Cs-Pc dose	569:578	Cs-Pc dose	569:578	To evaluate the parameters affecting adsorption, including the initial MB concentration, solution pH, contact time, and Cs-Pc dose, batch experiments were carried out.					
36705863	13	80	theme	strong	1854:1859	arg1	capability					1871:1880	its strong adsorbing capability	1850:1880	its strong adsorbing capability	1850:1880	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	5	81	theme	pH	736:737	arg1	point					739:743	pH point	736:743	pH point of zero charges (pH pzc)	736:768	Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR), and pH point of zero charges (pH pzc) were applied for characterizations of Cs-Pc.					
36705863	13	82	theme	MB	1799:1800	arg1	removal					1802:1808	MB removal	1799:1808	MB removal from polluted solutions	1799:1832	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
36705863	1	83	theme	organic	153:159	arg1	compounds					161:169	organic compounds	153:169	organic compounds	153:169	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	1	83	theme	organic	153:159	arg1	dyes					182:185	dyes	182:185	dyes	182:185	Wastewater contains organic compounds, including dyes, which have potential risks to the environment.					
36705863	13	84	from	solutions	1824:1832	arg1	removal					1802:1808	MB removal	1799:1808	MB removal from polluted solutions	1799:1832	So the application of Cs-Pc is promising for MB removal from polluted solutions not only due to its strong adsorbing capability but also due to its excellent ability to reuse.					
37011752	2	0	theme	smaller	459:465	arg1	size					476:479	a smaller particle size	457:479	a smaller particle size	457:479	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	1	1	theme	Pickering	318:326	arg1	ability					340:346	its Pickering emulsifying ability	314:346	its Pickering emulsifying ability	314:346	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	2	theme	in-vitro	149:156	arg1	digestibility					158:170	in-vitro digestibility	149:170	in-vitro digestibility	149:170	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	4	3	theme	DPPH	828:831	arg1	scavenging					841:850	DPPH radical scavenging	828:850	DPPH radical scavenging	828:850	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	4	4	theme	corn	921:924	arg1	starch					926:931	corn starch	921:931	corn starch	921:931	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	1	5	theme	emulsifying	328:338	arg1	ability					340:346	its Pickering emulsifying ability	314:346	its Pickering emulsifying ability	314:346	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	2	6	theme	amylose	490:496	arg1	similar					536:542	similar	536:542	similar	536:542	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	6	theme	amylose	490:496	arg1	content					498:504	the amylose content	486:504	the amylose content	486:504	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	3	7	theme	acorn	582:586	arg1	difficult					599:607	difficult	599:607	difficult	599:607	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	3	7	theme	acorn	582:586	arg1	starch					588:593	the acorn starch	578:593	the acorn starch	578:593	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	2	8	theme	corn	556:559	arg1	starch					561:566	corn starch	556:566	corn starch	556:566	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	7	9	theme	acorn	1291:1295	arg1	starch					1297:1302	acorn starch	1291:1302	acorn starch	1291:1302	The obtained results may serve as a reference for the further development of acorn starch.					
37011752	5	10	theme	Acorn	934:938	arg1	starch					940:945	Acorn starch	934:945	Acorn starch	934:945	Acorn starch also exhibited outstanding particle wettability and could stabilize Pickering emulsions.					
37011752	2	11	dep	content	498:504	arg1	degree					524:529	degree	524:529	degree	524:529	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	12	from	shape	445:449	arg1	spherical					423:431	spherical	423:431	spherical	423:431	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	12	from	shape	445:449	arg1	granules					409:416	the acorn starch granules	392:416	the acorn starch granules	392:416	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	6	13	theme	starch	1190:1195	arg1	amount					1206:1211	the acorn starch addition amount	1180:1211	the acorn starch addition amount	1180:1211	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	4	14	theme	potato	903:908	arg1	starch					910:915	potato starch	903:915	potato starch	903:915	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	3	15	contain	had	659:661	arg2	strength					676:683	a strong gel strength	663:683	a strong gel strength	663:683	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	3	15	contain	had	659:661	arg1	it					656:657	it	656:657	it	656:657	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	3	15	contain	had	659:661	arg2	viscosity					697:705	setback viscosity	689:705	setback viscosity	689:705	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	4	16	theme	resistant	776:784	arg1	starch					786:791	its resistant starch	772:791	its resistant starch content after cooking	772:813	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	2	17	theme	starch	402:407	arg1	spherical					423:431	spherical	423:431	spherical	423:431	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	17	theme	starch	402:407	arg1	granules					409:416	the acorn starch granules	392:416	the acorn starch granules	392:416	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	4	18	theme	acorn	716:720	arg1	starch					722:727	acorn starch	716:727	acorn starch	716:727	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	6	19	theme	assessed	1040:1047	arg1	emulsion					1049:1056	The assessed emulsion	1036:1056	The assessed emulsion	1036:1056	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	1	20	theme	antioxidant	173:183	arg1	capacity					185:192	antioxidant capacity	173:192	antioxidant capacity	173:192	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	0	21	theme	physicochemical	4:18	arg1	properties					20:29	physicochemical properties	4:29	physicochemical properties	4:29	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	3	22	theme	strong	665:670	arg1	strength					676:683	a strong gel strength	663:683	a strong gel strength	663:683	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	7	23	theme	starch	1297:1302	arg1	development					1276:1286	the further development	1264:1286	the further development of acorn starch	1264:1302	The obtained results may serve as a reference for the further development of acorn starch.					
37011752	3	24	theme	aqueous	629:635	arg1	solubility					637:646	poor aqueous solubility	624:646	poor aqueous solubility	624:646	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	6	25	theme	acorn	1184:1188	arg1	amount					1206:1211	the acorn starch addition amount	1180:1211	the acorn starch addition amount	1180:1211	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	4	26	theme	starch	786:791	arg1	content					793:799	its resistant starch content	772:799	its resistant starch content after cooking	772:813	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	1	27	theme	potato	279:284	arg1	starch					286:291	potato starch	279:291	potato starch	279:291	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	6	28	theme	ultraviolet	1121:1131	arg1	irradiation					1133:1143	ultraviolet irradiation	1121:1143	ultraviolet irradiation	1121:1143	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	3	29	theme	gel	672:674	arg1	strength					676:683	a strong gel strength	663:683	a strong gel strength	663:683	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	3	30	with	difficult	599:607	arg1	solubility					637:646	poor aqueous solubility	624:646	poor aqueous solubility	624:646	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	1	31	theme	phenolic	199:206	arg1	composition					208:218	phenolic composition	199:218	phenolic composition	199:218	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	0	32	theme	emulsifying	45:55	arg1	capacity					57:64	Pickering emulsifying capacity	35:64	Pickering emulsifying capacity	35:64	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	7	33	theme	further	1268:1274	arg1	development					1276:1286	the further development	1264:1286	the further development of acorn starch	1264:1302	The obtained results may serve as a reference for the further development of acorn starch.					
37011752	4	34	theme	bound	753:757	arg1	polyphenols					759:769	more free and bound polyphenols	739:769	more free and bound polyphenols	739:769	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	2	35	theme	acorn	396:400	arg1	spherical					423:431	spherical	423:431	spherical	423:431	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	35	theme	acorn	396:400	arg1	granules					409:416	the acorn starch granules	392:416	the acorn starch granules	392:416	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	0	36	theme	Pickering	35:43	arg1	capacity					57:64	Pickering emulsifying capacity	35:64	Pickering emulsifying capacity	35:64	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	1	37	theme	corn	297:300	arg1	starch					302:307	corn starch	297:307	corn starch	297:307	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	5	38	theme	outstanding	962:972	arg1	wettability					983:993	outstanding particle wettability	962:993	outstanding particle wettability	962:993	Acorn starch also exhibited outstanding particle wettability and could stabilize Pickering emulsions.					
37011752	2	39	with	spherical	423:431	arg1	size					476:479	a smaller particle size	457:479	a smaller particle size	457:479	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	4	40	theme	ABTS	819:822	arg1	activities					852:861	ABTS and DPPH radical scavenging activities	819:861	ABTS and DPPH radical scavenging activities	819:861	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	0	41	theme	acorn	69:73	arg1	starch					75:80	acorn starch	69:80	acorn starch	69:80	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	5	42	theme	particle	974:981	arg1	wettability					983:993	outstanding particle wettability	962:993	outstanding particle wettability	962:993	Acorn starch also exhibited outstanding particle wettability and could stabilize Pickering emulsions.					
37011752	1	43	theme	granule	101:107	arg1	characteristics					109:123	the granule characteristics	97:123	the granule characteristics	97:123	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	3	44	theme	setback	689:695	arg1	viscosity					697:705	setback viscosity	689:705	setback viscosity	689:705	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	4	45	theme	scavenging	841:850	arg1	activities					852:861	ABTS and DPPH radical scavenging activities	819:861	ABTS and DPPH radical scavenging activities	819:861	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	3	46	theme	poor	624:627	arg1	solubility					637:646	poor aqueous solubility	624:646	poor aqueous solubility	624:646	However, the acorn starch was difficult to swell, with poor aqueous solubility, though it had a strong gel strength and setback viscosity.					
37011752	6	47	theme	addition	1197:1204	arg1	amount					1206:1211	the acorn starch addition amount	1180:1211	the acorn starch addition amount	1180:1211	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	1	48	theme	acorn	223:227	arg1	starch					229:234	acorn starch	223:234	acorn starch	223:234	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	4	49	theme	radical	833:839	arg1	scavenging					841:850	DPPH radical scavenging	828:850	DPPH radical scavenging	828:850	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	0	50	dep	properties	20:29	arg1	The					0:2	The	0:2	The	0:2	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	1	51	theme	functional	126:135	arg1	properties					137:146	functional properties	126:146	functional properties	126:146	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	52	theme	starch	229:234	arg1	capacity					185:192	antioxidant capacity	173:192	antioxidant capacity	173:192	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	52	theme	starch	229:234	arg1	composition					208:218	phenolic composition	199:218	phenolic composition	199:218	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	52	theme	starch	229:234	arg1	characteristics					109:123	the granule characteristics	97:123	the granule characteristics	97:123	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	52	theme	starch	229:234	arg1	properties					137:146	functional properties	126:146	functional properties	126:146	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	1	52	theme	starch	229:234	arg1	digestibility					158:170	in-vitro digestibility	149:170	in-vitro digestibility	149:170	In this work, the granule characteristics, functional properties, in-vitro digestibility, antioxidant capacity, and phenolic composition of acorn starch were investigated and compared to those of potato starch and corn starch, and its Pickering emulsifying ability was also evaluated.					
37011752	0	53	theme	starch	75:80	arg1	properties					20:29	physicochemical properties	4:29	physicochemical properties	4:29	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	0	53	theme	starch	75:80	arg1	capacity					57:64	Pickering emulsifying capacity	35:64	Pickering emulsifying capacity	35:64	The physicochemical properties and Pickering emulsifying capacity of acorn starch.					
37011752	5	54	theme	Pickering	1015:1023	arg1	emulsions					1025:1033	Pickering emulsions	1015:1033	Pickering emulsions	1015:1033	Acorn starch also exhibited outstanding particle wettability and could stabilize Pickering emulsions.					
37011752	4	55	theme	free	744:747	arg1	polyphenols					759:769	more free and bound polyphenols	739:769	more free and bound polyphenols	739:769	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	6	56	theme	outstanding	1068:1078	arg1	effect					1080:1085	an outstanding effect	1065:1085	an outstanding effect	1065:1085	The assessed emulsion showed an outstanding effect for protecting β-carotene against ultraviolet irradiation and was positively correlated with the acorn starch addition amount.					
37011752	7	57	theme	obtained	1218:1225	arg1	reference					1250:1258	a reference	1248:1258	a reference for the further development of acorn starch	1248:1302	The obtained results may serve as a reference for the further development of acorn starch.					
37011752	7	57	theme	obtained	1218:1225	arg1	results					1227:1233	The obtained results	1214:1233	The obtained results	1214:1233	The obtained results may serve as a reference for the further development of acorn starch.					
37011752	2	58	theme	particle	467:474	arg1	size					476:479	a smaller particle size	457:479	a smaller particle size	457:479	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	2	59	from	spherical	423:431	arg1	shape					445:449	shape	445:449	shape	445:449	The results showed that the acorn starch granules were spherical and oval in shape, with a smaller particle size, and the amylose content and crystallinity degree were similar to those of corn starch.					
37011752	4	60	contain	contained	729:737	arg1	starch					722:727	acorn starch	716:727	acorn starch	716:727	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37011752	4	60	contain	contained	729:737	arg2	polyphenols					759:769	more free and bound polyphenols	739:769	more free and bound polyphenols	739:769	Because acorn starch contained more free and bound polyphenols, its resistant starch content after cooking and ABTS and DPPH radical scavenging activities were significantly higher than those of potato starch and corn starch.					
37029312	4	0	from	6 h	1004:1006	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	0	from	6 h	1004:1006	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	0	from	6 h	1004:1006	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	1	theme	dependent	941:949	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	1	theme	dependent	941:949	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	1	theme	dependent	941:949	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	2	2	theme	dynamics	394:401	arg1	simulations					403:413	molecular dynamics simulations	384:413	molecular dynamics simulations	384:413	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	5	3	theme	Korsmeyer-Peppas	1225:1240	arg1	model					1251:1255	the Korsmeyer-Peppas kinetics model	1221:1255	the Korsmeyer-Peppas kinetics model	1221:1255	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	2	4	with	complex	346:352	arg1	HP-β-CD					359:365	HP-β-CD	359:365	HP-β-CD	359:365	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	7	5	contain	containing	1526:1535	arg2	complex					1576:1582	the ibuprofen-β-cyclodextrin inclusion complex	1537:1582	the ibuprofen-β-cyclodextrin inclusion complex with sustained release	1537:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	7	5	contain	containing	1526:1535	arg1	gel					1522:1524	a mucoadhesive gel	1507:1524	a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release	1507:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	6	6	theme	HPC-L	1312:1316	arg1	formulations					1318:1329	0.95% Carbopol 934P and 0.55% HPC-L formulations	1282:1329	0.95% Carbopol 934P and 0.55% HPC-L formulations	1282:1329	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	1	7	theme	freeze-drying	193:205	arg1	method					207:212	freeze-drying method	193:212	freeze-drying method	193:212	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	5	8	theme	kinetics	1242:1249	arg1	model					1251:1255	the Korsmeyer-Peppas kinetics model	1221:1255	the Korsmeyer-Peppas kinetics model	1221:1255	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	4	9	from	12 h	1012:1015	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	9	from	12 h	1012:1015	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	9	from	12 h	1012:1015	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	10	theme	independent	864:874	arg1	variables					876:884	two independent variables	860:884	two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	860:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	2	11	theme	inclusion	336:344	arg1	complex					346:352	The inclusion complex	332:352	The inclusion complex with HP-β-CD	332:365	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	7	12	theme	mucoadhesive	1509:1520	arg1	gel					1522:1524	a mucoadhesive gel	1507:1524	a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release	1507:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	4	13	theme	mucoadhesive	837:848	arg1	gel					850:852	the mucoadhesive gel	833:852	the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	833:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	3	14	dep	Carbopol	528:535	arg1	Ultrez					591:596	Ultrez	591:596	Ultrez	591:596	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	1	15	theme	X-ray	303:307	arg1	diffractograms					316:329	X-ray powder diffractograms	303:329	X-ray powder diffractograms	303:329	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	4	16	theme	composite	764:772	arg1	design					774:779	The central composite design	752:779	The central composite design generated by Design-Expert	752:806	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	17	theme	agents	924:929	arg1	combination					897:907	a varying combination	887:907	a varying combination of two gelling agents	887:929	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	5	18	dep	gels	1074:1077	arg1	%					1098:1098	1%	1097:1098	1%	1097:1098	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	5	18	dep	gels	1074:1077	arg1	%					1083:1083	0.5%	1080:1083	0.5%	1080:1083	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	5	18	dep	gels	1074:1077	arg1	%					1090:1090	0.75%	1086:1090	0.75%	1086:1090	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	0	19	theme	Experimental	110:121	arg1	Design					123:128	an Experimental Design	107:128	an Experimental Design	107:128	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.					
37029312	4	20	theme	gelling	916:922	arg1	agents					924:929	two gelling agents	912:929	two gelling agents	912:929	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	7	21	theme	inclusion	1566:1574	arg1	complex					1576:1582	the ibuprofen-β-cyclodextrin inclusion complex	1537:1582	the ibuprofen-β-cyclodextrin inclusion complex with sustained release	1537:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	3	22	theme	10	598:599	arg1	NF					601:602	NF	601:602	NF	601:602	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	6	23	theme	0.55	1306:1309	arg1	%					1310:1310	%	1310:1310	%	1310:1310	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	2	24	theme	aqueous	429:435	arg1	solubility					437:446	the aqueous solubility	425:446	the aqueous solubility of ibuprofen	425:459	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	6	25	theme	test	1269:1272	arg1	design					1274:1279	this test design	1264:1279	this test design	1264:1279	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	5	26	theme	ibuprofen	1164:1172	arg1	extended-release					1144:1159	an extended-release	1141:1159	an extended-release	1141:1159	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	3	27	theme	derivatives	619:629	arg1	grades					518:523	Different grades	508:523	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	508:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	6	28	theme	0.95	1282:1285	arg1	%					1286:1286	%	1286:1286	%	1286:1286	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	4	29	dep	variables	876:884	arg1	combination					897:907	a varying combination	887:907	a varying combination of two gelling agents	887:929	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	0	30	theme	Inclusion	0:8	arg1	Complex					10:16	Inclusion Complex	0:16	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.	0:129	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.					
37029312	1	31	theme	powder	309:314	arg1	diffractograms					316:329	X-ray powder diffractograms	303:329	X-ray powder diffractograms	303:329	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	0	32	theme	Ibuprofen-β-Cyclodextrin	21:44	arg1	Complex					10:16	Inclusion Complex	0:16	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.	0:129	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.					
37029312	4	33	theme	drug	988:991	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	33	theme	drug	988:991	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	7	34	theme	ibuprofen-β-cyclodextrin	1541:1564	arg1	complex					1576:1582	the ibuprofen-β-cyclodextrin inclusion complex	1537:1582	the ibuprofen-β-cyclodextrin inclusion complex with sustained release	1537:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	6	35	from	studies	1457:1463	arg1	non-irritating					1406:1419	non-irritating	1406:1419	non-irritating	1406:1419	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	1	36	theme	phase	236:240	arg1	profiles					253:260	phase solubility profiles	236:260	phase solubility profiles	236:260	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	2	37	theme	molecular	384:392	arg1	simulations					403:413	molecular dynamics simulations	384:413	molecular dynamics simulations	384:413	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	1	38	theme	solubility	242:251	arg1	profiles					253:260	phase solubility profiles	236:260	phase solubility profiles	236:260	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	6	39	theme	ibuprofen	1358:1366	arg1	release					1368:1374	ibuprofen release	1358:1374	ibuprofen release	1358:1374	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	6	40	theme	934P	1297:1300	arg1	formulations					1318:1329	0.95% Carbopol 934P and 0.55% HPC-L formulations	1282:1329	0.95% Carbopol 934P and 0.55% HPC-L formulations	1282:1329	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	6	41	theme	ex	1424:1425	arg1	studies					1457:1463	ex vivo chorioallantoic membrane studies	1424:1463	ex vivo chorioallantoic membrane studies	1424:1463	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	3	42	theme	K15M/HPMC	648:656	arg1	derivatives					619:629	cellulose derivatives	609:629	cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	609:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	42	theme	K15M/HPMC	648:656	arg1	E15LV/HPC					667:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	2	43	theme	ibuprofen	451:459	arg1	solubility					437:446	the aqueous solubility	425:446	the aqueous solubility of ibuprofen	425:459	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	4	44	dep	variables	951:959	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	44	dep	variables	951:959	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	44	dep	variables	951:959	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	6	45	theme	Carbopol	1288:1295	arg1	934P					1297:1300	0.95% Carbopol 934P	1282:1300	0.95% Carbopol 934P	1282:1300	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	6	46	from	non-irritating	1406:1419	arg1	studies					1457:1463	ex vivo chorioallantoic membrane studies	1424:1463	ex vivo chorioallantoic membrane studies	1424:1463	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	3	47	theme	K4M/HPMC	658:665	arg1	derivatives					619:629	cellulose derivatives	609:629	cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	609:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	47	theme	K4M/HPMC	658:665	arg1	E15LV/HPC					667:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	6	48	dep	ex	1424:1425	arg1	vivo					1427:1430	vivo	1427:1430	vivo	1427:1430	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	6	49	theme	%	1310:1310	arg1	HPC-L					1312:1316	0.55% HPC-L	1306:1316	0.55% HPC-L	1306:1316	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	6	50	theme	%	1286:1286	arg1	934P					1297:1300	0.95% Carbopol 934P	1282:1300	0.95% Carbopol 934P	1282:1300	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	3	51	theme	mucoadhesive	697:708	arg1	gels					710:713	mucoadhesive gels	697:713	mucoadhesive gels incorporating the inclusion complex	697:749	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	52	theme	HPMC	632:635	arg1	derivatives					619:629	cellulose derivatives	609:629	cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	609:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	52	theme	HPMC	632:635	arg1	E15LV/HPC					667:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	4	53	theme	drug	962:965	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	53	theme	drug	962:965	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	5	54	dep	74	1194:1195	arg1	to					1191:1192	to	1191:1192	to	1191:1192	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	3	55	theme	K100M/HPMC	637:646	arg1	derivatives					619:629	cellulose derivatives	609:629	cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	609:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	55	theme	K100M/HPMC	637:646	arg1	E15LV/HPC					667:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	1	56	theme	β-Cyclodextrin/ibuprofen	131:154	arg1	complex					166:172	β-Cyclodextrin/ibuprofen inclusion complex	131:172	β-Cyclodextrin/ibuprofen inclusion complex	131:172	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	4	57	theme	in	979:980	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	57	theme	in	979:980	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	5	58	theme	methylcellulose-based	1034:1054	arg1	gels					1056:1059	the methylcellulose-based gels	1030:1059	the methylcellulose-based gels	1030:1059	Except for the methylcellulose-based gels, most of the gels (0.5%, 0.75%, and 1% alone or as a mixture thereof) exhibited an extended-release of ibuprofen, ranging from 40 to 74% over 24 h and followed the Korsmeyer-Peppas kinetics model.					
37029312	4	59	theme	varying	889:895	arg1	combination					897:907	a varying combination	887:907	a varying combination of two gelling agents	887:929	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	1	60	theme	inclusion	156:164	arg1	complex					166:172	β-Cyclodextrin/ibuprofen inclusion complex	131:172	β-Cyclodextrin/ibuprofen inclusion complex	131:172	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	1	61	theme	infrared	263:270	arg1	spectra					272:278	infrared spectra	263:278	infrared spectra	263:278	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
37029312	7	62	with	complex	1576:1582	arg1	release					1599:1605	sustained release	1589:1605	sustained release	1589:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	7	63	theme	present	1470:1476	arg1	study					1478:1482	The present study	1466:1482	The present study	1466:1482	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	2	64	dep	enhanced	416:423	arg1	confirmed					371:379	confirmed	371:379	confirmed by molecular dynamics simulations	371:413	The inclusion complex with HP-β-CD, as confirmed by molecular dynamics simulations, enhanced the aqueous solubility of ibuprofen by almost 30-fold compared to ibuprofen alone.					
37029312	3	65	theme	Carbopol	528:535	arg1	grades					518:523	Different grades	508:523	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	508:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	66	theme	cellulose	609:617	arg1	derivatives					619:629	cellulose derivatives	609:629	cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	609:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	3	66	theme	cellulose	609:617	arg1	E15LV/HPC					667:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC	632:675	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	4	67	dep	in	979:980	arg1	vitro					982:986	vitro	982:986	vitro	982:986	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	3	68	theme	inclusion	733:741	arg1	complex					743:749	the inclusion complex	729:749	the inclusion complex	729:749	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	0	69	dep	Complex	10:16	arg1	Optimization					88:99	Optimization	88:99	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.	0:129	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.					
37029312	3	70	theme	Different	508:516	arg1	grades					518:523	Different grades	508:523	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC)	508:676	Different grades of Carbopol (Carbopol 934P/Carbopol 974P/Carbopol 980 NF/Carbopol Ultrez 10 NF) and cellulose derivatives (HPMC K100M/HPMC K15M/HPMC K4M/HPMC E15LV/HPC) were evaluated for mucoadhesive gels incorporating the inclusion complex.					
37029312	4	71	theme	central	756:762	arg1	design					774:779	The central composite design	752:779	The central composite design generated by Design-Expert	752:806	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	6	72	theme	membrane	1448:1455	arg1	studies					1457:1463	ex vivo chorioallantoic membrane studies	1424:1463	ex vivo chorioallantoic membrane studies	1424:1463	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	0	73	theme	Mucosal	70:76	arg1	Delivery					78:85	Mucosal Delivery	70:85	Mucosal Delivery	70:85	Inclusion Complex of Ibuprofen-β-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design.					
37029312	7	74	theme	sustained	1589:1597	arg1	release					1599:1605	sustained release	1589:1605	sustained release	1589:1605	The present study successfully developed a mucoadhesive gel containing the ibuprofen-β-cyclodextrin inclusion complex with sustained release.					
37029312	4	75	from	variables	876:884	arg1	release					993:999	in vitro drug release	979:999	in vitro drug release	979:999	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	75	from	variables	876:884	arg1	variables					951:959	three dependent variables	935:959	three dependent variables (drug content and in vitro drug release at 6 h and 12 h)	935:1016	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	4	75	from	variables	876:884	arg1	content					967:973	drug content	962:973	drug content	962:973	The central composite design generated by Design-Expert was employed to optimize the mucoadhesive gel using two independent variables (a varying combination of two gelling agents) on three dependent variables (drug content and in vitro drug release at 6 h and 12 h).					
37029312	6	76	theme	chorioallantoic	1432:1446	arg1	studies					1457:1463	ex vivo chorioallantoic membrane studies	1424:1463	ex vivo chorioallantoic membrane studies	1424:1463	Using this test design, 0.95% Carbopol 934P and 0.55% HPC-L formulations were optimized to increase ibuprofen release, enhance mucoadhesion, and be non-irritating in ex vivo chorioallantoic membrane studies.					
37029312	1	77	theme	thermal	281:287	arg1	analysis					289:296	thermal analysis	281:296	thermal analysis	281:296	β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms.					
36093331	1	0	from	understanding	233:245	arg1	N-glycans					269:277	its N-glycans	265:277	its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances	265:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	6	1	gly	glycosylation	1152:1164	arg1	patients					1179:1186	influenza patients	1169:1186	influenza patients	1169:1186	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	1	2	theme	changes	254:260	arg1	understanding					233:245	an understanding	230:245	an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances	230:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	7	3	from	survivors	1492:1500	arg1	consequence					1536:1546	the consequence	1532:1546	the consequence of an adequate immune response to enveloped viruses	1532:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	3	from	survivors	1492:1500	arg1	similarity					1440:1449	The similarity	1436:1449	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients	1436:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	1	4	theme	combatting	164:173	arg1	diseases					186:193	combatting infectious diseases	164:193	combatting infectious diseases	164:193	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	7	5	from	changes	1472:1478	arg1	survivors					1492:1500	COVID-19 survivors	1483:1500	COVID-19 survivors	1483:1500	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	5	from	changes	1472:1478	arg1	patients					1516:1523	influenza patients	1506:1523	influenza patients	1506:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	4	6	dep	GlcNAc	914:919	arg1	shows					939:943	shows	939:943	shows the most significant decrease	939:973	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	7	theme	IgG	532:534	arg1	glycome-at					536:545	the total IgG glycome-at	522:545	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	4	8	from	GlcNAc	914:919	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	4	9	theme	COVID-19	988:995	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	7	10	from	changes	1620:1626	arg1	patients					1649:1656	deceased COVID-19 patients	1631:1656	deceased COVID-19 patients	1631:1656	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	11	theme	immune	1563:1568	arg1	response					1570:1577	an adequate immune response	1551:1577	an adequate immune response to enveloped viruses	1551:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	4	12	theme	IgG	866:868	arg1	galactosylation					870:884	IgG galactosylation	866:884	IgG galactosylation	866:884	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	6	13	theme	influenza	1169:1177	arg1	patients					1179:1186	influenza patients	1169:1186	influenza patients	1169:1186	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	6	14	theme	disease	1244:1250	arg1	days					1232:1235	the first seven days	1216:1235	the first seven days of the disease	1216:1250	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	4	15	from	decrease	854:861	arg1	GlcNAc					914:919	bisecting GlcNAc	904:919	bisecting GlcNAc (where the latter shows the most significant decrease)	904:974	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	4	15	from	decrease	854:861	arg1	sialylation					887:897	sialylation	887:897	sialylation	887:897	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	4	15	from	decrease	854:861	arg1	galactosylation					870:884	IgG galactosylation	866:884	IgG galactosylation	866:884	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	16	theme	glycosylation	601:613	arg1	traits					615:620	derived glycosylation traits	593:620	derived glycosylation traits	593:620	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	17	theme	coronavirus	759:769	arg1	disease					771:777	coronavirus disease 2019	759:782	coronavirus disease 2019 (COVID-19)	759:793	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	17	theme	coronavirus	759:769	arg1	COVID-19					785:792	COVID-19	785:792	COVID-19	785:792	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	1	18	theme	Fc	317:318	arg1	domain					320:325	the Fc domain	313:325	the Fc domain that occur under such circumstances	313:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	1	19	theme	immune	135:140	arg1	system					142:147	immune system regulation and combatting infectious diseases	135:193	system	142:147	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	4	20	theme	bisecting	904:912	arg1	GlcNAc					914:919	bisecting GlcNAc	904:919	bisecting GlcNAc (where the latter shows the most significant decrease)	904:974	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	0	21	from	Differences	0:10	arg1	Glycosylation					32:44	Immunoglobulin G Glycosylation	15:44	Immunoglobulin G Glycosylation	15:44	Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients.					
36093331	3	22	with	patients	745:752	arg1	influenza					731:739	influenza	731:739	influenza	731:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	22	with	patients	745:752	arg1	disease					771:777	coronavirus disease 2019	759:782	coronavirus disease 2019 (COVID-19)	759:793	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	22	with	patients	745:752	arg1	COVID-19					785:792	COVID-19	785:792	COVID-19	785:792	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	23	with	controls	811:818	arg1	influenza					731:739	influenza	731:739	influenza	731:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	23	with	controls	811:818	arg1	disease					771:777	coronavirus disease 2019	759:782	coronavirus disease 2019 (COVID-19)	759:793	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	23	with	controls	811:818	arg1	COVID-19					785:792	COVID-19	785:792	COVID-19	785:792	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	7	24	theme	deceased	1631:1638	arg1	patients					1649:1656	deceased COVID-19 patients	1631:1656	deceased COVID-19 patients	1631:1656	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	1	25	dep	system	142:147	arg1	regulation					149:158	regulation	149:158	regulation	149:158	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	3	26	link	derived	593:599	arg1	traits					615:620	derived glycosylation traits	593:620	derived glycosylation traits	593:620	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	0	27	theme	Immunoglobulin	15:28	arg1	Glycosylation					32:44	Immunoglobulin G Glycosylation	15:44	Immunoglobulin G Glycosylation	15:44	Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients.					
36093331	7	28	from	patients	1516:1523	arg1	consequence					1536:1546	the consequence	1532:1546	the consequence of an adequate immune response to enveloped viruses	1532:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	28	from	patients	1516:1523	arg1	similarity					1440:1449	The similarity	1436:1449	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients	1436:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	1	29	theme	immunoglobulin	109:122	arg1	IgG					127:129	IgG	127:129	IgG	127:129	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	1	29	theme	immunoglobulin	109:122	arg1	G					124:124	immunoglobulin G	109:124	immunoglobulin G (IgG)	109:130	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	4	30	dep	revealed	831:838	arg1	whereas					1007:1013	whereas	1007:1013	whereas	1007:1013	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	1	31	theme	asparagine	295:304	arg1	297					306:308	the asparagine 297	291:308	the asparagine 297 of the Fc domain that occur under such circumstances	291:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	0	32	dep	Influenza	54:62	arg1	Patients					77:84	Patients	77:84	Patients	77:84	Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients.					
36093331	5	33	theme	influenza	1105:1113	arg1	patients					1115:1122	influenza patients	1105:1122	influenza patients	1105:1122	On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors.					
36093331	7	34	theme	glycosylation	1458:1470	arg1	changes					1472:1478	IgG glycosylation changes	1454:1478	IgG glycosylation changes in COVID-19 survivors and influenza patients	1454:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	1	35	from	role	101:104	arg1	diseases					186:193	combatting infectious diseases	164:193	combatting infectious diseases	164:193	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	1	35	from	role	101:104	arg1	system					142:147	immune system regulation and combatting infectious diseases	135:193	system	142:147	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	3	36	dep	patients	717:724	arg1	sialylation					623:633	sialylation	623:633	sialylation	623:633	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	36	dep	patients	717:724	arg1	N-acetylglucosamine					681:699	bisecting N-acetylglucosamine	671:699	bisecting N-acetylglucosamine (GlcNAc)	671:708	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	36	dep	patients	717:724	arg1	patients					717:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients	522:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	36	dep	patients	717:724	arg1	galactosylation					636:650	galactosylation	636:650	galactosylation	636:650	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	36	dep	patients	717:724	arg1	fucosylation					653:664	fucosylation	653:664	fucosylation	653:664	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	36	dep	patients	717:724	arg1	GlcNAc					702:707	GlcNAc	702:707	GlcNAc	702:707	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	4	37	theme	IgG	1015:1017	arg1	fucosylation					1019:1030	IgG fucosylation	1015:1030	IgG fucosylation	1015:1030	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	38	theme	bisecting	671:679	arg1	N-acetylglucosamine					681:699	bisecting N-acetylglucosamine	671:699	bisecting N-acetylglucosamine (GlcNAc)	671:708	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	38	theme	bisecting	671:679	arg1	patients					717:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients	522:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	38	theme	bisecting	671:679	arg1	GlcNAc					702:707	GlcNAc	702:707	GlcNAc	702:707	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	1	39	attach	attached	279:286	arg2	N-glycans					269:277	its N-glycans	265:277	its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances	265:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	1	39	attach	attached	279:286	arg1	297					306:308	the asparagine 297	291:308	the asparagine 297 of the Fc domain that occur under such circumstances	291:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	6	40	theme	bisecting	1401:1409	arg1	GlcNAc					1411:1416	bisecting GlcNAc	1401:1416	bisecting GlcNAc	1401:1416	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	3	41	theme	-of	710:712	arg1	N-acetylglucosamine					681:699	bisecting N-acetylglucosamine	671:699	bisecting N-acetylglucosamine (GlcNAc)	671:708	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	41	theme	-of	710:712	arg1	sialylation					623:633	sialylation	623:633	sialylation	623:633	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	41	theme	-of	710:712	arg1	fucosylation					653:664	fucosylation	653:664	fucosylation	653:664	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	41	theme	-of	710:712	arg1	patients					717:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients	522:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	41	theme	-of	710:712	arg1	galactosylation					636:650	galactosylation	636:650	galactosylation	636:650	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	6	42	theme	first	1220:1224	arg1	days					1232:1235	the first seven days	1216:1235	the first seven days of the disease	1216:1250	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	1	43	from	changes	254:260	arg1	N-glycans					269:277	its N-glycans	265:277	its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances	265:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	1	44	from	N-glycans	269:277	arg1	understanding					233:245	an understanding	230:245	an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances	230:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	3	45	theme	glycome-at	536:545	arg1	N-acetylglucosamine					681:699	bisecting N-acetylglucosamine	671:699	bisecting N-acetylglucosamine (GlcNAc)	671:708	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	45	theme	glycome-at	536:545	arg1	sialylation					623:633	sialylation	623:633	sialylation	623:633	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	45	theme	glycome-at	536:545	arg1	fucosylation					653:664	fucosylation	653:664	fucosylation	653:664	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	45	theme	glycome-at	536:545	arg1	patients					717:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients	522:724	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	45	theme	glycome-at	536:545	arg1	galactosylation					636:650	galactosylation	636:650	galactosylation	636:650	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	1	46	theme	infectious	175:184	arg1	diseases					186:193	combatting infectious diseases	164:193	combatting infectious diseases	164:193	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	6	47	theme	bisecting	1296:1304	arg1	GlcNAc					1306:1311	bisecting GlcNAc	1296:1311	bisecting GlcNAc	1296:1311	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	3	48	theme	total	526:530	arg1	glycome-at					536:545	the total IgG glycome-at	522:545	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	7	49	theme	enveloped	1582:1590	arg1	viruses					1592:1598	enveloped viruses	1582:1598	enveloped viruses	1582:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	4	50	from	sialylation	887:897	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	51	theme	individual	560:569	arg1	structures					578:587	individual glycan structures	560:587	individual glycan structures	560:587	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	7	52	theme	response	1570:1577	arg1	consequence					1536:1546	the consequence	1532:1546	the consequence of an adequate immune response to enveloped viruses	1532:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	52	theme	response	1570:1577	arg1	similarity					1440:1449	The similarity	1436:1449	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients	1436:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	6	53	theme	increased	1265:1273	arg1	sialylation					1253:1263	sialylation increased	1253:1273	sialylation increased	1253:1273	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	4	54	from	galactosylation	870:884	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	1	55	theme	G	124:124	arg1	role					101:104	The essential role	87:104	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases	87:193	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	7	56	from	similarity	1440:1449	arg1	survivors					1492:1500	COVID-19 survivors	1483:1500	COVID-19 survivors	1483:1500	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	56	from	similarity	1440:1449	arg1	patients					1516:1523	influenza patients	1506:1523	influenza patients	1506:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	57	theme	adequate	1554:1561	arg1	response					1570:1577	an adequate immune response	1551:1577	an adequate immune response to enveloped viruses	1551:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	4	58	theme	significant	842:852	arg1	decrease					854:861	a significant decrease	840:861	a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients	840:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	59	theme	derived	593:599	arg1	traits					615:620	derived glycosylation traits	593:620	derived glycosylation traits	593:620	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	4	60	gly	sialylation	887:897	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	3	61	theme	structures	578:587	arg1	level					551:555	the level	547:555	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	62	theme	healthy	803:809	arg1	controls					811:818	56 healthy controls	800:818	56 healthy controls	800:818	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	6	63	theme	IgG	1148:1150	arg1	glycosylation					1152:1164	IgG glycosylation	1148:1164	IgG glycosylation in influenza patients	1148:1186	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	6	64	from	glycosylation	1152:1164	arg1	patients					1179:1186	influenza patients	1169:1186	influenza patients	1169:1186	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	6	65	theme	next	1331:1334	arg1	days					1339:1342	the next 21 days	1327:1342	the next 21 days	1327:1342	IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable).					
36093331	1	66	theme	domain	320:325	arg1	297					306:308	the asparagine 297	291:308	the asparagine 297 of the Fc domain that occur under such circumstances	291:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	3	67	dep	glycome-at	536:545	arg1	level					551:555	the level	547:555	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	7	68	theme	influenza	1506:1514	arg1	patients					1516:1523	influenza patients	1506:1523	influenza patients	1506:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	1	69	theme	such	344:347	arg1	circumstances					349:361	such circumstances	344:361	such circumstances	344:361	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	3	70	with	patients	717:724	arg1	influenza					731:739	influenza	731:739	influenza	731:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	70	with	patients	717:724	arg1	disease					771:777	coronavirus disease 2019	759:782	coronavirus disease 2019 (COVID-19)	759:793	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	3	70	with	patients	717:724	arg1	COVID-19					785:792	COVID-19	785:792	COVID-19	785:792	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	1	71	theme	essential	91:99	arg1	role					101:104	The essential role	87:104	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases	87:193	The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances.					
36093331	7	72	theme	COVID-19	1640:1647	arg1	patients					1649:1656	deceased COVID-19 patients	1631:1656	deceased COVID-19 patients	1631:1656	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	0	73	theme	G	30:30	arg1	Glycosylation					32:44	Immunoglobulin G Glycosylation	15:44	Immunoglobulin G Glycosylation	15:44	Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients.					
36093331	5	74	theme	COVID-19	1128:1135	arg1	survivors					1137:1145	COVID-19 survivors	1128:1145	COVID-19 survivors	1128:1145	On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors.					
36093331	4	75	theme	deceased	979:986	arg1	patients					997:1004	deceased COVID-19 patients	979:1004	deceased COVID-19 patients	979:1004	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	5	76	theme	IgG	1066:1068	arg1	galactosylation					1070:1084	IgG galactosylation	1066:1084	IgG galactosylation	1066:1084	On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors.					
36093331	7	77	theme	observed	1611:1618	arg1	changes					1620:1626	the observed changes	1607:1626	the observed changes in deceased COVID-19 patients	1607:1656	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	2	78	theme	effector	451:458	arg1	functions					460:468	effector functions	451:468	effector functions	451:468	These glycans impact the antibody stability, half-life, secretion, immunogenicity, and effector functions.					
36093331	3	79	theme	traits	615:620	arg1	level					551:555	the level	547:555	the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza	522:739	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	2	80	theme	antibody	389:396	arg1	stability					398:406	the antibody stability	385:406	the antibody stability	385:406	These glycans impact the antibody stability, half-life, secretion, immunogenicity, and effector functions.					
36093331	7	81	theme	COVID-19	1483:1490	arg1	survivors					1492:1500	COVID-19 survivors	1483:1500	COVID-19 survivors	1483:1500	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	5	82	theme	other	1054:1058	arg1	hand					1060:1063	the other hand	1050:1063	the other hand	1050:1063	On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors.					
36093331	4	83	theme	significant	954:964	arg1	decrease					966:973	the most significant decrease	945:973	the most significant decrease	945:973	Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased.					
36093331	7	84	theme	changes	1472:1478	arg1	consequence					1536:1546	the consequence	1532:1546	the consequence of an adequate immune response to enveloped viruses	1532:1598	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	7	84	theme	changes	1472:1478	arg1	similarity					1440:1449	The similarity	1436:1449	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients	1436:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
36093331	3	85	theme	glycan	571:576	arg1	structures					578:587	individual glycan structures	560:587	individual glycan structures	560:587	Therefore, in this study, we analyzed and compared the total IgG glycome-at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))-of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls.					
36093331	7	86	theme	IgG	1454:1456	arg1	changes					1472:1478	IgG glycosylation changes	1454:1478	IgG glycosylation changes in COVID-19 survivors and influenza patients	1454:1523	The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.					
35261128	9	0	with	broth	1046:1050	arg1	casitone					1079:1086	0.019% casitone	1072:1086	0.019% casitone	1072:1086	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	%					1060:1060	1.0%	1057:1060	1.0% Tween 80	1057:1069	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	1.65 μg ml-1					1142:1153	1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT	1142:1191	1.65 μg ml-1	1142:1153	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	%					1092:1092	1.4% bacteriological agar	1089:1113	1.4% bacteriological agar	1089:1113	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	yolk					1124:1127	10% egg yolk	1116:1127	10% egg yolk	1116:1127	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	STUDY					1200:1204	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	0	with	broth	1046:1050	arg1	%					1132:1132	10% ADC	1130:1136	10% ADC	1130:1136	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	4	1	dep	METHODS	286:292	arg1	factors					333:339	factors	333:339	factors	333:339	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	4	1	dep	METHODS	286:292	arg1	constituents					319:330	Seven medium constituents	306:330	METHODS AND RESULTS Seven medium constituents (factors)	286:340	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	7	2	theme	streak	840:845	arg1	plates					847:852	streak plates	840:852	streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	840:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	6	3	theme	individual	589:598	arg1	factors					600:606	individual factors	589:606	individual factors	589:606	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	0	4	theme	Mycobacterium	62:74	arg1	subsp					82:86	Mycobacterium avium subsp	62:86	Mycobacterium avium subsp	62:86	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	9	5	theme	bacteriological	1094:1108	arg1	agar					1110:1113	bacteriological agar	1094:1113	1.4% bacteriological agar	1089:1113	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	6	6	theme	new	785:787	arg1	medium					803:808	a new solid culture medium	783:808	a new solid culture medium	783:808	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	7	theme	0.019	1072:1076	arg1	%					1077:1077	%	1077:1077	%	1077:1077	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	6	8	theme	multiple	740:747	arg1	factors					749:755	multiple factors	740:755	multiple factors	740:755	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	7	9	theme	earlier	892:898	arg1	2 weeks					884:890	the optimized solid medium 2 weeks	857:890	the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	857:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	6	10	dep	design	632:637	arg1	design					698:703	central composite design	680:703	central composite design	680:703	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	7	11	theme	yolk	922:925	arg1	medium					927:932	Herrold's egg yolk medium	908:932	Herrold's egg yolk medium (HEYM)	908:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	7	11	theme	yolk	922:925	arg1	HEYM					935:938	HEYM	935:938	HEYM	935:938	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	9	12	theme	Mycobactin	1155:1164	arg1	SIGNIFICANCE					1169:1180	Mycobactin J. SIGNIFICANCE	1155:1180	Mycobactin J. SIGNIFICANCE	1155:1180	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	13	theme	J.	1166:1167	arg1	SIGNIFICANCE					1169:1180	Mycobactin J. SIGNIFICANCE	1155:1180	Mycobactin J. SIGNIFICANCE	1155:1180	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	10	14	theme	MAP	1345:1347	arg1	culture					1349:1355	MAP culture	1345:1355	MAP culture	1345:1355	The new medium could improve MAP culture in future by reducing incubation times and increasing MAP colony numbers.					
35261128	9	15	dep	%	1060:1060	arg1	Tween					1062:1066	Tween	1062:1066	Tween	1062:1066	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	7	16	theme	MAP	811:813	arg1	growth					815:820	MAP growth	811:820	MAP growth	811:820	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	6	17	theme	surface	654:660	arg1	methodology					662:672	a response surface methodology	643:672	a response surface methodology (RSM)	643:678	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	17	theme	surface	654:660	arg1	RSM					675:677	RSM	675:677	RSM	675:677	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	8	18	dep	CONCLUSIONS	942:952	arg1	MAP					954:956	MAP	954:956	MAP	954:956	CONCLUSIONS MAP grew faster on the optimized solid medium than on HEYM.					
35261128	8	19	theme	optimized	977:985	arg1	medium					993:998	the optimized solid medium	973:998	the optimized solid medium	973:998	CONCLUSIONS MAP grew faster on the optimized solid medium than on HEYM.					
35261128	6	20	theme	factors	749:755	arg1	effects					729:735	the effects	725:735	the effects of multiple factors	725:755	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	21	theme	egg	1120:1122	arg1	yolk					1124:1127	10% egg yolk	1116:1127	10% egg yolk	1116:1127	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	5	22	theme	OADC	535:538	arg1	supplement					547:556	either OADC or ADC supplement	528:556	either OADC or ADC supplement	528:556	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	5	22	theme	OADC	535:538	arg1	Tween					457:461	Tween	457:461	Tween	457:461	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	6	23	theme	initial	568:574	arg1	screening					576:584	an initial screening	565:584	an initial screening of individual factors	565:606	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	4	24	theme	various	359:365	arg1	concentrations					367:380	various concentrations	359:380	various concentrations for their ability to positively affect MAP growth	359:430	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	5	25	theme	taurocholic	487:497	arg1	acid					499:502	taurocholic acid	487:502	taurocholic acid	487:502	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	5	25	theme	taurocholic	487:497	arg1	Tween					457:461	Tween	457:461	Tween	457:461	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	7	26	theme	2 weeks	884:890	arg1	plates					847:852	streak plates	840:852	streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	840:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	9	27	dep	1.65 μg ml-1	1142:1153	arg1	SIGNIFICANCE					1169:1180	Mycobactin J. SIGNIFICANCE	1155:1180	Mycobactin J. SIGNIFICANCE	1155:1180	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	8	28	theme	solid	987:991	arg1	medium					993:998	the optimized solid medium	973:998	the optimized solid medium	973:998	CONCLUSIONS MAP grew faster on the optimized solid medium than on HEYM.					
35261128	5	29	theme	ADC	543:545	arg1	supplement					547:556	either OADC or ADC supplement	528:556	either OADC or ADC supplement	528:556	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	5	29	theme	ADC	543:545	arg1	Tween					457:461	Tween	457:461	Tween	457:461	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	0	30	dep	Mycobacterium	62:74	arg1	avium					76:80	avium	76:80	avium	76:80	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	6	31	theme	response	645:652	arg1	methodology					662:672	a response surface methodology	643:672	a response surface methodology (RSM)	643:678	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	31	theme	response	645:652	arg1	RSM					675:677	RSM	675:677	RSM	675:677	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	32	theme	solid	1286:1290	arg1	medium					1292:1297	a solid medium	1284:1297	a solid medium for MAP culture	1284:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	0	33	theme	composition	20:30	arg1	Optimization					0:11	Optimization	0:11	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.	0:87	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	7	34	theme	solid	871:875	arg1	2 weeks					884:890	the optimized solid medium 2 weeks	857:890	the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	857:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	7	35	theme	medium	877:882	arg1	2 weeks					884:890	the optimized solid medium 2 weeks	857:890	the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	857:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	9	36	theme	medium	1292:1297	arg1	composition					1269:1279	the composition	1265:1279	the composition of a solid medium for MAP culture	1265:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	6	37	theme	composite	688:696	arg1	design					698:703	central composite design	680:703	central composite design	680:703	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	38	theme	STUDY	1200:1204	arg1	casitone					1079:1086	0.019% casitone	1072:1086	0.019% casitone	1072:1086	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	%					1060:1060	1.0%	1057:1060	1.0% Tween 80	1057:1069	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	IMPACT					1186:1191	IMPACT	1186:1191	IMPACT	1186:1191	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	1.65 μg ml-1					1142:1153	1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT	1142:1191	1.65 μg ml-1	1142:1153	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	%					1092:1092	1.4% bacteriological agar	1089:1113	1.4% bacteriological agar	1089:1113	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	yolk					1124:1127	10% egg yolk	1116:1127	10% egg yolk	1116:1127	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	STUDY					1200:1204	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	38	theme	STUDY	1200:1204	arg1	%					1132:1132	10% ADC	1130:1136	10% ADC	1130:1136	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	7	39	theme	egg	918:920	arg1	medium					927:932	Herrold's egg yolk medium	908:932	Herrold's egg yolk medium (HEYM)	908:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	7	39	theme	egg	918:920	arg1	HEYM					935:938	HEYM	935:938	HEYM	935:938	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	2	40	theme	optimized	181:189	arg1	medium					205:210	an optimized solid culture medium	178:210	an optimized solid culture medium for improved growth of Mycobacterium avium subsp	178:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	5	41	theme	egg	467:469	arg1	yolk					471:474	egg yolk	467:474	egg yolk	467:474	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	5	41	theme	egg	467:469	arg1	Tween					457:461	Tween	457:461	Tween	457:461	The factors tested were Tween 80, egg yolk, casitone, taurocholic acid, Mycobactin J, agar and either OADC or ADC supplement.					
35261128	9	42	dep	%	1092:1092	arg1	agar					1110:1113	bacteriological agar	1094:1113	1.4% bacteriological agar	1089:1113	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	43	theme	10	1116:1117	arg1	%					1118:1118	%	1118:1118	%	1118:1118	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	2	44	theme	Mycobacterium	235:247	arg1	subsp					255:259	Mycobacterium avium subsp	235:259	Mycobacterium avium subsp	235:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	9	45	theme	Middlebrook	1030:1040	arg1	broth					1046:1050	Middlebrook 7H9 broth	1030:1050	Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1030:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	2	46	dep	Mycobacterium	235:247	arg1	avium					249:253	avium	249:253	avium	249:253	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	9	47	theme	%	1118:1118	arg1	yolk					1124:1127	10% egg yolk	1116:1127	10% egg yolk	1116:1127	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	10	48	theme	colony	1415:1420	arg1	numbers					1422:1428	MAP colony numbers	1411:1428	MAP colony numbers	1411:1428	The new medium could improve MAP culture in future by reducing incubation times and increasing MAP colony numbers.					
35261128	9	49	theme	7H9	1042:1044	arg1	broth					1046:1050	Middlebrook 7H9 broth	1030:1050	Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1030:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	10	50	theme	incubation	1379:1388	arg1	times					1390:1394	incubation times	1379:1394	incubation times	1379:1394	The new medium could improve MAP culture in future by reducing incubation times and increasing MAP colony numbers.					
35261128	0	51	theme	culture	43:49	arg1	medium					51:56	a solid culture medium	35:56	a solid culture medium	35:56	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	6	52	theme	solid	789:793	arg1	medium					803:808	a new solid culture medium	783:808	a new solid culture medium	783:808	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	53	theme	MAP	1303:1305	arg1	culture					1307:1313	MAP culture	1303:1313	MAP culture	1303:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	1	54	theme	factorial	112:120	arg1	design					122:127	factorial design	112:127	factorial design	112:127	paratuberculosis using factorial design and response surface methodology.					
35261128	0	55	theme	solid	37:41	arg1	medium					51:56	a solid culture medium	35:56	a solid culture medium	35:56	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	9	56	theme	first	1218:1222	arg1	This					1206:1209	This	1206:1209	This	1206:1209	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	56	theme	first	1218:1222	arg1	study					1224:1228	the first study	1214:1228	the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1214:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	57	dep	STUDY	1200:1204	arg1	This					1206:1209	This	1206:1209	This	1206:1209	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	57	dep	STUDY	1200:1204	arg1	study					1224:1228	the first study	1214:1228	the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1214:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	6	58	theme	culture	795:801	arg1	medium					803:808	a new solid culture medium	783:808	a new solid culture medium	783:808	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	2	59	theme	improved	216:223	arg1	growth					225:230	improved growth	216:230	improved growth of Mycobacterium avium subsp	216:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	6	60	theme	factorial	622:630	arg1	design					632:637	a fractional factorial design	609:637	a fractional factorial design	609:637	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	4	61	theme	MAP	421:423	arg1	growth					425:430	MAP growth	421:430	MAP growth	421:430	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	9	62	theme	%	1077:1077	arg1	casitone					1079:1086	0.019% casitone	1072:1086	0.019% casitone	1072:1086	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	6	63	theme	fractional	611:620	arg1	design					632:637	a fractional factorial design	609:637	a fractional factorial design	609:637	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	2	64	theme	culture	197:203	arg1	medium					205:210	an optimized solid culture medium	178:210	an optimized solid culture medium for improved growth of Mycobacterium avium subsp	178:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	1	65	theme	response	133:140	arg1	methodology					150:160	response surface methodology	133:160	response surface methodology	133:160	paratuberculosis using factorial design and response surface methodology.					
35261128	10	66	theme	new	1320:1322	arg1	medium					1324:1329	The new medium	1316:1329	The new medium	1316:1329	The new medium could improve MAP culture in future by reducing incubation times and increasing MAP colony numbers.					
35261128	2	67	theme	solid	191:195	arg1	medium					205:210	an optimized solid culture medium	178:210	an optimized solid culture medium for improved growth of Mycobacterium avium subsp	178:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	2	68	theme	subsp	255:259	arg1	growth					225:230	improved growth	216:230	improved growth of Mycobacterium avium subsp	216:259	AIM To develop an optimized solid culture medium for improved growth of Mycobacterium avium subsp.					
35261128	4	69	theme	medium	312:317	arg1	factors					333:339	factors	333:339	factors	333:339	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	4	69	theme	medium	312:317	arg1	constituents					319:330	Seven medium constituents	306:330	METHODS AND RESULTS Seven medium constituents (factors)	286:340	METHODS AND RESULTS Seven medium constituents (factors) were assessed at various concentrations for their ability to positively affect MAP growth.					
35261128	1	70	theme	surface	142:148	arg1	methodology					150:160	response surface methodology	133:160	response surface methodology	133:160	paratuberculosis using factorial design and response surface methodology.					
35261128	7	71	theme	optimized	861:869	arg1	2 weeks					884:890	the optimized solid medium 2 weeks	857:890	the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM)	857:939	MAP growth became visible on streak plates of the optimized solid medium 2 weeks earlier than on Herrold's egg yolk medium (HEYM).					
35261128	0	72	theme	medium	51:56	arg1	composition					20:30	the composition	16:30	the composition of a solid culture medium	16:56	Optimization of the composition of a solid culture medium for Mycobacterium avium subsp.					
35261128	9	73	theme	ADC	1134:1136	arg1	STUDY					1200:1204	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture	1196:1313	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	9	73	theme	ADC	1134:1136	arg1	%					1132:1132	10% ADC	1130:1136	10% ADC	1130:1136	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35261128	10	74	theme	MAP	1411:1413	arg1	numbers					1422:1428	MAP colony numbers	1411:1428	MAP colony numbers	1411:1428	The new medium could improve MAP culture in future by reducing incubation times and increasing MAP colony numbers.					
35261128	6	75	theme	central	680:686	arg1	design					698:703	central composite design	680:703	central composite design	680:703	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	76	used	used	710:713	arg2	RSM					675:677	RSM	675:677	RSM	675:677	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	76	used	used	710:713	arg2	design					632:637	a fractional factorial design	609:637	a fractional factorial design	609:637	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	76	used	used	710:713	arg2	methodology					662:672	a response surface methodology	643:672	a response surface methodology (RSM)	643:678	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	6	77	theme	factors	600:606	arg1	screening					576:584	an initial screening	565:584	an initial screening of individual factors	565:606	After an initial screening of individual factors, a fractional factorial design and a response surface methodology (RSM) central composite design were used to assess the effects of multiple factors simultaneously and design a new solid culture medium.					
35261128	9	78	theme	RSM	1240:1242	arg1	approach					1244:1251	an RSM approach	1237:1251	an RSM approach	1237:1251	It consisted of Middlebrook 7H9 broth with 1.0% Tween 80, 0.019% casitone, 1.4% bacteriological agar, 10% egg yolk, 10% ADC and 1.65 μg ml-1 Mycobactin J. SIGNIFICANCE AND IMPACT OF THE STUDY This is the first study to use an RSM approach to optimize the composition of a solid medium for MAP culture.					
35191591	0	0	theme	wound	94:98	arg1	healing					100:106	wound healing	94:106	wound healing	94:106	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	8	1	theme	vascular	1083:1090	arg1	factor					1111:1116	vascular endothelial growth factor	1083:1116	vascular endothelial growth factor A	1083:1118	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	9	2	theme	GQDs-BC	1246:1252	arg1	composites					1263:1272	GQDs-BC hydrogel composites	1246:1272	GQDs-BC hydrogel composites	1246:1272	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	1	3	theme	intense	177:183	arg1	research					185:192	intense research	177:192	intense research of new wound healing agents	177:220	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	10	4	theme	new	1406:1408	arg1	dressings					1456:1464	potential wound dressings	1440:1464	potential wound dressings	1440:1464	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	10	4	theme	new	1406:1408	arg1	hydrogels					1427:1435	new designed GQDs-BC hydrogels	1406:1435	new designed GQDs-BC hydrogels	1406:1435	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	8	5	theme	matrix	1121:1126	arg1	metallopeptidase					1128:1143	matrix metallopeptidase 9	1121:1145	matrix metallopeptidase 9	1121:1145	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	5	6	theme	new	571:573	arg1	hydrogels					594:602	new designed composite hydrogels	571:602	new designed composite hydrogels	571:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	9	7	theme	good	1286:1289	arg1	absorption					1303:1312	very good wound fluid absorption	1281:1312	very good wound fluid absorption	1281:1312	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	8	8	from	expression	1166:1175	arg1	fibroblast					1180:1189	fibroblast	1180:1189	fibroblast	1180:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	9	9	theme	wound	1291:1295	arg1	absorption					1303:1312	very good wound fluid absorption	1281:1312	very good wound fluid absorption	1281:1312	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	8	10	theme	growth	1104:1109	arg1	factor					1111:1116	vascular endothelial growth factor	1083:1116	vascular endothelial growth factor A	1083:1118	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	5	11	theme	designed	575:582	arg1	hydrogels					594:602	new designed composite hydrogels	571:602	new designed composite hydrogels	571:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	7	12	theme	GQDs-BC	972:978	arg1	application					990:1000	the GQDs-BC hydrogels application	968:1000	the GQDs-BC hydrogels application	968:1000	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	8	13	theme	endothelial	1092:1102	arg1	factor					1111:1116	vascular endothelial growth factor	1083:1116	vascular endothelial growth factor A	1083:1118	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	5	14	theme	composite	584:592	arg1	hydrogels					594:602	new designed composite hydrogels	571:602	new designed composite hydrogels	571:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	7	15	theme	healing	895:901	arg1	analysis					903:910	The in vitro healing analysis	882:910	The in vitro healing analysis	882:910	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	3	16	theme	bacterial	350:358	arg1	cellulose					360:368	bacterial cellulose	350:368	bacterial cellulose (BC)	350:373	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	3	16	theme	bacterial	350:358	arg1	BC					371:372	BC	371:372	BC	371:372	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	10	17	theme	obtained	1381:1388	arg1	results					1390:1396	All obtained results	1377:1396	All obtained results	1377:1396	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	8	18	theme	A	1118:1118	arg1	expression					1166:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression	1048:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast	1048:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	7	19	dep	in	886:887	arg1	vitro					889:893	vitro	889:893	vitro	889:893	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	2	20	theme	good	295:298	arg1	moisture					300:307	good moisture	295:307	good moisture	295:307	Novel wound dressings should be designed to provide wound disinfection, good moisture, and fast epithelization.					
35191591	7	21	theme	human	944:948	arg1	fibroblasts					950:960	human fibroblasts	944:960	human fibroblasts	944:960	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	3	22	theme	quantum	405:411	arg1	GQDs					419:422	GQDs	419:422	GQDs	419:422	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	3	22	theme	quantum	405:411	arg1	dots					413:416	graphene quantum dots	396:416	graphene quantum dots (GQDs)	396:423	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	8	23	theme	factor	1111:1116	arg1	A					1118:1118	vascular endothelial growth factor A	1083:1118	vascular endothelial growth factor A	1083:1118	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	8	24	theme	nitric	1060:1065	arg1	synthase					1073:1080	endothelial nitric oxide synthase	1048:1080	endothelial nitric oxide synthase	1048:1080	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	7	25	theme	in	886:887	arg1	analysis					903:910	The in vitro healing analysis	882:910	The in vitro healing analysis	882:910	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	1	26	theme	new	197:199	arg1	agents					215:220	new wound healing agents	197:220	new wound healing agents	197:220	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	0	27	theme	composite	14:22	arg1	hydrogels					24:32	Antibacterial composite hydrogels	0:32	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose	0:81	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	10	28	theme	wound	1450:1454	arg1	dressings					1456:1464	potential wound dressings	1440:1464	potential wound dressings	1440:1464	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	10	28	theme	wound	1450:1454	arg1	hydrogels					1427:1435	new designed GQDs-BC hydrogels	1406:1435	new designed GQDs-BC hydrogels	1406:1435	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	8	29	theme	synthase	1073:1080	arg1	expression					1166:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression	1048:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast	1048:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	8	30	theme	endothelial	1048:1058	arg1	synthase					1073:1080	endothelial nitric oxide synthase	1048:1080	endothelial nitric oxide synthase	1048:1080	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	6	31	theme	significant	677:687	arg1	inhibition					689:698	significant inhibition	677:698	significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae	677:757	Novel GQDs-BC hydrogel composites are biocompatible and showed significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae and bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.					
35191591	1	32	theme	wound	201:205	arg1	agents					215:220	new wound healing agents	197:220	new wound healing agents	197:220	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	0	33	theme	Antibacterial	0:12	arg1	hydrogels					24:32	Antibacterial composite hydrogels	0:32	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose	0:81	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	9	34	theme	dressing	1356:1363	arg1	properties					1365:1374	good dressing properties	1351:1374	good dressing properties	1351:1374	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	5	35	theme	GQDs	561:564	arg1	%					611:611	13%	609:611	13%	609:611	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	5	35	theme	GQDs	561:564	arg1	release					550:556	The actual release	539:556	The actual release of GQDs from new designed composite hydrogels	539:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	10	36	theme	designed	1410:1417	arg1	dressings					1456:1464	potential wound dressings	1440:1464	potential wound dressings	1440:1464	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	10	36	theme	designed	1410:1417	arg1	hydrogels					1427:1435	new designed GQDs-BC hydrogels	1406:1435	new designed GQDs-BC hydrogels	1406:1435	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	1	37	theme	healing	207:213	arg1	agents					215:220	new wound healing agents	197:220	new wound healing agents	197:220	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	10	38	theme	potential	1440:1448	arg1	dressings					1456:1464	potential wound dressings	1440:1464	potential wound dressings	1440:1464	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	10	38	theme	potential	1440:1448	arg1	hydrogels					1427:1435	new designed GQDs-BC hydrogels	1406:1435	new designed GQDs-BC hydrogels	1406:1435	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	4	39	theme	GQDs	533:536	arg1	%					528:528	approximately 11.7 wt%	507:528	approximately 11.7 wt% of GQDs	507:536	The BC was successfully loaded with approximately 11.7 wt% of GQDs.					
35191591	4	39	theme	GQDs	533:536	arg1	GQDs					533:536	GQDs	533:536	GQDs	533:536	The BC was successfully loaded with approximately 11.7 wt% of GQDs.					
35191591	7	40	theme	hydrogels	980:988	arg1	application					990:1000	the GQDs-BC hydrogels application	968:1000	the GQDs-BC hydrogels application	968:1000	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	2	41	theme	fast	314:317	arg1	epithelization					319:332	fast epithelization	314:332	fast epithelization	314:332	Novel wound dressings should be designed to provide wound disinfection, good moisture, and fast epithelization.					
35191591	9	42	theme	hydrogel	1254:1261	arg1	composites					1263:1272	GQDs-BC hydrogel composites	1246:1272	GQDs-BC hydrogel composites	1246:1272	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	1	43	theme	agents	215:220	arg1	research					185:192	intense research	177:192	intense research of new wound healing agents	177:220	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	9	44	theme	fluid	1297:1301	arg1	absorption					1303:1312	very good wound fluid absorption	1281:1312	very good wound fluid absorption	1281:1312	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	8	45	theme	metallopeptidase	1128:1143	arg1	expression					1166:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression	1048:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast	1048:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	1	46	theme	increased	113:121	arg1	resistance					134:143	The increased antibiotic resistance	109:143	The increased antibiotic resistance of pathogenic bacteria	109:166	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	3	47	theme	healing	452:458	arg1	treatment					460:468	wound healing treatment	446:468	wound healing treatment	446:468	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	0	48	theme	quantum	46:52	arg1	dots					54:57	graphene quantum dots	37:57	graphene quantum dots	37:57	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	9	49	theme	water	1318:1322	arg1	retention					1324:1332	water retention	1318:1332	water retention	1318:1332	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	6	50	theme	Novel	614:618	arg1	composites					637:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites are biocompatible and showed significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae and bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.					
35191591	0	51	theme	graphene	37:44	arg1	dots					54:57	graphene quantum dots	37:57	graphene quantum dots	37:57	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	7	52	theme	fibroblasts	950:960	arg1	migration					931:939	significant migration	919:939	significant migration of human fibroblasts	919:960	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	3	53	from	use	439:441	arg1	treatment					460:468	wound healing treatment	446:468	wound healing treatment	446:468	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	3	54	theme	graphene	396:403	arg1	GQDs					419:422	GQDs	419:422	GQDs	419:422	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	3	54	theme	graphene	396:403	arg1	dots					413:416	graphene quantum dots	396:416	graphene quantum dots (GQDs)	396:423	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	8	55	theme	gene	1161:1164	arg1	expression					1166:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression	1048:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast	1048:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	1	56	theme	antibiotic	123:132	arg1	resistance					134:143	The increased antibiotic resistance	109:143	The increased antibiotic resistance of pathogenic bacteria	109:166	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	0	57	theme	dots	54:57	arg1	hydrogels					24:32	Antibacterial composite hydrogels	0:32	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose	0:81	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	8	58	theme	Vimentin	1152:1159	arg1	expression					1166:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression	1048:1175	endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast	1048:1189	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	2	59	theme	wound	229:233	arg1	dressings					235:243	Novel wound dressings	223:243	Novel wound dressings	223:243	Novel wound dressings should be designed to provide wound disinfection, good moisture, and fast epithelization.					
35191591	6	60	theme	bactericidal	763:774	arg1	effect					776:781	bactericidal effect	763:781	bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa	763:879	Novel GQDs-BC hydrogel composites are biocompatible and showed significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae and bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.					
35191591	8	61	theme	oxide	1067:1071	arg1	synthase					1073:1080	endothelial nitric oxide synthase	1048:1080	endothelial nitric oxide synthase	1048:1080	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	2	62	theme	Novel	223:227	arg1	dressings					235:243	Novel wound dressings	223:243	Novel wound dressings	223:243	Novel wound dressings should be designed to provide wound disinfection, good moisture, and fast epithelization.					
35191591	5	63	theme	actual	543:548	arg1	%					611:611	13%	609:611	13%	609:611	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	5	63	theme	actual	543:548	arg1	release					550:556	The actual release	539:556	The actual release of GQDs from new designed composite hydrogels	539:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	6	64	theme	hydrogel	628:635	arg1	composites					637:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites are biocompatible and showed significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae and bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.					
35191591	10	65	theme	GQDs-BC	1419:1425	arg1	dressings					1456:1464	potential wound dressings	1440:1464	potential wound dressings	1440:1464	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	10	65	theme	GQDs-BC	1419:1425	arg1	hydrogels					1427:1435	new designed GQDs-BC hydrogels	1406:1435	new designed GQDs-BC hydrogels	1406:1435	All obtained results propose new designed GQDs-BC hydrogels as potential wound dressings.					
35191591	9	66	theme	good	1351:1354	arg1	properties					1365:1374	good dressing properties	1351:1374	good dressing properties	1351:1374	GQDs-BC hydrogel composites showed very good wound fluid absorption and water retention, which satisfies good dressing properties.					
35191591	2	67	theme	wound	275:279	arg1	disinfection					281:292	wound disinfection	275:292	wound disinfection	275:292	Novel wound dressings should be designed to provide wound disinfection, good moisture, and fast epithelization.					
35191591	1	68	theme	pathogenic	148:157	arg1	bacteria					159:166	pathogenic bacteria	148:166	pathogenic bacteria	148:166	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	6	69	theme	GQDs-BC	620:626	arg1	composites					637:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites	614:646	Novel GQDs-BC hydrogel composites are biocompatible and showed significant inhibition towards Staphylococcus aureus and Streptococcus agalactiae and bactericidal effect towards Methicillin-resistant Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.					
35191591	0	70	theme	cellulose	73:81	arg1	hydrogels					24:32	Antibacterial composite hydrogels	0:32	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose	0:81	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	7	71	theme	significant	919:929	arg1	migration					931:939	significant migration	919:939	significant migration of human fibroblasts	919:960	The in vitro healing analysis showed significant migration of human fibroblasts after the GQDs-BC hydrogels application.					
35191591	3	72	theme	wound	446:450	arg1	healing					452:458	wound healing	446:458	wound healing treatment	446:468	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	1	73	theme	bacteria	159:166	arg1	resistance					134:143	The increased antibiotic resistance	109:143	The increased antibiotic resistance of pathogenic bacteria	109:166	The increased antibiotic resistance of pathogenic bacteria requires intense research of new wound healing agents.					
35191591	3	74	theme	potential	429:437	arg1	use					439:441	potential use	429:441	potential use in wound healing treatment	429:468	In this study, bacterial cellulose (BC) was impregnated with graphene quantum dots (GQDs) for potential use in wound healing treatment.					
35191591	0	75	theme	bacterial	63:71	arg1	cellulose					73:81	bacterial cellulose	63:81	bacterial cellulose	63:81	Antibacterial composite hydrogels of graphene quantum dots and bacterial cellulose accelerate wound healing.					
35191591	8	76	theme	72 h	1022:1025	arg1	exposure					1027:1034	72 h exposure	1022:1034	72 h exposure to GQDs-BC	1022:1045	Furthermore, after 72 h exposure to GQDs-BC, endothelial nitric oxide synthase, vascular endothelial growth factor A, matrix metallopeptidase 9, and Vimentin gene expression in fibroblast were significantly upregulated promoting angiogenesis.					
35191591	5	77	from	hydrogels	594:602	arg1	%					611:611	13%	609:611	13%	609:611	The actual release of GQDs from new designed composite hydrogels were 13%.					
35191591	5	77	from	hydrogels	594:602	arg1	release					550:556	The actual release	539:556	The actual release of GQDs from new designed composite hydrogels	539:602	The actual release of GQDs from new designed composite hydrogels were 13%.					
36963538	0	0	theme	deacetylation	83:95	arg1	degrees					97:103	deacetylation degrees	83:103	deacetylation degrees	83:103	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	4	1	dep	maximum	825:831	arg1	148.88 g					845:852	148.88 g	845:852	148.88 g	845:852	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	4	1	dep	maximum	825:831	arg1	244.15					834:839	244.15	834:839	244.15	834:839	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	6	2	theme	composite	1191:1199	arg1	gels					1201:1204	the composite gels	1187:1204	the composite gels	1187:1204	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	8	3	theme	KGM	1411:1413	arg1	DDs					1404:1406	the DDs	1400:1406	the DDs of KGM	1400:1413	Overall, the gelation characteristics of the WPI-KGM system can be regulated by controlling the DDs of KGM.					
36963538	1	4	theme	isolate	227:233	arg1	properties					200:209	the gel properties	192:209	the gel properties of whey protein isolate (WPI)	192:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	4	5	theme	%	889:889	arg1	DDs					876:878	the DDs	872:878	the DDs of 53.85 %	872:889	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	3	6	theme	acetyl	628:633	arg1	groups					635:640	acetyl groups	628:640	acetyl groups	628:640	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	4	7	theme	DDs	804:806	arg1	enhancement					789:799	the enhancement	785:799	the enhancement of DDs	785:806	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	1	8	theme	different	151:159	arg1	DDs					184:186	DDs	184:186	DDs	184:186	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	8	theme	different	151:159	arg1	degrees					175:181	different deacetylation degrees	151:181	different deacetylation degrees (DDs)	151:187	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	3	9	theme	groups	635:640	arg1	removal					617:623	the removal	613:623	the removal of acetyl groups	613:640	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	2	10	from	DDs	296:298	arg1	range					307:311	the range	303:311	the range of 0-53.85 %	303:324	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	6	11	theme	disulfide	1098:1106	arg1	bond					1108:1111	disulfide bond	1098:1111	disulfide bond	1098:1111	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	5	12	theme	rheological	896:906	arg1	analysis					908:915	The rheological analysis	892:915	The rheological analysis	892:915	The rheological analysis indicated that rigid structured WPI-KGM gels could be formed when incorporated with moderately deacetylated KGM.					
36963538	0	13	theme	degrees	97:103	arg1	Effects					72:78	Effects	72:78	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.	0:104	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	5	14	theme	deacetylated	1012:1023	arg1	KGM					1025:1027	moderately deacetylated KGM	1001:1027	moderately deacetylated KGM	1001:1027	The rheological analysis indicated that rigid structured WPI-KGM gels could be formed when incorporated with moderately deacetylated KGM.					
36963538	6	15	theme	deacetylated	1034:1045	arg1	KGM					1047:1049	The deacetylated KGM	1030:1049	The deacetylated KGM (DDs = 53.85 %)	1030:1065	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	6	15	theme	deacetylated	1034:1045	arg1	%					1064:1064	DDs = 53.85 %	1052:1064	DDs = 53.85 %	1052:1064	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	2	16	theme	macroscopic	461:471	arg1	precipitation					473:485	macroscopic precipitation	461:485	macroscopic precipitation	461:485	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	3	17	theme	composite	671:679	arg1	gels					681:684	the composite gels	667:684	the composite gels	667:684	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	1	18	with	glucomannan	128:138	arg1	DDs					184:186	DDs	184:186	DDs	184:186	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	18	with	glucomannan	128:138	arg1	degrees					175:181	different deacetylation degrees	151:181	different deacetylation degrees (DDs)	151:187	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	19	theme	deacetylation	161:173	arg1	DDs					184:186	DDs	184:186	DDs	184:186	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	19	theme	deacetylation	161:173	arg1	degrees					175:181	different deacetylation degrees	151:181	different deacetylation degrees (DDs)	151:187	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	2	20	theme	deacetylated	412:423	arg1	%					451:451	DDs = 63.46 or 71.63 %	430:451	DDs = 63.46 or 71.63 %	430:451	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	2	20	theme	deacetylated	412:423	arg1	KGM					425:427	excessive deacetylated KGM	402:427	excessive deacetylated KGM (DDs = 63.46 or 71.63 %)	402:452	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	6	21	theme	compact	1158:1164	arg1	structure					1174:1182	a more compact network structure	1151:1182	a more compact network structure of the composite gels	1151:1204	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	6	22	theme	hydrogen	1080:1087	arg1	bond					1089:1092	the hydrogen bond	1076:1092	the hydrogen bond	1076:1092	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	8	23	theme	system	1361:1366	arg1	characteristics					1330:1344	the gelation characteristics	1317:1344	the gelation characteristics of the WPI-KGM system	1317:1366	Overall, the gelation characteristics of the WPI-KGM system can be regulated by controlling the DDs of KGM.					
36963538	4	24	theme	composite	721:729	arg1	gel					731:733	the composite gel	717:733	the composite gel	717:733	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	2	25	theme	excessive	402:410	arg1	%					451:451	DDs = 63.46 or 71.63 %	430:451	DDs = 63.46 or 71.63 %	430:451	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	2	25	theme	excessive	402:410	arg1	KGM					425:427	excessive deacetylated KGM	402:427	excessive deacetylated KGM (DDs = 63.46 or 71.63 %)	402:452	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	3	26	theme	water	526:530	arg1	capacity					540:547	The water holding capacity	522:547	The water holding capacity of WPI-KGM gels	522:563	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	7	27	theme	deacetylated	1217:1228	arg1	particles					1234:1242	deacetylated KGM particles	1217:1242	deacetylated KGM particles	1217:1242	Moreover, deacetylated KGM particles might also reinforce the gel strength by the "filling effects".					
36963538	6	28	theme	network	1166:1172	arg1	structure					1174:1182	a more compact network structure	1151:1182	a more compact network structure of the composite gels	1151:1204	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	3	29	theme	holding	532:538	arg1	capacity					540:547	The water holding capacity	522:547	The water holding capacity of WPI-KGM gels	522:563	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	7	30	theme	gel	1269:1271	arg1	strength					1273:1280	the gel strength	1265:1280	the gel strength	1265:1280	Moreover, deacetylated KGM particles might also reinforce the gel strength by the "filling effects".					
36963538	7	31	theme	KGM	1230:1232	arg1	particles					1234:1242	deacetylated KGM particles	1217:1242	deacetylated KGM particles	1217:1242	Moreover, deacetylated KGM particles might also reinforce the gel strength by the "filling effects".					
36963538	0	32	theme	protein	19:25	arg1	gels					66:69	whey protein isolation/konjac glucomannan composite gels	14:69	whey protein isolation/konjac glucomannan composite gels	14:69	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	2	33	theme	deacetylated	278:289	arg1	KGM					291:293	The appropriately deacetylated KGM	260:293	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %)	260:325	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	2	34	theme	compound	381:388	arg1	gels					390:393	relatively uniform compound gels	362:393	relatively uniform compound gels	362:393	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	0	35	theme	whey	14:17	arg1	gels					66:69	whey protein isolation/konjac glucomannan composite gels	14:69	whey protein isolation/konjac glucomannan composite gels	14:69	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	3	36	theme	gels	681:684	arg1	whiteness					654:662	the whiteness	650:662	the whiteness of the composite gels	650:684	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	2	37	theme	WPI-KGM	506:512	arg1	system					514:519	WPI-KGM system	506:519	WPI-KGM system	506:519	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	3	38	theme	DDs	604:606	arg1	increase					592:599	the gradual increase	580:599	the gradual increase of DDs	580:606	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	2	39	theme	uniform	373:379	arg1	gels					390:393	relatively uniform compound gels	362:393	relatively uniform compound gels	362:393	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	0	40	theme	glucomannan	44:54	arg1	gels					66:69	whey protein isolation/konjac glucomannan composite gels	14:69	whey protein isolation/konjac glucomannan composite gels	14:69	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	3	41	theme	WPI-KGM	552:558	arg1	gels					560:563	WPI-KGM gels	552:563	WPI-KGM gels	552:563	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	0	42	theme	isolation/konjac	27:42	arg1	gels					66:69	whey protein isolation/konjac glucomannan composite gels	14:69	whey protein isolation/konjac glucomannan composite gels	14:69	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	7	43	theme	filling	1290:1296	arg1	effects					1298:1304	the "filling effects	1285:1304	the "filling effects"	1285:1305	Moreover, deacetylated KGM particles might also reinforce the gel strength by the "filling effects".					
36963538	8	44	theme	WPI-KGM	1353:1359	arg1	system					1361:1366	the WPI-KGM system	1349:1366	the WPI-KGM system	1349:1366	Overall, the gelation characteristics of the WPI-KGM system can be regulated by controlling the DDs of KGM.					
36963538	3	45	theme	gels	560:563	arg1	capacity					540:547	The water holding capacity	522:547	The water holding capacity of WPI-KGM gels	522:563	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	1	46	theme	gel	196:198	arg1	properties					200:209	the gel properties	192:209	the gel properties of whey protein isolate (WPI)	192:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	0	47	theme	gels	66:69	arg1	Properties					0:9	Properties	0:9	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.	0:104	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	5	48	theme	structured	938:947	arg1	gels					957:960	rigid structured WPI-KGM gels	932:960	rigid structured WPI-KGM gels	932:960	The rheological analysis indicated that rigid structured WPI-KGM gels could be formed when incorporated with moderately deacetylated KGM.					
36963538	4	49	dep	hardness	691:698	arg1	The					687:689	The	687:689	The	687:689	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	0	50	theme	composite	56:64	arg1	gels					66:69	whey protein isolation/konjac glucomannan composite gels	14:69	whey protein isolation/konjac glucomannan composite gels	14:69	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	5	51	theme	WPI-KGM	949:955	arg1	gels					957:960	rigid structured WPI-KGM gels	932:960	rigid structured WPI-KGM gels	932:960	The rheological analysis indicated that rigid structured WPI-KGM gels could be formed when incorporated with moderately deacetylated KGM.					
36963538	1	52	theme	konjac	121:126	arg1	glucomannan					128:138	konjac glucomannan	121:138	konjac glucomannan (KGM) with different deacetylation degrees (DDs)	121:187	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	52	theme	konjac	121:126	arg1	KGM					141:143	KGM	141:143	KGM	141:143	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	6	53	theme	mixed	1124:1128	arg1	system					1130:1135	the mixed system	1120:1135	the mixed system	1120:1135	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	4	54	theme	gel	731:733	arg1	chewiness					704:712	chewiness	704:712	chewiness	704:712	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	4	54	theme	gel	731:733	arg1	hardness					691:698	hardness	691:698	hardness	691:698	The hardness and chewiness of the composite gel tended to increase and subsequently decrease with the enhancement of DDs, and reached the maximum (244.15 and 148.88 g, respectively) at the DDs of 53.85 %.					
36963538	5	55	theme	rigid	932:936	arg1	gels					957:960	rigid structured WPI-KGM gels	932:960	rigid structured WPI-KGM gels	932:960	The rheological analysis indicated that rigid structured WPI-KGM gels could be formed when incorporated with moderately deacetylated KGM.					
36963538	1	56	theme	glucomannan	128:138	arg1	effects					110:116	The effects	106:116	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI)	106:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	57	from	effects	110:116	arg1	properties					200:209	the gel properties	192:209	the gel properties of whey protein isolate (WPI)	192:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	6	58	theme	gels	1201:1204	arg1	structure					1174:1182	a more compact network structure	1151:1182	a more compact network structure of the composite gels	1151:1204	The deacetylated KGM (DDs = 53.85 %) enhanced the hydrogen bond and disulfide bond within the mixed system, resulting in a more compact network structure of the composite gels.					
36963538	3	59	theme	gradual	584:590	arg1	increase					592:599	the gradual increase	580:599	the gradual increase of DDs	580:606	The water holding capacity of WPI-KGM gels decreased with the gradual increase of DDs, and the removal of acetyl groups reduced the whiteness of the composite gels.					
36963538	2	60	dep	KGM	291:293	arg1	DDs					296:298	DDs	296:298	DDs in the range of 0-53.85 %	296:324	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	8	61	theme	gelation	1321:1328	arg1	characteristics					1330:1344	the gelation characteristics	1317:1344	the gelation characteristics of the WPI-KGM system	1317:1366	Overall, the gelation characteristics of the WPI-KGM system can be regulated by controlling the DDs of KGM.					
36963538	1	62	theme	whey	214:217	arg1	WPI					236:238	WPI	236:238	WPI	236:238	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	62	theme	whey	214:217	arg1	isolate					227:233	whey protein isolate	214:233	whey protein isolate (WPI)	214:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	0	63	dep	Properties	0:9	arg1	Effects					72:78	Effects	72:78	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.	0:104	Properties of whey protein isolation/konjac glucomannan composite gels: Effects of deacetylation degrees.					
36963538	2	64	theme	%	324:324	arg1	range					307:311	the range	303:311	the range of 0-53.85 %	303:324	The appropriately deacetylated KGM (DDs in the range of 0-53.85 %) incorporated within WPI and formed relatively uniform compound gels, while excessive deacetylated KGM (DDs = 63.46 or 71.63 %) caused macroscopic precipitation and aggregation in WPI-KGM system.					
36963538	1	65	theme	protein	219:225	arg1	WPI					236:238	WPI	236:238	WPI	236:238	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36963538	1	65	theme	protein	219:225	arg1	isolate					227:233	whey protein isolate	214:233	whey protein isolate (WPI)	214:239	The effects of konjac glucomannan (KGM) with different deacetylation degrees (DDs) on the gel properties of whey protein isolate (WPI) were investigated.					
36200766	10	0	with	strains	1647:1653	arg1	phenotype					1669:1677	a xylan+ phenotype	1660:1677	a xylan+ phenotype	1660:1677	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	15	1	theme	other	2414:2418	arg1	fibers					2428:2433	other dietary fibers	2414:2433	other dietary fibers	2414:2433	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	7	2	theme	GH10	1149:1152	arg1	enzyme					1181:1186	a key enzyme	1175:1186	a key enzyme for primary degradation of xylan	1175:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	2	theme	GH10	1149:1152	arg1	xylanase					1165:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	11	3	contain	have	1787:1790	arg1	strains					1775:1781	xylan+ B. pseudocatenulatum strains	1747:1781	xylan+ B. pseudocatenulatum strains	1747:1781	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	11	3	contain	have	1787:1790	arg2	advantage					1806:1814	a competitive advantage	1792:1814	a competitive advantage	1792:1814	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	5	4	theme	longer-chain	692:703	arg1	substrates					719:728	longer-chain XOS and xylan substrates	692:728	longer-chain XOS and xylan substrates	692:728	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	6	5	theme	B.	837:838	arg1	ED02					858:861	B. pseudocatenulatum ED02	837:861	B. pseudocatenulatum ED02	837:861	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	9	6	theme	XOS	1458:1460	arg1	fragments					1462:1470	XOS fragments	1458:1470	XOS fragments	1458:1470	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	6	7	theme	polymerization	910:923	arg1	degree					900:905	a high degree	893:905	a high degree of polymerization (DP) and straight-chain xylan	893:953	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	8	8	theme	xylanase	1255:1262	arg1	presence					1226:1233	The presence	1222:1233	The presence of an extracellular xylanase	1222:1262	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	6	9	from	growth	874:879	arg1	XOS					884:886	XOS	884:886	XOS	884:886	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	7	10	theme	strains	1114:1120	arg1	genomes					1071:1077	only the genomes	1062:1077	only the genomes of these xylan-fermenting (xylan+) strains	1062:1120	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	2	11	used	utilized	263:270	arg2	they					254:257	they	254:257	they	254:257	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	5	12	contain	have	640:643	arg2	systems					655:661	metabolic systems	645:661	metabolic systems for XOS	645:669	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	5	12	contain	have	640:643	arg1	species					632:638	several Bifidobacterium species	608:638	several Bifidobacterium species	608:638	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	10	13	theme	in	1604:1605	arg1	fermentations					1619:1631	in vitro fecal fermentations	1604:1631	in vitro fecal fermentations	1604:1631	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	11	14	theme	complex	1823:1829	arg1	environment					1831:1841	the complex environment	1819:1841	the complex environment of the gastrointestinal tract	1819:1871	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	10	15	dep	in	1604:1605	arg1	vitro					1607:1611	vitro	1607:1611	vitro	1607:1611	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	12	16	theme	dietary	2021:2027	arg1	fiber					2029:2033	dietary fiber	2021:2033	dietary fiber	2021:2033	IMPORTANCE The beneficial health effects of dietary fiber are now well established.					
36200766	16	17	theme	Bifidobacterium	2632:2646	arg1	pseudocatenulatum					2648:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	7	18	theme	xylan-fermenting	1088:1103	arg1	strains					1114:1120	these xylan-fermenting (xylan+) strains	1082:1120	these xylan-fermenting (xylan+) strains	1082:1120	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	11	19	dep	B.	1754:1755	arg1	pseudocatenulatum					1757:1773	pseudocatenulatum	1757:1773	pseudocatenulatum	1757:1773	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	2	20	theme	gut	290:292	arg1	microbiota					294:303	the gut microbiota	286:303	the gut microbiota	286:303	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	6	21	theme	primary	969:975	arg1	phenotype					986:994	a primary degrader phenotype	967:994	a primary degrader phenotype that is rare in Bifidobacterium	967:1026	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	6	21	theme	primary	969:975	arg1	rare					1004:1007	rare	1004:1007	rare	1004:1007	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	14	22	theme	gap	2186:2188	arg1	"					2189:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	11	23	theme	gastrointestinal	1850:1865	arg1	tract					1867:1871	the gastrointestinal tract	1846:1871	the gastrointestinal tract	1846:1871	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	7	24	theme	key	1177:1179	arg1	enzyme					1181:1186	a key enzyme	1175:1186	a key enzyme for primary degradation of xylan	1175:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	24	theme	key	1177:1179	arg1	xylanase					1165:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	15	25	theme	microbiome	2496:2505	arg1	function					2507:2514	gut microbiome function	2492:2514	gut microbiome function	2492:2514	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	9	26	theme	6	1490:1490	arg1	DP					1479:1480	a DP	1477:1480	a DP of 2 to 6	1477:1490	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	12	27	theme	beneficial	1992:2001	arg1	effects					2010:2016	The beneficial health effects	1988:2016	IMPORTANCE The beneficial health effects of dietary fiber	1977:2033	IMPORTANCE The beneficial health effects of dietary fiber are now well established.					
36200766	8	28	theme	hydrolysis	1305:1314	arg1	products					1316:1323	xylan hydrolysis products	1299:1323	xylan hydrolysis products	1299:1323	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	10	29	theme	fecal	1613:1617	arg1	fermentations					1619:1631	in vitro fecal fermentations	1604:1631	in vitro fecal fermentations	1604:1631	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	1	30	theme	xylose-based	125:136	arg1	polysaccharides					138:152	xylose-based polysaccharides	125:152	xylose-based polysaccharides	125:152	Xylans, a family of xylose-based polysaccharides, are dietary fibers resistant to digestion.					
36200766	6	31	theme	xylan	949:953	arg1	degree					900:905	a high degree	893:905	a high degree of polymerization (DP) and straight-chain xylan	893:953	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	16	32	link	human-derived	2618:2630	arg1	pseudocatenulatum					2648:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	15	33	theme	gut	2492:2494	arg1	function					2507:2514	gut microbiome function	2492:2514	gut microbiome function	2492:2514	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	15	34	theme	keystone	2357:2364	arg1	species					2376:2382	keystone bacterial species	2357:2382	keystone bacterial species in the gut	2357:2393	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	9	35	theme	thin-layer	1507:1516	arg1	TLC					1534:1536	TLC	1534:1536	TLC	1534:1536	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	9	35	theme	thin-layer	1507:1516	arg1	chromatography					1518:1531	thin-layer chromatography	1507:1531	thin-layer chromatography (TLC)	1507:1537	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	16	36	theme	genetic	2568:2574	arg1	evidence					2576:2583	biochemical and genetic evidence	2552:2583	biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum	2552:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	9	37	located	detected	1396:1403	arg2	activity					1378:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	9	37	located	detected	1396:1403	arg1	strains					1415:1421	xylan+ strains	1408:1421	xylan+ strains	1408:1421	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	11	38	theme	B.	1754:1755	arg1	strains					1775:1781	xylan+ B. pseudocatenulatum strains	1747:1781	xylan+ B. pseudocatenulatum strains	1747:1781	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	1	39	theme	dietary	159:165	arg1	fibers					167:172	dietary fibers	159:172	dietary fibers	159:172	Xylans, a family of xylose-based polysaccharides, are dietary fibers resistant to digestion.					
36200766	15	40	from	species	2376:2382	arg1	gut					2391:2393	the gut	2387:2393	the gut	2387:2393	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	14	41	theme	so-called	2169:2177	arg1	"					2189:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	7	42	contain	contained	1122:1130	arg2	enzyme					1181:1186	a key enzyme	1175:1186	a key enzyme for primary degradation of xylan	1175:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	42	contain	contained	1122:1130	arg2	xylanase					1165:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	42	contain	contained	1122:1130	arg1	genomes					1071:1077	only the genomes	1062:1077	only the genomes of these xylan-fermenting (xylan+) strains	1062:1120	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	11	43	theme	competitive	1794:1804	arg1	advantage					1806:1814	a competitive advantage	1792:1814	a competitive advantage	1792:1814	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	0	44	theme	Carbohydrates	90:102	arg1	Degradation					45:55	Degradation	45:55	Degradation	45:55	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	0	44	theme	Carbohydrates	90:102	arg1	Consumption					61:71	Consumption	61:71	Consumption	61:71	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	13	45	theme	increased	2112:2120	arg1	risks					2122:2126	increased risks	2112:2126	increased risks of metabolic and systemic diseases	2112:2161	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	16	46	theme	xylan	2597:2601	arg1	utilization					2603:2613	primary xylan utilization	2589:2613	primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum	2589:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	0	47	from	Role	0:3	arg1	Degradation					45:55	Degradation	45:55	Degradation	45:55	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	0	47	from	Role	0:3	arg1	Consumption					61:71	Consumption	61:71	Consumption	61:71	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	12	48	dep	IMPORTANCE	1977:1986	arg1	effects					2010:2016	The beneficial health effects	1988:2016	IMPORTANCE The beneficial health effects of dietary fiber	1977:2033	IMPORTANCE The beneficial health effects of dietary fiber are now well established.					
36200766	13	49	theme	low	2071:2073	arg1	consumption					2081:2091	low fiber consumption	2071:2091	low fiber consumption	2071:2091	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	5	50	theme	metabolic	645:653	arg1	systems					655:661	metabolic systems	645:661	metabolic systems for XOS	645:669	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	9	51	theme	high-performance	1543:1558	arg1	HPLC					1583:1586	HPLC	1583:1586	HPLC	1583:1586	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	9	51	theme	high-performance	1543:1558	arg1	chromatography					1567:1580	high-performance liquid chromatography	1543:1580	high-performance liquid chromatography (HPLC)	1543:1587	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	6	52	from	rare	1004:1007	arg1	Bifidobacterium					1012:1026	Bifidobacterium	1012:1026	Bifidobacterium	1012:1026	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	7	53	dep	In	1029:1030	arg1	silico					1032:1037	silico	1032:1037	silico	1032:1037	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	10	54	theme	xylan+	1662:1667	arg1	phenotype					1669:1677	a xylan+ phenotype	1660:1677	a xylan+ phenotype	1660:1677	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	16	55	theme	species	2754:2760	arg1	members					2738:2744	other members	2732:2744	other members of this species	2732:2760	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	6	56	from	Bifidobacterium	1012:1026	arg1	phenotype					986:994	a primary degrader phenotype	967:994	a primary degrader phenotype that is rare in Bifidobacterium	967:1026	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	6	56	from	Bifidobacterium	1012:1026	arg1	rare					1004:1007	rare	1004:1007	rare	1004:1007	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	14	57	theme	disrupted	2273:2281	arg1	microbiota					2296:2305	a disrupted or dysbiotic microbiota	2271:2305	a disrupted or dysbiotic microbiota	2271:2305	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	11	58	theme	primary	1905:1911	arg1	degraders					1913:1921	primary degraders	1905:1921	primary degraders of xylan	1905:1930	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	7	59	theme	primary	1192:1198	arg1	degradation					1200:1210	primary degradation	1192:1210	primary degradation of xylan	1192:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	9	60	theme	xylanolytic	1366:1376	arg1	activity					1378:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	15	61	theme	bacterial	2366:2374	arg1	species					2376:2382	keystone bacterial species	2357:2382	keystone bacterial species in the gut	2357:2393	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	5	62	theme	several	608:614	arg1	species					632:638	several Bifidobacterium species	608:638	several Bifidobacterium species	608:638	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	11	63	theme	enzymatic	1954:1962	arg1	degradation					1964:1974	extracellular enzymatic degradation	1940:1974	extracellular enzymatic degradation	1940:1974	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	0	64	theme	Bifidobacterium	8:22	arg1	pseudocatenulatum					24:40	Bifidobacterium pseudocatenulatum	8:40	Bifidobacterium pseudocatenulatum	8:40	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	6	65	theme	high	895:898	arg1	degree					900:905	a high degree	893:905	a high degree of polymerization (DP) and straight-chain xylan	893:953	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	16	66	theme	cooperative	2685:2695	arg1	utilization					2697:2707	cooperative utilization	2685:2707	cooperative utilization of xylans	2685:2717	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	6	67	theme	pseudocatenulatum	785:801	arg1	strains					758:764	strains	758:764	strains of Bifidobacterium pseudocatenulatum	758:801	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	9	68	theme	xylan+	1408:1413	arg1	strains					1415:1421	xylan+ strains	1408:1421	xylan+ strains	1408:1421	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	4	69	theme	cross-feed	543:552	arg1	consumers					564:572	cross-feed secondary consumers	543:572	cross-feed secondary consumers	543:572	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	4	69	theme	cross-feed	543:552	arg1	Bifidobacterium					585:599	Bifidobacterium	585:599	Bifidobacterium	585:599	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	9	70	with	fragments	1462:1470	arg1	DP					1479:1480	a DP	1477:1480	a DP of 2 to 6	1477:1490	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	11	71	theme	xylan+	1747:1752	arg1	strains					1775:1781	xylan+ B. pseudocatenulatum strains	1747:1781	xylan+ B. pseudocatenulatum strains	1747:1781	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	14	72	theme	microbiome	2248:2257	arg1	composition					2225:2235	the composition	2221:2235	the composition of the gut microbiome	2221:2257	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	6	73	theme	straight-chain	934:947	arg1	xylan					949:953	straight-chain xylan	934:953	straight-chain xylan	934:953	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	16	74	theme	other	2732:2736	arg1	members					2738:2744	other members	2732:2744	other members of this species	2732:2760	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	7	75	theme	extracellular	1135:1147	arg1	enzyme					1181:1186	a key enzyme	1175:1186	a key enzyme for primary degradation of xylan	1175:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	75	theme	extracellular	1135:1147	arg1	xylanase					1165:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	6	76	theme	pseudocatenulatum	840:856	arg1	ED02					858:861	B. pseudocatenulatum ED02	837:861	B. pseudocatenulatum ED02	837:861	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	12	77	theme	fiber	2029:2033	arg1	effects					2010:2016	The beneficial health effects	1988:2016	IMPORTANCE The beneficial health effects of dietary fiber	1977:2033	IMPORTANCE The beneficial health effects of dietary fiber are now well established.					
36200766	9	78	theme	fragments	1462:1470	arg1	production					1444:1453	the production	1440:1453	the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC)	1440:1587	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	8	79	theme	extracellular	1241:1253	arg1	xylanase					1255:1262	an extracellular xylanase	1238:1262	an extracellular xylanase	1238:1262	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	14	80	theme	profound	2202:2209	arg1	impact					2211:2216	a profound impact	2200:2216	a profound impact	2200:2216	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	12	81	theme	health	2003:2008	arg1	effects					2010:2016	The beneficial health effects	1988:2016	IMPORTANCE The beneficial health effects of dietary fiber	1977:2033	IMPORTANCE The beneficial health effects of dietary fiber are now well established.					
36200766	7	82	theme	xylan+	1106:1111	arg1	strains					1114:1120	these xylan-fermenting (xylan+) strains	1082:1120	these xylan-fermenting (xylan+) strains	1082:1120	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	2	83	theme	microbiota	294:303	arg1	members					275:281	members	275:281	members of the gut microbiota	275:303	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	6	84	theme	degrader	977:984	arg1	phenotype					986:994	a primary degrader phenotype	967:994	a primary degrader phenotype that is rare in Bifidobacterium	967:1026	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	6	84	theme	degrader	977:984	arg1	rare					1004:1007	rare	1004:1007	rare	1004:1007	In this study, we isolated strains of Bifidobacterium pseudocatenulatum and observed that some, including B. pseudocatenulatum ED02, displayed growth on XOS with a high degree of polymerization (DP) and straight-chain xylan, suggesting a primary degrader phenotype that is rare in Bifidobacterium.					
36200766	2	85	dep	intestine	229:237	arg1	utilized					263:270	utilized	263:270	are utilized by members of the gut microbiota	259:303	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	14	86	theme	fiber	2180:2184	arg1	"					2189:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	11	87	theme	tract	1867:1871	arg1	environment					1831:1841	the complex environment	1819:1841	the complex environment of the gastrointestinal tract	1819:1871	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	5	88	theme	XOS	705:707	arg1	substrates					719:728	longer-chain XOS and xylan substrates	692:728	longer-chain XOS and xylan substrates	692:728	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	2	89	theme	intact	239:244	arg1	intestine					229:237	the large intestine intact	219:244	the large intestine intact; there, they are utilized by members of the gut microbiota	219:303	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	8	90	theme	xylan	1299:1303	arg1	products					1316:1323	xylan hydrolysis products	1299:1323	xylan hydrolysis products	1299:1323	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	5	91	theme	xylan	713:717	arg1	substrates					719:728	longer-chain XOS and xylan substrates	692:728	longer-chain XOS and xylan substrates	692:728	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	13	92	theme	metabolic	2131:2139	arg1	diseases					2154:2161	metabolic and systemic diseases	2131:2161	metabolic and systemic diseases	2131:2161	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	7	93	theme	In	1029:1030	arg1	analyses					1039:1046	In silico analyses	1029:1046	In silico analyses	1029:1046	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	1	94	theme	polysaccharides	138:152	arg1	Xylans					105:110	Xylans	105:110	Xylans	105:110	Xylans, a family of xylose-based polysaccharides, are dietary fibers resistant to digestion.					
36200766	1	94	theme	polysaccharides	138:152	arg1	family					115:120	a family	113:120	a family of xylose-based polysaccharides	113:152	Xylans, a family of xylose-based polysaccharides, are dietary fibers resistant to digestion.					
36200766	4	95	theme	resulting	439:447	arg1	XOS					471:473	XOS	471:473	XOS	471:473	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	4	95	theme	resulting	439:447	arg1	xylooligosaccharides					449:468	The resulting xylooligosaccharides	435:468	The resulting xylooligosaccharides (XOS)	435:474	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	8	96	theme	products	1316:1323	arg1	appearance					1285:1294	the appearance	1281:1294	the appearance of xylan hydrolysis products in cell-free supernatants	1281:1349	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	0	97	theme	Xylan-Derived	76:88	arg1	Carbohydrates					90:102	Xylan-Derived Carbohydrates	76:102	Xylan-Derived Carbohydrates	76:102	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	13	98	theme	systemic	2145:2152	arg1	diseases					2154:2161	metabolic and systemic diseases	2131:2161	metabolic and systemic diseases	2131:2161	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	8	99	from	appearance	1285:1294	arg1	supernatants					1338:1349	cell-free supernatants	1328:1349	cell-free supernatants	1328:1349	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	16	100	theme	primary	2589:2595	arg1	utilization					2603:2613	primary xylan utilization	2589:2613	primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum	2589:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	8	101	theme	cell-free	1328:1336	arg1	supernatants					1338:1349	cell-free supernatants	1328:1349	cell-free supernatants	1328:1349	The presence of an extracellular xylanase was confirmed by the appearance of xylan hydrolysis products in cell-free supernatants.					
36200766	15	102	theme	dietary	2420:2426	arg1	fibers					2428:2433	other dietary fibers	2414:2433	other dietary fibers	2414:2433	Therefore, understanding the mechanisms by which keystone bacterial species in the gut utilize xylans and other dietary fibers may provide a basis for developing strategies to restore gut microbiome function.					
36200766	4	103	theme	primary	522:528	arg1	degraders					530:538	primary degraders	522:538	primary degraders	522:538	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	4	103	theme	primary	522:528	arg1	Bifidobacterium					585:599	Bifidobacterium	585:599	Bifidobacterium	585:599	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	13	104	theme	diseases	2154:2161	arg1	risks					2122:2126	increased risks	2112:2126	increased risks of metabolic and systemic diseases	2112:2161	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	7	105	theme	xylan	1215:1219	arg1	degradation					1200:1210	primary degradation	1192:1210	primary degradation of xylan	1192:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	16	106	theme	human-derived	2618:2630	arg1	pseudocatenulatum					2648:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	human-derived Bifidobacterium pseudocatenulatum	2618:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	13	107	theme	fiber	2075:2079	arg1	consumption					2081:2091	low fiber consumption	2071:2091	low fiber consumption	2071:2091	Moreover, low fiber consumption is associated with increased risks of metabolic and systemic diseases.					
36200766	9	108	theme	liquid	1560:1565	arg1	HPLC					1583:1586	HPLC	1583:1586	HPLC	1583:1586	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	9	108	theme	liquid	1560:1565	arg1	chromatography					1567:1580	high-performance liquid chromatography	1543:1580	high-performance liquid chromatography (HPLC)	1543:1587	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	3	109	theme	primary	340:346	arg1	degraders					348:356	primary degraders	340:356	primary degraders that utilize extracellular xylanases to cleave xylan into smaller oligomers	340:432	They are initially broken down by primary degraders that utilize extracellular xylanases to cleave xylan into smaller oligomers.					
36200766	11	110	theme	xylan	1926:1930	arg1	degraders					1913:1921	primary degraders	1905:1921	primary degraders of xylan	1905:1930	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	9	111	theme	Extracellular	1352:1364	arg1	activity					1378:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity	1352:1385	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	0	112	theme	pseudocatenulatum	24:40	arg1	Role					0:3	Role	0:3	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.	0:103	Role of Bifidobacterium pseudocatenulatum in Degradation and Consumption of Xylan-Derived Carbohydrates.					
36200766	5	113	theme	Bifidobacterium	616:630	arg1	species					632:638	several Bifidobacterium species	608:638	several Bifidobacterium species	608:638	While several Bifidobacterium species have metabolic systems for XOS, most grow poorly on longer-chain XOS and xylan substrates.					
36200766	3	114	theme	extracellular	371:383	arg1	xylanases					385:393	extracellular xylanases	371:393	extracellular xylanases	371:393	They are initially broken down by primary degraders that utilize extracellular xylanases to cleave xylan into smaller oligomers.					
36200766	14	115	theme	dysbiotic	2286:2294	arg1	microbiota					2296:2305	a disrupted or dysbiotic microbiota	2271:2305	a disrupted or dysbiotic microbiota	2271:2305	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	3	116	theme	smaller	416:422	arg1	oligomers					424:432	smaller oligomers	416:432	smaller oligomers	416:432	They are initially broken down by primary degraders that utilize extracellular xylanases to cleave xylan into smaller oligomers.					
36200766	11	117	theme	extracellular	1940:1952	arg1	degradation					1964:1974	extracellular enzymatic degradation	1940:1974	extracellular enzymatic degradation	1940:1974	These results indicate that xylan+ B. pseudocatenulatum strains may have a competitive advantage in the complex environment of the gastrointestinal tract, due to their ability to act as primary degraders of xylan through extracellular enzymatic degradation.					
36200766	7	118	theme	endo-β-1.4	1154:1163	arg1	enzyme					1181:1186	a key enzyme	1175:1186	a key enzyme for primary degradation of xylan	1175:1219	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	7	118	theme	endo-β-1.4	1154:1163	arg1	xylanase					1165:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	an extracellular GH10 endo-β-1.4 xylanase	1132:1172	In silico analyses revealed that only the genomes of these xylan-fermenting (xylan+) strains contained an extracellular GH10 endo-β-1.4 xylanase, a key enzyme for primary degradation of xylan.					
36200766	16	119	theme	xylans	2712:2717	arg1	utilization					2697:2707	cooperative utilization	2685:2707	cooperative utilization of xylans	2685:2717	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	4	120	theme	secondary	554:562	arg1	consumers					564:572	cross-feed secondary consumers	543:572	cross-feed secondary consumers	543:572	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	4	120	theme	secondary	554:562	arg1	Bifidobacterium					585:599	Bifidobacterium	585:599	Bifidobacterium	585:599	The resulting xylooligosaccharides (XOS) can either be further metabolized directly by primary degraders or cross-feed secondary consumers, including Bifidobacterium.					
36200766	2	121	theme	large	223:227	arg1	intestine					229:237	the large intestine intact	219:244	the large intestine intact; there, they are utilized by members of the gut microbiota	219:303	They therefore reach the large intestine intact; there, they are utilized by members of the gut microbiota.					
36200766	14	122	contain	has	2196:2198	arg2	impact					2211:2216	a profound impact	2200:2216	a profound impact	2200:2216	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	14	122	contain	has	2196:2198	arg1	"					2189:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap"	2164:2189	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
36200766	9	123	dep	6	1490:1490	arg1	to					1487:1488	to	1487:1488	to	1487:1488	Extracellular xylanolytic activity was only detected in xylan+ strains, as indicated by the production of XOS fragments with a DP of 2 to 6, identified by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).					
36200766	10	124	theme	xylan	1696:1700	arg1	supplementation					1702:1716	xylan supplementation	1696:1716	xylan supplementation	1696:1716	Additionally, in vitro fecal fermentations revealed that strains with a xylan+ phenotype can persist with xylan supplementation.					
36200766	16	125	theme	biochemical	2552:2562	arg1	evidence					2576:2583	biochemical and genetic evidence	2552:2583	biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum	2552:2664	The results described here provide biochemical and genetic evidence for primary xylan utilization by human-derived Bifidobacterium pseudocatenulatum and show also that cooperative utilization of xylans occurs among other members of this species.					
36200766	14	126	theme	gut	2244:2246	arg1	microbiome					2248:2257	the gut microbiome	2240:2257	the gut microbiome	2240:2257	This so-called "fiber gap" also has a profound impact on the composition of the gut microbiome, leading to a disrupted or dysbiotic microbiota.					
35960156	3	0	from	participants	700:711	arg1	n = 306					683:689	n = 306	683:689	n = 306	683:689	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	0	from	participants	700:711	arg1	biofilms					673:680	biofilms	673:680	biofilms (n = 306)	673:690	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	0	from	participants	700:711	arg1	abundance					600:608	the abundance	596:608	the abundance	596:608	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	0	from	participants	700:711	arg1	distribution					622:633	spatial distribution	614:633	spatial distribution	614:633	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	9	1	theme	spp.	1668:1671	arg1	abundances					1628:1637	reduced abundances	1620:1637	reduced abundances of Neisseria and Haemophilus spp.	1620:1671	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	4	2	theme	AAL	881:883	arg1	LEA					901:903	AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA	881:933	LEA	901:903	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	2	theme	AAL	881:883	arg1	lectins					830:836	10 fluorescently labeled lectins	805:836	10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA)	805:934	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	8	3	theme	AAL	1430:1432	arg1	biovolumes					1442:1451	AAL and ASA biovolumes	1430:1451	AAL and ASA biovolumes	1430:1451	AAL and ASA biovolumes were increased in SUC biofilms, but the difference was not significant due to considerable biological variation.					
35960156	3	4	theme	present	514:520	arg1	study					522:526	The present study	510:526	The present study	510:526	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	4	5	theme	image	984:988	arg1	analysis					990:997	digital image analysis	976:997	digital image analysis	976:997	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	1	6	theme	matrix	245:250	arg1	glycoconjugates					169:183	glycoconjugates	169:183	glycoconjugates	169:183	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	6	theme	matrix	245:250	arg1	components					149:158	Carbohydrate components	136:158	Carbohydrate components	136:158	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	6	theme	matrix	245:250	arg1	polysaccharides					189:203	polysaccharides	189:203	polysaccharides	189:203	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	6	theme	matrix	245:250	arg1	constituents					210:221	constituents	210:221	constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence	210:313	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	2	7	theme	dental	493:498	arg1	biofilms					500:507	situ-grown dental biofilms	482:507	situ-grown dental biofilms	482:507	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	10	8	theme	dental	1940:1945	arg1	biofilms					1947:1954	situ-grown dental biofilms	1929:1954	situ-grown dental biofilms	1929:1954	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	6	9	theme	situ-grown	1290:1299	arg1	biofilms					1308:1315	situ-grown dental biofilms	1290:1315	situ-grown dental biofilms	1290:1315	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	2	10	from	carbohydrates	453:465	arg1	complex					470:476	complex	470:476	complex	470:476	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	10	11	from	components	1903:1912	arg1	complex					1917:1923	complex	1917:1923	complex	1917:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	2	12	from	Exopolysaccharides	316:333	arg1	biofilms					359:366	Streptococcus mutans biofilms	338:366	Streptococcus mutans biofilms	338:366	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	0	13	dep	presence	104:111	arg1	the					100:102	the	100:102	the	100:102	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	6	14	theme	biovolume	1192:1200	arg1	%					1173:1173	19.3% to 194.0%	1159:1173	19.3% to 194.0% of the microbial biovolume	1159:1200	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	14	theme	biovolume	1192:1200	arg1	biovolume					1192:1200	the microbial biovolume	1178:1200	the microbial biovolume	1178:1200	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	9	15	theme	SUC	1566:1568	arg1	biofilms					1570:1577	SUC biofilms	1566:1577	SUC biofilms	1566:1577	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	6	16	theme	considerable	1114:1125	arg1	biovolumes					1134:1143	considerable matrix biovolumes	1114:1143	considerable matrix biovolumes	1114:1143	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	3	17	from	distribution	622:633	arg1	n = 306					683:689	n = 306	683:689	n = 306	683:689	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	17	from	distribution	622:633	arg1	biofilms					673:680	biofilms	673:680	biofilms (n = 306)	673:690	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	17	from	distribution	622:633	arg1	participants					700:711	10 participants	697:711	10 participants	697:711	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	9	18	theme	significant	1681:1691	arg1	correlations					1693:1704	no significant correlations	1678:1704	no significant correlations between lectin-stained biovolumes and bacterial abundance	1678:1762	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	0	19	from	components	53:62	arg1	biofilms					74:81	dental biofilms	67:81	dental biofilms	67:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	4	20	theme	different	843:851	arg1	specificities					866:878	different carbohydrate specificities	843:878	different carbohydrate specificities	843:878	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	3	21	theme	lectin	550:555	arg1	analysis					565:572	fluorescence lectin binding analysis	537:572	fluorescence lectin binding analysis (FLBA)	537:579	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	21	theme	lectin	550:555	arg1	FLBA					575:578	FLBA	575:578	FLBA	575:578	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	9	22	theme	lectin-stained	1714:1727	arg1	biovolumes					1729:1738	lectin-stained biovolumes	1714:1738	lectin-stained biovolumes	1714:1738	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	6	23	theme	compounds	1274:1282	arg1	variety					1250:1256	a remarkable variety	1237:1256	a remarkable variety of carbohydrate compounds	1237:1282	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	23	theme	compounds	1274:1282	arg1	compounds					1274:1282	carbohydrate compounds	1261:1282	carbohydrate compounds	1261:1282	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	5	24	theme	gene	1049:1052	arg1	sequencing					1054:1063	rRNA gene sequencing	1044:1063	rRNA gene sequencing	1044:1063	Microbial composition was determined by 16S rRNA gene sequencing.					
35960156	2	25	theme	situ-grown	482:491	arg1	biofilms					500:507	situ-grown dental biofilms	482:507	situ-grown dental biofilms	482:507	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	10	26	from	complex	1917:1923	arg1	components					1903:1912	different carbohydrate components	1880:1912	different carbohydrate components in complex	1880:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	10	26	from	complex	1917:1923	arg1	variety					1869:1875	a variety	1867:1875	a variety of different carbohydrate components in complex	1867:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	3	27	theme	binding	557:563	arg1	analysis					565:572	fluorescence lectin binding analysis	537:572	fluorescence lectin binding analysis (FLBA)	537:579	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	27	theme	binding	557:563	arg1	FLBA					575:578	FLBA	575:578	FLBA	575:578	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	0	28	theme	lectin	13:18	arg1	analysis					28:35	Fluorescence lectin binding analysis	0:35	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms	0:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	6	29	theme	dental	1301:1306	arg1	biofilms					1308:1315	situ-grown dental biofilms	1290:1315	situ-grown dental biofilms	1290:1315	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	10	30	theme	voluminous	1830:1839	arg1	matrix					1849:1854	a voluminous biofilm matrix	1828:1854	a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex	1828:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	3	31	theme	H2O	752:754	arg1	exposure					757:764	(H2O) exposure	751:764	(H2O) exposure to sucrose	751:775	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	5	32	theme	rRNA	1044:1047	arg1	sequencing					1054:1063	rRNA gene sequencing	1044:1063	rRNA gene sequencing	1044:1063	Microbial composition was determined by 16S rRNA gene sequencing.					
35960156	0	33	theme	Fluorescence	0:11	arg1	analysis					28:35	Fluorescence lectin binding analysis	0:35	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms	0:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	1	34	theme	important	265:273	arg1	role					275:278	an important role	262:278	an important role	262:278	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	4	35	theme	carbohydrate	853:864	arg1	specificities					866:878	different carbohydrate specificities	843:878	different carbohydrate specificities	843:878	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	36	theme	confocal	952:959	arg1	microscopy					961:970	confocal microscopy	952:970	confocal microscopy	952:970	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	2	37	theme	matrix	446:451	arg1	carbohydrates					453:465	the matrix carbohydrates	442:465	the matrix carbohydrates in complex	442:476	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	8	38	theme	ASA	1438:1440	arg1	biovolumes					1442:1451	AAL and ASA biovolumes	1430:1451	AAL and ASA biovolumes	1430:1451	AAL and ASA biovolumes were increased in SUC biofilms, but the difference was not significant due to considerable biological variation.					
35960156	6	39	theme	carbohydrate	1261:1272	arg1	compounds					1274:1282	carbohydrate compounds	1261:1282	carbohydrate compounds	1261:1282	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	40	theme	ABA	1088:1090	arg1	exception					1075:1083	the exception	1071:1083	the exception of ABA	1071:1090	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	3	41	from	abundance	600:608	arg1	n = 306					683:689	n = 306	683:689	n = 306	683:689	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	41	from	abundance	600:608	arg1	biofilms					673:680	biofilms	673:680	biofilms (n = 306)	673:690	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	41	from	abundance	600:608	arg1	participants					700:711	10 participants	697:711	10 participants	697:711	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	0	42	theme	binding	20:26	arg1	analysis					28:35	Fluorescence lectin binding analysis	0:35	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms	0:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	10	43	theme	different	1880:1888	arg1	components					1903:1912	different carbohydrate components	1880:1912	different carbohydrate components in complex	1880:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	0	44	theme	carbohydrate	40:51	arg1	components					53:62	carbohydrate components	40:62	carbohydrate components in dental biofilms	40:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	1	45	theme	biofilm	283:289	arg1	stability					291:299	biofilm stability	283:299	biofilm stability	283:299	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	0	46	theme	sucrose	127:133	arg1	absence					116:122	absence	116:122	absence	116:122	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	0	46	theme	sucrose	127:133	arg1	presence					104:111	presence	104:111	presence	104:111	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	10	47	theme	matrix	1849:1854	arg1	presence					1816:1823	the presence	1812:1823	the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex	1812:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	4	48	theme	digital	976:982	arg1	analysis					990:997	digital image analysis	976:997	digital image analysis	976:997	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	8	49	theme	SUC	1471:1473	arg1	biofilms					1475:1482	SUC biofilms	1471:1482	SUC biofilms	1471:1482	AAL and ASA biovolumes were increased in SUC biofilms, but the difference was not significant due to considerable biological variation.					
35960156	6	50	theme	remarkable	1239:1248	arg1	variety					1250:1256	a remarkable variety	1237:1256	a remarkable variety of carbohydrate compounds	1237:1282	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	50	theme	remarkable	1239:1248	arg1	compounds					1274:1282	carbohydrate compounds	1261:1282	carbohydrate compounds	1261:1282	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	0	51	from	biofilms	74:81	arg1	analysis					28:35	Fluorescence lectin binding analysis	0:35	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms	0:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	3	52	theme	spatial	614:620	arg1	distribution					622:633	spatial distribution	614:633	spatial distribution	614:633	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	10	53	theme	carbohydrate	1890:1901	arg1	components					1903:1912	different carbohydrate components	1880:1912	different carbohydrate components in complex	1880:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	10	54	from	variety	1869:1875	arg1	complex					1917:1923	complex	1917:1923	complex	1917:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	9	55	theme	reduced	1620:1626	arg1	abundances					1628:1637	reduced abundances	1620:1637	reduced abundances of Neisseria and Haemophilus spp.	1620:1671	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	6	56	dep	%	1173:1173	arg1	to					1165:1166	to	1165:1166	to	1165:1166	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	57	theme	%	1163:1163	arg1	%					1173:1173	19.3% to 194.0%	1159:1173	19.3% to 194.0% of the microbial biovolume	1159:1200	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	57	theme	%	1163:1163	arg1	biovolume					1192:1200	the microbial biovolume	1178:1200	the microbial biovolume	1178:1200	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	2	58	theme	mutans	352:357	arg1	biofilms					359:366	Streptococcus mutans biofilms	338:366	Streptococcus mutans biofilms	338:366	Exopolysaccharides in Streptococcus mutans biofilms have been characterized extensively, but comparably little is known about the matrix carbohydrates in complex, in situ-grown dental biofilms.					
35960156	0	59	theme	components	53:62	arg1	analysis					28:35	Fluorescence lectin binding analysis	0:35	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms	0:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	10	60	theme	biofilm	1841:1847	arg1	matrix					1849:1854	a voluminous biofilm matrix	1828:1854	a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex	1828:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	4	61	theme	labeled	822:828	arg1	LEA					901:903	AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA	881:933	LEA	901:903	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	MNA-G					906:910	MNA-G	906:910	MNA-G	906:910	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	VGA					923:925	VGA	923:925	VGA	923:925	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	ASA					891:893	AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA	881:933	ASA	891:893	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	WGA					931:933	WGA	931:933	WGA	931:933	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	HPA					896:898	AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA	881:933	HPA	896:898	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	MPA					913:915	MPA	913:915	MPA	913:915	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	lectins					830:836	10 fluorescently labeled lectins	805:836	10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA)	805:934	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	PSA					918:920	PSA	918:920	PSA	918:920	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	4	61	theme	labeled	822:828	arg1	ABA					886:888	AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA	881:933	ABA	886:888	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	10	62	theme	components	1903:1912	arg1	components					1903:1912	different carbohydrate components	1880:1912	different carbohydrate components in complex	1880:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	10	62	theme	components	1903:1912	arg1	variety					1869:1875	a variety	1867:1875	a variety of different carbohydrate components in complex	1867:1923	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	8	63	theme	biological	1544:1553	arg1	variation					1555:1563	considerable biological variation	1531:1563	considerable biological variation	1531:1563	AAL and ASA biovolumes were increased in SUC biofilms, but the difference was not significant due to considerable biological variation.					
35960156	7	64	theme	specific	1339:1346	arg1	MNA-G					1318:1322	MNA-G	1318:1322	MNA-G	1318:1322	MNA-G, AAL, and ASA, specific for galactose, fucose, and mannose, respectively, stained the largest biovolumes.					
35960156	7	65	theme	largest	1410:1416	arg1	biovolumes					1418:1427	the largest biovolumes	1406:1427	the largest biovolumes	1406:1427	MNA-G, AAL, and ASA, specific for galactose, fucose, and mannose, respectively, stained the largest biovolumes.					
35960156	3	66	theme	glycoconjugates/polysaccharides	638:668	arg1	abundance					600:608	the abundance	596:608	the abundance	596:608	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	66	theme	glycoconjugates/polysaccharides	638:668	arg1	distribution					622:633	spatial distribution	614:633	spatial distribution	614:633	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	8	67	theme	considerable	1531:1542	arg1	variation					1555:1563	considerable biological variation	1531:1563	considerable biological variation	1531:1563	AAL and ASA biovolumes were increased in SUC biofilms, but the difference was not significant due to considerable biological variation.					
35960156	4	68	with	lectins	830:836	arg1	specificities					866:878	different carbohydrate specificities	843:878	different carbohydrate specificities	843:878	Biofilms were stained with 10 fluorescently labeled lectins with different carbohydrate specificities (AAL, ABA, ASA, HPA, LEA, MNA-G, MPA, PSA, VGA and WGA) and analyzed by confocal microscopy and digital image analysis.					
35960156	9	69	theme	Neisseria	1642:1650	arg1	abundances					1628:1637	reduced abundances	1620:1637	reduced abundances of Neisseria and Haemophilus spp.	1620:1671	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	6	70	theme	microbial	1182:1190	arg1	biovolume					1192:1200	the microbial biovolume	1178:1200	the microbial biovolume	1178:1200	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	6	71	theme	matrix	1127:1132	arg1	biovolumes					1134:1143	considerable matrix biovolumes	1114:1143	considerable matrix biovolumes	1114:1143	With the exception of ABA, all lectins targeted considerable matrix biovolumes, ranging from 19.3% to 194.0% of the microbial biovolume in the biofilms, which illustrates a remarkable variety of carbohydrate compounds in in situ-grown dental biofilms.					
35960156	3	72	theme	fluorescence	537:548	arg1	analysis					565:572	fluorescence lectin binding analysis	537:572	fluorescence lectin binding analysis (FLBA)	537:579	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	3	72	theme	fluorescence	537:548	arg1	FLBA					575:578	FLBA	575:578	FLBA	575:578	The present study employed fluorescence lectin binding analysis (FLBA) to investigate the abundance and spatial distribution of glycoconjugates/polysaccharides in biofilms (n = 306) from 10 participants, grown in situ with (SUC) and without (H2O) exposure to sucrose.					
35960156	9	73	theme	bacterial	1744:1752	arg1	abundance					1754:1762	bacterial abundance	1744:1762	bacterial abundance	1744:1762	SUC biofilms were enriched in streptococci and showed reduced abundances of Neisseria and Haemophilus spp., but no significant correlations between lectin-stained biovolumes and bacterial abundance were observed.					
35960156	5	74	theme	Microbial	1000:1008	arg1	composition					1010:1020	Microbial composition	1000:1020	Microbial composition	1000:1020	Microbial composition was determined by 16S rRNA gene sequencing.					
35960156	1	75	theme	dental	230:235	arg1	matrix					245:250	the dental biofilm matrix	226:250	the dental biofilm matrix	226:250	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	0	76	theme	dental	67:72	arg1	biofilms					74:81	dental biofilms	67:81	dental biofilms	67:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	0	77	from	analysis	28:35	arg1	biofilms					74:81	dental biofilms	67:81	dental biofilms	67:81	Fluorescence lectin binding analysis of carbohydrate components in dental biofilms grown in situ in the presence or absence of sucrose.					
35960156	10	78	theme	situ-grown	1929:1938	arg1	biofilms					1947:1954	situ-grown dental biofilms	1929:1954	situ-grown dental biofilms	1929:1954	In conclusion, FLBA demonstrates the presence of a voluminous biofilm matrix comprising a variety of different carbohydrate components in complex, in situ-grown dental biofilms.					
35960156	1	79	theme	Carbohydrate	136:147	arg1	glycoconjugates					169:183	glycoconjugates	169:183	glycoconjugates	169:183	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	79	theme	Carbohydrate	136:147	arg1	components					149:158	Carbohydrate components	136:158	Carbohydrate components	136:158	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	79	theme	Carbohydrate	136:147	arg1	polysaccharides					189:203	polysaccharides	189:203	polysaccharides	189:203	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	79	theme	Carbohydrate	136:147	arg1	constituents					210:221	constituents	210:221	constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence	210:313	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
35960156	1	80	theme	biofilm	237:243	arg1	matrix					245:250	the dental biofilm matrix	226:250	the dental biofilm matrix	226:250	Carbohydrate components, such as glycoconjugates and polysaccharides, are constituents of the dental biofilm matrix that play an important role in biofilm stability and virulence.					
36690639	0	0	from	channels	19:26	arg1	membranes					45:53	layered MXene membranes	31:53	layered MXene membranes	31:53	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	5	1	theme	enhanced	857:864	arg1	current					879:885	enhanced photothermal current	857:885	enhanced photothermal current	857:885	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	1	2	theme	ion-transport-mediated	165:186	arg1	signaling					188:196	ion-transport-mediated signaling	165:196	ion-transport-mediated signaling	165:196	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	2	3	from	embedded	458:465	arg1	nanosheets					484:493	layered MXene nanosheets	470:493	layered MXene nanosheets	470:493	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	6	4	theme	ionic	1205:1209	arg1	circuits					1211:1218	light-controlled ionic circuits	1188:1218	light-controlled ionic circuits	1188:1218	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	0	5	theme	gold	79:82	arg1	nanostars					84:92	plasmonic gold nanostars	69:92	plasmonic gold nanostars	69:92	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	6	6	theme	MAC	1090:1092	arg1	membranes					1104:1112	The MAC composite membranes	1086:1112	The MAC composite membranes	1086:1112	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	2	7	theme	photosensitive	357:370	arg1	channel					376:382	a photosensitive ion channel	355:382	a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets	355:493	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	1	8	theme	energy	276:281	arg1	devices					294:300	energy harvesting devices	276:300	energy harvesting devices	276:300	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	0	9	theme	cellulose	98:106	arg1	nanofibers					108:117	cellulose nanofibers	98:117	cellulose nanofibers	98:117	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	6	10	with	channels	1161:1168	arg1	ionogels					1175:1182	ionogels	1175:1182	ionogels	1175:1182	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	6	10	with	channels	1161:1168	arg1	circuits					1211:1218	light-controlled ionic circuits	1188:1218	light-controlled ionic circuits	1188:1218	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	3	11	theme	subnanometer-sized	539:556	arg1	pathways					564:571	subnanometer-sized ionic pathways	539:571	subnanometer-sized ionic pathways for light-sensitive cationic flow	539:605	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	1	12	theme	harvesting	283:292	arg1	devices					294:300	energy harvesting devices	276:300	energy harvesting devices	276:300	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	4	13	theme	electrolyte	760:770	arg1	flow					739:742	directional photothermo-osmotic flow	707:742	directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient	707:799	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	2	14	attach	present	347:353	arg2	we					344:345	we	344:345	we	344:345	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	2	14	attach	present	347:353	arg1	work					338:341	this work	333:341	this work	333:341	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	3	15	theme	ionic	558:562	arg1	pathways					564:571	subnanometer-sized ionic pathways	539:571	subnanometer-sized ionic pathways for light-sensitive cationic flow	539:605	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	2	16	theme	ion	372:374	arg1	channel					376:382	a photosensitive ion channel	355:382	a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets	355:493	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	6	17	theme	flexible	1146:1153	arg1	channels					1161:1168	flexible ionic channels	1146:1168	flexible ionic channels with ionogels and light-controlled ionic circuits	1146:1218	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	4	18	theme	photothermo-osmotic	719:737	arg1	flow					739:742	directional photothermo-osmotic flow	707:742	directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient	707:799	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	4	19	theme	photothermal	660:671	arg1	gradient					673:680	a photothermal gradient	658:680	a photothermal gradient	658:680	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	2	20	theme	layered	470:476	arg1	nanosheets					484:493	layered MXene nanosheets	470:493	layered MXene nanosheets	470:493	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	5	21	theme	MAC	835:837	arg1	membrane					839:846	MAC membrane	835:846	MAC membrane	835:846	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	2	22	theme	gold	403:406	arg1	AuNSs					419:423	AuNSs	419:423	AuNSs	419:423	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	2	22	theme	gold	403:406	arg1	nanostars					408:416	plasmonic gold nanostars	393:416	plasmonic gold nanostars (AuNSs)	393:424	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	0	23	theme	ion	15:17	arg1	channels					19:26	Photosensitive ion channels	0:26	Photosensitive ion channels in layered MXene membranes	0:53	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	2	24	theme	MXene	478:482	arg1	nanosheets					484:493	layered MXene nanosheets	470:493	layered MXene nanosheets	470:493	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	3	25	theme	light-sensitive	577:591	arg1	flow					602:605	light-sensitive cationic flow	577:605	light-sensitive cationic flow	577:605	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	2	26	theme	plasmonic	393:401	arg1	AuNSs					419:423	AuNSs	419:423	AuNSs	419:423	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	2	26	theme	plasmonic	393:401	arg1	nanostars					408:416	plasmonic gold nanostars	393:416	plasmonic gold nanostars (AuNSs)	393:424	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	0	27	theme	Photosensitive	0:13	arg1	channels					19:26	Photosensitive ion channels	0:26	Photosensitive ion channels in layered MXene membranes	0:53	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	3	28	theme	cationic	593:600	arg1	flow					602:605	light-sensitive cationic flow	577:605	light-sensitive cationic flow	577:605	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	6	29	theme	composite	1094:1102	arg1	membranes					1104:1112	The MAC composite membranes	1086:1112	The MAC composite membranes	1086:1112	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	4	30	theme	nanoconfined	747:758	arg1	electrolyte					760:770	nanoconfined electrolyte	747:770	nanoconfined electrolyte against the thermal gradient	747:799	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	5	31	theme	AuNSs	987:991	arg1	effects					966:972	the combined photothermal effects	940:972	the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils	940:1083	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	1	32	theme	considerable	218:229	arg1	attention					231:239	considerable attention	218:239	considerable attention	218:239	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	2	33	theme	cellulose	430:438	arg1	CNFs					452:455	CNFs	452:455	CNFs	452:455	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	2	33	theme	cellulose	430:438	arg1	nanofibers					440:449	cellulose nanofibers	430:449	cellulose nanofibers (CNFs)	430:456	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	1	34	theme	desalination	307:318	arg1	membrane					320:327	desalination membrane	307:327	desalination membrane	307:327	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	5	35	theme	plasmonic	977:985	arg1	AuNSs					987:991	plasmonic AuNSs	977:991	plasmonic AuNSs	977:991	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	2	36	from	nanosheets	484:493	arg1	embedded					458:465	embedded	458:465	embedded	458:465	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	5	37	theme	photothermal	866:877	arg1	current					879:885	enhanced photothermal current	857:885	enhanced photothermal current	857:885	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	0	38	theme	MXene	39:43	arg1	membranes					45:53	layered MXene membranes	31:53	layered MXene membranes	31:53	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	5	39	theme	combined	944:951	arg1	effects					966:972	the combined photothermal effects	940:972	the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils	940:1083	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	5	40	theme	composite	1043:1051	arg1	AuNSs					987:991	plasmonic AuNSs	977:991	plasmonic AuNSs	977:991	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	5	40	theme	composite	1043:1051	arg1	interspacing					1019:1030	the widened interspacing	1007:1030	the widened interspacing of the MAC composite	1007:1051	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	5	40	theme	composite	1043:1051	arg1	MXene					997:1001	MXene	997:1001	MXene	997:1001	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	0	41	theme	layered	31:37	arg1	membranes					45:53	layered MXene membranes	31:53	layered MXene membranes	31:53	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	4	42	theme	thermal	784:790	arg1	gradient					792:799	the thermal gradient	780:799	the thermal gradient	780:799	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	1	43	theme	diverse	244:250	arg1	fields					252:257	diverse fields	244:257	diverse fields such as sensors, energy harvesting devices, and desalination membrane	244:327	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	1	43	theme	diverse	244:250	arg1	sensors					267:273	sensors	267:273	sensors	267:273	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	1	43	theme	diverse	244:250	arg1	membrane					320:327	desalination membrane	307:327	desalination membrane	307:327	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	1	43	theme	diverse	244:250	arg1	devices					294:300	energy harvesting devices	276:300	energy harvesting devices	276:300	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	2	44	theme	embedded	458:465	arg1	AuNSs					419:423	AuNSs	419:423	AuNSs	419:423	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	2	44	theme	embedded	458:465	arg1	nanostars					408:416	plasmonic gold nanostars	393:416	plasmonic gold nanostars (AuNSs)	393:424	In this work, we present a photosensitive ion channel based on plasmonic gold nanostars (AuNSs) and cellulose nanofibers (CNFs) embedded in layered MXene nanosheets.					
36690639	3	45	theme	MXene/AuNS/CNF	500:513	arg1	membrane					521:528	The MXene/AuNS/CNF (MAC) membrane	496:528	The MXene/AuNS/CNF (MAC) membrane	496:528	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	6	46	theme	ionic	1155:1159	arg1	channels					1161:1168	flexible ionic channels	1146:1168	flexible ionic channels with ionogels and light-controlled ionic circuits	1146:1218	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	1	47	theme	Ion	120:122	arg1	channels					124:131	Ion channels	120:131	Ion channels	120:131	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	5	48	theme	hydrophilic	1061:1071	arg1	nanofibrils					1073:1083	the hydrophilic nanofibrils	1057:1083	the hydrophilic nanofibrils	1057:1083	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	4	49	theme	directional	707:717	arg1	flow					739:742	directional photothermo-osmotic flow	707:742	directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient	707:799	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	5	50	theme	MAC	1039:1041	arg1	composite					1043:1051	the MAC composite	1035:1051	the MAC composite	1035:1051	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	4	51	theme	net	816:818	arg1	current					826:832	a net ionic current	814:832	a net ionic current	814:832	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	5	52	theme	photothermal	953:964	arg1	effects					966:972	the combined photothermal effects	940:972	the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils	940:1083	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	5	53	theme	widened	1011:1017	arg1	interspacing					1019:1030	the widened interspacing	1007:1030	the widened interspacing of the MAC composite	1007:1051	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	5	54	theme	MXene	997:1001	arg1	effects					966:972	the combined photothermal effects	940:972	the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils	940:1083	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	1	55	theme	external	143:150	arg1	stimuli					152:158	external stimuli	143:158	external stimuli	143:158	Ion channels transduce external stimuli into ion-transport-mediated signaling, which has received considerable attention in diverse fields such as sensors, energy harvesting devices, and desalination membrane.					
36690639	4	56	theme	MAC	617:619	arg1	nanochannel					621:631	the MAC nanochannel	613:631	the MAC nanochannel	613:631	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	0	57	theme	plasmonic	69:77	arg1	nanostars					84:92	plasmonic gold nanostars	69:92	plasmonic gold nanostars	69:92	Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers.					
36690639	4	58	theme	NIR	647:649	arg1	light					651:655	NIR light	647:655	NIR light	647:655	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36690639	3	59	theme	MAC	516:518	arg1	membrane					521:528	The MXene/AuNS/CNF (MAC) membrane	496:528	The MXene/AuNS/CNF (MAC) membrane	496:528	The MXene/AuNS/CNF (MAC) membrane provides subnanometer-sized ionic pathways for light-sensitive cationic flow.					
36690639	5	60	theme	pristine	901:908	arg1	MXene					910:914	pristine MXene	901:914	pristine MXene	901:914	MAC membrane exhibits enhanced photothermal current compared with pristine MXene, which is attributed to the combined photothermal effects of plasmonic AuNSs and MXene and the widened interspacing of the MAC composite via the hydrophilic nanofibrils.					
36690639	6	61	theme	light-controlled	1188:1203	arg1	circuits					1211:1218	light-controlled ionic circuits	1188:1218	light-controlled ionic circuits	1188:1218	The MAC composite membranes are envisioned to be applied in flexible ionic channels with ionogels and light-controlled ionic circuits.					
36690639	4	62	theme	ionic	820:824	arg1	current					826:832	a net ionic current	814:832	a net ionic current	814:832	When the MAC nanochannel is exposed to NIR light, a photothermal gradient is formed, which induces directional photothermo-osmotic flow of nanoconfined electrolyte against the thermal gradient and produces a net ionic current.					
36596205	12	0	theme	probiotic	1964:1972	arg1	strain					1974:1979	the inoculated probiotic strain	1949:1979	the inoculated probiotic strain	1949:1979	This implies that some of the metabolites were produced through the interaction of the fecal microbiota with the inoculated probiotic strain.					
36596205	6	1	theme	other	878:882	arg1	groups					900:905	the other three treatment groups	874:905	the other three treatment groups	874:905	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	5	2	theme	Principal	631:639	arg1	PCoA					662:665	PCoA	662:665	PCoA	662:665	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	5	2	theme	Principal	631:639	arg1	analysis					652:659	Principal coordinate analysis	631:659	Principal coordinate analysis (PCoA)	631:666	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	11	3	theme	strain	1801:1806	arg1	monocultures					1771:1782	the monocultures	1767:1782	the monocultures of the probiotic strain with or without the prebiotics	1767:1837	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	13	4	theme	fecal	2099:2103	arg1	genus					2116:2120	the fecal microbiota genus	2095:2120	the fecal microbiota genus	2095:2120	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	7	5	theme	Blautia	934:940	arg1	highest					950:956	highest	950:956	highest	950:956	The relative abundance of Blautia was the highest in the control group among the four groups.					
36596205	7	5	theme	Blautia	934:940	arg1	abundance					921:929	The relative abundance	908:929	The relative abundance of Blautia	908:940	The relative abundance of Blautia was the highest in the control group among the four groups.					
36596205	6	6	theme	relative	767:774	arg1	higher					823:828	higher	823:828	higher	823:828	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	6	6	theme	relative	767:774	arg1	abundance					776:784	The relative abundance	763:784	The relative abundance of Bifidobacterium	763:803	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	9	7	theme	indole-3-lactic	1367:1381	arg1	ILA					1389:1391	ILA	1389:1391	ILA	1389:1391	A clustering based on 46 metabolites indicated that tryptophan-metabolites such as indole-3-lactic acid (ILA), indole-3-ethanol, and indole-3-carboxaldehyde, were included in a sub cluster composed of metabolites enriched in the synbiotic group.					
36596205	9	7	theme	indole-3-lactic	1367:1381	arg1	acid					1383:1386	indole-3-lactic acid	1367:1386	indole-3-lactic acid (ILA)	1367:1392	A clustering based on 46 metabolites indicated that tryptophan-metabolites such as indole-3-lactic acid (ILA), indole-3-ethanol, and indole-3-carboxaldehyde, were included in a sub cluster composed of metabolites enriched in the synbiotic group.					
36596205	12	8	theme	microbiota	1933:1942	arg1	interaction					1908:1918	the interaction	1904:1918	the interaction of the fecal microbiota with the inoculated probiotic strain	1904:1979	This implies that some of the metabolites were produced through the interaction of the fecal microbiota with the inoculated probiotic strain.					
36596205	1	9	contain	have	168:171	arg1	Probiotics					142:151	Probiotics	142:151	Probiotics	142:151	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	1	9	contain	have	168:171	arg2	effects					184:190	beneficial effects	173:190	beneficial effects on host physiology	173:209	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	1	9	contain	have	168:171	arg1	prebiotics					157:166	prebiotics	157:166	prebiotics	157:166	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	10	10	theme	synbiotic	1666:1674	arg1	group					1676:1680	the synbiotic group	1662:1680	the synbiotic group	1662:1680	Spermidine, a major polyamine, was enriched in the two groups supplemented with the probiotic whereas spermine was enriched only in the synbiotic group.					
36596205	1	11	theme	host	195:198	arg1	physiology					200:209	host physiology	195:209	host physiology	195:209	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	17	12	theme	molecular	2584:2592	arg1	level					2594:2598	the molecular level	2580:2598	the molecular level	2580:2598	Our results provide an insight into more effective administration of probiotics at the molecular level.					
36596205	3	13	theme	gut	538:540	arg1	environment					542:552	the gut environment	534:552	the gut environment	534:552	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	8	14	theme	metabolites	1193:1203	arg1	17					1168:1169	17	1168:1169	17	1168:1169	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	8	14	theme	metabolites	1193:1203	arg1	metabolites					1193:1203	the 107 lipophilic metabolites	1174:1203	the 107 lipophilic metabolites	1174:1203	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	13	15	from	differences	2029:2039	arg1	correlations					2048:2059	the correlations	2044:2059	the correlations between the relative abundance of the fecal microbiota genus	2044:2120	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	13	15	from	differences	2029:2039	arg1	group					2161:2165	each group	2156:2165	each group	2156:2165	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	13	15	from	differences	2029:2039	arg1	metabolites					2141:2151	the tryptophan metabolites	2126:2151	the tryptophan metabolites	2126:2151	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	1	16	theme	gut	236:238	arg1	microbiota					240:249	the gut microbiota	232:249	the gut microbiota	232:249	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	8	17	theme	hydrophilic	1140:1150	arg1	metabolites					1152:1162	the 310 hydrophilic metabolites	1132:1162	the 310 hydrophilic metabolites	1132:1162	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	0	18	from	production	67:76	arg1	communities					129:139	fermented human fecal communities	107:139	fermented human fecal communities	107:139	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	10	19	theme	major	1544:1548	arg1	polyamine					1550:1558	a major polyamine	1542:1558	a major polyamine	1542:1558	Spermidine, a major polyamine, was enriched in the two groups supplemented with the probiotic whereas spermine was enriched only in the synbiotic group.					
36596205	10	19	theme	major	1544:1548	arg1	Spermidine					1530:1539	Spermidine	1530:1539	Spermidine	1530:1539	Spermidine, a major polyamine, was enriched in the two groups supplemented with the probiotic whereas spermine was enriched only in the synbiotic group.					
36596205	15	20	theme	gene	2300:2303	arg1	higher					2323:2328	higher	2323:2328	higher	2323:2328	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	15	20	theme	gene	2300:2303	arg1	number					2285:2290	The copy number	2276:2290	The copy number of ldh4 gene	2276:2303	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	6	21	theme	treatment	890:898	arg1	groups					900:905	the other three treatment groups	874:905	the other three treatment groups	874:905	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	16	22	theme	gut	2480:2482	arg1	environment					2484:2494	the gut environment	2476:2494	the gut environment	2476:2494	In conclusion, synbiotics could enhance the production of signaling molecules in the gut environment.					
36596205	17	23	theme	probiotics	2566:2575	arg1	administration					2548:2561	more effective administration	2533:2561	more effective administration of probiotics at the molecular level	2533:2598	Our results provide an insight into more effective administration of probiotics at the molecular level.					
36596205	16	24	from	production	2439:2448	arg1	environment					2484:2494	the gut environment	2476:2494	the gut environment	2476:2494	In conclusion, synbiotics could enhance the production of signaling molecules in the gut environment.					
36596205	12	25	with	interaction	1908:1918	arg1	strain					1974:1979	the inoculated probiotic strain	1949:1979	the inoculated probiotic strain	1949:1979	This implies that some of the metabolites were produced through the interaction of the fecal microbiota with the inoculated probiotic strain.					
36596205	4	26	used	used	610:613	arg2	control					622:628	the control	618:628	the control	618:628	Fecal inoculum without the probiotic and prebiotic was used as the control.					
36596205	4	26	used	used	610:613	arg2	inoculum					561:568	Fecal inoculum	555:568	Fecal inoculum without the probiotic and prebiotic	555:604	Fecal inoculum without the probiotic and prebiotic was used as the control.					
36596205	14	27	theme	fecal	2256:2260	arg1	fermentation					2262:2273	the fecal fermentation	2252:2273	the fecal fermentation	2252:2273	There was a strong correlation between ldh4 gene abundance and ILA concentration in the fecal fermentation.					
36596205	0	28	theme	tryptophan	81:90	arg1	metabolites					92:102	tryptophan metabolites	81:102	tryptophan metabolites	81:102	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	13	29	theme	genus	2116:2120	arg1	abundance					2082:2090	the relative abundance	2069:2090	the relative abundance of the fecal microbiota genus	2069:2120	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	8	30	theme	Kruskal-Wallis	1263:1276	arg1	test					1278:1281	the Kruskal-Wallis test	1259:1281	the Kruskal-Wallis test	1259:1281	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	5	31	theme	gut	697:699	arg1	microbiota					701:710	gut microbiota	697:710	gut microbiota	697:710	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	7	32	theme	relative	912:919	arg1	highest					950:956	highest	950:956	highest	950:956	The relative abundance of Blautia was the highest in the control group among the four groups.					
36596205	7	32	theme	relative	912:919	arg1	abundance					921:929	The relative abundance	908:929	The relative abundance of Blautia	908:940	The relative abundance of Blautia was the highest in the control group among the four groups.					
36596205	17	33	from	level	2594:2598	arg1	administration					2548:2561	more effective administration	2533:2561	more effective administration of probiotics at the molecular level	2533:2598	Our results provide an insight into more effective administration of probiotics at the molecular level.					
36596205	14	34	theme	ILA	2231:2233	arg1	concentration					2235:2247	ILA concentration	2231:2247	ILA concentration	2231:2247	There was a strong correlation between ldh4 gene abundance and ILA concentration in the fecal fermentation.					
36596205	0	35	theme	human	117:121	arg1	communities					129:139	fermented human fecal communities	107:139	fermented human fecal communities	107:139	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	13	36	theme	Co-abundance	1982:1993	arg1	analysis					2006:2013	Co-abundance networking analysis	1982:2013	Co-abundance networking analysis	1982:2013	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	3	37	dep	both	486:489	arg1	synbiotic					492:500	synbiotic	492:500	synbiotic	492:500	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	15	38	theme	ldh4	2295:2298	arg1	gene					2300:2303	ldh4 gene	2295:2303	ldh4 gene	2295:2303	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	3	39	theme	fecal	376:380	arg1	fermentation					382:393	fecal fermentation	376:393	fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic)	376:501	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	14	40	theme	ldh4	2207:2210	arg1	abundance					2217:2225	ldh4 gene abundance	2207:2225	ldh4 gene abundance	2207:2225	There was a strong correlation between ldh4 gene abundance and ILA concentration in the fecal fermentation.					
36596205	0	41	theme	Bifidobacterium	14:28	arg1	MCC1274					36:42	Bifidobacterium breve MCC1274	14:42	Bifidobacterium breve MCC1274	14:42	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	0	42	theme	MCC1274	36:42	arg1	Synbiotics					0:9	Synbiotics	0:9	Synbiotics of Bifidobacterium breve MCC1274 and lactulose	0:56	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	3	43	theme	breve	416:420	arg1	MCC1274					422:428	Bifidobacterium breve MCC1274	400:428	Bifidobacterium breve MCC1274 (probiotic)	400:440	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	2	44	theme	microbiota	345:354	arg1	fermenter					320:328	a pH-controlled single-batch fermenter	291:328	a pH-controlled single-batch fermenter	291:328	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	2	44	theme	microbiota	345:354	arg1	model					356:360	a human gut microbiota model	333:360	a human gut microbiota model	333:360	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	0	45	theme	lactulose	48:56	arg1	Synbiotics					0:9	Synbiotics	0:9	Synbiotics of Bifidobacterium breve MCC1274 and lactulose	0:56	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	8	46	theme	metabolites	1050:1060	arg1	number					1040:1045	the number	1036:1045	the number of metabolites detected in the synbiotic group	1036:1092	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	8	46	theme	metabolites	1050:1060	arg1	highest					1102:1108	highest	1102:1108	highest	1102:1108	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	16	47	theme	molecules	2463:2471	arg1	production					2439:2448	the production	2435:2448	the production of signaling molecules in the gut environment	2435:2494	In conclusion, synbiotics could enhance the production of signaling molecules in the gut environment.					
36596205	2	48	theme	human	335:339	arg1	fermenter					320:328	a pH-controlled single-batch fermenter	291:328	a pH-controlled single-batch fermenter	291:328	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	2	48	theme	human	335:339	arg1	model					356:360	a human gut microbiota model	333:360	a human gut microbiota model	333:360	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	15	49	theme	control	2380:2386	arg1	group					2388:2392	the control group	2376:2392	the control group	2376:2392	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	15	50	theme	copy	2280:2283	arg1	higher					2323:2328	higher	2323:2328	higher	2323:2328	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	15	50	theme	copy	2280:2283	arg1	number					2285:2290	The copy number	2276:2290	The copy number of ldh4 gene	2276:2303	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	14	51	theme	strong	2180:2185	arg1	correlation					2187:2197	a strong correlation	2178:2197	a strong correlation between ldh4 gene abundance and ILA concentration	2178:2247	There was a strong correlation between ldh4 gene abundance and ILA concentration in the fecal fermentation.					
36596205	13	52	theme	tryptophan	2130:2139	arg1	metabolites					2141:2151	the tryptophan metabolites	2126:2151	the tryptophan metabolites	2126:2151	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	8	53	theme	synbiotic	1078:1086	arg1	group					1088:1092	the synbiotic group	1074:1092	the synbiotic group	1074:1092	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	5	54	theme	significant	722:732	arg1	difference					734:743	a significant difference	720:743	a significant difference among the groups	720:760	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	11	55	theme	probiotic	1791:1799	arg1	strain					1801:1806	the probiotic strain	1787:1806	the probiotic strain	1787:1806	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	12	56	theme	inoculated	1953:1962	arg1	strain					1974:1979	the inoculated probiotic strain	1949:1979	the inoculated probiotic strain	1949:1979	This implies that some of the metabolites were produced through the interaction of the fecal microbiota with the inoculated probiotic strain.					
36596205	2	57	used	used	286:289	arg2	we					283:284	we	283:284	we	283:284	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	4	58	theme	Fecal	555:559	arg1	control					622:628	the control	618:628	the control	618:628	Fecal inoculum without the probiotic and prebiotic was used as the control.					
36596205	4	58	theme	Fecal	555:559	arg1	inoculum					561:568	Fecal inoculum	555:568	Fecal inoculum without the probiotic and prebiotic	555:604	Fecal inoculum without the probiotic and prebiotic was used as the control.					
36596205	5	59	theme	coordinate	641:650	arg1	PCoA					662:665	PCoA	662:665	PCoA	662:665	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	5	59	theme	coordinate	641:650	arg1	analysis					652:659	Principal coordinate analysis	631:659	Principal coordinate analysis (PCoA)	631:666	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	11	60	located	found	1758:1762	arg2	metabolites					1691:1701	Not all metabolites	1683:1701	Not all metabolites enriched in the probiotic and/or synbiotic groups	1683:1751	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	11	60	located	found	1758:1762	arg1	monocultures					1771:1782	the monocultures	1767:1782	the monocultures of the probiotic strain with or without the prebiotics	1767:1837	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	13	61	theme	microbiota	2105:2114	arg1	genus					2116:2120	the fecal microbiota genus	2095:2120	the fecal microbiota genus	2095:2120	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	9	62	theme	sub	1461:1463	arg1	cluster					1465:1471	a sub cluster	1459:1471	a sub cluster composed of metabolites enriched in the synbiotic group	1459:1527	A clustering based on 46 metabolites indicated that tryptophan-metabolites such as indole-3-lactic acid (ILA), indole-3-ethanol, and indole-3-carboxaldehyde, were included in a sub cluster composed of metabolites enriched in the synbiotic group.					
36596205	12	63	theme	fecal	1927:1931	arg1	microbiota					1933:1942	the fecal microbiota	1923:1942	the fecal microbiota	1923:1942	This implies that some of the metabolites were produced through the interaction of the fecal microbiota with the inoculated probiotic strain.					
36596205	8	64	theme	metabolites	1152:1162	arg1	metabolites					1152:1162	the 310 hydrophilic metabolites	1132:1162	the 310 hydrophilic metabolites	1132:1162	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	8	64	theme	metabolites	1152:1162	arg1	29					1126:1127	29	1126:1127	29	1126:1127	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	3	65	with	fermentation	382:393	arg1	lactulose					443:451	lactulose	443:451	lactulose (prebiotic)	443:463	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	65	with	fermentation	382:393	arg1	MCC1274					422:428	Bifidobacterium breve MCC1274	400:428	Bifidobacterium breve MCC1274 (probiotic)	400:440	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	65	with	fermentation	382:393	arg1	combination					471:481	a combination	469:481	a combination of both (synbiotic)	469:501	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	65	with	fermentation	382:393	arg1	prebiotic					454:462	prebiotic	454:462	prebiotic	454:462	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	11	66	theme	synbiotic	1736:1744	arg1	groups					1746:1751	the probiotic and/or synbiotic groups	1715:1751	the probiotic and/or synbiotic groups	1715:1751	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	2	67	theme	single-batch	307:318	arg1	fermenter					320:328	a pH-controlled single-batch fermenter	291:328	a pH-controlled single-batch fermenter	291:328	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	2	67	theme	single-batch	307:318	arg1	model					356:360	a human gut microbiota model	333:360	a human gut microbiota model	333:360	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	11	68	theme	probiotic	1719:1727	arg1	groups					1746:1751	the probiotic and/or synbiotic groups	1715:1751	the probiotic and/or synbiotic groups	1715:1751	Not all metabolites enriched in the probiotic and/or synbiotic groups were found in the monocultures of the probiotic strain with or without the prebiotics.					
36596205	13	69	theme	relative	2073:2080	arg1	abundance					2082:2090	the relative abundance	2069:2090	the relative abundance of the fecal microbiota genus	2069:2120	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	8	70	theme	lipophilic	1182:1191	arg1	metabolites					1193:1203	the 107 lipophilic metabolites	1174:1203	the 107 lipophilic metabolites	1174:1203	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	16	71	theme	signaling	2453:2461	arg1	molecules					2463:2471	signaling molecules	2453:2471	signaling molecules	2453:2471	In conclusion, synbiotics could enhance the production of signaling molecules in the gut environment.					
36596205	17	72	theme	effective	2538:2546	arg1	administration					2548:2561	more effective administration	2533:2561	more effective administration of probiotics at the molecular level	2533:2598	Our results provide an insight into more effective administration of probiotics at the molecular level.					
36596205	15	73	with	groups	2337:2342	arg1	probiotic					2353:2361	probiotic	2353:2361	probiotic	2353:2361	The copy number of ldh4 gene was significantly higher in the groups with the probiotic than that in the control group.					
36596205	1	74	from	microbiota	240:249	arg1	metabolites					215:225	metabolites	215:225	metabolites from the gut microbiota	215:249	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	7	75	theme	control	965:971	arg1	group					973:977	the control group	961:977	the control group	961:977	The relative abundance of Blautia was the highest in the control group among the four groups.					
36596205	2	76	theme	gut	341:343	arg1	fermenter					320:328	a pH-controlled single-batch fermenter	291:328	a pH-controlled single-batch fermenter	291:328	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	2	76	theme	gut	341:343	arg1	model					356:360	a human gut microbiota model	333:360	a human gut microbiota model	333:360	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	8	77	located	detected	1062:1069	arg1	group					1088:1092	the synbiotic group	1074:1092	the synbiotic group	1074:1092	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	8	77	located	detected	1062:1069	arg2	metabolites					1050:1060	metabolites	1050:1060	metabolites detected in the synbiotic group	1050:1092	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	0	78	theme	metabolites	92:102	arg1	production					67:76	production	67:76	production of tryptophan metabolites in fermented human fecal communities	67:139	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	1	79	theme	beneficial	173:182	arg1	effects					184:190	beneficial effects	173:190	beneficial effects on host physiology	173:209	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	3	80	from	influence	521:529	arg1	environment					542:552	the gut environment	534:552	the gut environment	534:552	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	0	81	theme	fermented	107:115	arg1	communities					129:139	fermented human fecal communities	107:139	fermented human fecal communities	107:139	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	1	82	from	effects	184:190	arg1	physiology					200:209	host physiology	195:209	host physiology	195:209	Probiotics and prebiotics have beneficial effects on host physiology via metabolites from the gut microbiota in addition to their own.					
36596205	2	83	theme	pH-controlled	293:305	arg1	fermenter					320:328	a pH-controlled single-batch fermenter	291:328	a pH-controlled single-batch fermenter	291:328	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	2	83	theme	pH-controlled	293:305	arg1	model					356:360	a human gut microbiota model	333:360	a human gut microbiota model	333:360	Here, we used a pH-controlled single-batch fermenter as a human gut microbiota model.					
36596205	8	84	dep	highest	1102:1108	arg1	352					1111:1113	352	1111:1113	352	1111:1113	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	0	85	theme	fecal	123:127	arg1	communities					129:139	fermented human fecal communities	107:139	fermented human fecal communities	107:139	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	3	86	dep	MCC1274	422:428	arg1	probiotic					431:439	probiotic	431:439	probiotic	431:439	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	5	87	theme	microbiota	701:710	arg1	composition					682:692	the composition	678:692	the composition of gut microbiota	678:710	Principal coordinate analysis (PCoA), based on the composition of gut microbiota, showed a significant difference among the groups.					
36596205	13	88	theme	networking	1995:2004	arg1	analysis					2006:2013	Co-abundance networking analysis	1982:2013	Co-abundance networking analysis	1982:2013	Co-abundance networking analysis indicated the differences in the correlations between the relative abundance of the fecal microbiota genus and the tryptophan metabolites in each group.					
36596205	8	89	from	groups	1249:1254	arg1	test					1278:1281	the Kruskal-Wallis test	1259:1281	the Kruskal-Wallis test	1259:1281	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	3	90	theme	Bifidobacterium	400:414	arg1	MCC1274					422:428	Bifidobacterium breve MCC1274	400:428	Bifidobacterium breve MCC1274 (probiotic)	400:440	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	10	91	dep	probiotic	1614:1622	arg1	enriched					1645:1652	enriched	1645:1652	was enriched only in the synbiotic group	1641:1680	Spermidine, a major polyamine, was enriched in the two groups supplemented with the probiotic whereas spermine was enriched only in the synbiotic group.					
36596205	14	92	theme	gene	2212:2215	arg1	abundance					2217:2225	ldh4 gene abundance	2207:2225	ldh4 gene abundance	2207:2225	There was a strong correlation between ldh4 gene abundance and ILA concentration in the fecal fermentation.					
36596205	0	93	theme	breve	30:34	arg1	MCC1274					36:42	Bifidobacterium breve MCC1274	14:42	Bifidobacterium breve MCC1274	14:42	Synbiotics of Bifidobacterium breve MCC1274 and lactulose enhances production of tryptophan metabolites in fermented human fecal communities.					
36596205	9	94	theme	synbiotic	1513:1521	arg1	group					1523:1527	the synbiotic group	1509:1527	the synbiotic group	1509:1527	A clustering based on 46 metabolites indicated that tryptophan-metabolites such as indole-3-lactic acid (ILA), indole-3-ethanol, and indole-3-carboxaldehyde, were included in a sub cluster composed of metabolites enriched in the synbiotic group.					
36596205	6	95	theme	synbiotic	837:845	arg1	group					847:851	the synbiotic group	833:851	the synbiotic group	833:851	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	3	96	theme	both	486:489	arg1	lactulose					443:451	lactulose	443:451	lactulose (prebiotic)	443:463	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	96	theme	both	486:489	arg1	MCC1274					422:428	Bifidobacterium breve MCC1274	400:428	Bifidobacterium breve MCC1274 (probiotic)	400:440	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	96	theme	both	486:489	arg1	combination					471:481	a combination	469:481	a combination of both (synbiotic)	469:501	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	3	96	theme	both	486:489	arg1	prebiotic					454:462	prebiotic	454:462	prebiotic	454:462	We conducted fecal fermentation with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to evaluate their influence on the gut environment.					
36596205	8	97	from	352	1111:1113	arg1	total					1118:1122	total	1118:1122	total	1118:1122	CE-TOFMS and LC-TOFMS showed that the number of metabolites detected in the synbiotic group was the highest (352 in total); 29 of the 310 hydrophilic metabolites and 17 of the 107 lipophilic metabolites were significantly different among the four groups in the Kruskal-Wallis test.					
36596205	6	98	theme	Bifidobacterium	789:803	arg1	higher					823:828	higher	823:828	higher	823:828	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36596205	6	98	theme	Bifidobacterium	789:803	arg1	abundance					776:784	The relative abundance	763:784	The relative abundance of Bifidobacterium	763:803	The relative abundance of Bifidobacterium was significantly higher in the synbiotic group, compared to that in the other three treatment groups.					
36478634	8	0	from	groups	1168:1173	arg1	S					1187:1187	ΔDi-(4,6)S	1178:1187	ΔDi-(4,6)S	1178:1187	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	4	1	theme	Disaccharide	586:597	arg1	analysis					611:618	Disaccharide composition analysis	586:618	Disaccharide composition analysis of digested products	586:639	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	7	2	theme	4,6	1120:1122	arg1	CSE-disaccharide					1097:1112	unsaturated CSE-disaccharide	1085:1112	unsaturated CSE-disaccharide	1085:1112	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	7	2	theme	4,6	1120:1122	arg1	S					1124:1124	ΔDi-(4,6)S	1115:1124	ΔDi-(4,6)S	1115:1124	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	11	3	theme	suggested	1782:1790	arg1	tendency					1876:1883	tendency	1876:1883	(b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1872:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	3	theme	suggested	1782:1790	arg1	resistance					1805:1814	resistance	1805:1814	(a) resistance of E-units in CSE molecules to digestion by cABC-I	1801:1865	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	3	theme	suggested	1782:1790	arg1	factors					1792:1798	two suggested factors	1778:1798	two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1778:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	7	4	from	cABC-I	1062:1067	arg1	complex					1072:1078	complex	1072:1078	complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S,	1072:1125	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	7	5	theme	ΔDi-	1115:1118	arg1	CSE-disaccharide					1097:1112	unsaturated CSE-disaccharide	1085:1112	unsaturated CSE-disaccharide	1085:1112	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	7	5	theme	ΔDi-	1115:1118	arg1	S					1124:1124	ΔDi-(4,6)S	1115:1124	ΔDi-(4,6)S	1115:1124	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	3	6	theme	structural	483:492	arg1	heterogeneity					494:506	structural heterogeneity	483:506	structural heterogeneity	483:506	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	1	7	theme	ABC	280:282	arg1	activity					295:302	chondroitinase ABC I (cABC-I) activity	265:302	chondroitinase ABC I (cABC-I) activity	265:302	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	8	8	theme	4-O-	1147:1150	arg1	groups					1168:1173	Both 4-O- and 6-O-sulfate groups	1142:1173	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S	1142:1187	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	7	9	from	crystallography	1043:1057	arg1	complex					1072:1078	complex	1072:1078	complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S,	1072:1125	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	3	10	theme	di-sulfated	517:527	arg1	units					542:546	di-sulfated disaccharide units	517:546	di-sulfated disaccharide units	517:546	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	8	11	theme	6-O-sulfate	1156:1166	arg1	groups					1168:1173	Both 4-O- and 6-O-sulfate groups	1142:1173	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S	1142:1187	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	4	12	from	units	682:686	arg1	CSE					691:693	CSE	691:693	CSE	691:693	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	11	13	theme	cABC-I	1926:1931	arg1	activity					1933:1940	cABC-I activity	1926:1940	cABC-I activity	1926:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	4	14	theme	mono-sulfated	655:667	arg1	units					682:686	mono-sulfated disaccharide units	655:686	mono-sulfated disaccharide units in CSE	655:693	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	0	15	theme	chondroitinase	129:142	arg1	activity					150:157	chondroitinase ABC I activity	129:157	chondroitinase ABC I activity	129:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	3	16	theme	mono-sulfated	552:564	arg1	units					579:583	mono-sulfated disaccharide units	552:583	mono-sulfated disaccharide units	552:583	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	0	17	from	moieties	92:99	arg1	E					124:124	chondroitin sulfate E	104:124	chondroitin sulfate E	104:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	11	18	theme	cABC-I	1743:1748	arg1	attributable					1762:1773	attributable	1762:1773	attributable	1762:1773	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	18	theme	cABC-I	1743:1748	arg1	reactivity					1729:1738	The low reactivity	1721:1738	The low reactivity of cABC-I with CSE	1721:1757	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	0	19	theme	I	148:148	arg1	activity					150:157	chondroitinase ABC I activity	129:157	chondroitinase ABC I activity	129:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	0	20	from	E	124:124	arg1	effect					52:57	the effect	48:57	the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity	48:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	2	21	contain	containing	400:409	arg1	CSE					396:398	CSE	396:398	CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)	396:455	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	21	contain	containing	400:409	arg2	4S,6S					450:454	4S,6S	450:454	4S,6S	450:454	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	21	contain	containing	400:409	arg2	[GalNAc					442:448	4,6-O-disulfated GalNAc [GalNAc	418:448	4,6-O-disulfated GalNAc [GalNAc(4S,6S)	418:455	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	1	22	from	residues	205:212	arg1	sulfate					229:235	chondroitin sulfate	217:235	chondroitin sulfate (CS)	217:240	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	1	22	from	residues	205:212	arg1	CS					238:239	CS	238:239	CS	238:239	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	8	23	theme	ΔDi-	1267:1270	arg1	S					1276:1276	ΔDi-(4,6)S	1267:1276	ΔDi-(4,6)S	1267:1276	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	0	24	theme	4,6-O-disulfated	62:77	arg1	moieties					92:99	4,6-O-disulfated disaccharide moieties	62:99	4,6-O-disulfated disaccharide moieties in chondroitin sulfate E	62:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	5	25	from	amount	862:867	arg1	mixture					883:889	the mixture	879:889	the mixture	879:889	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	9	26	theme	charge	1450:1455	arg1	Arg500					1429:1434	Arg500	1429:1434	Arg500	1429:1434	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	26	theme	charge	1450:1455	arg1	neutralization					1457:1470	the charge neutralization	1446:1470	the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS	1446:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	27	from	group	1487:1491	arg1	CS					1533:1534	CS	1533:1534	CS	1533:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	11	28	theme	CSE	1899:1901	arg1	molecules					1903:1911	CSE molecules	1899:1911	CSE molecules	1899:1911	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	8	29	theme	4,6	1272:1274	arg1	S					1276:1276	ΔDi-(4,6)S	1267:1276	ΔDi-(4,6)S	1267:1276	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	0	30	theme	moieties	92:99	arg1	effect					52:57	the effect	48:57	the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity	48:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	11	31	with	reactivity	1729:1738	arg1	CSE					1755:1757	CSE	1755:1757	CSE	1755:1757	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	6	32	theme	enzyme	987:992	arg1	activity					994:1001	enzyme activity	987:1001	enzyme activity	987:1001	These results suggested that CSE is not only resistant to enzyme digestion but also attenuates enzyme activity.					
36478634	0	33	theme	chondroitin	104:114	arg1	E					124:124	chondroitin sulfate E	104:124	chondroitin sulfate E	104:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	9	34	theme	carboxy	1479:1485	arg1	group					1487:1491	the carboxy group	1475:1491	the carboxy group of D-glucuronic acid (GlcA) residues in CS	1475:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	34	theme	carboxy	1479:1485	arg1	residues					1521:1528	D-glucuronic acid (GlcA) residues	1496:1528	D-glucuronic acid (GlcA) residues in CS	1496:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	0	35	from	effect	52:57	arg1	activity					150:157	chondroitinase ABC I activity	129:157	chondroitinase ABC I activity	129:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	0	35	from	effect	52:57	arg1	E					124:124	chondroitin sulfate E	104:124	chondroitin sulfate E	104:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	10	36	theme	CSE-disaccharide	1563:1578	arg1	4S,6S					1601:1605	4S,6S	1601:1605	4S,6S	1601:1605	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	10	36	theme	CSE-disaccharide	1563:1578	arg1	[GlcAβ1-3GalNAc					1585:1599	the CSE-disaccharide unit [GlcAβ1-3GalNAc	1559:1599	the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS	1559:1613	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	0	37	theme	Biochemical	0:10	arg1	assessments					33:43	Biochemical and crystallographic assessments	0:43	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.	0:158	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	9	38	theme	acid	1509:1512	arg1	residues					1521:1528	D-glucuronic acid (GlcA) residues	1496:1528	D-glucuronic acid (GlcA) residues in CS	1496:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	2	39	theme	GalNAc	435:440	arg1	[GalNAc					442:448	4,6-O-disulfated GalNAc [GalNAc	418:448	4,6-O-disulfated GalNAc [GalNAc(4S,6S)	418:455	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	39	theme	GalNAc	435:440	arg1	4S,6S					450:454	4S,6S	450:454	4S,6S	450:454	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	0	40	theme	crystallographic	16:31	arg1	assessments					33:43	Biochemical and crystallographic assessments	0:43	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.	0:158	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	4	41	theme	enzyme	714:719	arg1	reactivity					721:730	the enzyme reactivity	710:730	the enzyme reactivity	710:730	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	9	42	theme	enzyme	1379:1384	arg1	activity					1386:1393	enzyme activity	1379:1393	enzyme activity	1379:1393	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	5	43	theme	CSE	800:802	arg1	mixtures					780:787	mixtures	780:787	mixtures of CSA and CSE	780:802	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	9	44	theme	residues	1521:1528	arg1	group					1487:1491	the carboxy group	1475:1491	the carboxy group of D-glucuronic acid (GlcA) residues in CS	1475:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	44	theme	residues	1521:1528	arg1	residues					1521:1528	D-glucuronic acid (GlcA) residues	1496:1528	D-glucuronic acid (GlcA) residues in CS	1496:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	3	45	contain	has	513:515	arg2	units					579:583	mono-sulfated disaccharide units	552:583	mono-sulfated disaccharide units	552:583	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	3	45	contain	has	513:515	arg2	units					542:546	di-sulfated disaccharide units	517:546	di-sulfated disaccharide units	517:546	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	3	45	contain	has	513:515	arg1	CSE					509:511	CSE	509:511	CSE	509:511	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	0	46	theme	effect	52:57	arg1	assessments					33:43	Biochemical and crystallographic assessments	0:43	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.	0:158	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	11	47	dep	resistance	1805:1814	arg1	a					1802:1802	a	1802:1802	a	1802:1802	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	10	48	from	[GlcAβ1-3GalNAc	1585:1599	arg1	CS					1612:1613	CS	1612:1613	CS	1612:1613	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	11	49	from	E-units	1888:1894	arg1	molecules					1903:1911	CSE molecules	1899:1911	CSE molecules	1899:1911	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	2	50	theme	4-O-monosulfated	327:342	arg1	GalNAc					344:349	mainly 4-O-monosulfated GalNAc	320:349	mainly 4-O-monosulfated GalNAc	320:349	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	5	51	located	present	769:775	arg1	mixtures					780:787	mixtures	780:787	mixtures of CSA and CSE	780:802	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	5	51	located	present	769:775	arg2	substrate					749:757	enough substrate	742:757	enough substrate (CSA)	742:763	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	5	51	located	present	769:775	arg2	CSA					760:762	CSA	760:762	CSA	760:762	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	10	52	theme	CS-disaccharide	1650:1664	arg1	units					1666:1670	other CS-disaccharide units	1644:1670	other CS-disaccharide units	1644:1670	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	1	53	theme	O-sulfated	160:169	arg1	residues					205:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues	160:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS)	160:240	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	10	54	theme	other	1644:1648	arg1	units					1666:1670	other CS-disaccharide units	1644:1670	other CS-disaccharide units	1644:1670	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	4	55	theme	products	632:639	arg1	analysis					611:618	Disaccharide composition analysis	586:618	Disaccharide composition analysis of digested products	586:639	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	2	56	theme	good	357:360	arg1	CSA					305:307	CSA	305:307	CSA containing mainly 4-O-monosulfated GalNAc	305:349	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	56	theme	good	357:360	arg1	substrate					362:370	a good substrate	355:370	a good substrate for the enzyme	355:385	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	11	57	from	tendency	1876:1883	arg1	molecules					1834:1842	CSE molecules	1830:1842	CSE molecules	1830:1842	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	57	from	tendency	1876:1883	arg1	molecules					1903:1911	CSE molecules	1899:1911	CSE molecules	1899:1911	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	3	58	theme	disaccharide	529:540	arg1	units					542:546	di-sulfated disaccharide units	517:546	di-sulfated disaccharide units	517:546	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	11	59	from	resistance	1805:1814	arg1	molecules					1834:1842	CSE molecules	1830:1842	CSE molecules	1830:1842	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	59	from	resistance	1805:1814	arg1	molecules					1903:1911	CSE molecules	1899:1911	CSE molecules	1899:1911	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	1	60	theme	chondroitinase	265:278	arg1	cABC-I					287:292	cABC-I	287:292	cABC-I	287:292	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	1	60	theme	chondroitinase	265:278	arg1	ABC					280:282	chondroitinase ABC I	265:284	chondroitinase ABC I (cABC-I) activity	265:302	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	10	61	theme	CSE-disaccharide	1698:1713	arg1	unit					1715:1718	the CSE-disaccharide unit	1694:1718	the CSE-disaccharide unit	1694:1718	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	4	62	theme	composition	599:609	arg1	analysis					611:618	Disaccharide composition analysis	586:618	Disaccharide composition analysis of digested products	586:639	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	7	63	theme	unsaturated	1085:1095	arg1	CSE-disaccharide					1097:1112	unsaturated CSE-disaccharide	1085:1112	unsaturated CSE-disaccharide	1085:1112	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	7	63	theme	unsaturated	1085:1095	arg1	S					1124:1124	ΔDi-(4,6)S	1115:1124	ΔDi-(4,6)S	1115:1124	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	1	64	theme	GalNAc	197:202	arg1	residues					205:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues	160:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS)	160:240	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	5	65	theme	CSA	792:794	arg1	mixtures					780:787	mixtures	780:787	mixtures of CSA and CSE	780:802	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	3	66	theme	disaccharide	566:577	arg1	units					579:583	mono-sulfated disaccharide units	552:583	mono-sulfated disaccharide units	552:583	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	5	67	theme	CSE	872:874	arg1	CSE					872:874	CSE	872:874	CSE	872:874	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	5	67	theme	CSE	872:874	arg1	amount					862:867	the amount	858:867	the amount of CSE in the mixture	858:889	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	11	68	theme	low	1725:1727	arg1	attributable					1762:1773	attributable	1762:1773	attributable	1762:1773	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	68	theme	low	1725:1727	arg1	reactivity					1729:1738	The low reactivity	1721:1738	The low reactivity of cABC-I with CSE	1721:1757	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	0	69	theme	ABC	144:146	arg1	activity					150:157	chondroitinase ABC I activity	129:157	chondroitinase ABC I activity	129:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	11	70	theme	E-units	1888:1894	arg1	tendency					1876:1883	tendency	1876:1883	(b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1872:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	70	theme	E-units	1888:1894	arg1	resistance					1805:1814	resistance	1805:1814	(a) resistance of E-units in CSE molecules to digestion by cABC-I	1801:1865	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	70	theme	E-units	1888:1894	arg1	factors					1792:1798	two suggested factors	1778:1798	two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1778:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	1	71	theme	chondroitin	217:227	arg1	sulfate					229:235	chondroitin sulfate	217:235	chondroitin sulfate (CS)	217:240	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	1	71	theme	chondroitin	217:227	arg1	CS					238:239	CS	238:239	CS	238:239	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	6	72	theme	enzyme	950:955	arg1	digestion					957:965	enzyme digestion	950:965	enzyme digestion	950:965	These results suggested that CSE is not only resistant to enzyme digestion but also attenuates enzyme activity.					
36478634	5	73	from	present	769:775	arg1	mixtures					780:787	mixtures	780:787	mixtures of CSA and CSE	780:802	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	8	74	theme	ΔDi-	1178:1181	arg1	S					1187:1187	ΔDi-(4,6)S	1178:1187	ΔDi-(4,6)S	1178:1187	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	4	75	theme	disaccharide	669:680	arg1	units					682:686	mono-sulfated disaccharide units	655:686	mono-sulfated disaccharide units in CSE	655:693	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	7	76	theme	action	1035:1040	arg1	mechanism					1022:1030	the mechanism	1018:1030	the mechanism of action	1018:1040	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	9	77	theme	Arg500	1429:1434	arg1	function					1417:1424	a function	1415:1424	a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS	1415:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	8	78	theme	4,6	1183:1185	arg1	S					1187:1187	ΔDi-(4,6)S	1178:1187	ΔDi-(4,6)S	1178:1187	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	7	79	theme	cABC-I	1062:1067	arg1	crystallography					1043:1057	crystallography	1043:1057	crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S,	1043:1125	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	11	80	dep	tendency	1876:1883	arg1	b					1873:1873	b	1873:1873	b	1873:1873	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	8	81	theme	greater	1239:1245	arg1	interaction					1247:1257	a greater interaction	1237:1257	a greater interaction between ΔDi-(4,6)S and Arg500	1237:1287	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	0	82	theme	disaccharide	79:90	arg1	moieties					92:99	4,6-O-disulfated disaccharide moieties	62:99	4,6-O-disulfated disaccharide moieties in chondroitin sulfate E	62:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	5	83	from	mixtures	780:787	arg1	present					769:775	present	769:775	present	769:775	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	0	84	from	assessments	33:43	arg1	activity					150:157	chondroitinase ABC I activity	129:157	chondroitinase ABC I activity	129:157	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	0	85	from	activity	150:157	arg1	assessments					33:43	Biochemical and crystallographic assessments	0:43	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.	0:158	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	1	86	theme	N-acetyl-d-galactosamine	171:194	arg1	residues					205:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues	160:212	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS)	160:240	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36478634	0	87	theme	sulfate	116:122	arg1	E					124:124	chondroitin sulfate E	104:124	chondroitin sulfate E	104:124	Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.					
36478634	9	88	theme	group	1487:1491	arg1	Arg500					1429:1434	Arg500	1429:1434	Arg500	1429:1434	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	88	theme	group	1487:1491	arg1	neutralization					1457:1470	the charge neutralization	1446:1470	the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS	1446:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	10	89	theme	unit	1580:1583	arg1	4S,6S					1601:1605	4S,6S	1601:1605	4S,6S	1601:1605	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	10	89	theme	unit	1580:1583	arg1	[GlcAβ1-3GalNAc					1585:1599	the CSE-disaccharide unit [GlcAβ1-3GalNAc	1559:1599	the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS	1559:1613	When interacting with the CSE-disaccharide unit [GlcAβ1-3GalNAc(4S,6S)] in CS, cABC-I cannot interact with other CS-disaccharide units until it has digested the CSE-disaccharide unit.					
36478634	9	90	theme	D-glucuronic	1496:1507	arg1	acid					1509:1512	D-glucuronic acid	1496:1512	D-glucuronic acid (GlcA) residues in CS	1496:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	90	theme	D-glucuronic	1496:1507	arg1	GlcA					1515:1518	GlcA	1515:1518	GlcA	1515:1518	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	7	91	from	complex	1072:1078	arg1	crystallography					1043:1057	crystallography	1043:1057	crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S,	1043:1125	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	11	92	dep	factors	1792:1798	arg1	tendency					1876:1883	tendency	1876:1883	(b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1872:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	92	dep	factors	1792:1798	arg1	resistance					1805:1814	resistance	1805:1814	(a) resistance of E-units in CSE molecules to digestion by cABC-I	1801:1865	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	92	dep	factors	1792:1798	arg1	factors					1792:1798	two suggested factors	1778:1798	two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1778:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	9	93	from	CS	1533:1534	arg1	group					1487:1491	the carboxy group	1475:1491	the carboxy group of D-glucuronic acid (GlcA) residues in CS	1475:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	9	93	from	CS	1533:1534	arg1	residues					1521:1528	D-glucuronic acid (GlcA) residues	1496:1528	D-glucuronic acid (GlcA) residues in CS	1496:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	2	94	theme	4,6-O-disulfated	418:433	arg1	[GalNAc					442:448	4,6-O-disulfated GalNAc [GalNAc	418:448	4,6-O-disulfated GalNAc [GalNAc(4S,6S)	418:455	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	94	theme	4,6-O-disulfated	418:433	arg1	4S,6S					450:454	4S,6S	450:454	4S,6S	450:454	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	8	95	theme	mono-sulfated	1302:1314	arg1	disaccharides					1316:1328	mono-sulfated disaccharides	1302:1328	mono-sulfated disaccharides	1302:1328	Both 4-O- and 6-O-sulfate groups in ΔDi-(4,6)S interact with Arg500, suggesting that there was a greater interaction between ΔDi-(4,6)S and Arg500 than between mono-sulfated disaccharides and Arg500.					
36478634	11	96	theme	CSE	1830:1832	arg1	molecules					1834:1842	CSE molecules	1830:1842	CSE molecules	1830:1842	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	9	97	from	residues	1521:1528	arg1	CS					1533:1534	CS	1533:1534	CS	1533:1534	Besides, this interaction attenuated enzyme activity by interfering with a function of Arg500, which is the charge neutralization of the carboxy group of D-glucuronic acid (GlcA) residues in CS.					
36478634	11	98	theme	E-units	1819:1825	arg1	tendency					1876:1883	tendency	1876:1883	(b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1872:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	98	theme	E-units	1819:1825	arg1	resistance					1805:1814	resistance	1805:1814	(a) resistance of E-units in CSE molecules to digestion by cABC-I	1801:1865	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	98	theme	E-units	1819:1825	arg1	factors					1792:1798	two suggested factors	1778:1798	two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1778:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	7	99	with	complex	1072:1078	arg1	CSE-disaccharide					1097:1112	unsaturated CSE-disaccharide	1085:1112	unsaturated CSE-disaccharide	1085:1112	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	7	99	with	complex	1072:1078	arg1	S					1124:1124	ΔDi-(4,6)S	1115:1124	ΔDi-(4,6)S	1115:1124	To understand the mechanism of action, crystallography of cABC-I in complex with unsaturated CSE-disaccharide, ΔDi-(4,6)S, was performed.					
36478634	2	100	contain	containing	309:318	arg1	substrate					362:370	a good substrate	355:370	a good substrate for the enzyme	355:385	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	100	contain	containing	309:318	arg1	CSA					305:307	CSA	305:307	CSA containing mainly 4-O-monosulfated GalNAc	305:349	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	2	100	contain	containing	309:318	arg2	GalNAc					344:349	mainly 4-O-monosulfated GalNAc	320:349	mainly 4-O-monosulfated GalNAc	320:349	CSA containing mainly 4-O-monosulfated GalNAc was a good substrate for the enzyme, but not CSE containing mainly 4,6-O-disulfated GalNAc [GalNAc(4S,6S)].					
36478634	4	101	theme	digested	623:630	arg1	products					632:639	digested products	623:639	digested products	623:639	Disaccharide composition analysis of digested products revealed that mono-sulfated disaccharide units in CSE contributed to the enzyme reactivity.					
36478634	3	102	theme	CS	464:465	arg1	isomer					467:472	Each CS isomer	459:472	Each CS isomer	459:472	Each CS isomer exhibits structural heterogeneity; CSE has di-sulfated disaccharide units and mono-sulfated disaccharide units.					
36478634	11	103	from	molecules	1903:1911	arg1	tendency					1876:1883	tendency	1876:1883	(b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1872:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	103	from	molecules	1903:1911	arg1	resistance					1805:1814	resistance	1805:1814	(a) resistance of E-units in CSE molecules to digestion by cABC-I	1801:1865	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	11	103	from	molecules	1903:1911	arg1	factors					1792:1798	two suggested factors	1778:1798	two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity	1778:1940	The low reactivity of cABC-I with CSE is attributable to two suggested factors: (a) resistance of E-units in CSE molecules to digestion by cABC-I, and (b) tendency of E-units in CSE molecules to attenuate cABC-I activity.					
36478634	5	104	attach	present	769:775	arg1	mixtures					780:787	mixtures	780:787	mixtures of CSA and CSE	780:802	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	5	104	attach	present	769:775	arg2	substrate					749:757	enough substrate	742:757	enough substrate (CSA)	742:763	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	5	104	attach	present	769:775	arg2	CSA					760:762	CSA	760:762	CSA	760:762	Although enough substrate (CSA) was present in mixtures of CSA and CSE for reaction, the reactivity was reduced depending on the amount of CSE in the mixture.					
36478634	1	105	theme	crucial	249:255	arg1	role					257:260	a crucial role	247:260	a crucial role	247:260	O-sulfated N-acetyl-d-galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC-I) activity.					
36709843	6	0	theme	atomic	905:910	arg1	analysis					923:930	flame atomic absorption analysis	899:930	flame atomic absorption analysis	899:930	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	1	1	theme	cellulose	186:194	arg1	composite					163:171	an original catalytic composite	141:171	an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	141:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	1	theme	cellulose	186:194	arg1	cellulose					186:194	bacterial cellulose	176:194	bacterial cellulose (BC)	176:199	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	1	theme	cellulose	186:194	arg1	pyrite					205:210	pyrite	205:210	pyrite (FeS2)	205:217	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	9	2	theme	%	1292:1292	arg1	degradations					1261:1272	degradations	1261:1272	degradations of 52.87 and 96.82%, respectively	1261:1306	The composite acted as the catalyst for the Fenton and photo-Fenton processes, with degradations of 52.87 and 96.82%, respectively.					
36709843	0	3	theme	oxidation	101:109	arg1	processes					111:119	advanced oxidation processes	92:119	advanced oxidation processes	92:119	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	6	4	theme	flame	899:903	arg1	analysis					923:930	flame atomic absorption analysis	899:930	flame atomic absorption analysis	899:930	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	4	5	from	immobilization	569:582	arg1	biopolymer					613:622	the biopolymer	609:622	the biopolymer	609:622	Thus, the immobilization of the iron particles on the biopolymer was proven, producing the composite BC/FeS2.					
36709843	11	6	theme	metal	1525:1529	arg1	concentration					1503:1515	the remaining concentration	1489:1515	the remaining concentration of this metal in the BC	1489:1539	Thus, its high potential for reuse is presumed, given the remaining concentration of this metal in the BC.					
36709843	12	7	theme	suspension	1657:1666	arg1	form					1668:1671	suspension form	1657:1671	suspension form	1657:1671	The results showed that the BC/FeS2 composite is suitable to solve the problems associated with using catalysts in suspension form.					
36709843	8	8	theme	advanced	1147:1154	arg1	processes					1166:1174	advanced oxidative processes	1147:1174	advanced oxidative processes	1147:1174	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	10	9	theme	iron	1354:1357	arg1	leaching					1359:1366	low iron leaching	1350:1366	low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes)	1350:1432	The material proved stability by showing low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes).					
36709843	0	10	from	application	77:87	arg1	processes					111:119	advanced oxidation processes	92:119	advanced oxidation processes	92:119	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	1	11	theme	study	275:279	arg1	development					126:136	The development	122:136	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	122:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	11	theme	study	275:279	arg1	objective					257:265	the objective	253:265	the objective of this study	253:279	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	5	12	theme	FeS2	815:818	arg1	particles					820:828	FeS2 particles	815:828	FeS2 particles	815:828	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	3	13	theme	FTIR	432:435	arg1	analyzes					445:452	the FTIR and XRD analyzes	428:452	analyzes	445:452	In the BC, the FTIR and XRD analyzes showed the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite.					
36709843	8	14	used	used	1110:1113	arg2	solution					1081:1088	A multi-component solution	1063:1088	A multi-component solution of textile dyes	1063:1104	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	8	14	used	used	1110:1113	arg2	matrix					1122:1127	the matrix	1118:1127	the matrix	1118:1127	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	7	15	theme	TG	933:934	arg1	analysis					936:943	TG analysis	933:943	TG analysis	933:943	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	3	16	theme	crystalline	515:525	arg1	peaks					527:531	the Fe-S bond and crystalline peaks	497:531	peaks	527:531	In the BC, the FTIR and XRD analyzes showed the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite.					
36709843	2	17	theme	ex	396:397	arg1	methodology					404:414	ex situ methodology	396:414	ex situ methodology	396:414	Nanoparticles of the FeS2 were synthesized from the hydrothermal method and immobilized on the BC structure using ex situ methodology.					
36709843	0	18	theme	nanostructured	9:22	arg1	composite					51:59	Original nanostructured bacterial cellulose/pyrite composite	0:59	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	8	19	theme	multi-component	1065:1079	arg1	solution					1081:1088	A multi-component solution	1063:1088	A multi-component solution of textile dyes	1063:1104	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	8	19	theme	multi-component	1065:1079	arg1	matrix					1122:1127	the matrix	1118:1127	the matrix	1118:1127	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	5	20	theme	composite	716:724	arg1	production					726:735	the composite production	712:735	the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles	712:828	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	10	21	dep	leaching	1359:1366	arg1	2.02 ± 0.09					1369:1379	2.02 ± 0.09	1369:1379	2.02 ± 0.09	1369:1379	The material proved stability by showing low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes).					
36709843	10	21	dep	leaching	1359:1366	arg1	2.11 ± 0.11 mg L-1					1385:1402	2.11 ± 0.11 mg L-1	1385:1402	2.11 ± 0.11 mg L-1	1385:1402	The material proved stability by showing low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes).					
36709843	0	22	theme	Original	0:7	arg1	composite					51:59	Original nanostructured bacterial cellulose/pyrite composite	0:59	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	12	23	theme	BC/FeS2	1570:1576	arg1	suitable					1591:1598	suitable	1591:1598	suitable	1591:1598	The results showed that the BC/FeS2 composite is suitable to solve the problems associated with using catalysts in suspension form.					
36709843	12	23	theme	BC/FeS2	1570:1576	arg1	composite					1578:1586	the BC/FeS2 composite	1566:1586	the BC/FeS2 composite	1566:1586	The results showed that the BC/FeS2 composite is suitable to solve the problems associated with using catalysts in suspension form.					
36709843	11	24	from	concentration	1503:1515	arg1	BC					1538:1539	the BC	1534:1539	the BC	1534:1539	Thus, its high potential for reuse is presumed, given the remaining concentration of this metal in the BC.					
36709843	11	25	theme	high	1445:1448	arg1	potential					1450:1458	its high potential	1441:1458	its high potential for reuse	1441:1468	Thus, its high potential for reuse is presumed, given the remaining concentration of this metal in the BC.					
36709843	1	26	theme	pyrite	205:210	arg1	composite					163:171	an original catalytic composite	141:171	an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	141:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	26	theme	pyrite	205:210	arg1	cellulose					186:194	bacterial cellulose	176:194	bacterial cellulose (BC)	176:199	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	26	theme	pyrite	205:210	arg1	pyrite					205:210	pyrite	205:210	pyrite (FeS2)	205:217	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	0	27	theme	cellulose/pyrite	34:49	arg1	composite					51:59	Original nanostructured bacterial cellulose/pyrite composite	0:59	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	8	28	theme	oxidative	1156:1164	arg1	processes					1166:1174	advanced oxidative processes	1147:1174	advanced oxidative processes	1147:1174	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	7	29	theme	degradation	949:959	arg1	tests					961:965	degradation tests	949:965	degradation tests	949:965	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	9	30	theme	Fenton	1221:1226	arg1	processes					1245:1253	the Fenton and photo-Fenton processes	1217:1253	processes	1245:1253	The composite acted as the catalyst for the Fenton and photo-Fenton processes, with degradations of 52.87 and 96.82%, respectively.					
36709843	0	31	theme	bacterial	24:32	arg1	composite					51:59	Original nanostructured bacterial cellulose/pyrite composite	0:59	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	11	32	theme	remaining	1493:1501	arg1	concentration					1503:1515	the remaining concentration	1489:1515	the remaining concentration of this metal in the BC	1489:1539	Thus, its high potential for reuse is presumed, given the remaining concentration of this metal in the BC.					
36709843	2	33	theme	FeS2	303:306	arg1	Nanoparticles					282:294	Nanoparticles	282:294	Nanoparticles of the FeS2	282:306	Nanoparticles of the FeS2 were synthesized from the hydrothermal method and immobilized on the BC structure using ex situ methodology.					
36709843	3	34	theme	Fe-S	501:504	arg1	bond					506:509	the Fe-S bond and crystalline peaks	497:531	bond	506:509	In the BC, the FTIR and XRD analyzes showed the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite.					
36709843	7	35	theme	potential	1052:1060	arg1	stability					999:1007	the thermal stability	987:1007	the thermal stability of the new material and its high catalytic potential	987:1060	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	6	36	theme	iron	841:844	arg1	54.76 ± 1.69 mg L-1					864:882	54.76 ± 1.69 mg L-1	864:882	54.76 ± 1.69 mg L-1	864:882	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	6	36	theme	iron	841:844	arg1	concentration					846:858	The total iron concentration	831:858	The total iron concentration	831:858	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	5	37	theme	fibrillar	756:764	arg1	morphology					776:785	the fibrillar structure morphology	752:785	the fibrillar structure morphology of the cellulose covered by FeS2 particles	752:828	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	5	38	theme	SEM	684:686	arg1	technique					688:696	the SEM technique	680:696	the SEM technique	680:696	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	6	39	theme	total	835:839	arg1	54.76 ± 1.69 mg L-1					864:882	54.76 ± 1.69 mg L-1	864:882	54.76 ± 1.69 mg L-1	864:882	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	6	39	theme	total	835:839	arg1	concentration					846:858	The total iron concentration	831:858	The total iron concentration	831:858	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	5	40	theme	cellulose	794:802	arg1	morphology					776:785	the fibrillar structure morphology	752:785	the fibrillar structure morphology of the cellulose covered by FeS2 particles	752:828	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	7	41	theme	new	1016:1018	arg1	material					1020:1027	the new material	1012:1027	the new material	1012:1027	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	3	42	theme	XRD	441:443	arg1	analyzes					445:452	the FTIR and XRD analyzes	428:452	analyzes	445:452	In the BC, the FTIR and XRD analyzes showed the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite.					
36709843	5	43	theme	structure	766:774	arg1	morphology					776:785	the fibrillar structure morphology	752:785	the fibrillar structure morphology of the cellulose covered by FeS2 particles	752:828	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	5	44	theme	technique	688:696	arg1	use					673:675	The use	669:675	The use of the SEM technique	669:696	The use of the SEM technique also ratifies the composite production by identifying the fibrillar structure morphology of the cellulose covered by FeS2 particles.					
36709843	7	45	theme	high	1037:1040	arg1	potential					1052:1060	its high catalytic potential	1033:1060	its high catalytic potential	1033:1060	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	9	46	theme	photo-Fenton	1232:1243	arg1	processes					1245:1253	the Fenton and photo-Fenton processes	1217:1253	processes	1245:1253	The composite acted as the catalyst for the Fenton and photo-Fenton processes, with degradations of 52.87 and 96.82%, respectively.					
36709843	7	47	theme	material	1020:1027	arg1	stability					999:1007	the thermal stability	987:1007	the thermal stability of the new material and its high catalytic potential	987:1060	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	0	48	theme	Photocatalytic	62:75	arg1	application					77:87	Photocatalytic application	62:87	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	7	49	theme	catalytic	1042:1050	arg1	potential					1052:1060	its high catalytic potential	1033:1060	its high catalytic potential	1033:1060	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	0	50	dep	composite	51:59	arg1	application					77:87	Photocatalytic application	62:87	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.	0:120	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	1	51	theme	original	144:151	arg1	composite					163:171	an original catalytic composite	141:171	an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	141:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	51	theme	original	144:151	arg1	cellulose					186:194	bacterial cellulose	176:194	bacterial cellulose (BC)	176:199	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	51	theme	original	144:151	arg1	pyrite					205:210	pyrite	205:210	pyrite (FeS2)	205:217	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	8	52	theme	dyes	1101:1104	arg1	solution					1081:1088	A multi-component solution	1063:1088	A multi-component solution of textile dyes	1063:1104	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	8	52	theme	dyes	1101:1104	arg1	matrix					1122:1127	the matrix	1118:1127	the matrix	1118:1127	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	10	53	theme	respective	1412:1421	arg1	processes					1423:1431	the respective processes	1408:1431	the respective processes	1408:1431	The material proved stability by showing low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes).					
36709843	4	54	theme	composite	650:658	arg1	BC/FeS2					660:666	the composite BC/FeS2	646:666	the composite BC/FeS2	646:666	Thus, the immobilization of the iron particles on the biopolymer was proven, producing the composite BC/FeS2.					
36709843	1	55	theme	catalytic	153:161	arg1	composite					163:171	an original catalytic composite	141:171	an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	141:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	55	theme	catalytic	153:161	arg1	cellulose					186:194	bacterial cellulose	176:194	bacterial cellulose (BC)	176:199	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	55	theme	catalytic	153:161	arg1	pyrite					205:210	pyrite	205:210	pyrite (FeS2)	205:217	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	56	theme	environmental	223:235	arg1	application					237:247	environmental application	223:247	environmental application	223:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	7	57	theme	thermal	991:997	arg1	stability					999:1007	the thermal stability	987:1007	the thermal stability of the new material and its high catalytic potential	987:1060	TG analysis and degradation tests showed respectively the thermal stability of the new material and its high catalytic potential.					
36709843	1	58	theme	composite	163:171	arg1	development					126:136	The development	122:136	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application	122:247	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	58	theme	composite	163:171	arg1	objective					257:265	the objective	253:265	the objective of this study	253:279	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	2	59	theme	hydrothermal	334:345	arg1	method					347:352	the hydrothermal method	330:352	the hydrothermal method	330:352	Nanoparticles of the FeS2 were synthesized from the hydrothermal method and immobilized on the BC structure using ex situ methodology.					
36709843	0	60	theme	advanced	92:99	arg1	processes					111:119	advanced oxidation processes	92:119	advanced oxidation processes	92:119	Original nanostructured bacterial cellulose/pyrite composite: Photocatalytic application in advanced oxidation processes.					
36709843	10	61	theme	low	1350:1352	arg1	leaching					1359:1366	low iron leaching	1350:1366	low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes)	1350:1432	The material proved stability by showing low iron leaching (2.02 ± 0.09 and 2.11 ± 0.11 mg L-1 for the respective processes).					
36709843	2	62	theme	BC	377:378	arg1	structure					380:388	the BC structure	373:388	the BC structure using ex situ methodology	373:414	Nanoparticles of the FeS2 were synthesized from the hydrothermal method and immobilized on the BC structure using ex situ methodology.					
36709843	3	63	theme	absorption	465:474	arg1	band					476:479	the absorption band	461:479	the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite	461:556	In the BC, the FTIR and XRD analyzes showed the absorption band associated with the Fe-S bond and crystalline peaks attributed to the pyrite.					
36709843	4	64	theme	particles	596:604	arg1	immobilization					569:582	the immobilization	565:582	the immobilization of the iron particles on the biopolymer	565:622	Thus, the immobilization of the iron particles on the biopolymer was proven, producing the composite BC/FeS2.					
36709843	6	65	theme	absorption	912:921	arg1	analysis					923:930	flame atomic absorption analysis	899:930	flame atomic absorption analysis	899:930	The total iron concentration was 54.76 ± 1.69 mg L-1, determined by flame atomic absorption analysis.					
36709843	2	66	dep	ex	396:397	arg1	situ					399:402	situ	399:402	situ	399:402	Nanoparticles of the FeS2 were synthesized from the hydrothermal method and immobilized on the BC structure using ex situ methodology.					
36709843	1	67	theme	bacterial	176:184	arg1	BC					197:198	BC	197:198	BC	197:198	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	1	67	theme	bacterial	176:184	arg1	cellulose					186:194	bacterial cellulose	176:194	bacterial cellulose (BC)	176:199	The development of an original catalytic composite of bacterial cellulose (BC) and pyrite (FeS2) for environmental application was the objective of this study.					
36709843	8	68	theme	textile	1093:1099	arg1	dyes					1101:1104	textile dyes	1093:1104	textile dyes	1093:1104	A multi-component solution of textile dyes was used as the matrix to be treated via advanced oxidative processes.					
36709843	4	69	theme	iron	591:594	arg1	particles					596:604	the iron particles	587:604	the iron particles	587:604	Thus, the immobilization of the iron particles on the biopolymer was proven, producing the composite BC/FeS2.					
35884266	2	0	theme	electrochemical	388:402	arg1	nano-biosensor					404:417	an electrochemical nano-biosensor	385:417	an electrochemical nano-biosensor	385:417	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	5	1	theme	GO/Co/chitosan	1052:1065	arg1	composite					1067:1075	the GO/Co/chitosan composite	1048:1075	the GO/Co/chitosan composite	1048:1075	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	7	2	theme	detected	1350:1357	arg1	concentrations					1359:1372	detected concentrations	1350:1372	detected concentrations from 1.0 to 15.0 mM	1350:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	1	3	theme	qualitative	289:299	arg1	analyses					318:325	qualitative and quantitative analyses	289:325	qualitative and quantitative analyses	289:325	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	8	4	theme	slope	1412:1416	arg1	value					1418:1422	the slope value	1408:1422	the slope value	1408:1422	Furthermore, the slope value composed of the current, per the concentration of D-glucose as a detection response, was significantly maintained even after 14 days.					
35884266	4	5	theme	bioelectrochemical	775:792	arg1	nano-biosensor					794:807	a bioelectrochemical nano-biosensor	773:807	a bioelectrochemical nano-biosensor with high sensitivity and stability	773:843	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	2	6	with	environment	458:468	arg1	performance					479:489	the performance	475:489	the performance of the electron transport materials	475:525	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	7	7	from	range	1341:1345	arg1	mM					1391:1392	1.0 to 15.0 mM	1379:1392	1.0 to 15.0 mM	1379:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	1	8	theme	Electrochemical	89:103	arg1	systems					120:126	Electrochemical nano-biosensor systems	89:126	Electrochemical nano-biosensor systems	89:126	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	4	9	theme	transfer	734:741	arg1	capability					743:752	strong stability and electron transfer capability	704:752	strong stability and electron transfer capability	704:752	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	1	10	theme	medical	191:197	arg1	evaluations					176:186	evaluations	176:186	evaluations of medical, agricultural, environmental and sports analysis	176:246	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	5	11	theme	mediator-modified	851:867	arg1	composite					899:907	the GO/Co/chitosan composite	880:907	the GO/Co/chitosan composite	880:907	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	5	11	theme	mediator-modified	851:867	arg1	electrode					869:877	a mediator-modified electrode	849:877	a mediator-modified electrode	849:877	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	1	12	from	field	158:162	arg1	popular					132:138	popular	132:138	popular	132:138	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	1	13	theme	nano-biosensor	105:118	arg1	systems					120:126	Electrochemical nano-biosensor systems	89:126	Electrochemical nano-biosensor systems	89:126	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	4	14	theme	stability	711:719	arg1	capability					743:752	strong stability and electron transfer capability	704:752	strong stability and electron transfer capability	704:752	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	2	15	theme	transport	507:515	arg1	materials					517:525	the electron transport materials	494:525	the electron transport materials	494:525	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	4	16	theme	high	814:817	arg1	sensitivity					819:829	high sensitivity	814:829	high sensitivity	814:829	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	6	17	theme	composite	1152:1160	arg1	ability					1122:1128	the electron transfer ability	1100:1128	the electron transfer ability of the GO/Co/chitosan composite	1100:1160	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	6	17	theme	composite	1152:1160	arg1	excellent					1166:1174	excellent	1166:1174	excellent	1166:1174	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	1	18	theme	agricultural	200:211	arg1	evaluations					176:186	evaluations	176:186	evaluations of medical, agricultural, environmental and sports analysis	176:246	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	2	19	theme	electron	498:505	arg1	materials					517:525	the electron transport materials	494:525	the electron transport materials	494:525	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	1	20	theme	quantitative	305:316	arg1	analyses					318:325	qualitative and quantitative analyses	289:325	qualitative and quantitative analyses	289:325	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	5	21	theme	film	947:950	arg1	electrode					952:960	an Au film electrode	941:960	an Au film electrode	941:960	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	4	22	theme	electron	725:732	arg1	transfer					734:741	electron transfer	725:741	electron transfer	725:741	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	0	23	theme	Nano-Biosensor	36:49	arg1	Development					0:10	Development	0:10	Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.	0:87	Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.					
35884266	7	24	dep	15.0	1386:1389	arg1	to					1383:1384	to	1383:1384	to	1383:1384	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	7	25	theme	high	1336:1339	arg1	range					1341:1345	a high range	1334:1345	a high range of detected concentrations from 1.0 to 15.0 mM	1334:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	0	26	theme	GO/Co/Chitosan-Based	15:34	arg1	Nano-Biosensor					36:49	GO/Co/Chitosan-Based Nano-Biosensor	15:49	GO/Co/Chitosan-Based Nano-Biosensor	15:49	Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.					
35884266	4	27	contain	had	700:702	arg1	composite					647:655	a composite	645:655	a composite composed of graphite oxide/cobalt/chitosan	645:698	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	4	27	contain	had	700:702	arg2	capability					743:752	strong stability and electron transfer capability	704:752	strong stability and electron transfer capability	704:752	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	5	28	theme	glucose	988:994	arg1	oxidase					996:1002	glucose oxidase	988:1002	glucose oxidase as a receptor	988:1016	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	4	29	theme	graphite	669:676	arg1	oxide/cobalt/chitosan					678:698	graphite oxide/cobalt/chitosan	669:698	graphite oxide/cobalt/chitosan	669:698	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	0	30	theme	Real-Time	55:63	arg1	Detection					65:73	Real-Time Detection	55:73	Real-Time Detection of D-Glucose	55:86	Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.					
35884266	1	31	theme	high	332:335	arg1	sensitivity					337:347	high sensitivity	332:347	high sensitivity	332:347	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	4	32	theme	strong	704:709	arg1	capability					743:752	strong stability and electron transfer capability	704:752	strong stability and electron transfer capability	704:752	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	1	33	dep	agricultural	200:211	arg1	environmental					214:226	environmental	214:226	environmental	214:226	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	5	34	theme	covalent	965:972	arg1	boding					974:979	covalent boding	965:979	covalent boding	965:979	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	1	35	theme	sports	232:237	arg1	analysis					239:246	sports analysis	232:246	sports analysis	232:246	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	2	36	theme	surrounding	446:456	arg1	environment					458:468	the surrounding environment	442:468	the surrounding environment with the performance of the electron transport materials	442:525	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	7	37	theme	real-time	1232:1240	arg1	detection					1242:1250	the real-time detection	1228:1250	the real-time detection of D-glucose	1228:1263	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	1	38	theme	analysis	239:246	arg1	evaluations					176:186	evaluations	176:186	evaluations of medical, agricultural, environmental and sports analysis	176:246	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	6	39	theme	transfer	1113:1120	arg1	ability					1122:1128	the electron transfer ability	1100:1128	the electron transfer ability of the GO/Co/chitosan composite	1100:1160	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	6	39	theme	transfer	1113:1120	arg1	excellent					1166:1174	excellent	1166:1174	excellent	1166:1174	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	8	40	theme	D-glucose	1474:1482	arg1	concentration					1457:1469	the concentration	1453:1469	the concentration of D-glucose as a detection response	1453:1506	Furthermore, the slope value composed of the current, per the concentration of D-glucose as a detection response, was significantly maintained even after 14 days.					
35884266	7	41	theme	concentrations	1359:1372	arg1	range					1341:1345	a high range	1334:1345	a high range of detected concentrations from 1.0 to 15.0 mM	1334:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	2	42	theme	materials	517:525	arg1	performance					479:489	the performance	475:489	the performance of the electron transport materials	475:525	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	1	43	theme	industrial	147:156	arg1	field					158:162	the industrial field	143:162	the industrial field	143:162	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	1	44	from	popular	132:138	arg1	field					158:162	the industrial field	143:162	the industrial field	143:162	Electrochemical nano-biosensor systems are popular in the industrial field, along with evaluations of medical, agricultural, environmental and sports analysis, because they can simultaneously perform qualitative and quantitative analyses with high sensitivity.					
35884266	5	45	theme	composite	1067:1075	arg1	end					1041:1043	the end	1037:1043	the end of the GO/Co/chitosan composite	1037:1075	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	7	46	from	mM	1391:1392	arg1	range					1341:1345	a high range	1334:1345	a high range of detected concentrations from 1.0 to 15.0 mM	1334:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	7	46	from	mM	1391:1392	arg1	concentrations					1359:1372	detected concentrations	1350:1372	detected concentrations from 1.0 to 15.0 mM	1350:1392	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	3	47	theme	many	539:542	arg1	researchers					544:554	many researchers	539:554	many researchers	539:554	Therefore, many researchers are trying to find good factors for real-time detection.					
35884266	6	48	theme	power	1191:1195	arg1	analysis					1205:1212	power density analysis	1191:1212	power density analysis	1191:1212	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	6	49	theme	electron	1104:1111	arg1	ability					1122:1128	the electron transfer ability	1100:1128	the electron transfer ability of the GO/Co/chitosan composite	1100:1160	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	6	49	theme	electron	1104:1111	arg1	excellent					1166:1174	excellent	1166:1174	excellent	1166:1174	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	3	50	theme	real-time	592:600	arg1	detection					602:610	real-time detection	592:610	real-time detection	592:610	Therefore, many researchers are trying to find good factors for real-time detection.					
35884266	6	51	theme	GO/Co/chitosan	1137:1150	arg1	composite					1152:1160	the GO/Co/chitosan composite	1133:1160	the GO/Co/chitosan composite	1133:1160	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	2	52	theme	real-time	359:367	arg1	detection					369:377	real-time detection	359:377	real-time detection using an electrochemical nano-biosensor	359:417	However, real-time detection using an electrochemical nano-biosensor is greatly affected by the surrounding environment with the performance of the electron transport materials.					
35884266	6	53	theme	density	1197:1203	arg1	analysis					1205:1212	power density analysis	1191:1212	power density analysis	1191:1212	It was confirmed that the electron transfer ability of the GO/Co/chitosan composite was excellent, as shown with power density analysis.					
35884266	7	54	theme	developed	1304:1312	arg1	nano-biosensor					1314:1327	the developed nano-biosensor	1300:1327	the developed nano-biosensor	1300:1327	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35884266	5	55	theme	Au	944:945	arg1	electrode					952:960	an Au film electrode	941:960	an Au film electrode	941:960	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	4	56	located	found	634:638	arg2	it					627:628	it	627:628	it	627:628	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	4	56	located	found	634:638	arg1	work					621:624	this work	616:624	this work	616:624	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	3	57	theme	good	575:578	arg1	factors					580:586	good factors	575:586	good factors for real-time detection	575:610	Therefore, many researchers are trying to find good factors for real-time detection.					
35884266	0	58	theme	D-Glucose	78:86	arg1	Detection					65:73	Real-Time Detection	55:73	Real-Time Detection of D-Glucose	55:86	Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.					
35884266	4	59	with	nano-biosensor	794:807	arg1	sensitivity					819:829	high sensitivity	814:829	high sensitivity	814:829	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	4	59	with	nano-biosensor	794:807	arg1	stability					835:843	stability	835:843	stability	835:843	In this work, it was found that a composite composed of graphite oxide/cobalt/chitosan had strong stability and electron transfer capability and was applied to a bioelectrochemical nano-biosensor with high sensitivity and stability.					
35884266	8	60	theme	detection	1489:1497	arg1	response					1499:1506	a detection response	1487:1506	a detection response	1487:1506	Furthermore, the slope value composed of the current, per the concentration of D-glucose as a detection response, was significantly maintained even after 14 days.					
35884266	5	61	theme	GO/Co/chitosan	884:897	arg1	composite					899:907	the GO/Co/chitosan composite	880:907	the GO/Co/chitosan composite	880:907	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	5	61	theme	GO/Co/chitosan	884:897	arg1	electrode					869:877	a mediator-modified electrode	849:877	a mediator-modified electrode	849:877	As a mediator-modified electrode, the GO/Co/chitosan composite was electrically deposited onto an Au film electrode by covalent boding, while glucose oxidase as a receptor was immobilized on the end of the GO/Co/chitosan composite.					
35884266	7	62	theme	D-glucose	1255:1263	arg1	detection					1242:1250	the real-time detection	1228:1250	the real-time detection of D-glucose	1228:1263	In addition, the real-time detection of D-glucose could be successfully performed by the developed nano-biosensor with a high range of detected concentrations from 1.0 to 15.0 mM.					
35737877	4	0	theme	molecular	907:915	arg1	weight					917:922	a higher molecular weight	898:922	a higher molecular weight	898:922	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	2	1	theme	bioactivity	325:335	arg1	lack					317:320	the lack	313:320	the lack of bioactivity of PNIPAM	313:345	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	4	2	theme	°C.	871:873	arg1	PNIPAM-Chi					875:884	31 to 33 °C. PNIPAM-Chi	862:884	31 to 33 °C. PNIPAM-Chi	862:884	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	9	3	theme	hydrophobic	2040:2050	arg1	surfaces					2052:2059	The slightly more hydrophobic surfaces	2022:2059	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C	2022:2096	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	8	4	theme	heparin	2013:2019	arg1	bioactivity					1998:2008	the bioactivity	1994:2008	the bioactivity of heparin	1994:2019	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	3	5	theme	layer-by-layer	599:612	arg1	assembly					614:621	a layer-by-layer assembly	597:621	a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs)	597:715	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	8	6	theme	more	1839:1842	arg1	spreading					1844:1852	more spreading	1839:1852	more spreading	1839:1852	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	6	7	theme	systems	1612:1618	arg1	stability					1595:1603	the stability	1591:1603	the stability of the systems	1591:1618	Subsequently, the multilayers are covalently cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide to strengthen the stability of the systems under physiological conditions.					
35737877	9	8	theme	PNIPAM-PEMs	2077:2087	arg1	surfaces					2052:2059	The slightly more hydrophobic surfaces	2022:2059	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C	2022:2096	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	2	9	theme	PNIPAM	340:345	arg1	bioactivity					325:335	bioactivity	325:335	bioactivity of PNIPAM	325:345	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	8	10	theme	multipotent	1867:1877	arg1	fibroblasts					1895:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	3	11	with	PNIPAM	527:532	arg1	chitosan					539:546	chitosan	539:546	chitosan	539:546	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	8	12	theme	mouse	1889:1893	arg1	fibroblasts					1895:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	1	13	theme	drug	267:270	arg1	release					272:278	controlled drug release	256:278	controlled drug release	256:278	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	10	14	theme	factors	2339:2345	arg1	release					2321:2327	thermally uploading and controlled release	2286:2327	thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2286:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	3	15	theme	polyelectrolyte	675:689	arg1	multilayers					691:701	PNIPAM-modified polyelectrolyte multilayers	659:701	PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs)	659:715	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	3	15	theme	polyelectrolyte	675:689	arg1	PNIPAM-PEMs					704:714	PNIPAM-PEMs	704:714	PNIPAM-PEMs	704:714	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	4	16	theme	higher	929:934	arg1	degree					936:941	a higher degree	927:941	a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	927:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	10	17	theme	constructed	2161:2171	arg1	PNIPAM-PEM					2173:2182	layer-by-layer constructed PNIPAM-PEM	2146:2182	layer-by-layer constructed PNIPAM-PEM with cross-linking	2146:2201	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	1	18	theme	tissue	284:289	arg1	engineering					291:301	tissue engineering	284:301	tissue engineering	284:301	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	10	19	theme	tissue	2369:2374	arg1	regeneration					2376:2387	tissue regeneration	2369:2387	tissue regeneration	2369:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	0	20	theme	Stable	15:20	arg1	Multilayers					35:45	Stable Cross-Linked Multilayers	15:45	Stable Cross-Linked Multilayers	15:45	Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and Biocompatibility.					
35737877	4	21	from	temperature	832:842	arg1	PNIPAM-Chi					875:884	31 to 33 °C. PNIPAM-Chi	862:884	31 to 33 °C. PNIPAM-Chi	862:884	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	21	from	temperature	832:842	arg1	range					851:855	the range	847:855	the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	847:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	5	22	theme	Little	1136:1141	arg1	difference					1143:1152	Little difference	1136:1152	Little difference of layer growth	1136:1168	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	8	23	theme	heparin	1947:1953	arg1	layers					1964:1969	heparin terminal layers	1947:1969	heparin terminal layers	1947:1969	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	2	24	from	use	361:363	arg1	systems					384:390	cell-containing systems	368:390	cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation	368:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	4	25	theme	chains	969:974	arg1	substitution					946:957	substitution	946:957	substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	946:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	26	theme	point	821:825	arg1	temperature					832:842	the cloud point (CP) temperature	811:842	the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	811:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	0	27	theme	Physiochemical	122:135	arg1	Properties					137:146	Their Physiochemical Properties	116:146	Their Physiochemical Properties	116:146	Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and Biocompatibility.					
35737877	10	28	theme	thermally	2286:2294	arg1	release					2321:2327	thermally uploading and controlled release	2286:2327	thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2286:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	4	29	theme	CP	828:829	arg1	temperature					832:842	the cloud point (CP) temperature	811:842	the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	811:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	7	30	from	pH	1747:1748	arg1	buffer					1737:1742	the physiological buffer	1719:1742	the physiological buffer at pH 7.4	1719:1752	Ellipsometry results confirm the layer integrity after exposure to the physiological buffer at pH 7.4 compared to those without cross-linking.					
35737877	4	31	theme	dynamic	1045:1051	arg1	scattering					1059:1068	dynamic light scattering	1045:1068	dynamic light scattering	1045:1068	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	32	dep	33	868:869	arg1	to					865:866	to	865:866	to	865:866	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	9	33	dep	cell	2112:2115	arg1	attachment					2117:2126	attachment	2117:2126	attachment	2117:2126	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	2	34	dep	cell	467:470	arg1	differentiation					483:497	differentiation	483:497	differentiation	483:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	2	34	dep	cell	467:470	arg1	growth					472:477	growth	472:477	growth	472:477	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	5	35	theme	striking	1328:1335	arg1	abilities					1360:1368	striking swelling-and-shrinking abilities	1328:1368	striking swelling-and-shrinking abilities	1328:1368	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	0	36	theme	Multilayers	35:45	arg1	Engineering					0:10	Engineering	0:10	Engineering of Stable Cross-Linked Multilayers	0:45	Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and Biocompatibility.					
35737877	8	37	from	adhesion	1826:1833	arg1	PEMs					1923:1926	cross-linked PEMs	1910:1926	cross-linked PEMs	1910:1926	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	5	38	theme	dissipation	1421:1431	arg1	monitoring					1433:1442	dissipation monitoring	1421:1442	dissipation monitoring	1421:1442	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	5	39	theme	growth	1163:1168	arg1	difference					1143:1152	Little difference	1136:1152	Little difference of layer growth	1136:1168	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	2	40	from	effect	457:462	arg1	cell					467:470	cell growth and differentiation	467:497	cell growth and differentiation	467:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	10	41	theme	culture	2234:2240	arg1	system					2242:2247	an interesting cell culture system	2214:2247	an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2214:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	2	42	theme	cell-containing	368:382	arg1	systems					384:390	cell-containing systems	368:390	cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation	368:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	2	43	with	substratum	427:436	arg1	effect					457:462	no regulating effect	443:462	no regulating effect on cell growth and differentiation	443:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	10	44	theme	interesting	2217:2227	arg1	system					2242:2247	an interesting cell culture system	2214:2247	an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2214:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	6	45	theme	physiological	1626:1638	arg1	conditions					1640:1649	physiological conditions	1626:1649	physiological conditions	1626:1649	Subsequently, the multilayers are covalently cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide to strengthen the stability of the systems under physiological conditions.					
35737877	5	46	theme	quartz	1388:1393	arg1	microbalance					1403:1414	quartz crystal microbalance	1388:1414	quartz crystal microbalance with dissipation monitoring	1388:1442	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	5	47	theme	plasmon	1243:1249	arg1	resonance					1251:1259	surface plasmon resonance	1235:1259	surface plasmon resonance	1235:1259	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	3	48	with	assembly	614:621	arg1	heparin					638:644	bioactive heparin	628:644	bioactive heparin	628:644	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	10	49	dep	thermally	2286:2294	arg1	uploading					2296:2304	uploading	2296:2304	uploading	2296:2304	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	2	50	theme	thermo-responsive	400:416	arg1	substratum					427:436	a thermo-responsive adhesive substratum	398:436	a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation	398:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	9	51	link	cross-linked	2064:2075	arg1	PNIPAM-PEMs					2077:2087	cross-linked PNIPAM-PEMs	2064:2087	cross-linked PNIPAM-PEMs	2064:2087	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	6	52	theme	1-ethyl-3-	1509:1518	arg1	carbodiimide/N-hydroxysuccinimide					1543:1575	1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide	1509:1575	1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide	1509:1575	Subsequently, the multilayers are covalently cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide to strengthen the stability of the systems under physiological conditions.					
35737877	4	53	theme	higher	900:905	arg1	weight					917:922	a higher molecular weight	898:922	a higher molecular weight	898:922	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	9	54	theme	more	2035:2038	arg1	surfaces					2052:2059	The slightly more hydrophobic surfaces	2022:2059	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C	2022:2096	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	8	55	theme	higher	1819:1824	arg1	adhesion					1826:1833	significantly higher adhesion	1805:1833	significantly higher adhesion	1805:1833	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	8	56	link	cross-linked	1910:1921	arg1	PEMs					1923:1926	cross-linked PEMs	1910:1926	cross-linked PEMs	1910:1926	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	4	57	theme	2	751:751	arg1	chains					734:739	PNIPAM chains	727:739	PNIPAM chains of either 2 (LMW) or 10 kDa (HMW)	727:773	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	10	58	with	PNIPAM-PEM	2173:2182	arg1	cross-linking					2189:2201	cross-linking	2189:2201	cross-linking	2189:2201	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	9	59	theme	cross-linked	2064:2075	arg1	PNIPAM-PEMs					2077:2087	cross-linked PNIPAM-PEMs	2064:2087	cross-linked PNIPAM-PEMs	2064:2087	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	3	60	theme	bioactive	628:636	arg1	heparin					638:644	bioactive heparin	628:644	bioactive heparin	628:644	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	4	61	from	pH	1130:1131	arg1	polyanion					1117:1125	a polyanion	1115:1125	a polyanion at pH 4	1115:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	61	from	pH	1130:1131	arg1	PEM					1095:1097	PEM	1095:1097	PEM	1095:1097	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	62	theme	PNIPAM	727:732	arg1	chains					734:739	PNIPAM chains	727:739	PNIPAM chains of either 2 (LMW) or 10 kDa (HMW)	727:773	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	8	63	theme	C3H10T1/2	1857:1865	arg1	fibroblasts					1895:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	1	64	theme	controlled	256:265	arg1	release					272:278	controlled drug release	256:278	controlled drug release	256:278	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	7	65	theme	physiological	1723:1735	arg1	buffer					1737:1742	the physiological buffer	1719:1742	the physiological buffer at pH 7.4	1719:1752	Ellipsometry results confirm the layer integrity after exposure to the physiological buffer at pH 7.4 compared to those without cross-linking.					
35737877	4	66	theme	substitution	946:957	arg1	weight					917:922	a higher molecular weight	898:922	a higher molecular weight	898:922	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	66	theme	substitution	946:957	arg1	degree					936:941	a higher degree	927:941	a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	927:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	8	67	with	PEMs	1923:1926	arg1	layers					1964:1969	heparin terminal layers	1947:1969	heparin terminal layers	1947:1969	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	3	68	theme	PNIPAM-modified	659:673	arg1	multilayers					691:701	PNIPAM-modified polyelectrolyte multilayers	659:701	PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs)	659:715	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	3	68	theme	PNIPAM-modified	659:673	arg1	PNIPAM-PEMs					704:714	PNIPAM-PEMs	704:714	PNIPAM-PEMs	704:714	In this study, integrating PNIPAM with chitosan into PNIPAM-grafted-chitosan (PNIPAM-Chi) allows a layer-by-layer assembly with bioactive heparin to fabricate PNIPAM-modified polyelectrolyte multilayers (PNIPAM-PEMs).					
35737877	8	69	theme	embryonic	1879:1887	arg1	fibroblasts					1895:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	C3H10T1/2 multipotent embryonic mouse fibroblasts	1857:1905	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	10	70	theme	growth	2332:2337	arg1	factors					2339:2345	growth factors	2332:2345	growth factors that further promotes tissue regeneration	2332:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	4	71	dep	increase	1001:1008	arg1	ensured					1034:1040	ensured	1034:1040	ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	1034:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	8	72	theme	fibroblasts	1895:1905	arg1	adhesion					1826:1833	significantly higher adhesion	1805:1833	significantly higher adhesion	1805:1833	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	8	72	theme	fibroblasts	1895:1905	arg1	spreading					1844:1852	more spreading	1839:1852	more spreading	1839:1852	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	1	73	theme	thermo-responsive	174:190	arg1	N-isopropylacrylamide					197:217	N-isopropylacrylamide	197:217	N-isopropylacrylamide	197:217	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	1	73	theme	thermo-responsive	174:190	arg1	PNIPAM					221:226	PNIPAM	221:226	PNIPAM	221:226	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	1	73	theme	thermo-responsive	174:190	arg1	poly					192:195	The thermo-responsive poly	170:195	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM)	170:227	The thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) is ubiquitously applied in controlled drug release and tissue engineering.					
35737877	10	74	theme	controlled	2310:2319	arg1	release					2321:2327	thermally uploading and controlled release	2286:2327	thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2286:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	8	75	theme	cross-linked	1910:1921	arg1	PEMs					1923:1926	cross-linked PEMs	1910:1926	cross-linked PEMs	1910:1926	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	7	76	theme	layer	1685:1689	arg1	integrity					1691:1699	the layer integrity	1681:1699	the layer integrity	1681:1699	Ellipsometry results confirm the layer integrity after exposure to the physiological buffer at pH 7.4 compared to those without cross-linking.					
35737877	4	77	theme	significant	989:999	arg1	increase					1001:1008	a significant increase	987:1008	a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	987:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	78	with	range	851:855	arg1	weight					917:922	a higher molecular weight	898:922	a higher molecular weight	898:922	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	78	with	range	851:855	arg1	degree					936:941	a higher degree	927:941	a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	927:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	79	theme	kDa	765:767	arg1	chains					734:739	PNIPAM chains	727:739	PNIPAM chains of either 2 (LMW) or 10 kDa (HMW)	727:773	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	7	80	theme	Ellipsometry	1652:1663	arg1	results					1665:1671	Ellipsometry results	1652:1671	Ellipsometry results	1652:1671	Ellipsometry results confirm the layer integrity after exposure to the physiological buffer at pH 7.4 compared to those without cross-linking.					
35737877	4	81	theme	PNIPAM	962:967	arg1	chains					969:974	PNIPAM chains	962:974	PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	962:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	82	theme	cloud	815:819	arg1	temperature					832:842	the cloud point (CP) temperature	811:842	the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	811:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	5	83	theme	swelling-and-shrinking	1337:1358	arg1	abilities					1360:1368	striking swelling-and-shrinking abilities	1328:1368	striking swelling-and-shrinking abilities	1328:1368	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	4	84	from	PNIPAM-Chi	875:884	arg1	temperature					832:842	the cloud point (CP) temperature	811:842	the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	811:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	4	84	from	PNIPAM-Chi	875:884	arg1	range					851:855	the range	847:855	the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4	847:1133	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	8	85	theme	terminal	1955:1962	arg1	layers					1964:1969	heparin terminal layers	1947:1969	heparin terminal layers	1947:1969	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	5	86	with	microbalance	1403:1414	arg1	monitoring					1433:1442	dissipation monitoring	1421:1442	dissipation monitoring	1421:1442	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	2	87	theme	regulating	446:455	arg1	effect					457:462	no regulating effect	443:462	no regulating effect on cell growth and differentiation	443:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
35737877	4	88	theme	chitosan	782:789	arg1	backbone					791:798	the chitosan backbone	778:798	the chitosan backbone	778:798	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	0	89	theme	Cross-Linked	22:33	arg1	Multilayers					35:45	Stable Cross-Linked Multilayers	15:45	Stable Cross-Linked Multilayers	15:45	Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and Biocompatibility.					
35737877	4	90	theme	light	1053:1057	arg1	scattering					1059:1068	dynamic light scattering	1045:1068	dynamic light scattering	1045:1068	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	5	91	theme	chosen	1194:1199	arg1	PNIPAM-Chi					1201:1210	the chosen PNIPAM-Chi	1190:1210	the chosen PNIPAM-Chi used as polycations	1190:1230	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	9	92	from	°C	2095:2096	arg1	surfaces					2052:2059	The slightly more hydrophobic surfaces	2022:2059	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C	2022:2096	The slightly more hydrophobic surfaces of cross-linked PNIPAM-PEMs at 37 °C also increase cell attachment and growth.					
35737877	4	93	from	increase	1001:1008	arg1	diameter					1013:1020	diameter	1013:1020	diameter	1013:1020	Grafting PNIPAM chains of either 2 (LMW) or 10 kDa (HMW) on the chitosan backbone influences the cloud point (CP) temperature in the range from 31 to 33 °C. PNIPAM-Chi with either a higher molecular weight or a higher degree of substitution of PNIPAM chains exhibiting a significant increase in diameter above CP as ensured by dynamic light scattering is selected to fabricate PEM with heparin as a polyanion at pH 4.					
35737877	0	94	theme	Thermo-Responsive	56:72	arg1	PNIPAM-Grafted-Chitosan/Heparin					74:104	Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin	56:104	Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin	56:104	Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and Biocompatibility.					
35737877	5	95	theme	layer	1157:1161	arg1	growth					1163:1168	layer growth	1157:1168	layer growth	1157:1168	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	6	96	dep	1-ethyl-3-	1509:1518	arg1	3-dimethylaminopropyl					1520:1540	3-dimethylaminopropyl	1520:1540	3-dimethylaminopropyl	1520:1540	Subsequently, the multilayers are covalently cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide to strengthen the stability of the systems under physiological conditions.					
35737877	10	97	theme	cell	2229:2232	arg1	system					2242:2247	an interesting cell culture system	2214:2247	an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration	2214:2387	Thus, layer-by-layer constructed PNIPAM-PEM with cross-linking represents an interesting cell culture system that can be potentially employed for thermally uploading and controlled release of growth factors that further promotes tissue regeneration.					
35737877	5	98	theme	surface	1235:1241	arg1	resonance					1251:1259	surface plasmon resonance	1235:1259	surface plasmon resonance	1235:1259	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	8	99	from	spreading	1844:1852	arg1	PEMs					1923:1926	cross-linked PEMs	1910:1926	cross-linked PEMs	1910:1926	Moreover, significantly higher adhesion and more spreading of C3H10T1/2 multipotent embryonic mouse fibroblasts on cross-linked PEMs, particularly with heparin terminal layers, are observed owing to the bioactivity of heparin.					
35737877	5	100	theme	crystal	1395:1401	arg1	microbalance					1403:1414	quartz crystal microbalance	1388:1414	quartz crystal microbalance with dissipation monitoring	1388:1442	Little difference of layer growth is detected between the chosen PNIPAM-Chi used as polycations by surface plasmon resonance, while multilayers formed with HMW-0.02 are more hydrated and show striking swelling-and-shrinking abilities when studied with quartz crystal microbalance with dissipation monitoring.					
35737877	2	101	theme	adhesive	418:425	arg1	substratum					427:436	a thermo-responsive adhesive substratum	398:436	a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation	398:497	However, the lack of bioactivity of PNIPAM restricts its use in cell-containing systems being a thermo-responsive adhesive substratum with no regulating effect on cell growth and differentiation.					
36690233	9	0	theme	groups	1308:1313	arg1	half					1290:1293	the other half	1280:1293	the other half of the amino groups of chitosan	1280:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	7	1	theme	chitosan	1179:1186	arg1	chitosan					1179:1186	chitosan	1179:1186	chitosan	1179:1186	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	1	theme	chitosan	1179:1186	arg1	groups					1169:1174	the amino groups	1159:1174	the amino groups of chitosan	1159:1186	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	2	theme	amino	1163:1167	arg1	chitosan					1179:1186	chitosan	1179:1186	chitosan	1179:1186	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	2	theme	amino	1163:1167	arg1	groups					1169:1174	the amino groups	1159:1174	the amino groups of chitosan	1159:1186	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	9	3	theme	Amidation	1217:1225	arg1	form					1263:1266	the primary interaction form	1239:1266	the primary interaction form	1239:1266	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	9	3	theme	Amidation	1217:1225	arg1	reaction					1227:1234	Amidation reaction	1217:1234	Amidation reaction	1217:1234	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	7	4	theme	N	1087:1087	arg1	donates					1112:1118	electron donates	1103:1118	electron donates from N to Fe	1103:1131	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	4	theme	N	1087:1087	arg1	interaction					1072:1082	The primary interaction	1060:1082	The primary interaction	1060:1082	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	4	theme	N	1087:1087	arg1	-Fe					1093:1095	N(NH2)-Fe(III)	1087:1100	N(NH2)-Fe(III)	1087:1100	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	3	5	theme	infrared	502:509	arg1	FTIR					525:528	FTIR	525:528	FTIR	525:528	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	5	theme	infrared	502:509	arg1	spectroscopy					511:522	infrared spectroscopy	502:522	infrared spectroscopy (FTIR)	502:529	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	5	6	from	interaction	988:998	arg1	MCG					1029:1031	MCG	1029:1031	MCG	1029:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	5	7	theme	couplet	1007:1013	arg1	components					1015:1024	the couplet components	1003:1024	the couplet components in MCG	1003:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	2	8	theme	solvothermal	351:362	arg1	method					364:369	solvothermal method	351:369	solvothermal method	351:369	Herein, ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO) was facilely prepared via solvothermal method.					
36690233	2	9	theme	graphene	305:312	arg1	oxide					314:318	graphene oxide	305:318	graphene oxide (GO)	305:323	Herein, ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO) was facilely prepared via solvothermal method.					
36690233	5	10	theme	site	983:986	arg1	interaction					988:998	the probable site to site interaction	962:998	the probable site to site interaction of the couplet components in MCG	962:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	1	11	theme	promising	189:197	arg1	application					199:209	promising application	189:209	promising application in environmental remediation	189:238	Magnetic nanohybrid combining chitosan and graphene have demonstrated promising application in environmental remediation.					
36690233	0	12	theme	solvothermal	98:109	arg1	method					111:116	solvothermal method	98:116	solvothermal method	98:116	Combination mechanism of the ternary composite based on Fe3O4-chitosan-graphene oxide prepared by solvothermal method.					
36690233	7	13	from	N	1125:1125	arg1	donates					1112:1118	electron donates	1103:1118	electron donates from N to Fe	1103:1131	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	13	from	N	1125:1125	arg1	-Fe					1093:1095	N(NH2)-Fe(III)	1087:1100	N(NH2)-Fe(III)	1087:1100	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	5	14	from	MCG	1029:1031	arg1	interaction					988:998	the probable site to site interaction	962:998	the probable site to site interaction of the couplet components in MCG	962:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	13	15	from	architecture	1646:1657	arg1	design					1583:1588	the design	1579:1588	the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture	1579:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	7	16	theme	NH2	1089:1091	arg1	donates					1112:1118	electron donates	1103:1118	electron donates from N to Fe	1103:1131	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	16	theme	NH2	1089:1091	arg1	interaction					1072:1082	The primary interaction	1060:1082	The primary interaction	1060:1082	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	16	theme	NH2	1089:1091	arg1	-Fe					1093:1095	N(NH2)-Fe(III)	1087:1100	N(NH2)-Fe(III)	1087:1100	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	11	17	theme	aromatic	1411:1418	arg1	ring					1420:1423	aromatic ring	1411:1423	aromatic ring	1411:1423	Dominant interactions are those of epoxy, hydroxyl and aromatic ring with Fe(III).					
36690233	4	18	theme	photoelectron	804:816	arg1	XPS					832:834	XPS	832:834	XPS	832:834	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	18	theme	photoelectron	804:816	arg1	spectroscopy					818:829	X-ray photoelectron spectroscopy	798:829	X-ray photoelectron spectroscopy (XPS)	798:835	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	13	19	theme	adsorbent	1603:1611	arg1	based					1613:1617	efficient adsorbent based	1593:1617	efficient adsorbent based on Fe3O4-chitosan-graphene architecture	1593:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	5	20	theme	MCG	940:942	arg1	mechanism					927:935	combination mechanism	915:935	combination mechanism of MCG	915:942	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	0	21	theme	composite	37:45	arg1	mechanism					12:20	Combination mechanism	0:20	Combination mechanism of the ternary composite	0:45	Combination mechanism of the ternary composite based on Fe3O4-chitosan-graphene oxide prepared by solvothermal method.					
36690233	13	22	from	based	1613:1617	arg1	architecture					1646:1657	Fe3O4-chitosan-graphene architecture	1622:1657	Fe3O4-chitosan-graphene architecture	1622:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	3	23	dep	Fourier	484:490	arg1	transform					492:500	transform	492:500	transform infrared spectroscopy (FTIR)	492:529	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	5	24	from	components	1015:1024	arg1	MCG					1029:1031	MCG	1029:1031	MCG	1029:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	13	25	theme	based	1613:1617	arg1	design					1583:1588	the design	1579:1588	the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture	1579:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	9	26	theme	interaction	1251:1261	arg1	form					1263:1266	the primary interaction form	1239:1266	the primary interaction form	1239:1266	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	9	26	theme	interaction	1251:1261	arg1	reaction					1227:1234	Amidation reaction	1217:1234	Amidation reaction	1217:1234	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	4	27	theme	emission	883:890	arg1	spectra					892:898	fluorescent emission spectra	871:898	fluorescent emission spectra	871:898	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	5	28	theme	probable	966:973	arg1	interaction					988:998	the probable site to site interaction	962:998	the probable site to site interaction of the couplet components in MCG	962:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	12	29	theme	consecutive	1522:1532	arg1	cycles					1534:1539	six consecutive cycles	1518:1539	six consecutive cycles	1518:1539	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	1	30	theme	environmental	214:226	arg1	remediation					228:238	environmental remediation	214:238	environmental remediation	214:238	Magnetic nanohybrid combining chitosan and graphene have demonstrated promising application in environmental remediation.					
36690233	0	31	theme	Combination	0:10	arg1	mechanism					12:20	Combination mechanism	0:20	Combination mechanism of the ternary composite	0:45	Combination mechanism of the ternary composite based on Fe3O4-chitosan-graphene oxide prepared by solvothermal method.					
36690233	12	32	theme	fair	1462:1465	arg1	performance					1478:1488	fair adsorption performance	1462:1488	fair adsorption performance	1462:1488	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	4	33	theme	fluorescent	871:881	arg1	spectra					892:898	fluorescent emission spectra	871:898	fluorescent emission spectra	871:898	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	5	34	theme	site	975:978	arg1	interaction					988:998	the probable site to site interaction	962:998	the probable site to site interaction of the couplet components in MCG	962:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	12	35	theme	divalent	1493:1500	arg1	metals					1508:1513	divalent heavy metals	1493:1513	divalent heavy metals in six consecutive cycles	1493:1539	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	4	36	theme	MCG	686:688	arg1	mechanism					673:681	The combination mechanism	657:681	The combination mechanism of MCG	657:688	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	13	37	theme	Fe3O4-chitosan-graphene	1622:1644	arg1	architecture					1646:1657	Fe3O4-chitosan-graphene architecture	1622:1657	Fe3O4-chitosan-graphene architecture	1622:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	12	38	theme	adsorption	1467:1476	arg1	performance					1478:1488	fair adsorption performance	1462:1488	fair adsorption performance	1462:1488	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	4	39	theme	spectroscopic	759:771	arg1	Ultraviolet-visible					838:856	Ultraviolet-visible	838:856	Ultraviolet-visible	838:856	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	39	theme	spectroscopic	759:771	arg1	spectroscopy					818:829	X-ray photoelectron spectroscopy	798:829	X-ray photoelectron spectroscopy (XPS)	798:835	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	39	theme	spectroscopic	759:771	arg1	spectra					892:898	fluorescent emission spectra	871:898	fluorescent emission spectra	871:898	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	39	theme	spectroscopic	759:771	arg1	investigations					773:786	spectroscopic investigations	759:786	spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra	759:898	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	3	40	theme	prepared	379:386	arg1	composite					388:396	The as prepared composite	372:396	The as prepared composite	372:396	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	1	41	theme	Magnetic	119:126	arg1	nanohybrid					128:137	Magnetic nanohybrid	119:137	Magnetic nanohybrid combining chitosan and graphene	119:169	Magnetic nanohybrid combining chitosan and graphene have demonstrated promising application in environmental remediation.					
36690233	7	42	theme	positive	1193:1200	arg1	N+					1202:1203	positive N+	1193:1203	positive N+	1193:1203	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	3	43	theme	X-ray	419:423	arg1	XRD					438:440	XRD	438:440	XRD	438:440	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	43	theme	X-ray	419:423	arg1	diffraction					425:435	X-ray diffraction	419:435	X-ray diffraction (XRD)	419:441	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	4	44	theme	hard-soft	721:729	arg1	theory					748:753	the hard-soft acid-base (HSAB) theory	717:753	the hard-soft acid-base (HSAB) theory	717:753	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	45	theme	combination	661:671	arg1	mechanism					673:681	The combination mechanism	657:681	The combination mechanism of MCG	657:688	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	3	46	theme	thermo	598:603	arg1	analysis					638:645	thermo gravimetric-differential thermal analysis	598:645	thermo gravimetric-differential thermal analysis (TG-DTA)	598:654	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	46	theme	thermo	598:603	arg1	TG-DTA					648:653	TG-DTA	648:653	TG-DTA	648:653	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	12	47	theme	heavy	1502:1506	arg1	metals					1508:1513	divalent heavy metals	1493:1513	divalent heavy metals in six consecutive cycles	1493:1539	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	3	48	theme	transmission	444:455	arg1	TEM					478:480	TEM	478:480	TEM	478:480	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	48	theme	transmission	444:455	arg1	microscopy					466:475	transmission electron microscopy	444:475	transmission electron microscopy (TEM)	444:481	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	0	49	theme	ternary	29:35	arg1	composite					37:45	the ternary composite	25:45	the ternary composite	25:45	Combination mechanism of the ternary composite based on Fe3O4-chitosan-graphene oxide prepared by solvothermal method.					
36690233	9	50	theme	other	1284:1288	arg1	half					1290:1293	the other half	1280:1293	the other half of the amino groups of chitosan	1280:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	7	51	theme	primary	1064:1070	arg1	interaction					1072:1082	The primary interaction	1060:1082	The primary interaction	1060:1082	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	51	theme	primary	1064:1070	arg1	-Fe					1093:1095	N(NH2)-Fe(III)	1087:1100	N(NH2)-Fe(III)	1087:1100	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	3	52	theme	gravimetric-differential	605:628	arg1	analysis					638:645	thermo gravimetric-differential thermal analysis	598:645	thermo gravimetric-differential thermal analysis (TG-DTA)	598:654	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	52	theme	gravimetric-differential	605:628	arg1	TG-DTA					648:653	TG-DTA	648:653	TG-DTA	648:653	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	53	theme	electron	457:464	arg1	TEM					478:480	TEM	478:480	TEM	478:480	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	53	theme	electron	457:464	arg1	microscopy					466:475	transmission electron microscopy	444:475	transmission electron microscopy (TEM)	444:481	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	13	54	theme	efficient	1593:1601	arg1	based					1613:1617	efficient adsorbent based	1593:1617	efficient adsorbent based on Fe3O4-chitosan-graphene architecture	1593:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	13	55	from	design	1583:1588	arg1	architecture					1646:1657	Fe3O4-chitosan-graphene architecture	1622:1657	Fe3O4-chitosan-graphene architecture	1622:1657	These explorations may shed light on the design of efficient adsorbent based on Fe3O4-chitosan-graphene architecture.					
36690233	9	56	theme	primary	1243:1249	arg1	form					1263:1266	the primary interaction form	1239:1266	the primary interaction form	1239:1266	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	9	56	theme	primary	1243:1249	arg1	reaction					1227:1234	Amidation reaction	1217:1234	Amidation reaction	1217:1234	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	4	57	theme	acid-base	731:739	arg1	theory					748:753	the hard-soft acid-base (HSAB) theory	717:753	the hard-soft acid-base (HSAB) theory	717:753	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	7	58	theme	electron	1103:1110	arg1	donates					1112:1118	electron donates	1103:1118	electron donates from N to Fe	1103:1131	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	7	58	theme	electron	1103:1110	arg1	-Fe					1093:1095	N(NH2)-Fe(III)	1087:1100	N(NH2)-Fe(III)	1087:1100	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	10	59	dep	GO-Fe3O4	1346:1353	arg1	3					1343:1343	3	1343:1343	3	1343:1343	(3) GO-Fe3O4.					
36690233	2	60	theme	ternary	249:255	arg1	MCG					267:269	ternary composite MCG	249:269	ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO)	249:323	Herein, ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO) was facilely prepared via solvothermal method.					
36690233	2	61	theme	composite	257:265	arg1	MCG					267:269	ternary composite MCG	249:269	ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO)	249:323	Herein, ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO) was facilely prepared via solvothermal method.					
36690233	2	62	dep	oxide	314:318	arg1	GO					321:322	GO	321:322	GO	321:322	Herein, ternary composite MCG based on Fe3O4, chitosan (CS) and graphene oxide (GO) was facilely prepared via solvothermal method.					
36690233	5	63	theme	components	1015:1024	arg1	interaction					988:998	the probable site to site interaction	962:998	the probable site to site interaction of the couplet components in MCG	962:1031	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	12	64	from	metals	1508:1513	arg1	cycles					1534:1539	six consecutive cycles	1518:1539	six consecutive cycles	1518:1539	Moreover, MCG exhibits fair adsorption performance on divalent heavy metals in six consecutive cycles.					
36690233	4	65	theme	HSAB	742:745	arg1	theory					748:753	the hard-soft acid-base (HSAB) theory	717:753	the hard-soft acid-base (HSAB) theory	717:753	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	9	66	theme	amino	1302:1306	arg1	chitosan					1318:1325	chitosan	1318:1325	chitosan	1318:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	9	66	theme	amino	1302:1306	arg1	groups					1308:1313	the amino groups	1298:1313	the amino groups of chitosan	1298:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	4	67	theme	X-ray	798:802	arg1	XPS					832:834	XPS	832:834	XPS	832:834	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	4	67	theme	X-ray	798:802	arg1	spectroscopy					818:829	X-ray photoelectron spectroscopy	798:829	X-ray photoelectron spectroscopy (XPS)	798:835	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	9	68	theme	-C	1332:1333	arg1	NH-					1337:1339	-C(O)NH-	1332:1339	-C(O)NH-	1332:1339	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	11	69	theme	Dominant	1356:1363	arg1	interactions					1365:1376	Dominant interactions	1356:1376	Dominant interactions	1356:1376	Dominant interactions are those of epoxy, hydroxyl and aromatic ring with Fe(III).					
36690233	5	70	dep	interaction	988:998	arg1	to					980:981	to	980:981	to	980:981	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	7	71	theme	groups	1169:1174	arg1	half					1151:1154	one half	1147:1154	one half of the amino groups of chitosan	1147:1186	The primary interaction is N(NH2)-Fe(III), electron donates from N to Fe, transforming one half of the amino groups of chitosan into positive N+.					
36690233	3	72	theme	thermal	630:636	arg1	analysis					638:645	thermo gravimetric-differential thermal analysis	598:645	thermo gravimetric-differential thermal analysis (TG-DTA)	598:654	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	3	72	theme	thermal	630:636	arg1	TG-DTA					648:653	TG-DTA	648:653	TG-DTA	648:653	The as prepared composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Raman, Brunauer/Emmett/Teller-Barret/Joyner/Halenda (BET-BJH) and thermo gravimetric-differential thermal analysis (TG-DTA).					
36690233	6	73	dep	CS-Fe3O4	1050:1057	arg1	1					1047:1047	1	1047:1047	1	1047:1047	(1) CS-Fe3O4.					
36690233	5	74	theme	combination	915:925	arg1	mechanism					927:935	combination mechanism	915:935	combination mechanism of MCG	915:942	Particularly, combination mechanism of MCG was elucidated by the probable site to site interaction of the couplet components in MCG, as follows.					
36690233	4	75	dep	Ultraviolet-visible	838:856	arg1	UV-Vis					859:864	UV-Vis	859:864	UV-Vis	859:864	The combination mechanism of MCG was unveiled via employing the hard-soft acid-base (HSAB) theory and spectroscopic investigations including X-ray photoelectron spectroscopy (XPS), Ultraviolet-visible (UV-Vis) and fluorescent emission spectra.					
36690233	0	76	theme	Fe3O4-chitosan-graphene	56:78	arg1	oxide					80:84	Fe3O4-chitosan-graphene oxide	56:84	Fe3O4-chitosan-graphene oxide prepared by solvothermal method	56:116	Combination mechanism of the ternary composite based on Fe3O4-chitosan-graphene oxide prepared by solvothermal method.					
36690233	8	77	dep	GO-CS	1210:1214	arg1	2					1207:1207	2	1207:1207	2	1207:1207	(2) GO-CS.					
36690233	1	78	from	application	199:209	arg1	remediation					228:238	environmental remediation	214:238	environmental remediation	214:238	Magnetic nanohybrid combining chitosan and graphene have demonstrated promising application in environmental remediation.					
36690233	9	79	theme	chitosan	1318:1325	arg1	chitosan					1318:1325	chitosan	1318:1325	chitosan	1318:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
36690233	9	79	theme	chitosan	1318:1325	arg1	groups					1308:1313	the amino groups	1298:1313	the amino groups of chitosan	1298:1325	Amidation reaction is the primary interaction form, converting the other half of the amino groups of chitosan into -C(O)NH-.					
35961522	9	0	theme	versatile	1713:1721	arg1	method					1764:1769	the versatile and environmentally friendly preparation method	1709:1769	the versatile and environmentally friendly preparation method	1709:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	1	1	theme	biofilm	285:291	arg1	formation					293:301	further biofilm formation	277:301	further biofilm formation	277:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	1	theme	biofilm	285:291	arg1	bacteria					251:258	pathogenic bacteria colonization and further biofilm formation	240:301	pathogenic bacteria colonization and further biofilm formation	240:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	9	2	theme	environmentally	1727:1741	arg1	method					1764:1769	the versatile and environmentally friendly preparation method	1709:1769	the versatile and environmentally friendly preparation method	1709:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	13	3	theme	simple	2766:2771	arg1	solution					2786:2793	a simple and reliable solution	2764:2793	a simple and reliable solution to the problems associated with biofilm on surfaces	2764:2845	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	3	4	theme	biofilm	576:582	arg1	formation					584:592	biofilm formation	576:592	biofilm formation	576:592	Therefore, prevention of biofilm formation becomes a preferred strategy for solving the biofilm-associated problems.					
35961522	9	5	theme	preparation	1752:1762	arg1	method					1764:1769	the versatile and environmentally friendly preparation method	1709:1769	the versatile and environmentally friendly preparation method	1709:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	6	6	theme	biofilm	1237:1243	arg1	formation					1245:1253	biofilm formation	1237:1253	biofilm formation	1237:1253	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	12	7	theme	self-adaptive	2452:2464	arg1	way					2466:2468	a self-adaptive way	2450:2468	a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation	2450:2696	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	1	8	from	failure	322:328	arg1	applications					364:375	both biomedical and industrial applications	333:375	both biomedical and industrial applications	333:375	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	6	9	theme	related	1226:1232	arg1	systems					1218:1224	systems	1218:1224	systems related to biofilm formation	1218:1253	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	3	10	theme	preferred	604:612	arg1	strategy					614:621	a preferred strategy	602:621	a preferred strategy for solving the biofilm-associated problems	602:665	Therefore, prevention of biofilm formation becomes a preferred strategy for solving the biofilm-associated problems.					
35961522	1	11	theme	materials	204:212	arg1	Surfaces					182:189	Surfaces	182:189	Surfaces of synthetic materials	182:212	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	5	12	with	acid	1007:1010	arg1	property					1031:1038	anti-adhesion property	1017:1038	anti-adhesion property	1017:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	8	13	with	coating	1459:1465	arg1	property					1493:1500	enhanced antibiofilm property	1472:1500	enhanced antibiofilm property against the biofilm formation	1472:1530	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	5	14	theme	chitosan	891:898	arg1	layer					987:991	a topmost layer	977:991	a topmost layer of hyaluronic acid with anti-adhesion property	977:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	5	14	theme	chitosan	891:898	arg1	multilayers					864:874	multilayers	864:874	multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property	864:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	9	15	theme	negligible	1791:1800	arg1	cytotoxicity					1802:1813	negligible cytotoxicity	1791:1813	negligible cytotoxicity	1791:1813	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	8	16	theme	biofilm	1514:1520	arg1	formation					1522:1530	the biofilm formation	1510:1530	the biofilm formation	1510:1530	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	10	17	theme	established	2089:2099	arg1	biofilms					2101:2108	the established biofilms	2085:2108	the established biofilms	2085:2108	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	0	18	theme	biofilm	137:143	arg1	formation					145:153	biofilm formation	137:153	biofilm formation of Pseudomonas aeruginosa	137:179	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	13	19	theme	antibiofilm	2726:2736	arg1	performance					2738:2748	improved antibiofilm performance	2717:2748	improved antibiofilm performance	2717:2748	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	5	20	theme	bactericidal	905:916	arg1	property					918:925	bactericidal property	905:925	bactericidal property	905:925	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	1	21	dep	bacteria	251:258	arg1	colonization					260:271	colonization	260:271	colonization	260:271	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	21	dep	bacteria	251:258	arg1	formation					293:301	further biofilm formation	277:301	further biofilm formation	277:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	21	dep	bacteria	251:258	arg1	bacteria					251:258	pathogenic bacteria colonization and further biofilm formation	240:301	pathogenic bacteria colonization and further biofilm formation	240:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	12	22	with	materials	2338:2346	arg1	properties					2406:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	5	23	theme	topmost	979:985	arg1	layer					987:991	a topmost layer	977:991	a topmost layer of hyaluronic acid with anti-adhesion property	977:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	12	24	theme	sensing	2398:2404	arg1	properties					2406:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	8	25	theme	long-term	1376:1384	arg1	experiments					1398:1408	long-term antibiofilm experiments	1376:1408	long-term antibiofilm experiments	1376:1408	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	0	26	theme	aeruginosa	170:179	arg1	formation					145:153	biofilm formation	137:153	biofilm formation of Pseudomonas aeruginosa	137:179	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	10	27	theme	Pathogenic	1935:1944	arg1	biofilms					1946:1953	Pathogenic biofilms	1935:1953	Pathogenic biofilms formed on the surfaces of medical devices and materials	1935:2009	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	4	28	theme	aeruginosa	777:786	arg1	formation					752:760	biofilm formation	744:760	biofilm formation of Pseudomonas aeruginosa	744:786	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	13	29	from	biofilm	2827:2833	arg1	surfaces					2838:2845	surfaces	2838:2845	surfaces	2838:2845	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	13	30	theme	reliable	2777:2784	arg1	solution					2786:2793	a simple and reliable solution	2764:2793	a simple and reliable solution to the problems associated with biofilm on surfaces	2764:2845	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	1	31	theme	industrial	353:362	arg1	applications					364:375	both biomedical and industrial applications	333:375	both biomedical and industrial applications	333:375	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	10	32	theme	SIGNIFICANCE	1921:1932	arg1	STATEMENT					1908:1916	STATEMENT	1908:1916	STATEMENT OF SIGNIFICANCE	1908:1932	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	5	33	theme	sensing	956:962	arg1	property					964:971	anti-quorum sensing property	944:971	anti-quorum sensing property	944:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	2	34	theme	chemical	506:513	arg1	composition					515:525	chemical composition	506:525	chemical composition	506:525	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	12	35	theme	bactericidal	2368:2379	arg1	properties					2406:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	4	36	theme	biofilm	744:750	arg1	formation					752:760	biofilm formation	744:760	biofilm formation of Pseudomonas aeruginosa	744:786	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	7	37	theme	experiments	1296:1306	arg1	results					1260:1266	The results	1256:1266	The results of short-term antibacterial experiments	1256:1306	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	7	38	theme	short-term	1271:1280	arg1	experiments					1296:1306	short-term antibacterial experiments	1271:1306	short-term antibacterial experiments	1271:1306	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	13	39	with	coating	2704:2710	arg1	performance					2738:2748	improved antibiofilm performance	2717:2748	improved antibiofilm performance	2717:2748	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	2	40	theme	structure	540:548	arg1	complexity					492:501	the complexity	488:501	the complexity of chemical composition and physical structure	488:548	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	8	41	theme	bacterial	1575:1583	arg1	proliferation					1585:1597	bacterial proliferation	1575:1597	bacterial proliferation	1575:1597	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	12	42	theme	natural	2330:2336	arg1	materials					2338:2346	three natural materials	2324:2346	three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties	2324:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	0	43	theme	sensing	103:109	arg1	properties					111:120	anti-quorum sensing properties	91:120	anti-quorum sensing properties	91:120	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	6	44	theme	initial	1098:1104	arg1	adhesion					1106:1113	initial adhesion	1098:1113	initial adhesion of a majority of bacteria	1098:1139	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	9	45	theme	applications	1894:1905	arg1	variety					1872:1878	a variety	1870:1878	a variety of biomedical applications	1870:1905	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	9	45	theme	applications	1894:1905	arg1	applications					1894:1905	biomedical applications	1883:1905	biomedical applications	1883:1905	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	12	46	theme	anti-adhesive	2353:2365	arg1	properties					2406:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	8	47	theme	"	1439:1439	arg1	design					1441:1446	this "three lines of defense" design	1411:1446	this "three lines of defense" design	1411:1446	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	13	48	theme	improved	2717:2724	arg1	performance					2738:2748	improved antibiofilm performance	2717:2748	improved antibiofilm performance	2717:2748	This coating with improved antibiofilm performance might provide a simple and reliable solution to the problems associated with biofilm on surfaces.					
35961522	5	49	theme	acid	1007:1010	arg1	layer					987:991	a topmost layer	977:991	a topmost layer of hyaluronic acid with anti-adhesion property	977:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	5	49	theme	acid	1007:1010	arg1	multilayers					864:874	multilayers	864:874	multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property	864:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	6	50	theme	bacteria	1132:1139	arg1	majority					1120:1127	a majority	1118:1127	a majority of bacteria	1118:1139	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	11	51	theme	diverse	2244:2250	arg1	substrates					2252:2261	diverse substrates	2244:2261	diverse substrates	2244:2261	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	12	52	theme	initial	2537:2543	arg1	adhesion					2555:2562	initial bacterial adhesion	2537:2562	initial bacterial adhesion	2537:2562	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	1	53	theme	device	315:320	arg1	failure					322:328	device failure	315:328	device failure in both biomedical and industrial applications	315:375	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	5	54	theme	anti-adhesion	1017:1029	arg1	property					1031:1038	anti-adhesion property	1017:1038	anti-adhesion property	1017:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	6	55	theme	majority	1120:1127	arg1	adhesion					1106:1113	initial adhesion	1098:1113	initial adhesion of a majority of bacteria	1098:1139	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	11	56	theme	versatile	2280:2288	arg1	method					2290:2295	a simple and versatile method	2267:2295	a simple and versatile method	2267:2295	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	8	57	theme	biomass	1614:1620	arg1	production					1622:1631	biomass production	1614:1631	biomass production	1614:1631	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	9	58	theme	building	1662:1669	arg1	blocks					1671:1676	the natural building blocks	1650:1676	the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method	1650:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	11	59	theme	simple	2269:2274	arg1	method					2290:2295	a simple and versatile method	2267:2295	a simple and versatile method	2267:2295	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	12	60	theme	biofilm	2505:2511	arg1	formation					2513:2521	biofilm formation	2505:2521	biofilm formation	2505:2521	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	2	61	theme	composition	515:525	arg1	complexity					492:501	the complexity	488:501	the complexity of chemical composition and physical structure	488:548	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	8	62	theme	enhanced	1472:1479	arg1	property					1493:1500	enhanced antibiofilm property	1472:1500	enhanced antibiofilm property against the biofilm formation	1472:1530	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	2	63	theme	Complete	378:385	arg1	elimination					387:397	Complete elimination	378:397	Complete elimination of the mature biofilms formed on the surfaces	378:443	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	0	64	theme	multifunctional	26:40	arg1	coating					42:48	A multifunctional coating	24:48	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.	0:180	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	1	65	theme	biomedical	338:347	arg1	applications					364:375	both biomedical and industrial applications	333:375	both biomedical and industrial applications	333:375	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	7	66	theme	live	1358:1361	arg1	bacteria					1363:1370	attached live bacteria	1349:1370	attached live bacteria	1349:1370	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	10	67	theme	devices	1989:1995	arg1	surfaces					1969:1976	the surfaces	1965:1976	the surfaces of medical devices and materials	1965:2009	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	1	68	theme	pathogenic	240:249	arg1	colonization					260:271	colonization	260:271	colonization	260:271	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	68	theme	pathogenic	240:249	arg1	formation					293:301	further biofilm formation	277:301	further biofilm formation	277:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	68	theme	pathogenic	240:249	arg1	bacteria					251:258	pathogenic bacteria colonization and further biofilm formation	240:301	pathogenic bacteria colonization and further biofilm formation	240:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	4	69	theme	defense	725:731	arg1	lines					716:720	three lines	710:720	three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa	710:786	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	12	70	theme	biofilm	2679:2685	arg1	maturation					2687:2696	biofilm maturation	2679:2696	biofilm maturation	2679:2696	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	2	71	theme	mature	406:411	arg1	biofilms					413:420	the mature biofilms	402:420	the mature biofilms formed on the surfaces	402:443	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	6	72	theme	attached	1160:1167	arg1	bacteria					1169:1176	the attached bacteria	1156:1176	the attached bacteria	1156:1176	The substrate deposited with this coating could suppress initial adhesion of a majority of bacteria, and then kill the attached bacteria and interfere with their quorum sensing systems related to biofilm formation.					
35961522	1	73	theme	further	277:283	arg1	formation					293:301	further biofilm formation	277:301	further biofilm formation	277:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	1	73	theme	further	277:283	arg1	bacteria					251:258	pathogenic bacteria colonization and further biofilm formation	240:301	pathogenic bacteria colonization and further biofilm formation	240:301	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	12	74	theme	formation	2513:2521	arg1	stages					2495:2500	the sequential stages	2480:2500	the sequential stages of biofilm formation	2480:2521	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	9	75	with	blocks	1671:1676	arg1	method					1764:1769	the versatile and environmentally friendly preparation method	1709:1769	the versatile and environmentally friendly preparation method	1709:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	9	75	with	blocks	1671:1676	arg1	biocompatibility					1688:1703	good biocompatibility	1683:1703	good biocompatibility	1683:1703	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	10	76	theme	materials	2001:2009	arg1	surfaces					1969:1976	the surfaces	1965:1976	the surfaces of medical devices and materials	1965:2009	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	9	77	theme	friendly	1743:1750	arg1	method					1764:1769	the versatile and environmentally friendly preparation method	1709:1769	the versatile and environmentally friendly preparation method	1709:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	1	78	theme	synthetic	194:202	arg1	materials					204:212	synthetic materials	194:212	synthetic materials	194:212	Surfaces of synthetic materials are highly susceptible to pathogenic bacteria colonization and further biofilm formation, leading to device failure in both biomedical and industrial applications.					
35961522	12	79	theme	attached	2573:2580	arg1	bacteria					2582:2589	attached bacteria	2573:2589	attached bacteria	2573:2589	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	3	80	theme	formation	584:592	arg1	prevention					562:571	prevention	562:571	prevention of biofilm formation	562:592	Therefore, prevention of biofilm formation becomes a preferred strategy for solving the biofilm-associated problems.					
35961522	5	81	theme	quaternized	879:889	arg1	chitosan					891:898	quaternized chitosan	879:898	quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property	879:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	11	82	theme	antibiofilm	2135:2145	arg1	coating					2147:2153	an antibiofilm coating	2132:2153	an antibiofilm coating	2132:2153	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	12	83	theme	different	2428:2436	arg1	function					2438:2445	different function	2428:2445	different function	2428:2445	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	4	84	theme	multifunctional	678:692	arg1	coating					694:700	a multifunctional coating	676:700	a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa	676:786	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	9	85	theme	broad	1819:1823	arg1	applicability					1825:1837	broad applicability	1819:1837	broad applicability	1819:1837	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	11	86	theme	defense	2178:2184	arg1	lines					2169:2173	three lines	2163:2173	three lines of defense to prevent biofilm formation	2163:2213	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	3	87	theme	biofilm-associated	639:656	arg1	problems					658:665	the biofilm-associated problems	635:665	the biofilm-associated problems	635:665	Therefore, prevention of biofilm formation becomes a preferred strategy for solving the biofilm-associated problems.					
35961522	5	88	theme	anti-quorum	944:954	arg1	property					964:971	anti-quorum sensing property	944:971	anti-quorum sensing property	944:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	9	89	theme	great	1850:1854	arg1	potential					1856:1864	great potential	1850:1864	great potential	1850:1864	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	8	90	theme	antibiofilm	1386:1396	arg1	experiments					1398:1408	long-term antibiofilm experiments	1376:1408	long-term antibiofilm experiments	1376:1408	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	7	91	theme	antibacterial	1282:1294	arg1	experiments					1296:1306	short-term antibacterial experiments	1271:1306	short-term antibacterial experiments	1271:1306	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	12	92	theme	anti-quorum	2386:2396	arg1	properties					2406:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	anti-adhesive, bactericidal, and anti-quorum sensing properties	2353:2415	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	0	93	theme	anti-quorum	91:101	arg1	properties					111:120	anti-quorum sensing properties	91:120	anti-quorum sensing properties	91:120	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	8	94	theme	proliferation	1585:1597	arg1	%					1570:1570	98 ± 1%	1564:1570	98 ± 1% of bacterial proliferation	1564:1597	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	94	theme	proliferation	1585:1597	arg1	proliferation					1585:1597	bacterial proliferation	1575:1597	bacterial proliferation	1575:1597	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	94	theme	proliferation	1585:1597	arg1	%					1609:1609	71 ± 2%	1603:1609	71 ± 2% of biomass production	1603:1631	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	94	theme	proliferation	1585:1597	arg1	production					1622:1631	biomass production	1614:1631	biomass production	1614:1631	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	4	95	theme	simple	807:812	arg1	method					828:833	a simple and versatile method	805:833	a simple and versatile method	805:833	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	2	96	theme	physical	531:538	arg1	structure					540:548	physical structure	531:548	physical structure	531:548	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	4	97	theme	versatile	818:826	arg1	method					828:833	a simple and versatile method	805:833	a simple and versatile method	805:833	Herein, a multifunctional coating showing three lines of defense to prevent biofilm formation of Pseudomonas aeruginosa is fabricated by a simple and versatile method.					
35961522	5	98	theme	hyaluronic	996:1005	arg1	acid					1007:1010	hyaluronic acid	996:1010	hyaluronic acid with anti-adhesion property	996:1038	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	2	99	theme	great	465:469	arg1	challenge					471:479	a great challenge	463:479	a great challenge due to the complexity of chemical composition and physical structure	463:548	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	12	100	theme	bacterial	2545:2553	arg1	adhesion					2555:2562	initial bacterial adhesion	2537:2562	initial bacterial adhesion	2537:2562	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	8	101	theme	defense	1432:1438	arg1	lines					1423:1427	three lines	1417:1427	this "three lines of defense" design	1411:1446	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	2	102	theme	biofilms	413:420	arg1	elimination					387:397	Complete elimination	378:397	Complete elimination of the mature biofilms formed on the surfaces	378:443	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	0	103	theme	defense	15:21	arg1	lines					6:10	Three lines	0:10	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.	0:180	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	8	104	theme	production	1622:1631	arg1	%					1570:1570	98 ± 1%	1564:1570	98 ± 1% of bacterial proliferation	1564:1597	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	104	theme	production	1622:1631	arg1	proliferation					1585:1597	bacterial proliferation	1575:1597	bacterial proliferation	1575:1597	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	104	theme	production	1622:1631	arg1	%					1609:1609	71 ± 2%	1603:1609	71 ± 2% of biomass production	1603:1631	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	8	104	theme	production	1622:1631	arg1	production					1622:1631	biomass production	1614:1631	biomass production	1614:1631	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	9	105	theme	natural	1654:1660	arg1	blocks					1671:1676	the natural building blocks	1650:1676	the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method	1650:1769	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	7	106	theme	bacteria	1363:1370	arg1	bacteria					1363:1370	attached live bacteria	1349:1370	attached live bacteria	1349:1370	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	7	106	theme	bacteria	1363:1370	arg1	%					1344:1344	98 ± 2%	1338:1344	98 ± 2% of attached live bacteria	1338:1370	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	10	107	dep	pose	2011:2014	arg1	STATEMENT					1908:1916	STATEMENT	1908:1916	STATEMENT OF SIGNIFICANCE	1908:1932	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	5	108	with	chitosan	891:898	arg1	property					964:971	anti-quorum sensing property	944:971	anti-quorum sensing property	944:971	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	5	108	with	chitosan	891:898	arg1	acylase					931:937	acylase	931:937	acylase	931:937	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	5	108	with	chitosan	891:898	arg1	property					918:925	bactericidal property	905:925	bactericidal property	905:925	This coating is composed of multilayers of quaternized chitosan with bactericidal property and acylase with anti-quorum sensing property and a topmost layer of hyaluronic acid with anti-adhesion property.					
35961522	9	109	theme	biomedical	1883:1892	arg1	applications					1894:1905	biomedical applications	1883:1905	biomedical applications	1883:1905	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	11	110	theme	biofilm	2197:2203	arg1	formation					2205:2213	biofilm formation	2197:2213	biofilm formation	2197:2213	Herein, we developed an antibiofilm coating showing three lines of defense to prevent biofilm formation, which could be deposited on diverse substrates via a simple and versatile method.					
35961522	7	111	theme	attached	1349:1356	arg1	bacteria					1363:1370	attached live bacteria	1349:1370	attached live bacteria	1349:1370	The results of short-term antibacterial experiments show that our coating reduced 98 ± 2% of attached live bacteria.					
35961522	2	112	theme	due	481:483	arg1	challenge					471:479	a great challenge	463:479	a great challenge due to the complexity of chemical composition and physical structure	463:548	Complete elimination of the mature biofilms formed on the surfaces, however, remains a great challenge due to the complexity of chemical composition and physical structure.					
35961522	9	113	theme	good	1683:1686	arg1	biocompatibility					1688:1703	good biocompatibility	1683:1703	good biocompatibility	1683:1703	Benefiting from the natural building blocks with good biocompatibility and the versatile and environmentally friendly preparation method, this coating shows negligible cytotoxicity and broad applicability, providing great potential for a variety of biomedical applications.					
35961522	12	114	theme	bacterial	2651:2659	arg1	proliferation					2661:2673	bacterial proliferation	2651:2673	bacterial proliferation	2651:2673	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	12	115	theme	sequential	2484:2493	arg1	stages					2495:2500	the sequential stages	2480:2500	the sequential stages of biofilm formation	2480:2521	This coating was based on three natural materials with anti-adhesive, bactericidal, and anti-quorum sensing properties and showed different function in a self-adaptive way to target the sequential stages of biofilm formation by preventing initial bacterial adhesion, killing attached bacteria and interfering with their quorum sensing system to inhibit bacterial proliferation and biofilm maturation.					
35961522	8	116	theme	lines	1423:1427	arg1	design					1441:1446	this "three lines of defense" design	1411:1446	this "three lines of defense" design	1411:1446	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	10	117	theme	medical	1981:1987	arg1	devices					1989:1995	medical devices	1981:1995	medical devices	1981:1995	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
35961522	8	118	theme	antibiofilm	1481:1491	arg1	property					1493:1500	enhanced antibiofilm property	1472:1500	enhanced antibiofilm property against the biofilm formation	1472:1530	In long-term antibiofilm experiments, this "three lines of defense" design endows the coating with enhanced antibiofilm property against the biofilm formation for at least 3 days by reducing 98 ± 1% of bacterial proliferation and 71 ± 2% of biomass production.					
35961522	0	119	with	coating	42:48	arg1	bacteria-killing					70:85	bacteria-killing	70:85	bacteria-killing	70:85	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	0	119	with	coating	42:48	arg1	anti-adhesion					55:67	anti-adhesion	55:67	anti-adhesion	55:67	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	0	119	with	coating	42:48	arg1	properties					111:120	anti-quorum sensing properties	91:120	anti-quorum sensing properties	91:120	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	0	120	dep	lines	6:10	arg1	coating					42:48	A multifunctional coating	24:48	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.	0:180	Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa.					
35961522	10	121	theme	urgent	2019:2024	arg1	problem					2026:2032	an urgent problem	2016:2032	an urgent problem	2016:2032	STATEMENT OF SIGNIFICANCE: Pathogenic biofilms formed on the surfaces of medical devices and materials pose an urgent problem, and it remains challenging to treat and eradicate the established biofilms.					
36773266	7	0	theme	donor-acceptor	1396:1409	arg1	interactions					1411:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	4	1	theme	BET	631:633	arg1	measurements					635:646	BET measurements	631:646	BET measurements	631:646	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	7	2	dep	results	1284:1290	arg1	postulated					1292:1301	postulated	1292:1301	results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions	1284:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	1	3	theme	Water	140:144	arg1	affair					170:175	a dreadful affair	159:175	a dreadful affair that has incessantly aggravated, exposing our planet to danger	159:238	Water pollution is a dreadful affair that has incessantly aggravated, exposing our planet to danger.					
36773266	1	3	theme	Water	140:144	arg1	pollution					146:154	Water pollution	140:154	Water pollution	140:154	Water pollution is a dreadful affair that has incessantly aggravated, exposing our planet to danger.					
36773266	8	4	theme	viable	1562:1567	arg1	applicability					1569:1581	its viable applicability	1558:1581	its viable applicability	1558:1581	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	8	4	theme	viable	1562:1567	arg1	efficient					1589:1597	efficient	1589:1597	efficient	1589:1597	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	6	5	theme	pseudo-second-order	990:1008	arg1	model					1018:1022	pseudo-second-order kinetic model	990:1022	pseudo-second-order kinetic model	990:1022	The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin.					
36773266	2	6	theme	persistent	260:269	arg1	compound					286:293	the persistent nitro aromatic compound	256:293	the persistent nitro aromatic compound like nitrophenols	256:311	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	0	7	theme	process	82:88	arg1	optimization					90:101	process optimization	82:101	process optimization	82:101	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	7	8	theme	π-π	1366:1368	arg1	interaction					1370:1380	π-π interaction	1366:1380	π-π interaction	1366:1380	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	2	9	theme	researchers	335:345	arg1	difficulty					408:417	the researchers due to their hazardous impacts, excessive usage, and removal difficulty	331:417	the researchers due to their hazardous impacts, excessive usage, and removal difficulty	331:417	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	8	10	theme	good	1484:1487	arg1	characteristics					1500:1514	good adsorption characteristics	1484:1514	good adsorption characteristics	1484:1514	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	5	11	with	composite	899:907	arg1	performance					938:948	an excellent adsorption performance	914:948	an excellent adsorption performance toward o-NP	914:960	The comparison study pointed out the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP.					
36773266	7	12	theme	interaction	1370:1380	arg1	interactions					1411:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	4	13	theme	magnetic	760:767	arg1	property					769:776	its excellent magnetic property	746:776	its excellent magnetic property (20.34 emu/g)	746:790	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	4	13	theme	magnetic	760:767	arg1	20.34 emu/g					779:789	20.34 emu/g	779:789	20.34 emu/g	779:789	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	7	14	theme	qmax reached	1219:1230	arg1	320.26 mg/g					1232:1242	the computed qmax reached 320.26 mg/g	1206:1242	the computed qmax reached 320.26 mg/g at pH 6 and 25 °C.	1206:1261	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	7	15	theme	pf	1333:1334	arg1	o-NP					1336:1339	the adsorption mechanism pf o-NP	1308:1339	the adsorption mechanism pf o-NP	1308:1339	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	1	16	theme	dreadful	161:168	arg1	affair					170:175	a dreadful affair	159:175	a dreadful affair that has incessantly aggravated, exposing our planet to danger	159:238	Water pollution is a dreadful affair that has incessantly aggravated, exposing our planet to danger.					
36773266	1	16	theme	dreadful	161:168	arg1	pollution					146:154	Water pollution	140:154	Water pollution	140:154	Water pollution is a dreadful affair that has incessantly aggravated, exposing our planet to danger.					
36773266	7	17	theme	H-bonding	1355:1363	arg1	interactions					1411:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	H-bonding, π-π interaction, and electron donor-acceptor interactions	1355:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	4	18	theme	excellent	750:758	arg1	property					769:776	its excellent magnetic property	746:776	its excellent magnetic property (20.34 emu/g)	746:790	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	4	18	theme	excellent	750:758	arg1	20.34 emu/g					779:789	20.34 emu/g	779:789	20.34 emu/g	779:789	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	8	19	theme	aromatic	1659:1666	arg1	pollutants					1668:1677	nitro aromatic pollutants	1653:1677	nitro aromatic pollutants	1653:1677	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	6	20	theme	adsorption	967:976	arg1	data					978:981	The adsorption data	963:981	The adsorption data	963:981	The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin.					
36773266	8	21	theme	Ti	1461:1462	arg1	composite					1465:1473	Fe3O4-κ-Carr/MIL-125(Ti) composite	1440:1473	Fe3O4-κ-Carr/MIL-125(Ti) composite	1440:1473	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	7	22	theme	adsorption	1312:1321	arg1	o-NP					1336:1339	the adsorption mechanism pf o-NP	1308:1339	the adsorption mechanism pf o-NP	1308:1339	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	8	23	theme	nitro	1653:1657	arg1	pollutants					1668:1677	nitro aromatic pollutants	1653:1677	nitro aromatic pollutants	1653:1677	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	2	24	theme	hazardous	360:368	arg1	impacts					370:376	their hazardous impacts	354:376	their hazardous impacts	354:376	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	4	25	theme	surface	666:672	arg1	area					674:677	the high surface area	657:677	the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g	657:726	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	7	26	theme	mechanism	1323:1331	arg1	o-NP					1336:1339	the adsorption mechanism pf o-NP	1308:1339	the adsorption mechanism pf o-NP	1308:1339	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	7	27	from	25 °C.	1256:1261	arg1	320.26 mg/g					1232:1242	the computed qmax reached 320.26 mg/g	1206:1242	the computed qmax reached 320.26 mg/g at pH 6 and 25 °C.	1206:1261	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	2	28	theme	aromatic	277:284	arg1	compound					286:293	the persistent nitro aromatic compound	256:293	the persistent nitro aromatic compound like nitrophenols	256:311	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	7	29	theme	computed	1210:1217	arg1	320.26 mg/g					1232:1242	the computed qmax reached 320.26 mg/g	1206:1242	the computed qmax reached 320.26 mg/g at pH 6 and 25 °C.	1206:1261	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	0	30	theme	nitrophenol	14:24	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.	0:138	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	8	31	theme	adsorption	1489:1498	arg1	characteristics					1500:1514	good adsorption characteristics	1484:1514	good adsorption characteristics	1484:1514	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	2	32	theme	nitro	271:275	arg1	compound					286:293	the persistent nitro aromatic compound	256:293	the persistent nitro aromatic compound like nitrophenols	256:311	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	7	33	theme	o-NP	1165:1168	arg1	capacity					1153:1160	the supreme adsorption capacity	1130:1160	the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions	1130:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	0	34	theme	novel	33:37	arg1	composite					71:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	6	35	theme	Freundlich	1029:1038	arg1	model					1049:1053	Freundlich isotherm model	1029:1053	Freundlich isotherm model	1029:1053	The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin.					
36773266	4	36	theme	m2/g	723:726	arg1	m2/g					723:726	about 163.27 m2/g	710:726	about 163.27 m2/g	710:726	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	4	36	theme	m2/g	723:726	arg1	Ti					703:704	Ti	703:704	Ti	703:704	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	4	36	theme	m2/g	723:726	arg1	Fe3O4-κ-Carr/MIL-125					682:701	Fe3O4-κ-Carr/MIL-125	682:701	Fe3O4-κ-Carr/MIL-125	682:701	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	3	37	theme	efficient	562:570	arg1	removal					583:589	efficient adsorptive removal	562:589	efficient adsorptive removal of o-nitrophenol (o-NP)	562:613	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	2	38	theme	excessive	379:387	arg1	usage					389:393	excessive usage	379:393	excessive usage	379:393	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36773266	3	39	theme	adsorptive	572:581	arg1	removal					583:589	efficient adsorptive removal	562:589	efficient adsorptive removal of o-nitrophenol (o-NP)	562:613	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	6	40	theme	isotherm	1040:1047	arg1	model					1049:1053	Freundlich isotherm model	1029:1053	Freundlich isotherm model	1029:1053	The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin.					
36773266	0	41	theme	Fe3O4-κ-carrageenan/MIL-125	39:65	arg1	composite					71:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	5	42	theme	adsorption	927:936	arg1	performance					938:948	an excellent adsorption performance	914:948	an excellent adsorption performance toward o-NP	914:960	The comparison study pointed out the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP.					
36773266	5	43	theme	excellent	917:925	arg1	performance					938:948	an excellent adsorption performance	914:948	an excellent adsorption performance toward o-NP	914:960	The comparison study pointed out the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP.					
36773266	5	44	theme	synergistic	830:840	arg1	effect					842:847	the synergistic effect	826:847	the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti)	826:886	The comparison study pointed out the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP.					
36773266	0	45	dep	Adsorption	0:9	arg1	optimization					90:101	process optimization	82:101	process optimization	82:101	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	0	45	dep	Adsorption	0:9	arg1	kinetics					115:122	kinetics	115:122	kinetics	115:122	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	0	45	dep	Adsorption	0:9	arg1	mechanism					129:137	mechanism	129:137	mechanism	129:137	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	0	45	dep	Adsorption	0:9	arg1	isotherms					104:112	isotherms	104:112	isotherms	104:112	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	3	46	theme	novel	440:444	arg1	composite					461:469	a novel multi-featured composite	438:469	a novel multi-featured composite	438:469	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	4	47	theme	Fe3O4-κ-Carr/MIL-125	682:701	arg1	area					674:677	the high surface area	657:677	the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g	657:726	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	8	48	theme	Fe3O4-κ-Carr/MIL-125	1440:1459	arg1	composite					1465:1473	Fe3O4-κ-Carr/MIL-125(Ti) composite	1440:1473	Fe3O4-κ-Carr/MIL-125(Ti) composite	1440:1473	Interestingly, Fe3O4-κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.					
36773266	3	49	theme	o-nitrophenol	594:606	arg1	removal					583:589	efficient adsorptive removal	562:589	efficient adsorptive removal of o-nitrophenol (o-NP)	562:613	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	7	50	dep	Fe3O4-κ-Carr/MIL-125	1175:1194	arg1	results					1284:1290	results	1284:1290	results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions	1284:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	3	51	theme	multi-featured	446:459	arg1	composite					461:469	a novel multi-featured composite	438:469	a novel multi-featured composite	438:469	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	4	52	theme	high	661:664	arg1	area					674:677	the high surface area	657:677	the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g	657:726	Interestingly, BET measurements revealed the high surface area of Fe3O4-κ-Carr/MIL-125(Ti) of about 163.27 m2/g, while VSM showed its excellent magnetic property (20.34 emu/g).					
36773266	7	53	theme	supreme	1134:1140	arg1	capacity					1153:1160	the supreme adsorption capacity	1130:1160	the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions	1130:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	6	54	theme	kinetic	1010:1016	arg1	model					1018:1022	pseudo-second-order kinetic model	990:1022	pseudo-second-order kinetic model	990:1022	The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin.					
36773266	5	55	theme	comparison	797:806	arg1	study					808:812	The comparison study	793:812	The comparison study	793:812	The comparison study pointed out the synergistic effect between Fe3O4, κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP.					
36773266	7	56	theme	adsorption	1142:1151	arg1	capacity					1153:1160	the supreme adsorption capacity	1130:1160	the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions	1130:1422	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	0	57	theme	Ti	67:68	arg1	composite					71:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite	31:79	Adsorption of nitrophenol onto a novel Fe3O4-κ-carrageenan/MIL-125(Ti) composite: process optimization, isotherms, kinetics, and mechanism.					
36773266	3	58	theme	magnetic	543:550	arg1	Fe3O4					552:556	magnetic Fe3O4	543:556	magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP)	543:613	For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe3O4 for efficient adsorptive removal of o-nitrophenol (o-NP).					
36773266	7	59	from	pH	1247:1248	arg1	320.26 mg/g					1232:1242	the computed qmax reached 320.26 mg/g	1206:1242	the computed qmax reached 320.26 mg/g at pH 6 and 25 °C.	1206:1261	Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe3O4-κ-Carr/MIL-125(Ti) since the computed qmax reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π-π interaction, and electron donor-acceptor interactions.					
36773266	2	60	theme	due	347:349	arg1	difficulty					408:417	the researchers due to their hazardous impacts, excessive usage, and removal difficulty	331:417	the researchers due to their hazardous impacts, excessive usage, and removal difficulty	331:417	In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty.					
36596152	4	0	theme	starch	755:760	arg1	ΔH					794:795	ΔH	794:795	ΔH	794:795	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	4	0	theme	starch	755:760	arg1	change					786:791	starch gelatinization enthalpy change	755:791	starch gelatinization enthalpy change (ΔH)	755:796	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	3	1	from	order	603:607	arg1	contents					640:647	total dietary fiber contents	620:647	total dietary fiber contents	620:647	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	3	1	from	order	603:607	arg1	ash					612:614	ash	612:614	ash	612:614	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	2	2	theme	particle	270:277	arg1	sizes					279:283	The particle sizes	266:283	The particle sizes of the three generated flour streams	266:320	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	5	3	theme	comparable	1059:1068	arg1	properties					1094:1103	generally comparable foaming and emulsifying properties	1049:1103	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	4	4	theme	enthalpy	777:784	arg1	ΔH					794:795	ΔH	794:795	ΔH	794:795	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	4	4	theme	enthalpy	777:784	arg1	change					786:791	starch gelatinization enthalpy change	755:791	starch gelatinization enthalpy change (ΔH)	755:796	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	3	5	from	contents	577:584	arg1	order					517:521	the same rank order	503:521	the same rank order of fine > whole > coarse in starch and damaged-starch contents	503:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	3	6	theme	dietary	626:632	arg1	contents					640:647	total dietary fiber contents	620:647	total dietary fiber contents	620:647	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	6	7	from	trend	1472:1476	arg1	flours					1492:1497	the cereal flours	1481:1497	the cereal flours	1481:1497	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	7	from	trend	1472:1476	arg1	attributable					1522:1533	attributable	1522:1533	attributable	1522:1533	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	8	theme	fine > whole > coarse	1370:1390	arg1	order					1361:1365	a descending order	1348:1365	a descending order of fine > whole > coarse	1348:1390	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	1	9	theme	cereal	147:152	arg1	barley					155:160	barley	155:160	barley	155:160	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	1	9	theme	cereal	147:152	arg1	seeds					169:173	cereal (barley, oats) seeds	147:173	cereal (barley, oats) seeds	147:173	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	3	10	theme	rank	512:515	arg1	order					517:521	the same rank order	503:521	the same rank order of fine > whole > coarse in starch and damaged-starch contents	503:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	7	11	theme	cereal	1832:1837	arg1	flours					1839:1844	cereal flours	1832:1844	cereal flours	1832:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	5	12	theme	flour	910:914	arg1	streams					916:922	the three flour streams	900:922	the three flour streams	900:922	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	2	13	with	consistent	376:385	arg1	observation					396:406	the observation	392:406	the observation	392:406	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	4	14	theme	functional	662:671	arg1	properties					673:682	those functional properties	656:682	those functional properties closely related to starch occurring in flour	656:727	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	6	15	theme	flours	1432:1437	arg1	viscosities					1407:1417	the pasting viscosities	1395:1417	the pasting viscosities of the pulse flours	1395:1437	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	16	theme	foaming	1070:1076	arg1	properties					1094:1103	generally comparable foaming and emulsifying properties	1049:1103	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	1	17	theme	fine	253:256	arg1	flours					258:263	coarse and fine flours	242:263	coarse and fine flours	242:263	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	2	18	theme	electron	423:430	arg1	microscopy					432:441	scanning electron microscopy	414:441	scanning electron microscopy (SEM)	414:447	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	2	18	theme	electron	423:430	arg1	SEM					444:446	SEM	444:446	SEM	444:446	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	6	19	theme	pulse	1582:1586	arg1	flours					1629:1634	their corresponding flours	1609:1634	their corresponding flours	1609:1634	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	19	theme	pulse	1582:1586	arg1	structures					1564:1573	the different microscopic structures	1538:1573	the different microscopic structures of the pulse and cereal seeds	1538:1603	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	20	theme	streams	1118:1124	arg1	properties					1094:1103	generally comparable foaming and emulsifying properties	1049:1103	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	20	theme	streams	1118:1124	arg1	order					1156:1160	an order	1153:1160	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	21	theme	coarse > whole > fine	977:997	arg1	trend					968:972	a trend	966:972	a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively	966:1246	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	6	22	theme	cereal	1485:1490	arg1	flours					1492:1497	the cereal flours	1481:1497	the cereal flours	1481:1497	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	22	theme	cereal	1485:1490	arg1	attributable					1522:1533	attributable	1522:1533	attributable	1522:1533	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	23	theme	pulse	1129:1133	arg1	flours					1135:1140	pulse flours	1129:1140	pulse flours	1129:1140	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	4	24	theme	same	830:833	arg1	order					835:839	the same order	826:839	the same order of fine > whole > coarse	826:864	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	6	25	theme	microscopic	1552:1562	arg1	structures					1564:1573	the different microscopic structures	1538:1573	the different microscopic structures of the pulse and cereal seeds	1538:1603	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	26	theme	oil-binding	1190:1200	arg1	OBC					1212:1214	OBC	1212:1214	OBC	1212:1214	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	26	theme	oil-binding	1190:1200	arg1	capacity					1202:1209	oil-binding capacity	1190:1209	oil-binding capacity (OBC) of cereal flours, respectively	1190:1246	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	2	27	theme	streams	314:320	arg1	sizes					279:283	The particle sizes	266:283	The particle sizes of the three generated flour streams	266:320	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	7	28	theme	techno-functional	1790:1806	arg1	properties					1808:1817	the specific techno-functional properties	1777:1817	the specific techno-functional properties of pulse and cereal flours	1777:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	6	29	theme	clear	1466:1470	arg1	trend					1472:1476	a clear trend	1464:1476	a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours	1464:1634	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	2	30	theme	consistent	376:385	arg1	order					344:348	a descending order	331:348	a descending order	331:348	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	2	31	theme	generated	298:306	arg1	streams					314:320	the three generated flour streams	288:320	the three generated flour streams	288:320	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	2	32	theme	coarse > whole > fine	353:373	arg1	order					344:348	a descending order	331:348	a descending order	331:348	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	1	33	dep	pulse	123:127	arg1	lentil					135:140	lentil	135:140	lentil	135:140	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	1	33	dep	pulse	123:127	arg1	pea					130:132	pea	130:132	pea	130:132	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	0	34	theme	differential	12:23	arg1	sieving					25:31	differential sieving	12:31	differential sieving	12:31	Milling and differential sieving to diversify flour functionality: A comparison between pulses and cereals.					
36596152	6	35	theme	corresponding	1615:1627	arg1	flours					1629:1634	their corresponding flours	1609:1634	their corresponding flours	1609:1634	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	36	theme	coarse > whole > fine	1165:1185	arg1	properties					1094:1103	generally comparable foaming and emulsifying properties	1049:1103	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	36	theme	coarse > whole > fine	1165:1185	arg1	order					1156:1160	an order	1153:1160	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	6	37	theme	particle	1263:1270	arg1	sizes					1272:1276	different particle sizes	1253:1276	different particle sizes	1253:1276	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	4	38	theme	L	738:738	arg1	brightness					742:751	brightness	742:751	brightness	742:751	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	4	38	theme	L	738:738	arg1	*					739:739	L*	738:739	L* (brightness)	738:752	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	0	39	theme	flour	46:50	arg1	functionality					52:64	flour functionality	46:64	flour functionality	46:64	Milling and differential sieving to diversify flour functionality: A comparison between pulses and cereals.					
36596152	1	40	theme	coarse	242:247	arg1	flours					258:263	coarse and fine flours	242:263	coarse and fine flours	242:263	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	7	41	theme	microscopic	1718:1728	arg1	structure					1730:1738	microscopic structure	1718:1738	microscopic structure	1718:1738	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	7	42	theme	particle	1677:1684	arg1	size					1686:1689	particle size	1677:1689	particle size	1677:1689	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	6	43	theme	cereal	1592:1597	arg1	seeds					1599:1603	cereal seeds	1592:1603	cereal seeds	1592:1603	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	44	theme	emulsifying	1082:1092	arg1	properties					1094:1103	generally comparable foaming and emulsifying properties	1049:1103	generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine	1049:1185	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	6	45	theme	different	1253:1261	arg1	sizes					1272:1276	different particle sizes	1253:1276	different particle sizes	1253:1276	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	5	46	theme	protein	880:886	arg1	contents					888:895	protein contents	880:895	protein contents of the three flour streams	880:922	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	3	47	theme	total	620:624	arg1	contents					640:647	total dietary fiber contents	620:647	total dietary fiber contents	620:647	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	5	48	theme	cereal	1220:1225	arg1	flours					1227:1232	cereal flours	1220:1232	cereal flours	1220:1232	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	6	49	theme	flour	1317:1321	arg1	streams					1323:1329	the three flour streams only	1307:1334	the three flour streams only	1307:1334	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	1	50	theme	whole	200:204	arg1	flours					206:211	whole flours	200:211	whole flours	200:211	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	4	51	theme	gelatinization	762:775	arg1	ΔH					794:795	ΔH	794:795	ΔH	794:795	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	4	51	theme	gelatinization	762:775	arg1	change					786:791	starch gelatinization enthalpy change	755:791	starch gelatinization enthalpy change (ΔH)	755:796	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	6	52	theme	pasting	1399:1405	arg1	viscosities					1407:1417	the pasting viscosities	1395:1417	the pasting viscosities of the pulse flours	1395:1437	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	3	53	theme	fiber	634:638	arg1	contents					640:647	total dietary fiber contents	620:647	total dietary fiber contents	620:647	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	3	54	theme	flour	482:486	arg1	streams					488:494	the three flour streams	472:494	the three flour streams	472:494	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	3	55	theme	same	507:510	arg1	order					517:521	the same rank order	503:521	the same rank order of fine > whole > coarse in starch and damaged-starch contents	503:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	6	56	theme	descending	1350:1359	arg1	order					1361:1365	a descending order	1348:1365	a descending order of fine > whole > coarse	1348:1390	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	4	57	dep	such	730:733	arg1	as					735:736	as	735:736	as	735:736	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	4	58	theme	gel	803:805	arg1	hardness					807:814	gel hardness	803:814	gel hardness	803:814	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	7	59	theme	flours	1839:1844	arg1	properties					1808:1817	the specific techno-functional properties	1777:1817	the specific techno-functional properties of pulse and cereal flours	1777:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	5	60	theme	flours	1135:1140	arg1	streams					1118:1124	the three streams	1108:1124	the three streams of pulse flours	1108:1140	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	61	theme	streams	916:922	arg1	contents					888:895	protein contents	880:895	protein contents of the three flour streams	880:922	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	3	62	theme	fine > whole > coarse	526:546	arg1	order					517:521	the same rank order	503:521	the same rank order of fine > whole > coarse in starch and damaged-starch contents	503:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	6	63	theme	pulse	1426:1430	arg1	flours					1432:1437	the pulse flours	1422:1437	the pulse flours	1422:1437	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	7	64	theme	pulse	1822:1826	arg1	properties					1808:1817	the specific techno-functional properties	1777:1817	the specific techno-functional properties of pulse and cereal flours	1777:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	2	65	theme	scanning	414:421	arg1	microscopy					432:441	scanning electron microscopy	414:441	scanning electron microscopy (SEM)	414:447	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	2	65	theme	scanning	414:421	arg1	SEM					444:446	SEM	444:446	SEM	444:446	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	3	66	from	order	517:521	arg1	contents					577:584	starch and damaged-starch contents	551:584	starch and damaged-starch contents	551:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	7	67	theme	specific	1781:1788	arg1	properties					1808:1817	the specific techno-functional properties	1777:1817	the specific techno-functional properties of pulse and cereal flours	1777:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	6	68	theme	different	1542:1550	arg1	structures					1564:1573	the different microscopic structures	1538:1573	the different microscopic structures of the pulse and cereal seeds	1538:1603	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	4	69	theme	related	692:698	arg1	properties					673:682	those functional properties	656:682	those functional properties closely related to starch occurring in flour	656:727	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	3	70	from	fine > whole > coarse	526:546	arg1	contents					577:584	starch and damaged-starch contents	551:584	starch and damaged-starch contents	551:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	2	71	theme	flour	308:312	arg1	streams					314:320	the three generated flour streams	288:320	the three generated flour streams	288:320	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	6	72	theme	chemical	1282:1289	arg1	compositions					1291:1302	chemical compositions	1282:1302	chemical compositions	1282:1302	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	7	73	theme	important	1745:1753	arg1	variables					1755:1763	important variables	1745:1763	important variables determining the specific techno-functional properties of pulse and cereal flours	1745:1844	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	3	74	theme	damaged-starch	562:575	arg1	contents					577:584	starch and damaged-starch contents	551:584	starch and damaged-starch contents	551:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	2	75	theme	descending	333:342	arg1	order					344:348	a descending order	331:348	a descending order	331:348	The particle sizes of the three generated flour streams followed a descending order of coarse > whole > fine, consistent with the observation under scanning electron microscopy (SEM).					
36596152	6	76	dep	sizes	1272:1276	arg1	The					1249:1251	The	1249:1251	The	1249:1251	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	4	77	theme	fine > whole > coarse	844:864	arg1	order					835:839	the same order	826:839	the same order of fine > whole > coarse	826:864	Thus, those functional properties closely related to starch occurring in flour, such as L* (brightness), starch gelatinization enthalpy change (ΔH), and gel hardness, followed the same order of fine > whole > coarse.					
36596152	3	78	theme	starch	551:556	arg1	contents					577:584	starch and damaged-starch contents	551:584	starch and damaged-starch contents	551:584	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	5	79	theme	flours	1227:1232	arg1	OBC					1212:1214	OBC	1212:1214	OBC	1212:1214	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	79	theme	flours	1227:1232	arg1	capacity					1202:1209	oil-binding capacity	1190:1209	oil-binding capacity (OBC) of cereal flours, respectively	1190:1246	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	80	from	trend	968:972	arg1	oats					1013:1016	oats	1013:1016	oats	1013:1016	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	5	80	from	trend	968:972	arg1	barley					1002:1007	barley	1002:1007	barley	1002:1007	By contrast, protein contents of the three flour streams did not vary in pea and lentil but showed a trend of coarse > whole > fine in barley and oats, which could partially explain generally comparable foaming and emulsifying properties of the three streams of pulse flours as well as an order of coarse > whole > fine in oil-binding capacity (OBC) of cereal flours, respectively.					
36596152	0	81	dep	diversify	36:44	arg1	comparison					69:78	A comparison	67:78	A comparison between pulses and cereals	67:105	Milling and differential sieving to diversify flour functionality: A comparison between pulses and cereals.					
36596152	7	82	theme	chemical	1692:1699	arg1	composition					1701:1711	chemical composition	1692:1711	chemical composition	1692:1711	This research clearly demonstrated that particle size, chemical composition, and microscopic structure were important variables determining the specific techno-functional properties of pulse and cereal flours.					
36596152	6	83	theme	seeds	1599:1603	arg1	flours					1629:1634	their corresponding flours	1609:1634	their corresponding flours	1609:1634	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	83	theme	seeds	1599:1603	arg1	structures					1564:1573	the different microscopic structures	1538:1573	the different microscopic structures of the pulse and cereal seeds	1538:1603	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	3	84	theme	opposite	594:601	arg1	order					603:607	the opposite order	590:607	the opposite order in ash and total dietary fiber contents	590:647	Among the four crops, the three flour streams showed the same rank order of fine > whole > coarse in starch and damaged-starch contents but the opposite order in ash and total dietary fiber contents.					
36596152	1	85	dep	barley	155:160	arg1	oats					163:166	oats	163:166	oats	163:166	In this study, pulse (pea, lentil) and cereal (barley, oats) seeds were firstly milled into whole flours, which were then sieved into coarse and fine flours.					
36596152	6	86	theme	streams	1323:1329	arg1	sizes					1272:1276	different particle sizes	1253:1276	different particle sizes	1253:1276	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36596152	6	86	theme	streams	1323:1329	arg1	compositions					1291:1302	chemical compositions	1282:1302	chemical compositions	1282:1302	The different particle sizes and chemical compositions of the three flour streams only resulted in a descending order of fine > whole > coarse in the pasting viscosities of the pulse flours but did not lead to such a clear trend in the cereal flours, which could be partly attributable to the different microscopic structures of the pulse and cereal seeds and their corresponding flours.					
36347373	7	0	theme	graft	1256:1260	arg1	length					1268:1273	high enough graft chain length	1244:1273	high enough graft chain length	1244:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	6	1	theme	Mechanical	939:948	arg1	tests					950:954	Mechanical tests	939:954	Mechanical tests	939:954	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	4	2	theme	Optical	666:672	arg1	transparency					674:685	Optical transparency	666:685	Optical transparency	666:685	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	1	3	theme	high	236:239	arg1	percentage					255:264	high polymer graft percentage	236:264	high polymer graft percentage	236:264	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	7	4	theme	chain	1262:1266	arg1	length					1268:1273	high enough graft chain length	1244:1273	high enough graft chain length	1244:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	3	5	theme	hot-pressing	636:647	arg1	subsequentially					649:663	simple hot-pressing subsequentially	629:663	simple hot-pressing subsequentially	629:663	The one-component composite films were manufactured by simple hot-pressing subsequentially.					
36347373	5	6	theme	morphological	912:924	arg1	observation					926:936	morphological observation	912:936	morphological observation	912:936	The uniform fracture surface confirmed the uniform dispersity by morphological observation.					
36347373	1	7	theme	polymer	241:247	arg1	percentage					255:264	high polymer graft percentage	236:264	high polymer graft percentage	236:264	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	7	8	theme	high	1244:1247	arg1	length					1268:1273	high enough graft chain length	1244:1273	high enough graft chain length	1244:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	6	9	dep	PS	1104:1105	arg1	composite					1142:1150	grafted CNF one-component composite	1116:1150	grafted CNF one-component composite	1116:1150	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	7	10	theme	thermal	1377:1383	arg1	ability					1399:1405	thermal manufacturing ability	1377:1405	thermal manufacturing ability	1377:1405	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	4	11	theme	glass	711:715	arg1	temperature					728:738	glass transition temperature	711:738	glass transition temperature	711:738	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	1	12	theme	graft	249:253	arg1	percentage					255:264	high polymer graft percentage	236:264	high polymer graft percentage	236:264	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	2	13	theme	grafted	486:492	arg1	CNFs					494:497	PMMA/PS grafted CNFs	478:497	PMMA/PS grafted CNFs	478:497	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	6	14	theme	CNF	1124:1126	arg1	composite					1142:1150	grafted CNF one-component composite	1116:1150	grafted CNF one-component composite	1116:1150	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	2	15	theme	PMMA/PS	478:484	arg1	CNFs					494:497	PMMA/PS grafted CNFs	478:497	PMMA/PS grafted CNFs	478:497	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	16	theme	surface-initiated	385:401	arg1	RDRP					467:470	RDRP	467:470	RDRP	467:470	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	16	theme	surface-initiated	385:401	arg1	polymerizations					450:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations	385:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP)	385:471	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	4	17	theme	nanocomposites	757:770	arg1	temperature					728:738	glass transition temperature	711:738	glass transition temperature	711:738	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	4	17	theme	nanocomposites	757:770	arg1	transparency					674:685	Optical transparency	666:685	Optical transparency	666:685	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	4	17	theme	nanocomposites	757:770	arg1	stability					696:704	thermal stability	688:704	thermal stability	688:704	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	5	18	theme	fracture	859:866	arg1	surface					868:874	The uniform fracture surface	847:874	The uniform fracture surface	847:874	The uniform fracture surface confirmed the uniform dispersity by morphological observation.					
36347373	6	19	theme	tensile	1031:1037	arg1	modulus					1039:1045	tensile modulus	1031:1045	tensile modulus	1031:1045	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	4	20	theme	one-component	743:755	arg1	nanocomposites					757:770	one-component nanocomposites	743:770	one-component nanocomposites	743:770	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	6	21	theme	grafted	1116:1122	arg1	composite					1142:1150	grafted CNF one-component composite	1116:1150	grafted CNF one-component composite	1116:1150	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	1	22	theme	polystyrene	180:190	arg1	CNF					226:228	CNF	226:228	CNF	226:228	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	1	22	theme	polystyrene	180:190	arg1	nanofiber					215:223	polystyrene (PS) grafted cellulose nanofiber	180:223	polystyrene (PS) grafted cellulose nanofiber (CNF)	180:229	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	2	23	theme	-mediated	408:416	arg1	RDRP					467:470	RDRP	467:470	RDRP	467:470	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	23	theme	-mediated	408:416	arg1	polymerizations					450:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations	385:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP)	385:471	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	7	24	dep	achieve	1292:1298	arg1	moderated					1300:1308	moderated	1300:1308	to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability	1289:1405	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	2	25	dep	-mediated	408:416	arg1	reversible					418:427	reversible	418:427	reversible	418:427	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	1	26	theme	One-component	106:118	arg1	nanocomposites					120:133	One-component nanocomposites	106:133	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage	106:264	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	7	27	theme	obtaining	1200:1208	arg1	nanocomposites					1224:1237	obtaining one-component nanocomposites	1200:1237	obtaining one-component nanocomposites with high enough graft chain length	1200:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	7	28	theme	manufacturing	1385:1397	arg1	ability					1399:1405	thermal manufacturing ability	1377:1405	thermal manufacturing ability	1377:1405	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	0	29	theme	Thermoformable	0:13	arg1	nanocomposites					45:58	Thermoformable and transparent one-component nanocomposites	0:58	Thermoformable and transparent one-component nanocomposites based on surface	0:75	Thermoformable and transparent one-component nanocomposites based on surface grafted cellulose nanofiber.					
36347373	7	30	theme	optical	1354:1360	arg1	properties					1362:1371	optical properties	1354:1371	optical properties	1354:1371	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	1	31	theme	PS	193:194	arg1	CNF					226:228	CNF	226:228	CNF	226:228	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	1	31	theme	PS	193:194	arg1	nanofiber					215:223	polystyrene (PS) grafted cellulose nanofiber	180:223	polystyrene (PS) grafted cellulose nanofiber (CNF)	180:229	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	0	32	theme	one-component	31:43	arg1	nanocomposites					45:58	Thermoformable and transparent one-component nanocomposites	0:58	Thermoformable and transparent one-component nanocomposites based on surface	0:75	Thermoformable and transparent one-component nanocomposites based on surface grafted cellulose nanofiber.					
36347373	2	33	theme	graft	513:517	arg1	percentage					519:528	a graft percentage	511:528	a graft percentage	511:528	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	34	theme	ambient	295:301	arg1	conditions					303:312	relative ambient conditions	286:312	relative ambient conditions	286:312	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	1	35	with	nanocomposites	120:133	arg1	percentage					255:264	high polymer graft percentage	236:264	high polymer graft percentage	236:264	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	6	36	theme	tensile	992:998	arg1	strength					1000:1007	tensile strength	992:1007	tensile strength	992:1007	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	3	37	theme	composite	592:600	arg1	films					602:606	The one-component composite films	574:606	The one-component composite films	574:606	The one-component composite films were manufactured by simple hot-pressing subsequentially.					
36347373	2	38	theme	relative	286:293	arg1	conditions					303:312	relative ambient conditions	286:312	relative ambient conditions	286:312	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	1	39	theme	grafted	197:203	arg1	CNF					226:228	CNF	226:228	CNF	226:228	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	1	39	theme	grafted	197:203	arg1	nanofiber					215:223	polystyrene (PS) grafted cellulose nanofiber	180:223	polystyrene (PS) grafted cellulose nanofiber (CNF)	180:229	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	7	40	theme	glassy	1179:1184	arg1	chains					1192:1197	glassy graft chains	1179:1197	glassy graft chains	1179:1197	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	6	41	theme	graft	1073:1077	arg1	percentage					1079:1088	the graft percentage	1069:1088	the graft percentage	1069:1088	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	7	42	with	nanocomposites	1224:1237	arg1	length					1268:1273	high enough graft chain length	1244:1273	high enough graft chain length	1244:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	1	43	theme	cellulose	205:213	arg1	CNF					226:228	CNF	226:228	CNF	226:228	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	1	43	theme	cellulose	205:213	arg1	nanofiber					215:223	polystyrene (PS) grafted cellulose nanofiber	180:223	polystyrene (PS) grafted cellulose nanofiber (CNF)	180:229	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	2	44	theme	radical	442:448	arg1	RDRP					467:470	RDRP	467:470	RDRP	467:470	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	44	theme	radical	442:448	arg1	polymerizations					450:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations	385:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP)	385:471	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	7	45	theme	graft	1186:1190	arg1	chains					1192:1197	glassy graft chains	1179:1197	glassy graft chains	1179:1197	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	5	46	theme	uniform	851:857	arg1	surface					868:874	The uniform fracture surface	847:874	The uniform fracture surface	847:874	The uniform fracture surface confirmed the uniform dispersity by morphological observation.					
36347373	2	47	theme	deactivation	429:440	arg1	RDRP					467:470	RDRP	467:470	RDRP	467:470	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	2	47	theme	deactivation	429:440	arg1	polymerizations					450:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations	385:464	surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP)	385:471	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	6	48	theme	break	971:975	arg1	elongation					977:986	break elongation	971:986	break elongation	971:986	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	3	49	theme	one-component	578:590	arg1	films					602:606	The one-component composite films	574:606	The one-component composite films	574:606	The one-component composite films were manufactured by simple hot-pressing subsequentially.					
36347373	4	50	theme	bicomponent	820:830	arg1	nanocomposite					832:844	the bicomponent nanocomposite	816:844	the bicomponent nanocomposite	816:844	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	2	51	theme	vinyl	327:331	arg1	monomer					333:339	less active vinyl monomer	315:339	less active vinyl monomer	315:339	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	3	52	theme	simple	629:634	arg1	subsequentially					649:663	simple hot-pressing subsequentially	629:663	simple hot-pressing subsequentially	629:663	The one-component composite films were manufactured by simple hot-pressing subsequentially.					
36347373	1	53	theme	methyl	149:154	arg1	poly					144:147	poly	144:147	poly(methyl methacrylate)(PMMA)	144:174	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	1	53	theme	methyl	149:154	arg1	methacrylate					156:167	methyl methacrylate	149:167	methyl methacrylate	149:167	One-component nanocomposites based on poly(methyl methacrylate)(PMMA) and polystyrene (PS) grafted cellulose nanofiber (CNF) with high polymer graft percentage were fabricated.					
36347373	4	54	theme	transition	717:726	arg1	temperature					728:738	glass transition temperature	711:738	glass transition temperature	711:738	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	4	55	theme	thermal	688:694	arg1	stability					696:704	thermal stability	688:704	thermal stability	688:704	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
36347373	2	56	theme	active	320:325	arg1	monomer					333:339	less active vinyl monomer	315:339	less active vinyl monomer	315:339	At relative ambient conditions, less active vinyl monomer, MMA, and styrene were grafted from CNF via surface-initiated Cu(0)-mediated reversible deactivation radical polymerizations (RDRP), and PMMA/PS grafted CNFs could reach a graft percentage as high as 7550 % and 3530 %, respectively.					
36347373	0	57	theme	cellulose	85:93	arg1	nanofiber					95:103	cellulose nanofiber	85:103	cellulose nanofiber	85:103	Thermoformable and transparent one-component nanocomposites based on surface grafted cellulose nanofiber.					
36347373	5	58	theme	uniform	890:896	arg1	dispersity					898:907	the uniform dispersity	886:907	the uniform dispersity	886:907	The uniform fracture surface confirmed the uniform dispersity by morphological observation.					
36347373	0	59	theme	transparent	19:29	arg1	nanocomposites					45:58	Thermoformable and transparent one-component nanocomposites	0:58	Thermoformable and transparent one-component nanocomposites based on surface	0:75	Thermoformable and transparent one-component nanocomposites based on surface grafted cellulose nanofiber.					
36347373	7	60	theme	mechanical	1310:1319	arg1	performance					1321:1331	mechanical performance	1310:1331	mechanical performance	1310:1331	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	6	61	theme	one-component	1128:1140	arg1	composite					1142:1150	grafted CNF one-component composite	1116:1150	grafted CNF one-component composite	1116:1150	Mechanical tests indicated that break elongation and tensile strength ascended notably, and tensile modulus slightly descended as the graft percentage increased for PS and PMMA grafted CNF one-component composite.					
36347373	7	62	theme	one-component	1210:1222	arg1	nanocomposites					1224:1237	obtaining one-component nanocomposites	1200:1237	obtaining one-component nanocomposites with high enough graft chain length	1200:1273	It was concluded that for glassy graft chains, obtaining one-component nanocomposites with high enough graft chain length was essential to achieve moderated mechanical performance without compromising optical properties and thermal manufacturing ability.					
36347373	4	63	with	contrast	802:809	arg1	nanocomposite					832:844	the bicomponent nanocomposite	816:844	the bicomponent nanocomposite	816:844	Optical transparency, thermal stability, and glass transition temperature of one-component nanocomposites were enhanced dramatically in contrast with the bicomponent nanocomposite.					
35364490	8	0	contain	has	1481:1483	arg1	CPP-3					1475:1479	CPP-3	1475:1479	CPP-3	1475:1479	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	8	0	contain	has	1481:1483	arg1	Meanwhile					1464:1472	Meanwhile	1464:1472	Meanwhile	1464:1472	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	8	0	contain	has	1481:1483	arg2	potential					1503:1511	great application potential	1485:1511	great application potential	1485:1511	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	4	1	theme	acetic	604:609	arg1	acid					611:614	acetic acid	604:614	acetic acid	604:614	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	6	2	theme	peel	1295:1298	arg1	activity					1320:1327	citrus peel pectins antioxidant activity	1288:1327	citrus peel pectins antioxidant activity	1288:1327	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	2	3	theme	monosaccharide	369:382	arg1	composition					384:394	monosaccharide composition	369:394	monosaccharide composition	369:394	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	6	4	theme	pectins	1184:1190	arg1	viscosity					1159:1167	viscosity	1159:1167	viscosity	1159:1167	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	4	theme	pectins	1184:1190	arg1	stability					1145:1153	thermal stability	1137:1153	thermal stability	1137:1153	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	5	theme	citrus	1172:1177	arg1	pectins					1184:1190	citrus peel pectins	1172:1190	citrus peel pectins	1172:1190	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	8	6	from	stabilizer	1578:1587	arg1	industry					1601:1608	the food industry	1592:1608	the food industry	1592:1608	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	1	7	theme	physicochemical	189:203	arg1	properties					205:214	physicochemical properties	189:214	physicochemical properties	189:214	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	5	8	dep	Shatangju	788:796	arg1	activity					863:870	own superior antioxidant biological activity	827:870	own superior antioxidant biological activity	827:870	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	7	9	theme	natural	1401:1407	arg1	antioxidant					1409:1419	a potential natural antioxidant	1389:1419	a potential natural antioxidant in pharmaceutical and cosmetic industries	1389:1461	Our findings suggest that CPP-6 and CPP-7 may be useful as a potential natural antioxidant in pharmaceutical and cosmetic industries.					
35364490	4	10	theme	molecular	669:677	arg1	distributions					686:698	broad molecular weight distributions	663:698	broad molecular weight distributions	663:698	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	3	11	theme	citrus	543:548	arg1	CPPs					564:567	CPPs	564:567	CPPs	564:567	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	3	11	theme	citrus	543:548	arg1	pectins					555:561	citrus peel pectins	543:561	citrus peel pectins (CPPs)	543:568	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	5	12	theme	antioxidant	840:850	arg1	activity					863:870	own superior antioxidant biological activity	827:870	own superior antioxidant biological activity	827:870	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	4	13	with	polysaccharides	642:656	arg1	distributions					686:698	broad molecular weight distributions	663:698	broad molecular weight distributions	663:698	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	3	14	contain	have	497:500	arg1	cultivars					469:477	the different cultivars	455:477	the different cultivars	455:477	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	3	14	contain	have	497:500	arg2	effects					514:520	significant effects	502:520	significant effects	502:520	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	3	14	contain	have	497:500	arg1	areas					491:495	growing areas	483:495	growing areas	483:495	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	6	15	theme	I	1240:1240	arg1	region					1242:1247	rhamnogalacturonan I region	1221:1247	rhamnogalacturonan I region	1221:1247	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	5	16	contain	had	915:917	arg1	Xuecheng					810:817	Xuecheng	810:817	Xuecheng	810:817	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg2	properties					940:949	excellent functional properties	919:949	excellent functional properties	919:949	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	Shatangju					788:796	Shatangju	788:796	Shatangju	788:796	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	Buzhihuo					898:905	Buzhihuo	898:905	Buzhihuo	898:905	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	CPP-7					820:824	CPP-7	820:824	CPP-7	820:824	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	Dahongpao					876:884	Dahongpao	876:884	Dahongpao	876:884	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	CPP-6					799:803	CPP-6	799:803	CPP-6	799:803	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	CPP-9					908:912	CPP-9	908:912	CPP-9	908:912	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	16	contain	had	915:917	arg1	CPP-3					887:891	CPP-3	887:891	CPP-3	887:891	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	8	17	from	thickener	1565:1573	arg1	industry					1601:1608	the food industry	1592:1608	the food industry	1592:1608	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	8	18	theme	great	1485:1489	arg1	potential					1503:1511	great application potential	1485:1511	great application potential	1485:1511	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	6	19	theme	antioxidant	1308:1318	arg1	activity					1320:1327	citrus peel pectins antioxidant activity	1288:1327	citrus peel pectins antioxidant activity	1288:1327	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	5	20	theme	excellent	919:927	arg1	properties					940:949	excellent functional properties	919:949	excellent functional properties	919:949	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	6	21	theme	rhamnose	1203:1210	arg1	content					1212:1218	the rhamnose content	1199:1218	the rhamnose content	1199:1218	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	2	22	dep	Fourier	302:308	arg1	transform					310:318	transform	310:318	transform infrared	310:327	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	0	23	theme	citrus	69:74	arg1	pectins					81:87	different citrus peel pectins	59:87	different citrus peel pectins	59:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	5	24	theme	own	827:829	arg1	activity					863:870	own superior antioxidant biological activity	827:870	own superior antioxidant biological activity	827:870	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	1	25	theme	growth	151:156	arg1	regions					158:164	growth regions	151:164	growth regions	151:164	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	6	26	theme	correlation	1003:1013	arg1	analysis					1015:1022	the correlation analysis	999:1022	the correlation analysis	999:1022	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	8	27	theme	high	1516:1519	arg1	temperature					1521:1531	high temperature	1516:1531	high temperature food	1516:1536	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	4	28	theme	domain	737:742	arg1	proportions					713:723	high proportions	708:723	high proportions of the RG-I domain	708:742	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	0	29	theme	pectins	81:87	arg1	activity					47:54	antioxidant activity	35:54	antioxidant activity of different citrus peel pectins	35:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	0	29	theme	pectins	81:87	arg1	Comparison					0:9	Comparison	0:9	Comparison of characterization	0:29	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	5	30	dep	had	915:917	arg1	viscosity					974:982	viscosity	974:982	viscosity	974:982	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	5	30	dep	had	915:917	arg1	stability					960:968	thermal stability	952:968	thermal stability	952:968	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	1	31	theme	citrus	112:117	arg1	peel					119:122	citrus peel	112:122	citrus peel of different cultivars and growth regions	112:164	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	1	32	theme	cultivars	137:145	arg1	peel					119:122	citrus peel	112:122	citrus peel of different cultivars and growth regions	112:164	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	5	33	theme	peel	774:777	arg1	pectins					779:785	citrus peel pectins	767:785	citrus peel pectins	767:785	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	0	34	theme	peel	76:79	arg1	pectins					81:87	different citrus peel pectins	59:87	different citrus peel pectins	59:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	4	35	theme	Citrus	571:576	arg1	pectins					583:589	Citrus peel pectins	571:589	Citrus peel pectins extracted by acetic acid	571:614	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	0	36	theme	characterization	14:29	arg1	activity					47:54	antioxidant activity	35:54	antioxidant activity of different citrus peel pectins	35:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	0	36	theme	characterization	14:29	arg1	Comparison					0:9	Comparison	0:9	Comparison of characterization	0:29	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	5	37	theme	thermal	952:958	arg1	stability					960:968	thermal stability	952:968	thermal stability	952:968	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	6	38	theme	galacturonic	1043:1054	arg1	content					1061:1067	galacturonic acid content	1043:1067	galacturonic acid content	1043:1067	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	3	39	theme	growing	483:489	arg1	areas					491:495	growing areas	483:495	growing areas	483:495	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	0	40	theme	antioxidant	35:45	arg1	activity					47:54	antioxidant activity	35:54	antioxidant activity of different citrus peel pectins	35:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	6	41	theme	thermal	1137:1143	arg1	stability					1145:1153	thermal stability	1137:1153	thermal stability	1137:1153	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	2	42	theme	physicochemical	255:269	arg1	features					271:278	The physicochemical features	251:278	The physicochemical features	251:278	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	2	43	theme	weight	348:353	arg1	distribution					355:366	molecular weight distribution	338:366	molecular weight distribution	338:366	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	6	44	theme	peel	1179:1182	arg1	pectins					1184:1190	citrus peel pectins	1172:1190	citrus peel pectins	1172:1190	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	4	45	contain	had	704:706	arg2	proportions					713:723	high proportions	708:723	high proportions of the RG-I domain	708:742	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	4	45	contain	had	704:706	arg1	pectins					583:589	Citrus peel pectins	571:589	Citrus peel pectins extracted by acetic acid	571:614	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	6	46	dep	stability	1145:1153	arg1	the					1133:1135	the	1133:1135	the	1133:1135	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	3	47	theme	peel	550:553	arg1	CPPs					564:567	CPPs	564:567	CPPs	564:567	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	3	47	theme	peel	550:553	arg1	pectins					555:561	citrus peel pectins	543:561	citrus peel pectins (CPPs)	543:568	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	6	48	theme	pectins	1300:1306	arg1	activity					1320:1327	citrus peel pectins antioxidant activity	1288:1327	citrus peel pectins antioxidant activity	1288:1327	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	49	theme	methyl-esterification	1083:1103	arg1	weight					1035:1040	molecular weight	1025:1040	molecular weight	1025:1040	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	49	theme	methyl-esterification	1083:1103	arg1	degree					1073:1078	degree	1073:1078	degree of methyl-esterification	1073:1103	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	49	theme	methyl-esterification	1083:1103	arg1	content					1061:1067	galacturonic acid content	1043:1067	galacturonic acid content	1043:1067	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	50	theme	citrus	1288:1293	arg1	activity					1320:1327	citrus peel pectins antioxidant activity	1288:1327	citrus peel pectins antioxidant activity	1288:1327	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	7	51	theme	cosmetic	1443:1450	arg1	industries					1452:1461	pharmaceutical and cosmetic industries	1424:1461	pharmaceutical and cosmetic industries	1424:1461	Our findings suggest that CPP-6 and CPP-7 may be useful as a potential natural antioxidant in pharmaceutical and cosmetic industries.					
35364490	6	52	theme	molecular	1259:1267	arg1	weight					1269:1274	lower molecular weight	1253:1274	lower molecular weight	1253:1274	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	6	53	theme	lower	1253:1257	arg1	weight					1269:1274	lower molecular weight	1253:1274	lower molecular weight	1253:1274	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	7	54	theme	pharmaceutical	1424:1437	arg1	industries					1452:1461	pharmaceutical and cosmetic industries	1424:1461	pharmaceutical and cosmetic industries	1424:1461	Our findings suggest that CPP-6 and CPP-7 may be useful as a potential natural antioxidant in pharmaceutical and cosmetic industries.					
35364490	4	55	theme	high	708:711	arg1	proportions					713:723	high proportions	708:723	high proportions of the RG-I domain	708:742	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	5	56	theme	superior	831:838	arg1	activity					863:870	own superior antioxidant biological activity	827:870	own superior antioxidant biological activity	827:870	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	2	57	theme	thermal	397:403	arg1	behaviors					405:413	thermal behaviors	397:413	thermal behaviors	397:413	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	2	58	dep	transform	310:318	arg1	infrared					320:327	infrared	320:327	transform infrared	310:327	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	4	59	theme	broad	663:667	arg1	distributions					686:698	broad molecular weight distributions	663:698	broad molecular weight distributions	663:698	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	5	60	theme	biological	852:861	arg1	activity					863:870	own superior antioxidant biological activity	827:870	own superior antioxidant biological activity	827:870	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	7	61	theme	potential	1391:1399	arg1	antioxidant					1409:1419	a potential natural antioxidant	1389:1419	a potential natural antioxidant in pharmaceutical and cosmetic industries	1389:1461	Our findings suggest that CPP-6 and CPP-7 may be useful as a potential natural antioxidant in pharmaceutical and cosmetic industries.					
35364490	4	62	theme	weight	679:684	arg1	distributions					686:698	broad molecular weight distributions	663:698	broad molecular weight distributions	663:698	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	8	63	theme	application	1491:1501	arg1	potential					1503:1511	great application potential	1485:1511	great application potential	1485:1511	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	6	64	theme	rhamnogalacturonan	1221:1238	arg1	region					1242:1247	rhamnogalacturonan I region	1221:1247	rhamnogalacturonan I region	1221:1247	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	8	65	dep	thickener	1565:1573	arg1	a					1563:1563	a	1563:1563	a	1563:1563	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	1	66	theme	different	127:135	arg1	cultivars					137:145	different cultivars	127:145	different cultivars	127:145	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	7	67	from	antioxidant	1409:1419	arg1	industries					1452:1461	pharmaceutical and cosmetic industries	1424:1461	pharmaceutical and cosmetic industries	1424:1461	Our findings suggest that CPP-6 and CPP-7 may be useful as a potential natural antioxidant in pharmaceutical and cosmetic industries.					
35364490	6	68	theme	molecular	1025:1033	arg1	weight					1035:1040	molecular weight	1025:1040	molecular weight	1025:1040	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	5	69	theme	pectins	779:785	arg1	kinds					758:762	the 10 kinds	751:762	the 10 kinds of citrus peel pectins	751:785	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	8	70	theme	temperature	1521:1531	arg1	food					1533:1536	high temperature food	1516:1536	high temperature food	1516:1536	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	1	71	theme	regions	158:164	arg1	peel					119:122	citrus peel	112:122	citrus peel of different cultivars and growth regions	112:164	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	4	72	theme	RG-I	732:735	arg1	domain					737:742	the RG-I domain	728:742	the RG-I domain	728:742	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	8	73	used	used	1555:1558	arg2	CPP-9					1542:1546	CPP-9	1542:1546	CPP-9	1542:1546	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	8	73	used	used	1555:1558	arg2	stabilizer					1578:1587	stabilizer	1578:1587	stabilizer	1578:1587	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	8	73	used	used	1555:1558	arg2	thickener					1565:1573	thickener	1565:1573	thickener	1565:1573	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	5	74	theme	citrus	767:772	arg1	pectins					779:785	citrus peel pectins	767:785	citrus peel pectins	767:785	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	2	75	theme	flow	419:422	arg1	behaviors					424:432	flow behaviors	419:432	flow behaviors	419:432	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	5	76	theme	functional	929:938	arg1	properties					940:949	excellent functional properties	919:949	excellent functional properties	919:949	Among the 10 kinds of citrus peel pectins, Shatangju (CPP-6) and Xuecheng (CPP-7) own superior antioxidant biological activity and Dahongpao (CPP-3) and Buzhihuo (CPP-9) had excellent functional properties (thermal stability and viscosity).					
35364490	4	77	theme	peel	578:581	arg1	pectins					583:589	Citrus peel pectins	571:589	Citrus peel pectins extracted by acetic acid	571:614	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	3	78	theme	different	459:467	arg1	cultivars					469:477	the different cultivars	455:477	the different cultivars	455:477	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	6	79	theme	acid	1056:1059	arg1	content					1061:1067	galacturonic acid content	1043:1067	galacturonic acid content	1043:1067	According to the correlation analysis, molecular weight, galacturonic acid content and degree of methyl-esterification were beneficial to increase the thermal stability and viscosity of citrus peel pectins, while the rhamnose content, rhamnogalacturonan I region and lower molecular weight can improve citrus peel pectins antioxidant activity.					
35364490	3	80	theme	significant	502:512	arg1	effects					514:520	significant effects	502:520	significant effects	502:520	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
35364490	1	81	theme	antioxidant	220:230	arg1	activity					232:239	antioxidant activity	220:239	antioxidant activity in vitro	220:248	Pectins obtained from citrus peel of different cultivars and growth regions were compared based on physicochemical properties and antioxidant activity in vitro.					
35364490	0	82	theme	different	59:67	arg1	pectins					81:87	different citrus peel pectins	59:87	different citrus peel pectins	59:87	Comparison of characterization and antioxidant activity of different citrus peel pectins.					
35364490	8	83	theme	food	1596:1599	arg1	industry					1601:1608	the food industry	1592:1608	the food industry	1592:1608	Meanwhile, CPP-3 has great application potential in high temperature food and CPP-9 can be used as a thickener or stabilizer in the food industry.					
35364490	4	84	theme	heterogeneous	628:640	arg1	polysaccharides					642:656	highly heterogeneous polysaccharides	621:656	highly heterogeneous polysaccharides with broad molecular weight distributions	621:698	Citrus peel pectins extracted by acetic acid were highly heterogeneous polysaccharides with broad molecular weight distributions and had high proportions of the RG-I domain.					
35364490	2	85	theme	molecular	338:346	arg1	distribution					355:366	molecular weight distribution	338:366	molecular weight distribution	338:366	The physicochemical features were elucidated using Fourier transform infrared (FT-IR), molecular weight distribution, monosaccharide composition, thermal behaviors and flow behaviors.					
35364490	3	86	theme	pectins	555:561	arg1	properties					529:538	the properties	525:538	the properties of citrus peel pectins (CPPs)	525:568	Results showed that the different cultivars and growing areas have significant effects on the properties of citrus peel pectins (CPPs).					
36574135	7	0	theme	coated	1112:1117	arg1	samples					1138:1144	both coated and functionalized samples	1107:1144	both coated and functionalized samples	1107:1144	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	6	1	theme	Porous	817:822	arg1	carrier					932:938	a potential carrier	920:938	a potential carrier for the controlled drug release of sulfasalazine	920:987	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	6	1	theme	Porous	817:822	arg1	PSi					832:834	PSi	832:834	PSi	832:834	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	6	1	theme	Porous	817:822	arg1	silica					824:829	Porous silica	817:829	Porous silica (PSi)	817:835	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	7	2	theme	gastric	1027:1033	arg1	media					1050:1054	simulated gastric and intestinal media	1017:1054	simulated gastric and intestinal media	1017:1054	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	5	3	theme	porous	796:801	arg1	disks					810:814	pressed porous silica disks	788:814	pressed porous silica disks	788:814	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	8	4	theme	suitable	1350:1357	arg1	rate					1359:1362	a suitable rate	1348:1362	a suitable rate	1348:1362	It is concluded that the coat with a 50:50 ratio can release the colon drugs in 24 h at a suitable rate.					
36574135	9	5	theme	functionalized	1488:1501	arg1	samples					1503:1509	the functionalized samples	1484:1509	the functionalized samples	1484:1509	It is also envisioned that functionalization was a factor boosting drug uptake, however, the release rate was lower in the functionalized samples.					
36574135	3	6	from	rate	475:478	arg1	media					506:510	a simulated intestinal media	483:510	a simulated intestinal media	483:510	In this study, porous silica was synthesized and sulfasalazine was loaded into it to investigate the release rate in a simulated intestinal media.					
36574135	5	7	theme	silica	803:808	arg1	disks					810:814	pressed porous silica disks	788:814	pressed porous silica disks	788:814	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	8	theme	O-Carboxymethyl	659:673	arg1	NOCC					685:688	NOCC	685:688	NOCC	685:688	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	8	theme	O-Carboxymethyl	659:673	arg1	N					656:656	N	656:656	N	656:656	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	8	theme	O-Carboxymethyl	659:673	arg1	chitosan					675:682	O-Carboxymethyl chitosan	659:682	O-Carboxymethyl chitosan (NOCC)	659:689	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	9	theme	pressed	788:794	arg1	disks					810:814	pressed porous silica disks	788:814	pressed porous silica disks	788:814	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	10	10	theme	sulfasalazine	1601:1613	arg1	delivery					1589:1596	the potential safe and localized delivery	1556:1596	the potential safe and localized delivery of sulfasalazine	1556:1613	This study opens the gates to new ideas for the potential safe and localized delivery of sulfasalazine.					
36574135	10	11	theme	new	1542:1544	arg1	ideas					1546:1550	new ideas	1542:1550	new ideas for the potential safe and localized delivery of sulfasalazine	1542:1613	This study opens the gates to new ideas for the potential safe and localized delivery of sulfasalazine.					
36574135	7	12	theme	simulated	1017:1025	arg1	media					1050:1054	simulated gastric and intestinal media	1017:1054	simulated gastric and intestinal media	1017:1054	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	7	13	theme	coats	1173:1177	arg1	degree					1163:1168	the swelling degree	1150:1168	the swelling degree of coats at basic and neutral media	1150:1204	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	7	14	theme	swelling	1154:1161	arg1	degree					1163:1168	the swelling degree	1150:1168	the swelling degree of coats at basic and neutral media	1150:1204	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	5	15	theme	different	742:750	arg1	ratios					752:757	different ratios	742:757	different ratios	742:757	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	3	16	theme	intestinal	495:504	arg1	media					506:510	a simulated intestinal media	483:510	a simulated intestinal media	483:510	In this study, porous silica was synthesized and sulfasalazine was loaded into it to investigate the release rate in a simulated intestinal media.					
36574135	6	17	theme	controlled	948:957	arg1	release					964:970	the controlled drug release	944:970	the controlled drug release of sulfasalazine	944:987	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	0	18	theme	Alginate-N	86:95	arg1	Coating					127:133	O-Carboxymethyl Chitosan Gel Coating	98:133	O-Carboxymethyl Chitosan Gel Coating	98:133	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	18	theme	Alginate-N	86:95	arg1	Functionalization					145:161	Amine Functionalization	139:161	Amine Functionalization	139:161	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	18	theme	Alginate-N	86:95	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	2	19	from	useful	340:345	arg1	delivery					356:363	colon delivery	350:363	colon delivery	350:363	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	5	20	theme	%	732:732	arg1	composition					718:728	a distinct composition	707:728	a distinct composition (3% W/V) in different ratios	707:757	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	20	theme	%	732:732	arg1	W/V					734:736	3% W/V	731:736	3% W/V	731:736	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	6	21	theme	sulfasalazine	975:987	arg1	release					964:970	the controlled drug release	944:970	the controlled drug release of sulfasalazine	944:987	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	10	22	theme	localized	1579:1587	arg1	delivery					1589:1596	the potential safe and localized delivery	1556:1596	the potential safe and localized delivery of sulfasalazine	1556:1613	This study opens the gates to new ideas for the potential safe and localized delivery of sulfasalazine.					
36574135	7	23	theme	functionalized	1123:1136	arg1	samples					1138:1144	both coated and functionalized samples	1107:1144	both coated and functionalized samples	1107:1144	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	4	24	theme	body	618:621	arg1	flow					629:632	body fluid flow	618:632	body fluid flow	618:632	The media was kept at 37 °C and pH 6.8 and 7.4, and subjected to continuous ultrasonic waves to simulate body fluid flow.					
36574135	0	25	theme	Porous	0:5	arg1	Silica					7:12	Porous Silica	0:12	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.	0:162	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	6	26	theme	aminopropyltrimethoxysilane	864:890	arg1	grafting					892:899	aminopropyltrimethoxysilane grafting	864:899	aminopropyltrimethoxysilane grafting	864:899	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	2	27	theme	biocompatible	292:304	arg1	polymer					325:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	1	28	theme	colon-specific	181:194	arg1	systems					210:216	colon-specific drug delivery systems	181:216	colon-specific drug delivery systems	181:216	The necessity of colon-specific drug delivery systems has been well recognized.					
36574135	0	29	theme	Drug	17:20	arg1	Carrier					22:28	Drug Carrier	17:28	Drug Carrier for Controlled Delivery of Sulfasalazine	17:69	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	7	30	theme	alginate	1235:1242	arg1	presence					1223:1230	the presence	1219:1230	the presence of alginate	1219:1242	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	0	31	theme	Chitosan	114:121	arg1	Coating					127:133	O-Carboxymethyl Chitosan Gel Coating	98:133	O-Carboxymethyl Chitosan Gel Coating	98:133	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	31	theme	Chitosan	114:121	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	1	32	theme	drug	196:199	arg1	systems					210:216	colon-specific drug delivery systems	181:216	colon-specific drug delivery systems	181:216	The necessity of colon-specific drug delivery systems has been well recognized.					
36574135	9	33	theme	drug	1432:1435	arg1	uptake					1437:1442	drug uptake	1432:1442	drug uptake	1432:1442	It is also envisioned that functionalization was a factor boosting drug uptake, however, the release rate was lower in the functionalized samples.					
36574135	0	34	theme	O-Carboxymethyl	98:112	arg1	Coating					127:133	O-Carboxymethyl Chitosan Gel Coating	98:133	O-Carboxymethyl Chitosan Gel Coating	98:133	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	34	theme	O-Carboxymethyl	98:112	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	2	35	theme	pH-sensitive	278:289	arg1	polymer					325:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	8	36	with	coat	1285:1288	arg1	ratio					1303:1307	a 50:50 ratio	1295:1307	a 50:50 ratio	1295:1307	It is concluded that the coat with a 50:50 ratio can release the colon drugs in 24 h at a suitable rate.					
36574135	1	37	theme	delivery	201:208	arg1	systems					210:216	colon-specific drug delivery systems	181:216	colon-specific drug delivery systems	181:216	The necessity of colon-specific drug delivery systems has been well recognized.					
36574135	3	38	theme	porous	381:386	arg1	silica					388:393	porous silica	381:393	porous silica	381:393	In this study, porous silica was synthesized and sulfasalazine was loaded into it to investigate the release rate in a simulated intestinal media.					
36574135	7	39	theme	basic	1182:1186	arg1	media					1200:1204	basic and neutral media	1182:1204	basic and neutral media	1182:1204	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	5	40	theme	N	656:656	arg1	solutions					691:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions	635:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions	635:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	4	41	theme	ultrasonic	589:598	arg1	waves					600:604	continuous ultrasonic waves	578:604	continuous ultrasonic waves	578:604	The media was kept at 37 °C and pH 6.8 and 7.4, and subjected to continuous ultrasonic waves to simulate body fluid flow.					
36574135	1	42	theme	systems	210:216	arg1	necessity					168:176	The necessity	164:176	The necessity of colon-specific drug delivery systems	164:216	The necessity of colon-specific drug delivery systems has been well recognized.					
36574135	5	43	theme	distinct	709:716	arg1	composition					718:728	a distinct composition	707:728	a distinct composition (3% W/V) in different ratios	707:757	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	43	theme	distinct	709:716	arg1	W/V					734:736	3% W/V	731:736	3% W/V	731:736	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	0	44	theme	Gel	123:125	arg1	Coating					127:133	O-Carboxymethyl Chitosan Gel Coating	98:133	O-Carboxymethyl Chitosan Gel Coating	98:133	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	44	theme	Gel	123:125	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	4	45	theme	continuous	578:587	arg1	waves					600:604	continuous ultrasonic waves	578:604	continuous ultrasonic waves	578:604	The media was kept at 37 °C and pH 6.8 and 7.4, and subjected to continuous ultrasonic waves to simulate body fluid flow.					
36574135	7	46	theme	intestinal	1039:1048	arg1	media					1050:1054	simulated gastric and intestinal media	1017:1054	simulated gastric and intestinal media	1017:1054	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	10	47	theme	potential	1560:1568	arg1	delivery					1589:1596	the potential safe and localized delivery	1556:1596	the potential safe and localized delivery of sulfasalazine	1556:1613	This study opens the gates to new ideas for the potential safe and localized delivery of sulfasalazine.					
36574135	0	48	theme	Amine	139:143	arg1	Functionalization					145:161	Amine Functionalization	139:161	Amine Functionalization	139:161	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	48	theme	Amine	139:143	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	8	49	theme	colon	1325:1329	arg1	drugs					1331:1335	the colon drugs	1321:1335	the colon drugs	1321:1335	It is concluded that the coat with a 50:50 ratio can release the colon drugs in 24 h at a suitable rate.					
36574135	2	50	from	delivery	356:363	arg1	useful					340:345	useful	340:345	useful	340:345	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	0	51	theme	Controlled	34:43	arg1	Delivery					45:52	Controlled Delivery	34:52	Controlled Delivery of Sulfasalazine	34:69	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	5	52	theme	alginate	643:650	arg1	solutions					691:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions	635:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions	635:699	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	9	53	theme	release	1458:1464	arg1	lower					1475:1479	lower	1475:1479	lower	1475:1479	It is also envisioned that functionalization was a factor boosting drug uptake, however, the release rate was lower in the functionalized samples.					
36574135	9	53	theme	release	1458:1464	arg1	rate					1466:1469	the release rate	1454:1469	the release rate	1454:1469	It is also envisioned that functionalization was a factor boosting drug uptake, however, the release rate was lower in the functionalized samples.					
36574135	7	54	from	media	1200:1204	arg1	degree					1163:1168	the swelling degree	1150:1168	the swelling degree of coats at basic and neutral media	1150:1204	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	3	55	theme	release	467:473	arg1	rate					475:478	the release rate	463:478	the release rate in a simulated intestinal media	463:510	In this study, porous silica was synthesized and sulfasalazine was loaded into it to investigate the release rate in a simulated intestinal media.					
36574135	5	56	with	solutions	691:699	arg1	composition					718:728	a distinct composition	707:728	a distinct composition (3% W/V) in different ratios	707:757	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	5	56	with	solutions	691:699	arg1	W/V					734:736	3% W/V	731:736	3% W/V	731:736	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	8	57	theme	50:50	1297:1301	arg1	ratio					1303:1307	a 50:50 ratio	1295:1307	a 50:50 ratio	1295:1307	It is concluded that the coat with a 50:50 ratio can release the colon drugs in 24 h at a suitable rate.					
36574135	2	58	theme	biodegradable	311:323	arg1	polymer					325:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	a pH-sensitive, biocompatible, and biodegradable polymer	276:331	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	10	59	theme	safe	1570:1573	arg1	delivery					1589:1596	the potential safe and localized delivery	1556:1596	the potential safe and localized delivery of sulfasalazine	1556:1613	This study opens the gates to new ideas for the potential safe and localized delivery of sulfasalazine.					
36574135	5	60	theme	Aqueous	635:641	arg1	alginate					643:650	Aqueous alginate	635:650	Aqueous alginate	635:650	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	4	61	theme	fluid	623:627	arg1	flow					629:632	body fluid flow	618:632	body fluid flow	618:632	The media was kept at 37 °C and pH 6.8 and 7.4, and subjected to continuous ultrasonic waves to simulate body fluid flow.					
36574135	6	62	theme	potential	922:930	arg1	silica					824:829	Porous silica	817:829	Porous silica (PSi)	817:835	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	6	62	theme	potential	922:930	arg1	carrier					932:938	a potential carrier	920:938	a potential carrier for the controlled drug release of sulfasalazine	920:987	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	0	63	theme	Sulfasalazine	57:69	arg1	Delivery					45:52	Controlled Delivery	34:52	Controlled Delivery of Sulfasalazine	34:69	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	7	64	theme	neutral	1192:1198	arg1	media					1200:1204	basic and neutral media	1182:1204	basic and neutral media	1182:1204	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36574135	0	65	dep	Silica	7:12	arg1	Coating					127:133	O-Carboxymethyl Chitosan Gel Coating	98:133	O-Carboxymethyl Chitosan Gel Coating	98:133	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	65	dep	Silica	7:12	arg1	Functionalization					145:161	Amine Functionalization	139:161	Amine Functionalization	139:161	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	0	65	dep	Silica	7:12	arg1	Effect					76:81	The Effect	72:81	The Effect of Alginate-N	72:95	Porous Silica as Drug Carrier for Controlled Delivery of Sulfasalazine: The Effect of Alginate-N, O-Carboxymethyl Chitosan Gel Coating and Amine Functionalization.					
36574135	6	66	theme	drug	959:962	arg1	release					964:970	the controlled drug release	944:970	the controlled drug release of sulfasalazine	944:987	Porous silica (PSi) was also functionalized by aminopropyltrimethoxysilane grafting and was studied as a potential carrier for the controlled drug release of sulfasalazine.					
36574135	2	67	theme	colon	350:354	arg1	delivery					356:363	colon delivery	350:363	colon delivery	350:363	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	5	68	from	composition	718:728	arg1	ratios					752:757	different ratios	742:757	different ratios	742:757	Aqueous alginate and N, O-Carboxymethyl chitosan (NOCC) solutions, with a distinct composition (3% W/V) in different ratios, were prepared and coated on pressed porous silica disks.					
36574135	2	69	theme	Porous	244:249	arg1	silica					251:256	Porous silica	244:256	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer	244:331	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	2	69	theme	Porous	244:249	arg1	PSi					259:261	PSi	259:261	PSi	259:261	Porous silica (PSi) coated with a pH-sensitive, biocompatible, and biodegradable polymer can be useful in colon delivery.					
36574135	3	70	theme	simulated	485:493	arg1	media					506:510	a simulated intestinal media	483:510	a simulated intestinal media	483:510	In this study, porous silica was synthesized and sulfasalazine was loaded into it to investigate the release rate in a simulated intestinal media.					
36574135	7	71	theme	burst	1081:1085	arg1	release					1087:1093	no burst release	1078:1093	no burst release	1078:1093	The release was studied in simulated gastric and intestinal media and results show that no burst release occurred in both coated and functionalized samples and the swelling degree of coats at basic and neutral media decreased by the presence of alginate in the network.					
36179392	0	0	theme	novel	102:106	arg1	mediator					113:120	novel PdCu mediator	102:120	novel PdCu mediator	102:120	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	8	1	theme	fabricated	1222:1231	arg1	sensor					1241:1246	the fabricated lactate sensor	1218:1246	the fabricated lactate sensor	1218:1246	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	5	2	theme	active	837:842	arg1	area					852:855	the calculated active surface area	822:855	the calculated active surface area of the fabricated PdCu/LIG electrode	822:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	5	2	theme	active	837:842	arg1	∼12.8 mm2					898:906	∼12.8 mm2	898:906	∼12.8 mm2	898:906	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	1	3	theme	lactate	163:169	arg1	sensor					171:176	A lactate sensor	161:176	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst	161:288	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	6	4	theme	lactate	1039:1045	arg1	sensors					1047:1053	the fabricated lactate sensors	1024:1053	the fabricated lactate sensors with the LOx/PdCu/LIG electrode	1024:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	8	5	theme	ascorbic	1318:1325	arg1	acid					1327:1330	ascorbic acid	1318:1330	ascorbic acid	1318:1330	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	1	6	theme	electrodeposited	259:274	arg1	catalyst					281:288	an electrodeposited PdCu catalyst	256:288	an electrodeposited PdCu catalyst	256:288	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	7	7	theme	detection	1176:1184	arg1	limit					1167:1171	The calculated limit	1152:1171	The calculated limit of detection	1152:1184	The calculated limit of detection was 0.28 μM.					
36179392	4	8	theme	LOx/PdCu/LIG	756:767	arg1	structure					769:777	a LOx/PdCu/LIG structure	754:777	a LOx/PdCu/LIG structure	754:777	PdCu was electrodeposited on the LIG electrode and lactate oxidase (LOx) was immobilized on the LIG surface to create a LOx/PdCu/LIG structure.					
36179392	1	9	theme	PdCu	276:279	arg1	catalyst					281:288	an electrodeposited PdCu catalyst	256:288	an electrodeposited PdCu catalyst	256:288	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	0	10	theme	PdCu	108:111	arg1	mediator					113:120	novel PdCu mediator	102:120	novel PdCu mediator	102:120	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	3	11	theme	fabricated	559:568	arg1	electrode					574:582	the fabricated LIG electrode	555:582	the fabricated LIG electrode	555:582	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	2	12	theme	polyimide	353:361	arg1	surface					368:374	the polyimide film surface	349:374	the polyimide film surface	349:374	CO2 laser was used to convert the polyimide film surface to multilayered LIG.					
36179392	5	13	theme	surface	844:850	arg1	area					852:855	the calculated active surface area	822:855	the calculated active surface area of the fabricated PdCu/LIG electrode	822:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	5	13	theme	surface	844:850	arg1	∼12.8 mm2					898:906	∼12.8 mm2	898:906	∼12.8 mm2	898:906	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	3	14	theme	electron	481:488	arg1	microscopy					490:499	field-emission scanning electron microscopy	457:499	field-emission scanning electron microscopy	457:499	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	4	15	theme	lactate	687:693	arg1	LOx					704:706	LOx	704:706	LOx	704:706	PdCu was electrodeposited on the LIG electrode and lactate oxidase (LOx) was immobilized on the LIG surface to create a LOx/PdCu/LIG structure.					
36179392	4	15	theme	lactate	687:693	arg1	oxidase					695:701	lactate oxidase	687:701	lactate oxidase (LOx)	687:707	PdCu was electrodeposited on the LIG electrode and lactate oxidase (LOx) was immobilized on the LIG surface to create a LOx/PdCu/LIG structure.					
36179392	6	16	theme	LOx/PdCu/LIG	1064:1075	arg1	electrode					1077:1085	the LOx/PdCu/LIG electrode	1060:1085	the LOx/PdCu/LIG electrode	1060:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	5	17	theme	Randles-Ševčík	797:810	arg1	equation					812:819	the Randles-Ševčík equation	793:819	the Randles-Ševčík equation	793:819	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	3	18	dep	morphology	401:410	arg1	The					397:399	The	397:399	The	397:399	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	1	19	theme	lactate	182:188	arg1	sensing					190:196	lactate sensing	182:196	lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst	182:288	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	0	20	theme	performance	2:12	arg1	improvement					14:24	A performance improvement	0:24	A performance improvement of enzyme-based electrochemical lactate sensor	0:71	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	2	21	used	used	333:336	arg2	laser					323:327	CO2 laser	319:327	CO2 laser	319:327	CO2 laser was used to convert the polyimide film surface to multilayered LIG.					
36179392	5	22	theme	apparent	935:942	arg1	area					944:947	the apparent area	931:947	the apparent area of PdCu/LIG (1.766 mm2)	931:971	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	2	23	theme	multilayered	379:390	arg1	LIG					392:394	multilayered LIG	379:394	multilayered LIG	379:394	CO2 laser was used to convert the polyimide film surface to multilayered LIG.					
36179392	7	24	theme	calculated	1156:1165	arg1	limit					1167:1171	The calculated limit	1152:1171	The calculated limit of detection	1152:1184	The calculated limit of detection was 0.28 μM.					
36179392	2	25	theme	CO2	319:321	arg1	laser					323:327	CO2 laser	319:327	CO2 laser	319:327	CO2 laser was used to convert the polyimide film surface to multilayered LIG.					
36179392	8	26	theme	sensor	1241:1246	arg1	excellent					1251:1259	excellent	1251:1259	excellent	1251:1259	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	26	theme	sensor	1241:1246	arg1	selectivity					1203:1213	The selectivity	1199:1213	The selectivity of the fabricated lactate sensor	1199:1246	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	3	27	theme	LIG	431:433	arg1	morphology					401:410	morphology	401:410	morphology	401:410	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	3	27	theme	LIG	431:433	arg1	composition					416:426	composition	416:426	composition	416:426	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	0	28	theme	induced	133:139	arg1	electrode					150:158	a laser induced graphene electrode	125:158	a laser induced graphene electrode	125:158	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	3	29	theme	LIG	570:572	arg1	electrode					574:582	the fabricated LIG electrode	555:582	the fabricated LIG electrode	555:582	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	1	30	theme	porous	204:209	arg1	electrodes					240:249	porous laser-induced graphene (LIG) electrodes	204:249	porous laser-induced graphene (LIG) electrodes	204:249	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	4	31	theme	LIG	732:734	arg1	surface					736:742	the LIG surface	728:742	the LIG surface	728:742	PdCu was electrodeposited on the LIG electrode and lactate oxidase (LOx) was immobilized on the LIG surface to create a LOx/PdCu/LIG structure.					
36179392	5	32	theme	PdCu/LIG	952:959	arg1	area					944:947	the apparent area	931:947	the apparent area of PdCu/LIG (1.766 mm2)	931:971	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	1	33	theme	laser-induced	211:223	arg1	electrodes					240:249	porous laser-induced graphene (LIG) electrodes	204:249	porous laser-induced graphene (LIG) electrodes	204:249	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	0	34	theme	electrochemical	42:56	arg1	sensor					66:71	enzyme-based electrochemical lactate sensor	29:71	enzyme-based electrochemical lactate sensor	29:71	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	6	35	with	sensors	1047:1053	arg1	electrode					1077:1085	the LOx/PdCu/LIG electrode	1060:1085	the LOx/PdCu/LIG electrode	1060:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	5	36	theme	electrode	884:892	arg1	area					852:855	the calculated active surface area	822:855	the calculated active surface area of the fabricated PdCu/LIG electrode	822:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	5	36	theme	electrode	884:892	arg1	∼12.8 mm2					898:906	∼12.8 mm2	898:906	∼12.8 mm2	898:906	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	1	37	theme	graphene	225:232	arg1	electrodes					240:249	porous laser-induced graphene (LIG) electrodes	204:249	porous laser-induced graphene (LIG) electrodes	204:249	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	0	38	theme	enzyme-based	29:40	arg1	sensor					66:71	enzyme-based electrochemical lactate sensor	29:71	enzyme-based electrochemical lactate sensor	29:71	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	5	39	theme	fabricated	864:873	arg1	electrode					884:892	the fabricated PdCu/LIG electrode	860:892	the fabricated PdCu/LIG electrode	860:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	0	40	theme	graphene	141:148	arg1	electrode					150:158	a laser induced graphene electrode	125:158	a laser induced graphene electrode	125:158	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	3	41	theme	stacked	611:617	arg1	layers					628:633	porous and stacked graphene layers	600:633	porous and stacked graphene layers	600:633	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	6	42	theme	fabricated	1028:1037	arg1	sensors					1047:1053	the fabricated lactate sensors	1024:1053	the fabricated lactate sensors with the LOx/PdCu/LIG electrode	1024:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	3	43	theme	field-emission	457:470	arg1	microscopy					490:499	field-emission scanning electron microscopy	457:499	field-emission scanning electron microscopy	457:499	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	0	44	theme	sensor	66:71	arg1	improvement					14:24	A performance improvement	0:24	A performance improvement of enzyme-based electrochemical lactate sensor	0:71	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	5	45	theme	PdCu/LIG	875:882	arg1	electrode					884:892	the fabricated PdCu/LIG electrode	860:892	the fabricated PdCu/LIG electrode	860:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	8	46	theme	uric	1333:1336	arg1	acid					1338:1341	uric acid	1333:1341	uric acid	1333:1341	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	3	47	theme	Raman	505:509	arg1	spectroscopy					511:522	Raman spectroscopy	505:522	Raman spectroscopy	505:522	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	0	48	theme	lactate	58:64	arg1	sensor					66:71	enzyme-based electrochemical lactate sensor	29:71	enzyme-based electrochemical lactate sensor	29:71	A performance improvement of enzyme-based electrochemical lactate sensor fabricated by electroplating novel PdCu mediator on a laser induced graphene electrode.					
36179392	6	49	theme	sensors	1047:1053	arg1	μA/mM·cm2					1099:1107	-51.91 μA/mM·cm2	1092:1107	-51.91 μA/mM·cm2 (0.1-5 mM)	1092:1118	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	6	49	theme	sensors	1047:1053	arg1	sensitivities					1007:1019	The measured sensitivities	994:1019	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode	994:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	3	50	theme	porous	600:605	arg1	layers					628:633	porous and stacked graphene layers	600:633	porous and stacked graphene layers	600:633	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	8	51	theme	various	1268:1274	arg1	Na+					1369:1371	Na+	1369:1371	Na+	1369:1371	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	lactose					1344:1350	lactose	1344:1350	lactose	1344:1350	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	acid					1327:1330	ascorbic acid	1318:1330	ascorbic acid	1318:1330	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	sucrose					1353:1359	sucrose	1353:1359	sucrose	1353:1359	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	materials					1300:1308	various potentially interfering materials	1268:1308	various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+	1268:1371	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	acid					1338:1341	uric acid	1333:1341	uric acid	1333:1341	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	51	theme	various	1268:1274	arg1	K+					1362:1363	K+	1362:1363	K+	1362:1363	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	52	theme	lactate	1233:1239	arg1	sensor					1241:1246	the fabricated lactate sensor	1218:1246	the fabricated lactate sensor	1218:1246	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	1	53	theme	LIG	235:237	arg1	electrodes					240:249	porous laser-induced graphene (LIG) electrodes	204:249	porous laser-induced graphene (LIG) electrodes	204:249	A lactate sensor for lactate sensing using porous laser-induced graphene (LIG) electrodes with an electrodeposited PdCu catalyst was developed in this study.					
36179392	5	54	theme	calculated	826:835	arg1	area					852:855	the calculated active surface area	822:855	the calculated active surface area of the fabricated PdCu/LIG electrode	822:892	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	5	54	theme	calculated	826:835	arg1	∼12.8 mm2					898:906	∼12.8 mm2	898:906	∼12.8 mm2	898:906	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	8	55	theme	interfering	1288:1298	arg1	Na+					1369:1371	Na+	1369:1371	Na+	1369:1371	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	lactose					1344:1350	lactose	1344:1350	lactose	1344:1350	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	acid					1327:1330	ascorbic acid	1318:1330	ascorbic acid	1318:1330	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	sucrose					1353:1359	sucrose	1353:1359	sucrose	1353:1359	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	materials					1300:1308	various potentially interfering materials	1268:1308	various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+	1268:1371	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	acid					1338:1341	uric acid	1333:1341	uric acid	1333:1341	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	8	55	theme	interfering	1288:1298	arg1	K+					1362:1363	K+	1362:1363	K+	1362:1363	The selectivity of the fabricated lactate sensor is excellent toward various potentially interfering materials such as ascorbic acid, uric acid, lactose, sucrose, K+ and Na+.					
36179392	6	56	theme	measured	998:1005	arg1	μA/mM·cm2					1099:1107	-51.91 μA/mM·cm2	1092:1107	-51.91 μA/mM·cm2 (0.1-5 mM)	1092:1118	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	6	56	theme	measured	998:1005	arg1	sensitivities					1007:1019	The measured sensitivities	994:1019	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode	994:1085	The measured sensitivities of the fabricated lactate sensors with the LOx/PdCu/LIG electrode were -51.91 μA/mM·cm2 (0.1-5 mM) and -17.18 μA/mM·cm2 (5-30 mM).					
36179392	3	57	theme	graphene	619:626	arg1	layers					628:633	porous and stacked graphene layers	600:633	porous and stacked graphene layers	600:633	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	3	58	theme	scanning	472:479	arg1	microscopy					490:499	field-emission scanning electron microscopy	457:499	field-emission scanning electron microscopy	457:499	The morphology and composition of LIG were analyzed through field-emission scanning electron microscopy and Raman spectroscopy, respectively, to confirm that the fabricated LIG electrode was composed of porous and stacked graphene layers.					
36179392	4	59	theme	LIG	669:671	arg1	electrode					673:681	the LIG electrode	665:681	the LIG electrode	665:681	PdCu was electrodeposited on the LIG electrode and lactate oxidase (LOx) was immobilized on the LIG surface to create a LOx/PdCu/LIG structure.					
36179392	5	60	theme	7.25	988:991	arg1	factor					978:983	a factor	976:983	a factor of 7.25	976:991	According to the Randles-Ševčík equation, the calculated active surface area of the fabricated PdCu/LIG electrode was ∼12.8 mm2, which was larger than the apparent area of PdCu/LIG (1.766 mm2) by a factor of 7.25.					
36179392	2	61	theme	film	363:366	arg1	surface					368:374	the polyimide film surface	349:374	the polyimide film surface	349:374	CO2 laser was used to convert the polyimide film surface to multilayered LIG.					
35504259	7	0	theme	high	1528:1531	arg1	printability					1533:1544	high printability	1528:1544	high printability with increased post-printing stability	1528:1583	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	10	1	theme	bioprinted	2146:2155	arg1	lattice					2157:2163	the 3D bioprinted lattice	2139:2163	the 3D bioprinted lattice	2139:2163	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	2	theme	different	1196:1204	arg1	combinations					1206:1217	the different combinations	1192:1217	the different combinations of Alg-HA gel compositions prepared	1192:1253	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	3	3	theme	multiple	753:760	arg1	mechanisms					775:784	multiple crosslinking mechanisms	753:784	multiple crosslinking mechanisms	753:784	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	8	4	theme	crosslinked	1848:1858	arg1	networks					1860:1867	crosslinked networks	1848:1867	crosslinked networks	1848:1867	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	2	5	theme	bioinks	439:445	arg1	development					410:420	the development	406:420	the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation	406:612	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	5	theme	bioinks	439:445	arg1	challenge					625:633	a challenge	623:633	a challenge	623:633	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	7	6	with	printability	1533:1544	arg1	stability					1575:1583	increased post-printing stability	1551:1583	increased post-printing stability	1551:1583	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	1	7	theme	tissue	338:343	arg1	engineering					345:355	tissue engineering	338:355	tissue engineering	338:355	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	4	8	theme	tunable	944:950	arg1	properties					963:972	tunable mechanical properties	944:972	tunable mechanical properties	944:972	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	11	9	theme	high	2299:2302	arg1	biocompatibility					2304:2319	high biocompatibility	2299:2319	high biocompatibility (>90%)	2299:2326	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	9	theme	high	2299:2302	arg1	%					2325:2325	>90%	2322:2325	>90%	2322:2325	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	6	10	theme	s	1354:1354	arg1	days					1477:1480	>50 days	1473:1480	>50 days	1473:1480	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	10	theme	s	1354:1354	arg1	time					1467:1470	increased degradation time	1445:1470	increased degradation time (>50 days)	1445:1481	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	10	theme	s	1354:1354	arg1	stability					1407:1415	high stability	1402:1415	high stability in various pH solutions	1402:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	10	theme	s	1354:1354	arg1	viscosity					1357:1365	viscosity	1357:1365	viscosity of ∼400 Pa s (at zero shear rate)	1357:1399	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	10	theme	s	1354:1354	arg1	time					1342:1345	a gelation time	1331:1345	a gelation time of ∼60 s	1331:1354	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	1	11	theme	tissue	233:238	arg1	bioprinting					195:205	Three-dimensional (3D) bioprinting	172:205	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure	172:258	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	9	12	theme	5-amino	1916:1922	arg1	acid					1934:1937	5-amino salicylic acid	1916:1937	5-amino salicylic acid	1916:1937	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	3	13	theme	calcium	835:841	arg1	ions					843:846	calcium ions	835:846	calcium ions	835:846	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	10	14	theme	tubular	2169:2175	arg1	constructs					2190:2199	tubular (∼70 layers) constructs	2169:2199	tubular (∼70 layers) constructs	2169:2199	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	1	15	theme	organ	244:248	arg1	structure					250:258	organ structure	244:258	organ structure	244:258	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	9	16	theme	acid	1934:1937	arg1	release					1905:1911	sustained release	1895:1911	sustained release of 5-amino salicylic acid and bovine serum albumin	1895:1962	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	8	17	theme	electron	1739:1746	arg1	microscopy					1748:1757	scanning electron microscopy	1730:1757	The scanning electron microscopy analysis of the 3D constructs and hydrogels	1726:1801	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	7	18	theme	porous	1661:1666	arg1	cube					1668:1671	porous cube	1661:1671	porous cube (∼50 layers)	1661:1684	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	18	theme	porous	1661:1666	arg1	layers					1678:1683	∼50 layers	1674:1683	∼50 layers	1674:1683	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	18	theme	porous	1661:1666	arg1	tube					1641:1644	hollow tube	1634:1644	hollow tube (∼100 layers)	1634:1658	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	9	19	theme	bovine	1943:1948	arg1	albumin					1956:1962	bovine serum albumin	1943:1962	bovine serum albumin	1943:1962	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	6	20	theme	shear	1389:1393	arg1	rate					1395:1398	zero shear rate	1384:1398	zero shear rate	1384:1398	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	9	21	theme	albumin	1956:1962	arg1	release					1905:1911	sustained release	1895:1911	sustained release of 5-amino salicylic acid and bovine serum albumin	1895:1962	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	6	22	from	time	1467:1470	arg1	rate					1395:1398	zero shear rate	1384:1398	zero shear rate	1384:1398	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	22	from	time	1467:1470	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	1	23	theme	Three-dimensional	172:188	arg1	bioprinting					195:205	Three-dimensional (3D) bioprinting	172:205	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure	172:258	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	6	24	dep	gel	1320:1322	arg1	ratio					1307:1311	ratio 50:50	1307:1317	ratio 50:50	1307:1317	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	24	dep	gel	1320:1322	arg1	Alginate-acyl-hydrazide					1266:1288	Alginate-acyl-hydrazide	1266:1288	Alginate-acyl-hydrazide	1266:1288	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	11	25	with	engineering	2523:2533	arg1	properties					2574:2583	tunable properties	2566:2583	tunable properties	2566:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	10	26	theme	secondary	2011:2019	arg1	crosslinking					2021:2032	secondary crosslinking	2011:2032	secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis	2011:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	27	theme	s	1378:1378	arg1	days					1477:1480	>50 days	1473:1480	>50 days	1473:1480	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	27	theme	s	1378:1378	arg1	time					1467:1470	increased degradation time	1445:1470	increased degradation time (>50 days)	1445:1481	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	27	theme	s	1378:1378	arg1	stability					1407:1415	high stability	1402:1415	high stability in various pH solutions	1402:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	27	theme	s	1378:1378	arg1	viscosity					1357:1365	viscosity	1357:1365	viscosity of ∼400 Pa s (at zero shear rate)	1357:1399	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	27	theme	s	1378:1378	arg1	time					1342:1345	a gelation time	1331:1345	a gelation time of ∼60 s	1331:1354	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	5	28	theme	monoaldehyde	1162:1173	arg1	groups					1113:1118	the amine groups	1103:1118	the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA	1103:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	28	theme	monoaldehyde	1162:1173	arg1	acyl-hydrazide					1127:1140	the acyl-hydrazide	1123:1140	the acyl-hydrazide of alginate	1123:1152	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	28	theme	monoaldehyde	1162:1173	arg1	monoaldehyde					1162:1173	the monoaldehyde	1158:1173	the monoaldehyde of the HA	1158:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	8	29	theme	constructs	1778:1787	arg1	analysis					1759:1766	The scanning electron microscopy analysis	1726:1766	The scanning electron microscopy analysis of the 3D constructs and hydrogels	1726:1801	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	10	30	theme	high	2214:2217	arg1	viability					2224:2232	high cell viability	2214:2232	high cell viability	2214:2232	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	8	31	theme	hydrogels	1793:1801	arg1	analysis					1759:1766	The scanning electron microscopy analysis	1726:1766	The scanning electron microscopy analysis of the 3D constructs and hydrogels	1726:1801	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	10	32	theme	calcium	2048:2054	arg1	vitroassays					2074:2084	different calcium concentrations.In vitroassays	2038:2084	different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis	2038:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	0	33	theme	cross-linking	110:122	arg1	mechanisms					124:133	the cross-linking mechanisms	106:133	the cross-linking mechanisms for tissue engineering applications	106:169	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	1	34	theme	self-supporting	210:224	arg1	tissue					233:238	self-supporting stable tissue	210:238	self-supporting stable tissue	210:238	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	11	35	theme	bioprinting	2487:2497	arg1	applications					2499:2510	3D bioprinting applications	2484:2510	3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties	2484:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	10	36	theme	fluorescence	2240:2251	arg1	analysis					2253:2260	fluorescence analysis	2240:2260	fluorescence analysis	2240:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	11	37	theme	hydrogels	2471:2479	arg1	potential					2452:2460	the promising potential	2438:2460	the promising potential of these hydrogels	2438:2479	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	6	38	from	stability	1407:1415	arg1	rate					1395:1398	zero shear rate	1384:1398	zero shear rate	1384:1398	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	38	from	stability	1407:1415	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	5	39	theme	bonds	1082:1086	arg1	presence					1055:1062	the presence	1051:1062	the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA	1051:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	7	40	theme	3D	1606:1607	arg1	structures					1617:1626	the 3D printed structures	1602:1626	the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice)	1602:1723	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	10	41	theme	3D	2143:2144	arg1	lattice					2157:2163	the 3D bioprinted lattice	2139:2163	the 3D bioprinted lattice	2139:2163	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	11	42	theme	macrophage	2380:2389	arg1	infiltration					2391:2402	macrophage infiltration	2380:2402	macrophage infiltration (twofold decrease)	2380:2421	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	42	theme	macrophage	2380:2389	arg1	decrease					2413:2420	twofold decrease	2405:2420	twofold decrease	2405:2420	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	0	43	theme	engineering	146:156	arg1	applications					158:169	tissue engineering applications	139:169	tissue engineering applications	139:169	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	6	44	from	rate	1395:1398	arg1	s					1378:1378	∼400 Pa s	1370:1378	∼400 Pa s (at zero shear rate)	1370:1399	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	44	from	rate	1395:1398	arg1	days					1477:1480	>50 days	1473:1480	>50 days	1473:1480	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	44	from	rate	1395:1398	arg1	stability					1407:1415	high stability	1402:1415	high stability in various pH solutions	1402:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	44	from	rate	1395:1398	arg1	viscosity					1357:1365	viscosity	1357:1365	viscosity of ∼400 Pa s (at zero shear rate)	1357:1399	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	44	from	rate	1395:1398	arg1	time					1342:1345	a gelation time	1331:1345	a gelation time of ∼60 s	1331:1354	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	44	from	rate	1395:1398	arg1	time					1467:1470	increased degradation time	1445:1470	increased degradation time (>50 days)	1445:1481	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	0	45	theme	self-standing	17:29	arg1	constructs					80:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	1	46	theme	regenerative	361:372	arg1	medicine					374:381	regenerative medicine	361:381	regenerative medicine	361:381	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	2	47	theme	mechanical	508:517	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	47	theme	mechanical	508:517	arg1	strength					519:526	tunable mechanical strength	500:526	tunable mechanical strength	500:526	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	0	48	theme	3D-bioprinted	45:57	arg1	constructs					80:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	5	49	theme	acyl-hydrazide	1127:1140	arg1	groups					1113:1118	the amine groups	1103:1118	the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA	1103:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	49	theme	acyl-hydrazide	1127:1140	arg1	acyl-hydrazide					1127:1140	the acyl-hydrazide	1123:1140	the acyl-hydrazide of alginate	1123:1152	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	49	theme	acyl-hydrazide	1127:1140	arg1	monoaldehyde					1162:1173	the monoaldehyde	1158:1173	the monoaldehyde of the HA	1158:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	3	50	theme	hyaluronic	712:721	arg1	acid					723:726	hyaluronic acid	712:726	hyaluronic acid (HA)	712:731	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	3	50	theme	hyaluronic	712:721	arg1	HA					729:730	HA	729:730	HA	729:730	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	2	51	theme	self-standing	425:437	arg1	bioinks					439:445	self-standing bioinks	425:445	self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,	425:566	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	6	52	theme	degradation	1455:1465	arg1	time					1467:1470	increased degradation time	1445:1470	increased degradation time (>50 days)	1445:1481	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	52	theme	degradation	1455:1465	arg1	days					1477:1480	>50 days	1473:1480	>50 days	1473:1480	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	7	53	theme	increased	1551:1559	arg1	stability					1575:1583	increased post-printing stability	1551:1583	increased post-printing stability	1551:1583	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	5	54	theme	alginate	1145:1152	arg1	monoaldehyde					1162:1173	the monoaldehyde	1158:1173	the monoaldehyde of the HA	1158:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	54	theme	alginate	1145:1152	arg1	acyl-hydrazide					1127:1140	the acyl-hydrazide	1123:1140	the acyl-hydrazide of alginate	1123:1152	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	10	55	dep	tubular	2169:2175	arg1	layers					2182:2187	∼70 layers	2178:2187	∼70 layers	2178:2187	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	56	theme	compositions	1233:1244	arg1	combinations					1206:1217	the different combinations	1192:1217	the different combinations of Alg-HA gel compositions prepared	1192:1253	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	11	57	theme	increased	2332:2340	arg1	threefolds					2356:2365	threefolds	2356:2365	threefolds	2356:2365	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	57	theme	increased	2332:2340	arg1	angiogenesis					2342:2353	increased angiogenesis	2332:2353	increased angiogenesis (threefolds)	2332:2366	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	5	58	theme	amine	1107:1111	arg1	groups					1113:1118	the amine groups	1103:1118	the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA	1103:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	58	theme	amine	1107:1111	arg1	acyl-hydrazide					1127:1140	the acyl-hydrazide	1123:1140	the acyl-hydrazide of alginate	1123:1152	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	58	theme	amine	1107:1111	arg1	monoaldehyde					1162:1173	the monoaldehyde	1158:1173	the monoaldehyde of the HA	1158:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	6	59	theme	Alg-HA	1222:1227	arg1	compositions					1233:1244	Alg-HA gel compositions	1222:1244	Alg-HA gel compositions prepared	1222:1253	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	2	60	theme	tunable	500:506	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	60	theme	tunable	500:506	arg1	strength					519:526	tunable mechanical strength	500:526	tunable mechanical strength	500:526	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	61	theme	crosslinking	460:471	arg1	biocompatibility					482:497	biocompatibility	482:497	biocompatibility	482:497	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	61	theme	crosslinking	460:471	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	61	theme	crosslinking	460:471	arg1	strength					519:526	tunable mechanical strength	500:526	tunable mechanical strength	500:526	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	61	theme	crosslinking	460:471	arg1	properties					538:547	other properties	532:547	other properties	532:547	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	1	62	theme	bioprinting	303:313	arg1	system					315:320	extrusion-based bioprinting system	287:320	extrusion-based bioprinting system	287:320	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	10	63	theme	gels	2127:2130	arg1	cytocompatibility					2100:2116	the cytocompatibility	2096:2116	the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis	2096:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	64	theme	Pa	1375:1376	arg1	s					1378:1378	∼400 Pa s	1370:1378	∼400 Pa s (at zero shear rate)	1370:1399	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	7	65	theme	A5H5	1511:1514	arg1	gels					1516:1519	The A5H5 gels	1507:1519	The A5H5 gels	1507:1519	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	2	66	from	development	410:420	arg1	drug					584:587	drug	584:587	drug	584:587	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	66	from	development	410:420	arg1	incorporation					600:612	protein incorporation	592:612	protein incorporation	592:612	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	66	from	development	410:420	arg1	situgelation					570:581	situgelation	570:581	situgelation	570:581	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	3	67	theme	crosslinking	762:773	arg1	mechanisms					775:784	multiple crosslinking mechanisms	753:784	multiple crosslinking mechanisms	753:784	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	6	68	theme	other	1492:1496	arg1	samples					1498:1504	the other samples	1488:1504	the other samples	1488:1504	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	9	69	theme	sustained	1895:1903	arg1	release					1905:1911	sustained release	1895:1911	sustained release of 5-amino salicylic acid and bovine serum albumin	1895:1962	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	1	70	theme	extrusion-based	287:301	arg1	system					315:320	extrusion-based bioprinting system	287:320	extrusion-based bioprinting system	287:320	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	3	71	theme	hydrazide	808:816	arg1	interactions					818:829	hydrazide interactions	808:829	hydrazide interactions	808:829	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	1	72	theme	stable	226:231	arg1	tissue					233:238	self-supporting stable tissue	210:238	self-supporting stable tissue	210:238	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	0	73	theme	constructs	80:89	arg1	Manufacturing					0:12	Manufacturing	0:12	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.	0:170	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	11	74	theme	Alg-HA	2281:2286	arg1	vivostudies					2268:2278	Inin vivostudies	2263:2278	Inin vivostudies	2263:2278	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	74	theme	Alg-HA	2281:2286	arg1	gel					2288:2290	Alg-HA gel	2281:2290	Alg-HA gel	2281:2290	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	6	75	theme	pH	1428:1429	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	5	76	theme	increased	979:987	arg1	nature					997:1002	The increased dynamic nature	975:1002	The increased dynamic nature of the gels	975:1014	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	11	77	theme	3D	2484:2485	arg1	applications					2499:2510	3D bioprinting applications	2484:2510	3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties	2484:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	4	78	theme	mechanical	952:961	arg1	properties					963:972	tunable mechanical properties	944:972	tunable mechanical properties	944:972	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	6	79	theme	A5H5	1260:1263	arg1	gel					1320:1322	the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel	1256:1322	the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel	1256:1322	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	9	80	theme	salicylic	1924:1932	arg1	acid					1934:1937	5-amino salicylic acid	1916:1937	5-amino salicylic acid	1916:1937	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	1	81	theme	structure	250:258	arg1	bioprinting					195:205	Three-dimensional (3D) bioprinting	172:205	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure	172:258	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	11	82	theme	tunable	2566:2572	arg1	properties					2574:2583	tunable properties	2566:2583	tunable properties	2566:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	5	83	theme	gels	1011:1014	arg1	nature					997:1002	The increased dynamic nature	975:1002	The increased dynamic nature of the gels	975:1014	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	6	84	dep	Alginate-acyl-hydrazide	1266:1288	arg1	HA-monoaldehyde					1290:1304	HA-monoaldehyde	1290:1304	HA-monoaldehyde	1290:1304	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	5	85	theme	HA	1182:1183	arg1	monoaldehyde					1162:1173	the monoaldehyde	1158:1173	the monoaldehyde of the HA	1158:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	85	theme	HA	1182:1183	arg1	acyl-hydrazide					1127:1140	the acyl-hydrazide	1123:1140	the acyl-hydrazide of alginate	1123:1152	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	5	86	theme	dynamic	989:995	arg1	nature					997:1002	The increased dynamic nature	975:1002	The increased dynamic nature of the gels	975:1014	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	10	87	theme	different	2038:2046	arg1	vitroassays					2074:2084	different calcium concentrations.In vitroassays	2038:2084	different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis	2038:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	88	theme	gelation	1333:1340	arg1	time					1342:1345	a gelation time	1331:1345	a gelation time of ∼60 s	1331:1354	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	9	89	theme	serum	1950:1954	arg1	albumin					1956:1962	bovine serum albumin	1943:1962	bovine serum albumin	1943:1962	Further, the gels showed sustained release of 5-amino salicylic acid and bovine serum albumin.					
35504259	6	90	theme	various	1420:1426	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	7	91	dep	tube	1641:1644	arg1	e.g.					1629:1632	e.g.	1629:1632	e.g.	1629:1632	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	3	92	theme	hydrogel	663:670	arg1	bioink					672:677	a hydrogel bioink	661:677	a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions	661:846	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	8	93	theme	microscopy	1748:1757	arg1	analysis					1759:1766	The scanning electron microscopy analysis	1726:1766	The scanning electron microscopy analysis of the 3D constructs and hydrogels	1726:1801	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	7	94	theme	post-printing	1561:1573	arg1	stability					1575:1583	increased post-printing stability	1551:1583	increased post-printing stability	1551:1583	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	layers					1652:1657	∼100 layers	1647:1657	∼100 layers	1647:1657	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	meniscus					1703:1710	meniscus	1703:1710	meniscus	1703:1710	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	tube					1641:1644	hollow tube	1634:1644	hollow tube (∼100 layers)	1634:1658	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	lattice					1716:1722	lattice	1716:1722	lattice	1716:1722	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	cube					1668:1671	porous cube	1661:1671	porous cube (∼50 layers)	1661:1684	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	star					1687:1690	star	1687:1690	star	1687:1690	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	95	theme	hollow	1634:1639	arg1	heart-in					1693:1700	heart-in	1693:1700	heart-in	1693:1700	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	10	96	theme	cell	2219:2222	arg1	viability					2224:2232	high cell viability	2214:2232	high cell viability	2214:2232	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	6	97	from	time	1342:1345	arg1	rate					1395:1398	zero shear rate	1384:1398	zero shear rate	1384:1398	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	97	from	time	1342:1345	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	98	theme	increased	1445:1453	arg1	time					1467:1470	increased degradation time	1445:1470	increased degradation time (>50 days)	1445:1481	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	98	theme	increased	1445:1453	arg1	days					1477:1480	>50 days	1473:1480	>50 days	1473:1480	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	7	99	dep	structures	1617:1626	arg1	layers					1652:1657	∼100 layers	1647:1657	∼100 layers	1647:1657	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	meniscus					1703:1710	meniscus	1703:1710	meniscus	1703:1710	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	tube					1641:1644	hollow tube	1634:1644	hollow tube (∼100 layers)	1634:1658	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	lattice					1716:1722	lattice	1716:1722	lattice	1716:1722	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	cube					1668:1671	porous cube	1661:1671	porous cube (∼50 layers)	1661:1684	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	star					1687:1690	star	1687:1690	star	1687:1690	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	7	99	dep	structures	1617:1626	arg1	heart-in					1693:1700	heart-in	1693:1700	heart-in	1693:1700	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	8	100	theme	3D	1775:1776	arg1	constructs					1778:1787	the 3D constructs	1771:1787	the 3D constructs	1771:1787	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	8	101	link	crosslinked	1848:1858	arg1	networks					1860:1867	crosslinked networks	1848:1867	crosslinked networks	1848:1867	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	2	102	theme	protein	592:598	arg1	incorporation					600:612	protein incorporation	592:612	protein incorporation	592:612	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	7	103	theme	printed	1609:1615	arg1	structures					1617:1626	the 3D printed structures	1602:1626	the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice)	1602:1723	The A5H5 gels showed high printability with increased post-printing stability as observed from the 3D printed structures (e.g. hollow tube (∼100 layers), porous cube (∼50 layers), star, heart-in, meniscus and lattice).					
35504259	1	104	dep	engineering	345:355	arg1	applications					383:394	applications	383:394	applications	383:394	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	4	105	with	dynamic	879:885	arg1	properties					963:972	tunable mechanical properties	944:972	tunable mechanical properties	944:972	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	4	105	with	dynamic	879:885	arg1	biocompatibility					923:938	exceptional biocompatibility	911:938	exceptional biocompatibility	911:938	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	0	106	theme	tissue	139:144	arg1	applications					158:169	tissue engineering applications	139:169	tissue engineering applications	139:169	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	5	107	theme	acyl-hydrazone	1067:1080	arg1	bonds					1082:1086	acyl-hydrazone bonds	1067:1086	acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA	1067:1183	The increased dynamic nature of the gels is mainly chemically attributed to the presence of acyl-hydrazone bonds formed between the amine groups of the acyl-hydrazide of alginate and the monoaldehyde of the HA.					
35504259	8	108	theme	interconnected	1814:1827	arg1	∼181µm					1836:1841	∼181µm	1836:1841	∼181µm	1836:1841	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	8	108	theme	interconnected	1814:1827	arg1	pores					1829:1833	the interconnected pores	1810:1833	the interconnected pores (∼181µm)	1810:1842	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	11	109	theme	Inin	2263:2266	arg1	vivostudies					2268:2278	Inin vivostudies	2263:2278	Inin vivostudies	2263:2278	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	109	theme	Inin	2263:2266	arg1	gel					2288:2290	Alg-HA gel	2281:2290	Alg-HA gel	2281:2290	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	110	theme	tissue	2516:2521	arg1	engineering					2523:2533	tissue engineering	2516:2533	tissue engineering	2516:2533	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	1	111	dep	Three-dimensional	172:188	arg1	3D					191:192	3D	191:192	3D	191:192	Three-dimensional (3D) bioprinting of self-supporting stable tissue and organ structure is critically important in extrusion-based bioprinting system, especially for tissue engineering and regenerative medicine applications.					
35504259	11	112	theme	regenerative	2539:2550	arg1	medicine					2552:2559	regenerative medicine	2539:2559	regenerative medicine with tunable properties	2539:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	113	theme	twofold	2405:2411	arg1	infiltration					2391:2402	macrophage infiltration	2380:2402	macrophage infiltration (twofold decrease)	2380:2421	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	113	theme	twofold	2405:2411	arg1	decrease					2413:2420	twofold decrease	2405:2420	twofold decrease	2405:2420	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	11	114	with	medicine	2552:2559	arg1	properties					2574:2583	tunable properties	2566:2583	tunable properties	2566:2583	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	0	115	theme	multi-layered	31:43	arg1	constructs					80:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	2	116	theme	other	532:536	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	116	theme	other	532:536	arg1	properties					538:547	other properties	532:547	other properties	532:547	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	8	117	theme	scanning	1730:1737	arg1	microscopy					1748:1757	scanning electron microscopy	1730:1757	The scanning electron microscopy analysis of the 3D constructs and hydrogels	1726:1801	The scanning electron microscopy analysis of the 3D constructs and hydrogels showed the interconnected pores (∼181µm) and crosslinked networks.					
35504259	0	118	theme	alginate-hyaluronate	59:78	arg1	constructs					80:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs	17:89	Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.					
35504259	6	119	theme	high	1402:1405	arg1	stability					1407:1415	high stability	1402:1415	high stability in various pH solutions	1402:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	3	120	dep	acyl-hydrazone	792:805	arg1	i.e.					787:790	i.e.	787:790	i.e.	787:790	In this study, we report a hydrogel bioink prepared from alginate (Alg) and hyaluronic acid (HA) crosslinked through multiple crosslinking mechanisms, i.e. acyl-hydrazone, hydrazide interactions and calcium ions.					
35504259	4	121	theme	exceptional	911:921	arg1	biocompatibility					923:938	exceptional biocompatibility	911:938	exceptional biocompatibility	911:938	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	2	122	with	bioinks	439:445	arg1	biocompatibility					482:497	biocompatibility	482:497	biocompatibility	482:497	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	122	with	bioinks	439:445	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	122	with	bioinks	439:445	arg1	strength					519:526	tunable mechanical strength	500:526	tunable mechanical strength	500:526	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	122	with	bioinks	439:445	arg1	properties					538:547	other properties	532:547	other properties	532:547	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	6	123	theme	gel	1229:1231	arg1	compositions					1233:1244	Alg-HA gel compositions	1222:1244	Alg-HA gel compositions prepared	1222:1253	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	4	124	theme	Alg-HA	855:860	arg1	gels					862:865	These Alg-HA gels	849:865	These Alg-HA gels	849:865	These Alg-HA gels were highly dynamic and shear-thinning with exceptional biocompatibility and tunable mechanical properties.					
35504259	11	125	theme	promising	2442:2450	arg1	potential					2452:2460	the promising potential	2438:2460	the promising potential of these hydrogels	2438:2479	Inin vivostudies, Alg-HA gel showed high biocompatibility (>90%) and increased angiogenesis (threefolds) and reduced macrophage infiltration (twofold decrease), demonstrating the promising potential of these hydrogels in 3D bioprinting applications for tissue engineering and regenerative medicine with tunable properties.					
35504259	6	126	from	viscosity	1357:1365	arg1	rate					1395:1398	zero shear rate	1384:1398	zero shear rate	1384:1398	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	6	126	from	viscosity	1357:1365	arg1	solutions					1431:1439	various pH solutions	1420:1439	various pH solutions	1420:1439	Among the different combinations of Alg-HA gel compositions prepared, the A5H5 (Alginate-acyl-hydrazide:HA-monoaldehyde, ratio 50:50) gel showed a gelation time of ∼60 s, viscosity of ∼400 Pa s (at zero shear rate), high stability in various pH solutions and increased degradation time (>50 days) than the other samples.					
35504259	10	127	theme	concentrations.In	2056:2072	arg1	vitroassays					2074:2084	different calcium concentrations.In vitroassays	2038:2084	different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis	2038:2260	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
35504259	2	128	theme	desired	452:458	arg1	biocompatibility					482:497	biocompatibility	482:497	biocompatibility	482:497	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	128	theme	desired	452:458	arg1	density					473:479	desired crosslinking density	452:479	desired crosslinking density	452:479	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	128	theme	desired	452:458	arg1	strength					519:526	tunable mechanical strength	500:526	tunable mechanical strength	500:526	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	2	128	theme	desired	452:458	arg1	properties					538:547	other properties	532:547	other properties	532:547	However, the development of self-standing bioinks with desired crosslinking density, biocompatibility, tunable mechanical strength and other properties like self-healing,in situgelation, drug or protein incorporation is still a challenge.					
35504259	10	129	theme	mechanical	1975:1984	arg1	properties					1986:1995	the mechanical properties	1971:1995	the mechanical properties	1971:1995	Also, the mechanical properties were tuned by secondary crosslinking via different calcium concentrations.In vitroassays confirmed the cytocompatibility of these gels, where the 3D bioprinted lattice and tubular (∼70 layers) constructs demonstrated high cell viability under fluorescence analysis.					
36398536	0	0	theme	Lesions	75:81	arg1	Treatment					56:64	Treatment	56:64	Treatment of Brain Lesions	56:81	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions.					
36398536	7	1	theme	technology	1407:1416	arg1	progresses					1418:1427	the technology progresses	1403:1427	the technology progresses toward potential application in humans	1403:1466	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	7	1	theme	technology	1407:1416	arg1	experimentation					1366:1380	additional experimentation	1355:1380	additional experimentation in larger animals	1355:1398	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	0	2	theme	Brain	69:73	arg1	Lesions					75:81	Brain Lesions	69:81	Brain Lesions	69:81	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions.					
36398536	4	3	theme	grafted	849:855	arg1	gelatin					857:863	dopamine grafted gelatin	840:863	dopamine grafted gelatin (Gel-Dopa)	840:874	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	3	theme	grafted	849:855	arg1	Gel-Dopa					866:873	Gel-Dopa	866:873	Gel-Dopa	866:873	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	5	4	theme	HA-PBA/Gel-Dopa	882:896	arg1	hydrogel					898:905	This HA-PBA/Gel-Dopa hydrogel	877:905	This HA-PBA/Gel-Dopa hydrogel	877:905	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	5	5	theme	rapid	978:982	arg1	hemostasis					984:993	rapid hemostasis	978:993	rapid hemostasis	978:993	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	4	6	theme	dynamic	747:753	arg1	bonds					770:774	dynamic boronate ester bonds	747:774	dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa)	747:874	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	6	7	theme	injectable	1111:1120	arg1	hydrogel					1122:1129	the multi-functional injectable hydrogel	1090:1129	the multi-functional injectable hydrogel	1090:1129	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	3	8	theme	parenchyma	704:713	arg1	viscoelasticity					672:686	viscoelasticity	672:686	viscoelasticity	672:686	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	3	8	theme	parenchyma	704:713	arg1	stiffness					658:666	stiffness	658:666	stiffness	658:666	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	7	9	theme	potential	1436:1444	arg1	application					1446:1456	potential application	1436:1456	potential application in humans	1436:1466	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	2	10	theme	neural	315:320	arg1	tissue					322:327	neural tissue	315:327	neural tissue	315:327	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	6	11	theme	neural	1151:1156	arg1	infiltration					1163:1174	neural cell infiltration	1151:1174	neural cell infiltration	1151:1174	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	3	12	theme	viscoelasticity	461:475	arg1	mismatch					421:428	the mismatch	417:428	the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma	417:521	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	2	13	theme	tissue	266:271	arg1	healing					221:227	healing	221:227	healing of lesions	221:238	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	2	13	theme	tissue	266:271	arg1	health					244:249	health	244:249	health of surrounding tissue	244:271	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	7	14	theme	lesion	1326:1331	arg1	healing					1333:1339	brain lesion healing	1320:1339	brain lesion healing	1320:1339	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	3	15	theme	native	691:696	arg1	parenchyma					704:713	native brain parenchyma	691:713	native brain parenchyma	691:713	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	4	16	theme	acid	798:801	arg1	HA-PBA					828:833	HA-PBA	828:833	HA-PBA	828:833	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	16	theme	acid	798:801	arg1	acid					822:825	phenylboronic acid grafted hyaluronic acid	784:825	phenylboronic acid grafted hyaluronic acid (HA-PBA)	784:834	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	2	17	theme	surrounding	254:264	arg1	tissue					266:271	surrounding tissue	254:271	surrounding tissue	254:271	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	6	18	theme	mouse	1060:1064	arg1	model					1066:1070	an in vivo mouse model	1049:1070	an in vivo mouse model of brain lesions	1049:1087	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	6	19	theme	in	1052:1053	arg1	model					1066:1070	an in vivo mouse model	1049:1070	an in vivo mouse model of brain lesions	1049:1087	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	0	20	theme	ECM-Mimicking	3:15	arg1	Hydrogel					43:50	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel	0:50	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions	0:81	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions.					
36398536	3	21	theme	brain	698:702	arg1	parenchyma					704:713	native brain parenchyma	691:713	native brain parenchyma	691:713	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	4	22	theme	dopamine	840:847	arg1	gelatin					857:863	dopamine grafted gelatin	840:863	dopamine grafted gelatin (Gel-Dopa)	840:874	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	22	theme	dopamine	840:847	arg1	Gel-Dopa					866:873	Gel-Dopa	866:873	Gel-Dopa	866:873	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	7	23	theme	matrix-mimicking	1284:1299	arg1	viscoelasticity					1301:1315	extracellular matrix-mimicking viscoelasticity	1270:1315	extracellular matrix-mimicking viscoelasticity	1270:1315	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	3	24	dep	stiffness	658:666	arg1	the					654:656	the	654:656	the	654:656	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	1	25	theme	Brain	84:88	arg1	lesions					90:96	Brain lesions	84:96	Brain lesions	84:96	Brain lesions can arise from traumatic brain injury, infection, and craniotomy.					
36398536	0	26	dep	ECM-Mimicking	3:15	arg1	Viscoelastic					30:41	Viscoelastic	30:41	Viscoelastic	30:41	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions.					
36398536	0	26	dep	ECM-Mimicking	3:15	arg1	Injectable					18:27	Injectable	18:27	Injectable	18:27	An ECM-Mimicking, Injectable, Viscoelastic Hydrogel for Treatment of Brain Lesions.					
36398536	5	27	theme	lesion	932:937	arg1	cavity					939:944	a lesion cavity	930:944	a lesion cavity	930:944	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	5	28	theme	high	996:999	arg1	adhesion					1008:1015	high tissue adhesion	996:1015	high tissue adhesion	996:1015	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	3	29	theme	stiffness	446:454	arg1	mismatch					421:428	the mismatch	417:428	the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma	417:521	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	6	30	theme	lesions	1081:1087	arg1	model					1066:1070	an in vivo mouse model	1049:1070	an in vivo mouse model of brain lesions	1049:1087	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	4	31	theme	ester	764:768	arg1	bonds					770:774	dynamic boronate ester bonds	747:774	dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa)	747:874	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	6	32	theme	cell	1158:1161	arg1	infiltration					1163:1174	neural cell infiltration	1151:1174	neural cell infiltration	1151:1174	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	2	33	theme	cellular	283:290	arg1	ingrowth					292:299	cellular ingrowth	283:299	cellular ingrowth	283:299	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	7	34	from	experimentation	1366:1380	arg1	animals					1392:1398	larger animals	1385:1398	larger animals	1385:1398	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	7	35	theme	extracellular	1270:1282	arg1	viscoelasticity					1301:1315	extracellular matrix-mimicking viscoelasticity	1270:1315	extracellular matrix-mimicking viscoelasticity	1270:1315	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	4	36	theme	hyaluronic	811:820	arg1	HA-PBA					828:833	HA-PBA	828:833	HA-PBA	828:833	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	36	theme	hyaluronic	811:820	arg1	acid					822:825	phenylboronic acid grafted hyaluronic acid	784:825	phenylboronic acid grafted hyaluronic acid (HA-PBA)	784:834	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	3	37	theme	composition	433:443	arg1	mismatch					421:428	the mismatch	417:428	the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma	417:521	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	5	38	with	manner	966:971	arg1	hemostasis					984:993	rapid hemostasis	978:993	rapid hemostasis	978:993	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	5	38	with	manner	966:971	arg1	self-healing					1032:1043	efficient self-healing	1022:1043	efficient self-healing	1022:1043	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	5	38	with	manner	966:971	arg1	adhesion					1008:1015	high tissue adhesion	996:1015	high tissue adhesion	996:1015	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	4	39	theme	grafted	803:809	arg1	HA-PBA					828:833	HA-PBA	828:833	HA-PBA	828:833	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	39	theme	grafted	803:809	arg1	acid					822:825	phenylboronic acid grafted hyaluronic acid	784:825	phenylboronic acid grafted hyaluronic acid (HA-PBA)	784:834	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	6	40	theme	glial	1203:1207	arg1	scars					1209:1213	glial scars	1203:1213	glial scars	1203:1213	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	7	41	from	role	1261:1264	arg1	healing					1333:1339	brain lesion healing	1320:1339	brain lesion healing	1320:1339	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	6	42	theme	multi-functional	1094:1109	arg1	hydrogel					1122:1129	the multi-functional injectable hydrogel	1090:1129	the multi-functional injectable hydrogel	1090:1129	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	7	43	from	application	1446:1456	arg1	humans					1461:1466	humans	1461:1466	humans	1461:1466	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	6	44	dep	in	1052:1053	arg1	vivo					1055:1058	vivo	1055:1058	vivo	1055:1058	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	7	45	theme	additional	1355:1364	arg1	progresses					1418:1427	the technology progresses	1403:1427	the technology progresses toward potential application in humans	1403:1466	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	7	45	theme	additional	1355:1364	arg1	experimentation					1366:1380	additional experimentation	1355:1380	additional experimentation in larger animals	1355:1398	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	4	46	theme	phenylboronic	784:796	arg1	HA-PBA					828:833	HA-PBA	828:833	HA-PBA	828:833	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	4	46	theme	phenylboronic	784:796	arg1	acid					822:825	phenylboronic acid grafted hyaluronic acid	784:825	phenylboronic acid grafted hyaluronic acid (HA-PBA)	784:834	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	5	47	theme	efficient	1022:1030	arg1	self-healing					1032:1043	efficient self-healing	1022:1043	efficient self-healing	1022:1043	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	5	48	theme	tissue	1001:1006	arg1	adhesion					1008:1015	high tissue adhesion	996:1015	high tissue adhesion	996:1015	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	1	49	theme	traumatic	113:121	arg1	injury					129:134	traumatic brain injury	113:134	traumatic brain injury	113:134	Brain lesions can arise from traumatic brain injury, infection, and craniotomy.					
36398536	7	50	theme	larger	1385:1390	arg1	animals					1392:1398	larger animals	1385:1398	larger animals	1385:1398	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	4	51	theme	boronate	755:762	arg1	bonds					770:774	dynamic boronate ester bonds	747:774	dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa)	747:874	The hydrogel is crosslinked by dynamic boronate ester bonds between phenylboronic acid grafted hyaluronic acid (HA-PBA) and dopamine grafted gelatin (Gel-Dopa).					
36398536	5	52	theme	shear-thinning	951:964	arg1	manner					966:971	a shear-thinning manner	949:971	a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing	949:1043	This HA-PBA/Gel-Dopa hydrogel could be injected into a lesion cavity in a shear-thinning manner with rapid hemostasis, high tissue adhesion, and efficient self-healing.					
36398536	1	53	theme	brain	123:127	arg1	injury					129:134	traumatic brain injury	113:134	traumatic brain injury	113:134	Brain lesions can arise from traumatic brain injury, infection, and craniotomy.					
36398536	6	54	located	found	1134:1138	arg1	model					1066:1070	an in vivo mouse model	1049:1070	an in vivo mouse model of brain lesions	1049:1087	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	6	54	located	found	1134:1138	arg2	hydrogel					1122:1129	the multi-functional injectable hydrogel	1090:1129	the multi-functional injectable hydrogel	1090:1129	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	2	55	theme	injectable	173:182	arg1	hydrogels					184:192	injectable hydrogels	173:192	injectable hydrogels	173:192	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	3	56	theme	self-healing	585:596	arg1	hydrogel					598:605	a self-healing hydrogel	583:605	a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma	583:713	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	6	57	theme	brain	1075:1079	arg1	lesions					1081:1087	brain lesions	1075:1087	brain lesions	1075:1087	In an in vivo mouse model of brain lesions, the multi-functional injectable hydrogel is found to support neural cell infiltration, decrease astrogliosis and glial scars, and close the lesions.					
36398536	7	58	theme	brain	1320:1324	arg1	healing					1333:1339	brain lesion healing	1320:1339	brain lesion healing	1320:1339	The results suggest a role for extracellular matrix-mimicking viscoelasticity in brain lesion healing, and motivate additional experimentation in larger animals as the technology progresses toward potential application in humans.					
36398536	2	59	theme	lesions	232:238	arg1	healing					221:227	healing	221:227	healing of lesions	221:238	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	2	59	theme	lesions	232:238	arg1	health					244:249	health	244:249	health of surrounding tissue	244:271	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	3	60	theme	brain	506:510	arg1	parenchyma					512:521	the brain parenchyma	502:521	the brain parenchyma	502:521	It is hypothesized that these challenges arise in part from the mismatch of composition, stiffness, and viscoelasticity between the hydrogel and the brain parenchyma, and this hypothesis is tested by developing and evaluating a self-healing hydrogel that not only mimics the composition, but also the stiffness and viscoelasticity of native brain parenchyma.					
36398536	2	61	dep	show	194:197	arg1	enabling					274:281	enabling	274:281	enabling cellular ingrowth	274:299	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
36398536	2	61	dep	show	194:197	arg1	restoring					305:313	restoring	305:313	restoring neural tissue	305:327	Although injectable hydrogels show promise for promoting healing of lesions and health of surrounding tissue, enabling cellular ingrowth and restoring neural tissue continue to be challenging.					
35981679	1	0	theme	selenium	170:177	arg1	SeMPs					195:199	SeMPs	195:199	SeMPs	195:199	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	1	0	theme	selenium	170:177	arg1	microparticles					179:192	selenium microparticles	170:192	selenium microparticles (SeMPs)	170:200	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	6	1	theme	inhibition	1023:1032	arg1	diameter					1039:1046	the inhibition zone diameter	1019:1046	the inhibition zone diameter	1019:1046	The antibacterial property of the membrane was determined by the inhibition zone diameter.					
35981679	5	2	theme	similar	923:929	arg1	methods					949:955	similar advanced analysis methods	923:955	similar advanced analysis methods	923:955	SeMPs-GO was additionally incorporated onto chitosan (CTS) to collect the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods.					
35981679	5	3	theme	advanced	931:938	arg1	methods					949:955	similar advanced analysis methods	923:955	similar advanced analysis methods	923:955	SeMPs-GO was additionally incorporated onto chitosan (CTS) to collect the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods.					
35981679	6	4	theme	zone	1034:1037	arg1	diameter					1039:1046	the inhibition zone diameter	1019:1046	the inhibition zone diameter	1019:1046	The antibacterial property of the membrane was determined by the inhibition zone diameter.					
35981679	7	5	theme	degradation	1149:1159	arg1	sign					1141:1144	no sign	1138:1144	no sign of degradation	1138:1159	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	4	6	theme	fungal	783:788	arg1	activity					790:797	fungal activity	783:797	fungal activity	783:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	1	7	theme	effective	282:290	arg1	agent					301:305	an effective reducing agent	279:305	an effective reducing agent	279:305	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	1	7	theme	effective	282:290	arg1	catappa					253:259	the Terminalia catappa	238:259	the Terminalia catappa leaves extract	238:274	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	0	8	theme	graphene	109:116	arg1	oxide					118:122	graphene oxide	109:122	graphene oxide	109:122	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	4	9	theme	Gram-negative	722:734	arg1	strains					745:751	both Gram-positive and Gram-negative bacteria strains	699:751	both Gram-positive and Gram-negative bacteria strains	699:751	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	1	10	theme	reducing	292:299	arg1	agent					301:305	an effective reducing agent	279:305	an effective reducing agent	279:305	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	1	10	theme	reducing	292:299	arg1	catappa					253:259	the Terminalia catappa	238:259	the Terminalia catappa leaves extract	238:274	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	0	11	theme	antibacterial	128:140	arg1	application					142:152	antibacterial application	128:152	antibacterial application	128:152	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	5	12	theme	analysis	940:947	arg1	methods					949:955	similar advanced analysis methods	923:955	similar advanced analysis methods	923:955	SeMPs-GO was additionally incorporated onto chitosan (CTS) to collect the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods.					
35981679	4	13	theme	restrained	764:773	arg1	%					778:778	restrained 50 %	764:778	99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	686:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	4	13	theme	restrained	764:773	arg1	activity					790:797	fungal activity	783:797	fungal activity	783:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	3	14	theme	antibacterial	548:560	arg1	performance					562:572	the antibacterial performance	544:572	the antibacterial performance of the composites	544:590	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	2	15	theme	ex-situ	403:409	arg1	technique					411:419	the ex-situ technique	399:419	the ex-situ technique to obtain the SeMPs-GO composite	399:452	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	4	16	theme	activity	790:797	arg1	activity					790:797	fungal activity	783:797	fungal activity	783:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	4	16	theme	activity	790:797	arg1	%					778:778	restrained 50 %	764:778	99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	686:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	4	16	theme	activity	790:797	arg1	%					689:689	99 %	686:689	99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	686:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	7	17	theme	38 N/mm2	1218:1225	arg1	strength					1206:1213	a tensile strength	1196:1213	a tensile strength of 38 N/mm2	1196:1225	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	7	17	theme	38 N/mm2	1218:1225	arg1	260 °C					1184:1189	260 °C	1184:1189	260 °C	1184:1189	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	9	18	used	utilized	1373:1380	arg2	membrane					1345:1352	The obtained membrane	1332:1352	The obtained membrane	1332:1352	The obtained membrane can potentially be utilized for medical and food applications.					
35981679	6	19	theme	membrane	992:999	arg1	property					976:983	The antibacterial property	958:983	The antibacterial property of the membrane	958:999	The antibacterial property of the membrane was determined by the inhibition zone diameter.					
35981679	2	20	theme	graphene	339:346	arg1	oxide					348:352	graphene oxide	339:352	graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite	339:452	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	8	21	theme	immersion	1275:1283	arg1	6 h					1268:1270	6 h	1268:1270	6 h of immersion in water, which was stable after 72 h (153 %)	1268:1329	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	0	22	theme	Green	0:4	arg1	synthesis					6:14	Green synthesis	0:14	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles	0:97	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	5	23	theme	SeMPs-GO/CTS	874:885	arg1	membrane					887:894	the SeMPs-GO/CTS membrane	870:894	the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods	870:955	SeMPs-GO was additionally incorporated onto chitosan (CTS) to collect the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods.					
35981679	2	24	dep	oxide	348:352	arg1	GO					355:356	GO	355:356	GO	355:356	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	2	25	theme	ultrasound	382:391	arg1	assistance					368:377	the assistance	364:377	the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite	364:452	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	0	26	theme	chitosan-based	19:32	arg1	membrane					34:41	chitosan-based membrane	19:41	chitosan-based membrane modified with uniformly micro-sizing selenium particles	19:97	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	3	27	theme	composites	581:590	arg1	performance					562:572	the antibacterial performance	544:572	the antibacterial performance of the composites	544:590	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	2	28	theme	SeMPs-GO	435:442	arg1	composite					444:452	the SeMPs-GO composite	431:452	the SeMPs-GO composite	431:452	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	9	29	theme	obtained	1336:1343	arg1	membrane					1345:1352	The obtained membrane	1332:1352	The obtained membrane	1332:1352	The obtained membrane can potentially be utilized for medical and food applications.					
35981679	4	30	theme	50 	775:777	arg1	%					778:778	restrained 50 %	764:778	99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	686:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	4	30	theme	50 	775:777	arg1	activity					790:797	fungal activity	783:797	fungal activity	783:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	4	31	theme	bacteria	736:743	arg1	strains					745:751	both Gram-positive and Gram-negative bacteria strains	699:751	both Gram-positive and Gram-negative bacteria strains	699:751	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	2	32	with	oxide	348:352	arg1	assistance					368:377	the assistance	364:377	the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite	364:452	SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite.					
35981679	3	33	theme	density	622:628	arg1	method					630:635	the optical density method	610:635	the optical density method	610:635	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	4	34	theme	%	689:689	arg1	inhibition					672:681	an inhibition	669:681	an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	669:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	0	35	theme	membrane	34:41	arg1	synthesis					6:14	Green synthesis	0:14	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles	0:97	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	7	36	theme	mechanical	1102:1111	arg1	characteristics					1113:1127	good thermal and mechanical characteristics	1085:1127	good thermal and mechanical characteristics	1085:1127	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	8	37	theme	swelling	1232:1239	arg1	degree					1241:1246	The swelling degree	1228:1246	The swelling degree	1228:1246	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	8	38	from	immersion	1275:1283	arg1	water					1288:1292	water	1288:1292	water	1288:1292	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	7	39	theme	good	1085:1088	arg1	characteristics					1113:1127	good thermal and mechanical characteristics	1085:1127	good thermal and mechanical characteristics	1085:1127	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	1	40	dep	catappa	253:259	arg1	leaves					261:266	leaves	261:266	leaves extract	261:274	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	3	41	theme	modern	509:514	arg1	methods					527:533	modern analytical methods	509:533	modern analytical methods	509:533	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	7	42	theme	thermal	1090:1096	arg1	characteristics					1113:1127	good thermal and mechanical characteristics	1085:1127	good thermal and mechanical characteristics	1085:1127	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	3	43	theme	optical	614:620	arg1	method					630:635	the optical density method	610:635	the optical density method	610:635	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	8	44	from	6 h	1268:1270	arg1	water					1288:1292	water	1288:1292	water	1288:1292	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	3	45	theme	analytical	516:525	arg1	methods					527:533	modern analytical methods	509:533	modern analytical methods	509:533	SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method.					
35981679	6	46	theme	antibacterial	962:974	arg1	property					976:983	The antibacterial property	958:983	The antibacterial property of the membrane	958:999	The antibacterial property of the membrane was determined by the inhibition zone diameter.					
35981679	4	47	theme	%	778:778	arg1	inhibition					672:681	an inhibition	669:681	an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity	669:797	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	1	48	theme	Terminalia	242:251	arg1	agent					301:305	an effective reducing agent	279:305	an effective reducing agent	279:305	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	1	48	theme	Terminalia	242:251	arg1	catappa					253:259	the Terminalia catappa	238:259	the Terminalia catappa leaves extract	238:274	In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent.					
35981679	9	49	theme	medical	1386:1392	arg1	applications					1403:1414	medical and food applications	1386:1414	medical and food applications	1386:1414	The obtained membrane can potentially be utilized for medical and food applications.					
35981679	0	50	theme	selenium	80:87	arg1	particles					89:97	uniformly micro-sizing selenium particles	57:97	uniformly micro-sizing selenium particles	57:97	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	8	51	dep	stable	1305:1310	arg1	%					1328:1328	153 %	1324:1328	153 %	1324:1328	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	4	52	theme	Gram-positive	704:716	arg1	strains					745:751	both Gram-positive and Gram-negative bacteria strains	699:751	both Gram-positive and Gram-negative bacteria strains	699:751	Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity.					
35981679	0	53	theme	micro-sizing	67:78	arg1	particles					89:97	uniformly micro-sizing selenium particles	57:97	uniformly micro-sizing selenium particles	57:97	Green synthesis of chitosan-based membrane modified with uniformly micro-sizing selenium particles decorated graphene oxide for antibacterial application.					
35981679	7	54	theme	tensile	1198:1204	arg1	strength					1206:1213	a tensile strength	1196:1213	a tensile strength of 38 N/mm2	1196:1225	Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2.					
35981679	8	55	from	water	1288:1292	arg1	6 h					1268:1270	6 h	1268:1270	6 h of immersion in water, which was stable after 72 h (153 %)	1268:1329	The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %).					
35981679	9	56	theme	food	1398:1401	arg1	applications					1403:1414	medical and food applications	1386:1414	medical and food applications	1386:1414	The obtained membrane can potentially be utilized for medical and food applications.					
36988943	3	0	theme	parallel	685:692	arg1	asymmetry					652:660	asymmetry	652:660	asymmetry both perpendicular and parallel to the plane of the lipid bilayer	652:726	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	2	1	theme	outer	421:425	arg1	leaflets					427:434	the inner and outer leaflets	407:434	the inner and outer leaflets of lipid bilayer	407:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	2	from	differences	392:402	arg1	leaflets					427:434	the inner and outer leaflets	407:434	the inner and outer leaflets of lipid bilayer	407:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	6	3	theme	lipid	1137:1141	arg1	distribution					1143:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	3	4	theme	perpendicular	667:679	arg1	asymmetry					652:660	asymmetry	652:660	asymmetry both perpendicular and parallel to the plane of the lipid bilayer	652:726	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	6	5	theme	lipid	1176:1180	arg1	classes					1182:1188	all lipid classes	1172:1188	all lipid classes	1172:1188	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	6	5	theme	lipid	1176:1180	arg1	cells					1191:1195	cells	1191:1195	cells	1191:1195	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	4	6	theme	biological	738:747	arg1	membranes					749:757	biological membranes	738:757	biological membranes	738:757	Although biological membranes are almost universally asymmetric however the asymmetry is not absolute since only drastic difference in the number of lipids per leaflet is found and symmetric arrangements are possible.					
36988943	3	7	theme	lipid	529:533	arg1	molecules					535:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	3	8	theme	different	500:508	arg1	molecules					535:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	order					339:343	lipid packing order	325:343	lipid packing order	325:343	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	interactions					378:389	H-bonding interactions	368:389	H-bonding interactions	368:389	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	charge					346:351	charge	346:351	charge	346:351	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	head					290:293	lipid head and acyl group	284:308	head	290:293	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	hydration					354:362	hydration	354:362	hydration	354:362	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	9	dep	compositional	269:281	arg1	group					304:308	lipid head and acyl group	284:308	group	304:308	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	1	10	theme	membrane	122:129	arg1	sides					113:117	the two sides	105:117	the two sides of membrane	105:129	Membrane asymmetry means that the two sides of membrane are structurally, physically and functionally different.					
36988943	2	11	theme	bilayer	445:451	arg1	leaflets					427:434	the inner and outer leaflets	407:434	the inner and outer leaflets of lipid bilayer	407:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	0	12	dep	membrane	56:63	arg1	the					52:54	the	52:54	the	52:54	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	3	13	theme	lipid	714:718	arg1	bilayer					720:726	the lipid bilayer	710:726	the lipid bilayer	710:726	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	4	14	theme	drastic	842:848	arg1	difference					850:859	only drastic difference	837:859	only drastic difference in the number of lipids per leaflet	837:895	Although biological membranes are almost universally asymmetric however the asymmetry is not absolute since only drastic difference in the number of lipids per leaflet is found and symmetric arrangements are possible.					
36988943	0	15	theme	symmetry	36:43	arg1	challenge					14:22	challenge	14:22	challenge	14:22	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	0	15	theme	symmetry	36:43	arg1	power					4:8	power	4:8	power	4:8	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	2	16	theme	lipid	284:288	arg1	head					290:293	lipid head and acyl group	284:308	head	290:293	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	5	17	theme	structural	1090:1099	arg1	properties					1101:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	2	18	theme	packing	331:337	arg1	order					339:343	lipid packing order	325:343	lipid packing order	325:343	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	3	19	theme	bilayer	720:726	arg1	plane					701:705	the plane	697:705	the plane of the lipid bilayer	697:726	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	2	20	theme	lipid	325:329	arg1	order					339:343	lipid packing order	325:343	lipid packing order	325:343	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	21	theme	compositional	269:281	arg1	differences					392:402	compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences	269:402	compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer	269:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	2	22	theme	H-bonding	368:376	arg1	interactions					378:389	H-bonding interactions	368:389	H-bonding interactions	368:389	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	5	23	theme	collective	1050:1059	arg1	properties					1101:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	3	24	theme	bound	523:527	arg1	molecules					535:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	0	25	theme	lipid	27:31	arg1	symmetry					36:43	lipid (a)symmetry	27:43	lipid (a)symmetry	27:43	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	2	26	theme	acyl	299:302	arg1	group					304:308	lipid head and acyl group	284:308	group	304:308	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	4	27	theme	symmetric	910:918	arg1	arrangements					920:931	symmetric arrangements	910:931	symmetric arrangements	910:931	Although biological membranes are almost universally asymmetric however the asymmetry is not absolute since only drastic difference in the number of lipids per leaflet is found and symmetric arrangements are possible.					
36988943	5	28	theme	biochemical	1061:1071	arg1	properties					1101:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	5	29	theme	core	997:1000	arg1	functions					1013:1021	many core biological functions	992:1021	many core biological functions	992:1021	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	7	30	theme	asymmetric	1333:1342	arg1	state					1344:1348	asymmetric state	1333:1348	asymmetric state	1333:1348	Why cell membranes are (a)symmetric and adopt almost exclusively highly entropically disfavored asymmetric state?					
36988943	2	31	theme	inner	411:415	arg1	leaflets					427:434	the inner and outer leaflets	407:434	the inner and outer leaflets of lipid bilayer	407:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	5	32	theme	biological	1002:1011	arg1	functions					1013:1021	many core biological functions	992:1021	many core biological functions	992:1021	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	0	33	theme	a	34:34	arg1	symmetry					36:43	lipid (a)symmetry	27:43	lipid (a)symmetry	27:43	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	4	34	theme	lipids	878:883	arg1	number					868:873	the number	864:873	the number of lipids per leaflet	864:895	Although biological membranes are almost universally asymmetric however the asymmetry is not absolute since only drastic difference in the number of lipids per leaflet is found and symmetric arrangements are possible.					
36988943	5	35	theme	biophysical	1074:1084	arg1	properties					1101:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	the membrane's collective biochemical, biophysical and structural properties	1035:1110	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	2	36	theme	Membrane	188:195	arg1	asymmetry					197:205	Membrane asymmetry	188:205	Membrane asymmetry	188:205	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	1	37	theme	Membrane	75:82	arg1	means					94:98	Membrane asymmetry means	75:98	Membrane asymmetry means that the two sides of membrane	75:129	Membrane asymmetry means that the two sides of membrane are structurally, physically and functionally different.					
36988943	4	38	from	difference	850:859	arg1	number					868:873	the number	864:873	the number of lipids per leaflet	864:895	Although biological membranes are almost universally asymmetric however the asymmetry is not absolute since only drastic difference in the number of lipids per leaflet is found and symmetric arrangements are possible.					
36988943	7	39	dep	adopt	1277:1281	arg1	disfavored					1322:1331	disfavored	1322:1331	adopt almost exclusively highly entropically disfavored asymmetric state	1277:1348	Why cell membranes are (a)symmetric and adopt almost exclusively highly entropically disfavored asymmetric state?					
36988943	1	40	theme	asymmetry	84:92	arg1	means					94:98	Membrane asymmetry means	75:98	Membrane asymmetry means that the two sides of membrane	75:129	Membrane asymmetry means that the two sides of membrane are structurally, physically and functionally different.					
36988943	6	41	theme	endomembrane	1210:1221	arg1	compartments					1223:1234	all endomembrane compartments	1206:1234	all endomembrane compartments	1206:1234	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	6	42	theme	transbilayer	1124:1135	arg1	distribution					1143:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	3	43	theme	non-covalent	510:521	arg1	molecules					535:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	structurally and conformationally different non-covalent bound lipid molecules	466:543	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	2	44	theme	lipid	233:237	arg1	sidedness					239:247	the lipid sidedness	229:247	the lipid sidedness	229:247	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	3	45	theme	transient	624:632	arg1	arrangements					634:645	transient arrangements	624:645	transient arrangements	624:645	Chemically, structurally and conformationally different non-covalent bound lipid molecules are physically fluid and deformable and enable to interact dynamically to form transient arrangements with asymmetry both perpendicular and parallel to the plane of the lipid bilayer.					
36988943	6	46	theme	Asymmetric	1113:1122	arg1	distribution					1143:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution	1113:1154	Asymmetric transbilayer lipid distribution is found across all lipid classes, cells and near all endomembrane compartments.					
36988943	2	47	theme	lipid	439:443	arg1	bilayer					445:451	lipid bilayer	439:451	lipid bilayer	439:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36988943	0	48	dep	power	4:8	arg1	The					0:2	The	0:2	The	0:2	The power and challenge of lipid (a)symmetry across the membrane and cell.					
36988943	7	49	theme	cell	1241:1244	arg1	membranes					1246:1254	cell membranes	1241:1254	cell membranes	1241:1254	Why cell membranes are (a)symmetric and adopt almost exclusively highly entropically disfavored asymmetric state?					
36988943	5	50	theme	many	992:995	arg1	functions					1013:1021	many core biological functions	992:1021	many core biological functions	992:1021	Asymmetry is thought to direct and influence many core biological functions by altering the membrane's collective biochemical, biophysical and structural properties.					
36988943	2	51	theme	physical	315:322	arg1	differences					392:402	compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences	269:402	compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer	269:451	Membrane asymmetry is largely related to the lipid sidedness and particularly to compositional (lipid head and acyl group) and physical (lipid packing order, charge, hydration and H-bonding interactions) differences in the inner and outer leaflets of lipid bilayer.					
36641188	2	0	from	component	427:435	arg1	foam					451:454	a chitosan foam	440:454	a chitosan foam	440:454	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	3	1	theme	in	505:506	arg1	behavior					523:530	in vitro clotting behavior	505:530	in vitro clotting behavior	505:530	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	4	2	theme	similar	694:700	arg1	clotting					673:680	rapid clotting	667:680	rapid clotting (31 ± 4 s)	667:691	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	4	2	theme	similar	694:700	arg1	31 ± 4 s					683:690	31 ± 4 s	683:690	31 ± 4 s	683:690	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	6	3	theme	clotting	1060:1067	arg1	foam					1011:1014	the designer bilayered foam	988:1014	the designer bilayered foam presented here	988:1029	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	3	theme	clotting	1060:1067	arg1	inducer					1043:1049	a potent inducer	1034:1049	a potent inducer of blood clotting	1034:1067	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	5	4	theme	residue	973:979	arg1	incidences					916:925	markedly higher incidences	900:925	markedly higher incidences of rebleeding (50 %) and left behind material residue	900:979	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	4	5	theme	lower	765:769	arg1	loss					777:780	significantly lower blood loss	751:780	significantly lower blood loss	751:780	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	1	6	theme	approved	115:122	arg1	hemostats					124:132	the approved hemostats	111:132	the approved hemostats for pre-hospital hemorrhagic control	111:169	Chitosan foams are among the approved hemostats for pre-hospital hemorrhagic control but suffer from drawbacks related to mucoadhesiveness and rebleeding.					
36641188	4	7	theme	rat	602:604	arg1	model					606:610	a rat model	600:610	a rat model	600:610	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	5	8	theme	rebleeding	930:939	arg1	incidences					916:925	markedly higher incidences	900:925	markedly higher incidences of rebleeding (50 %) and left behind material residue	900:979	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	3	9	dep	behavior	523:530	arg1	the					501:503	the	501:503	the	501:503	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	3	10	theme	individual	557:566	arg1	components					568:577	individual components	557:577	individual components	557:577	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	2	11	theme	silica	348:353	arg1	≈300 nm					366:372	≈300 nm	366:372	≈300 nm	366:372	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	2	11	theme	silica	348:353	arg1	particles					355:363	silica particles	348:363	silica particles (≈300 nm)	348:373	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	4	12	dep	In	580:581	arg1	vivo					583:586	vivo	583:586	vivo	583:586	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	1	13	theme	Chitosan	86:93	arg1	foams					95:99	Chitosan foams	86:99	Chitosan foams	86:99	Chitosan foams are among the approved hemostats for pre-hospital hemorrhagic control but suffer from drawbacks related to mucoadhesiveness and rebleeding.					
36641188	4	14	from	analysis	588:595	arg1	model					606:610	a rat model	600:610	a rat model	600:610	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	4	15	theme	blood	771:775	arg1	loss					777:780	significantly lower blood loss	751:780	significantly lower blood loss	751:780	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	6	16	theme	blood	1054:1058	arg1	clotting					1060:1067	blood clotting	1054:1067	blood clotting	1054:1067	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	1	17	theme	related	197:203	arg1	drawbacks					187:195	drawbacks	187:195	drawbacks related to mucoadhesiveness and rebleeding	187:238	Chitosan foams are among the approved hemostats for pre-hospital hemorrhagic control but suffer from drawbacks related to mucoadhesiveness and rebleeding.					
36641188	0	18	theme	composite	5:13	arg1	layer					27:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats.					
36641188	3	19	dep	in	505:506	arg1	vitro					508:512	vitro	508:512	vitro	508:512	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	6	20	theme	potent	1036:1041	arg1	foam					1011:1014	the designer bilayered foam	988:1014	the designer bilayered foam presented here	988:1029	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	20	theme	potent	1036:1041	arg1	inducer					1043:1049	a potent inducer	1034:1049	a potent inducer of blood clotting	1034:1067	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	0	21	theme	Silk	0:3	arg1	layer					27:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats.					
36641188	5	22	theme	chitosan	859:866	arg1	foam					868:871	the chitosan foam	855:871	the chitosan foam	855:871	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	2	23	theme	chitosan	442:449	arg1	foam					451:454	a chitosan foam	440:454	a chitosan foam	440:454	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	4	24	contain	had	747:749	arg1	former					740:745	former	740:745	former	740:745	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	4	24	contain	had	747:749	arg2	loss					777:780	significantly lower blood loss	751:780	significantly lower blood loss	751:780	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	3	25	theme	components	568:577	arg1	cytocompatibility					536:552	cytocompatibility	536:552	cytocompatibility	536:552	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	3	25	theme	components	568:577	arg1	behavior					523:530	in vitro clotting behavior	505:530	in vitro clotting behavior	505:530	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	0	26	theme	interfacial	15:25	arg1	layer					27:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer	0:31	Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats.					
36641188	2	27	theme	bioactive	320:328	arg1	layer					330:334	a bioactive layer	318:334	a bioactive layer composed of silica particles (≈300 nm)	318:373	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	4	28	theme	developed	634:642	arg1	hemostat					644:651	the developed hemostat	630:651	the developed hemostat	630:651	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	4	29	theme	In	580:581	arg1	analysis					588:595	In vivo analysis	580:595	In vivo analysis in a rat model	580:610	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	2	30	theme	interfacing	415:425	arg1	component					427:435	the tissue interfacing component	404:435	the tissue interfacing component on a chitosan foam	404:454	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	5	31	theme	bilayered	807:815	arg1	hemostat					817:824	the bilayered hemostat	803:824	the bilayered hemostat	803:824	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	3	32	theme	foam	461:464	arg1	composition					466:476	The foam composition	457:476	The foam composition	457:476	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	0	33	theme	chitosan-based	60:73	arg1	hemostats					75:83	chitosan-based hemostats	60:83	chitosan-based hemostats	60:83	Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats.					
36641188	4	34	theme	chitosan-based	707:720	arg1	hemostat					722:729	a chitosan-based hemostat	705:729	a chitosan-based hemostat	705:729	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	5	35	theme	higher	909:914	arg1	incidences					916:925	markedly higher incidences	900:925	markedly higher incidences of rebleeding (50 %) and left behind material residue	900:979	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	5	36	theme	material	964:971	arg1	residue					973:979	left behind material residue	952:979	left behind material residue	952:979	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	2	37	theme	hemostatic	288:297	arg1	foam					299:302	a designer bilayered hemostatic foam	267:302	a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm)	267:373	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	1	38	theme	pre-hospital	138:149	arg1	control					163:169	pre-hospital hemorrhagic control	138:169	pre-hospital hemorrhagic control	138:169	Chitosan foams are among the approved hemostats for pre-hospital hemorrhagic control but suffer from drawbacks related to mucoadhesiveness and rebleeding.					
36641188	6	39	theme	easy	1086:1089	arg1	removal					1091:1097	easy removal	1086:1097	easy removal with minimal rebleeding	1086:1121	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	40	theme	bilayered	1001:1009	arg1	foam					1011:1014	the designer bilayered foam	988:1014	the designer bilayered foam presented here	988:1029	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	40	theme	bilayered	1001:1009	arg1	inducer					1043:1049	a potent inducer	1034:1049	a potent inducer of blood clotting	1034:1067	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	5	41	theme	behind	957:962	arg1	residue					973:979	left behind material residue	952:979	left behind material residue	952:979	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	2	42	theme	bilayered	278:286	arg1	foam					299:302	a designer bilayered hemostatic foam	267:302	a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm)	267:373	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	1	43	theme	hemorrhagic	151:161	arg1	control					163:169	pre-hospital hemorrhagic control	138:169	pre-hospital hemorrhagic control	138:169	Chitosan foams are among the approved hemostats for pre-hospital hemorrhagic control but suffer from drawbacks related to mucoadhesiveness and rebleeding.					
36641188	6	44	theme	minimal	1104:1110	arg1	rebleeding					1112:1121	minimal rebleeding	1104:1121	minimal rebleeding	1104:1121	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	45	theme	designer	992:999	arg1	foam					1011:1014	the designer bilayered foam	988:1014	the designer bilayered foam presented here	988:1029	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	6	45	theme	designer	992:999	arg1	inducer					1043:1049	a potent inducer	1034:1049	a potent inducer of blood clotting	1034:1067	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	2	46	theme	tissue	408:413	arg1	component					427:435	the tissue interfacing component	404:435	the tissue interfacing component on a chitosan foam	404:454	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	2	47	theme	designer	269:276	arg1	foam					299:302	a designer bilayered hemostatic foam	267:302	a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm)	267:373	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
36641188	3	48	theme	clotting	514:521	arg1	behavior					523:530	in vitro clotting behavior	505:530	in vitro clotting behavior	505:530	The foam composition was optimized based on the in vitro clotting behavior and cytocompatibility of individual components.					
36641188	4	49	theme	rapid	667:671	arg1	clotting					673:680	rapid clotting	667:680	rapid clotting (31 ± 4 s)	667:691	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	4	49	theme	rapid	667:671	arg1	31 ± 4 s					683:690	31 ± 4 s	683:690	31 ± 4 s	683:690	In vivo analysis in a rat model demonstrated that the developed hemostat could achieve rapid clotting (31 ± 4 s), similar to a chitosan-based hemostat, but the former had significantly lower blood loss.					
36641188	6	50	with	removal	1091:1097	arg1	rebleeding					1112:1121	minimal rebleeding	1104:1121	minimal rebleeding	1104:1121	Thus, the designer bilayered foam presented here is a potent inducer of blood clotting whilst affording easy removal with minimal rebleeding.					
36641188	5	51	theme	hemostat	817:824	arg1	removal					792:798	removal	792:798	removal of the bilayered hemostat	792:824	Notably, removal of the bilayered hemostat prevented rebleeding, unlike the chitosan foam, which was associated with markedly higher incidences of rebleeding (50 %) and left behind material residue.					
36641188	0	52	with	rebleeding	44:53	arg1	hemostats					75:83	chitosan-based hemostats	60:83	chitosan-based hemostats	60:83	Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats.					
36641188	2	53	theme	silk	379:382	arg1	fibroin					384:390	silk fibroin	379:390	silk fibroin	379:390	Herein, we have developed a designer bilayered hemostatic foam consisting of a bioactive layer composed of silica particles (≈300 nm) and silk fibroin to serve as the tissue interfacing component on a chitosan foam.					
35438970	0	0	theme	3D	89:90	arg1	Bioprinting					92:102	3D Bioprinting	89:102	3D Bioprinting	89:102	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	7	1	theme	methacrylate	1160:1171	arg1	bioink					1324:1329	the bioink	1320:1329	the bioink for 3D printing afterward	1320:1355	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	7	1	theme	methacrylate	1160:1171	arg1	composition					1128:1138	The composition	1124:1138	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate	1124:1206	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	4	2	theme	protein-polysaccharide	717:738	arg1	hydrogel					753:760	this protein-polysaccharide cross-linked hydrogel	712:760	this protein-polysaccharide cross-linked hydrogel	712:760	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	4	3	theme	Keratin	595:601	arg1	methacrylate					603:614	Keratin methacrylate	595:614	Keratin methacrylate	595:614	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	6	4	theme	degradation	955:965	arg1	properties					943:952	The mechanical properties	928:952	The mechanical properties	928:952	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	4	theme	degradation	955:965	arg1	profile					967:973	degradation profile	955:973	degradation profile	955:973	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	7	5	theme	other	1279:1283	arg1	compositions					1285:1296	other compositions	1279:1296	other compositions	1279:1296	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	8	6	theme	selected	1402:1409	arg1	formula					1411:1417	the selected formula	1398:1417	the selected formula	1398:1417	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	5	7	theme	human	769:773	arg1	keratin					780:786	human hair keratin	769:786	human hair keratin	769:786	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	8	8	theme	stem	1377:1380	arg1	loading					1387:1393	stem cell loading	1377:1393	stem cell loading	1377:1393	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	1	9	dep	three-dimensional	153:169	arg1	3D					172:173	3D	172:173	3D	172:173	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	5	10	theme	hair	775:778	arg1	keratin					780:786	human hair keratin	769:786	human hair keratin	769:786	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	7	11	theme	keratin	1152:1158	arg1	methacrylate					1160:1171	2% (w/v) keratin methacrylate	1143:1171	2% (w/v) keratin methacrylate	1143:1171	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	6	12	theme	mechanical	932:941	arg1	properties					943:952	The mechanical properties	928:952	The mechanical properties	928:952	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	12	theme	mechanical	932:941	arg1	profile					967:973	degradation profile	955:973	degradation profile	955:973	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	12	theme	mechanical	932:941	arg1	behavior					985:992	swelling behavior	976:992	swelling behavior	976:992	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	12	theme	mechanical	932:941	arg1	viability					1000:1008	cell viability	995:1008	cell viability	995:1008	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	12	theme	mechanical	932:941	arg1	proliferation					1015:1027	proliferation	1015:1027	proliferation	1015:1027	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	13	theme	chitosan	1101:1108	arg1	methacrylate					1110:1121	glycol chitosan methacrylate	1094:1121	glycol chitosan methacrylate	1094:1121	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	14	theme	methacrylate	1078:1089	arg1	ratios					1060:1065	various ratios	1052:1065	various ratios of keratin methacrylate to glycol chitosan methacrylate	1052:1121	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	10	15	theme	stem	1689:1692	arg1	hydrogels					1719:1727	stem cell-laden biofabricated hydrogels	1689:1727	stem cell-laden biofabricated hydrogels in the future	1689:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	10	16	theme	biofabricated	1705:1717	arg1	hydrogels					1719:1727	stem cell-laden biofabricated hydrogels	1689:1727	stem cell-laden biofabricated hydrogels in the future	1689:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	7	17	theme	2	1177:1177	arg1	%					1178:1178	%	1178:1178	%	1178:1178	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	10	18	from	research	1677:1684	arg1	hydrogels					1719:1727	stem cell-laden biofabricated hydrogels	1689:1727	stem cell-laden biofabricated hydrogels in the future	1689:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	6	19	theme	various	1052:1058	arg1	ratios					1060:1065	various ratios	1052:1065	various ratios of keratin methacrylate to glycol chitosan methacrylate	1052:1121	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	8	20	from	feasibility	1362:1372	arg1	formula					1411:1417	the selected formula	1398:1417	the selected formula	1398:1417	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	4	21	link	cross-linked	740:751	arg1	hydrogel					753:760	this protein-polysaccharide cross-linked hydrogel	712:760	this protein-polysaccharide cross-linked hydrogel	712:760	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	4	22	theme	hybrid	673:678	arg1	bioink					680:685	a hybrid bioink	671:685	a hybrid bioink	671:685	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	5	23	theme	glycol	847:852	arg1	composition					834:844	the other composition	824:844	the other composition	824:844	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	5	23	theme	glycol	847:852	arg1	chitosan					854:861	glycol chitosan	847:861	glycol chitosan	847:861	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	10	24	from	hydrogels	1719:1727	arg1	future					1736:1741	future	1736:1741	future	1736:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	7	25	theme	2	1143:1143	arg1	%					1144:1144	%	1144:1144	%	1144:1144	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	7	26	theme	swelling	1254:1261	arg1	percentage					1263:1272	swelling percentage	1254:1272	swelling percentage	1254:1272	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	3	27	theme	bioprinting	574:584	arg1	process					586:592	the 3D bioprinting process	567:592	the 3D bioprinting process	567:592	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	7	28	theme	methacrylate	1195:1206	arg1	bioink					1324:1329	the bioink	1320:1329	the bioink for 3D printing afterward	1320:1355	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	7	28	theme	methacrylate	1195:1206	arg1	composition					1128:1138	The composition	1124:1138	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate	1124:1206	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	3	29	theme	available	443:451	arg1	sources					461:467	the readily available biomass sources	431:467	the readily available biomass sources	431:467	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	29	theme	available	443:451	arg1	keratin					470:476	keratin	470:476	keratin	470:476	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	29	theme	available	443:451	arg1	chitosan					489:496	glycol chitosan	482:496	glycol chitosan	482:496	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	1	30	theme	biological	308:317	arg1	tissue					319:324	the biological tissue	304:324	the biological tissue	304:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	7	31	theme	%	1144:1144	arg1	methacrylate					1160:1171	2% (w/v) keratin methacrylate	1143:1171	2% (w/v) keratin methacrylate	1143:1171	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	1	32	from	advancements	114:125	arg1	engineering					137:147	tissue engineering	130:147	tissue engineering	130:147	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	1	32	from	advancements	114:125	arg1	bioprinting					176:186	three-dimensional (3D) bioprinting	153:186	three-dimensional (3D) bioprinting	153:186	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	8	33	theme	loading	1387:1393	arg1	feasibility					1362:1372	The feasibility	1358:1372	The feasibility of stem cell loading in the selected formula	1358:1417	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	3	34	theme	biomass	453:459	arg1	sources					461:467	the readily available biomass sources	431:467	the readily available biomass sources	431:467	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	34	theme	biomass	453:459	arg1	keratin					470:476	keratin	470:476	keratin	470:476	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	34	theme	biomass	453:459	arg1	chitosan					489:496	glycol chitosan	482:496	glycol chitosan	482:496	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	4	35	theme	glycol	620:625	arg1	methacrylate					636:647	glycol chitosan methacrylate	620:647	glycol chitosan methacrylate	620:647	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	1	36	with	structures	232:241	arg1	properties					282:291	suitable mechanical and bioactive properties	248:291	suitable mechanical and bioactive properties that mimic the biological tissue	248:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	3	37	theme	glycol	482:487	arg1	sources					461:467	the readily available biomass sources	431:467	the readily available biomass sources	431:467	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	37	theme	glycol	482:487	arg1	chitosan					489:496	glycol chitosan	482:496	glycol chitosan	482:496	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	7	38	theme	chitosan	1186:1193	arg1	methacrylate					1195:1206	2% (w/v) chitosan methacrylate	1177:1206	2% (w/v) chitosan methacrylate	1177:1206	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	10	39	theme	cell-laden	1694:1703	arg1	hydrogels					1719:1727	stem cell-laden biofabricated hydrogels	1689:1727	stem cell-laden biofabricated hydrogels in the future	1689:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	4	40	theme	chitosan	627:634	arg1	methacrylate					636:647	glycol chitosan methacrylate	620:647	glycol chitosan methacrylate	620:647	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	3	41	theme	3D	571:572	arg1	process					586:592	the 3D bioprinting process	567:592	the 3D bioprinting process	567:592	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	1	42	theme	three-dimensional	214:230	arg1	structures					232:241	physiologically relevant three-dimensional structures	189:241	physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue	189:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	0	43	theme	Cell-Laden	29:38	arg1	Bioinks					77:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	9	44	theme	synthesized	1529:1539	arg1	bioink					1541:1546	the synthesized bioink	1525:1546	the synthesized bioink	1525:1546	The cells and spheroids can be successfully printed with the synthesized bioink into a specific shape and cultured.					
35438970	5	45	theme	construct	917:925	arg1	strength					901:908	the mechanical strength	886:908	the mechanical strength of the construct	886:925	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	6	46	theme	glycol	1094:1099	arg1	methacrylate					1110:1121	glycol chitosan methacrylate	1094:1121	glycol chitosan methacrylate	1094:1121	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	0	47	theme	Stem	24:27	arg1	Bioinks					77:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	6	48	theme	cell	995:998	arg1	properties					943:952	The mechanical properties	928:952	The mechanical properties	928:952	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	48	theme	cell	995:998	arg1	viability					1000:1008	cell viability	995:1008	cell viability	995:1008	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	5	49	theme	other	828:832	arg1	composition					834:844	the other composition	824:844	the other composition	824:844	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	5	49	theme	other	828:832	arg1	chitosan					854:861	glycol chitosan	847:861	glycol chitosan	847:861	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	5	50	theme	mechanical	890:899	arg1	strength					901:908	the mechanical strength	886:908	the mechanical strength of the construct	886:925	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	0	51	theme	Chitosan	55:62	arg1	Bioinks					77:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	7	52	theme	higher	1231:1236	arg1	number					1243:1248	a significantly higher cell number	1215:1248	a significantly higher cell number	1215:1248	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	10	53	theme	potential	1605:1613	arg1	option					1615:1620	a potential option	1603:1620	a potential option for bioinks	1603:1632	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	5	54	theme	biological	802:811	arg1	functions					813:821	biological functions	802:821	biological functions	802:821	While human hair keratin could provide biological functions, the other composition, glycol chitosan, could further enhance the mechanical strength of the construct.					
35438970	2	55	theme	available	371:379	arg1	bioinks					381:387	the available bioinks	367:387	the available bioinks	367:387	However, the available bioinks are less than demanded.					
35438970	0	56	theme	Keratin/Glycol	40:53	arg1	Bioinks					77:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	7	57	dep	%	1178:1178	arg1	w/v					1181:1183	w/v	1181:1183	w/v	1181:1183	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	7	58	theme	cell	1238:1241	arg1	number					1243:1248	a significantly higher cell number	1215:1248	a significantly higher cell number	1215:1248	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	4	59	theme	cross-linked	740:751	arg1	hydrogel					753:760	this protein-polysaccharide cross-linked hydrogel	712:760	this protein-polysaccharide cross-linked hydrogel	712:760	Keratin methacrylate and glycol chitosan methacrylate were synthesized, and a hybrid bioink was created by combining this protein-polysaccharide cross-linked hydrogel.					
35438970	6	60	theme	swelling	976:983	arg1	properties					943:952	The mechanical properties	928:952	The mechanical properties	928:952	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	6	60	theme	swelling	976:983	arg1	behavior					985:992	swelling behavior	976:992	swelling behavior	976:992	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	7	61	theme	%	1178:1178	arg1	methacrylate					1195:1206	2% (w/v) chitosan methacrylate	1177:1206	2% (w/v) chitosan methacrylate	1177:1206	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	6	62	theme	keratin	1070:1076	arg1	methacrylate					1078:1089	keratin methacrylate	1070:1089	keratin methacrylate to glycol chitosan methacrylate	1070:1121	The mechanical properties, degradation profile, swelling behavior, cell viability, and proliferation were investigated with various ratios of keratin methacrylate to glycol chitosan methacrylate.					
35438970	1	63	theme	tissue	130:135	arg1	engineering					137:147	tissue engineering	130:147	tissue engineering	130:147	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	1	64	theme	suitable	248:255	arg1	properties					282:291	suitable mechanical and bioactive properties	248:291	suitable mechanical and bioactive properties that mimic the biological tissue	248:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	8	65	theme	cell	1382:1385	arg1	loading					1387:1393	stem cell loading	1377:1393	stem cell loading	1377:1393	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	7	66	dep	%	1144:1144	arg1	w/v					1147:1149	w/v	1147:1149	w/v	1147:1149	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	8	67	theme	extrusion-based	1440:1454	arg1	bioprinter					1456:1465	an extrusion-based bioprinter	1437:1465	an extrusion-based bioprinter	1437:1465	The feasibility of stem cell loading in the selected formula was examined with an extrusion-based bioprinter.					
35438970	9	68	theme	specific	1555:1562	arg1	shape					1564:1568	a specific shape	1553:1568	a specific shape	1553:1568	The cells and spheroids can be successfully printed with the synthesized bioink into a specific shape and cultured.					
35438970	1	69	theme	mechanical	257:266	arg1	properties					282:291	suitable mechanical and bioactive properties	248:291	suitable mechanical and bioactive properties that mimic the biological tissue	248:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	0	70	theme	Bioinks	77:83	arg1	Synthesis					11:19	Synthesis	11:19	Synthesis	11:19	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	0	70	theme	Bioinks	77:83	arg1	Design					0:5	Design	0:5	Design	0:5	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	1	71	theme	relevant	205:212	arg1	structures					232:241	physiologically relevant three-dimensional structures	189:241	physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue	189:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	3	72	theme	UV-curable	526:535	arg1	feasible					554:561	feasible	554:561	feasible	554:561	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	3	72	theme	UV-curable	526:535	arg1	hydrogel					537:544	a UV-curable hydrogel	524:544	a UV-curable hydrogel that is feasible for the 3D bioprinting process	524:592	In this research, the readily available biomass sources, keratin and glycol chitosan, were selected to develop a UV-curable hydrogel that is feasible for the 3D bioprinting process.					
35438970	7	73	theme	3D	1335:1336	arg1	printing					1338:1345	3D printing afterward	1335:1355	3D printing afterward	1335:1355	The composition of 2% (w/v) keratin methacrylate and 2% (w/v) chitosan methacrylate showed a significantly higher cell number and swelling percentage than other compositions and was designated as the bioink for 3D printing afterward.					
35438970	0	74	theme	Methacrylate	64:75	arg1	Bioinks					77:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks	24:83	Design and Synthesis of Stem Cell-Laden Keratin/Glycol Chitosan Methacrylate Bioinks for 3D Bioprinting.					
35438970	1	75	theme	three-dimensional	153:169	arg1	bioprinting					176:186	three-dimensional (3D) bioprinting	153:186	three-dimensional (3D) bioprinting	153:186	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35438970	10	76	theme	personalization	1661:1675	arg1	research					1677:1684	personalization research	1661:1684	personalization research on stem cell-laden biofabricated hydrogels in the future	1661:1741	This work provides a potential option for bioinks and delivers insights into personalization research on stem cell-laden biofabricated hydrogels in the future.					
35438970	1	77	theme	bioactive	272:280	arg1	properties					282:291	suitable mechanical and bioactive properties	248:291	suitable mechanical and bioactive properties that mimic the biological tissue	248:324	With the advancements in tissue engineering and three-dimensional (3D) bioprinting, physiologically relevant three-dimensional structures with suitable mechanical and bioactive properties that mimic the biological tissue can be designed and fabricated.					
35863235	0	0	theme	ultimate	79:86	arg1	particles					94:102	Towards the ultimate ideal particles	67:102	Towards the ultimate ideal particles for efficient affinity chromatography	67:140	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	5	1	theme	particle	905:912	arg1	properities					876:886	The physical and chemical properities	850:886	The physical and chemical properities of the composite particle	850:912	The physical and chemical properities of the composite particle were thoroughly investigated.					
35863235	4	2	theme	Ni2+	839:842	arg1	ions					844:847	Ni2+ ions	839:847	Ni2+ ions	839:847	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	1	3	theme	affinity	173:180	arg1	particle					190:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	8	4	theme	polymer	1289:1295	arg1	brush					1297:1301	polymer brush	1289:1301	polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials	1289:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	1	5	from	samples	315:321	arg1	purification					245:256	purification	245:256	purification	245:256	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	1	5	from	samples	315:321	arg1	separation					230:239	selective separation	220:239	selective separation	220:239	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	6	6	theme	high	1071:1074	arg1	quantities					1076:1085	high quantities	1071:1085	high quantities of interfering chemicals	1071:1110	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	1	7	theme	agarose	182:188	arg1	particle					190:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	1	8	theme	complicated	292:302	arg1	samples					315:321	complicated biological samples	292:321	complicated biological samples	292:321	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	6	9	from	presence	1059:1066	arg1	separate					1005:1012	separate	1005:1012	separate	1005:1012	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	6	9	from	presence	1059:1066	arg1	experiment					1139:1148	a model protein-binding experiment	1115:1148	a model protein-binding experiment	1115:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	8	10	theme	novel	1533:1537	arg1	materials					1574:1582	novel agarose particles-based functional materials	1533:1582	novel agarose particles-based functional materials	1533:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	3	11	theme	high	605:608	arg1	permeability					610:621	high permeability	605:621	high permeability	605:621	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	3	12	theme	substance	639:647	arg1	tolerance					649:657	interfering substance tolerance	627:657	interfering substance tolerance	627:657	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	1	13	theme	biological	304:313	arg1	samples					315:321	complicated biological samples	292:321	complicated biological samples	292:321	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	0	14	theme	ideal	88:92	arg1	particles					94:102	Towards the ultimate ideal particles	67:102	Towards the ultimate ideal particles for efficient affinity chromatography	67:140	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	2	15	theme	composite	328:336	arg1	particle					338:345	The composite particle	324:345	The composite particle	324:345	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	3	16	theme	Superporous	559:569	arg1	particles					589:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	0	17	theme	efficient	108:116	arg1	chromatography					127:140	efficient affinity chromatography	108:140	efficient affinity chromatography	108:140	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	8	18	theme	target	1361:1366	arg1	proteins					1368:1375	target proteins	1361:1375	target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials	1361:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	2	19	theme	ligand	478:483	arg1	densities					485:493	higher ligand densities	471:493	higher ligand densities	471:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	8	20	theme	particles-based	1547:1561	arg1	materials					1574:1582	novel agarose particles-based functional materials	1533:1582	novel agarose particles-based functional materials	1533:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	21	theme	high	1382:1385	arg1	permeability					1387:1398	high permeability	1382:1398	high permeability	1382:1398	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	22	theme	high	1423:1426	arg1	tolerance					1447:1455	high interfering matrix tolerance	1423:1455	high interfering matrix tolerance	1423:1455	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	23	theme	low	1401:1403	arg1	backpressure					1405:1416	low backpressure	1401:1416	low backpressure	1401:1416	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	24	with	proteins	1368:1375	arg1	permeability					1387:1398	high permeability	1382:1398	high permeability	1382:1398	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	24	with	proteins	1368:1375	arg1	backpressure					1405:1416	low backpressure	1401:1416	low backpressure	1401:1416	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	24	with	proteins	1368:1375	arg1	tolerance					1447:1455	high interfering matrix tolerance	1423:1455	high interfering matrix tolerance	1423:1455	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	3	25	theme	interfering	627:637	arg1	tolerance					649:657	interfering substance tolerance	627:657	interfering substance tolerance	627:657	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	8	26	dep	brush	1297:1301	arg1	enables					1303:1309	enables	1303:1309	enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials	1303:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	4	27	theme	methacrylate	789:800	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	2	28	theme	iminodiacetic	514:526	arg1	brushes					440:446	flexible copolymer brushes	421:446	flexible copolymer brushes as scaffolds to render higher ligand densities	421:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	28	theme	iminodiacetic	514:526	arg1	matrix					413:418	matrix	413:418	matrix	413:418	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	28	theme	iminodiacetic	514:526	arg1	acids					528:532	Ni2+-chelated iminodiacetic acids	500:532	Ni2+-chelated iminodiacetic acids	500:532	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	28	theme	iminodiacetic	514:526	arg1	elements					549:556	recognition elements	537:556	recognition elements	537:556	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	6	29	theme	model	1117:1121	arg1	experiment					1139:1148	a model protein-binding experiment	1115:1148	a model protein-binding experiment	1115:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	2	30	theme	superporous	369:379	arg1	particles					389:397	superporous agarose particles	369:397	superporous agarose particles	369:397	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	8	31	theme	matrix	1440:1445	arg1	tolerance					1447:1455	high interfering matrix tolerance	1423:1455	high interfering matrix tolerance	1423:1455	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	2	32	theme	Ni2+-chelated	500:512	arg1	brushes					440:446	flexible copolymer brushes	421:446	flexible copolymer brushes as scaffolds to render higher ligand densities	421:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	32	theme	Ni2+-chelated	500:512	arg1	matrix					413:418	matrix	413:418	matrix	413:418	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	32	theme	Ni2+-chelated	500:512	arg1	acids					528:532	Ni2+-chelated iminodiacetic acids	500:532	Ni2+-chelated iminodiacetic acids	500:532	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	32	theme	Ni2+-chelated	500:512	arg1	elements					549:556	recognition elements	537:556	recognition elements	537:556	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	6	33	from	separate	1005:1012	arg1	presence					1059:1066	the presence	1055:1066	the presence of high quantities of interfering chemicals in a model protein-binding experiment	1055:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	6	34	theme	histidine-tagged	1014:1029	arg1	proteins					1043:1050	histidine-tagged recombinant proteins	1014:1050	histidine-tagged recombinant proteins	1014:1050	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	0	35	theme	brushes	25:31	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of copolymer brushes	0:31	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	2	36	theme	flexible	421:428	arg1	brushes					440:446	flexible copolymer brushes	421:446	flexible copolymer brushes as scaffolds to render higher ligand densities	421:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	36	theme	flexible	421:428	arg1	acids					528:532	Ni2+-chelated iminodiacetic acids	500:532	Ni2+-chelated iminodiacetic acids	500:532	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	36	theme	flexible	421:428	arg1	matrix					413:418	matrix	413:418	matrix	413:418	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	36	theme	flexible	421:428	arg1	elements					549:556	recognition elements	537:556	recognition elements	537:556	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	8	37	theme	superporous	1249:1259	arg1	particles					1269:1277	The superporous agarose particles	1245:1277	The superporous agarose particles	1245:1277	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	6	38	theme	composite	948:956	arg1	able					985:988	able	985:988	able	985:988	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	6	38	theme	composite	948:956	arg1	particles					958:966	The composite particles	944:966	The composite particles	944:966	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	4	39	theme	N-isopropylacrylamide	754:774	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	0	40	theme	copolymer	15:23	arg1	brushes					25:31	copolymer brushes	15:31	copolymer brushes	15:31	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	6	41	theme	protein-binding	1123:1137	arg1	experiment					1139:1148	a model protein-binding experiment	1115:1148	a model protein-binding experiment	1115:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	0	42	theme	affinity	118:125	arg1	chromatography					127:140	efficient affinity chromatography	108:140	efficient affinity chromatography	108:140	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	6	43	theme	recombinant	1031:1041	arg1	proteins					1043:1050	histidine-tagged recombinant proteins	1014:1050	histidine-tagged recombinant proteins	1014:1050	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	8	44	theme	materials	1574:1582	arg1	fabrication					1518:1528	and fabrication	1514:1528	fabrication	1518:1528	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	6	45	theme	quantities	1076:1085	arg1	presence					1059:1066	the presence	1055:1066	the presence of high quantities of interfering chemicals in a model protein-binding experiment	1055:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	1	46	theme	selective	220:228	arg1	separation					230:239	selective separation	220:239	selective separation	220:239	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	0	47	theme	superporous	41:51	arg1	gels					61:64	superporous agarose gels	41:64	superporous agarose gels	41:64	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	4	48	theme	copolymer	664:672	arg1	brush					674:678	The copolymer brush	660:678	The copolymer brush	660:678	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	4	49	theme	glycidyl	780:787	arg1	methacrylate					789:800	glycidyl methacrylate	780:800	glycidyl methacrylate	780:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	8	50	theme	interfering	1428:1438	arg1	tolerance					1447:1455	high interfering matrix tolerance	1423:1455	high interfering matrix tolerance	1423:1455	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	2	51	theme	higher	471:476	arg1	densities					485:493	higher ligand densities	471:493	higher ligand densities	471:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	52	theme	recognition	537:547	arg1	brushes					440:446	flexible copolymer brushes	421:446	flexible copolymer brushes as scaffolds to render higher ligand densities	421:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	52	theme	recognition	537:547	arg1	acids					528:532	Ni2+-chelated iminodiacetic acids	500:532	Ni2+-chelated iminodiacetic acids	500:532	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	52	theme	recognition	537:547	arg1	matrix					413:418	matrix	413:418	matrix	413:418	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	52	theme	recognition	537:547	arg1	elements					549:556	recognition elements	537:556	recognition elements	537:556	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	5	53	theme	physical	854:861	arg1	properities					876:886	The physical and chemical properities	850:886	The physical and chemical properities of the composite particle	850:912	The physical and chemical properities of the composite particle were thoroughly investigated.					
35863235	5	54	theme	chemical	867:874	arg1	properities					876:886	The physical and chemical properities	850:886	The physical and chemical properities of the composite particle	850:912	The physical and chemical properities of the composite particle were thoroughly investigated.					
35863235	7	55	theme	protein	1184:1190	arg1	binding					1192:1198	the protein binding	1180:1198	the protein binding of the composite particles	1180:1225	By altering the temperature, the protein binding of the composite particles can be modulated.					
35863235	7	56	theme	composite	1207:1215	arg1	particles					1217:1225	the composite particles	1203:1225	the composite particles	1203:1225	By altering the temperature, the protein binding of the composite particles can be modulated.					
35863235	5	57	theme	composite	895:903	arg1	particle					905:912	the composite particle	891:912	the composite particle	891:912	The physical and chemical properities of the composite particle were thoroughly investigated.					
35863235	8	58	theme	functional	1563:1572	arg1	materials					1574:1582	novel agarose particles-based functional materials	1533:1582	novel agarose particles-based functional materials	1533:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	3	59	theme	agarose	571:577	arg1	particles					589:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	0	60	theme	agarose	53:59	arg1	gels					61:64	superporous agarose gels	41:64	superporous agarose gels	41:64	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	6	61	theme	chemicals	1102:1110	arg1	quantities					1076:1085	high quantities	1071:1085	high quantities of interfering chemicals	1071:1110	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	7	62	theme	particles	1217:1225	arg1	binding					1192:1198	the protein binding	1180:1198	the protein binding of the composite particles	1180:1225	By altering the temperature, the protein binding of the composite particles can be modulated.					
35863235	3	63	theme	composite	579:587	arg1	particles					589:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles	559:597	Superporous agarose composite particles endow high permeability and interfering substance tolerance.					
35863235	8	64	theme	efficient	1320:1328	arg1	separation					1330:1339	separation	1330:1339	separation	1330:1339	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	6	65	theme	interfering	1090:1100	arg1	chemicals					1102:1110	interfering chemicals	1090:1110	interfering chemicals	1090:1110	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	1	66	theme	composite	145:153	arg1	particle					190:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	1	67	dep	separation	230:239	arg1	the					216:218	the	216:218	the	216:218	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	4	68	theme	iminodiacetic	815:827	arg1	acids					829:833	iminodiacetic acids	815:833	iminodiacetic acids	815:833	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	4	69	theme	transfer	719:726	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	8	70	theme	agarose	1539:1545	arg1	materials					1574:1582	novel agarose particles-based functional materials	1533:1582	novel agarose particles-based functional materials	1533:1582	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	71	theme	proteins	1368:1375	arg1	purification					1345:1356	purification	1345:1356	purification	1345:1356	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	8	71	theme	proteins	1368:1375	arg1	separation					1330:1339	separation	1330:1339	separation	1330:1339	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	2	72	theme	agarose	381:387	arg1	particles					389:397	superporous agarose particles	369:397	superporous agarose particles	369:397	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	8	73	theme	fast	1311:1314	arg1	separation					1330:1339	separation	1330:1339	separation	1330:1339	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	4	74	theme	atom	714:717	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	0	75	theme	Towards	67:73	arg1	particles					94:102	Towards the ultimate ideal particles	67:102	Towards the ultimate ideal particles for efficient affinity chromatography	67:140	Fabrication of copolymer brushes grafted superporous agarose gels: Towards the ultimate ideal particles for efficient affinity chromatography.					
35863235	2	76	theme	copolymer	430:438	arg1	brushes					440:446	flexible copolymer brushes	421:446	flexible copolymer brushes as scaffolds to render higher ligand densities	421:493	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	76	theme	copolymer	430:438	arg1	acids					528:532	Ni2+-chelated iminodiacetic acids	500:532	Ni2+-chelated iminodiacetic acids	500:532	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	76	theme	copolymer	430:438	arg1	matrix					413:418	matrix	413:418	matrix	413:418	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	2	76	theme	copolymer	430:438	arg1	elements					549:556	recognition elements	537:556	recognition elements	537:556	The composite particle was constructed using superporous agarose particles as supporting matrix, flexible copolymer brushes as scaffolds to render higher ligand densities, and Ni2+-chelated iminodiacetic acids as recognition elements.					
35863235	6	77	attach	presence	1059:1066	arg2	quantities					1076:1085	high quantities	1071:1085	high quantities of interfering chemicals	1071:1110	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	6	77	attach	presence	1059:1066	arg1	experiment					1139:1148	a model protein-binding experiment	1115:1148	a model protein-binding experiment	1115:1148	The composite particles were shown to be able to selectively separate histidine-tagged recombinant proteins in the presence of high quantities of interfering chemicals in a model protein-binding experiment.					
35863235	1	78	theme	histidine-tagged	261:276	arg1	proteins					278:285	histidine-tagged proteins	261:285	histidine-tagged proteins	261:285	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	4	79	theme	surface-initiated	696:712	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	4	80	theme	radical	728:734	arg1	polymerization					736:749	surface-initiated atom transfer radical polymerization	696:749	surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate	696:800	The copolymer brush was prepared by surface-initiated atom transfer radical polymerization of N-isopropylacrylamide and glycidyl methacrylate, followed by iminodiacetic acids and Ni2+ ions.					
35863235	1	81	theme	immobilized-metal	155:171	arg1	particle					190:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle	143:197	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	8	82	theme	agarose	1261:1267	arg1	particles					1269:1277	The superporous agarose particles	1245:1277	The superporous agarose particles	1245:1277	The superporous agarose particles supported polymer brush enables fast and efficient separation and purification of target proteins with high permeability, low backpressure, and high interfering matrix tolerance, which pave the path for bioseparation through designing and fabrication of novel agarose particles-based functional materials.					
35863235	1	83	theme	proteins	278:285	arg1	purification					245:256	purification	245:256	purification	245:256	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35863235	1	83	theme	proteins	278:285	arg1	separation					230:239	selective separation	220:239	selective separation	220:239	A composite immobilized-metal affinity agarose particle was designed for the selective separation and purification of histidine-tagged proteins from complicated biological samples.					
35408663	2	0	theme	films	393:397	arg1	formulations					332:343	five formulations	327:343	five formulations (T1-T5) of biodegradable cassava starch/gelatin films	327:397	This work studied five formulations (T1-T5) of biodegradable cassava starch/gelatin films.					
35408663	2	0	theme	films	393:397	arg1	T1-T5					346:350	T1-T5	346:350	T1-T5	346:350	This work studied five formulations (T1-T5) of biodegradable cassava starch/gelatin films.					
35408663	0	1	theme	Composites	80:89	arg1	Characterization					11:26	Characterization	11:26	Characterization	11:26	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	0	1	theme	Composites	80:89	arg1	Optimization					33:44	Optimization	33:44	Optimization	33:44	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	0	1	theme	Composites	80:89	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	8	2	theme	gelatin	1364:1370	arg1	mass					1372:1375	gelatin mass	1364:1375	gelatin mass rising in the composites	1364:1400	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	9	3	theme	cassava	1475:1481	arg1	starch					1483:1488	the films' cassava starch	1464:1488	the films' cassava starch	1464:1488	On the other hand, opacity did not vary significantly due to the films' cassava starch and gelatin ratio.					
35408663	2	4	theme	starch/gelatin	378:391	arg1	films					393:397	biodegradable cassava starch/gelatin films	356:397	biodegradable cassava starch/gelatin films	356:397	This work studied five formulations (T1-T5) of biodegradable cassava starch/gelatin films.					
35408663	7	5	theme	Increasing	1070:1079	arg1	ratio					1089:1093	Increasing gelatin ratio	1070:1093	Increasing gelatin ratio	1070:1093	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	8	6	theme	vapor	1282:1286	arg1	WVP					1302:1304	WVP	1302:1304	WVP	1302:1304	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	8	6	theme	vapor	1282:1286	arg1	permeability					1288:1299	Water vapor permeability	1276:1299	Water vapor permeability (WVP)	1276:1305	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	10	7	theme	mass	1587:1590	arg1	ratio					1592:1596	a mass ratio	1585:1596	a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging	1585:1692	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	6	8	with	compatibility	921:933	arg1	starch					940:945	starch	940:945	starch	940:945	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	1	9	theme	food	294:297	arg1	industry					299:306	the food industry	290:306	the food industry	290:306	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	0	10	theme	Food-Packaging	95:108	arg1	Applications					110:121	Food-Packaging Applications	95:121	Food-Packaging Applications	95:121	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	7	11	theme	gelatin	1081:1087	arg1	ratio					1089:1093	Increasing gelatin ratio	1070:1093	Increasing gelatin ratio	1070:1093	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	6	12	theme	surface	1050:1056	arg1	morphology					1058:1067	very rough and fractured surface morphology	1025:1067	very rough and fractured surface morphology	1025:1067	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	5	13	theme	electron	853:860	arg1	microscopy					862:871	scanning electron microscopy	844:871	scanning electron microscopy (SEM)	844:877	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	5	13	theme	electron	853:860	arg1	SEM					874:876	SEM	874:876	SEM	874:876	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	2	14	theme	cassava	370:376	arg1	films					393:397	biodegradable cassava starch/gelatin films	356:397	biodegradable cassava starch/gelatin films	356:397	This work studied five formulations (T1-T5) of biodegradable cassava starch/gelatin films.					
35408663	9	15	theme	gelatin	1494:1500	arg1	ratio					1502:1506	gelatin ratio	1494:1506	gelatin ratio	1494:1506	On the other hand, opacity did not vary significantly due to the films' cassava starch and gelatin ratio.					
35408663	7	16	theme	14.6	1228:1231	arg1	±					1233:1233	±	1233:1233	±	1233:1233	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	1	17	theme	environmental	205:217	arg1	pollution					219:227	environmental pollution	205:227	environmental pollution	205:227	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	3	18	theme	FT-IR	475:479	arg1	spectroscopy					481:492	FT-IR spectroscopy	475:492	FT-IR spectroscopy	475:492	The results showed the presence of the starch/gelatin functional groups by FT-IR spectroscopy.					
35408663	6	19	theme	starch/gelatin	960:973	arg1	T4					981:982	T4	981:982	T4	981:982	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	6	19	theme	starch/gelatin	960:973	arg1	film					975:978	the 25/75 starch/gelatin film	950:978	the 25/75 starch/gelatin film (T4)	950:983	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	10	20	from	usefulness	1712:1721	arg1	industry					1745:1752	the food-packaging industry	1726:1752	the food-packaging industry	1726:1752	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	10	21	theme	food-packaging	1730:1743	arg1	industry					1745:1752	the food-packaging industry	1726:1752	the food-packaging industry	1726:1752	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	7	22	theme	±	1145:1145	arg1	%					1150:1150	2.9 ± 0.5%	1141:1150	2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5	1141:1181	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	6	23	theme	fractured	1040:1048	arg1	morphology					1058:1067	very rough and fractured surface morphology	1025:1067	very rough and fractured surface morphology	1025:1067	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	6	24	theme	rough	1030:1034	arg1	morphology					1058:1067	very rough and fractured surface morphology	1025:1067	very rough and fractured surface morphology	1025:1067	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	5	25	theme	homogeneous	796:806	arg1	morphology					816:825	a homogeneous surface morphology	794:825	a homogeneous surface morphology	794:825	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	7	26	theme	±	1168:1168	arg1	%					1174:1174	285.1 ± 10.0%	1162:1174	285.1 ± 10.0% for T5	1162:1181	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	9	27	theme	other	1410:1414	arg1	hand					1416:1419	the other hand	1406:1419	the other hand	1406:1419	On the other hand, opacity did not vary significantly due to the films' cassava starch and gelatin ratio.					
35408663	3	28	theme	groups	465:470	arg1	presence					423:430	the presence	419:430	the presence of the starch/gelatin functional groups	419:470	The results showed the presence of the starch/gelatin functional groups by FT-IR spectroscopy.					
35408663	5	29	theme	surface	808:814	arg1	morphology					816:825	a homogeneous surface morphology	794:825	a homogeneous surface morphology	794:825	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	6	30	theme	25/75	954:958	arg1	T4					981:982	T4	981:982	T4	981:982	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	6	30	theme	25/75	954:958	arg1	film					975:978	the 25/75 starch/gelatin film	950:978	the 25/75 starch/gelatin film (T4)	950:983	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	10	31	theme	appropriate	1642:1652	arg1	ratio					1592:1596	a mass ratio	1585:1596	a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging	1585:1692	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	10	32	theme	53/47	1601:1605	arg1	starch/gelatin					1615:1628	53/47 cassava starch/gelatin	1601:1628	53/47 cassava starch/gelatin	1601:1628	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	4	33	from	°C	688:689	arg1	temperature					662:672	the crystallization temperature	642:672	the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3)	642:773	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	33	from	°C	688:689	arg1	Tc					675:676	Tc	675:676	Tc	675:676	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	34	theme	starch-only	699:709	arg1	T1					717:718	T1	717:718	T1	717:718	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	34	theme	starch-only	699:709	arg1	film					711:714	the starch-only film	695:714	the starch-only film (T1)	695:719	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	35	theme	gelatin	597:603	arg1	amount					587:592	the amount	583:592	the amount of gelatin	583:603	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	35	theme	gelatin	597:603	arg1	gelatin					597:603	gelatin	597:603	gelatin	597:603	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	1	36	from	use	143:145	arg1	packaging					166:174	food packaging	161:174	food packaging	161:174	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	4	37	theme	Differential	495:506	arg1	DSC					530:532	DSC	530:532	DSC	530:532	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	37	theme	Differential	495:506	arg1	calorimetry					517:527	Differential scanning calorimetry	495:527	Differential scanning calorimetry (DSC)	495:533	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	38	theme	50/50	749:753	arg1	T3					771:772	T3	771:772	T3	771:772	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	38	theme	50/50	749:753	arg1	starch/gelatin					755:768	50/50 starch/gelatin	749:768	50/50 starch/gelatin (T3)	749:773	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	10	39	from	application	1664:1674	arg1	packaging					1684:1692	food packaging	1679:1692	food packaging	1679:1692	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	6	40	theme	Tc	1007:1008	arg1	definition					1010:1019	the low Tc definition	999:1019	the low Tc definition	999:1019	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	3	41	theme	starch/gelatin	439:452	arg1	groups					465:470	the starch/gelatin functional groups	435:470	the starch/gelatin functional groups	435:470	The results showed the presence of the starch/gelatin functional groups by FT-IR spectroscopy.					
35408663	7	42	theme	tensile	1205:1211	arg1	strength					1213:1220	the tensile strength	1201:1220	the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5)	1201:1273	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	7	43	from	%	1150:1150	arg1	strain					1128:1133	the strain	1124:1133	the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5)	1124:1182	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	10	44	theme	starch/gelatin	1615:1628	arg1	ratio					1592:1596	a mass ratio	1585:1596	a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging	1585:1692	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	7	45	theme	0.5	1235:1237	arg1	±					1233:1233	±	1233:1233	±	1233:1233	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	6	46	theme	low	1003:1005	arg1	definition					1010:1019	the low Tc definition	999:1019	the low Tc definition	999:1019	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	3	47	theme	functional	454:463	arg1	groups					465:470	the starch/gelatin functional groups	435:470	the starch/gelatin functional groups	435:470	The results showed the presence of the starch/gelatin functional groups by FT-IR spectroscopy.					
35408663	8	48	theme	water	1322:1326	arg1	WS					1340:1341	WS	1340:1341	WS	1340:1341	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	8	48	theme	water	1322:1326	arg1	solubility					1328:1337	water solubility	1322:1337	water solubility (WS)	1322:1342	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	10	49	theme	cassava	1607:1613	arg1	starch/gelatin					1615:1628	53/47 cassava starch/gelatin	1601:1628	53/47 cassava starch/gelatin	1601:1628	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	5	50	theme	scanning	844:851	arg1	microscopy					862:871	scanning electron microscopy	844:871	scanning electron microscopy (SEM)	844:877	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	5	50	theme	scanning	844:851	arg1	SEM					874:876	SEM	874:876	SEM	874:876	It also exhibited a homogeneous surface morphology, as evidenced by scanning electron microscopy (SEM).					
35408663	4	51	theme	scanning	508:515	arg1	DSC					530:532	DSC	530:532	DSC	530:532	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	51	theme	scanning	508:515	arg1	calorimetry					517:527	Differential scanning calorimetry	495:527	Differential scanning calorimetry (DSC)	495:533	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	7	52	theme	0.3	1259:1261	arg1	±					1257:1257	±	1257:1257	±	1257:1257	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	1	53	theme	indiscriminate	128:141	arg1	use					143:145	The indiscriminate use	124:145	The indiscriminate use of plastic in food packaging	124:174	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	10	54	theme	barrier	1554:1560	arg1	properties					1562:1571	the mechanical and water barrier properties	1529:1571	properties	1562:1571	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	6	55	theme	low	917:919	arg1	compatibility					921:933	low compatibility	917:933	low compatibility with starch	917:945	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	6	56	theme	gelatin	902:908	arg1	excess					892:897	an excess	889:897	an excess of gelatin	889:908	However, an excess of gelatin showed low compatibility with starch in the 25/75 starch/gelatin film (T4), evidenced by the low Tc definition and very rough and fractured surface morphology.					
35408663	8	57	theme	Water	1276:1280	arg1	WVP					1302:1304	WVP	1302:1304	WVP	1302:1304	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	8	57	theme	Water	1276:1280	arg1	permeability					1288:1299	Water vapor permeability	1276:1299	Water vapor permeability (WVP)	1276:1305	Water vapor permeability (WVP) increased, and water solubility (WS) also decreased with gelatin mass rising in the composites.					
35408663	2	58	theme	biodegradable	356:368	arg1	films					393:397	biodegradable cassava starch/gelatin films	356:397	biodegradable cassava starch/gelatin films	356:397	This work studied five formulations (T1-T5) of biodegradable cassava starch/gelatin films.					
35408663	4	59	with	film	739:742	arg1	T3					771:772	T3	771:772	T3	771:772	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	59	with	film	739:742	arg1	starch/gelatin					755:768	50/50 starch/gelatin	749:768	50/50 starch/gelatin (T3)	749:773	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	7	60	dep	strength	1213:1220	arg1	MPa					1239:1241	from 14.6 ± 0.5 MPa	1223:1241	from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5	1223:1272	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	7	61	theme	1.5	1253:1255	arg1	±					1257:1257	±	1257:1257	±	1257:1257	Increasing gelatin ratio also significantly increased the strain (from 2.9 ± 0.5% for T1 to 285.1 ± 10.0% for T5) while decreasing the tensile strength (from 14.6 ± 0.5 MPa for T1 to 1.5 ± 0.3 MPa for T5).					
35408663	1	62	theme	plastic	150:156	arg1	use					143:145	The indiscriminate use	124:145	The indiscriminate use of plastic in food packaging	124:174	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	4	63	theme	crystallization	646:660	arg1	temperature					662:672	the crystallization temperature	642:672	the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3)	642:773	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	4	63	theme	crystallization	646:660	arg1	Tc					675:676	Tc	675:676	Tc	675:676	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	0	64	theme	Gelatin	72:78	arg1	Composites					80:89	Starch/Chicken Gelatin Composites	57:89	Starch/Chicken Gelatin Composites	57:89	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	10	65	theme	food	1679:1682	arg1	packaging					1684:1692	food packaging	1679:1692	food packaging	1679:1692	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	10	66	theme	water	1548:1552	arg1	properties					1562:1571	the mechanical and water barrier properties	1529:1571	properties	1562:1571	Finally, optimizing the mechanical and water barrier properties resulted in a mass ratio of 53/47 cassava starch/gelatin as the most appropriate for their application in food packaging, indicating their usefulness in the food-packaging industry.					
35408663	1	67	theme	eco-friendly	260:271	arg1	alternatives					273:284	more eco-friendly alternatives	255:284	more eco-friendly alternatives	255:284	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35408663	0	68	theme	Starch/Chicken	57:70	arg1	Composites					80:89	Starch/Chicken Gelatin Composites	57:89	Starch/Chicken Gelatin Composites	57:89	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	4	69	theme	thermal	544:550	arg1	reinforcement					552:564	a thermal reinforcement	542:564	a thermal reinforcement	542:564	Differential scanning calorimetry (DSC) showed a thermal reinforcement after increasing the amount of gelatin in the formulations, which increased the crystallization temperature (Tc) from 190 °C for the starch-only film (T1) to 206 °C for the film with 50/50 starch/gelatin (T3).					
35408663	0	70	dep	Synthesis	0:8	arg1	Studies					46:52	Studies	46:52	Studies	46:52	Synthesis, Characterization, and Optimization Studies of Starch/Chicken Gelatin Composites for Food-Packaging Applications.					
35408663	1	71	theme	food	161:164	arg1	packaging					166:174	food packaging	161:174	food packaging	161:174	The indiscriminate use of plastic in food packaging contributes significantly to environmental pollution, promoting the search for more eco-friendly alternatives for the food industry.					
35182566	5	0	theme	rheological	743:753	arg1	features					789:796	rheological, compositional, and morphological features	743:796	rheological, compositional, and morphological features	743:796	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	1	1	from	knowledge	160:168	arg1	properties					177:186	the properties	173:186	the properties of different types of cellulose nanofibers (CNFs)	173:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	2	2	theme	treatments	342:351	arg1	effectiveness					321:333	effectiveness	321:333	effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils	321:528	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	5	3	theme	critical	720:727	arg1	comparison					729:738	a critical comparison	718:738	a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants	718:865	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	4	theme	enzymatic	957:965	arg1	ones					992:995	enzymatic, chemical and mechanical ones	957:995	enzymatic, chemical and mechanical ones	957:995	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	6	5	from	parameters	1267:1276	arg1	case					1286:1289	each case	1281:1289	each case	1281:1289	This structured information will be exceedingly useful to select the most appropriate CNF for a certain application based on the most relevant parameters in each case.					
35182566	5	6	theme	microscopic	1100:1110	arg1	parameters					1112:1121	macroscopic and microscopic parameters	1084:1121	macroscopic and microscopic parameters	1084:1121	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	7	theme	pretreatments	932:944	arg1	types					907:911	different types	897:911	different types	897:911	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	7	theme	pretreatments	932:944	arg1	intensities					917:927	intensities	917:927	intensities	917:927	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	8	theme	chemical	968:975	arg1	ones					992:995	enzymatic, chemical and mechanical ones	957:995	enzymatic, chemical and mechanical ones	957:995	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	9	theme	woody	854:858	arg1	plants					860:865	woody plants	854:865	woody plants	854:865	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	0	10	theme	enzymatic	106:114	arg1	processes					141:149	enzymatic, chemical and mechanical processes	106:149	enzymatic, chemical and mechanical processes	106:149	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	0	11	theme	Critical	0:7	arg1	comparison					9:18	Critical comparison	0:18	Critical comparison of the properties of cellulose	0:49	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	5	12	theme	plants	860:865	arg1	types					845:849	the most representative types	821:849	the most representative types of woody plants	821:865	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	4	13	theme	extensive	655:663	arg1	guide					665:669	an extensive guide	652:669	an extensive guide to compare the CNFs	652:689	However, there is a lack of an extensive guide to compare the CNFs.					
35182566	6	14	theme	relevant	1258:1265	arg1	parameters					1267:1276	the most relevant parameters	1249:1276	the most relevant parameters in each case	1249:1289	This structured information will be exceedingly useful to select the most appropriate CNF for a certain application based on the most relevant parameters in each case.					
35182566	2	15	theme	cellulose	449:457	arg1	fibrillation					459:470	cellulose fibrillation and final mechanical process	449:499	fibrillation	459:470	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	2	16	theme	raw	306:308	arg1	materials					310:318	raw materials	306:318	raw materials	306:318	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	0	17	theme	cellulose	41:49	arg1	properties					27:36	the properties	23:36	the properties of cellulose	23:49	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	2	18	theme	cellulose	368:376	arg1	fraction					378:385	the cellulose fraction	364:385	the cellulose fraction	364:385	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	1	19	theme	types	201:205	arg1	properties					177:186	the properties	173:186	the properties of different types of cellulose nanofibers (CNFs)	173:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	3	20	theme	different	606:614	arg1	routes					616:621	different routes	606:621	different routes	606:621	Literature offers multiple parameters to characterize the CNFs prepared by different routes.					
35182566	0	21	theme	chemical	117:124	arg1	processes					141:149	enzymatic, chemical and mechanical processes	106:149	enzymatic, chemical and mechanical processes	106:149	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	6	22	theme	appropriate	1198:1208	arg1	CNF					1210:1212	the most appropriate CNF	1189:1212	the most appropriate CNF for a certain application based on the most relevant parameters in each case	1189:1289	This structured information will be exceedingly useful to select the most appropriate CNF for a certain application based on the most relevant parameters in each case.					
35182566	2	23	dep	extensive	282:290	arg1	effectiveness					321:333	effectiveness	321:333	effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils	321:528	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	5	24	theme	representative	830:843	arg1	types					845:849	the most representative types	821:849	the most representative types of woody plants	821:865	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	25	theme	morphological	775:787	arg1	features					789:796	rheological, compositional, and morphological features	743:796	rheological, compositional, and morphological features	743:796	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	4	26	theme	guide	665:669	arg1	lack					644:647	a lack	642:647	a lack of an extensive guide to compare the CNFs	642:689	However, there is a lack of an extensive guide to compare the CNFs.					
35182566	0	27	dep	nanofibers	51:60	arg1	produced					62:69	produced	62:69	nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes	51:149	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	1	28	theme	different	191:199	arg1	types					201:205	different types	191:205	different types of cellulose nanofibers (CNFs)	191:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	1	29	theme	cellulose	210:218	arg1	CNFs					232:235	CNFs	232:235	CNFs	232:235	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	1	29	theme	cellulose	210:218	arg1	nanofibers					220:229	cellulose nanofibers	210:229	cellulose nanofibers (CNFs)	210:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	2	30	theme	mechanical	482:491	arg1	process					493:499	cellulose fibrillation and final mechanical process	449:499	process	493:499	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	0	31	theme	properties	27:36	arg1	comparison					9:18	Critical comparison	0:18	Critical comparison of the properties of cellulose	0:49	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	2	32	theme	lignocellulosic	396:410	arg1	biomass					412:418	the lignocellulosic biomass	392:418	the lignocellulosic biomass	392:418	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	2	33	theme	final	476:480	arg1	process					493:499	cellulose fibrillation and final mechanical process	449:499	process	493:499	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	5	34	theme	CNFs	801:804	arg1	features					789:796	rheological, compositional, and morphological features	743:796	rheological, compositional, and morphological features	743:796	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	35	theme	macroscopic	1084:1094	arg1	parameters					1112:1121	macroscopic and microscopic parameters	1084:1121	macroscopic and microscopic parameters	1084:1121	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	36	theme	different	897:905	arg1	types					907:911	different types	897:911	different types	897:911	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	0	37	theme	mechanical	130:139	arg1	processes					141:149	enzymatic, chemical and mechanical processes	106:149	enzymatic, chemical and mechanical processes	106:149	Critical comparison of the properties of cellulose nanofibers produced from softwood and hardwood through enzymatic, chemical and mechanical processes.					
35182566	5	38	theme	mechanical	1026:1035	arg1	treatment					1037:1045	mechanical treatment	1026:1045	mechanical treatment focusing on the relationship between macroscopic and microscopic parameters	1026:1121	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	39	theme	treatment	1037:1045	arg1	severity					1014:1021	the severity	1010:1021	the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters	1010:1121	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	40	theme	mechanical	981:990	arg1	ones					992:995	enzymatic, chemical and mechanical ones	957:995	enzymatic, chemical and mechanical ones	957:995	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	6	41	theme	structured	1129:1138	arg1	information					1140:1150	This structured information	1124:1150	This structured information	1124:1150	This structured information will be exceedingly useful to select the most appropriate CNF for a certain application based on the most relevant parameters in each case.					
35182566	6	42	theme	certain	1220:1226	arg1	application					1228:1238	a certain application	1218:1238	a certain application based on the most relevant parameters in each case	1218:1289	This structured information will be exceedingly useful to select the most appropriate CNF for a certain application based on the most relevant parameters in each case.					
35182566	2	43	theme	Properties	253:262	arg1	variation					264:272	Properties variation	253:272	Properties variation	253:272	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	2	44	from	biomass	412:418	arg1	extract					356:362	extract	356:362	extract	356:362	Properties variation is very extensive, depending on raw materials, effectiveness of the treatments to extract the cellulose fraction from the lignocellulosic biomass, pretreatments to facilitate cellulose fibrillation and final mechanical process to separate the microfibrils.					
35182566	3	45	theme	multiple	549:556	arg1	parameters					558:567	multiple parameters	549:567	multiple parameters	549:567	Literature offers multiple parameters to characterize the CNFs prepared by different routes.					
35182566	5	46	dep	perform	710:716	arg1	using					891:895	using	891:895	using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones	891:995	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	46	dep	perform	710:716	arg1	varying					1002:1008	varying	1002:1008	varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters	1002:1121	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	1	47	theme	nanofibers	220:229	arg1	types					201:205	different types	191:205	different types of cellulose nanofibers (CNFs)	191:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35182566	5	48	theme	compositional	756:768	arg1	features					789:796	rheological, compositional, and morphological features	743:796	rheological, compositional, and morphological features	743:796	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	49	theme	features	789:796	arg1	softwood					881:888	softwood	881:888	softwood	881:888	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	49	theme	features	789:796	arg1	comparison					729:738	a critical comparison	718:738	a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants	718:865	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	5	49	theme	features	789:796	arg1	hardwood					868:875	hardwood	868:875	hardwood	868:875	In this study, we perform a critical comparison of rheological, compositional, and morphological features of CNFs, produced from the most representative types of woody plants, hardwood and softwood, using different types and intensities of pretreatments, including enzymatic, chemical and mechanical ones, and varying the severity of mechanical treatment focusing on the relationship between macroscopic and microscopic parameters.					
35182566	1	50	theme	Current	152:158	arg1	knowledge					160:168	Current knowledge	152:168	Current knowledge on the properties of different types of cellulose nanofibers (CNFs)	152:236	Current knowledge on the properties of different types of cellulose nanofibers (CNFs) is fragmented.					
35422287	0	0	theme	wound	106:110	arg1	healing					112:118	guided wound healing	99:118	guided wound healing	99:118	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
35422287	2	1	theme	ASF	532:534	arg1	scaffold					536:543	the ASF scaffold	528:543	the ASF scaffold	528:543	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	2	2	from	effect	410:415	arg1	concentrations					446:459	three different concentrations	430:459	three different concentrations of CNCs (0.5%, 1%, and 2%)	430:486	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	0	3	theme	guided	99:104	arg1	healing					112:118	guided wound healing	99:118	guided wound healing	99:118	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
35422287	5	4	theme	in	1041:1042	arg1	conditions					1049:1058	in vivo conditions	1041:1058	in vivo conditions	1041:1058	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	4	5	theme	modulus	788:794	arg1	control					806:812	Young's modulus vis-à-vis control	780:812	Young's modulus vis-à-vis control	780:812	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	1	6	theme	cellulose	187:195	arg1	CNCs					211:214	CNCs	211:214	CNCs	211:214	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	6	theme	cellulose	187:195	arg1	nanocrystals					197:208	cellulose nanocrystals	187:208	cellulose nanocrystals (CNCs)	187:215	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	7	theme	vis-à-vis	796:804	arg1	control					806:812	Young's modulus vis-à-vis control	780:812	Young's modulus vis-à-vis control	780:812	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	5	8	theme	aligned	941:947	arg1	scaffolds					949:957	the magnetically aligned scaffolds	924:957	the magnetically aligned scaffolds	924:957	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	2	9	dep	CNCs	464:467	arg1	%					473:473	0.5%	470:473	0.5%	470:473	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	2	9	dep	CNCs	464:467	arg1	%					477:477	1%	476:477	1%	476:477	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	2	9	dep	CNCs	464:467	arg1	%					485:485	2%	484:485	2%	484:485	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	6	10	theme	anisotropic	1140:1150	arg1	constructs					1152:1161	biomimetic anisotropic constructs	1129:1161	biomimetic anisotropic constructs for wound healing applications	1129:1192	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	5	11	theme	endothelial	894:904	arg1	cells					906:910	endothelial cells	894:910	endothelial cells	894:910	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	1	12	theme	low-strength	266:277	arg1	MF					304:305	MF	304:305	MF	304:305	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	12	theme	low-strength	266:277	arg1	field					297:301	a low-strength (0.28 T) magnetic field	264:301	a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	264:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	13	theme	aligned	342:348	arg1	scaffold					396:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	14	theme	control	806:812	arg1	enhancement					765:775	significant enhancement	753:775	significant enhancement of Young's modulus vis-à-vis control	753:812	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	6	15	theme	wound	1167:1171	arg1	healing					1173:1179	wound healing	1167:1179	wound healing applications	1167:1192	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	6	16	theme	biomimetic	1129:1138	arg1	constructs					1152:1161	biomimetic anisotropic constructs	1129:1161	biomimetic anisotropic constructs for wound healing applications	1129:1192	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	1	17	from	magneto-responsiveness	161:182	arg1	matrix					251:256	an alginate-silk fibroin (ASF) matrix	220:256	an alginate-silk fibroin (ASF) matrix	220:256	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	18	theme	nanocrystals	197:208	arg1	magneto-responsiveness					161:182	the magneto-responsiveness	157:182	the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix	157:256	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	19	theme	higher	692:697	arg1	degree					699:704	a higher degree	690:704	a higher degree of anisotropy of the MF-treated scaffolds	690:746	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	0	20	theme	field-assisted	9:22	arg1	patterning					32:41	Magnetic field-assisted aligned patterning	0:41	Magnetic field-assisted aligned patterning in an alginate-silk	0:61	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
35422287	0	21	theme	Magnetic	0:7	arg1	patterning					32:41	Magnetic field-assisted aligned patterning	0:41	Magnetic field-assisted aligned patterning in an alginate-silk	0:61	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
35422287	2	22	theme	scaffold	536:543	arg1	alignment					515:523	the alignment	511:523	the alignment of the ASF scaffold	511:543	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	4	23	dep	AFM	656:658	arg1	SEM					651:653	The SEM	647:653	The SEM	647:653	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	3	24	theme	concentration-dependent	586:608	arg1	anisotropy					610:619	a concentration-dependent anisotropy	584:619	a concentration-dependent anisotropy	584:619	The as-fabricated scaffolds exhibited a concentration-dependent anisotropy with respect to the CNCs.					
35422287	2	25	theme	MF	424:425	arg1	effect					410:415	The effect	406:415	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%)	406:486	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	6	26	theme	CNCs	1093:1096	arg1	useful					1107:1112	useful	1107:1112	useful	1107:1112	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	6	26	theme	CNCs	1093:1096	arg1	property					1081:1088	the magnetic property	1068:1088	the magnetic property of CNCs	1068:1096	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	5	27	theme	enhanced	966:973	arg1	proliferation					975:987	enhanced proliferation	966:987	enhanced proliferation	966:987	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	0	28	theme	aligned	24:30	arg1	patterning					32:41	Magnetic field-assisted aligned patterning	0:41	Magnetic field-assisted aligned patterning in an alginate-silk	0:61	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
35422287	1	29	theme	magnetic	288:295	arg1	MF					304:305	MF	304:305	MF	304:305	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	29	theme	magnetic	288:295	arg1	field					297:301	a low-strength (0.28 T) magnetic field	264:301	a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	264:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	30	theme	SAXS	666:669	arg1	analysis					671:678	SAXS analysis	666:678	SAXS analysis	666:678	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	2	31	theme	CNCs	464:467	arg1	concentrations					446:459	three different concentrations	430:459	three different concentrations of CNCs (0.5%, 1%, and 2%)	430:486	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	1	32	theme	wound	382:386	arg1	scaffold					396:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	33	theme	scaffolds	738:746	arg1	degree					699:704	a higher degree	690:704	a higher degree of anisotropy of the MF-treated scaffolds	690:746	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	1	34	theme	alginate-silk	223:235	arg1	matrix					251:256	an alginate-silk fibroin (ASF) matrix	220:256	an alginate-silk fibroin (ASF) matrix	220:256	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	35	theme	healing	388:394	arg1	scaffold					396:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	327:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	36	theme	MF-treated	727:736	arg1	scaffolds					738:746	the MF-treated scaffolds	723:746	the MF-treated scaffolds	723:746	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	1	37	theme	fibroin	237:243	arg1	matrix					251:256	an alginate-silk fibroin (ASF) matrix	220:256	an alginate-silk fibroin (ASF) matrix	220:256	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	38	theme	scaffold	396:403	arg1	fabrication					312:322	fabrication	312:322	fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold	312:403	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	4	39	theme	significant	753:763	arg1	enhancement					765:775	significant enhancement	753:775	significant enhancement of Young's modulus vis-à-vis control	753:812	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	2	40	theme	different	436:444	arg1	concentrations					446:459	three different concentrations	430:459	three different concentrations of CNCs (0.5%, 1%, and 2%)	430:486	The effect of the MF on three different concentrations of CNCs (0.5%, 1%, and 2%) was studied to control the alignment of the ASF scaffold.					
35422287	1	41	dep	aligned	342:348	arg1	three-dimensional					364:380	three-dimensional	364:380	three-dimensional	364:380	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	1	41	dep	aligned	342:348	arg1	anisotropic					351:361	anisotropic	351:361	anisotropic	351:361	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	5	42	theme	Skin	857:860	arg1	fibroblasts					862:872	Skin fibroblasts	857:872	Skin fibroblasts	857:872	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	6	43	theme	healing	1173:1179	arg1	applications					1181:1192	wound healing applications	1167:1192	wound healing applications	1167:1192	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	4	44	theme	anisotropy	709:718	arg1	degree					699:704	a higher degree	690:704	a higher degree of anisotropy of the MF-treated scaffolds	690:746	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	6	45	theme	magnetic	1072:1079	arg1	useful					1107:1112	useful	1107:1112	useful	1107:1112	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	6	45	theme	magnetic	1072:1079	arg1	property					1081:1088	the magnetic property	1068:1088	the magnetic property of CNCs	1068:1096	Hence, the magnetic property of CNCs could be useful for developing biomimetic anisotropic constructs for wound healing applications.					
35422287	5	46	dep	in	1041:1042	arg1	vivo					1044:1047	vivo	1044:1047	vivo	1044:1047	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	4	47	theme	mechanical	835:844	arg1	stability					846:854	their mechanical stability	829:854	their mechanical stability	829:854	The SEM, AFM, and, SAXS analysis indicated a higher degree of anisotropy of the MF-treated scaffolds with significant enhancement of Young's modulus vis-à-vis control, demonstrating their mechanical stability.					
35422287	5	48	theme	rapid	1015:1019	arg1	closure					1027:1033	rapid wound closure	1015:1033	rapid wound closure	1015:1033	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	3	49	theme	as-fabricated	550:562	arg1	scaffolds					564:572	The as-fabricated scaffolds	546:572	The as-fabricated scaffolds	546:572	The as-fabricated scaffolds exhibited a concentration-dependent anisotropy with respect to the CNCs.					
35422287	1	50	theme	ASF	246:248	arg1	matrix					251:256	an alginate-silk fibroin (ASF) matrix	220:256	an alginate-silk fibroin (ASF) matrix	220:256	This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals (CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field (MF) for fabrication of a magnetically aligned, anisotropic, three-dimensional wound healing scaffold.					
35422287	5	51	theme	wound	1021:1025	arg1	closure					1027:1033	rapid wound closure	1015:1033	rapid wound closure	1015:1033	Skin fibroblasts, keratinocytes, and endothelial cells cultured on the magnetically aligned scaffolds showed enhanced proliferation in vitro and demonstrated rapid wound closure under in vivo conditions.					
35422287	0	52	from	patterning	32:41	arg1	alginate-silk					49:61	an alginate-silk	46:61	an alginate-silk	46:61	Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing.					
36889472	4	0	theme	humidity	857:864	arg1	impact					847:852	the non-negligible impact	828:852	the non-negligible impact of humidity on the sensitivity	828:883	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	3	1	dep	oxide	523:527	arg1	[X = Cel					560:567	ZnO/X [X = Cel	554:567	ZnO/X [X = Cel	554:567	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	5	2	theme	products	1085:1092	arg1	structures					1042:1051	geometrical/electronic structures	1019:1051	geometrical/electronic structures	1019:1051	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	5	2	theme	products	1085:1092	arg1	thermodynamics					1000:1013	the calculated thermodynamics	985:1013	the calculated thermodynamics	985:1013	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	5	3	theme	calculated	989:998	arg1	thermodynamics					1000:1013	the calculated thermodynamics	985:1013	the calculated thermodynamics	985:1013	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	4	4	theme	nitrate	750:756	arg1	intermediates					758:770	nitrate intermediates	750:770	nitrate intermediates	750:770	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	2	5	theme	gas	318:320	arg1	sensors					322:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	0	6	theme	oxide-based	83:93	arg1	sensors					95:101	zinc oxide-based sensors	78:101	zinc oxide-based sensors	78:101	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	3	7	theme	materials	497:505	arg1	series					477:482	a series	475:482	a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)]	475:611	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	0	8	theme	zinc	78:81	arg1	sensors					95:101	zinc oxide-based sensors	78:101	zinc oxide-based sensors	78:101	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	7	9	theme	NO2	1326:1328	arg1	sensing					1330:1336	unearth novel NO2 sensing	1312:1336	unearth novel NO2 sensing	1312:1336	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	2	10	theme	involved	406:413	arg1	intermediates					415:427	involved intermediates	406:427	involved intermediates	406:427	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	7	11	theme	unearth	1312:1318	arg1	sensing					1330:1336	unearth novel NO2 sensing	1312:1336	unearth novel NO2 sensing	1312:1336	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	3	12	theme	sensitive	487:495	arg1	materials					497:505	sensitive materials	487:505	sensitive materials	487:505	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	12	theme	sensitive	487:495	arg1	Gr					598:599	Gr	598:599	Gr (graphene)]	598:611	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	12	theme	sensitive	487:495	arg1	CN					582:583	CN	582:583	CN (g-C3N4)	582:592	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	12	theme	sensitive	487:495	arg1	oxide					523:527	zinc oxide	518:527	zinc oxide (ZnO)	518:533	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	12	theme	sensitive	487:495	arg1	composites					543:552	its composites	539:552	its composites	539:552	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	2	13	theme	NO2	350:352	arg1	gas					354:356	NO2 gas	350:356	NO2 gas	350:356	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	7	14	theme	novel	1320:1324	arg1	sensing					1330:1336	unearth novel NO2 sensing	1312:1336	unearth novel NO2 sensing	1312:1336	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	5	15	theme	reactants	1056:1064	arg1	structures					1042:1051	geometrical/electronic structures	1019:1051	geometrical/electronic structures	1019:1051	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	5	15	theme	reactants	1056:1064	arg1	thermodynamics					1000:1013	the calculated thermodynamics	985:1013	the calculated thermodynamics	985:1013	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	3	16	theme	density	651:657	arg1	theory					670:675	density functional theory	651:675	density functional theory	651:675	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	2	17	dep	mechanism	392:400	arg1	structures					429:438	structures	429:438	structures	429:438	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	2	18	theme	sensing	384:390	arg1	mechanism					392:400	the sensing mechanism	380:400	the sensing mechanism	380:400	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	3	19	theme	functional	659:668	arg1	theory					670:675	density functional theory	651:675	density functional theory	651:675	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	0	20	theme	enhanced	113:120	arg1	activity					122:129	their enhanced activity	107:129	their enhanced activity towards air pollutant nitrogen dioxide	107:168	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	6	21	dep	complexes	1186:1194	arg1	complexes					1186:1194	their complexes	1180:1194	composites (ZnO/X) as well as their complexes (ZnO- and ZnO/X-adsorbates)	1150:1222	The interfacial interaction has been elaborated on for composites (ZnO/X) as well as their complexes (ZnO- and ZnO/X-adsorbates).					
36889472	6	21	dep	complexes	1186:1194	arg1	ZnO/X-adsorbates					1206:1221	ZnO/X-adsorbates	1206:1221	ZnO/X-adsorbates	1206:1221	The interfacial interaction has been elaborated on for composites (ZnO/X) as well as their complexes (ZnO- and ZnO/X-adsorbates).					
36889472	6	21	dep	complexes	1186:1194	arg1	ZnO-					1197:1200	ZnO-	1197:1200	ZnO-	1197:1200	The interfacial interaction has been elaborated on for composites (ZnO/X) as well as their complexes (ZnO- and ZnO/X-adsorbates).					
36889472	5	22	theme	intermediates	1067:1079	arg1	structures					1042:1051	geometrical/electronic structures	1019:1051	geometrical/electronic structures	1019:1051	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	5	22	theme	intermediates	1067:1079	arg1	thermodynamics					1000:1013	the calculated thermodynamics	985:1013	the calculated thermodynamics	985:1013	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	5	23	theme	best	932:935	arg1	performance					953:963	the best NO2 gas-sensing performance	928:963	the best NO2 gas-sensing performance	928:963	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	3	24	theme	zinc	518:521	arg1	cellulose					570:578	cellulose	570:578	cellulose	570:578	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	24	theme	zinc	518:521	arg1	oxide					523:527	zinc oxide	518:527	zinc oxide (ZnO)	518:533	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	3	24	theme	zinc	518:521	arg1	ZnO					530:532	ZnO	530:532	ZnO	530:532	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	0	25	theme	graphitic	26:34	arg1	nitride					43:49	graphitic carbon nitride	26:49	graphitic carbon nitride	26:49	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	5	26	theme	NO2	937:939	arg1	performance					953:963	the best NO2 gas-sensing performance	928:963	the best NO2 gas-sensing performance	928:963	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	7	27	theme	experimental	1257:1268	arg1	findings					1270:1277	experimental findings	1257:1277	experimental findings	1257:1277	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	5	28	theme	gas-sensing	941:951	arg1	performance					953:963	the best NO2 gas-sensing performance	928:963	the best NO2 gas-sensing performance	928:963	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	0	29	theme	graphene	16:23	arg1	coupling					4:11	The coupling	0:11	The coupling of graphene, graphitic carbon nitride and cellulose	0:63	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	1	30	theme	sense	206:210	arg1	dioxide					227:233	sense toxic nitrogen dioxide	206:233	sense toxic nitrogen dioxide (NO2)	206:239	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	1	30	theme	sense	206:210	arg1	NO2					236:238	NO2	236:238	NO2	236:238	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	0	31	theme	nitride	43:49	arg1	coupling					4:11	The coupling	0:11	The coupling of graphene, graphitic carbon nitride and cellulose	0:63	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	5	32	theme	geometrical/electronic	1019:1040	arg1	structures					1042:1051	geometrical/electronic structures	1019:1051	geometrical/electronic structures	1019:1051	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	0	33	theme	pollutant	143:151	arg1	dioxide					162:168	air pollutant nitrogen dioxide	139:168	air pollutant nitrogen dioxide	139:168	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	5	34	theme	formed	893:898	arg1	composites					900:909	the formed composites	889:909	the formed composites	889:909	Of the formed composites, ZnO/Gr exhibits the best NO2 gas-sensing performance, which is proved by the calculated thermodynamics and geometrical/electronic structures of reactants, intermediates and products.					
36889472	2	35	theme	oxide-based	306:316	arg1	sensors					322:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	0	36	theme	carbon	36:41	arg1	nitride					43:49	graphitic carbon nitride	26:49	graphitic carbon nitride	26:49	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	1	37	theme	prominent	275:283	arg1	pollutants					289:298	the most prominent air pollutants	266:298	the most prominent air pollutants	266:298	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	0	38	theme	air	139:141	arg1	dioxide					162:168	air pollutant nitrogen dioxide	139:168	air pollutant nitrogen dioxide	139:168	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	2	39	theme	Zinc	301:304	arg1	sensors					322:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors	301:328	Zinc oxide-based gas sensors are known to detect NO2 gas efficiently, however, the sensing mechanism and involved intermediates structures remain underexplored.					
36889472	1	40	theme	air	285:287	arg1	pollutants					289:298	the most prominent air pollutants	266:298	the most prominent air pollutants	266:298	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	7	41	theme	current	1229:1235	arg1	study					1237:1241	The current study	1225:1241	The current study	1225:1241	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	6	42	theme	interfacial	1099:1109	arg1	interaction					1111:1121	The interfacial interaction	1095:1121	The interfacial interaction	1095:1121	The interfacial interaction has been elaborated on for composites (ZnO/X) as well as their complexes (ZnO- and ZnO/X-adsorbates).					
36889472	4	43	theme	adsorbing	706:714	arg1	NO2					716:718	adsorbing NO2	706:718	adsorbing NO2 over ambient O2	706:734	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	7	44	dep	design	1301:1306	arg1	materials					1338:1346	materials	1338:1346	materials	1338:1346	The current study well explains experimental findings and opens up a way to design and unearth novel NO2 sensing materials.					
36889472	1	45	theme	toxic	212:216	arg1	dioxide					227:233	sense toxic nitrogen dioxide	206:233	sense toxic nitrogen dioxide (NO2)	206:239	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	1	45	theme	toxic	212:216	arg1	NO2					236:238	NO2	236:238	NO2	236:238	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	0	46	theme	nitrogen	153:160	arg1	dioxide					162:168	air pollutant nitrogen dioxide	139:168	air pollutant nitrogen dioxide	139:168	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	1	47	theme	nitrogen	218:225	arg1	dioxide					227:233	sense toxic nitrogen dioxide	206:233	sense toxic nitrogen dioxide (NO2)	206:239	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	1	47	theme	nitrogen	218:225	arg1	NO2					236:238	NO2	236:238	NO2	236:238	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	0	48	theme	cellulose	55:63	arg1	coupling					4:11	The coupling	0:11	The coupling of graphene, graphitic carbon nitride and cellulose	0:63	The coupling of graphene, graphitic carbon nitride and cellulose to fabricate zinc oxide-based sensors and their enhanced activity towards air pollutant nitrogen dioxide.					
36889472	4	49	theme	zinc	803:806	arg1	oxide					808:812	zinc oxide	803:812	zinc oxide	803:812	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	4	50	from	impact	847:852	arg1	sensitivity					873:883	the sensitivity	869:883	the sensitivity	869:883	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	4	51	theme	non-negligible	832:845	arg1	impact					847:852	the non-negligible impact	828:852	the non-negligible impact of humidity on the sensitivity	828:883	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
36889472	1	52	theme	pollutants	289:298	arg1	one					259:261	one	259:261	one	259:261	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	1	52	theme	pollutants	289:298	arg1	pollutants					289:298	the most prominent air pollutants	266:298	the most prominent air pollutants	266:298	It is desirable but challenging to sense toxic nitrogen dioxide (NO2) for it has become one of the most prominent air pollutants.					
36889472	3	53	theme	ZnO/X	554:558	arg1	[X = Cel					560:567	ZnO/X [X = Cel	554:567	ZnO/X [X = Cel	554:567	In the work, a series of sensitive materials, including zinc oxide (ZnO) and its composites ZnO/X [X = Cel (cellulose), CN (g-C3N4) and Gr (graphene)] have been comprehensively examined by density functional theory.					
36889472	4	54	with	line	818:821	arg1	impact					847:852	the non-negligible impact	828:852	the non-negligible impact of humidity on the sensitivity	828:883	It is found that ZnO favors adsorbing NO2 over ambient O2, and produces nitrate intermediates; and H2O is chemically held by zinc oxide, in line with the non-negligible impact of humidity on the sensitivity.					
35901072	8	0	theme	GAG	1055:1057	arg1	analysis					1071:1078	GAG composition analysis	1055:1078	GAG composition analysis	1055:1078	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	1	1	theme	non-syndromic	156:168	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	1	theme	non-syndromic	156:168	arg1	DFNA9					205:209	DFNA9	205:209	DFNA9	205:209	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	1	theme	non-syndromic	156:168	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	9	2	theme	cell	1324:1327	arg1	growth					1329:1334	cell growth	1324:1334	cell growth	1324:1334	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	7	3	theme	DFNA9	1031:1035	arg1	patients					1037:1044	DFNA9 patients	1031:1044	DFNA9 patients	1031:1044	The binding of cochlin to GAG was diminished by all of the point mutations found in DFNA9 patients.					
35901072	1	4	theme	autosomal	170:178	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	4	theme	autosomal	170:178	arg1	DFNA9					205:209	DFNA9	205:209	DFNA9	205:209	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	4	theme	autosomal	170:178	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	7	5	located	found	1022:1026	arg1	patients					1037:1044	DFNA9 patients	1031:1044	DFNA9 patients	1031:1044	The binding of cochlin to GAG was diminished by all of the point mutations found in DFNA9 patients.					
35901072	7	5	located	found	1022:1026	arg2	mutations					1012:1020	the point mutations	1002:1020	the point mutations found in DFNA9 patients	1002:1044	The binding of cochlin to GAG was diminished by all of the point mutations found in DFNA9 patients.					
35901072	0	6	theme	dominant	103:110	arg1	DFNA9					137:141	DFNA9	137:141	DFNA9	137:141	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	0	6	theme	dominant	103:110	arg1	loss					131:134	autosomal dominant late-onset hearing loss	93:134	autosomal dominant late-onset hearing loss (DFNA9)	93:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	0	7	from	Involvement	0:10	arg1	pathophysiology					74:88	the pathophysiology	70:88	the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9)	70:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	9	8	theme	autosomal	1504:1512	arg1	loss					1542:1545	autosomal dominant late-onset hearing loss	1504:1545	autosomal dominant late-onset hearing loss	1504:1545	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	0	9	theme	autosomal	93:101	arg1	DFNA9					137:141	DFNA9	137:141	DFNA9	137:141	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	0	9	theme	autosomal	93:101	arg1	loss					131:134	autosomal dominant late-onset hearing loss	93:134	autosomal dominant late-onset hearing loss (DFNA9)	93:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	4	10	with	interaction	661:671	arg1	s					700:700	s	700:700	s	700:700	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	4	10	with	interaction	661:671	arg1	ligand					693:698	its ligand	689:698	its ligand(s)	689:701	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	3	11	theme	cochlins	486:493	arg1	properties					450:459	the properties	446:459	the properties of wild-type and mutated cochlins derived from DFNA9	446:512	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	9	12	theme	transduction	1375:1386	arg1	mechanisms					1388:1397	signal transduction mechanisms	1368:1397	signal transduction mechanisms	1368:1397	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	0	13	theme	hearing	123:129	arg1	DFNA9					137:141	DFNA9	137:141	DFNA9	137:141	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	0	13	theme	hearing	123:129	arg1	loss					131:134	autosomal dominant late-onset hearing loss	93:134	autosomal dominant late-onset hearing loss (DFNA9)	93:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	8	14	theme	mouse	1195:1199	arg1	tissue					1209:1214	mouse cochlea tissue	1195:1214	mouse cochlea tissue	1195:1214	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	1	15	theme	dominant	180:187	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	15	theme	dominant	180:187	arg1	DFNA9					205:209	DFNA9	205:209	DFNA9	205:209	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	15	theme	dominant	180:187	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	0	16	theme	late-onset	112:121	arg1	DFNA9					137:141	DFNA9	137:141	DFNA9	137:141	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	0	16	theme	late-onset	112:121	arg1	loss					131:134	autosomal dominant late-onset hearing loss	93:134	autosomal dominant late-onset hearing loss (DFNA9)	93:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	7	17	theme	point	1006:1010	arg1	mutations					1012:1020	the point mutations	1002:1020	the point mutations found in DFNA9 patients	1002:1044	The binding of cochlin to GAG was diminished by all of the point mutations found in DFNA9 patients.					
35901072	9	18	theme	important	1306:1314	arg1	role					1316:1319	an important role	1303:1319	an important role	1303:1319	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	9	18	theme	important	1306:1314	arg1	co-receptors					1352:1363	co-receptors	1352:1363	co-receptors of signal transduction mechanisms	1352:1397	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	1	19	theme	hearing	189:195	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	19	theme	hearing	189:195	arg1	DFNA9					205:209	DFNA9	205:209	DFNA9	205:209	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	19	theme	hearing	189:195	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	8	20	theme	mouse	1105:1109	arg1	protein					1144:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	9	21	with	interaction	1404:1414	arg1	GAGs					1432:1435	GAGs	1432:1435	GAGs	1432:1435	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	3	22	theme	underlying	541:550	arg1	mechanism					563:571	the underlying pathogenic mechanism	537:571	the underlying pathogenic mechanism	537:571	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	3	23	theme	biochemical	395:405	arg1	studies					419:425	biochemical and genetic studies	395:425	biochemical and genetic studies	395:425	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	1	24	theme	coagulation	263:273	arg1	COCH					299:302	COCH	299:302	COCH	299:302	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	24	theme	coagulation	263:273	arg1	gene					293:296	the coagulation factor C homology gene	259:296	the coagulation factor C homology gene (COCH)	259:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	8	25	theme	sulfated	1178:1185	arg1	GAGs					1187:1190	moderately sulfated GAGs	1167:1190	moderately sulfated GAGs	1167:1190	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	9	26	from	interaction	1404:1414	arg1	matrix					1458:1463	the extracellular matrix	1440:1463	the extracellular matrix	1440:1463	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	3	27	theme	pathogenic	552:561	arg1	mechanism					563:571	the underlying pathogenic mechanism	537:571	the underlying pathogenic mechanism	537:571	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	9	28	theme	signal	1368:1373	arg1	mechanisms					1388:1397	signal transduction mechanisms	1368:1397	signal transduction mechanisms	1368:1397	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	0	29	theme	binding	23:29	arg1	Involvement					0:10	Involvement	0:10	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).	0:143	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	1	30	theme	factor	275:280	arg1	COCH					299:302	COCH	299:302	COCH	299:302	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	30	theme	factor	275:280	arg1	gene					293:296	the coagulation factor C homology gene	259:296	the coagulation factor C homology gene (COCH)	259:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	9	31	theme	mechanisms	1388:1397	arg1	role					1316:1319	an important role	1303:1319	an important role	1303:1319	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	9	31	theme	mechanisms	1388:1397	arg1	co-receptors					1352:1363	co-receptors	1352:1363	co-receptors of signal transduction mechanisms	1352:1397	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	4	32	theme	cochlin	606:612	arg1	cell					623:626	a cochlin reporter cell	604:626	a cochlin reporter cell	604:626	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	0	33	theme	cochlin	15:21	arg1	binding					23:29	cochlin binding	15:29	cochlin binding to sulfated heparan sulfate/heparin	15:65	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	1	34	theme	C	282:282	arg1	COCH					299:302	COCH	299:302	COCH	299:302	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	34	theme	C	282:282	arg1	gene					293:296	the coagulation factor C homology gene	259:296	the coagulation factor C homology gene (COCH)	259:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	0	35	theme	loss	131:134	arg1	pathophysiology					74:88	the pathophysiology	70:88	the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9)	70:142	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	8	36	theme	such	1252:1255	arg1	GAGs					1266:1269	such sulfated GAGs	1252:1269	such sulfated GAGs	1252:1269	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	9	37	theme	extracellular	1444:1456	arg1	matrix					1458:1463	the extracellular matrix	1440:1463	the extracellular matrix	1440:1463	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	5	38	theme	sulfated	767:774	arg1	glycosaminoglycans					776:793	highly sulfated glycosaminoglycans	760:793	highly sulfated glycosaminoglycans (GAGs)	760:800	We found a class of highly sulfated glycosaminoglycans (GAGs), heparin, that were selectively bound to cochlin.					
35901072	5	38	theme	sulfated	767:774	arg1	GAGs					796:799	GAGs	796:799	GAGs	796:799	We found a class of highly sulfated glycosaminoglycans (GAGs), heparin, that were selectively bound to cochlin.					
35901072	5	38	theme	sulfated	767:774	arg1	heparin					803:809	heparin	803:809	heparin	803:809	We found a class of highly sulfated glycosaminoglycans (GAGs), heparin, that were selectively bound to cochlin.					
35901072	0	39	theme	sulfated	34:41	arg1	sulfate/heparin					51:65	sulfated heparan sulfate/heparin	34:65	sulfated heparan sulfate/heparin	34:65	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	1	40	theme	homology	284:291	arg1	COCH					299:302	COCH	299:302	COCH	299:302	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	40	theme	homology	284:291	arg1	gene					293:296	the coagulation factor C homology gene	259:296	the coagulation factor C homology gene (COCH)	259:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	5	41	theme	glycosaminoglycans	776:793	arg1	class					751:755	a class	749:755	a class	749:755	We found a class of highly sulfated glycosaminoglycans (GAGs), heparin, that were selectively bound to cochlin.					
35901072	9	42	theme	dominant	1514:1521	arg1	loss					1542:1545	autosomal dominant late-onset hearing loss	1504:1545	autosomal dominant late-onset hearing loss	1504:1545	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	2	43	theme	matrix	380:385	arg1	component					340:348	a major component	332:348	a major component of the cochlear extracellular matrix	332:385	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	2	43	theme	matrix	380:385	arg1	cochlin					323:329	cochlin	323:329	cochlin	323:329	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	2	44	theme	cochlear	357:364	arg1	matrix					380:385	the cochlear extracellular matrix	353:385	the cochlear extracellular matrix	353:385	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	1	45	from	mutations	246:254	arg1	COCH					299:302	COCH	299:302	COCH	299:302	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	45	from	mutations	246:254	arg1	gene					293:296	the coagulation factor C homology gene	259:296	the coagulation factor C homology gene (COCH)	259:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	8	46	theme	fusion	1137:1142	arg1	protein					1144:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	2	47	theme	extracellular	366:378	arg1	matrix					380:385	the cochlear extracellular matrix	353:385	the cochlear extracellular matrix	353:385	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	9	48	theme	pathological	1479:1490	arg1	research					1492:1499	the pathological research	1475:1499	the pathological research of autosomal dominant late-onset hearing loss in DFNA9	1475:1554	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	7	49	theme	cochlin	962:968	arg1	binding					951:957	The binding	947:957	The binding of cochlin to GAG	947:975	The binding of cochlin to GAG was diminished by all of the point mutations found in DFNA9 patients.					
35901072	3	50	theme	genetic	411:417	arg1	studies					419:425	biochemical and genetic studies	395:425	biochemical and genetic studies	395:425	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	9	51	theme	hearing	1534:1540	arg1	loss					1542:1545	autosomal dominant late-onset hearing loss	1504:1545	autosomal dominant late-onset hearing loss	1504:1545	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	4	52	theme	cochlin	676:682	arg1	interaction					661:671	the interaction	657:671	the interaction of cochlin with its ligand(s)	657:701	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	0	53	theme	heparan	43:49	arg1	sulfate/heparin					51:65	sulfated heparan sulfate/heparin	34:65	sulfated heparan sulfate/heparin	34:65	Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).					
35901072	9	54	theme	loss	1542:1545	arg1	research					1492:1499	the pathological research	1475:1499	the pathological research of autosomal dominant late-onset hearing loss in DFNA9	1475:1554	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	3	55	attach	derived	495:501	arg2	cochlins					486:493	wild-type and mutated cochlins	464:493	wild-type and mutated cochlins derived from DFNA9	464:512	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	3	55	attach	derived	495:501	arg1	DFNA9					508:512	DFNA9	508:512	DFNA9	508:512	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	3	56	theme	mutated	478:484	arg1	cochlins					486:493	wild-type and mutated cochlins	464:493	wild-type and mutated cochlins derived from DFNA9	464:512	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	9	57	theme	late-onset	1523:1532	arg1	loss					1542:1545	autosomal dominant late-onset hearing loss	1504:1545	autosomal dominant late-onset hearing loss	1504:1545	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	9	58	theme	cochlin	1419:1425	arg1	interaction					1404:1414	the interaction	1400:1414	the interaction of cochlin with GAGs in the extracellular matrix	1400:1463	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	4	59	theme	β-galactosidase	717:731	arg1	assay					733:737	a β-galactosidase assay	715:737	a β-galactosidase assay	715:737	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	3	60	theme	wild-type	464:472	arg1	cochlins					486:493	wild-type and mutated cochlins	464:493	wild-type and mutated cochlins derived from DFNA9	464:512	Though biochemical and genetic studies have characterized the properties of wild-type and mutated cochlins derived from DFNA9, little is known about the underlying pathogenic mechanism.					
35901072	8	61	theme	sulfated	1257:1264	arg1	GAGs					1266:1269	such sulfated GAGs	1252:1269	such sulfated GAGs	1252:1269	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	1	62	theme	hearing	217:223	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	62	theme	hearing	217:223	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	4	63	theme	reporter	614:621	arg1	cell					623:626	a cochlin reporter cell	604:626	a cochlin reporter cell	604:626	In this study, we established a cochlin reporter cell, which allowed us to monitor the interaction of cochlin with its ligand(s) by means of a β-galactosidase assay.					
35901072	8	64	theme	cochlea	1201:1207	arg1	tissue					1209:1214	mouse cochlea tissue	1195:1214	mouse cochlea tissue	1195:1214	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	2	65	theme	major	334:338	arg1	component					340:348	a major component	332:348	a major component of the cochlear extracellular matrix	332:385	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	2	65	theme	major	334:338	arg1	cochlin					323:329	cochlin	323:329	cochlin	323:329	COCH encodes for cochlin, a major component of the cochlear extracellular matrix.					
35901072	9	66	from	research	1492:1499	arg1	DFNA9					1550:1554	DFNA9	1550:1554	DFNA9	1550:1554	Since GAGs play an important role in cell growth and survival as co-receptors of signal transduction mechanisms, the interaction of cochlin with GAGs in the extracellular matrix could aid the pathological research of autosomal dominant late-onset hearing loss in DFNA9.					
35901072	8	67	theme	cochlin/immunoglobulin-Fc	1111:1135	arg1	protein					1144:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	mouse cochlin/immunoglobulin-Fc fusion protein	1105:1150	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
35901072	1	68	theme	Late-onset	145:154	arg1	loss					197:200	Late-onset non-syndromic autosomal dominant hearing loss 9	145:202	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9)	145:210	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	68	theme	Late-onset	145:154	arg1	DFNA9					205:209	DFNA9	205:209	DFNA9	205:209	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	1	68	theme	Late-onset	145:154	arg1	impairment					225:234	a hearing impairment	215:234	a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH)	215:303	Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH).					
35901072	8	69	theme	composition	1059:1069	arg1	analysis					1071:1078	GAG composition analysis	1055:1078	GAG composition analysis	1055:1078	Through GAG composition analysis and immunostaining using mouse cochlin/immunoglobulin-Fc fusion protein, we identified moderately sulfated GAGs in mouse cochlea tissue; this implies that cochlin binds to such sulfated GAGs in the cochlea.					
36481333	8	0	theme	food	1086:1089	arg1	film					1101:1104	intelligent food packaging film	1074:1104	intelligent food packaging film	1074:1104	The results suggested that the Gel/Csa/PVA/LE film could be applied to intelligent food packaging film to indicate the freshness of fish.					
36481333	7	1	theme	pH	937:938	arg1	sensitivity					940:950	the pH sensitivity	933:950	the pH sensitivity to show an obvious color change at 25 °C, 1th day	933:1000	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	1	2	theme	shell	156:160	arg1	LE					171:172	LE	171:172	LE	171:172	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	1	2	theme	shell	156:160	arg1	extract					162:168	The anthocyanin-rich litchi shell extract	128:168	The anthocyanin-rich litchi shell extract (LE)	128:173	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	6	3	theme	extract	680:686	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	1	4	theme	packaging	236:244	arg1	films					256:260	active/intelligent food packaging composite films	212:260	active/intelligent food packaging composite films	212:260	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	8	5	theme	intelligent	1074:1084	arg1	film					1101:1104	intelligent food packaging film	1074:1104	intelligent food packaging film	1074:1104	The results suggested that the Gel/Csa/PVA/LE film could be applied to intelligent food packaging film to indicate the freshness of fish.					
36481333	6	6	theme	shell	674:678	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	1	7	theme	composite	246:254	arg1	films					256:260	active/intelligent food packaging composite films	212:260	active/intelligent food packaging composite films	212:260	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	0	8	theme	shell	97:101	arg1	extract					103:109	litchi shell extract	90:109	litchi shell extract	90:109	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	4	9	theme	red	520:522	arg1	degrees					509:515	different degrees	499:515	different degrees of red	499:522	The composite films with LE showed different degrees of red.					
36481333	3	10	contain	had	401:403	arg1	films					374:378	the composite films	360:378	the composite films incorporated with LE	360:399	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	3	10	contain	had	401:403	arg2	cross-sections					448:461	texture-oriented layered, compact, uniform cross-sections	405:461	texture-oriented layered, compact, uniform cross-sections	405:461	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	6	11	theme	alcohol/litchi	659:672	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	3	12	theme	composite	364:372	arg1	films					374:378	the composite films	360:378	the composite films incorporated with LE	360:399	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	7	13	theme	color	971:975	arg1	change					977:982	an obvious color change	960:982	an obvious color change	960:982	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	7	14	theme	Gel/Csa/PVA/LE	909:922	arg1	film					924:927	the Gel/Csa/PVA/LE film	905:927	the Gel/Csa/PVA/LE film	905:927	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	4	15	with	films	478:482	arg1	LE					489:490	LE	489:490	LE	489:490	The composite films with LE showed different degrees of red.					
36481333	0	16	theme	food	41:44	arg1	composite					56:64	intelligent pH food packaging composite	26:64	intelligent pH food packaging composite	26:64	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	4	17	theme	different	499:507	arg1	degrees					509:515	different degrees	499:515	different degrees of red	499:522	The composite films with LE showed different degrees of red.					
36481333	3	18	theme	layered	422:428	arg1	cross-sections					448:461	texture-oriented layered, compact, uniform cross-sections	405:461	texture-oriented layered, compact, uniform cross-sections	405:461	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	7	19	contain	had	929:931	arg1	film					924:927	the Gel/Csa/PVA/LE film	905:927	the Gel/Csa/PVA/LE film	905:927	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	7	19	contain	had	929:931	arg2	sensitivity					940:950	the pH sensitivity	933:950	the pH sensitivity to show an obvious color change at 25 °C, 1th day	933:1000	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	6	20	theme	gelatin/chitosan/polyvinyl	632:657	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	3	21	dep	layered	422:428	arg1	uniform					440:446	uniform	440:446	uniform	440:446	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	3	21	dep	layered	422:428	arg1	compact					431:437	compact	431:437	compact	431:437	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	6	22	theme	at	801:802	arg1	break					804:808	elongation at break	790:808	elongation at break (116 %)	790:816	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	22	theme	at	801:802	arg1	%					815:815	116 %	811:815	116 %	811:815	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	8	23	theme	Gel/Csa/PVA/LE	1034:1047	arg1	film					1049:1052	the Gel/Csa/PVA/LE film	1030:1052	the Gel/Csa/PVA/LE film	1030:1052	The results suggested that the Gel/Csa/PVA/LE film could be applied to intelligent food packaging film to indicate the freshness of fish.					
36481333	0	24	theme	litchi	90:95	arg1	extract					103:109	litchi shell extract	90:109	litchi shell extract	90:109	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	6	25	theme	elongation	790:799	arg1	break					804:808	elongation at break	790:808	elongation at break (116 %)	790:816	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	25	theme	elongation	790:799	arg1	%					815:815	116 %	811:815	116 %	811:815	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	2	26	theme	films	310:314	arg1	properties					286:295	properties	286:295	properties	286:295	The microstructure and properties of composite films were characterized.					
36481333	2	26	theme	films	310:314	arg1	microstructure					267:280	microstructure	267:280	microstructure	267:280	The microstructure and properties of composite films were characterized.					
36481333	8	27	theme	fish	1135:1138	arg1	freshness					1122:1130	the freshness	1118:1130	the freshness of fish	1118:1138	The results suggested that the Gel/Csa/PVA/LE film could be applied to intelligent food packaging film to indicate the freshness of fish.					
36481333	2	28	theme	composite	300:308	arg1	films					310:314	composite films	300:314	composite films	300:314	The microstructure and properties of composite films were characterized.					
36481333	6	29	theme	blocking	724:731	arg1	rates					733:737	better UV blocking rates	714:737	better UV blocking rates (0-20 %)	714:746	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	29	theme	blocking	724:731	arg1	%					745:745	0-20 %	740:745	0-20 %	740:745	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	0	30	theme	active	15:20	arg1	films					66:70	active and intelligent pH food packaging composite films	15:70	active and intelligent pH food packaging composite films	15:70	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	6	31	theme	UV	721:722	arg1	rates					733:737	better UV blocking rates	714:737	better UV blocking rates (0-20 %)	714:746	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	31	theme	UV	721:722	arg1	%					745:745	0-20 %	740:745	0-20 %	740:745	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	2	32	dep	microstructure	267:280	arg1	The					263:265	The	263:265	The	263:265	The microstructure and properties of composite films were characterized.					
36481333	0	33	theme	pH	38:39	arg1	composite					56:64	intelligent pH food packaging composite	26:64	intelligent pH food packaging composite	26:64	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	6	34	theme	better	714:719	arg1	rates					733:737	better UV blocking rates	714:737	better UV blocking rates (0-20 %)	714:746	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	34	theme	better	714:719	arg1	%					745:745	0-20 %	740:745	0-20 %	740:745	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	35	from	break	804:808	arg1	at					801:802	elongation at break	790:808	elongation at break (116 %)	790:816	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	35	from	break	804:808	arg1	elongation					790:799	elongation at break	790:808	elongation at break (116 %)	790:816	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	0	36	theme	intelligent	26:36	arg1	composite					56:64	intelligent pH food packaging composite	26:64	intelligent pH food packaging composite	26:64	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	6	37	contain	had	710:712	arg2	%					815:815	116 %	811:815	116 %	811:815	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg2	rates					733:737	better UV blocking rates	714:737	better UV blocking rates (0-20 %)	714:746	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg2	%					745:745	0-20 %	740:745	0-20 %	740:745	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg2	break					804:808	elongation at break	790:808	elongation at break (116 %)	790:816	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg2	strength					766:773	the best tensile strength	749:773	the best tensile strength (18.6 MPa)	749:784	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg2	18.6 MPa					776:783	18.6 MPa	776:783	18.6 MPa	776:783	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	37	contain	had	710:712	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	5	38	theme	similar	549:555	arg1	1.62-1.65 × 10-12 g·cm/cm2·Pa·s					589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	38	theme	similar	549:555	arg1	rates					582:586	similar water vapor transmission rates	549:586	similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s)	549:620	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	6	39	theme	best	753:756	arg1	18.6 MPa					776:783	18.6 MPa	776:783	18.6 MPa	776:783	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	39	theme	best	753:756	arg1	strength					766:773	the best tensile strength	749:773	the best tensile strength (18.6 MPa)	749:784	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	0	40	theme	packaging	46:54	arg1	composite					56:64	intelligent pH food packaging composite	26:64	intelligent pH food packaging composite	26:64	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	4	41	theme	composite	468:476	arg1	films					478:482	The composite films	464:482	The composite films with LE	464:490	The composite films with LE showed different degrees of red.					
36481333	5	42	theme	water	557:561	arg1	1.62-1.65 × 10-12 g·cm/cm2·Pa·s					589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	42	theme	water	557:561	arg1	rates					582:586	similar water vapor transmission rates	549:586	similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s)	549:620	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	3	43	theme	texture-oriented	405:420	arg1	cross-sections					448:461	texture-oriented layered, compact, uniform cross-sections	405:461	texture-oriented layered, compact, uniform cross-sections	405:461	The results showed that the composite films incorporated with LE had texture-oriented layered, compact, uniform cross-sections.					
36481333	5	44	contain	had	545:547	arg1	films					539:543	The composite films	525:543	The composite films	525:543	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	44	contain	had	545:547	arg2	rates					582:586	similar water vapor transmission rates	549:586	similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s)	549:620	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	44	contain	had	545:547	arg2	1.62-1.65 × 10-12 g·cm/cm2·Pa·s					589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	45	theme	vapor	563:567	arg1	1.62-1.65 × 10-12 g·cm/cm2·Pa·s					589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	45	theme	vapor	563:567	arg1	rates					582:586	similar water vapor transmission rates	549:586	similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s)	549:620	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	8	46	theme	packaging	1091:1099	arg1	film					1101:1104	intelligent food packaging film	1074:1104	intelligent food packaging film	1074:1104	The results suggested that the Gel/Csa/PVA/LE film could be applied to intelligent food packaging film to indicate the freshness of fish.					
36481333	5	47	theme	transmission	569:580	arg1	1.62-1.65 × 10-12 g·cm/cm2·Pa·s					589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	1.62-1.65 × 10-12 g·cm/cm2·Pa·s	589:619	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	5	47	theme	transmission	569:580	arg1	rates					582:586	similar water vapor transmission rates	549:586	similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s)	549:620	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	7	48	theme	obvious	963:969	arg1	change					977:982	an obvious color change	960:982	an obvious color change	960:982	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	6	49	theme	tensile	758:764	arg1	18.6 MPa					776:783	18.6 MPa	776:783	18.6 MPa	776:783	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	6	49	theme	tensile	758:764	arg1	strength					766:773	the best tensile strength	749:773	the best tensile strength (18.6 MPa)	749:784	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	7	50	theme	composite	828:836	arg1	films					838:842	the composite films	824:842	the composite films monitored for fish	824:861	When the composite films monitored for fish freshness at 4 °C (10 d) and 25 °C (3 d), the Gel/Csa/PVA/LE film had the pH sensitivity to show an obvious color change at 25 °C, 1th day.					
36481333	0	51	theme	films	66:70	arg1	Development					0:10	Development	0:10	Development of active and intelligent pH food packaging composite films	0:70	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	5	52	theme	composite	529:537	arg1	films					539:543	The composite films	525:543	The composite films	525:543	The composite films had similar water vapor transmission rates (1.62-1.65 × 10-12 g·cm/cm2·Pa·s).					
36481333	1	53	theme	anthocyanin-rich	132:147	arg1	LE					171:172	LE	171:172	LE	171:172	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	1	53	theme	anthocyanin-rich	132:147	arg1	extract					162:168	The anthocyanin-rich litchi shell extract	128:168	The anthocyanin-rich litchi shell extract (LE)	128:173	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	6	54	theme	Gel/Csa/PVA/LE	689:702	arg1	film					705:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film	632:708	However, gelatin/chitosan/polyvinyl alcohol/litchi shell extract (Gel/Csa/PVA/LE) film had better UV blocking rates (0-20 %), the best tensile strength (18.6 MPa) and elongation at break (116 %).					
36481333	1	55	theme	active/intelligent	212:229	arg1	films					256:260	active/intelligent food packaging composite films	212:260	active/intelligent food packaging composite films	212:260	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	0	56	theme	composite	56:64	arg1	films					66:70	active and intelligent pH food packaging composite films	15:70	active and intelligent pH food packaging composite films	15:70	Development of active and intelligent pH food packaging composite films incorporated with litchi shell extract as an indicator.					
36481333	1	57	theme	litchi	149:154	arg1	LE					171:172	LE	171:172	LE	171:172	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	1	57	theme	litchi	149:154	arg1	extract					162:168	The anthocyanin-rich litchi shell extract	128:168	The anthocyanin-rich litchi shell extract (LE)	128:173	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36481333	1	58	theme	food	231:234	arg1	films					256:260	active/intelligent food packaging composite films	212:260	active/intelligent food packaging composite films	212:260	The anthocyanin-rich litchi shell extract (LE) was mixed with the matrix to prepare active/intelligent food packaging composite films.					
36087997	7	0	theme	rational	973:980	arg1	design					982:987	the rational design	969:987	the rational design of hydrogel precursors	969:1010	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	0	1	theme	acid	28:31	arg1	hydrogel					33:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	6	2	theme	adhesion	894:901	arg1	strength					903:910	significantly greater adhesion strength	872:910	significantly greater adhesion strength	872:910	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	0	3	theme	wound	105:109	arg1	closure					111:117	wound closure	105:117	wound closure	105:117	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	4	4	located	found	627:631	arg1	membranes					652:660	biological cell membranes	636:660	biological cell membranes	636:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	4	4	located	found	627:631	arg2	compounds					617:625	glycosyl compounds	608:625	glycosyl compounds found in biological cell membranes	608:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	7	5	theme	multiple	1071:1078	arg1	functionalities					1080:1094	multiple functionalities	1071:1094	multiple functionalities	1071:1094	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	3	6	theme	adhesive-based	439:452	arg1	hydrogel					430:437	the first single-component hyaluronic acid hydrogel	387:437	the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	387:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	8	7	theme	ideal	1148:1152	arg1	bio-adhesive					1154:1165	an ideal bio-adhesive	1145:1165	an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure	1145:1257	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	2	8	theme	formidable	325:334	arg1	challenge					336:344	a formidable challenge	323:344	a formidable challenge	323:344	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	4	9	theme	biological	636:645	arg1	membranes					652:660	biological cell membranes	636:660	biological cell membranes	636:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	3	10	theme	single-component	397:412	arg1	hydrogel					430:437	the first single-component hyaluronic acid hydrogel	387:437	the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	387:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	7	11	theme	single-component	1041:1056	arg1	networks					1058:1065	single-component networks	1041:1065	single-component networks	1041:1065	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	5	12	theme	strong	793:798	arg1	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	12	theme	strong	793:798	arg1	strength					812:819	strong compressive strength	793:819	strong compressive strength	793:819	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	13	theme	rheological	667:677	arg1	tests					695:699	The rheological and compressive tests	663:699	The rheological and compressive tests for the hydrogel	663:716	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	7	14	theme	networks	1058:1065	arg1	formation					1028:1036	the formation	1024:1036	the formation of single-component networks and multiple functionalities	1024:1094	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	5	15	theme	compressive	800:810	arg1	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	15	theme	compressive	800:810	arg1	strength					812:819	strong compressive strength	793:819	strong compressive strength	793:819	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	2	16	theme	reversible	296:305	arg1	adhesion					307:314	injectability, strong and reversible adhesion	270:314	injectability, strong and reversible adhesion	270:314	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	0	17	theme	hyaluronic	17:26	arg1	hydrogel					33:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	5	18	theme	compressive	683:693	arg1	tests					695:699	The rheological and compressive tests	663:699	The rheological and compressive tests for the hydrogel	663:716	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	0	19	theme	Single-component	0:15	arg1	hydrogel					33:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel	0:40	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	3	20	theme	hyaluronic	414:423	arg1	hydrogel					430:437	the first single-component hyaluronic acid hydrogel	387:437	the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	387:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	4	21	theme	adhesion	590:597	arg1	site					599:602	an adhesion site	587:602	an adhesion site for glycosyl compounds found in biological cell membranes	587:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	4	21	theme	adhesion	590:597	arg1	acid					511:514	Phenylboronic acid	497:514	Phenylboronic acid	497:514	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	5	22	theme	self-healing	745:756	arg1	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	22	theme	self-healing	745:756	arg1	injectability					775:787	good injectability	770:787	good injectability	770:787	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	22	theme	self-healing	745:756	arg1	strength					812:819	strong compressive strength	793:819	strong compressive strength	793:819	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	8	23	theme	In	1097:1098	arg1	studies					1105:1111	In vivo studies	1097:1111	In vivo studies	1097:1111	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	8	24	dep	In	1097:1098	arg1	vivo					1100:1103	vivo	1100:1103	vivo	1100:1103	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	3	25	theme	acid	425:428	arg1	hydrogel					430:437	the first single-component hyaluronic acid hydrogel	387:437	the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	387:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	4	26	theme	glycosyl	608:615	arg1	compounds					617:625	glycosyl compounds	608:625	glycosyl compounds found in biological cell membranes	608:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	8	27	theme	absorbed	1190:1197	arg1	exudate					1205:1211	absorbed wound exudate	1190:1211	absorbed wound exudate	1190:1211	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	1	28	dep	available	161:169	arg1	adhesives					136:144	Hydrogel tissue adhesives	120:144	Hydrogel tissue adhesives that currently available	120:169	Hydrogel tissue adhesives that currently available are often fabricated by mixing two or more polymeric components.					
36087997	3	29	theme	acid-diol	471:479	arg1	linkages					487:494	phenylboronic acid-diol ester linkages	457:494	phenylboronic acid-diol ester linkages	457:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	1	30	theme	polymeric	214:222	arg1	components					224:233	two or more polymeric components	202:233	two or more polymeric components	202:233	Hydrogel tissue adhesives that currently available are often fabricated by mixing two or more polymeric components.					
36087997	8	31	with	bio-adhesive	1154:1165	arg1	exudate					1205:1211	absorbed wound exudate	1190:1211	absorbed wound exudate	1190:1211	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	8	31	with	bio-adhesive	1154:1165	arg1	biocompatibility					1172:1187	biocompatibility	1172:1187	biocompatibility	1172:1187	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	8	31	with	bio-adhesive	1154:1165	arg1	closure					1251:1257	accelerated wound closure	1233:1257	accelerated wound closure	1233:1257	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	2	32	dep	afford	263:268	arg1	remain					316:321	remain	316:321	afford injectability, strong and reversible adhesion remain a formidable challenge	263:344	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	3	33	theme	ester	481:485	arg1	linkages					487:494	phenylboronic acid-diol ester linkages	457:494	phenylboronic acid-diol ester linkages	457:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	5	34	theme	good	770:773	arg1	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	34	theme	good	770:773	arg1	injectability					775:787	good injectability	770:787	good injectability	770:787	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	0	35	theme	phenylboronic	60:72	arg1	bonds					80:84	phenylboronic ester bonds	60:84	phenylboronic ester bonds for hemostasis and wound closure	60:117	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	3	36	theme	first	391:395	arg1	hydrogel					430:437	the first single-component hyaluronic acid hydrogel	387:437	the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	387:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	8	37	theme	wound	1245:1249	arg1	closure					1251:1257	accelerated wound closure	1233:1257	accelerated wound closure	1233:1257	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	2	38	theme	Single-component	236:251	arg1	hydrogels					253:261	Single-component hydrogels	236:261	Single-component hydrogels	236:261	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	6	39	theme	Adhesion	822:829	arg1	tests					831:835	Adhesion tests	822:835	Adhesion tests	822:835	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	1	40	theme	Hydrogel	120:127	arg1	adhesives					136:144	Hydrogel tissue adhesives	120:144	Hydrogel tissue adhesives that currently available	120:169	Hydrogel tissue adhesives that currently available are often fabricated by mixing two or more polymeric components.					
36087997	3	41	theme	phenylboronic	457:469	arg1	linkages					487:494	phenylboronic acid-diol ester linkages	457:494	phenylboronic acid-diol ester linkages	457:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	8	42	theme	wound	1199:1203	arg1	exudate					1205:1211	absorbed wound exudate	1190:1211	absorbed wound exudate	1190:1211	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	6	43	theme	fibrin	928:933	arg1	glue					935:938	commercial fibrin glue	917:938	commercial fibrin glue	917:938	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	1	44	theme	tissue	129:134	arg1	adhesives					136:144	Hydrogel tissue adhesives	120:144	Hydrogel tissue adhesives that currently available	120:169	Hydrogel tissue adhesives that currently available are often fabricated by mixing two or more polymeric components.					
36087997	7	45	theme	hydrogel	992:999	arg1	precursors					1001:1010	hydrogel precursors	992:1010	hydrogel precursors	992:1010	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	8	46	theme	accelerated	1233:1243	arg1	closure					1251:1257	accelerated wound closure	1233:1257	accelerated wound closure	1233:1257	In vivo studies further proved the hydrogel was an ideal bio-adhesive with biocompatibility, absorbed wound exudate and hemostasis, and accelerated wound closure.					
36087997	6	47	theme	commercial	917:926	arg1	glue					935:938	commercial fibrin glue	917:938	commercial fibrin glue	917:938	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	6	48	theme	greater	886:892	arg1	strength					903:910	significantly greater adhesion strength	872:910	significantly greater adhesion strength	872:910	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	7	49	theme	precursors	1001:1010	arg1	design					982:987	the rational design	969:987	the rational design of hydrogel precursors	969:1010	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	5	50	theme	excellent	735:743	arg1	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	50	theme	excellent	735:743	arg1	injectability					775:787	good injectability	770:787	good injectability	770:787	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	50	theme	excellent	735:743	arg1	strength					812:819	strong compressive strength	793:819	strong compressive strength	793:819	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	2	51	theme	strong	285:290	arg1	adhesion					307:314	injectability, strong and reversible adhesion	270:314	injectability, strong and reversible adhesion	270:314	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	4	52	theme	cell	647:650	arg1	membranes					652:660	biological cell membranes	636:660	biological cell membranes	636:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	6	53	contain	has	868:870	arg2	strength					903:910	significantly greater adhesion strength	872:910	significantly greater adhesion strength	872:910	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	6	53	contain	has	868:870	arg1	hydrogel					859:866	the hydrogel	855:866	the hydrogel	855:866	Adhesion tests demonstrated that the hydrogel has significantly greater adhesion strength than commercial fibrin glue.					
36087997	4	54	theme	Phenylboronic	497:509	arg1	cross-linker					540:551	a cross-linker	538:551	a cross-linker	538:551	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	4	54	theme	Phenylboronic	497:509	arg1	site					599:602	an adhesion site	587:602	an adhesion site for glycosyl compounds found in biological cell membranes	587:660	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	4	54	theme	Phenylboronic	497:509	arg1	acid					511:514	Phenylboronic acid	497:514	Phenylboronic acid	497:514	Phenylboronic acid can not only serve as a cross-linker to form hydrogel, but also act as an adhesion site for glycosyl compounds found in biological cell membranes.					
36087997	0	55	theme	ester	74:78	arg1	bonds					80:84	phenylboronic ester bonds	60:84	phenylboronic ester bonds for hemostasis and wound closure	60:117	Single-component hyaluronic acid hydrogel adhesive based on phenylboronic ester bonds for hemostasis and wound closure.					
36087997	2	56	theme	injectability	270:282	arg1	adhesion					307:314	injectability, strong and reversible adhesion	270:314	injectability, strong and reversible adhesion	270:314	Single-component hydrogels afford injectability, strong and reversible adhesion remain a formidable challenge.					
36087997	7	57	theme	functionalities	1080:1094	arg1	formation					1028:1036	the formation	1024:1036	the formation of single-component networks and multiple functionalities	1024:1094	These findings suggest that the rational design of hydrogel precursors facilitates the formation of single-component networks and multiple functionalities.					
36087997	3	58	theme	hydrogel	430:437	arg1	creation					375:382	the creation	371:382	the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages	371:494	This research describes the creation of the first single-component hyaluronic acid hydrogel adhesive-based on phenylboronic acid-diol ester linkages.					
36087997	5	59	contain	has	731:733	arg2	injectability					775:787	good injectability	770:787	good injectability	770:787	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	59	contain	has	731:733	arg2	properties					758:767	excellent self-healing properties	735:767	excellent self-healing properties	735:767	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	59	contain	has	731:733	arg1	it					728:729	it	728:729	it	728:729	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
36087997	5	59	contain	has	731:733	arg2	strength					812:819	strong compressive strength	793:819	strong compressive strength	793:819	The rheological and compressive tests for the hydrogel show that it has excellent self-healing properties, good injectability and strong compressive strength.					
35385837	7	0	theme	promising	1024:1032	arg1	route					1034:1038	a promising route	1022:1038	a promising route for manufacturing environmental SSBs	1022:1075	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	1	1	theme	room	177:180	arg1	temperature					182:192	high room temperature	172:192	high room temperature ionic conductivity	172:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	2	theme	batteries	290:298	arg1	application					251:261	the practical application	237:261	the practical application of high-safety solid-state batteries (SSBs)	237:305	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	0	3	theme	metal	108:112	arg1	batteries					114:122	ambient-temperature lithium metal batteries	80:122	ambient-temperature lithium metal batteries	80:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	1	4	theme	temperature	182:192	arg1	conductivity					200:211	high room temperature ionic conductivity	172:211	high room temperature ionic conductivity	172:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	6	5	theme	retention	904:912	arg1	capacity					849:856	an initial discharge specific capacity	819:856	an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	819:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	6	theme	situphoto-polymerization	485:508	arg1	method					510:515	thein situphoto-polymerization method	479:515	thein situphoto-polymerization method	479:515	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	7	7	theme	polymer-polymer	977:991	arg1	configuration					997:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	2	8	theme	flexible	316:323	arg1	film					350:353	a flexible polymer-polymer CPE thin film	314:353	a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	314:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	6	9	theme	specific	840:847	arg1	capacity					849:856	an initial discharge specific capacity	819:856	an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	819:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	10	dep	three-dimensional	371:387	arg1	3D					390:391	3D	390:391	3D	390:391	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	7	11	from	nature	1134:1139	arg1	abundant					1122:1129	abundant	1122:1129	abundant	1122:1129	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	6	12	theme	discharge	830:838	arg1	capacity					849:856	an initial discharge specific capacity	819:856	an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	819:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	1	13	theme	ionic	194:198	arg1	conductivity					200:211	high room temperature ionic conductivity	172:211	high room temperature ionic conductivity	172:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	5	14	theme	h	779:779	arg1	cycles					754:759	stable cycles	747:759	stable cycles of more than 1200 h	747:779	The Li∣BC-CPE∣Li symmetric cell manifested stable cycles of more than 1200 h.					
35385837	1	15	with	films	161:165	arg1	conductivity					200:211	high room temperature ionic conductivity	172:211	high room temperature ionic conductivity	172:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	6	16	theme	initial	822:828	arg1	capacity					849:856	an initial discharge specific capacity	819:856	an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	819:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	3	17	theme	supporting	550:559	arg1	matrix					561:566	the supporting matrix	546:566	the supporting matrix	546:566	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	3	17	theme	supporting	550:559	arg1	film					525:528	The BC film	518:528	The BC film	518:528	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	7	18	theme	proposed	968:975	arg1	configuration					997:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	2	19	theme	thin	345:348	arg1	film					350:353	a flexible polymer-polymer CPE thin film	314:353	a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	314:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	2	20	theme	cellulose	404:412	arg1	framework					419:427	a three-dimensional (3D) bacterial cellulose (BC) framework	369:427	a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	369:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	3	21	theme	high	578:581	arg1	flexibility					583:593	high flexibility	578:593	high flexibility	578:593	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	4	22	theme	1.3 × 10-4S	686:696	arg1	cm-1					698:701	1.3 × 10-4S cm-1	686:701	1.3 × 10-4S cm-1	686:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	1	23	theme	Composite	125:133	arg1	CPE					156:158	CPE	156:158	CPE	156:158	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	23	theme	Composite	125:133	arg1	electrolyte					143:153	Composite polymer electrolyte	125:153	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity	125:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	2	24	theme	bacterial	394:402	arg1	framework					419:427	a three-dimensional (3D) bacterial cellulose (BC) framework	369:427	a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	369:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	0	25	theme	solid	39:43	arg1	electrolytes					63:74	solid composite polymer electrolytes	39:74	solid composite polymer electrolytes for ambient-temperature lithium metal batteries	39:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	7	26	theme	CPE	993:995	arg1	configuration					997:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration	964:1009	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	2	27	theme	polymer-polymer	325:339	arg1	film					350:353	a flexible polymer-polymer CPE thin film	314:353	a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	314:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	4	28	theme	temperature	652:662	arg1	conductivity					670:681	a high room temperature ionic conductivity	640:681	a high room temperature ionic conductivity of 1.3 × 10-4S cm-1	640:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	2	29	theme	CPE	341:343	arg1	film					350:353	a flexible polymer-polymer CPE thin film	314:353	a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	314:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	5	30	theme	stable	747:752	arg1	cycles					754:759	stable cycles	747:759	stable cycles of more than 1200 h	747:779	The Li∣BC-CPE∣Li symmetric cell manifested stable cycles of more than 1200 h.					
35385837	2	31	attach	derived	429:435	arg1	hydrogel					453:460	natural BC hydrogel	442:460	natural BC hydrogel	442:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	2	31	attach	derived	429:435	arg2	framework					419:427	a three-dimensional (3D) bacterial cellulose (BC) framework	369:427	a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	369:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	1	32	theme	electrolyte	143:153	arg1	films					161:165	Composite polymer electrolyte (CPE) films	125:165	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity	125:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	4	33	theme	room	647:650	arg1	temperature					652:662	a high room temperature	640:662	a high room temperature ionic conductivity of 1.3 × 10-4S cm-1	640:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	0	34	theme	polymer	55:61	arg1	electrolytes					63:74	solid composite polymer electrolytes	39:74	solid composite polymer electrolytes for ambient-temperature lithium metal batteries	39:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	6	35	theme	capacity	895:902	arg1	retention					904:912	128.7 mAh g-1with 82.6% discharge capacity retention	861:912	128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	861:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	4	36	theme	cm-1	698:701	arg1	conductivity					670:681	a high room temperature ionic conductivity	640:681	a high room temperature ionic conductivity of 1.3 × 10-4S cm-1	640:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	0	37	theme	composite	45:53	arg1	electrolytes					63:74	solid composite polymer electrolytes	39:74	solid composite polymer electrolytes for ambient-temperature lithium metal batteries	39:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	2	38	theme	thein	479:483	arg1	method					510:515	thein situphoto-polymerization method	479:515	thein situphoto-polymerization method	479:515	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	6	39	theme	discharge	885:893	arg1	retention					904:912	128.7 mAh g-1with 82.6% discharge capacity retention	861:912	128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	861:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	40	theme	BC	450:451	arg1	hydrogel					453:460	natural BC hydrogel	442:460	natural BC hydrogel	442:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	6	41	theme	full	800:803	arg1	cell					805:808	The LCO∣BC-CPE∣Li full cell	782:808	The LCO∣BC-CPE∣Li full cell	782:808	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	1	42	theme	practical	241:249	arg1	application					251:261	the practical application	237:261	the practical application of high-safety solid-state batteries (SSBs)	237:305	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	7	43	theme	cellulose	1095:1103	arg1	biomaterials					1105:1116	cellulose biomaterials	1095:1116	cellulose biomaterials	1095:1116	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	6	44	theme	%	883:883	arg1	retention					904:912	128.7 mAh g-1with 82.6% discharge capacity retention	861:912	128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	861:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	3	45	theme	mechanical	599:608	arg1	strength					610:617	mechanical strength	599:617	mechanical strength	599:617	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	6	46	theme	LCO∣BC-CPE∣Li	786:798	arg1	cell					805:808	The LCO∣BC-CPE∣Li full cell	782:808	The LCO∣BC-CPE∣Li full cell	782:808	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	47	theme	BC	415:416	arg1	framework					419:427	a three-dimensional (3D) bacterial cellulose (BC) framework	369:427	a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	369:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	5	48	theme	Li∣BC-CPE∣Li	708:719	arg1	cell					731:734	The Li∣BC-CPE∣Li symmetric cell	704:734	The Li∣BC-CPE∣Li symmetric cell	704:734	The Li∣BC-CPE∣Li symmetric cell manifested stable cycles of more than 1200 h.					
35385837	6	49	theme	82.6	879:882	arg1	%					883:883	%	883:883	%	883:883	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	50	theme	three-dimensional	371:387	arg1	framework					419:427	a three-dimensional (3D) bacterial cellulose (BC) framework	369:427	a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel	369:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	3	51	theme	BC	522:523	arg1	matrix					561:566	the supporting matrix	546:566	the supporting matrix	546:566	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	3	51	theme	BC	522:523	arg1	film					525:528	The BC film	518:528	The BC film	518:528	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	3	52	used	utilized	534:541	arg2	film					525:528	The BC film	518:528	The BC film	518:528	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	3	52	used	utilized	534:541	arg2	matrix					561:566	the supporting matrix	546:566	the supporting matrix	546:566	The BC film was utilized as the supporting matrix to ensure high flexibility and mechanical strength.					
35385837	5	53	theme	symmetric	721:729	arg1	cell					731:734	The Li∣BC-CPE∣Li symmetric cell	704:734	The Li∣BC-CPE∣Li symmetric cell	704:734	The Li∣BC-CPE∣Li symmetric cell manifested stable cycles of more than 1200 h.					
35385837	6	54	theme	g-1with	871:877	arg1	retention					904:912	128.7 mAh g-1with 82.6% discharge capacity retention	861:912	128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles	861:929	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	7	55	theme	environmental	1058:1070	arg1	SSBs					1072:1075	environmental SSBs	1058:1075	environmental SSBs	1058:1075	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	1	56	theme	polymer	135:141	arg1	CPE					156:158	CPE	156:158	CPE	156:158	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	56	theme	polymer	135:141	arg1	electrolyte					143:153	Composite polymer electrolyte	125:153	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity	125:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	0	57	theme	lithium	100:106	arg1	batteries					114:122	ambient-temperature lithium metal batteries	80:122	ambient-temperature lithium metal batteries	80:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	4	58	theme	ionic	664:668	arg1	conductivity					670:681	a high room temperature ionic conductivity	640:681	a high room temperature ionic conductivity of 1.3 × 10-4S cm-1	640:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	7	59	from	abundant	1122:1129	arg1	nature					1134:1139	nature	1134:1139	nature	1134:1139	The proposed polymer-polymer CPE configuration represents a promising route for manufacturing environmental SSBs, especially since cellulose biomaterials are abundant in nature.					
35385837	4	60	theme	high	642:645	arg1	temperature					652:662	a high room temperature	640:662	a high room temperature ionic conductivity of 1.3 × 10-4S cm-1	640:701	The BC-CPE attained a high room temperature ionic conductivity of 1.3 × 10-4S cm-1.					
35385837	1	61	theme	high-safety	266:276	arg1	SSBs					301:304	SSBs	301:304	SSBs	301:304	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	61	theme	high-safety	266:276	arg1	batteries					290:298	high-safety solid-state batteries	266:298	high-safety solid-state batteries (SSBs)	266:305	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	0	62	theme	ambient-temperature	80:98	arg1	batteries					114:122	ambient-temperature lithium metal batteries	80:122	ambient-temperature lithium metal batteries	80:122	Bacteria cellulose framework-supported solid composite polymer electrolytes for ambient-temperature lithium metal batteries.					
35385837	6	63	theme	room	946:949	arg1	temperature					951:961	room temperature	946:961	room temperature	946:961	The LCO∣BC-CPE∣Li full cell attained an initial discharge specific capacity of 128.7 mAh g-1with 82.6% discharge capacity retention after 150 cycles at 0.2 C under room temperature.					
35385837	2	64	theme	natural	442:448	arg1	hydrogel					453:460	natural BC hydrogel	442:460	natural BC hydrogel	442:460	Here, a flexible polymer-polymer CPE thin film reinforced by a three-dimensional (3D) bacterial cellulose (BC) framework derived from natural BC hydrogel was prepared via thein situphoto-polymerization method.					
35385837	1	65	theme	high	172:175	arg1	temperature					182:192	high room temperature	172:192	high room temperature ionic conductivity	172:211	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	66	theme	solid-state	278:288	arg1	SSBs					301:304	SSBs	301:304	SSBs	301:304	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
35385837	1	66	theme	solid-state	278:288	arg1	batteries					290:298	high-safety solid-state batteries	266:298	high-safety solid-state batteries (SSBs)	266:305	Composite polymer electrolyte (CPE) films with high room temperature ionic conductivity are urgently needed for the practical application of high-safety solid-state batteries (SSBs).					
36989651	1	0	theme	food	208:211	arg1	systems					223:229	food packaging systems	208:229	food packaging systems containing essential oils (EOs)	208:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	3	1	theme	effective	376:384	arg1	encapsulation					386:398	effective encapsulation	376:398	effective encapsulation of EOs	376:405	Therefore, effective encapsulation of EOs is demanded for their protection and controlled release.					
36989651	1	2	theme	packaging	213:221	arg1	systems					223:229	food packaging systems	208:229	food packaging systems containing essential oils (EOs)	208:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	0	3	theme	release	132:138	arg1	kinetics					140:147	release kinetics	132:147	release kinetics	132:147	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	4	4	theme	globulus	525:532	arg1	oil					544:546	Eucalyptus globulus essential oil	514:546	Eucalyptus globulus essential oil	514:546	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	2	5	theme	EOs	332:334	arg1	instability					317:327	the instability	313:327	the instability of EOs	313:334	However, the instability of EOs restricts their application.					
36989651	3	6	theme	EOs	403:405	arg1	encapsulation					386:398	effective encapsulation	376:398	effective encapsulation of EOs	376:405	Therefore, effective encapsulation of EOs is demanded for their protection and controlled release.					
36989651	4	7	theme	Eucalyptus	514:523	arg1	oil					544:546	Eucalyptus globulus essential oil	514:546	Eucalyptus globulus essential oil	514:546	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	1	8	theme	systems	223:229	arg1	Development					193:203	Development	193:203	Development of food packaging systems containing essential oils (EOs)	193:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	5	9	theme	complexes	800:808	arg1	%					779:779	40%	777:779	40% (w/w) of inclusion complexes	777:808	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	5	9	theme	complexes	800:808	arg1	complexes					800:808	inclusion complexes	790:808	inclusion complexes	790:808	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	5	9	theme	complexes	800:808	arg1	w/w					782:784	w/w	782:784	w/w	782:784	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	7	10	theme	EOs	1185:1187	arg1	availability					1169:1180	the availability	1165:1180	the availability of EOs	1165:1187	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	7	11	theme	electrospun	1110:1120	arg1	nanofibers					1122:1131	cyclodextrin and electrospun nanofibers	1093:1131	nanofibers	1122:1131	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	3	12	theme	controlled	444:453	arg1	release					455:461	controlled release	444:461	controlled release	444:461	Therefore, effective encapsulation of EOs is demanded for their protection and controlled release.					
36989651	4	13	theme	nanofibrous	725:735	arg1	film					737:740	nanofibrous film	725:740	nanofibrous film	725:740	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	0	14	theme	polyvinyl	12:20	arg1	alcohol/chitosan					22:37	Electrospun polyvinyl alcohol/chitosan	0:37	Electrospun polyvinyl alcohol/chitosan	0:37	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	4	15	theme	essential	534:542	arg1	oil					544:546	Eucalyptus globulus essential oil	514:546	Eucalyptus globulus essential oil	514:546	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	6	16	from	℃	1041:1041	arg1	6 days					1028:1033	6 days	1028:1033	6 days at 25 ℃	1028:1041	Moreover, this film could extend the shelf life of strawberries to 6 days at 25 ℃.					
36989651	7	17	theme	produced	1198:1205	arg1	promising					1215:1223	promising	1215:1223	promising	1215:1223	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	7	17	theme	produced	1198:1205	arg1	film					1207:1210	the produced film	1194:1210	the produced film	1194:1210	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	1	18	theme	essential	242:250	arg1	EOs					258:260	EOs	258:260	EOs	258:260	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	1	18	theme	essential	242:250	arg1	oils					252:255	essential oils	242:255	essential oils (EOs)	242:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	0	19	theme	Electrospun	0:10	arg1	alcohol/chitosan					22:37	Electrospun polyvinyl alcohol/chitosan	0:37	Electrospun polyvinyl alcohol/chitosan	0:37	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	4	20	theme	polyvinyl	663:671	arg1	alcohol					673:679	polyvinyl alcohol	663:679	polyvinyl alcohol	663:679	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	4	21	theme	inclusion	611:619	arg1	complex					621:627	an inclusion complex	608:627	an inclusion complex	608:627	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	0	22	theme	strawberry	168:177	arg1	preservation					179:190	strawberry preservation	168:190	strawberry preservation	168:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	5	23	theme	1,8-cineole	880:890	arg1	release					869:875	the release	865:875	the release of 1,8-cineole from the film	865:904	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	4	24	from	component	501:509	arg1	oil					544:546	Eucalyptus globulus essential oil	514:546	Eucalyptus globulus essential oil	514:546	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	4	25	theme	major	495:499	arg1	1,8-cineole					478:488	1,8-cineole	478:488	1,8-cineole	478:488	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	4	25	theme	major	495:499	arg1	component					501:509	the major component	491:509	the major component in Eucalyptus globulus essential oil	491:546	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	0	26	dep	complexes	103:111	arg1	Characterization					114:129	Characterization	114:129	Characterization	114:129	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	26	dep	complexes	103:111	arg1	kinetics					140:147	release kinetics	132:147	release kinetics	132:147	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	26	dep	complexes	103:111	arg1	complexes					103:111	1,8-cineole/cyclodextrin inclusion complexes	68:111	1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation	68:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	26	dep	complexes	103:111	arg1	application					153:163	application	153:163	application in strawberry preservation	153:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	4	27	theme	composite	694:702	arg1	polymer					704:710	chitosan composite polymer	685:710	chitosan composite polymer	685:710	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	5	28	theme	mechanical	838:847	arg1	properties					849:858	enhanced barrier and mechanical properties	817:858	properties	849:858	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	0	29	from	Characterization	114:129	arg1	preservation					179:190	strawberry preservation	168:190	strawberry preservation	168:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	5	30	with	film	767:770	arg1	%					779:779	40%	777:779	40% (w/w) of inclusion complexes	777:808	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	5	30	with	film	767:770	arg1	complexes					800:808	inclusion complexes	790:808	inclusion complexes	790:808	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	5	30	with	film	767:770	arg1	w/w					782:784	w/w	782:784	w/w	782:784	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	6	31	theme	shelf	998:1002	arg1	life					1004:1007	the shelf life	994:1007	the shelf life of strawberries to 6 days at 25 ℃	994:1041	Moreover, this film could extend the shelf life of strawberries to 6 days at 25 ℃.					
36989651	7	32	theme	cyclodextrin	1093:1104	arg1	nanofibers					1122:1131	cyclodextrin and electrospun nanofibers	1093:1131	nanofibers	1122:1131	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	1	33	contain	containing	231:240	arg1	systems					223:229	food packaging systems	208:229	food packaging systems containing essential oils (EOs)	208:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	1	33	contain	containing	231:240	arg2	oils					252:255	essential oils	242:255	essential oils (EOs)	242:261	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	1	33	contain	containing	231:240	arg2	EOs					258:260	EOs	258:260	EOs	258:260	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	5	34	from	film	901:904	arg1	release					869:875	the release	865:875	the release of 1,8-cineole from the film	865:904	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	0	35	theme	inclusion	93:101	arg1	Characterization					114:129	Characterization	114:129	Characterization	114:129	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	35	theme	inclusion	93:101	arg1	complexes					103:111	1,8-cineole/cyclodextrin inclusion complexes	68:111	1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation	68:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	35	theme	inclusion	93:101	arg1	application					153:163	application	153:163	application in strawberry preservation	153:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	6	36	theme	strawberries	1012:1023	arg1	life					1004:1007	the shelf life	994:1007	the shelf life of strawberries to 6 days at 25 ℃	994:1041	Moreover, this film could extend the shelf life of strawberries to 6 days at 25 ℃.					
36989651	0	37	theme	1,8-cineole/cyclodextrin	68:91	arg1	Characterization					114:129	Characterization	114:129	Characterization	114:129	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	37	theme	1,8-cineole/cyclodextrin	68:91	arg1	complexes					103:111	1,8-cineole/cyclodextrin inclusion complexes	68:111	1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation	68:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	0	37	theme	1,8-cineole/cyclodextrin	68:91	arg1	application					153:163	application	153:163	application in strawberry preservation	153:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	7	38	theme	EOs	1086:1088	arg1	encapsulation					1069:1081	dual encapsulation	1064:1081	dual encapsulation of EOs by cyclodextrin and electrospun nanofibers	1064:1131	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	0	39	from	application	153:163	arg1	preservation					179:190	strawberry preservation	168:190	strawberry preservation	168:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	7	40	theme	ideal	1139:1143	arg1	work					1049:1052	This work	1044:1052	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers	1044:1131	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	7	40	theme	ideal	1139:1143	arg1	strategy					1145:1152	an ideal strategy	1136:1152	an ideal strategy to improve the availability of EOs	1136:1187	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	7	41	theme	dual	1064:1067	arg1	encapsulation					1069:1081	dual encapsulation	1064:1081	dual encapsulation of EOs by cyclodextrin and electrospun nanofibers	1064:1131	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36989651	0	42	dep	nanofibers	39:48	arg1	incorporated					50:61	incorporated	50:61	nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation	39:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	5	43	theme	inclusion	790:798	arg1	complexes					800:808	inclusion complexes	790:808	inclusion complexes	790:808	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	0	44	from	kinetics	140:147	arg1	preservation					179:190	strawberry preservation	168:190	strawberry preservation	168:190	Electrospun polyvinyl alcohol/chitosan nanofibers incorporated with 1,8-cineole/cyclodextrin inclusion complexes: Characterization, release kinetics and application in strawberry preservation.					
36989651	1	45	theme	increased	274:282	arg1	attention					284:292	increased attention	274:292	increased attention	274:292	Development of food packaging systems containing essential oils (EOs) has gained increased attention recently.					
36989651	4	46	theme	chitosan	685:692	arg1	polymer					704:710	chitosan composite polymer	685:710	chitosan composite polymer	685:710	In this work, 1,8-cineole, the major component in Eucalyptus globulus essential oil, was encapsulated into hydroxypropyl-β-cyclodextrin to form an inclusion complex, which was then incorporated into polyvinyl alcohol and chitosan composite polymer to fabricate nanofibrous film via electrospinning.					
36989651	5	47	theme	enhanced	817:824	arg1	barrier					826:832	enhanced barrier and mechanical properties	817:858	barrier	826:832	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	5	48	theme	non-Fick	941:948	arg1	diffusion					950:958	the non-Fick diffusion	937:958	the non-Fick diffusion	937:958	The film with 40% (w/w) of inclusion complexes showed enhanced barrier and mechanical properties, and the release of 1,8-cineole from the film was sustained and dominated by the non-Fick diffusion.					
36989651	7	49	theme	food	1229:1232	arg1	preservation					1234:1245	food preservation	1229:1245	food preservation	1229:1245	This work suggested dual encapsulation of EOs by cyclodextrin and electrospun nanofibers is an ideal strategy to improve the availability of EOs, and the produced film is promising for food preservation.					
36592805	3	0	theme	fixed-bed	693:701	arg1	assays					703:708	batch and fixed-bed assays	683:708	batch and fixed-bed assays	683:708	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	5	1	theme	physical	848:855	arg1	interlacements					857:870	physical interlacements	848:870	physical interlacements	848:870	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	0	2	from	water	154:158	arg1	features					107:114	the aerogel features	95:114	the aerogel features	95:114	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	0	2	from	water	154:158	arg1	adsorption					124:133	the adsorption	120:133	the adsorption of contaminants in water	120:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	4	3	theme	zeta	800:803	arg1	potential					805:813	zeta potential	800:813	zeta potential	800:813	The CS@CNC-HTA beads properties were assessed by FTIR, XRD, SEM, XPS, Micro-CT, WCA, and zeta potential.					
36592805	5	4	theme	open	981:984	arg1	space					991:995	open pore space	981:995	open pore space	981:995	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	8	5	theme	Theoretical	1497:1507	arg1	calculations					1509:1520	Theoretical calculations	1497:1520	Theoretical calculations	1497:1520	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	7	6	theme	sildenafil	1347:1356	arg1	citrate					1358:1364	sildenafil citrate	1347:1364	sildenafil citrate	1347:1364	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	3	7	theme	batch	683:687	arg1	assays					703:708	batch and fixed-bed assays	683:708	batch and fixed-bed assays	683:708	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	7	8	with	experiments	1423:1433	arg1	times					1451:1455	exhaustion times	1440:1455	exhaustion times of 890, 300, and 470 min, respectively	1440:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	3	9	theme	hydrophobized	509:521	arg1	composite					541:549	hydrophobized tannic acid (HTA) composite	509:549	hydrophobized tannic acid (HTA) composite	509:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	2	10	theme	few	288:290	arg1	studies					292:298	few studies	288:298	few studies	288:298	However, few studies have reported the application of hydrophobic aerogels as adsorbent for organic contaminants dissolved in water.					
36592805	5	11	theme	high	942:945	arg1	porosity					947:954	high porosity	942:954	high porosity (98.6%)	942:962	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	11	theme	high	942:945	arg1	%					961:961	98.6%	957:961	98.6%	957:961	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	0	12	from	contaminants	138:149	arg1	water					154:158	water	154:158	water	154:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	6	13	theme	CNC-HTA	1049:1055	arg1	beads					1057:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	14	theme	@	1048:1048	arg1	beads					1057:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	5	15	theme	@	922:922	arg1	beads					931:935	CS@CNC-HTA beads	920:935	CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°)	920:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	7	16	theme	@	1312:1312	arg1	beads					1321:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	0	17	theme	aerogel	99:105	arg1	features					107:114	the aerogel features	95:114	the aerogel features	95:114	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	3	18	theme	acid	530:533	arg1	composite					541:549	hydrophobized tannic acid (HTA) composite	509:549	hydrophobized tannic acid (HTA) composite	509:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	19	theme	chitosan	445:452	arg1	beads					459:463	novel highly hydrophobic chitosan (CS) beads	420:463	novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite	420:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	6	20	theme	86	1245:1246	arg1	capacities					1231:1240	adsorption capacities	1220:1240	adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1	1220:1285	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	21	theme	blue	1153:1156	arg1	citrate					1134:1140	the pharmaceutical sildenafil citrate	1104:1140	the pharmaceutical sildenafil citrate	1104:1140	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	21	theme	blue	1153:1156	arg1	dye					1161:1163	the basic blue 26 dye	1143:1163	the basic blue 26 dye	1143:1163	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	5	22	theme	beads	931:935	arg1	formation					907:915	the formation	903:915	the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°)	903:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	1	23	theme	Hydrophobic	161:171	arg1	aerogels					182:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	1	23	theme	Hydrophobic	161:171	arg1	adsorbents					205:214	promising adsorbents	195:214	promising adsorbents for immiscible contaminants such as oils and organic solvents	195:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	6	24	theme	basic	1147:1151	arg1	citrate					1134:1140	the pharmaceutical sildenafil citrate	1104:1140	the pharmaceutical sildenafil citrate	1104:1140	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	24	theme	basic	1147:1151	arg1	dye					1161:1163	the basic blue 26 dye	1143:1163	the basic blue 26 dye	1143:1163	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	4	25	theme	CNC-HTA	718:724	arg1	beads					726:730	The CS@CNC-HTA beads	711:730	The CS@CNC-HTA beads properties	711:741	The CS@CNC-HTA beads properties were assessed by FTIR, XRD, SEM, XPS, Micro-CT, WCA, and zeta potential.					
36592805	8	26	theme	adsorption	1526:1535	arg1	assays					1537:1542	adsorption assays	1526:1542	adsorption assays	1526:1542	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	1	27	theme	chitosan	173:180	arg1	aerogels					182:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	1	27	theme	chitosan	173:180	arg1	adsorbents					205:214	promising adsorbents	195:214	promising adsorbents for immiscible contaminants such as oils and organic solvents	195:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	7	28	theme	890	1460:1462	arg1	times					1451:1455	exhaustion times	1440:1455	exhaustion times of 890, 300, and 470 min, respectively	1440:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	3	29	dep	novel	420:424	arg1	hydrophobic					433:443	hydrophobic	433:443	hydrophobic	433:443	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	4	30	theme	@	717:717	arg1	beads					726:730	The CS@CNC-HTA beads	711:730	The CS@CNC-HTA beads properties	711:741	The CS@CNC-HTA beads properties were assessed by FTIR, XRD, SEM, XPS, Micro-CT, WCA, and zeta potential.					
36592805	5	31	theme	Supramolecular	816:829	arg1	interactions					831:842	Supramolecular interactions	816:842	Supramolecular interactions	816:842	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	6	32	theme	390	1270:1272	arg1	capacities					1231:1240	adsorption capacities	1220:1240	adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1	1220:1285	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	33	theme	CS	1046:1047	arg1	beads					1057:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads	1038:1061	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	7	34	theme	470 min	1474:1480	arg1	times					1451:1455	exhaustion times	1440:1455	exhaustion times of 890, 300, and 470 min, respectively	1440:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	0	35	theme	aerogels	20:27	arg1	Hydrophobization					0:15	Hydrophobization	0:15	Hydrophobization of aerogels	0:27	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	6	36	theme	best	1074:1077	arg1	performance					1079:1089	the best performance	1070:1089	the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride	1070:1208	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	5	37	theme	CNC-HTA	923:929	arg1	beads					931:935	CS@CNC-HTA beads	920:935	CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°)	920:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	38	theme	pore	986:989	arg1	space					991:995	open pore space	981:995	open pore space	981:995	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	7	39	theme	300	1465:1467	arg1	times					1451:1455	exhaustion times	1440:1455	exhaustion times of 890, 300, and 470 min, respectively	1440:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	1	40	theme	promising	195:203	arg1	aerogels					182:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels	161:189	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	1	40	theme	promising	195:203	arg1	adsorbents					205:214	promising adsorbents	195:214	promising adsorbents for immiscible contaminants such as oils and organic solvents	195:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	3	41	attach	remove	640:645	arg2	adsorbent					627:635	adsorbent	627:635	adsorbent	627:635	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	41	attach	remove	640:645	arg1	water					674:678	water	674:678	water	674:678	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	4	42	dep	beads	726:730	arg1	properties					732:741	properties	732:741	The CS@CNC-HTA beads properties	711:741	The CS@CNC-HTA beads properties were assessed by FTIR, XRD, SEM, XPS, Micro-CT, WCA, and zeta potential.					
36592805	6	43	theme	adsorption	1220:1229	arg1	capacities					1231:1240	adsorption capacities	1220:1240	adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1	1220:1285	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	5	44	theme	space	991:995	arg1	porosity					947:954	high porosity	942:954	high porosity (98.6%)	942:962	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	44	theme	space	991:995	arg1	volume					971:976	great volume	965:976	great volume of open pore space (10.16 mm3)	965:1007	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	44	theme	space	991:995	arg1	hydrophobicity					1013:1026	hydrophobicity	1013:1026	hydrophobicity (121.8°)	1013:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	44	theme	space	991:995	arg1	%					961:961	98.6%	957:961	98.6%	957:961	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	44	theme	space	991:995	arg1	121.8°					1029:1034	121.8°	1029:1034	121.8°	1029:1034	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	44	theme	space	991:995	arg1	10.16 mm3					998:1006	10.16 mm3	998:1006	10.16 mm3	998:1006	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	3	45	theme	novel	420:424	arg1	chitosan					445:452	novel highly hydrophobic chitosan	420:452	novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite	420:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	45	theme	novel	420:424	arg1	CS					455:456	CS	455:456	CS	455:456	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	5	46	with	beads	931:935	arg1	porosity					947:954	high porosity	942:954	high porosity (98.6%)	942:962	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	46	with	beads	931:935	arg1	volume					971:976	great volume	965:976	great volume of open pore space (10.16 mm3)	965:1007	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	46	with	beads	931:935	arg1	hydrophobicity					1013:1026	hydrophobicity	1013:1026	hydrophobicity (121.8°)	1013:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	46	with	beads	931:935	arg1	%					961:961	98.6%	957:961	98.6%	957:961	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	46	with	beads	931:935	arg1	121.8°					1029:1034	121.8°	1029:1034	121.8°	1029:1034	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	46	with	beads	931:935	arg1	10.16 mm3					998:1006	10.16 mm3	998:1006	10.16 mm3	998:1006	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	3	47	contain	containing	465:474	arg2	CNC					500:502	CNC	500:502	CNC	500:502	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	47	contain	containing	465:474	arg1	beads					459:463	novel highly hydrophobic chitosan (CS) beads	420:463	novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite	420:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	47	contain	containing	465:474	arg2	composite					541:549	hydrophobized tannic acid (HTA) composite	509:549	hydrophobized tannic acid (HTA) composite	509:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	47	contain	containing	465:474	arg2	nanocrystals					486:497	cellulose nanocrystals	476:497	cellulose nanocrystals (CNC)	476:503	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	48	theme	CNC-HTA	587:593	arg1	content					595:601	CNC-HTA content	587:601	CNC-HTA content	587:601	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	7	49	theme	exhaustion	1440:1449	arg1	times					1451:1455	exhaustion times	1440:1455	exhaustion times of 890, 300, and 470 min, respectively	1440:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	0	50	theme	contaminants	138:149	arg1	features					107:114	the aerogel features	95:114	the aerogel features	95:114	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	0	50	theme	contaminants	138:149	arg1	adsorption					124:133	the adsorption	120:133	the adsorption of contaminants in water	120:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	6	51	theme	375	1255:1257	arg1	capacities					1231:1240	adsorption capacities	1220:1240	adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1	1220:1285	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	3	52	theme	different	570:578	arg1	CS					580:581	different CS	570:581	different CS	570:581	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	8	53	theme	attractive	1567:1576	arg1	pyridinium-π					1595:1606	pyridinium-π	1595:1606	pyridinium-π	1595:1606	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	8	53	theme	attractive	1567:1576	arg1	interactions					1578:1589	the main attractive interactions	1558:1589	the main attractive interactions	1558:1589	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	2	54	theme	aerogels	345:352	arg1	application					318:328	the application	314:328	the application of hydrophobic aerogels	314:352	However, few studies have reported the application of hydrophobic aerogels as adsorbent for organic contaminants dissolved in water.					
36592805	7	55	theme	fixed-bed	1413:1421	arg1	experiments					1423:1433	fixed-bed experiments	1413:1433	fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively	1413:1494	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	5	56	theme	great	965:969	arg1	volume					971:976	great volume	965:976	great volume of open pore space (10.16 mm3)	965:1007	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	5	56	theme	great	965:969	arg1	10.16 mm3					998:1006	10.16 mm3	998:1006	10.16 mm3	998:1006	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	6	57	theme	pharmaceutical	1108:1121	arg1	citrate					1134:1140	the pharmaceutical sildenafil citrate	1104:1140	the pharmaceutical sildenafil citrate	1104:1140	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	57	theme	pharmaceutical	1108:1121	arg1	dye					1161:1163	the basic blue 26 dye	1143:1163	the basic blue 26 dye	1143:1163	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	8	58	theme	main	1562:1565	arg1	pyridinium-π					1595:1606	pyridinium-π	1595:1606	pyridinium-π	1595:1606	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	8	58	theme	main	1562:1565	arg1	interactions					1578:1589	the main attractive interactions	1558:1589	the main attractive interactions	1558:1589	Theoretical calculations and adsorption assays indicate that the main attractive interactions are pyridinium-π, π-π, electrostatic and hydrophobic.					
36592805	2	59	theme	hydrophobic	333:343	arg1	aerogels					345:352	hydrophobic aerogels	333:352	hydrophobic aerogels	333:352	However, few studies have reported the application of hydrophobic aerogels as adsorbent for organic contaminants dissolved in water.					
36592805	6	60	theme	cetylpyridinium	1185:1199	arg1	chloride					1201:1208	the surfactant cetylpyridinium chloride	1170:1208	the surfactant cetylpyridinium chloride	1170:1208	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	7	61	theme	CS	1310:1311	arg1	beads					1321:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	7	62	theme	CNC‒HTA	1313:1319	arg1	beads					1321:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads	1302:1325	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	6	63	dep	86	1245:1246	arg1	mg.g-1					1280:1285	mg.g-1	1280:1285	mg.g-1	1280:1285	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	3	64	theme	cellulose	476:484	arg1	CNC					500:502	CNC	500:502	CNC	500:502	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	64	theme	cellulose	476:484	arg1	nanocrystals					486:497	cellulose nanocrystals	476:497	cellulose nanocrystals (CNC)	476:503	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	0	65	from	adsorption	124:133	arg1	water					154:158	water	154:158	water	154:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	6	66	theme	surfactant	1174:1183	arg1	chloride					1201:1208	the surfactant cetylpyridinium chloride	1170:1208	the surfactant cetylpyridinium chloride	1170:1208	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	3	67	theme	emerging	647:654	arg1	contaminants					656:667	emerging contaminants	647:667	emerging contaminants	647:667	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	5	68	theme	CS	920:921	arg1	beads					931:935	CS@CNC-HTA beads	920:935	CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°)	920:1035	Supramolecular interactions and physical interlacements between CS and CNC-HTA enabled the formation of CS@CNC-HTA beads with high porosity (98.6%), great volume of open pore space (10.16 mm3) and hydrophobicity (121.8°).					
36592805	3	69	theme	tannic	523:528	arg1	HTA					536:538	HTA	536:538	HTA	536:538	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	3	69	theme	tannic	523:528	arg1	acid					530:533	tannic acid	523:533	hydrophobized tannic acid (HTA) composite	509:549	Herein, novel highly hydrophobic chitosan (CS) beads containing cellulose nanocrystals (CNC) and hydrophobized tannic acid (HTA) composite were prepared with different CS and CNC-HTA content to achieve an optimized adsorbent to remove emerging contaminants from water in batch and fixed-bed assays.					
36592805	4	70	theme	CS	715:716	arg1	beads					726:730	The CS@CNC-HTA beads	711:730	The CS@CNC-HTA beads properties	711:741	The CS@CNC-HTA beads properties were assessed by FTIR, XRD, SEM, XPS, Micro-CT, WCA, and zeta potential.					
36592805	0	71	theme	tannic	66:71	arg1	acid					73:76	tannic acid	66:76	tannic acid	66:76	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	0	72	from	Improvements	79:90	arg1	features					107:114	the aerogel features	95:114	the aerogel features	95:114	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	0	72	from	Improvements	79:90	arg1	adsorption					124:133	the adsorption	120:133	the adsorption of contaminants in water	120:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
36592805	6	73	theme	sildenafil	1123:1132	arg1	citrate					1134:1140	the pharmaceutical sildenafil citrate	1104:1140	the pharmaceutical sildenafil citrate	1104:1140	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	6	73	theme	sildenafil	1123:1132	arg1	dye					1161:1163	the basic blue 26 dye	1143:1163	the basic blue 26 dye	1143:1163	The 1:1 CS@CNC-HTA beads showed the best performance for removing the pharmaceutical sildenafil citrate, the basic blue 26 dye, and the surfactant cetylpyridinium chloride, reaching adsorption capacities of 86 (73%), 375 (84%), and 390 (90%) mg.g-1, respectively.					
36592805	2	74	theme	organic	371:377	arg1	contaminants					379:390	organic contaminants	371:390	organic contaminants dissolved in water	371:409	However, few studies have reported the application of hydrophobic aerogels as adsorbent for organic contaminants dissolved in water.					
36592805	1	75	theme	organic	261:267	arg1	solvents					269:276	organic solvents	261:276	organic solvents	261:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	7	76	theme	cetylpyridinium	1385:1399	arg1	chloride					1401:1408	cetylpyridinium chloride	1385:1408	cetylpyridinium chloride	1385:1408	The 1:1 CS@CNC‒HTA beads efficiently removed sildenafil citrate, basic blue 26 and cetylpyridinium chloride in fixed-bed experiments with exhaustion times of 890, 300, and 470 min, respectively.					
36592805	1	77	theme	immiscible	220:229	arg1	contaminants					231:242	immiscible contaminants	220:242	immiscible contaminants such as oils and organic solvents	220:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	1	77	theme	immiscible	220:229	arg1	oils					252:255	oils	252:255	oils	252:255	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	1	77	theme	immiscible	220:229	arg1	solvents					269:276	organic solvents	261:276	organic solvents	261:276	Hydrophobic chitosan aerogels are promising adsorbents for immiscible contaminants such as oils and organic solvents.					
36592805	0	78	from	features	107:114	arg1	water					154:158	water	154:158	water	154:158	Hydrophobization of aerogels based on chitosan, nanocellulose and tannic acid: Improvements on the aerogel features and the adsorption of contaminants in water.					
37149285	6	0	theme	native	878:883	arg1	n=16					920:923	n=16	920:923	n=16	920:923	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	0	theme	native	878:883	arg1	samples					911:917	native and HMO-spiked human milk samples	878:917	native and HMO-spiked human milk samples (n=16 each)	878:929	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	11	1	theme	CONCLUSION	1913:1922	arg1	methods					1929:1935	CONCLUSION AOAC methods 984.22 and 2006.06	1913:1954	CONCLUSION AOAC methods 984.22 and 2006.06	1913:1954	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	12	2	theme	enzymatic	2060:2068	arg1	methods					2070:2076	other enzymatic methods	2054:2076	other enzymatic methods	2054:2076	HMOs influence other enzymatic methods, as well as infrared analysis, which leads to an overestimate of energy values.					
37149285	7	3	theme	milk	1170:1173	arg1	n=20					1184:1187	n=20	1184:1187	n=20	1184:1187	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	7	3	theme	milk	1170:1173	arg1	samples					1175:1181	human milk samples	1164:1181	human milk samples (n=20)	1164:1188	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	12	4	theme	energy	2143:2148	arg1	values					2150:2155	energy values	2143:2155	energy values	2143:2155	HMOs influence other enzymatic methods, as well as infrared analysis, which leads to an overestimate of energy values.					
37149285	6	5	with	assay	1045:1049	arg1	mass-spectroscopy					1097:1113	mass-spectroscopy	1097:1113	mass-spectroscopy (UPLC-MS)	1097:1123	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	5	with	assay	1045:1049	arg1	UPLC-MS					1116:1122	UPLC-MS	1116:1122	UPLC-MS	1116:1122	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	8	6	from	different	1492:1500	arg1	lactose					1505:1511	lactose	1505:1511	lactose using AOAC 2006.06 and UPLC-MS	1505:1542	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	7	theme	%	1625:1625	arg1	CI					1626:1627	mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4	1595:1638	CI	1626:1627	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	7	theme	%	1625:1625	arg1	BioVision					1584:1592	BioVision	1584:1592	BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005)	1584:1650	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	2	8	theme	bovine	379:384	arg1	industry					392:399	the bovine dairy industry	375:399	the bovine dairy industry	375:399	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	2	9	theme	human	282:286	arg1	milk					288:291	human milk	282:291	human milk	282:291	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	7	10	from	2006.06	1372:1378	arg1	milk					1263:1266	bovine milk	1256:1266	bovine milk	1256:1266	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	7	11	theme	refractive	1335:1344	arg1	index					1346:1350	refractive index	1335:1350	refractive index	1335:1350	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	8	12	from	lactose	1505:1511	arg1	different					1492:1500	different	1492:1500	different	1492:1500	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	1	13	theme	analytical	192:201	arg1	methods					203:209	valid analytical methods	186:209	valid analytical methods	186:209	BACKGROUND Understanding how human milk impacts growth requires valid analytical methods for quantifying composition.					
37149285	10	14	dep	>	1893:1893	arg1	<					1903:1903	p < 0.001	1901:1909	p < 0.001	1901:1909	Only AOAC methods 984.22 and 2006.06 for measuring lactose were very highly correlated (r > 0.90, p < 0.001).					
37149285	0	15	theme	methods	113:119	arg1	comparison					99:108	comparison	99:108	comparison of methods	99:119	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	0	15	theme	methods	113:119	arg1	lactose					49:55	lactose	49:55	lactose	49:55	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	0	15	theme	methods	113:119	arg1	carbohydrates					67:79	total carbohydrates	61:79	total carbohydrates	61:79	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	2	16	theme	predominant	299:309	arg1	source					311:316	a predominant source	297:316	a predominant source of energy	297:326	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	2	16	theme	predominant	299:309	arg1	Lactose					240:246	Lactose	240:246	Lactose	240:246	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	7	17	theme	high-performance	1292:1307	arg1	chromatography					1316:1329	high-performance liquid chromatography	1292:1329	high-performance liquid chromatography	1292:1329	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	9	18	theme	<	1793:1793	arg1	p					1791:1791	p < 0.001	1791:1799	p < 0.001	1791:1799	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	9	18	theme	<	1793:1793	arg1	0.6					1786:1788	0.6	1786:1788	0.6	1786:1788	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	3	19	theme	lactose	569:575	arg1	unit					577:580	a terminal lactose unit	558:580	a terminal lactose unit that may influence analytical methods	558:618	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	6	20	theme	milk	906:909	arg1	n=16					920:923	n=16	920:923	n=16	920:923	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	20	theme	milk	906:909	arg1	samples					911:917	native and HMO-spiked human milk samples	878:917	native and HMO-spiked human milk samples (n=16 each)	878:929	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	12	21	theme	infrared	2090:2097	arg1	analysis					2099:2106	infrared analysis	2090:2106	infrared analysis	2090:2106	HMOs influence other enzymatic methods, as well as infrared analysis, which leads to an overestimate of energy values.					
37149285	6	22	theme	HMO-spiked	889:898	arg1	n=16					920:923	n=16	920:923	n=16	920:923	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	22	theme	HMO-spiked	889:898	arg1	samples					911:917	native and HMO-spiked human milk samples	878:917	native and HMO-spiked human milk samples (n=16 each)	878:929	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	0	23	from	comparison	99:108	arg1	milk					90:93	human milk	84:93	human milk	84:93	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	7	24	theme	AOAC	1269:1272	arg1	984.22					1274:1279	AOAC 984.22	1269:1279	AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection	1269:1360	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	4	25	theme	common	694:699	arg1	methods					712:718	common analytical methods	694:718	common analytical methods for measuring carbohydrates in human milk	694:760	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	7	26	theme	human	1164:1168	arg1	n=20					1184:1187	n=20	1184:1187	n=20	1184:1187	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	7	26	theme	human	1164:1168	arg1	samples					1175:1181	human milk samples	1164:1181	human milk samples (n=20)	1164:1188	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	9	27	dep	0.6	1786:1788	arg1	to					1783:1784	to	1783:1784	to	1783:1784	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	1	28	theme	human	151:155	arg1	milk					157:160	human milk	151:160	human milk	151:160	BACKGROUND Understanding how human milk impacts growth requires valid analytical methods for quantifying composition.					
37149285	2	29	from	source	311:316	arg1	milk					288:291	human milk	282:291	human milk	282:291	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	9	30	theme	Total	1653:1657	arg1	measurements					1672:1683	Total carbohydrate measurements	1653:1683	Total carbohydrate measurements assessed using infrared	1653:1707	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	8	31	theme	Native	1439:1444	arg1	samples					1461:1467	Native and HMO spiked samples	1439:1467	Native and HMO spiked samples	1439:1467	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	0	32	from	lactose	49:55	arg1	milk					90:93	human milk	84:93	human milk	84:93	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	9	33	theme	=	1761:1761	arg1	difference					1750:1759	mean difference	1745:1759	mean difference = 0.4 g/dL	1745:1770	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	6	34	theme	enzymatic	1007:1015	arg1	assay					1017:1021	Megazyme enzymatic assay	998:1021	Megazyme enzymatic assay	998:1021	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	35	dep	methods	966:972	arg1	AOAC					975:978	AOAC	975:978	AOAC	975:978	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	8	36	dep	CI	1626:1627	arg1	to					1633:1634	to	1633:1634	to	1633:1634	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	36	dep	CI	1626:1627	arg1	p					1641:1641	p = 0.005	1641:1649	p = 0.005	1641:1649	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	3	37	theme	carbohydrate	415:426	arg1	matrices					428:435	the carbohydrate matrices	411:435	the carbohydrate matrices of bovine and human milk	411:460	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	37	theme	carbohydrate	415:426	arg1	different					472:480	different	472:480	different	472:480	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	38	theme	milk	457:460	arg1	matrices					428:435	the carbohydrate matrices	411:435	the carbohydrate matrices of bovine and human milk	411:460	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	38	theme	milk	457:460	arg1	different					472:480	different	472:480	different	472:480	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	11	39	theme	human	1996:2000	arg1	milk					2002:2005	human milk	1996:2005	human milk	1996:2005	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	9	40	theme	HMO	1732:1734	arg1	spiking					1736:1742	HMO spiking	1732:1742	HMO spiking	1732:1742	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	0	41	theme	total	61:65	arg1	carbohydrates					67:79	total carbohydrates	61:79	total carbohydrates	61:79	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	6	42	theme	ultra-performance	1052:1068	arg1	chromatography					1077:1090	ultra-performance liquid chromatography	1052:1090	ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS)	1052:1123	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	42	theme	ultra-performance	1052:1068	arg1	methods					966:972	4 methods	964:972	4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay)	964:1022	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	8	43	theme	AOAC	1519:1522	arg1	2006.06					1524:1530	AOAC 2006.06	1519:1530	AOAC 2006.06	1519:1530	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	3	44	theme	milk	518:521	arg1	oligosaccharides					523:538	human milk oligosaccharides	512:538	human milk oligosaccharides (HMOs)	512:545	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	44	theme	milk	518:521	arg1	HMOs					541:544	HMOs	541:544	HMOs	541:544	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	44	theme	milk	518:521	arg1	each					548:551	each	548:551	each	548:551	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	10	45	theme	r	1891:1891	arg1	>					1893:1893	r > 0.90	1891:1898	r > 0.90	1891:1898	Only AOAC methods 984.22 and 2006.06 for measuring lactose were very highly correlated (r > 0.90, p < 0.001).					
37149285	8	46	theme	mean	1595:1598	arg1	CI					1626:1627	mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4	1595:1638	CI	1626:1627	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	46	theme	mean	1595:1598	arg1	BioVision					1584:1592	BioVision	1584:1592	BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005)	1584:1650	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	47	dep	spiked	1454:1459	arg1	HMO					1450:1452	HMO	1450:1452	HMO	1450:1452	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	6	48	theme	BioVision	1025:1033	arg1	methods					966:972	4 methods	964:972	4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay)	964:1022	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	48	theme	BioVision	1025:1033	arg1	assay					1045:1049	BioVision enzymatic assay	1025:1049	BioVision enzymatic assay	1025:1049	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	8	49	theme	=	1611:1611	arg1	CI					1626:1627	mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4	1595:1638	CI	1626:1627	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	49	theme	=	1611:1611	arg1	BioVision					1584:1592	BioVision	1584:1592	BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005)	1584:1650	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	11	50	theme	AOAC	1924:1927	arg1	methods					1929:1935	CONCLUSION AOAC methods 984.22 and 2006.06	1913:1954	CONCLUSION AOAC methods 984.22 and 2006.06	1913:1954	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	10	51	theme	p	1901:1901	arg1	<					1903:1903	p < 0.001	1901:1909	p < 0.001	1901:1909	Only AOAC methods 984.22 and 2006.06 for measuring lactose were very highly correlated (r > 0.90, p < 0.001).					
37149285	8	52	theme	g/dL	1617:1620	arg1	CI					1626:1627	mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4	1595:1638	CI	1626:1627	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	52	theme	g/dL	1617:1620	arg1	BioVision					1584:1592	BioVision	1584:1592	BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005)	1584:1650	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	53	dep	RESULTS	1431:1437	arg1	different					1492:1500	different	1492:1500	different	1492:1500	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	53	dep	RESULTS	1431:1437	arg1	different					1568:1576	different	1568:1576	different	1568:1576	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	7	54	theme	AOAC	1367:1370	arg1	2006.06					1372:1378	AOAC 2006.06	1367:1378	AOAC 2006.06 prepared using both volume and weighted dilutions	1367:1428	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	12	55	theme	values	2150:2155	arg1	overestimate					2127:2138	an overestimate	2124:2138	an overestimate of energy values	2124:2155	HMOs influence other enzymatic methods, as well as infrared analysis, which leads to an overestimate of energy values.					
37149285	3	56	theme	human	512:516	arg1	oligosaccharides					523:538	human milk oligosaccharides	512:538	human milk oligosaccharides (HMOs)	512:545	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	56	theme	human	512:516	arg1	HMOs					541:544	HMOs	541:544	HMOs	541:544	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	3	56	theme	human	512:516	arg1	each					548:551	each	548:551	each	548:551	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	5	57	theme	experiments	836:846	arg1	experiments					836:846	experiments	836:846	experiments	836:846	METHODS Two sets of experiments were performed.					
37149285	5	57	theme	experiments	836:846	arg1	sets					828:831	METHODS Two sets	816:831	METHODS Two sets of experiments	816:846	METHODS Two sets of experiments were performed.					
37149285	9	58	dep	higher	1719:1724	arg1	CI					1776:1777	CI	1776:1777	CI	1776:1777	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	2	59	theme	energy	321:326	arg1	source					311:316	a predominant source	297:316	a predominant source of energy	297:326	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	2	59	theme	energy	321:326	arg1	constituent					267:277	the most abundant constituent	249:277	the most abundant constituent in human milk	249:291	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	2	59	theme	energy	321:326	arg1	Lactose					240:246	Lactose	240:246	Lactose	240:246	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	1	60	theme	valid	186:190	arg1	methods					203:209	valid analytical methods	186:209	valid analytical methods	186:209	BACKGROUND Understanding how human milk impacts growth requires valid analytical methods for quantifying composition.					
37149285	11	61	dep	methods	1929:1935	arg1	984.22					1937:1942	984.22	1937:1942	984.22	1937:1942	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	11	61	dep	methods	1929:1935	arg1	2006.06					1948:1954	2006.06	1948:1954	2006.06	1948:1954	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	3	62	theme	terminal	560:567	arg1	unit					577:580	a terminal lactose unit	558:580	a terminal lactose unit that may influence analytical methods	558:618	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	5	63	theme	METHODS	816:822	arg1	experiments					836:846	experiments	836:846	experiments	836:846	METHODS Two sets of experiments were performed.					
37149285	5	63	theme	METHODS	816:822	arg1	sets					828:831	METHODS Two sets	816:831	METHODS Two sets of experiments	816:846	METHODS Two sets of experiments were performed.					
37149285	0	64	from	carbohydrates	67:79	arg1	milk					90:93	human milk	84:93	human milk	84:93	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	7	65	theme	liquid	1309:1314	arg1	chromatography					1316:1329	high-performance liquid chromatography	1292:1329	high-performance liquid chromatography	1292:1329	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	8	66	theme	=	1643:1643	arg1	p					1641:1641	p = 0.005	1641:1649	p = 0.005	1641:1649	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	6	67	theme	human	900:904	arg1	n=16					920:923	n=16	920:923	n=16	920:923	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	67	theme	human	900:904	arg1	samples					911:917	native and HMO-spiked human milk samples	878:917	native and HMO-spiked human milk samples (n=16 each)	878:929	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	68	dep	n=16	920:923	arg1	each					925:928	each	925:928	each	925:928	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	10	69	theme	AOAC	1808:1811	arg1	methods					1813:1819	Only AOAC methods 984.22 and 2006.06	1803:1838	methods	1813:1819	Only AOAC methods 984.22 and 2006.06 for measuring lactose were very highly correlated (r > 0.90, p < 0.001).					
37149285	9	70	dep	CI	1776:1777	arg1	difference					1750:1759	mean difference	1745:1759	mean difference = 0.4 g/dL	1745:1770	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	1	71	theme	BACKGROUND	122:131	arg1	Understanding					133:145	BACKGROUND Understanding	122:145	BACKGROUND Understanding how human milk impacts growth	122:175	BACKGROUND Understanding how human milk impacts growth requires valid analytical methods for quantifying composition.					
37149285	3	72	theme	bovine	440:445	arg1	milk					457:460	bovine and human milk	440:460	bovine and human milk	440:460	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	2	73	theme	abundant	258:265	arg1	constituent					267:277	the most abundant constituent	249:277	the most abundant constituent in human milk	249:291	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	2	73	theme	abundant	258:265	arg1	Lactose					240:246	Lactose	240:246	Lactose	240:246	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	7	74	dep	chromatography	1316:1329	arg1	detection					1352:1360	detection	1352:1360	detection	1352:1360	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	6	75	theme	infrared	1130:1137	arg1	methods					966:972	4 methods	964:972	4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay)	964:1022	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	75	theme	infrared	1130:1137	arg1	analysis					1139:1146	infrared analysis	1130:1146	infrared analysis	1130:1146	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	0	76	theme	human	84:88	arg1	milk					90:93	human milk	84:93	human milk	84:93	The influence of oligosaccharides when measuring lactose and total carbohydrates in human milk and comparison of methods.					
37149285	12	77	theme	other	2054:2058	arg1	methods					2070:2076	other enzymatic methods	2054:2076	other enzymatic methods	2054:2076	HMOs influence other enzymatic methods, as well as infrared analysis, which leads to an overestimate of energy values.					
37149285	6	78	with	analysis	1139:1146	arg1	mass-spectroscopy					1097:1113	mass-spectroscopy	1097:1113	mass-spectroscopy (UPLC-MS)	1097:1123	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	78	with	analysis	1139:1146	arg1	UPLC-MS					1116:1122	UPLC-MS	1116:1122	UPLC-MS	1116:1122	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	9	79	dep	=	1761:1761	arg1	g/dL					1767:1770	0.4 g/dL	1763:1770	0.4 g/dL	1763:1770	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	9	80	theme	carbohydrate	1659:1670	arg1	measurements					1672:1683	Total carbohydrate measurements	1653:1683	Total carbohydrate measurements assessed using infrared	1653:1707	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	8	81	theme	spiked	1454:1459	arg1	samples					1461:1467	Native and HMO spiked samples	1439:1467	Native and HMO spiked samples	1439:1467	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	1	82	dep	Understanding	133:145	arg1	impacts					162:168	impacts	162:168	impacts growth	162:175	BACKGROUND Understanding how human milk impacts growth requires valid analytical methods for quantifying composition.					
37149285	6	83	dep	AOAC	975:978	arg1	based					989:993	based	989:993	based on Megazyme enzymatic assay	989:1021	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	4	84	from	carbohydrates	734:746	arg1	milk					757:760	human milk	751:760	human milk	751:760	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	4	85	theme	human	751:755	arg1	milk					757:760	human milk	751:760	human milk	751:760	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	2	86	theme	dairy	386:390	arg1	industry					392:399	the bovine dairy industry	375:399	the bovine dairy industry	375:399	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	7	87	from	984.22	1274:1279	arg1	milk					1263:1266	bovine milk	1256:1266	bovine milk	1256:1266	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	6	88	theme	Megazyme	998:1005	arg1	assay					1017:1021	Megazyme enzymatic assay	998:1021	Megazyme enzymatic assay	998:1021	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	4	89	theme	analytical	701:710	arg1	methods					712:718	common analytical methods	694:718	common analytical methods for measuring carbohydrates in human milk	694:760	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	7	90	theme	approved	1222:1229	arg1	methods					1214:1220	two methods	1210:1220	two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions	1210:1428	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	7	91	dep	dilutions	1420:1428	arg1	both					1395:1398	both	1395:1398	both	1395:1398	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	7	91	dep	dilutions	1420:1428	arg1	weighted					1411:1418	weighted	1411:1418	weighted	1411:1418	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	4	92	dep	OBJECTIVE	621:629	arg1	were					641:644	were	641:644	were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose	641:813	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	2	93	from	constituent	267:277	arg1	milk					288:291	human milk	282:291	human milk	282:291	Lactose, the most abundant constituent in human milk and a predominant source of energy, is often assessed using methods borrowed from the bovine dairy industry.					
37149285	3	94	theme	analytical	601:610	arg1	methods					612:618	analytical methods	601:618	analytical methods	601:618	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	4	95	theme	common	778:783	arg1	methods					785:791	common methods	778:791	common methods	778:791	OBJECTIVE Our goals were to determine the extent to which HMOs influence common analytical methods for measuring carbohydrates in human milk, and to compare common methods for measuring lactose.					
37149285	3	96	theme	human	451:455	arg1	milk					457:460	bovine and human milk	440:460	bovine and human milk	440:460	However, the carbohydrate matrices of bovine and human milk are quite different, especially as they relate to human milk oligosaccharides (HMOs), each with a terminal lactose unit that may influence analytical methods.					
37149285	6	97	theme	liquid	1070:1075	arg1	chromatography					1077:1090	ultra-performance liquid chromatography	1052:1090	ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS)	1052:1123	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	97	theme	liquid	1070:1075	arg1	methods					966:972	4 methods	964:972	4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay)	964:1022	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	10	98	dep	correlated	1879:1888	arg1	>					1893:1893	r > 0.90	1891:1898	r > 0.90	1891:1898	Only AOAC methods 984.22 and 2006.06 for measuring lactose were very highly correlated (r > 0.90, p < 0.001).					
37149285	7	99	dep	both	1395:1398	arg1	volume					1400:1405	volume	1400:1405	volume	1400:1405	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	9	100	theme	mean	1745:1748	arg1	difference					1750:1759	mean difference	1745:1759	mean difference = 0.4 g/dL	1745:1770	Total carbohydrate measurements assessed using infrared were also higher after HMO spiking (mean difference = 0.4 g/dL, 95%CI 0.3 to 0.6, p < 0.001).					
37149285	8	101	theme	difference	1600:1609	arg1	CI					1626:1627	mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4	1595:1638	CI	1626:1627	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	8	101	theme	difference	1600:1609	arg1	BioVision					1584:1592	BioVision	1584:1592	BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005)	1584:1650	RESULTS Native and HMO spiked samples were not significantly different in lactose using AOAC 2006.06 and UPLC-MS, but were significantly different using BioVision (mean difference = 0.2 g/dL, 95%CI 0.1 to 0.4, p = 0.005).					
37149285	7	102	from	lactose	1245:1251	arg1	milk					1263:1266	bovine milk	1256:1266	bovine milk	1256:1266	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	6	103	theme	enzymatic	1035:1043	arg1	methods					966:972	4 methods	964:972	4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay)	964:1022	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	103	theme	enzymatic	1035:1043	arg1	assay					1045:1049	BioVision enzymatic assay	1025:1049	BioVision enzymatic assay	1025:1049	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	7	104	theme	bovine	1256:1261	arg1	milk					1263:1266	bovine milk	1256:1266	bovine milk	1256:1266	In the second, human milk samples (n=20) were assessed using two methods approved for measuring lactose in bovine milk: AOAC 984.22 which uses high-performance liquid chromatography and refractive index detection; and AOAC 2006.06 prepared using both volume and weighted dilutions.					
37149285	11	105	from	lactose	1985:1991	arg1	milk					2002:2005	human milk	1996:2005	human milk	1996:2005	CONCLUSION AOAC methods 984.22 and 2006.06 are comparable for measuring lactose in human milk and are not influenced by HMOs.					
37149285	6	106	with	chromatography	1077:1090	arg1	mass-spectroscopy					1097:1113	mass-spectroscopy	1097:1113	mass-spectroscopy (UPLC-MS)	1097:1123	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
37149285	6	106	with	chromatography	1077:1090	arg1	UPLC-MS					1116:1122	UPLC-MS	1116:1122	UPLC-MS	1116:1122	In the first, native and HMO-spiked human milk samples (n=16 each) were assessed and compared using 4 methods: AOAC 2006.06 (based on Megazyme enzymatic assay), BioVision enzymatic assay, ultra-performance liquid chromatography with mass-spectroscopy (UPLC-MS), and infrared analysis.					
35704413	0	0	theme	phosphate	77:85	arg1	removal					66:72	efficient removal	56:72	efficient removal of phosphate from aqueous solutions: batch and column studies	56:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	3	1	from	application	612:622	arg1	columns					627:633	columns	627:633	columns	627:633	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	8	2	contain	has	1208:1210	arg1	composite					1198:1206	Al2O3/CA composite	1189:1206	Al2O3/CA composite	1189:1206	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	8	2	contain	has	1208:1210	arg1	approach					1303:1310	a promising approach	1291:1310	a promising approach for phosphate removal from water	1291:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	8	2	contain	has	1208:1210	arg2	capacity					1230:1237	better adsorption capacity	1212:1237	better adsorption capacity	1212:1237	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	4	3	theme	BET	640:642	arg1	area					652:655	The BET surface area	636:655	The BET surface area of Al2O3/CA	636:667	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	4	4	theme	37.31	707:711	arg1	m2/g					713:716	37.31 m2/g	707:716	37.31 m2/g of Al2O3	707:725	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	6	5	theme	aluminum	930:937	arg1	precipitation					949:961	aluminum phosphate precipitation	930:961	aluminum phosphate precipitation	930:961	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	7	6	theme	phosphate	1135:1143	arg1	concentration					1145:1157	phosphate concentration	1135:1157	phosphate concentration	1135:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	5	7	theme	pure	834:837	arg1	Al2O3					839:843	pure Al2O3	834:843	pure Al2O3 by Langmuir fitting	834:863	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	0	8	theme	aqueous	92:98	arg1	solutions					100:108	aqueous solutions	92:108	aqueous solutions: batch and column studies	92:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	3	9	theme	Al2O3/CA	527:534	arg1	composite					536:544	Al2O3/CA composite	527:544	Al2O3/CA composite	527:544	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	8	10	theme	adsorption	1270:1279	arg1	system					1281:1286	the dynamic adsorption system	1258:1286	the dynamic adsorption system	1258:1286	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	7	11	theme	rates	1125:1129	arg1	amount					1065:1070	the amount	1061:1070	the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration	1061:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	11	theme	rates	1125:1129	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	11	theme	rates	1125:1129	arg1	concentration					1145:1157	phosphate concentration	1135:1157	phosphate concentration	1135:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	11	theme	rates	1125:1129	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	11	theme	rates	1125:1129	arg1	height					1103:1108	bed height	1099:1108	bed height	1099:1108	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	5	12	from	capacity	751:758	arg1	Al2O3/CA					776:783	Al2O3/CA	776:783	Al2O3/CA	776:783	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	8	13	theme	dynamic	1262:1268	arg1	system					1281:1286	the dynamic adsorption system	1258:1286	the dynamic adsorption system	1258:1286	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	0	14	dep	solutions	100:108	arg1	batch					111:115	batch	111:115	batch	111:115	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	0	14	dep	solutions	100:108	arg1	studies					128:134	column studies	121:134	column studies	121:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	8	15	from	water	1339:1343	arg1	removal					1326:1332	phosphate removal	1316:1332	phosphate removal from water	1316:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	7	16	from	adsorption	1009:1018	arg1	Al2O3/CA					1036:1043	Al2O3/CA	1036:1043	Al2O3/CA	1036:1043	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	8	17	theme	adsorption	1219:1228	arg1	capacity					1230:1237	better adsorption capacity	1212:1237	better adsorption capacity	1212:1237	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	5	18	theme	Langmuir	848:855	arg1	fitting					857:863	Langmuir fitting	848:863	Langmuir fitting	848:863	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	2	19	theme	flow	365:368	arg1	treatment					370:378	continuous flow treatment	354:378	continuous flow treatment	354:378	While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications.					
35704413	7	20	theme	influent	1111:1118	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	21	theme	outer	1075:1079	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	22	theme	flow	1120:1123	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	3	23	contain	has	553:555	arg2	size					583:586	relatively large particle size	557:586	relatively large particle size	557:586	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	3	23	contain	has	553:555	arg1	composite					536:544	Al2O3/CA composite	527:544	Al2O3/CA composite	527:544	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	2	24	theme	continuous	354:363	arg1	treatment					370:378	continuous flow treatment	354:378	continuous flow treatment	354:378	While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications.					
35704413	5	25	theme	maximum	732:738	arg1	capacity					751:758	The maximum adsorption capacity	728:758	The maximum adsorption capacity of phosphate on Al2O3/CA	728:783	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	8	26	theme	promising	1293:1301	arg1	composite					1198:1206	Al2O3/CA composite	1189:1206	Al2O3/CA composite	1189:1206	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	8	26	theme	promising	1293:1301	arg1	approach					1303:1310	a promising approach	1291:1310	a promising approach for phosphate removal from water	1291:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	7	27	theme	bed	1099:1101	arg1	height					1103:1108	bed height	1099:1108	bed height	1099:1108	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	5	28	theme	adsorption	740:749	arg1	capacity					751:758	The maximum adsorption capacity	728:758	The maximum adsorption capacity of phosphate on Al2O3/CA	728:783	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	7	29	theme	phosphate	1023:1031	arg1	adsorption					1009:1018	the adsorption	1005:1018	the adsorption of phosphate on Al2O3/CA	1005:1043	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	0	30	theme	calcium	22:28	arg1	alginate					30:37	calcium alginate	22:37	calcium alginate	22:37	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	1	31	theme	eutrophication	258:271	arg1	phenomenon					273:282	the eutrophication phenomenon	254:282	the eutrophication phenomenon	254:282	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	5	32	theme	phosphate	763:771	arg1	capacity					751:758	The maximum adsorption capacity	728:758	The maximum adsorption capacity of phosphate on Al2O3/CA	728:783	The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting.					
35704413	6	33	theme	phosphate	888:896	arg1	adsorption					898:907	phosphate adsorption	888:907	phosphate adsorption	888:907	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	4	34	theme	51.73	682:686	arg1	m2/g					688:691	51.73 m2/g	682:691	51.73 m2/g	682:691	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	8	35	theme	Al2O3/CA	1189:1196	arg1	composite					1198:1206	Al2O3/CA composite	1189:1206	Al2O3/CA composite	1189:1206	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	8	35	theme	Al2O3/CA	1189:1196	arg1	approach					1303:1310	a promising approach	1291:1310	a promising approach for phosphate removal from water	1291:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	4	36	theme	Al2O3	721:725	arg1	m2/g					713:716	37.31 m2/g	707:716	37.31 m2/g of Al2O3	707:725	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	4	37	theme	surface	644:650	arg1	area					652:655	The BET surface area	636:655	The BET surface area of Al2O3/CA	636:667	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	7	38	theme	height	1103:1108	arg1	amount					1065:1070	the amount	1061:1070	the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration	1061:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	38	theme	height	1103:1108	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	38	theme	height	1103:1108	arg1	concentration					1145:1157	phosphate concentration	1135:1157	phosphate concentration	1135:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	38	theme	height	1103:1108	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	38	theme	height	1103:1108	arg1	height					1103:1108	bed height	1099:1108	bed height	1099:1108	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	8	39	theme	better	1212:1217	arg1	capacity					1230:1237	better adsorption capacity	1212:1237	better adsorption capacity	1212:1237	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	7	40	theme	calcium	1081:1087	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	0	41	theme	column	121:126	arg1	studies					128:134	column studies	121:134	column studies	121:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	2	42	theme	practical	398:406	arg1	applications					408:419	its practical applications	394:419	its practical applications	394:419	While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications.					
35704413	6	43	theme	main	870:873	arg1	mechanism					875:883	The main mechanism	866:883	The main mechanism of phosphate adsorption	866:907	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	6	43	theme	main	870:873	arg1	formation					917:925	the formation	913:925	the formation of aluminum phosphate precipitation	913:961	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	7	44	theme	column	978:983	arg1	studies					985:991	the column studies	974:991	the column studies	974:991	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	6	45	theme	adsorption	898:907	arg1	mechanism					875:883	The main mechanism	866:883	The main mechanism of phosphate adsorption	866:907	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	6	45	theme	adsorption	898:907	arg1	formation					917:925	the formation	913:925	the formation of aluminum phosphate precipitation	913:961	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	1	46	used	used	179:182	arg2	Al2O3					156:160	Al2O3	156:160	Al2O3	156:160	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	1	46	used	used	179:182	arg2	alumina					147:153	Activated alumina	137:153	Activated alumina (Al2O3)	137:161	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	2	47	theme	powder	308:313	arg1	material					315:322	a fine powder material	301:322	a fine powder material	301:322	While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications.					
35704413	4	48	theme	Al2O3/CA	660:667	arg1	area					652:655	The BET surface area	636:655	The BET surface area of Al2O3/CA	636:667	The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3.					
35704413	7	49	theme	alginate	1089:1096	arg1	amount					1065:1070	the amount	1061:1070	the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration	1061:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	49	theme	alginate	1089:1096	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	49	theme	alginate	1089:1096	arg1	concentration					1145:1157	phosphate concentration	1135:1157	phosphate concentration	1135:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	49	theme	alginate	1089:1096	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	49	theme	alginate	1089:1096	arg1	height					1103:1108	bed height	1099:1108	bed height	1099:1108	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	0	50	from	solutions	100:108	arg1	removal					66:72	efficient removal	56:72	efficient removal of phosphate from aqueous solutions: batch and column studies	56:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	3	51	theme	large	568:572	arg1	size					583:586	relatively large particle size	557:586	relatively large particle size	557:586	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	8	52	theme	phosphate	1316:1324	arg1	removal					1326:1332	phosphate removal	1316:1332	phosphate removal from water	1316:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	2	53	theme	fine	303:306	arg1	material					315:322	a fine powder material	301:322	a fine powder material	301:322	While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications.					
35704413	1	54	theme	aqueous	194:200	arg1	pollutants					210:219	aqueous anionic pollutants	194:219	aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon	194:282	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	1	54	theme	aqueous	194:200	arg1	phosphate					229:237	phosphate	229:237	phosphate	229:237	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	3	55	theme	calcium	492:498	arg1	alginate					500:507	calcium alginate	492:507	calcium alginate (CA)	492:512	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	3	55	theme	calcium	492:498	arg1	CA					510:511	CA	510:511	CA	510:511	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	3	56	theme	particle	574:581	arg1	size					583:586	relatively large particle size	557:586	relatively large particle size	557:586	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	3	57	theme	new	444:446	arg1	strategy					448:455	a new strategy	442:455	a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns	442:633	Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns.					
35704413	1	58	theme	anionic	202:208	arg1	pollutants					210:219	aqueous anionic pollutants	194:219	aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon	194:282	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	1	58	theme	anionic	202:208	arg1	phosphate					229:237	phosphate	229:237	phosphate	229:237	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	7	59	theme	concentration	1145:1157	arg1	amount					1065:1070	the amount	1061:1070	the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration	1061:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	59	theme	concentration	1145:1157	arg1	rates					1125:1129	influent flow rates	1111:1129	influent flow rates	1111:1129	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	59	theme	concentration	1145:1157	arg1	concentration					1145:1157	phosphate concentration	1135:1157	phosphate concentration	1135:1157	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	59	theme	concentration	1145:1157	arg1	alginate					1089:1096	outer calcium alginate	1075:1096	outer calcium alginate	1075:1096	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	7	59	theme	concentration	1145:1157	arg1	height					1103:1108	bed height	1099:1108	bed height	1099:1108	Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration.					
35704413	6	60	theme	precipitation	949:961	arg1	mechanism					875:883	The main mechanism	866:883	The main mechanism of phosphate adsorption	866:907	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	6	60	theme	precipitation	949:961	arg1	formation					917:925	the formation	913:925	the formation of aluminum phosphate precipitation	913:961	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35704413	0	61	theme	efficient	56:64	arg1	removal					66:72	efficient removal	56:72	efficient removal of phosphate from aqueous solutions: batch and column studies	56:134	Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies.					
35704413	8	62	used	used	1250:1253	arg2	composite					1198:1206	Al2O3/CA composite	1189:1206	Al2O3/CA composite	1189:1206	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	8	62	used	used	1250:1253	arg2	approach					1303:1310	a promising approach	1291:1310	a promising approach for phosphate removal from water	1291:1343	This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.					
35704413	1	63	theme	Activated	137:145	arg1	Al2O3					156:160	Al2O3	156:160	Al2O3	156:160	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	1	63	theme	Activated	137:145	arg1	alumina					147:153	Activated alumina	137:153	Activated alumina (Al2O3)	137:161	Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon.					
35704413	6	64	theme	phosphate	939:947	arg1	precipitation					949:961	aluminum phosphate precipitation	930:961	aluminum phosphate precipitation	930:961	The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation.					
35013951	6	0	theme	plant	751:755	arg1	length					757:762	a plant length	749:762	a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	749:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	5	1	theme	embedded	432:439	arg1	beads					461:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	0	2	theme	composite	95:103	arg1	material					105:112	a hydrotalcite/alginate composite material	71:112	a hydrotalcite/alginate composite material	71:112	Novel bio-fertilizer based on nitrogen-fixing bacterium immobilized in a hydrotalcite/alginate composite material.					
35013951	7	3	dep	container	1025:1033	arg1	keep					1038:1041	keep	1038:1041	to keep the bacteria	1035:1054	In short, the present results demonstrate that the hydrotalcite and alginate served as an excellent container to keep the bacteria alive, providing nutrients to them and controlling their delivery.					
35013951	7	4	theme	excellent	1015:1023	arg1	container					1025:1033	an excellent container	1012:1033	an excellent container to keep the bacteria	1012:1054	In short, the present results demonstrate that the hydrotalcite and alginate served as an excellent container to keep the bacteria alive, providing nutrients to them and controlling their delivery.					
35013951	7	5	theme	present	939:945	arg1	results					947:953	the present results	935:953	the present results	935:953	In short, the present results demonstrate that the hydrotalcite and alginate served as an excellent container to keep the bacteria alive, providing nutrients to them and controlling their delivery.					
35013951	5	6	from	calcium	444:450	arg1	embedded					432:439	embedded	432:439	embedded	432:439	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	7	used	used	597:600	arg2	reservoir					531:539	a bacterial reservoir	519:539	a bacterial reservoir	519:539	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	7	used	used	597:600	arg2	bio-fertilizer					607:620	a bio-fertilizer	605:620	a bio-fertilizer	605:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	7	used	used	597:600	arg2	material					569:576	a controlled release material	548:576	a controlled release material for bacteria	548:589	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	7	used	used	597:600	arg2	bio-composite					487:499	a novel bio-composite	479:499	a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer	479:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	3	8	theme	bio-stimulant	267:279	arg1	capacity					281:288	bio-stimulant capacity	267:288	bio-stimulant capacity	267:288	This bacterium can produce substances with bio-stimulant capacity through the fixation of nitrogen from the air.					
35013951	5	9	from	embedded	432:439	arg1	calcium					444:450	calcium	444:450	calcium	444:450	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	2	10	theme	common	151:156	arg1	genus					158:162	a common genus	149:162	a common genus of the actinomycetes class found in soils and rhizospheres	149:221	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	5	11	theme	bacterial	521:529	arg1	bio-composite					487:499	a novel bio-composite	479:499	a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer	479:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	11	theme	bacterial	521:529	arg1	reservoir					531:539	a bacterial reservoir	519:539	a bacterial reservoir	519:539	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	0	12	theme	Novel	0:4	arg1	bio-fertilizer					6:19	Novel bio-fertilizer	0:19	Novel bio-fertilizer	0:19	Novel bio-fertilizer based on nitrogen-fixing bacterium immobilized in a hydrotalcite/alginate composite material.					
35013951	6	13	dep	760	841:843	arg1	ca.					837:839	ca.	837:839	ca.	837:839	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	4	14	dep	sp	368:369	arg1	work					345:348	this work	340:348	this work	340:348	In this work, the Streptomyces sp.					
35013951	6	15	from	increase	825:832	arg1	comparison					877:886	comparison	877:886	comparison with the materials without bacteria	877:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	15	from	increase	825:832	arg1	growth					867:872	the lettuce plant growth	849:872	the lettuce plant growth	849:872	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	16	theme	growing	792:798	arg1	14 days					781:787	only 14 days	776:787	only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	776:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	1	17	theme	bacterium	119:127	arg1	sp					142:143	The bacterium Streptomyces sp	115:143	The bacterium Streptomyces sp.	115:144	The bacterium Streptomyces sp.					
35013951	5	18	theme	novel	481:485	arg1	bio-composite					487:499	a novel bio-composite	479:499	a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer	479:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	18	theme	novel	481:485	arg1	material					569:576	a controlled release material	548:576	a controlled release material for bacteria	548:589	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	18	theme	novel	481:485	arg1	reservoir					531:539	a bacterial reservoir	519:539	a bacterial reservoir	519:539	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	18	theme	novel	481:485	arg1	bio-fertilizer					607:620	a bio-fertilizer	605:620	a bio-fertilizer	605:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	2	19	located	found	191:195	arg1	rhizospheres					210:221	rhizospheres	210:221	rhizospheres	210:221	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	2	19	located	found	191:195	arg2	class					185:189	the actinomycetes class	167:189	the actinomycetes class found in soils and rhizospheres	167:221	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	2	19	located	found	191:195	arg1	soils					200:204	soils	200:204	soils	200:204	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	1	20	theme	Streptomyces	129:140	arg1	sp					142:143	The bacterium Streptomyces sp	115:143	The bacterium Streptomyces sp.	115:144	The bacterium Streptomyces sp.					
35013951	6	21	with	comparison	877:886	arg1	materials					897:905	the materials	893:905	the materials without bacteria	893:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	22	theme	plant	861:865	arg1	growth					867:872	the lettuce plant growth	849:872	the lettuce plant growth	849:872	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	0	23	theme	nitrogen-fixing	30:44	arg1	bacterium					46:54	nitrogen-fixing bacterium	30:54	nitrogen-fixing bacterium immobilized in a hydrotalcite/alginate composite material	30:112	Novel bio-fertilizer based on nitrogen-fixing bacterium immobilized in a hydrotalcite/alginate composite material.					
35013951	2	24	theme	class	185:189	arg1	genus					158:162	a common genus	149:162	a common genus of the actinomycetes class found in soils and rhizospheres	149:221	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	5	25	theme	controlled	550:559	arg1	bio-composite					487:499	a novel bio-composite	479:499	a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer	479:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	25	theme	controlled	550:559	arg1	material					569:576	a controlled release material	548:576	a controlled release material for bacteria	548:589	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	2	26	theme	actinomycetes	171:183	arg1	class					185:189	the actinomycetes class	167:189	the actinomycetes class found in soils and rhizospheres	167:221	is a common genus of the actinomycetes class found in soils and rhizospheres.					
35013951	5	27	theme	release	561:567	arg1	bio-composite					487:499	a novel bio-composite	479:499	a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer	479:620	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	5	27	theme	release	561:567	arg1	material					569:576	a controlled release material	548:576	a controlled release material for bacteria	548:589	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	3	28	with	substances	251:260	arg1	capacity					281:288	bio-stimulant capacity	267:288	bio-stimulant capacity	267:288	This bacterium can produce substances with bio-stimulant capacity through the fixation of nitrogen from the air.					
35013951	6	29	theme	only	776:779	arg1	14 days					781:787	only 14 days	776:787	only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	776:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	30	theme	lettuce	853:859	arg1	growth					867:872	the lettuce plant growth	849:872	the lettuce plant growth	849:872	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	5	31	theme	alginate	452:459	arg1	beads					461:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	3	32	theme	nitrogen	314:321	arg1	fixation					302:309	the fixation	298:309	the fixation of nitrogen from the air	298:334	This bacterium can produce substances with bio-stimulant capacity through the fixation of nitrogen from the air.					
35013951	6	33	theme	%	844:844	arg1	increase					825:832	an increase	822:832	an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	822:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	4	34	theme	Streptomyces	355:366	arg1	sp					368:369	the Streptomyces sp	351:369	the Streptomyces sp	351:369	In this work, the Streptomyces sp.					
35013951	6	35	theme	bacterium-hydrotalcite/alginate	656:686	arg1	efficient					711:719	efficient	711:719	efficient	711:719	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	35	theme	bacterium-hydrotalcite/alginate	656:686	arg1	bio-composite					688:700	the novel bacterium-hydrotalcite/alginate bio-composite	646:700	the novel bacterium-hydrotalcite/alginate bio-composite	646:700	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	36	theme	64 mm	767:771	arg1	length					757:762	a plant length	749:762	a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	749:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	7	37	dep	hydrotalcite	976:987	arg1	the					972:974	the	972:974	the	972:974	In short, the present results demonstrate that the hydrotalcite and alginate served as an excellent container to keep the bacteria alive, providing nutrients to them and controlling their delivery.					
35013951	6	38	theme	novel	650:654	arg1	efficient					711:719	efficient	711:719	efficient	711:719	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	6	38	theme	novel	650:654	arg1	bio-composite					688:700	the novel bacterium-hydrotalcite/alginate bio-composite	646:700	the novel bacterium-hydrotalcite/alginate bio-composite	646:700	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	0	39	theme	hydrotalcite/alginate	73:93	arg1	material					105:112	a hydrotalcite/alginate composite material	71:112	a hydrotalcite/alginate composite material	71:112	Novel bio-fertilizer based on nitrogen-fixing bacterium immobilized in a hydrotalcite/alginate composite material.					
35013951	6	40	from	length	757:762	arg1	14 days					781:787	only 14 days	776:787	only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria	776:922	The results showed that the novel bacterium-hydrotalcite/alginate bio-composite was very efficient as a bio-fertilizer showing a plant length of 64 mm in only 14 days of growing, which corresponds to an increase of ca. 760% in the lettuce plant growth in comparison with the materials without bacteria.					
35013951	5	41	theme	ZnMgAl-hydrotalcite	403:421	arg1	clay					423:426	a ZnMgAl-hydrotalcite clay	401:426	a ZnMgAl-hydrotalcite clay	401:426	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
35013951	3	42	from	air	332:334	arg1	fixation					302:309	the fixation	298:309	the fixation of nitrogen from the air	298:334	This bacterium can produce substances with bio-stimulant capacity through the fixation of nitrogen from the air.					
35013951	5	43	theme	clay	423:426	arg1	beads					461:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads	401:465	bacterium was immobilized on a ZnMgAl-hydrotalcite clay and embedded in calcium alginate beads to generate a novel bio-composite that functions as a bacterial reservoir and as a controlled release material for bacteria to be used as a bio-fertilizer.					
36041062	4	0	theme	D-mannitol	844:853	arg1	concentration					855:867	D-mannitol concentration	844:867	D-mannitol concentration in the blood	844:880	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	7	1	theme	mouse	1475:1479	arg1	model					1481:1485	the low-grade inflammation mouse model	1448:1485	the low-grade inflammation mouse model	1448:1485	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	0	2	with	Model	62:66	arg1	Inflammation					103:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	7	3	theme	low-grade	1452:1460	arg1	inflammation					1462:1473	low-grade inflammation	1452:1473	the low-grade inflammation mouse model	1448:1485	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	7	4	theme	lipid	1413:1417	arg1	profile					1419:1425	the blood lipid profile	1403:1425	the blood lipid profile	1403:1425	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	10	5	theme	metabolic	1957:1965	arg1	balance					1967:1973	an unhealthy diet-impaired metabolic balance	1930:1973	an unhealthy diet-impaired metabolic balance	1930:1973	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36041062	6	6	theme	d-galactarate	1244:1256	arg1	pathways					1270:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	3	7	theme	IMD	504:506	arg1	pre-treatment					487:499	pre-treatment	487:499	pre-treatment of IMD at 5% (w/v)	487:518	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	8	8	theme	IRS-1	1735:1739	arg1	expression					1741:1750	the adiponectin, PPAR-γ, and IRS-1 expression	1706:1750	expression	1741:1750	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	7	9	from	level	1439:1443	arg1	model					1481:1485	the low-grade inflammation mouse model	1448:1485	the low-grade inflammation mouse model	1448:1485	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	6	10	theme	microbial	1134:1142	arg1	diversity					1144:1152	the microbial diversity	1130:1152	the microbial diversity	1130:1152	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	6	11	theme	d-glucarate	1228:1238	arg1	pathways					1270:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	10	12	theme	immune	1991:1996	arg1	homeostasis					1998:2008	immune homeostasis	1991:2008	immune homeostasis	1991:2008	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36041062	6	13	theme	related	1220:1226	arg1	pathways					1270:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	8	14	from	responses	1606:1614	arg1	tissues					1642:1648	inflamed white adipose tissues	1619:1648	inflamed white adipose tissues	1619:1648	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	1	15	theme	gut	201:203	arg1	integrity					205:213	gut integrity	201:213	gut integrity	201:213	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	1	16	from	composition	230:240	arg1	HFD					262:264	HFD	262:264	HFD	262:264	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	1	16	from	composition	230:240	arg1	diet					256:259	a high-fat diet	245:259	a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	245:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	1	17	dep	diet	256:259	arg1	model					336:340	mouse model	330:340	a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	245:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	10	18	theme	disorders	2055:2063	arg1	development					2030:2040	the development	2026:2040	the development of metabolic disorders	2026:2063	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36041062	5	19	theme	associated	1027:1036	arg1	dysbiosis					1038:1046	associated dysbiosis	1027:1046	associated dysbiosis	1027:1046	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	3	20	theme	mediators	583:591	arg1	concentration					535:547	the concentration	531:547	the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6	531:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	0	21	theme	Mouse	56:60	arg1	Model					62:66	a High-Fat Diet Mouse Model	40:66	a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation	40:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	1	22	theme	low-grade	307:315	arg1	inflammation					317:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	4	23	theme	structural	719:728	arg1	integrity					730:738	the structural integrity	715:738	the structural integrity	715:738	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	0	24	theme	Low-Grade	85:93	arg1	Inflammation					103:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	1	25	theme	mouse	330:334	arg1	model					336:340	mouse model	330:340	a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	245:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	2	26	theme	immune	366:371	arg1	response					373:380	the immune response	362:380	the immune response	362:380	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	9	27	theme	potential	1808:1816	arg1	prebiotic					1818:1826	a potential prebiotic	1806:1826	a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function	1806:1905	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	8	28	theme	IMD	1520:1522	arg1	supplementation					1524:1538	IMD supplementation	1520:1538	IMD supplementation	1520:1538	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	4	29	theme	IMD	684:686	arg1	supplementation					688:702	IMD supplementation	684:702	IMD supplementation	684:702	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	0	30	theme	Regulatory	0:9	arg1	Effect					11:16	Regulatory Effect	0:16	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.	0:115	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	4	31	theme	tight	788:792	arg1	expressions					811:821	the tight junction protein expressions	784:821	the tight junction protein expressions	784:821	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	2	32	theme	metabolic	428:436	arg1	syndromes					438:446	developing metabolic syndromes	417:446	developing metabolic syndromes	417:446	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	4	33	theme	protein	803:809	arg1	expressions					811:821	the tight junction protein expressions	784:821	the tight junction protein expressions	784:821	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	0	34	theme	High-Fat	42:49	arg1	Model					62:66	a High-Fat Diet Mouse Model	40:66	a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation	40:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	5	35	theme	metabolic	1001:1009	arg1	endotoxemia					1011:1021	metabolic endotoxemia	1001:1021	metabolic endotoxemia	1001:1021	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	9	36	theme	gut	1859:1861	arg1	composition					1874:1884	a healthy gut microbiota composition	1849:1884	a healthy gut microbiota composition	1849:1884	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	6	37	theme	IMD	1089:1091	arg1	supplementation					1093:1107	IMD supplementation	1089:1107	IMD supplementation	1089:1107	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	1	38	theme	microbiota	219:228	arg1	composition					230:240	microbiota composition	219:240	microbiota composition	219:240	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	5	39	theme	unhealthy	968:976	arg1	factors					986:992	unhealthy dietary factors	968:992	unhealthy dietary factors	968:992	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	9	40	theme	barrier	1890:1896	arg1	function					1898:1905	barrier function	1890:1905	barrier function	1890:1905	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	8	41	theme	inflamed	1619:1626	arg1	tissues					1642:1648	inflamed white adipose tissues	1619:1648	inflamed white adipose tissues	1619:1648	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	3	42	theme	study	469:473	arg1	results					453:459	The results	449:459	The results of this study	449:473	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	4	43	from	concentration	855:867	arg1	blood					876:880	the blood	872:880	the blood	872:880	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	7	44	theme	inflammation	1462:1473	arg1	model					1481:1485	the low-grade inflammation mouse model	1448:1485	the low-grade inflammation mouse model	1448:1485	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	8	45	theme	adipose	1634:1640	arg1	tissues					1642:1648	inflamed white adipose tissues	1619:1648	inflamed white adipose tissues	1619:1648	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	3	46	theme	adiponectin	637:647	arg1	level					649:653	the adiponectin level	633:653	the adiponectin level in the plasma	633:667	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	8	47	theme	adiponectin	1710:1720	arg1	PPAR-γ					1723:1728	the adiponectin, PPAR-γ, and IRS-1 expression	1706:1750	PPAR-γ	1723:1728	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	1	48	theme	high-fat	247:254	arg1	HFD					262:264	HFD	262:264	HFD	262:264	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	1	48	theme	high-fat	247:254	arg1	diet					256:259	a high-fat diet	245:259	a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	245:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	7	49	theme	glucose	1431:1437	arg1	level					1439:1443	glucose level	1431:1443	glucose level	1431:1443	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	6	50	theme	degradation	1258:1268	arg1	pathways					1270:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	the related d-glucarate and d-galactarate degradation pathways	1216:1277	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	3	51	from	pre-treatment	487:499	arg1	w/v					515:517	w/v	515:517	w/v	515:517	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	51	from	pre-treatment	487:499	arg1	%					512:512	5%	511:512	5% (w/v)	511:518	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	1	52	theme	isomaltodextrin	161:175	arg1	effects					150:156	the effects	146:156	the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	146:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	9	53	theme	healthy	1851:1857	arg1	composition					1874:1884	a healthy gut microbiota composition	1849:1884	a healthy gut microbiota composition	1849:1884	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	10	54	theme	diet-impaired	1943:1955	arg1	balance					1967:1973	an unhealthy diet-impaired metabolic balance	1930:1973	an unhealthy diet-impaired metabolic balance	1930:1973	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36041062	7	55	theme	blood	1407:1411	arg1	profile					1419:1425	the blood lipid profile	1403:1425	the blood lipid profile	1403:1425	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	6	56	theme	able	1338:1341	arg1	prebiotic					1328:1336	a prebiotic	1326:1336	a prebiotic able to promote energy homeostasis	1326:1371	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	6	56	theme	able	1338:1341	arg1	benefits					1307:1314	the benefits	1303:1314	the benefits of IMD	1303:1321	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	1	57	dep	integrity	205:213	arg1	the					197:199	the	197:199	the	197:199	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	3	58	from	level	649:653	arg1	plasma					662:667	the plasma	658:667	the plasma	658:667	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	6	59	theme	IMD	1319:1321	arg1	prebiotic					1328:1336	a prebiotic	1326:1336	a prebiotic able to promote energy homeostasis	1326:1371	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	6	59	theme	IMD	1319:1321	arg1	benefits					1307:1314	the benefits	1303:1314	the benefits of IMD	1303:1321	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	5	60	theme	barrier	1062:1068	arg1	function					1070:1077	the barrier function	1058:1077	the barrier function	1058:1077	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	3	61	from	%	512:512	arg1	IMD					504:506	IMD	504:506	IMD at 5% (w/v)	504:518	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	61	from	%	512:512	arg1	pre-treatment					487:499	pre-treatment	487:499	pre-treatment of IMD at 5% (w/v)	487:518	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	1	62	from	integrity	205:213	arg1	HFD					262:264	HFD	262:264	HFD	262:264	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	1	62	from	integrity	205:213	arg1	diet					256:259	a high-fat diet	245:259	a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model	245:340	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	3	63	theme	pro-inflammatory	566:581	arg1	MCP-1					600:604	MCP-1	600:604	MCP-1	600:604	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	63	theme	pro-inflammatory	566:581	arg1	IL-6					611:614	IL-6	611:614	IL-6	611:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	63	theme	pro-inflammatory	566:581	arg1	TNF-α					593:597	TNF-α	593:597	TNF-α	593:597	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	63	theme	pro-inflammatory	566:581	arg1	mediators					583:591	pro-inflammatory mediators	566:591	pro-inflammatory mediators TNF-α, MCP-1, and IL-6	566:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	6	64	theme	Bacteroides-Prevotella	1177:1198	arg1	growth					1167:1172	the growth	1163:1172	the growth of Bacteroides-Prevotella	1163:1198	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	10	65	theme	metabolic	2045:2053	arg1	disorders					2055:2063	metabolic disorders	2045:2063	metabolic disorders	2045:2063	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36041062	3	66	theme	endotoxin	552:560	arg1	concentration					535:547	the concentration	531:547	the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6	531:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	9	67	theme	strong	1776:1781	arg1	evidence					1783:1790	strong evidence	1776:1790	strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function	1776:1905	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	6	68	theme	energy	1354:1359	arg1	homeostasis					1361:1371	energy homeostasis	1354:1371	energy homeostasis	1354:1371	However, IMD supplementation was shown to restore the microbial diversity, promote the growth of Bacteroides-Prevotella, and upregulate the related d-glucarate and d-galactarate degradation pathways, together demonstrating the benefits of IMD as a prebiotic able to promote energy homeostasis.					
36041062	0	69	theme	LPS-Induced	73:83	arg1	Inflammation					103:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	1	70	theme	-induced	298:305	arg1	inflammation					317:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	7	71	from	profile	1419:1425	arg1	model					1481:1485	the low-grade inflammation mouse model	1448:1485	the low-grade inflammation mouse model	1448:1485	Our results also showed that the blood lipid profile and glucose level in the low-grade inflammation mouse model were modulated by IMD.					
36041062	0	72	from	Effect	11:16	arg1	Model					62:66	a High-Fat Diet Mouse Model	40:66	a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation	40:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	0	73	theme	Chronic	95:101	arg1	Inflammation					103:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	LPS-Induced Low-Grade Chronic Inflammation	73:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	0	74	theme	Isomaltodextrin	21:35	arg1	Effect					11:16	Regulatory Effect	0:16	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.	0:115	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	8	75	theme	metabolic	1566:1574	arg1	disorder					1576:1583	the metabolic disorder	1562:1583	the metabolic disorder	1562:1583	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	5	76	theme	dietary	978:984	arg1	factors					986:992	unhealthy dietary factors	968:992	unhealthy dietary factors	968:992	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	2	77	theme	syndromes	438:446	arg1	risk					409:412	the risk	405:412	the risk of developing metabolic syndromes	405:446	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	2	78	theme	response	373:380	arg1	homeostasis					347:357	The homeostasis	343:357	The homeostasis of the immune response	343:380	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	2	78	theme	response	373:380	arg1	important					385:393	important	385:393	important	385:393	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	0	79	theme	Diet	51:54	arg1	Model					62:66	a High-Fat Diet Mouse Model	40:66	a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation	40:114	Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation.					
36041062	5	80	located	observed	910:917	arg1	mice					922:925	mice	922:925	mice induced by HFD plus LPS	922:949	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	5	80	located	observed	910:917	arg2	dysbiosis					896:904	dysbiosis	896:904	dysbiosis	896:904	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	5	80	located	observed	910:917	arg1	addition					886:893	addition	886:893	addition	886:893	In addition, dysbiosis was observed in mice induced by HFD plus LPS, suggesting that unhealthy dietary factors elicit metabolic endotoxemia and associated dysbiosis to impair the barrier function.					
36041062	1	81	with	diet	256:259	arg1	inflammation					317:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	a lipopolysaccharide (LPS)-induced low-grade inflammation	272:328	This study aimed to identify the effects of isomaltodextrin (IMD) on sustaining the gut integrity and microbiota composition in a high-fat diet (HFD) with a lipopolysaccharide (LPS)-induced low-grade inflammation mouse model.					
36041062	2	82	theme	developing	417:426	arg1	syndromes					438:446	developing metabolic syndromes	417:446	developing metabolic syndromes	417:446	The homeostasis of the immune response is important to reduce the risk of developing metabolic syndromes.					
36041062	8	83	theme	immune	1599:1604	arg1	responses					1606:1614	immune responses	1599:1614	immune responses in inflamed white adipose tissues	1599:1648	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	4	84	theme	junction	794:801	arg1	expressions					811:821	the tight junction protein expressions	784:821	the tight junction protein expressions	784:821	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	8	85	theme	macrophage	1668:1677	arg1	infiltration					1679:1690	the macrophage infiltration	1664:1690	the macrophage infiltration	1664:1690	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	9	86	theme	microbiota	1863:1872	arg1	composition					1874:1884	a healthy gut microbiota composition	1849:1884	a healthy gut microbiota composition	1849:1884	These findings provide strong evidence for IMD to be a potential prebiotic that acts to sustain a healthy gut microbiota composition and barrier function.					
36041062	4	87	theme	intestinal	744:753	arg1	permeability					755:766	intestinal permeability	744:766	intestinal permeability	744:766	Subsequently, IMD supplementation maintained the structural integrity and intestinal permeability by upregulating the tight junction protein expressions, leading to reducing D-mannitol concentration in the blood.					
36041062	3	88	dep	mediators	583:591	arg1	MCP-1					600:604	MCP-1	600:604	MCP-1	600:604	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	88	dep	mediators	583:591	arg1	IL-6					611:614	IL-6	611:614	IL-6	611:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	88	dep	mediators	583:591	arg1	TNF-α					593:597	TNF-α	593:597	TNF-α	593:597	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	3	88	dep	mediators	583:591	arg1	mediators					583:591	pro-inflammatory mediators	566:591	pro-inflammatory mediators TNF-α, MCP-1, and IL-6	566:614	The results of this study showed that pre-treatment of IMD at 5% (w/v) suppressed the concentration of endotoxin and pro-inflammatory mediators TNF-α, MCP-1, and IL-6 while increasing the adiponectin level in the plasma.					
36041062	8	89	theme	white	1628:1632	arg1	tissues					1642:1648	inflamed white adipose tissues	1619:1648	inflamed white adipose tissues	1619:1648	Moreover, IMD supplementation effectively prevented the metabolic disorder and modulated immune responses in inflamed white adipose tissues by inhibiting the macrophage infiltration and restoring the adiponectin, PPAR-γ, and IRS-1 expression.					
36041062	10	90	theme	unhealthy	1933:1941	arg1	balance					1967:1973	an unhealthy diet-impaired metabolic balance	1930:1973	an unhealthy diet-impaired metabolic balance	1930:1973	By protecting against an unhealthy diet-impaired metabolic balance and maintaining immune homeostasis, IMD may affect the development of metabolic disorders.					
36563800	0	0	theme	composite	98:106	arg1	films					108:112	composite films	98:112	composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	98:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	2	1	theme	antimicrobial	438:450	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	0	2	theme	fillets	205:211	arg1	shelf-life					176:185	the shelf-life	172:185	the shelf-life of chicken breast fillets	172:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	6	3	theme	refrigerated	1095:1106	arg1	storage					1108:1114	refrigerated storage	1095:1114	refrigerated storage for 21 days	1095:1126	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	8	4	theme	TEO	1529:1531	arg1	nanoemulsion					1533:1544	TEO nanoemulsion	1529:1544	TEO nanoemulsion	1529:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	5	theme	products	1633:1640	arg1	shelf-life					1614:1623	the shelf-life	1610:1623	the shelf-life of food products	1610:1640	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	7	6	theme	samples	1224:1230	arg1	populations					1143:1153	The microbial populations	1129:1153	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO	1129:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	6	theme	samples	1224:1230	arg1	lower					1288:1292	lower	1288:1292	lower	1288:1292	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	0	7	theme	breast	198:203	arg1	fillets					205:211	chicken breast fillets	190:211	chicken breast fillets	190:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	2	8	theme	composite	466:474	arg1	films					476:480	composite films	466:480	composite films	466:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	7	9	theme	bacteria	1208:1215	arg1	populations					1143:1153	The microbial populations	1129:1153	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO	1129:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	9	theme	bacteria	1208:1215	arg1	lower					1288:1292	lower	1288:1292	lower	1288:1292	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	1	10	theme	polyvinyl	333:341	arg1	PVA					352:354	PVA	352:354	PVA	352:354	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	1	10	theme	polyvinyl	333:341	arg1	alcohol					343:349	polyvinyl alcohol	333:349	polyvinyl alcohol (PVA)	333:355	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	3	11	theme	infrared	515:522	arg1	FTIR					538:541	FTIR	538:541	FTIR	538:541	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	3	11	theme	infrared	515:522	arg1	spectroscopy					524:535	Fourier-transform infrared spectroscopy	497:535	Fourier-transform infrared spectroscopy (FTIR)	497:542	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	3	12	from	interactions	610:621	arg1	matrix					645:650	the composite film matrix	626:650	the composite film matrix	626:650	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	7	13	theme	total	1450:1454	arg1	count					1456:1460	the maximum acceptable total count	1427:1460	the maximum acceptable total count limit	1427:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	2	14	theme	films	476:480	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	7	15	theme	count	1456:1460	arg1	7 days					1397:1402	7 days	1397:1402	7 days which is considered as the maximum acceptable total count limit	1397:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	15	theme	count	1456:1460	arg1	limit					1462:1466	the maximum acceptable total count limit	1427:1466	the maximum acceptable total count limit	1427:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	16	theme	log	1381:1383	arg1	CFU/g					1385:1389	7 log CFU/g	1379:1389	7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit	1379:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	4	17	theme	moisture	751:758	arg1	content					760:766	moisture content	751:766	moisture content	751:766	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	5	18	theme	gram-negative	904:916	arg1	bacteria					936:943	gram-negative and gram-positive bacteria	904:943	gram-negative and gram-positive bacteria	904:943	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	4	19	theme	transparency	840:851	arg1	value					853:857	transparency value	840:857	transparency value	840:857	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	0	20	theme	thyme	125:129	arg1	nanoemulsion					145:156	thyme essential oil nanoemulsion	125:156	thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	125:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	7	21	theme	maximum	1431:1437	arg1	count					1456:1460	the maximum acceptable total count	1427:1460	the maximum acceptable total count limit	1427:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	2	22	theme	microstructural	418:432	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	3	23	theme	Fourier-transform	497:513	arg1	FTIR					538:541	FTIR	538:541	FTIR	538:541	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	3	23	theme	Fourier-transform	497:513	arg1	spectroscopy					524:535	Fourier-transform infrared spectroscopy	497:535	Fourier-transform infrared spectroscopy (FTIR)	497:542	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	8	24	contain	containing	1518:1527	arg1	films					1512:1516	AG/PVA/CS composite films	1492:1516	AG/PVA/CS composite films containing TEO nanoemulsion	1492:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	24	contain	containing	1518:1527	arg1	packaging					1589:1597	eco-friendly active food packaging	1564:1597	eco-friendly active food packaging	1564:1597	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	24	contain	containing	1518:1527	arg2	nanoemulsion					1533:1544	TEO nanoemulsion	1529:1544	TEO nanoemulsion	1529:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	0	25	theme	essential	131:139	arg1	nanoemulsion					145:156	thyme essential oil nanoemulsion	125:156	thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	125:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	7	26	theme	blank	1343:1347	arg1	samples					1349:1355	blank samples	1343:1355	blank samples	1343:1355	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	27	theme	acceptable	1439:1448	arg1	count					1456:1460	the maximum acceptable total count	1427:1460	the maximum acceptable total count limit	1427:1466	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	6	28	from	effect	991:996	arg1	properties					1034:1043	the microbiological properties	1014:1043	the microbiological properties of chicken breast fillets	1014:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	5	29	theme	gram-positive	922:934	arg1	bacteria					936:943	gram-negative and gram-positive bacteria	904:943	gram-negative and gram-positive bacteria	904:943	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	6	30	theme	fillets	1063:1069	arg1	properties					1034:1043	the microbiological properties	1014:1043	the microbiological properties of chicken breast fillets	1014:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	2	31	theme	mechanical	391:400	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	4	32	theme	light	816:820	arg1	transmittance					822:834	light transmittance	816:834	light transmittance	816:834	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	6	33	theme	breast	1056:1061	arg1	fillets					1063:1069	chicken breast fillets	1048:1069	chicken breast fillets	1048:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	1	34	theme	composite	291:299	arg1	films					301:305	composite films	291:305	composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS)	291:374	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	8	35	theme	active	1577:1582	arg1	films					1512:1516	AG/PVA/CS composite films	1492:1516	AG/PVA/CS composite films containing TEO nanoemulsion	1492:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	35	theme	active	1577:1582	arg1	packaging					1589:1597	eco-friendly active food packaging	1564:1597	eco-friendly active food packaging	1564:1597	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	36	theme	AG/PVA/CS	1492:1500	arg1	films					1512:1516	AG/PVA/CS composite films	1492:1516	AG/PVA/CS composite films containing TEO nanoemulsion	1492:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	36	theme	AG/PVA/CS	1492:1500	arg1	packaging					1589:1597	eco-friendly active food packaging	1564:1597	eco-friendly active food packaging	1564:1597	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	6	37	theme	chicken	1048:1054	arg1	fillets					1063:1069	chicken breast fillets	1048:1069	chicken breast fillets	1048:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	2	38	theme	physical	381:388	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	0	39	theme	oil	141:143	arg1	nanoemulsion					145:156	thyme essential oil nanoemulsion	125:156	thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	125:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	4	40	theme	composite	714:722	arg1	films					724:728	the composite films	710:728	the composite films	710:728	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	0	41	theme	antimicrobial	34:46	arg1	activity					48:55	antimicrobial activity	34:55	antimicrobial activity	34:55	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	2	42	dep	barrier	409:415	arg1	water					403:407	water	403:407	water	403:407	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	8	43	theme	food	1628:1631	arg1	products					1633:1640	food products	1628:1640	food products	1628:1640	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	3	44	theme	intermolecular	595:608	arg1	interactions					610:621	the intermolecular interactions	591:621	the intermolecular interactions in the composite film matrix	591:650	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	4	45	theme	vapor	779:783	arg1	permeability					785:796	water vapor permeability	773:796	water vapor permeability	773:796	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	1	46	theme	thyme	229:233	arg1	nanoemulsion					255:266	thyme essential oil (TEO) nanoemulsion	229:266	thyme essential oil (TEO) nanoemulsion	229:266	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	2	47	theme	barrier	409:415	arg1	properties					452:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties	377:461	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films	377:480	The physical, mechanical, water barrier, microstructural and antimicrobial properties of composite films were assessed.					
36563800	1	48	theme	almond	316:321	arg1	AG					328:329	AG	328:329	AG	328:329	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	1	48	theme	almond	316:321	arg1	gum					323:325	almond gum	316:325	almond gum (AG)	316:330	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	6	49	theme	microbiological	1018:1032	arg1	properties					1034:1043	the microbiological properties	1014:1043	the microbiological properties of chicken breast fillets	1014:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	3	50	theme	X-ray	548:552	arg1	XRD					567:569	XRD	567:569	XRD	567:569	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	3	50	theme	X-ray	548:552	arg1	diffraction					554:564	X-ray diffraction	548:564	X-ray diffraction (XRD) analysis	548:579	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	5	51	theme	films	890:894	arg1	activity					878:885	The antimicrobial activity	860:885	The antimicrobial activity of films against gram-negative and gram-positive bacteria	860:943	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	8	52	theme	composite	1502:1510	arg1	films					1512:1516	AG/PVA/CS composite films	1492:1516	AG/PVA/CS composite films containing TEO nanoemulsion	1492:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	52	theme	composite	1502:1510	arg1	packaging					1589:1597	eco-friendly active food packaging	1564:1597	eco-friendly active food packaging	1564:1597	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	7	53	theme	acid	1203:1206	arg1	bacteria					1208:1215	total mesophilic, psychrotrophic, and lactic acid bacteria	1158:1215	bacteria	1208:1215	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	8	54	theme	food	1584:1587	arg1	films					1512:1516	AG/PVA/CS composite films	1492:1516	AG/PVA/CS composite films containing TEO nanoemulsion	1492:1544	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	8	54	theme	food	1584:1587	arg1	packaging					1589:1597	eco-friendly active food packaging	1564:1597	eco-friendly active food packaging	1564:1597	Results disclosed that AG/PVA/CS composite films containing TEO nanoemulsion can be applied as eco-friendly active food packaging to enhance the shelf-life of food products.					
36563800	3	55	theme	diffraction	554:564	arg1	analysis					572:579	X-ray diffraction (XRD) analysis	548:579	X-ray diffraction (XRD) analysis	548:579	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	7	56	theme	microbial	1133:1141	arg1	populations					1143:1153	The microbial populations	1129:1153	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO	1129:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	56	theme	microbial	1133:1141	arg1	lower					1288:1292	lower	1288:1292	lower	1288:1292	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	0	57	theme	chicken	190:196	arg1	fillets					205:211	chicken breast fillets	190:211	chicken breast fillets	190:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	0	58	contain	containing	114:123	arg2	nanoemulsion					145:156	thyme essential oil nanoemulsion	125:156	thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	125:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	0	58	contain	containing	114:123	arg1	films					108:112	composite films	98:112	composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets	98:211	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	4	59	theme	TEO	701:703	arg1	incorporation					684:696	the incorporation	680:696	the incorporation of TEO into the composite films	680:728	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	1	60	theme	essential	235:243	arg1	nanoemulsion					255:266	thyme essential oil (TEO) nanoemulsion	229:266	thyme essential oil (TEO) nanoemulsion	229:266	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	5	61	theme	diffusion	969:977	arg1	method					979:984	a disc diffusion method	962:984	a disc diffusion method	962:984	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	3	62	theme	composite	630:638	arg1	matrix					645:650	the composite film matrix	626:650	the composite film matrix	626:650	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	5	63	theme	disc	964:967	arg1	method					979:984	a disc diffusion method	962:984	a disc diffusion method	962:984	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	7	64	theme	composite	1258:1266	arg1	TEO					1279:1281	the composite containing TEO	1254:1281	the composite containing TEO	1254:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	1	65	theme	oil	245:247	arg1	nanoemulsion					255:266	thyme essential oil (TEO) nanoemulsion	229:266	thyme essential oil (TEO) nanoemulsion	229:266	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36563800	0	66	theme	gum/polyvinyl	67:79	arg1	characterization					12:27	characterization	12:27	characterization	12:27	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	0	66	theme	gum/polyvinyl	67:79	arg1	Production					0:9	Production	0:9	Production	0:9	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	0	66	theme	gum/polyvinyl	67:79	arg1	activity					48:55	antimicrobial activity	34:55	antimicrobial activity	34:55	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	3	67	theme	film	640:643	arg1	matrix					645:650	the composite film matrix	626:650	the composite film matrix	626:650	Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the intermolecular interactions in the composite film matrix.					
36563800	4	68	theme	water	773:777	arg1	permeability					785:796	water vapor permeability	773:796	water vapor permeability	773:796	The results indicated that the incorporation of TEO into the composite films increased thickness, moisture content, and water vapor permeability, while it reduced light transmittance and transparency value.					
36563800	7	69	theme	permitted	1303:1311	arg1	limit					1313:1317	the permitted limit	1299:1317	the permitted limit after 21 days	1299:1331	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	6	70	theme	composite	1001:1009	arg1	effect					991:996	The effect	987:996	The effect of composite on the microbiological properties of chicken breast fillets	987:1069	The effect of composite on the microbiological properties of chicken breast fillets was investigated during refrigerated storage for 21 days.					
36563800	0	71	theme	almond	60:65	arg1	gum/polyvinyl					67:79	almond gum/polyvinyl	60:79	almond gum/polyvinyl	60:79	Production, characterization, and antimicrobial activity of almond gum/polyvinyl alcohol/chitosan composite films containing thyme essential oil nanoemulsion for extending the shelf-life of chicken breast fillets.					
36563800	7	72	theme	lactic	1196:1201	arg1	bacteria					1208:1215	total mesophilic, psychrotrophic, and lactic acid bacteria	1158:1215	bacteria	1208:1215	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	73	theme	psychrotrophic	1176:1189	arg1	populations					1143:1153	The microbial populations	1129:1153	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO	1129:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	73	theme	psychrotrophic	1176:1189	arg1	lower					1288:1292	lower	1288:1292	lower	1288:1292	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	7	74	theme	containing	1268:1277	arg1	TEO					1279:1281	the composite containing TEO	1254:1281	the composite containing TEO	1254:1281	The microbial populations of total mesophilic, psychrotrophic, and lactic acid bacteria of the samples that were coated with the composite containing TEO were lower than the permitted limit after 21 days while for blank samples they were higher than 7 log CFU/g after 7 days which is considered as the maximum acceptable total count limit.					
36563800	5	75	theme	antimicrobial	864:876	arg1	activity					878:885	The antimicrobial activity	860:885	The antimicrobial activity of films against gram-negative and gram-positive bacteria	860:943	The antimicrobial activity of films against gram-negative and gram-positive bacteria was tested using a disc diffusion method.					
36563800	1	76	theme	TEO	250:252	arg1	nanoemulsion					255:266	thyme essential oil (TEO) nanoemulsion	229:266	thyme essential oil (TEO) nanoemulsion	229:266	In this study, thyme essential oil (TEO) nanoemulsion was immobilized within composite films based on almond gum (AG), polyvinyl alcohol (PVA), and chitosan (CS).					
36087999	0	0	theme	photocatalytic	92:105	arg1	degradation					107:117	efficient photocatalytic degradation	82:117	efficient photocatalytic degradation	82:117	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	3	1	theme	cellulose-based	718:732	arg1	hydrogel					744:751	cellulose-based composite hydrogel	718:751	cellulose-based composite hydrogel	718:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	4	2	theme	light	886:890	arg1	irradiation					892:902	light irradiation	886:902	light irradiation	886:902	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	1	3	theme	water	180:184	arg1	remediation					186:196	water remediation	180:196	water remediation	180:196	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	4	4	theme	composite	923:931	arg1	hydrogel					933:940	cellulose-based composite hydrogel	907:940	cellulose-based composite hydrogel	907:940	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	4	5	from	ratio	978:982	arg1	120 min					954:960	120 min	954:960	120 min	954:960	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	0	6	theme	efficient	82:90	arg1	degradation					107:117	efficient photocatalytic degradation	82:117	efficient photocatalytic degradation	82:117	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	3	7	theme	mechanical	693:702	arg1	properties					704:713	the mechanical properties	689:713	the mechanical properties of cellulose-based composite hydrogel	689:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	2	8	theme	oxide	332:336	arg1	heterojunctions					358:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	9	theme	SiO2	352:355	arg1	heterojunctions					358:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	0	10	theme	ZnO/SiO2	53:60	arg1	heterojunctions					62:76	ZnO/SiO2 heterojunctions	53:76	ZnO/SiO2 heterojunctions	53:76	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	5	11	theme	new	1105:1107	arg1	hydrogel					1109:1116	new hydrogel supports	1105:1125	new hydrogel supports	1105:1125	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	2	12	theme	zinc	327:330	arg1	oxide					332:336	zinc oxide	327:336	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	12	theme	zinc	327:330	arg1	ZnO					339:341	ZnO	339:341	ZnO	339:341	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	4	13	theme	removal	970:976	arg1	ratio					978:982	the removal ratio	966:982	the removal ratio maintained as high as 90 % after eight degradation cycles	966:1040	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	3	14	theme	composite	734:742	arg1	hydrogel					744:751	cellulose-based composite hydrogel	718:751	cellulose-based composite hydrogel	718:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	4	15	theme	blue	870:873	arg1	MB					876:877	MB	876:877	MB	876:877	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	4	15	theme	blue	870:873	arg1	methylene					860:868	methylene blue	860:873	methylene blue (MB) under light irradiation	860:902	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	3	16	theme	compressive	785:795	arg1	strength					797:804	a high compressive strength	778:804	a high compressive strength of 703.4 kPa	778:817	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	3	17	theme	hydrogel	744:751	arg1	properties					704:713	the mechanical properties	689:713	the mechanical properties of cellulose-based composite hydrogel	689:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	1	18	theme	compromised	211:221	arg1	activity					233:240	compromised catalytic activity	211:240	compromised catalytic activity	211:240	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	4	19	theme	degradation	1023:1033	arg1	cycles					1035:1040	eight degradation cycles	1017:1040	eight degradation cycles	1017:1040	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	2	20	theme	surface	632:638	arg1	state					640:644	its surface state	628:644	its surface state	628:644	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	21	theme	/silica	343:349	arg1	heterojunctions					358:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	1	22	theme	catalytic	223:231	arg1	activity					233:240	compromised catalytic activity	211:240	compromised catalytic activity	211:240	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	0	23	theme	robust	22:27	arg1	hydrogel					39:46	a robust cellulose hydrogel	20:46	a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation	20:117	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	3	24	theme	high	780:783	arg1	strength					797:804	a high compressive strength	778:804	a high compressive strength of 703.4 kPa	778:817	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	2	25	theme	ZnO	576:578	arg1	SiO2					418:421	SiO2	418:421	SiO2	418:421	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	25	theme	ZnO	576:578	arg1	properties					562:571	the photocatalytic properties	543:571	the photocatalytic properties of ZnO	543:578	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	25	theme	ZnO	576:578	arg1	agent					457:461	a cross-linking agent	441:461	a cross-linking agent	441:461	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	26	theme	cross-linking	443:455	arg1	SiO2					418:421	SiO2	418:421	SiO2	418:421	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	26	theme	cross-linking	443:455	arg1	agent					457:461	a cross-linking agent	441:461	a cross-linking agent	441:461	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	26	theme	cross-linking	443:455	arg1	properties					562:571	the photocatalytic properties	543:571	the photocatalytic properties of ZnO	543:578	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	5	27	theme	high	1132:1135	arg1	stability					1137:1145	high stability	1132:1145	high stability	1132:1145	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	5	28	theme	facile	1078:1083	arg1	method					1085:1090	a low-cost and facile method	1063:1090	a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties	1063:1185	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	1	29	theme	insufficient	246:257	arg1	stability					259:267	insufficient stability	246:267	insufficient stability	246:267	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	0	30	theme	cellulose	29:37	arg1	hydrogel					39:46	a robust cellulose hydrogel	20:46	a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation	20:117	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	5	31	theme	efficient	1151:1159	arg1	properties					1176:1185	efficient photocatalytic properties	1151:1185	efficient photocatalytic properties	1151:1185	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	2	32	theme	photocatalytic	547:560	arg1	SiO2					418:421	SiO2	418:421	SiO2	418:421	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	32	theme	photocatalytic	547:560	arg1	properties					562:571	the photocatalytic properties	543:571	the photocatalytic properties of ZnO	543:578	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	32	theme	photocatalytic	547:560	arg1	agent					457:461	a cross-linking agent	441:461	a cross-linking agent	441:461	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	4	33	from	%	949:949	arg1	120 min					954:960	120 min	954:960	120 min	954:960	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	4	34	theme	degradation	834:844	arg1	efficiency					846:855	the degradation efficiency	830:855	the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel	830:940	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	4	34	theme	degradation	834:844	arg1	%					949:949	95 %	946:949	95 % in 120 min	946:960	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	2	35	theme	mechanical	478:487	arg1	strength					489:496	the mechanical strength	474:496	the mechanical strength	474:496	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	3	36	theme	703.4 kPa	809:817	arg1	strength					797:804	a high compressive strength	778:804	a high compressive strength of 703.4 kPa	778:817	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	2	37	theme	electron-hole	601:613	arg1	pairs					615:619	the electron-hole pairs	597:619	the electron-hole pairs	597:619	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	3	38	from	improvement	674:684	arg1	properties					704:713	the mechanical properties	689:713	the mechanical properties of cellulose-based composite hydrogel	689:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	4	39	theme	methylene	860:868	arg1	efficiency					846:855	the degradation efficiency	830:855	the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel	830:940	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	4	39	theme	methylene	860:868	arg1	%					949:949	95 %	946:949	95 % in 120 min	946:960	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	2	40	with	hydrogel	313:320	arg1	heterojunctions					358:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	zinc oxide (ZnO)/silica (SiO2) heterojunctions	327:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	4	41	theme	cellulose-based	907:921	arg1	hydrogel					933:940	cellulose-based composite hydrogel	907:940	cellulose-based composite hydrogel	907:940	Moreover, the degradation efficiency of methylene blue (MB) under light irradiation by cellulose-based composite hydrogel was 95 % in 120 min and the removal ratio maintained as high as 90 % after eight degradation cycles.					
36087999	3	42	theme	significant	662:672	arg1	improvement					674:684	a significant improvement	660:684	a significant improvement in the mechanical properties of cellulose-based composite hydrogel	660:751	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	3	42	theme	significant	662:672	arg1	result					652:657	a result	650:657	a result	650:657	As a result, a significant improvement in the mechanical properties of cellulose-based composite hydrogel was achieved, exhibiting a high compressive strength of 703.4 kPa.					
36087999	2	43	theme	composite	303:311	arg1	hydrogel					313:320	a robust cellulose-based composite hydrogel	278:320	a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions	278:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	1	44	theme	efficient	157:165	arg1	photocatalyst					139:151	photocatalyst	139:151	photocatalyst	139:151	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	1	44	theme	efficient	157:165	arg1	strategy					167:174	an efficient strategy	154:174	an efficient strategy for water remediation	154:196	Hydrogel supported photocatalyst, an efficient strategy for water remediation suffers from compromised catalytic activity and insufficient stability.					
36087999	5	45	theme	low-cost	1065:1072	arg1	method					1085:1090	a low-cost and facile method	1063:1090	a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties	1063:1185	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	2	46	theme	cellulose-based	287:301	arg1	hydrogel					313:320	a robust cellulose-based composite hydrogel	278:320	a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions	278:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	5	47	dep	hydrogel	1109:1116	arg1	supports					1118:1125	supports	1118:1125	supports	1118:1125	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36087999	2	48	theme	hydrogel	515:522	arg1	stability					502:510	stability	502:510	stability	502:510	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	48	theme	hydrogel	515:522	arg1	strength					489:496	the mechanical strength	474:496	the mechanical strength	474:496	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	2	49	theme	robust	280:285	arg1	hydrogel					313:320	a robust cellulose-based composite hydrogel	278:320	a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions	278:372	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	0	50	with	hydrogel	39:46	arg1	heterojunctions					62:76	ZnO/SiO2 heterojunctions	53:76	ZnO/SiO2 heterojunctions	53:76	In-situ structuring a robust cellulose hydrogel with ZnO/SiO2 heterojunctions for efficient photocatalytic degradation.					
36087999	2	51	theme	in-situ	393:399	arg1	synthesis					401:409	in-situ synthesis	393:409	in-situ synthesis	393:409	Herein, a robust cellulose-based composite hydrogel with zinc oxide (ZnO)/silica (SiO2) heterojunctions were fabricated by in-situ synthesis, where SiO2 not only acted as a cross-linking agent to enhance the mechanical strength and stability of hydrogel, but also promoted the photocatalytic properties of ZnO via transferring the electron-hole pairs due to its surface state.					
36087999	5	52	theme	photocatalytic	1161:1174	arg1	properties					1176:1185	efficient photocatalytic properties	1151:1185	efficient photocatalytic properties	1151:1185	This study provides a low-cost and facile method to construct new hydrogel supports with high stability and efficient photocatalytic properties.					
36219927	1	0	theme	host	279:282	arg1	health					284:289	the host health	275:289	the host health	275:289	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	4	1	theme	copra	895:899	arg1	pathway					954:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway	891:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083	891:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	7	2	theme	GH1	1437:1439	arg1	β-glucosidase					1441:1453	GH1 β-glucosidase	1437:1453	GH1 β-glucosidase	1437:1453	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	3	3	from	meal	664:667	arg1	β-manno-oligosaccharides					584:607	β-manno-oligosaccharides	584:607	β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601)	584:717	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	3	4	theme	DSMZ	562:565	arg1	20083					567:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	6	5	theme	fermentation	1178:1189	arg1	media					1191:1195	the fermentation media	1174:1195	the fermentation media	1174:1195	CM-β-MOS having DP2-3 were found to deplete from the fermentation media.					
36219927	9	6	theme	first	1786:1790	arg1	This					1774:1777	This	1774:1777	This	1774:1777	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	9	6	theme	first	1786:1790	arg1	study					1792:1796	the first study	1782:1796	the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides	1782:1912	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	3	7	theme	guar	614:617	arg1	gum					619:621	guar gum	614:621	guar gum	614:621	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	4	8	theme	utilisation	942:952	arg1	pathway					954:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway	891:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083	891:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	1	9	theme	gut	246:248	arg1	microbiota					250:259	human gut microbiota	240:259	human gut microbiota	240:259	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	7	10	theme	linear	1400:1405	arg1	CM-β-MOS					1407:1414	DP ≥ 3 linear CM-β-MOS	1393:1414	DP ≥ 3 linear CM-β-MOS	1393:1414	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	4	11	dep	B.	965:966	arg1	adolescentis					968:979	adolescentis	968:979	adolescentis	968:979	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	3	12	theme	bean	631:634	arg1	gum					636:638	locust bean gum	624:638	locust bean gum	624:638	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	4	13	theme	β-manno-oligosaccharides	906:929	arg1	pathway					954:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway	891:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083	891:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	4	14	theme	CM-β-MOS	932:939	arg1	pathway					954:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway	891:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083	891:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	0	15	from	analysis	132:139	arg1	DSMZ					92:95	DSMZ	92:95	DSMZ	92:95	Insights into β-manno-oligosaccharide uptake and metabolism in Bifidobacterium adolescentis DSMZ 20083 from whole-genome microarray analysis.					
36219927	3	16	theme	20083	567:571	arg1	ability					505:511	the ability	501:511	the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601)	501:717	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	1	17	theme	dietary	171:177	arg1	glycans					179:185	non-digestible dietary glycans	156:185	non-digestible dietary glycans	156:185	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	6	18	contain	having	1134:1139	arg1	CM-β-MOS					1125:1132	CM-β-MOS	1125:1132	CM-β-MOS having DP2-3	1125:1145	CM-β-MOS having DP2-3 were found to deplete from the fermentation media.					
36219927	6	18	contain	having	1134:1139	arg2	DP2-3					1141:1145	DP2-3	1141:1145	DP2-3	1141:1145	CM-β-MOS having DP2-3 were found to deplete from the fermentation media.					
36219927	8	19	dep	found	1721:1725	arg1	up-regulated					1727:1738	up-regulated	1727:1738	up-regulated following the growth on CM-β-MOS	1727:1771	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	9	20	theme	molecular	1820:1828	arg1	determinants					1830:1841	possible molecular determinants	1811:1841	possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides	1811:1912	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	7	21	theme	molecular	1248:1256	arg1	studies					1266:1272	molecular docking studies	1248:1272	molecular docking studies	1248:1272	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	0	22	from	Insights	0:7	arg1	adolescentis					79:90	Bifidobacterium adolescentis	63:90	Bifidobacterium adolescentis	63:90	Insights into β-manno-oligosaccharide uptake and metabolism in Bifidobacterium adolescentis DSMZ 20083 from whole-genome microarray analysis.					
36219927	0	23	theme	whole-genome	108:119	arg1	analysis					132:139	whole-genome microarray analysis	108:139	whole-genome microarray analysis	108:139	Insights into β-manno-oligosaccharide uptake and metabolism in Bifidobacterium adolescentis DSMZ 20083 from whole-genome microarray analysis.					
36219927	5	24	theme	B.	993:994	arg1	20083					1014:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	9	25	theme	B.	1851:1852	arg1	20083					1872:1876	B. adolescentis DSMZ 20083	1851:1876	B. adolescentis DSMZ 20083	1851:1876	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	8	26	theme	utilisation	1561:1571	arg1	pathways					1573:1580	utilisation pathways	1561:1580	utilisation pathways	1561:1580	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	5	27	theme	DSMZ	1009:1012	arg1	20083					1014:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	9	28	theme	DSMZ	1867:1870	arg1	20083					1872:1876	B. adolescentis DSMZ 20083	1851:1876	B. adolescentis DSMZ 20083	1851:1876	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	3	29	from	root	648:651	arg1	β-manno-oligosaccharides					584:607	β-manno-oligosaccharides	584:607	β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601)	584:717	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	2	30	theme	processed	401:409	arg1	foods					411:415	processed foods	401:415	processed foods	401:415	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	7	31	theme	transcriptome	1211:1223	arg1	analysis					1225:1232	Whole-genome transcriptome analysis	1198:1232	Whole-genome transcriptome analysis	1198:1232	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	8	32	theme	shunt	1589:1593	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	4	33	theme	underlying	755:764	arg1	mechanism					776:784	the underlying molecular mechanism	751:784	the underlying molecular mechanism	751:784	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	0	34	theme	β-manno-oligosaccharide	14:36	arg1	uptake					38:43	β-manno-oligosaccharide uptake	14:43	β-manno-oligosaccharide uptake	14:43	Insights into β-manno-oligosaccharide uptake and metabolism in Bifidobacterium adolescentis DSMZ 20083 from whole-genome microarray analysis.					
36219927	7	35	dep	B.	1292:1293	arg1	adolescentis					1295:1306	adolescentis	1295:1306	adolescentis	1295:1306	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	3	36	theme	present	425:431	arg1	study					433:437	the present study	421:437	the present study	421:437	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	8	37	theme	ABC	1596:1598	arg1	system					1610:1615	ABC transport system	1596:1615	ABC transport system	1596:1615	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	3	38	dep	in	440:441	arg1	vitro					443:447	vitro	443:447	vitro	443:447	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	7	39	theme	&	1324:1324	arg1	transporters					1330:1341	ABC & MFS transporters	1320:1341	ABC & MFS transporters	1320:1341	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	8	40	theme	system	1610:1615	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	4	41	theme	molecular	836:844	arg1	studies					854:860	molecular docking studies	836:860	molecular docking studies	836:860	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	8	42	theme	pyruvate	1618:1625	arg1	metabolism					1627:1636	pyruvate metabolism	1618:1636	pyruvate metabolism	1618:1636	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	10	43	theme	nutraceutical	1961:1973	arg1	industries					1975:1984	food and nutraceutical industries	1952:1984	food and nutraceutical industries	1952:1984	Our studies can prove resourceful to food and nutraceutical industries, aiming at precision microbiome modulation using β-manno-oligosaccharides.					
36219927	4	44	theme	microarray	802:811	arg1	analysis					813:820	a whole-genome microarray analysis	787:820	a whole-genome microarray analysis	787:820	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	9	45	theme	adolescentis	1854:1865	arg1	20083					1872:1876	B. adolescentis DSMZ 20083	1851:1876	B. adolescentis DSMZ 20083	1851:1876	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	7	46	theme	DSMZ	1308:1311	arg1	20083					1313:1317	B. adolescentis DSMZ 20083	1292:1317	B. adolescentis DSMZ 20083	1292:1317	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	10	47	theme	food	1952:1955	arg1	industries					1975:1984	food and nutraceutical industries	1952:1984	food and nutraceutical industries	1952:1984	Our studies can prove resourceful to food and nutraceutical industries, aiming at precision microbiome modulation using β-manno-oligosaccharides.					
36219927	3	48	theme	adult-associated	516:531	arg1	20083					567:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	7	49	theme	B.	1292:1293	arg1	20083					1313:1317	B. adolescentis DSMZ 20083	1292:1317	B. adolescentis DSMZ 20083	1292:1317	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	7	50	theme	linear	1502:1507	arg1	CM-β-MOS					1509:1516	linear CM-β-MOS	1502:1516	linear CM-β-MOS	1502:1516	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	1	51	dep	structure	211:219	arg1	the					207:209	the	207:209	the	207:209	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	2	52	theme	integral	310:317	arg1	component					319:327	an integral component	307:327	an integral component of the modern diet	307:346	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	2	52	theme	integral	310:317	arg1	additives					388:396	additives	388:396	additives	388:396	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	8	53	theme	glucouronate	1680:1691	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	3	54	theme	adolescentis	549:560	arg1	20083					567:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	7	55	theme	GH32	1460:1463	arg1	β-fructofuranosidase					1465:1484	GH32 β-fructofuranosidase	1460:1484	GH32 β-fructofuranosidase	1460:1484	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	4	56	theme	docking	846:852	arg1	studies					854:860	molecular docking studies	836:860	molecular docking studies	836:860	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	2	57	from	fibre	379:383	arg1	foods					411:415	processed foods	401:415	processed foods	401:415	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	5	58	dep	0.8	1054:1056	arg1	to					1051:1052	to	1051:1052	to	1051:1052	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	10	59	theme	microbiome	2007:2016	arg1	modulation					2018:2027	precision microbiome modulation	1997:2027	precision microbiome modulation using β-manno-oligosaccharides	1997:2058	Our studies can prove resourceful to food and nutraceutical industries, aiming at precision microbiome modulation using β-manno-oligosaccharides.					
36219927	2	60	theme	modern	336:341	arg1	diet					343:346	the modern diet	332:346	the modern diet	332:346	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	1	61	from	health	284:289	arg1	turn					269:272	turn	269:272	turn	269:272	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	1	62	theme	human	240:244	arg1	microbiota					250:259	human gut microbiota	240:259	human gut microbiota	240:259	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	4	63	from	pathway	954:960	arg1	20083					986:990	B. adolescentis DSMZ 20083	965:990	B. adolescentis DSMZ 20083	965:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	3	64	theme	locust	624:629	arg1	gum					636:638	locust bean gum	624:638	locust bean gum	624:638	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	1	65	theme	microbiota	250:259	arg1	composition					225:235	composition	225:235	composition	225:235	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	1	65	theme	microbiota	250:259	arg1	structure					211:219	structure	211:219	structure	211:219	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	7	66	theme	CM-β-MOS	1407:1414	arg1	uptake					1372:1377	the uptake	1368:1377	the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively	1368:1428	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	5	67	dep	grew	1020:1023	arg1	O.D600 nm					1038:1046	O.D600 nm up to 0.8	1038:1056	O.D600 nm up to 0.8	1038:1056	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	8	68	theme	absorption	1546:1555	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	4	69	theme	meal	901:904	arg1	pathway					954:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway	891:960	the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083	891:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	7	70	theme	DP ≥ 3	1393:1398	arg1	CM-β-MOS					1407:1414	DP ≥ 3 linear CM-β-MOS	1393:1414	DP ≥ 3 linear CM-β-MOS	1393:1414	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	3	71	theme	konjac	641:646	arg1	root					648:651	konjac root	641:651	konjac root	641:651	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	1	72	theme	non-digestible	156:169	arg1	glycans					179:185	non-digestible dietary glycans	156:185	non-digestible dietary glycans	156:185	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	7	73	theme	DP ≥ 2	1382:1387	arg1	uptake					1372:1377	the uptake	1368:1377	the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively	1368:1428	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	7	74	theme	docking	1258:1264	arg1	studies					1266:1272	molecular docking studies	1248:1272	molecular docking studies	1248:1272	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	5	75	theme	tested	1066:1071	arg1	β-manno-oligosaccharides					1073:1096	all tested β-manno-oligosaccharides	1062:1096	all tested β-manno-oligosaccharides	1062:1096	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	1	76	theme	glycans	179:185	arg1	Metabolism					142:151	Metabolism	142:151	Metabolism of non-digestible dietary glycans	142:185	Metabolism of non-digestible dietary glycans directly influences the structure and composition of human gut microbiota and, in turn, the host health.					
36219927	9	77	theme	possible	1811:1818	arg1	determinants					1830:1841	possible molecular determinants	1811:1841	possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides	1811:1912	This is the first study reporting on possible molecular determinants used by B. adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides.					
36219927	8	78	theme	Sugar	1540:1544	arg1	absorption					1546:1555	Sugar absorption	1540:1555	Sugar absorption	1540:1555	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	0	79	theme	microarray	121:130	arg1	analysis					132:139	whole-genome microarray analysis	108:139	whole-genome microarray analysis	108:139	Insights into β-manno-oligosaccharide uptake and metabolism in Bifidobacterium adolescentis DSMZ 20083 from whole-genome microarray analysis.					
36219927	4	80	theme	B.	965:966	arg1	20083					986:990	B. adolescentis DSMZ 20083	965:990	B. adolescentis DSMZ 20083	965:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	8	81	theme	pathways	1573:1580	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	4	82	theme	molecular	766:774	arg1	mechanism					776:784	the underlying molecular mechanism	751:784	the underlying molecular mechanism	751:784	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	3	83	from	gum	636:638	arg1	β-manno-oligosaccharides					584:607	β-manno-oligosaccharides	584:607	β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601)	584:717	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	5	84	theme	adolescentis	996:1007	arg1	20083					1014:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083	993:1018	B. adolescentis DSMZ 20083 grew appreciably (O.D600 nm up to 0.8) on all tested β-manno-oligosaccharides but maximally on CM-β-MOS.					
36219927	4	85	theme	DSMZ	981:984	arg1	20083					986:990	B. adolescentis DSMZ 20083	965:990	B. adolescentis DSMZ 20083	965:990	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	8	86	theme	Bifid	1583:1587	arg1	shunt					1589:1593	Bifid shunt	1583:1593	Bifid shunt	1583:1593	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	7	87	theme	Whole-genome	1198:1209	arg1	analysis					1225:1232	Whole-genome transcriptome analysis	1198:1232	Whole-genome transcriptome analysis	1198:1232	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	8	88	from	growth	1754:1759	arg1	CM-β-MOS					1764:1771	CM-β-MOS	1764:1771	CM-β-MOS	1764:1771	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	3	89	from	gum	619:621	arg1	β-manno-oligosaccharides					584:607	β-manno-oligosaccharides	584:607	β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601)	584:717	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	3	90	theme	in	440:441	arg1	fermentation					449:460	in vitro fermentation and TLC studies	440:476	fermentation	449:460	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	7	91	theme	MFS	1326:1328	arg1	transporters					1330:1341	ABC & MFS transporters	1320:1341	ABC & MFS transporters	1320:1341	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	8	92	theme	transport	1600:1608	arg1	system					1610:1615	ABC transport system	1596:1615	ABC transport system	1596:1615	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	3	93	theme	copra	658:662	arg1	meal					664:667	copra meal	658:667	copra meal	658:667	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	7	94	theme	ABC	1320:1322	arg1	transporters					1330:1341	ABC & MFS transporters	1320:1341	ABC & MFS transporters	1320:1341	Whole-genome transcriptome analysis, RT-qPCR, and molecular docking studies suggested that in B. adolescentis DSMZ 20083, ABC & MFS transporters are possibly involved in the uptake of DP ≥ 2 and DP ≥ 3 linear CM-β-MOS, respectively, while GH1 β-glucosidase, and GH32 β-fructofuranosidase possibly cleave linear CM-β-MOS into monosaccharides.					
36219927	3	95	used	used	483:486	arg2	studies					470:476	in vitro fermentation and TLC studies	440:476	studies	470:476	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	3	95	used	used	483:486	arg2	fermentation					449:460	in vitro fermentation and TLC studies	440:476	fermentation	449:460	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	3	96	theme	TLC	466:468	arg1	studies					470:476	in vitro fermentation and TLC studies	440:476	studies	470:476	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36219927	8	97	theme	metabolism	1627:1636	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	2	98	from	foods	411:415	arg1	fibre					379:383	fibre	379:383	fibre	379:383	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	8	99	theme	glycolysis/gluconeogenesis	1639:1664	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	4	100	theme	whole-genome	789:800	arg1	analysis					813:820	a whole-genome microarray analysis	787:820	a whole-genome microarray analysis	787:820	Further, to gain insights into the underlying molecular mechanism, a whole-genome microarray analysis, RT-qPCR, and molecular docking studies were employed to reconstruct the copra meal β-manno-oligosaccharides (CM-β-MOS) utilisation pathway in B. adolescentis DSMZ 20083.					
36219927	2	101	theme	diet	343:346	arg1	component					319:327	an integral component	307:327	an integral component of the modern diet	307:346	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	2	101	theme	diet	343:346	arg1	additives					388:396	additives	388:396	additives	388:396	β-Mannans form an integral component of the modern diet as naturally occurring dietary fibre or additives in processed foods.					
36219927	8	102	theme	pentose	1667:1673	arg1	inter-conversions					1693:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions	1540:1709	Sugar absorption and utilisation pathways; Bifid shunt, ABC transport system, pyruvate metabolism, glycolysis/gluconeogenesis, pentose, and glucouronate inter-conversions were also found up-regulated following the growth on CM-β-MOS.					
36219927	10	103	theme	precision	1997:2005	arg1	modulation					2018:2027	precision microbiome modulation	1997:2027	precision microbiome modulation using β-manno-oligosaccharides	1997:2058	Our studies can prove resourceful to food and nutraceutical industries, aiming at precision microbiome modulation using β-manno-oligosaccharides.					
36219927	3	104	theme	Bifidobacterium	533:547	arg1	20083					567:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	adult-associated Bifidobacterium adolescentis DSMZ 20083	516:571	In the present study, in vitro fermentation and TLC studies were used to determine the ability of adult-associated Bifidobacterium adolescentis DSMZ 20083 to utilise β-manno-oligosaccharides from guar gum, locust bean gum, konjac root, and copra meal generated using GH26 endo-β-mannanase (ManB-1601).					
36503750	0	0	from	adsorption	14:23	arg1	utilization					86:96	its consequential utilization	68:96	its consequential utilization as battery anode	68:113	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	0	0	from	adsorption	14:23	arg1	composite					54:62	biomass-based composite	40:62	biomass-based composite	40:62	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	0	1	theme	consequential	72:84	arg1	utilization					86:96	its consequential utilization	68:96	its consequential utilization as battery anode	68:113	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	4	2	theme	EDTA	713:716	arg1	moiety					718:723	the EDTA moiety	709:723	the EDTA moiety	709:723	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	1	3	from	pollutant	150:158	arg1	water					163:167	water	163:167	water	163:167	Antimony is more than an emerging pollutant in water but a scare resource.					
36503750	2	4	from	view	279:282	arg1	capacity					245:252	the record capacity	234:252	the record capacity so far from the balanced view of Sb(III) and Sb(V)	234:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36503750	0	5	theme	battery	101:107	arg1	anode					109:113	battery anode	101:113	battery anode	101:113	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	6	6	theme	electric	1037:1044	arg1	storage					1053:1059	electric energy storage	1037:1059	electric energy storage	1037:1059	This article provides a new idea for connecting water treatment and electric energy storage.					
36503750	6	7	theme	water	1017:1021	arg1	treatment					1023:1031	water treatment	1017:1031	water treatment	1017:1031	This article provides a new idea for connecting water treatment and electric energy storage.					
36503750	6	8	theme	new	993:995	arg1	idea					997:1000	a new idea	991:1000	a new idea for connecting water treatment and electric energy storage	991:1059	This article provides a new idea for connecting water treatment and electric energy storage.					
36503750	5	9	contain	contains	836:843	arg2	nanoparticles					889:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	9	contain	contains	836:843	arg1	600-FCSE-Sb					904:914	600-FCSE-Sb	904:914	600-FCSE-Sb	904:914	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	9	contain	contains	836:843	arg1	adsorbent					821:829	adsorbent	821:829	adsorbent	821:829	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	10	theme	adsorption	769:778	arg1	capacity					780:787	the ultra-high adsorption capacity	754:787	the ultra-high adsorption capacity of the adsorbent	754:804	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	11	theme	Li-ion	931:936	arg1	anode					946:950	Li-ion battery anode	931:950	Li-ion battery anode	931:950	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	12	theme	ultra-high	758:767	arg1	capacity					780:787	the ultra-high adsorption capacity	754:787	the ultra-high adsorption capacity of the adsorbent	754:804	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	3	13	theme	hollow	362:367	arg1	nanosphere					375:384	hollow Fe3O4 nanosphere	362:384	hollow Fe3O4 nanosphere	362:384	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	4	14	from	complex	696:702	arg1	adsorbent					732:740	adsorbent	732:740	adsorbent	732:740	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	4	15	theme	sphere	689:694	arg1	complex					696:702	the inner sphere complex	679:702	the inner sphere complex with the EDTA moiety in the adsorbent	679:740	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	2	16	theme	record	238:243	arg1	capacity					245:252	the record capacity	234:252	the record capacity so far from the balanced view of Sb(III) and Sb(V)	234:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36503750	3	17	theme	Fe3O4	369:373	arg1	nanosphere					375:384	hollow Fe3O4 nanosphere	362:384	hollow Fe3O4 nanosphere	362:384	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	0	18	theme	capacity	5:12	arg1	adsorption					14:23	High capacity adsorption	0:23	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.	0:114	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	3	19	theme	adsorption	439:448	arg1	capacity					450:457	superhigh adsorption capacity	429:457	superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively	429:526	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	5	20	theme	abundant	845:852	arg1	nanoparticles					889:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	21	theme	capacity	780:787	arg1	view					746:749	view	746:749	view of the ultra-high adsorption capacity of the adsorbent	746:804	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	0	22	theme	High	0:3	arg1	adsorption					14:23	High capacity adsorption	0:23	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.	0:114	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	2	23	theme	balanced	270:277	arg1	view					279:282	the balanced view	266:282	the balanced view of Sb(III) and Sb(V)	266:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36503750	1	24	theme	scare	175:179	arg1	resource					181:188	a scare resource	173:188	a scare resource	173:188	Antimony is more than an emerging pollutant in water but a scare resource.					
36503750	4	25	with	chitosan	632:639	arg1	bond					655:658	hydrogen bond	646:658	hydrogen bond	646:658	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	3	26	theme	mg/g	472:475	arg1	capacity					450:457	superhigh adsorption capacity	429:457	superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively	429:526	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	5	27	dep	abundant	845:852	arg1	%					860:860	>36.4%	855:860	>36.4%	855:860	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	28	theme	adsorbent	796:804	arg1	capacity					780:787	the ultra-high adsorption capacity	754:787	the ultra-high adsorption capacity of the adsorbent	754:804	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	3	29	theme	EDTA	395:398	arg1	chitosan					408:415	the EDTA grafted chitosan	391:415	the EDTA grafted chitosan	391:415	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	4	30	with	complex	696:702	arg1	moiety					718:723	the EDTA moiety	709:723	the EDTA moiety	709:723	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	4	31	theme	mechanism	533:541	arg1	study					543:547	The mechanism study	529:547	The mechanism study	529:547	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	0	32	theme	antimony	28:35	arg1	adsorption					14:23	High capacity adsorption	0:23	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.	0:114	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	2	33	with	adsorbent	219:227	arg1	capacity					245:252	the record capacity	234:252	the record capacity so far from the balanced view of Sb(III) and Sb(V)	234:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36503750	4	34	theme	inner	683:687	arg1	complex					696:702	the inner sphere complex	679:702	the inner sphere complex with the EDTA moiety in the adsorbent	679:740	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	5	35	theme	battery	938:944	arg1	anode					946:950	Li-ion battery anode	931:950	Li-ion battery anode	931:950	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	4	36	theme	Sb	580:581	arg1	adsorption					566:575	the adsorption	562:575	the adsorption of Sb	562:581	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	0	37	theme	biomass-based	40:52	arg1	composite					54:62	biomass-based composite	40:62	biomass-based composite	40:62	High capacity adsorption of antimony in biomass-based composite and its consequential utilization as battery anode.					
36503750	5	38	theme	dispersed	870:878	arg1	nanoparticles					889:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	5	39	theme	antimony	880:887	arg1	nanoparticles					889:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	abundant (>36.4%) highly dispersed antimony nanoparticles	845:901	In view of the ultra-high adsorption capacity of the adsorbent, the recovered adsorbent that contains abundant (>36.4%) highly dispersed antimony nanoparticles (600-FCSE-Sb) is applied to Li-ion battery anode after reduction.					
36503750	6	40	theme	energy	1046:1051	arg1	storage					1053:1059	electric energy storage	1037:1059	electric energy storage	1037:1059	This article provides a new idea for connecting water treatment and electric energy storage.					
36503750	2	41	theme	Sb	287:288	arg1	view					279:282	the balanced view	266:282	the balanced view of Sb(III) and Sb(V)	266:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36503750	4	42	theme	hydrogen	646:653	arg1	bond					655:658	hydrogen bond	646:658	hydrogen bond	646:658	The mechanism study reveals that the adsorption of Sb initializes from the Fe3O4, propagates along the chitosan with hydrogen bond, and terminates at the inner sphere complex with the EDTA moiety in the adsorbent.					
36503750	1	43	theme	emerging	141:148	arg1	Antimony					116:123	Antimony	116:123	Antimony	116:123	Antimony is more than an emerging pollutant in water but a scare resource.					
36503750	1	43	theme	emerging	141:148	arg1	pollutant					150:158	an emerging pollutant	138:158	an emerging pollutant in water	138:167	Antimony is more than an emerging pollutant in water but a scare resource.					
36503750	3	44	theme	grafted	400:406	arg1	chitosan					408:415	the EDTA grafted chitosan	391:415	the EDTA grafted chitosan	391:415	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	45	theme	mg/g	499:502	arg1	V					511:511	V	511:511	V	511:511	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	45	theme	mg/g	499:502	arg1	Sb					508:509	467.3 mg/g for Sb	493:509	467.3 mg/g for Sb(V)	493:512	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	46	theme	superhigh	429:437	arg1	capacity					450:457	superhigh adsorption capacity	429:457	superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively	429:526	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	47	contain	has	425:427	arg2	capacity					450:457	superhigh adsorption capacity	429:457	superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively	429:526	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	47	contain	has	425:427	arg1	it					422:423	it	422:423	it	422:423	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	48	theme	for	504:506	arg1	V					511:511	V	511:511	V	511:511	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	3	48	theme	for	504:506	arg1	Sb					508:509	467.3 mg/g for Sb	493:509	467.3 mg/g for Sb(V)	493:512	The composite adsorbent was fabricated by encapsulating hollow Fe3O4 nanosphere with the EDTA grafted chitosan, and it has superhigh adsorption capacity of for 657.1 mg/g for Sb(III) and 467.3 mg/g for Sb(V), respectively.					
36503750	2	49	theme	Sb	299:300	arg1	view					279:282	the balanced view	266:282	the balanced view of Sb(III) and Sb(V)	266:303	In this study, we report an adsorbent with the record capacity so far from the balanced view of Sb(III) and Sb(V).					
36109175	0	0	from	Symptoms	69:76	arg1	Mice					81:84	Mice	81:84	Mice	81:84	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	3	1	theme	KM	358:359	arg1	mice					361:364	KM mice	358:364	KM mice	358:364	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	3	2	theme	diarrhea	532:539	arg1	model					541:545	diarrhea model	532:545	diarrhea model	532:545	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	4	3	theme	anti-inflammatory	774:790	arg1	factor					792:797	anti-inflammatory factor	774:797	anti-inflammatory factor	774:797	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	4	theme	XOS	579:581	arg1	doses					570:574	doses	570:574	doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	570:627	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	0	5	theme	Intestinal	90:99	arg1	Improvement					109:119	Intestinal Barrier Improvement	90:119	Intestinal Barrier Improvement	90:119	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	3	6	dep	extracts	465:472	arg1	solutions					474:482	solutions	474:482	then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> )	421:507	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	3	6	dep	extracts	465:472	arg1	0.8 g mL<sup>-1</sup>					485:505	0.8 g mL<sup>-1</sup>	485:505	0.8 g mL<sup>-1</sup>	485:505	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	5	7	theme	gut	900:902	arg1	microbiota					904:913	gut microbiota	900:913	gut microbiota	900:913	XOS also regulates the composition of gut microbiota via increasing the abundance Prevotellaceae, Ruminococcus, and Bifidobacterium.					
36109175	3	8	theme	Folium	426:431	arg1	Sennae					433:438	Folium Sennae	426:438	then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> )	421:507	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	3	8	theme	Folium	426:431	arg1	alexandrina Mill					447:462	Senna alexandrina Mill	441:462	Senna alexandrina Mill	441:462	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	0	9	theme	Administered	7:18	arg1	Xylo-Oligosaccharides					20:40	Orally Administered Xylo-Oligosaccharides	0:40	Orally Administered Xylo-Oligosaccharides (XOS)	0:46	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	0	9	theme	Administered	7:18	arg1	XOS					43:45	XOS	43:45	XOS	43:45	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	2	10	theme	Sennae	316:321	arg1	extracts					323:330	Folium Sennae extracts	309:330	Folium Sennae extracts	309:330	This study aims to investigate how XOS alleviates Folium Sennae extracts induced diarrhea in mice.					
36109175	1	11	theme	bidirectional	186:198	arg1	effect					211:216	a bidirectional regulatory effect	184:216	a bidirectional regulatory effect	184:216	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	3	12	theme	concentration	386:398	arg1	XOS					400:402	different concentration XOS	376:402	different concentration XOS	376:402	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	6	13	theme	supplementation	1032:1046	arg1	XOS					1048:1050	the dietary supplementation XOS	1020:1050	the dietary supplementation XOS	1020:1050	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	6	13	theme	supplementation	1032:1046	arg1	choice					1078:1083	a more effective choice to prevent and alleviate diarrhea	1061:1117	a more effective choice to prevent and alleviate diarrhea	1061:1117	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	2	14	theme	Folium	309:314	arg1	extracts					323:330	Folium Sennae extracts	309:330	Folium Sennae extracts	309:330	This study aims to investigate how XOS alleviates Folium Sennae extracts induced diarrhea in mice.					
36109175	1	15	theme	regulatory	200:209	arg1	effect					211:216	a bidirectional regulatory effect	184:216	a bidirectional regulatory effect	184:216	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	6	16	theme	dietary	1024:1030	arg1	XOS					1048:1050	the dietary supplementation XOS	1020:1050	the dietary supplementation XOS	1020:1050	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	6	16	theme	dietary	1024:1030	arg1	choice					1078:1083	a more effective choice to prevent and alleviate diarrhea	1061:1117	a more effective choice to prevent and alleviate diarrhea	1061:1117	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	0	17	theme	Microbiota	129:138	arg1	Modulation					140:149	Gut Microbiota Modulation	125:149	Gut Microbiota Modulation	125:149	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	3	18	theme	Senna	441:445	arg1	Sennae					433:438	Folium Sennae	426:438	then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> )	421:507	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	3	18	theme	Senna	441:445	arg1	alexandrina Mill					447:462	Senna alexandrina Mill	441:462	Senna alexandrina Mill	441:462	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	0	19	theme	Gut	125:127	arg1	Modulation					140:149	Gut Microbiota Modulation	125:149	Gut Microbiota Modulation	125:149	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	4	20	theme	activity	700:707	arg1	indexes					709:715	the disease activity indexes	688:715	the disease activity indexes	688:715	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	5	21	theme	microbiota	904:913	arg1	composition					885:895	the composition	881:895	the composition of gut microbiota	881:913	XOS also regulates the composition of gut microbiota via increasing the abundance Prevotellaceae, Ruminococcus, and Bifidobacterium.					
36109175	3	22	theme	Sennae	433:438	arg1	extracts					465:472	then Folium Sennae (Senna alexandrina Mill) extracts	421:472	then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> )	421:507	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	0	23	theme	Diarrhea	60:67	arg1	Symptoms					69:76	Diarrhea Symptoms	60:76	Diarrhea Symptoms in Mice	60:84	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	0	24	theme	Barrier	101:107	arg1	Improvement					109:119	Intestinal Barrier Improvement	90:119	Intestinal Barrier Improvement	90:119	Orally Administered Xylo-Oligosaccharides (XOS) Ameliorates Diarrhea Symptoms in Mice via Intestinal Barrier Improvement and Gut Microbiota Modulation.					
36109175	1	25	contain	has	180:182	arg1	XOS					175:177	XOS	175:177	XOS	175:177	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	1	25	contain	has	180:182	arg2	effect					211:216	a bidirectional regulatory effect	184:216	a bidirectional regulatory effect	184:216	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	1	25	contain	has	180:182	arg1	Xylo-oligosaccharides					152:172	Xylo-oligosaccharides	152:172	Xylo-oligosaccharides (XOS)	152:178	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	4	26	theme	0.25 mg g<sup>-1</sup>	586:607	arg1	day<sup>-1</sup>					612:627	0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	586:627	0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	586:627	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	27	theme	intestinal	820:829	arg1	permeability					831:842	the intestinal permeability	816:842	the intestinal permeability in colon tissues	816:859	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	28	theme	pro-inflammatory	734:749	arg1	factors					751:757	pro-inflammatory factors	734:757	pro-inflammatory factors	734:757	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	29	from	day<sup>-1</sup>	612:627	arg1	doses					570:574	doses	570:574	doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	570:627	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	5	30	theme	abundance	934:942	arg1	Prevotellaceae					944:957	the abundance Prevotellaceae	930:957	the abundance Prevotellaceae	930:957	XOS also regulates the composition of gut microbiota via increasing the abundance Prevotellaceae, Ruminococcus, and Bifidobacterium.					
36109175	4	31	theme	colon	847:851	arg1	tissues					853:859	colon tissues	847:859	colon tissues	847:859	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	32	theme	disease	692:698	arg1	indexes					709:715	the disease activity indexes	688:715	the disease activity indexes	688:715	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	4	33	theme	diarrhea	656:663	arg1	symptoms					665:672	diarrhea symptoms	656:672	diarrhea symptoms	656:672	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	6	34	theme	effective	1068:1076	arg1	XOS					1048:1050	the dietary supplementation XOS	1020:1050	the dietary supplementation XOS	1020:1050	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	6	34	theme	effective	1068:1076	arg1	choice					1078:1083	a more effective choice to prevent and alleviate diarrhea	1061:1117	a more effective choice to prevent and alleviate diarrhea	1061:1117	The results suggest that the dietary supplementation XOS could be a more effective choice to prevent and alleviate diarrhea.					
36109175	1	35	theme	gut	243:245	arg1	microbiota					247:256	gut microbiota	243:256	gut microbiota	243:256	Xylo-oligosaccharides (XOS) has a bidirectional regulatory effect, and can be fermented by gut microbiota.					
36109175	4	36	from	permeability	831:842	arg1	tissues					853:859	colon tissues	847:859	colon tissues	847:859	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36109175	3	37	theme	different	376:384	arg1	XOS					400:402	different concentration XOS	376:402	different concentration XOS	376:402	KM mice are given different concentration XOS for 3 weeks, and then Folium Sennae (Senna alexandrina Mill) extracts solutions (0.8 g mL<sup>-1</sup> ) are given to establish diarrhea model.					
36109175	4	38	theme	BW	609:610	arg1	day<sup>-1</sup>					612:627	0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	586:627	0.25 mg g<sup>-1</sup> BW day<sup>-1</sup>	586:627	The results show that doses of XOS at 0.25 mg g<sup>-1</sup> BW day<sup>-1</sup> and higher could alleviate diarrhea symptoms by decreasing the disease activity indexes, down-regulating pro-inflammatory factors, up-regulating anti-inflammatory factor, and suppressing the intestinal permeability in colon tissues.					
36469033	6	0	theme	elevated	1020:1027	arg1	temperature					1029:1039	elevated temperature	1020:1039	elevated temperature	1020:1039	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	4	1	theme	nanocellulose-based	655:673	arg1	scaffolds					685:693	nanocellulose-based 3D porous scaffolds	655:693	nanocellulose-based 3D porous scaffolds	655:693	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	9	2	theme	specific	1657:1664	arg1	activities					1666:1675	Their specific activities	1651:1675	Their specific activities	1651:1675	Their specific activities were 0.50 U/mg (Zbasic2-CGT) and 0.19 U/mg (Zbasic2-SuSy), corresponding to an efficacy of 37 and 18%, respectively, compared to the soluble enzymes.					
36469033	10	3	theme	%	1986:1986	arg1	conversion					1988:1997	∼95% conversion	1983:1997	1.0 mM; ∼95% conversion	1975:1997	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	2	4	theme	3D	296:297	arg1	scaffolds					299:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	2	4	theme	3D	296:297	arg1	carriers					323:330	compatible carriers	312:330	compatible carriers	312:330	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	4	5	theme	responsible	743:753	arg1	glycosyltransferases					721:740	glycosyltransferases	721:740	glycosyltransferases	721:740	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	2	6	theme	compatible	312:321	arg1	scaffolds					299:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	2	6	theme	compatible	312:321	arg1	carriers					323:330	compatible carriers	312:330	compatible carriers	312:330	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	1	7	theme	complex	207:213	arg1	molecules					215:223	industrially relevant complex molecules	185:223	industrially relevant complex molecules	185:223	Biocatalysis is increasingly becoming an alternative method for the synthesis of industrially relevant complex molecules.					
36469033	10	8	from	phloretin	1964:1972	arg1	nothofagin					1948:1957	the natural C-glycoside nothofagin	1924:1957	the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion)	1924:1998	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	11	9	theme	reactions	2077:2085	arg1	maximum					2052:2058	a maximum	2050:2058	a maximum of 5 consecutive reactions	2050:2085	All enzyme bound scaffolds showed reusability of a maximum of 5 consecutive reactions.					
36469033	7	10	theme	enzyme	1516:1521	arg1	adsorption					1523:1532	charge-based enzyme adsorption	1503:1532	charge-based enzyme adsorption	1503:1532	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	12	11	theme	cross-linked	2134:2145	arg1	scaffolds					2161:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	2	12	theme	defined	338:344	arg1	properties					346:355	defined properties	338:355	defined properties	338:355	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	4	13	from	immobilization	703:716	arg1	biosynthesis					784:795	natural biosynthesis	776:795	natural biosynthesis	776:795	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	5	14	theme	citric	918:923	arg1	acid					925:928	citric acid	918:928	citric acid	918:928	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	4	15	theme	glycosyltransferases	721:740	arg1	immobilization					703:716	the immobilization	699:716	the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis	699:795	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	2	16	theme	enzyme	256:261	arg1	scaffolds					299:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	2	16	theme	enzyme	256:261	arg1	carriers					323:330	compatible carriers	312:330	compatible carriers	312:330	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	10	17	dep	mM	1979:1980	arg1	conversion					1988:1997	∼95% conversion	1983:1997	1.0 mM; ∼95% conversion	1975:1997	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	1	18	theme	alternative	145:155	arg1	method					157:162	an alternative method	142:162	an alternative method for the synthesis of industrially relevant complex molecules	142:223	Biocatalysis is increasingly becoming an alternative method for the synthesis of industrially relevant complex molecules.					
36469033	12	19	theme	printed	2122:2128	arg1	scaffolds					2161:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	8	20	theme	carrier	1595:1601	arg1	protein/g					1578:1586	protein/g	1578:1586	protein/g of dry carrier (∼20% yield)	1578:1614	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	7	21	theme	binding	1467:1473	arg1	Zbasic2					1483:1489	Zbasic2	1483:1489	Zbasic2	1483:1489	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	7	21	theme	binding	1467:1473	arg1	module					1475:1480	a cationic binding module	1456:1480	a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption	1456:1532	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	4	22	theme	natural	776:782	arg1	biosynthesis					784:795	natural biosynthesis	776:795	natural biosynthesis	776:795	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	7	23	theme	nucleotide-dependent	1329:1348	arg1	glycosyltransferases					1350:1369	two sugar nucleotide-dependent glycosyltransferases	1319:1369	two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy)	1319:1438	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	7	23	theme	nucleotide-dependent	1329:1348	arg1	each					1441:1444	each	1441:1444	each	1441:1444	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	2	24	theme	polysaccharide-based	275:294	arg1	scaffolds					299:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	2	24	theme	polysaccharide-based	275:294	arg1	carriers					323:330	compatible carriers	312:330	compatible carriers	312:330	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	9	25	theme	soluble	1810:1816	arg1	enzymes					1818:1824	the soluble enzymes	1806:1824	the soluble enzymes	1806:1824	Their specific activities were 0.50 U/mg (Zbasic2-CGT) and 0.19 U/mg (Zbasic2-SuSy), corresponding to an efficacy of 37 and 18%, respectively, compared to the soluble enzymes.					
36469033	8	26	theme	∼20	1604:1606	arg1	%					1607:1607	%	1607:1607	%	1607:1607	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	0	27	theme	Glycosyltransferases	82:101	arg1	Immobilization					64:77	Immobilization	64:77	Immobilization of Glycosyltransferases	64:101	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.					
36469033	11	28	theme	enzyme	2005:2010	arg1	scaffolds					2018:2026	All enzyme bound scaffolds	2001:2026	All enzyme bound scaffolds	2001:2026	All enzyme bound scaffolds showed reusability of a maximum of 5 consecutive reactions.					
36469033	3	29	theme	multiple	405:412	arg1	enzymes					414:420	either single or multiple enzymes	388:420	either single or multiple enzymes	388:420	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	11	30	theme	maximum	2052:2058	arg1	reusability					2035:2045	reusability	2035:2045	reusability of a maximum of 5 consecutive reactions	2035:2085	All enzyme bound scaffolds showed reusability of a maximum of 5 consecutive reactions.					
36469033	6	31	theme	negative	1106:1113	arg1	charges					1115:1121	tunable negative charges	1098:1121	tunable negative charges (2.2-5.0 mmol/g)	1098:1138	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	31	theme	negative	1106:1113	arg1	mmol/g					1132:1137	2.2-5.0 mmol/g	1124:1137	2.2-5.0 mmol/g	1124:1137	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	3	32	theme	single	395:400	arg1	enzymes					414:420	either single or multiple enzymes	388:420	either single or multiple enzymes	388:420	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	6	33	from	charges	1115:1121	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	3	34	theme	porous	504:509	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	34	theme	porous	504:509	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	7	35	theme	cationic	1458:1465	arg1	Zbasic2					1483:1489	Zbasic2	1483:1489	Zbasic2	1483:1489	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	7	35	theme	cationic	1458:1465	arg1	module					1475:1480	a cationic binding module	1456:1480	a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption	1456:1532	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	3	36	theme	3D	427:428	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	36	theme	3D	427:428	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	36	theme	3D	427:428	arg1	morphology					525:534	morphology	525:534	morphology	525:534	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	37	theme	well-organized	474:487	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	37	theme	well-organized	474:487	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	0	38	theme	3D	0:1	arg1	Scaffolds					38:46	3D Printed Porous Nanocellulose-Based Scaffolds	0:46	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.	0:102	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.					
36469033	10	39	from	active	1887:1892	arg1	reaction					1907:1914	a cascade reaction	1897:1914	a cascade reaction	1897:1914	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	8	40	theme	scaffold	1636:1643	arg1	independent					1617:1627	independent	1617:1627	independent	1617:1627	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	12	41	theme	promising	2248:2256	arg1	applications					2258:2269	promising applications	2248:2269	promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis	2248:2345	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	0	42	theme	Porous	11:16	arg1	Scaffolds					38:46	3D Printed Porous Nanocellulose-Based Scaffolds	0:46	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.	0:102	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.					
36469033	7	43	theme	charged	1274:1280	arg1	scaffolds					1282:1290	The negatively charged scaffolds	1259:1290	The negatively charged scaffolds	1259:1290	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	6	44	theme	3D	950:951	arg1	printing					953:960	Direct-ink-writing 3D printing	931:960	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature	931:1039	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	3	45	theme	polysaccharide	438:451	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	45	theme	polysaccharide	438:451	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	45	theme	polysaccharide	438:451	arg1	morphology					525:534	morphology	525:534	morphology	525:534	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	10	46	theme	cascade	1899:1905	arg1	reaction					1907:1914	a cascade reaction	1897:1914	a cascade reaction	1897:1914	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	6	47	from	dimensional	1204:1214	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	48	theme	mechanical	1220:1229	arg1	stability					1231:1239	mechanical stability	1220:1239	mechanical stability	1220:1239	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	11	49	theme	bound	2012:2016	arg1	scaffolds					2018:2026	All enzyme bound scaffolds	2001:2026	All enzyme bound scaffolds	2001:2026	All enzyme bound scaffolds showed reusability of a maximum of 5 consecutive reactions.					
36469033	10	50	theme	C-glycoside	1936:1946	arg1	nothofagin					1948:1957	the natural C-glycoside nothofagin	1924:1957	the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion)	1924:1998	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	12	51	theme	solid	2196:2200	arg1	carriers					2202:2209	solid carriers	2196:2209	solid carriers for enzyme (co)-immobilization	2196:2240	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	3	52	theme	important	603:611	arg1	enzymes					613:619	industrially important enzymes	590:619	industrially important enzymes	590:619	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	4	53	theme	3D	675:676	arg1	scaffolds					685:693	nanocellulose-based 3D porous scaffolds	655:693	nanocellulose-based 3D porous scaffolds	655:693	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	6	54	from	capacity	1178:1185	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	4	55	theme	scaffolds	685:693	arg1	use					648:650	the use	644:650	the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis	644:795	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	12	56	theme	biocatalysis	2334:2345	arg1	fields					2324:2329	other fields	2318:2329	other fields of biocatalysis	2318:2345	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	12	56	theme	biocatalysis	2334:2345	arg1	synthesis					2304:2312	glycosyltransferase-catalyzed synthesis	2274:2312	glycosyltransferase-catalyzed synthesis	2274:2312	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	3	57	theme	enzymes	613:619	arg1	performance					575:585	the performance	571:585	the performance of industrially important enzymes	571:619	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	6	58	theme	dehydrothermal	992:1005	arg1	treatment					1007:1015	freeze-drying and dehydrothermal treatment	974:1015	freeze-drying and dehydrothermal treatment	974:1015	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	10	59	theme	∼95	1983:1985	arg1	%					1986:1986	%	1986:1986	%	1986:1986	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	1	60	theme	relevant	198:205	arg1	molecules					215:223	industrially relevant complex molecules	185:223	industrially relevant complex molecules	185:223	Biocatalysis is increasingly becoming an alternative method for the synthesis of industrially relevant complex molecules.					
36469033	6	61	theme	freeze-drying	974:986	arg1	treatment					1007:1015	freeze-drying and dehydrothermal treatment	974:1015	freeze-drying and dehydrothermal treatment	974:1015	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	62	from	sizes	1146:1150	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	11	63	theme	consecutive	2065:2075	arg1	reactions					2077:2085	5 consecutive reactions	2063:2085	5 consecutive reactions	2063:2085	All enzyme bound scaffolds showed reusability of a maximum of 5 consecutive reactions.					
36469033	12	64	from	applications	2258:2269	arg1	fields					2324:2329	other fields	2318:2329	other fields of biocatalysis	2318:2345	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	12	64	from	applications	2258:2269	arg1	synthesis					2304:2312	glycosyltransferase-catalyzed synthesis	2274:2312	glycosyltransferase-catalyzed synthesis	2274:2312	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	1	65	theme	molecules	215:223	arg1	synthesis					172:180	the synthesis	168:180	the synthesis of industrially relevant complex molecules	168:223	Biocatalysis is increasingly becoming an alternative method for the synthesis of industrially relevant complex molecules.					
36469033	6	66	theme	tunable	1098:1104	arg1	charges					1115:1121	tunable negative charges	1098:1121	tunable negative charges (2.2-5.0 mmol/g)	1098:1138	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	66	theme	tunable	1098:1104	arg1	mmol/g					1132:1137	2.2-5.0 mmol/g	1124:1137	2.2-5.0 mmol/g	1124:1137	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	67	theme	wet	1248:1250	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	2	68	theme	immobilized	263:273	arg1	scaffolds					299:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	enzyme immobilized polysaccharide-based 3D scaffolds	256:307	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	2	68	theme	immobilized	263:273	arg1	carriers					323:330	compatible carriers	312:330	compatible carriers	312:330	This can be realized by using enzyme immobilized polysaccharide-based 3D scaffolds as compatible carriers, with defined properties.					
36469033	6	69	theme	cross-linked	1064:1075	arg1	scaffolds					1077:1085	chemically cross-linked scaffolds	1053:1085	chemically cross-linked scaffolds	1053:1085	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	9	70	theme	%	1777:1777	arg1	efficacy					1756:1763	an efficacy	1753:1763	an efficacy of 37 and 18%	1753:1777	Their specific activities were 0.50 U/mg (Zbasic2-CGT) and 0.19 U/mg (Zbasic2-SuSy), corresponding to an efficacy of 37 and 18%, respectively, compared to the soluble enzymes.					
36469033	8	71	theme	protein/g	1578:1586	arg1	mg					1572:1573	∼30 mg	1568:1573	∼30 mg of protein/g of dry carrier (∼20% yield)	1568:1614	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	7	72	theme	charge-based	1503:1514	arg1	adsorption					1523:1532	charge-based enzyme adsorption	1503:1532	charge-based enzyme adsorption	1503:1532	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	12	73	theme	NFC/CMC-based	2147:2159	arg1	scaffolds					2161:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	8	74	theme	dry	1591:1593	arg1	yield					1609:1613	∼20% yield	1604:1613	∼20% yield	1604:1613	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	8	74	theme	dry	1591:1593	arg1	carrier					1595:1601	dry carrier	1591:1601	dry carrier (∼20% yield)	1591:1614	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	3	75	from	immobilization	370:383	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	75	from	immobilization	370:383	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	75	from	immobilization	370:383	arg1	morphology					525:534	morphology	525:534	morphology	525:534	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	6	76	theme	pore	1141:1144	arg1	sizes					1146:1150	pore sizes	1141:1150	pore sizes (10-800 μm)	1141:1162	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	76	theme	pore	1141:1144	arg1	μm					1160:1161	10-800 μm	1153:1161	10-800 μm	1153:1161	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	12	77	theme	3D	2119:2120	arg1	scaffolds					2161:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	5	78	theme	nanofibrillated	850:864	arg1	cellulose					866:874	nanofibrillated cellulose	850:874	nanofibrillated cellulose (NFC)	850:880	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	78	theme	nanofibrillated	850:864	arg1	NFC					877:879	NFC	877:879	NFC	877:879	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	6	79	link	cross-linked	1064:1075	arg1	scaffolds					1077:1085	chemically cross-linked scaffolds	1053:1085	chemically cross-linked scaffolds	1053:1085	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	8	80	theme	%	1607:1607	arg1	yield					1609:1613	∼20% yield	1604:1613	∼20% yield	1604:1613	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	8	80	theme	%	1607:1607	arg1	carrier					1595:1601	dry carrier	1591:1601	dry carrier (∼20% yield)	1591:1614	Both enzymes were immobilized at ∼30 mg of protein/g of dry carrier (∼20% yield), independent of the scaffold used.					
36469033	12	81	theme	other	2318:2322	arg1	fields					2324:2329	other fields	2318:2329	other fields of biocatalysis	2318:2345	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	3	82	theme	enzymes	414:420	arg1	approach					552:559	a versatile approach	540:559	a versatile approach to access the performance of industrially important enzymes	540:619	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	82	theme	enzymes	414:420	arg1	immobilization					370:383	immobilization	370:383	immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology,	370:535	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	5	83	contain	containing	839:848	arg2	NFC					877:879	NFC	877:879	NFC	877:879	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	83	contain	containing	839:848	arg2	cellulose					866:874	nanofibrillated cellulose	850:874	nanofibrillated cellulose (NFC)	850:880	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	83	contain	containing	839:848	arg2	cellulose					897:905	carboxymethyl cellulose	883:905	carboxymethyl cellulose (CMC)	883:911	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	83	contain	containing	839:848	arg1	ink					835:837	an ink	832:837	an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid	832:928	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	83	contain	containing	839:848	arg2	CMC					908:910	CMC	908:910	CMC	908:910	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	83	contain	containing	839:848	arg2	acid					925:928	citric acid	918:928	citric acid	918:928	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	6	84	theme	uptake	1171:1176	arg1	capacity					1178:1185	fluid uptake capacity	1165:1185	fluid uptake capacity	1165:1185	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	12	85	theme	glycosyltransferase-catalyzed	2274:2302	arg1	synthesis					2304:2312	glycosyltransferase-catalyzed synthesis	2274:2312	glycosyltransferase-catalyzed synthesis	2274:2312	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	0	86	theme	Printed	3:9	arg1	Scaffolds					38:46	3D Printed Porous Nanocellulose-Based Scaffolds	0:46	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.	0:102	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.					
36469033	7	87	dep	glycosyltransferases	1350:1369	arg1	C-glycosyltransferase					1372:1392	C-glycosyltransferase	1372:1392	C-glycosyltransferase	1372:1392	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	7	87	dep	glycosyltransferases	1350:1369	arg1	Zbasic2-SuSy					1426:1437	Zbasic2-SuSy	1426:1437	Zbasic2-SuSy	1426:1437	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	7	87	dep	glycosyltransferases	1350:1369	arg1	Zbasic2-CGT					1395:1405	Zbasic2-CGT	1395:1405	Zbasic2-CGT	1395:1405	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	3	88	theme	printed	430:436	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	88	theme	printed	430:436	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	88	theme	printed	430:436	arg1	morphology					525:534	morphology	525:534	morphology	525:534	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	89	theme	interconnected	489:502	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	89	theme	interconnected	489:502	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	0	90	theme	Nanocellulose-Based	18:36	arg1	Scaffolds					38:46	3D Printed Porous Nanocellulose-Based Scaffolds	0:46	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.	0:102	3D Printed Porous Nanocellulose-Based Scaffolds As Carriers for Immobilization of Glycosyltransferases.					
36469033	7	91	dep	C-glycosyltransferase	1372:1392	arg1	synthase					1416:1423	sucrose synthase	1408:1423	sucrose synthase	1408:1423	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	12	92	link	cross-linked	2134:2145	arg1	scaffolds					2161:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	the 3D printed and cross-linked NFC/CMC-based scaffolds	2115:2169	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	3	93	theme	exhibiting	463:472	arg1	scaffold					453:460	a 3D printed polysaccharide scaffold	425:460	a 3D printed polysaccharide scaffold	425:460	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	93	theme	exhibiting	463:472	arg1	structure					511:519	exhibiting well-organized interconnected porous structure	463:519	exhibiting well-organized interconnected porous structure	463:519	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	10	94	dep	phloretin	1964:1972	arg1	mM					1979:1980	1.0 mM	1975:1980	1.0 mM; ∼95% conversion	1975:1997	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	12	95	theme	enzyme	2215:2220	arg1	-immobilization					2226:2240	enzyme (co)-immobilization	2215:2240	enzyme (co)-immobilization	2215:2240	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	5	96	theme	carboxymethyl	883:895	arg1	CMC					908:910	CMC	908:910	CMC	908:910	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	5	96	theme	carboxymethyl	883:895	arg1	cellulose					897:905	carboxymethyl cellulose	883:905	carboxymethyl cellulose (CMC)	883:911	The scaffolds were produced using an ink containing nanofibrillated cellulose (NFC), carboxymethyl cellulose (CMC), and citric acid.					
36469033	6	97	theme	Direct-ink-writing	931:948	arg1	printing					953:960	Direct-ink-writing 3D printing	931:960	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature	931:1039	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	7	98	theme	sucrose	1408:1414	arg1	synthase					1416:1423	sucrose synthase	1408:1423	sucrose synthase	1408:1423	The negatively charged scaffolds were applied to immobilize two sugar nucleotide-dependent glycosyltransferases (C-glycosyltransferase, Zbasic2-CGT; sucrose synthase, Zbasic2-SuSy), each harboring a cationic binding module (Zbasic2) to promote charge-based enzyme adsorption.					
36469033	12	99	theme	co	2223:2224	arg1	-immobilization					2226:2240	enzyme (co)-immobilization	2215:2240	enzyme (co)-immobilization	2215:2240	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36469033	6	100	from	stability	1231:1239	arg1	state					1252:1256	the wet state	1244:1256	the wet state	1244:1256	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	4	101	theme	porous	678:683	arg1	scaffolds					685:693	nanocellulose-based 3D porous scaffolds	655:693	nanocellulose-based 3D porous scaffolds	655:693	Here, we demonstrated the use of nanocellulose-based 3D porous scaffolds for the immobilization of glycosyltransferases, responsible for glycosylation in natural biosynthesis.					
36469033	10	102	theme	natural	1928:1934	arg1	nothofagin					1948:1957	the natural C-glycoside nothofagin	1924:1957	the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion)	1924:1998	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	3	103	theme	versatile	542:550	arg1	approach					552:559	a versatile approach	540:559	a versatile approach to access the performance of industrially important enzymes	540:619	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	3	103	theme	versatile	542:550	arg1	immobilization					370:383	immobilization	370:383	immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology,	370:535	Especially, immobilization of either single or multiple enzymes on a 3D printed polysaccharide scaffold, exhibiting well-organized interconnected porous structure and morphology, is a versatile approach to access the performance of industrially important enzymes.					
36469033	10	104	from	reaction	1907:1914	arg1	active					1887:1892	active	1887:1892	active	1887:1892	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	10	104	from	reaction	1907:1914	arg1	glycosyltransferases					1831:1850	The glycosyltransferases	1827:1850	The glycosyltransferases	1827:1850	The glycosyltransferases were coimmobilized and shown to be active in a cascade reaction to give the natural C-glycoside nothofagin from phloretin (1.0 mM; ∼95% conversion).					
36469033	6	105	theme	exceptional	1192:1202	arg1	dimensional					1204:1214	exceptional dimensional	1192:1214	exceptional dimensional	1192:1214	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	6	106	theme	fluid	1165:1169	arg1	capacity					1178:1185	fluid uptake capacity	1165:1185	fluid uptake capacity	1165:1185	Direct-ink-writing 3D printing followed by freeze-drying and dehydrothermal treatment at elevated temperature resulted in chemically cross-linked scaffolds, featuring tunable negative charges (2.2-5.0 mmol/g), pore sizes (10-800 μm), fluid uptake capacity, and exceptional dimensional and mechanical stability in the wet state.					
36469033	12	107	theme	carriers	2202:2209	arg1	class					2187:2191	a class	2185:2191	a class of solid carriers for enzyme (co)-immobilization	2185:2240	These results suggest that the 3D printed and cross-linked NFC/CMC-based scaffolds could present a class of solid carriers for enzyme (co)-immobilization, with promising applications in glycosyltransferase-catalyzed synthesis and other fields of biocatalysis.					
36167210	0	0	theme	hydrazine	96:104	arg1	monitoring					82:91	the monitoring	78:91	the monitoring of hydrazine as a pollutant in water and wastewater samples	78:151	Electrochemical sensor amplified with cellulose nanofibers/Fe3O4 composite to the monitoring of hydrazine as a pollutant in water and wastewater samples.					
36167210	4	1	theme	current	683:689	arg1	oxidation					673:681	the oxidation current	669:689	the oxidation current of hydrazine	669:702	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	4	2	theme	unmodified	837:846	arg1	GCE					848:850	unmodified GCE	837:850	unmodified GCE	837:850	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	1	3	theme	swift	162:166	arg1	instrument					193:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	5	4	from	detection	941:949	arg1	water					967:971	water	967:971	water	967:971	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	5	4	from	detection	941:949	arg1	samples					988:994	wastewater samples	977:994	wastewater samples	977:994	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	2	5	theme	0.5 nM	513:518	arg1	limit					504:508	a superior detection limit	483:508	a superior detection limit of 0.5 nM	483:518	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	3	6	theme	diffusion	538:546	arg1	process					556:562	a diffusion control process	536:562	a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE	536:628	Results showed a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE.					
36167210	1	7	theme	various	265:271	arg1	water					273:277	various water and wastewater samples	265:300	water	273:277	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	4	8	theme	CNF-Fe3O4/NC/GCE	809:824	arg1	surface					798:804	the surface	794:804	the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE	794:850	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	5	9	theme	hydrazine	954:962	arg1	detection					941:949	the detection	937:949	the detection of hydrazine in water and wastewater samples	937:994	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	3	10	from	surface	602:608	arg1	oxidation					572:580	the oxidation	568:580	the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE	568:628	Results showed a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE.					
36167210	0	11	theme	Electrochemical	0:14	arg1	sensor					16:21	Electrochemical sensor	0:21	Electrochemical sensor	0:21	Electrochemical sensor amplified with cellulose nanofibers/Fe3O4 composite to the monitoring of hydrazine as a pollutant in water and wastewater samples.					
36167210	1	12	theme	sensitive	172:180	arg1	instrument					193:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	2	13	theme	carbon	314:319	arg1	GCE					332:334	GCE	332:334	GCE	332:334	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	13	theme	carbon	314:319	arg1	electrode					321:329	The glassy carbon electrode	303:329	The glassy carbon electrode (GCE)	303:335	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	1	14	theme	analytical	182:191	arg1	instrument					193:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument	154:202	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	2	15	theme	concentration	441:453	arg1	range					455:459	the concentration range	437:459	the concentration range of 0.001 - 140 M	437:476	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	16	theme	glassy	307:312	arg1	GCE					332:334	GCE	332:334	GCE	332:334	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	16	theme	glassy	307:312	arg1	electrode					321:329	The glassy carbon electrode	303:329	The glassy carbon electrode (GCE)	303:335	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	17	theme	nanofibers/Fe3O4	367:382	arg1	CNF-Fe3O4/NC					395:406	CNF-Fe3O4/NC	395:406	CNF-Fe3O4/NC	395:406	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	17	theme	nanofibers/Fe3O4	367:382	arg1	composite					384:392	cellulose nanofibers/Fe3O4 composite	357:392	cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM	357:518	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	4	18	dep	CNF-Fe3O4/NC/GCE	809:824	arg1	compare					826:832	compare	826:832	compare to unmodified GCE	826:850	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	3	19	theme	control	548:554	arg1	process					556:562	a diffusion control process	536:562	a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE	536:628	Results showed a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE.					
36167210	1	20	theme	wastewater	283:292	arg1	samples					294:300	various water and wastewater samples	265:300	samples	294:300	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	5	21	theme	standard	855:862	arg1	method					873:878	A standard addition method	853:878	A standard addition method	853:878	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	2	22	theme	140 M	472:476	arg1	range					455:459	the concentration range	437:459	the concentration range of 0.001 - 140 M	437:476	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	3	23	theme	hydrazine	585:593	arg1	oxidation					572:580	the oxidation	568:580	the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE	568:628	Results showed a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE.					
36167210	4	24	theme	optimum	641:647	arg1	pH=8.0					660:665	pH=8.0	660:665	pH=8.0	660:665	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	4	24	theme	optimum	641:647	arg1	condition					649:657	the optimum condition	637:657	the optimum condition (pH=8.0)	637:666	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	1	25	from	hydrazine	252:260	arg1	water					273:277	various water and wastewater samples	265:300	water	273:277	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	1	25	from	hydrazine	252:260	arg1	samples					294:300	various water and wastewater samples	265:300	samples	294:300	A quite swift and sensitive analytical instrument was designed in this work to detect and monitor hydrazine in various water and wastewater samples.					
36167210	5	26	theme	%	1037:1037	arg1	range					1012:1016	a recovery range	1001:1016	a recovery range of 97.6 % to 104.9 %	1001:1037	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	4	27	from	surface	798:804	arg1	60 mV					785:789	about 60 mV	779:789	about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE	779:850	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	2	28	theme	0.001	464:468	arg1	range					455:459	the concentration range	437:459	the concentration range of 0.001 - 140 M	437:476	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	4	29	theme	hydrazine	694:702	arg1	oxidation					673:681	the oxidation current	669:689	the oxidation current of hydrazine	669:702	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	0	30	theme	wastewater	134:143	arg1	samples					145:151	wastewater samples	134:151	wastewater samples	134:151	Electrochemical sensor amplified with cellulose nanofibers/Fe3O4 composite to the monitoring of hydrazine as a pollutant in water and wastewater samples.					
36167210	5	31	theme	recovery	1003:1010	arg1	range					1012:1016	a recovery range	1001:1016	a recovery range of 97.6 % to 104.9 %	1001:1037	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	0	32	from	pollutant	111:119	arg1	water					124:128	water	124:128	water	124:128	Electrochemical sensor amplified with cellulose nanofibers/Fe3O4 composite to the monitoring of hydrazine as a pollutant in water and wastewater samples.					
36167210	0	32	from	pollutant	111:119	arg1	samples					145:151	wastewater samples	134:151	wastewater samples	134:151	Electrochemical sensor amplified with cellulose nanofibers/Fe3O4 composite to the monitoring of hydrazine as a pollutant in water and wastewater samples.					
36167210	5	33	dep	%	1037:1037	arg1	to					1028:1029	to	1028:1029	to	1028:1029	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	4	34	theme	oxidation	744:752	arg1	potential					754:762	the oxidation potential	740:762	the oxidation potential	740:762	Under the optimum condition (pH=8.0), the oxidation current of hydrazine was improved by about 2.3 times and the oxidation potential was reduced by about 60 mV at the surface of CNF-Fe3O4/NC/GCE compare to unmodified GCE.					
36167210	3	35	theme	CNF-Fe3O4/NC/GCE	613:628	arg1	surface					602:608	the surface	598:608	the surface of CNF-Fe3O4/NC/GCE	598:628	Results showed a diffusion control process for the oxidation of hydrazine at the surface of CNF-Fe3O4/NC/GCE.					
36167210	2	36	theme	detection	494:502	arg1	limit					504:508	a superior detection limit	483:508	a superior detection limit of 0.5 nM	483:518	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	5	37	theme	%	1026:1026	arg1	%					1037:1037	97.6 % to 104.9 %	1021:1037	97.6 % to 104.9 %	1021:1037	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	5	38	theme	wastewater	977:986	arg1	samples					988:994	wastewater samples	977:994	wastewater samples	977:994	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36167210	2	39	theme	cellulose	357:365	arg1	CNF-Fe3O4/NC					395:406	CNF-Fe3O4/NC	395:406	CNF-Fe3O4/NC	395:406	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	39	theme	cellulose	357:365	arg1	composite					384:392	cellulose nanofibers/Fe3O4 composite	357:392	cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM	357:518	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	40	theme	superior	485:492	arg1	limit					504:508	a superior detection limit	483:508	a superior detection limit of 0.5 nM	483:518	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	2	41	from	hydrazine	424:432	arg1	range					455:459	the concentration range	437:459	the concentration range of 0.001 - 140 M	437:476	The glassy carbon electrode (GCE) was amplified using cellulose nanofibers/Fe3O4 composite (CNF-Fe3O4/NC) for monitoring hydrazine in the concentration range of 0.001 - 140 M with a superior detection limit of 0.5 nM.					
36167210	5	42	theme	addition	864:871	arg1	method					873:878	A standard addition method	853:878	A standard addition method	853:878	A standard addition method was employed to assess CNF-Fe3O4/NC/GCE's capability for the detection of hydrazine in water and wastewater samples, and a recovery range of 97.6 % to 104.9 % was noted.					
36208076	3	0	theme	mechanical	619:628	arg1	properties					643:652	mechanical and photonic properties	619:652	mechanical and photonic properties that are usually mutually exclusive in synthetic materials	619:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	4	1	theme	biomimetic	720:729	arg1	composites					731:740	These biomimetic composites	714:740	These biomimetic composites	714:740	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	6	2	theme	hydroplastic	1399:1410	arg1	properties					1412:1421	unique hydroplastic properties	1392:1421	unique hydroplastic properties	1392:1421	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	5	3	theme	ultrahigh	979:987	arg1	stiffness					989:997	ultrahigh stiffness	979:997	ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	979:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	6	4	theme	switchable	1302:1311	arg1	photonics					1313:1321	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	photonics	1313:1321	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	3	5	theme	synthetic	693:701	arg1	materials					703:711	synthetic materials	693:711	synthetic materials	693:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	5	6	theme	hydrated	1063:1070	arg1	exoskeleton					1077:1087	hydrated crab exoskeleton	1063:1087	hydrated crab exoskeleton	1063:1087	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	3	7	with	materials	574:582	arg1	combination					604:614	an exceptional combination	589:614	an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials	589:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	7	8	theme	practical	1524:1532	arg1	form					1539:1542	practical bulk form	1524:1542	practical bulk form	1524:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	4	9	theme	materials	842:850	arg1	benchmark					814:822	the benchmark	810:822	the benchmark of natural chiral materials	810:850	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	5	10	theme	exceptional	1157:1167	arg1	strength					1169:1176	exceptional strength	1157:1176	exceptional strength	1157:1176	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	2	11	theme	materials	284:292	arg1	production					233:242	large-scale production	221:242	large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics	221:331	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	5	12	theme	state-a	1037:1043	arg1	value					1045:1049	their fully water-swollen state-a value	1011:1049	their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	1011:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	7	13	theme	materials	1511:1519	arg1	synthesis					1465:1473	a scalable synthesis	1454:1473	a scalable synthesis of resilient biophotonic structural materials in practical bulk form	1454:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	6	14	theme	mineralized	1358:1368	arg1	materials					1370:1378	most artificial mineralized materials	1342:1378	most artificial mineralized materials	1342:1378	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	15	from	materials	1370:1378	arg1	color					1276:1280	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	color	1276:1280	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	15	from	materials	1370:1378	arg1	absent					1332:1337	absent	1332:1337	absent	1332:1337	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	4	16	dep	exhibit	742:748	arg1	which exceeds					796:808	which exceeds	796:808	which exceeds	796:808	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	5	17	from	stiffness	989:997	arg1	value					1045:1049	their fully water-swollen state-a value	1011:1049	their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	1011:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	5	17	from	stiffness	989:997	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	6	18	theme	most	1342:1345	arg1	materials					1370:1378	most artificial mineralized materials	1342:1378	most artificial mineralized materials	1342:1378	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	3	19	from	exclusive	680:688	arg1	materials					703:711	synthetic materials	693:711	synthetic materials	693:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	1	20	theme	desired	187:193	arg1	functionalities					195:209	desired functionalities	187:209	desired functionalities	187:209	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	3	21	theme	artificial	399:408	arg1	strategy					418:425	an efficient and scalable artificial molting strategy	373:425	an efficient and scalable artificial molting strategy	373:425	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	4	22	theme	natural	827:833	arg1	materials					842:850	natural chiral materials	827:850	natural chiral materials	827:850	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	5	23	theme	cartilage	1090:1098	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	5	24	contain	possess	971:977	arg1	composites					960:969	the biomimetic composites	945:969	the biomimetic composites	945:969	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	5	24	contain	possess	971:977	arg2	stiffness					989:997	ultrahigh stiffness	979:997	ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	979:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	1	25	with	materials	172:180	arg1	functionalities					195:209	desired functionalities	187:209	desired functionalities	187:209	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	5	26	theme	tendon	1101:1106	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	7	27	from	materials	1511:1519	arg1	form					1539:1542	practical bulk form	1524:1542	practical bulk form	1524:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	7	28	theme	resilient	1478:1486	arg1	materials					1511:1519	resilient biophotonic structural materials	1478:1519	resilient biophotonic structural materials in practical bulk form	1478:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	4	29	theme	stiff	857:861	arg1	"					871:871	"stiff and hard"	856:871	"stiff and hard"	856:871	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	3	30	theme	carbonate	528:536	arg1	self-assembly					437:449	self-assembly	437:449	self-assembly of cellulose nanocrystals	437:475	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	3	30	theme	carbonate	528:536	arg1	mineralization					492:505	subsequent mineralization	481:505	subsequent mineralization of amorphous calcium carbonate	481:536	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	0	31	theme	Bioinspired	0:10	arg1	Template					19:26	Bioinspired Chiral Template	0:26	Bioinspired Chiral Template	0:26	Bioinspired Chiral Template Guided Mineralization for Biophotonic Structural Materials.					
36208076	1	32	theme	biomineral	113:122	arg1	inspirations					131:142	numerous biomineral design inspirations	104:142	numerous biomineral design inspirations	104:142	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	3	33	theme	cellulose	454:462	arg1	nanocrystals					464:475	cellulose nanocrystals	454:475	cellulose nanocrystals	454:475	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	7	34	theme	biophotonic	1488:1498	arg1	materials					1511:1519	resilient biophotonic structural materials	1478:1519	resilient biophotonic structural materials in practical bulk form	1478:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	4	35	theme	hard	867:870	arg1	"					871:871	"stiff and hard"	856:871	"stiff and hard"	856:871	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	3	36	theme	biomimetic	563:572	arg1	materials					574:582	biomimetic materials	563:582	biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials	563:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	5	37	theme	exoskeleton	1077:1087	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	7	38	from	form	1539:1542	arg1	synthesis					1465:1473	a scalable synthesis	1454:1473	a scalable synthesis of resilient biophotonic structural materials in practical bulk form	1454:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	3	39	theme	amorphous	510:518	arg1	carbonate					528:536	amorphous calcium carbonate	510:536	amorphous calcium carbonate	510:536	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	2	40	theme	large-scale	221:231	arg1	production					233:242	large-scale production	221:242	large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics	221:331	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	3	41	theme	exceptional	592:602	arg1	combination					604:614	an exceptional combination	589:614	an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials	589:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	5	42	theme	crab	1072:1075	arg1	exoskeleton					1077:1087	hydrated crab exoskeleton	1063:1087	hydrated crab exoskeleton	1063:1087	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	6	43	theme	chiral	1258:1263	arg1	color					1276:1280	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	color	1276:1280	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	43	theme	chiral	1258:1263	arg1	absent					1332:1337	absent	1332:1337	absent	1332:1337	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	2	44	theme	Bouligand	263:271	arg1	materials					284:292	damage-tolerant Bouligand structural materials	247:292	damage-tolerant Bouligand structural materials	247:292	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	5	45	theme	synthetic	1122:1130	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	4	46	theme	tunable	750:756	arg1	mechanics					758:766	tunable mechanics	750:766	tunable mechanics	750:766	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	3	47	theme	properties	643:652	arg1	combination					604:614	an exceptional combination	589:614	an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials	589:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	0	48	theme	Biophotonic	54:64	arg1	Materials					77:85	Biophotonic Structural Materials	54:85	Biophotonic Structural Materials	54:85	Bioinspired Chiral Template Guided Mineralization for Biophotonic Structural Materials.					
36208076	4	49	theme	flexible	785:792	arg1	"					793:793	"strong and flexible"	773:793	"strong and flexible"	773:793	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	6	50	theme	unique	1392:1397	arg1	properties					1412:1421	unique hydroplastic properties	1392:1421	unique hydroplastic properties	1392:1421	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	51	theme	water-triggered	1286:1300	arg1	photonics					1313:1321	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	photonics	1313:1321	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	2	52	theme	comparable	312:321	arg1	photonics					323:331	biologically comparable photonics	299:331	biologically comparable photonics	299:331	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	5	53	theme	biomimetic	949:958	arg1	composites					960:969	the biomimetic composites	945:969	the biomimetic composites	945:969	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	4	54	theme	strong	774:779	arg1	"					793:793	"strong and flexible"	773:793	"strong and flexible"	773:793	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	5	55	theme	water-swollen	1023:1035	arg1	value					1045:1049	their fully water-swollen state-a value	1011:1049	their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	1011:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	3	56	theme	scalable	390:397	arg1	strategy					418:425	an efficient and scalable artificial molting strategy	373:425	an efficient and scalable artificial molting strategy	373:425	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	7	57	theme	bulk	1534:1537	arg1	form					1539:1542	practical bulk form	1524:1542	practical bulk form	1524:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	4	58	theme	chiral	835:840	arg1	materials					842:850	natural chiral materials	827:850	natural chiral materials	827:850	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	2	59	theme	longstanding	343:354	arg1	challenge					356:364	a longstanding challenge	341:364	a longstanding challenge	341:364	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	1	60	theme	structural	161:170	arg1	materials					172:180	structural materials	161:180	structural materials with desired functionalities	161:209	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	3	61	theme	efficient	376:384	arg1	strategy					418:425	an efficient and scalable artificial molting strategy	373:425	an efficient and scalable artificial molting strategy	373:425	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	6	62	theme	artificial	1347:1356	arg1	materials					1370:1378	most artificial mineralized materials	1342:1378	most artificial mineralized materials	1342:1378	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	2	63	with	production	233:242	arg1	photonics					323:331	biologically comparable photonics	299:331	biologically comparable photonics	299:331	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	5	64	theme	2 GPa	1002:1006	arg1	stiffness					989:997	ultrahigh stiffness	979:997	ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience	979:1191	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	7	65	theme	structural	1500:1509	arg1	materials					1511:1519	resilient biophotonic structural materials	1478:1519	resilient biophotonic structural materials in practical bulk form	1478:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	3	66	theme	molting	410:416	arg1	strategy					418:425	an efficient and scalable artificial molting strategy	373:425	an efficient and scalable artificial molting strategy	373:425	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	5	67	dep	well	1051:1054	arg1	beyond					1056:1061	beyond	1056:1061	beyond	1056:1061	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	6	68	from	absent	1332:1337	arg1	materials					1370:1378	most artificial mineralized materials	1342:1378	most artificial mineralized materials	1342:1378	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	0	69	theme	Chiral	12:17	arg1	Template					19:26	Bioinspired Chiral Template	0:26	Bioinspired Chiral Template	0:26	Bioinspired Chiral Template Guided Mineralization for Biophotonic Structural Materials.					
36208076	1	70	theme	numerous	104:111	arg1	inspirations					131:142	numerous biomineral design inspirations	104:142	numerous biomineral design inspirations	104:142	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	7	71	theme	scalable	1456:1463	arg1	synthesis					1465:1473	a scalable synthesis	1454:1473	a scalable synthesis of resilient biophotonic structural materials in practical bulk form	1454:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	3	72	theme	subsequent	481:490	arg1	mineralization					492:505	subsequent mineralization	481:505	subsequent mineralization of amorphous calcium carbonate	481:536	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	3	73	from	materials	703:711	arg1	exclusive					680:688	exclusive	680:688	exclusive	680:688	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	1	74	theme	design	124:129	arg1	inspirations					131:142	numerous biomineral design inspirations	104:142	numerous biomineral design inspirations	104:142	Nature provides numerous biomineral design inspirations for constructing structural materials with desired functionalities.					
36208076	3	75	theme	nanocrystals	464:475	arg1	self-assembly					437:449	self-assembly	437:449	self-assembly of cellulose nanocrystals	437:475	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	3	75	theme	nanocrystals	464:475	arg1	mineralization					492:505	subsequent mineralization	481:505	subsequent mineralization of amorphous calcium carbonate	481:536	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	3	76	theme	calcium	520:526	arg1	carbonate					528:536	amorphous calcium carbonate	510:536	amorphous calcium carbonate	510:536	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
36208076	4	77	theme	synthetic	909:917	arg1	counterparts					919:930	natural and synthetic counterparts	897:930	natural and synthetic counterparts	897:930	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	0	78	theme	Structural	66:75	arg1	Materials					77:85	Biophotonic Structural Materials	54:85	Biophotonic Structural Materials	54:85	Bioinspired Chiral Template Guided Mineralization for Biophotonic Structural Materials.					
36208076	6	79	theme	structural	1265:1274	arg1	color					1276:1280	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	color	1276:1280	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	79	theme	structural	1265:1274	arg1	absent					1332:1337	absent	1332:1337	absent	1332:1337	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	2	80	theme	structural	273:282	arg1	materials					284:292	damage-tolerant Bouligand structural materials	247:292	damage-tolerant Bouligand structural materials	247:292	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	6	81	theme	tunable	1250:1256	arg1	color					1276:1280	the tunable chiral structural color and water-triggered switchable photonics	1246:1321	color	1276:1280	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	6	81	theme	tunable	1250:1256	arg1	absent					1332:1337	absent	1332:1337	absent	1332:1337	Additionally, these composites are distinguished by the tunable chiral structural color and water-triggered switchable photonics that are absent in most artificial mineralized materials, as well as unique hydroplastic properties.					
36208076	2	82	theme	damage-tolerant	247:261	arg1	materials					284:292	damage-tolerant Bouligand structural materials	247:292	damage-tolerant Bouligand structural materials	247:292	However, large-scale production of damage-tolerant Bouligand structural materials with biologically comparable photonics remains a longstanding challenge.					
36208076	5	83	theme	stiffest	1113:1120	arg1	hydrogels					1132:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels	1063:1140	Especially, the biomimetic composites possess ultrahigh stiffness of 2 GPa in their fully water-swollen state-a value well beyond hydrated crab exoskeleton, cartilage, tendon, and stiffest synthetic hydrogels, combined with exceptional strength and resilience.					
36208076	7	84	from	synthesis	1465:1473	arg1	form					1539:1542	practical bulk form	1524:1542	practical bulk form	1524:1542	This study opens the door for a scalable synthesis of resilient biophotonic structural materials in practical bulk form.					
36208076	4	85	theme	natural	897:903	arg1	counterparts					919:930	natural and synthetic counterparts	897:930	natural and synthetic counterparts	897:930	These biomimetic composites exhibit tunable mechanics from "strong and flexible", which exceeds the benchmark of natural chiral materials, to "stiff and hard", which is comparable to natural and synthetic counterparts.					
36208076	3	86	theme	photonic	634:641	arg1	properties					643:652	mechanical and photonic properties	619:652	mechanical and photonic properties that are usually mutually exclusive in synthetic materials	619:711	Here, an efficient and scalable artificial molting strategy, based on self-assembly of cellulose nanocrystals and subsequent mineralization of amorphous calcium carbonate, is developed to produce biomimetic materials with an exceptional combination of mechanical and photonic properties that are usually mutually exclusive in synthetic materials.					
35914454	4	0	theme	luteolin	1015:1022	arg1	detection					1024:1032	luteolin detection	1015:1032	luteolin detection	1015:1032	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	4	1	theme	common	994:999	arg1	ions					1007:1010	common metal ions	994:1010	common metal ions	994:1010	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	3	2	theme	linear	803:808	arg1	range					810:814	a wide linear range	796:814	a wide linear range of 0.4 nM -1800 nM	796:833	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	2	3	theme	metal-organic	496:508	arg1	CD-MOF					520:525	CD-MOF	520:525	CD-MOF	520:525	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	3	theme	metal-organic	496:508	arg1	framework					510:518	γ-cyclodextrin metal-organic framework	481:518	γ-cyclodextrin metal-organic framework(CD-MOF)	481:526	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	1	4	theme	Chrysanthemum	195:207	arg1	tea					209:211	Chrysanthemum tea	195:211	Chrysanthemum tea	195:211	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	4	theme	Chrysanthemum	195:207	arg1	drink					246:250	a tranditional Chinese health drink	216:250	a tranditional Chinese health drink	216:250	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	0	5	theme	MoO3/poly	102:110	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	0	6	from	Determination	0:12	arg1	tea					43:45	Chrysanthemum tea	29:45	Chrysanthemum tea with a ultra-sensitive electrochemical sensor	29:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	2	7	dep	fourier	651:657	arg1	transform					659:667	transform	659:667	transform infrared (FTIR)	659:683	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	5	8	theme	luteolin	1160:1167	arg1	detection					1147:1155	the detection	1143:1155	the detection of luteolin in real Chrysanthemum tea samples	1143:1201	Finally, the sensor was successfully applied to the detection of luteolin in real Chrysanthemum tea samples.					
35914454	2	9	theme	prepared.The	532:543	arg1	materials					545:553	prepared.The materials	532:553	prepared.The materials	532:553	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	3	10	theme	optimized	906:914	arg1	conditions					916:925	optimized conditions	906:925	optimized conditions	906:925	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	1	11	theme	vesatile	295:302	arg1	benefit					311:317	vesatile health benefit	295:317	vesatile health benefit activities	295:328	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	0	12	theme	3,4-ethylene	112:123	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	4	13	theme	ions	1007:1010	arg1	influences					941:950	the influences	937:950	the influences of some coexistent phenolic compounds and common metal ions on luteolin detection	937:1032	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	3	14	theme	wide	798:801	arg1	range					810:814	a wide linear range	796:814	a wide linear range of 0.4 nM -1800 nM	796:833	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	4	15	theme	phenolic	971:978	arg1	compounds					980:988	some coexistent phenolic compounds	955:988	some coexistent phenolic compounds	955:988	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	2	16	theme	sensitive	341:349	arg1	sensor					367:372	A sensitive electrochemical sensor	339:372	A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF)	339:526	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	17	theme	electron	599:606	arg1	SEM					620:622	SEM	620:622	SEM	620:622	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	17	theme	electron	599:606	arg1	microscopy					608:617	scanning electron microscopy	590:617	scanning electron microscopy (SEM)	590:623	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	4	18	theme	coexistent	960:969	arg1	compounds					980:988	some coexistent phenolic compounds	955:988	some coexistent phenolic compounds	955:988	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	1	19	theme	health	304:309	arg1	benefit					311:317	vesatile health benefit	295:317	vesatile health benefit activities	295:328	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	2	20	theme	X-ray	626:630	arg1	diffraction					632:642	X-ray diffraction	626:642	X-ray diffraction (XRD)	626:648	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	20	theme	X-ray	626:630	arg1	XRD					645:647	XRD	645:647	XRD	645:647	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	4	21	theme	significant	1056:1066	arg1	interference					1068:1079	no significant interference	1053:1079	no significant interference	1053:1079	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	1	22	theme	tranditional	218:229	arg1	tea					209:211	Chrysanthemum tea	195:211	Chrysanthemum tea	195:211	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	22	theme	tranditional	218:229	arg1	drink					246:250	a tranditional Chinese health drink	216:250	a tranditional Chinese health drink	216:250	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	23	theme	benefit	311:317	arg1	activities					319:328	vesatile health benefit activities	295:328	vesatile health benefit activities	295:328	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	24	theme	Chinese	231:237	arg1	tea					209:211	Chrysanthemum tea	195:211	Chrysanthemum tea	195:211	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	24	theme	Chinese	231:237	arg1	drink					246:250	a tranditional Chinese health drink	216:250	a tranditional Chinese health drink	216:250	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	0	25	theme	luteolin	17:24	arg1	Determination					0:12	Determination	0:12	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor	0:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	0	26	theme	dioxythiophene	125:138	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	2	27	theme	composite	383:391	arg1	materials					393:401	composite materials	383:401	composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF)	383:526	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	3	28	theme	0.1 nM	870:875	arg1	limit					855:859	a low detection limit	839:859	a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin	839:898	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	28	theme	0.1 nM	870:875	arg1	S/N = 3					878:884	S/N = 3	878:884	S/N = 3	878:884	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	28	theme	0.1 nM	870:875	arg1	LOD					862:864	LOD	862:864	LOD	862:864	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	28	theme	0.1 nM	870:875	arg1	range					810:814	a wide linear range	796:814	a wide linear range of 0.4 nM -1800 nM	796:833	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	1	29	theme	health	239:244	arg1	tea					209:211	Chrysanthemum tea	195:211	Chrysanthemum tea	195:211	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	29	theme	health	239:244	arg1	drink					246:250	a tranditional Chinese health drink	216:250	a tranditional Chinese health drink	216:250	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	2	30	theme	γ-cyclodextrin	481:494	arg1	CD-MOF					520:525	CD-MOF	520:525	CD-MOF	520:525	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	30	theme	γ-cyclodextrin	481:494	arg1	framework					510:518	γ-cyclodextrin metal-organic framework	481:518	γ-cyclodextrin metal-organic framework(CD-MOF)	481:526	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	0	31	theme	metal-organic	159:171	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	2	32	dep	3	438:438	arg1	dioxyethiophene					452:466	4-ethylene dioxyethiophene	441:466	4-ethylene dioxyethiophene	441:466	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	33	theme	MoO3	417:420	arg1	nanorods					422:429	MoO3 nanorods	417:429	MoO3 nanorods	417:429	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	0	34	theme	Chrysanthemum	29:41	arg1	tea					43:45	Chrysanthemum tea	29:45	Chrysanthemum tea with a ultra-sensitive electrochemical sensor	29:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	0	35	theme	/gama-cyclodextrin	140:157	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	5	36	from	detection	1147:1155	arg1	samples					1195:1201	real Chrysanthemum tea samples	1172:1201	real Chrysanthemum tea samples	1172:1201	Finally, the sensor was successfully applied to the detection of luteolin in real Chrysanthemum tea samples.					
35914454	4	37	theme	metal	1001:1005	arg1	ions					1007:1010	common metal ions	994:1010	common metal ions	994:1010	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	2	38	theme	photoelectron	696:708	arg1	XPS					724:726	XPS	724:726	XPS	724:726	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	38	theme	photoelectron	696:708	arg1	spectroscopy					710:721	X-ray photoelectron spectroscopy	690:721	X-ray photoelectron spectroscopy (XPS)	690:727	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	3	39	theme	materials	767:775	arg1	synergisticeffects					741:758	the synergisticeffects	737:758	the synergisticeffects of the materials	737:775	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	1	40	contain	contains	259:266	arg2	flavonoid					280:288	a flavonoid	278:288	a flavonoid with vesatile health benefit activities	278:328	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	40	contain	contains	259:266	arg1	drink					246:250	a tranditional Chinese health drink	216:250	a tranditional Chinese health drink	216:250	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	40	contain	contains	259:266	arg1	tea					209:211	Chrysanthemum tea	195:211	Chrysanthemum tea	195:211	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	1	40	contain	contains	259:266	arg2	luteolin					268:275	luteolin	268:275	luteolin	268:275	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	2	41	theme	X-ray	690:694	arg1	XPS					724:726	XPS	724:726	XPS	724:726	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	41	theme	X-ray	690:694	arg1	spectroscopy					710:721	X-ray photoelectron spectroscopy	690:721	X-ray photoelectron spectroscopy (XPS)	690:727	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	4	42	from	influences	941:950	arg1	detection					1024:1032	luteolin detection	1015:1032	luteolin detection	1015:1032	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	0	43	theme	framework	173:181	arg1	composites					183:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites	102:192	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	3	44	theme	-1800 nM	826:833	arg1	limit					855:859	a low detection limit	839:859	a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin	839:898	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	44	theme	-1800 nM	826:833	arg1	S/N = 3					878:884	S/N = 3	878:884	S/N = 3	878:884	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	44	theme	-1800 nM	826:833	arg1	LOD					862:864	LOD	862:864	LOD	862:864	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	44	theme	-1800 nM	826:833	arg1	range					810:814	a wide linear range	796:814	a wide linear range of 0.4 nM -1800 nM	796:833	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	2	45	theme	scanning	590:597	arg1	SEM					620:622	SEM	620:622	SEM	620:622	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	2	45	theme	scanning	590:597	arg1	microscopy					608:617	scanning electron microscopy	590:617	scanning electron microscopy (SEM)	590:623	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	1	46	with	flavonoid	280:288	arg1	activities					319:328	vesatile health benefit activities	295:328	vesatile health benefit activities	295:328	Chrysanthemum tea is a tranditional Chinese health drink, which contains luteolin, a flavonoid with vesatile health benefit activities.					
35914454	2	47	dep	infrared	669:676	arg1	FTIR					679:682	FTIR	679:682	FTIR	679:682	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	5	48	theme	real	1172:1175	arg1	samples					1195:1201	real Chrysanthemum tea samples	1172:1201	real Chrysanthemum tea samples	1172:1201	Finally, the sensor was successfully applied to the detection of luteolin in real Chrysanthemum tea samples.					
35914454	2	49	theme	electrochemical	351:365	arg1	sensor					367:372	A sensitive electrochemical sensor	339:372	A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF)	339:526	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	5	50	theme	Chrysanthemum	1177:1189	arg1	samples					1195:1201	real Chrysanthemum tea samples	1172:1201	real Chrysanthemum tea samples	1172:1201	Finally, the sensor was successfully applied to the detection of luteolin in real Chrysanthemum tea samples.					
35914454	0	51	theme	electrochemical	70:84	arg1	sensor					86:91	a ultra-sensitive electrochemical sensor	52:91	a ultra-sensitive electrochemical sensor	52:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	3	52	theme	low	841:843	arg1	S/N = 3					878:884	S/N = 3	878:884	S/N = 3	878:884	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	52	theme	low	841:843	arg1	LOD					862:864	LOD	862:864	LOD	862:864	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	52	theme	low	841:843	arg1	limit					855:859	a low detection limit	839:859	a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin	839:898	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	2	53	theme	4-ethylene	441:450	arg1	dioxyethiophene					452:466	4-ethylene dioxyethiophene	441:466	4-ethylene dioxyethiophene	441:466	Herein, A sensitive electrochemical sensor based on composite materials consisting of MoO3 nanorods, poly (3, 4-ethylene dioxyethiophene)(PEDOT), and γ-cyclodextrin metal-organic framework(CD-MOF) was prepared.The materials were characterized and analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS).					
35914454	3	54	theme	0.4 nM	819:824	arg1	-1800 nM					826:833	0.4 nM -1800 nM	819:833	0.4 nM -1800 nM	819:833	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	5	55	theme	tea	1191:1193	arg1	samples					1195:1201	real Chrysanthemum tea samples	1172:1201	real Chrysanthemum tea samples	1172:1201	Finally, the sensor was successfully applied to the detection of luteolin in real Chrysanthemum tea samples.					
35914454	0	56	theme	ultra-sensitive	54:68	arg1	sensor					86:91	a ultra-sensitive electrochemical sensor	52:91	a ultra-sensitive electrochemical sensor	52:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	4	57	theme	compounds	980:988	arg1	influences					941:950	the influences	937:950	the influences of some coexistent phenolic compounds and common metal ions on luteolin detection	937:1032	Besides, the influences of some coexistent phenolic compounds and common metal ions on luteolin detection were evaluated and no significant interference was observed.					
35914454	0	58	with	tea	43:45	arg1	sensor					86:91	a ultra-sensitive electrochemical sensor	52:91	a ultra-sensitive electrochemical sensor	52:91	Determination of luteolin in Chrysanthemum tea with a ultra-sensitive electrochemical sensor based on MoO3/poly(3,4-ethylene dioxythiophene)/gama-cyclodextrin metal-organic framework composites.					
35914454	3	59	theme	detection	845:853	arg1	S/N = 3					878:884	S/N = 3	878:884	S/N = 3	878:884	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	59	theme	detection	845:853	arg1	LOD					862:864	LOD	862:864	LOD	862:864	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
35914454	3	59	theme	detection	845:853	arg1	limit					855:859	a low detection limit	839:859	a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin	839:898	Due to the synergisticeffects of the materials, the sensor showed a wide linear range of 0.4 nM -1800 nM and a low detection limit (LOD) of 0.1 nM (S/N = 3) for luteolin under optimized conditions.					
36555563	0	0	theme	alcohol	69:75	arg1	Properties					13:22	Properties	13:22	Properties	13:22	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	0	0	theme	alcohol	69:75	arg1	Mechanism					29:37	Mechanism	29:37	Mechanism	29:37	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	0	0	theme	alcohol	69:75	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	4	1	theme	PVA	835:837	arg1	chains					839:844	PVA chains	835:844	PVA chains	835:844	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	2	2	theme	pure	591:594	arg1	aerogel					600:606	the pure PVA aerogel	587:606	the pure PVA aerogel	587:606	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	6	3	theme	advantageous	1137:1148	arg1	strategy					1150:1157	This mutually advantageous strategy	1123:1157	This mutually advantageous strategy	1123:1157	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	0	4	theme	vinyl	63:67	arg1	alcohol					69:75	Flame-Retardant Poly(vinyl alcohol)	42:76	Flame-Retardant Poly(vinyl alcohol)	42:76	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	3	5	dep	%	699:699	arg1	to					701:702	to	701:702	to	701:702	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	4	6	theme	mechanistic	715:725	arg1	study					727:731	The mechanistic study	711:731	The mechanistic study of flame retardancy	711:751	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	3	7	theme	18.1	695:698	arg1	%					699:699	%	699:699	%	699:699	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	2	8	theme	aerogel	508:514	arg1	rate					405:408	The peak heat release rate	383:408	The peak heat release rate (PHRR)	383:415	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	8	theme	aerogel	508:514	arg1	production					452:461	CO production	449:461	CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel	449:514	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	8	theme	aerogel	508:514	arg1	release					430:436	total smoke release	418:436	total smoke release (TSR)	418:442	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	8	theme	aerogel	508:514	arg1	PHRR					411:414	PHRR	411:414	PHRR	411:414	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	8	theme	aerogel	508:514	arg1	TSR					439:441	TSR	439:441	TSR	439:441	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	8	theme	aerogel	508:514	arg1	COP					464:466	COP	464:466	COP	464:466	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	1	9	with	aerogels	279:286	arg1	retardancy					325:334	excellent flame retardancy	309:334	excellent flame retardancy	309:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	4	10	theme	combustible	983:993	arg1	gases					1001:1005	combustible toxic gases	983:1005	combustible toxic gases (CO2, CO)	983:1015	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	2	11	theme	CO	449:450	arg1	COP					464:466	COP	464:466	COP	464:466	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	11	theme	CO	449:450	arg1	production					452:461	CO production	449:461	CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel	449:514	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	1	12	theme	excellent	309:317	arg1	retardancy					325:334	excellent flame retardancy	309:334	excellent flame retardancy	309:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	2	13	theme	composite	498:506	arg1	aerogel					508:514	the (PVA/PCF10/α-ZrP10-3) composite aerogel	472:514	the (PVA/PCF10/α-ZrP10-3) composite aerogel	472:514	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	4	14	theme	chains	839:844	arg1	carbonization					818:830	carbonization	818:830	carbonization	818:830	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	4	14	theme	chains	839:844	arg1	crosslinking					801:812	crosslinking	801:812	crosslinking	801:812	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	6	15	theme	new	1168:1170	arg1	strategy					1172:1179	a new strategy	1166:1179	a new strategy for the preparation of composite aerogels with enhanced fire resistance	1166:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	1	16	theme	flame	319:323	arg1	retardancy					325:334	excellent flame retardancy	309:334	excellent flame retardancy	309:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	0	17	dep	Aerogels	78:85	arg1	Based					87:91	Based	87:91	Aerogels Based on the Multi-Directional Freezing Method	78:132	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	6	18	theme	composite	1204:1212	arg1	aerogels					1214:1221	composite aerogels	1204:1221	composite aerogels with enhanced fire resistance	1204:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	1	19	theme	exfoliated	149:158	arg1	α-ZrP					183:187	α-ZrP	183:187	α-ZrP	183:187	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	19	theme	exfoliated	149:158	arg1	phosphate					172:180	exfoliated α-zirconium phosphate	149:180	exfoliated α-zirconium phosphate (α-ZrP)	149:188	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	20	theme	α-zirconium	160:170	arg1	α-ZrP					183:187	α-ZrP	183:187	α-ZrP	183:187	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	20	theme	α-zirconium	160:170	arg1	phosphate					172:180	exfoliated α-zirconium phosphate	149:180	exfoliated α-zirconium phosphate (α-ZrP)	149:188	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	6	21	theme	fire	1237:1240	arg1	resistance					1242:1251	enhanced fire resistance	1228:1251	enhanced fire resistance	1228:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	1	22	theme	poly	249:252	arg1	PVA/PCF/α-ZrP					289:301	PVA/PCF/α-ZrP	289:301	PVA/PCF/α-ZrP	289:301	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	22	theme	poly	249:252	arg1	aerogels					279:286	poly(vinyl alcohol) composite aerogels	249:286	poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy	249:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	0	23	theme	Multi-Directional	100:116	arg1	Method					127:132	the Multi-Directional Freezing Method	96:132	the Multi-Directional Freezing Method	96:132	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	2	24	theme	heat	392:395	arg1	PHRR					411:414	PHRR	411:414	PHRR	411:414	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	24	theme	heat	392:395	arg1	rate					405:408	The peak heat release rate	383:408	The peak heat release rate (PHRR)	383:415	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	25	theme	release	397:403	arg1	PHRR					411:414	PHRR	411:414	PHRR	411:414	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	25	theme	release	397:403	arg1	rate					405:408	The peak heat release rate	383:408	The peak heat release rate (PHRR)	383:415	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	26	theme	peak	387:390	arg1	PHRR					411:414	PHRR	411:414	PHRR	411:414	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	26	theme	peak	387:390	arg1	rate					405:408	The peak heat release rate	383:408	The peak heat release rate (PHRR)	383:415	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	27	theme	smoke	424:428	arg1	TSR					439:441	TSR	439:441	TSR	439:441	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	27	theme	smoke	424:428	arg1	release					430:436	total smoke release	418:436	total smoke release (TSR)	418:442	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	1	28	theme	vinyl	254:258	arg1	poly					249:252	poly	249:252	poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy	249:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	28	theme	vinyl	254:258	arg1	alcohol					260:266	vinyl alcohol	254:266	vinyl alcohol	254:266	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	29	theme	multi-directional	348:364	arg1	method					375:380	the multi-directional freezing method	344:380	the multi-directional freezing method	344:380	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	4	30	dep	gases	1001:1005	arg1	CO					1013:1014	CO	1013:1014	CO	1013:1014	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	4	30	dep	gases	1001:1005	arg1	CO2					1008:1010	CO2	1008:1010	CO2	1008:1010	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	2	31	theme	total	418:422	arg1	TSR					439:441	TSR	439:441	TSR	439:441	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	2	31	theme	total	418:422	arg1	release					430:436	total smoke release	418:436	total smoke release (TSR)	418:442	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	3	32	theme	oxygen	652:657	arg1	value					671:675	the limiting oxygen index (LOI) value	639:675	the limiting oxygen index (LOI) value	639:675	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	0	33	theme	Freezing	118:125	arg1	Method					127:132	the Multi-Directional Freezing Method	96:132	the Multi-Directional Freezing Method	96:132	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	1	34	theme	freezing	366:373	arg1	method					375:380	the multi-directional freezing method	344:380	the multi-directional freezing method	344:380	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	0	35	theme	Flame-Retardant	42:56	arg1	alcohol					69:75	Flame-Retardant Poly(vinyl alcohol)	42:76	Flame-Retardant Poly(vinyl alcohol)	42:76	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	3	36	theme	index	659:663	arg1	value					671:675	the limiting oxygen index (LOI) value	639:675	the limiting oxygen index (LOI) value	639:675	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	4	37	theme	flame	736:740	arg1	retardancy					742:751	flame retardancy	736:751	flame retardancy	736:751	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	6	38	theme	aerogels	1214:1221	arg1	preparation					1189:1199	the preparation	1185:1199	the preparation of composite aerogels with enhanced fire resistance	1185:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	4	39	theme	gases	1001:1005	arg1	emissions					970:978	the emissions	966:978	the emissions of combustible toxic gases (CO2, CO)	966:1015	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	6	40	theme	enhanced	1228:1235	arg1	resistance					1242:1251	enhanced fire resistance	1228:1251	enhanced fire resistance	1228:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	1	41	theme	composite	269:277	arg1	PVA/PCF/α-ZrP					289:301	PVA/PCF/α-ZrP	289:301	PVA/PCF/α-ZrP	289:301	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	41	theme	composite	269:277	arg1	aerogels					279:286	poly(vinyl alcohol) composite aerogels	249:286	poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy	249:334	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	4	42	dep	crosslinking	801:812	arg1	the					797:799	the	797:799	the	797:799	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	3	43	theme	28.4	704:707	arg1	%					699:699	%	699:699	%	699:699	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	3	44	theme	limiting	643:650	arg1	value					671:675	the limiting oxygen index (LOI) value	639:675	the limiting oxygen index (LOI) value	639:675	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36555563	6	45	with	aerogels	1214:1221	arg1	resistance					1242:1251	enhanced fire resistance	1228:1251	enhanced fire resistance	1228:1251	This mutually advantageous strategy offers a new strategy for the preparation of composite aerogels with enhanced fire resistance.					
36555563	4	46	theme	toxic	995:999	arg1	gases					1001:1005	combustible toxic gases	983:1005	combustible toxic gases (CO2, CO)	983:1015	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	1	47	theme	phosphated	194:203	arg1	PCF					216:218	PCF	216:218	PCF	216:218	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	1	47	theme	phosphated	194:203	arg1	cellulose					205:213	phosphated cellulose	194:213	phosphated cellulose (PCF)	194:219	In this work, exfoliated α-zirconium phosphate (α-ZrP) and phosphated cellulose (PCF) were employed to synthesize poly(vinyl alcohol) composite aerogels (PVA/PCF/α-ZrP) with excellent flame retardancy through the multi-directional freezing method.					
36555563	4	48	theme	retardancy	742:751	arg1	study					727:731	The mechanistic study	711:731	The mechanistic study of flame retardancy	711:751	The mechanistic study of flame retardancy showed evidence that PCF and α-ZrP promoted the crosslinking and carbonization of PVA chains to form a barrier, which not only served as insulation between the material and the air, but also significantly reduced the emissions of combustible toxic gases (CO2, CO).					
36555563	5	49	theme	carbonization	1100:1112	arg1	process					1114:1120	the catalytic carbonization process	1086:1120	the catalytic carbonization process	1086:1120	In addition, the multi-directional freezing method further improved the catalytic carbonization process.					
36555563	5	50	theme	catalytic	1090:1098	arg1	process					1114:1120	the catalytic carbonization process	1086:1120	the catalytic carbonization process	1086:1120	In addition, the multi-directional freezing method further improved the catalytic carbonization process.					
36555563	0	51	theme	Poly	58:61	arg1	alcohol					69:75	Flame-Retardant Poly(vinyl alcohol)	42:76	Flame-Retardant Poly(vinyl alcohol)	42:76	Preparation, Properties, and Mechanism of Flame-Retardant Poly(vinyl alcohol) Aerogels Based on the Multi-Directional Freezing Method.					
36555563	5	52	theme	multi-directional	1035:1051	arg1	method					1062:1067	the multi-directional freezing method	1031:1067	the multi-directional freezing method	1031:1067	In addition, the multi-directional freezing method further improved the catalytic carbonization process.					
36555563	2	53	theme	PVA	596:598	arg1	aerogel					600:606	the pure PVA aerogel	587:606	the pure PVA aerogel	587:606	The peak heat release rate (PHRR), total smoke release (TSR), and CO production (COP) of the (PVA/PCF10/α-ZrP10-3) composite aerogel were considerably decreased by 42.3%, 41.4%, and 34.7%, as compared to the pure PVA aerogel, respectively.					
36555563	5	54	theme	freezing	1053:1060	arg1	method					1062:1067	the multi-directional freezing method	1031:1067	the multi-directional freezing method	1031:1067	In addition, the multi-directional freezing method further improved the catalytic carbonization process.					
36555563	3	55	theme	LOI	666:668	arg1	value					671:675	the limiting oxygen index (LOI) value	639:675	the limiting oxygen index (LOI) value	639:675	Simultaneously, the limiting oxygen index (LOI) value was improved from 18.1% to 28.4%.					
36933468	0	0	theme	gels	93:96	arg1	fabrication					8:18	In-situ fabrication	0:18	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	0:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	3	1	theme	targeting	682:690	arg1	function					692:699	targeting function	682:699	targeting function	682:699	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	2	2	theme	ferroptosis	569:579	arg1	glutathione					512:522	glutathione	512:522	glutathione (GSH)	512:528	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	2	theme	ferroptosis	569:579	arg1	GSH					525:527	GSH	525:527	GSH	525:527	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	2	theme	ferroptosis	569:579	arg1	H2O2					502:505	H2O2	502:505	H2O2	502:505	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	2	theme	ferroptosis	569:579	arg1	existence					480:488	the excessive existence	466:488	the excessive existence of H+ ions	466:499	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	2	theme	ferroptosis	569:579	arg1	lack					535:538	the lack	531:538	the lack of O2	531:544	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	2	theme	ferroptosis	569:579	arg1	relaxation					555:564	the relaxation	551:564	the relaxation of ferroptosis	551:579	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	3	3	dep	in	758:759	arg1	situ					761:764	situ	761:764	situ	761:764	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	1	4	theme	Multimodal	209:218	arg1	MCT					238:240	MCT	238:240	MCT	238:240	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	1	4	theme	Multimodal	209:218	arg1	therapy					229:235	Multimodal combined therapy	209:235	Multimodal combined therapy (MCT)	209:241	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	1	4	theme	Multimodal	209:218	arg1	avenue					258:263	an emerging avenue	246:263	an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods	246:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	7	5	theme	research	1647:1654	arg1	avenue					1656:1661	another research avenue	1639:1661	another research avenue for cuproptosis-enhanced PTT/PDT/CDT	1639:1698	Hence, the novel design in our work provides another research avenue for cuproptosis-enhanced PTT/PDT/CDT via TME modulation.					
36933468	3	6	theme	alginate	804:811	arg1	HA					835:836	HA	835:836	HA	835:836	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	6	theme	alginate	804:811	arg1	acid					829:832	sodium alginate (SA)/hyaluronic acid	797:832	sodium alginate (SA)/hyaluronic acid (HA)	797:837	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	0	7	theme	nanohybrid	82:91	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	1	8	theme	combined	220:227	arg1	MCT					238:240	MCT	238:240	MCT	238:240	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	1	8	theme	combined	220:227	arg1	therapy					229:235	Multimodal combined therapy	209:235	Multimodal combined therapy (MCT)	209:241	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	1	8	theme	combined	220:227	arg1	avenue					258:263	an emerging avenue	246:263	an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods	246:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	4	9	theme	photodynamic	1037:1048	arg1	PDT					1059:1061	PDT	1059:1061	PDT	1059:1061	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	9	theme	photodynamic	1037:1048	arg1	therapy					1050:1056	photodynamic therapy	1037:1056	photodynamic therapy (PDT)	1037:1062	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	10	theme	core-shell	884:893	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	5	11	theme	Cu2+	1104:1107	arg1	ions					1109:1112	Cu2+ ions	1104:1112	Cu2+ ions	1104:1112	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	7	12	theme	TME	1704:1706	arg1	modulation					1708:1717	TME modulation	1704:1717	TME modulation	1704:1717	Hence, the novel design in our work provides another research avenue for cuproptosis-enhanced PTT/PDT/CDT via TME modulation.					
36933468	1	13	theme	synergistic	297:307	arg1	effect					309:314	the synergistic effect	293:314	the synergistic effect of various therapeutic methods	293:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	4	14	theme	SA-HA	878:882	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	5	15	from	H2O2	1227:1230	arg1	TME					1239:1241	the TME to generate O2	1235:1256	the TME to generate O2	1235:1256	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	3	16	with	gels	630:633	arg1	stability					668:676	stability	668:676	stability	668:676	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	16	with	gels	630:633	arg1	function					692:699	targeting function	682:699	targeting function	682:699	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	16	with	gels	630:633	arg1	biocompatibility					650:665	excellent biocompatibility	640:665	excellent biocompatibility	640:665	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	17	theme	sodium	797:802	arg1	HA					835:836	HA	835:836	HA	835:836	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	17	theme	sodium	797:802	arg1	acid					829:832	sodium alginate (SA)/hyaluronic acid	797:832	sodium alginate (SA)/hyaluronic acid (HA)	797:837	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	0	18	theme	photothermal/photodynamic/chemodynamic	123:160	arg1	therapy					162:168	photothermal/photodynamic/chemodynamic therapy	123:168	photothermal/photodynamic/chemodynamic therapy	123:168	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	2	19	theme	excessive	470:478	arg1	existence					480:488	the excessive existence	466:488	the excessive existence of H+ ions	466:499	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	0	20	theme	nanoclusters-Cu2+	32:48	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	6	21	theme	chemodynamic	1566:1577	arg1	CDT					1588:1590	CDT	1588:1590	CDT	1588:1590	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	21	theme	chemodynamic	1566:1577	arg1	therapy					1579:1585	chemodynamic therapy	1566:1585	chemodynamic therapy (CDT)	1566:1591	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	4	22	theme	guided	999:1004	arg1	PTT					1028:1030	PTT	1028:1030	PTT	1028:1030	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	22	theme	guided	999:1004	arg1	therapy					1019:1025	guided photothermal therapy	999:1025	guided photothermal therapy (PTT)	999:1031	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	23	theme	@	877:877	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	24	theme	photothermal	1006:1017	arg1	PTT					1028:1030	PTT	1028:1030	PTT	1028:1030	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	24	theme	photothermal	1006:1017	arg1	therapy					1019:1025	guided photothermal therapy	999:1025	guided photothermal therapy (PTT)	999:1031	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	2	25	theme	ions	496:499	arg1	glutathione					512:522	glutathione	512:522	glutathione (GSH)	512:528	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	25	theme	ions	496:499	arg1	GSH					525:527	GSH	525:527	GSH	525:527	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	25	theme	ions	496:499	arg1	H2O2					502:505	H2O2	502:505	H2O2	502:505	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	25	theme	ions	496:499	arg1	existence					480:488	the excessive existence	466:488	the excessive existence of H+ ions	466:499	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	25	theme	ions	496:499	arg1	lack					535:538	the lack	531:538	the lack of O2	531:544	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	25	theme	ions	496:499	arg1	relaxation					555:564	the relaxation	551:564	the relaxation of ferroptosis	551:579	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	5	26	from	gels	1134:1137	arg1	release					1093:1099	the H+-triggered release	1076:1099	the H+-triggered release of Cu2+ ions from the nanohybrid gels	1076:1137	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	5	26	from	gels	1134:1137	arg1	Meanwhile					1065:1073	Meanwhile	1065:1073	Meanwhile	1065:1073	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	4	27	theme	near-infrared	921:933	arg1	response					941:948	near-infrared light response	921:948	near-infrared light response	921:948	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	6	28	theme	Cu+	1405:1407	arg1	ions					1409:1412	Cu+ ions	1405:1412	Cu+ ions	1405:1412	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	29	theme	radicals	1471:1478	arg1	formation					1444:1452	the formation	1440:1452	the formation of hydroxyl free radicals (·OH)	1440:1484	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	2	30	theme	key	414:416	arg1	barrier					418:424	the key barrier	410:424	the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis	410:579	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	0	31	theme	In-situ	0:6	arg1	fabrication					8:18	In-situ fabrication	0:18	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	0:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	6	32	theme	free	1466:1469	arg1	·OH					1481:1483	·OH	1481:1483	·OH	1481:1483	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	32	theme	free	1466:1469	arg1	radicals					1471:1478	hydroxyl free radicals	1457:1478	hydroxyl free radicals (·OH)	1457:1484	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	3	33	theme	nanohybrid	619:628	arg1	gels					630:633	smart nanohybrid gels	613:633	smart nanohybrid gels with excellent biocompatibility, stability and targeting function	613:699	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	0	34	theme	novel	23:27	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	1	35	theme	various	319:325	arg1	methods					339:345	various therapeutic methods	319:345	various therapeutic methods	319:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	4	36	theme	Au	866:867	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	6	37	theme	consumption-enhanced	1537:1556	arg1	PDT					1558:1560	GSH consumption-enhanced PDT	1533:1560	GSH consumption-enhanced PDT	1533:1560	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	38	theme	hydroxyl	1457:1464	arg1	·OH					1481:1483	·OH	1481:1483	·OH	1481:1483	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	38	theme	hydroxyl	1457:1464	arg1	radicals					1471:1478	hydroxyl free radicals	1457:1478	hydroxyl free radicals (·OH)	1457:1484	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	2	39	theme	MCT	455:457	arg1	effect					445:450	the therapeutic effect	429:450	the therapeutic effect of MCT	429:457	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	1	40	theme	therapeutic	327:337	arg1	methods					339:345	various therapeutic methods	319:345	various therapeutic methods	319:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	4	41	theme	obtained	857:864	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	3	42	theme	smart	613:617	arg1	gels					630:633	smart nanohybrid gels	613:633	smart nanohybrid gels with excellent biocompatibility, stability and targeting function	613:699	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	2	43	theme	H+	493:494	arg1	ions					496:499	H+ ions	493:499	H+ ions	493:499	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	1	44	theme	methods	339:345	arg1	effect					309:314	the synergistic effect	293:314	the synergistic effect of various therapeutic methods	293:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	0	45	theme	microenvironment	180:195	arg1	regulation					197:206	tumor microenvironment regulation	174:206	tumor microenvironment regulation	174:206	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	2	46	theme	therapeutic	433:443	arg1	effect					445:450	the therapeutic effect	429:450	the therapeutic effect of MCT	429:457	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	4	47	theme	NCs-Cu2+	869:876	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	1	48	theme	emerging	249:256	arg1	therapy					229:235	Multimodal combined therapy	209:235	Multimodal combined therapy (MCT)	209:241	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	1	48	theme	emerging	249:256	arg1	avenue					258:263	an emerging avenue	246:263	an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods	246:345	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	0	49	theme	Au	29:30	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	4	50	theme	light	935:939	arg1	response					941:948	near-infrared light response	921:948	near-infrared light response	921:948	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	0	51	theme	tumor	174:178	arg1	microenvironment					180:195	tumor microenvironment	174:195	tumor microenvironment regulation	174:206	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	5	52	theme	ferroptosis	1195:1205	arg1	relaxation					1181:1190	the relaxation	1177:1190	the relaxation of ferroptosis	1177:1205	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	6	53	theme	GSH	1533:1535	arg1	PDT					1558:1560	GSH consumption-enhanced PDT	1533:1560	GSH consumption-enhanced PDT	1533:1560	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	4	54	theme	nanohybrid	895:904	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	0	55	theme	sodium	50:55	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	3	56	theme	in	758:759	arg1	nanoclusters					729:740	gold nanoclusters	724:740	gold nanoclusters	724:740	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	56	theme	in	758:759	arg1	gel					790:792	an in situ cross-linking composite gel	755:792	an in situ cross-linking composite gel	755:792	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	7	57	from	design	1611:1616	arg1	work					1625:1628	our work	1621:1628	our work	1621:1628	Hence, the novel design in our work provides another research avenue for cuproptosis-enhanced PTT/PDT/CDT via TME modulation.					
36933468	3	58	theme	gold	724:727	arg1	nanoclusters					729:740	gold nanoclusters	724:740	gold nanoclusters	724:740	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	58	theme	gold	724:727	arg1	gel					790:792	an in situ cross-linking composite gel	755:792	an in situ cross-linking composite gel	755:792	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	58	theme	gold	724:727	arg1	shell					846:850	the shell	842:850	the shell	842:850	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	58	theme	gold	724:727	arg1	cores					745:749	cores	745:749	cores	745:749	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	5	59	dep	microenvironment	1296:1311	arg1	effect					1321:1326	effect	1321:1326	effect	1321:1326	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	0	60	theme	@	49:49	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	3	61	theme	excellent	640:648	arg1	biocompatibility					650:665	excellent biocompatibility	640:665	excellent biocompatibility	640:665	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	5	62	theme	ions	1109:1112	arg1	release					1093:1099	the H+-triggered release	1076:1099	the H+-triggered release of Cu2+ ions from the nanohybrid gels	1076:1137	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	5	62	theme	ions	1109:1112	arg1	Meanwhile					1065:1073	Meanwhile	1065:1073	Meanwhile	1065:1073	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	3	63	theme	/hyaluronic	817:827	arg1	HA					835:836	HA	835:836	HA	835:836	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	63	theme	/hyaluronic	817:827	arg1	acid					829:832	sodium alginate (SA)/hyaluronic acid	797:832	sodium alginate (SA)/hyaluronic acid (HA)	797:837	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	5	64	theme	nanohybrid	1123:1132	arg1	gels					1134:1137	the nanohybrid gels	1119:1137	the nanohybrid gels	1119:1137	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	2	65	theme	O2	543:544	arg1	glutathione					512:522	glutathione	512:522	glutathione (GSH)	512:528	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	65	theme	O2	543:544	arg1	GSH					525:527	GSH	525:527	GSH	525:527	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	65	theme	O2	543:544	arg1	H2O2					502:505	H2O2	502:505	H2O2	502:505	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	65	theme	O2	543:544	arg1	existence					480:488	the excessive existence	466:488	the excessive existence of H+ ions	466:499	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	65	theme	O2	543:544	arg1	lack					535:538	the lack	531:538	the lack of O2	531:544	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	65	theme	O2	543:544	arg1	relaxation					555:564	the relaxation	551:564	the relaxation of ferroptosis	551:579	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	7	66	theme	cuproptosis-enhanced	1667:1686	arg1	PTT/PDT/CDT					1688:1698	cuproptosis-enhanced PTT/PDT/CDT	1667:1698	cuproptosis-enhanced PTT/PDT/CDT	1667:1698	Hence, the novel design in our work provides another research avenue for cuproptosis-enhanced PTT/PDT/CDT via TME modulation.					
36933468	2	67	theme	tumor	369:373	arg1	microenvironment					375:390	the complex tumor microenvironment	357:390	the complex tumor microenvironment (TME)	357:396	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	67	theme	tumor	369:373	arg1	TME					393:395	TME	393:395	TME	393:395	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	3	68	theme	acid	829:832	arg1	nanoclusters					729:740	gold nanoclusters	724:740	gold nanoclusters	724:740	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	68	theme	acid	829:832	arg1	gel					790:792	an in situ cross-linking composite gel	755:792	an in situ cross-linking composite gel	755:792	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	68	theme	acid	829:832	arg1	cores					745:749	cores	745:749	cores	745:749	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	69	theme	composite	780:788	arg1	nanoclusters					729:740	gold nanoclusters	724:740	gold nanoclusters	724:740	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	69	theme	composite	780:788	arg1	gel					790:792	an in situ cross-linking composite gel	755:792	an in situ cross-linking composite gel	755:792	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	7	70	theme	novel	1605:1609	arg1	design					1611:1616	the novel design	1601:1616	the novel design in our work	1601:1628	Hence, the novel design in our work provides another research avenue for cuproptosis-enhanced PTT/PDT/CDT via TME modulation.					
36933468	6	71	theme	released	1346:1353	arg1	ions					1360:1363	the released Cu2+ ions	1342:1363	the released Cu2+ ions	1342:1363	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	2	72	theme	complex	361:367	arg1	microenvironment					375:390	the complex tumor microenvironment	357:390	the complex tumor microenvironment (TME)	357:396	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	2	72	theme	complex	361:367	arg1	TME					393:395	TME	393:395	TME	393:395	However, the complex tumor microenvironment (TME) is becoming the key barrier to the therapeutic effect of MCT due to the excessive existence of H+ ions, H2O2, and glutathione (GSH), the lack of O2, and the relaxation of ferroptosis.					
36933468	3	73	theme	SA	814:815	arg1	HA					835:836	HA	835:836	HA	835:836	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	73	theme	SA	814:815	arg1	acid					829:832	sodium alginate (SA)/hyaluronic acid	797:832	sodium alginate (SA)/hyaluronic acid (HA)	797:837	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	5	74	theme	hypoxic	1288:1294	arg1	microenvironment					1296:1311	the hypoxic microenvironment	1284:1311	the hypoxic microenvironment	1284:1311	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	0	75	theme	acid	77:80	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	6	76	theme	excessive	1383:1391	arg1	GSH					1393:1395	the excessive GSH	1379:1395	the excessive GSH	1379:1395	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	77	theme	tumor	1494:1498	arg1	cells					1500:1504	tumor cells	1494:1504	tumor cells	1494:1504	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	6	78	theme	Cu2+	1355:1358	arg1	ions					1360:1363	the released Cu2+ ions	1342:1363	the released Cu2+ ions	1342:1363	Furthermore, the released Cu2+ ions could consume the excessive GSH to form Cu+ ions effectively, which caused the formation of hydroxyl free radicals (·OH) to kill tumor cells, synergistically realizing GSH consumption-enhanced PDT and chemodynamic therapy (CDT).					
36933468	1	79	theme	tumor	278:282	arg1	cells					284:288	tumor cells	278:288	tumor cells	278:288	Multimodal combined therapy (MCT) is an emerging avenue to eliminate tumor cells by the synergistic effect of various therapeutic methods.					
36933468	0	80	theme	alginate/hyaluronic	57:75	arg1	gels					93:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels	23:96	novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis	23:112	In-situ fabrication of novel Au nanoclusters-Cu2+@sodium alginate/hyaluronic acid nanohybrid gels for cuproptosis enhanced photothermal/photodynamic/chemodynamic therapy via tumor microenvironment regulation.					
36933468	5	81	theme	H+-triggered	1080:1091	arg1	release					1093:1099	the H+-triggered release	1076:1099	the H+-triggered release of Cu2+ ions from the nanohybrid gels	1076:1137	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	5	81	theme	H+-triggered	1080:1091	arg1	Meanwhile					1065:1073	Meanwhile	1065:1073	Meanwhile	1065:1073	Meanwhile, the H+-triggered release of Cu2+ ions from the nanohybrid gels not only induces cuproptosis to avoid the relaxation of ferroptosis, but also catalyzes H2O2 in the TME to generate O2 to simultaneously improve the hypoxic microenvironment and PDT effect.					
36933468	4	82	contain	possessed	911:919	arg2	response					941:948	near-infrared light response	921:948	near-infrared light response	921:948	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	4	82	contain	possessed	911:919	arg1	gels					906:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels	853:909	The obtained Au NCs-Cu2+@SA-HA core-shell nanohybrid gels possessed near-infrared light response synergistically benefitting photothermal imaging guided photothermal therapy (PTT) and photodynamic therapy (PDT).					
36933468	3	83	theme	cross-linking	766:778	arg1	nanoclusters					729:740	gold nanoclusters	724:740	gold nanoclusters	724:740	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36933468	3	83	theme	cross-linking	766:778	arg1	gel					790:792	an in situ cross-linking composite gel	755:792	an in situ cross-linking composite gel	755:792	To overcome these limitations, smart nanohybrid gels with excellent biocompatibility, stability and targeting function were prepared by using gold nanoclusters as cores and an in situ cross-linking composite gel of sodium alginate (SA)/hyaluronic acid (HA) as the shell.					
36604065	4	0	theme	monofilaments	886:898	arg1	resistance					858:867	the permanent deformation resistance	832:867	the permanent deformation resistance of the composite monofilaments	832:898	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	1	theme	hot	745:747	arg1	stretching					749:758	multi-stage and high-ratio hot stretching	718:758	multi-stage and high-ratio hot stretching	718:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	2	theme	composite	876:884	arg1	monofilaments					886:898	the composite monofilaments	872:898	the composite monofilaments	872:898	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	2	3	theme	poly	351:354	arg1	monofilaments					423:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	0	4	theme	interfacial	95:105	arg1	bonding					107:113	interfacial bonding	95:113	interfacial bonding	95:113	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	4	5	theme	small	906:910	arg1	deformation					912:922	small deformation	906:922	small deformation	906:922	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	6	theme	permanent	836:844	arg1	resistance					858:867	the permanent deformation resistance	832:867	the permanent deformation resistance of the composite monofilaments	832:898	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	3	7	theme	amorphous	559:567	arg1	dispersion					586:595	amorphous PBS improved MCC dispersion	559:595	amorphous PBS improved MCC dispersion	559:595	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	8	theme	PBS	569:571	arg1	dispersion					586:595	amorphous PBS improved MCC dispersion	559:595	amorphous PBS improved MCC dispersion	559:595	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	5	9	theme	composite	992:1000	arg1	monofilaments					1002:1014	the composite monofilaments	988:1014	the composite monofilaments	988:1014	Moreover, the addition of MCC improved the biodegradability of the composite monofilaments after 60 days buried in soil.					
36604065	3	10	dep	PBS	481:483	arg1	deformation					493:503	plastic deformation	485:503	plastic deformation	485:503	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	10	dep	PBS	481:483	arg1	in-situ					513:519	plastic deformation and the in-situ	485:519	in-situ	513:519	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	11	theme	PBS	481:483	arg1	rigidity					459:466	rigidity	459:466	rigidity	459:466	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	11	theme	PBS	481:483	arg1	modulus					447:453	The high modulus	438:453	The high modulus	438:453	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	4	12	theme	10-25 wt	695:702	arg1	MCC					708:710	MCC	708:710	MCC after multi-stage and high-ratio hot stretching	708:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	12	theme	10-25 wt	695:702	arg1	%					703:703	10-25 wt%	695:703	10-25 wt% of MCC after multi-stage and high-ratio hot stretching	695:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	3	13	theme	plastic	485:491	arg1	deformation					493:503	plastic deformation	485:503	plastic deformation	485:503	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	2	14	theme	composite	413:421	arg1	monofilaments					423:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	3	15	theme	hydrogen	528:535	arg1	bonds					537:541	hydrogen bonds	528:541	hydrogen bonds between MCC and amorphous PBS improved MCC dispersion	528:595	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	4	16	theme	composite	666:674	arg1	monofilaments					676:688	The composite monofilaments	662:688	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching	662:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	1	17	theme	textile	177:183	arg1	fields					185:190	advanced textile fields	168:190	advanced textile fields	168:190	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
36604065	4	18	theme	deformation	846:856	arg1	resistance					858:867	the permanent deformation resistance	832:867	the permanent deformation resistance of the composite monofilaments	832:898	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	19	theme	double	769:774	arg1	behavior					785:792	a double yielding behavior	767:792	a double yielding behavior	767:792	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	6	20	theme	monofilaments	1120:1132	arg1	strategy					1085:1092	a design strategy	1076:1092	a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste	1076:1223	Therefore, our study provides a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste.					
36604065	2	21	theme	cellulose	393:401	arg1	monofilaments					423:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	4	22	with	monofilaments	676:688	arg1	MCC					708:710	MCC	708:710	MCC after multi-stage and high-ratio hot stretching	708:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	22	with	monofilaments	676:688	arg1	%					703:703	10-25 wt%	695:703	10-25 wt% of MCC after multi-stage and high-ratio hot stretching	695:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	6	23	theme	composite	1110:1118	arg1	monofilaments					1120:1132	microelastic composite monofilaments	1097:1132	microelastic composite monofilaments	1097:1132	Therefore, our study provides a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste.					
36604065	2	24	theme	melt	319:322	arg1	method					333:338	a solvent-free melt spinning method	304:338	a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	304:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	2	25	theme	/microcrystalline	375:391	arg1	monofilaments					423:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	2	26	theme	solvent-free	306:317	arg1	method					333:338	a solvent-free melt spinning method	304:338	a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	304:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	3	27	theme	MCC	471:473	arg1	PBS					481:483	MCC limit PBS plastic deformation and the in-situ	471:519	MCC limit PBS plastic deformation and the in-situ	471:519	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	5	28	theme	MCC	951:953	arg1	addition					939:946	the addition	935:946	the addition of MCC	935:953	Moreover, the addition of MCC improved the biodegradability of the composite monofilaments after 60 days buried in soil.					
36604065	6	29	theme	design	1078:1083	arg1	strategy					1085:1092	a design strategy	1076:1092	a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste	1076:1223	Therefore, our study provides a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste.					
36604065	0	30	theme	butylene	5:12	arg1	Poly					0:3	Poly	0:3	Poly(butylene succinate)	0:23	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	0	30	theme	butylene	5:12	arg1	succinate					14:22	butylene succinate	5:22	butylene succinate	5:22	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	4	31	theme	yielding	776:783	arg1	behavior					785:792	a double yielding behavior	767:792	a double yielding behavior	767:792	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	3	32	theme	physical	635:642	arg1	points					654:659	rigid MCC physical crosslink points	625:659	rigid MCC physical crosslink points	625:659	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	1	33	theme	advanced	168:175	arg1	fields					185:190	advanced textile fields	168:190	advanced textile fields	168:190	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
36604065	1	34	theme	practical	203:211	arg1	applications					213:224	their practical applications	197:224	their practical applications	197:224	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
36604065	3	35	theme	crosslink	644:652	arg1	points					654:659	rigid MCC physical crosslink points	625:659	rigid MCC physical crosslink points	625:659	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	36	theme	improved	573:580	arg1	dispersion					586:595	amorphous PBS improved MCC dispersion	559:595	amorphous PBS improved MCC dispersion	559:595	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	37	theme	high	442:445	arg1	modulus					447:453	The high modulus	438:453	The high modulus	438:453	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	38	theme	rigid	625:629	arg1	points					654:659	rigid MCC physical crosslink points	625:659	rigid MCC physical crosslink points	625:659	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	2	39	theme	PBS/MCC	404:410	arg1	monofilaments					423:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	3	40	theme	MCC	631:633	arg1	points					654:659	rigid MCC physical crosslink points	625:659	rigid MCC physical crosslink points	625:659	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	41	theme	MCC	582:584	arg1	dispersion					586:595	amorphous PBS improved MCC dispersion	559:595	amorphous PBS improved MCC dispersion	559:595	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	1	42	theme	Biodegradable	116:128	arg1	fibers					130:135	Biodegradable fibers	116:135	Biodegradable fibers	116:135	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
36604065	0	43	theme	composite	35:43	arg1	monofilaments					45:57	composite monofilaments	35:57	composite monofilaments with microelastic response based on interfacial bonding	35:113	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	4	44	theme	MCC	708:710	arg1	MCC					708:710	MCC	708:710	MCC after multi-stage and high-ratio hot stretching	708:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	4	44	theme	MCC	708:710	arg1	%					703:703	10-25 wt%	695:703	10-25 wt% of MCC after multi-stage and high-ratio hot stretching	695:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	3	45	theme	limit	475:479	arg1	PBS					481:483	MCC limit PBS plastic deformation and the in-situ	471:519	MCC limit PBS plastic deformation and the in-situ	471:519	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	3	46	theme	points	654:659	arg1	formation					612:620	the formation	608:620	the formation of rigid MCC physical crosslink points	608:659	The high modulus and rigidity of MCC limit PBS plastic deformation and the in-situ formed hydrogen bonds between MCC and amorphous PBS improved MCC dispersion and led to the formation of rigid MCC physical crosslink points.					
36604065	0	47	with	monofilaments	45:57	arg1	response					77:84	microelastic response	64:84	microelastic response based on interfacial bonding	64:113	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	2	48	theme	spinning	324:331	arg1	method					333:338	a solvent-free melt spinning method	304:338	a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	304:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	4	49	theme	multi-stage	718:728	arg1	stretching					749:758	multi-stage and high-ratio hot stretching	718:758	multi-stage and high-ratio hot stretching	718:758	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	0	50	theme	microelastic	64:75	arg1	response					77:84	microelastic response	64:84	microelastic response based on interfacial bonding	64:113	Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding.					
36604065	5	51	theme	monofilaments	1002:1014	arg1	biodegradability					968:983	the biodegradability	964:983	the biodegradability of the composite monofilaments	964:1014	Moreover, the addition of MCC improved the biodegradability of the composite monofilaments after 60 days buried in soil.					
36604065	6	52	theme	dimensional	1150:1160	arg1	stability					1162:1170	dimensional stability	1150:1170	dimensional stability	1150:1170	Therefore, our study provides a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste.					
36604065	6	53	theme	microelastic	1097:1108	arg1	monofilaments					1120:1132	microelastic composite monofilaments	1097:1132	microelastic composite monofilaments	1097:1132	Therefore, our study provides a design strategy of microelastic composite monofilaments for maintaining dimensional stability during use and accelerating degradation during waste.					
36604065	1	54	theme	large	241:245	arg1	deformation					255:265	large plastic deformation	241:265	large plastic deformation	241:265	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
36604065	4	55	theme	microelastic	798:809	arg1	response					811:818	microelastic response	798:818	microelastic response	798:818	The composite monofilaments with 10-25 wt% of MCC after multi-stage and high-ratio hot stretching showed a double yielding behavior and microelastic response, indicating the permanent deformation resistance of the composite monofilaments under small deformation.					
36604065	2	56	theme	butylene	356:363	arg1	poly					351:354	poly	351:354	poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments	351:435	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	2	56	theme	butylene	356:363	arg1	succinate					365:373	butylene succinate	356:373	butylene succinate	356:373	To solve this problem, we developed a solvent-free melt spinning method to prepare poly(butylene succinate)/microcrystalline cellulose (PBS/MCC) composite monofilaments.					
36604065	1	57	theme	plastic	247:253	arg1	deformation					255:265	large plastic deformation	241:265	large plastic deformation	241:265	Biodegradable fibers have been widely developed for advanced textile fields, but their practical applications are limited by large plastic deformation.					
35304178	8	0	theme	net	1408:1410	arg1	charge					1412:1417	the Mullikan net charge	1395:1417	the Mullikan net charge	1395:1417	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	7	1	theme	interface	1366:1374	arg1	coupling					1376:1383	the Fe-Cu interface coupling	1356:1383	the Fe-Cu interface coupling	1356:1383	In the meantime, the FCC electronic structure was modified due to the optimization of the Fe-Cu interface coupling.					
35304178	1	2	theme	antimony	109:116	arg1	contamination					123:135	alleviating antimony (Sb) contamination	97:135	alleviating antimony (Sb) contamination in aqueous solutions	97:156	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	7	3	theme	coupling	1376:1383	arg1	optimization					1340:1351	the optimization	1336:1351	the optimization of the Fe-Cu interface coupling	1336:1383	In the meantime, the FCC electronic structure was modified due to the optimization of the Fe-Cu interface coupling.					
35304178	4	4	theme	concentration	765:777	arg1	Sb					750:751	26.8 mg g-1 for Sb	734:751	26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1)	734:790	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	4	theme	concentration	765:777	arg1	5.0 mg L-1					780:789	initial concentration: 5.0 mg L-1	757:789	initial concentration: 5.0 mg L-1	757:789	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	0	5	theme	removal	40:46	arg1	mechanism					48:56	the Sb(III) and Sb(V) removal mechanism	18:56	the Sb(III) and Sb(V) removal mechanism	18:56	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.					
35304178	5	6	theme	major	1037:1041	arg1	contributor					1043:1053	a major contributor	1035:1053	a major contributor to adsorption enhancement	1035:1079	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	5	6	theme	major	1037:1041	arg1	coupling					1022:1029	Fe-Cu coupling	1016:1029	Fe-Cu coupling	1016:1029	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	6	7	theme	electrostatic	1128:1140	arg1	attraction					1142:1151	an electrostatic attraction	1125:1151	an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface	1125:1267	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	5	8	theme	Spectral	793:800	arg1	characterization					802:817	Spectral characterization	793:817	Spectral characterization	793:817	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	4	9	theme	2/1	610:612	arg1	34.5 mg g-1					706:716	34.5 mg g-1	706:716	34.5 mg g-1	706:716	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	9	theme	2/1	610:612	arg1	proportion					596:605	A Fe/Cu proportion	588:605	A Fe/Cu proportion of 2/1 (FCC-2/1)	588:622	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	9	theme	2/1	610:612	arg1	proportion					657:666	the optimum proportion	645:666	the optimum proportion for antimony adsorption	645:690	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	1	10	theme	environmental	213:225	arg1	health					227:232	environmental health	213:232	environmental health	213:232	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	5	11	theme	functional	850:859	arg1	simulations					874:884	density functional theory (DFT) simulations	842:884	density functional theory (DFT) simulations	842:884	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	5	12	theme	antimony	992:999	arg1	complexion					1001:1010	antimony complexion	992:1010	antimony complexion	992:1010	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	9	13	theme	Fe/Cu	1598:1602	arg1	3d					1604:1605	Fe/Cu 3d and O 2p orbital hybridization	1598:1636	3d	1604:1605	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	2	14	theme	efficient	314:322	arg1	imperative					366:375	imperative	366:375	imperative	366:375	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	2	14	theme	efficient	314:322	arg1	technique					324:332	an efficient technique	311:332	developing an efficient technique for antimony decontamination	300:361	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	3	15	theme	one-step	436:443	arg1	method					461:466	a one-step coprecipitation method	434:466	a one-step coprecipitation method	434:466	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	2	16	theme	developing	300:309	arg1	imperative					366:375	imperative	366:375	imperative	366:375	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	2	16	theme	developing	300:309	arg1	technique					324:332	an efficient technique	311:332	developing an efficient technique for antimony decontamination	300:361	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	3	17	theme	Fe-Cu-chitosan	400:413	arg1	composite					421:429	a Fe-Cu-chitosan (FCC) composite	398:429	a Fe-Cu-chitosan (FCC) composite	398:429	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	7	18	theme	Fe-Cu	1360:1364	arg1	coupling					1376:1383	the Fe-Cu interface coupling	1356:1383	the Fe-Cu interface coupling	1356:1383	In the meantime, the FCC electronic structure was modified due to the optimization of the Fe-Cu interface coupling.					
35304178	8	19	theme	Fe-O-Cu	1434:1440	arg1	bond					1442:1445	the intrinsic Fe-O-Cu bond	1420:1445	the intrinsic Fe-O-Cu bond	1420:1445	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	9	20	theme	O	1611:1611	arg1	hybridization					1624:1636	Fe/Cu 3d and O 2p orbital hybridization	1598:1636	hybridization	1624:1636	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	5	21	theme	Fe-Cu	1016:1020	arg1	contributor					1043:1053	a major contributor	1035:1053	a major contributor to adsorption enhancement	1035:1079	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	5	21	theme	Fe-Cu	1016:1020	arg1	coupling					1022:1029	Fe-Cu coupling	1016:1029	Fe-Cu coupling	1016:1029	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	4	22	theme	initial	757:763	arg1	Sb					750:751	26.8 mg g-1 for Sb	734:751	26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1)	734:790	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	22	theme	initial	757:763	arg1	5.0 mg L-1					780:789	initial concentration: 5.0 mg L-1	757:789	initial concentration: 5.0 mg L-1	757:789	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	23	theme	antimony	672:679	arg1	adsorption					681:690	antimony adsorption	672:690	antimony adsorption	672:690	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	8	24	theme	intrinsic	1424:1432	arg1	bond					1442:1445	the intrinsic Fe-O-Cu bond	1420:1445	the intrinsic Fe-O-Cu bond	1420:1445	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	0	25	theme	Deep	0:3	arg1	insight					5:11	Deep insight	0:11	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.	0:84	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.					
35304178	8	26	theme	interfacial	1459:1469	arg1	redistribution					1482:1495	interfacial electronic redistribution	1459:1495	interfacial electronic redistribution	1459:1495	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	4	27	theme	optimum	649:655	arg1	34.5 mg g-1					706:716	34.5 mg g-1	706:716	34.5 mg g-1	706:716	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	27	theme	optimum	649:655	arg1	proportion					596:605	A Fe/Cu proportion	588:605	A Fe/Cu proportion of 2/1 (FCC-2/1)	588:622	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	27	theme	optimum	649:655	arg1	proportion					657:666	the optimum proportion	645:666	the optimum proportion for antimony adsorption	645:690	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	5	28	theme	theory	861:866	arg1	simulations					874:884	density functional theory (DFT) simulations	842:884	density functional theory (DFT) simulations	842:884	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	2	29	theme	antimony	338:345	arg1	decontamination					347:361	antimony decontamination	338:361	antimony decontamination	338:361	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	8	30	theme	Mullikan	1399:1406	arg1	charge					1412:1417	the Mullikan net charge	1395:1417	the Mullikan net charge	1395:1417	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	9	31	theme	orbital	1616:1622	arg1	hybridization					1624:1636	Fe/Cu 3d and O 2p orbital hybridization	1598:1636	hybridization	1624:1636	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	5	32	theme	density	842:848	arg1	simulations					874:884	density functional theory (DFT) simulations	842:884	density functional theory (DFT) simulations	842:884	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	3	33	theme	active	506:511	arg1	sites					513:517	the active sites	502:517	the active sites	502:517	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	33	theme	active	506:511	arg1	Fe/Cu					488:492	nanoscale Fe/Cu	478:492	nanoscale Fe/Cu	478:492	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	7	34	theme	electronic	1295:1304	arg1	structure					1306:1314	the FCC electronic structure	1287:1314	the FCC electronic structure	1287:1314	In the meantime, the FCC electronic structure was modified due to the optimization of the Fe-Cu interface coupling.					
35304178	1	35	theme	aqueous	140:146	arg1	solutions					148:156	aqueous solutions	140:156	aqueous solutions	140:156	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	0	36	theme	Fe-Cu-chitosan	61:74	arg1	material					76:83	Fe-Cu-chitosan material	61:83	Fe-Cu-chitosan material	61:83	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.					
35304178	5	37	theme	DFT	869:871	arg1	simulations					874:884	density functional theory (DFT) simulations	842:884	density functional theory (DFT) simulations	842:884	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	5	38	from	mechanism	927:935	arg1	responsible					976:986	responsible	976:986	responsible	976:986	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	8	39	theme	electronic	1471:1480	arg1	redistribution					1482:1495	interfacial electronic redistribution	1459:1495	interfacial electronic redistribution	1459:1495	Based on the Mullikan net charge, the intrinsic Fe-O-Cu bond might favor interfacial electronic redistribution.					
35304178	6	40	theme	material	1250:1257	arg1	interface					1259:1267	the material interface	1246:1267	the material interface	1246:1267	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	9	41	theme	2p	1613:1614	arg1	hybridization					1624:1636	Fe/Cu 3d and O 2p orbital hybridization	1598:1636	hybridization	1624:1636	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	4	42	theme	for	746:748	arg1	5.0 mg L-1					780:789	initial concentration: 5.0 mg L-1	757:789	initial concentration: 5.0 mg L-1	757:789	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	42	theme	for	746:748	arg1	V					753:753	V	753:753	V	753:753	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	42	theme	for	746:748	arg1	Sb					750:751	26.8 mg g-1 for Sb	734:751	26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1)	734:790	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	3	43	theme	FCC	416:418	arg1	composite					421:429	a Fe-Cu-chitosan (FCC) composite	398:429	a Fe-Cu-chitosan (FCC) composite	398:429	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	0	44	theme	Sb	22:23	arg1	mechanism					48:56	the Sb(III) and Sb(V) removal mechanism	18:56	the Sb(III) and Sb(V) removal mechanism	18:56	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.					
35304178	4	45	theme	26.8 mg g-1	734:744	arg1	5.0 mg L-1					780:789	initial concentration: 5.0 mg L-1	757:789	initial concentration: 5.0 mg L-1	757:789	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	45	theme	26.8 mg g-1	734:744	arg1	V					753:753	V	753:753	V	753:753	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	45	theme	26.8 mg g-1	734:744	arg1	Sb					750:751	26.8 mg g-1 for Sb	734:751	26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1)	734:790	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	7	46	theme	FCC	1291:1293	arg1	structure					1306:1314	the FCC electronic structure	1287:1314	the FCC electronic structure	1287:1314	In the meantime, the FCC electronic structure was modified due to the optimization of the Fe-Cu interface coupling.					
35304178	4	47	theme	Fe/Cu	590:594	arg1	34.5 mg g-1					706:716	34.5 mg g-1	706:716	34.5 mg g-1	706:716	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	47	theme	Fe/Cu	590:594	arg1	proportion					596:605	A Fe/Cu proportion	588:605	A Fe/Cu proportion of 2/1 (FCC-2/1)	588:622	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	47	theme	Fe/Cu	590:594	arg1	proportion					657:666	the optimum proportion	645:666	the optimum proportion for antimony adsorption	645:690	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	5	48	from	responsible	976:986	arg1	mechanism					927:935	the adsorption mechanism	912:935	the adsorption mechanism	912:935	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	10	49	theme	mechanism	1771:1779	arg1	analysis					1781:1788	its adsorption mechanism analysis	1756:1788	its adsorption mechanism analysis	1756:1788	This work may offer a new perspective for binary oxide construction and its adsorption mechanism analysis.					
35304178	3	50	theme	whole	527:531	arg1	structure					533:541	the whole structure	523:541	the whole structure	523:541	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	50	theme	whole	527:531	arg1	particles					577:585	porous microscale particles	559:585	porous microscale particles	559:585	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	51	theme	coprecipitation	445:459	arg1	method					461:466	a one-step coprecipitation method	434:466	a one-step coprecipitation method	434:466	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	5	52	theme	adsorption	1058:1067	arg1	enhancement					1069:1079	adsorption enhancement	1058:1079	adsorption enhancement	1058:1079	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	6	53	theme	molecules	1233:1241	arg1	transportation					1206:1219	the transportation	1202:1219	the transportation of antimony molecules to the material interface	1202:1267	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	5	54	theme	surface	947:953	arg1	-OH					966:968	-OH	966:968	-OH	966:968	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	5	54	theme	surface	947:953	arg1	hydroxyls					955:963	surface hydroxyls	947:963	surface hydroxyls (-OH)	947:969	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	1	55	theme	alleviating	97:107	arg1	Sb					119:120	Sb	119:120	Sb	119:120	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	1	55	theme	alleviating	97:107	arg1	antimony					109:116	alleviating antimony	97:116	alleviating antimony (Sb) contamination in aqueous solutions	97:156	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	5	56	theme	adsorption	916:925	arg1	mechanism					927:935	the adsorption mechanism	912:935	the adsorption mechanism	912:935	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	6	57	theme	antimony	1224:1231	arg1	molecules					1233:1241	antimony molecules	1224:1241	antimony molecules	1224:1241	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	10	58	theme	adsorption	1760:1769	arg1	analysis					1781:1788	its adsorption mechanism analysis	1756:1788	its adsorption mechanism analysis	1756:1788	This work may offer a new perspective for binary oxide construction and its adsorption mechanism analysis.					
35304178	3	59	theme	microscale	566:575	arg1	structure					533:541	the whole structure	523:541	the whole structure	523:541	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	59	theme	microscale	566:575	arg1	particles					577:585	porous microscale particles	559:585	porous microscale particles	559:585	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	6	60	theme	adsorption	1164:1173	arg1	process					1175:1181	the adsorption process	1160:1181	the adsorption process	1160:1181	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	9	61	theme	antimony	1507:1514	arg1	molecule					1516:1523	the antimony molecule	1503:1523	the antimony molecule	1503:1523	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	9	62	theme	stabilizing	1664:1674	arg1	effect					1676:1681	a stabilizing effect	1662:1681	a stabilizing effect	1662:1681	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35304178	5	63	theme	batch	820:824	arg1	experiments					826:836	batch experiments	820:836	batch experiments	820:836	Spectral characterization, batch experiments and density functional theory (DFT) simulations were applied to determine the adsorption mechanism, in which surface hydroxyls (-OH) were responsible for antimony complexion and Fe-Cu coupling was a major contributor to adsorption enhancement.					
35304178	6	64	theme	kinetic	1095:1101	arg1	analysis					1103:1110	kinetic analysis	1095:1110	kinetic analysis	1095:1110	According to kinetic analysis, Cu provided an electrostatic attraction during the adsorption process, which facilitated the transportation of antimony molecules to the material interface.					
35304178	1	65	from	contamination	123:135	arg1	solutions					148:156	aqueous solutions	140:156	aqueous solutions	140:156	Currently, alleviating antimony (Sb) contamination in aqueous solutions is crucial for restoring and recovering ecological and environmental health.					
35304178	2	66	theme	mobile	276:281	arg1	characteristics					283:297	mobile characteristics	276:297	mobile characteristics	276:297	Due to its toxicity, bioaccumulation and mobile characteristics, developing an efficient technique for antimony decontamination is imperative.					
35304178	10	67	theme	new	1706:1708	arg1	perspective					1710:1720	a new perspective	1704:1720	a new perspective for binary oxide construction and its adsorption mechanism analysis	1704:1788	This work may offer a new perspective for binary oxide construction and its adsorption mechanism analysis.					
35304178	0	68	theme	Sb	34:35	arg1	mechanism					48:56	the Sb(III) and Sb(V) removal mechanism	18:56	the Sb(III) and Sb(V) removal mechanism	18:56	Deep insight into the Sb(III) and Sb(V) removal mechanism by Fe-Cu-chitosan material.					
35304178	4	69	dep	34.5 mg g-1	706:716	arg1	34.5 mg g-1					706:716	34.5 mg g-1	706:716	34.5 mg g-1	706:716	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	69	dep	34.5 mg g-1	706:716	arg1	proportion					596:605	A Fe/Cu proportion	588:605	A Fe/Cu proportion of 2/1 (FCC-2/1)	588:622	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	4	69	dep	34.5 mg g-1	706:716	arg1	proportion					657:666	the optimum proportion	645:666	the optimum proportion for antimony adsorption	645:690	A Fe/Cu proportion of 2/1 (FCC-2/1) was determined to be the optimum proportion for antimony adsorption, specifically 34.5 mg g-1 for Sb(III) and 26.8 mg g-1 for Sb(V) (initial concentration: 5.0 mg L-1).					
35304178	10	70	theme	binary	1726:1731	arg1	construction					1739:1750	binary oxide construction	1726:1750	binary oxide construction	1726:1750	This work may offer a new perspective for binary oxide construction and its adsorption mechanism analysis.					
35304178	3	71	theme	porous	559:564	arg1	structure					533:541	the whole structure	523:541	the whole structure	523:541	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	71	theme	porous	559:564	arg1	particles					577:585	porous microscale particles	559:585	porous microscale particles	559:585	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	10	72	theme	oxide	1733:1737	arg1	construction					1739:1750	binary oxide construction	1726:1750	binary oxide construction	1726:1750	This work may offer a new perspective for binary oxide construction and its adsorption mechanism analysis.					
35304178	3	73	theme	nanoscale	478:486	arg1	sites					513:517	the active sites	502:517	the active sites	502:517	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	3	73	theme	nanoscale	478:486	arg1	Fe/Cu					488:492	nanoscale Fe/Cu	478:492	nanoscale Fe/Cu	478:492	Herein, we prepared a Fe-Cu-chitosan (FCC) composite by a one-step coprecipitation method, in which nanoscale Fe/Cu acts as the active sites and the whole structure is exhibited as porous microscale particles.					
35304178	9	74	theme	adsorption	1539:1548	arg1	interface					1550:1558	the adsorption interface	1535:1558	the adsorption interface	1535:1558	When the antimony molecule contacted the adsorption interface, the electrons transferred swiftly as Fe/Cu 3d and O 2p orbital hybridization occurred, thus inducing a stabilizing effect.					
35042046	0	0	theme	pH	77:78	arg1	sensing					80:86	pH sensing	77:86	pH sensing	77:86	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	0	1	with	wet-spinning	24:35	arg1	nanoparticles					59:71	gold nanoparticles	54:71	gold nanoparticles for pH sensing	54:86	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	2	2	theme	active	315:320	arg1	substrate					322:330	active substrate	315:330	active substrate	315:330	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	4	3	theme	4-MPY/Ca-ALG	716:727	arg1	fibers					729:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers achieved fast response to the pH changes between 1.00 and 13.00.					
35042046	3	4	theme	4-MPY/Ca-ALG	567:578	arg1	fibers					580:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	4	theme	4-MPY/Ca-ALG	567:578	arg1	fibers					553:558	the as-synthesized composite fibers	524:558	the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers)	524:586	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	4	5	theme	pH	766:767	arg1	changes					769:775	the pH changes	762:775	the pH changes between 1.00 and 13.00	762:798	The AuNPs@4-MPY/Ca-ALG fibers achieved fast response to the pH changes between 1.00 and 13.00.					
35042046	5	6	theme	health	906:911	arg1	monitoring					913:922	health monitoring	906:922	health monitoring involving pH variation	906:945	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	3	7	theme	structures	655:664	arg1	changes					635:641	the changes	631:641	the changes of chemical structures of 4-MPY	631:673	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	8	theme	4-MPY	669:673	arg1	structures					655:664	chemical structures	646:664	chemical structures of 4-MPY	646:673	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	2	9	theme	gold	254:257	arg1	nanoparticles					259:271	gold nanoparticles	254:271	gold nanoparticles (AuNPs)	254:279	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	9	theme	gold	254:257	arg1	AuNPs					274:278	AuNPs	274:278	AuNPs	274:278	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	10	theme	SERS	348:351	arg1	enhancement					353:363	distinct SERS enhancement	339:363	distinct SERS enhancement	339:363	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	11	theme	rhodamine	414:422	arg1	6G					424:425	rhodamine 6G	414:425	rhodamine 6G	414:425	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	3	12	theme	chemical	646:653	arg1	structures					655:664	chemical structures	646:664	chemical structures of 4-MPY	646:673	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	4	13	theme	AuNPs	710:714	arg1	fibers					729:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers achieved fast response to the pH changes between 1.00 and 13.00.					
35042046	5	14	contain	has	876:878	arg1	"					867:867	a wearable "wrist band"	845:867	a wearable "wrist band"	845:867	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	5	14	contain	has	876:878	arg2	applications					890:901	potential applications	880:901	potential applications	880:901	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	0	15	theme	active	5:10	arg1	fibers					12:17	active fibers	5:17	active fibers	5:17	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	0	16	from	wet-spinning	24:35	arg1	SERS					0:3	SERS	0:3	SERS	0:3	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	5	17	theme	wrist	857:861	arg1	"					867:867	a wearable "wrist band"	845:867	a wearable "wrist band"	845:867	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	1	18	theme	pH	169:170	arg1	sensing					172:178	pH sensing	169:178	pH sensing based on surface enhanced Raman scattering (SERS)	169:228	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	3	19	theme	pH	691:692	arg1	conditions					694:703	different pH conditions	681:703	different pH conditions	681:703	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	20	theme	SERS	611:614	arg1	spectra					616:622	pH dependent SERS spectra	598:622	pH dependent SERS spectra	598:622	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	21	theme	@	566:566	arg1	fibers					580:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	21	theme	@	566:566	arg1	fibers					553:558	the as-synthesized composite fibers	524:558	the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers)	524:586	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	2	22	theme	distinct	339:346	arg1	enhancement					353:363	distinct SERS enhancement	339:363	distinct SERS enhancement	339:363	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	1	23	theme	Functional	89:98	arg1	fibers					110:115	Functional composite fibers	89:115	Functional composite fibers	89:115	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	5	24	theme	pH	934:935	arg1	variation					937:945	pH variation	934:945	pH variation	934:945	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	2	25	theme	dyes	391:394	arg1	concentrations					373:386	low concentrations	369:386	low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet)	369:462	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	5	26	theme	band	863:866	arg1	"					867:867	a wearable "wrist band"	845:867	a wearable "wrist band"	845:867	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	4	27	theme	@	715:715	arg1	fibers					729:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers	706:734	The AuNPs@4-MPY/Ca-ALG fibers achieved fast response to the pH changes between 1.00 and 13.00.					
35042046	1	28	theme	composite	100:108	arg1	fibers					110:115	Functional composite fibers	89:115	Functional composite fibers	89:115	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	3	29	theme	different	681:689	arg1	conditions					694:703	different pH conditions	681:703	different pH conditions	681:703	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	30	theme	composite	543:551	arg1	fibers					580:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	30	theme	composite	543:551	arg1	fibers					553:558	the as-synthesized composite fibers	524:558	the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers)	524:586	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	5	31	theme	flexible	805:812	arg1	fibers					824:829	The flexible composite fibers	801:829	The flexible composite fibers	801:829	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	5	32	theme	potential	880:888	arg1	applications					890:901	potential applications	880:901	potential applications	880:901	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	1	33	theme	enhanced	197:204	arg1	SERS					224:227	SERS	224:227	SERS	224:227	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	1	33	theme	enhanced	197:204	arg1	scattering					212:221	enhanced Raman scattering	197:221	surface enhanced Raman scattering (SERS)	189:228	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	0	34	theme	gold	54:57	arg1	nanoparticles					59:71	gold nanoparticles	54:71	gold nanoparticles for pH sensing	54:86	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	2	35	dep	dyes	391:394	arg1	M					408:408	1.0 × 10-9 M	397:408	1.0 × 10-9 M for rhodamine 6G	397:425	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	35	dep	dyes	391:394	arg1	M					442:442	1.0 × 10-8 M	431:442	1.0 × 10-8 M	431:442	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	35	dep	dyes	391:394	arg1	dyes					391:394	dyes	391:394	dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet)	391:462	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	0	36	theme	alginate	40:47	arg1	wet-spinning					24:35	wet-spinning	24:35	wet-spinning of alginate with gold nanoparticles for pH sensing	24:86	SERS active fibers from wet-spinning of alginate with gold nanoparticles for pH sensing.					
35042046	2	37	with	solution	240:247	arg1	nanoparticles					259:271	gold nanoparticles	254:271	gold nanoparticles (AuNPs)	254:279	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	37	with	solution	240:247	arg1	AuNPs					274:278	AuNPs	274:278	AuNPs	274:278	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	3	38	theme	as-synthesized	528:541	arg1	fibers					580:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	38	theme	as-synthesized	528:541	arg1	fibers					553:558	the as-synthesized composite fibers	524:558	the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers)	524:586	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	39	theme	AuNPs	561:565	arg1	fibers					580:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	AuNPs@4-MPY/Ca-ALG fibers	561:585	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	39	theme	AuNPs	561:565	arg1	fibers					553:558	the as-synthesized composite fibers	524:558	the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers)	524:586	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	40	mod	modified	482:489	arg3	4-MPY					516:520	4-MPY	516:520	4-MPY	516:520	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	40	mod	modified	482:489	arg3	4-mercaptopyridine					496:513	4-mercaptopyridine	496:513	4-mercaptopyridine (4-MPY)	496:521	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	3	40	mod	modified	482:489	arg1	AuNPs					471:475	AuNPs	471:475	AuNPs	471:475	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	1	41	dep	surface	189:195	arg1	SERS					224:227	SERS	224:227	SERS	224:227	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	1	41	dep	surface	189:195	arg1	scattering					212:221	enhanced Raman scattering	197:221	surface enhanced Raman scattering (SERS)	189:228	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	5	42	theme	wearable	847:854	arg1	"					867:867	a wearable "wrist band"	845:867	a wearable "wrist band"	845:867	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	2	43	dep	acting	305:310	arg1	showed					332:337	showed	332:337	showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet)	332:462	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	1	44	theme	Raman	206:210	arg1	SERS					224:227	SERS	224:227	SERS	224:227	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	1	44	theme	Raman	206:210	arg1	scattering					212:221	enhanced Raman scattering	197:221	surface enhanced Raman scattering (SERS)	189:228	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	3	45	theme	dependent	601:609	arg1	spectra					616:622	pH dependent SERS spectra	598:622	pH dependent SERS spectra	598:622	After AuNPs were modified with 4-mercaptopyridine (4-MPY), the as-synthesized composite fibers (AuNPs@4-MPY/Ca-ALG fibers) displayed pH dependent SERS spectra due to the changes of chemical structures of 4-MPY under different pH conditions.					
35042046	2	46	theme	Alginate	231:238	arg1	solution					240:247	Alginate solution	231:247	Alginate solution with gold nanoparticles (AuNPs)	231:279	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	2	47	theme	low	369:371	arg1	concentrations					373:386	low concentrations	369:386	low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet)	369:462	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	4	48	theme	fast	745:748	arg1	response					750:757	fast response	745:757	fast response to the pH changes between 1.00 and 13.00	745:798	The AuNPs@4-MPY/Ca-ALG fibers achieved fast response to the pH changes between 1.00 and 13.00.					
35042046	5	49	theme	composite	814:822	arg1	fibers					824:829	The flexible composite fibers	801:829	The flexible composite fibers	801:829	The flexible composite fibers were woven to a wearable "wrist band", which has potential applications in health monitoring involving pH variation.					
35042046	2	50	theme	crystal	448:454	arg1	violet					456:461	crystal violet	448:461	crystal violet	448:461	Alginate solution with gold nanoparticles (AuNPs) was spun to fibers that acting as active substrate showed distinct SERS enhancement for low concentrations of dyes (1.0 × 10-9 M for rhodamine 6G and 1.0 × 10-8 M for crystal violet).					
35042046	1	51	used	used	160:163	arg2	fibers					110:115	Functional composite fibers	89:115	Functional composite fibers	89:115	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
35042046	1	52	theme	wet-spinning	136:147	arg1	method					149:154	a wet-spinning method	134:154	a wet-spinning method	134:154	Functional composite fibers were prepared by a wet-spinning method and used for pH sensing based on surface enhanced Raman scattering (SERS).					
36088008	5	0	from	cellulose	828:836	arg1	catalyst					855:862	the composite catalyst	841:862	the composite catalyst	841:862	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	2	1	from	nanotubes	401:409	arg1	aerogel					424:430	cellulose aerogel	414:430	cellulose aerogel	414:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	6	2	dep	structure	1117:1125	arg1	an					1104:1105	an	1104:1105	an	1104:1105	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	4	3	theme	outstanding	623:633	arg1	related					684:690	related	684:690	related	684:690	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	4	3	theme	outstanding	623:633	arg1	performance					635:645	The outstanding performance	619:645	The outstanding performance of the composite catalyst	619:671	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	4	4	theme	synergistic	699:709	arg1	effect					711:716	the synergistic effect	695:716	the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network	695:789	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	1	5	theme	low	253:255	arg1	utilization					257:267	their low utilization	247:267	their low utilization	247:267	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	5	6	theme	semi-coated	871:881	arg1	structure					890:898	a semi-coated porous structure	869:898	a semi-coated porous structure	869:898	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	6	7	theme	physicochemical	1131:1145	arg1	properties					1147:1156	physicochemical properties	1131:1156	physicochemical properties	1131:1156	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	4	8	theme	composite	654:662	arg1	catalyst					664:671	the composite catalyst	650:671	the composite catalyst	650:671	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	6	9	theme	composite	1081:1089	arg1	aerogel					1091:1097	novel composite aerogel	1075:1097	novel composite aerogel with an excellent structure and physicochemical properties for water treatment	1075:1176	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	4	10	theme	porous	776:781	arg1	network					783:789	porous network	776:789	porous network	776:789	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	2	11	theme	MOF-derived	382:392	arg1	nanotubes					401:409	bimetallic MOF-derived carbon nanotubes	371:409	bimetallic MOF-derived carbon nanotubes on cellulose aerogel	371:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	6	12	theme	novel	1075:1079	arg1	aerogel					1091:1097	novel composite aerogel	1075:1097	novel composite aerogel with an excellent structure and physicochemical properties for water treatment	1075:1176	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	6	13	theme	excellent	1107:1115	arg1	structure					1117:1125	excellent structure	1107:1125	excellent structure	1107:1125	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	3	14	theme	NCNT	527:530	arg1	system					539:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	5	15	theme	carbon	807:812	arg1	nanotubes					814:822	carbon nanotubes	807:822	carbon nanotubes	807:822	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	2	16	theme	cellulose	414:422	arg1	aerogel					424:430	cellulose aerogel	414:430	cellulose aerogel	414:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	6	17	theme	water	1162:1166	arg1	treatment					1168:1176	water treatment	1162:1176	water treatment	1162:1176	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	4	18	theme	network	783:789	arg1	effect					711:716	the synergistic effect	695:716	the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network	695:789	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	1	19	theme	Metal-organic	102:114	arg1	MOFs					128:131	MOFs	128:131	MOFs	128:131	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	1	19	theme	Metal-organic	102:114	arg1	frameworks					116:125	Metal-organic frameworks	102:125	Metal-organic frameworks (MOFs)	102:132	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	2	20	theme	@	354:354	arg1	aerogel					333:339	a composite aerogel	321:339	a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel	321:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	2	20	theme	@	354:354	arg1	CA					355:356	CoFe0.8@NCNT@CA	342:356	CoFe0.8@NCNT@CA	342:356	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	0	21	theme	@	42:42	arg1	aerogels					53:60	@cellulose aerogels	42:60	@cellulose aerogels for peroxymonosulfate (PMS) activation	42:99	Bimetal-organic framework-derived nanotube@cellulose aerogels for peroxymonosulfate (PMS) activation.					
36088008	1	22	theme	secondary	273:281	arg1	pollution					283:291	secondary pollution	273:291	secondary pollution	273:291	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	5	23	theme	abundant	975:982	arg1	sites					991:995	abundant active sites	975:995	abundant active sites while ensuring mass transfer	975:1024	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	3	24	theme	CoFe0.8	519:525	arg1	system					539:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	5	25	theme	nanotubes	954:962	arg1	adhesion					935:942	the adhesion	931:942	the adhesion of carbon nanotubes	931:962	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	2	26	theme	carbon	394:399	arg1	nanotubes					401:409	bimetallic MOF-derived carbon nanotubes	371:409	bimetallic MOF-derived carbon nanotubes on cellulose aerogel	371:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	3	27	theme	@	531:531	arg1	system					539:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	5	28	theme	porous	883:888	arg1	structure					890:898	a semi-coated porous structure	869:898	a semi-coated porous structure	869:898	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	5	29	theme	mass	1012:1015	arg1	transfer					1017:1024	mass transfer	1012:1024	mass transfer	1012:1024	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	3	30	theme	@	526:526	arg1	system					539:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	1	31	theme	derived	144:150	arg1	catalysts					159:167	their derived powder catalysts	138:167	their derived powder catalysts	138:167	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	5	32	theme	carbon	947:952	arg1	nanotubes					954:962	carbon nanotubes	947:962	carbon nanotubes	947:962	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	1	33	link	derived	144:150	arg1	catalysts					159:167	their derived powder catalysts	138:167	their derived powder catalysts	138:167	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	3	34	theme	TC	592:593	arg1	removal					595:601	TC removal	592:601	97.1 % TC removal	585:601	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	4	35	theme	N	759:759	arg1	structure					761:769	graphitic N structure	749:769	graphitic N structure	749:769	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	2	36	theme	bimetallic	371:380	arg1	nanotubes					401:409	bimetallic MOF-derived carbon nanotubes	371:409	bimetallic MOF-derived carbon nanotubes on cellulose aerogel	371:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	0	37	theme	cellulose	43:51	arg1	aerogels					53:60	@cellulose aerogels	42:60	@cellulose aerogels for peroxymonosulfate (PMS) activation	42:99	Bimetal-organic framework-derived nanotube@cellulose aerogels for peroxymonosulfate (PMS) activation.					
36088008	1	38	theme	water	296:300	arg1	treatment					302:310	water treatment	296:310	water treatment	296:310	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	4	39	theme	graphitic	749:757	arg1	structure					761:769	graphitic N structure	749:769	graphitic N structure	749:769	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	3	40	dep	rate	579:582	arg1	%					590:590	97.1 %	585:590	97.1 % TC removal	585:601	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	0	41	theme	peroxymonosulfate	66:82	arg1	activation					90:99	peroxymonosulfate (PMS) activation	66:99	peroxymonosulfate (PMS) activation	66:99	Bimetal-organic framework-derived nanotube@cellulose aerogels for peroxymonosulfate (PMS) activation.					
36088008	6	42	with	aerogel	1091:1097	arg1	structure					1117:1125	excellent structure	1107:1125	excellent structure	1107:1125	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	6	42	with	aerogel	1091:1097	arg1	properties					1147:1156	physicochemical properties	1131:1156	physicochemical properties	1131:1156	This study provides a strategy for synthesizing novel composite aerogel with an excellent structure and physicochemical properties for water treatment.					
36088008	3	43	theme	CA/PMS	532:537	arg1	system					539:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system	515:544	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	5	44	theme	composite	845:853	arg1	catalyst					855:862	the composite catalyst	841:862	the composite catalyst	841:862	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	5	45	theme	active	984:989	arg1	sites					991:995	abundant active sites	975:995	abundant active sites while ensuring mass transfer	975:1024	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	4	46	theme	structure	761:769	arg1	effect					711:716	the synergistic effect	695:716	the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network	695:789	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	2	47	theme	composite	323:331	arg1	aerogel					333:339	a composite aerogel	321:339	a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel	321:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	2	47	theme	composite	323:331	arg1	CA					355:356	CoFe0.8@NCNT@CA	342:356	CoFe0.8@NCNT@CA	342:356	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	4	48	theme	sites	742:746	arg1	effect					711:716	the synergistic effect	695:716	the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network	695:789	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	4	49	theme	catalytic	732:740	arg1	sites					742:746	bimetallic catalytic sites	721:746	bimetallic catalytic sites	721:746	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	3	50	theme	removal	571:577	arg1	rate					579:582	an excellent TC removal rate	555:582	an excellent TC removal rate (97.1 % TC removal within 20 min)	555:616	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	4	51	theme	catalyst	664:671	arg1	related					684:690	related	684:690	related	684:690	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	4	51	theme	catalyst	664:671	arg1	performance					635:645	The outstanding performance	619:645	The outstanding performance of the composite catalyst	619:671	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	4	52	theme	bimetallic	721:730	arg1	sites					742:746	bimetallic catalytic sites	721:746	bimetallic catalytic sites	721:746	The outstanding performance of the composite catalyst is closely related to the synergistic effect of bimetallic catalytic sites, graphitic N structure, and porous network.					
36088008	1	53	theme	powder	152:157	arg1	catalysts					159:167	their derived powder catalysts	138:167	their derived powder catalysts	138:167	Metal-organic frameworks (MOFs) and their derived powder catalysts are prone to agglomerate and difficult to recycle in water, thus resulting in their low utilization and secondary pollution in water treatment.					
36088008	0	54	theme	PMS	85:87	arg1	activation					90:99	peroxymonosulfate (PMS) activation	66:99	peroxymonosulfate (PMS) activation	66:99	Bimetal-organic framework-derived nanotube@cellulose aerogels for peroxymonosulfate (PMS) activation.					
36088008	2	55	link	MOF-derived	382:392	arg1	nanotubes					401:409	bimetallic MOF-derived carbon nanotubes	371:409	bimetallic MOF-derived carbon nanotubes on cellulose aerogel	371:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	3	56	theme	excellent	558:566	arg1	rate					579:582	an excellent TC removal rate	555:582	an excellent TC removal rate (97.1 % TC removal within 20 min)	555:616	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	5	57	from	nanotubes	814:822	arg1	catalyst					855:862	the composite catalyst	841:862	the composite catalyst	841:862	Interestingly, carbon nanotubes and cellulose in the composite catalyst form a semi-coated porous structure, which can effectively enhance the adhesion of carbon nanotubes and expose abundant active sites while ensuring mass transfer.					
36088008	2	58	theme	NCNT	350:353	arg1	aerogel					333:339	a composite aerogel	321:339	a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel	321:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	2	58	theme	NCNT	350:353	arg1	CA					355:356	CoFe0.8@NCNT@CA	342:356	CoFe0.8@NCNT@CA	342:356	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	3	59	dep	%	590:590	arg1	removal					595:601	TC removal	592:601	97.1 % TC removal	585:601	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	3	60	theme	TC	568:569	arg1	rate					579:582	an excellent TC removal rate	555:582	an excellent TC removal rate (97.1 % TC removal within 20 min)	555:616	The CoFe0.8@NCNT@CA/PMS system exhibits an excellent TC removal rate (97.1 % TC removal within 20 min).					
36088008	2	61	theme	@	349:349	arg1	aerogel					333:339	a composite aerogel	321:339	a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel	321:430	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36088008	2	61	theme	@	349:349	arg1	CA					355:356	CoFe0.8@NCNT@CA	342:356	CoFe0.8@NCNT@CA	342:356	Herein, a composite aerogel (CoFe0.8@NCNT@CA) loaded with bimetallic MOF-derived carbon nanotubes on cellulose aerogel was developed for activating peroxymonosulfate (PMS) to degrade tetracycline (TC).					
36342199	3	0	theme	fecal	497:501	arg1	Firmicutes					503:512	fecal Firmicutes	497:512	fecal Firmicutes	497:512	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	15	1	theme	first	2575:2579	arg1	lyase					2597:2601	the first chondroitin ABC lyase	2571:2601	the first chondroitin ABC lyase	2571:2601	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	7	2	located	present	1140:1146	arg2	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	2	located	present	1140:1146	arg1	supernatant					1177:1187	the culture supernatant	1165:1187	the culture supernatant	1165:1187	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	2	located	present	1140:1146	arg2	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	17	3	theme	medicinal	3013:3021	arg1	applications					3023:3034	industrial and medicinal applications	2998:3034	industrial and medicinal applications	2998:3034	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	13	4	theme	desired	2265:2271	arg1	lyases					2247:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	13	4	theme	desired	2265:2271	arg1	enzymes					2273:2279	highly desired enzymes	2258:2279	highly desired enzymes for the production of GAG oligosaccharides and as therapeutics	2258:2342	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	12	5	theme	driving	2106:2112	arg1	factors					2114:2120	the driving factors	2102:2120	the driving factors for the composition, modulation, and homeostasis of the human gut microbiota	2102:2197	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	12	6	theme	metabolism	2041:2050	arg1	IMPORTANCE					1996:2005	IMPORTANCE	1996:2005	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria	1996:2073	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	5	7	theme	dermatan	841:848	arg1	sulfate					850:856	dermatan sulfate	841:856	dermatan sulfate	841:856	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	8	8	theme	sequence	1197:1204	arg1	analysis					1206:1213	Genome sequence analysis	1190:1213	Genome sequence analysis	1190:1213	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	10	9	theme	hydrolytic	1630:1639	arg1	product					1641:1647	the primary hydrolytic product	1618:1647	the primary hydrolytic product	1618:1647	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	5	10	dep	H.	759:760	arg1	hathewayi					762:770	H. hathewayi	759:770	H. hathewayi N2-326	759:777	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	8	11	theme	ABC	1279:1281	arg1	lyase					1283:1287	only the HH-chondroitin ABC lyase	1255:1287	only the HH-chondroitin ABC lyase	1255:1287	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	11	12	theme	commercial	1856:1865	arg1	option					1867:1872	a viable commercial option	1847:1872	a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications	1847:1993	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	7	13	theme	lyase	1086:1090	arg1	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	13	theme	lyase	1086:1090	arg1	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	3	14	theme	Hungatella	554:563	arg1	genomes					534:540	their genomes	528:540	their genomes	528:540	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	3	14	theme	Hungatella	554:563	arg1	strains					575:581	Hungatella hathewayi strains	554:581	Hungatella hathewayi strains	554:581	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	8	15	theme	putative	1230:1237	arg1	lyases					1243:1248	three putative GAG lyases	1224:1248	three putative GAG lyases	1224:1248	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	11	16	theme	medical	1974:1980	arg1	applications					1982:1993	potential medical applications	1964:1993	potential medical applications	1964:1993	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	11	17	theme	chondroitin	1896:1906	arg1	production					1882:1891	the production	1878:1891	the production of chondroitin, dermatan, and hyaluronan oligosaccharides	1878:1949	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	1	18	from	colonization	264:275	arg1	gut					290:292	the human gut	280:292	the human gut	280:292	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	13	19	theme	GAG-depolymerizing	2213:2230	arg1	lyases					2247:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	13	19	theme	GAG-depolymerizing	2213:2230	arg1	enzymes					2273:2279	highly desired enzymes	2258:2279	highly desired enzymes for the production of GAG oligosaccharides and as therapeutics	2258:2342	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	3	20	theme	abundant	591:598	arg1	genomes					534:540	their genomes	528:540	their genomes	528:540	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	3	20	theme	abundant	591:598	arg1	source					600:605	an abundant source	588:605	an abundant source of putative GAG-specific catabolic enzymes	588:648	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	1	21	theme	intestinal	222:231	arg1	bacteria					233:240	intestinal bacteria	222:240	intestinal bacteria	222:240	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	12	22	dep	IMPORTANCE	1996:2005	arg1	understanding					2020:2032	An increased understanding	2007:2032	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria	1996:2073	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	0	23	theme	Substrate	151:159	arg1	Specificity					161:171	Broad Substrate Specificity	145:171	Broad Substrate Specificity	145:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	15	24	theme	chondroitin	2581:2591	arg1	lyase					2597:2601	the first chondroitin ABC lyase	2571:2601	the first chondroitin ABC lyase	2571:2601	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	5	25	theme	GAG	912:914	arg1	degrader					916:923	a well-characterized GAG degrader	891:923	a well-characterized GAG degrader	891:923	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	5	25	theme	GAG	912:914	arg1	thetaiotaomicron					873:888	Bacteroides thetaiotaomicron	861:888	Bacteroides thetaiotaomicron	861:888	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	12	26	theme	human	2178:2182	arg1	microbiota					2188:2197	the human gut microbiota	2174:2197	the human gut microbiota	2174:2197	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	11	27	theme	intestinal	1814:1823	arg1	Firmicutes					1825:1834	intestinal Firmicutes	1814:1834	intestinal Firmicutes	1814:1834	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	3	28	theme	GAG-specific	619:630	arg1	enzymes					642:648	putative GAG-specific catabolic enzymes	610:648	putative GAG-specific catabolic enzymes	610:648	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	17	29	theme	chondroitin	2912:2922	arg1	lyase					2928:2932	the characterized chondroitin ABC lyase	2894:2932	the characterized chondroitin ABC lyase	2894:2932	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	17	30	theme	specific	2873:2880	arg1	activity					2882:2889	The high specific activity	2864:2889	The high specific activity of the characterized chondroitin ABC lyase aids future	2864:2944	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	8	31	theme	CSA	1324:1326	arg1	presence					1312:1319	the presence	1308:1319	the presence of CSA	1308:1326	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	0	32	theme	Human	79:83	arg1	Gut					85:87	Human Gut	79:87	Human Gut	79:87	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	15	33	theme	human	2541:2545	arg1	feces					2547:2551	human feces	2541:2551	human feces	2541:2551	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	5	34	theme	sulfate	821:827	arg1	CSA					832:834	CSA	832:834	CSA	832:834	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	5	34	theme	sulfate	821:827	arg1	A					829:829	chondroitin sulfate A	809:829	chondroitin sulfate A (CSA)	809:835	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	17	35	theme	lyase	2928:2932	arg1	activity					2882:2889	The high specific activity	2864:2889	The high specific activity of the characterized chondroitin ABC lyase aids future	2864:2944	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	7	36	from	present	1140:1146	arg1	supernatant					1177:1187	the culture supernatant	1165:1187	the culture supernatant	1165:1187	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	15	37	theme	fundamental	2644:2654	arg1	knowledge					2656:2664	the fundamental knowledge	2640:2664	the fundamental knowledge of GAG utilization in the human colon	2640:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	6	38	theme	B.	1002:1003	arg1	thetaiotaomicron					1005:1020	B. thetaiotaomicron	1002:1020	B. thetaiotaomicron	1002:1020	Unlike B. thetaiotaomicron, H. hathewayi N2-326 could not utilize heparin.					
36342199	17	39	theme	future	2939:2944	arg1	activity					2882:2889	The high specific activity	2864:2889	The high specific activity of the characterized chondroitin ABC lyase aids future	2864:2944	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	0	40	theme	Chondroitin	97:107	arg1	Hungatella					0:9	Hungatella	0:9	Hungatella	0:9	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	40	theme	Chondroitin	97:107	arg1	Exolyase					113:120	Its Chondroitin ABC Exolyase	93:120	Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity	93:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	15	41	theme	GAG-degrading	2501:2513	arg1	bacterium					2526:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	12	42	theme	increased	2010:2018	arg1	understanding					2020:2032	An increased understanding	2007:2032	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria	1996:2073	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	10	43	theme	HH-chondroitin	1494:1507	arg1	lyase					1513:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	15	44	from	utilization	2673:2683	arg1	colon					2698:2702	the human colon	2688:2702	the human colon	2688:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	14	45	theme	enzymatic	2379:2387	arg1	machinery					2389:2397	the enzymatic machinery	2375:2397	the enzymatic machinery for GAG degradation	2375:2417	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	10	46	theme	reported	1698:1705	arg1	lyases					1723:1728	reported chondroitin ABC lyases	1698:1728	reported chondroitin ABC lyases	1698:1728	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	11	47	theme	potential	1964:1972	arg1	applications					1982:1993	potential medical applications	1964:1993	potential medical applications	1964:1993	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	1	48	theme	human	284:288	arg1	gut					290:292	the human gut	280:292	the human gut	280:292	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	16	49	theme	distinct	2796:2803	arg1	approach					2805:2812	a distinct approach	2794:2812	a distinct approach	2794:2812	The genomic and transcriptomic analysis of the bacterium shows that Firmicutes might use a distinct approach to catabolize GAGs from that used by Bacteroides.					
36342199	17	50	theme	high	2868:2871	arg1	activity					2882:2889	The high specific activity	2864:2889	The high specific activity of the characterized chondroitin ABC lyase aids future	2864:2944	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	15	51	from	colon	2698:2702	arg1	knowledge					2656:2664	the fundamental knowledge	2640:2664	the fundamental knowledge of GAG utilization in the human colon	2640:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	7	52	theme	culture	1169:1175	arg1	supernatant					1177:1187	the culture supernatant	1165:1187	the culture supernatant	1165:1187	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	14	53	from	present	2348:2354	arg1	skewed					2429:2434	skewed	2429:2434	skewed	2429:2434	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	14	53	from	present	2348:2354	arg1	dissection					2361:2370	the dissection	2357:2370	the dissection of the enzymatic machinery for GAG degradation	2357:2417	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	10	54	theme	lyase	1513:1517	arg1	characterization					1458:1473	Further characterization	1450:1473	Further characterization of the recombinant HH-chondroitin ABC lyase	1450:1517	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	10	55	theme	ABC	1719:1721	arg1	lyases					1723:1728	reported chondroitin ABC lyases	1698:1728	reported chondroitin ABC lyases	1698:1728	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	0	56	theme	Efficient	25:33	arg1	Hungatella					0:9	Hungatella	0:9	Hungatella	0:9	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	56	theme	Efficient	25:33	arg1	Firmicutes					63:72	an Efficient Glycosaminoglycan-Degrading Firmicutes	22:72	an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut	22:87	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	9	57	theme	gene	1354:1357	arg1	clusters					1359:1366	five CAZyme gene clusters	1342:1366	five CAZyme gene clusters containing GAG metabolism genes	1342:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	0	58	with	Firmicutes	63:72	arg1	Specificity					161:171	Broad Substrate Specificity	145:171	Broad Substrate Specificity	145:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	58	with	Firmicutes	63:72	arg1	Activity					132:139	High Activity	127:139	High Activity	127:139	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	12	59	dep	composition	2130:2140	arg1	the					2126:2128	the	2126:2128	the	2126:2128	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	3	60	theme	enzymes	642:648	arg1	genomes					534:540	their genomes	528:540	their genomes	528:540	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	3	60	theme	enzymes	642:648	arg1	source					600:605	an abundant source	588:605	an abundant source of putative GAG-specific catabolic enzymes	588:648	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	3	61	theme	bioinformatic	471:483	arg1	analyses					485:492	Our bioinformatic analyses	467:492	Our bioinformatic analyses of fecal Firmicutes	467:512	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	13	62	theme	oligosaccharides	2307:2322	arg1	production					2289:2298	the production	2285:2298	the production of GAG oligosaccharides	2285:2322	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	11	63	theme	HH-chondroitin	1731:1744	arg1	lyase					1750:1754	HH-chondroitin ABC lyase	1731:1754	HH-chondroitin ABC lyase	1731:1754	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	13	64	from	enzymes	2273:2279	arg1	addition					2203:2210	addition	2203:2210	addition	2203:2210	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	11	65	theme	chondroitin	1791:1801	arg1	lyase					1803:1807	the first characterized chondroitin lyase	1767:1807	the first characterized chondroitin lyase from intestinal Firmicutes	1767:1834	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	11	66	theme	dermatan	1909:1916	arg1	production					1882:1891	the production	1878:1891	the production of chondroitin, dermatan, and hyaluronan oligosaccharides	1878:1949	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	9	67	theme	metabolism	1383:1392	arg1	genes					1394:1398	GAG metabolism genes	1379:1398	GAG metabolism genes	1379:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	7	68	theme	N2-326	1117:1122	arg1	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	68	theme	N2-326	1117:1122	arg1	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	9	69	contain	containing	1368:1377	arg1	clusters					1359:1366	five CAZyme gene clusters	1342:1366	five CAZyme gene clusters containing GAG metabolism genes	1342:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	9	69	contain	containing	1368:1377	arg2	genes					1394:1398	GAG metabolism genes	1379:1398	GAG metabolism genes	1379:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	3	70	theme	Firmicutes	503:512	arg1	analyses					485:492	Our bioinformatic analyses	467:492	Our bioinformatic analyses of fecal Firmicutes	467:512	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	15	71	theme	human	2692:2696	arg1	colon					2698:2702	the human colon	2688:2702	the human colon	2688:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	12	72	theme	GAG	2037:2039	arg1	metabolism					2041:2050	GAG metabolism	2037:2050	GAG metabolism	2037:2050	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	11	73	theme	oligosaccharides	1934:1949	arg1	production					1882:1891	the production	1878:1891	the production of chondroitin, dermatan, and hyaluronan oligosaccharides	1878:1949	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	11	74	theme	ABC	1746:1748	arg1	lyase					1750:1754	HH-chondroitin ABC lyase	1731:1754	HH-chondroitin ABC lyase	1731:1754	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	1	75	from	health	302:307	arg1	gut					290:292	the human gut	280:292	the human gut	280:292	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	15	76	theme	GAG	2669:2671	arg1	utilization					2673:2683	GAG utilization	2669:2683	GAG utilization in the human colon	2669:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	10	77	theme	unsaturated	1589:1599	arg1	disaccharides					1601:1613	unsaturated disaccharides	1589:1613	unsaturated disaccharides as the primary hydrolytic product	1589:1647	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	7	78	theme	H.	1104:1105	arg1	N2-326					1117:1122	H. hathewayi N2-326	1104:1122	H. hathewayi N2-326	1104:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	17	79	theme	characterized	2898:2910	arg1	lyase					2928:2932	the characterized chondroitin ABC lyase	2894:2932	the characterized chondroitin ABC lyase	2894:2932	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	12	80	theme	intestinal	2055:2064	arg1	bacteria					2066:2073	intestinal bacteria	2055:2073	intestinal bacteria	2055:2073	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	0	81	with	Exolyase	113:120	arg1	Specificity					161:171	Broad Substrate Specificity	145:171	Broad Substrate Specificity	145:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	81	with	Exolyase	113:120	arg1	Activity					132:139	High Activity	127:139	High Activity	127:139	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	3	82	theme	hathewayi	565:573	arg1	genomes					534:540	their genomes	528:540	their genomes	528:540	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	3	82	theme	hathewayi	565:573	arg1	strains					575:581	Hungatella hathewayi strains	554:581	Hungatella hathewayi strains	554:581	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	1	83	theme	glycosaminoglycans	193:210	arg1	critical					245:252	critical	245:252	critical	245:252	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	1	83	theme	glycosaminoglycans	193:210	arg1	degradation					178:188	The degradation	174:188	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria	174:240	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	8	84	theme	Genome	1190:1195	arg1	analysis					1206:1213	Genome sequence analysis	1190:1213	Genome sequence analysis	1190:1213	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	16	85	theme	genomic	2709:2715	arg1	analysis					2736:2743	The genomic and transcriptomic analysis	2705:2743	The genomic and transcriptomic analysis of the bacterium	2705:2760	The genomic and transcriptomic analysis of the bacterium shows that Firmicutes might use a distinct approach to catabolize GAGs from that used by Bacteroides.					
36342199	10	86	theme	primary	1622:1628	arg1	product					1641:1647	the primary hydrolytic product	1618:1647	the primary hydrolytic product	1618:1647	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	7	87	theme	chondroitin	1074:1084	arg1	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	87	theme	chondroitin	1074:1084	arg1	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	16	88	theme	transcriptomic	2721:2734	arg1	analysis					2736:2743	The genomic and transcriptomic analysis	2705:2743	The genomic and transcriptomic analysis of the bacterium	2705:2760	The genomic and transcriptomic analysis of the bacterium shows that Firmicutes might use a distinct approach to catabolize GAGs from that used by Bacteroides.					
36342199	8	89	theme	HH-chondroitin	1264:1277	arg1	lyase					1283:1287	only the HH-chondroitin ABC lyase	1255:1287	only the HH-chondroitin ABC lyase	1255:1287	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	10	90	theme	higher	1668:1673	arg1	activity					1684:1691	a higher specific activity	1666:1691	a higher specific activity than reported chondroitin ABC lyases	1666:1728	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	2	91	theme	colonic	327:333	arg1	Bacteroides					335:345	colonic Bacteroides	327:345	colonic Bacteroides	327:345	Both colonic Bacteroides and Firmicutes have been reported to degrade GAGs; however, the enzymatic details of the latter remain largely unknown.					
36342199	0	92	theme	Broad	145:149	arg1	Specificity					161:171	Broad Substrate Specificity	145:171	Broad Substrate Specificity	145:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	93	from	Gut	85:87	arg1	Exolyase					113:120	Its Chondroitin ABC Exolyase	93:120	Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity	93:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	93	from	Gut	85:87	arg1	Hungatella					0:9	Hungatella	0:9	Hungatella	0:9	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	93	from	Gut	85:87	arg1	Firmicutes					63:72	an Efficient Glycosaminoglycan-Degrading Firmicutes	22:72	an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut	22:87	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	1	94	theme	host	316:319	arg1	colonization					264:275	their colonization	258:275	their colonization in the human gut	258:292	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	1	94	theme	host	316:319	arg1	health					302:307	the health	298:307	the health of the host	298:319	The degradation of glycosaminoglycans (GAGs) by intestinal bacteria is critical for their colonization in the human gut and the health of the host.					
36342199	13	95	theme	polysaccharide	2232:2245	arg1	lyases					2247:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	GAG-depolymerizing polysaccharide lyases	2213:2252	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	13	95	theme	polysaccharide	2232:2245	arg1	enzymes					2273:2279	highly desired enzymes	2258:2279	highly desired enzymes for the production of GAG oligosaccharides and as therapeutics	2258:2342	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	5	96	theme	well-characterized	893:910	arg1	degrader					916:923	a well-characterized GAG degrader	891:923	a well-characterized GAG degrader	891:923	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	5	96	theme	well-characterized	893:910	arg1	thetaiotaomicron					873:888	Bacteroides thetaiotaomicron	861:888	Bacteroides thetaiotaomicron	861:888	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	8	97	theme	GAG	1239:1241	arg1	lyases					1243:1248	three putative GAG lyases	1224:1248	three putative GAG lyases	1224:1248	Genome sequence analysis revealed three putative GAG lyases, but only the HH-chondroitin ABC lyase was upregulated in the presence of CSA.					
36342199	16	98	theme	bacterium	2752:2760	arg1	analysis					2736:2743	The genomic and transcriptomic analysis	2705:2743	The genomic and transcriptomic analysis of the bacterium	2705:2760	The genomic and transcriptomic analysis of the bacterium shows that Firmicutes might use a distinct approach to catabolize GAGs from that used by Bacteroides.					
36342199	3	99	theme	putative	610:617	arg1	enzymes					642:648	putative GAG-specific catabolic enzymes	610:648	putative GAG-specific catabolic enzymes	610:648	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	15	100	theme	ABC	2593:2595	arg1	lyase					2597:2601	the first chondroitin ABC lyase	2571:2601	the first chondroitin ABC lyase	2571:2601	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	11	101	from	Firmicutes	1825:1834	arg1	lyase					1803:1807	the first characterized chondroitin lyase	1767:1807	the first characterized chondroitin lyase from intestinal Firmicutes	1767:1834	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	17	102	theme	commercial	2968:2977	arg1	chondroitinase					2979:2992	a commercial chondroitinase	2966:2992	a commercial chondroitinase for industrial and medicinal applications	2966:3034	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	12	103	theme	microbiota	2188:2197	arg1	modulation					2143:2152	modulation	2143:2152	modulation	2143:2152	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	12	103	theme	microbiota	2188:2197	arg1	homeostasis					2159:2169	homeostasis	2159:2169	homeostasis	2159:2169	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	12	103	theme	microbiota	2188:2197	arg1	composition					2130:2140	composition	2130:2140	composition	2130:2140	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	5	104	theme	Bacteroides	861:871	arg1	degrader					916:923	a well-characterized GAG degrader	891:923	a well-characterized GAG degrader	891:923	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	5	104	theme	Bacteroides	861:871	arg1	thetaiotaomicron					873:888	Bacteroides thetaiotaomicron	861:888	Bacteroides thetaiotaomicron	861:888	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	6	105	theme	H.	1023:1024	arg1	N2-326					1036:1041	H. hathewayi N2-326	1023:1041	H. hathewayi N2-326	1023:1041	Unlike B. thetaiotaomicron, H. hathewayi N2-326 could not utilize heparin.					
36342199	17	106	theme	ABC	2924:2926	arg1	lyase					2928:2932	the characterized chondroitin ABC lyase	2894:2932	the characterized chondroitin ABC lyase	2894:2932	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	4	107	theme	Firmicutes	679:688	arg1	H.					698:699	H.	698:699	H.	698:699	Subsequently, we isolated a Firmicutes strain, H. hathewayi N2-326, that can catabolize various GAGs.					
36342199	4	107	theme	Firmicutes	679:688	arg1	strain					690:695	a Firmicutes strain	677:695	a Firmicutes strain	677:695	Subsequently, we isolated a Firmicutes strain, H. hathewayi N2-326, that can catabolize various GAGs.					
36342199	5	108	theme	H.	759:760	arg1	N2-326					772:777	H. hathewayi N2-326	759:777	H. hathewayi N2-326	759:777	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	0	109	theme	High	127:130	arg1	Activity					132:139	High Activity	127:139	High Activity	127:139	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	10	110	theme	Further	1450:1456	arg1	characterization					1458:1473	Further characterization	1450:1473	Further characterization of the recombinant HH-chondroitin ABC lyase	1450:1517	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	15	111	from	knowledge	2656:2664	arg1	colon					2698:2702	the human colon	2688:2702	the human colon	2688:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	14	112	theme	GAG	2403:2405	arg1	degradation					2407:2417	GAG degradation	2403:2417	GAG degradation	2403:2417	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	11	113	theme	viable	1849:1854	arg1	option					1867:1872	a viable commercial option	1847:1872	a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications	1847:1993	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	0	114	theme	ABC	109:111	arg1	Hungatella					0:9	Hungatella	0:9	Hungatella	0:9	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	114	theme	ABC	109:111	arg1	Exolyase					113:120	Its Chondroitin ABC Exolyase	93:120	Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity	93:171	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	4	115	dep	H.	698:699	arg1	N2-326					711:716	N2-326	711:716	N2-326	711:716	Subsequently, we isolated a Firmicutes strain, H. hathewayi N2-326, that can catabolize various GAGs.					
36342199	4	115	dep	H.	698:699	arg1	hathewayi					701:709	H. hathewayi N2-326	698:716	H. hathewayi N2-326	698:716	Subsequently, we isolated a Firmicutes strain, H. hathewayi N2-326, that can catabolize various GAGs.					
36342199	7	116	attach	present	1140:1146	arg2	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	116	attach	present	1140:1146	arg1	supernatant					1177:1187	the culture supernatant	1165:1187	the culture supernatant	1165:1187	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	116	attach	present	1140:1146	arg2	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	14	117	theme	machinery	2389:2397	arg1	skewed					2429:2434	skewed	2429:2434	skewed	2429:2434	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	14	117	theme	machinery	2389:2397	arg1	dissection					2361:2370	the dissection	2357:2370	the dissection of the enzymatic machinery for GAG degradation	2357:2417	At present, the dissection of the enzymatic machinery for GAG degradation is highly skewed toward Bacteroides.					
36342199	15	118	theme	Firmicutes	2515:2524	arg1	bacterium					2526:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	12	119	theme	gut	2184:2186	arg1	microbiota					2188:2197	the human gut microbiota	2174:2197	the human gut microbiota	2174:2197	IMPORTANCE An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota.					
36342199	5	120	theme	hyaluronic	978:987	arg1	acid					989:992	hyaluronic acid	978:992	hyaluronic acid	978:992	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	7	121	from	supernatant	1177:1187	arg1	activity					1092:1099	The chondroitin lyase activity	1070:1099	The chondroitin lyase activity of H. hathewayi N2-326	1070:1122	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	7	121	from	supernatant	1177:1187	arg1	present					1140:1146	present	1140:1146	present	1140:1146	The chondroitin lyase activity of H. hathewayi N2-326 was found to be present predominantly in the culture supernatant.					
36342199	10	122	theme	recombinant	1482:1492	arg1	lyase					1513:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	15	123	theme	efficient	2491:2499	arg1	bacterium					2526:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	an efficient GAG-degrading Firmicutes bacterium	2488:2534	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36342199	10	124	theme	specific	1675:1682	arg1	activity					1684:1691	a higher specific activity	1666:1691	a higher specific activity than reported chondroitin ABC lyases	1666:1728	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	5	125	theme	chondroitin	809:819	arg1	sulfate					821:827	chondroitin sulfate	809:827	chondroitin sulfate A (CSA)	809:835	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	5	126	theme	B.	942:943	arg1	thetaiotaomicron					945:960	B. thetaiotaomicron	942:960	B. thetaiotaomicron in assimilating hyaluronic acid	942:992	While H. hathewayi N2-326 was as efficient in utilizing chondroitin sulfate A (CSA) and dermatan sulfate as Bacteroides thetaiotaomicron, a well-characterized GAG degrader, it outperformed B. thetaiotaomicron in assimilating hyaluronic acid.					
36342199	2	127	theme	enzymatic	411:419	arg1	details					421:427	the enzymatic details	407:427	the enzymatic details of the latter	407:441	Both colonic Bacteroides and Firmicutes have been reported to degrade GAGs; however, the enzymatic details of the latter remain largely unknown.					
36342199	4	128	theme	various	739:745	arg1	GAGs					747:750	various GAGs	739:750	various GAGs	739:750	Subsequently, we isolated a Firmicutes strain, H. hathewayi N2-326, that can catabolize various GAGs.					
36342199	17	129	theme	industrial	2998:3007	arg1	applications					3023:3034	industrial and medicinal applications	2998:3034	industrial and medicinal applications	2998:3034	The high specific activity of the characterized chondroitin ABC lyase aids future attempts to develop a commercial chondroitinase for industrial and medicinal applications.					
36342199	0	130	theme	Glycosaminoglycan-Degrading	35:61	arg1	Hungatella					0:9	Hungatella	0:9	Hungatella	0:9	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	0	130	theme	Glycosaminoglycan-Degrading	35:61	arg1	Firmicutes					63:72	an Efficient Glycosaminoglycan-Degrading Firmicutes	22:72	an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut	22:87	Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity.					
36342199	9	131	theme	CAZyme	1347:1352	arg1	clusters					1359:1366	five CAZyme gene clusters	1342:1366	five CAZyme gene clusters containing GAG metabolism genes	1342:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	10	132	theme	ABC	1509:1511	arg1	lyase					1513:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	the recombinant HH-chondroitin ABC lyase	1478:1517	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	3	133	theme	catabolic	632:640	arg1	enzymes					642:648	putative GAG-specific catabolic enzymes	610:648	putative GAG-specific catabolic enzymes	610:648	Our bioinformatic analyses of fecal Firmicutes revealed that their genomes, especially Hungatella hathewayi strains, are an abundant source of putative GAG-specific catabolic enzymes.					
36342199	10	134	theme	chondroitin	1707:1717	arg1	lyases					1723:1728	reported chondroitin ABC lyases	1698:1728	reported chondroitin ABC lyases	1698:1728	Further characterization of the recombinant HH-chondroitin ABC lyase revealed that it cleaves GAGs predominantly in an exo-mode to produce unsaturated disaccharides as the primary hydrolytic product while exhibiting a higher specific activity than reported chondroitin ABC lyases.					
36342199	13	135	theme	GAG	2303:2305	arg1	oligosaccharides					2307:2322	GAG oligosaccharides	2303:2322	GAG oligosaccharides	2303:2322	In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.					
36342199	2	136	theme	latter	436:441	arg1	details					421:427	the enzymatic details	407:427	the enzymatic details of the latter	407:441	Both colonic Bacteroides and Firmicutes have been reported to degrade GAGs; however, the enzymatic details of the latter remain largely unknown.					
36342199	11	137	theme	characterized	1777:1789	arg1	lyase					1803:1807	the first characterized chondroitin lyase	1767:1807	the first characterized chondroitin lyase from intestinal Firmicutes	1767:1834	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	11	138	theme	hyaluronan	1923:1932	arg1	oligosaccharides					1934:1949	hyaluronan oligosaccharides	1923:1949	hyaluronan oligosaccharides	1923:1949	HH-chondroitin ABC lyase represents the first characterized chondroitin lyase from intestinal Firmicutes and offers a viable commercial option for the production of chondroitin, dermatan, and hyaluronan oligosaccharides and also for potential medical applications.					
36342199	9	139	theme	GAG	1379:1381	arg1	genes					1394:1398	GAG metabolism genes	1379:1398	GAG metabolism genes	1379:1398	In addition, five CAZyme gene clusters containing GAG metabolism genes were significantly upregulated when grown on CSA.					
36342199	15	140	theme	utilization	2673:2683	arg1	knowledge					2656:2664	the fundamental knowledge	2640:2664	the fundamental knowledge of GAG utilization in the human colon	2640:2702	In this study, we have isolated an efficient GAG-degrading Firmicutes bacterium from human feces and characterized the first chondroitin ABC lyase from a Firmicutes, which complements the fundamental knowledge of GAG utilization in the human colon.					
36184186	3	0	theme	YPS-Pr-Li/BC/STA	490:505	arg1	film					507:510	the resulting YPS-Pr-Li/BC/STA film	476:510	the resulting YPS-Pr-Li/BC/STA film	476:510	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	7	1	contain	had	1018:1020	arg1	YPS-Pr-Li/BC/STA					1001:1016	YPS-Pr-Li/BC/STA	1001:1016	YPS-Pr-Li/BC/STA	1001:1016	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	7	1	contain	had	1018:1020	arg2	biocompatibility					1032:1047	excellent biocompatibility	1022:1047	excellent biocompatibility	1022:1047	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	6	2	theme	bacteriostatic	922:935	arg1	rate					937:940	a bacteriostatic rate	920:940	a bacteriostatic rate reaching 99 %	920:954	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	7	3	with	clothing	1090:1097	arg1	contact					1110:1116	close contact	1104:1116	close contact with human skin	1104:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	6	4	theme	bacteriostatic	837:850	arg1	performance					852:862	excellent bacteriostatic performance	827:862	excellent bacteriostatic performance against E. coli and S. aureus	827:892	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	5	5	theme	ultraviolet	719:729	arg1	luminescence					753:764	ultraviolet, visible upconversion luminescence	719:764	ultraviolet, visible upconversion luminescence	719:764	The results showed that the composite film was successfully prepared and had ultraviolet, visible upconversion luminescence.					
36184186	3	6	contain	had	512:514	arg1	film					507:510	the resulting YPS-Pr-Li/BC/STA film	476:510	the resulting YPS-Pr-Li/BC/STA film	476:510	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	3	6	contain	had	512:514	arg2	surface					540:546	an improved hydrophobic surface	516:546	an improved hydrophobic surface	516:546	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	6	7	theme	excellent	827:835	arg1	performance					852:862	excellent bacteriostatic performance	827:862	excellent bacteriostatic performance against E. coli and S. aureus	827:892	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	7	8	theme	in-vitro	961:968	arg1	tests					983:987	The in-vitro cytotoxicity tests	957:987	The in-vitro cytotoxicity tests	957:987	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	7	9	theme	cytotoxicity	970:981	arg1	tests					983:987	The in-vitro cytotoxicity tests	957:987	The in-vitro cytotoxicity tests	957:987	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	3	10	theme	improved	519:526	arg1	surface					540:546	an improved hydrophobic surface	516:546	an improved hydrophobic surface	516:546	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	3	11	theme	low	434:436	arg1	energy					446:451	the low surface energy	430:451	the low surface energy of stearic acid (STA)	430:473	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	5	12	theme	upconversion	740:751	arg1	luminescence					753:764	ultraviolet, visible upconversion luminescence	719:764	ultraviolet, visible upconversion luminescence	719:764	The results showed that the composite film was successfully prepared and had ultraviolet, visible upconversion luminescence.					
36184186	2	13	theme	composite	291:299	arg1	film					301:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	6	14	theme	visible	900:906	arg1	light					908:912	visible light	900:912	visible light	900:912	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	7	15	theme	protective	1079:1088	arg1	clothing					1090:1097	personal protective clothing	1070:1097	personal protective clothing with close contact with human skin	1070:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	2	16	theme	assisted	394:401	arg1	method					403:408	a vacuum assisted method	385:408	a vacuum assisted method	385:408	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	4	17	theme	developed	553:561	arg1	film					563:566	The developed film	549:566	The developed film	549:566	The developed film was characterized by FT-IR, SEM, XRD, and fluorescence spectrophotometry.					
36184186	7	18	theme	human	1123:1127	arg1	skin					1129:1132	human skin	1123:1132	human skin	1123:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	2	19	theme	upconversion	329:340	arg1	powder					342:347	upconversion powder	329:347	upconversion powder	329:347	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	3	20	theme	surface	438:444	arg1	energy					446:451	the low surface energy	430:451	the low surface energy of stearic acid (STA)	430:473	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	0	21	theme	hydrophobic	35:45	arg1	film					67:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	Vis-UV Upconverting bacteriostatic hydrophobic bacterial cellulose film for personal protective masks.					
36184186	7	22	theme	close	1104:1108	arg1	contact					1110:1116	close contact	1104:1116	close contact with human skin	1104:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	0	23	dep	protective	85:94	arg1	masks					96:100	masks	96:100	masks	96:100	Vis-UV Upconverting bacteriostatic hydrophobic bacterial cellulose film for personal protective masks.					
36184186	4	24	theme	fluorescence	610:621	arg1	spectrophotometry					623:639	fluorescence spectrophotometry	610:639	fluorescence spectrophotometry	610:639	The developed film was characterized by FT-IR, SEM, XRD, and fluorescence spectrophotometry.					
36184186	0	25	theme	bacteriostatic	20:33	arg1	film					67:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	Vis-UV Upconverting bacteriostatic hydrophobic bacterial cellulose film for personal protective masks.					
36184186	0	26	theme	cellulose	57:65	arg1	film					67:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	Vis-UV Upconverting bacteriostatic hydrophobic bacterial cellulose film for personal protective masks.					
36184186	2	27	theme	vacuum	387:392	arg1	method					403:408	a vacuum assisted method	385:408	a vacuum assisted method	385:408	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	3	28	theme	stearic	456:462	arg1	acid					464:467	stearic acid	456:467	stearic acid (STA)	456:473	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	3	28	theme	stearic	456:462	arg1	STA					470:472	STA	470:472	STA	470:472	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	0	29	theme	bacterial	47:55	arg1	film					67:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	bacteriostatic hydrophobic bacterial cellulose film	20:70	Vis-UV Upconverting bacteriostatic hydrophobic bacterial cellulose film for personal protective masks.					
36184186	7	30	used	used	1062:1065	arg2	YPS-Pr-Li/BC/STA					1001:1016	YPS-Pr-Li/BC/STA	1001:1016	YPS-Pr-Li/BC/STA	1001:1016	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	6	31	theme	bacteriostatic	771:784	arg1	experiments					786:796	The bacteriostatic experiments	767:796	The bacteriostatic experiments	767:796	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	3	32	theme	acid	464:467	arg1	energy					446:451	the low surface energy	430:451	the low surface energy of stearic acid (STA)	430:473	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	7	33	theme	personal	1070:1077	arg1	clothing					1090:1097	personal protective clothing	1070:1097	personal protective clothing with close contact with human skin	1070:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	1	34	theme	personal	120:127	arg1	protection					129:138	personal protection	120:138	personal protection	120:138	Masks are key to personal protection and their bacteriostatic properties, which are generally overlooked, should be maximized.					
36184186	5	35	theme	composite	670:678	arg1	film					680:683	the composite film	666:683	the composite film	666:683	The results showed that the composite film was successfully prepared and had ultraviolet, visible upconversion luminescence.					
36184186	3	36	theme	resulting	480:488	arg1	film					507:510	the resulting YPS-Pr-Li/BC/STA film	476:510	the resulting YPS-Pr-Li/BC/STA film	476:510	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	5	37	dep	ultraviolet	719:729	arg1	visible					732:738	visible	732:738	visible	732:738	The results showed that the composite film was successfully prepared and had ultraviolet, visible upconversion luminescence.					
36184186	2	38	theme	antibacterial	277:289	arg1	film					301:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	2	39	theme	bacterial	354:362	arg1	cellulose					364:372	bacterial cellulose	354:372	bacterial cellulose (BC) using a vacuum assisted method	354:408	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	2	39	theme	bacterial	354:362	arg1	BC					375:376	BC	375:376	BC	375:376	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	3	40	theme	hydrophobic	528:538	arg1	surface					540:546	an improved hydrophobic surface	516:546	an improved hydrophobic surface	516:546	When combined with the low surface energy of stearic acid (STA), the resulting YPS-Pr-Li/BC/STA film had an improved hydrophobic surface.					
36184186	2	41	theme	upconversion	264:275	arg1	film					301:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	7	42	with	contact	1110:1116	arg1	skin					1129:1132	human skin	1123:1132	human skin	1123:1132	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	2	43	theme	YPS-Pr-Li/BC	251:262	arg1	film					301:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	a YPS-Pr-Li/BC upconversion antibacterial composite film	249:304	Towards this goal, a YPS-Pr-Li/BC upconversion antibacterial composite film was prepared by mixing upconversion powder with bacterial cellulose (BC) using a vacuum assisted method.					
36184186	7	44	theme	excellent	1022:1030	arg1	biocompatibility					1032:1047	excellent biocompatibility	1022:1047	excellent biocompatibility	1022:1047	The in-vitro cytotoxicity tests showed that YPS-Pr-Li/BC/STA had excellent biocompatibility and could be used in personal protective clothing with close contact with human skin.					
36184186	1	45	theme	bacteriostatic	150:163	arg1	properties					165:174	their bacteriostatic properties	144:174	their bacteriostatic properties	144:174	Masks are key to personal protection and their bacteriostatic properties, which are generally overlooked, should be maximized.					
36184186	6	46	contain	had	823:825	arg2	performance					852:862	excellent bacteriostatic performance	827:862	excellent bacteriostatic performance against E. coli and S. aureus	827:892	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
36184186	6	46	contain	had	823:825	arg1	material					814:821	the material	810:821	the material	810:821	The bacteriostatic experiments showed that the material had excellent bacteriostatic performance against E. coli and S. aureus under visible light, with a bacteriostatic rate reaching 99 %.					
37179492	4	0	theme	refrigerator	598:609	arg1	temperature					611:621	refrigerator temperature	598:621	refrigerator temperature	598:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	4	1	theme	Poloxamer338	537:548	arg1	gels					565:568	low Poloxamer338 (P338) content gels	533:568	low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature	533:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	9	2	theme	adhesion	1295:1302	arg1	mechanism					1316:1324	Its adhesion suppression mechanism	1291:1324	Its adhesion suppression mechanism	1291:1324	Its adhesion suppression mechanism was verified, and it also displayed good biosafety.					
37179492	5	3	theme	composite	765:773	arg1	PCHgel					785:790	PCHgel	785:790	PCHgel	785:790	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	5	3	theme	composite	765:773	arg1	hydrogel					775:782	construct P338/CMCS-heparin composite hydrogel	737:782	construct P338/CMCS-heparin composite hydrogel (PCHgel)	737:791	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	4	4	theme	low	533:535	arg1	gels					565:568	low Poloxamer338 (P338) content gels	533:568	low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature	533:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	5	5	theme	effective	689:697	arg1	inhibitor					708:716	an effective adhesion inhibitor	686:716	an effective adhesion inhibitor	686:716	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	5	5	theme	effective	689:697	arg1	Heparin					677:683	Heparin	677:683	Heparin	677:683	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	2	6	theme	tissue	315:320	arg1	adhesion					322:329	tissue adhesion	315:329	tissue adhesion	315:329	Medical hydrogels could be applied at surgical sites as a physical barrier to prevent tissue adhesion.					
37179492	4	7	from	temperature	611:621	arg1	viscosity					585:593	low viscosity	581:593	low viscosity at refrigerator temperature	581:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	6	8	theme	damaged	910:916	arg1	tissue					918:923	damaged tissue	910:923	damaged tissue	910:923	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	5	9	theme	adhesion	699:706	arg1	inhibitor					708:716	an effective adhesion inhibitor	686:716	an effective adhesion inhibitor	686:716	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	5	9	theme	adhesion	699:706	arg1	Heparin					677:683	Heparin	677:683	Heparin	677:683	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	10	10	theme	transformation	1417:1430	arg1	potential					1432:1440	good clinical transformation potential	1403:1440	good clinical transformation potential	1403:1440	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	7	11	theme	CMCS	972:975	arg1	introduction					956:967	The introduction	952:967	The introduction of CMCS	952:975	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	9	12	theme	good	1362:1365	arg1	biosafety					1367:1375	good biosafety	1362:1375	good biosafety	1362:1375	Its adhesion suppression mechanism was verified, and it also displayed good biosafety.					
37179492	8	13	theme	tissue	1193:1198	arg1	adhesion					1200:1207	tissue adhesion	1193:1207	tissue adhesion	1193:1207	Ultimately, PCHgel significantly reduced tissue adhesion in model rats and displayed higher efficiency than P338/CMCS gel without heparin.					
37179492	6	14	theme	liquid	824:829	arg1	°C					840:841	a flowable liquid below 20 °C	813:841	a flowable liquid below 20 °C	813:841	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	10	15	dep	good	1403:1406	arg1	clinical					1408:1415	clinical	1408:1415	clinical	1408:1415	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	8	16	theme	P338/CMCS	1260:1268	arg1	gel					1270:1272	P338/CMCS gel	1260:1272	P338/CMCS gel	1260:1272	Ultimately, PCHgel significantly reduced tissue adhesion in model rats and displayed higher efficiency than P338/CMCS gel without heparin.					
37179492	0	17	theme	Temperature-Sensitive	11:31	arg1	Hydrogel					33:40	Degradable Temperature-Sensitive Hydrogel	0:40	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin	0:60	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin Effectively Prevents Post-Operative Tissue Adhesions.					
37179492	4	18	theme	poloxamer-based	495:509	arg1	hydrogels					511:519	poloxamer-based hydrogels	495:519	poloxamer-based hydrogels	495:519	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	7	19	theme	healing	1099:1105	arg1	period					1107:1112	the wound healing period	1089:1112	the wound healing period	1089:1112	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	6	20	theme	flowable	815:822	arg1	°C					840:841	a flowable liquid below 20 °C	813:841	a flowable liquid below 20 °C	813:841	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	1	21	theme	Tissue	116:121	arg1	adhesions					123:131	Tissue adhesions	116:131	Tissue adhesions	116:131	Tissue adhesions could occur following surgeries, and severe tissue adhesions can lead to serious complications.					
37179492	1	22	theme	serious	206:212	arg1	complications					214:226	serious complications	206:226	serious complications	206:226	Tissue adhesions could occur following surgeries, and severe tissue adhesions can lead to serious complications.					
37179492	0	23	theme	Degradable	0:9	arg1	Hydrogel					33:40	Degradable Temperature-Sensitive Hydrogel	0:40	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin	0:60	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin Effectively Prevents Post-Operative Tissue Adhesions.					
37179492	5	24	theme	construct	737:745	arg1	PCHgel					785:790	PCHgel	785:790	PCHgel	785:790	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	5	24	theme	construct	737:745	arg1	hydrogel					775:782	construct P338/CMCS-heparin composite hydrogel	737:782	construct P338/CMCS-heparin composite hydrogel (PCHgel)	737:791	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	10	25	theme	high	1447:1450	arg1	efficacy					1452:1459	high efficacy	1447:1459	high efficacy	1447:1459	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	7	26	theme	wound	1093:1097	arg1	healing					1099:1105	wound healing	1093:1105	the wound healing period	1089:1112	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	4	27	theme	body	659:662	arg1	temperature					664:674	body temperature	659:674	body temperature	659:674	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	8	28	theme	higher	1237:1242	arg1	efficiency					1244:1253	higher efficiency	1237:1253	higher efficiency than P338/CMCS gel	1237:1272	Ultimately, PCHgel significantly reduced tissue adhesion in model rats and displayed higher efficiency than P338/CMCS gel without heparin.					
37179492	4	29	theme	low	581:583	arg1	viscosity					585:593	low viscosity	581:593	low viscosity at refrigerator temperature	581:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	3	30	dep	spreadable	355:364	arg1	gels					397:400	gels	397:400	gels	397:400	For practical reasons, spreadable, degradable, and self-healable gels are highly demanded.					
37179492	4	31	theme	carboxymethyl	462:474	arg1	chitosan					476:483	carboxymethyl chitosan	462:483	carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels	462:519	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	4	31	theme	carboxymethyl	462:474	arg1	CMCS					486:489	CMCS	486:489	CMCS	486:489	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	2	32	theme	surgical	267:274	arg1	sites					276:280	surgical sites	267:280	surgical sites as a physical barrier to prevent tissue adhesion	267:329	Medical hydrogels could be applied at surgical sites as a physical barrier to prevent tissue adhesion.					
37179492	4	33	theme	P338	551:554	arg1	gels					565:568	low Poloxamer338 (P338) content gels	533:568	low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature	533:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	5	34	theme	P338/CMCS-heparin	747:763	arg1	PCHgel					785:790	PCHgel	785:790	PCHgel	785:790	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	5	34	theme	P338/CMCS-heparin	747:763	arg1	hydrogel					775:782	construct P338/CMCS-heparin composite hydrogel	737:782	construct P338/CMCS-heparin composite hydrogel (PCHgel)	737:791	Heparin, an effective adhesion inhibitor, was also added to construct P338/CMCS-heparin composite hydrogel (PCHgel).					
37179492	8	35	theme	model	1212:1216	arg1	rats					1218:1221	model rats	1212:1221	model rats	1212:1221	Ultimately, PCHgel significantly reduced tissue adhesion in model rats and displayed higher efficiency than P338/CMCS gel without heparin.					
37179492	7	36	theme	injured	1037:1043	arg1	positions					1045:1053	injured positions	1037:1053	injured positions	1037:1053	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	6	37	theme	tissue	918:923	arg1	surface					899:905	the surface	895:905	the surface of damaged tissue due to temperature change	895:949	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	4	38	theme	content	557:563	arg1	gels					565:568	low Poloxamer338 (P338) content gels	533:568	low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature	533:621	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	3	39	theme	practical	336:344	arg1	reasons					346:352	practical reasons	336:352	practical reasons	336:352	For practical reasons, spreadable, degradable, and self-healable gels are highly demanded.					
37179492	6	40	theme	due	925:927	arg1	surface					899:905	the surface	895:905	the surface of damaged tissue due to temperature change	895:949	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	7	41	theme	self-healable	1012:1024	arg1	barrier					1026:1032	a stable self-healable barrier	1003:1032	a stable self-healable barrier	1003:1032	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	10	42	theme	use	1487:1489	arg1	efficacy					1452:1459	high efficacy	1447:1459	high efficacy	1447:1459	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	10	42	theme	use	1487:1489	arg1	safety					1467:1472	good safety	1462:1472	good safety	1462:1472	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	10	42	theme	use	1487:1489	arg1	ease					1479:1482	ease	1479:1482	ease of use	1479:1489	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	10	43	theme	good	1462:1465	arg1	safety					1467:1472	good safety	1462:1472	good safety	1462:1472	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	2	44	theme	physical	287:294	arg1	barrier					296:302	a physical barrier	285:302	a physical barrier to prevent tissue adhesion	285:329	Medical hydrogels could be applied at surgical sites as a physical barrier to prevent tissue adhesion.					
37179492	4	45	theme	mechanical	636:645	arg1	strength					647:654	mechanical strength	636:654	mechanical strength	636:654	To meet these requirements, we applied carboxymethyl chitosan (CMCS) to poloxamer-based hydrogels to generate low Poloxamer338 (P338) content gels displaying low viscosity at refrigerator temperature and improved mechanical strength at body temperature.					
37179492	2	46	theme	Medical	229:235	arg1	hydrogels					237:245	Medical hydrogels	229:245	Medical hydrogels	229:245	Medical hydrogels could be applied at surgical sites as a physical barrier to prevent tissue adhesion.					
37179492	10	47	theme	good	1403:1406	arg1	potential					1432:1440	good clinical transformation potential	1403:1440	good clinical transformation potential	1403:1440	Therefore, PCHgel showed good clinical transformation potential with high efficacy, good safety, and ease of use.					
37179492	0	48	theme	Tissue	98:103	arg1	Adhesions					105:113	Post-Operative Tissue Adhesions	83:113	Post-Operative Tissue Adhesions	83:113	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin Effectively Prevents Post-Operative Tissue Adhesions.					
37179492	9	49	theme	suppression	1304:1314	arg1	mechanism					1316:1324	Its adhesion suppression mechanism	1291:1324	Its adhesion suppression mechanism	1291:1324	Its adhesion suppression mechanism was verified, and it also displayed good biosafety.					
37179492	7	50	theme	stable	1005:1010	arg1	barrier					1026:1032	a stable self-healable barrier	1003:1032	a stable self-healable barrier	1003:1032	The introduction of CMCS enabled hydrogels to form a stable self-healable barrier at injured positions and slowly release heparin during the wound healing period before being degraded after ∼14 days.					
37179492	1	51	theme	severe	170:175	arg1	adhesions					184:192	severe tissue adhesions	170:192	severe tissue adhesions	170:192	Tissue adhesions could occur following surgeries, and severe tissue adhesions can lead to serious complications.					
37179492	0	52	theme	Post-Operative	83:96	arg1	Adhesions					105:113	Post-Operative Tissue Adhesions	83:113	Post-Operative Tissue Adhesions	83:113	Degradable Temperature-Sensitive Hydrogel Loaded with Heparin Effectively Prevents Post-Operative Tissue Adhesions.					
37179492	6	53	theme	temperature	932:942	arg1	change					944:949	temperature change	932:949	temperature change	932:949	PCHgel presents as a flowable liquid below 20 °C and could rapidly transform into gel when spread on the surface of damaged tissue due to temperature change.					
37179492	1	54	theme	tissue	177:182	arg1	adhesions					184:192	severe tissue adhesions	170:192	severe tissue adhesions	170:192	Tissue adhesions could occur following surgeries, and severe tissue adhesions can lead to serious complications.					
35344350	12	0	theme	environmental	1402:1414	arg1	sustainability					1416:1429	its environmental sustainability	1398:1429	its environmental sustainability	1398:1429	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	6	1	contain	had	703:705	arg1	aerogel					695:701	PCNF composite aerogel	680:701	PCNF composite aerogel	680:701	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	6	1	contain	had	703:705	arg2	resilience					712:721	good resilience	707:721	good resilience	707:721	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	1	2	theme	composite	138:146	arg1	aerogel					148:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	4	3	theme	low	508:510	arg1	density					517:523	low bulk density	508:523	low bulk density (27.2 mg/cm3)	508:537	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	3	theme	low	508:510	arg1	mg/cm3					531:536	27.2 mg/cm3	526:536	27.2 mg/cm3	526:536	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	12	4	theme	potential	1345:1353	arg1	application					1355:1365	potential application	1345:1365	potential application	1345:1365	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	5	5	theme	improved	572:579	arg1	properties					592:601	improved mechanical properties	572:601	improved mechanical properties	572:601	The composite aerogel exhibited improved mechanical properties, which were almost three times compared with those of CNF aerogel.					
35344350	6	6	theme	wet	731:733	arg1	state					735:739	a wet state	729:739	a wet state	729:739	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	8	7	theme	dye	919:921	arg1	concentration					923:935	an initial dye concentration	908:935	an initial dye concentration of 50 mg/L	908:946	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	4	8	theme	composite	447:455	arg1	aerogels					457:464	The PCNF composite aerogels	438:464	The PCNF composite aerogels	438:464	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	5	9	theme	mechanical	581:590	arg1	properties					592:601	improved mechanical properties	572:601	improved mechanical properties	572:601	The composite aerogel exhibited improved mechanical properties, which were almost three times compared with those of CNF aerogel.					
35344350	2	10	theme	calcium	273:279	arg1	ion					281:283	calcium ion	273:283	calcium ion followed by immersion in dopamine solution	273:326	First, the CNF hydrogel was crosslinked by calcium ion followed by immersion in dopamine solution.					
35344350	7	11	theme	adsorption	791:800	arg1	capacities					802:811	the adsorption capacities	787:811	the adsorption capacities of the composite aerogel for methylene blue (MB)	787:860	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	12	12	theme	energy	1439:1444	arg1	consumption					1446:1456	low energy consumption	1435:1456	low energy consumption	1435:1456	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	11	13	theme	removal	1213:1219	arg1	efficiency					1221:1230	the removal efficiency	1209:1230	the removal efficiency of the composite aerogel	1209:1255	The reuse experiment showed that the removal efficiency of the composite aerogel remained higher than 85% after five cycles.					
35344350	9	14	theme	adsorption	953:962	arg1	isotherm					964:971	adsorption isotherm	953:971	adsorption isotherm	953:971	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	4	15	theme	bulk	512:515	arg1	density					517:523	low bulk density	508:523	low bulk density (27.2 mg/cm3)	508:537	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	15	theme	bulk	512:515	arg1	mg/cm3					531:536	27.2 mg/cm3	526:536	27.2 mg/cm3	526:536	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	5	16	theme	CNF	657:659	arg1	aerogel					661:667	CNF aerogel	657:667	CNF aerogel	657:667	The composite aerogel exhibited improved mechanical properties, which were almost three times compared with those of CNF aerogel.					
35344350	8	17	theme	mg/L	943:946	arg1	concentration					923:935	an initial dye concentration	908:935	an initial dye concentration of 50 mg/L	908:946	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	8	18	theme	MB	889:890	arg1	mg/g					900:903	208 mg/g	896:903	208 mg/g	896:903	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	8	18	theme	MB	889:890	arg1	adsorption					875:884	The maximum adsorption	863:884	The maximum adsorption of MB	863:890	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	4	19	contain	had	466:468	arg2	areas					484:488	large surface areas	470:488	large surface areas (368.15 m2/g)	470:502	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	19	contain	had	466:468	arg2	mg/cm3					531:536	27.2 mg/cm3	526:536	27.2 mg/cm3	526:536	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	19	contain	had	466:468	arg2	density					517:523	low bulk density	508:523	low bulk density (27.2 mg/cm3)	508:537	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	19	contain	had	466:468	arg2	m2/g					498:501	368.15 m2/g	491:501	368.15 m2/g	491:501	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	19	contain	had	466:468	arg1	aerogels					457:464	The PCNF composite aerogels	438:464	The PCNF composite aerogels	438:464	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	12	20	theme	low	1435:1437	arg1	consumption					1446:1456	low energy consumption	1435:1456	low energy consumption	1435:1456	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	12	21	theme	composite	1317:1325	arg1	aerogels					1327:1334	PCNF composite aerogels	1312:1334	PCNF composite aerogels	1312:1334	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	9	22	with	consistent	1025:1034	arg1	Langmuir					1041:1048	Langmuir	1041:1048	Langmuir	1041:1048	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	9	22	with	consistent	1025:1034	arg1	models					1074:1079	pseudo-second-order models	1054:1079	pseudo-second-order models	1054:1079	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	6	23	theme	good	707:710	arg1	resilience					712:721	good resilience	707:721	good resilience	707:721	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	7	24	theme	functional	750:759	arg1	layer					761:765	The PDA functional layer	742:765	The PDA functional layer	742:765	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	3	25	theme	PDA	404:406	arg1	aerogel					429:435	PDA@CNF (PCNF) composite aerogel	404:435	PDA@CNF (PCNF) composite aerogel	404:435	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	0	26	theme	Cellulose	22:30	arg1	Aerogel					53:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel	0:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	12	27	theme	PCNF	1312:1315	arg1	aerogels					1327:1334	PCNF composite aerogels	1312:1334	PCNF composite aerogels	1312:1334	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	5	28	theme	composite	544:552	arg1	aerogel					554:560	The composite aerogel	540:560	The composite aerogel	540:560	The composite aerogel exhibited improved mechanical properties, which were almost three times compared with those of CNF aerogel.					
35344350	7	29	theme	blue	852:855	arg1	methylene					842:850	methylene blue	842:855	methylene blue (MB)	842:860	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	7	29	theme	blue	852:855	arg1	MB					858:859	MB	858:859	MB	858:859	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	9	30	theme	kinetic	977:983	arg1	behaviors					985:993	kinetic behaviors	977:993	kinetic behaviors	977:993	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	0	31	theme	Polydopamine-Modified	0:20	arg1	Aerogel					53:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel	0:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	12	32	theme	wastewater	1370:1379	arg1	treatment					1381:1389	wastewater treatment	1370:1389	wastewater treatment due to its environmental sustainability and low energy consumption	1370:1456	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	12	33	contain	have	1340:1343	arg2	application					1355:1365	potential application	1345:1365	potential application	1345:1365	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	12	33	contain	have	1340:1343	arg1	aerogels					1327:1334	PCNF composite aerogels	1312:1334	PCNF composite aerogels	1312:1334	Therefore, PCNF composite aerogels may have potential application in wastewater treatment due to its environmental sustainability and low energy consumption.					
35344350	8	34	theme	initial	911:917	arg1	concentration					923:935	an initial dye concentration	908:935	an initial dye concentration of 50 mg/L	908:946	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	0	35	theme	Composite	43:51	arg1	Aerogel					53:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel	0:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	8	36	from	concentration	923:935	arg1	mg/g					900:903	208 mg/g	896:903	208 mg/g	896:903	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	8	36	from	concentration	923:935	arg1	adsorption					875:884	The maximum adsorption	863:884	The maximum adsorption of MB	863:890	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	6	37	theme	composite	685:693	arg1	aerogel					695:701	PCNF composite aerogel	680:701	PCNF composite aerogel	680:701	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	10	38	theme	high	1129:1132	arg1	capacity					1145:1152	a high adsorption capacity	1127:1152	a high adsorption capacity	1127:1152	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	7	39	theme	PDA	746:748	arg1	layer					761:765	The PDA functional layer	742:765	The PDA functional layer	742:765	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	1	40	theme	green	179:183	arg1	strategy					220:227	a green and facile mussel-inspired coating strategy	177:227	a green and facile mussel-inspired coating strategy	177:227	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	0	41	theme	Nanofibril	32:41	arg1	Aerogel					53:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel	0:59	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	10	42	contain	had	1123:1125	arg2	capacity					1145:1152	a high adsorption capacity	1127:1152	a high adsorption capacity	1127:1152	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	10	42	contain	had	1123:1125	arg1	aerogels					1114:1121	the PCNF composite aerogels	1095:1121	the PCNF composite aerogels	1095:1121	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	3	43	theme	PCNF	413:416	arg1	aerogel					429:435	PDA@CNF (PCNF) composite aerogel	404:435	PDA@CNF (PCNF) composite aerogel	404:435	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	11	44	theme	aerogel	1249:1255	arg1	efficiency					1221:1230	the removal efficiency	1209:1230	the removal efficiency of the composite aerogel	1209:1255	The reuse experiment showed that the removal efficiency of the composite aerogel remained higher than 85% after five cycles.					
35344350	3	45	theme	@	407:407	arg1	aerogel					429:435	PDA@CNF (PCNF) composite aerogel	404:435	PDA@CNF (PCNF) composite aerogel	404:435	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	9	46	theme	composite	1002:1010	arg1	aerogel					1012:1018	the composite aerogel	998:1018	the composite aerogel	998:1018	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	1	47	theme	facile	189:194	arg1	strategy					220:227	a green and facile mussel-inspired coating strategy	177:227	a green and facile mussel-inspired coating strategy	177:227	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	10	48	theme	adsorption	1134:1143	arg1	capacity					1145:1152	a high adsorption capacity	1127:1152	a high adsorption capacity	1127:1152	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	4	49	theme	large	470:474	arg1	areas					484:488	large surface areas	470:488	large surface areas (368.15 m2/g)	470:502	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	49	theme	large	470:474	arg1	m2/g					498:501	368.15 m2/g	491:501	368.15 m2/g	491:501	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	10	50	theme	composite	1104:1112	arg1	aerogels					1114:1121	the PCNF composite aerogels	1095:1121	the PCNF composite aerogels	1095:1121	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	9	51	theme	aerogel	1012:1018	arg1	isotherm					964:971	adsorption isotherm	953:971	adsorption isotherm	953:971	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	9	51	theme	aerogel	1012:1018	arg1	behaviors					985:993	kinetic behaviors	977:993	kinetic behaviors	977:993	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	6	52	theme	PCNF	680:683	arg1	aerogel					695:701	PCNF composite aerogel	680:701	PCNF composite aerogel	680:701	Moreover, PCNF composite aerogel had good resilience under a wet state.					
35344350	1	53	theme	mussel-inspired	196:210	arg1	strategy					220:227	a green and facile mussel-inspired coating strategy	177:227	a green and facile mussel-inspired coating strategy	177:227	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	0	54	theme	Effective	65:73	arg1	Dye					75:77	An Effective Dye Adsorbent	62:87	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	1	55	theme	new	107:109	arg1	aerogel					148:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	11	56	theme	composite	1239:1247	arg1	aerogel					1249:1255	the composite aerogel	1235:1255	the composite aerogel	1235:1255	The reuse experiment showed that the removal efficiency of the composite aerogel remained higher than 85% after five cycles.					
35344350	0	57	dep	Aerogel	53:59	arg1	Dye					75:77	An Effective Dye Adsorbent	62:87	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	1	58	theme	cellulose	111:119	arg1	aerogel					148:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	7	59	theme	aerogel	830:836	arg1	capacities					802:811	the adsorption capacities	787:811	the adsorption capacities of the composite aerogel for methylene blue (MB)	787:860	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	4	60	theme	surface	476:482	arg1	areas					484:488	large surface areas	470:488	large surface areas (368.15 m2/g)	470:502	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	4	60	theme	surface	476:482	arg1	m2/g					498:501	368.15 m2/g	491:501	368.15 m2/g	491:501	The PCNF composite aerogels had large surface areas (368.15 m2/g) and low bulk density (27.2 mg/cm3).					
35344350	10	61	theme	pH	1166:1167	arg1	range					1169:1173	a wide pH range	1159:1173	a wide pH range	1159:1173	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35344350	9	62	dep	isotherm	964:971	arg1	The					949:951	The	949:951	The	949:951	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	1	63	theme	nanofibril	121:130	arg1	aerogel					148:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	9	64	theme	pseudo-second-order	1054:1072	arg1	models					1074:1079	pseudo-second-order models	1054:1079	pseudo-second-order models	1054:1079	The adsorption isotherm and kinetic behaviors of the composite aerogel were consistent with Langmuir and pseudo-second-order models.					
35344350	1	65	theme	coating	212:218	arg1	strategy					220:227	a green and facile mussel-inspired coating strategy	177:227	a green and facile mussel-inspired coating strategy	177:227	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	11	66	theme	reuse	1180:1184	arg1	experiment					1186:1195	The reuse experiment	1176:1195	The reuse experiment	1176:1195	The reuse experiment showed that the removal efficiency of the composite aerogel remained higher than 85% after five cycles.					
35344350	2	67	theme	CNF	241:243	arg1	hydrogel					245:252	the CNF hydrogel	237:252	the CNF hydrogel	237:252	First, the CNF hydrogel was crosslinked by calcium ion followed by immersion in dopamine solution.					
35344350	3	68	theme	composite	419:427	arg1	aerogel					429:435	PDA@CNF (PCNF) composite aerogel	404:435	PDA@CNF (PCNF) composite aerogel	404:435	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	2	69	theme	dopamine	310:317	arg1	solution					319:326	dopamine solution	310:326	dopamine solution	310:326	First, the CNF hydrogel was crosslinked by calcium ion followed by immersion in dopamine solution.					
35344350	0	70	theme	Adsorbent	79:87	arg1	Dye					75:77	An Effective Dye Adsorbent	62:87	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.	0:88	Polydopamine-Modified Cellulose Nanofibril Composite Aerogel: An Effective Dye Adsorbent.					
35344350	3	71	theme	CNF	408:410	arg1	aerogel					429:435	PDA@CNF (PCNF) composite aerogel	404:435	PDA@CNF (PCNF) composite aerogel	404:435	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	1	72	theme	CNF	133:135	arg1	aerogel					148:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	a new cellulose nanofibril (CNF) composite aerogel	105:154	In this study, a new cellulose nanofibril (CNF) composite aerogel was fabricated using a green and facile mussel-inspired coating strategy.					
35344350	7	73	theme	composite	820:828	arg1	aerogel					830:836	the composite aerogel	816:836	the composite aerogel	816:836	The PDA functional layer remarkably enhanced the adsorption capacities of the composite aerogel for methylene blue (MB).					
35344350	3	74	theme	CNF	352:354	arg1	surface					341:347	the surface	337:347	the surface of CNF	337:354	Second, the surface of CNF was modified using polydopamine (PDA) to obtain PDA@CNF (PCNF) composite aerogel.					
35344350	8	75	theme	maximum	867:873	arg1	mg/g					900:903	208 mg/g	896:903	208 mg/g	896:903	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	8	75	theme	maximum	867:873	arg1	adsorption					875:884	The maximum adsorption	863:884	The maximum adsorption of MB	863:890	The maximum adsorption of MB was 208 mg/g at an initial dye concentration of 50 mg/L.					
35344350	10	76	theme	wide	1161:1164	arg1	range					1169:1173	a wide pH range	1159:1173	a wide pH range	1159:1173	In addition, the PCNF composite aerogels had a high adsorption capacity over a wide pH range.					
35715009	0	0	theme	A.	75:76	arg1	strain					88:93	a domestic A. pullulans strain	64:93	a domestic A. pullulans strain	64:93	Optimization of hazelnut husk medium for pullulan production by a domestic A. pullulans strain.					
35715009	3	1	theme	dried	307:311	arg1	hydrolysate					327:337	dried hazelnut husk hydrolysate	307:337	dried hazelnut husk hydrolysate	307:337	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	1	theme	dried	307:311	arg1	medium					373:378	fermentation medium	360:378	fermentation medium	360:378	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	5	2	theme	2SO4	624:627	arg1	concentration					629:641	(NH4)2SO4 concentration	619:641	(NH4)2SO4 concentration	619:641	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	12	3	theme	pullulan	1412:1419	arg1	production					1421:1430	pullulan production	1412:1430	pullulan production by A. pullulans	1412:1446	No previous work was found to utilize dried hazelnut husk as fermentation medium for pullulan production by A. pullulans.					
35715009	1	4	theme	abundant	129:136	arg1	residue					151:157	the most abundant agricultural residue	120:157	the most abundant agricultural residue in Turkey	120:167	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	0	5	theme	domestic	66:73	arg1	strain					88:93	a domestic A. pullulans strain	64:93	a domestic A. pullulans strain	64:93	Optimization of hazelnut husk medium for pullulan production by a domestic A. pullulans strain.					
35715009	4	6	theme	fermentation	503:514	arg1	parameters					523:532	some fermentation medium parameters	498:532	some fermentation medium parameters	498:532	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	5	7	theme	concentration	629:641	arg1	effects					608:614	The effects	604:614	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production	604:737	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	1	8	theme	agricultural	138:149	arg1	residue					151:157	the most abundant agricultural residue	120:157	the most abundant agricultural residue in Turkey	120:167	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	4	9	theme	surface	577:583	arg1	RSM					598:600	RSM	598:600	RSM	598:600	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	4	9	theme	surface	577:583	arg1	methodology					585:595	response surface methodology	568:595	response surface methodology (RSM)	568:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	5	10	theme	ground	695:700	arg1	husk					711:714	ground hazelnut husk	695:714	ground hazelnut husk	695:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	11	11	theme	novel	1258:1262	arg1	substrate					1264:1272	the novel substrate	1254:1272	the novel substrate for production of the pullulan by A. pullulans AZ-6	1254:1324	This study showed that hazelnut husk was one of the novel substrate for production of the pullulan by A. pullulans AZ-6.					
35715009	0	12	theme	pullulans	78:86	arg1	strain					88:93	a domestic A. pullulans strain	64:93	a domestic A. pullulans strain	64:93	Optimization of hazelnut husk medium for pullulan production by a domestic A. pullulans strain.					
35715009	4	13	theme	work	469:472	arg1	aim					457:459	The aim	453:459	The aim of this work	453:472	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	4	13	theme	work	469:472	arg1	optimization					482:493	the optimization	478:493	the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM)	478:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	11	14	theme	substrate	1264:1272	arg1	one					1247:1249	one	1247:1249	one	1247:1249	This study showed that hazelnut husk was one of the novel substrate for production of the pullulan by A. pullulans AZ-6.					
35715009	11	14	theme	substrate	1264:1272	arg1	substrate					1264:1272	the novel substrate	1254:1272	the novel substrate for production of the pullulan by A. pullulans AZ-6	1254:1324	This study showed that hazelnut husk was one of the novel substrate for production of the pullulan by A. pullulans AZ-6.					
35715009	2	15	theme	pullulan	282:289	arg1	production					268:277	economical production	257:277	economical production of pullulan	257:289	Valorization of this lignocellulosic biomass would provide a promoting alternative for economical production of pullulan.					
35715009	5	16	theme	husk	711:714	arg1	husk					711:714	ground hazelnut husk	695:714	ground hazelnut husk	695:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	16	theme	husk	711:714	arg1	concentration					629:641	(NH4)2SO4 concentration	619:641	(NH4)2SO4 concentration	619:641	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	16	theme	husk	711:714	arg1	volume					648:653	the volume	644:653	the volume of concentrated H2SO4	644:675	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	16	theme	husk	711:714	arg1	H2SO4					671:675	concentrated H2SO4	658:675	concentrated H2SO4	658:675	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	16	theme	husk	711:714	arg1	amount					685:690	the amount	681:690	the amount of ground hazelnut husk	681:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	3	17	used	used	343:346	arg2	hydrolysate					327:337	dried hazelnut husk hydrolysate	307:337	dried hazelnut husk hydrolysate	307:337	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	17	used	used	343:346	arg2	medium					373:378	fermentation medium	360:378	fermentation medium	360:378	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	6	18	theme	optimum	766:772	arg1	levels					774:779	The optimum levels	762:779	The optimum levels of the fermentation parameters	762:810	The optimum levels of the fermentation parameters defined as 7.2 gL-1, 2.5 mL and 20 g, respectively.					
35715009	10	19	theme	synthesized	1161:1171	arg1	pullulan					1173:1180	synthesized pullulan	1161:1180	synthesized pullulan	1161:1180	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	1	20	theme	residue	151:157	arg1	one					113:115	one	113:115	one	113:115	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	1	20	theme	residue	151:157	arg1	residue					151:157	the most abundant agricultural residue	120:157	the most abundant agricultural residue in Turkey	120:167	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	8	21	theme	strain	1031:1036	arg1	0.097 h-1					1051:1059	0.097 h-1	1051:1059	0.097 h-1	1051:1059	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	8	21	theme	strain	1031:1036	arg1	rate					1019:1022	Specific growth rate	1003:1022	Specific growth rate of the strain	1003:1036	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	9	22	theme	FTIR	1062:1065	arg1	attributes					1076:1085	FTIR spectral attributes	1062:1085	FTIR spectral attributes	1062:1085	FTIR spectral attributes confirmed the structure of pullulan.					
35715009	3	23	theme	pullulans	442:450	arg1	strain					418:423	a domestic strain	407:423	a domestic strain of Aureobasidium pullulans	407:450	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	24	theme	hazelnut	313:320	arg1	hydrolysate					327:337	dried hazelnut husk hydrolysate	307:337	dried hazelnut husk hydrolysate	307:337	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	24	theme	hazelnut	313:320	arg1	medium					373:378	fermentation medium	360:378	fermentation medium	360:378	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	5	25	theme	NH4	620:622	arg1	concentration					629:641	(NH4)2SO4 concentration	619:641	(NH4)2SO4 concentration	619:641	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	26	theme	pullulan	719:726	arg1	production					728:737	pullulan production	719:737	pullulan production	719:737	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	9	27	theme	spectral	1067:1074	arg1	attributes					1076:1085	FTIR spectral attributes	1062:1085	FTIR spectral attributes	1062:1085	FTIR spectral attributes confirmed the structure of pullulan.					
35715009	3	28	theme	pullulan	384:391	arg1	production					393:402	pullulan production	384:402	pullulan production by a domestic strain of Aureobasidium pullulans	384:450	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	10	29	theme	Thermal	1124:1130	arg1	temperature					1146:1156	Thermal decomposition temperature	1124:1156	Thermal decomposition temperature of synthesized pullulan	1124:1180	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	10	29	theme	Thermal	1124:1130	arg1	247.15 °C					1195:1203	247.15 °C	1195:1203	247.15 °C	1195:1203	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	7	30	theme	exopolysaccharide	889:905	arg1	74.39					941:945	74.39	941:945	74.39	941:945	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	30	theme	exopolysaccharide	889:905	arg1	pullulan					876:883	The maximum pullulan and exopolysaccharide concentrations	864:920	pullulan	876:883	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	30	theme	exopolysaccharide	889:905	arg1	concentrations					907:920	The maximum pullulan and exopolysaccharide concentrations	864:920	concentrations	907:920	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	30	theme	exopolysaccharide	889:905	arg1	75.95 gL-1					951:960	75.95 gL-1	951:960	75.95 gL-1	951:960	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	11	31	theme	pullulan	1296:1303	arg1	production					1278:1287	production	1278:1287	production of the pullulan by A. pullulans AZ-6	1278:1324	This study showed that hazelnut husk was one of the novel substrate for production of the pullulan by A. pullulans AZ-6.					
35715009	8	32	theme	growth	1012:1017	arg1	0.097 h-1					1051:1059	0.097 h-1	1051:1059	0.097 h-1	1051:1059	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	8	32	theme	growth	1012:1017	arg1	rate					1019:1022	Specific growth rate	1003:1022	Specific growth rate of the strain	1003:1036	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	3	33	theme	fermentation	360:371	arg1	hydrolysate					327:337	dried hazelnut husk hydrolysate	307:337	dried hazelnut husk hydrolysate	307:337	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	33	theme	fermentation	360:371	arg1	medium					373:378	fermentation medium	360:378	fermentation medium	360:378	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	4	34	theme	composite	545:553	arg1	design					555:560	central composite design	537:560	central composite design using response surface methodology (RSM)	537:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	11	35	theme	hazelnut	1229:1236	arg1	husk					1238:1241	hazelnut husk	1229:1241	hazelnut husk	1229:1241	This study showed that hazelnut husk was one of the novel substrate for production of the pullulan by A. pullulans AZ-6.					
35715009	12	36	theme	dried	1365:1369	arg1	husk					1380:1383	dried hazelnut husk	1365:1383	dried hazelnut husk	1365:1383	No previous work was found to utilize dried hazelnut husk as fermentation medium for pullulan production by A. pullulans.					
35715009	0	37	theme	hazelnut	16:23	arg1	Optimization					0:11	Optimization	0:11	Optimization of hazelnut	0:23	Optimization of hazelnut husk medium for pullulan production by a domestic A. pullulans strain.					
35715009	4	38	theme	response	568:575	arg1	RSM					598:600	RSM	598:600	RSM	598:600	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	4	38	theme	response	568:575	arg1	methodology					585:595	response surface methodology	568:595	response surface methodology (RSM)	568:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	12	39	theme	fermentation	1388:1399	arg1	medium					1401:1406	fermentation medium	1388:1406	fermentation medium for pullulan production by A. pullulans	1388:1446	No previous work was found to utilize dried hazelnut husk as fermentation medium for pullulan production by A. pullulans.					
35715009	1	40	theme	Hazelnut	96:103	arg1	husk					105:108	Hazelnut husk	96:108	Hazelnut husk	96:108	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	5	41	theme	amount	685:690	arg1	effects					608:614	The effects	604:614	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production	604:737	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	12	42	theme	previous	1330:1337	arg1	work					1339:1342	No previous work	1327:1342	No previous work	1327:1342	No previous work was found to utilize dried hazelnut husk as fermentation medium for pullulan production by A. pullulans.					
35715009	12	43	theme	hazelnut	1371:1378	arg1	husk					1380:1383	dried hazelnut husk	1365:1383	dried hazelnut husk	1365:1383	No previous work was found to utilize dried hazelnut husk as fermentation medium for pullulan production by A. pullulans.					
35715009	3	44	theme	Aureobasidium	428:440	arg1	pullulans					442:450	Aureobasidium pullulans	428:450	Aureobasidium pullulans	428:450	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	4	45	theme	parameters	523:532	arg1	aim					457:459	The aim	453:459	The aim of this work	453:472	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	4	45	theme	parameters	523:532	arg1	optimization					482:493	the optimization	478:493	the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM)	478:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	3	46	theme	domestic	409:416	arg1	strain					418:423	a domestic strain	407:423	a domestic strain of Aureobasidium pullulans	407:450	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	4	47	theme	medium	516:521	arg1	parameters					523:532	some fermentation medium parameters	498:532	some fermentation medium parameters	498:532	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	5	48	theme	volume	648:653	arg1	effects					608:614	The effects	604:614	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production	604:737	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	10	49	theme	pullulan	1173:1180	arg1	temperature					1146:1156	Thermal decomposition temperature	1124:1156	Thermal decomposition temperature of synthesized pullulan	1124:1180	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	10	49	theme	pullulan	1173:1180	arg1	247.15 °C					1195:1203	247.15 °C	1195:1203	247.15 °C	1195:1203	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	9	50	theme	pullulan	1114:1121	arg1	structure					1101:1109	the structure	1097:1109	the structure of pullulan	1097:1121	FTIR spectral attributes confirmed the structure of pullulan.					
35715009	0	51	theme	pullulan	41:48	arg1	production					50:59	pullulan production	41:59	pullulan production by a domestic A. pullulans strain	41:93	Optimization of hazelnut husk medium for pullulan production by a domestic A. pullulans strain.					
35715009	4	52	theme	central	537:543	arg1	design					555:560	central composite design	537:560	central composite design using response surface methodology (RSM)	537:601	The aim of this work was the optimization of some fermentation medium parameters by central composite design using response surface methodology (RSM).					
35715009	2	53	theme	lignocellulosic	191:205	arg1	biomass					207:213	this lignocellulosic biomass	186:213	this lignocellulosic biomass	186:213	Valorization of this lignocellulosic biomass would provide a promoting alternative for economical production of pullulan.					
35715009	2	54	theme	biomass	207:213	arg1	Valorization					170:181	Valorization	170:181	Valorization of this lignocellulosic biomass	170:213	Valorization of this lignocellulosic biomass would provide a promoting alternative for economical production of pullulan.					
35715009	7	55	theme	optimum	983:989	arg1	conditions					991:1000	the optimum conditions	979:1000	the optimum conditions	979:1000	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	10	56	theme	decomposition	1132:1144	arg1	temperature					1146:1156	Thermal decomposition temperature	1124:1156	Thermal decomposition temperature of synthesized pullulan	1124:1180	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	10	56	theme	decomposition	1132:1144	arg1	247.15 °C					1195:1203	247.15 °C	1195:1203	247.15 °C	1195:1203	Thermal decomposition temperature of synthesized pullulan was found as 247.15 °C.					
35715009	5	57	theme	concentrated	658:669	arg1	H2SO4					671:675	concentrated H2SO4	658:675	concentrated H2SO4	658:675	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	2	58	theme	economical	257:266	arg1	production					268:277	economical production	257:277	economical production of pullulan	257:289	Valorization of this lignocellulosic biomass would provide a promoting alternative for economical production of pullulan.					
35715009	5	59	theme	H2SO4	671:675	arg1	husk					711:714	ground hazelnut husk	695:714	ground hazelnut husk	695:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	59	theme	H2SO4	671:675	arg1	concentration					629:641	(NH4)2SO4 concentration	619:641	(NH4)2SO4 concentration	619:641	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	59	theme	H2SO4	671:675	arg1	volume					648:653	the volume	644:653	the volume of concentrated H2SO4	644:675	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	59	theme	H2SO4	671:675	arg1	H2SO4					671:675	concentrated H2SO4	658:675	concentrated H2SO4	658:675	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	59	theme	H2SO4	671:675	arg1	amount					685:690	the amount	681:690	the amount of ground hazelnut husk	681:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	6	60	theme	parameters	801:810	arg1	levels					774:779	The optimum levels	762:779	The optimum levels of the fermentation parameters	762:810	The optimum levels of the fermentation parameters defined as 7.2 gL-1, 2.5 mL and 20 g, respectively.					
35715009	8	61	theme	Specific	1003:1010	arg1	0.097 h-1					1051:1059	0.097 h-1	1051:1059	0.097 h-1	1051:1059	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	8	61	theme	Specific	1003:1010	arg1	rate					1019:1022	Specific growth rate	1003:1022	Specific growth rate of the strain	1003:1036	Specific growth rate of the strain was found as 0.097 h-1.					
35715009	3	62	theme	husk	322:325	arg1	hydrolysate					327:337	dried hazelnut husk hydrolysate	307:337	dried hazelnut husk hydrolysate	307:337	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	3	62	theme	husk	322:325	arg1	medium					373:378	fermentation medium	360:378	fermentation medium	360:378	In this study, dried hazelnut husk hydrolysate was used directly as fermentation medium for pullulan production by a domestic strain of Aureobasidium pullulans.					
35715009	6	63	theme	fermentation	788:799	arg1	parameters					801:810	the fermentation parameters	784:810	the fermentation parameters	784:810	The optimum levels of the fermentation parameters defined as 7.2 gL-1, 2.5 mL and 20 g, respectively.					
35715009	7	64	theme	maximum	868:874	arg1	74.39					941:945	74.39	941:945	74.39	941:945	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	64	theme	maximum	868:874	arg1	pullulan					876:883	The maximum pullulan and exopolysaccharide concentrations	864:920	pullulan	876:883	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	64	theme	maximum	868:874	arg1	concentrations					907:920	The maximum pullulan and exopolysaccharide concentrations	864:920	concentrations	907:920	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	7	64	theme	maximum	868:874	arg1	75.95 gL-1					951:960	75.95 gL-1	951:960	75.95 gL-1	951:960	The maximum pullulan and exopolysaccharide concentrations were determined as 74.39 and 75.95 gL-1, respectively in the optimum conditions.					
35715009	2	65	theme	promoting	231:239	arg1	alternative					241:251	a promoting alternative	229:251	a promoting alternative for economical production of pullulan	229:289	Valorization of this lignocellulosic biomass would provide a promoting alternative for economical production of pullulan.					
35715009	1	66	from	residue	151:157	arg1	Turkey					162:167	Turkey	162:167	Turkey	162:167	Hazelnut husk is one of the most abundant agricultural residue in Turkey.					
35715009	5	67	from	effects	608:614	arg1	production					728:737	pullulan production	719:737	pullulan production	719:737	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35715009	5	68	theme	hazelnut	702:709	arg1	husk					711:714	ground hazelnut husk	695:714	ground hazelnut husk	695:714	The effects of (NH4)2SO4 concentration, the volume of concentrated H2SO4 and the amount of ground hazelnut husk on pullulan production were optimized by RSM.					
35798078	4	0	theme	%	678:678	arg1	CA					685:686	5 % TiO2 CA	676:686	5 % TiO2 CA	676:686	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	1	1	theme	cellulose	165:173	arg1	polymers					205:212	biodegradable polymers	191:212	biodegradable polymers	191:212	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	1	theme	cellulose	165:173	arg1	acid					150:153	Polylactic acid	139:153	Polylactic acid (PLA)	139:159	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	1	theme	cellulose	165:173	arg1	CA					184:185	CA	184:185	CA	184:185	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	1	theme	cellulose	165:173	arg1	acetate					175:181	cellulose acetate	165:181	cellulose acetate (CA)	165:186	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	2	2	with	PLA	319:321	arg1	TiO2					351:354	TiO2	351:354	TiO2	351:354	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	0	3	theme	acid	96:99	arg1	properties					29:38	Antibacterial and degradable properties	0:38	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid	0:99	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	6	4	dep	PLA	937:939	arg1	films					958:962	composite films	948:962	composite films	948:962	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	7	5	theme	5 	1059:1060	arg1	%					1061:1061	%	1061:1061	%	1061:1061	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	4	6	theme	5 	676:677	arg1	%					678:678	%	678:678	%	678:678	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	5	7	theme	βCD-modified	720:731	arg1	NPs					738:740	βCD-modified TiO2 NPs	720:740	βCD-modified TiO2 NPs	720:740	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	0	8	theme	food	123:126	arg1	packaging					128:136	food packaging	123:136	food packaging	123:136	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	6	9	theme	sorbic	852:857	arg1	acid					859:862	sorbic acid	852:862	sorbic acid (SA)	852:867	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	6	9	theme	sorbic	852:857	arg1	SA					865:866	SA	865:866	SA	865:866	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	8	10	theme	antimicrobial	1241:1253	arg1	packaging					1260:1268	antimicrobial food packaging	1241:1268	antimicrobial food packaging	1241:1268	CA composite films showed potential to be used as antimicrobial food packaging.					
35798078	4	11	theme	%	650:650	arg1	loss					667:670	5.1 % maximum weight loss	646:670	5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices	646:703	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	1	12	theme	innovative	263:272	arg1	materials					274:282	innovative materials	263:282	innovative materials across several industrial sectors	263:316	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	7	13	theme	%	1133:1133	arg1	inhibition					1135:1144	71 % inhibition	1130:1144	71 % inhibition of E. coli	1130:1155	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	5	14	theme	polymers	787:794	arg1	photo-degradation					756:772	the photo-degradation	752:772	the photo-degradation of the plain polymers to a lesser extent	752:813	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	3	15	theme	greater	546:552	arg1	variations					560:569	greater color variations	546:569	greater color variations	546:569	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	1	16	theme	materials	274:282	arg1	development					248:258	the development	244:258	the development of innovative materials across several industrial sectors	244:316	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	7	17	theme	aureus	1183:1188	arg1	inhibition					1166:1175	88 % inhibition	1161:1175	88 % inhibition of S. aureus	1161:1188	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	7	17	theme	aureus	1183:1188	arg1	inhibition					1135:1144	71 % inhibition	1130:1144	71 % inhibition of E. coli	1130:1155	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	6	18	theme	aureus	1031:1036	arg1	inactivation					979:990	inactivation	979:990	inactivation of Escherichia coli and Staphylococcus aureus	979:1036	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	3	19	theme	Thermo-	427:433	arg1	studies					457:463	Thermo- and photo-degradation studies	427:463	Thermo- and photo-degradation studies	427:463	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	2	20	theme	TiO2	403:406	arg1	NPs					408:410	β-cyclodextrin grafted TiO2 NPs	380:410	β-cyclodextrin grafted TiO2 NPs	380:410	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	6	21	theme	antibacterial	911:923	arg1	activity					925:932	the antibacterial activity	907:932	the antibacterial activity of PLA and CA composite films	907:962	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	6	22	theme	PLA	937:939	arg1	activity					925:932	the antibacterial activity	907:932	the antibacterial activity of PLA and CA composite films	907:962	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	8	23	theme	composite	1194:1202	arg1	films					1204:1208	CA composite films	1191:1208	CA composite films	1191:1208	CA composite films showed potential to be used as antimicrobial food packaging.					
35798078	3	24	theme	TiO2	534:537	arg1	TiO2					534:537	TiO2	534:537	TiO2	534:537	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	3	24	theme	TiO2	534:537	arg1	amount					524:529	higher amount	517:529	higher amount of TiO2	517:537	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	2	25	theme	grafted	395:401	arg1	NPs					408:410	β-cyclodextrin grafted TiO2 NPs	380:410	β-cyclodextrin grafted TiO2 NPs	380:410	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	5	26	theme	plain	781:785	arg1	polymers					787:794	the plain polymers	777:794	the plain polymers	777:794	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	6	27	theme	βCD-TiO2	890:897	arg1	NPs					899:901	βCD-TiO2 NPs	890:901	βCD-TiO2 NPs	890:901	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	4	28	theme	5.1 	646:649	arg1	%					650:650	%	650:650	%	650:650	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	2	29	theme	CA	327:328	arg1	films					340:344	CA composite films	327:344	CA composite films with TiO2	327:354	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	2	30	theme	β-cyclodextrin	380:393	arg1	NPs					408:410	β-cyclodextrin grafted TiO2 NPs	380:410	β-cyclodextrin grafted TiO2 NPs	380:410	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	0	31	theme	Antibacterial	0:12	arg1	properties					29:38	Antibacterial and degradable properties	0:38	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid	0:99	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	3	32	theme	structure	572:580	arg1	modifications					582:594	structure modifications	572:594	structure modifications	572:594	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	4	33	theme	maximum	652:658	arg1	loss					667:670	5.1 % maximum weight loss	646:670	5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices	646:703	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	1	34	theme	several	291:297	arg1	sectors					310:316	several industrial sectors	291:316	several industrial sectors	291:316	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	7	35	theme	%	1164:1164	arg1	inhibition					1166:1175	88 % inhibition	1161:1175	88 % inhibition of S. aureus	1161:1188	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	2	36	theme	PLA	319:321	arg1	NPs					371:373	NPs	371:373	NPs	371:373	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	2	36	theme	PLA	319:321	arg1	nanoparticles					356:368	PLA and CA composite films with TiO2 nanoparticles	319:368	PLA and CA composite films with TiO2 nanoparticles (NPs)	319:374	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	6	37	theme	coli	1007:1010	arg1	inactivation					979:990	inactivation	979:990	inactivation of Escherichia coli and Staphylococcus aureus	979:1036	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	1	38	theme	biodegradable	191:203	arg1	polymers					205:212	biodegradable polymers	191:212	biodegradable polymers	191:212	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	38	theme	biodegradable	191:203	arg1	acid					150:153	Polylactic acid	139:153	Polylactic acid (PLA)	139:159	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	38	theme	biodegradable	191:203	arg1	acetate					175:181	cellulose acetate	165:181	cellulose acetate (CA)	165:186	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	0	39	theme	degradable	18:27	arg1	properties					29:38	Antibacterial and degradable properties	0:38	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid	0:99	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	1	40	theme	industrial	299:308	arg1	sectors					310:316	several industrial sectors	291:316	several industrial sectors	291:316	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	2	41	with	films	340:344	arg1	TiO2					351:354	TiO2	351:354	TiO2	351:354	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	7	42	theme	88 	1161:1163	arg1	%					1164:1164	%	1164:1164	%	1164:1164	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	3	43	theme	PLA	483:485	arg1	films					494:498	PLA and CA films	483:498	PLA and CA films	483:498	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	0	44	theme	β-cyclodextrin-TiO2	43:61	arg1	acetate					73:79	β-cyclodextrin-TiO2 cellulose acetate	43:79	β-cyclodextrin-TiO2 cellulose acetate	43:79	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	4	45	theme	weight	660:665	arg1	loss					667:670	5.1 % maximum weight loss	646:670	5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices	646:703	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	6	46	theme	Benzoic	830:836	arg1	BA					844:845	BA	844:845	BA	844:845	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	6	46	theme	Benzoic	830:836	arg1	acid					838:841	Benzoic acid	830:841	Benzoic acid (BA)	830:846	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	3	47	theme	weight	600:605	arg1	losses					607:612	weight losses	600:612	weight losses	600:612	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	7	48	theme	%	1061:1061	arg1	NPs					1068:1070	5 % TiO2 NPs	1059:1070	5 % TiO2 NPs	1059:1070	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	3	49	theme	photo-degradation	439:455	arg1	studies					457:463	Thermo- and photo-degradation studies	427:463	Thermo- and photo-degradation studies	427:463	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	5	50	theme	TiO2	820:823	arg1	NPs					825:827	TiO2 NPs	820:827	TiO2 NPs	820:827	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	0	51	theme	acetate	73:79	arg1	properties					29:38	Antibacterial and degradable properties	0:38	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid	0:99	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	7	52	theme	71 	1130:1132	arg1	%					1133:1133	%	1133:1133	%	1133:1133	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	7	53	theme	coli	1152:1155	arg1	inhibition					1166:1175	88 % inhibition	1161:1175	88 % inhibition of S. aureus	1161:1188	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	7	53	theme	coli	1152:1155	arg1	inhibition					1135:1144	71 % inhibition	1130:1144	71 % inhibition of E. coli	1130:1155	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	1	54	theme	Polylactic	139:148	arg1	polymers					205:212	biodegradable polymers	191:212	biodegradable polymers	191:212	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	54	theme	Polylactic	139:148	arg1	PLA					156:158	PLA	156:158	PLA	156:158	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	54	theme	Polylactic	139:148	arg1	acid					150:153	Polylactic acid	139:153	Polylactic acid (PLA)	139:159	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	1	54	theme	Polylactic	139:148	arg1	acetate					175:181	cellulose acetate	165:181	cellulose acetate (CA)	165:186	Polylactic acid (PLA) and cellulose acetate (CA) as biodegradable polymers are being highly exploited in the development of innovative materials across several industrial sectors.					
35798078	0	55	theme	cellulose	63:71	arg1	acetate					73:79	β-cyclodextrin-TiO2 cellulose acetate	43:79	β-cyclodextrin-TiO2 cellulose acetate	43:79	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	7	56	theme	CA	1039:1040	arg1	film					1042:1045	CA film	1039:1045	CA film filled with 5 % TiO2 NPs	1039:1070	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	4	57	theme	TiO2	680:683	arg1	CA					685:686	5 % TiO2 CA	676:686	5 % TiO2 CA	676:686	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	7	58	theme	TiO2	1063:1066	arg1	NPs					1068:1070	5 % TiO2 NPs	1059:1070	5 % TiO2 NPs	1059:1070	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	6	59	theme	composite	948:956	arg1	films					958:962	composite films	948:962	composite films	948:962	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	2	60	theme	films	340:344	arg1	NPs					371:373	NPs	371:373	NPs	371:373	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	2	60	theme	films	340:344	arg1	nanoparticles					356:368	PLA and CA composite films with TiO2 nanoparticles	319:368	PLA and CA composite films with TiO2 nanoparticles (NPs)	319:374	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	3	61	theme	color	554:558	arg1	variations					560:569	greater color variations	546:569	greater color variations	546:569	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	8	62	theme	food	1255:1258	arg1	packaging					1260:1268	antimicrobial food packaging	1241:1268	antimicrobial food packaging	1241:1268	CA composite films showed potential to be used as antimicrobial food packaging.					
35798078	2	63	theme	composite	330:338	arg1	films					340:344	CA composite films	327:344	CA composite films with TiO2	327:354	PLA and CA composite films with TiO2 nanoparticles (NPs) and β-cyclodextrin grafted TiO2 NPs were prepared.					
35798078	4	64	theme	PLA	692:694	arg1	matrices					696:703	PLA matrices	692:703	PLA matrices	692:703	It has been observed 9.3 % and 5.1 % maximum weight loss for 5 % TiO2 CA and PLA matrices, respectively.					
35798078	0	65	theme	polylactic	85:94	arg1	acid					96:99	polylactic acid	85:99	polylactic acid	85:99	Antibacterial and degradable properties of β-cyclodextrin-TiO2 cellulose acetate and polylactic acid bionanocomposites for food packaging.					
35798078	5	66	theme	lesser	801:806	arg1	extent					808:813	a lesser extent	799:813	a lesser extent	799:813	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	3	67	theme	higher	517:522	arg1	TiO2					534:537	TiO2	534:537	TiO2	534:537	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	3	67	theme	higher	517:522	arg1	amount					524:529	higher amount	517:529	higher amount of TiO2	517:537	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	3	68	theme	CA	491:492	arg1	films					494:498	PLA and CA films	483:498	PLA and CA films	483:498	Thermo- and photo-degradation studies were performed on PLA and CA films and noticed that higher amount of TiO2 induce greater color variations, structure modifications and weight losses.					
35798078	6	69	theme	CA	945:946	arg1	activity					925:932	the antibacterial activity	907:932	the antibacterial activity of PLA and CA composite films	907:962	Benzoic acid (BA) and sorbic acid (SA) were incorporated to βCD-TiO2 NPs and the antibacterial activity of PLA and CA composite films was studied by inactivation of Escherichia coli and Staphylococcus aureus.					
35798078	5	70	theme	TiO2	733:736	arg1	NPs					738:740	βCD-modified TiO2 NPs	720:740	βCD-modified TiO2 NPs	720:740	βCD-modified TiO2 NPs increased the photo-degradation of the plain polymers to a lesser extent than TiO2 NPs.					
35798078	7	71	theme	highest	1086:1092	arg1	activity					1108:1115	the highest antibacterial activity	1082:1115	the highest antibacterial activity	1082:1115	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	7	72	theme	antibacterial	1094:1106	arg1	activity					1108:1115	the highest antibacterial activity	1082:1115	the highest antibacterial activity	1082:1115	CA film filled with 5 % TiO2 NPs presented the highest antibacterial activity and achieved 71 % inhibition of E. coli and 88 % inhibition of S. aureus.					
35798078	8	73	theme	CA	1191:1192	arg1	films					1204:1208	CA composite films	1191:1208	CA composite films	1191:1208	CA composite films showed potential to be used as antimicrobial food packaging.					
36446506	0	0	theme	carrageenan-based	83:99	arg1	films					111:115	Nanoparticle-filled carrageenan-based composite films	63:115	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.	0:116	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	7	1	theme	scavenging	1119:1128	arg1	activities					1130:1139	free radical scavenging activities	1106:1139	free radical scavenging activities	1106:1139	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36446506	7	2	theme	high	1067:1070	arg1	%					1084:1084	79.46 %	1078:1084	79.46 %	1078:1084	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36446506	7	2	theme	high	1067:1070	arg1	DPPH					1072:1075	relatively high DPPH	1056:1075	relatively high DPPH (79.46 %)	1056:1085	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36446506	2	3	theme	enhanced	376:383	arg1	activity					397:404	enhanced antioxidant activity	376:404	enhanced antioxidant activity	376:404	These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses.					
36446506	4	4	theme	mechanical	591:600	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	0	5	theme	Nanoparticle-filled	63:81	arg1	films					111:115	Nanoparticle-filled carrageenan-based composite films	63:115	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.	0:116	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	6	6	from	increase	970:977	arg1	8.0 mM					1022:1027	8.0 mM	1022:1027	8.0 mM	1022:1027	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	6	6	from	increase	970:977	arg1	pH					982:983	pH (2.0-12.0)	982:994	pH (2.0-12.0)	982:994	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	6	6	from	increase	970:977	arg1	concentration					1007:1019	ammonia concentration	999:1019	ammonia concentration (8.0 mM)	999:1028	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	1	7	theme	epigallocatechin	149:164	arg1	EGCG					175:178	EGCG	175:178	EGCG	175:178	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	1	7	theme	epigallocatechin	149:164	arg1	gallate					166:172	epigallocatechin gallate	149:172	epigallocatechin gallate (EGCG)	149:179	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	7	8	theme	free	1106:1109	arg1	scavenging					1119:1128	free radical scavenging	1106:1128	free radical scavenging activities	1106:1139	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36446506	5	9	theme	barrier	806:812	arg1	properties					884:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	1	10	theme	layer-by-layer	258:271	arg1	nanoparticles					273:285	curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles	220:285	curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles	220:285	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	0	11	theme	composite	101:109	arg1	films					111:115	Nanoparticle-filled carrageenan-based composite films	63:115	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.	0:116	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	3	12	theme	CZEC	558:561	arg1	nanoparticles					563:575	CZEC nanoparticles	558:575	CZEC nanoparticles	558:575	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	6	13	dep	increase	970:977	arg1	response					955:962	response	955:962	response	955:962	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	2	14	theme	smart	410:414	arg1	responses					416:424	smart responses	410:424	smart responses	410:424	These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses.					
36446506	8	15	theme	fish	1246:1249	arg1	freshness					1224:1232	the freshness	1220:1232	the freshness of packaged fish	1220:1249	Finally, the composite film exhibited the ability of monitoring and extending the freshness of packaged fish.					
36446506	5	16	theme	carrageenan	762:772	arg1	matrices					774:781	the carrageenan matrices	758:781	the carrageenan matrices	758:781	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	4	17	theme	films	681:685	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	2	18	theme	carrageenan	329:339	arg1	films					341:345	carrageenan films	329:345	carrageenan films	329:345	These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses.					
36446506	8	19	theme	composite	1155:1163	arg1	film					1165:1168	the composite film	1151:1168	the composite film	1151:1168	Finally, the composite film exhibited the ability of monitoring and extending the freshness of packaged fish.					
36446506	0	20	theme	novel	19:23	arg1	materials					52:60	a novel smart and active packaging materials	17:60	a novel smart and active packaging materials	17:60	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	5	21	theme	CZEC	707:710	arg1	nanoparticles					712:724	The CZEC nanoparticles	703:724	The CZEC nanoparticles	703:724	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	3	22	theme	nanoparticles	563:575	arg1	size					512:515	size	512:515	size	512:515	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	22	theme	nanoparticles	563:575	arg1	interactions					526:537	interactions	526:537	interactions	526:537	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	22	theme	nanoparticles	563:575	arg1	morphology					544:553	morphology	544:553	morphology	544:553	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	22	theme	nanoparticles	563:575	arg1	charge					518:523	charge	518:523	charge	518:523	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	6	23	theme	ammonia	999:1005	arg1	8.0 mM					1022:1027	8.0 mM	1022:1027	8.0 mM	1022:1027	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	6	23	theme	ammonia	999:1005	arg1	concentration					1007:1019	ammonia concentration	999:1019	ammonia concentration (8.0 mM)	999:1028	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	5	24	theme	mechanical	833:842	arg1	properties					884:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	4	25	theme	optical	582:588	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	3	26	used	used	487:490	arg2	micro-electrophoresis					445:465	micro-electrophoresis	445:465	micro-electrophoresis	445:465	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	26	used	used	487:490	arg2	scattering					433:442	Light scattering	427:442	Light scattering	427:442	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	26	used	used	487:490	arg2	SEM					478:480	SEM	478:480	SEM	478:480	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	3	26	used	used	487:490	arg2	FTIR					468:471	FTIR	468:471	FTIR	468:471	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	5	27	theme	7.09 	845:849	arg1	%					857:857	7.09 %-9.35 %	845:857	7.09 %-9.35 %	845:857	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	5	27	theme	7.09 	845:849	arg1	mechanical					833:842	mechanical	833:842	mechanical	833:842	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	8	28	theme	packaged	1237:1244	arg1	fish					1246:1249	packaged fish	1237:1249	packaged fish	1237:1249	Finally, the composite film exhibited the ability of monitoring and extending the freshness of packaged fish.					
36446506	5	29	theme	%	850:850	arg1	%					857:857	7.09 %-9.35 %	845:857	7.09 %-9.35 %	845:857	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	5	29	theme	%	850:850	arg1	mechanical					833:842	mechanical	833:842	mechanical	833:842	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	1	30	used	used	202:205	arg2	gallate					166:172	epigallocatechin gallate	149:172	epigallocatechin gallate (EGCG)	149:179	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	1	30	used	used	202:205	arg2	zein					143:146	zein	143:146	zein	143:146	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	1	30	used	used	202:205	arg2	curcumin					133:140	curcumin	133:140	curcumin	133:140	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	1	30	used	used	202:205	arg2	carrageenan					185:195	carrageenan	185:195	carrageenan	185:195	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	1	30	used	used	202:205	arg2	EGCG					175:178	EGCG	175:178	EGCG	175:178	In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles.					
36446506	4	31	theme	functional	652:661	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	0	32	theme	smart	25:29	arg1	materials					52:60	a novel smart and active packaging materials	17:60	a novel smart and active packaging materials	17:60	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	5	33	theme	UV	803:804	arg1	barrier					806:812	their UV barrier	797:812	their UV barrier (2.4-11.1 A mm-1)	797:830	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	5	33	theme	UV	803:804	arg1	2.4-11.1 A mm-1					815:829	2.4-11.1 A mm-1	815:829	2.4-11.1 A mm-1	815:829	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	4	34	theme	other	646:650	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	3	35	theme	Light	427:431	arg1	scattering					433:442	Light scattering	427:442	Light scattering	427:442	Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.					
36446506	0	36	theme	materials	52:60	arg1	Investigation					0:12	Investigation	0:12	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.	0:116	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	7	37	dep	DPPH	1072:1075	arg1	activities					1130:1139	free radical scavenging activities	1106:1139	free radical scavenging activities	1106:1139	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36446506	0	38	theme	active	35:40	arg1	materials					52:60	a novel smart and active packaging materials	17:60	a novel smart and active packaging materials	17:60	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	4	39	theme	morphological	603:615	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	2	40	theme	composite	355:363	arg1	films					365:369	composite films	355:369	composite films	355:369	These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses.					
36446506	6	41	theme	color	918:922	arg1	change					924:929	a color change	916:929	a color change	916:929	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	4	42	theme	spectroscopic	618:630	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	5	43	theme	resistance	873:882	arg1	properties					884:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties	797:893	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	6	44	dep	red	947:949	arg1	to					944:945	to	944:945	to	944:945	The films exhibited a color change, from yellow to red, in response to an increase in pH (2.0-12.0) or ammonia concentration (8.0 mM).					
36446506	5	45	theme	thermal	865:871	arg1	resistance					873:882	thermal resistance	865:882	thermal resistance	865:882	The CZEC nanoparticles were uniformly dispersed within the carrageenan matrices, and improved their UV barrier (2.4-11.1 A mm-1), mechanical (7.09 %-9.35 %), and thermal resistance properties.					
36446506	4	46	theme	thermal	633:639	arg1	attributes					663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes	578:672	attributes	663:672	The optical, mechanical, morphological, spectroscopic, thermal, and other functional attributes of the films were evaluated.					
36446506	0	47	theme	packaging	42:50	arg1	materials					52:60	a novel smart and active packaging materials	17:60	a novel smart and active packaging materials	17:60	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	0	48	dep	Investigation	0:12	arg1	films					111:115	Nanoparticle-filled carrageenan-based composite films	63:115	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.	0:116	Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.					
36446506	2	49	theme	antioxidant	385:395	arg1	activity					397:404	enhanced antioxidant activity	376:404	enhanced antioxidant activity	376:404	These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses.					
36446506	7	50	theme	radical	1111:1117	arg1	scavenging					1119:1128	free radical scavenging	1106:1128	free radical scavenging activities	1106:1139	The films also displayed relatively high DPPH (79.46 %) and ABTS (73.34 %) free radical scavenging activities.					
36682662	0	0	theme	hydrolysates	63:74	arg1	source					25:30	a new source	19:30	a new source of chitin/chitosan and protein hydrolysates	19:74	King crab gills as a new source of chitin/chitosan and protein hydrolysates.					
36682662	8	1	theme	gill	964:967	arg1	chitin					969:974	gill chitin	964:974	gill chitin	964:974	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	10	2	theme	crab	1219:1222	arg1	carapace					1224:1231	the crab carapace	1215:1231	the crab carapace	1215:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	0	3	theme	protein	55:61	arg1	hydrolysates					63:74	chitin/chitosan and protein hydrolysates	35:74	chitin/chitosan and protein hydrolysates	35:74	King crab gills as a new source of chitin/chitosan and protein hydrolysates.					
36682662	4	4	theme	first	477:481	arg1	time					483:486	the first time	473:486	the first time	473:486	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	9	5	theme	chitin	1087:1092	arg1	source					1077:1082	an additional source	1063:1082	an additional source of chitin in the integrated processing of king crabs	1063:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	9	5	theme	chitin	1087:1092	arg1	gills					1042:1046	Crab gills	1037:1046	Crab gills	1037:1046	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	1	6	theme	chitin	139:144	arg1	properties					125:134	the physicochemical properties	105:134	the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus	105:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	9	7	used	used	1055:1058	arg2	gills					1042:1046	Crab gills	1037:1046	Crab gills	1037:1046	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	9	7	used	used	1055:1058	arg2	source					1077:1082	an additional source	1063:1082	an additional source of chitin in the integrated processing of king crabs	1063:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	5	8	theme	crab	595:598	arg1	gills					600:604	crab gills	595:604	crab gills	595:604	Chitin was isolated from crab gills using chemical and enzymatic methods.					
36682662	8	9	theme	deacetylation	906:918	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	9	theme	deacetylation	906:918	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	9	theme	deacetylation	906:918	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	9	theme	deacetylation	906:918	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	10	10	theme	chitin	1151:1156	arg1	yield					1142:1146	The yield	1138:1146	The yield of chitin from the gills	1138:1171	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	10	theme	chitin	1151:1156	arg1	%					1185:1185	up to 45 %	1176:1185	up to 45 % of the yield of chitin from the crab carapace	1176:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	10	theme	chitin	1151:1156	arg1	yield					1194:1198	the yield	1190:1198	the yield of chitin from the crab carapace	1190:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	8	11	theme	chitin	969:974	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	11	theme	chitin	969:974	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	11	theme	chitin	969:974	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	11	theme	chitin	969:974	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	11	theme	chitin	969:974	arg1	similar					1005:1011	similar	1005:1011	similar	1005:1011	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	2	12	theme	chemical	253:260	arg1	composition					262:272	the chemical composition	249:272	the chemical composition of red king crab gills	249:295	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	6	13	theme	physicochemical	648:662	arg1	properties					664:673	The physicochemical properties	644:673	The physicochemical properties of chitin and chitosan from the gills	644:711	The physicochemical properties of chitin and chitosan from the gills were investigated.					
36682662	9	14	theme	Crab	1037:1040	arg1	source					1077:1082	an additional source	1063:1082	an additional source of chitin in the integrated processing of king crabs	1063:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	9	14	theme	Crab	1037:1040	arg1	gills					1042:1046	Crab gills	1037:1046	Crab gills	1037:1046	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	3	15	theme	dry	457:459	arg1	matter					461:466	dry matter	457:466	dry matter	457:466	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	4	16	theme	chitosan	560:567	arg1	gills					493:497	the gills	489:497	the gills of the king crab	489:514	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	4	16	theme	chitosan	560:567	arg1	source					539:544	a source	537:544	a source of chitin and chitosan	537:567	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	9	17	from	source	1077:1082	arg1	processing					1112:1121	the integrated processing	1097:1121	the integrated processing of king crabs	1097:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	8	18	theme	chitosan	980:987	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	18	theme	chitosan	980:987	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	18	theme	chitosan	980:987	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	18	theme	chitosan	980:987	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	18	theme	chitosan	980:987	arg1	similar					1005:1011	similar	1005:1011	similar	1005:1011	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	19	theme	crystal	942:948	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	19	theme	crystal	942:948	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	10	20	from	%	1185:1185	arg1	carapace					1224:1231	the crab carapace	1215:1231	the crab carapace	1215:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	7	21	theme	infrared	746:753	arg1	spectroscopy					755:766	infrared spectroscopy	746:766	infrared spectroscopy	746:766	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	10	22	from	gills	1167:1171	arg1	yield					1142:1146	The yield	1138:1146	The yield of chitin from the gills	1138:1171	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	22	from	gills	1167:1171	arg1	%					1185:1185	up to 45 %	1176:1185	up to 45 % of the yield of chitin from the crab carapace	1176:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	22	from	gills	1167:1171	arg1	yield					1194:1198	the yield	1190:1198	the yield of chitin from the crab carapace	1190:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	2	23	theme	crab	286:289	arg1	gills					291:295	red king crab gills	277:295	red king crab gills	277:295	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	7	24	theme	chitin	798:803	arg1	α-chitin					848:855	α-chitin	848:855	α-chitin	848:855	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	7	24	theme	chitin	798:803	arg1	present					805:811	the chitin present	794:811	the chitin present in the gills	794:824	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	0	25	theme	King	0:3	arg1	crab					5:8	King crab	0:8	King crab	0:8	King crab gills as a new source of chitin/chitosan and protein hydrolysates.					
36682662	3	26	contain	contained	409:417	arg1	terms					448:452	terms	448:452	terms of dry matter	448:466	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	3	26	contain	contained	409:417	arg2	chitin					438:443	approximately 21 % chitin	419:443	approximately 21 % chitin	419:443	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	3	26	contain	contained	409:417	arg1	gills					403:407	The gills	399:407	The gills	399:407	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	3	26	contain	contained	409:417	arg2	gills					403:407	The gills	399:407	The gills	399:407	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	9	27	theme	king	1126:1129	arg1	crabs					1131:1135	king crabs	1126:1135	king crabs	1126:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	2	28	theme	king	281:284	arg1	gills					291:295	red king crab gills	277:295	red king crab gills	277:295	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	10	29	theme	yield	1194:1198	arg1	yield					1142:1146	The yield	1138:1146	The yield of chitin from the gills	1138:1171	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	29	theme	yield	1194:1198	arg1	%					1185:1185	up to 45 %	1176:1185	up to 45 % of the yield of chitin from the crab carapace	1176:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	29	theme	yield	1194:1198	arg1	yield					1194:1198	the yield	1190:1198	the yield of chitin from the crab carapace	1190:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	7	30	from	present	805:811	arg1	gills					820:824	the gills	816:824	the gills	816:824	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	1	31	from	report	95:100	arg1	properties					125:134	the physicochemical properties	105:134	the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus	105:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	2	32	theme	red	277:279	arg1	gills					291:295	red king crab gills	277:295	red king crab gills	277:295	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	10	33	from	carapace	1224:1231	arg1	yield					1142:1146	The yield	1138:1146	The yield of chitin from the gills	1138:1171	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	33	from	carapace	1224:1231	arg1	%					1185:1185	up to 45 %	1176:1185	up to 45 % of the yield of chitin from the crab carapace	1176:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	10	33	from	carapace	1224:1231	arg1	yield					1194:1198	the yield	1190:1198	the yield of chitin from the crab carapace	1190:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	9	34	theme	additional	1066:1075	arg1	source					1077:1082	an additional source	1063:1082	an additional source of chitin in the integrated processing of king crabs	1063:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	9	34	theme	additional	1066:1075	arg1	gills					1042:1046	Crab gills	1037:1046	Crab gills	1037:1046	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	4	35	theme	crab	511:514	arg1	gills					493:497	the gills	489:497	the gills of the king crab	489:514	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	4	35	theme	crab	511:514	arg1	source					539:544	a source	537:544	a source of chitin and chitosan	537:567	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	10	36	theme	chitin	1203:1208	arg1	yield					1194:1198	the yield	1190:1198	the yield of chitin from the crab carapace	1190:1231	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	7	37	theme	X-ray	772:776	arg1	analyses					784:791	X-ray phase analyses	772:791	X-ray phase analyses	772:791	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	1	38	theme	king	173:176	arg1	camtschaticus					196:208	the king crab Paralithodes camtschaticus	169:208	the king crab Paralithodes camtschaticus	169:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	0	39	theme	new	21:23	arg1	source					25:30	a new source	19:30	a new source of chitin/chitosan and protein hydrolysates	19:74	King crab gills as a new source of chitin/chitosan and protein hydrolysates.					
36682662	4	40	theme	king	506:509	arg1	crab					511:514	the king crab	502:514	the king crab	502:514	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	8	41	theme	crab	1025:1028	arg1	shell					1030:1034	crab shell	1025:1034	crab shell	1025:1034	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	1	42	theme	crab	178:181	arg1	camtschaticus					196:208	the king crab Paralithodes camtschaticus	169:208	the king crab Paralithodes camtschaticus	169:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	7	43	theme	phase	778:782	arg1	analyses					784:791	X-ray phase analyses	772:791	X-ray phase analyses	772:791	By performing infrared spectroscopy and X-ray phase analyses, the chitin present in the gills was established to be α-chitin.					
36682662	2	44	theme	protein	377:383	arg1	hydrolysates					385:396	enzymatic protein hydrolysates	367:396	enzymatic protein hydrolysates	367:396	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	8	45	theme	physical	862:869	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	45	theme	physical	862:869	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	45	theme	physical	862:869	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	45	theme	physical	862:869	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	45	theme	physical	862:869	arg1	similar					1005:1011	similar	1005:1011	similar	1005:1011	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	1	46	theme	Paralithodes	183:194	arg1	camtschaticus					196:208	the king crab Paralithodes camtschaticus	169:208	the king crab Paralithodes camtschaticus	169:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	8	47	dep	properties	884:893	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	47	dep	properties	884:893	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	47	dep	properties	884:893	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	47	dep	properties	884:893	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	1	48	theme	first	89:93	arg1	This					77:80	This	77:80	This	77:80	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	1	48	theme	first	89:93	arg1	report					95:100	the first report	85:100	the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus	85:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	5	49	theme	chemical	612:619	arg1	methods					635:641	chemical and enzymatic methods	612:641	chemical and enzymatic methods	612:641	Chitin was isolated from crab gills using chemical and enzymatic methods.					
36682662	8	50	theme	chemical	875:882	arg1	structure					950:958	crystal structure	942:958	crystal structure	942:958	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	50	theme	chemical	875:882	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	50	theme	chemical	875:882	arg1	degree					896:901	degree	896:901	degree of deacetylation	896:918	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	50	theme	chemical	875:882	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	50	theme	chemical	875:882	arg1	similar					1005:1011	similar	1005:1011	similar	1005:1011	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	3	51	theme	matter	461:466	arg1	terms					448:452	terms	448:452	terms of dry matter	448:466	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	9	52	theme	crabs	1131:1135	arg1	processing					1112:1121	the integrated processing	1097:1121	the integrated processing of king crabs	1097:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	1	53	theme	physicochemical	109:123	arg1	properties					125:134	the physicochemical properties	105:134	the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus	105:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	6	54	theme	chitosan	689:696	arg1	properties					664:673	The physicochemical properties	644:673	The physicochemical properties of chitin and chitosan from the gills	644:711	The physicochemical properties of chitin and chitosan from the gills were investigated.					
36682662	6	55	from	gills	707:711	arg1	properties					664:673	The physicochemical properties	644:673	The physicochemical properties of chitin and chitosan from the gills	644:711	The physicochemical properties of chitin and chitosan from the gills were investigated.					
36682662	5	56	attach	isolated	581:588	arg1	gills					600:604	crab gills	595:604	crab gills	595:604	Chitin was isolated from crab gills using chemical and enzymatic methods.					
36682662	5	56	attach	isolated	581:588	arg2	Chitin					570:575	Chitin	570:575	Chitin	570:575	Chitin was isolated from crab gills using chemical and enzymatic methods.					
36682662	1	57	theme	camtschaticus	196:208	arg1	gills					160:164	gills	160:164	gills of the king crab Paralithodes camtschaticus	160:208	This is the first report on the physicochemical properties of chitin obtained from gills of the king crab Paralithodes camtschaticus.					
36682662	5	58	theme	enzymatic	625:633	arg1	methods					635:641	chemical and enzymatic methods	612:641	chemical and enzymatic methods	612:641	Chitin was isolated from crab gills using chemical and enzymatic methods.					
36682662	3	59	dep	%	436:436	arg1	21 					433:435	21 	433:435	21 	433:435	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	2	60	theme	gills	291:295	arg1	composition					262:272	the chemical composition	249:272	the chemical composition of red king crab gills	249:295	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	9	61	theme	integrated	1101:1110	arg1	processing					1112:1121	the integrated processing	1097:1121	the integrated processing of king crabs	1097:1135	Crab gills can be used as an additional source of chitin in the integrated processing of king crabs.					
36682662	2	62	theme	enzymatic	367:375	arg1	hydrolysates					385:396	enzymatic protein hydrolysates	367:396	enzymatic protein hydrolysates	367:396	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	3	63	dep	chitin	438:443	arg1	%					436:436	%	436:436	%	436:436	The gills contained approximately 21 % chitin in terms of dry matter.					
36682662	6	64	theme	chitin	678:683	arg1	properties					664:673	The physicochemical properties	644:673	The physicochemical properties of chitin and chitosan from the gills	644:711	The physicochemical properties of chitin and chitosan from the gills were investigated.					
36682662	2	65	theme	processing	335:344	arg1	methods					312:318	methods	312:318	methods of its complex processing	312:344	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	8	66	theme	molecular	921:929	arg1	weight					931:936	molecular weight	921:936	molecular weight	921:936	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	8	66	theme	molecular	921:929	arg1	properties					884:893	The physical and chemical properties	858:893	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan	858:987	The physical and chemical properties (degree of deacetylation, molecular weight and crystal structure) of gill chitin and chitosan were absolutely similar to those of crab shell.					
36682662	0	67	theme	chitin/chitosan	35:49	arg1	hydrolysates					63:74	chitin/chitosan and protein hydrolysates	35:74	chitin/chitosan and protein hydrolysates	35:74	King crab gills as a new source of chitin/chitosan and protein hydrolysates.					
36682662	2	68	theme	present	218:224	arg1	study					226:230	the present study	214:230	the present study	214:230	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	10	69	dep	45 	1182:1184	arg1	to					1179:1180	to	1179:1180	to	1179:1180	The yield of chitin from the gills is up to 45 % of the yield of chitin from the crab carapace.					
36682662	2	70	theme	complex	327:333	arg1	processing					335:344	its complex processing	323:344	its complex processing	323:344	In the present study, we investigated the chemical composition of red king crab gills and considered methods of its complex processing to obtain chitin and enzymatic protein hydrolysates.					
36682662	4	71	theme	chitin	549:554	arg1	gills					493:497	the gills	489:497	the gills of the king crab	489:514	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36682662	4	71	theme	chitin	549:554	arg1	source					539:544	a source	537:544	a source of chitin and chitosan	537:567	For the first time, the gills of the king crab were investigated as a source of chitin and chitosan.					
36538223	2	0	theme	textile	444:450	arg1	dyes					452:455	organic textile dyes	436:455	organic textile dyes	436:455	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	7	1	theme	reaction	1132:1139	arg1	rate					1124:1127	the rate	1120:1127	the rate of reaction	1120:1139	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	1	theme	reaction	1132:1139	arg1	efficiency					1093:1102	The efficiency	1089:1102	The efficiency of catalyst	1089:1114	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	3	2	theme	material	718:725	arg1	properties					704:713	mechanical properties	693:713	mechanical properties of material	693:725	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	1	3	theme	vinyl	174:178	arg1	PVA					189:191	PVA	189:191	PVA	189:191	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	1	3	theme	vinyl	174:178	arg1	alcohol					180:186	poly vinyl alcohol	169:186	poly vinyl alcohol (PVA)	169:192	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	0	4	theme	photocatalytic	93:106	arg1	degradation					108:118	photocatalytic degradation	93:118	photocatalytic degradation of cationic dyes	93:135	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	10	5	theme	higher	1517:1522	arg1	stability					1524:1532	higher stability	1517:1532	higher stability	1517:1532	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	8	6	theme	span	1364:1367	arg1	1 h					1352:1354	1 h	1352:1354	1 h of time span	1352:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	10	7	from	deletion	1665:1672	arg1	water					1701:1705	waste water	1695:1705	waste water	1695:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	1	8	theme	alcohol	180:186	arg1	benefits					157:164	the benefits	153:164	the benefits of poly vinyl alcohol (PVA) and chitosan (CS)	153:210	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	8	9	theme	dyes	1331:1334	arg1	efficiency					1266:1275	The maximum efficiency	1254:1275	The maximum efficiency of catalyst	1254:1287	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	9	theme	dyes	1331:1334	arg1	dyes					1331:1334	dyes	1331:1334	dyes degraded within 1 h of time span	1331:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	9	theme	dyes	1331:1334	arg1	%					1326:1326	more than 95%	1314:1326	more than 95% of dyes degraded within 1 h of time span	1314:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	0	10	theme	cationic	123:130	arg1	dyes					132:135	cationic dyes	123:135	cationic dyes	123:135	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	3	11	theme	PVA/CS-MNP	506:515	arg1	membrane					517:524	The as-synthesized PVA/CS-MNP membrane	487:524	The as-synthesized PVA/CS-MNP membrane	487:524	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	10	12	theme	effective	1655:1663	arg1	deletion					1665:1672	distinctly effective deletion	1644:1672	distinctly effective deletion of organic dyes from waste water	1644:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	4	13	theme	waste	866:870	arg1	water					872:876	industrial waste water	855:876	industrial waste water	855:876	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	3	14	theme	mechanical	693:702	arg1	properties					704:713	mechanical properties	693:713	mechanical properties of material	693:725	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	10	15	theme	waste	1695:1699	arg1	water					1701:1705	waste water	1695:1705	waste water	1695:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	2	16	theme	aqueous	468:474	arg1	solutions					476:484	their aqueous solutions	462:484	their aqueous solutions	462:484	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	1	17	theme	simple	333:338	arg1	method					359:364	a simple and facile casting method	331:364	a simple and facile casting method	331:364	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	10	18	theme	production	1539:1548	arg1	efficiency					1566:1575	excellent efficiency	1556:1575	excellent efficiency to degrade dyes	1556:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	18	theme	production	1539:1548	arg1	recyclability					1603:1615	good recyclability	1598:1615	good recyclability	1598:1615	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	18	theme	production	1539:1548	arg1	material					1631:1638	promising material	1621:1638	promising material for distinctly effective deletion of organic dyes from waste water	1621:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	18	theme	production	1539:1548	arg1	cost					1550:1553	low production cost	1535:1553	low production cost	1535:1553	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	4	19	theme	cationic	749:756	arg1	methylene					764:772	methylene blue	764:777	methylene blue (MB)	764:782	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	19	theme	cationic	749:756	arg1	dyes					831:834	template dyes	822:834	template dyes	822:834	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	19	theme	cationic	749:756	arg1	dyes					758:761	Two cationic dyes	745:761	Two cationic dyes	745:761	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	19	theme	cationic	749:756	arg1	yellow					794:799	eosin yellow	788:799	eosin yellow (EY)	788:804	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	20	attach	removed	842:848	arg2	dyes					758:761	Two cationic dyes	745:761	Two cationic dyes	745:761	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	20	attach	removed	842:848	arg2	dyes					831:834	template dyes	822:834	template dyes	822:834	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	20	attach	removed	842:848	arg1	water					872:876	industrial waste water	855:876	industrial waste water	855:876	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	20	attach	removed	842:848	arg2	yellow					794:799	eosin yellow	788:799	eosin yellow (EY)	788:804	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	20	attach	removed	842:848	arg2	methylene					764:772	methylene blue	764:777	methylene blue (MB)	764:782	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	0	21	theme	dyes	132:135	arg1	degradation					108:118	photocatalytic degradation	93:118	photocatalytic degradation of cationic dyes	93:135	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	2	22	theme	organic	436:442	arg1	dyes					452:455	organic textile dyes	436:455	organic textile dyes	436:455	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	4	23	theme	eosin	788:792	arg1	dyes					758:761	Two cationic dyes	745:761	Two cationic dyes	745:761	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	23	theme	eosin	788:792	arg1	EY					802:803	EY	802:803	EY	802:803	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	23	theme	eosin	788:792	arg1	yellow					794:799	eosin yellow	788:799	eosin yellow (EY)	788:804	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	3	24	theme	as-synthesized	491:504	arg1	membrane					517:524	The as-synthesized PVA/CS-MNP membrane	487:524	The as-synthesized PVA/CS-MNP membrane	487:524	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	7	25	theme	membrane	1244:1251	arg1	pH					1190:1191	pH	1190:1191	pH	1190:1191	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	25	theme	membrane	1244:1251	arg1	concentration					1202:1214	initial concentration	1194:1214	initial concentration of dyes	1194:1222	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	25	theme	membrane	1244:1251	arg1	composition					1229:1239	composition	1229:1239	composition of membrane	1229:1251	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	0	26	theme	PVA/chitosan	6:17	arg1	membrane					29:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	1	27	theme	facile	344:349	arg1	method					359:364	a simple and facile casting method	331:364	a simple and facile casting method	331:364	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	8	28	theme	catalyst	1280:1287	arg1	efficiency					1266:1275	The maximum efficiency	1254:1275	The maximum efficiency of catalyst	1254:1287	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	28	theme	catalyst	1280:1287	arg1	dyes					1331:1334	dyes	1331:1334	dyes degraded within 1 h of time span	1331:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	28	theme	catalyst	1280:1287	arg1	%					1326:1326	more than 95%	1314:1326	more than 95% of dyes degraded within 1 h of time span	1314:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	0	29	theme	Novel	0:4	arg1	membrane					29:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	1	30	theme	novel	248:252	arg1	type					254:257	a novel type	246:257	a novel type of nano-polymer composite (PVA/CS-MNP) membrane	246:305	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	3	31	theme	emission	642:649	arg1	FESEM					681:685	FESEM	681:685	FESEM	681:685	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	31	theme	emission	642:649	arg1	microscopy					669:678	field emission scanning electron microscopy	636:678	field emission scanning electron microscopy (FESEM)	636:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	32	theme	different	545:553	arg1	techniques					566:575	different analytical techniques	545:575	different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	545:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	32	theme	different	545:553	arg1	Fourier					585:591	Fourier	585:591	Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	585:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	5	33	used	used	969:972	arg2	membrane					956:963	the synthesized membrane	940:963	the synthesized membrane	940:963	These dyes were degraded by carrying out a reaction in which the synthesized membrane was used as a photocatalyst.					
36538223	5	33	used	used	969:972	arg2	photocatalyst					979:991	a photocatalyst	977:991	a photocatalyst	977:991	These dyes were degraded by carrying out a reaction in which the synthesized membrane was used as a photocatalyst.					
36538223	9	34	theme	several	1470:1476	arg1	times					1478:1482	several times	1470:1482	several times	1470:1482	The catalyst was found to be reusable as its efficiency did not deteriorate even after using it for several times.					
36538223	6	35	theme	pseudo-first-order	1060:1077	arg1	kinetics					1079:1086	pseudo-first-order kinetics	1060:1086	pseudo-first-order kinetics	1060:1086	The study of kinetics revealed that the reaction process followed pseudo-first-order kinetics.					
36538223	1	36	theme	chitosan	198:205	arg1	benefits					157:164	the benefits	153:164	the benefits of poly vinyl alcohol (PVA) and chitosan (CS)	153:210	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	0	37	theme	composite	19:27	arg1	membrane					29:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane	0:36	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	10	38	theme	good	1598:1601	arg1	efficiency					1566:1575	excellent efficiency	1556:1575	excellent efficiency to degrade dyes	1556:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	38	theme	good	1598:1601	arg1	recyclability					1603:1615	good recyclability	1598:1615	good recyclability	1598:1615	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	38	theme	good	1598:1601	arg1	material					1631:1638	promising material	1621:1638	promising material for distinctly effective deletion of organic dyes from waste water	1621:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	38	theme	good	1598:1601	arg1	cost					1550:1553	low production cost	1535:1553	low production cost	1535:1553	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	1	39	theme	casting	351:357	arg1	method					359:364	a simple and facile casting method	331:364	a simple and facile casting method	331:364	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	10	40	theme	degrade	1580:1586	arg1	dyes					1588:1591	degrade dyes	1580:1591	degrade dyes	1580:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	8	41	theme	time	1359:1362	arg1	span					1364:1367	time span	1359:1367	time span	1359:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	3	42	dep	transform	593:601	arg1	infrared					603:610	infrared	603:610	transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	593:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	10	43	theme	functional	1490:1499	arg1	membrane					1501:1508	Such functional membrane	1485:1508	Such functional membrane	1485:1508	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	1	44	theme	nano-polymer	262:273	arg1	membrane					298:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	4	45	theme	industrial	855:864	arg1	water					872:876	industrial waste water	855:876	industrial waste water	855:876	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	7	46	theme	catalyst	1107:1114	arg1	rate					1124:1127	the rate	1120:1127	the rate of reaction	1120:1139	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	46	theme	catalyst	1107:1114	arg1	efficiency					1093:1102	The efficiency	1089:1102	The efficiency of catalyst	1089:1114	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	10	47	theme	dyes	1685:1688	arg1	deletion					1665:1672	distinctly effective deletion	1644:1672	distinctly effective deletion of organic dyes from waste water	1644:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	48	from	water	1701:1705	arg1	deletion					1665:1672	distinctly effective deletion	1644:1672	distinctly effective deletion of organic dyes from waste water	1644:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	48	from	water	1701:1705	arg1	dyes					1685:1688	organic dyes	1677:1688	organic dyes from waste water	1677:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	2	49	theme	proposed	375:382	arg1	work					384:387	this proposed work	370:387	this proposed work	370:387	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	10	50	theme	Such	1485:1488	arg1	membrane					1501:1508	Such functional membrane	1485:1508	Such functional membrane	1485:1508	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	1	51	theme	composite	275:283	arg1	membrane					298:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	10	52	theme	organic	1677:1683	arg1	dyes					1685:1688	organic dyes	1677:1688	organic dyes from waste water	1677:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	8	53	located	observed	1293:1300	arg2	%					1326:1326	more than 95%	1314:1326	more than 95% of dyes degraded within 1 h of time span	1314:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	53	located	observed	1293:1300	arg2	efficiency					1266:1275	The maximum efficiency	1254:1275	The maximum efficiency of catalyst	1254:1287	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	53	located	observed	1293:1300	arg1	pH					1305:1306	pH 12	1305:1309	pH 12	1305:1309	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	53	located	observed	1293:1300	arg2	dyes					1331:1334	dyes	1331:1334	dyes degraded within 1 h of time span	1331:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	0	54	theme	α-MnO2	68:73	arg1	nanoparticles					75:87	bio-fabricated α-MnO2 nanoparticles	53:87	bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes	53:135	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	4	55	theme	template	822:829	arg1	dyes					831:834	template dyes	822:834	template dyes	822:834	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	55	theme	template	822:829	arg1	dyes					758:761	Two cationic dyes	745:761	Two cationic dyes	745:761	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	3	56	theme	analytical	555:564	arg1	techniques					566:575	different analytical techniques	545:575	different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	545:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	56	theme	analytical	555:564	arg1	Fourier					585:591	Fourier	585:591	Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	585:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	0	57	theme	bio-fabricated	53:66	arg1	nanoparticles					75:87	bio-fabricated α-MnO2 nanoparticles	53:87	bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes	53:135	Novel PVA/chitosan composite membrane modified using bio-fabricated α-MnO2 nanoparticles for photocatalytic degradation of cationic dyes.					
36538223	1	58	theme	PVA/CS-MNP	286:295	arg1	membrane					298:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	nano-polymer composite (PVA/CS-MNP) membrane	262:305	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	1	59	theme	membrane	298:305	arg1	type					254:257	a novel type	246:257	a novel type of nano-polymer composite (PVA/CS-MNP) membrane	246:305	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	3	60	theme	scanning	651:658	arg1	FESEM					681:685	FESEM	681:685	FESEM	681:685	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	60	theme	scanning	651:658	arg1	microscopy					669:678	field emission scanning electron microscopy	636:678	field emission scanning electron microscopy (FESEM)	636:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	5	61	theme	synthesized	944:954	arg1	photocatalyst					979:991	a photocatalyst	977:991	a photocatalyst	977:991	These dyes were degraded by carrying out a reaction in which the synthesized membrane was used as a photocatalyst.					
36538223	5	61	theme	synthesized	944:954	arg1	membrane					956:963	the synthesized membrane	940:963	the synthesized membrane	940:963	These dyes were degraded by carrying out a reaction in which the synthesized membrane was used as a photocatalyst.					
36538223	6	62	theme	reaction	1034:1041	arg1	process					1043:1049	the reaction process	1030:1049	the reaction process	1030:1049	The study of kinetics revealed that the reaction process followed pseudo-first-order kinetics.					
36538223	3	63	theme	electron	660:667	arg1	FESEM					681:685	FESEM	681:685	FESEM	681:685	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	63	theme	electron	660:667	arg1	microscopy					669:678	field emission scanning electron microscopy	636:678	field emission scanning electron microscopy (FESEM)	636:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	10	64	theme	low	1535:1537	arg1	efficiency					1566:1575	excellent efficiency	1556:1575	excellent efficiency to degrade dyes	1556:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	64	theme	low	1535:1537	arg1	recyclability					1603:1615	good recyclability	1598:1615	good recyclability	1598:1615	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	64	theme	low	1535:1537	arg1	material					1631:1638	promising material	1621:1638	promising material for distinctly effective deletion of organic dyes from waste water	1621:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	64	theme	low	1535:1537	arg1	cost					1550:1553	low production cost	1535:1553	low production cost	1535:1553	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	65	theme	excellent	1556:1564	arg1	efficiency					1566:1575	excellent efficiency	1556:1575	excellent efficiency to degrade dyes	1556:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	65	theme	excellent	1556:1564	arg1	recyclability					1603:1615	good recyclability	1598:1615	good recyclability	1598:1615	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	65	theme	excellent	1556:1564	arg1	material					1631:1638	promising material	1621:1638	promising material for distinctly effective deletion of organic dyes from waste water	1621:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	65	theme	excellent	1556:1564	arg1	cost					1550:1553	low production cost	1535:1553	low production cost	1535:1553	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	8	66	theme	maximum	1258:1264	arg1	efficiency					1266:1275	The maximum efficiency	1254:1275	The maximum efficiency of catalyst	1254:1287	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	66	theme	maximum	1258:1264	arg1	dyes					1331:1334	dyes	1331:1334	dyes degraded within 1 h of time span	1331:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	8	66	theme	maximum	1258:1264	arg1	%					1326:1326	more than 95%	1314:1326	more than 95% of dyes degraded within 1 h of time span	1314:1367	The maximum efficiency of catalyst was observed at pH 12 as more than 95% of dyes degraded within 1 h of time span.					
36538223	3	67	theme	field	636:640	arg1	FESEM					681:685	FESEM	681:685	FESEM	681:685	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	3	67	theme	field	636:640	arg1	microscopy					669:678	field emission scanning electron microscopy	636:678	field emission scanning electron microscopy (FESEM)	636:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	10	68	theme	promising	1621:1629	arg1	efficiency					1566:1575	excellent efficiency	1556:1575	excellent efficiency to degrade dyes	1556:1591	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	68	theme	promising	1621:1629	arg1	recyclability					1603:1615	good recyclability	1598:1615	good recyclability	1598:1615	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	68	theme	promising	1621:1629	arg1	material					1631:1638	promising material	1621:1638	promising material for distinctly effective deletion of organic dyes from waste water	1621:1705	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	10	68	theme	promising	1621:1629	arg1	cost					1550:1553	low production cost	1535:1553	low production cost	1535:1553	Such functional membrane having higher stability, low production cost, excellent efficiency to degrade dyes, and good recyclability are promising material for distinctly effective deletion of organic dyes from waste water.					
36538223	6	69	theme	kinetics	1007:1014	arg1	study					998:1002	The study	994:1002	The study of kinetics	994:1014	The study of kinetics revealed that the reaction process followed pseudo-first-order kinetics.					
36538223	1	70	theme	α-MnO2	217:222	arg1	nanoparticles					224:236	α-MnO2 nanoparticles	217:236	α-MnO2 nanoparticles (MNPs)	217:243	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	1	70	theme	α-MnO2	217:222	arg1	MNPs					239:242	MNPs	239:242	MNPs	239:242	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	2	71	from	solutions	476:484	arg1	removal					425:431	removal	425:431	removal of organic textile dyes from their aqueous solutions	425:484	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	4	72	theme	blue	774:777	arg1	methylene					764:772	methylene blue	764:777	methylene blue (MB)	764:782	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	72	theme	blue	774:777	arg1	MB					780:781	MB	780:781	MB	780:781	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	4	72	theme	blue	774:777	arg1	dyes					758:761	Two cationic dyes	745:761	Two cationic dyes	745:761	Two cationic dyes, methylene blue (MB) and eosin yellow (EY), were chosen as template dyes to be removed from industrial waste water.					
36538223	3	73	dep	Fourier	585:591	arg1	transform					593:601	transform	593:601	transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)	593:686	The as-synthesized PVA/CS-MNP membrane was examined using different analytical techniques such as Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM), and mechanical properties of material was also studied.					
36538223	7	74	theme	dyes	1219:1222	arg1	pH					1190:1191	pH	1190:1191	pH	1190:1191	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	74	theme	dyes	1219:1222	arg1	concentration					1202:1214	initial concentration	1194:1214	initial concentration of dyes	1194:1222	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	7	74	theme	dyes	1219:1222	arg1	composition					1229:1239	composition	1229:1239	composition of membrane	1229:1251	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	2	75	theme	dyes	452:455	arg1	removal					425:431	removal	425:431	removal of organic textile dyes from their aqueous solutions	425:484	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	2	76	used	used	416:419	arg2	membrane					394:401	the membrane	390:401	the membrane prepared	390:410	In this proposed work, the membrane prepared was used for removal of organic textile dyes from their aqueous solutions.					
36538223	7	77	theme	initial	1194:1200	arg1	concentration					1202:1214	initial concentration	1194:1214	initial concentration of dyes	1194:1222	The efficiency of catalyst and the rate of reaction were also examined by varying parameters such as pH, initial concentration of dyes, and composition of membrane.					
36538223	1	78	theme	poly	169:172	arg1	PVA					189:191	PVA	189:191	PVA	189:191	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
36538223	1	78	theme	poly	169:172	arg1	alcohol					180:186	poly vinyl alcohol	169:186	poly vinyl alcohol (PVA)	169:192	By integrating the benefits of poly vinyl alcohol (PVA) and chitosan (CS) with α-MnO2 nanoparticles (MNPs), a novel type of nano-polymer composite (PVA/CS-MNP) membrane was synthesized through a simple and facile casting method.					
35209056	2	0	theme	rheology	354:361	arg1	characteristics					363:377	rheology characteristics	354:377	rheology characteristics	354:377	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	4	1	theme	antioxidant	644:654	arg1	activity					605:612	Antioxidant activity	593:612	Antioxidant activity	593:612	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	4	1	theme	antioxidant	644:654	arg1	activity					656:663	the total antioxidant activity	634:663	the total antioxidant activity	634:663	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	11	2	theme	power	1661:1665	arg1	activity					1667:1674	reducing power activity	1652:1674	reducing power activity	1652:1674	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	6	3	theme	function	887:894	arg1	groups					896:901	function groups	887:901	function groups	887:901	Physic-chemistry characterization was determined, including the molecular weight, sugar composition, function groups, and crystal structure, through GCP, GC-FID, FTIR, and XRD.					
35209056	3	4	theme	Box-Behken	581:590	arg1	method					544:549	the maceration-stirred method	521:549	the maceration-stirred method	521:549	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	3	4	theme	Box-Behken	581:590	arg1	model					572:576	the experimental model	555:576	the experimental model of Box-Behken	555:590	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	13	5	from	use	1939:1941	arg1	food					1946:1949	food	1946:1949	food	1946:1949	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	13	5	from	use	1939:1941	arg1	pharmaceuticals					1955:1969	pharmaceuticals	1955:1969	pharmaceuticals	1955:1969	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	11	6	theme	mg	1760:1761	arg1	DW					1782:1783	mg FeSO4 equivalent/g DW	1760:1783	mg FeSO4 equivalent/g DW	1760:1783	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	6	theme	mg	1760:1761	arg1	±					1752:1752	89.84 ± 5.84	1746:1757	89.84 ± 5.84 (mg FeSO4 equivalent/g DW)	1746:1784	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	5	7	theme	rheology	698:705	arg1	strength					762:769	gel strength	758:769	gel strength	758:769	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	5	7	theme	rheology	698:705	arg1	characteristics					707:721	The rheology characteristics	694:721	The rheology characteristics of carrageenan	694:736	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	11	8	theme	carrageenan	1567:1577	arg1	efficiency					1553:1562	the extraction efficiency	1538:1562	the extraction efficiency of carrageenan	1538:1577	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	8	theme	carrageenan	1567:1577	arg1	±					1605:1605	87.56 ± 5.61	1599:1610	87.56 ± 5.61 (%)	1599:1614	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	8	9	theme	weight	1238:1243	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	0	10	theme	Physicochemistry	109:124	arg1	Characterization					126:141	Physicochemistry Characterization	109:141	Physicochemistry Characterization	109:141	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	1	11	theme	high	214:217	arg1	content					219:225	a high content	212:225	a high content of red seaweed Eucheuma gelatinae	212:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	12	12	dep	%	1867:1867	arg1	DW					1870:1871	DW	1870:1871	DW	1870:1871	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	8	13	theme	×	1264:1264	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	11	14	theme	equivalent/g	1769:1780	arg1	DW					1782:1783	mg FeSO4 equivalent/g DW	1760:1783	mg FeSO4 equivalent/g DW	1760:1783	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	14	theme	equivalent/g	1769:1780	arg1	±					1752:1752	89.84 ± 5.84	1746:1757	89.84 ± 5.84 (mg FeSO4 equivalent/g DW)	1746:1784	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	13	15	dep	Eucheuma	1904:1911	arg1	gelatinae					1913:1921	Eucheuma gelatinae	1904:1921	Eucheuma gelatinae	1904:1921	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	11	16	theme	equivalent/g	1725:1736	arg1	DW					1738:1739	mg ascorbic acid equivalent/g DW	1708:1739	mg ascorbic acid equivalent/g DW	1708:1739	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	16	theme	equivalent/g	1725:1736	arg1	±					1700:1700	71.95 ± 5.32	1694:1705	71.95 ± 5.32 (mg ascorbic acid equivalent/g DW)	1694:1740	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	5	17	theme	gel	758:760	arg1	characteristics					707:721	The rheology characteristics	694:721	The rheology characteristics of carrageenan	694:736	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	5	17	theme	gel	758:760	arg1	strength					762:769	gel strength	758:769	gel strength	758:769	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	11	18	theme	ascorbic	1711:1718	arg1	DW					1738:1739	mg ascorbic acid equivalent/g DW	1708:1739	mg ascorbic acid equivalent/g DW	1708:1739	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	18	theme	ascorbic	1711:1718	arg1	±					1700:1700	71.95 ± 5.32	1694:1705	71.95 ± 5.32 (mg ascorbic acid equivalent/g DW)	1694:1740	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	7	19	theme	intrinsic	1035:1043	arg1	viscosity					1045:1053	intrinsic viscosity	1035:1053	intrinsic viscosity	1035:1053	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	10	20	theme	solvent-to-algae	1468:1483	arg1	ratio					1485:1489	a solvent-to-algae ratio	1466:1489	a solvent-to-algae ratio of 36.42 (v/w)	1466:1504	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	11	21	theme	89.84	1746:1750	arg1	DW					1782:1783	mg FeSO4 equivalent/g DW	1760:1783	mg FeSO4 equivalent/g DW	1760:1783	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	21	theme	89.84	1746:1750	arg1	±					1752:1752	89.84 ± 5.84	1746:1757	89.84 ± 5.84 (mg FeSO4 equivalent/g DW)	1746:1784	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	1	22	theme	sulfated	170:177	arg1	polysaccharide					179:192	an anionic sulfated polysaccharide	159:192	an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae	159:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	1	22	theme	sulfated	170:177	arg1	Carrageenan					144:154	Carrageenan	144:154	Carrageenan	144:154	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	7	23	dep	possessed	999:1007	arg1	had					1031:1033	had	1031:1033	had intrinsic viscosity and gel strength	1031:1070	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	0	24	theme	Rheology	79:86	arg1	Characteristics					88:102	Rheology Characteristics	79:102	Rheology Characteristics	79:102	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	7	25	theme	antioxidant	1009:1019	arg1	activity					1021:1028	antioxidant activity	1009:1028	antioxidant activity	1009:1028	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	2	26	theme	β-carrageenan	421:433	arg1	extraction					288:297	extraction	288:297	extraction	288:297	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	26	theme	β-carrageenan	421:433	arg1	characteristics					363:377	rheology characteristics	354:377	rheology characteristics	354:377	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	26	theme	β-carrageenan	421:433	arg1	characterization					401:416	physic-chemistry characterization	384:416	physic-chemistry characterization of β-carrageenan	384:433	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	26	theme	β-carrageenan	421:433	arg1	optimization					300:311	optimization	300:311	optimization	300:311	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	26	theme	β-carrageenan	421:433	arg1	evaluation					318:327	evaluation	318:327	evaluation of antioxidant activity	318:351	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	8	27	with	xylose	1211:1216	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	12	28	theme	42.68	1853:1857	arg1	±					1859:1859	42.68 ± 2.37	1853:1864	42.68 ± 2.37 (%, DW)	1853:1872	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	12	28	theme	42.68	1853:1857	arg1	%					1867:1867	%	1867:1867	%	1867:1867	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	8	29	dep	×	1264:1264	arg1	g/mol					1285:1289	g/mol	1285:1289	g/mol	1285:1289	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	11	30	theme	extraction	1542:1551	arg1	efficiency					1553:1562	the extraction efficiency	1538:1562	the extraction efficiency of carrageenan	1538:1577	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	30	theme	extraction	1542:1551	arg1	±					1605:1605	87.56 ± 5.61	1599:1610	87.56 ± 5.61 (%)	1599:1614	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	3	31	theme	β-carrageenan	499:511	arg1	extraction					464:473	The extraction	460:473	The extraction	460:473	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	3	31	theme	β-carrageenan	499:511	arg1	optimization					483:494	the optimization	479:494	the optimization of β-carrageenan	479:511	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	0	32	theme	Red	15:17	arg1	Algae					19:23	Red Algae	15:23	Red Algae	15:23	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	8	33	theme	Antioxidant	1132:1142	arg1	carrageenan					1144:1154	Antioxidant carrageenan	1132:1154	Antioxidant carrageenan	1132:1154	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	11	34	theme	71.95	1694:1698	arg1	DW					1738:1739	mg ascorbic acid equivalent/g DW	1708:1739	mg ascorbic acid equivalent/g DW	1708:1739	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	34	theme	71.95	1694:1698	arg1	±					1700:1700	71.95 ± 5.32	1694:1705	71.95 ± 5.32 (mg ascorbic acid equivalent/g DW)	1694:1740	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	2	35	dep	Eucheuma	440:447	arg1	gelatinae					449:457	Eucheuma gelatinae	440:457	Eucheuma gelatinae	440:457	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	3	36	theme	maceration-stirred	525:542	arg1	method					544:549	the maceration-stirred method	521:549	the maceration-stirred method	521:549	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	11	37	theme	mg	1708:1709	arg1	DW					1738:1739	mg ascorbic acid equivalent/g DW	1708:1739	mg ascorbic acid equivalent/g DW	1708:1739	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	37	theme	mg	1708:1709	arg1	±					1700:1700	71.95 ± 5.32	1694:1705	71.95 ± 5.32 (mg ascorbic acid equivalent/g DW)	1694:1740	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	38	theme	87.56	1599:1603	arg1	±					1605:1605	87.56 ± 5.61	1599:1610	87.56 ± 5.61 (%)	1599:1614	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	38	theme	87.56	1599:1603	arg1	%					1613:1613	%	1613:1613	%	1613:1613	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	38	theme	87.56	1599:1603	arg1	efficiency					1553:1562	the extraction efficiency	1538:1562	the extraction efficiency of carrageenan	1538:1577	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	2	39	theme	antioxidant	332:342	arg1	activity					344:351	antioxidant activity	332:351	antioxidant activity	332:351	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	1	40	theme	red	230:232	arg1	gelatinae					251:259	red seaweed Eucheuma gelatinae	230:259	red seaweed Eucheuma gelatinae	230:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	12	41	theme	Purity	1801:1806	arg1	content					1820:1826	Purity carrageenan content	1801:1826	Purity carrageenan content	1801:1826	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	6	42	theme	crystal	908:914	arg1	structure					916:924	crystal structure	908:924	crystal structure	908:924	Physic-chemistry characterization was determined, including the molecular weight, sugar composition, function groups, and crystal structure, through GCP, GC-FID, FTIR, and XRD.					
35209056	10	43	theme	optimization	1364:1375	arg1	condition					1377:1385	The optimization condition	1360:1385	The optimization condition of antioxidant carrageenan extraction	1360:1423	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	2	44	from	Eucheuma	440:447	arg1	extraction					288:297	extraction	288:297	extraction	288:297	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	44	from	Eucheuma	440:447	arg1	characteristics					363:377	rheology characteristics	354:377	rheology characteristics	354:377	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	44	from	Eucheuma	440:447	arg1	characterization					401:416	physic-chemistry characterization	384:416	physic-chemistry characterization of β-carrageenan	384:433	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	44	from	Eucheuma	440:447	arg1	optimization					300:311	optimization	300:311	optimization	300:311	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	44	from	Eucheuma	440:447	arg1	evaluation					318:327	evaluation	318:327	evaluation of antioxidant activity	318:351	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	10	45	theme	antioxidant	1390:1400	arg1	extraction					1414:1423	antioxidant carrageenan extraction	1390:1423	antioxidant carrageenan extraction	1390:1423	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	3	46	theme	experimental	559:570	arg1	model					572:576	the experimental model	555:576	the experimental model of Box-Behken	555:590	The extraction and the optimization of β-carrageenan were by the maceration-stirred method and the experimental model of Box-Behken.					
35209056	1	47	theme	Eucheuma	242:249	arg1	gelatinae					251:259	red seaweed Eucheuma gelatinae	230:259	red seaweed Eucheuma gelatinae	230:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	8	48	with	mannose	1181:1187	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	4	49	theme	reducing	669:676	arg1	activity					684:691	reducing power activity	669:691	reducing power activity	669:691	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	6	50	theme	Physic-chemistry	786:801	arg1	characterization					803:818	Physic-chemistry characterization	786:818	Physic-chemistry characterization	786:818	Physic-chemistry characterization was determined, including the molecular weight, sugar composition, function groups, and crystal structure, through GCP, GC-FID, FTIR, and XRD.					
35209056	11	51	theme	total	1621:1625	arg1	activity					1639:1646	the total antioxidant activity	1617:1646	the total antioxidant activity	1617:1646	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	5	52	theme	carrageenan	726:736	arg1	strength					762:769	gel strength	758:769	gel strength	758:769	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	5	52	theme	carrageenan	726:736	arg1	characteristics					707:721	The rheology characteristics	694:721	The rheology characteristics of carrageenan	694:736	The rheology characteristics of carrageenan were measured to be gel strength and viscosity.					
35209056	4	53	theme	total	638:642	arg1	activity					605:612	Antioxidant activity	593:612	Antioxidant activity	593:612	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	4	53	theme	total	638:642	arg1	activity					656:663	the total antioxidant activity	634:663	the total antioxidant activity	634:663	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	10	54	theme	extraction	1414:1423	arg1	condition					1377:1385	The optimization condition	1360:1385	The optimization condition of antioxidant carrageenan extraction	1360:1423	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	11	55	theme	reducing	1652:1659	arg1	activity					1667:1674	reducing power activity	1652:1674	reducing power activity	1652:1674	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	6	56	theme	sugar	868:872	arg1	composition					874:884	sugar composition	868:884	sugar composition	868:884	Physic-chemistry characterization was determined, including the molecular weight, sugar composition, function groups, and crystal structure, through GCP, GC-FID, FTIR, and XRD.					
35209056	7	57	contain	possessed	999:1007	arg1	carrageenan					987:997	carrageenan	987:997	carrageenan	987:997	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	7	57	contain	possessed	999:1007	arg2	activity					1021:1028	antioxidant activity	1009:1028	antioxidant activity	1009:1028	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	11	58	theme	FeSO4	1763:1767	arg1	DW					1782:1783	mg FeSO4 equivalent/g DW	1760:1783	mg FeSO4 equivalent/g DW	1760:1783	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	58	theme	FeSO4	1763:1767	arg1	±					1752:1752	89.84 ± 5.84	1746:1757	89.84 ± 5.84 (mg FeSO4 equivalent/g DW)	1746:1784	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	13	59	theme	Antioxidant	1875:1885	arg1	carrageenan					1887:1897	Antioxidant carrageenan	1875:1897	Antioxidant carrageenan from Eucheuma gelatinae	1875:1921	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	8	60	theme	molecular	1228:1236	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	0	61	theme	Antioxidant	57:67	arg1	Activity					69:76	Antioxidant Activity	57:76	Antioxidant Activity	57:76	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	11	62	theme	optimization	1514:1525	arg1	condition					1527:1535	the optimization condition	1510:1535	the optimization condition	1510:1535	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	7	63	theme	gel	1059:1061	arg1	strength					1063:1070	gel strength	1059:1070	gel strength	1059:1070	The results showed that carrageenan possessed antioxidant activity, had intrinsic viscosity and gel strength, corresponding to 263.02 cps and 487.5 g/cm2, respectively.					
35209056	13	64	from	Eucheuma	1904:1911	arg1	carrageenan					1887:1897	Antioxidant carrageenan	1875:1897	Antioxidant carrageenan from Eucheuma gelatinae	1875:1921	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	11	65	theme	acid	1720:1723	arg1	DW					1738:1739	mg ascorbic acid equivalent/g DW	1708:1739	mg ascorbic acid equivalent/g DW	1708:1739	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	11	65	theme	acid	1720:1723	arg1	±					1700:1700	71.95 ± 5.32	1694:1705	71.95 ± 5.32 (mg ascorbic acid equivalent/g DW)	1694:1740	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	9	66	theme	Antioxidant	1306:1316	arg1	carrageenan					1318:1328	Antioxidant carrageenan	1306:1328	Antioxidant carrageenan	1306:1328	Antioxidant carrageenan did not exist in the crystal.					
35209056	1	67	theme	anionic	162:168	arg1	polysaccharide					179:192	an anionic sulfated polysaccharide	159:192	an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae	159:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	1	67	theme	anionic	162:168	arg1	Carrageenan					144:154	Carrageenan	144:154	Carrageenan	144:154	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	12	68	from	±	1859:1859	arg1	got					1828:1830	got	1828:1830	got	1828:1830	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	8	69	with	fucose	1199:1204	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	8	70	with	glucose	1190:1196	arg1	fractions					1245:1253	two molecular weight fractions	1224:1253	two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively	1224:1303	Antioxidant carrageenan is composed of rhamnose, mannose, glucose, fucose, and xylose, with two molecular weight fractions of 2.635 × 106 and 2.58 × 106 g/mol, respectively.					
35209056	10	71	with	min	1457:1459	arg1	ratio					1485:1489	a solvent-to-algae ratio	1466:1489	a solvent-to-algae ratio of 36.42 (v/w)	1466:1504	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	10	72	theme	36.42	1494:1498	arg1	ratio					1485:1489	a solvent-to-algae ratio	1466:1489	a solvent-to-algae ratio of 36.42 (v/w)	1466:1504	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	2	73	theme	physic-chemistry	384:399	arg1	characterization					401:416	physic-chemistry characterization	384:416	physic-chemistry characterization of β-carrageenan	384:433	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	0	74	theme	Algae	19:23	arg1	Carrageenan					0:10	Carrageenan	0:10	Carrageenan of Red Algae	0:23	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	12	75	theme	highest	1836:1842	arg1	value					1844:1848	the highest value	1832:1848	the highest value	1832:1848	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	6	76	theme	molecular	850:858	arg1	weight					860:865	the molecular weight	846:865	the molecular weight	846:865	Physic-chemistry characterization was determined, including the molecular weight, sugar composition, function groups, and crystal structure, through GCP, GC-FID, FTIR, and XRD.					
35209056	0	77	dep	gelatinae	34:42	arg1	Activity					69:76	Antioxidant Activity	57:76	Antioxidant Activity	57:76	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	0	77	dep	gelatinae	34:42	arg1	Characteristics					88:102	Rheology Characteristics	79:102	Rheology Characteristics	79:102	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	0	77	dep	gelatinae	34:42	arg1	Carrageenan					0:10	Carrageenan	0:10	Carrageenan of Red Algae	0:23	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	0	77	dep	gelatinae	34:42	arg1	Characterization					126:141	Physicochemistry Characterization	109:141	Physicochemistry Characterization	109:141	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	0	77	dep	gelatinae	34:42	arg1	Extraction					45:54	Extraction	45:54	Extraction	45:54	Carrageenan of Red Algae Eucheuma gelatinae: Extraction, Antioxidant Activity, Rheology Characteristics, and Physicochemistry Characterization.					
35209056	4	78	theme	Antioxidant	593:603	arg1	activity					656:663	the total antioxidant activity	634:663	the total antioxidant activity	634:663	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	4	78	theme	Antioxidant	593:603	arg1	activity					605:612	Antioxidant activity	593:612	Antioxidant activity	593:612	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	2	79	theme	activity	344:351	arg1	extraction					288:297	extraction	288:297	extraction	288:297	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	79	theme	activity	344:351	arg1	characteristics					363:377	rheology characteristics	354:377	rheology characteristics	354:377	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	79	theme	activity	344:351	arg1	characterization					401:416	physic-chemistry characterization	384:416	physic-chemistry characterization of β-carrageenan	384:433	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	79	theme	activity	344:351	arg1	optimization					300:311	optimization	300:311	optimization	300:311	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	2	79	theme	activity	344:351	arg1	evaluation					318:327	evaluation	318:327	evaluation of antioxidant activity	318:351	This paper focused on the extraction, optimization, and evaluation of antioxidant activity, rheology characteristics, and physic-chemistry characterization of β-carrageenan from Eucheuma gelatinae.					
35209056	12	80	theme	carrageenan	1808:1818	arg1	content					1820:1826	Purity carrageenan content	1801:1826	Purity carrageenan content	1801:1826	Purity carrageenan content got the highest value at 42.68 ± 2.37 (%, DW).					
35209056	10	81	theme	carrageenan	1402:1412	arg1	extraction					1414:1423	antioxidant carrageenan extraction	1390:1423	antioxidant carrageenan extraction	1390:1423	The optimization condition of antioxidant carrageenan extraction was done at 82.35 °C for 115.35 min with a solvent-to-algae ratio of 36.42 (v/w).					
35209056	1	82	theme	seaweed	234:240	arg1	gelatinae					251:259	red seaweed Eucheuma gelatinae	230:259	red seaweed Eucheuma gelatinae	230:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35209056	4	83	theme	power	678:682	arg1	activity					684:691	reducing power activity	669:691	reducing power activity	669:691	Antioxidant activity was evaluated to be the total antioxidant activity and reducing power activity.					
35209056	11	84	theme	antioxidant	1627:1637	arg1	activity					1639:1646	the total antioxidant activity	1617:1646	the total antioxidant activity	1617:1646	At the optimization condition, the extraction efficiency of carrageenan was predicted to be 87.56 ± 5.61 (%), the total antioxidant activity and reducing power activity were predicted to 71.95 ± 5.32 (mg ascorbic acid equivalent/g DW) and 89.84 ± 5.84 (mg FeSO4 equivalent/g DW), respectively.					
35209056	13	85	theme	potential	1929:1937	arg1	use					1939:1941	potential use	1929:1941	potential use in food and pharmaceuticals	1929:1969	Antioxidant carrageenan from Eucheuma gelatinae is of potential use in food and pharmaceuticals.					
35209056	1	86	theme	gelatinae	251:259	arg1	content					219:225	a high content	212:225	a high content of red seaweed Eucheuma gelatinae	212:259	Carrageenan is an anionic sulfated polysaccharide that accounts for a high content of red seaweed Eucheuma gelatinae.					
35344215	0	0	theme	cognitive	69:77	arg1	imbalances					79:88	the metabolic, microbial, and cognitive imbalances	39:88	the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats	39:132	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	2	1	with	combination	361:371	arg1	β-glucan					378:385	β-glucan	378:385	β-glucan (HFS/OB)	378:394	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	1	with	combination	361:371	arg1	starch					407:412	resistant starch	397:412	resistant starch (HFS/OR)	397:421	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	1	with	combination	361:371	arg1	HFS/OR					415:420	HFS/OR	415:420	HFS/OR	415:420	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	1	with	combination	361:371	arg1	HFS/OB					388:393	HFS/OB	388:393	HFS/OB	388:393	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	1	with	combination	361:371	arg1	HFS/OBR					458:464	HFS/OBR	458:464	HFS/OBR	458:464	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	1	with	combination	361:371	arg1	β-glucan					427:434	β-glucan	427:434	β-glucan	427:434	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	9	2	theme	supplementation	1676:1690	arg1	type					1668:1671	the type	1664:1671	the type of supplementation (single or combined fibers)	1664:1718	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	9	3	theme	cognitive	1629:1637	arg1	outcomes					1639:1646	metabolic and cognitive outcomes	1615:1646	metabolic and cognitive outcomes	1615:1646	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	8	4	theme	other	1540:1544	arg1	groups					1546:1551	the other groups	1536:1551	the other groups	1536:1551	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	2	5	theme	resistant	440:448	arg1	starch					450:455	resistant starch	440:455	resistant starch	440:455	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	3	6	theme	body	626:629	arg1	weight					631:636	body weight	626:636	body weight	626:636	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	6	7	theme	Lactobacillus	1163:1175	arg1	abundance					1177:1185	Lactobacillus abundance	1163:1185	Lactobacillus abundance	1163:1185	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	5	8	from	pronounced	977:986	arg1	group					1002:1006	the HFS/OB group	991:1006	the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze	991:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	9	theme	HFS/OB	995:1000	arg1	group					1002:1006	the HFS/OB group	991:1006	the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze	991:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	10	theme	open	1056:1059	arg1	maze					1087:1090	maze	1087:1090	maze	1087:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	10	theme	open	1056:1059	arg1	arms					1061:1064	the open arms	1052:1064	the open arms of the elevated plus maze	1052:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	10	theme	open	1056:1059	arg1	elevated					1073:1080	elevated	1073:1080	elevated	1073:1080	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	4	11	theme	HFS/OB	817:822	arg1	group					824:828	only the HFS/OB group	808:828	only the HFS/OB group	808:828	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	5	12	theme	maze	1087:1090	arg1	maze					1087:1090	maze	1087:1090	maze	1087:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	12	theme	maze	1087:1090	arg1	arms					1061:1064	the open arms	1052:1064	the open arms of the elevated plus maze	1052:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	12	theme	maze	1087:1090	arg1	elevated					1073:1080	elevated	1073:1080	elevated	1073:1080	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	7	13	theme	body	1333:1336	arg1	composition					1338:1348	body composition	1333:1348	body composition in the mice	1333:1360	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	9	14	theme	single	1693:1698	arg1	fibers					1712:1717	single or combined fibers	1693:1717	single or combined fibers	1693:1717	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	9	14	theme	single	1693:1698	arg1	supplementation					1676:1690	supplementation	1676:1690	supplementation (single or combined fibers)	1676:1718	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	9	15	theme	metabolic	1615:1623	arg1	outcomes					1639:1646	metabolic and cognitive outcomes	1615:1646	metabolic and cognitive outcomes	1615:1646	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	9	16	from	influence	1580:1588	arg1	outcomes					1639:1646	metabolic and cognitive outcomes	1615:1646	metabolic and cognitive outcomes	1615:1646	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	1	17	theme	high-fat/sucrose	267:282	arg1	diet					290:293	a high-fat/sucrose (HFS) diet	265:293	a high-fat/sucrose (HFS) diet	265:293	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	0	18	theme	diet-induced	105:116	arg1	obesity					118:124	diet-induced obesity	105:124	diet-induced obesity in rats	105:132	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	7	19	theme	higher	1382:1387	arg1	abundance					1389:1397	a higher abundance	1380:1397	a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS	1380:1459	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	1	20	theme	healthy	160:166	arg1	microbiome					172:181	a healthy gut microbiome	158:181	a healthy gut microbiome	158:181	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	4	21	theme	differential	894:905	arg1	effects					907:913	the differential effects	890:913	the differential effects of fiber types	890:928	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	5	22	theme	most	1033:1036	arg1	time					1038:1041	the most time	1029:1041	the most time spend in the open arms of the elevated plus maze	1029:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	8	23	theme	insulin	1504:1510	arg1	sensitivity					1512:1522	higher insulin sensitivity	1497:1522	higher insulin sensitivity	1497:1522	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	7	24	from	rats	1294:1297	arg1	transplant					1264:1273	Fecal microbiota transplant	1247:1273	Fecal microbiota transplant from fiber-treated rats into germ-free mice	1247:1317	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	1	25	theme	gut	168:170	arg1	microbiome					172:181	a healthy gut microbiome	158:181	a healthy gut microbiome	158:181	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	0	26	theme	fiber	8:12	arg1	combinations					14:25	Dietary fiber combinations	0:25	Dietary fiber combinations	0:25	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	4	27	theme	types	924:928	arg1	effects					907:913	the differential effects	890:913	the differential effects of fiber types	890:928	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	2	28	theme	obese	564:568	arg1	phenotype					570:578	the obese phenotype	560:578	the obese phenotype	560:578	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	3	29	from	decrease	614:621	arg1	weight					631:636	body weight	626:636	body weight	626:636	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	3	29	from	decrease	614:621	arg1	fat					647:649	body fat	642:649	body fat	642:649	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	9	30	theme	dietary	1593:1599	arg1	type					1607:1610	dietary fiber type	1593:1610	dietary fiber type	1593:1610	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	0	31	theme	Dietary	0:6	arg1	combinations					14:25	Dietary fiber combinations	0:25	Dietary fiber combinations	0:25	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	4	32	theme	cognitive	785:793	arg1	function					795:802	cognitive function	785:802	cognitive function	785:802	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	7	33	theme	Fecal	1247:1251	arg1	transplant					1264:1273	Fecal microbiota transplant	1247:1273	Fecal microbiota transplant from fiber-treated rats into germ-free mice	1247:1317	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	1	34	theme	HFS	285:287	arg1	diet					290:293	a high-fat/sucrose (HFS) diet	265:293	a high-fat/sucrose (HFS) diet	265:293	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	9	35	theme	type	1607:1610	arg1	influence					1580:1588	the influence	1576:1588	the influence of dietary fiber type on metabolic and cognitive outcomes	1576:1646	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	7	36	theme	fiber-treated	1280:1292	arg1	rats					1294:1297	fiber-treated rats	1280:1297	fiber-treated rats	1280:1297	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	2	37	theme	High-fiber	296:305	arg1	diets					307:311	High-fiber diets	296:311	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR)	296:465	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	38	theme	resistant	397:405	arg1	HFS/OR					415:420	HFS/OR	415:420	HFS/OR	415:420	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	2	38	theme	resistant	397:405	arg1	starch					407:412	resistant starch	397:412	resistant starch (HFS/OR)	397:421	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	3	39	theme	fiber	660:664	arg1	interventions					666:678	all fiber interventions	656:678	all fiber interventions	656:678	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	4	40	theme	glucose	853:859	arg1	tolerance					861:869	glucose tolerance	853:869	glucose tolerance	853:869	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	3	41	theme	HFS/O	590:594	arg1	group					596:600	Only the HFS/O group	581:600	Only the HFS/O group	581:600	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	2	42	dep	alone	341:345	arg1	HFS/O					348:352	HFS/O	348:352	HFS/O	348:352	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	8	43	theme	recipient	1473:1481	arg1	mice					1483:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	7	44	from	abundance	1389:1397	arg1	groups					1438:1443	the HFS/O and HFS/OB groups	1417:1443	groups	1438:1443	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	8	45	theme	HFS/OB	1466:1471	arg1	mice					1483:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	2	46	theme	obese	492:496	arg1	rats					498:501	diet-induced obese rats	479:501	diet-induced obese rats	479:501	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	9	47	theme	fiber	1601:1605	arg1	type					1607:1610	dietary fiber type	1593:1610	dietary fiber type	1593:1610	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	6	48	theme	fiber	1097:1101	arg1	groups					1103:1108	All fiber groups	1093:1108	All fiber groups	1093:1108	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	7	49	theme	microbiota	1253:1262	arg1	transplant					1264:1273	Fecal microbiota transplant	1247:1273	Fecal microbiota transplant from fiber-treated rats into germ-free mice	1247:1317	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	3	50	theme	cognitive	713:721	arg1	function					723:730	cognitive function	713:730	cognitive function	713:730	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	2	51	theme	diet-induced	479:490	arg1	rats					498:501	diet-induced obese rats	479:501	diet-induced obese rats	479:501	High-fiber diets consisting of oligofructose alone (HFS/O) or in combination with β-glucan (HFS/OB), resistant starch (HFS/OR), or β-glucan and resistant starch (HFS/OBR) were fed to diet-induced obese rats for 8 weeks to determine if these fibers could attenuate the obese phenotype.					
35344215	6	52	theme	beneficial	1132:1141	arg1	Bifidobacterium					1143:1157	beneficial Bifidobacterium	1132:1157	beneficial Bifidobacterium	1132:1157	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	8	53	contain	had	1493:1495	arg2	sensitivity					1512:1522	higher insulin sensitivity	1497:1522	higher insulin sensitivity	1497:1522	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	8	53	contain	had	1493:1495	arg1	mice					1483:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice	1462:1486	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	5	54	from	group	1002:1006	arg1	pronounced					977:986	pronounced	977:986	pronounced	977:986	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	7	55	theme	HFS/O	1421:1425	arg1	groups					1438:1443	the HFS/O and HFS/OB groups	1417:1443	groups	1438:1443	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	5	56	dep	time	1038:1041	arg1	spend					1043:1047	spend	1043:1047	spend in the open arms of the elevated plus maze	1043:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	6	57	theme	Clostridium	1234:1244	arg1	abundance					1221:1229	higher abundance	1214:1229	higher abundance of Clostridium	1214:1244	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	3	58	theme	insulin	689:695	arg1	sensitivity					697:707	insulin sensitivity	689:707	insulin sensitivity	689:707	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	7	59	theme	germ-free	1304:1312	arg1	mice					1314:1317	germ-free mice	1304:1317	germ-free mice	1304:1317	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	9	60	theme	specific	1741:1748	arg1	outcomes					1759:1766	specific targeted outcomes	1741:1766	specific targeted outcomes	1741:1766	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	0	61	theme	metabolic	43:51	arg1	imbalances					79:88	the metabolic, microbial, and cognitive imbalances	39:88	the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats	39:132	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	8	62	theme	higher	1497:1502	arg1	sensitivity					1512:1522	higher insulin sensitivity	1497:1522	higher insulin sensitivity	1497:1522	The HFS/OB recipient mice also had higher insulin sensitivity compared to the other groups.					
35344215	7	63	theme	HFS/OB	1431:1436	arg1	groups					1438:1443	the HFS/O and HFS/OB groups	1417:1443	groups	1438:1443	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	6	64	theme	HFS	1197:1199	arg1	group					1201:1205	the HFS group	1193:1205	the HFS group	1193:1205	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	5	65	theme	elevated	1073:1080	arg1	maze					1087:1090	maze	1087:1090	maze	1087:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	65	theme	elevated	1073:1080	arg1	arms					1061:1064	the open arms	1052:1064	the open arms of the elevated plus maze	1052:1090	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	65	theme	elevated	1073:1080	arg1	elevated					1073:1080	elevated	1073:1080	elevated	1073:1080	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	4	66	from	improvements	837:848	arg1	tolerance					861:869	glucose tolerance	853:869	glucose tolerance	853:869	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	5	67	theme	Hippocampal	931:941	arg1	cytokines					943:951	Hippocampal cytokines	931:951	Hippocampal cytokines (IL-6, IL-10)	931:965	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	9	68	theme	targeted	1750:1757	arg1	outcomes					1759:1766	specific targeted outcomes	1741:1766	specific targeted outcomes	1741:1766	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	6	69	from	increase	1120:1127	arg1	abundance					1177:1185	Lactobacillus abundance	1163:1185	Lactobacillus abundance	1163:1185	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	6	69	from	increase	1120:1127	arg1	Bifidobacterium					1143:1157	beneficial Bifidobacterium	1132:1157	beneficial Bifidobacterium	1132:1157	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	6	70	theme	higher	1214:1219	arg1	abundance					1221:1229	higher abundance	1214:1229	higher abundance of Clostridium	1214:1244	All fiber groups showed an increase in beneficial Bifidobacterium and Lactobacillus abundance while the HFS group showed higher abundance of Clostridium.					
35344215	9	71	theme	combined	1703:1710	arg1	fibers					1712:1717	single or combined fibers	1693:1717	single or combined fibers	1693:1717	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	9	71	theme	combined	1703:1710	arg1	supplementation					1676:1690	supplementation	1676:1690	supplementation (single or combined fibers)	1676:1718	This study highlights the influence of dietary fiber type on metabolic and cognitive outcomes suggesting that the type of supplementation (single or combined fibers) could be tailored to specific targeted outcomes.					
35344215	7	72	from	composition	1338:1348	arg1	mice					1357:1360	the mice	1353:1360	the mice	1353:1360	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	1	73	theme	unfavorable	220:230	arg1	changes					242:248	the unfavorable microbial changes	216:248	the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet	216:293	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	4	74	theme	fiber	918:922	arg1	types					924:928	fiber types	918:928	fiber types	918:928	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	5	75	dep	cytokines	943:951	arg1	IL-10					960:964	IL-10	960:964	IL-10	960:964	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	5	75	dep	cytokines	943:951	arg1	IL-6					954:957	IL-6	954:957	IL-6	954:957	Hippocampal cytokines (IL-6, IL-10) were more pronounced in the HFS/OB group which coincided with the most time spend in the open arms of the elevated plus maze.					
35344215	1	76	theme	Dietary	135:141	arg1	fiber					143:147	Dietary fiber	135:147	Dietary fiber	135:147	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	1	77	theme	microbial	232:240	arg1	changes					242:248	the unfavorable microbial changes	216:248	the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet	216:293	Dietary fiber promotes a healthy gut microbiome and shows promise in attenuating the unfavorable microbial changes resulting from a high-fat/sucrose (HFS) diet.					
35344215	0	78	theme	microbial	54:62	arg1	imbalances					79:88	the metabolic, microbial, and cognitive imbalances	39:88	the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats	39:132	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
35344215	7	79	theme	Bacteroides	1402:1412	arg1	abundance					1389:1397	a higher abundance	1380:1397	a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS	1380:1459	Fecal microbiota transplant from fiber-treated rats into germ-free mice did not alter body composition in the mice but did result in a higher abundance of Bacteroides in the HFS/O and HFS/OB groups compared to HFS.					
35344215	4	80	theme	HFS/O	737:741	arg1	diet					743:746	The HFS/O diet	733:746	The HFS/O diet	733:746	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	4	80	theme	HFS/O	737:741	arg1	effective					762:770	effective	762:770	effective	762:770	The HFS/O diet was the least effective at improving cognitive function and only the HFS/OB group showed improvements in glucose tolerance, thus highlighting the differential effects of fiber types.					
35344215	3	81	theme	body	642:645	arg1	fat					647:649	body fat	642:649	body fat	642:649	Only the HFS/O group displayed a decrease in body weight and body fat, but all fiber interventions improved insulin sensitivity and cognitive function.					
35344215	0	82	from	obesity	118:124	arg1	rats					129:132	rats	129:132	rats	129:132	Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats.					
36831116	4	0	dep	monogalactosylated	866:883	arg1	NeuAc1					900:905	Hex4HexNAc4 ± NeuAc1	886:905	Hex4HexNAc4 ± NeuAc1	886:905	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	0	1	with	Patient	33:39	arg1	Variant					65:71	a Novel Hemizygous Variant	46:71	a Novel Hemizygous Variant	46:71	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.					
36831116	1	2	theme	rare	133:136	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	7	3	theme	other	1379:1383	arg1	defects					1385:1391	other defects	1379:1391	other defects	1379:1391	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	1	4	theme	inherited	138:146	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	2	5	theme	Golgi	486:490	arg1	apparatus					492:500	Golgi apparatus	486:500	Golgi apparatus	486:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	3	6	theme	serum	642:646	arg1	N-glycans					648:656	serum N-glycans	642:656	serum N-glycans	642:656	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	5	7	theme	hemizygous	1008:1017	arg1	p.Leu154Pro					1031:1041	p.Leu154Pro	1031:1041	p.Leu154Pro	1031:1041	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	5	7	theme	hemizygous	1008:1017	arg1	C					1028:1028	hemizygous c.461T > C	1008:1028	de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene	1000:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	3	8	theme	serum	527:531	arg1	transferrin					533:543	serum transferrin	527:543	serum transferrin	527:543	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	5	9	theme	SLC35A2	1060:1066	arg1	gene					1068:1071	the SLC35A2 gene	1056:1071	the SLC35A2 gene	1056:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	5	10	theme	whole	946:950	arg1	sequencing					958:967	whole exome sequencing	946:967	whole exome sequencing	946:967	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	2	11	theme	novel	316:320	arg1	variant					331:337	a novel missense variant	314:337	a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	314:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	2	12	theme	reticulum	472:480	arg1	lumen					447:451	the lumen	443:451	the lumen of the endoplasmic reticulum and Golgi apparatus	443:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	5	13	theme	exome	952:956	arg1	sequencing					958:967	whole exome sequencing	946:967	whole exome sequencing	946:967	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	1	14	theme	metabolic	148:156	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	2	15	theme	endoplasmic	460:470	arg1	reticulum					472:480	the endoplasmic reticulum	456:480	the endoplasmic reticulum	456:480	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	4	16	theme	serum	750:754	arg1	N-glycoprofile					756:769	An abnormal serum N-glycoprofile	738:769	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	738:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	1	17	theme	Congenital	74:83	arg1	group					124:128	a group	122:128	a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	122:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	17	theme	Congenital	74:83	arg1	disorders					85:93	Congenital disorders	74:93	Congenital disorders of glycosylation (CDG)	74:116	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	17	theme	Congenital	74:83	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	18	theme	disorders	158:166	arg1	disorders					85:93	Congenital disorders	74:93	Congenital disorders of glycosylation (CDG)	74:116	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	18	theme	disorders	158:166	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	18	theme	disorders	158:166	arg1	group					124:128	a group	122:128	a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	122:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	3	19	theme	transferrin	533:543	arg1	Isoelectric					503:513	Isoelectric	503:513	Isoelectric	503:513	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	7	20	from	CDGs	1371:1374	arg1	metabolism					1410:1419	the galactose metabolism	1396:1419	the galactose metabolism	1396:1419	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	5	21	dep	de	1000:1001	arg1	novo					1003:1006	novo	1003:1006	novo	1003:1006	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	4	22	dep	agalactosylated	810:824	arg1	Hex3HexNAc5Fuc1					845:859	Hex3HexNAc5Fuc1	845:859	Hex3HexNAc5Fuc1	845:859	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	4	22	dep	agalactosylated	810:824	arg1	Hex3HexNAc4-5					827:839	Hex3HexNAc4-5	827:839	Hex3HexNAc4-5	827:839	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	3	23	theme	apolipoprotein	686:699	arg1	CIII					701:704	apolipoprotein CIII	686:704	apolipoprotein CIII O-glycans	686:714	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	4	24	theme	agalactosylated	810:824	arg1	N-glycans					908:916	agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	810:916	agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	810:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	2	25	from	variant	331:337	arg1	gene					354:357	the SLC35A2 gene	342:357	the SLC35A2 gene	342:357	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	6	26	theme	analytical	1115:1124	arg1	approaches					1139:1148	biochemical, analytical, and genomic approaches	1102:1148	biochemical, analytical, and genomic approaches	1102:1148	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	4	27	with	N-glycoprofile	756:769	arg1	levels					800:805	significantly increased levels	776:805	significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	776:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	7	28	theme	other	1365:1369	arg1	CDGs					1371:1374	other CDGs	1365:1374	other CDGs	1365:1374	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	3	29	theme	CIII	701:704	arg1	O-glycans					706:714	apolipoprotein CIII O-glycans	686:714	apolipoprotein CIII O-glycans	686:714	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	5	30	theme	c.461T	1019:1024	arg1	p.Leu154Pro					1031:1041	p.Leu154Pro	1031:1041	p.Leu154Pro	1031:1041	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	5	30	theme	c.461T	1019:1024	arg1	C					1028:1028	hemizygous c.461T > C	1008:1028	de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene	1000:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	1	31	theme	glycosylation	98:110	arg1	group					124:128	a group	122:128	a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	122:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	31	theme	glycosylation	98:110	arg1	disorders					85:93	Congenital disorders	74:93	Congenital disorders of glycosylation (CDG)	74:116	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	1	31	theme	glycosylation	98:110	arg1	disorders					158:166	rare inherited metabolic disorders	133:166	rare inherited metabolic disorders caused by a defect in the process of protein glycosylation	133:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	5	32	theme	de	1000:1001	arg1	mutation					1044:1051	de novo hemizygous c.461T > C (p.Leu154Pro) mutation	1000:1051	de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene	1000:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	2	33	theme	galactose	369:377	arg1	transporter					379:389	a galactose transporter	367:389	a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	367:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	0	34	theme	SLC35A2-CDG	20:30	arg1	N-Glycoprofiling					0:15	N-Glycoprofiling	0:15	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.	0:72	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.					
36831116	4	35	theme	±	898:898	arg1	NeuAc1					900:905	Hex4HexNAc4 ± NeuAc1	886:905	Hex4HexNAc4 ± NeuAc1	886:905	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	2	36	theme	comprehensive	255:267	arg1	analysis					282:289	a comprehensive glycoprofile analysis	253:289	a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	253:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	7	37	theme	aberrant	1248:1255	arg1	N-glycans					1257:1265	identified aberrant N-glycans	1237:1265	identified aberrant N-glycans	1237:1265	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	4	38	theme	N-glycans	908:916	arg1	levels					800:805	significantly increased levels	776:805	significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	776:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	7	39	theme	N-glycans	1257:1265	arg1	N-glycans					1257:1265	identified aberrant N-glycans	1237:1265	identified aberrant N-glycans	1237:1265	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	7	39	theme	N-glycans	1257:1265	arg1	specific					1274:1281	specific	1274:1281	specific	1274:1281	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	7	39	theme	N-glycans	1257:1265	arg1	set					1230:1232	the set	1226:1232	the set of identified aberrant N-glycans	1226:1265	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	4	40	theme	abnormal	741:748	arg1	N-glycoprofile					756:769	An abnormal serum N-glycoprofile	738:769	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	738:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	7	41	theme	other	1287:1291	arg1	variants					1293:1300	other variants	1287:1300	other variants causing SLC35A2-CDG	1287:1320	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	7	42	theme	galactose	1400:1408	arg1	metabolism					1410:1419	the galactose metabolism	1396:1419	the galactose metabolism	1396:1419	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	2	43	attach	present	245:251	arg2	we					242:243	we	242:243	we	242:243	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	2	43	attach	present	245:251	arg1	work					236:239	this work	231:239	this work	231:239	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	2	44	theme	apparatus	492:500	arg1	lumen					447:451	the lumen	443:451	the lumen of the endoplasmic reticulum and Golgi apparatus	443:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	6	45	theme	approaches	1139:1148	arg1	combination					1087:1097	the combination	1083:1097	the combination of biochemical, analytical, and genomic approaches	1083:1148	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	5	46	from	mutation	1044:1051	arg1	gene					1068:1071	the SLC35A2 gene	1056:1071	the SLC35A2 gene	1056:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	0	47	theme	Novel	48:52	arg1	Variant					65:71	a Novel Hemizygous Variant	46:71	a Novel Hemizygous Variant	46:71	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.					
36831116	3	48	theme	mass	719:722	arg1	spectrometry					724:735	mass spectrometry	719:735	mass spectrometry	719:735	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	4	49	theme	monogalactosylated	866:883	arg1	N-glycans					908:916	agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	810:916	agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	810:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	2	50	with	patient	301:307	arg1	variant					331:337	a novel missense variant	314:337	a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	314:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	4	51	theme	increased	790:798	arg1	levels					800:805	significantly increased levels	776:805	significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans	776:916	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	7	52	theme	identified	1237:1246	arg1	N-glycans					1257:1265	identified aberrant N-glycans	1237:1265	identified aberrant N-glycans	1237:1265	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	3	53	theme	O-glycans	706:714	arg1	analysis					614:621	structural analysis	603:621	structural analysis of transferrin and serum N-glycans	603:656	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	3	53	theme	O-glycans	706:714	arg1	analysis					674:681	the analysis	670:681	the analysis of apolipoprotein CIII O-glycans	670:714	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	5	54	theme	>	1026:1026	arg1	p.Leu154Pro					1031:1041	p.Leu154Pro	1031:1041	p.Leu154Pro	1031:1041	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	5	54	theme	>	1026:1026	arg1	C					1028:1028	hemizygous c.461T > C	1008:1028	de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene	1000:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	5	55	theme	C	1028:1028	arg1	mutation					1044:1051	de novo hemizygous c.461T > C (p.Leu154Pro) mutation	1000:1051	de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene	1000:1071	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	2	56	theme	patient	301:307	arg1	analysis					282:289	a comprehensive glycoprofile analysis	253:289	a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	253:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	6	57	theme	N-glycan	1174:1181	arg1	biomarkers					1183:1192	distinctive N-glycan biomarkers	1162:1192	distinctive N-glycan biomarkers	1162:1192	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	3	58	theme	type	570:573	arg1	pattern					578:584	a CDG type II pattern	564:584	a CDG type II pattern	564:584	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	4	59	theme	Hex4HexNAc4	886:896	arg1	NeuAc1					900:905	Hex4HexNAc4 ± NeuAc1	886:905	Hex4HexNAc4 ± NeuAc1	886:905	An abnormal serum N-glycoprofile with significantly increased levels of agalactosylated (Hex3HexNAc4-5 and Hex3HexNAc5Fuc1) and monogalactosylated (Hex4HexNAc4 ± NeuAc1) N-glycans was observed.					
36831116	3	60	theme	transferrin	626:636	arg1	analysis					614:621	structural analysis	603:621	structural analysis of transferrin and serum N-glycans	603:656	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	3	60	theme	transferrin	626:636	arg1	analysis					674:681	the analysis	670:681	the analysis of apolipoprotein CIII O-glycans	670:714	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	6	61	theme	distinctive	1162:1172	arg1	biomarkers					1183:1192	distinctive N-glycan biomarkers	1162:1192	distinctive N-glycan biomarkers	1162:1192	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	1	62	from	defect	180:185	arg1	process					194:200	the process	190:200	the process of protein glycosylation	190:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	2	63	theme	male	296:299	arg1	patient					301:307	a male patient	294:307	a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	294:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	2	64	theme	glycoprofile	269:280	arg1	analysis					282:289	a comprehensive glycoprofile analysis	253:289	a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	253:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	6	65	theme	biochemical	1102:1112	arg1	approaches					1139:1148	biochemical, analytical, and genomic approaches	1102:1148	biochemical, analytical, and genomic approaches	1102:1148	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	3	66	theme	structural	603:612	arg1	analysis					614:621	structural analysis	603:621	structural analysis of transferrin and serum N-glycans	603:656	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	5	67	theme	Sanger	973:978	arg1	sequencing					980:989	Sanger sequencing	973:989	Sanger sequencing	973:989	Additionally, whole exome sequencing and Sanger sequencing revealed de novo hemizygous c.461T > C (p.Leu154Pro) mutation in the SLC35A2 gene.					
36831116	6	68	theme	genomic	1131:1137	arg1	approaches					1139:1148	biochemical, analytical, and genomic approaches	1102:1148	biochemical, analytical, and genomic approaches	1102:1148	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	7	69	dep	CDGs	1371:1374	arg1	the					1361:1363	the	1361:1363	the	1361:1363	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	3	70	theme	CDG	566:568	arg1	pattern					578:584	a CDG type II pattern	564:584	a CDG type II pattern	564:584	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	6	71	theme	biomarkers	1183:1192	arg1	biomarkers					1183:1192	distinctive N-glycan biomarkers	1162:1192	distinctive N-glycan biomarkers	1162:1192	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	6	71	theme	biomarkers	1183:1192	arg1	set					1155:1157	the set	1151:1157	the set of distinctive N-glycan biomarkers	1151:1192	Based on the combination of biochemical, analytical, and genomic approaches, the set of distinctive N-glycan biomarkers was characterized.					
36831116	2	72	theme	SLC35A2	346:352	arg1	gene					354:357	the SLC35A2 gene	342:357	the SLC35A2 gene	342:357	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	1	73	theme	protein	205:211	arg1	glycosylation					213:225	protein glycosylation	205:225	protein glycosylation	205:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
36831116	0	74	theme	Hemizygous	54:63	arg1	Variant					65:71	a Novel Hemizygous Variant	46:71	a Novel Hemizygous Variant	46:71	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.					
36831116	3	75	theme	N-glycans	648:656	arg1	analysis					614:621	structural analysis	603:621	structural analysis of transferrin and serum N-glycans	603:656	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	3	75	theme	N-glycans	648:656	arg1	analysis					674:681	the analysis	670:681	the analysis of apolipoprotein CIII O-glycans	670:714	Isoelectric focusing of serum transferrin, which resulted in a CDG type II pattern, was followed by structural analysis of transferrin and serum N-glycans, as well as the analysis of apolipoprotein CIII O-glycans by mass spectrometry.					
36831116	0	76	dep	N-Glycoprofiling	0:15	arg1	Patient					33:39	Patient	33:39	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.	0:72	N-Glycoprofiling of SLC35A2-CDG: Patient with a Novel Hemizygous Variant.					
36831116	2	77	theme	missense	322:329	arg1	variant					331:337	a novel missense variant	314:337	a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus	314:500	In this work, we present a comprehensive glycoprofile analysis of a male patient with a novel missense variant in the SLC35A2 gene, coding a galactose transporter that translocates UDP-galactose from the cytosol to the lumen of the endoplasmic reticulum and Golgi apparatus.					
36831116	7	78	from	defects	1385:1391	arg1	metabolism					1410:1419	the galactose metabolism	1396:1419	the galactose metabolism	1396:1419	Potentially, the set of identified aberrant N-glycans can be specific for other variants causing SLC35A2-CDG and can distinguish this disorder from the other CDGs or other defects in the galactose metabolism.					
36831116	1	79	theme	glycosylation	213:225	arg1	process					194:200	the process	190:200	the process of protein glycosylation	190:225	Congenital disorders of glycosylation (CDG) are a group of rare inherited metabolic disorders caused by a defect in the process of protein glycosylation.					
37343749	8	0	theme	AP	1215:1216	arg1	fibers					1218:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	9	1	theme	fiber	1437:1441	arg1	matrices					1443:1450	fiber matrices	1437:1450	fiber matrices	1437:1450	Their low density and high cellulosic content will improve their ability to fiber matrices.					
37343749	5	2	theme	improved	841:848	arg1	roughness					858:866	the improved surface roughness	837:866	the improved surface roughness	837:866	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	6	3	theme	XRD	935:937	arg1	analysis					939:946	XRD analysis	935:946	XRD analysis	935:946	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	2	4	theme	eco-friendly	348:359	arg1	goods					361:365	eco-friendly goods	348:365	eco-friendly goods	348:365	Natural plants like hemp, cotton, and bamboo are great options for knitters and crocheters looking to make eco-friendly goods.					
37343749	8	5	theme	pectin	1290:1295	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	5	theme	pectin	1290:1295	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	4	6	theme	structural	745:754	arg1	changes					756:762	structural changes	745:762	structural changes	745:762	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	8	7	theme	lignin	1273:1278	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	7	theme	lignin	1273:1278	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	2	8	theme	great	290:294	arg1	plants					249:254	Natural plants	241:254	Natural plants like hemp, cotton, and bamboo	241:284	Natural plants like hemp, cotton, and bamboo are great options for knitters and crocheters looking to make eco-friendly goods.					
37343749	2	8	theme	great	290:294	arg1	options					296:302	great options	290:302	great options for knitters and crocheters looking to make eco-friendly goods	290:365	Natural plants like hemp, cotton, and bamboo are great options for knitters and crocheters looking to make eco-friendly goods.					
37343749	4	9	theme	tensile	700:706	arg1	capabilities					708:719	tensile capabilities	700:719	tensile capabilities	700:719	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	10	10	theme	AP	1477:1478	arg1	fiber					1480:1484	AP fiber	1477:1484	AP fiber	1477:1484	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	6	11	theme	untreated	1063:1071	arg1	APF					1073:1075	untreated APF	1063:1075	untreated APF	1063:1075	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	12	theme	lower	1232:1236	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	10	13	theme	TG-DTA	1530:1535	arg1	analysis					1537:1544	TG-DTA analysis	1530:1544	TG-DTA analysis	1530:1544	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	5	14	theme	fiber	875:879	arg1	roughness					858:866	the improved surface roughness	837:866	the improved surface roughness	837:866	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	4	15	theme	AP	655:656	arg1	fibers					658:663	AP fibers	655:663	the AP fibers' morphology	651:675	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	3	16	theme	pennata	464:470	arg1	plant					477:481	the Acacia pennata (AP) plant	453:481	the Acacia pennata (AP) plant	453:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	5	17	theme	pXRD	815:818	arg1	analyses					820:827	The SEM image and pXRD analyses	797:827	analyses	820:827	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	1	18	theme	natural	178:184	arg1	fibers					203:208	natural cellulosic woody fibers	178:208	natural cellulosic woody fibers	178:208	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	5	19	theme	surface	850:856	arg1	roughness					858:866	the improved surface roughness	837:866	the improved surface roughness	837:866	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	0	20	theme	alkali-treated	46:59	arg1	fiber					76:80	alkali-treated Acacia pennata fiber	46:80	alkali-treated Acacia pennata fiber	46:80	Physico-chemical and extraction properties on alkali-treated Acacia pennata fiber.					
37343749	3	21	theme	basic	499:503	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	1	22	theme	cellulosic	186:195	arg1	fibers					203:208	natural cellulosic woody fibers	178:208	natural cellulosic woody fibers	178:208	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	7	23	theme	Alkali-treated	1078:1091	arg1	fibers					1096:1101	Alkali-treated AP fibers	1078:1101	Alkali-treated AP fibers	1078:1101	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	8	24	theme	moisture	1323:1330	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	24	theme	moisture	1323:1330	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	10	25	theme	tensile	1551:1557	arg1	strength					1559:1566	tensile strength	1551:1566	tensile strength	1551:1566	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	3	26	theme	thermal	535:541	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	1	27	theme	woody	197:201	arg1	fibers					203:208	natural cellulosic woody fibers	178:208	natural cellulosic woody fibers	178:208	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	7	28	theme	AP	1093:1094	arg1	fibers					1096:1101	Alkali-treated AP fibers	1078:1101	Alkali-treated AP fibers	1078:1101	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	1	29	theme	reinforced	101:110	arg1	materials					122:130	reinforced composite materials	101:130	reinforced composite materials	101:130	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	4	30	theme	morphological	722:734	arg1	changes					736:742	morphological changes	722:742	morphological changes	722:742	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	1	31	theme	fibers	203:208	arg1	use					171:173	the use	167:173	the use of natural cellulosic woody fibers as good sustainable resources	167:238	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	3	32	theme	current	372:378	arg1	study					380:384	The current study	368:384	The current study	368:384	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	10	33	theme	thermal	1457:1463	arg1	behavior					1465:1472	The thermal behavior	1453:1472	The thermal behavior of AP fiber at various temperatures	1453:1508	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	9	34	theme	high	1383:1386	arg1	content					1399:1405	high cellulosic content	1383:1405	high cellulosic content	1383:1405	Their low density and high cellulosic content will improve their ability to fiber matrices.					
37343749	1	35	theme	composite	112:120	arg1	materials					122:130	reinforced composite materials	101:130	reinforced composite materials	101:130	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	3	36	theme	Acacia	457:462	arg1	plant					477:481	the Acacia pennata (AP) plant	453:481	the Acacia pennata (AP) plant	453:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	7	37	theme	5.13	1192:1195	arg1	%					1196:1196	5.13%	1192:1196	5.13%	1192:1196	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	7	37	theme	5.13	1192:1195	arg1	ash					1187:1189	ash	1187:1189	ash (5.13%)	1187:1197	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	8	38	contain	have	1225:1228	arg2	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg1	fibers					1218:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	38	contain	have	1225:1228	arg2	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	1	39	theme	materials	122:130	arg1	production					87:96	The production	83:96	The production of reinforced composite materials	83:130	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	10	40	theme	various	1489:1495	arg1	temperatures					1497:1508	various temperatures	1489:1508	various temperatures	1489:1508	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	1	41	theme	good	213:216	arg1	resources					230:238	good sustainable resources	213:238	good sustainable resources	213:238	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	3	42	theme	natural	413:419	arg1	fiber					421:425	natural fiber	413:425	natural fiber obtained from the stem of the Acacia pennata (AP) plant	413:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	6	43	theme	SEM	1031:1033	arg1	pictograms					1035:1044	their SEM pictograms	1025:1044	their SEM pictograms in comparison to untreated APF	1025:1075	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	9	44	theme	low	1367:1369	arg1	density					1371:1377	Their low density	1361:1377	Their low density	1361:1377	Their low density and high cellulosic content will improve their ability to fiber matrices.					
37343749	4	45	theme	alkali	625:630	arg1	treatment					632:640	alkali treatment	625:640	alkali treatment	625:640	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	1	46	theme	sustainable	218:228	arg1	resources					230:238	good sustainable resources	213:238	good sustainable resources	213:238	The production of reinforced composite materials can generally benefit greatly from the use of natural cellulosic woody fibers as good sustainable resources.					
37343749	3	47	theme	fiber	421:425	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	3	47	theme	fiber	421:425	arg1	properties					399:408	the properties	395:408	the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant	395:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	4	48	theme	thermal	769:775	arg1	degradation					777:787	thermal degradation	769:787	thermal degradation (APFs)	769:794	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	4	48	theme	thermal	769:775	arg1	APFs					790:793	APFs	790:793	APFs	790:793	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	5	49	theme	SEM	801:803	arg1	image					805:809	The SEM image and pXRD analyses	797:827	image	805:809	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	0	50	theme	pennata	68:74	arg1	fiber					76:80	alkali-treated Acacia pennata fiber	46:80	alkali-treated Acacia pennata fiber	46:80	Physico-chemical and extraction properties on alkali-treated Acacia pennata fiber.					
37343749	8	51	theme	untreated	1346:1354	arg1	APF					1356:1358	untreated APF	1346:1358	untreated APF	1346:1358	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	52	theme	hemi-cellulose	1248:1261	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	2	53	theme	Natural	241:247	arg1	plants					249:254	Natural plants	241:254	Natural plants like hemp, cotton, and bamboo	241:284	Natural plants like hemp, cotton, and bamboo are great options for knitters and crocheters looking to make eco-friendly goods.					
37343749	2	53	theme	Natural	241:247	arg1	options					296:302	great options	290:302	great options for knitters and crocheters looking to make eco-friendly goods	290:365	Natural plants like hemp, cotton, and bamboo are great options for knitters and crocheters looking to make eco-friendly goods.					
37343749	10	54	theme	fiber	1480:1484	arg1	behavior					1465:1472	The thermal behavior	1453:1472	The thermal behavior of AP fiber at various temperatures	1453:1508	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	0	55	theme	Acacia	61:66	arg1	fiber					76:80	alkali-treated Acacia pennata fiber	46:80	alkali-treated Acacia pennata fiber	46:80	Physico-chemical and extraction properties on alkali-treated Acacia pennata fiber.					
37343749	3	56	theme	mechanical	548:557	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	6	57	from	pictograms	1035:1044	arg1	comparison					1049:1058	comparison	1049:1058	comparison to untreated APF	1049:1075	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	3	58	theme	plant	477:481	arg1	stem					445:448	the stem	441:448	the stem of the Acacia pennata (AP) plant	441:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	10	59	from	temperatures	1497:1508	arg1	behavior					1465:1472	The thermal behavior	1453:1472	The thermal behavior of AP fiber at various temperatures	1453:1508	The thermal behavior of AP fiber at various temperatures was demonstrated by TG-DTA analysis, and tensile strength was also investigated.					
37343749	9	60	theme	cellulosic	1388:1397	arg1	content					1399:1405	high cellulosic content	1383:1405	high cellulosic content	1383:1405	Their low density and high cellulosic content will improve their ability to fiber matrices.					
37343749	4	61	theme	chemical	678:685	arg1	composition					687:697	chemical composition	678:697	chemical composition	678:697	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	3	62	theme	structural	523:532	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	4	63	theme	key	580:582	arg1	goal					584:587	The key goal	576:587	The key goal of this work	576:600	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	5	64	theme	alkaline	910:917	arg1	treatment					919:927	the alkaline treatment	906:927	the alkaline treatment	906:927	The SEM image and pXRD analyses support the improved surface roughness of the fiber, and that was seen after the alkaline treatment.					
37343749	8	65	theme	wax	1306:1308	arg1	lignin					1273:1278	lignin	1273:1278	lignin (20.96%)	1273:1287	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	moisture					1323:1330	moisture	1323:1330	moisture (13.44%)	1323:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	pectin					1290:1295	pectin	1290:1295	pectin (8.77%)	1290:1303	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	hemi-cellulose					1248:1261	hemi-cellulose	1248:1261	hemi-cellulose (30.30%)	1248:1270	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	%					1315:1315	0.12%	1311:1315	0.12%	1311:1315	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	%					1286:1286	20.96%	1281:1286	20.96%	1281:1286	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	%					1338:1338	13.44%	1333:1338	13.44%	1333:1338	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	%					1302:1302	8.77%	1298:1302	8.77%	1298:1302	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	%					1269:1269	30.30%	1264:1269	30.30%	1264:1269	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	amount					1238:1243	a lower amount	1230:1243	a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%)	1230:1339	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	8	65	theme	wax	1306:1308	arg1	wax					1306:1308	wax	1306:1308	wax (0.12%)	1306:1316	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	3	66	theme	physico-chemical	505:520	arg1	characteristics					559:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	its basic physico-chemical, structural, thermal, and mechanical characteristics	495:573	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	3	67	theme	AP	473:474	arg1	plant					477:481	the Acacia pennata (AP) plant	453:481	the Acacia pennata (AP) plant	453:481	The current study examines the properties of natural fiber obtained from the stem of the Acacia pennata (AP) plant, as well as its basic physico-chemical, structural, thermal, and mechanical characteristics.					
37343749	7	68	theme	chemical	1134:1141	arg1	ash					1187:1189	ash	1187:1189	ash (5.13%)	1187:1197	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	7	68	theme	chemical	1134:1141	arg1	cellulose					1164:1172	cellulose	1164:1172	cellulose (51.38%)	1164:1181	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	7	68	theme	chemical	1134:1141	arg1	components					1143:1152	chemical components	1134:1152	chemical components including cellulose (51.38%) and ash (5.13%)	1134:1197	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	6	69	theme	crystallinity	959:971	arg1	index					973:977	the fiber crystallinity index	949:977	the fiber crystallinity index (54.65%)	949:986	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	6	69	theme	crystallinity	959:971	arg1	%					985:985	54.65%	980:985	54.65%	980:985	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	4	70	theme	work	597:600	arg1	goal					584:587	The key goal	576:587	The key goal of this work	576:600	The key goal of this work was to investigate how alkali treatment affected the AP fibers' morphology, chemical composition, tensile capabilities, morphological changes, structural changes, and thermal degradation (APFs).					
37343749	8	71	theme	Alkali-treated	1200:1213	arg1	fibers					1218:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers	1200:1223	Alkali-treated AP fibers have a lower amount of hemi-cellulose (30.30%), lignin (20.96%), pectin (8.77%), wax (0.12%), and moisture (13.44%) than untreated APF.					
37343749	7	72	theme	components	1143:1152	arg1	percentage					1120:1129	a higher percentage	1111:1129	a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%)	1111:1197	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
37343749	0	73	from	properties	32:41	arg1	fiber					76:80	alkali-treated Acacia pennata fiber	46:80	alkali-treated Acacia pennata fiber	46:80	Physico-chemical and extraction properties on alkali-treated Acacia pennata fiber.					
37343749	6	74	theme	fiber	953:957	arg1	index					973:977	the fiber crystallinity index	949:977	the fiber crystallinity index (54.65%)	949:986	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	6	74	theme	fiber	953:957	arg1	%					985:985	54.65%	980:985	54.65%	980:985	From XRD analysis, the fiber crystallinity index (54.65%) was improved and it was connected to their SEM pictograms in comparison to untreated APF.					
37343749	7	75	theme	higher	1113:1118	arg1	percentage					1120:1129	a higher percentage	1111:1129	a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%)	1111:1197	Alkali-treated AP fibers include a higher percentage of chemical components including cellulose (51.38%) and ash (5.13%).					
36436847	1	0	theme	structural	292:301	arg1	orders					303:308	starch structural orders	285:308	starch structural orders	285:308	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	2	1	theme	different	507:515	arg1	forms					526:530	different physical forms	507:530	different physical forms	507:530	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	5	2	theme	barley	1014:1019	arg1	structure					1028:1036	the blue highland barley kernel structure	996:1036	the blue highland barley kernel structure	996:1036	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	1	3	theme	starch	203:208	arg1	properties					220:229	the low starch digestive properties	195:229	the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure	195:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	0	4	theme	structure	61:69	arg1	Effects					0:6	Effects	0:6	Effects of composition, starch structural orders, and kernel structure on starch	0:79	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	1	5	theme	orders	303:308	arg1	aspects					261:267	three aspects	255:267	three aspects of composition, starch structural orders, and kernel structure	255:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	6	6	contain	had	1121:1123	arg1	structure					1111:1119	the kernel structure	1100:1119	the kernel structure	1100:1119	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	6	6	contain	had	1121:1123	arg2	influence					1136:1144	a critical influence	1125:1144	a critical influence	1125:1144	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	1	7	theme	digestive	210:218	arg1	properties					220:229	the low starch digestive properties	195:229	the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure	195:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	0	8	theme	in	81:82	arg1	digestion					90:98	in vitro digestion	81:98	in vitro digestion of highland barley	81:117	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	0	9	from	Effects	0:6	arg1	starch					74:79	starch	74:79	starch	74:79	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	1	10	from	aspects	261:267	arg1	properties					220:229	the low starch digestive properties	195:229	the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure	195:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	1	10	from	aspects	261:267	arg1	barley					243:248	highland barley	234:248	highland barley from three aspects of composition, starch structural orders, and kernel structure	234:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	4	11	theme	chyme	786:790	arg1	varieties					773:781	All varieties	769:781	All varieties of chyme	769:790	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	4	11	theme	chyme	786:790	arg1	chyme					786:790	chyme	786:790	chyme	786:790	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	0	12	dep	digestion	90:98	arg1	Effects					0:6	Effects	0:6	Effects of composition, starch structural orders, and kernel structure on starch	0:79	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	5	13	theme	kernel	957:962	arg1	analysis					975:982	kernel structural analysis	957:982	kernel structural analysis	957:982	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	2	14	theme	properties	470:479	arg1	contribution					439:450	the contribution	435:450	the contribution of these inherent properties to starch digestion under different physical forms	435:530	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	4	15	theme	blue	860:863	arg1	chyme					881:885	blue highland barley chyme	860:885	blue highland barley chyme	860:885	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	2	16	theme	inherent	461:468	arg1	properties					470:479	these inherent properties	455:479	these inherent properties	455:479	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	1	17	theme	kernel	315:320	arg1	structure					322:330	kernel structure	315:330	kernel structure	315:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	4	18	theme	lower	805:809	arg1	digestibility					818:830	lower starch digestibility	805:830	lower starch digestibility	805:830	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	0	19	dep	in	81:82	arg1	vitro					84:88	vitro	84:88	vitro	84:88	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	2	20	theme	digestive	337:345	arg1	systems					347:353	Two digestive systems	333:353	Two digestive systems	333:353	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	2	21	theme	chyme	407:411	arg1	forms					413:417	flour and chyme forms	397:417	flour and chyme forms	397:417	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	1	22	theme	structure	322:330	arg1	aspects					261:267	three aspects	255:267	three aspects of composition, starch structural orders, and kernel structure	255:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	3	23	theme	structural	680:689	arg1	order					691:695	short-range structural order	668:695	short-range structural order	668:695	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	5	24	theme	structural	964:973	arg1	analysis					975:982	kernel structural analysis	957:982	kernel structural analysis	957:982	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	1	25	theme	used	146:149	arg1	varieties					151:159	the widely used varieties	135:159	the widely used varieties in China	135:168	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	2	26	theme	flour	397:401	arg1	forms					413:417	flour and chyme forms	397:417	flour and chyme forms	397:417	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	1	27	theme	highland	234:241	arg1	barley					243:248	highland barley	234:248	highland barley from three aspects of composition, starch structural orders, and kernel structure	234:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	4	28	theme	starch	811:816	arg1	digestibility					818:830	lower starch digestibility	805:830	lower starch digestibility	805:830	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	5	29	theme	highland	1005:1012	arg1	structure					1028:1036	the blue highland barley kernel structure	996:1036	the blue highland barley kernel structure	996:1036	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	1	30	theme	barley	243:248	arg1	properties					220:229	the low starch digestive properties	195:229	the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure	195:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	0	31	theme	highland	103:110	arg1	barley					112:117	highland barley	103:117	highland barley	103:117	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	5	32	theme	blue	1000:1003	arg1	structure					1028:1036	the blue highland barley kernel structure	996:1036	the blue highland barley kernel structure	996:1036	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	6	33	theme	critical	1127:1134	arg1	influence					1136:1144	a critical influence	1125:1144	a critical influence	1125:1144	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	2	34	theme	highland	378:385	arg1	barley					387:392	highland barley	378:392	highland barley in flour and chyme forms	378:417	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	0	35	theme	composition	11:21	arg1	Effects					0:6	Effects	0:6	Effects of composition, starch structural orders, and kernel structure on starch	0:79	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	4	36	theme	barley	874:879	arg1	chyme					881:885	blue highland barley chyme	860:885	blue highland barley chyme	860:885	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	3	37	theme	poor	602:605	arg1	composition					616:626	poor chemical composition	602:626	poor chemical composition	602:626	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	6	38	theme	barley	1186:1191	arg1	digestibility					1160:1172	the starch digestibility	1149:1172	the starch digestibility of highland barley	1149:1191	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	0	39	theme	structural	31:40	arg1	orders					42:47	starch structural orders	24:47	starch structural orders	24:47	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	3	40	dep	higher	661:666	arg1	order					691:695	short-range structural order	668:695	short-range structural order	668:695	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	3	41	theme	chemical	607:614	arg1	composition					616:626	poor chemical composition	602:626	poor chemical composition	602:626	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	0	42	theme	starch	24:29	arg1	orders					42:47	starch structural orders	24:47	starch structural orders	24:47	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	0	43	theme	barley	112:117	arg1	digestion					90:98	in vitro digestion	81:98	in vitro digestion of highland barley	81:117	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	3	44	theme	black	557:561	arg1	barley					572:577	white and black highland barley	547:577	white and black highland barley	547:577	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	2	45	theme	starch	484:489	arg1	digestion					491:499	starch digestion	484:499	starch digestion under different physical forms	484:530	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	4	46	theme	starch	905:910	arg1	digestibility					912:924	much lower starch digestibility	894:924	much lower starch digestibility	894:924	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	3	47	theme	starch	713:718	arg1	higher					761:766	higher	761:766	higher	761:766	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	3	47	theme	starch	713:718	arg1	digestibility					720:732	the starch digestibility	709:732	the starch digestibility as flour	709:741	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	2	48	from	barley	387:392	arg1	forms					413:417	flour and chyme forms	397:417	flour and chyme forms	397:417	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	3	49	theme	short-range	668:678	arg1	order					691:695	short-range structural order	668:695	short-range structural order	668:695	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	0	50	theme	orders	42:47	arg1	Effects					0:6	Effects	0:6	Effects of composition, starch structural orders, and kernel structure on starch	0:79	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	1	51	theme	composition	272:282	arg1	aspects					261:267	three aspects	255:267	three aspects of composition, starch structural orders, and kernel structure	255:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	1	52	from	properties	220:229	arg1	aspects					261:267	three aspects	255:267	three aspects of composition, starch structural orders, and kernel structure	255:330	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	3	53	theme	lower	629:633	arg1	crystallinity					642:654	lower starch crystallinity	629:654	lower starch crystallinity	629:654	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	3	54	theme	white	547:551	arg1	barley					572:577	white and black highland barley	547:577	white and black highland barley	547:577	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	4	55	theme	highland	865:872	arg1	chyme					881:885	blue highland barley chyme	860:885	blue highland barley chyme	860:885	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	3	56	theme	starch	635:640	arg1	crystallinity					642:654	lower starch crystallinity	629:654	lower starch crystallinity	629:654	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	6	57	theme	kernel	1104:1109	arg1	structure					1111:1119	the kernel structure	1100:1119	the kernel structure	1100:1119	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	2	58	theme	physical	517:524	arg1	forms					526:530	different physical forms	507:530	different physical forms	507:530	Two digestive systems were constructed, with highland barley in flour and chyme forms, to investigate the contribution of these inherent properties to starch digestion under different physical forms.					
36436847	5	59	theme	kernel	1021:1026	arg1	structure					1028:1036	the blue highland barley kernel structure	996:1036	the blue highland barley kernel structure	996:1036	Furthermore, kernel structural analysis showed that the blue highland barley kernel structure effectively inhibited digestion.					
36436847	3	60	theme	blue	580:583	arg1	varieties					585:593	blue varieties	580:593	blue varieties	580:593	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	0	61	theme	kernel	54:59	arg1	structure					61:69	kernel structure	54:69	kernel structure	54:69	Effects of composition, starch structural orders, and kernel structure on starch in vitro digestion of highland barley.					
36436847	3	62	theme	highland	563:570	arg1	barley					572:577	white and black highland barley	547:577	white and black highland barley	547:577	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	1	63	from	varieties	151:159	arg1	China					164:168	China	164:168	China	164:168	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	6	64	theme	starch	1153:1158	arg1	digestibility					1160:1172	the starch digestibility	1149:1172	the starch digestibility of highland barley	1149:1191	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	4	65	theme	other	931:935	arg1	chyme					937:941	other chyme	931:941	other chyme	931:941	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
36436847	1	66	theme	starch	285:290	arg1	orders					303:308	starch structural orders	285:308	starch structural orders	285:308	In this study, the widely used varieties in China were selected to explore the low starch digestive properties of highland barley from three aspects of composition, starch structural orders, and kernel structure.					
36436847	6	67	theme	highland	1177:1184	arg1	barley					1186:1191	highland barley	1177:1191	highland barley	1177:1191	These results indicated that the kernel structure had a critical influence on the starch digestibility of highland barley.					
36436847	3	68	theme	higher	661:666	arg1	degree					697:702	higher short-range structural order degree	661:702	higher short-range structural order degree	661:702	Compared with white and black highland barley, blue varieties showed poor chemical composition, lower starch crystallinity, and higher short-range structural order degree, but the starch digestibility as flour was only slightly higher.					
36436847	4	69	theme	lower	899:903	arg1	digestibility					912:924	much lower starch digestibility	894:924	much lower starch digestibility	894:924	All varieties of chyme demonstrated lower starch digestibility compared to flour; however, blue highland barley chyme showed much lower starch digestibility than other chyme.					
35998858	1	0	theme	ways	146:149	arg1	one					125:127	one	125:127	one	125:127	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	1	0	theme	ways	146:149	arg1	ways					146:149	the important ways	132:149	the important ways	132:149	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	1	0	theme	ways	146:149	arg1	promotion					80:88	The promotion	76:88	The promotion of cellulose-based paper straws	76:120	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	2	1	theme	development	473:483	arg1	process					485:491	the development process	469:491	the development process	469:491	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	6	2	theme	wet	1074:1076	arg1	conditions					1078:1087	wet conditions	1074:1087	wet conditions	1074:1087	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	2	3	theme	physical	337:344	arg1	problems					355:362	physical strength problems	337:362	physical strength problems	337:362	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	7	4	theme	green	1339:1343	arg1	concept					1357:1363	the global green development concept	1328:1363	the global green development concept	1328:1363	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	6	5	theme	tensile	1144:1150	arg1	strength					1152:1159	excellent wet tensile strength	1130:1159	excellent wet tensile strength	1130:1159	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	3	6	theme	superhydrophobic	527:542	arg1	CFS					551:553	CFS	551:553	CFS	551:553	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	6	theme	superhydrophobic	527:542	arg1	straw					544:548	a new all-natural superhydrophobic straw	509:548	a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid	509:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	2	7	dep	stability	323:331	arg1	the					309:311	the	309:311	the	309:311	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	6	8	theme	wet	1140:1142	arg1	strength					1152:1159	excellent wet tensile strength	1130:1159	excellent wet tensile strength	1130:1159	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	2	9	from	challenge	456:464	arg1	process					485:491	the development process	469:491	the development process	469:491	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	7	10	theme	cellulose-based	1415:1429	arg1	materials					1431:1439	cellulose-based materials	1415:1439	cellulose-based materials	1415:1439	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	2	11	theme	strength	346:353	arg1	problems					355:362	physical strength problems	337:362	physical strength problems	337:362	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	5	12	theme	tensile	885:891	arg1	strength					893:900	tensile strength	885:900	tensile strength up to 67.15 MPa	885:916	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	13	theme	mechanical	864:873	arg1	strength					875:882	remarkable mechanical strength	853:882	remarkable mechanical strength (tensile strength up to 67.15 MPa)	853:917	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	6	14	theme	composite	1051:1059	arg1	straws					1061:1066	the composite straws	1047:1066	the composite straws under wet conditions	1047:1087	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	3	15	theme	new	511:513	arg1	CFS					551:553	CFS	551:553	CFS	551:553	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	15	theme	new	511:513	arg1	straw					544:548	a new all-natural superhydrophobic straw	509:548	a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid	509:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	5	16	theme	contact	823:829	arg1	angle					831:835	water contact angle	817:835	water contact angle up to 153°	817:846	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	17	theme	remarkable	853:862	arg1	strength					875:882	remarkable mechanical strength	853:882	remarkable mechanical strength (tensile strength up to 67.15 MPa)	853:917	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	3	18	theme	all-natural	515:525	arg1	CFS					551:553	CFS	551:553	CFS	551:553	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	18	theme	all-natural	515:525	arg1	straw					544:548	a new all-natural superhydrophobic straw	509:548	a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid	509:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	2	19	theme	inherent	378:385	arg1	hydrophilicity					387:400	the inherent hydrophilicity	374:400	the inherent hydrophilicity of the raw material cellulose	374:430	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	4	20	attach	derived	672:678	arg1	plant					685:689	plant	685:689	plant	685:689	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	20	attach	derived	672:678	arg2	acid					641:644	Stearic acid	633:644	Stearic acid	633:644	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	20	attach	derived	672:678	arg1	animal					695:700	animal	695:700	animal	695:700	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	20	attach	derived	672:678	arg2	acid					667:670	a saturated fatty acid	649:670	a saturated fatty acid derived from plant and animal oils	649:705	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	5	21	with	straw	780:784	arg1	strength					875:882	remarkable mechanical strength	853:882	remarkable mechanical strength (tensile strength up to 67.15 MPa)	853:917	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	21	with	straw	780:784	arg1	superhydrophobicity					796:814	superhydrophobicity	796:814	superhydrophobicity (water contact angle up to 153°)	796:847	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	7	22	theme	non-renewable	1294:1306	arg1	products					1308:1315	non-renewable products	1294:1315	non-renewable products	1294:1315	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	5	23	theme	green	774:778	arg1	straw					780:784	a green straw	772:784	a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa)	772:917	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	6	24	theme	paper	1184:1188	arg1	straws					1190:1195	commercial paper straws	1173:1195	commercial paper straws	1173:1195	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	6	25	theme	excellent	1130:1138	arg1	strength					1152:1159	excellent wet tensile strength	1130:1159	excellent wet tensile strength	1130:1159	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	7	26	theme	products	1308:1315	arg1	defects					1283:1289	the defects	1279:1289	the defects of non-renewable products	1279:1315	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	7	27	theme	development	1345:1355	arg1	concept					1357:1363	the global green development concept	1328:1363	the global green development concept	1328:1363	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	5	28	theme	hydrophobic	952:962	arg1	conditions					977:986	the hydrophobic modification conditions	948:986	the hydrophobic modification conditions of stearic acid	948:1002	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	29	theme	acid	999:1002	arg1	conditions					977:986	the hydrophobic modification conditions	948:986	the hydrophobic modification conditions of stearic acid	948:1002	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	1	30	theme	cellulose-based	93:107	arg1	straws					115:120	cellulose-based paper straws	93:120	cellulose-based paper straws	93:120	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	2	31	theme	material	413:420	arg1	cellulose					422:430	the raw material cellulose	405:430	the raw material cellulose	405:430	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	2	32	theme	cellulose	422:430	arg1	hydrophilicity					387:400	the inherent hydrophilicity	374:400	the inherent hydrophilicity of the raw material cellulose	374:430	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	6	33	contain	had	1089:1091	arg2	absorption					1105:1114	lower water absorption	1093:1114	lower water absorption	1093:1114	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	6	33	contain	had	1089:1091	arg1	straws					1061:1066	the composite straws	1047:1066	the composite straws under wet conditions	1047:1087	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	1	34	theme	paper	109:113	arg1	straws					115:120	cellulose-based paper straws	93:120	cellulose-based paper straws	93:120	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	2	35	theme	raw	409:411	arg1	cellulose					422:430	the raw material cellulose	405:430	the raw material cellulose	405:430	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	5	36	theme	sugarcane	751:759	arg1	peel					766:769	sugarcane cane peel	751:769	sugarcane cane peel	751:769	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	7	37	theme	binders	1264:1270	arg1	addition					1243:1250	the addition	1239:1250	the addition of chemical binders	1239:1270	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	6	38	theme	commercial	1173:1182	arg1	straws					1190:1195	commercial paper straws	1173:1195	commercial paper straws	1173:1195	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	5	39	theme	cane	761:764	arg1	peel					766:769	sugarcane cane peel	751:769	sugarcane cane peel	751:769	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	3	40	theme	acid	612:615	arg1	composite					566:574	a composite	564:574	a composite of cellulose nanofibers and stearic acid	564:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	40	theme	acid	612:615	arg1	nanofibers					589:598	cellulose nanofibers	579:598	cellulose nanofibers	579:598	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	40	theme	acid	612:615	arg1	acid					612:615	stearic acid	604:615	stearic acid	604:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	5	41	theme	water	817:821	arg1	angle					831:835	water contact angle	817:835	water contact angle up to 153°	817:846	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	42	theme	peel	766:769	arg1	hydrophobicity					733:746	the specific hydrophobicity	720:746	the specific hydrophobicity of sugarcane cane peel	720:769	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	43	theme	specific	724:731	arg1	hydrophobicity					733:746	the specific hydrophobicity	720:746	the specific hydrophobicity of sugarcane cane peel	720:769	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	44	theme	stearic	991:997	arg1	acid					999:1002	stearic acid	991:1002	stearic acid	991:1002	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	7	45	theme	materials	1431:1439	arg1	development					1400:1410	the development	1396:1410	the development of cellulose-based materials	1396:1439	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	1	46	theme	straws	115:120	arg1	one					125:127	one	125:127	one	125:127	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	1	46	theme	straws	115:120	arg1	ways					146:149	the important ways	132:149	the important ways	132:149	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	1	46	theme	straws	115:120	arg1	promotion					80:88	The promotion	76:88	The promotion of cellulose-based paper straws	76:120	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	2	47	theme	important	446:454	arg1	challenge					456:464	an important challenge	443:464	an important challenge in the development process	443:491	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	2	48	theme	composite	208:216	arg1	straws					218:223	composite straws	208:223	composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose	208:430	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	7	49	theme	chemical	1255:1262	arg1	binders					1264:1270	chemical binders	1255:1270	chemical binders	1255:1270	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	6	50	theme	water	1099:1103	arg1	absorption					1105:1114	lower water absorption	1093:1114	lower water absorption	1093:1114	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	5	51	theme	modification	964:975	arg1	conditions					977:986	the hydrophobic modification conditions	948:986	the hydrophobic modification conditions of stearic acid	948:1002	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	52	theme	solvent	1012:1018	arg1	vaporization					1020:1031	solvent vaporization	1012:1031	solvent vaporization	1012:1031	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	0	53	dep	strong	15:20	arg1	all-natural					23:33	all-natural	23:33	all-natural	23:33	A bioinspired, strong, all-natural, superhydrophobic cellulose-based straw.					
35998858	4	54	theme	saturated	651:659	arg1	acid					667:670	a saturated fatty acid	649:670	a saturated fatty acid derived from plant and animal oils	649:705	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	54	theme	saturated	651:659	arg1	acid					641:644	Stearic acid	633:644	Stearic acid	633:644	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	2	55	theme	water	317:321	arg1	stability					323:331	low water stability	313:331	low water stability	313:331	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	4	56	dep	plant	685:689	arg1	oils					702:705	oils	702:705	oils	702:705	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	7	57	theme	new	1377:1379	arg1	strategies					1381:1390	new strategies	1377:1390	new strategies for the development of cellulose-based materials	1377:1439	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	5	58	dep	strength	875:882	arg1	strength					893:900	tensile strength	885:900	tensile strength up to 67.15 MPa	885:916	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	5	59	dep	superhydrophobicity	796:814	arg1	angle					831:835	water contact angle	817:835	water contact angle up to 153°	817:846	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	3	60	theme	stearic	604:610	arg1	acid					612:615	stearic acid	604:615	stearic acid	604:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	2	61	theme	low	313:315	arg1	stability					323:331	low water stability	313:331	low water stability	313:331	However, developing composite straws that are simultaneously highly biocompatible, safe, and non-toxic and that overcome the low water stability and physical strength problems caused by the inherent hydrophilicity of the raw material cellulose has become an important challenge in the development process.					
35998858	6	62	theme	lower	1093:1097	arg1	absorption					1105:1114	lower water absorption	1093:1114	lower water absorption	1093:1114	Furthermore, the composite straws under wet conditions had lower water absorption and exhibited excellent wet tensile strength compared to commercial paper straws.					
35998858	5	63	dep	153°	843:846	arg1	to					840:841	to	840:841	to	840:841	Inspired by the specific hydrophobicity of sugarcane cane peel, a green straw with both superhydrophobicity (water contact angle up to 153°) and remarkable mechanical strength (tensile strength up to 67.15 MPa) was developed by controlling the hydrophobic modification conditions of stearic acid through solvent vaporization.					
35998858	3	64	theme	cellulose	579:587	arg1	nanofibers					589:598	cellulose nanofibers	579:598	cellulose nanofibers	579:598	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	4	65	theme	fatty	661:665	arg1	acid					667:670	a saturated fatty acid	649:670	a saturated fatty acid derived from plant and animal oils	649:705	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	65	theme	fatty	661:665	arg1	acid					641:644	Stearic acid	633:644	Stearic acid	633:644	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	66	theme	Stearic	633:639	arg1	acid					667:670	a saturated fatty acid	649:670	a saturated fatty acid derived from plant and animal oils	649:705	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	4	66	theme	Stearic	633:639	arg1	acid					641:644	Stearic acid	633:644	Stearic acid	633:644	Stearic acid is a saturated fatty acid derived from plant and animal oils.					
35998858	0	67	theme	cellulose-based	53:67	arg1	straw					69:73	cellulose-based straw	53:73	cellulose-based straw	53:73	A bioinspired, strong, all-natural, superhydrophobic cellulose-based straw.					
35998858	7	68	theme	global	1332:1337	arg1	concept					1357:1363	the global green development concept	1328:1363	the global green development concept	1328:1363	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35998858	3	69	theme	nanofibers	589:598	arg1	composite					566:574	a composite	564:574	a composite of cellulose nanofibers and stearic acid	564:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	69	theme	nanofibers	589:598	arg1	nanofibers					589:598	cellulose nanofibers	579:598	cellulose nanofibers	579:598	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	3	69	theme	nanofibers	589:598	arg1	acid					612:615	stearic acid	604:615	stearic acid	604:615	In this study, a new all-natural superhydrophobic straw (CFS) made of a composite of cellulose nanofibers and stearic acid was introduced.					
35998858	1	70	theme	important	136:144	arg1	ways					146:149	the important ways	132:149	the important ways	132:149	The promotion of cellulose-based paper straws is one of the important ways to improve white pollution nowadays.					
35998858	7	71	theme	composite	1215:1223	arg1	straw					1225:1229	the composite straw	1211:1229	the composite straw without the addition of chemical binders	1211:1270	In addition, the composite straw without the addition of chemical binders avoids the defects of non-renewable products, fits into the global green development concept, and brings new strategies for the development of cellulose-based materials.					
35277009	3	0	from	tumorigenesis	478:490	arg1	model					503:507	a mouse model	495:507	a mouse model of colorectal cancer	495:528	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	1	1	theme	milk	164:167	arg1	lactose					175:181	the milk sugar lactose	160:181	the milk sugar lactose	160:181	Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes.					
35277009	10	2	theme	lactulose	1297:1305	arg1	treatment					1307:1315	lactulose treatment	1297:1315	lactulose treatment	1297:1315	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	4	3	theme	/dextran	601:608	arg1	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	1	4	theme	sugar	169:173	arg1	lactose					175:181	the milk sugar lactose	160:181	the milk sugar lactose	160:181	Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes.					
35277009	5	5	theme	Lactulose	661:669	arg1	treatment					671:679	Lactulose treatment	661:679	Lactulose treatment	661:679	Lactulose treatment was performed by feeding 2% lactulose for 14 weeks.					
35277009	3	6	theme	microbiota	559:568	arg1	composition					570:580	gut microbiota composition	555:580	gut microbiota composition	555:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	4	7	used	used	641:644	arg2	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	4	8	theme	sodium	618:623	arg1	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	6	9	theme	Stool	733:737	arg1	samples					739:745	Stool samples	733:745	Stool samples collected at 4 time points	733:772	Stool samples collected at 4 time points were used for metagenomic analysis of the microbiota.					
35277009	6	10	theme	metagenomic	788:798	arg1	analysis					800:807	metagenomic analysis	788:807	metagenomic analysis of the microbiota	788:825	Stool samples collected at 4 time points were used for metagenomic analysis of the microbiota.					
35277009	4	11	theme	sulfate	610:616	arg1	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	3	12	theme	present	353:359	arg1	study					361:365	the present study	349:365	the present study	349:365	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	8	13	from	imbalance	999:1007	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	8	14	theme	pathogen	1066:1073	arg1	abundance					1075:1083	increased pathogen abundance	1056:1083	increased pathogen abundance (e.g., Escherichia and Clostridium)	1056:1119	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	3	15	from	effect	545:550	arg1	tumorigenesis					478:490	inflammation-related tumorigenesis	457:490	inflammation-related tumorigenesis	457:490	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	15	from	effect	545:550	arg1	inflammation					440:451	gastrointestinal inflammation	423:451	gastrointestinal inflammation	423:451	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	15	from	effect	545:550	arg1	composition					570:580	gut microbiota composition	555:580	gut microbiota composition	555:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	11	16	theme	lactulose	1499:1507	arg1	treatment					1509:1517	lactulose treatment	1499:1517	lactulose treatment	1499:1517	Meanwhile, the pathways related to Crohn's disease were downregulated after lactulose treatment.					
35277009	3	17	theme	inflammation-related	457:476	arg1	tumorigenesis					478:490	inflammation-related tumorigenesis	457:490	inflammation-related tumorigenesis	457:490	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	0	18	theme	Microbiota	41:50	arg1	Structure					24:32	the Structure	20:32	the Structure of Gut Microbiota	20:50	Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis.					
35277009	8	19	theme	increased	1056:1064	arg1	abundance					1075:1083	increased pathogen abundance	1056:1083	increased pathogen abundance (e.g., Escherichia and Clostridium)	1056:1119	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	7	20	dep	weeks	867:871	arg1	injection					883:891	AOM injection	879:891	AOM injection	879:891	Pathological analysis was performed 21 weeks after AOM injection.					
35277009	3	21	theme	gut	555:557	arg1	composition					570:580	gut microbiota composition	555:580	gut microbiota composition	555:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	22	theme	therapeutic	388:398	arg1	effect					400:405	the therapeutic effect	384:405	the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition	384:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	23	from	effect	400:405	arg1	composition					570:580	gut microbiota composition	555:580	gut microbiota composition	555:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	23	from	effect	400:405	arg1	inflammation					440:451	gastrointestinal inflammation	423:451	gastrointestinal inflammation	423:451	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	23	from	effect	400:405	arg1	tumorigenesis					478:490	inflammation-related tumorigenesis	457:490	inflammation-related tumorigenesis	457:490	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	2	24	theme	bowel	331:335	arg1	disease					337:343	inflammatory bowel disease	318:343	inflammatory bowel disease	318:343	Lactulose is proposed to modulate gut microbiota and thus expected to be beneficial in treating inflammatory bowel disease.					
35277009	8	25	from	counts	927:932	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	4	26	theme	Azoxymethane	583:594	arg1	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	2	27	theme	inflammatory	318:329	arg1	disease					337:343	inflammatory bowel disease	318:343	inflammatory bowel disease	318:343	Lactulose is proposed to modulate gut microbiota and thus expected to be beneficial in treating inflammatory bowel disease.					
35277009	6	28	used	used	779:782	arg2	samples					739:745	Stool samples	733:745	Stool samples collected at 4 time points	733:772	Stool samples collected at 4 time points were used for metagenomic analysis of the microbiota.					
35277009	5	29	theme	2	706:706	arg1	%					707:707	%	707:707	%	707:707	Lactulose treatment was performed by feeding 2% lactulose for 14 weeks.					
35277009	6	30	theme	time	762:765	arg1	points					767:772	4 time points	760:772	4 time points	760:772	Stool samples collected at 4 time points were used for metagenomic analysis of the microbiota.					
35277009	7	31	theme	Pathological	828:839	arg1	analysis					841:848	Pathological analysis	828:848	Pathological analysis	828:848	Pathological analysis was performed 21 weeks after AOM injection.					
35277009	3	32	theme	mouse	497:501	arg1	model					503:507	a mouse model	495:507	a mouse model of colorectal cancer	495:528	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	8	33	from	tumorigenesis	980:992	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	5	34	theme	%	707:707	arg1	lactulose					709:717	2% lactulose	706:717	2% lactulose for 14 weeks	706:730	Lactulose treatment was performed by feeding 2% lactulose for 14 weeks.					
35277009	1	35	theme	galactose-fructose	114:131	arg1	disaccharide					133:144	a galactose-fructose disaccharide	112:144	a galactose-fructose disaccharide	112:144	Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes.					
35277009	1	35	theme	galactose-fructose	114:131	arg1	Lactulose					101:109	Lactulose	101:109	Lactulose	101:109	Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes.					
35277009	0	36	theme	Gut	37:39	arg1	Microbiota					41:50	Gut Microbiota	37:50	Gut Microbiota	37:50	Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis.					
35277009	1	37	dep	heating	186:192	arg1	processes					211:219	processes	211:219	processes	211:219	Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes.					
35277009	10	38	theme	pathogen	1340:1347	arg1	abundance					1349:1357	pathogen abundance	1340:1357	pathogen abundance	1340:1357	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	8	39	from	expression	957:966	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	3	40	theme	gastrointestinal	423:438	arg1	inflammation					440:451	gastrointestinal inflammation	423:451	gastrointestinal inflammation	423:451	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	10	41	theme	Muribaculum	1390:1400	arg1	abundance					1377:1385	the abundance	1373:1385	the abundance of Muribaculum and Lachnospiraceae	1373:1420	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	12	42	theme	inflammatory	1664:1675	arg1	tumorigenesis					1677:1689	inflammatory tumorigenesis	1664:1689	inflammatory tumorigenesis	1664:1689	Our findings suggest that lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis.					
35277009	11	43	theme	related	1447:1453	arg1	pathways					1438:1445	the pathways	1434:1445	the pathways related to Crohn's disease	1434:1472	Meanwhile, the pathways related to Crohn's disease were downregulated after lactulose treatment.					
35277009	11	43	theme	related	1447:1453	arg1	Meanwhile					1423:1431	Meanwhile	1423:1431	Meanwhile	1423:1431	Meanwhile, the pathways related to Crohn's disease were downregulated after lactulose treatment.					
35277009	8	44	theme	macrophage	916:925	arg1	counts					927:932	the macrophage counts	912:932	the macrophage counts	912:932	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	3	45	theme	cancer	523:528	arg1	model					503:507	a mouse model	495:507	a mouse model of colorectal cancer	495:528	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	46	theme	lactulose	410:418	arg1	effect					400:405	the therapeutic effect	384:405	the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition	384:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	46	theme	lactulose	410:418	arg1	effect					545:550	its effect	541:550	the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition	384:580	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	8	47	theme	inflammatory	935:946	arg1	expression					957:966	inflammatory cytokine expression	935:966	inflammatory cytokine expression	935:966	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	12	48	dep	structure	1569:1577	arg1	the					1565:1567	the	1565:1567	the	1565:1567	Our findings suggest that lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis.					
35277009	8	49	theme	microbiota	1016:1025	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	8	50	theme	gut	1012:1014	arg1	composition					1027:1037	gut microbiota composition	1012:1037	gut microbiota composition	1012:1037	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	12	51	theme	microbiota	1613:1622	arg1	structure					1569:1577	structure	1569:1577	structure	1569:1577	Our findings suggest that lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis.					
35277009	12	51	theme	microbiota	1613:1622	arg1	composition					1583:1593	composition	1583:1593	composition	1583:1593	Our findings suggest that lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis.					
35277009	9	52	theme	inflammatory	1160:1171	arg1	events					1173:1178	the inflammatory events	1156:1178	the inflammatory events	1156:1178	Lactulose significantly inhibited the inflammatory events, and ameliorated inflammation and tumorigenesis.					
35277009	10	53	theme	Lachnospiraceae	1406:1420	arg1	abundance					1377:1385	the abundance	1373:1385	the abundance of Muribaculum and Lachnospiraceae	1373:1420	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	4	54	theme	DSS	626:628	arg1	model					631:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model	583:635	Azoxymethane (AOM)/dextran sulfate sodium (DSS) model was used in this study.					
35277009	6	55	theme	microbiota	816:825	arg1	analysis					800:807	metagenomic analysis	788:807	metagenomic analysis of the microbiota	788:825	Stool samples collected at 4 time points were used for metagenomic analysis of the microbiota.					
35277009	3	56	from	inflammation	440:451	arg1	model					503:507	a mouse model	495:507	a mouse model of colorectal cancer	495:528	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	3	57	theme	colorectal	512:521	arg1	cancer					523:528	colorectal cancer	512:528	colorectal cancer	512:528	In the present study, we investigated the therapeutic effect of lactulose on gastrointestinal inflammation and inflammation-related tumorigenesis in a mouse model of colorectal cancer as well as its effect on gut microbiota composition.					
35277009	10	58	theme	microbiota	1263:1272	arg1	composition					1233:1243	The composition	1229:1243	The composition of the intestinal microbiota	1229:1272	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	0	59	theme	Colitis-Associated	67:84	arg1	Tumorigenesis					86:98	Colitis-Associated Tumorigenesis	67:98	Colitis-Associated Tumorigenesis	67:98	Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis.					
35277009	12	60	theme	intestinal	1602:1611	arg1	microbiota					1613:1622	the intestinal microbiota	1598:1622	the intestinal microbiota	1598:1622	Our findings suggest that lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis.					
35277009	8	61	theme	cytokine	948:955	arg1	expression					957:966	inflammatory cytokine expression	935:966	inflammatory cytokine expression	935:966	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	10	62	theme	intestinal	1252:1261	arg1	microbiota					1263:1272	the intestinal microbiota	1248:1272	the intestinal microbiota	1248:1272	The composition of the intestinal microbiota was also restored upon lactulose treatment, and lactulose reduced pathogen abundance and increased the abundance of Muribaculum and Lachnospiraceae.					
35277009	8	63	dep	abundance	1075:1083	arg1	Escherichia					1092:1102	Escherichia	1092:1102	Escherichia	1092:1102	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	8	63	dep	abundance	1075:1083	arg1	e.g.					1086:1089	e.g.	1086:1089	e.g.	1086:1089	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	8	63	dep	abundance	1075:1083	arg1	Clostridium					1108:1118	Clostridium	1108:1118	Clostridium	1108:1118	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	2	64	theme	gut	256:258	arg1	microbiota					260:269	gut microbiota	256:269	gut microbiota	256:269	Lactulose is proposed to modulate gut microbiota and thus expected to be beneficial in treating inflammatory bowel disease.					
35277009	8	65	theme	colorectal	969:978	arg1	tumorigenesis					980:992	colorectal tumorigenesis	969:992	colorectal tumorigenesis	969:992	AOM/DSS increased the macrophage counts, inflammatory cytokine expression, colorectal tumorigenesis, and imbalance in gut microbiota composition, as evidenced by increased pathogen abundance (e.g., Escherichia and Clostridium).					
35277009	7	66	theme	AOM	879:881	arg1	injection					883:891	AOM injection	879:891	AOM injection	879:891	Pathological analysis was performed 21 weeks after AOM injection.					
37364964	7	0	theme	thiazolidine	1564:1575	arg1	chemistry					1577:1585	thiazolidine chemistry	1564:1585	thiazolidine chemistry	1564:1585	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	2	1	theme	coupling	378:385	arg1	reactions					387:395	coupling reactions	378:395	coupling reactions	378:395	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
37364964	7	2	theme	proposed	1505:1512	arg1	approach					1514:1521	the proposed approach	1501:1521	the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications	1501:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	5	3	theme	reversible	877:886	arg1	intermediate					896:907	The reversible kinetic intermediate	873:907	The reversible kinetic intermediate	873:907	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	6	4	theme	further	1434:1440	arg1	proliferation					1442:1454	further proliferation	1434:1454	further proliferation	1434:1454	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	1	5	theme	stable	180:185	arg1	hydrogels					187:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	7	6	theme	coupling	1614:1621	arg1	technique					1623:1631	a general coupling technique	1604:1631	a general coupling technique for developing injectable and stable hydrogels for biomedical applications	1604:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	6	7	theme	mesenchymal	1312:1322	arg1	cells					1329:1333	the embedded mesenchymal stem cells	1299:1333	the embedded mesenchymal stem cells	1299:1333	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	6	8	theme	embedded	1303:1310	arg1	cells					1329:1333	the embedded mesenchymal stem cells	1299:1333	the embedded mesenchymal stem cells	1299:1333	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	3	9	dep	reversible	410:419	arg1	irreversible					424:435	irreversible	424:435	irreversible	424:435	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	3	9	dep	reversible	410:419	arg1	to					421:422	to	421:422	to	421:422	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	2	10	theme	different	311:319	arg1	stages					321:326	different stages	311:326	different stages	311:326	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
37364964	7	11	theme	"	1553:1553	arg1	approach					1514:1521	the proposed approach	1501:1521	the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications	1501:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	5	12	theme	irreversible	1048:1059	arg1	network					1075:1081	the irreversible thermodynamic network	1044:1081	the irreversible thermodynamic network	1044:1081	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	4	13	theme	aldehyde-functionalized	688:710	arg1	acid					723:726	aldehyde-functionalized hyaluronic acid	688:726	aldehyde-functionalized hyaluronic acid (SA-HA)	688:734	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	4	13	theme	aldehyde-functionalized	688:710	arg1	SA-HA					729:733	SA-HA	729:733	SA-HA	729:733	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	6	14	theme	Schiff	1181:1186	arg1	hydrogels					1193:1201	the Schiff base hydrogels	1177:1201	the Schiff base hydrogels	1177:1201	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	4	15	theme	cysteine-capped	740:754	arg1	DI-Cys					773:778	DI-Cys	773:778	DI-Cys	773:778	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	4	15	theme	cysteine-capped	740:754	arg1	ethylenediamine					756:770	cysteine-capped ethylenediamine	740:770	cysteine-capped ethylenediamine (DI-Cys)	740:779	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	3	16	theme	thiazolidine-based	454:471	arg1	reaction					487:494	a thiazolidine-based bioorthogonal reaction	452:494	a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability	452:620	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	5	17	theme	thiol-triggered	921:935	arg1	transition					948:957	thiol-triggered gel-to-sol transition	921:957	thiol-triggered gel-to-sol transition	921:957	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	3	18	from	aldehydes	524:532	arg1	conditions					551:560	physiological conditions	537:560	physiological conditions	537:560	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	2	19	theme	hydrogels	298:306	arg1	injectability					259:271	the injectability	255:271	the injectability	255:271	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
37364964	2	19	theme	hydrogels	298:306	arg1	stability					281:289	the stability	277:289	the stability of the hydrogels	277:306	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
37364964	6	20	theme	simple	1238:1243	arg1	concept					1260:1266	this simple, yet effective concept	1233:1266	this simple, yet effective concept awarded	1233:1274	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	3	21	theme	bioorthogonal	473:485	arg1	reaction					487:494	a thiazolidine-based bioorthogonal reaction	452:494	a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability	452:620	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	0	22	theme	facile	2:7	arg1	bioorthogonal					9:21	A facile bioorthogonal	0:21	A facile bioorthogonal	0:21	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	4	23	theme	reversible	820:829	arg1	crosslinking					846:857	reversible hemithioacetal crosslinking	820:857	reversible hemithioacetal crosslinking within 2 min	820:870	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	1	24	theme	great	202:206	arg1	promise					208:214	great promise	202:214	great promise for clinical applications	202:240	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	3	25	theme	reversible	410:419	arg1	concept					438:444	A distinct "reversible to irreversible" concept	398:444	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability	398:620	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	7	26	theme	injectable	1648:1657	arg1	hydrogels					1670:1678	injectable and stable hydrogels	1648:1678	injectable and stable hydrogels for biomedical applications	1648:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	4	27	dep	hydrogels	795:803	arg1	formed					805:810	formed	805:810	hydrogels formed through reversible hemithioacetal crosslinking within 2 min	795:870	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	7	28	dep	reversible	1527:1536	arg1	to					1538:1539	to	1538:1539	to	1538:1539	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	7	28	dep	reversible	1527:1536	arg1	irreversible					1541:1552	irreversible	1541:1552	irreversible	1541:1552	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	5	29	theme	gel-to-sol	937:946	arg1	transition					948:957	thiol-triggered gel-to-sol transition	921:957	thiol-triggered gel-to-sol transition	921:957	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	0	30	theme	hyaluronic	138:147	arg1	acid					149:152	hyaluronic acid	138:152	hyaluronic acid hydrogels	138:162	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	4	31	theme	hyaluronic	712:721	arg1	acid					723:726	aldehyde-functionalized hyaluronic acid	688:726	aldehyde-functionalized hyaluronic acid (SA-HA)	688:734	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	4	31	theme	hyaluronic	712:721	arg1	SA-HA					729:733	SA-HA	729:733	SA-HA	729:733	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	3	32	theme	distinct	400:407	arg1	concept					438:444	A distinct "reversible to irreversible" concept	398:444	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability	398:620	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	7	33	theme	biomedical	1684:1693	arg1	applications					1695:1706	biomedical applications	1684:1706	biomedical applications	1684:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	4	34	theme	hemithioacetal	831:844	arg1	crosslinking					846:857	reversible hemithioacetal crosslinking	820:857	reversible hemithioacetal crosslinking within 2 min	820:870	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	1	35	theme	clinical	220:227	arg1	applications					229:240	clinical applications	220:240	clinical applications	220:240	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	3	36	theme	"	436:436	arg1	concept					438:444	A distinct "reversible to irreversible" concept	398:444	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability	398:620	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	5	37	theme	thermodynamic	1061:1073	arg1	network					1075:1081	the irreversible thermodynamic network	1044:1081	the irreversible thermodynamic network	1044:1081	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	0	38	theme	hydrogels	154:162	arg1	injectability					107:119	injectability	107:119	injectability	107:119	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	0	38	theme	hydrogels	154:162	arg1	stability					125:133	stability	125:133	stability	125:133	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	0	39	theme	reversible	39:48	arg1	strategy					66:73	reversible to irreversible strategy	39:73	reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels	39:162	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	7	40	theme	general	1606:1612	arg1	technique					1623:1631	a general coupling technique	1604:1631	a general coupling technique for developing injectable and stable hydrogels for biomedical applications	1604:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	0	41	theme	acid	149:152	arg1	hydrogels					154:162	hyaluronic acid hydrogels	138:162	hyaluronic acid hydrogels	138:162	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	1	42	contain	have	197:200	arg1	hydrogels					187:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	1	42	contain	have	197:200	arg2	promise					208:214	great promise	202:214	great promise for clinical applications	202:240	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	7	43	theme	reversible	1527:1536	arg1	"					1553:1553	"reversible to irreversible"	1526:1553	"reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications	1526:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	4	44	theme	acid	723:726	arg1	solutions					675:683	aqueous solutions	667:683	aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys)	667:779	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	5	45	theme	hydrogel	1013:1020	arg1	injectability					979:991	injectability	979:991	injectability	979:991	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	5	45	theme	hydrogel	1013:1020	arg1	shear-thinning					960:973	shear-thinning	960:973	shear-thinning	960:973	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	5	45	theme	hydrogel	1013:1020	arg1	transition					948:957	thiol-triggered gel-to-sol transition	921:957	thiol-triggered gel-to-sol transition	921:957	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	3	46	theme	first	643:647	arg1	time					649:652	the first time	639:652	the first time	639:652	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	3	47	theme	physiological	537:549	arg1	conditions					551:560	physiological conditions	537:560	physiological conditions	537:560	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	0	48	dep	reversible	39:48	arg1	to					50:51	to	50:51	to	50:51	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	0	48	dep	reversible	39:48	arg1	irreversible					53:64	irreversible	53:64	irreversible	53:64	A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.					
37364964	3	49	from	1,2-aminothiols	504:518	arg1	conditions					551:560	physiological conditions	537:560	physiological conditions	537:560	A distinct "reversible to irreversible" concept using a thiazolidine-based bioorthogonal reaction between 1,2-aminothiols and aldehydes in physiological conditions to surmount the dilemma between injectability and stability is presented for the first time.					
37364964	2	50	theme	limited	360:366	arg1	number					368:373	the limited number	356:373	the limited number of coupling reactions	356:395	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
37364964	7	51	theme	stable	1663:1668	arg1	hydrogels					1670:1678	injectable and stable hydrogels	1648:1678	injectable and stable hydrogels for biomedical applications	1648:1706	There is potential for the proposed approach of "reversible to irreversible" based on thiazolidine chemistry to be applied as a general coupling technique for developing injectable and stable hydrogels for biomedical applications.					
37364964	5	52	theme	improved	1142:1149	arg1	stability					1151:1159	improved stability	1142:1159	improved stability	1142:1159	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	4	53	theme	ethylenediamine	756:770	arg1	solutions					675:683	aqueous solutions	667:683	aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys)	667:779	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	4	54	theme	aqueous	667:673	arg1	solutions					675:683	aqueous solutions	667:683	aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys)	667:779	Upon mixing aqueous solutions of aldehyde-functionalized hyaluronic acid (SA-HA) and cysteine-capped ethylenediamine (DI-Cys), SA-HA/DI-Cys hydrogels formed through reversible hemithioacetal crosslinking within 2 min.					
37364964	6	55	theme	stem	1324:1327	arg1	cells					1329:1333	the embedded mesenchymal stem cells	1299:1333	the embedded mesenchymal stem cells	1299:1333	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	5	56	with	gel	1133:1135	arg1	stability					1151:1159	improved stability	1142:1159	improved stability	1142:1159	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	1	57	theme	Injectable	165:174	arg1	hydrogels					187:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels	165:195	Injectable and stable hydrogels have great promise for clinical applications.					
37364964	6	58	theme	base	1188:1191	arg1	hydrogels					1193:1201	the Schiff base hydrogels	1177:1201	the Schiff base hydrogels	1177:1201	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	6	59	theme	effective	1250:1258	arg1	concept					1260:1266	this simple, yet effective concept	1233:1266	this simple, yet effective concept awarded	1233:1274	As compared to the Schiff base hydrogels, the hydrogels generated from this simple, yet effective concept awarded improved protection to the embedded mesenchymal stem cells and fibroblast during injection, retained the cells homogeneously within the gel, and allowed them further proliferation in vitro and in vivo.					
37364964	5	60	theme	SA-HA/DI-Cys	1000:1011	arg1	hydrogel					1013:1020	the SA-HA/DI-Cys hydrogel	996:1020	the SA-HA/DI-Cys hydrogel	996:1020	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	5	61	theme	resulting	1123:1131	arg1	gel					1133:1135	the resulting gel	1119:1135	the resulting gel with improved stability	1119:1159	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	5	62	theme	kinetic	888:894	arg1	intermediate					896:907	The reversible kinetic intermediate	873:907	The reversible kinetic intermediate	873:907	The reversible kinetic intermediate facilitated thiol-triggered gel-to-sol transition, shear-thinning and injectability of the SA-HA/DI-Cys hydrogel but then converted to the irreversible thermodynamic network after injection, thereby permitting the resulting gel with improved stability.					
37364964	2	63	theme	reactions	387:395	arg1	number					368:373	the limited number	356:373	the limited number of coupling reactions	356:395	Fine-tuning the injectability and the stability of the hydrogels at different stages has been challenging due to the limited number of coupling reactions.					
36152907	9	0	theme	maximum	1530:1536	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	0	theme	maximum	1530:1536	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	6	1	theme	hydrogels	817:825	arg1	properties					799:808	the mechanical and biological properties	769:808	the mechanical and biological properties of the hydrogels	769:825	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	2	2	theme	tissue	351:356	arg1	engineering					358:368	bone tissue engineering	346:368	bone tissue engineering	346:368	In this study, a self-healing and injectable polysaccharide-based hydrogel was prepared for bone tissue engineering.					
36152907	8	3	theme	%	1168:1168	arg1	HAp					1176:1178	6% (w/v) HAp and 10 mg/mL MHGMs	1167:1197	HAp	1176:1178	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	6	4	theme	drug-embedded	902:914	arg1	MHGMs					916:920	drug-embedded MHGMs	902:920	drug-embedded MHGMs	902:920	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	15	5	theme	drug	2720:2723	arg1	delivery					2725:2732	drug delivery	2720:2732	drug delivery	2720:2732	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	10	6	theme	drug	1627:1630	arg1	properties					1644:1653	good drug retardation properties	1622:1653	good drug retardation properties	1622:1653	In addition, this composite hydrogel showed good drug retardation properties and antibacterial effects against both S. aureus and E. coli.					
36152907	11	7	theme	smart	1863:1867	arg1	scaffold					1911:1918	an alternative scaffold	1896:1918	an alternative scaffold for drug delivery and bone regeneration	1896:1958	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	11	7	theme	smart	1863:1867	arg1	hydrogel					1869:1876	this smart hydrogel	1858:1876	this smart hydrogel	1858:1876	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	9	8	theme	%	1391:1391	arg1	decrease					1393:1400	a 65.6% decrease	1385:1400	a 65.6% decrease in swelling rate (39.4 to 13.6)	1385:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	120 s					1377:1381	120 s	1377:1381	120 s	1377:1381	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	mass					1455:1458	mass	1455:1458	mass residual after degradation (79.5 to 120.8%)	1455:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	rate					1414:1417	swelling rate	1405:1417	swelling rate (39.4 to 13.6)	1405:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	time					1364:1367	gelation time	1355:1367	gelation time (196 to 120 s)	1355:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	13.6					1428:1431	13.6	1428:1431	13.6	1428:1431	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	9	from	increase	1443:1450	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	5	10	theme	antibacterial	643:655	arg1	drugs					657:661	The antibacterial drugs	639:661	The antibacterial drugs	639:661	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	10	theme	antibacterial	643:655	arg1	hydrochloride					677:689	tetracycline hydrochloride	664:689	tetracycline hydrochloride (TH)	664:694	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	10	theme	antibacterial	643:655	arg1	sulfadiazine					707:718	silver sulfadiazine	700:718	silver sulfadiazine (AgSD)	700:725	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	6	11	theme	biological	788:797	arg1	properties					799:808	the mechanical and biological properties	769:808	the mechanical and biological properties of the hydrogels	769:825	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	15	12	theme	biopolymers	2535:2545	arg1	development					2485:2495	development	2485:2495	development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2485:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	1	13	theme	biocompatible	176:188	arg1	materials					190:198	various functional biocompatible materials	157:198	various functional biocompatible materials	157:198	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	15	14	theme	bone	2691:2694	arg1	regeneration					2703:2714	bone tissue regeneration	2691:2714	bone tissue regeneration	2691:2714	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	6	15	theme	mechanical	773:782	arg1	properties					799:808	the mechanical and biological properties	769:808	the mechanical and biological properties of the hydrogels	769:825	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	2	16	theme	polysaccharide-based	299:318	arg1	hydrogel					320:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	In this study, a self-healing and injectable polysaccharide-based hydrogel was prepared for bone tissue engineering.					
36152907	15	17	theme	hydrogels	2518:2526	arg1	biopolymers					2535:2545	dual cross-linked hydrogels basing biopolymers	2500:2545	dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2500:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	8	18	theme	10 mg/mL	1184:1191	arg1	MHGMs					1193:1197	6% (w/v) HAp and 10 mg/mL MHGMs	1167:1197	MHGMs	1193:1197	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	0	19	theme	bone	114:117	arg1	repair					119:124	bone repair	114:124	bone repair	114:124	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	3	20	theme	Schiff-base	501:511	arg1	reaction					513:520	the Schiff-base reaction	497:520	the Schiff-base reaction	497:520	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	15	21	theme	dual	2500:2503	arg1	biopolymers					2535:2545	dual cross-linked hydrogels basing biopolymers	2500:2545	dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2500:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	1	22	theme	rapid	210:214	arg1	progress					216:223	rapid progress	210:223	rapid progress in the field of bone repair	210:251	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	1	23	from	progress	216:223	arg1	field					232:236	the field	228:236	the field of bone repair	228:251	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	8	24	theme	magnetic	1214:1221	arg1	responsiveness					1223:1236	good magnetic responsiveness	1209:1236	good magnetic responsiveness	1209:1236	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	11	25	theme	cell	1809:1812	arg1	proliferation					1814:1826	rapid cell proliferation	1803:1826	rapid cell proliferation	1803:1826	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	13	26	theme	self-healing	2146:2157	arg1	properties					2159:2168	self-healing properties	2146:2168	self-healing properties	2146:2168	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	11	27	theme	drug	1924:1927	arg1	delivery					1929:1936	drug delivery	1924:1936	drug delivery	1924:1936	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	10	28	theme	retardation	1632:1642	arg1	properties					1644:1653	good drug retardation properties	1622:1653	good drug retardation properties	1622:1653	In addition, this composite hydrogel showed good drug retardation properties and antibacterial effects against both S. aureus and E. coli.					
36152907	7	29	theme	composite	992:1000	arg1	hydrogels					1002:1010	the composite hydrogels	988:1010	the composite hydrogels	988:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	9	30	theme	51.9	1437:1440	arg1	%					1441:1441	%	1441:1441	%	1441:1441	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	31	dep	120.8	1496:1500	arg1	to					1493:1494	to	1493:1494	to	1493:1494	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	13	32	theme	Injectable	2116:2125	arg1	hydrogels					2127:2135	Injectable hydrogels	2116:2135	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli	2116:2207	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	13	32	theme	Injectable	2116:2125	arg1	scaffolds					2252:2260	cell scaffolds	2247:2260	cell scaffolds	2247:2260	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	13	32	theme	Injectable	2116:2125	arg1	defects					2271:2277	bone defects	2266:2277	bone defects	2266:2277	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	0	33	theme	dual	73:76	arg1	cross-linking					78:90	dual cross-linking	73:90	dual cross-linking for drug delivery and bone repair	73:124	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	7	34	theme	rheological	962:972	arg1	properties					974:983	The physical, chemical, mechanical and rheological properties	923:983	The physical, chemical, mechanical and rheological properties of the composite hydrogels	923:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	1	35	theme	various	157:163	arg1	materials					190:198	various functional biocompatible materials	157:198	various functional biocompatible materials	157:198	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	8	36	dep	%	1168:1168	arg1	w/v					1171:1173	w/v	1171:1173	w/v	1171:1173	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	8	37	with	hydrogel	1153:1160	arg1	HAp					1176:1178	6% (w/v) HAp and 10 mg/mL MHGMs	1167:1197	HAp	1176:1178	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	8	37	with	hydrogel	1153:1160	arg1	MHGMs					1193:1197	6% (w/v) HAp and 10 mg/mL MHGMs	1167:1197	MHGMs	1193:1197	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	7	38	theme	mechanical	947:956	arg1	properties					974:983	The physical, chemical, mechanical and rheological properties	923:983	The physical, chemical, mechanical and rheological properties of the composite hydrogels	923:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	9	39	from	increase	1518:1525	arg1	120 s					1377:1381	120 s	1377:1381	120 s	1377:1381	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	mass					1455:1458	mass	1455:1458	mass residual after degradation (79.5 to 120.8%)	1455:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	rate					1414:1417	swelling rate	1405:1417	swelling rate (39.4 to 13.6)	1405:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	time					1364:1367	gelation time	1355:1367	gelation time (196 to 120 s)	1355:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	13.6					1428:1431	13.6	1428:1431	13.6	1428:1431	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	39	from	increase	1518:1525	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	1	40	theme	Injectable	127:136	arg1	hydrogels					138:146	Injectable hydrogels	127:146	Injectable hydrogels based on various functional biocompatible materials	127:198	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	12	41	theme	delivery	2106:2113	arg1	treatment					2065:2073	the treatment	2061:2073	the treatment of tissue engineering and drug delivery	2061:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	0	42	theme	injectable	29:38	arg1	hydrogel					51:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	7	43	theme	chemical	937:944	arg1	properties					974:983	The physical, chemical, mechanical and rheological properties	923:983	The physical, chemical, mechanical and rheological properties of the composite hydrogels	923:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	11	44	theme	cell	1776:1779	arg1	%					1796:1796	> 87%	1792:1796	> 87%	1792:1796	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	11	44	theme	cell	1776:1779	arg1	viability					1781:1789	high cell viability	1771:1789	high cell viability (> 87%)	1771:1797	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	7	45	theme	physical	927:934	arg1	properties					974:983	The physical, chemical, mechanical and rheological properties	923:983	The physical, chemical, mechanical and rheological properties of the composite hydrogels	923:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	12	46	theme	tissue	2078:2083	arg1	engineering					2085:2095	tissue engineering	2078:2095	tissue engineering	2078:2095	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	9	47	theme	%	1340:1340	arg1	reduction					1342:1350	a 38.8% reduction	1334:1350	a 38.8% reduction in gelation time (196 to 120 s)	1334:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	12	48	theme	promising	2037:2045	arg1	materials					2047:2055	the promising materials	2033:2055	the promising materials for the treatment of tissue engineering and drug delivery	2033:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	12	48	theme	promising	2037:2045	arg1	hydrogels					1999:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	3	49	theme	oxidized	455:462	arg1	gum					471:473	calcium pre-cross-linked oxidized gellan gum	430:473	calcium pre-cross-linked oxidized gellan gum	430:473	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	14	50	theme	drug	2428:2431	arg1	delivery					2433:2440	targeted drug delivery	2419:2440	targeted drug delivery	2419:2440	Magnetism has also been involved in biomedical applications and played significant roles in targeted drug delivery and anti-cancer therapy.					
36152907	3	51	theme	carboxymethyl	396:408	arg1	chitosan					410:417	carboxymethyl chitosan	396:417	carboxymethyl chitosan (CMCS)	396:424	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	3	51	theme	carboxymethyl	396:408	arg1	OGG					476:478	OGG	476:478	OGG	476:478	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	3	51	theme	carboxymethyl	396:408	arg1	CMCS					420:423	CMCS	420:423	CMCS	420:423	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	2	52	theme	bone	346:349	arg1	engineering					358:368	bone tissue engineering	346:368	bone tissue engineering	346:368	In this study, a self-healing and injectable polysaccharide-based hydrogel was prepared for bone tissue engineering.					
36152907	0	53	theme	biopolymer	40:49	arg1	hydrogel					51:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	15	54	with	biopolymers	2535:2545	arg1	multi-functionalities					2552:2572	multi-functionalities	2552:2572	multi-functionalities	2552:2572	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	15	54	with	biopolymers	2535:2545	arg1	properties					2637:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	4	55	theme	magnetic	534:541	arg1	Meanwhile					523:531	Meanwhile	523:531	Meanwhile	523:531	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	4	55	theme	magnetic	534:541	arg1	MHGMs					580:584	MHGMs	580:584	MHGMs	580:584	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	4	55	theme	magnetic	534:541	arg1	microspheres					566:577	magnetic hydroxyapatite/gelatin microspheres	534:577	magnetic hydroxyapatite/gelatin microspheres (MHGMs)	534:585	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	11	56	theme	CCK-8	1717:1721	arg1	assay					1723:1727	CCK-8 assay	1717:1727	CCK-8 assay	1717:1727	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	6	57	theme	composite	828:836	arg1	hydrogels					838:846	composite hydrogels	828:846	composite hydrogels	828:846	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	9	58	theme	%	1516:1516	arg1	increase					1518:1525	a 143.7% increase	1509:1525	a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa)	1509:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	4	59	theme	emulsion	608:615	arg1	method					631:636	the emulsion cross-linking method	604:636	the emulsion cross-linking method	604:636	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	9	60	from	decrease	1393:1400	arg1	120 s					1377:1381	120 s	1377:1381	120 s	1377:1381	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	mass					1455:1458	mass	1455:1458	mass residual after degradation (79.5 to 120.8%)	1455:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	rate					1414:1417	swelling rate	1405:1417	swelling rate (39.4 to 13.6)	1405:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	time					1364:1367	gelation time	1355:1367	gelation time (196 to 120 s)	1355:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	13.6					1428:1431	13.6	1428:1431	13.6	1428:1431	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	60	from	decrease	1393:1400	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	15	61	link	cross-linked	2505:2516	arg1	biopolymers					2535:2545	dual cross-linked hydrogels basing biopolymers	2500:2545	dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2500:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	5	62	theme	tetracycline	664:675	arg1	drugs					657:661	The antibacterial drugs	639:661	The antibacterial drugs	639:661	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	62	theme	tetracycline	664:675	arg1	hydrochloride					677:689	tetracycline hydrochloride	664:689	tetracycline hydrochloride (TH)	664:694	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	62	theme	tetracycline	664:675	arg1	TH					692:693	TH	692:693	TH	692:693	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	11	63	theme	composite	1741:1749	arg1	hydrogel					1751:1758	composite hydrogel	1741:1758	composite hydrogel	1741:1758	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	1	64	theme	repair	246:251	arg1	field					232:236	the field	228:236	the field of bone repair	228:251	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	14	65	theme	biomedical	2363:2372	arg1	applications					2374:2385	biomedical applications	2363:2385	biomedical applications	2363:2385	Magnetism has also been involved in biomedical applications and played significant roles in targeted drug delivery and anti-cancer therapy.					
36152907	9	66	theme	compressive	1538:1548	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	66	theme	compressive	1538:1548	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	2	67	theme	self-healing	271:282	arg1	hydrogel					320:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	In this study, a self-healing and injectable polysaccharide-based hydrogel was prepared for bone tissue engineering.					
36152907	9	68	theme	65.6	1387:1390	arg1	%					1391:1391	%	1391:1391	%	1391:1391	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	8	69	theme	6	1167:1167	arg1	%					1168:1168	%	1168:1168	%	1168:1168	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	7	70	dep	in	1043:1044	arg1	vitro					1046:1050	vitro	1046:1050	vitro	1046:1050	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	15	71	theme	tissue	2696:2701	arg1	regeneration					2703:2714	bone tissue regeneration	2691:2714	bone tissue regeneration	2691:2714	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	10	72	theme	good	1622:1625	arg1	properties					1644:1653	good drug retardation properties	1622:1653	good drug retardation properties	1622:1653	In addition, this composite hydrogel showed good drug retardation properties and antibacterial effects against both S. aureus and E. coli.					
36152907	1	73	theme	functional	165:174	arg1	materials					190:198	various functional biocompatible materials	157:198	various functional biocompatible materials	157:198	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
36152907	12	74	theme	SIGNIFICANCE	1974:1985	arg1	STATEMENT					1961:1969	STATEMENT	1961:1969	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	9	75	theme	swelling	1405:1412	arg1	rate					1414:1417	swelling rate	1405:1417	swelling rate (39.4 to 13.6)	1405:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	75	theme	swelling	1405:1412	arg1	13.6					1428:1431	13.6	1428:1431	13.6	1428:1431	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	3	76	link	pre-cross-linked	438:453	arg1	gum					471:473	calcium pre-cross-linked oxidized gellan gum	430:473	calcium pre-cross-linked oxidized gellan gum	430:473	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	12	77	theme	Biopolymer	1988:1997	arg1	materials					2047:2055	the promising materials	2033:2055	the promising materials for the treatment of tissue engineering and drug delivery	2033:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	12	77	theme	Biopolymer	1988:1997	arg1	hydrogels					1999:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	2	78	theme	injectable	288:297	arg1	hydrogel					320:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	a self-healing and injectable polysaccharide-based hydrogel	269:327	In this study, a self-healing and injectable polysaccharide-based hydrogel was prepared for bone tissue engineering.					
36152907	15	79	theme	basing	2528:2533	arg1	biopolymers					2535:2545	dual cross-linked hydrogels basing biopolymers	2500:2545	dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2500:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	10	80	theme	antibacterial	1659:1671	arg1	effects					1673:1679	antibacterial effects	1659:1679	antibacterial effects	1659:1679	In addition, this composite hydrogel showed good drug retardation properties and antibacterial effects against both S. aureus and E. coli.					
36152907	9	81	dep	120 s	1377:1381	arg1	to					1374:1375	to	1374:1375	to	1374:1375	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	7	82	theme	antibacterial	1052:1064	arg1	tests					1066:1070	in vitro antibacterial tests	1043:1070	in vitro antibacterial tests	1043:1070	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	15	83	theme	cross-linked	2505:2516	arg1	biopolymers					2535:2545	dual cross-linked hydrogels basing biopolymers	2500:2545	dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties,	2500:2647	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	13	84	theme	external	2192:2199	arg1	stimuli					2201:2207	external stimuli	2192:2207	external stimuli	2192:2207	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	11	85	theme	alternative	1899:1909	arg1	scaffold					1911:1918	an alternative scaffold	1896:1918	an alternative scaffold for drug delivery and bone regeneration	1896:1958	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	11	85	theme	alternative	1899:1909	arg1	hydrogel					1869:1876	this smart hydrogel	1858:1876	this smart hydrogel	1858:1876	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	12	86	theme	STATEMENT	1961:1969	arg1	materials					2047:2055	the promising materials	2033:2055	the promising materials for the treatment of tissue engineering and drug delivery	2033:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	12	86	theme	STATEMENT	1961:1969	arg1	hydrogels					1999:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels	1961:2007	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	15	87	theme	injectable	2583:2592	arg1	properties					2637:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	7	88	theme	in	1043:1044	arg1	tests					1066:1070	in vitro antibacterial tests	1043:1070	in vitro antibacterial tests	1043:1070	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	11	89	theme	rapid	1803:1807	arg1	proliferation					1814:1826	rapid cell proliferation	1803:1826	rapid cell proliferation	1803:1826	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	8	90	theme	good	1209:1212	arg1	responsiveness					1223:1236	good magnetic responsiveness	1209:1236	good magnetic responsiveness	1209:1236	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	11	91	theme	bone	1942:1945	arg1	regeneration					1947:1958	bone regeneration	1942:1958	bone regeneration	1942:1958	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	5	92	theme	silver	700:705	arg1	drugs					657:661	The antibacterial drugs	639:661	The antibacterial drugs	639:661	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	92	theme	silver	700:705	arg1	AgSD					721:724	AgSD	721:724	AgSD	721:724	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	5	92	theme	silver	700:705	arg1	sulfadiazine					707:718	silver sulfadiazine	700:718	silver sulfadiazine (AgSD)	700:725	The antibacterial drugs, tetracycline hydrochloride (TH) and silver sulfadiazine (AgSD), were embedded into the MHGMs.					
36152907	13	93	theme	prolonged	2307:2315	arg1	lifetime					2317:2324	prolonged lifetime	2307:2324	prolonged lifetime	2307:2324	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	15	94	theme	magnetic	2609:2616	arg1	properties					2637:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	7	95	theme	hydrogels	1002:1010	arg1	properties					974:983	The physical, chemical, mechanical and rheological properties	923:983	The physical, chemical, mechanical and rheological properties of the composite hydrogels	923:1010	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	9	96	theme	%	1441:1441	arg1	increase					1443:1450	a 51.9% increase	1435:1450	a 51.9% increase in mass residual after degradation (79.5 to 120.8%)	1435:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	15	97	theme	self-healing	2595:2606	arg1	properties					2637:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	9	98	theme	pure	1289:1292	arg1	hydrogel					1294:1301	the pure hydrogel	1285:1301	the pure hydrogel	1285:1301	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	13	99	with	hydrogels	2127:2135	arg1	responsiveness					2174:2187	responsiveness	2174:2187	responsiveness to external stimuli	2174:2207	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	13	99	with	hydrogels	2127:2135	arg1	properties					2159:2168	self-healing properties	2146:2168	self-healing properties	2146:2168	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	7	100	theme	biocompatibility	1076:1091	arg1	assays					1093:1098	biocompatibility assays	1076:1098	biocompatibility assays	1076:1098	The physical, chemical, mechanical and rheological properties of the composite hydrogels were characterized, as well as in vitro antibacterial tests and biocompatibility assays, respectively.					
36152907	14	101	theme	significant	2398:2408	arg1	roles					2410:2414	significant roles	2398:2414	significant roles	2398:2414	Magnetism has also been involved in biomedical applications and played significant roles in targeted drug delivery and anti-cancer therapy.					
36152907	0	102	theme	drug	96:99	arg1	delivery					101:108	drug delivery	96:108	drug delivery	96:108	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	13	103	theme	cell	2247:2250	arg1	scaffolds					2252:2260	cell scaffolds	2247:2260	cell scaffolds	2247:2260	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	13	103	theme	cell	2247:2250	arg1	hydrogels					2127:2135	Injectable hydrogels	2116:2135	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli	2116:2207	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	9	104	theme	residual	1460:1467	arg1	mass					1455:1458	mass	1455:1458	mass residual after degradation (79.5 to 120.8%)	1455:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	12	105	theme	engineering	2085:2095	arg1	treatment					2065:2073	the treatment	2061:2073	the treatment of tissue engineering and drug delivery	2061:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	9	106	theme	composite	1308:1316	arg1	hydrogel					1318:1325	the composite hydrogel	1304:1325	the composite hydrogel	1304:1325	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	14	107	theme	anti-cancer	2446:2456	arg1	therapy					2458:2464	anti-cancer therapy	2446:2464	anti-cancer therapy	2446:2464	Magnetism has also been involved in biomedical applications and played significant roles in targeted drug delivery and anti-cancer therapy.					
36152907	12	108	theme	drug	2101:2104	arg1	delivery					2106:2113	drug delivery	2101:2113	drug delivery	2101:2113	STATEMENT OF SIGNIFICANCE: Biopolymer hydrogels have been considered as the promising materials for the treatment of tissue engineering and drug delivery.					
36152907	3	109	theme	pre-cross-linked	438:453	arg1	gum					471:473	calcium pre-cross-linked oxidized gellan gum	430:473	calcium pre-cross-linked oxidized gellan gum	430:473	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	0	110	theme	self-healing	2:13	arg1	hydrogel					51:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	0	111	theme	magnetic	16:23	arg1	hydrogel					51:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel	0:58	A self-healing, magnetic and injectable biopolymer hydrogel generated by dual cross-linking for drug delivery and bone repair.					
36152907	9	112	theme	38.8	1336:1339	arg1	%					1340:1340	%	1340:1340	%	1340:1340	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	113	dep	130.6	1566:1570	arg1	to					1563:1564	to	1563:1564	to	1563:1564	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	6	114	theme	compounding	865:875	arg1	HAp					893:895	HAp	893:895	HAp	893:895	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	6	114	theme	compounding	865:875	arg1	hydroxyapatite					877:890	compounding hydroxyapatite	865:890	compounding hydroxyapatite (HAp)	865:896	To improve the mechanical and biological properties of the hydrogels, composite hydrogels were prepared by compounding hydroxyapatite (HAp) and drug-embedded MHGMs.					
36152907	13	115	theme	bone	2266:2269	arg1	hydrogels					2127:2135	Injectable hydrogels	2116:2135	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli	2116:2207	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	13	115	theme	bone	2266:2269	arg1	defects					2271:2277	bone defects	2266:2277	bone defects	2266:2277	Injectable hydrogels with and self-healing properties and responsiveness to external stimuli have been extensively investigated as cell scaffolds and bone defects, due to their diversity and prolonged lifetime.					
36152907	3	116	theme	gellan	464:469	arg1	gum					471:473	calcium pre-cross-linked oxidized gellan gum	430:473	calcium pre-cross-linked oxidized gellan gum	430:473	The hydrogel was made of carboxymethyl chitosan (CMCS) and calcium pre-cross-linked oxidized gellan gum (OGG) cross-linked by the Schiff-base reaction.					
36152907	15	117	theme	anti-bacterial	2622:2635	arg1	properties					2637:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	injectable, self-healing, magnetic and anti-bacterial properties	2583:2646	We speculate that development of dual cross-linked hydrogels basing biopolymers with multi-functionalities, such as injectable, self-healing, magnetic and anti-bacterial properties, would greatly broaden the application for bone tissue regeneration and drug delivery.					
36152907	9	118	theme	gelation	1355:1362	arg1	120 s					1377:1381	120 s	1377:1381	120 s	1377:1381	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	118	theme	gelation	1355:1362	arg1	time					1364:1367	gelation time	1355:1367	gelation time (196 to 120 s)	1355:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	14	119	theme	targeted	2419:2426	arg1	delivery					2433:2440	targeted drug delivery	2419:2440	targeted drug delivery	2419:2440	Magnetism has also been involved in biomedical applications and played significant roles in targeted drug delivery and anti-cancer therapy.					
36152907	4	120	theme	hydroxyapatite/gelatin	543:564	arg1	Meanwhile					523:531	Meanwhile	523:531	Meanwhile	523:531	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	4	120	theme	hydroxyapatite/gelatin	543:564	arg1	MHGMs					580:584	MHGMs	580:584	MHGMs	580:584	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	4	120	theme	hydroxyapatite/gelatin	543:564	arg1	microspheres					566:577	magnetic hydroxyapatite/gelatin microspheres	534:577	magnetic hydroxyapatite/gelatin microspheres (MHGMs)	534:585	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	9	121	from	reduction	1342:1350	arg1	120 s					1377:1381	120 s	1377:1381	120 s	1377:1381	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	mass					1455:1458	mass	1455:1458	mass residual after degradation (79.5 to 120.8%)	1455:1502	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	stress					1550:1555	maximum compressive stress	1530:1555	maximum compressive stress (53.6 to 130.6 KPa)	1530:1575	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	rate					1414:1417	swelling rate	1405:1417	swelling rate (39.4 to 13.6)	1405:1432	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	time					1364:1367	gelation time	1355:1367	gelation time (196 to 120 s)	1355:1382	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	13.6					1428:1431	13.6	1428:1431	13.6	1428:1431	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	121	from	reduction	1342:1350	arg1	KPa					1572:1574	53.6 to 130.6 KPa	1558:1574	53.6 to 130.6 KPa	1558:1574	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	9	122	theme	143.7	1511:1515	arg1	%					1516:1516	%	1516:1516	%	1516:1516	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	4	123	theme	cross-linking	617:629	arg1	method					631:636	the emulsion cross-linking method	604:636	the emulsion cross-linking method	604:636	Meanwhile, magnetic hydroxyapatite/gelatin microspheres (MHGMs) were prepared by the emulsion cross-linking method.					
36152907	9	124	dep	13.6	1428:1431	arg1	to					1425:1426	to	1425:1426	to	1425:1426	Compared with the pure hydrogel, the composite hydrogel showed a 38.8% reduction in gelation time (196 to 120 s), a 65.6% decrease in swelling rate (39.4 to 13.6), a 51.9% increase in mass residual after degradation (79.5 to 120.8%), and a 143.7% increase in maximum compressive stress (53.6 to 130.6 KPa).					
36152907	11	125	theme	high	1771:1774	arg1	%					1796:1796	> 87%	1792:1796	> 87%	1792:1796	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	11	125	theme	high	1771:1774	arg1	viability					1781:1789	high cell viability	1771:1789	high cell viability (> 87%)	1771:1797	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	8	126	theme	composite	1143:1151	arg1	hydrogel					1153:1160	the composite hydrogel	1139:1160	the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs	1139:1197	Our results showed that the composite hydrogel with 6% (w/v) HAp and 10 mg/mL MHGMs exhibited good magnetic responsiveness, self-healing and injectability.					
36152907	11	127	theme	>	1792:1792	arg1	%					1796:1796	> 87%	1792:1796	> 87%	1792:1796	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	11	127	theme	>	1792:1792	arg1	viability					1781:1789	high cell viability	1771:1789	high cell viability (> 87%)	1771:1797	CCK-8 assay showed that composite hydrogel maintained high cell viability (> 87%) and rapid cell proliferation after 3 days, indicating that this smart hydrogel is expected to be an alternative scaffold for drug delivery and bone regeneration.					
36152907	10	128	theme	composite	1596:1604	arg1	hydrogel					1606:1613	this composite hydrogel	1591:1613	this composite hydrogel	1591:1613	In addition, this composite hydrogel showed good drug retardation properties and antibacterial effects against both S. aureus and E. coli.					
36152907	1	129	theme	bone	241:244	arg1	repair					246:251	bone repair	241:251	bone repair	241:251	Injectable hydrogels based on various functional biocompatible materials have made rapid progress in the field of bone repair.					
35963353	0	0	theme	water	97:101	arg1	supply					103:108	enhanced porosity and continuous water supply	64:108	enhanced porosity and continuous water supply	64:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	8	1	theme	microgreen	1174:1183	arg1	growth					1185:1190	microgreen growth	1174:1190	microgreen growth	1174:1190	Finally, the hydrogel composite supported microgreen growth satisfyingly under simulated microgravity despite some morphological changes.					
35963353	7	2	theme	air-filled	989:998	arg1	porosity					1000:1007	Increased air-filled porosity	979:1007	Increased air-filled porosity	979:1007	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	1	3	theme	soilless	188:195	arg1	Hydrogels					163:171	Hydrogels	163:171	Hydrogels	163:171	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	1	3	theme	soilless	188:195	arg1	media					197:201	attractive soilless media	177:201	attractive soilless media for plant cultivation with strong water and nutrient retention	177:264	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	6	4	theme	porous	908:913	arg1	structure					915:923	the porous structure	904:923	the porous structure introduced by GMP	904:941	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	9	5	theme	space	1475:1479	arg1	farming					1481:1487	space farming	1475:1487	space farming	1475:1487	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	0	6	theme	continuous	86:95	arg1	supply					103:108	enhanced porosity and continuous water supply	64:108	enhanced porosity and continuous water supply	64:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	1	7	with	media	197:201	arg1	water					237:241	strong water	230:241	strong water	230:241	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	1	7	with	media	197:201	arg1	retention					256:264	nutrient retention	247:264	nutrient retention	247:264	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	6	8	theme	54 	840:842	arg1	%					843:843	%	843:843	%	843:843	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	9	9	theme	study	1286:1290	arg1	Results					1270:1276	Results	1270:1276	Results of this study	1270:1290	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	5	10	theme	greater	682:688	arg1	volume					701:706	greater total pore volume	682:706	greater total pore volume	682:706	Moreover, the GMP induced greater total pore volume and increased the prevalence of pores >30 μm by 8-fold.					
35963353	2	11	contain	contain	295:301	arg1	hydrogels					285:293	pristine hydrogels	276:293	pristine hydrogels	276:293	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	2	11	contain	contain	295:301	arg2	pores					322:326	ultra-micro pores	310:326	ultra-micro pores	310:326	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	3	12	theme	porous	400:405	arg1	composite					416:424	a porous hydrogel composite	398:424	a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers	398:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	4	13	theme	agarose	507:513	arg1	backbone					515:522	The agarose backbone	503:522	The agarose backbone	503:522	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35963353	5	14	theme	total	690:694	arg1	volume					701:706	greater total pore volume	682:706	greater total pore volume	682:706	Moreover, the GMP induced greater total pore volume and increased the prevalence of pores >30 μm by 8-fold.					
35963353	8	15	theme	simulated	1211:1219	arg1	microgravity					1221:1232	simulated microgravity	1211:1232	simulated microgravity	1211:1232	Finally, the hydrogel composite supported microgreen growth satisfyingly under simulated microgravity despite some morphological changes.					
35963353	7	16	theme	plant	1114:1118	arg1	extraction					1120:1129	plant extraction	1114:1129	plant extraction	1114:1129	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	3	17	theme	particle	479:486	arg1	fillers					494:500	porous growing mix particle (GMP) fillers	460:500	porous growing mix particle (GMP) fillers	460:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	0	18	theme	terrestrial	116:126	arg1	conditions					151:160	terrestrial and microgravitational conditions	116:160	terrestrial and microgravitational conditions	116:160	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	7	19	theme	potential	1093:1101	arg1	levels					1103:1108	favorable water potential levels	1077:1108	favorable water potential levels for plant extraction	1077:1129	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	2	20	theme	ultra-micro	310:320	arg1	pores					322:326	ultra-micro pores	310:326	ultra-micro pores	310:326	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	1	21	theme	plant	207:211	arg1	cultivation					213:223	plant cultivation	207:223	plant cultivation	207:223	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	0	22	theme	hydrogel	8:15	arg1	composite					17:25	Agarose hydrogel composite	0:25	Agarose hydrogel composite	0:25	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	9	23	theme	plant	1407:1411	arg1	growth					1413:1418	plant growth	1407:1418	plant growth	1407:1418	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	2	24	theme	root	361:364	arg1	aeration					371:378	root zone aeration	361:378	root zone aeration	361:378	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	3	25	theme	growing	467:473	arg1	fillers					494:500	porous growing mix particle (GMP) fillers	460:500	porous growing mix particle (GMP) fillers	460:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	0	26	theme	Agarose	0:6	arg1	composite					17:25	Agarose hydrogel composite	0:25	Agarose hydrogel composite	0:25	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	4	27	theme	red	581:583	arg1	microgreens					593:603	red cabbage microgreens	581:603	red cabbage microgreens	581:603	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35963353	9	28	theme	novel	1301:1305	arg1	substrate					1314:1322	a novel growth substrate	1299:1322	a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming	1299:1487	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	9	28	theme	novel	1301:1305	arg1	lightweight					1332:1342	lightweight	1332:1342	lightweight	1332:1342	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	3	29	theme	mix	475:477	arg1	fillers					494:500	porous growing mix particle (GMP) fillers	460:500	porous growing mix particle (GMP) fillers	460:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	3	30	theme	hydrogel	407:414	arg1	composite					416:424	a porous hydrogel composite	398:424	a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers	398:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	7	31	theme	water	1087:1091	arg1	levels					1103:1108	favorable water potential levels	1077:1108	favorable water potential levels for plant extraction	1077:1129	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	8	32	theme	morphological	1247:1259	arg1	changes					1261:1267	some morphological changes	1242:1267	some morphological changes	1242:1267	Finally, the hydrogel composite supported microgreen growth satisfyingly under simulated microgravity despite some morphological changes.					
35963353	1	33	theme	strong	230:235	arg1	water					237:241	strong water	230:241	strong water	230:241	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	0	34	theme	microgravitational	132:149	arg1	conditions					151:160	terrestrial and microgravitational conditions	116:160	terrestrial and microgravitational conditions	116:160	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	2	35	theme	air-filled	337:346	arg1	porosity					348:355	air-filled porosity	337:355	air-filled porosity for root zone aeration	337:378	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	6	36	from	increase	845:852	arg1	yield					868:872	microgreen yield	857:872	microgreen yield	857:872	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	4	37	theme	cabbage	585:591	arg1	microgreens					593:603	red cabbage microgreens	581:603	red cabbage microgreens	581:603	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35963353	6	38	theme	pristine	879:886	arg1	hydrogel					888:895	pristine hydrogel	879:895	pristine hydrogel	879:895	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	3	39	theme	GMP	489:491	arg1	fillers					494:500	porous growing mix particle (GMP) fillers	460:500	porous growing mix particle (GMP) fillers	460:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	0	40	theme	microgreen	36:45	arg1	cultivation					47:57	microgreen cultivation	36:57	microgreen cultivation with enhanced porosity and continuous water supply	36:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	4	41	theme	12-d	559:562	arg1	cycle					571:575	a 12-d growth cycle	557:575	a 12-d growth cycle for red cabbage microgreens	557:603	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35963353	3	42	theme	porous	460:465	arg1	fillers					494:500	porous growing mix particle (GMP) fillers	460:500	porous growing mix particle (GMP) fillers	460:500	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	6	43	from	GMP	820:822	arg1	nutrients					805:813	the nutrients	801:813	the nutrients from GMP	801:822	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	1	44	theme	nutrient	247:254	arg1	retention					256:264	nutrient retention	247:264	nutrient retention	247:264	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	0	45	theme	enhanced	64:71	arg1	supply					103:108	enhanced porosity and continuous water supply	64:108	enhanced porosity and continuous water supply	64:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	5	46	theme	pore	696:699	arg1	volume					701:706	greater total pore volume	682:706	greater total pore volume	682:706	Moreover, the GMP induced greater total pore volume and increased the prevalence of pores >30 μm by 8-fold.					
35963353	8	47	theme	hydrogel	1145:1152	arg1	composite					1154:1162	the hydrogel composite	1141:1162	the hydrogel composite	1141:1162	Finally, the hydrogel composite supported microgreen growth satisfyingly under simulated microgravity despite some morphological changes.					
35963353	7	48	theme	favorable	1077:1085	arg1	levels					1103:1108	favorable water potential levels	1077:1108	favorable water potential levels for plant extraction	1077:1129	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	5	49	theme	pores	740:744	arg1	prevalence					726:735	the prevalence	722:735	the prevalence of pores >30 μm by 8-fold	722:761	Moreover, the GMP induced greater total pore volume and increased the prevalence of pores >30 μm by 8-fold.					
35963353	9	50	theme	multiple	1424:1431	arg1	farming					1463:1469	indoor farming	1456:1469	indoor farming	1456:1469	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	9	50	theme	multiple	1424:1431	arg1	farming					1481:1487	space farming	1475:1487	space farming	1475:1487	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	9	50	theme	multiple	1424:1431	arg1	applications					1433:1444	multiple applications	1424:1444	multiple applications including indoor farming and space farming	1424:1487	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	6	51	theme	microgreen	857:866	arg1	yield					868:872	microgreen yield	857:872	microgreen yield	857:872	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	4	52	theme	growth	564:569	arg1	cycle					571:575	a 12-d growth cycle	557:575	a 12-d growth cycle for red cabbage microgreens	557:603	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35963353	9	53	theme	growth	1307:1312	arg1	substrate					1314:1322	a novel growth substrate	1299:1322	a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming	1299:1487	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	9	53	theme	growth	1307:1312	arg1	lightweight					1332:1342	lightweight	1332:1342	lightweight	1332:1342	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	3	54	theme	agarose	440:446	arg1	network					448:454	an agarose network	437:454	an agarose network	437:454	Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers.					
35963353	6	55	theme	Further	764:770	arg1	investigation					772:784	Further investigation	764:784	Further investigation	764:784	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	7	56	theme	Increased	979:987	arg1	porosity					1000:1007	Increased air-filled porosity	979:1007	Increased air-filled porosity	979:1007	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	7	57	theme	water	1025:1029	arg1	transport					1031:1039	the water transport	1021:1039	the water transport	1021:1039	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	2	58	theme	zone	366:369	arg1	aeration					371:378	root zone aeration	361:378	root zone aeration	361:378	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	9	59	theme	indoor	1456:1461	arg1	farming					1463:1469	indoor farming	1456:1469	indoor farming	1456:1469	Results of this study reveal a novel growth substrate that is lightweight, convenient, and water-efficient, while effectively sustaining plant growth for multiple applications including indoor farming and space farming.					
35963353	6	60	theme	%	843:843	arg1	increase					845:852	a 54 % increase	838:852	a 54 % increase in microgreen yield over pristine hydrogel	838:895	Further investigation suggested that the nutrients from GMP accounted for a 54 % increase in microgreen yield over pristine hydrogel, while the porous structure introduced by GMP improved the yield by another 44 %.					
35963353	7	61	theme	hydrogel	1053:1060	arg1	loss					1045:1048	loss	1045:1048	loss of hydrogel	1045:1060	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	7	61	theme	hydrogel	1053:1060	arg1	transport					1031:1039	the water transport	1021:1039	the water transport	1021:1039	Increased air-filled porosity accelerated the water transport and loss of hydrogel but maintained favorable water potential levels for plant extraction.					
35963353	0	62	theme	porosity	73:80	arg1	supply					103:108	enhanced porosity and continuous water supply	64:108	enhanced porosity and continuous water supply	64:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	2	63	theme	pristine	276:283	arg1	hydrogels					285:293	pristine hydrogels	276:293	pristine hydrogels	276:293	However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration.					
35963353	0	64	with	cultivation	47:57	arg1	supply					103:108	enhanced porosity and continuous water supply	64:108	enhanced porosity and continuous water supply	64:108	Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under terrestrial and microgravitational conditions.					
35963353	1	65	theme	attractive	177:186	arg1	Hydrogels					163:171	Hydrogels	163:171	Hydrogels	163:171	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	1	65	theme	attractive	177:186	arg1	media					197:201	attractive soilless media	177:201	attractive soilless media for plant cultivation with strong water and nutrient retention	177:264	Hydrogels are attractive soilless media for plant cultivation with strong water and nutrient retention.					
35963353	4	66	theme	crew	638:641	arg1	interaction					643:653	crew interaction	638:653	crew interaction	638:653	The agarose backbone allowed the composite to sustain a 12-d growth cycle for red cabbage microgreens without the need for watering or crew interaction.					
35481854	3	0	theme	mechanical	684:693	arg1	properties					695:704	mechanical properties	684:704	mechanical properties	684:704	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	5	1	theme	DSG	1170:1172	arg1	ECM					1159:1161	the connective tissue ECM	1137:1161	the connective tissue ECM of the DSG	1137:1172	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	9	2	theme	regenerative	1850:1861	arg1	medicine					1863:1870	regenerative medicine	1850:1870	regenerative medicine	1850:1870	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	5	3	dep	natural	1000:1006	arg1	compliant					1009:1017	compliant	1009:1017	compliant	1009:1017	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	3	4	theme	tissue	740:745	arg1	ECM					747:749	soft-tissue connective tissue ECM	717:749	soft-tissue connective tissue ECM	717:749	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	3	5	theme	soft-tissue	717:727	arg1	ECM					747:749	soft-tissue connective tissue ECM	717:749	soft-tissue connective tissue ECM	717:749	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	9	6	theme	many	1764:1767	arg1	properties					1795:1804	many structural and functional properties	1764:1804	many structural and functional properties of ECM	1764:1811	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	1	7	theme	native	207:212	arg1	ECM					236:238	ECM	236:238	ECM	236:238	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	1	7	theme	native	207:212	arg1	matrix					228:233	the native extracellular matrix	203:233	the native extracellular matrix (ECM) of the region of interest	203:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	7	8	theme	biocompatible	1407:1419	arg1	scaffolds					1421:1429	biocompatible scaffolds	1407:1429	biocompatible scaffolds	1407:1429	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	7	9	theme	organic	1364:1370	arg1	solvents					1372:1379	organic solvents	1364:1379	organic solvents	1364:1379	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	7	9	theme	organic	1364:1370	arg1	water					1334:1338	water	1334:1338	water	1334:1338	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	8	10	theme	stromal	1686:1692	arg1	phenotype					1699:1707	a stromal cell phenotype	1684:1707	a stromal cell phenotype	1684:1707	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	1	11	theme	matrix	228:233	arg1	properties					189:198	physical, biochemical, and mechanical properties	151:198	physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	151:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	2	12	theme	soft-tissue	547:557	arg1	ECM					559:561	healthy soft-tissue ECM	539:561	healthy soft-tissue ECM	539:561	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	13	theme	ECM-mimicking	316:328	arg1	scaffolds					330:338	Existing ECM-mimicking scaffolds	307:338	Existing ECM-mimicking scaffolds	307:338	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	13	theme	ECM-mimicking	316:328	arg1	hydrogels					381:389	hydrogels	381:389	hydrogels	381:389	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	13	theme	ECM-mimicking	316:328	arg1	sponges					372:378	sponges	372:378	sponges	372:378	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	13	theme	ECM-mimicking	316:328	arg1	mats					366:369	nanofiber (NF) mats	351:369	nanofiber (NF) mats	351:369	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	13	theme	ECM-mimicking	316:328	arg1	composites					408:417	NF-hydrogel composites	396:417	NF-hydrogel composites	396:417	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	8	14	theme	phenotype	1699:1707	arg1	maintenance					1669:1679	maintenance	1669:1679	maintenance of a stromal cell phenotype	1669:1707	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	14	theme	phenotype	1699:1707	arg1	penetration					1586:1596	penetration	1586:1596	penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold	1586:1647	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	14	theme	phenotype	1699:1707	arg1	survival					1655:1662	cell survival	1650:1662	cell survival	1650:1662	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	4	15	theme	Pa	911:912	arg1	modulus					926:932	120 Pa indentation modulus	907:932	120 Pa indentation modulus	907:932	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	3	16	used	used	581:584	arg2	we					578:579	we	578:579	we	578:579	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	5	17	theme	natural	1000:1006	arg1	biomaterials					1019:1030	natural, compliant biomaterials	1000:1030	natural, compliant biomaterials	1000:1030	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	5	17	theme	natural	1000:1006	arg1	alginate					988:995	alginate	988:995	alginate	988:995	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	5	17	theme	natural	1000:1006	arg1	elastin					976:982	elastin	976:982	elastin	976:982	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	4	18	theme	10-30μm	892:898	arg1	pores					900:904	10-30μm pores	892:904	10-30μm pores	892:904	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	6	19	theme	Process	1175:1181	arg1	parameters					1183:1192	Process parameters	1175:1192	Process parameters	1175:1192	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	4	20	theme	s	944:944	arg1	time					962:965	∼200 s relaxation half time	939:965	∼200 s relaxation half time	939:965	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	8	21	theme	3T3	1605:1607	arg1	fibroblasts					1609:1619	NIH 3T3 fibroblasts 250-450µm	1601:1629	NIH 3T3 fibroblasts 250-450µm	1601:1629	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	3	22	theme	3D	619:620	arg1	scaffolds					629:637	3D porous scaffolds	619:637	3D porous scaffolds	619:637	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	1	23	theme	mechanical	178:187	arg1	properties					189:198	physical, biochemical, and mechanical properties	151:198	physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	151:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	4	24	contain	have	867:870	arg2	time					962:965	∼200 s relaxation half time	939:965	∼200 s relaxation half time	939:965	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	24	contain	have	867:870	arg2	pores					900:904	10-30μm pores	892:904	10-30μm pores	892:904	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	24	contain	have	867:870	arg2	modulus					926:932	120 Pa indentation modulus	907:932	120 Pa indentation modulus	907:932	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	24	contain	have	867:870	arg1	matrix					857:862	the decellularized adult salivary gland (DSG) matrix	811:862	the decellularized adult salivary gland (DSG) matrix	811:862	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	24	contain	have	867:870	arg2	backbone					882:889	a fibrous backbone	872:889	a fibrous backbone	872:889	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	25	theme	half	957:960	arg1	time					962:965	∼200 s relaxation half time	939:965	∼200 s relaxation half time	939:965	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	8	26	dep	fibroblasts	1609:1619	arg1	250-450µm					1621:1629	250-450µm	1621:1629	250-450µm	1621:1629	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	2	27	theme	viscoelastic	512:523	arg1	properties					525:534	viscoelastic properties	512:534	viscoelastic properties	512:534	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	4	28	theme	soft	783:786	arg1	model					795:799	our soft tissue model	779:799	our soft tissue model	779:799	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	2	29	theme	NF-hydrogel	396:406	arg1	composites					408:417	NF-hydrogel composites	396:417	NF-hydrogel composites	396:417	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	5	30	theme	cryoelectrospinning	1061:1079	arg1	scaffolds					1081:1089	cryoelectrospinning scaffolds	1061:1089	cryoelectrospinning scaffolds	1061:1089	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	9	31	theme	functional	1784:1793	arg1	properties					1795:1804	many structural and functional properties	1764:1804	many structural and functional properties of ECM	1764:1811	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	1	32	theme	Scaffold-based	99:112	arg1	strategies					127:136	Scaffold-based regenerative strategies	99:136	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	99:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	0	33	theme	Engineering	0:10	arg1	elastin-alginate					28:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	0	33	theme	Engineering	0:10	arg1	matrices					89:96	stromal extracellular matrices	67:96	stromal extracellular matrices	67:96	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	5	34	theme	connective	1141:1150	arg1	ECM					1159:1161	the connective tissue ECM	1137:1161	the connective tissue ECM of the DSG	1137:1172	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	9	35	theme	structural	1769:1778	arg1	properties					1795:1804	many structural and functional properties	1764:1804	many structural and functional properties of ECM	1764:1811	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	5	36	dep	structure	1104:1112	arg1	the					1100:1102	the	1100:1102	the	1100:1102	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	4	37	theme	salivary	760:767	arg1	glands					769:774	salivary glands	760:774	salivary glands	760:774	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	5	38	theme	ECM	1159:1161	arg1	viscoelasticity					1118:1132	viscoelasticity	1118:1132	viscoelasticity	1118:1132	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	5	38	theme	ECM	1159:1161	arg1	structure					1104:1112	structure	1104:1112	structure	1104:1112	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	7	39	theme	fabrication	1498:1508	arg1	process					1510:1516	a green chemistry fabrication process	1480:1516	a green chemistry fabrication process	1480:1516	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	2	40	theme	pore	487:490	arg1	size					492:495	pore size	487:495	pore size	487:495	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	0	41	theme	extracellular	75:87	arg1	elastin-alginate					28:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	0	41	theme	extracellular	75:87	arg1	matrices					89:96	stromal extracellular matrices	67:96	stromal extracellular matrices	67:96	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	4	42	theme	decellularized	815:828	arg1	matrix					857:862	the decellularized adult salivary gland (DSG) matrix	811:862	the decellularized adult salivary gland (DSG) matrix	811:862	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	7	43	theme	green	1482:1486	arg1	process					1510:1516	a green chemistry fabrication process	1480:1516	a green chemistry fabrication process	1480:1516	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	3	44	theme	minimal	644:650	arg1	backbone					660:667	minimal fibrous backbone	644:667	minimal fibrous backbone	644:667	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	4	45	theme	salivary	836:843	arg1	DSG					852:854	DSG	852:854	DSG	852:854	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	45	theme	salivary	836:843	arg1	gland					845:849	adult salivary gland	830:849	the decellularized adult salivary gland (DSG) matrix	811:862	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	5	46	used	used	971:974	arg2	We					968:969	We	968:969	We	968:969	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	8	47	theme	cryoelectrospun	1545:1559	arg1	CESs					1572:1575	CESs	1572:1575	CESs	1572:1575	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	47	theme	cryoelectrospun	1545:1559	arg1	scaffolds					1561:1569	cryoelectrospun scaffolds	1545:1569	cryoelectrospun scaffolds (CESs)	1545:1576	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	48	theme	fibroblasts	1609:1619	arg1	maintenance					1669:1679	maintenance	1669:1679	maintenance of a stromal cell phenotype	1669:1707	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	48	theme	fibroblasts	1609:1619	arg1	penetration					1586:1596	penetration	1586:1596	penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold	1586:1647	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	8	48	theme	fibroblasts	1609:1619	arg1	survival					1655:1662	cell survival	1650:1662	cell survival	1650:1662	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	9	49	theme	potential	1822:1830	arg1	applications					1872:1883	potential for future use in regenerative medicine applications	1822:1883	potential for future use in regenerative medicine applications	1822:1883	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	3	50	theme	pore	670:673	arg1	size					675:678	pore size	670:678	pore size	670:678	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	9	51	theme	future	1836:1841	arg1	use					1843:1845	future use	1836:1845	future use in regenerative medicine	1836:1870	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	6	52	theme	similar	1271:1277	arg1	compliance					1260:1269	compliance	1260:1269	compliance similar to DSG	1260:1284	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	7	53	theme	desirable	1436:1444	arg1	topography					1446:1455	desirable topography	1436:1455	desirable topography	1436:1455	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	2	54	theme	Existing	307:314	arg1	scaffolds					330:338	Existing ECM-mimicking scaffolds	307:338	Existing ECM-mimicking scaffolds	307:338	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	54	theme	Existing	307:314	arg1	hydrogels					381:389	hydrogels	381:389	hydrogels	381:389	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	54	theme	Existing	307:314	arg1	sponges					372:378	sponges	372:378	sponges	372:378	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	54	theme	Existing	307:314	arg1	mats					366:369	nanofiber (NF) mats	351:369	nanofiber (NF) mats	351:369	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	54	theme	Existing	307:314	arg1	composites					408:417	NF-hydrogel composites	396:417	NF-hydrogel composites	396:417	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	8	55	theme	cell	1650:1653	arg1	survival					1655:1662	cell survival	1650:1662	cell survival	1650:1662	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	1	56	theme	cell	281:284	arg1	growth					286:291	cell growth	281:291	cell growth	281:291	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	8	57	theme	NIH	1601:1603	arg1	fibroblasts					1609:1619	NIH 3T3 fibroblasts 250-450µm	1601:1629	NIH 3T3 fibroblasts 250-450µm	1601:1629	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	6	58	theme	desirable	1235:1243	arg1	topography					1245:1254	desirable topography	1235:1254	desirable topography	1235:1254	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	9	59	theme	ECM	1809:1811	arg1	properties					1795:1804	many structural and functional properties	1764:1804	many structural and functional properties of ECM	1764:1811	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	4	60	theme	gland	845:849	arg1	matrix					857:862	the decellularized adult salivary gland (DSG) matrix	811:862	the decellularized adult salivary gland (DSG) matrix	811:862	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	9	61	from	use	1843:1845	arg1	medicine					1863:1870	regenerative medicine	1850:1870	regenerative medicine	1850:1870	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	3	62	theme	connective	729:738	arg1	ECM					747:749	soft-tissue connective tissue ECM	717:749	soft-tissue connective tissue ECM	717:749	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	1	63	theme	extracellular	214:226	arg1	ECM					236:238	ECM	236:238	ECM	236:238	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	1	63	theme	extracellular	214:226	arg1	matrix					228:233	the native extracellular matrix	203:233	the native extracellular matrix (ECM) of the region of interest	203:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	2	64	theme	ECM	559:561	arg1	porosity					498:505	porosity	498:505	porosity	498:505	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	64	theme	ECM	559:561	arg1	topography					475:484	topography	475:484	topography	475:484	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	64	theme	ECM	559:561	arg1	size					492:495	pore size	487:495	pore size	487:495	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	64	theme	ECM	559:561	arg1	composition					462:472	typical composition	454:472	typical composition	454:472	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	2	64	theme	ECM	559:561	arg1	properties					525:534	viscoelastic properties	512:534	viscoelastic properties	512:534	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	6	65	theme	high	1294:1297	arg1	yield					1299:1303	a high yield	1292:1303	a high yield of >100 scaffolds/run	1292:1325	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	8	66	theme	cell	1694:1697	arg1	phenotype					1699:1707	a stromal cell phenotype	1684:1707	a stromal cell phenotype	1684:1707	Here, we demonstrate that cryoelectrospun scaffolds (CESs) support penetration of NIH 3T3 fibroblasts 250-450µm into the scaffold, cell survival, and maintenance of a stromal cell phenotype.					
35481854	2	67	theme	healthy	539:545	arg1	ECM					559:561	healthy soft-tissue ECM	539:561	healthy soft-tissue ECM	539:561	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	1	68	theme	physical	151:158	arg1	properties					189:198	physical, biochemical, and mechanical properties	151:198	physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	151:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	4	69	theme	fibrous	874:880	arg1	backbone					882:889	a fibrous backbone	872:889	a fibrous backbone	872:889	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	3	70	theme	porous	622:627	arg1	scaffolds					629:637	3D porous scaffolds	619:637	3D porous scaffolds	619:637	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	1	71	theme	biochemical	161:171	arg1	properties					189:198	physical, biochemical, and mechanical properties	151:198	physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	151:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	4	72	theme	∼200	939:942	arg1	s					944:944	s	944:944	s	944:944	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	73	theme	relaxation	946:955	arg1	time					962:965	∼200 s relaxation half time	939:965	∼200 s relaxation half time	939:965	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	74	theme	indentation	914:924	arg1	modulus					926:932	120 Pa indentation modulus	907:932	120 Pa indentation modulus	907:932	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	6	75	theme	scaffolds/run	1313:1325	arg1	yield					1299:1303	a high yield	1292:1303	a high yield of >100 scaffolds/run	1292:1325	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	9	76	theme	elastin-alginate	1736:1751	arg1	CESs					1753:1756	elastin-alginate CESs	1736:1756	elastin-alginate CESs	1736:1756	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	0	77	theme	cryoelectrospun	12:26	arg1	elastin-alginate					28:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	0	77	theme	cryoelectrospun	12:26	arg1	matrices					89:96	stromal extracellular matrices	67:96	stromal extracellular matrices	67:96	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	1	78	theme	regenerative	114:125	arg1	strategies					127:136	Scaffold-based regenerative strategies	99:136	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest	99:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	2	79	theme	typical	454:460	arg1	composition					462:472	typical composition	454:472	typical composition	454:472	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	5	80	theme	tissue	1152:1157	arg1	ECM					1159:1161	the connective tissue ECM	1137:1161	the connective tissue ECM of the DSG	1137:1172	We used elastin and alginate as natural, compliant biomaterials and water as the solvent for cryoelectrospinning scaffolds to mimic the structure and viscoelasticity of the connective tissue ECM of the DSG.					
35481854	3	81	theme	fibrous	652:658	arg1	backbone					660:667	minimal fibrous backbone	644:667	minimal fibrous backbone	644:667	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	9	82	contain	have	1817:1820	arg2	applications					1872:1883	potential for future use in regenerative medicine applications	1822:1883	potential for future use in regenerative medicine applications	1822:1883	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	9	82	contain	have	1817:1820	arg1	CESs					1753:1756	elastin-alginate CESs	1736:1756	elastin-alginate CESs	1736:1756	Thus, we demonstrate that elastin-alginate CESs mimic many structural and functional properties of ECM and have potential for future use in regenerative medicine applications.					
35481854	0	83	theme	stromal	67:73	arg1	elastin-alginate					28:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate	0:43	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	0	83	theme	stromal	67:73	arg1	matrices					89:96	stromal extracellular matrices	67:96	stromal extracellular matrices	67:96	Engineering cryoelectrospun elastin-alginate scaffolds to serve as stromal extracellular matrices.					
35481854	7	84	theme	chemistry	1488:1496	arg1	process					1510:1516	a green chemistry fabrication process	1480:1516	a green chemistry fabrication process	1480:1516	Using water as solvent, rather than organic solvents, was critical to generate biocompatible scaffolds with desirable topography; further, it permitted a green chemistry fabrication process.					
35481854	4	85	theme	120	907:909	arg1	Pa					911:912	Pa	911:912	Pa	911:912	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	86	theme	adult	830:834	arg1	DSG					852:854	DSG	852:854	DSG	852:854	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	4	86	theme	adult	830:834	arg1	gland					845:849	adult salivary gland	830:849	the decellularized adult salivary gland (DSG) matrix	811:862	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	2	87	theme	NF	362:363	arg1	mats					366:369	nanofiber (NF) mats	351:369	nanofiber (NF) mats	351:369	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	4	88	theme	tissue	788:793	arg1	model					795:799	our soft tissue model	779:799	our soft tissue model	779:799	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	2	89	theme	nanofiber	351:359	arg1	mats					366:369	nanofiber (NF) mats	351:369	nanofiber (NF) mats	351:369	Existing ECM-mimicking scaffolds, including nanofiber (NF) mats, sponges, hydrogels, and NF-hydrogel composites are unable to simultaneously mimic typical composition, topography, pore size, porosity, and viscoelastic properties of healthy soft-tissue ECM.					
35481854	1	90	theme	region	248:253	arg1	ECM					236:238	ECM	236:238	ECM	236:238	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	1	90	theme	region	248:253	arg1	matrix					228:233	the native extracellular matrix	203:233	the native extracellular matrix (ECM) of the region of interest	203:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
35481854	4	91	used	used	755:758	arg2	We					752:753	We	752:753	We	752:753	We used salivary glands as our soft tissue model and found the decellularized adult salivary gland (DSG) matrix to have a fibrous backbone, 10-30μm pores, 120 Pa indentation modulus, and ∼200 s relaxation half time.					
35481854	3	92	theme	similar	706:712	arg1	backbone					660:667	minimal fibrous backbone	644:667	minimal fibrous backbone	644:667	In this work, we used cryoelectrospinning to fabricate 3D porous scaffolds with minimal fibrous backbone, pore size and mechanical properties similar to soft-tissue connective tissue ECM.					
35481854	6	93	with	scaffolds	1220:1228	arg1	compliance					1260:1269	compliance	1260:1269	compliance similar to DSG	1260:1284	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	6	93	with	scaffolds	1220:1228	arg1	topography					1245:1254	desirable topography	1235:1254	desirable topography	1235:1254	Process parameters were optimized to produce scaffolds with desirable topography and compliance similar to DSG, with a high yield of >100 scaffolds/run.					
35481854	1	94	theme	interest	258:265	arg1	region					248:253	the region	244:253	the region of interest	244:265	Scaffold-based regenerative strategies that emulate physical, biochemical, and mechanical properties of the native extracellular matrix (ECM) of the region of interest can influence cell growth and function.					
36790749	0	0	theme	starch-flaxseed	81:95	arg1	gels					115:118	mung bean starch-flaxseed protein composite gels	71:118	mung bean starch-flaxseed protein composite gels	71:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	4	1	theme	hydrogen	840:847	arg1	bond					849:852	the hydrogen bond	836:852	the hydrogen bond	836:852	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	1	2	from	effect	172:177	arg1	properties					230:239	the textural and microstructural properties	197:239	the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	197:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	2	3	theme	pH-shifting	335:345	arg1	treatment					347:355	different pH-shifting treatment	325:355	different pH-shifting treatment	325:355	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	5	4	theme	extreme	1197:1203	arg1	condition					1210:1218	extreme acid condition	1197:1218	extreme acid condition	1197:1218	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	1	5	theme	bean	249:252	arg1	gels					299:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	0	6	theme	bean	76:79	arg1	gels					115:118	mung bean starch-flaxseed protein composite gels	71:118	mung bean starch-flaxseed protein composite gels	71:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	3	7	theme	looser	666:671	arg1	network					677:683	a looser gel network	664:683	a looser gel network	664:683	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	6	8	theme	starch-protein	1306:1319	arg1	systems					1331:1337	bi-polymeric starch-protein composite systems	1293:1337	bi-polymeric starch-protein composite systems	1293:1337	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	2	9	theme	different	325:333	arg1	treatment					347:355	different pH-shifting treatment	325:355	different pH-shifting treatment	325:355	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	5	10	theme	acid	1205:1208	arg1	condition					1210:1218	extreme acid condition	1197:1218	extreme acid condition	1197:1218	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	1	11	theme	starch	254:259	arg1	bean					249:252	mung bean starch	244:259	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	1	11	theme	starch	254:259	arg1	MBS					262:264	MBS	262:264	MBS	262:264	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	0	12	theme	composite	105:113	arg1	gels					115:118	mung bean starch-flaxseed protein composite gels	71:118	mung bean starch-flaxseed protein composite gels	71:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	3	13	theme	gel	673:675	arg1	network					677:683	a looser gel network	664:683	a looser gel network	664:683	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	5	14	theme	2-treated	1075:1083	arg1	gels					1085:1088	pH 2-treated gels	1072:1088	pH 2-treated gels	1072:1088	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	4	15	theme	hydrophobic	801:811	arg1	groups					813:818	more hydrophobic groups	796:818	more hydrophobic groups	796:818	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	16	theme	2-shifting	515:524	arg1	protein					535:541	The pH 2-shifting modified protein	508:541	The pH 2-shifting modified protein	508:541	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	5	17	theme	pH	970:971	arg1	12-shifting					973:983	pH 12-shifting	970:983	pH 12-shifting	970:983	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	18	theme	MBS	1160:1162	arg1	degradation					1145:1155	the degradation	1141:1155	the degradation of MBS and denaturation of FP caused by extreme acid condition	1141:1218	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	0	19	theme	protein	97:103	arg1	gels					115:118	mung bean starch-flaxseed protein composite gels	71:118	mung bean starch-flaxseed protein composite gels	71:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	5	20	theme	gels	1060:1063	arg1	strength					1048:1055	strength	1048:1055	strength of gels	1048:1063	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	20	theme	gels	1060:1063	arg1	WHC					1022:1024	WHC	1022:1024	WHC	1022:1024	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	20	theme	gels	1060:1063	arg1	capacity					1012:1019	the water-holding capacity	994:1019	the water-holding capacity (WHC)	994:1025	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	20	theme	gels	1060:1063	arg1	modulus					1036:1042	storage modulus	1028:1042	storage modulus	1028:1042	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	4	21	theme	FP	741:742	arg1	change					731:736	conformational change	716:736	conformational change of FP	716:742	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	22	theme	modified	526:533	arg1	protein					535:541	The pH 2-shifting modified protein	508:541	The pH 2-shifting modified protein	508:541	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	6	23	theme	soft	1496:1499	arg1	production					1515:1524	soft gel-type food production	1496:1524	soft gel-type food production	1496:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	2	24	theme	gel	495:497	arg1	network					499:505	loose or compact gel network	478:505	loose or compact gel network	478:505	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	4	25	theme	conformational	716:729	arg1	change					731:736	conformational change	716:736	conformational change of FP	716:742	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	2	26	theme	hydrogen	379:386	arg1	interactions					393:404	hydrogen bond interactions	379:404	hydrogen bond interactions	379:404	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	0	27	theme	gels	115:118	arg1	properties					57:66	textural, thermal and microstructural properties	19:66	textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels	19:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	4	28	theme	groups	813:818	arg1	protein					768:774	protein	768:774	protein	768:774	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	4	28	theme	groups	813:818	arg1	exposure					784:791	the exposure	780:791	the exposure of more hydrophobic groups	780:818	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	6	29	theme	FP	1490:1491	arg1	application					1475:1485	a wide application	1468:1485	a wide application of FP in soft gel-type food production	1468:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	4	30	theme	compact	936:942	arg1	network					948:954	a compact gel network	934:954	a compact gel network	934:954	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	31	with	protein	535:541	arg1	chains					577:582	shorter chains	569:582	shorter chains	569:582	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	5	32	theme	pH	1072:1073	arg1	gels					1085:1088	pH 2-treated gels	1072:1088	pH 2-treated gels	1072:1088	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	33	theme	due	1134:1136	arg1	WHC					1106:1108	lower WHC	1100:1108	lower WHC	1100:1108	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	4	34	theme	network	948:954	arg1	formation					921:929	the formation	917:929	the formation of a compact gel network	917:954	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	35	theme	starch	547:552	arg1	molecules					554:562	starch molecules	547:562	starch molecules with shorter chains	547:582	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	2	36	theme	composite	434:442	arg1	gels					444:447	composite gels	434:447	composite gels	434:447	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	1	37	theme	pH-shifting	182:192	arg1	effect					172:177	the effect	168:177	the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	168:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	38	theme	hydrogen	1397:1404	arg1	bonding					1406:1412	the hydrogen bonding	1393:1412	the hydrogen bonding between the polymers	1393:1433	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	1	39	theme	-flaxseed	266:274	arg1	gels					299:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	40	theme	bi-polymeric	1293:1304	arg1	systems					1331:1337	bi-polymeric starch-protein composite systems	1293:1337	bi-polymeric starch-protein composite systems	1293:1337	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	6	41	from	application	1475:1485	arg1	production					1515:1524	soft gel-type food production	1496:1524	soft gel-type food production	1496:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	6	42	theme	wide	1470:1473	arg1	application					1475:1485	a wide application	1468:1485	a wide application of FP in soft gel-type food production	1468:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	2	43	theme	secondary	410:418	arg1	structures					420:429	secondary structures	410:429	secondary structures	410:429	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	0	44	theme	textural	19:26	arg1	properties					57:66	textural, thermal and microstructural properties	19:66	textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels	19:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	1	45	theme	protein	276:282	arg1	gels					299:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	46	theme	secondary	1356:1364	arg1	structures					1366:1375	the secondary structures	1352:1375	the secondary structures of proteins	1352:1387	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	6	47	theme	gel	1275:1277	arg1	properties					1279:1288	the gel properties	1271:1288	the gel properties of bi-polymeric starch-protein composite systems	1271:1337	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	1	48	theme	textural	201:208	arg1	properties					230:239	the textural and microstructural properties	197:239	the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	197:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	0	49	theme	thermal	29:35	arg1	properties					57:66	textural, thermal and microstructural properties	19:66	textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels	19:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	1	50	theme	FP	285:286	arg1	gels					299:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	51	theme	proteins	1380:1387	arg1	structures					1366:1375	the secondary structures	1352:1375	the secondary structures of proteins	1352:1387	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	6	51	theme	proteins	1380:1387	arg1	bonding					1406:1412	the hydrogen bonding	1393:1412	the hydrogen bonding between the polymers	1393:1433	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	4	52	theme	exposure	784:791	arg1	unfolding					755:763	the unfolding	751:763	the unfolding	751:763	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	2	53	from	changes	368:374	arg1	interactions					393:404	hydrogen bond interactions	379:404	hydrogen bond interactions	379:404	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	2	53	from	changes	368:374	arg1	structures					420:429	secondary structures	410:429	secondary structures	410:429	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	2	53	from	changes	368:374	arg1	gels					444:447	composite gels	434:447	composite gels	434:447	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	2	54	theme	bond	388:391	arg1	interactions					393:404	hydrogen bond interactions	379:404	hydrogen bond interactions	379:404	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	6	55	theme	systems	1331:1337	arg1	properties					1279:1288	the gel properties	1271:1288	the gel properties of bi-polymeric starch-protein composite systems	1271:1337	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	4	56	theme	gel	944:946	arg1	network					948:954	a compact gel network	934:954	a compact gel network	934:954	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	2	57	theme	network	499:505	arg1	formation					465:473	the formation	461:473	the formation of loose or compact gel network	461:505	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	4	58	theme	pH	690:691	arg1	treatment					705:713	pH 12-shifting treatment	690:713	pH 12-shifting treatment	690:713	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	0	59	theme	microstructural	41:55	arg1	properties					57:66	textural, thermal and microstructural properties	19:66	textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels	19:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	1	60	theme	composite	289:297	arg1	gels					299:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	4	61	theme	hydrophobic	858:868	arg1	interactions					870:881	hydrophobic interactions	858:881	hydrophobic interactions between polymers	858:898	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	62	theme	shorter	569:575	arg1	chains					577:582	shorter chains	569:582	shorter chains	569:582	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	1	63	theme	gels	299:302	arg1	properties					230:239	the textural and microstructural properties	197:239	the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	197:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	4	64	theme	protein	768:774	arg1	unfolding					755:763	the unfolding	751:763	the unfolding	751:763	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	3	65	theme	smaller	599:605	arg1	aggregates					622:631	smaller intermolecular aggregates	599:631	smaller intermolecular aggregates	599:631	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	5	66	theme	water-holding	998:1010	arg1	WHC					1022:1024	WHC	1022:1024	WHC	1022:1024	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	66	theme	water-holding	998:1010	arg1	capacity					1012:1019	the water-holding capacity	994:1019	the water-holding capacity (WHC)	994:1025	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	2	67	theme	compact	487:493	arg1	network					499:505	loose or compact gel network	478:505	loose or compact gel network	478:505	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	1	68	theme	microstructural	214:228	arg1	properties					230:239	the textural and microstructural properties	197:239	the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	197:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	69	theme	gel-type	1501:1508	arg1	production					1515:1524	soft gel-type food production	1496:1524	soft gel-type food production	1496:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	3	70	theme	intermolecular	607:620	arg1	aggregates					622:631	smaller intermolecular aggregates	599:631	smaller intermolecular aggregates	599:631	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	4	71	theme	12-shifting	693:703	arg1	treatment					705:713	pH 12-shifting treatment	690:713	pH 12-shifting treatment	690:713	For pH 12-shifting treatment, conformational change of FP caused the unfolding of protein and the exposure of more hydrophobic groups, which enhanced the hydrogen bond and hydrophobic interactions between polymers, contributing to the formation of a compact gel network.					
36790749	6	72	theme	composite	1321:1329	arg1	systems					1331:1337	bi-polymeric starch-protein composite systems	1293:1337	bi-polymeric starch-protein composite systems	1293:1337	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	0	73	theme	mung	71:74	arg1	bean					76:79	mung bean	71:79	mung bean starch-flaxseed protein composite gels	71:118	pH-shifting alters textural, thermal and microstructural properties of mung bean starch-flaxseed protein composite gels.					
36790749	5	74	theme	storage	1028:1034	arg1	modulus					1036:1042	storage modulus	1028:1042	storage modulus	1028:1042	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	75	theme	lower	1100:1104	arg1	WHC					1106:1108	lower WHC	1100:1108	lower WHC	1100:1108	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	1	76	theme	study	143:147	arg1	objective					125:133	The objective	121:133	The objective of this study	121:147	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	6	77	theme	promising	1450:1458	arg1	way					1460:1462	a promising way	1448:1462	a promising way for a wide application of FP in soft gel-type food production	1448:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	5	78	theme	FP	1184:1185	arg1	MBS					1160:1162	MBS	1160:1162	MBS	1160:1162	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	5	78	theme	FP	1184:1185	arg1	denaturation					1168:1179	denaturation	1168:1179	denaturation	1168:1179	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	2	79	theme	loose	478:482	arg1	network					499:505	loose or compact gel network	478:505	loose or compact gel network	478:505	Results showed that different pH-shifting treatment caused the changes in hydrogen bond interactions and secondary structures in composite gels, leading to the formation of loose or compact gel network.					
36790749	3	80	theme	network	677:683	arg1	formation					651:659	the formation	647:659	the formation of a looser gel network	647:683	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	3	81	with	molecules	554:562	arg1	chains					577:582	shorter chains	569:582	shorter chains	569:582	The pH 2-shifting modified protein and starch molecules with shorter chains tended to form smaller intermolecular aggregates, resulting in the formation of a looser gel network.					
36790749	6	82	theme	food	1510:1513	arg1	production					1515:1524	soft gel-type food production	1496:1524	soft gel-type food production	1496:1524	These findings suggest that pH-shifting can alter the gel properties of bi-polymeric starch-protein composite systems by affecting the secondary structures of proteins and the hydrogen bonding between the polymers, and provide a promising way for a wide application of FP in soft gel-type food production.					
36790749	5	83	theme	denaturation	1168:1179	arg1	degradation					1145:1155	the degradation	1141:1155	the degradation of MBS and denaturation of FP caused by extreme acid condition	1141:1218	Furthermore, pH 12-shifting improved the water-holding capacity (WHC), storage modulus and strength of gels, while pH 2-treated gels exhibited lower WHC, hardness and gumminess due to the degradation of MBS and denaturation of FP caused by extreme acid condition.					
36790749	1	84	theme	mung	244:247	arg1	bean					249:252	mung bean starch	244:259	mung bean starch (MBS)-flaxseed protein (FP) composite gels	244:302	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36790749	1	84	theme	mung	244:247	arg1	MBS					262:264	MBS	262:264	MBS	262:264	The objective of this study was to investigate the effect of pH-shifting on the textural and microstructural properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels.					
36280172	7	0	theme	antibacterial	1123:1135	arg1	activities					1137:1146	good antibacterial activities	1118:1146	good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h	1118:1206	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	4	1	dep	DAC	565:567	arg1	the					561:563	the	561:563	the	561:563	The FTIR data showed the covalent cross-linking bond between the DAC and gelatin.					
36280172	8	2	theme	aerogel	1326:1332	arg1	templates					1334:1342	aerogel templates	1326:1342	aerogel templates for oil structuring	1326:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	6	3	theme	lowest	900:905	arg1	diameter					912:919	lowest pore diameter	900:919	lowest pore diameter (10.52 μm)	900:930	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	3	theme	lowest	900:905	arg1	10.52 μm					922:929	10.52 μm	922:929	10.52 μm	922:929	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	4	theme	absorption	986:995	arg1	capacity					997:1004	a high oil absorption capacity	975:1004	a high oil absorption capacity of 11.24 g/g	975:1017	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	3	5	from	chain	444:448	arg1	determination					389:401	The determination	385:401	The determination of aldehyde content in the DAC molecular chain	385:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	7	6	theme	oil	1101:1103	arg1	phase					1105:1109	the oil phase	1097:1109	the oil phase	1097:1109	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	6	7	theme	oil	982:984	arg1	capacity					997:1004	a high oil absorption capacity	975:1004	a high oil absorption capacity of 11.24 g/g	975:1017	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	5	8	theme	mechanical	755:764	arg1	properties					766:775	mechanical properties	755:775	mechanical properties	755:775	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	4	9	theme	cross-linking	534:546	arg1	bond					548:551	the covalent cross-linking bond	521:551	the covalent cross-linking bond between the DAC and gelatin	521:579	The FTIR data showed the covalent cross-linking bond between the DAC and gelatin.					
36280172	7	10	theme	%	1085:1085	arg1	thymol					1087:1092	6 % thymol	1083:1092	6 % thymol	1083:1092	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	6	11	theme	high	977:980	arg1	capacity					997:1004	a high oil absorption capacity	975:1004	a high oil absorption capacity of 11.24 g/g	975:1017	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	0	12	theme	oleogels	107:114	arg1	preparation					116:126	oleogels preparation	107:126	oleogels preparation	107:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	4	13	theme	FTIR	504:507	arg1	data					509:512	The FTIR data	500:512	The FTIR data	500:512	The FTIR data showed the covalent cross-linking bond between the DAC and gelatin.					
36280172	5	14	theme	porous	679:684	arg1	structure					712:720	a porous three-dimensional network structure	677:720	a porous three-dimensional network structure	677:720	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	6	15	theme	%	842:842	arg1	DG-5					849:852	DG-5	849:852	DG-5	849:852	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	15	theme	%	842:842	arg1	DAC					844:846	5 wt% DAC	838:846	5 wt% DAC (DG-5)	838:853	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	2	16	theme	dialdehyde	325:334	arg1	DAC					347:349	DAC	347:349	DAC	347:349	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	2	16	theme	dialdehyde	325:334	arg1	cellulose					336:344	cross-linked dialdehyde cellulose	312:344	cross-linked dialdehyde cellulose (DAC)	312:350	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	3	17	from	content	415:421	arg1	chain					444:448	the DAC molecular chain	426:448	the DAC molecular chain	426:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	5	18	theme	composite	646:654	arg1	DG					665:666	DG	665:666	DG	665:666	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	5	18	theme	composite	646:654	arg1	aerogel					656:662	the composite aerogel	642:662	the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability	642:796	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	2	19	theme	cross-linked	312:323	arg1	DAC					347:349	DAC	347:349	DAC	347:349	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	2	19	theme	cross-linked	312:323	arg1	cellulose					336:344	cross-linked dialdehyde cellulose	312:344	cross-linked dialdehyde cellulose (DAC)	312:350	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	8	20	theme	facile	1230:1235	arg1	strategy					1251:1258	a facile and promising strategy	1228:1258	a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring	1228:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	6	21	with	aerogel	825:831	arg1	DG-5					849:852	DG-5	849:852	DG-5	849:852	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	21	with	aerogel	825:831	arg1	DAC					844:846	5 wt% DAC	838:846	5 wt% DAC (DG-5)	838:853	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	7	22	theme	6 	1083:1084	arg1	%					1085:1085	%	1085:1085	%	1085:1085	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	8	23	theme	oil	1348:1350	arg1	structuring					1352:1362	oil structuring	1348:1362	oil structuring	1348:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	8	24	link	cross-linked	1299:1310	arg1	conjugates					1312:1321	DAC/gelatin cross-linked conjugates	1287:1321	DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring	1287:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	7	25	theme	DG	1060:1061	arg1	oleogels					1063:1070	The DG oleogels	1056:1070	The DG oleogels containing 6 % thymol in the oil phase	1056:1109	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	2	26	link	cross-linked	312:323	arg1	DAC					347:349	DAC	347:349	DAC	347:349	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	2	26	link	cross-linked	312:323	arg1	cellulose					336:344	cross-linked dialdehyde cellulose	312:344	cross-linked dialdehyde cellulose (DAC)	312:350	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	6	27	theme	%	1053:1053	arg1	capacity					1035:1042	oil holding capacity	1023:1042	oil holding capacity of 55.57 %	1023:1053	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	27	theme	%	1053:1053	arg1	capacity					997:1004	a high oil absorption capacity	975:1004	a high oil absorption capacity of 11.24 g/g	975:1017	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	0	28	theme	Schiff	0:5	arg1	base					7:10	Schiff base	0:10	Schiff base	0:10	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	2	29	with	networks	255:262	arg1	structure					282:290	the cellular structure	269:290	the cellular structure	269:290	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	6	30	theme	composite	815:823	arg1	aerogel					825:831	The DAC/gelatin composite aerogel	799:831	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5)	799:853	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	3	31	theme	high	461:464	arg1	degree					466:471	a high degree	459:471	a high degree of oxidation of cellulose	459:497	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	3	32	theme	aldehyde	406:413	arg1	content					415:421	aldehyde content	406:421	aldehyde content in the DAC molecular chain	406:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	8	33	theme	DAC/gelatin	1287:1297	arg1	conjugates					1312:1321	DAC/gelatin cross-linked conjugates	1287:1321	DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring	1287:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	5	34	theme	enhanced	727:734	arg1	stability					744:752	enhanced thermal stability	727:752	enhanced thermal stability	727:752	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	6	35	theme	5 wt	838:841	arg1	DG-5					849:852	DG-5	849:852	DG-5	849:852	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	35	theme	5 wt	838:841	arg1	DAC					844:846	5 wt% DAC	838:846	5 wt% DAC (DG-5)	838:853	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	3	36	theme	cellulose	489:497	arg1	oxidation					476:484	oxidation	476:484	oxidation of cellulose	476:497	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	3	37	theme	content	415:421	arg1	determination					389:401	The determination	385:401	The determination of aldehyde content in the DAC molecular chain	385:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	5	38	theme	thermal	736:742	arg1	stability					744:752	enhanced thermal stability	727:752	enhanced thermal stability	727:752	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	0	39	theme	composite	54:62	arg1	templates					93:101	porous structure templates	76:101	porous structure templates for oleogels preparation	76:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	0	39	theme	composite	54:62	arg1	aerogels					64:71	dialdehyde cellulose/gelatin composite aerogels	25:71	dialdehyde cellulose/gelatin composite aerogels	25:71	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	6	40	theme	holding	1027:1033	arg1	capacity					1035:1042	oil holding capacity	1023:1042	oil holding capacity of 55.57 %	1023:1053	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	5	41	theme	water	782:786	arg1	stability					788:796	water stability	782:796	water stability	782:796	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	3	42	theme	oxidation	476:484	arg1	degree					466:471	a high degree	459:471	a high degree of oxidation of cellulose	459:497	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	0	43	theme	cellulose/gelatin	36:52	arg1	templates					93:101	porous structure templates	76:101	porous structure templates for oleogels preparation	76:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	0	43	theme	cellulose/gelatin	36:52	arg1	aerogels					64:71	dialdehyde cellulose/gelatin composite aerogels	25:71	dialdehyde cellulose/gelatin composite aerogels	25:71	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	6	44	theme	capillary	945:953	arg1	force					955:959	greater capillary force	937:959	greater capillary force	937:959	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	7	45	theme	good	1118:1121	arg1	activities					1137:1146	good antibacterial activities	1118:1146	good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h	1118:1206	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	3	46	from	determination	389:401	arg1	chain					444:448	the DAC molecular chain	426:448	the DAC molecular chain	426:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	0	47	theme	dialdehyde	25:34	arg1	templates					93:101	porous structure templates	76:101	porous structure templates for oleogels preparation	76:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	0	47	theme	dialdehyde	25:34	arg1	aerogels					64:71	dialdehyde cellulose/gelatin composite aerogels	25:71	dialdehyde cellulose/gelatin composite aerogels	25:71	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	6	48	theme	oil	1023:1025	arg1	capacity					1035:1042	oil holding capacity	1023:1042	oil holding capacity of 55.57 %	1023:1053	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	3	49	theme	DAC	430:432	arg1	chain					444:448	the DAC molecular chain	426:448	the DAC molecular chain	426:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	6	50	theme	greater	937:943	arg1	force					955:959	greater capillary force	937:959	greater capillary force	937:959	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	5	51	theme	three-dimensional	686:702	arg1	structure					712:720	a porous three-dimensional network structure	677:720	a porous three-dimensional network structure	677:720	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	6	52	theme	highest	869:875	arg1	porosity					877:884	the highest porosity	865:884	the highest porosity (91.27 %)	865:894	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	52	theme	highest	869:875	arg1	%					893:893	91.27 %	887:893	91.27 %	887:893	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	3	53	theme	molecular	434:442	arg1	chain					444:448	the DAC molecular chain	426:448	the DAC molecular chain	426:448	The determination of aldehyde content in the DAC molecular chain revealed a high degree of oxidation of cellulose.					
36280172	5	54	theme	network	704:710	arg1	structure					712:720	a porous three-dimensional network structure	677:720	a porous three-dimensional network structure	677:720	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	2	55	theme	porous	235:240	arg1	networks					255:262	the porous biopolymeric networks	231:262	the porous biopolymeric networks with the cellular structure	231:290	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	2	56	theme	biopolymeric	242:253	arg1	networks					255:262	the porous biopolymeric networks	231:262	the porous biopolymeric networks with the cellular structure	231:290	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	1	57	theme	biopolymer-based	139:154	arg1	oil					167:169	biopolymer-based structured oil	139:169	biopolymer-based structured oil	139:169	Recently, biopolymer-based structured oil has emerged to substitute saturated and trans-fats.					
36280172	6	58	theme	DAC/gelatin	803:813	arg1	aerogel					825:831	The DAC/gelatin composite aerogel	799:831	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5)	799:853	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	5	59	theme	covalent	586:593	arg1	cross-linking					595:607	The covalent cross-linking	582:607	The covalent cross-linking between DAC and gelatin	582:631	The covalent cross-linking between DAC and gelatin promoted the composite aerogel (DG) to form a porous three-dimensional network structure with enhanced thermal stability, mechanical properties, and water stability.					
36280172	1	60	theme	structured	156:165	arg1	oil					167:169	biopolymer-based structured oil	139:169	biopolymer-based structured oil	139:169	Recently, biopolymer-based structured oil has emerged to substitute saturated and trans-fats.					
36280172	6	61	theme	11.24 g/g	1009:1017	arg1	capacity					1035:1042	oil holding capacity	1023:1042	oil holding capacity of 55.57 %	1023:1053	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	61	theme	11.24 g/g	1009:1017	arg1	capacity					997:1004	a high oil absorption capacity	975:1004	a high oil absorption capacity of 11.24 g/g	975:1017	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	0	62	theme	structure	83:91	arg1	templates					93:101	porous structure templates	76:101	porous structure templates for oleogels preparation	76:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	0	62	theme	structure	83:91	arg1	aerogels					64:71	dialdehyde cellulose/gelatin composite aerogels	25:71	dialdehyde cellulose/gelatin composite aerogels	25:71	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	8	63	theme	promising	1241:1249	arg1	strategy					1251:1258	a facile and promising strategy	1228:1258	a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring	1228:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
36280172	7	64	contain	containing	1072:1081	arg2	thymol					1087:1092	6 % thymol	1083:1092	6 % thymol	1083:1092	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	7	64	contain	containing	1072:1081	arg1	oleogels					1063:1070	The DG oleogels	1056:1070	The DG oleogels containing 6 % thymol in the oil phase	1056:1109	The DG oleogels containing 6 % thymol in the oil phase showed good antibacterial activities against Escherichia coli and Staphylococcus aureus for 24 h.					
36280172	6	65	theme	pore	907:910	arg1	diameter					912:919	lowest pore diameter	900:919	lowest pore diameter (10.52 μm)	900:930	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	6	65	theme	pore	907:910	arg1	10.52 μm					922:929	10.52 μm	922:929	10.52 μm	922:929	The DAC/gelatin composite aerogel with 5 wt% DAC (DG-5) exhibited the highest porosity (91.27 %) and lowest pore diameter (10.52 μm) with greater capillary force, resulting in a high oil absorption capacity of 11.24 g/g and oil holding capacity of 55.57 %.					
36280172	0	66	theme	porous	76:81	arg1	templates					93:101	porous structure templates	76:101	porous structure templates for oleogels preparation	76:126	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	0	66	theme	porous	76:81	arg1	aerogels					64:71	dialdehyde cellulose/gelatin composite aerogels	25:71	dialdehyde cellulose/gelatin composite aerogels	25:71	Schiff base cross-linked dialdehyde cellulose/gelatin composite aerogels as porous structure templates for oleogels preparation.					
36280172	4	67	theme	covalent	525:532	arg1	bond					548:551	the covalent cross-linking bond	521:551	the covalent cross-linking bond between the DAC and gelatin	521:579	The FTIR data showed the covalent cross-linking bond between the DAC and gelatin.					
36280172	2	68	theme	cellular	273:280	arg1	structure					282:290	the cellular structure	269:290	the cellular structure	269:290	Herein, the porous biopolymeric networks with the cellular structure were developed with cross-linked dialdehyde cellulose (DAC) and gelatin to prepare oleogels.					
36280172	8	69	theme	cross-linked	1299:1310	arg1	conjugates					1312:1321	DAC/gelatin cross-linked conjugates	1287:1321	DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring	1287:1362	This work provides a facile and promising strategy for developing oleogels by DAC/gelatin cross-linked conjugates as aerogel templates for oil structuring.					
35487376	0	0	theme	wound	91:95	arg1	healing					97:103	wound healing	91:103	wound healing	91:103	Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing.					
35487376	1	1	from	challenges	175:184	arg1	treatment					115:123	wound treatment	109:123	wound treatment	109:123	In wound treatment, severe bleeding and infection are always primary challenges.					
35487376	3	2	theme	biocomposite	316:327	arg1	BHFs					347:350	BHFs	347:350	BHFs	347:350	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	3	2	theme	biocomposite	316:327	arg1	films					340:344	biocomposite hemostatic films	316:344	biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine	316:394	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	9	3	contain	has	1161:1163	arg1	BHF-6B					1154:1159	the functionalized BHF-6B	1135:1159	the functionalized BHF-6B	1135:1159	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	9	3	contain	has	1161:1163	arg2	potential					1171:1179	great potential	1165:1179	great potential as an absorbable biomaterial for wound treatment	1165:1228	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	5	4	theme	wound	709:713	arg1	healing					715:721	wound healing	709:721	wound healing	709:721	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	6	5	theme	long-term	890:898	arg1	effects					900:906	long-term effects	890:906	long-term effects	890:906	Additionally, BHF-6B showed excellent bacteriostatic activity with long-term effects.					
35487376	5	6	theme	healing	715:721	arg1	time					723:726	a shorter in vivo clotting and wound healing time	678:726	a shorter in vivo clotting and wound healing time	678:726	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	9	7	theme	functionalized	1139:1152	arg1	BHF-6B					1154:1159	the functionalized BHF-6B	1135:1159	the functionalized BHF-6B	1135:1159	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	5	8	from	dressing	752:759	arg1	models					815:820	full-thickness skin defect models	788:820	full-thickness skin defect models	788:820	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	5	8	from	dressing	752:759	arg1	amputation					773:782	rat tail amputation	764:782	rat tail amputation	764:782	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	4	9	theme	hemostatic	501:510	arg1	activities					530:539	the hemostatic and antibacterial activities	497:539	the hemostatic and antibacterial activities	497:539	We have demonstrated that the hemostatic and antibacterial activities were significantly enhanced by calcium/berberine dual-crosslinking system in the film.					
35487376	7	10	theme	cytotoxicity	933:944	arg1	tests					946:950	hemolysis and cytotoxicity tests	919:950	hemolysis and cytotoxicity tests	919:950	Moreover, hemolysis and cytotoxicity tests in vitro illustrated the prominent biocompatibility of the composite films.					
35487376	5	11	theme	full-thickness	788:801	arg1	models					815:820	full-thickness skin defect models	788:820	full-thickness skin defect models	788:820	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	5	12	theme	shorter	680:686	arg1	time					723:726	a shorter in vivo clotting and wound healing time	678:726	a shorter in vivo clotting and wound healing time	678:726	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	6	13	theme	bacteriostatic	861:874	arg1	activity					876:883	excellent bacteriostatic activity	851:883	excellent bacteriostatic activity	851:883	Additionally, BHF-6B showed excellent bacteriostatic activity with long-term effects.					
35487376	2	14	theme	antibacterial	270:282	arg1	capability					284:293	antibacterial capability	270:293	antibacterial capability	270:293	Therefore, it is highly desired to develop novel dressing with both hemostatic and antibacterial capability.					
35487376	9	15	theme	present	1107:1113	arg1	work					1115:1118	the present work	1103:1118	the present work	1103:1118	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	1	16	theme	primary	167:173	arg1	infection					146:154	infection	146:154	infection	146:154	In wound treatment, severe bleeding and infection are always primary challenges.					
35487376	1	16	theme	primary	167:173	arg1	bleeding					133:140	bleeding	133:140	bleeding	133:140	In wound treatment, severe bleeding and infection are always primary challenges.					
35487376	1	16	theme	primary	167:173	arg1	challenges					175:184	primary challenges	167:184	primary challenges	167:184	In wound treatment, severe bleeding and infection are always primary challenges.					
35487376	5	17	theme	skin	803:806	arg1	models					815:820	full-thickness skin defect models	788:820	full-thickness skin defect models	788:820	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	4	18	theme	antibacterial	516:528	arg1	activities					530:539	the hemostatic and antibacterial activities	497:539	the hemostatic and antibacterial activities	497:539	We have demonstrated that the hemostatic and antibacterial activities were significantly enhanced by calcium/berberine dual-crosslinking system in the film.					
35487376	4	19	from	system	608:613	arg1	film					622:625	the film	618:625	the film	618:625	We have demonstrated that the hemostatic and antibacterial activities were significantly enhanced by calcium/berberine dual-crosslinking system in the film.					
35487376	6	20	theme	excellent	851:859	arg1	activity					876:883	excellent bacteriostatic activity	851:883	excellent bacteriostatic activity	851:883	Additionally, BHF-6B showed excellent bacteriostatic activity with long-term effects.					
35487376	7	21	theme	hemolysis	919:927	arg1	tests					946:950	hemolysis and cytotoxicity tests	919:950	hemolysis and cytotoxicity tests	919:950	Moreover, hemolysis and cytotoxicity tests in vitro illustrated the prominent biocompatibility of the composite films.					
35487376	5	22	theme	defect	808:813	arg1	models					815:820	full-thickness skin defect models	788:820	full-thickness skin defect models	788:820	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	3	23	theme	further	442:448	arg1	study					464:468	further biofunctional study	442:468	further biofunctional study	442:468	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	5	24	theme	clotting	696:703	arg1	time					723:726	a shorter in vivo clotting and wound healing time	678:726	a shorter in vivo clotting and wound healing time	678:726	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	5	25	theme	synergistic	640:650	arg1	effects					652:658	the synergistic effects	636:658	the synergistic effects	636:658	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	3	26	theme	biofunctional	450:462	arg1	study					464:468	further biofunctional study	442:468	further biofunctional study	442:468	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	0	27	theme	hemostatic	30:39	arg1	alginate					52:59	biocomposite hemostatic film based alginate	17:59	biocomposite hemostatic film based alginate	17:59	Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing.					
35487376	7	28	theme	composite	1011:1019	arg1	films					1021:1025	the composite films	1007:1025	the composite films	1007:1025	Moreover, hemolysis and cytotoxicity tests in vitro illustrated the prominent biocompatibility of the composite films.					
35487376	7	29	theme	films	1021:1025	arg1	biocompatibility					987:1002	the prominent biocompatibility	973:1002	the prominent biocompatibility of the composite films	973:1025	Moreover, hemolysis and cytotoxicity tests in vitro illustrated the prominent biocompatibility of the composite films.					
35487376	0	30	theme	biocomposite	17:28	arg1	alginate					52:59	biocomposite hemostatic film based alginate	17:59	biocomposite hemostatic film based alginate	17:59	Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing.					
35487376	1	31	theme	wound	109:113	arg1	treatment					115:123	wound treatment	109:123	wound treatment	109:123	In wound treatment, severe bleeding and infection are always primary challenges.					
35487376	9	32	theme	absorbable	1187:1196	arg1	biomaterial					1198:1208	an absorbable biomaterial	1184:1208	an absorbable biomaterial	1184:1208	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	0	33	theme	based	46:50	arg1	alginate					52:59	biocomposite hemostatic film based alginate	17:59	biocomposite hemostatic film based alginate	17:59	Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing.					
35487376	5	34	theme	rat	764:766	arg1	amputation					773:782	rat tail amputation	764:782	rat tail amputation	764:782	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	2	35	theme	novel	230:234	arg1	dressing					236:243	novel dressing	230:243	novel dressing with both hemostatic and antibacterial capability	230:293	Therefore, it is highly desired to develop novel dressing with both hemostatic and antibacterial capability.					
35487376	0	36	theme	film	41:44	arg1	alginate					52:59	biocomposite hemostatic film based alginate	17:59	biocomposite hemostatic film based alginate	17:59	Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing.					
35487376	4	37	theme	calcium/berberine	572:588	arg1	system					608:613	calcium/berberine dual-crosslinking system	572:613	calcium/berberine dual-crosslinking system in the film	572:625	We have demonstrated that the hemostatic and antibacterial activities were significantly enhanced by calcium/berberine dual-crosslinking system in the film.					
35487376	5	38	theme	tail	768:771	arg1	amputation					773:782	rat tail amputation	764:782	rat tail amputation	764:782	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	2	39	with	dressing	236:243	arg1	capability					284:293	antibacterial capability	270:293	antibacterial capability	270:293	Therefore, it is highly desired to develop novel dressing with both hemostatic and antibacterial capability.					
35487376	2	39	with	dressing	236:243	arg1	hemostatic					255:264	hemostatic	255:264	hemostatic	255:264	Therefore, it is highly desired to develop novel dressing with both hemostatic and antibacterial capability.					
35487376	9	40	theme	wound	1214:1218	arg1	treatment					1220:1228	wound treatment	1214:1228	wound treatment	1214:1228	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	5	41	dep	in	688:689	arg1	vivo					691:694	vivo	691:694	vivo	691:694	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	5	42	theme	in	688:689	arg1	clotting					696:703	in vivo clotting	688:703	in vivo clotting	688:703	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	4	43	theme	dual-crosslinking	590:606	arg1	system					608:613	calcium/berberine dual-crosslinking system	572:613	calcium/berberine dual-crosslinking system in the film	572:625	We have demonstrated that the hemostatic and antibacterial activities were significantly enhanced by calcium/berberine dual-crosslinking system in the film.					
35487376	5	44	theme	commercial	741:750	arg1	dressing					752:759	commercial dressing	741:759	commercial dressing in rat tail amputation and full-thickness skin defect models	741:820	Through the synergistic effects, BHF-6B exhibited a shorter in vivo clotting and wound healing time than that of commercial dressing in rat tail amputation and full-thickness skin defect models.					
35487376	7	45	theme	prominent	977:985	arg1	biocompatibility					987:1002	the prominent biocompatibility	973:1002	the prominent biocompatibility of the composite films	973:1025	Moreover, hemolysis and cytotoxicity tests in vitro illustrated the prominent biocompatibility of the composite films.					
35487376	9	46	theme	great	1165:1169	arg1	potential					1171:1179	great potential	1165:1179	great potential as an absorbable biomaterial for wound treatment	1165:1228	Overall, the present work indicated that the functionalized BHF-6B has great potential as an absorbable biomaterial for wound treatment.					
35487376	3	47	theme	hemostatic	329:338	arg1	BHFs					347:350	BHFs	347:350	BHFs	347:350	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	3	47	theme	hemostatic	329:338	arg1	films					340:344	biocomposite hemostatic films	316:344	biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine	316:394	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
35487376	3	48	theme	films	340:344	arg1	series					306:311	a series	304:311	a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine	304:394	Herein, a series of biocomposite hemostatic films (BHFs) based alginate/chitosan/collagen-berberine have been prepared and well characterized for further biofunctional study.					
36737204	0	0	theme	octenyl	78:84	arg1	anhydride					95:103	octenyl succinic anhydride	78:103	octenyl succinic anhydride	78:103	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	1	1	theme	High	181:184	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	1	theme	High	181:184	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	1	theme	High	181:184	arg1	HIPPEs					222:227	HIPPEs	222:227	HIPPEs	222:227	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	6	2	from	conclusion	1102:1111	arg1	composition					1127:1137	the emulsion composition	1114:1137	the emulsion composition (especially at the particle level)	1114:1172	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	6	2	from	conclusion	1102:1111	arg1	vital					1178:1182	vital	1178:1182	vital	1178:1182	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	1	3	theme	internal	186:193	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	3	theme	internal	186:193	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	3	theme	internal	186:193	arg1	HIPPEs					222:227	HIPPEs	222:227	HIPPEs	222:227	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	6	4	theme	topical	1276:1282	arg1	systems					1293:1299	topical delivery systems	1276:1299	topical delivery systems	1276:1299	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	3	5	theme	UV	613:614	arg1	radiation					616:624	UV radiation	613:624	UV radiation	613:624	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	3	6	theme	freeze-thaw	630:640	arg1	treatment					642:650	freeze-thaw treatment	630:650	freeze-thaw treatment	630:650	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	0	7	theme	succinic	86:93	arg1	anhydride					95:103	octenyl succinic anhydride	78:103	octenyl succinic anhydride	78:103	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	6	8	theme	new	1248:1250	arg1	opportunities					1252:1264	new opportunities	1248:1264	new opportunities	1248:1264	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	2	9	theme	network	413:419	arg1	structures					421:430	stable gel-like network structures	397:430	stable gel-like network structures	397:430	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	0	10	theme	complex-stabilized	121:138	arg1	emulsions					170:178	complex-stabilized high internal phase Pickering emulsions	121:178	complex-stabilized high internal phase Pickering emulsions	121:178	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	4	11	theme	antioxidant	803:813	arg1	activity					815:822	the antioxidant activity	799:822	the antioxidant activity of HIPPEs	799:832	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	5	12	theme	resveratrol	1041:1051	arg1	deposition					1053:1062	resveratrol deposition	1041:1062	resveratrol deposition in deep skin compared to bulk oil	1041:1096	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	6	13	from	level	1167:1171	arg1	composition					1127:1137	the emulsion composition	1114:1137	the emulsion composition (especially at the particle level)	1114:1172	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	6	13	from	level	1167:1171	arg1	vital					1178:1182	vital	1178:1182	vital	1178:1182	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	5	14	theme	3-5-fold	1020:1027	arg1	increase					1029:1036	an approximately 3-5-fold increase	1003:1036	an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil	1003:1096	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	1	15	theme	phase	195:199	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	15	theme	phase	195:199	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	15	theme	phase	195:199	arg1	HIPPEs					222:227	HIPPEs	222:227	HIPPEs	222:227	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	4	16	theme	layers	935:940	arg1	existence					902:910	the existence	898:910	the existence of complex interfacial layers	898:940	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	17	theme	resveratrol	864:874	arg1	release					853:859	sustained release	843:859	sustained release of resveratrol	843:874	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	1	18	theme	Pickering	201:209	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	18	theme	Pickering	201:209	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	18	theme	Pickering	201:209	arg1	HIPPEs					222:227	HIPPEs	222:227	HIPPEs	222:227	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	2	19	theme	complex	512:518	arg1	concentrations					520:533	the complex concentrations	508:533	the complex concentrations	508:533	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	5	20	from	increase	1029:1036	arg1	deposition					1053:1062	resveratrol deposition	1041:1062	resveratrol deposition in deep skin compared to bulk oil	1041:1096	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	4	21	theme	High	759:762	arg1	resveratrol					775:785	resveratrol	775:785	resveratrol	775:785	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	21	theme	High	759:762	arg1	amounts					764:770	High amounts	759:770	High amounts of resveratrol	759:785	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	22	theme	HIPPEs	827:832	arg1	activity					815:822	the antioxidant activity	799:822	the antioxidant activity of HIPPEs	799:832	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	23	theme	resveratrol	775:785	arg1	resveratrol					775:785	resveratrol	775:785	resveratrol	775:785	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	23	theme	resveratrol	775:785	arg1	amounts					764:770	High amounts	759:770	High amounts of resveratrol	759:785	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	1	24	theme	topical	318:324	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	24	theme	topical	318:324	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	0	25	theme	internal	145:152	arg1	emulsions					170:178	complex-stabilized high internal phase Pickering emulsions	121:178	complex-stabilized high internal phase Pickering emulsions	121:178	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	4	26	theme	complex	915:921	arg1	layers					935:940	complex interfacial layers	915:940	complex interfacial layers	915:940	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	4	27	theme	sustained	843:851	arg1	release					853:859	sustained release	843:859	sustained release of resveratrol	843:874	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	2	28	theme	dependent	495:503	arg1	size					450:453	droplet size	442:453	droplet size	442:453	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	1	29	theme	delivery	326:333	arg1	emulsions					211:219	High internal phase Pickering emulsions	181:219	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes	181:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	1	29	theme	delivery	326:333	arg1	vehicle					335:341	a topical delivery vehicle	316:341	a topical delivery vehicle for resveratrol	316:357	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	0	30	theme	high	140:143	arg1	emulsions					170:178	complex-stabilized high internal phase Pickering emulsions	121:178	complex-stabilized high internal phase Pickering emulsions	121:178	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	2	31	theme	gel-like	404:411	arg1	structures					421:430	stable gel-like network structures	397:430	stable gel-like network structures	397:430	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	0	32	theme	topical	30:36	arg1	delivery					38:45	topical delivery	30:45	topical delivery	30:45	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	0	33	theme	Pickering	160:168	arg1	emulsions					170:178	complex-stabilized high internal phase Pickering emulsions	121:178	complex-stabilized high internal phase Pickering emulsions	121:178	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	3	34	theme	complexes	732:740	arg1	addition					720:727	the increasing addition	705:727	the increasing addition of complexes and resveratrol	705:756	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	5	35	theme	stratum	973:979	arg1	corneum					981:987	the stratum corneum	969:987	the stratum corneum barrier	969:995	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	2	36	theme	microrheological	459:474	arg1	properties					476:485	microrheological properties	459:485	microrheological properties	459:485	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	6	37	theme	emulsion	1118:1125	arg1	composition					1127:1137	the emulsion composition	1114:1137	the emulsion composition (especially at the particle level)	1114:1172	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	6	37	theme	emulsion	1118:1125	arg1	vital					1178:1182	vital	1178:1182	vital	1178:1182	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	0	38	theme	phase	154:158	arg1	emulsions					170:178	complex-stabilized high internal phase Pickering emulsions	121:178	complex-stabilized high internal phase Pickering emulsions	121:178	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	3	39	theme	increasing	709:718	arg1	addition					720:727	the increasing addition	705:727	the increasing addition of complexes and resveratrol	705:756	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	6	40	theme	particle	1158:1165	arg1	level					1167:1171	the particle level	1154:1171	the particle level	1154:1171	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	4	41	theme	interfacial	923:933	arg1	layers					935:940	complex interfacial layers	915:940	complex interfacial layers	915:940	High amounts of resveratrol facilitated the antioxidant activity of HIPPEs, whereas sustained release of resveratrol was mainly related to the existence of complex interfacial layers.					
36737204	2	42	theme	stable	397:402	arg1	structures					421:430	stable gel-like network structures	397:430	stable gel-like network structures	397:430	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	6	43	dep	level	1167:1171	arg1	especially					1140:1149	especially	1140:1149	especially	1140:1149	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	3	44	theme	resveratrol	657:667	arg1	retention					669:677	resveratrol retention	657:677	resveratrol retention	657:677	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	6	45	theme	HIPPEs	1209:1214	arg1	effectiveness					1192:1204	the effectiveness	1188:1204	the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems	1188:1299	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	5	46	from	deposition	1053:1062	arg1	skin					1072:1075	deep skin	1067:1075	deep skin	1067:1075	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	6	47	theme	delivery	1284:1291	arg1	systems					1293:1299	topical delivery systems	1276:1299	topical delivery systems	1276:1299	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	5	48	theme	bulk	1089:1092	arg1	oil					1094:1096	bulk oil	1089:1096	bulk oil	1089:1096	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	3	49	theme	strong	553:558	arg1	stability					560:568	strong stability	553:568	strong stability	553:568	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	1	50	theme	octenyl	246:252	arg1	anhydride					263:271	octenyl succinic anhydride	246:271	octenyl succinic anhydride starch/chitosan complexes	246:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	5	51	theme	deep	1067:1070	arg1	skin					1072:1075	deep skin	1067:1075	deep skin	1067:1075	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	6	52	from	vital	1178:1182	arg1	conclusion					1102:1111	conclusion	1102:1111	conclusion	1102:1111	In conclusion, the emulsion composition (especially at the particle level) was vital for the effectiveness of HIPPEs as a carrier, which may provide new opportunities to design topical delivery systems.					
36737204	2	53	theme	resveratrol-loaded	364:381	arg1	HIPPEs					383:388	All resveratrol-loaded HIPPEs	360:388	All resveratrol-loaded HIPPEs	360:388	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	1	54	theme	succinic	254:261	arg1	anhydride					263:271	octenyl succinic anhydride	246:271	octenyl succinic anhydride starch/chitosan complexes	246:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	3	55	theme	resveratrol	746:756	arg1	addition					720:727	the increasing addition	705:727	the increasing addition of complexes and resveratrol	705:756	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	2	56	dep	size	450:453	arg1	the					438:440	the	438:440	the	438:440	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	5	57	theme	corneum	981:987	arg1	barrier					989:995	the stratum corneum barrier	969:995	the stratum corneum barrier	969:995	Moreover, HIPPEs overcome the stratum corneum barrier, with an approximately 3-5-fold increase in resveratrol deposition in deep skin compared to bulk oil.					
36737204	2	58	theme	droplet	442:448	arg1	size					450:453	droplet size	442:453	droplet size	442:453	All resveratrol-loaded HIPPEs showed stable gel-like network structures, with the droplet size and microrheological properties largely dependent on the complex concentrations.					
36737204	1	59	theme	anhydride	263:271	arg1	complexes					289:297	octenyl succinic anhydride starch/chitosan complexes	246:297	octenyl succinic anhydride starch/chitosan complexes	246:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
36737204	0	60	theme	resveratrol	50:60	arg1	oxidizability					11:23	oxidizability	11:23	oxidizability	11:23	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	0	60	theme	resveratrol	50:60	arg1	Stability					0:8	Stability	0:8	Stability	0:8	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	0	60	theme	resveratrol	50:60	arg1	delivery					38:45	topical delivery	30:45	topical delivery	30:45	Stability, oxidizability, and topical delivery of resveratrol encapsulated in octenyl succinic anhydride starch/chitosan complex-stabilized high internal phase Pickering emulsions.					
36737204	3	61	theme	high	595:598	arg1	temperature					600:610	high temperature	595:610	high temperature	595:610	HIPPEs exhibited strong stability when subjected to light, high temperature, UV radiation and freeze-thaw treatment, and resveratrol retention was greatly improved with the increasing addition of complexes and resveratrol.					
36737204	1	62	theme	starch/chitosan	273:287	arg1	complexes					289:297	octenyl succinic anhydride starch/chitosan complexes	246:297	octenyl succinic anhydride starch/chitosan complexes	246:297	High internal phase Pickering emulsions (HIPPEs) stabilized with octenyl succinic anhydride starch/chitosan complexes were examined as a topical delivery vehicle for resveratrol.					
35240207	1	0	theme	tissue-engineered	295:311	arg1	graft					318:322	a biomimetic and functional tissue-engineered bone graft	267:322	a biomimetic and functional tissue-engineered bone graft	267:322	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	4	1	theme	bone	1174:1177	arg1	remodeling					1179:1188	bone remodeling	1174:1188	bone remodeling	1174:1188	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	8	2	theme	novel	1896:1900	arg1	candidates					1960:1969	alternative candidates	1948:1969	alternative candidates for bone tissue engineering applications	1948:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	8	2	theme	novel	1896:1900	arg1	scaffold					1918:1925	the novel engineered bone scaffold	1892:1925	the novel engineered bone scaffold	1892:1925	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	3	3	theme	mineralized	804:814	arg1	microparticles					816:829	mineralized microparticles	804:829	mineralized microparticles (labeled oHA-Col/HAP)	804:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	3	3	theme	mineralized	804:814	arg1	oHA-Col/HAP					840:850	labeled oHA-Col/HAP	832:850	labeled oHA-Col/HAP	832:850	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	7	4	theme	genes	1876:1880	arg1	expression					1838:1847	a higher expression	1829:1847	a higher expression of vascularization-related genes	1829:1880	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	6	5	theme	proliferation	1699:1711	arg1	stimulatory					1679:1689	stimulatory	1679:1689	stimulatory	1679:1689	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	1	6	theme	treatment	238:246	arg1	options					248:254	current treatment options	230:254	current treatment options	230:254	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	4	7	theme	separating	1019:1028	arg1	railings					1030:1037	separating railings	1019:1037	separating railings	1019:1037	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	6	8	theme	experimental	1455:1466	arg1	results					1468:1474	The experimental results	1451:1474	The experimental results	1451:1474	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	8	9	theme	engineering	1987:1997	arg1	applications					1999:2010	bone tissue engineering applications	1975:2010	bone tissue engineering applications	1975:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	7	10	theme	higher	1831:1836	arg1	expression					1838:1847	a higher expression	1829:1847	a higher expression of vascularization-related genes	1829:1880	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	2	11	theme	bone	620:623	arg1	remodeling					625:634	bone remodeling	620:634	bone remodeling	620:634	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	4	12	theme	custom-made	985:995	arg1	mandrel					1006:1012	a custom-made rotating mandrel	983:1012	a custom-made rotating mandrel with separating railings	983:1037	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	3	13	theme	engineered	659:668	arg1	scaffold					675:682	an engineered bone scaffold	656:682	an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing	656:927	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	1	14	theme	structural	169:178	arg1	complexity					180:189	the structural complexity	165:189	the structural complexity of natural bone	165:205	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	3	15	theme	bone	916:919	arg1	healing					921:927	bone healing	916:927	bone healing	916:927	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	2	16	theme	viable	524:529	arg1	engineering					493:503	scaffold-guided bone tissue engineering	465:503	scaffold-guided bone tissue engineering	465:503	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	2	16	theme	viable	524:529	arg1	strategy					531:538	a viable strategy	522:538	a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling	522:634	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	5	17	theme	bone	1426:1429	arg1	engineering					1438:1448	bone tissue engineering	1426:1448	bone tissue engineering	1426:1448	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	7	18	theme	regenerative	1791:1802	arg1	capacity					1804:1811	tissue regenerative capacity	1784:1811	tissue regenerative capacity	1784:1811	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	5	19	dep	in	1315:1316	arg1	vivo					1318:1321	vivo	1318:1321	vivo	1318:1321	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	0	20	theme	vascularization	98:112	arg1	properties					114:123	enhanced vascularization properties	89:123	enhanced vascularization properties	89:123	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	1	21	theme	bone	202:205	arg1	limitations					215:225	the limitations	211:225	the limitations of current treatment options	211:254	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	1	21	theme	bone	202:205	arg1	complexity					180:189	the structural complexity	165:189	the structural complexity of natural bone	165:205	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	5	22	theme	physicochemical	1207:1221	arg1	properties					1223:1232	physicochemical properties	1207:1232	physicochemical properties	1207:1232	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	7	23	theme	ideal	1757:1761	arg1	biocompatibility					1763:1778	ideal biocompatibility	1757:1778	ideal biocompatibility	1757:1778	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	4	24	theme	mineralized	1055:1065	arg1	microparticles					1067:1080	HAs-Col/HAP mineralized microparticles	1043:1080	HAs-Col/HAP mineralized microparticles	1043:1080	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	1	25	dep	replacement	356:366	arg1	the					352:354	the	352:354	the	352:354	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	2	26	theme	cell	426:429	arg1	recruitment					431:441	the cell recruitment	422:441	the cell recruitment to the defect region	422:462	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	0	27	theme	tissue	133:138	arg1	engineering					140:150	bone tissue engineering	128:150	bone tissue engineering	128:150	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	4	28	with	mandrel	1006:1012	arg1	railings					1030:1037	separating railings	1019:1037	separating railings	1019:1037	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	2	29	theme	bone	481:484	arg1	engineering					493:503	scaffold-guided bone tissue engineering	465:503	scaffold-guided bone tissue engineering	465:503	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	2	29	theme	bone	481:484	arg1	strategy					531:538	a viable strategy	522:538	a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling	522:634	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	1	30	theme	urgent	336:341	arg1	need					343:346	an urgent need	333:346	an urgent need for the replacement and regeneration of defected bone tissue	333:407	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	0	31	theme	Hyaluronic	0:9	arg1	acid					11:14	Hyaluronic acid	0:14	Hyaluronic acid	0:14	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	5	32	theme	cell	1296:1299	arg1	responses					1301:1309	the cell responses	1292:1309	the cell responses	1292:1309	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	4	33	theme	temporary	1150:1158	arg1	templates					1160:1168	temporary templates	1150:1168	temporary templates for bone remodeling	1150:1188	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	4	33	theme	temporary	1150:1158	arg1	scaffolds					1126:1134	the composite scaffolds	1112:1134	the composite scaffolds that acted as temporary templates for bone remodeling	1112:1188	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	3	34	from	orientation	880:890	arg1	healing					921:927	bone healing	916:927	bone healing	916:927	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	2	35	theme	defect	450:455	arg1	region					457:462	the defect region	446:462	the defect region	446:462	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	7	36	theme	PLGA	1732:1735	arg1	scaffolds					1737:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	3	37	from	osseointegration	896:911	arg1	healing					921:927	bone healing	916:927	bone healing	916:927	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	7	38	theme	oHA-Col/HAP	1720:1730	arg1	scaffolds					1737:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	0	39	theme	aligned	65:71	arg1	nanofibers					73:82	aligned nanofibers	65:82	aligned nanofibers with enhanced vascularization properties	65:123	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	6	40	dep	migration	1610:1618	arg1	the					1606:1608	the	1606:1608	the	1606:1608	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	2	41	theme	recruitment	431:441	arg1	light					413:417	light	413:417	light of the cell recruitment to the defect region	413:462	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	5	42	theme	scaffolds	1368:1376	arg1	responses					1301:1309	the cell responses	1292:1309	the cell responses	1292:1309	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	5	42	theme	scaffolds	1368:1376	arg1	biodegradability					1344:1359	biodegradability	1344:1359	biodegradability	1344:1359	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	5	42	theme	scaffolds	1368:1376	arg1	biocompatibility					1323:1338	biocompatibility	1323:1338	biocompatibility	1323:1338	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	0	43	with	product	53:59	arg1	properties					114:123	enhanced vascularization properties	89:123	enhanced vascularization properties	89:123	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	6	44	theme	osseointegration-related	1639:1662	arg1	cells					1664:1668	osseointegration-related cells	1639:1668	osseointegration-related cells	1639:1668	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	1	45	theme	functional	284:293	arg1	graft					318:322	a biomimetic and functional tissue-engineered bone graft	267:322	a biomimetic and functional tissue-engineered bone graft	267:322	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	4	46	theme	aligned	934:940	arg1	nanofibers					942:951	The aligned nanofibers	930:951	The aligned nanofibers	930:951	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	8	47	theme	bone	1913:1916	arg1	candidates					1960:1969	alternative candidates	1948:1969	alternative candidates for bone tissue engineering applications	1948:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	8	47	theme	bone	1913:1916	arg1	scaffold					1918:1925	the novel engineered bone scaffold	1892:1925	the novel engineered bone scaffold	1892:1925	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	1	48	theme	bone	313:316	arg1	graft					318:322	a biomimetic and functional tissue-engineered bone graft	267:322	a biomimetic and functional tissue-engineered bone graft	267:322	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	3	49	theme	hyaluronic	763:772	arg1	acid					774:777	hyaluronic acid	763:777	hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP)	763:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	2	50	theme	tissue	486:491	arg1	engineering					493:503	scaffold-guided bone tissue engineering	465:503	scaffold-guided bone tissue engineering	465:503	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	2	50	theme	tissue	486:491	arg1	strategy					531:538	a viable strategy	522:538	a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling	522:634	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	7	51	theme	vascularization-related	1852:1874	arg1	genes					1876:1880	vascularization-related genes	1852:1880	vascularization-related genes	1852:1880	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	8	52	theme	alternative	1948:1958	arg1	candidates					1960:1969	alternative candidates	1948:1969	alternative candidates for bone tissue engineering applications	1948:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	8	52	theme	alternative	1948:1958	arg1	scaffold					1918:1925	the novel engineered bone scaffold	1892:1925	the novel engineered bone scaffold	1892:1925	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	1	53	theme	current	230:236	arg1	options					248:254	current treatment options	230:254	current treatment options	230:254	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	2	54	theme	effective	566:574	arg1	osseointegration					576:591	effective osseointegration	566:591	effective osseointegration	566:591	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	3	55	theme	oligosaccharide-collagen	779:802	arg1	acid					774:777	hyaluronic acid	763:777	hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP)	763:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	6	56	theme	cell	1694:1697	arg1	proliferation					1699:1711	cell proliferation	1694:1711	cell proliferation	1694:1711	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	1	57	theme	options	248:254	arg1	limitations					215:225	the limitations	211:225	the limitations of current treatment options	211:254	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	1	57	theme	options	248:254	arg1	complexity					180:189	the structural complexity	165:189	the structural complexity of natural bone	165:205	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	8	58	theme	tissue	1980:1985	arg1	applications					1999:2010	bone tissue engineering applications	1975:2010	bone tissue engineering applications	1975:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	5	59	theme	scaffolds	1262:1270	arg1	morphology					1195:1204	morphology	1195:1204	morphology	1195:1204	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	5	59	theme	scaffolds	1262:1270	arg1	properties					1223:1232	physicochemical properties	1207:1232	physicochemical properties	1207:1232	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	5	59	theme	scaffolds	1262:1270	arg1	strength					1246:1253	tensile strength	1238:1253	tensile strength	1238:1253	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	3	60	theme	labeled	832:838	arg1	microparticles					816:829	mineralized microparticles	804:829	mineralized microparticles (labeled oHA-Col/HAP)	804:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	3	60	theme	labeled	832:838	arg1	oHA-Col/HAP					840:850	labeled oHA-Col/HAP	832:850	labeled oHA-Col/HAP	832:850	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	3	61	theme	cell-specific	866:878	arg1	orientation					880:890	the cell-specific orientation	862:890	the cell-specific orientation	862:890	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	0	62	theme	enhanced	89:96	arg1	properties					114:123	enhanced vascularization properties	89:123	enhanced vascularization properties	89:123	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	7	63	theme	tissue	1784:1789	arg1	capacity					1804:1811	tissue regenerative capacity	1784:1811	tissue regenerative capacity	1784:1811	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	6	64	theme	oHA-Col/HAP	1532:1542	arg1	microparticles					1544:1557	oHA-Col/HAP microparticles	1532:1557	oHA-Col/HAP microparticles	1532:1557	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	3	65	dep	oligosaccharide-collagen	779:802	arg1	microparticles					816:829	mineralized microparticles	804:829	mineralized microparticles (labeled oHA-Col/HAP)	804:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	3	65	dep	oligosaccharide-collagen	779:802	arg1	oHA-Col/HAP					840:850	labeled oHA-Col/HAP	832:850	labeled oHA-Col/HAP	832:850	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	1	66	theme	natural	194:200	arg1	bone					202:205	natural bone	194:205	natural bone	194:205	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	1	67	theme	bone	397:400	arg1	tissue					402:407	defected bone tissue	388:407	defected bone tissue	388:407	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	4	68	theme	rotating	997:1004	arg1	mandrel					1006:1012	a custom-made rotating mandrel	983:1012	a custom-made rotating mandrel with separating railings	983:1037	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	0	69	theme	bone	128:131	arg1	engineering					140:150	bone tissue engineering	128:150	bone tissue engineering	128:150	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	1	70	theme	defected	388:395	arg1	tissue					402:407	defected bone tissue	388:407	defected bone tissue	388:407	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	8	71	theme	bone	1975:1978	arg1	applications					1999:2010	bone tissue engineering applications	1975:2010	bone tissue engineering applications	1975:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	6	72	theme	anisotropic	1498:1508	arg1	scaffolds					1510:1518	such anisotropic scaffolds	1493:1518	such anisotropic scaffolds loaded with oHA-Col/HAP microparticles	1493:1557	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	1	73	theme	tissue	402:407	arg1	regeneration					372:383	regeneration	372:383	regeneration	372:383	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	1	73	theme	tissue	402:407	arg1	replacement					356:366	replacement	356:366	replacement	356:366	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	4	74	theme	HAs-Col/HAP	1043:1053	arg1	microparticles					1067:1080	HAs-Col/HAP mineralized microparticles	1043:1080	HAs-Col/HAP mineralized microparticles	1043:1080	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	1	75	dep	Considering	153:163	arg1	designing					257:265	designing	257:265	designing a biomimetic and functional tissue-engineered bone graft	257:322	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	5	76	theme	tensile	1238:1244	arg1	strength					1246:1253	tensile strength	1238:1253	tensile strength	1238:1253	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	2	77	theme	scaffold-guided	465:479	arg1	engineering					493:503	scaffold-guided bone tissue engineering	465:503	scaffold-guided bone tissue engineering	465:503	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	2	77	theme	scaffold-guided	465:479	arg1	strategy					531:538	a viable strategy	522:538	a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling	522:634	In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling.					
35240207	3	78	theme	poly	701:704	arg1	nanofibers					734:743	aligned poly(lactic-co-glycolide) (PLGA) nanofibers	693:743	aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP)	693:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	5	79	theme	tissue	1431:1436	arg1	engineering					1438:1448	bone tissue engineering	1426:1448	bone tissue engineering	1426:1448	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	0	80	theme	mineralized	41:51	arg1	product					53:59	mineralized product	41:59	mineralized product	41:59	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	6	81	theme	conducive	1593:1601	arg1	arrangement					1581:1591	cell orderly arrangement	1568:1591	cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells	1568:1668	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	5	82	theme	in	1315:1316	arg1	biocompatibility					1323:1338	biocompatibility	1323:1338	biocompatibility	1323:1338	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	3	83	theme	bone	670:673	arg1	scaffold					675:682	an engineered bone scaffold	656:682	an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing	656:927	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	1	84	theme	biomimetic	269:278	arg1	graft					318:322	a biomimetic and functional tissue-engineered bone graft	267:322	a biomimetic and functional tissue-engineered bone graft	267:322	Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue.					
35240207	6	85	theme	such	1493:1496	arg1	scaffolds					1510:1518	such anisotropic scaffolds	1493:1518	such anisotropic scaffolds loaded with oHA-Col/HAP microparticles	1493:1557	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	6	86	theme	orderly	1573:1579	arg1	arrangement					1581:1591	cell orderly arrangement	1568:1591	cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells	1568:1668	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	7	87	theme	@	1731:1731	arg1	scaffolds					1737:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds	1714:1745	Those oHA-Col/HAP@PLGA scaffolds exhibited ideal biocompatibility and tissue regenerative capacity in vivo through a higher expression of vascularization-related genes.					
35240207	4	88	theme	composite	1116:1124	arg1	templates					1160:1168	temporary templates	1150:1168	temporary templates for bone remodeling	1150:1188	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	4	88	theme	composite	1116:1124	arg1	scaffolds					1126:1134	the composite scaffolds	1112:1134	the composite scaffolds that acted as temporary templates for bone remodeling	1112:1188	The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling.					
35240207	5	89	dep	morphology	1195:1204	arg1	The					1191:1193	The	1191:1193	The	1191:1193	The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegradability of the scaffolds were also studied to evaluate the potential for bone tissue engineering.					
35240207	3	90	theme	aligned	693:699	arg1	nanofibers					734:743	aligned poly(lactic-co-glycolide) (PLGA) nanofibers	693:743	aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP)	693:851	Herein, we provide an engineered bone scaffold based on aligned poly(lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing.					
35240207	0	91	with	nanofibers	73:82	arg1	properties					114:123	enhanced vascularization properties	89:123	enhanced vascularization properties	89:123	Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering.					
35240207	8	92	theme	engineered	1902:1911	arg1	candidates					1960:1969	alternative candidates	1948:1969	alternative candidates for bone tissue engineering applications	1948:2010	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	8	92	theme	engineered	1902:1911	arg1	scaffold					1918:1925	the novel engineered bone scaffold	1892:1925	the novel engineered bone scaffold	1892:1925	Overall, the novel engineered bone scaffold promises to serve as alternative candidates for bone tissue engineering applications.					
35240207	6	93	theme	cell	1568:1571	arg1	arrangement					1581:1591	cell orderly arrangement	1568:1591	cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells	1568:1668	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	6	94	theme	cells	1664:1668	arg1	recruitment					1624:1634	recruitment	1624:1634	recruitment	1624:1634	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
35240207	6	94	theme	cells	1664:1668	arg1	migration					1610:1618	migration	1610:1618	migration	1610:1618	The experimental results illustrated that such anisotropic scaffolds loaded with oHA-Col/HAP microparticles mediated cell orderly arrangement conducive to the migration and recruitment of osseointegration-related cells and were stimulatory of cell proliferation.					
36012758	1	0	theme	packaging	158:166	arg1	properties					177:186	packaging material properties	158:186	packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	158:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	0	1	from	Properties	11:20	arg1	Wax-Cellulose					47:59	Wax-Cellulose	47:59	Wax-Cellulose	47:59	Mechanical Properties and Diffusion Studies in Wax-Cellulose Nanocomposite Packaging Material.					
36012758	1	2	theme	material	168:175	arg1	properties					177:186	packaging material properties	158:186	packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	158:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	6	3	theme	Transport	1060:1068	arg1	coefficient					1120:1130	diffusion volume and diffusion coefficient	1089:1130	coefficient	1120:1130	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	3	theme	Transport	1060:1068	arg1	properties					1070:1079	Transport properties	1060:1079	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water	1060:1161	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	3	theme	Transport	1060:1068	arg1	volume					1099:1104	diffusion volume and diffusion coefficient	1089:1130	volume	1099:1104	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	4	theme	water	1157:1161	arg1	coefficient					1120:1130	diffusion volume and diffusion coefficient	1089:1130	coefficient	1120:1130	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	4	theme	water	1157:1161	arg1	volume					1099:1104	diffusion volume and diffusion coefficient	1089:1130	volume	1099:1104	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	4	5	theme	glassy	849:854	arg1	state					856:860	glassy state	849:860	glassy state	849:860	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	2	6	theme	low	366:368	arg1	cost					370:373	low cost	366:373	low cost	366:373	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	7	7	theme	interaction	1337:1347	arg1	energies					1349:1356	the diffusion volume and interaction energies	1312:1356	energies	1349:1356	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	5	8	theme	poor	1033:1036	arg1	strength					1049:1056	poor mechanical strength	1033:1056	poor mechanical strength	1033:1056	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	4	9	from	information	830:840	arg1	state					856:860	glassy state	849:860	glassy state	849:860	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	4	9	from	information	830:840	arg1	state					874:878	rubbery state	866:878	rubbery state	866:878	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	4	10	theme	critical	821:828	arg1	information					830:840	critical information	821:840	critical information on the glassy state and rubbery state of this biopolymer	821:897	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	4	11	theme	glass	765:769	arg1	transition					771:780	the glass transition	761:780	the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer	761:897	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	5	12	theme	glass	904:908	arg1	temperature					921:931	The glass transition temperature	900:931	The glass transition temperature of this composite changes	900:957	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	3	13	theme	polymer	568:574	arg1	materials					576:584	the conventional synthetic polymer materials	541:584	the conventional synthetic polymer materials	541:584	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	4	14	theme	cellulose-wax	710:722	arg1	composite					724:732	the proposed ecofriendly cellulose-wax composite	685:732	the proposed ecofriendly cellulose-wax composite	685:732	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	1	15	theme	properties	177:186	arg1	estimation					144:153	the estimation	140:153	the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	140:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	3	16	dep	wax	421:423	arg1	nonacosane-5,10-diol					447:466	nonacosane-5,10-diol	447:466	nonacosane-5,10-diol	447:466	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	16	dep	wax	421:423	arg1	nonacosane-10-ol					426:441	nonacosane-10-ol	426:441	nonacosane-10-ol	426:441	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	4	17	dep	state	856:860	arg1	the					845:847	the	845:847	the	845:847	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	6	18	theme	nitrogen	1143:1150	arg1	coefficient					1120:1130	diffusion volume and diffusion coefficient	1089:1130	coefficient	1120:1130	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	18	theme	nitrogen	1143:1150	arg1	volume					1099:1104	diffusion volume and diffusion coefficient	1089:1130	volume	1099:1104	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	0	19	from	Studies	36:42	arg1	Wax-Cellulose					47:59	Wax-Cellulose	47:59	Wax-Cellulose	47:59	Mechanical Properties and Diffusion Studies in Wax-Cellulose Nanocomposite Packaging Material.					
36012758	7	20	theme	constituents	1367:1378	arg1	volume					1326:1331	the diffusion volume and interaction energies	1312:1356	volume	1326:1331	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	7	20	theme	constituents	1367:1378	arg1	energies					1349:1356	the diffusion volume and interaction energies	1312:1356	energies	1349:1356	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	1	21	theme	cellulose-wax	191:203	arg1	nanocomposite					205:217	cellulose-wax nanocomposite	191:217	cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	191:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	0	22	theme	Mechanical	0:9	arg1	Properties					11:20	Mechanical Properties	0:20	Mechanical Properties	0:20	Mechanical Properties and Diffusion Studies in Wax-Cellulose Nanocomposite Packaging Material.					
36012758	1	23	theme	nanocomposite	205:217	arg1	properties					177:186	packaging material properties	158:186	packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	158:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	0	24	theme	Diffusion	26:34	arg1	Studies					36:42	Diffusion Studies	26:42	Diffusion Studies in Wax-Cellulose	26:59	Mechanical Properties and Diffusion Studies in Wax-Cellulose Nanocomposite Packaging Material.					
36012758	4	25	theme	rubbery	866:872	arg1	state					874:878	rubbery state	866:878	rubbery state	866:878	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	7	26	with	constituents	1367:1378	arg1	cellulose					1397:1405	cellulose	1397:1405	cellulose	1397:1405	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	7	26	with	constituents	1367:1378	arg1	wax					1389:1391	wax	1389:1391	wax	1389:1391	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	6	27	theme	diffusion	1110:1118	arg1	coefficient					1120:1130	diffusion volume and diffusion coefficient	1089:1130	coefficient	1120:1130	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	4	28	theme	thermal	664:670	arg1	stability					672:680	the thermal stability	660:680	the thermal stability of the proposed ecofriendly cellulose-wax composite	660:732	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	3	29	theme	small	391:395	arg1	amount					397:402	small amount	391:402	small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	391:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	29	theme	small	391:395	arg1	wax					421:423	plant-derived wax	407:423	plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	407:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	5	30	theme	mechanical	1038:1047	arg1	strength					1049:1056	poor mechanical strength	1033:1056	poor mechanical strength	1033:1056	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	4	31	dep	estimation	623:632	arg1	addition					607:614	addition	607:614	addition	607:614	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	2	32	theme	importance	315:324	arg1	lot					308:310	lot	308:310	lot of importance	308:324	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	2	32	theme	importance	315:324	arg1	importance					315:324	importance	315:324	importance	315:324	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	1	33	theme	molecular	225:233	arg1	MDS					256:258	MDS	256:258	MDS	256:258	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	1	33	theme	molecular	225:233	arg1	simulation					244:253	molecular dynamics simulation	225:253	molecular dynamics simulation (MDS)	225:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	3	34	theme	higher	476:481	arg1	strength					494:501	higher mechanical strength	476:501	higher mechanical strength	476:501	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	35	link	plant-derived	407:419	arg1	wax					421:423	plant-derived wax	407:423	plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	407:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	4	36	theme	ecofriendly	698:708	arg1	composite					724:732	the proposed ecofriendly cellulose-wax composite	685:732	the proposed ecofriendly cellulose-wax composite	685:732	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	1	37	theme	dynamics	235:242	arg1	MDS					256:258	MDS	256:258	MDS	256:258	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	1	37	theme	dynamics	235:242	arg1	simulation					244:253	molecular dynamics simulation	225:253	molecular dynamics simulation (MDS)	225:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	4	38	theme	proposed	689:696	arg1	composite					724:732	the proposed ecofriendly cellulose-wax composite	685:732	the proposed ecofriendly cellulose-wax composite	685:732	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	7	39	theme	diffusion	1218:1226	arg1	coefficients					1228:1239	The diffusion coefficients	1214:1239	The diffusion coefficients of these species within the cellulose-wax composite	1214:1291	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	3	40	theme	mechanical	483:492	arg1	strength					494:501	higher mechanical strength	476:501	higher mechanical strength	476:501	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	41	theme	plant-derived	407:419	arg1	wax					421:423	plant-derived wax	407:423	plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	407:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	5	42	theme	changes	951:957	arg1	temperature					921:931	The glass transition temperature	900:931	The glass transition temperature of this composite changes	900:957	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	4	43	theme	biopolymer	888:897	arg1	state					856:860	glassy state	849:860	glassy state	849:860	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	4	43	theme	biopolymer	888:897	arg1	state					874:878	rubbery state	866:878	rubbery state	866:878	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	3	44	theme	elasticity	518:527	arg1	modulus					507:513	modulus	507:513	modulus	507:513	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	44	theme	elasticity	518:527	arg1	strength					494:501	higher mechanical strength	476:501	higher mechanical strength	476:501	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	45	theme	wax	421:423	arg1	amount					397:402	small amount	391:402	small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	391:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	45	theme	wax	421:423	arg1	wax					421:423	plant-derived wax	407:423	plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	407:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	6	46	theme	oxygen	1135:1140	arg1	coefficient					1120:1130	diffusion volume and diffusion coefficient	1089:1130	coefficient	1120:1130	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	6	46	theme	oxygen	1135:1140	arg1	volume					1099:1104	diffusion volume and diffusion coefficient	1089:1130	volume	1099:1104	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	7	47	theme	diffusion	1316:1324	arg1	volume					1326:1331	the diffusion volume and interaction energies	1312:1356	volume	1326:1331	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	3	48	with	Cellulose	376:384	arg1	amount					397:402	small amount	391:402	small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	391:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	3	48	with	Cellulose	376:384	arg1	wax					421:423	plant-derived wax	407:423	plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol)	407:467	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	7	49	theme	cellulose-wax	1269:1281	arg1	composite					1283:1291	the cellulose-wax composite	1265:1291	the cellulose-wax composite	1265:1291	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	1	50	theme	related	129:135	arg1	study					123:127	the study	119:127	the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS)	119:259	This article focuses on the study related to the estimation of packaging material properties of cellulose-wax nanocomposite using molecular dynamics simulation (MDS).					
36012758	6	51	theme	diffusion	1089:1097	arg1	volume					1099:1104	diffusion volume and diffusion coefficient	1089:1130	volume	1099:1104	Transport properties such as diffusion volume and diffusion coefficient of oxygen, nitrogen, and water are estimated using the results obtained from MDS.					
36012758	4	52	theme	composite	724:732	arg1	stability					672:680	the thermal stability	660:680	the thermal stability of the proposed ecofriendly cellulose-wax composite	660:732	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	2	53	theme	material	342:349	arg1	properties					351:360	its good material properties	333:360	its good material properties	333:360	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	5	54	theme	composite	941:949	arg1	changes					951:957	this composite changes	936:957	this composite changes	936:957	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	4	55	theme	mechanical	637:646	arg1	properties					648:657	mechanical properties	637:657	mechanical properties	637:657	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	5	56	theme	pure	993:996	arg1	cellulose					998:1006	pure cellulose	993:1006	pure cellulose (which also suffers from poor mechanical strength)	993:1057	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	2	57	theme	packaging	278:286	arg1	material					288:295	Cellulose based packaging material	262:295	Cellulose based packaging material	262:295	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	2	58	theme	good	337:340	arg1	properties					351:360	its good material properties	333:360	its good material properties	333:360	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	4	59	theme	transition	771:780	arg1	temperature					782:792	the glass transition temperature	761:792	the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer	761:897	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
36012758	5	60	theme	transition	910:919	arg1	temperature					921:931	The glass transition temperature	900:931	The glass transition temperature of this composite changes	900:957	The glass transition temperature of this composite changes significantly compared to that of pure cellulose (which also suffers from poor mechanical strength).					
36012758	2	61	theme	based	272:276	arg1	material					288:295	Cellulose based packaging material	262:295	Cellulose based packaging material	262:295	Cellulose based packaging material is gaining lot of importance due to its good material properties and low cost.					
36012758	3	62	theme	conventional	545:556	arg1	materials					576:584	the conventional synthetic polymer materials	541:584	the conventional synthetic polymer materials	541:584	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	0	63	theme	Packaging	75:83	arg1	Material					85:92	Packaging Material	75:92	Packaging Material	75:92	Mechanical Properties and Diffusion Studies in Wax-Cellulose Nanocomposite Packaging Material.					
36012758	7	64	theme	species	1250:1256	arg1	coefficients					1228:1239	The diffusion coefficients	1214:1239	The diffusion coefficients of these species within the cellulose-wax composite	1214:1291	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	7	65	dep	wax	1389:1391	arg1	the					1385:1387	the	1385:1387	the	1385:1387	The diffusion coefficients of these species within the cellulose-wax composite are analyzed using the diffusion volume and interaction energies of these constituents with the wax and cellulose.					
36012758	3	66	theme	synthetic	558:566	arg1	materials					576:584	the conventional synthetic polymer materials	541:584	the conventional synthetic polymer materials	541:584	Cellulose with small amount of plant-derived wax (nonacosane-10-ol and nonacosane-5,10-diol) offers higher mechanical strength and modulus of elasticity compared to the conventional synthetic polymer materials.					
36012758	4	67	theme	properties	648:657	arg1	estimation					623:632	the estimation	619:632	the estimation of mechanical properties	619:657	In this article, in addition to the estimation of mechanical properties, the thermal stability of the proposed ecofriendly cellulose-wax composite is evaluated by estimating the glass transition temperature which essentially provides critical information on the glassy state and rubbery state of this biopolymer.					
35398061	7	0	theme	MoS2QDs/DEChN	1178:1190	arg1	film					1202:1205	The MoS2QDs/DEChN assembled film	1174:1205	The MoS2QDs/DEChN assembled film	1174:1205	The MoS2QDs/DEChN assembled film could be applied to preserve meat by delaying spoilage.					
35398061	7	1	theme	assembled	1192:1200	arg1	film					1202:1205	The MoS2QDs/DEChN assembled film	1174:1205	The MoS2QDs/DEChN assembled film	1174:1205	The MoS2QDs/DEChN assembled film could be applied to preserve meat by delaying spoilage.					
35398061	1	2	theme	inherent	182:189	arg1	amino					230:234	amino	230:234	amino	230:234	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	2	theme	inherent	182:189	arg1	biocompatibility					191:206	its inherent biocompatibility	178:206	its inherent biocompatibility	178:206	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	2	theme	inherent	182:189	arg1	activity					220:227	biological activity	209:227	biological activity	209:227	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	6	3	theme	cellulose	985:993	arg1	TOCN					1007:1010	TOCN	1007:1010	TOCN	1007:1010	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	6	3	theme	cellulose	985:993	arg1	nanofibers					995:1004	TEMPO-oxidized cellulose nanofibers	970:1004	TEMPO-oxidized cellulose nanofibers (TOCN)	970:1011	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	5	4	theme	excellent	771:779	arg1	activity					795:802	excellent antibacterial activity	771:802	excellent antibacterial activity	771:802	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	5	5	theme	bacteriostatic	938:951	arg1	%					962:962	a bacteriostatic rate > 90%	936:962	a bacteriostatic rate > 90%	936:962	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	6	6	theme	antibacterial	1089:1101	arg1	ability					1103:1109	obvious antibacterial ability	1081:1109	obvious antibacterial ability	1081:1109	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	6	7	theme	DEChN	1146:1150	arg1	role					1138:1141	the positive role	1125:1141	the positive role of DEChN and its amino groups	1125:1171	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	6	8	theme	MoS2QDs/TOCN	1049:1060	arg1	preparation					1034:1044	the preparation	1030:1044	the preparation of MoS2QDs/TOCN	1030:1060	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	5	9	theme	antibacterial	781:793	arg1	activity					795:802	excellent antibacterial activity	771:802	excellent antibacterial activity	771:802	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	4	10	theme	antibacterial	562:574	arg1	fixed					586:590	fixed	586:590	fixed	586:590	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	10	theme	antibacterial	562:574	arg1	agent					576:580	the antibacterial agent	558:580	the antibacterial agent	558:580	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	1	11	theme	Chitin	84:89	arg1	nanofiber					91:99	Chitin nanofiber	84:99	Chitin nanofiber	84:99	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	4	12	theme	survival	610:617	arg1	%					646:646	2.77%	642:646	2.77% (pH = 4)	642:655	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	12	theme	survival	610:617	arg1	rates					619:623	the survival rates	606:623	the survival rates of bacteria	606:635	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	13	theme	bacteria	628:635	arg1	%					646:646	2.77%	642:646	2.77% (pH = 4)	642:655	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	13	theme	bacteria	628:635	arg1	rates					619:623	the survival rates	606:623	the survival rates of bacteria	606:635	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	14	theme	DEChN	728:732	arg1	groups					734:739	the DEChN groups	724:739	the DEChN groups	724:739	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	1	15	theme	biological	209:218	arg1	biocompatibility					191:206	its inherent biocompatibility	178:206	its inherent biocompatibility	178:206	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	15	theme	biological	209:218	arg1	activity					220:227	biological activity	209:227	biological activity	209:227	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	6	16	theme	positive	1129:1136	arg1	role					1138:1141	the positive role	1125:1141	the positive role of DEChN and its amino groups	1125:1171	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	2	17	theme	hydrothermal	416:427	arg1	reactions					429:437	hydrothermal reactions	416:437	hydrothermal reactions	416:437	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	5	18	theme	acidic	810:815	arg1	pH < 5					829:834	pH < 5	829:834	pH < 5	829:834	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	5	18	theme	acidic	810:815	arg1	conditions					817:826	acidic conditions	810:826	acidic conditions (pH < 5)	810:835	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	6	19	theme	groups	1166:1171	arg1	role					1138:1141	the positive role	1125:1141	the positive role of DEChN and its amino groups	1125:1171	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	8	20	theme	current	1267:1273	arg1	study					1275:1279	The current study	1263:1279	The current study	1263:1279	The current study might inspire new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films.					
35398061	1	21	theme	potential	105:113	arg1	application					115:125	potential application	105:125	potential application as antibacterial nanocomposite material	105:165	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	3	22	theme	different	531:539	arg1	conditions					541:550	different conditions	531:550	different conditions	531:550	The antibacterial properties of MoS2QDs/DEChN against Escherichia coli were detected under different conditions.					
35398061	5	23	theme	antibacterial	879:891	arg1	activity					893:900	antibacterial activity	879:900	antibacterial activity close to neutral conditions	879:928	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	0	24	theme	improved	41:48	arg1	antibacterial					50:62	improved antibacterial	41:62	improved antibacterial	41:62	A MoS2QDs/chitin nanofiber composite for improved antibacterial and food packaging.					
35398061	2	25	theme	chitin	386:391	arg1	DEChNs					405:410	DEChNs	405:410	DEChNs	405:410	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	25	theme	chitin	386:391	arg1	nanofibers					393:402	partially deacetylated chitin nanofibers	363:402	partially deacetylated chitin nanofibers (DEChNs)	363:411	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	5	26	theme	DEChN	857:861	arg1	combination					842:852	the combination	838:852	the combination of DEChN and MoS2QDs	838:873	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	3	27	theme	MoS2QDs/DEChN	472:484	arg1	properties					458:467	The antibacterial properties	440:467	The antibacterial properties of MoS2QDs/DEChN against Escherichia coli	440:509	The antibacterial properties of MoS2QDs/DEChN against Escherichia coli were detected under different conditions.					
35398061	8	28	theme	MoS2QDs/DEChN	1356:1368	arg1	films					1370:1374	the prepared MoS2QDs/DEChN films	1343:1374	the prepared MoS2QDs/DEChN films	1343:1374	The current study might inspire new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films.					
35398061	1	29	theme	macromolecular	247:260	arg1	structure					262:270	macromolecular structure	247:270	macromolecular structure	247:270	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	3	30	theme	antibacterial	444:456	arg1	properties					458:467	The antibacterial properties	440:467	The antibacterial properties of MoS2QDs/DEChN against Escherichia coli	440:509	The antibacterial properties of MoS2QDs/DEChN against Escherichia coli were detected under different conditions.					
35398061	4	31	from	200 μg/mL	595:603	arg1	fixed					586:590	fixed	586:590	fixed	586:590	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	4	31	from	200 μg/mL	595:603	arg1	agent					576:580	the antibacterial agent	558:580	the antibacterial agent	558:580	When the antibacterial agent was fixed at 200 μg/mL, the survival rates of bacteria were 2.77% (pH = 4), 5.58% (pH = 5) and 7.83% (pH = 6), which were lower than those in the DEChN groups.					
35398061	1	32	contain	has	101:103	arg2	application					115:125	potential application	105:125	potential application as antibacterial nanocomposite material	105:165	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	32	contain	has	101:103	arg1	nanofiber					91:99	Chitin nanofiber	84:99	Chitin nanofiber	84:99	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	8	33	theme	new	1295:1297	arg1	ideas					1299:1303	new ideas	1295:1303	new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films	1295:1374	The current study might inspire new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films.					
35398061	1	34	theme	antibacterial	130:142	arg1	material					158:165	antibacterial nanocomposite material	130:165	antibacterial nanocomposite material	130:165	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	35	contain	containing	236:245	arg2	structure					262:270	macromolecular structure	247:270	macromolecular structure	247:270	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	35	contain	containing	236:245	arg1	biocompatibility					191:206	its inherent biocompatibility	178:206	its inherent biocompatibility	178:206	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	35	contain	containing	236:245	arg1	activity					220:227	biological activity	209:227	biological activity	209:227	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	35	contain	containing	236:245	arg2	effect					286:291	nano-size effect	276:291	nano-size effect	276:291	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	1	35	contain	containing	236:245	arg1	amino					230:234	amino	230:234	amino	230:234	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	2	36	theme	quantum	315:321	arg1	MoS2QDs					329:335	MoS2QDs	329:335	MoS2QDs	329:335	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	36	theme	quantum	315:321	arg1	dots					323:326	Molybdenum disulfide quantum dots	294:326	Molybdenum disulfide quantum dots (MoS2QDs)	294:336	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	1	37	theme	nanocomposite	144:156	arg1	material					158:165	antibacterial nanocomposite material	130:165	antibacterial nanocomposite material	130:165	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	8	38	theme	prepared	1347:1354	arg1	films					1370:1374	the prepared MoS2QDs/DEChN films	1343:1374	the prepared MoS2QDs/DEChN films	1343:1374	The current study might inspire new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films.					
35398061	6	39	theme	TEMPO-oxidized	970:983	arg1	TOCN					1007:1010	TOCN	1007:1010	TOCN	1007:1010	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	6	39	theme	TEMPO-oxidized	970:983	arg1	nanofibers					995:1004	TEMPO-oxidized cellulose nanofibers	970:1004	TEMPO-oxidized cellulose nanofibers (TOCN)	970:1011	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	8	40	theme	food	1319:1322	arg1	packaging					1324:1332	food packaging	1319:1332	food packaging	1319:1332	The current study might inspire new ideas for designing food packaging based on the prepared MoS2QDs/DEChN films.					
35398061	5	41	contain	had	767:769	arg1	DEChN					749:753	DEChN	749:753	DEChN	749:753	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	5	41	contain	had	767:769	arg2	activity					795:802	excellent antibacterial activity	771:802	excellent antibacterial activity	771:802	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	2	42	theme	disulfide	305:313	arg1	MoS2QDs					329:335	MoS2QDs	329:335	MoS2QDs	329:335	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	42	theme	disulfide	305:313	arg1	dots					323:326	Molybdenum disulfide quantum dots	294:326	Molybdenum disulfide quantum dots (MoS2QDs)	294:336	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	5	43	theme	neutral	911:917	arg1	conditions					919:928	neutral conditions	911:928	neutral conditions	911:928	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	2	44	theme	deacetylated	373:384	arg1	DEChNs					405:410	DEChNs	405:410	DEChNs	405:410	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	44	theme	deacetylated	373:384	arg1	nanofibers					393:402	partially deacetylated chitin nanofibers	363:402	partially deacetylated chitin nanofibers (DEChNs)	363:411	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	45	theme	Molybdenum	294:303	arg1	MoS2QDs					329:335	MoS2QDs	329:335	MoS2QDs	329:335	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	2	45	theme	Molybdenum	294:303	arg1	dots					323:326	Molybdenum disulfide quantum dots	294:326	Molybdenum disulfide quantum dots (MoS2QDs)	294:336	Molybdenum disulfide quantum dots (MoS2QDs) were uniformly bonded on partially deacetylated chitin nanofibers (DEChNs) by hydrothermal reactions.					
35398061	5	46	contain	had	875:877	arg1	combination					842:852	the combination	838:852	the combination of DEChN and MoS2QDs	838:873	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	5	46	contain	had	875:877	arg2	activity					893:900	antibacterial activity	879:900	antibacterial activity close to neutral conditions	879:928	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
35398061	6	47	theme	obvious	1081:1087	arg1	ability					1103:1109	obvious antibacterial ability	1081:1109	obvious antibacterial ability	1081:1109	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	1	48	theme	nano-size	276:284	arg1	effect					286:291	nano-size effect	276:291	nano-size effect	276:291	Chitin nanofiber has potential application as antibacterial nanocomposite material because of its inherent biocompatibility, biological activity, amino containing macromolecular structure and nano-size effect.					
35398061	0	49	theme	food	68:71	arg1	packaging					73:81	food packaging	68:81	food packaging	68:81	A MoS2QDs/chitin nanofiber composite for improved antibacterial and food packaging.					
35398061	6	50	theme	amino	1160:1164	arg1	groups					1166:1171	its amino groups	1156:1171	its amino groups	1156:1171	When TEMPO-oxidized cellulose nanofibers (TOCN) were applied for the preparation of MoS2QDs/TOCN, they did not show obvious antibacterial ability, which proved the positive role of DEChN and its amino groups.					
35398061	5	51	theme	MoS2QDs	867:873	arg1	combination					842:852	the combination	838:852	the combination of DEChN and MoS2QDs	838:873	Unlike DEChN, which only had excellent antibacterial activity under acidic conditions (pH < 5), the combination of DEChN and MoS2QDs had antibacterial activity close to neutral conditions, with a bacteriostatic rate > 90%.					
36005533	0	0	theme	Marinoepoxides	93:106	arg1	Enantioseparation					46:62	Enantioseparation	46:62	Enantioseparation of Newly Synthesized Racemic Marinoepoxides	46:106	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	3	1	theme	-2,3,3-trisubstituted	657:677	arg1	rac-6a-c					694:701	rac-6a-c	694:701	rac-6a-c	694:701	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	1	theme	-2,3,3-trisubstituted	657:677	arg1	rac-8a-c					750:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	1	theme	-2,3,3-trisubstituted	657:677	arg1	marinoepoxides					679:692	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	2	theme	stationary	979:988	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	2	theme	stationary	979:988	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	2	theme	stationary	979:988	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	3	dep	intermediate	296:307	arg1	marinoaziridines					352:367	marinoaziridines	352:367	marinoaziridines A and B	352:375	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	4	theme	cellulose	880:888	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	4	theme	cellulose	880:888	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	4	theme	cellulose	880:888	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	0	5	theme	Racemic	85:91	arg1	Marinoepoxides					93:106	Newly Synthesized Racemic Marinoepoxides	67:106	Newly Synthesized Racemic Marinoepoxides	67:106	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	2	6	theme	quinoline-2	570:580	arg1	4a-c					605:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c	552:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	552:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	5	7	theme	type/composition	1446:1461	arg1	structure					1413:1421	the structure	1409:1421	the structure of chiral selector and type/composition of the mobile phase	1409:1481	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	1	8	theme	1H	180:181	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	8	theme	1H	180:181	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	8	theme	1H	180:181	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	4	9	theme	liquid	1084:1089	arg1	HPLC					1107:1110	HPLC	1107:1110	HPLC	1107:1110	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	4	9	theme	liquid	1084:1089	arg1	chromatography					1091:1104	high-performance liquid chromatography	1067:1104	high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase	1067:1203	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	0	10	from	Application	0:10	arg1	Enantioseparation					46:62	Enantioseparation	46:62	Enantioseparation of Newly Synthesized Racemic Marinoepoxides	46:106	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	2	11	theme	corresponding	556:568	arg1	4a-c					605:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c	552:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	552:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	12	theme	CHIRAL	997:1002	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	12	theme	CHIRAL	997:1002	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	13	theme	3,5-dichlorophenylcarbamoyl	852:878	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	13	theme	3,5-dichlorophenylcarbamoyl	852:878	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	13	theme	3,5-dichlorophenylcarbamoyl	852:878	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	14	theme	chiral	813:818	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	14	theme	chiral	813:818	arg1	CSPs					839:842	CSPs	839:842	CSPs	839:842	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	14	theme	chiral	813:818	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	14	theme	chiral	813:818	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	15	theme	good	613:616	arg1	yield					618:622	good yield	613:622	good yield	613:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	16	theme	key	292:294	arg1	intermediate					296:307	the key intermediate	288:307	the key intermediate in the total synthesis of natural products marinoaziridines A and B	288:375	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	16	theme	key	292:294	arg1	rac-6a					280:285	Marinoepoxide rac-6a	266:285	Marinoepoxide rac-6a	266:285	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	17	theme	stationary	820:829	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	17	theme	stationary	820:829	arg1	CSPs					839:842	CSPs	839:842	CSPs	839:842	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	17	theme	stationary	820:829	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	17	theme	stationary	820:829	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	18	theme	4a-c	605:608	arg1	salt					503:506	the sulfonium salt 5 or 7	489:513	salt	503:506	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	19	theme	ART	1004:1006	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	19	theme	ART	1004:1006	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	20	theme	CHIRAL	908:913	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	20	theme	CHIRAL	908:913	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	21	theme	sulfonium	493:501	arg1	salt					503:506	the sulfonium salt 5 or 7	489:513	salt	503:506	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	22	theme	marinoepoxides	679:692	arg1	enantiomers					639:649	enantiomers	639:649	enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	639:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	23	theme	-one-4-carbaldehyde	585:603	arg1	4a-c					605:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c	552:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	552:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	24	theme	supercritical	1213:1225	arg1	SFC					1249:1251	SFC	1249:1251	SFC	1249:1251	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	4	24	theme	supercritical	1213:1225	arg1	chromatography					1233:1246	supercritical fluid chromatography	1213:1246	supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase	1213:1295	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	3	25	theme	type	808:811	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	25	theme	type	808:811	arg1	CSPs					839:842	CSPs	839:842	CSPs	839:842	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	25	theme	type	808:811	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	25	theme	type	808:811	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	26	theme	stationary	890:899	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	26	theme	stationary	890:899	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	26	theme	stationary	890:899	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	1	27	theme	-one	183:186	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	27	theme	-one	183:186	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	27	theme	-one	183:186	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	4	28	theme	Enantioseparation	1021:1037	arg1	conditions					1039:1048	Enantioseparation conditions	1021:1048	Enantioseparation conditions	1021:1048	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	5	29	theme	chiral	1426:1431	arg1	selector					1433:1440	chiral selector	1426:1440	chiral selector	1426:1440	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	5	30	theme	phase	1477:1481	arg1	selector					1433:1440	chiral selector	1426:1440	chiral selector	1426:1440	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	5	30	theme	phase	1477:1481	arg1	type/composition					1446:1461	type/composition	1446:1461	type/composition	1446:1461	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	1	31	theme	epoxide	188:194	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	31	theme	epoxide	188:194	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	31	theme	epoxide	188:194	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	3	32	theme	-trans-2,3-disubstituted	710:733	arg1	marinoepoxides					679:692	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	32	theme	-trans-2,3-disubstituted	710:733	arg1	rac-8a-c					750:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	33	theme	1H	582:583	arg1	4a-c					605:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c	552:608	the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	552:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	5	34	theme	selector	1433:1440	arg1	structure					1413:1421	the structure	1409:1421	the structure of chiral selector and type/composition of the mobile phase	1409:1481	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	2	35	theme	total	316:320	arg1	synthesis					322:330	the total synthesis	312:330	the total synthesis of natural products	312:350	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	36	theme	dimethyl	1119:1126	arg1	mixtures					1146:1153	dimethyl carbonate/alcohol mixtures	1119:1153	dimethyl carbonate/alcohol mixtures	1119:1153	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	1	37	theme	structures	196:205	arg1	series					152:157	the newly synthesized series	130:157	the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	130:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	0	38	theme	Chiral	21:26	arg1	Chromatography					28:41	Green Chiral Chromatography	15:41	Green Chiral Chromatography	15:41	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	3	39	theme	marinoepoxides	735:748	arg1	marinoepoxides					679:692	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	39	theme	marinoepoxides	735:748	arg1	rac-8a-c					750:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	4	40	theme	fluid	1227:1231	arg1	SFC					1249:1251	SFC	1249:1251	SFC	1249:1251	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	4	40	theme	fluid	1227:1231	arg1	chromatography					1233:1246	supercritical fluid chromatography	1213:1246	supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase	1213:1295	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	0	41	theme	Green	15:19	arg1	Chromatography					28:41	Green Chiral Chromatography	15:41	Green Chiral Chromatography	15:41	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	4	42	theme	mobile	1284:1289	arg1	phase					1291:1295	mobile phase	1284:1295	mobile phase	1284:1295	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	3	43	theme	ART	915:917	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	43	theme	ART	915:917	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	5	44	theme	examined	1305:1312	arg1	racemates					1314:1322	all examined racemates	1301:1322	all examined racemates	1301:1322	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	2	45	theme	products	343:350	arg1	synthesis					322:330	the total synthesis	312:330	the total synthesis of natural products	312:350	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	46	theme	carbonate/alcohol	1128:1144	arg1	mixtures					1146:1153	dimethyl carbonate/alcohol mixtures	1119:1153	dimethyl carbonate/alcohol mixtures	1119:1153	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	0	47	theme	Chromatography	28:41	arg1	Application					0:10	Application	0:10	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.	0:107	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	3	48	dep	marinoepoxides	679:692	arg1	rac-6a-c					694:701	rac-6a-c	694:701	rac-6a-c	694:701	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	48	dep	marinoepoxides	679:692	arg1	marinoepoxides					679:692	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	(±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	654:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	48	dep	marinoepoxides	679:692	arg1	rac-8a-c					750:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	(±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	707:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	49	theme	ylide	460:464	arg1	addition					436:443	addition	436:443	addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	436:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	5	50	theme	mobile	1470:1475	arg1	phase					1477:1481	the mobile phase	1466:1481	the mobile phase	1466:1481	In all examined racemates, enantioseparation was successfully achieved, but its efficiency largely depended on the structure of chiral selector and type/composition of the mobile phase.					
36005533	1	51	dep	structures	196:205	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	51	dep	structures	196:205	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	51	dep	structures	196:205	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	3	52	theme	3,5-dimethylphenylcarbamoyl	943:969	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	52	theme	3,5-dimethylphenylcarbamoyl	943:969	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	52	theme	3,5-dimethylphenylcarbamoyl	943:969	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	53	theme	structural	395:404	arg1	analogues					406:414	their structural analogues	389:414	their structural analogues	389:414	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	54	theme	achiral	452:458	arg1	ylide					460:464	the achiral ylide	448:464	the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield	448:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	55	theme	mobile	1192:1197	arg1	phase					1199:1203	mobile phase	1192:1203	mobile phase	1192:1203	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	2	56	from	4a-c	605:608	arg1	yield					618:622	good yield	613:622	good yield	613:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	57	from	salt	503:506	arg1	yield					618:622	good yield	613:622	good yield	613:622	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	58	theme	tris-	937:941	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	58	theme	tris-	937:941	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	58	theme	tris-	937:941	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	1	59	theme	synthesized	140:150	arg1	series					152:157	the newly synthesized series	130:157	the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	130:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	2	60	theme	double	537:542	arg1	bond					544:547	the carbon-oxygen double bond	519:547	the carbon-oxygen double bond	519:547	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	61	theme	CO2/alcohol	1260:1270	arg1	mixtures					1272:1279	CO2/alcohol mixtures	1260:1279	CO2/alcohol mixtures	1260:1279	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	1	62	theme	series	152:157	arg1	Enantioseparation					109:125	Enantioseparation	109:125	Enantioseparation	109:125	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	3	63	theme	tris-	846:850	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	63	theme	tris-	846:850	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	63	theme	tris-	846:850	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	64	theme	polysaccharide	793:806	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	64	theme	polysaccharide	793:806	arg1	CSPs					839:842	CSPs	839:842	CSPs	839:842	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	64	theme	polysaccharide	793:806	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	64	theme	polysaccharide	793:806	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	65	theme	carbon-oxygen	523:535	arg1	bond					544:547	the carbon-oxygen double bond	519:547	the carbon-oxygen double bond	519:547	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	3	66	dep	phases	831:836	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	66	dep	phases	831:836	arg1	Cellulose-SC					919:930	CHIRAL ART Cellulose-SC	908:930	CHIRAL ART Cellulose-SC	908:930	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	66	dep	phases	831:836	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	66	dep	phases	831:836	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	66	dep	phases	831:836	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	2	67	theme	Marinoepoxide	266:278	arg1	intermediate					296:307	the key intermediate	288:307	the key intermediate in the total synthesis of natural products marinoaziridines A and B	288:375	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	67	theme	Marinoepoxide	266:278	arg1	rac-6a					280:285	Marinoepoxide rac-6a	266:285	Marinoepoxide rac-6a	266:285	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	4	68	dep	80/20	1177:1181	arg1	v/v					1184:1186	v/v	1184:1186	v/v	1184:1186	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	2	69	from	yield	618:622	arg1	salt					503:506	the sulfonium salt 5 or 7	489:513	salt	503:506	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	2	70	theme	natural	335:341	arg1	products					343:350	natural products	335:350	natural products	335:350	Marinoepoxide rac-6a, the key intermediate in the total synthesis of natural products marinoaziridines A and B, as well as their structural analogues, was synthesized by addition of the achiral ylide generated in situ from the sulfonium salt 5 or 7, to the carbon-oxygen double bond of the corresponding quinoline-2(1H)-one-4-carbaldehyde 4a-c in good yield.					
36005533	0	71	theme	Synthesized	73:83	arg1	Marinoepoxides					93:106	Newly Synthesized Racemic Marinoepoxides	67:106	Newly Synthesized Racemic Marinoepoxides	67:106	Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides.					
36005533	4	72	theme	high-performance	1067:1082	arg1	HPLC					1107:1110	HPLC	1107:1110	HPLC	1107:1110	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	4	72	theme	high-performance	1067:1082	arg1	chromatography					1091:1104	high-performance liquid chromatography	1067:1104	high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase	1067:1203	Enantioseparation conditions were explored by high-performance liquid chromatography (HPLC) using dimethyl carbonate/alcohol mixtures and n-hexane/ethanol (80/20, v/v) as mobile phase, and by supercritical fluid chromatography (SFC) using CO2/alcohol mixtures as mobile phase.					
36005533	1	73	theme	novel	162:166	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	73	theme	novel	162:166	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	73	theme	novel	162:166	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	3	74	theme	enantiomers	639:649	arg1	Separation					625:634	Separation	625:634	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c	625:757	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	75	theme	amylose	971:977	arg1	Amylose-SA					1008:1017	CHIRAL ART Amylose-SA	997:1017	CHIRAL ART Amylose-SA	997:1017	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	75	theme	amylose	971:977	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	75	theme	amylose	971:977	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	1	76	theme	quinoline-2	168:178	arg1	structures					196:205	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c	162:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	76	theme	quinoline-2	168:178	arg1	rac-8a-c					220:227	rac-8a-c	220:227	rac-8a-c	220:227	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	1	76	theme	quinoline-2	168:178	arg1	rac-6a-c					207:214	rac-6a-c	207:214	rac-6a-c	207:214	Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a-c and rac-8a-c, named marinoepoxides, is described.					
36005533	3	77	theme	immobilized	781:791	arg1	phase					990:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase	937:994	tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	937:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	77	theme	immobilized	781:791	arg1	CSPs					839:842	CSPs	839:842	CSPs	839:842	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	77	theme	immobilized	781:791	arg1	phases					831:836	two immobilized polysaccharide type chiral stationary phases	777:836	two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA)	777:1018	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
36005533	3	77	theme	immobilized	781:791	arg1	phase					901:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase	846:905	tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC)	846:931	Separation of enantiomers of (±)-2,3,3-trisubstituted marinoepoxides rac-6a-c and (±)-trans-2,3-disubstituted marinoepoxides rac-8a-c was studied using two immobilized polysaccharide type chiral stationary phases (CSPs); tris-(3,5-dichlorophenylcarbamoyl)cellulose stationary phase (CHIRAL ART Cellulose-SC) and tris-(3,5-dimethylphenylcarbamoyl)amylose stationary phase (CHIRAL ART Amylose-SA).					
35065136	8	0	theme	adsorption	1114:1123	arg1	222.72 mg.g-1					1158:1170	222.72 mg.g-1	1158:1170	222.72 mg.g-1	1158:1170	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	8	0	theme	adsorption	1114:1123	arg1	capacity					1125:1132	the Langmuir maximum adsorption capacity	1093:1132	the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB	1093:1153	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	1	1	theme	pressure	262:269	arg1	method					278:283	wet spinning- environmental pressure drying method	234:283	wet spinning- environmental pressure drying method	234:283	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	8	2	theme	maximum	1106:1112	arg1	222.72 mg.g-1					1158:1170	222.72 mg.g-1	1158:1170	222.72 mg.g-1	1158:1170	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	8	2	theme	maximum	1106:1112	arg1	capacity					1125:1132	the Langmuir maximum adsorption capacity	1093:1132	the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB	1093:1153	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	2	3	theme	bath	346:349	arg1	concentration					317:329	concentration	317:329	concentration	317:329	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	2	3	theme	bath	346:349	arg1	type					308:311	type	308:311	type	308:311	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	9	4	theme	MB	1221:1222	arg1	adsorption					1224:1233	MB adsorption	1221:1233	MB adsorption	1221:1233	The CMC/GAs-30 show good recycle performance in MB adsorption.					
35065136	1	5	theme	drying	271:276	arg1	method					278:283	wet spinning- environmental pressure drying method	234:283	wet spinning- environmental pressure drying method	234:283	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	5	6	from	mechanisms	720:729	arg1	MB					761:762	MB	761:762	MB	761:762	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	5	6	from	mechanisms	720:729	arg1	methylene					745:753	methylene blue	745:758	methylene blue (MB)	745:763	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	10	7	from	water	1264:1268	arg1	MB					1256:1257	MB	1256:1257	MB from water	1256:1268	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	10	7	from	water	1264:1268	arg1	rate					1248:1251	The removal rate	1236:1251	The removal rate of MB from water by CMC/GAs-30	1236:1282	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	3	8	theme	universal	519:527	arg1	machine					537:543	electronic universal testing machine	508:543	electronic universal testing machine	508:543	The CMC/GAs was characterized through SEM, XRD, FI-IR, Raman, XPS, electronic universal testing machine and other methods.					
35065136	2	9	theme	type	308:311	arg1	influences					290:299	The influences	286:299	The influences of the type and concentration of coagulating bath on the formation of aerogel beads	286:383	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	0	10	theme	blue	107:110	arg1	methylene					97:105	methylene blue	97:110	methylene blue	97:110	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	3	11	theme	testing	529:535	arg1	machine					537:543	electronic universal testing machine	508:543	electronic universal testing machine	508:543	The CMC/GAs was characterized through SEM, XRD, FI-IR, Raman, XPS, electronic universal testing machine and other methods.					
35065136	5	12	theme	adsorption	709:718	arg1	mechanisms					720:729	the adsorption mechanisms	705:729	the adsorption mechanisms of CMC/GAs on methylene blue (MB)	705:763	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	10	13	from	rate	1248:1251	arg1	water					1264:1268	water	1264:1268	water	1264:1268	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	10	14	theme	MB	1256:1257	arg1	rate					1248:1251	The removal rate	1236:1251	The removal rate of MB from water by CMC/GAs-30	1236:1282	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	8	15	theme	CMC/GAs-30	1137:1146	arg1	222.72 mg.g-1					1158:1170	222.72 mg.g-1	1158:1170	222.72 mg.g-1	1158:1170	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	8	15	theme	CMC/GAs-30	1137:1146	arg1	capacity					1125:1132	the Langmuir maximum adsorption capacity	1093:1132	the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB	1093:1153	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	6	16	theme	Langmuir	854:861	arg1	model					863:867	the Langmuir model	850:867	the Langmuir model (R2 = 0.9964)	850:881	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	6	16	theme	Langmuir	854:861	arg1	R2 = 0.9964					870:880	R2 = 0.9964	870:880	R2 = 0.9964	870:880	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	5	17	theme	blue	755:758	arg1	MB					761:762	MB	761:762	MB	761:762	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	5	17	theme	blue	755:758	arg1	methylene					745:753	methylene blue	745:758	methylene blue (MB)	745:763	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	3	18	theme	electronic	508:517	arg1	machine					537:543	electronic universal testing machine	508:543	electronic universal testing machine	508:543	The CMC/GAs was characterized through SEM, XRD, FI-IR, Raman, XPS, electronic universal testing machine and other methods.					
35065136	3	19	theme	other	549:553	arg1	methods					555:561	other methods	549:561	other methods	549:561	The CMC/GAs was characterized through SEM, XRD, FI-IR, Raman, XPS, electronic universal testing machine and other methods.					
35065136	8	20	theme	experimental	1059:1070	arg1	conditions					1072:1081	the experimental conditions	1055:1081	the experimental conditions explored	1055:1090	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	2	21	theme	concentration	317:329	arg1	influences					290:299	The influences	286:299	The influences of the type and concentration of coagulating bath on the formation of aerogel beads	286:383	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	4	22	theme	3.83 mm	636:642	arg1	diameter					624:631	a mean pore diameter	612:631	a mean pore diameter	612:631	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	4	22	theme	3.83 mm	636:642	arg1	size					603:606	an average particle size	583:606	an average particle size	583:606	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	0	23	theme	cellulose/graphene	29:46	arg1	beads					66:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	9	24	theme	good	1193:1196	arg1	performance					1206:1216	good recycle performance	1193:1216	good recycle performance in MB adsorption	1193:1233	The CMC/GAs-30 show good recycle performance in MB adsorption.					
35065136	1	25	theme	Carboxymethyl	113:125	arg1	CMC/GAs					172:178	CMC/GAs	172:178	CMC/GAs	172:178	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	25	theme	Carboxymethyl	113:125	arg1	beads					165:169	Carboxymethyl cellulose/ graphene composite aerogel beads	113:169	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs)	113:179	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	26	theme	scaling-up	209:218	arg1	method					220:225	the easily scaling-up method	198:225	the easily scaling-up method	198:225	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	0	27	theme	carboxymethyl	15:27	arg1	beads					66:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	5	28	theme	analysis	673:680	arg1	results					682:688	The analysis results	669:688	The analysis results	669:688	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	6	29	dep	model	915:919	arg1	higher					928:933	higher	928:933	higher	928:933	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	1	30	theme	cellulose/	127:136	arg1	CMC/GAs					172:178	CMC/GAs	172:178	CMC/GAs	172:178	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	30	theme	cellulose/	127:136	arg1	beads					165:169	Carboxymethyl cellulose/ graphene composite aerogel beads	113:169	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs)	113:179	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	0	31	theme	aerogel	58:64	arg1	beads					66:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	2	32	dep	type	308:311	arg1	the					304:306	the	304:306	the	304:306	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	7	33	theme	adsorption	1011:1020	arg1	capacity					1022:1029	the equilibrium adsorption capacity	995:1029	the equilibrium adsorption capacity for MB	995:1036	When the particle size of CMC/GAs-30 decreases, the equilibrium adsorption capacity for MB increases.					
35065136	4	34	theme	pore	619:622	arg1	diameter					624:631	a mean pore diameter	612:631	a mean pore diameter	612:631	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	2	35	theme	forming	409:415	arg1	mechanism					417:425	the forming mechanism	405:425	the forming mechanism	405:425	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	0	36	theme	composite	48:56	arg1	beads					66:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	carboxymethyl cellulose/graphene composite aerogel beads	15:70	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	4	37	contain	has	579:581	arg1	CMC/GAs-30					568:577	The CMC/GAs-30	564:577	The CMC/GAs-30	564:577	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	4	37	contain	has	579:581	arg2	size					603:606	an average particle size	583:606	an average particle size	583:606	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	4	37	contain	has	579:581	arg2	diameter					624:631	a mean pore diameter	612:631	a mean pore diameter	612:631	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	4	38	theme	mean	614:617	arg1	diameter					624:631	a mean pore diameter	612:631	a mean pore diameter	612:631	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	6	39	theme	adsorption	819:828	arg1	process					830:836	The adsorption process	815:836	The adsorption process	815:836	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	7	40	theme	CMC/GAs-30	973:982	arg1	size					965:968	the particle size	952:968	the particle size of CMC/GAs-30	952:982	When the particle size of CMC/GAs-30 decreases, the equilibrium adsorption capacity for MB increases.					
35065136	1	41	theme	graphene	138:145	arg1	CMC/GAs					172:178	CMC/GAs	172:178	CMC/GAs	172:178	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	41	theme	graphene	138:145	arg1	beads					165:169	Carboxymethyl cellulose/ graphene composite aerogel beads	113:169	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs)	113:179	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	0	42	theme	beads	66:70	arg1	Preparation					0:10	Preparation	0:10	Preparation of carboxymethyl cellulose/graphene composite aerogel beads	0:70	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	0	42	theme	beads	66:70	arg1	adsorption					82:91	their adsorption	76:91	their adsorption for methylene blue	76:110	Preparation of carboxymethyl cellulose/graphene composite aerogel beads and their adsorption for methylene blue.					
35065136	7	43	theme	equilibrium	999:1009	arg1	capacity					1022:1029	the equilibrium adsorption capacity	995:1029	the equilibrium adsorption capacity for MB	995:1036	When the particle size of CMC/GAs-30 decreases, the equilibrium adsorption capacity for MB increases.					
35065136	1	44	dep	method	278:283	arg1	i.e.					228:231	i.e.	228:231	i.e.	228:231	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	7	45	theme	particle	956:963	arg1	size					965:968	the particle size	952:968	the particle size of CMC/GAs-30	952:982	When the particle size of CMC/GAs-30 decreases, the equilibrium adsorption capacity for MB increases.					
35065136	1	46	theme	composite	147:155	arg1	CMC/GAs					172:178	CMC/GAs	172:178	CMC/GAs	172:178	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	46	theme	composite	147:155	arg1	beads					165:169	Carboxymethyl cellulose/ graphene composite aerogel beads	113:169	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs)	113:179	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	2	47	from	influences	290:299	arg1	formation					358:366	the formation	354:366	the formation of aerogel beads	354:383	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	6	48	theme	kinetic	907:913	arg1	model					915:919	pseudo-second-order kinetic model	887:919	pseudo-second-order kinetic model (R2 is higher than 0.99)	887:944	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	4	49	theme	82 μm	648:652	arg1	diameter					624:631	a mean pore diameter	612:631	a mean pore diameter	612:631	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	4	49	theme	82 μm	648:652	arg1	size					603:606	an average particle size	583:606	an average particle size	583:606	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	1	50	theme	aerogel	157:163	arg1	CMC/GAs					172:178	CMC/GAs	172:178	CMC/GAs	172:178	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	1	50	theme	aerogel	157:163	arg1	beads					165:169	Carboxymethyl cellulose/ graphene composite aerogel beads	113:169	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs)	113:179	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	4	51	theme	average	586:592	arg1	size					603:606	an average particle size	583:606	an average particle size	583:606	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	9	52	from	performance	1206:1216	arg1	adsorption					1224:1233	MB adsorption	1221:1233	MB adsorption	1221:1233	The CMC/GAs-30 show good recycle performance in MB adsorption.					
35065136	10	53	theme	regeneration	1333:1344	arg1	cycles					1346:1351	30-times adsorption- regeneration cycles	1312:1351	30-times adsorption- regeneration cycles	1312:1351	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	2	54	theme	coagulating	334:344	arg1	bath					346:349	coagulating bath	334:349	coagulating bath	334:349	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	1	55	theme	wet	234:236	arg1	method					278:283	wet spinning- environmental pressure drying method	234:283	wet spinning- environmental pressure drying method	234:283	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	8	56	theme	Langmuir	1097:1104	arg1	222.72 mg.g-1					1158:1170	222.72 mg.g-1	1158:1170	222.72 mg.g-1	1158:1170	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	8	56	theme	Langmuir	1097:1104	arg1	capacity					1125:1132	the Langmuir maximum adsorption capacity	1093:1132	the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB	1093:1153	Under the experimental conditions explored, the Langmuir maximum adsorption capacity of CMC/GAs-30 for MB is 222.72 mg.g-1.					
35065136	10	57	theme	adsorption-	1321:1331	arg1	cycles					1346:1351	30-times adsorption- regeneration cycles	1312:1351	30-times adsorption- regeneration cycles	1312:1351	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	9	58	theme	recycle	1198:1204	arg1	performance					1206:1216	good recycle performance	1193:1216	good recycle performance in MB adsorption	1193:1233	The CMC/GAs-30 show good recycle performance in MB adsorption.					
35065136	5	59	theme	electrostatic	788:800	arg1	interaction					802:812	the electrostatic interaction	784:812	the electrostatic interaction	784:812	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	2	60	theme	beads	379:383	arg1	formation					358:366	the formation	354:366	the formation of aerogel beads	354:383	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	1	61	theme	spinning-	238:246	arg1	method					278:283	wet spinning- environmental pressure drying method	234:283	wet spinning- environmental pressure drying method	234:283	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
35065136	5	62	theme	CMC/GAs	734:740	arg1	mechanisms					720:729	the adsorption mechanisms	705:729	the adsorption mechanisms of CMC/GAs on methylene blue (MB)	705:763	The analysis results indicated that the adsorption mechanisms of CMC/GAs on methylene blue (MB) are mainly through the electrostatic interaction.					
35065136	6	63	theme	pseudo-second-order	887:905	arg1	model					915:919	pseudo-second-order kinetic model	887:919	pseudo-second-order kinetic model (R2 is higher than 0.99)	887:944	The adsorption process conforms to the Langmuir model (R2 = 0.9964) and pseudo-second-order kinetic model (R2 is higher than 0.99).					
35065136	4	64	theme	particle	594:601	arg1	size					603:606	an average particle size	583:606	an average particle size	583:606	The CMC/GAs-30 has an average particle size and a mean pore diameter of 3.83 mm and 82 μm, respectively.					
35065136	10	65	theme	30-times	1312:1319	arg1	cycles					1346:1351	30-times adsorption- regeneration cycles	1312:1351	30-times adsorption- regeneration cycles	1312:1351	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	2	66	theme	aerogel	371:377	arg1	beads					379:383	aerogel beads	371:383	aerogel beads	371:383	The influences of the type and concentration of coagulating bath on the formation of aerogel beads were discussed, and the forming mechanism was analyzed.					
35065136	10	67	theme	removal	1240:1246	arg1	rate					1248:1251	The removal rate	1236:1251	The removal rate of MB from water by CMC/GAs-30	1236:1282	The removal rate of MB from water by CMC/GAs-30 remained at about 90% after 30-times adsorption- regeneration cycles.					
35065136	1	68	theme	environmental	248:260	arg1	method					278:283	wet spinning- environmental pressure drying method	234:283	wet spinning- environmental pressure drying method	234:283	Carboxymethyl cellulose/ graphene composite aerogel beads (CMC/GAs) were prepared by the easily scaling-up method, i.e., wet spinning- environmental pressure drying method.					
37343353	12	0	theme	diet	2098:2101	arg1	group					2103:2107	the guar gum-supplemented diet group	2072:2107	the guar gum-supplemented diet group	2072:2107	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	5	1	theme	guar	660:663	arg1	gum					665:667	guar gum	660:667	guar gum	660:667	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	5	1	theme	guar	660:663	arg1	source					672:677	a source	670:677	a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation	670:778	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	13	2	theme	zootechnical	2237:2248	arg1	performance					2250:2260	zootechnical performance	2237:2260	zootechnical performance in broilers and results in a diet-induced dysbiosis	2237:2312	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	9	3	theme	diet-induced	1464:1475	arg1	dysbiosis					1477:1485	The mannan-rich diet-induced dysbiosis	1448:1485	The mannan-rich diet-induced dysbiosis	1448:1485	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	12	4	theme	branched-chain	2016:2029	arg1	acid					2037:2040	branched-chain fatty acid	2016:2040	branched-chain fatty acid	2016:2040	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	1	5	theme	broiler	206:212	arg1	ingredients					219:229	broiler feed ingredients	206:229	broiler feed ingredients	206:229	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	12	6	theme	acid	2037:2040	arg1	concentrations					2042:2055	cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations	1968:2055	cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations	1968:2055	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	9	7	theme	mannan-rich	1452:1462	arg1	dysbiosis					1477:1485	The mannan-rich diet-induced dysbiosis	1448:1485	The mannan-rich diet-induced dysbiosis	1448:1485	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	12	8	theme	protein	2166:2172	arg1	fermentation					2174:2185	reduced cecal protein fermentation	2152:2185	reduced cecal protein fermentation	2152:2185	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	11	9	theme	microbial	1846:1854	arg1	shifts					1856:1861	the main microbial shifts	1837:1861	the main microbial shifts induced by guar gum	1837:1881	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	2	10	theme	innate	312:317	arg1	response					326:333	innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity	312:440	response	326:333	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	9	11	theme	marked	1493:1498	arg1	effects					1500:1506	marked effects	1493:1506	marked effects on the cecal microbiota composition	1493:1542	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	12	12	theme	valeric	1998:2004	arg1	acid					2006:2009	valeric acid	1998:2009	valeric acid	1998:2009	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	2	13	with	diets	245:249	arg1	levels					261:266	high levels	256:266	high levels of galactomannans	256:284	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	5	14	theme	broiler	714:720	arg1	diets					722:726	broiler diets	714:726	broiler diets	714:726	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	6	15	theme	One-day-old	950:960	arg1	n = 756					980:986	n = 756	980:986	n = 756	980:986	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	15	theme	One-day-old	950:960	arg1	chickens					970:977	One-day-old broiler chickens	950:977	One-day-old broiler chickens (n = 756)	950:987	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	16	theme	guar	1082:1085	arg1	diet + β-mannanase					1104:1121	guar gum-supplemented diet + β-mannanase	1082:1121	guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1082:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	16	theme	guar	1082:1085	arg1	g/ton					1137:1141	Hemicell 330 g/ton	1124:1141	Hemicell 330 g/ton	1124:1141	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	16	theme	guar	1082:1085	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	10	17	theme	Clostridium	1646:1656	arg1	stricto					1664:1670	Clostridium sensu stricto 1	1646:1672	Clostridium sensu stricto 1	1646:1672	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	11	18	theme	guar	1874:1877	arg1	gum					1879:1881	guar gum	1874:1881	guar gum	1874:1881	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	9	19	theme	cecal	1515:1519	arg1	composition					1532:1542	the cecal microbiota composition	1511:1542	the cecal microbiota composition	1511:1542	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	5	20	dep	diets	722:726	arg1	either					729:734	either	729:734	either	729:734	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	12	21	theme	reduced	2152:2158	arg1	fermentation					2174:2185	reduced cecal protein fermentation	2152:2185	reduced cecal protein fermentation	2152:2185	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	11	22	theme	dietary	1792:1798	arg1	supplementation					1812:1826	dietary β-mannanase supplementation	1792:1826	dietary β-mannanase supplementation	1792:1826	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	5	23	theme	galactomannans	682:695	arg1	gum					665:667	guar gum	660:667	guar gum	660:667	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	5	23	theme	galactomannans	682:695	arg1	source					672:677	a source	670:677	a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation	670:778	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	5	24	theme	performance	924:934	arg1	improvements					936:947	performance improvements	924:947	performance improvements	924:947	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	8	25	theme	guar	1307:1310	arg1	gum					1312:1314	The guar gum	1303:1314	The guar gum supplementation	1303:1330	The guar gum supplementation decreased the zootechnical performance, and the β-mannanase supplementation restored performance to control levels.					
37343353	2	26	theme	high	256:259	arg1	levels					261:266	high levels	256:266	high levels of galactomannans	256:284	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	5	27	theme	microbiota	875:884	arg1	role					852:855	the potential role	838:855	the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements	838:947	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	12	28	theme	improved	2121:2128	arg1	digestion					2138:2146	improved protein digestion	2121:2146	improved protein digestion	2121:2146	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	7	29	theme	cecal	1202:1206	arg1	microbiome					1208:1217	ileal and cecal microbiome	1192:1217	ileal and cecal microbiome	1192:1217	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	12	30	theme	cecal	1968:1972	arg1	acid					2006:2009	valeric acid	1998:2009	valeric acid	1998:2009	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	5	31	theme	current	613:619	arg1	study					621:625	the current study	609:625	the current study	609:625	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	1	32	theme	abundant	168:175	arg1	Galactomannans					149:162	Galactomannans	149:162	Galactomannans	149:162	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	1	32	theme	abundant	168:175	arg1	polysaccharides					187:201	abundant nonstarch polysaccharides	168:201	abundant nonstarch polysaccharides in broiler feed ingredients	168:229	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	13	33	from	results	2278:2284	arg1	dysbiosis					2304:2312	a diet-induced dysbiosis	2289:2312	a diet-induced dysbiosis	2289:2312	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	7	34	theme	ileal	1192:1196	arg1	microbiome					1208:1217	ileal and cecal microbiome	1192:1217	ileal and cecal microbiome	1192:1217	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	14	35	theme	zootechnical	2387:2398	arg1	performance					2400:2410	zootechnical performance	2387:2410	zootechnical performance	2387:2410	β-Mannanase supplementation restored the gut microbiota composition and zootechnical performance to control levels.					
37343353	2	36	theme	excessive	414:422	arg1	viscosity					432:440	excessive digesta viscosity	414:440	excessive digesta viscosity	414:440	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	7	37	theme	morphometry	1179:1189	arg1	concentrations					1247:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	0	38	theme	Guar	0:3	arg1	gum					5:7	Guar gum	0:7	Guar gum as galactomannan source	0:31	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	8	39	theme	β-mannanase	1380:1390	arg1	supplementation					1392:1406	the β-mannanase supplementation	1376:1406	the β-mannanase supplementation	1376:1406	The guar gum supplementation decreased the zootechnical performance, and the β-mannanase supplementation restored performance to control levels.					
37343353	14	40	theme	gut	2356:2358	arg1	composition					2371:2381	the gut microbiota composition	2352:2381	the gut microbiota composition	2352:2381	β-Mannanase supplementation restored the gut microbiota composition and zootechnical performance to control levels.					
37343353	7	41	theme	zootechnical	1149:1160	arg1	performance					1162:1172	zootechnical performance	1149:1172	zootechnical performance	1149:1172	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	6	42	theme	guar	1044:1047	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	42	theme	guar	1044:1047	arg1	diet					1066:1069	guar gum-supplemented diet	1044:1069	guar gum-supplemented diet (1.7%)	1044:1076	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	42	theme	guar	1044:1047	arg1	%					1075:1075	1.7%	1072:1075	1.7%	1072:1075	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	4	43	theme	better	577:582	arg1	utilization					593:603	better nutrient utilization	577:603	better nutrient utilization	577:603	β-Mannanases are enzymes that can hydrolyze β-mannans, resulting in better nutrient utilization.					
37343353	5	44	theme	potential	842:850	arg1	role					852:855	the potential role	838:855	the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements	838:947	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	9	45	from	effects	1500:1506	arg1	composition					1532:1542	the cecal microbiota composition	1511:1542	the cecal microbiota composition	1511:1542	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	7	46	theme	time	1290:1293	arg1	points					1295:1300	different time points	1280:1300	different time points	1280:1300	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	10	47	theme	gum-supplemented	1554:1569	arg1	diet					1571:1574	The guar gum-supplemented diet	1545:1574	The guar gum-supplemented diet	1545:1574	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	11	48	theme	control	1900:1906	arg1	group					1908:1912	the control group	1896:1912	the control group	1896:1912	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	5	49	theme	microbiota	788:797	arg1	composition					799:809	the microbiota composition	784:809	the microbiota composition	784:809	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	13	50	from	performance	2250:2260	arg1	results					2278:2284	results	2278:2284	results	2278:2284	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	13	50	from	performance	2250:2260	arg1	broilers					2265:2272	broilers	2265:2272	broilers	2265:2272	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	2	51	theme	poor	348:351	arg1	performance					366:376	poor zootechnical performance	348:376	poor zootechnical performance	348:376	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	6	52	theme	gum-supplemented	1087:1102	arg1	diet + β-mannanase					1104:1121	guar gum-supplemented diet + β-mannanase	1082:1121	guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1082:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	52	theme	gum-supplemented	1087:1102	arg1	g/ton					1137:1141	Hemicell 330 g/ton	1124:1141	Hemicell 330 g/ton	1124:1141	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	52	theme	gum-supplemented	1087:1102	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	10	53	theme	cecal	1590:1594	arg1	abundance					1596:1604	the cecal abundance	1586:1604	the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella	1586:1698	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	2	54	theme	digesta	424:430	arg1	viscosity					432:440	excessive digesta viscosity	414:440	excessive digesta viscosity	414:440	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	2	55	theme	lipid	392:396	arg1	absorption					398:407	lipid absorption	392:407	lipid absorption	392:407	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	7	56	theme	acid	1242:1245	arg1	concentrations					1247:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	5	57	theme	β-mannanase	752:762	arg1	supplementation					764:778	β-mannanase supplementation	752:778	β-mannanase supplementation	752:778	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	9	58	with	dysbiosis	1477:1485	arg1	effects					1500:1506	marked effects	1493:1506	marked effects on the cecal microbiota composition	1493:1542	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	13	59	theme	galactomannan-rich	2205:2222	arg1	diet					2224:2227	a galactomannan-rich diet	2203:2227	a galactomannan-rich diet	2203:2227	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	12	60	theme	gum-supplemented	2081:2096	arg1	group					2103:2107	the guar gum-supplemented diet group	2072:2107	the guar gum-supplemented diet group	2072:2107	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	7	61	theme	short-chain	1224:1234	arg1	acid					1242:1245	short-chain fatty acid	1224:1245	short-chain fatty acid	1224:1245	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	10	62	theme	genera	1613:1618	arg1	abundance					1596:1604	the cecal abundance	1586:1604	the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella	1586:1698	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	5	63	theme	gum	665:667	arg1	effect					650:655	the effect	646:655	the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition	646:809	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	5	64	from	role	852:855	arg1	health					913:918	β-mannanase-induced gut health	889:918	β-mannanase-induced gut health	889:918	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	5	64	from	role	852:855	arg1	improvements					936:947	performance improvements	924:947	performance improvements	924:947	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	1	65	theme	nonstarch	177:185	arg1	Galactomannans					149:162	Galactomannans	149:162	Galactomannans	149:162	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	1	65	theme	nonstarch	177:185	arg1	polysaccharides					187:201	abundant nonstarch polysaccharides	168:201	abundant nonstarch polysaccharides in broiler feed ingredients	168:229	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	2	66	theme	immune	319:324	arg1	response					326:333	innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity	312:440	response	326:333	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	1	67	theme	feed	214:217	arg1	ingredients					219:229	broiler feed ingredients	206:229	broiler feed ingredients	206:229	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	12	68	theme	fatty	2031:2035	arg1	acid					2037:2040	branched-chain fatty acid	2016:2040	branched-chain fatty acid	2016:2040	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	5	69	theme	β-mannanase-induced	889:907	arg1	health					913:918	β-mannanase-induced gut health	889:918	β-mannanase-induced gut health	889:918	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	12	70	theme	cecal	2160:2164	arg1	fermentation					2174:2185	reduced cecal protein fermentation	2152:2185	reduced cecal protein fermentation	2152:2185	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	2	71	theme	zootechnical	353:364	arg1	performance					366:376	poor zootechnical performance	348:376	poor zootechnical performance	348:376	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	10	72	dep	genera	1613:1618	arg1	Escherichia-Shigella					1679:1698	Escherichia-Shigella	1679:1698	Escherichia-Shigella	1679:1698	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	10	72	dep	genera	1613:1618	arg1	Roseburia					1635:1643	Roseburia	1635:1643	Roseburia	1635:1643	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	10	72	dep	genera	1613:1618	arg1	stricto					1664:1670	Clostridium sensu stricto 1	1646:1672	Clostridium sensu stricto 1	1646:1672	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	6	73	theme	broiler	962:968	arg1	n = 756					980:986	n = 756	980:986	n = 756	980:986	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	73	theme	broiler	962:968	arg1	chickens					970:977	One-day-old broiler chickens	950:977	One-day-old broiler chickens (n = 756)	950:987	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	0	74	from	performance	63:73	arg1	chickens					86:93	broiler chickens	78:93	broiler chickens	78:93	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	10	75	theme	sensu	1658:1662	arg1	stricto					1664:1670	Clostridium sensu stricto 1	1646:1672	Clostridium sensu stricto 1	1646:1672	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	5	76	theme	gut	909:911	arg1	health					913:918	β-mannanase-induced gut health	889:918	β-mannanase-induced gut health	889:918	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	12	77	theme	acid	2006:2009	arg1	concentrations					2042:2055	cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations	1968:2055	cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations	1968:2055	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	12	78	theme	protein	2130:2136	arg1	digestion					2138:2146	improved protein digestion	2121:2146	improved protein digestion	2121:2146	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	2	79	theme	galactomannans	271:284	arg1	levels					261:266	high levels	256:266	high levels of galactomannans	256:284	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	9	80	theme	microbiota	1521:1530	arg1	composition					1532:1542	the cecal microbiota composition	1511:1542	the cecal microbiota composition	1511:1542	The mannan-rich diet-induced dysbiosis, with marked effects on the cecal microbiota composition.					
37343353	6	81	theme	control	1030:1036	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	81	theme	control	1030:1036	arg1	diet					1038:1041	control diet	1030:1041	control diet	1030:1041	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	2	82	dep	response	326:333	arg1	stimulation					335:345	stimulation	335:345	stimulation	335:345	In broilers, diets with high levels of galactomannans have been associated with innate immune response stimulation, poor zootechnical performance, nutrient and lipid absorption, and excessive digesta viscosity.					
37343353	13	83	from	broilers	2265:2272	arg1	dysbiosis					2304:2312	a diet-induced dysbiosis	2289:2312	a diet-induced dysbiosis	2289:2312	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	11	84	theme	β-mannanase	1800:1810	arg1	supplementation					1812:1826	dietary β-mannanase supplementation	1792:1826	dietary β-mannanase supplementation	1792:1826	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	7	85	theme	microbiome	1208:1217	arg1	concentrations					1247:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	5	86	theme	intestinal	864:873	arg1	microbiota					875:884	the intestinal microbiota	860:884	the intestinal microbiota	860:884	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	0	87	theme	broiler	78:84	arg1	chickens					86:93	broiler chickens	78:93	broiler chickens	78:93	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	12	88	theme	isobutyric	1974:1983	arg1	acid					2006:2009	valeric acid	1998:2009	valeric acid	1998:2009	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	1	89	from	polysaccharides	187:201	arg1	ingredients					219:229	broiler feed ingredients	206:229	broiler feed ingredients	206:229	Galactomannans are abundant nonstarch polysaccharides in broiler feed ingredients.					
37343353	8	90	theme	gum	1312:1314	arg1	supplementation					1316:1330	The guar gum supplementation	1303:1330	The guar gum supplementation	1303:1330	The guar gum supplementation decreased the zootechnical performance, and the β-mannanase supplementation restored performance to control levels.					
37343353	14	91	theme	control	2415:2421	arg1	levels					2423:2428	control levels	2415:2428	control levels	2415:2428	β-Mannanase supplementation restored the gut microbiota composition and zootechnical performance to control levels.					
37343353	11	92	theme	main	1841:1844	arg1	shifts					1856:1861	the main microbial shifts	1837:1861	the main microbial shifts induced by guar gum	1837:1881	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	12	93	theme	isovaleric	1986:1995	arg1	acid					2006:2009	valeric acid	1998:2009	valeric acid	1998:2009	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	6	94	theme	330	1133:1135	arg1	diet + β-mannanase					1104:1121	guar gum-supplemented diet + β-mannanase	1082:1121	guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1082:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	94	theme	330	1133:1135	arg1	g/ton					1137:1141	Hemicell 330 g/ton	1124:1141	Hemicell 330 g/ton	1124:1141	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	diet + β-mannanase					1104:1121	guar gum-supplemented diet + β-mannanase	1082:1121	guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1082:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	diet					1038:1041	control diet	1030:1041	control diet	1030:1041	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	g/ton					1137:1141	Hemicell 330 g/ton	1124:1141	Hemicell 330 g/ton	1124:1141	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	diet					1066:1069	guar gum-supplemented diet	1044:1069	guar gum-supplemented diet (1.7%)	1044:1076	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	95	dep	treatments	1018:1027	arg1	%					1075:1075	1.7%	1072:1075	1.7%	1072:1075	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	7	96	theme	gut	1175:1177	arg1	morphometry					1179:1189	gut morphometry	1175:1189	gut morphometry	1175:1189	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	12	97	theme	β-mannanase	1932:1942	arg1	supplementation					1944:1958	the β-mannanase supplementation	1928:1958	the β-mannanase supplementation	1928:1958	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	8	98	theme	zootechnical	1346:1357	arg1	performance					1359:1369	the zootechnical performance	1342:1369	the zootechnical performance	1342:1369	The guar gum supplementation decreased the zootechnical performance, and the β-mannanase supplementation restored performance to control levels.					
37343353	7	99	theme	performance	1162:1172	arg1	concentrations					1247:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations	1145:1260	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	14	100	theme	microbiota	2360:2369	arg1	composition					2371:2381	the gut microbiota composition	2352:2381	the gut microbiota composition	2352:2381	β-Mannanase supplementation restored the gut microbiota composition and zootechnical performance to control levels.					
37343353	0	101	theme	galactomannan	12:24	arg1	source					26:31	galactomannan source	12:31	galactomannan source	12:31	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	5	102	from	effect	650:655	arg1	composition					799:809	the microbiota composition	784:809	the microbiota composition	784:809	In the current study, we have evaluated the effect of guar gum, a source of galactomannans, supplemented to broiler diets, either with or without β-mannanase supplementation, on the microbiota composition, in an attempt to describe the potential role of the intestinal microbiota in β-mannanase-induced gut health and performance improvements.					
37343353	6	103	theme	gum-supplemented	1049:1064	arg1	treatments					1018:1027	3 treatments	1016:1027	3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1016:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	103	theme	gum-supplemented	1049:1064	arg1	diet					1066:1069	guar gum-supplemented diet	1044:1069	guar gum-supplemented diet (1.7%)	1044:1076	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	103	theme	gum-supplemented	1049:1064	arg1	%					1075:1075	1.7%	1072:1075	1.7%	1072:1075	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	4	104	theme	nutrient	584:591	arg1	utilization					593:603	better nutrient utilization	577:603	better nutrient utilization	577:603	β-Mannanases are enzymes that can hydrolyze β-mannans, resulting in better nutrient utilization.					
37343353	3	105	theme	gut	482:484	arg1	microbiome					486:495	the gut microbiome	478:495	the gut microbiome	478:495	However, data about its effects on the gut microbiome are scarce.					
37343353	7	106	theme	different	1280:1288	arg1	points					1295:1300	different time points	1280:1300	different time points	1280:1300	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	3	107	from	effects	467:473	arg1	microbiome					486:495	the gut microbiome	478:495	the gut microbiome	478:495	However, data about its effects on the gut microbiome are scarce.					
37343353	0	108	theme	dietary	99:105	arg1	β-mannanase					107:117	dietary β-mannanase	99:117	dietary β-mannanase	99:117	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	6	109	theme	Hemicell	1124:1131	arg1	diet + β-mannanase					1104:1121	guar gum-supplemented diet + β-mannanase	1082:1121	guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton)	1082:1142	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	6	109	theme	Hemicell	1124:1131	arg1	g/ton					1137:1141	Hemicell 330 g/ton	1124:1141	Hemicell 330 g/ton	1124:1141	One-day-old broiler chickens (n = 756) were randomly divided into 3 treatments: control diet, guar gum-supplemented diet (1.7%), or guar gum-supplemented diet + β-mannanase (Hemicell 330 g/ton).					
37343353	0	110	theme	gut	132:134	arg1	homeostasis					136:146	the gut homeostasis	128:146	the gut homeostasis	128:146	Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis.					
37343353	10	111	theme	guar	1549:1552	arg1	diet					1571:1574	The guar gum-supplemented diet	1545:1574	The guar gum-supplemented diet	1545:1574	The guar gum-supplemented diet increased the cecal abundance of the genera Lactobacillus, Roseburia, Clostridium sensu stricto 1, and Escherichia-Shigella, and decreased Intestinimonas, Alistipes, Butyricicoccus, and Faecalibacterium.					
37343353	11	112	theme	group	1908:1912	arg1	levels					1886:1891	levels	1886:1891	levels of the control group	1886:1912	In general, dietary β-mannanase supplementation restored the main microbial shifts induced by guar gum to levels of the control group.					
37343353	13	113	theme	diet-induced	2291:2302	arg1	dysbiosis					2304:2312	a diet-induced dysbiosis	2289:2312	a diet-induced dysbiosis	2289:2312	In conclusion, a galactomannan-rich diet impairs zootechnical performance in broilers and results in a diet-induced dysbiosis.					
37343353	8	114	theme	control	1432:1438	arg1	levels					1440:1445	control levels	1432:1445	control levels	1432:1445	The guar gum supplementation decreased the zootechnical performance, and the β-mannanase supplementation restored performance to control levels.					
37343353	12	115	theme	guar	2076:2079	arg1	group					2103:2107	the guar gum-supplemented diet group	2072:2107	the guar gum-supplemented diet group	2072:2107	In addition, the β-mannanase supplementation reduced cecal isobutyric, isovaleric, valeric acid, and branched-chain fatty acid concentrations as compared to the guar gum-supplemented diet group, suggesting improved protein digestion and reduced cecal protein fermentation.					
37343353	7	116	theme	fatty	1236:1240	arg1	acid					1242:1245	short-chain fatty acid	1224:1245	short-chain fatty acid	1224:1245	The zootechnical performance, gut morphometry, ileal and cecal microbiome, and short-chain fatty acid concentrations were evaluated at different time points.					
37343353	14	117	theme	β-Mannanase	2315:2325	arg1	supplementation					2327:2341	β-Mannanase supplementation	2315:2341	β-Mannanase supplementation	2315:2341	β-Mannanase supplementation restored the gut microbiota composition and zootechnical performance to control levels.					
36806955	2	0	theme	@	506:506	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	7	1	theme	CMC	1399:1401	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	4	2	theme	@	790:790	arg1	FB					797:798	CMC@Lig-3@FB	787:798	CMC@Lig-3@FB	787:798	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	6	3	theme	degradation	1129:1139	arg1	products					1141:1148	the BPA and degradation products	1117:1148	products	1141:1148	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	4	4	from	Adsorption	731:740	arg1	preparations					807:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations	752:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model	752:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	4	5	theme	@	796:796	arg1	FB					797:798	CMC@Lig-3@FB	787:798	CMC@Lig-3@FB	787:798	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	3	6	theme	degradation	579:589	arg1	%					634:634	87.8 and 89.6%	621:634	%	634:634	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	6	theme	degradation	579:589	arg1	rates					591:595	The degradation rates	575:595	The degradation rates of BPA	575:602	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	6	7	theme	freshwater	1208:1217	arg1	micro-crustacean					1219:1234	a freshwater micro-crustacean	1206:1234	(i) a freshwater micro-crustacean (Daphnia magna)	1202:1250	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	7	theme	freshwater	1208:1217	arg1	magna					1245:1249	Daphnia magna	1237:1249	Daphnia magna	1237:1249	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	7	theme	freshwater	1208:1217	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	7	8	theme	Fe	1392:1393	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	4	9	theme	isotherm	857:864	arg1	models					866:871	the Langmuir and Temkin isotherm models	833:871	models	866:871	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	9	10	theme	good	1695:1698	arg1	it					1681:1682	it	1681:1682	it	1681:1682	Thus, it could be a good candidate for environmentally safe biological methods.					
36806955	9	10	theme	good	1695:1698	arg1	candidate					1700:1708	a good candidate	1693:1708	a good candidate for environmentally safe biological methods	1693:1752	Thus, it could be a good candidate for environmentally safe biological methods.					
36806955	5	11	theme	Gibbs	931:935	arg1	energy					942:947	Gibbs free energy	931:947	Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K	931:1006	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	1	12	theme	free	391:394	arg1	system					424:429	a control system	414:429	a control system	414:429	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	1	12	theme	free	391:394	arg1	biomass					403:409	the free fungal biomass	387:409	the free fungal biomass	387:409	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	2	13	theme	@	512:512	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	1	14	used	used	320:323	arg2	formulations					302:313	The composite beads formulations	282:313	The composite beads formulations	282:313	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	2	15	theme	fungal	476:481	arg1	biomass					483:489	free fungal biomass	471:489	free fungal biomass	471:489	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	9	16	theme	safe	1730:1733	arg1	methods					1746:1752	environmentally safe biological methods	1714:1752	environmentally safe biological methods	1714:1752	Thus, it could be a good candidate for environmentally safe biological methods.					
36806955	6	17	theme	Turkish	1317:1323	arg1	wheat					1332:1336	a Turkish winter wheat	1315:1336	(iii) a Turkish winter wheat seed (Triticum aestivum L.)	1309:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	17	theme	Turkish	1317:1323	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	3	18	theme	87.8	621:624	arg1	%					634:634	87.8 and 89.6%	621:634	%	634:634	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	18	theme	87.8	621:624	arg1	rates					591:595	The degradation rates	575:595	The degradation rates of BPA	575:602	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	5	19	theme	free	937:940	arg1	energy					942:947	Gibbs free energy	931:947	Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K	931:1006	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	0	20	theme	Lig	268:270	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	20	theme	Lig	268:270	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	21	theme	carboxymethyl	166:178	arg1	beads					207:211	carboxymethyl cellulose-lignin composite beads	166:211	carboxymethyl cellulose-lignin composite beads	166:211	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	22	dep	biomass	768:774	arg1	FB					797:798	CMC@Lig-3@FB	787:798	CMC@Lig-3@FB	787:798	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	3	23	from	FB	685:686	arg1	reactor					708:714	a batch reactor	700:714	a batch reactor	700:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	0	24	theme	composite	197:205	arg1	beads					207:211	carboxymethyl cellulose-lignin composite beads	166:211	carboxymethyl cellulose-lignin composite beads	166:211	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	1	25	theme	A	373:373	arg1	degradation					348:358	degradation	348:358	degradation	348:358	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	1	25	theme	A	373:373	arg1	adsorption					333:342	adsorption	333:342	adsorption	333:342	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	0	26	theme	@	276:276	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	26	theme	@	276:276	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	3	27	theme	Fe	668:669	arg1	FB					685:686	Fe(III)CMC@Lig-3@FB	668:686	Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor	668:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	6	28	dep	wheat	1332:1336	arg1	Triticum					1344:1351	Triticum	1344:1351	Triticum	1344:1351	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	28	dep	wheat	1332:1336	arg1	iii					1310:1312	iii	1310:1312	iii	1310:1312	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	3	29	theme	89.6	630:633	arg1	%					634:634	87.8 and 89.6%	621:634	%	634:634	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	29	theme	89.6	630:633	arg1	rates					591:595	The degradation rates	575:595	The degradation rates of BPA	575:602	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	30	theme	Lig-3	679:683	arg1	FB					685:686	Fe(III)CMC@Lig-3@FB	668:686	Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor	668:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	4	31	theme	free	756:759	arg1	biomass					768:774	the free fungal biomass	752:774	the free fungal biomass	752:774	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	0	32	from	biomass	16:22	arg1	beads					67:71	carboxymethylcellulose-lignin composite beads	27:71	carboxymethylcellulose-lignin composite beads	27:71	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	33	theme	kinetic	902:908	arg1	model					910:914	the pseudo-second-order kinetic model	878:914	the pseudo-second-order kinetic model	878:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	5	34	theme	and - 25.8 kJ/mol	981:997	arg1	energy					942:947	Gibbs free energy	931:947	Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K	931:1006	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	1	35	theme	composite	286:294	arg1	beads					296:300	The composite beads	282:300	The composite beads formulations	282:313	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	3	36	theme	CMC	675:677	arg1	FB					685:686	Fe(III)CMC@Lig-3@FB	668:686	Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor	668:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	37	theme	free	644:647	arg1	biomass					656:662	the free fungal biomass	640:662	the free fungal biomass	640:662	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	0	38	theme	bisphenol	110:118	arg1	trogii					132:137	bisphenol A. Tramates trogii	110:137	bisphenol A. Tramates trogii	110:137	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	6	39	theme	Chlamydomonas	1278:1290	arg1	algae					1271:1275	a freshwater algae	1258:1275	(ii) a freshwater algae (Chlamydomonas reinhardti)	1253:1302	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	39	theme	Chlamydomonas	1278:1290	arg1	reinhardti					1292:1301	Chlamydomonas reinhardti	1278:1301	Chlamydomonas reinhardti	1278:1301	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	8	40	contain	had	1570:1572	arg1	system					1563:1568	the prepared composite bioactive system	1530:1568	the prepared composite bioactive system	1530:1568	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	8	40	contain	had	1570:1572	arg2	potential					1581:1589	a high potential	1574:1589	a high potential for degradation of BPA from an aqueous medium	1574:1635	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	2	41	theme	maximum	436:442	arg1	57.8					540:543	57.8	540:543	57.8	540:543	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	2	41	theme	maximum	436:442	arg1	capacity					455:462	The maximum adsorption capacity	432:462	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA	432:522	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	0	42	theme	Tramates	123:130	arg1	trogii					132:137	bisphenol A. Tramates trogii	110:137	bisphenol A. Tramates trogii	110:137	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	7	43	theme	pure	1499:1502	arg1	BPA					1504:1506	pure BPA	1499:1506	pure BPA	1499:1506	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	6	44	dep	algae	1271:1275	arg1	ii					1254:1255	ii	1254:1255	ii	1254:1255	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	0	45	theme	Tramates	0:7	arg1	biomass					16:22	Tramates trogii biomass	0:22	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass	0:145	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	46	theme	-CMC	263:266	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	46	theme	-CMC	263:266	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	47	theme	CMC	787:789	arg1	FB					797:798	CMC@Lig-3@FB	787:798	CMC@Lig-3@FB	787:798	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	5	48	theme	fungal	1028:1033	arg1	biomass					1035:1041	the free fungal biomass	1019:1041	the free fungal biomass	1019:1041	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	7	49	theme	toxic	1474:1478	arg1	effect					1480:1485	not any significant toxic effect	1454:1485	not any significant toxic effect	1454:1485	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	0	50	dep	adsorption	77:86	arg1	biomass					139:145	biomass	139:145	biomass	139:145	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	51	theme	biomass	768:774	arg1	preparations					807:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations	752:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model	752:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	0	52	theme	carboxymethylcellulose-lignin	27:55	arg1	beads					67:71	carboxymethylcellulose-lignin composite beads	27:71	carboxymethylcellulose-lignin composite beads	27:71	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	53	theme	Fe	780:781	arg1	preparations					807:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations	752:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model	752:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	1	54	theme	control	416:422	arg1	system					424:429	a control system	414:429	a control system	414:429	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	1	54	theme	control	416:422	arg1	biomass					403:409	the free fungal biomass	387:409	the free fungal biomass	387:409	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	8	55	theme	BPA	1610:1612	arg1	degradation					1595:1605	degradation	1595:1605	degradation of BPA	1595:1612	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	7	56	theme	@	1408:1408	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	5	57	theme	adsorption	952:961	arg1	and - 25.8 kJ/mol					981:997	adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol	952:997	adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol	952:997	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	7	58	theme	degradation	1429:1439	arg1	products					1441:1448	the degradation products	1425:1448	the degradation products	1425:1448	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	7	59	theme	@	1402:1402	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	5	60	theme	@	1058:1058	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	5	61	theme	ΔG°	964:966	arg1	and - 25.8 kJ/mol					981:997	adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol	952:997	adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol	952:997	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	2	62	dep	biomass	483:489	arg1	the					467:469	the	467:469	the	467:469	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	0	63	dep	Tramates	0:7	arg1	trogii					9:14	trogii	9:14	trogii	9:14	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	4	64	theme	Lig-3	791:795	arg1	FB					797:798	CMC@Lig-3@FB	787:798	CMC@Lig-3@FB	787:798	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	1	65	dep	adsorption	333:342	arg1	the					329:331	the	329:331	the	329:331	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	5	66	theme	@	1064:1064	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	6	67	theme	products	1141:1148	arg1	toxicities					1103:1112	the toxicities	1099:1112	the toxicities of the BPA and degradation products	1099:1148	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	0	68	dep	Fe	256:257	arg1	i.e.					250:253	i.e.	250:253	i.e.	250:253	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	2	69	theme	-CMC	502:505	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	6	70	dep	organisms	1191:1199	arg1	algae					1271:1275	a freshwater algae	1258:1275	(ii) a freshwater algae (Chlamydomonas reinhardti)	1253:1302	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	70	dep	organisms	1191:1199	arg1	wheat					1332:1336	a Turkish winter wheat	1315:1336	(iii) a Turkish winter wheat seed (Triticum aestivum L.)	1309:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	70	dep	organisms	1191:1199	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	70	dep	organisms	1191:1199	arg1	micro-crustacean					1219:1234	a freshwater micro-crustacean	1206:1234	(i) a freshwater micro-crustacean (Daphnia magna)	1202:1250	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	70	dep	organisms	1191:1199	arg1	reinhardti					1292:1301	Chlamydomonas reinhardti	1278:1301	Chlamydomonas reinhardti	1278:1301	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	70	dep	organisms	1191:1199	arg1	magna					1245:1249	Daphnia magna	1237:1249	Daphnia magna	1237:1249	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	0	71	theme	Fe	236:237	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	71	theme	Fe	236:237	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	5	72	theme	energy	942:947	arg1	values					921:926	The values	917:926	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.	917:1087	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	5	73	from	298 K	1002:1006	arg1	energy					942:947	Gibbs free energy	931:947	Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K	931:1006	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	5	73	from	298 K	1002:1006	arg1	values					921:926	The values	917:926	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.	917:1087	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	5	74	from	values	921:926	arg1	298 K					1002:1006	298 K	1002:1006	298 K	1002:1006	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	2	75	theme	FB	513:514	arg1	57.8					540:543	57.8	540:543	57.8	540:543	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	2	75	theme	FB	513:514	arg1	capacity					455:462	The maximum adsorption capacity	432:462	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA	432:522	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	7	76	contain	had	1450:1452	arg1	products					1441:1448	the degradation products	1425:1448	the degradation products	1425:1448	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	7	76	contain	had	1450:1452	arg2	effect					1480:1485	not any significant toxic effect	1454:1485	not any significant toxic effect	1454:1485	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	1	77	theme	fungal	396:401	arg1	system					424:429	a control system	414:429	a control system	414:429	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	1	77	theme	fungal	396:401	arg1	biomass					403:409	the free fungal biomass	387:409	the free fungal biomass	387:409	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	2	78	theme	Lig-3	507:511	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	2	79	theme	free	471:474	arg1	biomass					483:489	free fungal biomass	471:489	free fungal biomass	471:489	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	6	80	theme	winter	1325:1330	arg1	wheat					1332:1336	a Turkish winter wheat	1315:1336	(iii) a Turkish winter wheat seed (Triticum aestivum L.)	1309:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	80	theme	winter	1325:1330	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	5	81	from	BPA	1012:1014	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	4	82	theme	Temkin	850:855	arg1	models					866:871	the Langmuir and Temkin isotherm models	833:871	models	866:871	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	3	83	theme	BPA	600:602	arg1	%					634:634	87.8 and 89.6%	621:634	%	634:634	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	3	83	theme	BPA	600:602	arg1	rates					591:595	The degradation rates	575:595	The degradation rates of BPA	575:602	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	6	84	theme	test	1186:1189	arg1	micro-crustacean					1219:1234	a freshwater micro-crustacean	1206:1234	(i) a freshwater micro-crustacean (Daphnia magna)	1202:1250	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	84	theme	test	1186:1189	arg1	wheat					1332:1336	a Turkish winter wheat	1315:1336	(iii) a Turkish winter wheat seed (Triticum aestivum L.)	1309:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	84	theme	test	1186:1189	arg1	algae					1271:1275	a freshwater algae	1258:1275	(ii) a freshwater algae (Chlamydomonas reinhardti)	1253:1302	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	84	theme	test	1186:1189	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	8	85	theme	bioactive	1553:1561	arg1	system					1563:1568	the prepared composite bioactive system	1530:1568	the prepared composite bioactive system	1530:1568	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	0	86	theme	cellulose-lignin	180:195	arg1	beads					207:211	carboxymethyl cellulose-lignin composite beads	166:211	carboxymethyl cellulose-lignin composite beads	166:211	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	87	theme	@	267:267	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	87	theme	@	267:267	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	2	88	theme	Fe	495:496	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	1	89	theme	bisphenol	363:371	arg1	BPA					376:378	BPA	376:378	BPA	376:378	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	1	89	theme	bisphenol	363:371	arg1	A					373:373	bisphenol A	363:373	bisphenol A (BPA)	363:379	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	6	90	dep	micro-crustacean	1219:1234	arg1	i					1203:1203	i	1203:1203	i	1203:1203	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	2	91	theme	biomass	483:489	arg1	FB					513:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	the free fungal biomass and Fe(III)-CMC@Lig-3@FB	467:514	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	4	92	theme	pseudo-second-order	882:900	arg1	model					910:914	the pseudo-second-order kinetic model	878:914	the pseudo-second-order kinetic model	878:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	6	93	theme	Daphnia	1237:1243	arg1	micro-crustacean					1219:1234	a freshwater micro-crustacean	1206:1234	(i) a freshwater micro-crustacean (Daphnia magna)	1202:1250	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	93	theme	Daphnia	1237:1243	arg1	magna					1245:1249	Daphnia magna	1237:1249	Daphnia magna	1237:1249	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	94	dep	Triticum	1344:1351	arg1	L					1362:1362	L	1362:1362	Triticum aestivum L.	1344:1363	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	94	dep	Triticum	1344:1351	arg1	aestivum					1353:1360	Triticum aestivum L	1344:1362	Triticum aestivum L.	1344:1363	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	4	95	theme	BPA	745:747	arg1	Adsorption					731:740	Adsorption	731:740	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.	731:915	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	8	96	theme	composite	1543:1551	arg1	system					1563:1568	the prepared composite bioactive system	1530:1568	the prepared composite bioactive system	1530:1568	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	8	97	theme	prepared	1534:1541	arg1	system					1563:1568	the prepared composite bioactive system	1530:1568	the prepared composite bioactive system	1530:1568	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	3	98	theme	@	684:684	arg1	FB					685:686	Fe(III)CMC@Lig-3@FB	668:686	Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor	668:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	0	99	theme	A.	120:121	arg1	trogii					132:137	bisphenol A. Tramates trogii	110:137	bisphenol A. Tramates trogii	110:137	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	1	100	theme	beads	296:300	arg1	formulations					302:313	The composite beads formulations	282:313	The composite beads formulations	282:313	The composite beads formulations were used for the adsorption and degradation of bisphenol A (BPA) using the free fungal biomass as a control system.					
36806955	3	101	theme	@	678:678	arg1	FB					685:686	Fe(III)CMC@Lig-3@FB	668:686	Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor	668:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	2	102	theme	adsorption	444:453	arg1	57.8					540:543	57.8	540:543	57.8	540:543	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	2	102	theme	adsorption	444:453	arg1	capacity					455:462	The maximum adsorption capacity	432:462	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA	432:522	The maximum adsorption capacity of the free fungal biomass and Fe(III)-CMC@Lig-3@FB for BPA was found to be 57.8 and 95.6, mg/g, respectively.					
36806955	5	103	theme	Fe	1047:1048	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	3	104	theme	fungal	649:654	arg1	biomass					656:662	the free fungal biomass	640:662	the free fungal biomass	640:662	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	0	105	theme	trogii	132:137	arg1	biodegradation					92:105	biodegradation	92:105	biodegradation of bisphenol A. Tramates trogii	92:137	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	105	theme	trogii	132:137	arg1	adsorption					77:86	adsorption	77:86	adsorption	77:86	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	8	106	theme	aqueous	1622:1628	arg1	medium					1630:1635	an aqueous medium	1619:1635	an aqueous medium	1619:1635	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	0	107	with	cross-linking	217:229	arg1	FB					277:278	-CMC@Lig(1-4)@FB	263:278	-CMC@Lig(1-4)@FB	263:278	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	0	107	with	cross-linking	217:229	arg1	ions					244:247	Fe(III) ions	236:247	Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB)	236:279	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	6	108	theme	BPA	1121:1123	arg1	products					1141:1148	the BPA and degradation products	1117:1148	products	1141:1148	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	9	109	theme	biological	1735:1744	arg1	methods					1746:1752	environmentally safe biological methods	1714:1752	environmentally safe biological methods	1714:1752	Thus, it could be a good candidate for environmentally safe biological methods.					
36806955	6	110	theme	freshwater	1260:1269	arg1	algae					1271:1275	a freshwater algae	1258:1275	(ii) a freshwater algae (Chlamydomonas reinhardti)	1253:1302	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	110	theme	freshwater	1260:1269	arg1	reinhardti					1292:1301	Chlamydomonas reinhardti	1278:1301	Chlamydomonas reinhardti	1278:1301	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	110	theme	freshwater	1260:1269	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	5	111	theme	free	1023:1026	arg1	biomass					1035:1041	the free fungal biomass	1019:1041	the free fungal biomass	1019:1041	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	7	112	theme	significant	1462:1472	arg1	effect					1480:1485	not any significant toxic effect	1454:1485	not any significant toxic effect	1454:1485	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	8	113	theme	toxic	1655:1659	arg1	end-products					1661:1672	toxic end-products	1655:1672	toxic end-products	1655:1672	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	7	114	with	treatment	1373:1381	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	5	115	theme	biomass	1035:1041	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	0	116	theme	composite	57:65	arg1	beads					67:71	carboxymethylcellulose-lignin composite beads	27:71	carboxymethylcellulose-lignin composite beads	27:71	Tramates trogii biomass in carboxymethylcellulose-lignin composite beads for adsorption and biodegradation of bisphenol A. Tramates trogii biomass was immobilized in carboxymethyl cellulose-lignin composite beads via cross-linking with Fe(III) ions (i.e., Fe(III)-CMC@Lig(1-4)@FB).					
36806955	3	117	theme	batch	702:706	arg1	reactor					708:714	a batch reactor	700:714	a batch reactor	700:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	4	118	theme	fungal	761:766	arg1	biomass					768:774	the free fungal biomass	752:774	the free fungal biomass	752:774	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	5	119	theme	FB	1065:1066	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	8	120	from	medium	1630:1635	arg1	potential					1581:1589	a high potential	1574:1589	a high potential for degradation of BPA from an aqueous medium	1574:1635	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36806955	3	121	from	%	634:634	arg1	reactor					708:714	a batch reactor	700:714	a batch reactor	700:714	The degradation rates of BPA were found to be 87.8 and 89.6% for the free fungal biomass and Fe(III)CMC@Lig-3@FB for 72 h in a batch reactor, respectively.					
36806955	6	122	theme	different	1176:1184	arg1	micro-crustacean					1219:1234	a freshwater micro-crustacean	1206:1234	(i) a freshwater micro-crustacean (Daphnia magna)	1202:1250	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	122	theme	different	1176:1184	arg1	wheat					1332:1336	a Turkish winter wheat	1315:1336	(iii) a Turkish winter wheat seed (Triticum aestivum L.)	1309:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	122	theme	different	1176:1184	arg1	algae					1271:1275	a freshwater algae	1258:1275	(ii) a freshwater algae (Chlamydomonas reinhardti)	1253:1302	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	6	122	theme	different	1176:1184	arg1	organisms					1191:1199	three different test organisms	1170:1199	three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.)	1170:1364	Moreover, the toxicities of the BPA and degradation products were evaluated with three different test organisms: (i) a freshwater micro-crustacean (Daphnia magna), (ii) a freshwater algae (Chlamydomonas reinhardti), and (iii) a Turkish winter wheat seed (Triticum aestivum L.).					
36806955	7	123	theme	FB	1409:1410	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	4	124	theme	fungal	800:805	arg1	preparations					807:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations	752:818	the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model	752:914	Adsorption of BPA on the free fungal biomass and Fe(III)CMC@Lig-3@FB fungal preparations described by the Langmuir and Temkin isotherm models, and the pseudo-second-order kinetic model.					
36806955	5	125	theme	-CMC	1054:1057	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	7	126	theme	Lig-3	1403:1407	arg1	formulation					1412:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	the Fe(III)CMC@Lig-3@FB formulation	1388:1422	After treatment with the Fe(III)CMC@Lig-3@FB formulation, the degradation products had not any significant toxic effect compared to pure BPA.					
36806955	5	127	theme	Lig-3	1059:1063	arg1	beads					1068:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads	1019:1072	The values of Gibbs free energy of adsorption (ΔG°) were - 20.7 and - 25.8 kJ/mol at 298 K for BPA on the free fungal biomass and Fe(III)-CMC@Lig-3@FB beads, respectively.					
36806955	8	128	theme	high	1576:1579	arg1	potential					1581:1589	a high potential	1574:1589	a high potential for degradation of BPA from an aqueous medium	1574:1635	This work shows that the prepared composite bioactive system had a high potential for degradation of BPA from an aqueous medium without producing toxic end-products.					
36414610	7	0	theme	ALGNP	1130:1134	arg1	CTAC					1136:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	0	theme	ALGNP	1130:1134	arg1	nanogel					1111:1117	sodium borohydride (SBH)-fabricated nanogel	1075:1117	sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC)	1075:1140	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	5	1	theme	copper	626:631	arg1	nanogel					670:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	10	2	theme	PDA	1560:1562	arg1	gel					1575:1577	The PDA containing gel	1556:1577	The PDA containing gel	1556:1577	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	9	3	theme	SBH-CuONP	1512:1520	arg1	CTAC					1528:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	7	4	contain	had	912:914	arg2	Cu2+					925:928	a higher Cu2+	916:928	a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper	916:1190	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	4	contain	had	912:914	arg1	nanogel					863:869	The composite nanogel	849:869	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC)	849:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	5	theme	disease	1015:1021	arg1	control					1023:1029	better disease control	1008:1029	better disease control	1008:1029	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	10	6	theme	anti-erosion	1595:1606	arg1	ability					1608:1614	an improved anti-erosion ability	1583:1614	an improved anti-erosion ability	1583:1614	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	9	7	theme	ALGNP	1522:1526	arg1	CTAC					1528:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	6	8	dep	in	731:732	arg1	situ					734:737	situ	734:737	situ	734:737	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	2	9	theme	wildfire	159:166	arg1	disease					168:174	The wildfire disease	155:174	The wildfire disease on tobacco	155:185	BACKGROUND The wildfire disease on tobacco can seriously hinder plants.					
36414610	4	10	theme	summer	372:377	arg1	rains					379:383	summer rains	372:383	summer rains which washes away most copper (Cu)-based bactericides	372:437	However, the disease usually occurs after summer rains which washes away most copper (Cu)-based bactericides, allowing the disease to invade.					
36414610	11	11	theme	composite	1647:1655	arg1	nanogel					1657:1663	This new composite nanogel	1638:1663	This new composite nanogel	1638:1663	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	9	12	theme	thiodiazole	1536:1546	arg1	copper					1548:1553	thiodiazole copper	1536:1553	thiodiazole copper	1536:1553	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	11	13	theme	high	1671:1674	arg1	potential					1676:1684	a high potential	1669:1684	a high potential for wildfire disease control	1669:1713	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	7	14	theme	pathogen	959:966	arg1	membrane					968:975	the pathogen membrane	955:975	the pathogen membrane	955:975	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	5	15	theme	disease	520:526	arg1	control					528:534	high disease control	515:534	high disease control	515:534	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	3	16	theme	agriculture	306:316	arg1	production					318:327	threat agriculture production	299:327	threat agriculture production	299:327	Meanwhile, its pathogen, Pseudomonas syringae, can also infect over 200 plants and threat agriculture production.					
36414610	8	17	theme	rain	1311:1314	arg1	simulations					1322:1332	five rain event simulations	1306:1332	five rain event simulations	1306:1332	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	5	18	theme	CuONP	653:657	arg1	nanogel					670:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	7	19	theme	better	1008:1013	arg1	control					1023:1029	better disease control	1008:1029	better disease control	1008:1029	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	5	20	theme	composite	660:668	arg1	nanogel					670:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	5	21	theme	new	498:500	arg1	nanogel					502:508	a new nanogel	496:508	a new nanogel with high disease control and anti-erosion ability	496:559	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	4	22	theme	-based	419:424	arg1	bactericides					426:437	away most copper (Cu)-based bactericides	398:437	away most copper (Cu)-based bactericides	398:437	However, the disease usually occurs after summer rains which washes away most copper (Cu)-based bactericides, allowing the disease to invade.					
36414610	8	23	theme	PDA-CuONP	1197:1205	arg1	CTAC					1213:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	7	24	theme	@	1129:1129	arg1	CTAC					1136:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	24	theme	@	1129:1129	arg1	nanogel					1111:1117	sodium borohydride (SBH)-fabricated nanogel	1075:1117	sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC)	1075:1140	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	25	theme	ALGNP	900:904	arg1	CTAC					906:909	PDA-CuONP@ALGNP@CTAC	890:909	PDA-CuONP@ALGNP@CTAC	890:909	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	25	theme	ALGNP	900:904	arg1	PDA					885:887	PDA	885:887	PDA (PDA-CuONP@ALGNP@CTAC)	885:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	26	dep	rate	940:943	arg1	damaging					946:953	damaging	946:953	damaging	946:953	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	3	27	theme	threat	299:304	arg1	production					318:327	threat agriculture production	299:327	threat agriculture production	299:327	Meanwhile, its pathogen, Pseudomonas syringae, can also infect over 200 plants and threat agriculture production.					
36414610	8	28	theme	ALGNP	1207:1211	arg1	CTAC					1213:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	7	29	theme	PDA-CuONP	890:898	arg1	CTAC					906:909	PDA-CuONP@ALGNP@CTAC	890:909	PDA-CuONP@ALGNP@CTAC	890:909	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	29	theme	PDA-CuONP	890:898	arg1	PDA					885:887	PDA	885:887	PDA (PDA-CuONP@ALGNP@CTAC)	885:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	5	30	theme	nanoparticle	639:650	arg1	nanogel					670:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	8	31	contain	had	1218:1220	arg2	ability					1242:1248	a high anti-erosion ability	1222:1248	a high anti-erosion ability	1222:1248	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	8	31	contain	had	1218:1220	arg1	CTAC					1213:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	0	32	theme	synringae	111:119	arg1	pv					121:122	Pseudomonas synringae pv	99:122	Pseudomonas synringae pv	99:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	9	33	theme	composite	1396:1404	arg1	nanogel					1406:1412	CuONP composite nanogel	1390:1412	CuONP composite nanogel	1390:1412	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	6	34	theme	RESULTS	679:685	arg1	polycation					711:720	a polycation	709:720	a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work	709:846	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	6	34	theme	RESULTS	679:685	arg1	PDA					701:703	PDA	701:703	PDA	701:703	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	6	34	theme	RESULTS	679:685	arg1	Polydopamine					687:698	RESULTS Polydopamine	679:698	RESULTS Polydopamine (PDA)	679:704	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	8	35	theme	anti-erosion	1229:1240	arg1	ability					1242:1248	a high anti-erosion ability	1222:1248	a high anti-erosion ability	1222:1248	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	7	36	theme	composite	853:861	arg1	nanogel					863:869	The composite nanogel	849:869	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC)	849:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	0	37	theme	polydopamine	15:26	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of polydopamine	0:26	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	9	38	theme	releasing	1438:1446	arg1	rate					1448:1451	the Cu2+ releasing rate	1429:1451	the Cu2+ releasing rate	1429:1451	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	0	39	theme	CuO	36:38	arg1	nanogels					72:79	CuO nanoparticle-alginate composite nanogels	36:79	CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv	36:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	7	40	theme	thiodiazole	1173:1183	arg1	copper					1185:1190	thiodiazole copper	1173:1190	thiodiazole copper	1173:1190	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	40	theme	thiodiazole	1173:1183	arg1	bactericide					1160:1170	the commercial bactericide	1145:1170	the commercial bactericide	1145:1170	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	11	41	theme	disease	1699:1705	arg1	control					1707:1713	wildfire disease control	1690:1713	wildfire disease control	1690:1713	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	0	42	theme	composite	62:70	arg1	nanogels					72:79	CuO nanoparticle-alginate composite nanogels	36:79	CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv	36:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	9	43	dep	CONCLUSION	1335:1344	arg1	increase					1420:1427	increase	1420:1427	increase	1420:1427	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	1	44	from	tabaci	125:130	arg1	tobacco					135:141	tobacco	135:141	tobacco	135:141	tabaci in tobacco.					
36414610	9	45	theme	disease	1476:1482	arg1	management					1484:1493	improved disease management	1467:1493	improved disease management	1467:1493	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	6	46	from	reduction	739:747	arg1	nanogels					770:777	alginate nanogels	761:777	alginate nanogels	761:777	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	11	47	theme	agricultural	1726:1737	arg1	production					1739:1748	agricultural production	1726:1748	agricultural production	1726:1748	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	5	48	with	nanogel	502:508	arg1	control					528:534	high disease control	515:534	high disease control	515:534	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	5	48	with	nanogel	502:508	arg1	ability					553:559	anti-erosion ability	540:559	anti-erosion ability	540:559	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	10	49	theme	containing	1564:1573	arg1	gel					1575:1577	The PDA containing gel	1556:1577	The PDA containing gel	1556:1577	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	7	50	theme	@	1135:1135	arg1	CTAC					1136:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	50	theme	@	1135:1135	arg1	nanogel					1111:1117	sodium borohydride (SBH)-fabricated nanogel	1075:1117	sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC)	1075:1140	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	5	51	theme	oxide	633:637	arg1	nanogel					670:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	the copper oxide nanoparticle (CuONP) composite nanogel	622:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	6	52	theme	alginate	761:768	arg1	nanogels					770:777	alginate nanogels	761:777	alginate nanogels	761:777	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	7	53	theme	@	905:905	arg1	CTAC					906:909	PDA-CuONP@ALGNP@CTAC	890:909	PDA-CuONP@ALGNP@CTAC	890:909	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	53	theme	@	905:905	arg1	PDA					885:887	PDA	885:887	PDA (PDA-CuONP@ALGNP@CTAC)	885:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	9	54	theme	@	1521:1521	arg1	CTAC					1528:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	6	55	theme	CuONP	752:756	arg1	reduction					739:747	both in situ reduction	726:747	both in situ reduction of CuONP in alginate nanogels	726:777	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	10	56	theme	improved	1586:1593	arg1	ability					1608:1614	an improved anti-erosion ability	1583:1614	an improved anti-erosion ability	1583:1614	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	7	57	theme	growth	1041:1046	arg1	promotion					1048:1056	plant growth promotion	1035:1056	plant growth promotion	1035:1056	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	9	58	theme	@	1527:1527	arg1	CTAC					1528:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	SBH-CuONP@ALGNP@CTAC	1512:1531	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	5	59	theme	nanogel	670:676	arg1	performance					607:617	the performance	603:617	the performance of the copper oxide nanoparticle (CuONP) composite nanogel	603:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	6	60	theme	in	731:732	arg1	reduction					739:747	both in situ reduction	726:747	both in situ reduction of CuONP in alginate nanogels	726:777	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	10	61	theme	water	1620:1624	arg1	resistance					1626:1635	water resistance	1620:1635	water resistance	1620:1635	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	11	62	theme	new	1643:1645	arg1	nanogel					1657:1663	This new composite nanogel	1638:1663	This new composite nanogel	1638:1663	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	8	63	theme	event	1316:1320	arg1	simulations					1322:1332	five rain event simulations	1306:1332	five rain event simulations	1306:1332	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	2	64	from	disease	168:174	arg1	tobacco					179:185	tobacco	179:185	tobacco	179:185	BACKGROUND The wildfire disease on tobacco can seriously hinder plants.					
36414610	8	65	theme	leaf	1282:1285	arg1	surface					1287:1293	the leaf surface	1278:1293	the leaf surface	1278:1293	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	5	66	theme	anti-erosion	540:551	arg1	ability					553:559	anti-erosion ability	540:559	anti-erosion ability	540:559	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	9	67	theme	polycations	1362:1372	arg1	addition					1350:1357	The addition	1346:1357	The addition of polycations (like PDA) into CuONP composite nanogel	1346:1412	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	10	68	contain	had	1579:1581	arg2	ability					1608:1614	an improved anti-erosion ability	1583:1614	an improved anti-erosion ability	1583:1614	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	10	68	contain	had	1579:1581	arg2	resistance					1626:1635	water resistance	1620:1635	water resistance	1620:1635	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	10	68	contain	had	1579:1581	arg1	gel					1575:1577	The PDA containing gel	1556:1577	The PDA containing gel	1556:1577	The PDA containing gel had an improved anti-erosion ability and water resistance.					
36414610	7	69	theme	SBH-CuONP	1120:1128	arg1	CTAC					1136:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	69	theme	SBH-CuONP	1120:1128	arg1	nanogel					1111:1117	sodium borohydride (SBH)-fabricated nanogel	1075:1117	sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC)	1075:1140	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	70	theme	-fabricated	1099:1109	arg1	CTAC					1136:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	SBH-CuONP@ALGNP@CTAC	1120:1139	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	70	theme	-fabricated	1099:1109	arg1	nanogel					1111:1117	sodium borohydride (SBH)-fabricated nanogel	1075:1117	sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC)	1075:1140	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	0	71	theme	Pseudomonas	99:109	arg1	pv					121:122	Pseudomonas synringae pv	99:122	Pseudomonas synringae pv	99:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	12	72	theme	Chemical	1769:1776	arg1	Industry					1778:1785	Chemical Industry	1769:1785	Chemical Industry	1769:1785	© 2022 Society of Chemical Industry.					
36414610	5	73	theme	high	515:518	arg1	control					528:534	high disease control	515:534	high disease control	515:534	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	5	74	from	effects	575:581	arg1	performance					607:617	the performance	603:617	the performance of the copper oxide nanoparticle (CuONP) composite nanogel	603:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	8	75	theme	@	1206:1206	arg1	CTAC					1213:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	0	76	theme	pv	121:122	arg1	management					85:94	management	85:94	management of Pseudomonas synringae pv	85:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	7	77	theme	@	899:899	arg1	CTAC					906:909	PDA-CuONP@ALGNP@CTAC	890:909	PDA-CuONP@ALGNP@CTAC	890:909	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	77	theme	@	899:899	arg1	PDA					885:887	PDA	885:887	PDA (PDA-CuONP@ALGNP@CTAC)	885:910	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	9	78	theme	CuONP	1390:1394	arg1	nanogel					1406:1412	CuONP composite nanogel	1390:1412	CuONP composite nanogel	1390:1412	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	8	79	theme	@	1212:1212	arg1	CTAC					1213:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC	1193:1216	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	5	80	theme	reductant	590:598	arg1	effects					575:581	the effects	571:581	the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel	571:676	Therefore, we fabricate a new nanogel with high disease control and anti-erosion ability and study the effects of the reductant on the performance of the copper oxide nanoparticle (CuONP) composite nanogel.					
36414610	7	81	theme	sodium	1075:1080	arg1	borohydride					1082:1092	sodium borohydride	1075:1092	sodium borohydride	1075:1092	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	8	82	theme	high	1224:1227	arg1	ability					1242:1248	a high anti-erosion ability	1222:1248	a high anti-erosion ability	1222:1248	The PDA-CuONP@ALGNP@CTAC had a high anti-erosion ability and could remain adhered to the leaf surface even after five rain event simulations.					
36414610	9	83	theme	Cu2+	1433:1436	arg1	rate					1448:1451	the Cu2+ releasing rate	1429:1451	the Cu2+ releasing rate	1429:1451	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	0	84	theme	nanoparticle-alginate	40:60	arg1	nanogels					72:79	CuO nanoparticle-alginate composite nanogels	36:79	CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv	36:122	Fabrication of polydopamine reduced CuO nanoparticle-alginate composite nanogels for management of Pseudomonas synringae pv.					
36414610	7	85	theme	plant	1035:1039	arg1	promotion					1048:1056	plant growth promotion	1035:1056	plant growth promotion	1035:1056	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	6	86	theme	copper	801:806	arg1	ion					808:810	the copper ion	797:810	the copper ion (Cu2+ ) releasing rate in this work	797:846	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	6	86	theme	copper	801:806	arg1	Cu2+					813:816	Cu2+	813:816	Cu2+	813:816	RESULTS Polydopamine (PDA) is a polycation for both in situ reduction of CuONP in alginate nanogels and for adjusting the copper ion (Cu2+ ) releasing rate in this work.					
36414610	11	87	contain	has	1665:1667	arg2	potential					1676:1684	a high potential	1669:1684	a high potential for wildfire disease control	1669:1713	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	11	87	contain	has	1665:1667	arg1	nanogel					1657:1663	This new composite nanogel	1638:1663	This new composite nanogel	1638:1663	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36414610	7	88	theme	commercial	1149:1158	arg1	copper					1185:1190	thiodiazole copper	1173:1190	thiodiazole copper	1173:1190	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	88	theme	commercial	1149:1158	arg1	bactericide					1160:1170	the commercial bactericide	1145:1170	the commercial bactericide	1145:1170	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	2	89	dep	BACKGROUND	144:153	arg1	hinder					201:206	hinder	201:206	can seriously hinder plants	187:213	BACKGROUND The wildfire disease on tobacco can seriously hinder plants.					
36414610	9	90	theme	improved	1467:1474	arg1	management					1484:1493	improved disease management	1467:1493	improved disease management	1467:1493	CONCLUSION The addition of polycations (like PDA) into CuONP composite nanogel could increase the Cu2+ releasing rate, resulting in improved disease management when compared to SBH-CuONP@ALGNP@CTAC or thiodiazole copper.					
36414610	7	91	dep	-fabricated	1099:1109	arg1	borohydride					1082:1092	sodium borohydride	1075:1092	sodium borohydride	1075:1092	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	7	92	theme	higher	918:923	arg1	Cu2+					925:928	a higher Cu2+	916:928	a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper	916:1190	The composite nanogel fabricated by PDA (PDA-CuONP@ALGNP@CTAC) had a higher Cu2+ releasing rate, damaging the pathogen membrane more efficiently, allowing for better disease control and plant growth promotion when compared to sodium borohydride (SBH)-fabricated nanogel (SBH-CuONP@ALGNP@CTAC) or the commercial bactericide, thiodiazole copper.					
36414610	11	93	theme	wildfire	1690:1697	arg1	control					1707:1713	wildfire disease control	1690:1713	wildfire disease control	1690:1713	This new composite nanogel has a high potential for wildfire disease control, improving agricultural production.					
36111238	5	0	dep	2	793:793	arg1	Investigation					809:821	Phylogenetic Investigation	796:821	Phylogenetic Investigation of Communities by Reconstruction of Unobserved States	796:875	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	9	1	theme	active	1643:1648	arg1	disease					1650:1656	active disease	1643:1656	active disease	1643:1656	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	12	2	theme	substances	2002:2011	arg1	metabolism					1983:1992	the metabolism	1979:1992	the metabolism of some substances, such as methane, lipopolysaccharide, geraniol, and ansamycins,	1979:2075	Functional predictions indicated that gene functions involving the metabolism of some substances, such as methane, lipopolysaccharide, geraniol, and ansamycins, were significantly different among the three groups.					
36111238	14	3	theme	bacteria	2388:2395	arg1	species					2366:2372	different species	2356:2372	different species of intestinal bacteria	2356:2395	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	2	4	dep	Methods	302:308	arg1	enrolled					351:358	enrolled	351:358	enrolled into our study	351:373	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	2	4	dep	Methods	302:308	arg1	collected					380:388	collected	380:388	collected stool samples from, patients with active UC or in remission and healthy control subjects	380:477	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	12	5	theme	gene	1954:1957	arg1	functions					1959:1967	gene functions	1954:1967	gene functions involving the metabolism of some substances, such as methane, lipopolysaccharide, geraniol, and ansamycins,	1954:2075	Functional predictions indicated that gene functions involving the metabolism of some substances, such as methane, lipopolysaccharide, geraniol, and ansamycins, were significantly different among the three groups.					
36111238	7	6	theme	flora	1091:1095	arg1	compositions					1097:1108	the intestinal flora compositions	1076:1108	the intestinal flora compositions among the three groups	1076:1131	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	14	7	theme	different	2356:2364	arg1	species					2366:2372	different species	2356:2372	different species of intestinal bacteria	2356:2395	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	5	8	theme	Unobserved	859:868	arg1	States					870:875	Unobserved States	859:875	Unobserved States	859:875	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	15	9	theme	intestinal	2512:2521	arg1	microenvironment					2534:2549	the intestinal microbiota microenvironment	2508:2549	the intestinal microbiota microenvironment	2508:2549	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	4	10	theme	V3-V4	666:670	arg1	region					672:677	the 16S rRNA V3-V4 region	653:677	the 16S rRNA V3-V4 region	653:677	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	4	11	theme	microbiota	610:619	arg1	composition					580:590	The composition	576:590	The composition of the intestinal microbiota	576:619	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	3	12	theme	histological	553:564	arg1	findings					566:573	clinical, endoscopic, radiological, and histological findings	513:573	clinical, endoscopic, radiological, and histological findings	513:573	The diagnosis of UC was based on clinical, endoscopic, radiological, and histological findings.					
36111238	2	13	with	patients	410:417	arg1	UC					431:432	active UC	424:432	active UC	424:432	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	5	14	theme	Communities	826:836	arg1	Investigation					809:821	Phylogenetic Investigation	796:821	Phylogenetic Investigation of Communities by Reconstruction of Unobserved States	796:875	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	8	15	theme	UC	1452:1453	arg1	patients					1455:1462	UC patients	1452:1462	UC patients with active disease than in the healthy control group	1452:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	4	16	theme	region	672:677	arg1	sequencing					639:648	sequencing	639:648	sequencing of the 16S rRNA V3-V4 region	639:677	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	7	17	theme	diversity	1025:1033	arg1	analysis					1035:1042	Beta diversity analysis	1020:1042	Beta diversity analysis	1020:1042	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	1	18	theme	intestinal	137:146	arg1	microbiota					148:157	the intestinal microbiota	133:157	the intestinal microbiota	133:157	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	6	19	theme	healthy	994:1000	arg1	subjects					1010:1017	healthy control subjects	994:1017	healthy control subjects	994:1017	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	7	20	theme	active	1218:1223	arg1	disease					1225:1231	active disease	1218:1231	active disease	1218:1231	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	2	21	theme	healthy	454:460	arg1	subjects					470:477	healthy control subjects	454:477	healthy control subjects	454:477	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	4	22	theme	rRNA	661:664	arg1	region					672:677	the 16S rRNA V3-V4 region	653:677	the 16S rRNA V3-V4 region	653:677	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	1	23	theme	colitis	173:179	arg1	patients					186:193	ulcerative colitis (UC) patients	162:193	ulcerative colitis (UC) patients	162:193	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	6	24	theme	UC	974:975	arg1	patients					977:984	UC patients	974:984	UC patients	974:984	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	8	25	theme	healthy	1496:1502	arg1	group					1512:1516	the healthy control group	1492:1516	the healthy control group	1492:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	26	theme	Patescibacteria	1324:1338	arg1	abundances					1291:1300	the relative abundances	1278:1300	the relative abundances of Proteobacteria and Patescibacteria	1278:1338	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	26	theme	Patescibacteria	1324:1338	arg1	higher					1359:1364	higher	1359:1364	higher	1359:1364	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	14	27	theme	intestinal	2300:2309	arg1	bacteria					2311:2318	intestinal bacteria	2300:2318	intestinal bacteria	2300:2318	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	8	28	from	disease	1476:1482	arg1	group					1512:1516	the healthy control group	1492:1516	the healthy control group	1492:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	12	29	theme	Functional	1916:1925	arg1	predictions					1927:1937	Functional predictions	1916:1937	Functional predictions	1916:1937	Functional predictions indicated that gene functions involving the metabolism of some substances, such as methane, lipopolysaccharide, geraniol, and ansamycins, were significantly different among the three groups.					
36111238	2	30	with	subjects	470:477	arg1	UC					431:432	active UC	424:432	active UC	424:432	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	9	31	theme	potential	1536:1544	arg1	pathogens					1546:1554	potential pathogens	1536:1554	potential pathogens	1536:1554	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	14	32	dep	describes	2253:2261	arg1	whereas					2321:2327	whereas	2321:2327	whereas	2321:2327	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	10	33	theme	Linear	1659:1664	arg1	analysis					1679:1686	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	7	34	theme	alpha	1177:1181	arg1	diversity					1183:1191	alpha diversity	1177:1191	alpha diversity	1177:1191	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	15	35	theme	bacterial	2408:2416	arg1	biomarkers					2440:2449	biomarkers	2440:2449	biomarkers	2440:2449	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	15	35	theme	bacterial	2408:2416	arg1	taxa					2418:2421	Different bacterial taxa	2398:2421	Different bacterial taxa	2398:2421	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	0	36	theme	intestinal	39:48	arg1	microbiota					50:59	intestinal microbiota	39:59	intestinal microbiota	39:59	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	10	37	from	level	1799:1803	arg1	biomarkers					1775:1784	26 biomarkers	1772:1784	26 biomarkers at the genus level	1772:1803	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	14	38	from	rich	2282:2285	arg1	number					2290:2295	number	2290:2295	number of intestinal bacteria	2290:2318	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	2	39	theme	active	424:429	arg1	UC					431:432	active UC	424:432	active UC	424:432	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	7	40	from	difference	1163:1172	arg1	diversity					1183:1191	alpha diversity	1177:1191	alpha diversity	1177:1191	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	6	41	from	patients	977:984	arg1	flora					925:929	the intestinal flora	910:929	the intestinal flora	910:929	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	6	41	from	patients	977:984	arg1	rich					954:957	rich	954:957	rich	954:957	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	0	42	theme	colitis	75:81	arg1	patients					83:90	ulcerative colitis patients	64:90	ulcerative colitis patients	64:90	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	5	43	theme	PICRUSt	785:791	arg1	software					878:885	PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software	785:885	PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software	785:885	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	1	44	from	composition	118:128	arg1	patients					186:193	ulcerative colitis (UC) patients	162:193	ulcerative colitis (UC) patients	162:193	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	14	45	from	number	2290:2295	arg1	rich					2282:2285	rich	2282:2285	rich	2282:2285	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	9	46	located	detected	1614:1621	arg2	levels					1526:1531	Higher levels	1519:1531	Higher levels of potential pathogens	1519:1554	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	9	46	located	detected	1614:1621	arg2	levels					1566:1571	lower levels	1560:1571	lower levels of butyrate-producing bacteria	1560:1602	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	9	46	located	detected	1614:1621	arg1	patients					1629:1636	UC patients	1626:1636	UC patients with active disease	1626:1656	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	0	47	theme	diverse	16:22	arg1	differences					24:34	diverse differences	16:34	diverse differences	16:34	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	9	48	theme	butyrate-producing	1576:1593	arg1	bacteria					1595:1602	butyrate-producing bacteria	1576:1602	butyrate-producing bacteria	1576:1602	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	1	49	theme	microbiota	148:157	arg1	composition					118:128	the composition	114:128	the composition of the intestinal microbiota in ulcerative colitis (UC) patients	114:193	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	10	50	dep	analysis	1679:1686	arg1	LefSe					1701:1705	LefSe	1701:1705	LefSe	1701:1705	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	10	50	dep	analysis	1679:1686	arg1	Size					1695:1698	Effect Size	1688:1698	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	2	51	theme	stool	390:394	arg1	samples					396:402	stool samples	390:402	stool samples	390:402	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	5	52	theme	microbiota	754:763	arg1	composition					724:734	The functional composition	709:734	The functional composition of the intestinal microbiota	709:763	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	0	53	theme	ulcerative	64:73	arg1	patients					83:90	ulcerative colitis patients	64:90	ulcerative colitis patients	64:90	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	8	54	theme	Desulfobacterota	1398:1413	arg1	abundances					1384:1393	the relative abundances	1371:1393	the relative abundances of Desulfobacterota and Verrucomicrobiota	1371:1435	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	54	theme	Desulfobacterota	1398:1413	arg1	lower					1442:1446	lower	1442:1446	lower	1442:1446	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	55	with	patients	1455:1462	arg1	disease					1476:1482	active disease	1469:1482	active disease than in the healthy control group	1469:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	0	56	theme	microbiota	50:59	arg1	Composition					0:10	Composition	0:10	Composition	0:10	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	0	56	theme	microbiota	50:59	arg1	differences					24:34	diverse differences	16:34	diverse differences	16:34	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	2	57	from	patients	410:417	arg1	remission					440:448	remission	440:448	remission	440:448	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	1	58	with	patients	249:256	arg1	disease					270:276	active disease	263:276	active disease	263:276	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	8	59	theme	Verrucomicrobiota	1419:1435	arg1	abundances					1384:1393	the relative abundances	1371:1393	the relative abundances of Desulfobacterota and Verrucomicrobiota	1371:1435	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	59	theme	Verrucomicrobiota	1419:1435	arg1	lower					1442:1446	lower	1442:1446	lower	1442:1446	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	11	60	theme	network	1819:1825	arg1	analysis					1827:1834	network analysis	1819:1834	network analysis	1819:1834	In addition, network analysis showed that there was a positive correlation between Roseburia and Lachnospira.					
36111238	9	61	theme	UC	1626:1627	arg1	patients					1629:1636	UC patients	1626:1636	UC patients with active disease	1626:1656	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	9	62	with	patients	1629:1636	arg1	disease					1650:1656	active disease	1643:1656	active disease	1643:1656	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	13	63	theme	microbiota	2186:2195	arg1	Conclusion					2130:2139	Conclusion The richness and diversity	2130:2166	Conclusion The richness and diversity of the intestinal microbiota	2130:2195	Conclusion The richness and diversity of the intestinal microbiota differed significantly among the three groups.					
36111238	6	64	dep	Results	888:894	arg1	found					899:903	found	899:903	found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects	899:1017	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	14	65	theme	species	2366:2372	arg1	diversity					2329:2337	diversity	2329:2337	diversity	2329:2337	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	14	65	theme	species	2366:2372	arg1	number					2346:2351	the number	2342:2351	the number of different species of intestinal bacteria	2342:2395	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	1	66	theme	active	263:268	arg1	disease					270:276	active disease	263:276	active disease	263:276	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	8	67	theme	Proteobacteria	1305:1318	arg1	abundances					1291:1300	the relative abundances	1278:1300	the relative abundances of Proteobacteria and Patescibacteria	1278:1338	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	67	theme	Proteobacteria	1305:1318	arg1	higher					1359:1364	higher	1359:1364	higher	1359:1364	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	7	68	from	differences	1061:1071	arg1	compositions					1097:1108	the intestinal flora compositions	1076:1108	the intestinal flora compositions among the three groups	1076:1131	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	7	69	theme	intestinal	1080:1089	arg1	compositions					1097:1108	the intestinal flora compositions	1076:1108	the intestinal flora compositions among the three groups	1076:1131	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	14	70	theme	intestinal	2377:2386	arg1	bacteria					2388:2395	intestinal bacteria	2377:2395	intestinal bacteria	2377:2395	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	3	71	theme	UC	497:498	arg1	diagnosis					484:492	The diagnosis	480:492	The diagnosis of UC	480:498	The diagnosis of UC was based on clinical, endoscopic, radiological, and histological findings.					
36111238	6	72	from	subjects	1010:1017	arg1	flora					925:929	the intestinal flora	910:929	the intestinal flora	910:929	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	6	72	from	subjects	1010:1017	arg1	rich					954:957	rich	954:957	rich	954:957	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	3	73	theme	endoscopic	523:532	arg1	findings					566:573	clinical, endoscopic, radiological, and histological findings	513:573	clinical, endoscopic, radiological, and histological findings	513:573	The diagnosis of UC was based on clinical, endoscopic, radiological, and histological findings.					
36111238	7	74	theme	notable	1053:1059	arg1	differences					1061:1071	notable differences	1053:1071	notable differences in the intestinal flora compositions among the three groups	1053:1131	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	3	75	theme	clinical	513:520	arg1	findings					566:573	clinical, endoscopic, radiological, and histological findings	513:573	clinical, endoscopic, radiological, and histological findings	513:573	The diagnosis of UC was based on clinical, endoscopic, radiological, and histological findings.					
36111238	5	76	theme	Phylogenetic	796:807	arg1	Investigation					809:821	Phylogenetic Investigation	796:821	Phylogenetic Investigation of Communities by Reconstruction of Unobserved States	796:875	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	15	77	theme	Different	2398:2406	arg1	biomarkers					2440:2449	biomarkers	2440:2449	biomarkers	2440:2449	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	15	77	theme	Different	2398:2406	arg1	taxa					2418:2421	Different bacterial taxa	2398:2421	Different bacterial taxa	2398:2421	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	9	78	theme	Higher	1519:1524	arg1	levels					1526:1531	Higher levels	1519:1531	Higher levels of potential pathogens	1519:1554	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	2	79	from	subjects	470:477	arg1	remission					440:448	remission	440:448	remission	440:448	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	4	80	theme	intestinal	599:608	arg1	microbiota					610:619	the intestinal microbiota	595:619	the intestinal microbiota	595:619	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	7	81	theme	Beta	1020:1023	arg1	analysis					1035:1042	Beta diversity analysis	1020:1042	Beta diversity analysis	1020:1042	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	3	82	theme	radiological	535:546	arg1	findings					566:573	clinical, endoscopic, radiological, and histological findings	513:573	clinical, endoscopic, radiological, and histological findings	513:573	The diagnosis of UC was based on clinical, endoscopic, radiological, and histological findings.					
36111238	1	83	from	differences	211:221	arg1	microbiota					230:239	the microbiota	226:239	the microbiota	226:239	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	0	84	from	Composition	0:10	arg1	patients					83:90	ulcerative colitis patients	64:90	ulcerative colitis patients	64:90	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	6	85	theme	intestinal	914:923	arg1	flora					925:929	the intestinal flora	910:929	the intestinal flora	910:929	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	6	85	theme	intestinal	914:923	arg1	rich					954:957	rich	954:957	rich	954:957	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	8	86	theme	active	1469:1474	arg1	disease					1476:1482	active disease	1469:1482	active disease than in the healthy control group	1469:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	87	theme	phylum	1264:1269	arg1	level					1271:1275	the phylum level	1260:1275	the phylum level	1260:1275	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	15	88	theme	relationship	2487:2498	arg1	understanding					2466:2478	our understanding	2462:2478	our understanding of the relationship between the intestinal microbiota microenvironment	2462:2549	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	15	88	theme	relationship	2487:2498	arg1	UC					2555:2556	UC	2555:2556	UC	2555:2556	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	6	89	theme	control	1002:1008	arg1	subjects					1010:1017	healthy control subjects	994:1017	healthy control subjects	994:1017	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	13	90	dep	richness	2145:2152	arg1	The					2141:2143	The	2141:2143	The	2141:2143	Conclusion The richness and diversity of the intestinal microbiota differed significantly among the three groups.					
36111238	7	91	with	patients	1204:1211	arg1	disease					1225:1231	active disease	1218:1231	active disease	1218:1231	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	15	92	used	used	2432:2435	arg2	biomarkers					2440:2449	biomarkers	2440:2449	biomarkers	2440:2449	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	15	92	used	used	2432:2435	arg2	taxa					2418:2421	Different bacterial taxa	2398:2421	Different bacterial taxa	2398:2421	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	5	93	theme	functional	713:722	arg1	composition					724:734	The functional composition	709:734	The functional composition of the intestinal microbiota	709:763	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	5	94	theme	States	870:875	arg1	Reconstruction					841:854	Reconstruction	841:854	Reconstruction of Unobserved States	841:875	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	2	95	theme	control	462:468	arg1	subjects					470:477	healthy control subjects	454:477	healthy control subjects	454:477	Methods Between September 2020 and June 2021, we enrolled into our study, and collected stool samples from, patients with active UC or in remission and healthy control subjects.					
36111238	0	96	from	differences	24:34	arg1	patients					83:90	ulcerative colitis patients	64:90	ulcerative colitis patients	64:90	Composition and diverse differences of intestinal microbiota in ulcerative colitis patients.					
36111238	8	97	theme	relative	1282:1289	arg1	abundances					1291:1300	the relative abundances	1278:1300	the relative abundances of Proteobacteria and Patescibacteria	1278:1338	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	97	theme	relative	1282:1289	arg1	higher					1359:1364	higher	1359:1364	higher	1359:1364	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	7	98	theme	UC	1201:1202	arg1	patients					1204:1211	UC patients	1201:1211	UC patients with active disease	1201:1231	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	1	99	theme	ulcerative	162:171	arg1	UC					182:183	UC	182:183	UC	182:183	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	1	99	theme	ulcerative	162:171	arg1	colitis					173:179	ulcerative colitis	162:179	ulcerative colitis (UC) patients	162:193	Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission.					
36111238	8	100	theme	control	1504:1510	arg1	group					1512:1516	the healthy control group	1492:1516	the healthy control group	1492:1516	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	4	101	theme	16S	657:659	arg1	region					672:677	the 16S rRNA V3-V4 region	653:677	the 16S rRNA V3-V4 region	653:677	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	14	102	theme	bacteria	2311:2318	arg1	number					2290:2295	number	2290:2295	number of intestinal bacteria	2290:2318	Richness describes the state of being rich in number of intestinal bacteria, whereas diversity is the number of different species of intestinal bacteria.					
36111238	9	103	theme	pathogens	1546:1554	arg1	levels					1566:1571	lower levels	1560:1571	lower levels of butyrate-producing bacteria	1560:1602	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	9	103	theme	pathogens	1546:1554	arg1	levels					1526:1531	Higher levels	1519:1531	Higher levels of potential pathogens	1519:1554	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	7	104	theme	statistical	1151:1161	arg1	difference					1163:1172	no statistical difference	1148:1172	no statistical difference in alpha diversity between UC patients with active disease and those in remission	1148:1254	Beta diversity analysis revealed notable differences in the intestinal flora compositions among the three groups, but there was no statistical difference in alpha diversity between UC patients with active disease and those in remission.					
36111238	9	105	theme	lower	1560:1564	arg1	levels					1566:1571	lower levels	1560:1571	lower levels of butyrate-producing bacteria	1560:1602	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	4	106	theme	bioinformatic	686:698	arg1	methods					700:706	bioinformatic methods	686:706	bioinformatic methods	686:706	The composition of the intestinal microbiota was determined by sequencing of the 16S rRNA V3-V4 region and by bioinformatic methods.					
36111238	5	107	theme	2	793:793	arg1	software					878:885	PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software	785:885	PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software	785:885	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	15	108	theme	microbiota	2523:2532	arg1	microenvironment					2534:2549	the intestinal microbiota microenvironment	2508:2549	the intestinal microbiota microenvironment	2508:2549	Different bacterial taxa could be used as biomarkers, expanding our understanding of the relationship between the intestinal microbiota microenvironment and UC in the future.					
36111238	10	109	theme	Effect	1688:1693	arg1	LefSe					1701:1705	LefSe	1701:1705	LefSe	1701:1705	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	10	109	theme	Effect	1688:1693	arg1	Size					1695:1698	Effect Size	1688:1698	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	5	110	theme	intestinal	743:752	arg1	microbiota					754:763	the intestinal microbiota	739:763	the intestinal microbiota	739:763	The functional composition of the intestinal microbiota was predicted using PICRUSt 2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) software.					
36111238	9	111	theme	bacteria	1595:1602	arg1	levels					1566:1571	lower levels	1560:1571	lower levels of butyrate-producing bacteria	1560:1602	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	9	111	theme	bacteria	1595:1602	arg1	levels					1526:1531	Higher levels	1519:1531	Higher levels of potential pathogens	1519:1554	Higher levels of potential pathogens and lower levels of butyrate-producing bacteria were also detected in UC patients with active disease.					
36111238	6	112	from	rich	954:957	arg1	subjects					1010:1017	healthy control subjects	994:1017	healthy control subjects	994:1017	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	6	112	from	rich	954:957	arg1	patients					977:984	UC patients	974:984	UC patients	974:984	Results We found that the intestinal flora was significantly less rich and diverse in UC patients than in healthy control subjects.					
36111238	8	113	theme	relative	1375:1382	arg1	abundances					1384:1393	the relative abundances	1371:1393	the relative abundances of Desulfobacterota and Verrucomicrobiota	1371:1435	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	8	113	theme	relative	1375:1382	arg1	lower					1442:1446	lower	1442:1446	lower	1442:1446	At the phylum level, the relative abundances of Proteobacteria and Patescibacteria were significantly higher, and the relative abundances of Desulfobacterota and Verrucomicrobiota were lower, in UC patients with active disease than in the healthy control group.					
36111238	10	114	theme	discriminant	1666:1677	arg1	analysis					1679:1686	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe)	1659:1706	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	10	115	theme	genus	1793:1797	arg1	level					1799:1803	the genus level	1789:1803	the genus level	1789:1803	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	13	116	dep	Conclusion	2130:2139	arg1	diversity					2158:2166	diversity	2158:2166	diversity	2158:2166	Conclusion The richness and diversity of the intestinal microbiota differed significantly among the three groups.					
36111238	13	116	dep	Conclusion	2130:2139	arg1	richness					2145:2152	richness	2145:2152	richness	2145:2152	Conclusion The richness and diversity of the intestinal microbiota differed significantly among the three groups.					
36111238	11	117	theme	positive	1860:1867	arg1	correlation					1869:1879	a positive correlation	1858:1879	a positive correlation between Roseburia and Lachnospira	1858:1913	In addition, network analysis showed that there was a positive correlation between Roseburia and Lachnospira.					
36111238	13	118	theme	intestinal	2175:2184	arg1	microbiota					2186:2195	the intestinal microbiota	2171:2195	the intestinal microbiota	2171:2195	Conclusion The richness and diversity of the intestinal microbiota differed significantly among the three groups.					
36111238	10	119	theme	bacterial	1725:1733	arg1	biomarkers					1755:1764	biomarkers	1755:1764	biomarkers	1755:1764	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36111238	10	119	theme	bacterial	1725:1733	arg1	taxa					1735:1738	71 bacterial taxa	1722:1738	71 bacterial taxa	1722:1738	Linear discriminant analysis Effect Size (LefSe) revealed that 71 bacterial taxa could serve as biomarkers, with 26 biomarkers at the genus level.					
36907133	1	0	contain	have	154:157	arg2	potential					165:173	great potential	159:173	great potential	159:173	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	1	0	contain	have	154:157	arg1	coatings					113:120	Biocompatible coatings	99:120	Biocompatible coatings that can protect metal implants	99:152	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	8	1	theme	simulated	1117:1125	arg1	fluids					1132:1137	simulated body fluids	1117:1137	simulated body fluids	1117:1137	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	1	2	theme	tissue	178:183	arg1	engineering					185:195	tissue engineering	178:195	tissue engineering	178:195	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	8	3	theme	coating	1194:1200	arg1	surface					1202:1208	the coating surface	1190:1208	the coating surface	1190:1208	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	9	4	theme	implant	1304:1310	arg1	anticorrosion					1312:1324	implant anticorrosion	1304:1324	implant anticorrosion	1304:1324	This study contributes to furthering the practical application of chitosan-based coatings in implant anticorrosion.					
36907133	7	5	theme	simulated	954:962	arg1	drops					975:979	the simulated body fluid drops	950:979	the simulated body fluid drops to 0.1 mg/L	950:991	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	3	6	theme	mechanical	433:442	arg1	0.76 MPa					454:461	0.76 MPa	454:461	0.76 MPa	454:461	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	3	6	theme	mechanical	433:442	arg1	strength					444:451	mechanical strength	433:451	mechanical strength (0.76 MPa)	433:462	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	6	7	theme	5.361 × 10-3	869:880	arg1	mm/yr					882:886	5.361 × 10-3 mm/yr	869:886	5.361 × 10-3 mm/yr	869:886	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	9	8	theme	coatings	1292:1299	arg1	application					1262:1272	the practical application	1248:1272	the practical application of chitosan-based coatings in implant anticorrosion	1248:1324	This study contributes to furthering the practical application of chitosan-based coatings in implant anticorrosion.					
36907133	7	9	theme	body	964:967	arg1	drops					975:979	the simulated body fluid drops	950:979	the simulated body fluid drops to 0.1 mg/L	950:991	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	8	10	theme	body	1127:1130	arg1	fluids					1132:1137	simulated body fluids	1117:1137	simulated body fluids	1117:1137	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	7	11	theme	coating	1031:1037	arg1	protection					1003:1012	the protection	999:1012	the protection of the composite coating	999:1037	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	2	12	with	coatings	237:244	arg1	wettability					286:296	hydrophobic-hydrophilic asymmetric wettability	251:296	hydrophobic-hydrophilic asymmetric wettability	251:296	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	8	13	theme	composite	1057:1065	arg1	coating					1067:1073	the composite coating	1053:1073	the composite coating	1053:1073	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	2	14	theme	in	333:334	arg1	electrodeposition					341:357	one-step in situ electrodeposition	324:357	one-step in situ electrodeposition	324:357	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	5	15	theme	compact	712:718	arg1	structure					729:737	compact internal structure	712:737	compact internal structure	712:737	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	8	16	theme	efficient	1083:1091	arg1	enrichment					1101:1110	efficient calcium enrichment	1083:1110	efficient calcium enrichment from simulated body fluids	1083:1137	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	1	17	theme	Biocompatible	99:111	arg1	coatings					113:120	Biocompatible coatings	99:120	Biocompatible coatings that can protect metal implants	99:152	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	6	18	theme	corrosion	789:797	arg1	rate					799:802	its corrosion rate	785:802	its corrosion rate	785:802	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	9	19	from	application	1262:1272	arg1	anticorrosion					1312:1324	implant anticorrosion	1304:1324	implant anticorrosion	1304:1324	This study contributes to furthering the practical application of chitosan-based coatings in implant anticorrosion.					
36907133	0	20	theme	MWCNT/chitosan	11:24	arg1	composite					26:34	Biological MWCNT/chitosan composite	0:34	Biological MWCNT/chitosan composite	0:34	Biological MWCNT/chitosan composite coating with outstanding anti-corrosion property for implants.					
36907133	5	21	theme	internal	720:727	arg1	structure					729:737	compact internal structure	712:737	compact internal structure	712:737	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	5	22	theme	lower	661:665	arg1	rate					677:680	a lower corrosion rate	659:680	a lower corrosion rate due to its hydrophobicity and compact internal structure	659:737	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	3	23	theme	internal	493:500	arg1	structure					502:510	the compact internal structure	481:510	the compact internal structure	481:510	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	0	24	theme	Biological	0:9	arg1	composite					26:34	Biological MWCNT/chitosan composite	0:34	Biological MWCNT/chitosan composite	0:34	Biological MWCNT/chitosan composite coating with outstanding anti-corrosion property for implants.					
36907133	8	25	from	fluids	1132:1137	arg1	enrichment					1101:1110	efficient calcium enrichment	1083:1110	efficient calcium enrichment from simulated body fluids	1083:1137	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	5	26	theme	corrosion	667:675	arg1	rate					677:680	a lower corrosion rate	659:680	a lower corrosion rate due to its hydrophobicity and compact internal structure	659:737	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	8	27	theme	bioapatite	1169:1178	arg1	layers					1180:1185	bioapatite layers	1169:1185	bioapatite layers	1169:1185	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	8	28	theme	calcium	1093:1099	arg1	enrichment					1101:1110	efficient calcium enrichment	1083:1110	efficient calcium enrichment from simulated body fluids	1083:1137	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	7	29	theme	316 L	923:927	arg1	steel					939:943	316 L stainless steel	923:943	316 L stainless steel	923:943	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	6	30	theme	stainless	768:776	arg1	steel					778:782	exposed 316 L stainless steel	754:782	exposed 316 L stainless steel	754:782	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	6	31	from	mm/yr	860:864	arg1	orders					822:827	two orders	818:827	two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr	818:886	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	6	32	theme	316 L	762:766	arg1	steel					778:782	exposed 316 L stainless steel	754:782	exposed 316 L stainless steel	754:782	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	3	33	theme	compact	485:491	arg1	structure					502:510	the compact internal structure	481:510	the compact internal structure	481:510	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	4	34	theme	charges	600:606	arg1	amounts					577:583	the amounts	573:583	the amounts of transferred charges	573:606	The thickness of the coating can be controlled precisely by the amounts of transferred charges.					
36907133	4	34	theme	charges	600:606	arg1	charges					600:606	transferred charges	588:606	transferred charges	588:606	The thickness of the coating can be controlled precisely by the amounts of transferred charges.					
36907133	8	35	theme	layers	1180:1185	arg1	formation					1156:1164	the formation	1152:1164	the formation of bioapatite layers on the coating surface	1152:1208	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	4	36	theme	coating	534:540	arg1	thickness					517:525	The thickness	513:525	The thickness of the coating	513:540	The thickness of the coating can be controlled precisely by the amounts of transferred charges.					
36907133	2	37	theme	asymmetric	275:284	arg1	wettability					286:296	hydrophobic-hydrophilic asymmetric wettability	251:296	hydrophobic-hydrophilic asymmetric wettability	251:296	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	5	38	theme	MWCNT/chitosan	613:626	arg1	coating					638:644	The MWCNT/chitosan composite coating	609:644	The MWCNT/chitosan composite coating	609:644	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	4	39	theme	transferred	588:598	arg1	charges					600:606	transferred charges	588:606	transferred charges	588:606	The thickness of the coating can be controlled precisely by the amounts of transferred charges.					
36907133	3	40	theme	resultant	364:372	arg1	coating					384:390	The resultant composite coating	360:390	The resultant composite coating	360:390	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	2	41	theme	hydrophobic-hydrophilic	251:273	arg1	wettability					286:296	hydrophobic-hydrophilic asymmetric wettability	251:296	hydrophobic-hydrophilic asymmetric wettability	251:296	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	5	42	theme	composite	628:636	arg1	coating					638:644	The MWCNT/chitosan composite coating	609:644	The MWCNT/chitosan composite coating	609:644	The MWCNT/chitosan composite coating demonstrates a lower corrosion rate due to its hydrophobicity and compact internal structure.					
36907133	1	43	theme	metal	139:143	arg1	implants					145:152	metal implants	139:152	metal implants	139:152	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	0	44	theme	anti-corrosion	61:74	arg1	property					76:83	anti-corrosion property	61:83	anti-corrosion property for implants	61:96	Biological MWCNT/chitosan composite coating with outstanding anti-corrosion property for implants.					
36907133	7	45	theme	composite	1021:1029	arg1	coating					1031:1037	the composite coating	1017:1037	the composite coating	1017:1037	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	3	46	theme	composite	374:382	arg1	coating					384:390	The resultant composite coating	360:390	The resultant composite coating	360:390	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	6	47	theme	magnitude	832:840	arg1	orders					822:827	two orders	818:827	two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr	818:886	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	6	48	theme	exposed	754:760	arg1	steel					778:782	exposed 316 L stainless steel	754:782	exposed 316 L stainless steel	754:782	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	8	49	from	formation	1156:1164	arg1	surface					1202:1208	the coating surface	1190:1208	the coating surface	1190:1208	In addition, the composite coating enables efficient calcium enrichment from simulated body fluids and promotes the formation of bioapatite layers on the coating surface.					
36907133	2	50	theme	composite	227:235	arg1	coatings					237:244	MWCNT/chitosan composite coatings	212:244	MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability	212:296	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	9	51	theme	chitosan-based	1277:1290	arg1	coatings					1292:1299	chitosan-based coatings	1277:1299	chitosan-based coatings	1277:1299	This study contributes to furthering the practical application of chitosan-based coatings in implant anticorrosion.					
36907133	2	52	theme	one-step	324:331	arg1	electrodeposition					341:357	one-step in situ electrodeposition	324:357	one-step in situ electrodeposition	324:357	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	2	53	theme	MWCNT/chitosan	212:225	arg1	coatings					237:244	MWCNT/chitosan composite coatings	212:244	MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability	212:296	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	6	54	theme	3.004 × 10-1	847:858	arg1	mm/yr					860:864	3.004 × 10-1 mm/yr	847:864	3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr	847:886	Compared with exposed 316 L stainless steel, its corrosion rate is reduced by two orders of magnitude from 3.004 × 10-1 mm/yr to 5.361 × 10-3 mm/yr.					
36907133	1	55	theme	great	159:163	arg1	potential					165:173	great potential	159:173	great potential	159:173	Biocompatible coatings that can protect metal implants have great potential in tissue engineering.					
36907133	7	56	theme	iron	904:907	arg1	content					893:899	The content	889:899	The content of iron	889:907	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	7	57	theme	stainless	929:937	arg1	steel					939:943	316 L stainless steel	923:943	316 L stainless steel	923:943	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
36907133	3	58	theme	excellent	401:409	arg1	stability					419:427	excellent thermal stability	401:427	excellent thermal stability	401:427	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	2	59	dep	in	333:334	arg1	situ					336:339	situ	336:339	situ	336:339	In this work, MWCNT/chitosan composite coatings with hydrophobic-hydrophilic asymmetric wettability were facilely prepared by one-step in situ electrodeposition.					
36907133	3	60	theme	thermal	411:417	arg1	stability					419:427	excellent thermal stability	401:427	excellent thermal stability	401:427	The resultant composite coating exhibits excellent thermal stability and mechanical strength (0.76 MPa), benefiting from the compact internal structure.					
36907133	9	61	theme	practical	1252:1260	arg1	application					1262:1272	the practical application	1248:1272	the practical application of chitosan-based coatings in implant anticorrosion	1248:1324	This study contributes to furthering the practical application of chitosan-based coatings in implant anticorrosion.					
36907133	7	62	theme	fluid	969:973	arg1	drops					975:979	the simulated body fluid drops	950:979	the simulated body fluid drops to 0.1 mg/L	950:991	The content of iron released from 316 L stainless steel into the simulated body fluid drops to 0.1 mg/L under the protection of the composite coating.					
35195399	6	0	theme	hydrogels	1096:1104	arg1	character					1069:1077	the dynamic character	1057:1077	the dynamic character of the resulting hydrogels	1057:1104	Furthermore, we show that viscoelasticity and the dynamic character of the resulting hydrogels could be tuned by changing the composition, that is, the ratio between the two types of cross-links.					
35195399	6	0	theme	hydrogels	1096:1104	arg1	viscoelasticity					1037:1051	viscoelasticity	1037:1051	viscoelasticity	1037:1051	Furthermore, we show that viscoelasticity and the dynamic character of the resulting hydrogels could be tuned by changing the composition, that is, the ratio between the two types of cross-links.					
35195399	11	1	theme	viscoelastic	2263:2274	arg1	materials					2276:2284	novel smart and tunable viscoelastic materials	2239:2284	novel smart and tunable viscoelastic materials	2239:2284	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	7	2	theme	first	1360:1364	arg1	stages					1366:1371	the first stages	1356:1371	the first stages of gelation	1356:1383	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	8	3	theme	structural	1580:1589	arg1	stability					1591:1599	structural stability	1580:1599	structural stability	1580:1599	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	3	4	link	cross-linked	384:395	arg1	hydrogels					421:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	4	5	theme	acid	678:681	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	7	6	theme	gelation	1376:1383	arg1	stages					1366:1371	the first stages	1356:1371	the first stages of gelation	1356:1383	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	10	7	theme	hydrogels	2007:2015	arg1	presence					1991:1998	the presence	1987:1998	the presence of the hydrogels	1987:2015	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	4	8	theme	CS/HA	684:688	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	11	9	with	hydrogels	2151:2159	arg1	cross-links					2183:2193	dynamic covalent cross-links	2166:2193	dynamic covalent cross-links	2166:2193	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	9	10	from	results	1769:1775	arg1	constructs					1802:1811	osmotically stiffened constructs	1780:1811	osmotically stiffened constructs	1780:1811	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	9	11	theme	cartilage	1857:1865	arg1	tissue					1867:1872	cartilage tissue	1857:1872	cartilage tissue	1857:1872	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	6	12	theme	resulting	1086:1094	arg1	hydrogels					1096:1104	the resulting hydrogels	1082:1104	the resulting hydrogels	1082:1104	Furthermore, we show that viscoelasticity and the dynamic character of the resulting hydrogels could be tuned by changing the composition, that is, the ratio between the two types of cross-links.					
35195399	5	13	theme	Diels-Alder	839:849	arg1	adducts					851:857	Diels-Alder adducts	839:857	Diels-Alder adducts (between methylfuran and maleimide)	839:893	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	5	13	theme	Diels-Alder	839:849	arg1	cross-links					963:973	cross-links	963:973	cross-links	963:973	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	5	13	theme	Diels-Alder	839:849	arg1	bonds					909:913	hydrazone bonds	899:913	hydrazone bonds (between aldehyde and hydrazide)	899:946	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	11	14	theme	great	2200:2204	arg1	potential					2206:2214	great potential	2200:2214	great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine	2200:2367	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	4	15	theme	chondroitin	647:657	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	9	16	dep	capacity	1690:1697	arg1	ratio					1717:1721	maximum swelling ratio	1700:1721	maximum swelling ratio ranging from 6 to 12	1700:1742	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	7	17	theme	DN	1300:1301	arg1	injectable					1341:1350	injectable	1341:1350	injectable	1341:1350	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	17	theme	DN	1300:1301	arg1	hydrogel					1303:1310	the DN hydrogel	1296:1310	the DN hydrogel	1296:1310	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	17	theme	DN	1300:1301	arg1	processable					1322:1332	processable	1322:1332	processable	1322:1332	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	10	18	theme	products	2052:2059	arg1	effect					2026:2031	the effect	2022:2031	the effect of the degradation products on the macrophages	2022:2078	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	9	19	theme	swelling	1681:1688	arg1	capacity					1690:1697	a high swelling capacity	1674:1697	a high swelling capacity (maximum swelling ratio ranging from 6 to 12)	1674:1743	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	10	20	theme	safe	2095:2098	arg1	use					2100:2102	their safe use	2089:2102	their safe use for further translational applications	2089:2141	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	4	21	theme	-based	690:695	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	4	22	theme	hydrogels	700:708	arg1	fabrication					632:642	the fabrication	628:642	the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes	628:828	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	10	23	theme	stromal	1958:1964	arg1	viable					1977:1982	viable	1977:1982	viable	1977:1982	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	10	23	theme	stromal	1958:1964	arg1	cells					1966:1970	the mesenchymal stromal cells	1942:1970	the mesenchymal stromal cells	1942:1970	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	9	24	theme	swelling	1708:1715	arg1	ratio					1717:1721	maximum swelling ratio	1700:1721	maximum swelling ratio ranging from 6 to 12	1700:1742	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	10	25	theme	translational	2116:2128	arg1	applications					2130:2141	further translational applications	2108:2141	further translational applications	2108:2141	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	7	26	dep	nature	1235:1240	arg1	a					1220:1220	a	1220:1220	a	1220:1220	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	4	27	theme	dynamic	779:785	arg1	bonds					796:800	the dynamic covalent bonds	775:800	the dynamic covalent bonds of very different lifetimes	775:828	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	10	28	from	presence	1991:1998	arg1	viable					1977:1982	viable	1977:1982	viable	1977:1982	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	10	28	from	presence	1991:1998	arg1	cells					1966:1970	the mesenchymal stromal cells	1942:1970	the mesenchymal stromal cells	1942:1970	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	0	29	theme	Viscoelastic	0:11	arg1	Sulfate					25:31	Viscoelastic Chondroitin Sulfate	0:31	Viscoelastic Chondroitin Sulfate	0:31	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	6	30	theme	dynamic	1061:1067	arg1	character					1069:1077	the dynamic character	1057:1077	the dynamic character of the resulting hydrogels	1057:1104	Furthermore, we show that viscoelasticity and the dynamic character of the resulting hydrogels could be tuned by changing the composition, that is, the ratio between the two types of cross-links.					
35195399	8	31	theme	long-lasting	1460:1471	arg1	responsible					1512:1522	responsible	1512:1522	responsible	1512:1522	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	8	31	theme	long-lasting	1460:1471	arg1	cross-links					1496:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	11	32	theme	biomaterial	2300:2310	arg1	inks					2312:2315	biomaterial inks	2300:2315	biomaterial inks	2300:2315	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	11	33	from	bioinks	2320:2326	arg1	bioprinting					2331:2341	bioprinting	2331:2341	bioprinting	2331:2341	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	11	33	from	bioinks	2320:2326	arg1	medicine					2360:2367	regenerative medicine	2347:2367	regenerative medicine	2347:2367	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	0	34	theme	Sulfate	25:31	arg1	Hydrogels					68:76	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels	0:76	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.	0:105	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	7	35	from	processable	1322:1332	arg1	stages					1366:1371	the first stages	1356:1371	the first stages of gelation	1356:1383	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	36	theme	cross-links	1274:1284	arg1	nature					1235:1240	very dynamic nature	1222:1240	very dynamic nature	1222:1240	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	36	theme	cross-links	1274:1284	arg1	lifetime					1252:1259	short lifetime	1246:1259	short lifetime	1246:1259	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	8	37	theme	robust	1477:1482	arg1	responsible					1512:1522	responsible	1512:1522	responsible	1512:1522	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	8	37	theme	robust	1477:1482	arg1	cross-links					1496:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	4	38	theme	lifetimes	820:828	arg1	bonds					796:800	the dynamic covalent bonds	775:800	the dynamic covalent bonds of very different lifetimes	775:828	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	3	39	theme	novel	466:470	arg1	biomaterials					472:483	novel biomaterials	466:483	novel biomaterials	466:483	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	0	40	theme	Hyaluronic	37:46	arg1	Double-Network					53:66	Hyaluronic Acid Double-Network	37:66	Hyaluronic Acid Double-Network	37:66	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	7	41	used	used	1414:1417	arg2	material					1399:1406	the material	1395:1406	the material	1395:1406	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	0	42	theme	Double-Network	53:66	arg1	Hydrogels					68:76	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels	0:76	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.	0:105	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	7	43	theme	extrusion-based	1422:1436	arg1	printing					1441:1448	extrusion-based 3D printing	1422:1448	extrusion-based 3D printing	1422:1448	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	44	theme	short	1246:1250	arg1	lifetime					1252:1259	short lifetime	1246:1259	short lifetime	1246:1259	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	2	45	theme	reversible	237:246	arg1	bonds					266:270	reversible, dynamic covalent bonds	237:270	reversible, dynamic covalent bonds	237:270	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	2	46	theme	extracellular	355:367	arg1	matrix					369:374	the extracellular matrix	351:374	the extracellular matrix	351:374	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	5	47	theme	viscoelastic	987:998	arg1	hydrogels					1000:1008	viscoelastic hydrogels	987:1008	viscoelastic hydrogels	987:1008	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	3	48	theme	properties	517:526	arg1	range					508:512	a wide range	501:512	a wide range of properties required for mimicking advanced and complex tissues	501:578	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	11	49	theme	tunable	2255:2261	arg1	materials					2276:2284	novel smart and tunable viscoelastic materials	2239:2284	novel smart and tunable viscoelastic materials	2239:2284	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	2	50	dep	reversible	237:246	arg1	dynamic					249:255	dynamic	249:255	dynamic	249:255	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	9	51	dep	12	1741:1742	arg1	to					1738:1739	to	1738:1739	to	1738:1739	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	9	52	link	cross-linked	1644:1655	arg1	CS					1657:1658	the cross-linked CS	1640:1658	the cross-linked CS	1640:1658	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	11	53	theme	smart	2245:2249	arg1	materials					2276:2284	novel smart and tunable viscoelastic materials	2239:2284	novel smart and tunable viscoelastic materials	2239:2284	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	8	54	theme	mechanical	1556:1565	arg1	strength					1567:1574	mechanical strength	1556:1574	mechanical strength	1556:1574	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	3	55	theme	advanced	551:558	arg1	tissues					572:578	advanced and complex tissues	551:578	advanced and complex tissues	551:578	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	7	56	dep	injectable	1341:1350	arg1	e.g.					1335:1338	e.g.	1335:1338	e.g.	1335:1338	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	11	57	theme	covalent	2174:2181	arg1	cross-links					2183:2193	dynamic covalent cross-links	2166:2193	dynamic covalent cross-links	2166:2193	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	11	58	theme	dynamic	2166:2172	arg1	cross-links					2183:2193	dynamic covalent cross-links	2166:2193	dynamic covalent cross-links	2166:2193	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	9	59	theme	mechanical	1832:1841	arg1	properties					1843:1852	the mechanical properties	1828:1852	the mechanical properties of cartilage tissue	1828:1872	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	4	60	theme	sulfate/hyaluronic	659:676	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	7	61	dep	processable	1322:1332	arg1	injectable					1341:1350	injectable	1341:1350	injectable	1341:1350	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	61	dep	processable	1322:1332	arg1	hydrogel					1303:1310	the DN hydrogel	1296:1310	the DN hydrogel	1296:1310	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	61	dep	processable	1322:1332	arg1	processable					1322:1332	processable	1322:1332	processable	1322:1332	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	10	62	theme	degradation	2040:2050	arg1	products					2052:2059	the degradation products	2036:2059	the degradation products	2036:2059	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	2	63	theme	dynamic	330:336	arg1	character					338:346	the dynamic character	326:346	the dynamic character of the extracellular matrix	326:374	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	9	64	theme	cross-linked	1644:1655	arg1	CS					1657:1658	the cross-linked CS	1640:1658	the cross-linked CS	1640:1658	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	9	65	theme	tissue	1867:1872	arg1	properties					1843:1852	the mechanical properties	1828:1852	the mechanical properties of cartilage tissue	1828:1872	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	2	66	theme	matrix	369:374	arg1	character					338:346	the dynamic character	326:346	the dynamic character of the extracellular matrix	326:374	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	11	67	theme	DN	2148:2149	arg1	hydrogels					2151:2159	The DN hydrogels	2144:2159	The DN hydrogels with dynamic covalent cross-links	2144:2193	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	2	68	theme	covalent	257:264	arg1	bonds					266:270	reversible, dynamic covalent bonds	237:270	reversible, dynamic covalent bonds	237:270	By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix.					
35195399	6	69	theme	cross-links	1194:1204	arg1	types					1185:1189	the two types	1177:1189	the two types of cross-links	1177:1204	Furthermore, we show that viscoelasticity and the dynamic character of the resulting hydrogels could be tuned by changing the composition, that is, the ratio between the two types of cross-links.					
35195399	9	70	theme	equilibrium	1884:1894	arg1	moduli					1896:1901	the equilibrium moduli	1880:1901	the equilibrium moduli ranging from 0.3 to 0.5 MPa	1880:1929	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	3	71	theme	complex	564:570	arg1	tissues					572:578	advanced and complex tissues	551:578	advanced and complex tissues	551:578	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	9	72	theme	high	1676:1679	arg1	capacity					1690:1697	a high swelling capacity	1674:1697	a high swelling capacity (maximum swelling ratio ranging from 6 to 12)	1674:1743	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	11	73	from	inks	2312:2315	arg1	bioprinting					2331:2341	bioprinting	2331:2341	bioprinting	2331:2341	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	11	73	from	inks	2312:2315	arg1	medicine					2360:2367	regenerative medicine	2347:2367	regenerative medicine	2347:2367	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	0	74	theme	Reversible	83:92	arg1	Cross-Links					94:104	Reversible Cross-Links	83:104	Reversible Cross-Links	83:104	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	1	75	theme	necessary	167:175	arg1	requirements					177:188	necessary requirements	167:188	necessary requirements for bioprinting and injectability	167:222	Viscoelastic hydrogels are gaining interest as they possess necessary requirements for bioprinting and injectability.					
35195399	11	76	theme	regenerative	2347:2358	arg1	medicine					2360:2367	regenerative medicine	2347:2367	regenerative medicine	2347:2367	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	5	77	theme	hydrazone	899:907	arg1	adducts					851:857	Diels-Alder adducts	839:857	Diels-Alder adducts (between methylfuran and maleimide)	839:893	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	5	77	theme	hydrazone	899:907	arg1	cross-links					963:973	cross-links	963:973	cross-links	963:973	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	5	77	theme	hydrazone	899:907	arg1	bonds					909:913	hydrazone bonds	899:913	hydrazone bonds (between aldehyde and hydrazide)	899:946	Namely, Diels-Alder adducts (between methylfuran and maleimide) and hydrazone bonds (between aldehyde and hydrazide) were chosen as cross-links, leading to viscoelastic hydrogels.					
35195399	9	78	theme	maximum	1700:1706	arg1	ratio					1717:1721	maximum swelling ratio	1700:1721	maximum swelling ratio ranging from 6 to 12	1700:1742	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	4	79	theme	DN	697:698	arg1	hydrogels					700:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels	647:708	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	10	80	theme	mesenchymal	1946:1956	arg1	viable					1977:1982	viable	1977:1982	viable	1977:1982	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	10	80	theme	mesenchymal	1946:1956	arg1	cells					1966:1970	the mesenchymal stromal cells	1942:1970	the mesenchymal stromal cells	1942:1970	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	10	81	from	effect	2026:2031	arg1	macrophages					2068:2078	the macrophages	2064:2078	the macrophages	2064:2078	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	11	82	theme	materials	2276:2284	arg1	development					2224:2234	the development	2220:2234	the development of novel smart and tunable viscoelastic materials	2220:2284	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	7	83	from	stages	1366:1371	arg1	injectable					1341:1350	injectable	1341:1350	injectable	1341:1350	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	83	from	stages	1366:1371	arg1	hydrogel					1303:1310	the DN hydrogel	1296:1310	the DN hydrogel	1296:1310	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	83	from	stages	1366:1371	arg1	processable					1322:1332	processable	1322:1332	processable	1322:1332	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	3	84	theme	double-network	401:414	arg1	hydrogels					421:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	10	85	theme	further	2108:2114	arg1	applications					2130:2141	further translational applications	2108:2141	further translational applications	2108:2141	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	3	86	theme	cross-linked	384:395	arg1	hydrogels					421:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels	377:429	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	10	87	from	viable	1977:1982	arg1	presence					1991:1998	the presence	1987:1998	the presence of the hydrogels	1987:2015	Moreover, the mesenchymal stromal cells were viable in the presence of the hydrogels, and the effect of the degradation products on the macrophages suggests their safe use for further translational applications.					
35195399	0	88	theme	Chondroitin	13:23	arg1	Sulfate					25:31	Viscoelastic Chondroitin Sulfate	0:31	Viscoelastic Chondroitin Sulfate	0:31	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	1	89	theme	Viscoelastic	107:118	arg1	hydrogels					120:128	Viscoelastic hydrogels	107:128	Viscoelastic hydrogels	107:128	Viscoelastic hydrogels are gaining interest as they possess necessary requirements for bioprinting and injectability.					
35195399	7	90	theme	hydrazone	1264:1272	arg1	cross-links					1274:1284	hydrazone cross-links	1264:1284	hydrazone cross-links (∼800 s)	1264:1293	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	90	theme	hydrazone	1264:1272	arg1	s					1292:1292	∼800 s	1287:1292	∼800 s	1287:1292	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	8	91	theme	Diels-Alder	1484:1494	arg1	responsible					1512:1522	responsible	1512:1522	responsible	1512:1522	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	8	91	theme	Diels-Alder	1484:1494	arg1	cross-links					1496:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links	1451:1506	The more long-lasting and robust Diels-Alder cross-links are responsible for giving the network enhanced mechanical strength and structural stability.					
35195399	3	92	theme	bioinks	489:495	arg1	design					456:461	the design	452:461	the design of novel biomaterials and bioinks	452:495	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	0	93	theme	Acid	48:51	arg1	Double-Network					53:66	Hyaluronic Acid Double-Network	37:66	Hyaluronic Acid Double-Network	37:66	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	4	94	theme	different	810:818	arg1	lifetimes					820:828	very different lifetimes	805:828	very different lifetimes	805:828	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	3	95	theme	biomaterials	472:483	arg1	design					456:461	the design	452:461	the design of novel biomaterials and bioinks	452:495	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	9	96	theme	confinement	1757:1767	arg1	results					1769:1775	confinement results	1757:1775	confinement results in osmotically stiffened constructs	1757:1811	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	3	97	theme	wide	503:506	arg1	range					508:512	a wide range	501:512	a wide range of properties required for mimicking advanced and complex tissues	501:578	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	7	98	theme	3D	1438:1439	arg1	printing					1441:1448	extrusion-based 3D printing	1422:1448	extrusion-based 3D printing	1422:1448	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	7	99	theme	dynamic	1227:1233	arg1	nature					1235:1240	very dynamic nature	1222:1240	very dynamic nature	1222:1240	Also, due to a very dynamic nature and short lifetime of hydrazone cross-links (∼800 s), the DN hydrogel is easily processable (e.g., injectable) in the first stages of gelation, allowing the material to be used in extrusion-based 3D printing.					
35195399	11	100	theme	novel	2239:2243	arg1	materials					2276:2284	novel smart and tunable viscoelastic materials	2239:2284	novel smart and tunable viscoelastic materials	2239:2284	The DN hydrogels with dynamic covalent cross-links hold great potential for the development of novel smart and tunable viscoelastic materials to be used as biomaterial inks or bioinks in bioprinting and regenerative medicine.					
35195399	3	101	dep	double-network	401:414	arg1	DN					417:418	DN	417:418	DN	417:418	Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking advanced and complex tissues can be achieved.					
35195399	4	102	theme	covalent	787:794	arg1	bonds					796:800	the dynamic covalent bonds	775:800	the dynamic covalent bonds of very different lifetimes	775:828	In this study, we investigated the fabrication of chondroitin sulfate/hyaluronic acid (CS/HA)-based DN hydrogels, in which two networks are interpenetrated and cross-linked with the dynamic covalent bonds of very different lifetimes.					
35195399	0	103	with	Hydrogels	68:76	arg1	Cross-Links					94:104	Reversible Cross-Links	83:104	Reversible Cross-Links	83:104	Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.					
35195399	9	104	dep	0.5	1923:1925	arg1	to					1920:1921	to	1920:1921	to	1920:1921	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	9	105	theme	stiffened	1792:1800	arg1	constructs					1802:1811	osmotically stiffened constructs	1780:1811	osmotically stiffened constructs	1780:1811	Being highly charged and hydrophilic, the cross-linked CS and HA enable a high swelling capacity (maximum swelling ratio ranging from 6 to 12), which upon confinement results in osmotically stiffened constructs, able to mimic the mechanical properties of cartilage tissue, with the equilibrium moduli ranging from 0.3 to 0.5 MPa.					
35195399	1	106	contain	possess	159:165	arg1	they					154:157	they	154:157	they	154:157	Viscoelastic hydrogels are gaining interest as they possess necessary requirements for bioprinting and injectability.					
35195399	1	106	contain	possess	159:165	arg2	requirements					177:188	necessary requirements	167:188	necessary requirements for bioprinting and injectability	167:222	Viscoelastic hydrogels are gaining interest as they possess necessary requirements for bioprinting and injectability.					
37126772	8	0	with	gel	1544:1546	arg1	group					1557:1561	NIR group	1553:1561	NIR group	1553:1561	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	2	1	theme	bacterial	357:365	arg1	infections					367:376	bacterial infections	357:376	bacterial infections	357:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	1	2	theme	obstacles	244:252	arg1	one					199:201	one	199:201	one	199:201	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	1	2	theme	obstacles	244:252	arg1	infections					127:136	Pathogenic infections	116:136	Pathogenic infections	116:136	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	1	2	theme	obstacles	244:252	arg1	obstacles					244:252	the most difficult clinical treatment obstacles	206:252	the most difficult clinical treatment obstacles	206:252	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	0	3	theme	Bacteria	72:79	arg1	Capture					36:42	Targeted Capture	27:42	Targeted Capture	27:42	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	0	3	theme	Bacteria	72:79	arg1	Killing					61:67	Photothermal Killing	48:67	Photothermal Killing	48:67	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	8	4	theme	composite	1534:1542	arg1	gel					1544:1546	the composite gel	1530:1546	the composite gel with NIR group	1530:1561	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	8	5	theme	wound	1516:1520	arg1	area					1522:1525	the wound area	1512:1525	the wound area in the composite gel with NIR group	1512:1561	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	8	5	theme	wound	1516:1520	arg1	%					1575:1575	only 0.91%	1566:1575	only 0.91%	1566:1575	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	1	6	theme	public	165:170	arg1	health					172:177	public health	165:177	public health	165:177	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	0	7	theme	Wound	101:105	arg1	Healing					107:113	Wound Healing	101:113	Wound Healing	101:113	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	4	8	theme	3-aminobenzene	644:657	arg1	ABA					673:675	ABA	673:675	ABA	673:675	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	8	theme	3-aminobenzene	644:657	arg1	acid					667:670	The 3-aminobenzene boronic acid	640:670	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	9	9	theme	great	1678:1682	arg1	potential					1684:1692	great potential	1678:1692	great potential for clinical application	1678:1717	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	3	10	theme	low-temperature	584:598	arg1	sterilization					613:625	low-temperature photothermal sterilization	584:625	low-temperature photothermal sterilization	584:625	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	2	11	theme	antibacterial	288:300	arg1	technique					326:334	a promising technique	314:334	a promising technique for the treatment of bacterial infections	314:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	11	theme	antibacterial	288:300	arg1	platform					302:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	12	theme	photothermal	275:286	arg1	technique					326:334	a promising technique	314:334	a promising technique for the treatment of bacterial infections	314:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	12	theme	photothermal	275:286	arg1	platform					302:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	6	13	theme	light	1245:1249	arg1	irradiation					1251:1261	near-infrared light irradiation	1231:1261	near-infrared light irradiation	1231:1261	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	3	14	theme	heat	553:556	arg1	loss					567:570	heat transfer loss	553:570	heat transfer loss	553:570	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	8	15	from	%	1460:1460	arg1	group					1505:1509	the control group	1493:1509	the control group	1493:1509	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	7	16	theme	granulation	1315:1325	arg1	thickness					1334:1342	the granulation tissue thickness	1311:1342	the granulation tissue thickness	1311:1342	The result also demonstrates that it increases the granulation tissue thickness and collagen distribution and promotes wound healing.					
37126772	3	17	theme	photothermal	491:502	arg1	energy					504:509	photothermal energy	491:509	photothermal energy	491:509	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	6	18	theme	experiments	1119:1129	arg1	results					1101:1107	The results	1097:1107	The results of animal experiments	1097:1129	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	2	19	theme	safe	270:273	arg1	technique					326:334	a promising technique	314:334	a promising technique for the treatment of bacterial infections	314:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	19	theme	safe	270:273	arg1	platform					302:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	4	20	dep	ABA-GO/CNC/CMCS	808:822	arg1	hydrogel					834:841	composite hydrogel	824:841	the ABA-GO/CNC/CMCS composite hydrogel (composite gel)	804:857	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	20	dep	ABA-GO/CNC/CMCS	808:822	arg1	gel					854:856	composite gel	844:856	composite gel	844:856	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	21	theme	graphene	687:694	arg1	oxide					696:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	9	22	theme	clinical	1698:1705	arg1	application					1707:1717	clinical application	1698:1717	clinical application	1698:1717	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	7	23	dep	thickness	1334:1342	arg1	distribution					1357:1368	distribution	1357:1368	distribution	1357:1368	The result also demonstrates that it increases the granulation tissue thickness and collagen distribution and promotes wound healing.					
37126772	6	24	theme	animal	1112:1117	arg1	experiments					1119:1129	animal experiments	1112:1129	animal experiments	1112:1129	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	4	25	theme	-modified	677:685	arg1	oxide					696:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	8	26	theme	NIR	1553:1555	arg1	group					1557:1561	NIR group	1553:1561	NIR group	1553:1561	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	2	27	theme	promising	316:324	arg1	technique					326:334	a promising technique	314:334	a promising technique for the treatment of bacterial infections	314:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	27	theme	promising	316:324	arg1	platform					302:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	3	28	theme	normal	428:433	arg1	tissues					435:441	normal tissues	428:441	normal tissues	428:441	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	0	29	theme	Composite	0:8	arg1	Hydrogel					10:17	Composite Hydrogel	0:17	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.	0:114	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	9	30	theme	Staphylococcus	1636:1649	arg1	infection					1658:1666	Staphylococcus aureus infection	1636:1666	Staphylococcus aureus infection	1636:1666	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	4	31	theme	cellulose	753:761	arg1	CNC					780:782	CNC	780:782	CNC	780:782	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	31	theme	cellulose	753:761	arg1	nanocrystalline					763:777	cellulose nanocrystalline	753:777	cellulose nanocrystalline (CNC)	753:783	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	5	32	theme	uniform	898:904	arg1	structure					932:940	a uniform three-dimensional network structure	896:940	a uniform three-dimensional network structure	896:940	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	5	32	theme	uniform	898:904	arg1	beneficial					1020:1029	beneficial	1020:1029	beneficial	1020:1029	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	8	33	theme	wound	1479:1483	arg1	area					1485:1488	the remaining wound area	1465:1488	the remaining wound area	1465:1488	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	9	34	theme	infection	1658:1666	arg1	process					1625:1631	the wound healing process	1607:1631	the wound healing process of Staphylococcus aureus infection	1607:1666	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	3	35	theme	transfer	558:565	arg1	loss					567:570	heat transfer loss	553:570	heat transfer loss	553:570	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	8	36	theme	remaining	1445:1453	arg1	area					1485:1488	the remaining wound area	1465:1488	the remaining wound area	1465:1488	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	8	36	theme	remaining	1445:1453	arg1	%					1460:1460	the remaining 27.73%	1441:1460	the remaining 27.73% of the remaining wound area in the control group	1441:1509	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	3	37	theme	multifunctional	456:470	arg1	hydrogel					472:479	a multifunctional hydrogel	454:479	a multifunctional hydrogel driven by photothermal energy	454:509	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	8	38	from	area	1522:1525	arg1	gel					1544:1546	the composite gel	1530:1546	the composite gel with NIR group	1530:1561	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	5	39	theme	light	995:999	arg1	irradiation					1001:1011	infrared light irradiation	986:1011	infrared light irradiation	986:1011	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	6	40	theme	bacteria	1216:1223	arg1	%					1211:1211	>99.99%	1205:1211	>99.99% of bacteria	1205:1223	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	6	40	theme	bacteria	1216:1223	arg1	bacteria					1216:1223	bacteria	1216:1223	bacteria	1216:1223	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	4	41	theme	carboxymethyl	719:731	arg1	CMCS					743:746	CMCS	743:746	CMCS	743:746	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	41	theme	carboxymethyl	719:731	arg1	chitosan					733:740	carboxymethyl chitosan	719:740	carboxymethyl chitosan (CMCS)	719:747	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	5	42	theme	infection	1049:1057	arg1	bacteria					1059:1066	wound infection bacteria	1043:1066	wound infection bacteria	1043:1066	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	4	43	theme	acid	667:670	arg1	oxide					696:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	8	44	theme	area	1485:1488	arg1	area					1485:1488	the remaining wound area	1465:1488	the remaining wound area	1465:1488	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	8	44	theme	area	1485:1488	arg1	%					1460:1460	the remaining 27.73%	1441:1460	the remaining 27.73% of the remaining wound area in the control group	1441:1509	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	4	45	theme	composite	844:852	arg1	hydrogel					834:841	composite hydrogel	824:841	the ABA-GO/CNC/CMCS composite hydrogel (composite gel)	804:857	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	45	theme	composite	844:852	arg1	gel					854:856	composite gel	844:856	composite gel	844:856	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	7	46	theme	wound	1383:1387	arg1	healing					1389:1395	wound healing	1383:1395	wound healing	1383:1395	The result also demonstrates that it increases the granulation tissue thickness and collagen distribution and promotes wound healing.					
37126772	5	47	theme	obtained	864:871	arg1	gel					883:885	The obtained composite gel	860:885	The obtained composite gel	860:885	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	0	48	theme	Targeted	27:34	arg1	Capture					36:42	Targeted Capture	27:42	Targeted Capture	27:42	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	8	49	theme	control	1497:1503	arg1	group					1505:1509	the control group	1493:1509	the control group	1493:1509	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	4	50	theme	boronic	659:665	arg1	ABA					673:675	ABA	673:675	ABA	673:675	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	50	theme	boronic	659:665	arg1	acid					667:670	The 3-aminobenzene boronic acid	640:670	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide	640:700	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	9	51	theme	aureus	1651:1656	arg1	infection					1658:1666	Staphylococcus aureus infection	1636:1666	Staphylococcus aureus infection	1636:1666	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	5	52	theme	composite	873:881	arg1	gel					883:885	The obtained composite gel	860:885	The obtained composite gel	860:885	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	0	53	theme	Photothermal	48:59	arg1	Killing					61:67	Photothermal Killing	48:67	Photothermal Killing	48:67	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	5	54	theme	three-dimensional	906:922	arg1	structure					932:940	a uniform three-dimensional network structure	896:940	a uniform three-dimensional network structure	896:940	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	5	54	theme	three-dimensional	906:922	arg1	beneficial					1020:1029	beneficial	1020:1029	beneficial	1020:1029	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	9	55	theme	wound	1611:1615	arg1	healing					1617:1623	wound healing	1611:1623	the wound healing process of Staphylococcus aureus infection	1607:1666	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	0	56	dep	Capture	36:42	arg1	the					23:25	the	23:25	the	23:25	Composite Hydrogel for the Targeted Capture and Photothermal Killing of Bacteria toward Facilitating Wound Healing.					
37126772	1	57	theme	Pathogenic	116:125	arg1	one					199:201	one	199:201	one	199:201	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	1	57	theme	Pathogenic	116:125	arg1	infections					127:136	Pathogenic infections	116:136	Pathogenic infections	116:136	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	1	57	theme	Pathogenic	116:125	arg1	obstacles					244:252	the most difficult clinical treatment obstacles	206:252	the most difficult clinical treatment obstacles	206:252	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	3	58	theme	photothermal	600:611	arg1	sterilization					613:625	low-temperature photothermal sterilization	584:625	low-temperature photothermal sterilization	584:625	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	7	59	theme	tissue	1327:1332	arg1	thickness					1334:1342	the granulation tissue thickness	1311:1342	the granulation tissue thickness	1311:1342	The result also demonstrates that it increases the granulation tissue thickness and collagen distribution and promotes wound healing.					
37126772	8	60	theme	remaining	1469:1477	arg1	area					1485:1488	the remaining wound area	1465:1488	the remaining wound area	1465:1488	After treatment for 14 days, compared with the remaining 27.73% of the remaining wound area in the control group, the wound area in the composite gel with NIR group is only 0.91%.					
37126772	9	61	theme	healing	1617:1623	arg1	process					1625:1631	the wound healing process	1607:1631	the wound healing process of Staphylococcus aureus infection	1607:1666	It significantly accelerates the wound healing process of Staphylococcus aureus infection and shows great potential for clinical application.					
37126772	2	62	theme	reliable	257:264	arg1	technique					326:334	a promising technique	314:334	a promising technique for the treatment of bacterial infections	314:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	2	62	theme	reliable	257:264	arg1	platform					302:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform	255:309	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	5	63	theme	wound	1043:1047	arg1	bacteria					1059:1066	wound infection bacteria	1043:1066	wound infection bacteria	1043:1066	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	6	64	theme	composite	1145:1153	arg1	gel					1155:1157	the composite gel	1141:1157	the composite gel	1141:1157	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	5	65	theme	wound	1082:1086	arg1	healing					1088:1094	wound healing	1082:1094	wound healing	1082:1094	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	4	66	dep	chitosan	733:740	arg1	networks					785:792	networks	785:792	networks	785:792	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	3	67	theme	trapping	525:532	arg1	bacteria					534:541	trapping bacteria	525:541	trapping bacteria	525:541	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	1	68	theme	difficult	215:223	arg1	obstacles					244:252	the most difficult clinical treatment obstacles	206:252	the most difficult clinical treatment obstacles	206:252	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	5	69	theme	network	924:930	arg1	structure					932:940	a uniform three-dimensional network structure	896:940	a uniform three-dimensional network structure	896:940	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	5	69	theme	network	924:930	arg1	beneficial					1020:1029	beneficial	1020:1029	beneficial	1020:1029	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	6	70	theme	near-infrared	1231:1243	arg1	irradiation					1251:1261	near-infrared light irradiation	1231:1261	near-infrared light irradiation	1231:1261	The results of animal experiments show that the composite gel significantly reduces inflammation by killing >99.99% of bacteria under near-infrared light irradiation.					
37126772	1	71	theme	significant	145:155	arg1	risk					157:160	a significant risk	143:160	a significant risk to public health	143:177	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	1	72	theme	clinical	225:232	arg1	obstacles					244:252	the most difficult clinical treatment obstacles	206:252	the most difficult clinical treatment obstacles	206:252	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
37126772	3	73	theme	high	401:404	arg1	temperatures					406:417	high temperatures	401:417	high temperatures	401:417	Given the damage that high temperatures cause in normal tissues and cells, a multifunctional hydrogel driven by photothermal energy is created by trapping bacteria to reduce heat transfer loss and conduct low-temperature photothermal sterilization efficiently.					
37126772	5	74	theme	infrared	986:993	arg1	irradiation					1001:1011	infrared light irradiation	986:1011	infrared light irradiation	986:1011	The obtained composite gel displays a uniform three-dimensional network structure, which can be rapidly heated to 48 °C under infrared light irradiation and is beneficial for killing wound infection bacteria and promoting wound healing.					
37126772	4	75	theme	composite	824:832	arg1	hydrogel					834:841	composite hydrogel	824:841	the ABA-GO/CNC/CMCS composite hydrogel (composite gel)	804:857	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	4	75	theme	composite	824:832	arg1	gel					854:856	composite gel	844:856	composite gel	844:856	The 3-aminobenzene boronic acid (ABA)-modified graphene oxide is combined with carboxymethyl chitosan (CMCS) and cellulose nanocrystalline (CNC) networks to create the ABA-GO/CNC/CMCS composite hydrogel (composite gel).					
37126772	2	76	theme	infections	367:376	arg1	treatment					344:352	the treatment	340:352	the treatment of bacterial infections	340:376	A reliable and safe photothermal antibacterial platform is a promising technique for the treatment of bacterial infections.					
37126772	1	77	theme	treatment	234:242	arg1	obstacles					244:252	the most difficult clinical treatment obstacles	206:252	the most difficult clinical treatment obstacles	206:252	Pathogenic infections pose a significant risk to public health and are regarded as one of the most difficult clinical treatment obstacles.					
35406074	7	0	theme	stool	819:823	arg1	consistency					825:835	stool consistency	819:835	stool consistency	819:835	Gastrointestinal symptom severity was reported daily, as well as stool consistency and frequency.					
35406074	0	1	theme	Observational	86:98	arg1	Study					125:129	An Observational, Connected, Dose-Ranging Study	83:129	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.	0:152	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	12	2	theme	longer	1401:1406	arg1	chains					1408:1413	longer chains	1401:1413	longer chains	1401:1413	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	2	3	dep	40	385:386	arg1	to					382:383	to	382:383	to	382:383	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	1	4	from	important	173:181	arg1	diet					196:199	the human diet	186:199	the human diet with multiple health benefits	186:229	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	2	5	theme	fructo-oligosaccharides	308:330	arg1	tolerance					283:291	the gastrointestinal tolerance	262:291	the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres	262:367	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	0	6	from	Beet	77:80	arg1	Tolerance					17:25	Gastrointestinal Tolerance	0:25	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.	0:152	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	11	7	dep	40	1225:1226	arg1	to					1222:1223	to	1222:1223	to	1222:1223	In conclusion, scFOS intake is well tolerated up to 40 g/d in healthy subjects.					
35406074	2	8	theme	short-chain	296:306	arg1	fibres					362:367	well-known prebiotic fibres	341:367	well-known prebiotic fibres	341:367	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	2	8	theme	short-chain	296:306	arg1	scFOS					333:337	scFOS	333:337	scFOS	333:337	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	2	8	theme	short-chain	296:306	arg1	fructo-oligosaccharides					308:330	short-chain fructo-oligosaccharides	296:330	short-chain fructo-oligosaccharides (scFOS)	296:338	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	9	9	theme	Stool	983:987	arg1	consistency					989:999	Stool consistency	983:999	Stool consistency	983:999	Stool consistency stayed normal, between 3 and 5 on the Bristol stool scale, confirming that no diarrhoea appeared after scFOS intake.					
35406074	3	10	dep	observational	396:408	arg1	dose-ranging					422:433	dose-ranging	422:433	dose-ranging	422:433	An observational, connected, dose-ranging trial was conducted in 116 healthy volunteers.					
35406074	3	10	dep	observational	396:408	arg1	connected					411:419	connected	411:419	connected	411:419	An observational, connected, dose-ranging trial was conducted in 116 healthy volunteers.					
35406074	10	11	theme	normal	1159:1164	arg1	range					1166:1170	the normal range	1155:1170	the normal range	1155:1170	Stool frequency also remained within the normal range.					
35406074	12	12	theme	unique	1286:1291	arg1	composition					1293:1303	unique composition	1286:1303	unique composition	1286:1303	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	4	13	theme	first	493:497	arg1	week					499:502	the first week	489:502	the first week	489:502	During the first week, the participants were instructed to consume their usual diet.					
35406074	11	14	theme	healthy	1235:1241	arg1	subjects					1243:1250	healthy subjects	1235:1250	healthy subjects	1235:1250	In conclusion, scFOS intake is well tolerated up to 40 g/d in healthy subjects.					
35406074	12	15	theme	scFOS	1306:1310	arg1	fibres					1322:1327	scFOS prebiotic fibres	1306:1327	scFOS prebiotic fibres	1306:1327	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	11	16	theme	scFOS	1188:1192	arg1	intake					1194:1199	scFOS intake	1188:1199	scFOS intake	1188:1199	In conclusion, scFOS intake is well tolerated up to 40 g/d in healthy subjects.					
35406074	9	17	theme	scFOS	1104:1108	arg1	intake					1110:1115	scFOS intake	1104:1115	scFOS intake	1104:1115	Stool consistency stayed normal, between 3 and 5 on the Bristol stool scale, confirming that no diarrhoea appeared after scFOS intake.					
35406074	12	18	theme	short	1269:1273	arg1	chains					1275:1280	short chains	1269:1280	short chains	1269:1280	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	1	19	theme	human	190:194	arg1	diet					196:199	the human diet	186:199	the human diet with multiple health benefits	186:229	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	0	20	theme	Gastrointestinal	0:15	arg1	Tolerance					17:25	Gastrointestinal Tolerance	0:25	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.	0:152	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	4	21	theme	usual	555:559	arg1	diet					561:564	their usual diet	549:564	their usual diet	549:564	During the first week, the participants were instructed to consume their usual diet.					
35406074	5	22	theme	g	624:624	arg1	scFOS					626:630	15 g scFOS	621:630	15 g scFOS	621:630	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	5	23	theme	second	578:583	arg1	week					585:588	the second week	574:588	the second week	574:588	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	0	24	dep	Observational	86:98	arg1	Dose-Ranging					112:123	Dose-Ranging	112:123	Dose-Ranging	112:123	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	0	24	dep	Observational	86:98	arg1	Connected					101:109	Connected	101:109	Connected	101:109	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	7	25	theme	symptom	771:777	arg1	severity					779:786	Gastrointestinal symptom severity	754:786	Gastrointestinal symptom severity	754:786	Gastrointestinal symptom severity was reported daily, as well as stool consistency and frequency.					
35406074	0	26	theme	Short-Chain	30:40	arg1	Fructo-Oligosaccharides					42:64	Short-Chain Fructo-Oligosaccharides	30:64	Short-Chain Fructo-Oligosaccharides	30:64	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	6	27	theme	scFOS	713:717	arg1	dose					719:722	the scFOS dose	709:722	the scFOS dose	709:722	For the third week, the scFOS dose was doubled for all subjects.					
35406074	0	28	theme	Healthy	134:140	arg1	Volunteers					142:151	Healthy Volunteers	134:151	Healthy Volunteers	134:151	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	8	29	theme	reported	917:924	arg1	symptoms					926:933	all reported symptoms	913:933	all reported symptoms	913:933	The results show that scFOS are well tolerated up to 40 g/d; all reported symptoms remained very mild from a clinical perspective.					
35406074	8	30	dep	40	905:906	arg1	to					902:903	to	902:903	to	902:903	The results show that scFOS are well tolerated up to 40 g/d; all reported symptoms remained very mild from a clinical perspective.					
35406074	3	31	theme	healthy	462:468	arg1	volunteers					470:479	116 healthy volunteers	458:479	116 healthy volunteers	458:479	An observational, connected, dose-ranging trial was conducted in 116 healthy volunteers.					
35406074	12	32	theme	inulin-type	1375:1385	arg1	fructans					1387:1394	inulin-type fructans	1375:1394	inulin-type fructans with longer chains	1375:1413	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	1	33	theme	multiple	206:213	arg1	benefits					222:229	multiple health benefits	206:229	multiple health benefits	206:229	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	8	34	theme	clinical	961:968	arg1	perspective					970:980	a clinical perspective	959:980	a clinical perspective	959:980	The results show that scFOS are well tolerated up to 40 g/d; all reported symptoms remained very mild from a clinical perspective.					
35406074	5	35	theme	subjects	603:610	arg1	half					591:594	half	591:594	half of the subjects consumed 15 g scFOS per day	591:638	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	5	35	theme	subjects	603:610	arg1	half					655:658	the other half	645:658	the other half	645:658	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	5	36	theme	g	672:672	arg1	scFOS					674:678	20 g scFOS	669:678	20 g scFOS	669:678	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	9	37	from	3	1024:1024	arg1	scale					1053:1057	the Bristol stool scale	1035:1057	the Bristol stool scale	1035:1057	Stool consistency stayed normal, between 3 and 5 on the Bristol stool scale, confirming that no diarrhoea appeared after scFOS intake.					
35406074	7	38	theme	Gastrointestinal	754:769	arg1	severity					779:786	Gastrointestinal symptom severity	754:786	Gastrointestinal symptom severity	754:786	Gastrointestinal symptom severity was reported daily, as well as stool consistency and frequency.					
35406074	1	39	theme	health	215:220	arg1	benefits					222:229	multiple health benefits	206:229	multiple health benefits	206:229	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	0	40	theme	Fructo-Oligosaccharides	42:64	arg1	Tolerance					17:25	Gastrointestinal Tolerance	0:25	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.	0:152	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	3	41	theme	observational	396:408	arg1	trial					435:439	An observational, connected, dose-ranging trial	393:439	An observational, connected, dose-ranging trial	393:439	An observational, connected, dose-ranging trial was conducted in 116 healthy volunteers.					
35406074	8	42	from	perspective	970:980	arg1	mild					949:952	mild	949:952	mild	949:952	The results show that scFOS are well tolerated up to 40 g/d; all reported symptoms remained very mild from a clinical perspective.					
35406074	12	43	theme	fructans	1387:1394	arg1	types					1366:1370	other types	1360:1370	other types of inulin-type fructans with longer chains	1360:1413	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	12	44	theme	prebiotic	1312:1320	arg1	fibres					1322:1327	scFOS prebiotic fibres	1306:1327	scFOS prebiotic fibres	1306:1327	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	0	45	theme	Sugar	71:75	arg1	Beet					77:80	Sugar Beet	71:80	Sugar Beet	71:80	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	1	46	with	diet	196:199	arg1	benefits					222:229	multiple health benefits	206:229	multiple health benefits	206:229	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	0	47	from	Study	125:129	arg1	Volunteers					142:151	Healthy Volunteers	134:151	Healthy Volunteers	134:151	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	13	48	theme	fibres	1443:1448	arg1	tolerance					1430:1438	The digestive tolerance	1416:1438	The digestive tolerance of fibres	1416:1448	The digestive tolerance of fibres should be considered when added to foods and beverages.					
35406074	6	49	theme	third	697:701	arg1	week					703:706	the third week	693:706	the third week	693:706	For the third week, the scFOS dose was doubled for all subjects.					
35406074	5	50	theme	other	649:653	arg1	half					655:658	the other half	645:658	the other half	645:658	During the second week, half of the subjects consumed 15 g scFOS per day, and the other half consumed 20 g scFOS per day.					
35406074	2	51	dep	g/d	388:390	arg1	40					385:386	40	385:386	40	385:386	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	2	52	theme	gastrointestinal	266:281	arg1	tolerance					283:291	the gastrointestinal tolerance	262:291	the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres	262:367	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	9	53	theme	Bristol	1039:1045	arg1	scale					1053:1057	the Bristol stool scale	1035:1057	the Bristol stool scale	1035:1057	Stool consistency stayed normal, between 3 and 5 on the Bristol stool scale, confirming that no diarrhoea appeared after scFOS intake.					
35406074	2	54	theme	prebiotic	352:360	arg1	fibres					362:367	well-known prebiotic fibres	341:367	well-known prebiotic fibres	341:367	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	2	54	theme	prebiotic	352:360	arg1	fructo-oligosaccharides					308:330	short-chain fructo-oligosaccharides	296:330	short-chain fructo-oligosaccharides (scFOS)	296:338	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	13	55	theme	digestive	1420:1428	arg1	tolerance					1430:1438	The digestive tolerance	1416:1438	The digestive tolerance of fibres	1416:1448	The digestive tolerance of fibres should be considered when added to foods and beverages.					
35406074	2	56	dep	doses	373:377	arg1	g/d					388:390	g/d	388:390	g/d	388:390	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	9	57	theme	stool	1047:1051	arg1	scale					1053:1057	the Bristol stool scale	1035:1057	the Bristol stool scale	1035:1057	Stool consistency stayed normal, between 3 and 5 on the Bristol stool scale, confirming that no diarrhoea appeared after scFOS intake.					
35406074	2	58	theme	well-known	341:350	arg1	fibres					362:367	well-known prebiotic fibres	341:367	well-known prebiotic fibres	341:367	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	2	58	theme	well-known	341:350	arg1	fructo-oligosaccharides					308:330	short-chain fructo-oligosaccharides	296:330	short-chain fructo-oligosaccharides (scFOS)	296:338	This study aimed to determine the gastrointestinal tolerance of short-chain fructo-oligosaccharides (scFOS), well-known prebiotic fibres, at doses up to 40 g/d.					
35406074	12	59	theme	other	1360:1364	arg1	types					1366:1370	other types	1360:1370	other types of inulin-type fructans with longer chains	1360:1413	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	0	60	dep	Tolerance	17:25	arg1	Study					125:129	An Observational, Connected, Dose-Ranging Study	83:129	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.	0:152	Gastrointestinal Tolerance of Short-Chain Fructo-Oligosaccharides from Sugar Beet: An Observational, Connected, Dose-Ranging Study in Healthy Volunteers.					
35406074	1	61	from	diet	196:199	arg1	important					173:181	important	173:181	important	173:181	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	1	62	theme	Dietary	154:160	arg1	fibres					162:167	Dietary fibres	154:167	Dietary fibres	154:167	Dietary fibres are important in the human diet with multiple health benefits.					
35406074	10	63	theme	Stool	1118:1122	arg1	frequency					1124:1132	Stool frequency	1118:1132	Stool frequency	1118:1132	Stool frequency also remained within the normal range.					
35406074	12	64	with	fructans	1387:1394	arg1	chains					1408:1413	longer chains	1401:1413	longer chains	1401:1413	Thanks to their short chains and unique composition, scFOS prebiotic fibres are much better tolerated than other types of inulin-type fructans with longer chains.					
35406074	11	65	dep	g/d	1228:1230	arg1	subjects					1243:1250	healthy subjects	1235:1250	healthy subjects	1235:1250	In conclusion, scFOS intake is well tolerated up to 40 g/d in healthy subjects.					
35868745	3	0	theme	foam	288:291	arg1	absorbent					297:305	a composite foam oil absorbent	276:305	a composite foam oil absorbent	276:305	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	2	1	theme	Porous	123:128	arg1	foams					130:134	Porous foams	123:134	Porous foams	123:134	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	5	2	theme	high	754:757	arg1	absorption					763:772	high oil absorption	754:772	high oil absorption	754:772	Interconnected skeleton decorated by oleophilic gelators contributes to high oil absorption.					
35868745	4	3	theme	chemical	659:666	arg1	modification					668:679	traditional hydrophobic chemical modification	635:679	traditional hydrophobic chemical modification	635:679	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	4	4	theme	long	526:529	arg1	chains					537:542	long alkyl chains	526:542	long alkyl chains of gelator	526:553	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	3	5	theme	oil	293:295	arg1	absorbent					297:305	a composite foam oil absorbent	276:305	a composite foam oil absorbent	276:305	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	4	6	from	t-butanol	496:504	arg1	solvent					513:519	the solvent	509:519	the solvent	509:519	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	6	7	theme	3D	817:818	arg1	network					820:826	3D network	817:826	3D network	817:826	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	4	8	theme	hydrophobic	647:657	arg1	modification					668:679	traditional hydrophobic chemical modification	635:679	traditional hydrophobic chemical modification	635:679	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	3	9	theme	absorption	322:331	arg1	capable					307:313	capable	307:313	capable	307:313	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	6	10	theme	oil	882:884	arg1	retention					886:894	effective oil retention	872:894	effective oil retention	872:894	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	6	11	theme	effective	872:880	arg1	retention					886:894	effective oil retention	872:894	effective oil retention	872:894	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	7	12	dep	abundant	977:984	arg1	low-cost					987:994	low-cost	987:994	low-cost	987:994	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	4	13	theme	alkyl	531:535	arg1	chains					537:542	long alkyl chains	526:542	long alkyl chains of gelator	526:553	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	5	14	theme	oil	759:761	arg1	absorption					763:772	high oil absorption	754:772	high oil absorption	754:772	Interconnected skeleton decorated by oleophilic gelators contributes to high oil absorption.					
35868745	1	15	theme	Oil	71:73	arg1	spills					75:80	Oil spills	71:80	Oil spills	71:80	Oil spills threaten ecosystem and health seriously.					
35868745	3	16	theme	aluminum	394:401	arg1	gelator					416:422	hydroxyl aluminum stearate oil gelator	385:422	hydroxyl aluminum stearate oil gelator	385:422	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	3	17	theme	oil	318:320	arg1	absorption					322:331	oil absorption	318:331	oil absorption	318:331	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	4	18	theme	foam	456:459	arg1	microstructure					429:442	The microstructure	425:442	The microstructure of alginate foam	425:459	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	0	19	theme	effective	40:48	arg1	treatment					60:68	effective oil spill treatment	40:68	effective oil spill treatment	40:68	Alginate-oil gelator composite foam for effective oil spill treatment.					
35868745	3	20	theme	stearate	403:410	arg1	gelator					416:422	hydroxyl aluminum stearate oil gelator	385:422	hydroxyl aluminum stearate oil gelator	385:422	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	4	21	theme	alginate	447:454	arg1	foam					456:459	alginate foam	447:459	alginate foam	447:459	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	6	22	theme	Oleophilic	775:784	arg1	gelator					786:792	Oleophilic gelator	775:792	Oleophilic gelator	775:792	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	3	23	theme	porous	360:365	arg1	foam					376:379	porous alginate foam	360:379	porous alginate foam	360:379	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	4	24	from	solvent	513:519	arg1	addition					484:491	the addition	480:491	the addition of t-butanol in the solvent	480:519	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	6	25	theme	oil	950:952	arg1	retention					954:962	oil retention	950:962	oil retention	950:962	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	3	26	theme	hydroxyl	385:392	arg1	gelator					416:422	hydroxyl aluminum stearate oil gelator	385:422	hydroxyl aluminum stearate oil gelator	385:422	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	3	27	theme	oil	337:339	arg1	gelation					341:348	oil gelation	337:348	oil gelation	337:348	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	2	28	with	many	202:205	arg1	re-bleeding					232:242	re-bleeding	232:242	re-bleeding	232:242	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	2	28	with	many	202:205	arg1	retention					221:229	poor oil retention	212:229	poor oil retention (re-bleeding)	212:243	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	7	29	theme	oil	1043:1045	arg1	spills					1047:1052	oil spills	1043:1052	oil spills	1043:1052	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	4	30	from	addition	484:491	arg1	solvent					513:519	the solvent	509:519	the solvent	509:519	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	0	31	theme	composite	21:29	arg1	foam					31:34	composite foam	21:34	composite foam for effective oil spill treatment	21:68	Alginate-oil gelator composite foam for effective oil spill treatment.					
35868745	6	32	theme	absorption	935:944	arg1	retention					954:962	oil retention	950:962	oil retention	950:962	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	6	32	theme	absorption	935:944	arg1	integration					911:921	the integration	907:921	the integration of high oil absorption	907:944	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	2	33	theme	oil	177:179	arg1	absorbents					181:190	oil absorbents	177:190	oil absorbents	177:190	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	3	34	theme	alginate	367:374	arg1	foam					376:379	porous alginate foam	360:379	porous alginate foam	360:379	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	6	35	theme	oil	931:933	arg1	absorption					935:944	high oil absorption	926:944	high oil absorption	926:944	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	5	36	theme	Interconnected	682:695	arg1	skeleton					697:704	Interconnected skeleton	682:704	Interconnected skeleton decorated by oleophilic gelators	682:737	Interconnected skeleton decorated by oleophilic gelators contributes to high oil absorption.					
35868745	2	37	theme	oil	217:219	arg1	re-bleeding					232:242	re-bleeding	232:242	re-bleeding	232:242	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	2	37	theme	oil	217:219	arg1	retention					221:229	poor oil retention	212:229	poor oil retention (re-bleeding)	212:243	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	4	38	theme	secondary	610:618	arg1	pollution					620:628	secondary pollution	610:628	secondary pollution from traditional hydrophobic chemical modification	610:679	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	3	39	theme	oil	412:414	arg1	gelator					416:422	hydroxyl aluminum stearate oil gelator	385:422	hydroxyl aluminum stearate oil gelator	385:422	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	6	40	theme	high	926:929	arg1	absorption					935:944	high oil absorption	926:944	high oil absorption	926:944	Oleophilic gelator can self-assemble into 3D network to entrap oils to form gels, giving rise to effective oil retention, realizing the integration of high oil absorption and oil retention.					
35868745	2	41	theme	poor	212:215	arg1	re-bleeding					232:242	re-bleeding	232:242	re-bleeding	232:242	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	2	41	theme	poor	212:215	arg1	retention					221:229	poor oil retention	212:229	poor oil retention (re-bleeding)	212:243	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	4	42	theme	good	580:583	arg1	hydrophobicity					585:598	good hydrophobicity	580:598	good hydrophobicity	580:598	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	0	43	theme	spill	54:58	arg1	treatment					60:68	effective oil spill treatment	40:68	effective oil spill treatment	40:68	Alginate-oil gelator composite foam for effective oil spill treatment.					
35868745	2	44	theme	ideal	156:160	arg1	candidates					162:171	ideal candidates	156:171	ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding)	156:243	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	7	45	theme	composite	996:1004	arg1	foam					1006:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	7	45	theme	composite	996:1004	arg1	promising					1020:1028	promising	1020:1028	promising	1020:1028	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	0	46	theme	oil	50:52	arg1	treatment					60:68	effective oil spill treatment	40:68	effective oil spill treatment	40:68	Alginate-oil gelator composite foam for effective oil spill treatment.					
35868745	4	47	theme	t-butanol	496:504	arg1	addition					484:491	the addition	480:491	the addition of t-butanol in the solvent	480:519	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	3	48	theme	composite	278:286	arg1	absorbent					297:305	a composite foam oil absorbent	276:305	a composite foam oil absorbent	276:305	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	2	49	theme	many	202:205	arg1	absorbents					181:190	oil absorbents	177:190	oil absorbents	177:190	Porous foams have been proved as ideal candidates for oil absorbents, however, many with poor oil retention (re-bleeding).					
35868745	7	50	theme	abundant	977:984	arg1	foam					1006:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	7	50	theme	abundant	977:984	arg1	promising					1020:1028	promising	1020:1028	promising	1020:1028	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	4	51	theme	gelator	547:553	arg1	chains					537:542	long alkyl chains	526:542	long alkyl chains of gelator	526:553	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	7	52	theme	natural	969:975	arg1	foam					1006:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam	965:1009	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	7	52	theme	natural	969:975	arg1	promising					1020:1028	promising	1020:1028	promising	1020:1028	The natural abundant, low-cost composite foam would be promising for tackling oil spills.					
35868745	4	53	theme	traditional	635:645	arg1	modification					668:679	traditional hydrophobic chemical modification	635:679	traditional hydrophobic chemical modification	635:679	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	4	54	from	modification	668:679	arg1	pollution					620:628	secondary pollution	610:628	secondary pollution from traditional hydrophobic chemical modification	610:679	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	4	55	theme	foam	561:564	arg1	skeleton					566:573	foam skeleton	561:573	foam skeleton	561:573	The microstructure of alginate foam can be adjusted by the addition of t-butanol in the solvent, and long alkyl chains of gelator endow foam skeleton with good hydrophobicity, avoiding secondary pollution from traditional hydrophobic chemical modification.					
35868745	3	56	theme	capable	307:313	arg1	absorbent					297:305	a composite foam oil absorbent	276:305	a composite foam oil absorbent	276:305	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	3	57	theme	gelation	341:348	arg1	capable					307:313	capable	307:313	capable	307:313	Here, we creatively developed a composite foam oil absorbent capable of oil absorption and oil gelation, based on porous alginate foam and hydroxyl aluminum stearate oil gelator.					
35868745	5	58	theme	oleophilic	719:728	arg1	gelators					730:737	oleophilic gelators	719:737	oleophilic gelators	719:737	Interconnected skeleton decorated by oleophilic gelators contributes to high oil absorption.					
35137077	10	0	from	specificity	1707:1717	arg1	GH29					1722:1725	GH29	1722:1725	GH29	1722:1725	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	4	1	theme	\text	749:753	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	6	2	theme	uncultured	1167:1176	arg1	sp					1230:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	2	3	theme	\text	283:287	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	3	theme	\text	283:287	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	9	4	theme	Lewis	1507:1511	arg1	antigen					1515:1521	the Lewis Y antigen	1503:1521	the Lewis Y antigen	1503:1521	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	4	5	theme	L	755:755	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	1	6	theme	marine	202:207	arg1	environments					225:236	marine and terrestrial environments	202:236	environments	225:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	5	7	theme	GH29	1075:1078	arg1	enzymes					1080:1086	only four marine GH29 enzymes	1058:1086	only four marine GH29 enzymes	1058:1086	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	11	8	theme	α1,4	1827:1830	arg1	GlcNAc					1832:1837	Fuc(α1,4)GlcNAc	1823:1837	Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM	1823:1873	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	4	9	theme	α-	746:747	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	2	10	theme	group	462:466	arg1	system					468:473	the Lewis blood group system	446:473	the Lewis blood group system	446:473	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	3	11	theme	carbohydrate-active	642:660	arg1	families					676:683	different carbohydrate-active enzyme (CAZy) families	632:683	different carbohydrate-active enzyme (CAZy) families	632:683	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	9	12	theme	Y	1513:1513	arg1	antigen					1515:1521	the Lewis Y antigen	1503:1521	the Lewis Y antigen	1503:1521	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	2	13	dep	signaling	506:514	arg1	stimulation					536:546	stimulation	536:546	stimulation	536:546	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	12	14	theme	GH29	1928:1931	arg1	members					1940:1946	GH29 family members	1928:1946	GH29 family members	1928:1946	Altogether, the findings extend our knowledge about GH29 family members from the marine environment, which are so far largely unexplored.					
35137077	4	15	theme	glycans	793:799	arg1	ends					785:788	non-reducing ends	772:788	non-reducing ends of glycans	772:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	1	16	from	-hexose	191:197	arg1	environments					225:236	marine and terrestrial environments	202:236	environments	225:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	4	17	from	ends	785:788	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	10	18	theme	Fuc	1666:1668	arg1	specificity					1707:1717	a previously unreported specificity	1683:1717	a previously unreported specificity in GH29	1683:1725	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	10	18	theme	Fuc	1666:1668	arg1	GlcNAc					1675:1680	Fuc(α1,4)GlcNAc	1666:1680	Fuc(α1,4)GlcNAc	1666:1680	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	1	19	theme	$	180:180	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	19	theme	$	180:180	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	4	20	theme	$	758:758	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	5	21	theme	terrestrial	922:932	arg1	environments					934:945	terrestrial environments	922:945	terrestrial environments	922:945	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	11	22	with	enzyme	1749:1754	arg1	pH					1761:1762	pH	1761:1762	pH	1761:1762	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	22	with	enzyme	1749:1754	arg1	optima					1780:1785	temperature optima	1768:1785	temperature optima	1768:1785	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	2	23	theme	blood	456:460	arg1	system					468:473	the Lewis blood group system	446:473	the Lewis blood group system	446:473	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	6	24	theme	marine	1197:1202	arg1	sp					1230:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	11	25	theme	Fuc	1823:1825	arg1	GlcNAc					1832:1837	Fuc(α1,4)GlcNAc	1823:1837	Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM	1823:1873	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	1	26	theme	$	129:129	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	26	theme	$	129:129	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	4	27	theme	substrate	844:852	arg1	compositions					854:865	different substrate compositions	834:865	different substrate compositions	834:865	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	1	28	theme	functional	264:273	arg1	roles					275:279	functional roles	264:279	functional roles	264:279	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	10	29	theme	α1,4	1670:1673	arg1	specificity					1707:1717	a previously unreported specificity	1683:1717	a previously unreported specificity in GH29	1683:1725	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	10	29	theme	α1,4	1670:1673	arg1	GlcNAc					1675:1680	Fuc(α1,4)GlcNAc	1666:1680	Fuc(α1,4)GlcNAc	1666:1680	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	1	30	theme	{	135:135	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	30	theme	{	135:135	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	8	31	theme	synthetic	1366:1374	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	9	32	theme	α1,6	1597:1600	arg1	GlcNAc					1602:1607	Fuc(α1,6)GlcNAc	1593:1607	Fuc(α1,6)GlcNAc	1593:1607	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	5	33	from	environments	934:945	arg1	fucosidases					905:915	several GH29 fucosidases	892:915	several GH29 fucosidases from terrestrial environments	892:945	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	5	34	theme	GH29	1015:1018	arg1	members					1004:1010	marine members	997:1010	marine members of GH29 and their substrate specificities	997:1052	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	8	35	theme	CNP-α-	1386:1391	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	2	36	theme	milk	413:416	arg1	HMOs					436:439	HMOs	436:439	HMOs	436:439	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	36	theme	milk	413:416	arg1	oligosaccharides					418:433	human milk oligosaccharides	407:433	human milk oligosaccharides (HMOs)	407:440	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	37	from	walls	370:374	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	37	from	walls	370:374	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	11	38	theme	monomeric	1739:1747	arg1	enzyme					1749:1754	a monomeric enzyme	1737:1754	a monomeric enzyme with pH and temperature optima	1737:1785	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	38	theme	monomeric	1739:1747	arg1	Fp231					1728:1732	Fp231	1728:1732	Fp231	1728:1732	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	2	39	theme	cell	365:368	arg1	walls					370:374	cell walls	365:374	cell walls of brown algae	365:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	8	40	theme	L	1399:1399	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	9	41	theme	fucose-containing	1437:1453	arg1	oligosaccharides					1455:1470	up to 17 fucose-containing oligosaccharides	1428:1470	up to 17 fucose-containing oligosaccharides	1428:1470	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	2	42	theme	algae	385:389	arg1	walls					370:374	cell walls	365:374	cell walls of brown algae	365:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	10	43	theme	unreported	1696:1705	arg1	specificity					1707:1717	a previously unreported specificity	1683:1717	a previously unreported specificity in GH29	1683:1725	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	10	43	theme	unreported	1696:1705	arg1	GlcNAc					1675:1680	Fuc(α1,4)GlcNAc	1666:1680	Fuc(α1,4)GlcNAc	1666:1680	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	4	44	theme	family	721:726	arg1	Fucosidases					686:696	Fucosidases	686:696	Fucosidases of glycoside hydrolase family 29 (GH29)	686:736	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	0	45	theme	family	32:37	arg1	hydrolases					52:61	five marine family 29 glycoside hydrolases	20:61	five marine family 29 glycoside hydrolases	20:61	Characterization of five marine family 29 glycoside hydrolases reveals an α-L-fucosidase targeting specifically Fuc(α1,4)GlcNAc.					
35137077	2	46	theme	brown	379:383	arg1	algae					385:389	brown algae	379:389	brown algae	379:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	5	47	theme	GH29	900:903	arg1	fucosidases					905:915	several GH29 fucosidases	892:915	several GH29 fucosidases from terrestrial environments	892:945	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	2	48	from	important	488:496	arg1	response					527:534	immune response	520:534	immune response	520:534	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	48	from	important	488:496	arg1	signaling					506:514	cell signaling	501:514	cell signaling	501:514	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	49	theme	$	282:282	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	49	theme	$	282:282	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	0	50	theme	glycoside	42:50	arg1	hydrolases					52:61	five marine family 29 glycoside hydrolases	20:61	five marine family 29 glycoside hydrolases	20:61	Characterization of five marine family 29 glycoside hydrolases reveals an α-L-fucosidase targeting specifically Fuc(α1,4)GlcNAc.					
35137077	5	51	theme	specificities	1040:1052	arg1	members					1004:1010	marine members	997:1010	marine members of GH29 and their substrate specificities	997:1052	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	3	52	theme	fucose	560:565	arg1	Removal					549:555	Removal	549:555	Removal of fucose from these biomolecules	549:589	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	9	53	theme	Fuc	1593:1595	arg1	GlcNAc					1602:1607	Fuc(α1,6)GlcNAc	1593:1607	Fuc(α1,6)GlcNAc	1593:1607	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	1	54	theme	\text	181:185	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	54	theme	\text	181:185	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	2	55	from	monosaccharide	314:327	arg1	fucoidan					351:358	the polysaccharide fucoidan	332:358	the polysaccharide fucoidan	332:358	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	8	56	dep	enzymes	1304:1310	arg1	Fp251					1334:1338	Fp251	1334:1338	Fp251	1334:1338	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	8	56	dep	enzymes	1304:1310	arg1	enzymes					1304:1310	All five enzymes	1295:1310	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284)	1295:1349	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	8	56	dep	enzymes	1304:1310	arg1	Fp239					1320:1324	Fp239	1320:1324	Fp239	1320:1324	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	8	56	dep	enzymes	1304:1310	arg1	Fp284					1344:1348	Fp284	1344:1348	Fp284	1344:1348	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	4	57	theme	glycoside	701:709	arg1	family					721:726	glycoside hydrolase family 29	701:729	glycoside hydrolase family 29 (GH29)	701:736	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	4	57	theme	glycoside	701:709	arg1	GH29					732:735	GH29	732:735	GH29	732:735	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	1	58	theme	L	187:187	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	58	theme	L	187:187	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	6	59	theme	fucoidan-degrading	1178:1195	arg1	sp					1230:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	2	60	theme	{	288:288	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	60	theme	{	288:288	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	1	61	theme	$	190:190	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	61	theme	$	190:190	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	4	62	theme	$	748:748	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	4	63	theme	{	754:754	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	11	64	from	25°C	1805:1808	arg1	enzyme					1749:1754	a monomeric enzyme	1737:1754	a monomeric enzyme with pH and temperature optima	1737:1785	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	64	from	25°C	1805:1808	arg1	Fp231					1728:1732	Fp231	1728:1732	Fp231	1728:1732	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	65	with	GlcNAc	1832:1837	arg1	kcat = 1.3 s-1					1844:1857	kcat = 1.3 s-1	1844:1857	kcat = 1.3 s-1	1844:1857	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	65	with	GlcNAc	1832:1837	arg1	Km = 660 μM					1863:1873	Km = 660 μM	1863:1873	Km = 660 μM	1863:1873	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	2	66	theme	cell	501:504	arg1	signaling					506:514	cell signaling	501:514	cell signaling	501:514	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	6	67	theme	GH29	1130:1133	arg1	fucosidases					1135:1145	five GH29 fucosidases	1125:1145	five GH29 fucosidases	1125:1145	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	10	68	theme	strict	1639:1644	arg1	specificity					1646:1656	strict specificity	1639:1656	strict specificity	1639:1656	Furthermore, Fp231 displayed strict specificity against Fuc(α1,4)GlcNAc, a previously unreported specificity in GH29.					
35137077	12	69	theme	marine	1957:1962	arg1	environment					1964:1974	the marine environment	1953:1974	the marine environment	1953:1974	Altogether, the findings extend our knowledge about GH29 family members from the marine environment, which are so far largely unexplored.					
35137077	3	70	theme	enzyme	662:667	arg1	families					676:683	different carbohydrate-active enzyme (CAZy) families	632:683	different carbohydrate-active enzyme (CAZy) families	632:683	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	4	71	theme	non-reducing	772:783	arg1	ends					785:788	non-reducing ends	772:788	non-reducing ends of glycans	772:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	11	72	from	pH 5.6-6.0	1790:1799	arg1	enzyme					1749:1754	a monomeric enzyme	1737:1754	a monomeric enzyme with pH and temperature optima	1737:1785	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	11	72	from	pH 5.6-6.0	1790:1799	arg1	Fp231					1728:1732	Fp231	1728:1732	Fp231	1728:1732	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	3	73	theme	different	632:640	arg1	families					676:683	different carbohydrate-active enzyme (CAZy) families	632:683	different carbohydrate-active enzyme (CAZy) families	632:683	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	1	74	theme	distributed	168:178	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	74	theme	distributed	168:178	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	12	75	theme	family	1933:1938	arg1	members					1940:1946	GH29 family members	1928:1946	GH29 family members	1928:1946	Altogether, the findings extend our knowledge about GH29 family members from the marine environment, which are so far largely unexplored.					
35137077	3	76	from	biomolecules	578:589	arg1	Removal					549:555	Removal	549:555	Removal of fucose from these biomolecules	549:589	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	6	77	theme	Paraglaciecola	1215:1228	arg1	sp					1230:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	4	78	theme	}	756:756	arg1	-fucose					759:765	α-$\text{L} $-fucose	746:765	α-$\text{L} $-fucose from non-reducing ends of glycans	746:799	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	3	79	theme	CAZy	670:673	arg1	families					676:683	different carbohydrate-active enzyme (CAZy) families	632:683	different carbohydrate-active enzyme (CAZy) families	632:683	Removal of fucose from these biomolecules is catalyzed by fucosidases belonging to different carbohydrate-active enzyme (CAZy) families.					
35137077	6	80	theme	bacterium	1204:1212	arg1	sp					1230:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp	1164:1231	Here, five GH29 fucosidases originating from an uncultured fucoidan-degrading marine bacterium (Paraglaciecola sp.)					
35137077	2	81	theme	Lewis	450:454	arg1	system					468:473	the Lewis blood group system	446:473	the Lewis blood group system	446:473	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	82	from	response	527:534	arg1	important					488:496	important	488:496	important	488:496	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	1	83	theme	\text	130:134	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	83	theme	\text	130:134	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	4	84	theme	different	834:842	arg1	compositions					854:865	different substrate compositions	834:865	different substrate compositions	834:865	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	8	85	theme	substrate	1376:1384	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	9	86	dep	17	1434:1435	arg1	to					1431:1432	to	1431:1432	to	1431:1432	Assayed against up to 17 fucose-containing oligosaccharides, Fp239 showed activity against the Lewis Y antigen, 2'- and 3-fucosyllactose, while Fp284 degraded 2'-fucosyllactose and Fuc(α1,6)GlcNAc.					
35137077	1	87	theme	roles	275:279	arg1	variety					253:259	a variety	251:259	a variety of functional roles	251:279	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	87	theme	roles	275:279	arg1	roles					275:279	functional roles	264:279	functional roles	264:279	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	88	theme	L	136:136	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	88	theme	L	136:136	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	8	89	theme	$	1392:1392	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	0	90	theme	Fuc	112:114	arg1	GlcNAc					121:126	Fuc(α1,4)GlcNAc	112:126	Fuc(α1,4)GlcNAc	112:126	Characterization of five marine family 29 glycoside hydrolases reveals an α-L-fucosidase targeting specifically Fuc(α1,4)GlcNAc.					
35137077	2	91	located	found	398:402	arg2	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	91	located	found	398:402	arg2	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	91	located	found	398:402	arg1	oligosaccharides					418:433	human milk oligosaccharides	407:433	human milk oligosaccharides (HMOs)	407:440	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	91	located	found	398:402	arg1	HMOs					436:439	HMOs	436:439	HMOs	436:439	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	91	located	found	398:402	arg1	system					468:473	the Lewis blood group system	446:473	the Lewis blood group system	446:473	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	8	92	theme	{	1398:1398	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	2	93	theme	immune	520:525	arg1	response					527:534	immune response	520:534	immune response	520:534	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	94	theme	human	407:411	arg1	HMOs					436:439	HMOs	436:439	HMOs	436:439	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	94	theme	human	407:411	arg1	oligosaccharides					418:433	human milk oligosaccharides	407:433	human milk oligosaccharides (HMOs)	407:440	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	5	95	theme	marine	997:1002	arg1	members					1004:1010	marine members	997:1010	marine members of GH29 and their substrate specificities	997:1052	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	8	96	theme	\text	1393:1397	arg1	}					1400:1400	the synthetic substrate CNP-α-$\text{L}	1362:1400	the synthetic substrate CNP-α-$\text{L} $-fucose	1362:1409	All five enzymes (Fp231, Fp239, Fp240, Fp251 and Fp284) hydrolyzed the synthetic substrate CNP-α-$\text{L} $-fucose.					
35137077	0	97	theme	marine	25:30	arg1	hydrolases					52:61	five marine family 29 glycoside hydrolases	20:61	five marine family 29 glycoside hydrolases	20:61	Characterization of five marine family 29 glycoside hydrolases reveals an α-L-fucosidase targeting specifically Fuc(α1,4)GlcNAc.					
35137077	1	98	theme	terrestrial	213:223	arg1	environments					225:236	marine and terrestrial environments	202:236	environments	225:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	2	99	theme	polysaccharide	336:349	arg1	fucoidan					351:358	the polysaccharide fucoidan	332:358	the polysaccharide fucoidan	332:358	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	11	100	theme	temperature	1768:1778	arg1	optima					1780:1785	temperature optima	1768:1785	temperature optima	1768:1785	Fp231 is a monomeric enzyme with pH and temperature optima at pH 5.6-6.0 and 25°C, hydrolyzing Fuc(α1,4)GlcNAc with kcat = 1.3 s-1 and Km = 660 μM.					
35137077	5	101	theme	marine	1068:1073	arg1	enzymes					1080:1086	only four marine GH29 enzymes	1058:1086	only four marine GH29 enzymes	1058:1086	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	5	102	theme	several	892:898	arg1	fucosidases					905:915	several GH29 fucosidases	892:915	several GH29 fucosidases from terrestrial environments	892:945	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	4	103	theme	linkage	871:877	arg1	types					879:883	linkage types	871:883	linkage types	871:883	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	4	104	theme	hydrolase	711:719	arg1	family					721:726	glycoside hydrolase family 29	701:729	glycoside hydrolase family 29 (GH29)	701:736	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	4	104	theme	hydrolase	711:719	arg1	GH29					732:735	GH29	732:735	GH29	732:735	Fucosidases of glycoside hydrolase family 29 (GH29) release α-$\text{L} $-fucose from non-reducing ends of glycans and display activities targeting different substrate compositions and linkage types.					
35137077	2	105	theme	major	308:312	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	105	theme	major	308:312	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	0	106	theme	hydrolases	52:61	arg1	Characterization					0:15	Characterization	0:15	Characterization of five marine family 29 glycoside hydrolases	0:61	Characterization of five marine family 29 glycoside hydrolases reveals an α-L-fucosidase targeting specifically Fuc(α1,4)GlcNAc.					
35137077	5	107	theme	substrate	1030:1038	arg1	specificities					1040:1052	their substrate specificities	1024:1052	their substrate specificities	1024:1052	While several GH29 fucosidases from terrestrial environments have been characterized, much less is known about marine members of GH29 and their substrate specificities, as only four marine GH29 enzymes were previously characterized.					
35137077	2	108	from	signaling	506:514	arg1	important					488:496	important	488:496	important	488:496	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	1	109	theme	{	186:186	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	109	theme	{	186:186	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	2	110	theme	L	289:289	arg1	monosaccharide					314:327	the major monosaccharide	304:327	the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae	304:389	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	2	110	theme	L	289:289	arg1	}					290:290	$\text{L}	282:290	$\text{L} $-Fucose	282:299	$\text{L} $-Fucose is the major monosaccharide in the polysaccharide fucoidan from cell walls of brown algae and is found in human milk oligosaccharides (HMOs) and the Lewis blood group system, where it is important in cell signaling and immune response stimulation.					
35137077	1	111	theme	}	188:188	arg1	-hexose					191:197	the most widely distributed $\text{L} $-hexose	152:197	the most widely distributed $\text{L} $-hexose in marine and terrestrial environments	152:236	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
35137077	1	111	theme	}	188:188	arg1	}					137:137	$\text{L}	129:137	$\text{L} $ -Fucose	129:147	$\text{L} $ -Fucose is the most widely distributed $\text{L} $-hexose in marine and terrestrial environments and presents a variety of functional roles.					
36587649	1	0	theme	biomaterial-based	355:371	arg1	interventions					373:385	biomaterial-based interventions	355:385	biomaterial-based interventions to improve the quality of life of patients	355:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	6	1	theme	tissue	1569:1574	arg1	scaffolds					1576:1584	such tissue scaffolds	1564:1584	such tissue scaffolds	1564:1584	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	3	2	theme	spectroscopy	715:726	arg1	combination					700:710	A combination	698:710	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF)	698:911	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	1	3	theme	subchondral	167:177	arg1	bone					179:182	the subchondral bone	163:182	the subchondral bone leading to functional impairment and joint immobility	163:236	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	4	4	theme	cancellous	1051:1060	arg1	tissues					1067:1073	cancellous bone tissues	1051:1073	cancellous bone tissues	1051:1073	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	5	5	theme	MC3T3-E1	1263:1270	arg1	cells					1272:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	2	6	dep	bone	681:684	arg1	substitute					686:695	substitute	686:695	substitute	686:695	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	1	7	theme	challenging	256:266	arg1	it					243:244	it	243:244	it	243:244	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	1	7	theme	challenging	256:266	arg1	task					268:271	a very challenging task	249:271	a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients	249:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	6	8	theme	long-term	1591:1599	arg1	potential					1601:1609	long-term potential	1591:1609	long-term potential for clinical application	1591:1634	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	3	9	theme	infrared	762:769	arg1	spectroscopy					778:789	infrared (FTIR) spectroscopy	762:789	infrared (FTIR) spectroscopy	762:789	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	5	10	dep	scaffolds	1332:1340	arg1	confirmed					1345:1353	confirmed	1345:1353	confirmed by the cell attachment	1345:1376	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	2	11	theme	subchondral	669:679	arg1	bone					681:684	subchondral bone substitute	669:695	subchondral bone substitute	669:695	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	11	theme	subchondral	669:679	arg1	scaffolds					475:483	drug-/bioactive-loaded porous tissue scaffolds	438:483	drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF)	438:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	6	12	theme	such	1564:1567	arg1	scaffolds					1576:1584	such tissue scaffolds	1564:1584	such tissue scaffolds	1564:1584	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	4	13	theme	triamcinolone	1135:1147	arg1	acetonide					1149:1157	triamcinolone acetonide	1135:1157	triamcinolone acetonide	1135:1157	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	2	14	theme	hydroxypropyl	552:564	arg1	HPMC					583:586	HPMC	583:586	HPMC	583:586	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	14	theme	hydroxypropyl	552:564	arg1	methylcellulose					566:580	either hydroxypropyl methylcellulose	545:580	either hydroxypropyl methylcellulose (HPMC)	545:587	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	1	15	theme	Joint	86:90	arg1	defects					92:98	Joint defects	86:98	Joint defects associated with a variety of etiologies	86:138	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	4	16	theme	compressive	980:990	arg1	biomimetic					1037:1046	biomimetic	1037:1046	biomimetic	1037:1046	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	16	theme	compressive	980:990	arg1	properties					1003:1012	The compressive mechanical properties	976:1012	The compressive mechanical properties of these scaffolds	976:1031	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	2	17	theme	drying	652:657	arg1	method					659:664	freeze drying method	645:664	freeze drying method	645:664	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	5	18	theme	tissue	1325:1330	arg1	assay					1389:1393	live-dead assay	1379:1393	live-dead assay	1379:1393	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	5	18	theme	tissue	1325:1330	arg1	assay					1411:1415	alamarBlue™ assay	1399:1415	alamarBlue™ assay	1399:1415	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	5	18	theme	tissue	1325:1330	arg1	scaffolds					1332:1340	the tissue scaffolds	1321:1340	the tissue scaffolds as confirmed by the cell attachment	1321:1376	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	3	19	theme	scanning	792:799	arg1	SEM					822:824	SEM	822:824	SEM	822:824	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	19	theme	scanning	792:799	arg1	microscopy					810:819	scanning electron microscopy	792:819	scanning electron microscopy (SEM)	792:825	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	0	20	theme	eluting	15:21	arg1	composite					32:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite foams for osteochondral tissue engineering.					
36587649	6	21	theme	inflammatory	1483:1494	arg1	biomarkers					1496:1505	inflammatory biomarkers	1483:1505	inflammatory biomarkers	1483:1505	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	2	22	theme	freeze	645:650	arg1	method					659:664	freeze drying method	645:664	freeze drying method	645:664	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	3	23	theme	X-ray	888:892	arg1	fluorescence					894:905	X-ray fluorescence	888:905	X-ray fluorescence	888:905	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	0	24	theme	Drug/bioactive	0:13	arg1	composite					32:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite foams for osteochondral tissue engineering.					
36587649	1	25	dep	interventions	373:385	arg1	improve					390:396	improve	390:396	to improve the quality of life of patients	387:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	3	26	used	used	918:921	arg2	combination					700:710	A combination	698:710	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF)	698:911	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	6	27	theme	bone-specific	1527:1539	arg1	biomarkers					1541:1550	the bone-specific biomarkers	1523:1550	the bone-specific biomarkers	1523:1550	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	1	28	theme	functional	195:204	arg1	impairment					206:215	functional impairment	195:215	functional impairment	195:215	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	4	29	theme	scaffolds	1023:1031	arg1	biomimetic					1037:1046	biomimetic	1037:1046	biomimetic	1037:1046	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	29	theme	scaffolds	1023:1031	arg1	properties					1003:1012	The compressive mechanical properties	976:1012	The compressive mechanical properties of these scaffolds	976:1031	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	5	30	theme	alamarBlue™	1399:1409	arg1	assay					1411:1415	alamarBlue™ assay	1399:1415	alamarBlue™ assay	1399:1415	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	5	30	theme	alamarBlue™	1399:1409	arg1	scaffolds					1332:1340	the tissue scaffolds	1321:1340	the tissue scaffolds as confirmed by the cell attachment	1321:1376	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	2	31	theme	Bombyx	592:597	arg1	mori					599:602	Bombyx mori	592:602	Bombyx mori silk fibroin (SF)	592:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	32	theme	tissue	468:473	arg1	bone					681:684	subchondral bone substitute	669:695	subchondral bone substitute	669:695	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	32	theme	tissue	468:473	arg1	scaffolds					475:483	drug-/bioactive-loaded porous tissue scaffolds	438:483	drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF)	438:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	0	33	theme	chitosan	23:30	arg1	composite					32:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite	0:40	Drug/bioactive eluting chitosan composite foams for osteochondral tissue engineering.					
36587649	1	34	theme	life	413:416	arg1	quality					402:408	the quality	398:408	the quality of life of patients	398:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	3	35	dep	infrared	762:769	arg1	FTIR					772:775	FTIR	772:775	FTIR	772:775	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	2	36	theme	porous	461:466	arg1	bone					681:684	subchondral bone substitute	669:695	subchondral bone substitute	669:695	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	36	theme	porous	461:466	arg1	scaffolds					475:483	drug-/bioactive-loaded porous tissue scaffolds	438:483	drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF)	438:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	1	37	theme	bone-cartilage	291:304	arg1	interface					306:314	the bone-cartilage interface	287:314	the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients	287:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	2	38	theme	drug-/bioactive-loaded	438:459	arg1	bone					681:684	subchondral bone substitute	669:695	subchondral bone substitute	669:695	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	38	theme	drug-/bioactive-loaded	438:459	arg1	scaffolds					475:483	drug-/bioactive-loaded porous tissue scaffolds	438:483	drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF)	438:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	1	39	theme	joint	221:225	arg1	immobility					227:236	joint immobility	221:236	joint immobility	221:236	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	4	40	theme	tissues	1067:1073	arg1	biomimetic					1037:1046	biomimetic	1037:1046	biomimetic	1037:1046	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	40	theme	tissues	1067:1073	arg1	properties					1003:1012	The compressive mechanical properties	976:1012	The compressive mechanical properties of these scaffolds	976:1031	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	6	41	theme	clinical	1615:1622	arg1	application					1624:1634	clinical application	1615:1634	clinical application	1615:1634	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	1	42	theme	patients	421:428	arg1	life					413:416	life	413:416	life of patients	413:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	4	43	theme	growth	1180:1185	arg1	TGF-β1					1198:1203	TGF-β1	1198:1203	TGF-β1	1198:1203	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	43	theme	growth	1180:1185	arg1	factor-β1					1187:1195	transforming growth factor-β1	1167:1195	transforming growth factor-β1	1167:1195	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	0	44	theme	tissue	66:71	arg1	engineering					73:83	osteochondral tissue engineering	52:83	osteochondral tissue engineering	52:83	Drug/bioactive eluting chitosan composite foams for osteochondral tissue engineering.					
36587649	3	45	dep	transform	752:760	arg1	XRF					908:910	XRF	908:910	XRF	908:910	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	4	46	theme	transforming	1167:1178	arg1	TGF-β1					1198:1203	TGF-β1	1198:1203	TGF-β1	1198:1203	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	46	theme	transforming	1167:1178	arg1	factor-β1					1187:1195	transforming growth factor-β1	1167:1195	transforming growth factor-β1	1167:1195	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	0	47	theme	osteochondral	52:64	arg1	engineering					73:83	osteochondral tissue engineering	52:83	osteochondral tissue engineering	52:83	Drug/bioactive eluting chitosan composite foams for osteochondral tissue engineering.					
36587649	1	48	theme	significant	325:335	arg1	opportunities					337:349	significant opportunities	325:349	significant opportunities for biomaterial-based interventions to improve the quality of life of patients	325:428	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	6	49	contain	have	1586:1589	arg1	scaffolds					1576:1584	such tissue scaffolds	1564:1584	such tissue scaffolds	1564:1584	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	6	49	contain	have	1586:1589	arg2	potential					1601:1609	long-term potential	1591:1609	long-term potential for clinical application	1591:1634	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
36587649	1	50	theme	etiologies	129:138	arg1	etiologies					129:138	etiologies	129:138	etiologies	129:138	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	1	50	theme	etiologies	129:138	arg1	variety					118:124	a variety	116:124	a variety of etiologies	116:138	Joint defects associated with a variety of etiologies often extend deep into the subchondral bone leading to functional impairment and joint immobility, and it is a very challenging task to regenerate the bone-cartilage interface offering significant opportunities for biomaterial-based interventions to improve the quality of life of patients.					
36587649	3	51	theme	dispersive	860:869	arg1	EDX					878:880	EDX	878:880	EDX	878:880	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	51	theme	dispersive	860:869	arg1	X-ray					871:875	energy dispersive X-ray	853:875	energy dispersive X-ray (EDX)	853:881	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	52	theme	electron	801:808	arg1	SEM					822:824	SEM	822:824	SEM	822:824	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	52	theme	electron	801:808	arg1	microscopy					810:819	scanning electron microscopy	792:819	scanning electron microscopy (SEM)	792:825	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	2	53	theme	silk	604:607	arg1	SF					618:619	SF	618:619	SF	618:619	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	53	theme	silk	604:607	arg1	fibroin					609:615	Bombyx mori silk fibroin	592:615	Bombyx mori silk fibroin (SF)	592:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	4	54	theme	days	1237:1240	arg1	period					1227:1232	a period	1225:1232	a period of days	1225:1240	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	5	55	theme	live-dead	1379:1387	arg1	assay					1389:1393	live-dead assay	1379:1393	live-dead assay	1379:1393	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	5	55	theme	live-dead	1379:1387	arg1	scaffolds					1332:1340	the tissue scaffolds	1321:1340	the tissue scaffolds as confirmed by the cell attachment	1321:1376	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	4	56	theme	bone	1062:1065	arg1	tissues					1067:1073	cancellous bone tissues	1051:1073	cancellous bone tissues	1051:1073	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	2	57	theme	mori	599:602	arg1	SF					618:619	SF	618:619	SF	618:619	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	2	57	theme	mori	599:602	arg1	fibroin					609:615	Bombyx mori silk fibroin	592:615	Bombyx mori silk fibroin (SF)	592:620	Herein drug-/bioactive-loaded porous tissue scaffolds incorporating nano-hydroxyapatite (nHAp), chitosan (CS) and either hydroxypropyl methylcellulose (HPMC) or Bombyx mori silk fibroin (SF) are fabricated through freeze drying method as subchondral bone substitute.					
36587649	5	58	theme	cell	1362:1365	arg1	attachment					1367:1376	the cell attachment	1358:1376	the cell attachment	1358:1376	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	3	59	theme	porous	955:960	arg1	biomaterials					962:973	the porous biomaterials	951:973	the porous biomaterials	951:973	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	5	60	theme	Mouse	1243:1247	arg1	cells					1272:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	3	61	theme	X-ray	828:832	arg1	XRD					847:849	XRD	847:849	XRD	847:849	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	61	theme	X-ray	828:832	arg1	diffraction					834:844	X-ray diffraction	828:844	X-ray diffraction (XRD)	828:850	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	5	62	theme	preosteoblast	1249:1261	arg1	cells					1272:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells	1243:1276	Mouse preosteoblast MC3T3-E1 cells were observed to adhere and proliferate on the tissue scaffolds as confirmed by the cell attachment, live-dead assay and alamarBlue™ assay.					
36587649	3	63	theme	biomaterials	962:973	arg1	structure					938:946	the structure	934:946	the structure of the porous biomaterials	934:973	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	64	theme	energy	853:858	arg1	EDX					878:880	EDX	878:880	EDX	878:880	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	3	64	theme	energy	853:858	arg1	X-ray					871:875	energy dispersive X-ray	853:875	energy dispersive X-ray (EDX)	853:881	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	4	65	theme	mechanical	992:1001	arg1	biomimetic					1037:1046	biomimetic	1037:1046	biomimetic	1037:1046	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	4	65	theme	mechanical	992:1001	arg1	properties					1003:1012	The compressive mechanical properties	976:1012	The compressive mechanical properties of these scaffolds	976:1031	The compressive mechanical properties of these scaffolds are biomimetic of cancellous bone tissues and capable of releasing drugs/bioactives (exemplified with triamcinolone acetonide, TA, or transforming growth factor-β1, TGF-β1, respectively) over a period of days.					
36587649	3	66	theme	microscopy	732:741	arg1	combination					700:710	A combination	698:710	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF)	698:911	A combination of spectroscopy and microscopy (Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), and X-ray fluorescence (XRF) were used to analyze the structure of the porous biomaterials.					
36587649	6	67	theme	RT-qPCR	1433:1439	arg1	analysis					1441:1448	RT-qPCR analysis	1433:1448	RT-qPCR analysis	1433:1448	Interestingly, RT-qPCR analysis showed that the TA downregulated inflammatory biomarkers and upregulated the bone-specific biomarkers, suggesting such tissue scaffolds have long-term potential for clinical application.					
35469945	2	0	theme	nano-patching	473:485	arg1	strategies					488:497	"nano-patching" strategies	472:497	"nano-patching" strategies	472:497	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	3	1	theme	rGO	710:712	arg1	plane					714:718	rGO plane	710:718	rGO plane	710:718	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	2	2	theme	graphene	377:384	arg1	-NiCoFeOx					397:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	2	theme	graphene	377:384	arg1	acetate					332:338	cellulose acetate	322:338	cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	322:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	7	3	theme	electronic	1541:1550	arg1	instruments					1552:1562	electronic instruments	1541:1562	electronic instruments	1541:1562	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	0	4	theme	oxide	90:94	arg1	nanosheets					96:105	reduced graphene oxide nanosheets	73:105	reduced graphene oxide nanosheets	73:105	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	3	5	theme	defective	689:697	arg1	regions					699:705	the defective regions	685:705	the defective regions in rGO plane	685:718	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	6	6	theme	layer	1322:1326	arg1	shedding					1328:1335	obvious GO layer shedding	1311:1335	obvious GO layer shedding	1311:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	1	7	theme	bio-plastic	183:193	arg1	films					195:199	bio-plastic films	183:199	bio-plastic films	183:199	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	7	8	from	application	1487:1497	arg1	agriculture					1508:1518	agriculture	1508:1518	agriculture	1508:1518	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	8	from	application	1487:1497	arg1	pharmaceuticals					1521:1535	pharmaceuticals	1521:1535	pharmaceuticals	1521:1535	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	8	from	application	1487:1497	arg1	instruments					1552:1562	electronic instruments	1541:1562	electronic instruments	1541:1562	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	2	9	with	acetate	332:338	arg1	property					430:437	high gas barrier property	413:437	high gas barrier property	413:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	10	theme	novel	283:287	arg1	film					303:306	a novel nanocomposite film	281:306	a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	281:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	11	theme	/reduced	368:375	arg1	-NiCoFeOx					397:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	11	theme	/reduced	368:375	arg1	acetate					332:338	cellulose acetate	322:338	cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	322:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	7	12	theme	exceptional	1417:1427	arg1	film					1457:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	1	13	dep	performance	143:153	arg1	the					118:120	the	118:120	the	118:120	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	7	14	theme	barrier	1449:1455	arg1	film					1457:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	4	15	theme	moisture	895:902	arg1	rates					917:921	the oxygen and moisture transmission rates	880:921	rates	917:921	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	15	theme	moisture	895:902	arg1	result					872:877	a result	870:877	a result	870:877	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	15	theme	moisture	895:902	arg1	oxygen					884:889	the oxygen and moisture transmission rates	880:921	oxygen	884:889	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	6	16	theme	obvious	1311:1317	arg1	shedding					1328:1335	obvious GO layer shedding	1311:1335	obvious GO layer shedding	1311:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	3	17	theme	interfacial	557:567	arg1	interaction					569:579	the CA/rGO interfacial interaction	546:579	the CA/rGO interfacial interaction	546:579	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	7	18	theme	great	1471:1475	arg1	application					1487:1497	great promising application	1471:1497	great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry	1471:1581	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	1	19	theme	films	195:199	arg1	performance					143:153	gas molecule barrier performance	122:153	gas molecule barrier performance	122:153	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	1	19	theme	films	195:199	arg1	stability					170:178	structural stability	159:178	structural stability	159:178	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	7	20	theme	food	1502:1505	arg1	agriculture					1508:1518	agriculture	1508:1518	agriculture	1508:1518	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	21	theme	promising	1477:1485	arg1	application					1487:1497	great promising application	1471:1497	great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry	1471:1581	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	22	theme	packaging	1564:1572	arg1	industry					1574:1581	packaging industry	1564:1581	packaging industry	1564:1581	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	23	dep	agriculture	1508:1518	arg1	industry					1574:1581	packaging industry	1564:1581	packaging industry	1564:1581	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	6	24	theme	structural	1282:1291	arg1	stability					1293:1301	excellent structural stability	1272:1301	excellent structural stability without obvious GO layer shedding	1272:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	0	25	theme	High-performance	0:15	arg1	cellulose					17:25	High-performance cellulose	0:25	High-performance cellulose	0:25	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	6	26	theme	excellent	1272:1280	arg1	stability					1293:1301	excellent structural stability	1272:1301	excellent structural stability without obvious GO layer shedding	1272:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	1	27	theme	Improving	108:116	arg1	performance					143:153	gas molecule barrier performance	122:153	gas molecule barrier performance	122:153	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	2	28	theme	rGO	393:395	arg1	-NiCoFeOx					397:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	28	theme	rGO	393:395	arg1	acetate					332:338	cellulose acetate	322:338	cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	322:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	0	29	theme	gas	41:43	arg1	films					53:57	gas barrier films	41:57	gas barrier films	41:57	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	3	30	theme	edged	779:783	arg1	groups					814:819	edged oxygen-containing functional groups	779:819	edged oxygen-containing functional groups	779:819	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	4	31	theme	hybrid	954:959	arg1	film					961:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	7	32	theme	robust	1429:1434	arg1	film					1457:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	7	33	theme	gas	1445:1447	arg1	film					1457:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	2	34	theme	barrier	422:428	arg1	property					430:437	high gas barrier property	413:437	high gas barrier property	413:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	3	35	theme	hydrophilic	746:756	arg1	interactions					758:769	hydrophilic interactions	746:769	hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm)	746:864	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	4	36	theme	CA/PEI/rGO-NPs	939:952	arg1	film					961:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	3	37	theme	chains	646:651	arg1	role					634:637	the "molecular glue" role	613:637	the "molecular glue" role of PEI chains	613:651	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	1	38	theme	gas	122:124	arg1	performance					143:153	gas molecule barrier performance	122:153	gas molecule barrier performance	122:153	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	2	39	theme	gas	418:420	arg1	property					430:437	high gas barrier property	413:437	high gas barrier property	413:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	5	40	theme	hybrid	1157:1162	arg1	film					1164:1167	hybrid film	1157:1167	hybrid film	1157:1167	Meanwhile, the tensile strength of hybrid film was increased from 25.90 MPa to 40.67 MPa.					
35469945	6	41	contain	possesses	1262:1270	arg2	stability					1293:1301	excellent structural stability	1272:1301	excellent structural stability without obvious GO layer shedding	1272:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	6	41	contain	possesses	1262:1270	arg1	film					1257:1260	the designed nanocomposite film	1230:1260	the designed nanocomposite film	1230:1260	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	6	41	contain	possesses	1262:1270	arg2	attenuation					1356:1366	hydrophobicity attenuation	1341:1366	hydrophobicity attenuation after persistent bending	1341:1391	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	2	42	theme	high	413:416	arg1	property					430:437	high gas barrier property	413:437	high gas barrier property	413:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	4	43	theme	film	961:964	arg1	rates					917:921	the oxygen and moisture transmission rates	880:921	rates	917:921	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	43	theme	film	961:964	arg1	result					872:877	a result	870:877	a result	870:877	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	43	theme	film	961:964	arg1	oxygen					884:889	the oxygen and moisture transmission rates	880:921	oxygen	884:889	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	1	44	theme	protective	242:251	arg1	fields					253:258	protective fields	242:258	protective fields	242:258	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	0	45	theme	barrier	45:51	arg1	films					53:57	gas barrier films	41:57	gas barrier films	41:57	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	5	46	theme	film	1164:1167	arg1	strength					1145:1152	the tensile strength	1133:1152	the tensile strength of hybrid film	1133:1167	Meanwhile, the tensile strength of hybrid film was increased from 25.90 MPa to 40.67 MPa.					
35469945	5	46	theme	film	1164:1167	arg1	Meanwhile					1122:1130	Meanwhile	1122:1130	Meanwhile	1122:1130	Meanwhile, the tensile strength of hybrid film was increased from 25.90 MPa to 40.67 MPa.					
35469945	3	47	from	regions	699:705	arg1	plane					714:718	rGO plane	710:718	rGO plane	710:718	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	7	48	theme	high	1440:1443	arg1	film					1457:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film	1413:1460	The exceptional robust and high gas barrier film displays great promising application in food, agriculture, pharmaceuticals and electronic instruments packaging industry.					
35469945	2	49	theme	glue	462:465	arg1	"					466:466	"molecular glue"	451:466	"molecular glue"	451:466	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	4	50	theme	transmission	904:915	arg1	rates					917:921	the oxygen and moisture transmission rates	880:921	rates	917:921	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	50	theme	transmission	904:915	arg1	result					872:877	a result	870:877	a result	870:877	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	4	50	theme	transmission	904:915	arg1	oxygen					884:889	the oxygen and moisture transmission rates	880:921	oxygen	884:889	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	2	51	theme	"	486:486	arg1	strategies					488:497	"nano-patching" strategies	472:497	"nano-patching" strategies	472:497	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	6	52	theme	nanocomposite	1243:1255	arg1	film					1257:1260	the designed nanocomposite film	1230:1260	the designed nanocomposite film	1230:1260	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	6	53	theme	hydrophobicity	1341:1354	arg1	attenuation					1356:1366	hydrophobicity attenuation	1341:1366	hydrophobicity attenuation after persistent bending	1341:1391	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	1	54	theme	molecule	126:133	arg1	performance					143:153	gas molecule barrier performance	122:153	gas molecule barrier performance	122:153	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	2	55	theme	molecular	452:460	arg1	"					466:466	"molecular glue"	451:466	"molecular glue"	451:466	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	3	56	theme	oxygen-containing	785:801	arg1	groups					814:819	edged oxygen-containing functional groups	779:819	edged oxygen-containing functional groups	779:819	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	5	57	theme	tensile	1137:1143	arg1	strength					1145:1152	the tensile strength	1133:1152	the tensile strength of hybrid film	1133:1167	Meanwhile, the tensile strength of hybrid film was increased from 25.90 MPa to 40.67 MPa.					
35469945	5	57	theme	tensile	1137:1143	arg1	Meanwhile					1122:1130	Meanwhile	1122:1130	Meanwhile	1122:1130	Meanwhile, the tensile strength of hybrid film was increased from 25.90 MPa to 40.67 MPa.					
35469945	3	58	theme	PEI	642:644	arg1	chains					646:651	PEI chains	642:651	PEI chains	642:651	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	6	59	theme	designed	1234:1241	arg1	film					1257:1260	the designed nanocomposite film	1230:1260	the designed nanocomposite film	1230:1260	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	3	60	theme	Systematical	500:511	arg1	investigations					513:526	Systematical investigations	500:526	Systematical investigations	500:526	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	1	61	theme	barrier	135:141	arg1	performance					143:153	gas molecule barrier performance	122:153	gas molecule barrier performance	122:153	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	4	62	theme	pristine	1103:1110	arg1	films					1115:1119	pristine CA films	1103:1119	pristine CA films	1103:1119	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	3	63	theme	functional	803:812	arg1	groups					814:819	edged oxygen-containing functional groups	779:819	edged oxygen-containing functional groups	779:819	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	4	64	theme	prepared	930:937	arg1	film					961:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	the prepared CA/PEI/rGO-NPs hybrid film	926:964	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	3	65	theme	"	632:632	arg1	role					634:637	the "molecular glue" role	613:637	the "molecular glue" role of PEI chains	613:651	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	2	66	theme	nanocomposite	289:301	arg1	film					303:306	a novel nanocomposite film	281:306	a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	281:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	6	67	theme	persistent	1374:1383	arg1	bending					1385:1391	persistent bending	1374:1391	persistent bending	1374:1391	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	3	68	theme	physical/chemical	657:673	arg1	bonds					675:679	physical/chemical bonds	657:679	physical/chemical bonds	657:679	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	2	69	theme	cellulose	322:330	arg1	-NiCoFeOx					397:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	69	theme	cellulose	322:330	arg1	acetate					332:338	cellulose acetate	322:338	cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	322:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	0	70	theme	graphene	81:88	arg1	nanosheets					96:105	reduced graphene oxide nanosheets	73:105	reduced graphene oxide nanosheets	73:105	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	3	71	theme	molecular	618:626	arg1	role					634:637	the "molecular glue" role	613:637	the "molecular glue" role of PEI chains	613:651	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	1	72	theme	structural	159:168	arg1	stability					170:178	structural stability	159:178	structural stability	159:178	Improving the gas molecule barrier performance and structural stability of bio-plastic films dramatically contribute to packaging and protective fields.					
35469945	4	73	theme	CA	1112:1113	arg1	films					1115:1119	pristine CA films	1103:1119	pristine CA films	1103:1119	As a result, the oxygen and moisture transmission rates of the prepared CA/PEI/rGO-NPs hybrid film were significantly reduced to 0.31 cm3 ∗ μm/(m2 ∗ d ∗ kPa) and 314.23 g/m2 ∗ 24 h, respectively, which were 99.60% and 54.69% lower than pristine CA films.					
35469945	3	74	theme	ultrafine	825:833	arg1	nanoparticles					844:856	ultrafine NiCoFeOx nanoparticles	825:856	ultrafine NiCoFeOx nanoparticles (~3 nm)	825:864	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	3	74	theme	ultrafine	825:833	arg1	~3 nm					859:863	~3 nm	859:863	~3 nm	859:863	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	0	75	theme	reduced	73:79	arg1	nanosheets					96:105	reduced graphene oxide nanosheets	73:105	reduced graphene oxide nanosheets	73:105	High-performance cellulose acetate-based gas barrier films via tailoring reduced graphene oxide nanosheets.					
35469945	3	76	theme	CA/rGO	550:555	arg1	interaction					569:579	the CA/rGO interfacial interaction	546:579	the CA/rGO interfacial interaction	546:579	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	3	77	theme	glue	628:631	arg1	role					634:637	the "molecular glue" role	613:637	the "molecular glue" role of PEI chains	613:651	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	2	78	theme	oxide	386:390	arg1	-NiCoFeOx					397:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx	341:405	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	2	78	theme	oxide	386:390	arg1	acetate					332:338	cellulose acetate	322:338	cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property	322:437	Herein, we proposed a novel nanocomposite film consisting of cellulose acetate (CA)/polyethyleneimine (PEI)/reduced graphene oxide (rGO)-NiCoFeOx) with high gas barrier property by applying "molecular glue" and "nano-patching" strategies.					
35469945	6	79	theme	GO	1319:1320	arg1	shedding					1328:1335	obvious GO layer shedding	1311:1335	obvious GO layer shedding	1311:1335	More importantly, the designed nanocomposite film possesses excellent structural stability without obvious GO layer shedding and hydrophobicity attenuation after persistent bending at least 100 times.					
35469945	3	80	theme	NiCoFeOx	835:842	arg1	nanoparticles					844:856	ultrafine NiCoFeOx nanoparticles	825:856	ultrafine NiCoFeOx nanoparticles (~3 nm)	825:864	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35469945	3	80	theme	NiCoFeOx	835:842	arg1	~3 nm					859:863	~3 nm	859:863	~3 nm	859:863	Systematical investigations demonstrated that the CA/rGO interfacial interaction was effectively enhanced due to the "molecular glue" role of PEI chains via physical/chemical bonds and the defective regions in rGO plane were nano-patched through hydrophilic interactions between edged oxygen-containing functional groups and ultrafine NiCoFeOx nanoparticles (~3 nm).					
35882293	0	0	theme	diabetic	78:85	arg1	nephropathy					87:97	diabetic nephropathy	78:97	diabetic nephropathy	78:97	Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.					
35882293	7	1	theme	glomerular	1215:1224	arg1	damage					1226:1231	glomerular damage	1215:1231	glomerular damage	1215:1231	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	1	2	theme	common	138:143	arg1	nephropathy					109:119	Diabetic nephropathy	100:119	Diabetic nephropathy (DN)	100:124	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	1	2	theme	common	138:143	arg1	cause					145:149	the most common cause	129:149	the most common cause of end-stage renal disease	129:176	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	1	3	theme	progressive	222:232	arg1	loss					234:237	the progressive loss	218:237	the progressive loss of renal function	218:255	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	6	4	theme	SCFA-producing	1019:1032	arg1	Saccharimonas					1093:1105	Saccharimonas	1093:1105	Saccharimonas	1093:1105	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	6	4	theme	SCFA-producing	1019:1032	arg1	Akkermansia					1066:1076	Akkermansia	1066:1076	Akkermansia	1066:1076	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	6	4	theme	SCFA-producing	1019:1032	arg1	bacteria					1034:1041	SCFA-producing bacteria	1019:1041	SCFA-producing bacteria	1019:1041	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	3	5	from	effects	478:484	arg1	DN					520:521	DN	520:521	DN	520:521	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	2	6	theme	kidney	326:331	arg1	diseases					333:340	kidney diseases	326:340	kidney diseases	326:340	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	3	7	theme	inulin-type	489:499	arg1	ITFs					511:514	ITFs	511:514	ITFs	511:514	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	7	theme	inulin-type	489:499	arg1	fructans					501:508	inulin-type fructans	489:508	inulin-type fructans (ITFs)	489:515	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	4	8	theme	db/db	734:738	arg1	mice					740:743	db/db mice	734:743	db/db mice	734:743	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	0	9	theme	nephropathy	87:97	arg1	development					63:73	the development	59:73	the development of diabetic nephropathy	59:97	Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.					
35882293	1	10	theme	renal	242:246	arg1	function					248:255	renal function	242:255	renal function	242:255	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	6	11	from	changes	965:971	arg1	microbiota					984:993	the gut microbiota	976:993	the gut microbiota	976:993	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	9	12	theme	renal	1484:1488	arg1	protection					1490:1499	renal protection	1484:1499	renal protection	1484:1499	Furthermore, acetate mediates renal protection by regulating glucose metabolism, decreasing glycotoxic product levels and improving mitochondrial function.					
35882293	6	13	theme	treatment-induced	947:963	arg1	changes					965:971	The ITFs treatment-induced changes	938:971	The ITFs treatment-induced changes in the gut microbiota	938:993	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	4	14	from	damage	724:729	arg1	mice					740:743	db/db mice	734:743	db/db mice	734:743	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	6	15	theme	acetate	1144:1150	arg1	concentrations					1152:1165	the fecal and serum acetate concentrations	1124:1165	concentrations	1152:1165	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	1	16	theme	end-stage	154:162	arg1	disease					170:176	end-stage renal disease	154:176	end-stage renal disease	154:176	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	3	17	theme	fecal	614:618	arg1	transplantation					631:645	fecal microbiota transplantation	614:645	fecal microbiota transplantation (FMT)	614:651	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	17	theme	fecal	614:618	arg1	FMT					648:650	FMT	648:650	FMT	648:650	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	18	theme	fructans	501:508	arg1	effects					478:484	the protective effects	463:484	the protective effects of inulin-type fructans (ITFs) on DN	463:521	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	7	19	theme	glucose	1312:1318	arg1	levels					1331:1336	toxic glucose metabolite levels	1306:1336	toxic glucose metabolite levels	1306:1336	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	6	20	theme	ITFs	942:945	arg1	changes					965:971	The ITFs treatment-induced changes	938:971	The ITFs treatment-induced changes in the gut microbiota	938:993	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	3	21	theme	16 S	531:534	arg1	sequencing					546:555	16 S rRNA gene sequencing	531:555	16 S rRNA gene sequencing	531:555	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	1	22	theme	renal	164:168	arg1	disease					170:176	end-stage renal disease	154:176	end-stage renal disease	154:176	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	0	23	theme	Inulin-type	0:10	arg1	fructans					12:19	Inulin-type fructans	0:19	Inulin-type fructans	0:19	Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.					
35882293	1	24	theme	function	248:255	arg1	loss					234:237	the progressive loss	218:237	the progressive loss of renal function	218:255	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	4	25	theme	ITFs	678:681	arg1	supplementation					683:697	ITFs supplementation	678:697	ITFs supplementation	678:697	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	3	26	theme	rRNA	536:539	arg1	sequencing					546:555	16 S rRNA gene sequencing	531:555	16 S rRNA gene sequencing	531:555	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	6	27	theme	serum	1138:1142	arg1	concentrations					1152:1165	the fecal and serum acetate concentrations	1124:1165	concentrations	1152:1165	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	1	28	theme	disease	170:176	arg1	nephropathy					109:119	Diabetic nephropathy	100:119	Diabetic nephropathy (DN)	100:124	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	1	28	theme	disease	170:176	arg1	cause					145:149	the most common cause	129:149	the most common cause of end-stage renal disease	129:176	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	1	29	theme	Diabetic	100:107	arg1	cause					145:149	the most common cause	129:149	the most common cause of end-stage renal disease	129:176	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	1	29	theme	Diabetic	100:107	arg1	nephropathy					109:119	Diabetic nephropathy	100:119	Diabetic nephropathy (DN)	100:124	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	5	30	theme	ITFs	932:935	arg1	effects					921:927	the beneficial effects	906:927	the beneficial effects of ITFs	906:935	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	5	31	theme	beneficial	910:919	arg1	effects					921:927	the beneficial effects	906:927	the beneficial effects of ITFs	906:935	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	9	32	theme	glucose	1515:1521	arg1	metabolism					1523:1532	glucose metabolism	1515:1532	glucose metabolism	1515:1532	Furthermore, acetate mediates renal protection by regulating glucose metabolism, decreasing glycotoxic product levels and improving mitochondrial function.					
35882293	4	33	theme	kidney	717:722	arg1	damage					724:729	kidney damage	717:729	kidney damage in db/db mice	717:743	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	9	34	theme	mitochondrial	1586:1598	arg1	function					1600:1607	mitochondrial function	1586:1607	mitochondrial function	1586:1607	Furthermore, acetate mediates renal protection by regulating glucose metabolism, decreasing glycotoxic product levels and improving mitochondrial function.					
35882293	2	35	theme	fatty	407:411	arg1	SCFAs					420:424	SCFAs	420:424	SCFAs	420:424	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	2	35	theme	fatty	407:411	arg1	acids					413:417	short-chain fatty acids	395:417	short-chain fatty acids (SCFAs)	395:425	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	7	36	theme	metabolite	1320:1329	arg1	levels					1331:1336	toxic glucose metabolite levels	1306:1336	toxic glucose metabolite levels	1306:1336	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	5	37	theme	microbiota	882:891	arg1	role					866:869	a key role	860:869	a key role of the gut microbiota in mediating the beneficial effects of ITFs	860:935	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	1	38	theme	few	183:185	arg1	options					197:203	few treatment options	183:203	few treatment options that prevent the progressive loss of renal function	183:255	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	4	39	theme	gut	782:784	arg1	microbiota					786:795	the gut microbiota	778:795	the gut microbiota	778:795	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	6	40	theme	bacteria	1034:1041	arg1	enrichment					1005:1014	an enrichment	1002:1014	an enrichment	1002:1014	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35882293	2	41	theme	short-chain	395:405	arg1	SCFAs					420:424	SCFAs	420:424	SCFAs	420:424	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	2	41	theme	short-chain	395:405	arg1	acids					413:417	short-chain fatty acids	395:417	short-chain fatty acids (SCFAs)	395:425	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	0	42	theme	gut	32:34	arg1	microbiota					36:45	the gut microbiota	28:45	the gut microbiota	28:45	Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.					
35882293	3	43	theme	gas	558:560	arg1	analysis					601:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	5	44	theme	FMT	823:825	arg1	experiments					827:837	FMT experiments	823:837	FMT experiments	823:837	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	1	45	theme	treatment	187:195	arg1	options					197:203	few treatment options	183:203	few treatment options that prevent the progressive loss of renal function	183:255	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	5	46	theme	key	862:864	arg1	role					866:869	a key role	860:869	a key role of the gut microbiota in mediating the beneficial effects of ITFs	860:935	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	3	47	theme	gene	541:544	arg1	sequencing					546:555	16 S rRNA gene sequencing	531:555	16 S rRNA gene sequencing	531:555	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	5	48	theme	gut	878:880	arg1	microbiota					882:891	the gut microbiota	874:891	the gut microbiota	874:891	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	9	49	theme	product	1557:1563	arg1	levels					1565:1570	glycotoxic product levels	1546:1570	glycotoxic product levels	1546:1570	Furthermore, acetate mediates renal protection by regulating glucose metabolism, decreasing glycotoxic product levels and improving mitochondrial function.					
35882293	8	50	theme	acetate	1434:1440	arg1	production					1442:1451	acetate production	1434:1451	acetate production	1434:1451	In conclusion, ITFs play a renoprotective role by modulating the gut microbiota and increasing acetate production.					
35882293	7	51	theme	acetate	1182:1188	arg1	supplementation					1190:1204	acetate supplementation	1182:1204	acetate supplementation	1182:1204	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	4	52	theme	microbiota	786:795	arg1	composition					763:773	the composition	759:773	the composition of the gut microbiota	759:795	The results showed that ITFs supplementation protected against kidney damage in db/db mice and regulated the composition of the gut microbiota.					
35882293	3	53	theme	protective	467:476	arg1	effects					478:484	the protective effects	463:484	the protective effects of inulin-type fructans (ITFs) on DN	463:521	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	7	54	theme	mitochondrial	1267:1279	arg1	dysfunction					1281:1291	mitochondrial dysfunction	1267:1291	mitochondrial dysfunction	1267:1291	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	2	55	theme	fiber	304:308	arg1	intake					310:315	dietary fiber intake	296:315	dietary fiber intake	296:315	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	8	56	theme	gut	1404:1406	arg1	microbiota					1408:1417	the gut microbiota	1400:1417	the gut microbiota	1400:1417	In conclusion, ITFs play a renoprotective role by modulating the gut microbiota and increasing acetate production.					
35882293	8	57	theme	renoprotective	1366:1379	arg1	role					1381:1384	a renoprotective role	1364:1384	a renoprotective role	1364:1384	In conclusion, ITFs play a renoprotective role by modulating the gut microbiota and increasing acetate production.					
35882293	3	58	theme	microbiota	620:629	arg1	transplantation					631:645	fecal microbiota transplantation	614:645	fecal microbiota transplantation (FMT)	614:651	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	58	theme	microbiota	620:629	arg1	FMT					648:650	FMT	648:650	FMT	648:650	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	59	theme	GCMS	595:598	arg1	analysis					601:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	2	60	theme	dietary	296:302	arg1	intake					310:315	dietary fiber intake	296:315	dietary fiber intake	296:315	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	9	61	theme	glycotoxic	1546:1555	arg1	levels					1565:1570	glycotoxic product levels	1546:1570	glycotoxic product levels	1546:1570	Furthermore, acetate mediates renal protection by regulating glucose metabolism, decreasing glycotoxic product levels and improving mitochondrial function.					
35882293	3	62	theme	present	432:438	arg1	study					440:444	The present study	428:444	The present study	428:444	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	3	63	theme	chromatographymass	562:579	arg1	analysis					601:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	5	64	theme	Antibiotic	798:807	arg1	treatment					809:817	Antibiotic treatment	798:817	Antibiotic treatment	798:817	Antibiotic treatment and FMT experiments further demonstrated a key role of the gut microbiota in mediating the beneficial effects of ITFs.					
35882293	2	65	theme	metabolism-related	346:363	arg1	diseases					365:372	metabolism-related diseases	346:372	metabolism-related diseases	346:372	Studies have shown that dietary fiber intake improves kidney diseases and metabolism-related diseases, most likely through short-chain fatty acids (SCFAs).					
35882293	7	66	theme	renal	1237:1241	arg1	fibrosis					1243:1250	renal fibrosis	1237:1250	renal fibrosis	1237:1250	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	3	67	theme	spectrometry	581:592	arg1	analysis					601:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	gas chromatographymass spectrometry (GCMS) analysis	558:608	The present study aimed to examine the protective effects of inulin-type fructans (ITFs) on DN through 16 S rRNA gene sequencing, gas chromatographymass spectrometry (GCMS) analysis and fecal microbiota transplantation (FMT).					
35882293	1	68	dep	nephropathy	109:119	arg1	DN					122:123	DN	122:123	DN	122:123	Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available.					
35882293	7	69	theme	toxic	1306:1310	arg1	levels					1331:1336	toxic glucose metabolite levels	1306:1336	toxic glucose metabolite levels	1306:1336	Subsequently, acetate supplementation improved glomerular damage and renal fibrosis by attenuating mitochondrial dysfunction and reducing toxic glucose metabolite levels.					
35882293	6	70	theme	gut	980:982	arg1	microbiota					984:993	the gut microbiota	976:993	the gut microbiota	976:993	The ITFs treatment-induced changes in the gut microbiota led to an enrichment of SCFA-producing bacteria, especially the genera Akkermansia and Candidatus Saccharimonas, which increased the fecal and serum acetate concentrations.					
35037458	13	0	theme	biodegradation	2672:2685	arg1	potential					2687:2695	the biodegradation potential	2668:2695	the biodegradation potential of the composite scaffold	2668:2721	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	3	1	from	desirable	536:544	arg1	healing					555:561	wound healing	549:561	wound healing	549:561	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	2	2	theme	targeted	379:386	arg1	proliferation					393:405	targeted cell proliferation	379:405	targeted cell proliferation	379:405	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	13	3	theme	weight	2560:2565	arg1	%					2579:2579	80 ± 5%	2573:2579	80 ± 5%	2573:2579	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	13	3	theme	weight	2560:2565	arg1	loss					2567:2570	significant weight loss	2548:2570	significant weight loss (80 ± 5%)	2548:2580	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	4	theme	swelling	1620:1627	arg1	behavior					1629:1636	a better swelling behavior	1611:1636	a better swelling behavior	1611:1636	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	12	5	theme	3D	2348:2349	arg1	scaffold					2361:2368	the 3D composite scaffold	2344:2368	the 3D composite scaffold	2344:2368	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	10	6	theme	blood	1888:1892	arg1	clot					1894:1897	stable blood clot	1881:1897	stable blood clot	1881:1897	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	3	7	theme	desirable	536:544	arg1	scaffolds					526:534	specific 3D scaffolds	514:534	specific 3D scaffolds desirable in wound healing	514:561	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	13	8	theme	incubation	2645:2654	arg1	days					2637:2640	28 days	2634:2640	28 days of incubation	2634:2654	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	2	9	from	activity	366:373	arg1	healing					437:443	rapid and controlled wound healing	410:443	rapid and controlled wound healing	410:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	13	10	theme	composite	2522:2530	arg1	scaffold					2532:2539	the 3D composite scaffold	2515:2539	the 3D composite scaffold	2515:2539	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	11	theme	faster	1644:1649	arg1	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	13	12	theme	in	2488:2489	arg1	deconstruction					2497:2510	Cellulase-based in vitro deconstruction	2472:2510	Cellulase-based in vitro deconstruction of the 3D composite scaffold	2472:2539	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	13	theme	blood	1657:1661	arg1	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	2	14	from	proliferation	393:405	arg1	healing					437:443	rapid and controlled wound healing	410:443	rapid and controlled wound healing	410:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	10	15	theme	faster	2029:2034	arg1	coagulation					2042:2052	faster blood coagulation	2029:2052	faster blood coagulation	2029:2052	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	2	16	theme	desired	315:321	arg1	complexity					334:343	the desired structural complexity	311:343	the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing	311:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	6	17	theme	complexation	1078:1089	arg1	approach					1091:1098	a green ionic complexation approach	1064:1098	a green ionic complexation approach	1064:1098	Further, the 3D composite scaffolds were in situ cross-linked using a green ionic complexation approach.					
35037458	4	18	theme	cellulose	684:692	arg1	TCNFs					707:711	TCNFs	707:711	TCNFs	707:711	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	4	18	theme	cellulose	684:692	arg1	nanofibrils					694:704	cellulose nanofibrils	684:704	cellulose nanofibrils (TCNFs)	684:712	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	10	19	theme	TAT	1768:1770	arg1	assay					1772:1776	The TAT assay	1764:1776	The TAT assay	1764:1776	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	5	20	theme	±	865:865	arg1	content					848:854	a casein content	839:854	a casein content of 104.5 ±	839:865	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	8	21	theme	3D	1445:1446	arg1	scaffold					1458:1465	the 3D composite scaffold	1441:1465	the 3D composite scaffold	1441:1465	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	7	22	theme	X-ray	1372:1376	arg1	diffraction					1378:1388	X-ray diffraction	1372:1388	X-ray diffraction (XRD)	1372:1394	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	22	theme	X-ray	1372:1376	arg1	XRD					1391:1393	XRD	1391:1393	XRD	1391:1393	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	12	23	theme	wound	2457:2461	arg1	healing					2463:2469	wound healing	2457:2469	wound healing	2457:2469	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	14	24	theme	efficient	2759:2767	arg1	prospects					2769:2777	efficient prospects	2759:2777	efficient prospects	2759:2777	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	8	25	theme	scaffold	1458:1465	arg1	activity					1429:1436	The in vitro hemostasis activity	1405:1436	The in vitro hemostasis activity of the 3D composite scaffold	1405:1465	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	4	26	theme	blood	747:751	arg1	loss					753:756	blood loss	747:756	blood loss	747:756	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	10	27	theme	3D	1944:1945	arg1	TCNF					1947:1950	3D TCNF	1944:1950	3D TCNF (457.78 pg/mL)	1944:1965	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	10	27	theme	3D	1944:1945	arg1	pg/mL					1960:1964	457.78 pg/mL	1953:1964	457.78 pg/mL	1953:1964	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	4	28	dep	technology	632:641	arg1	mechanisms					670:679	mechanisms	670:679	mechanisms	670:679	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	8	29	dep	in	1409:1410	arg1	vitro					1412:1416	vitro	1412:1416	vitro	1412:1416	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	6	30	theme	ionic	1072:1076	arg1	approach					1091:1098	a green ionic complexation approach	1064:1098	a green ionic complexation approach	1064:1098	Further, the 3D composite scaffolds were in situ cross-linked using a green ionic complexation approach.					
35037458	14	31	theme	bioinks	2845:2851	arg1	bioprinting					2819:2829	bioprinting	2819:2829	bioprinting of TCNF-based bioinks	2819:2851	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	5	32	theme	casein	841:846	arg1	content					848:854	a casein content	839:854	a casein content of 104.5 ±	839:865	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	5	33	theme	carbodiimide	888:899	arg1	chemistry					914:922	the carbodiimide cross-linker chemistry	884:922	the carbodiimide cross-linker chemistry	884:922	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	9	34	theme	TCNF	1708:1711	arg1	scaffold					1713:1720	the 3D TCNF scaffold	1701:1720	the 3D TCNF scaffold	1701:1720	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	4	35	theme	composite	583:591	arg1	scaffold					593:600	a 3D composite scaffold	578:600	a 3D composite scaffold	578:600	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	7	36	dep	Fourier	1176:1182	arg1	transform					1184:1192	transform	1184:1192	transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies	1184:1402	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	0	37	theme	Wound-Healing	96:108	arg1	Application					110:120	Potential Wound-Healing Application	86:120	Potential Wound-Healing Application	86:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	12	38	dep	in	2252:2253	arg1	vivo					2255:2258	vivo	2255:2258	vivo	2255:2258	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	1	39	theme	natural	193:199	arg1	healing					207:213	natural wound healing	193:213	natural wound healing	193:213	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	12	40	theme	cells	2431:2435	arg1	proliferation					2395:2407	proliferation	2395:2407	proliferation	2395:2407	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	12	40	theme	cells	2431:2435	arg1	growth					2384:2389	growth	2384:2389	growth	2384:2389	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	6	41	theme	composite	1012:1020	arg1	scaffolds					1022:1030	the 3D composite scaffolds	1005:1030	the 3D composite scaffolds	1005:1030	Further, the 3D composite scaffolds were in situ cross-linked using a green ionic complexation approach.					
35037458	8	42	theme	thrombin-antithrombin	1491:1511	arg1	assay					1519:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	7	43	dep	infrared	1194:1201	arg1	FTIR					1204:1207	FTIR	1204:1207	FTIR	1204:1207	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	12	44	theme	3T3	2416:2418	arg1	cells					2431:2435	NIH 3T3 fibroblast cells	2412:2435	NIH 3T3 fibroblast cells	2412:2435	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	9	45	theme	cellulose-based	1737:1751	arg1	dressings					1753:1761	commercial cellulose-based dressings	1726:1761	commercial cellulose-based dressings	1726:1761	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	8	46	theme	TAT	1514:1516	arg1	assay					1519:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	7	47	theme	dodecyl	1305:1311	arg1	SDS-PAGE					1357:1364	SDS-PAGE	1357:1364	SDS-PAGE	1357:1364	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	47	theme	dodecyl	1305:1311	arg1	electrophoresis					1340:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis	1298:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)	1298:1365	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	2	48	theme	wound	431:435	arg1	healing					437:443	rapid and controlled wound healing	410:443	rapid and controlled wound healing	410:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	14	49	theme	composite	2795:2803	arg1	scaffold					2805:2812	a 3D composite scaffold	2790:2812	a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage	2790:2993	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	8	50	theme	red	1543:1545	arg1	RBCs					1560:1563	RBCs	1560:1563	RBCs	1560:1563	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	8	50	theme	red	1543:1545	arg1	cells					1553:1557	red blood cells	1543:1557	red blood cells (RBCs)	1543:1564	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	11	51	contain	had	2094:2096	arg1	scaffold					2085:2092	the 3D composite scaffold	2068:2092	the 3D composite scaffold	2068:2092	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	51	contain	had	2094:2096	arg2	index					2121:2125	a lower blood clotting index	2098:2125	a lower blood clotting index (23.34%)	2098:2134	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	51	contain	had	2094:2096	arg2	%					2133:2133	23.34%	2128:2133	23.34%	2128:2133	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	14	52	theme	traumatic	2974:2982	arg1	hemorrhage					2984:2993	traumatic hemorrhage	2974:2993	traumatic hemorrhage	2974:2993	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	5	53	theme	customizable	958:969	arg1	fabrication					983:993	customizable 3D scaffold fabrication	958:993	customizable 3D scaffold fabrication	958:993	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	7	54	theme	gel	1336:1338	arg1	SDS-PAGE					1357:1364	SDS-PAGE	1357:1364	SDS-PAGE	1357:1364	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	54	theme	gel	1336:1338	arg1	electrophoresis					1340:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis	1298:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)	1298:1365	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	11	55	theme	blood	2232:2236	arg1	clotting					2238:2245	blood clotting	2232:2245	blood clotting	2232:2245	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	0	56	theme	Cellulose	15:23	arg1	Scaffold					73:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold	15:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application	15:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	5	57	theme	scaffold	974:981	arg1	fabrication					983:993	customizable 3D scaffold fabrication	958:993	customizable 3D scaffold fabrication	958:993	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	6	58	theme	green	1066:1070	arg1	approach					1091:1098	a green ionic complexation approach	1064:1098	a green ionic complexation approach	1064:1098	Further, the 3D composite scaffolds were in situ cross-linked using a green ionic complexation approach.					
35037458	11	59	theme	3D	2072:2073	arg1	scaffold					2085:2092	the 3D composite scaffold	2068:2092	the 3D composite scaffold	2068:2092	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	4	60	theme	3D	580:581	arg1	scaffold					593:600	a 3D composite scaffold	578:600	a 3D composite scaffold	578:600	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	0	61	theme	3D	49:50	arg1	Scaffold					73:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold	15:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application	15:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	5	62	theme	casein	807:812	arg1	mg/g					872:875	34.1 mg/g	867:875	34.1 mg/g	867:875	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	5	62	theme	casein	807:812	arg1	TCNF					828:831	casein bioconjugated TCNF	807:831	casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry	807:922	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	8	63	theme	cells	1553:1557	arg1	adsorption					1529:1538	adsorption	1529:1538	adsorption of red blood cells (RBCs) and platelets	1529:1578	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	8	63	theme	cells	1553:1557	arg1	assay					1519:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	10	64	theme	composite	1803:1811	arg1	scaffold					1813:1820	the 3D composite scaffold	1796:1820	the 3D composite scaffold	1796:1820	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	3	65	theme	3D	523:524	arg1	scaffolds					526:534	specific 3D scaffolds	514:534	specific 3D scaffolds desirable in wound healing	514:561	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	0	66	theme	Hemostasis	62:71	arg1	Scaffold					73:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold	15:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application	15:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	11	67	theme	lower	2100:2104	arg1	index					2121:2125	a lower blood clotting index	2098:2125	a lower blood clotting index (23.34%)	2098:2134	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	67	theme	lower	2100:2104	arg1	%					2133:2133	23.34%	2128:2133	23.34%	2128:2133	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	10	68	theme	cellulosic	1972:1981	arg1	gauze					1983:1987	cellulosic gauze	1972:1987	cellulosic gauze (328.92 pg/mL)	1972:2002	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	10	68	theme	cellulosic	1972:1981	arg1	pg/mL					1997:2001	328.92 pg/mL	1990:2001	328.92 pg/mL	1990:2001	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	7	69	dep	spectroscopy	1210:1221	arg1	studies					1396:1402	studies	1396:1402	studies	1396:1402	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	2	70	theme	hemostasis	355:364	arg1	activity					366:373	hemostasis activity	355:373	hemostasis activity	355:373	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	14	71	theme	blood	2956:2960	arg1	loss					2962:2965	blood loss	2956:2965	blood loss	2956:2965	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	13	72	theme	scaffold	2714:2721	arg1	potential					2687:2695	the biodegradation potential	2668:2695	the biodegradation potential of the composite scaffold	2668:2721	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	73	theme	composite	1588:1596	arg1	scaffold					1598:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	14	74	theme	potential	2922:2930	arg1	application					2932:2942	its potential application	2918:2942	its potential application in reducing blood loss during traumatic hemorrhage	2918:2993	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	4	75	theme	bioprinting	620:630	arg1	technology					632:641	bioprinting technology	620:641	bioprinting technology	620:641	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	11	76	theme	3D	2145:2146	arg1	%					2168:2168	41.93%	2163:2168	41.93%	2163:2168	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	76	theme	3D	2145:2146	arg1	scaffold					2153:2160	the 3D TCNF scaffold	2141:2160	the 3D TCNF scaffold (41.93%)	2141:2169	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	3	77	theme	wound	549:553	arg1	healing					555:561	wound healing	549:561	wound healing	549:561	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	11	78	theme	blood	2106:2110	arg1	index					2121:2125	a lower blood clotting index	2098:2125	a lower blood clotting index (23.34%)	2098:2134	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	78	theme	blood	2106:2110	arg1	%					2133:2133	23.34%	2128:2133	23.34%	2128:2133	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	5	79	theme	bioconjugated	814:826	arg1	mg/g					872:875	34.1 mg/g	867:875	34.1 mg/g	867:875	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	5	79	theme	bioconjugated	814:826	arg1	TCNF					828:831	casein bioconjugated TCNF	807:831	casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry	807:922	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	7	80	theme	X-ray	1258:1262	arg1	spectroscopy					1278:1289	X-ray photoelectron spectroscopy	1258:1289	X-ray photoelectron spectroscopy (XPS)	1258:1295	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	80	theme	X-ray	1258:1262	arg1	XPS					1292:1294	XPS	1292:1294	XPS	1292:1294	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	11	81	theme	higher	2183:2188	arg1	efficiencies					2190:2201	higher efficiencies	2183:2201	higher efficiencies for RBC entrapping to induce blood clotting	2183:2245	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	14	82	theme	TCNF-based	2834:2843	arg1	bioinks					2845:2851	TCNF-based bioinks	2834:2851	TCNF-based bioinks	2834:2851	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	2	83	theme	cell	388:391	arg1	proliferation					393:405	targeted cell proliferation	379:405	targeted cell proliferation	379:405	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	13	84	theme	significant	2548:2558	arg1	%					2579:2579	80 ± 5%	2573:2579	80 ± 5%	2573:2579	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	13	84	theme	significant	2548:2558	arg1	loss					2567:2570	significant weight loss	2548:2570	significant weight loss (80 ± 5%)	2548:2580	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	85	theme	better	1613:1618	arg1	behavior					1629:1636	a better swelling behavior	1611:1636	a better swelling behavior	1611:1636	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	12	86	theme	composite	2351:2359	arg1	scaffold					2361:2368	the 3D composite scaffold	2344:2368	the 3D composite scaffold	2344:2368	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	10	87	theme	thrombin	1853:1860	arg1	content					1842:1848	a higher content	1833:1848	a higher content of thrombin (663.29 pg/mL) and stable blood clot	1833:1897	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	14	88	from	bioprinting	2819:2829	arg1	scaffold					2805:2812	a 3D composite scaffold	2790:2812	a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage	2790:2993	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	10	89	theme	stable	1881:1886	arg1	clot					1894:1897	stable blood clot	1881:1897	stable blood clot	1881:1897	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	3	90	from	healing	555:561	arg1	desirable					536:544	desirable	536:544	desirable	536:544	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	2	91	theme	bioinks	296:302	arg1	bioprinting					281:291	The three-dimensional (3D) bioprinting	254:291	The three-dimensional (3D) bioprinting of bioinks	254:302	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	13	92	theme	3D	2519:2520	arg1	scaffold					2532:2539	the 3D composite scaffold	2515:2539	the 3D composite scaffold	2515:2539	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	1	93	theme	wound	201:205	arg1	healing					207:213	natural wound healing	193:213	natural wound healing	193:213	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	4	94	theme	nanofibrils	694:704	arg1	technology					632:641	bioprinting technology	620:641	bioprinting technology	620:641	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	4	94	theme	nanofibrils	694:704	arg1	hemostasis					659:668	synergistic hemostasis	647:668	synergistic hemostasis	647:668	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	4	94	theme	nanofibrils	694:704	arg1	chitosan					715:722	chitosan	715:722	chitosan	715:722	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	4	94	theme	nanofibrils	694:704	arg1	casein					729:734	casein	729:734	casein	729:734	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	7	95	theme	magnetic	1232:1239	arg1	NMR					1252:1254	NMR	1252:1254	NMR	1252:1254	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	95	theme	magnetic	1232:1239	arg1	resonance					1241:1249	nuclear magnetic resonance	1224:1249	nuclear magnetic resonance (NMR)	1224:1255	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	96	theme	covalent	1105:1112	arg1	conjugation					1114:1124	The covalent conjugation	1101:1124	The covalent conjugation among TCNF, casein, and chitosan	1101:1157	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	2	97	theme	vital	345:349	arg1	complexity					334:343	the desired structural complexity	311:343	the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing	311:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	13	98	theme	scaffold	2532:2539	arg1	deconstruction					2497:2510	Cellulase-based in vitro deconstruction	2472:2510	Cellulase-based in vitro deconstruction of the 3D composite scaffold	2472:2539	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	99	theme	whole	1651:1655	arg1	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	10	100	theme	blood	2036:2040	arg1	coagulation					2042:2052	faster blood coagulation	2029:2052	faster blood coagulation	2029:2052	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	2	101	theme	structural	323:332	arg1	complexity					334:343	the desired structural complexity	311:343	the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing	311:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	14	102	theme	blood	2873:2877	arg1	clotting					2879:2886	blood clotting	2873:2886	blood clotting	2873:2886	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	1	103	theme	main	223:226	arg1	reason					228:233	the main reason	219:233	the main reason for trauma deaths	219:251	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	9	104	theme	clotting	1663:1670	arg1	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	11	105	theme	TCNF	2148:2151	arg1	%					2168:2168	41.93%	2163:2168	41.93%	2163:2168	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	105	theme	TCNF	2148:2151	arg1	scaffold					2153:2160	the 3D TCNF scaffold	2141:2160	the 3D TCNF scaffold (41.93%)	2141:2169	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	9	106	contain	had	1607:1609	arg2	behavior					1629:1636	a better swelling behavior	1611:1636	a better swelling behavior	1611:1636	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	9	106	contain	had	1607:1609	arg1	scaffold					1598:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	9	106	contain	had	1607:1609	arg2	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	10	107	theme	clot	1894:1897	arg1	content					1842:1848	a higher content	1833:1848	a higher content of thrombin (663.29 pg/mL) and stable blood clot	1833:1897	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	2	108	theme	three-dimensional	258:274	arg1	bioprinting					281:291	The three-dimensional (3D) bioprinting	254:291	The three-dimensional (3D) bioprinting of bioinks	254:302	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	8	109	theme	composite	1448:1456	arg1	scaffold					1458:1465	the 3D composite scaffold	1441:1465	the 3D composite scaffold	1441:1465	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	12	110	theme	culture	2305:2311	arg1	study					2313:2317	a 3D cell culture study	2295:2317	a 3D cell culture study	2295:2317	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	1	111	theme	traumatic	145:153	arg1	hemorrhage					155:164	traumatic hemorrhage	145:164	traumatic hemorrhage	145:164	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	9	112	theme	time	1685:1688	arg1	point					1690:1694	each time point	1680:1694	each time point	1680:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	10	113	theme	cellulosic	1913:1922	arg1	pad					1924:1926	a cellulosic pad	1911:1926	a cellulosic pad (580.35 pg/mL)	1911:1941	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	10	113	theme	cellulosic	1913:1922	arg1	pg/mL					1936:1940	580.35 pg/mL	1929:1940	580.35 pg/mL	1929:1940	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	10	113	theme	cellulosic	1913:1922	arg1	essential					2015:2023	essential	2015:2023	essential	2015:2023	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	10	114	theme	3D	1800:1801	arg1	scaffold					1813:1820	the 3D composite scaffold	1796:1820	the 3D composite scaffold	1796:1820	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	9	115	from	point	1690:1694	arg1	rate					1672:1675	a faster whole blood clotting rate	1642:1675	a faster whole blood clotting rate at each time point	1642:1694	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	9	115	from	point	1690:1694	arg1	behavior					1629:1636	a better swelling behavior	1611:1636	a better swelling behavior	1611:1636	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	12	116	theme	3D	2297:2298	arg1	study					2313:2317	a 3D cell culture study	2295:2317	a 3D cell culture study	2295:2317	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	0	117	theme	Potential	86:94	arg1	Application					110:120	Potential Wound-Healing Application	86:120	Potential Wound-Healing Application	86:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	13	118	theme	±	2622:2622	arg1	%					2625:2625	22 ± 5%	2619:2625	22 ± 5%	2619:2625	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	13	118	theme	±	2622:2622	arg1	hydrolysis					2607:2616	the lysozyme hydrolysis	2594:2616	the lysozyme hydrolysis (22 ± 5%)	2594:2626	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	1	119	theme	primary	173:179	arg1	concern					181:187	the primary concern	169:187	the primary concern for natural wound healing	169:213	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	1	119	theme	primary	173:179	arg1	bleeding					133:140	bleeding	133:140	bleeding	133:140	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	9	120	theme	3D	1705:1706	arg1	scaffold					1713:1720	the 3D TCNF scaffold	1701:1720	the 3D TCNF scaffold	1701:1720	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	8	121	theme	human	1485:1489	arg1	assay					1519:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	13	122	dep	in	2488:2489	arg1	vitro					2491:2495	vitro	2491:2495	vitro	2491:2495	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	7	123	theme	nuclear	1224:1230	arg1	NMR					1252:1254	NMR	1252:1254	NMR	1252:1254	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	123	theme	nuclear	1224:1230	arg1	resonance					1241:1249	nuclear magnetic resonance	1224:1249	nuclear magnetic resonance (NMR)	1224:1255	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	12	124	theme	cell	2300:2303	arg1	study					2313:2317	a 3D cell culture study	2295:2317	a 3D cell culture study	2295:2317	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	5	125	theme	cross-linker	901:912	arg1	chemistry					914:922	the carbodiimide cross-linker chemistry	884:922	the carbodiimide cross-linker chemistry	884:922	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	12	126	theme	fibroblast	2420:2429	arg1	cells					2431:2435	NIH 3T3 fibroblast cells	2412:2435	NIH 3T3 fibroblast cells	2412:2435	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	13	127	theme	lysozyme	2598:2605	arg1	%					2625:2625	22 ± 5%	2619:2625	22 ± 5%	2619:2625	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	13	127	theme	lysozyme	2598:2605	arg1	hydrolysis					2607:2616	the lysozyme hydrolysis	2594:2616	the lysozyme hydrolysis (22 ± 5%)	2594:2626	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	128	theme	commercial	1726:1735	arg1	dressings					1753:1761	commercial cellulose-based dressings	1726:1761	commercial cellulose-based dressings	1726:1761	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	11	129	theme	clotting	2112:2119	arg1	index					2121:2125	a lower blood clotting index	2098:2125	a lower blood clotting index (23.34%)	2098:2134	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	11	129	theme	clotting	2112:2119	arg1	%					2133:2133	23.34%	2128:2133	23.34%	2128:2133	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	2	130	theme	controlled	420:429	arg1	healing					437:443	rapid and controlled wound healing	410:443	rapid and controlled wound healing	410:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	7	131	theme	infrared	1194:1201	arg1	spectroscopy					1210:1221	infrared (FTIR) spectroscopy	1194:1221	infrared (FTIR) spectroscopy	1194:1221	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	13	132	theme	Cellulase-based	2472:2486	arg1	deconstruction					2497:2510	Cellulase-based in vitro deconstruction	2472:2510	Cellulase-based in vitro deconstruction of the 3D composite scaffold	2472:2539	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	7	133	theme	sulfate-polyacrylamide	1313:1334	arg1	SDS-PAGE					1357:1364	SDS-PAGE	1357:1364	SDS-PAGE	1357:1364	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	133	theme	sulfate-polyacrylamide	1313:1334	arg1	electrophoresis					1340:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis	1298:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)	1298:1365	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	12	134	theme	NIH	2412:2414	arg1	cells					2431:2435	NIH 3T3 fibroblast cells	2412:2435	NIH 3T3 fibroblast cells	2412:2435	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	2	135	theme	rapid	410:414	arg1	healing					437:443	rapid and controlled wound healing	410:443	rapid and controlled wound healing	410:443	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	0	136	theme	Nanofibril/Casein-Based	25:47	arg1	Scaffold					73:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold	15:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application	15:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	1	137	from	hemorrhage	155:164	arg1	concern					181:187	the primary concern	169:187	the primary concern for natural wound healing	169:213	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	1	137	from	hemorrhage	155:164	arg1	bleeding					133:140	bleeding	133:140	bleeding	133:140	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	5	138	theme	3D	971:972	arg1	fabrication					983:993	customizable 3D scaffold fabrication	958:993	customizable 3D scaffold fabrication	958:993	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	7	139	theme	sodium	1298:1303	arg1	SDS-PAGE					1357:1364	SDS-PAGE	1357:1364	SDS-PAGE	1357:1364	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	139	theme	sodium	1298:1303	arg1	electrophoresis					1340:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis	1298:1354	sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)	1298:1365	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	8	140	theme	blood	1547:1551	arg1	RBCs					1560:1563	RBCs	1560:1563	RBCs	1560:1563	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	8	140	theme	blood	1547:1551	arg1	cells					1553:1557	red blood cells	1543:1557	red blood cells (RBCs)	1543:1564	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	4	141	theme	traumatic	761:769	arg1	hemorrhage					771:780	traumatic hemorrhage	761:780	traumatic hemorrhage	761:780	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	14	142	theme	wound	2892:2896	arg1	healing					2898:2904	wound healing	2892:2904	wound healing	2892:2904	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
35037458	0	143	theme	Composite	52:60	arg1	Scaffold					73:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold	15:80	Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application	15:120	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	2	144	dep	three-dimensional	258:274	arg1	3D					277:278	3D	277:278	3D	277:278	The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity and targeted cell proliferation in rapid and controlled wound healing.					
35037458	11	145	theme	composite	2075:2083	arg1	scaffold					2085:2092	the 3D composite scaffold	2068:2092	the 3D composite scaffold	2068:2092	In addition, the 3D composite scaffold had a lower blood clotting index (23.34%) than the 3D TCNF scaffold (41.93%), suggesting higher efficiencies for RBC entrapping to induce blood clotting.					
35037458	12	146	theme	in	2252:2253	arg1	cytocompatibility					2260:2276	The in vivo cytocompatibility	2248:2276	The in vivo cytocompatibility	2248:2276	The in vivo cytocompatibility was evaluated by a 3D cell culture study, and results showed that the 3D composite scaffold could promote growth and proliferation of NIH 3T3 fibroblast cells, which is vital for wound healing.					
35037458	3	147	theme	suitable	484:491	arg1	bioinks					493:499	suitable bioinks	484:499	suitable bioinks	484:499	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	0	148	theme	Scaffold	73:80	arg1	Development					0:10	Development	0:10	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.	0:121	Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.					
35037458	1	149	from	bleeding	133:140	arg1	hemorrhage					155:164	traumatic hemorrhage	145:164	traumatic hemorrhage	145:164	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	13	150	theme	composite	2704:2712	arg1	scaffold					2714:2721	the composite scaffold	2700:2721	the composite scaffold	2700:2721	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	9	151	theme	3D	1585:1586	arg1	scaffold					1598:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold	1581:1605	The 3D composite scaffold had a better swelling behavior and a faster whole blood clotting rate at each time point than the 3D TCNF scaffold and commercial cellulose-based dressings.					
35037458	7	152	theme	photoelectron	1264:1276	arg1	spectroscopy					1278:1289	X-ray photoelectron spectroscopy	1258:1289	X-ray photoelectron spectroscopy (XPS)	1258:1295	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	7	152	theme	photoelectron	1264:1276	arg1	XPS					1292:1294	XPS	1292:1294	XPS	1292:1294	The covalent conjugation among TCNF, casein, and chitosan was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and X-ray diffraction (XRD) studies.					
35037458	8	153	theme	platelets	1570:1578	arg1	adsorption					1529:1538	adsorption	1529:1538	adsorption of red blood cells (RBCs) and platelets	1529:1578	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	8	153	theme	platelets	1570:1578	arg1	assay					1519:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	a human thrombin-antithrombin (TAT) assay	1483:1523	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	5	154	with	mg/g	872:875	arg1	content					848:854	a casein content	839:854	a casein content of 104.5 ±	839:865	Bioinks that consist of casein bioconjugated TCNF (with a casein content of 104.5 ± 34.1 mg/g) using the carbodiimide cross-linker chemistry were subjected to bioprinting for customizable 3D scaffold fabrication.					
35037458	10	155	theme	higher	1835:1840	arg1	content					1842:1848	a higher content	1833:1848	a higher content of thrombin (663.29 pg/mL) and stable blood clot	1833:1897	The TAT assay demonstrated that the 3D composite scaffold could form a higher content of thrombin (663.29 pg/mL) and stable blood clot compared to a cellulosic pad (580.35 pg/mL), 3D TCNF (457.78 pg/mL), and cellulosic gauze (328.92 pg/mL), which are essential for faster blood coagulation.					
35037458	8	156	theme	in	1409:1410	arg1	activity					1429:1436	The in vitro hemostasis activity	1405:1436	The in vitro hemostasis activity of the 3D composite scaffold	1405:1465	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	3	157	theme	specific	514:521	arg1	scaffolds					526:534	specific 3D scaffolds	514:534	specific 3D scaffolds desirable in wound healing	514:561	However, it is challenging to develop suitable bioinks to fabricate specific 3D scaffolds desirable in wound healing.					
35037458	13	158	theme	±	2576:2576	arg1	%					2579:2579	80 ± 5%	2573:2579	80 ± 5%	2573:2579	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	13	158	theme	±	2576:2576	arg1	loss					2567:2570	significant weight loss	2548:2570	significant weight loss (80 ± 5%)	2548:2580	Cellulase-based in vitro deconstruction of the 3D composite scaffold showed significant weight loss (80 ± 5%) compared to the lysozyme hydrolysis (22 ± 5%) after 28 days of incubation, suggesting the biodegradation potential of the composite scaffold.					
35037458	1	159	theme	trauma	239:244	arg1	deaths					246:251	trauma deaths	239:251	trauma deaths	239:251	Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths.					
35037458	4	160	theme	synergistic	647:657	arg1	hemostasis					659:668	synergistic hemostasis	647:668	synergistic hemostasis	647:668	In this work, a 3D composite scaffold is designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage.					
35037458	8	161	theme	hemostasis	1418:1427	arg1	activity					1429:1436	The in vitro hemostasis activity	1405:1436	The in vitro hemostasis activity of the 3D composite scaffold	1405:1465	The in vitro hemostasis activity of the 3D composite scaffold was analyzed by a human thrombin-antithrombin (TAT) assay and adsorption of red blood cells (RBCs) and platelets.					
35037458	14	162	theme	3D	2792:2793	arg1	scaffold					2805:2812	a 3D composite scaffold	2790:2812	a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage	2790:2993	In conclusion, this study proposes efficient prospects to develop a 3D composite scaffold from bioprinting of TCNF-based bioinks that can accelerate blood clotting and wound healing, suggesting its potential application in reducing blood loss during traumatic hemorrhage.					
36270403	0	0	theme	gut	100:102	arg1	microbiota					104:113	gut microbiota	100:113	gut microbiota in LPS-challenged laying hens	100:143	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	8	1	theme	laying	1536:1541	arg1	hens					1543:1546	laying hens	1536:1546	laying hens	1536:1546	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	8	2	from	prebiotics	1505:1514	arg1	hens					1543:1546	laying hens	1536:1546	laying hens	1536:1546	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	6	3	theme	β-defensin	985:994	arg1	expression					959:968	expression	959:968	expression	959:968	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	2	4	theme	35-week-old	388:398	arg1	layers					414:419	288 35-week-old Hy-Line Brown layers	384:419	288 35-week-old Hy-Line Brown layers	384:419	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	8	5	from	enhancer	1524:1531	arg1	hens					1543:1546	laying hens	1536:1546	laying hens	1536:1546	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	6	6	theme	serum	945:949	arg1	IgM					951:953	serum IgM	945:953	serum IgM	945:953	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	7	theme	serum	1043:1047	arg1	IL-6					1049:1052	serum IL-6	1043:1052	serum IL-6	1043:1052	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	1	8	theme	yeast	184:188	arg1	YCWP					217:220	YCWP	217:220	YCWP	217:220	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	8	theme	yeast	184:188	arg1	polysaccharides					200:214	yeast cell-wall polysaccharides	184:214	yeast cell-wall polysaccharides (YCWP)	184:221	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	9	theme	immunomodulatory	279:294	arg1	Effects					146:152	Effects	146:152	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance	146:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	9	theme	immunomodulatory	279:294	arg1	effects					318:324	immunomodulatory and anti-inflammatory effects	279:324	immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens	279:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	6	10	theme	IL-6	1124:1127	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	10	theme	IL-6	1124:1127	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	3	11	theme	12-week	526:532	arg1	period					542:547	a 12-week feeding period	524:547	a 12-week feeding period	524:547	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	5	12	theme	egg	828:830	arg1	production					832:841	egg production	828:841	egg production	828:841	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	7	13	theme	Candidatus_Arthromitus	1342:1363	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	13	theme	Candidatus_Arthromitus	1342:1363	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	13	theme	Candidatus_Arthromitus	1342:1363	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	6	14	theme	IL-1β	1099:1103	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	14	theme	IL-1β	1099:1103	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	15	theme	Dietary	923:929	arg1	YCWP					931:934	Dietary YCWP	923:934	Dietary YCWP	923:934	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	5	16	theme	YCWP	911:914	arg1	group					916:920	the 1000 mg/kg YCWP group	896:920	the 1000 mg/kg YCWP group	896:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	1	17	theme	anti-inflammatory	300:316	arg1	Effects					146:152	Effects	146:152	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance	146:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	17	theme	anti-inflammatory	300:316	arg1	effects					318:324	immunomodulatory and anti-inflammatory effects	279:324	immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens	279:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	0	18	theme	laying	133:138	arg1	hens					140:143	LPS-challenged laying hens	118:143	LPS-challenged laying hens	118:143	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	7	19	theme	reduced	1416:1422	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	2	20	theme	dietary	451:457	arg1	treatments					459:468	4 dietary treatments	449:468	4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP	449:501	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	6	21	theme	TNF-α	1106:1110	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	21	theme	TNF-α	1106:1110	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	7	22	theme	microbial	1271:1279	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	1	23	theme	cell-wall	190:198	arg1	YCWP					217:220	YCWP	217:220	YCWP	217:220	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	23	theme	cell-wall	190:198	arg1	polysaccharides					200:214	yeast cell-wall polysaccharides	184:214	yeast cell-wall polysaccharides (YCWP)	184:221	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	0	24	theme	LPS-challenged	118:131	arg1	hens					140:143	LPS-challenged laying hens	118:143	LPS-challenged laying hens	118:143	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	7	25	theme	Desulfovibrio	1397:1409	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	25	theme	Desulfovibrio	1397:1409	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	25	theme	Desulfovibrio	1397:1409	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	6	26	theme	IL-1β	1058:1062	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	26	theme	IL-1β	1058:1062	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	1	27	from	Effects	146:152	arg1	performance					237:247	production performance	226:247	production performance	226:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	7	28	theme	Bacillaceae	1380:1390	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	28	theme	Bacillaceae	1380:1390	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	28	theme	Bacillaceae	1380:1390	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	1	29	theme	polysaccharides	200:214	arg1	supplementation					165:179	dietary supplementation	157:179	dietary supplementation of yeast cell-wall polysaccharides (YCWP)	157:221	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	0	30	theme	cell-wall	6:14	arg1	polysaccharides					16:30	Yeast cell-wall polysaccharides	0:30	Yeast cell-wall polysaccharides	0:30	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	3	31	theme	feeding	534:540	arg1	period					542:547	a 12-week feeding period	524:547	a 12-week feeding period	524:547	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	1	32	from	effects	318:324	arg1	hens					351:354	LPS-challenged laying hens	329:354	LPS-challenged laying hens	329:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	3	33	theme	birds	564:568	arg1	total					552:556	a total	550:556	a total of 32 birds	550:568	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	7	34	theme	immunomodulatory	1195:1210	arg1	effects					1212:1218	anti-inflammatory and immunomodulatory effects	1173:1218	anti-inflammatory and immunomodulatory effects of YCWP	1173:1226	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	5	35	theme	feed	808:811	arg1	efficiency					813:822	feed efficiency	808:822	feed efficiency	808:822	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	0	36	theme	Yeast	0:4	arg1	polysaccharides					16:30	Yeast cell-wall polysaccharides	0:30	Yeast cell-wall polysaccharides	0:30	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	4	37	theme	Escherichia	684:694	arg1	LPS					701:703	Escherichia coli LPS	684:703	Escherichia coli LPS	684:703	For each group, half (n = 8) received Escherichia coli LPS and half (n = 8) received PBS at 1 mg/kg body weight, intravenously.					
36270403	7	38	theme	YCWP	1223:1226	arg1	effects					1212:1218	anti-inflammatory and immunomodulatory effects	1173:1218	anti-inflammatory and immunomodulatory effects of YCWP	1173:1226	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	2	39	theme	layers	414:419	arg1	total					375:379	A total	373:379	A total of 288 35-week-old Hy-Line Brown layers	373:419	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	6	40	theme	LPS-induced	1012:1022	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	5	41	theme	laying	866:871	arg1	performance					873:883	optimal laying performance	858:883	optimal laying performance notable in the 1000 mg/kg YCWP group	858:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	8	42	contain	has	1463:1465	arg1	YCWP					1458:1461	YCWP	1458:1461	YCWP	1458:1461	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	8	42	contain	has	1463:1465	arg2	potentials					1471:1480	the potentials	1467:1480	the potentials	1467:1480	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	5	43	theme	notable	885:891	arg1	performance					873:883	optimal laying performance	858:883	optimal laying performance notable in the 1000 mg/kg YCWP group	858:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	1	44	theme	LPS-challenged	329:342	arg1	hens					351:354	LPS-challenged laying hens	329:354	LPS-challenged laying hens	329:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	6	45	theme	IFN-γ	1113:1117	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	45	theme	IFN-γ	1113:1117	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	46	theme	up-regulated	1072:1083	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	2	47	theme	Brown	408:412	arg1	layers					414:419	288 35-week-old Hy-Line Brown layers	384:419	288 35-week-old Hy-Line Brown layers	384:419	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	1	48	theme	laying	344:349	arg1	hens					351:354	LPS-challenged laying hens	329:354	LPS-challenged laying hens	329:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	6	49	theme	avian	979:983	arg1	β-defensin					985:994	ileal avian β-defensin	973:994	ileal avian β-defensin	973:994	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	7	50	theme	enhancement	1249:1259	arg1	effect					1261:1266	its enhancement effect	1245:1266	its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella	1245:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	1	51	theme	production	226:235	arg1	performance					237:247	production performance	226:247	production performance	226:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	6	52	theme	elevated	1024:1031	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	8	53	theme	gut	1520:1522	arg1	enhancer					1524:1531	gut enhancer	1520:1531	gut enhancer in laying hens	1520:1546	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	3	54	theme	1000 mg/kg	614:623	arg1	group					630:634	the control (n = 16) and 1000 mg/kg YCWP group	589:634	group	630:634	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	3	55	theme	control	593:599	arg1	n = 16					602:607	the control (n = 16) and 1000 mg/kg YCWP group	589:634	n = 16	602:607	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	3	55	theme	control	593:599	arg1	n = 16					637:642	n = 16	637:642	n = 16	637:642	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	6	56	theme	ileal	973:977	arg1	β-defensin					985:994	ileal avian β-defensin	973:994	ileal avian β-defensin	973:994	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	0	57	theme	inflammatory	63:74	arg1	response					76:83	inflammatory response	63:83	inflammatory response	63:83	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	3	58	theme	YCWP	625:628	arg1	group					630:634	the control (n = 16) and 1000 mg/kg YCWP group	589:634	group	630:634	After a 12-week feeding period, a total of 32 birds were selected from the control (n = 16) and 1000 mg/kg YCWP group (n = 16).					
36270403	2	59	dep	treatments	459:468	arg1	YCWP					498:501	0, 250, 500 and 1000 mg/kg YCWP	471:501	4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP	449:501	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	6	60	theme	IL-6	1049:1052	arg1	levels					1033:1038	the LPS-induced elevated levels	1008:1038	the LPS-induced elevated levels of serum IL-6 and IL-1β	1008:1062	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	60	theme	IL-6	1049:1052	arg1	expression					1085:1094	the up-regulated expression	1068:1094	the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6	1068:1127	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	6	61	theme	ileal	1146:1150	arg1	mucosa					1152:1157	ileal mucosa	1146:1157	ileal mucosa	1146:1157	Dietary YCWP enhanced serum IgM and expression of ileal avian β-defensin, alleviated the LPS-induced elevated levels of serum IL-6 and IL-1β and the up-regulated expression of IL-1β, TNF-α, IFN-γ, and IL-6 in spleen and/or ileal mucosa.					
36270403	8	62	theme	safe	1500:1503	arg1	prebiotics					1505:1514	safe prebiotics	1500:1514	safe prebiotics	1500:1514	Therefore, YCWP has the potentials to be utilized as safe prebiotics and gut enhancer in laying hens.					
36270403	7	63	theme	Bifidobacteriaceae	1309:1326	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	63	theme	Bifidobacteriaceae	1309:1326	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	63	theme	Bifidobacteriaceae	1309:1326	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	64	theme	anti-inflammatory	1173:1189	arg1	effects					1212:1218	anti-inflammatory and immunomodulatory effects	1173:1218	anti-inflammatory and immunomodulatory effects of YCWP	1173:1226	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	4	65	theme	body	746:749	arg1	weight					751:756	1 mg/kg body weight	738:756	1 mg/kg body weight	738:756	For each group, half (n = 8) received Escherichia coli LPS and half (n = 8) received PBS at 1 mg/kg body weight, intravenously.					
36270403	5	66	theme	optimal	858:864	arg1	performance					873:883	optimal laying performance	858:883	optimal laying performance notable in the 1000 mg/kg YCWP group	858:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	5	67	theme	1000 mg/kg	900:909	arg1	group					916:920	the 1000 mg/kg YCWP group	896:920	the 1000 mg/kg YCWP group	896:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	1	68	theme	supplementation	165:179	arg1	Effects					146:152	Effects	146:152	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance	146:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	68	theme	supplementation	165:179	arg1	effects					318:324	immunomodulatory and anti-inflammatory effects	279:324	immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens	279:354	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	68	theme	supplementation	165:179	arg1	composition					266:276	ileal microbial composition	250:276	ileal microbial composition	250:276	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	69	theme	ileal	250:254	arg1	Effects					146:152	Effects	146:152	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance	146:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	69	theme	ileal	250:254	arg1	composition					266:276	ileal microbial composition	250:276	ileal microbial composition	250:276	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	0	70	from	microbiota	104:113	arg1	hens					140:143	LPS-challenged laying hens	118:143	LPS-challenged laying hens	118:143	Yeast cell-wall polysaccharides improve immunity and attenuate inflammatory response via modulating gut microbiota in LPS-challenged laying hens.					
36270403	4	71	theme	1 mg/kg	738:744	arg1	weight					751:756	1 mg/kg body weight	738:756	1 mg/kg body weight	738:756	For each group, half (n = 8) received Escherichia coli LPS and half (n = 8) received PBS at 1 mg/kg body weight, intravenously.					
36270403	1	72	theme	dietary	157:163	arg1	supplementation					165:179	dietary supplementation	157:179	dietary supplementation of yeast cell-wall polysaccharides (YCWP)	157:221	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	5	73	from	notable	885:891	arg1	group					916:920	the 1000 mg/kg YCWP group	896:920	the 1000 mg/kg YCWP group	896:920	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
36270403	1	74	theme	microbial	256:264	arg1	Effects					146:152	Effects	146:152	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance	146:247	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	1	74	theme	microbial	256:264	arg1	composition					266:276	ileal microbial composition	250:276	ileal microbial composition	250:276	Effects of dietary supplementation of yeast cell-wall polysaccharides (YCWP) on production performance, ileal microbial composition, immunomodulatory and anti-inflammatory effects in LPS-challenged laying hens, were evaluated.					
36270403	7	75	theme	Shigella	1437:1444	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	75	theme	Shigella	1437:1444	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	75	theme	Shigella	1437:1444	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	4	76	dep	Escherichia	684:694	arg1	coli					696:699	coli	696:699	coli	696:699	For each group, half (n = 8) received Escherichia coli LPS and half (n = 8) received PBS at 1 mg/kg body weight, intravenously.					
36270403	7	77	from	effect	1261:1266	arg1	proliferation					1292:1304	proliferation	1292:1304	proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio	1292:1409	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	77	from	effect	1261:1266	arg1	diversity					1281:1289	microbial diversity	1271:1289	microbial diversity	1271:1289	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	7	77	from	effect	1261:1266	arg1	abundance					1424:1432	reduced abundance	1416:1432	reduced abundance of Shigella	1416:1444	Furthermore, anti-inflammatory and immunomodulatory effects of YCWP were linked with its enhancement effect on microbial diversity, proliferation of Bifidobacteriaceae, Lactocillus, Candidatus_Arthromitus, Streptomyces, Bacillaceae, and Desulfovibrio, and reduced abundance of Shigella.					
36270403	2	78	theme	Hy-Line	400:406	arg1	layers					414:419	288 35-week-old Hy-Line Brown layers	384:419	288 35-week-old Hy-Line Brown layers	384:419	A total of 288 35-week-old Hy-Line Brown layers were randomly assigned into 4 dietary treatments: 0, 250, 500 and 1000 mg/kg YCWP, respectively.					
36270403	5	79	from	group	916:920	arg1	notable					885:891	notable	885:891	notable	885:891	Results showed that YCWP enhanced feed efficiency and egg production linearly, with optimal laying performance notable in the 1000 mg/kg YCWP group.					
35587251	0	0	theme	PVA-PPU	77:83	arg1	scaffold					85:92	PVA-PPU scaffold	77:92	PVA-PPU scaffold	77:92	Comparison of engineered cartilage based on BMSCs and chondrocytes seeded on PVA-PPU scaffold in a sheep model.					
35587251	1	1	theme	polyvinyl	127:135	arg1	chains					154:159	polyvinyl alcohol hydrogel chains	127:159	polyvinyl alcohol hydrogel chains	127:159	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35587251	3	2	theme	safranin	465:472	arg1	staining					476:483	the Alcian Blue and safranin O staining	445:483	staining	476:483	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	4	3	theme	collagen	678:685	arg1	type					687:690	collagen type II	678:693	collagen type II	678:693	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	1	4	theme	cartilage	242:250	arg1	lesions					252:258	cartilage lesions	242:258	cartilage lesions	242:258	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35587251	6	5	theme	original	1094:1101	arg1	composition					1103:1113	their original composition	1088:1113	their original composition	1088:1113	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	4	6	theme	collagen	661:668	arg1	type					670:673	collagen type I	661:675	collagen type I	661:675	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	0	7	theme	sheep	99:103	arg1	model					105:109	a sheep model	97:109	a sheep model	97:109	Comparison of engineered cartilage based on BMSCs and chondrocytes seeded on PVA-PPU scaffold in a sheep model.					
35587251	6	8	theme	tissue	981:986	arg1	engineering					988:998	cartilage tissue engineering	971:998	cartilage tissue engineering	971:998	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	1	9	theme	hydrogel	145:152	arg1	chains					154:159	polyvinyl alcohol hydrogel chains	127:159	polyvinyl alcohol hydrogel chains	127:159	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35587251	5	10	theme	H&amp	819:823	arg1	analysis					827:834	the H&amp;E analysis	815:834	the H&amp;E analysis	815:834	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	6	11	theme	isolated	1022:1029	arg1	cultures					1043:1050	the isolated chondrocyte cultures	1018:1050	the isolated chondrocyte cultures on the synthesized substrate	1018:1079	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	4	12	theme	aggrecan	696:703	arg1	expression					647:656	the expression	643:656	the expression of collagen type I, collagen type II, aggrecan, and Sox9	643:713	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	3	13	attach	presence	507:514	arg2	proteoglycan					519:530	proteoglycan	519:530	proteoglycan	519:530	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	3	13	attach	presence	507:514	arg1	surface					539:545	the surface	535:545	the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes	535:627	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	6	14	theme	cartilage	971:979	arg1	engineering					988:998	cartilage tissue engineering	971:998	cartilage tissue engineering	971:998	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	3	15	dep	In	379:380	arg1	vitro					382:386	vitro	382:386	vitro	382:386	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	5	16	theme	other	840:844	arg1	tests					854:858	other related tests	840:858	other related tests	840:858	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	4	17	theme	synthesized	764:774	arg1	substrate					776:784	the synthesized substrate	760:784	the synthesized substrate	760:784	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	2	18	dep	in	304:305	arg1	vitro					307:311	vitro	307:311	vitro	307:311	The substrate was fully characterized, and in vitro and in vivo investigations were conducted based on a sheep model.					
35587251	0	19	theme	cartilage	25:33	arg1	Comparison					0:9	Comparison	0:9	Comparison of engineered cartilage	0:33	Comparison of engineered cartilage based on BMSCs and chondrocytes seeded on PVA-PPU scaffold in a sheep model.					
35587251	2	20	dep	in	317:318	arg1	vivo					320:323	vivo	320:323	vivo	320:323	The substrate was fully characterized, and in vitro and in vivo investigations were conducted based on a sheep model.					
35587251	3	21	theme	chondrocyte	422:432	arg1	cells					434:438	the chondrocyte cells	418:438	the chondrocyte cells	418:438	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	3	22	theme	proteoglycan	519:530	arg1	presence					507:514	the presence	503:514	the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes	503:627	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	5	23	theme	related	846:852	arg1	tests					854:858	other related tests	840:858	other related tests	840:858	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	1	24	theme	alcohol	137:143	arg1	chains					154:159	polyvinyl alcohol hydrogel chains	127:159	polyvinyl alcohol hydrogel chains	127:159	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35587251	6	25	theme	synthesized	1059:1069	arg1	substrate					1071:1079	the synthesized substrate	1055:1079	the synthesized substrate	1055:1079	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	3	26	theme	In	379:380	arg1	tests					388:392	In vitro tests	379:392	In vitro tests	379:392	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	5	27	theme	sheep	915:919	arg1	model					921:925	a sheep model	913:925	a sheep model	913:925	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	6	28	theme	chondrocyte	1031:1041	arg1	cultures					1043:1050	the isolated chondrocyte cultures	1018:1050	the isolated chondrocyte cultures on the synthesized substrate	1018:1079	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	2	29	theme	sheep	366:370	arg1	model					372:376	a sheep model	364:376	a sheep model	364:376	The substrate was fully characterized, and in vitro and in vivo investigations were conducted based on a sheep model.					
35587251	1	30	attach	crosslinked	166:176	arg3	study					120:124	this study	115:124	this study	115:124	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35587251	4	31	theme	type	687:690	arg1	expression					647:656	the expression	643:656	the expression of collagen type I, collagen type II, aggrecan, and Sox9	643:713	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	2	32	theme	in	317:318	arg1	investigations					325:338	in vitro and in vivo investigations	304:338	in vitro and in vivo investigations	304:338	The substrate was fully characterized, and in vitro and in vivo investigations were conducted based on a sheep model.					
35587251	4	33	theme	chondrocyte	736:746	arg1	cultures					748:755	the chondrocyte cultures	732:755	the chondrocyte cultures	732:755	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	6	34	from	cultures	1043:1050	arg1	substrate					1071:1079	the synthesized substrate	1055:1079	the synthesized substrate	1055:1079	The results were found to be promising for cartilage tissue engineering and verified that the isolated chondrocyte cultures on the synthesized substrate retain their original composition.					
35587251	5	35	theme	E	825:825	arg1	analysis					827:834	the H&amp;E analysis	815:834	the H&amp;E analysis	815:834	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	3	36	theme	synthesized	554:564	arg1	substrate					566:574	the synthesized substrate	550:574	the synthesized substrate	550:574	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	3	37	theme	chondrocytes	616:627	arg1	cultures					604:611	cultures	604:611	cultures of chondrocytes	604:627	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	3	38	theme	substrate	566:574	arg1	surface					539:545	the surface	535:545	the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes	535:627	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	4	39	theme	type	670:673	arg1	expression					647:656	the expression	643:656	the expression of collagen type I, collagen type II, aggrecan, and Sox9	643:713	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	3	40	from	presence	507:514	arg1	surface					539:545	the surface	535:545	the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes	535:627	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	5	41	theme	neocartilage	890:901	arg1	tissue					903:908	neocartilage tissue	890:908	neocartilage tissue	890:908	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	2	42	theme	in	304:305	arg1	investigations					325:338	in vitro and in vivo investigations	304:338	in vitro and in vivo investigations	304:338	The substrate was fully characterized, and in vitro and in vivo investigations were conducted based on a sheep model.					
35587251	4	43	theme	Sox9	710:713	arg1	expression					647:656	the expression	643:656	the expression of collagen type I, collagen type II, aggrecan, and Sox9	643:713	Furthermore, the expression of collagen type I, collagen type II, aggrecan, and Sox9 was presented in the chondrocyte cultures on the synthesized substrate through RT-PCR.					
35587251	3	44	theme	O	474:474	arg1	staining					476:483	the Alcian Blue and safranin O staining	445:483	staining	476:483	In vitro tests were performed based on the chondrocyte cells with the Alcian Blue and safranin O staining in order to prove the presence of proteoglycan on the surface of the synthesized substrate, which has been secreted by cultures of chondrocytes.					
35587251	5	45	theme	tissue	903:908	arg1	formation					877:885	the formation	873:885	the formation of neocartilage tissue	873:908	In addition, the H&amp;E analysis and other related tests demonstrated the formation of neocartilage tissue in a sheep model.					
35587251	0	46	theme	engineered	14:23	arg1	cartilage					25:33	engineered cartilage	14:33	engineered cartilage	14:33	Comparison of engineered cartilage based on BMSCs and chondrocytes seeded on PVA-PPU scaffold in a sheep model.					
35587251	1	47	theme	suitable	219:226	arg1	substrate					228:236	a suitable substrate	217:236	a suitable substrate for cartilage lesions	217:258	In this study, polyvinyl alcohol hydrogel chains were crosslinked by polyurethane in order to synthesize a suitable substrate for cartilage lesions.					
35797513	7	0	theme	alginate/GelMA	1263:1276	arg1	bioink					1293:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	8	1	theme	functional	1599:1608	arg1	regeneration					1617:1628	functional tissue regeneration	1599:1628	functional tissue regeneration	1599:1628	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	3	2	theme	Poly	561:564	arg1	fibers					592:597	Poly(lactic acid) (PLLA) short fibers	561:597	Poly(lactic acid) (PLLA) short fibers	561:597	Poly(lactic acid) (PLLA) short fibers are first prepared by electrospinning and then fragmented through aminolysis reaction.					
35797513	0	3	theme	Double-Network	88:101	arg1	Bioink					103:108	Microfiber-Reinforced Double-Network Bioink	66:108	Microfiber-Reinforced Double-Network Bioink	66:108	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	1	4	theme	big	374:376	arg1	challenge					378:386	a big challenge	372:386	a big challenge	372:386	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	1	4	theme	big	374:376	arg1	construction					271:282	construction	271:282	construction of mechanically competent tissue grafts which mimic irregular cartilage defect	271:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	5	5	theme	mechanically	960:971	arg1	constructs					980:989	mechanically strong constructs	960:989	mechanically strong constructs	960:989	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	1	6	theme	custom	191:196	arg1	shapes					198:203	custom shapes	191:203	custom shapes that resemble the complex architecture of human tissues	191:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	6	7	theme	bioink	1057:1062	arg1	composition					1064:1074	the bioink composition	1053:1074	the bioink composition	1053:1074	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	6	8	theme	compression	1165:1175	arg1	loading					1177:1183	100 cyclical compression loading	1152:1183	100 cyclical compression loading (up to 40% of strain)	1152:1205	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	8	9	theme	irregular	1517:1525	arg1	size					1527:1530	the irregular size	1513:1530	the irregular size	1513:1530	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	3	10	theme	lactic	566:571	arg1	Poly					561:564	Poly	561:564	Poly(lactic acid) (PLLA) short fibers	561:597	Poly(lactic acid) (PLLA) short fibers are first prepared by electrospinning and then fragmented through aminolysis reaction.					
35797513	3	10	theme	lactic	566:571	arg1	acid					573:576	lactic acid	566:576	lactic acid	566:576	Poly(lactic acid) (PLLA) short fibers are first prepared by electrospinning and then fragmented through aminolysis reaction.					
35797513	4	11	theme	oxidized	802:809	arg1	bioink					820:825	oxidized alginate bioink	802:825	oxidized alginate bioink	802:825	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	7	12	theme	reinforced	1252:1261	arg1	bioink					1293:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	4	13	with	microfibers	753:763	arg1	lengths					789:795	lengths	789:795	lengths	789:795	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	4	13	with	microfibers	753:763	arg1	amounts					777:783	varied amounts	770:783	varied amounts	770:783	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	1	14	with	scaffolds	176:184	arg1	shapes					198:203	custom shapes	191:203	custom shapes that resemble the complex architecture of human tissues	191:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	4	15	theme	microfibers	753:763	arg1	incorporation					725:737	an incorporation	722:737	an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink	722:825	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	1	16	theme	competent	300:308	arg1	grafts					317:322	mechanically competent tissue grafts	287:322	mechanically competent tissue grafts which mimic irregular cartilage defect	287:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	4	17	theme	varied	770:775	arg1	amounts					777:783	varied amounts	770:783	varied amounts	770:783	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	5	18	theme	PLLA	867:870	arg1	fibers					878:883	PLLA short fibers	867:883	PLLA short fibers	867:883	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	2	19	theme	fiber-reinforced	416:431	arg1	bioink					448:453	short fiber-reinforced double-network bioink	410:453	short fiber-reinforced double-network bioink	410:453	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	2	20	theme	tunable	504:510	arg1	scaffold					512:519	anatomically accurate and mechanical tunable scaffold	467:519	anatomically accurate and mechanical tunable scaffold for cartilage regeneration	467:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	5	21	theme	strong	973:978	arg1	constructs					980:989	mechanically strong constructs	960:989	mechanically strong constructs	960:989	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	2	22	theme	cartilage	525:533	arg1	regeneration					535:546	cartilage regeneration	525:546	cartilage regeneration	525:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	5	23	theme	short	872:876	arg1	fibers					878:883	PLLA short fibers	867:883	PLLA short fibers	867:883	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	6	24	theme	cyclical	1156:1163	arg1	loading					1177:1183	100 cyclical compression loading	1152:1183	100 cyclical compression loading (up to 40% of strain)	1152:1205	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	2	25	theme	short	410:414	arg1	bioink					448:453	short fiber-reinforced double-network bioink	410:453	short fiber-reinforced double-network bioink	410:453	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	0	26	theme	Contour	3:9	arg1	Printing					11:18	3D Contour Printing	0:18	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.	0:109	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	7	27	theme	double-network	1278:1291	arg1	bioink					1293:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	this mechanically reinforced alginate/GelMA double-network bioink	1234:1298	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	7	28	theme	marrow-derived	1349:1362	arg1	chondrogenesis					1377:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	0	29	theme	3D	0:1	arg1	Printing					11:18	3D Contour Printing	0:18	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.	0:109	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	1	30	theme	tissue	310:315	arg1	grafts					317:322	mechanically competent tissue grafts	287:322	mechanically competent tissue grafts which mimic irregular cartilage defect	287:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	6	31	theme	kPa	1137:1139	arg1	stress					1122:1127	a compressive stress	1108:1127	a compressive stress of ≈150 kPa	1108:1139	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	2	32	theme	accurate	480:487	arg1	scaffold					512:519	anatomically accurate and mechanical tunable scaffold	467:519	anatomically accurate and mechanical tunable scaffold for cartilage regeneration	467:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	1	33	theme	grafts	317:322	arg1	challenge					378:386	a big challenge	372:386	a big challenge	372:386	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	1	33	theme	grafts	317:322	arg1	construction					271:282	construction	271:282	construction of mechanically competent tissue grafts which mimic irregular cartilage defect	271:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	6	34	dep	loading	1177:1183	arg1	strain					1199:1204	strain	1199:1204	strain	1199:1204	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	6	34	dep	loading	1177:1183	arg1	%					1194:1194	up to 40%	1186:1194	up to 40% of strain	1186:1204	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	3	35	theme	short	586:590	arg1	fibers					592:597	Poly(lactic acid) (PLLA) short fibers	561:597	Poly(lactic acid) (PLLA) short fibers	561:597	Poly(lactic acid) (PLLA) short fibers are first prepared by electrospinning and then fragmented through aminolysis reaction.					
35797513	6	36	with	constructs	1092:1101	arg1	stress					1122:1127	a compressive stress	1108:1127	a compressive stress of ≈150 kPa	1108:1139	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	1	37	theme	complex	223:229	arg1	architecture					231:242	the complex architecture	219:242	the complex architecture of human tissues	219:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	4	38	theme	fragmented	742:751	arg1	microfibers					753:763	fragmented microfibers	742:763	fragmented microfibers with varied amounts and lengths	742:795	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	2	39	theme	3D	395:396	arg1	printing					398:405	3D printing	395:405	3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration	395:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	0	40	theme	Mimetic	36:42	arg1	Grafts					54:59	Anatomically Mimetic Cartilage Grafts	23:59	Anatomically Mimetic Cartilage Grafts	23:59	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	4	41	theme	Composite	686:694	arg1	inks					696:699	Composite inks	686:699	Composite inks	686:699	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	8	42	dep	engineered	1480:1489	arg1	printing					1471:1478	printing	1471:1478	printing	1471:1478	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	2	43	theme	bioink	448:453	arg1	printing					398:405	3D printing	395:405	3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration	395:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	0	44	theme	Anatomically	23:34	arg1	Grafts					54:59	Anatomically Mimetic Cartilage Grafts	23:59	Anatomically Mimetic Cartilage Grafts	23:59	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	1	45	theme	irregular	336:344	arg1	defect					356:361	irregular cartilage defect	336:361	irregular cartilage defect	336:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	5	46	theme	fibers	878:883	arg1	incorporation					850:862	incorporation	850:862	incorporation of PLLA short fibers	850:883	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	5	47	theme	printing	907:914	arg1	fidelity					916:923	the printing fidelity	903:923	the printing fidelity	903:923	The results show that incorporation of PLLA short fibers not only improves the printing fidelity but also facilitates in generating mechanically strong constructs.					
35797513	1	48	theme	human	247:251	arg1	tissues					253:259	human tissues	247:259	human tissues	247:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	0	49	theme	Grafts	54:59	arg1	Printing					11:18	3D Contour Printing	0:18	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.	0:109	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	1	50	theme	cartilage	346:354	arg1	defect					356:361	irregular cartilage defect	336:361	irregular cartilage defect	336:361	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	6	51	theme	compressive	1110:1120	arg1	stress					1122:1127	a compressive stress	1108:1127	a compressive stress of ≈150 kPa	1108:1139	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	8	52	theme	cartilage	1561:1569	arg1	size					1527:1530	the irregular size	1513:1530	the irregular size	1513:1530	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	8	52	theme	cartilage	1561:1569	arg1	properties					1547:1556	mechanical properties	1536:1556	mechanical properties	1536:1556	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	0	53	with	Printing	11:18	arg1	Bioink					103:108	Microfiber-Reinforced Double-Network Bioink	66:108	Microfiber-Reinforced Double-Network Bioink	66:108	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	1	54	theme	emerging	129:136	arg1	Bioprinting					111:121	Bioprinting	111:121	Bioprinting	111:121	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	1	54	theme	emerging	129:136	arg1	technology					138:147	an emerging technology	126:147	an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues	126:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	0	55	theme	Cartilage	44:52	arg1	Grafts					54:59	Anatomically Mimetic Cartilage Grafts	23:59	Anatomically Mimetic Cartilage Grafts	23:59	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	7	56	link	marrow-derived	1349:1362	arg1	chondrogenesis					1377:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	6	57	theme	strain	1199:1204	arg1	strain					1199:1204	strain	1199:1204	strain	1199:1204	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	6	57	theme	strain	1199:1204	arg1	%					1194:1194	up to 40%	1186:1194	up to 40% of strain	1186:1204	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	7	58	theme	stromal	1364:1370	arg1	chondrogenesis					1377:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	7	59	theme	cell	1372:1375	arg1	chondrogenesis					1377:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	bone marrow-derived stromal cell chondrogenesis	1344:1390	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	6	60	theme	gelatin	1009:1015	arg1	GelMA					1031:1035	GelMA	1031:1035	GelMA	1031:1035	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	6	60	theme	gelatin	1009:1015	arg1	methacryloyl					1017:1028	gelatin methacryloyl	1009:1028	gelatin methacryloyl (GelMA)	1009:1036	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	8	61	theme	grafts	1491:1496	arg1	capable					1460:1466	capable	1460:1466	capable	1460:1466	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	4	62	theme	alginate	811:818	arg1	bioink					820:825	oxidized alginate bioink	802:825	oxidized alginate bioink	802:825	Composite inks are constructed with an incorporation of fragmented microfibers with varied amounts and lengths into oxidized alginate bioink.					
35797513	1	63	theme	tissues	253:259	arg1	architecture					231:242	the complex architecture	219:242	the complex architecture of human tissues	219:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	3	64	theme	aminolysis	665:674	arg1	reaction					676:683	aminolysis reaction	665:683	aminolysis reaction	665:683	Poly(lactic acid) (PLLA) short fibers are first prepared by electrospinning and then fragmented through aminolysis reaction.					
35797513	1	65	theme	fabricating	153:163	arg1	scaffolds					176:184	fabricating cell-laden scaffolds	153:184	fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues	153:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	0	66	theme	Microfiber-Reinforced	66:86	arg1	Bioink					103:108	Microfiber-Reinforced Double-Network Bioink	66:108	Microfiber-Reinforced Double-Network Bioink	66:108	3D Contour Printing of Anatomically Mimetic Cartilage Grafts with Microfiber-Reinforced Double-Network Bioink.					
35797513	2	67	theme	double-network	433:446	arg1	bioink					448:453	short fiber-reinforced double-network bioink	410:453	short fiber-reinforced double-network bioink	410:453	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	8	68	theme	mechanical	1536:1545	arg1	properties					1547:1556	mechanical properties	1536:1556	mechanical properties	1536:1556	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	1	69	theme	cell-laden	165:174	arg1	scaffolds					176:184	fabricating cell-laden scaffolds	153:184	fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues	153:259	Bioprinting is an emerging technology for fabricating cell-laden scaffolds with custom shapes that resemble the complex architecture of human tissues, however, construction of mechanically competent tissue grafts which mimic irregular cartilage defect is still a big challenge.					
35797513	8	70	theme	engineered	1480:1489	arg1	grafts					1491:1496	printing engineered grafts	1471:1496	printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration	1471:1628	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	8	71	theme	tissue	1610:1615	arg1	regeneration					1617:1628	functional tissue regeneration	1599:1628	functional tissue regeneration	1599:1628	Collectively, these findings demonstrate this approach is capable of printing engineered grafts which resemble the irregular size and mechanical properties of cartilage and thus hold potential for functional tissue regeneration.					
35797513	6	72	dep	40	1192:1193	arg1	to					1189:1190	to	1189:1190	to	1189:1190	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35797513	2	73	theme	mechanical	493:502	arg1	scaffold					512:519	anatomically accurate and mechanical tunable scaffold	467:519	anatomically accurate and mechanical tunable scaffold for cartilage regeneration	467:546	Here, 3D printing of short fiber-reinforced double-network bioink to generate anatomically accurate and mechanical tunable scaffold for cartilage regeneration is reported.					
35797513	7	74	theme	good	1309:1312	arg1	biocompatibility					1314:1329	good biocompatibility	1309:1329	good biocompatibility	1309:1329	In addition, this mechanically reinforced alginate/GelMA double-network bioink displays good biocompatibility and supports bone marrow-derived stromal cell chondrogenesis in vitro.					
35797513	6	75	theme	fabricated	1081:1090	arg1	constructs					1092:1101	the fabricated constructs	1077:1101	the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain)	1077:1205	By incorporating gelatin methacryloyl (GelMA) and optimizing the bioink composition, the fabricated constructs with a compressive stress of ≈150 kPa even after 100 cyclical compression loading (up to 40% of strain) are achieved.					
35041790	0	0	theme	High	83:86	arg1	Production					107:116	High Yield Carbon Fiber Production	83:116	High Yield Carbon Fiber Production	83:116	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	6	1	theme	catalysts	1214:1222	arg1	H3PO4					1323:1327	H3PO4	1323:1327	H3PO4	1323:1327	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	1	theme	catalysts	1214:1222	arg1	range					1195:1199	A range	1193:1199	A range of different catalysts are evaluated for their ability to enhance the char yield	1193:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	1	theme	catalysts	1214:1222	arg1	retardant					1312:1320	a phosphorus-based flame retardant	1287:1320	a phosphorus-based flame retardant (H3PO4)	1287:1328	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	1	theme	catalysts	1214:1222	arg1	effective					1352:1360	effective	1352:1360	effective	1352:1360	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	4	2	theme	carbon	847:852	arg1	yield					854:858	the carbon yield	843:858	the carbon yield	843:858	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	1	3	with	years	232:236	arg1	much					243:246	much	243:246	much	243:246	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	6	4	theme	char	1390:1393	arg1	yield					1395:1399	the char yield	1386:1399	the char yield	1386:1399	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	5	5	theme	oxygen	1120:1125	arg1	mechanism					1079:1087	the stabilization mechanism	1061:1087	the stabilization mechanism	1061:1087	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	5	theme	oxygen	1120:1125	arg1	effect					1110:1115	the accelerating effect	1093:1115	the accelerating effect of oxygen and increased char yield (carbon content)	1093:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	1	6	theme	bio-based	155:163	arg1	resources					178:186	bio-based or renewable resources	155:186	bio-based or renewable resources	155:186	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	6	7	dep	catalysts	1214:1222	arg1	evaluated					1228:1236	evaluated	1228:1236	are evaluated for their ability to enhance the char yield	1224:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	0	8	theme	Carbon	94:99	arg1	Production					107:116	High Yield Carbon Fiber Production	83:116	High Yield Carbon Fiber Production	83:116	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	3	9	theme	different	671:679	arg1	profiles					695:702	different stabilization profiles	671:702	different stabilization profiles	671:702	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	5	10	theme	yield	1146:1150	arg1	mechanism					1079:1087	the stabilization mechanism	1061:1087	the stabilization mechanism	1061:1087	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	10	theme	yield	1146:1150	arg1	effect					1110:1115	the accelerating effect	1093:1115	the accelerating effect of oxygen and increased char yield (carbon content)	1093:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	0	11	theme	Yield	88:92	arg1	Production					107:116	High Yield Carbon Fiber Production	83:116	High Yield Carbon Fiber Production	83:116	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	5	12	theme	Carbon	900:905	arg1	dioxide					907:913	Carbon dioxide	900:913	Carbon dioxide	900:913	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	4	13	theme	alternative	818:828	arg1	catalysts					830:838	alternative catalysts	818:838	alternative catalysts	818:838	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	2	14	theme	stabilization	403:415	arg1	step					345:348	A critical step	334:348	A critical step in optimizing the manufacture of carbon fiber	334:394	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	14	theme	stabilization	403:415	arg1	process					417:423	the stabilization process	399:423	the stabilization process	399:423	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	15	theme	fiber	390:394	arg1	manufacture					368:378	the manufacture	364:378	the manufacture of carbon fiber	364:394	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	0	16	theme	Fiber	101:105	arg1	Production					107:116	High Yield Carbon Fiber Production	83:116	High Yield Carbon Fiber Production	83:116	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	4	17	theme	atmosphere	754:763	arg1	influence					741:749	the influence	737:749	the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization	737:897	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	1	18	theme	renewable	168:176	arg1	resources					178:186	bio-based or renewable resources	155:186	bio-based or renewable resources	155:186	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	5	19	theme	accelerating	1097:1108	arg1	effect					1110:1115	the accelerating effect	1093:1115	the accelerating effect of oxygen and increased char yield (carbon content)	1093:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	20	theme	carbon	1153:1158	arg1	yield					1146:1150	increased char yield	1131:1150	increased char yield (carbon content)	1131:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	20	theme	carbon	1153:1158	arg1	content					1160:1166	carbon content	1153:1166	carbon content	1153:1166	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	21	dep	infrared	995:1002	arg1	FTIR					1005:1008	FTIR	1005:1008	FTIR	1005:1008	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	3	22	used	used	614:617	arg2	TGA					606:608	TGA	606:608	TGA	606:608	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	3	22	used	used	614:617	arg2	analysis					596:603	thermogravimetric analysis	578:603	thermogravimetric analysis (TGA)	578:609	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	4	23	theme	catalysts	830:838	arg1	influence					741:749	the influence	737:749	the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization	737:897	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	6	24	located	observed	1405:1412	arg2	doubling					1374:1381	doubling	1374:1381	doubling	1374:1381	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	24	located	observed	1405:1412	arg1	fact					1366:1369	fact	1366:1369	fact	1366:1369	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	4	25	theme	stabilization	885:897	arg1	efficiency					861:870	efficiency	861:870	efficiency	861:870	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	25	theme	stabilization	885:897	arg1	rate					877:880	rate	877:880	rate	877:880	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	25	theme	stabilization	885:897	arg1	yield					854:858	the carbon yield	843:858	the carbon yield	843:858	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	26	from	influence	741:749	arg1	efficiency					861:870	efficiency	861:870	efficiency	861:870	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	26	from	influence	741:749	arg1	rate					877:880	rate	877:880	rate	877:880	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	26	from	influence	741:749	arg1	yield					854:858	the carbon yield	843:858	the carbon yield	843:858	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	5	27	theme	water	919:923	arg1	vapor					925:929	water vapor	919:929	water vapor released during stabilization	919:959	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	28	theme	infrared	995:1002	arg1	spectroscopy					1011:1022	infrared (FTIR) spectroscopy	995:1022	infrared (FTIR) spectroscopy	995:1022	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	29	dep	Fourier	977:983	arg1	transform					985:993	transform	985:993	transform infrared (FTIR) spectroscopy	985:1022	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	6	30	theme	phosphorus-based	1289:1304	arg1	H3PO4					1323:1327	H3PO4	1323:1327	H3PO4	1323:1327	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	30	theme	phosphorus-based	1289:1304	arg1	range					1195:1199	A range	1193:1199	A range of different catalysts are evaluated for their ability to enhance the char yield	1193:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	30	theme	phosphorus-based	1289:1304	arg1	retardant					1312:1320	a phosphorus-based flame retardant	1287:1320	a phosphorus-based flame retardant (H3PO4)	1287:1328	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	30	theme	phosphorus-based	1289:1304	arg1	effective					1352:1360	effective	1352:1360	effective	1352:1360	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	1	31	theme	considerable	199:210	arg1	attention					212:220	considerable attention	199:220	considerable attention	199:220	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	0	32	theme	Cellulose-Lignin	42:57	arg1	Precursor					59:67	a Cellulose-Lignin Precursor	40:67	a Cellulose-Lignin Precursor	40:67	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	4	33	theme	cellulose-lignin	784:799	arg1	composition					801:811	cellulose-lignin composition	784:811	cellulose-lignin composition	784:811	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	6	34	theme	different	1204:1212	arg1	catalysts					1214:1222	different catalysts	1204:1222	different catalysts are evaluated for their ability to enhance the char yield	1204:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	2	35	theme	physical	457:464	arg1	transformed					502:512	transformed	502:512	transformed	502:512	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	35	theme	physical	457:464	arg1	structure					466:474	the chemical and physical structure	440:474	the chemical and physical structure of the precursor fiber	440:497	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	5	36	theme	increased	1131:1139	arg1	yield					1146:1150	increased char yield	1131:1150	increased char yield (carbon content)	1131:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	36	theme	increased	1131:1139	arg1	content					1160:1166	carbon content	1153:1166	carbon content	1153:1166	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	3	37	theme	thermogravimetric	578:594	arg1	TGA					606:608	TGA	606:608	TGA	606:608	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	3	37	theme	thermogravimetric	578:594	arg1	analysis					596:603	thermogravimetric analysis	578:603	thermogravimetric analysis (TGA)	578:609	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	1	38	theme	cellulose-lignin	289:304	arg1	fibers					326:331	cellulose-lignin composite precursor fibers	289:331	cellulose-lignin composite precursor fibers	289:331	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	5	39	theme	stabilization	1065:1077	arg1	mechanism					1079:1087	the stabilization mechanism	1061:1087	the stabilization mechanism	1061:1087	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	2	40	theme	critical	336:343	arg1	step					345:348	A critical step	334:348	A critical step in optimizing the manufacture of carbon fiber	334:394	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	40	theme	critical	336:343	arg1	process					417:423	the stabilization process	399:423	the stabilization process	399:423	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	0	41	theme	Precursor	59:67	arg1	Stabilization					23:35	Stabilization	23:35	Stabilization of a Cellulose-Lignin Precursor	23:67	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	0	41	theme	Precursor	59:67	arg1	Route					74:78	a Route	72:78	a Route to High Yield Carbon Fiber Production	72:116	Chemically Accelerated Stabilization of a Cellulose-Lignin Precursor as a Route to High Yield Carbon Fiber Production.					
35041790	1	42	theme	composite	306:314	arg1	fibers					326:331	cellulose-lignin composite precursor fibers	289:331	cellulose-lignin composite precursor fibers	289:331	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	6	43	theme	flame	1306:1310	arg1	H3PO4					1323:1327	H3PO4	1323:1327	H3PO4	1323:1327	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	43	theme	flame	1306:1310	arg1	range					1195:1199	A range	1193:1199	A range of different catalysts are evaluated for their ability to enhance the char yield	1193:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	43	theme	flame	1306:1310	arg1	retardant					1312:1320	a phosphorus-based flame retardant	1287:1320	a phosphorus-based flame retardant (H3PO4)	1287:1328	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	6	43	theme	flame	1306:1310	arg1	effective					1352:1360	effective	1352:1360	effective	1352:1360	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	2	44	theme	chemical	444:451	arg1	transformed					502:512	transformed	502:512	transformed	502:512	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	44	theme	chemical	444:451	arg1	structure					466:474	the chemical and physical structure	440:474	the chemical and physical structure of the precursor fiber	440:497	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	4	45	theme	composition	801:811	arg1	influence					741:749	the influence	737:749	the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization	737:897	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	1	46	theme	precursor	316:324	arg1	fibers					326:331	cellulose-lignin composite precursor fibers	289:331	cellulose-lignin composite precursor fibers	289:331	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	6	47	theme	char	1271:1274	arg1	yield					1276:1280	the char yield	1267:1280	the char yield	1267:1280	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	1	48	theme	recent	225:230	arg1	years					232:236	recent years	225:236	recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers	225:331	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	2	49	theme	high	545:548	arg1	temperatures					550:561	very high temperatures	540:561	very high temperatures	540:561	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	1	50	from	resources	178:186	arg1	production					123:132	The production	119:132	The production of carbon fiber from bio-based or renewable resources	119:186	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	4	51	dep	atmosphere	754:763	arg1	air					778:780	air	778:780	air	778:780	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	4	51	dep	atmosphere	754:763	arg1	nitrogen					766:773	nitrogen	766:773	nitrogen	766:773	Using this approach, we explore the influence of atmosphere (nitrogen or air), cellulose-lignin composition, and alternative catalysts on the carbon yield, efficiency, and rate of stabilization.					
35041790	2	52	theme	fiber	493:497	arg1	transformed					502:512	transformed	502:512	transformed	502:512	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	52	theme	fiber	493:497	arg1	structure					466:474	the chemical and physical structure	440:474	the chemical and physical structure of the precursor fiber	440:497	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	5	53	theme	further	1035:1041	arg1	information					1043:1053	further information	1035:1053	further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content)	1035:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	1	54	theme	carbon	137:142	arg1	fiber					144:148	carbon fiber	137:148	carbon fiber	137:148	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	2	55	theme	carbon	383:388	arg1	fiber					390:394	carbon fiber	383:394	carbon fiber	383:394	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	2	56	theme	precursor	483:491	arg1	fiber					493:497	the precursor fiber	479:497	the precursor fiber	479:497	A critical step in optimizing the manufacture of carbon fiber is the stabilization process, through which the chemical and physical structure of the precursor fiber is transformed, allowing it to withstand very high temperatures.					
35041790	3	57	theme	stabilization	681:693	arg1	profiles					695:702	different stabilization profiles	671:702	different stabilization profiles	671:702	In this work, thermogravimetric analysis (TGA) is used to explore and optimize stabilization by simulating different stabilization profiles.					
35041790	1	58	theme	fiber	144:148	arg1	production					123:132	The production	119:132	The production of carbon fiber from bio-based or renewable resources	119:186	The production of carbon fiber from bio-based or renewable resources has gained considerable attention in recent years with much of the focus upon cellulose, lignin, and cellulose-lignin composite precursor fibers.					
35041790	6	59	theme	yield	1395:1399	arg1	doubling					1374:1381	doubling	1374:1381	doubling	1374:1381	A range of different catalysts are evaluated for their ability to enhance the char yield, and a phosphorus-based flame retardant (H3PO4) proved to be the most effective; in fact, a doubling of the char yield was observed.					
35041790	5	60	theme	char	1141:1144	arg1	yield					1146:1150	increased char yield	1131:1150	increased char yield (carbon content)	1131:1167	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
35041790	5	60	theme	char	1141:1144	arg1	content					1160:1166	carbon content	1153:1166	carbon content	1153:1166	Carbon dioxide and water vapor released during stabilization are analyzed by Fourier transform infrared (FTIR) spectroscopy, providing further information about the stabilization mechanism and the accelerating effect of oxygen and increased char yield (carbon content), especially for lignin.					
37188729	3	0	theme	cellulose	652:660	arg1	determination					635:647	the rapid determination	625:647	the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics	625:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	6	1	dep	RPD = 2.46	1261:1270	arg1	see					1283:1285	see	1283:1285	see text	1283:1290	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	2	2	dep	specie	418:423	arg1	avoid					429:433	avoid	429:433	to avoid illegal logging	426:449	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	5	3	theme	PLS	1132:1134	arg1	model					1136:1140	a three-species universal PLS model	1106:1140	a three-species universal PLS model to quantify the principal wood chemical components	1106:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	6	4	dep	Lignin	1194:1199	arg1	=					1234:1234	=	1234:1234	=	1234:1234	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	3	5	theme	rapid	629:633	arg1	determination					635:647	the rapid determination	625:647	the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics	625:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	6	6	dep	see	1379:1381	arg1	[Formula					1369:1376	[Formula	1369:1376	[Formula	1369:1376	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	0	7	dep	PLS-DA	121:126	arg1	PLS					129:131	PLS	129:131	PLS	129:131	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	4	8	theme	IR	1009:1010	arg1	peaks					1012:1016	IR peaks	1009:1016	IR peaks related to cellulose, lignin, and hemicellulose	1009:1064	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	0	9	theme	multivariate	98:109	arg1	PLS-DA					121:126	PLS-DA	121:126	PLS-DA	121:126	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	0	9	theme	multivariate	98:109	arg1	analysis					111:118	multivariate analysis	98:118	multivariate analysis (PLS-DA, PLS)	98:132	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	7	10	theme	wood	1554:1557	arg1	composition					1568:1578	the wood chemical composition	1550:1578	the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina	1550:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	2	11	theme	tree	488:491	arg1	programs					502:509	tree breeding programs	488:509	tree breeding programs	488:509	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	2	11	theme	tree	488:491	arg1	composition					475:485	chemical composition	466:485	chemical composition (tree breeding programs)	466:510	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	7	12	theme	Capirona	1610:1617	arg1	trees					1592:1596	juvenile trees	1583:1596	juvenile trees of Pashaco, Capirona, and Bolaina	1583:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	1	13	from	importance	289:298	arg1	Forest					314:319	Forest	314:319	Forest	314:319	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	7	14	dep	together	1455:1462	arg1	with					1464:1467	with	1464:1467	with	1464:1467	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	6	15	dep	see	1283:1285	arg1	[Formula					1273:1280	[Formula	1273:1280	[Formula	1273:1280	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	6	16	theme	cellulose	1340:1348	arg1	model					1350:1354	cellulose model	1340:1354	cellulose model (RPD = 3.43, [Formula: see text] = 0.91)	1340:1395	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	4	17	theme	full	943:946	arg1	spectra					948:954	the full spectra	939:954	the full spectra	939:954	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	5	18	theme	three-species	1108:1120	arg1	model					1136:1140	a three-species universal PLS model	1106:1140	a three-species universal PLS model to quantify the principal wood chemical components	1106:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	6	19	dep	see	1224:1226	arg1	[Formula					1214:1221	[Formula	1214:1221	[Formula	1214:1221	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	4	20	dep	species	809:815	arg1	sensibility					884:894	sensibility	884:894	sensibility	884:894	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	20	dep	species	809:815	arg1	species					809:815	wood species	804:815	wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%)	804:917	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	20	dep	species	809:815	arg1	accuracy					857:864	accuracy	857:864	accuracy	857:864	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	20	dep	species	809:815	arg1	specificity					867:877	specificity	867:877	specificity	867:877	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	20	dep	species	809:815	arg1	0.84 ≤ R2 ≤ 0.91					818:833	0.84 ≤ R2 ≤ 0.91	818:833	0.84 ≤ R2 ≤ 0.91	818:833	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	20	dep	species	809:815	arg1	0.12 ≤ RMSEP ≤ 0.20					836:854	0.12 ≤ RMSEP ≤ 0.20	836:854	0.12 ≤ RMSEP ≤ 0.20	836:854	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	3	21	theme	hemicellulose	663:675	arg1	determination					635:647	the rapid determination	625:647	the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics	625:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	4	22	theme	species	809:815	arg1	classification					786:799	the classification	782:799	the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%)	782:917	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	3	23	theme	FTIR	695:698	arg1	spectroscopy					700:711	FTIR spectroscopy	695:711	FTIR spectroscopy coupled with chemometrics	695:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	6	24	theme	good	1317:1320	arg1	prediction					1322:1331	a good prediction	1315:1331	a good prediction	1315:1331	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	1	25	theme	ecological	255:264	arg1	features					266:273	their ecological features	249:273	their ecological features	249:273	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	1	26	from	features	266:273	arg1	Forest					314:319	Forest	314:319	Forest	314:319	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	7	27	theme	Pashaco	1601:1607	arg1	trees					1592:1596	juvenile trees	1583:1596	juvenile trees of Pashaco, Capirona, and Bolaina	1583:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	0	28	theme	fast-growing	28:39	arg1	species					46:52	Amazonian fast-growing tree species	18:52	Amazonian fast-growing tree species	18:52	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	7	29	theme	reliable	1488:1495	arg1	method					1497:1502	a reliable method	1486:1502	a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina	1486:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	7	29	theme	reliable	1488:1495	arg1	chemometrics					1469:1480	chemometrics	1469:1480	chemometrics	1469:1480	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	7	29	theme	reliable	1488:1495	arg1	FTIR-ATR					1445:1452	FTIR-ATR	1445:1452	FTIR-ATR	1445:1452	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	6	30	theme	hemicellulose	1246:1258	arg1	models					1301:1306	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models	1194:1306	models	1301:1306	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	7	31	theme	Bolaina	1624:1630	arg1	trees					1592:1596	juvenile trees	1583:1596	juvenile trees of Pashaco, Capirona, and Bolaina	1583:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	7	32	theme	wood	1520:1523	arg1	species					1525:1531	wood species	1520:1531	wood species	1520:1531	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	1	33	from	industry	329:336	arg1	Forest					314:319	Forest	314:319	Forest	314:319	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	3	34	theme	lignin	682:687	arg1	determination					635:647	the rapid determination	625:647	the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics	625:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	6	35	dep	=	1293:1293	arg1	0.83					1295:1298	0.83	1295:1298	0.83	1295:1298	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	1	36	theme	wood-polymer	347:358	arg1	composites					360:369	wood-polymer composites	347:369	wood-polymer composites	347:369	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	6	37	dep	RPD = 2.27	1202:1211	arg1	see					1224:1226	see	1224:1226	see text	1224:1231	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	2	38	theme	practical	385:393	arg1	method					395:400	a practical method	383:400	a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs)	383:510	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	0	39	theme	species	46:52	arg1	Classification					0:13	Classification	0:13	Classification of Amazonian fast-growing tree species	0:52	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	0	39	theme	species	46:52	arg1	determination					72:84	wood chemical determination	58:84	wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS)	58:132	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	5	40	theme	universal	1122:1130	arg1	model					1136:1140	a three-species universal PLS model	1106:1140	a three-species universal PLS model to quantify the principal wood chemical components	1106:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	6	41	dep	models	1301:1306	arg1	RPD = 2.46					1261:1270	RPD = 2.46	1261:1270	RPD = 2.46, [Formula: see text] = 0.83	1261:1298	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	0	42	theme	tree	41:44	arg1	species					46:52	Amazonian fast-growing tree species	18:52	Amazonian fast-growing tree species	18:52	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	1	43	theme	economic	280:287	arg1	importance					289:298	the economic importance	276:298	the economic importance in the Amazon Forest	276:319	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	2	44	theme	illegal	435:441	arg1	logging					443:449	illegal logging	435:449	illegal logging	435:449	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	3	45	theme	wood	586:589	arg1	species					591:597	wood species	586:597	wood species	586:597	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	4	46	theme	PLS-DA	764:769	arg1	models					771:776	PLS-DA models	764:776	PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%)	764:917	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	0	47	theme	wood	58:61	arg1	determination					72:84	wood chemical determination	58:84	wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS)	58:132	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	2	48	theme	breeding	493:500	arg1	programs					502:509	tree breeding programs	488:509	tree breeding programs	488:509	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	2	48	theme	breeding	493:500	arg1	composition					475:485	chemical composition	466:485	chemical composition (tree breeding programs)	466:510	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	3	49	theme	species	591:597	arg1	classification					568:581	the classification	564:581	the classification of wood species	564:597	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	2	50	dep	method	395:400	arg1	determine					456:464	determine	456:464	determine chemical composition (tree breeding programs)	456:510	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	2	50	dep	method	395:400	arg1	discriminate					405:416	discriminate	405:416	discriminate specie (to avoid illegal logging)	405:450	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	4	51	theme	wood	804:807	arg1	sensibility					884:894	sensibility	884:894	sensibility	884:894	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	51	theme	wood	804:807	arg1	species					809:815	wood species	804:815	wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%)	804:917	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	51	theme	wood	804:807	arg1	accuracy					857:864	accuracy	857:864	accuracy	857:864	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	51	theme	wood	804:807	arg1	specificity					867:877	specificity	867:877	specificity	867:877	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	51	theme	wood	804:807	arg1	0.84 ≤ R2 ≤ 0.91					818:833	0.84 ≤ R2 ≤ 0.91	818:833	0.84 ≤ R2 ≤ 0.91	818:833	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	4	51	theme	wood	804:807	arg1	0.12 ≤ RMSEP ≤ 0.20					836:854	0.12 ≤ RMSEP ≤ 0.20	836:854	0.12 ≤ RMSEP ≤ 0.20	836:854	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	6	52	theme	=	1293:1293	arg1	RPD = 2.46					1261:1270	RPD = 2.46	1261:1270	RPD = 2.46, [Formula: see text] = 0.83	1261:1298	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	7	53	dep	method	1497:1502	arg1	discriminate					1507:1518	discriminate	1507:1518	to discriminate wood species	1504:1531	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	7	53	dep	method	1497:1502	arg1	determine					1540:1548	determine	1540:1548	to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina	1537:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	6	54	dep	model	1350:1354	arg1	=					1389:1389	=	1389:1389	=	1389:1389	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	4	55	theme	related	1018:1024	arg1	peaks					1012:1016	IR peaks	1009:1016	IR peaks related to cellulose, lignin, and hemicellulose	1009:1064	Our results showed that PLS-DA models for the classification of wood species (0.84 ≤ R2 ≤ 0.91, 0.12 ≤ RMSEP ≤ 0.20, accuracy, specificity, and sensibility between 95.2 and 100%) were satisfied with the full spectra and the differentiation among these species based on IR peaks related to cellulose, lignin, and hemicellulose.					
37188729	1	56	contain	have	190:193	arg2	potential					199:207	the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites	195:369	the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites	195:369	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	1	56	contain	have	190:193	arg1	trees					148:152	Fast-growing trees	135:152	Fast-growing trees like Capirona, Bolaina, and Pashaco	135:188	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	7	57	from	composition	1568:1578	arg1	trees					1592:1596	juvenile trees	1583:1596	juvenile trees of Pashaco, Capirona, and Bolaina	1583:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	3	58	theme	universal	605:613	arg1	model					615:619	a universal model	603:619	a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics	603:737	This study aimed to validate a model for the classification of wood species and a universal model for the rapid determination of cellulose, hemicellulose, and lignin using FTIR spectroscopy coupled with chemometrics.					
37188729	6	59	dep	RPD = 3.43	1357:1366	arg1	see					1379:1381	see	1379:1381	see text	1379:1386	Lignin (RPD = 2.27, [Formula: see text] = 0.84) and hemicellulose (RPD = 2.46, [Formula: see text] = 0.83) models showed a good prediction, while cellulose model (RPD = 3.43, [Formula: see text] = 0.91) classified as efficient.					
37188729	5	60	theme	principal	1158:1166	arg1	components					1182:1191	the principal wood chemical components	1154:1191	the principal wood chemical components	1154:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	2	61	theme	chemical	466:473	arg1	programs					502:509	tree breeding programs	488:509	tree breeding programs	488:509	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	2	61	theme	chemical	466:473	arg1	composition					475:485	chemical composition	466:485	chemical composition (tree breeding programs)	466:510	Therefore, a practical method to discriminate specie (to avoid illegal logging) and determine chemical composition (tree breeding programs) is needed.					
37188729	5	62	theme	chemical	1173:1180	arg1	components					1182:1191	the principal wood chemical components	1154:1191	the principal wood chemical components	1154:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	7	63	theme	juvenile	1583:1590	arg1	trees					1592:1596	juvenile trees	1583:1596	juvenile trees of Pashaco, Capirona, and Bolaina	1583:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	5	64	theme	wood	1168:1171	arg1	components					1182:1191	the principal wood chemical components	1154:1191	the principal wood chemical components	1154:1191	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	0	65	theme	chemical	63:70	arg1	determination					72:84	wood chemical determination	58:84	wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS)	58:132	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	5	66	theme	full	1080:1083	arg1	spectra					1085:1091	the full spectra	1076:1091	the full spectra	1076:1091	Besides, the full spectra helped build a three-species universal PLS model to quantify the principal wood chemical components.					
37188729	0	67	theme	Amazonian	18:26	arg1	species					46:52	Amazonian fast-growing tree species	18:52	Amazonian fast-growing tree species	18:52	Classification of Amazonian fast-growing tree species and wood chemical determination by FTIR and multivariate analysis (PLS-DA, PLS).					
37188729	1	68	theme	Fast-growing	135:146	arg1	trees					148:152	Fast-growing trees	135:152	Fast-growing trees like Capirona, Bolaina, and Pashaco	135:188	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37188729	7	69	theme	chemical	1559:1566	arg1	composition					1568:1578	the wood chemical composition	1550:1578	the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina	1550:1630	This study showed that FTIR-ATR, together with chemometrics, is a reliable method to discriminate wood species and to determine the wood chemical composition in juvenile trees of Pashaco, Capirona, and Bolaina.					
37188729	1	70	theme	forest	219:224	arg1	degradation					226:236	forest degradation	219:236	forest degradation	219:236	Fast-growing trees like Capirona, Bolaina, and Pashaco have the potential to reduce forest degradation because of their ecological features, the economic importance in the Amazon Forest, and an industry based on wood-polymer composites.					
37270158	1	0	theme	responsible	231:241	arg1	component					221:229	the component	217:229	the component responsible for degradation by human microbiota	217:277	Inulin has been applied in Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota.					
37270158	10	1	theme	RS	1505:1506	arg1	ratio					1514:1518	Eudragit RS blend ratio	1496:1518	Eudragit RS blend ratio	1496:1518	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	9	2	theme	caffeine	1372:1379	arg1	permeation					1343:1352	The permeation	1339:1352	The permeation of the model drug caffeine	1339:1379	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	6	3	theme	permeability	866:877	arg1	coefficient					879:889	the permeability coefficient	862:889	the permeability coefficient of caffeine	862:901	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	7	4	theme	Inu-ERS	1079:1085	arg1	films					1087:1091	the Inu-ERS films	1075:1091	the Inu-ERS films with and without incubation in the enzyme solution	1075:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	0	5	theme	New	0:2	arg1	insights					4:11	New insights	0:11	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.	0:147	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	10	6	theme	water	1694:1698	arg1	channels					1700:1707	the formed water channels	1683:1707	the formed water channels	1683:1707	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	9	7	theme	phase-separated	1397:1411	arg1	film					1413:1416	the phase-separated film	1393:1416	the phase-separated film	1393:1416	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	4	8	theme	inulin	617:622	arg1	ratio					608:612	The ratio	604:612	The ratio of inulin to Eudragit RS	604:637	The ratio of inulin to Eudragit RS was varied to create films with different degree of hydrophilicity.					
37270158	7	9	theme	morphology	1044:1053	arg1	characterization					1055:1070	the morphology characterization	1040:1070	the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution	1040:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	3	10	theme	molecular	550:558	arg1	weights					560:566	various molecular weights	542:566	various molecular weights in isolated films with Eudragit RS	542:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	1	11	theme	RS	192:193	arg1	coatings					205:212	Inulin-Eudragit RS (Inu-ERS) coatings	176:212	Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota	176:277	Inulin has been applied in Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota.					
37270158	4	12	theme	Eudragit	627:634	arg1	RS					636:637	Eudragit RS	627:637	Eudragit RS	627:637	The ratio of inulin to Eudragit RS was varied to create films with different degree of hydrophilicity.					
37270158	10	13	theme	inulin	1548:1553	arg1	ratio					1514:1518	Eudragit RS blend ratio	1496:1518	Eudragit RS blend ratio	1496:1518	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	13	theme	inulin	1548:1553	arg1	weight					1538:1543	the molecular weight	1524:1543	the molecular weight of inulin	1524:1553	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	9	14	theme	model	1361:1365	arg1	caffeine					1372:1379	the model drug caffeine	1357:1379	the model drug caffeine	1357:1379	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	3	15	theme	Eudragit	591:598	arg1	RS					600:601	Eudragit RS	591:601	Eudragit RS	591:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	1	16	theme	Inu-ERS	196:202	arg1	coatings					205:212	Inulin-Eudragit RS (Inu-ERS) coatings	176:212	Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota	176:277	Inulin has been applied in Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota.					
37270158	6	17	theme	inulin	923:928	arg1	fraction					911:918	the fraction	907:918	the fraction of inulin that was released from the films in a buffer solution with or without inulinase	907:1008	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	0	18	theme	drug	134:137	arg1	delivery					139:146	colon drug delivery	128:146	colon drug delivery	128:146	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	9	19	theme	pores	1433:1437	arg1	result					1423:1428	a result	1421:1428	a result of pores formed as a consequence of inulin release	1421:1479	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	10	20	theme	drug	1731:1734	arg1	properties					1747:1756	the drug permeation properties	1727:1756	the drug permeation properties	1727:1756	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	4	21	theme	different	671:679	arg1	degree					681:686	different degree	671:686	different degree of hydrophilicity	671:704	The ratio of inulin to Eudragit RS was varied to create films with different degree of hydrophilicity.					
37270158	9	22	theme	inulin	1466:1471	arg1	release					1473:1479	inulin release	1466:1479	inulin release	1466:1479	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	3	23	with	films	580:584	arg1	RS					600:601	Eudragit RS	591:601	Eudragit RS	591:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	8	24	theme	RS	1311:1312	arg1	matrix					1314:1319	the Eudragit RS matrix	1298:1319	the Eudragit RS matrix	1298:1319	Inulin fully embedded in the Eudragit RS matrix was not degraded.					
37270158	2	25	theme	insoluble	380:388	arg1	polymers					390:397	water insoluble polymers	374:397	water insoluble polymers like Eudragit RS	374:414	However, studies on how bacterial enzymes can degrade polysaccharides like inulin imbedded in water insoluble polymers like Eudragit RS are still elusive.					
37270158	0	26	theme	Inulin-Eudragit	91:105	arg1	coatings					115:122	Inulin-Eudragit RS film coatings	91:122	Inulin-Eudragit RS film coatings	91:122	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	3	27	with	biodegradation	512:525	arg1	weights					560:566	various molecular weights	542:566	various molecular weights in isolated films with Eudragit RS	542:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	8	28	from	embedded	1286:1293	arg1	matrix					1314:1319	the Eudragit RS matrix	1298:1319	the Eudragit RS matrix	1298:1319	Inulin fully embedded in the Eudragit RS matrix was not degraded.					
37270158	0	29	from	effects	20:26	arg1	biodegradation					56:69	biodegradation	56:69	biodegradation	56:69	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	0	29	from	effects	20:26	arg1	permeability					75:86	permeability	75:86	permeability	75:86	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	10	30	theme	percolation	1568:1578	arg1	threshold					1580:1588	the percolation threshold	1564:1588	the percolation threshold	1564:1588	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	5	31	theme	phase	783:787	arg1	blends					746:751	blends	746:751	blends of inulin and Eudragit RS	746:777	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	5	31	theme	phase	783:787	arg1	systems					799:805	phase separated systems	783:805	phase separated systems	783:805	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	0	32	dep	biodegradation	56:69	arg1	the					52:54	the	52:54	the	52:54	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	10	33	theme	inulin	1606:1611	arg1	threshold					1580:1588	the percolation threshold	1564:1588	the percolation threshold	1564:1588	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	33	theme	inulin	1606:1611	arg1	morphology					1618:1627	the morphology	1614:1627	the morphology of the film formed thereafter	1614:1657	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	33	theme	inulin	1606:1611	arg1	connectivity					1667:1678	the connectivity	1663:1678	the connectivity of the formed water channels	1663:1707	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	33	theme	inulin	1606:1611	arg1	release					1595:1601	the release	1591:1601	the release of inulin	1591:1611	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	7	34	theme	enzyme	1128:1133	arg1	solution					1135:1142	the enzyme solution	1124:1142	the enzyme solution	1124:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	5	35	theme	RS	776:777	arg1	blends					746:751	blends	746:751	blends of inulin and Eudragit RS	746:777	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	5	35	theme	RS	776:777	arg1	systems					799:805	phase separated systems	783:805	phase separated systems	783:805	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	6	36	attach	released	939:946	arg1	films					957:961	the films	953:961	the films in a buffer solution with or without inulinase	953:1008	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	6	36	attach	released	939:946	arg2	inulin					923:928	inulin	923:928	inulin that was released from the films in a buffer solution with or without inulinase	923:1008	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	2	37	theme	bacterial	304:312	arg1	enzymes					314:320	bacterial enzymes	304:320	bacterial enzymes	304:320	However, studies on how bacterial enzymes can degrade polysaccharides like inulin imbedded in water insoluble polymers like Eudragit RS are still elusive.					
37270158	3	38	theme	enzyme	495:500	arg1	biodegradation					512:525	enzyme triggered biodegradation	495:525	enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS	495:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	5	39	theme	Eudragit	767:774	arg1	RS					776:777	Eudragit RS	767:777	Eudragit RS	767:777	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	10	40	theme	film	1636:1639	arg1	threshold					1580:1588	the percolation threshold	1564:1588	the percolation threshold	1564:1588	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	40	theme	film	1636:1639	arg1	morphology					1618:1627	the morphology	1614:1627	the morphology of the film formed thereafter	1614:1657	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	40	theme	film	1636:1639	arg1	connectivity					1667:1678	the connectivity	1663:1678	the connectivity of the formed water channels	1663:1707	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	40	theme	film	1636:1639	arg1	release					1595:1601	the release	1591:1601	the release of inulin	1591:1611	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	6	41	theme	caffeine	894:901	arg1	coefficient					879:889	the permeability coefficient	862:889	the permeability coefficient of caffeine	862:901	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	10	42	theme	blend	1508:1512	arg1	ratio					1514:1518	Eudragit RS blend ratio	1496:1518	Eudragit RS blend ratio	1496:1518	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	7	43	theme	films	1087:1091	arg1	characterization					1055:1070	the morphology characterization	1040:1070	the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution	1040:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	3	44	theme	inulin	530:535	arg1	biodegradation					512:525	enzyme triggered biodegradation	495:525	enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS	495:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	8	45	from	matrix	1314:1319	arg1	embedded					1286:1293	embedded	1286:1293	embedded	1286:1293	Inulin fully embedded in the Eudragit RS matrix was not degraded.					
37270158	9	46	theme	drug	1367:1370	arg1	caffeine					1372:1379	the model drug caffeine	1357:1379	the model drug caffeine	1357:1379	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	6	47	theme	coefficient	879:889	arg1	determination					845:857	determination	845:857	determination of the permeability coefficient of caffeine	845:901	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	8	48	theme	embedded	1286:1293	arg1	Inulin					1273:1278	Inulin	1273:1278	Inulin fully embedded in the Eudragit RS matrix	1273:1319	Inulin fully embedded in the Eudragit RS matrix was not degraded.					
37270158	10	49	theme	Eudragit	1496:1503	arg1	ratio					1514:1518	Eudragit RS blend ratio	1496:1518	Eudragit RS blend ratio	1496:1518	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	3	50	theme	biodegradation	512:525	arg1	process					484:490	the complex process	472:490	the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS	472:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	0	51	theme	blend	31:35	arg1	composition					37:47	blend composition	31:47	blend composition	31:47	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	10	52	theme	molecular	1528:1536	arg1	weight					1538:1543	the molecular weight	1524:1543	the molecular weight of inulin	1524:1553	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	53	theme	channels	1700:1707	arg1	threshold					1580:1588	the percolation threshold	1564:1588	the percolation threshold	1564:1588	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	53	theme	channels	1700:1707	arg1	morphology					1618:1627	the morphology	1614:1627	the morphology of the film formed thereafter	1614:1657	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	53	theme	channels	1700:1707	arg1	connectivity					1667:1678	the connectivity	1663:1678	the connectivity of the formed water channels	1663:1707	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	10	53	theme	channels	1700:1707	arg1	release					1595:1601	the release	1591:1601	the release of inulin	1591:1611	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	0	54	theme	coatings	115:122	arg1	biodegradation					56:69	biodegradation	56:69	biodegradation	56:69	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	0	54	theme	coatings	115:122	arg1	permeability					75:86	permeability	75:86	permeability	75:86	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	3	55	theme	various	542:548	arg1	weights					560:566	various molecular weights	542:566	various molecular weights in isolated films with Eudragit RS	542:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	1	56	theme	Inulin-Eudragit	176:190	arg1	coatings					205:212	Inulin-Eudragit RS (Inu-ERS) coatings	176:212	Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota	176:277	Inulin has been applied in Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota.					
37270158	0	57	theme	colon	128:132	arg1	delivery					139:146	colon drug delivery	128:146	colon drug delivery	128:146	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	3	58	theme	isolated	571:578	arg1	films					580:584	isolated films	571:584	isolated films with Eudragit RS	571:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	10	59	theme	formed	1687:1692	arg1	channels					1700:1707	the formed water channels	1683:1707	the formed water channels	1683:1707	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	4	60	theme	hydrophilicity	691:704	arg1	degree					681:686	different degree	671:686	different degree of hydrophilicity	671:704	The ratio of inulin to Eudragit RS was varied to create films with different degree of hydrophilicity.					
37270158	3	61	from	weights	560:566	arg1	films					580:584	isolated films	571:584	isolated films with Eudragit RS	571:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	7	62	theme	enzyme	1190:1195	arg1	action					1176:1181	the action	1172:1181	the action of the enzyme	1172:1195	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	7	62	theme	enzyme	1190:1195	arg1	limited					1206:1212	limited	1206:1212	limited	1206:1212	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	10	63	theme	permeation	1736:1745	arg1	properties					1747:1756	the drug permeation properties	1727:1756	the drug permeation properties	1727:1756	The inulin to Eudragit RS blend ratio and the molecular weight of inulin affected the percolation threshold, the release of inulin, the morphology of the film formed thereafter and the connectivity of the formed water channels, thus influencing the drug permeation properties.					
37270158	5	64	theme	phase	711:715	arg1	study					726:730	The phase behavior study	707:730	The phase behavior study	707:730	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	6	65	theme	buffer	968:973	arg1	solution					975:982	a buffer solution	966:982	a buffer solution with or without inulinase	966:1008	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	0	66	theme	film	110:113	arg1	coatings					115:122	Inulin-Eudragit RS film coatings	91:122	Inulin-Eudragit RS film coatings	91:122	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	0	67	from	insights	4:11	arg1	effects					20:26	the effects	16:26	the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery	16:146	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	9	68	theme	release	1473:1479	arg1	consequence					1451:1461	a consequence	1449:1461	a consequence of inulin release	1449:1479	The permeation of the model drug caffeine occurred in the phase-separated film as a result of pores formed as a consequence of inulin release.					
37270158	7	69	from	solution	1135:1142	arg1	characterization					1055:1070	the morphology characterization	1040:1070	the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution	1040:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	0	70	theme	RS	107:108	arg1	coatings					115:122	Inulin-Eudragit RS film coatings	91:122	Inulin-Eudragit RS film coatings	91:122	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	6	71	from	films	957:961	arg1	solution					975:982	a buffer solution	966:982	a buffer solution with or without inulinase	966:1008	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	8	72	theme	Eudragit	1302:1309	arg1	matrix					1314:1319	the Eudragit RS matrix	1298:1319	the Eudragit RS matrix	1298:1319	Inulin fully embedded in the Eudragit RS matrix was not degraded.					
37270158	2	73	theme	water	374:378	arg1	polymers					390:397	water insoluble polymers	374:397	water insoluble polymers like Eudragit RS	374:414	However, studies on how bacterial enzymes can degrade polysaccharides like inulin imbedded in water insoluble polymers like Eudragit RS are still elusive.					
37270158	7	74	from	characterization	1055:1070	arg1	solution					1135:1142	the enzyme solution	1124:1142	the enzyme solution	1124:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	5	75	theme	separated	789:797	arg1	blends					746:751	blends	746:751	blends of inulin and Eudragit RS	746:777	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	5	75	theme	separated	789:797	arg1	systems					799:805	phase separated systems	783:805	phase separated systems	783:805	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	1	76	theme	human	262:266	arg1	microbiota					268:277	human microbiota	262:277	human microbiota	262:277	Inulin has been applied in Inulin-Eudragit RS (Inu-ERS) coatings as the component responsible for degradation by human microbiota.					
37270158	7	77	theme	buffer	1256:1261	arg1	solution					1263:1270	the buffer solution	1252:1270	the buffer solution	1252:1270	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	2	78	theme	Eudragit	404:411	arg1	RS					413:414	Eudragit RS	404:414	Eudragit RS	404:414	However, studies on how bacterial enzymes can degrade polysaccharides like inulin imbedded in water insoluble polymers like Eudragit RS are still elusive.					
37270158	5	79	theme	inulin	756:761	arg1	blends					746:751	blends	746:751	blends of inulin and Eudragit RS	746:777	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	5	79	theme	inulin	756:761	arg1	systems					799:805	phase separated systems	783:805	phase separated systems	783:805	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	7	80	from	films	1087:1091	arg1	solution					1135:1142	the enzyme solution	1124:1142	the enzyme solution	1124:1142	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	3	81	theme	present	439:445	arg1	work					447:450	The present work	435:450	The present work	435:450	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	0	82	theme	composition	37:47	arg1	effects					20:26	the effects	16:26	the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery	16:146	New insights on the effects of blend composition on the biodegradation and permeability of Inulin-Eudragit RS film coatings for colon drug delivery.					
37270158	7	83	theme	inulin	1233:1238	arg1	fraction					1221:1228	the fraction	1217:1228	the fraction of inulin released in the buffer solution	1217:1270	Together with the morphology characterization of the Inu-ERS films with and without incubation in the enzyme solution, these results suggest that the action of the enzyme was only limited to the fraction of inulin released in the buffer solution.					
37270158	3	84	theme	complex	476:482	arg1	process					484:490	the complex process	472:490	the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS	472:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
37270158	6	85	theme	film	812:815	arg1	permeability					817:828	The film permeability	808:828	The film permeability	808:828	The film permeability was studied by determination of the permeability coefficient of caffeine and the fraction of inulin that was released from the films in a buffer solution with or without inulinase was quantified.					
37270158	5	86	theme	behavior	717:724	arg1	study					726:730	The phase behavior study	707:730	The phase behavior study	707:730	The phase behavior study revealed that blends of inulin and Eudragit RS are phase separated systems.					
37270158	3	87	theme	triggered	502:510	arg1	biodegradation					512:525	enzyme triggered biodegradation	495:525	enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS	495:601	The present work aims at elucidating the complex process of enzyme triggered biodegradation of inulin with various molecular weights in isolated films with Eudragit RS.					
35122797	0	0	theme	acrylate	85:92	arg1	copolymer					94:102	benzyl acrylate copolymer	78:102	benzyl acrylate copolymer	78:102	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	5	1	theme	absorption	809:818	arg1	region					820:825	the ultraviolet absorption region	793:825	the ultraviolet absorption region	793:825	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	3	2	theme	UV	500:501	arg1	ability					512:518	UV blocking ability	500:518	UV blocking ability	500:518	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	7	3	from	potentials	1150:1159	arg1	fields					1170:1175	broad fields	1164:1175	broad fields	1164:1175	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	3	from	potentials	1150:1159	arg1	protection					1213:1222	medical protection	1205:1222	medical protection	1205:1222	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	3	from	potentials	1150:1159	arg1	applications					1245:1256	surface coating applications	1229:1256	surface coating applications	1229:1256	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	3	from	potentials	1150:1159	arg1	preservation					1191:1202	food preservation	1186:1202	food preservation	1186:1202	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	0	4	theme	benzyl	78:83	arg1	copolymer					94:102	benzyl acrylate copolymer	78:102	benzyl acrylate copolymer	78:102	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	0	5	from	adjustment	7:16	arg1	cellulose					21:29	cellulose	21:29	cellulose	21:29	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	7	6	theme	nanocomposite	1091:1103	arg1	films					1105:1109	The nanocomposite films	1087:1109	The nanocomposite films proposed in this work	1087:1131	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	6	7	theme	pure	1071:1074	arg1	film					1081:1084	pure CNCs film	1071:1084	pure CNCs film	1071:1084	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	3	8	theme	blocking	503:510	arg1	ability					512:518	UV blocking ability	500:518	UV blocking ability	500:518	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	6	9	theme	BACNC	964:968	arg1	film					970:973	BACNC film	964:973	BACNC film	964:973	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	7	10	theme	surface	1229:1235	arg1	applications					1245:1256	surface coating applications	1229:1256	surface coating applications	1229:1256	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	4	11	theme	280-320 nm	723:732	arg1	region					735:740	UVB (280-320 nm) region	718:740	UVB (280-320 nm) region	718:740	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	7	12	theme	broad	1164:1168	arg1	fields					1170:1175	broad fields	1164:1175	broad fields	1164:1175	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	12	theme	broad	1164:1168	arg1	protection					1213:1222	medical protection	1205:1222	medical protection	1205:1222	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	12	theme	broad	1164:1168	arg1	applications					1245:1256	surface coating applications	1229:1256	surface coating applications	1229:1256	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	12	theme	broad	1164:1168	arg1	preservation					1191:1202	food preservation	1186:1202	food preservation	1186:1202	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	7	13	theme	medical	1205:1211	arg1	protection					1213:1222	medical protection	1205:1222	medical protection	1205:1222	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	3	14	theme	thermal	545:551	arg1	properties					553:562	thermal properties	545:562	thermal properties	545:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	5	15	theme	nematic	903:909	arg1	structure					911:919	the original chiral nematic structure	883:919	the original chiral nematic structure of the films	883:932	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	0	16	theme	UV	117:118	arg1	property					130:137	enhanced UV shielding property	108:137	enhanced UV shielding property	108:137	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	7	17	theme	coating	1237:1243	arg1	applications					1245:1256	surface coating applications	1229:1256	surface coating applications	1229:1256	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	3	18	theme	modified	460:467	arg1	films					484:488	modified CNCs composite films	460:488	modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties	460:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	18	theme	modified	460:467	arg1	ability					512:518	UV blocking ability	500:518	UV blocking ability	500:518	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	18	theme	modified	460:467	arg1	strength					532:539	mechanical strength	521:539	mechanical strength	521:539	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	18	theme	modified	460:467	arg1	properties					553:562	thermal properties	545:562	thermal properties	545:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	19	theme	mechanical	521:530	arg1	strength					532:539	mechanical strength	521:539	mechanical strength	521:539	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	5	20	theme	95.49	845:849	arg1	%					840:840	%	840:840	%	840:840	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	1	21	theme	cellulose	161:169	arg1	CNCs					185:188	CNCs	185:188	CNCs	185:188	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	1	21	theme	cellulose	161:169	arg1	nanocrystals					171:182	cellulose nanocrystals	161:182	cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities	161:243	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	0	22	theme	enhanced	108:115	arg1	property					130:137	enhanced UV shielding property	108:137	enhanced UV shielding property	108:137	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	6	23	theme	mechanical	988:997	arg1	properties					999:1008	the mechanical properties	984:1008	the mechanical properties	984:1008	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	6	24	dep	strength	1034:1041	arg1	times					1046:1050	times	1046:1050	times	1046:1050	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	5	25	theme	film	785:788	arg1	performance					757:767	The shielding performance	743:767	The shielding performance of the modified film in the ultraviolet absorption region	743:825	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	5	26	theme	shielding	747:755	arg1	performance					757:767	The shielding performance	743:767	The shielding performance of the modified film in the ultraviolet absorption region	743:825	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	6	27	theme	16	1043:1044	arg1	times					1046:1050	times	1046:1050	times	1046:1050	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	4	28	theme	shielding	668:676	arg1	property					678:685	good UV shielding property	660:685	good UV shielding property	660:685	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	28	theme	shielding	668:676	arg1	result					627:632	a result	625:632	a result	625:632	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	0	29	theme	Facile	0:5	arg1	adjustment					7:16	Facile adjustment	0:16	Facile adjustment on cellulose	0:29	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	4	30	theme	UVB	718:720	arg1	region					735:740	UVB (280-320 nm) region	718:740	UVB (280-320 nm) region	718:740	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	2	31	theme	morphological	346:358	arg1	variations					360:369	Chemical and morphological variations	333:369	Chemical and morphological variations during the fabrication of the films	333:405	Chemical and morphological variations during the fabrication of the films were systematically characterized.					
35122797	1	32	with	films	201:205	arg1	capabilities					232:243	suitable applicable capabilities	212:243	suitable applicable capabilities	212:243	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	1	33	dep	nanocrystals	171:182	arg1	films					201:205	composite films	191:205	cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities	161:243	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	2	34	theme	films	401:405	arg1	fabrication					382:392	the fabrication	378:392	the fabrication of the films	378:405	Chemical and morphological variations during the fabrication of the films were systematically characterized.					
35122797	5	35	theme	ultraviolet	797:807	arg1	region					820:825	the ultraviolet absorption region	793:825	the ultraviolet absorption region	793:825	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	0	36	theme	shielding	120:128	arg1	property					130:137	enhanced UV shielding property	108:137	enhanced UV shielding property	108:137	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	4	37	theme	UVC	690:692	arg1	region					707:712	UVC (220-280 nm) region	690:712	UVC (220-280 nm) region	690:712	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	1	38	theme	composite	191:199	arg1	films					201:205	composite films	191:205	cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities	161:243	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	0	39	theme	composite	44:52	arg1	films					54:58	composite films	44:58	composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property	44:137	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	5	40	theme	original	887:894	arg1	structure					911:919	the original chiral nematic structure	883:919	the original chiral nematic structure of the films	883:932	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	3	41	theme	applicable	599:608	arg1	potentials					610:619	their applicable potentials	593:619	their applicable potentials	593:619	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	4	42	theme	UV	665:666	arg1	property					678:685	good UV shielding property	660:685	good UV shielding property	660:685	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	42	theme	UV	665:666	arg1	result					627:632	a result	625:632	a result	625:632	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	43	theme	good	660:663	arg1	property					678:685	good UV shielding property	660:685	good UV shielding property	660:685	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	43	theme	good	660:663	arg1	result					627:632	a result	625:632	a result	625:632	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	1	44	dep	suitable	212:219	arg1	applicable					221:230	applicable	221:230	applicable	221:230	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	4	45	theme	composite	639:647	arg1	films					649:653	the composite films	635:653	the composite films	635:653	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	5	46	dep	%	840:840	arg1	to					842:843	to	842:843	to	842:843	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	6	47	theme	CNCs	1076:1079	arg1	film					1081:1084	pure CNCs film	1071:1084	pure CNCs film	1071:1084	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	3	48	theme	films	484:488	arg1	properties					446:455	The properties	442:455	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties	442:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	5	49	theme	modified	776:783	arg1	film					785:788	the modified film	772:788	the modified film	772:788	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	6	50	dep	times	1046:1050	arg1	higher					1052:1057	higher	1052:1057	higher	1052:1057	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	1	51	theme	present	147:153	arg1	work					155:158	the present work	143:158	the present work	143:158	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	4	52	theme	220-280 nm	695:704	arg1	region					707:712	UVC (220-280 nm) region	690:712	UVC (220-280 nm) region	690:712	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	1	53	theme	benzyl	309:314	arg1	poly					304:307	poly	304:307	poly(benzyl acrylate) (PBA)	304:330	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	1	53	theme	benzyl	309:314	arg1	acrylate					316:323	benzyl acrylate	309:323	benzyl acrylate	309:323	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	7	54	theme	promising	1140:1148	arg1	potentials					1150:1159	promising potentials	1140:1159	promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications	1140:1256	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	3	55	theme	CNCs	469:472	arg1	films					484:488	modified CNCs composite films	460:488	modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties	460:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	55	theme	CNCs	469:472	arg1	ability					512:518	UV blocking ability	500:518	UV blocking ability	500:518	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	55	theme	CNCs	469:472	arg1	strength					532:539	mechanical strength	521:539	mechanical strength	521:539	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	55	theme	CNCs	469:472	arg1	properties					553:562	thermal properties	545:562	thermal properties	545:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	1	56	theme	suitable	212:219	arg1	capabilities					232:243	suitable applicable capabilities	212:243	suitable applicable capabilities	212:243	In the present work, cellulose nanocrystals (CNCs) composite films with suitable applicable capabilities were prepared by facilely incorporating glycerol (Gly) and poly(benzyl acrylate) (PBA).					
35122797	4	57	contain	have	655:658	arg2	result					627:632	a result	625:632	a result	625:632	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	57	contain	have	655:658	arg2	property					678:685	good UV shielding property	660:685	good UV shielding property	660:685	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	4	57	contain	have	655:658	arg1	films					649:653	the composite films	635:653	the composite films	635:653	As a result, the composite films have good UV shielding property in UVC (220-280 nm) region and UVB (280-320 nm) region.					
35122797	6	58	theme	tensile	1026:1032	arg1	strength					1034:1041	the tensile strength	1022:1041	the tensile strength 16 times higher	1022:1057	Along with the modification, BACNC film improved the mechanical properties, presenting the tensile strength 16 times higher compared to pure CNCs film.					
35122797	3	59	theme	composite	474:482	arg1	films					484:488	modified CNCs composite films	460:488	modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties	460:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	59	theme	composite	474:482	arg1	ability					512:518	UV blocking ability	500:518	UV blocking ability	500:518	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	59	theme	composite	474:482	arg1	strength					532:539	mechanical strength	521:539	mechanical strength	521:539	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	3	59	theme	composite	474:482	arg1	properties					553:562	thermal properties	545:562	thermal properties	545:562	The properties of modified CNCs composite films including UV blocking ability, mechanical strength and thermal properties were characterized to assess their applicable potentials.					
35122797	5	60	theme	chiral	896:901	arg1	structure					911:919	the original chiral nematic structure	883:919	the original chiral nematic structure of the films	883:932	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	7	61	theme	food	1186:1189	arg1	preservation					1191:1202	food preservation	1186:1202	food preservation	1186:1202	The nanocomposite films proposed in this work showed promising potentials in broad fields, such as food preservation, medical protection, and surface coating applications.					
35122797	5	62	theme	92.77	835:839	arg1	%					840:840	%	840:840	%	840:840	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	0	63	with	films	54:58	arg1	glycerol					65:72	glycerol	65:72	glycerol	65:72	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	0	63	with	films	54:58	arg1	copolymer					94:102	benzyl acrylate copolymer	78:102	benzyl acrylate copolymer	78:102	Facile adjustment on cellulose nanocrystals composite films with glycerol and benzyl acrylate copolymer for enhanced UV shielding property.					
35122797	5	64	theme	films	928:932	arg1	structure					911:919	the original chiral nematic structure	883:919	the original chiral nematic structure of the films	883:932	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	5	65	from	performance	757:767	arg1	region					820:825	the ultraviolet absorption region	793:825	the ultraviolet absorption region	793:825	The shielding performance of the modified film in the ultraviolet absorption region reached 92.77% to 95.49% respectively, without damaging the original chiral nematic structure of the films.					
35122797	2	66	theme	Chemical	333:340	arg1	variations					360:369	Chemical and morphological variations	333:369	Chemical and morphological variations during the fabrication of the films	333:405	Chemical and morphological variations during the fabrication of the films were systematically characterized.					
35630579	0	0	theme	Potato	62:67	arg1	Starch					69:74	Sweet Potato Starch	56:74	Sweet Potato Starch	56:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	1	1	theme	plant-based	273:283	arg1	rinds					290:294	plant-based pork rinds	273:294	plant-based pork rinds	273:294	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	6	2	theme	compact	1113:1119	arg1	structure					1125:1133	a more compact gel structure	1106:1133	a more compact gel structure	1106:1133	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	2	3	theme	Plant-based	297:307	arg1	gels					309:312	Plant-based gels	297:312	Plant-based gels	297:312	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	8	4	theme	pork	1465:1468	arg1	rinds					1470:1474	plant-based pork rinds	1453:1474	plant-based pork rinds	1453:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	7	5	theme	similar	1282:1288	arg1	rinds					1306:1310	the most similar to natural pork rinds	1273:1310	the most similar to natural pork rinds	1273:1310	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	0	6	theme	Sweet	56:60	arg1	Starch					69:74	Sweet Potato Starch	56:74	Sweet Potato Starch	56:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	1	7	theme	pork	285:288	arg1	rinds					290:294	plant-based pork rinds	273:294	plant-based pork rinds	273:294	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	4	8	theme	pork	761:764	arg1	rinds					766:770	natural pork rinds	753:770	natural pork rinds	753:770	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	8	9	theme	soybean	1587:1593	arg1	oil					1595:1597	soybean oil	1587:1597	soybean oil	1587:1597	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	1	10	theme	sweet	138:142	arg1	SPS					159:161	SPS	159:161	SPS	159:161	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	10	theme	sweet	138:142	arg1	starch					151:156	sweet potato starch	138:156	sweet potato starch (SPS)	138:162	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	8	11	theme	schematic	1408:1416	arg1	model					1418:1422	a possible schematic model	1397:1422	a possible schematic model for the gelling mechanism of plant-based pork rinds	1397:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	1	12	theme	rinds	290:294	arg1	textural					200:207	textural	200:207	textural	200:207	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	6	13	theme	scanning	1011:1018	arg1	SEM					1041:1043	SEM	1041:1043	SEM	1041:1043	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	6	13	theme	scanning	1011:1018	arg1	microscopy					1029:1038	scanning electron microscopy	1011:1038	scanning electron microscopy (SEM)	1011:1044	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	3	14	theme	profile	461:467	arg1	TPA					479:481	TPA	479:481	TPA	479:481	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	3	14	theme	profile	461:467	arg1	analysis					469:476	texture profile analysis	453:476	The texture profile analysis (TPA) results	449:490	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	7	15	theme	%	1242:1242	arg1	samples					1248:1254	the 0.4% KGM samples	1235:1254	the 0.4% KGM samples	1235:1254	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	8	16	theme	KGM	1622:1624	arg1	addition					1610:1617	the addition	1606:1617	the addition of KGM and NaHCO3	1606:1635	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	0	17	theme	Starch	69:74	arg1	Rinds					11:15	Pork Rinds	6:15	Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan	6:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	17	theme	Starch	69:74	arg1	Influence					43:51	The Influence	39:51	The Influence of Sweet Potato Starch	39:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	5	18	theme	adding	869:874	arg1	SPS					876:878	SPS	876:878	SPS	876:878	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	3	19	theme	analysis	469:476	arg1	results					484:490	The texture profile analysis (TPA) results	449:490	The texture profile analysis (TPA) results	449:490	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	8	20	theme	network	1499:1505	arg1	structures					1507:1516	the three-dimensional network structures	1477:1516	the three-dimensional network structures of the samples	1477:1531	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	2	21	theme	KGM	429:431	arg1	concentrations					433:446	KGM concentrations	429:446	KGM concentrations	429:446	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	1	22	from	effect	128:133	arg1	textural					200:207	textural	200:207	textural	200:207	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	22	from	effect	128:133	arg1	microstructures					254:268	microstructures	254:268	microstructures	254:268	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	22	from	effect	128:133	arg1	sensory					217:223	sensory	217:223	sensory	217:223	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	22	from	effect	128:133	arg1	properties					238:247	rheological properties	226:247	rheological properties	226:247	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	22	from	effect	128:133	arg1	color					210:214	color	210:214	color	210:214	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	6	23	theme	electron	1020:1027	arg1	SEM					1041:1043	SEM	1041:1043	SEM	1041:1043	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	6	23	theme	electron	1020:1027	arg1	microscopy					1029:1038	scanning electron microscopy	1011:1038	scanning electron microscopy (SEM)	1011:1044	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	8	24	theme	three-dimensional	1481:1497	arg1	structures					1507:1516	the three-dimensional network structures	1477:1516	the three-dimensional network structures of the samples	1477:1531	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	1	25	theme	potato	144:149	arg1	SPS					159:161	SPS	159:161	SPS	159:161	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	25	theme	potato	144:149	arg1	starch					151:156	sweet potato starch	138:156	sweet potato starch (SPS)	138:162	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	0	26	from	Gel	34:36	arg1	Rinds					11:15	Pork Rinds	6:15	Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan	6:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	26	from	Gel	34:36	arg1	Influence					43:51	The Influence	39:51	The Influence of Sweet Potato Starch	39:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	26	from	Gel	34:36	arg1	Glucomannan					87:97	Glucomannan	87:97	Glucomannan	87:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	3	27	theme	texture	453:459	arg1	TPA					479:481	TPA	479:481	TPA	479:481	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	3	27	theme	texture	453:459	arg1	analysis					469:476	texture profile analysis	453:476	The texture profile analysis (TPA) results	449:490	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	1	28	theme	starch	151:156	arg1	effect					128:133	the effect	124:133	the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds	124:294	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	0	29	theme	Pork	6:9	arg1	Rinds					11:15	Pork Rinds	6:15	Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan	6:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	29	theme	Pork	6:9	arg1	Influence					43:51	The Influence	39:51	The Influence of Sweet Potato Starch	39:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	29	theme	Pork	6:9	arg1	Glucomannan					87:97	Glucomannan	87:97	Glucomannan	87:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	4	30	theme	natural	753:759	arg1	rinds					766:770	natural pork rinds	753:770	natural pork rinds	753:770	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	7	31	theme	SPS	1219:1221	arg1	samples					1223:1229	the 40% SPS samples	1211:1229	the 40% SPS samples	1211:1229	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	7	32	theme	mathematical	1138:1149	arg1	model					1151:1155	A mathematical model	1136:1155	A mathematical model	1136:1155	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	8	33	theme	stable	1652:1657	arg1	structure					1663:1671	a more stable gel structure	1645:1671	a more stable gel structure	1645:1671	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	7	34	theme	0.4	1239:1241	arg1	%					1242:1242	%	1242:1242	%	1242:1242	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	5	35	theme	loss	932:935	arg1	modulus					937:943	loss modulus	932:943		932:162	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	5	35	theme	loss	932:935	arg1	"					-1:-1		946:-1		946:-1	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	5	36	theme	rheological	837:847	arg1	results					849:855	the rheological results	833:855	the rheological results	833:855	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	4	37	theme	significant	676:686	arg1	differences					688:698	no significant differences	673:698	no significant differences	673:698	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	3	38	theme	samples	556:562	arg1	cohesiveness					521:532	cohesiveness	521:532	cohesiveness	521:532	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	3	38	theme	samples	556:562	arg1	chewiness					539:547	chewiness	539:547	chewiness	539:547	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	3	38	theme	samples	556:562	arg1	hardness					511:518	hardness	511:518	hardness	511:518	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	7	39	theme	40	1215:1216	arg1	%					1217:1217	%	1217:1217	%	1217:1217	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	8	40	theme	NaHCO3	1630:1635	arg1	addition					1610:1617	the addition	1606:1617	the addition of KGM and NaHCO3	1606:1635	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	5	41	theme	gel	972:974	arg1	structure					976:984	a firmer gel structure	963:984	a firmer gel structure	963:984	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	7	42	theme	%	1217:1217	arg1	samples					1223:1229	the 40% SPS samples	1211:1229	the 40% SPS samples	1211:1229	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	2	43	theme	isolate	358:364	arg1	mixtures					334:341	mixtures	334:341	mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations	334:446	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	2	44	theme	NaHCO3	386:391	arg1	mixtures					334:341	mixtures	334:341	mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations	334:446	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	1	45	theme	rheological	226:236	arg1	properties					238:247	rheological properties	226:247	rheological properties	226:247	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	7	46	theme	KGM	1244:1246	arg1	samples					1248:1254	the 0.4% KGM samples	1235:1254	the 0.4% KGM samples	1235:1254	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	1	47	theme	konjac	168:173	arg1	KGM					188:190	KGM	188:190	KGM	188:190	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	1	47	theme	konjac	168:173	arg1	glucomannan					175:185	konjac glucomannan	168:185	konjac glucomannan (KGM)	168:191	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	5	48	theme	storage	907:913	arg1	modulus					915:921	the storage modulus	903:921	the storage modulus (G')	903:926	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	5	48	theme	storage	907:913	arg1	G					924:924	G'	924:925	G'	924:925	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	3	49	dep	hardness	511:518	arg1	the					507:509	the	507:509	the	507:509	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	2	50	theme	protein	350:356	arg1	SPI					367:369	SPI	367:369	SPI	367:369	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	2	50	theme	protein	350:356	arg1	isolate					358:364	soy protein isolate	346:364	soy protein isolate (SPI)	346:370	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	0	51	theme	Plant-Based	22:32	arg1	Gel					34:36	Plant-Based Gel	22:36	Plant-Based Gel	22:36	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	5	52	theme	G	946:946	arg1	modulus					937:943	loss modulus	932:943		932:162	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	5	52	theme	G	946:946	arg1	"					-1:-1		946:-1		946:-1	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	4	53	theme	L	725:725	arg1	lightness					714:722	lightness	714:722	lightness (L*) between the samples	714:747	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	4	53	theme	L	725:725	arg1	*					726:726	L*	725:726	L*	725:726	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	1	54	theme	glucomannan	175:185	arg1	effect					128:133	the effect	124:133	the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds	124:294	This study investigated the effect of sweet potato starch (SPS) and konjac glucomannan (KGM) on the textural, color, sensory, rheological properties, and microstructures of plant-based pork rinds.					
35630579	6	55	theme	structure	1125:1133	arg1	formation					1093:1101	the formation	1089:1101	the formation of a more compact gel structure	1089:1133	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	4	56	dep	showed	666:671	arg1	found					705:709	found	705:709	showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations	666:817	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	2	57	theme	oil	377:379	arg1	mixtures					334:341	mixtures	334:341	mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations	334:446	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	5	58	theme	firmer	965:970	arg1	structure					976:984	a firmer gel structure	963:984	a firmer gel structure	963:984	Furthermore, the rheological results showed that adding SPS and KGM increased both the storage modulus (G') and loss modulus (G''), indicating a firmer gel structure.					
35630579	8	59	theme	gel	1659:1661	arg1	structure					1663:1671	a more stable gel structure	1645:1671	a more stable gel structure	1645:1671	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	7	60	theme	comparable	1330:1339	arg1	texture					1341:1347	a comparable texture	1328:1347	a comparable texture	1328:1347	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	4	61	theme	KGM	800:802	arg1	concentrations					804:817	KGM concentrations	800:817	KGM concentrations	800:817	The results obtained via a colorimeter showed no significant differences were found in lightness (L*) between the samples and natural pork rinds after adjusting the SPS and KGM concentrations.					
35630579	3	62	theme	appropriate	593:603	arg1	SPS					605:607	appropriate SPS	593:607	appropriate SPS	593:607	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	7	63	theme	objective	1176:1184	arg1	evaluation					1194:1203	a more objective sensory evaluation	1169:1203	a more objective sensory evaluation	1169:1203	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	8	64	theme	gelling	1432:1438	arg1	mechanism					1440:1448	the gelling mechanism	1428:1448	the gelling mechanism of plant-based pork rinds	1428:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	6	65	theme	gel	1121:1123	arg1	structure					1125:1133	a more compact gel structure	1106:1133	a more compact gel structure	1106:1133	The images obtained via scanning electron microscopy (SEM) showed that the SPS and KGM contributed to the formation of a more compact gel structure.					
35630579	7	66	theme	natural	1293:1299	arg1	pork					1301:1304	natural pork	1293:1304	natural pork	1293:1304	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	0	67	dep	Rinds	11:15	arg1	Rinds					11:15	Pork Rinds	6:15	Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan	6:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	67	dep	Rinds	11:15	arg1	Influence					43:51	The Influence	39:51	The Influence of Sweet Potato Starch	39:74	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	0	67	dep	Rinds	11:15	arg1	Glucomannan					87:97	Glucomannan	87:97	Glucomannan	87:97	Mimic Pork Rinds from Plant-Based Gel: The Influence of Sweet Potato Starch and Konjac Glucomannan.					
35630579	8	68	theme	plant-based	1453:1463	arg1	rinds					1470:1474	plant-based pork rinds	1453:1474	plant-based pork rinds	1453:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	2	69	theme	soy	346:348	arg1	SPI					367:369	SPI	367:369	SPI	367:369	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	2	69	theme	soy	346:348	arg1	isolate					358:364	soy protein isolate	346:364	soy protein isolate (SPI)	346:370	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	7	70	theme	sensory	1186:1192	arg1	evaluation					1194:1203	a more objective sensory evaluation	1169:1203	a more objective sensory evaluation	1169:1203	A mathematical model allowed for a more objective sensory evaluation, with the 40% SPS samples and the 0.4% KGM samples being considered the most similar to natural pork rinds, which provided a comparable texture, appearance, and mouthfeel.					
35630579	8	71	theme	possible	1399:1406	arg1	model					1418:1422	a possible schematic model	1397:1422	a possible schematic model for the gelling mechanism of plant-based pork rinds	1397:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	2	72	theme	different	411:419	arg1	SPS					421:423	different SPS	411:423	different SPS	411:423	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	3	73	theme	KGM	613:615	arg1	addition					617:624	KGM addition	613:624	KGM addition	613:624	The texture profile analysis (TPA) results indicated that the hardness, cohesiveness, and chewiness of the samples improved significantly after appropriate SPS and KGM addition.					
35630579	8	74	theme	samples	1525:1531	arg1	structures					1507:1516	the three-dimensional network structures	1477:1516	the three-dimensional network structures of the samples	1477:1531	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
35630579	2	75	theme	soy	373:375	arg1	oil					377:379	soy oil	373:379	soy oil	373:379	Plant-based gels were prepared using mixtures of soy protein isolate (SPI), soy oil, and NaHCO3 supplemented with different SPS and KGM concentrations.					
35630579	8	76	theme	rinds	1470:1474	arg1	mechanism					1440:1448	the gelling mechanism	1428:1448	the gelling mechanism of plant-based pork rinds	1428:1474	This study proposed a possible schematic model for the gelling mechanism of plant-based pork rinds: the three-dimensional network structures of the samples may result from the interaction between SPS, SPI, and soybean oil, while the addition of KGM and NaHCO3 enabled a more stable gel structure.					
36330860	5	0	theme	cellulose	796:804	arg1	matrix					806:811	the cellulose matrix	792:811	the cellulose matrix	792:811	The results indicated that rectorite microplates were uniformly distributed in the cellulose matrix.					
36330860	7	1	theme	food	1242:1245	arg1	material					1257:1264	a sustainable food packaging material	1228:1264	a sustainable food packaging material	1228:1264	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	4	2	dep	structure	544:552	arg1	The					540:542	The	540:542	The	540:542	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	7	3	theme	water	1132:1136	arg1	vapor					1138:1142	the water vapor and oxygen permeabilities	1128:1168	vapor	1138:1142	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	3	4	theme	composite	523:531	arg1	films					533:537	the composite films	519:537	the composite films	519:537	In this work, rectorite microplates were incorporated into the cellulose matrix by a facile blending method to fabricate the composite films.					
36330860	2	5	theme	UV	350:351	arg1	property					364:371	sufficient ultraviolet (UV) shielding property	326:371	sufficient ultraviolet (UV) shielding property	326:371	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	7	6	theme	potential	1203:1211	arg1	application					1213:1223	a potential application	1201:1223	a potential application as a sustainable food packaging material	1201:1264	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	6	7	with	film	893:896	arg1	RCRF-14					929:935	RCRF-14	929:935	RCRF-14	929:935	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	7	with	film	893:896	arg1	content					920:926	14 wt% rectorite content	903:926	14 wt% rectorite content (RCRF-14)	903:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	7	8	theme	mechanical	1092:1101	arg1	properties					1103:1112	the mechanical properties	1088:1112	the mechanical properties	1088:1112	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	4	9	theme	scanning	640:647	arg1	microscopy					658:667	scanning electron microscopy	640:667	scanning electron microscopy	640:667	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	1	10	theme	biodegradable	173:185	arg1	materials					214:222	biodegradable high-performance packaging materials	173:222	biodegradable high-performance packaging materials	173:222	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	0	11	theme	sustainable	55:65	arg1	packaging					67:75	sustainable packaging	55:75	sustainable packaging	55:75	Fabrication of cellulose/rectorite composite films for sustainable packaging.					
36330860	6	12	theme	shielding	1012:1020	arg1	property					1022:1029	a good UV shielding property	1002:1029	a good UV shielding property	1002:1029	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	1	13	theme	high-performance	187:202	arg1	materials					214:222	biodegradable high-performance packaging materials	173:222	biodegradable high-performance packaging materials	173:222	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	7	14	theme	cellulose	1177:1185	arg1	film					1187:1190	the cellulose film	1173:1190	the cellulose film	1173:1190	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	6	15	theme	rectorite	910:918	arg1	RCRF-14					929:935	RCRF-14	929:935	RCRF-14	929:935	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	15	theme	rectorite	910:918	arg1	content					920:926	14 wt% rectorite content	903:926	14 wt% rectorite content (RCRF-14)	903:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	16	theme	blocking	818:825	arg1	percentages					827:837	The blocking percentages	814:837	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14)	814:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	2	17	theme	ultraviolet	337:347	arg1	property					364:371	sufficient ultraviolet (UV) shielding property	326:371	sufficient ultraviolet (UV) shielding property	326:371	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	1	18	theme	packaging	204:212	arg1	materials					214:222	biodegradable high-performance packaging materials	173:222	biodegradable high-performance packaging materials	173:222	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	7	19	theme	film	1187:1190	arg1	vapor					1138:1142	the water vapor and oxygen permeabilities	1128:1168	vapor	1138:1142	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	7	19	theme	film	1187:1190	arg1	permeabilities					1155:1168	the water vapor and oxygen permeabilities	1128:1168	permeabilities	1155:1168	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	2	20	theme	sufficient	326:335	arg1	property					364:371	sufficient ultraviolet (UV) shielding property	326:371	sufficient ultraviolet (UV) shielding property	326:371	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	1	21	theme	materials	214:222	arg1	development					158:168	the development	154:168	the development of biodegradable high-performance packaging materials	154:222	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	0	22	theme	composite	35:43	arg1	films					45:49	cellulose/rectorite composite films	15:49	cellulose/rectorite composite films	15:49	Fabrication of cellulose/rectorite composite films for sustainable packaging.					
36330860	7	23	theme	rectorite	1059:1067	arg1	addition					1047:1054	the addition	1043:1054	the addition of rectorite	1043:1067	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	1	24	theme	environmental	101:113	arg1	pollution					115:123	the environmental pollution	97:123	the environmental pollution caused by plastic packaging	97:151	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	4	25	theme	electron	649:656	arg1	microscopy					658:667	scanning electron microscopy	640:667	scanning electron microscopy	640:667	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	0	26	theme	cellulose/rectorite	15:33	arg1	films					45:49	cellulose/rectorite composite films	15:49	cellulose/rectorite composite films	15:49	Fabrication of cellulose/rectorite composite films for sustainable packaging.					
36330860	4	27	theme	films	586:590	arg1	properties					558:567	properties	558:567	properties	558:567	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	4	27	theme	films	586:590	arg1	structure					544:552	structure	544:552	structure	544:552	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	4	28	dep	FT-IR	614:618	arg1	etc					708:710	test etc	703:710	test etc	703:710	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	7	29	theme	packaging	1247:1255	arg1	material					1257:1264	a sustainable food packaging material	1228:1264	a sustainable food packaging material	1228:1264	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	3	30	theme	facile	483:488	arg1	method					499:504	a facile blending method	481:504	a facile blending method to fabricate the composite films	481:537	In this work, rectorite microplates were incorporated into the cellulose matrix by a facile blending method to fabricate the composite films.					
36330860	7	31	theme	oxygen	1148:1153	arg1	permeabilities					1155:1168	the water vapor and oxygen permeabilities	1128:1168	permeabilities	1155:1168	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	4	32	theme	composite	576:584	arg1	films					586:590	the composite films	572:590	the composite films	572:590	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	6	33	theme	14 wt	903:907	arg1	RCRF-14					929:935	RCRF-14	929:935	RCRF-14	929:935	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	33	theme	14 wt	903:907	arg1	content					920:926	14 wt% rectorite content	903:926	14 wt% rectorite content (RCRF-14)	903:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	4	34	theme	mechanical	681:690	arg1	properties					692:701	mechanical properties	681:701	mechanical properties	681:701	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	0	35	theme	films	45:49	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of cellulose/rectorite composite films for sustainable packaging.	0:76	Fabrication of cellulose/rectorite composite films for sustainable packaging.					
36330860	5	36	theme	rectorite	740:748	arg1	microplates					750:760	rectorite microplates	740:760	rectorite microplates	740:760	The results indicated that rectorite microplates were uniformly distributed in the cellulose matrix.					
36330860	1	37	theme	research	237:244	arg1	hotspot					246:252	a research hotspot	235:252	a research hotspot	235:252	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	6	38	theme	%	908:908	arg1	RCRF-14					929:935	RCRF-14	929:935	RCRF-14	929:935	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	38	theme	%	908:908	arg1	content					920:926	14 wt% rectorite content	903:926	14 wt% rectorite content (RCRF-14)	903:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	2	39	theme	shielding	354:362	arg1	property					364:371	sufficient ultraviolet (UV) shielding property	326:371	sufficient ultraviolet (UV) shielding property	326:371	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	3	40	theme	rectorite	412:420	arg1	microplates					422:432	rectorite microplates	412:432	rectorite microplates	412:432	In this work, rectorite microplates were incorporated into the cellulose matrix by a facile blending method to fabricate the composite films.					
36330860	6	41	theme	composite	883:891	arg1	film					893:896	the cellulose/rectorite composite film	859:896	the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14)	859:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	6	42	theme	cellulose/rectorite	863:881	arg1	film					893:896	the cellulose/rectorite composite film	859:896	the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14)	859:936	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	2	43	theme	packaging	285:293	arg1	Cellulose					255:263	Cellulose	255:263	Cellulose	255:263	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	2	43	theme	packaging	285:293	arg1	material					295:302	a promising food packaging material	268:302	a promising food packaging material	268:302	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	1	44	theme	plastic	135:141	arg1	packaging					143:151	plastic packaging	135:151	plastic packaging	135:151	In order to reduce the environmental pollution caused by plastic packaging, the development of biodegradable high-performance packaging materials has become a research hotspot.					
36330860	4	45	theme	X-ray	621:625	arg1	diffraction					627:637	X-ray diffraction	621:637	X-ray diffraction	621:637	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	2	46	theme	food	280:283	arg1	Cellulose					255:263	Cellulose	255:263	Cellulose	255:263	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	2	46	theme	food	280:283	arg1	material					295:302	a promising food packaging material	268:302	a promising food packaging material	268:302	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	4	47	theme	test	703:706	arg1	etc					708:710	test etc	703:710	test etc	703:710	The structure and properties of the composite films were characterized by FT-IR, X-ray diffraction, scanning electron microscopy, UV-vis and mechanical properties test etc.					
36330860	3	48	theme	blending	490:497	arg1	method					499:504	a facile blending method	481:504	a facile blending method to fabricate the composite films	481:537	In this work, rectorite microplates were incorporated into the cellulose matrix by a facile blending method to fabricate the composite films.					
36330860	2	49	theme	promising	270:278	arg1	Cellulose					255:263	Cellulose	255:263	Cellulose	255:263	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	2	49	theme	promising	270:278	arg1	material					295:302	a promising food packaging material	268:302	a promising food packaging material	268:302	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	3	50	theme	cellulose	461:469	arg1	matrix					471:476	the cellulose matrix	457:476	the cellulose matrix	457:476	In this work, rectorite microplates were incorporated into the cellulose matrix by a facile blending method to fabricate the composite films.					
36330860	6	51	theme	UV	1009:1010	arg1	property					1022:1029	a good UV shielding property	1002:1029	a good UV shielding property	1002:1029	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
36330860	7	52	theme	sustainable	1230:1240	arg1	material					1257:1264	a sustainable food packaging material	1228:1264	a sustainable food packaging material	1228:1264	Meanwhile, the addition of rectorite obviously improved the mechanical properties and decreased the water vapor and oxygen permeabilities of the cellulose film, showing a potential application as a sustainable food packaging material.					
36330860	2	53	theme	mechanical	377:386	arg1	strength					388:395	mechanical strength	377:395	mechanical strength	377:395	Cellulose is a promising food packaging material, but it usually lacks sufficient ultraviolet (UV) shielding property and mechanical strength.					
36330860	6	54	theme	good	1004:1007	arg1	property					1022:1029	a good UV shielding property	1002:1029	a good UV shielding property	1002:1029	The blocking percentages for UVA and UVB for the cellulose/rectorite composite film with 14 wt% rectorite content (RCRF-14) could reach as high as 97.8 % and 96.0 %, respectively, showing a good UV shielding property.					
34982864	7	0	theme	indirect	908:915	arg1	restorations					933:944	indirect resin composite restorations	908:944	indirect resin composite restorations made from flexible and rigid stone models	908:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	0	1	dep	Analysis	104:111	arg1	Influence					4:12	The Influence	0:12	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations	0:91	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	9	2	theme	flexible	1221:1228	arg1	model					1245:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	0	3	from	Influence	4:12	arg1	Adaptation					50:59	the Marginal Adaptation	37:59	the Marginal Adaptation of Inlay Composite Restorations	37:91	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	5	4	dep	measured	775:782	arg1	ImageJ					795:800	ImageJ	795:800	ImageJ	795:800	Absolute marginal discrepancies were measured digitally (ImageJ).					
34982864	7	5	theme	marginal	884:891	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	2	6	theme	permanent	324:332	arg1	teeth					340:344	permanent molar teeth	324:344	permanent molar teeth	324:344	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	1	7	theme	indirect	215:222	arg1	restorations					240:251	indirect resin composite restorations	215:251	indirect resin composite restorations	215:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	0	8	theme	Restorations	80:91	arg1	Adaptation					50:59	the Marginal Adaptation	37:59	the Marginal Adaptation of Inlay Composite Restorations	37:91	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	2	9	theme	cavity	265:270	arg1	preparations					272:283	Thirty-six cavity preparations	254:283	Thirty-six cavity preparations	254:283	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	1	10	theme	resin	224:228	arg1	restorations					240:251	indirect resin composite restorations	215:251	indirect resin composite restorations	215:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	9	11	theme	composite	1315:1323	arg1	restorations					1325:1336	the indirect resin composite restorations	1296:1336	the indirect resin composite restorations	1296:1336	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	2	12	theme	Thirty-six	254:263	arg1	preparations					272:283	Thirty-six cavity preparations	254:283	Thirty-six cavity preparations	254:283	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	7	13	theme	SD	872:873	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	2	14	theme	molar	334:338	arg1	teeth					340:344	permanent molar teeth	324:344	permanent molar teeth	324:344	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	1	15	theme	composite	230:238	arg1	restorations					240:251	indirect resin composite restorations	215:251	indirect resin composite restorations	215:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	6	16	theme	one-way	836:842	arg1	p⟨					851:852	p⟨ 0.05	851:857	p⟨ 0.05	851:857	The results were compared using one-way ANOVA (p⟨ 0.05).					
34982864	6	16	theme	one-way	836:842	arg1	ANOVA					844:848	one-way ANOVA	836:848	one-way ANOVA (p⟨ 0.05)	836:858	The results were compared using one-way ANOVA (p⟨ 0.05).					
34982864	2	17	from	restorations	308:319	arg1	teeth					340:344	permanent molar teeth	324:344	permanent molar teeth	324:344	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	3	18	theme	material	414:421	arg1	G					570:570	G(MODELPVS)	570:580	G(MODELPVS)	570:580	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	polyvinylsiloxane					605:621	flexible polyvinylsiloxane	596:621	flexible polyvinylsiloxane for models	596:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	alginate					529:536	alginate	529:536	alginate	529:536	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	G					511:511	G(IMPRESSIONPVS)	511:526	G(IMPRESSIONPVS)	511:526	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	polyvinylsiloxane					447:463	polyvinylsiloxane	447:463	polyvinylsiloxane	447:463	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	model					484:488	type IV stone model	470:488	type IV stone model	470:488	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	polyvinylsiloxane					551:567	flexible polyvinylsiloxane	542:567	flexible polyvinylsiloxane	542:567	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	G					437:437	G	437:437	G(STONE)	437:444	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	18	theme	material	414:421	arg1	alginate					583:590	alginate	583:590	alginate	583:590	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	9	19	theme	stone	1239:1243	arg1	model					1245:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	7	20	dep	G	1004:1004	arg1	IMPRESSIONPVS					1033:1045	IMPRESSIONPVS	1033:1045	IMPRESSIONPVS	1033:1045	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	20	dep	G	1004:1004	arg1	G					1031:1031	G(IMPRESSIONPVS)	1031:1046	G(IMPRESSIONPVS)	1031:1046	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	20	dep	G	1004:1004	arg1	203.25					1082:1087	203.25 (±65.93) μm	1082:1099	203.25 (±65.93) μm	1082:1099	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	20	dep	G	1004:1004	arg1	μm					1065:1066	221.50 (±61.73) μm	1049:1066	221.50 (±61.73) μm	1049:1066	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	21	theme	mean	865:868	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	8	22	theme	flexible	1175:1182	arg1	p=0.78					1208:1213	p=0.78	1208:1213	p=0.78	1208:1213	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	8	22	theme	flexible	1175:1182	arg1	models					1200:1205	the flexible and rigid stone models	1171:1205	the flexible and rigid stone models (p=0.78)	1171:1214	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	5	23	theme	marginal	747:754	arg1	discrepancies					756:768	Absolute marginal discrepancies	738:768	Absolute marginal discrepancies	738:768	Absolute marginal discrepancies were measured digitally (ImageJ).					
34982864	7	24	theme	±	870:870	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	8	25	theme	stone	1194:1198	arg1	p=0.78					1208:1213	p=0.78	1208:1213	p=0.78	1208:1213	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	8	25	theme	stone	1194:1198	arg1	models					1200:1205	the flexible and rigid stone models	1171:1205	the flexible and rigid stone models (p=0.78)	1171:1214	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	3	26	theme	flexible	596:603	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	26	theme	flexible	596:603	arg1	polyvinylsiloxane					605:621	flexible polyvinylsiloxane	596:621	flexible polyvinylsiloxane for models	596:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	1	27	theme	restorations	240:251	arg1	adaptation					201:210	the marginal adaptation	188:210	the marginal adaptation of indirect resin composite restorations	188:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	7	28	dep	G	1031:1031	arg1	MODELPVS					1071:1078	MODELPVS	1071:1078	MODELPVS	1071:1078	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	28	dep	G	1031:1031	arg1	G					1069:1069	G	1069:1069	G(MODELPVS)	1069:1079	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	9	29	theme	rigid	1233:1237	arg1	model					1245:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model	1217:1249	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	8	30	theme	rigid	1188:1192	arg1	p=0.78					1208:1213	p=0.78	1208:1213	p=0.78	1208:1213	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	8	30	theme	rigid	1188:1192	arg1	models					1200:1205	the flexible and rigid stone models	1171:1205	the flexible and rigid stone models (p=0.78)	1171:1214	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	3	31	theme	impressions/model	396:412	arg1	G					570:570	G(MODELPVS)	570:580	G(MODELPVS)	570:580	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	polyvinylsiloxane					605:621	flexible polyvinylsiloxane	596:621	flexible polyvinylsiloxane for models	596:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	alginate					529:536	alginate	529:536	alginate	529:536	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	G					511:511	G(IMPRESSIONPVS)	511:526	G(IMPRESSIONPVS)	511:526	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	polyvinylsiloxane					447:463	polyvinylsiloxane	447:463	polyvinylsiloxane	447:463	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	model					484:488	type IV stone model	470:488	type IV stone model	470:488	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	polyvinylsiloxane					551:567	flexible polyvinylsiloxane	542:567	flexible polyvinylsiloxane	542:567	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	G					437:437	G	437:437	G(STONE)	437:444	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	31	theme	impressions/model	396:412	arg1	alginate					583:590	alginate	583:590	alginate	583:590	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	8	32	theme	marginal	1111:1118	arg1	discrepancies					1120:1132	Absolute marginal discrepancies	1102:1132	Absolute marginal discrepancies	1102:1132	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	7	33	theme	absolute	875:882	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	3	34	theme	control	496:502	arg1	group					504:508	a control group	494:508	a control group	494:508	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	7	35	theme	flexible	956:963	arg1	models					981:986	flexible and rigid stone models	956:986	flexible and rigid stone models	956:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	0	36	theme	MicroCT	96:102	arg1	Analysis					104:111	A MicroCT Analysis	94:111	A MicroCT Analysis	94:111	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	1	37	theme	study	130:134	arg1	aim					118:120	The aim	114:120	The aim of this study	114:134	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	9	38	theme	marginal	1273:1280	arg1	adaptation					1282:1291	the marginal adaptation	1269:1291	the marginal adaptation of the indirect resin composite restorations	1269:1336	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	0	39	theme	Model	28:32	arg1	Influence					4:12	The Influence	0:12	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations	0:91	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	1	40	theme	flexible	169:176	arg1	models					178:183	flexible models	169:183	flexible models	169:183	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	0	41	theme	Flexible	19:26	arg1	Model					28:32	a Flexible Model	17:32	a Flexible Model	17:32	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	1	42	theme	models	178:183	arg1	influence					156:164	the influence	152:164	the influence of flexible models on the marginal adaptation of indirect resin composite restorations	152:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	7	43	theme	stone	975:979	arg1	models					981:986	flexible and rigid stone models	956:986	flexible and rigid stone models	956:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	7	44	theme	restorations	933:944	arg1	discrepancy					893:903	The mean ± SD absolute marginal discrepancy	861:903	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models	861:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	8	45	theme	Absolute	1102:1109	arg1	discrepancies					1120:1132	Absolute marginal discrepancies	1102:1132	Absolute marginal discrepancies	1102:1132	Absolute marginal discrepancies were not significantly influenced by the flexible and rigid stone models (p=0.78).					
34982864	5	46	theme	Absolute	738:745	arg1	discrepancies					756:768	Absolute marginal discrepancies	738:768	Absolute marginal discrepancies	738:768	Absolute marginal discrepancies were measured digitally (ImageJ).					
34982864	3	47	dep	combinations	423:434	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	G					570:570	G(MODELPVS)	570:580	G(MODELPVS)	570:580	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	MODELPVS					572:579	MODELPVS	572:579	MODELPVS	572:579	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	polyvinylsiloxane					605:621	flexible polyvinylsiloxane	596:621	flexible polyvinylsiloxane for models	596:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	G					511:511	G(IMPRESSIONPVS)	511:526	G(IMPRESSIONPVS)	511:526	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	polyvinylsiloxane					447:463	polyvinylsiloxane	447:463	polyvinylsiloxane	447:463	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	model					484:488	type IV stone model	470:488	type IV stone model	470:488	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	G					437:437	G	437:437	G(STONE)	437:444	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	alginate					583:590	alginate	583:590	alginate	583:590	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	IMPRESSIONPVS					513:525	IMPRESSIONPVS	513:525	IMPRESSIONPVS	513:525	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	47	dep	combinations	423:434	arg1	STONE					439:443	STONE	439:443	STONE	439:443	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	1	48	from	influence	156:164	arg1	adaptation					201:210	the marginal adaptation	188:210	the marginal adaptation of indirect resin composite restorations	188:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	9	49	theme	indirect	1300:1307	arg1	restorations					1325:1336	the indirect resin composite restorations	1296:1336	the indirect resin composite restorations	1296:1336	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	3	50	theme	type	470:473	arg1	model					484:488	type IV stone model	470:488	type IV stone model	470:488	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	50	theme	type	470:473	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	51	theme	flexible	542:549	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	51	theme	flexible	542:549	arg1	polyvinylsiloxane					551:567	flexible polyvinylsiloxane	542:567	flexible polyvinylsiloxane	542:567	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	2	52	theme	II	305:306	arg1	restorations					308:319	class II restorations	299:319	class II restorations in permanent molar teeth	299:344	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	4	53	theme	respective	677:686	arg1	teeth					688:692	their respective teeth	671:692	their respective teeth	671:692	All restorations were positioned on their respective teeth and evaluated by micro-computed tomography.					
34982864	7	54	theme	rigid	969:973	arg1	models					981:986	flexible and rigid stone models	956:986	flexible and rigid stone models	956:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	4	55	theme	micro-computed	711:724	arg1	tomography					726:735	micro-computed tomography	711:735	micro-computed tomography	711:735	All restorations were positioned on their respective teeth and evaluated by micro-computed tomography.					
34982864	7	56	theme	resin	917:921	arg1	restorations					933:944	indirect resin composite restorations	908:944	indirect resin composite restorations made from flexible and rigid stone models	908:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	2	57	theme	class	299:303	arg1	restorations					308:319	class II restorations	299:319	class II restorations in permanent molar teeth	299:344	Thirty-six cavity preparations were made for class II restorations in permanent molar teeth.					
34982864	9	58	theme	resin	1309:1313	arg1	restorations					1325:1336	the indirect resin composite restorations	1296:1336	the indirect resin composite restorations	1296:1336	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	7	59	theme	composite	923:931	arg1	restorations					933:944	indirect resin composite restorations	908:944	indirect resin composite restorations made from flexible and rigid stone models	908:986	The mean ± SD absolute marginal discrepancy of indirect resin composite restorations made from flexible and rigid stone models was as follows: G(STONE), 206 (±79.95) μm; G(IMPRESSIONPVS), 221.50 (±61.73) μm; G(MODELPVS), 203.25 (±65.93) μm.					
34982864	9	60	theme	restorations	1325:1336	arg1	adaptation					1282:1291	the marginal adaptation	1269:1291	the marginal adaptation of the indirect resin composite restorations	1269:1336	The flexible or rigid stone model did not influence the marginal adaptation of the indirect resin composite restorations.					
34982864	1	61	theme	marginal	192:199	arg1	adaptation					201:210	the marginal adaptation	188:210	the marginal adaptation of indirect resin composite restorations	188:251	The aim of this study was to evaluate the influence of flexible models on the marginal adaptation of indirect resin composite restorations.					
34982864	0	62	theme	Marginal	41:48	arg1	Adaptation					50:59	the Marginal Adaptation	37:59	the Marginal Adaptation of Inlay Composite Restorations	37:91	The Influence of a Flexible Model on the Marginal Adaptation of Inlay Composite Restorations: A MicroCT Analysis.					
34982864	3	63	theme	stone	478:482	arg1	model					484:488	type IV stone model	470:488	type IV stone model	470:488	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
34982864	3	63	theme	stone	478:482	arg1	combinations					423:434	three impressions/model material combinations	390:434	three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models	390:632	Three groups (n=12) were defined following three impressions/model material combinations: G(STONE), polyvinylsiloxane, and type IV stone model, as a control group; G(IMPRESSIONPVS), alginate and flexible polyvinylsiloxane; G(MODELPVS), alginate and flexible polyvinylsiloxane for models.					
35853409	12	0	from	occurrence	1501:1510	arg1	matrixes					1536:1543	environmental matrixes	1522:1543	environmental matrixes from Hangzhou Bay	1522:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	0	from	occurrence	1501:1510	arg1	Bay					1559:1561	Bay	1559:1561	Bay	1559:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	1	theme	behaviors	1627:1635	arg1	understanding					1596:1608	the better understanding	1585:1608	the better understanding of environmental behaviors of MPs in estuarine sea environment	1585:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	7	2	theme	Average	799:805	arg1	abundance					807:815	Average abundance	799:815	Average abundance of MPs in marine organisms (n = 388)	799:852	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	12	3	from	environment	1661:1671	arg1	behaviors					1627:1635	environmental behaviors	1613:1635	environmental behaviors of MPs in estuarine sea environment	1613:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	5	4	from	shape	602:606	arg1	seawater					618:625	seawater	618:625	seawater	618:625	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	5	4	from	shape	602:606	arg1	sediment					631:638	sediment	631:638	sediment	631:638	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	11	5	from	compositions	1369:1380	arg1	zooplankton					1401:1411	zooplankton	1401:1411	zooplankton	1401:1411	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	5	from	compositions	1369:1380	arg1	fish					1392:1395	fish	1392:1395	fish	1392:1395	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	4	6	theme	MPs	433:435	arg1	Size					425:428	Size	425:428	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm)	425:480	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	6	7	theme	MPs	674:676	arg1	polyethylene					682:693	polyethylene	682:693	polyethylene	682:693	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	7	theme	MPs	674:676	arg1	composition					659:669	The major polymer composition	641:669	The major polymer composition of MPs	641:676	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	7	theme	MPs	674:676	arg1	PE					696:697	PE	696:697	PE	696:697	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	12	8	theme	better	1589:1594	arg1	understanding					1596:1608	the better understanding	1585:1608	the better understanding of environmental behaviors of MPs in estuarine sea environment	1585:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	5	9	theme	MPs	611:613	arg1	shape					602:606	the predominant shape	586:606	the predominant shape of MPs in seawater and sediment	586:638	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	5	9	theme	MPs	611:613	arg1	Fiber					563:567	Fiber	563:567	Fiber	563:567	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	1	10	attach	present	101:107	arg1	oceans					119:124	global oceans	112:124	global oceans	112:124	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	1	10	attach	present	101:107	arg2	MPs					85:87	MPs	85:87	MPs	85:87	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	1	10	attach	present	101:107	arg2	Microplastics					70:82	Microplastics	70:82	Microplastics (MPs)	70:88	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	4	11	from	Size	425:428	arg1	sediment					440:447	sediment	440:447	sediment (mean 2.5 mm, range 0.21-5.3 mm)	440:480	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	11	12	theme	mean	1310:1313	arg1	%					1318:1318	mean 44 %	1310:1318	mean 44 %	1310:1318	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	12	theme	mean	1310:1313	arg1	PE					1306:1307	PE	1306:1307	PE (mean 44 %)	1306:1319	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	10	13	theme	textile	1278:1284	arg1	cellulose					1286:1294	textile cellulose	1278:1294	textile cellulose	1278:1294	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	2	14	theme	seawater	234:241	arg1	samples					267:273	seawater, sediment, and organism samples	234:273	seawater, sediment, and organism samples collected from Hangzhou Bay	234:301	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	9	15	theme	total	1178:1182	arg1	MPs					1184:1186	total MPs	1178:1186	total MPs	1178:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	12	16	theme	estuarine	1647:1655	arg1	environment					1661:1671	estuarine sea environment	1647:1671	estuarine sea environment	1647:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	9	17	theme	MPs	1093:1095	arg1	shape					1084:1088	the predominant shape	1068:1088	the predominant shape of MPs	1068:1095	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	17	theme	MPs	1093:1095	arg1	Fiber					1051:1055	Fiber	1051:1055	Fiber	1051:1055	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	12	18	theme	environmental	1522:1534	arg1	matrixes					1536:1543	environmental matrixes	1522:1543	environmental matrixes from Hangzhou Bay	1522:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	1	19	from	oceans	119:124	arg1	present					101:107	present	101:107	present	101:107	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	8	20	theme	trophic	1036:1042	arg1	level					1044:1048	their trophic level	1030:1048	their trophic level	1030:1048	MP abundance in marine organisms was not significantly correlated with their trophic level.					
35853409	6	21	from	polyethylene	682:693	arg1	seawater					714:721	seawater	714:721	seawater	714:721	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	11	22	dep	compositions	1369:1380	arg1	Whereas					1297:1303	Whereas	1297:1303	Whereas	1297:1303	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	6	23	theme	textile	728:734	arg1	cellulose					736:744	textile cellulose	728:744	textile cellulose (60 %)	728:751	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	23	theme	textile	728:734	arg1	%					750:750	60 %	747:750	60 %	747:750	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	23	theme	textile	728:734	arg1	type					774:777	the main polymer type	757:777	the main polymer type of MPs	757:784	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	10	24	theme	mean	1208:1211	arg1	%					1216:1216	mean 58 %	1208:1216	mean 58 %	1208:1216	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	24	theme	mean	1208:1211	arg1	crustacean					1196:1205	crustacean	1196:1205	crustacean (mean 58 %)	1196:1217	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	1	25	from	present	101:107	arg1	oceans					119:124	global oceans	112:124	global oceans	112:124	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	2	26	theme	MPs	227:229	arg1	characteristics					208:222	characteristics	208:222	characteristics	208:222	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	2	26	theme	MPs	227:229	arg1	abundance					194:202	abundance	194:202	abundance	194:202	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	2	27	dep	abundance	194:202	arg1	the					190:192	the	190:192	the	190:192	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	7	28	theme	0.19-1.4 mm	946:956	arg1	size					938:941	the mean size	929:941	the mean size of 0.19-1.4 mm	929:956	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	8	29	theme	MP	959:960	arg1	abundance					962:970	MP abundance	959:970	MP abundance in marine organisms	959:990	MP abundance in marine organisms was not significantly correlated with their trophic level.					
35853409	9	30	theme	marine	1110:1115	arg1	organisms					1117:1125	different marine organisms	1100:1125	different marine organisms	1100:1125	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	2	31	theme	organism	258:265	arg1	samples					267:273	seawater, sediment, and organism samples	234:273	seawater, sediment, and organism samples collected from Hangzhou Bay	234:301	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	7	32	from	abundance	807:815	arg1	n = 388					845:851	n = 388	845:851	n = 388	845:851	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	7	32	from	abundance	807:815	arg1	organisms					834:842	marine organisms	827:842	marine organisms (n = 388)	827:852	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	4	33	dep	sediment	440:447	arg1	mean					450:453	mean 2.5 mm	450:460	mean 2.5 mm	450:460	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	4	33	dep	sediment	440:447	arg1	range					463:467	range 0.21-5.3 mm	463:479	range 0.21-5.3 mm	463:479	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	6	34	dep	mean	700:703	arg1	%					708:708	47 %	705:708	mean 47 %	700:708	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	11	35	theme	polymer	1361:1367	arg1	PE					1306:1307	PE	1306:1307	PE (mean 44 %)	1306:1319	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	35	theme	polymer	1361:1367	arg1	polypropylene					1325:1337	polypropylene	1325:1337	polypropylene (43 %)	1325:1344	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	35	theme	polymer	1361:1367	arg1	compositions					1369:1380	the major polymer compositions	1351:1380	the major polymer compositions of MPs in fish and zooplankton	1351:1411	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	6	36	dep	polyethylene	682:693	arg1	polyethylene					682:693	polyethylene	682:693	polyethylene	682:693	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	36	dep	polyethylene	682:693	arg1	composition					659:669	The major polymer composition	641:669	The major polymer composition of MPs	641:676	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	36	dep	polyethylene	682:693	arg1	PE					696:697	PE	696:697	PE	696:697	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	12	37	theme	MPs	1640:1642	arg1	behaviors					1627:1635	environmental behaviors	1613:1635	environmental behaviors of MPs in estuarine sea environment	1613:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	3	38	theme	MPs	317:319	arg1	Abundance					304:312	Abundance	304:312	Abundance of MPs in seawater (n = 26) and sediment (n = 26)	304:362	Abundance of MPs in seawater (n = 26) and sediment (n = 26) were 0.77-9.6 items/m3 and 44-208 items/kg dw, respectively.					
35853409	6	39	theme	polymer	651:657	arg1	polyethylene					682:693	polyethylene	682:693	polyethylene	682:693	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	39	theme	polymer	651:657	arg1	composition					659:669	The major polymer composition	641:669	The major polymer composition of MPs	641:676	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	39	theme	polymer	651:657	arg1	PE					696:697	PE	696:697	PE	696:697	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	2	40	from	abundance	194:202	arg1	samples					267:273	seawater, sediment, and organism samples	234:273	seawater, sediment, and organism samples collected from Hangzhou Bay	234:301	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	6	41	from	seawater	714:721	arg1	polyethylene					682:693	polyethylene	682:693	polyethylene	682:693	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	41	from	seawater	714:721	arg1	composition					659:669	The major polymer composition	641:669	The major polymer composition of MPs	641:676	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	41	from	seawater	714:721	arg1	PE					696:697	PE	696:697	PE	696:697	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	42	theme	MPs	782:784	arg1	cellulose					736:744	textile cellulose	728:744	textile cellulose (60 %)	728:751	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	42	theme	MPs	782:784	arg1	type					774:777	the main polymer type	757:777	the main polymer type of MPs	757:784	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	5	43	theme	predominant	590:600	arg1	shape					602:606	the predominant shape	586:606	the predominant shape of MPs in seawater and sediment	586:638	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	5	43	theme	predominant	590:600	arg1	Fiber					563:567	Fiber	563:567	Fiber	563:567	Fiber was consistently the predominant shape of MPs in seawater and sediment.					
35853409	12	44	from	behaviors	1627:1635	arg1	environment					1661:1671	estuarine sea environment	1647:1671	estuarine sea environment	1647:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	2	45	theme	sediment	244:251	arg1	samples					267:273	seawater, sediment, and organism samples	234:273	seawater, sediment, and organism samples collected from Hangzhou Bay	234:301	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	6	46	dep	PE	696:697	arg1	mean					700:703	mean	700:703	mean 47 %	700:708	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	1	47	theme	marine	152:157	arg1	organisms					159:167	marine organisms	152:167	marine organisms	152:167	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	10	48	from	MPs	1189:1191	arg1	%					1234:1234	64 %	1231:1234	64 %	1231:1234	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	48	from	MPs	1189:1191	arg1	%					1257:1257	29 %	1254:1257	29 %	1254:1257	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	48	from	MPs	1189:1191	arg1	%					1216:1216	mean 58 %	1208:1216	mean 58 %	1208:1216	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	48	from	MPs	1189:1191	arg1	shellfish					1220:1228	shellfish	1220:1228	shellfish (64 %)	1220:1235	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	48	from	MPs	1189:1191	arg1	crustacean					1196:1205	crustacean	1196:1205	crustacean (mean 58 %)	1196:1217	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	10	48	from	MPs	1189:1191	arg1	cephalopod					1242:1251	cephalopod	1242:1251	cephalopod (29 %)	1242:1258	MPs in crustacean (mean 58 %), shellfish (64 %), and cephalopod (29 %) were dominated by textile cellulose.					
35853409	12	49	theme	MPs	1515:1517	arg1	occurrence					1501:1510	the occurrence	1497:1510	the occurrence of MPs in environmental matrixes from Hangzhou Bay	1497:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	0	50	from	Bay	65:67	arg1	Seawater					17:24	Seawater	17:24	Seawater	17:24	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	50	from	Bay	65:67	arg1	Microplastics					0:12	Microplastics	0:12	Microplastics	0:12	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	50	from	Bay	65:67	arg1	Sediment					27:34	Sediment	27:34	Sediment	27:34	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	50	from	Bay	65:67	arg1	Organisms					41:49	Organisms	41:49	Organisms from Hangzhou Bay	41:67	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	2	51	from	characteristics	208:222	arg1	samples					267:273	seawater, sediment, and organism samples	234:273	seawater, sediment, and organism samples collected from Hangzhou Bay	234:301	This study examined the abundance and characteristics of MPs in seawater, sediment, and organism samples collected from Hangzhou Bay.					
35853409	7	52	theme	mean	933:936	arg1	size					938:941	the mean size	929:941	the mean size of 0.19-1.4 mm	929:956	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	9	53	theme	mean	1141:1144	arg1	%					1159:1159	mean 67 (fish)-93 %	1141:1159	mean 67 (fish)-93 % (zooplankton) of total MPs	1141:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	53	theme	mean	1141:1144	arg1	MPs					1184:1186	total MPs	1178:1186	total MPs	1178:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	53	theme	mean	1141:1144	arg1	zooplankton					1162:1172	zooplankton	1162:1172	zooplankton	1162:1172	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	7	54	theme	0.064	866:870	arg1	items/ind					913:921	0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind	866:921	0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind	866:921	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	3	55	from	Abundance	304:312	arg1	seawater					324:331	seawater (n = 26)	324:340	seawater (n = 26)	324:340	Abundance of MPs in seawater (n = 26) and sediment (n = 26) were 0.77-9.6 items/m3 and 44-208 items/kg dw, respectively.					
35853409	3	55	from	Abundance	304:312	arg1	sediment					346:353	sediment (n = 26)	346:362	sediment (n = 26)	346:362	Abundance of MPs in seawater (n = 26) and sediment (n = 26) were 0.77-9.6 items/m3 and 44-208 items/kg dw, respectively.					
35853409	8	56	theme	marine	975:980	arg1	organisms					982:990	marine organisms	975:990	marine organisms	975:990	MP abundance in marine organisms was not significantly correlated with their trophic level.					
35853409	6	57	theme	major	645:649	arg1	polyethylene					682:693	polyethylene	682:693	polyethylene	682:693	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	57	theme	major	645:649	arg1	composition					659:669	The major polymer composition	641:669	The major polymer composition of MPs	641:676	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	57	theme	major	645:649	arg1	PE					696:697	PE	696:697	PE	696:697	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	9	58	from	shape	1084:1088	arg1	organisms					1117:1125	different marine organisms	1100:1125	different marine organisms	1100:1125	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	6	59	theme	polymer	766:772	arg1	cellulose					736:744	textile cellulose	728:744	textile cellulose (60 %)	728:751	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	59	theme	polymer	766:772	arg1	type					774:777	the main polymer type	757:777	the main polymer type of MPs	757:784	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	12	60	theme	comprehensive	1463:1475	arg1	study					1477:1481	the most comprehensive study	1454:1481	the most comprehensive study	1454:1481	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	60	theme	comprehensive	1463:1475	arg1	this					1446:1449	this	1446:1449	this	1446:1449	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	61	theme	sea	1657:1659	arg1	environment					1661:1671	estuarine sea environment	1647:1671	estuarine sea environment	1647:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	9	62	theme	MPs	1184:1186	arg1	%					1159:1159	mean 67 (fish)-93 %	1141:1159	mean 67 (fish)-93 % (zooplankton) of total MPs	1141:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	62	theme	MPs	1184:1186	arg1	MPs					1184:1186	total MPs	1178:1186	total MPs	1178:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	62	theme	MPs	1184:1186	arg1	zooplankton					1162:1172	zooplankton	1162:1172	zooplankton	1162:1172	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	1	63	located	present	101:107	arg1	oceans					119:124	global oceans	112:124	global oceans	112:124	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	1	63	located	present	101:107	arg2	MPs					85:87	MPs	85:87	MPs	85:87	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	1	63	located	present	101:107	arg2	Microplastics					70:82	Microplastics	70:82	Microplastics (MPs)	70:88	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	6	64	theme	main	761:764	arg1	cellulose					736:744	textile cellulose	728:744	textile cellulose (60 %)	728:751	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	6	64	theme	main	761:764	arg1	type					774:777	the main polymer type	757:777	the main polymer type of MPs	757:784	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	8	65	from	abundance	962:970	arg1	organisms					982:990	marine organisms	975:990	marine organisms	975:990	MP abundance in marine organisms was not significantly correlated with their trophic level.					
35853409	7	66	theme	MPs	820:822	arg1	abundance					807:815	Average abundance	799:815	Average abundance of MPs in marine organisms (n = 388)	799:852	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	7	67	theme	Harpodon	894:901	arg1	nehereus					903:910	Harpodon nehereus	894:910	Harpodon nehereus	894:910	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	7	67	theme	Harpodon	894:901	arg1	0.064					866:870	0.064	866:870	0.064	866:870	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	9	68	theme	fish	1150:1153	arg1	%					1159:1159	mean 67 (fish)-93 %	1141:1159	mean 67 (fish)-93 % (zooplankton) of total MPs	1141:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	68	theme	fish	1150:1153	arg1	MPs					1184:1186	total MPs	1178:1186	total MPs	1178:1186	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	68	theme	fish	1150:1153	arg1	zooplankton					1162:1172	zooplankton	1162:1172	zooplankton	1162:1172	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	6	69	from	type	774:777	arg1	sediment					789:796	sediment	789:796	sediment	789:796	The major polymer composition of MPs was polyethylene (PE; mean 47 %) in seawater, but textile cellulose (60 %) was the main polymer type of MPs in sediment.					
35853409	4	70	dep	larger	511:516	arg1	1.1 mm					541:546	1.1 mm	541:546	1.1 mm	541:546	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	4	70	dep	larger	511:516	arg1	p < 0.05					501:508	p < 0.05	501:508	p < 0.05	501:508	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	12	71	theme	environmental	1613:1625	arg1	behaviors					1627:1635	environmental behaviors	1613:1635	environmental behaviors of MPs in estuarine sea environment	1613:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	7	72	theme	marine	827:832	arg1	n = 388					845:851	n = 388	845:851	n = 388	845:851	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	7	72	theme	marine	827:832	arg1	organisms					834:842	marine organisms	827:842	marine organisms (n = 388)	827:852	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	11	73	theme	major	1355:1359	arg1	PE					1306:1307	PE	1306:1307	PE (mean 44 %)	1306:1319	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	73	theme	major	1355:1359	arg1	polypropylene					1325:1337	polypropylene	1325:1337	polypropylene (43 %)	1325:1344	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	73	theme	major	1355:1359	arg1	compositions					1369:1380	the major polymer compositions	1351:1380	the major polymer compositions of MPs in fish and zooplankton	1351:1411	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	1	74	theme	global	112:117	arg1	oceans					119:124	global oceans	112:124	global oceans	112:124	Microplastics (MPs) are widely present in global oceans, and can pose a threat to marine organisms.					
35853409	12	75	from	MPs	1640:1642	arg1	environment					1661:1671	estuarine sea environment	1647:1671	estuarine sea environment	1647:1671	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	76	from	Bay	1559:1561	arg1	matrixes					1536:1543	environmental matrixes	1522:1543	environmental matrixes from Hangzhou Bay	1522:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	12	76	from	Bay	1559:1561	arg1	occurrence					1501:1510	the occurrence	1497:1510	the occurrence of MPs in environmental matrixes from Hangzhou Bay	1497:1561	To our knowledge, this is the most comprehensive study investigating the occurrence of MPs in environmental matrixes from Hangzhou Bay, which contributes to the better understanding of environmental behaviors of MPs in estuarine sea environment.					
35853409	7	77	dep	0.064	866:870	arg1	2.9					889:891	2.9	889:891	2.9	889:891	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	7	77	dep	0.064	866:870	arg1	to					886:887	to	886:887	to	886:887	Average abundance of MPs in marine organisms (n = 388) ranged from 0.064 (zooplankton) to 2.9 (Harpodon nehereus) items/ind, with the mean size of 0.19-1.4 mm.					
35853409	9	78	theme	predominant	1072:1082	arg1	shape					1084:1088	the predominant shape	1068:1088	the predominant shape of MPs	1068:1095	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	9	78	theme	predominant	1072:1082	arg1	Fiber					1051:1055	Fiber	1051:1055	Fiber	1051:1055	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	4	79	dep	1.1 mm	541:546	arg1	0.13-4.9 mm					549:559	0.13-4.9 mm	549:559	0.13-4.9 mm	549:559	Size of MPs in sediment (mean 2.5 mm, range 0.21-5.3 mm) was significantly (p < 0.05) larger than that in seawater (1.1 mm, 0.13-4.9 mm).					
35853409	0	80	from	Microplastics	0:12	arg1	Seawater					17:24	Seawater	17:24	Seawater	17:24	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	80	from	Microplastics	0:12	arg1	Bay					65:67	Bay	65:67	Bay	65:67	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	80	from	Microplastics	0:12	arg1	Sediment					27:34	Sediment	27:34	Sediment	27:34	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	0	80	from	Microplastics	0:12	arg1	Organisms					41:49	Organisms	41:49	Organisms from Hangzhou Bay	41:67	Microplastics in Seawater, Sediment, and Organisms from Hangzhou Bay.					
35853409	9	81	theme	different	1100:1108	arg1	organisms					1117:1125	different marine organisms	1100:1125	different marine organisms	1100:1125	Fiber was always the predominant shape of MPs in different marine organisms, contributing mean 67 (fish)-93 % (zooplankton) of total MPs.					
35853409	11	82	theme	MPs	1385:1387	arg1	PE					1306:1307	PE	1306:1307	PE (mean 44 %)	1306:1319	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	82	theme	MPs	1385:1387	arg1	polypropylene					1325:1337	polypropylene	1325:1337	polypropylene (43 %)	1325:1344	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
35853409	11	82	theme	MPs	1385:1387	arg1	compositions					1369:1380	the major polymer compositions	1351:1380	the major polymer compositions of MPs in fish and zooplankton	1351:1411	Whereas, PE (mean 44 %) and polypropylene (43 %) were the major polymer compositions of MPs in fish and zooplankton, respectively.					
36834862	6	0	theme	ECM	1077:1079	arg1	components					1081:1090	ECM components	1077:1090	ECM components	1077:1090	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	0	theme	ECM	1077:1079	arg1	protein					1133:1139	the cartilage oligomeric matrix protein	1101:1139	the cartilage oligomeric matrix protein (COMP)	1101:1146	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	0	theme	ECM	1077:1079	arg1	GAGs					1152:1155	GAGs	1152:1155	GAGs	1152:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	2	1	theme	sulfated	304:311	arg1	glycosaminoglycans					313:330	the highly sulfated glycosaminoglycans	293:330	the highly sulfated glycosaminoglycans (GAGs)	293:337	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	1	theme	sulfated	304:311	arg1	GAGs					333:336	GAGs	333:336	GAGs	333:336	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	3	2	theme	cartilage	663:671	arg1	studies					686:692	OA cartilage regeneration studies	660:692	OA cartilage regeneration studies	660:692	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	3	theme	chondrogenic	464:475	arg1	differentiation					477:491	the chondrogenic differentiation	460:491	the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	460:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	5	4	theme	chondrogenic	840:851	arg1	differentiation					853:867	the chondrogenic differentiation	836:867	the chondrogenic differentiation of BM-MSCs	836:878	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	9	5	theme	further	1653:1659	arg1	perspectives					1661:1672	further perspectives	1653:1672	further perspectives of therapeutic application in vivo	1653:1707	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	3	6	theme	stem	520:523	arg1	BM-MCSs					532:538	BM-MCSs	532:538	BM-MCSs	532:538	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	6	theme	stem	520:523	arg1	cells					525:529	bone marrow mesenchymal stem cells	496:529	bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	496:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	1	7	theme	extracellular	176:188	arg1	ECM					198:200	ECM	198:200	ECM	198:200	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	1	7	theme	extracellular	176:188	arg1	matrix					190:195	extracellular matrix	176:195	extracellular matrix (ECM) integrity	176:211	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	6	8	theme	stronger	960:967	arg1	load					980:983	the stronger mechanical load	956:983	the stronger mechanical load	956:983	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	9	theme	not-compressed	1174:1187	arg1	explants					1189:1196	the not-compressed explants	1170:1196	the not-compressed explants	1170:1196	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	7	10	theme	cartilage	1348:1356	arg1	explants					1358:1365	the cartilage explants	1344:1365	the cartilage explants	1344:1365	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	3	11	theme	marrow	501:506	arg1	BM-MCSs					532:538	BM-MCSs	532:538	BM-MCSs	532:538	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	11	theme	marrow	501:506	arg1	cells					525:529	bone marrow mesenchymal stem cells	496:529	bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	496:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	5	12	theme	mechanical	809:818	arg1	load					820:823	The applied mild mechanical load	792:823	The applied mild mechanical load	792:823	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	1	13	theme	mechanical	119:128	arg1	load					130:133	mechanical load	119:133	mechanical load	119:133	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	9	14	theme	application	1689:1699	arg1	perspectives					1661:1672	further perspectives	1653:1672	further perspectives of therapeutic application in vivo	1653:1707	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	6	15	theme	matrix	1126:1131	arg1	protein					1133:1139	the cartilage oligomeric matrix protein	1101:1139	the cartilage oligomeric matrix protein (COMP)	1101:1146	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	15	theme	matrix	1126:1131	arg1	COMP					1142:1145	COMP	1142:1145	COMP	1142:1145	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	5	16	theme	immunohistochemical	904:922	arg1	staining					936:943	immunohistochemical collagen II staining	904:943	immunohistochemical collagen II staining	904:943	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	5	16	theme	immunohistochemical	904:922	arg1	hydrogel					894:901	CS-Tyr/Gel hydrogel	883:901	CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining)	883:944	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	8	17	theme	OA	1435:1436	arg1	explants					1448:1455	the OA cartilage explants	1431:1455	the OA cartilage explants	1431:1455	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	5	18	theme	II	933:934	arg1	staining					936:943	immunohistochemical collagen II staining	904:943	immunohistochemical collagen II staining	904:943	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	5	18	theme	II	933:934	arg1	hydrogel					894:901	CS-Tyr/Gel hydrogel	883:901	CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining)	883:944	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	4	19	from	biointegration	754:767	arg1	explants					782:789	cartilage explants	772:789	cartilage explants	772:789	The CS-Tyr/Gel/BM-MSCs composite showed excellent biointegration on cartilage explants.					
36834862	7	20	from	application	1212:1222	arg1	top					1267:1269	the top	1263:1269	the top of the OA cartilage explants	1263:1298	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	4	21	theme	CS-Tyr/Gel/BM-MSCs	708:725	arg1	composite					727:735	The CS-Tyr/Gel/BM-MSCs composite	704:735	The CS-Tyr/Gel/BM-MSCs composite	704:735	The CS-Tyr/Gel/BM-MSCs composite showed excellent biointegration on cartilage explants.					
36834862	8	22	theme	external	1486:1493	arg1	stimuli					1506:1512	external mechanical stimuli	1486:1512	external mechanical stimuli	1486:1512	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	2	23	theme	primary	345:351	arg1	component					353:361	a primary component	343:361	a primary component of cartilage tissue ECM	343:385	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	1	24	theme	cartilage	93:101	arg1	degradation					78:88	The degradation	74:88	The degradation	74:88	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	6	25	theme	higher	1059:1064	arg1	release					1066:1072	the higher release	1055:1072	the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1055:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	8	26	theme	stimuli	1506:1512	arg1	effects					1475:1481	the damaging effects	1462:1481	the damaging effects of external mechanical stimuli	1462:1512	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	0	27	theme	Chondroitin	0:10	arg1	Hydrogels					35:43	Chondroitin Sulfate-Tyramine-Based Hydrogels	0:43	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.	0:72	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.					
36834862	1	28	theme	due	104:106	arg1	degradation					78:88	The degradation	74:88	The degradation	74:88	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	7	29	theme	cartilage	1281:1289	arg1	explants					1291:1298	the OA cartilage explants	1274:1298	the OA cartilage explants	1274:1298	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	2	30	theme	tissue	376:381	arg1	ECM					383:385	cartilage tissue ECM	366:385	cartilage tissue ECM	366:385	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	5	31	theme	applied	796:802	arg1	load					820:823	The applied mild mechanical load	792:823	The applied mild mechanical load	792:823	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	0	32	theme	Cartilage	49:57	arg1	Repair					66:71	Cartilage Tissue Repair	49:71	Cartilage Tissue Repair	49:71	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.					
36834862	9	33	theme	OA	1562:1563	arg1	investigation					1545:1557	investigation	1545:1557	investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo	1545:1707	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	6	34	theme	OA	1020:1021	arg1	explants					1033:1040	the human OA cartilage explants	1010:1040	the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1010:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	9	35	theme	regenerative	1575:1586	arg1	potential					1588:1596	regenerative potential	1575:1596	regenerative potential	1575:1596	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	1	36	theme	integrity	203:211	arg1	loss					168:171	abundant loss	159:171	abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA)	159:250	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	7	37	theme	CS-Tyr/Gel/BM-MSCs	1231:1248	arg1	composite					1250:1258	the CS-Tyr/Gel/BM-MSCs composite	1227:1258	the CS-Tyr/Gel/BM-MSCs composite	1227:1258	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	8	38	theme	CS-Tyr/Gel/BM-MSCs	1390:1407	arg1	composite					1409:1417	the CS-Tyr/Gel/BM-MSCs composite	1386:1417	the CS-Tyr/Gel/BM-MSCs composite	1386:1417	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	3	39	theme	load	452:455	arg1	effect					431:436	the effect	427:436	the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	427:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	1	40	theme	development	217:227	arg1	loss					168:171	abundant loss	159:171	abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA)	159:250	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	6	41	theme	components	1081:1090	arg1	release					1066:1072	the higher release	1055:1072	the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1055:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	3	42	theme	composite	646:654	arg1	suitability					626:636	the suitability	622:636	the suitability of this composite for OA cartilage regeneration studies	622:692	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	2	43	theme	glycosaminoglycans	313:330	arg1	sulfate					265:271	Chondroitin sulfate	253:271	Chondroitin sulfate (CS)	253:276	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	43	theme	glycosaminoglycans	313:330	arg1	member					283:288	a member	281:288	a member of the highly sulfated glycosaminoglycans (GAGs)	281:337	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	43	theme	glycosaminoglycans	313:330	arg1	component					353:361	a primary component	343:361	a primary component of cartilage tissue ECM	343:385	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	1	44	theme	osteoarthritis	232:245	arg1	development					217:227	development	217:227	development of osteoarthritis (OA)	217:250	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	1	44	theme	osteoarthritis	232:245	arg1	integrity					203:211	extracellular matrix (ECM) integrity	176:211	extracellular matrix (ECM) integrity	176:211	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	9	45	theme	mechanical	1623:1632	arg1	load					1634:1637	the mechanical load	1619:1637	the mechanical load	1619:1637	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	9	46	used	used	1536:1539	arg2	it					1526:1527	it	1526:1527	it	1526:1527	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	3	47	theme	regeneration	673:684	arg1	studies					686:692	OA cartilage regeneration studies	660:692	OA cartilage regeneration studies	660:692	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	2	48	theme	Chondroitin	253:263	arg1	sulfate					265:271	Chondroitin sulfate	253:271	Chondroitin sulfate (CS)	253:276	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	48	theme	Chondroitin	253:263	arg1	member					283:288	a member	281:288	a member of the highly sulfated glycosaminoglycans (GAGs)	281:337	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	48	theme	Chondroitin	253:263	arg1	CS					274:275	CS	274:275	CS	274:275	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	1	49	theme	abundant	159:166	arg1	loss					168:171	abundant loss	159:171	abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA)	159:250	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	3	50	theme	OA	660:661	arg1	studies					686:692	OA cartilage regeneration studies	660:692	OA cartilage regeneration studies	660:692	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	51	theme	mesenchymal	508:518	arg1	BM-MCSs					532:538	BM-MCSs	532:538	BM-MCSs	532:538	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	51	theme	mesenchymal	508:518	arg1	cells					525:529	bone marrow mesenchymal stem cells	496:529	bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	496:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	6	52	theme	mechanical	969:978	arg1	load					980:983	the stronger mechanical load	956:983	the stronger mechanical load	956:983	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	9	53	dep	OA	1562:1563	arg1	cartilage					1565:1573	cartilage	1565:1573	cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo	1565:1707	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	3	54	from	effect	431:436	arg1	differentiation					477:491	the chondrogenic differentiation	460:491	the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	460:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	3	55	theme	bone	496:499	arg1	marrow					501:506	bone marrow	496:506	bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	496:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	5	56	theme	mild	804:807	arg1	load					820:823	The applied mild mechanical load	792:823	The applied mild mechanical load	792:823	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	9	57	theme	therapeutic	1677:1687	arg1	application					1689:1699	therapeutic application	1677:1699	therapeutic application in vivo	1677:1707	Therefore, it can be used for investigation of OA cartilage regenerative potential and mechanisms under the mechanical load in vitro with further perspectives of therapeutic application in vivo.					
36834862	6	58	theme	oligomeric	1115:1124	arg1	protein					1133:1139	the cartilage oligomeric matrix protein	1101:1139	the cartilage oligomeric matrix protein (COMP)	1101:1146	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	58	theme	oligomeric	1115:1124	arg1	COMP					1142:1145	COMP	1142:1145	COMP	1142:1145	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	3	59	theme	cells	525:529	arg1	differentiation					477:491	the chondrogenic differentiation	460:491	the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	460:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	8	60	theme	cartilage	1438:1446	arg1	explants					1448:1455	the OA cartilage explants	1431:1455	the OA cartilage explants	1431:1455	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	7	61	theme	GAGs	1334:1337	arg1	release					1314:1320	the release	1310:1320	the release of COMP and GAGs from the cartilage explants	1310:1365	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	3	62	theme	CS-tyramine-gelatin	559:577	arg1	hydrogel					592:599	CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel	559:599	CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	559:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	5	63	theme	collagen	924:931	arg1	staining					936:943	immunohistochemical collagen II staining	904:943	immunohistochemical collagen II staining	904:943	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	5	63	theme	collagen	924:931	arg1	hydrogel					894:901	CS-Tyr/Gel hydrogel	883:901	CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining)	883:944	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	7	64	from	explants	1358:1365	arg1	release					1314:1320	the release	1310:1320	the release of COMP and GAGs from the cartilage explants	1310:1365	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	6	65	theme	human	1014:1018	arg1	explants					1033:1040	the human OA cartilage explants	1010:1040	the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1010:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	7	66	theme	COMP	1325:1328	arg1	release					1314:1320	the release	1310:1320	the release of COMP and GAGs from the cartilage explants	1310:1365	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	1	67	theme	matrix	190:195	arg1	integrity					203:211	extracellular matrix (ECM) integrity	176:211	extracellular matrix (ECM) integrity	176:211	The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA).					
36834862	5	68	theme	BM-MSCs	872:878	arg1	differentiation					853:867	the chondrogenic differentiation	836:867	the chondrogenic differentiation of BM-MSCs	836:878	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	8	69	theme	damaging	1466:1473	arg1	effects					1475:1481	the damaging effects	1462:1481	the damaging effects of external mechanical stimuli	1462:1512	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	5	70	theme	CS-Tyr/Gel	883:892	arg1	staining					936:943	immunohistochemical collagen II staining	904:943	immunohistochemical collagen II staining	904:943	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	5	70	theme	CS-Tyr/Gel	883:892	arg1	hydrogel					894:901	CS-Tyr/Gel hydrogel	883:901	CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining)	883:944	The applied mild mechanical load stimulated the chondrogenic differentiation of BM-MSCs in CS-Tyr/Gel hydrogel (immunohistochemical collagen II staining).					
36834862	6	71	theme	negative	991:998	arg1	effect					1000:1005	a negative effect	989:1005	a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	989:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	72	from	effect	1000:1005	arg1	explants					1033:1040	the human OA cartilage explants	1010:1040	the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1010:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	8	73	theme	mechanical	1495:1504	arg1	stimuli					1506:1512	external mechanical stimuli	1486:1512	external mechanical stimuli	1486:1512	Data suggest that the CS-Tyr/Gel/BM-MSCs composite can protect the OA cartilage explants from the damaging effects of external mechanical stimuli.					
36834862	7	74	theme	explants	1291:1298	arg1	top					1267:1269	the top	1263:1269	the top of the OA cartilage explants	1263:1298	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	0	75	theme	Sulfate-Tyramine-Based	12:33	arg1	Hydrogels					35:43	Chondroitin Sulfate-Tyramine-Based Hydrogels	0:43	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.	0:72	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.					
36834862	7	76	theme	OA	1278:1279	arg1	explants					1291:1298	the OA cartilage explants	1274:1298	the OA cartilage explants	1274:1298	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	6	77	contain	had	985:987	arg1	load					980:983	the stronger mechanical load	956:983	the stronger mechanical load	956:983	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	77	contain	had	985:987	arg2	effect					1000:1005	a negative effect	989:1005	a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	989:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	4	78	theme	cartilage	772:780	arg1	explants					782:789	cartilage explants	772:789	cartilage explants	772:789	The CS-Tyr/Gel/BM-MSCs composite showed excellent biointegration on cartilage explants.					
36834862	2	79	theme	ECM	383:385	arg1	sulfate					265:271	Chondroitin sulfate	253:271	Chondroitin sulfate (CS)	253:276	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	79	theme	ECM	383:385	arg1	member					283:288	a member	281:288	a member of the highly sulfated glycosaminoglycans (GAGs)	281:337	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	79	theme	ECM	383:385	arg1	component					353:361	a primary component	343:361	a primary component of cartilage tissue ECM	343:385	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	2	80	theme	cartilage	366:374	arg1	ECM					383:385	cartilage tissue ECM	366:385	cartilage tissue ECM	366:385	Chondroitin sulfate (CS) is a member of the highly sulfated glycosaminoglycans (GAGs) and a primary component of cartilage tissue ECM.					
36834862	0	81	theme	Tissue	59:64	arg1	Repair					66:71	Cartilage Tissue Repair	49:71	Cartilage Tissue Repair	49:71	Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair.					
36834862	6	82	theme	cartilage	1023:1031	arg1	explants					1033:1040	the human OA cartilage explants	1010:1040	the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs	1010:1155	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	3	83	theme	CS-Tyr/Gel	580:589	arg1	hydrogel					592:599	CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel	559:599	CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro	559:701	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	7	84	theme	composite	1250:1258	arg1	application					1212:1222	the application	1208:1222	the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants	1208:1298	Finally, the application of the CS-Tyr/Gel/BM-MSCs composite on the top of the OA cartilage explants decreased the release of COMP and GAGs from the cartilage explants.					
36834862	3	85	theme	mechanical	441:450	arg1	load					452:455	mechanical load	441:455	mechanical load	441:455	In this study, we aimed to investigate the effect of mechanical load on the chondrogenic differentiation of bone marrow mesenchymal stem cells (BM-MCSs) encapsulated into CS-tyramine-gelatin (CS-Tyr/Gel) hydrogel in order to evaluate the suitability of this composite for OA cartilage regeneration studies in vitro.					
36834862	4	86	theme	excellent	744:752	arg1	biointegration					754:767	excellent biointegration	744:767	excellent biointegration on cartilage explants	744:789	The CS-Tyr/Gel/BM-MSCs composite showed excellent biointegration on cartilage explants.					
36834862	6	87	theme	cartilage	1105:1113	arg1	protein					1133:1139	the cartilage oligomeric matrix protein	1101:1139	the cartilage oligomeric matrix protein (COMP)	1101:1146	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36834862	6	87	theme	cartilage	1105:1113	arg1	COMP					1142:1145	COMP	1142:1145	COMP	1142:1145	However, the stronger mechanical load had a negative effect on the human OA cartilage explants evaluated by the higher release of ECM components, such as the cartilage oligomeric matrix protein (COMP) and GAGs, compared to the not-compressed explants.					
36561308	6	0	theme	independent	853:863	arg1	CD					797:798	CD	797:798	CD	797:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	variables					865:873	the independent variables X1, X2, and X3	849:888	the independent variables X1, X2, and X3	849:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	X3					887:888	X3	887:888	X3	887:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	amount					801:806	amount	801:806	amount of polymer	801:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	type					832:835	polymer type	824:835	polymer type	824:835	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	X1					875:876	X1	875:876	X1	875:876	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	amount					787:792	The amount	783:792	The amount of CD	783:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	X2					879:880	X2	879:880	X2	879:880	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	0	theme	independent	853:863	arg1	polymer					811:817	polymer	811:817	polymer	811:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	4	1	used	used	537:540	arg2	We					534:535	We	534:535	We	534:535	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	7	2	theme	RIV	905:907	arg1	rate					941:944	RIV solubility (Y1) and dissolution rate	905:944	rate	941:944	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	2	theme	RIV	905:907	arg1	variables					1023:1031	response variables	1014:1031	response variables	1014:1031	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	2	theme	RIV	905:907	arg1	Y1					921:922	RIV solubility (Y1) and dissolution rate	905:944	Y1	921:922	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	1	3	dep	Purpose	113:119	arg1	aimed					132:136	aimed	132:136	aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV)	132:286	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	9	4	theme	amorphous	1261:1269	arg1	form					1271:1274	an amorphous form	1258:1274	an amorphous form	1258:1274	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	11	5	theme	high-dose	1494:1502	arg1	RIV					1504:1506	high-dose RIV	1494:1506	high-dose RIV	1494:1506	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	11	6	dep	administration	1619:1632	arg1	mistake					1634:1640	mistake	1634:1640	the patient's administration mistake	1605:1640	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	6	7	theme	CD	797:798	arg1	CD					797:798	CD	797:798	CD	797:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	7	theme	CD	797:798	arg1	variables					865:873	the independent variables X1, X2, and X3	849:888	the independent variables X1, X2, and X3	849:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	7	theme	CD	797:798	arg1	amount					801:806	amount	801:806	amount of polymer	801:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	7	theme	CD	797:798	arg1	type					832:835	polymer type	824:835	polymer type	824:835	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	7	theme	CD	797:798	arg1	amount					787:792	The amount	783:792	The amount of CD	783:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	7	theme	CD	797:798	arg1	polymer					811:817	polymer	811:817	polymer	811:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	9	8	attach	present	1247:1253	arg1	form					1271:1274	an amorphous form	1258:1274	an amorphous form	1258:1274	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	9	8	attach	present	1247:1253	arg2	RIV					1218:1220	RIV	1218:1220	RIV in the R-C-P complex	1218:1241	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	1	9	theme	reproducibility	186:200	arg1	convenience					152:162	the convenience	148:162	the convenience of administration and reproducibility of efficacy	148:212	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	1	10	theme	rivaroxaban	270:280	arg1	solubility					256:265	the solubility	252:265	the solubility of rivaroxaban (RIV)	252:286	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	3	11	theme	low	456:458	arg1	solubility					460:469	a very low solubility	449:469	a very low solubility; therefore, it must be administered with a meal at high doses	449:531	However, RIV has a very low solubility; therefore, it must be administered with a meal at high doses.					
36561308	10	12	theme	dissolution	1349:1359	arg1	rate					1361:1364	a 100% dissolution rate	1342:1364	a 100% dissolution rate	1342:1364	Unlike commercial products, it showed a 100% dissolution rate.					
36561308	7	13	theme	pH	983:984	arg1	Y3					998:999	Y3	998:999	Y3	998:999	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	13	theme	pH	983:984	arg1	medium					990:995	pH 1.2 medium	983:995	pH 1.2 medium (Y3)	983:1000	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	3	14	theme	high	522:525	arg1	doses					527:531	high doses	522:531	high doses	522:531	However, RIV has a very low solubility; therefore, it must be administered with a meal at high doses.					
36561308	11	15	theme	pH.	1456:1458	arg1	Conclusion					1460:1469	pH. Conclusion	1456:1469	pH. Conclusion	1456:1469	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	6	16	dep	variables	865:873	arg1	X2					879:880	X2	879:880	X2	879:880	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	16	dep	variables	865:873	arg1	X3					887:888	X3	887:888	X3	887:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	16	dep	variables	865:873	arg1	X1					875:876	X1	875:876	X1	875:876	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	16	dep	variables	865:873	arg1	variables					865:873	the independent variables X1, X2, and X3	849:888	the independent variables X1, X2, and X3	849:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	7	17	theme	dissolution	929:939	arg1	rate					941:944	RIV solubility (Y1) and dissolution rate	905:944	rate	941:944	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	17	theme	dissolution	929:939	arg1	variables					1023:1031	response variables	1014:1031	response variables	1014:1031	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	17	theme	dissolution	929:939	arg1	Y1					921:922	RIV solubility (Y1) and dissolution rate	905:944	Y1	921:922	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	11	18	theme	R-C-P	1371:1375	arg1	formulation					1385:1395	The R-C-P complex formulation	1367:1395	The R-C-P complex formulation	1367:1395	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	2	19	theme	Methods	289:295	arg1	antagonist					320:329	a non-vitamin K antagonist	304:329	a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa	304:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	2	19	theme	Methods	289:295	arg1	RIV					297:299	Methods RIV	289:299	Methods RIV	289:299	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	5	20	theme	factor	706:711	arg1	effect					691:696	the effect	687:696	the effect of each factor on RIV solubility	687:729	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	11	21	theme	complex	1377:1383	arg1	formulation					1385:1395	The R-C-P complex formulation	1367:1395	The R-C-P complex formulation	1367:1395	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	2	22	theme	coagulation	409:419	arg1	Xa					428:429	coagulation factor Xa	409:429	coagulation factor Xa	409:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	5	23	theme	complex	762:768	arg1	formulation					770:780	an optimal R-C-P complex formulation	745:780	an optimal R-C-P complex formulation	745:780	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	8	24	theme	solubilization	1065:1078	arg1	effect					1080:1085	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	11	25	theme	drug	1586:1589	arg1	effect					1591:1596	the drug effect	1582:1596	the drug effect	1582:1596	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	1	26	theme	efficacy	205:212	arg1	administration					167:180	administration	167:180	administration	167:180	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	1	26	theme	efficacy	205:212	arg1	reproducibility					186:200	reproducibility	186:200	reproducibility	186:200	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	6	27	theme	polymer	824:830	arg1	CD					797:798	CD	797:798	CD	797:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	27	theme	polymer	824:830	arg1	variables					865:873	the independent variables X1, X2, and X3	849:888	the independent variables X1, X2, and X3	849:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	27	theme	polymer	824:830	arg1	amount					801:806	amount	801:806	amount of polymer	801:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	27	theme	polymer	824:830	arg1	type					832:835	polymer type	824:835	polymer type	824:835	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	27	theme	polymer	824:830	arg1	amount					787:792	The amount	783:792	The amount of CD	783:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	27	theme	polymer	824:830	arg1	polymer					811:817	polymer	811:817	polymer	811:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	5	28	theme	RIV	716:718	arg1	solubility					720:729	RIV solubility	716:729	RIV solubility	716:729	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	2	29	theme	K	318:318	arg1	antagonist					320:329	a non-vitamin K antagonist	304:329	a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa	304:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	2	29	theme	K	318:318	arg1	RIV					297:299	Methods RIV	289:299	Methods RIV	289:299	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	11	30	theme	%	1432:1432	arg1	release					1434:1440	100% release	1429:1440	100% release	1429:1440	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	8	31	theme	Results	1034:1040	arg1	effect					1080:1085	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	10	32	theme	commercial	1311:1320	arg1	products					1322:1329	commercial products	1311:1329	commercial products	1311:1329	Unlike commercial products, it showed a 100% dissolution rate.					
36561308	11	33	theme	high	1405:1408	arg1	solubility					1414:1423	high RIV solubility	1405:1423	high RIV solubility	1405:1423	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	2	34	theme	non-vitamin	306:316	arg1	antagonist					320:329	a non-vitamin K antagonist	304:329	a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa	304:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	2	34	theme	non-vitamin	306:316	arg1	RIV					297:299	Methods RIV	289:299	Methods RIV	289:299	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	8	35	theme	efficient	1051:1059	arg1	solubilization					1065:1078	The most efficient RIV solubilization	1042:1078	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	8	36	theme	physicochemical	1149:1163	arg1	properties					1165:1174	physicochemical properties	1149:1174	physicochemical properties	1149:1174	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	10	37	theme	%	1347:1347	arg1	rate					1361:1364	a 100% dissolution rate	1342:1364	a 100% dissolution rate	1342:1364	Unlike commercial products, it showed a 100% dissolution rate.					
36561308	9	38	theme	high	1287:1290	arg1	solubility					1292:1301	high solubility	1287:1301	high solubility	1287:1301	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	8	39	theme	dissolution	1180:1190	arg1	parameters					1192:1201	dissolution parameters	1180:1201	dissolution parameters	1180:1201	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	9	40	located	present	1247:1253	arg1	form					1271:1274	an amorphous form	1258:1274	an amorphous form	1258:1274	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	9	40	located	present	1247:1253	arg2	RIV					1218:1220	RIV	1218:1220	RIV in the R-C-P complex	1218:1241	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	7	41	from	Y1	921:922	arg1	Y3					998:999	Y3	998:999	Y3	998:999	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	41	from	Y1	921:922	arg1	medium					990:995	pH 1.2 medium	983:995	pH 1.2 medium (Y3)	983:1000	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	41	from	Y1	921:922	arg1	Y2					975:976	Y2	975:976	Y2	975:976	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	41	from	Y1	921:922	arg1	medium					967:972	pH 4.5 medium	960:972	pH 4.5 medium (Y2)	960:977	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	42	theme	response	1014:1021	arg1	rate					941:944	RIV solubility (Y1) and dissolution rate	905:944	rate	941:944	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	42	theme	response	1014:1021	arg1	variables					1023:1031	response variables	1014:1031	response variables	1014:1031	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	42	theme	response	1014:1021	arg1	Y1					921:922	RIV solubility (Y1) and dissolution rate	905:944	Y1	921:922	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	10	43	theme	100	1344:1346	arg1	%					1347:1347	%	1347:1347	%	1347:1347	Unlike commercial products, it showed a 100% dissolution rate.					
36561308	2	44	dep	anticoagulants	336:349	arg1	antagonist					320:329	a non-vitamin K antagonist	304:329	a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa	304:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	2	44	dep	anticoagulants	336:349	arg1	RIV					297:299	Methods RIV	289:299	Methods RIV	289:299	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	0	45	theme	Triple	60:65	arg1	Formulation					75:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	4	46	theme	R-C-P	625:629	arg1	complex					616:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex	542:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex)	542:638	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	4	46	theme	R-C-P	625:629	arg1	complex					631:637	R-C-P complex	625:637	R-C-P complex	625:637	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	8	47	theme	HPMC	1134:1137	arg1	2208					1139:1142	HPMC 2208	1134:1142	HPMC 2208	1134:1142	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	0	48	theme	Rivaroxaban-Cyclodextrin-Polymer	27:58	arg1	Formulation					75:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	5	49	theme	optimal	748:754	arg1	formulation					770:780	an optimal R-C-P complex formulation	745:780	an optimal R-C-P complex formulation	745:780	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	6	50	theme	polymer	811:817	arg1	CD					797:798	CD	797:798	CD	797:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	50	theme	polymer	811:817	arg1	variables					865:873	the independent variables X1, X2, and X3	849:888	the independent variables X1, X2, and X3	849:888	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	50	theme	polymer	811:817	arg1	amount					801:806	amount	801:806	amount of polymer	801:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	50	theme	polymer	811:817	arg1	type					832:835	polymer type	824:835	polymer type	824:835	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	50	theme	polymer	811:817	arg1	amount					787:792	The amount	783:792	The amount of CD	783:798	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	6	50	theme	polymer	811:817	arg1	polymer					811:817	polymer	811:817	polymer	811:817	The amount of CD, amount of polymer, and polymer type were set as the independent variables X1, X2, and X3, respectively.					
36561308	2	51	theme	factor	421:426	arg1	Xa					428:429	coagulation factor Xa	409:429	coagulation factor Xa	409:429	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	0	52	theme	Formulation	75:85	arg1	Optimization					11:22	Optimization	11:22	Optimization	11:22	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	0	52	theme	Formulation	75:85	arg1	Design					0:5	Design	0:5	Design	0:5	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	8	53	theme	RIV	1061:1063	arg1	solubilization					1065:1078	The most efficient RIV solubilization	1042:1078	Results The most efficient RIV solubilization effect	1034:1085	Results The most efficient RIV solubilization effect was obtained from the composition using CD and HPMC 2208, and physicochemical properties and dissolution parameters were analyzed.					
36561308	0	54	with	Optimization	11:22	arg1	Solubility					101:110	Improved Solubility	92:110	Improved Solubility	92:110	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	7	55	theme	pH	960:961	arg1	Y2					975:976	Y2	975:976	Y2	975:976	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	55	theme	pH	960:961	arg1	medium					967:972	pH 4.5 medium	960:972	pH 4.5 medium (Y2)	960:977	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	0	56	theme	Complex	67:73	arg1	Formulation					75:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation	27:85	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	9	57	theme	R-C-P	1229:1233	arg1	complex					1235:1241	the R-C-P complex	1225:1241	the R-C-P complex	1225:1241	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	9	58	from	form	1271:1274	arg1	present					1247:1253	present	1247:1253	present	1247:1253	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	9	59	from	RIV	1218:1220	arg1	complex					1235:1241	the R-C-P complex	1225:1241	the R-C-P complex	1225:1241	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	11	60	theme	100	1429:1431	arg1	%					1432:1432	%	1432:1432	%	1432:1432	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	11	61	theme	RIV	1410:1412	arg1	solubility					1414:1423	high RIV solubility	1405:1423	high RIV solubility	1405:1423	The R-C-P complex formulation secured high RIV solubility and 100% release regardless of pH. Conclusion The results imply that high-dose RIV can be administered regardless of the meal, reducing the risk of changing the drug effect due to the patient's administration mistake.					
36561308	0	62	with	Design	0:5	arg1	Solubility					101:110	Improved Solubility	92:110	Improved Solubility	92:110	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	2	63	theme	oral	331:334	arg1	anticoagulants					336:349	oral anticoagulants	331:349	oral anticoagulants	331:349	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	4	64	theme	-water-soluble	586:599	arg1	complex					616:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex	542:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex)	542:638	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	4	64	theme	-water-soluble	586:599	arg1	complex					631:637	R-C-P complex	625:637	R-C-P complex	625:637	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	9	65	from	present	1247:1253	arg1	form					1271:1274	an amorphous form	1258:1274	an amorphous form	1258:1274	RIV in the R-C-P complex was present in an amorphous form and showed high solubility.					
36561308	5	66	from	effect	691:696	arg1	solubility					720:729	RIV solubility	716:729	RIV solubility	716:729	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	7	67	theme	solubility	909:918	arg1	rate					941:944	RIV solubility (Y1) and dissolution rate	905:944	rate	941:944	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	67	theme	solubility	909:918	arg1	variables					1023:1031	response variables	1014:1031	response variables	1014:1031	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	67	theme	solubility	909:918	arg1	Y1					921:922	RIV solubility (Y1) and dissolution rate	905:944	Y1	921:922	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	1	68	theme	administration	167:180	arg1	convenience					152:162	the convenience	148:162	the convenience of administration and reproducibility of efficacy	148:212	Purpose This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV).					
36561308	7	69	from	rate	941:944	arg1	Y3					998:999	Y3	998:999	Y3	998:999	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	69	from	rate	941:944	arg1	medium					990:995	pH 1.2 medium	983:995	pH 1.2 medium (Y3)	983:1000	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	69	from	rate	941:944	arg1	Y2					975:976	Y2	975:976	Y2	975:976	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	7	69	from	rate	941:944	arg1	medium					967:972	pH 4.5 medium	960:972	pH 4.5 medium (Y2)	960:977	RIV solubility (Y1) and dissolution rate for 45 min in pH 4.5 medium (Y2) and pH 1.2 medium (Y3) were set as response variables.					
36561308	0	70	theme	Improved	92:99	arg1	Solubility					101:110	Improved Solubility	92:110	Improved Solubility	92:110	Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility.					
36561308	3	71	contain	has	445:447	arg2	solubility					460:469	a very low solubility	449:469	a very low solubility; therefore, it must be administered with a meal at high doses	449:531	However, RIV has a very low solubility; therefore, it must be administered with a meal at high doses.					
36561308	3	71	contain	has	445:447	arg1	RIV					441:443	RIV	441:443	RIV	441:443	However, RIV has a very low solubility; therefore, it must be administered with a meal at high doses.					
36561308	3	72	dep	solubility	460:469	arg1	administered					494:505	administered	494:505	must be administered with a meal at high doses	486:531	However, RIV has a very low solubility; therefore, it must be administered with a meal at high doses.					
36561308	4	73	theme	triple	609:614	arg1	complex					616:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex	542:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex)	542:638	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	4	73	theme	triple	609:614	arg1	complex					631:637	R-C-P complex	625:637	R-C-P complex	625:637	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	5	74	theme	R-C-P	756:760	arg1	formulation					770:780	an optimal R-C-P complex formulation	745:780	an optimal R-C-P complex formulation	745:780	Using Minitab, we evaluated the effect of each factor on RIV solubility and developed an optimal R-C-P complex formulation.					
36561308	2	75	theme	coagulation	367:377	arg1	effect					379:384	a coagulation effect	365:384	a coagulation effect	365:384	Methods RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting coagulation factor Xa.					
36561308	4	76	theme	polymer	601:607	arg1	complex					616:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex	542:622	a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex)	542:638	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
36561308	4	76	theme	polymer	601:607	arg1	complex					631:637	R-C-P complex	625:637	R-C-P complex	625:637	We used a drug- hydroxypropyl-beta-cyclodextrin (CD)-water-soluble polymer triple complex (R-C-P complex) to solubilize RIV.					
35405155	0	0	theme	microphylla	83:93	arg1	Turcz					95:99	Premna microphylla Turcz leaves	76:106	Premna microphylla Turcz leaves	76:106	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	10	1	theme	film	1398:1401	arg1	activity					1371:1378	the antibacterial activity	1353:1378	the antibacterial activity of the fabricated film against Staphylococcus aureus	1353:1431	Furthermore, adding ZnO to the nano-formula improved the antibacterial activity of the fabricated film against Staphylococcus aureus.					
35405155	8	2	from	break	1153:1157	arg1	Elongation					1134:1143	Elongation	1134:1143	Elongation (E%) at break	1134:1157	Elongation (E%) at break was the best for each CP10 (74.9) and CPN0.5 (73.03).					
35405155	8	2	from	break	1153:1157	arg1	%					1147:1147	E%	1146:1147	E%	1146:1147	Elongation (E%) at break was the best for each CP10 (74.9) and CPN0.5 (73.03).					
35405155	8	2	from	break	1153:1157	arg1	best					1167:1170	best	1167:1170	best	1167:1170	Elongation (E%) at break was the best for each CP10 (74.9) and CPN0.5 (73.03).					
35405155	11	3	theme	packaging	1534:1542	arg1	applications					1544:1555	packaging applications	1534:1555	packaging applications	1534:1555	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	9	4	theme	nanofilm	1269:1276	arg1	ratio					1293:1297	the nanofilm water swelling ratio	1265:1297	the nanofilm water swelling ratio	1265:1297	Moreover, ZnO can enhance the nanofilm activity and the nanofilm water swelling ratio.					
35405155	0	5	theme	Premna	76:81	arg1	Turcz					95:99	Premna microphylla Turcz leaves	76:106	Premna microphylla Turcz leaves	76:106	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	11	6	theme	promising	1487:1495	arg1	prospects					1497:1505	promising prospects	1487:1505	promising prospects as antibacterial agents in packaging applications	1487:1555	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	4	7	theme	circle	580:585	arg1	method					587:592	the antibacterial circle method	562:592	the antibacterial circle method	562:592	The antibacterial activity of the nanofilm was determined using the antibacterial circle method.					
35405155	5	8	theme	ultraviolet	727:737	arg1	light					739:743	ultraviolet light	727:743	ultraviolet light	727:743	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	4	9	theme	antibacterial	502:514	arg1	activity					516:523	The antibacterial activity	498:523	The antibacterial activity of the nanofilm	498:539	The antibacterial activity of the nanofilm was determined using the antibacterial circle method.					
35405155	5	10	theme	nanofilm	656:663	arg1	color					665:669	nanofilm color	656:669	nanofilm color	656:669	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	1	11	theme	ZnO-carboxymethyl	260:276	arg1	cellulose					278:286	ZnO-carboxymethyl cellulose	260:286	ZnO-carboxymethyl cellulose	260:286	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	0	12	theme	Turcz	95:99	arg1	pectin					66:71	extracted pectin	56:71	extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose	56:134	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	5	13	theme	permeability	709:720	arg1	permeability					745:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability	652:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm	652:772	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	5	14	theme	color	665:669	arg1	permeability					745:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability	652:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm	652:772	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	2	15	theme	rheological	293:303	arg1	properties					318:327	The rheological and physical properties	289:327	The rheological and physical properties of fabricated nano-ZnO films	289:356	The rheological and physical properties of fabricated nano-ZnO films were studied.					
35405155	2	16	theme	nano-ZnO	343:350	arg1	films					352:356	fabricated nano-ZnO films	332:356	fabricated nano-ZnO films	332:356	The rheological and physical properties of fabricated nano-ZnO films were studied.					
35405155	0	17	theme	carboxymethyl	112:124	arg1	cellulose					126:134	carboxymethyl cellulose	112:134	carboxymethyl cellulose	112:134	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	6	18	theme	Tensile	815:821	arg1	strength					823:830	the optimized Tensile strength	801:830	the optimized Tensile strength (TS) of 4.50 Mpa	801:847	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	6	18	theme	Tensile	815:821	arg1	TS					833:834	TS	833:834	TS	833:834	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	9	19	theme	water	1278:1282	arg1	ratio					1293:1297	the nanofilm water swelling ratio	1265:1297	the nanofilm water swelling ratio	1265:1297	Moreover, ZnO can enhance the nanofilm activity and the nanofilm water swelling ratio.					
35405155	1	20	theme	pectin	175:180	arg1	nano-films					182:191	pectin nano-films	175:191	pectin nano-films	175:191	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	3	21	theme	Spectroscopy	372:383	arg1	FT-IR					385:389	Spectroscopy FT-IR	372:389	Spectroscopy FT-IR	372:389	Spectroscopy FT-IR, microscopic study (SEM), thermogravimetry (TG), and XRD were applied to characterize the fabricated film.					
35405155	6	22	theme	optimized	805:813	arg1	strength					823:830	the optimized Tensile strength	801:830	the optimized Tensile strength (TS) of 4.50 Mpa	801:847	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	6	22	theme	optimized	805:813	arg1	TS					833:834	TS	833:834	TS	833:834	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	0	23	dep	Turcz	95:99	arg1	leaves					101:106	leaves	101:106	leaves	101:106	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	7	24	theme	CPN1	1109:1112	arg1	treatments					1122:1131	CPN1 (30.98) treatments	1109:1131	CPN1 (30.98) treatments	1109:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	10	25	theme	fabricated	1387:1396	arg1	film					1398:1401	the fabricated film	1383:1401	the fabricated film	1383:1401	Furthermore, adding ZnO to the nano-formula improved the antibacterial activity of the fabricated film against Staphylococcus aureus.					
35405155	5	26	theme	PMTP	636:639	arg1	addition					624:631	the addition	620:631	the addition of PMTP	620:639	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	2	27	theme	fabricated	332:341	arg1	films					352:356	fabricated nano-ZnO films	332:356	fabricated nano-ZnO films	332:356	The rheological and physical properties of fabricated nano-ZnO films were studied.					
35405155	11	28	contain	possess	1479:1485	arg1	nanofilms					1442:1450	nanofilms	1442:1450	nanofilms fabricated of PMTP and ZnO	1442:1477	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	11	28	contain	possess	1479:1485	arg2	prospects					1497:1505	promising prospects	1487:1505	promising prospects as antibacterial agents in packaging applications	1487:1555	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	1	29	theme	Premna	198:203	arg1	PMTP					224:227	Premna microphylla Turcz (PMTP) leaves	198:235	Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose	198:286	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	3	30	theme	microscopic	392:402	arg1	SEM					411:413	SEM	411:413	SEM	411:413	Spectroscopy FT-IR, microscopic study (SEM), thermogravimetry (TG), and XRD were applied to characterize the fabricated film.					
35405155	3	30	theme	microscopic	392:402	arg1	study					404:408	microscopic study	392:408	microscopic study (SEM)	392:414	Spectroscopy FT-IR, microscopic study (SEM), thermogravimetry (TG), and XRD were applied to characterize the fabricated film.					
35405155	5	31	theme	air	705:707	arg1	permeability					709:720	air permeability	705:720	air permeability	705:720	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	9	32	theme	swelling	1284:1291	arg1	ratio					1293:1297	the nanofilm water swelling ratio	1265:1297	the nanofilm water swelling ratio	1265:1297	Moreover, ZnO can enhance the nanofilm activity and the nanofilm water swelling ratio.					
35405155	1	33	theme	microphylla	205:215	arg1	PMTP					224:227	Premna microphylla Turcz (PMTP) leaves	198:235	Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose	198:286	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	4	34	theme	antibacterial	566:578	arg1	method					587:592	the antibacterial circle method	562:592	the antibacterial circle method	562:592	The antibacterial activity of the nanofilm was determined using the antibacterial circle method.					
35405155	0	35	theme	cellulose	126:134	arg1	pectin					66:71	extracted pectin	56:71	extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose	56:134	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	2	36	theme	physical	309:316	arg1	properties					318:327	The rheological and physical properties	289:327	The rheological and physical properties of fabricated nano-ZnO films	289:356	The rheological and physical properties of fabricated nano-ZnO films were studied.					
35405155	1	37	theme	Turcz	217:221	arg1	PMTP					224:227	Premna microphylla Turcz (PMTP) leaves	198:235	Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose	198:286	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	11	38	from	prospects	1497:1505	arg1	applications					1544:1555	packaging applications	1534:1555	packaging applications	1534:1555	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	7	39	theme	significant	1064:1074	arg1	differences					1076:1086	no significant differences	1061:1086	no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments	1061:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	0	40	theme	ZnO	36:38	arg1	characterization					16:31	characterization	16:31	characterization	16:31	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	0	40	theme	ZnO	36:38	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	7	41	theme	highest	1005:1011	arg1	41.62					1020:1024	41.62	1020:1024	41.62	1020:1024	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	41	theme	highest	1005:1011	arg1	value					1013:1017	the highest value	1001:1017	the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments	1001:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	6	42	theme	significant	850:860	arg1	differences					862:872	significant differences	850:872	significant differences	850:872	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	0	43	theme	extracted	56:64	arg1	pectin					66:71	extracted pectin	56:71	extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose	56:134	Fabrication and characterization of ZnO nanofilms using extracted pectin of Premna microphylla Turcz leaves and carboxymethyl cellulose.					
35405155	7	44	theme	30.98	1115:1119	arg1	treatments					1122:1131	CPN1 (30.98) treatments	1109:1131	CPN1 (30.98) treatments	1109:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	3	45	theme	fabricated	481:490	arg1	film					492:495	the fabricated film	477:495	the fabricated film	477:495	Spectroscopy FT-IR, microscopic study (SEM), thermogravimetry (TG), and XRD were applied to characterize the fabricated film.					
35405155	7	46	with	differences	1076:1086	arg1	CPN3					1093:1096	CPN3 (29.7)	1093:1103	CPN3 (29.7)	1093:1103	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	46	with	differences	1076:1086	arg1	treatments					1122:1131	CPN1 (30.98) treatments	1109:1131	CPN1 (30.98) treatments	1109:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	5	47	theme	water	672:676	arg1	solubility/hydrophilicity					678:702	water solubility/hydrophilicity	672:702	water solubility/hydrophilicity	672:702	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	6	48	theme	Mpa	845:847	arg1	strength					823:830	the optimized Tensile strength	801:830	the optimized Tensile strength (TS) of 4.50 Mpa	801:847	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	6	48	theme	Mpa	845:847	arg1	TS					833:834	TS	833:834	TS	833:834	Treatment CPN0.5 achieved the optimized Tensile strength (TS) of 4.50 Mpa, significant differences compared to CPN2 (3.99 Mpa) and CPN1 (3.65 Mpa).					
35405155	7	49	theme	lowest	964:969	arg1	29.35					982:986	29.35	982:986	29.35	982:986	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	49	theme	lowest	964:969	arg1	value					975:979	the lowest WVP value	960:979	the lowest WVP value (29.35)	960:987	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	50	theme	CPN0.5	1039:1044	arg1	treatment					1046:1054	CPN0.5 treatment	1039:1054	CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments	1039:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	4	51	theme	nanofilm	532:539	arg1	activity					516:523	The antibacterial activity	498:523	The antibacterial activity of the nanofilm	498:539	The antibacterial activity of the nanofilm was determined using the antibacterial circle method.					
35405155	5	52	theme	solubility/hydrophilicity	678:702	arg1	permeability					745:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability	652:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm	652:772	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	7	53	theme	WVP	971:973	arg1	29.35					982:986	29.35	982:986	29.35	982:986	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	53	theme	WVP	971:973	arg1	value					975:979	the lowest WVP value	960:979	the lowest WVP value (29.35)	960:987	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	2	54	theme	films	352:356	arg1	properties					318:327	The rheological and physical properties	289:327	The rheological and physical properties of fabricated nano-ZnO films	289:356	The rheological and physical properties of fabricated nano-ZnO films were studied.					
35405155	10	55	theme	antibacterial	1357:1369	arg1	activity					1371:1378	the antibacterial activity	1353:1378	the antibacterial activity of the fabricated film against Staphylococcus aureus	1353:1431	Furthermore, adding ZnO to the nano-formula improved the antibacterial activity of the fabricated film against Staphylococcus aureus.					
35405155	1	56	dep	PMTP	224:227	arg1	leaves					230:235	leaves	230:235	leaves	230:235	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	1	57	theme	current	141:147	arg1	study					149:153	The current study	137:153	The current study	137:153	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	1	58	theme	cellulose	278:286	arg1	combination					245:255	a combination	243:255	a combination of ZnO-carboxymethyl cellulose	243:286	The current study sought to fabricate pectin nano-films from Premna microphylla Turcz (PMTP) leaves using a combination of ZnO-carboxymethyl cellulose.					
35405155	11	59	theme	antibacterial	1510:1522	arg1	agents					1524:1529	antibacterial agents	1510:1529	antibacterial agents	1510:1529	In sum, nanofilms fabricated of PMTP and ZnO possess promising prospects as antibacterial agents in packaging applications.					
35405155	8	60	theme	E	1146:1146	arg1	Elongation					1134:1143	Elongation	1134:1143	Elongation (E%) at break	1134:1157	Elongation (E%) at break was the best for each CP10 (74.9) and CPN0.5 (73.03).					
35405155	8	60	theme	E	1146:1146	arg1	%					1147:1147	E%	1146:1147	E%	1146:1147	Elongation (E%) at break was the best for each CP10 (74.9) and CPN0.5 (73.03).					
35405155	9	61	theme	nanofilm	1243:1250	arg1	activity					1252:1259	the nanofilm activity	1239:1259	the nanofilm activity	1239:1259	Moreover, ZnO can enhance the nanofilm activity and the nanofilm water swelling ratio.					
35405155	5	62	theme	nanofilm	765:772	arg1	permeability					745:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability	652:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm	652:772	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35405155	7	63	theme	treatment	936:944	arg1	CPN1					946:949	treatment CPN1	936:949	treatment CPN1	936:949	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	7	64	with	treatment	1046:1054	arg1	differences					1076:1086	no significant differences	1061:1086	no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments	1061:1131	In addition, treatment CPN1 achieved the lowest WVP value (29.35) compared to the highest value (41.62) achieved by CPN0.5 treatment with no significant differences with CPN3 (29.7) and CPN1 (30.98) treatments.					
35405155	5	65	theme	light	739:743	arg1	permeability					745:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability	652:756	the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm	652:772	The findings showed that the addition of PMTP can reduce the nanofilm color, water solubility/hydrophilicity, air permeability, and ultraviolet light permeability of the nanofilm.					
35487110	2	0	theme	type-II	669:675	arg1	heterojunction					677:690	Bi2WO6/SrTiO3 type-II heterojunction	655:690	Bi2WO6/SrTiO3 type-II heterojunction	655:690	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	6	1	theme	practical	1411:1419	arg1	applications					1421:1432	practical applications	1411:1432	practical applications	1411:1432	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	4	2	theme	other	978:982	arg1	papers					992:997	other control papers	978:997	other control papers	978:997	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	4	3	theme	Xe	1153:1154	arg1	irradiation					1161:1171	Xe lamp irradiation	1153:1171	Xe lamp irradiation	1153:1171	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	2	4	dep	structure	610:618	arg1	the					594:596	the	594:596	the	594:596	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	2	5	theme	scheme	699:704	arg1	heterojunction					706:719	Z scheme heterojunction	697:719	Z scheme heterojunction	697:719	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	6	6	theme	cellulose	1287:1295	arg1	fibers					1297:1302	the cellulose fibers	1283:1302	the cellulose fibers	1283:1302	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	6	7	theme	powder	1373:1378	arg1	photocatalyst					1394:1406	powder semiconductor photocatalyst	1373:1406	powder semiconductor photocatalyst in practical applications	1373:1432	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	4	8	theme	control	984:990	arg1	papers					992:997	other control papers	978:997	other control papers	978:997	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	1	9	theme	scheme	219:224	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	10	theme	structure	610:618	arg1	regulation					580:589	effective regulation	570:589	effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction	570:719	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	7	11	theme	cellulose	1515:1523	arg1	fibers					1525:1530	cellulose fibers	1515:1530	cellulose fibers	1515:1530	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	6	12	theme	Loading	1257:1263	arg1	heterojunction					1265:1278	Loading heterojunction	1257:1278	Loading heterojunction on the cellulose fibers	1257:1302	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	3	13	theme	valence	818:824	arg1	band					826:829	the valence band	814:829	the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors	814:961	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	0	14	theme	recyclable	122:131	arg1	paper					148:152	high-performance and recyclable photocatalytic paper	101:152	high-performance and recyclable photocatalytic paper	101:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	15	theme	electron	241:248	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	16	theme	energy	598:603	arg1	structure					610:618	energy band structure	598:618	energy band structure	598:618	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	2	17	theme	Fermi	624:628	arg1	level					630:634	Fermi level	624:634	Fermi level	624:634	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	4	18	theme	O-vacancy	1000:1008	arg1	paper					1024:1028	O-vacancy Bi2WO6/SrTiO3 paper	1000:1028	O-vacancy Bi2WO6/SrTiO3 paper	1000:1028	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	7	19	theme	scheme	1491:1496	arg1	heterogeneity					1498:1510	Z scheme heterogeneity	1489:1510	Z scheme heterogeneity on cellulose fibers	1489:1530	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	6	20	theme	poor	1326:1329	arg1	reusability					1331:1341	poor reusability	1326:1341	poor reusability	1326:1341	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	3	21	theme	redox	928:932	arg1	capability					934:943	the redox capability	924:943	the redox capability of semiconductors	924:961	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	3	22	theme	separation	861:870	arg1	efficiency					872:881	the separation efficiency	857:881	the separation efficiency of photogenerated carriers	857:908	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	0	23	theme	Bi2WO6/SrTiO3	56:68	arg1	hybrid					70:75	direct Z scheme Bi2WO6/SrTiO3 hybrid	40:75	direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper	40:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	5	24	theme	good	1220:1223	arg1	stability					1246:1254	good photocatalytic cycle stability	1220:1254	good photocatalytic cycle stability	1220:1254	The O-vacancy Bi2WO6/SrTiO3 paper also showed good photocatalytic cycle stability.					
35487110	1	25	theme	O-vacancy	159:167	arg1	photocatalyst					198:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst	155:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism	155:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	26	theme	visible	543:549	arg1	light					551:555	visible light	543:555	visible light	543:555	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	5	27	theme	cycle	1240:1244	arg1	stability					1246:1254	good photocatalytic cycle stability	1220:1254	good photocatalytic cycle stability	1220:1254	The O-vacancy Bi2WO6/SrTiO3 paper also showed good photocatalytic cycle stability.					
35487110	1	28	theme	heterojunction	183:196	arg1	photocatalyst					198:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst	155:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism	155:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	4	29	theme	photocatalytic	1049:1062	arg1	performance					1064:1074	the best photocatalytic performance	1040:1074	the best photocatalytic performance	1040:1074	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	3	30	theme	carriers	901:908	arg1	efficiency					872:881	the separation efficiency	857:881	the separation efficiency of photogenerated carriers	857:908	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	5	31	theme	Bi2WO6/SrTiO3	1188:1200	arg1	paper					1202:1206	The O-vacancy Bi2WO6/SrTiO3 paper	1174:1206	The O-vacancy Bi2WO6/SrTiO3 paper	1174:1206	The O-vacancy Bi2WO6/SrTiO3 paper also showed good photocatalytic cycle stability.					
35487110	2	32	theme	effective	570:578	arg1	regulation					580:589	effective regulation	570:589	effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction	570:719	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	2	33	theme	O	458:458	arg1	vacancies					460:468	O vacancies	458:468	O vacancies	458:468	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	0	34	theme	high-performance	101:116	arg1	paper					148:152	high-performance and recyclable photocatalytic paper	101:152	high-performance and recyclable photocatalytic paper	101:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	4	35	theme	rhodamine	1106:1114	arg1	B					1116:1116	rhodamine B	1106:1116	rhodamine B	1106:1116	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	1	36	theme	visible	315:321	arg1	paper					365:369	a visible light-responsive photocatalytic composite paper	313:369	a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water	313:435	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	7	37	theme	novel	1457:1461	arg1	strategy					1463:1470	a novel strategy	1455:1470	a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability	1455:1612	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	0	38	theme	oxygen	16:21	arg1	vacancy					23:29	oxygen vacancy	16:29	oxygen vacancy	16:29	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	39	theme	photocatalytic	340:353	arg1	paper					365:369	a visible light-responsive photocatalytic composite paper	313:369	a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water	313:435	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	7	40	theme	high	1564:1567	arg1	activity					1584:1591	high photocatalytic activity	1564:1591	high photocatalytic activity	1564:1591	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	2	41	theme	Bi2WO6	532:537	arg1	rate					524:527	the utilization rate	508:527	the utilization rate of Bi2WO6 for visible light	508:555	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	3	42	theme	light-excited	726:738	arg1	electrons					740:748	The light-excited electrons	722:748	The light-excited electrons in the conduction band of O-vacancy Bi2WO6	722:791	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	6	43	from	heterojunction	1265:1278	arg1	fibers					1297:1302	the cellulose fibers	1283:1302	the cellulose fibers	1283:1302	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	2	44	from	introduction	442:453	arg1	Bi2WO6					473:478	Bi2WO6	473:478	Bi2WO6	473:478	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	0	45	theme	Z	47:47	arg1	hybrid					70:75	direct Z scheme Bi2WO6/SrTiO3 hybrid	40:75	direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper	40:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	46	theme	efficient	375:383	arg1	degradation					400:410	efficient and recyclable degradation	375:410	efficient and recyclable degradation of organic dyes	375:426	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	1	47	theme	recyclable	389:398	arg1	degradation					400:410	efficient and recyclable degradation	375:410	efficient and recyclable degradation of organic dyes	375:426	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	3	48	theme	conduction	757:766	arg1	band					768:771	the conduction band	753:771	the conduction band of O-vacancy Bi2WO6	753:791	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	3	49	from	electrons	740:748	arg1	band					768:771	the conduction band	753:771	the conduction band of O-vacancy Bi2WO6	753:791	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	3	50	theme	Bi2WO6	786:791	arg1	band					768:771	the conduction band	753:771	the conduction band of O-vacancy Bi2WO6	753:791	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	2	51	theme	Bi2WO6/SrTiO3	655:667	arg1	heterojunction					677:690	Bi2WO6/SrTiO3 type-II heterojunction	655:690	Bi2WO6/SrTiO3 type-II heterojunction	655:690	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	4	52	theme	lamp	1156:1159	arg1	irradiation					1161:1171	Xe lamp irradiation	1153:1171	Xe lamp irradiation	1153:1171	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	1	53	from	paper	365:369	arg1	water					431:435	water	431:435	water	431:435	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	6	54	theme	semiconductor	1380:1392	arg1	photocatalyst					1394:1406	powder semiconductor photocatalyst	1373:1406	powder semiconductor photocatalyst in practical applications	1373:1432	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	7	55	theme	good	1597:1600	arg1	reusability					1602:1612	good reusability	1597:1612	good reusability	1597:1612	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	2	56	theme	Z	697:697	arg1	heterojunction					706:719	Z scheme heterojunction	697:719	Z scheme heterojunction	697:719	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	7	57	theme	photocatalytic	1569:1582	arg1	activity					1584:1591	high photocatalytic activity	1564:1591	high photocatalytic activity	1564:1591	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	4	58	theme	degradation	1085:1095	arg1	rate					1097:1100	its degradation rate	1081:1100	its degradation rate for rhodamine B	1081:1116	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	1	59	theme	Z	217:217	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	3	60	theme	SrTiO3	834:839	arg1	band					826:829	the valence band	814:829	the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors	814:961	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	0	61	theme	photocatalytic	133:146	arg1	paper					148:152	high-performance and recyclable photocatalytic paper	101:152	high-performance and recyclable photocatalytic paper	101:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	62	theme	photogenerated	226:239	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	63	theme	band	605:608	arg1	structure					610:618	energy band structure	598:618	energy band structure	598:618	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	7	64	theme	composite	1543:1551	arg1	paper					1553:1557	composite paper	1543:1557	composite paper	1543:1557	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	1	65	theme	transfer	250:257	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	0	66	from	hybrid	70:75	arg1	fibers					90:95	cellulose fibers	80:95	cellulose fibers	80:95	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	6	67	theme	difficult	1347:1355	arg1	problem					1315:1321	the problem	1311:1321	the problem of poor reusability and difficult in recovery	1311:1367	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	5	68	theme	O-vacancy	1178:1186	arg1	paper					1202:1206	The O-vacancy Bi2WO6/SrTiO3 paper	1174:1206	The O-vacancy Bi2WO6/SrTiO3 paper	1174:1206	The O-vacancy Bi2WO6/SrTiO3 paper also showed good photocatalytic cycle stability.					
35487110	2	69	theme	level	630:634	arg1	regulation					580:589	effective regulation	570:589	effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction	570:719	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	6	70	theme	reusability	1331:1341	arg1	problem					1315:1321	the problem	1311:1321	the problem of poor reusability and difficult in recovery	1311:1367	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	3	71	theme	semiconductors	948:961	arg1	capability					934:943	the redox capability	924:943	the redox capability of semiconductors	924:961	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	3	72	theme	photogenerated	886:899	arg1	carriers					901:908	photogenerated carriers	886:908	photogenerated carriers	886:908	The light-excited electrons in the conduction band of O-vacancy Bi2WO6 directly migrated to the valence band of SrTiO3, which improved the separation efficiency of photogenerated carriers and maximized the redox capability of semiconductors.					
35487110	7	73	theme	Z	1489:1489	arg1	heterogeneity					1498:1510	Z scheme heterogeneity	1489:1510	Z scheme heterogeneity on cellulose fibers	1489:1530	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	6	74	from	problem	1315:1321	arg1	recovery					1360:1367	recovery	1360:1367	recovery	1360:1367	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	0	75	theme	cellulose	80:88	arg1	fibers					90:95	cellulose fibers	80:95	cellulose fibers	80:95	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	5	76	theme	photocatalytic	1225:1238	arg1	stability					1246:1254	good photocatalytic cycle stability	1220:1254	good photocatalytic cycle stability	1220:1254	The O-vacancy Bi2WO6/SrTiO3 paper also showed good photocatalytic cycle stability.					
35487110	1	77	theme	Bi2WO6/SrTiO3	169:181	arg1	photocatalyst					198:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst	155:210	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism	155:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	1	78	theme	dyes	423:426	arg1	degradation					400:410	efficient and recyclable degradation	375:410	efficient and recyclable degradation of organic dyes	375:426	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	4	79	theme	Bi2WO6/SrTiO3	1010:1022	arg1	paper					1024:1028	O-vacancy Bi2WO6/SrTiO3 paper	1000:1028	O-vacancy Bi2WO6/SrTiO3 paper	1000:1028	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	1	80	theme	organic	415:421	arg1	dyes					423:426	organic dyes	415:426	organic dyes	415:426	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	7	81	from	heterogeneity	1498:1510	arg1	fibers					1525:1530	cellulose fibers	1515:1530	cellulose fibers	1515:1530	This study provides a novel strategy for constructing Z scheme heterogeneity on cellulose fibers to prepare composite paper with high photocatalytic activity and good reusability.					
35487110	0	82	theme	vacancy	23:29	arg1	Construction					0:11	Construction	0:11	Construction of oxygen vacancy	0:29	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	83	theme	light-responsive	323:338	arg1	paper					365:369	a visible light-responsive photocatalytic composite paper	313:369	a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water	313:435	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	84	theme	alkali	483:488	arg1	etching					490:496	alkali etching	483:496	alkali etching	483:496	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	0	85	theme	direct	40:45	arg1	hybrid					70:75	direct Z scheme Bi2WO6/SrTiO3 hybrid	40:75	direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper	40:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	1	86	theme	composite	355:363	arg1	paper					365:369	a visible light-responsive photocatalytic composite paper	313:369	a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water	313:435	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	2	87	theme	vacancies	460:468	arg1	introduction					442:453	The introduction	438:453	The introduction of O vacancies in Bi2WO6 by alkali etching	438:496	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	0	88	theme	scheme	49:54	arg1	hybrid					70:75	direct Z scheme Bi2WO6/SrTiO3 hybrid	40:75	direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper	40:152	Construction of oxygen vacancy mediated direct Z scheme Bi2WO6/SrTiO3 hybrid on cellulose fibers for high-performance and recyclable photocatalytic paper.					
35487110	2	89	theme	utilization	512:522	arg1	rate					524:527	the utilization rate	508:527	the utilization rate of Bi2WO6 for visible light	508:555	The introduction of O vacancies in Bi2WO6 by alkali etching increased the utilization rate of Bi2WO6 for visible light and achieved effective regulation of the energy band structure and Fermi level, which transformed Bi2WO6/SrTiO3 type-II heterojunction into Z scheme heterojunction.					
35487110	1	90	with	photocatalyst	198:210	arg1	mechanism					259:267	Z scheme photogenerated electron transfer mechanism	217:267	Z scheme photogenerated electron transfer mechanism	217:267	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
35487110	4	91	theme	irradiation	1161:1171	arg1	100 min					1142:1148	100 min	1142:1148	100 min of Xe lamp irradiation	1142:1171	Compared with other control papers, O-vacancy Bi2WO6/SrTiO3 paper exhibited the best photocatalytic performance, and its degradation rate for rhodamine B could reach 71.1% under 100 min of Xe lamp irradiation.					
35487110	6	92	from	photocatalyst	1394:1406	arg1	applications					1421:1432	practical applications	1411:1432	practical applications	1411:1432	Loading heterojunction on the cellulose fibers solved the problem of poor reusability and difficult in recovery for powder semiconductor photocatalyst in practical applications.					
35487110	1	93	theme	cellulose	283:291	arg1	fibers					293:298	cellulose fibers	283:298	cellulose fibers	283:298	The O-vacancy Bi2WO6/SrTiO3 heterojunction photocatalyst with Z scheme photogenerated electron transfer mechanism was loaded on cellulose fibers to construct a visible light-responsive photocatalytic composite paper for efficient and recyclable degradation of organic dyes in water.					
36254853	1	0	theme	biomedicine	157:167	arg1	field					148:152	the field	144:152	the field of biomedicine	144:167	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	7	1	theme	great	977:981	arg1	potential					983:991	great potential	977:991	great potential	977:991	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	4	2	theme	self-healing	632:643	arg1	properties					645:654	self-healing properties	632:654	self-healing properties	632:654	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	0	3	theme	Wound	80:84	arg1	Dressing					86:93	Wound Dressing	80:93	Wound Dressing	80:93	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	4	4	theme	PDA	564:566	arg1	component					569:577	polydopamine (PDA) component	550:577	polydopamine (PDA) component	550:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	6	5	theme	tissue	893:898	arg1	regeneration					900:911	skin tissue regeneration	888:911	skin tissue regeneration	888:911	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	7	6	contain	have	972:975	arg1	hydrogels					962:970	CS/PDA/PAM hydrogels	951:970	CS/PDA/PAM hydrogels	951:970	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	7	6	contain	have	972:975	arg2	potential					983:991	great potential	977:991	great potential	977:991	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	7	7	theme	CS/PDA/PAM	951:960	arg1	hydrogels					962:970	CS/PDA/PAM hydrogels	951:970	CS/PDA/PAM hydrogels	951:970	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	7	8	theme	dressings	1025:1033	arg1	application					1000:1010	the application	996:1010	the application of new wound dressings	996:1033	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	6	9	theme	skin	888:891	arg1	regeneration					900:911	skin tissue regeneration	888:911	skin tissue regeneration	888:911	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	2	10	theme	mechanical	288:297	arg1	properties					299:308	mechanical properties	288:308	mechanical properties	288:308	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	5	11	theme	CS/PDA/PAM	787:796	arg1	hydrogels					798:806	CS/PDA/PAM hydrogels	787:806	CS/PDA/PAM hydrogels	787:806	The introduction of chitosan (CS) not only greatly improves antibacterial ability, but also enhances the mechanical properties of CS/PDA/PAM hydrogels.					
36254853	5	12	theme	antibacterial	717:729	arg1	ability					731:737	antibacterial ability	717:737	antibacterial ability	717:737	The introduction of chitosan (CS) not only greatly improves antibacterial ability, but also enhances the mechanical properties of CS/PDA/PAM hydrogels.					
36254853	5	13	theme	hydrogels	798:806	arg1	properties					773:782	the mechanical properties	758:782	the mechanical properties of CS/PDA/PAM hydrogels	758:806	The introduction of chitosan (CS) not only greatly improves antibacterial ability, but also enhances the mechanical properties of CS/PDA/PAM hydrogels.					
36254853	2	14	theme	hydrogels	356:364	arg1	properties					329:338	antibacterial properties	315:338	antibacterial properties	315:338	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	2	14	theme	hydrogels	356:364	arg1	satisfactory					374:385	satisfactory	374:385	satisfactory	374:385	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	2	14	theme	hydrogels	356:364	arg1	adhesiveness					274:285	the adhesiveness	270:285	the adhesiveness	270:285	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	2	14	theme	hydrogels	356:364	arg1	properties					299:308	mechanical properties	288:308	mechanical properties	288:308	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	5	15	theme	chitosan	677:684	arg1	introduction					661:672	The introduction	657:672	The introduction of chitosan (CS)	657:689	The introduction of chitosan (CS) not only greatly improves antibacterial ability, but also enhances the mechanical properties of CS/PDA/PAM hydrogels.					
36254853	0	16	theme	Stretchable	45:55	arg1	Hydrogel					67:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel	0:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.	0:94	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	7	17	theme	wound	1019:1023	arg1	dressings					1025:1033	new wound dressings	1015:1033	new wound dressings	1015:1033	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	0	18	theme	Adhesive	16:23	arg1	Hydrogel					67:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel	0:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.	0:94	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	4	19	theme	catechol	532:539	arg1	group					541:545	The catechol group	528:545	The catechol group of polydopamine (PDA) component	528:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	4	19	theme	catechol	532:539	arg1	component					569:577	polydopamine (PDA) component	550:577	polydopamine (PDA) component	550:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	6	20	theme	CS/PDA/PAM	850:859	arg1	hydrogels					861:869	CS/PDA/PAM hydrogels	850:869	CS/PDA/PAM hydrogels	850:869	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	2	21	theme	antibacterial	315:327	arg1	properties					329:338	antibacterial properties	315:338	antibacterial properties	315:338	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	1	22	theme	similar	186:192	arg1	structure					194:202	their similar structure	180:202	their similar structure to extracellular matrix (ECM) and good biocompatibility	180:258	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	0	23	theme	Mussel-Inspired	0:14	arg1	Hydrogel					67:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel	0:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.	0:94	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	0	24	theme	Antibacterial	26:38	arg1	Hydrogel					67:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel	0:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.	0:94	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	1	25	from	attention	131:139	arg1	field					148:152	the field	144:152	the field of biomedicine	144:167	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	3	26	theme	nature-inspired	502:516	arg1	strategy					518:525	a nature-inspired strategy	500:525	a nature-inspired strategy	500:525	In this study, multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels are prepared through a nature-inspired strategy.					
36254853	1	27	theme	extracellular	207:219	arg1	ECM					229:231	ECM	229:231	ECM	229:231	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	1	27	theme	extracellular	207:219	arg1	matrix					221:226	extracellular matrix	207:226	extracellular matrix (ECM)	207:232	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	4	28	theme	tissue	612:617	arg1	adhesion					619:626	tissue adhesion	612:626	tissue adhesion	612:626	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	5	29	theme	mechanical	762:771	arg1	properties					773:782	the mechanical properties	758:782	the mechanical properties of CS/PDA/PAM hydrogels	758:806	The introduction of chitosan (CS) not only greatly improves antibacterial ability, but also enhances the mechanical properties of CS/PDA/PAM hydrogels.					
36254853	4	30	theme	component	569:577	arg1	group					541:545	The catechol group	528:545	The catechol group of polydopamine (PDA) component	528:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	4	30	theme	component	569:577	arg1	component					569:577	polydopamine (PDA) component	550:577	polydopamine (PDA) component	550:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	0	31	theme	Composite	57:65	arg1	Hydrogel					67:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel	0:74	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.	0:94	Mussel-Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing.					
36254853	6	32	theme	healing	820:826	arg1	experiments					828:838	Skin wound healing experiments	809:838	Skin wound healing experiments	809:838	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	1	33	theme	extensive	121:129	arg1	attention					131:139	extensive attention	121:139	extensive attention in the field of biomedicine	121:167	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
36254853	3	34	theme	chitosan/polydopamine/polyacrylamide	419:454	arg1	hydrogels					469:477	multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels	403:477	multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels	403:477	In this study, multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels are prepared through a nature-inspired strategy.					
36254853	4	35	theme	CS/PDA/PAM	586:595	arg1	hydrogels					597:605	CS/PDA/PAM hydrogels	586:605	CS/PDA/PAM hydrogels	586:605	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	6	36	theme	wound	925:929	arg1	healing					931:937	wound healing	925:937	wound healing	925:937	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	6	37	theme	wound	814:818	arg1	healing					820:826	Skin wound healing	809:826	Skin wound healing experiments	809:838	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	2	38	theme	conventional	343:354	arg1	hydrogels					356:364	conventional hydrogels	343:364	conventional hydrogels	343:364	However, the adhesiveness, mechanical properties, and antibacterial properties of conventional hydrogels are not satisfactory.					
36254853	7	39	theme	new	1015:1017	arg1	dressings					1025:1033	new wound dressings	1015:1033	new wound dressings	1015:1033	Therefore, CS/PDA/PAM hydrogels have great potential in the application of new wound dressings.					
36254853	6	40	theme	Skin	809:812	arg1	healing					820:826	Skin wound healing	809:826	Skin wound healing experiments	809:838	Skin wound healing experiments show that CS/PDA/PAM hydrogels could accelerate skin tissue regeneration and promote wound healing.					
36254853	3	41	theme	multifunctional	403:417	arg1	chitosan/polydopamine/polyacrylamide					419:454	multifunctional chitosan/polydopamine/polyacrylamide	403:454	multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels	403:477	In this study, multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels are prepared through a nature-inspired strategy.					
36254853	3	41	theme	multifunctional	403:417	arg1	CS/PDA/PAM					457:466	CS/PDA/PAM	457:466	CS/PDA/PAM	457:466	In this study, multifunctional chitosan/polydopamine/polyacrylamide (CS/PDA/PAM) hydrogels are prepared through a nature-inspired strategy.					
36254853	4	42	theme	polydopamine	550:561	arg1	component					569:577	polydopamine (PDA) component	550:577	polydopamine (PDA) component	550:577	The catechol group of polydopamine (PDA) component endows CS/PDA/PAM hydrogels with tissue adhesion and self-healing properties.					
36254853	1	43	theme	good	238:241	arg1	biocompatibility					243:258	good biocompatibility	238:258	good biocompatibility	238:258	Hydrogels have attracted extensive attention in the field of biomedicine because of their similar structure to extracellular matrix (ECM) and good biocompatibility.					
37388683	0	0	theme	Spike	89:93	arg1	Protein					95:101	the Viral Spike Protein	79:101	the Viral Spike Protein	79:101	Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.					
37388683	8	1	from	contrast	1181:1188	arg1	ineffective					1245:1255	ineffective	1245:1255	ineffective	1245:1255	In contrast, natural tetrameric DC-SIGN and its G13 conjugate were ineffective.					
37388683	7	2	theme	Delta	1118:1122	arg1	proteins					1089:1096	the S proteins	1083:1096	the S proteins of Wuhan Hu-1, B.1	1083:1115	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	2	theme	Delta	1118:1122	arg1	variant					1124:1130	Delta variant	1118:1130	Delta variant	1118:1130	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	8	3	from	ineffective	1245:1255	arg1	contrast					1181:1188	contrast	1181:1188	contrast	1181:1188	In contrast, natural tetrameric DC-SIGN and its G13 conjugate were ineffective.					
37388683	2	4	theme	robust	354:359	arg1	target					361:366	a potential robust target	342:366	a potential robust target for developing antivirals	342:392	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	9	5	theme	SARS-CoV-2	1304:1313	arg1	B.1					1315:1317	authentic SARS-CoV-2 B.1	1294:1317	authentic SARS-CoV-2 B.1	1294:1317	Further, G13-CRD potently inhibited authentic SARS-CoV-2 B.1 and BA.1, with <10 pM and <10 nM EC50, respectively.					
37388683	4	6	theme	recognition	617:627	arg1	domains					629:635	flexibly linked carbohydrate recognition domains	588:635	flexibly linked carbohydrate recognition domains (CRDs)	588:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	6	theme	recognition	617:627	arg1	CRDs					638:641	CRDs	638:641	CRDs	638:641	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	0	7	theme	Viral	83:87	arg1	Protein					95:101	the Viral Spike Protein	79:101	the Viral Spike Protein	79:101	Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.					
37388683	10	8	theme	polyvalent	1414:1423	arg1	nano-lectin					1425:1435	the 1st polyvalent nano-lectin	1406:1435	the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy	1406:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	10	8	theme	polyvalent	1414:1423	arg1	G13-CRD					1395:1401	G13-CRD	1395:1401	G13-CRD	1395:1401	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	2	9	theme	potential	344:352	arg1	target					361:366	a potential robust target	342:366	a potential robust target for developing antivirals	342:392	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	2	10	from	rare	321:324	arg1	contrast					242:249	contrast	242:249	contrast	242:249	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	4	11	theme	carbohydrate	604:615	arg1	domains					629:635	flexibly linked carbohydrate recognition domains	588:635	flexibly linked carbohydrate recognition domains (CRDs)	588:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	11	theme	carbohydrate	604:615	arg1	CRDs					638:641	CRDs	638:641	CRDs	638:641	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	9	12	theme	authentic	1294:1302	arg1	B.1					1315:1317	authentic SARS-CoV-2 B.1	1294:1317	authentic SARS-CoV-2 B.1	1294:1317	Further, G13-CRD potently inhibited authentic SARS-CoV-2 B.1 and BA.1, with <10 pM and <10 nM EC50, respectively.					
37388683	7	13	theme	B.1	1113:1115	arg1	BA.1					1155:1158	Omicron subvariant BA.1	1136:1158	Omicron subvariant BA.1	1136:1158	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	13	theme	B.1	1113:1115	arg1	variant					1124:1130	Delta variant	1118:1130	Delta variant	1118:1130	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	13	theme	B.1	1113:1115	arg1	proteins					1089:1096	the S proteins	1083:1096	the S proteins of Wuhan Hu-1, B.1	1083:1115	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	2	14	theme	SARS-CoV-2	292:301	arg1	variants					303:310	SARS-CoV-2 variants	292:310	SARS-CoV-2 variants	292:310	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	0	15	from	Glycans	68:74	arg1	Protein					95:101	the Viral Spike Protein	79:101	the Viral Spike Protein	79:101	Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.					
37388683	3	16	theme	monovalent	499:508	arg1	interactions					525:536	intrinsically weak monovalent protein-glycan interactions	480:536	intrinsically weak monovalent protein-glycan interactions	480:536	However, this target has not been adequately exploited for SARS-CoV-2, mostly due to intrinsically weak monovalent protein-glycan interactions.					
37388683	6	17	theme	quantum	997:1003	arg1	dots					1005:1008	target glycan-coated quantum dots	976:1008	target glycan-coated quantum dots with sub-nM Kd	976:1023	G13-CRD bound strongly and specifically to target glycan-coated quantum dots with sub-nM Kd.					
37388683	2	18	gly	glycosylation	265:277	arg2	sites					279:283	glycosylation sites	265:283	glycosylation sites across SARS-CoV-2 variants	265:310	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	4	19	theme	potent	746:751	arg1	activity					763:770	potent antiviral activity	746:770	potent antiviral activity	746:770	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	1	20	dep	spike	117:121	arg1	S					124:124	S	124:124	S	124:124	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	8	21	theme	G13	1226:1228	arg1	conjugate					1230:1238	its G13 conjugate	1222:1238	its G13 conjugate	1222:1238	In contrast, natural tetrameric DC-SIGN and its G13 conjugate were ineffective.					
37388683	5	22	theme	dendritic	817:825	arg1	lectin					832:837	a dendritic cell lectin	815:837	a dendritic cell lectin known to bind to diverse viruses	815:870	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	5	22	theme	dendritic	817:825	arg1	DC-SIGN					806:812	DC-SIGN	806:812	DC-SIGN	806:812	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	7	23	theme	subvariant	1144:1153	arg1	BA.1					1155:1158	Omicron subvariant BA.1	1136:1158	Omicron subvariant BA.1	1136:1158	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	23	theme	subvariant	1144:1153	arg1	proteins					1089:1096	the S proteins	1083:1096	the S proteins of Wuhan Hu-1, B.1	1083:1115	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	2	24	theme	glycosylation	265:277	arg1	sites					279:283	glycosylation sites	265:283	glycosylation sites across SARS-CoV-2 variants	265:310	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	10	25	with	nano-lectin	1425:1435	arg1	activity					1448:1455	broad activity	1442:1455	broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy	1442:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	9	26	theme	nM	1349:1350	arg1	EC50					1352:1355	<10 pM and <10 nM EC50	1334:1355	<10 pM and <10 nM EC50	1334:1355	Further, G13-CRD potently inhibited authentic SARS-CoV-2 B.1 and BA.1, with <10 pM and <10 nM EC50, respectively.					
37388683	5	27	theme	cell	827:830	arg1	lectin					832:837	a dendritic cell lectin	815:837	a dendritic cell lectin known to bind to diverse viruses	815:870	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	5	27	theme	cell	827:830	arg1	DC-SIGN					806:812	DC-SIGN	806:812	DC-SIGN	806:812	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	10	28	theme	novel	1522:1526	arg1	approach					1528:1535	a novel approach	1520:1535	a novel approach to antiviral therapy	1520:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	10	29	theme	broad	1442:1446	arg1	activity					1448:1455	broad activity	1442:1455	broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy	1442:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	5	30	dep	nanoparticles	902:914	arg1	named					917:921	named	917:921	named G13-CRD	917:929	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	7	31	theme	nM	1169:1170	arg1	EC50					1172:1175	low nM EC50	1165:1175	low nM EC50	1165:1175	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	4	32	theme	S	706:706	arg1	glycans					716:722	S protein glycans	706:722	S protein glycans	706:722	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	0	33	theme	Polyvalent	0:9	arg1	Nano-Lectin					11:21	Polyvalent Nano-Lectin	0:21	Polyvalent Nano-Lectin	0:21	Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.					
37388683	6	34	theme	glycan-coated	983:995	arg1	dots					1005:1008	target glycan-coated quantum dots	976:1008	target glycan-coated quantum dots with sub-nM Kd	976:1023	G13-CRD bound strongly and specifically to target glycan-coated quantum dots with sub-nM Kd.					
37388683	1	35	theme	antibody	179:186	arg1	responses					188:196	antibody responses	179:196	antibody responses induced by infection and/or vaccination	179:236	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	6	36	theme	target	976:981	arg1	dots					1005:1008	target glycan-coated quantum dots	976:1008	target glycan-coated quantum dots with sub-nM Kd	976:1023	G13-CRD bound strongly and specifically to target glycan-coated quantum dots with sub-nM Kd.					
37388683	7	37	theme	S	1087:1087	arg1	BA.1					1155:1158	Omicron subvariant BA.1	1136:1158	Omicron subvariant BA.1	1136:1158	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	37	theme	S	1087:1087	arg1	variant					1124:1130	Delta variant	1118:1130	Delta variant	1118:1130	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	37	theme	S	1087:1087	arg1	proteins					1089:1096	the S proteins	1083:1096	the S proteins of Wuhan Hu-1, B.1	1083:1115	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	8	38	theme	tetrameric	1199:1208	arg1	DC-SIGN					1210:1216	natural tetrameric DC-SIGN	1191:1216	natural tetrameric DC-SIGN	1191:1216	In contrast, natural tetrameric DC-SIGN and its G13 conjugate were ineffective.					
37388683	2	39	from	contrast	242:249	arg1	rare					321:324	rare	321:324	rare	321:324	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	4	40	theme	relative	661:668	arg1	positions					670:678	their relative positions	655:678	their relative positions	655:678	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	7	41	theme	low	1165:1167	arg1	nM					1169:1170	low nM	1165:1170	low nM EC50	1165:1175	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	4	42	theme	linked	597:602	arg1	domains					629:635	flexibly linked carbohydrate recognition domains	588:635	flexibly linked carbohydrate recognition domains (CRDs)	588:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	42	theme	linked	597:602	arg1	CRDs					638:641	CRDs	638:641	CRDs	638:641	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	1	43	theme	SARS-CoV-2	150:159	arg1	variants					161:168	SARS-CoV-2 variants	150:168	SARS-CoV-2 variants	150:168	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	5	44	theme	nm	894:895	arg1	nanoparticles					902:914	13 nm gold nanoparticles	891:914	13 nm gold nanoparticles (named G13-CRD)	891:930	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	5	45	theme	DC-SIGN	806:812	arg1	CRDs					798:801	the CRDs	794:801	the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses,	794:871	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	9	46	theme	pM	1338:1339	arg1	EC50					1352:1355	<10 pM and <10 nM EC50	1334:1355	<10 pM and <10 nM EC50	1334:1355	Further, G13-CRD potently inhibited authentic SARS-CoV-2 B.1 and BA.1, with <10 pM and <10 nM EC50, respectively.					
37388683	2	47	from	mutations	252:260	arg1	sites					279:283	glycosylation sites	265:283	glycosylation sites across SARS-CoV-2 variants	265:310	In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing antivirals.					
37388683	5	48	theme	diverse	856:862	arg1	viruses					864:870	diverse viruses	856:870	diverse viruses	856:870	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	8	49	theme	natural	1191:1197	arg1	DC-SIGN					1210:1216	natural tetrameric DC-SIGN	1191:1216	natural tetrameric DC-SIGN	1191:1216	In contrast, natural tetrameric DC-SIGN and its G13 conjugate were ineffective.					
37388683	10	50	theme	SARS-CoV-2	1465:1474	arg1	variants					1476:1483	SARS-CoV-2 variants	1465:1483	SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy	1465:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	10	51	theme	1st	1410:1412	arg1	nano-lectin					1425:1435	the 1st polyvalent nano-lectin	1406:1435	the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy	1406:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	10	51	theme	1st	1410:1412	arg1	G13-CRD					1395:1401	G13-CRD	1395:1401	G13-CRD	1395:1401	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	1	52	theme	spike	117:121	arg1	epitopes					135:142	spike (S) protein epitopes	117:142	spike (S) protein epitopes	117:142	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	0	53	theme	Targeting	58:66	arg1	Glycans					68:74	Targeting Glycans	58:74	Targeting Glycans on the Viral Spike Protein	58:101	Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.					
37388683	4	54	theme	polyvalent	559:568	arg1	nano-lectins					570:581	polyvalent nano-lectins	559:581	polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs)	559:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	3	55	theme	protein-glycan	510:523	arg1	interactions					525:536	intrinsically weak monovalent protein-glycan interactions	480:536	intrinsically weak monovalent protein-glycan interactions	480:536	However, this target has not been adequately exploited for SARS-CoV-2, mostly due to intrinsically weak monovalent protein-glycan interactions.					
37388683	3	56	theme	weak	494:497	arg1	interactions					525:536	intrinsically weak monovalent protein-glycan interactions	480:536	intrinsically weak monovalent protein-glycan interactions	480:536	However, this target has not been adequately exploited for SARS-CoV-2, mostly due to intrinsically weak monovalent protein-glycan interactions.					
37388683	1	57	from	Mutations	104:112	arg1	epitopes					135:142	spike (S) protein epitopes	117:142	spike (S) protein epitopes	117:142	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	7	58	theme	Omicron	1136:1142	arg1	BA.1					1155:1158	Omicron subvariant BA.1	1136:1158	Omicron subvariant BA.1	1136:1158	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	7	58	theme	Omicron	1136:1142	arg1	proteins					1089:1096	the S proteins	1083:1096	the S proteins of Wuhan Hu-1, B.1	1083:1115	Moreover, G13-CRD neutralized particles pseudotyped with the S proteins of Wuhan Hu-1, B.1, Delta variant and Omicron subvariant BA.1 with low nM EC50.					
37388683	6	59	with	dots	1005:1008	arg1	Kd					1022:1023	sub-nM Kd	1015:1023	sub-nM Kd	1015:1023	G13-CRD bound strongly and specifically to target glycan-coated quantum dots with sub-nM Kd.					
37388683	5	60	theme	13	891:892	arg1	nm					894:895	nm	894:895	nm	894:895	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	4	61	with	nano-lectins	570:581	arg1	domains					629:635	flexibly linked carbohydrate recognition domains	588:635	flexibly linked carbohydrate recognition domains (CRDs)	588:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	61	with	nano-lectins	570:581	arg1	CRDs					638:641	CRDs	638:641	CRDs	638:641	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	62	theme	antiviral	753:761	arg1	activity					763:770	potent antiviral activity	746:770	potent antiviral activity	746:770	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	10	63	theme	antiviral	1540:1548	arg1	therapy					1550:1556	antiviral therapy	1540:1556	antiviral therapy	1540:1556	These results identify G13-CRD as the 1st polyvalent nano-lectin with broad activity against SARS-CoV-2 variants that merits further exploration as a novel approach to antiviral therapy.					
37388683	5	64	theme	gold	897:900	arg1	nanoparticles					902:914	13 nm gold nanoparticles	891:914	13 nm gold nanoparticles (named G13-CRD)	891:930	Herein, we displayed the CRDs of DC-SIGN, a dendritic cell lectin known to bind to diverse viruses, polyvalently onto 13 nm gold nanoparticles (named G13-CRD).					
37388683	1	65	theme	protein	127:133	arg1	epitopes					135:142	spike (S) protein epitopes	117:142	spike (S) protein epitopes	117:142	Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination.					
37388683	4	66	link	linked	597:602	arg1	domains					629:635	flexibly linked carbohydrate recognition domains	588:635	flexibly linked carbohydrate recognition domains (CRDs)	588:642	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	66	link	linked	597:602	arg1	CRDs					638:641	CRDs	638:641	CRDs	638:641	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
37388683	4	67	theme	protein	708:714	arg1	glycans					716:722	S protein glycans	706:722	S protein glycans	706:722	We hypothesize that polyvalent nano-lectins with flexibly linked carbohydrate recognition domains (CRDs) can adjust their relative positions and bind multivalently to S protein glycans, potentially exerting potent antiviral activity.					
35839947	1	0	from	effects	175:181	arg1	function					299:306	non-specific immune function	279:306	non-specific immune function	279:306	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	0	from	effects	175:181	arg1	performance					245:255	growth performance	238:255	growth performance	238:255	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	0	from	effects	175:181	arg1	composition					263:273	body composition	258:273	body composition	258:273	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	6	1	theme	chitosan	1307:1314	arg1	chitosan					1307:1314	chitosan	1307:1314	chitosan (8.95 g/kg)	1307:1326	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	6	1	theme	chitosan	1307:1314	arg1	amount					1297:1302	an appropriate amount	1282:1302	an appropriate amount of chitosan (8.95 g/kg)	1282:1326	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	6	1	theme	chitosan	1307:1314	arg1	8.95 g/kg					1317:1325	8.95 g/kg	1317:1325	8.95 g/kg	1317:1325	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	0	2	theme	nonspecific	72:82	arg1	immunity					84:91	nonspecific immunity	72:91	nonspecific immunity	72:91	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	3	theme	body	629:632	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	3	theme	body	629:632	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	1	4	theme	body	258:261	arg1	composition					263:273	body composition	258:273	body composition	258:273	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	5	theme	juvenile	96:103	arg1	fulvidraco					134:143	Pelteobagrus fulvidraco	121:143	Pelteobagrus fulvidraco	121:143	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	5	theme	juvenile	96:103	arg1	catfish					112:118	juvenile yellow catfish	96:118	juvenile yellow catfish (Pelteobagrus fulvidraco)	96:144	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	6	theme	protein	634:640	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	6	theme	protein	634:640	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	6	7	theme	growth	1388:1393	arg1	performance					1395:1405	its growth performance	1384:1405	its growth performance	1384:1405	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	3	8	theme	resistance	770:779	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	8	theme	resistance	770:779	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	9	theme	dismutase	668:676	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	9	theme	dismutase	668:676	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	6	10	theme	non-specific	1452:1463	arg1	immunity					1465:1472	its non-specific immunity	1448:1472	its non-specific immunity	1448:1472	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	0	11	theme	catfish	112:118	arg1	performance					38:48	growth performance	31:48	growth performance	31:48	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	11	theme	catfish	112:118	arg1	composition					56:66	body composition	51:66	body composition	51:66	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	11	theme	catfish	112:118	arg1	immunity					84:91	nonspecific immunity	72:91	nonspecific immunity	72:91	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	4	12	theme	feed	1094:1097	arg1	efficiency					1099:1108	feed efficiency	1094:1108	feed efficiency	1094:1108	No significant differences in feed efficiency among all groups (P > 0.05) were observed.					
35839947	5	13	theme	dietary	1173:1179	arg1	chitosan					1181:1188	dietary chitosan	1173:1188	dietary chitosan required for the maximum growth of juvenile yellow catfish	1173:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	0	14	theme	yellow	105:110	arg1	fulvidraco					134:143	Pelteobagrus fulvidraco	121:143	Pelteobagrus fulvidraco	121:143	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	14	theme	yellow	105:110	arg1	catfish					112:118	juvenile yellow catfish	96:118	juvenile yellow catfish (Pelteobagrus fulvidraco)	96:144	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	15	theme	serum	651:655	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	15	theme	serum	651:655	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	4	16	from	differences	1079:1089	arg1	efficiency					1099:1108	feed efficiency	1094:1108	feed efficiency	1094:1108	No significant differences in feed efficiency among all groups (P > 0.05) were observed.					
35839947	5	17	theme	chitosan	1181:1188	arg1	dose					1165:1168	The optimum dose	1153:1168	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish	1153:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	5	17	theme	chitosan	1181:1188	arg1	8.95 g/kg					1253:1261	8.95 g/kg	1253:1261	8.95 g/kg	1253:1261	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	2	18	theme	basal	488:492	arg1	feed					494:497	the basal feed	484:497	the basal feed	484:497	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	6	19	theme	appropriate	1285:1295	arg1	chitosan					1307:1314	chitosan	1307:1314	chitosan (8.95 g/kg)	1307:1326	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	6	19	theme	appropriate	1285:1295	arg1	amount					1297:1302	an appropriate amount	1282:1302	an appropriate amount of chitosan (8.95 g/kg)	1282:1326	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	6	19	theme	appropriate	1285:1295	arg1	8.95 g/kg					1317:1325	8.95 g/kg	1317:1325	8.95 g/kg	1317:1325	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	3	20	theme	superoxide	657:666	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	20	theme	superoxide	657:666	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	0	21	theme	Dietary	0:6	arg1	chitosan					8:15	Dietary chitosan	0:15	Dietary chitosan	0:15	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	22	theme	non-specific	279:290	arg1	function					299:306	non-specific immune function	279:306	non-specific immune function	279:306	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	4	23	theme	significant	1067:1077	arg1	differences					1079:1089	No significant differences	1064:1089	No significant differences in feed efficiency among all groups (P > 0.05)	1064:1136	No significant differences in feed efficiency among all groups (P > 0.05) were observed.					
35839947	6	24	theme	catfish	1350:1356	arg1	feed					1335:1338	the feed	1331:1338	the feed of yellow catfish	1331:1356	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	1	25	theme	feeding	186:192	arg1	concentrations					204:217	feeding different concentrations	186:217	feeding different concentrations of chitosan	186:229	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	26	theme	immune	292:297	arg1	function					299:306	non-specific immune function	279:306	non-specific immune function	279:306	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	27	theme	Pelteobagrus	121:132	arg1	fulvidraco					134:143	Pelteobagrus fulvidraco	121:143	Pelteobagrus fulvidraco	121:143	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	27	theme	Pelteobagrus	121:132	arg1	catfish					112:118	juvenile yellow catfish	96:118	juvenile yellow catfish (Pelteobagrus fulvidraco)	96:144	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	6	28	theme	yellow	1343:1348	arg1	catfish					1350:1356	yellow catfish	1343:1356	yellow catfish	1343:1356	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	1	29	theme	different	194:202	arg1	concentrations					204:217	feeding different concentrations	186:217	feeding different concentrations of chitosan	186:229	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	2	30	theme	control	435:441	arg1	chitosan					472:479	chitosan	472:479	chitosan	472:479	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	2	30	theme	control	435:441	arg1	0					432:432	0	432:432	0	432:432	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	2	30	theme	control	435:441	arg1	group					443:447	control group	435:447	control group	435:447	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	2	31	theme	juvenile	510:517	arg1	catfish					526:532	juvenile yellow catfish	510:532	juvenile yellow catfish for 8 weeks	510:544	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	3	32	theme	growth	601:606	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	32	theme	growth	601:606	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	5	33	theme	optimum	1157:1163	arg1	dose					1165:1168	The optimum dose	1153:1168	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish	1153:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	5	33	theme	optimum	1157:1163	arg1	8.95 g/kg					1253:1261	8.95 g/kg	1253:1261	8.95 g/kg	1253:1261	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	1	34	theme	concentrations	204:217	arg1	effects					175:181	the effects	171:181	the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco)	171:359	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	35	theme	catalase	688:695	arg1	activity					697:704	catalase activity	688:704	catalase activity	688:704	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	35	theme	catalase	688:695	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	1	36	dep	performance	245:255	arg1	the					234:236	the	234:236	the	234:236	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	2	37	theme	diets	389:393	arg1	kinds					367:371	Four kinds	362:371	Four kinds of experimental diets	362:393	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	0	38	theme	growth	31:36	arg1	performance					38:48	growth performance	31:48	growth performance	31:48	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	39	theme	juvenile	311:318	arg1	catfish					327:333	juvenile yellow catfish	311:333	juvenile yellow catfish (Pelteobagrus fulvidraco)	311:359	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	39	theme	juvenile	311:318	arg1	fulvidraco					349:358	fulvidraco	349:358	fulvidraco	349:358	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	40	theme	glutathione	707:717	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	40	theme	glutathione	707:717	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	41	theme	lysozyme	740:747	arg1	activity					749:756	lysozyme activity	740:756	lysozyme activity	740:756	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	41	theme	lysozyme	740:747	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	42	theme	control	920:926	arg1	group					928:932	the control group	916:932	the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05)	916:1061	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	1	43	theme	chitosan	222:229	arg1	concentrations					204:217	feeding different concentrations	186:217	feeding different concentrations of chitosan	186:229	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	0	44	theme	body	51:54	arg1	composition					56:66	body composition	51:66	body composition	51:66	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	45	theme	yellow	320:325	arg1	catfish					327:333	juvenile yellow catfish	311:333	juvenile yellow catfish (Pelteobagrus fulvidraco)	311:359	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	45	theme	yellow	320:325	arg1	fulvidraco					349:358	fulvidraco	349:358	fulvidraco	349:358	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	3	46	theme	specific	592:599	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	46	theme	specific	592:599	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	0	47	dep	performance	38:48	arg1	the					27:29	the	27:29	the	27:29	Dietary chitosan modulates the growth performance, body composition and nonspecific immunity of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	5	48	theme	juvenile	1225:1232	arg1	catfish					1241:1247	juvenile yellow catfish	1225:1247	juvenile yellow catfish	1225:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	1	49	theme	catfish	327:333	arg1	function					299:306	non-specific immune function	279:306	non-specific immune function	279:306	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	49	theme	catfish	327:333	arg1	performance					245:255	growth performance	238:255	growth performance	238:255	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	1	49	theme	catfish	327:333	arg1	composition					263:273	body composition	258:273	body composition	258:273	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	2	50	theme	yellow	519:524	arg1	catfish					526:532	juvenile yellow catfish	510:532	juvenile yellow catfish for 8 weeks	510:544	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	3	51	dep	diet	871:874	arg1	higher					895:900	higher	895:900	higher	895:900	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	52	theme	peroxidise	719:728	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	52	theme	peroxidise	719:728	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	5	53	theme	yellow	1234:1239	arg1	catfish					1241:1247	juvenile yellow catfish	1225:1247	juvenile yellow catfish	1225:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	3	54	theme	gain	581:584	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	activity					697:704	catalase activity	688:704	catalase activity	688:704	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	rate					623:626	survival rate	614:626	survival rate	614:626	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	54	theme	gain	581:584	arg1	activity					749:756	lysozyme activity	740:756	lysozyme activity	740:756	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	5	55	theme	catfish	1241:1247	arg1	growth					1215:1220	the maximum growth	1203:1220	the maximum growth of juvenile yellow catfish	1203:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35839947	3	56	theme	experimental	825:836	arg1	group					838:842	the experimental group	821:842	the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05)	821:1061	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	6	57	theme	body	1419:1422	arg1	composition					1424:1434	body composition	1419:1434	body composition	1419:1434	Therefore, adding an appropriate amount of chitosan (8.95 g/kg) to the feed of yellow catfish can significantly improve its growth performance, ameliorate body composition and enhance its non-specific immunity.					
35839947	3	58	theme	36.22 	947:952	arg1	P < 0.05					1053:1060	P < 0.05	1053:1060	P < 0.05	1053:1060	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	58	theme	36.22 	947:952	arg1	%					953:953	36.22 %	947:953	36.22 %	947:953	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	59	theme	disease	762:768	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	59	theme	disease	762:768	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	60	theme	79.71 	1030:1035	arg1	%					1036:1036	79.71 %	1030:1036	79.71 %	1030:1036	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	61	theme	survival	614:621	arg1	rate					623:626	survival rate	614:626	survival rate	614:626	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	61	theme	survival	614:621	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	activity					697:704	catalase activity	688:704	catalase activity	688:704	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	rate					623:626	survival rate	614:626	survival rate	614:626	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	62	theme	body	569:572	arg1	activity					749:756	lysozyme activity	740:756	lysozyme activity	740:756	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	2	63	theme	experimental	376:387	arg1	diets					389:393	experimental diets	376:393	experimental diets	376:393	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	3	64	dep	show	555:558	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	activity					697:704	catalase activity	688:704	catalase activity	688:704	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	rate					623:626	survival rate	614:626	survival rate	614:626	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	64	dep	show	555:558	arg1	activity					749:756	lysozyme activity	740:756	lysozyme activity	740:756	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	1	65	theme	growth	238:243	arg1	performance					245:255	growth performance	238:255	growth performance	238:255	This study investigated the effects of feeding different concentrations of chitosan on the growth performance, body composition and non-specific immune function of juvenile yellow catfish (Pelteobagrus fulvidraco).					
35839947	2	66	theme	chitosan	472:479	arg1	chitosan					472:479	chitosan	472:479	chitosan	472:479	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	2	66	theme	chitosan	472:479	arg1	0					432:432	0	432:432	0	432:432	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	2	66	theme	chitosan	472:479	arg1	group					443:447	control group	435:447	control group	435:447	Four kinds of experimental diets were respectively prepared by adding 0 (control group), 5, 10 and 15 g/kg of chitosan to the basal feed and fed to juvenile yellow catfish for 8 weeks.					
35839947	3	67	with	group	838:842	arg1	chitosan					849:856	chitosan	849:856	chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05)	849:1061	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	activity					678:685	serum superoxide dismutase activity	651:685	serum superoxide dismutase activity	651:685	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	rate					608:611	specific growth rate	592:611	specific growth rate	592:611	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	activity					730:737	glutathione peroxidise activity	707:737	glutathione peroxidise activity	707:737	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	content					642:648	body protein content	629:648	body protein content	629:648	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	ability					781:787	disease resistance ability	762:787	disease resistance ability	762:787	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	rate					586:589	the body weight gain rate	565:589	the body weight gain rate	565:589	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	activity					697:704	catalase activity	688:704	catalase activity	688:704	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	rate					623:626	survival rate	614:626	survival rate	614:626	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	3	68	theme	weight	574:579	arg1	activity					749:756	lysozyme activity	740:756	lysozyme activity	740:756	Results show that the body weight gain rate, specific growth rate, survival rate, body protein content, serum superoxide dismutase activity, catalase activity, glutathione peroxidise activity, lysozyme activity and disease resistance ability against Aeromonas hydrophila of the experimental group with chitosan added to its diet were significantly higher than those of the control group optimally by 36.22 %, 14.37 %, 9.46 %, 8.97 %, 50.89 %, 33.15 %, 21.52 %, 40.80 %, 41.09 %, and 79.71 %, respectively (P < 0.05).					
35839947	5	69	theme	maximum	1207:1213	arg1	growth					1215:1220	the maximum growth	1203:1220	the maximum growth of juvenile yellow catfish	1203:1247	The optimum dose of dietary chitosan required for the maximum growth of juvenile yellow catfish was 8.95 g/kg.					
35840239	10	0	theme	product	1334:1340	arg1	development					1292:1302	the development	1288:1302	the development of a synbiotic fermented meat product	1288:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	1	1	theme	prebiotic	130:138	arg1	inulin					140:145	the prebiotic inulin	126:145	the prebiotic inulin to synbiotic dry coppa	126:168	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	1	2	from	Lactis	72:77	arg1	form					117:120	free and microencapsulated form	90:120	free and microencapsulated form	90:120	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	7	3	contain	had	926:928	arg1	SYNB					901:904	SYNB	901:904	SYNB	901:904	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	3	contain	had	926:928	arg1	ENPROB					907:912	ENPROB	907:912	ENPROB	907:912	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	3	contain	had	926:928	arg1	treatments					884:893	The treatments PROB, SYNB, ENPROB, and ENSYNB	880:924	The treatments PROB, SYNB, ENPROB, and ENSYNB	880:924	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	3	contain	had	926:928	arg1	PROB					895:898	PROB	895:898	PROB	895:898	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	3	contain	had	926:928	arg2	counts					942:947	viable cell counts	930:947	viable cell counts	930:947	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	3	contain	had	926:928	arg1	ENSYNB					919:924	ENSYNB	919:924	ENSYNB	919:924	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	6	4	theme	oxidation	862:870	arg1	levels					872:877	lower lipid and protein oxidation levels	838:877	levels	872:877	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
35840239	10	5	theme	meat	1329:1332	arg1	product					1334:1340	a synbiotic fermented meat product	1307:1340	a synbiotic fermented meat product	1307:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	3	6	theme	coppa	325:329	arg1	formulations					331:342	synbiotic dry coppa formulations	311:342	synbiotic dry coppa formulations	311:342	Lactis (BB-12) strains to synbiotic dry coppa formulations was evaluated during 45 days of ripening.					
35840239	6	7	theme	protein	854:860	arg1	levels					872:877	lower lipid and protein oxidation levels	838:877	levels	872:877	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
35840239	10	8	theme	fermented	1319:1327	arg1	product					1334:1340	a synbiotic fermented meat product	1307:1340	a synbiotic fermented meat product	1307:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	1	9	from	inulin	140:145	arg1	form					117:120	free and microencapsulated form	90:120	free and microencapsulated form	90:120	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	2	10	theme	animalis	269:276	arg1	subsp					278:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	5	11	theme	weight	740:745	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	11	theme	weight	740:745	arg1	loss					747:750	weight loss	740:750	weight loss	740:750	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	10	12	theme	synbiotic	1309:1317	arg1	product					1334:1340	a synbiotic fermented meat product	1307:1340	a synbiotic fermented meat product	1307:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	2	13	theme	Bifidobacterium	253:267	arg1	subsp					278:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	3	14	theme	synbiotic	311:319	arg1	formulations					331:342	synbiotic dry coppa formulations	311:342	synbiotic dry coppa formulations	311:342	Lactis (BB-12) strains to synbiotic dry coppa formulations was evaluated during 45 days of ripening.					
35840239	8	15	theme	saline	1099:1104	arg1	solution					1106:1113	saline solution	1099:1113	saline solution	1099:1113	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	7	16	dep	treatments	884:893	arg1	PROB					895:898	PROB	895:898	PROB	895:898	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	16	dep	treatments	884:893	arg1	ENPROB					907:912	ENPROB	907:912	ENPROB	907:912	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	16	dep	treatments	884:893	arg1	ENSYNB					919:924	ENSYNB	919:924	ENSYNB	919:924	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	16	dep	treatments	884:893	arg1	SYNB					901:904	SYNB	901:904	SYNB	901:904	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	7	16	dep	treatments	884:893	arg1	treatments					884:893	The treatments PROB, SYNB, ENPROB, and ENSYNB	880:924	The treatments PROB, SYNB, ENPROB, and ENSYNB	880:924	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	2	17	theme	microencapsulated	235:251	arg1	subsp					278:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	9	18	theme	sensory	1218:1224	arg1	evaluation					1226:1235	the sensory evaluation	1214:1235	the sensory evaluation	1214:1235	The sample SYNB was the most accepted by the assessors in the sensory evaluation.					
35840239	3	19	theme	ripening	376:383	arg1	45 days					365:371	45 days	365:371	45 days of ripening	365:383	Lactis (BB-12) strains to synbiotic dry coppa formulations was evaluated during 45 days of ripening.					
35840239	6	20	theme	lower	838:842	arg1	lipid					844:848	lower lipid and protein oxidation levels	838:877	lipid	844:848	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
35840239	8	21	dep	survival	1067:1074	arg1	capacity					1087:1094	capacity	1087:1094	capacity	1087:1094	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	1	22	theme	synbiotic	150:158	arg1	coppa					164:168	synbiotic dry coppa	150:168	synbiotic dry coppa	150:168	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	4	23	dep	probiotic	508:516	arg1	free					503:506	free	503:506	free	503:506	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	5	24	dep	characteristics	700:714	arg1	color					795:799	instrumental color	782:799	instrumental color	782:799	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	aw					773:774	aw	773:774	aw	773:774	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	loss					747:750	weight loss	740:750	weight loss	740:750	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	pH					753:754	pH	753:754	pH	753:754	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	composition					727:737	proximate composition	717:737	proximate composition	717:737	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	24	dep	characteristics	700:714	arg1	activity					763:770	water activity	757:770	water activity (aw)	757:775	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	1	25	theme	dry	160:162	arg1	coppa					164:168	synbiotic dry coppa	150:168	synbiotic dry coppa	150:168	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	0	26	theme	addition	14:21	arg1	Effect					0:5	Effect	0:5	Effect of the addition of the probiotic Bifidobacterium animalis subsp.	0:70	Effect of the addition of the probiotic Bifidobacterium animalis subsp.					
35840239	4	27	theme	probiotic	508:516	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	5	28	theme	adequate	675:682	arg1	color					795:799	instrumental color	782:799	instrumental color	782:799	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	28	theme	adequate	675:682	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	28	theme	adequate	675:682	arg1	loss					747:750	weight loss	740:750	weight loss	740:750	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	28	theme	adequate	675:682	arg1	pH					753:754	pH	753:754	pH	753:754	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	28	theme	adequate	675:682	arg1	composition					727:737	proximate composition	717:737	proximate composition	717:737	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	28	theme	adequate	675:682	arg1	activity					763:770	water activity	757:770	water activity (aw)	757:775	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	8	29	theme	low	1122:1124	arg1	values					1129:1134	low pH values	1122:1134	low pH values for all treatments	1122:1153	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	4	30	with	SYNB	493:496	arg1	probiotic					560:568	probiotic	560:568	probiotic	560:568	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	30	with	SYNB	493:496	arg1	inulin					619:624	inulin	619:624	inulin	619:624	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	30	with	SYNB	493:496	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	30	with	SYNB	493:496	arg1	probiotic					605:613	probiotic	605:613	probiotic	605:613	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	30	with	SYNB	493:496	arg1	probiotic					482:490	probiotic	482:490	probiotic	482:490	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	5	31	theme	instrumental	782:793	arg1	color					795:799	instrumental color	782:799	instrumental color	782:799	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	31	theme	instrumental	782:793	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	color					795:799	instrumental color	782:799	instrumental color	782:799	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	loss					747:750	weight loss	740:750	weight loss	740:750	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	pH					753:754	pH	753:754	pH	753:754	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	composition					727:737	proximate composition	717:737	proximate composition	717:737	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	32	theme	physicochemical	684:698	arg1	activity					763:770	water activity	757:770	water activity (aw)	757:775	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	4	33	theme	control	424:430	arg1	C					432:432	control C	424:432	control C without probiotic and prebiotic	424:464	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	5	34	theme	water	757:761	arg1	aw					773:774	aw	773:774	aw	773:774	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	34	theme	water	757:761	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	34	theme	water	757:761	arg1	activity					763:770	water activity	757:770	water activity (aw)	757:775	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	8	35	theme	gastrointestinal	1014:1029	arg1	simulation					1031:1040	the in vitro gastrointestinal simulation	1001:1040	the in vitro gastrointestinal simulation	1001:1040	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	10	36	used	used	1266:1269	arg2	coppa					1253:1257	dry coppa	1249:1257	dry coppa	1249:1257	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	10	36	used	used	1266:1269	arg2	vehicle					1276:1282	a vehicle	1274:1282	a vehicle for the development of a synbiotic fermented meat product	1274:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	8	37	theme	pH	1126:1127	arg1	values					1129:1134	low pH values	1122:1134	low pH values for all treatments	1122:1153	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	9	38	from	assessors	1201:1209	arg1	evaluation					1226:1235	the sensory evaluation	1214:1235	the sensory evaluation	1214:1235	The sample SYNB was the most accepted by the assessors in the sensory evaluation.					
35840239	4	39	with	ENSYNB	575:580	arg1	probiotic					560:568	probiotic	560:568	probiotic	560:568	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	39	with	ENSYNB	575:580	arg1	inulin					619:624	inulin	619:624	inulin	619:624	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	39	with	ENSYNB	575:580	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	39	with	ENSYNB	575:580	arg1	probiotic					605:613	probiotic	605:613	probiotic	605:613	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	39	with	ENSYNB	575:580	arg1	probiotic					482:490	probiotic	482:490	probiotic	482:490	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	10	40	theme	dry	1249:1251	arg1	vehicle					1276:1282	a vehicle	1274:1282	a vehicle for the development of a synbiotic fermented meat product	1274:1340	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	10	40	theme	dry	1249:1251	arg1	coppa					1253:1257	dry coppa	1249:1257	dry coppa	1249:1257	Therefore, dry coppa can be used as a vehicle for the development of a synbiotic fermented meat product.					
35840239	3	41	theme	dry	321:323	arg1	formulations					331:342	synbiotic dry coppa formulations	311:342	synbiotic dry coppa formulations	311:342	Lactis (BB-12) strains to synbiotic dry coppa formulations was evaluated during 45 days of ripening.					
35840239	0	42	theme	Bifidobacterium	40:54	arg1	subsp					65:69	the probiotic Bifidobacterium animalis subsp	26:69	the probiotic Bifidobacterium animalis subsp	26:69	Effect of the addition of the probiotic Bifidobacterium animalis subsp.					
35840239	5	43	theme	proximate	717:725	arg1	characteristics					700:714	adequate physicochemical characteristics	675:714	adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color)	675:800	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	5	43	theme	proximate	717:725	arg1	composition					727:737	proximate composition	717:737	proximate composition	717:737	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	3	44	theme	Lactis	285:290	arg1	strains					300:306	Lactis (BB-12) strains	285:306	Lactis (BB-12) strains to synbiotic dry coppa formulations	285:342	Lactis (BB-12) strains to synbiotic dry coppa formulations was evaluated during 45 days of ripening.					
35840239	9	45	theme	sample	1160:1165	arg1	SYNB					1167:1170	The sample SYNB	1156:1170	The sample SYNB	1156:1170	The sample SYNB was the most accepted by the assessors in the sensory evaluation.					
35840239	2	46	theme	addition	189:196	arg1	effect					175:180	The effect	171:180	The effect of the addition of the prebiotic inulin	171:220	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	8	47	theme	BB-12	1047:1051	arg1	strain					1053:1058	the BB-12 strain	1043:1058	the BB-12 strain	1043:1058	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	1	48	theme	free	90:93	arg1	form					117:120	free and microencapsulated form	90:120	free and microencapsulated form	90:120	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	0	49	theme	probiotic	30:38	arg1	subsp					65:69	the probiotic Bifidobacterium animalis subsp	26:69	the probiotic Bifidobacterium animalis subsp	26:69	Effect of the addition of the probiotic Bifidobacterium animalis subsp.					
35840239	8	50	theme	in	1005:1006	arg1	simulation					1031:1040	the in vitro gastrointestinal simulation	1001:1040	the in vitro gastrointestinal simulation	1001:1040	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	7	51	theme	cell	937:940	arg1	counts					942:947	viable cell counts	930:947	viable cell counts	930:947	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	2	52	dep	subsp	278:282	arg1	effect					175:180	The effect	171:180	The effect of the addition of the prebiotic inulin	171:220	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	4	53	with	ENPROB	530:535	arg1	probiotic					560:568	probiotic	560:568	probiotic	560:568	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	53	with	ENPROB	530:535	arg1	inulin					619:624	inulin	619:624	inulin	619:624	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	53	with	ENPROB	530:535	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	53	with	ENPROB	530:535	arg1	probiotic					605:613	probiotic	605:613	probiotic	605:613	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	53	with	ENPROB	530:535	arg1	probiotic					482:490	probiotic	482:490	probiotic	482:490	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	5	54	theme	BB-12	648:652	arg1	incorporation					631:643	The incorporation	627:643	The incorporation of BB-12 with inulin	627:664	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	4	55	theme	following	390:398	arg1	formulations					400:411	The following formulations	386:411	The following formulations	386:411	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	2	56	theme	free	226:229	arg1	subsp					278:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	and free and microencapsulated Bifidobacterium animalis subsp	222:282	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	1	57	theme	microencapsulated	99:115	arg1	form					117:120	free and microencapsulated form	90:120	free and microencapsulated form	90:120	Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.					
35840239	4	58	with	PROB	467:470	arg1	probiotic					560:568	probiotic	560:568	probiotic	560:568	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	58	with	PROB	467:470	arg1	inulin					619:624	inulin	619:624	inulin	619:624	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	58	with	PROB	467:470	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	58	with	PROB	467:470	arg1	probiotic					605:613	probiotic	605:613	probiotic	605:613	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	58	with	PROB	467:470	arg1	probiotic					482:490	probiotic	482:490	probiotic	482:490	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	0	59	theme	subsp	65:69	arg1	addition					14:21	the addition	10:21	the addition of the probiotic Bifidobacterium animalis subsp	10:69	Effect of the addition of the probiotic Bifidobacterium animalis subsp.					
35840239	2	60	theme	inulin	215:220	arg1	addition					189:196	the addition	185:196	the addition of the prebiotic inulin	185:220	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	7	61	theme	viable	930:935	arg1	counts					942:947	viable cell counts	930:947	viable cell counts	930:947	The treatments PROB, SYNB, ENPROB, and ENSYNB had viable cell counts above 109 CFU/g and can be considered probiotic.					
35840239	5	62	with	incorporation	631:643	arg1	inulin					659:664	inulin	659:664	inulin	659:664	The incorporation of BB-12 with inulin provided adequate physicochemical characteristics (proximate composition, weight loss, pH, water activity (aw), and instrumental color).					
35840239	4	63	with	C	432:432	arg1	probiotic					560:568	probiotic	560:568	probiotic	560:568	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	63	with	C	432:432	arg1	inulin					619:624	inulin	619:624	inulin	619:624	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	63	with	C	432:432	arg1	inulin					522:527	free probiotic and inulin	503:527	free probiotic and inulin	503:527	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	63	with	C	432:432	arg1	probiotic					605:613	probiotic	605:613	probiotic	605:613	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	4	63	with	C	432:432	arg1	probiotic					482:490	probiotic	482:490	probiotic	482:490	The following formulations were made: control C without probiotic and prebiotic; PROB with free probiotic; SYNB with free probiotic and inulin; ENPROB with microencapsulated probiotic, and ENSYNB with microencapsulated probiotic and inulin.					
35840239	0	64	theme	animalis	56:63	arg1	subsp					65:69	the probiotic Bifidobacterium animalis subsp	26:69	the probiotic Bifidobacterium animalis subsp	26:69	Effect of the addition of the probiotic Bifidobacterium animalis subsp.					
35840239	2	65	theme	prebiotic	205:213	arg1	inulin					215:220	the prebiotic inulin	201:220	the prebiotic inulin	201:220	The effect of the addition of the prebiotic inulin and free and microencapsulated Bifidobacterium animalis subsp.					
35840239	8	66	dep	in	1005:1006	arg1	vitro					1008:1012	vitro	1008:1012	vitro	1008:1012	In the in vitro gastrointestinal simulation, the BB-12 strain showed survival and growth capacity in saline solution and at low pH values for all treatments.					
35840239	6	67	dep	treatments	807:816	arg1	PRO					818:820	PRO	818:820	PRO	818:820	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
35840239	6	67	dep	treatments	807:816	arg1	treatments					807:816	The treatments PRO and SYNB	803:829	The treatments PRO and SYNB	803:829	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
35840239	6	67	dep	treatments	807:816	arg1	SYNB					826:829	SYNB	826:829	SYNB	826:829	The treatments PRO and SYNB showed lower lipid and protein oxidation levels.					
37071083	6	0	dep	RESULTS	1054:1060	arg1	RESULTS					1054:1060	RESULTS SLK1 and SLK5	1054:1074	RESULTS SLK1 and SLK5	1054:1074	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	6	0	dep	RESULTS	1054:1060	arg1	SLK5					1071:1074	SLK5	1071:1074	SLK5	1071:1074	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	6	0	dep	RESULTS	1054:1060	arg1	SLK1					1062:1065	SLK1	1062:1065	SLK1	1062:1065	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	0	1	theme	weaned	194:199	arg1	piglets					201:207	weaned piglets	194:207	weaned piglets	194:207	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	3	2	theme	/attapulgite	485:496	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	5	3	theme	barrier	985:991	arg1	function					993:1000	intestinal epithelial barrier function	963:1000	intestinal epithelial barrier function	963:1000	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	4	4	theme	100 g·kg	723:730	arg1	MOS					735:737	100 g·kg -1 MOS	723:737	100 g·kg -1 MOS	723:737	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	4	theme	100 g·kg	723:730	arg1	SLK3					718:721	SLK3	718:721	SLK3(100 g·kg -1 MOS)	718:738	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	7	5	theme	weaned	1208:1213	arg1	piglets					1215:1221	weaned piglets	1208:1221	weaned piglets	1208:1221	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	5	6	dep	antibiotic	846:855	arg1	substitutes					857:867	substitutes	857:867	substitutes	857:867	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	4	7	contain	contains	629:636	arg2	E					651:651	50 g vitamin E	638:651	50 g vitamin E	638:651	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	7	contain	contains	629:636	arg1	kg					603:604	Each kg	598:604	Each kg of SLK1, SLK3, or SLK5	598:627	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	3	8	theme	nanocomposites	504:517	arg1	effect					431:436	the effect	427:436	the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets	427:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	7	9	theme	TAS	1240:1242	arg1	group					1244:1248	TAS group	1240:1248	TAS group (P < 0.05)	1240:1259	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	7	9	theme	TAS	1240:1242	arg1	P < 0.05					1251:1258	P < 0.05	1251:1258	P < 0.05	1251:1258	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	2	10	theme	new	328:330	arg1	way					332:334	a new way	326:334	a new way to ensure animal health	326:358	Therefore, it's necessary to find a new way to ensure animal health, and promote animal growth.					
37071083	1	11	theme	BACKGROUND	210:219	arg1	Overuse					221:227	BACKGROUND Overuse	210:227	BACKGROUND Overuse of antibiotics	210:242	BACKGROUND Overuse of antibiotics contributes to bacterial resistance in animals.					
37071083	13	12	theme	microbiota	1979:1988	arg1	composition					1990:2000	intestinal microbiota composition	1968:2000	intestinal microbiota composition to prevent diarrhea in weaned piglets	1968:2038	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	5	13	dep	group	817:821	arg1	group					915:919	SLK5 group	910:919	SLK5 group	910:919	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	13	dep	group	817:821	arg1	group					875:879	Traditional antibiotic substitutes (TAS) group	834:879	Traditional antibiotic substitutes (TAS) group	834:879	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	13	dep	group	817:821	arg1	group					887:891	SLK1 group	882:891	SLK1 group	882:891	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	13	dep	group	817:821	arg1	group					899:903	SLK3 group	894:903	SLK3 group	894:903	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	13	dep	group	817:821	arg1	group					827:831	NC group	824:831	NC group	824:831	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	0	14	theme	microbiota	148:157	arg1	composition					159:169	intestinal microbiota composition	137:169	intestinal microbiota composition to prevent diarrhea in weaned piglets	137:207	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	4	15	theme	50 g	638:641	arg1	E					651:651	50 g vitamin E	638:651	50 g vitamin E	638:651	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	3	16	dep	nanocomposites	504:517	arg1	SLK3					526:529	SLK3	526:529	SLK3	526:529	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	16	dep	nanocomposites	504:517	arg1	SLK1					520:523	SLK1	520:523	SLK1	520:523	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	16	dep	nanocomposites	504:517	arg1	SLK5					532:535	SLK5	532:535	SLK5	532:535	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	5	17	theme	SLK5	910:913	arg1	group					915:919	SLK5 group	910:919	SLK5 group	910:919	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	3	18	theme	intestinal	561:570	arg1	performance					548:558	growth performance	541:558	growth performance	541:558	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	18	theme	intestinal	561:570	arg1	health					572:577	intestinal health	561:577	intestinal health in weaned piglets	561:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	4	19	dep	concentration	681:693	arg1	SLK1					696:699	SLK1	696:699	SLK1(50 g·kg -1 MOS)	696:715	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	19	dep	concentration	681:693	arg1	SLK5					741:744	SLK5	741:744	SLK5(150 g·kg -1 MOS)	741:761	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	19	dep	concentration	681:693	arg1	MOS					712:714	50 g·kg -1 MOS	701:714	50 g·kg -1 MOS	701:714	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	19	dep	concentration	681:693	arg1	SLK3					718:721	SLK3	718:721	SLK3(100 g·kg -1 MOS)	718:738	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	20	theme	SLK5	624:627	arg1	kg					603:604	Each kg	598:604	Each kg of SLK1, SLK3, or SLK5	598:627	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	13	21	theme	barrier	1936:1942	arg1	function					1944:1951	intestinal epithelial barrier function	1914:1951	intestinal epithelial barrier function	1914:1951	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	4	22	theme	MOS	677:679	arg1	concentration					681:693	different MOS concentration	667:693	different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS))	667:762	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	0	23	theme	intestinal	95:104	arg1	barrier					117:123	intestinal epithelial barrier	95:123	intestinal epithelial barrier	95:123	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	5	24	theme	SLK3	894:897	arg1	group					899:903	SLK3 group	894:903	SLK3 group	894:903	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	12	25	theme	propionate	1748:1757	arg1	contents					1759:1766	propionate contents	1748:1766	propionate contents	1748:1766	In addition, dietary supplementation with 1 kg•T-1 SLK5 also significantly increased propionate contents in colon, which is significantly correlated with phascolarctobacterium (P < 0.05).					
37071083	8	26	theme	villus	1293:1298	arg1	height					1300:1305	villus height	1293:1305	villus height of ileum	1293:1314	Furtherly, SLK5 also increased villus height of ileum, and increased goblet number of jejunum (P < 0.05).					
37071083	9	27	dep	intestinal	1430:1439	arg1	colonic					1441:1447	colonic	1441:1447	colonic	1441:1447	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	5	28	theme	diarrhea	947:954	arg1	index					956:960	diarrhea index	947:960	diarrhea index	947:960	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	29	theme	135	776:778	arg1	piglets					780:786	135 piglets	776:786	135 piglets	776:786	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	3	30	theme	MOS	465:467	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	13	31	from	diarrhea	2013:2020	arg1	piglets					2032:2038	weaned piglets	2025:2038	weaned piglets	2025:2038	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	3	32	theme	oligosaccharide	448:462	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	0	33	theme	attapulgite	31:41	arg1	nanocomposites					4:17	The nanocomposites	0:17	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide	0:83	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	0	33	theme	attapulgite	31:41	arg1	attapulgite					31:41	modified attapulgite	22:41	modified attapulgite with Vitamin E and Mannan oligosaccharide	22:83	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	12	34	theme	dietary	1676:1682	arg1	supplementation					1684:1698	dietary supplementation	1676:1698	dietary supplementation with 1 kg•T-1 SLK5	1676:1717	In addition, dietary supplementation with 1 kg•T-1 SLK5 also significantly increased propionate contents in colon, which is significantly correlated with phascolarctobacterium (P < 0.05).					
37071083	13	35	theme	CONCLUSION	1851:1860	arg1	supplementation					1870:1884	CONCLUSION Dietary supplementation	1851:1884	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5	1851:1903	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	0	36	theme	Vitamin	48:54	arg1	E					56:56	Vitamin E	48:56	Vitamin E	48:56	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	13	37	theme	intestinal	1914:1923	arg1	function					1944:1951	intestinal epithelial barrier function	1914:1951	intestinal epithelial barrier function	1914:1951	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	9	38	theme	16 s	1368:1371	arg1	sequencing					1378:1387	16 s rRNA sequencing	1368:1387	16 s rRNA sequencing	1368:1387	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	8	39	theme	jejunum	1348:1354	arg1	number					1338:1343	goblet number	1331:1343	goblet number of jejunum (P < 0.05)	1331:1365	Furtherly, SLK5 also increased villus height of ileum, and increased goblet number of jejunum (P < 0.05).					
37071083	3	40	theme	/vitamin	470:477	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	12	41	with	supplementation	1684:1698	arg1	SLK5					1714:1717	1 kg•T-1 SLK5	1705:1717	1 kg•T-1 SLK5	1705:1717	In addition, dietary supplementation with 1 kg•T-1 SLK5 also significantly increased propionate contents in colon, which is significantly correlated with phascolarctobacterium (P < 0.05).					
37071083	3	42	from	effect	431:436	arg1	performance					548:558	growth performance	541:558	growth performance	541:558	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	42	from	effect	431:436	arg1	health					572:577	intestinal health	561:577	intestinal health in weaned piglets	561:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	2	43	theme	animal	373:378	arg1	growth					380:385	animal growth	373:385	animal growth	373:385	Therefore, it's necessary to find a new way to ensure animal health, and promote animal growth.					
37071083	5	44	theme	microbial	1018:1026	arg1	composition					1028:1038	intestinal microbial composition	1007:1038	intestinal microbial composition	1007:1038	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	0	45	with	attapulgite	31:41	arg1	Mannan					62:67	Mannan	62:67	Mannan	62:67	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	0	45	with	attapulgite	31:41	arg1	E					56:56	Vitamin E	48:56	Vitamin E	48:56	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	5	46	theme	epithelial	974:983	arg1	function					993:1000	intestinal epithelial barrier function	963:1000	intestinal epithelial barrier function	963:1000	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	0	47	from	diarrhea	182:189	arg1	piglets					201:207	weaned piglets	194:207	weaned piglets	194:207	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	13	48	theme	weaned	2025:2030	arg1	piglets					2032:2038	weaned piglets	2025:2038	weaned piglets	2025:2038	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	9	49	theme	intestinal	1430:1439	arg1	P < 0.05					1473:1480	P < 0.05	1473:1480	P < 0.05	1473:1480	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	9	49	theme	intestinal	1430:1439	arg1	composition					1460:1470	intestinal colonic microbiota composition	1430:1470	intestinal colonic microbiota composition (P < 0.05)	1430:1481	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	7	50	dep	more	1156:1159	arg1	What					1149:1152	What	1149:1152	What	1149:1152	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	9	51	theme	microbiota	1449:1458	arg1	P < 0.05					1473:1480	P < 0.05	1473:1480	P < 0.05	1473:1480	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	9	51	theme	microbiota	1449:1458	arg1	composition					1460:1470	intestinal colonic microbiota composition	1430:1470	intestinal colonic microbiota composition (P < 0.05)	1430:1481	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	7	52	theme	piglets	1215:1221	arg1	rate					1200:1203	survival rate	1191:1203	survival rate of weaned piglets	1191:1221	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	4	53	theme	SLK1	609:612	arg1	kg					603:604	Each kg	598:604	Each kg of SLK1, SLK3, or SLK5	598:627	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	54	contain	had	663:665	arg1	they					658:661	they	658:661	they	658:661	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	54	contain	had	663:665	arg2	concentration					681:693	different MOS concentration	667:693	different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS))	667:762	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	0	55	theme	intestinal	137:146	arg1	composition					159:169	intestinal microbiota composition	137:169	intestinal microbiota composition to prevent diarrhea in weaned piglets	137:207	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	7	56	theme	survival	1191:1198	arg1	rate					1200:1203	survival rate	1191:1203	survival rate of weaned piglets	1191:1221	What's more, SLK5 significantly increased survival rate of weaned piglets as compared with TAS group (P < 0.05).					
37071083	2	57	theme	animal	346:351	arg1	health					353:358	animal health	346:358	animal health	346:358	Therefore, it's necessary to find a new way to ensure animal health, and promote animal growth.					
37071083	5	58	theme	SLK1	882:885	arg1	group					887:891	SLK1 group	882:891	SLK1 group	882:891	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	3	59	theme	growth	541:546	arg1	performance					548:558	growth performance	541:558	growth performance	541:558	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	59	theme	growth	541:546	arg1	health					572:577	intestinal health	561:577	intestinal health in weaned piglets	561:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	1	60	theme	antibiotics	232:242	arg1	Overuse					221:227	BACKGROUND Overuse	210:227	BACKGROUND Overuse of antibiotics	210:242	BACKGROUND Overuse of antibiotics contributes to bacterial resistance in animals.					
37071083	1	61	from	resistance	269:278	arg1	animals					283:289	animals	283:289	animals	283:289	BACKGROUND Overuse of antibiotics contributes to bacterial resistance in animals.					
37071083	11	62	theme	Bifidobacterium	1616:1630	arg1	abundance					1632:1640	Lactobacillus and Bifidobacterium abundance	1598:1640	Lactobacillus and Bifidobacterium abundance	1598:1640	succinatutens abundance in cecum, and increased Lactobacillus and Bifidobacterium abundance in colon (P < 0.05).					
37071083	4	63	theme	150 g·kg	746:753	arg1	MOS					758:760	150 g·kg -1 MOS	746:760	150 g·kg -1 MOS	746:760	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	63	theme	150 g·kg	746:753	arg1	SLK5					741:744	SLK5	741:744	SLK5(150 g·kg -1 MOS)	741:761	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	6	64	theme	diarrhea	1100:1107	arg1	frequency					1109:1117	diarrhea frequency	1100:1117	diarrhea frequency in weaned piglets (P < 0.05)	1100:1146	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	12	65	from	contents	1759:1766	arg1	colon					1771:1775	colon	1771:1775	colon	1771:1775	In addition, dietary supplementation with 1 kg•T-1 SLK5 also significantly increased propionate contents in colon, which is significantly correlated with phascolarctobacterium (P < 0.05).					
37071083	11	66	from	abundance	1564:1572	arg1	cecum					1577:1581	cecum	1577:1581	cecum	1577:1581	succinatutens abundance in cecum, and increased Lactobacillus and Bifidobacterium abundance in colon (P < 0.05).					
37071083	4	67	theme	vitamin	643:649	arg1	E					651:651	50 g vitamin E	638:651	50 g vitamin E	638:651	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	13	68	theme	intestinal	1968:1977	arg1	composition					1990:2000	intestinal microbiota composition	1968:2000	intestinal microbiota composition to prevent diarrhea in weaned piglets	1968:2038	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	4	69	theme	SLK3	615:618	arg1	kg					603:604	Each kg	598:604	Each kg of SLK1, SLK3, or SLK5	598:627	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	13	70	theme	epithelial	1925:1934	arg1	function					1944:1951	intestinal epithelial barrier function	1914:1951	intestinal epithelial barrier function	1914:1951	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	0	71	theme	epithelial	106:115	arg1	barrier					117:123	intestinal epithelial barrier	95:123	intestinal epithelial barrier	95:123	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	4	72	theme	different	667:675	arg1	concentration					681:693	different MOS concentration	667:693	different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS))	667:762	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	13	73	theme	1 kg•T-1	1891:1898	arg1	SLK5					1900:1903	1 kg•T-1 SLK5	1891:1903	1 kg•T-1 SLK5	1891:1903	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	12	74	theme	1 kg•T-1	1705:1712	arg1	SLK5					1714:1717	1 kg•T-1 SLK5	1705:1717	1 kg•T-1 SLK5	1705:1717	In addition, dietary supplementation with 1 kg•T-1 SLK5 also significantly increased propionate contents in colon, which is significantly correlated with phascolarctobacterium (P < 0.05).					
37071083	8	75	theme	ileum	1310:1314	arg1	height					1300:1305	villus height	1293:1305	villus height of ileum	1293:1314	Furtherly, SLK5 also increased villus height of ileum, and increased goblet number of jejunum (P < 0.05).					
37071083	1	76	theme	bacterial	259:267	arg1	resistance					269:278	bacterial resistance	259:278	bacterial resistance in animals	259:289	BACKGROUND Overuse of antibiotics contributes to bacterial resistance in animals.					
37071083	3	77	from	health	572:577	arg1	piglets					589:595	weaned piglets	582:595	weaned piglets	582:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	3	78	theme	mannan	441:446	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	11	79	theme	Lactobacillus	1598:1610	arg1	abundance					1632:1640	Lactobacillus and Bifidobacterium abundance	1598:1640	Lactobacillus and Bifidobacterium abundance	1598:1640	succinatutens abundance in cecum, and increased Lactobacillus and Bifidobacterium abundance in colon (P < 0.05).					
37071083	0	80	theme	modified	22:29	arg1	attapulgite					31:41	modified attapulgite	22:41	modified attapulgite with Vitamin E and Mannan oligosaccharide	22:83	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	5	81	theme	piglets	780:786	arg1	total					767:771	A total	765:771	A total of 135 piglets	765:786	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	8	82	theme	goblet	1331:1336	arg1	number					1338:1343	goblet number	1331:1343	goblet number of jejunum (P < 0.05)	1331:1365	Furtherly, SLK5 also increased villus height of ileum, and increased goblet number of jejunum (P < 0.05).					
37071083	13	83	with	supplementation	1870:1884	arg1	SLK5					1900:1903	1 kg•T-1 SLK5	1891:1903	1 kg•T-1 SLK5	1891:1903	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	5	84	theme	intestinal	963:972	arg1	function					993:1000	intestinal epithelial barrier function	963:1000	intestinal epithelial barrier function	963:1000	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	0	85	dep	E	56:56	arg1	oligosaccharide					69:83	oligosaccharide	69:83	oligosaccharide	69:83	The nanocomposites of modified attapulgite with Vitamin E and Mannan oligosaccharide regulated intestinal epithelial barrier and improve intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	3	86	theme	weaned	582:587	arg1	piglets					589:595	weaned piglets	582:595	weaned piglets	582:595	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	5	87	theme	growth	927:932	arg1	performance					934:944	growth performance	927:944	growth performance	927:944	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	88	theme	antibiotic	846:855	arg1	group					875:879	Traditional antibiotic substitutes (TAS) group	834:879	Traditional antibiotic substitutes (TAS) group	834:879	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	6	89	theme	weaned	1122:1127	arg1	piglets					1129:1135	weaned piglets	1122:1135	weaned piglets (P < 0.05)	1122:1146	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	6	89	theme	weaned	1122:1127	arg1	P < 0.05					1138:1145	P < 0.05	1138:1145	P < 0.05	1138:1145	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	13	90	theme	Dietary	1862:1868	arg1	supplementation					1870:1884	CONCLUSION Dietary supplementation	1851:1884	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5	1851:1903	CONCLUSION Dietary supplementation with 1 kg•T-1 SLK5 improved intestinal epithelial barrier function, and regulated intestinal microbiota composition to prevent diarrhea in weaned piglets.					
37071083	3	91	theme	VE	482:483	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	6	92	from	frequency	1109:1117	arg1	piglets					1129:1135	weaned piglets	1122:1135	weaned piglets (P < 0.05)	1122:1146	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	6	92	from	frequency	1109:1117	arg1	P < 0.05					1138:1145	P < 0.05	1138:1145	P < 0.05	1138:1145	RESULTS SLK1 and SLK5 significantly decreased diarrhea frequency in weaned piglets (P < 0.05).					
37071083	9	93	theme	rRNA	1373:1376	arg1	sequencing					1378:1387	16 s rRNA sequencing	1368:1387	16 s rRNA sequencing	1368:1387	16 s rRNA sequencing showed that SLK5 significantly regulated intestinal colonic microbiota composition (P < 0.05).					
37071083	3	94	theme	E	479:479	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
37071083	5	95	theme	intestinal	1007:1016	arg1	composition					1028:1038	intestinal microbial composition	1007:1038	intestinal microbial composition	1007:1038	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	5	96	theme	NC	824:825	arg1	group					827:831	NC group	824:831	NC group	824:831	A total of 135 piglets were randomly divided into 5 group (NC group, Traditional antibiotic substitutes (TAS) group, SLK1 group, SLK3 group, and SLK5 group), and growth performance, diarrhea index, intestinal epithelial barrier function, and intestinal microbial composition was measured.					
37071083	4	97	theme	50 g·kg	701:707	arg1	SLK1					696:699	SLK1	696:699	SLK1(50 g·kg -1 MOS)	696:715	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	4	97	theme	50 g·kg	701:707	arg1	MOS					712:714	50 g·kg -1 MOS	701:714	50 g·kg -1 MOS	701:714	Each kg of SLK1, SLK3, or SLK5 contains 50 g vitamin E, and they had different MOS concentration (SLK1(50 g·kg -1 MOS), SLK3(100 g·kg -1 MOS), SLK5(150 g·kg -1 MOS)).					
37071083	3	98	theme	APT	499:501	arg1	nanocomposites					504:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites	441:517	mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5)	441:536	This experiment was conducted to study the effect of mannan oligosaccharide (MOS) /vitamin E (VE)/attapulgite (APT) nanocomposites (SLK1, SLK3, SLK5) on growth performance, intestinal health in weaned piglets.					
35791071	4	0	theme	central	519:525	arg1	experiment					550:559	our central composite design (CCD) experiment	515:559	our central composite design (CCD) experiment	515:559	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	1	1	with	sugar	182:186	arg1	applications					200:211	potent applications	193:211	potent applications in the food, healthcare and biopharma industries	193:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	1	2	from	applications	200:211	arg1	industries					251:260	the food, healthcare and biopharma industries	216:260	the food, healthcare and biopharma industries	216:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	6	3	theme	one-pot	936:942	arg1	process					944:950	A one-pot process	934:950	A one-pot process integrating trehalose production and byproduct bioremoval	934:1008	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	0	4	theme	Pseudomonas	93:103	arg1	Cells					115:119	Permeabilized Pseudomonas monteilii Cells	79:119	Permeabilized Pseudomonas monteilii Cells	79:119	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	5	5	from	production	739:748	arg1	bioreactor					765:774	a lab-scale bioreactor	753:774	a lab-scale bioreactor	753:774	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	4	6	theme	g/g	674:676	arg1	yield					659:663	the maximum trehalose yield	637:663	the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l	637:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	4	7	theme	design	537:542	arg1	experiment					550:559	our central composite design (CCD) experiment	515:559	our central composite design (CCD) experiment	515:559	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	7	8	theme	24.85	1248:1252	arg1	g/l					1254:1256	g/l	1254:1256	g/l	1254:1256	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	4	9	theme	g/l	725:727	arg1	loading					711:717	an initial cell loading	695:717	an initial cell loading of 94 g/l	695:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	4	10	theme	maximum	641:647	arg1	yield					659:663	the maximum trehalose yield	637:663	the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l	637:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	4	11	theme	cell	706:709	arg1	loading					711:717	an initial cell loading	695:717	an initial cell loading of 94 g/l	695:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	0	12	from	Maltose	65:71	arg1	Production					49:58	Trehalose Production	39:58	Trehalose Production from Maltose	39:71	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	7	13	theme	Saccharomyces	1164:1176	arg1	12153					1194:1198	Saccharomyces cerevisiae TBRC 12153	1164:1198	Saccharomyces cerevisiae TBRC 12153	1164:1198	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	8	14	from	production	1366:1375	arg1	bio-industry					1399:1410	bio-industry	1399:1410	bio-industry	1399:1410	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	6	15	theme	permeabilized	1069:1081	arg1	cells					1095:1099	permeabilized P. moteilii cells	1069:1099	permeabilized P. moteilii cells	1069:1099	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	7	16	theme	g/l	1254:1256	arg1	ethanol					1258:1264	24.85 g/l ethanol	1248:1264	24.85 g/l ethanol obtained as a co-product	1248:1289	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	8	17	theme	present	1296:1302	arg1	work					1304:1307	The present work	1292:1307	The present work	1292:1307	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	1	18	theme	potent	193:198	arg1	applications					200:211	potent applications	193:211	potent applications in the food, healthcare and biopharma industries	193:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	5	19	theme	lab-scale	755:763	arg1	bioreactor					765:774	a lab-scale bioreactor	753:774	a lab-scale bioreactor	753:774	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	5	20	theme	final	787:791	arg1	concentration					803:815	the final trehalose concentration	783:815	the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	783:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	5	21	theme	g/l/h	881:885	arg1	productivity					860:871	productivity	860:871	productivity	860:871	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	5	21	theme	g/l/h	881:885	arg1	g/g					852:854	51.60 g/g	846:854	51.60 g/g	846:854	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	3	22	theme	%	466:466	arg1	X-100					475:479	1% Triton X-100	465:479	1% Triton X-100 permeabilized cells	465:499	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	0	23	theme	Whole-Cell	11:20	arg1	Biocatalysis					22:33	Whole-Cell Biocatalysis	11:33	Whole-Cell Biocatalysis for Trehalose Production from Maltose	11:71	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	5	24	theme	Scale-up	730:737	arg1	production					739:748	Scale-up production	730:748	Scale-up production in a lab-scale bioreactor	730:774	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	7	25	theme	%	1241:1241	arg1	recovery					1224:1231	trehalose recovery	1214:1231	trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product	1214:1289	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	7	26	dep	Saccharomyces	1164:1176	arg1	cerevisiae					1178:1187	cerevisiae	1178:1187	cerevisiae	1178:1187	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	2	27	theme	monteilii	346:354	arg1	biocatalyst					409:419	the biocatalyst	405:419	the biocatalyst	405:419	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	2	27	theme	monteilii	346:354	arg1	TBRC					356:359	whole-cell Pseudomonas monteilii TBRC 1196	323:364	whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS)	323:400	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	6	28	theme	%	1022:1022	arg1	yield					1034:1038	53.35% trehalose yield	1017:1038	53.35% trehalose yield from 107.4 g/l	1017:1053	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	4	29	theme	optimal	566:572	arg1	process					574:580	the optimal process	562:580	the optimal process	562:580	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	0	30	dep	Pseudomonas	93:103	arg1	monteilii					105:113	monteilii	105:113	monteilii	105:113	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	8	31	from	syrup	1390:1394	arg1	production					1366:1375	trehalose production	1356:1375	trehalose production from maltose syrup in bio-industry	1356:1410	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	4	32	theme	trehalose	649:657	arg1	yield					659:663	the maximum trehalose yield	637:663	the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l	637:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	4	33	theme	initial	698:704	arg1	loading					711:717	an initial cell loading	695:717	an initial cell loading of 94 g/l	695:727	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	5	34	with	concentration	803:815	arg1	yield					837:841	a yield	835:841	a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	835:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	2	35	theme	whole-cell	323:332	arg1	biocatalyst					409:419	the biocatalyst	405:419	the biocatalyst	405:419	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	2	35	theme	whole-cell	323:332	arg1	TBRC					356:359	whole-cell Pseudomonas monteilii TBRC 1196	323:364	whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS)	323:400	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	6	36	theme	trehalose	1024:1032	arg1	yield					1034:1038	53.35% trehalose yield	1017:1038	53.35% trehalose yield from 107.4 g/l	1017:1053	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	1	37	theme	food	220:223	arg1	industries					251:260	the food, healthcare and biopharma industries	216:260	the food, healthcare and biopharma industries	216:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	2	38	theme	Pseudomonas	334:344	arg1	biocatalyst					409:419	the biocatalyst	405:419	the biocatalyst	405:419	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	2	38	theme	Pseudomonas	334:344	arg1	TBRC					356:359	whole-cell Pseudomonas monteilii TBRC 1196	323:364	whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS)	323:400	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	0	39	theme	Byproduct	139:147	arg1	Bioremoval					125:134	Bioremoval	125:134	Bioremoval of Byproduct	125:147	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	0	39	theme	Byproduct	139:147	arg1	Cells					115:119	Permeabilized Pseudomonas monteilii Cells	79:119	Permeabilized Pseudomonas monteilii Cells	79:119	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	5	40	theme	g/g	852:854	arg1	yield					837:841	a yield	835:841	a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	835:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	5	41	theme	trehalose	793:801	arg1	concentration					803:815	the final trehalose concentration	783:815	the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	783:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	6	42	from	g/l	1051:1053	arg1	yield					1034:1038	53.35% trehalose yield	1017:1038	53.35% trehalose yield from 107.4 g/l	1017:1053	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	1	43	theme	healthcare	226:235	arg1	industries					251:260	the food, healthcare and biopharma industries	216:260	the food, healthcare and biopharma industries	216:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	6	44	theme	53.35	1017:1021	arg1	%					1022:1022	%	1022:1022	%	1022:1022	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	3	45	theme	Triton	468:473	arg1	X-100					475:479	1% Triton X-100	465:479	1% Triton X-100 permeabilized cells	465:499	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	0	46	theme	Trehalose	39:47	arg1	Production					49:58	Trehalose Production	39:58	Trehalose Production from Maltose	39:71	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	8	47	theme	alternative	1332:1342	arg1	process					1344:1350	an integrated alternative process	1318:1350	an integrated alternative process	1318:1350	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	3	48	theme	X-100	475:479	arg1	cells					495:499	1% Triton X-100 permeabilized cells	465:499	1% Triton X-100 permeabilized cells	465:499	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	4	49	theme	CCD	545:547	arg1	experiment					550:559	our central composite design (CCD) experiment	515:559	our central composite design (CCD) experiment	515:559	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	3	50	theme	1	465:465	arg1	%					466:466	%	466:466	%	466:466	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	8	51	theme	trehalose	1356:1364	arg1	production					1366:1375	trehalose production	1356:1375	trehalose production from maltose syrup in bio-industry	1356:1410	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	2	52	theme	trehalose	376:384	arg1	TreS					396:399	TreS	396:399	TreS	396:399	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	2	52	theme	trehalose	376:384	arg1	synthase					386:393	trehalose synthase	376:393	trehalose synthase (TreS)	376:400	In this study, trehalose was synthesized from maltose using whole-cell Pseudomonas monteilii TBRC 1196 producing trehalose synthase (TreS) as the biocatalyst.					
35791071	3	53	theme	reaction	426:433	arg1	condition					435:443	The reaction condition	422:443	The reaction condition	422:443	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	7	54	with	recovery	1224:1231	arg1	ethanol					1258:1264	24.85 g/l ethanol	1248:1264	24.85 g/l ethanol obtained as a co-product	1248:1289	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	5	55	theme	productivity	860:871	arg1	yield					837:841	a yield	835:841	a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	835:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	8	56	theme	maltose	1382:1388	arg1	syrup					1390:1394	maltose syrup	1382:1394	maltose syrup	1382:1394	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	7	57	theme	trehalose	1214:1222	arg1	recovery					1224:1231	trehalose recovery	1214:1231	trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product	1214:1289	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	6	58	theme	moteilii	1086:1093	arg1	cells					1095:1099	permeabilized P. moteilii cells	1069:1099	permeabilized P. moteilii cells	1069:1099	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	1	59	theme	biopharma	241:249	arg1	industries					251:260	the food, healthcare and biopharma industries	216:260	the food, healthcare and biopharma industries	216:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	5	60	theme	g/l	906:908	arg1	glucose					910:916	8.24 g/l glucose	901:916	8.24 g/l glucose as a byproduct	901:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	6	61	theme	trehalose	964:972	arg1	production					974:983	trehalose production	964:983	trehalose production	964:983	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35791071	0	62	theme	Permeabilized	79:91	arg1	Cells					115:119	Permeabilized Pseudomonas monteilii Cells	79:119	Permeabilized Pseudomonas monteilii Cells	79:119	Integrated Whole-Cell Biocatalysis for Trehalose Production from Maltose Using Permeabilized Pseudomonas monteilii Cells and Bioremoval of Byproduct.					
35791071	8	63	theme	integrated	1321:1330	arg1	process					1344:1350	an integrated alternative process	1318:1350	an integrated alternative process	1318:1350	The present work provides an integrated alternative process for trehalose production from maltose syrup in bio-industry.					
35791071	3	64	theme	permeabilized	481:493	arg1	cells					495:499	1% Triton X-100 permeabilized cells	465:499	1% Triton X-100 permeabilized cells	465:499	The reaction condition was optimized using 1% Triton X-100 permeabilized cells.					
35791071	5	65	theme	g/l	826:828	arg1	concentration					803:815	the final trehalose concentration	783:815	the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct	783:931	Scale-up production in a lab-scale bioreactor led to the final trehalose concentration of 51.91 g/l with a yield of 51.60 g/g and productivity of 4.37 g/l/h together with 8.24 g/l glucose as a byproduct.					
35791071	7	66	theme	TBRC	1189:1192	arg1	12153					1194:1198	Saccharomyces cerevisiae TBRC 12153	1164:1198	Saccharomyces cerevisiae TBRC 12153	1164:1198	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	4	67	theme	composite	527:535	arg1	experiment					550:559	our central composite design (CCD) experiment	515:559	our central composite design (CCD) experiment	515:559	According to our central composite design (CCD) experiment, the optimal process was achieved at 35°C and pH 8.0 for 24 h, resulting in the maximum trehalose yield of 51.60 g/g after 12 h using an initial cell loading of 94 g/l.					
35791071	7	68	theme	residual	1106:1113	arg1	maltose					1115:1121	The residual maltose and glucose	1102:1133	maltose	1115:1121	The residual maltose and glucose were subsequently removed by Saccharomyces cerevisiae TBRC 12153, resulting in trehalose recovery of 99.23% with 24.85 g/l ethanol obtained as a co-product.					
35791071	1	69	theme	non-conventional	165:180	arg1	Trehalose					150:158	Trehalose	150:158	Trehalose	150:158	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	1	69	theme	non-conventional	165:180	arg1	sugar					182:186	a non-conventional sugar	163:186	a non-conventional sugar with potent applications in the food, healthcare and biopharma industries	163:260	Trehalose is a non-conventional sugar with potent applications in the food, healthcare and biopharma industries.					
35791071	6	70	theme	byproduct	989:997	arg1	bioremoval					999:1008	byproduct bioremoval	989:1008	byproduct bioremoval	989:1008	A one-pot process integrating trehalose production and byproduct bioremoval showed 53.35% trehalose yield from 107.4 g/l after 15 h by permeabilized P. moteilii cells.					
35763904	2	0	theme	%	459:459	arg1	similarity					461:470	30% similarity	457:470	30% similarity between in vitro cultured and fecal samples	457:514	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	5	1	theme	fewer	1105:1109	arg1	effects					1116:1122	fewer side effects	1105:1122	fewer side effects	1105:1122	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	0	2	dep	in	107:108	arg1	vitro					110:114	vitro	110:114	vitro	110:114	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	3	3	dep	in	629:630	arg1	vitro					632:636	vitro	632:636	vitro	632:636	Baicalein and acarbose alone and in combination, and their corresponding starch hydrolysate were assayed by the in vitro model.					
35763904	2	4	theme	30	457:458	arg1	%					459:459	%	459:459	%	459:459	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	4	5	with	combination	676:686	arg1	acarbose					706:713	acarbose	706:713	acarbose	706:713	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	5	6	theme	dietary	1028:1034	arg1	supplements					1036:1046	flavonoid dietary supplements	1018:1046	flavonoid dietary supplements	1018:1046	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	1	7	theme	dietary	138:144	arg1	flavonoid-baicalein					146:164	dietary flavonoid-baicalein	138:164	dietary flavonoid-baicalein	138:164	Combination of dietary flavonoid-baicalein and acarbose reduces the risk that prediabetes will develop into type 2 diabetes mellitus; however, the mechanism underlying this effect has not been clarified.					
35763904	1	8	theme	diabetes	238:245	arg1	mellitus					247:254	type 2 diabetes mellitus	231:254	type 2 diabetes mellitus	231:254	Combination of dietary flavonoid-baicalein and acarbose reduces the risk that prediabetes will develop into type 2 diabetes mellitus; however, the mechanism underlying this effect has not been clarified.					
35763904	0	9	theme	gut	88:90	arg1	microbiota					92:101	gut microbiota	88:101	gut microbiota	88:101	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	2	10	from	mice	420:423	arg1	conditions					363:372	the in vitro culture conditions	342:372	the in vitro culture conditions of intestinal microorganisms from prediabetic mice	342:423	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	4	11	theme	gas	912:914	arg1	production					916:925	gas production	912:925	gas production	912:925	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	5	12	theme	oral	1075:1078	arg1	agents					1093:1098	oral hypoglycemic agents	1075:1098	oral hypoglycemic agents	1075:1098	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	2	13	theme	in	346:347	arg1	conditions					363:372	the in vitro culture conditions	342:372	the in vitro culture conditions of intestinal microorganisms from prediabetic mice	342:423	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	1	14	theme	flavonoid-baicalein	146:164	arg1	Combination					123:133	Combination	123:133	Combination of dietary flavonoid-baicalein and acarbose	123:177	Combination of dietary flavonoid-baicalein and acarbose reduces the risk that prediabetes will develop into type 2 diabetes mellitus; however, the mechanism underlying this effect has not been clarified.					
35763904	0	15	theme	microbiota	92:101	arg1	regulation					74:83	the regulation	70:83	the regulation of gut microbiota	70:101	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	5	16	theme	hypoglycemic	1080:1091	arg1	agents					1093:1098	oral hypoglycemic agents	1075:1098	oral hypoglycemic agents	1075:1098	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	5	17	theme	agents	1093:1098	arg1	efficacy					1063:1070	the efficacy	1059:1070	the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy	1059:1142	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	4	18	theme	acarbose	829:836	arg1	dosage					819:824	the dosage	815:824	the dosage of acarbose	815:836	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	1	19	theme	acarbose	170:177	arg1	Combination					123:133	Combination	123:133	Combination of dietary flavonoid-baicalein and acarbose	123:177	Combination of dietary flavonoid-baicalein and acarbose reduces the risk that prediabetes will develop into type 2 diabetes mellitus; however, the mechanism underlying this effect has not been clarified.					
35763904	5	20	theme	side	1111:1114	arg1	effects					1116:1122	fewer side effects	1105:1122	fewer side effects	1105:1122	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	2	21	theme	prediabetic	408:418	arg1	mice					420:423	prediabetic mice	408:423	prediabetic mice	408:423	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	0	22	theme	in	107:108	arg1	study					116:120	An in vitro study	104:120	An in vitro study	104:120	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	4	23	theme	gas	725:727	arg1	production					729:738	gas production	725:738	gas production	725:738	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	5	24	with	efficacy	1063:1070	arg1	efficacy					1135:1142	higher efficacy	1128:1142	higher efficacy	1128:1142	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	5	24	with	efficacy	1063:1070	arg1	effects					1116:1122	fewer side effects	1105:1122	fewer side effects	1105:1122	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	2	25	theme	microorganisms	388:401	arg1	conditions					363:372	the in vitro culture conditions	342:372	the in vitro culture conditions of intestinal microorganisms from prediabetic mice	342:423	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	0	26	theme	intestinal	13:22	arg1	effects					29:35	the intestinal side effects	9:35	the intestinal side effects of acarbose	9:47	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	4	27	theme	gut	883:885	arg1	bacteria					887:894	gut bacteria	883:894	gut bacteria correlated with gas production	883:925	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	2	28	theme	intestinal	377:386	arg1	microorganisms					388:401	intestinal microorganisms	377:401	intestinal microorganisms	377:401	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	5	29	theme	theoretical	972:982	arg1	foundation					984:993	a theoretical foundation	970:993	a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy	970:1142	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	2	30	theme	culture	355:361	arg1	conditions					363:372	the in vitro culture conditions	342:372	the in vitro culture conditions of intestinal microorganisms from prediabetic mice	342:423	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	2	31	theme	fecal	502:506	arg1	samples					508:514	fecal samples	502:514	fecal samples	502:514	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	0	32	theme	side	24:27	arg1	effects					29:35	the intestinal side effects	9:35	the intestinal side effects of acarbose	9:47	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	5	33	theme	higher	1128:1133	arg1	efficacy					1135:1142	higher efficacy	1128:1142	higher efficacy	1128:1142	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	4	34	theme	relative	861:868	arg1	abundance					870:878	the relative abundance	857:878	the relative abundance of gut bacteria correlated with gas production	857:925	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	0	35	theme	acarbose	40:47	arg1	effects					29:35	the intestinal side effects	9:35	the intestinal side effects of acarbose	9:47	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	4	36	theme	bacteria	887:894	arg1	abundance					870:878	the relative abundance	857:878	the relative abundance of gut bacteria correlated with gas production	857:925	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	5	37	theme	flavonoid	1018:1026	arg1	supplements					1036:1046	flavonoid dietary supplements	1018:1046	flavonoid dietary supplements	1018:1046	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	3	38	theme	corresponding	576:588	arg1	hydrolysate					597:607	their corresponding starch hydrolysate	570:607	their corresponding starch hydrolysate	570:607	Baicalein and acarbose alone and in combination, and their corresponding starch hydrolysate were assayed by the in vitro model.					
35763904	3	39	theme	starch	590:595	arg1	hydrolysate					597:607	their corresponding starch hydrolysate	570:607	their corresponding starch hydrolysate	570:607	Baicalein and acarbose alone and in combination, and their corresponding starch hydrolysate were assayed by the in vitro model.					
35763904	2	40	dep	in	346:347	arg1	vitro					349:353	vitro	349:353	vitro	349:353	In this study, the in vitro culture conditions of intestinal microorganisms from prediabetic mice were optimized to increase over 30% similarity between in vitro cultured and fecal samples.					
35763904	4	41	theme	starch	781:786	arg1	hydrolysate					788:798	starch hydrolysate	781:798	starch hydrolysate	781:798	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	4	42	theme	baicalein	691:699	arg1	combination					676:686	the combination	672:686	the combination of baicalein with acarbose	672:713	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	3	43	theme	in	629:630	arg1	model					638:642	the in vitro model	625:642	the in vitro model	625:642	Baicalein and acarbose alone and in combination, and their corresponding starch hydrolysate were assayed by the in vitro model.					
35763904	4	44	theme	residual	756:763	arg1	ratio					772:776	the residual starch ratio	752:776	the residual starch ratio in starch hydrolysate	752:798	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	4	45	theme	starch	765:770	arg1	ratio					772:776	the residual starch ratio	752:776	the residual starch ratio in starch hydrolysate	752:798	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	5	46	theme	supplements	1036:1046	arg1	development					1003:1013	the development	999:1013	the development of flavonoid dietary supplements	999:1046	This study provided a theoretical foundation for the development of flavonoid dietary supplements to enhance the efficacy of oral hypoglycemic agents with fewer side effects and higher efficacy.					
35763904	4	47	from	ratio	772:776	arg1	hydrolysate					788:798	starch hydrolysate	781:798	starch hydrolysate	781:798	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	4	48	theme	main	934:937	arg1	mechanism					939:947	the main mechanism	930:947	the main mechanism	930:947	The results indicated that the combination of baicalein with acarbose decreased gas production by reducing the residual starch ratio in starch hydrolysate and decreasing the dosage of acarbose, and that reducing the relative abundance of gut bacteria correlated with gas production is the main mechanism.					
35763904	0	49	dep	Reducing	0:7	arg1	study					116:120	An in vitro study	104:120	An in vitro study	104:120	Reducing the intestinal side effects of acarbose by baicalein through the regulation of gut microbiota: An in vitro study.					
35763904	1	50	theme	type	231:234	arg1	mellitus					247:254	type 2 diabetes mellitus	231:254	type 2 diabetes mellitus	231:254	Combination of dietary flavonoid-baicalein and acarbose reduces the risk that prediabetes will develop into type 2 diabetes mellitus; however, the mechanism underlying this effect has not been clarified.					
35715647	10	0	theme	genetic	1332:1338	arg1	basis					1340:1344	the genetic basis	1328:1344	the genetic basis of rice lipid content	1328:1366	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	1	1	theme	rice	105:108	arg1	content					120:126	rice crude fat content	105:126	rice crude fat content	105:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	10	2	theme	quality	1406:1412	arg1	improvement					1379:1389	the improvement	1375:1389	the improvement of rice eating quality	1375:1412	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	4	3	theme	lipids	312:317	arg1	content					319:325	The lipids content	308:325	The lipids content in rice	308:333	The lipids content in rice influences both storage and quality.					
35715647	1	4	theme	crude	110:114	arg1	content					120:126	rice crude fat content	105:126	rice crude fat content	105:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	8	5	theme	Lipid	744:748	arg1	composition					750:760	Lipid composition	744:760	Lipid composition	744:760	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	9	6	theme	content	982:988	arg1	varieties					995:1003	content rice varieties	982:1003	content rice varieties	982:1003	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	3	7	theme	major	272:276	arg1	lipids					251:256	lipids	251:256	lipids	251:256	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	3	7	theme	major	272:276	arg1	protein					239:245	protein	239:245	protein	239:245	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	3	7	theme	major	272:276	arg1	Starch					231:236	Starch	231:236	Starch	231:236	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	3	7	theme	major	272:276	arg1	components					278:287	the three major components	262:287	the three major components in rice endosperm	262:305	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	8	8	theme	bound	873:877	arg1	lipids					879:884	bound lipids	873:884	bound lipids content	873:892	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	2	9	theme	rice	217:220	arg1	quality					222:228	rice quality	217:228	rice quality	217:228	FC6 negatively regulates crude fat content and rice quality.					
35715647	9	10	theme	higher	963:968	arg1	lipids					975:980	higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking	963:1089	higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking	963:1089	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	10	11	theme	fat	1270:1272	arg1	content					1274:1280	rice crude fat content	1259:1280	rice crude fat content	1259:1280	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	4	12	from	content	319:325	arg1	rice					330:333	rice	330:333	rice	330:333	The lipids content in rice influences both storage and quality.					
35715647	8	13	theme	lipids	879:884	arg1	content					886:892	bound lipids content	873:892	bound lipids content	873:892	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	8	14	theme	content	766:772	arg1	analysis					774:781	content analysis	766:781	content analysis	766:781	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	9	15	theme	free	970:973	arg1	lipids					975:980	higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking	963:1089	higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking	963:1089	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	5	16	theme	association	485:495	arg1	analysis					497:504	association analysis	485:504	association analysis	485:504	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	10	17	theme	crude	1264:1268	arg1	content					1274:1280	rice crude fat content	1259:1280	rice crude fat content	1259:1280	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	1	18	theme	fat	116:118	arg1	content					120:126	rice crude fat content	105:126	rice crude fat content	105:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	8	19	dep	lipids	928:933	arg1	lipids					928:933	both free lipids content and taste	918:951	both free lipids content and taste	918:951	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	8	19	dep	lipids	928:933	arg1	taste					947:951	taste	947:951	taste	947:951	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	8	19	dep	lipids	928:933	arg1	content					935:941	content	935:941	content	935:941	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	10	20	theme	rice	1349:1352	arg1	content					1360:1366	rice lipid content	1349:1366	rice lipid content	1349:1366	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	5	21	theme	crude	445:449	arg1	fat					451:453	crude fat	445:453	crude fat (free lipids) content	445:475	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	21	theme	crude	445:449	arg1	lipids					461:466	free lipids	456:466	free lipids	456:466	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	2	22	theme	fat	201:203	arg1	content					205:211	crude fat content	195:211	crude fat content	195:211	FC6 negatively regulates crude fat content and rice quality.					
35715647	5	23	theme	quantitative	403:414	arg1	QTL					429:431	QTL	429:431	QTL	429:431	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	23	theme	quantitative	403:414	arg1	qFC6					435:438	qFC6	435:438	qFC6	435:438	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	23	theme	quantitative	403:414	arg1	locus					422:426	a quantitative trait locus	401:426	a quantitative trait locus (QTL)	401:432	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	0	24	from	gene	14:17	arg1	rice					56:59	rice	56:59	rice	56:59	qFC6, a major gene for crude fat content and quality in rice.					
35715647	5	25	theme	fat	451:453	arg1	content					469:475	crude fat (free lipids) content	445:475	crude fat (free lipids) content	445:475	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	26	theme	trait	416:420	arg1	QTL					429:431	QTL	429:431	QTL	429:431	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	26	theme	trait	416:420	arg1	qFC6					435:438	qFC6	435:438	qFC6	435:438	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	26	theme	trait	416:420	arg1	locus					422:426	a quantitative trait locus	401:426	a quantitative trait locus (QTL)	401:432	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	10	27	dep	QTL	1242:1244	arg1	coordinating					1246:1257	coordinating	1246:1257	coordinating rice crude fat content	1246:1280	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	10	27	dep	QTL	1242:1244	arg1	eating					1286:1291	eating	1286:1291	eating quality	1286:1299	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	10	27	dep	QTL	1242:1244	arg1	assisted					1305:1312	assisted	1305:1312	assisted	1305:1312	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	5	28	theme	linkage	510:516	arg1	analysis					518:525	linkage analysis	510:525	linkage analysis	510:525	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	8	29	theme	free	923:926	arg1	lipids					928:933	both free lipids content and taste	918:951	both free lipids content and taste	918:951	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	8	29	theme	free	923:926	arg1	taste					947:951	taste	947:951	taste	947:951	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	8	29	theme	free	923:926	arg1	content					935:941	content	935:941	content	935:941	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	10	30	theme	lipid	1354:1358	arg1	content					1360:1366	rice lipid content	1349:1366	rice lipid content	1349:1366	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	8	31	theme	gas	786:788	arg1	chromatography					790:803	gas chromatography	786:803	gas chromatography	786:803	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	0	32	theme	major	8:12	arg1	qFC6					0:3	qFC6	0:3	qFC6	0:3	qFC6, a major gene for crude fat content and quality in rice.					
35715647	0	32	theme	major	8:12	arg1	gene					14:17	a major gene	6:17	a major gene for crude fat content and quality in rice	6:59	qFC6, a major gene for crude fat content and quality in rice.					
35715647	5	33	theme	free	456:459	arg1	fat					451:453	crude fat	445:453	crude fat (free lipids) content	445:475	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	5	33	theme	free	456:459	arg1	lipids					461:466	free lipids	456:466	free lipids	456:466	In this study, we identified a quantitative trait locus (QTL), qFC6, for crude fat (free lipids) content through association analysis and linkage analysis.					
35715647	7	34	theme	crude	725:729	arg1	content					735:741	crude fat content	725:741	crude fat content	725:741	Complementation and knockout transgenic lines revealed that Wx negatively regulates crude fat content.					
35715647	3	35	theme	rice	292:295	arg1	endosperm					297:305	rice endosperm	292:305	rice endosperm	292:305	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	7	36	theme	transgenic	670:679	arg1	lines					681:685	knockout transgenic lines	661:685	knockout transgenic lines	661:685	Complementation and knockout transgenic lines revealed that Wx negatively regulates crude fat content.					
35715647	9	37	theme	lustrous	1018:1025	arg1	appearance					1027:1036	more lustrous appearance	1013:1036	more lustrous appearance	1013:1036	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	9	38	theme	rice	990:993	arg1	varieties					995:1003	content rice varieties	982:1003	content rice varieties	982:1003	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	10	39	theme	content	1360:1366	arg1	basis					1340:1344	the genetic basis	1328:1344	the genetic basis of rice lipid content	1328:1366	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	8	40	theme	evaluation	815:824	arg1	analysis					826:833	taste evaluation analysis	809:833	taste evaluation analysis	809:833	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	0	41	theme	fat	29:31	arg1	content					33:39	crude fat content	23:39	crude fat content	23:39	qFC6, a major gene for crude fat content and quality in rice.					
35715647	7	42	theme	knockout	661:668	arg1	lines					681:685	knockout transgenic lines	661:685	knockout transgenic lines	661:685	Complementation and knockout transgenic lines revealed that Wx negatively regulates crude fat content.					
35715647	10	43	theme	eating	1399:1404	arg1	quality					1406:1412	rice eating quality	1394:1412	rice eating quality	1394:1412	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	3	44	from	components	278:287	arg1	endosperm					297:305	rice endosperm	292:305	rice endosperm	292:305	Starch, protein and lipids are the three major components in rice endosperm.					
35715647	8	45	theme	taste	809:813	arg1	analysis					826:833	taste evaluation analysis	809:833	taste evaluation analysis	809:833	Lipid composition and content analysis by gas chromatography and taste evaluation analysis showed that FC6 positively influenced bound lipids content and negatively affected both free lipids content and taste.					
35715647	0	46	theme	crude	23:27	arg1	content					33:39	crude fat content	23:39	crude fat content	23:39	qFC6, a major gene for crude fat content and quality in rice.					
35715647	10	47	theme	rice	1394:1397	arg1	quality					1406:1412	rice eating quality	1394:1412	rice eating quality	1394:1412	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	9	48	theme	higher	1150:1155	arg1	content					1169:1175	higher free lipids content	1150:1175	higher free lipids content	1150:1175	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	9	49	theme	free	1157:1160	arg1	content					1169:1175	higher free lipids content	1150:1175	higher free lipids content	1150:1175	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	1	50	theme	major	70:74	arg1	qFC6					62:65	qFC6	62:65	qFC6	62:65	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	1	50	theme	major	70:74	arg1	locus					95:99	a major quantitative trait locus	68:99	a major quantitative trait locus for rice crude fat content	68:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	6	51	theme	association	539:549	arg1	analysis					551:558	Gene-based association analysis	528:558	Gene-based association analysis	528:558	Gene-based association analysis revealed that LOC_Os06g04200, also known as Wx, was the candidate gene for qFC6.					
35715647	9	52	theme	taste	1121:1125	arg1	score					1127:1131	taste score	1121:1131	taste score	1121:1131	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	9	53	theme	rice	1105:1108	arg1	luster					1110:1115	rice luster	1105:1115	rice luster	1105:1115	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	2	54	theme	crude	195:199	arg1	content					205:211	crude fat content	195:211	crude fat content	195:211	FC6 negatively regulates crude fat content and rice quality.					
35715647	6	55	theme	candidate	616:624	arg1	gene					626:629	the candidate gene	612:629	the candidate gene for qFC6	612:638	Gene-based association analysis revealed that LOC_Os06g04200, also known as Wx, was the candidate gene for qFC6.					
35715647	6	55	theme	candidate	616:624	arg1	LOC_Os06g04200					574:587	LOC_Os06g04200	574:587	LOC_Os06g04200	574:587	Gene-based association analysis revealed that LOC_Os06g04200, also known as Wx, was the candidate gene for qFC6.					
35715647	1	56	theme	quantitative	76:87	arg1	qFC6					62:65	qFC6	62:65	qFC6	62:65	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	1	56	theme	quantitative	76:87	arg1	locus					95:99	a major quantitative trait locus	68:99	a major quantitative trait locus for rice crude fat content	68:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	6	57	theme	Gene-based	528:537	arg1	analysis					551:558	Gene-based association analysis	528:558	Gene-based association analysis	528:558	Gene-based association analysis revealed that LOC_Os06g04200, also known as Wx, was the candidate gene for qFC6.					
35715647	9	58	dep	lipids	975:980	arg1	exhibit					1005:1011	exhibit	1005:1011	exhibit more lustrous appearance after cooking and by adding extra oil during cooking	1005:1089	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	9	59	theme	lipids	1162:1167	arg1	content					1169:1175	higher free lipids content	1150:1175	higher free lipids content	1150:1175	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	9	60	theme	extra	1066:1070	arg1	oil					1072:1074	extra oil	1066:1074	extra oil	1066:1074	Besides, higher free lipids content rice varieties exhibit more lustrous appearance after cooking and by adding extra oil during cooking could improve rice luster and taste score, indicating that higher free lipids content may make rice more lustrous and delicious.					
35715647	10	61	theme	rice	1259:1262	arg1	content					1274:1280	rice crude fat content	1259:1280	rice crude fat content	1259:1280	Together, we cloned a QTL coordinating rice crude fat content and eating quality and assisted in uncovering the genetic basis of rice lipid content and in the improvement of rice eating quality.					
35715647	1	62	theme	trait	89:93	arg1	qFC6					62:65	qFC6	62:65	qFC6	62:65	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	1	62	theme	trait	89:93	arg1	locus					95:99	a major quantitative trait locus	68:99	a major quantitative trait locus for rice crude fat content	68:126	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	7	63	theme	fat	731:733	arg1	content					735:741	crude fat content	725:741	crude fat content	725:741	Complementation and knockout transgenic lines revealed that Wx negatively regulates crude fat content.					
35715647	1	64	dep	mapped	138:143	arg1	fine					133:136	fine	133:136	fine	133:136	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
35715647	1	65	with	identical	151:159	arg1	Wx					166:167	Wx	166:167	Wx	166:167	qFC6, a major quantitative trait locus for rice crude fat content, was fine mapped to be identical with Wx.					
36724073	3	0	theme	tetraspanin	369:379	arg1	trafficking					381:391	tetraspanin trafficking	369:391	tetraspanin trafficking	369:391	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	6	1	theme	multiple	1011:1018	arg1	enzymes					1037:1043	multiple glycan-modifying enzymes	1011:1043	multiple glycan-modifying enzymes	1011:1043	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	4	2	theme	endoplasmic	569:579	arg1	ER					592:593	ER	592:593	ER	592:593	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	4	2	theme	endoplasmic	569:579	arg1	reticulum					581:589	endoplasmic reticulum	569:589	endoplasmic reticulum (ER) targeting	569:604	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	1	3	theme	biological	176:185	arg1	processes					187:195	diverse biological processes	168:195	diverse biological processes	168:195	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	6	4	theme	lacto-series	1127:1138	arg1	biosynthesis					1151:1162	lacto-series glycolipid biosynthesis	1127:1162	lacto-series glycolipid biosynthesis	1127:1162	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	0	5	theme	tetraspanins	96:107	arg1	expression					82:91	cell-surface expression	69:91	cell-surface expression of tetraspanins	69:107	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.					
36724073	3	6	theme	genome-wide	416:426	arg1	screens					457:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens	405:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8	405:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	7	7	theme	tetraspanins	1264:1275	arg1	presentation					1248:1259	cell-surface presentation	1235:1259	cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion	1235:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	3	8	theme	loss-of-function	428:443	arg1	screens					457:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens	405:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8	405:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	5	9	theme	biantennary	755:765	arg1	N-glycans					767:775	biantennary N-glycans	755:775	biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures,	755:837	Importantly, we find that biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures, are important for cell-surface tetraspanin expression.					
36724073	4	10	theme	protein	666:672	arg1	trafficking					674:684	protein trafficking	666:684	protein trafficking	666:684	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	5	11	theme	cell-surface	857:868	arg1	expression					882:891	cell-surface tetraspanin expression	857:891	cell-surface tetraspanin expression	857:891	Importantly, we find that biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures, are important for cell-surface tetraspanin expression.					
36724073	7	12	theme	presentation	1248:1259	arg1	regulation					1221:1230	the molecular regulation	1207:1230	the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion	1207:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	3	13	theme	sequential	405:414	arg1	screens					457:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens	405:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8	405:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	4	14	theme	reticulum	581:589	arg1	processes					628:636	different biological processes	607:636	different biological processes in the Golgi apparatus	607:659	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	4	14	theme	reticulum	581:589	arg1	targeting					596:604	endoplasmic reticulum (ER) targeting	569:604	endoplasmic reticulum (ER) targeting	569:604	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	5	15	theme	tetraspanin	870:880	arg1	expression					882:891	cell-surface tetraspanin expression	857:891	cell-surface tetraspanin expression	857:891	Importantly, we find that biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures, are important for cell-surface tetraspanin expression.					
36724073	7	16	theme	cancer	1351:1356	arg1	invasion					1363:1370	cancer cell invasion	1351:1370	cancer cell invasion	1351:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	1	17	theme	tetraspanin-enriched	205:224	arg1	microdomains					226:237	tetraspanin-enriched microdomains	205:237	tetraspanin-enriched microdomains in the plasma membrane	205:260	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	0	18	theme	genome-wide	11:21	arg1	screens					35:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.					
36724073	3	19	theme	trafficking	381:391	arg1	regulators					355:364	the regulators	351:364	the regulators of tetraspanin trafficking	351:391	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	3	20	theme	tetraspanin	503:513	arg1	TSPAN8					523:528	TSPAN8	523:528	TSPAN8	523:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	3	20	theme	tetraspanin	503:513	arg1	member					515:520	a tetraspanin member	501:520	a tetraspanin member	501:520	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	0	21	theme	Sequential	0:9	arg1	screens					35:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.					
36724073	7	22	theme	cell-surface	1235:1246	arg1	presentation					1248:1259	cell-surface presentation	1235:1259	cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion	1235:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	7	23	dep	strategies	1299:1308	arg1	manipulate					1313:1322	manipulate	1313:1322	to manipulate their functions	1310:1338	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	3	24	theme	member	515:520	arg1	expression					487:496	cell-surface expression	474:496	cell-surface expression of a tetraspanin member, TSPAN8	474:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	3	25	theme	CRISPR-Cas9	445:455	arg1	screens					457:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens	405:463	sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8	405:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	7	26	theme	molecular	1211:1219	arg1	regulation					1221:1230	the molecular regulation	1207:1230	the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion	1207:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	0	27	theme	CRISPR-Cas9	23:33	arg1	screens					35:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens	0:41	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.					
36724073	4	28	theme	Several	531:537	arg1	genes					539:543	Several genes	531:543	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking	531:684	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	1	29	theme	plasma	246:251	arg1	membrane					253:260	the plasma membrane	242:260	the plasma membrane	242:260	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	4	30	from	processes	628:636	arg1	apparatus					651:659	the Golgi apparatus	641:659	the Golgi apparatus	641:659	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	4	31	theme	Golgi	645:649	arg1	apparatus					651:659	the Golgi apparatus	641:659	the Golgi apparatus	641:659	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	7	32	theme	cell	1358:1361	arg1	invasion					1363:1370	cancer cell invasion	1351:1370	cancer cell invasion	1351:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	6	33	theme	tetraspanin	1068:1078	arg1	expression					1080:1089	cell-surface tetraspanin expression	1055:1089	cell-surface tetraspanin expression	1055:1089	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	4	34	theme	different	607:615	arg1	processes					628:636	different biological processes	607:636	different biological processes in the Golgi apparatus	607:659	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	4	34	theme	different	607:615	arg1	targeting					596:604	endoplasmic reticulum (ER) targeting	569:604	endoplasmic reticulum (ER) targeting	569:604	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	6	35	theme	glycolipid	1140:1149	arg1	biosynthesis					1151:1162	lacto-series glycolipid biosynthesis	1127:1162	lacto-series glycolipid biosynthesis	1127:1162	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	6	36	theme	enzymes	1037:1043	arg1	sheddase					999:1006	a sheddase	997:1006	a sheddase of multiple glycan-modifying enzymes	997:1043	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	0	37	theme	cell-surface	69:80	arg1	expression					82:91	cell-surface expression	69:91	cell-surface expression of tetraspanins	69:107	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.					
36724073	5	38	theme	complex	812:818	arg1	structures					827:836	more complex glycan structures	807:836	more complex glycan structures	807:836	Importantly, we find that biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures, are important for cell-surface tetraspanin expression.					
36724073	7	39	theme	critical	1184:1191	arg1	insights					1193:1200	critical insights	1184:1200	critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion	1184:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	6	40	theme	intramembrane-cleaving	935:956	arg1	protease					958:965	a Golgi intramembrane-cleaving protease	927:965	a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes	927:1043	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	6	40	theme	intramembrane-cleaving	935:956	arg1	SPPL3					920:924	SPPL3	920:924	SPPL3	920:924	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	6	41	theme	Golgi	929:933	arg1	protease					958:965	a Golgi intramembrane-cleaving protease	927:965	a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes	927:1043	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	6	41	theme	Golgi	929:933	arg1	SPPL3					920:924	SPPL3	920:924	SPPL3	920:924	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	1	42	theme	membrane	141:148	arg1	proteins					150:157	membrane proteins	141:157	membrane proteins	141:157	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	4	43	theme	biological	617:626	arg1	processes					628:636	different biological processes	607:636	different biological processes in the Golgi apparatus	607:659	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	4	43	theme	biological	617:626	arg1	targeting					596:604	endoplasmic reticulum (ER) targeting	569:604	endoplasmic reticulum (ER) targeting	569:604	Several genes potentially involved in endoplasmic reticulum (ER) targeting, different biological processes in the Golgi apparatus, and protein trafficking are identified and functionally validated.					
36724073	6	44	theme	cell-surface	1055:1066	arg1	expression					1080:1089	cell-surface tetraspanin expression	1055:1089	cell-surface tetraspanin expression	1055:1089	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	1	45	theme	proteins	150:157	arg1	Tetraspanins					110:121	Tetraspanins	110:121	Tetraspanins	110:121	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	1	45	theme	proteins	150:157	arg1	superfamily					126:136	a superfamily	124:136	a superfamily of membrane proteins	124:157	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	1	46	from	microdomains	226:237	arg1	membrane					253:260	the plasma membrane	242:260	the plasma membrane	242:260	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	7	47	with	tetraspanins	1264:1275	arg1	implications					1282:1293	implications	1282:1293	implications	1282:1293	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	7	47	with	tetraspanins	1264:1275	arg1	invasion					1363:1370	cancer cell invasion	1351:1370	cancer cell invasion	1351:1370	Our study provides critical insights into the molecular regulation of cell-surface presentation of tetraspanins with implications for strategies to manipulate their functions, including cancer cell invasion.					
36724073	3	48	theme	cell-surface	474:485	arg1	expression					487:496	cell-surface expression	474:496	cell-surface expression of a tetraspanin member, TSPAN8	474:528	To identify the regulators of tetraspanin trafficking, we conduct sequential genome-wide loss-of-function CRISPR-Cas9 screens based on cell-surface expression of a tetraspanin member, TSPAN8.					
36724073	6	49	theme	glycan-modifying	1020:1035	arg1	enzymes					1037:1043	multiple glycan-modifying enzymes	1011:1043	multiple glycan-modifying enzymes	1011:1043	Moreover, we unravel that SPPL3, a Golgi intramembrane-cleaving protease reported previously to act as a sheddase of multiple glycan-modifying enzymes, controls cell-surface tetraspanin expression through a mechanism associated with lacto-series glycolipid biosynthesis.					
36724073	2	50	theme	cell-surface	282:293	arg1	presentation					295:306	their cell-surface presentation	276:306	their cell-surface presentation	276:306	However, how their cell-surface presentation is controlled remains unclear.					
36724073	1	51	theme	diverse	168:174	arg1	processes					187:195	diverse biological processes	168:195	diverse biological processes	168:195	Tetraspanins, a superfamily of membrane proteins, mediate diverse biological processes through tetraspanin-enriched microdomains in the plasma membrane.					
36724073	5	52	theme	glycan	820:825	arg1	structures					827:836	more complex glycan structures	807:836	more complex glycan structures	807:836	Importantly, we find that biantennary N-glycans generated by MGAT1/2, but not more complex glycan structures, are important for cell-surface tetraspanin expression.					
36674448	5	0	theme	corneal	702:708	arg1	wound					730:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound was created, and wound closure was monitored.					
36674448	1	1	theme	nerve	176:180	arg1	function					182:189	corneal nerve function	168:189	corneal nerve function	168:189	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	9	2	theme	platelet	1290:1297	arg1	influx					1299:1304	neutrophil and platelet influx	1275:1304	neutrophil and platelet influx	1275:1304	Diet restored normal wound closure and neutrophil and platelet influx in the injured cornea.					
36674448	0	3	theme	Corneal	92:98	arg1	Dysregulation					100:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	1	4	theme	function	182:189	arg1	loss					160:163	loss	160:163	loss of corneal nerve function	160:189	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	2	5	from	reduction	339:347	arg1	function					358:365	nerve function	352:365	nerve function	352:365	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	10	6	dep	suggest	1340:1346	arg1	strategy					1425:1432	an effective diet-based therapeutic strategy	1389:1432	an effective diet-based therapeutic strategy for maintaining or restoring corneal health	1389:1476	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
36674448	2	7	theme	complex	303:309	arg1	carbohydrates					311:323	complex carbohydrates	303:323	complex carbohydrates	303:323	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	8	8	theme	≤	1081:1081	arg1	p					1079:1079	p ≤ 0.01	1079:1086	p ≤ 0.01	1079:1086	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	8	theme	≤	1081:1081	arg1	h					1076:1076	~6 h	1073:1076	~6 h (p ≤ 0.01)	1073:1087	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	9	theme	corneal	1026:1032	arg1	abrasion					1034:1041	corneal abrasion	1026:1041	corneal abrasion	1026:1041	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	3	10	theme	high-fat/sucrose	521:536	arg1	diet					538:541	a high-fat/sucrose diet	519:541	a high-fat/sucrose diet	519:541	In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks.					
36674448	3	11	theme	male	476:479	arg1	mice					481:484	6-week-old C57BL/6 male mice	457:484	6-week-old C57BL/6 male mice	457:484	In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks.					
36674448	0	12	from	Carbohydrates	39:51	arg1	Rich					23:26	Rich	23:26	Rich	23:26	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	8	13	theme	~6	1073:1074	arg1	p					1079:1079	p ≤ 0.01	1079:1086	p ≤ 0.01	1079:1086	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	13	theme	~6	1073:1074	arg1	h					1076:1076	~6 h	1073:1076	~6 h (p ≤ 0.01)	1073:1087	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	9	14	theme	injured	1313:1319	arg1	cornea					1321:1326	the injured cornea	1309:1326	the injured cornea	1309:1326	Diet restored normal wound closure and neutrophil and platelet influx in the injured cornea.					
36674448	4	15	theme	third	559:563	arg1	group					565:569	A third group	557:569	A third group (diet reversal)	557:585	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	4	15	theme	third	559:563	arg1	reversal					577:584	diet reversal	572:584	diet reversal	572:584	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	5	16	theme	abrasion	721:728	arg1	wound					730:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound was created, and wound closure was monitored.					
36674448	4	17	theme	high-fat/sucrose	603:618	arg1	diet					620:623	a high-fat/sucrose diet	601:623	a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks	601:689	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	0	18	theme	Low-Fat/Sucrose	2:16	arg1	Diet					18:21	A Low-Fat/Sucrose Diet	0:21	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates	0:51	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	5	19	theme	epithelial	710:719	arg1	wound					730:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound was created, and wound closure was monitored.					
36674448	7	20	theme	greater	909:915	arg1	p					928:928	p	928:928	p &lt; 0.005	928:939	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	7	20	theme	greater	909:915	arg1	adiposity					917:925	greater adiposity	909:925	greater adiposity (p &lt; 0.005) than normal diet-only fed mice	909:971	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	6	21	theme	immunofluorescence	834:851	arg1	microscopy					853:862	immunofluorescence microscopy	834:862	immunofluorescence microscopy	834:862	Neutrophil and platelet recruitment was assessed by immunofluorescence microscopy.					
36674448	1	22	theme	corneal	203:209	arg1	healing					217:223	corneal wound healing	203:223	corneal wound healing	203:223	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	7	23	theme	high-fat/sucrose	878:893	arg1	diet-only					895:903	the high-fat/sucrose diet-only	874:903	the high-fat/sucrose diet-only	874:903	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	1	24	theme	High-fat/sucrose	115:130	arg1	feeding					137:143	High-fat/sucrose diet feeding	115:143	High-fat/sucrose diet feeding in mice	115:151	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	1	25	theme	wound	211:215	arg1	healing					217:223	corneal wound healing	203:223	corneal wound healing	203:223	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	0	26	theme	Rich	23:26	arg1	Diet					18:21	A Low-Fat/Sucrose Diet	0:21	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates	0:51	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	4	27	theme	additional	671:680	arg1	weeks					685:689	an additional 10 weeks	668:689	an additional 10 weeks	668:689	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	8	28	from	limbus	1214:1219	arg1	present					1199:1205	present	1199:1205	present	1199:1205	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	1	29	theme	diet	132:135	arg1	feeding					137:143	High-fat/sucrose diet feeding	115:143	High-fat/sucrose diet feeding in mice	115:151	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	2	30	theme	corneal	419:425	arg1	healing					433:439	corneal wound healing	419:439	corneal wound healing	419:439	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	2	31	theme	wound	427:431	arg1	healing					433:439	corneal wound healing	419:439	corneal wound healing	419:439	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	8	32	attach	present	1199:1205	arg2	platelets					1184:1192	fewer extravascular platelets	1164:1192	fewer extravascular platelets	1164:1192	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	32	attach	present	1199:1205	arg2	neutrophils					1123:1133	fewer neutrophils	1117:1133	fewer neutrophils reached the wound center	1117:1158	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	32	attach	present	1199:1205	arg1	h					1100:1100	30 h post-wounding	1097:1114	30 h post-wounding	1097:1114	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	32	attach	present	1199:1205	arg1	p					1222:1222	p	1222:1222	p &lt; 0.05	1222:1232	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	32	attach	present	1199:1205	arg1	limbus					1214:1219	the limbus	1210:1219	the limbus (p &lt; 0.05)	1210:1233	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	2	33	from	composition	272:282	arg1	carbohydrates					311:323	complex carbohydrates	303:323	complex carbohydrates	303:323	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	3	34	theme	6-week-old	457:466	arg1	mice					481:484	6-week-old C57BL/6 male mice	457:484	6-week-old C57BL/6 male mice	457:484	In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks.					
36674448	0	35	theme	Complex	31:37	arg1	Carbohydrates					39:51	Complex Carbohydrates	31:51	Complex Carbohydrates	31:51	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	2	36	with	diet	246:249	arg1	enrichments					288:298	enrichments	288:298	enrichments in complex carbohydrates	288:323	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	2	36	with	diet	246:249	arg1	composition					272:282	a low fat/sugar composition	256:282	a low fat/sugar composition	256:282	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	8	37	theme	wound	1044:1048	arg1	closure					1050:1056	wound closure	1044:1056	wound closure	1044:1056	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	38	located	present	1199:1205	arg2	platelets					1184:1192	fewer extravascular platelets	1164:1192	fewer extravascular platelets	1164:1192	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	38	located	present	1199:1205	arg2	neutrophils					1123:1133	fewer neutrophils	1117:1133	fewer neutrophils reached the wound center	1117:1158	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	38	located	present	1199:1205	arg1	h					1100:1100	30 h post-wounding	1097:1114	30 h post-wounding	1097:1114	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	38	located	present	1199:1205	arg1	p					1222:1222	p	1222:1222	p &lt; 0.05	1222:1232	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	38	located	present	1199:1205	arg1	limbus					1214:1219	the limbus	1210:1219	the limbus (p &lt; 0.05)	1210:1233	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	39	theme	wound	1147:1151	arg1	center					1153:1158	the wound center	1143:1158	the wound center	1143:1158	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	8	40	theme	post-wounding	1102:1114	arg1	h					1100:1100	30 h post-wounding	1097:1114	30 h post-wounding	1097:1114	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	6	41	theme	platelet	797:804	arg1	recruitment					806:816	Neutrophil and platelet recruitment	782:816	Neutrophil and platelet recruitment	782:816	Neutrophil and platelet recruitment was assessed by immunofluorescence microscopy.					
36674448	5	42	theme	wound	753:757	arg1	closure					759:765	wound closure	753:765	wound closure	753:765	A central corneal epithelial abrasion wound was created, and wound closure was monitored.					
36674448	7	43	theme	fed	964:966	arg1	mice					968:971	normal diet-only fed mice	947:971	normal diet-only fed mice	947:971	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	8	44	theme	extravascular	1170:1182	arg1	platelets					1184:1192	fewer extravascular platelets	1164:1192	fewer extravascular platelets	1164:1192	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	10	45	theme	diet-based	1402:1411	arg1	strategy					1425:1432	an effective diet-based therapeutic strategy	1389:1432	an effective diet-based therapeutic strategy for maintaining or restoring corneal health	1389:1476	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
36674448	2	46	contain	has	402:404	arg1	it					399:400	it	399:400	it	399:400	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	2	46	contain	has	402:404	arg2	effect					409:414	an effect	406:414	an effect on corneal wound healing	406:439	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	10	47	theme	effective	1392:1400	arg1	strategy					1425:1432	an effective diet-based therapeutic strategy	1389:1432	an effective diet-based therapeutic strategy for maintaining or restoring corneal health	1389:1476	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
36674448	8	48	theme	fewer	1117:1121	arg1	neutrophils					1123:1133	fewer neutrophils	1117:1133	fewer neutrophils reached the wound center	1117:1158	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	9	49	theme	normal	1250:1255	arg1	closure					1263:1269	normal wound closure	1250:1269	normal wound closure	1250:1269	Diet restored normal wound closure and neutrophil and platelet influx in the injured cornea.					
36674448	8	50	from	h	1100:1100	arg1	present					1199:1205	present	1199:1205	present	1199:1205	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	6	51	theme	Neutrophil	782:791	arg1	recruitment					806:816	Neutrophil and platelet recruitment	782:816	Neutrophil and platelet recruitment	782:816	Neutrophil and platelet recruitment was assessed by immunofluorescence microscopy.					
36674448	10	52	theme	compositional	1348:1360	arg1	changes					1362:1368	compositional changes	1348:1368	compositional changes to the diet	1348:1380	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
36674448	7	53	theme	normal	947:952	arg1	mice					968:971	normal diet-only fed mice	947:971	normal diet-only fed mice	947:971	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	4	54	theme	normal	652:657	arg1	diet					659:662	a normal diet	650:662	a normal diet for an additional 10 weeks	650:689	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	2	55	from	enrichments	288:298	arg1	carbohydrates					311:323	complex carbohydrates	303:323	complex carbohydrates	303:323	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	9	56	theme	wound	1257:1261	arg1	closure					1263:1269	normal wound closure	1250:1269	normal wound closure	1250:1269	Diet restored normal wound closure and neutrophil and platelet influx in the injured cornea.					
36674448	5	57	theme	central	694:700	arg1	wound					730:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound	692:734	A central corneal epithelial abrasion wound was created, and wound closure was monitored.					
36674448	2	58	theme	nerve	352:356	arg1	function					358:365	nerve function	352:365	nerve function	352:365	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	1	59	from	feeding	137:143	arg1	mice					148:151	mice	148:151	mice	148:151	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	4	60	theme	diet	572:575	arg1	group					565:569	A third group	557:569	A third group (diet reversal)	557:585	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	4	60	theme	diet	572:575	arg1	reversal					577:584	diet reversal	572:584	diet reversal	572:584	A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks.					
36674448	7	61	theme	diet	974:977	arg1	reversal					979:986	diet reversal	974:986	diet reversal	974:986	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	2	62	theme	fat/sugar	262:270	arg1	composition					272:282	a low fat/sugar composition	256:282	a low fat/sugar composition	256:282	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	2	63	from	effect	409:414	arg1	healing					433:439	corneal wound healing	419:439	corneal wound healing	419:439	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	3	64	theme	normal	504:509	arg1	diet					511:514	a normal diet	502:514	a normal diet	502:514	In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks.					
36674448	3	65	theme	C57BL/6	468:474	arg1	mice					481:484	6-week-old C57BL/6 male mice	457:484	6-week-old C57BL/6 male mice	457:484	In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks.					
36674448	0	66	theme	Diet-Induced	79:90	arg1	Dysregulation					100:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	7	67	theme	diet-only	954:962	arg1	mice					968:971	normal diet-only fed mice	947:971	normal diet-only fed mice	947:971	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	2	68	theme	low	258:260	arg1	composition					272:282	a low fat/sugar composition	256:282	a low fat/sugar composition	256:282	While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing.					
36674448	8	69	theme	fewer	1164:1168	arg1	platelets					1184:1192	fewer extravascular platelets	1164:1192	fewer extravascular platelets	1164:1192	Following corneal abrasion, wound closure was delayed by ~6 h (p ≤ 0.01) and, at 30 h post-wounding, fewer neutrophils reached the wound center and fewer extravascular platelets were present at the limbus (p &lt; 0.05).					
36674448	10	70	theme	therapeutic	1413:1423	arg1	strategy					1425:1432	an effective diet-based therapeutic strategy	1389:1432	an effective diet-based therapeutic strategy for maintaining or restoring corneal health	1389:1476	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
36674448	9	71	theme	neutrophil	1275:1284	arg1	influx					1299:1304	neutrophil and platelet influx	1275:1304	neutrophil and platelet influx	1275:1304	Diet restored normal wound closure and neutrophil and platelet influx in the injured cornea.					
36674448	0	72	theme	High-Fat/Sucrose	62:77	arg1	Dysregulation					100:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	High-Fat/Sucrose Diet-Induced Corneal Dysregulation	62:112	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	0	73	from	Rich	23:26	arg1	Carbohydrates					39:51	Complex Carbohydrates	31:51	Complex Carbohydrates	31:51	A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.					
36674448	7	74	contain	had	905:907	arg1	Mice					865:868	Mice	865:868	Mice fed the high-fat/sucrose diet-only	865:903	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	7	74	contain	had	905:907	arg2	p					928:928	p	928:928	p &lt; 0.005	928:939	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	7	74	contain	had	905:907	arg2	adiposity					917:925	greater adiposity	909:925	greater adiposity (p &lt; 0.005) than normal diet-only fed mice	909:971	Mice fed the high-fat/sucrose diet-only had greater adiposity (p &lt; 0.005) than normal diet-only fed mice; diet reversal markedly reduced adiposity.					
36674448	1	75	theme	corneal	168:174	arg1	function					182:189	corneal nerve function	168:189	corneal nerve function	168:189	High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing.					
36674448	10	76	theme	corneal	1463:1469	arg1	health					1471:1476	corneal health	1463:1476	corneal health	1463:1476	These data suggest compositional changes to the diet may be an effective diet-based therapeutic strategy for maintaining or restoring corneal health.					
37085069	7	0	theme	thermal	1118:1124	arg1	stability					1126:1134	thermal stability	1118:1134	thermal stability	1118:1134	In addition, the thermal stability and rheological properties of UC-II/CNs were also improved.					
37085069	4	1	theme	UC-II/CNs	781:789	arg1	forces					771:776	dominant driving forces	754:776	dominant driving forces of UC-II/CNs	754:789	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	8	2	theme	assembly	1210:1217	arg1	process					1219:1225	The composite assembly process	1196:1225	The composite assembly process	1196:1225	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	5	3	theme	surface	980:986	arg1	CNs					997:999	CNs	997:999	CNs	997:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	3	theme	surface	980:986	arg1	group					988:992	surface group	980:992	surface group of CNs	980:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	2	4	dep	66.83-85.06 	585:596	arg1	to					582:583	to	582:583	to	582:583	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	0	5	theme	type	95:98	arg1	collagen					103:110	undenatured type II collagen	83:110	undenatured type II collagen	83:110	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	8	6	theme	functional	1409:1418	arg1	foods					1420:1424	functional foods	1409:1424	functional foods	1409:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	7	theme	UC-II	1266:1270	arg1	process					1219:1225	The composite assembly process	1196:1225	The composite assembly process	1196:1225	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	7	theme	UC-II	1266:1270	arg1	structure					1239:1247	nanofibril structure	1228:1247	nanofibril structure	1228:1247	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	7	theme	UC-II	1266:1270	arg1	levels					1311:1316	levels	1311:1316	levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods	1311:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	7	theme	UC-II	1266:1270	arg1	stability					1253:1261	stability	1253:1261	stability	1253:1261	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	6	8	theme	increased	1075:1083	arg1	charge					1093:1098	the increased surface charge	1071:1098	the increased surface charge	1071:1098	CCNF and TOCNF contributed to the enhanced physical stability due to the increased surface charge.					
37085069	3	9	contain	had	680:682	arg1	CCNF					665:668	CCNF	665:668	CCNF	665:668	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	3	9	contain	had	680:682	arg2	impact					689:694	weak impact	684:694	weak impact	684:694	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	3	9	contain	had	680:682	arg1	TOCNF					674:678	TOCNF	674:678	TOCNF	674:678	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	8	10	from	presence	1279:1286	arg1	process					1219:1225	The composite assembly process	1196:1225	The composite assembly process	1196:1225	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	10	from	presence	1279:1286	arg1	structure					1239:1247	nanofibril structure	1228:1247	nanofibril structure	1228:1247	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	10	from	presence	1279:1286	arg1	levels					1311:1316	levels	1311:1316	levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods	1311:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	10	from	presence	1279:1286	arg1	stability					1253:1261	stability	1253:1261	stability	1253:1261	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	0	11	theme	undenatured	83:93	arg1	collagen					103:110	undenatured type II collagen	83:110	undenatured type II collagen	83:110	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	1	12	theme	undenatured	401:411	arg1	collagen					421:428	undenatured type II collagen	401:428	undenatured type II collagen (UC-II)	401:436	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	12	theme	undenatured	401:411	arg1	UC-II					431:435	UC-II	431:435	UC-II	431:435	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	0	13	theme	collagen	103:110	arg1	stability					70:78	stability	70:78	stability	70:78	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	0	13	theme	collagen	103:110	arg1	structure					56:64	structure	56:64	structure	56:64	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	1	14	theme	TEMPO-oxidized	316:329	arg1	TOCNF					346:350	TOCNF	346:350	TOCNF	346:350	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	14	theme	TEMPO-oxidized	316:329	arg1	nanocellulose					331:343	TEMPO-oxidized nanocellulose	316:343	TEMPO-oxidized nanocellulose (TOCNF)	316:351	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	4	15	theme	dominant	754:761	arg1	forces					771:776	dominant driving forces	754:776	dominant driving forces of UC-II/CNs	754:789	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	1	16	theme	type	413:416	arg1	collagen					421:428	undenatured type II collagen	401:428	undenatured type II collagen (UC-II)	401:436	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	16	theme	type	413:416	arg1	UC-II					431:435	UC-II	431:435	UC-II	431:435	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	6	17	theme	surface	1085:1091	arg1	charge					1093:1098	the increased surface charge	1071:1098	the increased surface charge	1071:1098	CCNF and TOCNF contributed to the enhanced physical stability due to the increased surface charge.					
37085069	3	18	theme	triple	627:632	arg1	structure					640:648	the triple helix structure	623:648	the triple helix structure of UC-II	623:657	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	8	19	from	stability	1253:1261	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	5	20	theme	distinct	912:919	arg1	nanostructures					921:934	distinct nanostructures	912:934	distinct nanostructures due to the differences in shape, level, and surface group of CNs	912:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	8	21	from	levels	1311:1316	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	4	22	theme	UC-II/TOCNF	879:889	arg1	fabrication					849:859	the fabrication	845:859	the fabrication of UC-II/CCNF and UC-II/TOCNF	845:889	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	3	23	theme	helix	634:638	arg1	structure					640:648	the triple helix structure	623:648	the triple helix structure of UC-II	623:657	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	2	24	theme	assembly	551:558	arg1	magnitude					532:540	the magnitude	528:540	the magnitude of UC-II assembly	528:558	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	1	25	theme	collagen	421:428	arg1	process					390:396	the assembly process	377:396	the assembly process of undenatured type II collagen (UC-II)	377:436	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	4	26	theme	electrostatic	796:808	arg1	interactions					810:821	electrostatic interactions	796:821	electrostatic interactions	796:821	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	1	27	theme	cellulose	242:250	arg1	CNF					265:267	CNF	265:267	CNF	265:267	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	27	theme	cellulose	242:250	arg1	nanofibrils					252:262	cellulose nanofibrils	242:262	cellulose nanofibrils (CNF)	242:268	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	2	28	theme	UC-II	545:549	arg1	assembly					551:558	UC-II assembly	545:558	UC-II assembly	545:558	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	8	29	from	structure	1239:1247	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	0	30	theme	composite	17:25	arg1	process					36:42	the composite assembly process	13:42	the composite assembly process	13:42	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	2	31	theme	UC-II	479:483	arg1	assembly					495:502	UC-II composite assembly	479:502	UC-II composite assembly	479:502	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	8	32	theme	types	1301:1305	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	1	33	theme	nanocelluloses	180:193	arg1	types					171:175	Four types	166:175	Four types	166:175	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	33	theme	nanocelluloses	180:193	arg1	nanocellulose					291:303	cationic etherified nanocellulose	271:303	cationic etherified nanocellulose (CCNF)	271:310	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	33	theme	nanocelluloses	180:193	arg1	nanocrystals					222:233	cellulose nanocrystals	212:233	cellulose nanocrystals (CNC)	212:239	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	33	theme	nanocelluloses	180:193	arg1	nanocellulose					331:343	TEMPO-oxidized nanocellulose	316:343	TEMPO-oxidized nanocellulose (TOCNF)	316:351	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	33	theme	nanocelluloses	180:193	arg1	nanofibrils					252:262	cellulose nanofibrils	242:262	cellulose nanofibrils (CNF)	242:268	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	2	34	dep	increased	560:568	arg1	%					597:597	59.93 to 66.83-85.06 %	576:597	59.93 to 66.83-85.06 %	576:597	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	3	35	theme	UC-II	653:657	arg1	structure					640:648	the triple helix structure	623:648	the triple helix structure of UC-II	623:657	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	7	36	dep	stability	1126:1134	arg1	the					1114:1116	the	1114:1116	the	1114:1116	In addition, the thermal stability and rheological properties of UC-II/CNs were also improved.					
37085069	8	37	theme	different	1291:1299	arg1	types					1301:1305	different types	1291:1305	different types	1291:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	5	38	from	differences	947:957	arg1	CNs					997:999	CNs	997:999	CNs	997:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	38	from	differences	947:957	arg1	level					969:973	level	969:973	level	969:973	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	38	from	differences	947:957	arg1	shape					962:966	shape	962:966	shape	962:966	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	38	from	differences	947:957	arg1	group					988:992	surface group	980:992	surface group of CNs	980:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	8	39	theme	composite	1200:1208	arg1	process					1219:1225	The composite assembly process	1196:1225	The composite assembly process	1196:1225	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	0	40	theme	assembly	27:34	arg1	process					36:42	the composite assembly process	13:42	the composite assembly process	13:42	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	3	41	theme	weak	684:687	arg1	impact					689:694	weak impact	684:694	weak impact	684:694	CNC and CNF disrupted the triple helix structure of UC-II while CCNF and TOCNF had weak impact on it.					
37085069	2	42	dep	CNs	458:460	arg1	the					442:444	the	442:444	the	442:444	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	2	42	dep	CNs	458:460	arg1	presence					446:453	presence	446:453	presence	446:453	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	5	43	theme	CNs	997:999	arg1	CNs					997:999	CNs	997:999	CNs	997:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	43	theme	CNs	997:999	arg1	level					969:973	level	969:973	level	969:973	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	43	theme	CNs	997:999	arg1	shape					962:966	shape	962:966	shape	962:966	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	5	43	theme	CNs	997:999	arg1	group					988:992	surface group	980:992	surface group of CNs	980:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	4	44	theme	bonding	712:718	arg1	interactions					736:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	4	45	theme	UC-II/CCNF	864:873	arg1	fabrication					849:859	the fabrication	845:859	the fabrication of UC-II/CCNF and UC-II/TOCNF	845:889	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	0	46	theme	types	141:145	arg1	presence					119:126	the presence	115:126	the presence of different types of nanocelluloses	115:163	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	8	47	theme	CNs	1321:1323	arg1	process					1219:1225	The composite assembly process	1196:1225	The composite assembly process	1196:1225	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	47	theme	CNs	1321:1323	arg1	structure					1239:1247	nanofibril structure	1228:1247	nanofibril structure	1228:1247	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	47	theme	CNs	1321:1323	arg1	levels					1311:1316	levels	1311:1316	levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods	1311:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	47	theme	CNs	1321:1323	arg1	stability					1253:1261	stability	1253:1261	stability	1253:1261	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	2	48	theme	assembly	495:502	arg1	kinetics					467:474	the kinetics	463:474	the kinetics of UC-II composite assembly	463:502	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	6	49	theme	physical	1045:1052	arg1	stability					1054:1062	the enhanced physical stability	1032:1062	the enhanced physical stability due to the increased surface charge	1032:1098	CCNF and TOCNF contributed to the enhanced physical stability due to the increased surface charge.					
37085069	1	50	theme	cationic	271:278	arg1	CCNF					306:309	CCNF	306:309	CCNF	306:309	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	50	theme	cationic	271:278	arg1	nanocellulose					291:303	cationic etherified nanocellulose	271:303	cationic etherified nanocellulose (CCNF)	271:310	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	0	51	theme	different	131:139	arg1	types					141:145	different types	131:145	different types of nanocelluloses	131:163	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	4	52	theme	hydrophobic	724:734	arg1	interactions					736:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	6	53	theme	enhanced	1036:1043	arg1	stability					1054:1062	the enhanced physical stability	1032:1062	the enhanced physical stability due to the increased surface charge	1032:1098	CCNF and TOCNF contributed to the enhanced physical stability due to the increased surface charge.					
37085069	1	54	theme	etherified	280:289	arg1	CCNF					306:309	CCNF	306:309	CCNF	306:309	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	54	theme	etherified	280:289	arg1	nanocellulose					291:303	cationic etherified nanocellulose	271:303	cationic etherified nanocellulose (CCNF)	271:310	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	0	55	theme	nanocelluloses	150:163	arg1	types					141:145	different types	131:145	different types of nanocelluloses	131:163	Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses.					
37085069	8	56	theme	composite	1364:1372	arg1	nanofibrils					1374:1384	the novel composite nanofibrils	1354:1384	the novel composite nanofibrils for the application in functional foods	1354:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	57	from	process	1219:1225	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	2	58	theme	composite	485:493	arg1	assembly					495:502	UC-II composite assembly	479:502	UC-II composite assembly	479:502	In the presence of CNs, the kinetics of UC-II composite assembly slightly fluctuated and the magnitude of UC-II assembly increased (from 59.93 to 66.83-85.06 %).					
37085069	5	59	theme	due	936:938	arg1	nanostructures					921:934	distinct nanostructures	912:934	distinct nanostructures due to the differences in shape, level, and surface group of CNs	912:999	UC-II/CNs exhibited distinct nanostructures due to the differences in shape, level, and surface group of CNs.					
37085069	8	60	from	UC-II	1266:1270	arg1	presence					1279:1286	the presence	1275:1286	the presence of different types	1275:1305	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	8	61	theme	novel	1358:1362	arg1	nanofibrils					1374:1384	the novel composite nanofibrils	1354:1384	the novel composite nanofibrils for the application in functional foods	1354:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	1	62	theme	assembly	381:388	arg1	process					390:396	the assembly process	377:396	the assembly process of undenatured type II collagen (UC-II)	377:436	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	4	63	theme	Hydrogen	703:710	arg1	interactions					736:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions	703:747	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	7	64	theme	UC-II/CNs	1166:1174	arg1	stability					1126:1134	thermal stability	1118:1134	thermal stability	1118:1134	In addition, the thermal stability and rheological properties of UC-II/CNs were also improved.					
37085069	7	64	theme	UC-II/CNs	1166:1174	arg1	properties					1152:1161	rheological properties	1140:1161	rheological properties	1140:1161	In addition, the thermal stability and rheological properties of UC-II/CNs were also improved.					
37085069	1	65	theme	cellulose	212:220	arg1	CNC					236:238	CNC	236:238	CNC	236:238	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	1	65	theme	cellulose	212:220	arg1	nanocrystals					222:233	cellulose nanocrystals	212:233	cellulose nanocrystals (CNC)	212:239	Four types of nanocelluloses (CNs), including cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), cationic etherified nanocellulose (CCNF) and TEMPO-oxidized nanocellulose (TOCNF), were incorporated into the assembly process of undenatured type II collagen (UC-II).					
37085069	7	66	theme	rheological	1140:1150	arg1	properties					1152:1161	rheological properties	1140:1161	rheological properties	1140:1161	In addition, the thermal stability and rheological properties of UC-II/CNs were also improved.					
37085069	8	67	from	application	1394:1404	arg1	foods					1420:1424	functional foods	1409:1424	functional foods	1409:1424	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37085069	4	68	theme	driving	763:769	arg1	forces					771:776	dominant driving forces	754:776	dominant driving forces of UC-II/CNs	754:789	Hydrogen bonding and hydrophobic interactions were dominant driving forces of UC-II/CNs, and electrostatic interactions were also involved in the fabrication of UC-II/CCNF and UC-II/TOCNF.					
37085069	8	69	theme	nanofibril	1228:1237	arg1	structure					1239:1247	nanofibril structure	1228:1247	nanofibril structure	1228:1247	The composite assembly process, nanofibril structure and stability of UC-II in the presence of different types and levels of CNs, which was useful to develop the novel composite nanofibrils for the application in functional foods.					
37387335	3	0	theme	polyaspartic	293:304	arg1	PASP/CMPP					351:359	PASP/CMPP	351:359	PASP/CMPP	351:359	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	0	theme	polyaspartic	293:304	arg1	hydrogels					340:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels	293:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP)	293:360	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	8	1	theme	kinetic	1161:1167	arg1	curves					1169:1174	The sorption kinetic curves	1148:1174	The sorption kinetic curves of Cd(II) on PASP/CMPP	1148:1197	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	7	2	theme	solid	1051:1055	arg1	effect					1071:1076	the solid concentration effect	1047:1076	the solid concentration effect	1047:1076	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	9	3	theme	Freundlich	1333:1342	arg1	models					1364:1369	Freundlich adsorption isotherm models	1333:1369	Freundlich adsorption isotherm models	1333:1369	The adsorption conforms to Langmuir and Freundlich adsorption isotherm models.					
37387335	1	4	theme	metal-contaminated	131:148	arg1	wastewater					150:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	3	5	theme	acid/carboxymethyl	306:323	arg1	PASP/CMPP					351:359	PASP/CMPP	351:359	PASP/CMPP	351:359	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	5	theme	acid/carboxymethyl	306:323	arg1	hydrogels					340:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels	293:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP)	293:360	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	7	6	theme	concentration	1057:1069	arg1	effect					1071:1076	the solid concentration effect	1047:1076	the solid concentration effect	1047:1076	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	5	7	theme	simulated	832:840	arg1	Cd					864:865	simulated wastewater containing Cd	832:865	simulated wastewater containing Cd(II)	832:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	5	7	theme	simulated	832:840	arg1	II					867:868	II	867:868	II	867:868	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	5	8	theme	wastewater	842:851	arg1	Cd					864:865	simulated wastewater containing Cd	832:865	simulated wastewater containing Cd(II)	832:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	5	8	theme	wastewater	842:851	arg1	II					867:868	II	867:868	II	867:868	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	7	9	theme	sorption	1128:1135	arg1	isotherms					1137:1145	sorption isotherms	1128:1145	sorption isotherms	1128:1145	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	10	10	theme	PASP/CMPP	1390:1398	arg1	composites					1400:1409	PASP/CMPP composites	1390:1409	PASP/CMPP composites	1390:1409	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	10	10	theme	PASP/CMPP	1390:1398	arg1	kind					1444:1447	a new kind	1438:1447	a new kind of environmental adsorbent for wastewater treatment	1438:1499	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	7	11	located	found	1082:1086	arg1	process					1095:1101	the process	1091:1101	the process of sorption kinetics and sorption isotherms	1091:1145	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	7	11	located	found	1082:1086	arg2	effect					1071:1076	the solid concentration effect	1047:1076	the solid concentration effect	1047:1076	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	2	12	theme	metal	265:269	arg1	contaminants					271:282	heavy metal contaminants	259:282	heavy metal contaminants	259:282	Adsorbents are a promising method for the removal of heavy metal contaminants.					
37387335	6	13	theme	adsorption	963:972	arg1	effect					974:979	a better adsorption effect	954:979	a better adsorption effect	954:979	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	0	14	theme	Cd	83:84	arg1	efficiency					69:78	their removal efficiency	55:78	their removal efficiency of Cd(II) from aqueous solutions	55:111	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	0	14	theme	Cd	83:84	arg1	cellulose					41:49	poplar cellulose	34:49	poplar cellulose	34:49	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	2	15	theme	heavy	259:263	arg1	contaminants					271:282	heavy metal contaminants	259:282	heavy metal contaminants	259:282	Adsorbents are a promising method for the removal of heavy metal contaminants.					
37387335	8	16	theme	adsorbent	1267:1275	arg1	concentrations					1277:1290	different adsorbent concentrations	1257:1290	different adsorbent concentrations	1257:1290	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	3	17	theme	vitamin	537:543	arg1	C					545:545	vitamin C	537:545	vitamin C	537:545	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	7	18	theme	kinetics	1115:1122	arg1	process					1095:1101	the process	1091:1101	the process of sorption kinetics and sorption isotherms	1091:1145	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	3	19	theme	alkalized	475:483	arg1	CMPP					501:504	CMPP	501:504	CMPP	501:504	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	19	theme	alkalized	475:483	arg1	sawdust					492:498	alkalized poplar sawdust	475:498	alkalized poplar sawdust (CMPP)	475:505	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	19	theme	alkalized	475:483	arg1	modifiers					555:563	modifiers	555:563	modifiers	555:563	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	19	theme	alkalized	475:483	arg1	substrate					514:522	the substrate	510:522	the substrate	510:522	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	4	20	theme	pores	728:732	arg1	volume					752:757	a larger pore volume	738:757	a larger pore volume	738:757	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	20	theme	pores	728:732	arg1	number					712:717	a larger number	703:717	a larger number of loose pores	703:732	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	21	theme	SEM	634:636	arg1	analysis					622:629	the characterization analysis	601:629	the characterization analysis of SEM	601:636	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	21	theme	SEM	634:636	arg1	BET					642:644	BET	642:644	BET	642:644	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	8	22	theme	sorption	1152:1159	arg1	curves					1169:1174	The sorption kinetic curves	1148:1174	The sorption kinetic curves of Cd(II) on PASP/CMPP	1148:1197	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	4	23	theme	loose	722:726	arg1	pores					728:732	loose pores	722:732	loose pores	722:732	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	6	24	theme	adsorption	1009:1018	arg1	conditions					1020:1029	the same adsorption conditions	1000:1029	the same adsorption conditions	1000:1029	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	3	25	theme	acid/carboxymethyl	375:392	arg1	hydrogels					409:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels	366:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP)	366:427	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	25	theme	acid/carboxymethyl	375:392	arg1	VC/CMPP					420:426	VC/CMPP	420:426	VC/CMPP	420:426	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	10	26	used	used	1430:1433	arg2	kind					1444:1447	a new kind	1438:1447	a new kind of environmental adsorbent for wastewater treatment	1438:1499	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	10	26	used	used	1430:1433	arg2	composites					1400:1409	PASP/CMPP composites	1390:1409	PASP/CMPP composites	1390:1409	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	3	27	theme	poplar	325:330	arg1	PASP/CMPP					351:359	PASP/CMPP	351:359	PASP/CMPP	351:359	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	27	theme	poplar	325:330	arg1	hydrogels					340:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels	293:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP)	293:360	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	28	theme	ascorbic	366:373	arg1	hydrogels					409:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels	366:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP)	366:427	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	28	theme	ascorbic	366:373	arg1	VC/CMPP					420:426	VC/CMPP	420:426	VC/CMPP	420:426	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	29	theme	poplar	394:399	arg1	hydrogels					409:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels	366:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP)	366:427	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	29	theme	poplar	394:399	arg1	VC/CMPP					420:426	VC/CMPP	420:426	VC/CMPP	420:426	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	4	30	theme	hydrogel	690:697	arg1	surface					665:671	the surface	661:671	the surface of the PASP/CMPP hydrogel	661:697	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	8	31	theme	Cd	1179:1180	arg1	curves					1169:1174	The sorption kinetic curves	1148:1174	The sorption kinetic curves of Cd(II) on PASP/CMPP	1148:1197	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	0	32	theme	aqueous	95:101	arg1	solutions					103:111	aqueous solutions	95:111	aqueous solutions	95:111	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	4	33	theme	larger	705:710	arg1	number					712:717	a larger number	703:717	a larger number of loose pores	703:732	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	1	34	theme	main	175:178	arg1	problems					196:203	the main water pollution problems	171:203	the main water pollution problems	171:203	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	0	35	theme	hydrogels	15:23	arg1	Preparation					0:10	Preparation	0:10	Preparation of hydrogels	0:23	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	6	36	contain	had	950:952	arg1	PASP/CMPP					940:948	PASP/CMPP	940:948	PASP/CMPP	940:948	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	6	36	contain	had	950:952	arg2	effect					974:979	a better adsorption effect	954:979	a better adsorption effect	954:979	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	2	37	theme	contaminants	271:282	arg1	removal					248:254	the removal	244:254	the removal of heavy metal contaminants	244:282	Adsorbents are a promising method for the removal of heavy metal contaminants.					
37387335	1	38	theme	water	180:184	arg1	problems					196:203	the main water pollution problems	171:203	the main water pollution problems	171:203	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	0	39	theme	poplar	34:39	arg1	cellulose					41:49	poplar cellulose	34:49	poplar cellulose	34:49	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	4	40	contain	has	699:701	arg2	volume					752:757	a larger pore volume	738:757	a larger pore volume	738:757	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	40	contain	has	699:701	arg1	surface					665:671	the surface	661:671	the surface of the PASP/CMPP hydrogel	661:697	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	40	contain	has	699:701	arg2	number					712:717	a larger number	703:717	a larger number of loose pores	703:732	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	3	41	theme	aqueous	446:452	arg1	polymerization					454:467	aqueous polymerization	446:467	aqueous polymerization	446:467	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	9	42	theme	isotherm	1355:1362	arg1	models					1364:1369	Freundlich adsorption isotherm models	1333:1369	Freundlich adsorption isotherm models	1333:1369	The adsorption conforms to Langmuir and Freundlich adsorption isotherm models.					
37387335	1	43	theme	pollution	186:194	arg1	problems					196:203	the main water pollution problems	171:203	the main water pollution problems	171:203	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	6	44	theme	same	1004:1007	arg1	conditions					1020:1029	the same adsorption conditions	1000:1029	the same adsorption conditions	1000:1029	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	10	45	theme	wastewater	1480:1489	arg1	treatment					1491:1499	wastewater treatment	1480:1499	wastewater treatment	1480:1499	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	5	46	theme	treatment	790:798	arg1	effects					800:806	The treatment effects	786:806	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II)	786:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	1	47	theme	problems	196:203	arg1	one					164:166	one	164:166	one	164:166	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	1	47	theme	problems	196:203	arg1	problems					196:203	the main water pollution problems	171:203	the main water pollution problems	171:203	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	3	48	theme	sawdust	401:407	arg1	hydrogels					409:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels	366:417	ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP)	366:427	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	48	theme	sawdust	401:407	arg1	VC/CMPP					420:426	VC/CMPP	420:426	VC/CMPP	420:426	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	5	49	theme	hydrogels	819:827	arg1	effects					800:806	The treatment effects	786:806	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II)	786:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	6	50	theme	better	956:961	arg1	effect					974:979	a better adsorption effect	954:979	a better adsorption effect	954:979	The results showed that PASP/CMPP had a better adsorption effect than VC/CMPP under the same adsorption conditions.					
37387335	4	51	theme	VC/CMPP	768:774	arg1	hydrogel					776:783	the VC/CMPP hydrogel	764:783	the VC/CMPP hydrogel	764:783	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	5	52	theme	containing	853:862	arg1	Cd					864:865	simulated wastewater containing Cd	832:865	simulated wastewater containing Cd(II)	832:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	5	52	theme	containing	853:862	arg1	II					867:868	II	867:868	II	867:868	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	4	53	theme	effective	570:578	arg1	results					580:586	The effective results	566:586	The effective results	566:586	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	10	54	theme	adsorbent	1466:1474	arg1	composites					1400:1409	PASP/CMPP composites	1390:1409	PASP/CMPP composites	1390:1409	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	10	54	theme	adsorbent	1466:1474	arg1	kind					1444:1447	a new kind	1438:1447	a new kind of environmental adsorbent for wastewater treatment	1438:1499	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	4	55	theme	PASP/CMPP	680:688	arg1	hydrogel					690:697	the PASP/CMPP hydrogel	676:697	the PASP/CMPP hydrogel	676:697	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	56	theme	larger	740:745	arg1	volume					752:757	a larger pore volume	738:757	a larger pore volume	738:757	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	8	57	from	curves	1169:1174	arg1	PASP/CMPP					1189:1197	PASP/CMPP	1189:1197	PASP/CMPP	1189:1197	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	3	58	theme	poplar	485:490	arg1	CMPP					501:504	CMPP	501:504	CMPP	501:504	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	58	theme	poplar	485:490	arg1	sawdust					492:498	alkalized poplar sawdust	475:498	alkalized poplar sawdust (CMPP)	475:505	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	58	theme	poplar	485:490	arg1	modifiers					555:563	modifiers	555:563	modifiers	555:563	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	58	theme	poplar	485:490	arg1	substrate					514:522	the substrate	510:522	the substrate	510:522	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	10	59	theme	new	1440:1442	arg1	composites					1400:1409	PASP/CMPP composites	1390:1409	PASP/CMPP composites	1390:1409	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	10	59	theme	new	1440:1442	arg1	kind					1444:1447	a new kind	1438:1447	a new kind of environmental adsorbent for wastewater treatment	1438:1499	More importantly, PASP/CMPP composites are expected to be used as a new kind of environmental adsorbent for wastewater treatment.					
37387335	5	60	theme	experiments	903:913	arg1	batch					894:898	a batch	892:898	a batch of experiments	892:913	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	8	61	theme	quasi-second-order	1223:1240	arg1	kinetics					1242:1249	the quasi-second-order kinetics	1219:1249	the quasi-second-order kinetics	1219:1249	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	8	62	theme	different	1257:1265	arg1	concentrations					1277:1290	different adsorbent concentrations	1257:1290	different adsorbent concentrations	1257:1290	The sorption kinetic curves of Cd(II) on PASP/CMPP were well-fitted by the quasi-second-order kinetics under different adsorbent concentrations.					
37387335	0	63	from	solutions	103:111	arg1	efficiency					69:78	their removal efficiency	55:78	their removal efficiency of Cd(II) from aqueous solutions	55:111	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	0	63	from	solutions	103:111	arg1	cellulose					41:49	poplar cellulose	34:49	poplar cellulose	34:49	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	0	64	theme	removal	61:67	arg1	efficiency					69:78	their removal efficiency	55:78	their removal efficiency of Cd(II) from aqueous solutions	55:111	Preparation of hydrogels based on poplar cellulose and their removal efficiency of Cd(II) from aqueous solutions.					
37387335	4	65	theme	characterization	605:620	arg1	analysis					622:629	the characterization analysis	601:629	the characterization analysis of SEM	601:636	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	4	66	theme	pore	747:750	arg1	volume					752:757	a larger pore volume	738:757	a larger pore volume	738:757	The effective results, provided by the characterization analysis of SEM and BET, indicate that the surface of the PASP/CMPP hydrogel has a larger number of loose pores and a larger pore volume than the VC/CMPP hydrogel.					
37387335	1	67	theme	Industrial	114:123	arg1	wastewater					150:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	9	68	theme	adsorption	1344:1353	arg1	models					1364:1369	Freundlich adsorption isotherm models	1333:1369	Freundlich adsorption isotherm models	1333:1369	The adsorption conforms to Langmuir and Freundlich adsorption isotherm models.					
37387335	3	69	theme	sawdust	332:338	arg1	PASP/CMPP					351:359	PASP/CMPP	351:359	PASP/CMPP	351:359	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	3	69	theme	sawdust	332:338	arg1	hydrogels					340:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels	293:348	polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP)	293:360	Herein, polyaspartic acid/carboxymethyl poplar sawdust hydrogels (PASP/CMPP) and ascorbic acid/carboxymethyl poplar sawdust hydrogels (VC/CMPP) were prepared by aqueous polymerization using alkalized poplar sawdust (CMPP) as the substrate and PASP and vitamin C (VC) as modifiers.					
37387335	2	70	theme	promising	223:231	arg1	method					233:238	a promising method	221:238	a promising method for the removal of heavy metal contaminants	221:282	Adsorbents are a promising method for the removal of heavy metal contaminants.					
37387335	2	70	theme	promising	223:231	arg1	Adsorbents					206:215	Adsorbents	206:215	Adsorbents	206:215	Adsorbents are a promising method for the removal of heavy metal contaminants.					
37387335	5	71	from	effects	800:806	arg1	Cd					864:865	simulated wastewater containing Cd	832:865	simulated wastewater containing Cd(II)	832:869	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	5	71	from	effects	800:806	arg1	II					867:868	II	867:868	II	867:868	The treatment effects of the two hydrogels on simulated wastewater containing Cd(II) were investigated by a batch of experiments.					
37387335	1	72	theme	heavy	125:129	arg1	wastewater					150:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater	114:159	Industrial heavy metal-contaminated wastewater is one of the main water pollution problems.					
37387335	7	73	theme	sorption	1106:1113	arg1	kinetics					1115:1122	sorption kinetics	1106:1122	sorption kinetics	1106:1122	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
37387335	7	74	theme	isotherms	1137:1145	arg1	process					1095:1101	the process	1091:1101	the process of sorption kinetics and sorption isotherms	1091:1145	Interestingly, the solid concentration effect was found in the process of sorption kinetics and sorption isotherms.					
36243153	4	0	theme	structural	579:588	arg1	stability					590:598	structural stability	579:598	structural stability	579:598	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	6	1	theme	high	1056:1059	arg1	hydrophobicity					1069:1082	high surface hydrophobicity	1056:1082	high surface hydrophobicity	1056:1082	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	4	2	theme	AMFC	669:672	arg1	addition					657:664	the addition	653:664	the addition of AMFC due to the formation of a hybrid network structure	653:723	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	5	3	dep	1.52 MPa	782:789	arg1	up					776:777	up	776:777	up	776:777	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	6	4	theme	gelatin-based	967:979	arg1	hydrogels					991:999	the developed gelatin-based composite hydrogels	953:999	the developed gelatin-based composite hydrogels reinforced with AMFC	953:1020	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	5	5	link	genipin-crosslinked	890:908	arg1	hydrogels					918:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	6	6	theme	potential	1170:1178	arg1	applications					1180:1191	potential applications	1170:1191	potential applications	1170:1191	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	7	contain	have	1165:1168	arg1	hydrophobicity					1069:1082	high surface hydrophobicity	1056:1082	high surface hydrophobicity	1056:1082	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	7	contain	have	1165:1168	arg1	stability					1045:1053	good enzymatic stability	1030:1053	good enzymatic stability	1030:1053	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	7	contain	have	1165:1168	arg1	property					1102:1109	tunable swelling property	1085:1109	tunable swelling property	1085:1109	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	7	contain	have	1165:1168	arg1	biocompatibility					1125:1140	excellent biocompatibility	1115:1140	excellent biocompatibility	1115:1140	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	7	contain	have	1165:1168	arg2	applications					1180:1191	potential applications	1170:1191	potential applications	1170:1191	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	2	8	theme	physical	361:368	arg1	crosslinks					370:379	chemical and physical crosslinks	348:379	chemical and physical crosslinks among gelatin chains and AMFC fibrils	348:417	The hydrogel consists of chemical and physical crosslinks among gelatin chains and AMFC fibrils.					
36243153	6	9	theme	surface	1061:1067	arg1	hydrophobicity					1069:1082	high surface hydrophobicity	1056:1082	high surface hydrophobicity	1056:1082	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	10	theme	developed	957:965	arg1	hydrogels					991:999	the developed gelatin-based composite hydrogels	953:999	the developed gelatin-based composite hydrogels reinforced with AMFC	953:1020	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	4	11	theme	mechanical	553:562	arg1	properties					564:573	the mechanical properties	549:573	the mechanical properties	549:573	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	2	12	theme	chemical	348:355	arg1	crosslinks					370:379	chemical and physical crosslinks	348:379	chemical and physical crosslinks among gelatin chains and AMFC fibrils	348:417	The hydrogel consists of chemical and physical crosslinks among gelatin chains and AMFC fibrils.					
36243153	5	13	theme	gelatin	910:916	arg1	hydrogels					918:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	5	14	theme	physical	877:884	arg1	hydrogels					918:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	0	15	link	Genipin-crosslinked	0:18	arg1	hydrogels					44:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	3	16	theme	hydrogels	498:506	arg1	morphology					424:433	The morphology	420:433	The morphology	420:433	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	3	16	theme	hydrogels	498:506	arg1	behavior					445:452	swelling behavior	436:452	swelling behavior	436:452	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	3	16	theme	hydrogels	498:506	arg1	properties					470:479	compressive properties	458:479	compressive properties	458:479	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	1	17	theme	amino-functionalized	215:234	arg1	cellulose					253:261	amino-functionalized microfibrillated cellulose	215:261	amino-functionalized microfibrillated cellulose (AMFC)	215:268	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	1	17	theme	amino-functionalized	215:234	arg1	AMFC					264:267	AMFC	264:267	AMFC	264:267	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	5	18	theme	%	809:809	arg1	strain					796:801	a strain	794:801	a strain	794:801	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	5	18	theme	%	809:809	arg1	41.2					821:824	41.2	821:824	41.2	821:824	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	3	19	theme	compressive	458:468	arg1	properties					470:479	compressive properties	458:479	compressive properties	458:479	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	1	20	theme	microfibrillated	236:251	arg1	cellulose					253:261	amino-functionalized microfibrillated cellulose	215:261	amino-functionalized microfibrillated cellulose (AMFC)	215:268	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	1	20	theme	microfibrillated	236:251	arg1	AMFC					264:267	AMFC	264:267	AMFC	264:267	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	0	21	theme	gelatin-based	20:32	arg1	hydrogels					44:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	6	22	theme	good	1030:1033	arg1	stability					1045:1053	good enzymatic stability	1030:1053	good enzymatic stability	1030:1053	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	2	23	theme	gelatin	387:393	arg1	chains					395:400	gelatin chains	387:400	gelatin chains	387:400	The hydrogel consists of chemical and physical crosslinks among gelatin chains and AMFC fibrils.					
36243153	1	24	theme	cellulose	253:261	arg1	incorporation					198:210	incorporation	198:210	incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix	198:288	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	0	25	theme	Genipin-crosslinked	0:18	arg1	hydrogels					44:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	1	26	theme	strong	129:134	arg1	hydrogel					171:178	a strong and stable gelatin-based composite hydrogel	127:178	a strong and stable gelatin-based composite hydrogel	127:178	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	5	27	theme	composite	730:738	arg1	hydrogel					740:747	The composite hydrogel	726:747	The composite hydrogel	726:747	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	3	28	theme	swelling	436:443	arg1	behavior					445:452	swelling behavior	436:452	swelling behavior	436:452	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	4	29	theme	network	707:713	arg1	structure					715:723	a hybrid network structure	698:723	a hybrid network structure	698:723	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	0	30	theme	composite	34:42	arg1	hydrogels					44:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels	0:52	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	6	31	theme	enzymatic	1035:1043	arg1	stability					1045:1053	good enzymatic stability	1030:1053	good enzymatic stability	1030:1053	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	5	32	dep	41.2	821:824	arg1	higher					840:845	higher	840:845	higher	840:845	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	1	33	theme	stable	140:145	arg1	hydrogel					171:178	a strong and stable gelatin-based composite hydrogel	127:178	a strong and stable gelatin-based composite hydrogel	127:178	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	6	34	theme	composite	981:989	arg1	hydrogels					991:999	the developed gelatin-based composite hydrogels	953:999	the developed gelatin-based composite hydrogels reinforced with AMFC	953:1020	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	4	35	theme	hybrid	700:705	arg1	structure					715:723	a hybrid network structure	698:723	a hybrid network structure	698:723	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	2	36	theme	AMFC	406:409	arg1	fibrils					411:417	AMFC fibrils	406:417	AMFC fibrils	406:417	The hydrogel consists of chemical and physical crosslinks among gelatin chains and AMFC fibrils.					
36243153	3	37	theme	composite	488:496	arg1	hydrogels					498:506	the composite hydrogels	484:506	the composite hydrogels	484:506	The morphology, swelling behavior and compressive properties of the composite hydrogels were investigated.					
36243153	4	38	theme	hydrogels	615:623	arg1	properties					564:573	the mechanical properties	549:573	the mechanical properties	549:573	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	4	38	theme	hydrogels	615:623	arg1	stability					590:598	structural stability	579:598	structural stability	579:598	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	5	39	from	strain	796:801	arg1	1.52 MPa					782:789	1.52 MPa	782:789	1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively	782:940	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	5	40	theme	genipin-crosslinked	890:908	arg1	hydrogels					918:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	1	41	theme	gelatin	275:281	arg1	matrix					283:288	gelatin matrix	275:288	gelatin matrix	275:288	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	0	42	theme	microfibrillated	91:106	arg1	cellulose					108:116	amino-functionalized microfibrillated cellulose	70:116	amino-functionalized microfibrillated cellulose	70:116	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	4	43	theme	gelatin	607:613	arg1	hydrogels					615:623	the gelatin hydrogels	603:623	the gelatin hydrogels	603:623	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	6	44	theme	excellent	1115:1123	arg1	biocompatibility					1125:1140	excellent biocompatibility	1115:1140	excellent biocompatibility	1115:1140	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	1	45	theme	gelatin-based	147:159	arg1	hydrogel					171:178	a strong and stable gelatin-based composite hydrogel	127:178	a strong and stable gelatin-based composite hydrogel	127:178	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	0	46	theme	amino-functionalized	70:89	arg1	cellulose					108:116	amino-functionalized microfibrillated cellulose	70:116	amino-functionalized microfibrillated cellulose	70:116	Genipin-crosslinked gelatin-based composite hydrogels reinforced with amino-functionalized microfibrillated cellulose.					
36243153	5	47	theme	compressive	755:765	arg1	strength					767:774	a compressive strength	753:774	a compressive strength	753:774	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	1	48	theme	composite	161:169	arg1	hydrogel					171:178	a strong and stable gelatin-based composite hydrogel	127:178	a strong and stable gelatin-based composite hydrogel	127:178	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36243153	6	49	theme	pharmaceutical	1211:1224	arg1	fields					1226:1231	biomedical and pharmaceutical fields	1196:1231	biomedical and pharmaceutical fields	1196:1231	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	5	50	contain	has	749:751	arg1	hydrogel					740:747	The composite hydrogel	726:747	The composite hydrogel	726:747	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	5	50	contain	has	749:751	arg2	strength					767:774	a compressive strength	753:774	a compressive strength	753:774	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	4	51	theme	structure	715:723	arg1	formation					685:693	the formation	681:693	the formation of a hybrid network structure	681:723	The results show that the mechanical properties and structural stability of the gelatin hydrogels were improved remarkably by the addition of AMFC due to the formation of a hybrid network structure.					
36243153	5	52	theme	conventional	864:875	arg1	hydrogels					918:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	the conventional physical and genipin-crosslinked gelatin hydrogels	860:926	The composite hydrogel has a compressive strength up to 1.52 MPa at a strain of 80 %, which is 41.2 and 1.8 times higher than that of the conventional physical and genipin-crosslinked gelatin hydrogels, respectively.					
36243153	6	53	theme	biomedical	1196:1205	arg1	fields					1226:1231	biomedical and pharmaceutical fields	1196:1231	biomedical and pharmaceutical fields	1196:1231	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	54	theme	swelling	1093:1100	arg1	property					1102:1109	tunable swelling property	1085:1109	tunable swelling property	1085:1109	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	6	55	theme	tunable	1085:1091	arg1	property					1102:1109	tunable swelling property	1085:1109	tunable swelling property	1085:1109	Moreover, the developed gelatin-based composite hydrogels reinforced with AMFC exhibit good enzymatic stability, high surface hydrophobicity, tunable swelling property and excellent biocompatibility, which are expected to have potential applications in biomedical and pharmaceutical fields.					
36243153	1	56	theme	genipin	301:307	arg1	crosslinking					309:320	genipin crosslinking	301:320	genipin crosslinking	301:320	Herein, a strong and stable gelatin-based composite hydrogel was fabricated by incorporation of amino-functionalized microfibrillated cellulose (AMFC) into gelatin matrix along with genipin crosslinking.					
36549607	3	0	theme	high	550:553	arg1	properties					566:575	high mechanical properties	550:575	high mechanical properties	550:575	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	3	1	theme	mechanical	555:564	arg1	properties					566:575	high mechanical properties	550:575	high mechanical properties	550:575	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	3	2	theme	new	416:418	arg1	PDMS-PU					443:449	PDMS-PU	443:449	PDMS-PU	443:449	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	3	2	theme	new	416:418	arg1	polysiloxane-polyurea					420:440	new polysiloxane-polyurea	416:440	new polysiloxane-polyurea (PDMS-PU)	416:450	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	2	3	theme	materials	348:356	arg1	efficiency					334:343	self-healing efficiency	321:343	self-healing efficiency	321:343	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	2	3	theme	materials	348:356	arg1	strength					308:315	mechanical strength	297:315	mechanical strength	297:315	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	4	4	theme	CNF/PDMS-PU	640:650	arg1	materials					662:670	CNF/PDMS-PU composite materials	640:670	CNF/PDMS-PU composite materials	640:670	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	5	5	theme	healing	946:952	arg1	efficiency					954:963	healing efficiency	946:963	healing efficiency of 95.58 %	946:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	6	6	theme	PDMS	1149:1152	arg1	materials					1154:1162	PDMS materials	1149:1162	PDMS materials	1149:1162	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	4	7	theme	great	687:691	arg1	resistance					701:710	the great bending resistance	683:710	the great bending resistance	683:710	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	2	8	theme	self-healing	321:332	arg1	efficiency					334:343	self-healing efficiency	321:343	self-healing efficiency	321:343	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	5	9	theme	%	974:974	arg1	efficiency					954:963	healing efficiency	946:963	healing efficiency of 95.58 %	946:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	10	theme	%	917:917	arg1	content					904:910	CNF content	900:910	CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %	900:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	11	theme	PDMS-PU	847:853	arg1	efficiency					833:842	the self-healing efficiency	816:842	the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %	816:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	4	12	theme	composite	652:660	arg1	materials					662:670	CNF/PDMS-PU composite materials	640:670	CNF/PDMS-PU composite materials	640:670	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	6	13	theme	composite	1105:1113	arg1	materials					1115:1123	PDMS-PU composite materials	1097:1123	PDMS-PU composite materials	1097:1123	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	6	14	theme	PDMS-PU	1097:1103	arg1	materials					1115:1123	PDMS-PU composite materials	1097:1123	PDMS-PU composite materials	1097:1123	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	5	15	theme	disulfide	879:887	arg1	bonds					889:893	disulfide bonds	879:893	disulfide bonds	879:893	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	4	16	theme	reprocessing	730:741	arg1	properties					743:752	reprocessing properties	730:752	reprocessing properties of PDMS-PU	730:763	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	0	17	theme	nanofiber/polysiloxane-polyurea	23:53	arg1	materials					65:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	5	18	theme	tensile	985:991	arg1	strength					993:1000	the tensile strength	981:1000	the tensile strength after three recycling processing	981:1033	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	18	theme	tensile	985:991	arg1	high					1048:1051	high	1048:1051	high	1048:1051	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	4	19	theme	bending	693:699	arg1	resistance					701:710	the great bending resistance	683:710	the great bending resistance	683:710	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	0	20	theme	cellulose	13:21	arg1	materials					65:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	5	21	theme	recycling	1014:1022	arg1	processing					1024:1033	three recycling processing	1008:1033	three recycling processing	1008:1033	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	1	22	theme	self-recoverability	138:156	arg1	ability					158:164	the self-recoverability ability	134:164	the self-recoverability ability of organisms	134:177	Inspired by the self-recoverability ability of organisms, various self-healing materials have been developed.					
36549607	4	23	theme	PDMS-PU	757:763	arg1	resistance					701:710	the great bending resistance	683:710	the great bending resistance	683:710	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	4	23	theme	PDMS-PU	757:763	arg1	transparency					713:724	transparency	713:724	transparency	713:724	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	4	23	theme	PDMS-PU	757:763	arg1	properties					743:752	reprocessing properties	730:752	reprocessing properties of PDMS-PU	730:763	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	0	24	theme	materials	65:73	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.	0:120	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	4	25	theme	PDMS-PU	617:623	arg1	strength					605:612	the tensile strength	593:612	the tensile strength of PDMS-PU	593:623	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	0	26	theme	composite	55:63	arg1	materials					65:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	cellulose nanofiber/polysiloxane-polyurea composite materials	13:73	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	3	27	theme	matrix	467:472	arg1	resin					474:478	matrix resin	467:478	matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties	467:575	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	0	28	theme	self-healing	80:91	arg1	properties					110:119	self-healing and reprocessing properties	80:119	self-healing and reprocessing properties	80:119	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	5	29	theme	CNFs	796:799	arg1	introduction					780:791	the introduction	776:791	the introduction of CNFs	776:799	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	30	contain	containing	868:877	arg1	PDMS-PU					847:853	PDMS-PU	847:853	PDMS-PU	847:853	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	30	contain	containing	868:877	arg2	bonds					889:893	disulfide bonds	879:893	disulfide bonds	879:893	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	6	31	theme	advanced	1167:1174	arg1	fields					1188:1193	advanced engineering fields	1167:1193	advanced engineering fields that require high strength durability and good formability	1167:1252	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	5	32	theme	PDMS-PU	860:866	arg1	efficiency					833:842	the self-healing efficiency	816:842	the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %	816:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	4	33	theme	tensile	597:603	arg1	strength					605:612	the tensile strength	593:612	the tensile strength of PDMS-PU	593:623	CNFs increased the tensile strength of PDMS-PU by 38.87 % and CNF/PDMS-PU composite materials maintained the great bending resistance, transparency and reprocessing properties of PDMS-PU.					
36549607	3	34	used	used	456:459	arg2	we					398:399	we	398:399	we	398:399	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	5	35	theme	original	1071:1078	arg1	%					1062:1062	92.55 %	1056:1062	92.55 % of the original	1056:1078	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	35	theme	original	1071:1078	arg1	original					1071:1078	original	1071:1078	original	1071:1078	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	5	36	with	%	917:917	arg1	efficiency					954:963	healing efficiency	946:963	healing efficiency of 95.58 %	946:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	2	37	theme	reinforced	246:255	arg1	fillers					257:263	most reinforced fillers	241:263	most reinforced fillers	241:263	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	0	38	with	Synthesis	0:8	arg1	properties					110:119	self-healing and reprocessing properties	80:119	self-healing and reprocessing properties	80:119	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	1	39	theme	organisms	169:177	arg1	ability					158:164	the self-recoverability ability	134:164	the self-recoverability ability of organisms	134:177	Inspired by the self-recoverability ability of organisms, various self-healing materials have been developed.					
36549607	6	40	theme	high	1208:1211	arg1	durability					1222:1231	high strength durability	1208:1231	high strength durability	1208:1231	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	2	41	theme	most	241:244	arg1	fillers					257:263	most reinforced fillers	241:263	most reinforced fillers	241:263	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	2	42	theme	mechanical	297:306	arg1	strength					308:315	mechanical strength	297:315	mechanical strength	297:315	However, most reinforced fillers are faced with the problem that mechanical strength and self-healing efficiency of materials cannot be improved simultaneously.					
36549607	3	43	theme	composite	525:533	arg1	materials					535:543	cellulose nanofiber (CNF)/PDMS-PU composite materials	491:543	cellulose nanofiber (CNF)/PDMS-PU composite materials	491:543	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	3	44	theme	/PDMS-PU	516:523	arg1	materials					535:543	cellulose nanofiber (CNF)/PDMS-PU composite materials	491:543	cellulose nanofiber (CNF)/PDMS-PU composite materials	491:543	Here we first prepared new polysiloxane-polyurea (PDMS-PU) and used it as matrix resin to prepare cellulose nanofiber (CNF)/PDMS-PU composite materials with high mechanical properties.					
36549607	0	45	theme	reprocessing	97:108	arg1	properties					110:119	self-healing and reprocessing properties	80:119	self-healing and reprocessing properties	80:119	Synthesis of cellulose nanofiber/polysiloxane-polyurea composite materials with self-healing and reprocessing properties.					
36549607	5	46	theme	CNF	900:902	arg1	content					904:910	CNF content	900:910	CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %	900:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	1	47	theme	various	180:186	arg1	materials					201:209	various self-healing materials	180:209	various self-healing materials	180:209	Inspired by the self-recoverability ability of organisms, various self-healing materials have been developed.					
36549607	6	48	theme	strength	1213:1220	arg1	durability					1222:1231	high strength durability	1208:1231	high strength durability	1208:1231	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	5	49	theme	self-healing	820:831	arg1	efficiency					833:842	the self-healing efficiency	816:842	the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %	816:974	Moreover, the introduction of CNFs did not reduce the self-healing efficiency of PDMS-PU, and PDMS-PU containing disulfide bonds with CNF content of 1 % (CNF/PDMS-IPDI-S-1 %) with healing efficiency of 95.58 %, and the tensile strength after three recycling processing was still as high as 92.55 % of the original.					
36549607	6	50	theme	engineering	1176:1186	arg1	fields					1188:1193	advanced engineering fields	1167:1193	advanced engineering fields that require high strength durability and good formability	1167:1252	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	6	51	theme	good	1237:1240	arg1	formability					1242:1252	good formability	1237:1252	good formability	1237:1252	CNFs reinforced PDMS-PU composite materials are expected to replace PDMS materials in advanced engineering fields that require high strength durability and good formability.					
36549607	1	52	theme	self-healing	188:199	arg1	materials					201:209	various self-healing materials	180:209	various self-healing materials	180:209	Inspired by the self-recoverability ability of organisms, various self-healing materials have been developed.					
35861162	14	0	theme	EVIDENCE	2392:2399	arg1	EFFICACY					2419:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY: Stage 2.					
35861162	9	1	theme	Rho	1628:1630	arg1	test					1632:1635	Spearman's Rho test	1617:1635	Spearman's Rho test	1617:1635	STATISTICAL TESTS Normality was tested using Shapiro-Wilk test, and association between predicted and measured values was evaluated using Spearman's Rho test.					
35861162	4	2	theme	Shetland	646:653	arg1	ponies					655:660	10 Shetland ponies	643:660	10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	643:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	8	3	theme	collagen	1327:1334	arg1	orientation					1342:1352	collagen fiber orientation	1327:1352	collagen fiber orientation	1327:1352	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	11	4	theme	cartilage	1926:1934	arg1	properties					1943:1952	predicted cartilage matrix properties	1916:1952	predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD)	1916:2010	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	1	5	theme	structural	296:305	arg1	composition					307:317	the structural composition	292:317	the structural composition of articular cartilage	292:340	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	6	6	theme	random	1079:1084	arg1	RF					1094:1095	RF	1094:1095	RF	1094:1095	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	6	theme	random	1079:1084	arg1	forest					1086:1091	random forest	1079:1091	random forest (RF)	1079:1096	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	10	7	theme	significance	1699:1710	arg1	limit					1678:1682	the limit	1674:1682	the limit of statistical significance	1674:1710	A P-value of 0.05 was considered as the limit of statistical significance.					
35861162	10	7	theme	significance	1699:1710	arg1	P-value					1640:1646	A P-value	1638:1646	A P-value of 0.05	1638:1654	A P-value of 0.05 was considered as the limit of statistical significance.					
35861162	1	8	theme	quantitative	209:220	arg1	MRIs					222:225	multiparametric quantitative MRIs	193:225	multiparametric quantitative MRIs (qMRIs)	193:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	1	8	theme	quantitative	209:220	arg1	qMRIs					228:232	qMRIs	228:232	qMRIs	228:232	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	12	9	contain	had	2027:2029	arg2	R2					2053:2054	R2 = 0.75 and 0.66	2053:2070	R2	2053:2054	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg2	accuracy					2043:2050	the highest accuracy	2031:2050	the highest accuracy (R2 = 0.75 and 0.66)	2031:2071	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg2	prediction-error					2084:2099	lowest prediction-error	2077:2099	lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55)	2077:2142	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg1	algorithm					2017:2025	GPR algorithm	2013:2025	GPR algorithm	2013:2025	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg2	0.66					2067:2070	0.66	2067:2070	0.66	2067:2070	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg2	2.55					2138:2141	2.55	2138:2141	2.55	2138:2141	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	9	contain	had	2027:2029	arg2	[RMSE					2120:2124	root mean squared [RMSE] = 1.34 and 2.55	2102:2141	[RMSE	2120:2124	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	6	10	theme	process	1198:1204	arg1	GPR					1218:1220	GPR	1218:1220	GPR	1218:1220	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	10	theme	process	1198:1204	arg1	regression					1206:1215	Gaussian process regression	1189:1215	Gaussian process regression (GPR)	1189:1221	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	8	11	from	densitometry	1409:1420	arg1	histology					1386:1394	quantitative histology	1373:1394	quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM)	1373:1462	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	4	12	theme	induced	685:691	arg1	lesions					703:709	surgically induced cartilage lesions	674:709	surgically induced cartilage lesions followed by treatment	674:731	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	11	13	theme	models	1742:1747	arg1	RESULTS					1713:1719	RESULTS Four	1713:1724	RESULTS Four out of the five models (RF, GB, MLP, and GPR)	1713:1770	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	5	14	theme	9.4 T	869:873	arg1	T2ρ					931:933	T2ρ	931:933	T2ρ	931:933	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	T2					908:909	T2	908:909	T2	908:909	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	T1ρ					953:955	continuous-wave T1ρ	937:955	continuous-wave T1ρ	937:955	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	T1ρ					923:925	T1ρ	923:925	T1ρ	923:925	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	sequences					892:900	A 9.4 T MRI scanner/qMRI sequences	867:900	A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation	867:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	relaxation					961:970	relaxation	961:970	relaxation	961:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	14	theme	9.4 T	869:873	arg1	T1					903:904	T1	903:904	T1	903:904	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	6	15	theme	Gaussian	1189:1196	arg1	GPR					1218:1220	GPR	1218:1220	GPR	1218:1220	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	15	theme	Gaussian	1189:1196	arg1	regression					1206:1215	Gaussian process regression	1189:1215	Gaussian process regression (GPR)	1189:1221	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	5	16	dep	TRAFF	998:1002	arg1	maps					1006:1009	maps	1006:1009	maps	1006:1009	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	11	17	theme	significant	1852:1862	arg1	correlations					1864:1875	strong significant correlations	1845:1875	strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD)	1845:2010	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	T2ρ					931:933	T2ρ	931:933	T2ρ	931:933	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	T2					908:909	T2	908:909	T2	908:909	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	T1ρ					953:955	continuous-wave T1ρ	937:955	continuous-wave T1ρ	937:955	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	T1ρ					923:925	T1ρ	923:925	T1ρ	923:925	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	sequences					892:900	A 9.4 T MRI scanner/qMRI sequences	867:900	A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation	867:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	relaxation					961:970	relaxation	961:970	relaxation	961:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	18	theme	scanner/qMRI	879:890	arg1	T1					903:904	T1	903:904	T1	903:904	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	14	19	dep	Stage	2429:2433	arg1	EFFICACY					2419:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY: Stage 2.					
35861162	8	20	theme	polarized	1431:1439	arg1	PLM					1459:1461	PLM	1459:1461	PLM	1459:1461	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	8	20	theme	polarized	1431:1439	arg1	microscopy					1447:1456	polarized light microscopy	1431:1456	polarized light microscopy (PLM)	1431:1462	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	4	21	theme	data	777:780	arg1	points					782:787	1600 data points	772:787	1600 data points	772:787	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	4	21	theme	data	777:780	arg1	%					819:819	90%	817:819	90% for train validation	817:840	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	4	21	theme	data	777:780	arg1	%					802:802	10%	800:802	10% for test	800:811	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	13	22	theme	proteoglycan	2370:2381	arg1	content					2383:2389	proteoglycan content	2370:2389	proteoglycan content	2370:2389	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	11	23	theme	reference	1889:1897	arg1	measurements					1899:1910	the reference measurements	1885:1910	the reference measurements	1885:1910	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	5	24	theme	continuous-wave	937:951	arg1	T1ρ					953:955	continuous-wave T1ρ	937:955	continuous-wave T1ρ	937:955	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	24	theme	continuous-wave	937:951	arg1	sequences					892:900	A 9.4 T MRI scanner/qMRI sequences	867:900	A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation	867:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	6	25	theme	machine	1028:1034	arg1	models					1056:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	3	26	theme	STUDY	522:526	arg1	model					555:559	STUDY TYPE Retrospective, animal model	522:559	model	555:559	STUDY TYPE Retrospective, animal model.					
35861162	4	27	theme	healthy	743:749	arg1	controls					751:758	three healthy controls	737:758	three healthy controls	737:758	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	0	28	theme	Proteoglycan	62:73	arg1	Content					75:81	Proteoglycan Content	62:81	Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage	62:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	11	29	dep	models	1742:1747	arg1	RF					1750:1751	RF	1750:1751	RF	1750:1751	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	11	29	dep	models	1742:1747	arg1	GPR					1767:1769	GPR	1767:1769	GPR	1767:1769	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	11	29	dep	models	1742:1747	arg1	out					1726:1728	out	1726:1728	out	1726:1728	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	11	29	dep	models	1742:1747	arg1	GB					1754:1755	GB	1754:1755	GB	1754:1755	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	11	29	dep	models	1742:1747	arg1	MLP					1758:1760	MLP	1758:1760	MLP	1758:1760	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	11	29	dep	models	1742:1747	arg1	models					1742:1747	the five models	1733:1747	the five models (RF, GB, MLP, and GPR)	1733:1770	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	9	30	theme	STATISTICAL	1479:1489	arg1	TESTS					1491:1495	STATISTICAL TESTS	1479:1495	STATISTICAL TESTS Normality	1479:1505	STATISTICAL TESTS Normality was tested using Shapiro-Wilk test, and association between predicted and measured values was evaluated using Spearman's Rho test.					
35861162	6	31	theme	ASSESSMENT	1012:1021	arg1	models					1056:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	11	32	dep	properties	1943:1952	arg1	Rho = 0.72-0.88					1966:1980	Spearman's Rho = 0.72-0.88	1955:1980	Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD	1955:2009	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	7	33	used	used	1254:1257	arg2	cross-validation					1233:1248	A nested cross-validation	1224:1248	A nested cross-validation	1224:1248	A nested cross-validation was used for performance evaluation.					
35861162	0	34	theme	Quantitative	104:115	arg1	MRI					117:119	Multiparametric Quantitative MRI	88:119	Multiparametric Quantitative MRI in Articular Cartilage	88:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	5	35	theme	fictitious	980:989	arg1	TRAFF					998:1002	a fictitious field (TRAFF ) maps	978:1009	a fictitious field (TRAFF ) maps	978:1009	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	1	36	theme	Machine	156:162	arg1	models					173:178	BACKGROUND Machine learning models	145:178	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs)	145:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	13	37	theme	collagen	2338:2345	arg1	orientation					2353:2363	collagen fiber orientation	2338:2363	collagen fiber orientation	2338:2363	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	12	38	theme	lowest	2077:2082	arg1	[RMSE					2120:2124	root mean squared [RMSE] = 1.34 and 2.55	2102:2141	[RMSE	2120:2124	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	38	theme	lowest	2077:2082	arg1	prediction-error					2084:2099	lowest prediction-error	2077:2099	lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55)	2077:2142	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	38	theme	lowest	2077:2082	arg1	2.55					2138:2141	2.55	2138:2141	2.55	2138:2141	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	3	39	dep	model	555:559	arg1	animal					548:553	STUDY TYPE Retrospective, animal model	522:559	animal	548:553	STUDY TYPE Retrospective, animal model.					
35861162	2	40	theme	proteoglycan	500:511	arg1	content					513:519	proteoglycan content	500:519	proteoglycan content	500:519	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	2	41	dep	performance	364:374	arg1	the					360:362	the	360:362	the	360:362	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	0	42	theme	Machine	0:6	arg1	Learning					8:15	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage	0:142	Learning	8:15	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	11	43	dep	accuracy	1785:1792	arg1	R2					1795:1796	R2 = 0.68-0.75	1795:1808	R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD	1795:1837	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	2	44	theme	orientation	484:494	arg1	assessment					455:464	noninvasive assessment	443:464	noninvasive assessment of collagen fiber orientation and proteoglycan content	443:519	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	12	45	theme	mean	2107:2110	arg1	[RMSE					2120:2124	root mean squared [RMSE] = 1.34 and 2.55	2102:2141	[RMSE	2120:2124	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	45	theme	mean	2107:2110	arg1	prediction-error					2084:2099	lowest prediction-error	2077:2099	lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55)	2077:2142	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	2	46	theme	collagen	469:476	arg1	orientation					484:494	collagen fiber orientation	469:494	collagen fiber orientation	469:494	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	1	47	theme	articular	322:330	arg1	cartilage					332:340	articular cartilage	322:340	articular cartilage	322:340	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	0	48	theme	Collagen	31:38	arg1	Orientation					46:56	Collagen Fiber Orientation	31:56	Collagen Fiber Orientation	31:56	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	13	49	theme	cartilage	2264:2272	arg1	features					2303:2310	cartilage compositional and structural features	2264:2310	cartilage compositional and structural features	2264:2310	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	6	50	theme	regression	1045:1054	arg1	models					1056:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	4	51	theme	open-source	578:588	arg1	dataset					607:613	An open-source single slice MRI dataset	575:613	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	8	52	theme	quantitative	1373:1384	arg1	histology					1386:1394	quantitative histology	1373:1394	quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM)	1373:1462	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	0	53	theme	Orientation	46:56	arg1	Prediction					17:26	Prediction	17:26	Prediction of Collagen Fiber Orientation	17:56	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	13	54	with	combination	2215:2225	arg1	models					2243:2248	regression models	2232:2248	regression models	2232:2248	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	9	55	theme	measured	1581:1588	arg1	values					1590:1595	measured values	1581:1595	measured values	1581:1595	STATISTICAL TESTS Normality was tested using Shapiro-Wilk test, and association between predicted and measured values was evaluated using Spearman's Rho test.					
35861162	7	56	theme	nested	1226:1231	arg1	cross-validation					1233:1248	A nested cross-validation	1224:1248	A nested cross-validation	1224:1248	A nested cross-validation was used for performance evaluation.					
35861162	4	57	theme	slice	597:601	arg1	dataset					607:613	An open-source single slice MRI dataset	575:613	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	1	58	contain	have	235:238	arg1	models					173:178	BACKGROUND Machine learning models	145:178	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs)	145:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	1	58	contain	have	235:238	arg2	potential					244:252	the potential to provide valuable information about the structural composition of articular cartilage	240:340	the potential to provide valuable information about the structural composition of articular cartilage	240:340	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	3	59	theme	Retrospective	533:545	arg1	model					555:559	STUDY TYPE Retrospective, animal model	522:559	model	555:559	STUDY TYPE Retrospective, animal model.					
35861162	14	60	theme	TECHNICAL	2409:2417	arg1	EFFICACY					2419:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY: Stage 2.					
35861162	13	61	theme	regression	2232:2241	arg1	models					2243:2248	regression models	2232:2248	regression models	2232:2248	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	12	62	theme	root	2102:2105	arg1	[RMSE					2120:2124	root mean squared [RMSE] = 1.34 and 2.55	2102:2141	[RMSE	2120:2124	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	62	theme	root	2102:2105	arg1	prediction-error					2084:2099	lowest prediction-error	2077:2099	lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55)	2077:2142	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	6	63	theme	vector	1107:1112	arg1	regression					1114:1123	support vector regression	1099:1123	support vector regression (SVR)	1099:1129	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	63	theme	vector	1107:1112	arg1	SVR					1126:1128	SVR	1126:1128	SVR	1126:1128	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	4	64	theme	ponies	655:660	arg1	samples					632:638	20 samples	629:638	20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	629:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	4	65	theme	train	825:829	arg1	validation					831:840	train validation	825:840	train validation	825:840	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	10	66	theme	statistical	1687:1697	arg1	significance					1699:1710	statistical significance	1687:1710	statistical significance	1687:1710	A P-value of 0.05 was considered as the limit of statistical significance.					
35861162	14	67	theme	LEVEL	2401:2405	arg1	EFFICACY					2419:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY	2392:2426	EVIDENCE LEVEL 2 TECHNICAL EFFICACY: Stage 2.					
35861162	13	68	from	qMRIs	2206:2210	arg1	combination					2215:2225	combination	2215:2225	combination with regression models	2215:2248	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	11	69	theme	high	1780:1783	arg1	accuracy					1785:1792	high accuracy	1780:1792	high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD)	1780:1838	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	5	70	dep	sequences	892:900	arg1	T2					908:909	T2	908:909	T2	908:909	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	70	dep	sequences	892:900	arg1	T1ρ					953:955	continuous-wave T1ρ	937:955	continuous-wave T1ρ	937:955	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	70	dep	sequences	892:900	arg1	T1ρ					923:925	T1ρ	923:925	T1ρ	923:925	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	70	dep	sequences	892:900	arg1	sequences					892:900	A 9.4 T MRI scanner/qMRI sequences	867:900	A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation	867:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	70	dep	sequences	892:900	arg1	relaxation					961:970	relaxation	961:970	relaxation	961:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	70	dep	sequences	892:900	arg1	T1					903:904	T1	903:904	T1	903:904	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	11	71	theme	predicted	1916:1924	arg1	properties					1943:1952	predicted cartilage matrix properties	1916:1952	predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD)	1916:2010	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	1	72	theme	multiparametric	193:207	arg1	MRIs					222:225	multiparametric quantitative MRIs	193:225	multiparametric quantitative MRIs (qMRIs)	193:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	1	72	theme	multiparametric	193:207	arg1	qMRIs					228:232	qMRIs	228:232	qMRIs	228:232	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	13	73	theme	Multiparametric	2190:2204	arg1	qMRIs					2206:2210	Multiparametric qMRIs	2190:2210	Multiparametric qMRIs in combination with regression models	2190:2248	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	6	74	theme	gradient	1132:1139	arg1	GB					1151:1152	GB	1151:1152	GB	1151:1152	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	74	theme	gradient	1132:1139	arg1	boosting					1141:1148	gradient boosting	1132:1148	gradient boosting (GB)	1132:1153	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	12	75	theme	highest	2035:2041	arg1	R2					2053:2054	R2 = 0.75 and 0.66	2053:2070	R2	2053:2054	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	75	theme	highest	2035:2041	arg1	0.66					2067:2070	0.66	2067:2070	0.66	2067:2070	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	75	theme	highest	2035:2041	arg1	accuracy					2043:2050	the highest accuracy	2031:2050	the highest accuracy (R2 = 0.75 and 0.66)	2031:2071	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	11	76	theme	matrix	1936:1941	arg1	properties					1943:1952	predicted cartilage matrix properties	1916:1952	predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD)	1916:2010	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	2	77	theme	models	412:417	arg1	feasibility					380:390	feasibility	380:390	feasibility	380:390	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	2	77	theme	models	412:417	arg1	performance					364:374	performance	364:374	performance	364:374	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	11	78	theme	strong	1845:1850	arg1	correlations					1864:1875	strong significant correlations	1845:1875	strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD)	1845:2010	RESULTS Four out of the five models (RF, GB, MLP, and GPR) yielded high accuracy (R2 = 0.68-0.75 for PLM and 0.62-0.66 for DD), and strong significant correlations between the reference measurements and predicted cartilage matrix properties (Spearman's Rho = 0.72-0.88 for PLM and 0.61-0.83 for DD).					
35861162	5	79	theme	MRI	875:877	arg1	T2ρ					931:933	T2ρ	931:933	T2ρ	931:933	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	T2					908:909	T2	908:909	T2	908:909	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	T1ρ					953:955	continuous-wave T1ρ	937:955	continuous-wave T1ρ	937:955	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	T1ρ					923:925	T1ρ	923:925	T1ρ	923:925	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	sequences					892:900	A 9.4 T MRI scanner/qMRI sequences	867:900	A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation	867:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	relaxation					961:970	relaxation	961:970	relaxation	961:970	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	5	79	theme	MRI	875:877	arg1	T1					903:904	T1	903:904	T1	903:904	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	4	80	theme	cartilage	693:701	arg1	lesions					703:709	surgically induced cartilage lesions	674:709	surgically induced cartilage lesions followed by treatment	674:731	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	13	81	theme	fiber	2347:2351	arg1	orientation					2353:2363	collagen fiber orientation	2338:2363	collagen fiber orientation	2338:2363	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	8	82	theme	light	1441:1445	arg1	PLM					1459:1461	PLM	1459:1461	PLM	1459:1461	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	8	82	theme	light	1441:1445	arg1	microscopy					1447:1456	polarized light microscopy	1431:1456	polarized light microscopy (PLM)	1431:1462	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	1	83	theme	BACKGROUND	145:154	arg1	models					173:178	BACKGROUND Machine learning models	145:178	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs)	145:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	6	84	theme	learning	1036:1043	arg1	models					1056:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models	1012:1061	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	0	85	from	MRI	117:119	arg1	Cartilage					134:142	Articular Cartilage	124:142	Articular Cartilage	124:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	0	85	from	MRI	117:119	arg1	Learning					8:15	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage	0:142	Learning	8:15	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	0	85	from	MRI	117:119	arg1	Content					75:81	Proteoglycan Content	62:81	Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage	62:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	4	86	dep	ponies	655:660	arg1	controls					751:758	three healthy controls	737:758	three healthy controls	737:758	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	4	86	dep	ponies	655:660	arg1	seven					663:667	seven	663:667	seven	663:667	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	1	87	theme	learning	164:171	arg1	models					173:178	BACKGROUND Machine learning models	145:178	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs)	145:233	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	4	88	theme	ANIMAL	562:567	arg1	MODEL					569:573	ANIMAL MODEL	562:573	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	6	89	theme	multilayer	1156:1165	arg1	MLP					1179:1181	MLP	1179:1181	MLP	1179:1181	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	89	theme	multilayer	1156:1165	arg1	perceptron					1167:1176	multilayer perceptron	1156:1176	multilayer perceptron (MLP)	1156:1182	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	8	90	from	microscopy	1447:1456	arg1	histology					1386:1394	quantitative histology	1373:1394	quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM)	1373:1462	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	0	91	theme	Multiparametric	88:102	arg1	MRI					117:119	Multiparametric Quantitative MRI	88:119	Multiparametric Quantitative MRI in Articular Cartilage	88:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	9	92	theme	TESTS	1491:1495	arg1	Normality					1497:1505	STATISTICAL TESTS Normality	1479:1505	STATISTICAL TESTS Normality	1479:1505	STATISTICAL TESTS Normality was tested using Shapiro-Wilk test, and association between predicted and measured values was evaluated using Spearman's Rho test.					
35861162	13	93	theme	higher	2318:2323	arg1	accuracy					2325:2332	higher accuracy	2318:2332	higher accuracy for collagen fiber orientation than proteoglycan content	2318:2389	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	12	94	theme	squared	2112:2118	arg1	[RMSE					2120:2124	root mean squared [RMSE] = 1.34 and 2.55	2102:2141	[RMSE	2120:2124	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	12	94	theme	squared	2112:2118	arg1	prediction-error					2084:2099	lowest prediction-error	2077:2099	lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55)	2077:2142	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	0	95	theme	Articular	124:132	arg1	Cartilage					134:142	Articular Cartilage	124:142	Articular Cartilage	124:142	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	5	96	theme	field	991:995	arg1	TRAFF					998:1002	a fictitious field (TRAFF ) maps	978:1009	a fictitious field (TRAFF ) maps	978:1009	FIELD STRENGTH/SEQUENCE A 9.4 T MRI scanner/qMRI sequences: T1 , T2 , adiabatic T1ρ and T2ρ , continuous-wave T1ρ and relaxation along a fictitious field (TRAFF ) maps.					
35861162	8	97	theme	proteoglycan	1302:1313	arg1	content					1315:1321	proteoglycan content	1302:1321	proteoglycan content	1302:1321	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	13	98	theme	structural	2292:2301	arg1	features					2303:2310	cartilage compositional and structural features	2264:2310	cartilage compositional and structural features	2264:2310	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	7	99	theme	performance	1263:1273	arg1	evaluation					1275:1284	performance evaluation	1263:1284	performance evaluation	1263:1284	A nested cross-validation was used for performance evaluation.					
35861162	2	100	theme	fiber	478:482	arg1	orientation					484:494	collagen fiber orientation	469:494	collagen fiber orientation	469:494	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	8	101	theme	fiber	1336:1340	arg1	orientation					1342:1352	collagen fiber orientation	1327:1352	collagen fiber orientation	1327:1352	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	3	102	theme	TYPE	528:531	arg1	model					555:559	STUDY TYPE Retrospective, animal model	522:559	model	555:559	STUDY TYPE Retrospective, animal model.					
35861162	0	103	theme	Fiber	40:44	arg1	Orientation					46:56	Collagen Fiber Orientation	31:56	Collagen Fiber Orientation	31:56	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	1	104	theme	cartilage	332:340	arg1	composition					307:317	the structural composition	292:317	the structural composition of articular cartilage	292:340	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
35861162	13	105	theme	DATA	2174:2177	arg1	CONCLUSION					2179:2188	DATA CONCLUSION	2174:2188	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.	2174:2390	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	4	106	theme	single	590:595	arg1	dataset					607:613	An open-source single slice MRI dataset	575:613	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	2	107	theme	noninvasive	443:453	arg1	assessment					455:464	noninvasive assessment	443:464	noninvasive assessment of collagen fiber orientation and proteoglycan content	443:519	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	4	108	dep	MODEL	569:573	arg1	dataset					607:613	An open-source single slice MRI dataset	575:613	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	13	109	theme	compositional	2274:2286	arg1	features					2303:2310	cartilage compositional and structural features	2264:2310	cartilage compositional and structural features	2264:2310	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	2	110	theme	content	513:519	arg1	assessment					455:464	noninvasive assessment	443:464	noninvasive assessment of collagen fiber orientation and proteoglycan content	443:519	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	4	111	theme	MRI	603:605	arg1	dataset					607:613	An open-source single slice MRI dataset	575:613	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls)	562:759	ANIMAL MODEL An open-source single slice MRI dataset obtained from 20 samples of 10 Shetland ponies (seven with surgically induced cartilage lesions followed by treatment and three healthy controls) yielded to 1600 data points, including 10% for test and 90% for train validation.					
35861162	9	112	theme	Shapiro-Wilk	1524:1535	arg1	test					1537:1540	Shapiro-Wilk test	1524:1540	Shapiro-Wilk test	1524:1540	STATISTICAL TESTS Normality was tested using Shapiro-Wilk test, and association between predicted and measured values was evaluated using Spearman's Rho test.					
35861162	13	113	dep	CONCLUSION	2179:2188	arg1	determine					2254:2262	determine	2254:2262	determine	2254:2262	DATA CONCLUSION Multiparametric qMRIs in combination with regression models can determine cartilage compositional and structural features, with higher accuracy for collagen fiber orientation than proteoglycan content.					
35861162	10	114	theme	0.05	1651:1654	arg1	limit					1678:1682	the limit	1674:1682	the limit of statistical significance	1674:1710	A P-value of 0.05 was considered as the limit of statistical significance.					
35861162	10	114	theme	0.05	1651:1654	arg1	P-value					1640:1646	A P-value	1638:1646	A P-value of 0.05	1638:1654	A P-value of 0.05 was considered as the limit of statistical significance.					
35861162	12	115	theme	GPR	2013:2015	arg1	algorithm					2017:2025	GPR algorithm	2013:2025	GPR algorithm	2013:2025	GPR algorithm had the highest accuracy (R2 = 0.75 and 0.66) and lowest prediction-error (root mean squared [RMSE] = 1.34 and 2.55) for PLM and DD, respectively.					
35861162	0	116	dep	Learning	8:15	arg1	Prediction					17:26	Prediction	17:26	Prediction of Collagen Fiber Orientation	17:56	Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage.					
35861162	6	117	theme	support	1099:1105	arg1	regression					1114:1123	support vector regression	1099:1123	support vector regression (SVR)	1099:1129	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	6	117	theme	support	1099:1105	arg1	SVR					1126:1128	SVR	1126:1128	SVR	1126:1128	ASSESSMENT Five machine learning regression models were developed: random forest (RF), support vector regression (SVR), gradient boosting (GB), multilayer perceptron (MLP), and Gaussian process regression (GPR).					
35861162	8	118	theme	digital	1401:1407	arg1	DD					1423:1424	DD	1423:1424	DD	1423:1424	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	8	118	theme	digital	1401:1407	arg1	densitometry					1409:1420	digital densitometry	1401:1420	digital densitometry (DD)	1401:1425	For reference, proteoglycan content and collagen fiber orientation were determined by quantitative histology from digital densitometry (DD) and polarized light microscopy (PLM), respectively.					
35861162	2	119	theme	learning	403:410	arg1	models					412:417	machine learning models	395:417	machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content	395:519	PURPOSE To study the performance and feasibility of machine learning models combined with qMRIs for noninvasive assessment of collagen fiber orientation and proteoglycan content.					
35861162	1	120	theme	valuable	265:272	arg1	information					274:284	valuable information	265:284	valuable information about the structural composition of articular cartilage	265:340	BACKGROUND Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage.					
36585891	11	0	from	impact	1721:1726	arg1	changes					1735:1741	the changes	1731:1741	the changes of the storage modulus in all grades of IDD	1731:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	1	1	from	changes	214:220	arg1	composition					255:265	the intervertebral disc (IVD) composition	225:265	the intervertebral disc (IVD) composition	225:265	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	1	1	from	changes	214:220	arg1	properties					298:307	the resulting viscoelastic properties	271:307	the resulting viscoelastic properties	271:307	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	6	2	from	increase	1010:1017	arg1	proteoglycan					1073:1084	proteoglycan	1073:1084	proteoglycan	1073:1084	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	2	from	increase	1010:1017	arg1	ratio					1039:1043	the crosslinking ratio	1022:1043	the crosslinking ratio in collagen	1022:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	2	3	theme	severe	319:324	arg1	condition					326:334	a severe condition	317:334	a severe condition because it decreases the disc's ability to resist mechanical loads	317:401	IDD is a severe condition because it decreases the disc's ability to resist mechanical loads.					
36585891	2	3	theme	severe	319:324	arg1	IDD					310:312	IDD	310:312	IDD	310:312	IDD is a severe condition because it decreases the disc's ability to resist mechanical loads.					
36585891	1	4	theme	intervertebral	229:242	arg1	composition					255:265	the intervertebral disc (IVD) composition	225:265	the intervertebral disc (IVD) composition	225:265	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	12	5	theme	tissue	1911:1916	arg1	behavior					1918:1925	tissue behavior	1911:1925	tissue behavior	1911:1925	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	9	6	theme	storage	1575:1581	arg1	modulus					1583:1589	the storage modulus	1571:1589	the storage modulus	1571:1589	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	1	7	theme	disc	168:171	arg1	degeneration					173:184	Intervertebral disc degeneration	153:184	Intervertebral disc degeneration (IDD)	153:190	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	1	7	theme	disc	168:171	arg1	IDD					187:189	IDD	187:189	IDD	187:189	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	6	8	theme	disc	1157:1160	arg1	damage					1162:1167	the disc damage	1153:1167	the disc damage in the NP	1153:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	3	9	theme	pulposus	534:541	arg1	properties					508:517	the viscoelastic properties	491:517	the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood	491:575	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	9	10	contain	have	1512:1515	arg2	similarities					1517:1528	similarities	1517:1528	similarities in the changes of Amide I and III	1517:1562	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	9	10	contain	have	1512:1515	arg1	grades					1494:1499	grades III and IV	1494:1510	grades	1494:1499	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	9	10	contain	have	1512:1515	arg1	IV					1509:1510	IV	1509:1510	IV	1509:1510	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	11	11	theme	proteoglycan	1692:1703	arg1	Reduction					1679:1687	Reduction	1679:1687	Reduction of proteoglycan	1679:1703	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	12	12	theme	various	1850:1856	arg1	degrees					1858:1864	various degrees	1850:1864	various degrees of degeneration	1850:1880	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	5	13	theme	degenerative	797:808	arg1	severity					810:817	the degenerative severity	793:817	the degenerative severity of IVD	793:824	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	4	14	theme	subtle	690:695	arg1	changes					697:703	subtle changes	690:703	subtle changes in the biochemical makeup of the NP	690:739	This study employed a system integrating nanoindentation with Raman spectrometry to correlate biomechanics with subtle changes in the biochemical makeup of the NP.					
36585891	0	15	theme	pulposus	143:150	arg1	properties					117:126	biomechanical properties	103:126	biomechanical properties of the nucleus pulposus	103:150	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	0	15	theme	pulposus	143:150	arg1	imaging					72:78	magnetic resonance imaging	53:78	magnetic resonance imaging	53:78	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	0	15	theme	pulposus	143:150	arg1	content					90:96	chemical content	81:96	chemical content	81:96	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	3	16	theme	viscoelastic	495:506	arg1	properties					508:517	the viscoelastic properties	491:517	the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood	491:575	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	4	17	theme	Raman	640:644	arg1	spectrometry					646:657	Raman spectrometry	640:657	Raman spectrometry	640:657	This study employed a system integrating nanoindentation with Raman spectrometry to correlate biomechanics with subtle changes in the biochemical makeup of the NP.					
36585891	0	18	theme	resonance	62:70	arg1	imaging					72:78	magnetic resonance imaging	53:78	magnetic resonance imaging	53:78	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	5	19	theme	resonance	853:861	arg1	MRI					872:874	MRI	872:874	MRI	872:874	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	5	19	theme	resonance	853:861	arg1	imaging					863:869	magnetic resonance imaging	844:869	magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis	844:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	2	20	dep	condition	326:334	arg1	decreases					347:355	decreases	347:355	decreases the disc's ability to resist mechanical loads	347:401	IDD is a severe condition because it decreases the disc's ability to resist mechanical loads.					
36585891	12	21	theme	IVD	1828:1830	arg1	micromechanics					1832:1845	IVD micromechanics	1828:1845	IVD micromechanics at various degrees of degeneration	1828:1880	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	9	22	theme	discs	1477:1481	arg1	correlation					1447:1457	The correlation	1443:1457	The correlation of the individual discs	1443:1481	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	4	23	theme	NP	738:739	arg1	makeup					724:729	the biochemical makeup	708:729	the biochemical makeup of the NP	708:739	This study employed a system integrating nanoindentation with Raman spectrometry to correlate biomechanics with subtle changes in the biochemical makeup of the NP.					
36585891	6	24	from	build-up	1093:1100	arg1	proteoglycan					1073:1084	proteoglycan	1073:1084	proteoglycan	1073:1084	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	24	from	build-up	1093:1100	arg1	ratio					1039:1043	the crosslinking ratio	1022:1043	the crosslinking ratio in collagen	1022:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	5	25	theme	degenerative	921:932	arg1	spondylolisthesis					934:950	degenerative spondylolisthesis	921:950	degenerative spondylolisthesis	921:950	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	11	26	theme	IDD	1783:1785	arg1	grades					1773:1778	all grades	1769:1778	all grades of IDD	1769:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	1	27	theme	IVD	250:252	arg1	composition					255:265	the intervertebral disc (IVD) composition	225:265	the intervertebral disc (IVD) composition	225:265	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	5	28	theme	different	880:888	arg1	patients					890:897	different patients	880:897	different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis	880:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	7	29	theme	increasing	1238:1247	arg1	degeneration					1254:1265	the increasing disc degeneration	1234:1265	the increasing disc degeneration	1234:1265	Assessment of mechanical characteristics reveals that the increasing disc degeneration makes the NP lose its elasticity, becoming more viscous.					
36585891	4	30	theme	biochemical	712:722	arg1	makeup					724:729	the biochemical makeup	708:729	the biochemical makeup of the NP	708:739	This study employed a system integrating nanoindentation with Raman spectrometry to correlate biomechanics with subtle changes in the biochemical makeup of the NP.					
36585891	2	31	theme	mechanical	386:395	arg1	loads					397:401	mechanical loads	386:401	mechanical loads	386:401	IDD is a severe condition because it decreases the disc's ability to resist mechanical loads.					
36585891	0	32	theme	stage	32:36	arg1	Correlation					0:10	Correlation	0:10	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.	0:151	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	7	33	theme	characteristics	1205:1219	arg1	Assessment					1180:1189	Assessment	1180:1189	Assessment of mechanical characteristics	1180:1219	Assessment of mechanical characteristics reveals that the increasing disc degeneration makes the NP lose its elasticity, becoming more viscous.					
36585891	11	34	theme	storage	1750:1756	arg1	modulus					1758:1764	the storage modulus	1746:1764	the storage modulus	1746:1764	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	1	35	theme	viscoelastic	285:296	arg1	properties					298:307	the resulting viscoelastic properties	271:307	the resulting viscoelastic properties	271:307	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	6	36	from	reduction	1060:1068	arg1	proteoglycan					1073:1084	proteoglycan	1073:1084	proteoglycan	1073:1084	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	36	from	reduction	1060:1068	arg1	ratio					1039:1043	the crosslinking ratio	1022:1043	the crosslinking ratio in collagen	1022:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	11	37	contain	has	1705:1707	arg1	Reduction					1679:1687	Reduction	1679:1687	Reduction of proteoglycan	1679:1703	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	11	37	contain	has	1705:1707	arg2	impact					1721:1726	the highest impact	1709:1726	the highest impact on the changes of the storage modulus in all grades of IDD	1709:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	9	38	theme	I	1554:1554	arg1	changes					1537:1543	the changes	1533:1543	the changes of Amide I and III	1533:1562	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	6	39	from	damage	1162:1167	arg1	NP					1176:1177	the NP	1172:1177	the NP	1172:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	9	40	theme	III	1560:1562	arg1	changes					1537:1543	the changes	1533:1543	the changes of Amide I and III	1533:1562	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	6	41	theme	crosslinking	1026:1037	arg1	ratio					1039:1043	the crosslinking ratio	1022:1043	the crosslinking ratio in collagen	1022:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	10	42	theme	storage	1662:1668	arg1	modulus					1670:1676	the storage modulus	1658:1676	the storage modulus	1658:1676	In contrast, grades IV and V correlate with mineralization toward the storage modulus.					
36585891	1	43	theme	disc	244:247	arg1	composition					255:265	the intervertebral disc (IVD) composition	225:265	the intervertebral disc (IVD) composition	225:265	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	11	44	from	changes	1735:1741	arg1	grades					1773:1778	all grades	1769:1778	all grades of IDD	1769:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	6	45	theme	minerals	1105:1112	arg1	increase					1010:1017	an increase	1007:1017	an increase in the crosslinking ratio in collagen	1007:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	45	theme	minerals	1105:1112	arg1	reduction					1060:1068	a reduction	1058:1068	a reduction in proteoglycan	1058:1084	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	45	theme	minerals	1105:1112	arg1	build-up					1093:1100	a build-up	1091:1100	a build-up of minerals upon the rise in the severity level of the disc damage in the NP	1091:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	3	46	theme	cellular	447:454	arg1	level					456:460	the cellular level	443:460	the cellular level	443:460	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	3	47	from	changes	480:486	arg1	properties					508:517	the viscoelastic properties	491:517	the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood	491:575	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	1	48	theme	Intervertebral	153:166	arg1	degeneration					173:184	Intervertebral disc degeneration	153:184	Intervertebral disc degeneration (IDD)	153:190	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	1	48	theme	Intervertebral	153:166	arg1	IDD					187:189	IDD	187:189	IDD	187:189	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	12	49	theme	behavior	1918:1925	arg1	understanding					1894:1906	our understanding	1890:1906	our understanding of tissue behavior	1890:1925	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	5	50	with	patients	890:897	arg1	stenosis					911:918	spinal stenosis	904:918	spinal stenosis	904:918	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	5	50	with	patients	890:897	arg1	spondylolisthesis					934:950	degenerative spondylolisthesis	921:950	degenerative spondylolisthesis	921:950	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	5	50	with	patients	890:897	arg1	scoliosis					970:978	degenerative scoliosis	957:978	degenerative scoliosis	957:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	6	51	theme	damage	1162:1167	arg1	level					1144:1148	the severity level	1131:1148	the severity level of the disc damage in the NP	1131:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	3	52	theme	nucleus	526:532	arg1	NP					544:545	NP	544:545	NP	544:545	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	3	52	theme	nucleus	526:532	arg1	pulposus					534:541	the nucleus pulposus	522:541	the nucleus pulposus (NP)	522:546	Our research aims to understand IDD at the cellular level, specifically the changes in the viscoelastic properties of the nucleus pulposus (NP), which are poorly understood.					
36585891	5	53	theme	IVD	822:824	arg1	severity					810:817	the degenerative severity	793:817	the degenerative severity of IVD	793:824	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	12	54	theme	degeneration	1869:1880	arg1	degrees					1858:1864	various degrees	1850:1864	various degrees of degeneration	1850:1880	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	11	55	theme	highest	1713:1719	arg1	impact					1721:1726	the highest impact	1709:1726	the highest impact on the changes of the storage modulus in all grades of IDD	1709:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	0	56	theme	biomechanical	103:115	arg1	properties					117:126	biomechanical properties	103:126	biomechanical properties of the nucleus pulposus	103:150	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	8	57	theme	weight-bearing	1378:1391	arg1	ability					1393:1399	weight-bearing ability	1378:1399	weight-bearing ability	1378:1399	This shows that the tissue undergoes abnormalities in weight-bearing ability, which contributes to spinal instability.					
36585891	0	58	theme	nucleus	135:141	arg1	pulposus					143:150	the nucleus pulposus	131:150	the nucleus pulposus	131:150	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	6	59	theme	severity	1135:1142	arg1	level					1144:1148	the severity level	1131:1148	the severity level of the disc damage in the NP	1131:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	60	from	level	1144:1148	arg1	NP					1176:1177	the NP	1172:1177	the NP	1172:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	0	61	with	Correlation	0:10	arg1	properties					117:126	biomechanical properties	103:126	biomechanical properties of the nucleus pulposus	103:150	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	0	61	with	Correlation	0:10	arg1	imaging					72:78	magnetic resonance imaging	53:78	magnetic resonance imaging	53:78	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	0	61	with	Correlation	0:10	arg1	content					90:96	chemical content	81:96	chemical content	81:96	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	9	62	theme	individual	1466:1475	arg1	discs					1477:1481	the individual discs	1462:1481	the individual discs	1462:1481	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	12	63	theme	tissue	1999:2004	arg1	engineering					2006:2016	tissue engineering	1999:2016	tissue engineering	1999:2016	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	0	64	theme	magnetic	53:60	arg1	imaging					72:78	magnetic resonance imaging	53:78	magnetic resonance imaging	53:78	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	8	65	theme	spinal	1423:1428	arg1	instability					1430:1440	spinal instability	1423:1440	spinal instability	1423:1440	This shows that the tissue undergoes abnormalities in weight-bearing ability, which contributes to spinal instability.					
36585891	12	66	theme	clinical	1962:1969	arg1	diagnostics					1971:1981	clinical diagnostics	1962:1981	clinical diagnostics	1962:1981	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	6	67	from	rise	1123:1126	arg1	level					1144:1148	the severity level	1131:1148	the severity level of the disc damage in the NP	1131:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	8	68	from	abnormalities	1361:1373	arg1	ability					1393:1399	weight-bearing ability	1378:1399	weight-bearing ability	1378:1399	This shows that the tissue undergoes abnormalities in weight-bearing ability, which contributes to spinal instability.					
36585891	5	69	theme	magnetic	844:851	arg1	MRI					872:874	MRI	872:874	MRI	872:874	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	5	69	theme	magnetic	844:851	arg1	imaging					863:869	magnetic resonance imaging	844:869	magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis	844:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	0	70	theme	chemical	81:88	arg1	content					90:96	chemical content	81:96	chemical content	81:96	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	5	71	theme	spinal	904:909	arg1	stenosis					911:918	spinal stenosis	904:918	spinal stenosis	904:918	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	7	72	theme	disc	1249:1252	arg1	degeneration					1254:1265	the increasing disc degeneration	1234:1265	the increasing disc degeneration	1234:1265	Assessment of mechanical characteristics reveals that the increasing disc degeneration makes the NP lose its elasticity, becoming more viscous.					
36585891	12	73	theme	compositional	1799:1811	arg1	alterations					1813:1823	compositional alterations	1799:1823	compositional alterations	1799:1823	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	0	74	theme	degenerative	19:30	arg1	stage					32:36	the degenerative stage	15:36	the degenerative stage of a disc	15:46	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	4	75	from	changes	697:703	arg1	makeup					724:729	the biochemical makeup	708:729	the biochemical makeup of the NP	708:739	This study employed a system integrating nanoindentation with Raman spectrometry to correlate biomechanics with subtle changes in the biochemical makeup of the NP.					
36585891	5	76	theme	patients	890:897	arg1	MRI					872:874	MRI	872:874	MRI	872:874	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	5	76	theme	patients	890:897	arg1	imaging					863:869	magnetic resonance imaging	844:869	magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis	844:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	10	77	dep	grades	1605:1610	arg1	grades					1605:1610	grades IV and V	1605:1619	grades IV and V	1605:1619	In contrast, grades IV and V correlate with mineralization toward the storage modulus.					
36585891	10	77	dep	grades	1605:1610	arg1	V					1619:1619	V	1619:1619	V	1619:1619	In contrast, grades IV and V correlate with mineralization toward the storage modulus.					
36585891	10	77	dep	grades	1605:1610	arg1	IV					1612:1613	IV	1612:1613	IV	1612:1613	In contrast, grades IV and V correlate with mineralization toward the storage modulus.					
36585891	9	78	from	similarities	1517:1528	arg1	changes					1537:1543	the changes	1533:1543	the changes of Amide I and III	1533:1562	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36585891	7	79	theme	mechanical	1194:1203	arg1	characteristics					1205:1219	mechanical characteristics	1194:1219	mechanical characteristics	1194:1219	Assessment of mechanical characteristics reveals that the increasing disc degeneration makes the NP lose its elasticity, becoming more viscous.					
36585891	0	80	theme	disc	43:46	arg1	stage					32:36	the degenerative stage	15:36	the degenerative stage of a disc	15:46	Correlation of the degenerative stage of a disc with magnetic resonance imaging, chemical content, and biomechanical properties of the nucleus pulposus.					
36585891	1	81	theme	resulting	275:283	arg1	properties					298:307	the resulting viscoelastic properties	271:307	the resulting viscoelastic properties	271:307	Intervertebral disc degeneration (IDD) is closely related to changes in the intervertebral disc (IVD) composition and the resulting viscoelastic properties.					
36585891	11	82	theme	modulus	1758:1764	arg1	changes					1735:1741	the changes	1731:1741	the changes of the storage modulus in all grades of IDD	1731:1785	Reduction of proteoglycan has the highest impact on the changes of the storage modulus in all grades of IDD.					
36585891	5	83	theme	degenerative	957:968	arg1	scoliosis					970:978	degenerative scoliosis	957:978	degenerative scoliosis	957:978	The characterization was, in turn, correlated with the degenerative severity of IVD as assessed using magnetic resonance imaging (MRI) of different patients with spinal stenosis, degenerative spondylolisthesis, and degenerative scoliosis.					
36585891	12	84	from	degrees	1858:1864	arg1	micromechanics					1832:1845	IVD micromechanics	1828:1845	IVD micromechanics at various degrees of degeneration	1828:1880	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	6	85	from	ratio	1039:1043	arg1	collagen					1048:1055	collagen	1048:1055	collagen	1048:1055	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	6	86	from	NP	1176:1177	arg1	level					1144:1148	the severity level	1131:1148	the severity level of the disc damage in the NP	1131:1177	It is shown that there is an increase in the crosslinking ratio in collagen, a reduction in proteoglycan, and a build-up of minerals upon the rise in the severity level of the disc damage in the NP.					
36585891	12	87	theme	critical	1940:1947	arg1	insight					1949:1955	critical insight	1940:1955	critical insight into clinical diagnostics, treatment, and tissue engineering	1940:2016	Connecting compositional alterations to IVD micromechanics at various degrees of degeneration expands our understanding of tissue behavior and provides critical insight into clinical diagnostics, treatment, and tissue engineering.					
36585891	9	88	theme	Amide	1548:1552	arg1	I					1554:1554	Amide I	1548:1554	Amide I	1548:1554	The correlation of the individual discs shows that grades III and IV have similarities in the changes of Amide I and III toward the storage modulus.					
36822151	0	0	theme	flame-retardant	78:92	arg1	electrolyte					106:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	5	1	theme	composite	873:881	arg1	hydrogels					883:891	composite hydrogels	873:891	composite hydrogels	873:891	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	8	2	from	potential	1375:1383	arg1	SSC					1396:1398	SSC	1396:1398	SSC	1396:1398	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	1	3	theme	flexible	180:187	arg1	SSCs					218:221	SSCs	218:221	SSCs	218:221	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	1	3	theme	flexible	180:187	arg1	supercapacitors					201:215	flexible solid-state supercapacitors	180:215	flexible solid-state supercapacitors (SSCs)	180:222	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	8	4	theme	polymer	1409:1415	arg1	electrolyte					1417:1427	a gel polymer electrolyte	1403:1427	a gel polymer electrolyte	1403:1427	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	8	4	theme	polymer	1409:1415	arg1	potential					1375:1383	potential	1375:1383	potential for use in SSC	1375:1398	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	6	5	theme	up	1030:1031	arg1	toughness					1017:1025	a high mechanical toughness	999:1025	a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening	999:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	1	6	theme	solid-state	189:199	arg1	SSCs					218:221	SSCs	218:221	SSCs	218:221	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	1	6	theme	solid-state	189:199	arg1	supercapacitors					201:215	flexible solid-state supercapacitors	180:215	flexible solid-state supercapacitors (SSCs)	180:222	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	4	7	theme	novel	637:641	arg1	approach					643:650	a novel approach	635:650	a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands	635:757	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	0	8	theme	polymer	98:104	arg1	electrolyte					106:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	1	9	theme	stable	299:304	arg1	performance					322:332	stable electrochemical performance	299:332	stable electrochemical performance	299:332	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	0	10	theme	gel	94:96	arg1	electrolyte					106:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	2	11	from	retardancy	390:399	arg1	SSCs					409:412	such SSCs	404:412	such SSCs	404:412	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	2	12	theme	such	404:407	arg1	SSCs					409:412	such SSCs	404:412	such SSCs	404:412	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	1	13	theme	electrochemical	306:320	arg1	performance					322:332	stable electrochemical performance	299:332	stable electrochemical performance	299:332	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	6	14	theme	mechanical	1006:1015	arg1	toughness					1017:1025	a high mechanical toughness	999:1025	a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening	999:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	7	15	theme	excellent	1205:1213	arg1	performance					1231:1241	excellent electrochemical performance	1205:1241	excellent electrochemical performance	1205:1241	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	3	16	theme	polymer-based	579:591	arg1	electrolytes					602:613	natural polymer-based hydrogel electrolytes	571:613	natural polymer-based hydrogel electrolytes	571:613	Furthermore, there is a need for sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes.					
36822151	8	17	theme	proposed	1348:1355	arg1	hydrogel					1357:1364	The proposed hydrogel	1344:1364	The proposed hydrogel	1344:1364	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	6	18	theme	high	1001:1004	arg1	toughness					1017:1025	a high mechanical toughness	999:1025	a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening	999:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	7	19	theme	electrochemical	1215:1229	arg1	performance					1231:1241	excellent electrochemical performance	1205:1241	excellent electrochemical performance	1205:1241	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	3	20	theme	hydrogel	593:600	arg1	electrolytes					602:613	natural polymer-based hydrogel electrolytes	571:613	natural polymer-based hydrogel electrolytes	571:613	Furthermore, there is a need for sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes.					
36822151	4	21	theme	chitosan-reinforced	669:687	arg1	hydrogel					728:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	9	22	theme	supercapacitors	1560:1574	arg1	characteristics					1532:1546	the mechanical, thermal, and electrochemical characteristics	1487:1546	the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules	1487:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	0	23	theme	gelatin	20:26	arg1	hydrogel					38:45	Chitosan-reinforced gelatin composite hydrogel	0:45	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.	0:146	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	9	24	theme	novel	1456:1460	arg1	strategy					1462:1469	a novel strategy	1454:1469	a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules	1454:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	6	25	theme	precipitated	898:909	arg1	chitosan					911:918	The precipitated chitosan	894:918	The precipitated chitosan	894:918	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	7	26	theme	room	1296:1299	arg1	26 °C					1314:1318	26 °C	1314:1318	26 °C	1314:1318	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	7	26	theme	room	1296:1299	arg1	temperature					1301:1311	room temperature	1296:1311	room temperature (26 °C)	1296:1319	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	0	27	theme	Chitosan-reinforced	0:18	arg1	hydrogel					38:45	Chitosan-reinforced gelatin composite hydrogel	0:45	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.	0:146	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	6	28	theme	anti-freezing	1079:1091	arg1	properties					1093:1102	anti-freezing properties	1079:1102	anti-freezing properties (below -30 °C)	1079:1117	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	2	29	theme	subzero	417:423	arg1	temperatures					425:436	subzero temperatures	417:436	subzero temperatures to increase their practical utility	417:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	5	30	theme	hydrogels	801:809	arg1	Immersion					760:768	Immersion	760:768	Immersion of chitosan-containing gelatin hydrogels in salt solutions	760:827	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	9	31	theme	flexible	1551:1558	arg1	supercapacitors					1560:1574	flexible supercapacitors	1551:1574	flexible supercapacitors using biological macromolecules	1551:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	4	32	theme	gelatin	720:726	arg1	hydrogel					728:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	0	33	theme	composite	28:36	arg1	hydrogel					38:45	Chitosan-reinforced gelatin composite hydrogel	0:45	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.	0:146	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	6	34	theme	26 kJ/m2	1069:1076	arg1	properties					1093:1102	anti-freezing properties	1079:1102	anti-freezing properties (below -30 °C)	1079:1117	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	6	34	theme	26 kJ/m2	1069:1076	arg1	energy					1059:1064	a fracture energy	1048:1064	a fracture energy of 26 kJ/m2	1048:1076	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	6	34	theme	26 kJ/m2	1069:1076	arg1	retardancy					1140:1149	excellent flame retardancy	1124:1149	excellent flame retardancy without softening	1124:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	6	34	theme	26 kJ/m2	1069:1076	arg1	3.81 MJ/m3					1036:1045	3.81 MJ/m3	1036:1045	3.81 MJ/m3	1036:1045	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	0	35	theme	flexible	122:129	arg1	supercapacitors					131:145	flexible supercapacitors	122:145	flexible supercapacitors	122:145	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	3	36	theme	bio-friendly	544:555	arg1	SSCs					557:560	sustainable and bio-friendly SSCs	528:560	sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes	528:613	Furthermore, there is a need for sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes.					
36822151	4	37	theme	conductive	709:718	arg1	hydrogel					728:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	1	38	theme	wide	341:344	arg1	range					358:362	a wide temperature range	339:362	a wide temperature range	339:362	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	5	39	theme	salt	814:817	arg1	solutions					819:827	salt solutions	814:827	salt solutions	814:827	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	2	40	theme	practical	456:464	arg1	utility					466:472	their practical utility	450:472	their practical utility	450:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	9	41	theme	biological	1582:1591	arg1	macromolecules					1593:1606	biological macromolecules	1582:1606	biological macromolecules	1582:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	1	42	theme	significant	238:248	arg1	attention					250:258	significant attention	238:258	significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range	238:362	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	6	43	theme	excellent	1124:1132	arg1	retardancy					1140:1149	excellent flame retardancy	1124:1149	excellent flame retardancy without softening	1124:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	1	44	theme	temperature	346:356	arg1	range					358:362	a wide temperature range	339:362	a wide temperature range	339:362	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	9	45	theme	electrochemical	1516:1530	arg1	characteristics					1532:1546	the mechanical, thermal, and electrochemical characteristics	1487:1546	the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules	1487:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	5	46	theme	chitosan	836:843	arg1	precipitation					845:857	chitosan precipitation	836:857	chitosan precipitation	836:857	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	5	47	from	Immersion	760:768	arg1	solutions					819:827	salt solutions	814:827	salt solutions	814:827	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	2	48	from	temperatures	425:436	arg1	retardancy					390:399	achieving flame retardancy	374:399	achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility	374:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	6	49	theme	flame	1134:1138	arg1	retardancy					1140:1149	excellent flame retardancy	1124:1149	excellent flame retardancy without softening	1124:1167	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	7	50	theme	ionic	1252:1256	arg1	conductivity					1258:1269	an ionic conductivity	1249:1269	an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C	1249:1341	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	6	51	theme	fracture	1050:1057	arg1	energy					1059:1064	a fracture energy	1048:1064	a fracture energy of 26 kJ/m2	1048:1076	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	6	52	theme	network	977:983	arg1	reinforcement					939:951	the reinforcement	935:951	the reinforcement of the gelatin hydrogel network	935:983	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	0	53	theme	tough	52:56	arg1	electrolyte					106:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	6	54	theme	hydrogel	968:975	arg1	network					977:983	the gelatin hydrogel network	956:983	the gelatin hydrogel network	956:983	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	2	55	theme	flame	384:388	arg1	retardancy					390:399	achieving flame retardancy	374:399	achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility	374:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	5	56	theme	chitosan-containing	773:791	arg1	hydrogels					801:809	chitosan-containing gelatin hydrogels	773:809	chitosan-containing gelatin hydrogels	773:809	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	6	57	theme	gelatin	960:966	arg1	network					977:983	the gelatin hydrogel network	956:983	the gelatin hydrogel network	956:983	The precipitated chitosan contributes to the reinforcement of the gelatin hydrogel network, resulting in a high mechanical toughness of up to 3.81 MJ/m3, a fracture energy of 26 kJ/m2, anti-freezing properties (below -30 °C), and excellent flame retardancy without softening.					
36822151	2	58	dep	temperatures	425:436	arg1	increase					441:448	increase	441:448	to increase their practical utility	438:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	2	59	theme	achieving	374:382	arg1	retardancy					390:399	achieving flame retardancy	374:399	achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility	374:472	However, achieving flame retardancy in such SSCs at subzero temperatures to increase their practical utility remains challenging.					
36822151	9	60	theme	mechanical	1491:1500	arg1	characteristics					1532:1546	the mechanical, thermal, and electrochemical characteristics	1487:1546	the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules	1487:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	1	61	theme	due	260:262	arg1	attention					250:258	significant attention	238:258	significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range	238:362	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	5	62	theme	gelatin	793:799	arg1	hydrogels					801:809	chitosan-containing gelatin hydrogels	773:809	chitosan-containing gelatin hydrogels	773:809	Immersion of chitosan-containing gelatin hydrogels in salt solutions caused chitosan precipitation, resulting in composite hydrogels.					
36822151	7	63	from	-30 °C	1336:1341	arg1	39 mS/cm					1324:1331	39 mS/cm	1324:1331	39 mS/cm at -30 °C	1324:1341	Furthermore, the hydrogel exhibits excellent electrochemical performance, with an ionic conductivity ranging from 72 mS/cm at room temperature (26 °C) to 39 mS/cm at -30 °C.					
36822151	9	64	theme	thermal	1503:1509	arg1	characteristics					1532:1546	the mechanical, thermal, and electrochemical characteristics	1487:1546	the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules	1487:1606	This study demonstrates a novel strategy for controlling the mechanical, thermal, and electrochemical characteristics of flexible supercapacitors using biological macromolecules.					
36822151	1	65	theme	Hydrogel-based	148:161	arg1	electrolytes					163:174	Hydrogel-based electrolytes	148:174	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs)	148:222	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
36822151	8	66	theme	gel	1405:1407	arg1	electrolyte					1417:1427	a gel polymer electrolyte	1403:1427	a gel polymer electrolyte	1403:1427	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	8	66	theme	gel	1405:1407	arg1	potential					1375:1383	potential	1375:1383	potential for use in SSC	1375:1398	The proposed hydrogel exhibits potential for use in SSC as a gel polymer electrolyte.					
36822151	3	67	theme	sustainable	528:538	arg1	SSCs					557:560	sustainable and bio-friendly SSCs	528:560	sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes	528:613	Furthermore, there is a need for sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes.					
36822151	4	68	theme	ionic	703:707	arg1	hydrogel					728:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	0	69	theme	anti-freezing	59:71	arg1	electrolyte					106:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	a tough, anti-freezing, and flame-retardant gel polymer electrolyte	50:116	Chitosan-reinforced gelatin composite hydrogel as a tough, anti-freezing, and flame-retardant gel polymer electrolyte for flexible supercapacitors.					
36822151	4	70	theme	anti-freezing	689:701	arg1	hydrogel					728:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel	667:735	This study reports a novel approach for developing a chitosan-reinforced anti-freezing ionic conductive gelatin hydrogel to meet these demands.					
36822151	3	71	theme	natural	571:577	arg1	electrolytes					602:613	natural polymer-based hydrogel electrolytes	571:613	natural polymer-based hydrogel electrolytes	571:613	Furthermore, there is a need for sustainable and bio-friendly SSCs that use natural polymer-based hydrogel electrolytes.					
36822151	1	72	theme	mechanical	273:282	arg1	robustness					284:293	their mechanical robustness	267:293	their mechanical robustness	267:293	Hydrogel-based electrolytes for flexible solid-state supercapacitors (SSCs) have received significant attention due to their mechanical robustness and stable electrochemical performance over a wide temperature range.					
35563609	1	0	theme	bioresources	149:160	arg1	use					142:144	the efficient use	128:144	the efficient use of bioresources and bioproducts	128:176	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	2	1	theme	Raman	427:431	arg1	spectra					433:439	Raman spectra	427:439	Raman spectra	427:439	The structure and morphology were fully characterized by XRD, SEM, FTIR, XPS and Raman spectra.					
35563609	6	2	theme	hydrogen	796:803	arg1	bonding					805:811	hydrogen bonding	796:811	hydrogen bonding	796:811	The interactions among ZnO, PPL and cellulose have been attributed to hydrogen bonding, which plays an important role in guiding the formation of composites.					
35563609	6	3	theme	composites	872:881	arg1	formation					859:867	the formation	855:867	the formation of composites	855:881	The interactions among ZnO, PPL and cellulose have been attributed to hydrogen bonding, which plays an important role in guiding the formation of composites.					
35563609	0	4	theme	Antibacterial	89:101	arg1	Activity					103:110	Its Enhanced Antibacterial Activity	76:110	Its Enhanced Antibacterial Activity	76:110	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	8	5	contain	has	1083:1085	arg2	activity					1110:1117	superior antibacterial activity	1087:1117	superior antibacterial activity	1087:1117	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	8	5	contain	has	1083:1085	arg1	PPL/Cel					1075:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	0	6	theme	Enhanced	80:87	arg1	Activity					103:110	Its Enhanced Antibacterial Activity	76:110	Its Enhanced Antibacterial Activity	76:110	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	1	7	theme	active	321:326	arg1	material					336:343	an active package material	318:343	an active package material	318:343	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	10	8	theme	@	1264:1264	arg1	PPL/Cel					1265:1271	ZnO@PPL/Cel	1261:1271	ZnO@PPL/Cel	1261:1271	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	7	9	dep	coli	947:950	arg1	coli					956:959	E. coli	953:959	E. coli	953:959	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method.					
35563609	1	10	theme	package	328:334	arg1	material					336:343	an active package material	318:343	an active package material	318:343	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	10	11	theme	ZnO	1261:1263	arg1	PPL/Cel					1265:1271	ZnO@PPL/Cel	1261:1271	ZnO@PPL/Cel	1261:1271	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	8	12	theme	@	1074:1074	arg1	PPL/Cel					1075:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	1	13	theme	bioproducts	166:176	arg1	use					142:144	the efficient use	128:144	the efficient use of bioresources and bioproducts	128:176	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	8	14	theme	superior	1087:1094	arg1	activity					1110:1117	superior antibacterial activity	1087:1117	superior antibacterial activity	1087:1117	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	8	15	theme	composite	1061:1069	arg1	PPL/Cel					1075:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	7	16	dep	aureus	995:1000	arg1	aureus					1006:1011	S. aureus	1003:1011	S. aureus	1003:1011	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method.					
35563609	5	17	theme	50	708:709	arg1	nm					711:712	nm	711:712	nm	711:712	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	10	18	theme	food	1326:1329	arg1	packaging					1331:1339	active food packaging	1319:1339	active food packaging	1319:1339	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	10	18	theme	food	1326:1329	arg1	it					1299:1300	it	1299:1300	it	1299:1300	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	1	19	with	PPL/Cel	267:273	arg1	cellulose					280:288	cellulose	280:288	cellulose	280:288	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	1	20	theme	plant	179:183	arg1	PPL					197:199	PPL	197:199	PPL	197:199	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	1	20	theme	plant	179:183	arg1	polyphenol					185:194	plant polyphenol	179:194	plant polyphenol (PPL)	179:200	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	5	21	theme	nm	711:712	arg1	slices					718:723	50 nm ZnO slices	708:723	50 nm ZnO slices	708:723	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	10	22	theme	active	1319:1324	arg1	packaging					1331:1339	active food packaging	1319:1339	active food packaging	1319:1339	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	10	22	theme	active	1319:1324	arg1	it					1299:1300	it	1299:1300	it	1299:1300	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	0	23	theme	@	18:18	arg1	Polyphenols/Cellulose					25:45	ZnO@Plant Polyphenols/Cellulose	15:45	ZnO@Plant Polyphenols/Cellulose	15:45	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	1	24	theme	ZnO	263:265	arg1	PPL/Cel					267:273	ZnO@PPL/Cel	263:273	ZnO@PPL/Cel with cellulose to examine its potential as an active package material	263:343	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	10	25	theme	low	1201:1203	arg1	cost					1205:1208	The low cost	1197:1208	The low cost	1197:1208	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	0	26	theme	ZnO	15:17	arg1	Polyphenols/Cellulose					25:45	ZnO@Plant Polyphenols/Cellulose	15:45	ZnO@Plant Polyphenols/Cellulose	15:45	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	1	27	theme	@	266:266	arg1	PPL/Cel					267:273	ZnO@PPL/Cel	263:273	ZnO@PPL/Cel with cellulose to examine its potential as an active package material	263:343	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	5	28	from	morphology	653:662	arg1	ZnO					667:669	ZnO	667:669	ZnO	667:669	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	0	29	theme	Polyphenols/Cellulose	25:45	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.	0:111	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	5	30	with	Coating	612:618	arg1	PPL					625:627	PPL	625:627	PPL	625:627	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	0	31	theme	Plant	19:23	arg1	Polyphenols/Cellulose					25:45	ZnO@Plant Polyphenols/Cellulose	15:45	ZnO@Plant Polyphenols/Cellulose	15:45	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	6	32	theme	important	829:837	arg1	role					839:842	an important role	826:842	an important role	826:842	The interactions among ZnO, PPL and cellulose have been attributed to hydrogen bonding, which plays an important role in guiding the formation of composites.					
35563609	7	33	theme	inhibition	1033:1042	arg1	method					1049:1054	the inhibition zone method	1029:1054	the inhibition zone method	1029:1054	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method.					
35563609	5	34	theme	ZnO	714:716	arg1	slices					718:723	50 nm ZnO slices	708:723	50 nm ZnO slices	708:723	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	0	35	theme	Active	50:55	arg1	Packaging					62:70	Active Food Packaging	50:70	Active Food Packaging	50:70	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	3	36	theme	coating	496:502	arg1	layer					504:508	a coating layer	494:508	a coating layer	494:508	It was found that PPL is able to cover ZnO and form a coating layer.					
35563609	10	37	theme	preparation	1218:1228	arg1	method					1230:1235	simple preparation method	1211:1235	simple preparation method	1211:1235	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	8	38	theme	antibacterial	1096:1108	arg1	activity					1110:1117	superior antibacterial activity	1087:1117	superior antibacterial activity	1087:1117	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	10	39	theme	PPL/Cel	1265:1271	arg1	method					1230:1235	simple preparation method	1211:1235	simple preparation method	1211:1235	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	10	39	theme	PPL/Cel	1265:1271	arg1	performance					1246:1256	good performance	1241:1256	good performance	1241:1256	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	10	39	theme	PPL/Cel	1265:1271	arg1	cost					1205:1208	The low cost	1197:1208	The low cost	1197:1208	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	10	40	theme	simple	1211:1216	arg1	method					1230:1235	simple preparation method	1211:1235	simple preparation method	1211:1235	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	7	41	theme	zone	1044:1047	arg1	method					1049:1054	the inhibition zone method	1029:1054	the inhibition zone method	1029:1054	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method.					
35563609	9	42	theme	antibacterial	1144:1156	arg1	mechanism					1158:1166	The antibacterial mechanism	1140:1166	The antibacterial mechanism	1140:1166	The antibacterial mechanism has also been elaborated on.					
35563609	7	43	theme	antibacterial	888:900	arg1	properties					902:911	The antibacterial properties	884:911	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus)	884:1012	The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method.					
35563609	1	44	theme	efficient	132:140	arg1	use					142:144	the efficient use	128:144	the efficient use of bioresources and bioproducts	128:176	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	4	45	theme	cellulose	594:602	arg1	fibers					604:609	the cellulose fibers	590:609	the cellulose fibers	590:609	In addition, PPL cross-links with cellulose and makes ZnO distribute evenly on the cellulose fibers.					
35563609	1	46	theme	larch	221:225	arg1	bark					227:230	larch bark	221:230	larch bark	221:230	To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material.					
35563609	0	47	theme	Food	57:60	arg1	Packaging					62:70	Active Food Packaging	50:70	Active Food Packaging	50:70	Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity.					
35563609	5	48	theme	slices	718:723	arg1	subunits					696:703	subunits	696:703	subunits of 50 nm ZnO slices	696:723	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
35563609	10	49	theme	good	1241:1244	arg1	performance					1246:1256	good performance	1241:1256	good performance	1241:1256	The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging.					
35563609	8	50	theme	ZnO	1071:1073	arg1	PPL/Cel					1075:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel	1057:1081	Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel.					
35563609	5	51	theme	pinecone-like	639:651	arg1	morphology					653:662	a pinecone-like morphology	637:662	a pinecone-like morphology	637:662	Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices.					
36581021	7	0	theme	human	1436:1440	arg1	health-care					1442:1452	human health-care	1436:1452	human health-care	1436:1452	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	4	1	theme	amino	692:696	arg1	groups					698:703	amino groups	692:703	amino groups	692:703	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	5	2	theme	amino	1097:1101	arg1	groups					1103:1108	the amino groups	1093:1108	the amino groups	1093:1108	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	2	3	theme	output	368:373	arg1	performance					375:385	the output performance	364:385	the output performance of CPTENGs	364:396	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	1	4	theme	miniaturized	256:267	arg1	products					280:287	wearable, green and miniaturized electronic products	236:287	wearable, green and miniaturized electronic products	236:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	2	5	theme	paper	491:495	arg1	property					469:476	the triboelectric property	451:476	the triboelectric property of cellulose paper	451:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	4	6	theme	output	869:874	arg1	performance					876:886	outstanding output performance	857:886	outstanding output performance	857:886	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	5	7	theme	current	902:908	arg1	values					933:938	The voltage, current and power density peak values	889:938	The voltage, current and power density peak values of PEO/CCP based TENG	889:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	4	8	dep	higher	743:748	arg1	property					773:780	triboelectric positive property	750:780	triboelectric positive property	750:780	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	4	9	with	TENG	847:850	arg1	performance					876:886	outstanding output performance	857:886	outstanding output performance	857:886	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	1	10	theme	electronic	269:278	arg1	products					280:287	wearable, green and miniaturized electronic products	236:287	wearable, green and miniaturized electronic products	236:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	5	11	theme	groups	1003:1008	arg1	content					1010:1016	amino groups content	997:1016	amino groups content	997:1016	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	4	12	theme	PEO/CCP	833:839	arg1	TENG					847:850	PEO/CCP based TENG	833:850	PEO/CCP based TENG with outstanding output performance	833:886	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	2	13	theme	fibers	316:321	arg1	Modification					290:301	Modification	290:301	Modification of cellulose fibers or paper	290:330	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	13	theme	fibers	316:321	arg1	method					346:351	a feasible method	335:351	a feasible method to improve the output performance of CPTENGs	335:396	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	5	14	theme	TENG	957:960	arg1	values					933:938	The voltage, current and power density peak values	889:938	The voltage, current and power density peak values of PEO/CCP based TENG	889:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	1	15	theme	products	280:287	arg1	development					221:231	the development	217:231	the development of wearable, green and miniaturized electronic products	217:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	6	16	theme	power	1136:1140	arg1	222.1 V					1185:1191	222.1 V	1185:1191	222.1 V	1185:1191	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	6	16	theme	power	1136:1140	arg1	density					1142:1148	The voltage, current and power density	1111:1148	density	1142:1148	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	7	17	theme	promising	1395:1403	arg1	muscles					1345:1351	eye muscles	1341:1351	eye muscles	1341:1351	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	17	theme	promising	1395:1403	arg1	potentials					1405:1414	promising potentials	1395:1414	promising potentials for applications in human health-care	1395:1452	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	3	18	theme	simple	543:548	arg1	method					550:555	a simple method	541:555	a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers	541:673	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	2	19	theme	cellulose	306:314	arg1	fibers					316:321	cellulose fibers	306:321	cellulose fibers	306:321	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	6	20	theme	voltage	1115:1121	arg1	222.1 V					1185:1191	222.1 V	1185:1191	222.1 V	1185:1191	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	6	20	theme	voltage	1115:1121	arg1	density					1142:1148	The voltage, current and power density	1111:1148	density	1142:1148	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	7	21	theme	heart	1367:1371	arg1	beat					1373:1376	heart beat	1367:1376	heart beat	1367:1376	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	21	theme	heart	1367:1371	arg1	muscles					1345:1351	eye muscles	1341:1351	eye muscles	1341:1351	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	22	theme	wrist	1382:1386	arg1	pulse					1388:1392	wrist pulse	1382:1392	wrist pulse	1382:1392	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	22	theme	wrist	1382:1386	arg1	muscles					1345:1351	eye muscles	1341:1351	eye muscles	1341:1351	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	0	23	from	nanogenerator	50:62	arg1	detection					100:108	human-health detection	87:108	human-health detection	87:108	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	2	24	dep	routes	433:438	arg1	improve					443:449	improve	443:449	to improve the triboelectric property of cellulose paper	440:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	6	25	theme	current	1124:1130	arg1	222.1 V					1185:1191	222.1 V	1185:1191	222.1 V	1185:1191	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	6	25	theme	current	1124:1130	arg1	density					1142:1148	The voltage, current and power density	1111:1148	density	1142:1148	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	4	26	theme	positive	764:771	arg1	property					773:780	triboelectric positive property	750:780	triboelectric positive property	750:780	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	0	27	theme	composite	14:22	arg1	paper					24:28	PEO/cellulose composite paper	0:28	PEO/cellulose composite paper	0:28	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	0	28	theme	human-health	87:98	arg1	detection					100:108	human-health detection	87:108	human-health detection	87:108	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	4	29	theme	outstanding	857:867	arg1	performance					876:886	outstanding output performance	857:886	outstanding output performance	857:886	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	4	30	theme	composite	718:726	arg1	paper					728:732	the composite paper	714:732	the composite paper	714:732	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	0	31	theme	PEO/cellulose	0:12	arg1	paper					24:28	PEO/cellulose composite paper	0:28	PEO/cellulose composite paper	0:28	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	3	32	theme	PEO/cellulose	568:580	arg1	PEO/CCP					599:605	PEO/CCP	599:605	PEO/CCP	599:605	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	3	32	theme	PEO/cellulose	568:580	arg1	paper					592:596	PEO/cellulose composite paper	568:596	PEO/cellulose composite paper (PEO/CCP)	568:606	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	4	33	theme	triboelectric	750:762	arg1	property					773:780	triboelectric positive property	750:780	triboelectric positive property	750:780	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	1	34	theme	due	210:212	arg1	attention					200:208	widely attention	193:208	widely attention due to the development of wearable, green and miniaturized electronic products	193:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	2	35	theme	paper	326:330	arg1	Modification					290:301	Modification	290:301	Modification of cellulose fibers or paper	290:330	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	35	theme	paper	326:330	arg1	method					346:351	a feasible method	335:351	a feasible method to improve the output performance of CPTENGs	335:396	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	36	theme	effective	423:431	arg1	routes					433:438	the simple and effective routes	408:438	the simple and effective routes to improve the triboelectric property of cellulose paper	408:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	5	37	theme	PEO/CCP	943:949	arg1	TENG					957:960	PEO/CCP based TENG	943:960	PEO/CCP based TENG	943:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	6	38	theme	based	1161:1165	arg1	TENG					1167:1170	PEO/CCP based TENG	1153:1170	PEO/CCP based TENG	1153:1170	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	5	39	theme	TENGs	1060:1064	arg1	performance					1041:1051	the performance	1037:1051	the performance of the TENGs	1037:1064	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	1	40	theme	cellulose	121:129	arg1	paper					131:135	cellulose paper	121:135	cellulose paper based triboelectric nanogenerators (CPTENGs)	121:180	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	5	41	theme	linear	972:977	arg1	relationship					979:990	linear relationship	972:990	linear relationship	972:990	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	2	42	theme	cellulose	481:489	arg1	paper					491:495	cellulose paper	481:495	cellulose paper	481:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	43	theme	CPTENGs	390:396	arg1	performance					375:385	the output performance	364:385	the output performance of CPTENGs	364:396	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	44	theme	simple	412:417	arg1	routes					433:438	the simple and effective routes	408:438	the simple and effective routes to improve the triboelectric property of cellulose paper	408:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	0	45	theme	triboelectric	36:48	arg1	nanogenerator					50:62	triboelectric nanogenerator	36:62	triboelectric nanogenerator	36:62	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	7	46	from	applications	1420:1431	arg1	health-care					1442:1452	human health-care	1436:1452	human health-care	1436:1452	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	47	theme	eye	1341:1343	arg1	respiration					1354:1364	respiration	1354:1364	respiration	1354:1364	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	47	theme	eye	1341:1343	arg1	beat					1373:1376	heart beat	1367:1376	heart beat	1367:1376	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	47	theme	eye	1341:1343	arg1	muscles					1345:1351	eye muscles	1341:1351	eye muscles	1341:1351	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	47	theme	eye	1341:1343	arg1	potentials					1405:1414	promising potentials	1395:1414	promising potentials for applications in human health-care	1395:1452	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	47	theme	eye	1341:1343	arg1	pulse					1388:1392	wrist pulse	1382:1392	wrist pulse	1382:1392	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	48	theme	human-health	1246:1257	arg1	device					1269:1274	a human-health detection device	1244:1274	a human-health detection device based on this TENG	1244:1293	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	0	49	from	application	72:82	arg1	detection					100:108	human-health detection	87:108	human-health detection	87:108	PEO/cellulose composite paper based triboelectric nanogenerator and its application in human-health detection.					
36581021	3	50	theme	composite	582:590	arg1	PEO/CCP					599:605	PEO/CCP	599:605	PEO/CCP	599:605	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	3	50	theme	composite	582:590	arg1	paper					592:596	PEO/cellulose composite paper	568:596	PEO/cellulose composite paper (PEO/CCP)	568:606	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	5	51	theme	power	914:918	arg1	density					920:926	power density	914:926	power density	914:926	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	2	52	theme	triboelectric	455:467	arg1	property					469:476	the triboelectric property	451:476	the triboelectric property of cellulose paper	451:495	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	6	53	theme	PEO/CCP	1153:1159	arg1	TENG					1167:1170	PEO/CCP based TENG	1153:1170	PEO/CCP based TENG	1153:1170	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	3	54	theme	cellulose	658:666	arg1	fibers					668:673	cationic cellulose fibers	649:673	cationic cellulose fibers	649:673	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	4	55	theme	based	841:845	arg1	TENG					847:850	PEO/CCP based TENG	833:850	PEO/CCP based TENG with outstanding output performance	833:886	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	5	56	theme	density	920:926	arg1	values					933:938	The voltage, current and power density peak values	889:938	The voltage, current and power density peak values of PEO/CCP based TENG	889:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	6	57	theme	TENG	1167:1170	arg1	222.1 V					1185:1191	222.1 V	1185:1191	222.1 V	1185:1191	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	6	57	theme	TENG	1167:1170	arg1	density					1142:1148	The voltage, current and power density	1111:1148	density	1142:1148	The voltage, current and power density of PEO/CCP based TENG can be up to 222.1 V, 4.3 μA, and 217.3 mW•m-2, respectively.					
36581021	5	58	theme	amino	997:1001	arg1	groups					1003:1008	amino groups	997:1008	amino groups content	997:1016	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	4	59	theme	triboelectric	786:798	arg1	density					807:813	triboelectric charge density	786:813	triboelectric charge density	786:813	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
36581021	1	60	theme	triboelectric	143:155	arg1	CPTENGs					173:179	CPTENGs	173:179	CPTENGs	173:179	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	1	60	theme	triboelectric	143:155	arg1	nanogenerators					157:170	triboelectric nanogenerators	143:170	triboelectric nanogenerators (CPTENGs)	143:180	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	5	61	theme	based	951:955	arg1	TENG					957:960	PEO/CCP based TENG	943:960	PEO/CCP based TENG	943:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	1	62	theme	wearable	236:243	arg1	products					280:287	wearable, green and miniaturized electronic products	236:287	wearable, green and miniaturized electronic products	236:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	3	63	theme	polyethylene	619:630	arg1	PEO					639:641	PEO	639:641	PEO	639:641	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	3	63	theme	polyethylene	619:630	arg1	oxide					632:636	polyethylene oxide	619:636	polyethylene oxide (PEO)	619:642	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	2	64	theme	feasible	337:344	arg1	Modification					290:301	Modification	290:301	Modification of cellulose fibers or paper	290:330	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	2	64	theme	feasible	337:344	arg1	method					346:351	a feasible method	335:351	a feasible method to improve the output performance of CPTENGs	335:396	Modification of cellulose fibers or paper is a feasible method to improve the output performance of CPTENGs, however, the simple and effective routes to improve the triboelectric property of cellulose paper still remain a challenge.					
36581021	5	65	theme	peak	928:931	arg1	values					933:938	The voltage, current and power density peak values	889:938	The voltage, current and power density peak values of PEO/CCP based TENG	889:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	3	66	theme	cationic	649:656	arg1	fibers					668:673	cationic cellulose fibers	649:673	cationic cellulose fibers	649:673	Herein, we report a simple method to prepare PEO/cellulose composite paper (PEO/CCP) via mixing polyethylene oxide (PEO) with cationic cellulose fibers.					
36581021	7	67	theme	detection	1259:1267	arg1	device					1269:1274	a human-health detection device	1244:1274	a human-health detection device based on this TENG	1244:1293	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	5	68	theme	voltage	893:899	arg1	values					933:938	The voltage, current and power density peak values	889:938	The voltage, current and power density peak values of PEO/CCP based TENG	889:960	The voltage, current and power density peak values of PEO/CCP based TENG exhibited linear relationship with amino groups content; in this instance, the performance of the TENGs can be readily adjusted by the amino groups.					
36581021	1	69	theme	green	246:250	arg1	products					280:287	wearable, green and miniaturized electronic products	236:287	wearable, green and miniaturized electronic products	236:287	Recently, cellulose paper based triboelectric nanogenerators (CPTENGs) has gained widely attention due to the development of wearable, green and miniaturized electronic products.					
36581021	7	70	theme	physiological	1311:1323	arg1	muscles					1345:1351	eye muscles	1341:1351	eye muscles	1341:1351	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	7	70	theme	physiological	1311:1323	arg1	signals					1325:1331	the physiological signals	1307:1331	the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care	1307:1452	Moreover, a human-health detection device based on this TENG can monitor the physiological signals such as eye muscles, respiration, heart beat and wrist pulse, promising potentials for applications in human health-care.					
36581021	4	71	theme	charge	800:805	arg1	density					807:813	triboelectric charge density	786:813	triboelectric charge density	786:813	Benefiting from amino groups and PEO, the composite paper exhibits higher triboelectric positive property and triboelectric charge density, thereby endowing PEO/CCP based TENG with outstanding output performance.					
37249568	10	0	theme	anticoagulant	1548:1560	arg1	treatment					1562:1570	the anticoagulant treatment	1544:1570	the anticoagulant treatment for medical devices	1544:1590	The composite coating constructed in this work show great potential in the anticoagulant treatment for medical devices.					
37249568	4	1	theme	PDAM/lysine	707:717	arg1	coating					719:725	the PDAM/lysine coating	703:725	the PDAM/lysine coating rich in amine groups	703:746	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	3	2	theme	used	526:529	arg1	tubes					566:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	6	3	theme	anticoagulant	1009:1021	arg1	properties					1023:1032	anticoagulant properties	1009:1032	anticoagulant properties of the composite coating	1009:1057	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	5	4	theme	PDAM/lysine	904:914	arg1	coating					916:922	the PDAM/lysine coating	900:922	the PDAM/lysine coating to obtain composite coating	900:950	Then, the modified heparin was covalently immobilized on the PDAM/lysine coating to obtain composite coating.					
37249568	3	5	theme	medical	531:537	arg1	tubes					566:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	10	6	theme	medical	1576:1582	arg1	devices					1584:1590	medical devices	1576:1590	medical devices	1576:1590	The composite coating constructed in this work show great potential in the anticoagulant treatment for medical devices.					
37249568	4	7	theme	dopamine	787:794	arg1	solution					775:782	a mixed solution	767:782	a mixed solution of dopamine and lysine	767:805	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	4	8	theme	mixed	769:773	arg1	solution					775:782	a mixed solution	767:782	a mixed solution of dopamine and lysine	767:805	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	6	9	theme	heparin	997:1003	arg1	density					972:978	graft density	966:978	graft density	966:978	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	6	9	theme	heparin	997:1003	arg1	properties					1023:1032	anticoagulant properties	1009:1032	anticoagulant properties of the composite coating	1009:1057	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	6	9	theme	heparin	997:1003	arg1	stability					984:992	stability	984:992	stability	984:992	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	2	10	theme	bleeding	320:327	arg1	hypersensitivity					330:345	hypersensitivity	330:345	hypersensitivity	330:345	However, intravenous anticoagulants such as heparin may induce bleeding, hypersensitivity, and other adverse reactions.					
37249568	9	11	theme	in	1440:1441	arg1	test					1467:1470	the in vitro blood circulation test	1436:1470	the in vitro blood circulation test	1436:1470	Particularly, the anticoagulant coating performed well in the in vitro blood circulation test.					
37249568	7	12	theme	partial	1213:1219	arg1	time					1236:1239	the activated partial thromboplastin time	1199:1239	the activated partial thromboplastin time (APTT)	1199:1246	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	12	theme	partial	1213:1219	arg1	APTT					1242:1245	APTT	1242:1245	APTT	1242:1245	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	4	13	theme	rich	727:730	arg1	coating					719:725	the PDAM/lysine coating	703:725	the PDAM/lysine coating rich in amine groups	703:746	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	3	14	theme	vinyl	544:548	arg1	poly					539:542	poly	539:542	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	3	14	theme	vinyl	544:548	arg1	chloride					550:557	vinyl chloride	544:557	vinyl chloride	544:557	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	7	15	dep	adhesion	1136:1143	arg1	the					1132:1134	the	1132:1134	the	1132:1134	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	16	theme	thromboplastin	1221:1234	arg1	time					1236:1239	the activated partial thromboplastin time	1199:1239	the activated partial thromboplastin time (APTT)	1199:1246	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	16	theme	thromboplastin	1221:1234	arg1	APTT					1242:1245	APTT	1242:1245	APTT	1242:1245	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	6	17	dep	density	972:978	arg1	the					962:964	the	962:964	the	962:964	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	7	18	theme	platelets	1163:1171	arg1	activation					1149:1158	activation	1149:1158	activation	1149:1158	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	18	theme	platelets	1163:1171	arg1	adhesion					1136:1143	adhesion	1136:1143	adhesion	1136:1143	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	9	19	theme	anticoagulant	1396:1408	arg1	coating					1410:1416	the anticoagulant coating	1392:1416	the anticoagulant coating	1392:1416	Particularly, the anticoagulant coating performed well in the in vitro blood circulation test.					
37249568	9	20	theme	blood	1449:1453	arg1	test					1467:1470	the in vitro blood circulation test	1436:1470	the in vitro blood circulation test	1436:1470	Particularly, the anticoagulant coating performed well in the in vitro blood circulation test.					
37249568	2	21	theme	other	352:356	arg1	reactions					366:374	other adverse reactions	352:374	other adverse reactions	352:374	However, intravenous anticoagulants such as heparin may induce bleeding, hypersensitivity, and other adverse reactions.					
37249568	1	22	theme	life	214:217	arg1	safety					219:224	the life safety	210:224	the life safety of the patients	210:240	The thrombosis of the extracorporeal circuits leads to serious complications, which affect the life safety of the patients significantly.					
37249568	7	23	theme	activated	1203:1211	arg1	time					1236:1239	the activated partial thromboplastin time	1199:1239	the activated partial thromboplastin time (APTT)	1199:1246	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	23	theme	activated	1203:1211	arg1	APTT					1242:1245	APTT	1242:1245	APTT	1242:1245	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	7	24	theme	composite	1100:1108	arg1	coating					1110:1116	the composite coating	1096:1116	the composite coating	1096:1116	The results showed that the composite coating could inhibit the adhesion and activation of platelets significantly and prolong the activated partial thromboplastin time (APTT) remarkably for over 25 s.					
37249568	5	25	dep	coating	916:922	arg1	obtain					927:932	obtain	927:932	to obtain composite coating	924:950	Then, the modified heparin was covalently immobilized on the PDAM/lysine coating to obtain composite coating.					
37249568	0	26	theme	Mussel-Inspired	20:34	arg1	Coating					66:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	4	27	from	groups	741:746	arg1	rich					727:730	rich	727:730	rich	727:730	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	4	28	theme	co-deposition	819:831	arg1	reaction					833:840	the co-deposition reaction	815:840	the co-deposition reaction	815:840	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	8	29	theme	composite	1278:1286	arg1	coating					1288:1294	The composite coating	1274:1294	The composite coating	1274:1294	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	3	30	theme	composite	412:420	arg1	coating					422:428	the mussel-inspired composite coating	392:428	the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin	392:492	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	8	31	theme	hemolysis	1342:1350	arg1	%					1375:1375	less than 0.5%	1362:1375	less than 0.5%	1362:1375	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	8	31	theme	hemolysis	1342:1350	arg1	ratio					1352:1356	the hemolysis ratio	1338:1356	the hemolysis ratio	1338:1356	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	1	32	theme	serious	174:180	arg1	complications					182:194	serious complications	174:194	serious complications	174:194	The thrombosis of the extracorporeal circuits leads to serious complications, which affect the life safety of the patients significantly.					
37249568	0	33	theme	Composite	56:64	arg1	Coating					66:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	6	34	theme	graft	966:970	arg1	density					972:978	graft density	966:978	graft density	966:978	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	2	35	theme	intravenous	266:276	arg1	anticoagulants					278:291	intravenous anticoagulants	266:291	intravenous anticoagulants such as heparin	266:307	However, intravenous anticoagulants such as heparin may induce bleeding, hypersensitivity, and other adverse reactions.					
37249568	2	35	theme	intravenous	266:276	arg1	heparin					301:307	heparin	301:307	heparin	301:307	However, intravenous anticoagulants such as heparin may induce bleeding, hypersensitivity, and other adverse reactions.					
37249568	1	36	theme	patients	233:240	arg1	safety					219:224	the life safety	210:224	the life safety of the patients	210:240	The thrombosis of the extracorporeal circuits leads to serious complications, which affect the life safety of the patients significantly.					
37249568	0	37	theme	PDAM/Lysine/Heparin	36:54	arg1	Coating					66:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	16:72	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	3	38	theme	mussel-inspired	396:410	arg1	coating					422:428	the mussel-inspired composite coating	392:428	the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin	392:492	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	5	39	theme	modified	853:860	arg1	heparin					862:868	the modified heparin	849:868	the modified heparin	849:868	Then, the modified heparin was covalently immobilized on the PDAM/lysine coating to obtain composite coating.					
37249568	3	40	theme	modified	477:484	arg1	heparin					486:492	modified heparin	477:492	modified heparin	477:492	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	8	41	theme	excellent	1305:1313	arg1	hemocompatibility					1315:1331	excellent hemocompatibility	1305:1331	excellent hemocompatibility	1305:1331	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	6	42	theme	coating	1051:1057	arg1	density					972:978	graft density	966:978	graft density	966:978	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	6	42	theme	coating	1051:1057	arg1	properties					1023:1032	anticoagulant properties	1009:1032	anticoagulant properties of the composite coating	1009:1057	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	6	42	theme	coating	1051:1057	arg1	stability					984:992	stability	984:992	stability	984:992	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	10	43	theme	great	1525:1529	arg1	potential					1531:1539	great potential	1525:1539	great potential	1525:1539	The composite coating constructed in this work show great potential in the anticoagulant treatment for medical devices.					
37249568	1	44	theme	extracorporeal	141:154	arg1	circuits					156:163	the extracorporeal circuits	137:163	the extracorporeal circuits	137:163	The thrombosis of the extracorporeal circuits leads to serious complications, which affect the life safety of the patients significantly.					
37249568	0	45	theme	Coating	66:72	arg1	Construction					0:11	Construction	0:11	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating	0:72	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	3	46	theme	strategies	684:693	arg1	construction					651:662	the construction	647:662	the construction of bioinert surface strategies	647:693	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	3	46	theme	strategies	684:693	arg1	immobilization					610:623	the immobilization	606:623	the immobilization of anticoagulants	606:641	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	10	47	theme	composite	1477:1485	arg1	coating					1487:1493	The composite coating	1473:1493	The composite coating constructed in this work	1473:1518	The composite coating constructed in this work show great potential in the anticoagulant treatment for medical devices.					
37249568	1	48	theme	circuits	156:163	arg1	thrombosis					123:132	The thrombosis	119:132	The thrombosis of the extracorporeal circuits	119:163	The thrombosis of the extracorporeal circuits leads to serious complications, which affect the life safety of the patients significantly.					
37249568	8	49	contain	had	1301:1303	arg1	coating					1288:1294	The composite coating	1274:1294	The composite coating	1274:1294	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	8	49	contain	had	1301:1303	arg2	hemocompatibility					1315:1331	excellent hemocompatibility	1305:1331	excellent hemocompatibility	1305:1331	The composite coating also had excellent hemocompatibility, and the hemolysis ratio was less than 0.5%.					
37249568	9	50	dep	in	1440:1441	arg1	vitro					1443:1447	vitro	1443:1447	vitro	1443:1447	Particularly, the anticoagulant coating performed well in the in vitro blood circulation test.					
37249568	4	51	theme	amine	735:739	arg1	groups					741:746	amine groups	735:746	amine groups	735:746	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	6	52	theme	composite	1041:1049	arg1	coating					1051:1057	the composite coating	1037:1057	the composite coating	1037:1057	Finally, the graft density and stability of heparin and anticoagulant properties of the composite coating were tested.					
37249568	3	53	theme	bioinert	667:674	arg1	strategies					684:693	bioinert surface strategies	667:693	bioinert surface strategies	667:693	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	3	54	theme	anticoagulants	628:641	arg1	construction					651:662	the construction	647:662	the construction of bioinert surface strategies	647:693	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	3	54	theme	anticoagulants	628:641	arg1	immobilization					610:623	the immobilization	606:623	the immobilization of anticoagulants	606:641	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	2	55	theme	adverse	358:364	arg1	reactions					366:374	other adverse reactions	352:374	other adverse reactions	352:374	However, intravenous anticoagulants such as heparin may induce bleeding, hypersensitivity, and other adverse reactions.					
37249568	4	56	from	rich	727:730	arg1	groups					741:746	amine groups	735:746	amine groups	735:746	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
37249568	5	57	theme	composite	934:942	arg1	coating					944:950	composite coating	934:950	composite coating	934:950	Then, the modified heparin was covalently immobilized on the PDAM/lysine coating to obtain composite coating.					
37249568	0	58	theme	Anticoagulant	93:105	arg1	Strategies					107:116	Multiple Anticoagulant Strategies	84:116	Multiple Anticoagulant Strategies	84:116	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	3	59	theme	surface	676:682	arg1	strategies					684:693	bioinert surface strategies	667:693	bioinert surface strategies	667:693	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	3	60	theme	poly	539:542	arg1	tubes					566:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	the commonly used medical poly(vinyl chloride) (PVC) tubes	513:570	In this study, the mussel-inspired composite coating consisting of polydopamine (PDAM), lysine, and modified heparin was constructed on the commonly used medical poly(vinyl chloride) (PVC) tubes to reduce thrombosis by combining the immobilization of anticoagulants and the construction of bioinert surface strategies.					
37249568	0	61	theme	Multiple	84:91	arg1	Strategies					107:116	Multiple Anticoagulant Strategies	84:116	Multiple Anticoagulant Strategies	84:116	Construction of the Mussel-Inspired PDAM/Lysine/Heparin Composite Coating Combining Multiple Anticoagulant Strategies.					
37249568	9	62	theme	circulation	1455:1465	arg1	test					1467:1470	the in vitro blood circulation test	1436:1470	the in vitro blood circulation test	1436:1470	Particularly, the anticoagulant coating performed well in the in vitro blood circulation test.					
37249568	4	63	theme	lysine	800:805	arg1	solution					775:782	a mixed solution	767:782	a mixed solution of dopamine and lysine	767:805	First, the PDAM/lysine coating rich in amine groups was constructed in a mixed solution of dopamine and lysine through the co-deposition reaction.					
36430931	12	0	theme	objects	1791:1797	arg1	protection					1754:1763	the protection	1750:1763	the protection of common sterling silver objects	1750:1797	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	10	1	theme	complementary	1472:1484	arg1	information					1486:1496	complementary information	1472:1496	complementary information	1472:1496	Our findings reveal that the two different testing methods provide complementary information.					
36430931	8	2	theme	storage	1137:1143	arg1	conditions					1145:1154	storage conditions	1137:1154	storage conditions	1137:1154	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	11	3	with	comparable	1559:1568	arg1	that					1575:1578	that	1575:1578	that	1575:1578	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	2	4	theme	able	340:343	arg1	materials					329:337	eco-friendly and biocompatible materials	298:337	eco-friendly and biocompatible materials	298:337	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	11	5	theme	protective	1539:1548	arg1	efficacy					1550:1557	protective efficacy	1539:1557	protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer	1539:1660	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	9	6	theme	structural	1240:1249	arg1	analyses					1251:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	0	7	theme	Protective	97:106	arg1	Coatings					108:115	Chitosan-Based Protective Coatings	82:115	Chitosan-Based Protective Coatings	82:115	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	9	8	theme	coatings	1315:1322	arg1	properties					1297:1306	the protective properties	1282:1306	the protective properties of the coatings	1282:1322	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	5	9	used	used	712:715	arg2	product					677:683	A commercial product	664:683	A commercial product based on acrylic resin	664:706	A commercial product based on acrylic resin was used as a reference.					
36430931	5	9	used	used	712:715	arg2	reference					722:730	a reference	720:730	a reference	720:730	A commercial product based on acrylic resin was used as a reference.					
36430931	6	10	theme	coatings	791:798	arg1	features					747:754	aesthetic features	737:754	aesthetic features	737:754	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	6	10	theme	coatings	791:798	arg1	properties					771:780	protective properties	760:780	protective properties	760:780	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	2	11	theme	protective	269:278	arg1	coatings					280:287	protective coatings	269:287	protective coatings	269:287	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	0	12	dep	Development	52:62	arg1	Green					9:13	a Green and Sustainable Silver Conservation	7:49	Green	9:13	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	0	12	dep	Development	52:62	arg1	Conservation					38:49	a Green and Sustainable Silver Conservation	7:49	Conservation	38:49	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	4	13	theme	pure	560:563	arg1	coatings					603:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings were prepared and applied on sterling silver disks.					
36430931	0	14	theme	Chitosan-Based	82:95	arg1	Coatings					108:115	Chitosan-Based Protective Coatings	82:115	Chitosan-Based Protective Coatings	82:115	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	10	15	theme	testing	1448:1454	arg1	methods					1456:1462	the two different testing methods	1430:1462	the two different testing methods	1430:1462	Our findings reveal that the two different testing methods provide complementary information.					
36430931	12	16	theme	sterling	1775:1782	arg1	objects					1791:1797	common sterling silver objects	1768:1797	common sterling silver objects	1768:1797	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	2	17	dep	able	340:343	arg1	hinder					380:385	hinder	380:385	to hinder the degradation of silver objects	377:419	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	2	17	dep	able	340:343	arg1	ensure					348:353	ensure	348:353	to ensure high transparency	345:371	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	10	18	theme	different	1438:1446	arg1	methods					1456:1462	the two different testing methods	1430:1462	the two different testing methods	1430:1462	Our findings reveal that the two different testing methods provide complementary information.					
36430931	3	19	theme	first	489:493	arg1	time					495:498	the first time	485:498	the first time	485:498	In this study, chitosan was used for the first time to realize sustainable coatings for silver protection.					
36430931	6	20	dep	features	747:754	arg1	The					733:735	The	733:735	The	733:735	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	4	21	theme	sterling	641:648	arg1	disks					657:661	sterling silver disks	641:661	sterling silver disks	641:661	Both pure and benzotriazole-containing chitosan coatings were prepared and applied on sterling silver disks.					
36430931	0	22	theme	Coatings	108:115	arg1	Validation					68:77	Validation	68:77	Validation	68:77	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	0	22	theme	Coatings	108:115	arg1	Development					52:62	Development	52:62	Development	52:62	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	11	23	theme	non-toxic	1616:1624	arg1	solvents					1626:1633	non-toxic solvents	1616:1633	non-toxic solvents	1616:1633	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	7	24	theme	efficacy	918:925	arg1	assessment					889:898	the assessment	885:898	the assessment of the protective efficacy	885:925	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	7	25	theme	polluted	981:988	arg1	environments					990:1001	polluted environments	981:1001	polluted environments	981:1001	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	1	26	theme	unpleasant	167:176	arg1	loss					198:201	an unpleasant darkening and shiny loss	164:201	an unpleasant darkening and shiny loss	164:201	When exposed to air, silver artifacts undergo an unpleasant darkening and shiny loss, commonly known as tarnishing.					
36430931	8	27	theme	comparable	1186:1195	arg1	efficacy					1197:1204	comparable efficacy	1186:1204	comparable efficacy	1186:1204	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	6	28	theme	treatments	858:867	arg1	types					843:847	two different types	829:847	two different types of aging treatments	829:867	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	6	29	theme	protective	760:769	arg1	properties					771:780	protective properties	760:780	protective properties	760:780	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	2	30	theme	eco-friendly	298:309	arg1	materials					329:337	eco-friendly and biocompatible materials	298:337	eco-friendly and biocompatible materials	298:337	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	1	31	theme	darkening	178:186	arg1	loss					198:201	an unpleasant darkening and shiny loss	164:201	an unpleasant darkening and shiny loss	164:201	When exposed to air, silver artifacts undergo an unpleasant darkening and shiny loss, commonly known as tarnishing.					
36430931	9	32	theme	physical	1342:1349	arg1	modifications					1363:1375	any physical or chemical modifications	1338:1375	any physical or chemical modifications after the aging treatments	1338:1402	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	8	33	theme	first	1053:1057	arg1	case					1059:1062	the first case	1049:1062	the first case	1049:1062	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	9	34	theme	morphological	1222:1234	arg1	analyses					1251:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	3	35	theme	silver	536:541	arg1	protection					543:552	silver protection	536:552	silver protection	536:552	In this study, chitosan was used for the first time to realize sustainable coatings for silver protection.					
36430931	4	36	theme	silver	650:655	arg1	disks					657:661	sterling silver disks	641:661	sterling silver disks	641:661	Both pure and benzotriazole-containing chitosan coatings were prepared and applied on sterling silver disks.					
36430931	8	37	dep	performed	1108:1116	arg1	whereas					1126:1132	whereas	1126:1132	whereas	1126:1132	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	8	38	theme	chitosan-based	1065:1078	arg1	coatings					1080:1087	chitosan-based coatings	1065:1087	chitosan-based coatings with benzotriazole	1065:1106	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	7	39	theme	protective	907:916	arg1	efficacy					918:925	the protective efficacy	903:925	the protective efficacy	903:925	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	3	40	theme	sustainable	511:521	arg1	coatings					523:530	sustainable coatings	511:530	sustainable coatings	511:530	In this study, chitosan was used for the first time to realize sustainable coatings for silver protection.					
36430931	2	41	theme	silver	406:411	arg1	objects					413:419	silver objects	406:419	silver objects	406:419	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	2	42	theme	objects	413:419	arg1	degradation					391:401	the degradation	387:401	the degradation of silver objects	387:419	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	9	43	theme	chemical	1354:1361	arg1	modifications					1363:1375	any physical or chemical modifications	1338:1375	any physical or chemical modifications after the aging treatments	1338:1402	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	6	44	theme	aging	852:856	arg1	treatments					858:867	aging treatments	852:867	aging treatments	852:867	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	2	45	theme	coatings	280:287	arg1	development					254:264	the development	250:264	the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects,	250:420	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	12	46	theme	cultural	1695:1702	arg1	conservation					1713:1724	cultural heritage conservation	1695:1724	cultural heritage conservation	1695:1724	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	0	47	theme	Silver	31:36	arg1	Conservation					38:49	a Green and Sustainable Silver Conservation	7:49	Conservation	38:49	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	12	48	theme	heritage	1704:1711	arg1	conservation					1713:1724	cultural heritage conservation	1695:1724	cultural heritage conservation	1695:1724	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	5	49	theme	acrylic	694:700	arg1	resin					702:706	acrylic resin	694:706	acrylic resin	694:706	A commercial product based on acrylic resin was used as a reference.					
36430931	12	50	theme	Chitosan	1663:1670	arg1	coatings					1672:1679	Chitosan coatings	1663:1679	Chitosan coatings	1663:1679	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	0	51	theme	Sustainable	19:29	arg1	Conservation					38:49	a Green and Sustainable Silver Conservation	7:49	Conservation	38:49	Toward a Green and Sustainable Silver Conservation: Development and Validation of Chitosan-Based Protective Coatings.					
36430931	6	52	theme	aesthetic	737:745	arg1	features					747:754	aesthetic features	737:754	aesthetic features	737:754	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	8	53	theme	chitosan	1164:1171	arg1	films					1173:1177	all the chitosan films	1156:1177	all the chitosan films	1156:1177	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	9	54	used	used	1265:1268	arg2	analyses					1251:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	6	55	theme	different	833:841	arg1	types					843:847	two different types	829:847	two different types of aging treatments	829:867	The aesthetic features and protective properties of these coatings were evaluated by performing two different types of aging treatments.					
36430931	11	56	theme	renewable	1641:1649	arg1	biopolymer					1651:1660	a renewable biopolymer	1639:1660	a renewable biopolymer	1639:1660	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	2	57	theme	huge	432:435	arg1	challenge					437:445	a huge challenge	430:445	a huge challenge	430:445	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	9	58	theme	aging	1387:1391	arg1	treatments					1393:1402	the aging treatments	1383:1402	the aging treatments	1383:1402	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	12	59	theme	silver	1784:1789	arg1	objects					1791:1797	common sterling silver objects	1768:1797	common sterling silver objects	1768:1797	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	5	60	theme	commercial	666:675	arg1	product					677:683	A commercial product	664:683	A commercial product based on acrylic resin	664:706	A commercial product based on acrylic resin was used as a reference.					
36430931	5	60	theme	commercial	666:675	arg1	reference					722:730	a reference	720:730	a reference	720:730	A commercial product based on acrylic resin was used as a reference.					
36430931	9	61	theme	Compositional	1207:1219	arg1	analyses					1251:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses	1207:1258	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	3	62	used	used	476:479	arg2	chitosan					463:470	chitosan	463:470	chitosan	463:470	In this study, chitosan was used for the first time to realize sustainable coatings for silver protection.					
36430931	11	63	theme	commercial	1587:1596	arg1	product					1598:1604	the commercial product	1583:1604	the commercial product	1583:1604	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	2	64	theme	biocompatible	315:327	arg1	materials					329:337	eco-friendly and biocompatible materials	298:337	eco-friendly and biocompatible materials	298:337	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	8	65	with	coatings	1080:1087	arg1	benzotriazole					1094:1106	benzotriazole	1094:1106	benzotriazole	1094:1106	In the first case, chitosan-based coatings with benzotriazole performed better, whereas in storage conditions all the chitosan films showed comparable efficacy.					
36430931	4	66	theme	benzotriazole-containing	569:592	arg1	coatings					603:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings were prepared and applied on sterling silver disks.					
36430931	7	67	theme	storage	1026:1032	arg1	conditions					1034:1043	both highly aggressive polluted environments and real-like museums' storage conditions	958:1043	both highly aggressive polluted environments and real-like museums' storage conditions	958:1043	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	7	68	theme	real-like	1007:1015	arg1	museums					1017:1023	real-like museums	1007:1023	real-like museums	1007:1023	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	7	69	theme	aggressive	970:979	arg1	conditions					1034:1043	both highly aggressive polluted environments and real-like museums' storage conditions	958:1043	both highly aggressive polluted environments and real-like museums' storage conditions	958:1043	In particular, the assessment of the protective efficacy was carried out by reproducing both highly aggressive polluted environments and real-like museums' storage conditions.					
36430931	11	70	theme	chitosan	1509:1516	arg1	coatings					1518:1525	chitosan coatings	1509:1525	chitosan coatings	1509:1525	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	9	71	theme	protective	1286:1295	arg1	properties					1297:1306	the protective properties	1282:1306	the protective properties of the coatings	1282:1322	Compositional, morphological and structural analyses were used to evaluate the protective properties of the coatings and to detect any physical or chemical modifications after the aging treatments.					
36430931	1	72	theme	shiny	192:196	arg1	loss					198:201	an unpleasant darkening and shiny loss	164:201	an unpleasant darkening and shiny loss	164:201	When exposed to air, silver artifacts undergo an unpleasant darkening and shiny loss, commonly known as tarnishing.					
36430931	2	73	theme	high	355:358	arg1	transparency					360:371	high transparency	355:371	high transparency	355:371	At the present, the development of protective coatings by using eco-friendly and biocompatible materials, able to ensure high transparency and to hinder the degradation of silver objects, remains a huge challenge.					
36430931	12	74	theme	common	1768:1773	arg1	objects					1791:1797	common sterling silver objects	1768:1797	common sterling silver objects	1768:1797	Chitosan coatings, designed for cultural heritage conservation, are thus promising for the protection of common sterling silver objects.					
36430931	1	75	theme	silver	139:144	arg1	artifacts					146:154	silver artifacts	139:154	silver artifacts	139:154	When exposed to air, silver artifacts undergo an unpleasant darkening and shiny loss, commonly known as tarnishing.					
36430931	11	76	theme	comparable	1559:1568	arg1	efficacy					1550:1557	protective efficacy	1539:1557	protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer	1539:1660	Moreover, chitosan coatings can achieve protective efficacy comparable with that of the commercial product but using non-toxic solvents and a renewable biopolymer.					
36430931	4	77	theme	chitosan	594:601	arg1	coatings					603:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings	555:610	Both pure and benzotriazole-containing chitosan coatings were prepared and applied on sterling silver disks.					
36998008	12	0	theme	hydrodynamic	1856:1867	arg1	210 ± 21 nm					1879:1889	210 ± 21 nm	1879:1889	210 ± 21 nm	1879:1889	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	12	0	theme	hydrodynamic	1856:1867	arg1	diameter					1869:1876	hydrodynamic diameter	1856:1876	hydrodynamic diameter (210 ± 21 nm)	1856:1890	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	4	1	theme	prospective	582:592	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	1	theme	prospective	582:592	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	5	2	theme	Chitosan-dextran	687:702	arg1	sulfate					704:710	METHODS Chitosan-dextran sulfate	679:710	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs)	679:736	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	10	3	theme	liquid	1453:1458	arg1	HPLC					1476:1479	HPLC	1476:1479	HPLC	1476:1479	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
36998008	10	3	theme	liquid	1453:1458	arg1	chromatography					1460:1473	high-performance liquid chromatography	1436:1473	high-performance liquid chromatography (HPLC) analysis	1436:1489	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
36998008	12	4	theme	TEM	1824:1826	arg1	images					1828:1833	TEM images	1824:1833	TEM images (145.31 ± 33.15 nm)	1824:1853	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	12	4	theme	TEM	1824:1826	arg1	145.31 ± 33.15 nm					1836:1852	145.31 ± 33.15 nm	1836:1852	145.31 ± 33.15 nm	1836:1852	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	4	5	theme	delivery	599:606	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	5	theme	delivery	599:606	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	7	6	theme	electron	921:928	arg1	TEM					942:944	TEM	942:944	TEM	942:944	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	6	theme	electron	921:928	arg1	microscopy					930:939	Transmission electron microscopy	908:939	Transmission electron microscopy (TEM)	908:945	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	8	7	theme	scanning	1195:1202	arg1	DSC					1217:1219	DSC	1217:1219	DSC	1217:1219	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	8	7	theme	scanning	1195:1202	arg1	calorimetry					1204:1214	Differential scanning calorimetry	1182:1214	Differential scanning calorimetry (DSC)	1182:1220	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	6	8	theme	silica-coated	828:840	arg1	NPs					848:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs were physically characterized via different techniques.					
36998008	2	9	theme	insulin	288:294	arg1	system					305:310	an effective oral insulin delivery system	270:310	an effective oral insulin delivery system using nanotechnology	270:331	Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology.					
36998008	1	10	theme	exciting	192:199	arg1	subjects					210:217	the most exciting research subjects	183:217	the most exciting research subjects	183:217	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	15	11	dep	CONCLUSION	2286:2295	arg1	candidate					2339:2347	an efficient candidate	2326:2347	an efficient candidate as a desired oral delivery system	2326:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	11	dep	CONCLUSION	2286:2295	arg1	ICN					2315:2317	The silica-coated ICN	2297:2317	The silica-coated ICN	2297:2317	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	12	12	theme	particle	1798:1805	arg1	size					1807:1810	suitable core particle size	1784:1810	suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM	1784:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	8	13	theme	nano-formulations	1265:1281	arg1	properties					1244:1253	the thermal properties	1232:1253	the thermal properties of formed nano-formulations	1232:1281	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	6	14	theme	Uncoated	815:822	arg1	NPs					848:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs were physically characterized via different techniques.					
36998008	1	15	theme	subjects	210:217	arg1	one					176:178	one	176:178	one	176:178	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	1	15	theme	subjects	210:217	arg1	subjects					210:217	the most exciting research subjects	183:217	the most exciting research subjects	183:217	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	14	16	theme	insulin	2215:2221	arg1	profile					2231:2237	a controlled insulin release profile	2202:2237	a controlled insulin release profile	2202:2237	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	7	17	theme	chemical	1092:1099	arg1	size					1111:1114	size	1111:1114	size	1111:1114	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	17	theme	chemical	1092:1099	arg1	elements					1101:1108	the chemical elements	1088:1108	the chemical elements	1088:1108	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	17	theme	chemical	1092:1099	arg1	properties					1141:1150	surface properties	1133:1150	surface properties	1133:1150	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	17	theme	chemical	1092:1099	arg1	morphology					1117:1126	morphology	1117:1126	morphology	1117:1126	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	15	18	theme	further	2506:2512	arg1	applications					2514:2525	further applications	2506:2525	further applications	2506:2525	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	7	19	theme	formulations	1168:1179	arg1	size					1111:1114	size	1111:1114	size	1111:1114	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	19	theme	formulations	1168:1179	arg1	properties					1141:1150	surface properties	1133:1150	surface properties	1133:1150	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	19	theme	formulations	1168:1179	arg1	elements					1101:1108	the chemical elements	1088:1108	the chemical elements	1088:1108	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	19	theme	formulations	1168:1179	arg1	morphology					1117:1126	morphology	1117:1126	morphology	1117:1126	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	8	20	theme	thermal	1236:1242	arg1	properties					1244:1253	the thermal properties	1232:1253	the thermal properties of formed nano-formulations	1232:1281	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	13	21	theme	complex	2137:2143	arg1	ICCN					2160:2163	ICCN	2160:2163	ICCN	2160:2163	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	21	theme	complex	2137:2143	arg1	nanoparticles					2145:2157	insulin-chitosan complex nanoparticles	2120:2157	insulin-chitosan complex nanoparticles (ICCN)	2120:2164	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	7	22	theme	surface	1133:1139	arg1	properties					1141:1150	surface properties	1133:1150	surface properties	1133:1150	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	22	theme	surface	1133:1139	arg1	elements					1101:1108	the chemical elements	1088:1108	the chemical elements	1088:1108	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	23	theme	force	1035:1039	arg1	microscopy					1041:1050	atomic force microscopy	1028:1050	atomic force microscopy (AFM)	1028:1056	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	23	theme	force	1035:1039	arg1	AFM					1053:1055	AFM	1053:1055	AFM	1053:1055	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	13	24	theme	encapsulation	2016:2028	arg1	higher					2100:2105	higher	2100:2105	higher	2100:2105	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	24	theme	encapsulation	2016:2028	arg1	efficiency					2030:2039	The encapsulation efficiency	2012:2039	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN)	2012:2086	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	15	25	theme	delivery	2367:2374	arg1	system					2376:2381	a desired oral delivery system	2352:2381	a desired oral delivery system	2352:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	2	26	theme	effective	273:281	arg1	system					305:310	an effective oral insulin delivery system	270:310	an effective oral insulin delivery system using nanotechnology	270:331	Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology.					
36998008	12	27	theme	core	1793:1796	arg1	size					1807:1810	suitable core particle size	1784:1810	suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM	1784:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	3	28	theme	delivery	355:362	arg1	system					364:369	a delivery system	353:369	a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects	353:483	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	15	29	theme	high	2464:2467	arg1	stability					2469:2477	high stability	2464:2477	high stability	2464:2477	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	12	30	theme	interesting	1730:1740	arg1	properties					1758:1767	interesting physicochemical properties	1730:1767	interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM	1730:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	14	31	theme	silica-coated	2171:2183	arg1	ICN					2185:2187	The silica-coated ICN	2167:2187	The silica-coated ICN	2167:2187	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	0	32	theme	oral	89:92	arg1	administration					94:107	a promising oral administration	77:107	a promising oral administration system	77:114	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	7	33	theme	EDX	1009:1011	arg1	analysis					1014:1021	energy-dispersive X-ray (EDX) analysis	984:1021	energy-dispersive X-ray (EDX) analysis	984:1021	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	11	34	theme	silica	1572:1577	arg1	coat					1579:1582	silica coat	1572:1582	silica coat	1572:1582	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	5	35	theme	coacervation	766:777	arg1	method					779:784	a complex coacervation method	756:784	a complex coacervation method	756:784	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	15	36	theme	proteins	2432:2439	arg1	obstacles					2406:2414	the common obstacles	2395:2414	the common obstacles of peptides and proteins delivery	2395:2448	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	12	37	theme	surface	1977:1983	arg1	roughness					1985:1993	adequate surface roughness	1968:1993	adequate surface roughness assessed by AFM	1968:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	7	38	theme	X-ray	1002:1006	arg1	analysis					1014:1021	energy-dispersive X-ray (EDX) analysis	984:1021	energy-dispersive X-ray (EDX) analysis	984:1021	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	12	39	theme	silica-coated	1697:1709	arg1	NPs					1717:1719	The silica-coated CS-DS NPs	1693:1719	RESULTS The silica-coated CS-DS NPs	1685:1719	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	11	40	theme	insulin	1496:1502	arg1	profile					1512:1518	The insulin release profile	1492:1518	The insulin release profile of nano-formulations	1492:1539	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	3	41	theme	side	472:475	arg1	effects					477:483	minimal side effects	464:483	minimal side effects	464:483	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	4	42	theme	drug	594:597	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	42	theme	drug	594:597	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	9	43	theme	silica	1349:1354	arg1	coat					1356:1359	the silica coat and chitosan interaction	1345:1384	coat	1356:1359	Fourier transform infrared (FT-IR) spectroscopy investigated the silica coat and chitosan interaction.					
36998008	3	44	theme	insulin	411:417	arg1	administration					419:432	oral insulin administration	406:432	oral insulin administration	406:432	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	0	45	theme	Controlled	0:9	arg1	release					11:17	Controlled release	0:17	Controlled release of silica-coated insulin-loaded chitosan	0:58	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	4	46	theme	efforts	558:564	arg1	one					547:549	one	547:549	one	547:549	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	46	theme	efforts	558:564	arg1	efforts					558:564	the efforts	554:564	the efforts	554:564	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	11	47	theme	different	1591:1599	arg1	pHs					1601:1603	two different pHs	1587:1603	two different pHs (5.5,7)	1587:1611	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	11	47	theme	different	1591:1599	arg1	5.5,7					1606:1610	5.5,7	1606:1610	5.5,7	1606:1610	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	11	48	theme	nano-formulations	1523:1539	arg1	profile					1512:1518	The insulin release profile	1492:1518	The insulin release profile of nano-formulations	1492:1539	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	1	49	theme	Oral	128:131	arg1	administration					141:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	3	50	theme	high	445:448	arg1	stability					450:458	high stability	445:458	high stability	445:458	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	14	51	theme	uncoated	2272:2279	arg1	ICN					2281:2283	uncoated ICN	2272:2283	uncoated ICN	2272:2283	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	0	52	theme	insulin-loaded	36:49	arg1	chitosan					51:58	silica-coated insulin-loaded chitosan	22:58	silica-coated insulin-loaded chitosan	22:58	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	7	53	theme	prepared	1159:1166	arg1	formulations					1168:1179	the prepared formulations	1155:1179	the prepared formulations	1155:1179	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	13	54	dep	higher	2100:2105	arg1	%					2097:2097	66.5%	2093:2097	66.5%	2093:2097	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	14	55	dep	pHs	2242:2244	arg1	5.5					2247:2249	5.5	2247:2249	5.5	2247:2249	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	14	55	dep	pHs	2242:2244	arg1	7					2255:2255	7	2255:2255	7	2255:2255	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	12	56	theme	potential	1932:1940	arg1	-32 ± 3.2 mV					1949:1960	-32 ± 3.2 mV	1949:1960	-32 ± 3.2 mV	1949:1960	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	12	56	theme	potential	1932:1940	arg1	value					1942:1946	their zeta potential value	1921:1946	their zeta potential value (-32 ± 3.2 mV)	1921:1961	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	12	57	theme	high	1893:1896	arg1	stability					1898:1906	high stability	1893:1906	high stability indicated by their zeta potential value (-32 ± 3.2 mV)	1893:1961	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	3	58	theme	urgent	498:503	arg1	need					505:508	an urgent need	495:508	an urgent need	495:508	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	3	58	theme	urgent	498:503	arg1	development					338:348	The development	334:348	The development	334:348	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	15	59	theme	desired	2354:2360	arg1	system					2376:2381	a desired oral delivery system	2352:2381	a desired oral delivery system	2352:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	13	60	theme	chitosan	2059:2066	arg1	nanoparticles					2068:2080	insulin-loaded chitosan nanoparticles	2044:2080	insulin-loaded chitosan nanoparticles (ICN)	2044:2086	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	60	theme	chitosan	2059:2066	arg1	ICN					2083:2085	ICN	2083:2085	ICN	2083:2085	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	7	61	theme	electron	957:964	arg1	SEM					978:980	SEM	978:980	SEM	978:980	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	61	theme	electron	957:964	arg1	microscopy					966:975	scanning electron microscopy	948:975	scanning electron microscopy (SEM)	948:981	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	4	62	theme	silica-coated	624:636	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	62	theme	silica-coated	624:636	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	5	63	theme	METHODS	679:685	arg1	sulfate					704:710	METHODS Chitosan-dextran sulfate	679:710	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs)	679:736	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	11	64	theme	gastrointestinal	1655:1670	arg1	GIT					1679:1681	GIT	1679:1681	GIT	1679:1681	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	11	64	theme	gastrointestinal	1655:1670	arg1	tract					1672:1676	the gastrointestinal tract	1651:1676	the gastrointestinal tract (GIT)	1651:1682	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	15	65	theme	efficient	2329:2337	arg1	candidate					2339:2347	an efficient candidate	2326:2347	an efficient candidate as a desired oral delivery system	2326:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	65	theme	efficient	2329:2337	arg1	ICN					2315:2317	The silica-coated ICN	2297:2317	The silica-coated ICN	2297:2317	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	4	66	theme	new	578:580	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	66	theme	new	578:580	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	5	67	theme	sulfate	704:710	arg1	NPs					733:735	CS-DS NPs	727:735	CS-DS NPs	727:735	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	5	67	theme	sulfate	704:710	arg1	nanoparticles					712:724	METHODS Chitosan-dextran sulfate nanoparticles	679:724	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs)	679:736	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	10	68	theme	high-performance	1436:1451	arg1	HPLC					1476:1479	HPLC	1476:1479	HPLC	1476:1479	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
36998008	10	68	theme	high-performance	1436:1451	arg1	chromatography					1460:1473	high-performance liquid chromatography	1436:1473	high-performance liquid chromatography (HPLC) analysis	1436:1489	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
36998008	9	69	dep	Fourier	1284:1290	arg1	transform					1292:1300	transform	1292:1300	transform infrared (FT-IR) spectroscopy	1292:1330	Fourier transform infrared (FT-IR) spectroscopy investigated the silica coat and chitosan interaction.					
36998008	6	70	theme	CS-DS	842:846	arg1	NPs					848:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs	815:850	Uncoated and silica-coated CS-DS NPs were physically characterized via different techniques.					
36998008	2	71	theme	delivery	296:303	arg1	system					305:310	an effective oral insulin delivery system	270:310	an effective oral insulin delivery system using nanotechnology	270:331	Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology.					
36998008	8	72	theme	Differential	1182:1193	arg1	DSC					1217:1219	DSC	1217:1219	DSC	1217:1219	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	8	72	theme	Differential	1182:1193	arg1	calorimetry					1204:1214	Differential scanning calorimetry	1182:1214	Differential scanning calorimetry (DSC)	1182:1220	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	7	73	theme	Transmission	908:919	arg1	TEM					942:944	TEM	942:944	TEM	942:944	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	73	theme	Transmission	908:919	arg1	microscopy					930:939	Transmission electron microscopy	908:939	Transmission electron microscopy (TEM)	908:945	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	1	74	theme	research	201:208	arg1	subjects					210:217	the most exciting research subjects	183:217	the most exciting research subjects	183:217	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	8	75	theme	formed	1258:1263	arg1	nano-formulations					1265:1281	formed nano-formulations	1258:1281	formed nano-formulations	1258:1281	Differential scanning calorimetry (DSC) to assess the thermal properties of formed nano-formulations.					
36998008	14	76	theme	release	2223:2229	arg1	profile					2231:2237	a controlled insulin release profile	2202:2237	a controlled insulin release profile	2202:2237	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	10	77	theme	chromatography	1460:1473	arg1	analysis					1482:1489	high-performance liquid chromatography (HPLC) analysis	1436:1489	high-performance liquid chromatography (HPLC) analysis	1436:1489	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
36998008	4	78	theme	sulfate	655:661	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	78	theme	sulfate	655:661	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	14	79	theme	controlled	2204:2213	arg1	profile					2231:2237	a controlled insulin release profile	2202:2237	a controlled insulin release profile	2202:2237	The silica-coated ICN demonstrated a controlled insulin release profile at pHs (5.5 and 7) compared with uncoated ICN.					
36998008	15	80	dep	peptides	2419:2426	arg1	delivery					2441:2448	delivery	2441:2448	delivery	2441:2448	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	81	theme	common	2399:2404	arg1	obstacles					2406:2414	the common obstacles	2395:2414	the common obstacles of peptides and proteins delivery	2395:2448	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	1	82	theme	insulin	133:139	arg1	administration					141:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	2	83	theme	oral	283:286	arg1	system					305:310	an effective oral insulin delivery system	270:310	an effective oral insulin delivery system using nanotechnology	270:331	Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology.					
36998008	0	84	theme	promising	79:87	arg1	administration					94:107	a promising oral administration	77:107	a promising oral administration system	77:114	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	9	85	theme	infrared	1302:1309	arg1	spectroscopy					1319:1330	infrared (FT-IR) spectroscopy	1302:1330	infrared (FT-IR) spectroscopy	1302:1330	Fourier transform infrared (FT-IR) spectroscopy investigated the silica coat and chitosan interaction.					
36998008	7	86	theme	atomic	1028:1033	arg1	microscopy					1041:1050	atomic force microscopy	1028:1050	atomic force microscopy (AFM)	1028:1056	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	86	theme	atomic	1028:1033	arg1	AFM					1053:1055	AFM	1053:1055	AFM	1053:1055	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	12	87	theme	suitable	1784:1791	arg1	size					1807:1810	suitable core particle size	1784:1810	suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM	1784:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	3	88	theme	system	364:369	arg1	need					505:508	an urgent need	495:508	an urgent need	495:508	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	3	88	theme	system	364:369	arg1	development					338:348	The development	334:348	The development	334:348	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	0	89	theme	administration	94:107	arg1	system					109:114	a promising oral administration system	77:114	a promising oral administration system	77:114	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	9	90	theme	FT-IR	1312:1316	arg1	spectroscopy					1319:1330	infrared (FT-IR) spectroscopy	1302:1330	infrared (FT-IR) spectroscopy	1302:1330	Fourier transform infrared (FT-IR) spectroscopy investigated the silica coat and chitosan interaction.					
36998008	12	91	theme	adequate	1968:1975	arg1	roughness					1985:1993	adequate surface roughness	1968:1993	adequate surface roughness assessed by AFM	1968:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	15	92	theme	controlled	2483:2492	arg1	release					2494:2500	controlled release	2483:2500	controlled release	2483:2500	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	5	93	theme	complex	758:764	arg1	coacervation					766:777	a complex coacervation	756:777	a complex coacervation method	756:784	METHODS Chitosan-dextran sulfate nanoparticles (CS-DS NPs) were prepared via a complex coacervation method and then coated with silica.					
36998008	13	94	theme	insulin-chitosan	2120:2135	arg1	ICCN					2160:2163	ICCN	2160:2163	ICCN	2160:2163	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	94	theme	insulin-chitosan	2120:2135	arg1	nanoparticles					2145:2157	insulin-chitosan complex nanoparticles	2120:2157	insulin-chitosan complex nanoparticles (ICCN)	2120:2164	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	12	95	theme	physicochemical	1742:1756	arg1	properties					1758:1767	interesting physicochemical properties	1730:1767	interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM	1730:2009	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	13	96	theme	insulin-loaded	2044:2057	arg1	nanoparticles					2068:2080	insulin-loaded chitosan nanoparticles	2044:2080	insulin-loaded chitosan nanoparticles (ICN)	2044:2086	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	96	theme	insulin-loaded	2044:2057	arg1	ICN					2083:2085	ICN	2083:2085	ICN	2083:2085	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	7	97	theme	energy-dispersive	984:1000	arg1	analysis					1014:1021	energy-dispersive X-ray (EDX) analysis	984:1021	energy-dispersive X-ray (EDX) analysis	984:1021	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	12	98	theme	CS-DS	1711:1715	arg1	NPs					1717:1719	The silica-coated CS-DS NPs	1693:1719	RESULTS The silica-coated CS-DS NPs	1685:1719	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	3	99	theme	administration	419:432	arg1	difficulties					390:401	the difficulties	386:401	the difficulties of oral insulin administration	386:432	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	3	100	theme	minimal	464:470	arg1	effects					477:483	minimal side effects	464:483	minimal side effects	464:483	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	0	101	theme	silica-coated	22:34	arg1	chitosan					51:58	silica-coated insulin-loaded chitosan	22:58	silica-coated insulin-loaded chitosan	22:58	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	9	102	theme	chitosan	1365:1372	arg1	interaction					1374:1384	the silica coat and chitosan interaction	1345:1384	interaction	1374:1384	Fourier transform infrared (FT-IR) spectroscopy investigated the silica coat and chitosan interaction.					
36998008	12	103	theme	zeta	1927:1930	arg1	-32 ± 3.2 mV					1949:1960	-32 ± 3.2 mV	1949:1960	-32 ± 3.2 mV	1949:1960	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	12	103	theme	zeta	1927:1930	arg1	value					1942:1946	their zeta potential value	1921:1946	their zeta potential value (-32 ± 3.2 mV)	1921:1961	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	1	104	theme	BACKGROUND	117:126	arg1	administration					141:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration	117:154	BACKGROUND Oral insulin administration has recently become one of the most exciting research subjects.					
36998008	3	105	theme	oral	406:409	arg1	administration					419:432	oral insulin administration	406:432	oral insulin administration	406:432	The development of a delivery system that overcomes the difficulties of oral insulin administration, achieving high stability and minimal side effects, is still an urgent need.					
36998008	11	106	theme	release	1504:1510	arg1	profile					1512:1518	The insulin release profile	1492:1518	The insulin release profile of nano-formulations	1492:1539	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	0	107	theme	chitosan	51:58	arg1	release					11:17	Controlled release	0:17	Controlled release of silica-coated insulin-loaded chitosan	0:58	Controlled release of silica-coated insulin-loaded chitosan nanoparticles as a promising oral administration system.					
36998008	15	108	theme	silica-coated	2301:2313	arg1	candidate					2339:2347	an efficient candidate	2326:2347	an efficient candidate as a desired oral delivery system	2326:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	108	theme	silica-coated	2301:2313	arg1	ICN					2315:2317	The silica-coated ICN	2297:2317	The silica-coated ICN	2297:2317	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	12	109	dep	RESULTS	1685:1691	arg1	NPs					1717:1719	The silica-coated CS-DS NPs	1693:1719	RESULTS The silica-coated CS-DS NPs	1685:1719	RESULTS The silica-coated CS-DS NPs revealed interesting physicochemical properties exemplified by suitable core particle size obtained by TEM images (145.31 ± 33.15 nm), hydrodynamic diameter (210 ± 21 nm), high stability indicated by their zeta potential value (-32 ± 3.2 mV), and adequate surface roughness assessed by AFM.					
36998008	15	110	theme	peptides	2419:2426	arg1	obstacles					2406:2414	the common obstacles	2395:2414	the common obstacles of peptides and proteins delivery	2395:2448	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	6	111	theme	different	886:894	arg1	techniques					896:905	different techniques	886:905	different techniques	886:905	Uncoated and silica-coated CS-DS NPs were physically characterized via different techniques.					
36998008	13	112	theme	nanoparticles	2068:2080	arg1	higher					2100:2105	higher	2100:2105	higher	2100:2105	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	13	112	theme	nanoparticles	2068:2080	arg1	efficiency					2030:2039	The encapsulation efficiency	2012:2039	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN)	2012:2086	The encapsulation efficiency of insulin-loaded chitosan nanoparticles (ICN) was (66.5%) higher than that of insulin-chitosan complex nanoparticles (ICCN).					
36998008	2	113	theme	Different	220:228	arg1	approaches					230:239	Different approaches	220:239	Different approaches	220:239	Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology.					
36998008	11	114	theme	tract	1672:1676	arg1	environment					1636:1646	the environment	1632:1646	the environment of the gastrointestinal tract (GIT)	1632:1682	The insulin release profile of nano-formulations was performed with and without silica coat at two different pHs (5.5,7), nearly simulating the environment of the gastrointestinal tract (GIT).					
36998008	7	115	theme	scanning	948:955	arg1	SEM					978:980	SEM	978:980	SEM	978:980	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	115	theme	scanning	948:955	arg1	microscopy					966:975	scanning electron microscopy	948:975	scanning electron microscopy (SEM)	948:981	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	15	116	theme	oral	2362:2365	arg1	system					2376:2381	a desired oral delivery system	2352:2381	a desired oral delivery system	2352:2381	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	117	dep	candidate	2339:2347	arg1	achieving					2454:2462	achieving	2454:2462	achieving high stability and controlled release for further applications	2454:2525	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	15	117	dep	candidate	2339:2347	arg1	overcoming					2384:2393	overcoming	2384:2393	overcoming the common obstacles of peptides and proteins delivery	2384:2448	CONCLUSION The silica-coated ICN can be an efficient candidate as a desired oral delivery system, overcoming the common obstacles of peptides and proteins delivery and achieving high stability and controlled release for further applications.					
36998008	4	118	theme	chitosan-dextran	638:653	arg1	nanoparticles					663:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	silica-coated chitosan-dextran sulfate nanoparticles	624:675	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	4	118	theme	chitosan-dextran	638:653	arg1	nano-composite					608:621	a new prospective drug delivery nano-composite	576:621	a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles)	576:676	Therefore, this study is considered one of the efforts to design a new prospective drug delivery nano-composite (silica-coated chitosan-dextran sulfate nanoparticles).					
36998008	7	119	used	used	1068:1071	arg2	AFM					1053:1055	AFM	1053:1055	AFM	1053:1055	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	microscopy					930:939	Transmission electron microscopy	908:939	Transmission electron microscopy (TEM)	908:945	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	SEM					978:980	SEM	978:980	SEM	978:980	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	analysis					1014:1021	energy-dispersive X-ray (EDX) analysis	984:1021	energy-dispersive X-ray (EDX) analysis	984:1021	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	microscopy					966:975	scanning electron microscopy	948:975	scanning electron microscopy (SEM)	948:981	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	microscopy					1041:1050	atomic force microscopy	1028:1050	atomic force microscopy (AFM)	1028:1056	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	7	119	used	used	1068:1071	arg2	TEM					942:944	TEM	942:944	TEM	942:944	Transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) analysis, and atomic force microscopy (AFM) have been used to investigate the chemical elements, size, morphology, and surface properties of the prepared formulations.					
36998008	10	120	theme	encapsulation	1391:1403	arg1	efficiency					1405:1414	The encapsulation efficiency	1387:1414	The encapsulation efficiency	1387:1414	The encapsulation efficiency was evaluated using high-performance liquid chromatography (HPLC) analysis.					
37105254	9	0	theme	expands	1450:1456	arg1	detection					1420:1428	the detection	1416:1428	the detection of Au3+ and further expands the application field of agroforestry waste	1416:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	6	1	theme	response	937:944	arg1	time					946:949	a short response time	929:949	a short response time	929:949	Moreover, it is highly resistant to interference and has a short response time, which can be rapidly responded within 1 min.					
37105254	7	2	theme	fluorescence	1124:1135	arg1	consistent					1187:1196	consistent	1187:1196	consistent	1187:1196	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	7	2	theme	fluorescence	1124:1135	arg1	effect					1137:1142	the fluorescence effect	1120:1142	the fluorescence effect shown by the fluorescent composite film	1120:1182	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	9	3	theme	Au3+	1433:1436	arg1	expands					1450:1456	Au3+ and further expands	1433:1456	Au3+ and further expands the application field of agroforestry waste	1433:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	1	4	theme	corn	150:153	arg1	probe					189:193	a corn bract cellulose-based fluorescent probe	148:193	a corn bract cellulose-based fluorescent probe MAC-1 for	148:203	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	6	5	theme	short	931:935	arg1	time					946:949	a short response time	929:949	a short response time	929:949	Moreover, it is highly resistant to interference and has a short response time, which can be rapidly responded within 1 min.					
37105254	7	6	theme	MAC-1	1240:1244	arg1	change					1220:1225	the fluorescence change	1203:1225	the fluorescence change of the probe MAC-1 itself	1203:1251	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	7	7	theme	practical	1025:1033	arg1	application					1035:1045	the practical application	1021:1045	the practical application of the probe	1021:1058	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	5	8	theme	high	833:836	arg1	selectivity					838:848	high selectivity	833:848	high selectivity	833:848	The results showed that the recognition of Au3+ by the probe MAC-1 exhibited high selectivity and high sensitivity.					
37105254	8	9	theme	mechanical	1346:1355	arg1	properties					1357:1366	good overall physical and mechanical properties	1320:1366	good overall physical and mechanical properties	1320:1366	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	0	10	theme	composite	86:94	arg1	membranes					96:104	composite membranes	86:104	composite membranes	86:104	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	0	11	from	probe	57:61	arg1	membranes					96:104	composite membranes	86:104	composite membranes	86:104	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	4	12	theme	fluorescence	724:735	arg1	spectrophotometer					737:753	fluorescence spectrophotometer	724:753	fluorescence spectrophotometer	724:753	The fluorescence properties of the probe were also characterized by UV spectrophotometer and fluorescence spectrophotometer.					
37105254	3	13	dep	FTIR	501:504	arg1	transform					515:523	transform	515:523	transform infrared spectroscopy	515:545	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	7	14	theme	fluorescent	1089:1099	arg1	film					1111:1114	a fluorescent composite film	1087:1114	a fluorescent composite film	1087:1114	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	7	14	theme	fluorescent	1089:1099	arg1	probe					1065:1069	the probe	1061:1069	the probe	1061:1069	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	4	15	theme	fluorescence	635:646	arg1	properties					648:657	The fluorescence properties	631:657	The fluorescence properties of the probe	631:670	The fluorescence properties of the probe were also characterized by UV spectrophotometer and fluorescence spectrophotometer.					
37105254	9	16	theme	meaningful	1391:1400	arg1	reference					1402:1410	a meaningful reference	1389:1410	a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste	1389:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	2	17	theme	1:9	276:278	arg1	solution					296:303	DMF-H2O (1:9, v/v, pH = 7.4) solution	267:303	solution	296:303	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	2	18	theme	quenching	357:365	arg1	properties					380:389	quenching fluorescence properties	357:389	quenching fluorescence properties for Au3+	357:398	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	1	19	theme	bract	155:159	arg1	probe					189:193	a corn bract cellulose-based fluorescent probe	148:193	a corn bract cellulose-based fluorescent probe MAC-1 for	148:203	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	7	20	theme	composite	1101:1109	arg1	film					1111:1114	a fluorescent composite film	1087:1114	a fluorescent composite film	1087:1114	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	7	20	theme	composite	1101:1109	arg1	probe					1065:1069	the probe	1061:1069	the probe	1061:1069	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	4	21	theme	UV	699:700	arg1	spectrophotometer					702:718	UV spectrophotometer	699:718	UV spectrophotometer	699:718	The fluorescence properties of the probe were also characterized by UV spectrophotometer and fluorescence spectrophotometer.					
37105254	2	22	theme	fluorescence	367:378	arg1	properties					380:389	quenching fluorescence properties	357:389	quenching fluorescence properties for Au3+	357:398	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	7	23	with	consistent	1187:1196	arg1	change					1220:1225	the fluorescence change	1203:1225	the fluorescence change of the probe MAC-1 itself	1203:1251	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	9	24	theme	agroforestry	1483:1494	arg1	waste					1496:1500	agroforestry waste	1483:1500	agroforestry waste	1483:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	4	25	theme	probe	666:670	arg1	properties					648:657	The fluorescence properties	631:657	The fluorescence properties of the probe	631:670	The fluorescence properties of the probe were also characterized by UV spectrophotometer and fluorescence spectrophotometer.					
37105254	9	26	dep	expands	1450:1456	arg1	field					1474:1478	the application field	1458:1478	Au3+ and further expands the application field of agroforestry waste	1433:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	1	27	theme	fluorescent	177:187	arg1	probe					189:193	a corn bract cellulose-based fluorescent probe	148:193	a corn bract cellulose-based fluorescent probe MAC-1 for	148:203	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	9	28	theme	waste	1496:1500	arg1	field					1474:1478	the application field	1458:1478	Au3+ and further expands the application field of agroforestry waste	1433:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	3	29	theme	infrared	525:532	arg1	spectroscopy					534:545	infrared spectroscopy	525:545	infrared spectroscopy	525:545	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	7	30	theme	probe	1234:1238	arg1	MAC-1					1240:1244	the probe MAC-1 itself	1230:1251	the probe MAC-1 itself	1230:1251	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	0	31	theme	bract	18:22	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of corn bract	0:22	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	5	32	theme	high	854:857	arg1	sensitivity					859:869	high sensitivity	854:869	high sensitivity	854:869	The results showed that the recognition of Au3+ by the probe MAC-1 exhibited high selectivity and high sensitivity.					
37105254	8	33	theme	excellent	1294:1302	arg1	selectivity					1304:1314	excellent selectivity	1294:1314	excellent selectivity	1294:1314	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	0	34	theme	corn	13:16	arg1	bract					18:22	corn bract	13:22	corn bract	13:22	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	8	35	theme	composite	1270:1278	arg1	film					1280:1283	The fluorescent composite film	1254:1283	The fluorescent composite film	1254:1283	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	2	36	theme	emission	328:335	arg1	peak					337:340	a fluorescence emission peak	313:340	a fluorescence emission peak	313:340	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	7	37	theme	fluorescent	1157:1167	arg1	film					1179:1182	the fluorescent composite film	1153:1182	the fluorescent composite film	1153:1182	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	0	38	theme	Au3+	40:43	arg1	probe					57:61	Au3+ fluorescent probe	40:61	Au3+ fluorescent probe	40:61	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	7	39	theme	fluorescence	1207:1218	arg1	change					1220:1225	the fluorescence change	1203:1225	the fluorescence change of the probe MAC-1 itself	1203:1251	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	0	40	from	application	71:81	arg1	membranes					96:104	composite membranes	86:104	composite membranes	86:104	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	2	41	theme	good	235:238	arg1	properties					253:262	good fluorescence properties	235:262	good fluorescence properties	235:262	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	3	42	theme	MAC-1	418:422	arg1	structure					405:413	The structure	401:413	The structure of MAC-1	401:422	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	5	43	theme	probe	811:815	arg1	MAC-1					817:821	the probe MAC-1	807:821	the probe MAC-1	807:821	The results showed that the recognition of Au3+ by the probe MAC-1 exhibited high selectivity and high sensitivity.					
37105254	1	44	dep	probe	189:193	arg1	MAC-1					195:199	MAC-1	195:199	a corn bract cellulose-based fluorescent probe MAC-1 for	148:203	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	2	45	dep	showed	228:233	arg1	showed					306:311	showed	306:311	showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+	306:398	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	7	46	theme	probe	1054:1058	arg1	application					1035:1045	the practical application	1021:1045	the practical application of the probe	1021:1058	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	6	47	contain	has	925:927	arg1	it					882:883	it	882:883	it	882:883	Moreover, it is highly resistant to interference and has a short response time, which can be rapidly responded within 1 min.					
37105254	6	47	contain	has	925:927	arg2	time					946:949	a short response time	929:949	a short response time	929:949	Moreover, it is highly resistant to interference and has a short response time, which can be rapidly responded within 1 min.					
37105254	8	48	theme	overall	1325:1331	arg1	properties					1357:1366	good overall physical and mechanical properties	1320:1366	good overall physical and mechanical properties	1320:1366	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	9	49	theme	further	1442:1448	arg1	expands					1450:1456	Au3+ and further expands	1433:1456	Au3+ and further expands the application field of agroforestry waste	1433:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	2	50	theme	fluorescence	315:326	arg1	emission					328:335	fluorescence emission	315:335	a fluorescence emission peak	313:340	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	0	51	theme	fluorescent	45:55	arg1	probe					57:61	Au3+ fluorescent probe	40:61	Au3+ fluorescent probe	40:61	Synthesis of corn bract cellulose-based Au3+ fluorescent probe and its application in composite membranes.					
37105254	9	52	theme	application	1462:1472	arg1	field					1474:1478	the application field	1458:1478	Au3+ and further expands the application field of agroforestry waste	1433:1500	This study provides a meaningful reference for the detection of Au3+ and further expands the application field of agroforestry waste.					
37105254	8	53	theme	good	1320:1323	arg1	properties					1357:1366	good overall physical and mechanical properties	1320:1366	good overall physical and mechanical properties	1320:1366	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	1	54	theme	real-time	118:126	arg1	monitoring					128:137	real-time monitoring	118:137	real-time monitoring of Au3+	118:145	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	7	55	theme	composite	1169:1177	arg1	film					1179:1182	the fluorescent composite film	1153:1182	the fluorescent composite film	1153:1182	In addition, to improve the practical application of the probe, the probe was prepared as a fluorescent composite film and the fluorescence effect shown by the fluorescent composite film is consistent with the fluorescence change of the probe MAC-1 itself.					
37105254	3	56	theme	Elemental	557:565	arg1	SEM					440:442	SEM	440:442	SEM (Sample microstructure images)	440:473	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	56	theme	Elemental	557:565	arg1	analysis					567:574	Elemental analysis	557:574	Elemental analysis	557:574	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	2	57	theme	DMF-H2O	267:273	arg1	solution					296:303	DMF-H2O (1:9, v/v, pH = 7.4) solution	267:303	solution	296:303	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	3	58	theme	1H	549:550	arg1	SEM					440:442	SEM	440:442	SEM (Sample microstructure images)	440:473	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	58	theme	1H	549:550	arg1	NMR					552:554	1H NMR	549:554	1H NMR	549:554	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	2	59	dep	solution	296:303	arg1	pH = 7.4					286:293	DMF-H2O (1:9, v/v, pH = 7.4) solution	267:303	pH = 7.4	286:293	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	2	59	dep	solution	296:303	arg1	v/v					281:283	DMF-H2O (1:9, v/v, pH = 7.4) solution	267:303	v/v	281:283	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	8	60	theme	fluorescent	1258:1268	arg1	film					1280:1283	The fluorescent composite film	1254:1283	The fluorescent composite film	1254:1283	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	2	61	with	520 nm	345:350	arg1	properties					380:389	quenching fluorescence properties	357:389	quenching fluorescence properties for Au3+	357:398	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	8	62	theme	physical	1333:1340	arg1	properties					1357:1366	good overall physical and mechanical properties	1320:1366	good overall physical and mechanical properties	1320:1366	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	3	63	theme	microstructure	452:465	arg1	images					467:472	Sample microstructure images	445:472	Sample microstructure images	445:472	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	63	theme	microstructure	452:465	arg1	SEM					440:442	SEM	440:442	SEM (Sample microstructure images)	440:473	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	64	theme	Sample	445:450	arg1	images					467:472	Sample microstructure images	445:472	Sample microstructure images	445:472	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	64	theme	Sample	445:450	arg1	SEM					440:442	SEM	440:442	SEM (Sample microstructure images)	440:473	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	8	65	contain	has	1290:1292	arg2	properties					1357:1366	good overall physical and mechanical properties	1320:1366	good overall physical and mechanical properties	1320:1366	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	8	65	contain	has	1290:1292	arg2	selectivity					1304:1314	excellent selectivity	1294:1314	excellent selectivity	1294:1314	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	8	65	contain	has	1290:1292	arg1	film					1280:1283	The fluorescent composite film	1254:1283	The fluorescent composite film	1254:1283	The fluorescent composite film also has excellent selectivity and good overall physical and mechanical properties.					
37105254	5	66	theme	Au3+	799:802	arg1	recognition					784:794	the recognition	780:794	the recognition of Au3+ by the probe MAC-1	780:821	The results showed that the recognition of Au3+ by the probe MAC-1 exhibited high selectivity and high sensitivity.					
37105254	1	67	theme	Au3+	142:145	arg1	monitoring					128:137	real-time monitoring	118:137	real-time monitoring of Au3+	118:145	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	1	68	theme	cellulose-based	161:175	arg1	probe					189:193	a corn bract cellulose-based fluorescent probe	148:193	a corn bract cellulose-based fluorescent probe MAC-1 for	148:203	To achieve real-time monitoring of Au3+, a corn bract cellulose-based fluorescent probe MAC-1 for was synthesized.					
37105254	2	69	theme	fluorescence	240:251	arg1	properties					253:262	good fluorescence properties	235:262	good fluorescence properties	235:262	MAC-1 showed good fluorescence properties in DMF-H2O (1:9, v/v, pH = 7.4) solution, showed a fluorescence emission peak at 520 nm with quenching fluorescence properties for Au3+.					
37105254	3	70	theme	X-ray	481:485	arg1	XRD					476:478	XRD	476:478	XRD (X-ray diffraction)	476:498	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
37105254	3	70	theme	X-ray	481:485	arg1	diffraction					487:497	X-ray diffraction	481:497	X-ray diffraction	481:497	The structure of MAC-1 was analyzed by SEM (Sample microstructure images), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), 1H NMR, Elemental analysis, EDS, Mapping and TG (Thermogravimetry) were analyzed.					
36535637	7	0	theme	hyaluronate	910:920	arg1	lyase					922:926	a hyaluronate lyase	908:926	a hyaluronate lyase	908:926	Oxidase activity was not detected, revealing that the enzyme is not an oxidase but a hyaluronate lyase.					
36535637	0	1	theme	Haliscomenobacter	77:93	arg1	hydrossis					95:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	5	2	theme	[2Fe-2S	687:693	arg1	subunits					704:711	molybdopterin-binding and [2Fe-2S]-binding subunits	661:711	molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein	661:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	2	theme	[2Fe-2S	687:693	arg1	subunits					648:655	the subunits	644:655	the subunits	644:655	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	1	3	from	sludge	181:186	arg1	common					161:166	common	161:166	common	161:166	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	4	4	theme	filtration	499:508	arg1	chromatography					510:523	gel filtration chromatography	495:523	gel filtration chromatography	495:523	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	9	5	theme	first	1178:1182	arg1	enzyme					1164:1169	the enzyme	1160:1169	the enzyme	1160:1169	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	9	5	theme	first	1178:1182	arg1	lyase					1210:1214	the first heterodimeric hyaluronate lyase	1174:1214	the first heterodimeric hyaluronate lyase	1174:1214	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	5	6	theme	-binding	695:702	arg1	subunits					704:711	molybdopterin-binding and [2Fe-2S]-binding subunits	661:711	molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein	661:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	6	theme	-binding	695:702	arg1	subunits					648:655	the subunits	644:655	the subunits	644:655	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	8	7	theme	hyaluronic	1021:1030	arg1	acid					1032:1035	hyaluronic acid	1021:1035	hyaluronic acid	1021:1035	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	3	8	located	found	340:344	arg1	genome					353:358	the genome	349:358	the genome	349:358	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	3	8	located	found	340:344	arg2	gene					331:334	no hyaluronate lyase gene	310:334	no hyaluronate lyase gene	310:334	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	4	9	from	peak	487:490	arg1	SDS-PAGE					465:472	SDS-PAGE	465:472	SDS-PAGE	465:472	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	4	9	from	peak	487:490	arg1	chromatography					510:523	gel filtration chromatography	495:523	gel filtration chromatography	495:523	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	6	10	theme	cofactors	771:779	arg1	presence					755:762	The presence	751:762	The presence of the cofactors	751:779	The presence of the cofactors was confirmed using spectrometric analysis.					
36535637	8	11	theme	3-	1040:1041	arg1	-N-acetyl-d-glucosamine					1073:1095	3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine	1040:1095	3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine	1040:1095	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	5	12	theme	acid	583:586	arg1	sequence					588:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	0	13	theme	heterodimeric	2:14	arg1	lyase					28:32	A heterodimeric hyaluronate lyase	0:32	A heterodimeric hyaluronate lyase	0:32	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	4	14	theme	single	480:485	arg1	peak					487:490	a single peak	478:490	a single peak on gel filtration chromatography	478:523	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	1	15	from	common	161:166	arg1	sludge					181:186	activated sludge	171:186	activated sludge	171:186	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	9	16	theme	hyaluronate	1101:1111	arg1	EC					1121:1122	EC 4.2.2.1	1121:1130	EC 4.2.2.1	1121:1130	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	9	16	theme	hyaluronate	1101:1111	arg1	lyases					1113:1118	hyaluronate lyases	1101:1118	hyaluronate lyases (EC 4.2.2.1)	1101:1131	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	5	17	theme	protein	742:748	arg1	subunits					704:711	molybdopterin-binding and [2Fe-2S]-binding subunits	661:711	molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein	661:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	17	theme	protein	742:748	arg1	subunits					648:655	the subunits	644:655	the subunits	644:655	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	18	theme	molybdopterin-binding	661:681	arg1	subunits					704:711	molybdopterin-binding and [2Fe-2S]-binding subunits	661:711	molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein	661:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	18	theme	molybdopterin-binding	661:681	arg1	subunits					648:655	the subunits	644:655	the subunits	644:655	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	1	19	theme	Haliscomenobacter	106:122	arg1	bacterium					151:159	a filamentous bacterium	137:159	a filamentous bacterium common in activated sludge	137:186	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	1	19	theme	Haliscomenobacter	106:122	arg1	hydrossis					124:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	5	20	theme	oxidase	727:733	arg1	protein					742:748	a xanthine oxidase family protein	716:748	a xanthine oxidase family protein	716:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	21	theme	mass	601:604	arg1	analyses					620:627	mass spectrometric analyses	601:627	mass spectrometric analyses	601:627	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	5	22	theme	spectrometric	606:618	arg1	analyses					620:627	mass spectrometric analyses	601:627	mass spectrometric analyses	601:627	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	0	23	theme	hyaluronate	16:26	arg1	lyase					28:32	A heterodimeric hyaluronate lyase	0:32	A heterodimeric hyaluronate lyase	0:32	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	5	24	theme	family	735:740	arg1	protein					742:748	a xanthine oxidase family protein	716:748	a xanthine oxidase family protein	716:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	8	25	theme	magnetic	937:944	arg1	resonance					946:954	Nuclear magnetic resonance	929:954	Nuclear magnetic resonance analysis of the enzymatic digest	929:987	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	4	26	from	bands	456:460	arg1	SDS-PAGE					465:472	SDS-PAGE	465:472	SDS-PAGE	465:472	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	4	26	from	bands	456:460	arg1	chromatography					510:523	gel filtration chromatography	495:523	gel filtration chromatography	495:523	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	2	27	theme	lyase	257:261	arg1	activity					263:270	hyaluronate lyase activity	245:270	hyaluronate lyase activity	245:270	The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected in its culture.					
36535637	8	28	theme	Nuclear	929:935	arg1	resonance					946:954	Nuclear magnetic resonance	929:954	Nuclear magnetic resonance analysis of the enzymatic digest	929:987	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	2	29	theme	hyaluronate	245:255	arg1	activity					263:270	hyaluronate lyase activity	245:270	hyaluronate lyase activity	245:270	The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected in its culture.					
36535637	9	30	theme	heterodimeric	1184:1196	arg1	enzyme					1164:1169	the enzyme	1160:1169	the enzyme	1160:1169	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	9	30	theme	heterodimeric	1184:1196	arg1	lyase					1210:1214	the first heterodimeric hyaluronate lyase	1174:1214	the first heterodimeric hyaluronate lyase	1174:1214	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	3	31	theme	novel	397:401	arg1	lyase					415:419	a novel hyaluronate lyase	395:419	a novel hyaluronate lyase	395:419	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	7	32	theme	Oxidase	825:831	arg1	activity					833:840	Oxidase activity	825:840	Oxidase activity	825:840	Oxidase activity was not detected, revealing that the enzyme is not an oxidase but a hyaluronate lyase.					
36535637	3	33	theme	hyaluronate	313:323	arg1	gene					331:334	no hyaluronate lyase gene	310:334	no hyaluronate lyase gene	310:334	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	0	34	theme	sludge	60:65	arg1	hydrossis					95:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	8	35	theme	resonance	946:954	arg1	analysis					956:963	Nuclear magnetic resonance analysis	929:963	Nuclear magnetic resonance analysis of the enzymatic digest	929:987	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	3	36	theme	hyaluronate	403:413	arg1	lyase					415:419	a novel hyaluronate lyase	395:419	a novel hyaluronate lyase	395:419	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	4	37	theme	heterodimeric	539:551	arg1	composition					553:563	a heterodimeric composition	537:563	a heterodimeric composition	537:563	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	3	38	theme	lyase	325:329	arg1	gene					331:334	no hyaluronate lyase gene	310:334	no hyaluronate lyase gene	310:334	However, no hyaluronate lyase gene was found in the genome, suggesting the bacterium secretes a novel hyaluronate lyase.					
36535637	4	39	theme	purified	426:433	arg1	enzyme					435:440	The purified enzyme	422:440	The purified enzyme	422:440	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	5	40	theme	N-terminal	566:575	arg1	sequence					588:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	1	41	theme	filamentous	139:149	arg1	bacterium					151:159	a filamentous bacterium	137:159	a filamentous bacterium common in activated sludge	137:186	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	1	41	theme	filamentous	139:149	arg1	hydrossis					124:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	6	42	theme	spectrometric	801:813	arg1	analysis					815:822	spectrometric analysis	801:822	spectrometric analysis	801:822	The presence of the cofactors was confirmed using spectrometric analysis.					
36535637	2	43	theme	hyaluronic	224:233	arg1	acid					235:238	hyaluronic acid	224:238	hyaluronic acid	224:238	The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected in its culture.					
36535637	5	44	theme	amino	577:581	arg1	sequence					588:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence	566:595	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	2	45	located	detected	276:283	arg1	culture					292:298	its culture	288:298	its culture	288:298	The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected in its culture.					
36535637	2	45	located	detected	276:283	arg2	activity					263:270	hyaluronate lyase activity	245:270	hyaluronate lyase activity	245:270	The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected in its culture.					
36535637	5	46	theme	xanthine	718:725	arg1	oxidase					727:733	xanthine oxidase	718:733	a xanthine oxidase family protein	716:748	N-terminal amino acid sequence and mass spectrometric analyses suggested that the subunits are molybdopterin-binding and [2Fe-2S]-binding subunits of a xanthine oxidase family protein.					
36535637	8	47	theme	digest	982:987	arg1	analysis					956:963	Nuclear magnetic resonance analysis	929:963	Nuclear magnetic resonance analysis of the enzymatic digest	929:987	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	1	48	theme	common	161:166	arg1	bacterium					151:159	a filamentous bacterium	137:159	a filamentous bacterium common in activated sludge	137:186	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	1	48	theme	common	161:166	arg1	hydrossis					124:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis	106:132	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36535637	0	49	theme	bacterium	67:75	arg1	hydrossis					95:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	8	50	theme	enzymatic	972:980	arg1	digest					982:987	the enzymatic digest	968:987	the enzymatic digest	968:987	Nuclear magnetic resonance analysis of the enzymatic digest revealed that the enzyme breaks hyaluronic acid to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl-d-glucosamine.					
36535637	0	51	theme	activated	50:58	arg1	hydrossis					95:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	the activated sludge bacterium Haliscomenobacter hydrossis	46:103	A heterodimeric hyaluronate lyase secreted by the activated sludge bacterium Haliscomenobacter hydrossis.					
36535637	4	52	theme	gel	495:497	arg1	chromatography					510:523	gel filtration chromatography	495:523	gel filtration chromatography	495:523	The purified enzyme exhibited two bands on SDS-PAGE and a single peak on gel filtration chromatography, suggesting a heterodimeric composition.					
36535637	9	53	theme	hyaluronate	1198:1208	arg1	enzyme					1164:1169	the enzyme	1160:1169	the enzyme	1160:1169	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	9	53	theme	hyaluronate	1198:1208	arg1	lyase					1210:1214	the first heterodimeric hyaluronate lyase	1174:1214	the first heterodimeric hyaluronate lyase	1174:1214	As hyaluronate lyases (EC 4.2.2.1) are monomeric or trimeric, the enzyme is the first heterodimeric hyaluronate lyase.					
36535637	1	54	theme	activated	171:179	arg1	sludge					181:186	activated sludge	171:186	activated sludge	171:186	Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge.					
36493663	1	0	theme	conditions	351:360	arg1	compositions					388:399	biomass compositions	380:399	biomass compositions	380:399	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	0	theme	conditions	351:360	arg1	complexity					366:375	complexity	366:375	complexity of biomass compositions	366:399	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	0	theme	conditions	351:360	arg1	variety					330:336	the variety	326:336	the variety of operating conditions	326:360	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	0	theme	conditions	351:360	arg1	conditions					351:360	operating conditions	341:360	operating conditions	341:360	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	3	1	from	content	737:743	arg1	feedstocks					811:820	the LB feedstocks	804:820	the LB feedstocks	804:820	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	7	2	with	positive	1326:1333	arg1	variations					1377:1386	large variations	1371:1386	large variations for different inorganics	1371:1411	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	2	3	theme	polyvinyl	492:500	arg1	PVC					512:514	PVC	512:514	PVC	512:514	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	2	3	theme	polyvinyl	492:500	arg1	chloride					502:509	polyvinyl chloride	492:509	polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions	492:604	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	3	4	theme	-20.3 	675:680	arg1	%					681:681	%	681:681	%	681:681	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	2	5	theme	fundamental	581:591	arg1	interactions					593:604	the fundamental interactions	577:604	the fundamental interactions	577:604	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	6	6	theme	polymeric	1110:1118	arg1	hydrochar					1120:1128	polymeric hydrochar	1110:1128	polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1110:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	2	7	theme	mass	524:527	arg1	ratio					529:533	the mass ratio	520:533	the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions	520:604	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	7	8	theme	154 	1359:1362	arg1	%					1354:1354	%	1354:1354	%	1354:1354	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	3	9	from	composition	749:759	arg1	feedstocks					811:820	the LB feedstocks	804:820	the LB feedstocks	804:820	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	9	10	theme	process	1623:1629	arg1	water					1631:1635	the process water	1619:1635	the process water	1619:1635	Soluble inorganics were dissolved in the process water by HCl leaching.					
36493663	7	11	theme	different	1392:1400	arg1	inorganics					1402:1411	different inorganics	1392:1411	different inorganics	1392:1411	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	3	12	dep	content	737:743	arg1	the					733:735	the	733:735	the	733:735	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	7	13	theme	inorganics	1430:1439	arg1	contents					1441:1448	inorganics contents	1430:1448	inorganics contents in LB	1430:1454	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	5	14	theme	PVC	962:964	arg1	aggregation					966:976	PVC aggregation	962:976	PVC aggregation	962:976	The LB fragments prevented PVC aggregation while promoted PVC fragmentation, thereby facilitating dechlorination.					
36493663	1	15	theme	interaction	282:292	arg1	unclear					309:315	unclear	309:315	unclear	309:315	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	15	theme	interaction	282:292	arg1	mechanisms					294:303	the interaction mechanisms	278:303	the interaction mechanisms	278:303	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	6	16	attach	derived	1076:1082	arg2	inhibitors					1261:1270	significant dechlorination inhibitors	1234:1270	significant dechlorination inhibitors	1234:1270	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	16	attach	derived	1076:1082	arg1	lignin					1099:1104	insoluble lignin	1089:1104	insoluble lignin	1089:1104	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	16	attach	derived	1076:1082	arg1	hydrochar					1120:1128	polymeric hydrochar	1110:1128	polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1110:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	16	attach	derived	1076:1082	arg2	hydrochar					1066:1074	The polyaromatic hydrochar	1049:1074	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1049:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	1	17	theme	biomass	380:386	arg1	compositions					388:399	biomass compositions	380:399	biomass compositions	380:399	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	7	18	dep	%	1354:1354	arg1	to					1356:1357	to	1356:1357	to	1356:1357	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	6	19	theme	insoluble	1089:1097	arg1	lignin					1099:1104	insoluble lignin	1089:1104	insoluble lignin	1089:1104	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	3	20	theme	lignin	794:799	arg1	composition					749:759	composition	749:759	composition	749:759	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	3	20	theme	lignin	794:799	arg1	content					737:743	content	737:743	content	737:743	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	1	21	theme	compositions	388:399	arg1	compositions					388:399	biomass compositions	380:399	biomass compositions	380:399	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	21	theme	compositions	388:399	arg1	complexity					366:375	complexity	366:375	complexity of biomass compositions	366:399	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	21	theme	compositions	388:399	arg1	variety					330:336	the variety	326:336	the variety of operating conditions	326:360	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	21	theme	compositions	388:399	arg1	conditions					351:360	operating conditions	341:360	operating conditions	341:360	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	2	22	theme	wheat	441:445	arg1	straw					447:451	wheat straw	441:451	wheat straw	441:451	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	7	23	theme	0.74 	1349:1353	arg1	%					1354:1354	%	1354:1354	%	1354:1354	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	4	24	theme	Hydroxyl	823:830	arg1	groups					843:848	Hydroxyl functional groups	823:848	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates	823:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	5	25	theme	LB	939:940	arg1	fragments					942:950	The LB fragments	935:950	The LB fragments	935:950	The LB fragments prevented PVC aggregation while promoted PVC fragmentation, thereby facilitating dechlorination.					
36493663	8	26	theme	inorganics	1532:1541	arg1	amount					1493:1498	A large amount	1485:1498	A large amount of water-insoluble/acid-soluble inorganics	1485:1541	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	8	26	theme	inorganics	1532:1541	arg1	inorganics					1532:1541	water-insoluble/acid-soluble inorganics	1503:1541	water-insoluble/acid-soluble inorganics	1503:1541	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	1	27	theme	chlorinated	192:202	arg1	waste					204:208	chlorinated waste	192:208	chlorinated waste	192:208	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	0	28	theme	Co-hydrothermal	0:14	arg1	carbonization					16:28	Co-hydrothermal carbonization	0:28	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose	0:69	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose biomasses for chlorine and inorganics removal.					
36493663	8	29	theme	metathesis	1561:1570	arg1	reaction					1572:1579	a metathesis reaction	1559:1579	a metathesis reaction	1559:1579	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	9	30	theme	HCl	1640:1642	arg1	leaching					1644:1651	HCl leaching	1640:1651	HCl leaching	1640:1651	Soluble inorganics were dissolved in the process water by HCl leaching.					
36493663	1	31	theme	waste	204:208	arg1	co-HTC					149:154	co-HTC	149:154	co-HTC	149:154	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	31	theme	waste	204:208	arg1	carbonization					134:146	Co-hydrothermal carbonization	118:146	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste	118:208	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	0	32	theme	polyvinyl	33:41	arg1	chloride					43:50	polyvinyl chloride	33:50	polyvinyl chloride	33:50	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose biomasses for chlorine and inorganics removal.					
36493663	3	33	dep	%	681:681	arg1	to					683:684	to	683:684	to	683:684	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	1	34	theme	Co-hydrothermal	118:132	arg1	co-HTC					149:154	co-HTC	149:154	co-HTC	149:154	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	34	theme	Co-hydrothermal	118:132	arg1	carbonization					134:146	Co-hydrothermal carbonization	118:146	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste	118:208	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	2	35	theme	9:1	538:540	arg1	ratio					529:533	the mass ratio	520:533	the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions	520:604	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	6	36	attach	derived	1130:1136	arg1	lignin					1181:1186	soluble lignin	1173:1186	soluble lignin	1173:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	36	attach	derived	1130:1136	arg1	cellulose					1158:1166	cellulose	1158:1166	cellulose	1158:1166	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	36	attach	derived	1130:1136	arg1	hemicellulose					1143:1155	hemicellulose	1143:1155	hemicellulose	1143:1155	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	36	attach	derived	1130:1136	arg2	hydrochar					1120:1128	polymeric hydrochar	1110:1128	polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1110:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	2	37	theme	corn	425:428	arg1	stalk					430:434	corn stalk	425:434	corn stalk	425:434	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	7	38	theme	inorganics	1305:1314	arg1	efficiency					1291:1300	removal efficiency	1283:1300	removal efficiency of inorganics (RE)	1283:1319	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	6	39	theme	polyaromatic	1053:1064	arg1	hydrochar					1066:1074	The polyaromatic hydrochar	1049:1074	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1049:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	39	theme	polyaromatic	1053:1064	arg1	inhibitors					1261:1270	significant dechlorination inhibitors	1234:1270	significant dechlorination inhibitors	1234:1270	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	0	40	theme	chloride	43:50	arg1	carbonization					16:28	Co-hydrothermal carbonization	0:28	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose	0:69	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose biomasses for chlorine and inorganics removal.					
36493663	4	41	theme	PVC	917:919	arg1	substitution					921:932	PVC substitution	917:932	PVC substitution	917:932	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	6	42	theme	dechlorination	1246:1259	arg1	hydrochar					1066:1074	The polyaromatic hydrochar	1049:1074	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1049:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	42	theme	dechlorination	1246:1259	arg1	inhibitors					1261:1270	significant dechlorination inhibitors	1234:1270	significant dechlorination inhibitors	1234:1270	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	4	43	theme	functional	832:841	arg1	groups					843:848	Hydroxyl functional groups	823:848	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates	823:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	1	44	theme	organic	236:242	arg1	chlorine					244:251	organic chlorine	236:251	organic chlorine	236:251	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	9	45	theme	Soluble	1582:1588	arg1	inorganics					1590:1599	Soluble inorganics	1582:1599	Soluble inorganics	1582:1599	Soluble inorganics were dissolved in the process water by HCl leaching.					
36493663	4	46	theme	soluble	867:873	arg1	intermediates					894:906	cellulose and soluble lignin dehydration intermediates	853:906	cellulose and soluble lignin dehydration intermediates	853:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	6	47	theme	significant	1234:1244	arg1	hydrochar					1066:1074	The polyaromatic hydrochar	1049:1074	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin	1049:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	6	47	theme	significant	1234:1244	arg1	inhibitors					1261:1270	significant dechlorination inhibitors	1234:1270	significant dechlorination inhibitors	1234:1270	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	4	48	from	groups	843:848	arg1	intermediates					894:906	cellulose and soluble lignin dehydration intermediates	853:906	cellulose and soluble lignin dehydration intermediates	853:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	0	49	theme	lignocellulose	56:69	arg1	carbonization					16:28	Co-hydrothermal carbonization	0:28	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose	0:69	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose biomasses for chlorine and inorganics removal.					
36493663	6	50	theme	soluble	1173:1179	arg1	lignin					1181:1186	soluble lignin	1173:1186	soluble lignin	1173:1186	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	4	51	theme	cellulose	853:861	arg1	intermediates					894:906	cellulose and soluble lignin dehydration intermediates	853:906	cellulose and soluble lignin dehydration intermediates	853:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	7	52	from	contents	1441:1448	arg1	LB					1453:1454	LB	1453:1454	LB	1453:1454	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	4	53	theme	dehydration	882:892	arg1	intermediates					894:906	cellulose and soluble lignin dehydration intermediates	853:906	cellulose and soluble lignin dehydration intermediates	853:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	3	54	theme	synergistic	611:621	arg1	SI					630:631	SI	630:631	SI	630:631	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	3	54	theme	synergistic	611:621	arg1	index					623:627	The synergistic index	607:627	The synergistic index (SI) of dechlorination efficiency	607:661	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	7	55	theme	large	1371:1375	arg1	variations					1377:1386	large variations	1371:1386	large variations for different inorganics	1371:1411	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	7	56	theme	removal	1283:1289	arg1	efficiency					1291:1300	removal efficiency	1283:1300	removal efficiency of inorganics (RE)	1283:1319	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	0	57	dep	chlorine	85:92	arg1	removal					109:115	removal	109:115	removal	109:115	Co-hydrothermal carbonization of polyvinyl chloride and lignocellulose biomasses for chlorine and inorganics removal.					
36493663	3	58	theme	hemicellulose	775:787	arg1	composition					749:759	composition	749:759	composition	749:759	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	3	58	theme	hemicellulose	775:787	arg1	content					737:743	content	737:743	content	737:743	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	4	59	theme	lignin	875:880	arg1	intermediates					894:906	cellulose and soluble lignin dehydration intermediates	853:906	cellulose and soluble lignin dehydration intermediates	853:906	Hydroxyl functional groups in cellulose and soluble lignin dehydration intermediates promoted PVC substitution.					
36493663	3	60	theme	dechlorination	637:650	arg1	efficiency					652:661	dechlorination efficiency	637:661	dechlorination efficiency	637:661	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	5	61	theme	PVC	993:995	arg1	fragmentation					997:1009	PVC fragmentation	993:1009	PVC fragmentation	993:1009	The LB fragments prevented PVC aggregation while promoted PVC fragmentation, thereby facilitating dechlorination.					
36493663	8	62	theme	large	1487:1491	arg1	amount					1493:1498	A large amount	1485:1498	A large amount of water-insoluble/acid-soluble inorganics	1485:1541	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	8	62	theme	large	1487:1491	arg1	inorganics					1532:1541	water-insoluble/acid-soluble inorganics	1503:1541	water-insoluble/acid-soluble inorganics	1503:1541	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	7	63	theme	efficiency	1291:1300	arg1	SI					1277:1278	All SI	1273:1278	All SI of removal efficiency of inorganics (RE)	1273:1319	All SI of removal efficiency of inorganics (RE) were positive, ranging from 0.74 % to 154 %, with large variations for different inorganics, indicating that inorganics contents in LB influenced RE significantly.					
36493663	3	64	theme	LB	808:809	arg1	feedstocks					811:820	the LB feedstocks	804:820	the LB feedstocks	804:820	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	2	65	from	ratio	529:533	arg1	PVC					512:514	PVC	512:514	PVC	512:514	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	2	65	from	ratio	529:533	arg1	chloride					502:509	polyvinyl chloride	492:509	polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions	492:604	Pine, bamboo, corncob, corn stalk, and wheat straw were co-hydrothermally carbonized with polyvinyl chloride (PVC) at the mass ratio of 9:1 for 30 min under 260 °C to explore the fundamental interactions.					
36493663	8	66	theme	water-insoluble/acid-soluble	1503:1530	arg1	inorganics					1532:1541	water-insoluble/acid-soluble inorganics	1503:1541	water-insoluble/acid-soluble inorganics	1503:1541	A large amount of water-insoluble/acid-soluble inorganics was removed via a metathesis reaction.					
36493663	3	67	theme	efficiency	652:661	arg1	SI					630:631	SI	630:631	SI	630:631	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	3	67	theme	efficiency	652:661	arg1	index					623:627	The synergistic index	607:627	The synergistic index (SI) of dechlorination efficiency	607:661	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	6	68	theme	PVC	1219:1221	arg1	surface					1201:1207	the surface	1197:1207	the surface of molten PVC	1197:1221	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	1	69	theme	lignocellulose	160:173	arg1	biomass					175:181	lignocellulose biomass	160:181	lignocellulose biomass (LB)	160:186	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	69	theme	lignocellulose	160:173	arg1	LB					184:185	LB	184:185	LB	184:185	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	3	70	theme	cellulose	764:772	arg1	composition					749:759	composition	749:759	composition	749:759	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	3	70	theme	cellulose	764:772	arg1	content					737:743	content	737:743	content	737:743	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	1	71	theme	operating	341:349	arg1	conditions					351:360	operating conditions	341:360	operating conditions	341:360	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	6	72	theme	molten	1212:1217	arg1	PVC					1219:1221	molten PVC	1212:1221	molten PVC	1212:1221	The polyaromatic hydrochar derived from insoluble lignin and polymeric hydrochar derived from hemicellulose, cellulose, and soluble lignin can coat the surface of molten PVC and act as significant dechlorination inhibitors.					
36493663	3	73	theme	19.9 	686:690	arg1	%					681:681	%	681:681	%	681:681	The synergistic index (SI) of dechlorination efficiency ranged from -20.3 % to 19.9 %, indicating the interaction depended on the content and composition of cellulose, hemicellulose, and lignin in the LB feedstocks.					
36493663	1	74	theme	biomass	175:181	arg1	co-HTC					149:154	co-HTC	149:154	co-HTC	149:154	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36493663	1	74	theme	biomass	175:181	arg1	carbonization					134:146	Co-hydrothermal carbonization	118:146	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste	118:208	Co-hydrothermal carbonization (co-HTC) of lignocellulose biomass (LB) and chlorinated waste can simultaneously remove organic chlorine and inorganics, however, the interaction mechanisms are unclear owing to the variety of operating conditions and complexity of biomass compositions.					
36565629	4	0	theme	birds	523:527	arg1	cages					512:516	8 replicate cages	500:516	8 replicate cages of 7 birds each	500:532	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	20	1	theme	3	1820:1820	arg1	%					1821:1821	%	1821:1821	%	1821:1821	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	2	2	from	effects	169:175	arg1	nutrient					207:214	nutrient	207:214	nutrient	207:214	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	2	2	from	effects	169:175	arg1	utilization					227:237	energy utilization	220:237	energy utilization	220:237	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	6	3	dep	waxy	668:671	arg1	carbohydrases					704:716	 × 4 carbohydrases	699:716	 × 4 carbohydrases	699:716	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	20	4	theme	%	1809:1809	arg1	AMEn					1811:1814	2.5% AMEn	1806:1814	2.5% AMEn	1806:1814	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	15	5	theme	Tukey	1278:1282	arg1	test					1284:1287	Tukey test	1278:1287	Tukey test (P ≤ 0.05)	1278:1298	Data were subjected to analysis of variance and means were compared by Tukey test (P ≤ 0.05).					
36565629	15	5	theme	Tukey	1278:1282	arg1	≤					1292:1292	P ≤ 0.05	1290:1297	P ≤ 0.05	1290:1297	Data were subjected to analysis of variance and means were compared by Tukey test (P ≤ 0.05).					
36565629	17	6	dep	non-supplemented	1515:1530	arg1	feeds					1532:1536	feeds	1532:1536	feeds	1532:1536	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	6	7	theme	 × 4	699:702	arg1	carbohydrases					704:716	 × 4 carbohydrases	699:716	 × 4 carbohydrases	699:716	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	17	8	from	increases	1445:1453	arg1	AME					1464:1466	AME	1464:1466	AME	1464:1466	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	17	8	from	increases	1445:1453	arg1	digestibility					1480:1492	N digestibility	1478:1492	N digestibility	1478:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	14	9	theme	starch	1162:1167	arg1	digestibility					1169:1181	2, jejunal starch digestibility	1151:1181	digestibility	1169:1181	2, jejunal starch digestibility was determined on d 24.					
36565629	4	10	from	North	434:438	arg1	located					419:425	located	419:425	located	419:425	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	9	11	dep	complex	894:900	arg1	glucanase					914:922	glucanase	914:922	glucanase	914:922	1, α-amylase, β-xylanase, or carbohydrase complex (cellulase, glucanase, and xylanase) were added to the diet.					
36565629	9	11	dep	complex	894:900	arg1	xylanase					929:936	xylanase	929:936	xylanase	929:936	1, α-amylase, β-xylanase, or carbohydrase complex (cellulase, glucanase, and xylanase) were added to the diet.					
36565629	9	11	dep	complex	894:900	arg1	cellulase					903:911	cellulase	903:911	cellulase	903:911	1, α-amylase, β-xylanase, or carbohydrase complex (cellulase, glucanase, and xylanase) were added to the diet.					
36565629	19	12	theme	highest	1699:1705	arg1	digestibility					1707:1719	the highest digestibility	1695:1719	the highest digestibility of N and starch	1695:1735	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	4	13	theme	chicks	328:333	arg1	total					301:305	a total	299:305	a total of 448 Cobb 500 male chicks	299:333	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	16	14	contain	had	1328:1330	arg1	Corn					1301:1304	Corn	1301:1304	Corn from the North origin	1301:1326	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	16	14	contain	had	1328:1330	arg2	higher					1332:1337	higher	1332:1337	higher	1332:1337	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	16	14	contain	had	1328:1330	arg2	digestibility					1354:1366	digestibility	1354:1366	digestibility	1354:1366	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	16	14	contain	had	1328:1330	arg2	AMEn					1344:1347	AMEn	1344:1347	AMEn	1344:1347	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	16	15	from	origin	1321:1326	arg1	Corn					1301:1304	Corn	1301:1304	Corn from the North origin	1301:1326	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	4	16	dep	birds	523:527	arg1	each					529:532	each	529:532	each	529:532	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	12	17	theme	AME	1107:1109	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	2	18	theme	carbohydrases	190:202	arg1	effects					169:175	the effects	165:175	the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers	165:285	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	20	19	theme	Corn	1738:1741	arg1	diets					1743:1747	Corn diets	1738:1747	Corn diets supplemented with amylase + xylanase	1738:1784	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	4	20	theme	factorial	363:371	arg1	arrangement					373:383	a 2 × 4 factorial arrangement	355:383	a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation)	355:492	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	7	21	from	corn	806:809	arg1	studies					835:841	both studies	830:841	both studies	830:841	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	12	22	theme	P	1094:1094	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	7	23	from	d	816:816	arg1	corn					806:809	95.9% corn	800:809	95.9% corn from d 14 to 24 in both studies	800:841	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	6	24	theme	male	559:562	arg1	chicks					564:569	2, 672 Cobb 500 male chicks	543:569	2, 672 Cobb 500 male chicks	543:569	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	19	25	theme	EE	1587:1588	arg1	2					1558:1558	2	1558:1558	2	1558:1558	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	25	theme	EE	1587:1588	arg1	digestibility					1590:1602	EE digestibility	1587:1602	EE digestibility	1587:1602	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	2	26	theme	energy	220:225	arg1	utilization					227:237	energy utilization	220:237	energy utilization	220:237	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	17	27	theme	%	1473:1473	arg1	increases					1445:1453	increases	1445:1453	increases of 3% in AME and 2% in N digestibility	1445:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	4	28	from	South	443:447	arg1	located					419:425	located	419:425	located	419:425	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	4	29	theme	Brazil × 4	452:461	arg1	supplementation					477:491	Brazil × 4 carbohydrases supplementation	452:491	Brazil × 4 carbohydrases supplementation	452:491	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	16	30	theme	North	1315:1319	arg1	origin					1321:1326	the North origin	1311:1326	the North origin	1311:1326	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	17	31	theme	N	1478:1478	arg1	digestibility					1480:1492	N digestibility	1478:1492	N digestibility	1478:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	6	32	theme	3 × 4	608:612	arg1	arrangement					624:634	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	20	33	theme	starch	1823:1828	arg1	digestibility					1830:1842	3% starch digestibility	1820:1842	3% starch digestibility	1820:1842	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	0	34	theme	Research	0:7	arg1	Note					9:12	Research Note	0:12	Research Note	0:12	Research Note: Corn energy and nutrient utilization by broilers as affected by geographic areas and carbohydrases.					
36565629	16	35	theme	≤	1405:1405	arg1	P					1403:1403	P ≤ 0.05	1403:1410	P ≤ 0.05	1403:1410	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	16	35	theme	≤	1405:1405	arg1	South					1396:1400	the South	1392:1400	the South (P ≤ 0.05)	1392:1411	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	7	36	theme	95.9	800:803	arg1	%					804:804	%	804:804	%	804:804	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	17	37	from	digestibility	1480:1492	arg1	increases					1445:1453	increases	1445:1453	increases of 3% in AME and 2% in N digestibility	1445:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	6	38	theme	birds	748:752	arg1	cages					737:741	8 replicate cages	725:741	8 replicate cages of 7 birds	725:752	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	12	39	theme	N	1063:1063	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	12	40	theme	ether	1066:1070	arg1	EE					1081:1082	EE	1081:1082	EE	1081:1082	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	12	40	theme	ether	1066:1070	arg1	extract					1072:1078	ether extract	1066:1078	ether extract (EE)	1066:1083	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	4	41	theme	supplementation	477:491	arg1	North					434:438	the North	430:438	the North	430:438	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	4	41	theme	supplementation	477:491	arg1	South					443:447	South	443:447	South	443:447	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	0	42	theme	nutrient	31:38	arg1	utilization					40:50	nutrient utilization	31:50	nutrient utilization by broilers	31:62	Research Note: Corn energy and nutrient utilization by broilers as affected by geographic areas and carbohydrases.					
36565629	4	43	theme	Cobb	314:317	arg1	chicks					328:333	448 Cobb 500 male chicks	310:333	448 Cobb 500 male chicks	310:333	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	17	44	from	AME	1464:1466	arg1	increases					1445:1453	increases	1445:1453	increases of 3% in AME and 2% in N digestibility	1445:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	12	45	theme	DM	1059:1060	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	6	46	theme	corn	639:642	arg1	semi-dent					674:682	semi-dent	674:682	semi-dent	674:682	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	46	theme	corn	639:642	arg1	semi-flint					688:697	semi-flint	688:697	semi-flint	688:697	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	46	theme	corn	639:642	arg1	waxy					668:671	waxy	668:671	waxy	668:671	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	46	theme	corn	639:642	arg1	compositions					654:665	[3 corn endosperm compositions	636:665	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	7	47	theme	test	784:787	arg1	diets					789:793	semi-purified test diets	770:793	semi-purified test diets	770:793	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	17	48	from	%	1459:1459	arg1	AME					1464:1466	AME	1464:1466	AME	1464:1466	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	17	48	from	%	1459:1459	arg1	digestibility					1480:1492	N digestibility	1478:1492	N digestibility	1478:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	19	49	theme	highest	1565:1571	arg1	values					1576:1581	the highest ME values	1561:1581	the highest ME values	1561:1581	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	49	theme	highest	1565:1571	arg1	2					1558:1558	2	1558:1558	2	1558:1558	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	6	50	dep	cages	737:741	arg1	replicate					727:735	replicate	727:735	replicate	727:735	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	20	51	theme	%	1821:1821	arg1	digestibility					1830:1842	3% starch digestibility	1820:1842	3% starch digestibility	1820:1842	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	15	52	theme	P	1290:1290	arg1	test					1284:1287	Tukey test	1278:1287	Tukey test (P ≤ 0.05)	1278:1298	Data were subjected to analysis of variance and means were compared by Tukey test (P ≤ 0.05).					
36565629	15	52	theme	P	1290:1290	arg1	≤					1292:1292	P ≤ 0.05	1290:1297	P ≤ 0.05	1290:1297	Data were subjected to analysis of variance and means were compared by Tukey test (P ≤ 0.05).					
36565629	22	53	theme	endosperm	1985:1993	arg1	composition					1995:2005	the endosperm composition	1981:2005	the endosperm composition	1981:2005	Corn genetics, expressed by the endosperm composition, and carbohydrase supplementation influenced energy and nutrient utilization by broilers.					
36565629	20	54	theme	digestibility	1830:1842	arg1	improvements					1790:1801	improvements	1790:1801	improvements of 2.5% AMEn and 3% starch digestibility	1790:1842	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	22	55	theme	carbohydrase	2012:2023	arg1	supplementation					2025:2039	carbohydrase supplementation	2012:2039	carbohydrase supplementation	2012:2039	Corn genetics, expressed by the endosperm composition, and carbohydrase supplementation influenced energy and nutrient utilization by broilers.					
36565629	4	56	theme	2 × 4	357:361	arg1	arrangement					373:383	a 2 × 4 factorial arrangement	355:383	a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation)	355:492	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	2	57	theme	different	252:260	arg1	compositions					262:273	different compositions	252:273	different compositions	252:273	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	4	58	theme	male	323:326	arg1	chicks					328:333	448 Cobb 500 male chicks	310:333	448 Cobb 500 male chicks	310:333	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	14	59	theme	jejunal	1154:1160	arg1	digestibility					1169:1181	2, jejunal starch digestibility	1151:1181	digestibility	1169:1181	2, jejunal starch digestibility was determined on d 24.					
36565629	21	60	theme	corn	1895:1898	arg1	nutrient					1871:1878	nutrient	1871:1878	nutrient	1871:1878	In conclusion, energy and nutrient utilization of corn by broilers depend on the region where it was grown.					
36565629	21	60	theme	corn	1895:1898	arg1	energy					1860:1865	energy	1860:1865	energy	1860:1865	In conclusion, energy and nutrient utilization of corn by broilers depend on the region where it was grown.					
36565629	4	61	from	located	419:425	arg1	North					434:438	the North	430:438	the North	430:438	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	4	61	from	located	419:425	arg1	South					443:447	South	443:447	South	443:447	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	22	62	theme	Corn	1953:1956	arg1	genetics					1958:1965	Corn genetics	1953:1965	Corn genetics	1953:1965	Corn genetics, expressed by the endosperm composition, and carbohydrase supplementation influenced energy and nutrient utilization by broilers.					
36565629	22	63	dep	energy	2052:2057	arg1	utilization					2072:2082	utilization	2072:2082	utilization	2072:2082	Corn genetics, expressed by the endosperm composition, and carbohydrase supplementation influenced energy and nutrient utilization by broilers.					
36565629	19	64	theme	N	1724:1724	arg1	digestibility					1707:1719	the highest digestibility	1695:1719	the highest digestibility of N and starch	1695:1735	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	17	65	theme	≤	1541:1541	arg1	non-supplemented					1515:1530	non-supplemented	1515:1530	non-supplemented	1515:1530	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	17	65	theme	≤	1541:1541	arg1	P					1539:1539	P ≤ 0.01	1539:1546	P ≤ 0.01	1539:1546	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	2	66	with	utilization	227:237	arg1	compositions					262:273	different compositions	252:273	different compositions	252:273	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	4	67	theme	located	419:425	arg1	regions					396:402	regions	396:402	regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation	396:491	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	19	68	theme	starch	1730:1735	arg1	digestibility					1707:1719	the highest digestibility	1695:1719	the highest digestibility of N and starch	1695:1735	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	69	located	observed	1609:1616	arg1	corn					1636:1639	corn	1636:1639	corn	1636:1639	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	69	located	observed	1609:1616	arg2	2					1558:1558	2	1558:1558	2	1558:1558	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	69	located	observed	1609:1616	arg2	values					1576:1581	the highest ME values	1561:1581	the highest ME values	1561:1581	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	69	located	observed	1609:1616	arg2	digestibility					1590:1602	EE digestibility	1587:1602	EE digestibility	1587:1602	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	7	70	dep	d	816:816	arg1	to					821:822	to	821:822	to	821:822	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	2	71	theme	corn	242:245	arg1	nutrient					207:214	nutrient	207:214	nutrient	207:214	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	2	71	theme	corn	242:245	arg1	utilization					227:237	energy utilization	220:237	energy utilization	220:237	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	20	72	contain	had	1786:1788	arg1	diets					1743:1747	Corn diets	1738:1747	Corn diets supplemented with amylase + xylanase	1738:1784	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	20	72	contain	had	1786:1788	arg2	improvements					1790:1801	improvements	1790:1801	improvements of 2.5% AMEn and 3% starch digestibility	1790:1842	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	12	73	theme	Ca	1086:1087	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	19	74	theme	ME	1573:1574	arg1	values					1576:1581	the highest ME values	1561:1581	the highest ME values	1561:1581	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	19	74	theme	ME	1573:1574	arg1	2					1558:1558	2	1558:1558	2	1558:1558	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	4	75	theme	carbohydrases	463:475	arg1	supplementation					477:491	Brazil × 4 carbohydrases supplementation	452:491	Brazil × 4 carbohydrases supplementation	452:491	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	6	76	dep	experimental	583:594	arg1	feeds					596:600	feeds	596:600	feeds	596:600	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	9	77	theme	carbohydrase	881:892	arg1	1					852:852	1	852:852	1	852:852	1, α-amylase, β-xylanase, or carbohydrase complex (cellulase, glucanase, and xylanase) were added to the diet.					
36565629	9	77	theme	carbohydrase	881:892	arg1	complex					894:900	carbohydrase complex	881:900	carbohydrase complex (cellulase, glucanase, and xylanase)	881:937	1, α-amylase, β-xylanase, or carbohydrase complex (cellulase, glucanase, and xylanase) were added to the diet.					
36565629	0	78	theme	geographic	79:88	arg1	areas					90:94	geographic areas	79:94	geographic areas	79:94	Research Note: Corn energy and nutrient utilization by broilers as affected by geographic areas and carbohydrases.					
36565629	6	79	theme	factorial	614:622	arg1	arrangement					624:634	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	4	80	dep	cages	512:516	arg1	replicate					502:510	replicate	502:510	replicate	502:510	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	2	81	with	nutrient	207:214	arg1	compositions					262:273	different compositions	252:273	different compositions	252:273	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	4	82	from	regions	396:402	arg1	corn					386:389	corn	386:389	corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation	386:491	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	0	83	theme	Corn	15:18	arg1	energy					20:25	Corn energy	15:25	Corn energy	15:25	Research Note: Corn energy and nutrient utilization by broilers as affected by geographic areas and carbohydrases.					
36565629	20	84	theme	2.5	1806:1808	arg1	%					1809:1809	%	1809:1809	%	1809:1809	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	7	85	theme	%	804:804	arg1	corn					806:809	95.9% corn	800:809	95.9% corn from d 14 to 24 in both studies	800:841	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	20	86	theme	AMEn	1811:1814	arg1	improvements					1790:1801	improvements	1790:1801	improvements of 2.5% AMEn and 3% starch digestibility	1790:1842	Corn diets supplemented with amylase + xylanase had improvements of 2.5% AMEn and 3% starch digestibility.					
36565629	12	87	theme	extract	1072:1078	arg1	Digestibility					1042:1054	Digestibility	1042:1054	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE	1042:1124	Digestibility of DM, N, ether extract (EE), Ca, and P as well as AME, AMEn, and IDE were determined.					
36565629	15	88	theme	variance	1242:1249	arg1	analysis					1230:1237	analysis	1230:1237	analysis of variance	1230:1249	Data were subjected to analysis of variance and means were compared by Tukey test (P ≤ 0.05).					
36565629	4	89	dep	arrangement	373:383	arg1	corn					386:389	corn	386:389	corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation	386:491	1, a total of 448 Cobb 500 male chicks were distributed in a 2 × 4 factorial arrangement (corn from regions geographically located in the North or South of Brazil × 4 carbohydrases supplementation), with 8 replicate cages of 7 birds each.					
36565629	17	90	theme	%	1459:1459	arg1	increases					1445:1453	increases	1445:1453	increases of 3% in AME and 2% in N digestibility	1445:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	2	91	theme	exogenous	180:188	arg1	carbohydrases					190:202	exogenous carbohydrases	180:202	exogenous carbohydrases	180:202	were conducted to evaluate the effects of exogenous carbohydrases on nutrient and energy utilization of corn with different compositions by broilers.					
36565629	17	92	from	%	1473:1473	arg1	AME					1464:1466	AME	1464:1466	AME	1464:1466	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	17	92	from	%	1473:1473	arg1	digestibility					1480:1492	N digestibility	1478:1492	N digestibility	1478:1492	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
36565629	19	93	dep	observed	1609:1616	arg1	whereas					1663:1669	whereas	1663:1669	whereas	1663:1669	2, the highest ME values and EE digestibility were observed in the semi-flint corn compared to the waxy, whereas the semi-dent presented the highest digestibility of N and starch.					
36565629	6	94	dep	arrangement	624:634	arg1	semi-dent					674:682	semi-dent	674:682	semi-dent	674:682	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	94	dep	arrangement	624:634	arg1	semi-flint					688:697	semi-flint	688:697	semi-flint	688:697	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	94	dep	arrangement	624:634	arg1	waxy					668:671	waxy	668:671	waxy	668:671	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	94	dep	arrangement	624:634	arg1	compositions					654:665	[3 corn endosperm compositions	636:665	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	95	theme	endosperm	644:652	arg1	semi-dent					674:682	semi-dent	674:682	semi-dent	674:682	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	95	theme	endosperm	644:652	arg1	semi-flint					688:697	semi-flint	688:697	semi-flint	688:697	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	95	theme	endosperm	644:652	arg1	waxy					668:671	waxy	668:671	waxy	668:671	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	6	95	theme	endosperm	644:652	arg1	compositions					654:665	[3 corn endosperm compositions	636:665	a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases]	606:717	2, 672 Cobb 500 male chicks were fed 12 experimental feeds, in a 3 × 4 factorial arrangement [3 corn endosperm compositions (waxy, semi-dent, or semi-flint) × 4 carbohydrases], with 8 replicate cages of 7 birds.					
36565629	7	96	theme	semi-purified	770:782	arg1	diets					789:793	semi-purified test diets	770:793	semi-purified test diets	770:793	Birds were fed semi-purified test diets with 95.9% corn from d 14 to 24 in both studies.					
36565629	16	97	dep	higher	1332:1337	arg1	AME					1339:1341	AME	1339:1341	AME	1339:1341	Corn from the North origin had higher AME, AMEn, and digestibility of DM and N compared to the South (P ≤ 0.05).					
36565629	21	98	dep	energy	1860:1865	arg1	utilization					1880:1890	utilization	1880:1890	utilization	1880:1890	In conclusion, energy and nutrient utilization of corn by broilers depend on the region where it was grown.					
36565629	17	99	theme	Amylase	1414:1420	arg1	supplementation					1422:1436	Amylase supplementation	1414:1436	Amylase supplementation	1414:1436	Amylase supplementation led to increases of 3% in AME and 2% in N digestibility when compared to the non-supplemented feeds (P ≤ 0.01).					
37318735	5	0	dep	-treated	832:839	arg1	iodide					819:824	ammonium iodide	810:824	ammonium iodide	810:824	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	4	1	theme	sodium	612:617	arg1	solutions					655:663	sodium alginate/activated carbon composite solutions	612:663	sodium alginate/activated carbon composite solutions	612:663	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	7	2	theme	maximum	1157:1163	arg1	36,056.5 μg/g					1243:1255	36,056.5 μg/g	1243:1255	36,056.5 μg/g	1243:1255	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	2	theme	maximum	1157:1163	arg1	capacity					1176:1183	the maximum adsorption capacity	1153:1183	the maximum adsorption capacity of NCA adsorbent composite microspheres	1153:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	5	3	theme	composite	881:889	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	2	4	from	utilization	363:373	arg1	scale					393:397	the industrial scale	378:397	the industrial scale	378:397	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	10	5	theme	equilibrium	1654:1664	arg1	te					1672:1673	te	1672:1673	te	1672:1673	The breakthrough time (tb) and equilibrium time (te) were found to be 7.5 days and 23 days, respectively.					
37318735	10	5	theme	equilibrium	1654:1664	arg1	time					1666:1669	equilibrium time	1654:1669	equilibrium time (te)	1654:1674	The breakthrough time (tb) and equilibrium time (te) were found to be 7.5 days and 23 days, respectively.					
37318735	11	6	theme	potential	1836:1844	arg1	microspheres					1820:1831	NCA composite microspheres	1806:1831	NCA composite microspheres	1806:1831	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	11	6	theme	potential	1836:1844	arg1	adsorbents					1846:1855	potential adsorbents	1836:1855	potential adsorbents for removing Hg° from natural gas	1836:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	1	7	theme	environmental	222:234	arg1	pollutants					236:245	environmental pollutants	222:245	environmental pollutants	222:245	Activated carbon (AC) is an effective adsorbent for removing environmental pollutants.					
37318735	5	8	theme	carbon	868:873	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	4	9	theme	chloride	678:685	arg1	solution					687:694	a calcium chloride solution	668:694	a calcium chloride solution	668:694	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	11	10	theme	natural	1879:1885	arg1	gas					1887:1889	natural gas	1879:1889	natural gas	1879:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	5	11	theme	CAA	751:753	arg1	microspheres					765:776	CAA composite microspheres	751:776	CAA composite microspheres	751:776	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	0	12	theme	carbon	27:32	arg1	Encapsulation					0:12	Encapsulation	0:12	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon	0:100	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	9	13	theme	breakthrough	1552:1563	arg1	curve					1565:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve correlated well with Yoon‒Nelson and Thomas models.					
37318735	2	14	theme	powder	273:278	arg1	form					280:283	the traditional powder form	257:283	the traditional powder form of AC	257:289	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	5	15	theme	NH4I	956:959	arg1	treatment					961:969	NH4I treatment	956:969	NH4I treatment	956:969	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	2	16	from	difficulty	297:306	arg1	handling					311:318	handling	311:318	handling	311:318	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	8	17	theme	free	1364:1367	arg1	ΔG°					1377:1379	ΔG°	1377:1379	ΔG°	1377:1379	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	8	17	theme	free	1364:1367	arg1	energy					1369:1374	The Gibbs free energy	1354:1374	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres	1354:1421	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	11	18	theme	good	1780:1783	arg1	feasibility					1785:1795	a good feasibility	1778:1795	a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas	1778:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	5	19	theme	calcium	841:847	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	6	20	theme	microspheres	1034:1045	arg1	properties					1016:1025	The morphological, structural, and textural properties	972:1025	The morphological, structural, and textural properties of the microspheres	972:1045	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	5	21	theme	simple	923:928	arg1	method					943:948	a simple impregnation method	921:948	a simple impregnation method using NH4I treatment	921:969	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	4	22	theme	Calcium	514:520	arg1	microspheres					564:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	11	23	theme	NCA	1806:1808	arg1	microspheres					1820:1831	NCA composite microspheres	1806:1831	NCA composite microspheres	1806:1831	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	11	23	theme	NCA	1806:1808	arg1	adsorbents					1846:1855	potential adsorbents	1836:1855	potential adsorbents for removing Hg° from natural gas	1836:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	5	24	theme	microspheres	765:776	arg1	affinity					739:746	adsorption affinity	728:746	adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°)	728:807	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	6	25	theme	textural	1007:1014	arg1	properties					1016:1025	The morphological, structural, and textural properties	972:1025	The morphological, structural, and textural properties of the microspheres	972:1045	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	8	26	theme	NCA	1386:1388	arg1	microspheres					1410:1421	NCA adsorbent composite microspheres	1386:1421	NCA adsorbent composite microspheres	1386:1421	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	3	27	theme	AC	446:447	arg1	powder					449:454	traditional AC powder	434:454	traditional AC powder	434:454	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	5	28	theme	elemental	785:793	arg1	Hg°					804:806	Hg°	804:806	Hg°	804:806	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	5	28	theme	elemental	785:793	arg1	mercury					795:801	elemental mercury	785:801	elemental mercury (Hg°)	785:807	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	0	29	theme	calcium	39:45	arg1	microspheres					56:67	calcium alginate microspheres	39:67	calcium alginate microspheres toward granular-activated carbon	39:100	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	11	30	attach	removing	1861:1868	arg2	microspheres					1820:1831	NCA composite microspheres	1806:1831	NCA composite microspheres	1806:1831	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	11	30	attach	removing	1861:1868	arg2	adsorbents					1846:1855	potential adsorbents	1836:1855	potential adsorbents for removing Hg° from natural gas	1836:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	11	30	attach	removing	1861:1868	arg1	gas					1887:1889	natural gas	1879:1889	natural gas	1879:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	0	31	theme	granular-activated	76:93	arg1	carbon					95:100	granular-activated carbon	76:100	granular-activated carbon	76:100	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	8	32	theme	composite	1400:1408	arg1	microspheres					1410:1421	NCA adsorbent composite microspheres	1386:1421	NCA adsorbent composite microspheres	1386:1421	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	4	33	theme	composite	554:562	arg1	microspheres					564:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	9	34	dep	Yoon‒Nelson	1592:1602	arg1	models					1615:1620	models	1615:1620	models	1615:1620	The experimental Hg° breakthrough curve correlated well with Yoon‒Nelson and Thomas models.					
37318735	0	35	theme	activated	17:25	arg1	carbon					27:32	activated carbon	17:32	activated carbon	17:32	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	6	36	theme	adsorptive	1080:1089	arg1	capacity					1091:1098	their Hg° adsorptive capacity	1070:1098	their Hg° adsorptive capacity	1070:1098	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	3	37	theme	such	417:420	arg1	limitation					422:431	such limitation	417:431	such limitation	417:431	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	7	38	theme	initial	1331:1337	arg1	concentration					1339:1351	Hg° initial concentration	1327:1351	Hg° initial concentration	1327:1351	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	39	theme	composite	1202:1210	arg1	microspheres					1212:1223	NCA adsorbent composite microspheres	1188:1223	NCA adsorbent composite microspheres	1188:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	5	40	theme	ammonium	810:817	arg1	iodide					819:824	ammonium iodide	810:824	ammonium iodide	810:824	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	7	41	theme	concentration	1339:1351	arg1	500 μg/Nm3					1313:1322	500 μg/Nm3	1313:1322	500 μg/Nm3 of Hg° initial concentration	1313:1351	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	41	theme	concentration	1339:1351	arg1	temperature					1287:1297	temperature	1287:1297	temperature of 25 °C	1287:1306	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	41	theme	concentration	1339:1351	arg1	rate					1267:1270	a flow rate	1260:1270	a flow rate of 250 mL/min	1260:1284	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	4	42	theme	carbon	541:546	arg1	microspheres					564:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	3	43	theme	CA	496:497	arg1	microspheres					500:511	calcium alginate (CA) microspheres	478:511	calcium alginate (CA) microspheres	478:511	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	0	44	theme	alginate	47:54	arg1	microspheres					56:67	calcium alginate microspheres	39:67	calcium alginate microspheres toward granular-activated carbon	39:100	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	7	45	theme	Hg°	1327:1329	arg1	concentration					1339:1351	Hg° initial concentration	1327:1351	Hg° initial concentration	1327:1351	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	4	46	theme	CAA	549:551	arg1	microspheres					564:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	8	47	theme	adsorption	1485:1494	arg1	process					1496:1502	a spontaneous adsorption process	1471:1502	a spontaneous adsorption process with an exothermic nature	1471:1528	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	3	48	theme	alginate	486:493	arg1	microspheres					500:511	calcium alginate (CA) microspheres	478:511	calcium alginate (CA) microspheres	478:511	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	4	49	theme	alginate/activated	619:636	arg1	solutions					655:663	sodium alginate/activated carbon composite solutions	612:663	sodium alginate/activated carbon composite solutions	612:663	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	11	50	theme	work	1764:1767	arg1	findings					1747:1754	the findings	1743:1754	the findings of this work	1743:1767	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	2	51	theme	industrial	382:391	arg1	scale					393:397	the industrial scale	378:397	the industrial scale	378:397	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	4	52	theme	composite	645:653	arg1	solutions					655:663	sodium alginate/activated carbon composite solutions	612:663	sodium alginate/activated carbon composite solutions	612:663	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	7	53	theme	adsorption	1165:1174	arg1	36,056.5 μg/g					1243:1255	36,056.5 μg/g	1243:1255	36,056.5 μg/g	1243:1255	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	53	theme	adsorption	1165:1174	arg1	capacity					1176:1183	the maximum adsorption capacity	1153:1183	the maximum adsorption capacity of NCA adsorbent composite microspheres	1153:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	2	54	theme	AC	288:289	arg1	form					280:283	the traditional powder form	257:283	the traditional powder form of AC	257:289	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	7	55	theme	NCA	1188:1190	arg1	microspheres					1212:1223	NCA adsorbent composite microspheres	1188:1223	NCA adsorbent composite microspheres	1188:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	0	56	theme	natural	148:154	arg1	gas					156:158	natural gas	148:158	natural gas	148:158	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	5	57	theme	alginate/activated	849:866	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	6	58	theme	structural	991:1000	arg1	properties					1016:1025	The morphological, structural, and textural properties	972:1025	The morphological, structural, and textural properties of the microspheres	972:1045	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	8	59	theme	exothermic	1512:1521	arg1	nature					1523:1528	an exothermic nature	1509:1528	an exothermic nature	1509:1528	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	9	60	theme	Hg°	1548:1550	arg1	curve					1565:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve correlated well with Yoon‒Nelson and Thomas models.					
37318735	6	61	theme	morphological	976:988	arg1	properties					1016:1025	The morphological, structural, and textural properties	972:1025	The morphological, structural, and textural properties of the microspheres	972:1045	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	4	62	theme	calcium	670:676	arg1	solution					687:694	a calcium chloride solution	668:694	a calcium chloride solution	668:694	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	5	63	theme	composite	755:763	arg1	microspheres					765:776	CAA composite microspheres	751:776	CAA composite microspheres	751:776	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	5	64	theme	impregnation	930:941	arg1	method					943:948	a simple impregnation method	921:948	a simple impregnation method using NH4I treatment	921:969	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	5	65	theme	adsorption	728:737	arg1	affinity					739:746	adsorption affinity	728:746	adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°)	728:807	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	7	66	theme	250 mL/min	1275:1284	arg1	500 μg/Nm3					1313:1322	500 μg/Nm3	1313:1322	500 μg/Nm3 of Hg° initial concentration	1313:1351	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	66	theme	250 mL/min	1275:1284	arg1	temperature					1287:1297	temperature	1287:1297	temperature of 25 °C	1287:1306	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	66	theme	250 mL/min	1275:1284	arg1	rate					1267:1270	a flow rate	1260:1270	a flow rate of 250 mL/min	1260:1284	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	2	67	theme	traditional	261:271	arg1	form					280:283	the traditional powder form	257:283	the traditional powder form of AC	257:289	However, the traditional powder form of AC shows difficulty in handling during application which widely limits its utilization on the industrial scale.					
37318735	1	68	theme	Activated	161:169	arg1	carbon					171:176	Activated carbon	161:176	Activated carbon (AC)	161:181	Activated carbon (AC) is an effective adsorbent for removing environmental pollutants.					
37318735	1	68	theme	Activated	161:169	arg1	effective					189:197	effective	189:197	effective	189:197	Activated carbon (AC) is an effective adsorbent for removing environmental pollutants.					
37318735	1	68	theme	Activated	161:169	arg1	AC					179:180	AC	179:180	AC	179:180	Activated carbon (AC) is an effective adsorbent for removing environmental pollutants.					
37318735	8	69	theme	Gibbs	1358:1362	arg1	ΔG°					1377:1379	ΔG°	1377:1379	ΔG°	1377:1379	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	8	69	theme	Gibbs	1358:1362	arg1	energy					1369:1374	The Gibbs free energy	1354:1374	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres	1354:1421	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	7	70	theme	flow	1262:1265	arg1	rate					1267:1270	a flow rate	1260:1270	a flow rate of 250 mL/min	1260:1284	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	4	71	theme	alginate/activated	522:539	arg1	microspheres					564:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres	514:575	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	0	72	theme	elemental	117:125	arg1	capture					135:141	elemental mercury capture	117:141	elemental mercury capture from natural gas	117:158	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	11	73	theme	composite	1810:1818	arg1	microspheres					1820:1831	NCA composite microspheres	1806:1831	NCA composite microspheres	1806:1831	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	11	73	theme	composite	1810:1818	arg1	adsorbents					1846:1855	potential adsorbents	1836:1855	potential adsorbents for removing Hg° from natural gas	1836:1889	Collectively, the findings of this work indicate a good feasibility of using NCA composite microspheres as potential adsorbents for removing Hg° from natural gas.					
37318735	4	74	from	cross-linking	595:607	arg1	solution					687:694	a calcium chloride solution	668:694	a calcium chloride solution	668:694	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	9	75	theme	experimental	1535:1546	arg1	curve					1565:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve	1531:1569	The experimental Hg° breakthrough curve correlated well with Yoon‒Nelson and Thomas models.					
37318735	6	76	theme	different	1114:1122	arg1	temperatures					1124:1135	different temperatures	1114:1135	different temperatures	1114:1135	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	0	77	from	gas	156:158	arg1	capture					135:141	elemental mercury capture	117:141	elemental mercury capture from natural gas	117:158	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	8	78	theme	adsorbent	1390:1398	arg1	microspheres					1410:1421	NCA adsorbent composite microspheres	1386:1421	NCA adsorbent composite microspheres	1386:1421	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	3	79	theme	traditional	434:444	arg1	powder					449:454	traditional AC powder	434:454	traditional AC powder	434:454	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	7	80	theme	microspheres	1212:1223	arg1	36,056.5 μg/g					1243:1255	36,056.5 μg/g	1243:1255	36,056.5 μg/g	1243:1255	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	80	theme	microspheres	1212:1223	arg1	capacity					1176:1183	the maximum adsorption capacity	1153:1183	the maximum adsorption capacity of NCA adsorbent composite microspheres	1153:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	5	81	theme	-treated	832:839	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	3	82	theme	calcium	478:484	arg1	microspheres					500:511	calcium alginate (CA) microspheres	478:511	calcium alginate (CA) microspheres	478:511	Herein, to avoid such limitation, traditional AC powder was encapsulated into calcium alginate (CA) microspheres.					
37318735	7	83	theme	adsorbent	1192:1200	arg1	microspheres					1212:1223	NCA adsorbent composite microspheres	1188:1223	NCA adsorbent composite microspheres	1188:1223	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	6	84	theme	Hg°	1076:1078	arg1	capacity					1091:1098	their Hg° adsorptive capacity	1070:1098	their Hg° adsorptive capacity	1070:1098	The morphological, structural, and textural properties of the microspheres were characterized and their Hg° adsorptive capacity was tested at different temperatures.					
37318735	0	85	theme	mercury	127:133	arg1	capture					135:141	elemental mercury capture	117:141	elemental mercury capture from natural gas	117:158	Encapsulation of activated carbon into calcium alginate microspheres toward granular-activated carbon adsorbents for elemental mercury capture from natural gas.					
37318735	4	86	theme	carbon	638:643	arg1	solutions					655:663	sodium alginate/activated carbon composite solutions	612:663	sodium alginate/activated carbon composite solutions	612:663	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	8	87	theme	spontaneous	1473:1483	arg1	process					1496:1502	a spontaneous adsorption process	1471:1502	a spontaneous adsorption process with an exothermic nature	1471:1528	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
37318735	5	88	theme	NCA	876:878	arg1	microspheres					891:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres	810:902	Furthermore, in order to boost adsorption affinity of CAA composite microspheres toward elemental mercury (Hg°), ammonium iodide (NH4I)-treated calcium alginate/activated carbon (NCA) composite microspheres were obtained by a simple impregnation method using NH4I treatment.					
37318735	7	89	theme	25 °C	1302:1306	arg1	500 μg/Nm3					1313:1322	500 μg/Nm3	1313:1322	500 μg/Nm3 of Hg° initial concentration	1313:1351	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	89	theme	25 °C	1302:1306	arg1	temperature					1287:1297	temperature	1287:1297	temperature of 25 °C	1287:1306	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	7	89	theme	25 °C	1302:1306	arg1	rate					1267:1270	a flow rate	1260:1270	a flow rate of 250 mL/min	1260:1284	Interestingly, the maximum adsorption capacity of NCA adsorbent composite microspheres was determined as 36,056.5 μg/g at a flow rate of 250 mL/min, temperature of 25 °C, and 500 μg/Nm3 of Hg° initial concentration.					
37318735	4	90	theme	solutions	655:663	arg1	cross-linking					595:607	cross-linking	595:607	cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution	595:694	Calcium alginate/activated carbon (CAA) composite microspheres were prepared via cross-linking of sodium alginate/activated carbon composite solutions in a calcium chloride solution.					
37318735	10	91	theme	breakthrough	1627:1638	arg1	tb					1646:1647	tb	1646:1647	tb	1646:1647	The breakthrough time (tb) and equilibrium time (te) were found to be 7.5 days and 23 days, respectively.					
37318735	10	91	theme	breakthrough	1627:1638	arg1	time					1640:1643	The breakthrough time	1623:1643	The breakthrough time (tb)	1623:1648	The breakthrough time (tb) and equilibrium time (te) were found to be 7.5 days and 23 days, respectively.					
37318735	10	91	theme	breakthrough	1627:1638	arg1	7.5 days					1693:1700	7.5 days	1693:1700	7.5 days	1693:1700	The breakthrough time (tb) and equilibrium time (te) were found to be 7.5 days and 23 days, respectively.					
37318735	8	92	with	process	1496:1502	arg1	nature					1523:1528	an exothermic nature	1509:1528	an exothermic nature	1509:1528	The Gibbs free energy (ΔG°) for NCA adsorbent composite microspheres varied from - 8.59 to - 10.54 kJ/mol indicating a spontaneous adsorption process with an exothermic nature.					
35661170	9	0	from	study	1321:1325	arg1	properties					1400:1409	various protein properties	1384:1409	various protein properties	1384:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	5	1	theme	fluctuation	856:866	arg1	dynamics					868:875	the conformational fluctuation dynamics	837:875	the conformational fluctuation dynamics	837:875	For example, all the crowders increased the α-helicity of HSA and hindered the conformational fluctuation dynamics.					
35661170	6	2	with	HSA	1031:1033	arg1	PEG-35					1054:1059	PEG-35	1054:1059	PEG-35	1054:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	6	2	with	HSA	1031:1033	arg1	Ficoll-70					1040:1048	Ficoll-70	1040:1048	Ficoll-70	1040:1048	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	9	3	theme	shape-dependent	1334:1348	arg1	effect					1374:1379	the shape-dependent macromolecular crowding effect	1330:1379	the shape-dependent macromolecular crowding effect on various protein properties	1330:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	2	4	theme	serum	540:544	arg1	HSA					555:557	HSA	555:557	HSA	555:557	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	4	theme	serum	540:544	arg1	albumin					546:552	multi-domain human serum albumin	521:552	multi-domain human serum albumin (HSA)	521:558	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	5	dep	structure	432:440	arg1	the					428:430	the	428:430	the	428:430	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	9	6	theme	crowding	1483:1490	arg1	mechanism					1455:1463	the mechanism	1451:1463	the mechanism of macromolecular crowding	1451:1490	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	9	7	theme	macromolecular	1350:1363	arg1	effect					1374:1379	the shape-dependent macromolecular crowding effect	1330:1379	the shape-dependent macromolecular crowding effect on various protein properties	1330:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	0	8	theme	conformational	83:96	arg1	dynamics					98:105	conformational dynamics	83:105	conformational dynamics	83:105	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	1	9	theme	charges	247:253	arg1	macromolecules					202:215	macromolecules	202:215	macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics	202:310	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
35661170	3	10	from	charges	607:613	arg1	region					657:662	the dilute region	646:662	the dilute region	646:662	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	3	11	theme	different	669:677	arg1	shapes					679:684	different shapes	669:684	different shapes	669:684	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	6	12	with	line	916:919	arg1	increase					955:962	an increase	952:962	an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	952:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	6	12	with	line	916:919	arg1	expectations					930:941	the expectations	926:941	the expectations	926:941	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	6	13	theme	HSA	1031:1033	arg1	PEG-35					988:993	PEG-35	988:993	PEG-35	988:993	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	6	13	theme	HSA	1031:1033	arg1	movement					1019:1026	uncorrelated domain movement	999:1026	uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	999:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	9	14	theme	effect	1374:1379	arg1	study					1321:1325	a somewhat systematic study	1299:1325	a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties	1299:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	2	15	theme	domain	502:507	arg1	movement					509:516	relative domain movement	493:516	relative domain movement	493:516	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	4	16	theme	traditional	733:743	arg1	theory					754:759	the traditional crowding theory	729:759	the traditional crowding theory	729:759	Some observations follow the traditional crowding theory.					
35661170	6	17	theme	uncorrelated	999:1010	arg1	movement					1019:1026	uncorrelated domain movement	999:1026	uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	999:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	2	18	theme	crowders	382:389	arg1	effect					341:346	the effect	337:346	the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA)	337:558	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	19	theme	relative	493:500	arg1	movement					509:516	relative domain movement	493:516	relative domain movement	493:516	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	3	20	from	compositions	690:701	arg1	region					657:662	the dilute region	646:662	the dilute region	646:662	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	8	21	from	nature	1262:1267	arg1	hydrophobic					1247:1257	hydrophobic	1247:1257	hydrophobic	1247:1257	The interaction between HSA and Ficoll-70 is proposed to be hydrophobic in nature.					
35661170	8	21	from	nature	1262:1267	arg1	interaction					1191:1201	The interaction	1187:1201	The interaction between HSA and Ficoll-70	1187:1227	The interaction between HSA and Ficoll-70 is proposed to be hydrophobic in nature.					
35661170	1	22	theme	cellular	167:174	arg1	environment					176:186	The cellular environment	163:186	The cellular environment	163:186	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
35661170	9	23	theme	macromolecular	1468:1481	arg1	crowding					1483:1490	macromolecular crowding	1468:1490	macromolecular crowding	1468:1490	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	2	24	theme	different	357:365	arg1	dextran-40					392:401	dextran-40	392:401	dextran-40	392:401	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	24	theme	different	357:365	arg1	crowders					382:389	three different macromolecular crowders	351:389	three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35	351:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	24	theme	different	357:365	arg1	PEG-35					418:423	PEG-35	418:423	PEG-35	418:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	24	theme	different	357:365	arg1	Ficoll-70					404:412	Ficoll-70	404:412	Ficoll-70	404:412	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	0	25	theme	Macromolecular	0:13	arg1	crowding					15:22	Macromolecular crowding:	0:23	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein	0:160	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	8	26	from	hydrophobic	1247:1257	arg1	nature					1262:1267	nature	1262:1267	nature	1262:1267	The interaction between HSA and Ficoll-70 is proposed to be hydrophobic in nature.					
35661170	5	27	theme	HSA	820:822	arg1	α-helicity					806:815	the α-helicity	802:815	the α-helicity of HSA	802:822	For example, all the crowders increased the α-helicity of HSA and hindered the conformational fluctuation dynamics.					
35661170	6	28	from	increase	955:962	arg1	size					971:974	the size	967:974	the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	967:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	2	29	dep	crowders	382:389	arg1	dextran-40					392:401	dextran-40	392:401	dextran-40	392:401	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	29	dep	crowders	382:389	arg1	crowders					382:389	three different macromolecular crowders	351:389	three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35	351:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	29	dep	crowders	382:389	arg1	PEG-35					418:423	PEG-35	418:423	PEG-35	418:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	29	dep	crowders	382:389	arg1	Ficoll-70					404:412	Ficoll-70	404:412	Ficoll-70	404:412	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	0	30	theme	domain	120:125	arg1	movement					127:134	relative domain movement	111:134	relative domain movement	111:134	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	2	31	from	effect	341:346	arg1	function					480:487	function	480:487	function	480:487	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	31	from	effect	341:346	arg1	dynamics					470:477	active-site conformational dynamics	443:477	active-site conformational dynamics	443:477	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	31	from	effect	341:346	arg1	movement					509:516	relative domain movement	493:516	relative domain movement	493:516	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	31	from	effect	341:346	arg1	structure					432:440	structure	432:440	structure	432:440	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	0	32	dep	structure	62:70	arg1	the					58:60	the	58:60	the	58:60	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	6	33	theme	domain	1012:1017	arg1	movement					1019:1026	uncorrelated domain movement	999:1026	uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	999:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	3	34	from	shapes	679:684	arg1	region					657:662	the dilute region	646:662	the dilute region	646:662	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	1	35	theme	protein	271:277	arg1	structure					279:287	protein structure	271:287	protein structure	271:287	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
35661170	0	36	theme	relative	111:118	arg1	movement					127:134	relative domain movement	111:134	relative domain movement	111:134	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	2	37	theme	conformational	455:468	arg1	dynamics					470:477	active-site conformational dynamics	443:477	active-site conformational dynamics	443:477	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	38	theme	human	534:538	arg1	HSA					555:557	HSA	555:557	HSA	555:557	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	38	theme	human	534:538	arg1	albumin					546:552	multi-domain human serum albumin	521:552	multi-domain human serum albumin (HSA)	521:558	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	3	39	theme	similar	619:625	arg1	sizes					627:631	similar sizes	619:631	similar sizes (at least in the dilute region)	619:663	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	6	40	theme	HSA	979:981	arg1	size					971:974	the size	967:974	the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	967:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	2	41	theme	active-site	443:453	arg1	dynamics					470:477	active-site conformational dynamics	443:477	active-site conformational dynamics	443:477	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	42	theme	multi-domain	521:532	arg1	HSA					555:557	HSA	555:557	HSA	555:557	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	42	theme	multi-domain	521:532	arg1	albumin					546:552	multi-domain human serum albumin	521:552	multi-domain human serum albumin (HSA)	521:558	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	9	43	theme	possible	1425:1432	arg1	insight					1438:1444	a possible new insight	1423:1444	a possible new insight into the mechanism of macromolecular crowding	1423:1490	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	7	44	theme	relative	1066:1073	arg1	movement					1082:1089	The relative domain movement	1062:1089	The relative domain movement	1062:1089	The relative domain movement is correlated with the activity, suggesting that such moves are essential for protein function.					
35661170	9	45	theme	various	1384:1390	arg1	properties					1400:1409	various protein properties	1384:1409	various protein properties	1384:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	0	46	theme	multi-domain	141:152	arg1	protein					154:160	a multi-domain protein	139:160	a multi-domain protein	139:160	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	9	47	theme	new	1434:1436	arg1	insight					1438:1444	a possible new insight	1423:1444	a possible new insight into the mechanism of macromolecular crowding	1423:1490	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	7	48	theme	domain	1075:1080	arg1	movement					1082:1089	The relative domain movement	1062:1089	The relative domain movement	1062:1089	The relative domain movement is correlated with the activity, suggesting that such moves are essential for protein function.					
35661170	2	49	theme	albumin	546:552	arg1	function					480:487	function	480:487	function	480:487	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	49	theme	albumin	546:552	arg1	dynamics					470:477	active-site conformational dynamics	443:477	active-site conformational dynamics	443:477	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	49	theme	albumin	546:552	arg1	movement					509:516	relative domain movement	493:516	relative domain movement	493:516	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	49	theme	albumin	546:552	arg1	structure					432:440	structure	432:440	structure	432:440	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	6	50	with	HSA	979:981	arg1	PEG-35					988:993	PEG-35	988:993	PEG-35	988:993	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	6	50	with	HSA	979:981	arg1	movement					1019:1026	uncorrelated domain movement	999:1026	uncorrelated domain movement of HSA with Ficoll-70 and PEG-35	999:1059	However, some observations are not in line with the expectations, such as an increase in the size of HSA with PEG-35 and uncorrelated domain movement of HSA with Ficoll-70 and PEG-35.					
35661170	7	51	theme	such	1140:1143	arg1	moves					1145:1149	such moves	1140:1149	such moves	1140:1149	The relative domain movement is correlated with the activity, suggesting that such moves are essential for protein function.					
35661170	9	52	theme	systematic	1310:1319	arg1	study					1321:1325	a somewhat systematic study	1299:1325	a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties	1299:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	1	53	theme	various	220:226	arg1	sizes					228:232	various sizes	220:232	various sizes	220:232	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
35661170	0	54	theme	protein	154:160	arg1	movement					127:134	relative domain movement	111:134	relative domain movement	111:134	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	0	54	theme	protein	154:160	arg1	function					73:80	function	73:80	function	73:80	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	0	54	theme	protein	154:160	arg1	dynamics					98:105	conformational dynamics	83:105	conformational dynamics	83:105	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	0	54	theme	protein	154:160	arg1	structure					62:70	structure	62:70	structure	62:70	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	4	55	theme	crowding	745:752	arg1	theory					754:759	the traditional crowding theory	729:759	the traditional crowding theory	729:759	Some observations follow the traditional crowding theory.					
35661170	9	56	theme	protein	1392:1398	arg1	properties					1400:1409	various protein properties	1384:1409	various protein properties	1384:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	1	57	theme	sizes	228:232	arg1	macromolecules					202:215	macromolecules	202:215	macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics	202:310	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
35661170	3	58	from	sizes	627:631	arg1	region					657:662	the dilute region	646:662	the dilute region	646:662	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	0	59	dep	crowding	15:22	arg1	affect					51:56	affect	51:56	affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein	51:160	Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein.					
35661170	9	60	from	properties	1400:1409	arg1	study					1321:1325	a somewhat systematic study	1299:1325	a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties	1299:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	2	61	theme	macromolecular	367:380	arg1	dextran-40					392:401	dextran-40	392:401	dextran-40	392:401	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	61	theme	macromolecular	367:380	arg1	crowders					382:389	three different macromolecular crowders	351:389	three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35	351:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	61	theme	macromolecular	367:380	arg1	PEG-35					418:423	PEG-35	418:423	PEG-35	418:423	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	2	61	theme	macromolecular	367:380	arg1	Ficoll-70					404:412	Ficoll-70	404:412	Ficoll-70	404:412	Herein, we contemplated the effect of three different macromolecular crowders: dextran-40, Ficoll-70 and PEG-35 on the structure, active-site conformational dynamics, function and relative domain movement of multi-domain human serum albumin (HSA).					
35661170	3	62	contain	have	597:600	arg1	crowders					569:576	All the crowders	561:576	All the crowders used in this study	561:595	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	3	62	contain	have	597:600	arg2	sizes					627:631	similar sizes	619:631	similar sizes (at least in the dilute region)	619:663	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	3	62	contain	have	597:600	arg2	charges					607:613	zero charges	602:613	zero charges	602:613	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	9	63	theme	crowding	1365:1372	arg1	effect					1374:1379	the shape-dependent macromolecular crowding effect	1330:1379	the shape-dependent macromolecular crowding effect on various protein properties	1330:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	3	64	theme	dilute	650:655	arg1	region					657:662	the dilute region	646:662	the dilute region	646:662	All the crowders used in this study have zero charges and similar sizes (at least in the dilute region) but different shapes and compositions.					
35661170	9	65	from	effect	1374:1379	arg1	properties					1400:1409	various protein properties	1384:1409	various protein properties	1384:1409	Overall, our results provide a somewhat systematic study of the shape-dependent macromolecular crowding effect on various protein properties and present a possible new insight into the mechanism of macromolecular crowding.					
35661170	5	66	theme	conformational	841:854	arg1	dynamics					868:875	the conformational fluctuation dynamics	837:875	the conformational fluctuation dynamics	837:875	For example, all the crowders increased the α-helicity of HSA and hindered the conformational fluctuation dynamics.					
35661170	7	67	theme	protein	1169:1175	arg1	function					1177:1184	protein function	1169:1184	protein function	1169:1184	The relative domain movement is correlated with the activity, suggesting that such moves are essential for protein function.					
35661170	1	68	theme	shapes	235:240	arg1	macromolecules					202:215	macromolecules	202:215	macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics	202:310	The cellular environment is crowded by macromolecules of various sizes, shapes, and charges, which modulate protein structure, function and dynamics.					
37119888	10	0	theme	%	1536:1536	arg1	absorbency					1546:1555	435 % exudate absorbency	1532:1555	435 % exudate absorbency	1532:1555	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	10	1	theme	%	1420:1420	arg1	elongation					1422:1431	1.24 % elongation	1415:1431	1.24 % elongation	1415:1431	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	10	1	theme	%	1420:1420	arg1	cN					1411:1412	174 cN	1407:1412	174 cN (1.24 % elongation)	1407:1432	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	6	2	theme	scanning	913:920	arg1	DSC					935:937	DSC	935:937	DSC	935:937	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	6	2	theme	scanning	913:920	arg1	calorimeter					922:932	differential scanning calorimeter	900:932	differential scanning calorimeter (DSC)	900:938	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	10	3	theme	exudate	1444:1450	arg1	absorbency					1452:1461	432 % exudate absorbency	1438:1461	432 % exudate absorbency	1438:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	1	4	theme	biomedical	189:198	arg1	field					200:204	the biomedical field	185:204	the biomedical field	185:204	Hydrogels which become increasingly important in the biomedical field are composed of a three-dimensional hydrophilic network.					
37119888	6	5	dep	transform	820:828	arg1	infrared					830:837	infrared	830:837	transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC)	820:938	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	2	6	dep	weak	290:293	arg1	assimilated					338:348	assimilated	338:348	are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels	334:428	Pure hydrogels are usually weak and brittle; therefore, reinforcements are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels.					
37119888	10	7	theme	432 	1438:1441	arg1	%					1442:1442	%	1442:1442	%	1442:1442	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	11	8	from	strength	1652:1659	arg1	absorbency					1754:1763	exudate absorbency	1746:1763	exudate absorbency (p-value 0.043)	1746:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	8	from	strength	1652:1659	arg1	0.043					1774:1778	p-value 0.043	1766:1778	p-value 0.043	1766:1778	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	9	9	theme	alginate	1260:1267	arg1	fiber					1278:1282	the alginate hydrogel fiber	1256:1282	the alginate hydrogel fiber	1256:1282	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	12	10	theme	promising	1944:1952	arg1	option					1954:1959	a promising option	1942:1959	a promising option for use as wound dressings	1942:1986	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	9	11	theme	fiber	1278:1282	arg1	strength					1244:1251	the strength	1240:1251	the strength of the alginate hydrogel fiber	1240:1282	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	7	12	theme	water	1041:1045	arg1	absorbency					1047:1056	water absorbency	1041:1056	water absorbency	1041:1056	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	1	13	theme	three-dimensional	224:240	arg1	network					254:260	a three-dimensional hydrophilic network	222:260	a three-dimensional hydrophilic network	222:260	Hydrogels which become increasingly important in the biomedical field are composed of a three-dimensional hydrophilic network.					
37119888	5	14	theme	hydrogel	720:727	arg1	fibers					729:734	hydrogel fibers	720:734	hydrogel fibers	720:734	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	0	15	theme	hydrogel	69:76	arg1	fibers					78:83	alginate hydrogel fibers	60:83	alginate hydrogel fibers loaded with diclofenac sodium for wound dressings	60:133	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	9	16	theme	better	1315:1320	arg1	properties					1333:1342	better mechanical properties	1315:1342	better mechanical properties	1315:1342	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	7	17	theme	percent	995:1001	arg1	effect					945:950	The effect	941:950	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency	941:1056	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	10	18	theme	hemp	1470:1473	arg1	reinforcement					1475:1487	hemp reinforcement	1470:1487	hemp reinforcement	1470:1487	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	11	19	theme	p-value	1766:1772	arg1	absorbency					1754:1763	exudate absorbency	1746:1763	exudate absorbency (p-value 0.043)	1746:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	19	theme	p-value	1766:1772	arg1	0.043					1774:1778	p-value 0.043	1766:1778	p-value 0.043	1766:1778	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	7	20	theme	fiber	982:986	arg1	percent					995:1001	fiber weight percent	982:1001	fiber weight percent	982:1001	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	0	21	theme	diclofenac	97:106	arg1	sodium					108:113	diclofenac sodium	97:113	diclofenac sodium	97:113	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	5	22	theme	Kapok	644:648	arg1	reinforcement					679:691	reinforcement	679:691	reinforcement	679:691	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	5	22	theme	Kapok	644:648	arg1	fibers					659:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	2	23	theme	hydrogels	420:428	arg1	strength					404:411	the mechanical strength	389:411	the mechanical strength of the hydrogels	389:428	Pure hydrogels are usually weak and brittle; therefore, reinforcements are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels.					
37119888	8	24	theme	sodium	1082:1087	arg1	drug					1089:1092	Diclofenac sodium drug	1071:1092	Diclofenac sodium drug	1071:1092	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	7	25	theme	concentration	964:976	arg1	effect					945:950	The effect	941:950	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency	941:1056	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	10	26	theme	%	1514:1514	arg1	cN					1505:1506	185 cN	1501:1506	185 cN (1.48 % elongation)	1501:1526	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	10	26	theme	%	1514:1514	arg1	elongation					1516:1525	1.48 % elongation	1509:1525	1.48 % elongation	1509:1525	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	4	27	theme	dressing	591:598	arg1	application					600:610	wound dressing application	585:610	wound dressing application	585:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	10	28	theme	Kapok	1345:1349	arg1	reinforcement					1351:1363	Kapok reinforcement	1345:1363	Kapok reinforcement	1345:1363	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	0	29	theme	natural	34:40	arg1	fibers					42:47	natural fibers	34:47	natural fibers	34:47	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	8	30	theme	hydrogel	1112:1119	arg1	fibers					1121:1126	the hydrogel fibers	1108:1126	the hydrogel fibers	1108:1126	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	12	31	theme	composite	1799:1807	arg1	fibers					1818:1823	these composite hydrogel fibers	1793:1823	these composite hydrogel fibers with improved mechanical properties	1793:1859	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	4	32	theme	fiber-reinforced	538:553	arg1	fibers					574:579	natural fiber-reinforced composite hydrogel fibers	530:579	natural fiber-reinforced composite hydrogel fibers for wound dressing application	530:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	10	33	theme	435 	1532:1535	arg1	%					1536:1536	%	1536:1536	%	1536:1536	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	11	34	theme	alginate	1618:1625	arg1	concentration					1627:1639	sodium alginate concentration	1611:1639	sodium alginate concentration	1611:1639	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	4	35	theme	hydrogel	565:572	arg1	fibers					574:579	natural fiber-reinforced composite hydrogel fibers	530:579	natural fiber-reinforced composite hydrogel fibers for wound dressing application	530:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	11	36	theme	wt	1738:1739	arg1	reinforcement					1723:1735	reinforcement	1723:1735	reinforcement (wt%)	1723:1741	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	36	theme	wt	1738:1739	arg1	%					1740:1740	wt%	1738:1740	wt%	1738:1740	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	6	37	theme	hydrogel	778:785	arg1	fibers					787:792	the prepared composite hydrogel fibers	755:792	the prepared composite hydrogel fibers	755:792	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	1	38	theme	hydrophilic	242:252	arg1	network					254:260	a three-dimensional hydrophilic network	222:260	a three-dimensional hydrophilic network	222:260	Hydrogels which become increasingly important in the biomedical field are composed of a three-dimensional hydrophilic network.					
37119888	12	39	theme	mechanical	1839:1848	arg1	properties					1850:1859	improved mechanical properties	1830:1859	improved mechanical properties	1830:1859	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	6	40	theme	scanning	860:867	arg1	SEM					890:892	SEM	890:892	SEM	890:892	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	6	40	theme	scanning	860:867	arg1	microscopy					878:887	scanning electron microscopy	860:887	scanning electron microscopy (SEM)	860:893	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	11	41	theme	reinforcement	1723:1735	arg1	effects					1600:1606	significant effects	1588:1606	significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043)	1588:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	10	42	theme	cN	1411:1412	arg1	strength					1395:1402	a maximum tensile strength	1377:1402	a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency	1377:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	2	43	theme	mechanical	393:402	arg1	strength					404:411	the mechanical strength	389:411	the mechanical strength of the hydrogels	389:428	Pure hydrogels are usually weak and brittle; therefore, reinforcements are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels.					
37119888	8	44	theme	release	1154:1160	arg1	characteristics					1187:1201	the drug release as well as antibacterial characteristics	1145:1201	the drug release as well as antibacterial characteristics	1145:1201	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	10	45	theme	exudate	1538:1544	arg1	absorbency					1546:1555	435 % exudate absorbency	1532:1555	435 % exudate absorbency	1532:1555	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	11	46	theme	significant	1588:1598	arg1	effects					1600:1606	significant effects	1588:1606	significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043)	1588:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	8	47	theme	antibacterial	1173:1185	arg1	characteristics					1187:1201	the drug release as well as antibacterial characteristics	1145:1201	the drug release as well as antibacterial characteristics	1145:1201	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	10	48	theme	tensile	1387:1393	arg1	strength					1395:1402	a maximum tensile strength	1377:1402	a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency	1377:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	6	49	dep	Fourier	812:818	arg1	transform					820:828	transform	820:828	transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC)	820:938	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	5	50	theme	hemp	654:657	arg1	reinforcement					679:691	reinforcement	679:691	reinforcement	679:691	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	5	50	theme	hemp	654:657	arg1	fibers					659:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	10	51	theme	1.24 	1415:1419	arg1	elongation					1422:1431	1.24 % elongation	1415:1431	1.24 % elongation	1415:1431	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	10	51	theme	1.24 	1415:1419	arg1	cN					1411:1412	174 cN	1407:1412	174 cN (1.24 % elongation)	1407:1432	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	12	52	with	fibers	1818:1823	arg1	properties					1850:1859	improved mechanical properties	1830:1859	improved mechanical properties	1830:1859	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	6	53	theme	differential	900:911	arg1	DSC					935:937	DSC	935:937	DSC	935:937	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	6	53	theme	differential	900:911	arg1	calorimeter					922:932	differential scanning calorimeter	900:932	differential scanning calorimeter (DSC)	900:938	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	11	54	theme	exudate	1681:1687	arg1	absorbency					1689:1698	exudate absorbency	1681:1698	exudate absorbency (p-value 0.020)	1681:1714	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	54	theme	exudate	1681:1687	arg1	0.020					1709:1713	p-value 0.020	1701:1713	p-value 0.020	1701:1713	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	10	55	theme	%	1442:1442	arg1	absorbency					1452:1461	432 % exudate absorbency	1438:1461	432 % exudate absorbency	1438:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	11	56	theme	Statistical	1558:1568	arg1	analysis					1570:1577	Statistical analysis	1558:1577	Statistical analysis	1558:1577	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	5	57	theme	fibers	729:734	arg1	strength					708:715	the strength	704:715	the strength of hydrogel fibers	704:734	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	11	58	from	effects	1600:1606	arg1	p-value					1662:1668	p-value 0.042	1662:1674	p-value 0.042	1662:1674	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	58	from	effects	1600:1606	arg1	strength					1652:1659	tensile strength	1644:1659	tensile strength (p-value 0.042)	1644:1675	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	12	59	theme	wound	1972:1976	arg1	dressings					1978:1986	wound dressings	1972:1986	wound dressings	1972:1986	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	6	60	theme	fibers	787:792	arg1	properties					741:750	The properties	737:750	The properties of the prepared composite hydrogel fibers	737:792	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	9	61	theme	hydrogel	1269:1276	arg1	fiber					1278:1282	the alginate hydrogel fiber	1256:1282	the alginate hydrogel fiber	1256:1282	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	2	62	theme	Pure	263:266	arg1	hydrogels					268:276	Pure hydrogels	263:276	Pure hydrogels	263:276	Pure hydrogels are usually weak and brittle; therefore, reinforcements are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels.					
37119888	7	63	from	effect	945:950	arg1	characteristics					1021:1035	the mechanical characteristics	1006:1035	the mechanical characteristics	1006:1035	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	7	63	from	effect	945:950	arg1	absorbency					1047:1056	water absorbency	1041:1056	water absorbency	1041:1056	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	9	64	theme	hemp	1289:1292	arg1	reinforcement					1294:1306	hemp reinforcement	1289:1306	hemp reinforcement	1289:1306	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	11	65	theme	exudate	1746:1752	arg1	absorbency					1754:1763	exudate absorbency	1746:1763	exudate absorbency (p-value 0.043)	1746:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	65	theme	exudate	1746:1752	arg1	0.043					1774:1778	p-value 0.043	1766:1778	p-value 0.043	1766:1778	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	7	66	theme	mechanical	1010:1019	arg1	characteristics					1021:1035	the mechanical characteristics	1006:1035	the mechanical characteristics	1006:1035	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	9	67	theme	mechanical	1322:1331	arg1	properties					1333:1342	better mechanical properties	1315:1342	better mechanical properties	1315:1342	Both fibers' reinforcement enhanced the strength of the alginate hydrogel fiber, but hemp reinforcement showed better mechanical properties.					
37119888	4	68	theme	natural	530:536	arg1	fibers					574:579	natural fiber-reinforced composite hydrogel fibers	530:579	natural fiber-reinforced composite hydrogel fibers for wound dressing application	530:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	8	69	theme	Diclofenac	1071:1080	arg1	drug					1089:1092	Diclofenac sodium drug	1071:1092	Diclofenac sodium drug	1071:1092	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	7	70	theme	weight	988:993	arg1	percent					995:1001	fiber weight percent	982:1001	fiber weight percent	982:1001	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	6	71	theme	composite	768:776	arg1	fibers					787:792	the prepared composite hydrogel fibers	755:792	the prepared composite hydrogel fibers	755:792	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	10	72	theme	absorbency	1452:1461	arg1	strength					1395:1402	a maximum tensile strength	1377:1402	a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency	1377:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	0	73	theme	wound	119:123	arg1	dressings					125:133	wound dressings	119:133	wound dressings	119:133	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	12	74	theme	antibacterial	1901:1913	arg1	effectiveness					1915:1927	antibacterial effectiveness	1901:1927	antibacterial effectiveness	1901:1927	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	7	75	theme	alginate	955:962	arg1	concentration					964:976	alginate concentration	955:976	alginate concentration	955:976	The effect of alginate concentration and fiber weight percent on the mechanical characteristics and water absorbency was studied.					
37119888	4	76	theme	wound	585:589	arg1	application					600:610	wound dressing application	585:610	wound dressing application	585:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	3	77	theme	mechanical	448:457	arg1	properties					459:468	mechanical properties	448:468	mechanical properties	448:468	However, even if mechanical properties are enhanced, drapability remains an issue.					
37119888	6	78	theme	prepared	759:766	arg1	fibers					787:792	the prepared composite hydrogel fibers	755:792	the prepared composite hydrogel fibers	755:792	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	0	79	theme	fibers	42:47	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	0	79	theme	fibers	42:47	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	12	80	theme	drug	1876:1879	arg1	release					1881:1887	drug release	1876:1887	drug release	1876:1887	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	4	81	theme	composite	555:563	arg1	fibers					574:579	natural fiber-reinforced composite hydrogel fibers	530:579	natural fiber-reinforced composite hydrogel fibers for wound dressing application	530:610	In that regard, natural fiber-reinforced composite hydrogel fibers for wound dressing application are investigated in this study.					
37119888	11	82	theme	p-value	1701:1707	arg1	absorbency					1689:1698	exudate absorbency	1681:1698	exudate absorbency (p-value 0.020)	1681:1714	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	82	theme	p-value	1701:1707	arg1	0.020					1709:1713	p-value 0.020	1701:1713	p-value 0.020	1701:1713	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	83	theme	sodium	1611:1616	arg1	concentration					1627:1639	sodium alginate concentration	1611:1639	sodium alginate concentration	1611:1639	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	0	84	theme	alginate	60:67	arg1	fibers					78:83	alginate hydrogel fibers	60:83	alginate hydrogel fibers loaded with diclofenac sodium for wound dressings	60:133	Synthesis and characterization of natural fibers reinforced alginate hydrogel fibers loaded with diclofenac sodium for wound dressings.					
37119888	12	85	theme	improved	1830:1837	arg1	properties					1850:1859	improved mechanical properties	1830:1859	improved mechanical properties	1830:1859	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	12	86	theme	release	1881:1887	arg1	capable					1865:1871	capable	1865:1871	capable	1865:1871	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	10	87	theme	maximum	1379:1385	arg1	strength					1395:1402	a maximum tensile strength	1377:1402	a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency	1377:1461	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	2	88	theme	hydrogel	359:366	arg1	structure					368:376	the hydrogel structure	355:376	the hydrogel structure	355:376	Pure hydrogels are usually weak and brittle; therefore, reinforcements are assimilated into the hydrogel structure to improve the mechanical strength of the hydrogels.					
37119888	8	89	theme	drug	1149:1152	arg1	characteristics					1187:1201	the drug release as well as antibacterial characteristics	1145:1201	the drug release as well as antibacterial characteristics	1145:1201	Diclofenac sodium drug was loaded in the hydrogel fibers and investigated the drug release as well as antibacterial characteristics.					
37119888	6	90	theme	electron	869:876	arg1	SEM					890:892	SEM	890:892	SEM	890:892	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	6	90	theme	electron	869:876	arg1	microscopy					878:887	scanning electron microscopy	860:887	scanning electron microscopy (SEM)	860:893	The properties of the prepared composite hydrogel fibers were studied with Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and differential scanning calorimeter (DSC).					
37119888	12	91	theme	hydrogel	1809:1816	arg1	fibers					1818:1823	these composite hydrogel fibers	1793:1823	these composite hydrogel fibers with improved mechanical properties	1793:1859	Therefore, these composite hydrogel fibers with improved mechanical properties are capable of drug release and exhibit antibacterial effectiveness, making them a promising option for use as wound dressings.					
37119888	11	92	theme	concentration	1627:1639	arg1	effects					1600:1606	significant effects	1588:1606	significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043)	1588:1779	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	93	theme	tensile	1644:1650	arg1	p-value					1662:1668	p-value 0.042	1662:1674	p-value 0.042	1662:1674	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	11	93	theme	tensile	1644:1650	arg1	strength					1652:1659	tensile strength	1644:1659	tensile strength (p-value 0.042)	1644:1675	Statistical analysis revealed significant effects of sodium alginate concentration on tensile strength (p-value 0.042) and exudate absorbency (p-value 0.020) and of reinforcement (wt%) on exudate absorbency (p-value 0.043).					
37119888	5	94	used	used	671:674	arg2	reinforcement					679:691	reinforcement	679:691	reinforcement	679:691	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	5	94	used	used	671:674	arg2	fibers					659:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers	644:664	Kapok and hemp fibers were used as reinforcement to improve the strength of hydrogel fibers.					
37119888	10	95	theme	174	1407:1409	arg1	elongation					1422:1431	1.24 % elongation	1415:1431	1.24 % elongation	1415:1431	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
37119888	10	95	theme	174	1407:1409	arg1	cN					1411:1412	174 cN	1407:1412	174 cN (1.24 % elongation)	1407:1432	Kapok reinforcement resulted in a maximum tensile strength of 174 cN (1.24 % elongation) and 432 % exudate absorbency, while hemp reinforcement resulted in 185 cN (1.48 % elongation) and 435 % exudate absorbency.					
35422301	0	0	theme	ciprofloxacin	103:115	arg1	detection					90:98	selective and sensitive detection	66:98	selective and sensitive detection of ciprofloxacin	66:115	Tb-coordination polymer-anchored nanocellulose composite film for selective and sensitive detection of ciprofloxacin.					
35422301	1	1	theme	issues	245:250	arg1	one					220:222	one	220:222	one	220:222	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	1	1	theme	issues	245:250	arg1	issues					245:250	key environmental issues	227:250	key environmental issues	227:250	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	2	2	theme	room	482:485	arg1	temperature					487:497	room temperature	482:497	room temperature	482:497	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	1	3	theme	ciprofloxacin	175:187	arg1	application					160:170	the extensive application	146:170	the extensive application of ciprofloxacin (CIP)	146:193	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	4	4	theme	Tb-AMP	745:750	arg1	%					768:768	7.2%	765:768	7.2%	765:768	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	4	4	theme	Tb-AMP	745:750	arg1	ratio					736:740	the deposition ratio	721:740	the deposition ratio of Tb-AMP on TOCNF	721:759	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	4	5	from	ratio	736:740	arg1	TOCNF					755:759	TOCNF	755:759	TOCNF	755:759	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	2	6	theme	novel	277:281	arg1	film					330:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	3	7	theme	terbium	564:570	arg1	ion					572:574	terbium ion	564:574	terbium ion	564:574	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	6	8	theme	quantitative	1132:1143	arg1	analysis					1158:1165	future quantitative colorimetric analysis	1125:1165	future quantitative colorimetric analysis of pollutants	1125:1179	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	5	9	theme	Tb-AMP	920:925	arg1	TOCNF					927:931	Tb-AMP@TOCNF	920:931	Tb-AMP@TOCNF	920:931	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	10	from	concentration	1011:1023	arg1	range					1032:1036	the range	1028:1036	the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	1028:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	11	theme	1-8 μM	1041:1046	arg1	range					1032:1036	the range	1028:1036	the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	1028:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	12	theme	@	926:926	arg1	TOCNF					927:931	Tb-AMP@TOCNF	920:931	Tb-AMP@TOCNF	920:931	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	4	13	theme	environmental	778:790	arg1	good					806:809	good	806:809	good	806:809	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	4	13	theme	environmental	778:790	arg1	stability					792:800	the environmental stability	774:800	the environmental stability	774:800	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	5	14	theme	TOCNF	927:931	arg1	intensity					907:915	the fluorescence intensity	890:915	the fluorescence intensity of Tb-AMP@TOCNF	890:931	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	15	theme	composite	320:328	arg1	film					330:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	5	16	with	relationship	989:1000	arg1	concentration					1011:1023	CIP concentration	1007:1023	CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	1007:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	17	theme	CIP	1007:1009	arg1	concentration					1011:1023	CIP concentration	1007:1023	CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	1007:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	18	theme	nanocellulose	306:318	arg1	film					330:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	0	19	theme	composite	47:55	arg1	film					57:60	nanocellulose composite film	33:60	nanocellulose composite film for selective and sensitive detection of ciprofloxacin	33:115	Tb-coordination polymer-anchored nanocellulose composite film for selective and sensitive detection of ciprofloxacin.					
35422301	5	20	theme	good	977:980	arg1	relationship					989:1000	a good linear relationship	975:1000	a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	975:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	21	theme	responsive	295:304	arg1	film					330:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	0	22	theme	nanocellulose	33:45	arg1	film					57:60	nanocellulose composite film	33:60	nanocellulose composite film for selective and sensitive detection of ciprofloxacin	33:115	Tb-coordination polymer-anchored nanocellulose composite film for selective and sensitive detection of ciprofloxacin.					
35422301	6	23	theme	new	1106:1108	arg1	It					1097:1098	It	1097:1098	It	1097:1098	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	6	23	theme	new	1106:1108	arg1	way					1110:1112	a new way	1104:1112	a new way to realize future quantitative colorimetric analysis of pollutants	1104:1179	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	3	24	theme	@	642:642	arg1	TOCNF					643:647	Tb-AMP@TOCNF	636:647	Tb-AMP@TOCNF	636:647	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	2	25	theme	fluorescent	283:293	arg1	film					330:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film	275:333	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	2	26	theme	coordination	430:441	arg1	Tb-AMP					452:457	Tb-AMP	452:457	Tb-AMP	452:457	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	2	26	theme	coordination	430:441	arg1	polymer					443:449	terbium coordination polymer	422:449	terbium coordination polymer (Tb-AMP)	422:458	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	3	27	theme	TOCNF	643:647	arg1	fluorescence					620:631	the green fluorescence	610:631	the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp	610:668	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	5	28	theme	linear	982:987	arg1	relationship					989:1000	a good linear relationship	975:1000	a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	975:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	29	theme	terbium	422:428	arg1	Tb-AMP					452:457	Tb-AMP	452:457	Tb-AMP	452:457	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	2	29	theme	terbium	422:428	arg1	polymer					443:449	terbium coordination polymer	422:449	terbium coordination polymer (Tb-AMP)	422:458	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	6	30	theme	pollutants	1170:1179	arg1	analysis					1158:1165	future quantitative colorimetric analysis	1125:1165	future quantitative colorimetric analysis of pollutants	1125:1179	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	2	31	theme	aqueous	464:470	arg1	medium					472:477	aqueous medium	464:477	aqueous medium	464:477	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	4	32	theme	fluorescent	835:845	arg1	detection					847:855	fluorescent detection	835:855	fluorescent detection	835:855	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	3	33	theme	Tb-AMP	636:641	arg1	TOCNF					643:647	Tb-AMP@TOCNF	636:647	Tb-AMP@TOCNF	636:647	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	4	34	theme	Tb-AMP	695:700	arg1	TOCNF					702:706	the Tb-AMP@TOCNF	691:706	the Tb-AMP@TOCNF	691:706	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	0	35	theme	selective	66:74	arg1	detection					90:98	selective and sensitive detection	66:98	selective and sensitive detection of ciprofloxacin	66:115	Tb-coordination polymer-anchored nanocellulose composite film for selective and sensitive detection of ciprofloxacin.					
35422301	3	36	theme	UV	662:663	arg1	lamp					665:668	365 nm UV lamp	655:668	365 nm UV lamp	655:668	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	3	37	theme	antenna	584:590	arg1	effect					592:597	antenna effect	584:597	antenna effect	584:597	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	5	38	theme	CIP	861:863	arg1	concentration					865:877	CIP concentration	861:877	CIP concentration	861:877	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	39	dep	1-8 μM	1041:1046	arg1	R2 = 0.999					1067:1076	R2 = 0.999	1067:1076	R2 = 0.999	1067:1076	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	39	dep	1-8 μM	1041:1046	arg1	y = 4.57 + 3.17x					1049:1064	y = 4.57 + 3.17x	1049:1064	y = 4.57 + 3.17x	1049:1064	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	39	dep	1-8 μM	1041:1046	arg1	LOD = 0.0392 μM					1079:1093	LOD = 0.0392 μM	1079:1093	LOD = 0.0392 μM	1079:1093	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	1	40	theme	extensive	150:158	arg1	application					160:170	the extensive application	146:170	the extensive application of ciprofloxacin (CIP)	146:193	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	3	41	theme	green	614:618	arg1	fluorescence					620:631	the green fluorescence	610:631	the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp	610:668	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	4	42	theme	TOCNF	702:706	arg1	transparency					675:686	The transparency	671:686	The transparency of the Tb-AMP@TOCNF	671:706	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	4	42	theme	TOCNF	702:706	arg1	%					714:714	88%	712:714	88%	712:714	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	1	43	theme	recent	121:126	arg1	years					128:132	recent years	121:132	recent years	121:132	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	6	44	theme	colorimetric	1145:1156	arg1	analysis					1158:1165	future quantitative colorimetric analysis	1125:1165	future quantitative colorimetric analysis of pollutants	1125:1179	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	4	45	theme	deposition	725:734	arg1	%					768:768	7.2%	765:768	7.2%	765:768	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	4	45	theme	deposition	725:734	arg1	ratio					736:740	the deposition ratio	721:740	the deposition ratio of Tb-AMP on TOCNF	721:759	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	5	46	theme	fluorescence	894:905	arg1	intensity					907:915	the fluorescence intensity	890:915	the fluorescence intensity of Tb-AMP@TOCNF	890:931	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	4	47	theme	@	701:701	arg1	TOCNF					702:706	the Tb-AMP@TOCNF	691:706	the Tb-AMP@TOCNF	691:706	The transparency of the Tb-AMP@TOCNF was 88% when the deposition ratio of Tb-AMP on TOCNF was 7.2% and the environmental stability was good, which was conducive to fluorescent detection.					
35422301	5	48	contain	had	971:973	arg2	relationship					989:1000	a good linear relationship	975:1000	a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM)	975:1094	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	5	48	contain	had	971:973	arg1	intensity					961:969	fluorescence intensity	948:969	fluorescence intensity	948:969	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	49	theme	in-situ	503:509	arg1	synthesis					511:519	in-situ synthesis	503:519	in-situ synthesis	503:519	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	3	50	theme	365 nm	655:660	arg1	lamp					665:668	365 nm UV lamp	655:668	365 nm UV lamp	655:668	CIP could supply energy for terbium ion through antenna effect to achieve the green fluorescence of Tb-AMP@TOCNF under 365 nm UV lamp.					
35422301	6	51	theme	future	1125:1130	arg1	analysis					1158:1165	future quantitative colorimetric analysis	1125:1165	future quantitative colorimetric analysis of pollutants	1125:1179	It was a new way to realize future quantitative colorimetric analysis of pollutants.					
35422301	2	52	theme	cellulose	389:397	arg1	TOCNF					411:415	TOCNF	411:415	TOCNF	411:415	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	2	52	theme	cellulose	389:397	arg1	nanofibers					399:408	TEMPO-oxidized cellulose nanofibers	374:408	TEMPO-oxidized cellulose nanofibers (TOCNF)	374:416	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	1	53	theme	key	227:229	arg1	issues					245:250	key environmental issues	227:250	key environmental issues	227:250	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
35422301	0	54	theme	sensitive	80:88	arg1	detection					90:98	selective and sensitive detection	66:98	selective and sensitive detection of ciprofloxacin	66:115	Tb-coordination polymer-anchored nanocellulose composite film for selective and sensitive detection of ciprofloxacin.					
35422301	5	55	theme	fluorescence	948:959	arg1	intensity					961:969	fluorescence intensity	948:969	fluorescence intensity	948:969	As CIP concentration increased, the fluorescence intensity of Tb-AMP@TOCNF increased, and fluorescence intensity had a good linear relationship with CIP concentration in the range of 1-8 μM (y = 4.57 + 3.17x, R2 = 0.999, LOD = 0.0392 μM).					
35422301	2	56	theme	TEMPO-oxidized	374:387	arg1	TOCNF					411:415	TOCNF	411:415	TOCNF	411:415	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	2	56	theme	TEMPO-oxidized	374:387	arg1	nanofibers					399:408	TEMPO-oxidized cellulose nanofibers	374:408	TEMPO-oxidized cellulose nanofibers (TOCNF)	374:416	A novel fluorescent responsive nanocellulose composite film was successfully prepared by combining TEMPO-oxidized cellulose nanofibers (TOCNF) and terbium coordination polymer (Tb-AMP), in aqueous medium at room temperature via in-situ synthesis to detect CIP.					
35422301	1	57	theme	environmental	231:243	arg1	issues					245:250	key environmental issues	227:250	key environmental issues	227:250	In recent years, along with the extensive application of ciprofloxacin (CIP), it has gradually become one of key environmental issues to be solved urgently.					
36108577	4	0	theme	mcl-PHA	708:714	arg1	oil					739:741	mcl-PHA and epoxidized cardoon oil	708:741	mcl-PHA and epoxidized cardoon oil	708:741	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	3	1	theme	root	534:537	arg1	inulin					539:544	root inulin	534:544	root inulin	534:544	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	2	2	theme	different	285:293	arg1	components					303:312	different cardoon components	285:312	different cardoon components	285:312	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	4	3	theme	PHB	674:676	arg1	matrix					686:691	the PHB polymer matrix	670:691	the PHB polymer matrix	670:691	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	2	4	theme	high	319:322	arg1	value					330:334	high added value	319:334	high added value products	319:343	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	5	5	theme	circular	979:986	arg1	economy					988:994	circular economy	979:994	circular economy	979:994	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	4	6	theme	cardoon	731:737	arg1	oil					739:741	mcl-PHA and epoxidized cardoon oil	708:741	mcl-PHA and epoxidized cardoon oil	708:741	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	0	7	theme	biopolymers	106:116	arg1	synthesis					93:101	the synthesis	89:101	the synthesis of biopolymers and additives	89:130	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	3	8	theme	seed	550:553	arg1	oil					555:557	seed oil	550:557	seed oil respectively	550:570	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	3	9	theme	medium-chain-length	445:463	arg1	mcl-PHA					488:494	mcl-PHA	488:494	mcl-PHA	488:494	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	3	9	theme	medium-chain-length	445:463	arg1	Polyhydroxyalkanoates					465:485	medium-chain-length Polyhydroxyalkanoates	445:485	medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production	445:506	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	5	10	theme	proof-of	917:924	arg1	concept					926:932	This proof-of concept	912:932	This proof-of concept	912:932	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	3	11	theme	Polyhydroxyalkanoates	465:485	arg1	production					497:506	medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production	445:506	medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production	445:506	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	0	12	theme	cardoon	10:16	arg1	biomass					18:24	cardoon biomass	10:24	cardoon biomass	10:24	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	4	13	theme	physical	859:866	arg1	interaction					868:878	the physical interaction	855:878	the physical interaction occurring among the components	855:909	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	5	14	from	paper	945:949	arg1	approach					967:974	the holistic approach	954:974	the holistic approach of circular economy applied to bioplastic production	954:1027	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	1	15	dep	cardunculus	149:159	arg1	L.					161:162	Cynara cardunculus L.	142:162	Cynara cardunculus L.	142:162	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	1	16	theme	biorefinery	177:187	arg1	crop					189:192	a biorefinery crop	175:192	a biorefinery crop with a great potential in the bioplastic field	175:239	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	2	17	theme	upgraded	376:383	arg1	bioplastics					385:395	novel upgraded bioplastics	370:395	novel upgraded bioplastics	370:395	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	0	18	theme	additives	122:130	arg1	synthesis					93:101	the synthesis	89:101	the synthesis of biopolymers and additives	89:130	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	2	19	theme	components	303:312	arg1	valorization					269:280	the valorization	265:280	the valorization of different cardoon components into high added value products	265:343	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	4	20	theme	additives	780:788	arg1	effect					765:770	a synergic effect	754:770	a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components	754:909	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	2	21	theme	cardoon	295:301	arg1	components					303:312	different cardoon components	285:312	different cardoon components	285:312	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	0	22	theme	based	51:55	arg1	blends					57:62	Polyhydroxybutyrate based blends	31:62	Polyhydroxybutyrate based blends	31:62	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	4	23	theme	thermal	823:829	arg1	properties					831:840	PHB structural and thermal properties	804:840	PHB structural and thermal properties	804:840	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	4	24	theme	polymer	678:684	arg1	matrix					686:691	the PHB polymer matrix	670:691	the PHB polymer matrix	670:691	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	1	25	theme	great	201:205	arg1	potential					207:215	a great potential	199:215	a great potential in the bioplastic field	199:239	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	0	26	theme	Polyhydroxybutyrate	31:49	arg1	blends					57:62	Polyhydroxybutyrate based blends	31:62	Polyhydroxybutyrate based blends	31:62	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	3	27	theme	polymer	622:628	arg1	properties					630:639	polymer properties	622:639	polymer properties	622:639	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	3	28	theme	process	600:606	arg1	conditions					608:617	process conditions	600:617	process conditions	600:617	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	1	29	from	potential	207:215	arg1	field					235:239	the bioplastic field	220:239	the bioplastic field	220:239	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	4	30	theme	epoxidized	720:729	arg1	oil					739:741	mcl-PHA and epoxidized cardoon oil	708:741	mcl-PHA and epoxidized cardoon oil	708:741	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	5	31	theme	holistic	958:965	arg1	approach					967:974	the holistic approach	954:974	the holistic approach of circular economy applied to bioplastic production	954:1027	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	1	32	with	crop	189:192	arg1	potential					207:215	a great potential	199:215	a great potential in the bioplastic field	199:239	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	3	33	theme	conditions	608:617	arg1	effect					590:595	the effect	586:595	the effect of process conditions on polymer properties	586:639	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	4	34	theme	PHB	804:806	arg1	properties					831:840	PHB structural and thermal properties	804:840	PHB structural and thermal properties	804:840	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	2	35	theme	value	330:334	arg1	products					336:343	high added value products	319:343	high added value products	319:343	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	4	36	theme	synergic	756:763	arg1	effect					765:770	a synergic effect	754:770	a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components	754:909	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	5	37	theme	bioplastic	1007:1016	arg1	production					1018:1027	bioplastic production	1007:1027	bioplastic production	1007:1027	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	2	38	theme	added	324:328	arg1	value					330:334	high added value	319:334	high added value products	319:343	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	3	39	from	effect	590:595	arg1	properties					630:639	polymer properties	622:639	polymer properties	622:639	Bioprocesses for Polyhydroxybutyrate (PHB) and medium-chain-length Polyhydroxyalkanoates (mcl-PHA) production were set up starting from root inulin and seed oil respectively, highlighting the effect of process conditions on polymer properties.					
36108577	0	40	theme	holistic	67:74	arg1	approach					76:83	A holistic approach	65:83	A holistic approach for the synthesis of biopolymers and additives	65:130	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	5	41	theme	economy	988:994	arg1	approach					967:974	the holistic approach	954:974	the holistic approach of circular economy applied to bioplastic production	954:1027	This proof-of concept frames the paper in the holistic approach of circular economy applied to bioplastic production.					
36108577	4	42	theme	structural	808:817	arg1	properties					831:840	PHB structural and thermal properties	804:840	PHB structural and thermal properties	804:840	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	4	43	theme	ternary	646:652	arg1	blend					654:658	The ternary blend	642:658	The ternary blend	642:658	The ternary blend, in which the PHB polymer matrix was added with mcl-PHA and epoxidized cardoon oil, evidenced a synergic effect of both additives in modulating PHB structural and thermal properties, promoted by the physical interaction occurring among the components.					
36108577	2	44	theme	novel	370:374	arg1	bioplastics					385:395	novel upgraded bioplastics	370:395	novel upgraded bioplastics	370:395	This work investigates the valorization of different cardoon components into high added value products, finally recombined into novel upgraded bioplastics.					
36108577	1	45	theme	bioplastic	224:233	arg1	field					235:239	the bioplastic field	220:239	the bioplastic field	220:239	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	0	46	dep	Upgrading	0:8	arg1	approach					76:83	A holistic approach	65:83	A holistic approach for the synthesis of biopolymers and additives	65:130	Upgrading cardoon biomass into Polyhydroxybutyrate based blends: A holistic approach for the synthesis of biopolymers and additives.					
36108577	1	47	theme	Cynara	142:147	arg1	Cardoon					133:139	Cardoon	133:139	Cardoon	133:139	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
36108577	1	47	theme	Cynara	142:147	arg1	cardunculus					149:159	Cynara cardunculus L.	142:162	Cynara cardunculus L.	142:162	Cardoon, Cynara cardunculus L. represents a biorefinery crop with a great potential in the bioplastic field.					
37245764	0	0	theme	SCOBY/pomegranate	100:116	arg1	pigment					130:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	5	1	theme	Listeria	1184:1191	arg1	monocytogenes					1193:1205	Listeria monocytogenes	1184:1205	Listeria monocytogenes	1184:1205	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	2	dep	zone	1304:1307	arg1	to					1284:1285	to	1284:1285	to	1284:1285	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	1	3	theme	consumer	284:291	arg1	awareness					293:301	consumer awareness	284:301	consumer awareness of high-quality foods in eco-friendly packaging	284:349	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	0	4	theme	cellulose/Kombucha	81:98	arg1	pigment					130:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	5	5	dep	Gram-positive	1169:1181	arg1	aureus					1226:1231	Staphylococcus aureus	1211:1231	Staphylococcus aureus	1211:1231	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	5	dep	Gram-positive	1169:1181	arg1	monocytogenes					1193:1205	Listeria monocytogenes	1184:1205	Listeria monocytogenes	1184:1205	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	2	6	theme	cellulose	609:617	arg1	PAE					559:561	PAE	559:561	PAE	559:561	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	6	theme	cellulose	609:617	arg1	%					593:593	1-15 %	588:593	1-15 %	588:593	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	6	theme	cellulose	609:617	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	6	theme	cellulose	609:617	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	6	theme	cellulose	609:617	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	6	theme	cellulose	609:617	arg1	CMC					520:522	CMC	520:522	CMC	520:522	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	5	7	theme	Gram-negative	1091:1103	arg1	bacteria					1234:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	4	8	theme	potent	908:913	arg1	properties					927:936	potent antioxidant properties	908:936	potent antioxidant properties	908:936	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	2	9	from	composites	481:490	arg1	films					470:474	flexible films	461:474	flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	461:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	9	from	composites	481:490	arg1	SCOBY					637:641	the Kombucha SCOBY	624:641	the Kombucha SCOBY (BC Kombucha)	624:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	9	from	composites	481:490	arg1	Kombucha					647:654	BC Kombucha	644:654	BC Kombucha	644:654	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	10	theme	bacterial	599:607	arg1	cellulose					609:617	bacterial cellulose	599:617	bacterial cellulose	599:617	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	7	11	theme	CMC-PAE/BC	1438:1447	arg1	nanocomposite					1458:1470	CMC-PAE/BC Kombucha nanocomposite	1438:1470	CMC-PAE/BC Kombucha nanocomposite	1438:1470	The results illustrated that CMC-PAE/BC Kombucha nanocomposite can increase red grapes and plums' shelf lives by up to 25 days while maintaining the fruits' quality better than those left unpacked.					
37245764	3	12	theme	CMC-PAE/BC	804:813	arg1	films					824:828	CMC-PAE/BC Kombucha films	804:828	CMC-PAE/BC Kombucha films	804:828	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	0	13	theme	anthocyanin	118:128	arg1	pigment					130:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	7	14	theme	Kombucha	1449:1456	arg1	nanocomposite					1458:1470	CMC-PAE/BC Kombucha nanocomposite	1438:1470	CMC-PAE/BC Kombucha nanocomposite	1438:1470	The results illustrated that CMC-PAE/BC Kombucha nanocomposite can increase red grapes and plums' shelf lives by up to 25 days while maintaining the fruits' quality better than those left unpacked.					
37245764	1	15	theme	high-quality	306:317	arg1	foods					319:323	high-quality foods	306:323	high-quality foods	306:323	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	7	16	theme	red	1485:1487	arg1	grapes					1489:1494	red grapes	1485:1494	red grapes	1485:1494	The results illustrated that CMC-PAE/BC Kombucha nanocomposite can increase red grapes and plums' shelf lives by up to 25 days while maintaining the fruits' quality better than those left unpacked.					
37245764	4	17	theme	DDPH	835:838	arg1	test					851:854	The DDPH scavenging test	831:854	The DDPH scavenging test	831:854	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	6	18	theme	red	1387:1389	arg1	grapes					1391:1396	pack red grapes	1382:1396	pack red grapes	1382:1396	The CMC-PAE/BC Kombucha nanocomposite has additionally been utilized to pack red grapes and plums.					
37245764	2	19	theme	extract	550:556	arg1	composites					481:490	composites	481:490	composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	481:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	19	theme	extract	550:556	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	19	theme	extract	550:556	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	19	theme	extract	550:556	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	3	20	theme	films	824:828	arg1	characterization					768:783	the physicochemical characterization	748:783	the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films	748:828	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	0	21	theme	smart	14:18	arg1	film					34:37	Multifunction smart nanocomposite film	0:37	Multifunction smart nanocomposite film for food packaging	0:56	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	6	22	theme	pack	1382:1385	arg1	grapes					1391:1396	pack red grapes	1382:1396	pack red grapes	1382:1396	The CMC-PAE/BC Kombucha nanocomposite has additionally been utilized to pack red grapes and plums.					
37245764	2	23	theme	Kombucha	628:635	arg1	SCOBY					637:641	the Kombucha SCOBY	624:641	the Kombucha SCOBY (BC Kombucha)	624:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	23	theme	Kombucha	628:635	arg1	Kombucha					647:654	BC Kombucha	644:654	BC Kombucha	644:654	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	24	theme	anthocyanin	538:548	arg1	PAE					559:561	PAE	559:561	PAE	559:561	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	24	theme	anthocyanin	538:548	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	6	25	used	utilized	1370:1377	arg2	nanocomposite					1334:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite has additionally been utilized to pack red grapes and plums.					
37245764	3	26	theme	ATR-FTIR	691:698	arg1	XRD					701:703	XRD	701:703	XRD	701:703	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	0	27	theme	Multifunction	0:12	arg1	film					34:37	Multifunction smart nanocomposite film	0:37	Multifunction smart nanocomposite film for food packaging	0:56	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	1	28	theme	foods	319:323	arg1	awareness					293:301	consumer awareness	284:301	consumer awareness of high-quality foods in eco-friendly packaging	284:349	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	4	29	theme	scavenging	840:849	arg1	test					851:854	The DDPH scavenging test	831:854	The DDPH scavenging test	831:854	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	4	30	with	matrix	896:901	arg1	properties					927:936	potent antioxidant properties	908:936	potent antioxidant properties	908:936	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	2	31	theme	fractions	577:585	arg1	composites					481:490	composites	481:490	composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	481:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	31	theme	fractions	577:585	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	31	theme	fractions	577:585	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	31	theme	fractions	577:585	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	3	32	theme	Kombucha	815:822	arg1	films					824:828	CMC-PAE/BC Kombucha films	804:828	CMC-PAE/BC Kombucha films	804:828	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	1	33	theme	sustainable	224:234	arg1	processes					248:256	sustainable development processes	224:256	sustainable development processes	224:256	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	0	34	theme	nanocomposite	20:32	arg1	film					34:37	Multifunction smart nanocomposite film	0:37	Multifunction smart nanocomposite film for food packaging	0:56	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	1	35	theme	eco-friendly	328:339	arg1	packaging					341:349	eco-friendly packaging	328:349	eco-friendly packaging	328:349	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	2	36	theme	various	569:575	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	36	theme	various	569:575	arg1	%					593:593	1-15 %	588:593	1-15 %	588:593	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	4	37	theme	antioxidant	915:925	arg1	properties					927:936	potent antioxidant properties	908:936	potent antioxidant properties	908:936	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	1	38	theme	Active	139:144	arg1	systems					154:160	Active packing systems	139:160	Active packing systems employed to preserve food quality	139:194	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	1	39	theme	development	236:246	arg1	processes					248:256	sustainable development processes	224:256	sustainable development processes	224:256	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	0	40	theme	food	43:46	arg1	packaging					48:56	food packaging	43:56	food packaging	43:56	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	5	41	theme	inhibition	1293:1302	arg1	zone					1304:1307	a 20 to 30 mm inhibition zone	1279:1307	a 20 to 30 mm inhibition zone	1279:1307	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	6	42	theme	Kombucha	1325:1332	arg1	nanocomposite					1334:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite has additionally been utilized to pack red grapes and plums.					
37245764	5	43	theme	many	1075:1078	arg1	bacteria					1234:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	44	theme	fabricated	995:1004	arg1	films					1006:1010	The fabricated films	991:1010	The fabricated films of CMC-PAE/BC Kombucha	991:1033	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	1	45	theme	processes	248:256	arg1	chains					214:219	chains	214:219	chains of sustainable development processes	214:256	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	4	46	theme	composite	974:982	arg1	films					984:988	composite films	974:988	composite films	974:988	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	3	47	theme	physicochemical	752:766	arg1	characterization					768:783	the physicochemical characterization	748:783	the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films	748:828	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	1	48	from	awareness	293:301	arg1	packaging					341:349	eco-friendly packaging	328:349	eco-friendly packaging	328:349	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	5	49	theme	pathogenic	1080:1089	arg1	bacteria					1234:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	2	50	theme	cellulose	509:517	arg1	composites					481:490	composites	481:490	composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	481:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	50	theme	cellulose	509:517	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	50	theme	cellulose	509:517	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	50	theme	cellulose	509:517	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	1	51	from	growth	274:279	arg1	awareness					293:301	consumer awareness	284:301	consumer awareness of high-quality foods in eco-friendly packaging	284:349	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	3	52	used	utilized	724:731	arg2	TEM					715:717	TEM	715:717	TEM	715:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	52	used	utilized	724:731	arg2	TGA					706:708	TGA	706:708	TGA	706:708	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	52	used	utilized	724:731	arg2	tools					677:681	Various analytical tools	658:681	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM	658:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	52	used	utilized	724:731	arg2	XRD					701:703	XRD	701:703	XRD	701:703	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	1	53	theme	packing	146:152	arg1	systems					154:160	Active packing systems	139:160	Active packing systems employed to preserve food quality	139:194	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	2	54	theme	carboxymethyl	495:507	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	54	theme	carboxymethyl	495:507	arg1	CMC					520:522	CMC	520:522	CMC	520:522	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	4	55	theme	PAE	887:889	arg1	matrix					896:901	a matrix	894:901	a matrix with potent antioxidant properties	894:936	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	4	55	theme	PAE	887:889	arg1	efficiency					873:882	the efficiency	869:882	the efficiency of PAE	869:889	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	5	56	theme	Kombucha	1026:1033	arg1	films					1006:1010	The fabricated films	991:1010	The fabricated films of CMC-PAE/BC Kombucha	991:1033	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	57	theme	CMC-PAE/BC	1015:1024	arg1	Kombucha					1026:1033	CMC-PAE/BC Kombucha	1015:1033	CMC-PAE/BC Kombucha	1015:1033	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	58	dep	bacteria	1234:1241	arg1	aeruginosa					1118:1127	Pseudomonas aeruginosa	1106:1127	Pseudomonas aeruginosa	1106:1127	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	58	dep	bacteria	1234:1241	arg1	sp.					1141:1143	Salmonella sp.	1130:1143	Salmonella sp.	1130:1143	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	5	58	dep	bacteria	1234:1241	arg1	coli					1162:1165	Escherichia coli	1150:1165	Escherichia coli	1150:1165	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	2	59	from	SCOBY	637:641	arg1	PAE					559:561	PAE	559:561	PAE	559:561	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	composites					481:490	composites	481:490	composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	481:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	%					593:593	1-15 %	588:593	1-15 %	588:593	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	cellulose					509:517	carboxymethyl cellulose	495:517	carboxymethyl cellulose (CMC)	495:523	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	fractions					577:585	various fractions	569:585	various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	569:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	59	from	SCOBY	637:641	arg1	CMC					520:522	CMC	520:522	CMC	520:522	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	7	60	theme	shelf	1507:1511	arg1	lives					1513:1517	red grapes and plums' shelf lives	1485:1517	red grapes and plums' shelf lives	1485:1517	The results illustrated that CMC-PAE/BC Kombucha nanocomposite can increase red grapes and plums' shelf lives by up to 25 days while maintaining the fruits' quality better than those left unpacked.					
37245764	6	61	theme	CMC-PAE/BC	1314:1323	arg1	nanocomposite					1334:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite	1310:1346	The CMC-PAE/BC Kombucha nanocomposite has additionally been utilized to pack red grapes and plums.					
37245764	3	62	theme	Kombucha	791:798	arg1	characterization					768:783	the physicochemical characterization	748:783	the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films	748:828	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	4	63	dep	matrix	896:901	arg1	both					939:942	both	939:942	both	939:942	The DDPH scavenging test demonstrated the efficiency of PAE as a matrix with potent antioxidant properties, both as a solution and enclosed in composite films.					
37245764	3	64	theme	Various	658:664	arg1	TGA					706:708	TGA	706:708	TGA	706:708	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	64	theme	Various	658:664	arg1	TEM					715:717	TEM	715:717	TEM	715:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	64	theme	Various	658:664	arg1	XRD					701:703	XRD	701:703	XRD	701:703	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	64	theme	Various	658:664	arg1	tools					677:681	Various analytical tools	658:681	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM	658:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	2	65	theme	study	371:375	arg1	aims					377:380	this study aims	366:380	this study aims	366:380	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	5	66	theme	antimicrobial	1042:1054	arg1	activities					1056:1065	antimicrobial activities	1042:1065	antimicrobial activities	1042:1065	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	0	67	theme	carboxymethyl	67:79	arg1	pigment					130:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment	67:136	Multifunction smart nanocomposite film for food packaging based on carboxymethyl cellulose/Kombucha SCOBY/pomegranate anthocyanin pigment.					
37245764	3	68	theme	analytical	666:675	arg1	TGA					706:708	TGA	706:708	TGA	706:708	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	68	theme	analytical	666:675	arg1	TEM					715:717	TEM	715:717	TEM	715:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	68	theme	analytical	666:675	arg1	XRD					701:703	XRD	701:703	XRD	701:703	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	3	68	theme	analytical	666:675	arg1	tools					677:681	Various analytical tools	658:681	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM	658:717	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37245764	2	69	theme	flexible	461:468	arg1	films					470:474	flexible films	461:474	flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha)	461:655	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	5	70	theme	Gram-positive	1169:1181	arg1	bacteria					1234:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria	1169:1241	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	7	71	theme	better	1574:1579	arg1	quality					1566:1572	the fruits' quality	1554:1572	the fruits' quality better than those left unpacked	1554:1604	The results illustrated that CMC-PAE/BC Kombucha nanocomposite can increase red grapes and plums' shelf lives by up to 25 days while maintaining the fruits' quality better than those left unpacked.					
37245764	2	72	theme	pomegranate	526:536	arg1	PAE					559:561	PAE	559:561	PAE	559:561	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	2	72	theme	pomegranate	526:536	arg1	extract					550:556	pomegranate anthocyanin extract	526:556	pomegranate anthocyanin extract (PAE)	526:562	Consequently, this study aims to develop antioxidant, antimicrobial, UV-shielding, pH-sensitive, edible, and flexible films from composites of carboxymethyl cellulose (CMC), pomegranate anthocyanin extract (PAE), and various fractions (1-15 %) of bacterial cellulose from the Kombucha SCOBY (BC Kombucha).					
37245764	5	73	theme	Candida	1248:1254	arg1	albicans					1256:1263	Candida albicans	1248:1263	Candida albicans	1248:1263	The fabricated films of CMC-PAE/BC Kombucha showed antimicrobial activities against many pathogenic Gram-negative (Pseudomonas aeruginosa, Salmonella sp., and Escherichia coli), Gram-positive (Listeria monocytogenes and Staphylococcus aureus) bacteria, and Candida albicans, ranging from a 20 to 30 mm inhibition zone.					
37245764	1	74	theme	food	183:186	arg1	quality					188:194	food quality	183:194	food quality	183:194	Active packing systems employed to preserve food quality have gone through chains of sustainable development processes, reflecting the growth in consumer awareness of high-quality foods in eco-friendly packaging.					
37245764	3	75	theme	BC	788:789	arg1	Kombucha					791:798	BC Kombucha	788:798	BC Kombucha	788:798	Various analytical tools such as ATR-FTIR, XRD, TGA, and TEM were utilized to investigate the physicochemical characterization of BC Kombucha and CMC-PAE/BC Kombucha films.					
37087268	0	0	theme	roasted	88:94	arg1	beans					103:107	roasted coffee beans	88:107	roasted coffee beans	88:107	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	2	1	from	acid	456:459	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	4	2	theme	cryptochlorogenic	854:870	arg1	acid					872:875	cryptochlorogenic acid	854:875	cryptochlorogenic acid	854:875	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	3	theme	total	888:892	arg1	TPC					905:907	TPC	905:907	TPC	905:907	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	3	theme	total	888:892	arg1	phenolics					894:902	total phenolics	888:902	total phenolics (TPC)	888:908	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	1	4	theme	coffee	162:167	arg1	beans					169:173	green coffee beans	156:173	green coffee beans	156:173	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	3	5	theme	green	717:721	arg1	beans					723:727	green beans	717:727	green beans	717:727	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	6	located	found	708:712	arg2	correlations					578:589	significant positive correlations	557:589	significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine	557:702	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	6	located	found	708:712	arg1	beans					723:727	green beans	717:727	green beans	717:727	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	1	7	theme	beans	169:173	arg1	compositions					140:151	chemical compositions	131:151	chemical compositions of green coffee beans	131:173	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	5	8	theme	beans	1188:1192	arg1	selection					1161:1169	the selection	1157:1169	the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks	1157:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	4	9	theme	flavonoids	920:929	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	9	theme	flavonoids	920:929	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	10	from	phenylalanine	462:474	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	11	theme	coffee	1181:1186	arg1	beans					1188:1192	proper coffee beans	1174:1192	proper coffee beans	1174:1192	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	3	12	theme	significant	557:567	arg1	correlations					578:589	significant positive correlations	557:589	significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine	557:702	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	5	13	theme	valuable	1130:1137	arg1	enlightenment					1139:1151	valuable enlightenment	1130:1151	valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks	1130:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	0	14	theme	coffee	96:101	arg1	beans					103:107	roasted coffee beans	88:107	roasted coffee beans	88:107	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	2	15	from	acid	486:489	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	4	16	theme	acid	872:875	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	16	theme	acid	872:875	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	3	17	theme	positive	569:576	arg1	correlations					578:589	significant positive correlations	557:589	significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine	557:702	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	5	18	theme	chemical	1247:1254	arg1	risks					1266:1270	low chemical hazardous risks	1243:1270	low chemical hazardous risks	1243:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	2	19	theme	coffee	533:538	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	0	20	from	components	49:58	arg1	beans					103:107	roasted coffee beans	88:107	roasted coffee beans	88:107	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	4	21	theme	slight	988:993	arg1	relationships					1004:1016	slight negative relationships	988:1016	slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC	988:1107	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	22	theme	chlorogenic	1063:1073	arg1	acid					1075:1078	chlorogenic acid	1063:1078	chlorogenic acid	1063:1078	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	23	theme	green	527:531	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	24	with	production	1198:1207	arg1	risks					1266:1270	low chemical hazardous risks	1243:1270	low chemical hazardous risks	1243:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	5	24	with	production	1198:1207	arg1	nutrition					1229:1237	high nutrition	1224:1237	high nutrition	1224:1237	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	2	25	theme	linolenic	492:500	arg1	acid					502:505	linolenic acid	492:505	linolenic acid	492:505	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	2	25	theme	linolenic	492:500	arg1	lipid					431:435	lipid	431:435	lipid	431:435	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	4	26	with	acids	966:970	arg1	active					813:818	active	813:818	active	813:818	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	27	theme	statistical	301:311	arg1	techniques					313:322	multivariate statistical techniques	288:322	multivariate statistical techniques	288:322	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	1	28	theme	multi-production	180:195	arg1	regions					197:203	multi-production regions	180:203	multi-production regions	180:203	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	3	29	with	correlations	578:589	arg1	alanine					650:656	alanine	650:656	alanine	650:656	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	histidine					659:667	histidine	659:667	histidine	659:667	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	caffeine					695:702	caffeine	695:702	caffeine	695:702	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	acid					636:639	aspartic acid	627:639	aspartic acid	627:639	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	serine					642:647	serine	642:647	serine	642:647	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	asparagine					670:679	asparagine	670:679	asparagine	670:679	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	3	29	with	correlations	578:589	arg1	protein					682:688	protein	682:688	protein	682:688	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	4	30	theme	acid	848:851	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	30	theme	acid	848:851	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	3	31	theme	acrylamide	599:608	arg1	levels					615:620	acrylamide (AA) levels	599:620	acrylamide (AA) levels	599:620	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	4	32	theme	neochlorogenic	833:846	arg1	acid					848:851	neochlorogenic acid	833:851	neochlorogenic acid	833:851	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	33	theme	palmitic	1048:1055	arg1	acid					1057:1060	palmitic acid	1048:1060	palmitic acid	1048:1060	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	0	34	theme	green	31:35	arg1	components					49:58	green coffee bean components	31:58	green coffee bean components	31:58	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	4	35	theme	furan	751:755	arg1	5-HMF					744:748	5-HMF	744:748	5-HMF	744:748	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	36	theme	several	952:958	arg1	acids					966:970	several amino acids	952:970	several amino acids	952:970	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	37	theme	5-hydroxymethylfurfural	338:360	arg1	formation					325:333	formation	325:333	formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran	325:397	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	2	38	theme	glutamic	447:454	arg1	acid					456:459	glutamic acid	447:459	glutamic acid	447:459	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	2	38	theme	glutamic	447:454	arg1	lipid					431:435	lipid	431:435	lipid	431:435	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	2	39	theme	2-	378:379	arg1	formation					325:333	formation	325:333	formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran	325:397	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	40	theme	high	1224:1227	arg1	nutrition					1229:1237	high nutrition	1224:1237	high nutrition	1224:1237	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	0	41	theme	bean	44:47	arg1	components					49:58	green coffee bean components	31:58	green coffee bean components	31:58	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	5	42	theme	hazardous	1256:1264	arg1	risks					1266:1270	low chemical hazardous risks	1243:1270	low chemical hazardous risks	1243:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	4	43	theme	total	914:918	arg1	flavonoids					920:929	total flavonoids	914:929	total flavonoids	914:929	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	44	from	acid	502:505	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	45	theme	low	1243:1245	arg1	risks					1266:1270	low chemical hazardous risks	1243:1270	low chemical hazardous risks	1243:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	0	46	theme	coffee	37:42	arg1	components					49:58	green coffee bean components	31:58	green coffee bean components	31:58	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	4	47	theme	amino	960:964	arg1	acids					966:970	several amino acids	952:970	several amino acids	952:970	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	0	48	from	contaminants	72:83	arg1	beans					103:107	roasted coffee beans	88:107	roasted coffee beans	88:107	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	4	49	theme	negative	786:793	arg1	correlations					795:806	negative correlations	786:806	negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC))	786:945	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	50	from	trigonelline	511:522	arg1	beans					540:544	green coffee beans	527:544	green coffee beans	527:544	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	51	theme	proper	1174:1179	arg1	beans					1188:1192	proper coffee beans	1174:1192	proper coffee beans	1174:1192	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	2	52	theme	margaric	477:484	arg1	acid					486:489	margaric acid	477:489	margaric acid	477:489	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	2	52	theme	margaric	477:484	arg1	lipid					431:435	lipid	431:435	lipid	431:435	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	4	53	theme	caffeine	878:885	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	53	theme	caffeine	878:885	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	54	theme	furan	371:375	arg1	formation					325:333	formation	325:333	formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran	325:397	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	4	55	theme	phenolics	894:902	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	55	theme	phenolics	894:902	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	2	56	theme	multivariate	288:299	arg1	techniques					313:322	multivariate statistical techniques	288:322	multivariate statistical techniques	288:322	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	1	57	theme	chemical	131:138	arg1	compositions					140:151	chemical compositions	131:151	chemical compositions of green coffee beans	131:173	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	1	58	theme	thermal	242:248	arg1	contaminants					250:261	thermal contaminants	242:261	thermal contaminants in roasted coffee	242:279	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	1	59	from	contaminants	250:261	arg1	coffee					274:279	roasted coffee	266:279	roasted coffee	266:279	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	2	60	theme	3-methylfuran	385:397	arg1	formation					325:333	formation	325:333	formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran	325:397	Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans.					
37087268	5	61	theme	coffee	1212:1217	arg1	production					1198:1207	production	1198:1207	production of coffee with high nutrition and low chemical hazardous risks	1198:1270	This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.					
37087268	3	62	theme	aspartic	627:634	arg1	acid					636:639	aspartic acid	627:639	aspartic acid	627:639	Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans.					
37087268	4	63	dep	active	813:818	arg1	contents					931:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents	833:938	neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)	833:944	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	63	dep	active	813:818	arg1	constitutes					820:830	constitutes	820:830	constitutes	820:830	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	63	dep	active	813:818	arg1	TFC					941:943	TFC	941:943	TFC	941:943	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	64	theme	myristic	1033:1040	arg1	acid					1042:1045	myristic acid	1033:1045	myristic acid	1033:1045	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	4	65	with	correlations	795:806	arg1	active					813:818	active	813:818	active	813:818	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	0	66	theme	thermal	64:70	arg1	contaminants					72:83	thermal contaminants	64:83	thermal contaminants in roasted coffee beans	64:107	Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans.					
37087268	1	67	theme	green	156:160	arg1	beans					169:173	green coffee beans	156:173	green coffee beans	156:173	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37087268	4	68	theme	negative	995:1002	arg1	relationships					1004:1016	slight negative relationships	988:1016	slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC	988:1107	Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC.					
37087268	1	69	theme	roasted	266:272	arg1	coffee					274:279	roasted coffee	266:279	roasted coffee	266:279	This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee.					
37245305	0	0	theme	zygomycetes	70:80	arg1	growth					60:65	the growth	56:65	the growth of zygomycetes	56:80	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	7	1	theme	Rhizopus	937:944	arg1	oryzae					946:951	Rhizopus oryzae	937:951	Rhizopus oryzae	937:951	Biomass and chitosan yield for Rhizopus oryzae were found 1.53 g/L; 239 mg/L.					
37245305	2	2	theme	prepared	343:350	arg1	hydrolysate					360:370	prepared protein hydrolysate	343:370	prepared protein hydrolysate	343:370	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	7	3	theme	chitosan	918:925	arg1	yield					927:931	Biomass and chitosan yield	906:931	Biomass and chitosan yield for Rhizopus oryzae	906:951	Biomass and chitosan yield for Rhizopus oryzae were found 1.53 g/L; 239 mg/L.					
37245305	4	4	theme	fermentative	734:745	arg1	growth					747:752	the fermentative growth	730:752	the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	730:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	9	5	theme	leather	1123:1129	arg1	processing					1131:1140	leather processing	1123:1140	leather processing	1123:1140	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	4	6	theme	%	610:610	arg1	extract					618:624	0.3% Yeast extract	607:624	0.3% Yeast extract	607:624	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	7	theme	nutrient	705:712	arg1	composition					714:724	the most efficient nutrient composition	686:724	the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	686:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	7	theme	nutrient	705:712	arg1	combination					592:602	A combination	590:602	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose	590:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	3	8	theme	standard	561:568	arg1	product					581:587	the standard commercial product	557:587	the standard commercial product	557:587	DLS and MALDI-TOF-MS spectra indicated that the prepared protein hydrolysate is mostly comprised of di- and tri-peptides and less poly-dispersed than the standard commercial product.					
37245305	7	9	theme	Biomass	906:912	arg1	yield					927:931	Biomass and chitosan yield	906:931	Biomass and chitosan yield for Rhizopus oryzae	906:951	Biomass and chitosan yield for Rhizopus oryzae were found 1.53 g/L; 239 mg/L.					
37245305	2	10	theme	UV-Vis	281:286	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	1	11	theme	leather	261:267	arg1	processing					269:278	leather processing	261:278	leather processing	261:278	A simple scalable method has been developed to obtain protein hydrolysate from fleshing waste generated during leather processing.					
37245305	5	12	theme	Mucor	821:825	arg1	sp					827:828	Mucor sp	821:828	Mucor sp.	821:829	Mucor sp.					
37245305	4	13	theme	0.3	607:609	arg1	%					610:610	%	610:610	%	610:610	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	1	14	theme	simple	152:157	arg1	method					168:173	A simple scalable method	150:173	A simple scalable method	150:173	A simple scalable method has been developed to obtain protein hydrolysate from fleshing waste generated during leather processing.					
37245305	0	15	theme	new	85:87	arg1	substrate					89:97	A new substrate	83:97	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.	0:148	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	2	16	theme	collagen	385:392	arg1	hydrolysate					394:404	collagen hydrolysate	385:404	collagen hydrolysate	385:404	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	6	17	theme	biomass	855:861	arg1	2.74 g/L					864:871	2.74 g/L	864:871	2.74 g/L	864:871	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	6	17	theme	biomass	855:861	arg1	yield					846:850	highest yield	838:850	highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L)	838:903	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	6	17	theme	biomass	855:861	arg1	335 mg/L					895:902	335 mg/L	895:902	335 mg/L	895:902	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	6	17	theme	biomass	855:861	arg1	chitosan					885:892	chitosan	885:892	highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L)	838:903	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	2	18	theme	State	304:308	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	7	19	dep	239 mg/L	974:981	arg1	1.53 g/L					964:971	1.53 g/L	964:971	1.53 g/L	964:971	Biomass and chitosan yield for Rhizopus oryzae were found 1.53 g/L; 239 mg/L.					
37245305	4	20	theme	2	660:660	arg1	%					661:661	%	661:661	%	661:661	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	2	21	theme	Solid	298:302	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	0	22	theme	waste	24:28	arg1	Utilization					0:10	Utilization	0:10	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.	0:148	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	4	23	theme	efficient	695:703	arg1	composition					714:724	the most efficient nutrient composition	686:724	the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	686:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	23	theme	efficient	695:703	arg1	combination					592:602	A combination	590:602	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose	590:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	0	24	theme	economical	103:112	arg1	production					114:123	economical production	103:123	economical production of bio-polymer chitosan	103:147	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	9	25	theme	low-cost	1150:1157	arg1	production					1159:1168	the low-cost production	1146:1168	the low-cost production of industrially important biopolymer chitosan	1146:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	3	26	theme	commercial	570:579	arg1	product					581:587	the standard commercial product	557:587	the standard commercial product	557:587	DLS and MALDI-TOF-MS spectra indicated that the prepared protein hydrolysate is mostly comprised of di- and tri-peptides and less poly-dispersed than the standard commercial product.					
37245305	9	27	theme	processing	1131:1140	arg1	utilization					1090:1100	utilization	1090:1100	utilization of fleshing waste of leather processing	1090:1140	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	4	28	theme	Protein	630:636	arg1	Hydrolysate					638:648	1% Protein Hydrolysate	627:648	1% Protein Hydrolysate (PHz)	627:654	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	28	theme	Protein	630:636	arg1	PHz					651:653	PHz	651:653	PHz	651:653	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	0	29	theme	fleshing	15:22	arg1	waste					24:28	fleshing waste	15:28	fleshing waste of leather processing	15:50	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	4	30	theme	extract	618:624	arg1	composition					714:724	the most efficient nutrient composition	686:724	the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	686:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	30	theme	extract	618:624	arg1	combination					592:602	A combination	590:602	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose	590:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	9	31	theme	biopolymer	1196:1205	arg1	chitosan					1207:1214	industrially important biopolymer chitosan	1173:1214	industrially important biopolymer chitosan	1173:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	2	32	theme	FTIR	289:292	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	4	33	theme	%	628:628	arg1	Hydrolysate					638:648	1% Protein Hydrolysate	627:648	1% Protein Hydrolysate (PHz)	627:654	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	33	theme	%	628:628	arg1	PHz					651:653	PHz	651:653	PHz	651:653	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	0	34	theme	leather	33:39	arg1	processing					41:50	leather processing	33:50	leather processing	33:50	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	9	35	theme	chitosan	1207:1214	arg1	production					1159:1168	the low-cost production	1146:1168	the low-cost production of industrially important biopolymer chitosan	1146:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	9	36	theme	promising	1068:1076	arg1	prospect					1078:1085	promising prospect	1068:1085	promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan	1068:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	3	37	theme	prepared	455:462	arg1	hydrolysate					472:482	the prepared protein hydrolysate	451:482	the prepared protein hydrolysate	451:482	DLS and MALDI-TOF-MS spectra indicated that the prepared protein hydrolysate is mostly comprised of di- and tri-peptides and less poly-dispersed than the standard commercial product.					
37245305	3	38	theme	MALDI-TOF-MS	415:426	arg1	spectra					428:434	MALDI-TOF-MS spectra	415:434	MALDI-TOF-MS spectra	415:434	DLS and MALDI-TOF-MS spectra indicated that the prepared protein hydrolysate is mostly comprised of di- and tri-peptides and less poly-dispersed than the standard commercial product.					
37245305	4	39	dep	zygomycetes	793:803	arg1	group					805:809	group	805:809	three well-known chitosan producing zygomycetes group of fungi	757:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	39	dep	zygomycetes	793:803	arg1	fungi					814:818	fungi	814:818	fungi	814:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	6	40	theme	highest	838:844	arg1	2.74 g/L					864:871	2.74 g/L	864:871	2.74 g/L	864:871	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	6	40	theme	highest	838:844	arg1	yield					846:850	highest yield	838:850	highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L)	838:903	showed highest yield of biomass (2.74 g/L) as well as chitosan (335 mg/L).					
37245305	4	41	theme	zygomycetes	793:803	arg1	growth					747:752	the fermentative growth	730:752	the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	730:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	3	42	theme	protein	464:470	arg1	hydrolysate					472:482	the prepared protein hydrolysate	451:482	the prepared protein hydrolysate	451:482	DLS and MALDI-TOF-MS spectra indicated that the prepared protein hydrolysate is mostly comprised of di- and tri-peptides and less poly-dispersed than the standard commercial product.					
37245305	0	43	theme	chitosan	140:147	arg1	production					114:123	economical production	103:123	economical production of bio-polymer chitosan	103:147	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	4	44	theme	fungi	814:818	arg1	group					805:809	group	805:809	three well-known chitosan producing zygomycetes group of fungi	757:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	44	theme	fungi	814:818	arg1	fungi					814:818	fungi	814:818	fungi	814:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	9	45	theme	important	1186:1194	arg1	chitosan					1207:1214	industrially important biopolymer chitosan	1173:1214	industrially important biopolymer chitosan	1173:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	0	46	theme	processing	41:50	arg1	waste					24:28	fleshing waste	15:28	fleshing waste of leather processing	15:50	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	0	47	theme	bio-polymer	128:138	arg1	chitosan					140:147	bio-polymer chitosan	128:147	bio-polymer chitosan	128:147	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	9	48	theme	utilization	1090:1100	arg1	prospect					1078:1085	promising prospect	1068:1085	promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan	1068:1214	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	4	49	theme	chitosan	774:781	arg1	zygomycetes					793:803	three well-known chitosan producing zygomycetes	757:803	three well-known chitosan producing zygomycetes group of fungi	757:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	50	theme	well-known	763:772	arg1	zygomycetes					793:803	three well-known chitosan producing zygomycetes	757:803	three well-known chitosan producing zygomycetes group of fungi	757:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	51	theme	%	661:661	arg1	Glucose					663:669	2% Glucose	660:669	2% Glucose	660:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	2	52	theme	NMR	314:316	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	1	53	theme	protein	204:210	arg1	hydrolysate					212:222	protein hydrolysate	204:222	protein hydrolysate	204:222	A simple scalable method has been developed to obtain protein hydrolysate from fleshing waste generated during leather processing.					
37245305	9	54	theme	fleshing	1105:1112	arg1	waste					1114:1118	fleshing waste	1105:1118	fleshing waste	1105:1118	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	2	55	theme	C13	310:312	arg1	analyses					318:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses	281:325	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
37245305	4	56	theme	Yeast	612:616	arg1	extract					618:624	0.3% Yeast extract	607:624	0.3% Yeast extract	607:624	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	57	theme	Hydrolysate	638:648	arg1	composition					714:724	the most efficient nutrient composition	686:724	the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	686:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	57	theme	Hydrolysate	638:648	arg1	combination					592:602	A combination	590:602	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose	590:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	58	theme	producing	783:791	arg1	zygomycetes					793:803	three well-known chitosan producing zygomycetes	757:803	three well-known chitosan producing zygomycetes group of fungi	757:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	9	59	theme	waste	1114:1118	arg1	utilization					1090:1100	utilization	1090:1100	utilization of fleshing waste of leather processing	1090:1140	This work shows promising prospect of utilization of fleshing waste of leather processing for the low-cost production of industrially important biopolymer chitosan.					
37245305	4	60	theme	Glucose	663:669	arg1	composition					714:724	the most efficient nutrient composition	686:724	the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi	686:818	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	4	60	theme	Glucose	663:669	arg1	combination					592:602	A combination	590:602	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose	590:669	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	1	61	theme	scalable	159:166	arg1	method					168:173	A simple scalable method	150:173	A simple scalable method	150:173	A simple scalable method has been developed to obtain protein hydrolysate from fleshing waste generated during leather processing.					
37245305	4	62	theme	1	627:627	arg1	%					628:628	%	628:628	%	628:628	A combination of 0.3% Yeast extract, 1% Protein Hydrolysate (PHz) and 2% Glucose is found to be the most efficient nutrient composition for the fermentative growth of three well-known chitosan producing zygomycetes group of fungi.					
37245305	0	63	dep	Utilization	0:10	arg1	substrate					89:97	A new substrate	83:97	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.	0:148	Utilization of fleshing waste of leather processing for the growth of zygomycetes: A new substrate for economical production of bio-polymer chitosan.					
37245305	2	64	theme	protein	352:358	arg1	hydrolysate					360:370	prepared protein hydrolysate	343:370	prepared protein hydrolysate	343:370	UV-Vis, FTIR and Solid State C13 NMR analyses identified that prepared protein hydrolysate is basically collagen hydrolysate.					
36244531	0	0	theme	nanofibril-based	88:103	arg1	foams					105:109	cellulose nanofibril-based foams	78:109	cellulose nanofibril-based foams for thermal energy storage	78:136	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	1	1	theme	inferior	161:168	arg1	conduction					175:184	inferior heat conduction	161:184	inferior heat conduction of organic phase change materials	161:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	8	2	theme	Novel	1361:1365	arg1	structures					1380:1389	53.4 °C. Novel PCM sandwich structures	1352:1389	53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1352:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	0	3	theme	cellulose	78:86	arg1	foams					105:109	cellulose nanofibril-based foams	78:109	cellulose nanofibril-based foams for thermal energy storage	78:136	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	8	4	theme	thermoelectric	1427:1440	arg1	generator					1442:1450	a thermoelectric generator	1425:1450	a thermoelectric generator	1425:1450	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	1	5	theme	heat	170:173	arg1	conduction					175:184	inferior heat conduction	161:184	inferior heat conduction of organic phase change materials	161:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	8	6	theme	change	1293:1298	arg1	enthalpy					1300:1307	a phase change enthalpy	1285:1307	a phase change enthalpy of 184 kJ/kg	1285:1320	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	8	7	theme	melting	1329:1335	arg1	temperature					1337:1347	a melting temperature	1327:1347	a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1327:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	5	8	theme	porous	742:747	arg1	structure					754:762	The highly porous foam structure	731:762	The highly porous foam structure	731:762	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	5	9	theme	PCM	880:882	arg1	leakage					884:890	negligible PCM leakage	869:890	negligible PCM leakage (<2 %)	869:897	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	5	9	theme	PCM	880:882	arg1	%					896:896	<2 %	893:896	<2 %	893:896	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	7	10	theme	thermal	1106:1112	arg1	stability					1114:1122	improved thermal stability	1097:1122	improved thermal stability	1097:1122	Meanwhile, the composite PCMs exhibited improved thermal stability over the control.					
36244531	8	11	theme	Pw-based	1252:1259	arg1	PCM					1271:1273	Pw-based composite PCM	1252:1273	Pw-based composite PCM	1252:1273	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	4	12	theme	chemical	625:632	arg1	modifications					634:646	Selective chemical modifications	615:646	Selective chemical modifications of nanocellulose foams	615:669	Selective chemical modifications of nanocellulose foams enhanced their shape-stability and compatibility with PCMs.					
36244531	2	13	theme	-based	308:313	arg1	foams					315:319	cellulose nanofibril (CNF)-based foams	282:319	cellulose nanofibril (CNF)-based foams	282:319	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	13	theme	-based	308:313	arg1	scaffolds					349:357	the porous scaffolds	338:357	the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage	338:434	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	0	14	theme	energy	123:128	arg1	storage					130:136	thermal energy storage	115:136	thermal energy storage	115:136	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	7	15	theme	composite	1072:1080	arg1	Meanwhile					1057:1065	Meanwhile	1057:1065	Meanwhile	1057:1065	Meanwhile, the composite PCMs exhibited improved thermal stability over the control.					
36244531	7	15	theme	composite	1072:1080	arg1	PCMs					1082:1085	the composite PCMs	1068:1085	the composite PCMs	1068:1085	Meanwhile, the composite PCMs exhibited improved thermal stability over the control.					
36244531	6	16	theme	improved	973:980	arg1	conductivities					990:1003	the improved thermal conductivities	969:1003	the improved thermal conductivities	969:1003	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	8	17	theme	change	1184:1189	arg1	enthalpy					1191:1198	a phase change enthalpy	1176:1198	a phase change enthalpy of 143 kJ/kg	1176:1211	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	1	18	theme	organic	189:195	arg1	materials					210:218	organic phase change materials	189:218	organic phase change materials	189:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	1	19	theme	conduction	175:184	arg1	PCMs					221:224	The leakage issue and inferior heat conduction of organic phase change materials (PCMs)	139:225	The leakage issue and inferior heat conduction of organic phase change materials (PCMs)	139:225	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	0	20	theme	thermal	115:121	arg1	storage					130:136	thermal energy storage	115:136	thermal energy storage	115:136	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	2	21	theme	present	267:273	arg1	study					275:279	the present study	263:279	the present study	263:279	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	6	22	theme	thermal	982:988	arg1	conductivities					990:1003	the improved thermal conductivities	969:1003	the improved thermal conductivities	969:1003	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	7	23	theme	improved	1097:1104	arg1	stability					1114:1122	improved thermal stability	1097:1122	improved thermal stability	1097:1122	Meanwhile, the composite PCMs exhibited improved thermal stability over the control.					
36244531	8	24	theme	phase	1287:1291	arg1	enthalpy					1300:1307	a phase change enthalpy	1285:1307	a phase change enthalpy of 184 kJ/kg	1285:1320	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	2	25	theme	polyethylene	363:374	arg1	glycol					376:381	polyethylene glycol	363:381	polyethylene glycol (PEG)	363:387	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	25	theme	polyethylene	363:374	arg1	PEG					384:386	PEG	384:386	PEG	384:386	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	8	26	theme	promising	1480:1488	arg1	potential					1490:1498	promising potential	1480:1498	promising potential for solar energy harvesting and utilization	1480:1542	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	4	27	theme	nanocellulose	651:663	arg1	foams					665:669	nanocellulose foams	651:669	nanocellulose foams	651:669	Selective chemical modifications of nanocellulose foams enhanced their shape-stability and compatibility with PCMs.					
36244531	5	28	theme	loading	813:819	arg1	levels					821:826	high PCM loading levels	804:826	high PCM loading levels (93.63 % for PEG and 91.77 % for Pw)	804:863	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	8	29	theme	phase	1178:1182	arg1	enthalpy					1191:1198	a phase change enthalpy	1176:1198	a phase change enthalpy of 143 kJ/kg	1176:1211	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	1	30	theme	phase	197:201	arg1	materials					210:218	organic phase change materials	189:218	organic phase change materials	189:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	5	31	theme	favorable	768:776	arg1	compatibility					778:790	favorable compatibility	768:790	favorable compatibility	768:790	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	8	32	theme	melting	1220:1226	arg1	temperature					1228:1238	a melting temperature	1218:1238	a melting temperature of 25.2 °C	1218:1249	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	5	33	theme	negligible	869:878	arg1	leakage					884:890	negligible PCM leakage	869:890	negligible PCM leakage (<2 %)	869:897	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	5	33	theme	negligible	869:878	arg1	%					896:896	<2 %	893:896	<2 %	893:896	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	8	34	theme	184 kJ/kg	1312:1320	arg1	enthalpy					1300:1307	a phase change enthalpy	1285:1307	a phase change enthalpy of 184 kJ/kg	1285:1320	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	1	35	theme	change	203:208	arg1	materials					210:218	organic phase change materials	189:218	organic phase change materials	189:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	6	36	theme	PCMs	947:950	arg1	performance					932:942	the heat transfer performance	914:942	the heat transfer performance of PCMs	914:950	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	8	37	theme	PCM	1367:1369	arg1	structures					1380:1389	53.4 °C. Novel PCM sandwich structures	1352:1389	53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1352:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	4	38	theme	Selective	615:623	arg1	modifications					634:646	Selective chemical modifications	615:646	Selective chemical modifications of nanocellulose foams	615:669	Selective chemical modifications of nanocellulose foams enhanced their shape-stability and compatibility with PCMs.					
36244531	1	39	theme	materials	210:218	arg1	conduction					175:184	inferior heat conduction	161:184	inferior heat conduction of organic phase change materials	161:218	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	1	39	theme	materials	210:218	arg1	issue					151:155	leakage issue	143:155	leakage issue	143:155	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	0	40	theme	phase	41:45	arg1	materials					54:62	composite phase change materials	31:62	composite phase change materials	31:62	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	8	41	theme	25.2 °C	1243:1249	arg1	temperature					1228:1238	a melting temperature	1218:1238	a melting temperature of 25.2 °C	1218:1249	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	3	42	theme	high	590:593	arg1	porosity					595:602	high porosity	590:602	high porosity (>94.5 %)	590:612	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	42	theme	high	590:593	arg1	%					611:611	>94.5 %	605:611	>94.5 %	605:611	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	43	theme	prepared	541:548	arg1	foams					550:554	The prepared foams	537:554	The prepared foams	537:554	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	5	44	theme	high	804:807	arg1	levels					821:826	high PCM loading levels	804:826	high PCM loading levels (93.63 % for PEG and 91.77 % for Pw)	804:863	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	0	45	theme	composite	31:39	arg1	materials					54:62	composite phase change materials	31:62	composite phase change materials	31:62	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	8	46	theme	energy	1510:1515	arg1	harvesting					1517:1526	solar energy harvesting	1504:1526	solar energy harvesting	1504:1526	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	8	47	theme	structures	1380:1389	arg1	temperature					1337:1347	a melting temperature	1327:1347	a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1327:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	5	48	theme	PCM	809:811	arg1	levels					821:826	high PCM loading levels	804:826	high PCM loading levels (93.63 % for PEG and 91.77 % for Pw)	804:863	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	0	49	theme	materials	54:62	arg1	application					16:26	application	16:26	application	16:26	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	0	49	theme	materials	54:62	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	8	50	theme	solar	1504:1508	arg1	harvesting					1517:1526	solar energy harvesting	1504:1526	solar energy harvesting	1504:1526	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	5	51	theme	foam	749:752	arg1	structure					754:762	The highly porous foam structure	731:762	The highly porous foam structure	731:762	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	8	52	theme	sandwich	1371:1378	arg1	structures					1380:1389	53.4 °C. Novel PCM sandwich structures	1352:1389	53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1352:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	6	53	theme	solar	1042:1046	arg1	heating					1048:1054	solar heating	1042:1054	solar heating	1042:1054	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	0	54	theme	change	47:52	arg1	materials					54:62	composite phase change materials	31:62	composite phase change materials	31:62	Preparation and application of composite phase change materials stabilized by cellulose nanofibril-based foams for thermal energy storage.					
36244531	2	55	theme	transfer	515:522	arg1	performance					524:534	the heat transfer performance	506:534	the heat transfer performance	506:534	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	5	56	dep	levels	821:826	arg1	%					855:855	91.77 %	849:855	91.77 % for Pw	849:862	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	5	56	dep	levels	821:826	arg1	%					835:835	93.63 %	829:835	93.63 % for PEG	829:843	The highly porous foam structure and favorable compatibility resulted in high PCM loading levels (93.63 % for PEG and 91.77 % for Pw) and negligible PCM leakage (<2 %).					
36244531	8	57	theme	143 kJ/kg	1203:1211	arg1	enthalpy					1191:1198	a phase change enthalpy	1176:1198	a phase change enthalpy of 143 kJ/kg	1176:1211	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	2	58	theme	heat	510:513	arg1	performance					524:534	the heat transfer performance	506:534	the heat transfer performance	506:534	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	6	59	theme	transfer	923:930	arg1	performance					932:942	the heat transfer performance	914:942	the heat transfer performance of PCMs	914:950	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	4	60	theme	foams	665:669	arg1	modifications					634:646	Selective chemical modifications	615:646	Selective chemical modifications of nanocellulose foams	615:669	Selective chemical modifications of nanocellulose foams enhanced their shape-stability and compatibility with PCMs.					
36244531	8	61	theme	composite	1406:1414	arg1	PCMs					1416:1419	these composite PCMs	1400:1419	these composite PCMs	1400:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	8	62	theme	composite	1261:1269	arg1	PCM					1271:1273	Pw-based composite PCM	1252:1273	Pw-based composite PCM	1252:1273	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	1	63	theme	leakage	143:149	arg1	issue					151:155	leakage issue	143:155	leakage issue	143:155	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	8	64	theme	PEG-based	1142:1150	arg1	PCM					1162:1164	PEG-based composite PCM	1142:1164	PEG-based composite PCM	1142:1164	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	3	65	contain	had	556:558	arg2	%					611:611	>94.5 %	605:611	>94.5 %	605:611	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	65	contain	had	556:558	arg2	<67.3 kg/m3					573:583	<67.3 kg/m3	573:583	<67.3 kg/m3	573:583	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	65	contain	had	556:558	arg1	foams					550:554	The prepared foams	537:554	The prepared foams	537:554	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	65	contain	had	556:558	arg2	porosity					595:602	high porosity	590:602	high porosity (>94.5 %)	590:612	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	65	contain	had	556:558	arg2	density					564:570	low density	560:570	low density (<67.3 kg/m3)	560:584	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	2	66	theme	carbon	453:458	arg1	CNTs					471:474	CNTs	471:474	CNTs	471:474	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	66	theme	carbon	453:458	arg1	nanotubes					460:468	multiwalled carbon nanotubes	441:468	multiwalled carbon nanotubes (CNTs)	441:475	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	8	67	theme	53.4 °C.	1352:1359	arg1	structures					1380:1389	53.4 °C. Novel PCM sandwich structures	1352:1389	53.4 °C. Novel PCM sandwich structures based on these composite PCMs	1352:1419	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	2	68	theme	paraffin	393:400	arg1	Pw					407:408	Pw	407:408	Pw	407:408	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	68	theme	paraffin	393:400	arg1	wax					402:404	paraffin wax	393:404	paraffin wax (Pw)	393:409	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	1	69	theme	issue	151:155	arg1	PCMs					221:224	The leakage issue and inferior heat conduction of organic phase change materials (PCMs)	139:225	The leakage issue and inferior heat conduction of organic phase change materials (PCMs)	139:225	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36244531	8	70	theme	composite	1152:1160	arg1	PCM					1162:1164	PEG-based composite PCM	1142:1164	PEG-based composite PCM	1142:1164	PEG-based composite PCM exhibited a phase change enthalpy of 143 kJ/kg with a melting temperature of 25.2 °C; Pw-based composite PCM exhibited a phase change enthalpy of 184 kJ/kg with a melting temperature of 53.4 °C. Novel PCM sandwich structures based on these composite PCMs and a thermoelectric generator were designed and displayed promising potential for solar energy harvesting and utilization.					
36244531	6	71	theme	heat	918:921	arg1	performance					932:942	the heat transfer performance	914:942	the heat transfer performance of PCMs	914:950	CNTs improved the heat transfer performance of PCMs, as evidenced by the improved thermal conductivities and boosted temperature rises during solar heating.					
36244531	2	72	theme	multiwalled	441:451	arg1	CNTs					471:474	CNTs	471:474	CNTs	471:474	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	72	theme	multiwalled	441:451	arg1	nanotubes					460:468	multiwalled carbon nanotubes	441:468	multiwalled carbon nanotubes (CNTs)	441:475	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	3	73	theme	low	560:562	arg1	<67.3 kg/m3					573:583	<67.3 kg/m3	573:583	<67.3 kg/m3	573:583	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	3	73	theme	low	560:562	arg1	density					564:570	low density	560:570	low density (<67.3 kg/m3)	560:584	The prepared foams had low density (<67.3 kg/m3) and high porosity (>94.5 %).					
36244531	2	74	theme	porous	342:347	arg1	foams					315:319	cellulose nanofibril (CNF)-based foams	282:319	cellulose nanofibril (CNF)-based foams	282:319	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	2	74	theme	porous	342:347	arg1	scaffolds					349:357	the porous scaffolds	338:357	the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage	338:434	In the present study, cellulose nanofibril (CNF)-based foams were prepared as the porous scaffolds for polyethylene glycol (PEG) and paraffin wax (Pw) to prevent their leakage, and multiwalled carbon nanotubes (CNTs) were incorporated to improve the heat transfer performance.					
36244531	1	75	theme	actual	239:244	arg1	applications					246:257	their actual applications	233:257	their actual applications	233:257	The leakage issue and inferior heat conduction of organic phase change materials (PCMs) limit their actual applications.					
36098188	8	0	theme	CNCs-ZnO-Ag	1696:1706	arg1	composite					1708:1716	The CNCs-ZnO-Ag composite	1692:1716	The CNCs-ZnO-Ag composite	1692:1716	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	8	0	theme	CNCs-ZnO-Ag	1696:1706	arg1	ready					1721:1725	ready	1721:1725	ready	1721:1725	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	1	1	theme	Bacterial	142:150	arg1	BC					163:164	BC	163:164	BC	163:164	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	1	theme	Bacterial	142:150	arg1	cellulose					152:160	Bacterial cellulose	142:160	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	sup&gt					1324:1329	sup&gt	1324:1329	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	1&lt					1331:1334	1&lt	1331:1334	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	/sup&gt					1312:1318	/sup&gt	1312:1318	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	&lt					1320:1322	&lt	1320:1322	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	/sup&gt					1336:1342	/sup&gt	1336:1342	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	sup&gt					1301:1306	sup&gt	1301:1306	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	2	dep	mL&lt	1295:1299	arg1	&lt					1308:1310	&lt	1308:1310	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	4	3	theme	different	697:705	arg1	samples					717:723	four different composite samples	692:723	four different composite samples	692:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	4	4	theme	behaviour	679:687	arg1	scavenging					652:661	the scavenging	648:661	the scavenging of free radical behaviour of four different composite samples	648:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	8	5	dep	&lt	1800:1802	arg1	study					1827:1831	study	1827:1831	&lt;i&gt;in vivo&lt;/i&gt; study	1800:1831	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	8	5	dep	&lt	1800:1802	arg1	/i&gt					1820:1824	/i&gt	1820:1824	&lt;i&gt;in vivo&lt;/i&gt; study	1800:1831	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	8	5	dep	&lt	1800:1802	arg1	i&gt					1804:1807	i&gt;	1804:1808	&lt;i&gt;in vivo&lt;/i&gt; study	1800:1831	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	6	6	theme	related	1520:1526	arg1	composite					1510:1518	CNCs-ZnO-Ag composite	1498:1518	CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1498:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	7	7	from	activity	1625:1632	arg1	form					1642:1645	nano form	1637:1645	nano form	1637:1645	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	3	8	dep	&lt	450:452	arg1	&lt					481:483	&lt	481:483	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.	450:608	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	3	8	dep	&lt	450:452	arg1	Methods					473:479	Methods	473:479	Methods	473:479	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	3	8	dep	&lt	450:452	arg1	Materials					459:467	Materials	459:467	Materials	459:467	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	3	8	dep	&lt	450:452	arg1	/b&gt					485:489	/b&gt	485:489	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.	450:608	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	3	8	dep	&lt	450:452	arg1	b&gt					454:457	b&gt	454:457	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.	450:608	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	7	9	theme	Bacterial	1592:1600	arg1	cellulose					1602:1610	Bacterial cellulose	1592:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	0	10	theme	Nano	52:55	arg1	Components					84:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	0	11	theme	Microbial	42:50	arg1	Components					84:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	4	12	used	used	630:633	arg2	method					619:624	The DPPH method	610:624	The DPPH method	610:624	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	4	13	theme	composite	707:715	arg1	samples					717:723	four different composite samples	692:723	four different composite samples	692:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	6	14	theme	μg	1442:1443	arg1	mL&lt					1445:1449	75 μg mL&lt	1439:1449	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	8	15	from	i&gt	1804:1807	arg1	vivo&lt					1812:1818	vivo&lt	1812:1818	vivo&lt	1812:1818	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	7	16	dep	&lt	1561:1563	arg1	/b&gt					1585:1589	/b&gt	1585:1589	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	7	16	dep	&lt	1561:1563	arg1	cellulose					1602:1610	Bacterial cellulose	1592:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	7	16	dep	&lt	1561:1563	arg1	&lt					1581:1583	&lt	1581:1583	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	7	16	dep	&lt	1561:1563	arg1	Conclusion					1570:1579	Conclusion	1570:1579	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	7	16	dep	&lt	1561:1563	arg1	b&gt					1565:1568	b&gt	1565:1568	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose	1561:1610	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	4	17	theme	radical	671:677	arg1	behaviour					679:687	free radical behaviour	666:687	free radical behaviour of four different composite samples	666:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	4	18	theme	DPPH	614:617	arg1	method					619:624	The DPPH method	610:624	The DPPH method	610:624	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	4	19	theme	free	666:669	arg1	behaviour					679:687	free radical behaviour	666:687	free radical behaviour of four different composite samples	666:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	5	20	contain	had	1345:1347	arg1	BC					1273:1274	BC	1273:1274	BC	1273:1274	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	20	contain	had	1345:1347	arg2	times					1358:1362	clotting times	1349:1362	clotting times that were nearly identical to the control	1349:1404	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	20	contain	had	1345:1347	arg1	composite					1262:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	20	contain	had	1345:1347	arg1	AgNPs					1280:1284	AgNPs	1280:1284	AgNPs	1280:1284	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	6	21	theme	composite	1510:1518	arg1	/sup&gt					1486:1492	/sup&gt;	1486:1493	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	5	22	theme	CNCs-ZnO-Ag	1250:1260	arg1	BC					1273:1274	BC	1273:1274	BC	1273:1274	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	22	theme	CNCs-ZnO-Ag	1250:1260	arg1	composite					1262:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	22	theme	CNCs-ZnO-Ag	1250:1260	arg1	AgNPs					1280:1284	AgNPs	1280:1284	AgNPs	1280:1284	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	2	23	theme	nano	380:383	arg1	CNCs					403:406	CNCs	403:406	CNCs	403:406	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	23	theme	nano	380:383	arg1	composite					409:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	24	theme	cellulose-ZnO-Ag	385:400	arg1	CNCs					403:406	CNCs	403:406	CNCs	403:406	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	24	theme	cellulose-ZnO-Ag	385:400	arg1	composite					409:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	1	25	theme	Gluconacetobacter	249:265	arg1	xylinus&lt					267:276	Gluconacetobacter xylinus&lt	249:276	&lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	240:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	4	26	theme	samples	717:723	arg1	behaviour					679:687	free radical behaviour	666:687	free radical behaviour of four different composite samples	666:723	The DPPH method was used to calculate the scavenging of free radical behaviour of four different composite samples.					
36098188	8	27	theme	pharmaceutical	1731:1744	arg1	application					1746:1756	pharmaceutical application	1731:1756	pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study	1731:1831	The CNCs-ZnO-Ag composite is ready for pharmaceutical application as an antioxidant and anticoagulant after &lt;i&gt;in vivo&lt;/i&gt; study.					
36098188	2	28	theme	study	308:312	arg1	objective					290:298	The objective	286:298	The objective of this study	286:312	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	29	theme	microbial	370:378	arg1	CNCs					403:406	CNCs	403:406	CNCs	403:406	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	29	theme	microbial	370:378	arg1	composite					409:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	a microbial nano cellulose-ZnO-Ag (CNCs) composite	368:417	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	30	theme	components	427:436	arg1	anticoagulant					351:363	anticoagulant	351:363	anticoagulant	351:363	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	30	theme	components	427:436	arg1	antioxidant					335:345	antioxidant	335:345	antioxidant	335:345	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	5	31	theme	μg	1292:1293	arg1	mL&lt					1295:1299	25 μg mL&lt	1289:1299	25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt;	1289:1343	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	6	32	theme	CNCs-ZnO-Ag	1498:1508	arg1	composite					1510:1518	CNCs-ZnO-Ag composite	1498:1518	CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1498:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	1	33	theme	microbial	172:180	arg1	biopolymer					196:205	a microbial extracellular biopolymer	170:205	a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	170:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	33	theme	microbial	172:180	arg1	&lt					96:98	&lt	96:98	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	3	34	theme	nano	523:526	arg1	synthesis					555:563	nano cellulose-ZnO-Ag composite synthesis	523:563	nano cellulose-ZnO-Ag composite synthesis	523:563	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	1	35	theme	extracellular	182:194	arg1	biopolymer					196:205	a microbial extracellular biopolymer	170:205	a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	170:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	35	theme	extracellular	182:194	arg1	&lt					96:98	&lt	96:98	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	0	36	theme	Cellulose-ZnO-Ag	57:72	arg1	Components					84:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	5	37	from	mL&lt	1295:1299	arg1	BC					1273:1274	BC	1273:1274	BC	1273:1274	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	37	from	mL&lt	1295:1299	arg1	composite					1262:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite	1246:1270	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	5	37	from	mL&lt	1295:1299	arg1	AgNPs					1280:1284	AgNPs	1280:1284	AgNPs	1280:1284	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	3	38	used	used	514:517	arg2	components					498:507	Three components	492:507	Three components	492:507	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	2	39	theme	composite	409:417	arg1	anticoagulant					351:363	anticoagulant	351:363	anticoagulant	351:363	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	2	39	theme	composite	409:417	arg1	antioxidant					335:345	antioxidant	335:345	antioxidant	335:345	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	1	40	dep	&lt	240:242	arg1	/i&gt					278:282	/i&gt	278:282	&lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	240:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	40	dep	&lt	240:242	arg1	i&gt					244:247	i&gt	244:247	&lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	240:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	40	dep	&lt	240:242	arg1	xylinus&lt					267:276	Gluconacetobacter xylinus&lt	249:276	&lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	240:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	BC					163:164	BC	163:164	BC	163:164	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	b&gt					100:103	b&gt	100:103	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	Background					105:114	Background	105:114	Background	105:114	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	/b&gt					135:139	/b&gt	135:139	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	Objectives					120:129	Objectives	120:129	Objectives	120:129	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	cellulose					152:160	Bacterial cellulose	142:160	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	1	41	dep	&lt	96:98	arg1	&lt					131:133	&lt	131:133	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC)	96:165	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36098188	3	42	theme	composite	545:553	arg1	synthesis					555:563	nano cellulose-ZnO-Ag composite synthesis	523:563	nano cellulose-ZnO-Ag composite synthesis	523:563	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	7	43	theme	nano	1637:1640	arg1	form					1642:1645	nano form	1637:1645	nano form	1637:1645	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	2	44	dep	antioxidant	335:345	arg1	the					331:333	the	331:333	the	331:333	The objective of this study was to determine the antioxidant and anticoagulant of a microbial nano cellulose-ZnO-Ag (CNCs) composite and its components separately.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	/sup&gt					1462:1468	/sup&gt	1462:1468	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	&lt					1470:1472	&lt	1470:1472	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	/sup&gt					1486:1492	/sup&gt;	1486:1493	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	sup&gt					1451:1456	sup&gt	1451:1456	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	&lt					1458:1460	&lt	1458:1460	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	sup&gt					1474:1479	sup&gt	1474:1479	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	6	45	dep	mL&lt	1445:1449	arg1	1&lt					1481:1484	1&lt	1481:1484	75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec	1439:1558	The APTT increased to 56 Sec at 75 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; of CNCs-ZnO-Ag composite related to control that recorded 33 Sec.					
36098188	5	46	theme	clotting	1349:1356	arg1	times					1358:1362	clotting times	1349:1362	clotting times that were nearly identical to the control	1349:1404	The CNCs-ZnO-Ag composite, BC and AgNPs at 25 μg mL&lt;sup&gt;&lt;/sup&gt;&lt;sup&gt;1&lt;/sup&gt; had clotting times that were nearly identical to the control.					
36098188	0	47	theme	Components	84:93	arg1	Antioxidant					0:10	Antioxidant	0:10	Antioxidant	0:10	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	0	47	theme	Components	84:93	arg1	Activity					30:37	Anticoagulant Activity	16:37	Anticoagulant Activity	16:37	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	3	48	theme	cellulose-ZnO-Ag	528:543	arg1	synthesis					555:563	nano cellulose-ZnO-Ag composite synthesis	523:563	nano cellulose-ZnO-Ag composite synthesis	523:563	&lt;b&gt;Materials and Methods:&lt;/b&gt; Three components were used for nano cellulose-ZnO-Ag composite synthesis, Ag-nanoparticles, ZnO-nanoparticles and BC.					
36098188	7	49	theme	new	1621:1623	arg1	activity					1625:1632	new activity	1621:1632	new activity in nano form	1621:1645	&lt;b&gt;Conclusion:&lt;/b&gt; Bacterial cellulose acquired new activity in nano form and also when conjugated with nanoparticles.					
36098188	0	50	theme	Composite	74:82	arg1	Components					84:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Microbial Nano Cellulose-ZnO-Ag Composite Components	42:93	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	0	51	theme	Anticoagulant	16:28	arg1	Activity					30:37	Anticoagulant Activity	16:37	Anticoagulant Activity	16:37	Antioxidant and Anticoagulant Activity of Microbial Nano Cellulose-ZnO-Ag Composite Components.					
36098188	1	52	theme	microbial	217:225	arg1	strains					227:233	microbial strains	217:233	microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;	217:283	&lt;b&gt;Background and Objectives:&lt;/b&gt; Bacterial cellulose (BC) is a microbial extracellular biopolymer formed by microbial strains like &lt;i&gt;Gluconacetobacter xylinus&lt;/i&gt;.					
36699698	2	0	theme	ER-associated	588:600	arg1	ERAD					615:618	ERAD	615:618	ERAD	615:618	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	0	theme	ER-associated	588:600	arg1	degradation					602:612	ER-associated degradation	588:612	ER-associated degradation (ERAD)	588:619	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	8	1	theme	ESP	2191:2193	arg1	members					2206:2212	ESP transitory members	2191:2212	ESP transitory members	2191:2212	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	3	2	theme	cellular	672:679	arg1	homeostasis					681:691	cellular homeostasis	672:691	cellular homeostasis	672:691	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	8	3	theme	misfolded	1882:1890	arg1	degradation					1900:1910	misfolded protein degradation	1882:1910	misfolded protein degradation	1882:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	6	4	theme	extracellular	1443:1455	arg1	matrix					1457:1462	extracellular matrix	1443:1462	extracellular matrix	1443:1462	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	8	5	theme	members	2206:2212	arg1	characterization					2171:2186	characterization	2171:2186	characterization	2171:2186	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	8	5	theme	members	2206:2212	arg1	accumulation					2154:2165	accumulation	2154:2165	accumulation	2154:2165	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	9	6	theme	kifunensine	2441:2451	arg1	treatment					2453:2461	kifunensine treatment	2441:2461	kifunensine treatment	2441:2461	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	1	7	theme	cell-cell	279:287	arg1	communication					289:301	cell-cell communication	279:301	cell-cell communication	279:301	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	8	8	theme	mannosidase	2224:2234	arg1	I					2242:2242	mannosidase class I	2224:2242	mannosidase class I inhibition	2224:2253	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	3	9	theme	analysis	706:713	arg1	studies					715:721	large-scale analysis studies	694:721	large-scale analysis studies	694:721	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	8	10	theme	integrin	2034:2041	arg1	family					2043:2048	the integrin family	2030:2048	the integrin family of proteins such as ITGA1 and ITGA4	2030:2084	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	8	11	theme	I	2242:2242	arg1	inhibition					2244:2253	mannosidase class I inhibition	2224:2253	mannosidase class I inhibition	2224:2253	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	3	12	theme	molecules	740:748	arg1	pool					732:735	this pool	727:735	this pool of molecules	727:748	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	1	13	theme	protein	195:201	arg1	folding					203:209	protein folding	195:209	protein folding	195:209	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	2	14	theme	N-glycan	542:549	arg1	ERQC					578:581	ERQC	578:581	ERQC	578:581	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	14	theme	N-glycan	542:549	arg1	control					569:575	the N-glycan dependent quality control	538:575	the N-glycan dependent quality control (ERQC)	538:582	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	5	15	dep	chain	1237:1241	arg1	the					1225:1227	the	1225:1227	the	1225:1227	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	9	16	theme	associated	2489:2498	arg1	responses					2509:2517	the potential associated cellular responses	2475:2517	the potential associated cellular responses	2475:2517	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	6	17	theme	Man9	1522:1525	arg1	N-glycans					1527:1535	Man9 N-glycans	1522:1535	Man9 N-glycans	1522:1535	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	7	18	theme	mannosidases	1665:1676	arg1	inhibition					1643:1652	decreased subsequent inhibition	1622:1652	decreased subsequent inhibition of class I mannosidases	1622:1676	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	4	19	theme	glycomics	900:908	arg1	analyses					932:939	deglycoproteomics analyses	914:939	deglycoproteomics analyses	914:939	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	4	19	theme	glycomics	900:908	arg1	combination					885:895	a combination	883:895	a combination of glycomics	883:908	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	4	20	theme	ESP	1095:1097	arg1	fraction					1099:1106	ESP fraction	1095:1106	ESP fraction in melanoma cells	1095:1124	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	8	21	theme	suggested	1949:1957	arg1	candidates					1980:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	4	22	gly	glycoprotein	1063:1074	arg1	glycoprotein					1063:1074	the steady-state oligomannosidic glycoprotein load	1030:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	8	23	theme	proteins	2053:2060	arg1	family					2043:2048	the integrin family	2030:2048	the integrin family of proteins such as ITGA1 and ITGA4	2030:2084	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	7	24	theme	class	1657:1661	arg1	mannosidases					1665:1676	class I mannosidases	1657:1676	class I mannosidases	1657:1676	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	4	25	theme	custom	857:862	arg1	workflow					864:871	a custom workflow	855:871	a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion	855:1013	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	8	26	theme	substrate	1970:1978	arg1	candidates					1980:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	7	27	theme	responsible	1759:1769	arg1	FUT8					1742:1745	FUT8	1742:1745	FUT8	1742:1745	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	7	27	theme	responsible	1759:1769	arg1	enzyme					1752:1757	the enzyme	1748:1757	the enzyme responsible for fucosylation	1748:1786	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	2	28	theme	quality	561:567	arg1	ERQC					578:581	ERQC	578:581	ERQC	578:581	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	28	theme	quality	561:567	arg1	control					569:575	the N-glycan dependent quality control	538:575	the N-glycan dependent quality control (ERQC)	538:582	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	3	29	theme	early	788:792	arg1	ESP					813:815	ESP	813:815	ESP	813:815	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	3	29	theme	early	788:792	arg1	pathway					804:810	the early secretory pathway	784:810	the early secretory pathway (ESP)	784:816	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	7	30	theme	decreased	1622:1630	arg1	inhibition					1643:1652	decreased subsequent inhibition	1622:1652	decreased subsequent inhibition of class I mannosidases	1622:1676	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	4	31	theme	lectin	948:953	arg1	affinity					955:962	lectin affinity	948:962	lectin affinity	948:962	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	0	32	theme	secretory	55:63	arg1	pathway					65:71	the early secretory pathway	45:71	the early secretory pathway	45:71	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	7	33	theme	FUT8	1742:1745	arg1	level					1733:1737	a general lower protein level	1709:1737	a general lower protein level of FUT8, the enzyme responsible for fucosylation	1709:1786	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	5	34	theme	chain	1237:1241	arg1	quantification					1202:1215	glycosite relative quantification	1183:1215	glycosite relative quantification of both the peptide chain and carbohydrate structure	1183:1268	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	9	35	theme	associated	2278:2287	arg1	dataset					2289:2295	the associated dataset	2274:2295	the associated dataset	2274:2295	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	1	36	theme	various	161:167	arg1	functions					180:188	various biological functions	161:188	various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response	161:321	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	4	37	theme	deglycoproteomics	914:930	arg1	analyses					932:939	deglycoproteomics analyses	914:939	deglycoproteomics analyses	914:939	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	5	38	theme	carbohydrate	1247:1258	arg1	structure					1260:1268	carbohydrate structure	1247:1268	carbohydrate structure	1247:1268	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	0	39	theme	I	82:82	arg1	inhibition					112:121	class I mannosidase pharmacological inhibition	76:121	class I mannosidase pharmacological inhibition	76:121	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	5	40	with	cells	1273:1277	arg1	activity					1294:1301	inhibited activity	1284:1301	inhibited activity of class I mannosidases after kifunensine treatment	1284:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	3	41	dep	limited	824:830	arg1	addressed					832:840	addressed	832:840	were limited addressed	819:840	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	7	42	theme	lower	1719:1723	arg1	level					1733:1737	a general lower protein level	1709:1737	a general lower protein level of FUT8, the enzyme responsible for fucosylation	1709:1786	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	5	43	theme	mannosidases	1314:1325	arg1	activity					1294:1301	inhibited activity	1284:1301	inhibited activity of class I mannosidases after kifunensine treatment	1284:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	5	44	theme	relative	1193:1200	arg1	quantification					1202:1215	glycosite relative quantification	1183:1215	glycosite relative quantification of both the peptide chain and carbohydrate structure	1183:1268	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	2	45	theme	protein	474:480	arg1	sorting					482:488	the early protein sorting	464:488	the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD)	464:619	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	8	46	theme	key	1863:1865	arg1	mannosidase					1867:1877	a key mannosidase	1861:1877	a key mannosidase in misfolded protein degradation	1861:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	5	47	theme	kifunensine	1333:1343	arg1	treatment					1345:1353	kifunensine treatment	1333:1353	kifunensine treatment	1333:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	6	48	theme	cell	1420:1423	arg1	communication					1425:1437	cell communication	1420:1437	cell communication via extracellular matrix	1420:1462	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	8	49	from	degradation	1900:1910	arg1	downregulation					1843:1856	downregulation	1843:1856	downregulation of a key mannosidase in misfolded protein degradation	1843:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	3	50	from	pathway	804:810	arg1	proteins					770:777	proteins	770:777	proteins from the early secretory pathway (ESP)	770:816	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	5	51	gly	glycosite	1183:1191	arg2	glycosite					1183:1191	glycosite	1183:1191	glycosite	1183:1191	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	2	52	theme	outstanding	425:435	arg1	role					437:440	an outstanding role	422:440	an outstanding role	422:440	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	0	53	theme	altered	13:19	arg1	space					36:40	the altered glycoproteomic space	9:40	the altered glycoproteomic space of the early secretory pathway	9:71	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	1	54	theme	immune	307:312	arg1	response					314:321	immune response	307:321	immune response	307:321	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	4	55	theme	Endoglycosidase	978:992	arg1	H					994:994	Endoglycosidase H	978:994	selective Endoglycosidase H (Endo H) digestion	968:1013	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	4	55	theme	Endoglycosidase	978:992	arg1	H					1002:1002	Endo H	997:1002	Endo H	997:1002	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	5	56	theme	class	1306:1310	arg1	mannosidases					1314:1325	class I mannosidases	1306:1325	class I mannosidases after kifunensine treatment	1306:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	9	57	theme	glycoprotein	2352:2363	arg1	fraction					2365:2372	the oligomannosidic glycoprotein fraction	2332:2372	the oligomannosidic glycoprotein fraction	2332:2372	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	6	58	theme	transient	1390:1398	arg1	most					1370:1373	most	1370:1373	most	1370:1373	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	6	58	theme	transient	1390:1398	arg1	ESP					1382:1384	the ESP	1378:1384	the ESP	1378:1384	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	6	58	theme	transient	1390:1398	arg1	clients					1400:1406	transient clients	1390:1406	transient clients involved in cell communication via extracellular matrix	1390:1462	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	6	58	theme	transient	1390:1398	arg1	communication					1496:1508	integrin-mediated communication	1478:1508	integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells	1478:1564	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	4	59	theme	selective	968:976	arg1	digestion					1005:1013	selective Endoglycosidase H (Endo H) digestion	968:1013	selective Endoglycosidase H (Endo H) digestion	968:1013	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	2	60	theme	complex	358:364	arg1	system					366:371	a complex system	356:371	a complex system	356:371	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	4	61	theme	oligomannosidic	1047:1061	arg1	load					1076:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	8	62	theme	endogenous	1959:1968	arg1	candidates					1980:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	3	63	theme	large-scale	694:704	arg1	studies					715:721	large-scale analysis studies	694:721	large-scale analysis studies	694:721	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	8	64	theme	protein	1892:1898	arg1	degradation					1900:1910	misfolded protein degradation	1882:1910	misfolded protein degradation	1882:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	1	65	theme	secretory	256:264	arg1	compartment					266:276	the conventional secretory compartment	239:276	the conventional secretory compartment	239:276	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	5	66	theme	glycosite	1183:1191	arg1	quantification					1202:1215	glycosite relative quantification	1183:1215	glycosite relative quantification of both the peptide chain and carbohydrate structure	1183:1268	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	8	67	theme	transitory	2195:2204	arg1	members					2206:2212	ESP transitory members	2191:2212	ESP transitory members	2191:2212	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	4	68	theme	melanoma	1111:1118	arg1	cells					1120:1124	melanoma cells	1111:1124	melanoma cells	1111:1124	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	1	69	theme	biological	169:178	arg1	functions					180:188	various biological functions	161:188	various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response	161:321	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	8	70	theme	novel	1928:1932	arg1	candidates					1980:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	both novel and previously suggested endogenous substrate candidates	1923:1989	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	6	71	theme	kifunensine-treated	1540:1558	arg1	cells					1560:1564	kifunensine-treated cells	1540:1564	kifunensine-treated cells	1540:1564	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	8	72	theme	class	2236:2240	arg1	I					2242:2242	mannosidase class I	2224:2242	mannosidase class I inhibition	2224:2253	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	9	73	theme	potential	2479:2487	arg1	responses					2509:2517	the potential associated cellular responses	2475:2517	the potential associated cellular responses	2475:2517	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	4	74	from	fraction	1099:1106	arg1	cells					1120:1124	melanoma cells	1111:1124	melanoma cells	1111:1124	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	7	75	theme	I	1663:1663	arg1	mannosidases					1665:1676	class I mannosidases	1657:1676	class I mannosidases	1657:1676	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	5	76	from	workflow	1170:1177	arg1	cells					1273:1277	cells	1273:1277	cells with inhibited activity of class I mannosidases after kifunensine treatment	1273:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	9	77	theme	cellular	2500:2507	arg1	responses					2509:2517	the potential associated cellular responses	2475:2517	the potential associated cellular responses	2475:2517	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	7	78	theme	subsequent	1632:1641	arg1	inhibition					1643:1652	decreased subsequent inhibition	1622:1652	decreased subsequent inhibition of class I mannosidases	1622:1676	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	2	79	from	Reticulum	520:528	arg1	ERAD					615:618	ERAD	615:618	ERAD	615:618	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	79	from	Reticulum	520:528	arg1	ERQC					578:581	ERQC	578:581	ERQC	578:581	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	79	from	Reticulum	520:528	arg1	control					569:575	the N-glycan dependent quality control	538:575	the N-glycan dependent quality control (ERQC)	538:582	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	79	from	Reticulum	520:528	arg1	degradation					602:612	ER-associated degradation	588:612	ER-associated degradation (ERAD)	588:619	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	8	80	from	downregulation	1843:1856	arg1	degradation					1900:1910	misfolded protein degradation	1882:1910	misfolded protein degradation	1882:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	5	81	theme	structure	1260:1268	arg1	quantification					1202:1215	glycosite relative quantification	1183:1215	glycosite relative quantification of both the peptide chain and carbohydrate structure	1183:1268	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	2	82	contain	have	417:420	arg2	role					437:440	an outstanding role	422:440	an outstanding role	422:440	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	82	contain	have	417:420	arg1	those					398:402	those	398:402	those	398:402	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	83	theme	dependent	551:559	arg1	ERQC					578:581	ERQC	578:581	ERQC	578:581	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	83	theme	dependent	551:559	arg1	control					569:575	the N-glycan dependent quality control	538:575	the N-glycan dependent quality control (ERQC)	538:582	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	3	84	theme	secretory	794:802	arg1	ESP					813:815	ESP	813:815	ESP	813:815	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	3	84	theme	secretory	794:802	arg1	pathway					804:810	the early secretory pathway	784:810	the early secretory pathway (ESP)	784:816	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	0	85	theme	pathway	65:71	arg1	space					36:40	the altered glycoproteomic space	9:40	the altered glycoproteomic space of the early secretory pathway	9:71	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	1	86	theme	key	145:147	arg1	process					149:155	a key process	143:155	a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response	143:321	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	1	86	theme	key	145:147	arg1	N-glycosylation					124:138	N-glycosylation	124:138	N-glycosylation	124:138	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
36699698	8	87	from	mannosidase	1867:1877	arg1	degradation					1900:1910	misfolded protein degradation	1882:1910	misfolded protein degradation	1882:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	5	88	theme	peptide	1229:1235	arg1	chain					1237:1241	peptide chain	1229:1241	peptide chain	1229:1241	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	0	89	theme	class	76:80	arg1	inhibition					112:121	class I mannosidase pharmacological inhibition	76:121	class I mannosidase pharmacological inhibition	76:121	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	0	90	theme	mannosidase	84:94	arg1	inhibition					112:121	class I mannosidase pharmacological inhibition	76:121	class I mannosidase pharmacological inhibition	76:121	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	5	91	theme	I	1312:1312	arg1	mannosidases					1314:1325	class I mannosidases	1306:1325	class I mannosidases after kifunensine treatment	1306:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	7	92	theme	protein	1725:1731	arg1	level					1733:1737	a general lower protein level	1709:1737	a general lower protein level of FUT8, the enzyme responsible for fucosylation	1709:1786	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	2	93	theme	Endoplasmic	508:518	arg1	Reticulum					520:528	the Endoplasmic Reticulum	504:528	the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD)	504:619	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	2	93	theme	Endoplasmic	508:518	arg1	ER					531:532	ER	531:532	ER	531:532	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	8	94	theme	family	2043:2048	arg1	members					2019:2025	members	2019:2025	members of the integrin family of proteins such as ITGA1 and ITGA4	2019:2084	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	8	94	theme	family	2043:2048	arg1	LAMB2					2010:2014	LAMB2	2010:2014	LAMB2	2010:2014	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	8	94	theme	family	2043:2048	arg1	HLA-B					2003:2007	HLA-B	2003:2007	HLA-B	2003:2007	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	8	94	theme	family	2043:2048	arg1	PCDH2					1996:2000	PCDH2	1996:2000	PCDH2	1996:2000	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	7	95	theme	general	1711:1717	arg1	level					1733:1737	a general lower protein level	1709:1737	a general lower protein level of FUT8, the enzyme responsible for fucosylation	1709:1786	Moreover, our results reveal that core-fucosylation is decreased subsequent inhibition of class I mannosidases and this could be explained by a general lower protein level of FUT8, the enzyme responsible for fucosylation.					
36699698	4	96	theme	Endo	997:1000	arg1	H					994:994	Endoglycosidase H	978:994	selective Endoglycosidase H (Endo H) digestion	968:1013	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	4	96	theme	Endo	997:1000	arg1	H					1002:1002	Endo H	997:1002	Endo H	997:1002	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	5	97	theme	inhibited	1284:1292	arg1	activity					1294:1301	inhibited activity	1284:1301	inhibited activity of class I mannosidases after kifunensine treatment	1284:1353	All of these were assessed by applying our workflow for glycosite relative quantification of both the peptide chain and carbohydrate structure in cells with inhibited activity of class I mannosidases after kifunensine treatment.					
36699698	0	98	theme	glycoproteomic	21:34	arg1	space					36:40	the altered glycoproteomic space	9:40	the altered glycoproteomic space of the early secretory pathway	9:71	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	8	99	theme	mannosidase	1867:1877	arg1	downregulation					1843:1856	downregulation	1843:1856	downregulation of a key mannosidase in misfolded protein degradation	1843:1910	By comparing our data with results obtained following downregulation of a key mannosidase in misfolded protein degradation, we mapped both novel and previously suggested endogenous substrate candidates like PCDH2, HLA-B, LAMB2 or members of the integrin family of proteins such as ITGA1 and ITGA4, thus validating the findings obtained using our workflow regarding accumulation and characterization of ESP transitory members following mannosidase class I inhibition.					
36699698	9	100	theme	oligomannosidic	2336:2350	arg1	fraction					2365:2372	the oligomannosidic glycoprotein fraction	2332:2372	the oligomannosidic glycoprotein fraction	2332:2372	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	2	101	theme	early	468:472	arg1	sorting					482:488	the early protein sorting	464:488	the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD)	464:619	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	0	102	theme	pharmacological	96:110	arg1	inhibition					112:121	class I mannosidase pharmacological inhibition	76:121	class I mannosidase pharmacological inhibition	76:121	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	0	103	theme	early	49:53	arg1	pathway					65:71	the early secretory pathway	45:71	the early secretory pathway	45:71	Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition.					
36699698	4	104	theme	H	994:994	arg1	digestion					1005:1013	selective Endoglycosidase H (Endo H) digestion	968:1013	selective Endoglycosidase H (Endo H) digestion	968:1013	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	4	105	theme	steady-state	1034:1045	arg1	load					1076:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	3	106	theme	vital	641:645	arg1	these					631:635	these	631:635	these	631:635	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	3	106	theme	vital	641:645	arg1	processes					647:655	vital processes	641:655	vital processes	641:655	Although these are vital processes in maintaining cellular homeostasis, large-scale analysis studies for this pool of molecules, further denoted as proteins from the early secretory pathway (ESP), were limited addressed.					
36699698	6	107	theme	integrin-mediated	1478:1494	arg1	clients					1400:1406	transient clients	1390:1406	transient clients involved in cell communication via extracellular matrix	1390:1462	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	6	107	theme	integrin-mediated	1478:1494	arg1	communication					1496:1508	integrin-mediated communication	1478:1508	integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells	1478:1564	We found that most of the ESP are transient clients involved in cell communication via extracellular matrix, particularly integrin-mediated communication which adopt Man9 N-glycans in kifunensine-treated cells.					
36699698	9	108	gly	glycoprotein	2352:2363	arg1	glycoprotein					2352:2363	the oligomannosidic glycoprotein fraction	2332:2372	the oligomannosidic glycoprotein fraction	2332:2372	This workflow and the associated dataset not only allowed us to investigate the oligomannosidic glycoprotein fraction but also to delineate differences mediated at glycosite-level upon kifunensine treatment and outline the potential associated cellular responses.					
36699698	4	109	theme	glycoprotein	1063:1074	arg1	load					1076:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	the steady-state oligomannosidic glycoprotein load	1030:1079	Here, using a custom workflow employing a combination of glycomics and deglycoproteomics analyses, using lectin affinity and selective Endoglycosidase H (Endo H) digestion, we scrutinize the steady-state oligomannosidic glycoprotein load and delineate ESP fraction in melanoma cells.					
36699698	2	110	theme	mannosidases	376:387	arg1	system					366:371	a complex system	356:371	a complex system	356:371	This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early protein sorting associated to the Endoplasmic Reticulum (ER) in the N-glycan dependent quality control (ERQC) and ER-associated degradation (ERAD).					
36699698	1	111	theme	conventional	243:254	arg1	compartment					266:276	the conventional secretory compartment	239:276	the conventional secretory compartment	239:276	N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.					
35961171	6	0	theme	refined	984:990	arg1	basis					1017:1021	a reliable and refined theoretical and research basis	969:1021	a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp.	969:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	6	1	theme	nutritional	1041:1051	arg1	quality					1053:1059	the nutritional quality	1037:1059	the nutritional quality	1037:1059	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	6	2	theme	beneficial	1073:1082	arg1	ingredients					1084:1094	beneficial ingredients	1073:1094	beneficial ingredients	1073:1094	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	2	3	from	study	322:326	arg1	differences					347:357	the composition differences	331:357	the composition differences between males and females of three different Crassostrea sp	331:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	6	4	theme	data	1160:1163	arg1	support					1165:1171	data support	1160:1171	data support for the sex-regulated breeding of oysters	1160:1213	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	6	5	theme	functional	1112:1121	arg1	food					1123:1126	functional food	1112:1126	functional food of Crassostrea sp.	1112:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	5	6	theme	nutritional	906:916	arg1	higher					939:944	higher	939:944	higher	939:944	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	5	6	theme	nutritional	906:916	arg1	quality					918:924	the nutritional quality	902:924	the nutritional quality of males	902:933	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	3	7	theme	higher	528:533	arg1	protein					535:541	higher protein and taurine contents	528:562	protein	535:541	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	5	8	theme	omega-6	805:811	arg1	higher					857:862	higher	857:862	higher	857:862	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	5	8	theme	omega-6	805:811	arg1	ratio					824:828	The omega-3: omega-6 (n-3: n-6) ratio	792:828	The omega-3: omega-6 (n-3: n-6) ratio of males	792:837	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	6	9	theme	research	1008:1015	arg1	basis					1017:1021	a reliable and refined theoretical and research basis	969:1021	a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp.	969:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	2	10	theme	Crassostrea	404:414	arg1	sp					416:417	three different Crassostrea sp	388:417	three different Crassostrea sp	388:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	6	11	theme	oysters	1207:1213	arg1	breeding					1195:1202	the sex-regulated breeding	1177:1202	the sex-regulated breeding of oysters	1177:1213	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	2	12	theme	different	394:402	arg1	sp					416:417	three different Crassostrea sp	388:417	three different Crassostrea sp	388:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	3	13	theme	female	681:686	arg1	gametogenesis					688:700	female gametogenesis	681:700	female gametogenesis	681:700	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	14	theme	taurine	547:553	arg1	contents					555:562	higher protein and taurine contents	528:562	contents	555:562	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	1	15	theme	biochemical	190:200	arg1	composition					202:212	the biochemical composition	186:212	the biochemical composition of oysters	186:223	Gametogenesis can significantly affect the biochemical composition of oysters, but little research on the difference between sexes.					
35961171	2	16	theme	in-depth	313:320	arg1	study					322:326	the first in-depth study	303:326	the first in-depth study on the composition differences between males and females of three different Crassostrea sp	303:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	0	17	theme	composition	26:36	arg1	Comparison					0:9	Comparison	0:9	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.	0:145	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	0	18	theme	different	121:129	arg1	sp					143:144	three different Crassostrea sp	115:144	three different Crassostrea sp	115:144	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	2	19	theme	first	307:311	arg1	study					322:326	the first in-depth study	303:326	the first in-depth study on the composition differences between males and females of three different Crassostrea sp	303:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	6	20	theme	theoretical	992:1002	arg1	basis					1017:1021	a reliable and refined theoretical and research basis	969:1021	a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp.	969:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	0	21	theme	biochemical	14:24	arg1	composition					26:36	biochemical composition	14:36	biochemical composition	14:36	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	3	22	theme	special	616:622	arg1	pattern					632:638	special meiosis pattern	616:638	special meiosis pattern of eggs	616:646	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	1	23	theme	oysters	217:223	arg1	composition					202:212	the biochemical composition	186:212	the biochemical composition of oysters	186:223	Gametogenesis can significantly affect the biochemical composition of oysters, but little research on the difference between sexes.					
35961171	0	24	theme	nutritional	39:49	arg1	quality					51:57	nutritional quality	39:57	nutritional quality	39:57	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	3	25	theme	Zn	488:489	arg1	glycogen					464:471	glycogen	464:471	glycogen	464:471	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	25	theme	Zn	488:489	arg1	contents					491:498	Cu and Zn contents	481:498	Cu and Zn contents	481:498	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	0	26	theme	sp	143:144	arg1	females					104:110	females	104:110	females	104:110	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	0	26	theme	sp	143:144	arg1	males					94:98	males	94:98	males	94:98	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	3	27	theme	meiosis	624:630	arg1	pattern					632:638	special meiosis pattern	616:638	special meiosis pattern of eggs	616:646	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	6	28	theme	sex-regulated	1181:1193	arg1	breeding					1195:1202	the sex-regulated breeding	1177:1202	the sex-regulated breeding of oysters	1177:1213	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	3	29	from	maturity	580:587	arg1	females					569:575	females	569:575	females at maturity	569:587	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	0	30	theme	Crassostrea	131:141	arg1	sp					143:144	three different Crassostrea sp	115:144	three different Crassostrea sp	115:144	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	2	31	theme	sp	416:417	arg1	males					367:371	males	367:371	males	367:371	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	2	31	theme	sp	416:417	arg1	females					377:383	females	377:383	females	377:383	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	4	32	contain	had	739:741	arg1	females					731:737	females	731:737	females	731:737	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	4	32	contain	had	739:741	arg2	compositions					778:789	well-balanced essential amino acid compositions	743:789	well-balanced essential amino acid compositions	743:789	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	4	32	contain	had	739:741	arg1	males					721:725	males	721:725	males	721:725	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	5	33	theme	omega-3	796:802	arg1	higher					857:862	higher	857:862	higher	857:862	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	5	33	theme	omega-3	796:802	arg1	ratio					824:828	The omega-3: omega-6 (n-3: n-6) ratio	792:828	The omega-3: omega-6 (n-3: n-6) ratio of males	792:837	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	0	34	theme	quality	51:57	arg1	Comparison					0:9	Comparison	0:9	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.	0:145	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	6	35	theme	Crassostrea	1131:1141	arg1	food					1123:1126	functional food	1112:1126	functional food of Crassostrea sp.	1112:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	3	36	theme	eggs	643:646	arg1	pattern					632:638	special meiosis pattern	616:638	special meiosis pattern of eggs	616:646	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	5	37	dep	omega-6	805:811	arg1	n-6					819:821	n-6	819:821	n-6	819:821	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	2	38	theme	composition	335:345	arg1	differences					347:357	the composition differences	331:357	the composition differences between males and females of three different Crassostrea sp	331:417	Therefore, we conducted the first in-depth study on the composition differences between males and females of three different Crassostrea sp.					
35961171	3	39	contain	had	524:526	arg2	contents					555:562	higher protein and taurine contents	528:562	contents	555:562	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	39	contain	had	524:526	arg1	males					518:522	males	518:522	males	518:522	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	39	contain	had	524:526	arg2	protein					535:541	higher protein and taurine contents	528:562	protein	535:541	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	40	dep	higher	457:462	arg1	glycogen					464:471	glycogen	464:471	glycogen	464:471	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	40	dep	higher	457:462	arg1	contents					491:498	Cu and Zn contents	481:498	Cu and Zn contents	481:498	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	40	dep	higher	457:462	arg1	lipid					474:478	lipid	474:478	lipid	474:478	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	0	41	dep	composition	26:36	arg1	concentrations					71:84	concentrations	71:84	concentrations	71:84	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	3	42	dep	had	524:526	arg1	related					605:611	related	605:611	related	605:611	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	1	43	theme	little	230:235	arg1	research					237:244	little research	230:244	little research	230:244	Gametogenesis can significantly affect the biochemical composition of oysters, but little research on the difference between sexes.					
35961171	1	44	from	research	237:244	arg1	difference					253:262	the difference	249:262	the difference between sexes	249:276	Gametogenesis can significantly affect the biochemical composition of oysters, but little research on the difference between sexes.					
35961171	4	45	theme	well-balanced	743:755	arg1	compositions					778:789	well-balanced essential amino acid compositions	743:789	well-balanced essential amino acid compositions	743:789	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	3	46	theme	Cu	481:482	arg1	glycogen					464:471	glycogen	464:471	glycogen	464:471	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	3	46	theme	Cu	481:482	arg1	contents					491:498	Cu and Zn contents	481:498	Cu and Zn contents	481:498	The results showed that females had higher glycogen, lipid, Cu and Zn contents than males, while males had higher protein and taurine contents than females at maturity, which might be related to special meiosis pattern of eggs and less energy was required for female gametogenesis.					
35961171	4	47	theme	essential	757:765	arg1	compositions					778:789	well-balanced essential amino acid compositions	743:789	well-balanced essential amino acid compositions	743:789	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	0	48	theme	metals	64:69	arg1	Comparison					0:9	Comparison	0:9	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.	0:145	Comparison of biochemical composition, nutritional quality, and metals concentrations between males and females of three different Crassostrea sp.					
35961171	6	49	theme	reliable	971:978	arg1	basis					1017:1021	a reliable and refined theoretical and research basis	969:1021	a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp.	969:1145	These results provide a reliable and refined theoretical and research basis for revealing the nutritional quality, extracting beneficial ingredients, and developing functional food of Crassostrea sp., and provide data support for the sex-regulated breeding of oysters.					
35961171	4	50	theme	acid	773:776	arg1	compositions					778:789	well-balanced essential amino acid compositions	743:789	well-balanced essential amino acid compositions	743:789	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	5	51	theme	males	929:933	arg1	higher					939:944	higher	939:944	higher	939:944	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	5	51	theme	males	929:933	arg1	quality					918:924	the nutritional quality	902:924	the nutritional quality of males	902:933	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	4	52	theme	amino	767:771	arg1	compositions					778:789	well-balanced essential amino acid compositions	743:789	well-balanced essential amino acid compositions	743:789	In addition, both males and females had well-balanced essential amino acid compositions.					
35961171	5	53	theme	males	833:837	arg1	higher					857:862	higher	857:862	higher	857:862	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
35961171	5	53	theme	males	833:837	arg1	ratio					824:828	The omega-3: omega-6 (n-3: n-6) ratio	792:828	The omega-3: omega-6 (n-3: n-6) ratio of males	792:837	The omega-3: omega-6 (n-3: n-6) ratio of males was significantly higher than that of females, indicating that the nutritional quality of males was higher.					
36572083	6	0	theme	specific	1077:1084	arg1	capacitance					1086:1096	a high volumetric specific capacitance	1059:1096	a high volumetric specific capacitance	1059:1096	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	2	1	theme	oxide	393:397	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	1	theme	oxide	393:397	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	6	2	theme	high	1061:1064	arg1	capacitance					1086:1096	a high volumetric specific capacitance	1059:1096	a high volumetric specific capacitance	1059:1096	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	2	3	theme	graphene	384:391	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	3	theme	graphene	384:391	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	5	4	theme	nanofiber	986:994	arg1	membranes					932:940	two RCC composite membranes	914:940	two RCC composite membranes	914:940	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	4	theme	nanofiber	986:994	arg1	membrane					996:1003	a porous cellulose nanofiber membrane	967:1003	a porous cellulose nanofiber membrane	967:1003	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	3	5	theme	composite	555:563	arg1	membranes					565:573	the RCC composite membranes	547:573	the RCC composite membranes	547:573	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	3	6	theme	better	585:590	arg1	properties					603:612	better mechanical properties	585:612	better mechanical properties	585:612	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	4	7	theme	high	773:776	arg1	capacitance					758:768	a specific capacitance	747:768	a specific capacitance as high as 171.3 F·cm-3	747:792	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	7	8	from	avenue	1246:1251	arg1	design					1256:1261	design	1256:1261	design of next-generation nanocellulose based, sustainable and flexible energy storage device	1256:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	7	9	theme	sustainable	1303:1313	arg1	device					1343:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	3	10	theme	pure	528:531	arg1	membrane					537:544	the pure RGO membrane	524:544	the pure RGO membrane	524:544	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	5	11	theme	cellulose	976:984	arg1	membranes					932:940	two RCC composite membranes	914:940	two RCC composite membranes	914:940	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	11	theme	cellulose	976:984	arg1	membrane					996:1003	a porous cellulose nanofiber membrane	967:1003	a porous cellulose nanofiber membrane	967:1003	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	4	12	theme	composite	718:726	arg1	membrane					728:735	the RCC composite membrane	710:735	the RCC composite membrane	710:735	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	2	13	theme	reduced	376:382	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	13	theme	reduced	376:382	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	1	14	with	nanomaterial	153:164	arg1	properties					230:239	excellent mechanical properties	209:239	excellent mechanical properties	209:239	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	1	14	with	nanomaterial	153:164	arg1	biodegradability					187:202	biodegradability	187:202	biodegradability	187:202	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	1	14	with	nanomaterial	153:164	arg1	sustainability					171:184	sustainability	171:184	sustainability	171:184	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	4	15	theme	synergistic	658:668	arg1	effect					670:675	the synergistic effect	654:675	the synergistic effect of nanocellulose and RGO sheets	654:707	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	2	16	theme	/cellulose	404:413	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	16	theme	/cellulose	404:413	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	17	theme	nanofiber	437:445	arg1	membrane					463:470	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	5	18	theme	nanocellulose-based	811:829	arg1	FASC					882:885	FASC	882:885	FASC	882:885	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	18	theme	nanocellulose-based	811:829	arg1	supercapacitor					866:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor	809:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC)	809:886	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	3	19	theme	RCC	551:553	arg1	membranes					565:573	the RCC composite membranes	547:573	the RCC composite membranes	547:573	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	1	20	theme	excellent	209:217	arg1	properties					230:239	excellent mechanical properties	209:239	excellent mechanical properties	209:239	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	6	21	theme	3.7 mW·h·cm-3	1151:1163	arg1	density					1140:1146	a satisfactory energy density	1118:1146	a satisfactory energy density of 3.7 mW·h·cm-3	1118:1163	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	6	21	theme	3.7 mW·h·cm-3	1151:1163	arg1	164.3 F·cm-3					1101:1112	164.3 F·cm-3	1101:1112	164.3 F·cm-3	1101:1112	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	3	22	theme	mechanical	592:601	arg1	properties					603:612	better mechanical properties	585:612	better mechanical properties	585:612	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	7	23	theme	storage	1335:1341	arg1	device					1343:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	1	24	theme	mechanical	219:228	arg1	properties					230:239	excellent mechanical properties	209:239	excellent mechanical properties	209:239	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	0	25	theme	Nanocellulose-based	0:18	arg1	electrodes					20:29	Nanocellulose-based electrodes	0:29	Nanocellulose-based electrodes	0:29	Nanocellulose-based electrodes and separator toward sustainable and flexible all-solid-state supercapacitor.					
36572083	6	26	theme	fabricated	1030:1039	arg1	FASC					1041:1044	This fabricated FASC	1025:1044	This fabricated FASC	1025:1044	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	4	27	theme	RGO	698:700	arg1	sheets					702:707	nanocellulose and RGO sheets	680:707	nanocellulose and RGO sheets	680:707	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	4	28	theme	sheets	702:707	arg1	effect					670:675	the synergistic effect	654:675	the synergistic effect of nanocellulose and RGO sheets	654:707	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	5	29	theme	flexible	841:848	arg1	FASC					882:885	FASC	882:885	FASC	882:885	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	29	theme	flexible	841:848	arg1	supercapacitor					866:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor	809:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC)	809:886	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	2	30	theme	composite	453:461	arg1	membrane					463:470	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	1	31	theme	flexible	317:324	arg1	devices					357:363	the flexible electrochemical energy storage devices	313:363	the flexible electrochemical energy storage devices	313:363	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	3	32	theme	RGO	533:535	arg1	membrane					537:544	the pure RGO membrane	524:544	the pure RGO membrane	524:544	Compared to the pure RGO membrane, the RCC composite membranes exhibited better mechanical properties and hydrophilicity.					
36572083	4	33	theme	RCC	714:716	arg1	membrane					728:735	the RCC composite membrane	710:735	the RCC composite membrane	710:735	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	0	34	theme	sustainable	52:62	arg1	supercapacitor					93:106	sustainable and flexible all-solid-state supercapacitor	52:106	sustainable and flexible all-solid-state supercapacitor	52:106	Nanocellulose-based electrodes and separator toward sustainable and flexible all-solid-state supercapacitor.					
36572083	1	35	theme	electrochemical	326:340	arg1	devices					357:363	the flexible electrochemical energy storage devices	313:363	the flexible electrochemical energy storage devices	313:363	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	1	36	from	systems	287:293	arg1	devices					357:363	the flexible electrochemical energy storage devices	313:363	the flexible electrochemical energy storage devices	313:363	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	6	37	theme	other	1194:1198	arg1	FASCs					1200:1204	many other FASCs	1189:1204	many other FASCs ever reported	1189:1218	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	5	38	theme	composite	922:930	arg1	membranes					932:940	two RCC composite membranes	914:940	two RCC composite membranes	914:940	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	38	theme	composite	922:930	arg1	electrodes					952:961	electrodes	952:961	electrodes	952:961	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	38	theme	composite	922:930	arg1	membrane					996:1003	a porous cellulose nanofiber membrane	967:1003	a porous cellulose nanofiber membrane	967:1003	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	4	39	theme	nanocellulose	680:692	arg1	sheets					702:707	nanocellulose and RGO sheets	680:707	nanocellulose and RGO sheets	680:707	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	2	40	theme	one-pot	496:502	arg1	method					504:509	a one-pot method	494:509	a one-pot method	494:509	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	1	41	theme	energy	342:347	arg1	devices					357:363	the flexible electrochemical energy storage devices	313:363	the flexible electrochemical energy storage devices	313:363	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	5	42	theme	RCC	918:920	arg1	membranes					932:940	two RCC composite membranes	914:940	two RCC composite membranes	914:940	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	42	theme	RCC	918:920	arg1	electrodes					952:961	electrodes	952:961	electrodes	952:961	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	42	theme	RCC	918:920	arg1	membrane					996:1003	a porous cellulose nanofiber membrane	967:1003	a porous cellulose nanofiber membrane	967:1003	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	6	43	theme	volumetric	1066:1075	arg1	capacitance					1086:1096	a high volumetric specific capacitance	1059:1096	a high volumetric specific capacitance	1059:1096	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	6	44	theme	density	1140:1146	arg1	capacitance					1086:1096	a high volumetric specific capacitance	1059:1096	a high volumetric specific capacitance	1059:1096	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	0	45	theme	flexible	68:75	arg1	supercapacitor					93:106	sustainable and flexible all-solid-state supercapacitor	52:106	sustainable and flexible all-solid-state supercapacitor	52:106	Nanocellulose-based electrodes and separator toward sustainable and flexible all-solid-state supercapacitor.					
36572083	1	46	theme	storage	349:355	arg1	devices					357:363	the flexible electrochemical energy storage devices	313:363	the flexible electrochemical energy storage devices	313:363	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	7	47	theme	based	1296:1300	arg1	device					1343:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	1	48	theme	abundant	136:143	arg1	nanomaterial					153:164	the most abundant natural nanomaterial	127:164	the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties	127:239	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	1	48	theme	abundant	136:143	arg1	Nanocellulose					109:121	Nanocellulose	109:121	Nanocellulose	109:121	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	5	49	theme	all-solid-state	850:864	arg1	FASC					882:885	FASC	882:885	FASC	882:885	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	49	theme	all-solid-state	850:864	arg1	supercapacitor					866:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor	809:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC)	809:886	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	7	50	theme	device	1343:1348	arg1	design					1256:1261	design	1256:1261	design of next-generation nanocellulose based, sustainable and flexible energy storage device	1256:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	1	51	theme	natural	145:151	arg1	nanomaterial					153:164	the most abundant natural nanomaterial	127:164	the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties	127:239	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	1	51	theme	natural	145:151	arg1	Nanocellulose					109:121	Nanocellulose	109:121	Nanocellulose	109:121	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	5	52	theme	porous	969:974	arg1	membranes					932:940	two RCC composite membranes	914:940	two RCC composite membranes	914:940	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	52	theme	porous	969:974	arg1	membrane					996:1003	a porous cellulose nanofiber membrane	967:1003	a porous cellulose nanofiber membrane	967:1003	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	6	53	theme	energy	1133:1138	arg1	density					1140:1146	a satisfactory energy density	1118:1146	a satisfactory energy density of 3.7 mW·h·cm-3	1118:1163	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	4	54	theme	specific	749:756	arg1	capacitance					758:768	a specific capacitance	747:768	a specific capacitance as high as 171.3 F·cm-3	747:792	Furthermore, due to the synergistic effect of nanocellulose and RGO sheets, the RCC composite membrane exhibited a specific capacitance as high as 171.3 F·cm-3.					
36572083	6	55	theme	many	1189:1192	arg1	FASCs					1200:1204	many other FASCs	1189:1204	many other FASCs ever reported	1189:1218	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	6	56	theme	164.3 F·cm-3	1101:1112	arg1	capacitance					1086:1096	a high volumetric specific capacitance	1059:1096	a high volumetric specific capacitance	1059:1096	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	6	57	theme	satisfactory	1120:1131	arg1	density					1140:1146	a satisfactory energy density	1118:1146	a satisfactory energy density of 3.7 mW·h·cm-3	1118:1163	This fabricated FASC demonstrated a high volumetric specific capacitance of 164.3 F·cm-3 and a satisfactory energy density of 3.7 mW·h·cm-3, which exceeded that of many other FASCs ever reported.					
36572083	2	58	theme	RGO	400:402	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	58	theme	RGO	400:402	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	59	theme	nanocrystal/cellulose	415:435	arg1	RCC					448:450	RCC	448:450	RCC	448:450	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	2	59	theme	nanocrystal/cellulose	415:435	arg1	nanofiber					437:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber	374:445	a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane	374:470	Herein, a reduced graphene oxide (RGO)/cellulose nanocrystal/cellulose nanofiber (RCC) composite membrane was prepared by using a one-pot method.					
36572083	1	60	theme	modern	269:274	arg1	systems					287:293	modern electronic systems	269:293	modern electronic systems	269:293	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36572083	0	61	theme	all-solid-state	77:91	arg1	supercapacitor					93:106	sustainable and flexible all-solid-state supercapacitor	52:106	sustainable and flexible all-solid-state supercapacitor	52:106	Nanocellulose-based electrodes and separator toward sustainable and flexible all-solid-state supercapacitor.					
36572083	7	62	theme	new	1242:1244	arg1	avenue					1246:1251	a new avenue	1240:1251	a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device	1240:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	5	63	theme	symmetric	831:839	arg1	FASC					882:885	FASC	882:885	FASC	882:885	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	5	63	theme	symmetric	831:839	arg1	supercapacitor					866:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor	809:879	a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC)	809:886	Consequently, a nanocellulose-based symmetric flexible all-solid-state supercapacitor (FASC) was constructed, in which two RCC composite membranes served as electrodes and a porous cellulose nanofiber membrane acted as separator.					
36572083	7	64	theme	energy	1328:1333	arg1	device					1343:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	7	65	theme	flexible	1319:1326	arg1	device					1343:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	next-generation nanocellulose based, sustainable and flexible energy storage device	1266:1348	This work may open a new avenue in design of next-generation nanocellulose based, sustainable and flexible energy storage device.					
36572083	1	66	theme	electronic	276:285	arg1	systems					287:293	modern electronic systems	269:293	modern electronic systems	269:293	Nanocellulose, as the most abundant natural nanomaterial with sustainability, biodegradability, and excellent mechanical properties, has been widely applied in modern electronic systems, particularly, in the flexible electrochemical energy storage devices.					
36890858	7	0	theme	bile	1425:1428	arg1	duct					1430:1433	bile duct	1425:1433	bile duct	1425:1433	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	0	1	link	N-linked	12:19	arg1	Alterations					28:38	N-linked Glycan Alterations	12:38	N-linked Glycan Alterations in Tissue and Serum	12:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	10	2	theme	serum	1979:1983	arg1	biomarkers					1985:1994	serum biomarkers	1979:1994	serum biomarkers that can be used for the noninvasive detection of iCCA	1979:2049	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	3	3	theme	N-glycan	562:569	arg1	structures					571:580	N-glycan structures	562:580	N-glycan structures on glycoproteins	562:597	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	7	4	theme	HCC	1417:1419	arg1	disease					1435:1441	HCC and bile duct disease	1417:1441	HCC and bile duct disease	1417:1441	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	3	5	theme	liver	713:717	arg1	diseases					719:726	liver diseases	713:726	liver diseases	713:726	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	6	6	theme	tumor	1177:1181	arg1	regions					1183:1189	tumor regions	1177:1189	tumor regions annotated on histopathology	1177:1217	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	1	7	theme	reliable	176:183	arg1	biomarkers					196:205	reliable prognostic biomarkers	176:205	reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA)	176:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	7	8	theme	relative	1405:1412	arg1	tissue					1388:1393	iCCA tissue	1383:1393	iCCA tissue	1383:1393	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	9	9	theme	standard	1815:1822	arg1	"					1823:1823	the current "gold standard"	1797:1823	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	1	10	theme	immense	320:326	arg1	potential					328:336	an immense potential	317:336	an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC)	317:431	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	11	theme	biomarkers	196:205	arg1	identification					158:171	the identification	154:171	the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA)	154:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	12	theme	hepatocellular	402:415	arg1	HCC					428:430	HCC	428:430	HCC	428:430	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	12	theme	hepatocellular	402:415	arg1	carcinoma					417:425	hepatocellular carcinoma	402:425	hepatocellular carcinoma (HCC)	402:431	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	5	13	theme	N-glycan	842:849	arg1	modifications					851:863	the N-glycan modifications	838:863	the N-glycan modifications	838:863	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	2	14	theme	cell	556:559	arg1	status					542:547	the status	538:547	the status of the cell	538:559	N-glycosylation is one of the most common post-translational modifications known to be altered based on the status of the cell.					
36890858	7	15	theme	same	1321:1324	arg1	modifications					1335:1347	These same N-glycan modifications	1315:1347	These same N-glycan modifications	1315:1347	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	9	16	theme	CCA	1838:1840	arg1	biomarker					1825:1833	the current "gold standard" biomarker	1797:1833	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	9	16	theme	CCA	1838:1840	arg1	19-9					1791:1794	carbohydrate antigen 19-9	1770:1794	carbohydrate antigen 19-9	1770:1794	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	5	17	with	patients	1066:1073	arg1	n					1124:1124	n = 67	1124:1129	n = 67	1124:1129	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	17	with	patients	1066:1073	arg1	HCC					1086:1088	HCC	1086:1088	HCC	1086:1088	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	17	with	patients	1066:1073	arg1	iCCA					1080:1083	iCCA	1080:1083	iCCA	1080:1083	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	17	with	patients	1066:1073	arg1	disease					1115:1121	benign chronic liver disease	1094:1121	benign chronic liver disease (n = 67)	1094:1130	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	1	18	from	alterations	268:278	arg1	N-glycosylation					283:297	N-glycosylation	283:297	N-glycosylation	283:297	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	5	19	theme	serum	1039:1043	arg1	cohort					1045:1050	one independent serum cohort	1023:1050	one independent serum cohort	1023:1050	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	1	20	theme	intrahepatic	225:236	arg1	iCCA					258:261	iCCA	258:261	iCCA	258:261	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	20	theme	intrahepatic	225:236	arg1	cholangiocarcinoma					238:255	intrahepatic cholangiocarcinoma	225:255	intrahepatic cholangiocarcinoma (iCCA)	225:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	0	21	from	Serum	54:58	arg1	Analysis					0:7	Analysis	0:7	Analysis of N-linked Glycan Alterations in Tissue and Serum	0:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	6	22	theme	in	1151:1152	arg1	analysis					1142:1149	N-glycan analysis	1133:1149	N-glycan analysis in situ	1133:1157	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	6	23	theme	bisected	1237:1244	arg1	structures					1267:1276	bisected fucosylated N-glycan structures	1237:1276	bisected fucosylated N-glycan structures	1237:1276	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	5	24	theme	tissue	934:939	arg1	cohort					962:967	a discovery cohort	950:967	a discovery cohort (n = 104 cases)	950:983	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	24	theme	tissue	934:939	arg1	cohorts					941:947	two tissue cohorts	930:947	two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75)	930:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	24	theme	tissue	934:939	arg1	cohort					1002:1007	a validation cohort	989:1007	a validation cohort (n = 75)	989:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	6	25	theme	N-glycan	1133:1140	arg1	analysis					1142:1149	N-glycan analysis	1133:1149	N-glycan analysis in situ	1133:1157	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	1	26	theme	urgent	138:143	arg1	need					145:148	an urgent need	135:148	an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA)	135:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	6	27	dep	in	1151:1152	arg1	situ					1154:1157	situ	1154:1157	situ	1154:1157	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	9	28	theme	biomarker	1667:1675	arg1	algorithm					1677:1685	this biomarker algorithm	1662:1685	this biomarker algorithm	1662:1685	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	0	29	theme	Promising	68:76	arg1	Biomarkers					78:87	Promising Biomarkers	68:87	Promising Biomarkers for Intrahepatic Cholangiocarcinoma	68:123	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	0	30	from	Analysis	0:7	arg1	Serum					54:58	Serum	54:58	Serum	54:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	0	30	from	Analysis	0:7	arg1	Tissue					43:48	Tissue	43:48	Tissue	43:48	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	5	31	dep	cohorts	941:947	arg1	cohort					962:967	a discovery cohort	950:967	a discovery cohort (n = 104 cases)	950:983	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	31	dep	cohorts	941:947	arg1	cohorts					941:947	two tissue cohorts	930:947	two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75)	930:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	31	dep	cohorts	941:947	arg1	n					1010:1010	n = 75	1010:1015	n = 75	1010:1015	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	31	dep	cohorts	941:947	arg1	cohort					1002:1007	a validation cohort	989:1007	a validation cohort (n = 75)	989:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	31	dep	cohorts	941:947	arg1	cases					978:982	n = 104 cases	970:982	n = 104 cases	970:982	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	6	32	theme	tumor	1300:1304	arg1	regions					1306:1312	iCCA tumor regions	1295:1312	iCCA tumor regions	1295:1312	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	1	33	theme	many	378:381	arg1	cancers					383:389	many cancers	378:389	many cancers	378:389	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	33	theme	many	378:381	arg1	carcinoma					417:425	hepatocellular carcinoma	402:425	hepatocellular carcinoma (HCC)	402:431	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	5	34	theme	=	972:972	arg1	cohort					962:967	a discovery cohort	950:967	a discovery cohort (n = 104 cases)	950:983	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	34	theme	=	972:972	arg1	cases					978:982	n = 104 cases	970:982	n = 104 cases	970:982	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	0	35	from	Tissue	43:48	arg1	Analysis					0:7	Analysis	0:7	Analysis of N-linked Glycan Alterations in Tissue and Serum	0:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	0	36	from	Alterations	28:38	arg1	Serum					54:58	Serum	54:58	Serum	54:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	0	36	from	Alterations	28:38	arg1	Tissue					43:48	Tissue	43:48	Tissue	43:48	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	9	37	from	specificity	1722:1732	arg1	sensitivity					1702:1712	the sensitivity	1698:1712	the sensitivity (at 90% specificity) of iCCA detection	1698:1751	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	5	38	theme	discovery	952:960	arg1	cohort					962:967	a discovery cohort	950:967	a discovery cohort (n = 104 cases)	950:983	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	38	theme	discovery	952:960	arg1	cohorts					941:947	two tissue cohorts	930:947	two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75)	930:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	38	theme	discovery	952:960	arg1	cases					978:982	n = 104 cases	970:982	n = 104 cases	970:982	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	9	39	theme	%	1720:1720	arg1	specificity					1722:1732	90% specificity	1718:1732	90% specificity	1718:1732	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	0	40	theme	N-linked	12:19	arg1	Alterations					28:38	N-linked Glycan Alterations	12:38	N-linked Glycan Alterations in Tissue and Serum	12:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	3	41	theme	residues	669:676	arg1	addition					628:635	addition	628:635	addition	628:635	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	3	41	theme	residues	669:676	arg1	removal					640:646	removal	640:646	removal	640:646	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	0	42	theme	Alterations	28:38	arg1	Analysis					0:7	Analysis	0:7	Analysis of N-linked Glycan Alterations in Tissue and Serum	0:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	1	43	with	patients	211:218	arg1	iCCA					258:261	iCCA	258:261	iCCA	258:261	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	1	43	with	patients	211:218	arg1	cholangiocarcinoma					238:255	intrahepatic cholangiocarcinoma	225:255	intrahepatic cholangiocarcinoma (iCCA)	225:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	2	44	theme	post-translational	476:493	arg1	modifications					495:507	the most common post-translational modifications	460:507	the most common post-translational modifications known to be altered based on the status of the cell	460:559	N-glycosylation is one of the most common post-translational modifications known to be altered based on the status of the cell.					
36890858	3	45	theme	specific	651:658	arg1	residues					669:676	specific N-glycan residues	651:676	specific N-glycan residues	651:676	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	5	46	theme	chronic	1101:1107	arg1	n					1124:1124	n = 67	1124:1129	n = 67	1124:1129	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	46	theme	chronic	1101:1107	arg1	disease					1115:1121	benign chronic liver disease	1094:1121	benign chronic liver disease (n = 67)	1094:1130	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	7	47	theme	primary	1454:1460	arg1	PSC					1486:1488	PSC	1486:1488	PSC	1486:1488	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	7	47	theme	primary	1454:1460	arg1	P					1492:1492	P < 0.0001	1492:1501	P < 0.0001	1492:1501	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	7	47	theme	primary	1454:1460	arg1	cholangitis					1473:1483	primary sclerosing cholangitis	1454:1483	primary sclerosing cholangitis (PSC) (P < 0.0001)	1454:1502	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	5	48	theme	=	1012:1012	arg1	n					1010:1010	n = 75	1010:1015	n = 75	1010:1015	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	48	theme	=	1012:1012	arg1	cohort					1002:1007	a validation cohort	989:1007	a validation cohort (n = 75)	989:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	8	49	theme	N-glycan	1505:1512	arg1	modifications					1514:1526	N-glycan modifications	1505:1526	N-glycan modifications identified in iCCA tissue and serum	1505:1562	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	8	50	used	used	1613:1616	arg2	algorithm					1589:1597	an algorithm	1586:1597	an algorithm that could be used as a biomarker of iCCA	1586:1639	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	8	50	used	used	1613:1616	arg2	biomarker					1623:1631	a biomarker	1621:1631	a biomarker of iCCA	1621:1639	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	6	51	gly	fucosylated	1246:1256	arg1	structures					1267:1276	bisected fucosylated N-glycan structures	1237:1276	bisected fucosylated N-glycan structures	1237:1276	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	9	52	theme	iCCA	1738:1741	arg1	detection					1743:1751	iCCA detection	1738:1751	iCCA detection	1738:1751	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	7	53	theme	duct	1430:1433	arg1	disease					1435:1441	HCC and bile duct disease	1417:1441	HCC and bile duct disease	1417:1441	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	5	54	theme	validation	991:1000	arg1	cohorts					941:947	two tissue cohorts	930:947	two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75)	930:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	54	theme	validation	991:1000	arg1	n					1010:1010	n = 75	1010:1015	n = 75	1010:1015	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	54	theme	validation	991:1000	arg1	cohort					1002:1007	a validation cohort	989:1007	a validation cohort (n = 75)	989:1016	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	9	55	theme	antigen	1783:1789	arg1	19-9					1791:1794	carbohydrate antigen 19-9	1770:1794	carbohydrate antigen 19-9	1770:1794	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	9	55	theme	antigen	1783:1789	arg1	biomarker					1825:1833	the current "gold standard" biomarker	1797:1833	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	8	56	theme	iCCA	1542:1545	arg1	tissue					1547:1552	iCCA tissue	1542:1552	iCCA tissue	1542:1552	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	3	57	attach	linked	703:708	arg1	diseases					719:726	liver diseases	713:726	liver diseases	713:726	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	3	57	attach	linked	703:708	arg2	some					679:682	some	679:682	some	679:682	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	3	57	attach	linked	703:708	arg2	residues					669:676	specific N-glycan residues	651:676	specific N-glycan residues	651:676	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	9	58	theme	current	1801:1807	arg1	"					1823:1823	the current "gold standard"	1797:1823	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	8	59	used	used	1569:1572	arg2	modifications					1514:1526	N-glycan modifications	1505:1526	N-glycan modifications identified in iCCA tissue and serum	1505:1562	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	9	60	theme	detection	1743:1751	arg1	sensitivity					1702:1712	the sensitivity	1698:1712	the sensitivity (at 90% specificity) of iCCA detection	1698:1751	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	7	61	theme	iCCA	1383:1386	arg1	tissue					1388:1393	iCCA tissue	1383:1393	iCCA tissue	1383:1393	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	9	62	theme	gold	1810:1813	arg1	"					1823:1823	the current "gold standard"	1797:1823	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	10	63	used	used	2008:2011	arg2	biomarkers					1985:1994	serum biomarkers	1979:1994	serum biomarkers that can be used for the noninvasive detection of iCCA	1979:2049	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	1	64	theme	prognostic	185:194	arg1	biomarkers					196:205	reliable prognostic biomarkers	176:205	reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA)	176:262	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	9	65	theme	"	1823:1823	arg1	biomarker					1825:1833	the current "gold standard" biomarker	1797:1833	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	9	65	theme	"	1823:1823	arg1	19-9					1791:1794	carbohydrate antigen 19-9	1770:1794	carbohydrate antigen 19-9	1770:1794	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	8	66	theme	iCCA	1636:1639	arg1	biomarker					1623:1631	a biomarker	1621:1631	a biomarker of iCCA	1621:1639	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	8	66	theme	iCCA	1636:1639	arg1	algorithm					1589:1597	an algorithm	1586:1597	an algorithm that could be used as a biomarker of iCCA	1586:1639	N-glycan modifications identified in iCCA tissue and serum were used to generate an algorithm that could be used as a biomarker of iCCA.					
36890858	10	67	theme	iCCA	2046:2049	arg1	detection					2033:2041	the noninvasive detection	2017:2041	the noninvasive detection of iCCA	2017:2049	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	5	68	theme	independent	1027:1037	arg1	cohort					1045:1050	one independent serum cohort	1023:1050	one independent serum cohort	1023:1050	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	7	69	theme	N-glycan	1326:1333	arg1	modifications					1335:1347	These same N-glycan modifications	1315:1347	These same N-glycan modifications	1315:1347	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	10	70	theme	N-glycan	1881:1888	arg1	alterations					1890:1900	the N-glycan alterations	1877:1900	the N-glycan alterations that occur directly in iCCA tissue	1877:1935	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	6	71	theme	fucosylated	1246:1256	arg1	structures					1267:1276	bisected fucosylated N-glycan structures	1237:1276	bisected fucosylated N-glycan structures	1237:1276	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	3	72	gly	glycoproteins	585:597	arg1	glycoproteins					585:597	glycoproteins	585:597	glycoproteins	585:597	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	3	73	from	structures	571:580	arg1	glycoproteins					585:597	glycoproteins	585:597	glycoproteins	585:597	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	1	74	theme	diagnostic	352:361	arg1	strategies					363:372	diagnostic strategies	352:372	diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC)	352:431	There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies for many cancers, including hepatocellular carcinoma (HCC).					
36890858	7	75	theme	<	1494:1494	arg1	P					1492:1492	P < 0.0001	1492:1501	P < 0.0001	1492:1501	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	7	75	theme	<	1494:1494	arg1	cholangitis					1473:1483	primary sclerosing cholangitis	1454:1483	primary sclerosing cholangitis (PSC) (P < 0.0001)	1454:1502	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	0	76	theme	Intrahepatic	93:104	arg1	Cholangiocarcinoma					106:123	Intrahepatic Cholangiocarcinoma	93:123	Intrahepatic Cholangiocarcinoma	93:123	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	5	77	theme	n	970:970	arg1	cohort					962:967	a discovery cohort	950:967	a discovery cohort (n = 104 cases)	950:983	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	77	theme	n	970:970	arg1	cases					978:982	n = 104 cases	970:982	n = 104 cases	970:982	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	10	78	dep	Significance	1843:1854	arg1	elucidates					1866:1875	elucidates	1866:1875	elucidates the N-glycan alterations that occur directly in iCCA tissue	1866:1935	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	10	78	dep	Significance	1843:1854	arg1	utilizes					1941:1948	utilizes	1941:1948	utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA	1941:2049	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	10	79	theme	iCCA	1925:1928	arg1	tissue					1930:1935	iCCA tissue	1925:1935	iCCA tissue	1925:1935	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	6	80	theme	iCCA	1295:1298	arg1	regions					1306:1312	iCCA tumor regions	1295:1312	iCCA tumor regions	1295:1312	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	3	81	dep	addition	628:635	arg1	the					624:626	the	624:626	the	624:626	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	4	82	theme	N-glycan	769:776	arg1	alterations					778:788	the N-glycan alterations	765:788	the N-glycan alterations that are associated with iCCA	765:818	However, little is known concerning the N-glycan alterations that are associated with iCCA.					
36890858	9	83	theme	90	1718:1719	arg1	%					1720:1720	%	1720:1720	%	1720:1720	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	0	84	theme	Glycan	21:26	arg1	Alterations					28:38	N-linked Glycan Alterations	12:38	N-linked Glycan Alterations in Tissue and Serum	12:58	Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma.					
36890858	3	85	theme	N-glycan	660:667	arg1	residues					669:676	specific N-glycan residues	651:676	specific N-glycan residues	651:676	N-glycan structures on glycoproteins can be modified based on the addition or removal of specific N-glycan residues, some of which have been linked to liver diseases.					
36890858	10	86	theme	noninvasive	2021:2031	arg1	detection					2033:2041	the noninvasive detection	2017:2041	the noninvasive detection of iCCA	2017:2049	Significance This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.					
36890858	5	87	theme	=	1126:1126	arg1	n					1124:1124	n = 67	1124:1129	n = 67	1124:1129	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	87	theme	=	1126:1126	arg1	disease					1115:1121	benign chronic liver disease	1094:1121	benign chronic liver disease (n = 67)	1094:1130	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	2	88	theme	modifications	495:507	arg1	one					453:455	one	453:455	one	453:455	N-glycosylation is one of the most common post-translational modifications known to be altered based on the status of the cell.					
36890858	2	88	theme	modifications	495:507	arg1	modifications					495:507	the most common post-translational modifications	460:507	the most common post-translational modifications known to be altered based on the status of the cell	460:559	N-glycosylation is one of the most common post-translational modifications known to be altered based on the status of the cell.					
36890858	5	89	theme	benign	1094:1099	arg1	n					1124:1124	n = 67	1124:1129	n = 67	1124:1129	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	89	theme	benign	1094:1099	arg1	disease					1115:1121	benign chronic liver disease	1094:1121	benign chronic liver disease (n = 67)	1094:1130	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	2	90	theme	common	469:474	arg1	modifications					495:507	the most common post-translational modifications	460:507	the most common post-translational modifications known to be altered based on the status of the cell	460:559	N-glycosylation is one of the most common post-translational modifications known to be altered based on the status of the cell.					
36890858	5	91	theme	liver	1109:1113	arg1	n					1124:1124	n = 67	1124:1129	n = 67	1124:1129	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	5	91	theme	liver	1109:1113	arg1	disease					1115:1121	benign chronic liver disease	1094:1121	benign chronic liver disease (n = 67)	1094:1130	We characterized the N-glycan modifications quantitatively and qualitatively in three cohorts, consisting of two tissue cohorts: a discovery cohort (n = 104 cases) and a validation cohort (n = 75), and one independent serum cohort consisting of patients with iCCA, HCC, or benign chronic liver disease (n = 67).					
36890858	7	92	theme	sclerosing	1462:1471	arg1	PSC					1486:1488	PSC	1486:1488	PSC	1486:1488	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	7	92	theme	sclerosing	1462:1471	arg1	P					1492:1492	P < 0.0001	1492:1501	P < 0.0001	1492:1501	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	7	92	theme	sclerosing	1462:1471	arg1	cholangitis					1473:1483	primary sclerosing cholangitis	1454:1483	primary sclerosing cholangitis (PSC) (P < 0.0001)	1454:1502	These same N-glycan modifications were significantly upregulated in iCCA tissue and serum relative to HCC and bile duct disease, including primary sclerosing cholangitis (PSC) (P < 0.0001).					
36890858	6	93	theme	N-glycan	1258:1265	arg1	structures					1267:1276	bisected fucosylated N-glycan structures	1237:1276	bisected fucosylated N-glycan structures	1237:1276	N-glycan analysis in situ was correlated to tumor regions annotated on histopathology and revealed that bisected fucosylated N-glycan structures were specific to iCCA tumor regions.					
36890858	9	94	theme	carbohydrate	1770:1781	arg1	19-9					1791:1794	carbohydrate antigen 19-9	1770:1794	carbohydrate antigen 19-9	1770:1794	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
36890858	9	94	theme	carbohydrate	1770:1781	arg1	biomarker					1825:1833	the current "gold standard" biomarker	1797:1833	the current "gold standard" biomarker of CCA	1797:1840	We demonstrate that this biomarker algorithm quadrupled the sensitivity (at 90% specificity) of iCCA detection as compared with carbohydrate antigen 19-9, the current "gold standard" biomarker of CCA.					
35318077	0	0	theme	intestinal	94:103	arg1	Cldn5					105:109	intestinal Cldn5	94:109	intestinal Cldn5	94:109	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	6	1	theme	microbiota	836:845	arg1	composition					847:857	the gut microbiota composition	828:857	the gut microbiota composition	828:857	Further analysis using 16S rDNA sequencing suggested that ASP could shape the gut microbiota composition.					
35318077	5	2	theme	pro-inflammatory	676:691	arg1	factors					693:699	pro-inflammatory factors	676:699	pro-inflammatory factors	676:699	Results showed that ASP could reduce joint swelling and significantly inhibit anti-CII-antibodies and pro-inflammatory factors in RA, H group showed the best treatment among them.					
35318077	8	3	theme	RA-induced	1117:1126	arg1	dysfunction					1139:1149	RA-induced intestinal dysfunction	1117:1149	RA-induced intestinal dysfunction	1117:1149	The colonic transcriptome showed that ASP could restore RA-induced intestinal dysfunction, such as tight junction disarrangement, by upregulating Cldn5.					
35318077	4	4	theme	Angelica	484:491	arg1	ASP					518:520	ASP	518:520	ASP	518:520	In this study, the collagen-induced rats were administrated with Angelica sinensis polysaccharide (ASP) at 200 mg/kg (L), 400 mg/kg (M), or 800 mg/kg (H).					
35318077	4	4	theme	Angelica	484:491	arg1	polysaccharide					502:515	Angelica sinensis polysaccharide	484:515	Angelica sinensis polysaccharide (ASP)	484:521	In this study, the collagen-induced rats were administrated with Angelica sinensis polysaccharide (ASP) at 200 mg/kg (L), 400 mg/kg (M), or 800 mg/kg (H).					
35318077	10	5	theme	gene	1466:1469	arg1	expression					1471:1480	gene expression	1466:1480	gene expression	1466:1480	Our results suggested that ASP improved RA by regulating gut microbiota and gene expression, revealing a positive relationship between dietary patterns and RA.					
35318077	0	6	theme	Cldn5	105:109	arg1	expression					80:89	the expression	76:89	the expression of intestinal Cldn5, Slit3 and Rgs18	76:126	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	8	7	theme	junction	1166:1173	arg1	disarrangement					1175:1188	tight junction disarrangement	1160:1188	tight junction disarrangement	1160:1188	The colonic transcriptome showed that ASP could restore RA-induced intestinal dysfunction, such as tight junction disarrangement, by upregulating Cldn5.					
35318077	5	8	theme	best	727:730	arg1	treatment					732:740	the best treatment	723:740	the best treatment among them	723:751	Results showed that ASP could reduce joint swelling and significantly inhibit anti-CII-antibodies and pro-inflammatory factors in RA, H group showed the best treatment among them.					
35318077	0	9	theme	Slit3	112:116	arg1	expression					80:89	the expression	76:89	the expression of intestinal Cldn5, Slit3 and Rgs18	76:126	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	9	10	theme	Slit3	1312:1316	arg1	expression					1298:1307	the expression	1294:1307	the expression of Slit3 and Rgs18	1294:1326	The balance between osteoblasts and osteoclasts might be modified by regulating the expression of Slit3 and Rgs18 to alleviate RA, which may be correlated with gut microbiota.					
35318077	10	11	theme	gut	1447:1449	arg1	microbiota					1451:1460	gut microbiota	1447:1460	gut microbiota	1447:1460	Our results suggested that ASP improved RA by regulating gut microbiota and gene expression, revealing a positive relationship between dietary patterns and RA.					
35318077	7	12	theme	key	868:870	arg1	norank_f__Oscillospiraceae					947:972	norank_f__Oscillospiraceae	947:972	norank_f__Oscillospiraceae	947:972	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	12	theme	key	868:870	arg1	norank_f__Desulfovibrionaceae					979:1007	norank_f__Desulfovibrionaceae	979:1007	norank_f__Desulfovibrionaceae	979:1007	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	12	theme	key	868:870	arg1	Lactobacillus					932:944	Lactobacillus	932:944	Lactobacillus	932:944	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	12	theme	key	868:870	arg1	bacteria					872:879	Several key bacteria	860:879	Several key bacteria	860:879	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	12	theme	key	868:870	arg1	norank_f__norank_o__Clostridia_UCG-014					892:929	norank_f__norank_o__Clostridia_UCG-014	892:929	norank_f__norank_o__Clostridia_UCG-014	892:929	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	8	13	theme	tight	1160:1164	arg1	disarrangement					1175:1188	tight junction disarrangement	1160:1188	tight junction disarrangement	1160:1188	The colonic transcriptome showed that ASP could restore RA-induced intestinal dysfunction, such as tight junction disarrangement, by upregulating Cldn5.					
35318077	3	14	theme	RA	415:416	arg1	improvement					400:410	the improvement	396:410	the improvement of RA	396:416	Indeed, non-starch polysaccharides (NSPs) were known to be related to the improvement of RA.					
35318077	0	15	theme	sinensis	9:16	arg1	polysaccharide					18:31	Angelica sinensis polysaccharide	0:31	Angelica sinensis polysaccharide	0:31	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	4	16	theme	collagen-induced	438:453	arg1	rats					455:458	the collagen-induced rats	434:458	the collagen-induced rats	434:458	In this study, the collagen-induced rats were administrated with Angelica sinensis polysaccharide (ASP) at 200 mg/kg (L), 400 mg/kg (M), or 800 mg/kg (H).					
35318077	7	17	theme	RA	1057:1058	arg1	development					1042:1052	the development	1038:1052	the development of RA	1038:1058	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	0	18	theme	Angelica	0:7	arg1	polysaccharide					18:31	Angelica sinensis polysaccharide	0:31	Angelica sinensis polysaccharide	0:31	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	9	19	theme	Rgs18	1322:1326	arg1	expression					1298:1307	the expression	1294:1307	the expression of Slit3 and Rgs18	1294:1326	The balance between osteoblasts and osteoclasts might be modified by regulating the expression of Slit3 and Rgs18 to alleviate RA, which may be correlated with gut microbiota.					
35318077	10	20	theme	dietary	1525:1531	arg1	patterns					1533:1540	dietary patterns	1525:1540	dietary patterns	1525:1540	Our results suggested that ASP improved RA by regulating gut microbiota and gene expression, revealing a positive relationship between dietary patterns and RA.					
35318077	8	21	theme	intestinal	1128:1137	arg1	dysfunction					1139:1149	RA-induced intestinal dysfunction	1117:1149	RA-induced intestinal dysfunction	1117:1149	The colonic transcriptome showed that ASP could restore RA-induced intestinal dysfunction, such as tight junction disarrangement, by upregulating Cldn5.					
35318077	5	22	theme	joint	611:615	arg1	swelling					617:624	joint swelling	611:624	joint swelling	611:624	Results showed that ASP could reduce joint swelling and significantly inhibit anti-CII-antibodies and pro-inflammatory factors in RA, H group showed the best treatment among them.					
35318077	7	23	theme	Several	860:866	arg1	norank_f__Oscillospiraceae					947:972	norank_f__Oscillospiraceae	947:972	norank_f__Oscillospiraceae	947:972	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	23	theme	Several	860:866	arg1	norank_f__Desulfovibrionaceae					979:1007	norank_f__Desulfovibrionaceae	979:1007	norank_f__Desulfovibrionaceae	979:1007	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	23	theme	Several	860:866	arg1	Lactobacillus					932:944	Lactobacillus	932:944	Lactobacillus	932:944	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	23	theme	Several	860:866	arg1	bacteria					872:879	Several key bacteria	860:879	Several key bacteria	860:879	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	7	23	theme	Several	860:866	arg1	norank_f__norank_o__Clostridia_UCG-014					892:929	norank_f__norank_o__Clostridia_UCG-014	892:929	norank_f__norank_o__Clostridia_UCG-014	892:929	Several key bacteria, including norank_f__norank_o__Clostridia_UCG-014, Lactobacillus, norank_f__Oscillospiraceae, and norank_f__Desulfovibrionaceae, were found to be related to the development of RA.					
35318077	1	24	theme	autoimmune	184:193	arg1	disease					195:201	an autoimmune disease	181:201	an autoimmune disease with a high incidence	181:223	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	1	24	theme	autoimmune	184:193	arg1	arthritis					163:171	Rheumatoid arthritis	152:171	Rheumatoid arthritis (RA)	152:176	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	0	25	theme	Rgs18	122:126	arg1	expression					80:89	the expression	76:89	the expression of intestinal Cldn5, Slit3 and Rgs18	76:126	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	5	26	theme	H	708:708	arg1	group					710:714	H group	708:714	H group	708:714	Results showed that ASP could reduce joint swelling and significantly inhibit anti-CII-antibodies and pro-inflammatory factors in RA, H group showed the best treatment among them.					
35318077	8	27	theme	colonic	1065:1071	arg1	transcriptome					1073:1085	The colonic transcriptome	1061:1085	The colonic transcriptome	1061:1085	The colonic transcriptome showed that ASP could restore RA-induced intestinal dysfunction, such as tight junction disarrangement, by upregulating Cldn5.					
35318077	2	28	theme	Recent	226:231	arg1	studies					233:239	Recent studies	226:239	Recent studies	226:239	Recent studies have demonstrated that diet can contribute to the development and progression of RA.					
35318077	0	29	theme	rheumatoid	42:51	arg1	arthritis					53:61	rheumatoid arthritis	42:61	rheumatoid arthritis	42:61	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	0	30	theme	gut	136:138	arg1	microbiota					140:149	gut microbiota	136:149	gut microbiota	136:149	Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota.					
35318077	6	31	theme	rDNA	781:784	arg1	sequencing					786:795	16S rDNA sequencing	777:795	16S rDNA sequencing	777:795	Further analysis using 16S rDNA sequencing suggested that ASP could shape the gut microbiota composition.					
35318077	3	32	theme	non-starch	334:343	arg1	NSPs					362:365	NSPs	362:365	NSPs	362:365	Indeed, non-starch polysaccharides (NSPs) were known to be related to the improvement of RA.					
35318077	3	32	theme	non-starch	334:343	arg1	polysaccharides					345:359	non-starch polysaccharides	334:359	non-starch polysaccharides (NSPs)	334:366	Indeed, non-starch polysaccharides (NSPs) were known to be related to the improvement of RA.					
35318077	4	33	theme	sinensis	493:500	arg1	ASP					518:520	ASP	518:520	ASP	518:520	In this study, the collagen-induced rats were administrated with Angelica sinensis polysaccharide (ASP) at 200 mg/kg (L), 400 mg/kg (M), or 800 mg/kg (H).					
35318077	4	33	theme	sinensis	493:500	arg1	polysaccharide					502:515	Angelica sinensis polysaccharide	484:515	Angelica sinensis polysaccharide (ASP)	484:521	In this study, the collagen-induced rats were administrated with Angelica sinensis polysaccharide (ASP) at 200 mg/kg (L), 400 mg/kg (M), or 800 mg/kg (H).					
35318077	6	34	theme	16S	777:779	arg1	sequencing					786:795	16S rDNA sequencing	777:795	16S rDNA sequencing	777:795	Further analysis using 16S rDNA sequencing suggested that ASP could shape the gut microbiota composition.					
35318077	2	35	dep	development	291:301	arg1	the					287:289	the	287:289	the	287:289	Recent studies have demonstrated that diet can contribute to the development and progression of RA.					
35318077	1	36	with	disease	195:201	arg1	incidence					215:223	a high incidence	208:223	a high incidence	208:223	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	10	37	theme	positive	1495:1502	arg1	relationship					1504:1515	a positive relationship	1493:1515	a positive relationship between dietary patterns and RA	1493:1547	Our results suggested that ASP improved RA by regulating gut microbiota and gene expression, revealing a positive relationship between dietary patterns and RA.					
35318077	6	38	theme	gut	832:834	arg1	composition					847:857	the gut microbiota composition	828:857	the gut microbiota composition	828:857	Further analysis using 16S rDNA sequencing suggested that ASP could shape the gut microbiota composition.					
35318077	2	39	theme	RA	322:323	arg1	development					291:301	development	291:301	development	291:301	Recent studies have demonstrated that diet can contribute to the development and progression of RA.					
35318077	2	39	theme	RA	322:323	arg1	progression					307:317	progression	307:317	progression	307:317	Recent studies have demonstrated that diet can contribute to the development and progression of RA.					
35318077	1	40	theme	high	210:213	arg1	incidence					215:223	a high incidence	208:223	a high incidence	208:223	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	5	41	dep	anti-CII-antibodies	652:670	arg1	showed					716:721	showed	716:721	showed the best treatment among them	716:751	Results showed that ASP could reduce joint swelling and significantly inhibit anti-CII-antibodies and pro-inflammatory factors in RA, H group showed the best treatment among them.					
35318077	6	42	theme	Further	754:760	arg1	analysis					762:769	Further analysis	754:769	Further analysis using 16S rDNA sequencing	754:795	Further analysis using 16S rDNA sequencing suggested that ASP could shape the gut microbiota composition.					
35318077	9	43	theme	gut	1374:1376	arg1	microbiota					1378:1387	gut microbiota	1374:1387	gut microbiota	1374:1387	The balance between osteoblasts and osteoclasts might be modified by regulating the expression of Slit3 and Rgs18 to alleviate RA, which may be correlated with gut microbiota.					
35318077	1	44	theme	Rheumatoid	152:161	arg1	disease					195:201	an autoimmune disease	181:201	an autoimmune disease with a high incidence	181:223	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	1	44	theme	Rheumatoid	152:161	arg1	RA					174:175	RA	174:175	RA	174:175	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35318077	1	44	theme	Rheumatoid	152:161	arg1	arthritis					163:171	Rheumatoid arthritis	152:171	Rheumatoid arthritis (RA)	152:176	Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence.					
35337493	4	0	theme	cellulose	881:889	arg1	chains					891:896	cellulose chains	881:896	cellulose chains	881:896	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	0	1	theme	pine	80:83	arg1	structure					46:54	crystalline structure	34:54	crystalline structure	34:54	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	0	1	theme	pine	80:83	arg1	chemistry					60:68	chemistry	60:68	chemistry	60:68	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	0	2	from	modification	14:25	arg1	decay					98:102	brown-rot decay	88:102	brown-rot decay	88:102	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	3	3	theme	initial	486:492	arg1	increase					494:501	an initial increase	483:501	an initial increase in wood cellulose crystallinity and crystallite width	483:555	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	4	4	theme	cell	977:980	arg1	wall					982:985	the cell wall	973:985	the cell wall	973:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	3	5	theme	early	568:572	arg1	removal					574:580	early removal	568:580	early removal of the more amorphous celluloses	568:613	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	2	6	theme	Masson	268:273	arg1	samples					280:286	Masson pine samples	268:286	Masson pine samples	268:286	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	4	7	theme	wall	982:985	arg1	rearrangement					864:876	the rearrangement	860:876	the rearrangement of cellulose chains	860:896	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	7	theme	wall	982:985	arg1	diffusion					906:914	the diffusion	902:914	the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	902:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	0	8	theme	brown-rot	88:96	arg1	decay					98:102	brown-rot decay	88:102	brown-rot decay	88:102	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	4	9	theme	chains	891:896	arg1	rearrangement					864:876	the rearrangement	860:876	the rearrangement of cellulose chains	860:896	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	9	theme	chains	891:896	arg1	diffusion					906:914	the diffusion	902:914	the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	902:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	3	10	from	increase	494:501	arg1	crystallinity					521:533	wood cellulose crystallinity	506:533	wood cellulose crystallinity	506:533	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	3	10	from	increase	494:501	arg1	width					551:555	crystallite width	539:555	crystallite width	539:555	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	5	11	from	role	1023:1026	arg1	preservation					1128:1139	lignocellulose preservation	1113:1139	lignocellulose preservation	1113:1139	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	11	from	role	1023:1026	arg1	decay					1067:1071	brown-rot decay	1057:1071	brown-rot decay	1057:1071	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	11	from	role	1023:1026	arg1	biorefineries					1145:1157	biorefineries	1145:1157	biorefineries	1145:1157	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	12	theme	lignocellulose	1113:1126	arg1	preservation					1128:1139	lignocellulose preservation	1113:1139	lignocellulose preservation	1113:1139	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	3	13	theme	wood	506:509	arg1	crystallinity					521:533	wood cellulose crystallinity	506:533	wood cellulose crystallinity	506:533	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	2	14	theme	crystalline	369:379	arg1	structure					381:389	the crystalline structure	365:389	the crystalline structure of cellulose	365:402	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	3	15	from	decrease	630:637	arg1	crystallinity					642:654	crystallinity	642:654	crystallinity	642:654	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	3	15	from	decrease	630:637	arg1	size					672:675	crystallite size	660:675	crystallite size	660:675	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	3	16	theme	cellulose	511:519	arg1	crystallinity					521:533	wood cellulose crystallinity	506:533	wood cellulose crystallinity	506:533	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	2	17	theme	wood	432:435	arg1	changes					354:360	changes	354:360	changes in the crystalline structure of cellulose	354:402	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	2	17	theme	wood	432:435	arg1	composition					417:427	chemical composition	408:427	chemical composition of wood in brown-rot decay	408:454	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	4	18	from	changes	849:855	arg1	rearrangement					864:876	the rearrangement	860:876	the rearrangement of cellulose chains	860:896	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	18	from	changes	849:855	arg1	diffusion					906:914	the diffusion	902:914	the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	902:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	5	19	from	application	1098:1108	arg1	preservation					1128:1139	lignocellulose preservation	1113:1139	lignocellulose preservation	1113:1139	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	19	from	application	1098:1108	arg1	decay					1067:1071	brown-rot decay	1057:1071	brown-rot decay	1057:1071	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	19	from	application	1098:1108	arg1	biorefineries					1145:1157	biorefineries	1145:1157	biorefineries	1145:1157	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	0	20	theme	Non-enzymatic	0:12	arg1	modification					14:25	Non-enzymatic modification	0:25	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.	0:103	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	4	21	theme	amorphous	715:723	arg1	cellulose					725:733	amorphous cellulose	715:733	amorphous cellulose	715:733	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	22	theme	polysaccharides	950:964	arg1	rearrangement					864:876	the rearrangement	860:876	the rearrangement of cellulose chains	860:896	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	22	theme	polysaccharides	950:964	arg1	diffusion					906:914	the diffusion	902:914	the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	902:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	2	23	theme	pine	275:278	arg1	samples					280:286	Masson pine samples	268:286	Masson pine samples	268:286	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	2	24	theme	chemical	408:415	arg1	composition					417:427	chemical composition	408:427	chemical composition of wood in brown-rot decay	408:454	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	3	25	dep	resulted	471:478	arg1	followed					616:623	followed	616:623	followed by a decrease in crystallinity and crystallite size	616:675	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	1	26	theme	Masson	105:110	arg1	pine					112:115	Masson pine	105:115	Masson pine	105:115	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	5	27	theme	system	1047:1052	arg1	role					1023:1026	the role	1019:1026	the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries	1019:1157	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	5	27	theme	system	1047:1052	arg1	application					1098:1108	its potential application	1084:1108	the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries	1019:1157	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	2	28	theme	cellulose	394:402	arg1	structure					381:389	the crystalline structure	365:389	the crystalline structure of cellulose	365:402	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	0	29	theme	structure	46:54	arg1	modification					14:25	Non-enzymatic modification	0:25	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.	0:103	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	4	30	theme	concurrent	821:830	arg1	pathway					812:818	a non-enzymatic pathway	796:818	a non-enzymatic pathway	796:818	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	0	31	theme	crystalline	34:44	arg1	structure					46:54	crystalline structure	34:54	crystalline structure	34:54	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	5	32	theme	potential	1088:1096	arg1	application					1098:1108	its potential application	1084:1108	the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries	1019:1157	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	4	33	with	concurrent	821:830	arg1	changes					849:855	early-stage changes	837:855	early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	837:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	34	theme	crystalline	739:749	arg1	cellulose					751:759	crystalline cellulose	739:759	crystalline cellulose	739:759	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	0	35	theme	chemistry	60:68	arg1	modification					14:25	Non-enzymatic modification	0:25	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.	0:103	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	4	36	dep	wall	982:985	arg1	out					966:968	out	966:968	out	966:968	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	0	37	dep	structure	46:54	arg1	the					30:32	the	30:32	the	30:32	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	2	38	from	changes	354:360	arg1	decay					450:454	brown-rot decay	440:454	brown-rot decay	440:454	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	2	38	from	changes	354:360	arg1	structure					381:389	the crystalline structure	365:389	the crystalline structure of cellulose	365:402	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	3	39	theme	Fungal	457:462	arg1	action					464:469	Fungal action	457:469	Fungal action	457:469	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	5	40	theme	brown-rot	1057:1065	arg1	decay					1067:1071	brown-rot decay	1057:1071	brown-rot decay	1057:1071	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	4	41	theme	non-enzymatic	798:810	arg1	pathway					812:818	a non-enzymatic pathway	796:818	a non-enzymatic pathway	796:818	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	4	42	theme	depolymerized	919:931	arg1	polysaccharides					950:964	depolymerized less-crystalline polysaccharides	919:964	depolymerized less-crystalline polysaccharides	919:964	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	3	43	theme	crystallite	660:670	arg1	size					672:675	crystallite size	660:675	crystallite size	660:675	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	3	44	theme	celluloses	604:613	arg1	removal					574:580	early removal	568:580	early removal of the more amorphous celluloses	568:613	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	5	45	theme	non-enzymatic	1033:1045	arg1	system					1047:1052	a non-enzymatic system	1031:1052	a non-enzymatic system	1031:1052	Our work provides insight into the role of a non-enzymatic system in brown-rot decay as well as its potential application in lignocellulose preservation and biorefineries.					
35337493	1	46	theme	rapid	127:131	arg1	degradation					133:143	rapid degradation	127:143	rapid degradation by brown-rot fungi	127:162	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	3	47	theme	crystallite	539:549	arg1	width					551:555	crystallite width	539:555	crystallite width	539:555	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	1	48	theme	Masson	213:218	arg1	wall					230:233	Masson pine cell wall	213:233	Masson pine cell wall	213:233	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	4	49	theme	less-crystalline	933:948	arg1	polysaccharides					950:964	depolymerized less-crystalline polysaccharides	919:964	depolymerized less-crystalline polysaccharides	919:964	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	1	50	theme	pine	220:223	arg1	wall					230:233	Masson pine cell wall	213:233	Masson pine cell wall	213:233	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	0	51	theme	Masson	73:78	arg1	pine					80:83	Masson pine	73:83	Masson pine	73:83	Non-enzymatic modification of the crystalline structure and chemistry of Masson pine in brown-rot decay.					
35337493	4	52	theme	early-stage	837:847	arg1	changes					849:855	early-stage changes	837:855	early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall	837:985	All data suggest that hemicellulose, amorphous cellulose and crystalline cellulose are sequentially depolymerized via a non-enzymatic pathway, concurrent with early-stage changes in the rearrangement of cellulose chains and the diffusion of depolymerized less-crystalline polysaccharides out of the cell wall.					
35337493	1	53	theme	cell	225:228	arg1	wall					230:233	Masson pine cell wall	213:233	Masson pine cell wall	213:233	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	2	54	theme	brown-rot	440:448	arg1	decay					450:454	brown-rot decay	440:454	brown-rot decay	440:454	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	2	55	from	composition	417:427	arg1	decay					450:454	brown-rot decay	440:454	brown-rot decay	440:454	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	2	55	from	composition	417:427	arg1	structure					381:389	the crystalline structure	365:389	the crystalline structure of cellulose	365:402	In this study, Masson pine samples were incubated with Gloeophyllum trabeum to aid in characterizing changes in the crystalline structure of cellulose and chemical composition of wood in brown-rot decay.					
35337493	3	56	theme	amorphous	594:602	arg1	celluloses					604:613	the more amorphous celluloses	585:613	the more amorphous celluloses	585:613	Fungal action resulted in an initial increase in wood cellulose crystallinity and crystallite width because of early removal of the more amorphous celluloses, followed by a decrease in crystallinity and crystallite size.					
35337493	1	57	theme	brown-rot	148:156	arg1	fungi					158:162	brown-rot fungi	148:162	brown-rot fungi	148:162	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
35337493	1	58	theme	wall	230:233	arg1	microstructure					195:208	the microstructure	191:208	the microstructure of Masson pine cell wall	191:233	Masson pine undergoes rapid degradation by brown-rot fungi, but how the fungus alters the microstructure of Masson pine cell wall is still unclear.					
37258144	0	0	theme	Gut	102:104	arg1	Changes					117:123	Gut Microbiota Changes	102:123	Gut Microbiota Changes	102:123	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	1	1	contain	has	144:146	arg2	impact					162:167	a significant impact	148:167	a significant impact	148:167	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	1	1	contain	has	144:146	arg1	stress					137:142	Early life stress	126:142	Early life stress	126:142	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	4	2	theme	anxiety-like	844:855	arg1	time					886:889	decreased time	876:889	decreased time in the open arms in the elevated plus maze test	876:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	4	2	theme	anxiety-like	844:855	arg1	behaviors					857:865	anxiety-like behaviors	844:865	anxiety-like behaviors	844:865	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	7	3	theme	17-d	1340:1343	arg1	mice					1345:1348	2'-FL diet-fed 17-d mice	1325:1348	2'-FL diet-fed 17-d mice	1325:1348	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	6	4	theme	2'-FL	1222:1226	arg1	ingestion					1209:1217	post-weaning ingestion	1196:1217	post-weaning ingestion of 2'-FL	1196:1226	The behavioral and neural abnormalities caused by early weaning were alleviated by post-weaning ingestion of 2'-FL.					
37258144	6	5	theme	early	1163:1167	arg1	weaning					1169:1175	early weaning	1163:1175	early weaning	1163:1175	The behavioral and neural abnormalities caused by early weaning were alleviated by post-weaning ingestion of 2'-FL.					
37258144	1	6	theme	transient	246:254	arg1	consequences					256:267	lasting rather than transient consequences	226:267	lasting rather than transient consequences	226:267	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	8	7	theme	milk	1386:1389	arg1	oligosaccharides					1391:1406	human milk oligosaccharides	1380:1406	human milk oligosaccharides	1380:1406	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	7	8	theme	diet-fed	1292:1299	arg1	mice					1315:1318	control diet-fed 24-d and 17-d mice	1284:1318	control diet-fed 24-d and 17-d mice	1284:1318	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	3	9	theme	early	782:786	arg1	stress					793:798	early life stress	782:798	early life stress	782:798	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	0	10	theme	Microbiota	106:115	arg1	Changes					117:123	Gut Microbiota Changes	102:123	Gut Microbiota Changes	102:123	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	3	11	theme	2'-fucosyllactose	703:719	arg1	effects					692:698	the effects	688:698	the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress	688:798	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	4	12	theme	17-d	826:829	arg1	old					821:823	old	821:823	old	821:823	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	4	12	theme	17-d	826:829	arg1	mice					831:834	17-d mice	826:834	17-d mice	826:834	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	3	13	theme	life	788:791	arg1	stress					793:798	early life stress	782:798	early life stress	782:798	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	4	14	theme	open	898:901	arg1	arms					903:906	the open arms	894:906	the open arms in the elevated plus maze test	894:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	2	15	theme	recent	328:333	arg1	years					335:339	recent years	328:339	recent years	328:339	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	7	16	theme	17-d	1310:1313	arg1	mice					1315:1318	control diet-fed 24-d and 17-d mice	1284:1318	control diet-fed 24-d and 17-d mice	1284:1318	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	4	17	from	time	886:889	arg1	arms					903:906	the open arms	894:906	the open arms in the elevated plus maze test	894:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	7	18	theme	2'-FL	1325:1329	arg1	mice					1345:1348	2'-FL diet-fed 17-d mice	1325:1348	2'-FL diet-fed 17-d mice	1325:1348	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	6	19	theme	neural	1132:1137	arg1	abnormalities					1139:1151	The behavioral and neural abnormalities	1113:1151	The behavioral and neural abnormalities caused by early weaning	1113:1175	The behavioral and neural abnormalities caused by early weaning were alleviated by post-weaning ingestion of 2'-FL.					
37258144	7	20	theme	diet-fed	1331:1338	arg1	mice					1345:1348	2'-FL diet-fed 17-d mice	1325:1348	2'-FL diet-fed 17-d mice	1325:1348	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	5	21	theme	activity	1045:1052	arg1	c-Fos					1061:1065	the neuronal activity marker c-Fos	1032:1065	the neuronal activity marker c-Fos in the amygdala	1032:1081	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	3	22	from	effects	692:698	arg1	anxiety					763:769	anxiety	763:769	anxiety induced by early life stress	763:798	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	5	23	theme	cells	1003:1007	arg1	higher					1092:1097	higher	1092:1097	higher	1092:1097	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	5	23	theme	cells	1003:1007	arg1	number					993:998	The number	989:998	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala	989:1081	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	5	24	from	c-Fos	1061:1065	arg1	amygdala					1074:1081	the amygdala	1070:1081	the amygdala	1070:1081	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	7	25	theme	24-d	1301:1304	arg1	mice					1315:1318	control diet-fed 24-d and 17-d mice	1284:1318	control diet-fed 24-d and 17-d mice	1284:1318	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	5	26	theme	marker	1054:1059	arg1	c-Fos					1061:1065	the neuronal activity marker c-Fos	1032:1065	the neuronal activity marker c-Fos in the amygdala	1032:1081	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	1	27	theme	central	191:197	arg1	CNS					215:217	CNS	215:217	CNS	215:217	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	1	27	theme	central	191:197	arg1	system					207:212	the central nervous system	187:212	the central nervous system (CNS)	187:218	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	6	28	theme	behavioral	1117:1126	arg1	abnormalities					1139:1151	The behavioral and neural abnormalities	1113:1151	The behavioral and neural abnormalities caused by early weaning	1113:1175	The behavioral and neural abnormalities caused by early weaning were alleviated by post-weaning ingestion of 2'-FL.					
37258144	1	29	theme	nervous	199:205	arg1	CNS					215:217	CNS	215:217	CNS	215:217	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	1	29	theme	nervous	199:205	arg1	system					207:212	the central nervous system	187:212	the central nervous system (CNS)	187:218	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	0	30	theme	Weaning-Induced	35:49	arg1	Behavior					64:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	8	31	theme	anxiety	1445:1451	arg1	changes					1497:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	7	32	theme	control	1284:1290	arg1	mice					1315:1318	control diet-fed 24-d and 17-d mice	1284:1318	control diet-fed 24-d and 17-d mice	1284:1318	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	1	33	theme	system	207:212	arg1	development					172:182	development	172:182	development of the central nervous system (CNS)	172:218	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	2	34	theme	so-called	414:422	arg1	axis					445:448	the so-called brain-gut-microbiota axis	410:448	the so-called brain-gut-microbiota axis	410:448	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	8	35	theme	hyperactivity	1463:1475	arg1	changes					1497:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	2	36	theme	CNS	535:537	arg1	development					516:526	development	516:526	development of the CNS through the gut microbiota	516:564	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	1	37	theme	Early	126:130	arg1	stress					137:142	Early life stress	126:142	Early life stress	126:142	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	4	38	theme	maze	929:932	arg1	test					934:937	the elevated plus maze test	911:937	the elevated plus maze test	911:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	8	39	theme	amygdala	1454:1461	arg1	hyperactivity					1463:1475	amygdala hyperactivity	1454:1475	amygdala hyperactivity	1454:1475	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	4	40	theme	decreased	876:884	arg1	time					886:889	decreased time	876:889	decreased time in the open arms in the elevated plus maze test	876:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	3	41	theme	fecal	630:634	arg1	analyses					647:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	8	42	theme	microbiota	1486:1495	arg1	changes					1497:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	0	43	theme	Anxiety-Like	51:62	arg1	Behavior					64:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	3	44	theme	neurohistological	607:623	arg1	analyses					647:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	2	45	theme	brain-gut-microbiota	424:443	arg1	axis					445:448	the so-called brain-gut-microbiota axis	410:448	the so-called brain-gut-microbiota axis	410:448	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	2	46	theme	gut	387:389	arg1	microbiota					391:400	gut microbiota	387:400	gut microbiota	387:400	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	0	47	theme	Amygdala	74:81	arg1	Hyperactivity					83:95	Amygdala Hyperactivity	74:95	Amygdala Hyperactivity	74:95	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	5	48	theme	neuronal	1036:1043	arg1	c-Fos					1061:1065	the neuronal activity marker c-Fos	1032:1065	the neuronal activity marker c-Fos in the amygdala	1032:1081	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	6	49	theme	post-weaning	1196:1207	arg1	ingestion					1209:1217	post-weaning ingestion	1196:1217	post-weaning ingestion of 2'-FL	1196:1226	The behavioral and neural abnormalities caused by early weaning were alleviated by post-weaning ingestion of 2'-FL.					
37258144	7	50	theme	fecal	1252:1256	arg1	microbiota					1258:1267	the fecal microbiota	1248:1267	the fecal microbiota	1248:1267	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	8	51	theme	stress-induced	1430:1443	arg1	changes					1497:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	1	52	theme	life	132:135	arg1	stress					137:142	Early life stress	126:142	Early life stress	126:142	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	3	53	theme	human	732:736	arg1	2'-fucosyllactose					703:719	2'-fucosyllactose	703:719	2'-fucosyllactose (2'-FL)	703:727	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	3	53	theme	human	732:736	arg1	oligosaccharide					743:757	a human milk oligosaccharide	730:757	a human milk oligosaccharide	730:757	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	8	54	theme	human	1380:1384	arg1	oligosaccharides					1391:1406	human milk oligosaccharides	1380:1406	human milk oligosaccharides	1380:1406	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	7	55	theme	microbiota	1258:1267	arg1	composition					1233:1243	The composition	1229:1243	The composition of the fecal microbiota	1229:1267	The composition of the fecal microbiota differed among control diet-fed 24-d and 17-d mice, and 2'-FL diet-fed 17-d mice.					
37258144	8	56	theme	gut	1482:1484	arg1	microbiota					1486:1495	gut microbiota	1482:1495	gut microbiota	1482:1495	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	2	57	dep	CNS	379:381	arg1	the					375:377	the	375:377	the	375:377	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	2	58	theme	gut	551:553	arg1	microbiota					555:564	the gut microbiota	547:564	the gut microbiota	547:564	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	3	59	theme	early-weaned	659:670	arg1	mice					672:675	early-weaned mice	659:675	early-weaned mice	659:675	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	3	60	theme	behavioral	595:604	arg1	analyses					647:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	4	61	theme	24-d	977:980	arg1	old					972:974	old	972:974	old	972:974	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	4	61	theme	24-d	977:980	arg1	mice					982:985	24-d mice	977:985	24-d mice	977:985	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	5	62	theme	17-d	1102:1105	arg1	mice					1107:1110	17-d mice	1102:1110	17-d mice	1102:1110	The number of cells that were positive for the neuronal activity marker c-Fos in the amygdala was also higher in 17-d mice.					
37258144	3	63	theme	milk	738:741	arg1	2'-fucosyllactose					703:719	2'-fucosyllactose	703:719	2'-fucosyllactose (2'-FL)	703:727	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	3	63	theme	milk	738:741	arg1	oligosaccharide					743:757	a human milk oligosaccharide	730:757	a human milk oligosaccharide	730:757	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	3	64	theme	microbiota	636:645	arg1	analyses					647:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	behavioral, neurohistological, and fecal microbiota analyses	595:654	In this study, we performed behavioral, neurohistological, and fecal microbiota analyses in early-weaned mice to examine the effects of 2'-fucosyllactose (2'-FL), a human milk oligosaccharide, on anxiety induced by early life stress.					
37258144	8	65	theme	early	1424:1428	arg1	changes					1497:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes	1424:1503	These findings indicate that human milk oligosaccharides 2'-FL alleviate early stress-induced anxiety, amygdala hyperactivity, and gut microbiota changes.					
37258144	1	66	theme	significant	150:160	arg1	impact					162:167	a significant impact	148:167	a significant impact	148:167	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	1	67	theme	lasting	226:232	arg1	consequences					256:267	lasting rather than transient consequences	226:267	lasting rather than transient consequences	226:267	Early life stress has a significant impact on development of the central nervous system (CNS), with lasting rather than transient consequences; therefore, it is important to alleviate these effects.					
37258144	4	68	theme	elevated	915:922	arg1	test					934:937	the elevated plus maze test	911:937	the elevated plus maze test	911:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
37258144	0	69	theme	Early	29:33	arg1	Behavior					64:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	Early Weaning-Induced Anxiety-Like Behavior	29:71	2'-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes.					
37258144	2	70	theme	functional	342:351	arg1	communication					353:365	functional communication	342:365	functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis	342:448	In recent years, functional communication between the CNS and gut microbiota through the so-called brain-gut-microbiota axis has been examined, and it is likely that prebiotics contribute to development of the CNS through the gut microbiota.					
37258144	4	71	from	arms	903:906	arg1	test					934:937	the elevated plus maze test	911:937	the elevated plus maze test	911:937	Mice weaned at 17 d old (17-d mice) showed anxiety-like behaviors, such as decreased time in the open arms in the elevated plus maze test, compared to mice weaned at 24 d old (24-d mice).					
36425215	9	0	theme	95	1514:1515	arg1	%					1516:1516	%	1516:1516	%	1516:1516	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	4	1	theme	Fiber	576:580	arg1	intakes					590:596	Fiber and NSP intakes	576:596	Fiber and NSP intakes at baseline	576:608	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	10	2	theme	reduced	1686:1692	arg1	risk					1694:1697	a reduced risk	1684:1697	a reduced risk of colon cancer in Chinese Singaporeans	1684:1737	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	2	3	theme	risk	338:341	arg1	factor					343:348	a modifiable risk factor	325:348	a modifiable risk factor	325:348	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	4	4	theme	NSP	586:588	arg1	intakes					590:596	Fiber and NSP intakes	576:596	Fiber and NSP intakes at baseline	576:608	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	10	5	theme	Chinese	1718:1724	arg1	Singaporeans					1726:1737	Chinese Singaporeans	1718:1737	Chinese Singaporeans	1718:1737	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	7	6	theme	CRC	1097:1099	arg1	risk					1089:1092	the risk	1085:1092	the risk of CRC in a dose-dependent manner	1085:1126	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	3	7	theme	NSP	550:552	arg1	intakes					554:560	dietary fiber and NSP intakes	532:560	dietary fiber and NSP intakes	532:560	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	4	8	theme	food	660:663	arg1	questionnaire					675:687	a validated semi-quantitative food frequency questionnaire	630:687	a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database	630:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	10	9	theme	cancer	1708:1713	arg1	risk					1694:1697	a reduced risk	1684:1697	a reduced risk of colon cancer in Chinese Singaporeans	1684:1737	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	3	10	theme	fiber	540:544	arg1	intakes					554:560	dietary fiber and NSP intakes	532:560	dietary fiber and NSP intakes	532:560	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	9	11	dep	HRQ4	1496:1499	arg1	CI					1518:1519	95% CI	1514:1519	95% CI	1514:1519	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	11	dep	HRQ4	1496:1499	arg1	P					1533:1533	P =0.003	1533:1540	P =0.003	1533:1540	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	5	12	theme	95	844:845	arg1	%					846:846	%	846:846	%	846:846	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	9	13	theme	rectal	1548:1553	arg1	cancer					1555:1560	rectal cancer	1548:1560	rectal cancer	1548:1560	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	4	14	theme	validated	632:640	arg1	questionnaire					675:687	a validated semi-quantitative food frequency questionnaire	630:687	a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database	630:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	11	15	theme	Non-starch	1753:1762	arg1	polysaccharides					1764:1778	Significance Non-starch polysaccharides	1740:1778	Significance Non-starch polysaccharides	1740:1778	Significance Non-starch polysaccharides may be beneficial for colorectal cancer primary prevention.					
36425215	5	16	theme	confidence	848:857	arg1	CIs					870:872	CIs	870:872	CIs	870:872	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	5	16	theme	confidence	848:857	arg1	intervals					859:867	respective 95% confidence intervals	833:867	respective 95% confidence intervals (CIs)	833:873	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	4	17	theme	Composition	721:731	arg1	Database					733:740	the Singapore Food Composition Database	702:740	the Singapore Food Composition Database	702:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	5	18	theme	NSP	917:919	arg1	intakes					921:927	dietary fiber and NSP intakes	899:927	intakes	921:927	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	6	19	theme	follow-up	1006:1014	arg1	years					997:1001	17.5 years	992:1001	17.5 years of follow-up	992:1014	After an average of 17.5 years of follow-up, 2,140 participants developed CRC.					
36425215	4	20	from	baseline	601:608	arg1	intakes					590:596	Fiber and NSP intakes	576:596	Fiber and NSP intakes at baseline	576:608	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	1	21	theme	non-starch	138:147	arg1	polysaccharides					149:163	non-starch polysaccharides	138:163	non-starch polysaccharides	138:163	Dietary fiber or non-starch polysaccharides (NSP) may provide protection from CRC development.					
36425215	6	22	theme	years	997:1001	arg1	average					981:987	an average	978:987	an average of 17.5 years of follow-up	978:1014	After an average of 17.5 years of follow-up, 2,140 participants developed CRC.					
36425215	9	23	theme	95	1582:1583	arg1	%					1584:1584	%	1584:1584	%	1584:1584	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	7	24	from	manner	1121:1126	arg1	risk					1089:1092	the risk	1085:1092	the risk of CRC in a dose-dependent manner	1085:1126	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	4	25	theme	Singapore	706:714	arg1	Database					733:740	the Singapore Food Composition Database	702:740	the Singapore Food Composition Database	702:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	5	26	theme	proportional	747:758	arg1	model					778:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	11	27	theme	primary	1820:1826	arg1	prevention					1828:1837	colorectal cancer primary prevention	1802:1837	colorectal cancer primary prevention	1802:1837	Significance Non-starch polysaccharides may be beneficial for colorectal cancer primary prevention.					
36425215	0	28	theme	Colorectal	52:61	arg1	Cancer					63:68	Colorectal Cancer	52:68	Colorectal Cancer	52:68	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	8	29	theme	dietary	1294:1300	arg1	intake					1306:1311	dietary NSP intake	1294:1311	dietary NSP intake	1294:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	5	30	theme	regression	767:776	arg1	model					778:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	5	31	used	used	788:791	arg2	model					778:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	9	32	theme	inverse	1440:1446	arg1	association					1448:1458	This inverse association	1435:1458	This inverse association	1435:1458	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	3	33	theme	Chinese	371:377	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	33	theme	Chinese	371:377	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	8	34	theme	intake	1306:1311	arg1	quartiles					1270:1278	quartiles 2, 3 and 4 of dietary NSP intake	1270:1311	quartiles 2, 3 and 4 of dietary NSP intake	1270:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	3	35	theme	prospective	412:422	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	35	theme	prospective	412:422	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	0	36	theme	Dietary	0:6	arg1	Intake					33:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	0	37	theme	Polysaccharide	18:31	arg1	Intake					33:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	7	38	from	risk	1089:1092	arg1	manner					1121:1126	a dose-dependent manner	1104:1126	a dose-dependent manner	1104:1126	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	3	39	theme	cancer-free	441:451	arg1	Singaporeans					482:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	7	40	theme	dietary	1136:1142	arg1	fiber					1144:1148	dietary fiber	1136:1148	dietary fiber	1136:1148	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	9	41	theme	colon	1482:1486	arg1	cancer					1488:1493	colon cancer	1482:1493	colon cancer	1482:1493	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	6	42	theme	2,140	1017:1021	arg1	participants					1023:1034	2,140 participants	1017:1034	2,140 participants	1017:1034	After an average of 17.5 years of follow-up, 2,140 participants developed CRC.					
36425215	7	43	from	CRC	1097:1099	arg1	manner					1121:1126	a dose-dependent manner	1104:1126	a dose-dependent manner	1104:1126	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	7	44	theme	subtypes	1208:1215	arg1	risk					1174:1177	risk	1174:1177	risk of CRC overall or histologic subtypes	1174:1215	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	2	45	theme	modifiable	327:336	arg1	factor					343:348	a modifiable risk factor	325:348	a modifiable risk factor	325:348	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	3	46	theme	Chinese	474:480	arg1	Singaporeans					482:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	11	47	theme	colorectal	1802:1811	arg1	prevention					1828:1837	colorectal cancer primary prevention	1802:1837	colorectal cancer primary prevention	1802:1837	Significance Non-starch polysaccharides may be beneficial for colorectal cancer primary prevention.					
36425215	3	48	theme	middle-aged	453:463	arg1	Singaporeans					482:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	5	49	theme	hazard	809:814	arg1	HRs					824:826	HRs	824:826	HRs	824:826	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	5	49	theme	hazard	809:814	arg1	ratios					816:821	the hazard ratios	805:821	the hazard ratios (HRs)	805:827	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	0	50	from	Study	114:118	arg1	Findings					71:78	Findings	71:78	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.	0:119	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	9	51	theme	%	1516:1516	arg1	CI					1518:1519	95% CI	1514:1519	95% CI	1514:1519	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	51	theme	%	1516:1516	arg1	P					1533:1533	P =0.003	1533:1540	P =0.003	1533:1540	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	10	52	theme	dietary	1639:1645	arg1	NSP					1647:1649	dietary NSP	1639:1649	dietary NSP but not fiber	1639:1663	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	11	53	theme	cancer	1813:1818	arg1	prevention					1828:1837	colorectal cancer primary prevention	1802:1837	colorectal cancer primary prevention	1802:1837	Significance Non-starch polysaccharides may be beneficial for colorectal cancer primary prevention.					
36425215	3	54	theme	dietary	532:538	arg1	intakes					554:560	dietary fiber and NSP intakes	532:560	dietary fiber and NSP intakes	532:560	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	4	55	theme	semi-quantitative	642:658	arg1	questionnaire					675:687	a validated semi-quantitative food frequency questionnaire	630:687	a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database	630:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	10	56	theme	colon	1702:1706	arg1	cancer					1708:1713	colon cancer	1702:1713	colon cancer	1702:1713	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	3	57	theme	CRC	566:568	arg1	risk					570:573	CRC risk	566:573	CRC risk	566:573	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	4	58	theme	frequency	665:673	arg1	questionnaire					675:687	a validated semi-quantitative food frequency questionnaire	630:687	a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database	630:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	5	59	theme	respective	833:842	arg1	CIs					870:872	CIs	870:872	CIs	870:872	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	5	59	theme	respective	833:842	arg1	intervals					859:867	respective 95% confidence intervals	833:867	respective 95% confidence intervals (CIs)	833:873	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	10	60	from	risk	1694:1697	arg1	Singaporeans					1726:1737	Chinese Singaporeans	1718:1737	Chinese Singaporeans	1718:1737	Our findings suggested that dietary NSP but not fiber is associated with a reduced risk of colon cancer in Chinese Singaporeans.					
36425215	11	61	theme	Significance	1740:1751	arg1	polysaccharides					1764:1778	Significance Non-starch polysaccharides	1740:1778	Significance Non-starch polysaccharides	1740:1778	Significance Non-starch polysaccharides may be beneficial for colorectal cancer primary prevention.					
36425215	8	62	theme	multivariable-adjusted	1222:1243	arg1	0.99					1318:1321	0.99	1318:1321	0.99	1318:1321	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	62	theme	multivariable-adjusted	1222:1243	arg1	HRs					1245:1247	The multivariable-adjusted HRs	1218:1247	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake	1218:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	62	theme	multivariable-adjusted	1222:1243	arg1	CIs					1254:1256	95% CIs	1250:1256	95% CIs	1250:1256	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	5	63	theme	%	846:846	arg1	CIs					870:872	CIs	870:872	CIs	870:872	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	5	63	theme	%	846:846	arg1	intervals					859:867	respective 95% confidence intervals	833:867	respective 95% confidence intervals (CIs)	833:873	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	2	64	dep	studies	230:236	arg1	association					245:255	the association	241:255	the association between dietary fiber and CRC	241:285	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	2	64	dep	studies	230:236	arg1	inconsistent					290:301	inconsistent	290:301	inconsistent	290:301	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	5	65	theme	Cox	743:745	arg1	model					778:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	2	66	theme	Epidemiologic	216:228	arg1	studies					230:236	Epidemiologic studies	216:236	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent	216:301	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	1	67	from	development	203:213	arg1	protection					183:192	protection	183:192	protection from CRC development	183:213	Dietary fiber or non-starch polysaccharides (NSP) may provide protection from CRC development.					
36425215	5	68	theme	dietary	899:905	arg1	fiber					907:911	dietary fiber and NSP intakes	899:927	fiber	907:911	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	9	69	theme	HR	1563:1564	arg1	Q4					1566:1567	HR Q4	1563:1567	HR Q4	1563:1567	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	4	70	theme	Food	716:719	arg1	Database					733:740	the Singapore Food Composition Database	702:740	the Singapore Food Composition Database	702:740	Fiber and NSP intakes at baseline were obtained using a validated semi-quantitative food frequency questionnaire coupled with the Singapore Food Composition Database.					
36425215	9	71	dep	CI	1586:1587	arg1	0.74-1.13					1590:1598	0.74-1.13	1590:1598	0.74-1.13	1590:1598	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	2	72	theme	dietary	265:271	arg1	fiber					273:277	dietary fiber	265:277	dietary fiber	265:277	Epidemiologic studies on the association between dietary fiber and CRC is inconsistent are limited on NSP as a modifiable risk factor.					
36425215	1	73	theme	Dietary	121:127	arg1	NSP					166:168	NSP	166:168	NSP	166:168	Dietary fiber or non-starch polysaccharides (NSP) may provide protection from CRC development.					
36425215	1	73	theme	Dietary	121:127	arg1	fiber					129:133	Dietary fiber	121:133	Dietary fiber	121:133	Dietary fiber or non-starch polysaccharides (NSP) may provide protection from CRC development.					
36425215	8	74	theme	CRC	1262:1264	arg1	0.99					1318:1321	0.99	1318:1321	0.99	1318:1321	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	74	theme	CRC	1262:1264	arg1	HRs					1245:1247	The multivariable-adjusted HRs	1218:1247	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake	1218:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	74	theme	CRC	1262:1264	arg1	CIs					1254:1256	95% CIs	1250:1256	95% CIs	1250:1256	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	7	75	theme	histologic	1197:1206	arg1	subtypes					1208:1215	histologic subtypes	1197:1215	histologic subtypes	1197:1215	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	9	76	dep	apparent	1469:1476	arg1	Q4					1566:1567	HR Q4	1563:1567	HR Q4	1563:1567	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	76	dep	apparent	1469:1476	arg1	Q1=0.92					1573:1579	Q1=0.92	1573:1579	Q1=0.92	1573:1579	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	76	dep	apparent	1469:1476	arg1	Q1=0.79					1505:1511	Q1=0.79	1505:1511	Q1=0.79	1505:1511	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	76	dep	apparent	1469:1476	arg1	HRQ4					1496:1499	HRQ4	1496:1499	HRQ4	1496:1499	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	7	77	theme	CRC	1182:1184	arg1	risk					1174:1177	risk	1174:1177	risk of CRC overall or histologic subtypes	1174:1215	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	9	78	theme	%	1584:1584	arg1	P					1601:1601	P =0.53	1601:1607	P =0.53	1601:1607	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	78	theme	%	1584:1584	arg1	CI					1586:1587	95% CI	1582:1587	95% CI	1582:1587	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	8	79	theme	lowest	1407:1412	arg1	P					1424:1424	P =0.006	1424:1431	P =0.006	1424:1431	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	79	theme	lowest	1407:1412	arg1	quartile					1414:1421	the lowest quartile	1403:1421	the lowest quartile (P =0.006)	1403:1432	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	0	80	theme	Singapore	89:97	arg1	Study					114:118	the Singapore Chinese Health Study	85:118	the Singapore Chinese Health Study	85:118	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	5	81	theme	potential	949:957	arg1	confounders					959:969	potential confounders	949:969	potential confounders	949:969	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	0	82	theme	Health	107:112	arg1	Study					114:118	the Singapore Chinese Health Study	85:118	the Singapore Chinese Health Study	85:118	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	5	83	theme	hazard	760:765	arg1	model					778:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model	743:782	Cox proportional hazard regression model was used to estimate the hazard ratios (HRs) and respective 95% confidence intervals (CIs) for CRC associated with dietary fiber and NSP intakes after adjusting for potential confounders.					
36425215	0	84	theme	Nonstarch	8:16	arg1	Intake					33:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	3	85	theme	Health	379:384	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	85	theme	Health	379:384	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	8	86	theme	NSP	1302:1304	arg1	intake					1306:1311	dietary NSP intake	1294:1311	dietary NSP intake	1294:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	3	87	theme	Singapore	361:369	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	87	theme	Singapore	361:369	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	88	theme	older	468:472	arg1	Singaporeans					482:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	61,321 cancer-free middle-aged or older Chinese Singaporeans	434:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	1	89	theme	CRC	199:201	arg1	development					203:213	CRC development	199:213	CRC development	199:213	Dietary fiber or non-starch polysaccharides (NSP) may provide protection from CRC development.					
36425215	3	90	theme	population-based	395:410	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	90	theme	population-based	395:410	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	0	91	theme	Chinese	99:105	arg1	Study					114:118	the Singapore Chinese Health Study	85:118	the Singapore Chinese Health Study	85:118	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	7	92	theme	dose-dependent	1106:1119	arg1	manner					1121:1126	a dose-dependent manner	1104:1126	a dose-dependent manner	1104:1126	NSP was inversely associated with the risk of CRC in a dose-dependent manner whereas dietary fiber was not associated with risk of CRC overall or histologic subtypes.					
36425215	0	93	theme	Cancer	63:68	arg1	Risk					44:47	Risk	44:47	Risk	44:47	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	0	93	theme	Cancer	63:68	arg1	Intake					33:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake	0:38	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	0	94	dep	Intake	33:38	arg1	Findings					71:78	Findings	71:78	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.	0:119	Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study.					
36425215	3	95	theme	Singaporeans	482:493	arg1	cohort					424:429	a population-based prospective cohort	393:429	a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans	393:493	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	3	95	theme	Singaporeans	482:493	arg1	Study					386:390	the Singapore Chinese Health Study	357:390	the Singapore Chinese Health Study	357:390	Using the Singapore Chinese Health Study, a population-based prospective cohort of 61,321 cancer-free middle-aged or older Chinese Singaporeans, we examined the association between dietary fiber and NSP intakes and CRC risk.					
36425215	8	96	theme	%	1252:1252	arg1	HRs					1245:1247	The multivariable-adjusted HRs	1218:1247	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake	1218:1311	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	8	96	theme	%	1252:1252	arg1	CIs					1254:1256	95% CIs	1250:1256	95% CIs	1250:1256	The multivariable-adjusted HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of dietary NSP intake were 0.99 (0.88-1.11), 0.98 (0.87-1.11) and 0.84 (0.73-0.95), respectively, compared with the lowest quartile (P =0.006).					
36425215	9	97	dep	Q4	1566:1567	arg1	P					1601:1601	P =0.53	1601:1607	P =0.53	1601:1607	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	97	dep	Q4	1566:1567	arg1	CI					1586:1587	95% CI	1582:1587	95% CI	1582:1587	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
36425215	9	98	dep	CI	1518:1519	arg1	0.67-0.93					1522:1530	0.67-0.93	1522:1530	0.67-0.93	1522:1530	This inverse association was more apparent for colon cancer (HRQ4 vs. Q1=0.79, 95% CI: 0.67-0.93, P =0.003) than rectal cancer (HR Q4 vs. Q1=0.92, 95% CI: 0.74-1.13, P =0.53).					
35026542	4	0	theme	composite	540:548	arg1	scaffold					550:557	a new bone repair composite scaffold	522:557	a new bone repair composite scaffold (CS/OBC/nHAP)	522:571	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	4	0	theme	composite	540:548	arg1	CS/OBC/nHAP					560:570	CS/OBC/nHAP	560:570	CS/OBC/nHAP	560:570	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	5	1	theme	in-situ	685:691	arg1	crystallization					693:707	in-situ crystallization	685:707	in-situ crystallization of Ca2+/PO42- solution	685:730	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	8	2	theme	defect	1188:1193	arg1	model					1195:1199	The rat skull defect model	1174:1199	The rat skull defect model	1174:1199	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	5	3	theme	solution	723:730	arg1	crystallization					693:707	in-situ crystallization	685:707	in-situ crystallization of Ca2+/PO42- solution	685:730	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	9	4	theme	good	1363:1366	arg1	stability					1368:1376	good stability	1363:1376	good stability	1363:1376	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	6	5	theme	retention	968:976	arg1	performance					978:988	mechanical properties and water retention performance	936:988	mechanical properties and water retention performance	936:988	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	9	6	theme	CS/OBC/nHAP	1338:1348	arg1	scaffold					1350:1357	the CS/OBC/nHAP scaffold	1334:1357	the CS/OBC/nHAP scaffold	1334:1357	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	4	7	theme	low-cost	488:495	arg1	manufacturing					497:509	a low-cost manufacturing	486:509	a low-cost manufacturing	486:509	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	3	8	theme	repair	389:394	arg1	scaffolds					396:404	bone repair scaffolds	384:404	bone repair scaffolds	384:404	The first issues to be considered when constructing bone repair scaffolds include biocompatibility, stress resistance, degradability and stability.					
35026542	6	9	theme	water	962:966	arg1	retention					968:976	water retention	962:976	water retention	962:976	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	3	10	theme	stress	432:437	arg1	resistance					439:448	stress resistance	432:448	stress resistance	432:448	The first issues to be considered when constructing bone repair scaffolds include biocompatibility, stress resistance, degradability and stability.					
35026542	2	11	theme	osteoblasts	319:329	arg1	differentiation					300:314	differentiation	300:314	differentiation	300:314	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	2	11	theme	osteoblasts	319:329	arg1	proliferation					282:294	proliferation	282:294	proliferation	282:294	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	8	12	theme	CS/OBC/nHAP	1225:1235	arg1	scaffold					1237:1244	the CS/OBC/nHAP scaffold	1221:1244	the CS/OBC/nHAP scaffold	1221:1244	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	4	13	theme	new	524:526	arg1	scaffold					550:557	a new bone repair composite scaffold	522:557	a new bone repair composite scaffold (CS/OBC/nHAP)	522:571	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	4	13	theme	new	524:526	arg1	CS/OBC/nHAP					560:570	CS/OBC/nHAP	560:570	CS/OBC/nHAP	560:570	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	5	14	theme	Ca2+/PO42-	712:721	arg1	solution					723:730	Ca2+/PO42- solution	712:730	Ca2+/PO42- solution	712:730	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	8	15	theme	skull	1182:1186	arg1	model					1195:1199	The rat skull defect model	1174:1199	The rat skull defect model	1174:1199	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	7	16	contain	has	1085:1087	arg1	scaffold					1076:1083	the CS/OBC/nHAP scaffold	1060:1083	the CS/OBC/nHAP scaffold	1060:1083	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	7	16	contain	has	1085:1087	arg2	biocompatibility					1094:1109	good biocompatibility	1089:1109	good biocompatibility	1089:1109	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	6	17	theme	properties	947:956	arg1	performance					978:988	mechanical properties and water retention performance	936:988	mechanical properties and water retention performance	936:988	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	1	18	theme	Bone	81:84	arg1	engineering					93:103	Bone tissue engineering	81:103	Bone tissue engineering	81:103	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	1	19	theme	bone	170:173	arg1	defects					175:181	bone defects	170:181	bone defects	170:181	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	3	20	dep	issues	342:347	arg1	considered					355:364	considered	355:364	to be considered	349:364	The first issues to be considered when constructing bone repair scaffolds include biocompatibility, stress resistance, degradability and stability.					
35026542	4	21	theme	repair	533:538	arg1	scaffold					550:557	a new bone repair composite scaffold	522:557	a new bone repair composite scaffold (CS/OBC/nHAP)	522:571	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	4	21	theme	repair	533:538	arg1	CS/OBC/nHAP					560:570	CS/OBC/nHAP	560:570	CS/OBC/nHAP	560:570	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	5	22	theme	natural	610:616	arg1	components					626:635	only natural derived components	605:635	only natural derived components	605:635	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	22	theme	natural	610:616	arg1	hydroxyapatite					653:666	nano hydroxyapatite	648:666	nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	648:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	1	23	theme	tissue	86:91	arg1	engineering					93:103	Bone tissue engineering	81:103	Bone tissue engineering	81:103	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	1	24	theme	defects	175:181	arg1	regeneration					154:165	regeneration	154:165	regeneration	154:165	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	1	24	theme	defects	175:181	arg1	repair					143:148	repair	143:148	repair	143:148	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	0	25	theme	bacterial	9:17	arg1	cellulose					19:27	Oxidized bacterial cellulose	0:27	Oxidized bacterial cellulose	0:27	Oxidized bacterial cellulose reinforced nanocomposite scaffolds for bone repair.					
35026542	4	26	theme	bone	528:531	arg1	scaffold					550:557	a new bone repair composite scaffold	522:557	a new bone repair composite scaffold (CS/OBC/nHAP)	522:571	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	4	26	theme	bone	528:531	arg1	CS/OBC/nHAP					560:570	CS/OBC/nHAP	560:570	CS/OBC/nHAP	560:570	Here, a low-cost manufacturing introduces a new bone repair composite scaffold (CS/OBC/nHAP).					
35026542	7	27	theme	MC3T3-E1	1158:1165	arg1	cells					1167:1171	MC3T3-E1 cells	1158:1171	MC3T3-E1 cells	1158:1171	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	5	28	theme	derived	618:624	arg1	components					626:635	only natural derived components	605:635	only natural derived components	605:635	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	28	theme	derived	618:624	arg1	hydroxyapatite					653:666	nano hydroxyapatite	648:666	nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	648:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	9	29	contain	has	1359:1361	arg2	stability					1368:1376	good stability	1363:1376	good stability	1363:1376	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	9	29	contain	has	1359:1361	arg1	scaffold					1350:1357	the CS/OBC/nHAP scaffold	1334:1357	the CS/OBC/nHAP scaffold	1334:1357	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	2	30	dep	proliferation	282:294	arg1	the					278:280	the	278:280	the	278:280	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	0	31	theme	Oxidized	0:7	arg1	cellulose					19:27	Oxidized bacterial cellulose	0:27	Oxidized bacterial cellulose	0:27	Oxidized bacterial cellulose reinforced nanocomposite scaffolds for bone repair.					
35026542	7	32	theme	cells	1167:1171	arg1	proliferation					1141:1153	the proliferation	1137:1153	the proliferation of MC3T3-E1 cells	1137:1171	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	8	33	theme	bone	1276:1279	arg1	tissue					1281:1286	bone tissue	1276:1286	bone tissue	1276:1286	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	1	34	dep	repair	143:148	arg1	the					139:141	the	139:141	the	139:141	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	6	35	theme	degradation	1013:1023	arg1	rate					1025:1028	a more stable degradation rate	999:1028	a more stable degradation rate	999:1028	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	5	36	theme	oxidized	756:763	arg1	scaffolds					809:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	2	37	theme	Tissue-engineered	184:200	arg1	scaffolds					207:215	Tissue-engineered bone scaffolds	184:215	Tissue-engineered bone scaffolds	184:215	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	1	38	used	used	121:124	arg2	engineering					93:103	Bone tissue engineering	81:103	Bone tissue engineering	81:103	Bone tissue engineering has been widely used in promoting the repair and regeneration of bone defects.					
35026542	6	39	theme	stable	1006:1011	arg1	rate					1025:1028	a more stable degradation rate	999:1028	a more stable degradation rate	999:1028	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	5	40	theme	bacterial	765:773	arg1	OBC					786:788	OBC	786:788	OBC	786:788	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	40	theme	bacterial	765:773	arg1	cellulose					775:783	bacterial cellulose	765:783	bacterial cellulose (OBC)	765:789	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	0	41	theme	nanocomposite	40:52	arg1	scaffolds					54:62	nanocomposite scaffolds	40:62	nanocomposite scaffolds for bone repair	40:78	Oxidized bacterial cellulose reinforced nanocomposite scaffolds for bone repair.					
35026542	9	42	theme	bone	1428:1431	arg1	tissue					1433:1438	bone tissue	1428:1438	bone tissue	1428:1438	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	5	43	theme	cellulose	775:783	arg1	scaffolds					809:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	2	44	theme	matrix	248:253	arg1	environment					255:265	the extracellular matrix environment	230:265	the extracellular matrix environment	230:265	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	3	45	theme	bone	384:387	arg1	scaffolds					396:404	bone repair scaffolds	384:404	bone repair scaffolds	384:404	The first issues to be considered when constructing bone repair scaffolds include biocompatibility, stress resistance, degradability and stability.					
35026542	0	46	theme	bone	68:71	arg1	repair					73:78	bone repair	68:78	bone repair	68:78	Oxidized bacterial cellulose reinforced nanocomposite scaffolds for bone repair.					
35026542	9	47	theme	tissue	1433:1438	arg1	formation					1415:1423	the formation	1411:1423	the formation of bone tissue	1411:1438	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	3	48	theme	first	336:340	arg1	issues					342:347	The first issues	332:347	The first issues to be considered when constructing bone repair scaffolds	332:404	The first issues to be considered when constructing bone repair scaffolds include biocompatibility, stress resistance, degradability and stability.					
35026542	6	49	theme	CS/OBC/nHAP	889:899	arg1	scaffold					901:908	CS/OBC/nHAP scaffold	889:908	CS/OBC/nHAP scaffold	889:908	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	2	50	theme	extracellular	234:246	arg1	environment					255:265	the extracellular matrix environment	230:265	the extracellular matrix environment	230:265	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	6	51	theme	mechanical	936:945	arg1	properties					947:956	mechanical properties	936:956	mechanical properties	936:956	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	8	52	theme	rat	1178:1180	arg1	model					1195:1199	The rat skull defect model	1174:1199	The rat skull defect model	1174:1199	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	7	53	theme	CS/OBC/nHAP	1064:1074	arg1	scaffold					1076:1083	the CS/OBC/nHAP scaffold	1060:1083	the CS/OBC/nHAP scaffold	1060:1083	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	5	54	dep	hydroxyapatite	653:666	arg1	formed					675:680	formed	675:680	formed by in-situ crystallization of Ca2+/PO42- solution	675:730	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	54	dep	hydroxyapatite	653:666	arg1	dispersed					743:751	dispersed	743:751	evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	736:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	7	55	theme	good	1089:1092	arg1	biocompatibility					1094:1109	good biocompatibility	1089:1109	good biocompatibility	1089:1109	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	6	56	theme	experimental	824:835	arg1	results					837:843	The experimental results	820:843	The experimental results	820:843	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	5	57	theme	nano	648:651	arg1	nHAP					669:672	nHAP	669:672	nHAP	669:672	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	57	theme	nano	648:651	arg1	hydroxyapatite					653:666	nano hydroxyapatite	648:666	nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	648:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	58	theme	only	605:608	arg1	components					626:635	only natural derived components	605:635	only natural derived components	605:635	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	58	theme	only	605:608	arg1	hydroxyapatite					653:666	nano hydroxyapatite	648:666	nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	648:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	6	59	theme	CS/nHAP	871:877	arg1	scaffold					879:886	CS/nHAP scaffold	871:886	CS/nHAP scaffold	871:886	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	6	60	contain	has	995:997	arg1	scaffold					901:908	CS/OBC/nHAP scaffold	889:908	CS/OBC/nHAP scaffold	889:908	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	6	60	contain	has	995:997	arg2	rate					1025:1028	a more stable degradation rate	999:1028	a more stable degradation rate	999:1028	The experimental results showed that compared with CS/nHAP scaffold, CS/OBC/nHAP scaffold has significantly improve mechanical properties and water retention performance, and has a more stable degradation rate.					
35026542	8	61	theme	tissue	1281:1286	arg1	formation					1263:1271	the formation	1259:1271	the formation of bone tissue	1259:1286	The rat skull defect model further proves that the CS/OBC/nHAP scaffold could induce the formation of bone tissue.					
35026542	5	62	theme	chitosan	795:802	arg1	scaffolds					809:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	756:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	2	63	theme	bone	202:205	arg1	scaffolds					207:215	Tissue-engineered bone scaffolds	184:215	Tissue-engineered bone scaffolds	184:215	Tissue-engineered bone scaffolds can simulate the extracellular matrix environment and induce the proliferation and differentiation of osteoblasts.					
35026542	9	64	theme	H&E	1300:1302	arg1	Meanwhile					1289:1297	Meanwhile	1289:1297	Meanwhile	1289:1297	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	9	64	theme	H&E	1300:1302	arg1	staining					1304:1311	H&E staining	1300:1311	H&E staining experiment	1300:1322	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	9	65	dep	staining	1304:1311	arg1	experiment					1313:1322	experiment	1313:1322	H&E staining experiment	1300:1322	Meanwhile, H&E staining experiment show that the CS/OBC/nHAP scaffold has good stability in vivo and could better promote the formation of bone tissue.					
35026542	7	66	theme	Cell	1031:1034	arg1	experiments					1036:1046	Cell experiments	1031:1046	Cell experiments	1031:1046	Cell experiments showed that the CS/OBC/nHAP scaffold has good biocompatibility and significantly promote the proliferation of MC3T3-E1 cells.					
35026542	5	67	link	derived	618:624	arg1	components					626:635	only natural derived components	605:635	only natural derived components	605:635	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
35026542	5	67	link	derived	618:624	arg1	hydroxyapatite					653:666	nano hydroxyapatite	648:666	nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds	648:817	The scaffolds were composed of only natural derived components, including nano hydroxyapatite (nHAP) formed by in-situ crystallization of Ca2+/PO42- solution and evenly dispersed in oxidized bacterial cellulose (OBC) and chitosan (CS) scaffolds.					
36285360	6	0	theme	TADDS	1036:1040	arg1	concept					1053:1059	a TADDS shelf-life concept	1034:1059	a TADDS shelf-life concept	1034:1059	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	3	1	theme	drug-loaded	584:594	arg1	nano					596:599	drug-loaded nano	584:599	drug-loaded nano	584:599	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	4	2	theme	ultrasound	679:688	arg1	pulses					690:695	ultrasound pulses	679:695	ultrasound pulses	679:695	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	3	3	theme	stimuli-responsive	358:375	arg1	release					388:394	the stimuli-responsive controlled release	354:394	the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	354:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	4	from	systems	485:491	arg1	release					388:394	the stimuli-responsive controlled release	354:394	the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	354:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	4	5	with	Stimulation	662:672	arg1	pulses					690:695	ultrasound pulses	679:695	ultrasound pulses	679:695	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	4	5	with	Stimulation	662:672	arg1	changes					712:718	temperature changes	700:718	temperature changes	700:718	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	1	6	theme	extended	162:169	arg1	manner					171:176	an extended manner	159:176	an extended manner	159:176	Hydrogel-based drug delivery systems typically aim to release drugs locally to tissue in an extended manner.					
36285360	4	7	from	TADDS	795:799	arg1	release					751:757	the release	747:757	the release of triamcinolone acetonide from the TADDS	747:799	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	3	8	theme	acetonide	413:421	arg1	release					388:394	the stimuli-responsive controlled release	354:394	the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	354:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	9	dep	approaches	518:527	arg1	combine					532:538	combine	532:538	combine	532:538	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	2	10	theme	triamcinolone	323:335	arg1	acetonide					337:345	the corticosteroid triamcinolone acetonide	304:345	the corticosteroid triamcinolone acetonide	304:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	5	11	theme	PLGA	849:852	arg1	microparticles					854:867	PLGA microparticles	849:867	PLGA microparticles	849:867	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	2	12	theme	corticosteroid	308:321	arg1	acetonide					337:345	the corticosteroid triamcinolone acetonide	304:345	the corticosteroid triamcinolone acetonide	304:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	0	13	theme	Controlled	0:9	arg1	Delivery					11:18	Controlled Delivery	0:18	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.	0:68	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.					
36285360	5	14	theme	microparticles	854:867	arg1	incorporation					806:818	The incorporation	802:818	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel	802:891	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	6	15	theme	technical	1009:1017	arg1	exploration					1019:1029	A first technical exploration	1001:1029	A first technical exploration of a TADDS shelf-life concept	1001:1059	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	1	16	theme	drug	85:88	arg1	systems					99:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems typically aim to release drugs locally to tissue in an extended manner.					
36285360	5	17	theme	acetonide	990:998	arg1	release					965:971	the release	961:971	the release of triamcinolone acetonide	961:998	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	4	18	theme	triamcinolone	762:774	arg1	acetonide					776:784	triamcinolone acetonide	762:784	triamcinolone acetonide	762:784	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	3	19	theme	triamcinolone	399:411	arg1	acetonide					413:421	triamcinolone acetonide	399:421	triamcinolone acetonide	399:421	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	6	20	theme	first	1003:1007	arg1	exploration					1019:1029	A first technical exploration	1001:1029	A first technical exploration of a TADDS shelf-life concept	1001:1059	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	7	21	theme	technology	1285:1294	arg1	platform					1296:1303	a suggested technology platform	1273:1303	a suggested technology platform for controlled drug delivery	1273:1332	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	7	21	theme	technology	1285:1294	arg1	TADDS					1263:1267	the TADDS	1259:1267	the TADDS	1259:1267	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	1	22	theme	delivery	90:97	arg1	systems					99:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems typically aim to release drugs locally to tissue in an extended manner.					
36285360	3	23	theme	evolving	505:512	arg1	approaches					518:527	evolving new approaches	505:527	evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	505:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	24	theme	tough	456:460	arg1	TADDS					494:498	TADDS	494:498	TADDS	494:498	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	24	theme	tough	456:460	arg1	systems					485:491	the alginate-polyacrylamide tough hydrogel drug delivery systems	428:491	the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS)	428:499	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	5	25	theme	laponite	823:830	arg1	nanoparticles					832:844	laponite nanoparticles	823:844	laponite nanoparticles	823:844	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	3	26	theme	hydrogel	462:469	arg1	TADDS					494:498	TADDS	494:498	TADDS	494:498	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	26	theme	hydrogel	462:469	arg1	systems					485:491	the alginate-polyacrylamide tough hydrogel drug delivery systems	428:491	the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS)	428:499	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	6	27	theme	lyophilized	1102:1112	arg1	TADDS					1114:1118	lyophilized TADDS	1102:1118	lyophilized TADDS	1102:1118	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	0	28	theme	Tough	53:57	arg1	Adhesives					59:67	Tunable Tough Adhesives	45:67	Tunable Tough Adhesives	45:67	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.					
36285360	4	29	theme	acetonide	776:784	arg1	release					751:757	the release	747:757	the release of triamcinolone acetonide from the TADDS	747:799	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	0	30	theme	Corticosteroids	23:37	arg1	Delivery					11:18	Controlled Delivery	0:18	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.	0:68	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.					
36285360	6	31	theme	released	1173:1180	arg1	acetonide					1196:1204	released triamcinolone acetonide	1173:1204	released triamcinolone acetonide	1173:1204	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	6	32	theme	acetonide	1196:1204	arg1	integrity					1160:1168	the bioactive integrity	1146:1168	the bioactive integrity of released triamcinolone acetonide	1146:1204	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	3	33	theme	alginate-polyacrylamide	432:454	arg1	TADDS					494:498	TADDS	494:498	TADDS	494:498	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	33	theme	alginate-polyacrylamide	432:454	arg1	systems					485:491	the alginate-polyacrylamide tough hydrogel drug delivery systems	428:491	the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS)	428:499	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	2	34	theme	adhesive	186:193	arg1	hydrogels					225:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	34	theme	adhesive	186:193	arg1	system					293:298	an extended-release system	273:298	an extended-release system for the corticosteroid triamcinolone acetonide	273:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	6	35	theme	triamcinolone	1182:1194	arg1	acetonide					1196:1204	released triamcinolone acetonide	1173:1204	released triamcinolone acetonide	1173:1204	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	0	36	theme	Tunable	45:51	arg1	Adhesives					59:67	Tunable Tough Adhesives	45:67	Tunable Tough Adhesives	45:67	Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives.					
36285360	1	37	theme	Hydrogel-based	70:83	arg1	systems					99:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems	70:105	Hydrogel-based drug delivery systems typically aim to release drugs locally to tissue in an extended manner.					
36285360	2	38	theme	Tissue	179:184	arg1	hydrogels					225:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	38	theme	Tissue	179:184	arg1	system					293:298	an extended-release system	273:298	an extended-release system for the corticosteroid triamcinolone acetonide	273:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	3	39	theme	new	514:516	arg1	approaches					518:527	evolving new approaches	505:527	evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	505:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	5	40	theme	nanoparticles	832:844	arg1	incorporation					806:818	The incorporation	802:818	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel	802:891	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	3	41	theme	drug	471:474	arg1	TADDS					494:498	TADDS	494:498	TADDS	494:498	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	41	theme	drug	471:474	arg1	systems					485:491	the alginate-polyacrylamide tough hydrogel drug delivery systems	428:491	the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS)	428:499	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	42	from	approaches	518:527	arg1	release					388:394	the stimuli-responsive controlled release	354:394	the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	354:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	43	theme	delivery	476:483	arg1	TADDS					494:498	TADDS	494:498	TADDS	494:498	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	3	43	theme	delivery	476:483	arg1	systems					485:491	the alginate-polyacrylamide tough hydrogel drug delivery systems	428:491	the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS)	428:499	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	6	44	theme	shelf-life	1042:1051	arg1	concept					1053:1059	a TADDS shelf-life concept	1034:1059	a TADDS shelf-life concept	1034:1059	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	7	45	theme	properties	1247:1256	arg1	tunability					1233:1242	the tunability	1229:1242	the tunability of properties	1229:1256	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	6	46	theme	concept	1053:1059	arg1	exploration					1019:1029	A first technical exploration	1001:1029	A first technical exploration of a TADDS shelf-life concept	1001:1059	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	7	47	theme	suggested	1275:1283	arg1	platform					1296:1303	a suggested technology platform	1273:1303	a suggested technology platform for controlled drug delivery	1273:1332	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	7	47	theme	suggested	1275:1283	arg1	TADDS					1263:1267	the TADDS	1259:1267	the TADDS	1259:1267	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	6	48	theme	bioactive	1150:1158	arg1	integrity					1160:1168	the bioactive integrity	1146:1168	the bioactive integrity of released triamcinolone acetonide	1146:1204	A first technical exploration of a TADDS shelf-life concept is performed using lyophilization, where lyophilized TADDS are physically stable and the bioactive integrity of released triamcinolone acetonide is demonstrated.					
36285360	3	49	theme	alginate-polyacrylamide	540:562	arg1	hydrogel					570:577	alginate-polyacrylamide tough hydrogel	540:577	alginate-polyacrylamide tough hydrogel	540:577	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	2	50	theme	tough	219:223	arg1	hydrogels					225:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	50	theme	tough	219:223	arg1	system					293:298	an extended-release system	273:298	an extended-release system for the corticosteroid triamcinolone acetonide	273:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	51	theme	extended-release	276:291	arg1	hydrogels					225:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	51	theme	extended-release	276:291	arg1	system					293:298	an extended-release system	273:298	an extended-release system for the corticosteroid triamcinolone acetonide	273:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	3	52	theme	tough	564:568	arg1	hydrogel					570:577	alginate-polyacrylamide tough hydrogel	540:577	alginate-polyacrylamide tough hydrogel	540:577	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	4	53	theme	temperature	700:710	arg1	changes					712:718	temperature changes	700:718	temperature changes	700:718	Stimulation with ultrasound pulses or temperature changes is demonstrated to control the release of triamcinolone acetonide from the TADDS.					
36285360	3	54	theme	controlled	377:386	arg1	release					388:394	the stimuli-responsive controlled release	354:394	the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS	354:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	2	55	theme	alginate-polyacrylamide	195:217	arg1	hydrogels					225:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels	179:233	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	2	55	theme	alginate-polyacrylamide	195:217	arg1	system					293:298	an extended-release system	273:298	an extended-release system for the corticosteroid triamcinolone acetonide	273:345	Tissue adhesive alginate-polyacrylamide tough hydrogels are recently demonstrated to serve as an extended-release system for the corticosteroid triamcinolone acetonide.					
36285360	5	56	theme	triamcinolone	976:988	arg1	acetonide					990:998	triamcinolone acetonide	976:998	triamcinolone acetonide	976:998	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	5	57	theme	tough	878:882	arg1	hydrogel					884:891	the tough hydrogel	874:891	the tough hydrogel	874:891	The incorporation of laponite nanoparticles or PLGA microparticles into the tough hydrogel is shown to further enhance the versatility to control and modulate the release of triamcinolone acetonide.					
36285360	3	58	theme	composite	632:640	arg1	TADDS					642:646	composite TADDS	632:646	composite TADDS	632:646	Here, the stimuli-responsive controlled release of triamcinolone acetonide from the alginate-polyacrylamide tough hydrogel drug delivery systems (TADDS) and evolving new approaches to combine alginate-polyacrylamide tough hydrogel with drug-loaded nano and microparticles, generating composite TADDS is described.					
36285360	7	59	theme	controlled	1309:1318	arg1	delivery					1325:1332	controlled drug delivery	1309:1332	controlled drug delivery	1309:1332	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36285360	7	60	theme	drug	1320:1323	arg1	delivery					1325:1332	controlled drug delivery	1309:1332	controlled drug delivery	1309:1332	Given the tunability of properties, the TADDS are a suggested technology platform for controlled drug delivery.					
36867618	8	0	theme	biocomposite	1176:1187	arg1	film					1189:1192	the biocomposite film	1172:1192	the biocomposite film	1172:1192	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	6	1	theme	PALF-MCC	940:947	arg1	laurate					949:955	esterified PALF-MCC laurate	929:955	esterified PALF-MCC laurate	929:955	The addition of esterified PALF-MCC laurate increased the degradation temperature.					
36867618	5	2	theme	thermal	671:677	arg1	properties					679:688	The thermal properties	667:688	The thermal properties obtained by differential scanning calorimetry	667:734	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	9	3	theme	laurate	1427:1433	arg1	ester					1435:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	4	4	theme	film	603:606	arg1	morphology					616:625	the film surface morphology	599:625	the film surface morphology	599:625	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	2	5	theme	pineapple	376:384	arg1	PALF-MCC					399:406	PALF-MCC	399:406	PALF-MCC	399:406	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	2	5	theme	pineapple	376:384	arg1	fibres					391:396	pineapple leaf fibres	376:396	pineapple leaf fibres (PALF-MCC)	376:407	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	3	6	with	compatibility	421:433	arg1	PHB					440:442	PHB	440:442	PHB	440:442	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	9	7	theme	PALF-MCC	1418:1425	arg1	ester					1435:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	9	8	contain	had	1441:1443	arg1	films					1395:1399	PHB/ esterified PALF-MCC laurate films	1362:1399	PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester	1362:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	9	8	contain	had	1441:1443	arg2	degradation					1452:1462	higher degradation	1445:1462	higher degradation	1445:1462	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	2	9	theme	degradable	275:284	arg1	biocomposites					292:304	fully degradable green biocomposites	269:304	fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC)	269:407	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	1	10	theme	26.9	209:212	arg1	%					213:213	%	213:213	%	213:213	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	8	11	theme	tensile	1227:1233	arg1	strength					1235:1242	tensile strength	1227:1242	tensile strength	1227:1242	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	7	12	from	break	1043:1047	arg1	elongation					1029:1038	elongation	1029:1038	elongation	1029:1038	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	7	12	from	break	1043:1047	arg1	strength					1016:1023	maximum tensile strength	1000:1023	maximum tensile strength	1000:1023	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	10	13	theme	agricultural	1594:1605	arg1	wastes					1607:1612	pineapple agricultural wastes	1584:1612	pineapple agricultural wastes	1584:1612	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	5	14	theme	wt	856:857	arg1	%					858:858	100 wt%	852:858	100 wt%	852:858	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	8	15	from	increase	1281:1288	arg1	elongation					1293:1302	elongation	1293:1302	elongation	1293:1302	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	9	16	theme	%	1492:1492	arg1	PHB					1494:1496	100% PHB	1489:1496	100% PHB	1489:1496	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	8	17	theme	modulus	1256:1262	arg1	value					1218:1222	a pleasant value	1207:1222	a pleasant value of tensile strength and elastic modulus	1207:1262	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	6	18	theme	degradation	971:981	arg1	temperature					983:993	the degradation temperature	967:993	the degradation temperature	967:993	The addition of esterified PALF-MCC laurate increased the degradation temperature.					
36867618	5	19	theme	differential	702:713	arg1	calorimetry					724:734	differential scanning calorimetry	702:734	differential scanning calorimetry	702:734	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	1	20	theme	leaf	140:143	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	20	theme	leaf	140:143	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	0	21	from	leaf	124:127	arg1	cellulose					99:107	microcrystalline cellulose	82:107	microcrystalline cellulose from pineapple leaf	82:127	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	9	22	theme	%	1504:1504	arg1	laurate					1526:1532	100% esterified PALF-MCC laurate	1501:1532	100% esterified PALF-MCC laurate	1501:1532	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	9	23	theme	PALF-MCC	1517:1524	arg1	laurate					1526:1532	100% esterified PALF-MCC laurate	1501:1532	100% esterified PALF-MCC laurate	1501:1532	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	5	24	dep	revealed	736:743	arg1	whereas					844:850	whereas	844:850	whereas	844:850	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	0	25	theme	microcrystalline	82:97	arg1	cellulose					99:107	microcrystalline cellulose	82:107	microcrystalline cellulose from pineapple leaf	82:127	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	7	26	theme	maximum	1000:1006	arg1	strength					1016:1023	maximum tensile strength	1000:1023	maximum tensile strength	1000:1023	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	1	27	theme	waste	181:185	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	27	theme	waste	181:185	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	10	28	theme	biocomposite	1682:1693	arg1	compostable					1715:1725	100% compostable	1710:1725	100% compostable in soil	1710:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	10	28	theme	biocomposite	1682:1693	arg1	films					1695:1699	relatively low-cost biocomposite films	1662:1699	relatively low-cost biocomposite films that are 100% compostable in soil	1662:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	4	29	from	changes	588:594	arg1	morphology					616:625	the film surface morphology	599:625	the film surface morphology	599:625	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	9	30	theme	burial	1346:1351	arg1	testing					1353:1359	soil burial testing	1341:1359	soil burial testing	1341:1359	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	0	31	theme	Green	0:4	arg1	composites					6:15	Green composites	0:15	Green composites made of polyhydroxybutyrate and long-chain fatty acid	0:69	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	4	32	theme	PALF-MCC	559:566	arg1	content					576:582	the esterified PALF-MCC laurate content	544:582	the esterified PALF-MCC laurate content	544:582	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	10	33	theme	100	1710:1712	arg1	%					1713:1713	%	1713:1713	%	1713:1713	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	9	34	theme	esterified	1367:1376	arg1	films					1395:1399	PHB/ esterified PALF-MCC laurate films	1362:1399	PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester	1362:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	4	35	theme	content	576:582	arg1	influence					531:539	The influence	527:539	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties	527:652	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	1	36	contain	contains	200:207	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	36	contain	contains	200:207	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	36	contain	contains	200:207	arg2	cellulose					215:223	26.9% cellulose	209:223	26.9% cellulose	209:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	9	37	theme	higher	1445:1450	arg1	degradation					1452:1462	higher degradation	1445:1462	higher degradation	1445:1462	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	9	38	theme	laurate	1387:1393	arg1	films					1395:1399	PHB/ esterified PALF-MCC laurate films	1362:1399	PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester	1362:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	4	39	from	influence	531:539	arg1	morphology					616:625	the film surface morphology	599:625	the film surface morphology	599:625	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	4	39	from	influence	531:539	arg1	properties					643:652	biocomposite properties	630:652	biocomposite properties	630:652	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	8	40	theme	PALF-MCC	1140:1147	arg1	laurate					1149:1155	esterified PALF-MCC laurate	1129:1155	esterified PALF-MCC laurate	1129:1155	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	8	40	theme	PALF-MCC	1140:1147	arg1	filler					1162:1167	a filler	1160:1167	a filler in the biocomposite film	1160:1192	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	3	41	theme	lauroyl	485:491	arg1	agent					520:524	an esterifying agent	505:524	an esterifying agent	505:524	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	3	41	theme	lauroyl	485:491	arg1	chloride					493:500	lauroyl chloride	485:500	lauroyl chloride	485:500	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	9	42	theme	%	1410:1410	arg1	ester					1435:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	10	43	attach	derived	1571:1577	arg2	PHB					1535:1537	PHB	1535:1537	PHB	1535:1537	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	10	43	attach	derived	1571:1577	arg1	wastes					1607:1612	pineapple agricultural wastes	1584:1612	pineapple agricultural wastes	1584:1612	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	4	44	from	content	576:582	arg1	morphology					616:625	the film surface morphology	599:625	the film surface morphology	599:625	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	1	45	theme	abundant	159:166	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	45	theme	abundant	159:166	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	4	46	theme	surface	608:614	arg1	morphology					616:625	the film surface morphology	599:625	the film surface morphology	599:625	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	10	47	theme	PALF-MCC	1554:1561	arg1	laurate					1563:1569	esterified PALF-MCC laurate	1543:1569	esterified PALF-MCC laurate	1543:1569	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	6	48	theme	laurate	949:955	arg1	addition					917:924	The addition	913:924	The addition of esterified PALF-MCC laurate	913:955	The addition of esterified PALF-MCC laurate increased the degradation temperature.					
36867618	3	49	theme	esterifying	508:518	arg1	agent					520:524	an esterifying agent	505:524	an esterifying agent	505:524	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	3	49	theme	esterifying	508:518	arg1	chloride					493:500	lauroyl chloride	485:500	lauroyl chloride	485:500	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	5	50	from	decrease	747:754	arg1	crystallinity					759:771	crystallinity	759:771	crystallinity	759:771	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	6	51	theme	esterified	929:938	arg1	laurate					949:955	esterified PALF-MCC laurate	929:955	esterified PALF-MCC laurate	929:955	The addition of esterified PALF-MCC laurate increased the degradation temperature.					
36867618	10	52	from	compostable	1715:1725	arg1	soil					1730:1733	soil	1730:1733	soil	1730:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	4	53	theme	changes	588:594	arg1	influence					531:539	The influence	527:539	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties	527:652	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	10	54	theme	pineapple	1584:1592	arg1	wastes					1607:1612	pineapple agricultural wastes	1584:1612	pineapple agricultural wastes	1584:1612	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	9	55	with	films	1395:1399	arg1	ester					1435:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	5-20% (w/w) PALF-MCC laurate ester	1406:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	2	56	theme	green	286:290	arg1	biocomposites					292:304	fully degradable green biocomposites	269:304	fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC)	269:407	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	5	57	theme	PALF-MCC	871:878	arg1	laurate					880:886	100 wt% esterified PALF-MCC laurate	852:886	100 wt% esterified PALF-MCC laurate	852:886	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	0	58	theme	long-chain	49:58	arg1	acid					66:69	long-chain fatty acid	49:69	long-chain fatty acid	49:69	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	5	59	theme	wt	805:806	arg1	PHB					809:811	100 wt% PHB	801:811	100 wt% PHB displaying the highest values	801:841	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	8	60	theme	pleasant	1209:1216	arg1	value					1218:1222	a pleasant value	1207:1222	a pleasant value of tensile strength and elastic modulus	1207:1262	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	8	61	theme	slight	1274:1279	arg1	increase					1281:1288	a slight increase	1272:1288	a slight increase in elongation	1272:1302	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	1	62	theme	%	213:213	arg1	cellulose					215:223	26.9% cellulose	209:223	26.9% cellulose	209:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	7	63	theme	PALF-MCC	1082:1089	arg1	%					1077:1077	5%	1076:1077	5% of PALF-MCC	1076:1089	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	7	63	theme	PALF-MCC	1082:1089	arg1	PALF-MCC					1082:1089	PALF-MCC	1082:1089	PALF-MCC	1082:1089	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	2	64	theme	study	248:252	arg1	objective					230:238	The objective	226:238	The objective of this study	226:252	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	9	65	theme	100	1489:1491	arg1	%					1492:1492	%	1492:1492	%	1492:1492	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	8	66	theme	strength	1235:1242	arg1	value					1218:1222	a pleasant value	1207:1222	a pleasant value of tensile strength and elastic modulus	1207:1262	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	1	67	theme	Pineapple	130:138	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	67	theme	Pineapple	130:138	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	8	68	theme	elastic	1248:1254	arg1	modulus					1256:1262	elastic modulus	1248:1262	elastic modulus	1248:1262	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	5	69	theme	scanning	715:722	arg1	calorimetry					724:734	differential scanning calorimetry	702:734	differential scanning calorimetry	702:734	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	9	70	theme	100	1501:1503	arg1	%					1504:1504	%	1504:1504	%	1504:1504	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	9	71	theme	esterified	1506:1515	arg1	laurate					1526:1532	100% esterified PALF-MCC laurate	1501:1532	100% esterified PALF-MCC laurate	1501:1532	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	4	72	from	morphology	616:625	arg1	influence					531:539	The influence	527:539	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties	527:652	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	1	73	theme	agricultural	168:179	arg1	fibres					145:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres	130:150	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	1	73	theme	agricultural	168:179	arg1	product					187:193	an abundant agricultural waste product	156:193	an abundant agricultural waste product that contains 26.9% cellulose	156:223	Pineapple leaf fibres are an abundant agricultural waste product that contains 26.9% cellulose.					
36867618	0	74	theme	pineapple	114:122	arg1	leaf					124:127	pineapple leaf	114:127	pineapple leaf	114:127	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	7	75	theme	tensile	1008:1014	arg1	strength					1016:1023	maximum tensile strength	1000:1023	maximum tensile strength	1000:1023	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	9	76	theme	soil	1341:1344	arg1	testing					1353:1359	soil burial testing	1341:1359	soil burial testing	1341:1359	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	10	77	theme	low-cost	1673:1680	arg1	compostable					1715:1725	100% compostable	1710:1725	100% compostable in soil	1710:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	10	77	theme	low-cost	1673:1680	arg1	films					1695:1699	relatively low-cost biocomposite films	1662:1699	relatively low-cost biocomposite films that are 100% compostable in soil	1662:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	5	78	theme	highest	828:834	arg1	values					836:841	the highest values	824:841	the highest values	824:841	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	4	79	theme	laurate	568:574	arg1	content					576:582	the esterified PALF-MCC laurate content	544:582	the esterified PALF-MCC laurate content	544:582	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	7	80	dep	strength	1016:1023	arg1	The					996:998	The	996:998	The	996:998	The maximum tensile strength and elongation at break were exhibited when adding 5% of PALF-MCC.					
36867618	5	81	theme	%	807:807	arg1	PHB					809:811	100 wt% PHB	801:811	100 wt% PHB displaying the highest values	801:841	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	9	82	theme	PALF-MCC	1378:1385	arg1	films					1395:1399	PHB/ esterified PALF-MCC laurate films	1362:1399	PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester	1362:1439	For soil burial testing, PHB/ esterified PALF-MCC laurate films with 5-20% (w/w) PALF-MCC laurate ester had higher degradation than films consisting of 100% PHB or 100% esterified PALF-MCC laurate.					
36867618	8	83	theme	esterified	1129:1138	arg1	laurate					1149:1155	esterified PALF-MCC laurate	1129:1155	esterified PALF-MCC laurate	1129:1155	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	8	83	theme	esterified	1129:1138	arg1	filler					1162:1167	a filler	1160:1167	a filler in the biocomposite film	1160:1192	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	10	84	theme	films	1695:1699	arg1	production					1648:1657	the production	1644:1657	the production of relatively low-cost biocomposite films that are 100% compostable in soil	1644:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	0	85	theme	fatty	60:64	arg1	acid					66:69	long-chain fatty acid	49:69	long-chain fatty acid	49:69	Green composites made of polyhydroxybutyrate and long-chain fatty acid esterified microcrystalline cellulose from pineapple leaf.					
36867618	8	86	from	filler	1162:1167	arg1	film					1189:1192	the biocomposite film	1172:1192	the biocomposite film	1172:1192	The results demonstrated that adding esterified PALF-MCC laurate as a filler in the biocomposite film could retain a pleasant value of tensile strength and elastic modulus whereas a slight increase in elongation can help to enhance flexibility.					
36867618	4	87	theme	esterified	548:557	arg1	content					576:582	the esterified PALF-MCC laurate content	544:582	the esterified PALF-MCC laurate content	544:582	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	2	88	theme	microcrystalline	344:359	arg1	cellulose					361:369	microcrystalline cellulose	344:369	microcrystalline cellulose	344:369	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	5	89	dep	esterified	860:869	arg1	%					858:858	100 wt%	852:858	100 wt%	852:858	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	10	90	theme	%	1713:1713	arg1	compostable					1715:1725	100% compostable	1710:1725	100% compostable in soil	1710:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	10	90	theme	%	1713:1713	arg1	films					1695:1699	relatively low-cost biocomposite films	1662:1699	relatively low-cost biocomposite films that are 100% compostable in soil	1662:1733	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	5	91	theme	esterified	860:869	arg1	laurate					880:886	100 wt% esterified PALF-MCC laurate	852:886	100 wt% esterified PALF-MCC laurate	852:886	The thermal properties obtained by differential scanning calorimetry revealed a decrease in crystallinity for all biocomposites, with 100 wt% PHB displaying the highest values, whereas 100 wt% esterified PALF-MCC laurate showed no crystallinity.					
36867618	3	92	dep	modified	470:477	arg1	surface					462:468	surface	462:468	surface	462:468	To improve compatibility with PHB, the PALF-MCC was surface modified using lauroyl chloride as an esterifying agent.					
36867618	4	93	theme	biocomposite	630:641	arg1	properties					643:652	biocomposite properties	630:652	biocomposite properties	630:652	The influence of the esterified PALF-MCC laurate content and changes in the film surface morphology on biocomposite properties was studied.					
36867618	10	94	theme	esterified	1543:1552	arg1	laurate					1563:1569	esterified PALF-MCC laurate	1543:1569	esterified PALF-MCC laurate	1543:1569	PHB and esterified PALF-MCC laurate derived from pineapple agricultural wastes are particularly suitable for the production of relatively low-cost biocomposite films that are 100% compostable in soil.					
36867618	2	95	theme	leaf	386:389	arg1	PALF-MCC					399:406	PALF-MCC	399:406	PALF-MCC	399:406	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
36867618	2	95	theme	leaf	386:389	arg1	fibres					391:396	pineapple leaf fibres	376:396	pineapple leaf fibres (PALF-MCC)	376:407	The objective of this study was to prepare fully degradable green biocomposites made of polyhydroxybutyrate (PHB) and microcrystalline cellulose from pineapple leaf fibres (PALF-MCC).					
35149100	5	0	theme	erythrocytes	865:876	arg1	absorption					929:938	rapid plasma protein absorption	908:938	rapid plasma protein absorption	908:938	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	0	theme	erythrocytes	865:876	arg1	activation					879:888	activation	879:888	activation of platelets	879:901	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	0	theme	erythrocytes	865:876	arg1	attachment					851:860	attachment	851:860	attachment of erythrocytes	851:876	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	1	theme	Further	720:726	arg1	investigation					728:740	Further investigation	720:740	Further investigation of the hemostatic mechanism	720:768	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	6	2	from	model	1022:1026	arg1	effective					974:982	effective	974:982	effective	974:982	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	4	3	dep	In	579:580	arg1	vitro					582:586	vitro	582:586	vitro	582:586	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	7	4	theme	CS/PVP/Zein	1062:1072	arg1	sponges					1074:1080	the CS/PVP/Zein sponges	1058:1080	the CS/PVP/Zein sponges	1058:1080	Overall, the CS/PVP/Zein sponges exhibited the potential to control trauma-related hemorrhage.					
35149100	3	5	theme	low	558:560	arg1	ratio					572:576	low hemolysis ratio	558:576	low hemolysis ratio	558:576	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	4	6	theme	CS/PVP/Zein	630:640	arg1	sponges					642:648	CS/PVP/Zein sponges	630:648	CS/PVP/Zein sponges	630:648	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	6	7	theme	artery	1003:1008	arg1	model					1022:1026	the rat femoral artery transection model to control bleeding	987:1046	the rat femoral artery transection model to control bleeding	987:1046	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	3	8	theme	CS/PVP/Zein	382:392	arg1	sponges					395:401	chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges	346:401	chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous	346:418	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	6	9	theme	femoral	995:1001	arg1	model					1022:1026	the rat femoral artery transection model to control bleeding	987:1046	the rat femoral artery transection model to control bleeding	987:1046	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	2	10	theme	poor	287:290	arg1	stability					292:300	poor stability	287:300	poor stability	287:300	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	3	11	theme	low	537:539	arg1	cytotoxicity					541:552	low cytotoxicity	537:552	low cytotoxicity	537:552	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	3	12	dep	structure were	420:433	arg1	prepared					435:442	prepared	435:442	prepared	435:442	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	4	13	theme	commercial	693:702	arg1	gauze					713:717	commercial surgical gauze	693:717	commercial surgical gauze	693:717	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	3	14	theme	water	467:471	arg1	capacity					484:491	rapid water absorption capacity	461:491	rapid water absorption capacity	461:491	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	3	15	theme	chitosan/polyvinylpyrrolidone/zein	346:379	arg1	sponges					395:401	chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges	346:401	chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous	346:418	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	2	16	theme	Chitosan	168:175	arg1	sponges					182:188	Chitosan (CS) sponges	168:188	Chitosan (CS) sponges	168:188	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	3	17	theme	absorption	473:482	arg1	capacity					484:491	rapid water absorption capacity	461:491	rapid water absorption capacity	461:491	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	6	18	theme	rat	991:993	arg1	model					1022:1026	the rat femoral artery transection model to control bleeding	987:1046	the rat femoral artery transection model to control bleeding	987:1046	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	2	19	contain	have	190:193	arg1	sponges					182:188	Chitosan (CS) sponges	168:188	Chitosan (CS) sponges	168:188	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	2	19	contain	have	190:193	arg2	advantages					202:211	unique advantages	195:211	unique advantages	195:211	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	5	20	theme	rapid	908:912	arg1	absorption					929:938	rapid plasma protein absorption	908:938	rapid plasma protein absorption	908:938	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	2	21	theme	crosslinking	312:323	arg1	agent					325:329	toxic crosslinking agent	306:329	toxic crosslinking agent	306:329	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	3	22	theme	rapid	461:465	arg1	capacity					484:491	rapid water absorption capacity	461:491	rapid water absorption capacity	461:491	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	5	23	theme	plasma	914:919	arg1	absorption					929:938	rapid plasma protein absorption	908:938	rapid plasma protein absorption	908:938	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	4	24	theme	coagulation	594:604	arg1	experiments					606:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	2	25	theme	toxic	306:310	arg1	agent					325:329	toxic crosslinking agent	306:329	toxic crosslinking agent	306:329	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	3	26	theme	water-triggered	497:511	arg1	property					523:530	water-triggered expanding property	497:530	water-triggered expanding property	497:530	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	3	27	with	sponges	395:401	arg1	macroporous					408:418	macroporous	408:418	macroporous	408:418	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	5	28	theme	CS/PVP/Zein	789:799	arg1	sponges					801:807	the CS/PVP/Zein sponges	785:807	the CS/PVP/Zein sponges	785:807	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	2	29	theme	unique	195:200	arg1	advantages					202:211	unique advantages	195:211	unique advantages	195:211	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	3	30	theme	expanding	513:521	arg1	property					523:530	water-triggered expanding property	497:530	water-triggered expanding property	497:530	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	0	31	theme	composite	65:73	arg1	sponges					86:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	Preparation and evaluation of chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges.					
35149100	0	32	theme	chitosan/polyvinylpyrrolidone/zein	30:63	arg1	sponges					86:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	Preparation and evaluation of chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges.					
35149100	4	33	theme	In	579:580	arg1	experiments					606:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	6	34	from	effective	974:982	arg1	model					1022:1026	the rat femoral artery transection model to control bleeding	987:1046	the rat femoral artery transection model to control bleeding	987:1046	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	2	35	theme	bleeding	241:248	arg1	treatment					220:228	the treatment	216:228	the treatment of massive bleeding	216:248	Chitosan (CS) sponges have unique advantages in the treatment of massive bleeding, but their application is limited by poor stability and toxic crosslinking agent.					
35149100	0	36	theme	sponges	86:92	arg1	evaluation					16:25	evaluation	16:25	evaluation	16:25	Preparation and evaluation of chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges.					
35149100	0	36	theme	sponges	86:92	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and evaluation of chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges.					
35149100	5	37	theme	hemostatic	749:758	arg1	mechanism					760:768	the hemostatic mechanism	745:768	the hemostatic mechanism	745:768	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	1	38	theme	leading	143:149	arg1	causes					151:156	the leading causes	139:156	the leading causes of death	139:165	Trauma-related excessive bleeding is one of the leading causes of death.					
35149100	0	39	theme	hemostatic	75:84	arg1	sponges					86:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges	30:92	Preparation and evaluation of chitosan/polyvinylpyrrolidone/zein composite hemostatic sponges.					
35149100	4	40	theme	blood	588:592	arg1	experiments					606:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments	579:616	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	5	41	theme	mechanism	760:768	arg1	investigation					728:740	Further investigation	720:740	Further investigation of the hemostatic mechanism	720:768	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	6	42	theme	transection	1010:1020	arg1	model					1022:1026	the rat femoral artery transection model to control bleeding	987:1046	the rat femoral artery transection model to control bleeding	987:1046	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	6	43	theme	Prepared	941:948	arg1	sponges					950:956	Prepared sponges	941:956	Prepared sponges	941:956	Prepared sponges were also found effective in the rat femoral artery transection model to control bleeding.					
35149100	1	44	theme	causes	151:156	arg1	one					132:134	one	132:134	one	132:134	Trauma-related excessive bleeding is one of the leading causes of death.					
35149100	1	44	theme	causes	151:156	arg1	causes					151:156	the leading causes	139:156	the leading causes of death	139:165	Trauma-related excessive bleeding is one of the leading causes of death.					
35149100	4	45	dep	faster	681:686	arg1	clot					656:659	clot	656:659	clot	656:659	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	4	45	dep	faster	681:686	arg1	blood					661:665	blood	661:665	blood	661:665	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	7	46	theme	trauma-related	1117:1130	arg1	hemorrhage					1132:1141	trauma-related hemorrhage	1117:1141	trauma-related hemorrhage	1117:1141	Overall, the CS/PVP/Zein sponges exhibited the potential to control trauma-related hemorrhage.					
35149100	1	47	theme	death	161:165	arg1	causes					151:156	the leading causes	139:156	the leading causes of death	139:165	Trauma-related excessive bleeding is one of the leading causes of death.					
35149100	4	48	theme	surgical	704:711	arg1	gauze					713:717	commercial surgical gauze	693:717	commercial surgical gauze	693:717	In vitro blood coagulation experiments showed that CS/PVP/Zein sponges could clot blood significantly faster than commercial surgical gauze.					
35149100	3	49	theme	hemolysis	562:570	arg1	ratio					572:576	low hemolysis ratio	558:576	low hemolysis ratio	558:576	In this work, chitosan/polyvinylpyrrolidone/zein (CS/PVP/Zein) sponges with macroporous structure were prepared, which exhibited rapid water absorption capacity and water-triggered expanding property with low cytotoxicity and low hemolysis ratio.					
35149100	5	50	theme	platelets	893:901	arg1	absorption					929:938	rapid plasma protein absorption	908:938	rapid plasma protein absorption	908:938	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	50	theme	platelets	893:901	arg1	activation					879:888	activation	879:888	activation of platelets	879:901	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	50	theme	platelets	893:901	arg1	attachment					851:860	attachment	851:860	attachment of erythrocytes	851:876	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
35149100	5	51	theme	protein	921:927	arg1	absorption					929:938	rapid plasma protein absorption	908:938	rapid plasma protein absorption	908:938	Further investigation of the hemostatic mechanism suggested that the CS/PVP/Zein sponges could accelerate coagulation by promoting attachment of erythrocytes, activation of platelets, and rapid plasma protein absorption.					
36089086	1	0	theme	casting	336:342	arg1	method					344:349	a solution casting method	325:349	a solution casting method	325:349	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	2	1	theme	developed	356:364	arg1	films					394:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	0	2	theme	glucan	73:78	arg1	complexes					80:88	chitin and glucan complexes	62:88	chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat	62:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	4	3	theme	barrier	693:699	arg1	properties					701:710	improved light barrier properties	678:710	improved light barrier properties	678:710	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	1	4	theme	glucan	264:269	arg1	CGCs					282:285	CGCs	282:285	CGCs	282:285	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	1	4	theme	glucan	264:269	arg1	complexes					271:279	chitin and glucan complexes	253:279	chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method	253:349	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	2	5	theme	antimicrobial	499:511	arg1	properties					513:522	antimicrobial properties	499:522	antimicrobial properties	499:522	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	5	theme	antimicrobial	499:511	arg1	terms					422:426	terms	422:426	terms of surface	422:437	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	7	6	theme	samples	1151:1157	arg1	shelf-life					1129:1138	The shelf-life	1125:1138	The shelf-life of chicken samples wrapped in the developed film	1125:1187	The shelf-life of chicken samples wrapped in the developed film was extended at least 40 % compared to the control sample.					
36089086	5	7	theme	antibacterial	910:922	arg1	activity					924:931	antibacterial activity	910:931	antibacterial activity against Staphylococcus aureus	910:961	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	4	8	theme	surface	655:661	arg1	morphology					663:672	the surface morphology	651:672	the surface morphology	651:672	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	6	9	theme	microbial	1021:1029	arg1	properties					1031:1040	the microbial properties	1017:1040	the microbial properties of the fresh chicken breast	1017:1068	Afterward, the microbial properties of the fresh chicken breast were examined during refrigerated storage for 10 days.					
36089086	7	10	theme	control	1232:1238	arg1	sample					1240:1245	the control sample	1228:1245	the control sample	1228:1245	The shelf-life of chicken samples wrapped in the developed film was extended at least 40 % compared to the control sample.					
36089086	8	11	theme	promising	1316:1324	arg1	material					1357:1364	a promising biodegradable active packaging material	1314:1364	a promising biodegradable active packaging material	1314:1364	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	8	11	theme	promising	1316:1324	arg1	curcumin					1263:1270	curcumin	1263:1270	curcumin incorporated CGC based films	1263:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	8	12	theme	based	1289:1293	arg1	films					1295:1299	CGC based films	1285:1299	CGC based films	1285:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	4	13	theme	films	776:780	arg1	properties					701:710	improved light barrier properties	678:710	improved light barrier properties	678:710	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	4	13	theme	films	776:780	arg1	morphology					663:672	the surface morphology	651:672	the surface morphology	651:672	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	4	13	theme	films	776:780	arg1	content					761:767	total phenolic content	746:767	total phenolic content of the films	746:780	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	4	13	theme	films	776:780	arg1	activity					732:739	radical scavenging activity	713:739	radical scavenging activity	713:739	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	1	14	theme	Composite	168:176	arg1	films					178:182	Composite films	168:182	Composite films	168:182	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	7	15	theme	developed	1174:1182	arg1	film					1184:1187	the developed film	1170:1187	the developed film	1170:1187	The shelf-life of chicken samples wrapped in the developed film was extended at least 40 % compared to the control sample.					
36089086	7	16	theme	chicken	1143:1149	arg1	samples					1151:1157	chicken samples	1143:1157	chicken samples wrapped in the developed film	1143:1187	The shelf-life of chicken samples wrapped in the developed film was extended at least 40 % compared to the control sample.					
36089086	5	17	theme	different	811:819	arg1	concentrations					821:834	different concentrations	811:834	different concentrations of curcumin	811:846	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	2	18	theme	CGC/Cu	386:391	arg1	films					394:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	3	19	theme	films	556:560	arg1	biodegradability					529:544	The biodegradability	525:544	The biodegradability of CGC/Cu films	525:560	The biodegradability of CGC/Cu films was determined in soil for 14 days.					
36089086	8	20	theme	CGC	1285:1287	arg1	films					1295:1299	CGC based films	1285:1299	CGC based films	1285:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	2	21	theme	surface	431:437	arg1	terms					422:426	terms	422:426	terms of surface	422:437	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	barrier					461:467	barrier	461:467	barrier	461:467	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	mechanical					470:479	mechanical	470:479	mechanical	470:479	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	properties					513:522	antimicrobial properties	499:522	antimicrobial properties	499:522	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	optical					440:446	optical	440:446	optical	440:446	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	structural					449:458	structural	449:458	structural	449:458	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	2	21	theme	surface	431:437	arg1	antioxidant					482:492	antioxidant	482:492	antioxidant	482:492	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	8	22	theme	meat	1395:1398	arg1	products					1400:1407	meat products	1395:1407	meat products	1395:1407	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	2	23	theme	CGC	381:383	arg1	films					394:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	0	24	theme	active	127:132	arg1	packaging					134:142	active packaging	127:142	active packaging of chicken breast meat	127:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	4	25	theme	phenolic	752:759	arg1	content					761:767	total phenolic content	746:767	total phenolic content of the films	746:780	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	5	26	theme	developed	989:997	arg1	films					999:1003	the developed films	985:1003	the developed films	985:1003	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	4	27	theme	curcumin	619:626	arg1	incorporation					602:614	The incorporation	598:614	The incorporation of curcumin	598:626	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	0	28	theme	curcumin	15:22	arg1	Development					0:10	Development	0:10	Development of curcumin	0:22	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	3	29	theme	CGC/Cu	549:554	arg1	films					556:560	CGC/Cu films	549:560	CGC/Cu films	549:560	The biodegradability of CGC/Cu films was determined in soil for 14 days.					
36089086	8	30	theme	products	1400:1407	arg1	shelf-life					1381:1390	the shelf-life	1377:1390	the shelf-life of meat products	1377:1407	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	4	31	theme	light	687:691	arg1	properties					701:710	improved light barrier properties	678:710	improved light barrier properties	678:710	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	5	32	theme	antibacterial	855:867	arg1	activity					869:876	antibacterial activity	855:876	antibacterial activity	855:876	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	8	33	theme	packaging	1347:1355	arg1	material					1357:1364	a promising biodegradable active packaging material	1314:1364	a promising biodegradable active packaging material	1314:1364	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	8	33	theme	packaging	1347:1355	arg1	curcumin					1263:1270	curcumin	1263:1270	curcumin incorporated CGC based films	1263:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	1	34	theme	different	211:219	arg1	concentrations					221:234	different concentrations	211:234	different concentrations of curcumin	211:246	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	0	35	theme	composite	37:45	arg1	films					47:51	composite films	37:51	composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat	37:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	8	36	theme	active	1340:1345	arg1	material					1357:1364	a promising biodegradable active packaging material	1314:1364	a promising biodegradable active packaging material	1314:1364	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	8	36	theme	active	1340:1345	arg1	curcumin					1263:1270	curcumin	1263:1270	curcumin incorporated CGC based films	1263:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	5	37	theme	CGC/Cu	787:792	arg1	films					794:798	The CGC/Cu films	783:798	The CGC/Cu films containing different concentrations of curcumin	783:846	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	0	38	theme	breast	155:160	arg1	meat					162:165	chicken breast meat	147:165	chicken breast meat	147:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	5	39	contain	containing	800:809	arg1	films					794:798	The CGC/Cu films	783:798	The CGC/Cu films containing different concentrations of curcumin	783:846	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	5	39	contain	containing	800:809	arg2	concentrations					821:834	different concentrations	811:834	different concentrations of curcumin	811:846	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	4	40	theme	radical	713:719	arg1	activity					732:739	radical scavenging activity	713:739	radical scavenging activity	713:739	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	0	41	theme	chicken	147:153	arg1	meat					162:165	chicken breast meat	147:165	chicken breast meat	147:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	6	42	theme	chicken	1055:1061	arg1	breast					1063:1068	the fresh chicken breast	1045:1068	the fresh chicken breast	1045:1068	Afterward, the microbial properties of the fresh chicken breast were examined during refrigerated storage for 10 days.					
36089086	4	43	theme	improved	678:685	arg1	properties					701:710	improved light barrier properties	678:710	improved light barrier properties	678:710	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	8	44	theme	biodegradable	1326:1338	arg1	material					1357:1364	a promising biodegradable active packaging material	1314:1364	a promising biodegradable active packaging material	1314:1364	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	8	44	theme	biodegradable	1326:1338	arg1	curcumin					1263:1270	curcumin	1263:1270	curcumin incorporated CGC based films	1263:1299	In conclusion, curcumin incorporated CGC based films can serve as a promising biodegradable active packaging material to improve the shelf-life of meat products.					
36089086	6	45	theme	breast	1063:1068	arg1	properties					1031:1040	the microbial properties	1017:1040	the microbial properties of the fresh chicken breast	1017:1068	Afterward, the microbial properties of the fresh chicken breast were examined during refrigerated storage for 10 days.					
36089086	0	46	theme	meat	162:165	arg1	packaging					134:142	active packaging	127:142	active packaging of chicken breast meat	127:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	6	47	theme	refrigerated	1091:1102	arg1	storage					1104:1110	refrigerated storage	1091:1110	refrigerated storage for 10 days	1091:1122	Afterward, the microbial properties of the fresh chicken breast were examined during refrigerated storage for 10 days.					
36089086	4	48	theme	total	746:750	arg1	content					761:767	total phenolic content	746:767	total phenolic content of the films	746:780	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	4	49	theme	scavenging	721:730	arg1	activity					732:739	radical scavenging activity	713:739	radical scavenging activity	713:739	The incorporation of curcumin significantly affected the surface morphology and improved light barrier properties, radical scavenging activity, and total phenolic content of the films.					
36089086	1	50	theme	curcumin	239:246	arg1	concentrations					221:234	different concentrations	211:234	different concentrations of curcumin	211:246	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	5	51	theme	curcumin	839:846	arg1	concentrations					821:834	different concentrations	811:834	different concentrations of curcumin	811:846	The CGC/Cu films containing different concentrations of curcumin showed antibacterial activity against Escherichia coli, while antibacterial activity against Staphylococcus aureus was not observed with the developed films.					
36089086	2	52	theme	doped	375:379	arg1	films					394:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	6	53	theme	fresh	1049:1053	arg1	breast					1063:1068	the fresh chicken breast	1045:1068	the fresh chicken breast	1045:1068	Afterward, the microbial properties of the fresh chicken breast were examined during refrigerated storage for 10 days.					
36089086	0	54	theme	chitin	62:67	arg1	complexes					80:88	chitin and glucan complexes	62:88	chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat	62:165	Development of curcumin incorporated composite films based on chitin and glucan complexes extracted from Agaricus bisporus for active packaging of chicken breast meat.					
36089086	1	55	theme	solution	327:334	arg1	method					344:349	a solution casting method	325:349	a solution casting method	325:349	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	2	56	theme	curcumin	366:373	arg1	films					394:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films	352:398	The developed curcumin doped CGC (CGC/Cu) films were characterized in terms of surface, optical, structural, barrier, mechanical, antioxidant, and antimicrobial properties.					
36089086	1	57	theme	chitin	253:258	arg1	CGCs					282:285	CGCs	282:285	CGCs	282:285	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36089086	1	57	theme	chitin	253:258	arg1	complexes					271:279	chitin and glucan complexes	253:279	chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method	253:349	Composite films were prepared by combining different concentrations of curcumin with chitin and glucan complexes (CGCs) extracted from Agaricus bisporus via a solution casting method.					
36224466	0	0	theme	aqueous	106:112	arg1	solution					114:121	aqueous solution	106:121	aqueous solution	106:121	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	4	1	theme	maximum	937:943	arg1	capacity					970:977	a maximum heterogeneous adsorption capacity	935:977	a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1	935:1002	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	5	2	theme	electrostatic	1223:1235	arg1	attractions					1237:1247	electrostatic attractions	1223:1247	electrostatic attractions between the protonated amine	1223:1276	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	1	3	theme	serious	246:252	arg1	interest					254:261	serious interest	246:261	serious interest	246:261	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	5	4	dep	infrared	1173:1180	arg1	FTIR					1183:1186	FTIR	1183:1186	FTIR	1183:1186	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	3	5	dep	pH	725:726	arg1	e.g.					719:722	e.g.	719:722	e.g.	719:722	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	2	6	theme	 from	597:601	arg1	water					603:607	perfluorobutanesulfonate (PFBS) from water	566:607	perfluorobutanesulfonate (PFBS) from water	566:607	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	5	7	theme	β-CD	1405:1408	arg1	cavity					1410:1415	β-CD cavity	1405:1415	β-CD cavity in adsorption	1405:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	8	from	cavity	1410:1415	arg1	adsorption					1420:1429	adsorption	1420:1429	adsorption	1420:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	9	theme	attractions	1237:1247	arg1	molecule					1310:1317	the negatively charged PFBS molecule	1282:1317	the negatively charged PFBS molecule (especially	1282:1329	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	9	theme	attractions	1237:1247	arg1	role					1215:1218	the role	1211:1218	the role of electrostatic attractions between the protonated amine	1211:1276	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	3	10	theme	adsorption	787:796	arg1	kinetics					798:805	faster adsorption kinetics	780:805	faster adsorption kinetics	780:805	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	5	11	dep	Fourier	1155:1161	arg1	transform					1163:1171	transform	1163:1171	transform	1163:1171	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	2	12	dep	cross-linking	446:458	arg1	chitosan					460:467	chitosan	460:467	chitosan	460:467	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	1	13	from	existence	174:182	arg1	water					234:238	water	234:238	water	234:238	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	6	14	from	decline	1525:1531	arg1	efficiency					1547:1556	adsorption efficiency	1536:1556	adsorption efficiency	1536:1556	Additionally, the synthesized adsorbent was recovered using methanol without any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles.					
36224466	3	15	theme	rate	829:832	arg1	k2					844:845	k2	844:845	k2	844:845	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	3	15	theme	rate	829:832	arg1	constant					834:841	the rate constant	825:841	the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1	825:877	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	5	16	theme	dispersive	1134:1143	arg1	X-ray					1145:1149	energy dispersive X-ray	1127:1149	energy dispersive X-ray	1127:1149	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	2	17	theme	PFBS	592:595	arg1	water					603:607	perfluorobutanesulfonate (PFBS) from water	566:607	perfluorobutanesulfonate (PFBS) from water	566:607	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	0	18	link	cross-linked	9:20	arg1	β-cyclodextrin					22:35	Chitosan cross-linked β-cyclodextrin polymeric adsorbent	0:55	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.	0:168	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	4	19	theme	heterogeneous	945:957	arg1	capacity					970:977	a maximum heterogeneous adsorption capacity	935:977	a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1	935:1002	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	4	20	theme	Sips	919:922	arg1	model					924:928	the Sips model	915:928	the Sips model	915:928	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	1	21	theme	effective	344:352	arg1	adsorption					327:336	adsorption	327:336	adsorption	327:336	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	1	21	theme	effective	344:352	arg1	approach					354:361	an effective approach	341:361	an effective approach for the PFASs removal	341:383	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	3	22	theme	0.001 ± 3×10-4 g mg-1 min-1	851:877	arg1	k2					844:845	k2	844:845	k2	844:845	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	3	22	theme	0.001 ± 3×10-4 g mg-1 min-1	851:877	arg1	constant					834:841	the rate constant	825:841	the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1	825:877	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	0	23	theme	adsorption	124:133	arg1	kinetics					135:142	adsorption kinetics	124:142	adsorption kinetics	124:142	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	3	24	theme	faster	780:785	arg1	kinetics					798:805	faster adsorption kinetics	780:805	faster adsorption kinetics	780:805	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	5	25	theme	host-guest	1368:1377	arg1	formations					1389:1398	host-guest inclusion formations	1368:1398	host-guest inclusion formations with β-CD cavity in adsorption	1368:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	4	26	theme	135.70 ± 25.70 mg g-1	982:1002	arg1	capacity					970:977	a maximum heterogeneous adsorption capacity	935:977	a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1	935:1002	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	1	27	theme	per-	187:190	arg1	PFASs					224:228	PFASs	224:228	PFASs	224:228	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	1	27	theme	per-	187:190	arg1	substances					212:221	per- and polyfluoroalkyl substances	187:221	per- and polyfluoroalkyl substances (PFASs)	187:229	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	0	28	theme	cross-linked	9:20	arg1	β-cyclodextrin					22:35	Chitosan cross-linked β-cyclodextrin polymeric adsorbent	0:55	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.	0:168	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	3	29	theme	acidic	701:706	arg1	pH					725:726	pH 2.0	725:730	pH 2.0	725:730	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	3	29	theme	acidic	701:706	arg1	condition					708:716	a more acidic condition	694:716	a more acidic condition (e.g., pH 2.0)	694:731	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	4	30	theme	Adsorption	880:889	arg1	data					900:903	Adsorption isotherm data	880:903	Adsorption isotherm data	880:903	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	5	31	theme	inclusion	1379:1387	arg1	formations					1389:1398	host-guest inclusion formations	1368:1398	host-guest inclusion formations with β-CD cavity in adsorption	1368:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	6	32	theme	significant	1513:1523	arg1	decline					1525:1531	any significant decline	1509:1531	any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles	1509:1612	Additionally, the synthesized adsorbent was recovered using methanol without any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles.					
36224466	0	33	theme	Chitosan	0:7	arg1	β-cyclodextrin					22:35	Chitosan cross-linked β-cyclodextrin polymeric adsorbent	0:55	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.	0:168	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	5	34	with	formations	1389:1398	arg1	cavity					1410:1415	β-CD cavity	1405:1415	β-CD cavity in adsorption	1405:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	1	35	theme	polyfluoroalkyl	196:210	arg1	PFASs					224:228	PFASs	224:228	PFASs	224:228	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	1	35	theme	polyfluoroalkyl	196:210	arg1	substances					212:221	per- and polyfluoroalkyl substances	187:221	per- and polyfluoroalkyl substances (PFASs)	187:229	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	0	36	theme	polymeric	37:45	arg1	β-cyclodextrin					22:35	Chitosan cross-linked β-cyclodextrin polymeric adsorbent	0:55	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.	0:168	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	1	37	theme	toxic	276:280	arg1	nature					315:320	their toxic, bioaccumulative, and persistent nature	270:320	their toxic, bioaccumulative, and persistent nature	270:320	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	2	38	theme	removal	542:548	arg1	performance					550:560	its removal performance	538:560	its removal performance for perfluorobutanesulfonate (PFBS) from water	538:607	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	4	39	theme	β-CD	1067:1070	arg1	cavities					1072:1079	electron-deficient β-CD cavities	1048:1079	electron-deficient β-CD cavities	1048:1079	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	1	40	theme	substances	212:221	arg1	existence					174:182	The existence	170:182	The existence of per- and polyfluoroalkyl substances (PFASs) in water	170:238	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	5	41	with	role	1215:1218	arg1	formations					1389:1398	host-guest inclusion formations	1368:1398	host-guest inclusion formations with β-CD cavity in adsorption	1368:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	41	with	role	1215:1218	arg1	side					1347:1350	sulfonate side	1337:1350	sulfonate side (N-H--O-S))	1337:1362	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	41	with	role	1215:1218	arg1	N-H--O-S					1353:1360	N-H--O-S	1353:1360	N-H--O-S	1353:1360	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	7	42	theme	PFBS	1725:1728	arg1	removal					1714:1720	the removal	1710:1720	the removal of PFBS from water	1710:1739	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	5	43	theme	charged	1297:1303	arg1	molecule					1310:1317	the negatively charged PFBS molecule	1282:1317	the negatively charged PFBS molecule (especially	1282:1329	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	2	44	theme	present	393:399	arg1	study					401:405	the present study	389:405	the present study	389:405	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	4	45	theme	adsorption	959:968	arg1	capacity					970:977	a maximum heterogeneous adsorption capacity	935:977	a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1	935:1002	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	1	46	theme	bioaccumulative	283:297	arg1	nature					315:320	their toxic, bioaccumulative, and persistent nature	270:320	their toxic, bioaccumulative, and persistent nature	270:320	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	1	47	theme	PFASs	371:375	arg1	removal					377:383	the PFASs removal	367:383	the PFASs removal	367:383	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	5	48	theme	PFBS	1305:1308	arg1	molecule					1310:1317	the negatively charged PFBS molecule	1282:1317	the negatively charged PFBS molecule (especially	1282:1329	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	0	49	theme	adsorbent	47:55	arg1	β-cyclodextrin					22:35	Chitosan cross-linked β-cyclodextrin polymeric adsorbent	0:55	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.	0:168	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	4	50	theme	isotherm	891:898	arg1	data					900:903	Adsorption isotherm data	880:903	Adsorption isotherm data	880:903	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	7	51	from	water	1735:1739	arg1	removal					1714:1720	the removal	1710:1720	the removal of PFBS from water	1710:1739	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	5	52	theme	infrared	1173:1180	arg1	spectroscopy					1189:1200	infrared (FTIR) spectroscopy	1173:1200	infrared (FTIR) spectroscopy	1173:1200	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	3	53	theme	higher	736:741	arg1	efficiency					751:760	a higher removal efficiency	734:760	a higher removal efficiency	734:760	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	1	54	theme	persistent	304:313	arg1	nature					315:320	their toxic, bioaccumulative, and persistent nature	270:320	their toxic, bioaccumulative, and persistent nature	270:320	The existence of per- and polyfluoroalkyl substances (PFASs) in water is of serious interest due to their toxic, bioaccumulative, and persistent nature, and adsorption is an effective approach for the PFASs removal.					
36224466	2	55	theme	perfluorobutanesulfonate	566:589	arg1	water					603:607	perfluorobutanesulfonate (PFBS) from water	566:607	perfluorobutanesulfonate (PFBS) from water	566:607	In the present study, we developed a polymeric adsorbent by cross-linking chitosan and β-cyclodextrin using glutaraldehyde (Chi-Glu-β-CD) and evaluated its removal performance for perfluorobutanesulfonate (PFBS) from water.					
36224466	6	56	theme	adsorption/desorption	1585:1605	arg1	cycles					1607:1612	four continuous adsorption/desorption cycles	1569:1612	four continuous adsorption/desorption cycles	1569:1612	Additionally, the synthesized adsorbent was recovered using methanol without any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles.					
36224466	6	57	theme	adsorption	1536:1545	arg1	efficiency					1547:1556	adsorption efficiency	1536:1556	adsorption efficiency	1536:1556	Additionally, the synthesized adsorbent was recovered using methanol without any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles.					
36224466	3	58	theme	solution	675:682	arg1	pH					684:685	solution pH	675:685	solution pH	675:685	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	7	59	from	adsorbent	1697:1705	arg1	removal					1714:1720	the removal	1710:1720	the removal of PFBS from water	1710:1739	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	6	60	theme	continuous	1574:1583	arg1	cycles					1607:1612	four continuous adsorption/desorption cycles	1569:1612	four continuous adsorption/desorption cycles	1569:1612	Additionally, the synthesized adsorbent was recovered using methanol without any significant decline in adsorption efficiency even after four continuous adsorption/desorption cycles.					
36224466	5	61	theme	protonated	1261:1270	arg1	amine					1272:1276	the protonated amine	1257:1276	the protonated amine	1257:1276	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	62	with	side	1347:1350	arg1	cavity					1410:1415	β-CD cavity	1405:1415	β-CD cavity in adsorption	1405:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	7	63	theme	Chi-Glu-β-CD	1653:1664	arg1	adsorbent					1697:1705	adsorbent	1697:1705	adsorbent	1697:1705	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	7	63	theme	Chi-Glu-β-CD	1653:1664	arg1	composite					1666:1674	the Chi-Glu-β-CD composite	1649:1674	the Chi-Glu-β-CD composite	1649:1674	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	5	64	with	molecule	1310:1317	arg1	formations					1389:1398	host-guest inclusion formations	1368:1398	host-guest inclusion formations with β-CD cavity in adsorption	1368:1429	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	64	with	molecule	1310:1317	arg1	side					1347:1350	sulfonate side	1337:1350	sulfonate side (N-H--O-S))	1337:1362	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	64	with	molecule	1310:1317	arg1	N-H--O-S					1353:1360	N-H--O-S	1353:1360	N-H--O-S	1353:1360	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	0	65	dep	β-cyclodextrin	22:35	arg1	isotherm					145:152	isotherm	145:152	isotherm	145:152	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	0	65	dep	β-cyclodextrin	22:35	arg1	mechanism					159:167	mechanism	159:167	mechanism	159:167	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	0	65	dep	β-cyclodextrin	22:35	arg1	kinetics					135:142	adsorption kinetics	124:142	adsorption kinetics	124:142	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	4	66	theme	electron-deficient	1048:1065	arg1	cavities					1072:1079	electron-deficient β-CD cavities	1048:1079	electron-deficient β-CD cavities	1048:1079	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	0	67	theme	perfluorobutanesulfonate	76:99	arg1	removal					65:71	the removal	61:71	the removal of perfluorobutanesulfonate from aqueous solution	61:121	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	0	68	from	solution	114:121	arg1	removal					65:71	the removal	61:71	the removal of perfluorobutanesulfonate from aqueous solution	61:121	Chitosan cross-linked β-cyclodextrin polymeric adsorbent for the removal of perfluorobutanesulfonate from aqueous solution: adsorption kinetics, isotherm, and mechanism.					
36224466	5	69	theme	sulfonate	1337:1345	arg1	side					1347:1350	sulfonate side	1337:1350	sulfonate side (N-H--O-S))	1337:1362	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	5	69	theme	sulfonate	1337:1345	arg1	N-H--O-S					1353:1360	N-H--O-S	1353:1360	N-H--O-S	1353:1360	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	3	70	theme	removal	743:749	arg1	efficiency					751:760	a higher removal efficiency	734:760	a higher removal efficiency	734:760	The results indicate that the performance was highly affected by solution pH; under a more acidic condition (e.g., pH 2.0), a higher removal efficiency was detected, and faster adsorption kinetics was observed with the rate constant (k2) of 0.001 ± 3×10-4 g mg-1 min-1.					
36224466	5	71	theme	adsorption	1086:1095	arg1	mechanism					1097:1105	The adsorption mechanism	1082:1105	The adsorption mechanism	1082:1105	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36224466	7	72	from	removal	1714:1720	arg1	adsorbent					1697:1705	adsorbent	1697:1705	adsorbent	1697:1705	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	7	72	from	removal	1714:1720	arg1	composite					1666:1674	the Chi-Glu-β-CD composite	1649:1674	the Chi-Glu-β-CD composite	1649:1674	All these findings suggested that the Chi-Glu-β-CD composite could be a promising adsorbent in the removal of PFBS from water.					
36224466	4	73	theme	protonated	1021:1030	arg1	amine					1032:1036	protonated amine	1021:1036	protonated amine (NH+)	1021:1042	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	4	73	theme	protonated	1021:1030	arg1	NH+					1039:1041	NH+	1039:1041	NH+	1039:1041	Adsorption isotherm data agreed to the Sips model with a maximum heterogeneous adsorption capacity of 135.70 ± 25.70 mg g-1, probably due to protonated amine (NH+) and electron-deficient β-CD cavities.					
36224466	5	74	theme	energy	1127:1132	arg1	X-ray					1145:1149	energy dispersive X-ray	1127:1149	energy dispersive X-ray	1127:1149	The adsorption mechanism was confirmed using energy dispersive X-ray and Fourier transform infrared (FTIR) spectroscopy, showing the role of electrostatic attractions between the protonated amine and the negatively charged PFBS molecule (especially, with sulfonate side (N-H--O-S)) and host-guest inclusion formations with β-CD cavity in adsorption.					
36894059	4	0	theme	polysaccharide	551:564	arg1	alginate					566:573	polysaccharide alginate	551:573	polysaccharide alginate	551:573	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	1	theme	biological	655:664	arg1	patch					666:670	the biological patch	651:670	the biological patch	651:670	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	2	theme	chondroitin	579:589	arg1	sulfate					591:597	chondroitin sulfate	579:597	chondroitin sulfate	579:597	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	2	3	theme	UV	390:391	arg1	irradiation					394:404	ultraviolet (UV) irradiation	377:404	ultraviolet (UV) irradiation	377:404	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	5	4	theme	acrylylated	817:827	arg1	VEGF					829:832	acrylylated VEGF	817:832	acrylylated VEGF	817:832	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	2	5	theme	endothelial	338:348	arg1	factor					357:362	vascular endothelial growth factor	329:362	vascular endothelial growth factor (VEGF)	329:369	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	5	theme	endothelial	338:348	arg1	VEGF					365:368	VEGF	365:368	VEGF	365:368	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	0	6	link	double-crosslinked	14:31	arg1	sulfate					65:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	2	7	theme	vascular	329:336	arg1	factor					357:362	vascular endothelial growth factor	329:362	vascular endothelial growth factor (VEGF)	329:369	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	7	theme	vascular	329:336	arg1	VEGF					365:368	VEGF	365:368	VEGF	365:368	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	6	8	theme	wound	1119:1123	arg1	healing					1125:1131	diabetic wound healing	1110:1131	diabetic wound healing	1110:1131	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	4	9	theme	mechanical	776:785	arg1	properties					787:796	its mechanical properties	772:796	its mechanical properties	772:796	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	5	10	theme	factors	957:963	arg1	step					922:925	the step	918:925	the step of chemically coupling growth factors	918:963	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	4	11	theme	biological	540:549	arg1	biomaterials					625:636	biomaterials	625:636	biomaterials	625:636	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	11	theme	biological	540:549	arg1	methacryloyl					599:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	12	used	used	617:620	arg2	biomaterials					625:636	biomaterials	625:636	biomaterials	625:636	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	12	used	used	617:620	arg2	methacryloyl					599:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	13	theme	calcium	706:712	arg1	crosslinking					718:729	calcium ion crosslinking	706:729	calcium ion crosslinking	706:729	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	3	14	theme	patches	487:493	arg1	composition					472:482	composition	472:482	composition	472:482	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	3	14	theme	patches	487:493	arg1	structure					458:466	structure	458:466	structure	458:466	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	0	15	theme	double-crosslinked	14:31	arg1	sulfate					65:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	3	16	theme	3D	407:408	arg1	technology					419:428	3D printing technology	407:428	3D printing technology	407:428	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	1	17	theme	chronic	117:123	arg1	healing					131:137	chronic wound healing	117:137	chronic wound healing	117:137	Improving chronic wound healing remains a challenge in the clinical practice.					
36894059	0	18	theme	3D-bioprinted	0:12	arg1	sulfate					65:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	6	19	theme	diabetic	1110:1117	arg1	healing					1125:1131	diabetic wound healing	1110:1131	diabetic wound healing	1110:1131	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	3	20	dep	structure	458:466	arg1	the					454:456	the	454:456	the	454:456	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	1	21	theme	wound	125:129	arg1	healing					131:137	chronic wound healing	117:137	chronic wound healing	117:137	Improving chronic wound healing remains a challenge in the clinical practice.					
36894059	6	22	theme	other	1137:1141	arg1	applications					1162:1173	other tissue engineering applications	1137:1173	other tissue engineering applications	1137:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	5	23	theme	VEGF	979:982	arg1	time					992:995	VEGF release time	979:995	VEGF release time	979:995	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	0	24	theme	alginate/chondroitin	44:63	arg1	sulfate					65:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	1	25	from	challenge	149:157	arg1	practice					175:182	the clinical practice	162:182	the clinical practice	162:182	Improving chronic wound healing remains a challenge in the clinical practice.					
36894059	2	26	theme	factor	357:362	arg1	crosslinking					313:324	the photocovalent crosslinking	295:324	the photocovalent crosslinking of vascular endothelial growth factor (VEGF)	295:369	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	27	link	double-crosslinked	213:230	arg1	patches					257:263	double-crosslinked angiogenic 3D-bioprinted patches	213:263	double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing	213:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	0	28	theme	angiogenic	33:42	arg1	sulfate					65:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate	0:71	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	2	29	theme	growth	350:355	arg1	factor					357:362	vascular endothelial growth factor	329:362	vascular endothelial growth factor (VEGF)	329:369	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	29	theme	growth	350:355	arg1	VEGF					365:368	VEGF	365:368	VEGF	365:368	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	5	30	theme	release	984:990	arg1	time					992:995	VEGF release time	979:995	VEGF release time	979:995	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	6	31	theme	ideal	1089:1093	arg1	patches					1077:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	31	theme	ideal	1089:1093	arg1	candidates					1095:1104	ideal candidates	1089:1104	ideal candidates for diabetic wound healing and other tissue engineering applications	1089:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	2	32	theme	wound	278:282	arg1	healing					284:290	diabetic wound healing	269:290	diabetic wound healing	269:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	5	33	theme	coupling	941:948	arg1	factors					957:963	chemically coupling growth factors	930:963	chemically coupling growth factors	930:963	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	5	34	theme	UV	885:886	arg1	irradiation					888:898	UV irradiation	885:898	UV irradiation	885:898	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	2	35	theme	diabetic	269:276	arg1	healing					284:290	diabetic wound healing	269:290	diabetic wound healing	269:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	4	36	theme	ion	714:716	arg1	crosslinking					718:729	calcium ion crosslinking	706:729	calcium ion crosslinking	706:729	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	0	37	theme	diabetic	83:90	arg1	healing					98:104	diabetic wound healing	83:104	diabetic wound healing	83:104	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	4	38	theme	sulfate	591:597	arg1	biomaterials					625:636	biomaterials	625:636	biomaterials	625:636	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	38	theme	sulfate	591:597	arg1	methacryloyl					599:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	6	39	theme	angiogenic	1066:1075	arg1	patches					1077:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	39	theme	angiogenic	1066:1075	arg1	candidates					1095:1104	ideal candidates	1089:1104	ideal candidates for diabetic wound healing and other tissue engineering applications	1089:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	40	theme	3D-bioprinted	1033:1045	arg1	patches					1077:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	40	theme	3D-bioprinted	1033:1045	arg1	candidates					1095:1104	ideal candidates	1089:1104	ideal candidates for diabetic wound healing and other tissue engineering applications	1089:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	2	41	theme	3D-bioprinted	243:255	arg1	patches					257:263	double-crosslinked angiogenic 3D-bioprinted patches	213:263	double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing	213:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	42	theme	ultraviolet	377:387	arg1	irradiation					394:404	ultraviolet (UV) irradiation	377:404	ultraviolet (UV) irradiation	377:404	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	6	43	theme	double-crosslinked	1047:1064	arg1	patches					1077:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	43	theme	double-crosslinked	1047:1064	arg1	candidates					1095:1104	ideal candidates	1089:1104	ideal candidates for diabetic wound healing and other tissue engineering applications	1089:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	2	44	theme	angiogenic	232:241	arg1	patches					257:263	double-crosslinked angiogenic 3D-bioprinted patches	213:263	double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing	213:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	45	theme	photocovalent	299:311	arg1	crosslinking					313:324	the photocovalent crosslinking	295:324	the photocovalent crosslinking of vascular endothelial growth factor (VEGF)	295:369	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	2	46	theme	double-crosslinked	213:230	arg1	patches					257:263	double-crosslinked angiogenic 3D-bioprinted patches	213:263	double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing	213:290	In this study, we developed double-crosslinked angiogenic 3D-bioprinted patches for diabetic wound healing by the photocovalent crosslinking of vascular endothelial growth factor (VEGF) using ultraviolet (UV) irradiation.					
36894059	6	47	link	double-crosslinked	1047:1064	arg1	patches					1077:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	3D-bioprinted double-crosslinked angiogenic patches	1033:1083	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	6	47	link	double-crosslinked	1047:1064	arg1	candidates					1095:1104	ideal candidates	1089:1104	ideal candidates for diabetic wound healing and other tissue engineering applications	1089:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	5	48	theme	growth	950:955	arg1	factors					957:963	chemically coupling growth factors	930:963	chemically coupling growth factors	930:963	More importantly, acrylylated VEGF could be easily and rapidly photocrosslinked under UV irradiation, which simplified the step of chemically coupling growth factors and prolonged VEGF release time.					
36894059	3	49	dep	different	503:511	arg1	clinical					513:520	clinical	513:520	clinical	513:520	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	3	50	theme	different	503:511	arg1	requirements					522:533	different clinical requirements	503:533	different clinical requirements	503:533	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	1	51	theme	clinical	166:173	arg1	practice					175:182	the clinical practice	162:182	the clinical practice	162:182	Improving chronic wound healing remains a challenge in the clinical practice.					
36894059	6	52	theme	engineering	1150:1160	arg1	applications					1162:1173	other tissue engineering applications	1137:1173	other tissue engineering applications	1137:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36894059	0	53	theme	wound	92:96	arg1	healing					98:104	diabetic wound healing	83:104	diabetic wound healing	83:104	3D-bioprinted double-crosslinked angiogenic alginate/chondroitin sulfate patch for diabetic wound healing.					
36894059	4	54	theme	alginate	566:573	arg1	biomaterials					625:636	biomaterials	625:636	biomaterials	625:636	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	4	54	theme	alginate	566:573	arg1	methacryloyl					599:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl	536:610	The biological polysaccharide alginate and chondroitin sulfate methacryloyl were used as biomaterials to construct the biological patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking, thereby improving its mechanical properties.					
36894059	3	55	theme	printing	410:417	arg1	technology					419:428	3D printing technology	407:428	3D printing technology	407:428	3D printing technology can precisely customize the structure and composition of patches to meet different clinical requirements.					
36894059	6	56	theme	tissue	1143:1148	arg1	applications					1162:1173	other tissue engineering applications	1137:1173	other tissue engineering applications	1137:1173	These characteristics suggest that 3D-bioprinted double-crosslinked angiogenic patches are ideal candidates for diabetic wound healing and other tissue engineering applications.					
36878693	3	0	theme	representative	659:672	arg1	methods					685:691	four representative extraction methods	654:691	four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader)	654:731	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	0	theme	representative	659:672	arg1	Wise					704:707	Wise	704:707	Wise	704:707	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	0	theme	representative	659:672	arg1	Jayme					694:698	Jayme	694:698	Jayme	694:698	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	0	1	theme	Studies	164:170	arg1	Purity					16:21	Chemical Purity	7:21	Chemical Purity	7:21	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	0	1	theme	Studies	164:170	arg1	Composition					43:53	Oxygen Isotopic Composition	27:53	Oxygen Isotopic Composition	27:53	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	3	2	from	species	840:846	arg1	sugars					786:791	the hemicellulose-derived non-glucose sugars	748:791	the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species	748:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	2	from	species	840:846	arg1	products					812:819	the α-cellulose products	796:819	the α-cellulose products from 40 land grass species	796:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	1	3	theme	climate	248:254	arg1	studies					301:307	climate, environmental, physiological, and metabolic studies	248:307	climate, environmental, physiological, and metabolic studies	248:307	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	6	4	theme	highest	1170:1176	arg1	α-cellulose					1185:1195	the highest purity α-cellulose	1166:1195	the highest purity α-cellulose	1166:1195	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	6	5	theme	second-lowest	1249:1261	arg1	presence					1263:1270	the second-lowest presence	1245:1270	the second-lowest presence of non-glucose sugars	1245:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	8	6	theme	hexoses	1873:1879	arg1	precursor					1847:1855	the common precursor	1836:1855	the common precursor of pentoses and hexoses in cellulose	1836:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	6	theme	hexoses	1873:1879	arg1	sucrose					1827:1833	sucrose	1827:1833	sucrose	1827:1833	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	1	7	theme	18O/16O	177:183	arg1	ratio					185:189	The 18O/16O ratio	173:189	The 18O/16O ratio of α-cellulose in land plants	173:219	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	6	8	theme	Zhou	1145:1148	arg1	method					1150:1155	the Zhou method	1141:1155	the Zhou method	1141:1155	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	6	9	theme	lignin	1234:1239	arg1	presence					1222:1229	the minimal presence	1210:1229	the minimal presence of lignin and the second-lowest presence of non-glucose sugars	1210:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	0	10	theme	Metabolic	135:143	arg1	Studies					164:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	1	11	from	ratio	185:189	arg1	plants					214:219	land plants	209:219	land plants	209:219	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	3	12	theme	land	829:832	arg1	species					840:846	40 land grass species	826:846	40 land grass species	826:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	7	13	theme	glucosyl	1361:1368	arg1	units					1370:1374	the α-cellulose glucosyl units	1345:1374	the α-cellulose glucosyl units	1345:1374	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	3	14	theme	non-glucose	774:784	arg1	sugars					786:791	the hemicellulose-derived non-glucose sugars	748:791	the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species	748:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	5	15	theme	isotope	1048:1054	arg1	analysis					1056:1063	the bulk isotope analysis	1039:1063	the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products	1039:1115	These results were then compared with the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products.					
36878693	3	16	theme	hydrolysates	601:612	arg1	quality					590:596	the quality	586:596	the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS)	586:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	17	theme	gas	854:856	arg1	GC/MS					892:896	GC/MS	892:896	GC/MS	892:896	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	17	theme	gas	854:856	arg1	spectrometry					878:889	gas chromatography-mass spectrometry	854:889	gas chromatography-mass spectrometry (GC/MS)	854:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	18	theme	α-cellulose	800:810	arg1	products					812:819	the α-cellulose products	796:819	the α-cellulose products from 40 land grass species	796:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	0	19	theme	Extractable	70:80	arg1	Studies					164:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	7	20	dep	mUr	1412:1414	arg1	average					1417:1423	average	1417:1423	average	1417:1423	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	7	20	dep	mUr	1412:1414	arg1	mUr					1430:1432	1.9 mUr	1426:1432	1.9 mUr	1426:1432	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	4	21	theme	compound-specific	921:937	arg1	analysis					947:954	compound-specific isotope analysis	921:954	compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS	921:998	Second, we performed compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS.					
36878693	8	22	dep	18O	1734:1736	arg1	compared					1739:1746	compared	1739:1746	compared to hexoses	1739:1757	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	0	23	theme	Higher	87:92	arg1	Plants					94:99	Higher Plants	87:99	Higher Plants	87:99	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	5	24	theme	α-cellulose	1096:1106	arg1	products					1108:1115	the α-cellulose products	1092:1115	the α-cellulose products	1092:1115	These results were then compared with the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products.					
36878693	8	25	theme	O-2-O-5	1809:1815	arg1	moiety					1817:1822	the relatively 18O-enriched O-2-O-5 moiety	1781:1822	the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose	1781:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	2	26	from	obtainable	437:446	arg1	presence					373:380	the presence	369:380	the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods	369:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	2	27	theme	product	429:435	arg1	obtainable					437:446	the α-cellulose product obtainable	413:446	the α-cellulose product obtainable with current extraction methods	413:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	8	28	theme	isotopic	1516:1523	arg1	bias					1525:1528	The positive isotopic bias	1503:1528	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units	1503:1591	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	3	29	link	hemicellulose-derived	752:772	arg1	sugars					786:791	the hemicellulose-derived non-glucose sugars	748:791	the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species	748:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	8	30	from	precursor	1847:1855	arg1	cellulose					1884:1892	cellulose	1884:1892	cellulose	1884:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	2	31	theme	impurities	399:408	arg1	presence					373:380	the presence	369:380	the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods	369:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	0	32	theme	Chemical	7:14	arg1	Purity					16:21	Chemical Purity	7:21	Chemical Purity	7:21	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	3	33	dep	methods	685:691	arg1	methods					685:691	four representative extraction methods	654:691	four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader)	654:731	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	33	dep	methods	685:691	arg1	Wise					704:707	Wise	704:707	Wise	704:707	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	33	dep	methods	685:691	arg1	Jayme					694:698	Jayme	694:698	Jayme	694:698	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	2	34	theme	extraction	461:470	arg1	methods					472:478	current extraction methods	453:478	current extraction methods	453:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	3	35	theme	products	630:637	arg1	hydrolysates					601:612	hydrolysates	601:612	hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS)	601:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	36	dep	Jayme	694:698	arg1	Zhou					719:722	Zhou	719:722	Zhou	719:722	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	36	dep	Jayme	694:698	arg1	Brendel					710:716	Brendel	710:716	Brendel	710:716	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	36	dep	Jayme	694:698	arg1	Loader					725:730	Loader	725:730	Jayme and Wise; Brendel; Zhou; Loader	694:730	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	8	37	from	hexoses	1873:1879	arg1	cellulose					1884:1892	cellulose	1884:1892	cellulose	1884:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	0	38	theme	Isotopic	34:41	arg1	Composition					43:53	Oxygen Isotopic Composition	27:53	Oxygen Isotopic Composition	27:53	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	1	39	theme	metabolic	291:299	arg1	studies					301:307	climate, environmental, physiological, and metabolic studies	248:307	climate, environmental, physiological, and metabolic studies	248:307	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	8	40	theme	pentoses	1860:1867	arg1	precursor					1847:1855	the common precursor	1836:1855	the common precursor of pentoses and hexoses in cellulose	1836:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	40	theme	pentoses	1860:1867	arg1	sucrose					1827:1833	sucrose	1827:1833	sucrose	1827:1833	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	41	from	pentoses	1860:1867	arg1	cellulose					1884:1892	cellulose	1884:1892	cellulose	1884:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	2	42	theme	Reliable	310:317	arg1	application					319:329	Reliable application	310:329	Reliable application of such a ratio	310:345	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	1	43	theme	land	209:212	arg1	plants					214:219	land plants	209:219	land plants	209:219	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	8	44	theme	glucosyl	1578:1585	arg1	units					1587:1591	the glucosyl units	1574:1591	the glucosyl units	1574:1591	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	7	45	theme	relative	1465:1472	arg1	manner					1458:1463	a species-dependent manner	1438:1463	a species-dependent manner relative to the α-cellulose products	1438:1500	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	2	46	from	impurities	399:408	arg1	obtainable					437:446	the α-cellulose product obtainable	413:446	the α-cellulose product obtainable with current extraction methods	413:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	0	47	from	Implications	109:120	arg1	Extractable					70:80	Extractable	70:80	Extractable	70:80	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	8	48	theme	common	1840:1845	arg1	precursor					1847:1855	the common precursor	1836:1855	the common precursor of pentoses and hexoses in cellulose	1836:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	48	theme	common	1840:1845	arg1	sucrose					1827:1833	sucrose	1827:1833	sucrose	1827:1833	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	49	theme	hemicellulose	1652:1664	arg1	contamination					1666:1678	hemicellulose contamination	1652:1678	hemicellulose contamination	1652:1678	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	7	50	theme	species-dependent	1440:1456	arg1	manner					1458:1463	a species-dependent manner	1438:1463	a species-dependent manner relative to the α-cellulose products	1438:1500	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	2	51	from	that	543:546	arg1	different					528:536	different	528:536	different	528:536	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	2	51	from	that	543:546	arg1	impurities					488:497	the impurities	484:497	the impurities	484:497	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	3	52	theme	extraction	674:683	arg1	methods					685:691	four representative extraction methods	654:691	four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader)	654:731	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	52	theme	extraction	674:683	arg1	Wise					704:707	Wise	704:707	Wise	704:707	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	52	theme	extraction	674:683	arg1	Jayme					694:698	Jayme	694:698	Jayme	694:698	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	6	53	theme	non-glucose	1275:1285	arg1	sugars					1287:1292	non-glucose sugars	1275:1292	non-glucose sugars	1275:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	6	54	theme	purity	1178:1183	arg1	α-cellulose					1185:1195	the highest purity α-cellulose	1166:1195	the highest purity α-cellulose	1166:1195	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	6	55	theme	presence	1263:1270	arg1	presence					1222:1229	the minimal presence	1210:1229	the minimal presence of lignin and the second-lowest presence of non-glucose sugars	1210:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	8	56	theme	α-cellulose	1687:1697	arg1	product					1699:1705	the α-cellulose product	1683:1705	the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis	1683:1956	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	1	57	theme	α-cellulose	194:204	arg1	ratio					185:189	The 18O/16O ratio	173:189	The 18O/16O ratio of α-cellulose in land plants	173:219	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	6	58	theme	minimal	1214:1220	arg1	presence					1222:1229	the minimal presence	1210:1229	the minimal presence of lignin and the second-lowest presence of non-glucose sugars	1210:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	0	59	theme	Physiological	150:162	arg1	Studies					164:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies	58:170	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	5	60	theme	bulk	1043:1046	arg1	analysis					1056:1063	the bulk isotope analysis	1039:1063	the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products	1039:1115	These results were then compared with the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products.					
36878693	3	61	theme	grass	834:838	arg1	species					840:846	40 land grass species	826:846	40 land grass species	826:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	0	62	from	Plants	94:99	arg1	Extractable					70:80	Extractable	70:80	Extractable	70:80	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	7	63	theme	units	1370:1374	arg1	O-2-O-6					1334:1340	the O-2-O-6	1330:1340	the O-2-O-6 of the α-cellulose glucosyl units	1330:1374	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	2	64	with	obtainable	437:446	arg1	methods					472:478	current extraction methods	453:478	current extraction methods	453:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	7	65	theme	α-cellulose	1349:1359	arg1	units					1370:1374	the α-cellulose glucosyl units	1345:1374	the α-cellulose glucosyl units	1345:1374	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	3	66	theme	hemicellulose-derived	752:772	arg1	sugars					786:791	the hemicellulose-derived non-glucose sugars	748:791	the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species	748:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	8	67	theme	incomplete	1935:1944	arg1	hydrolysis					1947:1956	the (incomplete) hydrolysis	1930:1956	the (incomplete) hydrolysis	1930:1956	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	3	68	theme	chromatography-mass	858:876	arg1	GC/MS					892:896	GC/MS	892:896	GC/MS	892:896	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	68	theme	chromatography-mass	858:876	arg1	spectrometry					878:889	gas chromatography-mass spectrometry	854:889	gas chromatography-mass spectrometry (GC/MS)	854:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	4	69	theme	hydrolysates	963:974	arg1	analysis					947:954	compound-specific isotope analysis	921:954	compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS	921:998	Second, we performed compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS.					
36878693	8	70	theme	positive	1507:1514	arg1	bias					1525:1528	The positive isotopic bias	1503:1528	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units	1503:1591	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	5	71	theme	products	1108:1115	arg1	EA/Pyrolysis/IRMS					1071:1087	EA/Pyrolysis/IRMS	1071:1087	EA/Pyrolysis/IRMS of the α-cellulose products	1071:1115	These results were then compared with the bulk isotope analysis using EA/Pyrolysis/IRMS of the α-cellulose products.					
36878693	8	72	theme	18O-enriched	1796:1807	arg1	moiety					1817:1822	the relatively 18O-enriched O-2-O-5 moiety	1781:1822	the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose	1781:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	4	73	theme	isotope	939:945	arg1	analysis					947:954	compound-specific isotope analysis	921:954	compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS	921:998	Second, we performed compound-specific isotope analysis of the hydrolysates using GC/Pyrolysis/IRMS.					
36878693	2	74	theme	α-cellulose	417:427	arg1	obtainable					437:446	the α-cellulose product obtainable	413:446	the α-cellulose product obtainable with current extraction methods	413:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	8	75	dep	product	1699:1705	arg1	enriched					1722:1729	enriched	1722:1729	are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis	1707:1956	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	1	76	theme	environmental	257:269	arg1	studies					301:307	climate, environmental, physiological, and metabolic studies	248:307	climate, environmental, physiological, and metabolic studies	248:307	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	8	77	theme	sucrose	1827:1833	arg1	moiety					1817:1822	the relatively 18O-enriched O-2-O-5 moiety	1781:1822	the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose	1781:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	78	theme	α-cellulose	1543:1553	arg1	product					1555:1561	the α-cellulose product	1539:1561	the α-cellulose product instead of the glucosyl units	1539:1591	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	3	79	theme	α-cellulose	618:628	arg1	products					630:637	"α-cellulose products	617:637	"α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS)	617:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	2	80	theme	hemicellulose	385:397	arg1	impurities					399:408	hemicellulose impurities	385:408	hemicellulose impurities in the α-cellulose product obtainable with current extraction methods	385:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	0	81	theme	Oxygen	27:32	arg1	Composition					43:53	Oxygen Isotopic Composition	27:53	Oxygen Isotopic Composition	27:53	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	1	82	theme	physiological	272:284	arg1	studies					301:307	climate, environmental, physiological, and metabolic studies	248:307	climate, environmental, physiological, and metabolic studies	248:307	The 18O/16O ratio of α-cellulose in land plants has proved of interest for climate, environmental, physiological, and metabolic studies.					
36878693	7	83	theme	Isotopic	1295:1302	arg1	analysis					1304:1311	Isotopic analysis	1295:1311	Isotopic analysis	1295:1311	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	2	84	theme	current	453:459	arg1	methods					472:478	current extraction methods	453:478	current extraction methods	453:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	6	85	theme	sugars	1287:1292	arg1	presence					1263:1270	the second-lowest presence	1245:1270	the second-lowest presence of non-glucose sugars	1245:1292	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	6	85	theme	sugars	1287:1292	arg1	lignin					1234:1239	lignin	1234:1239	lignin	1234:1239	We found that overall, the Zhou method afforded the highest purity α-cellulose as judged by the minimal presence of lignin and the second-lowest presence of non-glucose sugars.					
36878693	0	86	dep	Purity	16:21	arg1	the					3:5	the	3:5	the	3:5	On the Chemical Purity and Oxygen Isotopic Composition of α-Cellulose Extractable from Higher Plants and the Implications for Climate, Metabolic, and Physiological Studies.					
36878693	8	87	theme	units	1587:1591	arg1	product					1555:1561	the α-cellulose product	1539:1561	the α-cellulose product instead of the glucosyl units	1539:1591	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	3	88	from	sugars	786:791	arg1	species					840:846	40 land grass species	826:846	40 land grass species	826:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	88	from	sugars	786:791	arg1	products					812:819	the α-cellulose products	796:819	the α-cellulose products from 40 land grass species	796:846	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	7	89	theme	α-cellulose	1481:1491	arg1	products					1493:1500	the α-cellulose products	1477:1500	the α-cellulose products	1477:1500	Isotopic analysis then showed that the O-2-O-6 of the α-cellulose glucosyl units were all depleted in 18O by 0.0-4.3 mUr (average, 1.9 mUr) in a species-dependent manner relative to the α-cellulose products.					
36878693	2	90	from	presence	373:380	arg1	obtainable					437:446	the α-cellulose product obtainable	413:446	the α-cellulose product obtainable with current extraction methods	413:478	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	8	91	from	cellulose	1884:1892	arg1	precursor					1847:1855	the common precursor	1836:1855	the common precursor of pentoses and hexoses in cellulose	1836:1892	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	8	91	from	cellulose	1884:1892	arg1	sucrose					1827:1833	sucrose	1827:1833	sucrose	1827:1833	The positive isotopic bias of using the α-cellulose product instead of the glucosyl units stems mainly from the fact that the pentoses that dominate hemicellulose contamination in the α-cellulose product are relatively enriched in 18O (compared to hexoses) as they inherit only the relatively 18O-enriched O-2-O-5 moiety of sucrose, the common precursor of pentoses and hexoses in cellulose, and are further enriched in 18O by the (incomplete) hydrolysis.					
36878693	2	92	theme	ratio	341:345	arg1	application					319:329	Reliable application	310:329	Reliable application of such a ratio	310:345	Reliable application of such a ratio may be compromised by the presence of hemicellulose impurities in the α-cellulose product obtainable with current extraction methods, as the impurities are known to be isotopically different from that of the α-cellulose.					
36878693	3	93	dep	products	630:637	arg1	obtained					640:647	obtained	640:647	" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader)	638:731	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
36878693	3	93	dep	products	630:637	arg1	quantified					737:746	quantified	737:746	quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS)	737:897	We first compared the quality of hydrolysates of "α-cellulose products" obtained with four representative extraction methods (Jayme and Wise; Brendel; Zhou; Loader) and quantified the hemicellulose-derived non-glucose sugars in the α-cellulose products from 40 land grass species using gas chromatography-mass spectrometry (GC/MS).					
35963358	1	0	theme	composite	307:315	arg1	films					317:321	composite films	307:321	composite films	307:321	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	2	1	theme	CSG-RA/Cur73	545:556	arg1	films					564:568	CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films	511:568	films	564:568	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	4	2	from	fourier	794:800	arg1	results					781:787	The results	777:787	The results from fourier transform infrared spectroscopy and scanning electron microscopy	777:865	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	1	3	theme	Rubus	165:169	arg1	L					178:178	Rubus idaeus L	165:178	Rubus idaeus L. (Rosaceae)	165:190	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	3	theme	Rubus	165:169	arg1	Rosaceae					182:189	Rosaceae	182:189	Rosaceae	182:189	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	4	theme	water	1318:1322	arg1	vapor					1324:1328	water vapor	1318:1328	water vapor	1318:1328	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	0	5	theme	curcumin	85:92	arg1	evaluation					45:54	Preparation, physicochemical and application evaluation	0:54	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin	0:92	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	1	6	theme	films	317:321	arg1	properties					293:302	the physicochemical properties	273:302	the physicochemical properties of composite films	273:321	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	5	7	theme	tensile	1013:1019	arg1	strength					1021:1028	the tensile strength	1009:1028	the tensile strength	1009:1028	The hydrophobic Cur increased the tensile strength from 6 Mpa (CSG) to 14 Mpa (CSG-Cur), but reduced the elongation at break from 55 % (CSG) to 40 % (CSG-Cur).					
35963358	7	8	theme	pH-sensitive	1425:1436	arg1	film					1456:1459	a pH-sensitive indicator/packing film	1423:1459	a pH-sensitive indicator/packing film	1423:1459	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	4	9	theme	scanning	838:845	arg1	microscopy					856:865	scanning electron microscopy	838:865	scanning electron microscopy	838:865	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	0	10	theme	chitosan/starch/gelatin	103:125	arg1	film					127:130	chitosan/starch/gelatin film	103:130	chitosan/starch/gelatin film	103:130	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	3	11	dep	ABTS	707:710	arg1	2,2'-azino-bis-					713:727	2,2'-azino-bis-	713:727	2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)	713:767	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	3	11	dep	ABTS	707:710	arg1	acid					763:766	3-ethylbenzothiazoline-6-sulfonic acid	729:766	3-ethylbenzothiazoline-6-sulfonic acid	729:766	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	6	12	theme	color	1145:1149	arg1	films					1151:1155	These color films	1139:1155	These color films	1139:1155	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	5	13	theme	hydrophobic	983:993	arg1	Cur					995:997	The hydrophobic Cur	979:997	The hydrophobic Cur	979:997	The hydrophobic Cur increased the tensile strength from 6 Mpa (CSG) to 14 Mpa (CSG-Cur), but reduced the elongation at break from 55 % (CSG) to 40 % (CSG-Cur).					
35963358	6	14	theme	content	1306:1312	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	5	15	dep	increased	999:1007	arg1	CSG					1042:1044	CSG	1042:1044	CSG	1042:1044	The hydrophobic Cur increased the tensile strength from 6 Mpa (CSG) to 14 Mpa (CSG-Cur), but reduced the elongation at break from 55 % (CSG) to 40 % (CSG-Cur).					
35963358	2	16	theme	composite	479:487	arg1	CSG					495:497	CSG	495:497	CSG	495:497	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	2	16	theme	composite	479:487	arg1	film					489:492	chitosan/starch/gelatin composite film	455:492	chitosan/starch/gelatin composite film (CSG)	455:498	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	5	17	dep	reduced	1072:1078	arg1	CSG					1115:1117	CSG	1115:1117	CSG	1115:1117	The hydrophobic Cur increased the tensile strength from 6 Mpa (CSG) to 14 Mpa (CSG-Cur), but reduced the elongation at break from 55 % (CSG) to 40 % (CSG-Cur).					
35963358	4	18	theme	electron	847:854	arg1	microscopy					856:865	scanning electron microscopy	838:865	scanning electron microscopy	838:865	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	2	19	theme	chitosan/starch/gelatin	455:477	arg1	CSG					495:497	CSG	495:497	CSG	495:497	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	2	19	theme	chitosan/starch/gelatin	455:477	arg1	film					489:492	chitosan/starch/gelatin composite film	455:492	chitosan/starch/gelatin composite film (CSG)	455:498	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	3	20	theme	higher	671:676	arg1	activities					690:699	higher antioxidant activities	671:699	higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay	671:774	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	2	21	theme	solution	573:580	arg1	method					590:595	solution casting method	573:595	solution casting method	573:595	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	2	22	theme	casting	582:588	arg1	method					590:595	solution casting method	573:595	solution casting method	573:595	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	4	23	theme	CSG	917:919	arg1	matrix					921:926	the CSG matrix	913:926	the CSG matrix	913:926	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	1	24	theme	bioactive	331:339	arg1	components					349:358	bioactive pigment components	331:358	bioactive pigment components	331:358	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	24	theme	bioactive	331:339	arg1	properties					391:400	pH-responsive properties	377:400	pH-responsive properties	377:400	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	25	theme	moisture	1297:1304	arg1	content					1306:1312	moisture content	1297:1312	moisture content	1297:1312	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	1	26	theme	pigment	341:347	arg1	components					349:358	bioactive pigment components	331:358	bioactive pigment components	331:358	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	26	theme	pigment	341:347	arg1	properties					391:400	pH-responsive properties	377:400	pH-responsive properties	377:400	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	27	dep	Rubus	165:169	arg1	idaeus					171:176	idaeus	171:176	idaeus	171:176	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	28	contain	had	1157:1159	arg2	effect					1182:1187	a good fresh-keeping effect	1161:1187	a good fresh-keeping effect	1161:1187	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	28	contain	had	1157:1159	arg1	films					1151:1155	These color films	1139:1155	These color films	1139:1155	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	0	29	theme	Preparation	0:10	arg1	evaluation					45:54	Preparation, physicochemical and application evaluation	0:54	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin	0:92	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	2	30	theme	color	558:562	arg1	films					564:568	CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films	511:568	films	564:568	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	4	31	theme	films	972:976	arg1	structure					945:953	the structure	941:953	the structure of the composite films	941:976	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	5	32	from	break	1098:1102	arg1	elongation					1084:1093	the elongation	1080:1093	the elongation at break	1080:1102	The hydrophobic Cur increased the tensile strength from 6 Mpa (CSG) to 14 Mpa (CSG-Cur), but reduced the elongation at break from 55 % (CSG) to 40 % (CSG-Cur).					
35963358	4	33	dep	transform	802:810	arg1	infrared					812:819	infrared	812:819	transform infrared spectroscopy and scanning electron microscopy	802:865	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	3	34	theme	ABTS	707:710	arg1	assay					770:774	ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay	707:774	ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay	707:774	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	0	35	theme	physicochemical	13:27	arg1	evaluation					45:54	Preparation, physicochemical and application evaluation	0:54	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin	0:92	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	3	36	theme	antioxidant	678:688	arg1	activities					690:699	higher antioxidant activities	671:699	higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay	671:774	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	6	37	theme	solubility	1274:1283	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	38	from	monitoring	1203:1212	arg1	particular					1218:1227	particular	1218:1227	particular	1218:1227	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	1	39	from	longa	224:228	arg1	L					178:178	Rubus idaeus L	165:178	Rubus idaeus L. (Rosaceae)	165:190	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	39	from	longa	224:228	arg1	Rosaceae					182:189	Rosaceae	182:189	Rosaceae	182:189	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	39	from	longa	224:228	arg1	curcumin					196:203	curcumin	196:203	curcumin (Cur) from Curcuma longa	196:228	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	39	from	longa	224:228	arg1	Cur					206:208	Cur	206:208	Cur	206:208	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	7	40	contain	had	1395:1397	arg1	films					1389:1393	binary pigment films	1374:1393	binary pigment films	1374:1393	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	7	40	contain	had	1395:1397	arg2	potential					1403:1411	the potential to become a pH-sensitive indicator/packing film	1399:1459	the potential to become a pH-sensitive indicator/packing film	1399:1459	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	0	41	theme	application	33:43	arg1	evaluation					45:54	Preparation, physicochemical and application evaluation	0:54	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin	0:92	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	6	42	theme	water	1268:1272	arg1	solubility					1274:1283	water solubility	1268:1283	water solubility	1268:1283	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	43	theme	freshness	1193:1201	arg1	CSG-RA/Cur73					1230:1241	CSG-RA/Cur73	1230:1241	CSG-RA/Cur73	1230:1241	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	43	theme	freshness	1193:1201	arg1	monitoring					1203:1212	freshness monitoring	1193:1212	freshness monitoring	1193:1212	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	44	theme	thickness	1286:1294	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	1	45	from	curcumin	196:203	arg1	RA					156:157	RA	156:157	RA	156:157	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	45	from	curcumin	196:203	arg1	anthocyanin					143:153	Raspberry anthocyanin	133:153	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L.	133:231	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	3	46	theme	pH	649:650	arg1	conditions					652:661	different pH conditions	639:661	different pH conditions	639:661	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	0	47	theme	raspberry	59:67	arg1	anthocyanin					69:79	raspberry anthocyanin	59:79	raspberry anthocyanin	59:79	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	3	48	theme	3-ethylbenzothiazoline-6-sulfonic	729:761	arg1	2,2'-azino-bis-					713:727	2,2'-azino-bis-	713:727	2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)	713:767	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	3	48	theme	3-ethylbenzothiazoline-6-sulfonic	729:761	arg1	acid					763:766	3-ethylbenzothiazoline-6-sulfonic acid	729:766	3-ethylbenzothiazoline-6-sulfonic acid	729:766	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	2	49	theme	CSG-Cur	519:525	arg1	films					564:568	CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films	511:568	films	564:568	In this study, RA and Cur were added to chitosan/starch/gelatin composite film (CSG) to prepare CSG-RA, CSG-Cur, CSG-RA/Cur82 and CSG-RA/Cur73 color films by solution casting method.					
35963358	7	50	theme	pigment	1381:1387	arg1	films					1389:1393	binary pigment films	1374:1393	binary pigment films	1374:1393	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	1	51	dep	L	178:178	arg1	L					230:230	L	230:230	L	230:230	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	52	dep	improve	265:271	arg1	Zingiberaceae					234:246	Zingiberaceae	234:246	Zingiberaceae	234:246	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	53	theme	Raspberry	133:141	arg1	RA					156:157	RA	156:157	RA	156:157	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	53	theme	Raspberry	133:141	arg1	anthocyanin					143:153	Raspberry anthocyanin	133:153	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L.	133:231	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	4	54	theme	composite	962:970	arg1	films					972:976	the composite films	958:976	the composite films	958:976	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	1	55	theme	physicochemical	277:291	arg1	properties					293:302	the physicochemical properties	273:302	the physicochemical properties of composite films	273:321	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	56	theme	fresh-keeping	1168:1180	arg1	effect					1182:1187	a good fresh-keeping effect	1161:1187	a good fresh-keeping effect	1161:1187	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	7	57	theme	binary	1374:1379	arg1	films					1389:1393	binary pigment films	1374:1393	binary pigment films	1374:1393	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	6	58	theme	other	1352:1356	arg1	films					1358:1362	the other films	1348:1362	the other films	1348:1362	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	59	theme	good	1163:1166	arg1	effect					1182:1187	a good fresh-keeping effect	1161:1187	a good fresh-keeping effect	1161:1187	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	1	60	theme	pH-responsive	377:389	arg1	components					349:358	bioactive pigment components	331:358	bioactive pigment components	331:358	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	60	theme	pH-responsive	377:389	arg1	properties					391:400	pH-responsive properties	377:400	pH-responsive properties	377:400	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	61	contain	had	1244:1246	arg1	CSG-RA/Cur73					1230:1241	CSG-RA/Cur73	1230:1241	CSG-RA/Cur73	1230:1241	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	61	contain	had	1244:1246	arg1	monitoring					1203:1212	freshness monitoring	1193:1212	freshness monitoring	1193:1212	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	61	contain	had	1244:1246	arg2	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	7	62	theme	indicator/packing	1438:1454	arg1	film					1456:1459	a pH-sensitive indicator/packing film	1423:1459	a pH-sensitive indicator/packing film	1423:1459	Briefly, binary pigment films had the potential to become a pH-sensitive indicator/packing film.					
35963358	3	63	theme	color	602:606	arg1	films					608:612	The color films	598:612	The color films	598:612	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	3	64	contain	had	667:669	arg1	films					608:612	The color films	598:612	The color films	598:612	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	3	64	contain	had	667:669	arg2	activities					690:699	higher antioxidant activities	671:699	higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay	671:774	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	6	65	theme	better	1252:1257	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	6	66	theme	opacity	1259:1265	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	0	67	theme	anthocyanin	69:79	arg1	evaluation					45:54	Preparation, physicochemical and application evaluation	0:54	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin	0:92	Preparation, physicochemical and application evaluation of raspberry anthocyanin and curcumin based on chitosan/starch/gelatin film.					
35963358	3	68	theme	different	639:647	arg1	conditions					652:661	different pH conditions	639:661	different pH conditions	639:661	The color films could change color under different pH conditions and had higher antioxidant activities using ABTS (2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) assay.					
35963358	4	69	dep	fourier	794:800	arg1	transform					802:810	transform	802:810	transform infrared spectroscopy and scanning electron microscopy	802:865	The results from fourier transform infrared spectroscopy and scanning electron microscopy showed that RA and Cur were well dispersed in the CSG matrix and improved the structure of the composite films.					
35963358	1	70	from	L	178:178	arg1	RA					156:157	RA	156:157	RA	156:157	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	1	70	from	L	178:178	arg1	anthocyanin					143:153	Raspberry anthocyanin	133:153	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L.	133:231	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35963358	6	71	theme	vapor	1324:1328	arg1	permeability					1330:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	the better opacity, water solubility, thickness, moisture content and water vapor permeability	1248:1341	These color films had a good fresh-keeping effect and freshness monitoring, in particular, CSG-RA/Cur73, had the better opacity, water solubility, thickness, moisture content and water vapor permeability than the other films.					
35963358	1	72	theme	Curcuma	216:222	arg1	longa					224:228	Curcuma longa	216:228	Curcuma longa	216:228	Raspberry anthocyanin (RA) from Rubus idaeus L. (Rosaceae) and curcumin (Cur) from Curcuma longa L. (Zingiberaceae) can effectively improve the physicochemical properties of composite films, and as bioactive pigment components, they can impart pH-responsive properties to the film.					
35508170	4	0	theme	wall	501:504	arg1	volume					482:487	the volume	478:487	the volume of the cell wall	478:504	Although their biochemical composition is well known, how the different components organize in the volume of the cell wall and interact with each other is not well understood and yet is key to the wall's mechanical properties.					
35508170	7	1	theme	inner	1039:1043	arg1	surface					1045:1051	the inner surface	1035:1051	the inner surface of the cell wall	1035:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	8	2	theme	cell	1231:1234	arg1	wall					1236:1239	the cell wall	1227:1239	the cell wall	1227:1239	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	5	3	theme	cepa	705:708	arg1	bulbs					711:715	onion (Allium cepa) bulbs	691:715	onion (Allium cepa) bulbs	691:715	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	4	from	walls	682:686	arg1	state					734:738	a near-native state	720:738	a near-native state	720:738	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	0	5	theme	cellulose	73:81	arg1	fibers					83:88	bimodally oriented cellulose fibers	54:88	bimodally oriented cellulose fibers	54:88	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	6	6	theme	high-resolution	850:864	arg1	visualization					866:878	the high-resolution visualization	846:878	the high-resolution visualization of cellulose fibers in situ	846:906	This allowed the high-resolution visualization of cellulose fibers in situ.					
35508170	10	7	theme	proximal	1665:1672	arg1	meshing					1657:1663	the surrounding HG-rich meshing	1633:1663	the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall	1633:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	8	from	and +45°	1578:1585	arg1	layers					1543:1548	successive layers	1532:1548	successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis	1532:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	8	from	and +45°	1578:1585	arg1	fibers					1563:1568	cellulose fibers	1553:1568	cellulose fibers at -45° and +45° relative to the cell's long axis	1553:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	0	9	theme	reticulated	94:104	arg1	networks					123:130	reticulated homogalacturonan networks	94:130	reticulated homogalacturonan networks	94:130	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	10	10	theme	surrounding	1637:1647	arg1	meshing					1657:1663	the surrounding HG-rich meshing	1633:1663	the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall	1633:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	7	11	dep	matrix	981:986	arg1	we					988:989	we	988:989	we	988:989	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	8	12	from	depths	1136:1141	arg1	wall					1155:1158	the cell wall	1146:1158	the cell wall	1146:1158	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	5	13	theme	plant	651:655	arg1	wall					662:665	the plant cell wall	647:665	the plant cell wall	647:665	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	7	14	theme	cell	1060:1063	arg1	wall					1065:1068	the cell wall	1056:1068	the cell wall	1056:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	5	15	theme	cryo-electron	797:809	arg1	tomography					811:820	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	tomography	811:820	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	16	theme	Allium	698:703	arg1	bulbs					711:715	onion (Allium cepa) bulbs	691:715	onion (Allium cepa) bulbs	691:715	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	10	17	theme	fibers	1563:1568	arg1	layers					1543:1548	successive layers	1532:1548	successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis	1532:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	18	theme	following	1433:1441	arg1	model					1443:1447	the following model	1429:1447	the following model for the construction of the abaxial epidermal primary cell wall	1429:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	1	19	theme	cell	170:173	arg1	wall					175:178	their cell wall	164:178	their cell wall	164:178	One hallmark of plant cells is their cell wall.					
35508170	0	20	theme	homogalacturonan	106:121	arg1	networks					123:130	reticulated homogalacturonan networks	94:130	reticulated homogalacturonan networks	94:130	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	4	21	theme	cell	496:499	arg1	wall					501:504	the cell wall	492:504	the cell wall	492:504	Although their biochemical composition is well known, how the different components organize in the volume of the cell wall and interact with each other is not well understood and yet is key to the wall's mechanical properties.					
35508170	5	22	theme	near-native	722:732	arg1	state					734:738	a near-native state	720:738	a near-native state	720:738	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	10	23	from	layers	1543:1548	arg1	and +45°					1578:1585	-45° and +45°	1573:1585	-45° and +45° relative to the cell's long axis	1573:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	5	24	theme	beam	761:764	arg1	milling					784:790	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	milling	784:790	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	24	theme	beam	761:764	arg1	cryo-ET					823:829	cryo-ET	823:829	cryo-ET	823:829	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	10	25	theme	successive	1532:1541	arg1	layers					1543:1548	successive layers	1532:1548	successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis	1532:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	5	26	theme	ion	757:759	arg1	milling					784:790	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	milling	784:790	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	26	theme	ion	757:759	arg1	cryo-ET					823:829	cryo-ET	823:829	cryo-ET	823:829	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	6	27	from	visualization	866:878	arg1	situ					903:906	situ	903:906	situ	903:906	This allowed the high-resolution visualization of cellulose fibers in situ.					
35508170	10	28	theme	epidermal	1485:1493	arg1	wall					1508:1511	the abaxial epidermal primary cell wall	1473:1511	the abaxial epidermal primary cell wall	1473:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	2	29	theme	properties	320:329	arg1	dynamics					278:285	the dynamics	274:285	the dynamics of their mechanical and chemical properties	274:329	They protect cells against the environment and high turgor and mediate morphogenesis through the dynamics of their mechanical and chemical properties.					
35508170	10	30	theme	abaxial	1477:1483	arg1	wall					1508:1511	the abaxial epidermal primary cell wall	1473:1511	the abaxial epidermal primary cell wall	1473:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	0	31	theme	Cryo-electron	0:12	arg1	tomography					14:23	Cryo-electron tomography	0:23	Cryo-electron tomography of the onion cell wall	0:46	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	10	32	theme	cell	1503:1506	arg1	wall					1508:1511	the abaxial epidermal primary cell wall	1473:1511	the abaxial epidermal primary cell wall	1473:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	4	33	theme	biochemical	398:408	arg1	composition					410:420	their biochemical composition	392:420	their biochemical composition	392:420	Although their biochemical composition is well known, how the different components organize in the volume of the cell wall and interact with each other is not well understood and yet is key to the wall's mechanical properties.					
35508170	2	34	theme	chemical	311:318	arg1	properties					320:329	their mechanical and chemical properties	290:329	their mechanical and chemical properties	290:329	They protect cells against the environment and high turgor and mediate morphogenesis through the dynamics of their mechanical and chemical properties.					
35508170	5	35	theme	onion	691:695	arg1	bulbs					711:715	onion (Allium cepa) bulbs	691:715	onion (Allium cepa) bulbs	691:715	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	8	36	theme	cell	1150:1153	arg1	wall					1155:1158	the cell wall	1146:1158	the cell wall	1146:1158	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	5	37	theme	milling	766:772	arg1	milling					784:790	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	milling	784:790	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	37	theme	milling	766:772	arg1	cryo-ET					823:829	cryo-ET	823:829	cryo-ET	823:829	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	8	38	theme	angular	1108:1114	arg1	distribution					1116:1127	a regular bimodal angular distribution	1090:1127	a regular bimodal angular distribution	1090:1127	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	10	39	theme	HG-rich	1649:1655	arg1	meshing					1657:1663	the surrounding HG-rich meshing	1633:1663	the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall	1633:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	5	40	theme	cryo-FIB	775:782	arg1	milling					784:790	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	milling	784:790	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	40	theme	cryo-FIB	775:782	arg1	cryo-ET					823:829	cryo-ET	823:829	cryo-ET	823:829	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	8	41	theme	bimodal	1100:1106	arg1	distribution					1116:1127	a regular bimodal angular distribution	1090:1127	a regular bimodal angular distribution	1090:1127	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	9	42	from	changes	1331:1337	arg1	meshing					1346:1352	the meshing	1342:1352	the meshing	1342:1352	Concomitantly, employing homogalacturonan (HG)-specific enzymatic digestion, we observed changes in the meshing, suggesting that it is-at least in part-composed of HG pectins.					
35508170	2	43	theme	mechanical	296:305	arg1	properties					320:329	their mechanical and chemical properties	290:329	their mechanical and chemical properties	290:329	They protect cells against the environment and high turgor and mediate morphogenesis through the dynamics of their mechanical and chemical properties.					
35508170	5	44	theme	cryo-focused	744:755	arg1	milling					784:790	cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography	744:820	milling	784:790	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	5	44	theme	cryo-focused	744:755	arg1	cryo-ET					823:829	cryo-ET	823:829	cryo-ET	823:829	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	9	45	theme	HG	1406:1407	arg1	pectins					1409:1415	HG pectins	1406:1415	HG pectins	1406:1415	Concomitantly, employing homogalacturonan (HG)-specific enzymatic digestion, we observed changes in the meshing, suggesting that it is-at least in part-composed of HG pectins.					
35508170	0	46	theme	cell	38:41	arg1	wall					43:46	the onion cell wall	28:46	the onion cell wall	28:46	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	10	47	theme	distal	1726:1731	arg1	regions					1733:1739	more distal regions	1721:1739	more distal regions of the cell wall	1721:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	8	48	theme	regular	1092:1098	arg1	distribution					1116:1127	a regular bimodal angular distribution	1090:1127	a regular bimodal angular distribution	1090:1127	The fibers adopted a regular bimodal angular distribution at all depths in the cell wall and bundled according to their orientation, creating layers within the cell wall.					
35508170	10	49	theme	cellulose	1553:1561	arg1	fibers					1563:1568	cellulose fibers	1553:1568	cellulose fibers at -45° and +45° relative to the cell's long axis	1553:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	0	50	theme	onion	32:36	arg1	wall					43:46	the onion cell wall	28:46	the onion cell wall	28:46	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	7	51	theme	wall	1065:1068	arg1	surface					1045:1051	the inner surface	1035:1051	the inner surface of the cell wall	1035:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	2	52	theme	high	228:231	arg1	turgor					233:238	high turgor	228:238	high turgor	228:238	They protect cells against the environment and high turgor and mediate morphogenesis through the dynamics of their mechanical and chemical properties.					
35508170	3	53	theme	complex	348:354	arg1	walls					336:340	The walls	332:340	The walls	332:340	The walls are a complex polysaccharidic structure.					
35508170	3	53	theme	complex	348:354	arg1	structure					372:380	a complex polysaccharidic structure	346:380	a complex polysaccharidic structure	346:380	The walls are a complex polysaccharidic structure.					
35508170	10	54	theme	wall	1508:1511	arg1	construction					1457:1468	the construction	1453:1468	the construction of the abaxial epidermal primary cell wall	1453:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	3	55	theme	polysaccharidic	356:370	arg1	walls					336:340	The walls	332:340	The walls	332:340	The walls are a complex polysaccharidic structure.					
35508170	3	55	theme	polysaccharidic	356:370	arg1	structure					372:380	a complex polysaccharidic structure	346:380	a complex polysaccharidic structure	346:380	The walls are a complex polysaccharidic structure.					
35508170	5	56	theme	cell	657:660	arg1	wall					662:665	the plant cell wall	647:665	the plant cell wall	647:665	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	7	57	from	surface	1045:1051	arg1	abundant					1023:1030	abundant	1023:1030	abundant	1023:1030	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	0	58	theme	wall	43:46	arg1	tomography					14:23	Cryo-electron tomography	0:23	Cryo-electron tomography of the onion cell wall	0:46	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	6	59	theme	fibers	893:898	arg1	visualization					866:878	the high-resolution visualization	846:878	the high-resolution visualization of cellulose fibers in situ	846:906	This allowed the high-resolution visualization of cellulose fibers in situ.					
35508170	5	60	theme	wall	662:665	arg1	ultrastructure					629:642	the ultrastructure	625:642	the ultrastructure of the plant cell wall	625:665	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	10	61	theme	wall	1753:1756	arg1	regions					1733:1739	more distal regions	1721:1739	more distal regions of the cell wall	1721:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	7	62	theme	fields	950:955	arg1	coexistence					923:933	the coexistence	919:933	the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall	919:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	10	63	theme	relative	1587:1594	arg1	and +45°					1578:1585	-45° and +45°	1573:1585	-45° and +45° relative to the cell's long axis	1573:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	6	64	theme	cellulose	883:891	arg1	fibers					893:898	cellulose fibers	883:898	cellulose fibers	883:898	This allowed the high-resolution visualization of cellulose fibers in situ.					
35508170	7	65	theme	reticulated	969:979	arg1	matrix					981:986	a reticulated matrix	967:986	a reticulated matrix we termed "meshing	967:1005	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	7	65	theme	reticulated	969:979	arg1	"					1007:1007	"	1007:1007	" which is more abundant at the inner surface of the cell wall	1007:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	10	66	theme	cell	1748:1751	arg1	wall					1753:1756	the cell wall	1744:1756	the cell wall	1744:1756	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	67	theme	-45°	1573:1576	arg1	and +45°					1578:1585	-45° and +45°	1573:1585	-45° and +45° relative to the cell's long axis	1573:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	68	theme	plasma	1681:1686	arg1	membrane					1688:1695	the plasma membrane	1677:1695	the plasma membrane	1677:1695	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	10	69	theme	long	1610:1613	arg1	axis					1615:1618	the cell's long axis	1599:1618	the cell's long axis	1599:1618	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	4	70	theme	different	445:453	arg1	components					455:464	the different components	441:464	the different components	441:464	Although their biochemical composition is well known, how the different components organize in the volume of the cell wall and interact with each other is not well understood and yet is key to the wall's mechanical properties.					
35508170	7	71	theme	dense	938:942	arg1	fields					950:955	dense fiber fields	938:955	dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall	938:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	9	72	theme	pectins	1409:1415	arg1	part-composed					1389:1401	part-composed	1389:1401	part-composed of HG pectins	1389:1415	Concomitantly, employing homogalacturonan (HG)-specific enzymatic digestion, we observed changes in the meshing, suggesting that it is-at least in part-composed of HG pectins.					
35508170	9	73	theme	-specific	1288:1296	arg1	digestion					1308:1316	homogalacturonan (HG)-specific enzymatic digestion	1267:1316	homogalacturonan (HG)-specific enzymatic digestion	1267:1316	Concomitantly, employing homogalacturonan (HG)-specific enzymatic digestion, we observed changes in the meshing, suggesting that it is-at least in part-composed of HG pectins.					
35508170	0	74	theme	oriented	64:71	arg1	fibers					83:88	bimodally oriented cellulose fibers	54:88	bimodally oriented cellulose fibers	54:88	Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks.					
35508170	7	75	theme	fiber	944:948	arg1	fields					950:955	dense fiber fields	938:955	dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall	938:1068	We reveal the coexistence of dense fiber fields bathed in a reticulated matrix we termed "meshing," which is more abundant at the inner surface of the cell wall.					
35508170	1	76	theme	plant	149:153	arg1	cells					155:159	plant cells	149:159	plant cells	149:159	One hallmark of plant cells is their cell wall.					
35508170	9	77	theme	enzymatic	1298:1306	arg1	digestion					1308:1316	homogalacturonan (HG)-specific enzymatic digestion	1267:1316	homogalacturonan (HG)-specific enzymatic digestion	1267:1316	Concomitantly, employing homogalacturonan (HG)-specific enzymatic digestion, we observed changes in the meshing, suggesting that it is-at least in part-composed of HG pectins.					
35508170	5	78	theme	bulbs	711:715	arg1	walls					682:686	the walls	678:686	the walls of onion (Allium cepa) bulbs in a near-native state	678:738	To investigate the ultrastructure of the plant cell wall, we imaged the walls of onion (Allium cepa) bulbs in a near-native state via cryo-focused ion beam milling (cryo-FIB milling) and cryo-electron tomography (cryo-ET).					
35508170	10	79	theme	primary	1495:1501	arg1	wall					1508:1511	the abaxial epidermal primary cell wall	1473:1511	the abaxial epidermal primary cell wall	1473:1511	We propose the following model for the construction of the abaxial epidermal primary cell wall: the cell deposits successive layers of cellulose fibers at -45° and +45° relative to the cell's long axis and secretes the surrounding HG-rich meshing proximal to the plasma membrane, which then migrates to more distal regions of the cell wall.					
35508170	1	80	theme	cells	155:159	arg1	hallmark					137:144	One hallmark	133:144	One hallmark of plant cells	133:159	One hallmark of plant cells is their cell wall.					
35508170	4	81	theme	mechanical	587:596	arg1	properties					598:607	the wall's mechanical properties	576:607	the wall's mechanical properties	576:607	Although their biochemical composition is well known, how the different components organize in the volume of the cell wall and interact with each other is not well understood and yet is key to the wall's mechanical properties.					
35122209	9	0	theme	cellulose	1620:1628	arg1	hydrogels					1630:1638	CONCLUSIONS Methyl cellulose hydrogels	1601:1638	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition	1601:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	7	1	theme	release	1245:1251	arg1	profiles					1253:1260	release profiles	1245:1260	release profiles	1245:1260	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	9	2	with	hydrogels	1630:1638	arg1	composition					1660:1670	optimized salt composition	1645:1670	optimized salt composition	1645:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	1	3	theme	wound	264:268	arg1	dressings					270:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	7	4	theme	drug	1133:1136	arg1	studies					1146:1152	In vitro drug release studies	1124:1152	In vitro drug release studies of various drugs	1124:1169	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	3	5	theme	cellulose	548:556	arg1	compositions					567:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	9	6	theme	salt	1655:1658	arg1	composition					1660:1670	optimized salt composition	1645:1670	optimized salt composition	1645:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	9	7	theme	dressing	1792:1799	arg1	applications					1801:1812	in situ wound dressing applications	1778:1812	in situ wound dressing applications	1778:1812	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	7	8	theme	In	1124:1125	arg1	studies					1146:1152	In vitro drug release studies	1124:1152	In vitro drug release studies of various drugs	1124:1169	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	3	9	theme	optimized	531:539	arg1	compositions					567:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	1	10	theme	cellulose	180:188	arg1	use					166:168	the use	162:168	the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings	162:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	4	11	theme	release	683:689	arg1	profiles					691:698	Printability and cumulative release profiles	655:698	Printability and cumulative release profiles for selected drugs	655:717	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	8	12	from	process	1425:1431	arg1	deviations					1389:1398	deviations	1389:1398	deviations from the actual printing process	1389:1431	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	3	13	theme	salt	562:565	arg1	compositions					567:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions	527:578	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	3	14	theme	various	602:608	arg1	drugs					610:614	various drugs	602:614	various drugs beneficial for the treatment of burns	602:652	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	9	15	theme	dressing	1717:1724	arg1	application					1726:1736	a wound dressing application	1709:1736	a wound dressing application	1709:1736	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	7	16	theme	Weibull	1357:1363	arg1	model					1365:1369	the Weibull model	1353:1369	the Weibull model	1353:1369	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	2	17	dep	METHOD	308:313	arg1	investigated					437:448	investigated	437:448	was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C)	433:524	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	7	18	dep	In	1124:1125	arg1	vitro					1127:1131	vitro	1127:1131	vitro	1127:1131	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	5	19	theme	hydrogel	928:935	arg1	filament					937:944	the hydrogel filament	924:944	the hydrogel filament	924:944	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	7	20	theme	Peppas	1336:1341	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	3	21	theme	beneficial	616:625	arg1	drugs					610:614	various drugs	602:614	various drugs beneficial for the treatment of burns	602:652	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	5	22	theme	printing	900:907	arg1	parameters					909:918	printing parameters	900:918	printing parameters	900:918	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	1	23	from	use	166:168	arg1	fabrication					197:207	the fabrication	193:207	the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings	193:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	2	24	from	effects	319:325	arg1	properties					365:374	the properties	361:374	the properties of methyl cellulose, especially the gelation temperature	361:431	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	4	25	theme	common	765:770	arg1	models					788:793	common release kinetic models	765:793	common release kinetic models	765:793	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	0	26	theme	Fluid	99:103	arg1	Dynamics					105:112	Computational Fluid Dynamics	85:112	Computational Fluid Dynamics Simulation	85:123	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	6	27	theme	moderate	1007:1014	arg1	integrity					1028:1036	moderate dimensional integrity	1007:1036	moderate dimensional integrity	1007:1036	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	9	28	theme	in	1778:1779	arg1	applications					1801:1812	in situ wound dressing applications	1778:1812	in situ wound dressing applications	1778:1812	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	8	29	theme	structure	1494:1502	arg1	shape					1473:1477	the shape	1469:1477	the shape of the printed structure	1469:1502	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	4	30	theme	kinetic	780:786	arg1	models					788:793	common release kinetic models	765:793	common release kinetic models	765:793	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	0	31	theme	Wound	38:42	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	7	32	theme	Korsmeyer	1326:1334	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	9	33	theme	wound	1786:1790	arg1	applications					1801:1812	in situ wound dressing applications	1778:1812	in situ wound dressing applications	1778:1812	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	2	34	theme	cellulose	386:394	arg1	properties					365:374	the properties	361:374	the properties of methyl cellulose, especially the gelation temperature	361:431	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	0	35	theme	3D	0:1	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	0	36	theme	Methyl	12:17	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	2	37	theme	gelation	412:419	arg1	temperature					421:431	the gelation temperature	408:431	the gelation temperature	408:431	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	2	37	theme	gelation	412:419	arg1	cellulose					386:394	methyl cellulose	379:394	methyl cellulose	379:394	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	0	38	theme	Hydrogel	29:36	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	7	39	theme	release	1298:1304	arg1	models					1306:1311	common in vitro drug release models	1277:1311	common in vitro drug release models	1277:1311	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	39	theme	release	1298:1304	arg1	model					1365:1369	the Weibull model	1353:1369	the Weibull model	1353:1369	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	39	theme	release	1298:1304	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	8	40	theme	mass	1548:1551	arg1	rate					1558:1561	mass flow rate	1548:1561	mass flow rate	1548:1561	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	2	41	theme	salts	352:356	arg1	effects					319:325	The effects	315:325	The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature	315:431	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	7	42	theme	various	1157:1163	arg1	drugs					1165:1169	various drugs	1157:1169	various drugs	1157:1169	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	8	43	theme	actual	1409:1414	arg1	process					1425:1431	the actual printing process	1405:1431	the actual printing process	1405:1431	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	2	44	theme	incorporating	330:342	arg1	salts					352:356	incorporating various salts	330:356	incorporating various salts	330:356	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	7	45	theme	common	1277:1282	arg1	models					1306:1311	common in vitro drug release models	1277:1311	common in vitro drug release models	1277:1311	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	45	theme	common	1277:1282	arg1	model					1365:1369	the Weibull model	1353:1369	the Weibull model	1353:1369	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	45	theme	common	1277:1282	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	8	46	theme	line	1567:1570	arg1	width					1572:1576	line width	1567:1576	line width	1567:1576	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	0	47	with	Dressings	44:52	arg1	Parameter					59:67	Parameter	59:67	Parameter	59:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	1	48	theme	printed	235:241	arg1	dressings					270:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	9	49	theme	Methyl	1613:1618	arg1	hydrogels					1630:1638	CONCLUSIONS Methyl cellulose hydrogels	1601:1638	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition	1601:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	7	50	theme	release	1138:1144	arg1	studies					1146:1152	In vitro drug release studies	1124:1152	In vitro drug release studies of various drugs	1124:1169	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	1	51	theme	hydrogel	255:262	arg1	dressings					270:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	6	52	theme	swelling	1103:1110	arg1	properties					1112:1121	good swelling properties	1098:1121	good swelling properties	1098:1121	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	8	53	theme	hydrogels	1590:1598	arg1	rate					1558:1561	mass flow rate	1548:1561	mass flow rate	1548:1561	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	8	53	theme	hydrogels	1590:1598	arg1	width					1572:1576	line width	1567:1576	line width	1567:1576	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	3	54	theme	methyl	541:546	arg1	cellulose					548:556	methyl cellulose	541:556	methyl cellulose	541:556	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	1	55	theme	dressings	270:278	arg1	fabrication					197:207	the fabrication	193:207	the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings	193:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	9	56	theme	optimized	1645:1653	arg1	composition					1660:1670	optimized salt composition	1645:1670	optimized salt composition	1645:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	1	57	theme	methyl	173:178	arg1	cellulose					180:188	methyl cellulose	173:188	methyl cellulose	173:188	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	5	58	theme	Fluid	810:814	arg1	CFD					826:828	CFD	826:828	CFD	826:828	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	5	58	theme	Fluid	810:814	arg1	Dynamics					816:823	Computational Fluid Dynamics	796:823	Computational Fluid Dynamics (CFD) simulation	796:840	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	4	59	theme	Printability	655:666	arg1	profiles					691:698	Printability and cumulative release profiles	655:698	Printability and cumulative release profiles for selected drugs	655:717	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	9	60	theme	suitable	1685:1692	arg1	properties					1694:1703	suitable properties	1685:1703	suitable properties	1685:1703	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	4	61	theme	cumulative	672:681	arg1	profiles					691:698	Printability and cumulative release profiles	655:698	Printability and cumulative release profiles for selected drugs	655:717	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	6	62	theme	printed	985:991	arg1	stable					1056:1061	stable	1056:1061	stable	1056:1061	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	6	62	theme	printed	985:991	arg1	hydrogels					993:1001	The printed hydrogels	981:1001	The printed hydrogels	981:1001	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	8	63	theme	CFD	1434:1436	arg1	simulation					1438:1447	CFD simulation	1434:1447	CFD simulation	1434:1447	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	8	64	dep	rate	1558:1561	arg1	the					1544:1546	the	1544:1546	the	1544:1546	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	1	65	theme	three-dimensional	212:228	arg1	dressings					270:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	9	66	theme	wound	1711:1715	arg1	application					1726:1736	a wound dressing application	1709:1736	a wound dressing application	1709:1736	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	6	67	dep	RESULTS	973:979	arg1	found					1044:1048	found	1044:1048	were found to be stable for up to 2 weeks	1039:1079	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	6	67	dep	RESULTS	973:979	arg1	demonstrated					1085:1096	demonstrated	1085:1096	demonstrated good swelling properties	1085:1121	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	6	67	dep	RESULTS	973:979	arg1	had					1003:1005	had	1003:1005	had moderate dimensional integrity	1003:1036	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	9	68	dep	in	1778:1779	arg1	situ					1781:1784	situ	1781:1784	situ	1781:1784	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	1	69	dep	three-dimensional	212:228	arg1	3D					231:232	3D	231:232	3D	231:232	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	7	70	theme	various	1216:1222	arg1	drugs					1224:1228	various drugs	1216:1228	various drugs	1216:1228	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	0	71	theme	Computational	85:97	arg1	Dynamics					105:112	Computational Fluid Dynamics	85:112	Computational Fluid Dynamics Simulation	85:123	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	2	72	theme	skin	494:497	arg1	31.7°C					518:523	31.7°C	518:523	31.7°C	518:523	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	2	72	theme	skin	494:497	arg1	temperature					499:509	skin temperature	494:509	skin temperature (i.e., 31.7°C)	494:524	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	8	73	theme	printed	1486:1492	arg1	structure					1494:1502	the printed structure	1482:1502	the printed structure	1482:1502	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	4	74	theme	selected	704:711	arg1	drugs					713:717	selected drugs	704:717	selected drugs	704:717	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	0	75	theme	Dynamics	105:112	arg1	Simulation					114:123	Computational Fluid Dynamics Simulation	85:123	Computational Fluid Dynamics Simulation	85:123	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	6	76	theme	dimensional	1016:1026	arg1	integrity					1028:1036	moderate dimensional integrity	1007:1036	moderate dimensional integrity	1007:1036	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	7	77	dep	in	1284:1285	arg1	vitro					1287:1291	vitro	1287:1291	vitro	1287:1291	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	6	78	theme	good	1098:1101	arg1	properties					1112:1121	good swelling properties	1098:1121	good swelling properties	1098:1121	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	8	79	theme	fair	1515:1518	arg1	accuracy					1520:1527	fair accuracy	1515:1527	fair accuracy	1515:1527	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	4	80	theme	release	772:778	arg1	models					788:793	common release kinetic models	765:793	common release kinetic models	765:793	Printability and cumulative release profiles for selected drugs were then obtained, which were then fitted to common release kinetic models.					
35122209	5	81	theme	Dynamics	816:823	arg1	simulation					831:840	Computational Fluid Dynamics (CFD) simulation	796:840	Computational Fluid Dynamics (CFD) simulation	796:840	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	2	82	theme	methyl	454:459	arg1	cellulose					461:469	methyl cellulose	454:469	methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C)	454:524	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	2	83	theme	methyl	379:384	arg1	temperature					421:431	the gelation temperature	408:431	the gelation temperature	408:431	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	2	83	theme	methyl	379:384	arg1	cellulose					386:394	methyl cellulose	379:394	methyl cellulose	379:394	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	0	84	theme	Cellulose	19:27	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	2	85	dep	31.7°C	518:523	arg1	i.e.					512:515	i.e.	512:515	i.e.	512:515	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	3	86	theme	burns	648:652	arg1	treatment					635:643	the treatment	631:643	the treatment of burns	631:652	The optimized methyl cellulose and salt compositions were then loaded with various drugs beneficial for the treatment of burns.					
35122209	7	87	theme	drugs	1165:1169	arg1	studies					1146:1152	In vitro drug release studies	1124:1152	In vitro drug release studies of various drugs	1124:1169	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	1	88	theme	burns	301:305	arg1	treatment					288:296	the treatment	284:296	the treatment of burns	284:305	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35122209	7	89	theme	drug	1293:1296	arg1	models					1306:1311	common in vitro drug release models	1277:1311	common in vitro drug release models	1277:1311	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	89	theme	drug	1293:1296	arg1	model					1365:1369	the Weibull model	1353:1369	the Weibull model	1353:1369	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	89	theme	drug	1293:1296	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	8	90	theme	flow	1553:1556	arg1	rate					1558:1561	mass flow rate	1548:1561	mass flow rate	1548:1561	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	5	91	theme	Computational	796:808	arg1	CFD					826:828	CFD	826:828	CFD	826:828	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	5	91	theme	Computational	796:808	arg1	Dynamics					816:823	Computational Fluid Dynamics	796:823	Computational Fluid Dynamics (CFD) simulation	796:840	Computational Fluid Dynamics (CFD) simulation was also explored to investigate the relationship between printing parameters and the hydrogel filament produced during extrusion.					
35122209	7	92	theme	in	1284:1285	arg1	models					1306:1311	common in vitro drug release models	1277:1311	common in vitro drug release models	1277:1311	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	92	theme	in	1284:1285	arg1	model					1365:1369	the Weibull model	1353:1369	the Weibull model	1353:1369	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	7	92	theme	in	1284:1285	arg1	model					1343:1347	the Korsmeyer Peppas model	1322:1347	the Korsmeyer Peppas model	1322:1347	In vitro drug release studies of various drugs showed that the hydrogel was able to release various drugs within 6 h and release profiles were fitted to common in vitro drug release models, such as the Korsmeyer Peppas model and the Weibull model.					
35122209	6	93	contain	had	1003:1005	arg1	stable					1056:1061	stable	1056:1061	stable	1056:1061	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	6	93	contain	had	1003:1005	arg1	hydrogels					993:1001	The printed hydrogels	981:1001	The printed hydrogels	981:1001	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	6	93	contain	had	1003:1005	arg2	integrity					1028:1036	moderate dimensional integrity	1007:1036	moderate dimensional integrity	1007:1036	RESULTS The printed hydrogels had moderate dimensional integrity, were found to be stable for up to 2 weeks and demonstrated good swelling properties.					
35122209	2	94	theme	various	344:350	arg1	salts					352:356	incorporating various salts	330:356	incorporating various salts	330:356	METHOD The effects of incorporating various salts on the properties of methyl cellulose, especially the gelation temperature was investigated for methyl cellulose to undergo gelation at skin temperature (i.e., 31.7°C).					
35122209	9	95	theme	CONCLUSIONS	1601:1611	arg1	hydrogels					1630:1638	CONCLUSIONS Methyl cellulose hydrogels	1601:1638	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition	1601:1670	CONCLUSIONS Methyl cellulose hydrogels with optimized salt composition demonstrated suitable properties for a wound dressing application, revealing its potential to be used for in situ wound dressing applications.					
35122209	8	96	theme	extruded	1581:1588	arg1	hydrogels					1590:1598	extruded hydrogels	1581:1598	extruded hydrogels	1581:1598	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	8	97	theme	printing	1416:1423	arg1	process					1425:1431	the actual printing process	1405:1431	the actual printing process	1405:1431	While there were deviations from the actual printing process, CFD simulation was able to predict the shape of the printed structure and showed fair accuracy in determining the mass flow rate and line width of extruded hydrogels.					
35122209	0	98	theme	Printing	3:10	arg1	Dressings					44:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings	0:52	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter	0:67	3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation.					
35122209	1	99	theme	drug-loaded	243:253	arg1	dressings					270:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	three-dimensional (3D) printed drug-loaded hydrogel wound dressings	212:278	PURPOSE To investigate and optimize the use of methyl cellulose in the fabrication of three-dimensional (3D) printed drug-loaded hydrogel wound dressings for the treatment of burns.					
35355444	6	0	theme	tissue	1264:1269	arg1	regeneration					1271:1282	tissue regeneration	1264:1282	tissue regeneration	1264:1282	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	5	1	dep	in	1025:1026	arg1	vivo					1028:1031	vivo	1028:1031	vivo	1028:1031	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	2	2	theme	versatile	411:419	arg1	engineering					428:438	versatile tissue engineering	411:438	versatile tissue engineering	411:438	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	6	3	theme	nanowires/alginate	1154:1171	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	3	4	contain	possess	595:601	arg1	hydrogels					585:593	the obtained composite hydrogels	562:593	the obtained composite hydrogels	562:593	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	3	4	contain	possess	595:601	arg2	architectures					629:641	bioinspired reinforcement architectures	603:641	bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties	603:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	5	5	theme	tissue	1033:1038	arg1	regeneration					1040:1051	in vivo tissue regeneration	1025:1051	in vivo tissue regeneration	1025:1051	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	3	6	theme	composite	575:583	arg1	hydrogels					585:593	the obtained composite hydrogels	562:593	the obtained composite hydrogels	562:593	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	2	7	used	utilized	322:329	arg2	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	7	used	utilized	322:329	arg2	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	7	used	utilized	322:329	arg2	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	6	8	theme	silicate	1145:1152	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	3	9	with	microscale	671:680	arg1	properties					721:730	significantly enhanced mechanical properties	687:730	significantly enhanced mechanical properties	687:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	4	10	theme	stem	913:916	arg1	cells					918:922	rabbit tendon stem cells	899:922	rabbit tendon stem cells	899:922	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	4	11	theme	scaffolds	798:806	arg1	cues					767:770	The biochemical and topographical cues	733:770	The biochemical and topographical cues of the composite hydrogel scaffolds	733:806	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	4	12	theme	mesenchymal	872:882	arg1	cells					889:893	the rabbit bone mesenchymal stem cells	856:893	the rabbit bone mesenchymal stem cells	856:893	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	6	13	theme	calcium	1137:1143	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	5	14	dep	tendon	1066:1071	arg1	bone					1058:1061	bone	1058:1061	bone	1058:1061	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	5	14	dep	tendon	1066:1071	arg1	tissue					1113:1118	fibrocartilage transitional tissue	1085:1118	fibrocartilage transitional tissue	1085:1118	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	3	15	theme	obtained	566:573	arg1	hydrogels					585:593	the obtained composite hydrogels	562:593	the obtained composite hydrogels	562:593	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	5	16	theme	composite	988:996	arg1	hydrogels					998:1006	The composite hydrogels	984:1006	The composite hydrogels	984:1006	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	7	17	theme	multiscale	1360:1369	arg1	scaffolds					1403:1411	multiscale hierarchical architecture-based scaffolds	1360:1411	multiscale hierarchical architecture-based scaffolds for tendon/bone engineering	1360:1439	This work provides an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering.					
35355444	1	18	theme	Artificial	97:106	arg1	construction					108:119	Artificial construction	97:119	Artificial construction from tendon to bone	97:139	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	3	19	theme	printing	479:486	arg1	technology					488:497	3D printing technology	476:497	3D printing technology	476:497	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	3	20	dep	microscale	671:680	arg1	to					668:669	to	668:669	to	668:669	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	6	21	theme	such	1132:1135	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	6	22	contain	have	1233:1236	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	6	22	contain	have	1233:1236	arg2	application					1248:1258	potential application	1238:1258	potential application for tissue regeneration	1238:1282	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	4	23	theme	improved	958:965	arg1	differentiation					967:981	improved differentiation	958:981	improved differentiation	958:981	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	3	24	theme	reinforcement	615:627	arg1	architectures					629:641	bioinspired reinforcement architectures	603:641	bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties	603:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	3	25	theme	mechanical	503:512	arg1	stretch					514:520	mechanical stretch post-treatment	503:535	mechanical stretch post-treatment	503:535	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	0	26	theme	Hierarchical	11:22	arg1	Scaffolds					53:61	Hierarchical Architecture-Based Bioactive Scaffolds	11:61	Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering	11:94	Multiscale Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering.					
35355444	6	27	dep	bone	1299:1302	arg1	tendon					1289:1294	tendon	1289:1294	tendon	1289:1294	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	1	28	from	challenge	162:170	arg1	engineering					182:192	tissue engineering	175:192	tissue engineering owing to their structural complexity	175:229	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	4	29	theme	bone	867:870	arg1	cells					889:893	the rabbit bone mesenchymal stem cells	856:893	the rabbit bone mesenchymal stem cells	856:893	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	7	30	theme	hierarchical	1371:1382	arg1	scaffolds					1403:1411	multiscale hierarchical architecture-based scaffolds	1360:1411	multiscale hierarchical architecture-based scaffolds for tendon/bone engineering	1360:1439	This work provides an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering.					
35355444	1	31	theme	structural	209:218	arg1	complexity					220:229	their structural complexity	203:229	their structural complexity	203:229	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	7	32	theme	architecture-based	1384:1401	arg1	scaffolds					1403:1411	multiscale hierarchical architecture-based scaffolds	1360:1411	multiscale hierarchical architecture-based scaffolds for tendon/bone engineering	1360:1439	This work provides an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering.					
35355444	4	33	theme	tendon	906:911	arg1	cells					918:922	rabbit tendon stem cells	899:922	rabbit tendon stem cells	899:922	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	4	34	theme	rabbit	860:865	arg1	cells					889:893	the rabbit bone mesenchymal stem cells	856:893	the rabbit bone mesenchymal stem cells	856:893	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	4	35	theme	composite	779:787	arg1	scaffolds					798:806	the composite hydrogel scaffolds	775:806	the composite hydrogel scaffolds	775:806	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	0	36	theme	Bioactive	43:51	arg1	Scaffolds					53:61	Hierarchical Architecture-Based Bioactive Scaffolds	11:61	Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering	11:94	Multiscale Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering.					
35355444	3	37	theme	mechanical	710:719	arg1	properties					721:730	significantly enhanced mechanical properties	687:730	significantly enhanced mechanical properties	687:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	4	38	theme	stem	884:887	arg1	cells					889:893	the rabbit bone mesenchymal stem cells	856:893	the rabbit bone mesenchymal stem cells	856:893	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	4	39	theme	ordered	936:942	arg1	alignment					944:952	ordered alignment	936:952	ordered alignment	936:952	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	6	40	theme	potential	1238:1246	arg1	application					1248:1258	potential application	1238:1258	potential application for tissue regeneration	1238:1282	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	0	41	theme	Architecture-Based	24:41	arg1	Scaffolds					53:61	Hierarchical Architecture-Based Bioactive Scaffolds	11:61	Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering	11:94	Multiscale Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering.					
35355444	3	42	theme	bioinspired	603:613	arg1	architectures					629:641	bioinspired reinforcement architectures	603:641	bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties	603:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	2	43	theme	building	334:341	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	43	theme	building	334:341	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	43	theme	building	334:341	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	4	44	theme	biochemical	737:747	arg1	cues					767:770	The biochemical and topographical cues	733:770	The biochemical and topographical cues of the composite hydrogel scaffolds	733:806	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	7	45	theme	tendon/bone	1417:1427	arg1	engineering					1429:1439	tendon/bone engineering	1417:1439	tendon/bone engineering	1417:1439	This work provides an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering.					
35355444	4	46	theme	hydrogel	789:796	arg1	scaffolds					798:806	the composite hydrogel scaffolds	775:806	the composite hydrogel scaffolds	775:806	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	2	47	theme	silicate	266:273	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	47	theme	silicate	266:273	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	47	theme	silicate	266:273	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	3	48	theme	3D	476:477	arg1	technology					488:497	3D printing technology	476:497	3D printing technology	476:497	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	2	49	theme	calcium	258:264	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	49	theme	calcium	258:264	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	49	theme	calcium	258:264	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	3	50	theme	post-treatment	522:535	arg1	stretch					514:520	mechanical stretch post-treatment	503:535	mechanical stretch post-treatment	503:535	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	0	51	theme	Tissue	77:82	arg1	Engineering					84:94	Versatile Tissue Engineering	67:94	Versatile Tissue Engineering	67:94	Multiscale Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering.					
35355444	5	52	theme	in	1025:1026	arg1	regeneration					1040:1051	in vivo tissue regeneration	1025:1051	in vivo tissue regeneration	1025:1051	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	6	53	theme	hierarchical	1209:1220	arg1	structures					1222:1231	multiscale hierarchical structures	1198:1231	multiscale hierarchical structures	1198:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	2	54	theme	bioinspired	246:256	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	54	theme	bioinspired	246:256	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	54	theme	bioinspired	246:256	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	6	55	with	hydrogels	1183:1191	arg1	structures					1222:1231	multiscale hierarchical structures	1198:1231	multiscale hierarchical structures	1198:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	0	56	theme	Versatile	67:75	arg1	Engineering					84:94	Versatile Tissue Engineering	67:94	Versatile Tissue Engineering	67:94	Multiscale Hierarchical Architecture-Based Bioactive Scaffolds for Versatile Tissue Engineering.					
35355444	3	57	theme	confined	542:549	arg1	condition					551:559	a confined condition	540:559	a confined condition	540:559	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	1	58	theme	tissue	175:180	arg1	engineering					182:192	tissue engineering	175:192	tissue engineering owing to their structural complexity	175:229	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	2	59	theme	bioactive	387:395	arg1	scaffolds					397:405	multiscale hierarchical bioactive scaffolds	363:405	multiscale hierarchical bioactive scaffolds for versatile tissue engineering	363:438	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	3	60	from	nano-	648:652	arg1	architectures					629:641	bioinspired reinforcement architectures	603:641	bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties	603:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	7	61	theme	innovative	1327:1336	arg1	strategy					1338:1345	an innovative strategy	1324:1345	an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering	1324:1439	This work provides an innovative strategy to construct multiscale hierarchical architecture-based scaffolds for tendon/bone engineering.					
35355444	2	62	theme	composite	298:306	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	62	theme	composite	298:306	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	62	theme	composite	298:306	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	3	63	theme	enhanced	701:708	arg1	properties					721:730	significantly enhanced mechanical properties	687:730	significantly enhanced mechanical properties	687:730	By integrating 3D printing technology and mechanical stretch post-treatment in a confined condition, the obtained composite hydrogels possess bioinspired reinforcement architectures from nano- to submicron- to microscale with significantly enhanced mechanical properties.					
35355444	1	64	theme	formidable	151:160	arg1	challenge					162:170	a formidable challenge	149:170	a formidable challenge in tissue engineering owing to their structural complexity	149:229	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	5	65	theme	fibrocartilage	1085:1098	arg1	tissue					1113:1118	fibrocartilage transitional tissue	1085:1118	fibrocartilage transitional tissue	1085:1118	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	6	66	theme	multiscale	1198:1207	arg1	structures					1222:1231	multiscale hierarchical structures	1198:1231	multiscale hierarchical structures	1198:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	4	67	theme	rabbit	899:904	arg1	cells					918:922	rabbit tendon stem cells	899:922	rabbit tendon stem cells	899:922	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	2	68	theme	alginate	289:296	arg1	blocks					343:348	building blocks	334:348	building blocks	334:348	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	68	theme	alginate	289:296	arg1	hydrogels					308:316	alginate composite hydrogels	289:316	alginate composite hydrogels	289:316	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	68	theme	alginate	289:296	arg1	nanowires					275:283	bioinspired calcium silicate nanowires	246:283	bioinspired calcium silicate nanowires	246:283	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	69	theme	multiscale	363:372	arg1	scaffolds					397:405	multiscale hierarchical bioactive scaffolds	363:405	multiscale hierarchical bioactive scaffolds for versatile tissue engineering	363:438	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	2	70	theme	hierarchical	374:385	arg1	scaffolds					397:405	multiscale hierarchical bioactive scaffolds	363:405	multiscale hierarchical bioactive scaffolds for versatile tissue engineering	363:438	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	4	71	theme	topographical	753:765	arg1	cues					767:770	The biochemical and topographical cues	733:770	The biochemical and topographical cues of the composite hydrogel scaffolds	733:806	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35355444	2	72	dep	bone	455:458	arg1	tendon					445:450	tendon	445:450	tendon	445:450	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	5	73	theme	transitional	1100:1111	arg1	tissue					1113:1118	fibrocartilage transitional tissue	1085:1118	fibrocartilage transitional tissue	1085:1118	The composite hydrogels markedly promote in vivo tissue regeneration from bone to tendon, especially fibrocartilage transitional tissue.					
35355444	1	74	from	tendon	126:131	arg1	construction					108:119	Artificial construction	97:119	Artificial construction from tendon to bone	97:139	Artificial construction from tendon to bone remains a formidable challenge in tissue engineering owing to their structural complexity.					
35355444	6	75	theme	composite	1173:1181	arg1	hydrogels					1183:1191	such calcium silicate nanowires/alginate composite hydrogels	1132:1191	such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures	1132:1231	Therefore, such calcium silicate nanowires/alginate composite hydrogels with multiscale hierarchical structures have potential application for tissue regeneration from tendon to bone.					
35355444	2	76	theme	tissue	421:426	arg1	engineering					428:438	versatile tissue engineering	411:438	versatile tissue engineering	411:438	In this work, bioinspired calcium silicate nanowires and alginate composite hydrogels are utilized as building blocks to construct multiscale hierarchical bioactive scaffolds for versatile tissue engineering from tendon to bone.					
35355444	4	77	theme	efficient	826:834	arg1	microenvironment					836:851	much more efficient microenvironment	816:851	much more efficient microenvironment	816:851	The biochemical and topographical cues of the composite hydrogel scaffolds provide much more efficient microenvironment to the rabbit bone mesenchymal stem cells and rabbit tendon stem cells, leading to ordered alignment and improved differentiation.					
35175780	5	0	theme	batch	755:759	arg1	reactions					761:769	batch reactions	755:769	batch reactions	755:769	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	3	1	theme	X-ray	479:483	arg1	XPS					513:515	XPS	513:515	XPS	513:515	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	3	1	theme	X-ray	479:483	arg1	spectroscopy					499:510	X-ray photoelectron spectroscopy	479:510	X-ray photoelectron spectroscopy (XPS)	479:516	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	8	2	theme	catalytic	1113:1121	arg1	layer					1123:1127	a spongy porous catalytic layer	1097:1127	a spongy porous catalytic layer	1097:1127	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	3	3	theme	photoelectron	485:497	arg1	XPS					513:515	XPS	513:515	XPS	513:515	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	3	3	theme	photoelectron	485:497	arg1	spectroscopy					499:510	X-ray photoelectron spectroscopy	479:510	X-ray photoelectron spectroscopy (XPS)	479:516	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	8	4	with	membrane	1083:1090	arg1	layer					1123:1127	a spongy porous catalytic layer	1097:1127	a spongy porous catalytic layer	1097:1127	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	7	5	theme	total	1030:1034	arg1	resistance					1036:1045	total resistance	1030:1045	total resistance	1030:1045	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	3	6	dep	Fourier	428:434	arg1	transform					436:444	transform	436:444	transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results	436:524	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	6	7	theme	catalytic	873:881	arg1	activity					883:890	outstanding catalytic activity	861:890	outstanding catalytic activity	861:890	After five cycles, the membrane still maintained outstanding catalytic activity.					
35175780	3	8	dep	spectroscopy	462:473	arg1	results					518:524	results	518:524	results	518:524	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	6	9	theme	outstanding	861:871	arg1	activity					883:890	outstanding catalytic activity	861:890	outstanding catalytic activity	861:890	After five cycles, the membrane still maintained outstanding catalytic activity.					
35175780	8	10	theme	catalytic	1164:1172	arg1	performance					1174:1184	catalytic performance	1164:1184	catalytic performance	1164:1184	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	0	11	theme	PVA-g-SPA/PVA-SA	7:22	arg1	Membrane					44:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane	0:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.	0:102	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.					
35175780	1	12	theme	catalytic	106:114	arg1	membrane					126:133	A catalytic composite membrane	104:133	A catalytic composite membrane	104:133	A catalytic composite membrane was developed for the enhancement of esterification by lyophilization for the first time.					
35175780	5	13	dep	h.	738:739	arg1	increased					792:800	increased	792:800	increased by 24.4%	792:809	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	1	14	theme	first	213:217	arg1	time					219:222	the first time	209:222	the first time	209:222	A catalytic composite membrane was developed for the enhancement of esterification by lyophilization for the first time.					
35175780	0	15	theme	Porous	0:5	arg1	Membrane					44:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane	0:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.	0:102	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.					
35175780	8	16	theme	composite	1073:1081	arg1	membrane					1083:1090	The composite membrane	1069:1090	The composite membrane with a spongy porous catalytic layer	1069:1127	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	7	17	theme	mass	911:914	arg1	transfer					916:923	mass transfer	911:923	mass transfer	911:923	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	2	18	theme	alginate	309:316	arg1	layer					334:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	2	19	theme	catalytic	360:368	arg1	layer					370:374	a spongy porous catalytic layer	344:374	a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA)	344:425	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	0	20	theme	Composite	34:42	arg1	Membrane					44:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane	0:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.	0:102	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.					
35175780	3	21	dep	infrared	446:453	arg1	FTIR					456:459	FTIR	456:459	FTIR	456:459	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	5	22	theme	acetic	703:708	arg1	acid					710:713	acetic acid	703:713	acetic acid	703:713	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	3	23	theme	catalytic	568:576	arg1	membrane					588:595	the catalytic composite membrane	564:595	the catalytic composite membrane	564:595	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	2	24	theme	-sodium	301:307	arg1	layer					334:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	3	25	theme	infrared	446:453	arg1	spectroscopy					462:473	infrared (FTIR) spectroscopy	446:473	infrared (FTIR) spectroscopy	446:473	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	1	26	theme	composite	116:124	arg1	membrane					126:133	A catalytic composite membrane	104:133	A catalytic composite membrane	104:133	A catalytic composite membrane was developed for the enhancement of esterification by lyophilization for the first time.					
35175780	5	27	theme	acid	710:713	arg1	rate					695:698	The conversion rate	680:698	The conversion rate of acetic acid	680:713	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	3	28	theme	successful	540:549	arg1	synthesis					551:559	the successful synthesis	536:559	the successful synthesis of the catalytic composite membrane	536:595	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	2	29	theme	4-sulfophthalic	400:414	arg1	SPA					422:424	SPA	422:424	SPA	422:424	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	2	29	theme	4-sulfophthalic	400:414	arg1	acid					416:419	4-sulfophthalic acid	400:419	4-sulfophthalic acid (SPA)	400:425	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	7	30	dep	32.88	1061:1065	arg1	to					1058:1059	to	1058:1059	to	1058:1059	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	3	31	theme	composite	578:586	arg1	membrane					588:595	the catalytic composite membrane	564:595	the catalytic composite membrane	564:595	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	4	32	theme	ethanol	640:646	arg1	dehydration					648:658	ethanol dehydration	640:658	ethanol dehydration	640:658	The membrane properties were evaluated by ethanol dehydration and esterification.					
35175780	3	33	theme	membrane	588:595	arg1	synthesis					551:559	the successful synthesis	536:559	the successful synthesis of the catalytic composite membrane	536:595	Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) results indicated the successful synthesis of the catalytic composite membrane.					
35175780	5	34	theme	conversion	776:785	arg1	rate					787:790	the conversion rate	772:790	the conversion rate	772:790	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	8	35	theme	superior	1139:1146	arg1	dehydration					1148:1158	superior dehydration	1139:1158	superior dehydration	1139:1158	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	8	36	theme	spongy	1099:1104	arg1	layer					1123:1127	a spongy porous catalytic layer	1097:1127	a spongy porous catalytic layer	1097:1127	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	7	37	theme	catalytic	1000:1008	arg1	resistance					1016:1025	the catalytic layer resistance	996:1025	the catalytic layer resistance to total resistance	996:1045	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	5	38	theme	conversion	684:693	arg1	rate					695:698	The conversion rate	680:698	The conversion rate of acetic acid	680:713	The conversion rate of acetic acid reached 95.9% after 12 h. Compared with batch reactions, the conversion rate increased by 24.4%.					
35175780	2	39	theme	composite	239:247	arg1	membrane					249:256	The catalytic composite membrane	225:256	The catalytic composite membrane	225:256	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	1	40	theme	esterification	172:185	arg1	enhancement					157:167	the enhancement	153:167	the enhancement of esterification by lyophilization	153:203	A catalytic composite membrane was developed for the enhancement of esterification by lyophilization for the first time.					
35175780	2	41	theme	separation	323:332	arg1	layer					334:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	7	42	theme	transfer	916:923	arg1	resistance					897:906	The resistance	893:906	The resistance of mass transfer	893:923	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	7	43	theme	layer	1010:1014	arg1	resistance					1016:1025	the catalytic layer resistance	996:1025	the catalytic layer resistance to total resistance	996:1045	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	2	44	theme	catalytic	229:237	arg1	membrane					249:256	The catalytic composite membrane	225:256	The catalytic composite membrane	225:256	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	2	45	theme	vinyl	281:285	arg1	poly					276:279	a poly	274:279	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	2	45	theme	vinyl	281:285	arg1	alcohol					287:293	vinyl alcohol	281:293	vinyl alcohol	281:293	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	2	46	theme	SA	319:320	arg1	layer					334:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	8	47	theme	porous	1106:1111	arg1	layer					1123:1127	a spongy porous catalytic layer	1097:1127	a spongy porous catalytic layer	1097:1127	The composite membrane with a spongy porous catalytic layer exhibited superior dehydration and catalytic performance.					
35175780	2	48	theme	poly	276:279	arg1	layer					334:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer	274:338	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	7	49	theme	porous	971:976	arg1	structure					978:986	the porous structure	967:986	the porous structure	967:986	The resistance of mass transfer was analyzed, and the results showed that the porous structure reduced the catalytic layer resistance to total resistance from 70.27 to 32.88%.					
35175780	2	50	theme	porous	353:358	arg1	layer					370:374	a spongy porous catalytic layer	344:374	a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA)	344:425	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	0	51	theme	Esterification	76:89	arg1	Enhancement					91:101	Esterification Enhancement	76:101	Esterification Enhancement	76:101	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.					
35175780	0	52	theme	Catalytic	24:32	arg1	Membrane					44:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane	0:51	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.	0:102	Porous PVA-g-SPA/PVA-SA Catalytic Composite Membrane via Lyophilization for Esterification Enhancement.					
35175780	2	53	theme	spongy	346:351	arg1	layer					370:374	a spongy porous catalytic layer	344:374	a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA)	344:425	The catalytic composite membrane was composed of a poly(vinyl alcohol) (PVA)-sodium alginate (SA) separation layer and a spongy porous catalytic layer cross-linked by PVA and 4-sulfophthalic acid (SPA).					
35175780	4	54	theme	membrane	602:609	arg1	properties					611:620	The membrane properties	598:620	The membrane properties	598:620	The membrane properties were evaluated by ethanol dehydration and esterification.					
36876801	0	0	theme	wound	79:83	arg1	care					85:88	wound care	79:88	wound care	79:88	A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care.					
36876801	4	1	theme	cellular	609:616	arg1	migration					618:626	enhanced cellular migration	600:626	enhanced cellular migration (1.58-fold) in-vitro	600:647	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	1	theme	cellular	609:616	arg1	1.58-fold					629:637	1.58-fold	629:637	1.58-fold	629:637	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	5	2	theme	body	882:885	arg1	clearance					887:895	ample body clearance	876:895	ample body clearance	876:895	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	1	3	theme	hemostatic	137:146	arg1	potential					148:156	the hemostatic potential	133:156	the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ)	133:222	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	5	4	theme	ample	876:880	arg1	clearance					887:895	ample body clearance	876:895	ample body clearance	876:895	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	4	5	theme	7th-day	744:750	arg1	creation					763:770	the 7th-day post-wound creation in-vivo	740:778	the 7th-day post-wound creation in-vivo (p < 0.005)	740:790	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	5	theme	7th-day	744:750	arg1	p < 0.005					781:789	p < 0.005	781:789	p < 0.005	781:789	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	2	6	from	reduction	309:317	arg1	time					334:337	coagulation time	322:337	coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood	322:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	4	7	theme	wound	662:666	arg1	closure					668:674	wound closure	662:674	wound closure (≈70 %)	662:682	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	7	theme	wound	662:666	arg1	%					681:681	≈70 %	677:681	≈70 %	677:681	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	5	8	theme	hydrogel	858:865	arg1	implantation					806:817	Subcutaneous implantation	793:817	Subcutaneous implantation	793:817	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	5	8	theme	hydrogel	858:865	arg1	gamma-scintigraphy					836:853	intra-venous gamma-scintigraphy	823:853	intra-venous gamma-scintigraphy	823:853	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	2	9	theme	better	344:349	arg1	BCI					376:378	BCI	376:378	BCI	376:378	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	9	theme	better	344:349	arg1	index					369:373	better blood coagulation index	344:373	better blood coagulation index (BCI)	344:379	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	4	10	theme	in-vitro	640:647	arg1	migration					618:626	enhanced cellular migration	600:626	enhanced cellular migration (1.58-fold) in-vitro	600:647	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	10	theme	in-vitro	640:647	arg1	1.58-fold					629:637	1.58-fold	629:637	1.58-fold	629:637	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	6	11	theme	efficient	1045:1053	arg1	hemostasis					1055:1064	efficient hemostasis	1045:1064	efficient hemostasis	1045:1064	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	2	12	theme	evident	388:394	arg1	hemolysis					396:404	no evident hemolysis	385:404	no evident hemolysis in human blood	385:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	13	theme	in-vitro	259:266	arg1	efficacy					268:275	substantial in-vitro efficacy	247:275	substantial in-vitro efficacy	247:275	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	1	14	theme	sodium	161:166	arg1	Ca2+					183:186	sodium alginate-based Ca2+	161:186	sodium alginate-based Ca2+	161:186	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	6	15	theme	healing	1076:1082	arg1	qualities					1084:1092	efficient hemostasis and wound healing qualities	1045:1092	efficient hemostasis and wound healing qualities	1045:1092	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	2	16	theme	significant	297:307	arg1	reduction					309:317	the significant reduction	293:317	the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood	293:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	3	17	theme	mean	476:479	arg1	loss					487:490	mean blood loss	476:490	mean blood loss (≈65 %)	476:498	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	17	theme	mean	476:479	arg1	%					497:497	≈65 %	493:497	≈65 %	493:497	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	1	18	theme	alginate-based	168:181	arg1	Ca2+					183:186	sodium alginate-based Ca2+	161:186	sodium alginate-based Ca2+	161:186	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	5	19	from	clearance	887:895	arg1	organ					944:948	any vital organ	934:948	any vital organ	934:948	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	6	20	theme	bleeding	1146:1153	arg1	wounds					1155:1160	bleeding wounds	1146:1160	bleeding wounds	1146:1160	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	6	21	theme	wound	1070:1074	arg1	healing					1076:1082	wound healing	1070:1082	wound healing	1070:1082	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	1	22	theme	Ca2+	183:186	arg1	potential					148:156	the hemostatic potential	133:156	the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ)	133:222	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	0	23	theme	zinc	14:17	arg1	hydrogel					38:45	A calcium and zinc composite alginate hydrogel	0:45	hydrogel	38:45	A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care.					
36876801	5	24	theme	Subcutaneous	793:804	arg1	implantation					806:817	Subcutaneous implantation	793:817	Subcutaneous implantation	793:817	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	5	25	theme	intra-venous	823:834	arg1	gamma-scintigraphy					836:853	intra-venous gamma-scintigraphy	823:853	intra-venous gamma-scintigraphy	823:853	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	5	26	theme	non-thromboembolic	963:980	arg1	nature					982:987	its non-thromboembolic nature	959:987	its non-thromboembolic nature	959:987	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	6	27	theme	hemostasis	1055:1064	arg1	qualities					1084:1092	efficient hemostasis and wound healing qualities	1045:1092	efficient hemostasis and wound healing qualities	1045:1092	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	5	28	from	accumulation	918:929	arg1	organ					944:948	any vital organ	934:948	any vital organ	934:948	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	1	29	theme	Zn2+	192:195	arg1	potential					148:156	the hemostatic potential	133:156	the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ)	133:222	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	0	30	theme	alginate	29:36	arg1	hydrogel					38:45	A calcium and zinc composite alginate hydrogel	0:45	hydrogel	38:45	A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care.					
36876801	6	31	theme	good	1012:1015	arg1	biocompatibility					1017:1032	good biocompatibility	1012:1032	good biocompatibility	1012:1032	Overall, SA-CZ showed good biocompatibility along with efficient hemostasis and wound healing qualities, making it suitable as a safe and effective aid for bleeding wounds.					
36876801	3	32	theme	liver	525:529	arg1	incision					531:538	the tail bleeding and liver incision	503:538	incision	531:538	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	1	33	theme	composite	197:205	arg1	SA-CZ					217:221	SA-CZ	217:221	SA-CZ	217:221	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	1	33	theme	composite	197:205	arg1	hydrogel					207:214	composite hydrogel	197:214	composite hydrogel (SA-CZ)	197:222	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	0	34	theme	composite	19:27	arg1	hydrogel					38:45	A calcium and zinc composite alginate hydrogel	0:45	hydrogel	38:45	A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care.					
36876801	2	35	with	time	334:337	arg1	BCI					376:378	BCI	376:378	BCI	376:378	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	35	with	time	334:337	arg1	index					369:373	better blood coagulation index	344:373	better blood coagulation index (BCI)	344:379	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	35	with	time	334:337	arg1	hemolysis					396:404	no evident hemolysis	385:404	no evident hemolysis in human blood	385:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	1	36	dep	Ca2+	183:186	arg1	SA-CZ					217:221	SA-CZ	217:221	SA-CZ	217:221	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	1	36	dep	Ca2+	183:186	arg1	hydrogel					207:214	composite hydrogel	197:214	composite hydrogel (SA-CZ)	197:222	We developed, characterized, and examined the hemostatic potential of sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ).					
36876801	2	37	from	index	369:373	arg1	blood					415:419	human blood	409:419	human blood	409:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	3	38	theme	bleeding	450:457	arg1	time					459:462	bleeding time	450:462	bleeding time (≈60 %)	450:470	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	38	theme	bleeding	450:457	arg1	%					469:469	≈60 %	465:469	≈60 %	465:469	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	2	39	theme	human	409:413	arg1	blood					415:419	human blood	409:419	human blood	409:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	4	40	theme	post-wound	752:761	arg1	creation					763:770	the 7th-day post-wound creation in-vivo	740:778	the 7th-day post-wound creation in-vivo (p < 0.005)	740:790	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	40	theme	post-wound	752:761	arg1	p < 0.005					781:789	p < 0.005	781:789	p < 0.005	781:789	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	5	41	theme	vital	938:942	arg1	organ					944:948	any vital organ	934:948	any vital organ	934:948	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	2	42	theme	coagulation	322:332	arg1	time					334:337	coagulation time	322:337	coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood	322:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	5	43	theme	non-considerable	901:916	arg1	accumulation					918:929	non-considerable accumulation	901:929	non-considerable accumulation in any vital organ	901:948	Subcutaneous implantation and intra-venous gamma-scintigraphy of hydrogel revealed ample body clearance and non-considerable accumulation in any vital organ, proving its non-thromboembolic nature.					
36876801	3	44	theme	mice	547:550	arg1	p ≤ 0.001					570:578	p ≤ 0.001	570:578	p ≤ 0.001	570:578	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	44	theme	mice	547:550	arg1	model					563:567	the mice hemorrhage model	543:567	the mice hemorrhage model (p ≤ 0.001)	543:579	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	2	45	theme	substantial	247:257	arg1	efficacy					268:275	substantial in-vitro efficacy	247:275	substantial in-vitro efficacy	247:275	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	4	46	theme	enhanced	600:607	arg1	migration					618:626	enhanced cellular migration	600:626	enhanced cellular migration (1.58-fold) in-vitro	600:647	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	46	theme	enhanced	600:607	arg1	1.58-fold					629:637	1.58-fold	629:637	1.58-fold	629:637	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	47	theme	in-vivo	772:778	arg1	creation					763:770	the 7th-day post-wound creation in-vivo	740:778	the 7th-day post-wound creation in-vivo (p < 0.005)	740:790	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	4	47	theme	in-vivo	772:778	arg1	p < 0.005					781:789	p < 0.005	781:789	p < 0.005	781:789	SA-CZ also showed enhanced cellular migration (1.58-fold) in-vitro and improved wound closure (≈70 %) as compared with betadine (≈38 %) and saline (≈34 %) at the 7th-day post-wound creation in-vivo (p < 0.005).					
36876801	3	48	theme	hemorrhage	552:561	arg1	p ≤ 0.001					570:578	p ≤ 0.001	570:578	p ≤ 0.001	570:578	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	48	theme	hemorrhage	552:561	arg1	model					563:567	the mice hemorrhage model	543:567	the mice hemorrhage model (p ≤ 0.001)	543:579	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	49	theme	blood	481:485	arg1	loss					487:490	mean blood loss	476:490	mean blood loss (≈65 %)	476:498	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	3	49	theme	blood	481:485	arg1	%					497:497	≈65 %	493:497	≈65 %	493:497	SA-CZ significantly reduced bleeding time (≈60 %) and mean blood loss (≈65 %) in the tail bleeding and liver incision in the mice hemorrhage model (p ≤ 0.001).					
36876801	2	50	theme	coagulation	357:367	arg1	BCI					376:378	BCI	376:378	BCI	376:378	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	50	theme	coagulation	357:367	arg1	index					369:373	better blood coagulation index	344:373	better blood coagulation index (BCI)	344:379	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	0	51	theme	pre-hospital	51:62	arg1	hemostasis					64:73	pre-hospital hemostasis	51:73	pre-hospital hemostasis	51:73	A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care.					
36876801	2	52	theme	SA-CZ	225:229	arg1	hydrogel					231:238	SA-CZ hydrogel	225:238	SA-CZ hydrogel	225:238	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	53	from	hemolysis	396:404	arg1	blood					415:419	human blood	409:419	human blood	409:419	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	54	theme	blood	351:355	arg1	BCI					376:378	BCI	376:378	BCI	376:378	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36876801	2	54	theme	blood	351:355	arg1	index					369:373	better blood coagulation index	344:373	better blood coagulation index (BCI)	344:379	SA-CZ hydrogel showed substantial in-vitro efficacy, as observed by the significant reduction in coagulation time with better blood coagulation index (BCI) and no evident hemolysis in human blood.					
36113337	3	0	theme	alginate	644:651	arg1	matrix					663:668	sodium alginate polymeric matrix	637:668	sodium alginate polymeric matrix	637:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	8	1	theme	composite	1230:1238	arg1	beads					1240:1244	composite beads	1230:1244	composite beads	1230:1244	Tf2N/PS composite beads.					
36113337	9	2	theme	radiation	1323:1331	arg1	stability					1333:1341	radiation stability	1323:1341	radiation stability	1323:1341	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	7	3	theme	Detail	1126:1131	arg1	study					1133:1137	Detail study	1126:1137	Detail study for the extraction chromatography separation of Cs(I)	1126:1191	Detail study for the extraction chromatography separation of Cs(I) was studied with BOCMC/C8mim.					
36113337	4	4	from	solution	796:803	arg1	liquids					838:844	isodecanol/dodecane and ionic liquids	808:844	isodecanol/dodecane and ionic liquids	808:844	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	4	5	theme	ligand	789:794	arg1	solution					796:803	the ligand solution	785:803	the ligand solution in isodecanol/dodecane and ionic liquids	785:844	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	1	6	theme	selective	168:176	arg1	ligand					178:183	a selective ligand	166:183	a selective ligand for Cs(I) cation	166:200	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	1	6	theme	selective	168:176	arg1	Bis-octyloxy-calix[4					115:134	Bis-octyloxy-calix[4]arene-mono-crown-6	115:153	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC)	115:161	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	1	7	theme	solvent	224:230	arg1	method					243:248	solvent extraction method	224:248	solvent extraction method	224:248	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	5	8	theme	desired	921:927	arg1	quality					929:935	the desired quality	917:935	the desired quality of beads in PES and sodium alginate matrix	917:978	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	4	9	theme	isodecanol/dodecane	808:826	arg1	liquids					838:844	isodecanol/dodecane and ionic liquids	808:844	isodecanol/dodecane and ionic liquids	808:844	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	6	10	theme	ligand	1050:1055	arg1	solution					1057:1064	25 mM ligand solution	1044:1064	25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid	1044:1101	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	1	11	theme	extraction	232:241	arg1	method					243:248	solvent extraction method	224:248	solvent extraction method	224:248	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	0	12	theme	radio-cesium	90:101	arg1	separation					103:112	radio-cesium separation	90:112	radio-cesium separation	90:112	Stability of composite polymeric beads containing a calix[4]arene-mono-crown-6 ligand for radio-cesium separation.					
36113337	9	13	dep	preparation	1276:1286	arg1	the					1272:1274	the	1272:1274	the	1272:1274	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	1	14	from	feed	281:284	arg1	separation					258:267	its separation	254:267	its separation from acidic feed	254:284	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	7	15	theme	extraction	1147:1156	arg1	separation					1173:1182	the extraction chromatography separation	1143:1182	the extraction chromatography separation of Cs(I)	1143:1191	Detail study for the extraction chromatography separation of Cs(I) was studied with BOCMC/C8mim.					
36113337	6	16	theme	liquid	1096:1101	arg1	C8mim.Tf2N					1079:1088	C8mim.Tf2N ionic liquid	1079:1101	C8mim.Tf2N ionic liquid	1079:1101	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	5	17	from	quality	929:935	arg1	matrix					973:978	sodium alginate matrix	957:978	sodium alginate matrix	957:978	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	5	17	from	quality	929:935	arg1	PES					949:951	PES	949:951	PES	949:951	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	6	18	theme	good	995:998	arg1	quality					1000:1006	very good quality	990:1006	very good quality	990:1006	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	6	19	theme	ionic	1090:1094	arg1	C8mim.Tf2N					1079:1088	C8mim.Tf2N ionic liquid	1079:1101	C8mim.Tf2N ionic liquid	1079:1101	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	1	20	theme	Cs	189:190	arg1	cation					195:200	Cs(I) cation	189:200	Cs(I) cation	189:200	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	6	21	theme	PS	1115:1116	arg1	matrix					1118:1123	PS matrix	1115:1123	PS matrix	1115:1123	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	3	22	theme	polymeric	653:661	arg1	matrix					663:668	sodium alginate polymeric matrix	637:668	sodium alginate polymeric matrix	637:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	9	23	from	investigations	1254:1267	arg1	reusability					1307:1317	reusability	1307:1317	reusability	1307:1317	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	23	from	investigations	1254:1267	arg1	stability					1333:1341	radiation stability	1323:1341	radiation stability	1323:1341	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	23	from	investigations	1254:1267	arg1	characterization					1289:1304	characterization	1289:1304	characterization	1289:1304	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	23	from	investigations	1254:1267	arg1	preparation					1276:1286	preparation	1276:1286	preparation	1276:1286	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	2	24	theme	method	370:375	arg1	ease					325:328	ease	325:328	ease of extraction chromatography separation method	325:375	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	24	theme	method	370:375	arg1	advantages					310:319	the various advantages	298:319	the various advantages	298:319	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	25	theme	composite	416:424	arg1	beads					426:430	stable composite beads	409:430	stable composite beads containing BOCMC entrapped in a suitable polymeric matrix	409:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	26	contain	containing	432:441	arg2	BOCMC					443:447	BOCMC	443:447	BOCMC entrapped in a suitable polymeric matrix	443:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	26	contain	containing	432:441	arg1	beads					426:430	stable composite beads	409:430	stable composite beads containing BOCMC entrapped in a suitable polymeric matrix	409:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	27	theme	separation	359:368	arg1	method					370:375	extraction chromatography separation method	333:375	extraction chromatography separation method	333:375	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	28	theme	stable	409:414	arg1	beads					426:430	stable composite beads	409:430	stable composite beads containing BOCMC entrapped in a suitable polymeric matrix	409:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	5	29	theme	sodium	957:962	arg1	matrix					973:978	sodium alginate matrix	957:978	sodium alginate matrix	957:978	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	2	30	theme	chromatography	344:357	arg1	method					370:375	extraction chromatography separation method	333:375	extraction chromatography separation method	333:375	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	0	31	theme	polymeric	23:31	arg1	beads					33:37	composite polymeric beads	13:37	composite polymeric beads	13:37	Stability of composite polymeric beads containing a calix[4]arene-mono-crown-6 ligand for radio-cesium separation.					
36113337	9	32	theme	beads	1352:1356	arg1	reusability					1307:1317	reusability	1307:1317	reusability	1307:1317	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	32	theme	beads	1352:1356	arg1	stability					1333:1341	radiation stability	1323:1341	radiation stability	1323:1341	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	32	theme	beads	1352:1356	arg1	characterization					1289:1304	characterization	1289:1304	characterization	1289:1304	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	9	32	theme	beads	1352:1356	arg1	preparation					1276:1286	preparation	1276:1286	preparation	1276:1286	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	5	33	theme	beads	940:944	arg1	quality					929:935	the desired quality	917:935	the desired quality of beads in PES and sodium alginate matrix	917:978	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	0	34	theme	composite	13:21	arg1	beads					33:37	composite polymeric beads	13:37	composite polymeric beads	13:37	Stability of composite polymeric beads containing a calix[4]arene-mono-crown-6 ligand for radio-cesium separation.					
36113337	9	35	theme	Detail	1247:1252	arg1	investigations					1254:1267	Detail investigations	1247:1267	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads	1247:1356	Detail investigations on the preparation, characterization, reusability and radiation stability of these beads have been studied and reported in details.					
36113337	4	36	theme	beads	691:695	arg1	Preparations					671:682	Preparations	671:682	Preparations of the beads	671:695	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	7	37	theme	chromatography	1158:1171	arg1	separation					1173:1182	the extraction chromatography separation	1143:1182	the extraction chromatography separation of Cs(I)	1143:1191	Detail study for the extraction chromatography separation of Cs(I) was studied with BOCMC/C8mim.					
36113337	3	38	from	BOCMC	582:586	arg1	matrix					663:668	sodium alginate polymeric matrix	637:668	sodium alginate polymeric matrix	637:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	38	from	BOCMC	582:586	arg1	PES					628:630	PES	628:630	PES	628:630	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	38	from	BOCMC	582:586	arg1	PS					604:605	PS	604:605	PS	604:605	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	38	from	BOCMC	582:586	arg1	sulfone					619:625	polyether sulfone	609:625	polyether sulfone (PES)	609:631	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	38	from	BOCMC	582:586	arg1	polysulfone					591:601	polysulfone	591:601	polysulfone (PS)	591:606	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	0	39	theme	arene-mono-crown-6	60:77	arg1	ligand					79:84	a calix[4]arene-mono-crown-6 ligand	50:84	a calix[4]arene-mono-crown-6 ligand for radio-cesium separation	50:112	Stability of composite polymeric beads containing a calix[4]arene-mono-crown-6 ligand for radio-cesium separation.					
36113337	3	40	theme	polymeric	555:563	arg1	beads					565:569	composite polymeric beads	545:569	composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix	545:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	0	41	theme	beads	33:37	arg1	Stability					0:8	Stability	0:8	Stability of composite polymeric beads	0:37	Stability of composite polymeric beads containing a calix[4]arene-mono-crown-6 ligand for radio-cesium separation.					
36113337	1	42	theme	acidic	274:279	arg1	feed					281:284	acidic feed	274:284	acidic feed	274:284	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	3	43	theme	beads	565:569	arg1	series					535:540	a series	533:540	a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix	533:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	4	44	theme	ionic	832:836	arg1	liquids					838:844	isodecanol/dodecane and ionic liquids	808:844	isodecanol/dodecane and ionic liquids	808:844	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	6	45	theme	25 mM	1044:1048	arg1	solution					1057:1064	25 mM ligand solution	1044:1064	25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid	1044:1101	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	1	46	used	used	216:219	arg2	Bis-octyloxy-calix[4					115:134	Bis-octyloxy-calix[4]arene-mono-crown-6	115:153	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC)	115:161	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	1	46	used	used	216:219	arg2	ligand					178:183	a selective ligand	166:183	a selective ligand for Cs(I) cation	166:200	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	1	46	used	used	216:219	arg2	BOCMC					156:160	BOCMC	156:160	BOCMC	156:160	Bis-octyloxy-calix[4]arene-mono-crown-6 (BOCMC) is a selective ligand for Cs(I) cation, and has been used in solvent extraction method for its separation from acidic feed.					
36113337	3	47	theme	composite	545:553	arg1	beads					565:569	composite polymeric beads	545:569	composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix	545:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	2	48	theme	various	302:308	arg1	advantages					310:319	the various advantages	298:319	the various advantages	298:319	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	6	49	used	used	1107:1110	arg2	solution					1057:1064	25 mM ligand solution	1044:1064	25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid	1044:1101	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	4	50	dep	attempted	702:710	arg1	using					779:783	using	779:783	using the ligand solution in isodecanol/dodecane and ionic liquids	779:844	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	4	50	dep	attempted	702:710	arg1	dissolving					715:724	dissolving	715:724	dissolving the solid BOCMC in the polymer solution	715:764	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	5	51	theme	alginate	964:971	arg1	matrix					973:978	sodium alginate matrix	957:978	sodium alginate matrix	957:978	Every attempt failed to get the desired quality of beads in PES and sodium alginate matrix.					
36113337	4	52	theme	polymer	749:755	arg1	solution					757:764	the polymer solution	745:764	the polymer solution	745:764	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	3	53	theme	polyether	609:617	arg1	sulfone					619:625	polyether sulfone	609:625	polyether sulfone (PES)	609:631	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	53	theme	polyether	609:617	arg1	PES					628:630	PES	628:630	PES	628:630	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	4	54	theme	solid	730:734	arg1	BOCMC					736:740	the solid BOCMC	726:740	the solid BOCMC in the polymer solution	726:764	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	7	55	theme	Cs	1187:1188	arg1	separation					1173:1182	the extraction chromatography separation	1143:1182	the extraction chromatography separation of Cs(I)	1143:1191	Detail study for the extraction chromatography separation of Cs(I) was studied with BOCMC/C8mim.					
36113337	3	56	contain	containing	571:580	arg2	BOCMC					582:586	BOCMC	582:586	BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix	582:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	3	56	contain	containing	571:580	arg1	beads					565:569	composite polymeric beads	545:569	composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix	545:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	2	57	theme	polymeric	473:481	arg1	matrix					483:488	a suitable polymeric matrix	462:488	a suitable polymeric matrix	462:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	58	theme	extraction	333:342	arg1	method					370:375	extraction chromatography separation method	333:375	extraction chromatography separation method	333:375	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	2	59	theme	suitable	464:471	arg1	matrix					483:488	a suitable polymeric matrix	462:488	a suitable polymeric matrix	462:488	Looking at the various advantages and ease of extraction chromatography separation method, an attempt was made to prepare stable composite beads containing BOCMC entrapped in a suitable polymeric matrix.					
36113337	3	60	theme	sodium	637:642	arg1	matrix					663:668	sodium alginate polymeric matrix	637:668	sodium alginate polymeric matrix	637:668	Therefore, an attempt was made to prepare a series of composite polymeric beads containing BOCMC in polysulfone (PS), polyether sulfone (PES) and sodium alginate polymeric matrix.					
36113337	4	61	from	BOCMC	736:740	arg1	solution					757:764	the polymer solution	745:764	the polymer solution	745:764	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36113337	6	62	theme	stable	1012:1017	arg1	beads					1019:1023	stable beads	1012:1023	stable beads	1012:1023	However, very good quality and stable beads were obtained when 25 mM ligand solution dissolved in C8mim.Tf2N ionic liquid was used in PS matrix.					
36113337	4	63	theme	polymeric	869:877	arg1	solution					879:886	the polymeric solution	865:886	the polymeric solution	865:886	Preparations of the beads were attempted by dissolving the solid BOCMC in the polymer solution, and also by using the ligand solution in isodecanol/dodecane and ionic liquids and then mixing in the polymeric solution.					
36162465	5	0	theme	radical	841:847	arg1	pathways					864:871	both radical and nonradical pathways	836:871	both radical and nonradical pathways	836:871	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	4	1	theme	Co-g-C3N4-2	554:564	arg1	microsphere					566:576	as-prepared Co-g-C3N4-2 microsphere	542:576	as-prepared Co-g-C3N4-2 microsphere	542:576	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	7	2	theme	weak	1197:1200	arg1	influence					1202:1210	weak influence	1197:1210	weak influence	1197:1210	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	3	theme	Proposed	1051:1058	arg1	system					1088:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	1	4	theme	difficult	180:188	arg1	separation					190:199	difficult separation	180:199	difficult separation	180:199	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	4	5	theme	TC	661:662	arg1	degradation					646:656	the degradation	642:656	the degradation of TC	642:662	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	6	6	theme	major	971:975	arg1	species					993:999	major reactive oxygen species	971:999	major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system	971:1048	Meanwhile, SO4•-, OH•, O2•- and 1O2 were major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system.					
36162465	4	7	theme	excellent	588:596	arg1	performance					608:618	excellent catalytic performance	588:618	excellent catalytic performance in PMS activation for the degradation of TC	588:662	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	2	8	theme	feasible	397:404	arg1	method					406:411	a feasible method	395:411	a feasible method	395:411	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	5	9	theme	calcium	737:743	arg1	microspheres					754:765	the calcium alginate microspheres	733:765	the calcium alginate microspheres	733:765	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	5	10	theme	activation	673:682	arg1	mechanisms					684:693	the activation mechanisms	669:693	the activation mechanisms of PMS over Co-g-C3N4-2 microspheres	669:730	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	2	11	theme	calcium	314:320	arg1	microspheres					365:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	9	12	from	catalysis	1531:1539	arg1	activation					1555:1564	persulfate activation	1544:1564	persulfate activation	1544:1564	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	5	13	theme	alginate	745:752	arg1	microspheres					754:765	the calcium alginate microspheres	733:765	the calcium alginate microspheres	733:765	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	9	14	theme	persulfate	1544:1553	arg1	activation					1555:1564	persulfate activation	1544:1564	persulfate activation	1544:1564	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	8	15	theme	metal	1358:1362	arg1	ion					1364:1366	metal ion	1358:1366	metal ion	1358:1366	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	0	16	theme	organic	135:141	arg1	pollutants					143:152	organic pollutants	135:152	organic pollutants	135:152	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	5	17	theme	PMS	698:700	arg1	mechanisms					684:693	the activation mechanisms	669:693	the activation mechanisms of PMS over Co-g-C3N4-2 microspheres	669:730	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	8	18	from	catalyst	1373:1380	arg1	release					1347:1353	the release	1343:1353	the release of metal ion from catalyst	1343:1380	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	3	19	theme	surface	477:483	arg1	area					485:488	its specific surface area	464:488	its specific surface area	464:488	Notably, embedding Co ion into g-C3N4 can improve its specific surface area and electrochemical activities.					
36162465	8	20	theme	microspheres	1313:1324	arg1	construction					1285:1296	the construction	1281:1296	the construction of Co-g-C3N4-2 microspheres	1281:1324	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	4	21	theme	as-prepared	542:552	arg1	microsphere					566:576	as-prepared Co-g-C3N4-2 microsphere	542:576	as-prepared Co-g-C3N4-2 microsphere	542:576	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	7	22	theme	co-existing	1174:1184	arg1	anions					1186:1191	co-existing anions	1174:1191	co-existing anions	1174:1191	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	23	theme	pH	1160:1161	arg1	range					1163:1167	a wide pH range	1153:1167	a wide pH range	1153:1167	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	24	theme	microsphere/PMS	1072:1086	arg1	system					1088:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	9	25	theme	heterogeneous	1517:1529	arg1	catalysis					1531:1539	heterogeneous catalysis	1517:1539	heterogeneous catalysis in persulfate activation	1517:1564	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	3	26	theme	Co	433:434	arg1	ion					436:438	embedding Co ion	423:438	embedding Co ion into g-C3N4	423:450	Notably, embedding Co ion into g-C3N4 can improve its specific surface area and electrochemical activities.					
36162465	5	27	theme	Co-g-C3N4-2	707:717	arg1	microspheres					719:730	Co-g-C3N4-2 microspheres	707:730	Co-g-C3N4-2 microspheres	707:730	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	9	28	theme	catalysis	1531:1539	arg1	application					1502:1512	the application	1498:1512	the application of heterogeneous catalysis in persulfate activation for wastewater treatment	1498:1589	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	2	29	theme	composite	355:363	arg1	microspheres					365:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	3	30	theme	specific	468:475	arg1	area					485:488	its specific surface area	464:488	its specific surface area	464:488	Notably, embedding Co ion into g-C3N4 can improve its specific surface area and electrochemical activities.					
36162465	0	31	theme	Co-g-C3N4	33:41	arg1	microspheres					53:64	Co-g-C3N4 composite microspheres	33:64	Co-g-C3N4 composite microspheres	33:64	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	0	31	theme	Co-g-C3N4	33:41	arg1	mediator					82:89	an efficient mediator	69:89	an efficient mediator to activate peroxymonosulfate for degrading organic pollutants	69:152	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	6	32	theme	microsphere/PMS	1027:1041	arg1	system					1043:1048	the Co-g-C3N4-2 microsphere/PMS system	1011:1048	the Co-g-C3N4-2 microsphere/PMS system	1011:1048	Meanwhile, SO4•-, OH•, O2•- and 1O2 were major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system.					
36162465	5	33	theme	direct	785:790	arg1	transfer					801:808	the direct electron transfer	781:808	the direct electron transfer between TC and PMS	781:827	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	2	34	theme	Co-g-C3N4-2	343:353	arg1	microspheres					365:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	5	35	theme	PMS	908:910	arg1	activation					894:903	the activation	890:903	the activation of PMS over Co-g-C3N4-2	890:927	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	3	36	theme	embedding	423:431	arg1	ion					436:438	embedding Co ion	423:438	embedding Co ion into g-C3N4	423:450	Notably, embedding Co ion into g-C3N4 can improve its specific surface area and electrochemical activities.					
36162465	6	37	theme	Co-g-C3N4-2	1015:1025	arg1	system					1043:1048	the Co-g-C3N4-2 microsphere/PMS system	1011:1048	the Co-g-C3N4-2 microsphere/PMS system	1011:1048	Meanwhile, SO4•-, OH•, O2•- and 1O2 were major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system.					
36162465	5	38	theme	electron	792:799	arg1	transfer					801:808	the direct electron transfer	781:808	the direct electron transfer between TC and PMS	781:827	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	2	39	theme	alginate-immobilized	322:341	arg1	microspheres					365:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres	310:376	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	1	40	theme	Co-based	237:244	arg1	catalysts					246:254	Co-based catalysts	237:254	Co-based catalysts	237:254	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	5	41	theme	nonradical	853:862	arg1	pathways					864:871	both radical and nonradical pathways	836:871	both radical and nonradical pathways	836:871	For the activation mechanisms of PMS over Co-g-C3N4-2 microspheres, the calcium alginate microspheres could mediate the direct electron transfer between TC and PMS, while both radical and nonradical pathways were involved in the activation of PMS over Co-g-C3N4-2.					
36162465	9	42	from	application	1502:1512	arg1	activation					1555:1564	persulfate activation	1544:1564	persulfate activation	1544:1564	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	1	43	theme	catalysts	246:254	arg1	application					222:232	the application	218:232	the application of Co-based catalysts in persulfate activation	218:279	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	0	44	theme	composite	43:51	arg1	microspheres					53:64	Co-g-C3N4 composite microspheres	33:64	Co-g-C3N4 composite microspheres	33:64	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	0	44	theme	composite	43:51	arg1	mediator					82:89	an efficient mediator	69:89	an efficient mediator to activate peroxymonosulfate for degrading organic pollutants	69:152	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	9	45	theme	current	1453:1459	arg1	work					1461:1464	current work	1453:1464	current work	1453:1464	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	7	46	theme	Co-g-C3N4-2	1235:1245	arg1	system					1263:1268	Co-g-C3N4-2 microsphere/PMS system	1235:1268	Co-g-C3N4-2 microsphere/PMS system	1235:1268	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	3	47	theme	electrochemical	494:508	arg1	activities					510:519	electrochemical activities	494:519	electrochemical activities	494:519	Notably, embedding Co ion into g-C3N4 can improve its specific surface area and electrochemical activities.					
36162465	4	48	from	performance	608:618	arg1	activation					627:636	PMS activation	623:636	PMS activation	623:636	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	4	49	theme	catalytic	598:606	arg1	performance					608:618	excellent catalytic performance	588:618	excellent catalytic performance in PMS activation for the degradation of TC	588:662	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	7	50	theme	great	1111:1115	arg1	ability					1129:1135	great degradation ability	1111:1135	great degradation ability	1111:1135	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	51	theme	TC	1215:1216	arg1	degradation					1218:1228	TC degradation	1215:1228	TC degradation	1215:1228	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	4	52	theme	PMS	623:625	arg1	activation					627:636	PMS activation	623:636	PMS activation	623:636	More significantly, as-prepared Co-g-C3N4-2 microsphere presented excellent catalytic performance in PMS activation for the degradation of TC.					
36162465	7	53	theme	wide	1155:1158	arg1	range					1163:1167	a wide pH range	1153:1167	a wide pH range	1153:1167	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	8	54	theme	Co-g-C3N4-2	1301:1311	arg1	microspheres					1313:1324	Co-g-C3N4-2 microspheres	1301:1324	Co-g-C3N4-2 microspheres	1301:1324	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	6	55	theme	oxygen	986:991	arg1	species					993:999	major reactive oxygen species	971:999	major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system	971:1048	Meanwhile, SO4•-, OH•, O2•- and 1O2 were major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	56	theme	degradation	1117:1127	arg1	ability					1129:1135	great degradation ability	1111:1135	great degradation ability	1111:1135	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	2	57	theme	first	298:302	arg1	time					304:307	the first time	294:307	the first time	294:307	Herein, for the first time, the calcium alginate-immobilized Co-g-C3N4-2 composite microspheres were prepared by a feasible method.					
36162465	9	58	from	activation	1555:1564	arg1	application					1502:1512	the application	1498:1512	the application of heterogeneous catalysis in persulfate activation for wastewater treatment	1498:1589	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	1	59	theme	Poor	155:158	arg1	stability					166:174	Poor water stability	155:174	Poor water stability	155:174	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	1	60	theme	persulfate	259:268	arg1	activation					270:279	persulfate activation	259:279	persulfate activation	259:279	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	8	61	theme	catalyst	1433:1440	arg1	recovery					1421:1428	the recovery	1417:1428	the recovery of catalyst	1417:1440	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	7	62	theme	Co-g-C3N4-2	1060:1070	arg1	system					1088:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system	1051:1093	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	1	63	theme	water	160:164	arg1	stability					166:174	Poor water stability	155:174	Poor water stability	155:174	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	9	64	theme	wastewater	1570:1579	arg1	treatment					1581:1589	wastewater treatment	1570:1589	wastewater treatment	1570:1589	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36162465	8	65	theme	ion	1364:1366	arg1	release					1347:1353	the release	1343:1353	the release of metal ion from catalyst	1343:1380	Moreover, the construction of Co-g-C3N4-2 microspheres not only avoided the release of metal ion from catalyst, but also provided convenience for the recovery of catalyst.					
36162465	1	66	from	application	222:232	arg1	activation					270:279	persulfate activation	259:279	persulfate activation	259:279	Poor water stability and difficult separation severely limited the application of Co-based catalysts in persulfate activation.					
36162465	0	67	theme	efficient	72:80	arg1	microspheres					53:64	Co-g-C3N4 composite microspheres	33:64	Co-g-C3N4 composite microspheres	33:64	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	0	67	theme	efficient	72:80	arg1	mediator					82:89	an efficient mediator	69:89	an efficient mediator to activate peroxymonosulfate for degrading organic pollutants	69:152	The calcium alginate-immobilized Co-g-C3N4 composite microspheres as an efficient mediator to activate peroxymonosulfate for degrading organic pollutants.					
36162465	6	68	theme	reactive	977:984	arg1	species					993:999	major reactive oxygen species	971:999	major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system	971:1048	Meanwhile, SO4•-, OH•, O2•- and 1O2 were major reactive oxygen species formed in the Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	69	theme	microsphere/PMS	1247:1261	arg1	system					1263:1268	Co-g-C3N4-2 microsphere/PMS system	1235:1268	Co-g-C3N4-2 microsphere/PMS system	1235:1268	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	70	contain	had	1193:1195	arg2	influence					1202:1210	weak influence	1197:1210	weak influence	1197:1210	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	7	70	contain	had	1193:1195	arg1	anions					1186:1191	co-existing anions	1174:1191	co-existing anions	1174:1191	Proposed Co-g-C3N4-2 microsphere/PMS system still exhibited great degradation ability towards TC over a wide pH range, and co-existing anions had weak influence on TC degradation over Co-g-C3N4-2 microsphere/PMS system.					
36162465	9	71	theme	novel	1478:1482	arg1	insights					1484:1491	some novel insights	1473:1491	some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment	1473:1589	In short, current work shared some novel insights into the application of heterogeneous catalysis in persulfate activation for wastewater treatment.					
36701091	5	0	theme	decamer	823:829	arg1	unit					831:834	the CS-specific MC decamer unit	804:834	the CS-specific MC decamer unit with VA complex	804:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	8	1	dep	potential	1378:1386	arg1	therapeutic					1388:1398	therapeutic	1388:1398	therapeutic	1388:1398	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	6	2	theme	transcription	927:939	arg1	Runx2					907:911	Runx2	907:911	Runx2 (runt-related transcription factor 2)	907:949	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	2	theme	transcription	927:939	arg1	factor					941:946	runt-related transcription factor 2	914:948	runt-related transcription factor 2	914:948	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	1	3	theme	material	193:200	arg1	sites					216:220	surgical sites	207:220	surgical sites for autografts in bone defects treatment	207:261	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	1	3	theme	material	193:200	arg1	limitations					172:182	The limitations	168:182	The limitations of graft material	168:200	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	1	3	theme	material	193:200	arg1	material					193:200	graft material	187:200	graft material	187:200	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	1	4	theme	significant	277:287	arg1	challenge					289:297	a significant challenge	275:297	a significant challenge in bone tissue engineering	275:324	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	0	5	theme	Osteogenic	111:120	arg1	Biocompatibility					0:15	Biocompatibility	0:15	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	0:79	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	0	5	theme	Osteogenic	111:120	arg1	Efficiency					122:131	Osteogenic Efficiency	111:131	Osteogenic Efficiency with In Silico Molecular Modeling	111:165	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	0	6	with	Efficiency	122:131	arg1	Modeling					158:165	In Silico Molecular Modeling	138:165	In Silico Molecular Modeling	138:165	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	2	7	theme	signaling	403:411	arg1	pathways					413:420	the osteogenic signaling pathways	388:420	the osteogenic signaling pathways	388:420	Phytocompounds markedly affect bone metabolism by activating the osteogenic signaling pathways.					
36701091	0	8	theme	In	138:139	arg1	Modeling					158:165	In Silico Molecular Modeling	138:165	In Silico Molecular Modeling	138:165	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	3	9	theme	restorative	620:630	arg1	agent					632:636	a restorative agent	618:636	a restorative agent for bone defect treatment	618:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	8	10	theme	bone	1423:1426	arg1	regeneration					1428:1439	bone regeneration	1423:1439	bone regeneration	1423:1439	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	7	11	theme	stem	1168:1171	arg1	cells					1173:1177	the mouse mesenchymal stem cells	1146:1177	the mouse mesenchymal stem cells	1146:1177	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	4	12	theme	hydrogels	760:768	arg1	formation					705:713	the formation	701:713	the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA)	701:779	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	1	13	theme	bone	302:305	arg1	engineering					314:324	bone tissue engineering	302:324	bone tissue engineering	302:324	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	0	14	theme	Molecular	148:156	arg1	Modeling					158:165	In Silico Molecular Modeling	138:165	In Silico Molecular Modeling	138:165	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	0	15	dep	In	138:139	arg1	Silico					141:146	Silico	141:146	Silico	141:146	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	4	16	theme	CS/MC	718:722	arg1	hydrogels					724:732	CS/MC hydrogels	718:732	CS/MC hydrogels	718:732	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	6	17	theme	binding	1013:1019	arg1	affinity					1021:1028	a high binding affinity	1006:1028	a high binding affinity towards the functional site of the Runx2 protein	1006:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	7	18	theme	mouse	1150:1154	arg1	cells					1173:1177	the mouse mesenchymal stem cells	1146:1177	the mouse mesenchymal stem cells	1146:1177	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	7	19	theme	stem	1232:1235	arg1	cells					1237:1241	the stem cells	1228:1241	the stem cells	1228:1241	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	1	20	theme	surgical	207:214	arg1	sites					216:220	surgical sites	207:220	surgical sites for autografts in bone defects treatment	207:261	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	1	20	theme	surgical	207:214	arg1	material					193:200	graft material	187:200	graft material	187:200	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	3	21	theme	present	427:433	arg1	study					435:439	The present study	423:439	The present study	423:439	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	6	22	theme	high	1008:1011	arg1	affinity					1021:1028	a high binding affinity	1006:1028	a high binding affinity towards the functional site of the Runx2 protein	1006:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	23	with	mechanism	976:984	arg1	VA					991:992	VA	991:992	VA	991:992	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	3	24	theme	thermo-responsive	496:512	arg1	hydrogels					514:522	the bio-composite thermo-responsive hydrogels	478:522	the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment	478:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	5	25	theme	stable	864:869	arg1	integration					871:881	a stable integration	862:881	a stable integration	862:881	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	1	26	theme	tissue	307:312	arg1	engineering					314:324	bone tissue engineering	302:324	bone tissue engineering	302:324	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	2	27	theme	bone	358:361	arg1	metabolism					363:372	bone metabolism	358:372	bone metabolism	358:372	Phytocompounds markedly affect bone metabolism by activating the osteogenic signaling pathways.					
36701091	3	28	theme	hydrogels	514:522	arg1	biocompatibility					458:473	the biocompatibility	454:473	the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment	454:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	0	29	theme	Acid-Encapsulated	29:45	arg1	Hydrogel					72:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	0	30	theme	Veratric	20:27	arg1	Hydrogel					72:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	3	31	theme	veratric	596:603	arg1	VA					611:612	VA	611:612	VA	611:612	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	3	31	theme	veratric	596:603	arg1	acid					605:608	veratric acid	596:608	veratric acid (VA)	596:613	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	6	32	theme	runt-related	914:925	arg1	Runx2					907:911	Runx2	907:911	Runx2 (runt-related transcription factor 2)	907:949	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	32	theme	runt-related	914:925	arg1	factor					941:946	runt-related transcription factor 2	914:948	runt-related transcription factor 2	914:948	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	4	33	theme	CS/MC	754:758	arg1	CS/MC-VA					771:778	CS/MC-VA	771:778	CS/MC-VA	771:778	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	4	33	theme	CS/MC	754:758	arg1	hydrogels					760:768	VA encapsulated CS/MC hydrogels	738:768	VA encapsulated CS/MC hydrogels (CS/MC-VA)	738:779	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	7	34	theme	osteogenic	1198:1207	arg1	differentiation					1209:1223	osteogenic differentiation	1198:1223	osteogenic differentiation	1198:1223	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	0	35	theme	Hydrogel	72:79	arg1	Biocompatibility					0:15	Biocompatibility	0:15	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	0:79	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	0	35	theme	Hydrogel	72:79	arg1	Efficiency					122:131	Osteogenic Efficiency	111:131	Osteogenic Efficiency with In Silico Molecular Modeling	111:165	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	8	36	theme	study	1331:1335	arg1	results					1337:1343	The study results	1327:1343	The study results	1327:1343	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	7	37	theme	formulated	1084:1093	arg1	hydrogels					1104:1112	The formulated CS/MC-VA hydrogels	1080:1112	The formulated CS/MC-VA hydrogels	1080:1112	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	6	38	theme	protein	1071:1077	arg1	site					1053:1056	the functional site	1038:1056	the functional site of the Runx2 protein	1038:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	38	theme	protein	1071:1077	arg1	protein					1071:1077	the Runx2 protein	1061:1077	the Runx2 protein	1061:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	3	39	theme	bone	642:645	arg1	treatment					654:662	bone defect treatment	642:662	bone defect treatment	642:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	4	40	theme	hydrogels	724:732	arg1	formation					705:713	the formation	701:713	the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA)	701:779	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	1	41	theme	bone	240:243	arg1	defects					245:251	bone defects	240:251	bone defects treatment	240:261	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	0	42	theme	Chitosan/Methylcellulose	47:70	arg1	Hydrogel					72:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel	20:79	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	1	43	from	challenge	289:297	arg1	engineering					314:324	bone tissue engineering	302:324	bone tissue engineering	302:324	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	3	44	theme	defect	647:652	arg1	treatment					654:662	bone defect treatment	642:662	bone defect treatment	642:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	1	45	theme	defects	245:251	arg1	treatment					253:261	bone defects treatment	240:261	bone defects treatment	240:261	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	0	46	theme	Biological	82:91	arg1	Characterization					93:108	Biological Characterization	82:108	Biological Characterization	82:108	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	5	47	theme	Molecular	782:790	arg1	analysis					792:799	Molecular analysis	782:799	Molecular analysis of the CS-specific MC decamer unit with VA complex	782:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	6	48	theme	Runx2	1065:1069	arg1	protein					1071:1077	the Runx2 protein	1061:1077	the Runx2 protein	1061:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	7	49	theme	phosphate	1274:1282	arg1	deposition					1284:1293	calcium phosphate deposition	1266:1293	calcium phosphate deposition	1266:1293	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	2	50	theme	osteogenic	392:401	arg1	pathways					413:420	the osteogenic signaling pathways	388:420	the osteogenic signaling pathways	388:420	Phytocompounds markedly affect bone metabolism by activating the osteogenic signaling pathways.					
36701091	7	51	theme	CS/MC-VA	1095:1102	arg1	hydrogels					1104:1112	The formulated CS/MC-VA hydrogels	1080:1112	The formulated CS/MC-VA hydrogels	1080:1112	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	7	52	theme	calcium	1266:1272	arg1	deposition					1284:1293	calcium phosphate deposition	1266:1293	calcium phosphate deposition	1266:1293	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	1	53	from	autografts	226:235	arg1	treatment					253:261	bone defects treatment	240:261	bone defects treatment	240:261	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	7	54	theme	mesenchymal	1156:1166	arg1	cells					1173:1177	the mouse mesenchymal stem cells	1146:1177	the mouse mesenchymal stem cells	1146:1177	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	6	55	theme	docking	968:974	arg1	mechanism					976:984	the docking mechanism	964:984	the docking mechanism with VA	964:992	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	5	56	theme	VA	841:842	arg1	complex					844:850	VA complex	841:850	VA complex	841:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	7	57	theme	von	1307:1309	arg1	staining					1317:1324	the von Kossa staining	1303:1324	the von Kossa staining	1303:1324	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	7	58	theme	Kossa	1311:1315	arg1	staining					1317:1324	the von Kossa staining	1303:1324	the von Kossa staining	1303:1324	The formulated CS/MC-VA hydrogels exhibited biocompatibility with the mouse mesenchymal stem cells, while VA promoted osteogenic differentiation in the stem cells, which was verified by calcium phosphate deposition through the von Kossa staining.					
36701091	8	59	theme	alternative	1400:1410	arg1	source					1412:1417	a potential therapeutic alternative source	1376:1417	a potential therapeutic alternative source for bone regeneration	1376:1439	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	8	59	theme	alternative	1400:1410	arg1	CS/MC-VA					1358:1365	CS/MC-VA	1358:1365	CS/MC-VA	1358:1365	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	5	60	with	unit	831:834	arg1	complex					844:850	VA complex	841:850	VA complex	841:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	5	61	theme	unit	831:834	arg1	analysis					792:799	Molecular analysis	782:799	Molecular analysis of the CS-specific MC decamer unit with VA complex	782:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	4	62	theme	VA	738:739	arg1	CS/MC-VA					771:778	CS/MC-VA	771:778	CS/MC-VA	771:778	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	4	62	theme	VA	738:739	arg1	hydrogels					760:768	VA encapsulated CS/MC hydrogels	738:768	VA encapsulated CS/MC hydrogels (CS/MC-VA)	738:779	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	8	63	theme	potential	1378:1386	arg1	source					1412:1417	a potential therapeutic alternative source	1376:1417	a potential therapeutic alternative source for bone regeneration	1376:1439	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	8	63	theme	potential	1378:1386	arg1	CS/MC-VA					1358:1365	CS/MC-VA	1358:1365	CS/MC-VA	1358:1365	The study results suggest that CS/MC-VA could be a potential therapeutic alternative source for bone regeneration.					
36701091	5	64	theme	CS-specific	808:818	arg1	unit					831:834	the CS-specific MC decamer unit	804:834	the CS-specific MC decamer unit with VA complex	804:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	6	65	located	found	955:959	arg2	Runx2					907:911	Runx2	907:911	Runx2 (runt-related transcription factor 2)	907:949	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	65	located	found	955:959	arg1	mechanism					976:984	the docking mechanism	964:984	the docking mechanism with VA	964:992	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	65	located	found	955:959	arg2	factor					941:946	runt-related transcription factor 2	914:948	runt-related transcription factor 2	914:948	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	4	66	theme	encapsulated	741:752	arg1	CS/MC-VA					771:778	CS/MC-VA	771:778	CS/MC-VA	771:778	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	4	66	theme	encapsulated	741:752	arg1	hydrogels					760:768	VA encapsulated CS/MC hydrogels	738:768	VA encapsulated CS/MC hydrogels (CS/MC-VA)	738:779	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	4	67	theme	spectroscopy	669:680	arg1	analyses					682:689	The spectroscopy analyses	665:689	The spectroscopy analyses	665:689	The spectroscopy analyses confirmed the formation of CS/MC hydrogels and VA encapsulated CS/MC hydrogels (CS/MC-VA).					
36701091	5	68	theme	MC	820:821	arg1	unit					831:834	the CS-specific MC decamer unit	804:834	the CS-specific MC decamer unit with VA complex	804:850	Molecular analysis of the CS-specific MC decamer unit with VA complex exhibited a stable integration in the system.					
36701091	3	69	theme	bio-composite	482:494	arg1	hydrogels					514:522	the bio-composite thermo-responsive hydrogels	478:522	the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment	478:662	The present study investigated the biocompatibility of the bio-composite thermo-responsive hydrogels consisting of chitosan (CS), and methylcellulose (MC) encapsulated with veratric acid (VA) as a restorative agent for bone defect treatment.					
36701091	0	70	dep	Biocompatibility	0:15	arg1	Characterization					93:108	Biological Characterization	82:108	Biological Characterization	82:108	Biocompatibility of Veratric Acid-Encapsulated Chitosan/Methylcellulose Hydrogel: Biological Characterization, Osteogenic Efficiency with In Silico Molecular Modeling.					
36701091	1	71	theme	graft	187:191	arg1	material					193:200	graft material	187:200	graft material	187:200	The limitations of graft material, and surgical sites for autografts in bone defects treatment have become a significant challenge in bone tissue engineering.					
36701091	6	72	theme	functional	1042:1051	arg1	site					1053:1056	the functional site	1038:1056	the functional site of the Runx2 protein	1038:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36701091	6	72	theme	functional	1042:1051	arg1	protein					1071:1077	the Runx2 protein	1061:1077	the Runx2 protein	1061:1077	Further, Runx2 (runt-related transcription factor 2) was found in the docking mechanism with VA, indicating a high binding affinity towards the functional site of the Runx2 protein.					
36394277	4	0	theme	chitosan/borosilicate	579:599	arg1	scaffolds					610:618	the chitosan/borosilicate bioglass scaffolds	575:618	the chitosan/borosilicate bioglass scaffolds	575:618	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	2	1	with	scaffolds	251:259	arg1	activity					280:287	antimicrobial activity	266:287	antimicrobial activity	266:287	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	2	1	with	scaffolds	251:259	arg1	properties					308:317	osteoinductive properties	293:317	osteoinductive properties	293:317	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	4	2	theme	Zinc	688:691	arg1	scaffolds					693:701	the oxidized Zinc scaffolds	675:701	the oxidized Zinc scaffolds	675:701	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	3	theme	oxidized	679:686	arg1	scaffolds					693:701	the oxidized Zinc scaffolds	675:701	the oxidized Zinc scaffolds	675:701	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	0	4	theme	bone	125:128	arg1	regeneration					130:141	bone regeneration	125:141	bone regeneration	125:141	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	3	5	theme	composite	429:437	arg1	scaffolds					439:447	chitosan composite scaffolds	420:447	chitosan composite scaffolds	420:447	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	1	6	theme	significant	205:215	arg1	challenge					226:234	a significant clinical challenge	203:234	a significant clinical challenge	203:234	The treatment of implant-associated bone infection remains a significant clinical challenge.					
36394277	1	7	theme	clinical	217:224	arg1	challenge					226:234	a significant clinical challenge	203:234	a significant clinical challenge	203:234	The treatment of implant-associated bone infection remains a significant clinical challenge.					
36394277	0	8	theme	ZnO	0:2	arg1	nanoparticle					4:15	ZnO nanoparticle	0:15	ZnO nanoparticle	0:15	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	0	9	theme	chitosan/borosilicate	26:46	arg1	scaffold					67:74	chitosan/borosilicate bioglass composite scaffold	26:74	chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration	26:141	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	2	10	theme	clinical	360:367	arg1	outcomes					369:376	clinical outcomes	360:376	clinical outcomes	360:376	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	1	11	theme	bone	180:183	arg1	infection					185:193	implant-associated bone infection	161:193	implant-associated bone infection	161:193	The treatment of implant-associated bone infection remains a significant clinical challenge.					
36394277	0	12	theme	composite	57:65	arg1	scaffold					67:74	chitosan/borosilicate bioglass composite scaffold	26:74	chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration	26:141	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	0	13	theme	bioglass	48:55	arg1	scaffold					67:74	chitosan/borosilicate bioglass composite scaffold	26:74	chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration	26:141	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	4	14	theme	vitro</i>and<i>in	525:541	arg1	vivo</i>experiments					543:561	<i>In vitro</i>and<i>in vivo</i>experiments	519:561	<i>In vitro</i>and<i>in vivo</i>experiments	519:561	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	15	contain	have	703:706	arg1	scaffolds					693:701	the oxidized Zinc scaffolds	675:701	the oxidized Zinc scaffolds	675:701	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	15	contain	have	703:706	arg2	properties					729:738	better antibacterial properties	708:738	better antibacterial properties	708:738	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	3	16	theme	chitosan	420:427	arg1	scaffolds					439:447	chitosan composite scaffolds	420:447	chitosan composite scaffolds	420:447	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	4	17	theme	<i>In	519:523	arg1	vivo</i>experiments					543:561	<i>In vitro</i>and<i>in vivo</i>experiments	519:561	<i>In vitro</i>and<i>in vivo</i>experiments	519:561	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	2	18	theme	antimicrobial	266:278	arg1	activity					280:287	antimicrobial activity	266:287	antimicrobial activity	266:287	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	4	19	theme	osteogenic	646:655	arg1	properties					657:666	osteogenic properties	646:666	osteogenic properties	646:666	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	1	20	theme	infection	185:193	arg1	treatment					148:156	The treatment	144:156	The treatment of implant-associated bone infection	144:193	The treatment of implant-associated bone infection remains a significant clinical challenge.					
36394277	2	21	theme	bone	246:249	arg1	scaffolds					251:259	bone scaffolds	246:259	bone scaffolds with antimicrobial activity and osteoinductive properties	246:317	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	4	22	theme	antibacterial	715:727	arg1	properties					729:738	better antibacterial properties	708:738	better antibacterial properties	708:738	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	1	23	theme	implant-associated	161:178	arg1	infection					185:193	implant-associated bone infection	161:193	implant-associated bone infection	161:193	The treatment of implant-associated bone infection remains a significant clinical challenge.					
36394277	4	24	theme	better	708:713	arg1	properties					729:738	better antibacterial properties	708:738	better antibacterial properties	708:738	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	0	25	theme	bacterial	91:99	arg1	infection					101:109	bacterial infection	91:109	bacterial infection	91:109	ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration.					
36394277	3	26	mod	modified	489:496	arg3	oxide					513:517	nano-zinc oxide	503:517	nano-zinc oxide	503:517	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	3	26	mod	modified	489:496	arg1	surface					477:483	then the surface	468:483	then the surface	468:483	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	3	27	theme	nano-zinc	503:511	arg1	oxide					513:517	nano-zinc oxide	503:517	nano-zinc oxide	503:517	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	3	28	theme	borosilicate	394:405	arg1	bioglass					407:414	borosilicate bioglass	394:414	borosilicate bioglass	394:414	In this study, borosilicate bioglass and chitosan composite scaffolds were prepared, and then the surface was modified with nano-zinc oxide.					
36394277	4	29	theme	bioglass	601:608	arg1	scaffolds					610:618	the chitosan/borosilicate bioglass scaffolds	575:618	the chitosan/borosilicate bioglass scaffolds	575:618	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	2	30	theme	osteoinductive	293:306	arg1	properties					308:317	osteoinductive properties	293:317	osteoinductive properties	293:317	However, bone scaffolds with antimicrobial activity and osteoinductive properties can prevent these infections and improve clinical outcomes.					
36394277	4	31	contain	have	620:623	arg1	scaffolds					610:618	the chitosan/borosilicate bioglass scaffolds	575:618	the chitosan/borosilicate bioglass scaffolds	575:618	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	31	contain	have	620:623	arg2	properties					657:666	osteogenic properties	646:666	osteogenic properties	646:666	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	31	contain	have	620:623	arg2	degradation					630:640	good degradation	625:640	good degradation	625:640	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36394277	4	32	theme	good	625:628	arg1	degradation					630:640	good degradation	625:640	good degradation	625:640	<i>In vitro</i>and<i>in vivo</i>experiments showed that the chitosan/borosilicate bioglass scaffolds have good degradation and osteogenic properties, while the oxidized Zinc scaffolds have better antibacterial properties.					
36075525	0	0	theme	peripheral	105:114	arg1	injuries					122:129	peripheral nerve injuries	105:129	peripheral nerve injuries	105:129	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	10	1	from	studies	1386:1392	arg1	cells					1405:1409	Schwann cells	1397:1409	Schwann cells	1397:1409	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	5	2	theme	different	746:754	arg1	concentrations					759:772	different SP concentrations	746:772	different SP concentrations	746:772	Different ALG concentrations and viscosity grades and different SP concentrations were considered.					
36075525	6	3	theme	Experiments	887:897	arg1	Design					877:882	a Design	875:882	a Design of Experiments (DoE) approach (full factorial design)	875:936	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	9	4	theme	nanogel	1254:1260	arg1	dispersion					1262:1271	nanogel dispersion	1254:1271	nanogel dispersion	1254:1271	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	5	5	theme	Different	692:700	arg1	concentrations					706:719	Different ALG concentrations	692:719	Different ALG concentrations	692:719	Different ALG concentrations and viscosity grades and different SP concentrations were considered.					
36075525	0	6	from	tool	97:100	arg1	injuries					122:129	peripheral nerve injuries	105:129	peripheral nerve injuries	105:129	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	3	7	theme	antioxidant	529:539	arg1	compound					563:570	antioxidant and anti-inflammatory compound	529:570	antioxidant and anti-inflammatory compound	529:570	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	10	8	dep	in	1377:1378	arg1	vitro					1380:1384	vitro	1380:1384	vitro	1380:1384	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	0	9	theme	nerve	116:120	arg1	injuries					122:129	peripheral nerve injuries	105:129	peripheral nerve injuries	105:129	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	8	10	dep	Infrared	1097:1104	arg1	FTIR					1107:1110	FTIR	1107:1110	FTIR	1107:1110	Fourier Transform Infrared (FTIR) measurements performed on nanogels of optimal composition confirmed SP-ALG interaction.					
36075525	2	11	from	recovery	249:256	arg1	patients					261:268	patients	261:268	patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	261:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	7	12	theme	profilometry	1052:1063	arg1	measurements					1065:1076	rheological and profilometry measurements	1036:1076	rheological and profilometry measurements	1036:1076	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	9	13	theme	employment	1303:1312	arg1	view					1291:1294	view	1291:1294	view of the employment of freeze-drying process	1291:1337	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	5	14	theme	SP	756:757	arg1	concentrations					759:772	different SP concentrations	746:772	different SP concentrations	746:772	Different ALG concentrations and viscosity grades and different SP concentrations were considered.					
36075525	4	15	theme	ionic	616:620	arg1	interaction					622:632	the ionic interaction	612:632	the ionic interaction between ALG and SP	612:651	In particular, micro/nanogels based on the ionic interaction between ALG and SP were obtained via ionotropic gelation.					
36075525	8	16	theme	composition	1159:1169	arg1	nanogels					1139:1146	nanogels	1139:1146	nanogels of optimal composition	1139:1169	Fourier Transform Infrared (FTIR) measurements performed on nanogels of optimal composition confirmed SP-ALG interaction.					
36075525	7	17	theme	rheological	1036:1046	arg1	measurements					1065:1076	rheological and profilometry measurements	1036:1076	rheological and profilometry measurements	1036:1076	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	10	18	theme	Schwann	1397:1403	arg1	cells					1405:1409	Schwann cells	1397:1409	Schwann cells	1397:1409	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	2	19	theme	debilitating	329:340	arg1	pathologies					342:352	the most debilitating pathologies	320:352	the most debilitating pathologies	320:352	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	20	theme	clinical	380:387	arg1	challenge					389:397	a major clinical challenge	372:397	a major clinical challenge	372:397	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	20	theme	clinical	380:387	arg1	development					195:205	The development	191:205	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	191:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	8	21	theme	optimal	1151:1157	arg1	composition					1159:1169	optimal composition	1151:1169	optimal composition	1151:1169	Fourier Transform Infrared (FTIR) measurements performed on nanogels of optimal composition confirmed SP-ALG interaction.					
36075525	9	22	theme	freeze-drying	1317:1329	arg1	process					1331:1337	freeze-drying process	1317:1337	freeze-drying process	1317:1337	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	10	23	theme	SP	1433:1434	arg1	ability					1422:1428	the ability	1418:1428	the ability of SP of expressing antioxidant and anti-inflammatory properties	1418:1493	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	2	24	theme	most	324:327	arg1	pathologies					342:352	the most debilitating pathologies	320:352	the most debilitating pathologies	320:352	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	25	theme	major	374:378	arg1	challenge					389:397	a major clinical challenge	372:397	a major clinical challenge	372:397	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	25	theme	major	374:378	arg1	development					195:205	The development	191:205	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	191:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	8	26	theme	SP-ALG	1181:1186	arg1	interaction					1188:1198	SP-ALG interaction	1181:1198	SP-ALG interaction	1181:1198	Fourier Transform Infrared (FTIR) measurements performed on nanogels of optimal composition confirmed SP-ALG interaction.					
36075525	9	27	theme	process	1331:1337	arg1	employment					1303:1312	the employment	1299:1312	the employment of freeze-drying process	1299:1337	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	9	28	theme	trehalose	1217:1225	arg1	addition					1205:1212	The addition	1201:1212	The addition of trehalose as cryoprotectant agent to nanogel dispersion	1201:1271	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	0	29	theme	alginate-spermidine	15:33	arg1	Development					0:10	Development	0:10	Development of alginate-spermidine	0:33	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	10	30	theme	properties	1484:1493	arg1	ability					1422:1428	the ability	1418:1428	the ability of SP of expressing antioxidant and anti-inflammatory properties	1418:1493	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	6	31	dep	approach	905:912	arg1	design					930:935	full factorial design	915:935	full factorial design	915:935	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	1	32	theme	Formulation	132:142	arg1	studies					144:150	Formulation studies	132:150	Formulation studies	132:150	Formulation studies and physico-chemical characterization.					
36075525	0	33	theme	potential	53:61	arg1	tool					97:100	potential antioxidant and anti-inflammatory tool	53:100	potential antioxidant and anti-inflammatory tool in peripheral nerve injuries	53:129	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	6	34	theme	factorial	920:928	arg1	design					930:935	full factorial design	915:935	full factorial design	915:935	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	10	35	theme	anti-inflammatory	1466:1482	arg1	properties					1484:1493	expressing antioxidant and anti-inflammatory properties	1439:1493	properties	1484:1493	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	2	36	theme	strategy	223:230	arg1	challenge					389:397	a major clinical challenge	372:397	a major clinical challenge	372:397	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	36	theme	strategy	223:230	arg1	development					195:205	The development	191:205	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	191:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	3	37	theme	anti-inflammatory	545:561	arg1	compound					563:570	antioxidant and anti-inflammatory compound	529:570	antioxidant and anti-inflammatory compound	529:570	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	6	38	from	influence	795:803	arg1	size					841:844	micro/nanogels size	826:844	micro/nanogels size	826:844	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	3	39	theme	endogenous	428:437	arg1	polyamine					439:447	an endogenous polyamine	425:447	an endogenous polyamine	425:447	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	3	39	theme	endogenous	428:437	arg1	spermidine					408:417	spermidine	408:417	spermidine (SP)	408:422	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	6	40	theme	full	915:918	arg1	design					930:935	full factorial design	915:935	full factorial design	915:935	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	2	41	theme	successful	212:221	arg1	strategy					223:230	a successful strategy	210:230	a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	210:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	10	42	theme	nanogels	1533:1540	arg1	formation					1520:1528	the formation	1516:1528	the formation of nanogels	1516:1540	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	9	43	theme	stable	1351:1356	arg1	product					1358:1364	a stable product	1349:1364	a stable product	1349:1364	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	9	44	theme	cryoprotectant	1230:1243	arg1	agent					1245:1249	cryoprotectant agent	1230:1249	cryoprotectant agent	1230:1249	The addition of trehalose as cryoprotectant agent to nanogel dispersion was considered in view of the employment of freeze-drying process to obtain a stable product.					
36075525	0	45	dep	potential	53:61	arg1	antioxidant					63:73	antioxidant	63:73	antioxidant	63:73	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	7	46	theme	Scanning	985:992	arg1	SEM					1015:1017	SEM	1015:1017	SEM	1015:1017	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	7	46	theme	Scanning	985:992	arg1	Microscope					1003:1012	Scanning Electron Microscope	985:1012	Scanning Electron Microscope (SEM) analysis	985:1027	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	4	47	theme	ionotropic	671:680	arg1	gelation					682:689	ionotropic gelation	671:689	ionotropic gelation	671:689	In particular, micro/nanogels based on the ionic interaction between ALG and SP were obtained via ionotropic gelation.					
36075525	6	48	theme	micro/nanogels	826:839	arg1	size					841:844	micro/nanogels size	826:844	micro/nanogels size	826:844	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	3	49	theme	dual	469:472	arg1	role					474:477	a dual role	467:477	a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound	467:570	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	7	50	theme	Electron	994:1001	arg1	SEM					1015:1017	SEM	1015:1017	SEM	1015:1017	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	7	50	theme	Electron	994:1001	arg1	Microscope					1003:1012	Scanning Electron Microscope	985:1012	Scanning Electron Microscope (SEM) analysis	985:1027	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	2	51	theme	full	244:247	arg1	recovery					249:256	a full recovery	242:256	a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies,	242:353	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	10	52	theme	in	1377:1378	arg1	studies					1386:1392	in vitro studies	1377:1392	in vitro studies on Schwann cells	1377:1409	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	1	53	theme	physico-chemical	156:171	arg1	characterization					173:188	physico-chemical characterization	156:188	physico-chemical characterization	156:188	Formulation studies and physico-chemical characterization.					
36075525	7	54	theme	Microscope	1003:1012	arg1	analysis					1020:1027	Scanning Electron Microscope (SEM) analysis	985:1027	Scanning Electron Microscope (SEM) analysis	985:1027	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	6	55	theme	variables	813:821	arg1	influence					795:803	The influence	791:803	The influence of such variables on micro/nanogels size	791:844	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	10	56	theme	antioxidant	1450:1460	arg1	ability					1422:1428	the ability	1418:1428	the ability of SP of expressing antioxidant and anti-inflammatory properties	1418:1493	Moreover, in vitro studies on Schwann cells proved the ability of SP of expressing antioxidant and anti-inflammatory properties, even if involved in the formation of nanogels.					
36075525	2	57	theme	pathologies	342:352	arg1	pathologies					342:352	the most debilitating pathologies	320:352	the most debilitating pathologies	320:352	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	57	theme	pathologies	342:352	arg1	one					313:315	one	313:315	one	313:315	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	57	theme	pathologies	342:352	arg1	injury					299:304	peripheral nerve injury	282:304	peripheral nerve injury (PNI)	282:310	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	5	58	theme	viscosity	725:733	arg1	grades					735:740	viscosity grades	725:740	viscosity grades	725:740	Different ALG concentrations and viscosity grades and different SP concentrations were considered.					
36075525	6	59	theme	such	808:811	arg1	variables					813:821	such variables	808:821	such variables	808:821	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	2	60	theme	nerve	293:297	arg1	PNI					307:309	PNI	307:309	PNI	307:309	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	60	theme	nerve	293:297	arg1	one					313:315	one	313:315	one	313:315	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	60	theme	nerve	293:297	arg1	injury					299:304	peripheral nerve injury	282:304	peripheral nerve injury (PNI)	282:310	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	60	theme	nerve	293:297	arg1	pathologies					342:352	the most debilitating pathologies	320:352	the most debilitating pathologies	320:352	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	7	61	theme	micro/nanogels	956:969	arg1	formation					943:951	The formation	939:951	The formation of micro/nanogels	939:969	The formation of micro/nanogels was proved by Scanning Electron Microscope (SEM) analysis and by rheological and profilometry measurements.					
36075525	0	62	theme	anti-inflammatory	79:95	arg1	tool					97:100	potential antioxidant and anti-inflammatory tool	53:100	potential antioxidant and anti-inflammatory tool in peripheral nerve injuries	53:129	Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries.					
36075525	6	63	theme	DoE	900:902	arg1	Experiments					887:897	Experiments	887:897	Experiments (DoE) approach (full factorial design)	887:936	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	6	63	theme	DoE	900:902	arg1	approach					905:912	DoE) approach	900:912	DoE) approach	900:912	The influence of such variables on micro/nanogels size was investigated by means of a Design of Experiments (DoE) approach (full factorial design).					
36075525	2	64	theme	peripheral	282:291	arg1	PNI					307:309	PNI	307:309	PNI	307:309	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	64	theme	peripheral	282:291	arg1	one					313:315	one	313:315	one	313:315	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	64	theme	peripheral	282:291	arg1	injury					299:304	peripheral nerve injury	282:304	peripheral nerve injury (PNI)	282:310	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	2	64	theme	peripheral	282:291	arg1	pathologies					342:352	the most debilitating pathologies	320:352	the most debilitating pathologies	320:352	The development of a successful strategy to ensure a full recovery in patients affected by peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major clinical challenge.					
36075525	3	65	theme	cross-linking	483:495	arg1	agent					497:501	cross-linking agent	483:501	cross-linking agent for alginate (ALG)	483:520	Herein, spermidine (SP), an endogenous polyamine, is employed with a dual role: as cross-linking agent for alginate (ALG) and as antioxidant and anti-inflammatory compound.					
36075525	5	66	theme	ALG	702:704	arg1	concentrations					706:719	Different ALG concentrations	692:719	Different ALG concentrations	692:719	Different ALG concentrations and viscosity grades and different SP concentrations were considered.					
35696780	4	0	theme	surface	693:699	arg1	%					731:731	91.6 %	726:731	91.6 %	726:731	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	4	0	theme	surface	693:699	arg1	area					701:704	The porosity and specific surface area	667:704	The porosity and specific surface area of the support	667:719	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	0	1	theme	3D	88:89	arg1	polymer					91:97	a novel 3D polymer	80:97	a novel 3D polymer	80:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	1	2	theme	epoxy	158:162	arg1	resin					164:168	epoxy resin	158:168	epoxy resin in ethanol solution in the macropores of a melamine sponge	158:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	2	3	theme	nonporous	326:334	arg1	morphology					336:345	nonporous morphology	326:345	nonporous morphology	326:345	The produced polymer gel could uniformly deposit on the surface of melamine in either porous or nonporous morphology.					
35696780	3	4	theme	adsorption	536:545	arg1	method					526:531	method	526:531	method of adsorption and crosslinking	526:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	5	from	circulans	508:516	arg1	β-galactosidase					478:492	β-galactosidase	478:492	β-galactosidase from Bacillus circulans	478:516	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	5	from	circulans	508:516	arg1	immobilization					460:473	the immobilization	456:473	the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	456:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	5	6	theme	optimal	846:852	arg1	conditions					869:878	the optimal immobilization conditions	842:878	the optimal immobilization conditions	842:878	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	4	7	theme	specific	684:691	arg1	%					731:731	91.6 %	726:731	91.6 %	726:731	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	4	7	theme	specific	684:691	arg1	area					701:704	The porosity and specific surface area	667:704	The porosity and specific surface area of the support	667:719	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	0	8	from	β-galactosidase	61:75	arg1	polymer					91:97	a novel 3D polymer	80:97	a novel 3D polymer	80:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	1	9	from	curing	148:153	arg1	solution					181:188	ethanol solution	173:188	ethanol solution	173:188	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	1	9	from	curing	148:153	arg1	macropores					197:206	the macropores	193:206	the macropores of a melamine sponge	193:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	1	10	theme	resin	164:168	arg1	curing					148:153	curing	148:153	curing of epoxy resin in ethanol solution in the macropores of a melamine sponge	148:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	3	11	theme	porous	374:379	arg1	coating					381:387	porous coating	374:387	porous coating	374:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	5	12	theme	immobilization	854:867	arg1	conditions					869:878	the optimal immobilization conditions	842:878	the optimal immobilization conditions	842:878	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	8	13	theme	original	1225:1232	arg1	activity					1234:1241	the original activity	1221:1241	the original activity	1221:1241	After 10 cycles, the immobilized β-galactosidase retained 70 % of the original activity.					
35696780	8	14	theme	immobilized	1176:1186	arg1	β-galactosidase					1188:1202	the immobilized β-galactosidase	1172:1202	the immobilized β-galactosidase	1172:1202	After 10 cycles, the immobilized β-galactosidase retained 70 % of the original activity.					
35696780	3	15	from	immobilization	460:473	arg1	circulans					508:516	Bacillus circulans	499:516	Bacillus circulans	499:516	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	2	16	theme	melamine	297:304	arg1	surface					286:292	the surface	282:292	the surface of melamine	282:304	The produced polymer gel could uniformly deposit on the surface of melamine in either porous or nonporous morphology.					
35696780	1	17	theme	ethanol	173:179	arg1	solution					181:188	ethanol solution	173:188	ethanol solution	173:188	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	0	18	theme	Efficient	0:8	arg1	synthesis					10:18	Efficient synthesis	0:18	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer	0:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	3	19	with	sponge	362:367	arg1	coating					381:387	porous coating	374:387	porous coating	374:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	0	20	theme	N-acetyllactosamine	23:41	arg1	synthesis					10:18	Efficient synthesis	0:18	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer	0:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	5	21	theme	specific	787:794	arg1	41.2 mg/gsupport					885:900	41.2 mg/gsupport	885:900	41.2 mg/gsupport	885:900	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	21	theme	specific	787:794	arg1	activity					796:803	the specific activity	783:803	the specific activity of immobilized β-galactosidase under the optimal immobilization conditions	783:878	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	3	22	theme	crosslinking	551:562	arg1	method					526:531	method	526:531	method of adsorption and crosslinking	526:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	5	23	theme	immobilized	808:818	arg1	β-galactosidase					820:834	immobilized β-galactosidase	808:834	immobilized β-galactosidase	808:834	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	8	24	theme	activity	1234:1241	arg1	activity					1234:1241	the original activity	1221:1241	the original activity	1221:1241	After 10 cycles, the immobilized β-galactosidase retained 70 % of the original activity.					
35696780	8	24	theme	activity	1234:1241	arg1	%					1216:1216	70 %	1213:1216	70 % of the original activity	1213:1241	After 10 cycles, the immobilized β-galactosidase retained 70 % of the original activity.					
35696780	6	25	theme	N-acetylglucosamine	993:1011	arg1	biosynthesis					945:956	the biosynthesis	941:956	the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine	941:1011	In the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine were used as donor and acceptor, respectively.					
35696780	1	26	theme	novel	110:114	arg1	support					124:130	A novel polymer support	108:130	A novel polymer support	108:130	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	5	27	theme	β-galactosidase	820:834	arg1	amount					772:777	The loading amount	760:777	The loading amount	760:777	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	27	theme	β-galactosidase	820:834	arg1	41.2 mg/gsupport					885:900	41.2 mg/gsupport	885:900	41.2 mg/gsupport	885:900	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	27	theme	β-galactosidase	820:834	arg1	activity					796:803	the specific activity	783:803	the specific activity of immobilized β-galactosidase under the optimal immobilization conditions	783:878	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	27	theme	β-galactosidase	820:834	arg1	β-galactosidase					820:834	immobilized β-galactosidase	808:834	immobilized β-galactosidase	808:834	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	0	28	theme	immobilized	49:59	arg1	β-galactosidase					61:75	immobilized β-galactosidase	49:75	immobilized β-galactosidase on a novel 3D polymer	49:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	3	29	theme	sealed	643:648	arg1	way					662:664	a sealed circulation way	641:664	a sealed circulation way	641:664	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	30	theme	well-mass	422:430	arg1	support					444:450	a large-sized and well-mass transferred support	404:450	a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	404:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	30	theme	well-mass	422:430	arg1	sponge					362:367	The composite sponge	348:367	The composite sponge with porous coating	348:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	31	theme	large-sized	406:416	arg1	support					444:450	a large-sized and well-mass transferred support	404:450	a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	404:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	31	theme	large-sized	406:416	arg1	sponge					362:367	The composite sponge	348:367	The composite sponge with porous coating	348:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	5	32	theme	loading	764:770	arg1	amount					772:777	The loading amount	760:777	The loading amount	760:777	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	32	theme	loading	764:770	arg1	41.2 mg/gsupport					885:900	41.2 mg/gsupport	885:900	41.2 mg/gsupport	885:900	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	5	32	theme	loading	764:770	arg1	β-galactosidase					820:834	immobilized β-galactosidase	808:834	immobilized β-galactosidase	808:834	The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/gsupport and 16.5 U/mgprotein, respectively.					
35696780	3	33	theme	N-acetyllactosamine	618:636	arg1	preparation					603:613	the preparation	599:613	the preparation of N-acetyllactosamine	599:636	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	34	theme	composite	352:360	arg1	support					444:450	a large-sized and well-mass transferred support	404:450	a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	404:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	34	theme	composite	352:360	arg1	sponge					362:367	The composite sponge	348:367	The composite sponge with porous coating	348:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	1	35	from	macropores	197:206	arg1	curing					148:153	curing	148:153	curing of epoxy resin in ethanol solution in the macropores of a melamine sponge	148:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	3	36	theme	transferred	432:442	arg1	support					444:450	a large-sized and well-mass transferred support	404:450	a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	404:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	36	theme	transferred	432:442	arg1	sponge					362:367	The composite sponge	348:367	The composite sponge with porous coating	348:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	6	37	theme	N-acetyllactosamine	961:979	arg1	biosynthesis					945:956	the biosynthesis	941:956	the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine	941:1011	In the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine were used as donor and acceptor, respectively.					
35696780	6	38	dep	N-acetyllactosamine	961:979	arg1	lactose					981:987	lactose	981:987	lactose	981:987	In the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine were used as donor and acceptor, respectively.					
35696780	3	39	theme	column	571:576	arg1	reactor					578:584	a column reactor	569:584	a column reactor	569:584	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	7	40	theme	optimized	1066:1074	arg1	conditions					1076:1085	optimized conditions	1066:1085	optimized conditions	1066:1085	Under optimized conditions the N-acetyllactosamine yield reached 54 % within 150 min at 50 °C.					
35696780	1	41	theme	polymer	116:122	arg1	support					124:130	A novel polymer support	108:130	A novel polymer support	108:130	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	7	42	theme	N-acetyllactosamine	1091:1109	arg1	yield					1111:1115	the N-acetyllactosamine yield	1087:1115	the N-acetyllactosamine yield	1087:1115	Under optimized conditions the N-acetyllactosamine yield reached 54 % within 150 min at 50 °C.					
35696780	3	43	theme	β-galactosidase	478:492	arg1	immobilization					460:473	the immobilization	456:473	the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	456:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	44	used	used	396:399	arg2	support					444:450	a large-sized and well-mass transferred support	404:450	a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking	404:562	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	3	44	used	used	396:399	arg2	sponge					362:367	The composite sponge	348:367	The composite sponge with porous coating	348:387	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	4	45	theme	support	713:719	arg1	%					731:731	91.6 %	726:731	91.6 %	726:731	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	4	45	theme	support	713:719	arg1	area					701:704	The porosity and specific surface area	667:704	The porosity and specific surface area of the support	667:719	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	3	46	theme	circulation	650:660	arg1	way					662:664	a sealed circulation way	641:664	a sealed circulation way	641:664	The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way.					
35696780	2	47	theme	polymer	243:249	arg1	gel					251:253	The produced polymer gel	230:253	The produced polymer gel	230:253	The produced polymer gel could uniformly deposit on the surface of melamine in either porous or nonporous morphology.					
35696780	1	48	theme	melamine	213:220	arg1	sponge					222:227	a melamine sponge	211:227	a melamine sponge	211:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	0	49	theme	novel	82:86	arg1	polymer					91:97	a novel 3D polymer	80:97	a novel 3D polymer	80:97	Efficient synthesis of N-acetyllactosamine using immobilized β-galactosidase on a novel 3D polymer support.					
35696780	2	50	theme	produced	234:241	arg1	gel					251:253	The produced polymer gel	230:253	The produced polymer gel	230:253	The produced polymer gel could uniformly deposit on the surface of melamine in either porous or nonporous morphology.					
35696780	1	51	from	solution	181:188	arg1	curing					148:153	curing	148:153	curing of epoxy resin in ethanol solution in the macropores of a melamine sponge	148:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	1	52	theme	sponge	222:227	arg1	macropores					197:206	the macropores	193:206	the macropores of a melamine sponge	193:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	1	53	from	resin	164:168	arg1	solution					181:188	ethanol solution	173:188	ethanol solution	173:188	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	1	53	from	resin	164:168	arg1	macropores					197:206	the macropores	193:206	the macropores of a melamine sponge	193:227	A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge.					
35696780	4	54	theme	porosity	671:678	arg1	%					731:731	91.6 %	726:731	91.6 %	726:731	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
35696780	4	54	theme	porosity	671:678	arg1	area					701:704	The porosity and specific surface area	667:704	The porosity and specific surface area of the support	667:719	The porosity and specific surface area of the support were 91.6 % and 46 m2/g, respectively.					
36662610	0	0	theme	Wounds	93:98	arg1	Healing					73:79	Healing	73:79	Healing of Infected Wounds	73:98	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.					
36662610	5	1	dep	in	820:821	arg1	vivo					823:826	vivo	823:826	vivo	823:826	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	5	2	theme	%	900:900	arg1	rate					916:919	a 95% wound healing rate	896:919	a 95% wound healing rate by day 9	896:928	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	0	3	theme	Infected	84:91	arg1	Wounds					93:98	Infected Wounds	84:98	Infected Wounds	84:98	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.					
36662610	3	4	theme	in	685:686	arg1	degradability					694:706	in vitro degradability	685:706	in vitro degradability	685:706	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	5	theme	ionic	484:488	arg1	cross-linking					490:502	ionic cross-linking	484:502	ionic cross-linking	484:502	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	7	6	theme	collagen	1144:1151	arg1	deposition					1110:1119	the deposition	1106:1119	the deposition of skin appendages and collagen	1106:1151	The dressing promotes wound healing by stimulating the deposition of skin appendages and collagen.					
36662610	3	7	theme	hydrogel	348:355	arg1	system					357:362	This hydrogel system	343:362	This hydrogel system	343:362	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	7	8	theme	appendages	1129:1138	arg1	deposition					1110:1119	the deposition	1106:1119	the deposition of skin appendages and collagen	1106:1151	The dressing promotes wound healing by stimulating the deposition of skin appendages and collagen.					
36662610	2	9	theme	wound	283:287	arg1	dressing					289:296	an antimicrobial wound dressing	266:296	an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C	266:340	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	6	10	theme	antimicrobial	989:1001	arg1	peptides					1003:1010	antimicrobial peptides	989:1010	antimicrobial peptides	989:1010	Tissue staining demonstrated that the hydrogel containing antimicrobial peptides was effective in suppressing inflammation.					
36662610	6	11	contain	containing	978:987	arg2	peptides					1003:1010	antimicrobial peptides	989:1010	antimicrobial peptides	989:1010	Tissue staining demonstrated that the hydrogel containing antimicrobial peptides was effective in suppressing inflammation.					
36662610	6	11	contain	containing	978:987	arg1	effective					1016:1024	effective	1016:1024	effective	1016:1024	Tissue staining demonstrated that the hydrogel containing antimicrobial peptides was effective in suppressing inflammation.					
36662610	6	11	contain	containing	978:987	arg1	hydrogel					969:976	the hydrogel	965:976	the hydrogel containing antimicrobial peptides	965:1010	Tissue staining demonstrated that the hydrogel containing antimicrobial peptides was effective in suppressing inflammation.					
36662610	2	12	theme	antimicrobial	269:281	arg1	dressing					289:296	an antimicrobial wound dressing	266:296	an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C	266:340	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	4	13	theme	antibacterial	727:739	arg1	%					754:754	>98%	751:754	>98%	751:754	Its extraordinary antibacterial efficacy (>98%) was verified by an antibacterial experiment.					
36662610	4	13	theme	antibacterial	727:739	arg1	efficacy					741:748	Its extraordinary antibacterial efficacy	709:748	Its extraordinary antibacterial efficacy (>98%)	709:755	Its extraordinary antibacterial efficacy (>98%) was verified by an antibacterial experiment.					
36662610	8	14	theme	composite	1193:1201	arg1	hydrogels					1203:1211	composite hydrogels	1193:1211	composite hydrogels containing antimicrobial peptides	1193:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	14	theme	composite	1193:1201	arg1	type					1267:1270	a promising new type	1251:1270	a promising new type of dressing to promote the healing of infected wounds	1251:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	4	15	theme	extraordinary	713:725	arg1	%					754:754	>98%	751:754	>98%	751:754	Its extraordinary antibacterial efficacy (>98%) was verified by an antibacterial experiment.					
36662610	4	15	theme	extraordinary	713:725	arg1	efficacy					741:748	Its extraordinary antibacterial efficacy	709:748	Its extraordinary antibacterial efficacy (>98%)	709:755	Its extraordinary antibacterial efficacy (>98%) was verified by an antibacterial experiment.					
36662610	8	16	theme	antimicrobial	1224:1236	arg1	peptides					1238:1245	antimicrobial peptides	1224:1245	antimicrobial peptides	1224:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	5	17	theme	healing-promotion	865:881	arg1	effect					883:888	its healing-promotion effect	861:888	its healing-promotion effect	861:888	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	0	18	theme	Peptide	46:52	arg1	HX-12C					54:59	the Antimicrobial Peptide HX-12C	28:59	the Antimicrobial Peptide HX-12C	28:59	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.					
36662610	8	19	theme	wounds	1319:1324	arg1	healing					1299:1305	the healing	1295:1305	the healing of infected wounds	1295:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	3	20	dep	alginate/gelatin	569:584	arg1	pH.					544:546	pH.	544:546	pH.	544:546	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	20	dep	alginate/gelatin	569:584	arg1	has					619:621	has	619:621	has good mechanical and adhesion properties	619:661	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	2	21	theme	novel	306:310	arg1	HX-12C					335:340	HX-12C	335:340	HX-12C	335:340	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	2	21	theme	novel	306:310	arg1	peptide					326:332	a novel antimicrobial peptide	304:332	a novel antimicrobial peptide	304:332	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	1	22	theme	traditional	176:186	arg1	dressings					188:196	traditional dressings	176:196	traditional dressings	176:196	Bacterial infections of the wound surface can be painful for patients, and traditional dressings do not effectively address this problem.					
36662610	0	23	theme	Hydrogel	0:7	arg1	Complex					9:15	Hydrogel Complex	0:15	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C	0:59	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.					
36662610	3	24	dep	in	685:686	arg1	vitro					688:692	vitro	688:692	vitro	688:692	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	1	25	theme	Bacterial	101:109	arg1	infections					111:120	Bacterial infections	101:120	Bacterial infections of the wound surface	101:141	Bacterial infections of the wound surface can be painful for patients, and traditional dressings do not effectively address this problem.					
36662610	8	26	theme	dressing	1275:1282	arg1	type					1267:1270	a promising new type	1251:1270	a promising new type of dressing to promote the healing of infected wounds	1251:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	26	theme	dressing	1275:1282	arg1	hydrogels					1203:1211	composite hydrogels	1193:1211	composite hydrogels containing antimicrobial peptides	1193:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	5	27	theme	in	820:821	arg1	experiments					828:838	in vivo experiments	820:838	in vivo experiments	820:838	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	7	28	theme	skin	1124:1127	arg1	appendages					1129:1138	skin appendages	1124:1138	skin appendages	1124:1138	The dressing promotes wound healing by stimulating the deposition of skin appendages and collagen.					
36662610	3	29	theme	resulting	552:560	arg1	alginate/gelatin					569:584	The resulting sodium alginate/gelatin	548:584	The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties	548:661	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	5	30	theme	wound	902:906	arg1	rate					916:919	a 95% wound healing rate	896:919	a 95% wound healing rate by day 9	896:928	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	3	31	theme	sodium	401:406	arg1	biomaterials					388:399	the natural biomaterials sodium alginate and gelatin	376:427	the natural biomaterials sodium alginate and gelatin	376:427	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	31	theme	sodium	401:406	arg1	alginate					408:415	sodium alginate	401:415	sodium alginate	401:415	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	8	32	theme	infected	1310:1317	arg1	wounds					1319:1324	infected wounds	1310:1324	infected wounds	1310:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	7	33	theme	wound	1077:1081	arg1	healing					1083:1089	wound healing	1077:1089	wound healing	1077:1089	The dressing promotes wound healing by stimulating the deposition of skin appendages and collagen.					
36662610	3	34	theme	adhesion	643:650	arg1	properties					652:661	good mechanical and adhesion properties	623:661	properties	652:661	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	35	theme	HX-12C-loaded	586:598	arg1	CaAGEAM					610:616	CaAGEAM	610:616	CaAGEAM	610:616	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	35	theme	HX-12C-loaded	586:598	arg1	hydrogel					600:607	HX-12C-loaded hydrogel	586:607	HX-12C-loaded hydrogel (CaAGEAM)	586:617	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	36	theme	calcium	440:446	arg1	carbonate					448:456	calcium carbonate	440:456	calcium carbonate	440:456	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	36	theme	calcium	440:446	arg1	source					463:468	a source	461:468	a source of Ca2+	461:476	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	0	37	theme	Antimicrobial	32:44	arg1	HX-12C					54:59	the Antimicrobial Peptide HX-12C	28:59	the Antimicrobial Peptide HX-12C	28:59	Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.					
36662610	3	38	theme	natural	380:386	arg1	biomaterials					388:399	the natural biomaterials sodium alginate and gelatin	376:427	the natural biomaterials sodium alginate and gelatin	376:427	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	38	theme	natural	380:386	arg1	gelatin					421:427	gelatin	421:427	gelatin	421:427	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	38	theme	natural	380:386	arg1	alginate					408:415	sodium alginate	401:415	sodium alginate	401:415	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	6	39	theme	Tissue	931:936	arg1	staining					938:945	Tissue staining	931:945	Tissue staining	931:945	Tissue staining demonstrated that the hydrogel containing antimicrobial peptides was effective in suppressing inflammation.					
36662610	3	40	theme	sodium	562:567	arg1	alginate/gelatin					569:584	The resulting sodium alginate/gelatin	548:584	The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties	548:661	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	41	theme	Ca2+	473:476	arg1	carbonate					448:456	calcium carbonate	440:456	calcium carbonate	440:456	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	41	theme	Ca2+	473:476	arg1	source					463:468	a source	461:468	a source of Ca2+	461:476	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	8	42	theme	promising	1253:1261	arg1	type					1267:1270	a promising new type	1251:1270	a promising new type of dressing to promote the healing of infected wounds	1251:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	42	theme	promising	1253:1261	arg1	hydrogels					1203:1211	composite hydrogels	1193:1211	composite hydrogels containing antimicrobial peptides	1193:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	3	43	dep	biomaterials	388:399	arg1	biomaterials					388:399	the natural biomaterials sodium alginate and gelatin	376:427	the natural biomaterials sodium alginate and gelatin	376:427	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	43	dep	biomaterials	388:399	arg1	gelatin					421:427	gelatin	421:427	gelatin	421:427	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	43	dep	biomaterials	388:399	arg1	alginate					408:415	sodium alginate	401:415	sodium alginate	401:415	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	1	44	theme	wound	129:133	arg1	surface					135:141	the wound surface	125:141	the wound surface	125:141	Bacterial infections of the wound surface can be painful for patients, and traditional dressings do not effectively address this problem.					
36662610	1	45	theme	surface	135:141	arg1	infections					111:120	Bacterial infections	101:120	Bacterial infections of the wound surface	101:141	Bacterial infections of the wound surface can be painful for patients, and traditional dressings do not effectively address this problem.					
36662610	5	46	theme	healing	908:914	arg1	rate					916:919	a 95% wound healing rate	896:919	a 95% wound healing rate by day 9	896:928	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	4	47	theme	antibacterial	776:788	arg1	experiment					790:799	an antibacterial experiment	773:799	an antibacterial experiment	773:799	Its extraordinary antibacterial efficacy (>98%) was verified by an antibacterial experiment.					
36662610	2	48	theme	antimicrobial	312:324	arg1	HX-12C					335:340	HX-12C	335:340	HX-12C	335:340	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	2	48	theme	antimicrobial	312:324	arg1	peptide					326:332	a novel antimicrobial peptide	304:332	a novel antimicrobial peptide	304:332	In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.					
36662610	3	49	contain	has	619:621	arg1	CaAGEAM					610:616	CaAGEAM	610:616	CaAGEAM	610:616	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	49	contain	has	619:621	arg1	hydrogel					600:607	HX-12C-loaded hydrogel	586:607	HX-12C-loaded hydrogel (CaAGEAM)	586:617	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	49	contain	has	619:621	arg2	properties					652:661	good mechanical and adhesion properties	623:661	properties	652:661	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	3	49	contain	has	619:621	arg2	mechanical					628:637	mechanical	628:637	mechanical	628:637	This hydrogel system is based on the natural biomaterials sodium alginate and gelatin, utilizing calcium carbonate as a source of Ca2+ , and ionic cross-linking is facilitated by lowering the solution pH. The resulting sodium alginate/gelatin HX-12C-loaded hydrogel (CaAGEAM) has good mechanical and adhesion properties, biocompatibility and in vitro degradability.					
36662610	8	50	theme	new	1263:1265	arg1	type					1267:1270	a promising new type	1251:1270	a promising new type of dressing to promote the healing of infected wounds	1251:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	50	theme	new	1263:1265	arg1	hydrogels					1203:1211	composite hydrogels	1193:1211	composite hydrogels containing antimicrobial peptides	1193:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	51	contain	containing	1213:1222	arg1	hydrogels					1203:1211	composite hydrogels	1193:1211	composite hydrogels containing antimicrobial peptides	1193:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	51	contain	containing	1213:1222	arg2	peptides					1238:1245	antimicrobial peptides	1224:1245	antimicrobial peptides	1224:1245	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	8	51	contain	containing	1213:1222	arg1	type					1267:1270	a promising new type	1251:1270	a promising new type of dressing to promote the healing of infected wounds	1251:1324	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
36662610	5	52	theme	95	898:899	arg1	%					900:900	%	900:900	%	900:900	More importantly, in vivo experiments further demonstrated its healing-promotion effect, with a 95% wound healing rate by day 9.					
36662610	8	53	theme	study	1174:1178	arg1	results					1158:1164	The results	1154:1164	The results of this study	1154:1178	The results of this study suggest that composite hydrogels containing antimicrobial peptides are a promising new type of dressing to promote the healing of infected wounds.					
35611952	6	0	theme	mechanical	1123:1132	arg1	mechanism					1134:1142	a mechanical mechanism	1121:1142	a mechanical mechanism	1121:1142	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	5	1	theme	∼90	979:981	arg1	%					982:982	%	982:982	%	982:982	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	0	2	theme	Electroblow	84:94	arg1	Spinning					96:103	Multinozzle Electroblow Spinning	72:103	Multinozzle Electroblow Spinning	72:103	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	4	3	theme	face	870:873	arg1	mask					875:878	protective face mask	859:878	protective face mask for medical use	859:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	1	4	theme	ventilation	173:183	arg1	system					185:190	the ventilation system	169:190	the ventilation system	169:190	Particulate matter damages engines of vehicles when blown into the ventilation system.					
35611952	5	5	theme	great	1049:1053	arg1	resistance					1055:1064	great resistance	1049:1064	great resistance to shock	1049:1073	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	3	6	theme	matter	582:587	arg1	efficiency					556:565	filtration efficiency	545:565	filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3	545:629	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	7	theme	%	782:782	arg1	efficiency					795:804	the 95% filtration efficiency	776:804	the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use	776:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	5	8	theme	min-1	1031:1035	arg1	velocity					1014:1021	airflow velocity	1006:1021	airflow velocity of 32 L min-1	1006:1035	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	3	9	with	efficiency	556:565	arg1	diameter					596:603	a diameter	594:603	a diameter of less than 0.3 μm PM0.3	594:629	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	10	from	standard	806:813	arg1	requirements					842:853	GB 19083-2010 technical requirements	818:853	GB 19083-2010 technical requirements for protective face mask for medical use	818:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	6	11	theme	on-road	1163:1169	arg1	cars					1184:1187	on-road and off-road cars	1163:1187	on-road and off-road cars in the long run	1163:1203	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	3	12	theme	spinning	509:516	arg1	technology					518:527	scalable multinozzle electroblow spinning technology	476:527	scalable multinozzle electroblow spinning technology	476:527	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	13	theme	filtration	733:742	arg1	performance					744:754	superior filtration performance	724:754	superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use	724:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	6	14	theme	long	1196:1199	arg1	run					1201:1203	the long run	1192:1203	the long run	1192:1203	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	4	15	theme	polyurethane	658:669	arg1	transparent					699:709	transparent	699:709	transparent	699:709	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	15	theme	polyurethane	658:669	arg1	membranes					685:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	16	theme	GB	818:819	arg1	requirements					842:853	GB 19083-2010 technical requirements	818:853	GB 19083-2010 technical requirements for protective face mask for medical use	818:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	5	17	contain	possess	1041:1047	arg2	resistance					1055:1064	great resistance	1049:1064	great resistance to shock	1049:1073	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	5	17	contain	possess	1041:1047	arg1	composites					958:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	3	18	theme	pleated	446:452	arg1	board					464:468	pleated cellulose board	446:468	pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly	446:637	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	5	19	theme	%	982:982	arg1	PM0.3					994:998	∼90% ultrafine PM0.3	979:998	∼90% ultrafine PM0.3	979:998	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	4	20	theme	medical	884:890	arg1	use					892:894	medical use	884:894	medical use	884:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	5	21	theme	L	1029:1029	arg1	min-1					1031:1035	32 L min-1	1026:1035	32 L min-1	1026:1035	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	3	22	theme	polyurethane	405:416	arg1	nanofibers					418:427	ultrafine polyurethane nanofibers	395:427	ultrafine polyurethane nanofibers (∼122.8 nm)	395:439	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	3	22	theme	polyurethane	405:416	arg1	nm					437:438	∼122.8 nm	430:438	∼122.8 nm	430:438	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	2	23	dep	diameter	273:280	arg1	microns					298:304	larger than ten microns	282:304	an average diameter larger than ten microns	262:304	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	3	24	theme	ultrafine	395:403	arg1	nanofibers					418:427	ultrafine polyurethane nanofibers	395:427	ultrafine polyurethane nanofibers (∼122.8 nm)	395:439	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	3	24	theme	ultrafine	395:403	arg1	nm					437:438	∼122.8 nm	430:438	∼122.8 nm	430:438	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	25	theme	95	780:781	arg1	%					782:782	%	782:782	%	782:782	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	5	26	theme	thermoplastic	921:933	arg1	composites					958:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	0	27	theme	Mass	0:3	arg1	Production					5:14	Mass Production	0:14	Mass Production of Hierarchically	0:32	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	5	28	theme	lightweight	901:911	arg1	composites					958:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	1	29	theme	Particulate	106:116	arg1	matter					118:123	Particulate matter	106:123	Particulate matter	106:123	Particulate matter damages engines of vehicles when blown into the ventilation system.					
35611952	5	30	theme	polyurethane/cellulose	935:956	arg1	composites					958:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	0	31	theme	Hierarchically	19:32	arg1	Production					5:14	Mass Production	0:14	Mass Production of Hierarchically	0:32	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	2	32	with	board	251:255	arg1	diameter					273:280	an average diameter	262:280	an average diameter larger than ten microns	262:304	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	5	33	theme	airflow	1006:1012	arg1	velocity					1014:1021	airflow velocity	1006:1021	airflow velocity of 32 L min-1	1006:1035	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	2	34	theme	removal	321:327	arg1	efficiency					329:338	low removal efficiency	317:338	low removal efficiency of ultrafine particular matter	317:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	3	35	theme	μm	622:623	arg1	diameter					596:603	a diameter	594:603	a diameter of less than 0.3 μm PM0.3	594:629	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	3	36	theme	scalable	476:483	arg1	technology					518:527	scalable multinozzle electroblow spinning technology	476:527	scalable multinozzle electroblow spinning technology	476:527	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	37	from	requirements	842:853	arg1	standard					806:813	standard	806:813	standard	806:813	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	2	38	theme	engine-intake	206:218	arg1	filter					220:225	Conventional engine-intake filter	193:225	Conventional engine-intake filter	193:225	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	39	theme	low	317:319	arg1	efficiency					329:338	low removal efficiency	317:338	low removal efficiency of ultrafine particular matter	317:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	3	40	theme	multinozzle	485:495	arg1	technology					518:527	scalable multinozzle electroblow spinning technology	476:527	scalable multinozzle electroblow spinning technology	476:527	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	0	41	theme	Engine-Intake	43:55	arg1	Filters					61:67	Engine-Intake Air Filters	43:67	Engine-Intake Air Filters	43:67	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	2	42	contain	has	313:315	arg2	efficiency					329:338	low removal efficiency	317:338	low removal efficiency of ultrafine particular matter	317:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	42	contain	has	313:315	arg1	diameter					273:280	an average diameter	262:280	an average diameter larger than ten microns	262:304	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	43	theme	Conventional	193:204	arg1	filter					220:225	Conventional engine-intake filter	193:225	Conventional engine-intake filter	193:225	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	44	theme	average	265:271	arg1	diameter					273:280	an average diameter	262:280	an average diameter larger than ten microns	262:304	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	4	45	theme	superior	724:731	arg1	performance					744:754	superior filtration performance	724:754	superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use	724:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	5	46	theme	pleated	913:919	arg1	composites					958:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites	897:967	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	4	47	theme	protective	859:868	arg1	mask					875:878	protective face mask	859:878	protective face mask for medical use	859:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	48	theme	nanofiber	675:683	arg1	transparent					699:709	transparent	699:709	transparent	699:709	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	48	theme	nanofiber	675:683	arg1	membranes					685:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	6	49	theme	off-road	1175:1182	arg1	cars					1184:1187	on-road and off-road cars	1163:1187	on-road and off-road cars in the long run	1163:1203	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	5	50	theme	ultrafine	984:992	arg1	PM0.3					994:998	∼90% ultrafine PM0.3	979:998	∼90% ultrafine PM0.3	979:998	The lightweight pleated thermoplastic polyurethane/cellulose composites intercept ∼90% ultrafine PM0.3 under airflow velocity of 32 L min-1 and possess great resistance to shock.					
35611952	0	51	theme	Air	57:59	arg1	Filters					61:67	Engine-Intake Air Filters	43:67	Engine-Intake Air Filters	43:67	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	3	52	theme	electroblow	497:507	arg1	technology					518:527	scalable multinozzle electroblow spinning technology	476:527	scalable multinozzle electroblow spinning technology	476:527	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	2	53	theme	microfiber	240:249	arg1	board					251:255	cellulose microfiber board	230:255	cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter	230:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	54	theme	matter	364:369	arg1	efficiency					329:338	low removal efficiency	317:338	low removal efficiency of ultrafine particular matter	317:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	6	55	used	used	1155:1158	arg2	filters					1106:1112	These hierarchically designed filters	1076:1112	These hierarchically designed filters	1076:1112	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	6	56	from	cars	1184:1187	arg1	run					1201:1203	the long run	1192:1203	the long run	1192:1203	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	2	57	theme	cellulose	230:238	arg1	board					251:255	cellulose microfiber board	230:255	cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter	230:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	4	58	theme	technical	832:840	arg1	requirements					842:853	GB 19083-2010 technical requirements	818:853	GB 19083-2010 technical requirements for protective face mask for medical use	818:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	6	59	theme	designed	1097:1104	arg1	filters					1106:1112	These hierarchically designed filters	1076:1112	These hierarchically designed filters	1076:1112	These hierarchically designed filters follow a mechanical mechanism and can be used in on-road and off-road cars in the long run.					
35611952	1	60	theme	vehicles	144:151	arg1	engines					133:139	engines	133:139	engines of vehicles	133:151	Particulate matter damages engines of vehicles when blown into the ventilation system.					
35611952	4	61	theme	filtration	784:793	arg1	efficiency					795:804	the 95% filtration efficiency	776:804	the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use	776:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	3	62	theme	particulate	570:580	arg1	matter					582:587	particulate matter	570:587	particulate matter	570:587	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	63	theme	standard	806:813	arg1	efficiency					795:804	the 95% filtration efficiency	776:804	the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use	776:894	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	2	64	theme	ultrafine	343:351	arg1	matter					364:369	ultrafine particular matter	343:369	ultrafine particular matter	343:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	2	65	theme	particular	353:362	arg1	matter					364:369	ultrafine particular matter	343:369	ultrafine particular matter	343:369	Conventional engine-intake filter is cellulose microfiber board with an average diameter larger than ten microns, which has low removal efficiency of ultrafine particular matter.					
35611952	0	66	theme	Multinozzle	72:82	arg1	Spinning					96:103	Multinozzle Electroblow Spinning	72:103	Multinozzle Electroblow Spinning	72:103	Mass Production of Hierarchically Designed Engine-Intake Air Filters by Multinozzle Electroblow Spinning.					
35611952	4	67	theme	85A	671:673	arg1	transparent					699:709	transparent	699:709	transparent	699:709	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	67	theme	85A	671:673	arg1	membranes					685:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	3	68	theme	filtration	545:554	arg1	efficiency					556:565	filtration efficiency	545:565	filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3	545:629	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	3	69	theme	cellulose	454:462	arg1	board					464:468	pleated cellulose board	446:468	pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly	446:637	In this work, we apply ultrafine polyurethane nanofibers (∼122.8 nm) onto pleated cellulose board using scalable multinozzle electroblow spinning technology, which improves filtration efficiency of particulate matter with a diameter of less than 0.3 μm PM0.3 greatly.					
35611952	4	70	theme	thermoplastic	644:656	arg1	transparent					699:709	transparent	699:709	transparent	699:709	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
35611952	4	70	theme	thermoplastic	644:656	arg1	membranes					685:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes	640:693	The thermoplastic polyurethane 85A nanofiber membranes are transparent, and display superior filtration performance which meets up with the 95% filtration efficiency standard in GB 19083-2010 technical requirements for protective face mask for medical use.					
36335160	5	0	theme	quantitative	1141:1152	arg1	prediction					1154:1163	the quantitative prediction	1137:1163	the quantitative prediction	1137:1163	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	4	1	theme	tablet	822:827	arg1	samples					829:835	milk tablet samples	817:835	milk tablet samples	817:835	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	6	2	with	sucrose	1421:1427	arg1	values					1466:1471	Q2 values	1463:1471	Q2 values	1463:1471	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	3	with	0.9749	614:619	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	4	theme	square	665:670	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	2	5	theme	lactose	258:264	arg1	contents					266:273	sucrose and lactose contents	246:273	sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy	246:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	3	6	with	0.9987	625:630	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	7	with	lactose	1433:1439	arg1	values					1466:1471	Q2 values	1463:1471	Q2 values	1463:1471	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	2	8	theme	near-infrared	297:309	arg1	spectroscopy					317:328	near-infrared (NIR) spectroscopy	297:328	near-infrared (NIR) spectroscopy	297:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	5	9	theme	piecewise	1021:1029	arg1	PDS					1055:1057	PDS	1055:1057	PDS	1055:1057	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	5	9	theme	piecewise	1021:1029	arg1	standardization					1038:1052	piecewise direct standardization	1021:1052	piecewise direct standardization (PDS)	1021:1058	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	0	10	theme	sugars	26:31	arg1	quantification					8:21	Instant quantification	0:21	Instant quantification of sugars in milk tablets	0:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	6	11	theme	high-performance	1172:1187	arg1	method					1233:1238	a reference method	1221:1238	a reference method	1221:1238	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	11	theme	high-performance	1172:1187	arg1	HPLC					1212:1215	HPLC	1212:1215	HPLC	1212:1215	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	11	theme	high-performance	1172:1187	arg1	chromatography					1196:1209	high-performance liquid chromatography	1172:1209	high-performance liquid chromatography (HPLC)	1172:1216	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	12	theme	NIR-chemometric	1255:1269	arg1	model					1271:1275	the developed NIR-chemometric model	1241:1275	the developed NIR-chemometric model	1241:1275	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	2	13	theme	instant	205:211	arg1	method					223:228	an instant and rapid method	202:228	an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy	202:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	2	14	from	contents	266:273	arg1	tablets					283:289	milk tablets	278:289	milk tablets using near-infrared (NIR) spectroscopy	278:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	4	15	theme	spectral	849:856	arg1	deviations					858:867	spectral deviations	849:867	spectral deviations that dramatically affected the predictive performance of the PLS models	849:939	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	5	16	used	used	1065:1068	arg2	methods					974:980	calibration transfer methods	953:980	calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS)	953:1058	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	2	17	theme	sucrose	246:252	arg1	contents					266:273	sucrose and lactose contents	246:273	sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy	246:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	6	18	theme	0.9411	1487:1492	arg1	values					1466:1471	Q2 values	1463:1471	Q2 values	1463:1471	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	1	19	theme	dairy	132:136	arg1	product					138:144	a popular dairy product	122:144	a popular dairy product in many Asian countries	122:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	1	19	theme	dairy	132:136	arg1	tablets					110:116	Milk tablets	105:116	Milk tablets	105:116	Milk tablets are a popular dairy product in many Asian countries.					
36335160	4	20	theme	PLS	930:932	arg1	models					934:939	the PLS models	926:939	the PLS models	926:939	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	0	21	theme	near-infrared	55:67	arg1	spectroscopy					69:80	near-infrared spectroscopy	55:80	near-infrared spectroscopy	55:80	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	3	22	theme	squares	511:517	arg1	regression					525:534	partial least squares (PLS) regression	497:534	partial least squares (PLS) regression	497:534	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	23	theme	lactose	571:577	arg1	contents					579:586	lactose contents	571:586	lactose contents	571:586	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	24	theme	0.7973	1476:1481	arg1	values					1466:1471	Q2 values	1463:1471	Q2 values	1463:1471	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	1	25	theme	Asian	154:158	arg1	countries					160:168	many Asian countries	149:168	many Asian countries	149:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	3	26	theme	quantitative	339:350	arg1	analysis					352:359	the quantitative analysis	335:359	the quantitative analysis	335:359	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	1	27	from	product	138:144	arg1	countries					160:168	many Asian countries	149:168	many Asian countries	149:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	0	28	from	tablets	41:47	arg1	quantification					8:21	Instant quantification	0:21	Instant quantification of sugars in milk tablets	0:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	0	29	theme	milk	36:39	arg1	tablets					41:47	milk tablets	36:47	milk tablets	36:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	3	30	theme	training	364:371	arg1	set					373:375	a training set	362:375	a training set composed of laboratory-scale milk samples	362:417	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	0	31	theme	Instant	0:6	arg1	quantification					8:21	Instant quantification	0:21	Instant quantification of sugars in milk tablets	0:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	5	32	theme	milk	1110:1113	arg1	samples					1122:1128	the real milk tablet samples	1101:1128	the real milk tablet samples	1101:1128	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	6	33	theme	PDS	1519:1521	arg1	transformation					1523:1536	the PDS transformation	1515:1536	the PDS transformation	1515:1536	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	34	theme	central	444:450	arg1	CCD					470:472	CCD	470:472	CCD	470:472	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	34	theme	central	444:450	arg1	design					462:467	a central composite design	442:467	a central composite design (CCD)	442:473	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	35	theme	mean	1370:1373	arg1	error					1382:1386	root mean square error	1365:1386	root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1365:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	36	theme	laboratory-scale	389:404	arg1	samples					411:417	laboratory-scale milk samples	389:417	laboratory-scale milk samples	389:417	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	37	theme	R2	601:602	arg1	values					604:609	R2 values	601:609	R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	601:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	38	used	used	479:482	arg2	set					373:375	a training set	362:375	a training set composed of laboratory-scale milk samples	362:417	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	39	theme	least	505:509	arg1	squares					511:517	partial least squares	497:517	partial least squares (PLS) regression	497:534	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	39	theme	least	505:509	arg1	PLS					520:522	PLS	520:522	PLS	520:522	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	40	theme	square	1375:1380	arg1	error					1382:1386	root mean square error	1365:1386	root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1365:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	41	theme	values	1410:1415	arg1	error					1382:1386	root mean square error	1365:1386	root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1365:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	5	42	theme	transfer	965:972	arg1	methods					974:980	calibration transfer methods	953:980	calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS)	953:1058	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	3	43	theme	mean	660:663	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	44	theme	RMSEP	1403:1407	arg1	values					1410:1415	prediction (RMSEP) values	1391:1415	prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1391:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	4	45	theme	final	803:807	arg1	product					809:815	the final product	799:815	the final product	799:815	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	3	46	theme	corresponding	641:653	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	47	theme	reference	1223:1231	arg1	method					1233:1238	a reference method	1221:1238	a reference method	1221:1238	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	47	theme	reference	1223:1231	arg1	chromatography					1196:1209	high-performance liquid chromatography	1172:1209	high-performance liquid chromatography (HPLC)	1172:1216	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	2	48	theme	milk	278:281	arg1	tablets					283:289	milk tablets	278:289	milk tablets using near-infrared (NIR) spectroscopy	278:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	6	49	theme	prediction	1391:1400	arg1	values					1410:1415	prediction (RMSEP) values	1391:1415	prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1391:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	4	50	theme	milk	817:820	arg1	samples					829:835	milk tablet samples	817:835	milk tablet samples	817:835	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	3	51	theme	calibration	681:691	arg1	values					701:706	calibration (RMSEC) values	681:706	calibration (RMSEC) values of 1.69 and 0.35	681:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	5	52	from	samples	1122:1128	arg1	spectra					1088:1094	the NIR spectra	1080:1094	the NIR spectra from the real milk tablet samples before the quantitative prediction	1080:1163	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	3	53	theme	partial	497:503	arg1	squares					511:517	partial least squares	497:517	partial least squares (PLS) regression	497:534	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	53	theme	partial	497:503	arg1	PLS					520:522	PLS	520:522	PLS	520:522	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	54	theme	Q2	1463:1464	arg1	values					1466:1471	Q2 values	1463:1471	Q2 values	1463:1471	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	4	55	theme	laboratory-scale	771:786	arg1	powder					788:793	the laboratory-scale powder	767:793	the laboratory-scale powder	767:793	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	6	56	theme	4.22	1453:1456	arg1	lactose					1433:1439	lactose	1433:1439	lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1433:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	56	theme	4.22	1453:1456	arg1	sucrose					1421:1427	sucrose	1421:1427	sucrose	1421:1427	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	57	theme	values	701:706	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	58	theme	5.04	1444:1447	arg1	lactose					1433:1439	lactose	1433:1439	lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1433:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	58	theme	5.04	1444:1447	arg1	sucrose					1421:1427	sucrose	1421:1427	sucrose	1421:1427	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	59	theme	RMSEC	694:698	arg1	values					701:706	calibration (RMSEC) values	681:706	calibration (RMSEC) values of 1.69 and 0.35	681:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	5	60	theme	direct	1031:1036	arg1	PDS					1055:1057	PDS	1055:1057	PDS	1055:1057	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	5	60	theme	direct	1031:1036	arg1	standardization					1038:1052	piecewise direct standardization	1021:1052	piecewise direct standardization (PDS)	1021:1058	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	6	61	theme	real	1334:1337	arg1	tablets					1344:1350	real milk tablets	1334:1350	real milk tablets	1334:1350	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	62	theme	liquid	1189:1194	arg1	method					1233:1238	a reference method	1221:1238	a reference method	1221:1238	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	62	theme	liquid	1189:1194	arg1	HPLC					1212:1215	HPLC	1212:1215	HPLC	1212:1215	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	6	62	theme	liquid	1189:1194	arg1	chromatography					1196:1209	high-performance liquid chromatography	1172:1209	high-performance liquid chromatography (HPLC)	1172:1216	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	4	63	theme	predictive	900:909	arg1	performance					911:921	the predictive performance	896:921	the predictive performance of the PLS models	896:939	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	6	64	used	used	1286:1289	arg2	model					1271:1275	the developed NIR-chemometric model	1241:1275	the developed NIR-chemometric model	1241:1275	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	65	theme	1.69	711:714	arg1	values					701:706	calibration (RMSEC) values	681:706	calibration (RMSEC) values of 1.69 and 0.35	681:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	66	theme	developed	1245:1253	arg1	model					1271:1275	the developed NIR-chemometric model	1241:1275	the developed NIR-chemometric model	1241:1275	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	67	theme	contents	579:586	arg1	predictions					544:554	the predictions	540:554	the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	540:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	1	68	theme	popular	124:130	arg1	product					138:144	a popular dairy product	122:144	a popular dairy product in many Asian countries	122:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	1	68	theme	popular	124:130	arg1	tablets					110:116	Milk tablets	105:116	Milk tablets	105:116	Milk tablets are a popular dairy product in many Asian countries.					
36335160	6	69	theme	milk	1339:1342	arg1	tablets					1344:1350	real milk tablets	1334:1350	real milk tablets	1334:1350	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	0	70	from	sugars	26:31	arg1	tablets					41:47	milk tablets	36:47	milk tablets	36:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	0	71	theme	chemometric	86:96	arg1	tools					98:102	chemometric tools	86:102	chemometric tools	86:102	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	6	72	from	contents	1322:1329	arg1	tablets					1344:1350	real milk tablets	1334:1350	real milk tablets	1334:1350	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	1	73	theme	many	149:152	arg1	countries					160:168	many Asian countries	149:168	many Asian countries	149:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	4	74	theme	models	934:939	arg1	performance					911:921	the predictive performance	896:921	the predictive performance of the PLS models	896:939	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	0	75	from	quantification	8:21	arg1	tablets					41:47	milk tablets	36:47	milk tablets	36:47	Instant quantification of sugars in milk tablets using near-infrared spectroscopy and chemometric tools.					
36335160	6	76	theme	sugar	1316:1320	arg1	contents					1322:1329	the sugar contents	1312:1329	the sugar contents in real milk tablets	1312:1350	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	5	77	theme	NIR	1084:1086	arg1	spectra					1088:1094	the NIR spectra	1080:1094	the NIR spectra from the real milk tablet samples before the quantitative prediction	1080:1163	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	4	78	dep	powder	788:793	arg1	samples					829:835	milk tablet samples	817:835	milk tablet samples	817:835	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	5	79	theme	tablet	1115:1120	arg1	samples					1122:1128	the real milk tablet samples	1101:1128	the real milk tablet samples	1101:1128	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	1	80	theme	Milk	105:108	arg1	product					138:144	a popular dairy product	122:144	a popular dairy product in many Asian countries	122:168	Milk tablets are a popular dairy product in many Asian countries.					
36335160	1	80	theme	Milk	105:108	arg1	tablets					110:116	Milk tablets	105:116	Milk tablets	105:116	Milk tablets are a popular dairy product in many Asian countries.					
36335160	3	81	theme	composite	452:460	arg1	CCD					470:472	CCD	470:472	CCD	470:472	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	81	theme	composite	452:460	arg1	design					462:467	a central composite design	442:467	a central composite design (CCD)	442:473	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	6	82	theme	root	1365:1368	arg1	error					1382:1386	root mean square error	1365:1386	root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively	1365:1506	Using high-performance liquid chromatography (HPLC) as a reference method, the developed NIR-chemometric model could be used to instantly predict the sugar contents in real milk tablets by producing root mean square error of prediction (RMSEP) values for sucrose and lactose of 5.04 and 4.22 with Q2 values of 0.7973 and 0.9411, respectively, after the PDS transformation.					
36335160	3	83	theme	milk	406:409	arg1	samples					411:417	laboratory-scale milk samples	389:417	laboratory-scale milk samples	389:417	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	4	84	theme	physical	739:746	arg1	difference					748:757	the physical difference	735:757	the physical difference between the laboratory-scale powder and the final product milk tablet samples	735:835	However, the physical difference between the laboratory-scale powder and the final product milk tablet samples resulted in spectral deviations that dramatically affected the predictive performance of the PLS models.					
36335160	5	85	theme	direct	989:994	arg1	DS					1013:1014	DS	1013:1014	DS	1013:1014	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	5	85	theme	direct	989:994	arg1	standardization					996:1010	direct standardization	989:1010	direct standardization (DS)	989:1015	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	3	86	theme	0.9987	625:630	arg1	values					604:609	R2 values	601:609	R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	601:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	5	87	theme	real	1105:1108	arg1	samples					1122:1128	the real milk tablet samples	1101:1128	the real milk tablet samples	1101:1128	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	3	88	theme	sucrose	559:565	arg1	predictions					544:554	the predictions	540:554	the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	540:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	2	89	theme	rapid	217:221	arg1	method					223:228	an instant and rapid method	202:228	an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy	202:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	3	90	theme	0.9749	614:619	arg1	values					604:609	R2 values	601:609	R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	601:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	2	91	theme	NIR	312:314	arg1	spectroscopy					317:328	near-infrared (NIR) spectroscopy	297:328	near-infrared (NIR) spectroscopy	297:328	This research aimed to develop an instant and rapid method for determining sucrose and lactose contents in milk tablets using near-infrared (NIR) spectroscopy.					
36335160	5	92	theme	calibration	953:963	arg1	methods					974:980	calibration transfer methods	953:980	calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS)	953:1058	Therefore, calibration transfer methods called direct standardization (DS) and piecewise direct standardization (PDS) were used to adjust the NIR spectra from the real milk tablet samples before the quantitative prediction.					
36335160	3	93	theme	root	655:658	arg1	error					672:676	the corresponding root mean square error	637:676	the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35	637:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36335160	3	94	theme	0.35	720:723	arg1	values					701:706	calibration (RMSEC) values	681:706	calibration (RMSEC) values of 1.69 and 0.35	681:723	For the quantitative analysis, a training set composed of laboratory-scale milk samples was generated based on a central composite design (CCD) and used to establish partial least squares (PLS) regression for the predictions of sucrose and lactose contents resulting in R2 values of 0.9749 and 0.9987 with the corresponding root mean square error of calibration (RMSEC) values of 1.69 and 0.35.					
36122524	3	0	theme	spill	691:695	arg1	problem					697:703	the ocean oil spill problem	677:703	the ocean oil spill problem	677:703	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	1	from	strain	448:453	arg1	340 kPa					432:438	340 kPa	432:438	340 kPa at 90 % strain	432:453	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	2	2	theme	adsorption	362:371	arg1	capacity					373:380	superior selective adsorption capacity	343:380	superior selective adsorption capacity	343:380	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	0	3	theme	bidirectional	92:104	arg1	freeze-drying					106:118	bidirectional freeze-drying	92:118	bidirectional freeze-drying for water-oil separation in the ocean environment	92:168	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	2	4	contain	has	339:341	arg2	capacity					373:380	superior selective adsorption capacity	343:380	superior selective adsorption capacity	343:380	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	2	4	contain	has	339:341	arg1	aerogel					331:337	biomass aerogel	323:337	biomass aerogel	323:337	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	2	5	theme	selective	352:360	arg1	capacity					373:380	superior selective adsorption capacity	343:380	superior selective adsorption capacity	343:380	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	0	6	theme	water-oil	124:132	arg1	separation					134:143	water-oil separation	124:143	water-oil separation in the ocean environment	124:168	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	3	7	theme	ocean	681:685	arg1	problem					697:703	the ocean oil spill problem	677:703	the ocean oil spill problem	677:703	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	6	8	from	applications	1074:1085	arg1	separation					1100:1109	water-oil separation	1090:1109	water-oil separation	1090:1109	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	4	9	theme	green	754:758	arg1	technology					738:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	4	9	theme	green	754:758	arg1	technique					774:782	a green and efficient technique	752:782	a green and efficient technique for preparing layered microstructured composite aerogels	752:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	1	10	theme	oil	270:272	arg1	spills					274:279	oil spills	270:279	oil spills	270:279	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
36122524	4	11	theme	freeze-drying	724:736	arg1	technology					738:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	4	11	theme	freeze-drying	724:736	arg1	technique					774:782	a green and efficient technique	752:782	a green and efficient technique for preparing layered microstructured composite aerogels	752:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	6	12	theme	water-oil	1090:1098	arg1	separation					1100:1109	water-oil separation	1090:1109	water-oil separation	1090:1109	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	3	13	theme	cellulose	521:529	arg1	CNF					543:545	CNF	543:545	CNF	543:545	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	13	theme	cellulose	521:529	arg1	nanofibers					531:540	cellulose nanofibers	521:540	cellulose nanofibers (CNF)	521:546	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	14	theme	%	446:446	arg1	strain					448:453	90 % strain	443:453	90 % strain	443:453	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	15	dep	properties	420:429	arg1	340 kPa					432:438	340 kPa	432:438	340 kPa at 90 % strain	432:453	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	4	16	theme	efficient	764:772	arg1	technology					738:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	4	16	theme	efficient	764:772	arg1	technique					774:782	a green and efficient technique	752:782	a green and efficient technique for preparing layered microstructured composite aerogels	752:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	5	17	theme	interpenetrating	889:904	arg1	structure					915:923	a three-dimensional interpenetrating lamellar structure	869:923	a three-dimensional interpenetrating lamellar structure	869:923	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg1	aerogels					855:862	The prepared aerogels	842:862	The prepared aerogels	842:862	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	density					930:936	low density	926:936	low density (24.2 mg/cm3)	926:950	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	structure					915:923	a three-dimensional interpenetrating lamellar structure	869:923	a three-dimensional interpenetrating lamellar structure	869:923	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	porosity					958:965	high porosity	953:965	high porosity (97.85 %)	953:975	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	%					974:974	97.85 %	968:974	97.85 %	968:974	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	24.2 mg/cm3					939:949	24.2 mg/cm3	939:949	24.2 mg/cm3	939:949	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	hydrophobicity					987:1000	high hydrophobicity	982:1000	high hydrophobicity (WCA = 144.5°)	982:1015	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	18	contain	have	864:867	arg2	WCA = 144.5°					1003:1014	WCA = 144.5°	1003:1014	WCA = 144.5°	1003:1014	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	3	19	theme	sodium	553:558	arg1	SA					570:571	SA	570:571	SA	570:571	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	19	theme	sodium	553:558	arg1	alginate					560:567	sodium alginate	553:567	sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem	553:703	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	5	20	theme	lamellar	906:913	arg1	structure					915:923	a three-dimensional interpenetrating lamellar structure	869:923	a three-dimensional interpenetrating lamellar structure	869:923	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	3	21	theme	good	404:407	arg1	properties					420:429	good mechanical properties	404:429	good mechanical properties (340 kPa at 90 % strain)	404:454	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	6	22	theme	ocean	1186:1190	arg1	environment					1192:1202	the ocean environment	1182:1202	the ocean environment	1182:1202	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	3	23	with	aerogels	390:397	arg1	88.91 g/g					486:494	88.91 g/g	486:494	88.91 g/g	486:494	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	23	with	aerogels	390:397	arg1	properties					420:429	good mechanical properties	404:429	good mechanical properties (340 kPa at 90 % strain)	404:454	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	23	with	aerogels	390:397	arg1	capacity					476:483	high adsorption capacity	460:483	high adsorption capacity (88.91 g/g)	460:495	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	24	theme	90	443:444	arg1	%					446:446	%	446:446	%	446:446	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	25	theme	CNF/SA	383:388	arg1	aerogels					390:397	CNF/SA aerogels	383:397	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g)	383:495	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	4	26	theme	microstructured	806:820	arg1	aerogels					832:839	layered microstructured composite aerogels	798:839	layered microstructured composite aerogels	798:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	0	27	theme	ocean	152:156	arg1	environment					158:168	the ocean environment	148:168	the ocean environment	148:168	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	5	28	theme	high	953:956	arg1	porosity					958:965	high porosity	953:965	high porosity (97.85 %)	953:975	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	28	theme	high	953:956	arg1	%					974:974	97.85 %	968:974	97.85 %	968:974	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	2	29	theme	adsorbent	302:310	arg1	materials					312:320	other adsorbent materials	296:320	other adsorbent materials	296:320	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	3	30	theme	high	460:463	arg1	88.91 g/g					486:494	88.91 g/g	486:494	88.91 g/g	486:494	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	30	theme	high	460:463	arg1	capacity					476:483	high adsorption capacity	460:483	high adsorption capacity (88.91 g/g)	460:495	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	0	31	theme	antifouling	15:25	arg1	nanofibers/alginate					60:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	6	32	theme	oil	1168:1170	arg1	spills					1172:1177	oil spills	1168:1177	oil spills	1168:1177	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	2	33	theme	other	296:300	arg1	materials					312:320	other adsorbent materials	296:320	other adsorbent materials	296:320	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	3	34	theme	adsorption	465:474	arg1	88.91 g/g					486:494	88.91 g/g	486:494	88.91 g/g	486:494	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	34	theme	adsorption	465:474	arg1	capacity					476:483	high adsorption capacity	460:483	high adsorption capacity (88.91 g/g)	460:495	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	0	35	theme	hydrophobic	38:48	arg1	nanofibers/alginate					60:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	3	36	theme	surface	635:641	arg1	modification					643:654	surface modification	635:654	surface modification	635:654	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	5	37	theme	three-dimensional	871:887	arg1	structure					915:923	a three-dimensional interpenetrating lamellar structure	869:923	a three-dimensional interpenetrating lamellar structure	869:923	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	4	38	theme	composite	822:830	arg1	aerogels					832:839	layered microstructured composite aerogels	798:839	layered microstructured composite aerogels	798:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	0	39	theme	nanofibers/alginate	60:78	arg1	Preparation					0:10	Preparation	0:10	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate	0:78	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	6	40	contain	has	1060:1062	arg2	applications					1074:1085	potential applications	1064:1085	potential applications in water-oil separation	1064:1109	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	6	40	contain	has	1060:1062	arg1	absorbent					1133:1141	an absorbent	1130:1141	an absorbent for effectively treating oil spills in the ocean environment	1130:1202	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	6	40	contain	has	1060:1062	arg1	It					1057:1058	It	1057:1058	It	1057:1058	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	2	41	theme	superior	343:350	arg1	capacity					373:380	superior selective adsorption capacity	343:380	superior selective adsorption capacity	343:380	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	0	42	theme	cellulose	50:58	arg1	nanofibers/alginate					60:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	antifouling and highly hydrophobic cellulose nanofibers/alginate	15:78	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	0	43	from	separation	134:143	arg1	environment					158:168	the ocean environment	148:168	the ocean environment	148:168	Preparation of antifouling and highly hydrophobic cellulose nanofibers/alginate aerogels by bidirectional freeze-drying for water-oil separation in the ocean environment.					
36122524	5	44	dep	have	864:867	arg1	used					1040:1043	used	1040:1043	used repeatedly	1040:1054	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	44	dep	have	864:867	arg1	calibrated					1025:1034	calibrated	1025:1034	calibrated	1025:1034	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	1	45	with	deal	260:263	arg1	spills					274:279	oil spills	270:279	oil spills	270:279	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
36122524	4	46	theme	bidirectional	710:722	arg1	technology					738:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology	706:747	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	4	46	theme	bidirectional	710:722	arg1	technique					774:782	a green and efficient technique	752:782	a green and efficient technique for preparing layered microstructured composite aerogels	752:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	5	47	theme	high	982:985	arg1	WCA = 144.5°					1003:1014	WCA = 144.5°	1003:1014	WCA = 144.5°	1003:1014	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	47	theme	high	982:985	arg1	hydrophobicity					987:1000	high hydrophobicity	982:1000	high hydrophobicity (WCA = 144.5°)	982:1015	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	3	48	theme	ionic	611:615	arg1	crosslinking					617:628	ionic crosslinking	611:628	ionic crosslinking	611:628	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	2	49	theme	biomass	323:329	arg1	aerogel					331:337	biomass aerogel	323:337	biomass aerogel	323:337	Compared with other adsorbent materials, biomass aerogel has superior selective adsorption capacity.					
36122524	3	50	theme	bidirectional	582:594	arg1	freeze-drying					596:608	bidirectional freeze-drying	582:608	bidirectional freeze-drying	582:608	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	5	51	theme	prepared	846:853	arg1	aerogels					855:862	The prepared aerogels	842:862	The prepared aerogels	842:862	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	1	52	theme	Oil	171:173	arg1	spills					175:180	Oil spills	171:180	Oil spills	171:180	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
36122524	6	53	theme	potential	1064:1072	arg1	applications					1074:1085	potential applications	1064:1085	potential applications in water-oil separation	1064:1109	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	1	54	theme	effective	242:250	arg1	ways					252:255	the effective ways	238:255	the effective ways	238:255	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
36122524	3	55	theme	mechanical	409:418	arg1	properties					420:429	good mechanical properties	404:429	good mechanical properties (340 kPa at 90 % strain)	404:454	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	3	56	theme	oil	687:689	arg1	problem					697:703	the ocean oil spill problem	677:703	the ocean oil spill problem	677:703	CNF/SA aerogels with good mechanical properties (340 kPa at 90 % strain) and high adsorption capacity (88.91 g/g) were prepared by mixing cellulose nanofibers (CNF) with sodium alginate (SA) through bidirectional freeze-drying, ionic crosslinking, and surface modification to effectively solve the ocean oil spill problem.					
36122524	4	57	theme	layered	798:804	arg1	aerogels					832:839	layered microstructured composite aerogels	798:839	layered microstructured composite aerogels	798:839	The bidirectional freeze-drying technology is a green and efficient technique for preparing layered microstructured composite aerogels.					
36122524	6	58	used	used	1122:1125	arg2	It					1057:1058	It	1057:1058	It	1057:1058	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	6	58	used	used	1122:1125	arg2	absorbent					1133:1141	an absorbent	1130:1141	an absorbent for effectively treating oil spills in the ocean environment	1130:1202	It has potential applications in water-oil separation and can be used as an absorbent for effectively treating oil spills in the ocean environment.					
36122524	5	59	theme	low	926:928	arg1	density					930:936	low density	926:936	low density (24.2 mg/cm3)	926:950	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	5	59	theme	low	926:928	arg1	24.2 mg/cm3					939:949	24.2 mg/cm3	939:949	24.2 mg/cm3	939:949	The prepared aerogels have a three-dimensional interpenetrating lamellar structure, low density (24.2 mg/cm3), high porosity (97.85 %), and high hydrophobicity (WCA = 144.5°), can be calibrated and used repeatedly.					
36122524	1	60	theme	ways	252:255	arg1	ways					252:255	the effective ways	238:255	the effective ways	238:255	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
36122524	1	60	theme	ways	252:255	arg1	one					231:233	one	231:233	one	231:233	Oil spills frequently occur in the ocean, and adsorption is one of the effective ways to deal with oil spills.					
35354277	0	0	theme	Chemical	83:90	arg1	Films					19:23	Photonic Cellulose Films	0:23	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.	0:100	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	0	theme	Chemical	83:90	arg1	Response					92:99	Selectively Chemical Response	71:99	Selectively Chemical Response	71:99	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	1	1	theme	given	344:348	arg1	chemicals					350:358	given chemicals	344:358	given chemicals as well as the corresponding mechanism	344:397	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	5	2	theme	similitude	927:936	arg1	principle					938:946	the compatibility and similitude principle	905:946	principle	938:946	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	6	3	with	sensors	1257:1263	arg1	objects					1291:1297	specifically testing objects	1270:1297	specifically testing objects	1270:1297	The findings pave the foundation for the design of colorimetric sensors with specifically testing objects.					
35354277	5	4	theme	sensing	1136:1142	arg1	selectivity					1144:1154	the sensing selectivity	1132:1154	the sensing selectivity of the chemochromic composite films	1132:1190	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	2	5	theme	vivid	513:517	arg1	films					546:550	vivid structural-color composite films	513:550	vivid structural-color composite films	513:550	Here, a dopamine-infiltration and post-polymerization approach is proposed to construct vivid structural-color composite films.					
35354277	5	6	theme	principle	938:946	arg1	viewpoint					892:900	the viewpoint	888:900	the viewpoint of the compatibility and similitude principle	888:946	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	1	7	theme	sufficient	258:267	arg1	chroma					275:280	sufficient color chroma	258:280	sufficient color chroma for naked-eye observation	258:306	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	3	8	theme	color	717:721	arg1	chroma					723:728	the color chroma	713:728	the color chroma	713:728	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	4	9	theme	composite	781:789	arg1	films					791:795	the composite films	777:795	the composite films	777:795	By controlling the PDA amount, the composite films can detect organic solvents quantitatively and selectively via visible color changes.					
35354277	1	10	theme	color	269:273	arg1	chroma					275:280	sufficient color chroma	258:280	sufficient color chroma for naked-eye observation	258:306	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	4	11	theme	PDA	765:767	arg1	amount					769:774	the PDA amount	761:774	the PDA amount	761:774	By controlling the PDA amount, the composite films can detect organic solvents quantitatively and selectively via visible color changes.					
35354277	3	12	theme	CNC	585:587	arg1	structure					572:580	The chiral nematic structure	553:580	The chiral nematic structure of CNC	553:587	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	6	13	theme	testing	1283:1289	arg1	objects					1291:1297	specifically testing objects	1270:1297	specifically testing objects	1270:1297	The findings pave the foundation for the design of colorimetric sensors with specifically testing objects.					
35354277	3	14	theme	nematic	564:570	arg1	structure					572:580	The chiral nematic structure	553:580	The chiral nematic structure of CNC	553:587	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	4	15	theme	color	868:872	arg1	changes					874:880	visible color changes	860:880	visible color changes	860:880	By controlling the PDA amount, the composite films can detect organic solvents quantitatively and selectively via visible color changes.					
35354277	5	16	theme	critical	960:967	arg1	R0					1000:1001	R0	1000:1001	R0	1000:1001	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	5	16	theme	critical	960:967	arg1	distance					990:997	a critical solubility parameter distance	958:997	a critical solubility parameter distance (R0) between PDA and "active" solvents	958:1036	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	5	17	theme	chemochromic	1163:1174	arg1	films					1186:1190	the chemochromic composite films	1159:1190	the chemochromic composite films	1159:1190	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	0	18	theme	Cellulose	9:17	arg1	Films					19:23	Photonic Cellulose Films	0:23	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.	0:100	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	18	theme	Cellulose	9:17	arg1	Fabrication					55:65	Fabrication	55:65	Fabrication	55:65	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	18	theme	Cellulose	9:17	arg1	Response					92:99	Selectively Chemical Response	71:99	Selectively Chemical Response	71:99	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	1	19	theme	corresponding	375:387	arg1	mechanism					389:397	the corresponding mechanism	371:397	given chemicals as well as the corresponding mechanism	344:397	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	3	20	theme	structural	601:610	arg1	coloration					612:621	the structural coloration	597:621	the structural coloration	597:621	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	0	21	theme	Photonic	0:7	arg1	Films					19:23	Photonic Cellulose Films	0:23	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.	0:100	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	21	theme	Photonic	0:7	arg1	Fabrication					55:65	Fabrication	55:65	Fabrication	55:65	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	21	theme	Photonic	0:7	arg1	Response					92:99	Selectively Chemical Response	71:99	Selectively Chemical Response	71:99	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	5	22	theme	films	1186:1190	arg1	selectivity					1144:1154	the sensing selectivity	1132:1154	the sensing selectivity of the chemochromic composite films	1132:1190	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	6	23	theme	sensors	1257:1263	arg1	design					1234:1239	the design	1230:1239	the design of colorimetric sensors with specifically testing objects	1230:1297	The findings pave the foundation for the design of colorimetric sensors with specifically testing objects.					
35354277	5	24	theme	solubility	969:978	arg1	R0					1000:1001	R0	1000:1001	R0	1000:1001	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	5	24	theme	solubility	969:978	arg1	distance					990:997	a critical solubility parameter distance	958:997	a critical solubility parameter distance (R0) between PDA and "active" solvents	958:1036	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	2	25	theme	dopamine-infiltration	433:453	arg1	approach					479:486	a dopamine-infiltration and post-polymerization approach	431:486	a dopamine-infiltration and post-polymerization approach	431:486	Here, a dopamine-infiltration and post-polymerization approach is proposed to construct vivid structural-color composite films.					
35354277	1	26	theme	naked-eye	286:294	arg1	observation					296:306	naked-eye observation	286:306	naked-eye observation	286:306	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	27	theme	Recent	102:107	arg1	advances					109:116	Recent advances	102:116	Recent advances in structural-color cellulose nanocrystal (CNC) materials	102:174	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	28	theme	chemical	198:205	arg1	applications					215:226	chemical sensing applications	198:226	chemical sensing applications	198:226	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	3	29	theme	chiral	557:562	arg1	structure					572:580	The chiral nematic structure	553:580	The chiral nematic structure of CNC	553:587	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	5	30	theme	solubility	1081:1090	arg1	sphere					1092:1097	a three-dimensional Hansen solubility sphere	1054:1097	a three-dimensional Hansen solubility sphere	1054:1097	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	1	31	theme	sensing	207:213	arg1	applications					215:226	chemical sensing applications	198:226	chemical sensing applications	198:226	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	0	32	theme	Structural	36:45	arg1	Colors					47:52	Vivid Structural Colors	30:52	Vivid Structural Colors	30:52	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	6	33	theme	colorimetric	1244:1255	arg1	sensors					1257:1263	colorimetric sensors	1244:1263	colorimetric sensors with specifically testing objects	1244:1297	The findings pave the foundation for the design of colorimetric sensors with specifically testing objects.					
35354277	5	34	dep	PDA	1012:1014	arg1	solvents					1029:1036	solvents	1029:1036	solvents	1029:1036	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	0	35	theme	Vivid	30:34	arg1	Colors					47:52	Vivid Structural Colors	30:52	Vivid Structural Colors	30:52	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	3	36	theme	polymeric	665:673	arg1	polydopamine					685:696	polydopamine	685:696	polydopamine (PDA)	685:702	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	3	36	theme	polymeric	665:673	arg1	co-phase					675:682	the polymeric co-phase	661:682	the polymeric co-phase	661:682	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	3	37	theme	strong	634:639	arg1	absorption					647:656	the strong light absorption	630:656	the strong light absorption of the polymeric co-phase, polydopamine (PDA)	630:702	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	3	38	theme	co-phase	675:682	arg1	absorption					647:656	the strong light absorption	630:656	the strong light absorption of the polymeric co-phase, polydopamine (PDA)	630:702	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	4	39	theme	visible	860:866	arg1	changes					874:880	visible color changes	860:880	visible color changes	860:880	By controlling the PDA amount, the composite films can detect organic solvents quantitatively and selectively via visible color changes.					
35354277	0	40	with	Films	19:23	arg1	Colors					47:52	Vivid Structural Colors	30:52	Vivid Structural Colors	30:52	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	5	41	theme	parameter	980:988	arg1	R0					1000:1001	R0	1000:1001	R0	1000:1001	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	5	41	theme	parameter	980:988	arg1	distance					990:997	a critical solubility parameter distance	958:997	a critical solubility parameter distance (R0) between PDA and "active" solvents	958:1036	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	1	42	theme	selective	319:327	arg1	recognition					329:339	their selective recognition	313:339	their selective recognition to given chemicals as well as the corresponding mechanism	313:397	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	43	theme	structural-color	121:136	arg1	CNC					161:163	CNC	161:163	CNC	161:163	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	43	theme	structural-color	121:136	arg1	nanocrystal					148:158	structural-color cellulose nanocrystal	121:158	structural-color cellulose nanocrystal (CNC) materials	121:174	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	5	44	theme	composite	1176:1184	arg1	films					1186:1190	the chemochromic composite films	1159:1190	the chemochromic composite films	1159:1190	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	4	45	theme	organic	808:814	arg1	solvents					816:823	organic solvents	808:823	organic solvents	808:823	By controlling the PDA amount, the composite films can detect organic solvents quantitatively and selectively via visible color changes.					
35354277	1	46	theme	cellulose	138:146	arg1	CNC					161:163	CNC	161:163	CNC	161:163	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	46	theme	cellulose	138:146	arg1	nanocrystal					148:158	structural-color cellulose nanocrystal	121:158	structural-color cellulose nanocrystal (CNC) materials	121:174	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	1	47	from	advances	109:116	arg1	materials					166:174	structural-color cellulose nanocrystal (CNC) materials	121:174	structural-color cellulose nanocrystal (CNC) materials	121:174	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	5	48	theme	three-dimensional	1056:1072	arg1	sphere					1092:1097	a three-dimensional Hansen solubility sphere	1054:1097	a three-dimensional Hansen solubility sphere	1054:1097	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	0	49	dep	Films	19:23	arg1	Films					19:23	Photonic Cellulose Films	0:23	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.	0:100	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	49	dep	Films	19:23	arg1	Fabrication					55:65	Fabrication	55:65	Fabrication	55:65	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	0	49	dep	Films	19:23	arg1	Response					92:99	Selectively Chemical Response	71:99	Selectively Chemical Response	71:99	Photonic Cellulose Films with Vivid Structural Colors: Fabrication and Selectively Chemical Response.					
35354277	1	50	theme	nanocrystal	148:158	arg1	materials					166:174	structural-color cellulose nanocrystal (CNC) materials	121:174	structural-color cellulose nanocrystal (CNC) materials	121:174	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	2	51	theme	composite	536:544	arg1	films					546:550	vivid structural-color composite films	513:550	vivid structural-color composite films	513:550	Here, a dopamine-infiltration and post-polymerization approach is proposed to construct vivid structural-color composite films.					
35354277	5	52	theme	Hansen	1074:1079	arg1	sphere					1092:1097	a three-dimensional Hansen solubility sphere	1054:1097	a three-dimensional Hansen solubility sphere	1054:1097	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	3	53	theme	light	641:645	arg1	absorption					647:656	the strong light absorption	630:656	the strong light absorption of the polymeric co-phase, polydopamine (PDA)	630:702	The chiral nematic structure of CNC enables the structural coloration, while the strong light absorption of the polymeric co-phase, polydopamine (PDA) enhances the color chroma and visibility.					
35354277	5	54	theme	compatibility	909:921	arg1	principle					938:946	the compatibility and similitude principle	905:946	principle	938:946	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	1	55	theme	such	238:241	arg1	materials					243:251	such materials	238:251	such materials	238:251	Recent advances in structural-color cellulose nanocrystal (CNC) materials have been made toward chemical sensing applications; however, such materials lack sufficient color chroma for naked-eye observation, and their selective recognition to given chemicals as well as the corresponding mechanism has rarely been reported.					
35354277	2	56	theme	structural-color	519:534	arg1	films					546:550	vivid structural-color composite films	513:550	vivid structural-color composite films	513:550	Here, a dopamine-infiltration and post-polymerization approach is proposed to construct vivid structural-color composite films.					
35354277	5	57	theme	active	1021:1026	arg1	"					1027:1027	"active"	1020:1027	"active"	1020:1027	From the viewpoint of the compatibility and similitude principle, notably, a critical solubility parameter distance (R0) between PDA and "active" solvents is defined with a three-dimensional Hansen solubility sphere; this well constructs a rule for the sensing selectivity of the chemochromic composite films.					
35354277	2	58	theme	post-polymerization	459:477	arg1	approach					479:486	a dopamine-infiltration and post-polymerization approach	431:486	a dopamine-infiltration and post-polymerization approach	431:486	Here, a dopamine-infiltration and post-polymerization approach is proposed to construct vivid structural-color composite films.					
36356361	12	0	from	fibre	1785:1789	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	0	from	fibre	1785:1789	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	0	from	fibre	1785:1789	arg1	Se					1802:1803	Se	1802:1803	Se	1802:1803	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	0	from	fibre	1785:1789	arg1	protein					1810:1816	protein	1810:1816	protein	1810:1816	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	10	1	theme	variables	1560:1568	arg1	set					1548:1550	a large set	1540:1550	a large set of data variables	1540:1568	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	1	theme	variables	1560:1568	arg1	variables					1560:1568	data variables	1555:1568	data variables	1555:1568	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	8	2	from	clusters	1333:1340	arg1	each					1345:1348	each	1345:1348	each	1345:1348	Based on HCA, dendrogram-1 (nutrients) and dendrogram-2 (minerals, anti-nutrients) were produced, having four clusters in each.					
36356361	5	3	theme	Resistant	630:638	arg1	%					661:661	4.13 to 8.62 %	648:661	4.13 to 8.62 %	648:661	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	5	3	theme	Resistant	630:638	arg1	starch					640:645	Resistant starch	630:645	Resistant starch (4.13 to 8.62 %)	630:662	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	12	4	theme	factor	1675:1680	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	4	theme	factor	1675:1680	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	1	5	theme	Ricebean	157:164	arg1	n = 38					178:183	n = 38	178:183	n = 38	178:183	Ricebean accessions (n = 38) cultivated in India were evaluated for their comprehensive nutrient, anti-nutrients and mineral composition.					
36356361	1	5	theme	Ricebean	157:164	arg1	accessions					166:175	Ricebean accessions	157:175	Ricebean accessions (n = 38) cultivated in India	157:204	Ricebean accessions (n = 38) cultivated in India were evaluated for their comprehensive nutrient, anti-nutrients and mineral composition.					
36356361	10	6	theme	large	1542:1546	arg1	set					1548:1550	a large set	1540:1550	a large set of data variables	1540:1568	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	6	theme	large	1542:1546	arg1	variables					1560:1568	data variables	1555:1568	data variables	1555:1568	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	4	7	theme	free	566:569	arg1	sugars					571:576	the free sugars	562:576	the free sugars	562:576	Among the free sugars, sucrose was found dominating (up to 370 mg/100 g).					
36356361	5	8	dep	8.62 	656:660	arg1	to					653:654	to	653:654	to	653:654	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	0	9	from	Assessment	0:9	arg1	minerals					68:75	minerals	68:75	minerals	68:75	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	9	from	Assessment	0:9	arg1	profile					41:47	anti-nutrient profile	27:47	anti-nutrient profile	27:47	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	9	from	Assessment	0:9	arg1	starch					60:65	resistant starch	50:65	resistant starch	50:65	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	9	from	Assessment	0:9	arg1	components					94:103	carbohydrate components	81:103	carbohydrate components	81:103	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	7	10	theme	Multivariate	1013:1024	arg1	analysis					1026:1033	Multivariate analysis	1013:1033	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA)	1013:1118	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	0	11	theme	carbohydrate	81:92	arg1	components					94:103	carbohydrate components	81:103	carbohydrate components	81:103	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	6	12	theme	Phytic	817:822	arg1	acid					824:827	Phytic acid	817:827	Phytic acid	817:827	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	10	13	theme	uncorrelated	1470:1481	arg1	variables					1490:1498	variables	1490:1498	variables (principal components)	1490:1521	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	13	theme	uncorrelated	1470:1481	arg1	components					1511:1520	principal components	1501:1520	principal components	1501:1520	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	13	theme	uncorrelated	1470:1481	arg1	set					1483:1485	the uncorrelated set	1466:1485	the uncorrelated set of variables (principal components)	1466:1521	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	6	14	dep	46 mg/g	944:950	arg1	to					941:942	to	941:942	to	941:942	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	11	15	theme	%	1668:1668	arg1	variance					1651:1658	total variance	1645:1658	total variance of 78.8 %	1645:1668	Based on the eigenvalue >1, a total of eight PCs were formed contributing total variance of 78.8 %.					
36356361	0	16	theme	different	108:116	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	17	from	profile	41:47	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	12	18	from	iron	1732:1735	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	18	from	iron	1732:1735	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	18	from	iron	1732:1735	arg1	Se					1802:1803	Se	1802:1803	Se	1802:1803	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	18	from	iron	1732:1735	arg1	protein					1810:1816	protein	1810:1816	protein	1810:1816	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	7	19	theme	component	1095:1103	arg1	PCA					1115:1117	PCA	1115:1117	PCA	1115:1117	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	7	19	theme	component	1095:1103	arg1	analysis					1105:1112	principal component analysis	1085:1112	principal component analysis (PCA)	1085:1118	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	5	20	dep	significantly	768:780	arg1	p < 0.05					783:790	p < 0.05	783:790	p < 0.05	783:790	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	8	21	dep	dendrogram-2	1266:1277	arg1	anti-nutrients					1290:1303	anti-nutrients	1290:1303	anti-nutrients	1290:1303	Based on HCA, dendrogram-1 (nutrients) and dendrogram-2 (minerals, anti-nutrients) were produced, having four clusters in each.					
36356361	8	21	dep	dendrogram-2	1266:1277	arg1	minerals					1280:1287	minerals	1280:1287	minerals	1280:1287	Based on HCA, dendrogram-1 (nutrients) and dendrogram-2 (minerals, anti-nutrients) were produced, having four clusters in each.					
36356361	7	22	theme	principal	1085:1093	arg1	PCA					1115:1117	PCA	1115:1117	PCA	1115:1117	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	7	22	theme	principal	1085:1093	arg1	analysis					1105:1112	principal component analysis	1085:1112	principal component analysis (PCA)	1085:1118	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	1	23	theme	mineral	274:280	arg1	composition					282:292	mineral composition	274:292	mineral composition	274:292	Ricebean accessions (n = 38) cultivated in India were evaluated for their comprehensive nutrient, anti-nutrients and mineral composition.					
36356361	5	24	dep	3.72 mg/100 g	709:721	arg1	to					706:707	to	706:707	to	706:707	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	6	25	dep	1076 mg/100 g	960:972	arg1	to					957:958	to	957:958	to	957:958	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	7	26	theme	hierarchical	1041:1052	arg1	HCA					1075:1077	HCA	1075:1077	HCA	1075:1077	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	7	26	theme	hierarchical	1041:1052	arg1	analysis					1065:1072	hierarchical clustering analysis	1041:1072	hierarchical clustering analysis (HCA)	1041:1078	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	12	27	dep	PC1	1710:1712	arg1	the					1706:1708	the	1706:1708	the	1706:1708	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	6	28	theme	ricebean	881:888	arg1	accessions					890:899	ricebean accessions	881:899	ricebean accessions	881:899	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	12	29	theme	loading	1682:1688	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	29	theme	loading	1682:1688	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	0	30	theme	diversity	14:22	arg1	Assessment					0:9	Assessment	0:9	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.	0:155	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	31	theme	ricebean	118:125	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	10	32	theme	data	1555:1558	arg1	variables					1560:1568	data variables	1555:1568	data variables	1555:1568	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	12	33	from	contribution	1690:1701	arg1	PC2					1718:1720	PC2	1718:1720	PC2	1718:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	33	from	contribution	1690:1701	arg1	PC1					1710:1712	PC1	1710:1712	PC1	1710:1712	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	11	34	theme	PCs	1616:1618	arg1	total					1601:1605	a total	1599:1605	a total of eight PCs	1599:1618	Based on the eigenvalue >1, a total of eight PCs were formed contributing total variance of 78.8 %.					
36356361	0	35	theme	umbellata	134:142	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	36	from	minerals	68:75	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	10	37	theme	variables	1490:1498	arg1	variables					1490:1498	variables	1490:1498	variables (principal components)	1490:1521	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	37	theme	variables	1490:1498	arg1	components					1511:1520	principal components	1501:1520	principal components	1501:1520	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	37	theme	variables	1490:1498	arg1	set					1483:1485	the uncorrelated set	1466:1485	the uncorrelated set of variables (principal components)	1466:1521	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	0	38	theme	anti-nutrient	27:39	arg1	profile					41:47	anti-nutrient profile	27:47	anti-nutrient profile	27:47	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	0	39	theme	Vigna	128:132	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	4	40	dep	370 mg/100 g	615:626	arg1	to					612:613	to	612:613	to	612:613	Among the free sugars, sucrose was found dominating (up to 370 mg/100 g).					
36356361	7	41	theme	ricebean	1202:1209	arg1	accessions					1211:1220	the ricebean accessions	1198:1220	the ricebean accessions	1198:1220	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	0	42	theme	resistant	50:58	arg1	starch					60:65	resistant starch	50:65	resistant starch	50:65	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	5	43	dep	7.46 mg/100 g	679:691	arg1	to					676:677	to	676:677	to	676:677	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	0	44	from	starch	60:65	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	7	45	theme	anti-nutrients	1176:1189	arg1	diversity					1149:1157	the diversity	1145:1157	the diversity of nutrients and anti-nutrients across the ricebean accessions	1145:1220	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	12	46	from	raffinose	1757:1765	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	46	from	raffinose	1757:1765	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	46	from	raffinose	1757:1765	arg1	Se					1802:1803	Se	1802:1803	Se	1802:1803	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	46	from	raffinose	1757:1765	arg1	protein					1810:1816	protein	1810:1816	protein	1810:1816	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	47	from	glucose	1748:1754	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	47	from	glucose	1748:1754	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	47	from	glucose	1748:1754	arg1	Se					1802:1803	Se	1802:1803	Se	1802:1803	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	47	from	glucose	1748:1754	arg1	protein					1810:1816	protein	1810:1816	protein	1810:1816	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	6	48	theme	trypsin	839:845	arg1	inhibitor					847:855	trypsin inhibitor	839:855	trypsin inhibitor	839:855	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	9	49	contain	had	1398:1400	arg2	n = 21					1403:1408	(n = 21)	1402:1409	(n = 21)	1402:1409	In the dendrogram-1 and 2, the largest cluster had (n = 21) and (n = 15) accessions, respectively.					
36356361	9	49	contain	had	1398:1400	arg2	accessions					1424:1433	(n = 15) accessions	1415:1433	(n = 15) accessions	1415:1433	In the dendrogram-1 and 2, the largest cluster had (n = 21) and (n = 15) accessions, respectively.					
36356361	9	49	contain	had	1398:1400	arg1	cluster					1390:1396	the largest cluster	1378:1396	the largest cluster	1378:1396	In the dendrogram-1 and 2, the largest cluster had (n = 21) and (n = 15) accessions, respectively.					
36356361	4	50	dep	dominating	597:606	arg1	370 mg/100 g					615:626	370 mg/100 g	615:626	370 mg/100 g	615:626	Among the free sugars, sucrose was found dominating (up to 370 mg/100 g).					
36356361	9	51	dep	dendrogram-1	1358:1369	arg1	the					1354:1356	the	1354:1356	the	1354:1356	In the dendrogram-1 and 2, the largest cluster had (n = 21) and (n = 15) accessions, respectively.					
36356361	6	52	dep	431 mg/100 g	985:996	arg1	to					982:983	to	982:983	to	982:983	Phytic acid, saponin, trypsin inhibitor and oxalate analysed in ricebean accessions ranged between 303 and 760 mg/100 g, 19 to 46 mg/g, 309 to 1076 mg/100 g and 219 to 431 mg/100 g, respectively.					
36356361	3	53	dep	5765 mg/100 g	527:539	arg1	to					524:525	to	524:525	to	524:525	Among the oligosaccharides, verbascose was not detected, however, raffinose and stachyose ranged between 47 and 186 and 117 to 5765 mg/100 g, respectively.					
36356361	0	54	from	components	94:103	arg1	accessions					145:154	different ricebean (Vigna umbellata) accessions	108:154	different ricebean (Vigna umbellata) accessions	108:154	Assessment of diversity in anti-nutrient profile, resistant starch, minerals and carbohydrate components in different ricebean (Vigna umbellata) accessions.					
36356361	2	55	dep	16.69 g/100 g	371:383	arg1	to					368:369	to	368:369	to	368:369	Protein and total dietary fibre ranged between 23.23 and 27.33 and 12.27 to 16.69 g/100 g, respectively.					
36356361	9	56	theme	largest	1382:1388	arg1	cluster					1390:1396	the largest cluster	1378:1396	the largest cluster	1378:1396	In the dendrogram-1 and 2, the largest cluster had (n = 21) and (n = 15) accessions, respectively.					
36356361	7	57	theme	nutrients	1162:1170	arg1	diversity					1149:1157	the diversity	1145:1157	the diversity of nutrients and anti-nutrients across the ricebean accessions	1145:1220	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	12	58	from	fructose	1738:1745	arg1	selenium					1792:1799	selenium	1792:1799	selenium (Se)	1792:1804	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	58	from	fructose	1738:1745	arg1	contribution					1690:1701	The factor loading contribution	1671:1701	The factor loading contribution in the PC1 and PC2	1671:1720	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	58	from	fructose	1738:1745	arg1	Se					1802:1803	Se	1802:1803	Se	1802:1803	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	12	58	from	fructose	1738:1745	arg1	protein					1810:1816	protein	1810:1816	protein	1810:1816	The factor loading contribution in the PC1 and PC2 were from iron, fructose, glucose, raffinose and total dietary fibre, selenium (Se) and protein, respectively.					
36356361	5	59	dep	4.48 µg/100 g	746:758	arg1	to					743:744	to	743:744	to	743:744	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	5	60	theme	ricebean	799:806	arg1	samples					808:814	ricebean samples	799:814	ricebean samples	799:814	Resistant starch (4.13 to 8.62 %), iron (3.49 to 7.46 mg/100 g), zinc (1.90 to 3.72 mg/100 g) and selenium (0.28 to 4.48 µg/100 g) varied significantly (p < 0.05) among ricebean samples.					
36356361	10	61	theme	principal	1501:1509	arg1	variables					1490:1498	variables	1490:1498	variables (principal components)	1490:1521	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	10	61	theme	principal	1501:1509	arg1	components					1511:1520	principal components	1501:1520	principal components	1501:1520	The PCA analyse the uncorrelated set of variables (principal components) and it condenses a large set of data variables.					
36356361	11	62	theme	total	1645:1649	arg1	variance					1651:1658	total variance	1645:1658	total variance of 78.8 %	1645:1668	Based on the eigenvalue >1, a total of eight PCs were formed contributing total variance of 78.8 %.					
36356361	7	63	theme	clustering	1054:1063	arg1	HCA					1075:1077	HCA	1075:1077	HCA	1075:1077	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	7	63	theme	clustering	1054:1063	arg1	analysis					1065:1072	hierarchical clustering analysis	1041:1072	hierarchical clustering analysis (HCA)	1041:1078	Multivariate analysis using hierarchical clustering analysis (HCA), and principal component analysis (PCA) was employed to decipher the diversity of nutrients and anti-nutrients across the ricebean accessions.					
36356361	1	64	theme	comprehensive	231:243	arg1	nutrient					245:252	their comprehensive nutrient	225:252	their comprehensive nutrient	225:252	Ricebean accessions (n = 38) cultivated in India were evaluated for their comprehensive nutrient, anti-nutrients and mineral composition.					
36558171	8	0	theme	sciatic	1117:1123	arg1	nerve					1125:1129	rat sciatic nerve	1113:1129	rat sciatic nerve	1113:1129	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	7	1	theme	internal	964:971	arg1	filler					973:978	the internal filler	960:978	the internal filler of the NGC	960:989	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	7	1	theme	internal	964:971	arg1	effect					1058:1063	a longitudinal guidance effect	1034:1063	a longitudinal guidance effect for nerve reconstruction	1034:1088	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	4	2	theme	inner	666:670	arg1	wall					672:675	The inner wall	662:675	The inner wall of the scaffold	662:691	The inner wall of the scaffold was coated with C-CM-CTS solution.					
36558171	0	3	theme	Conduit	86:92	arg1	Effect					19:24	Nerve Regeneration Effect	0:24	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.	0:115	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	6	4	with	biocompatibility	867:882	arg1	fibroblast					889:898	fibroblast	889:898	fibroblast	889:898	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	6	4	with	biocompatibility	867:882	arg1	inhibition					908:917	its inhibition	904:917	its inhibition of oxidative damage to Schwann cells	904:954	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	9	5	dep	advantages	1385:1394	arg1	addition					1358:1365	addition	1358:1365	addition	1358:1365	In addition to the functional advantages, which are equal to those of an autograft; the technology for the preparation of this conduit can be put into mass production.					
36558171	2	6	theme	regeneration	313:324	arg1	restricted					354:363	restricted	354:363	restricted	354:363	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	2	6	theme	regeneration	313:324	arg1	effect					326:331	the nerve regeneration effect	303:331	the nerve regeneration effect of chitosan	303:343	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	1	7	theme	due	227:229	arg1	defects					219:225	peripheral nerve defects	202:225	peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	202:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	0	8	theme	Radial	101:106	arg1	Texture					108:114	a Radial Texture	99:114	a Radial Texture	99:114	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	5	9	from	bioactivities	754:766	arg1	conduit					806:812	the composite chitosan-based nerve conduit	771:812	the composite chitosan-based nerve conduit	771:812	CM-CTS provided favorable bioactivities in the composite chitosan-based nerve conduit.					
36558171	8	10	theme	10	1097:1098	arg1	mm					1100:1101	mm	1100:1101	mm	1100:1101	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	9	11	theme	mass	1506:1509	arg1	production					1511:1520	mass production	1506:1520	mass production	1506:1520	In addition to the functional advantages, which are equal to those of an autograft; the technology for the preparation of this conduit can be put into mass production.					
36558171	8	12	theme	nerve	1311:1315	arg1	regeneration					1317:1328	nerve regeneration	1311:1328	nerve regeneration	1311:1328	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	1	13	used	used	141:144	arg2	material					180:187	a nerve guidance conduit (NGC) material	149:187	a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	149:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	13	used	used	141:144	arg2	Chitosan					117:124	Chitosan	117:124	Chitosan (CTS)	117:130	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	13	used	used	141:144	arg2	CTS					127:129	CTS	127:129	CTS	127:129	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	8	14	theme	composite	1152:1160	arg1	conduit					1193:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	9	15	theme	functional	1374:1383	arg1	advantages					1385:1394	the functional advantages	1370:1394	the functional advantages	1370:1394	In addition to the functional advantages, which are equal to those of an autograft; the technology for the preparation of this conduit can be put into mass production.					
36558171	9	15	theme	functional	1374:1383	arg1	equal					1407:1411	equal	1407:1411	equal	1407:1411	In addition to the functional advantages, which are equal to those of an autograft; the technology for the preparation of this conduit can be put into mass production.					
36558171	3	16	theme	nerve	454:458	arg1	conduit					460:466	a composite, bioactive chitosan based nerve conduit	416:466	a composite, bioactive chitosan based nerve conduit	416:466	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	7	17	theme	nerve	1069:1073	arg1	reconstruction					1075:1088	nerve reconstruction	1069:1088	nerve reconstruction	1069:1088	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	2	18	theme	inadequate	376:385	arg1	activity					398:405	its inadequate biological activity	372:405	its inadequate biological activity	372:405	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	3	19	theme	warp-knitted	489:500	arg1	scaffold					507:514	outer warp-knitted tube scaffold	483:514	outer warp-knitted tube scaffold made from medical-grade chitosan fiber	483:553	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	6	20	theme	satisfying	856:865	arg1	biocompatibility					867:882	its satisfying biocompatibility	852:882	its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells	852:954	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	5	21	theme	favorable	744:752	arg1	bioactivities					754:766	favorable bioactivities	744:766	favorable bioactivities in the composite chitosan-based nerve conduit	744:812	CM-CTS provided favorable bioactivities in the composite chitosan-based nerve conduit.					
36558171	3	22	link	linked	579:584	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	22	link	linked	579:584	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	1	23	theme	nerve	151:155	arg1	Chitosan					117:124	Chitosan	117:124	Chitosan (CTS)	117:130	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	23	theme	nerve	151:155	arg1	material					180:187	a nerve guidance conduit (NGC) material	149:187	a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	149:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	0	24	theme	Regeneration	6:17	arg1	Effect					19:24	Nerve Regeneration Effect	0:24	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.	0:115	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	6	25	dep	in	818:819	arg1	vitro					821:825	vitro	821:825	vitro	821:825	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	3	26	theme	chitosan	540:547	arg1	fiber					549:553	medical-grade chitosan fiber	526:553	medical-grade chitosan fiber	526:553	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	1	27	theme	guidance	157:164	arg1	Chitosan					117:124	Chitosan	117:124	Chitosan (CTS)	117:130	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	27	theme	guidance	157:164	arg1	material					180:187	a nerve guidance conduit (NGC) material	149:187	a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	149:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	0	28	theme	Nerve	0:4	arg1	Effect					19:24	Nerve Regeneration Effect	0:24	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.	0:115	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	1	29	theme	biocompatible	238:250	arg1	properties					282:291	its biocompatible, biodegradable, and non-toxic properties	234:291	its biocompatible, biodegradable, and non-toxic properties	234:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	8	30	theme	functional	1334:1343	arg1	recovery					1345:1352	functional recovery	1334:1352	functional recovery	1334:1352	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	1	31	theme	conduit	166:172	arg1	Chitosan					117:124	Chitosan	117:124	Chitosan (CTS)	117:130	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	31	theme	conduit	166:172	arg1	material					180:187	a nerve guidance conduit (NGC) material	149:187	a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	149:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	5	32	theme	nerve	800:804	arg1	conduit					806:812	the composite chitosan-based nerve conduit	771:812	the composite chitosan-based nerve conduit	771:812	CM-CTS provided favorable bioactivities in the composite chitosan-based nerve conduit.					
36558171	5	33	theme	chitosan-based	785:798	arg1	conduit					806:812	the composite chitosan-based nerve conduit	771:812	the composite chitosan-based nerve conduit	771:812	CM-CTS provided favorable bioactivities in the composite chitosan-based nerve conduit.					
36558171	7	34	theme	longitudinal	1036:1047	arg1	filler					973:978	the internal filler	960:978	the internal filler of the NGC	960:989	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	7	34	theme	longitudinal	1036:1047	arg1	effect					1058:1063	a longitudinal guidance effect	1034:1063	a longitudinal guidance effect for nerve reconstruction	1034:1088	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	8	35	theme	chitosan-based	1172:1185	arg1	conduit					1193:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	4	36	theme	C-CM-CTS	709:716	arg1	solution					718:725	C-CM-CTS solution	709:725	C-CM-CTS solution	709:725	The inner wall of the scaffold was coated with C-CM-CTS solution.					
36558171	8	37	theme	positive	1285:1292	arg1	role					1294:1297	a positive role	1283:1297	a positive role	1283:1297	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	2	38	theme	biological	387:396	arg1	activity					398:405	its inadequate biological activity	372:405	its inadequate biological activity	372:405	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	8	39	theme	bioactive	1162:1170	arg1	conduit					1193:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	1	40	theme	biodegradable	253:265	arg1	properties					282:291	its biocompatible, biodegradable, and non-toxic properties	234:291	its biocompatible, biodegradable, and non-toxic properties	234:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	7	41	theme	guidance	1049:1056	arg1	filler					973:978	the internal filler	960:978	the internal filler of the NGC	960:989	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	7	41	theme	guidance	1049:1056	arg1	effect					1058:1063	a longitudinal guidance effect	1034:1063	a longitudinal guidance effect for nerve reconstruction	1034:1088	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	3	42	theme	medical-grade	526:538	arg1	fiber					549:553	medical-grade chitosan fiber	526:553	medical-grade chitosan fiber	526:553	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	1	43	theme	NGC	175:177	arg1	Chitosan					117:124	Chitosan	117:124	Chitosan (CTS)	117:130	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	1	43	theme	NGC	175:177	arg1	material					180:187	a nerve guidance conduit (NGC) material	149:187	a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	149:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	0	44	theme	Composite	31:39	arg1	Conduit					86:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	6	45	theme	Schwann	942:948	arg1	cells					950:954	Schwann cells	942:954	Schwann cells	942:954	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	6	46	theme	CM-CTS	836:841	arg1	study					827:831	An in vitro study	815:831	An in vitro study of CM-CTS	815:841	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	3	47	theme	inner	560:564	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	47	theme	inner	560:564	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	8	48	theme	axonal	1252:1257	arg1	regeneration					1259:1270	axonal regeneration	1252:1270	axonal regeneration	1252:1270	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	8	49	theme	nerve	1187:1191	arg1	conduit					1193:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	the composite bioactive chitosan-based nerve conduit	1148:1199	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	8	50	theme	rat	1113:1115	arg1	nerve					1125:1129	rat sciatic nerve	1113:1129	rat sciatic nerve	1113:1129	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	3	51	theme	porous	566:571	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	51	theme	porous	566:571	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	52	theme	composite	418:426	arg1	conduit					460:466	a composite, bioactive chitosan based nerve conduit	416:466	a composite, bioactive chitosan based nerve conduit	416:466	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	0	53	theme	Carboxymethyl	51:63	arg1	Conduit					86:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	1	54	theme	non-toxic	272:280	arg1	properties					282:291	its biocompatible, biodegradable, and non-toxic properties	234:291	its biocompatible, biodegradable, and non-toxic properties	234:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	9	55	theme	conduit	1482:1488	arg1	preparation					1462:1472	the preparation	1458:1472	the preparation of this conduit	1458:1488	In addition to the functional advantages, which are equal to those of an autograft; the technology for the preparation of this conduit can be put into mass production.					
36558171	8	56	from	defect	1103:1108	arg1	nerve					1125:1129	rat sciatic nerve	1113:1129	rat sciatic nerve	1113:1129	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	0	57	with	Effect	19:24	arg1	Texture					108:114	a Radial Texture	99:114	a Radial Texture	99:114	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	2	58	theme	nerve	307:311	arg1	regeneration					313:324	nerve regeneration	307:324	the nerve regeneration effect of chitosan	303:343	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	0	59	theme	Bioactive	41:49	arg1	Conduit					86:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	6	60	theme	oxidative	922:930	arg1	damage					932:937	oxidative damage	922:937	oxidative damage to Schwann cells	922:954	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	7	61	theme	C-CM-CTS	1018:1025	arg1	sponge					1008:1013	the lyophilized sponge	992:1013	the lyophilized sponge of C-CM-CTS	992:1025	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	7	62	theme	lyophilized	996:1006	arg1	sponge					1008:1013	the lyophilized sponge	992:1013	the lyophilized sponge of C-CM-CTS	992:1025	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	6	63	theme	in	818:819	arg1	study					827:831	An in vitro study	815:831	An in vitro study of CM-CTS	815:841	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	3	64	theme	carboxymethyl	586:598	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	64	theme	carboxymethyl	586:598	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	7	65	theme	NGC	987:989	arg1	filler					973:978	the internal filler	960:978	the internal filler of the NGC	960:989	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	7	65	theme	NGC	987:989	arg1	effect					1058:1063	a longitudinal guidance effect	1034:1063	a longitudinal guidance effect for nerve reconstruction	1034:1088	As the internal filler of the NGC, the lyophilized sponge of C-CM-CTS showed a longitudinal guidance effect for nerve reconstruction.					
36558171	3	66	theme	chitosan	439:446	arg1	conduit					460:466	a composite, bioactive chitosan based nerve conduit	416:466	a composite, bioactive chitosan based nerve conduit	416:466	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	5	67	theme	composite	775:783	arg1	conduit					806:812	the composite chitosan-based nerve conduit	771:812	the composite chitosan-based nerve conduit	771:812	CM-CTS provided favorable bioactivities in the composite chitosan-based nerve conduit.					
36558171	3	68	theme	tube	502:505	arg1	scaffold					507:514	outer warp-knitted tube scaffold	483:514	outer warp-knitted tube scaffold made from medical-grade chitosan fiber	483:553	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	69	dep	composite	418:426	arg1	bioactive					429:437	bioactive	429:437	bioactive	429:437	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	8	70	theme	mm	1100:1101	arg1	defect					1103:1108	10 mm defect	1097:1108	10 mm defect in rat sciatic nerve	1097:1129	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	3	71	theme	based	448:452	arg1	conduit					460:466	a composite, bioactive chitosan based nerve conduit	416:466	a composite, bioactive chitosan based nerve conduit	416:466	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	4	72	theme	scaffold	684:691	arg1	wall					672:675	The inner wall	662:675	The inner wall of the scaffold	662:691	The inner wall of the scaffold was coated with C-CM-CTS solution.					
36558171	0	73	theme	Nerve	80:84	arg1	Conduit					86:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	3	74	theme	radial	632:637	arg1	texture					639:645	radial texture	632:645	radial texture	632:645	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	75	theme	cross	573:577	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	75	theme	cross	573:577	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	2	76	theme	chitosan	336:343	arg1	restricted					354:363	restricted	354:363	restricted	354:363	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	2	76	theme	chitosan	336:343	arg1	effect					326:331	the nerve regeneration effect	303:331	the nerve regeneration effect of chitosan	303:343	However, the nerve regeneration effect of chitosan alone is restricted due to its inadequate biological activity.					
36558171	8	77	theme	nerve	1206:1210	arg1	able					1224:1227	able	1224:1227	able	1224:1227	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	8	77	theme	nerve	1206:1210	arg1	conduit					1212:1218	the nerve conduit	1202:1218	the nerve conduit	1202:1218	After 10 mm defect in rat sciatic nerve was bridged with the composite bioactive chitosan-based nerve conduit, the nerve conduit was able to effectively promote axonal regeneration and played a positive role in inducing nerve regeneration and functional recovery.					
36558171	1	78	theme	peripheral	202:211	arg1	defects					219:225	peripheral nerve defects	202:225	peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	202:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
36558171	0	79	theme	Chitosan-Based	65:78	arg1	Conduit					86:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit	29:92	Nerve Regeneration Effect of a Composite Bioactive Carboxymethyl Chitosan-Based Nerve Conduit with a Radial Texture.					
36558171	3	80	theme	linked	579:584	arg1	C-CM-CTS					610:617	C-CM-CTS	610:617	C-CM-CTS	610:617	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	80	theme	linked	579:584	arg1	chitosan					600:607	inner porous cross linked carboxymethyl chitosan	560:607	inner porous cross linked carboxymethyl chitosan (C-CM-CTS)	560:618	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	3	81	theme	outer	483:487	arg1	scaffold					507:514	outer warp-knitted tube scaffold	483:514	outer warp-knitted tube scaffold made from medical-grade chitosan fiber	483:553	Herein, a composite, bioactive chitosan based nerve conduit, consisting of outer warp-knitted tube scaffold made from medical-grade chitosan fiber, and inner porous cross linked carboxymethyl chitosan (C-CM-CTS) sponge with radial texture was developed.					
36558171	6	82	theme	damage	932:937	arg1	fibroblast					889:898	fibroblast	889:898	fibroblast	889:898	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	6	82	theme	damage	932:937	arg1	inhibition					908:917	its inhibition	904:917	its inhibition of oxidative damage to Schwann cells	904:954	An in vitro study of CM-CTS revealed its satisfying biocompatibility with fibroblast and its inhibition of oxidative damage to Schwann cells.					
36558171	1	83	theme	nerve	213:217	arg1	defects					219:225	peripheral nerve defects	202:225	peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties	202:291	Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties.					
37301354	5	0	theme	mechanical	775:784	arg1	properties					786:795	mechanical properties	775:795	mechanical properties	775:795	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	6	1	theme	excellent	949:957	arg1	effects					1000:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	7	2	theme	oral	1045:1048	arg1	patches					1056:1062	commercial oral ulcer patches	1034:1062	commercial oral ulcer patches	1034:1062	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	2	3	theme	probiotics	347:356	arg1	ability					336:342	the ability	332:342	the ability of probiotics to promote ulcer healing	332:381	Fucoidan (FD), a marine prebiotic, may further enhance the ability of probiotics to promote ulcer healing.					
37301354	1	4	theme	repair	269:274	arg1	regulation					210:219	the regulation	206:219	the regulation of immune function	206:238	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	4	theme	repair	269:274	arg1	modulation					248:257	the modulation	244:257	the modulation of tissue repair	244:274	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	7	5	theme	epithelial	1196:1205	arg1	formation					1207:1215	epithelial formation	1196:1215	epithelial formation	1196:1215	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	3	6	theme	ulcer	488:492	arg1	healing					494:500	oral ulcer healing	483:500	oral ulcer healing owing to the wet and highly dynamic environment	483:548	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	5	7	theme	wet-tissue	732:741	arg1	adhesion					743:750	remarkable wet-tissue adhesion	721:750	remarkable wet-tissue adhesion	721:750	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	3	8	theme	wet	515:517	arg1	environment					538:548	the wet and highly dynamic environment	511:548	the wet and highly dynamic environment	511:548	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	3	9	theme	dynamic	530:536	arg1	environment					538:548	the wet and highly dynamic environment	511:548	the wet and highly dynamic environment	511:548	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	6	10	theme	composite	920:928	arg1	hydrogel					930:937	the composite hydrogel	916:937	the composite hydrogel	916:937	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	3	11	theme	oral	483:486	arg1	healing					494:500	oral ulcer healing	483:500	oral ulcer healing owing to the wet and highly dynamic environment	483:548	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	8	12	theme	hydrogel	1352:1359	arg1	patch					1361:1365	this novel composite hydrogel patch	1331:1365	this novel composite hydrogel patch	1331:1365	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	8	13	theme	composite	1342:1350	arg1	patch					1361:1365	this novel composite hydrogel patch	1331:1365	this novel composite hydrogel patch	1331:1365	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	5	14	theme	suitable	753:760	arg1	swelling					762:769	suitable swelling	753:769	suitable swelling	753:769	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	7	15	theme	cell	1171:1174	arg1	migration					1176:1184	cell migration	1171:1184	cell migration	1171:1184	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	1	16	from	cavity	142:147	arg1	located					122:128	located	122:128	located	122:128	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	0	17	theme	calcium	17:23	arg1	alginate/fucoidan					25:41	Probiotic-loaded calcium alginate/fucoidan	0:41	Probiotic-loaded calcium alginate/fucoidan	0:41	Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing.					
37301354	3	18	attach	attached	423:430	arg2	probiotics					408:417	probiotics	408:417	probiotics	408:417	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	3	18	attach	attached	423:430	arg2	FD					401:402	FD	401:402	FD	401:402	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	3	18	attach	attached	423:430	arg1	cavity					444:449	the oral cavity	435:449	the oral cavity	435:449	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	1	19	theme	beneficial	102:111	arg1	Probiotics					87:96	Probiotics	87:96	Probiotics	87:96	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	19	theme	beneficial	102:111	arg1	bacteria					113:120	beneficial bacteria	102:120	beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair	102:274	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	7	20	dep	show	1085:1088	arg1	facilitating					1267:1278	facilitating	1267:1278	facilitating neovascularization	1267:1297	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	7	20	dep	show	1085:1088	arg1	inducing					1187:1194	inducing	1187:1194	inducing epithelial formation and orderly collagen fiber deposition	1187:1253	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	4	21	theme	oral	665:668	arg1	patches					676:682	bioactive oral ulcer patches	655:682	bioactive oral ulcer patches	655:682	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	0	22	theme	Probiotic-loaded	0:15	arg1	alginate/fucoidan					25:41	Probiotic-loaded calcium alginate/fucoidan	0:41	Probiotic-loaded calcium alginate/fucoidan	0:41	Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing.					
37301354	7	23	theme	collagen	1229:1236	arg1	deposition					1244:1253	orderly collagen fiber deposition	1221:1253	orderly collagen fiber deposition	1221:1253	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	2	24	theme	ulcer	369:373	arg1	healing					375:381	ulcer healing	369:381	ulcer healing	369:381	Fucoidan (FD), a marine prebiotic, may further enhance the ability of probiotics to promote ulcer healing.					
37301354	5	25	theme	excellent	831:839	arg1	durability					849:858	excellent storage durability	831:858	excellent storage durability	831:858	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	5	26	theme	well-shaped	689:699	arg1	hydrogels					701:709	The well-shaped hydrogels	685:709	The well-shaped hydrogels	685:709	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	1	27	theme	located	122:128	arg1	Probiotics					87:96	Probiotics	87:96	Probiotics	87:96	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	27	theme	located	122:128	arg1	bacteria					113:120	beneficial bacteria	102:120	beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair	102:274	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	5	28	theme	storage	841:847	arg1	durability					849:858	excellent storage durability	831:858	excellent storage durability	831:858	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	2	29	theme	marine	294:299	arg1	prebiotic					301:309	a marine prebiotic	292:309	a marine prebiotic	292:309	Fucoidan (FD), a marine prebiotic, may further enhance the ability of probiotics to promote ulcer healing.					
37301354	2	29	theme	marine	294:299	arg1	Fucoidan					277:284	Fucoidan	277:284	Fucoidan (FD)	277:289	Fucoidan (FD), a marine prebiotic, may further enhance the ability of probiotics to promote ulcer healing.					
37301354	1	30	theme	immune	224:229	arg1	function					231:238	immune function	224:238	immune function	224:238	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	7	31	theme	orderly	1221:1227	arg1	deposition					1244:1253	orderly collagen fiber deposition	1221:1253	orderly collagen fiber deposition	1221:1253	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	8	32	theme	ulcerations	1422:1432	arg1	treatment					1404:1412	the treatment	1400:1412	the treatment of oral ulcerations	1400:1432	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	6	33	theme	biological	880:889	arg1	assays					891:896	in vitro biological assays	871:896	in vitro biological assays	871:896	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	4	34	theme	bioactive	655:663	arg1	patches					676:682	bioactive oral ulcer patches	655:682	bioactive oral ulcer patches	655:682	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	1	35	theme	function	231:238	arg1	regulation					210:219	the regulation	206:219	the regulation of immune function	206:238	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	35	theme	function	231:238	arg1	modulation					248:257	the modulation	244:257	the modulation of tissue repair	244:274	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	5	36	theme	sustained	798:806	arg1	release					818:824	sustained probiotic release	798:824	sustained probiotic release	798:824	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	5	37	theme	remarkable	721:730	arg1	adhesion					743:750	remarkable wet-tissue adhesion	721:750	remarkable wet-tissue adhesion	721:750	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	8	38	theme	great	1380:1384	arg1	potential					1386:1394	great potential	1380:1394	great potential for the treatment of oral ulcerations	1380:1432	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	7	39	theme	fiber	1238:1242	arg1	deposition					1244:1253	orderly collagen fiber deposition	1221:1253	orderly collagen fiber deposition	1221:1253	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	3	40	theme	oral	439:442	arg1	cavity					444:449	the oral cavity	435:449	the oral cavity	435:449	However, neither FD nor probiotics are attached to the oral cavity and neither are well-suited for oral ulcer healing owing to the wet and highly dynamic environment.					
37301354	0	41	theme	ulcer	72:76	arg1	healing					78:84	oral ulcer healing	67:84	oral ulcer healing	67:84	Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing.					
37301354	6	42	dep	in	871:872	arg1	vitro					874:878	vitro	874:878	vitro	874:878	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	6	43	theme	in	871:872	arg1	assays					891:896	in vitro biological assays	871:896	in vitro biological assays	871:896	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	8	44	theme	novel	1336:1340	arg1	patch					1361:1365	this novel composite hydrogel patch	1331:1365	this novel composite hydrogel patch	1331:1365	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	7	45	theme	ulcer	1136:1140	arg1	healing					1142:1148	ulcer healing	1136:1148	ulcer healing	1136:1148	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	0	46	theme	oral	67:70	arg1	healing					78:84	oral ulcer healing	67:84	oral ulcer healing	67:84	Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing.					
37301354	6	47	theme	antimicrobial	986:998	arg1	effects					1000:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	1	48	theme	oral	137:140	arg1	cavity					142:147	the oral cavity	133:147	the oral cavity	133:147	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	49	from	located	122:128	arg1	cavity					142:147	the oral cavity	133:147	the oral cavity	133:147	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	7	50	theme	superior	1090:1097	arg1	capability					1111:1120	superior therapeutic capability	1090:1120	superior therapeutic capability	1090:1120	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	7	51	theme	bioactive	1065:1073	arg1	hydrogels					1075:1083	bioactive hydrogels	1065:1083	bioactive hydrogels	1065:1083	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	4	52	theme	calcium	583:589	arg1	hydrogels					619:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	7	53	theme	therapeutic	1099:1109	arg1	capability					1111:1120	superior therapeutic capability	1090:1120	superior therapeutic capability	1090:1120	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	7	54	theme	ulcer	1050:1054	arg1	patches					1056:1062	commercial oral ulcer patches	1034:1062	commercial oral ulcer patches	1034:1062	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	4	55	theme	ulcer	670:674	arg1	patches					676:682	bioactive oral ulcer patches	655:682	bioactive oral ulcer patches	655:682	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	4	56	theme	probiotic-loaded	566:581	arg1	hydrogels					619:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	8	57	theme	oral	1417:1420	arg1	ulcerations					1422:1432	oral ulcerations	1417:1432	oral ulcerations	1417:1432	These results demonstrate that this novel composite hydrogel patch demonstrates great potential for the treatment of oral ulcerations.					
37301354	4	58	theme	composite	609:617	arg1	hydrogels					619:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	5	59	theme	probiotic	808:816	arg1	release					818:824	sustained probiotic release	798:824	sustained probiotic release	798:824	The well-shaped hydrogels exhibited remarkable wet-tissue adhesion, suitable swelling and mechanical properties, sustained probiotic release, and excellent storage durability.					
37301354	6	60	theme	cyto/hemocompatibility	959:980	arg1	effects					1000:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	excellent cyto/hemocompatibility and antimicrobial effects	949:1006	Moreover, in vitro biological assays demonstrated that the composite hydrogel exhibited excellent cyto/hemocompatibility and antimicrobial effects.					
37301354	4	61	theme	alginate/fucoidan	591:607	arg1	hydrogels					619:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	probiotic-loaded calcium alginate/fucoidan composite hydrogels	566:627	In this study, probiotic-loaded calcium alginate/fucoidan composite hydrogels were developed for use as bioactive oral ulcer patches.					
37301354	7	62	theme	commercial	1034:1043	arg1	patches					1056:1062	commercial oral ulcer patches	1034:1062	commercial oral ulcer patches	1034:1062	Importantly, compared to commercial oral ulcer patches, bioactive hydrogels show superior therapeutic capability for promoting ulcer healing in vivo by enhancing cell migration, inducing epithelial formation and orderly collagen fiber deposition, as well as facilitating neovascularization.					
37301354	1	63	theme	antimicrobial	163:175	arg1	properties					177:186	antimicrobial properties	163:186	antimicrobial properties	163:186	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
37301354	1	64	theme	tissue	262:267	arg1	repair					269:274	tissue repair	262:274	tissue repair	262:274	Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial properties and contribute to the regulation of immune function and the modulation of tissue repair.					
35698342	2	0	theme	metal-organic	450:462	arg1	framework					464:472	the metal-organic framework	446:472	the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites	446:528	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	2	0	theme	metal-organic	450:462	arg1	ZIF-8					475:479	ZIF-8	475:479	ZIF-8	475:479	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	3	1	theme	test	661:664	arg1	strip					666:670	a portable disposable test strip	639:670	a portable disposable test strip	639:670	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	4	2	theme	ZIF-8/CS	801:808	arg1	film					817:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	5	3	theme	dual-functional	1082:1096	arg1	sensor					1110:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	5	4	theme	luminescent	1098:1108	arg1	sensor					1110:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	4	5	theme	@	800:800	arg1	film					817:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	0	6	theme	tetracycline	105:116	arg1	adsorption					91:100	adsorption	91:100	adsorption	91:100	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	0	6	theme	tetracycline	105:116	arg1	detection					77:85	detection	77:85	detection	77:85	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	3	7	theme	portable	641:648	arg1	strip					666:670	a portable disposable test strip	639:670	a portable disposable test strip	639:670	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	5	8	theme	pharmaceutical	1195:1208	arg1	analysis					1210:1217	pharmaceutical analysis	1195:1217	pharmaceutical analysis	1195:1217	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	4	9	theme	fluorescence	876:887	arg1	detection					889:897	TC fluorescence detection	873:897	TC fluorescence detection	873:897	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	4	10	theme	hybrid	810:815	arg1	film					817:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	4	11	theme	rapid	903:907	arg1	capability					923:932	rapid decontaminate capability	903:932	rapid decontaminate capability	903:932	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	3	12	with	sensor	629:634	arg1	dual-function					677:689	dual-function	677:689	dual-function	677:689	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	1	13	theme	important	168:176	arg1	class					178:182	an important class	165:182	an important class of emerging contaminants in the environment	165:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	13	theme	important	168:176	arg1	residues					137:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	3	14	theme	@	614:614	arg1	sensor					629:634	a shapable CDs@ZIF-8/CS film sensor	600:634	a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption	600:720	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	5	15	theme	contaminant	1172:1182	arg1	removal					1184:1190	contaminant removal	1172:1190	contaminant removal	1172:1190	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	4	16	theme	CDs	797:799	arg1	film					817:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	5	17	theme	TC	1155:1156	arg1	detection					1158:1166	TC detection	1155:1166	TC detection	1155:1166	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	2	18	theme	@	355:355	arg1	ZIF-8					356:360	a novel CDs@ZIF-8	344:360	a novel CDs@ZIF-8 sensing material	344:377	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	2	19	theme	carbon	423:428	arg1	CDs					436:438	CDs	436:438	CDs	436:438	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	2	19	theme	carbon	423:428	arg1	dots					430:433	luminescent carbon dots	411:433	luminescent carbon dots (CDs)	411:439	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	4	20	theme	TC	873:874	arg1	detection					889:897	TC fluorescence detection	873:897	TC fluorescence detection	873:897	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	4	21	theme	as-prepared	785:795	arg1	film					817:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film	781:820	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	2	22	theme	CDs	352:354	arg1	ZIF-8					356:360	a novel CDs@ZIF-8	344:360	a novel CDs@ZIF-8 sensing material	344:377	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	2	23	theme	luminescent	411:421	arg1	CDs					436:438	CDs	436:438	CDs	436:438	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	2	23	theme	luminescent	411:421	arg1	dots					430:433	luminescent carbon dots	411:433	luminescent carbon dots (CDs)	411:439	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	1	24	theme	detection	274:282	arg1	method					284:289	fast, straightforward, highly sensitive detection method	234:289	fast, straightforward, highly sensitive detection method	234:289	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	4	25	theme	sensing	1044:1050	arg1	application					1052:1062	the practical sensing application	1030:1062	the practical sensing application	1030:1062	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	1	26	theme	emerging	187:194	arg1	contaminants					196:207	emerging contaminants	187:207	emerging contaminants in the environment	187:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	0	27	theme	@	19:19	arg1	sensors					52:58	@ZIF-8/chitosan luminescent film sensors	19:58	@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline	19:116	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	3	28	theme	TC	694:695	arg1	detection					697:705	TC detection	694:705	TC detection	694:705	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	2	29	theme	porous	512:517	arg1	composites					519:528	highly luminescent porous composites	493:528	highly luminescent porous composites	493:528	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	3	30	theme	CDs	611:613	arg1	sensor					629:634	a shapable CDs@ZIF-8/CS film sensor	600:634	a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption	600:720	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	1	31	theme	Tetracycline	119:130	arg1	class					178:182	an important class	165:182	an important class of emerging contaminants in the environment	165:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	31	theme	Tetracycline	119:130	arg1	residues					137:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	32	theme	contaminants	196:207	arg1	class					178:182	an important class	165:182	an important class of emerging contaminants in the environment	165:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	32	theme	contaminants	196:207	arg1	residues					137:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	0	33	theme	film	47:50	arg1	sensors					52:58	@ZIF-8/chitosan luminescent film sensors	19:58	@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline	19:116	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	3	34	theme	detection	697:705	arg1	dual-function					677:689	dual-function	677:689	dual-function	677:689	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	2	35	theme	luminescent	500:510	arg1	composites					519:528	highly luminescent porous composites	493:528	highly luminescent porous composites	493:528	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	1	36	dep	fast	234:237	arg1	straightforward					240:254	straightforward	240:254	straightforward	240:254	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	36	dep	fast	234:237	arg1	sensitive					264:272	sensitive	264:272	sensitive	264:272	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	3	37	theme	secondary	557:565	arg1	contamination					567:579	the secondary contamination	553:579	the secondary contamination caused by powders	553:597	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	4	38	theme	mechanical	984:993	arg1	property					995:1002	robust mechanical property	977:1002	robust mechanical property	977:1002	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	0	39	theme	luminescent	35:45	arg1	sensors					52:58	@ZIF-8/chitosan luminescent film sensors	19:58	@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline	19:116	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	0	40	theme	ZIF-8/chitosan	20:33	arg1	sensors					52:58	@ZIF-8/chitosan luminescent film sensors	19:58	@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline	19:116	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	4	41	theme	optical	951:957	arg1	transmittance					959:971	high optical transmittance	946:971	high optical transmittance	946:971	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	5	42	theme	promising	1126:1134	arg1	practicability					1136:1149	promising practicability	1126:1149	promising practicability for TC detection and contaminant removal	1126:1190	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	3	43	theme	shapable	602:609	arg1	sensor					629:634	a shapable CDs@ZIF-8/CS film sensor	600:634	a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption	600:720	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	3	44	theme	adsorption	711:720	arg1	dual-function					677:689	dual-function	677:689	dual-function	677:689	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	4	45	theme	high	946:949	arg1	transmittance					959:971	high optical transmittance	946:971	high optical transmittance	946:971	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	5	46	theme	paper-based	1070:1080	arg1	sensor					1110:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor	1065:1115	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	4	47	theme	decontaminate	909:921	arg1	capability					923:932	rapid decontaminate capability	903:932	rapid decontaminate capability	903:932	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	1	48	from	environment	216:226	arg1	class					178:182	an important class	165:182	an important class of emerging contaminants in the environment	165:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	1	48	from	environment	216:226	arg1	residues					137:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues	119:144	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	4	49	theme	robust	977:982	arg1	property					995:1002	robust mechanical property	977:1002	robust mechanical property	977:1002	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	1	50	from	contaminants	196:207	arg1	environment					216:226	the environment	212:226	the environment	212:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	4	51	theme	high	836:839	arg1	sensitivity					841:851	the high sensitivity	832:851	the high sensitivity	832:851	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	3	52	theme	ZIF-8/CS	615:622	arg1	sensor					629:634	a shapable CDs@ZIF-8/CS film sensor	600:634	a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption	600:720	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	1	53	from	class	178:182	arg1	environment					216:226	the environment	212:226	the environment	212:226	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35698342	4	54	theme	practical	1034:1042	arg1	application					1052:1062	the practical sensing application	1030:1062	the practical sensing application	1030:1062	The as-prepared CDs@ZIF-8/CS hybrid film exhibited the high sensitivity and selectivity for TC fluorescence detection and rapid decontaminate capability, as well as high optical transmittance and robust mechanical property, which were essential for the practical sensing application.					
35698342	5	55	theme	food	1220:1223	arg1	safety					1225:1230	food safety	1220:1230	food safety	1220:1230	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	3	56	theme	film	624:627	arg1	sensor					629:634	a shapable CDs@ZIF-8/CS film sensor	600:634	a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption	600:720	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	2	57	theme	novel	346:350	arg1	ZIF-8					356:360	a novel CDs@ZIF-8	344:360	a novel CDs@ZIF-8 sensing material	344:377	Herein, a novel CDs@ZIF-8 sensing material was fabricated by encapsulating luminescent carbon dots (CDs) into the metal-organic framework (ZIF-8) to achieve highly luminescent porous composites.					
35698342	3	58	theme	CDs	751:753	arg1	ZIF-8					755:759	CDs@ZIF-8	751:759	CDs@ZIF-8 with chitosan (CS)	751:778	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	0	59	theme	simultaneous	64:75	arg1	detection					77:85	detection	77:85	detection	77:85	Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline.					
35698342	3	60	theme	disposable	650:659	arg1	strip					666:670	a portable disposable test strip	639:670	a portable disposable test strip	639:670	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	3	61	theme	@	754:754	arg1	ZIF-8					755:759	CDs@ZIF-8	751:759	CDs@ZIF-8 with chitosan (CS)	751:778	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	3	62	with	ZIF-8	755:759	arg1	CS					776:777	CS	776:777	CS	776:777	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	3	62	with	ZIF-8	755:759	arg1	chitosan					766:773	chitosan	766:773	chitosan (CS)	766:778	Furthermore, to avoid the secondary contamination caused by powders, a shapable CDs@ZIF-8/CS film sensor as a portable disposable test strip with dual-function of TC detection and adsorption was designed by crosslinking CDs@ZIF-8 with chitosan (CS).					
35698342	5	63	theme	water	1236:1240	arg1	treatment					1242:1250	water treatment	1236:1250	water treatment	1236:1250	This paper-based dual-functional luminescent sensor exhibits promising practicability for TC detection and contaminant removal in pharmaceutical analysis, food safety and water treatment.					
35698342	1	64	theme	fast	234:237	arg1	method					284:289	fast, straightforward, highly sensitive detection method	234:289	fast, straightforward, highly sensitive detection method	234:289	Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed.					
35450652	2	0	theme	coordination	417:428	arg1	compound					430:437	titanium alginate coordination compound	399:437	titanium alginate coordination compound	399:437	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	7	1	theme	high-efficiency	1206:1220	arg1	photocatalysts					1222:1235	high-efficiency photocatalysts	1206:1235	high-efficiency photocatalysts from a polysaccharide-based coordination compound	1206:1285	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	2	2	theme	alginate	408:415	arg1	compound					430:437	titanium alginate coordination compound	399:437	titanium alginate coordination compound	399:437	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	6	3	theme	cyclic	1029:1034	arg1	tests					1036:1040	five cyclic tests	1024:1040	five cyclic tests	1024:1040	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	4	4	theme	optical	769:775	arg1	sensibilization					777:791	the optical sensibilization	765:791	the optical sensibilization	765:791	The carbon mainly existed in the outer layer of TiO2/C composites, contributing to the optical sensibilization.					
35450652	6	5	contain	possessed	936:944	arg2	stability					951:959	high stability	946:959	high stability	946:959	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	6	5	contain	possessed	936:944	arg1	samples					923:929	The samples	919:929	The samples	919:929	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	7	6	from	compound	1147:1154	arg1	photocatalyst					1097:1109	photocatalyst	1097:1109	photocatalyst from titanium-alginate coordination compound	1097:1154	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	7	7	theme	extensible	1172:1181	arg1	approach					1183:1190	an extensible approach	1169:1190	an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound	1169:1285	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	2	8	theme	photocatalytic	457:470	arg1	performance					472:482	their photocatalytic performance	451:482	their photocatalytic performance against methylene blue (MB)	451:510	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	2	9	theme	simulated	518:526	arg1	irradiation					537:547	simulated sunlight irradiation	518:547	simulated sunlight irradiation	518:547	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	6	10	theme	high	946:949	arg1	stability					951:959	high stability	946:959	high stability	946:959	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	4	11	theme	TiO2/C	730:735	arg1	composites					737:746	TiO2/C composites	730:746	TiO2/C composites	730:746	The carbon mainly existed in the outer layer of TiO2/C composites, contributing to the optical sensibilization.					
35450652	7	12	theme	polysaccharide-based	1244:1263	arg1	compound					1278:1285	a polysaccharide-based coordination compound	1242:1285	a polysaccharide-based coordination compound	1242:1285	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	7	13	theme	titanium-alginate	1116:1132	arg1	compound					1147:1154	titanium-alginate coordination compound	1116:1154	titanium-alginate coordination compound	1116:1154	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	1	14	theme	rapid	220:224	arg1	recombination					226:238	rapid recombination	220:238	rapid recombination of photogenerated electrons and wide bandgap	220:283	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	0	15	theme	titanium-alginate	37:53	arg1	compound					68:75	titanium-alginate coordination compound	37:75	titanium-alginate coordination compound	37:75	TiO2/carbonaceous nanocomposite from titanium-alginate coordination compound.					
35450652	7	16	theme	coordination	1134:1145	arg1	compound					1147:1154	titanium-alginate coordination compound	1116:1154	titanium-alginate coordination compound	1116:1154	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	1	17	theme	eco-friendly	131:142	arg1	photocatalysts					144:157	eco-friendly photocatalysts	131:157	eco-friendly photocatalysts	131:157	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	2	18	theme	blue	502:505	arg1	methylene					492:500	methylene blue	492:505	methylene blue (MB)	492:510	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	2	18	theme	blue	502:505	arg1	MB					508:509	MB	508:509	MB	508:509	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	5	19	theme	sample	837:842	arg1	TiO2/C-20					844:852	sample TiO2/C-20	837:852	sample TiO2/C-20	837:852	As a result, the degradation efficiency of sample TiO2/C-20 to MB could reach 97.47% within 15 min under simulated sunlight.					
35450652	6	20	theme	photodegradation	995:1010	arg1	ratio					1012:1016	photodegradation ratio	995:1016	photodegradation ratio	995:1016	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	3	21	theme	N2	647:648	arg1	analysis					672:679	N2 adsorption-desorption analysis	647:679	N2 adsorption-desorption analysis	647:679	The resultant nanocomposites were characterized by FT-IR, XPS, XRD, SEM-EDS, TG-DTG, UV-DRS, and N2 adsorption-desorption analysis.					
35450652	1	22	theme	photogenerated	243:256	arg1	electrons					258:266	photogenerated electrons	243:266	photogenerated electrons	243:266	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	0	23	theme	coordination	55:66	arg1	compound					68:75	titanium-alginate coordination compound	37:75	titanium-alginate coordination compound	37:75	TiO2/carbonaceous nanocomposite from titanium-alginate coordination compound.					
35450652	5	24	theme	TiO2/C-20	844:852	arg1	efficiency					823:832	the degradation efficiency	807:832	the degradation efficiency of sample TiO2/C-20 to MB	807:858	As a result, the degradation efficiency of sample TiO2/C-20 to MB could reach 97.47% within 15 min under simulated sunlight.					
35450652	7	25	from	compound	1278:1285	arg1	photocatalysts					1222:1235	high-efficiency photocatalysts	1206:1235	high-efficiency photocatalysts from a polysaccharide-based coordination compound	1206:1285	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	3	26	theme	adsorption-desorption	650:670	arg1	analysis					672:679	N2 adsorption-desorption analysis	647:679	N2 adsorption-desorption analysis	647:679	The resultant nanocomposites were characterized by FT-IR, XPS, XRD, SEM-EDS, TG-DTG, UV-DRS, and N2 adsorption-desorption analysis.					
35450652	1	27	theme	electrons	258:266	arg1	recombination					226:238	rapid recombination	220:238	rapid recombination of photogenerated electrons and wide bandgap	220:283	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	2	28	theme	titanium	399:406	arg1	compound					430:437	titanium alginate coordination compound	399:437	titanium alginate coordination compound	399:437	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	2	29	theme	sunlight	528:535	arg1	irradiation					537:547	simulated sunlight irradiation	518:547	simulated sunlight irradiation	518:547	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	6	30	theme	%	980:980	arg1	reduction					982:990	the 0.72% reduction	972:990	the 0.72% reduction in photodegradation ratio after five cyclic tests	972:1040	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	7	31	theme	present	1047:1053	arg1	study					1055:1059	The present study	1043:1059	The present study	1043:1059	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	7	32	theme	coordination	1265:1276	arg1	compound					1278:1285	a polysaccharide-based coordination compound	1242:1285	a polysaccharide-based coordination compound	1242:1285	The present study proved the feasibility of preparing photocatalyst from titanium-alginate coordination compound and provided an extensible approach for preparing high-efficiency photocatalysts from a polysaccharide-based coordination compound.					
35450652	2	33	theme	TiO2/carbonaceous	311:327	arg1	TiO2/C					345:350	TiO2/C	345:350	TiO2/C	345:350	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	2	33	theme	TiO2/carbonaceous	311:327	arg1	photocatalysts					329:342	high-efficient TiO2/carbonaceous photocatalysts	296:342	high-efficient TiO2/carbonaceous photocatalysts (TiO2/C)	296:351	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	3	34	theme	resultant	554:562	arg1	nanocomposites					564:577	The resultant nanocomposites	550:577	The resultant nanocomposites	550:577	The resultant nanocomposites were characterized by FT-IR, XPS, XRD, SEM-EDS, TG-DTG, UV-DRS, and N2 adsorption-desorption analysis.					
35450652	6	35	from	reduction	982:990	arg1	ratio					1012:1016	photodegradation ratio	995:1016	photodegradation ratio	995:1016	The samples also possessed high stability, proved by the 0.72% reduction in photodegradation ratio after five cyclic tests.					
35450652	2	36	theme	high-efficient	296:309	arg1	TiO2/C					345:350	TiO2/C	345:350	TiO2/C	345:350	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	2	36	theme	high-efficient	296:309	arg1	photocatalysts					329:342	high-efficient TiO2/carbonaceous photocatalysts	296:342	high-efficient TiO2/carbonaceous photocatalysts (TiO2/C)	296:351	To obtain high-efficient TiO2/carbonaceous photocatalysts (TiO2/C), we prepared the nanocomposite by carbonizing titanium alginate coordination compound and studied their photocatalytic performance against methylene blue (MB) under simulated sunlight irradiation.					
35450652	1	37	theme	inherent	168:175	arg1	defects					177:183	the inherent defects	164:183	the inherent defects	164:183	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	1	38	theme	wide	272:275	arg1	bandgap					277:283	wide bandgap	272:283	wide bandgap	272:283	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	5	39	theme	simulated	899:907	arg1	sunlight					909:916	simulated sunlight	899:916	simulated sunlight	899:916	As a result, the degradation efficiency of sample TiO2/C-20 to MB could reach 97.47% within 15 min under simulated sunlight.					
35450652	4	40	theme	outer	715:719	arg1	layer					721:725	the outer layer	711:725	the outer layer of TiO2/C composites	711:746	The carbon mainly existed in the outer layer of TiO2/C composites, contributing to the optical sensibilization.					
35450652	1	41	theme	bandgap	277:283	arg1	recombination					226:238	rapid recombination	220:238	rapid recombination of photogenerated electrons and wide bandgap	220:283	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	5	42	theme	degradation	811:821	arg1	efficiency					823:832	the degradation efficiency	807:832	the degradation efficiency of sample TiO2/C-20 to MB	807:858	As a result, the degradation efficiency of sample TiO2/C-20 to MB could reach 97.47% within 15 min under simulated sunlight.					
35450652	1	43	theme	TiO2-based	78:87	arg1	materials					89:97	TiO2-based materials	78:97	TiO2-based materials	78:97	TiO2-based materials have been developing rapidly as eco-friendly photocatalysts, but the inherent defects limited their application, such as rapid recombination of photogenerated electrons and wide bandgap.					
35450652	4	44	theme	composites	737:746	arg1	layer					721:725	the outer layer	711:725	the outer layer of TiO2/C composites	711:746	The carbon mainly existed in the outer layer of TiO2/C composites, contributing to the optical sensibilization.					
37182966	5	0	theme	Such	1108:1111	arg1	lignin/chitosan					1123:1137	Such developed lignin/chitosan	1108:1137	Such developed lignin/chitosan with both components from biomass	1108:1171	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	4	1	theme	composite	877:885	arg1	film					887:890	the composite film	873:890	the composite film	873:890	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	1	2	theme	promising	153:161	arg1	chitosan					139:146	chitosan	139:146	chitosan	139:146	As a natural green polymer, chitosan is a promising material for plastic replacement.					
37182966	1	2	theme	promising	153:161	arg1	material					163:170	a promising material	151:170	a promising material for plastic replacement	151:194	As a natural green polymer, chitosan is a promising material for plastic replacement.					
37182966	5	3	with	lignin/chitosan	1123:1137	arg1	components					1149:1158	both components	1144:1158	both components	1144:1158	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	3	4	theme	chitosan	845:852	arg1	film					854:857	the pure chitosan film	836:857	the pure chitosan film	836:857	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	0	5	theme	food	92:95	arg1	preservation					97:108	food preservation	92:108	food preservation	92:108	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	5	6	theme	developed	1113:1121	arg1	lignin/chitosan					1123:1137	Such developed lignin/chitosan	1108:1137	Such developed lignin/chitosan with both components from biomass	1108:1171	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	3	7	theme	high-performance	536:551	arg1	film					579:582	a high-performance lignin/chitosan composite film	534:582	a high-performance lignin/chitosan composite film	534:582	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	8	theme	oxygen	958:963	arg1	permeability					965:976	low oxygen permeability	954:976	low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa))	954:1003	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	2	9	theme	improved	303:310	arg1	strength					312:319	the improved strength	299:319	the improved strength of chitosan-based materials	299:347	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	5	10	theme	plastic	1212:1218	arg1	replacement					1220:1230	plastic replacement	1212:1230	plastic replacement	1212:1230	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	3	11	theme	hydrogen	631:638	arg1	interaction					661:671	electrostatic interaction	647:671	electrostatic interaction	647:671	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	11	theme	hydrogen	631:638	arg1	etc.					674:677	etc.	674:677	etc.	674:677	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	11	theme	hydrogen	631:638	arg1	bonds					640:644	hydrogen bonds	631:644	hydrogen bonds	631:644	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	12	theme	sacrificial	600:610	arg1	conjoined-network					612:628	sacrificial conjoined-network	600:628	sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.)	600:678	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	13	theme	pure	840:843	arg1	film					854:857	the pure chitosan film	836:857	the pure chitosan film	836:857	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	14	with	stability	943:951	arg1	change					1047:1052	no negligible change	1033:1052	no negligible change for grape, apple, and cherry tomato after 5-10 days	1033:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	3	15	theme	multiple	446:453	arg1	interactions					468:479	multiple non-covalent interactions	446:479	the existed multiple non-covalent interactions in biosynthesized fibers	434:504	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	16	theme	food	1009:1012	arg1	preservation					1014:1025	food preservation	1009:1025	food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days)	1009:1105	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	4	17	with	preservation	1014:1025	arg1	change					1047:1052	no negligible change	1033:1052	no negligible change for grape, apple, and cherry tomato after 5-10 days	1033:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	2	18	theme	toughness	403:411	arg1	expense					378:384	the expense	374:384	the expense of elongation or toughness	374:411	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	0	19	theme	sacrificial	15:25	arg1	conjoined-network					27:43	Lignin-induced sacrificial conjoined-network	0:43	Lignin-induced sacrificial conjoined-network	0:43	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	5	20	from	biomass	1165:1171	arg1	lignin/chitosan					1123:1137	Such developed lignin/chitosan	1108:1137	Such developed lignin/chitosan with both components from biomass	1108:1171	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	2	21	theme	chitosan-based	324:337	arg1	materials					339:347	chitosan-based materials	324:347	chitosan-based materials	324:347	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	0	22	theme	Lignin-induced	0:13	arg1	conjoined-network					27:43	Lignin-induced sacrificial conjoined-network	0:43	Lignin-induced sacrificial conjoined-network	0:43	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	4	23	with	resistance	923:932	arg1	change					1047:1052	no negligible change	1033:1052	no negligible change for grape, apple, and cherry tomato after 5-10 days	1033:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	3	24	theme	existed	438:444	arg1	interactions					468:479	multiple non-covalent interactions	446:479	the existed multiple non-covalent interactions in biosynthesized fibers	434:504	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	25	theme	negligible	1036:1045	arg1	change					1047:1052	no negligible change	1033:1052	no negligible change for grape, apple, and cherry tomato after 5-10 days	1033:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	4	26	theme	thermal	935:941	arg1	stability					943:951	thermal stability	935:951	thermal stability	935:951	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	3	27	theme	electrostatic	647:659	arg1	interaction					661:671	electrostatic interaction	647:671	electrostatic interaction	647:671	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	27	theme	electrostatic	647:659	arg1	bonds					640:644	hydrogen bonds	631:644	hydrogen bonds	631:644	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	28	theme	biosynthesized	484:497	arg1	fibers					499:504	biosynthesized fibers	484:504	biosynthesized fibers	484:504	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	29	dep	permeability	965:976	arg1	m2·24h‧0.1 MPa					988:1001	m2·24h‧0.1 MPa	988:1001	m2·24h‧0.1 MPa	988:1001	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	4	29	dep	permeability	965:976	arg1	3.9 cm3/					979:986	3.9 cm3/	979:986	3.9 cm3/(m2·24h‧0.1 MPa)	979:1002	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	1	30	theme	natural	116:122	arg1	polymer					130:136	a natural green polymer	114:136	a natural green polymer	114:136	As a natural green polymer, chitosan is a promising material for plastic replacement.					
37182966	3	31	dep	conjoined-network	612:628	arg1	interaction					661:671	electrostatic interaction	647:671	electrostatic interaction	647:671	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	31	dep	conjoined-network	612:628	arg1	etc.					674:677	etc.	674:677	etc.	674:677	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	31	dep	conjoined-network	612:628	arg1	bonds					640:644	hydrogen bonds	631:644	hydrogen bonds	631:644	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	5	32	theme	promising	1186:1194	arg1	alternative					1196:1206	a promising alternative	1184:1206	a promising alternative for plastic replacement	1184:1230	Such developed lignin/chitosan with both components from biomass represents a promising alternative for plastic replacement.					
37182966	3	33	theme	impressive	701:710	arg1	enhancement					712:722	an impressive enhancement	698:722	an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3)	698:801	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	2	34	theme	elongation	389:398	arg1	expense					378:384	the expense	374:384	the expense of elongation or toughness	374:411	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	0	35	theme	strong	53:58	arg1	membrane					79:86	strong and tough chitosan membrane	53:86	strong and tough chitosan membrane	53:86	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	3	36	from	interactions	468:479	arg1	fibers					499:504	biosynthesized fibers	484:504	biosynthesized fibers	484:504	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	0	37	theme	chitosan	70:77	arg1	membrane					79:86	strong and tough chitosan membrane	53:86	strong and tough chitosan membrane	53:86	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	4	38	theme	excellent	910:918	arg1	resistance					923:932	excellent UV resistance	910:932	excellent UV resistance	910:932	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	1	39	theme	green	124:128	arg1	polymer					130:136	a natural green polymer	114:136	a natural green polymer	114:136	As a natural green polymer, chitosan is a promising material for plastic replacement.					
37182966	0	40	theme	tough	64:68	arg1	membrane					79:86	strong and tough chitosan membrane	53:86	strong and tough chitosan membrane	53:86	Lignin-induced sacrificial conjoined-network enabled strong and tough chitosan membrane for food preservation.					
37182966	3	41	theme	tensile	727:733	arg1	50.2 MPa					745:752	50.2 MPa	745:752	50.2 MPa	745:752	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	41	theme	tensile	727:733	arg1	strength					735:742	tensile strength	727:742	tensile strength (50.2 MPa)	727:753	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	2	42	theme	exclusive	219:227	arg1	strength					229:236	strength	229:236	strength	229:236	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	2	43	theme	commercial	271:280	arg1	application					282:292	its commercial application	267:292	its commercial application	267:292	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	4	44	theme	UV	920:921	arg1	resistance					923:932	excellent UV resistance	910:932	excellent UV resistance	910:932	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	2	45	theme	materials	339:347	arg1	strength					312:319	the improved strength	299:319	the improved strength of chitosan-based materials	299:347	However, the mutually exclusive strength and toughness severely limit its commercial application, and the improved strength of chitosan-based materials is typically achieved at the expense of elongation or toughness.					
37182966	4	46	theme	cherry	1076:1081	arg1	tomato					1083:1088	cherry tomato	1076:1088	cherry tomato after 5-10 days	1076:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	3	47	theme	non-covalent	455:466	arg1	interactions					468:479	multiple non-covalent interactions	446:479	the existed multiple non-covalent interactions in biosynthesized fibers	434:504	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	%					773:773	73.6 %	768:773	73.6 %	768:773	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	2.7 MJ/m3					792:800	2.7 MJ/m3	792:800	2.7 MJ/m3	792:800	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	50.2 MPa					745:752	50.2 MPa	745:752	50.2 MPa	745:752	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	toughness					781:789	toughness	781:789	toughness (2.7 MJ/m3)	781:801	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	elongation					756:765	elongation	756:765	elongation (73.6 %)	756:774	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	3	48	from	enhancement	712:722	arg1	strength					735:742	tensile strength	727:742	tensile strength (50.2 MPa)	727:753	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	49	with	permeability	965:976	arg1	change					1047:1052	no negligible change	1033:1052	no negligible change for grape, apple, and cherry tomato after 5-10 days	1033:1104	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
37182966	3	50	theme	lignin/chitosan	553:567	arg1	film					579:582	a high-performance lignin/chitosan composite film	534:582	a high-performance lignin/chitosan composite film	534:582	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	1	51	theme	plastic	176:182	arg1	replacement					184:194	plastic replacement	176:194	plastic replacement	176:194	As a natural green polymer, chitosan is a promising material for plastic replacement.					
37182966	3	52	theme	composite	569:577	arg1	film					579:582	a high-performance lignin/chitosan composite film	534:582	a high-performance lignin/chitosan composite film	534:582	Herein, inspired by the existed multiple non-covalent interactions in biosynthesized fibers, we successfully fabricated a high-performance lignin/chitosan composite film by constructing sacrificial conjoined-network (hydrogen bonds, electrostatic interaction, etc.), which results in an impressive enhancement in tensile strength (50.2 MPa), elongation (73.6 %), and toughness (2.7 MJ/m3) simultaneously, much superior to the pure chitosan film.					
37182966	4	53	theme	low	954:956	arg1	permeability					965:976	low oxygen permeability	954:976	low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa))	954:1003	In addition, the composite film also demonstrates excellent UV resistance, thermal stability, low oxygen permeability (3.9 cm3/(m2·24h‧0.1 MPa)) and food preservation (with no negligible change for grape, apple, and cherry tomato after 5-10 days).					
36364136	1	0	theme	imprinted	322:330	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	0	1	theme	Bovine	182:187	arg1	Albumin					195:201	Bovine Serum Albumin	182:201	Bovine Serum Albumin	182:201	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	2	2	theme	calcium	735:741	arg1	alginate					743:750	calcium alginate	735:750	calcium alginate	735:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	0	3	theme	Liquid	78:83	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	1	4	theme	poly	332:335	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	2	5	theme	higher	553:558	arg1	KPa					536:538	up to 90.00 KPa	524:538	up to 90.00 KPa	524:538	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	5	theme	higher	553:558	arg1	times					547:551	30.30 times	541:551	30.30 times higher than the poly (ionic liquid) membrane without calcium alginate	541:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	3	6	theme	proteins	884:891	arg1	transport					871:879	effective mass transport	856:879	effective mass transport of proteins	856:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	5	7	contain	had	1050:1052	arg1	MICM					1040:1043	MICM	1040:1043	MICM	1040:1043	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	5	7	contain	had	1050:1052	arg2	recognition					1085:1095	good selective and competitive recognition	1054:1095	good selective and competitive recognition	1054:1095	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	4	8	theme	high	925:928	arg1	capacity					941:948	a very high adsorption capacity	918:948	a very high adsorption capacity of 485.87 mg g-1	918:965	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	1	9	theme	imprinting	252:261	arg1	efficiency					263:272	imprinting efficiency	252:272	imprinting efficiency	252:272	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	0	10	theme	Alginate	94:101	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	3	11	contain	had	762:764	arg1	MICM					757:760	The MICM	753:760	The MICM	753:760	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	3	11	contain	had	762:764	arg2	ratio					786:790	a very high welling ratio	766:790	a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins	766:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	0	12	theme	Albumin	195:201	arg1	Separation					168:177	the Separation	164:177	the Separation of Bovine Serum Albumin	164:201	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	6	13	theme	potential	1185:1193	arg1	method					1195:1200	a potential method	1183:1200	a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency	1183:1311	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	0	14	theme	/Calcium	85:92	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	0	15	theme	Serum	189:193	arg1	Albumin					195:201	Bovine Serum Albumin	182:201	Bovine Serum Albumin	182:201	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	0	16	theme	Cryogel	113:119	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	4	17	theme	485.87	953:958	arg1	mg					960:961	mg	960:961	mg	960:961	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	2	18	theme	ionic	575:579	arg1	membrane					589:596	the poly (ionic liquid) membrane	565:596	the poly (ionic liquid) membrane without calcium alginate	565:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	19	theme	liquid	581:586	arg1	membrane					589:596	the poly (ionic liquid) membrane	565:596	the poly (ionic liquid) membrane without calcium alginate	565:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	20	theme	8.28	671:674	arg1	%					668:668	up to 93.70%	657:668	up to 93.70%	657:668	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	20	theme	8.28	671:674	arg1	times					676:680	8.28 times	671:680	8.28 times higher than the poly (ionic liquid) membrane without calcium alginate	671:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	0	21	theme	Composite	103:111	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	1	22	dep	albumin	296:302	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	6	23	theme	high	1262:1265	arg1	strength					1278:1285	high mechanical strength	1262:1285	high mechanical strength	1262:1285	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	4	24	theme	concentration	1008:1020	arg1	mL-1					988:991	20 °C and 0.66 mg mL-1	970:991	20 °C and 0.66 mg mL-1 of the initial concentration of BSA	970:1027	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	5	25	theme	good	1054:1057	arg1	recognition					1085:1095	good selective and competitive recognition	1054:1095	good selective and competitive recognition	1054:1095	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	2	26	dep	93.70	663:667	arg1	to					660:661	to	660:661	to	660:661	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	27	theme	excellent	476:484	arg1	strength					497:504	excellent mechanical strength	476:504	excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate	476:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	28	theme	tensile	435:441	arg1	test					443:446	the tensile test	431:446	the tensile test	431:446	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	1	29	theme	/calcium	350:357	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	2	30	theme	poly	569:572	arg1	membrane					589:596	the poly (ionic liquid) membrane	565:596	the poly (ionic liquid) membrane without calcium alginate	565:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	31	dep	90.00	530:534	arg1	to					527:528	to	527:528	to	527:528	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	4	32	dep	mL-1	988:991	arg1	mg					985:986	mg	985:986	mg	985:986	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	1	33	dep	poly	332:335	arg1	liquid					343:348	liquid	343:348	liquid	343:348	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	2	34	theme	poly	698:701	arg1	membrane					718:725	the poly (ionic liquid) membrane	694:725	the poly (ionic liquid) membrane without calcium alginate	694:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	1	35	theme	novel	277:281	arg1	MICM					396:399	MICM	396:399	MICM	396:399	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	35	theme	novel	277:281	arg1	BSA					305:307	BSA	305:307	BSA	305:307	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	35	theme	novel	277:281	arg1	albumin					296:302	a novel bovine serum albumin	275:302	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	2	36	theme	calcium	606:612	arg1	alginate					614:621	calcium alginate	606:621	calcium alginate	606:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	4	37	theme	mg	960:961	arg1	g-1					963:965	485.87 mg g-1	953:965	485.87 mg g-1	953:965	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	6	38	theme	mechanical	1267:1276	arg1	strength					1278:1285	high mechanical strength	1262:1285	high mechanical strength	1262:1285	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	1	39	theme	bovine	283:288	arg1	MICM					396:399	MICM	396:399	MICM	396:399	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	39	theme	bovine	283:288	arg1	BSA					305:307	BSA	305:307	BSA	305:307	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	39	theme	bovine	283:288	arg1	albumin					296:302	a novel bovine serum albumin	275:302	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	5	40	theme	potential	1120:1128	arg1	utility					1130:1136	potential utility	1120:1136	potential utility	1120:1136	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	1	41	theme	alginate	359:366	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	3	42	theme	macropore	808:816	arg1	porosity					818:825	macropore porosity	808:825	macropore porosity	808:825	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	3	43	theme	porosity	818:825	arg1	ratio					786:790	a very high welling ratio	766:790	a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins	766:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	2	44	theme	test	443:446	arg1	results					420:426	The results	416:426	The results of the tensile test	416:446	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	1	45	theme	serum	290:294	arg1	MICM					396:399	MICM	396:399	MICM	396:399	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	45	theme	serum	290:294	arg1	BSA					305:307	BSA	305:307	BSA	305:307	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	1	45	theme	serum	290:294	arg1	albumin					296:302	a novel bovine serum albumin	275:302	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	0	46	theme	Mechanical	140:149	arg1	Strength					151:158	High Mechanical Strength	135:158	High Mechanical Strength for the Separation of Bovine Serum Albumin	135:201	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	1	47	theme	composite	368:376	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	6	48	theme	imprinting	1291:1300	arg1	efficiency					1302:1311	imprinting efficiency	1291:1311	imprinting efficiency	1291:1311	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	2	49	theme	higher	682:687	arg1	%					668:668	up to 93.70%	657:668	up to 93.70%	657:668	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	49	theme	higher	682:687	arg1	times					676:680	8.28 times	671:680	8.28 times higher than the poly (ionic liquid) membrane without calcium alginate	671:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	0	50	theme	Protein	36:42	arg1	Characterization					16:31	Characterization	16:31	Characterization	16:31	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	0	50	theme	Protein	36:42	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	0	51	theme	High	135:138	arg1	Strength					151:158	High Mechanical Strength	135:158	High Mechanical Strength for the Separation of Bovine Serum Albumin	135:201	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	1	52	theme	cryogel	378:384	arg1	membrane					386:393	molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane	310:393	a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM)	275:400	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	3	53	theme	%	802:802	arg1	ratio					786:790	a very high welling ratio	766:790	a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins	766:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	0	54	theme	Poly	66:69	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	6	55	theme	protein-imprinted	1217:1233	arg1	membrane					1243:1250	the protein-imprinted cryogel membrane	1213:1250	the protein-imprinted cryogel membrane	1213:1250	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	2	56	theme	it	642:643	arg1	elongation					628:637	the elongation	624:637	the elongation of it	624:643	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	5	57	theme	competitive	1073:1083	arg1	recognition					1085:1095	good selective and competitive recognition	1054:1095	good selective and competitive recognition	1054:1095	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	4	58	dep	mg	985:986	arg1	0.66					980:983	0.66	980:983	0.66	980:983	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	4	58	dep	mg	985:986	arg1	°C					973:974	°C	973:974	°C	973:974	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	4	59	contain	had	914:916	arg2	capacity					941:948	a very high adsorption capacity	918:948	a very high adsorption capacity of 485.87 mg g-1	918:965	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	4	59	contain	had	914:916	arg1	it					911:912	it	911:912	it	911:912	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	3	60	theme	%	835:835	arg1	%					802:802	1026.56%	795:802	1026.56%	795:802	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	3	60	theme	%	835:835	arg1	porosity					818:825	macropore porosity	808:825	macropore porosity	808:825	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	3	60	theme	%	835:835	arg1	%					835:835	62.29%	830:835	62.29%	830:835	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	3	61	theme	welling	778:784	arg1	ratio					786:790	a very high welling ratio	766:790	a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins	766:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	2	62	theme	liquid	710:715	arg1	membrane					718:725	the poly (ionic liquid) membrane	694:725	the poly (ionic liquid) membrane without calcium alginate	694:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	4	63	theme	BSA	1025:1027	arg1	concentration					1008:1020	the initial concentration	996:1020	the initial concentration of BSA	996:1027	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	6	64	theme	cryogel	1235:1241	arg1	membrane					1243:1250	the protein-imprinted cryogel membrane	1213:1250	the protein-imprinted cryogel membrane	1213:1250	This work can provide a potential method to prepare the protein-imprinted cryogel membrane with both high mechanical strength and imprinting efficiency.					
36364136	2	65	contain	had	472:474	arg2	strength					497:504	excellent mechanical strength	476:504	excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate	476:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	2	65	contain	had	472:474	arg1	MICM					467:470	the MICM	463:470	the MICM	463:470	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	5	66	theme	protein	1141:1147	arg1	separation					1149:1158	protein separation	1141:1158	protein separation	1141:1158	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	2	67	theme	ionic	704:708	arg1	membrane					718:725	the poly (ionic liquid) membrane	694:725	the poly (ionic liquid) membrane without calcium alginate	694:750	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36364136	3	68	theme	effective	856:864	arg1	transport					871:879	effective mass transport	856:879	effective mass transport of proteins	856:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	0	69	theme	Ionic	72:76	arg1	Membrane					121:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane	66:128	Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin.					
36364136	3	70	theme	mass	866:869	arg1	transport					871:879	effective mass transport	856:879	effective mass transport of proteins	856:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	4	71	theme	adsorption	930:939	arg1	capacity					941:948	a very high adsorption capacity	918:948	a very high adsorption capacity of 485.87 mg g-1	918:965	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	1	72	theme	mechanical	228:237	arg1	strength					239:246	the mechanical strength	224:246	the mechanical strength	224:246	In order to improve the mechanical strength and imprinting efficiency, a novel bovine serum albumin (BSA) molecularly imprinted poly(ionic liquid)/calcium alginate composite cryogel membrane (MICM) was prepared.					
36364136	4	73	theme	g-1	963:965	arg1	capacity					941:948	a very high adsorption capacity	918:948	a very high adsorption capacity of 485.87 mg g-1	918:965	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	4	74	theme	initial	1000:1006	arg1	concentration					1008:1020	the initial concentration	996:1020	the initial concentration of BSA	996:1027	More remarkably, it had a very high adsorption capacity of 485.87 mg g-1 at 20 °C and 0.66 mg mL-1 of the initial concentration of BSA.					
36364136	5	75	theme	selective	1059:1067	arg1	recognition					1085:1095	good selective and competitive recognition	1054:1095	good selective and competitive recognition	1054:1095	Moreover, MICM also had good selective and competitive recognition toward BSA, exhibiting potential utility in protein separation.					
36364136	3	76	theme	high	773:776	arg1	ratio					786:790	a very high welling ratio	766:790	a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins	766:891	The MICM had a very high welling ratio of 1026.56% and macropore porosity of 62.29%, which can provide effective mass transport of proteins.					
36364136	2	77	theme	mechanical	486:495	arg1	strength					497:504	excellent mechanical strength	476:504	excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate	476:621	The results of the tensile test indicated that the MICM had excellent mechanical strength which could reach up to 90.00 KPa, 30.30 times higher than the poly (ionic liquid) membrane without calcium alginate; the elongation of it could reach up to 93.70%, 8.28 times higher than the poly (ionic liquid) membrane without calcium alginate.					
36737205	7	0	theme	excellent	1208:1216	arg1	tolerance					1227:1235	excellent freezing tolerance	1208:1235	excellent freezing tolerance	1208:1235	Otherwise, LiCl increases the interactions between the colloidal phase and water molecules, endowing the hydrogels with excellent freezing tolerance.					
36737205	8	1	theme	movements	1484:1492	arg1	range					1469:1473	a wide range	1462:1473	a wide range of human movements and physiological activities	1462:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	5	2	theme	molecular	836:844	arg1	chains					846:851	the molecular chains	832:851	the molecular chains in the micro	832:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	3	3	theme	extreme	534:540	arg1	conditions					547:556	extreme cold conditions	534:556	extreme cold conditions	534:556	However, the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions is still challenging.					
36737205	1	4	theme	wearable	256:263	arg1	sensors					265:271	wearable sensors	256:271	wearable sensors	256:271	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	7	5	theme	freezing	1218:1225	arg1	tolerance					1227:1235	excellent freezing tolerance	1208:1235	excellent freezing tolerance	1208:1235	Otherwise, LiCl increases the interactions between the colloidal phase and water molecules, endowing the hydrogels with excellent freezing tolerance.					
36737205	8	6	theme	activities	1512:1521	arg1	range					1469:1473	a wide range	1462:1473	a wide range of human movements and physiological activities	1462:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	5	7	from	strength	897:904	arg1	macro					950:954	the macro	946:954	the macro	946:954	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	3	8	theme	cold	542:545	arg1	conditions					547:556	extreme cold conditions	534:556	extreme cold conditions	534:556	However, the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions is still challenging.					
36737205	1	9	theme	sensors	265:271	arg1	fabrication					241:251	fabrication	241:251	fabrication	241:251	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	1	9	theme	sensors	265:271	arg1	design					230:235	design	230:235	design	230:235	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	0	10	theme	strain	112:117	arg1	sensors					119:125	wearable strain sensors	103:125	wearable strain sensors	103:125	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	8	11	theme	physiological	1498:1510	arg1	activities					1512:1521	physiological activities	1498:1521	physiological activities	1498:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	8	12	theme	high	1413:1416	arg1	sensitivity					1418:1428	high sensitivity	1413:1428	high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities	1413:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	2	13	theme	flexible	295:302	arg1	hydrogels					315:323	these flexible conductive hydrogels	289:323	these flexible conductive hydrogels	289:323	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	4	14	theme	superior	634:641	arg1	conductivity					643:654	superior conductivity	634:654	superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT	634:701	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	0	15	theme	wearable	103:110	arg1	sensors					119:125	wearable strain sensors	103:125	wearable strain sensors	103:125	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	7	16	theme	colloidal	1143:1151	arg1	phase					1153:1157	the colloidal phase	1139:1157	the colloidal phase	1139:1157	Otherwise, LiCl increases the interactions between the colloidal phase and water molecules, endowing the hydrogels with excellent freezing tolerance.					
36737205	4	17	theme	cellulose	714:722	arg1	PAM/PEDOT					737:745	PAM/PEDOT	737:745	PAM/PEDOT:PSS/CNF	737:753	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	4	17	theme	cellulose	714:722	arg1	nanofibrils					724:734	PSS coated cellulose nanofibrils	703:734	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	8	18	theme	stable	1298:1303	arg1	properties					1316:1325	stable mechanical properties	1298:1325	stable mechanical properties	1298:1325	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	4	19	theme	coated	707:712	arg1	PAM/PEDOT					737:745	PAM/PEDOT	737:745	PAM/PEDOT:PSS/CNF	737:753	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	4	19	theme	coated	707:712	arg1	nanofibrils					724:734	PSS coated cellulose nanofibrils	703:734	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	5	20	theme	chains	846:851	arg1	sites					823:827	the hydrogen bonding sites	802:827	the hydrogen bonding sites of the molecular chains in the micro	802:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	20	theme	chains	846:851	arg1	chains					846:851	the molecular chains	832:851	the molecular chains in the micro	832:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	3	21	theme	hydrogel-based	493:506	arg1	sensors					508:514	high-performance hydrogel-based sensors	476:514	high-performance hydrogel-based sensors that can restrain extreme cold conditions	476:556	However, the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions is still challenging.					
36737205	6	22	theme	compressive	1016:1026	arg1	strength					1028:1035	compressive strength	1016:1035	compressive strength of 0.92 MPa	1016:1047	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	8	23	theme	optimized	1256:1264	arg1	hydrogel					1266:1273	the optimized hydrogel	1252:1273	the optimized hydrogel of 45 % LiCl	1252:1286	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	1	24	theme	high	183:186	arg1	sensitivity					188:198	high sensitivity	183:198	high sensitivity	183:198	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	5	25	theme	CNF	788:790	arg1	addition					776:783	The addition	772:783	The addition of CNF	772:790	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	26	theme	hydrogel	934:941	arg1	strength					897:904	the mechanical strength	882:904	the mechanical strength	882:904	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	26	theme	hydrogel	934:941	arg1	conductivity					914:925	the conductivity	910:925	the conductivity of the hydrogel in the macro	910:954	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	6	27	theme	41.9 kJ/m3	1076:1085	arg1	strength					1028:1035	compressive strength	1016:1035	compressive strength of 0.92 MPa	1016:1047	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	27	theme	41.9 kJ/m3	1076:1085	arg1	strength					994:1001	a high tensile strength	979:1001	a high tensile strength of 0.19 MPa	979:1013	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	27	theme	41.9 kJ/m3	1076:1085	arg1	energy					1066:1071	dissipation energy	1054:1071	dissipation energy of 41.9 kJ/m3	1054:1085	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	5	28	theme	bonding	815:821	arg1	sites					823:827	the hydrogen bonding sites	802:827	the hydrogen bonding sites of the molecular chains in the micro	802:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	28	theme	bonding	815:821	arg1	chains					846:851	the molecular chains	832:851	the molecular chains in the micro	832:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	29	from	sites	823:827	arg1	micro					860:864	the micro	856:864	the micro	856:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	1	30	with	Hydrogels	128:136	arg1	versatility					166:176	versatility	166:176	versatility	166:176	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	1	30	with	Hydrogels	128:136	arg1	flexibility					153:163	prominent flexibility	143:163	prominent flexibility	143:163	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	1	30	with	Hydrogels	128:136	arg1	sensitivity					188:198	high sensitivity	183:198	high sensitivity	183:198	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	2	31	theme	elastic	333:339	arg1	modulus					341:347	elastic modulus	333:347	elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing	333:445	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	6	32	theme	dissipation	1054:1064	arg1	energy					1066:1071	dissipation energy	1054:1071	dissipation energy of 41.9 kJ/m3	1054:1085	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	0	33	theme	Strong	0:5	arg1	polyacrylamide/PEDOT					42:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT	0:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils	0:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	4	34	dep	PAM/PEDOT	737:745	arg1	PSS/CNF					747:753	PSS/CNF	747:753	PAM/PEDOT:PSS/CNF	737:753	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	8	35	theme	mechanical	1305:1314	arg1	properties					1316:1325	stable mechanical properties	1298:1325	stable mechanical properties	1298:1325	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	5	36	from	conductivity	914:925	arg1	macro					950:954	the macro	946:954	the macro	946:954	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	3	37	theme	high-performance	476:491	arg1	sensors					508:514	high-performance hydrogel-based sensors	476:514	high-performance hydrogel-based sensors that can restrain extreme cold conditions	476:556	However, the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions is still challenging.					
36737205	0	38	theme	conductive	8:17	arg1	polyacrylamide/PEDOT					42:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT	0:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils	0:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	4	39	theme	anti-freezing	596:608	arg1	hydrogel					620:627	a novel anti-freezing composite hydrogel	588:627	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	8	40	theme	flexible	1391:1398	arg1	sensors					1400:1406	flexible sensors	1391:1406	flexible sensors	1391:1406	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	2	41	theme	conductive	304:313	arg1	hydrogels					315:323	these flexible conductive hydrogels	289:323	these flexible conductive hydrogels	289:323	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	2	42	theme	flexible	430:437	arg1	sensing					439:445	flexible sensing	430:445	flexible sensing	430:445	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	0	43	theme	freezing-tolerant	24:40	arg1	polyacrylamide/PEDOT					42:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT	0:61	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils	0:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	4	44	theme	novel	590:594	arg1	hydrogel					620:627	a novel anti-freezing composite hydrogel	588:627	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	8	45	theme	%	1281:1281	arg1	LiCl					1283:1286	45 % LiCl	1278:1286	45 % LiCl	1278:1286	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	2	46	theme	great	410:414	arg1	potential					416:424	the great potential	406:424	the great potential for flexible sensing	406:445	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	4	47	theme	composite	610:618	arg1	hydrogel					620:627	a novel anti-freezing composite hydrogel	588:627	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	4	48	dep	hydrogel	620:627	arg1	PAM/PEDOT					737:745	PAM/PEDOT	737:745	PAM/PEDOT:PSS/CNF	737:753	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	4	48	dep	hydrogel	620:627	arg1	nanofibrils					724:734	PSS coated cellulose nanofibrils	703:734	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	0	49	dep	polyacrylamide/PEDOT	42:61	arg1	nanofibrils					77:87	PSS/cellulose nanofibrils	63:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils	0:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	6	50	theme	0.92 MPa	1040:1047	arg1	strength					1028:1035	compressive strength	1016:1035	compressive strength of 0.92 MPa	1016:1047	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	50	theme	0.92 MPa	1040:1047	arg1	strength					994:1001	a high tensile strength	979:1001	a high tensile strength of 0.19 MPa	979:1013	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	50	theme	0.92 MPa	1040:1047	arg1	energy					1066:1071	dissipation energy	1054:1071	dissipation energy of 41.9 kJ/m3	1054:1085	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	8	51	used	used	1374:1377	arg2	hydrogel					1361:1368	the composite hydrogel	1347:1368	the composite hydrogel	1347:1368	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	7	52	with	hydrogels	1193:1201	arg1	tolerance					1227:1235	excellent freezing tolerance	1208:1235	excellent freezing tolerance	1208:1235	Otherwise, LiCl increases the interactions between the colloidal phase and water molecules, endowing the hydrogels with excellent freezing tolerance.					
36737205	5	53	theme	hydrogen	806:813	arg1	bonding					815:821	hydrogen bonding	806:821	the hydrogen bonding sites of the molecular chains in the micro	802:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	8	54	theme	wide	1464:1467	arg1	range					1469:1473	a wide range	1462:1473	a wide range of human movements and physiological activities	1462:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	8	55	theme	LiCl	1283:1286	arg1	hydrogel					1266:1273	the optimized hydrogel	1252:1273	the optimized hydrogel of 45 % LiCl	1252:1286	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	8	56	theme	10.3 MPa-1	1433:1442	arg1	sensitivity					1418:1428	high sensitivity	1413:1428	high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities	1413:1521	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	2	57	with	compatible	364:373	arg1	skin					386:389	human skin	380:389	human skin	380:389	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36737205	5	58	from	chains	846:851	arg1	micro					860:864	the micro	856:864	the micro	856:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	1	59	theme	prominent	143:151	arg1	flexibility					153:163	prominent flexibility	143:163	prominent flexibility	143:163	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	5	60	from	macro	950:954	arg1	strength					897:904	the mechanical strength	882:904	the mechanical strength	882:904	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	60	from	macro	950:954	arg1	conductivity					914:925	the conductivity	910:925	the conductivity of the hydrogel in the macro	910:954	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	6	61	theme	high	981:984	arg1	strength					994:1001	a high tensile strength	979:1001	a high tensile strength of 0.19 MPa	979:1013	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	8	62	theme	composite	1351:1359	arg1	hydrogel					1361:1368	the composite hydrogel	1347:1368	the composite hydrogel	1347:1368	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	8	63	theme	human	1478:1482	arg1	movements					1484:1492	human movements	1478:1492	human movements	1478:1492	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	5	64	theme	mechanical	886:895	arg1	strength					897:904	the mechanical strength	882:904	the mechanical strength	882:904	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	65	from	hydrogel	934:941	arg1	macro					950:954	the macro	946:954	the macro	946:954	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	3	66	theme	sensors	508:514	arg1	preparation					461:471	the preparation	457:471	the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions	457:556	However, the preparation of high-performance hydrogel-based sensors that can restrain extreme cold conditions is still challenging.					
36737205	8	67	theme	45 	1278:1280	arg1	%					1281:1281	%	1281:1281	%	1281:1281	Specifically, the optimized hydrogel of 45 % LiCl exhibited stable mechanical properties at -40 °C. Finally, the composite hydrogel was used to assemble flexible sensors with high sensitivity of 10.3 MPa-1, which can detect a wide range of human movements and physiological activities.					
36737205	4	68	with	hydrogel	620:627	arg1	conductivity					643:654	superior conductivity	634:654	superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT	634:701	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	1	69	theme	important	208:216	arg1	role					218:221	an important role	205:221	an important role	205:221	Hydrogels with prominent flexibility, versatility, and high sensitivity play an important role in the design and fabrication of wearable sensors.					
36737205	4	70	theme	PSS	703:705	arg1	PAM/PEDOT					737:745	PAM/PEDOT	737:745	PAM/PEDOT:PSS/CNF	737:753	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	4	70	theme	PSS	703:705	arg1	nanofibrils					724:734	PSS coated cellulose nanofibrils	703:734	a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF)	588:754	Herein, a novel anti-freezing composite hydrogel with superior conductivity based on polyacrylamide (PAM), LiCl, and PEDOT:PSS coated cellulose nanofibrils (PAM/PEDOT:PSS/CNF) is constructed.					
36737205	6	71	theme	tensile	986:992	arg1	strength					994:1001	a high tensile strength	979:1001	a high tensile strength of 0.19 MPa	979:1013	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	72	theme	0.19 MPa	1006:1013	arg1	strength					1028:1035	compressive strength	1016:1035	compressive strength of 0.92 MPa	1016:1047	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	72	theme	0.19 MPa	1006:1013	arg1	strength					994:1001	a high tensile strength	979:1001	a high tensile strength of 0.19 MPa	979:1013	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	6	72	theme	0.19 MPa	1006:1013	arg1	energy					1066:1071	dissipation energy	1054:1071	dissipation energy of 41.9 kJ/m3	1054:1085	The hydrogels achieve a high tensile strength of 0.19 MPa, compressive strength of 0.92 MPa, and dissipation energy of 41.9 kJ/m3.					
36737205	0	73	theme	PSS/cellulose	63:75	arg1	nanofibrils					77:87	PSS/cellulose nanofibrils	63:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils	0:87	Strong, conductive, and freezing-tolerant polyacrylamide/PEDOT:PSS/cellulose nanofibrils hydrogels for wearable strain sensors.					
36737205	7	74	theme	water	1163:1167	arg1	molecules					1169:1177	water molecules	1163:1177	water molecules	1163:1177	Otherwise, LiCl increases the interactions between the colloidal phase and water molecules, endowing the hydrogels with excellent freezing tolerance.					
36737205	5	75	from	micro	860:864	arg1	sites					823:827	the hydrogen bonding sites	802:827	the hydrogen bonding sites of the molecular chains in the micro	802:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	5	75	from	micro	860:864	arg1	chains					846:851	the molecular chains	832:851	the molecular chains in the micro	832:864	The addition of CNF increased the hydrogen bonding sites of the molecular chains in the micro, thus improving the mechanical strength and the conductivity of the hydrogel in the macro.					
36737205	2	76	theme	human	380:384	arg1	skin					386:389	human skin	380:389	human skin	380:389	In particular, these flexible conductive hydrogels exhibit elastic modulus that is highly compatible with human skin, demonstrating the great potential for flexible sensing.					
36122434	1	0	theme	sponge	245:250	arg1	composite					252:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
36122434	5	1	dep	precision	840:848	arg1	precision					861:869	intra-day precision	851:869	intra-day precision	851:869	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	1	dep	precision	840:848	arg1	precision					893:901	inter-day precision	883:901	inter-day precision	883:901	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	2	dep	limit	793:797	arg1	8.250-16.33 ng L-1					813:830	8.250-16.33 ng L-1	813:830	limit of detection: 8.250-16.33 ng L-1	793:830	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	3	3	from	analysis	484:491	arg1	samples					527:533	water samples	521:533	water samples	521:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	2	4	theme	syringe	342:348	arg1	barrel					350:355	the syringe barrel	338:355	the syringe barrel	338:355	The composite was packed in the syringe barrel and used as the sorbent for microextraction in packed syringe.					
36122434	3	5	from	samples	527:533	arg1	analysis					484:491	the analysis	480:491	the analysis of trace nitroimidazoles in water samples	480:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	4	6	theme	extraction	565:574	arg1	efficiency					576:585	the extraction efficiency	561:585	the extraction efficiency	561:585	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	0	7	theme	packed	99:104	arg1	syringe					106:112	packed syringe	99:112	packed syringe	99:112	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	5	8	dep	sensitivity	780:790	arg1	limit					793:797	limit	793:797	limit of detection: 8.250-16.33 ng L-1	793:830	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	9	dep	%	907:907	arg1	%					912:912	-6.7%	908:912	1.8%-6.7%	904:912	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	10	theme	detection	802:810	arg1	limit					793:797	limit	793:797	limit of detection: 8.250-16.33 ng L-1	793:830	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	2	11	used	used	361:364	arg2	composite					314:322	The composite	310:322	The composite	310:322	The composite was packed in the syringe barrel and used as the sorbent for microextraction in packed syringe.					
36122434	2	11	used	used	361:364	arg2	sorbent					373:379	the sorbent	369:379	the sorbent for microextraction in packed syringe	369:417	The composite was packed in the syringe barrel and used as the sorbent for microextraction in packed syringe.					
36122434	4	12	theme	sample	641:646	arg1	volume					657:662	sample solution volume	641:662	sample solution volume	641:662	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	5	13	theme	good	730:733	arg1	linearity					735:743	good linearity	730:743	good linearity (r > 0.99 for five analytes)	730:772	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	3	14	theme	water	521:525	arg1	samples					527:533	water samples	521:533	water samples	521:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	5	15	theme	high	775:778	arg1	sensitivity					780:790	high sensitivity	775:790	high sensitivity (limit of detection: 8.250-16.33 ng L-1)	775:831	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	16	dep	precision	861:869	arg1	%					875:875	1.1%	872:875	1.1%-5.3%	872:880	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	16	dep	precision	861:869	arg1	%					907:907	1.8%	904:907	1.8%-6.7%	904:912	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	17	theme	ideal	834:838	arg1	precision					840:848	ideal precision	834:848	ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%)	834:913	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	18	dep	linearity	735:743	arg1	r > 0.99					746:753	r > 0.99	746:753	r > 0.99 for five analytes	746:771	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	19	theme	inter-day	883:891	arg1	precision					893:901	inter-day precision	883:901	inter-day precision	883:901	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	19	theme	inter-day	883:891	arg1	precision					861:869	intra-day precision	851:869	intra-day precision	851:869	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	4	20	theme	solution	648:655	arg1	volume					657:662	sample solution volume	641:662	sample solution volume	641:662	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	3	21	from	nitroimidazoles	502:516	arg1	samples					527:533	water samples	521:533	water samples	521:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	3	22	theme	proposed	447:454	arg1	method					456:461	the proposed method	443:461	the proposed method	443:461	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	0	23	theme	compressible	15:26	arg1	Cr					36:37	Cr	36:37	Cr	36:37	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	0	23	theme	compressible	15:26	arg1	MIL-101					28:34	compressible MIL-101	15:34	compressible MIL-101(Cr)	15:38	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	1	24	theme	simple	287:292	arg1	method					302:307	a simple soaking method	285:307	a simple soaking method	285:307	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
36122434	0	25	theme	trace	122:126	arg1	nitroimidazoles					128:142	trace nitroimidazoles	122:142	trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis	122:188	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	0	26	from	microextraction	80:94	arg1	syringe					106:112	packed syringe	99:112	packed syringe	99:112	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	6	27	theme	proposed	984:991	arg1	efficient					1017:1025	efficient	1017:1025	efficient	1017:1025	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	6	27	theme	proposed	984:991	arg1	method					993:998	The proposed method	980:998	The proposed method	980:998	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	6	27	theme	proposed	984:991	arg1	operative					1035:1043	operative	1035:1043	operative	1035:1043	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	2	28	theme	packed	404:409	arg1	syringe					411:417	packed syringe	404:417	packed syringe	404:417	The composite was packed in the syringe barrel and used as the sorbent for microextraction in packed syringe.					
36122434	1	29	theme	soaking	294:300	arg1	method					302:307	a simple soaking method	285:307	a simple soaking method	285:307	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
36122434	0	30	theme	water	147:151	arg1	samples					153:159	water samples	147:159	water samples prior to UPLC-MS/MS analysis	147:188	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	4	31	theme	solution	631:638	arg1	solvent					676:682	elution solvent	668:682	elution solvent	668:682	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	4	31	theme	solution	631:638	arg1	parameters					540:549	The parameters	536:549	The parameters affecting the extraction efficiency	536:585	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	4	31	theme	solution	631:638	arg1	value					615:619	pH value	612:619	pH value of sample solution	612:638	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	4	31	theme	solution	631:638	arg1	volume					657:662	sample solution volume	641:662	sample solution volume	641:662	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	4	31	theme	solution	631:638	arg1	type					606:609	sorbent type	598:609	sorbent type	598:609	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	5	32	dep	recovery	942:949	arg1	%					962:962	70.4%-96.7%	952:962	70.4%-96.7%	952:962	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	1	33	theme	MIL-101	206:212	arg1	composite					252:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
36122434	4	34	theme	elution	668:674	arg1	solvent					676:682	elution solvent	668:682	elution solvent	668:682	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	0	35	from	nitroimidazoles	128:142	arg1	samples					153:159	water samples	147:159	water samples prior to UPLC-MS/MS analysis	147:188	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	4	36	theme	sample	624:629	arg1	solution					631:638	sample solution	624:638	sample solution	624:638	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	0	37	theme	/cellulose	39:48	arg1	sponge					67:72	/cellulose aerogel/melamine sponge	39:72	/cellulose aerogel/melamine sponge	39:72	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	5	38	theme	optimal	710:716	arg1	conditions					718:727	the optimal conditions	706:727	the optimal conditions	706:727	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	39	theme	%	956:956	arg1	%					962:962	70.4%-96.7%	952:962	70.4%-96.7%	952:962	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	6	40	dep	efficient	1017:1025	arg1	efficient					1017:1025	efficient	1017:1025	efficient	1017:1025	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	6	40	dep	efficient	1017:1025	arg1	operative					1035:1043	operative	1035:1043	operative	1035:1043	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	6	40	dep	efficient	1017:1025	arg1	method					993:998	The proposed method	980:998	The proposed method	980:998	The proposed method was proved to be efficient, easily operative and environmentally friendly.					
36122434	0	41	theme	UPLC-MS/MS	170:179	arg1	analysis					181:188	UPLC-MS/MS analysis	170:188	UPLC-MS/MS analysis	170:188	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	2	42	from	sorbent	373:379	arg1	syringe					411:417	packed syringe	404:417	packed syringe	404:417	The composite was packed in the syringe barrel and used as the sorbent for microextraction in packed syringe.					
36122434	5	43	dep	%	875:875	arg1	%					880:880	-5.3%	876:880	1.1%-5.3%	872:880	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	44	theme	intra-day	851:859	arg1	precision					861:869	intra-day precision	851:869	intra-day precision	851:869	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	44	theme	intra-day	851:859	arg1	precision					893:901	inter-day precision	883:901	inter-day precision	883:901	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	4	45	theme	sorbent	598:604	arg1	type					606:609	sorbent type	598:609	sorbent type	598:609	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	5	46	theme	satisfactory	919:930	arg1	recovery					942:949	recovery	942:949	recovery	942:949	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	5	46	theme	satisfactory	919:930	arg1	accuracy					932:939	satisfactory accuracy	919:939	satisfactory accuracy (recovery: 70.4%-96.7%)	919:963	Under the optimal conditions, good linearity (r > 0.99 for five analytes), high sensitivity (limit of detection: 8.250-16.33 ng L-1), ideal precision (intra-day precision: 1.1%-5.3%, inter-day precision: 1.8%-6.7%) and satisfactory accuracy (recovery: 70.4%-96.7%) were achieved.					
36122434	4	47	theme	pH	612:613	arg1	value					615:619	pH value	612:619	pH value of sample solution	612:638	The parameters affecting the extraction efficiency, including sorbent type, pH value of sample solution, sample solution volume and elution solvent were optimized.					
36122434	3	48	theme	trace	496:500	arg1	nitroimidazoles					502:516	trace nitroimidazoles	496:516	trace nitroimidazoles in water samples	496:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	1	49	theme	/cellulose	217:226	arg1	composite					252:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
36122434	0	50	theme	aerogel/melamine	50:65	arg1	sponge					67:72	/cellulose aerogel/melamine sponge	39:72	/cellulose aerogel/melamine sponge	39:72	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	0	51	dep	Monolithic	0:9	arg1	sponge					67:72	/cellulose aerogel/melamine sponge	39:72	/cellulose aerogel/melamine sponge	39:72	Monolithic and compressible MIL-101(Cr)/cellulose aerogel/melamine sponge based microextraction in packed syringe towards trace nitroimidazoles in water samples prior to UPLC-MS/MS analysis.					
36122434	3	52	theme	nitroimidazoles	502:516	arg1	analysis					484:491	the analysis	480:491	the analysis of trace nitroimidazoles in water samples	480:533	Coupled to UPLC-MS/MS, the proposed method was employed for the analysis of trace nitroimidazoles in water samples.					
36122434	1	53	theme	aerogel/melamine	228:243	arg1	composite					252:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	MIL-101(Cr)/cellulose aerogel/melamine sponge composite	206:260	In this study, MIL-101(Cr)/cellulose aerogel/melamine sponge composite was fabricated through a simple soaking method.					
35509210	2	0	theme	xylem	107:111	arg1	Colonization					87:98	Colonization	87:98	Colonization of the xylem of sugarcane by Leifsonia xyli subsp.	87:149	Colonization of the xylem of sugarcane by Leifsonia xyli subsp.					
35509210	9	1	theme	bacterial	1049:1057	arg1	populations					1059:1069	higher bacterial populations	1042:1069	higher bacterial populations	1042:1069	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	5	2	dep	revealed	534:541	arg1	subsp					570:574	L. xyli subsp	562:574	L. xyli subsp	562:574	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	0	3	theme	xyli	69:72	arg1	subsp					74:78	Leifsonia xyli subsp	59:78	Leifsonia xyli subsp	59:78	Histopathology of the Shoot Apex of Sugarcane Colonized by Leifsonia xyli subsp.					
35509210	7	4	with	plants	778:783	arg1	titers					797:802	higher titers	790:802	higher titers	790:802	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	8	5	theme	pectin	942:947	arg1	composition					905:915	The mixed composition	895:915	The mixed composition of lipids, proteins, and pectin	895:947	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	10	6	theme	fewer	1302:1306	arg1	cells					1308:1312	fewer cells	1302:1312	fewer cells	1302:1312	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	8	7	theme	lipids	920:925	arg1	composition					905:915	The mixed composition	895:915	The mixed composition of lipids, proteins, and pectin	895:947	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	9	8	theme	reported	1182:1189	arg1	downregulation					1191:1204	the reported downregulation	1178:1204	the reported downregulation of photosynthesis	1178:1222	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	10	9	theme	genes	1340:1344	arg1	expression					1326:1335	expression	1326:1335	expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue	1326:1419	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	7	10	theme	granular	847:854	arg1	material					856:863	a granular material	845:863	a granular material filling the vessels observed	845:892	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	7	11	theme	secondary	749:757	arg1	walls					759:763	the secondary walls	745:763	the secondary walls	745:763	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	2	12	theme	xyli	139:142	arg1	subsp					144:148	Leifsonia xyli subsp	129:148	Leifsonia xyli subsp	129:148	Colonization of the xylem of sugarcane by Leifsonia xyli subsp.					
35509210	3	13	theme	vessels	188:194	arg1	occlusion					171:179	the occlusion	167:179	the occlusion of the vessels by a gum-like compound	167:217	xyli results in the occlusion of the vessels by a gum-like compound and compromises the elongation of the stalk leading to stunted plants.					
35509210	7	14	theme	walls	835:839	arg1	material					856:863	a granular material	845:863	a granular material filling the vessels observed	845:892	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	7	14	theme	walls	835:839	arg1	degradation					816:826	a mild degradation	809:826	a mild degradation of the walls	809:839	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	5	15	theme	Microscopic	427:437	arg1	analyses					457:464	Microscopic and histochemical analyses	427:464	Microscopic and histochemical analyses	427:464	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	2	16	theme	Leifsonia	129:137	arg1	subsp					144:148	Leifsonia xyli subsp	129:148	Leifsonia xyli subsp	129:148	Colonization of the xylem of sugarcane by Leifsonia xyli subsp.					
35509210	5	17	theme	L.	562:563	arg1	subsp					570:574	L. xyli subsp	562:574	L. xyli subsp	562:574	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	9	18	theme	lower	1086:1090	arg1	content					1099:1105	lower starch content	1086:1105	lower starch content in the ground parenchyma	1086:1130	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	10	19	theme	related	1346:1352	arg1	genes					1340:1344	genes	1340:1344	genes related to the cell cycle and to the synthesis of ABA in the apical tissue	1340:1419	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	6	20	theme	xylem	634:638	arg1	vessels					640:646	the forming xylem vessels	622:646	the forming xylem vessels	622:646	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	10	21	theme	cell	1361:1364	arg1	cycle					1366:1370	the cell cycle	1357:1370	the cell cycle	1357:1370	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	9	22	theme	photosynthesis	1209:1222	arg1	accumulation					1238:1249	increased accumulation	1228:1249	increased accumulation of phenolics	1228:1262	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	9	22	theme	photosynthesis	1209:1222	arg1	downregulation					1191:1204	the reported downregulation	1178:1204	the reported downregulation of photosynthesis	1178:1222	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	5	23	theme	xyli	565:568	arg1	subsp					570:574	L. xyli subsp	562:574	L. xyli subsp	562:574	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	5	24	theme	bacterial	513:521	arg1	titers					523:528	lower and higher bacterial titers	496:528	lower and higher bacterial titers	496:528	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	5	25	theme	histochemical	443:455	arg1	analyses					457:464	Microscopic and histochemical analyses	427:464	Microscopic and histochemical analyses	427:464	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	2	26	theme	sugarcane	116:124	arg1	xylem					107:111	the xylem	103:111	the xylem of sugarcane	103:124	Colonization of the xylem of sugarcane by Leifsonia xyli subsp.					
35509210	3	27	theme	gum-like	201:208	arg1	compound					210:217	a gum-like compound	199:217	a gum-like compound	199:217	xyli results in the occlusion of the vessels by a gum-like compound and compromises the elongation of the stalk leading to stunted plants.					
35509210	8	28	theme	polymeric	1009:1017	arg1	substance					1019:1027	a bacterial extracellular polymeric substance	983:1027	a bacterial extracellular polymeric substance	983:1027	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	8	28	theme	polymeric	1009:1017	arg1	filling					968:974	the filling	964:974	the filling	964:974	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	6	29	from	tissue	601:606	arg1	present					585:591	present	585:591	present	585:591	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	9	30	theme	increased	1228:1236	arg1	accumulation					1238:1249	increased accumulation	1228:1249	increased accumulation of phenolics	1228:1262	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	6	31	theme	forming	626:632	arg1	vessels					640:646	the forming xylem vessels	622:646	the forming xylem vessels	622:646	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	4	32	theme	apical	334:339	arg1	tissue					341:346	the apical tissue	330:346	the apical tissue where the elongation of the stalks initiates at the intercalary meristem (IM)	330:424	However, no study has been performed in the apical tissue where the elongation of the stalks initiates at the intercalary meristem (IM).					
35509210	11	33	theme	L.	1460:1461	arg1	subsp					1468:1472	L. xyli subsp	1460:1472	L. xyli subsp	1460:1472	These results indicate that increased L. xyli subsp.					
35509210	8	34	theme	mixed	899:903	arg1	composition					905:915	The mixed composition	895:915	The mixed composition of lipids, proteins, and pectin	895:947	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	0	35	theme	Shoot	22:26	arg1	Apex					28:31	the Shoot Apex	18:31	the Shoot Apex of Sugarcane	18:44	Histopathology of the Shoot Apex of Sugarcane Colonized by Leifsonia xyli subsp.					
35509210	7	36	theme	mild	811:814	arg1	degradation					816:826	a mild degradation	809:826	a mild degradation of the walls	809:839	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	10	37	theme	third	1282:1286	arg1	IMs					1288:1290	Their second and third IMs	1265:1290	Their second and third IMs	1265:1290	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	12	38	theme	disease	1625:1631	arg1	symptom					1610:1616	the main symptom	1601:1616	the main symptom of the disease	1601:1631	xyli colonization affects the development of the IM, which ultimately would reduce the length of the internodes, resulting in the main symptom of the disease.					
35509210	10	39	theme	second	1271:1276	arg1	IMs					1288:1290	Their second and third IMs	1265:1290	Their second and third IMs	1265:1290	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	10	40	theme	apical	1407:1412	arg1	tissue					1414:1419	the apical tissue	1403:1419	the apical tissue	1403:1419	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	9	41	theme	ground	1114:1119	arg1	parenchyma					1121:1130	the ground parenchyma	1110:1130	the ground parenchyma	1110:1130	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	12	42	theme	main	1605:1608	arg1	symptom					1610:1616	the main symptom	1601:1616	the main symptom of the disease	1601:1631	xyli colonization affects the development of the IM, which ultimately would reduce the length of the internodes, resulting in the main symptom of the disease.					
35509210	5	43	dep	subsp	570:574	arg1	cases					556:560	both cases	551:560	both cases	551:560	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	9	44	theme	phenolics	1254:1262	arg1	accumulation					1238:1249	increased accumulation	1228:1249	increased accumulation of phenolics	1228:1262	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	9	44	theme	phenolics	1254:1262	arg1	downregulation					1191:1204	the reported downregulation	1178:1204	the reported downregulation of photosynthesis	1178:1222	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	12	45	theme	IM	1524:1525	arg1	development					1505:1515	the development	1501:1515	the development of the IM, which ultimately would reduce the length of the internodes	1501:1585	xyli colonization affects the development of the IM, which ultimately would reduce the length of the internodes, resulting in the main symptom of the disease.					
35509210	6	46	located	present	585:591	arg1	tissue					601:606	this tissue	596:606	this tissue	596:606	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	6	46	located	present	585:591	arg2	xyli					577:580	xyli	577:580	xyli	577:580	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	0	47	theme	Apex	28:31	arg1	Histopathology					0:13	Histopathology	0:13	Histopathology of the Shoot Apex of Sugarcane	0:44	Histopathology of the Shoot Apex of Sugarcane Colonized by Leifsonia xyli subsp.					
35509210	7	48	located	observed	724:731	arg2	it					717:718	it	717:718	it	717:718	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	7	48	located	observed	724:731	arg1	cases					710:714	both cases	705:714	both cases	705:714	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	6	49	theme	developed	680:688	arg1	internodes					690:699	developed internodes	680:699	developed internodes	680:699	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	6	50	attach	present	585:591	arg2	xyli					577:580	xyli	577:580	xyli	577:580	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	6	50	attach	present	585:591	arg1	tissue					601:606	this tissue	596:606	this tissue	596:606	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	4	51	theme	intercalary	400:410	arg1	IM					422:423	IM	422:423	IM	422:423	However, no study has been performed in the apical tissue where the elongation of the stalks initiates at the intercalary meristem (IM).					
35509210	4	51	theme	intercalary	400:410	arg1	meristem					412:419	the intercalary meristem	396:419	the intercalary meristem (IM)	396:424	However, no study has been performed in the apical tissue where the elongation of the stalks initiates at the intercalary meristem (IM).					
35509210	5	52	theme	lower	496:500	arg1	titers					523:528	lower and higher bacterial titers	496:528	lower and higher bacterial titers	496:528	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	0	53	theme	Sugarcane	36:44	arg1	Apex					28:31	the Shoot Apex	18:31	the Shoot Apex of Sugarcane	18:44	Histopathology of the Shoot Apex of Sugarcane Colonized by Leifsonia xyli subsp.					
35509210	12	54	theme	xyli	1475:1478	arg1	colonization					1480:1491	xyli colonization	1475:1491	xyli colonization	1475:1491	xyli colonization affects the development of the IM, which ultimately would reduce the length of the internodes, resulting in the main symptom of the disease.					
35509210	3	55	theme	stunted	274:280	arg1	plants					282:287	stunted plants	274:287	stunted plants	274:287	xyli results in the occlusion of the vessels by a gum-like compound and compromises the elongation of the stalk leading to stunted plants.					
35509210	9	56	theme	node	1139:1142	arg1	elements					1144:1151	the node elements	1135:1151	the node elements	1135:1151	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	6	57	from	present	585:591	arg1	tissue					601:606	this tissue	596:606	this tissue	596:606	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	11	58	theme	xyli	1463:1466	arg1	subsp					1468:1472	L. xyli subsp	1460:1472	L. xyli subsp	1460:1472	These results indicate that increased L. xyli subsp.					
35509210	8	59	theme	proteins	928:935	arg1	composition					905:915	The mixed composition	895:915	The mixed composition of lipids, proteins, and pectin	895:947	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	3	60	theme	stalk	257:261	arg1	elongation					239:248	the elongation	235:248	the elongation of the stalk leading to stunted plants	235:287	xyli results in the occlusion of the vessels by a gum-like compound and compromises the elongation of the stalk leading to stunted plants.					
35509210	9	61	theme	starch	1092:1097	arg1	content					1099:1105	lower starch content	1086:1105	lower starch content in the ground parenchyma	1086:1130	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	8	62	theme	bacterial	985:993	arg1	substance					1019:1027	a bacterial extracellular polymeric substance	983:1027	a bacterial extracellular polymeric substance	983:1027	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	8	62	theme	bacterial	985:993	arg1	filling					968:974	the filling	964:974	the filling	964:974	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	5	63	theme	higher	506:511	arg1	titers					523:528	lower and higher bacterial titers	496:528	lower and higher bacterial titers	496:528	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	12	64	theme	internodes	1576:1585	arg1	length					1562:1567	the length	1558:1567	the length of the internodes	1558:1585	xyli colonization affects the development of the IM, which ultimately would reduce the length of the internodes, resulting in the main symptom of the disease.					
35509210	10	65	theme	ABA	1396:1398	arg1	synthesis					1383:1391	the synthesis	1379:1391	the synthesis of ABA in the apical tissue	1379:1419	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	7	66	dep	observed	724:731	arg1	material					856:863	a granular material	845:863	a granular material filling the vessels observed	845:892	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	7	66	dep	observed	724:731	arg1	degradation					816:826	a mild degradation	809:826	a mild degradation of the walls	809:839	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	9	67	from	content	1099:1105	arg1	parenchyma					1121:1130	the ground parenchyma	1110:1130	the ground parenchyma	1110:1130	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	7	68	theme	higher	790:795	arg1	titers					797:802	higher titers	790:802	higher titers	790:802	In both cases, it was observed adhering to the secondary walls, but only in plants with higher titers were a mild degradation of the walls and a granular material filling the vessels observed.					
35509210	5	69	with	plants	484:489	arg1	titers					523:528	lower and higher bacterial titers	496:528	lower and higher bacterial titers	496:528	Microscopic and histochemical analyses were performed in plants with lower and higher bacterial titers and revealed that in both cases L. xyli subsp.					
35509210	0	70	theme	Leifsonia	59:67	arg1	subsp					74:78	Leifsonia xyli subsp	59:78	Leifsonia xyli subsp	59:78	Histopathology of the Shoot Apex of Sugarcane Colonized by Leifsonia xyli subsp.					
35509210	4	71	theme	stalks	376:381	arg1	elongation					358:367	the elongation	354:367	the elongation of the stalks	354:381	However, no study has been performed in the apical tissue where the elongation of the stalks initiates at the intercalary meristem (IM).					
35509210	6	72	theme	similar	653:659	arg1	way					661:663	a similar way	651:663	a similar way	651:663	xyli is present in this tissue and colonizes the forming xylem vessels in a similar way as observed in developed internodes.					
35509210	9	73	with	Plants	1030:1035	arg1	populations					1059:1069	higher bacterial populations	1042:1069	higher bacterial populations	1042:1069	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	8	74	theme	extracellular	995:1007	arg1	substance					1019:1027	a bacterial extracellular polymeric substance	983:1027	a bacterial extracellular polymeric substance	983:1027	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	8	74	theme	extracellular	995:1007	arg1	filling					968:974	the filling	964:974	the filling	964:974	The mixed composition of lipids, proteins, and pectin indicates that the filling is not a bacterial extracellular polymeric substance.					
35509210	10	75	from	synthesis	1383:1391	arg1	tissue					1414:1419	the apical tissue	1403:1419	the apical tissue	1403:1419	Their second and third IMs presented fewer cells and reduced expression of genes related to the cell cycle and to the synthesis of ABA in the apical tissue.					
35509210	9	76	theme	higher	1042:1047	arg1	populations					1059:1069	higher bacterial populations	1042:1069	higher bacterial populations	1042:1069	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	9	77	attach	presented	1076:1084	arg1	elements					1144:1151	the node elements	1135:1151	the node elements	1135:1151	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
35509210	9	77	attach	presented	1076:1084	arg2	Plants					1030:1035	Plants	1030:1035	Plants with higher bacterial populations	1030:1069	Plants with higher bacterial populations also presented lower starch content in the ground parenchyma at the node elements, possibly resulting from the reported downregulation of photosynthesis and increased accumulation of phenolics.					
37356720	4	0	theme	A549	1009:1012	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	0	theme	A549	1009:1012	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	1	1	theme	phosphorylation	361:375	arg1	result					351:356	the result	347:356	the result of phosphorylation or citrullination	347:393	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	7	2	dep	substrate	1912:1920	arg1	properties					1959:1968	the glycocalyx adhesive properties	1935:1968	the glycocalyx adhesive properties	1935:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	6	3	theme	hyaluronic	1342:1351	arg1	GlcNAc					1448:1453	GlcNAc	1448:1453	GlcNAc	1448:1453	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	3	theme	hyaluronic	1342:1351	arg1	HA					1359:1360	HA	1359:1360	HA	1359:1360	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	3	theme	hyaluronic	1342:1351	arg1	treatments					1457:1466	treatments	1457:1466	treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels	1457:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	3	theme	hyaluronic	1342:1351	arg1	acid					1353:1356	hyaluronic acid	1342:1356	hyaluronic acid	1342:1356	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	1	4	theme	intermediate	167:178	arg1	filaments					180:188	Vimentin intermediate filaments	158:188	Vimentin intermediate filaments	158:188	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	6	5	contain	have	1473:1476	arg1	treatments					1457:1466	treatments	1457:1466	treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels	1457:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	5	contain	have	1473:1476	arg2	effect					1491:1496	no effect	1488:1496	no effect on the same cell types binding to collagen-coated hydrogels	1488:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	5	contain	have	1473:1476	arg2	little					1478:1483	little	1478:1483	little	1478:1483	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	5	contain	have	1473:1476	arg1	acid					1353:1356	hyaluronic acid	1342:1356	hyaluronic acid	1342:1356	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	6	from	spreading	1288:1296	arg1	surfaces					1317:1324	vimentin-coated surfaces	1301:1324	vimentin-coated surfaces	1301:1324	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	7	theme	soluble	1406:1412	arg1	heparin					1414:1420	soluble heparin	1406:1420	soluble heparin	1406:1420	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	5	8	theme	spheroid	1162:1169	arg1	assays					1181:1186	spheroid expansion assays	1162:1186	spheroid expansion assays	1162:1186	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	4	9	attach	linked	1106:1111	arg2	substrates					1084:1093	polyacrylamide hydrogel substrates	1060:1093	polyacrylamide hydrogel substrates covalently linked to vimentin	1060:1123	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	9	attach	linked	1106:1111	arg1	vimentin					1116:1123	vimentin	1116:1123	vimentin	1116:1123	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	7	10	theme	surface	1740:1746	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	2	11	theme	matrix	566:571	arg1	surfaces					526:533	surfaces	526:533	surfaces of cells and the extracellular matrix	526:571	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	1	12	theme	citrullination	380:393	arg1	result					351:356	the result	347:356	the result of phosphorylation or citrullination	347:393	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	7	13	contain	contain	1762:1768	arg2	glucosamine					1779:1789	N-acetyl glucosamine	1770:1789	N-acetyl glucosamine	1770:1789	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	13	contain	contain	1762:1768	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	13	contain	contain	1762:1768	arg1	glycocalyx					1707:1716	glycocalyx	1707:1716	glycocalyx	1707:1716	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	14	theme	extracellular	1837:1849	arg1	vimentin					1851:1858	extracellular vimentin	1837:1858	extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties	1837:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	4	15	theme	hydrogel	1075:1082	arg1	substrates					1084:1093	polyacrylamide hydrogel substrates	1060:1093	polyacrylamide hydrogel substrates covalently linked to vimentin	1060:1123	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	3	16	theme	adhesive	854:861	arg1	anchor					863:868	an adhesive anchor	851:868	an adhesive anchor for cells	851:878	The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized.					
37356720	3	16	theme	adhesive	854:861	arg1	vimentin					825:832	vimentin	825:832	vimentin alone	825:838	The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized.					
37356720	2	17	theme	extracellular	552:564	arg1	matrix					566:571	the extracellular matrix	548:571	the extracellular matrix	548:571	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	3	18	theme	extracellular	760:772	arg1	vimentin					774:781	extracellular vimentin	760:781	extracellular vimentin	760:781	The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized.					
37356720	7	19	theme	adhesion	1814:1821	arg1	receptors					1823:1831	adhesion receptors	1814:1831	adhesion receptors	1814:1831	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	20	theme	glycosylated	1722:1733	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	4	21	theme	mesenchymal	985:995	arg1	cells					1002:1006	mesenchymal stem cells	985:1006	mesenchymal stem cells	985:1006	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	21	theme	mesenchymal	985:995	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	7	22	gly	glycosylated	1722:1733	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	6	23	theme	vimentin-coated	1301:1315	arg1	surfaces					1317:1324	vimentin-coated surfaces	1301:1324	vimentin-coated surfaces	1301:1324	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	7	24	theme	receptors	1823:1831	arg1	class					1805:1809	a novel class	1797:1809	a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties	1797:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	25	theme	cell	1735:1738	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	6	26	theme	HA	1382:1383	arg1	synthase					1385:1392	HA synthase	1382:1392	HA synthase inhibitors	1382:1403	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	1	27	theme	vimentin	400:407	arg1	oligomers					409:417	vimentin oligomers	400:417	vimentin oligomers	400:417	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	2	28	theme	fibrotic	717:724	arg1	phenotype					726:734	a fibrotic phenotype	715:734	a fibrotic phenotype	715:734	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	6	29	theme	synthase	1385:1392	arg1	inhibitors					1394:1403	HA synthase inhibitors	1382:1403	HA synthase inhibitors	1382:1403	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	2	30	theme	extracellular	487:499	arg1	space					501:505	the extracellular space	483:505	the extracellular space	483:505	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	5	31	theme	force	1141:1145	arg1	microscopy					1147:1156	traction force microscopy	1132:1156	traction force microscopy	1132:1156	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	2	32	theme	cellular	658:665	arg1	activation					686:695	activation	686:695	activation of fibroblasts to a fibrotic phenotype	686:734	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	2	32	theme	cellular	658:665	arg1	functions					667:675	cellular functions	658:675	cellular functions	658:675	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	4	33	dep	types	940:944	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	33	dep	types	940:944	arg1	normal					947:952	normal	947:952	normal	947:952	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	33	dep	types	940:944	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	33	dep	types	940:944	arg1	cells					1002:1006	mesenchymal stem cells	985:1006	mesenchymal stem cells	985:1006	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	6	34	theme	collagen-coated	1532:1546	arg1	hydrogels					1548:1556	collagen-coated hydrogels	1532:1556	collagen-coated hydrogels	1532:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	0	35	theme	Extracellular	0:12	arg1	vimentin					14:21	Extracellular vimentin	0:21	Extracellular vimentin	0:21	Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures.					
37356720	3	36	theme	cell	798:801	arg1	membranes					803:811	external cell membranes	789:811	external cell membranes	789:811	The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized.					
37356720	5	37	theme	different	1209:1217	arg1	types					1224:1228	different cell types	1209:1228	different cell types	1209:1228	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	0	38	theme	N-acetyl	114:121	arg1	structures					146:155	N-acetyl glucosamine-containing structures	114:155	N-acetyl glucosamine-containing structures	114:155	Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures.					
37356720	2	39	theme	fibroblasts	700:710	arg1	activation					686:695	activation	686:695	activation of fibroblasts to a fibrotic phenotype	686:734	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	1	40	theme	cytoskeleton	207:218	arg1	part					195:198	part	195:198	part of the cytoskeleton of mesenchymal cells	195:239	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	1	41	theme	vimentin	312:319	arg1	filaments					321:329	vimentin filaments	312:329	vimentin filaments	312:329	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	7	42	theme	adhesive	1950:1957	arg1	properties					1959:1968	the glycocalyx adhesive properties	1935:1968	the glycocalyx adhesive properties	1935:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	5	43	theme	cell	1219:1222	arg1	types					1224:1228	different cell types	1209:1228	different cell types	1209:1228	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	2	44	from	changes	647:653	arg1	activation					686:695	activation	686:695	activation of fibroblasts to a fibrotic phenotype	686:734	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	2	44	from	changes	647:653	arg1	functions					667:675	cellular functions	658:675	cellular functions	658:675	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	4	45	theme	carcinoma	1019:1027	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	45	theme	carcinoma	1019:1027	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	3	46	theme	external	789:796	arg1	membranes					803:811	external cell membranes	789:811	external cell membranes	789:811	The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized.					
37356720	4	47	theme	vimentin	958:965	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	47	theme	vimentin	958:965	arg1	cells					1002:1006	mesenchymal stem cells	985:1006	mesenchymal stem cells	985:1006	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	47	theme	vimentin	958:965	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	6	48	theme	cell	1510:1513	arg1	types					1515:1519	the same cell types	1501:1519	the same cell types binding to collagen-coated hydrogels	1501:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	1	49	theme	mesenchymal	223:233	arg1	cells					235:239	mesenchymal cells	223:239	mesenchymal cells	223:239	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	4	50	theme	lung	1014:1017	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	50	theme	lung	1014:1017	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	0	51	theme	glucosamine-containing	123:144	arg1	structures					146:155	N-acetyl glucosamine-containing structures	114:155	N-acetyl glucosamine-containing structures	114:155	Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures.					
37356720	6	52	theme	degrading	1363:1371	arg1	enzymes					1373:1379	degrading enzymes	1363:1379	degrading enzymes	1363:1379	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	0	53	dep	cell	48:51	arg1	attachment					53:62	attachment	53:62	attachment	53:62	Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures.					
37356720	7	54	theme	cell	1893:1896	arg1	adhesion					1898:1905	cell adhesion	1893:1905	cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties	1893:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	1	55	theme	cells	235:239	arg1	cytoskeleton					207:218	the cytoskeleton	203:218	the cytoskeleton of mesenchymal cells	203:239	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	4	56	theme	various	927:933	arg1	types					940:944	various cell types	927:944	various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells)	927:1034	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	7	57	theme	carbohydrate	1668:1679	arg1	structures					1681:1690	carbohydrate structures	1668:1690	carbohydrate structures	1668:1690	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	57	theme	carbohydrate	1668:1679	arg1	proteins					1748:1755	glycosylated cell surface proteins	1722:1755	glycosylated cell surface proteins	1722:1755	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	57	theme	carbohydrate	1668:1679	arg1	glycocalyx					1707:1716	glycocalyx	1707:1716	glycocalyx	1707:1716	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	6	58	theme	Cell	1265:1268	arg1	attachment					1270:1279	Cell attachment	1265:1279	Cell attachment to	1265:1282	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	5	59	theme	traction	1132:1139	arg1	microscopy					1147:1156	traction force microscopy	1132:1156	traction force microscopy	1132:1156	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	5	60	theme	expansion	1171:1179	arg1	assays					1181:1186	spheroid expansion assays	1162:1186	spheroid expansion assays	1162:1186	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	6	61	theme	same	1505:1508	arg1	types					1515:1519	the same cell types	1501:1519	the same cell types binding to collagen-coated hydrogels	1501:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	7	62	theme	novel	1799:1803	arg1	class					1805:1809	a novel class	1797:1809	a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties	1797:1968	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	2	63	theme	extracellular	602:614	arg1	vimentin					616:623	extracellular vimentin	602:623	extracellular vimentin	602:623	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	5	64	theme	extracellular	1241:1253	arg1	vimentin					1255:1262	extracellular vimentin	1241:1262	extracellular vimentin	1241:1262	Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin.					
37356720	6	65	from	effect	1491:1496	arg1	types					1515:1519	the same cell types	1501:1519	the same cell types binding to collagen-coated hydrogels	1501:1556	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	7	66	theme	vimentin	1620:1627	arg1	effectiveness					1587:1599	the effectiveness	1583:1599	the effectiveness of substrate-bound vimentin	1583:1627	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	7	66	theme	vimentin	1620:1627	arg1	ligand					1634:1639	a ligand	1632:1639	a ligand for cells	1632:1649	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	4	67	theme	cell	935:938	arg1	types					940:944	various cell types	927:944	various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells)	927:1034	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	1	68	theme	extracellular	453:465	arg1	environment					467:477	the extracellular environment	449:477	the extracellular environment	449:477	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	7	69	dep	glycocalyx	1707:1716	arg1	the					1703:1705	the	1703:1705	the	1703:1705	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	4	70	theme	null	967:970	arg1	cells					1029:1033	A549 lung carcinoma cells	1009:1033	A549 lung carcinoma cells	1009:1033	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	70	theme	null	967:970	arg1	cells					1002:1006	mesenchymal stem cells	985:1006	mesenchymal stem cells	985:1006	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	70	theme	null	967:970	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	7	71	theme	N-acetyl	1770:1777	arg1	glucosamine					1779:1789	N-acetyl glucosamine	1770:1789	N-acetyl glucosamine	1770:1789	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	2	72	theme	cells	538:542	arg1	surfaces					526:533	surfaces	526:533	surfaces of cells and the extracellular matrix	526:571	In the extracellular space, vimentin can bind surfaces of cells and the extracellular matrix, and the interaction between extracellular vimentin and cells can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype.					
37356720	6	73	theme	N-acetyl	1426:1433	arg1	glucosamine					1435:1445	N-acetyl glucosamine	1426:1445	N-acetyl glucosamine	1426:1445	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	6	74	from	attachment	1270:1279	arg1	surfaces					1317:1324	vimentin-coated surfaces	1301:1324	vimentin-coated surfaces	1301:1324	Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine (GlcNAc), treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels.					
37356720	4	75	theme	stem	997:1000	arg1	cells					1002:1006	mesenchymal stem cells	985:1006	mesenchymal stem cells	985:1006	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	4	75	theme	stem	997:1000	arg1	fibroblasts					972:982	vimentin null fibroblasts	958:982	vimentin null fibroblasts	958:982	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	7	76	theme	substrate-bound	1604:1618	arg1	vimentin					1620:1627	substrate-bound vimentin	1604:1627	substrate-bound vimentin	1604:1627	These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin that can either directly support cell adhesion to a substrate or fine-tune the glycocalyx adhesive properties.					
37356720	1	77	theme	Vimentin	158:165	arg1	filaments					180:188	Vimentin intermediate filaments	158:188	Vimentin intermediate filaments	158:188	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
37356720	4	78	theme	polyacrylamide	1060:1073	arg1	substrates					1084:1093	polyacrylamide hydrogel substrates	1060:1093	polyacrylamide hydrogel substrates covalently linked to vimentin	1060:1123	Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin.					
37356720	1	79	theme	pathological	252:263	arg1	conditions					265:274	pathological conditions	252:274	pathological conditions often associated with inflammation	252:309	Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment.					
36621734	6	0	theme	molecular	1403:1411	arg1	chains					1413:1418	NR molecular chains	1400:1418	NR molecular chains	1400:1418	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	8	1	theme	mechanical	1765:1774	arg1	properties					1776:1785	physical and mechanical properties	1752:1785	the best physical and mechanical properties	1743:1785	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	4	2	theme	paramagnetic	854:865	arg1	resonance					867:875	Electron paramagnetic resonance	845:875	Electron paramagnetic resonance	845:875	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	9	3	theme	chemical	1837:1844	arg1	CNCs					1856:1859	CNCs	1856:1859	CNCs affecting NR vulcanization	1856:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	9	3	theme	chemical	1837:1844	arg1	groups					1846:1851	the surface chemical groups	1825:1851	the surface chemical groups of CNCs affecting NR vulcanization	1825:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	6	4	theme	ionic	1531:1535	arg1	reaction					1537:1544	ionic reaction	1531:1544	ionic reaction	1531:1544	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	5	theme	chemical	275:282	arg1	groups					284:289	their surface chemical groups	261:289	their surface chemical groups	261:289	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	6	from	effects	302:308	arg1	densities					355:363	cross-linking densities	341:363	cross-linking densities	341:363	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	6	from	effects	302:308	arg1	properties					381:390	mechanical properties	370:390	mechanical properties	370:390	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	6	from	effects	302:308	arg1	kinetics					331:338	the vulcanization kinetics	313:338	the vulcanization kinetics	313:338	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	0	7	theme	surface	15:21	arg1	groups					32:37	the surface chemical groups	11:37	the surface chemical groups of cellulose nanocrystals	11:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	0	7	theme	surface	15:21	arg1	nanocrystals					52:63	cellulose nanocrystals	42:63	cellulose nanocrystals	42:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	8	8	theme	higher	1673:1678	arg1	density					1694:1700	the higher cross-linking density	1669:1700	the higher cross-linking density	1669:1700	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	6	9	theme	CCP	1306:1308	arg1	polyethyleneimine					1285:1301	the polyethyleneimine	1281:1301	the polyethyleneimine of CCP	1281:1308	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	5	10	theme	radical	1047:1053	arg1	reactions					1055:1063	radical reactions	1047:1063	radical reactions	1047:1063	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	6	11	theme	strong	1448:1453	arg1	ability					1468:1474	a strong nucleophilic ability	1446:1474	a strong nucleophilic ability	1446:1474	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	12	theme	promising	207:215	arg1	effects					302:308	vital effects	296:308	vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites	296:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	12	theme	promising	207:215	arg1	fillers					229:235	the promising reinforcing fillers	203:235	the promising reinforcing fillers in the rubber industry	203:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	0	13	theme	nanocrystals	140:151	arg1	nanocomposites					153:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	6	14	theme	bonds	1381:1385	arg1	breaking					1357:1364	the breaking	1353:1364	the breaking of polysulfide bonds connected to NR molecular chains	1353:1418	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	6	14	theme	bonds	1381:1385	arg1	S8					1346:1347	S8	1346:1347	S8	1346:1347	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	6	14	theme	bonds	1381:1385	arg1	sulfur					1338:1343	sulfur	1338:1343	sulfur (S8)	1338:1348	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	7	15	theme	vulcanization	1558:1570	arg1	rate					1572:1575	vulcanization rate	1558:1575	vulcanization rate	1558:1575	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	3	16	theme	amino	715:719	arg1	groups					721:726	alkaline amino groups	706:726	alkaline amino groups	706:726	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	5	17	theme	NR/CCA	1007:1012	arg1	nanocomposites					1014:1027	NR/CCA nanocomposites	1007:1027	NR/CCA nanocomposites	1007:1027	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	3	18	theme	NR	761:762	arg1	vulcanization					744:756	the vulcanization	740:756	the vulcanization of NR	740:762	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	6	19	theme	amino	1265:1269	arg1	groups					1271:1276	The amino groups	1261:1276	The amino groups of the polyethyleneimine of CCP	1261:1308	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	6	19	theme	amino	1265:1269	arg1	polyethyleneimine					1285:1301	the polyethyleneimine	1281:1301	the polyethyleneimine of CCP	1281:1308	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	20	theme	rubber	244:249	arg1	industry					251:258	the rubber industry	240:258	the rubber industry	240:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	6	21	theme	NR/CCP	1513:1518	arg1	cross-linking					1496:1508	the cross-linking	1492:1508	the cross-linking of NR/CCP reacts via ionic reaction	1492:1544	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	6	22	dep	NR/CCP	1513:1518	arg1	reacts					1520:1525	reacts	1520:1525	reacts via ionic reaction	1520:1544	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	4	23	theme	groups	950:955	arg1	mechanisms					923:932	the effecting mechanisms	909:932	the effecting mechanisms of CNCs surface groups on NR vulcanization	909:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	4	24	from	mechanisms	923:932	arg1	vulcanization					963:975	NR vulcanization	960:975	NR vulcanization	960:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	7	25	dep	rate	1572:1575	arg1	The					1554:1556	The	1554:1556	The	1554:1556	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	4	26	dep	Fourier	800:806	arg1	transform					808:816	transform	808:816	transform infrared spectroscopy	808:838	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	1	27	theme	Cellulose	169:177	arg1	CNCs					193:196	CNCs	193:196	CNCs	193:196	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	27	theme	Cellulose	169:177	arg1	nanocrystals					179:190	Cellulose nanocrystals	169:190	Cellulose nanocrystals (CNCs)	169:197	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	4	28	theme	NR	960:961	arg1	vulcanization					963:975	NR vulcanization	960:975	NR vulcanization	960:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	9	29	theme	rubber	1950:1955	arg1	composites					1957:1966	high-performance rubber composites	1933:1966	high-performance rubber composites reinforced by CNCs	1933:1985	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	6	30	theme	sulfur	1338:1343	arg1	opening					1327:1333	the ring opening	1318:1333	the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly	1318:1551	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	8	31	theme	best	1747:1750	arg1	properties					1776:1785	physical and mechanical properties	1752:1785	the best physical and mechanical properties	1743:1785	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	5	32	dep	sulfonate	1128:1136	arg1	i.e.					1112:1115	i.e.	1112:1115	i.e.	1112:1115	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	7	33	theme	ionic	1633:1637	arg1	reaction					1639:1646	the ionic reaction	1629:1646	the ionic reaction	1629:1646	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	4	34	theme	CNCs	937:940	arg1	groups					950:955	CNCs surface groups	937:955	CNCs surface groups on NR vulcanization	937:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	5	35	theme	acidic	1082:1087	arg1	CCS					1099:1101	CCS	1099:1101	CCS	1099:1101	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	35	theme	acidic	1082:1087	arg1	groups					1089:1094	the surface acidic groups	1070:1094	the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups	1070:1157	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	35	theme	acidic	1082:1087	arg1	CCA					1107:1109	CCA	1107:1109	CCA	1107:1109	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	2	36	theme	acidic	432:437	arg1	CCA					449:451	CCA	449:451	CCA	449:451	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	2	36	theme	acidic	432:437	arg1	carboxyl					439:446	acidic carboxyl	432:446	acidic carboxyl (CCA)	432:452	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	6	37	theme	polysulfide	1369:1379	arg1	bonds					1381:1385	polysulfide bonds	1369:1385	polysulfide bonds connected to NR molecular chains	1369:1418	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	38	theme	vital	296:300	arg1	effects					302:308	vital effects	296:308	vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites	296:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	38	theme	vital	296:300	arg1	fillers					229:235	the promising reinforcing fillers	203:235	the promising reinforcing fillers in the rubber industry	203:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	3	39	theme	obvious	619:625	arg1	effects					638:644	obvious inhibiting effects	619:644	obvious inhibiting effects	619:644	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	4	40	theme	scanning	778:785	arg1	calorimeter					787:797	Differential scanning calorimeter	765:797	Differential scanning calorimeter	765:797	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	6	41	theme	breaking	1357:1364	arg1	opening					1327:1333	the ring opening	1318:1333	the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly	1318:1551	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	0	42	theme	chemical	23:30	arg1	groups					32:37	the surface chemical groups	11:37	the surface chemical groups of cellulose nanocrystals	11:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	0	42	theme	chemical	23:30	arg1	nanocrystals					52:63	cellulose nanocrystals	42:63	cellulose nanocrystals	42:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	2	43	theme	alkaline	458:465	arg1	amino					467:471	alkaline amino	458:471	alkaline amino	458:471	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	0	44	theme	nanocrystals	52:63	arg1	groups					32:37	the surface chemical groups	11:37	the surface chemical groups of cellulose nanocrystals	11:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	0	44	theme	nanocrystals	52:63	arg1	nanocrystals					52:63	cellulose nanocrystals	42:63	cellulose nanocrystals	42:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	1	45	theme	vulcanization	317:329	arg1	kinetics					331:338	the vulcanization kinetics	313:338	the vulcanization kinetics	313:338	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	8	46	from	density	1694:1700	arg1	benefiting					1653:1662	benefiting	1653:1662	benefiting from the higher cross-linking density	1653:1700	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	8	46	from	density	1694:1700	arg1	reinforcement					1710:1722	the reinforcement	1706:1722	the reinforcement of CCP, NR/CCP	1706:1737	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	5	47	theme	sulfur	1174:1179	arg1	radicals					1181:1188	the sulfur radicals	1170:1188	the sulfur radicals generated during vulcanization	1170:1219	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	4	48	from	groups	950:955	arg1	vulcanization					963:975	NR vulcanization	960:975	NR vulcanization	960:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	3	49	theme	rubber	678:683	arg1	vulcanization					653:665	the vulcanization	649:665	the vulcanization of natural rubber (NR)	649:688	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	5	50	theme	carboxyl	1143:1150	arg1	groups					1152:1157	hydroxyl, sulfonate, and carboxyl groups	1118:1157	groups	1152:1157	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	51	theme	CCS	1099:1101	arg1	CCS					1099:1101	CCS	1099:1101	CCS	1099:1101	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	51	theme	CCS	1099:1101	arg1	groups					1089:1094	the surface acidic groups	1070:1094	the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups	1070:1157	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	51	theme	CCS	1099:1101	arg1	CCA					1107:1109	CCA	1107:1109	CCA	1107:1109	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	9	52	theme	surface	1829:1835	arg1	CNCs					1856:1859	CNCs	1856:1859	CNCs affecting NR vulcanization	1856:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	9	52	theme	surface	1829:1835	arg1	groups					1846:1851	the surface chemical groups	1825:1851	the surface chemical groups of CNCs affecting NR vulcanization	1825:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	6	53	theme	NR	1400:1401	arg1	chains					1413:1418	NR molecular chains	1400:1418	NR molecular chains	1400:1418	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	54	theme	surface	267:273	arg1	groups					284:289	their surface chemical groups	261:289	their surface chemical groups	261:289	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	2	55	with	CNCs	422:425	arg1	CCP					481:483	CCP	481:483	CCP	481:483	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	2	55	with	CNCs	422:425	arg1	groups					473:478	acidic carboxyl (CCA) and alkaline amino groups	432:478	acidic carboxyl (CCA) and alkaline amino groups (CCP)	432:484	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	4	56	theme	Electron	845:852	arg1	resonance					867:875	Electron paramagnetic resonance	845:875	Electron paramagnetic resonance	845:875	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	9	57	theme	groups	1846:1851	arg1	mechanism					1812:1820	the mechanism	1808:1820	the mechanism of the surface chemical groups of CNCs affecting NR vulcanization	1808:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	1	58	contain	have	291:294	arg2	fillers					229:235	the promising reinforcing fillers	203:235	the promising reinforcing fillers in the rubber industry	203:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	58	contain	have	291:294	arg2	effects					302:308	vital effects	296:308	vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites	296:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	58	contain	have	291:294	arg1	groups					284:289	their surface chemical groups	261:289	their surface chemical groups	261:289	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	58	contain	have	291:294	arg1	nanocrystals					179:190	Cellulose nanocrystals	169:190	Cellulose nanocrystals (CNCs)	169:197	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	58	contain	have	291:294	arg1	CNCs					193:196	CNCs	193:196	CNCs	193:196	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	9	59	theme	CNCs	1856:1859	arg1	CNCs					1856:1859	CNCs	1856:1859	CNCs affecting NR vulcanization	1856:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	9	59	theme	CNCs	1856:1859	arg1	groups					1846:1851	the surface chemical groups	1825:1851	the surface chemical groups of CNCs affecting NR vulcanization	1825:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	4	60	from	vulcanization	963:975	arg1	mechanisms					923:932	the effecting mechanisms	909:932	the effecting mechanisms of CNCs surface groups on NR vulcanization	909:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	7	61	theme	cross-linking	1581:1593	arg1	density					1595:1601	cross-linking density	1581:1601	cross-linking density	1581:1601	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	9	62	theme	NR	1871:1872	arg1	vulcanization					1874:1886	NR vulcanization	1871:1886	NR vulcanization	1871:1886	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	3	63	theme	alkaline	706:713	arg1	groups					721:726	alkaline amino groups	706:726	alkaline amino groups	706:726	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	0	64	theme	rubber/cellulose	123:138	arg1	nanocomposites					153:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	6	65	theme	nucleophilic	1455:1466	arg1	ability					1468:1474	a strong nucleophilic ability	1446:1474	a strong nucleophilic ability	1446:1474	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	3	66	dep	CCS	585:587	arg1	the					581:583	the	581:583	the	581:583	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	0	67	theme	nanocomposites	153:166	arg1	vulcanization					72:84	vulcanization	72:84	vulcanization	72:84	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	0	67	theme	nanocomposites	153:166	arg1	properties					101:110	mechanical properties	90:110	mechanical properties	90:110	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	1	68	theme	composites	402:411	arg1	effects					302:308	vital effects	296:308	vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites	296:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	68	theme	composites	402:411	arg1	fillers					229:235	the promising reinforcing fillers	203:235	the promising reinforcing fillers in the rubber industry	203:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	8	69	theme	cross-linking	1680:1692	arg1	density					1694:1700	the higher cross-linking density	1669:1700	the higher cross-linking density	1669:1700	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	1	70	theme	reinforcing	217:227	arg1	effects					302:308	vital effects	296:308	vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites	296:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	1	70	theme	reinforcing	217:227	arg1	fillers					229:235	the promising reinforcing fillers	203:235	the promising reinforcing fillers in the rubber industry	203:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	2	71	theme	sulfonic	517:524	arg1	CCS					532:534	CCS	532:534	CCS	532:534	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	2	71	theme	sulfonic	517:524	arg1	CNCs					526:529	the sulfonic CNCs	513:529	the sulfonic CNCs (CCS)	513:535	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	3	72	contain	have	614:617	arg2	effects					638:644	obvious inhibiting effects	619:644	obvious inhibiting effects	619:644	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	3	72	contain	have	614:617	arg1	Studies					567:573	Studies	567:573	Studies found the CCS and CCA with acid groups	567:612	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	1	73	from	fillers	229:235	arg1	industry					251:258	the rubber industry	240:258	the rubber industry	240:258	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	0	74	from	Effects	0:6	arg1	vulcanization					72:84	vulcanization	72:84	vulcanization	72:84	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	0	74	from	Effects	0:6	arg1	properties					101:110	mechanical properties	90:110	mechanical properties	90:110	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	2	75	theme	environment-friendly	540:559	arg1	ways					561:564	environment-friendly ways	540:564	environment-friendly ways	540:564	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	5	76	theme	vulcanization	1237:1249	arg1	activity					1251:1258	the vulcanization activity	1233:1258	the vulcanization activity	1233:1258	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	3	77	with	CCS	585:587	arg1	groups					607:612	acid groups	602:612	acid groups	602:612	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	8	78	theme	CCP	1727:1729	arg1	benefiting					1653:1662	benefiting	1653:1662	benefiting from the higher cross-linking density	1653:1700	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	8	78	theme	CCP	1727:1729	arg1	reinforcement					1710:1722	the reinforcement	1706:1722	the reinforcement of CCP, NR/CCP	1706:1737	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	4	79	theme	surface	942:948	arg1	groups					950:955	CNCs surface groups	937:955	CNCs surface groups on NR vulcanization	937:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	9	80	theme	high-performance	1933:1948	arg1	composites					1957:1966	high-performance rubber composites	1933:1966	high-performance rubber composites reinforced by CNCs	1933:1985	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	3	81	with	CCA	593:595	arg1	groups					607:612	acid groups	602:612	acid groups	602:612	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	1	82	theme	cross-linking	341:353	arg1	densities					355:363	cross-linking densities	341:363	cross-linking densities	341:363	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	0	83	theme	natural	115:121	arg1	nanocomposites					153:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	natural rubber/cellulose nanocrystals nanocomposites	115:166	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	9	84	theme	composites	1957:1966	arg1	preparation					1918:1928	the preparation	1914:1928	the preparation of high-performance rubber composites reinforced by CNCs	1914:1985	Our work elucidates the mechanism of the surface chemical groups of CNCs affecting NR vulcanization and may provide ideas for the preparation of high-performance rubber composites reinforced by CNCs.					
36621734	1	85	theme	rubber	395:400	arg1	composites					402:411	rubber composites	395:411	rubber composites	395:411	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	0	86	theme	mechanical	90:99	arg1	properties					101:110	mechanical properties	90:110	mechanical properties	90:110	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	5	87	theme	CCA	1107:1109	arg1	CCS					1099:1101	CCS	1099:1101	CCS	1099:1101	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	87	theme	CCA	1107:1109	arg1	groups					1089:1094	the surface acidic groups	1070:1094	the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups	1070:1157	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	87	theme	CCA	1107:1109	arg1	CCA					1107:1109	CCA	1107:1109	CCA	1107:1109	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	4	88	theme	effecting	913:921	arg1	mechanisms					923:932	the effecting mechanisms	909:932	the effecting mechanisms of CNCs surface groups on NR vulcanization	909:975	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	6	89	theme	ring	1322:1325	arg1	opening					1327:1333	the ring opening	1318:1333	the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly	1318:1551	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	1	90	theme	mechanical	370:379	arg1	properties					381:390	mechanical properties	370:390	mechanical properties	370:390	Cellulose nanocrystals (CNCs), as the promising reinforcing fillers in the rubber industry, their surface chemical groups have vital effects on the vulcanization kinetics, cross-linking densities, and mechanical properties of rubber composites.					
36621734	8	91	theme	physical	1752:1759	arg1	properties					1776:1785	physical and mechanical properties	1752:1785	the best physical and mechanical properties	1743:1785	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	3	92	with	CCP	697:699	arg1	groups					721:726	alkaline amino groups	706:726	alkaline amino groups	706:726	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	0	93	dep	vulcanization	72:84	arg1	the					68:70	the	68:70	the	68:70	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	5	94	theme	surface	1074:1080	arg1	CCS					1099:1101	CCS	1099:1101	CCS	1099:1101	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	94	theme	surface	1074:1080	arg1	groups					1089:1094	the surface acidic groups	1070:1094	the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups	1070:1157	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	5	94	theme	surface	1074:1080	arg1	CCA					1107:1109	CCA	1107:1109	CCA	1107:1109	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	4	95	dep	transform	808:816	arg1	infrared					818:825	infrared	818:825	transform infrared spectroscopy	808:838	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	8	96	contain	had	1739:1741	arg1	benefiting					1653:1662	benefiting	1653:1662	benefiting from the higher cross-linking density	1653:1700	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	8	96	contain	had	1739:1741	arg1	reinforcement					1710:1722	the reinforcement	1706:1722	the reinforcement of CCP, NR/CCP	1706:1737	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	8	96	contain	had	1739:1741	arg2	properties					1776:1785	physical and mechanical properties	1752:1785	the best physical and mechanical properties	1743:1785	And benefiting from the higher cross-linking density and the reinforcement of CCP, NR/CCP had the best physical and mechanical properties.					
36621734	2	97	theme	carboxyl	439:446	arg1	CCP					481:483	CCP	481:483	CCP	481:483	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	2	97	theme	carboxyl	439:446	arg1	groups					473:478	acidic carboxyl (CCA) and alkaline amino groups	432:478	acidic carboxyl (CCA) and alkaline amino groups (CCP)	432:484	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	0	98	theme	groups	32:37	arg1	Effects					0:6	Effects	0:6	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.	0:167	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	7	99	theme	NR/CCP	1606:1611	arg1	rate					1572:1575	vulcanization rate	1558:1575	vulcanization rate	1558:1575	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	7	99	theme	NR/CCP	1606:1611	arg1	density					1595:1601	cross-linking density	1581:1601	cross-linking density	1581:1601	The vulcanization rate and cross-linking density of NR/CCP are improved by the ionic reaction.					
36621734	2	100	theme	amino	467:471	arg1	CCP					481:483	CCP	481:483	CCP	481:483	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	2	100	theme	amino	467:471	arg1	groups					473:478	acidic carboxyl (CCA) and alkaline amino groups	432:478	acidic carboxyl (CCA) and alkaline amino groups (CCP)	432:484	Herein, CNCs with acidic carboxyl (CCA) and alkaline amino groups (CCP) were produced by modifying the sulfonic CNCs (CCS) in environment-friendly ways.					
36621734	3	101	theme	acid	602:605	arg1	groups					607:612	acid groups	602:612	acid groups	602:612	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	4	102	theme	Differential	765:776	arg1	calorimeter					787:797	Differential scanning calorimeter	765:797	Differential scanning calorimeter	765:797	Differential scanning calorimeter, Fourier transform infrared spectroscopy, and Electron paramagnetic resonance, etc. were performed to clarify the effecting mechanisms of CNCs surface groups on NR vulcanization.					
36621734	0	103	theme	cellulose	42:50	arg1	nanocrystals					52:63	cellulose nanocrystals	42:63	cellulose nanocrystals	42:63	Effects of the surface chemical groups of cellulose nanocrystals on the vulcanization and mechanical properties of natural rubber/cellulose nanocrystals nanocomposites.					
36621734	6	104	theme	polyethyleneimine	1285:1301	arg1	groups					1271:1276	The amino groups	1261:1276	The amino groups of the polyethyleneimine of CCP	1261:1308	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	6	104	theme	polyethyleneimine	1285:1301	arg1	polyethyleneimine					1285:1301	the polyethyleneimine	1281:1301	the polyethyleneimine of CCP	1281:1308	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	5	105	theme	hydroxyl	1118:1125	arg1	sulfonate					1128:1136	hydroxyl, sulfonate, and carboxyl groups	1118:1157	sulfonate	1128:1136	It was found that NR/CCS and NR/CCA nanocomposites vulcanize through radical reactions, and the surface acidic groups of CCS and CCA, i.e., hydroxyl, sulfonate, and carboxyl groups inactivate the sulfur radicals generated during vulcanization and depress the vulcanization activity.					
36621734	3	106	theme	inhibiting	627:636	arg1	effects					638:644	obvious inhibiting effects	619:644	obvious inhibiting effects	619:644	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	6	107	theme	sulfur	1428:1433	arg1	anion					1435:1439	sulfur anion	1428:1439	sulfur anion	1428:1439	The amino groups of the polyethyleneimine of CCP promote the ring opening of sulfur (S8) or the breaking of polysulfide bonds connected to NR molecular chains to form sulfur anion with a strong nucleophilic ability, which leads to the cross-linking of NR/CCP reacts via ionic reaction mainly.					
36621734	3	108	theme	natural	670:676	arg1	NR					686:687	NR	686:687	NR	686:687	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36621734	3	108	theme	natural	670:676	arg1	rubber					678:683	natural rubber	670:683	natural rubber (NR)	670:688	Studies found the CCS and CCA with acid groups have obvious inhibiting effects on the vulcanization of natural rubber (NR), while CCP with alkaline amino groups accelerates the vulcanization of NR.					
36259357	9	0	theme	alleviated	1442:1451	arg1	properties					1476:1485	the alleviated in vitro antibacterial properties	1438:1485	the alleviated in vitro antibacterial properties	1438:1485	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	3	1	theme	clinical	513:520	arg1	application					522:532	the clinical application	509:532	the clinical application of AGs	509:539	However, the principal limitation in the clinical application of AGs arises from their high toxicity, including nephrotoxicity and ototoxicity.					
36259357	6	2	theme	3	1077:1077	arg1	absence					1051:1057	The absence	1047:1057	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs	1047:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	0	3	theme	Inducer	113:119	arg1	Activity					121:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	6	4	theme	AGs	1170:1172	arg1	moiety					1160:1165	the third sugar moiety	1144:1165	the third sugar moiety of AGs	1144:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	1	5	theme	bacterial	198:206	arg1	infections					208:217	bacterial infections	198:217	bacterial infections	198:217	Aminoglycosides (AGs) are broad-spectrum antibiotics used to treat bacterial infections.					
36259357	7	6	theme	in vitro	1274:1281	arg1	nephrotoxicity					1283:1296	the in vitro nephrotoxicity	1270:1296	the in vitro nephrotoxicity of AGs in mammalian cell lines	1270:1327	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	4	7	theme	KanM2	838:842	arg1	glycosyltransferase					844:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	2	8	theme	genetic	310:316	arg1	disorders					318:326	genetic disorders	310:326	genetic disorders caused by nonsense mutations	310:355	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	9	9	theme	novel	1654:1658	arg1	activity					1535:1542	the highest ex vivo NRI activity	1511:1542	the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1511:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	9	theme	novel	1654:1658	arg1	hit					1663:1665	a novel AG hit	1652:1665	a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination	1652:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	6	10	theme	1-N-acylation	1062:1074	arg1	absence					1051:1057	The absence	1047:1057	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs	1047:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	9	11	theme	premature	1724:1732	arg1	termination					1750:1760	premature transcriptional termination	1724:1760	premature transcriptional termination	1724:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	12	dep	highest	1515:1521	arg1	vivo					1526:1529	vivo	1526:1529	vivo	1526:1529	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	3	13	theme	high	559:562	arg1	toxicity					564:571	their high toxicity	553:571	their high toxicity	553:571	However, the principal limitation in the clinical application of AGs arises from their high toxicity, including nephrotoxicity and ototoxicity.					
36259357	9	14	theme	NRI	1531:1533	arg1	activity					1535:1542	the highest ex vivo NRI activity	1511:1542	the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1511:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	14	theme	NRI	1531:1533	arg1	hit					1663:1665	a novel AG hit	1652:1665	a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination	1652:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	5	15	theme	readthrough	990:1000	arg1	inducer					1002:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer	945:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	5	15	theme	readthrough	990:1000	arg1	NRI					1011:1013	NRI	1011:1013	NRI	1011:1013	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	9	16	theme	transcriptional	1734:1748	arg1	termination					1750:1760	premature transcriptional termination	1724:1760	premature transcriptional termination	1724:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	5	17	theme	biological	912:921	arg1	activities					923:932	biological activities	912:932	biological activities	912:932	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	5	17	theme	biological	912:921	arg1	activities					1016:1025	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	4	18	theme	substrate-flexible	819:836	arg1	glycosyltransferase					844:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	9	19	theme	highest	1515:1521	arg1	activity					1535:1542	the highest ex vivo NRI activity	1511:1542	the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1511:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	19	theme	highest	1515:1521	arg1	hit					1663:1665	a novel AG hit	1652:1665	a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination	1652:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	6	20	theme	transfer	1118:1125	arg1	modifications					1127:1139	post-glycosyl transfer modifications	1104:1139	post-glycosyl transfer modifications	1104:1139	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	5	21	theme	nonsense	981:988	arg1	inducer					1002:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer	945:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	5	21	theme	nonsense	981:988	arg1	NRI					1011:1013	NRI	1011:1013	NRI	1011:1013	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	6	22	theme	antibacterial	1191:1203	arg1	activities					1205:1214	their antibacterial activities	1185:1214	their antibacterial activities	1185:1214	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	8	23	theme	6'-methyl	1354:1362	arg1	scaffolds					1364:1372	4'-dihydroxy and 6'-methyl scaffolds	1337:1372	4'-dihydroxy and 6'-methyl scaffolds	1337:1372	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	8	23	theme	6'-methyl	1354:1362	arg1	3					1334:1334	3	1334:1334	3	1334:1334	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	0	24	theme	Chemo-enzymatic	0:14	arg1	Synthesis					16:24	Chemo-enzymatic Synthesis	0:24	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.	0:129	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	9	25	from	studies	1679:1685	arg1	disorders					1704:1712	human genetic disorders	1690:1712	human genetic disorders caused by premature transcriptional termination	1690:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	6	26	theme	third	1148:1152	arg1	moiety					1160:1165	the third sugar moiety	1144:1165	the third sugar moiety of AGs	1144:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	7	27	theme	6'-hydroxy	1241:1250	arg1	moieties					1252:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	7	28	theme	AGs	1301:1303	arg1	nephrotoxicity					1283:1296	the in vitro nephrotoxicity	1270:1296	the in vitro nephrotoxicity of AGs in mammalian cell lines	1270:1327	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	6	29	theme	sugar	1154:1158	arg1	moiety					1160:1165	the third sugar moiety	1144:1165	the third sugar moiety of AGs	1144:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	3	30	from	limitation	495:504	arg1	application					522:532	the clinical application	509:532	the clinical application of AGs	509:539	However, the principal limitation in the clinical application of AGs arises from their high toxicity, including nephrotoxicity and ototoxicity.					
36259357	2	31	theme	nonsense	338:345	arg1	mutations					347:355	nonsense mutations	338:355	nonsense mutations	338:355	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	5	32	theme	antibacterial	949:961	arg1	inducer					1002:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer	945:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	5	32	theme	antibacterial	949:961	arg1	NRI					1011:1013	NRI	1011:1013	NRI	1011:1013	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	2	33	theme	full-length	451:461	arg1	protein					463:469	a full-length protein	449:469	a full-length protein	449:469	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	8	34	theme	AGs	1424:1426	arg1	activity					1412:1419	the ex vivo NRI activity	1396:1419	the ex vivo NRI activity of AGs	1396:1426	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	4	35	theme	chemo-enzymatic	691:705	arg1	synthesis					707:715	chemo-enzymatic synthesis	691:715	chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs	691:764	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	0	36	theme	Pseudo-trisaccharide	29:48	arg1	Antibiotics					65:75	Pseudo-trisaccharide Aminoglycoside Antibiotics	29:75	Pseudo-trisaccharide Aminoglycoside Antibiotics	29:75	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	4	37	theme	enzymatic	782:790	arg1	reaction					792:799	an enzymatic reaction	779:799	an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase	779:862	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	2	38	from	potential	273:281	arg1	treatment					297:305	the treatment	293:305	the treatment of genetic disorders caused by nonsense mutations	293:355	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	4	39	theme	pseudo-trisaccharide	642:661	arg1	analogs					663:669	five novel pseudo-trisaccharide analogs	631:669	five novel pseudo-trisaccharide analogs	631:669	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	8	40	dep	ex	1400:1401	arg1	vivo					1403:1406	vivo	1403:1406	vivo	1403:1406	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	2	41	theme	disorders	318:326	arg1	treatment					297:305	the treatment	293:305	the treatment of genetic disorders caused by nonsense mutations	293:355	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	4	42	theme	novel	636:640	arg1	analogs					663:669	five novel pseudo-trisaccharide analogs	631:669	five novel pseudo-trisaccharide analogs	631:669	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	0	43	theme	Antibiotics	65:75	arg1	Synthesis					16:24	Chemo-enzymatic Synthesis	0:24	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.	0:129	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	6	44	from	absence	1051:1057	arg1	moiety					1160:1165	the third sugar moiety	1144:1165	the third sugar moiety of AGs	1144:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	8	45	theme	4'-dihydroxy	1337:1348	arg1	scaffolds					1364:1372	4'-dihydroxy and 6'-methyl scaffolds	1337:1372	4'-dihydroxy and 6'-methyl scaffolds	1337:1372	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	8	45	theme	4'-dihydroxy	1337:1348	arg1	3					1334:1334	3	1334:1334	3	1334:1334	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	7	46	from	nephrotoxicity	1283:1296	arg1	lines					1323:1327	mammalian cell lines	1308:1327	mammalian cell lines	1308:1327	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	6	47	theme	post-glycosyl	1104:1116	arg1	modifications					1127:1139	post-glycosyl transfer modifications	1104:1139	post-glycosyl transfer modifications	1104:1139	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	0	48	theme	Aminoglycoside	50:63	arg1	Antibiotics					65:75	Pseudo-trisaccharide Aminoglycoside Antibiotics	29:75	Pseudo-trisaccharide Aminoglycoside Antibiotics	29:75	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	7	49	theme	4'-dihydroxy	1224:1235	arg1	moieties					1252:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	0	50	theme	Enhanced	82:89	arg1	Activity					121:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	5	51	theme	nephrotoxic	964:974	arg1	inducer					1002:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer	945:1008	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	5	51	theme	nephrotoxic	964:974	arg1	NRI					1011:1013	NRI	1011:1013	NRI	1011:1013	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	8	52	theme	NRI	1408:1410	arg1	activity					1412:1419	the ex vivo NRI activity	1396:1419	the ex vivo NRI activity of AGs	1396:1426	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	7	53	theme	mammalian	1308:1316	arg1	lines					1323:1327	mammalian cell lines	1308:1327	mammalian cell lines	1308:1327	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	9	54	theme	kanamycin	1572:1580	arg1	compounds					1559:1567	the five compounds	1550:1567	the five compounds	1550:1567	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	54	theme	kanamycin	1572:1580	arg1	analog					1582:1587	a kanamycin analog	1570:1587	a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1570:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	54	theme	kanamycin	1572:1580	arg1	C					1633:1633		-1:1633		-1:1633	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	4	55	theme	available	752:760	arg1	AGs					762:764	commercially available AGs	739:764	commercially available AGs	739:764	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	7	56	theme	3	1221:1221	arg1	moieties					1252:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties	1217:1259	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	9	57	theme	6'-methyl-3"-deamino-3"-hydroxykanamycin	-1:38	arg1	analog					1582:1587	a kanamycin analog	1570:1587	a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1570:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	57	theme	6'-methyl-3"-deamino-3"-hydroxykanamycin	-1:38	arg1	C					1633:1633		-1:1633		-1:1633	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	58	theme	further	1671:1677	arg1	studies					1679:1685	further studies	1671:1685	further studies on human genetic disorders caused by premature transcriptional termination	1671:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	0	59	with	Synthesis	16:24	arg1	Activity					121:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	5	60	theme	inducer	1002:1008	arg1	activities					1016:1025	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities	945:1025	The relationships between their structures and biological activities, including the antibacterial, nephrotoxic, and nonsense readthrough inducer (NRI) activities, were investigated.					
36259357	9	61	theme	genetic	1696:1702	arg1	disorders					1704:1712	human genetic disorders	1690:1712	human genetic disorders caused by premature transcriptional termination	1690:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	6	62	theme	4'-dideoxygenation	1080:1097	arg1	absence					1051:1057	The absence	1047:1057	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs	1047:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	3	63	theme	principal	485:493	arg1	limitation					495:504	the principal limitation	481:504	the principal limitation in the clinical application of AGs	481:539	However, the principal limitation in the clinical application of AGs arises from their high toxicity, including nephrotoxicity and ototoxicity.					
36259357	4	64	theme	recombinant	807:817	arg1	glycosyltransferase					844:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	recombinant substrate-flexible KanM2 glycosyltransferase	807:862	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	2	65	theme	AGs	286:288	arg1	potential					273:281	the potential	269:281	the potential of AGs in the treatment of genetic disorders caused by nonsense mutations	269:355	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	9	66	theme	in vitro	1453:1460	arg1	properties					1476:1485	the alleviated in vitro antibacterial properties	1438:1485	the alleviated in vitro antibacterial properties	1438:1485	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	4	67	theme	AGs	762:764	arg1	hydrolysis					725:734	acid hydrolysis	720:734	acid hydrolysis of commercially available AGs	720:764	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	8	68	theme	ex	1400:1401	arg1	activity					1412:1419	the ex vivo NRI activity	1396:1419	the ex vivo NRI activity of AGs	1396:1426	The 3',4'-dihydroxy and 6'-methyl scaffolds are indispensable for the ex vivo NRI activity of AGs.					
36259357	1	69	theme	broad-spectrum	157:170	arg1	Aminoglycosides					131:145	Aminoglycosides	131:145	Aminoglycosides (AGs)	131:151	Aminoglycosides (AGs) are broad-spectrum antibiotics used to treat bacterial infections.					
36259357	1	69	theme	broad-spectrum	157:170	arg1	antibiotics					172:182	broad-spectrum antibiotics	157:182	broad-spectrum antibiotics used to treat bacterial infections	157:217	Aminoglycosides (AGs) are broad-spectrum antibiotics used to treat bacterial infections.					
36259357	0	70	theme	Read-through	100:111	arg1	Activity					121:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	2	71	theme	last	229:232	arg1	decades					238:244	the last two decades	225:244	the last two decades	225:244	Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by nonsense mutations, owing to their ability to induce the ribosomes to read through these mutations and produce a full-length protein.					
36259357	9	72	theme	human	1690:1694	arg1	disorders					1704:1712	human genetic disorders	1690:1712	human genetic disorders caused by premature transcriptional termination	1690:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	6	73	theme	modifications	1127:1139	arg1	absence					1051:1057	The absence	1047:1057	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs	1047:1172	The absence of 1-N-acylation, 3',4'-dideoxygenation, and post-glycosyl transfer modifications on the third sugar moiety of AGs diminishes their antibacterial activities.					
36259357	4	74	theme	acid	720:723	arg1	hydrolysis					725:734	acid hydrolysis	720:734	acid hydrolysis of commercially available AGs	720:764	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	9	75	theme	AG	1660:1661	arg1	activity					1535:1542	the highest ex vivo NRI activity	1511:1542	the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C)	1511:1634	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	9	75	theme	AG	1660:1661	arg1	hit					1663:1665	a novel AG hit	1652:1665	a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination	1652:1760	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
36259357	0	76	theme	Nonsense	91:98	arg1	Activity					121:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Enhanced Nonsense Read-through Inducer Activity	82:128	Chemo-enzymatic Synthesis of Pseudo-trisaccharide Aminoglycoside Antibiotics with Enhanced Nonsense Read-through Inducer Activity.					
36259357	4	77	dep	synthesized	676:686	arg1	followed					767:774	followed	767:774	followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase	767:862	In this study, five novel pseudo-trisaccharide analogs were synthesized by chemo-enzymatic synthesis by acid hydrolysis of commercially available AGs, followed by an enzymatic reaction using recombinant substrate-flexible KanM2 glycosyltransferase.					
36259357	3	78	theme	AGs	537:539	arg1	application					522:532	the clinical application	509:532	the clinical application of AGs	509:539	However, the principal limitation in the clinical application of AGs arises from their high toxicity, including nephrotoxicity and ototoxicity.					
36259357	7	79	theme	cell	1318:1321	arg1	lines					1323:1327	mammalian cell lines	1308:1327	mammalian cell lines	1308:1327	The 3',4'-dihydroxy and 6'-hydroxy moieties regulate the in vitro nephrotoxicity of AGs in mammalian cell lines.					
36259357	9	80	theme	antibacterial	1462:1474	arg1	properties					1476:1485	the alleviated in vitro antibacterial properties	1438:1485	the alleviated in vitro antibacterial properties	1438:1485	Based on the alleviated in vitro antibacterial properties and nephrotoxicity, and the highest ex vivo NRI activity among the five compounds, a kanamycin analog (6'-methyl-3''-deamino-3''-hydroxykanamycin C) was selected as a novel AG hit for further studies on human genetic disorders caused by premature transcriptional termination.					
35183667	1	0	theme	key	141:143	arg1	role					145:148	a key role	139:148	a key role in human health	139:164	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	6	1	theme	gradient	931:938	arg1	electrophoresis					944:958	notably temporal temperature gradient gel electrophoresis	902:958	notably temporal temperature gradient gel electrophoresis	902:958	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	6	1	theme	gradient	931:938	arg1	microbiota					890:899	the microbiota	886:899	the microbiota (notably temporal temperature gradient gel electrophoresis)	886:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	0	2	theme	microbiota	67:76	arg1	endpoints					78:86	selected microbiota endpoints	58:86	selected microbiota endpoints in the SHIME® model	58:106	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	9	3	from	impact	1466:1471	arg1	homeostasis					1487:1497	the body's homeostasis	1476:1497	the body's homeostasis	1476:1497	Given the known role of host-microbiota communication, CPF's impact on the body's homeostasis remains to be determined.					
35183667	6	4	theme	temperature	919:929	arg1	electrophoresis					944:958	notably temporal temperature gradient gel electrophoresis	902:958	notably temporal temperature gradient gel electrophoresis	902:958	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	6	4	theme	temperature	919:929	arg1	microbiota					890:899	the microbiota	886:899	the microbiota (notably temporal temperature gradient gel electrophoresis)	886:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	0	5	from	Effect	0:5	arg1	endpoints					78:86	selected microbiota endpoints	58:86	selected microbiota endpoints in the SHIME® model	58:106	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	1	6	from	role	145:148	arg1	health					159:164	human health	153:164	human health	153:164	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	1	7	theme	digestive	227:235	arg1	environment					243:253	the digestive tract environment	223:253	the digestive tract environment	223:253	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	5	8	theme	dynamic	676:682	arg1	model					693:697	The SHIME® dynamic in vitro model	665:697	The SHIME® dynamic in vitro model of the human intestine	665:720	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	5	9	from	variations	798:807	arg1	populations					831:841	the bacterial populations	817:841	the bacterial populations	817:841	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	5	9	from	variations	798:807	arg1	metabolites					853:863	their metabolites	847:863	their metabolites	847:863	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	8	10	theme	saccharolytic	1270:1282	arg1	bacteria					1284:1291	the saccharolytic bacteria	1266:1291	the saccharolytic bacteria in general	1266:1302	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	1	11	theme	tract	237:241	arg1	environment					243:253	the digestive tract environment	223:253	the digestive tract environment	223:253	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	5	12	theme	in	684:685	arg1	model					693:697	The SHIME® dynamic in vitro model	665:697	The SHIME® dynamic in vitro model of the human intestine	665:720	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	3	13	contain	has	422:424	arg2	contaminant					376:386	a food contaminant	369:386	a food contaminant	369:386	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	13	contain	has	422:424	arg1	CPF					417:419	CPF	417:419	CPF	417:419	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	13	contain	has	422:424	arg1	chlorpyrifos					403:414	the pesticide chlorpyrifos	389:414	the pesticide chlorpyrifos (CPF)	389:420	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	13	contain	has	422:424	arg2	effect					429:434	an effect	426:434	an effect on the composition of the intestinal microbiota	426:482	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	14	theme	intestinal	462:471	arg1	microbiota					473:482	the intestinal microbiota	458:482	the intestinal microbiota	458:482	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	8	15	from	bacteria	1284:1291	arg1	general					1296:1302	general	1296:1302	general	1296:1302	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	2	16	theme	diversity	355:363	arg1	Food					256:259	Food	256:259	Food	256:259	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	2	16	theme	diversity	355:363	arg1	regulator					331:339	a key regulator	325:339	a key regulator of microbiota diversity	325:363	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	0	17	theme	SHIME®	95:100	arg1	model					102:106	the SHIME® model	91:106	the SHIME® model	91:106	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	3	18	theme	microbiota	473:482	arg1	composition					443:453	the composition	439:453	the composition of the intestinal microbiota	439:482	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	1	19	theme	human	153:157	arg1	health					159:164	human health	153:164	human health	153:164	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	1	20	contain	has	135:137	arg2	role					145:148	a key role	139:148	a key role in human health	139:164	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	1	20	contain	has	135:137	arg1	microbiota					124:133	The intestinal microbiota	109:133	The intestinal microbiota	109:133	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	3	21	theme	microbiota	512:521	arg1	perturbation					496:507	perturbation	496:507	perturbation of microbiota	496:521	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	8	22	from	increase	1327:1334	arg1	levels					1339:1344	levels	1339:1344	levels of short-chain fatty acids and more specifically butyrate	1339:1402	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	6	23	theme	prebiotic	997:1005	arg1	effect					983:988	a protective effect	970:988	a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population	970:1068	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	3	24	from	effect	429:434	arg1	composition					443:453	the composition	439:453	the composition of the intestinal microbiota	439:482	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	0	25	theme	co-exposure	16:26	arg1	Effect					0:5	Effect	0:5	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.	0:107	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	6	26	theme	microbiota	890:899	arg1	analyses					874:881	Various analyses	866:881	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis)	866:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	2	27	theme	matrix	270:275	arg1	effect					277:282	matrix effect	270:282	matrix effect	270:282	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	0	28	theme	daily	10:14	arg1	co-exposure					16:26	daily co-exposure	10:26	daily co-exposure to inulin and chlorpyrifos	10:53	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	9	29	theme	communication	1445:1457	arg1	role					1421:1424	the known role	1411:1424	the known role of host-microbiota communication	1411:1457	Given the known role of host-microbiota communication, CPF's impact on the body's homeostasis remains to be determined.					
35183667	0	30	from	endpoints	78:86	arg1	model					102:106	the SHIME® model	91:106	the SHIME® model	91:106	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	4	31	theme	microbiota	617:626	arg1	equilibrium					598:608	an equilibrium	595:608	an equilibrium of the microbiota that favours saccharolytic bacteria	595:662	Prebiotics (and notably inulin) are known for their ability to promote an equilibrium of the microbiota that favours saccharolytic bacteria.					
35183667	5	32	theme	intestine	712:720	arg1	model					693:697	The SHIME® dynamic in vitro model	665:697	The SHIME® dynamic in vitro model of the human intestine	665:720	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	4	33	theme	saccharolytic	641:653	arg1	bacteria					655:662	saccharolytic bacteria	641:662	saccharolytic bacteria	641:662	Prebiotics (and notably inulin) are known for their ability to promote an equilibrium of the microbiota that favours saccharolytic bacteria.					
35183667	9	34	theme	host-microbiota	1429:1443	arg1	communication					1445:1457	host-microbiota communication	1429:1457	host-microbiota communication	1429:1457	Given the known role of host-microbiota communication, CPF's impact on the body's homeostasis remains to be determined.					
35183667	9	35	theme	known	1415:1419	arg1	role					1421:1424	the known role	1411:1424	the known role of host-microbiota communication	1411:1457	Given the known role of host-microbiota communication, CPF's impact on the body's homeostasis remains to be determined.					
35183667	6	36	theme	protective	972:981	arg1	effect					983:988	a protective effect	970:988	a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population	970:1068	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	3	37	theme	food	371:374	arg1	effect					429:434	an effect	426:434	an effect on the composition of the intestinal microbiota	426:482	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	37	theme	food	371:374	arg1	contaminant					376:386	a food contaminant	369:386	a food contaminant	369:386	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	1	38	with	interaction	174:184	arg1	cells					214:218	the somatic and immune cells	191:218	cells	214:218	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	6	39	theme	Various	866:872	arg1	analyses					874:881	Various analyses	866:881	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis)	866:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	5	40	dep	in	684:685	arg1	vitro					687:691	vitro	687:691	vitro	687:691	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	8	41	theme	butyrate	1395:1402	arg1	levels					1339:1344	levels	1339:1344	levels of short-chain fatty acids and more specifically butyrate	1339:1402	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	5	42	theme	bacterial	821:829	arg1	populations					831:841	the bacterial populations	817:841	the bacterial populations	817:841	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	8	43	theme	other	1156:1160	arg1	lactobacilli					1198:1209	lactobacilli	1198:1209	lactobacilli	1198:1209	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	8	43	theme	other	1156:1160	arg1	populations					1185:1195	other potentially beneficial populations	1156:1195	other potentially beneficial populations (lactobacilli)	1156:1210	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	6	44	dep	enterobacterial	1033:1047	arg1	coli					1053:1056	E. coli	1050:1056	E. coli	1050:1056	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	2	45	theme	non-nutrient	298:309	arg1	molecules					311:319	non-nutrient molecules	298:319	non-nutrient molecules	298:319	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	8	46	theme	fatty	1361:1365	arg1	acids					1367:1371	short-chain fatty acids	1349:1371	short-chain fatty acids	1349:1371	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	1	47	from	interaction	174:184	arg1	environment					243:253	the digestive tract environment	223:253	the digestive tract environment	223:253	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	1	48	theme	intestinal	113:122	arg1	microbiota					124:133	The intestinal microbiota	109:133	The intestinal microbiota	109:133	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	1	49	theme	somatic	195:201	arg1	cells					214:218	the somatic and immune cells	191:218	cells	214:218	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	8	50	theme	short-chain	1349:1359	arg1	acids					1367:1371	short-chain fatty acids	1349:1371	short-chain fatty acids	1349:1371	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	5	51	theme	human	706:710	arg1	intestine					712:720	the human intestine	702:720	the human intestine	702:720	The SHIME® dynamic in vitro model of the human intestine was exposed to CPF and inulin concomitantly for 30 days, in order to assess variations in both the bacterial populations and their metabolites.					
35183667	6	52	theme	population	1059:1068	arg1	inhibition					1015:1024	inhibition	1015:1024	inhibition of the enterobacterial (E. coli) population	1015:1068	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	3	53	theme	pesticide	393:401	arg1	CPF					417:419	CPF	417:419	CPF	417:419	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	3	53	theme	pesticide	393:401	arg1	chlorpyrifos					403:414	the pesticide chlorpyrifos	389:414	the pesticide chlorpyrifos (CPF)	389:420	As a food contaminant, the pesticide chlorpyrifos (CPF) has an effect on the composition of the intestinal microbiota and induces perturbation of microbiota.					
35183667	0	54	theme	selected	58:65	arg1	endpoints					78:86	selected microbiota endpoints	58:86	selected microbiota endpoints in the SHIME® model	58:106	Effect of daily co-exposure to inulin and chlorpyrifos on selected microbiota endpoints in the SHIME® model.					
35183667	4	55	dep	inulin	548:553	arg1	notably					540:546	notably	540:546	notably	540:546	Prebiotics (and notably inulin) are known for their ability to promote an equilibrium of the microbiota that favours saccharolytic bacteria.					
35183667	2	56	theme	key	327:329	arg1	Food					256:259	Food	256:259	Food	256:259	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	2	56	theme	key	327:329	arg1	regulator					331:339	a key regulator	325:339	a key regulator of microbiota diversity	325:363	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	2	57	theme	microbiota	344:353	arg1	diversity					355:363	microbiota diversity	344:363	microbiota diversity	344:363	Food, through matrix effect, nutrient and non-nutrient molecules, is a key regulator of microbiota diversity.					
35183667	1	58	theme	immune	207:212	arg1	cells					214:218	the somatic and immune cells	191:218	cells	214:218	The intestinal microbiota has a key role in human health via the interaction with the somatic and immune cells in the digestive tract environment.					
35183667	6	59	theme	temporal	910:917	arg1	electrophoresis					944:958	notably temporal temperature gradient gel electrophoresis	902:958	notably temporal temperature gradient gel electrophoresis	902:958	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	6	59	theme	temporal	910:917	arg1	microbiota					890:899	the microbiota	886:899	the microbiota (notably temporal temperature gradient gel electrophoresis)	886:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	8	60	theme	beneficial	1174:1183	arg1	lactobacilli					1198:1209	lactobacilli	1198:1209	lactobacilli	1198:1209	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	8	60	theme	beneficial	1174:1183	arg1	populations					1185:1195	other potentially beneficial populations	1156:1195	other potentially beneficial populations (lactobacilli)	1156:1210	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	8	61	theme	acids	1367:1371	arg1	levels					1339:1344	levels	1339:1344	levels of short-chain fatty acids and more specifically butyrate	1339:1402	Although other potentially beneficial populations (lactobacilli) were not greatly modified, their activity and that of the saccharolytic bacteria in general were highlighted by an increase in levels of short-chain fatty acids and more specifically butyrate.					
35183667	6	62	theme	enterobacterial	1033:1047	arg1	population					1059:1068	the enterobacterial (E. coli) population	1029:1068	the enterobacterial (E. coli) population	1029:1068	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	6	63	theme	gel	940:942	arg1	electrophoresis					944:958	notably temporal temperature gradient gel electrophoresis	902:958	notably temporal temperature gradient gel electrophoresis	902:958	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
35183667	6	63	theme	gel	940:942	arg1	microbiota					890:899	the microbiota	886:899	the microbiota (notably temporal temperature gradient gel electrophoresis)	886:959	Various analyses of the microbiota (notably temporal temperature gradient gel electrophoresis) revealed a protective effect of the prebiotic through inhibition of the enterobacterial (E. coli) population.					
36417571	0	0	theme	SARS-CoV-2	56:65	arg1	Case					67:70	The SARS-CoV-2 Case	52:70	The SARS-CoV-2 Case	52:70	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	8	1	theme	steric	924:929	arg1	repulsion					931:939	the glycan steric repulsion	913:939	the glycan steric repulsion that a virus	913:952	On the other side, the glycan steric repulsion that a virus must overcome to approach such specific receptors.					
36417571	1	2	theme	cell	128:131	arg1	surfaces					145:152	the cell and protein surfaces	124:152	surfaces	145:152	Glycans are ubiquitously expressed sugars, coating the cell and protein surfaces.					
36417571	10	3	theme	virus	1134:1138	arg1	infection					1140:1148	virus infection	1134:1148	virus infection in terms of receptors and proteoglycans compositions	1134:1201	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	0	4	from	Role	4:7	arg1	Infectivity					39:49	Virus Infectivity	33:49	Virus Infectivity	33:49	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	8	5	theme	glycan	917:922	arg1	repulsion					931:939	the glycan steric repulsion	913:939	the glycan steric repulsion that a virus	913:952	On the other side, the glycan steric repulsion that a virus must overcome to approach such specific receptors.					
36417571	4	6	theme	host	510:513	arg1	surface					490:496	the surface	486:496	the surface of both the host and virus proteins	486:532	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	3	7	theme	sugar	312:316	arg1	glycocalyx					331:340	the glycocalyx	327:340	the glycocalyx	327:340	This sugar cushion, the glycocalyx, modulates specific interactions and protects the cell.					
36417571	3	7	theme	sugar	312:316	arg1	cushion					318:324	This sugar cushion	307:324	This sugar cushion	307:324	This sugar cushion, the glycocalyx, modulates specific interactions and protects the cell.					
36417571	4	8	theme	proteins	525:532	arg1	surface					490:496	the surface	486:496	the surface of both the host and virus proteins	486:532	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	7	9	theme	specific	857:864	arg1	glycans					871:877	specific host glycans	857:877	specific host glycans	857:877	On one side, the multivalent molecular recognition that viral proteins have toward specific host glycans and receptors.					
36417571	2	10	theme	sticking	238:245	arg1	chains					216:221	either short and branched chains	190:221	either short and branched chains	190:221	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	10	11	theme	receptors	1162:1170	arg1	terms					1153:1157	terms	1153:1157	terms of receptors and proteoglycans compositions	1153:1201	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	4	12	theme	virus	519:523	arg1	proteins					525:532	both the host and virus proteins	501:532	proteins	525:532	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	7	13	theme	host	866:869	arg1	glycans					871:877	specific host glycans	857:877	specific host glycans	857:877	On one side, the multivalent molecular recognition that viral proteins have toward specific host glycans and receptors.					
36417571	1	14	theme	protein	137:143	arg1	surfaces					145:152	the cell and protein surfaces	124:152	surfaces	145:152	Glycans are ubiquitously expressed sugars, coating the cell and protein surfaces.					
36417571	0	15	dep	Case	67:70	arg1	Role					4:7	The Role	0:7	The Role of Host Cell Glycans on Virus Infectivity	0:49	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	8	16	theme	other	901:905	arg1	side					907:910	the other side	897:910	the other side	897:910	On the other side, the glycan steric repulsion that a virus must overcome to approach such specific receptors.					
36417571	7	17	theme	viral	830:834	arg1	proteins					836:843	viral proteins	830:843	viral proteins	830:843	On one side, the multivalent molecular recognition that viral proteins have toward specific host glycans and receptors.					
36417571	2	18	theme	membrane	264:271	arg1	proteins					273:280	special membrane proteins	256:280	special membrane proteins	256:280	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	2	19	located	found	164:168	arg1	proteins					178:185	many proteins	173:185	many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans	173:304	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	2	19	located	found	164:168	arg2	They					155:158	They	155:158	They	155:158	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	0	20	theme	Host	12:15	arg1	Glycans					22:28	Host Cell Glycans	12:28	Host Cell Glycans	12:28	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	4	21	contain	have	534:537	arg2	role					550:553	a critical role	539:553	a critical role	539:553	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	4	21	contain	have	534:537	arg1	glycans					465:471	the glycans	461:471	the glycans expressed on the surface of both the host and virus proteins	461:532	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	4	21	contain	have	534:537	arg1	expression					429:438	the expression	425:438	the expression of proteoglycans	425:455	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	2	22	theme	special	256:262	arg1	proteins					273:280	special membrane proteins	256:280	special membrane proteins	256:280	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	10	23	theme	proteoglycans	1176:1188	arg1	terms					1153:1157	terms	1153:1157	terms of receptors and proteoglycans compositions	1153:1201	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	0	24	theme	Glycans	22:28	arg1	Role					4:7	The Role	0:7	The Role of Host Cell Glycans on Virus Infectivity	0:49	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	8	25	theme	specific	985:992	arg1	receptors					994:1002	such specific receptors	980:1002	such specific receptors	980:1002	On the other side, the glycan steric repulsion that a virus must overcome to approach such specific receptors.					
36417571	2	26	theme	short	197:201	arg1	chains					216:221	either short and branched chains	190:221	either short and branched chains	190:221	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	0	27	theme	Cell	17:20	arg1	Glycans					22:28	Host Cell Glycans	12:28	Host Cell Glycans	12:28	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	5	28	theme	archetypical	643:654	arg1	virus					656:660	an archetypical virus	640:660	an archetypical virus to study the glycan role during infection	640:702	A mathematical model using SARS-Cov-2 as an archetypical virus to study the glycan role during infection is proposed.					
36417571	5	28	theme	archetypical	643:654	arg1	SARS-Cov-2					626:635	SARS-Cov-2	626:635	SARS-Cov-2	626:635	A mathematical model using SARS-Cov-2 as an archetypical virus to study the glycan role during infection is proposed.					
36417571	6	29	theme	forces	766:771	arg1	tug-of-war					752:761	a tug-of-war	750:761	a tug-of-war of forces	750:771	It is shown that this occurs via a tug-of-war of forces.					
36417571	4	30	theme	viral	569:573	arg1	attachment					575:584	viral attachment	569:584	viral attachment to the cell	569:596	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	0	31	theme	Virus	33:37	arg1	Infectivity					39:49	Virus Infectivity	33:49	Virus Infectivity	33:49	The Role of Host Cell Glycans on Virus Infectivity: The SARS-CoV-2 Case.					
36417571	3	32	theme	specific	353:360	arg1	interactions					362:373	specific interactions	353:373	specific interactions	353:373	This sugar cushion, the glycocalyx, modulates specific interactions and protects the cell.					
36417571	5	33	theme	mathematical	601:612	arg1	model					614:618	A mathematical model	599:618	A mathematical model using SARS-Cov-2 as an archetypical virus to study the glycan role during infection	599:702	A mathematical model using SARS-Cov-2 as an archetypical virus to study the glycan role during infection is proposed.					
36417571	2	34	theme	many	173:176	arg1	proteins					178:185	many proteins	173:185	many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans	173:304	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	1	35	theme	expressed	98:106	arg1	sugars					108:113	ubiquitously expressed sugars	85:113	ubiquitously expressed sugars	85:113	Glycans are ubiquitously expressed sugars, coating the cell and protein surfaces.					
36417571	1	35	theme	expressed	98:106	arg1	Glycans					73:79	Glycans	73:79	Glycans	73:79	Glycans are ubiquitously expressed sugars, coating the cell and protein surfaces.					
36417571	9	36	theme	viral	1037:1041	arg1	tropism					1043:1049	viral tropism	1037:1049	viral tropism	1037:1049	By balancing both interactions, viral tropism can be predicted.					
36417571	2	37	dep	proteins	273:280	arg1	out					247:249	out	247:249	out	247:249	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	10	38	from	infection	1140:1148	arg1	terms					1153:1157	terms	1153:1157	terms of receptors and proteoglycans compositions	1153:1201	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	2	39	theme	long	226:229	arg1	chains					231:236	long chains	226:236	long chains	226:236	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	7	40	theme	multivalent	791:801	arg1	recognition					813:823	the multivalent molecular recognition	787:823	the multivalent molecular recognition that viral proteins	787:843	On one side, the multivalent molecular recognition that viral proteins have toward specific host glycans and receptors.					
36417571	10	41	theme	other	1072:1076	arg1	words					1078:1082	other words	1072:1082	other words	1072:1082	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	5	42	theme	glycan	675:680	arg1	role					682:685	the glycan role	671:685	the glycan role	671:685	A mathematical model using SARS-Cov-2 as an archetypical virus to study the glycan role during infection is proposed.					
36417571	2	43	theme	branched	207:214	arg1	chains					216:221	either short and branched chains	190:221	either short and branched chains	190:221	They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.					
36417571	7	44	theme	molecular	803:811	arg1	recognition					813:823	the multivalent molecular recognition	787:823	the multivalent molecular recognition that viral proteins	787:843	On one side, the multivalent molecular recognition that viral proteins have toward specific host glycans and receptors.					
36417571	4	45	theme	proteoglycans	443:455	arg1	glycans					465:471	the glycans	461:471	the glycans expressed on the surface of both the host and virus proteins	461:532	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	4	45	theme	proteoglycans	443:455	arg1	expression					429:438	the expression	425:438	the expression of proteoglycans	425:455	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
36417571	10	46	dep	receptors	1162:1170	arg1	compositions					1190:1201	compositions	1190:1201	compositions	1190:1201	In other words, the authors can map out the cells susceptible to virus infection in terms of receptors and proteoglycans compositions.					
36417571	8	47	theme	such	980:983	arg1	receptors					994:1002	such specific receptors	980:1002	such specific receptors	980:1002	On the other side, the glycan steric repulsion that a virus must overcome to approach such specific receptors.					
36417571	4	48	theme	critical	541:548	arg1	role					550:553	a critical role	539:553	a critical role	539:553	Here it is shown that both the expression of proteoglycans and the glycans expressed on the surface of both the host and virus proteins have a critical role in modulating viral attachment to the cell.					
35107857	10	0	theme	inulin	1468:1473	arg1	evident					1530:1536	evident	1530:1536	evident	1530:1536	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	10	0	theme	inulin	1468:1473	arg1	effect					1458:1463	A pronounced effect	1445:1463	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract	1445:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	6	1	theme	markers	930:936	arg1	levels					915:920	lower serum levels	903:920	lower serum levels of bone markers	903:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	expression					949:958	lower expression	943:958	lower expression of calcium absorption-related genes	943:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	CaBP					1077:1080	CaBP	1077:1080	CaBP	1077:1080	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	strength					893:900	femur mechanical strength	876:900	femur mechanical strength	876:900	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	content					864:870	bone mineral content	851:870	bone mineral content	851:870	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	type					1036:1039	transient receptor potential vanilloid type 6	997:1041	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	protein					1068:1074	calcium-binding protein	1052:1074	calcium-binding protein (CaBP)	1052:1081	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	1	theme	markers	930:936	arg1	TRPV6					1044:1048	TRPV6	1044:1048	TRPV6	1044:1048	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	1	2	theme	health	133:138	arg1	challenge					140:148	a health challenge	131:148	a health challenge especially for postmenopausal women	131:184	SCOPE Osteoporosis poses a health challenge especially for postmenopausal women.					
35107857	5	3	theme	acids	669:673	arg1	abundance					691:699	the abundance	687:699	the abundance of fecal Acinetobacter and Propionibacterium	687:744	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	3	theme	acids	669:673	arg1	concentrations					633:646	intestinal concentrations	622:646	intestinal concentrations of short-chain fatty acids (SCFAs)	622:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	0	4	theme	Gut-Bone	50:57	arg1	Associations					59:70	Gut-Bone Associations	50:70	Gut-Bone Associations in an Ovarierectomized Rat Model	50:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	6	5	theme	mineral	834:840	arg1	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	6	theme	receptor	1007:1014	arg1	vanilloid					1026:1034	transient receptor potential vanilloid	997:1034	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	8	7	theme	spine	1363:1367	arg1	bone					1369:1372	spine bone	1363:1372	spine bone	1363:1372	Inulin and lactose show beneficial effects on spine bone.					
35107857	3	8	theme	=	337:337	arg1	n					335:335	n = 49	335:340	n = 49	335:340	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	8	theme	=	337:337	arg1	rats					329:332	OVX rats	325:332	METHODS AND RESULTS OVX rats (n = 49)	305:341	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	0	9	from	Effects	0:6	arg1	Associations					59:70	Gut-Bone Associations	50:70	Gut-Bone Associations in an Ovarierectomized Rat Model	50:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	2	10	theme	OVX	294:296	arg1	rats					299:302	ovarierectomized (OVX) rats	276:302	ovarierectomized (OVX) rats	276:302	This study aims to explore nutritional strategies to counteract bone demineralization in ovarierectomized (OVX) rats.					
35107857	8	11	theme	beneficial	1341:1350	arg1	effects					1352:1358	beneficial effects	1341:1358	beneficial effects on spine bone	1341:1372	Inulin and lactose show beneficial effects on spine bone.					
35107857	6	12	theme	serum	909:913	arg1	levels					915:920	lower serum levels	903:920	lower serum levels of bone markers	903:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	5	13	theme	short-chain	651:661	arg1	SCFAs					676:680	SCFAs	676:680	SCFAs	676:680	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	13	theme	short-chain	651:661	arg1	acids					669:673	short-chain fatty acids	651:673	short-chain fatty acids (SCFAs)	651:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	6	14	theme	higher	822:827	arg1	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	15	theme	potential	1016:1024	arg1	vanilloid					1026:1034	transient receptor potential vanilloid	997:1034	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	16	theme	lower	903:907	arg1	levels					915:920	lower serum levels	903:920	lower serum levels of bone markers	903:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	0	17	theme	Rat	95:97	arg1	Model					99:103	an Ovarierectomized Rat Model	75:103	an Ovarierectomized Rat Model	75:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	2	18	theme	ovarierectomized	276:291	arg1	rats					299:302	ovarierectomized (OVX) rats	276:302	ovarierectomized (OVX) rats	276:302	This study aims to explore nutritional strategies to counteract bone demineralization in ovarierectomized (OVX) rats.					
35107857	6	19	theme	genes	990:994	arg1	levels					915:920	lower serum levels	903:920	lower serum levels of bone markers	903:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	expression					949:958	lower expression	943:958	lower expression of calcium absorption-related genes	943:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	CaBP					1077:1080	CaBP	1077:1080	CaBP	1077:1080	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	strength					893:900	femur mechanical strength	876:900	femur mechanical strength	876:900	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	content					864:870	bone mineral content	851:870	bone mineral content	851:870	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	type					1036:1039	transient receptor potential vanilloid type 6	997:1041	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	protein					1068:1074	calcium-binding protein	1052:1074	calcium-binding protein (CaBP)	1052:1081	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	19	theme	genes	990:994	arg1	TRPV6					1044:1048	TRPV6	1044:1048	TRPV6	1044:1048	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	20	theme	transient	997:1005	arg1	vanilloid					1026:1034	transient receptor potential vanilloid	997:1034	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	0	21	theme	Ovarierectomized	78:93	arg1	Model					99:103	an Ovarierectomized Rat Model	75:103	an Ovarierectomized Rat Model	75:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	10	22	theme	bone	1636:1639	arg1	mineralization					1641:1654	slightly enhanced bone mineralization	1618:1654	slightly enhanced bone mineralization	1618:1654	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	10	23	theme	enhanced	1627:1634	arg1	mineralization					1641:1654	slightly enhanced bone mineralization	1618:1654	slightly enhanced bone mineralization	1618:1654	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	10	24	theme	jejunal	1577:1583	arg1	pH					1585:1586	jejunal pH	1577:1586	jejunal pH that might be associated with slightly enhanced bone mineralization	1577:1654	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	5	25	theme	fatty	663:667	arg1	SCFAs					676:680	SCFAs	676:680	SCFAs	676:680	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	25	theme	fatty	663:667	arg1	acids					669:673	short-chain fatty acids	651:673	short-chain fatty acids (SCFAs)	651:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	26	theme	Acinetobacter	710:722	arg1	abundance					691:699	the abundance	687:699	the abundance of fecal Acinetobacter and Propionibacterium	687:744	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	26	theme	Acinetobacter	710:722	arg1	concentrations					633:646	intestinal concentrations	622:646	intestinal concentrations of short-chain fatty acids (SCFAs)	622:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	6	27	theme	calcium-fortified	793:809	arg1	diets					811:815	calcium-fortified diets	793:815	calcium-fortified diets	793:815	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	7	28	theme	intestinal	1205:1214	arg1	pH					1216:1217	a decreased intestinal pH	1193:1217	a decreased intestinal pH	1193:1217	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	28	theme	intestinal	1205:1214	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	10	29	theme	metabolic	1478:1486	arg1	activity					1488:1495	metabolic activity	1478:1495	metabolic activity in the gastrointestinal tract	1478:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	10	30	theme	gastrointestinal	1504:1519	arg1	tract					1521:1525	the gastrointestinal tract	1500:1525	the gastrointestinal tract	1500:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	1	31	theme	postmenopausal	165:178	arg1	women					180:184	postmenopausal women	165:184	postmenopausal women	165:184	SCOPE Osteoporosis poses a health challenge especially for postmenopausal women.					
35107857	8	32	from	effects	1352:1358	arg1	bone					1369:1372	spine bone	1363:1372	spine bone	1363:1372	Inulin and lactose show beneficial effects on spine bone.					
35107857	4	33	theme	calcium-deficient	552:568	arg1	diet					570:573	a calcium-deficient diet	550:573	a calcium-deficient diet	550:573	In addition, a calcium-deficient diet is included.					
35107857	0	34	theme	Source	19:24	arg1	Effects					0:6	Effects	0:6	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model	0:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	6	35	theme	calcium-binding	1052:1066	arg1	protein					1068:1074	calcium-binding protein	1052:1074	calcium-binding protein (CaBP)	1052:1081	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	35	theme	calcium-binding	1052:1066	arg1	CaBP					1077:1080	CaBP	1077:1080	CaBP	1077:1080	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	36	theme	calcium	963:969	arg1	genes					990:994	calcium absorption-related genes	963:994	calcium absorption-related genes	963:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	0	37	theme	Calcium	11:17	arg1	Source					19:24	Calcium Source	11:24	Calcium Source	11:24	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	6	38	theme	mechanical	882:891	arg1	strength					893:900	femur mechanical strength	876:900	femur mechanical strength	876:900	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	3	39	dep	METHODS	305:311	arg1	n					335:335	n = 49	335:340	n = 49	335:340	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	39	dep	METHODS	305:311	arg1	rats					329:332	OVX rats	325:332	METHODS AND RESULTS OVX rats (n = 49)	305:341	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	0	40	from	Associations	59:70	arg1	Model					99:103	an Ovarierectomized Rat Model	75:103	an Ovarierectomized Rat Model	75:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	7	41	theme	increased	1223:1231	arg1	abundance					1233:1241	an increased abundance	1220:1241	an increased abundance of Allobaculum and Bifidobacterium	1220:1276	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	41	theme	increased	1223:1231	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	5	42	theme	Propionibacterium	728:744	arg1	abundance					691:699	the abundance	687:699	the abundance of fecal Acinetobacter and Propionibacterium	687:744	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	5	42	theme	Propionibacterium	728:744	arg1	concentrations					633:646	intestinal concentrations	622:646	intestinal concentrations of short-chain fatty acids (SCFAs)	622:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	0	43	theme	Inulin	27:32	arg1	Effects					0:6	Effects	0:6	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model	0:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	6	44	theme	femur	876:880	arg1	strength					893:900	femur mechanical strength	876:900	femur mechanical strength	876:900	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	5	45	theme	intestinal	622:631	arg1	concentrations					633:646	intestinal concentrations	622:646	intestinal concentrations of short-chain fatty acids (SCFAs)	622:681	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	6	46	contain	have	817:820	arg2	TRPV6					1044:1048	TRPV6	1044:1048	TRPV6	1044:1048	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	type					1036:1039	transient receptor potential vanilloid type 6	997:1041	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	protein					1068:1074	calcium-binding protein	1052:1074	calcium-binding protein (CaBP)	1052:1081	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	CaBP					1077:1080	CaBP	1077:1080	CaBP	1077:1080	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	expression					949:958	lower expression	943:958	lower expression of calcium absorption-related genes	943:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	levels					915:920	lower serum levels	903:920	lower serum levels of bone markers	903:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg1	rats					779:782	rats	779:782	rats fed with calcium-fortified diets	779:815	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	46	contain	have	817:820	arg2	content					864:870	bone mineral content	851:870	bone mineral content	851:870	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	47	theme	absorption-related	971:988	arg1	genes					990:994	calcium absorption-related genes	963:994	calcium absorption-related genes	963:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	3	48	theme	different	394:402	arg1	sources					412:418	two different calcium sources	390:418	two different calcium sources (dairy calcium or calcium carbonate)	390:455	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	48	theme	different	394:402	arg1	calcium					427:433	dairy calcium	421:433	dairy calcium	421:433	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	48	theme	different	394:402	arg1	carbonate					446:454	calcium carbonate	438:454	calcium carbonate	438:454	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	49	theme	different	367:375	arg1	diets					377:381	one of six different diets	356:381	one of six different diets	356:381	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	9	50	theme	gut	1404:1406	arg1	composition					1419:1429	gut microbiome composition	1404:1429	gut microbiome composition	1404:1429	CONCLUSION Calcium modulates gut microbiome composition and function.					
35107857	2	51	theme	nutritional	214:224	arg1	strategies					226:235	nutritional strategies	214:235	nutritional strategies to counteract bone demineralization in ovarierectomized (OVX) rats	214:302	This study aims to explore nutritional strategies to counteract bone demineralization in ovarierectomized (OVX) rats.					
35107857	3	52	theme	calcium	404:410	arg1	sources					412:418	two different calcium sources	390:418	two different calcium sources (dairy calcium or calcium carbonate)	390:455	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	52	theme	calcium	404:410	arg1	calcium					427:433	dairy calcium	421:433	dairy calcium	421:433	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	52	theme	calcium	404:410	arg1	carbonate					446:454	calcium carbonate	438:454	calcium carbonate	438:454	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	10	53	theme	lactose	1543:1549	arg1	supplementation					1551:1565	lactose supplementation	1543:1565	lactose supplementation	1543:1565	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	7	54	theme	Inulin	1106:1111	arg1	supplementation					1113:1127	Inulin supplementation	1106:1127	Inulin supplementation	1106:1127	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	5	55	theme	fecal	704:708	arg1	Acinetobacter					710:722	fecal Acinetobacter	704:722	fecal Acinetobacter	704:722	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	9	56	theme	microbiome	1408:1417	arg1	composition					1419:1429	gut microbiome composition	1404:1429	gut microbiome composition	1404:1429	CONCLUSION Calcium modulates gut microbiome composition and function.					
35107857	3	57	with	combination	482:492	arg1	inulin					506:511	inulin	506:511	inulin (5%)	506:516	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	57	with	combination	482:492	arg1	%					515:515	5%	514:515	5%	514:515	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	57	with	combination	482:492	arg1	lactose					521:527	lactose	521:527	lactose (0.5%)	521:534	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	57	with	combination	482:492	arg1	%					533:533	0.5%	530:533	0.5%	530:533	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	6	58	theme	mineral	856:862	arg1	content					864:870	bone mineral content	851:870	bone mineral content	851:870	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	10	59	theme	pronounced	1447:1456	arg1	evident					1530:1536	evident	1530:1536	evident	1530:1536	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	10	59	theme	pronounced	1447:1456	arg1	effect					1458:1463	A pronounced effect	1445:1463	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract	1445:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	7	60	theme	increased	1286:1294	arg1	expression					1296:1305	an increased expression	1283:1305	an increased expression of Trpv6	1283:1314	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	3	61	theme	calcium	438:444	arg1	sources					412:418	two different calcium sources	390:418	two different calcium sources (dairy calcium or calcium carbonate)	390:455	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	61	theme	calcium	438:444	arg1	carbonate					446:454	calcium carbonate	438:454	calcium carbonate	438:454	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	6	62	theme	bone	851:854	arg1	content					864:870	bone mineral content	851:870	bone mineral content	851:870	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	10	63	from	activity	1488:1495	arg1	tract					1521:1525	the gastrointestinal tract	1500:1525	the gastrointestinal tract	1500:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	1	64	theme	SCOPE	106:110	arg1	Osteoporosis					112:123	SCOPE Osteoporosis	106:123	SCOPE Osteoporosis	106:123	SCOPE Osteoporosis poses a health challenge especially for postmenopausal women.					
35107857	7	65	theme	Trpv6	1310:1314	arg1	expression					1296:1305	an increased expression	1283:1305	an increased expression of Trpv6	1283:1314	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	65	theme	Trpv6	1310:1314	arg1	production					1161:1170	a markedly increased production	1140:1170	a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium,	1140:1277	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	5	66	theme	Calcium	588:594	arg1	supplementation					596:610	Calcium supplementation	588:610	Calcium supplementation	588:610	Calcium supplementation increases intestinal concentrations of short-chain fatty acids (SCFAs) and the abundance of fecal Acinetobacter and Propionibacterium.					
35107857	7	67	theme	decreased	1195:1203	arg1	pH					1216:1217	a decreased intestinal pH	1193:1217	a decreased intestinal pH	1193:1217	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	67	theme	decreased	1195:1203	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	2	68	theme	bone	251:254	arg1	demineralization					256:271	bone demineralization	251:271	bone demineralization	251:271	This study aims to explore nutritional strategies to counteract bone demineralization in ovarierectomized (OVX) rats.					
35107857	7	69	theme	intestinal	1175:1184	arg1	abundance					1233:1241	an increased abundance	1220:1241	an increased abundance of Allobaculum and Bifidobacterium	1220:1276	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	69	theme	intestinal	1175:1184	arg1	pH					1216:1217	a decreased intestinal pH	1193:1217	a decreased intestinal pH	1193:1217	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	69	theme	intestinal	1175:1184	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	3	70	theme	dairy	421:425	arg1	sources					412:418	two different calcium sources	390:418	two different calcium sources (dairy calcium or calcium carbonate)	390:455	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	70	theme	dairy	421:425	arg1	calcium					427:433	dairy calcium	421:433	dairy calcium	421:433	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	71	theme	OVX	325:327	arg1	n					335:335	n = 49	335:340	n = 49	335:340	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	71	theme	OVX	325:327	arg1	rats					329:332	OVX rats	325:332	METHODS AND RESULTS OVX rats (n = 49)	305:341	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	6	72	theme	lower	943:947	arg1	expression					949:958	lower expression	943:958	lower expression of calcium absorption-related genes	943:994	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	3	73	dep	sources	412:418	arg1	sources					412:418	two different calcium sources	390:418	two different calcium sources (dairy calcium or calcium carbonate)	390:455	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	73	dep	sources	412:418	arg1	calcium					427:433	dairy calcium	421:433	dairy calcium	421:433	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	3	73	dep	sources	412:418	arg1	carbonate					446:454	calcium carbonate	438:454	calcium carbonate	438:454	METHODS AND RESULTS OVX rats (n = 49) are fed with one of six different diets, where two different calcium sources (dairy calcium or calcium carbonate) are provided alone or in combination with either inulin (5%) or lactose (0.5%).					
35107857	9	74	theme	CONCLUSION	1375:1384	arg1	Calcium					1386:1392	CONCLUSION Calcium	1375:1392	CONCLUSION Calcium	1375:1392	CONCLUSION Calcium modulates gut microbiome composition and function.					
35107857	7	75	theme	Allobaculum	1246:1256	arg1	abundance					1233:1241	an increased abundance	1220:1241	an increased abundance of Allobaculum and Bifidobacterium	1220:1276	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	75	theme	Allobaculum	1246:1256	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	6	76	theme	bone	829:832	arg1	density					842:848	higher bone mineral density	822:848	higher bone mineral density	822:848	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	0	77	theme	Lactose	39:45	arg1	Effects					0:6	Effects	0:6	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model	0:103	Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.					
35107857	10	78	from	effect	1458:1463	arg1	activity					1488:1495	metabolic activity	1478:1495	metabolic activity in the gastrointestinal tract	1478:1525	A pronounced effect of inulin on metabolic activity in the gastrointestinal tract is evident, and lactose supplementation decreases jejunal pH that might be associated with slightly enhanced bone mineralization.					
35107857	7	79	theme	Bifidobacterium	1262:1276	arg1	abundance					1233:1241	an increased abundance	1220:1241	an increased abundance of Allobaculum and Bifidobacterium	1220:1276	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	79	theme	Bifidobacterium	1262:1276	arg1	SCFAs					1186:1190	intestinal SCFAs	1175:1190	intestinal SCFAs	1175:1190	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	80	theme	SCFAs	1186:1190	arg1	expression					1296:1305	an increased expression	1283:1305	an increased expression of Trpv6	1283:1314	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	7	80	theme	SCFAs	1186:1190	arg1	production					1161:1170	a markedly increased production	1140:1170	a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium,	1140:1277	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	6	81	theme	vanilloid	1026:1034	arg1	type					1036:1039	transient receptor potential vanilloid type 6	997:1041	transient receptor potential vanilloid type 6 (TRPV6)	997:1049	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	6	81	theme	vanilloid	1026:1034	arg1	TRPV6					1044:1048	TRPV6	1044:1048	TRPV6	1044:1048	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35107857	7	82	theme	increased	1151:1159	arg1	production					1161:1170	a markedly increased production	1140:1170	a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium,	1140:1277	Inulin supplementation results in a markedly increased production of intestinal SCFAs, a decreased intestinal pH, an increased abundance of Allobaculum and Bifidobacterium, and an increased expression of Trpv6.					
35107857	6	83	theme	bone	925:928	arg1	markers					930:936	bone markers	925:936	bone markers	925:936	Accompanied with these effects, rats fed with calcium-fortified diets have higher bone mineral density, bone mineral content and femur mechanical strength, lower serum levels of bone markers, and lower expression of calcium absorption-related genes (transient receptor potential vanilloid type 6 (TRPV6), calcium-binding protein (CaBP) compared with control.					
35218225	8	0	theme	water	1256:1260	arg1	permeability					1268:1279	water vapor permeability	1256:1279	water vapor permeability	1256:1279	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	11	1	dep	1.3	1484:1486	arg1	to					1481:1482	to	1481:1482	to	1481:1482	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	11	2	theme	composite	1500:1508	arg1	stiffness					1457:1465	the stiffness	1453:1465	the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite	1453:1508	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	11	2	theme	composite	1500:1508	arg1	Gpa					1488:1490	from 3.1 GPa to 1.3 Gpa	1468:1490	from 3.1 GPa to 1.3 Gpa	1468:1490	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	11	3	dep	hydrophobicity	1386:1399	arg1	angle					1410:1414	contact angle	1402:1414	contact angle from 10-40° to 80-90°	1402:1436	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	6	4	theme	biodegradability	873:888	arg1	degree					844:849	high degree	839:849	high degree of hydrophobicity and biodegradability	839:888	Polyhydroxyalkanoate is a biopolymer with high degree of hydrophobicity and biodegradability, and is also obtained by fermentation.					
35218225	7	5	theme	Wet	929:931	arg1	membranes					937:945	Wet BNC membranes	929:945	Wet BNC membranes produced by static culture	929:972	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	13	6	theme	polyethylene	1697:1708	arg1	glycol					1710:1715	polyethylene glycol	1697:1715	polyethylene glycol	1697:1715	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	7	7	theme	solutions	1010:1018	arg1	impregnation					994:1005	impregnation	994:1005	impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG )	994:1089	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	2	8	theme	eco-friendly	314:325	arg1	materials					339:347	eco-friendly sustainable materials	314:347	eco-friendly sustainable materials that meet food-packaging requirements	314:385	The food industry increasingly needs eco-friendly sustainable materials that meet food-packaging requirements.					
35218225	2	9	theme	sustainable	327:337	arg1	materials					339:347	eco-friendly sustainable materials	314:347	eco-friendly sustainable materials that meet food-packaging requirements	314:385	The food industry increasingly needs eco-friendly sustainable materials that meet food-packaging requirements.					
35218225	5	10	theme	overall	769:775	arg1	properties					785:794	its overall barrier properties	765:794	its overall barrier properties	765:794	In this work, a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV) was produced, attempting to improve its overall barrier properties.					
35218225	13	11	theme	BNC	1721:1723	arg1	plasticizing					1666:1677	The plasticizing	1662:1677	The plasticizing (with glycerol or polyethylene glycol) of BNC	1662:1723	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	6	12	theme	hydrophobicity	854:867	arg1	degree					844:849	high degree	839:849	high degree of hydrophobicity and biodegradability	839:888	Polyhydroxyalkanoate is a biopolymer with high degree of hydrophobicity and biodegradability, and is also obtained by fermentation.					
35218225	1	13	theme	food	133:136	arg1	packaging					138:146	food packaging	133:146	food packaging	133:146	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	5	14	theme	barrier	777:783	arg1	properties					785:794	its overall barrier properties	765:794	its overall barrier properties	765:794	In this work, a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV) was produced, attempting to improve its overall barrier properties.					
35218225	5	15	theme	biodegradable	660:672	arg1	composite					674:682	a layered biodegradable composite	650:682	a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV)	650:727	In this work, a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV) was produced, attempting to improve its overall barrier properties.					
35218225	5	16	theme	layered	652:658	arg1	composite					674:682	a layered biodegradable composite	650:682	a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV)	650:727	In this work, a layered biodegradable composite based on BNC and polyhydroxyalkanoate (PHBV) was produced, attempting to improve its overall barrier properties.					
35218225	3	17	theme	mechanical	475:484	arg1	properties					486:495	very good mechanical properties	465:495	very good mechanical properties	465:495	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	13	18	theme	water	1808:1812	arg1	affinity					1814:1821	the water affinity	1804:1821	the water affinity (vapor and liquid state)	1804:1846	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	8	19	theme	plasticized	1096:1106	arg1	BNC					1108:1110	The plasticized BNC	1092:1110	The plasticized BNC	1092:1110	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	6	20	theme	high	839:842	arg1	degree					844:849	high degree	839:849	high degree of hydrophobicity and biodegradability	839:888	Polyhydroxyalkanoate is a biopolymer with high degree of hydrophobicity and biodegradability, and is also obtained by fermentation.					
35218225	1	21	theme	Most	95:98	arg1	BACKGROUND					84:93	BACKGROUND Most	84:98	BACKGROUND Most of the current materials used in food packaging	84:146	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	8	22	theme	vapor	1262:1266	arg1	permeability					1268:1279	water vapor permeability	1256:1279	water vapor permeability	1256:1279	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	11	23	theme	contact	1402:1408	arg1	angle					1410:1414	contact angle	1402:1414	contact angle from 10-40° to 80-90°	1402:1436	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	13	24	theme	mechanical	1752:1761	arg1	performance					1763:1773	the mechanical performance	1748:1773	the mechanical performance	1748:1773	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	13	25	theme	liquid	1834:1839	arg1	state					1841:1845	liquid state	1834:1845	liquid state	1834:1845	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	3	26	theme	good	470:473	arg1	properties					486:495	very good mechanical properties	465:495	very good mechanical properties	465:495	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	0	27	theme	layered	17:23	arg1	composite					54:62	a layered bacterial nanocellulose-PHBV composite	15:62	a layered bacterial nanocellulose-PHBV composite for food packaging	15:81	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.					
35218225	12	28	theme	composite	1585:1593	arg1	properties					1559:1568	the mechanical and barrier properties	1532:1568	properties	1559:1568	CONCLUSIONS Overall, the mechanical and barrier properties of the layered composite obtained were considered suitable for food-packaging applications.					
35218225	13	29	with	plasticizing	1666:1677	arg1	glycerol					1685:1692	glycerol	1685:1692	glycerol	1685:1692	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	13	29	with	plasticizing	1666:1677	arg1	glycol					1710:1715	polyethylene glycol	1697:1715	polyethylene glycol	1697:1715	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	8	30	theme	Overall	1207:1213	arg1	RESULTS					1199:1205	148 °C. RESULTS Overall	1191:1213	148 °C. RESULTS Overall	1191:1213	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	8	30	theme	Overall	1207:1213	arg1	PHBV					1216:1219	PHBV	1216:1219	PHBV coating on plasticized BNC	1216:1246	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	4	31	theme	food-packaging	607:620	arg1	applications					622:633	food-packaging applications	607:633	food-packaging applications	607:633	However, its water-vapor permeability is too high for food-packaging applications.					
35218225	10	32	theme	50	1346:1347	arg1	%					1348:1348	%	1348:1348	%	1348:1348	Pa-1 ) under 50% relative humidity.					
35218225	1	33	theme	current	107:113	arg1	materials					115:123	the current materials	103:123	the current materials used in food packaging	103:146	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	14	34	theme	Chemical	1874:1881	arg1	Industry					1883:1890	Chemical Industry	1874:1890	Chemical Industry	1874:1890	© 2022 Society of Chemical Industry.					
35218225	0	35	theme	nanocellulose-PHBV	35:52	arg1	composite					54:62	a layered bacterial nanocellulose-PHBV composite	15:62	a layered bacterial nanocellulose-PHBV composite for food packaging	15:81	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.					
35218225	13	36	dep	affinity	1814:1821	arg1	vapor					1824:1828	vapor	1824:1828	vapor	1824:1828	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	13	36	dep	affinity	1814:1821	arg1	state					1841:1845	liquid state	1834:1845	liquid state	1834:1845	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	1	37	theme	environmental	190:202	arg1	issues					204:209	environmental issues	190:209	environmental issues derived from the accumulation of plastics in landfills/waterways	190:274	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	0	38	theme	bacterial	25:33	arg1	composite					54:62	a layered bacterial nanocellulose-PHBV composite	15:62	a layered bacterial nanocellulose-PHBV composite for food packaging	15:81	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.					
35218225	4	39	theme	water-vapor	566:576	arg1	permeability					578:589	its water-vapor permeability	562:589	its water-vapor permeability	562:589	However, its water-vapor permeability is too high for food-packaging applications.					
35218225	6	40	with	biopolymer	823:832	arg1	degree					844:849	high degree	839:849	high degree of hydrophobicity and biodegradability	839:888	Polyhydroxyalkanoate is a biopolymer with high degree of hydrophobicity and biodegradability, and is also obtained by fermentation.					
35218225	12	41	theme	barrier	1551:1557	arg1	properties					1559:1568	the mechanical and barrier properties	1532:1568	properties	1559:1568	CONCLUSIONS Overall, the mechanical and barrier properties of the layered composite obtained were considered suitable for food-packaging applications.					
35218225	10	42	theme	relative	1350:1357	arg1	humidity					1359:1366	50% relative humidity	1346:1366	50% relative humidity	1346:1366	Pa-1 ) under 50% relative humidity.					
35218225	10	43	dep	Pa-1	1333:1336	arg1	humidity					1359:1366	50% relative humidity	1346:1366	50% relative humidity	1346:1366	Pa-1 ) under 50% relative humidity.					
35218225	8	44	theme	plasticized	1232:1242	arg1	BNC					1244:1246	plasticized BNC	1232:1246	plasticized BNC	1232:1246	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	8	45	theme	PHBV	1133:1136	arg1	solution					1138:1145	PHBV solution	1133:1145	PHBV solution dissolved in formic acid	1133:1170	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	3	46	theme	Bacterial	388:396	arg1	biopolymer					421:430	a biopolymer	419:430	a biopolymer obtained by fermentation	419:455	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	3	46	theme	Bacterial	388:396	arg1	BNC					413:415	BNC	413:415	BNC	413:415	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	3	46	theme	Bacterial	388:396	arg1	nanocellulose					398:410	Bacterial nanocellulose	388:410	Bacterial nanocellulose (BNC)	388:416	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	10	47	theme	%	1348:1348	arg1	humidity					1359:1366	50% relative humidity	1346:1366	50% relative humidity	1346:1366	Pa-1 ) under 50% relative humidity.					
35218225	1	48	theme	materials	115:123	arg1	BACKGROUND					84:93	BACKGROUND Most	84:98	BACKGROUND Most of the current materials used in food packaging	84:146	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	0	49	theme	composite	54:62	arg1	Development					0:10	Development	0:10	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.	0:82	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.					
35218225	12	50	theme	layered	1577:1583	arg1	composite					1585:1593	the layered composite	1573:1593	the layered composite obtained	1573:1602	CONCLUSIONS Overall, the mechanical and barrier properties of the layered composite obtained were considered suitable for food-packaging applications.					
35218225	1	51	attach	derived	211:217	arg1	accumulation					228:239	the accumulation	224:239	the accumulation of plastics in landfills/waterways	224:274	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	1	51	attach	derived	211:217	arg2	issues					204:209	environmental issues	190:209	environmental issues derived from the accumulation of plastics in landfills/waterways	190:274	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	7	52	theme	polyethylene	1052:1063	arg1	glycol					1065:1070	polyethylene glycol	1052:1070	polyethylene glycol (MW 600) (BNCPEG )	1052:1089	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	7	52	theme	polyethylene	1052:1063	arg1	BNCPEG					1082:1087	BNCPEG	1082:1087	BNCPEG	1082:1087	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	7	52	theme	polyethylene	1052:1063	arg1	MW					1073:1074	MW 600	1073:1078	MW 600	1073:1078	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	3	53	theme	active	534:539	arg1	substances					541:550	active substances	534:550	active substances	534:550	Bacterial nanocellulose (BNC), a biopolymer obtained by fermentation, offers very good mechanical properties and the ability to carry and deliver active substances.					
35218225	1	54	from	accumulation	228:239	arg1	landfills/waterways					256:274	landfills/waterways	256:274	landfills/waterways	256:274	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	11	55	from	80-90°	1431:1436	arg1	angle					1410:1414	contact angle	1402:1414	contact angle from 10-40° to 80-90°	1402:1436	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35218225	2	56	theme	food	281:284	arg1	industry					286:293	The food industry	277:293	The food industry	277:293	The food industry increasingly needs eco-friendly sustainable materials that meet food-packaging requirements.					
35218225	7	57	theme	glycerol	1030:1037	arg1	solutions					1010:1018	solutions	1010:1018	solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG )	1010:1089	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	12	58	theme	mechanical	1536:1545	arg1	properties					1559:1568	the mechanical and barrier properties	1532:1568	properties	1559:1568	CONCLUSIONS Overall, the mechanical and barrier properties of the layered composite obtained were considered suitable for food-packaging applications.					
35218225	7	59	theme	glycol	1065:1070	arg1	solutions					1010:1018	solutions	1010:1018	solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG )	1010:1089	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	8	60	dep	0.032 g.μm.m-2	1310:1323	arg1	0.990					1301:1305	0.990	1301:1305	0.990	1301:1305	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	12	61	theme	food-packaging	1633:1646	arg1	applications					1648:1659	food-packaging applications	1633:1659	food-packaging applications	1633:1659	CONCLUSIONS Overall, the mechanical and barrier properties of the layered composite obtained were considered suitable for food-packaging applications.					
35218225	2	62	theme	food-packaging	359:372	arg1	requirements					374:385	food-packaging requirements	359:385	food-packaging requirements	359:385	The food industry increasingly needs eco-friendly sustainable materials that meet food-packaging requirements.					
35218225	8	63	theme	formic	1160:1165	arg1	acid					1167:1170	formic acid	1160:1170	formic acid	1160:1170	The plasticized BNC was then coated with PHBV solution dissolved in formic acid, and oven dried at 148 °C. RESULTS Overall, PHBV coating on plasticized BNC reduced water vapor permeability significantly (from 0.990 to 0.032 g.μm.m-2 .					
35218225	7	64	theme	BNC	933:935	arg1	membranes					937:945	Wet BNC membranes	929:945	Wet BNC membranes produced by static culture	929:972	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	7	65	theme	static	959:964	arg1	culture					966:972	static culture	959:972	static culture	959:972	Wet BNC membranes produced by static culture were plasticized by impregnation of solutions of either glycerol (BNCgly ) or polyethylene glycol (MW 600) (BNCPEG ).					
35218225	1	66	theme	plastics	244:251	arg1	accumulation					228:239	the accumulation	224:239	the accumulation of plastics in landfills/waterways	224:274	BACKGROUND Most of the current materials used in food packaging are synthetic and non-degradable, raising environmental issues derived from the accumulation of plastics in landfills/waterways.					
35218225	0	67	theme	food	68:71	arg1	packaging					73:81	food packaging	68:81	food packaging	68:81	Development of a layered bacterial nanocellulose-PHBV composite for food packaging.					
35218225	13	68	theme	PHBV	1783:1786	arg1	coating					1788:1794	the PHBV coating	1779:1794	the PHBV coating	1779:1794	The plasticizing (with glycerol or polyethylene glycol) of BNC significantly improved the mechanical performance and the PHBV coating reduced the water affinity (vapor and liquid state) on BNC.					
35218225	11	69	dep	80-90°	1431:1436	arg1	to					1428:1429	to	1428:1429	to	1428:1429	It increased the hydrophobicity (contact angle from 10-40° to 80-90°) but decreased the stiffness (from 3.1 GPa to 1.3 Gpa) of the composite.					
35100806	6	0	from	articles	849:856	arg1	RESULTS					831:837	RESULTS	831:837	RESULTS From 1308 articles identified, 10	831:871	RESULTS From 1308 articles identified, 10 were selected.					
35100806	10	1	theme	FODMAP	1299:1304	arg1	diet					1306:1309	the FODMAP diet	1295:1309	the FODMAP diet	1295:1309	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	1	2	theme	monosaccharides	159:173	arg1	BACKGROUND					73:82	BACKGROUND	73:82	BACKGROUND	73:82	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	1	2	theme	monosaccharides	159:173	arg1	intake					100:105	AIM Reduced intake	88:105	AIM Reduced intake	88:105	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	10	3	theme	foods	1209:1213	arg1	lists					1189:1193	CONCLUSION Unvarying lists	1168:1193	CONCLUSION Unvarying lists of low-FODMAP foods	1168:1213	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	4	4	theme	FODMAP	545:550	arg1	lists					536:540	the lists	532:540	the lists of FODMAP	532:550	We hypothesized the lists of FODMAP do not comprise all products that can contain high levels of FODMAP.					
35100806	6	5	theme	10	870:871	arg1	articles					849:856	1308 articles	844:856	1308 articles identified	844:867	RESULTS From 1308 articles identified, 10 were selected.					
35100806	7	6	theme	foods	905:909	arg1	%					892:892	22.6%	888:892	22.6% of the 204 foods listed	888:916	22.6% of the 204 foods listed were classified differently between studies.					
35100806	7	6	theme	foods	905:909	arg1	foods					905:909	the 204 foods	897:909	the 204 foods listed	897:916	22.6% of the 204 foods listed were classified differently between studies.					
35100806	2	7	theme	FODMAP	334:339	arg1	list					326:329	the list	322:329	the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods	322:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	10	8	theme	low-FODMAP	1198:1207	arg1	foods					1209:1213	low-FODMAP foods	1198:1213	low-FODMAP foods	1198:1213	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	3	9	theme	FODMAP	471:476	arg1	lists					478:482	the FODMAP lists	467:482	the FODMAP lists	467:482	This study aimed to emphasize the need to unify the FODMAP lists to prevent patients' confusion.					
35100806	5	10	theme	FODMAP	817:822	arg1	lists					824:828	FODMAP lists	817:828	FODMAP lists	817:828	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	2	11	theme	FODMAP-profiles	361:375	arg1	characterization					377:392	FODMAP-profiles characterization	361:392	FODMAP-profiles characterization of many different foods	361:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	5	12	theme	food	698:701	arg1	tables					715:720	food composition tables	698:720	food composition tables	698:720	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg2	lists					824:828	FODMAP lists	817:828	FODMAP lists	817:828	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg1	publications					748:759	food analytical publications	732:759	food analytical publications	732:759	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg1	trials					795:800	clinical trials	786:800	clinical trials	786:800	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg1	tables					715:720	food composition tables	698:720	food composition tables	698:720	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg1	reviews					723:729	reviews	723:729	reviews	723:729	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	13	contain	contained	807:815	arg1	analysis					773:780	laboratory analysis	762:780	laboratory analysis	762:780	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	14	dep	METHODS	621:627	arg1	PubMed					629:634	PubMed	629:634	PubMed	629:634	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	14	dep	METHODS	621:627	arg1	Cochrane					663:670	Cochrane	663:670	Cochrane	663:670	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	14	dep	METHODS	621:627	arg1	Scielo					652:657	Scielo	652:657	Scielo	652:657	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	5	14	dep	METHODS	621:627	arg1	METHODS					621:627	METHODS	621:627	METHODS PubMed, ScienceDirect, Scielo and Cochrane	621:670	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	10	15	from	information	1280:1290	arg1	diet					1306:1309	the FODMAP diet	1295:1309	the FODMAP diet	1295:1309	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	5	16	theme	laboratory	762:771	arg1	analysis					773:780	laboratory analysis	762:780	laboratory analysis	762:780	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	10	17	with	patient	1258:1264	arg1	information					1280:1290	accurate information	1271:1290	accurate information on the FODMAP diet	1271:1309	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	1	18	theme	Reduced	92:98	arg1	intake					100:105	AIM Reduced intake	88:105	AIM Reduced intake	88:105	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	0	19	theme	available	29:37	arg1	lists					39:43	available lists	29:43	available lists of FODMAP containing foods	29:70	Existing differences between available lists of FODMAP containing foods.					
35100806	5	20	theme	analytical	737:746	arg1	publications					748:759	food analytical publications	732:759	food analytical publications	732:759	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	2	21	theme	different	402:410	arg1	foods					412:416	many different foods	397:416	many different foods	397:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	2	22	theme	foods	412:416	arg1	characterization					377:392	FODMAP-profiles characterization	361:392	FODMAP-profiles characterization of many different foods	361:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	8	23	theme	soft	1014:1017	arg1	cheese					1019:1024	soft cheese	1014:1024	soft cheese	1014:1024	This included almonds, avocados, banana, broccoli, soft cheese, eggplant and walnuts.					
35100806	1	24	dep	Reduced	92:98	arg1	AIM					88:90	AIM	88:90	AIM	88:90	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	2	25	theme	many	397:400	arg1	foods					412:416	many different foods	397:416	many different foods	397:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	9	26	theme	Nutritional	1049:1059	arg1	guidance					1061:1068	Nutritional guidance	1049:1068	Nutritional guidance	1049:1068	Nutritional guidance can be taken from existing FODMAP-literature, but the information given is not always consistent.					
35100806	4	27	theme	FODMAP	613:618	arg1	levels					603:608	high levels	598:608	high levels of FODMAP	598:618	We hypothesized the lists of FODMAP do not comprise all products that can contain high levels of FODMAP.					
35100806	5	28	theme	food	732:735	arg1	publications					748:759	food analytical publications	732:759	food analytical publications	732:759	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	2	29	theme	characterization	377:392	arg1	lack					353:356	the lack	349:356	the lack of FODMAP-profiles characterization of many different foods	349:416	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35100806	0	30	theme	containing	55:64	arg1	foods					66:70	FODMAP containing foods	48:70	FODMAP containing foods	48:70	Existing differences between available lists of FODMAP containing foods.					
35100806	4	31	contain	contain	590:596	arg2	levels					603:608	high levels	598:608	high levels of FODMAP	598:618	We hypothesized the lists of FODMAP do not comprise all products that can contain high levels of FODMAP.					
35100806	4	31	contain	contain	590:596	arg1	products					572:579	all products	568:579	all products that can contain high levels of FODMAP	568:618	We hypothesized the lists of FODMAP do not comprise all products that can contain high levels of FODMAP.					
35100806	1	32	theme	fermentable	110:120	arg1	oligosaccharides					122:137	fermentable oligosaccharides	110:137	fermentable oligosaccharides	110:137	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	0	33	theme	FODMAP	48:53	arg1	foods					66:70	FODMAP containing foods	48:70	FODMAP containing foods	48:70	Existing differences between available lists of FODMAP containing foods.					
35100806	1	34	theme	oligosaccharides	122:137	arg1	BACKGROUND					73:82	BACKGROUND	73:82	BACKGROUND	73:82	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	1	34	theme	oligosaccharides	122:137	arg1	intake					100:105	AIM Reduced intake	88:105	AIM Reduced intake	88:105	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	10	35	theme	accurate	1271:1278	arg1	information					1280:1290	accurate information	1271:1290	accurate information on the FODMAP diet	1271:1309	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	10	36	theme	Unvarying	1179:1187	arg1	lists					1189:1193	CONCLUSION Unvarying lists	1168:1193	CONCLUSION Unvarying lists of low-FODMAP foods	1168:1213	CONCLUSION Unvarying lists of low-FODMAP foods should be elaborated that will provide the patient with accurate information on the FODMAP diet.					
35100806	1	37	theme	functional	215:224	arg1	disorders					243:251	functional gastrointestinal disorders	215:251	functional gastrointestinal disorders	215:251	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	1	38	theme	disaccharides	140:152	arg1	BACKGROUND					73:82	BACKGROUND	73:82	BACKGROUND	73:82	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	1	38	theme	disaccharides	140:152	arg1	intake					100:105	AIM Reduced intake	88:105	AIM Reduced intake	88:105	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	1	39	theme	gastrointestinal	226:241	arg1	disorders					243:251	functional gastrointestinal disorders	215:251	functional gastrointestinal disorders	215:251	BACKGROUND AND AIM Reduced intake of fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) is useful to treat functional gastrointestinal disorders.					
35100806	5	40	theme	composition	703:713	arg1	tables					715:720	food composition tables	698:720	food composition tables	698:720	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	4	41	theme	high	598:601	arg1	levels					603:608	high levels	598:608	high levels of FODMAP	598:618	We hypothesized the lists of FODMAP do not comprise all products that can contain high levels of FODMAP.					
35100806	5	42	theme	clinical	786:793	arg1	trials					795:800	clinical trials	786:800	clinical trials	786:800	METHODS PubMed, ScienceDirect, Scielo and Cochrane were searched to identify food composition tables, reviews, food analytical publications, laboratory analysis and clinical trials that contained FODMAP lists.					
35100806	0	43	theme	foods	66:70	arg1	lists					39:43	available lists	29:43	available lists of FODMAP containing foods	29:70	Existing differences between available lists of FODMAP containing foods.					
35100806	2	44	theme	due	342:344	arg1	FODMAP					334:339	FODMAP	334:339	FODMAP	334:339	However, there is no consensus on which foods should be included in the list of FODMAP, due to the lack of FODMAP-profiles characterization of many different foods.					
35642970	4	0	theme	reduced	875:881	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	0	theme	reduced	875:881	arg1	factors					896:902	reduced inflammatory factors	875:902	reduced inflammatory factors	875:902	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	1	theme	chronic	496:502	arg1	deprivation					510:520	chronic sleep deprivation	496:520	chronic sleep deprivation	496:520	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	5	2	theme	intestinal	1188:1197	arg1	flora					1199:1203	the intestinal flora	1184:1203	the intestinal flora of rats with anxiety	1184:1224	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	11	3	theme	microflora	2477:2486	arg1	imbalance					2488:2496	the gut microflora imbalance	2469:2496	the gut microflora imbalance	2469:2496	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	3	4	theme	-induced	527:534	arg1	anxiety					536:542	chronic sleep deprivation (CSD)-induced anxiety	496:542	chronic sleep deprivation (CSD)-induced anxiety in rats	496:550	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	11	5	theme	PCWP	2324:2327	arg1	effect					2314:2319	the potential effect	2300:2319	the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance	2300:2496	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	4	6	theme	gastrointestinal	842:857	arg1	levels					867:872	regulated gastrointestinal peptide levels	832:872	regulated gastrointestinal peptide levels	832:872	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	6	theme	gastrointestinal	842:857	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	9	7	theme	taurine	2005:2011	arg1	results					2056:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	4	8	theme	neurotransmitter	629:644	arg1	levels					646:651	reduced neurotransmitter levels	621:651	reduced neurotransmitter levels	621:651	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	8	9	theme	metabolomics	1793:1804	arg1	results					1776:1782	The results	1772:1782	The results of serum metabolomics	1772:1804	The results of serum metabolomics showed that 26 biomarkers were significantly changed after PCWP intervention compared with the model group.					
35642970	10	10	theme	potential	2223:2231	arg1	biomarkers					2233:2242	potential biomarkers	2223:2242	potential biomarkers	2223:2242	A strong correlation between intestinal bacteria and potential biomarkers was found.					
35642970	1	11	theme	P.	203:204	arg1	cocos					196:200	Poria cocos	190:200	Poria cocos (P. cocos)	190:211	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	11	theme	P.	203:204	arg1	cocos					206:210	P. cocos	203:210	P. cocos	203:210	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	4	12	theme	necrosis	929:936	arg1	TNF					946:948	TNF	946:948	TNF	946:948	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	12	theme	necrosis	929:936	arg1	factor					938:943	the tumor necrosis factor	919:943	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	1	13	from	food	273:276	arg1	China					281:285	China	281:285	China	281:285	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	5	14	theme	flora	1042:1046	arg1	composition					1048:1058	the intestinal flora composition	1027:1058	the intestinal flora composition	1027:1058	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	6	15	theme	PCWP-treated	1543:1554	arg1	groups					1556:1561	the PCWP-treated groups	1539:1561	the PCWP-treated groups	1539:1561	Metabolomics was used to analyze fecal samples to identify significantly altered metabolites in the PCWP-treated groups.					
35642970	7	16	theme	vitamin	1699:1705	arg1	metabolism					1710:1719	vitamin B6 metabolism	1699:1719	vitamin B6 metabolism	1699:1719	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	10	17	theme	intestinal	2199:2208	arg1	bacteria					2210:2217	intestinal bacteria	2199:2217	intestinal bacteria	2199:2217	A strong correlation between intestinal bacteria and potential biomarkers was found.					
35642970	9	18	theme	validation	2045:2054	arg1	results					2056:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	0	19	theme	TNF-α/NF-κB	159:169	arg1	pathway					181:187	TNF-α/NF-κB signaling pathway	159:187	TNF-α/NF-κB signaling pathway	159:187	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	9	20	theme	PCWP	2076:2079	arg1	intervention					2081:2092	PCWP intervention	2076:2092	PCWP intervention	2076:2092	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	4	21	from	acid	806:809	arg1	hypothalamus					818:829	the hypothalamus	814:829	the hypothalamus	814:829	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	22	dep	-induced	527:534	arg1	deprivation					510:520	chronic sleep deprivation	496:520	chronic sleep deprivation	496:520	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	4	23	theme	NF	969:970	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	24	theme	PCWP	662:665	arg1	intervention					667:678	PCWP intervention	662:678	PCWP intervention	662:678	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	5	25	theme	dysregulated	1271:1282	arg1	bacteria					1284:1291	the following dysregulated bacteria	1257:1291	the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter	1257:1440	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	11	26	theme	anxiety	2362:2368	arg1	progression					2347:2357	the progression	2343:2357	the progression of anxiety	2343:2368	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	7	27	theme	sphingolipid	1638:1649	arg1	metabolism					1651:1660	sphingolipid metabolism	1638:1660	sphingolipid metabolism	1638:1660	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	4	28	theme	-κB	972:974	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	29	from	norepinephrine	771:784	arg1	hypothalamus					818:829	the hypothalamus	814:829	the hypothalamus	814:829	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	9	30	theme	enzymes	2120:2126	arg1	activity					2108:2115	the activity	2104:2115	the activity of enzymes involved in the above metabolic pathways	2104:2167	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	4	31	from	dopamine	761:768	arg1	hypothalamus					818:829	the hypothalamus	814:829	the hypothalamus	814:829	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	7	32	theme	metabolic	1611:1619	arg1	pathways					1621:1628	four metabolic pathways	1606:1628	four metabolic pathways	1606:1628	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	32	theme	metabolic	1611:1619	arg1	metabolism					1687:1696	taurine and hypotaurine metabolism	1663:1696	metabolism	1687:1696	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	32	theme	metabolic	1611:1619	arg1	metabolism					1651:1660	sphingolipid metabolism	1638:1660	sphingolipid metabolism	1638:1660	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	32	theme	metabolic	1611:1619	arg1	metabolism					1746:1755	glycerophospholipid metabolism	1726:1755	glycerophospholipid metabolism	1726:1755	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	32	theme	metabolic	1611:1619	arg1	metabolism					1710:1719	vitamin B6 metabolism	1699:1719	vitamin B6 metabolism	1699:1719	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	4	33	theme	factor	961:966	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	34	theme	water-soluble	425:437	arg1	polysaccharide					439:452	the water-soluble polysaccharide	421:452	the water-soluble polysaccharide from P. cocos (PCWP)	421:473	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	0	35	theme	gut	120:122	arg1	dysbiosis					124:132	the gut dysbiosis	116:132	the gut dysbiosis	116:132	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	5	36	theme	rDNA	1086:1089	arg1	sequencing					1091:1100	16S rDNA sequencing	1082:1100	16S rDNA sequencing	1082:1100	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	9	37	theme	above	2144:2148	arg1	pathways					2160:2167	the above metabolic pathways	2140:2167	the above metabolic pathways	2140:2167	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	2	38	theme	cocos	374:378	arg1	decoction					380:388	P. cocos decoction	371:388	P. cocos decoction	371:388	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	0	39	theme	Poria	0:4	arg1	polysaccharide					26:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	4	40	from	levels	730:735	arg1	hypothalamus					818:829	the hypothalamus	814:829	the hypothalamus	814:829	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	7	41	theme	glycerophospholipid	1726:1744	arg1	metabolism					1746:1755	glycerophospholipid metabolism	1726:1755	glycerophospholipid metabolism	1726:1755	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	11	42	theme	new	2276:2278	arg1	evidence					2280:2287	new evidence	2276:2287	new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance	2276:2496	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	acid					806:809	γ-aminobutyric acid	791:809	γ-aminobutyric acid	791:809	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	dopamine					761:768	dopamine	761:768	dopamine	761:768	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	levels					867:872	regulated gastrointestinal peptide levels	832:872	regulated gastrointestinal peptide levels	832:872	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	norepinephrine					771:784	norepinephrine	771:784	norepinephrine	771:784	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	43	theme	5-hydroxytryptamine	740:758	arg1	factors					896:902	reduced inflammatory factors	875:902	reduced inflammatory factors	875:902	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	5	44	theme	closer	1293:1298	arg1	bacteria					1284:1291	the following dysregulated bacteria	1257:1291	the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter	1257:1440	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	0	45	theme	water-soluble	12:24	arg1	polysaccharide					26:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	9	46	theme	regulatory	1918:1927	arg1	effects					1929:1935	The regulatory effects	1914:1935	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1914:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	7	47	theme	Thirty-eight	1564:1575	arg1	metabolism					1651:1660	sphingolipid metabolism	1638:1660	sphingolipid metabolism	1638:1660	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	47	theme	Thirty-eight	1564:1575	arg1	metabolism					1687:1696	taurine and hypotaurine metabolism	1663:1696	metabolism	1687:1696	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	47	theme	Thirty-eight	1564:1575	arg1	metabolites					1590:1600	Thirty-eight PCWP-related metabolites	1564:1600	Thirty-eight PCWP-related metabolites	1564:1600	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	47	theme	Thirty-eight	1564:1575	arg1	metabolism					1746:1755	glycerophospholipid metabolism	1726:1755	glycerophospholipid metabolism	1726:1755	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	47	theme	Thirty-eight	1564:1575	arg1	metabolism					1710:1719	vitamin B6 metabolism	1699:1719	vitamin B6 metabolism	1699:1719	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	11	48	theme	potential	2304:2312	arg1	effect					2314:2319	the potential effect	2300:2319	the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance	2300:2496	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	4	49	from	pathway	986:992	arg1	rats					997:1000	rats	997:1000	rats with CSD	997:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	9	50	theme	metabolic	1940:1948	arg1	enrichment					1958:1967	metabolic pathway enrichment	1940:1967	metabolic pathway enrichment	1940:1967	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	2	51	theme	water-soluble	317:329	arg1	polysaccharide					331:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	2	51	theme	water-soluble	317:329	arg1	component					358:366	the main component	349:366	the main component of P. cocos decoction	349:388	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	5	52	theme	rats	1208:1211	arg1	flora					1199:1203	the intestinal flora	1184:1203	the intestinal flora of rats with anxiety	1184:1224	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	1	53	used	used	236:239	arg2	food					273:276	functional food	262:276	functional food	262:276	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	53	used	used	236:239	arg2	cocos					206:210	P. cocos	203:210	P. cocos	203:210	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	53	used	used	236:239	arg2	cocos					196:200	Poria cocos	190:200	Poria cocos (P. cocos)	190:211	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	53	used	used	236:239	arg2	medicine					249:256	folk medicine	244:256	folk medicine	244:256	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	9	54	theme	enrichment	1958:1967	arg1	effects					1929:1935	The regulatory effects	1914:1935	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1914:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	4	55	theme	gut	574:576	arg1	dysbiosis					578:586	gut dysbiosis	574:586	gut dysbiosis	574:586	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	56	theme	sleep	504:508	arg1	deprivation					510:520	chronic sleep deprivation	496:520	chronic sleep deprivation	496:520	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	9	57	from	effects	1929:1935	arg1	results					2056:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	5	58	dep	bacteria	1284:1291	arg1	Ruminococcus					1358:1369	Ruminococcus	1358:1369	Ruminococcus	1358:1369	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	5	58	dep	bacteria	1284:1291	arg1	Rikenellaceae_RC9_gut_group					1329:1355	Rikenellaceae_RC9_gut_group	1329:1355	Rikenellaceae_RC9_gut_group	1329:1355	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	5	58	dep	bacteria	1284:1291	arg1	Fusicatenibacter					1425:1440	Fusicatenibacter	1425:1440	Fusicatenibacter	1425:1440	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	9	59	theme	sphingolipid	1972:1983	arg1	results					2056:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	2	60	theme	main	353:356	arg1	polysaccharide					331:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	2	60	theme	main	353:356	arg1	component					358:366	the main component	349:366	the main component of P. cocos decoction	349:388	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	9	61	theme	phenylalanine	1986:1998	arg1	results					2056:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results	1972:2062	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	6	62	theme	fecal	1476:1480	arg1	samples					1482:1488	fecal samples	1476:1488	fecal samples	1476:1488	Metabolomics was used to analyze fecal samples to identify significantly altered metabolites in the PCWP-treated groups.					
35642970	1	63	theme	functional	262:271	arg1	cocos					196:200	Poria cocos	190:200	Poria cocos (P. cocos)	190:211	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	63	theme	functional	262:271	arg1	food					273:276	functional food	262:276	functional food	262:276	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	4	64	theme	inflammatory	883:894	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	64	theme	inflammatory	883:894	arg1	factors					896:902	reduced inflammatory factors	875:902	reduced inflammatory factors	875:902	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	11	65	theme	signaling	2400:2408	arg1	pathway					2410:2416	the TNF-α/NF-κB signaling pathway	2384:2416	the TNF-α/NF-κB signaling pathway	2384:2416	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	11	66	theme	TNF-α/NF-κB	2388:2398	arg1	pathway					2410:2416	the TNF-α/NF-κB signaling pathway	2384:2416	the TNF-α/NF-κB signaling pathway	2384:2416	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	1	67	theme	Poria	190:194	arg1	medicine					249:256	folk medicine	244:256	folk medicine	244:256	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	67	theme	Poria	190:194	arg1	cocos					196:200	Poria cocos	190:200	Poria cocos (P. cocos)	190:211	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	67	theme	Poria	190:194	arg1	cocos					206:210	P. cocos	203:210	P. cocos	203:210	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	67	theme	Poria	190:194	arg1	food					273:276	functional food	262:276	functional food	262:276	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	4	68	theme	regulated	832:840	arg1	levels					867:872	regulated gastrointestinal peptide levels	832:872	regulated gastrointestinal peptide levels	832:872	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	68	theme	regulated	832:840	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	69	with	rats	997:1000	arg1	CSD					1007:1009	CSD	1007:1009	CSD	1007:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	70	theme	reduced	621:627	arg1	levels					646:651	reduced neurotransmitter levels	621:651	reduced neurotransmitter levels	621:651	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	8	71	theme	serum	1787:1791	arg1	metabolomics					1793:1804	serum metabolomics	1787:1804	serum metabolomics	1787:1804	The results of serum metabolomics showed that 26 biomarkers were significantly changed after PCWP intervention compared with the model group.					
35642970	7	72	theme	B6	1707:1708	arg1	metabolism					1710:1719	vitamin B6 metabolism	1699:1719	vitamin B6 metabolism	1699:1719	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	4	73	theme	peptide	859:865	arg1	levels					867:872	regulated gastrointestinal peptide levels	832:872	regulated gastrointestinal peptide levels	832:872	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	73	theme	peptide	859:865	arg1	levels					730:735	the levels	726:735	the levels of 5-hydroxytryptamine	726:758	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	11	74	theme	metabolic	2431:2439	arg1	disorders					2441:2449	metabolic disorders	2431:2449	metabolic disorders	2431:2449	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	0	75	theme	metabolic	135:143	arg1	disorders					145:153	metabolic disorders	135:153	metabolic disorders	135:153	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	8	76	theme	model	1901:1905	arg1	group					1907:1911	the model group	1897:1911	the model group	1897:1911	The results of serum metabolomics showed that 26 biomarkers were significantly changed after PCWP intervention compared with the model group.					
35642970	4	77	theme	tumor	923:927	arg1	TNF					946:948	TNF	946:948	TNF	946:948	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	77	theme	tumor	923:927	arg1	factor					938:943	the tumor necrosis factor	919:943	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	4	78	theme	inflammatory	593:604	arg1	responses					606:614	inflammatory responses	593:614	inflammatory responses	593:614	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	1	79	from	medicine	249:256	arg1	China					281:285	China	281:285	China	281:285	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	7	80	theme	hypotaurine	1675:1685	arg1	metabolism					1687:1696	taurine and hypotaurine metabolism	1663:1696	metabolism	1687:1696	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	4	81	theme	factor	938:943	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	0	82	theme	signaling	171:179	arg1	pathway					181:187	TNF-α/NF-κB signaling pathway	159:187	TNF-α/NF-κB signaling pathway	159:187	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	7	83	theme	taurine	1663:1669	arg1	metabolism					1687:1696	taurine and hypotaurine metabolism	1663:1696	metabolism	1687:1696	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	4	84	theme	anxiety-like	692:703	arg1	behaviors					705:713	anxiety-like behaviors	692:713	anxiety-like behaviors	692:713	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	85	from	anxiety	536:542	arg1	rats					547:550	rats	547:550	rats	547:550	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	9	86	dep	taurine	2005:2011	arg1	metabolism					2029:2038	metabolism	2029:2038	metabolism	2029:2038	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	5	87	theme	following	1261:1269	arg1	bacteria					1284:1291	the following dysregulated bacteria	1257:1291	the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter	1257:1440	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	0	88	theme	sleep	84:88	arg1	deprivation					90:100	sleep deprivation	84:100	sleep deprivation	84:100	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	5	89	theme	intestinal	1031:1040	arg1	flora					1042:1046	the intestinal flora	1027:1046	the intestinal flora composition	1027:1058	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	8	90	theme	PCWP	1865:1868	arg1	intervention					1870:1881	PCWP intervention	1865:1881	PCWP intervention	1865:1881	The results of serum metabolomics showed that 26 biomarkers were significantly changed after PCWP intervention compared with the model group.					
35642970	10	91	theme	strong	2172:2177	arg1	correlation					2179:2189	A strong correlation	2170:2189	A strong correlation between intestinal bacteria and potential biomarkers	2170:2242	A strong correlation between intestinal bacteria and potential biomarkers was found.					
35642970	5	92	from	changes	1016:1022	arg1	composition					1048:1058	the intestinal flora composition	1027:1058	the intestinal flora composition	1027:1058	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	3	93	from	effects	395:401	arg1	PCWP					469:472	PCWP	469:472	PCWP	469:472	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	93	from	effects	395:401	arg1	cocos					462:466	P. cocos	459:466	P. cocos (PCWP)	459:473	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	11	94	theme	gut	2473:2475	arg1	microflora					2477:2486	the gut microflora	2469:2486	the gut microflora imbalance	2469:2496	Our findings present new evidence supporting the potential effect of PCWP in preventing the progression of anxiety by inhibiting the TNF-α/NF-κB signaling pathway, alleviating metabolic disorders, and ameliorating the gut microflora imbalance.					
35642970	3	95	from	mechanisms	407:416	arg1	PCWP					469:472	PCWP	469:472	PCWP	469:472	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	95	from	mechanisms	407:416	arg1	cocos					462:466	P. cocos	459:466	P. cocos (PCWP)	459:473	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	5	96	theme	16S	1082:1084	arg1	sequencing					1091:1100	16S rDNA sequencing	1082:1100	16S rDNA sequencing	1082:1100	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	4	97	theme	-α/nuclear	950:959	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	98	dep	effects	395:401	arg1	The					391:393	The	391:393	The	391:393	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	5	99	theme	normal	1315:1320	arg1	group					1322:1326	the normal group	1311:1326	the normal group	1311:1326	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	2	100	theme	decoction	380:388	arg1	polysaccharide					331:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide	313:344	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	2	100	theme	decoction	380:388	arg1	component					358:366	the main component	349:366	the main component of P. cocos decoction	349:388	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	0	101	theme	cocos	6:10	arg1	polysaccharide					26:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide	0:39	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	9	102	theme	metabolic	2150:2158	arg1	pathways					2160:2167	the above metabolic pathways	2140:2167	the above metabolic pathways	2140:2167	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	5	103	theme	bacteria	1284:1291	arg1	abundance					1244:1252	the abundance	1240:1252	the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter	1240:1440	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	2	104	theme	P.	371:372	arg1	decoction					380:388	P. cocos decoction	371:388	P. cocos decoction	371:388	The water-soluble polysaccharide is the main component of P. cocos decoction.					
35642970	0	105	theme	anxiety-like	51:62	arg1	behavior					64:71	anxiety-like behavior	51:71	anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway	51:187	Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.					
35642970	4	106	theme	signaling	976:984	arg1	pathway					986:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway	919:992	the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD	919:1009	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	3	107	theme	P.	459:460	arg1	PCWP					469:472	PCWP	469:472	PCWP	469:472	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	107	theme	P.	459:460	arg1	cocos					462:466	P. cocos	459:466	P. cocos (PCWP)	459:473	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	7	108	theme	PCWP-related	1577:1588	arg1	metabolism					1651:1660	sphingolipid metabolism	1638:1660	sphingolipid metabolism	1638:1660	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	108	theme	PCWP-related	1577:1588	arg1	metabolism					1687:1696	taurine and hypotaurine metabolism	1663:1696	metabolism	1687:1696	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	108	theme	PCWP-related	1577:1588	arg1	metabolites					1590:1600	Thirty-eight PCWP-related metabolites	1564:1600	Thirty-eight PCWP-related metabolites	1564:1600	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	108	theme	PCWP-related	1577:1588	arg1	metabolism					1746:1755	glycerophospholipid metabolism	1726:1755	glycerophospholipid metabolism	1726:1755	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	7	108	theme	PCWP-related	1577:1588	arg1	metabolism					1710:1719	vitamin B6 metabolism	1699:1719	vitamin B6 metabolism	1699:1719	Thirty-eight PCWP-related metabolites and four metabolic pathways such as sphingolipid metabolism, taurine and hypotaurine metabolism, vitamin B6 metabolism, and glycerophospholipid metabolism were explored.					
35642970	3	109	from	cocos	462:466	arg1	effects					395:401	effects	395:401	effects	395:401	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	109	from	cocos	462:466	arg1	polysaccharide					439:452	the water-soluble polysaccharide	421:452	the water-soluble polysaccharide from P. cocos (PCWP)	421:473	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	109	from	cocos	462:466	arg1	mechanisms					407:416	mechanisms	407:416	mechanisms	407:416	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	5	110	theme	species	1150:1156	arg1	richness					1158:1165	species richness	1150:1165	species richness	1150:1165	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	6	111	used	used	1460:1463	arg2	Metabolomics					1443:1454	Metabolomics	1443:1454	Metabolomics	1443:1454	Metabolomics was used to analyze fecal samples to identify significantly altered metabolites in the PCWP-treated groups.					
35642970	9	112	theme	pathway	1950:1956	arg1	enrichment					1958:1967	metabolic pathway enrichment	1940:1967	metabolic pathway enrichment	1940:1967	The regulatory effects of metabolic pathway enrichment on sphingolipid, phenylalanine, and taurine and hypotaurine metabolism, and validation results showed that PCWP intervention regulated the activity of enzymes involved in the above metabolic pathways.					
35642970	6	113	theme	altered	1516:1522	arg1	metabolites					1524:1534	significantly altered metabolites	1502:1534	significantly altered metabolites	1502:1534	Metabolomics was used to analyze fecal samples to identify significantly altered metabolites in the PCWP-treated groups.					
35642970	3	114	theme	polysaccharide	439:452	arg1	effects					395:401	effects	395:401	effects	395:401	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	3	114	theme	polysaccharide	439:452	arg1	mechanisms					407:416	mechanisms	407:416	mechanisms	407:416	The effects and mechanisms of the water-soluble polysaccharide from P. cocos (PCWP) were investigated in chronic sleep deprivation (CSD)-induced anxiety in rats.					
35642970	4	115	theme	γ-aminobutyric	791:804	arg1	acid					806:809	γ-aminobutyric acid	791:809	γ-aminobutyric acid	791:809	CSD induced anxiety, gut dysbiosis, and inflammatory responses, and reduced neurotransmitter levels, whereas PCWP intervention ameliorated anxiety-like behaviors, increased the levels of 5-hydroxytryptamine, dopamine, norepinephrine, and γ-aminobutyric acid in the hypothalamus, regulated gastrointestinal peptide levels, reduced inflammatory factors, and inhibited the tumor necrosis factor (TNF)-α/nuclear factor (NF)-κB signaling pathway in rats with CSD.					
35642970	5	116	with	rats	1208:1211	arg1	anxiety					1218:1224	anxiety	1218:1224	anxiety	1218:1224	The changes in the intestinal flora composition were determined using 16S rDNA sequencing, and indicated that PCWP significantly improved species richness and diversity in the intestinal flora of rats with anxiety, and adjusted the abundance of the following dysregulated bacteria closer to that of the normal group: Rikenellaceae_RC9_gut_group, Ruminococcus, Prevotellaceae_UCG-001, Prevotellaceae_NK3B31_group, Fusicatenibacter.					
35642970	1	117	theme	folk	244:247	arg1	cocos					196:200	Poria cocos	190:200	Poria cocos (P. cocos)	190:211	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
35642970	1	117	theme	folk	244:247	arg1	medicine					249:256	folk medicine	244:256	folk medicine	244:256	Poria cocos (P. cocos) has been traditionally used as folk medicine and functional food in China for more than 2000 years.					
37003376	6	0	theme	different	1096:1104	arg1	formulations					1116:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	0	theme	different	1096:1104	arg1	ratio					1136:1140	LG/SA ratio 1:3	1130:1144	LG/SA ratio 1:3	1130:1144	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	0	theme	different	1096:1104	arg1	1:2					1147:1149	1:2	1147:1149	1:2	1147:1149	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	0	theme	different	1096:1104	arg1	1:1					1155:1157	1:1	1155:1157	1:1	1155:1157	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	5	1	theme	mixture	1051:1057	arg1	deposition					969:978	the layer-by-layer deposition	950:978	the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter	950:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	1	2	theme	mineralized	155:165	arg1	bone					115:118	The bone	111:118	The bone	111:118	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	1	2	theme	mineralized	155:165	arg1	tissue					167:172	a connective, vascularized, and mineralized tissue	123:172	a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis	123:329	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	9	3	from	application	1728:1738	arg1	development					1747:1757	the development	1743:1757	the development of 3D scaffolds aimed for bone regeneration	1743:1801	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	0	4	theme	tissue	90:95	arg1	regeneration					97:108	bone tissue regeneration	85:108	bone tissue regeneration	85:108	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	7	5	theme	15 	1409:1411	arg1	%					1412:1412	%	1412:1412	%	1412:1412	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	5	6	theme	3D	888:889	arg1	structures					891:900	these 3D structures	882:900	these 3D structures	882:900	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	5	7	dep	reinforce	828:836	arg1	to					825:826	to	825:826	to	825:826	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	4	8	theme	3D	750:751	arg1	structures					753:762	customized 3D structures	739:762	customized 3D structures with osteoinductive and osteoconductive properties	739:813	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	5	9	theme	tricalcium	985:994	arg1	phosphate					996:1004	a tricalcium phosphate	983:1004	a tricalcium phosphate (TCP)	983:1010	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	5	9	theme	tricalcium	985:994	arg1	TCP					1007:1009	TCP	1007:1009	TCP	1007:1009	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	6	10	theme	TCP/LG/SA	1106:1114	arg1	formulations					1116:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	10	theme	TCP/LG/SA	1106:1114	arg1	ratio					1136:1140	LG/SA ratio 1:3	1130:1144	LG/SA ratio 1:3	1130:1144	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	10	theme	TCP/LG/SA	1106:1114	arg1	1:2					1147:1149	1:2	1147:1149	1:2	1147:1149	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	10	theme	TCP/LG/SA	1106:1114	arg1	1:1					1155:1157	1:1	1155:1157	1:1	1155:1157	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	4	11	with	structures	753:762	arg1	properties					804:813	osteoinductive and osteoconductive properties	769:813	osteoinductive and osteoconductive properties	769:813	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	0	12	from	application	70:80	arg1	regeneration					97:108	bone tissue regeneration	85:108	bone tissue regeneration	85:108	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	6	13	theme	LG/SA	1130:1134	arg1	formulations					1116:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations	1090:1127	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	6	13	theme	LG/SA	1130:1134	arg1	ratio					1136:1140	LG/SA ratio 1:3	1130:1144	LG/SA ratio 1:3	1130:1144	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	4	14	dep	materials	665:673	arg1	consisting					676:685	consisting	676:685	consisting of ceramics and polymers	676:710	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	9	15	theme	Such	1686:1689	arg1	results					1691:1697	Such results	1686:1697	Such results	1686:1697	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	1	16	theme	human	263:267	arg1	body					269:272	the human body	259:272	the human body	259:272	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	5	17	theme	lignin	1039:1044	arg1	mixture					1051:1057	lignin (LG) mixture	1039:1057	lignin (LG) mixture	1039:1057	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	4	18	theme	customized	739:748	arg1	structures					753:762	customized 3D structures	739:762	customized 3D structures with osteoinductive and osteoconductive properties	739:813	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	4	19	theme	Rapid	620:624	arg1	techniques					638:647	Rapid prototyping techniques	620:647	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers)	620:711	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	9	20	theme	LG	1711:1712	arg1	inclusion					1714:1722	LG inclusion	1711:1722	LG inclusion	1711:1722	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	9	21	from	inclusion	1714:1722	arg1	development					1747:1757	the development	1743:1757	the development of 3D scaffolds aimed for bone regeneration	1743:1801	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	8	22	dep	bioactivity	1634:1644	arg1	formation					1647:1655	formation	1647:1655	formation of hydroxyapatite crystals	1647:1682	Moreover, all TCP/LG/SA formulations showed an enhanced wettability and maintained their capacity to promote the osteoblasts' adhesion and proliferation as well as their bioactivity (formation of hydroxyapatite crystals).					
37003376	2	23	theme	mechanical	405:414	arg1	traumas					396:402	traumas	396:402	traumas (mechanical fractures)	396:425	However, throughout the lifetime, bone defects may arise due to traumas (mechanical fractures), diseases, and/or aging, which when too extensive compromise the ability of the bone to self-regenerate.					
37003376	2	23	theme	mechanical	405:414	arg1	fractures					416:424	mechanical fractures	405:424	mechanical fractures	405:424	However, throughout the lifetime, bone defects may arise due to traumas (mechanical fractures), diseases, and/or aging, which when too extensive compromise the ability of the bone to self-regenerate.					
37003376	2	24	theme	bone	366:369	arg1	defects					371:377	bone defects	366:377	bone defects	366:377	However, throughout the lifetime, bone defects may arise due to traumas (mechanical fractures), diseases, and/or aging, which when too extensive compromise the ability of the bone to self-regenerate.					
37003376	0	25	theme	tricalcium	16:25	arg1	3D					53:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	5	26	theme	LG	1047:1048	arg1	mixture					1051:1057	lignin (LG) mixture	1039:1057	lignin (LG) mixture	1039:1057	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	9	27	theme	bone	1785:1788	arg1	regeneration					1790:1801	bone regeneration	1785:1801	bone regeneration	1785:1801	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	7	28	theme	mechanical	1330:1339	arg1	resistance					1341:1350	the mechanical resistance	1326:1350	the mechanical resistance of the scaffolds	1326:1367	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	7	29	theme	1:2	1390:1392	arg1	ratio					1394:1398	the 1:2 ratio	1386:1398	the 1:2 ratio	1386:1398	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	0	30	theme	Lignin-enriched	0:14	arg1	3D					53:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	1	31	theme	body	269:272	arg1	support					233:239	support	233:239	support	233:239	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	1	31	theme	body	269:272	arg1	maintenance					275:285	maintenance	275:285	maintenance of homeostasis	275:300	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	7	32	theme	%	1412:1412	arg1	increase					1414:1421	a 15 % increase	1407:1421	a 15 % increase in the mechanical strength	1407:1448	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	5	33	theme	new	913:915	arg1	scaffold					920:927	a new 3D scaffold	911:927	a new 3D scaffold	911:927	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	4	34	theme	prototyping	626:636	arg1	techniques					638:647	Rapid prototyping techniques	620:647	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers)	620:711	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	0	35	theme	alginate	44:51	arg1	3D					53:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	5	36	theme	3D	917:918	arg1	scaffold					920:927	a new 3D scaffold	911:927	a new 3D scaffold	911:927	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	4	37	theme	osteoconductive	788:802	arg1	properties					804:813	osteoinductive and osteoconductive properties	769:813	osteoinductive and osteoconductive properties	769:813	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	0	38	theme	phosphate/sodium	27:42	arg1	3D					53:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D	0:54	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	1	39	dep	support	233:239	arg1	the					229:231	the	229:231	the	229:231	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	8	40	theme	hydroxyapatite	1660:1673	arg1	crystals					1675:1682	hydroxyapatite crystals	1660:1682	hydroxyapatite crystals	1660:1682	Moreover, all TCP/LG/SA formulations showed an enhanced wettability and maintained their capacity to promote the osteoblasts' adhesion and proliferation as well as their bioactivity (formation of hydroxyapatite crystals).					
37003376	7	41	from	increase	1414:1421	arg1	strength					1441:1448	the mechanical strength	1426:1448	the mechanical strength	1426:1448	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	2	42	dep	compromise	477:486	arg1	aging					445:449	aging	445:449	aging	445:449	However, throughout the lifetime, bone defects may arise due to traumas (mechanical fractures), diseases, and/or aging, which when too extensive compromise the ability of the bone to self-regenerate.					
37003376	3	43	theme	such	543:546	arg1	situation					557:565	such clinical situation	543:565	such clinical situation	543:565	To surpass such clinical situation, different therapeutic approaches have been pursued.					
37003376	5	44	theme	osteogenic	857:866	arg1	properties					868:877	the mechanical and osteogenic properties	838:877	the mechanical and osteogenic properties of these 3D structures	838:900	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	1	45	theme	homeostasis	290:300	arg1	maintenance					275:285	maintenance	275:285	maintenance of homeostasis	275:300	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	1	45	theme	homeostasis	290:300	arg1	support					233:239	support	233:239	support	233:239	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	6	46	theme	bone	1236:1239	arg1	regeneration					1241:1252	bone regeneration	1236:1252	bone regeneration	1236:1252	Three different TCP/LG/SA formulations, LG/SA ratio 1:3, 1:2, or 1:1, were produced and subsequently evaluated to determine their suitability for bone regeneration.					
37003376	3	47	theme	clinical	548:555	arg1	situation					557:565	such clinical situation	543:565	such clinical situation	543:565	To surpass such clinical situation, different therapeutic approaches have been pursued.					
37003376	5	48	theme	Fab	1069:1071	arg1	3D-Plotter					1078:1087	the Fab@Home 3D-Plotter	1065:1087	the Fab@Home 3D-Plotter	1065:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	7	49	theme	mechanical	1430:1439	arg1	strength					1441:1448	the mechanical strength	1426:1448	the mechanical strength	1426:1448	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	8	50	theme	crystals	1675:1682	arg1	formation					1647:1655	formation	1647:1655	formation of hydroxyapatite crystals	1647:1682	Moreover, all TCP/LG/SA formulations showed an enhanced wettability and maintained their capacity to promote the osteoblasts' adhesion and proliferation as well as their bioactivity (formation of hydroxyapatite crystals).					
37003376	5	51	theme	structures	891:900	arg1	properties					868:877	the mechanical and osteogenic properties	838:877	the mechanical and osteogenic properties of these 3D structures	838:900	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	9	52	theme	3D	1762:1763	arg1	scaffolds					1765:1773	3D scaffolds	1762:1773	3D scaffolds aimed for bone regeneration	1762:1801	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	5	53	theme	Home	1073:1076	arg1	3D-Plotter					1078:1087	the Fab@Home 3D-Plotter	1065:1087	the Fab@Home 3D-Plotter	1065:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	7	54	theme	LG	1304:1305	arg1	inclusion					1307:1315	the LG inclusion	1300:1315	the LG inclusion	1300:1315	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	1	55	theme	connective	125:134	arg1	bone					115:118	The bone	111:118	The bone	111:118	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	1	55	theme	connective	125:134	arg1	tissue					167:172	a connective, vascularized, and mineralized tissue	123:172	a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis	123:329	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	9	56	theme	scaffolds	1765:1773	arg1	development					1747:1757	the development	1743:1757	the development of 3D scaffolds aimed for bone regeneration	1743:1801	Such results support the LG inclusion and application in the development of 3D scaffolds aimed for bone regeneration.					
37003376	7	57	theme	scaffolds	1359:1367	arg1	resistance					1341:1350	the mechanical resistance	1326:1350	the mechanical resistance of the scaffolds	1326:1367	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	5	58	theme	layer-by-layer	954:967	arg1	deposition					969:978	the layer-by-layer deposition	950:978	the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter	950:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	3	59	theme	different	568:576	arg1	approaches					590:599	different therapeutic approaches	568:599	different therapeutic approaches	568:599	To surpass such clinical situation, different therapeutic approaches have been pursued.					
37003376	5	60	theme	phosphate	996:1004	arg1	deposition					969:978	the layer-by-layer deposition	950:978	the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter	950:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	8	61	theme	enhanced	1511:1518	arg1	wettability					1520:1530	an enhanced wettability	1508:1530	an enhanced wettability	1508:1530	Moreover, all TCP/LG/SA formulations showed an enhanced wettability and maintained their capacity to promote the osteoblasts' adhesion and proliferation as well as their bioactivity (formation of hydroxyapatite crystals).					
37003376	2	62	theme	bone	507:510	arg1	ability					492:498	the ability	488:498	the ability of the bone to self-regenerate	488:529	However, throughout the lifetime, bone defects may arise due to traumas (mechanical fractures), diseases, and/or aging, which when too extensive compromise the ability of the bone to self-regenerate.					
37003376	5	63	theme	sodium	1013:1018	arg1	SA					1030:1031	SA	1030:1031	SA	1030:1031	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	5	63	theme	sodium	1013:1018	arg1	alginate					1020:1027	sodium alginate	1013:1027	sodium alginate (SA)	1013:1032	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	3	64	theme	therapeutic	578:588	arg1	approaches					590:599	different therapeutic approaches	568:599	different therapeutic approaches	568:599	To surpass such clinical situation, different therapeutic approaches have been pursued.					
37003376	1	65	theme	vascularized	137:148	arg1	bone					115:118	The bone	111:118	The bone	111:118	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	1	65	theme	vascularized	137:148	arg1	tissue					167:172	a connective, vascularized, and mineralized tissue	123:172	a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis	123:329	The bone is a connective, vascularized, and mineralized tissue that confers protection to organs, and participates in the support and locomotion of the human body, maintenance of homeostasis, as well as in hematopoiesis.					
37003376	4	66	used	used	723:726	arg2	techniques					638:647	Rapid prototyping techniques	620:647	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers)	620:711	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	0	67	theme	bone	85:88	arg1	regeneration					97:108	bone tissue regeneration	85:108	bone tissue regeneration	85:108	Lignin-enriched tricalcium phosphate/sodium alginate 3D scaffolds for application in bone tissue regeneration.					
37003376	5	68	theme	alginate	1020:1027	arg1	deposition					969:978	the layer-by-layer deposition	950:978	the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter	950:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	4	69	theme	osteoinductive	769:782	arg1	properties					804:813	osteoinductive and osteoconductive properties	769:813	osteoinductive and osteoconductive properties	769:813	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	4	70	theme	composite	655:663	arg1	materials					665:673	composite materials (consisting of ceramics and polymers)	655:711	composite materials (consisting of ceramics and polymers)	655:711	Rapid prototyping techniques using composite materials (consisting of ceramics and polymers) have been used to produce customized 3D structures with osteoinductive and osteoconductive properties.					
37003376	5	71	theme	mechanical	842:851	arg1	properties					868:877	the mechanical and osteogenic properties	838:877	the mechanical and osteogenic properties of these 3D structures	838:900	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
37003376	8	72	theme	TCP/LG/SA	1478:1486	arg1	formulations					1488:1499	all TCP/LG/SA formulations	1474:1499	all TCP/LG/SA formulations	1474:1499	Moreover, all TCP/LG/SA formulations showed an enhanced wettability and maintained their capacity to promote the osteoblasts' adhesion and proliferation as well as their bioactivity (formation of hydroxyapatite crystals).					
37003376	7	73	theme	physicochemical	1259:1273	arg1	assays					1275:1280	The physicochemical assays	1255:1280	The physicochemical assays	1255:1280	The physicochemical assays demonstrated that the LG inclusion improved the mechanical resistance of the scaffolds, particularly in the 1:2 ratio, since a 15 % increase in the mechanical strength was observed.					
37003376	5	74	theme	@	1072:1072	arg1	3D-Plotter					1078:1087	the Fab@Home 3D-Plotter	1065:1087	the Fab@Home 3D-Plotter	1065:1087	In order to reinforce the mechanical and osteogenic properties of these 3D structures, herein, a new 3D scaffold was produced through the layer-by-layer deposition of a tricalcium phosphate (TCP), sodium alginate (SA), and lignin (LG) mixture using the Fab@Home 3D-Plotter.					
36169339	12	0	theme	volatile	1929:1936	arg1	compounds					1945:1953	the volatile flavor compounds	1925:1953	the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1925:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	11	1	theme	flavor	1756:1761	arg1	information					1763:1773	the characteristic flavor information	1737:1773	the characteristic flavor information of cattle by-products	1737:1795	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	15	2	theme	characteristic	2467:2480	arg1	compounds					2493:2501	the characteristic off-flavor compounds	2463:2501	the characteristic off-flavor compounds	2463:2501	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	6	3	from	compound	1128:1135	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	3	from	compound	1128:1135	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	9	4	theme	characteristic	1531:1544	arg1	compounds					1546:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds decreased in concentration.					
36169339	14	5	theme	different	2292:2300	arg1	methods					2316:2322	Four different deodorization methods	2287:2322	Four different deodorization methods	2287:2322	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	2	6	theme	by-products	285:295	arg1	off-flavor					297:306	cattle by-products off-flavor	278:306	cattle by-products off-flavor (heart, liver, lung, rumen, and intestine)	278:349	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	15	7	theme	various	2572:2578	arg1	methods					2594:2600	various deodorization methods	2572:2600	various deodorization methods	2572:2600	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	14	8	theme	composite	2376:2384	arg1	method					2386:2391	ultrasound + chitosan composite method	2354:2391	ultrasound + chitosan composite method	2354:2391	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	4	9	theme	squares-discriminant	757:776	arg1	analysis					778:785	partial least squares-discriminant analysis	743:785	partial least squares-discriminant analysis (PLS-DA)	743:794	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	9	theme	squares-discriminant	757:776	arg1	PLS-DA					788:793	PLS-DA	788:793	PLS-DA	788:793	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	7	10	theme	bovine	1301:1306	arg1	intestine					1308:1316	bovine intestine	1301:1316	bovine intestine	1301:1316	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	15	11	theme	by-products	2552:2562	arg1	flavor					2535:2540	the flavor	2531:2540	the flavor of cattle by-products	2531:2562	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	1	12	theme	compounds	163:171	arg1	presence					139:146	the presence	135:146	the presence of undesirable compounds	135:171	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	4	13	theme	odor	605:608	arg1	value					619:623	the relative odor activity value	592:623	the relative odor activity value (ROAV ≥ 1)	592:634	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	13	theme	odor	605:608	arg1	≥ 1					631:633	ROAV ≥ 1	626:633	ROAV ≥ 1	626:633	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	14	theme	partial	743:749	arg1	analysis					778:785	partial least squares-discriminant analysis	743:785	partial least squares-discriminant analysis (PLS-DA)	743:794	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	14	theme	partial	743:749	arg1	PLS-DA					788:793	PLS-DA	788:793	PLS-DA	788:793	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	5	15	dep	hexanal	917:923	arg1	-2-octenal					929:938	-2-octenal	929:938	-2-octenal	929:938	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	12	16	theme	chromatography-mass	2082:2100	arg1	HS-SPME/GC-MS					2116:2128	HS-SPME/GC-MS	2116:2128	HS-SPME/GC-MS	2116:2128	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	16	theme	chromatography-mass	2082:2100	arg1	spectrometry					2102:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry	2040:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	2040:2129	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	10	17	theme	composite	1610:1618	arg1	method					1620:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	8	18	theme	cattle	1323:1328	arg1	by-products					1330:1340	The cattle by-products	1319:1340	The cattle by-products	1319:1340	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	6	19	theme	off-flavor	1117:1126	arg1	compound					1128:1135	the off-flavor compound	1113:1135	the off-flavor compound	1113:1135	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	3	20	theme	solid-phase	501:511	arg1	HS-SPME/GC-MS					567:579	HS-SPME/GC-MS	567:579	HS-SPME/GC-MS	567:579	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	3	20	theme	solid-phase	501:511	arg1	spectrometry					553:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry	491:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	491:580	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	21	from	organs	1987:1992	arg1	compounds					1945:1953	the volatile flavor compounds	1925:1953	the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1925:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	21	from	organs	1987:1992	arg1	by-products					1965:1975	cattle by-products	1958:1975	cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1958:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	13	22	theme	relative	2223:2230	arg1	values					2246:2251	relative odor activity values	2223:2251	relative odor activity values	2223:2251	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	1	23	theme	drink	111:115	arg1	product					117:123	a food or drink product	101:123	product	117:123	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	12	24	theme	cattle	1958:1963	arg1	by-products					1965:1975	cattle by-products	1958:1975	cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1958:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	6	25	theme	lung	1087:1090	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	14	26	theme	deodorization	2302:2314	arg1	methods					2316:2322	Four different deodorization methods	2287:2322	Four different deodorization methods	2287:2322	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	5	27	theme	decyl	945:949	arg1	aldehyde					951:958	decyl aldehyde	945:958	decyl aldehyde	945:958	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	5	28	theme	bovine	856:861	arg1	heart					863:867	bovine heart	856:867	bovine heart	856:867	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	7	29	from	compounds	1286:1294	arg1	rumen					1148:1152	bovine rumen	1141:1152	bovine rumen	1141:1152	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	0	30	theme	by-products	65:75	arg1	deodorizing					43:53	deodorizing	43:53	deodorizing of cattle by-products	43:75	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	0	30	theme	by-products	65:75	arg1	Identification					0:13	Identification	0:13	Identification of off-flavor compounds	0:37	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	11	31	theme	deodorization	1854:1866	arg1	methods					1868:1874	various deodorization methods	1846:1874	various deodorization methods	1846:1874	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	12	32	from	compounds	1945:1953	arg1	lung					2009:2012	lung	2009:2012	lung	2009:2012	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	32	from	compounds	1945:1953	arg1	rumen					2015:2019	rumen	2015:2019	rumen	2015:2019	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	32	from	compounds	1945:1953	arg1	heart					1995:1999	heart	1995:1999	heart	1995:1999	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	32	from	compounds	1945:1953	arg1	liver					2002:2006	liver	2002:2006	liver	2002:2006	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	32	from	compounds	1945:1953	arg1	intestine					2026:2034	intestine	2026:2034	intestine	2026:2034	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	32	from	compounds	1945:1953	arg1	organs					1987:1992	five organs	1982:1992	five organs (heart, liver, lung, rumen, and intestine)	1982:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	4	33	theme	ROAV	626:629	arg1	value					619:623	the relative odor activity value	592:623	the relative odor activity value (ROAV ≥ 1)	592:634	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	33	theme	ROAV	626:629	arg1	≥ 1					631:633	ROAV ≥ 1	626:633	ROAV ≥ 1	626:633	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	34	theme	characteristic	675:688	arg1	off-flavor					690:699	characteristic off-flavor	675:699	characteristic off-flavor	675:699	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	34	theme	characteristic	675:688	arg1	compounds					649:657	16 volatile compounds	637:657	16 volatile compounds	637:657	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	6	35	theme	dodecyl	1056:1062	arg1	aldehyde					1064:1071	dodecyl aldehyde	1056:1071	dodecyl aldehyde	1056:1071	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	15	36	theme	useful	2438:2443	arg1	information					2445:2455	useful information	2438:2455	useful information about the characteristic off-flavor compounds	2438:2501	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	7	37	from	compounds	1218:1226	arg1	rumen					1148:1152	bovine rumen	1141:1152	bovine rumen	1141:1152	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	13	38	theme	characteristic	2184:2197	arg1	compounds					2210:2218	the major characteristic off-flavor compounds	2174:2218	the major characteristic off-flavor compounds	2174:2218	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	13	38	theme	characteristic	2184:2197	arg1	compounds					2148:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	8	39	dep	ultrasound	1477:1486	arg1	composite					1499:1507	composite	1499:1507	composite	1499:1507	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	1	40	theme	unnatural	81:89	arg1	flavor					91:96	An unnatural flavor	78:96	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration	78:209	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	7	41	theme	off-flavor	1207:1216	arg1	compounds					1218:1226	off-flavor compounds	1207:1226	off-flavor compounds	1207:1226	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	8	42	theme	active	1421:1426	arg1	yeast					1432:1436	active dry yeast + β-cyclodextrin (β-CD) composite	1421:1470	yeast	1432:1436	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	11	43	theme	cattle	1778:1783	arg1	by-products					1785:1795	cattle by-products	1778:1795	cattle by-products	1778:1795	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	3	44	theme	microextraction/gas	513:531	arg1	HS-SPME/GC-MS					567:579	HS-SPME/GC-MS	567:579	HS-SPME/GC-MS	567:579	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	3	44	theme	microextraction/gas	513:531	arg1	spectrometry					553:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry	491:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	491:580	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	0	45	theme	off-flavor	18:27	arg1	compounds					29:37	off-flavor compounds	18:37	off-flavor compounds	18:37	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	10	46	theme	better	1650:1655	arg1	effect					1657:1662	a significantly better effect	1634:1662	a significantly better effect	1634:1662	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	1	47	theme	food	103:106	arg1	product					117:123	a food or drink product	101:123	product	117:123	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	8	48	theme	β-cyclodextrin	1440:1453	arg1	composite					1462:1470	active dry yeast + β-cyclodextrin (β-CD) composite	1421:1470	composite	1462:1470	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	12	49	dep	APPLICATIONS	1887:1898	arg1	investigated					1912:1923	investigated	1912:1923	investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	1912:2129	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	50	theme	headspace	2040:2048	arg1	HS-SPME/GC-MS					2116:2128	HS-SPME/GC-MS	2116:2128	HS-SPME/GC-MS	2116:2128	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	50	theme	headspace	2040:2048	arg1	spectrometry					2102:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry	2040:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	2040:2129	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	13	51	theme	odor	2232:2235	arg1	values					2246:2251	relative odor activity values	2223:2251	relative odor activity values	2223:2251	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	8	52	theme	β-CD	1456:1459	arg1	composite					1462:1470	active dry yeast + β-cyclodextrin (β-CD) composite	1421:1470	composite	1462:1470	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	12	53	theme	microextraction/gas	2062:2080	arg1	HS-SPME/GC-MS					2116:2128	HS-SPME/GC-MS	2116:2128	HS-SPME/GC-MS	2116:2128	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	53	theme	microextraction/gas	2062:2080	arg1	spectrometry					2102:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry	2040:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	2040:2129	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	10	54	theme	chitosan	1601:1608	arg1	method					1620:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	3	55	theme	chromatography-mass	533:551	arg1	HS-SPME/GC-MS					567:579	HS-SPME/GC-MS	567:579	HS-SPME/GC-MS	567:579	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	3	55	theme	chromatography-mass	533:551	arg1	spectrometry					553:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry	491:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	491:580	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	4	56	theme	component	714:722	arg1	analysis					724:731	principal component analysis	704:731	principal component analysis (PCA)	704:737	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	56	theme	component	714:722	arg1	PCA					734:736	PCA	734:736	PCA	734:736	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	6	57	from	1-nonanol	1012:1020	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	57	from	1-nonanol	1012:1020	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	10	58	theme	ultrasound	1588:1597	arg1	method					1620:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method	1584:1625	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	13	59	theme	component	2267:2275	arg1	analysis					2277:2284	principal component analysis	2257:2284	principal component analysis	2257:2284	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	4	60	theme	activity	610:617	arg1	value					619:623	the relative odor activity value	592:623	the relative odor activity value (ROAV ≥ 1)	592:634	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	60	theme	activity	610:617	arg1	≥ 1					631:633	ROAV ≥ 1	626:633	ROAV ≥ 1	626:633	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	13	61	theme	activity	2237:2244	arg1	values					2246:2251	relative odor activity values	2223:2251	relative odor activity values	2223:2251	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	9	62	theme	above	1514:1518	arg1	compounds					1546:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds decreased in concentration.					
36169339	7	63	theme	bovine	1141:1146	arg1	rumen					1148:1152	bovine rumen	1141:1152	bovine rumen	1141:1152	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	11	64	theme	characteristic	1741:1754	arg1	information					1763:1773	the characteristic flavor information	1737:1773	the characteristic flavor information of cattle by-products	1737:1795	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	14	65	theme	best	2400:2403	arg1	results					2405:2411	best results	2400:2411	best results	2400:2411	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	9	66	theme	labeled	1523:1529	arg1	compounds					1546:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds	1510:1554	The above 16 labeled characteristic compounds decreased in concentration.					
36169339	3	67	from	lung	431:434	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	2	68	theme	off-flavor	297:306	arg1	characteristics					259:273	the characteristics	255:273	the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine)	255:349	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	15	69	theme	off-flavor	2482:2491	arg1	compounds					2493:2501	the characteristic off-flavor compounds	2463:2501	the characteristic off-flavor compounds	2463:2501	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	12	70	theme	PRACTICAL	1877:1885	arg1	APPLICATIONS					1887:1898	PRACTICAL APPLICATIONS	1877:1898	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).	1877:2130	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	2	71	dep	off-flavor	297:306	arg1	heart					309:313	heart	309:313	heart	309:313	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	2	71	dep	off-flavor	297:306	arg1	rumen					329:333	rumen	329:333	rumen	329:333	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	2	71	dep	off-flavor	297:306	arg1	intestine					340:348	intestine	340:348	intestine	340:348	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	2	71	dep	off-flavor	297:306	arg1	lung					323:326	lung	323:326	lung	323:326	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	2	71	dep	off-flavor	297:306	arg1	liver					316:320	liver	316:320	liver	316:320	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	3	72	from	rumen	437:441	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	2	73	theme	cattle	278:283	arg1	off-flavor					297:306	cattle by-products off-flavor	278:306	cattle by-products off-flavor (heart, liver, lung, rumen, and intestine)	278:349	This study determined the characteristics of cattle by-products off-flavor (heart, liver, lung, rumen, and intestine).					
36169339	15	74	theme	deodorization	2580:2592	arg1	methods					2594:2600	various deodorization methods	2572:2600	various deodorization methods	2572:2600	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	1	75	theme	undesirable	151:161	arg1	compounds					163:171	undesirable compounds	151:171	undesirable compounds	151:171	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	14	76	theme	chitosan	2367:2374	arg1	method					2386:2391	ultrasound + chitosan composite method	2354:2391	ultrasound + chitosan composite method	2354:2391	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	3	77	from	heart	417:421	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	4	78	theme	relative	596:603	arg1	value					619:623	the relative odor activity value	592:623	the relative odor activity value (ROAV ≥ 1)	592:634	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	78	theme	relative	596:603	arg1	≥ 1					631:633	ROAV ≥ 1	626:633	ROAV ≥ 1	626:633	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	3	79	from	liver	424:428	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	10	80	theme	other	1673:1677	arg1	p < .05					1688:1694	p < .05	1688:1694	p < .05	1688:1694	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	10	80	theme	other	1673:1677	arg1	methods					1679:1685	the other methods	1669:1685	the other methods (p < .05)	1669:1695	The ultrasound + chitosan composite method showed a significantly better effect than the other methods (p < .05).					
36169339	15	81	theme	cattle	2545:2550	arg1	by-products					2552:2562	cattle by-products	2545:2562	cattle by-products	2545:2562	This study has provided useful information about the characteristic off-flavor compounds and suggests how to improve the flavor of cattle by-products through various deodorization methods.					
36169339	13	82	theme	off-flavor	2199:2208	arg1	compounds					2210:2218	the major characteristic off-flavor compounds	2174:2218	the major characteristic off-flavor compounds	2174:2218	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	13	82	theme	off-flavor	2199:2208	arg1	compounds					2148:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	6	83	theme	ethyl	1023:1027	arg1	hexanoate					1029:1037	ethyl hexanoate	1023:1037	ethyl hexanoate	1023:1037	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	3	84	theme	headspace	491:499	arg1	HS-SPME/GC-MS					567:579	HS-SPME/GC-MS	567:579	HS-SPME/GC-MS	567:579	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	3	84	theme	headspace	491:499	arg1	spectrometry					553:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry	491:564	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	491:580	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	11	85	theme	study	1714:1718	arg1	aim					1702:1704	The aim	1698:1704	The aim of this study	1698:1718	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	5	86	theme	characteristic	827:840	arg1	off-flavor					842:851	the characteristic off-flavor	823:851	the characteristic off-flavor in bovine heart	823:867	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	8	87	theme	shallot-ginger	1361:1374	arg1	extract					1376:1382	shallot-ginger extract masking	1361:1390	shallot-ginger extract masking	1361:1390	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	12	88	theme	by-products	1965:1975	arg1	compounds					1945:1953	the volatile flavor compounds	1925:1953	the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1925:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	13	89	theme	major	2178:2182	arg1	compounds					2210:2218	the major characteristic off-flavor compounds	2174:2218	the major characteristic off-flavor compounds	2174:2218	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	13	89	theme	major	2178:2182	arg1	compounds					2148:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	8	90	theme	masking	1384:1390	arg1	extract					1376:1382	shallot-ginger extract masking	1361:1390	shallot-ginger extract masking	1361:1390	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	6	91	theme	bovine	1080:1085	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	7	92	with	compounds	1218:1226	arg1	intestine					1308:1316	bovine intestine	1301:1316	bovine intestine	1301:1316	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	7	93	with	compounds	1286:1294	arg1	intestine					1308:1316	bovine intestine	1301:1316	bovine intestine	1301:1316	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	11	94	theme	various	1846:1852	arg1	methods					1868:1874	various deodorization methods	1846:1874	various deodorization methods	1846:1874	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	13	95	theme	volatile	2139:2146	arg1	compounds					2148:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds	2132:2156	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	13	95	theme	volatile	2139:2146	arg1	compounds					2210:2218	the major characteristic off-flavor compounds	2174:2218	the major characteristic off-flavor compounds	2174:2218	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	12	96	theme	flavor	1938:1943	arg1	compounds					1945:1953	the volatile flavor compounds	1925:1953	the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine)	1925:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	8	97	theme	yeast	1401:1405	arg1	fermentation					1407:1418	baker's yeast fermentation	1393:1418	baker's yeast fermentation	1393:1418	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	3	98	from	intestine	448:456	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	7	99	theme	off-flavor	1275:1284	arg1	compounds					1286:1294	off-flavor compounds	1275:1294	off-flavor compounds with bovine intestine	1275:1316	In bovine rumen, heptaldehyde, octanal, p-cresol, and 1-nonanal were off-flavor compounds, and lastly, 1-octen-3-ol and E-2-nonenal were off-flavor compounds with bovine intestine.					
36169339	6	100	theme	bovine	968:973	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	8	101	theme	dry	1428:1430	arg1	yeast					1432:1436	active dry yeast + β-cyclodextrin (β-CD) composite	1421:1470	yeast	1432:1436	The cattle by-products were deodorized by shallot-ginger extract masking, baker's yeast fermentation, active dry yeast + β-cyclodextrin (β-CD) composite, and ultrasound + chitosan composite.					
36169339	6	102	from	aldehyde	1064:1071	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	102	from	aldehyde	1064:1071	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	12	103	dep	organs	1987:1992	arg1	lung					2009:2012	lung	2009:2012	lung	2009:2012	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	103	dep	organs	1987:1992	arg1	rumen					2015:2019	rumen	2015:2019	rumen	2015:2019	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	103	dep	organs	1987:1992	arg1	heart					1995:1999	heart	1995:1999	heart	1995:1999	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	103	dep	organs	1987:1992	arg1	liver					2002:2006	liver	2002:2006	liver	2002:2006	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	103	dep	organs	1987:1992	arg1	intestine					2026:2034	intestine	2026:2034	intestine	2026:2034	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	103	dep	organs	1987:1992	arg1	organs					1987:1992	five organs	1982:1992	five organs (heart, liver, lung, rumen, and intestine)	1982:2035	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	4	104	theme	volatile	640:647	arg1	off-flavor					690:699	characteristic off-flavor	675:699	characteristic off-flavor	675:699	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	104	theme	volatile	640:647	arg1	compounds					649:657	16 volatile compounds	637:657	16 volatile compounds	637:657	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	6	105	from	hexanoate	1029:1037	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	105	from	hexanoate	1029:1037	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	11	106	theme	by-products	1785:1795	arg1	information					1763:1773	the characteristic flavor information	1737:1773	the characteristic flavor information of cattle by-products	1737:1795	The aim of this study was to determine the characteristic flavor information of cattle by-products and provide idea on how to improve the flavor by various deodorization methods.					
36169339	0	107	theme	compounds	29:37	arg1	deodorizing					43:53	deodorizing	43:53	deodorizing of cattle by-products	43:75	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	0	107	theme	compounds	29:37	arg1	Identification					0:13	Identification	0:13	Identification of off-flavor compounds	0:37	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	5	108	from	off-flavor	842:851	arg1	heart					863:867	bovine heart	856:867	bovine heart	856:867	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	6	109	from	2-octanone	1040:1049	arg1	liver					975:979	the bovine liver	964:979	the bovine liver	964:979	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	109	from	2-octanone	1040:1049	arg1	3-heptylacrolein					1092:1107	bovine lung 3-heptylacrolein	1080:1107	bovine lung 3-heptylacrolein	1080:1107	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	14	110	theme	ultrasound	2354:2363	arg1	method					2386:2391	ultrasound + chitosan composite method	2354:2391	ultrasound + chitosan composite method	2354:2391	Four different deodorization methods were adopted, and among them, ultrasound + chitosan composite method showed best results.					
36169339	3	111	theme	volatile	389:396	arg1	compounds					398:406	25, 34, 26, 22, and 26 volatile compounds	366:406	25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine	366:456	We identified 25, 34, 26, 22, and 26 volatile compounds from the heart, liver, lung, rumen, and intestine, respectively, in the bovine via headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	0	112	theme	cattle	58:63	arg1	by-products					65:75	cattle by-products	58:75	cattle by-products	58:75	Identification of off-flavor compounds and deodorizing of cattle by-products.					
36169339	12	113	theme	solid-phase	2050:2060	arg1	HS-SPME/GC-MS					2116:2128	HS-SPME/GC-MS	2116:2128	HS-SPME/GC-MS	2116:2128	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	12	113	theme	solid-phase	2050:2060	arg1	spectrometry					2102:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry	2040:2113	headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS)	2040:2129	PRACTICAL APPLICATIONS: This study investigated the volatile flavor compounds of cattle by-products from five organs (heart, liver, lung, rumen, and intestine) by headspace solid-phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS).					
36169339	13	114	theme	principal	2257:2265	arg1	analysis					2277:2284	principal component analysis	2257:2284	principal component analysis	2257:2284	The 16 volatile compounds were labeled as the major characteristic off-flavor compounds by relative odor activity values and principal component analysis.					
36169339	4	115	theme	principal	704:712	arg1	analysis					724:731	principal component analysis	704:731	principal component analysis (PCA)	704:737	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	4	115	theme	principal	704:712	arg1	PCA					734:736	PCA	734:736	PCA	734:736	Based on the relative odor activity value (ROAV ≥ 1), 16 volatile compounds were labeled as characteristic off-flavor by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA).					
36169339	1	116	from	flavor	91:96	arg1	product					117:123	a food or drink product	101:123	product	117:123	An unnatural flavor in a food or drink product caused by the presence of undesirable compounds due to contamination or deterioration is called off-flavor.					
36169339	5	117	theme	hexanal	917:923	arg1	E					874:874	E	874:874	E	874:874	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	5	117	theme	hexanal	917:923	arg1	compounds					801:809	The compounds	797:809	The compounds involved in the characteristic off-flavor in bovine heart	797:867	The compounds involved in the characteristic off-flavor in bovine heart were E,E-2,4-nonadienal, E,E-2,4-decadien-1-al, hexanal, (E)-2-octenal, and decyl aldehyde.					
36169339	6	118	theme	off-flavor	986:995	arg1	1-nonanol					1012:1020	1-nonanol	1012:1020	1-nonanol	1012:1020	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
36169339	6	118	theme	off-flavor	986:995	arg1	compounds					997:1005	the off-flavor compounds	982:1005	the off-flavor compounds	982:1005	In the bovine liver, the off-flavor compounds were 1-nonanol, ethyl hexanoate, 2-octanone, and dodecyl aldehyde and in bovine lung 3-heptylacrolein was the off-flavor compound.					
35098649	0	0	theme	nasal	115:119	arg1	regeneration					131:142	nasal cartilage regeneration	115:142	nasal cartilage regeneration	115:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	5	1	theme	biochemical	1216:1226	arg1	features					1228:1235	appropriate biochemical features	1204:1235	appropriate biochemical features	1204:1235	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	4	2	dep	viscosity	896:904	arg1	had					885:887	had	885:887	had better viscosity, cell viability, and proliferation	885:939	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	3	theme	%	878:878	arg1	dECM					880:883	1% dECM	877:883	1% dECM	877:883	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	4	theme	stem	741:744	arg1	cells					746:750	the adipose-derived mesenchymal stem cells	709:750	the adipose-derived mesenchymal stem cells	709:750	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	5	with	scaffold	863:870	arg1	dECM					880:883	1% dECM	877:883	1% dECM	877:883	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	6	theme	live/dead	810:818	arg1	staining					820:827	live/dead staining	810:827	live/dead staining	810:827	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	7	theme	adipose-derived	713:727	arg1	cells					746:750	the adipose-derived mesenchymal stem cells	709:750	the adipose-derived mesenchymal stem cells	709:750	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	2	8	theme	deposition	324:333	arg1	method					344:349	fused deposition modeling method	318:349	fused deposition modeling method	318:349	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	2	9	theme	modeling	335:342	arg1	method					344:349	fused deposition modeling method	318:349	fused deposition modeling method	318:349	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	0	10	theme	cartilage	121:129	arg1	regeneration					131:142	nasal cartilage regeneration	115:142	nasal cartilage regeneration	115:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	2	11	theme	fused	318:322	arg1	method					344:349	fused deposition modeling method	318:349	fused deposition modeling method	318:349	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	4	12	link	adipose-derived	713:727	arg1	cells					746:750	the adipose-derived mesenchymal stem cells	709:750	the adipose-derived mesenchymal stem cells	709:750	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	5	13	theme	optimized	973:981	arg1	dECM					996:999	1% dECM	993:999	1% dECM	993:999	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	5	13	theme	optimized	973:981	arg1	scaffold					983:990	the optimized scaffold	969:990	the optimized scaffold (1% dECM)	969:1000	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	2	14	theme	Alginate-Sulfate	410:425	arg1	hydrogel					437:444	Alginate-Sulfate (Alg-Sul) hydrogel	410:444	Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly	410:544	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	2	15	theme	biomimetic	466:475	arg1	environment					477:487	a better biomimetic environment	457:487	a better biomimetic environment	457:487	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	4	16	theme	assay	803:807	arg1	images					838:843	MTT assay, live/dead staining, and SEM images	799:843	MTT assay, live/dead staining, and SEM images	799:843	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	17	theme	cellular	690:697	arg1	analyses					699:706	cellular analyses	690:706	cellular analyses	690:706	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	0	18	theme	additive	3:10	arg1	3D					32:33	An additive manufacturing-based 3D	0:33	An additive manufacturing-based 3D	0:33	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	4	19	theme	1	877:877	arg1	%					878:878	%	878:878	%	878:878	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	1	20	theme	cartilage	232:240	arg1	engineering					249:259	cartilage tissue engineering	232:259	cartilage tissue engineering	232:259	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	1	21	with	scaffolds	163:171	arg1	techniques					200:209	different fabrication techniques	178:209	different fabrication techniques	178:209	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	3	22	theme	decellularized	615:628	arg1	dECM					652:655	dECM	652:655	dECM	652:655	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	3	22	theme	decellularized	615:628	arg1	matrix					644:649	decellularized extracellular matrix	615:649	decellularized extracellular matrix (dECM)	615:656	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	1	23	theme	tissue	242:247	arg1	engineering					249:259	cartilage tissue engineering	232:259	cartilage tissue engineering	232:259	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	5	24	theme	mechanical	1015:1024	arg1	characteristics					1026:1040	mechanical characteristics	1015:1040	mechanical characteristics	1015:1040	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	3	25	theme	different	587:595	arg1	concentrations					597:610	different concentrations	587:610	different concentrations of decellularized extracellular matrix (dECM)	587:656	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	5	26	theme	further	1327:1333	arg1	studies					1343:1349	further in-vivo studies	1327:1349	further in-vivo studies	1327:1349	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	0	27	theme	manufacturing-based	12:30	arg1	3D					32:33	An additive manufacturing-based 3D	0:33	An additive manufacturing-based 3D	0:33	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	1	28	theme	Various	145:151	arg1	scaffolds					163:171	Various composite scaffolds	145:171	Various composite scaffolds with different fabrication techniques	145:209	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	5	29	theme	in-vivo	1335:1341	arg1	studies					1343:1349	further in-vivo studies	1327:1349	further in-vivo studies	1327:1349	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	4	30	theme	mesenchymal	729:739	arg1	cells					746:750	the adipose-derived mesenchymal stem cells	709:750	the adipose-derived mesenchymal stem cells	709:750	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	0	31	theme	poly	43:46	arg1	construct					101:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct	43:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration	43:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	5	32	theme	appropriate	1204:1214	arg1	features					1228:1235	appropriate biochemical features	1204:1235	appropriate biochemical features	1204:1235	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	5	33	dep	formulation	1259:1269	arg1	Alg-Sul					1293:1299	Alg-Sul	1293:1299	this new formulation based on PCL/dECM/Alg:Alg-Sul	1250:1299	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	4	34	theme	images	838:843	arg1	results					788:794	the results	784:794	the results of MTT assay, live/dead staining, and SEM images	784:843	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	2	35	theme	Alg-Sul	428:434	arg1	hydrogel					437:444	Alginate-Sulfate (Alg-Sul) hydrogel	410:444	Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly	410:544	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	5	36	theme	native	1152:1157	arg1	tissue					1175:1180	the native nasal cartilage tissue	1148:1180	the native nasal cartilage tissue	1148:1180	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	2	37	theme	poly	277:280	arg1	PCL					298:300	PCL	298:300	PCL	298:300	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	2	37	theme	poly	277:280	arg1	ɛ-caprolactone					282:295	poly ɛ-caprolactone	277:295	poly ɛ-caprolactone (PCL)	277:301	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	0	38	theme	sulfate/extracellular	72:92	arg1	construct					101:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct	43:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration	43:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	5	39	theme	nasal	1159:1163	arg1	tissue					1175:1180	the native nasal cartilage tissue	1148:1180	the native nasal cartilage tissue	1148:1180	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	3	40	theme	extracellular	630:642	arg1	dECM					652:655	dECM	652:655	dECM	652:655	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	3	40	theme	extracellular	630:642	arg1	matrix					644:649	decellularized extracellular matrix	615:649	decellularized extracellular matrix (dECM)	615:656	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	1	41	theme	composite	153:161	arg1	scaffolds					163:171	Various composite scaffolds	145:171	Various composite scaffolds with different fabrication techniques	145:209	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	0	42	theme	ɛ-caprolactone/alginate	48:70	arg1	construct					101:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct	43:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration	43:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	5	43	theme	cartilage	1165:1173	arg1	tissue					1175:1180	the native nasal cartilage tissue	1148:1180	the native nasal cartilage tissue	1148:1180	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	3	44	theme	matrix	644:649	arg1	concentrations					597:610	different concentrations	587:610	different concentrations of decellularized extracellular matrix (dECM)	587:656	Furthermore, to enhance chondrogenesis, different concentrations of decellularized extracellular matrix (dECM) were added to the hydrogel.					
35098649	4	45	theme	staining	820:827	arg1	images					838:843	MTT assay, live/dead staining, and SEM images	799:843	MTT assay, live/dead staining, and SEM images	799:843	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	4	46	theme	SEM	834:836	arg1	images					838:843	MTT assay, live/dead staining, and SEM images	799:843	MTT assay, live/dead staining, and SEM images	799:843	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	2	47	theme	prepared	360:367	arg1	scaffold					369:376	the prepared scaffold	356:376	the prepared scaffold	356:376	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	4	48	theme	cell	907:910	arg1	viability					912:920	cell viability	907:920	cell viability	907:920	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	5	49	theme	chondrogenic	1043:1054	arg1	differentiation					1056:1070	chondrogenic differentiation	1043:1070	chondrogenic differentiation	1043:1070	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	4	50	theme	MTT	799:801	arg1	assay					803:807	MTT assay	799:807	MTT assay	799:807	For cellular analyses, the adipose-derived mesenchymal stem cells were seeded on the hydrogel and the results of MTT assay, live/dead staining, and SEM images revealed that the scaffold with 1% dECM had better viscosity, cell viability, and proliferation.					
35098649	1	51	theme	different	178:186	arg1	techniques					200:209	different fabrication techniques	178:209	different fabrication techniques	178:209	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	5	52	theme	promising	1303:1311	arg1	candidate					1313:1321	a promising candidate	1301:1321	a promising candidate for further in-vivo studies	1301:1349	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	2	53	theme	glycosaminoglycans	518:535	arg1	structure					505:513	the structure	501:513	the structure of glycosaminoglycans	501:535	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	5	54	theme	%	994:994	arg1	dECM					996:999	1% dECM	993:999	1% dECM	993:999	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	5	54	theme	%	994:994	arg1	scaffold					983:990	the optimized scaffold	969:990	the optimized scaffold (1% dECM)	969:1000	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	1	55	theme	fabrication	188:198	arg1	techniques					200:209	different fabrication techniques	178:209	different fabrication techniques	178:209	Various composite scaffolds with different fabrication techniques have been applied in cartilage tissue engineering.					
35098649	5	56	theme	new	1255:1257	arg1	formulation					1259:1269	this new formulation	1250:1269	this new formulation based on PCL/dECM/Alg:Alg-Sul	1250:1299	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	0	57	theme	matrix	94:99	arg1	construct					101:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct	43:109	poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration	43:142	An additive manufacturing-based 3D printed poly ɛ-caprolactone/alginate sulfate/extracellular matrix construct for nasal cartilage regeneration.					
35098649	5	58	theme	mechanical	1123:1132	arg1	similarity					1134:1143	mechanical similarity	1123:1143	mechanical similarity to the native nasal cartilage tissue	1123:1180	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	2	59	theme	better	459:464	arg1	environment					477:487	a better biomimetic environment	457:487	a better biomimetic environment	457:487	In this study, poly ɛ-caprolactone (PCL) was printed by fused deposition modeling method, and the prepared scaffold was filled with Alginate (Alg): Alginate-Sulfate (Alg-Sul) hydrogel to provide a better biomimetic environment and emulate the structure of glycosaminoglycans properly.					
35098649	5	60	dep	showed	1116:1121	arg1	possessing					1193:1202	possessing	1193:1202	possessing appropriate biochemical features	1193:1235	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
35098649	5	60	dep	showed	1116:1121	arg1	makes					1244:1248	makes	1244:1248	makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies	1244:1349	The study was conducted on the optimized scaffold (1% dECM) to determine mechanical characteristics, chondrogenic differentiation, and results demonstrated that the scaffold showed mechanical similarity to the native nasal cartilage tissue along with possessing appropriate biochemical features, which makes this new formulation based on PCL/dECM/Alg:Alg-Sul a promising candidate for further in-vivo studies.					
36535358	7	0	theme	5 	958:959	arg1	%					960:960	%	960:960	%	960:960	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	9	1	from	immersion	1113:1121	arg1	water					1126:1130	water	1126:1130	water for 1 h	1126:1138	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	5	2	theme	contact	666:672	arg1	angle					674:678	The water contact angle	656:678	The water contact angle	656:678	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	0	3	theme	cellulose	83:91	arg1	nanofibres					93:102	cellulose nanofibres	83:102	cellulose nanofibres	83:102	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	10	4	theme	composite	1306:1314	arg1	films					1316:1320	the composite films	1302:1320	the composite films	1302:1320	These results indicate that the water-resistant properties of the composite films were significantly enhanced.					
36535358	1	5	theme	simple	158:163	arg1	route					165:169	a simple route	156:169	a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin	156:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	6	6	theme	nanocomposite	842:854	arg1	films					856:860	the nanocomposite films	838:860	the nanocomposite films	838:860	The mechanical properties of the nanocomposite films were significantly improved by the addition of LNPs.					
36535358	0	7	theme	lignin	108:113	arg1	nanoparticles					115:127	lignin nanoparticles	108:127	lignin nanoparticles	108:127	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	7	8	theme	DACNF-LNPs5	941:951	arg1	stress					931:936	The dry tensile stress	915:936	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs	915:965	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	3	9	with	nanoparticles	372:384	arg1	diameters					398:406	diameters	398:406	diameters between 50 and 150 nm	398:428	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	4	10	theme	LNPs	572:575	arg1	addition					560:567	The addition	556:567	The addition of LNPs	556:575	The addition of LNPs rendered the films with high ultraviolet-shielding and antioxidant properties.					
36535358	5	11	theme	pure	736:739	arg1	film					745:748	pure CNF film	736:748	pure CNF film	736:748	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	5	12	theme	composite	698:706	arg1	films					708:712	the composite films	694:712	the composite films	694:712	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	5	13	theme	water	660:664	arg1	angle					674:678	The water contact angle	656:678	The water contact angle	656:678	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	7	14	theme	tensile	923:929	arg1	stress					931:936	The dry tensile stress	915:936	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs	915:965	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	4	15	theme	high	601:604	arg1	properties					644:653	high ultraviolet-shielding and antioxidant properties	601:653	high ultraviolet-shielding and antioxidant properties	601:653	The addition of LNPs rendered the films with high ultraviolet-shielding and antioxidant properties.					
36535358	3	16	theme	DACNF-LNP	497:505	arg1	films					521:525	DACNF-LNP nanocomposite films	497:525	DACNF-LNP nanocomposite films	497:525	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	5	17	theme	transmission	773:784	arg1	WVTR					792:795	WVTR	792:795	WVTR	792:795	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	5	17	theme	transmission	773:784	arg1	rate					786:789	the water vapor transmission rate	757:789	the water vapor transmission rate (WVTR)	757:796	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	11	18	theme	food	1444:1447	arg1	packaging					1449:1457	food packaging	1444:1457	food packaging	1444:1457	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	3	19	theme	nanocomposite	507:519	arg1	films					521:525	DACNF-LNP nanocomposite films	497:525	DACNF-LNP nanocomposite films	497:525	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	3	20	theme	lignin	365:370	arg1	LNPs					387:390	LNPs	387:390	LNPs	387:390	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	3	20	theme	lignin	365:370	arg1	nanoparticles					372:384	lignin nanoparticles	365:384	lignin nanoparticles (LNPs) with diameters between 50 and 150 nm	365:428	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	6	21	theme	films	856:860	arg1	properties					824:833	The mechanical properties	809:833	The mechanical properties of the nanocomposite films	809:860	The mechanical properties of the nanocomposite films were significantly improved by the addition of LNPs.					
36535358	7	22	theme	dry	919:921	arg1	stress					931:936	The dry tensile stress	915:936	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs	915:965	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	0	23	theme	Bio-based	0:8	arg1	films					10:14	Bio-based films	0:14	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.	0:128	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	10	24	theme	films	1316:1320	arg1	properties					1288:1297	the water-resistant properties	1268:1297	the water-resistant properties of the composite films	1268:1320	These results indicate that the water-resistant properties of the composite films were significantly enhanced.					
36535358	0	25	theme	high	21:24	arg1	properties					67:76	high antioxidant and improved water-resistant properties	21:76	high antioxidant and improved water-resistant properties	21:76	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	9	26	theme	wet	1145:1147	arg1	times					1195:1199	times	1195:1199	times	1195:1199	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	26	theme	wet	1145:1147	arg1	strength					1157:1164	the wet tensile strength	1141:1164	the wet tensile strength of DACNF-LNPs5	1141:1179	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	4	27	theme	ultraviolet-shielding	606:626	arg1	properties					644:653	high ultraviolet-shielding and antioxidant properties	601:653	high ultraviolet-shielding and antioxidant properties	601:653	The addition of LNPs rendered the films with high ultraviolet-shielding and antioxidant properties.					
36535358	11	28	dep	green	1375:1379	arg1	bioresources					1395:1406	bioresources	1395:1406	bioresources	1395:1406	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	9	29	dep	times	1195:1199	arg1	higher					1201:1206	higher	1201:1206	higher	1201:1206	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	1	30	from	lignin	256:261	arg1	fabrication					179:189	the fabrication	175:189	the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin	175:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	1	30	from	lignin	256:261	arg1	films					214:218	bio-based composite films	194:218	bio-based composite films from cellulose nanofibres (CNF) and lignin	194:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	0	31	from	nanofibres	93:102	arg1	films					10:14	Bio-based films	0:14	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.	0:128	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	3	32	theme	condensation	533:544	arg1	reaction					546:553	a condensation reaction	531:553	a condensation reaction	531:553	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	1	33	theme	bio-based	194:202	arg1	films					214:218	bio-based composite films	194:218	bio-based composite films from cellulose nanofibres (CNF) and lignin	194:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	4	34	theme	antioxidant	632:642	arg1	properties					644:653	high ultraviolet-shielding and antioxidant properties	601:653	high ultraviolet-shielding and antioxidant properties	601:653	The addition of LNPs rendered the films with high ultraviolet-shielding and antioxidant properties.					
36535358	11	35	from	applications	1428:1439	arg1	packaging					1449:1457	food packaging	1444:1457	food packaging	1444:1457	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	11	35	from	applications	1428:1439	arg1	materials					1474:1482	biomedical materials	1463:1482	biomedical materials	1463:1482	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	1	36	theme	composite	204:212	arg1	films					214:218	bio-based composite films	194:218	bio-based composite films from cellulose nanofibres (CNF) and lignin	194:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	0	37	theme	antioxidant	26:36	arg1	properties					67:76	high antioxidant and improved water-resistant properties	21:76	high antioxidant and improved water-resistant properties	21:76	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	5	38	theme	water	761:765	arg1	WVTR					792:795	WVTR	792:795	WVTR	792:795	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	5	38	theme	water	761:765	arg1	rate					786:789	the water vapor transmission rate	757:789	the water vapor transmission rate (WVTR)	757:796	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	4	39	with	films	590:594	arg1	properties					644:653	high ultraviolet-shielding and antioxidant properties	601:653	high ultraviolet-shielding and antioxidant properties	601:653	The addition of LNPs rendered the films with high ultraviolet-shielding and antioxidant properties.					
36535358	1	40	theme	films	214:218	arg1	fabrication					179:189	the fabrication	175:189	the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin	175:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	0	41	theme	water-resistant	51:65	arg1	properties					67:76	high antioxidant and improved water-resistant properties	21:76	high antioxidant and improved water-resistant properties	21:76	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	7	42	with	stress	931:936	arg1	LNPs					962:965	5 % LNPs	958:965	5 % LNPs	958:965	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	1	43	from	nanofibres	235:244	arg1	fabrication					179:189	the fabrication	175:189	the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin	175:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	1	43	from	nanofibres	235:244	arg1	films					214:218	bio-based composite films	194:218	bio-based composite films from cellulose nanofibres (CNF) and lignin	194:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	9	44	theme	DACNF-LNPs5	1169:1179	arg1	times					1195:1199	times	1195:1199	times	1195:1199	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	44	theme	DACNF-LNPs5	1169:1179	arg1	strength					1157:1164	the wet tensile strength	1141:1164	the wet tensile strength of DACNF-LNPs5	1141:1179	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	10	45	theme	water-resistant	1272:1286	arg1	properties					1288:1297	the water-resistant properties	1268:1297	the water-resistant properties of the composite films	1268:1320	These results indicate that the water-resistant properties of the composite films were significantly enhanced.					
36535358	0	46	theme	improved	42:49	arg1	properties					67:76	high antioxidant and improved water-resistant properties	21:76	high antioxidant and improved water-resistant properties	21:76	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	3	47	theme	kraft	450:454	arg1	lignin					456:461	kraft lignin	450:461	kraft lignin	450:461	Subsequently, lignin nanoparticles (LNPs) with diameters between 50 and 150 nm were prepared using kraft lignin and mixed with DACNF to fabricate DACNF-LNP nanocomposite films via a condensation reaction.					
36535358	6	48	theme	mechanical	813:822	arg1	properties					824:833	The mechanical properties	809:833	The mechanical properties of the nanocomposite films	809:860	The mechanical properties of the nanocomposite films were significantly improved by the addition of LNPs.					
36535358	9	49	theme	31 MPa	1185:1190	arg1	times					1195:1199	times	1195:1199	times	1195:1199	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	49	theme	31 MPa	1185:1190	arg1	strength					1157:1164	the wet tensile strength	1141:1164	the wet tensile strength of DACNF-LNPs5	1141:1179	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	0	50	with	films	10:14	arg1	properties					67:76	high antioxidant and improved water-resistant properties	21:76	high antioxidant and improved water-resistant properties	21:76	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	2	51	theme	cellulose	321:329	arg1	DACNF					343:347	DACNF	343:347	DACNF	343:347	First, CNFs were periodate oxidised to obtain dialdehyde cellulose nanofibres (DACNF).					
36535358	2	51	theme	cellulose	321:329	arg1	nanofibres					331:340	dialdehyde cellulose nanofibres	310:340	dialdehyde cellulose nanofibres (DACNF)	310:348	First, CNFs were periodate oxidised to obtain dialdehyde cellulose nanofibres (DACNF).					
36535358	11	52	theme	potential	1418:1426	arg1	applications					1428:1439	potential applications	1418:1439	potential applications in food packaging and biomedical materials	1418:1482	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	6	53	theme	LNPs	909:912	arg1	addition					897:904	the addition	893:904	the addition of LNPs	893:912	The mechanical properties of the nanocomposite films were significantly improved by the addition of LNPs.					
36535358	0	54	from	nanoparticles	115:127	arg1	films					10:14	Bio-based films	0:14	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.	0:128	Bio-based films with high antioxidant and improved water-resistant properties from cellulose nanofibres and lignin nanoparticles.					
36535358	11	55	theme	biomedical	1463:1472	arg1	materials					1474:1482	biomedical materials	1463:1482	biomedical materials	1463:1482	The films prepared from green and renewable bioresources exhibited potential applications in food packaging and biomedical materials.					
36535358	2	56	theme	dialdehyde	310:319	arg1	DACNF					343:347	DACNF	343:347	DACNF	343:347	First, CNFs were periodate oxidised to obtain dialdehyde cellulose nanofibres (DACNF).					
36535358	2	56	theme	dialdehyde	310:319	arg1	nanofibres					331:340	dialdehyde cellulose nanofibres	310:340	dialdehyde cellulose nanofibres (DACNF)	310:348	First, CNFs were periodate oxidised to obtain dialdehyde cellulose nanofibres (DACNF).					
36535358	8	57	from	oxidised	1097:1104	arg1	that					1035:1038	that	1035:1038	that	1035:1038	It was also higher than that of CNF-LNPs5 (105 MPa), in which CNFs were not periodate oxidised.					
36535358	7	58	theme	%	960:960	arg1	LNPs					962:965	5 % LNPs	958:965	5 % LNPs	958:965	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
36535358	2	59	dep	oxidised	291:298	arg1	periodate					281:289	periodate	281:289	periodate	281:289	First, CNFs were periodate oxidised to obtain dialdehyde cellulose nanofibres (DACNF).					
36535358	1	60	theme	cellulose	225:233	arg1	nanofibres					235:244	cellulose nanofibres	225:244	cellulose nanofibres (CNF)	225:250	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	1	60	theme	cellulose	225:233	arg1	CNF					247:249	CNF	247:249	CNF	247:249	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	5	61	theme	CNF	741:743	arg1	film					745:748	pure CNF film	736:748	pure CNF film	736:748	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	9	62	theme	3	1193:1193	arg1	times					1195:1199	times	1195:1199	times	1195:1199	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	62	theme	3	1193:1193	arg1	strength					1157:1164	the wet tensile strength	1141:1164	the wet tensile strength of DACNF-LNPs5	1141:1179	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	63	theme	tensile	1149:1155	arg1	times					1195:1199	times	1195:1199	times	1195:1199	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	9	63	theme	tensile	1149:1155	arg1	strength					1157:1164	the wet tensile strength	1141:1164	the wet tensile strength of DACNF-LNPs5	1141:1179	After immersion in water for 1 h, the wet tensile strength of DACNF-LNPs5 was 31 MPa, 3 times higher than that of CNF-LNPs5 (7 MPa).					
36535358	1	64	from	fabrication	179:189	arg1	nanofibres					235:244	cellulose nanofibres	225:244	cellulose nanofibres (CNF)	225:250	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	1	64	from	fabrication	179:189	arg1	CNF					247:249	CNF	247:249	CNF	247:249	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	1	64	from	fabrication	179:189	arg1	lignin					256:261	lignin	256:261	lignin	256:261	In this study, we propose a simple route for the fabrication of bio-based composite films from cellulose nanofibres (CNF) and lignin.					
36535358	5	65	theme	vapor	767:771	arg1	WVTR					792:795	WVTR	792:795	WVTR	792:795	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	5	65	theme	vapor	767:771	arg1	rate					786:789	the water vapor transmission rate	757:789	the water vapor transmission rate (WVTR)	757:796	The water contact angle increased for the composite films compared with that of pure CNF film, while the water vapor transmission rate (WVTR) decreased.					
36535358	8	66	from	that	1035:1038	arg1	oxidised					1097:1104	oxidised	1097:1104	oxidised	1097:1104	It was also higher than that of CNF-LNPs5 (105 MPa), in which CNFs were not periodate oxidised.					
36535358	7	67	dep	164 MPa	1002:1008	arg1	to					999:1000	to	999:1000	to	999:1000	The dry tensile stress of DACNF-LNPs5 with 5 % LNPs significantly increased from 47 to 164 MPa.					
35398733	8	0	theme	antibacterial	1113:1125	arg1	activity					1127:1134	antibacterial activity	1113:1134	antibacterial activity against Gram-positive and Gram-negative bacterial strains	1113:1192	The composite membranes were also investigated for antibacterial activity against Gram-positive and Gram-negative bacterial strains.					
35398733	4	1	theme	TiO2	537:540	arg1	nanoparticles					542:554	TiO2 nanoparticles	537:554	TiO2 nanoparticles (NPs)	537:560	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	4	1	theme	TiO2	537:540	arg1	NPs					557:559	NPs	557:559	NPs	557:559	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	4	2	dep	in	591:592	arg1	situ					594:597	situ	594:597	situ	594:597	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	6	3	theme	m-2h-1	902:907	arg1	flux					882:885	a separation flux	869:885	a separation flux of 1498 ± 74 L m-2h-1	869:907	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	6	4	theme	L	900:900	arg1	m-2h-1					902:907	1498 ± 74 L m-2h-1	890:907	1498 ± 74 L m-2h-1	890:907	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	9	5	theme	next-generation	1236:1250	arg1	water					1366:1370	microbial contaminated water	1343:1370	microbial contaminated water	1343:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	5	theme	next-generation	1236:1250	arg1	membranes					1268:1276	next-generation multifunctional membranes	1236:1276	next-generation multifunctional membranes for wastewater treatment	1236:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	5	theme	next-generation	1236:1250	arg1	dyes					1334:1337	dyes	1334:1337	dyes	1334:1337	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	5	theme	next-generation	1236:1250	arg1	wastewater					1322:1331	wastewater	1322:1331	wastewater	1322:1331	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	3	6	theme	cellulose	393:401	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	6	7	theme	1498 ± 74	890:898	arg1	m-2h-1					902:907	1498 ± 74 L m-2h-1	890:907	1498 ± 74 L m-2h-1	890:907	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	4	8	theme	ZnO-NPs	609:615	arg1	growth					599:604	the in situ growth	587:604	the in situ growth of ZnO-NPs	587:615	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	0	9	theme	water	98:102	arg1	remediation					104:114	water remediation	98:114	water remediation	98:114	Fabrication of bacterial cellulose with TiO2-ZnO nanocomposites as a multifunctional membrane for water remediation.					
35398733	4	10	theme	BC	518:519	arg1	nanofibers					521:530	BC nanofibers	518:530	BC nanofibers with TiO2 nanoparticles (NPs)	518:560	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	5	11	theme	composite	622:630	arg1	membranes					632:640	The composite membranes	618:640	The composite membranes	618:640	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	8	12	theme	bacterial	1176:1184	arg1	strains					1186:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	The composite membranes were also investigated for antibacterial activity against Gram-positive and Gram-negative bacterial strains.					
35398733	1	13	dep	superoleophobic	145:159	arg1	SUS					162:164	SUS	162:164	SUS	162:164	Superhydrophilic/underwater superoleophobic (SUS) membrane technology has attracted extensive attention for water purification.					
35398733	1	14	theme	extensive	201:209	arg1	attention					211:219	extensive attention	201:219	extensive attention	201:219	Superhydrophilic/underwater superoleophobic (SUS) membrane technology has attracted extensive attention for water purification.					
35398733	3	15	theme	bacterial	383:391	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	6	16	theme	separation	871:880	arg1	flux					882:885	a separation flux	869:885	a separation flux of 1498 ± 74 L m-2h-1	869:907	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	5	17	theme	oil/water	649:657	arg1	separation					665:674	oil/water (o/w) separation	649:674	oil/water (o/w) separation	649:674	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	2	18	theme	complex	314:320	arg1	treatment					333:341	the complex wastewater treatment	310:341	the complex wastewater treatment	310:341	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	6	19	with	separate	833:840	arg1	flux					882:885	a separation flux	869:885	a separation flux of 1498 ± 74 L m-2h-1	869:907	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	6	19	with	separate	833:840	arg1	efficiency					923:932	high efficiency	918:932	high efficiency (99.25%)	918:941	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	6	19	with	separate	833:840	arg1	%					940:940	99.25%	935:940	99.25%	935:940	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	3	20	theme	based	408:412	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	5	21	theme	L	755:755	arg1	m-2h-1					757:762	8232.81 ± 212 L m-2h-1	741:762	8232.81 ± 212 L m-2h-1	741:762	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	7	22	with	light	1025:1029	arg1	efficiency					1043:1052	a high efficiency	1036:1052	a high efficiency (>92%)	1036:1059	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	7	22	with	light	1025:1029	arg1	%					1058:1058	>92%	1055:1058	>92%	1055:1058	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	3	23	theme	multifunctional	414:428	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	9	24	theme	microbial	1343:1351	arg1	water					1366:1370	microbial contaminated water	1343:1370	microbial contaminated water	1343:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	24	theme	microbial	1343:1351	arg1	membranes					1268:1276	next-generation multifunctional membranes	1236:1276	next-generation multifunctional membranes for wastewater treatment	1236:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	5	25	theme	o/w	660:662	arg1	separation					665:674	oil/water (o/w) separation	649:674	oil/water (o/w) separation	649:674	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	2	26	theme	big	354:356	arg1	fabrication					258:268	the fabrication	254:268	the fabrication of multifunctional membranes to satisfy the complex wastewater treatment	254:341	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	2	26	theme	big	354:356	arg1	challenge					358:366	a big challenge	352:366	a big challenge	352:366	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	3	27	theme	water	462:466	arg1	purification					468:479	water purification	462:479	water purification	462:479	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	3	28	theme	BC	404:405	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	8	29	theme	Gram-positive	1144:1156	arg1	strains					1186:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	The composite membranes were also investigated for antibacterial activity against Gram-positive and Gram-negative bacterial strains.					
35398733	9	30	dep	membranes	1268:1276	arg1	water					1366:1370	microbial contaminated water	1343:1370	microbial contaminated water	1343:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	30	dep	membranes	1268:1276	arg1	membranes					1268:1276	next-generation multifunctional membranes	1236:1276	next-generation multifunctional membranes for wastewater treatment	1236:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	30	dep	membranes	1268:1276	arg1	dyes					1334:1337	dyes	1334:1337	dyes	1334:1337	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	30	dep	membranes	1268:1276	arg1	wastewater					1322:1331	wastewater	1322:1331	wastewater	1322:1331	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	0	31	theme	bacterial	15:23	arg1	cellulose					25:33	bacterial cellulose	15:33	bacterial cellulose	15:33	Fabrication of bacterial cellulose with TiO2-ZnO nanocomposites as a multifunctional membrane for water remediation.					
35398733	4	32	theme	in	591:592	arg1	growth					599:604	the in situ growth	587:604	the in situ growth of ZnO-NPs	587:615	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	2	33	theme	wastewater	322:331	arg1	treatment					333:341	the complex wastewater treatment	310:341	the complex wastewater treatment	310:341	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	8	34	theme	composite	1066:1074	arg1	membranes					1076:1084	The composite membranes	1062:1084	The composite membranes	1062:1084	The composite membranes were also investigated for antibacterial activity against Gram-positive and Gram-negative bacterial strains.					
35398733	2	35	theme	multifunctional	273:287	arg1	membranes					289:297	multifunctional membranes	273:297	multifunctional membranes	273:297	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	1	36	theme	water	225:229	arg1	purification					231:242	water purification	225:242	water purification	225:242	Superhydrophilic/underwater superoleophobic (SUS) membrane technology has attracted extensive attention for water purification.					
35398733	9	37	theme	contaminated	1353:1364	arg1	water					1366:1370	microbial contaminated water	1343:1370	microbial contaminated water	1343:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	37	theme	contaminated	1353:1364	arg1	membranes					1268:1276	next-generation multifunctional membranes	1236:1276	next-generation multifunctional membranes for wastewater treatment	1236:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	5	38	theme	high	775:778	arg1	efficiency					791:800	a high separation efficiency	773:800	a high separation efficiency (>99.9%)	773:809	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	38	theme	high	775:778	arg1	%					808:808	>99.9%	803:808	>99.9%	803:808	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	7	39	theme	high	1038:1041	arg1	efficiency					1043:1052	a high efficiency	1036:1052	a high efficiency (>92%)	1036:1059	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	7	39	theme	high	1038:1041	arg1	%					1058:1058	>92%	1055:1058	>92%	1055:1058	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	6	40	theme	oil-in-water	842:853	arg1	emulsion					855:862	oil-in-water emulsion	842:862	oil-in-water emulsion	842:862	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	0	41	theme	cellulose	25:33	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of bacterial cellulose with TiO2-ZnO	0:47	Fabrication of bacterial cellulose with TiO2-ZnO nanocomposites as a multifunctional membrane for water remediation.					
35398733	7	42	theme	photocatalytic	987:1000	arg1	activity					1002:1009	photocatalytic activity	987:1009	photocatalytic activity	987:1009	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	5	43	theme	8232.81 ± 212	741:753	arg1	m-2h-1					757:762	8232.81 ± 212 L m-2h-1	741:762	8232.81 ± 212 L m-2h-1	741:762	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	3	44	theme	SUS	430:432	arg1	membranes					434:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	bacterial cellulose (BC) based multifunctional SUS membranes	383:442	In this work, bacterial cellulose (BC) based multifunctional SUS membranes were designed for water purification.					
35398733	5	45	theme	flux	728:731	arg1	rate					733:736	a flux rate	726:736	a flux rate of 8232.81 ± 212 L m-2h-1	726:762	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	46	theme	small	684:688	arg1	pressure					698:705	a small driving pressure	682:705	a small driving pressure (0.2-0.3 bar)	682:719	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	46	theme	small	684:688	arg1	0.2-0.3 bar					708:718	0.2-0.3 bar	708:718	0.2-0.3 bar	708:718	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	47	theme	m-2h-1	757:762	arg1	rate					733:736	a flux rate	726:736	a flux rate of 8232.81 ± 212 L m-2h-1	726:762	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	1	48	theme	superoleophobic	145:159	arg1	technology					176:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology	117:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology	117:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology has attracted extensive attention for water purification.					
35398733	6	49	theme	high	918:921	arg1	efficiency					923:932	high efficiency	918:932	high efficiency (99.25%)	918:941	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	6	49	theme	high	918:921	arg1	%					940:940	99.25%	935:940	99.25%	935:940	Membranes could also separate oil-in-water emulsion with a separation flux of 1498 ± 74 L m-2h-1 and with high efficiency (99.25%).					
35398733	5	50	theme	driving	690:696	arg1	pressure					698:705	a small driving pressure	682:705	a small driving pressure (0.2-0.3 bar)	682:719	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	50	theme	driving	690:696	arg1	0.2-0.3 bar					708:718	0.2-0.3 bar	708:718	0.2-0.3 bar	708:718	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	9	51	theme	multifunctional	1252:1266	arg1	water					1366:1370	microbial contaminated water	1343:1370	microbial contaminated water	1343:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	51	theme	multifunctional	1252:1266	arg1	membranes					1268:1276	next-generation multifunctional membranes	1236:1276	next-generation multifunctional membranes for wastewater treatment	1236:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	51	theme	multifunctional	1252:1266	arg1	dyes					1334:1337	dyes	1334:1337	dyes	1334:1337	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	51	theme	multifunctional	1252:1266	arg1	wastewater					1322:1331	wastewater	1322:1331	wastewater	1322:1331	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	9	52	theme	membranes	1268:1276	arg1	fabrication					1221:1231	the fabrication	1217:1231	the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water	1217:1370	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	0	53	with	Fabrication	0:10	arg1	TiO2-ZnO					40:47	TiO2-ZnO	40:47	TiO2-ZnO	40:47	Fabrication of bacterial cellulose with TiO2-ZnO nanocomposites as a multifunctional membrane for water remediation.					
35398733	7	54	theme	visible	1017:1023	arg1	light					1025:1029	visible light	1017:1029	visible light with a high efficiency (>92%)	1017:1059	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	8	55	theme	Gram-negative	1162:1174	arg1	strains					1186:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	Gram-positive and Gram-negative bacterial strains	1144:1192	The composite membranes were also investigated for antibacterial activity against Gram-positive and Gram-negative bacterial strains.					
35398733	0	56	theme	multifunctional	69:83	arg1	membrane					85:92	a multifunctional membrane	67:92	a multifunctional membrane for water remediation	67:114	Fabrication of bacterial cellulose with TiO2-ZnO nanocomposites as a multifunctional membrane for water remediation.					
35398733	9	57	theme	wastewater	1282:1291	arg1	treatment					1293:1301	wastewater treatment	1282:1301	wastewater treatment	1282:1301	This work may inspire the fabrication of next-generation multifunctional membranes for wastewater treatment, particularly oily wastewater, dyes and microbial contaminated water.					
35398733	7	58	theme	composite	958:966	arg1	membrane					968:975	the composite membrane	954:975	the composite membrane	954:975	Moreover, the composite membrane exhibited photocatalytic activity under visible light with a high efficiency (>92%).					
35398733	1	59	theme	membrane	167:174	arg1	technology					176:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology	117:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology	117:185	Superhydrophilic/underwater superoleophobic (SUS) membrane technology has attracted extensive attention for water purification.					
35398733	5	60	theme	separation	780:789	arg1	efficiency					791:800	a high separation efficiency	773:800	a high separation efficiency (>99.9%)	773:809	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	5	60	theme	separation	780:789	arg1	%					808:808	>99.9%	803:808	>99.9%	803:808	The composite membranes showed oil/water (o/w) separation under a small driving pressure (0.2-0.3 bar) with a flux rate of 8232.81 ± 212 L m-2h-1 and with a high separation efficiency (>99.9%).					
35398733	2	61	theme	membranes	289:297	arg1	fabrication					258:268	the fabrication	254:268	the fabrication of multifunctional membranes to satisfy the complex wastewater treatment	254:341	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	2	61	theme	membranes	289:297	arg1	challenge					358:366	a big challenge	352:366	a big challenge	352:366	However, the fabrication of multifunctional membranes to satisfy the complex wastewater treatment is still a big challenge.					
35398733	4	62	with	nanofibers	521:530	arg1	nanoparticles					542:554	TiO2 nanoparticles	537:554	TiO2 nanoparticles (NPs)	537:560	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
35398733	4	62	with	nanofibers	521:530	arg1	NPs					557:559	NPs	557:559	NPs	557:559	Membranes were prepared by blending BC nanofibers with TiO2 nanoparticles (NPs), and further modified by the in situ growth of ZnO-NPs.					
37298994	3	0	theme	TPS	650:652	arg1	compositions					654:665	TPS compositions	650:665	TPS compositions between 5 and 90 wt%	650:686	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	7	1	from	discrepancies	1297:1309	arg1	fingerprint					1314:1324	fingerprint	1314:1324	fingerprint	1314:1324	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	5	2	theme	weight	822:827	arg1	loss					829:832	a small weight loss	814:832	a small weight loss existing at intermediate degradation temperature between those of the two pristine components	814:926	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
37298994	1	3	theme	thermoplastic	250:262	arg1	starch					264:269	thermoplastic starch	250:269	thermoplastic starch (TPS)	250:275	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	3	theme	thermoplastic	250:262	arg1	TPS					272:274	TPS	272:274	TPS	272:274	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	6	4	dep	appearance	1187:1196	arg1	evolution					1198:1206	evolution	1198:1206	a different surface appearance evolution between the two series	1167:1229	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	6	5	with	morphology	1092:1101	arg1	inversion					1117:1125	a phase inversion	1109:1125	a phase inversion at around 80 wt% TPS	1109:1146	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	5	6	theme	pristine	908:915	arg1	components					917:926	the two pristine components	900:926	the two pristine components	900:926	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
37298994	7	7	from	interactions	1392:1403	arg1	TPS/EMAA-54Na					1408:1420	TPS/EMAA-54Na	1408:1420	TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer	1408:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	1	8	theme	starch	264:269	arg1	EMAA					327:330	EMAA	327:330	EMAA	327:330	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	8	theme	starch	264:269	arg1	copolymer					316:324	thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer	250:324	thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA)	250:331	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	5	9	theme	specific	936:943	arg1	interactions					945:956	specific interactions	936:956	specific interactions	936:956	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
37298994	7	10	theme	interactions	1392:1403	arg1	terms					1372:1376	terms	1372:1376	terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer	1372:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	6	11	from	TPS	1144:1146	arg1	inversion					1117:1125	a phase inversion	1109:1125	a phase inversion at around 80 wt% TPS	1109:1146	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	1	12	theme	ionomer	340:346	arg1	EMAA-54Na					354:362	EMAA-54Na	354:362	EMAA-54Na	354:362	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	12	theme	ionomer	340:346	arg1	form					348:351	its ionomer form	336:351	its ionomer form (EMAA-54Na)	336:363	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	7	13	theme	spectroscopy	1261:1272	arg1	analysis					1274:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	4	14	theme	main	716:719	arg1	losses					728:733	two main weight losses	712:733	two main weight losses	712:733	Thermogravimetry shows two main weight losses, indicating that TPS and the two copolymers are primarily immiscible.					
37298994	0	15	theme	ethylene-co-methacrylic	105:127	arg1	Poly					100:103	Poly	100:103	Poly(ethylene-co-methacrylic acid)	100:133	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	0	15	theme	ethylene-co-methacrylic	105:127	arg1	acid					129:132	ethylene-co-methacrylic acid	105:132	ethylene-co-methacrylic acid	105:132	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	6	16	theme	two-phase	1075:1083	arg1	morphology					1092:1101	a two-phase domain morphology	1073:1101	a two-phase domain morphology	1073:1101	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	0	17	theme	Thermogravimetric	0:16	arg1	Analysis					46:53	Thermogravimetric, Morphological and Infrared Analysis	0:53	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.	0:155	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	7	18	from	TPS/EMAA-54Na	1408:1420	arg1	terms					1372:1376	terms	1372:1376	terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer	1372:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	6	19	theme	surface	1179:1185	arg1	appearance					1187:1196	a different surface appearance	1167:1196	a different surface appearance evolution between the two series	1167:1229	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	6	20	theme	phase	1111:1115	arg1	inversion					1117:1125	a phase inversion	1109:1125	a phase inversion at around 80 wt% TPS	1109:1146	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	6	21	theme	electron	1007:1014	arg1	microscopy					1016:1025	scanning electron microscopy	998:1025	scanning electron microscopy	998:1025	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	2	22	theme	functional	408:417	arg1	groups					419:424	carboxylate functional groups	396:424	carboxylate functional groups of the ionomer	396:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	2	22	theme	functional	408:417	arg1	ionomer					433:439	the ionomer	429:439	the ionomer	429:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	6	23	theme	different	1169:1177	arg1	appearance					1187:1196	a different surface appearance	1167:1196	a different surface appearance evolution between the two series	1167:1229	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	7	24	theme	carboxylate	1471:1481	arg1	functions					1483:1491	carboxylate functions	1471:1491	carboxylate functions of the ionomer	1471:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	1	25	theme	thermal	183:189	arg1	properties					191:200	thermal properties	183:200	thermal properties	183:200	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	2	26	theme	carboxylate	396:406	arg1	groups					419:424	carboxylate functional groups	396:424	carboxylate functional groups of the ionomer	396:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	2	26	theme	carboxylate	396:406	arg1	ionomer					433:439	the ionomer	429:439	the ionomer	429:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	6	27	theme	%	1142:1142	arg1	TPS					1144:1146	around 80 wt% TPS	1130:1146	around 80 wt% TPS	1130:1146	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	6	28	theme	mesoscale	981:989	arg1	level					991:995	a mesoscale level	979:995	a mesoscale level	979:995	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	7	29	theme	infrared	1252:1259	arg1	analysis					1274:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	0	30	theme	Morphological	19:31	arg1	Analysis					46:53	Thermogravimetric, Morphological and Infrared Analysis	0:53	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.	0:155	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	1	31	theme	poly	281:284	arg1	EMAA					327:330	EMAA	327:330	EMAA	327:330	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	31	theme	poly	281:284	arg1	copolymer					316:324	thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer	250:324	thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA)	250:331	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	2	32	theme	materials	508:516	arg1	interface					487:495	the interface	483:495	the interface of the two materials	483:516	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	6	33	theme	thermogravimetry	1037:1052	arg1	results					1054:1060	thermogravimetry results	1037:1060	thermogravimetry results	1037:1060	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	3	34	dep	blends	571:576	arg1	blends					571:576	blends	571:576	blends (TPS/EMAA and TPS/EMAA-54Na)	571:605	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	3	34	dep	blends	571:576	arg1	TPS/EMAA-54Na					592:604	TPS/EMAA-54Na	592:604	TPS/EMAA-54Na	592:604	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	3	34	dep	blends	571:576	arg1	TPS/EMAA					579:586	TPS/EMAA	579:586	TPS/EMAA	579:586	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	3	35	theme	wt	684:685	arg1	%					686:686	5 and 90 wt%	675:686	5 and 90 wt%	675:686	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	0	36	theme	Ionomer	143:149	arg1	Form					151:154	Its Ionomer Form	139:154	Its Ionomer Form	139:154	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	2	37	from	intervene	446:454	arg1	compatibility					466:478	blends compatibility	459:478	blends compatibility at the interface of the two materials	459:516	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	6	38	theme	scanning	998:1005	arg1	microscopy					1016:1025	scanning electron microscopy	998:1025	scanning electron microscopy	998:1025	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	1	39	theme	structural	206:215	arg1	features					217:224	structural features	206:224	structural features	206:224	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	2	40	theme	ionomer	433:439	arg1	groups					419:424	carboxylate functional groups	396:424	carboxylate functional groups of the ionomer	396:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	2	40	theme	ionomer	433:439	arg1	ionomer					433:439	the ionomer	429:439	the ionomer	429:439	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	1	41	theme	ethylene-co-methacrylic	286:308	arg1	poly					281:284	poly	281:284	poly(ethylene-co-methacrylic acid)	281:314	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	41	theme	ethylene-co-methacrylic	286:308	arg1	acid					310:313	ethylene-co-methacrylic acid	286:313	ethylene-co-methacrylic acid	286:313	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	0	42	theme	Infrared	37:44	arg1	Analysis					46:53	Thermogravimetric, Morphological and Infrared Analysis	0:53	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.	0:155	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	2	43	from	compatibility	466:478	arg1	intervene					446:454	intervene	446:454	intervene	446:454	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	7	44	theme	blends	1352:1357	arg1	series					1342:1347	the two series	1334:1347	the two series	1334:1347	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	7	45	theme	Fourier-transformed	1232:1250	arg1	analysis					1274:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis	1232:1281	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	0	46	theme	Blends	58:63	arg1	Analysis					46:53	Thermogravimetric, Morphological and Infrared Analysis	0:53	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.	0:155	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	2	47	dep	investigate	380:390	arg1	impacts					531:537	impacts	531:537	impacts their properties	531:554	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	2	47	dep	investigate	380:390	arg1	form					441:444	form	441:444	form intervene in blends compatibility at the interface of the two materials	441:516	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	0	48	theme	Form	151:154	arg1	Analysis					46:53	Thermogravimetric, Morphological and Infrared Analysis	0:53	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.	0:155	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	7	49	theme	ionomer	1500:1506	arg1	functions					1483:1491	carboxylate functions	1471:1491	carboxylate functions of the ionomer	1471:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	6	50	theme	domain	1085:1090	arg1	morphology					1092:1101	a two-phase domain morphology	1073:1101	a two-phase domain morphology	1073:1101	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	6	51	theme	wt	1140:1141	arg1	TPS					1144:1146	around 80 wt% TPS	1130:1146	around 80 wt% TPS	1130:1146	At a mesoscale level, scanning electron microscopy confirmed thermogravimetry results and showed a two-phase domain morphology, with a phase inversion at around 80 wt% TPS, but also revealed a different surface appearance evolution between the two series.					
37298994	3	52	theme	internal	629:636	arg1	mixer					638:642	an internal mixer	626:642	an internal mixer	626:642	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	5	53	theme	intermediate	846:857	arg1	temperature					871:881	intermediate degradation temperature	846:881	intermediate degradation temperature	846:881	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
37298994	7	54	theme	additional	1381:1390	arg1	interactions					1392:1403	additional interactions	1381:1403	additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer	1381:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	4	55	theme	weight	721:726	arg1	losses					728:733	two main weight losses	712:733	two main weight losses	712:733	Thermogravimetry shows two main weight losses, indicating that TPS and the two copolymers are primarily immiscible.					
37298994	5	56	theme	degradation	859:869	arg1	temperature					871:881	intermediate degradation temperature	846:881	intermediate degradation temperature	846:881	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
37298994	1	57	theme	blends	229:234	arg1	properties					191:200	thermal properties	183:200	thermal properties	183:200	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	1	57	theme	blends	229:234	arg1	features					217:224	structural features	206:224	structural features	206:224	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	0	58	theme	Thermoplastic	75:87	arg1	Starch					89:94	Thermoplastic Starch	75:94	Thermoplastic Starch	75:94	Thermogravimetric, Morphological and Infrared Analysis of Blends Involving Thermoplastic Starch and Poly(ethylene-co-methacrylic acid) and Its Ionomer Form.					
37298994	2	59	from	interface	487:495	arg1	compatibility					466:478	blends compatibility	459:478	blends compatibility at the interface of the two materials	459:516	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	1	60	dep	properties	191:200	arg1	the					179:181	the	179:181	the	179:181	This study focuses on the thermal properties and structural features of blends consisting of thermoplastic starch (TPS) and poly(ethylene-co-methacrylic acid) copolymer (EMAA) or its ionomer form (EMAA-54Na).					
37298994	7	61	from	terms	1372:1376	arg1	TPS/EMAA-54Na					1408:1420	TPS/EMAA-54Na	1408:1420	TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer	1408:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	7	62	theme	supplementary	1438:1450	arg1	sodium					1452:1457	the supplementary sodium	1434:1457	the supplementary sodium neutralized carboxylate functions of the ionomer	1434:1506	Fourier-transformed infrared spectroscopy analysis also revealed discrepancies in fingerprint between the two series of blends, analysed in terms of additional interactions in TPS/EMAA-54Na coming from the supplementary sodium neutralized carboxylate functions of the ionomer.					
37298994	2	63	theme	blends	459:464	arg1	compatibility					466:478	blends compatibility	459:478	blends compatibility at the interface of the two materials	459:516	The aim is to investigate how carboxylate functional groups of the ionomer form intervene in blends compatibility at the interface of the two materials and how this impacts their properties.					
37298994	3	64	theme	blends	571:576	arg1	series					561:566	Two series	557:566	Two series of blends (TPS/EMAA and TPS/EMAA-54Na)	557:605	Two series of blends (TPS/EMAA and TPS/EMAA-54Na) were produced with an internal mixer, with TPS compositions between 5 and 90 wt%.					
37298994	5	65	theme	small	816:820	arg1	loss					829:832	a small weight loss	814:832	a small weight loss existing at intermediate degradation temperature between those of the two pristine components	814:926	However, a small weight loss existing at intermediate degradation temperature between those of the two pristine components reveals specific interactions at the interface.					
36263702	4	0	theme	hybrid	565:570	arg1	membranes					572:580	Inorganic hybrid membranes	555:580	Inorganic hybrid membranes with constant thickness	555:604	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	4	1	theme	sufficient	643:652	arg1	amount					654:659	a sufficient amount	641:659	a sufficient amount of sodium phosphate	641:679	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	4	1	theme	sufficient	643:652	arg1	phosphate					671:679	sodium phosphate	664:679	sodium phosphate	664:679	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	5	2	theme	membranes	726:734	arg1	characterization					702:717	The electrochemical characterization	682:717	The electrochemical characterization of the membranes	682:734	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	2	3	contain	containing	288:297	arg1	solution					279:286	a sodium alginate solution	261:286	a sodium alginate solution containing sodium phosphate in various compositions	261:338	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	3	contain	containing	288:297	arg2	phosphate					306:314	sodium phosphate	299:314	sodium phosphate	299:314	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	4	theme	various	319:325	arg1	compositions					327:338	various compositions	319:338	various compositions	319:338	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	3	5	theme	sodium	519:524	arg1	phosphate					526:534	sodium phosphate	519:534	sodium phosphate besides diffusion	519:552	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	1	6	theme	Systems	85:91	arg1	far-from-equilibrium					93:112	Systems far-from-equilibrium	85:112	Systems far-from-equilibrium	85:112	Systems far-from-equilibrium self-assemble into spatiotemporal structures.					
36263702	3	7	theme	viscoelastic	391:402	arg1	properties					404:413	The viscoelastic properties	387:413	The viscoelastic properties of the membranes developed	387:440	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	5	8	theme	cell	830:833	arg1	potential					835:843	the cell potential	826:843	the cell potential	826:843	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	5	9	theme	electrochemical	686:700	arg1	characterization					702:717	The electrochemical characterization	682:717	The electrochemical characterization of the membranes	682:734	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	5	10	theme	sodium	917:922	arg1	solution					933:940	the sodium alginate solution	913:940	the sodium alginate solution	913:940	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	0	11	theme	Flow-driven	0:10	arg1	synthesis					12:20	Flow-driven synthesis	0:20	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.	0:83	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	5	12	theme	alginate	924:931	arg1	solution					933:940	the sodium alginate solution	913:940	the sodium alginate solution	913:940	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	0	13	theme	calcium	25:31	arg1	gardens					76:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	1	14	theme	spatiotemporal	133:146	arg1	structures					148:157	spatiotemporal structures	133:157	spatiotemporal structures	133:157	Systems far-from-equilibrium self-assemble into spatiotemporal structures.					
36263702	3	15	theme	membranes	422:430	arg1	properties					404:413	The viscoelastic properties	387:413	The viscoelastic properties of the membranes developed	387:440	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	2	16	theme	gardens	213:219	arg1	formation					183:191	the formation	179:191	the formation of calcium alginate gardens along with their inorganic hybrids	179:254	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	4	17	with	membranes	572:580	arg1	thickness					596:604	constant thickness	587:604	constant thickness	587:604	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	5	18	theme	alkaline	882:889	arg1	phosphate					898:906	alkaline sodium phosphate	882:906	alkaline sodium phosphate into the sodium alginate solution	882:940	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	0	19	theme	alginate	51:58	arg1	gardens					76:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	5	20	theme	pH-gradient	775:785	arg1	force					762:766	the driving force	750:766	the driving force	750:766	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	5	20	theme	pH-gradient	775:785	arg1	developing					787:796	the pH-gradient developing	771:796	the pH-gradient developing along the two sides	771:816	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	2	21	theme	alginate	204:211	arg1	gardens					213:219	calcium alginate gardens	196:219	calcium alginate gardens along with their inorganic hybrids	196:254	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	22	theme	sodium	263:268	arg1	solution					279:286	a sodium alginate solution	261:286	a sodium alginate solution containing sodium phosphate in various compositions	261:338	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	5	23	theme	sodium	891:896	arg1	phosphate					898:906	alkaline sodium phosphate	882:906	alkaline sodium phosphate into the sodium alginate solution	882:940	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	0	24	theme	phosphate-calcium	33:49	arg1	gardens					76:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	3	25	theme	injection	464:472	arg1	rate					474:477	the injection rate	460:477	the injection rate	460:477	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	2	26	theme	calcium	196:202	arg1	gardens					213:219	calcium alginate gardens	196:219	calcium alginate gardens along with their inorganic hybrids	196:254	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	5	27	theme	phosphate	898:906	arg1	addition					870:877	the addition	866:877	the addition of alkaline sodium phosphate into the sodium alginate solution	866:940	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	0	28	theme	chemical	67:74	arg1	gardens					76:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	3	29	theme	phosphate	526:534	arg1	phosphate					526:534	sodium phosphate	519:534	sodium phosphate besides diffusion	519:552	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	3	29	theme	phosphate	526:534	arg1	amount					509:514	the amount	505:514	the amount of sodium phosphate besides diffusion	505:552	The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion.					
36263702	0	30	theme	hybrid	60:65	arg1	gardens					76:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	calcium phosphate-calcium alginate hybrid chemical gardens	25:82	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	2	31	theme	inorganic	238:246	arg1	hybrids					248:254	their inorganic hybrids	232:254	calcium alginate gardens along with their inorganic hybrids	196:254	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	32	theme	hybrids	248:254	arg1	formation					183:191	the formation	179:191	the formation of calcium alginate gardens along with their inorganic hybrids	179:254	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	4	33	theme	constant	587:594	arg1	thickness					596:604	constant thickness	587:604	constant thickness	587:604	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	5	34	theme	driving	754:760	arg1	force					762:766	the driving force	750:766	the driving force	750:766	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	5	34	theme	driving	754:760	arg1	developing					787:796	the pH-gradient developing	771:796	the pH-gradient developing along the two sides	771:816	The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.					
36263702	2	35	theme	sodium	299:304	arg1	phosphate					306:314	sodium phosphate	299:314	sodium phosphate	299:314	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	36	theme	chloride	367:374	arg1	reservoir					376:384	a calcium chloride reservoir	357:384	a calcium chloride reservoir	357:384	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	4	37	theme	Inorganic	555:563	arg1	membranes					572:580	Inorganic hybrid membranes	555:580	Inorganic hybrid membranes with constant thickness	555:604	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	2	38	theme	calcium	359:365	arg1	reservoir					376:384	a calcium chloride reservoir	357:384	a calcium chloride reservoir	357:384	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	2	39	dep	along	221:225	arg1	with					227:230	with	227:230	with	227:230	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	4	40	dep	amount	654:659	arg1	presence					629:636	presence	629:636	presence	629:636	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	4	40	dep	amount	654:659	arg1	the					625:627	the	625:627	the	625:627	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	4	41	theme	phosphate	671:679	arg1	amount					654:659	a sufficient amount	641:659	a sufficient amount of sodium phosphate	641:679	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	4	41	theme	phosphate	671:679	arg1	phosphate					671:679	sodium phosphate	664:679	sodium phosphate	664:679	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36263702	0	42	theme	gardens	76:82	arg1	synthesis					12:20	Flow-driven synthesis	0:20	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.	0:83	Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens.					
36263702	2	43	theme	alginate	270:277	arg1	solution					279:286	a sodium alginate solution	261:286	a sodium alginate solution containing sodium phosphate in various compositions	261:338	Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir.					
36263702	4	44	theme	sodium	664:669	arg1	phosphate					671:679	sodium phosphate	664:679	sodium phosphate	664:679	Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate.					
36122212	0	0	theme	mechanical	93:102	arg1	responsiveness					104:117	mechanical responsiveness	93:117	mechanical responsiveness	93:117	Rapid formation of uniformly layered materials by coupling reaction-diffusion processes with mechanical responsiveness.					
36122212	7	1	theme	rapid	1301:1305	arg1	patterning					1319:1328	rapid and uniform patterning	1301:1328	rapid and uniform patterning	1301:1328	This ensures rapid and uniform patterning.					
36122212	4	2	theme	band	923:926	arg1	spacing					928:934	the band spacing	919:934	the band spacing as the front advances	919:956	However, while diffusion is crucial to control patterning, it slows down transport of reactants to the front and results in a steady increase of the band spacing as the front advances.					
36122212	3	3	theme	propagating	581:591	arg1	front					602:606	A propagating reaction front	579:606	A propagating reaction front	579:606	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	5	4	from	process	1034:1040	arg1	hydrogels					1069:1077	mechanically responsive hydrogels	1045:1077	mechanically responsive hydrogels	1045:1077	Here, we circumvent these diffusive limitations by embedding the Liesegang process in mechanically responsive hydrogels.					
36122212	2	5	theme	patterned	558:566	arg1	materials					568:576	nonuniformly patterned materials	545:576	nonuniformly patterned materials	545:576	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	9	6	theme	banding	1708:1714	arg1	patterns					1716:1723	significantly smaller microscopic banding patterns	1674:1723	significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings	1674:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	6	theme	banding	1708:1714	arg1	gratings					1782:1789	self-organized diffraction gratings	1755:1789	self-organized diffraction gratings	1755:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	3	7	theme	reaction	593:600	arg1	front					602:606	A propagating reaction front	579:606	A propagating reaction front	579:606	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	1	8	theme	mechanical	288:297	arg1	properties					299:308	advanced optical, thermal, and mechanical properties	257:308	advanced optical, thermal, and mechanical properties	257:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	10	9	theme	materials	1958:1966	arg1	manufacturing					1923:1935	the manufacturing	1919:1935	the manufacturing of uniformly layered materials	1919:1966	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	5	10	theme	mechanically	1045:1056	arg1	hydrogels					1069:1077	mechanically responsive hydrogels	1045:1077	mechanically responsive hydrogels	1045:1077	Here, we circumvent these diffusive limitations by embedding the Liesegang process in mechanically responsive hydrogels.					
36122212	2	11	theme	attractive	342:351	arg1	systems					330:336	Reaction-diffusion systems	311:336	Reaction-diffusion systems	311:336	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	2	11	theme	attractive	342:351	arg1	candidates					353:362	attractive candidates	342:362	attractive candidates to this aim	342:374	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	9	12	theme	smaller	1688:1694	arg1	patterns					1716:1723	significantly smaller microscopic banding patterns	1674:1723	significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings	1674:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	12	theme	smaller	1688:1694	arg1	gratings					1782:1789	self-organized diffraction gratings	1755:1789	self-organized diffraction gratings	1755:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	4	13	theme	spacing	928:934	arg1	increase					907:914	a steady increase	898:914	a steady increase of the band spacing as the front advances	898:956	However, while diffusion is crucial to control patterning, it slows down transport of reactants to the front and results in a steady increase of the band spacing as the front advances.					
36122212	10	14	theme	inherent	1813:1820	arg1	limitations					1822:1832	the inherent limitations	1809:1832	the inherent limitations of diffusion	1809:1845	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	9	15	dep	generality	1547:1556	arg1	The					1543:1545	The	1543:1545	The	1543:1545	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	8	16	theme	5-cm	1377:1380	arg1	patterns					1399:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	4	17	theme	steady	900:905	arg1	increase					907:914	a steady increase	898:914	a steady increase of the band spacing as the front advances	898:956	However, while diffusion is crucial to control patterning, it slows down transport of reactants to the front and results in a steady increase of the band spacing as the front advances.					
36122212	6	18	theme	reaction	1110:1117	arg1	front					1119:1123	a moving reaction front	1101:1123	a moving reaction front	1101:1123	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	5	19	theme	Liesegang	1024:1032	arg1	process					1034:1040	the Liesegang process	1020:1040	the Liesegang process in mechanically responsive hydrogels	1020:1077	Here, we circumvent these diffusive limitations by embedding the Liesegang process in mechanically responsive hydrogels.					
36122212	6	20	theme	hydrogel	1129:1136	arg1	contraction					1138:1148	hydrogel contraction	1129:1148	hydrogel contraction	1129:1148	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	9	21	dep	patterns	1716:1723	arg1	d					1726:1726	d	1726:1726	d = 10 to 30 µm	1726:1740	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	8	22	theme	tunable	1426:1432	arg1	µm					1463:1464	d = 60 to 160 µm	1449:1464	d = 60 to 160 µm	1449:1464	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	22	theme	tunable	1426:1432	arg1	distance					1439:1446	tunable band distance	1426:1446	tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels	1426:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	9	23	theme	=	1728:1728	arg1	d					1726:1726	d	1726:1726	d = 10 to 30 µm	1726:1740	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	2	24	theme	Reaction-diffusion	311:328	arg1	systems					330:336	Reaction-diffusion systems	311:336	Reaction-diffusion systems	311:336	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	2	24	theme	Reaction-diffusion	311:328	arg1	candidates					353:362	attractive candidates	342:362	attractive candidates to this aim	342:374	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	9	25	theme	self-organized	1755:1768	arg1	patterns					1716:1723	significantly smaller microscopic banding patterns	1674:1723	significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings	1674:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	25	theme	self-organized	1755:1768	arg1	gratings					1782:1789	self-organized diffraction gratings	1755:1789	self-organized diffraction gratings	1755:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	8	26	dep	160	1459:1461	arg1	to					1456:1457	to	1456:1457	to	1456:1457	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	9	27	theme	precipitates	1658:1669	arg1	patterns					1646:1653	patterns	1646:1653	patterns of precipitates	1646:1669	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	1	28	theme	next	223:226	arg1	generation					228:237	the next generation	219:237	the next generation of materials with advanced optical, thermal, and mechanical properties	219:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	0	29	theme	Rapid	0:4	arg1	formation					6:14	Rapid formation	0:14	Rapid formation of uniformly layered materials by coupling reaction-diffusion	0:76	Rapid formation of uniformly layered materials by coupling reaction-diffusion processes with mechanical responsiveness.					
36122212	9	30	theme	diffraction	1770:1780	arg1	patterns					1716:1723	significantly smaller microscopic banding patterns	1674:1723	significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings	1674:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	30	theme	diffraction	1770:1780	arg1	gratings					1782:1789	self-organized diffraction gratings	1755:1789	self-organized diffraction gratings	1755:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	5	31	theme	diffusive	985:993	arg1	limitations					995:1005	these diffusive limitations	979:1005	these diffusive limitations	979:1005	Here, we circumvent these diffusive limitations by embedding the Liesegang process in mechanically responsive hydrogels.					
36122212	9	32	theme	strategy	1609:1616	arg1	applicability					1562:1574	applicability	1562:1574	applicability	1562:1574	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	32	theme	strategy	1609:1616	arg1	generality					1547:1556	generality	1547:1556	generality	1547:1556	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	33	dep	30	1736:1737	arg1	to					1733:1734	to	1733:1734	to	1733:1734	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	8	34	theme	dichromate	1477:1486	arg1	crystals					1488:1495	silver dichromate crystals	1470:1495	silver dichromate crystals	1470:1495	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	1	35	theme	Straightforward	120:134	arg1	pathways					150:157	Straightforward manufacturing pathways	120:157	Straightforward manufacturing pathways toward large-scale, uniformly layered composites	120:206	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	9	36	theme	microscopic	1696:1706	arg1	patterns					1716:1723	significantly smaller microscopic banding patterns	1674:1723	significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings	1674:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	9	36	theme	microscopic	1696:1706	arg1	gratings					1782:1789	self-organized diffraction gratings	1755:1789	self-organized diffraction gratings	1755:1789	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	2	37	theme	oriented	492:499	arg1	patches					501:507	randomly oriented patches	483:507	randomly oriented patches separated by defects	483:528	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	8	38	theme	band	1434:1437	arg1	µm					1463:1464	d = 60 to 160 µm	1449:1464	d = 60 to 160 µm	1449:1464	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	38	theme	band	1434:1437	arg1	distance					1439:1446	tunable band distance	1426:1446	tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels	1426:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	3	39	theme	reaction	716:723	arg1	front					725:729	a reaction front	714:729	a reaction front to produce layered precipitation patterns	714:771	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	1	40	theme	manufacturing	136:148	arg1	pathways					150:157	Straightforward manufacturing pathways	120:157	Straightforward manufacturing pathways toward large-scale, uniformly layered composites	120:206	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	1	41	theme	materials	242:250	arg1	generation					228:237	the next generation	219:237	the next generation of materials with advanced optical, thermal, and mechanical properties	219:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	0	42	theme	materials	37:45	arg1	formation					6:14	Rapid formation	0:14	Rapid formation of uniformly layered materials by coupling reaction-diffusion	0:76	Rapid formation of uniformly layered materials by coupling reaction-diffusion processes with mechanical responsiveness.					
36122212	8	43	theme	crystals	1488:1495	arg1	µm					1463:1464	d = 60 to 160 µm	1449:1464	d = 60 to 160 µm	1449:1464	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	43	theme	crystals	1488:1495	arg1	distance					1439:1446	tunable band distance	1426:1446	tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels	1426:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	3	44	theme	Liesegang	667:675	arg1	processes					677:685	Liesegang processes	667:685	Liesegang processes	667:685	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	6	45	theme	moving	1103:1108	arg1	front					1119:1123	a moving reaction front	1101:1123	a moving reaction front	1101:1123	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	0	46	theme	layered	29:35	arg1	materials					37:45	uniformly layered materials	19:45	uniformly layered materials	19:45	Rapid formation of uniformly layered materials by coupling reaction-diffusion processes with mechanical responsiveness.					
36122212	1	47	with	materials	242:250	arg1	properties					299:308	advanced optical, thermal, and mechanical properties	257:308	advanced optical, thermal, and mechanical properties	257:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	8	48	theme	gelatin-alginate	1515:1530	arg1	hydrogels					1532:1540	responsive gelatin-alginate hydrogels	1504:1540	responsive gelatin-alginate hydrogels	1504:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	49	dep	patterns	1399:1406	arg1	see					1368:1370	see	1368:1370	see text	1368:1375	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	1	50	theme	advanced	257:264	arg1	properties					299:308	advanced optical, thermal, and mechanical properties	257:308	advanced optical, thermal, and mechanical properties	257:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	0	51	theme	coupling	50:57	arg1	reaction-diffusion					59:76	coupling reaction-diffusion	50:76	coupling reaction-diffusion	50:76	Rapid formation of uniformly layered materials by coupling reaction-diffusion processes with mechanical responsiveness.					
36122212	4	52	theme	front	943:947	arg1	advances					949:956	the front advances	939:956	the front advances	939:956	However, while diffusion is crucial to control patterning, it slows down transport of reactants to the front and results in a steady increase of the band spacing as the front advances.					
36122212	8	53	theme	responsive	1504:1513	arg1	hydrogels					1532:1540	responsive gelatin-alginate hydrogels	1504:1540	responsive gelatin-alginate hydrogels	1504:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	10	54	theme	processes	1905:1913	arg1	potential					1873:1881	the potential	1869:1881	the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials	1869:1966	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	2	55	theme	layered	387:393	arg1	composites					395:404	layered composites	387:404	layered composites	387:404	Reaction-diffusion systems are attractive candidates to this aim, but while layered composites theoretically could spontaneously arise from reaction-diffusion, in practice randomly oriented patches separated by defects form, yielding nonuniformly patterned materials.					
36122212	10	56	theme	layered	1950:1956	arg1	materials					1958:1966	uniformly layered materials	1940:1966	uniformly layered materials	1940:1966	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	3	57	theme	layered	742:748	arg1	patterns					764:771	layered precipitation patterns	742:771	layered precipitation patterns	742:771	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	10	58	theme	reaction-diffusion	1886:1903	arg1	processes					1905:1913	reaction-diffusion processes	1886:1913	reaction-diffusion processes	1886:1913	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	6	59	theme	channel	1202:1208	arg1	formation					1162:1170	the formation	1158:1170	the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs	1158:1285	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	6	60	contain	carries	1229:1235	arg1	channel					1202:1208	a self-regulated transport channel	1175:1208	a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs	1175:1285	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	6	60	contain	carries	1229:1235	arg2	reactants					1237:1245	reactants	1237:1245	reactants toward the area where patterning occurs	1237:1285	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	3	61	theme	precipitation	750:762	arg1	patterns					764:771	layered precipitation patterns	742:771	layered precipitation patterns	742:771	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	4	62	theme	reactants	860:868	arg1	transport					847:855	transport	847:855	transport of reactants to the front	847:881	However, while diffusion is crucial to control patterning, it slows down transport of reactants to the front and results in a steady increase of the band spacing as the front advances.					
36122212	8	63	theme	large-scale	1345:1355	arg1	patterns					1399:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	1	64	theme	large-scale	166:176	arg1	composites					197:206	large-scale, uniformly layered composites	166:206	large-scale, uniformly layered composites	166:206	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	8	65	theme	=	1451:1451	arg1	µm					1463:1464	d = 60 to 160 µm	1449:1464	d = 60 to 160 µm	1449:1464	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	65	theme	=	1451:1451	arg1	distance					1439:1446	tunable band distance	1426:1446	tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels	1426:1540	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	1	66	theme	optical	266:272	arg1	properties					299:308	advanced optical, thermal, and mechanical properties	257:308	advanced optical, thermal, and mechanical properties	257:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	3	67	theme	such	620:623	arg1	patterning					636:645	such nonuniform patterning	620:645	such nonuniform patterning	620:645	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	1	68	dep	large-scale	166:176	arg1	layered					189:195	layered	189:195	layered	189:195	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	8	69	dep	see	1368:1370	arg1	[Formula					1358:1365	[Formula	1358:1365	[Formula	1358:1365	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	6	70	theme	self-regulated	1177:1190	arg1	channel					1202:1208	a self-regulated transport channel	1175:1208	a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs	1175:1285	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	6	71	theme	transport	1192:1200	arg1	channel					1202:1208	a self-regulated transport channel	1175:1208	a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs	1175:1285	The coupling between a moving reaction front and hydrogel contraction induces the formation of a self-regulated transport channel that ballistically carries reactants toward the area where patterning occurs.					
36122212	7	72	theme	uniform	1311:1317	arg1	patterning					1319:1328	rapid and uniform patterning	1301:1328	rapid and uniform patterning	1301:1328	This ensures rapid and uniform patterning.					
36122212	9	73	dep	=	1728:1728	arg1	µm					1739:1740	10 to 30 µm	1730:1740	10 to 30 µm	1730:1740	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	5	74	theme	responsive	1058:1067	arg1	hydrogels					1069:1077	mechanically responsive hydrogels	1045:1077	mechanically responsive hydrogels	1045:1077	Here, we circumvent these diffusive limitations by embedding the Liesegang process in mechanically responsive hydrogels.					
36122212	9	75	theme	mechanoreaction-diffusion	1583:1607	arg1	strategy					1609:1616	our mechanoreaction-diffusion strategy	1579:1616	our mechanoreaction-diffusion strategy	1579:1616	The generality and applicability of our mechanoreaction-diffusion strategy are demonstrated by forming patterns of precipitates in significantly smaller microscopic banding patterns (d = 10 to 30 µm) that act as self-organized diffraction gratings.					
36122212	8	76	theme	banding	1391:1397	arg1	patterns					1399:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	1	77	theme	thermal	275:281	arg1	properties					299:308	advanced optical, thermal, and mechanical properties	257:308	advanced optical, thermal, and mechanical properties	257:308	Straightforward manufacturing pathways toward large-scale, uniformly layered composites may enable the next generation of materials with advanced optical, thermal, and mechanical properties.					
36122212	10	78	theme	diffusion	1837:1845	arg1	limitations					1822:1832	the inherent limitations	1809:1832	the inherent limitations of diffusion	1809:1845	By circumventing the inherent limitations of diffusion, our strategy unlocks the potential of reaction-diffusion processes for the manufacturing of uniformly layered materials.					
36122212	3	79	theme	nonuniform	625:634	arg1	patterning					636:645	such nonuniform patterning	620:645	such nonuniform patterning	620:645	A propagating reaction front can prevent such nonuniform patterning, as is the case for Liesegang processes, in which diffusion drives a reaction front to produce layered precipitation patterns.					
36122212	8	80	theme	silver	1470:1475	arg1	crystals					1488:1495	silver dichromate crystals	1470:1495	silver dichromate crystals	1470:1495	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
36122212	8	81	theme	uniform	1383:1389	arg1	patterns					1399:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	large-scale ([Formula: see text]5-cm) uniform banding patterns	1345:1406	Specifically, large-scale ([Formula: see text]5-cm) uniform banding patterns are produced with tunable band distance (d = 60 to 160 µm) of silver dichromate crystals inside responsive gelatin-alginate hydrogels.					
35093432	0	0	theme	matrix	98:103	arg1	nanospheres					133:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres	75:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration	75:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	5	1	theme	wound	1132:1136	arg1	dehiscence					1138:1147	wound dehiscence	1132:1147	wound dehiscence	1132:1147	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	1	2	with	membranes	198:206	arg1	signals					232:238	regenerative signals	219:238	regenerative signals	219:238	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	1	2	with	membranes	198:206	arg1	topography					256:265	nanofibrous topography	244:265	nanofibrous topography	244:265	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	3	3	theme	barrier	757:763	arg1	membrane					765:772	barrier membrane	757:772	barrier membrane	757:772	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	7	4	theme	wound	1461:1465	arg1	healing					1467:1473	wound healing	1461:1473	wound healing	1461:1473	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	0	5	theme	enamel	91:96	arg1	matrix					98:103	enamel matrix	91:103	enamel matrix	91:103	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	7	6	with	FGM	1368:1370	arg1	composites					1438:1447	CE-PD nanofibrous composites	1420:1447	CE-PD nanofibrous composites	1420:1447	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	7	6	with	FGM	1368:1370	arg1	PD					1377:1378	PD	1377:1378	PD reduced early tissue breakdown	1377:1409	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	7	7	theme	advantageous	1526:1537	arg1	strategy					1539:1546	an advantageous strategy	1523:1546	an advantageous strategy for ARR	1523:1554	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	6	8	with	FGM	1260:1262	arg1	CE-PD					1269:1273	CE-PD	1269:1273	CE-PD	1269:1273	FGM with CE-PD revealed significantly greater new bone formation and defect fill at 4 weeks.					
35093432	3	9	theme	experimental	859:870	arg1	defects					887:893	experimental alveolar ridge defects	859:893	experimental alveolar ridge defects in rats	859:901	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	0	10	theme	chitosan	124:131	arg1	nanospheres					133:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres	75:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration	75:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	7	11	theme	CE-PD	1420:1424	arg1	composites					1438:1447	CE-PD nanofibrous composites	1420:1447	CE-PD nanofibrous composites	1420:1447	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	0	12	theme	derivatives-loaded	105:122	arg1	nanospheres					133:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres	75:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration	75:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	3	13	theme	membrane	765:772	arg1	surfaces					745:752	the surfaces	741:752	the surfaces of barrier membrane	741:772	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	7	14	theme	nanofibrous	1426:1436	arg1	composites					1438:1447	CE-PD nanofibrous composites	1420:1447	CE-PD nanofibrous composites	1420:1447	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	4	15	contain	had	929:931	arg2	capability					954:963	potent antibacterial capability	933:963	potent antibacterial capability	933:963	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	4	15	contain	had	929:931	arg1	PD					926:927	PD	926:927	PD	926:927	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	7	16	theme	tissue	1394:1399	arg1	breakdown					1401:1409	early tissue breakdown	1388:1409	early tissue breakdown	1388:1409	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	5	17	with	FGM	1074:1076	arg1	PD					1083:1084	PD	1083:1084	PD	1083:1084	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	3	18	theme	PDLLA	604:608	arg1	PD					622:623	PD	622:623	PD	622:623	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	18	theme	PDLLA	604:608	arg1	nanofibers					610:619	Doxycycline-loaded PDLLA nanofibers	585:619	Doxycycline-loaded PDLLA nanofibers (PD)	585:624	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	2	19	theme	doxycycline-enamel	424:441	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	4	20	theme	sustained	984:992	arg1	release					994:1000	sustained release	984:1000	sustained release of EMD	984:1007	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	5	21	from	1 week	1252:1257	arg1	surface					1241:1247	the inner surface	1231:1247	the inner surface at 1 week	1231:1257	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	2	22	theme	differentiation	537:551	arg1	signals					553:559	anti-inflammation and differentiation signals	515:559	anti-inflammation and differentiation signals	515:559	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	5	23	from	FGM	1074:1076	arg1	surface					1099:1105	the outer surface	1089:1105	the outer surface	1089:1105	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	3	24	theme	EMD-loaded	627:636	arg1	CE					660:661	CE	660:661	CE	660:661	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	24	theme	EMD-loaded	627:636	arg1	nanospheres					647:657	EMD-loaded chitosan nanospheres	627:657	EMD-loaded chitosan nanospheres (CE)	627:662	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	5	25	theme	Cbfa1	1174:1178	arg1	upregulation					1180:1191	Cbfa1 upregulation	1174:1191	Cbfa1 upregulation	1174:1191	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	2	26	theme	composites	479:488	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	3	27	theme	chitosan	638:645	arg1	CE					660:661	CE	660:661	CE	660:661	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	27	theme	chitosan	638:645	arg1	nanospheres					647:657	EMD-loaded chitosan nanospheres	627:657	EMD-loaded chitosan nanospheres (CE)	627:662	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	5	28	from	CE-PD	1222:1226	arg1	surface					1241:1247	the inner surface	1231:1247	the inner surface at 1 week	1231:1257	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	1	29	theme	regenerative	219:230	arg1	signals					232:238	regenerative signals	219:238	regenerative signals	219:238	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	2	30	theme	nanofibrous	467:477	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	0	31	theme	ridge	158:162	arg1	regeneration					164:175	alveolar ridge regeneration	149:175	alveolar ridge regeneration	149:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	3	32	from	defects	887:893	arg1	rats					898:901	rats	898:901	rats	898:901	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	2	33	theme	EMD	462:464	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	0	34	theme	membrane	20:27	arg1	deposited					29:37	membrane deposited	20:37	membrane deposited	20:37	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	0	35	theme	alveolar	149:156	arg1	regeneration					164:175	alveolar ridge regeneration	149:175	alveolar ridge regeneration	149:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	7	36	theme	early	1388:1392	arg1	breakdown					1401:1409	early tissue breakdown	1388:1409	early tissue breakdown	1388:1409	In conclusion, FGM with PD reduced early tissue breakdown and with CE-PD nanofibrous composites accelerated wound healing and facilitated osteogenesis, and thus could be an advantageous strategy for ARR.					
35093432	0	37	theme	PDLLA	44:48	arg1	nanofibers					50:59	PDLLA nanofibers	44:59	PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration	44:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	6	38	theme	defect	1329:1334	arg1	fill					1336:1339	defect fill	1329:1339	defect fill	1329:1339	FGM with CE-PD revealed significantly greater new bone formation and defect fill at 4 weeks.					
35093432	1	39	theme	nanofibrous	244:254	arg1	topography					256:265	nanofibrous topography	244:265	nanofibrous topography	244:265	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	2	40	theme	novel	409:413	arg1	FGM					415:417	a novel FGM	407:417	a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	407:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	2	41	theme	derivative	450:459	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	2	42	theme	anti-inflammation	515:531	arg1	signals					553:559	anti-inflammation and differentiation signals	515:559	anti-inflammation and differentiation signals	515:559	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	5	43	theme	inner	1235:1239	arg1	surface					1241:1247	the inner surface	1231:1247	the inner surface at 1 week	1231:1257	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	2	44	theme	matrix	443:448	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	1	45	theme	alveolar	351:358	arg1	ARR					380:382	ARR	380:382	ARR	380:382	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	1	45	theme	alveolar	351:358	arg1	regeneration					366:377	alveolar ridge regeneration	351:377	alveolar ridge regeneration (ARR)	351:383	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	5	46	theme	outer	1093:1097	arg1	surface					1099:1105	the outer surface	1089:1105	the outer surface	1089:1105	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	5	47	theme	alveolar	1050:1057	arg1	defects					1065:1071	the alveolar ridge defects	1046:1071	the alveolar ridge defects	1046:1071	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	6	48	theme	new	1306:1308	arg1	formation					1315:1323	significantly greater new bone formation	1284:1323	significantly greater new bone formation	1284:1323	FGM with CE-PD revealed significantly greater new bone formation and defect fill at 4 weeks.					
35093432	1	49	theme	ridge	360:364	arg1	ARR					380:382	ARR	380:382	ARR	380:382	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	1	49	theme	ridge	360:364	arg1	regeneration					366:377	alveolar ridge regeneration	351:377	alveolar ridge regeneration (ARR)	351:383	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	6	50	theme	bone	1310:1313	arg1	formation					1315:1323	significantly greater new bone formation	1284:1323	significantly greater new bone formation	1284:1323	FGM with CE-PD revealed significantly greater new bone formation and defect fill at 4 weeks.					
35093432	5	51	theme	ridge	1059:1063	arg1	defects					1065:1071	the alveolar ridge defects	1046:1071	the alveolar ridge defects	1046:1071	In the alveolar ridge defects, FGM with PD on the outer surface downregulated MMP-8, and wound dehiscence was further reduced with Cbfa1 upregulation in those treated by FGM with CE-PD on the inner surface at 1 week.					
35093432	1	52	theme	regeneration	366:377	arg1	outcome					340:346	the outcome	336:346	the outcome of alveolar ridge regeneration (ARR)	336:383	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	4	53	theme	potent	933:938	arg1	capability					954:963	potent antibacterial capability	933:963	potent antibacterial capability	933:963	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	3	54	theme	CE-embedded	669:679	arg1	CE-PD					685:689	CE-PD	685:689	CE-PD	685:689	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	54	theme	CE-embedded	669:679	arg1	PD					681:682	CE-embedded PD	669:682	CE-embedded PD (CE-PD)	669:690	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	6	55	theme	greater	1298:1304	arg1	formation					1315:1323	significantly greater new bone formation	1284:1323	significantly greater new bone formation	1284:1323	FGM with CE-PD revealed significantly greater new bone formation and defect fill at 4 weeks.					
35093432	3	56	theme	Doxycycline-loaded	585:602	arg1	PD					622:623	PD	622:623	PD	622:623	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	56	theme	Doxycycline-loaded	585:602	arg1	nanofibers					610:619	Doxycycline-loaded PDLLA nanofibers	585:619	Doxycycline-loaded PDLLA nanofibers (PD)	585:624	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	3	57	theme	alveolar	872:879	arg1	defects					887:893	experimental alveolar ridge defects	859:893	experimental alveolar ridge defects in rats	859:901	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	4	58	theme	antibacterial	940:952	arg1	capability					954:963	potent antibacterial capability	933:963	potent antibacterial capability	933:963	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	4	59	theme	EMD	1005:1007	arg1	release					994:1000	sustained release	984:1000	sustained release of EMD	984:1007	Results revealed that PD had potent antibacterial capability, and CE-PD allowed sustained release of EMD to promote osteogenesis in vitro.					
35093432	3	60	theme	ridge	881:885	arg1	defects					887:893	experimental alveolar ridge defects	859:893	experimental alveolar ridge defects in rats	859:901	Doxycycline-loaded PDLLA nanofibers (PD), EMD-loaded chitosan nanospheres (CE), and CE-embedded PD (CE-PD) were fabricated by electrospinning, deposited on the surfaces of barrier membrane to develop a FGM, and the efficacy was validated by delivering the FGM to regenerate experimental alveolar ridge defects in rats.					
35093432	1	61	theme	native	281:286	arg1	matrix					302:307	the native extracellular matrix	277:307	the native extracellular matrix	277:307	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	0	62	theme	doxycycline	75:85	arg1	nanospheres					133:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres	75:143	doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration	75:175	Functionally graded membrane deposited with PDLLA nanofibers encapsulating doxycycline and enamel matrix derivatives-loaded chitosan nanospheres for alveolar ridge regeneration.					
35093432	2	63	with	FGM	415:417	arg1	deposition					490:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition	424:499	doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR	424:582	This study developed a novel FGM with doxycycline-enamel matrix derivative (EMD) nanofibrous composites deposition to coordinate anti-inflammation and differentiation signals, thus facilitating ARR.					
35093432	1	64	theme	graded	191:196	arg1	FGM					209:211	FGM	209:211	FGM	209:211	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	1	64	theme	graded	191:196	arg1	membranes					198:206	Functionally graded membranes	178:206	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix	178:307	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
35093432	1	65	theme	extracellular	288:300	arg1	matrix					302:307	the native extracellular matrix	277:307	the native extracellular matrix	277:307	Functionally graded membranes (FGM) with regenerative signals and nanofibrous topography mimicking the native extracellular matrix have been shown to improve the outcome of alveolar ridge regeneration (ARR).					
36076310	0	0	theme	predicted	98:106	arg1	modifier					115:122	a computationally predicted chiral modifier	80:122	a computationally predicted chiral modifier	80:122	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	5	1	theme	chiral	899:904	arg1	nanotubes					925:933	chiral single-wall carbon nanotubes	899:933	chiral single-wall carbon nanotubes	899:933	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	7	2	theme	good	1146:1149	arg1	power					1162:1166	good predictive power	1146:1166	good predictive power	1146:1166	The suggested approach also showed good predictive power in application to enantioselective chromatography, which further validates its general applicability.					
36076310	5	3	theme	carbon	918:923	arg1	nanotubes					925:933	chiral single-wall carbon nanotubes	899:933	chiral single-wall carbon nanotubes	899:933	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	5	4	theme	chiral	938:943	arg1	modifiers					945:953	chiral modifiers	938:953	chiral modifiers	938:953	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	7	5	theme	predictive	1151:1160	arg1	power					1162:1166	good predictive power	1146:1166	good predictive power	1146:1166	The suggested approach also showed good predictive power in application to enantioselective chromatography, which further validates its general applicability.					
36076310	1	6	theme	simplest	166:173	arg1	strategies					192:201	the simplest and most popular strategies	162:201	the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media	162:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	4	7	theme	adsorption	783:792	arg1	ΔEads					804:808	ΔEads	804:808	ΔEads	804:808	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	7	theme	adsorption	783:792	arg1	energies					794:801	the corresponding adsorption energies	765:801	the corresponding adsorption energies (ΔEads )	765:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	0	8	theme	chiral	108:113	arg1	modifier					115:122	a computationally predicted chiral modifier	80:122	a computationally predicted chiral modifier	80:122	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	4	9	theme	corresponding	769:781	arg1	ΔEads					804:808	ΔEads	804:808	ΔEads	804:808	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	9	theme	corresponding	769:781	arg1	energies					794:801	the corresponding adsorption energies	765:801	the corresponding adsorption energies (ΔEads )	765:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	3	10	theme	chiral	548:553	arg1	modifier					555:562	a chiral modifier	546:562	a chiral modifier for preparing highly enantioselective sensors	546:608	We suggest a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors.					
36076310	4	11	from	adsorption	686:695	arg1	modifiers					730:738	chiral modifiers	723:738	chiral modifiers	723:738	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	11	from	adsorption	686:695	arg1	comparison					751:760	the comparison	747:760	the comparison of the corresponding adsorption energies (ΔEads )	747:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	3	12	theme	novel	495:499	arg1	approach					501:508	a novel approach	493:508	a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors	493:608	We suggest a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors.					
36076310	7	13	theme	suggested	1115:1123	arg1	approach					1125:1132	The suggested approach	1111:1132	The suggested approach	1111:1132	The suggested approach also showed good predictive power in application to enantioselective chromatography, which further validates its general applicability.					
36076310	3	14	theme	quality	535:541	arg1	prediction					517:526	the prediction	513:526	the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors	513:608	We suggest a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors.					
36076310	4	15	theme	adsorption	686:695	arg1	modeling					670:677	the molecular mechanics modeling	646:677	the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	646:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	5	16	theme	nanotubes	925:933	arg1	range					967:971	a wide range	960:971	a wide range of chiral analytes	960:990	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	5	16	theme	nanotubes	925:933	arg1	example					870:876	the example	866:876	the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers	866:953	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	4	17	theme	energies	794:801	arg1	comparison					751:760	the comparison	747:760	the comparison of the corresponding adsorption energies (ΔEads )	747:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	2	18	theme	key	407:409	arg1	factors					411:417	the key factors	403:417	the key factors for the creation of enantioselectivity to a specified analyte	403:479	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	2	18	theme	key	407:409	arg1	structure					366:374	structure	366:374	structure	366:374	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	2	18	theme	key	407:409	arg1	type					357:360	type	357:360	type	357:360	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	2	19	theme	specified	463:471	arg1	analyte					473:479	a specified analyte	461:479	a specified analyte	461:479	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	1	20	from	discrimination	296:309	arg1	media					346:350	various media	338:350	various media	338:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	4	21	from	modeling	670:677	arg1	modifiers					730:738	chiral modifiers	723:738	chiral modifiers	723:738	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	21	from	modeling	670:677	arg1	comparison					751:760	the comparison	747:760	the comparison of the corresponding adsorption energies (ΔEads )	747:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	1	22	theme	popular	184:190	arg1	strategies					192:201	the simplest and most popular strategies	162:201	the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media	162:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	0	23	theme	Rational	0:7	arg1	design					9:14	Rational design	0:14	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.	0:123	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	4	24	from	comparison	751:760	arg1	modeling					670:677	the molecular mechanics modeling	646:677	the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	646:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	5	25	theme	single-wall	906:916	arg1	nanotubes					925:933	chiral single-wall carbon nanotubes	899:933	chiral single-wall carbon nanotubes	899:933	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	7	26	theme	enantioselective	1186:1201	arg1	chromatography					1203:1216	enantioselective chromatography	1186:1216	enantioselective chromatography	1186:1216	The suggested approach also showed good predictive power in application to enantioselective chromatography, which further validates its general applicability.					
36076310	1	27	from	analysis	283:290	arg1	media					346:350	various media	338:350	various media	338:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	3	28	theme	modifier	555:562	arg1	quality					535:541	the quality	531:541	the quality of a chiral modifier for preparing highly enantioselective sensors	531:608	We suggest a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors.					
36076310	2	29	theme	enantioselectivity	439:456	arg1	creation					427:434	the creation	423:434	the creation of enantioselectivity to a specified analyte	423:479	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	1	30	theme	enantiomerical	314:327	arg1	drugs					329:333	enantiomerical drugs	314:333	enantiomerical drugs	314:333	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	5	31	theme	analytes	983:990	arg1	range					967:971	a wide range	960:971	a wide range of chiral analytes	960:990	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	5	31	theme	analytes	983:990	arg1	example					870:876	the example	866:876	the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers	866:953	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	4	32	theme	enantiomers	708:718	arg1	adsorption					686:695	the adsorption	682:695	the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	682:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	33	theme	analyte	700:706	arg1	enantiomers					708:718	analyte enantiomers	700:718	analyte enantiomers	700:718	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	0	34	theme	composite	43:51	arg1	sensors					66:72	highly enantioselective composite voltammetric sensors	19:72	highly enantioselective composite voltammetric sensors	19:72	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	1	35	theme	drugs	329:333	arg1	discrimination					296:309	discrimination	296:309	discrimination	296:309	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	1	35	theme	drugs	329:333	arg1	analysis					283:290	analysis	283:290	analysis	283:290	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	4	36	theme	mechanics	660:668	arg1	modeling					670:677	the molecular mechanics modeling	646:677	the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	646:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	1	37	theme	enantioselective	220:235	arg1	sensors					250:256	enantioselective voltammetric sensors	220:256	enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media	220:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	0	38	theme	enantioselective	26:41	arg1	sensors					66:72	highly enantioselective composite voltammetric sensors	19:72	highly enantioselective composite voltammetric sensors	19:72	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	5	39	theme	cyclodextrins	881:893	arg1	range					967:971	a wide range	960:971	a wide range of chiral analytes	960:990	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	5	39	theme	cyclodextrins	881:893	arg1	example					870:876	the example	866:876	the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers	866:953	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	1	40	theme	voltammetric	237:248	arg1	sensors					250:256	enantioselective voltammetric sensors	220:256	enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media	220:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	0	41	theme	sensors	66:72	arg1	design					9:14	Rational design	0:14	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.	0:123	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	1	42	theme	various	338:344	arg1	media					346:350	various media	338:350	various media	338:350	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	3	43	theme	enantioselective	585:600	arg1	sensors					602:608	highly enantioselective sensors	578:608	highly enantioselective sensors	578:608	We suggest a novel approach to the prediction of the quality of a chiral modifier for preparing highly enantioselective sensors.					
36076310	0	44	theme	voltammetric	53:64	arg1	sensors					66:72	highly enantioselective composite voltammetric sensors	19:72	highly enantioselective composite voltammetric sensors	19:72	Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier.					
36076310	1	45	dep	analysis	283:290	arg1	the					279:281	the	279:281	the	279:281	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	7	46	theme	general	1247:1253	arg1	applicability					1255:1267	its general applicability	1243:1267	its general applicability	1243:1267	The suggested approach also showed good predictive power in application to enantioselective chromatography, which further validates its general applicability.					
36076310	4	47	theme	chiral	723:728	arg1	modifiers					730:738	chiral modifiers	723:738	chiral modifiers	723:738	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	1	48	theme	chiral	136:141	arg1	modifiers					143:151	chiral modifiers	136:151	chiral modifiers	136:151	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	5	49	theme	wide	962:965	arg1	range					967:971	a wide range	960:971	a wide range of chiral analytes	960:990	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	1	50	theme	modifiers	143:151	arg1	use					129:131	The use	125:131	The use of chiral modifiers	125:151	The use of chiral modifiers is among the simplest and most popular strategies for synthesizing enantioselective voltammetric sensors that are applied for the analysis and discrimination of enantiomerical drugs in various media.					
36076310	4	51	from	modifiers	730:738	arg1	modeling					670:677	the molecular mechanics modeling	646:677	the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	646:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	52	theme	suggested	615:623	arg1	approach					625:632	The suggested approach	611:632	The suggested approach	611:632	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	4	53	theme	molecular	650:658	arg1	modeling					670:677	the molecular mechanics modeling	646:677	the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads )	646:810	The suggested approach is based on the molecular mechanics modeling of the adsorption of analyte enantiomers on chiral modifiers and on the comparison of the corresponding adsorption energies (ΔEads ).					
36076310	2	54	theme	modifier	390:397	arg1	structure					366:374	structure	366:374	structure	366:374	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	2	54	theme	modifier	390:397	arg1	factors					411:417	the key factors	403:417	the key factors for the creation of enantioselectivity to a specified analyte	403:479	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	2	54	theme	modifier	390:397	arg1	type					357:360	type	357:360	type	357:360	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	5	55	theme	chiral	976:981	arg1	analytes					983:990	chiral analytes	976:990	chiral analytes	976:990	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	5	56	theme	approach	835:842	arg1	efficiency					817:826	The efficiency	813:826	The efficiency of our approach	813:842	The efficiency of our approach is demonstrated using the example of cyclodextrins and chiral single-wall carbon nanotubes as chiral modifiers, and a wide range of chiral analytes.					
36076310	2	57	theme	chiral	383:388	arg1	modifier					390:397	the chiral modifier	379:397	the chiral modifier	379:397	The type and structure of the chiral modifier are the key factors for the creation of enantioselectivity to a specified analyte.					
36076310	6	58	theme	experimental	1011:1022	arg1	enantioselectivity					1024:1041	the experimental enantioselectivity	1007:1041	the experimental enantioselectivity (ϑexp ) measured using voltammetry	1007:1076	We found that the experimental enantioselectivity (ϑexp ) measured using voltammetry linearly correlates with ΔEads .					
36076310	6	58	theme	experimental	1011:1022	arg1	ϑexp					1044:1047	ϑexp	1044:1047	ϑexp	1044:1047	We found that the experimental enantioselectivity (ϑexp ) measured using voltammetry linearly correlates with ΔEads .					
34949745	0	0	theme	Enzymes	82:88	arg1	Beta-Glucan					94:104	Beta-Glucan	94:104	Beta-Glucan from Hulled Barley	94:123	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	0	0	theme	Enzymes	82:88	arg1	Production					68:77	the Production	64:77	the Production of Enzymes	64:88	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	5	1	theme	fermentation	817:828	arg1	process					830:836	the solid-state fermentation process	801:836	the solid-state fermentation process	801:836	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	3	2	theme	modified	336:343	arg1	g/l					427:429	70 g/l	424:429	70 g/l hulled barley, 0 g/l rice bran	424:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	2	theme	modified	336:343	arg1	composition					362:372	The modified synthetic medium composition	332:372	The modified synthetic medium composition in liquid-state fermentation	332:401	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	3	theme	condition	784:792	arg1	min					764:766	60 min	761:766	60 min of pretreatment condition	761:792	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	3	4	theme	ascorbic	488:495	arg1	acid					497:500	ascorbic acid	488:500	6 g/l ascorbic acid	482:500	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	5	theme	liquid-state	377:388	arg1	fermentation					390:401	liquid-state fermentation	377:401	liquid-state fermentation	377:401	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	5	6	theme	high	919:922	arg1	amounts					924:930	high amounts	919:930	high amounts of enzymes and β-glucan	919:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	6	theme	high	919:922	arg1	β-glucan					947:954	β-glucan	947:954	β-glucan	947:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	6	theme	high	919:922	arg1	enzymes					935:941	enzymes	935:941	enzymes	935:941	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	7	theme	β-glucan	947:954	arg1	amounts					924:930	high amounts	919:930	high amounts of enzymes and β-glucan	919:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	7	theme	β-glucan	947:954	arg1	β-glucan					947:954	β-glucan	947:954	β-glucan	947:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	7	theme	β-glucan	947:954	arg1	enzymes					935:941	enzymes	935:941	enzymes	935:941	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	4	8	theme	U/g	709:711	arg1	U/g					722:724	31310.34 U/g, 2614.95 U/g	700:724	U/g	722:724	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	5	9	theme	hulled	894:899	arg1	barley					901:906	hulled barley	894:906	hulled barley	894:906	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	0	10	theme	Hulled	111:116	arg1	Barley					118:123	Hulled Barley	111:123	Hulled Barley	111:123	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	5	11	theme	overall	863:869	arg1	yields					884:889	the overall fermentation yields	859:889	the overall fermentation yields of hulled barley	859:906	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	2	12	theme	optimal	291:297	arg1	composition					299:309	the optimal composition	287:309	the optimal composition of the basal medium	287:329	The one-factor-at-a-time experiments were carried out to determine the optimal composition of the basal medium.					
34949745	3	13	theme	g/l	448:450	arg1	bran					457:460	hulled barley, 0 g/l rice bran	431:460	bran	457:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	14	from	min	764:766	arg1	w/w					738:740	w/w	738:740	w/w	738:740	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	14	from	min	764:766	arg1	%					735:735	14.6%	731:735	14.6% (w/w)	731:741	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	14	from	min	764:766	arg1	mg/g					694:697	1.26 mg/g	689:697	1.26 mg/g	689:697	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	14	from	min	764:766	arg1	U/g					722:724	31310.34 U/g, 2614.95 U/g	700:724	U/g	722:724	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	0	15	theme	Fermentation	37:48	arg1	Processes					50:58	Fermentation Processes	37:58	Fermentation Processes	37:58	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	3	16	theme	rice	452:455	arg1	bran					457:460	hulled barley, 0 g/l rice bran	431:460	bran	457:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	17	theme	pretreatment	771:782	arg1	condition					784:792	pretreatment condition	771:792	pretreatment condition	771:792	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	3	18	dep	g/l	484:486	arg1	acid					497:500	ascorbic acid	488:500	6 g/l ascorbic acid	482:500	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	19	theme	barley	545:550	arg1	conditions					524:533	Optimal pretreatment conditions	503:533	Optimal pretreatment conditions of hulled barley by solid-state fermentation	503:578	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	2	20	theme	medium	324:329	arg1	composition					299:309	the optimal composition	287:309	the optimal composition of the basal medium	287:329	The one-factor-at-a-time experiments were carried out to determine the optimal composition of the basal medium.					
34949745	4	21	theme	protease	654:661	arg1	production					615:624	maximum production	607:624	maximum production	607:624	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	22	theme	hulled	538:543	arg1	barley					545:550	hulled barley	538:550	hulled barley by solid-state fermentation	538:578	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	2	23	theme	basal	318:322	arg1	medium					324:329	the basal medium	314:329	the basal medium	314:329	The one-factor-at-a-time experiments were carried out to determine the optimal composition of the basal medium.					
34949745	3	24	theme	5	463:463	arg1	g/l					465:467	g/l	465:467	g/l	465:467	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	0	25	theme	Liquid	14:19	arg1	Comparison					0:9	Comparison	0:9	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.	0:124	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	4	26	theme	solid-state	555:565	arg1	fermentation					567:578	solid-state fermentation	555:578	solid-state fermentation	555:578	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	5	27	theme	barley	901:906	arg1	yields					884:889	the overall fermentation yields	859:889	the overall fermentation yields of hulled barley	859:906	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	3	28	from	composition	362:372	arg1	fermentation					390:401	liquid-state fermentation	377:401	liquid-state fermentation	377:401	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	29	theme	g/l	465:467	arg1	soytone					469:475	5 g/l soytone	463:475	5 g/l soytone	463:475	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	30	theme	hulled	431:436	arg1	bran					457:460	hulled barley, 0 g/l rice bran	431:460	bran	457:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	5	31	theme	enzymes	935:941	arg1	amounts					924:930	high amounts	919:930	high amounts of enzymes and β-glucan	919:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	31	theme	enzymes	935:941	arg1	β-glucan					947:954	β-glucan	947:954	β-glucan	947:954	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	5	31	theme	enzymes	935:941	arg1	enzymes					935:941	enzymes	935:941	enzymes	935:941	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	0	32	theme	Solid-State	25:35	arg1	Comparison					0:9	Comparison	0:9	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.	0:124	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	4	33	theme	pretreatment	511:522	arg1	conditions					524:533	Optimal pretreatment conditions	503:533	Optimal pretreatment conditions of hulled barley by solid-state fermentation	503:578	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	3	34	theme	barley	438:443	arg1	bran					457:460	hulled barley, 0 g/l rice bran	431:460	bran	457:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	35	theme	biomass	636:642	arg1	production					615:624	maximum production	607:624	maximum production	607:624	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	36	theme	Optimal	503:509	arg1	conditions					524:533	Optimal pretreatment conditions	503:533	Optimal pretreatment conditions of hulled barley by solid-state fermentation	503:578	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	2	37	theme	one-factor-at-a-time	224:243	arg1	experiments					245:255	The one-factor-at-a-time experiments	220:255	The one-factor-at-a-time experiments	220:255	The one-factor-at-a-time experiments were carried out to determine the optimal composition of the basal medium.					
34949745	3	38	dep	g/l	427:429	arg1	bran					457:460	hulled barley, 0 g/l rice bran	431:460	bran	457:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	1	39	theme	Solid-state	126:136	arg1	fermentation					138:149	Solid-state fermentation	126:149	Solid-state fermentation using hulled barley	126:169	Solid-state fermentation using hulled barley was carried out to produce enzymes and β-glucan.					
34949745	5	40	theme	fermentation	871:882	arg1	yields					884:889	the overall fermentation yields	859:889	the overall fermentation yields of hulled barley	859:906	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	0	41	dep	Liquid	14:19	arg1	Processes					50:58	Fermentation Processes	37:58	Fermentation Processes	37:58	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	5	42	theme	solid-state	805:815	arg1	fermentation					817:828	solid-state fermentation	805:828	the solid-state fermentation process	801:836	Thus, the solid-state fermentation process was found to enhance the overall fermentation yields of hulled barley to produce high amounts of enzymes and β-glucan.					
34949745	3	43	theme	synthetic	345:353	arg1	g/l					427:429	70 g/l	424:429	70 g/l hulled barley, 0 g/l rice bran	424:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	43	theme	synthetic	345:353	arg1	composition					362:372	The modified synthetic medium composition	332:372	The modified synthetic medium composition in liquid-state fermentation	332:401	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	44	theme	fungal	629:634	arg1	biomass					636:642	fungal biomass	629:642	fungal biomass	629:642	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	45	theme	β-glucan	668:675	arg1	production					615:624	maximum production	607:624	maximum production	607:624	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	46	theme	amylase	645:651	arg1	production					615:624	maximum production	607:624	maximum production	607:624	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	4	47	theme	production	615:624	arg1	terms					598:602	terms	598:602	terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition	598:792	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	3	48	theme	medium	355:360	arg1	g/l					427:429	70 g/l	424:429	70 g/l hulled barley, 0 g/l rice bran	424:460	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	3	48	theme	medium	355:360	arg1	composition					362:372	The modified synthetic medium composition	332:372	The modified synthetic medium composition in liquid-state fermentation	332:401	The modified synthetic medium composition in liquid-state fermentation was determined to be 70 g/l hulled barley, 0 g/l rice bran, 5 g/l soytone, and 6 g/l ascorbic acid.					
34949745	4	49	theme	maximum	607:613	arg1	production					615:624	maximum production	607:624	maximum production	607:624	Optimal pretreatment conditions of hulled barley by solid-state fermentation were evaluated in terms of maximum production of fungal biomass, amylase, protease, and β-glucan, which were 1.26 mg/g, 31310.34 U/g, 2614.95 U/g, and 14.6% (w/w), respectively, at 60 min of pretreatment condition.					
34949745	1	50	theme	hulled	157:162	arg1	barley					164:169	hulled barley	157:169	hulled barley	157:169	Solid-state fermentation using hulled barley was carried out to produce enzymes and β-glucan.					
34949745	0	51	from	Barley	118:123	arg1	Beta-Glucan					94:104	Beta-Glucan	94:104	Beta-Glucan from Hulled Barley	94:123	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
34949745	0	51	from	Barley	118:123	arg1	Production					68:77	the Production	64:77	the Production of Enzymes	64:88	Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley.					
36144536	6	0	theme	active	1334:1339	arg1	molecule					1341:1348	the active molecule	1330:1348	the active molecule	1330:1348	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	6	1	theme	molded	1252:1257	arg1	films					1259:1263	compression molded films	1240:1263	compression molded films	1240:1263	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	2	2	theme	tissue	364:369	arg1	formation					341:349	the formation	337:349	the formation of new vital tissue	337:369	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	4	3	theme	Polymeric	565:573	arg1	matrices					575:582	Polymeric matrices	565:582	Polymeric matrices	565:582	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	7	4	theme	blend	1423:1427	arg1	polycaprolactone-gelatin					1429:1452	the blend polycaprolactone-gelatin	1419:1452	the blend polycaprolactone-gelatin	1419:1452	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	6	5	theme	MSG	1086:1088	arg1	MSG					1086:1088	MSG	1086:1088	MSG	1086:1088	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	6	5	theme	MSG	1086:1088	arg1	amount					1076:1081	A higher amount	1067:1081	A higher amount of MSG	1067:1088	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	2	6	theme	vital	358:362	arg1	tissue					364:369	new vital tissue	354:369	new vital tissue	354:369	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	3	7	theme	matrices	488:495	arg1	impregnation					464:475	MSG impregnation	460:475	MSG impregnation of polymer matrices	460:495	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	3	8	theme	carbon	535:540	arg1	process					556:562	a supercritical carbon dioxide-based process	519:562	a supercritical carbon dioxide-based process	519:562	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	1	9	theme	pressure	262:269	arg1	pathologies					242:252	chronic pathologies	234:252	chronic pathologies	234:252	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	1	9	theme	pressure	262:269	arg1	ulcers					271:276	pressure ulcers	262:276	pressure ulcers	262:276	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	3	10	theme	dioxide-based	542:554	arg1	process					556:562	a supercritical carbon dioxide-based process	519:562	a supercritical carbon dioxide-based process	519:562	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	7	11	theme	drug	1400:1403	arg1	rate					1413:1416	the drug release rate	1396:1416	the drug release rate	1396:1416	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	5	12	theme	different	855:863	arg1	techniques					865:874	Two different techniques	851:874	Two different techniques	851:874	Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs.					
36144536	6	13	dep	molded	1252:1257	arg1	compression					1240:1250	compression	1240:1250	compression	1240:1250	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	2	14	from	healing	437:443	arg1	effective					418:426	effective	418:426	effective	418:426	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	6	15	theme	higher	1069:1074	arg1	MSG					1086:1088	MSG	1086:1088	MSG	1086:1088	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	6	15	theme	higher	1069:1074	arg1	amount					1076:1081	A higher amount	1067:1081	A higher amount of MSG	1067:1088	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	4	16	theme	MSG	769:771	arg1	release					773:779	the MSG release	765:779	the MSG release	765:779	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	17	theme	polyethylene	655:666	arg1	polymers					645:652	water-soluble polymers	631:652	water-soluble polymers	631:652	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	17	theme	polyethylene	655:666	arg1	glycol					668:673	polyethylene glycol	655:673	polyethylene glycol	655:673	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	7	18	theme	release	1405:1411	arg1	rate					1413:1416	the drug release rate	1396:1416	the drug release rate	1396:1416	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	4	19	theme	topical	826:832	arg1	administrations					834:848	topical administrations	826:848	topical administrations	826:848	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	6	20	theme	membrane-like	1137:1149	arg1	structures					1151:1160	the membrane-like structures	1133:1160	the membrane-like structures	1133:1160	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	3	21	theme	MSG	460:462	arg1	impregnation					464:475	MSG impregnation	460:475	MSG impregnation of polymer matrices	460:495	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	1	22	theme	increasing	178:187	arg1	aging					189:193	the increasing aging	174:193	the increasing aging of the population	174:211	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	2	23	theme	wound	431:435	arg1	healing					437:443	wound healing	431:443	wound healing	431:443	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	2	24	dep	molecules	285:293	arg1	recruiting					295:304	recruiting	295:304	recruiting cell populations	295:321	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	2	24	dep	molecules	285:293	arg1	promoting					327:335	promoting	327:335	promoting the formation of new vital tissue	327:369	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	1	25	theme	targeted	101:108	arg1	therapies					110:118	targeted therapies	101:118	targeted therapies for wound repair	101:135	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	1	26	theme	therapies	110:118	arg1	development					86:96	The development	82:96	The development of targeted therapies for wound repair	82:135	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	6	27	from	matrix	1123:1128	arg1	structures					1151:1160	the membrane-like structures	1133:1160	the membrane-like structures	1133:1160	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	0	28	theme	Based	29:33	arg1	Composites					35:44	Mesoglycan/PCL Based Composites	14:44	Mesoglycan/PCL Based Composites	14:44	Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation.					
36144536	7	29	theme	water-soluble	1363:1375	arg1	polymer					1377:1383	water-soluble polymer	1363:1383	water-soluble polymer	1363:1383	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	5	30	used	used	886:889	arg2	techniques					865:874	Two different techniques	851:874	Two different techniques	851:874	Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs.					
36144536	3	31	theme	supercritical	521:533	arg1	process					556:562	a supercritical carbon dioxide-based process	519:562	a supercritical carbon dioxide-based process	519:562	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	0	32	theme	Mesoglycan/PCL	14:27	arg1	Composites					35:44	Mesoglycan/PCL Based Composites	14:44	Mesoglycan/PCL Based Composites	14:44	Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation.					
36144536	5	33	theme	compact	960:966	arg1	structures					983:992	compact and continuous structures	960:992	compact and continuous structures	960:992	Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs.					
36144536	1	34	theme	wound	124:128	arg1	repair					130:135	wound repair	124:135	wound repair	124:135	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	1	35	theme	population	202:211	arg1	aging					189:193	the increasing aging	174:193	the increasing aging of the population	174:211	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	7	36	theme	suitable	1492:1499	arg1	release					1472:1478	a prolonged release	1460:1478	a prolonged release potentially suitable for topical administration	1460:1526	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	0	37	theme	Composites	35:44	arg1	Production					0:9	Production	0:9	Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation.	0:80	Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation.					
36144536	6	38	theme	carbon	1276:1281	arg1	dioxide					1283:1289	the carbon dioxide	1272:1289	the carbon dioxide	1272:1289	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	4	39	theme	water-soluble	631:643	arg1	glycol					668:673	polyethylene glycol	655:673	polyethylene glycol	655:673	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	39	theme	water-soluble	631:643	arg1	polymers					645:652	water-soluble polymers	631:652	water-soluble polymers	631:652	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	39	theme	water-soluble	631:643	arg1	gelatin					699:705	gelatin	699:705	gelatin	699:705	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	39	theme	water-soluble	631:643	arg1	pyrrolidone					686:696	polyvinyl pyrrolidone	676:696	polyvinyl pyrrolidone	676:696	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	39	theme	water-soluble	631:643	arg1	starch					726:731	thermoplastic starch	712:731	thermoplastic starch	712:731	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	7	40	theme	topical	1505:1511	arg1	administration					1513:1526	topical administration	1505:1526	topical administration	1505:1526	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	6	41	theme	impregnation	1189:1200	arg1	faster					1213:1218	faster	1213:1218	faster	1213:1218	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	6	41	theme	impregnation	1189:1200	arg1	process					1202:1208	the impregnation process	1185:1208	the impregnation process	1185:1208	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	2	42	theme	new	354:356	arg1	tissue					364:369	new vital tissue	354:369	new vital tissue	354:369	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	4	43	theme	suitable	813:820	arg1	devices					793:799	the devices	789:799	the devices potentially suitable for topical administrations	789:848	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	3	44	theme	polymer	480:486	arg1	matrices					488:495	polymer matrices	480:495	polymer matrices	480:495	In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process.					
36144536	2	45	theme	cell	306:309	arg1	populations					311:321	cell populations	306:321	cell populations	306:321	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	1	46	theme	growing	150:156	arg1	interest					158:165	a growing interest	148:165	a growing interest due to the increasing aging of the population	148:211	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	5	47	theme	continuous	972:981	arg1	structures					983:992	compact and continuous structures	960:992	compact and continuous structures	960:992	Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs.					
36144536	7	48	theme	polymer	1377:1383	arg1	type					1355:1358	The type	1351:1358	The type of water-soluble polymer	1351:1383	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	6	49	theme	polymeric	1113:1121	arg1	matrix					1123:1128	the polymeric matrix	1109:1128	the polymeric matrix in the membrane-like structures	1109:1160	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	6	50	theme	films	1259:1263	arg1	case					1232:1235	the case	1228:1235	the case	1228:1235	A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule.					
36144536	7	51	theme	prolonged	1462:1470	arg1	release					1472:1478	a prolonged release	1460:1478	a prolonged release potentially suitable for topical administration	1460:1526	The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.					
36144536	4	52	theme	thermoplastic	712:724	arg1	polymers					645:652	water-soluble polymers	631:652	water-soluble polymers	631:652	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	52	theme	thermoplastic	712:724	arg1	starch					726:731	thermoplastic starch	712:731	thermoplastic starch	712:731	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	5	53	theme	membrane-like	1044:1056	arg1	designs					1058:1064	membrane-like designs	1044:1064	membrane-like designs	1044:1064	Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs.					
36144536	2	54	theme	sodium	372:377	arg1	MSG					391:393	MSG	391:393	MSG	391:393	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	2	54	theme	sodium	372:377	arg1	mesoglycan					379:388	sodium mesoglycan	372:388	sodium mesoglycan (MSG)	372:394	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	1	55	theme	chronic	234:240	arg1	pathologies					242:252	chronic pathologies	234:252	chronic pathologies	234:252	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	1	55	theme	chronic	234:240	arg1	ulcers					271:276	pressure ulcers	262:276	pressure ulcers	262:276	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	2	56	from	effective	418:426	arg1	healing					437:443	wound healing	431:443	wound healing	431:443	Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing.					
36144536	4	57	theme	polycaprolactone	600:615	arg1	blends					617:622	polycaprolactone blends	600:622	polycaprolactone blends	600:622	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	58	theme	polyvinyl	676:684	arg1	polymers					645:652	water-soluble polymers	631:652	water-soluble polymers	631:652	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	4	58	theme	polyvinyl	676:684	arg1	pyrrolidone					686:696	polyvinyl pyrrolidone	676:696	polyvinyl pyrrolidone	676:696	Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations.					
36144536	1	59	theme	pathologies	242:252	arg1	interest					158:165	a growing interest	148:165	a growing interest due to the increasing aging of the population	148:211	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
36144536	1	59	theme	pathologies	242:252	arg1	incidence					221:229	the incidence	217:229	the incidence of chronic pathologies, mainly pressure ulcers	217:276	The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers.					
37174640	7	0	theme	Thai	1711:1714	arg1	patients					1720:1727	Thai MDD patients	1711:1727	Thai MDD patients	1711:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	1	1	theme	first	216:220	arg1	paper					222:226	the first paper	212:226	the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae	212:492	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	7	2	theme	dysbiosis	1698:1706	arg1	profile					1669:1675	a specific profile	1658:1675	a specific profile of compositional gut dysbiosis in Thai MDD patients	1658:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	7	3	theme	compositional	1680:1692	arg1	dysbiosis					1698:1706	compositional gut dysbiosis	1680:1706	compositional gut dysbiosis in Thai MDD patients	1680:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	1	4	theme	Gram-negative	416:428	arg1	morganii					459:466	Morganella morganii	448:466	Morganella morganii	448:466	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	1	4	theme	Gram-negative	416:428	arg1	bacteria					430:437	Gram-negative bacteria	416:437	Gram-negative bacteria	416:437	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	1	4	theme	Gram-negative	416:428	arg1	Pneumoniae					483:492	Klebsiella Pneumoniae	472:492	Klebsiella Pneumoniae	472:492	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	6	5	theme	Ruminococcus	1453:1464	arg1	exception					1440:1448	the exception	1436:1448	the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models	1436:1631	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	6	theme	microbiome	694:703	arg1	composition					671:681	composition	671:681	composition	671:681	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	6	theme	microbiome	694:703	arg1	profile					659:665	the profile	655:665	the profile	655:665	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	7	7	theme	gut	1694:1696	arg1	dysbiosis					1698:1706	compositional gut dysbiosis	1680:1706	compositional gut dysbiosis in Thai MDD patients	1680:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	3	8	dep	α-	829:830	arg1	Chao1					833:837	Chao1	833:837	Chao1	833:837	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	8	dep	α-	829:830	arg1	indices					851:857	Shannon indices	843:857	Shannon indices	843:857	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	5	9	dep	Desulfovibrio	1290:1302	arg1	piger					1304:1308	Desulfovibrio piger	1290:1308	Desulfovibrio piger	1290:1308	Rhodospirillaceae, Hungatella, Clostridium bolteae, Hungatella hathewayi, and Clostridium propionicum were significantly enriched in MDD, while Gracillibacteraceae family, Lutispora, and Ruminococcus genus, Ruminococcus callidus, Desulfovibrio piger, Coprococcus comes, and Gemmiger were enriched in controls.					
37174640	2	10	theme	gut	544:546	arg1	permeability					548:559	increased gut permeability	534:559	increased gut permeability (leaky gut)	534:571	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	2	10	theme	gut	544:546	arg1	gut					568:570	leaky gut	562:570	leaky gut	562:570	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	3	11	theme	Thai	708:711	arg1	patients					713:720	Thai patients	708:720	Thai patients with MDD	708:729	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	1	12	theme	serum	370:374	arg1	IgM/IgA					376:382	elevated serum IgM/IgA	361:382	elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae	361:492	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	6	13	theme	MDD	1502:1504	arg1	studies					1506:1512	six different MDD studies	1488:1512	six different MDD studies (one study showed increased abundance)	1488:1551	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	14	theme	discriminant	926:937	arg1	LDA					949:951	LDA	949:951	LDA	949:951	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	14	theme	discriminant	926:937	arg1	analysis					939:946	linear discriminant analysis	919:946	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	0	15	theme	Genus	152:156	arg1	Depletion					122:130	Depletion	122:130	Depletion of the Ruminococcus Genus	122:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	3	16	theme	patients	768:775	arg1	samples					750:756	fecal samples	744:756	fecal samples of 32 MDD patients and 37 controls	744:791	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	6	17	theme	medical	1559:1565	arg1	disorders					1567:1575	many medical disorders	1554:1575	many medical disorders that show comorbidities with MDD	1554:1608	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	2	18	from	pathways	625:632	arg1	MDD					637:639	MDD	637:639	MDD	637:639	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	0	19	with	Profile	109:115	arg1	Depletion					122:130	Depletion	122:130	Depletion of the Ruminococcus Genus	122:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	3	20	theme	rDNA	803:806	arg1	sequencing					808:817	16S rDNA sequencing	799:817	16S rDNA sequencing	799:817	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	7	21	from	depletion	1769:1777	arg1	pathobionts					1753:1763	some pathobionts	1748:1763	some pathobionts	1748:1763	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	0	22	theme	Depressive	62:71	arg1	Disorder					73:80	Major Depressive Disorder	56:80	Major Depressive Disorder	56:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	3	23	theme	LEfSe	967:971	arg1	analysis					974:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	6	24	theme	many	1554:1557	arg1	disorders					1567:1575	many medical disorders	1554:1575	many medical disorders that show comorbidities with MDD	1554:1608	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	0	25	from	Exploration	0:10	arg1	Patients					42:49	Thai Patients	37:49	Thai Patients with Major Depressive Disorder	37:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	2	26	theme	neuro-immune	598:609	arg1	pathways					625:632	activated neuro-immune and oxidative pathways	588:632	activated neuro-immune and oxidative pathways in MDD	588:639	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	8	27	theme	universal	1875:1883	arg1	biomarker					1885:1893	a more universal biomarker	1868:1893	a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities	1868:2003	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	8	27	theme	universal	1875:1883	arg1	depletion					1835:1843	depletion	1835:1843	depletion of Ruminococcus	1835:1859	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	3	28	theme	size	961:964	arg1	analysis					974:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	6	29	theme	MDD	1622:1624	arg1	models					1626:1631	animal MDD models	1615:1631	animal MDD models	1615:1631	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	0	30	theme	Specific	90:97	arg1	Biomarker					172:180	a Putative Biomarker	161:180	a Putative Biomarker	161:180	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	0	30	theme	Specific	90:97	arg1	Profile					109:115	a Specific Bacterial Profile	88:115	a Specific Bacterial Profile with Depletion of the Ruminococcus Genus	88:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	8	31	theme	enteral	1935:1941	arg1	load					1947:1950	increased enteral LPS load	1925:1950	increased enteral LPS load	1925:1950	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	6	32	theme	increased	1532:1540	arg1	abundance					1542:1550	increased abundance	1532:1550	increased abundance	1532:1550	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	33	theme	Shannon	843:849	arg1	indices					851:857	Shannon indices	843:857	Shannon indices	843:857	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	7	34	from	patients	1720:1727	arg1	profile					1669:1675	a specific profile	1658:1675	a specific profile of compositional gut dysbiosis in Thai MDD patients	1658:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	2	35	theme	oxidative	615:623	arg1	pathways					625:632	activated neuro-immune and oxidative pathways	588:632	activated neuro-immune and oxidative pathways in MDD	588:639	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	1	36	theme	depressive	253:262	arg1	MDD					274:276	MDD	274:276	MDD	274:276	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	1	36	theme	depressive	253:262	arg1	disorder					264:271	major depressive disorder	247:271	major depressive disorder (MDD)	247:277	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	7	37	theme	microbiota	1798:1807	arg1	depletion					1769:1777	depletion	1769:1777	depletion of some beneficial microbiota	1769:1807	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	7	37	theme	microbiota	1798:1807	arg1	increases					1735:1743	increases	1735:1743	increases in some pathobionts	1735:1763	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	0	38	theme	Microbiome	23:32	arg1	Exploration					0:10	Exploration	0:10	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder	0:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	8	39	theme	increased	1925:1933	arg1	load					1947:1950	increased enteral LPS load	1925:1950	increased enteral LPS load	1925:1950	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	8	40	theme	axis	1986:1989	arg1	abnormalities					1991:2003	gut-brain axis abnormalities	1976:2003	gut-brain axis abnormalities	1976:2003	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	5	41	theme	Coprococcus	1311:1321	arg1	comes					1323:1327	Coprococcus comes	1311:1327	Coprococcus comes	1311:1327	Rhodospirillaceae, Hungatella, Clostridium bolteae, Hungatella hathewayi, and Clostridium propionicum were significantly enriched in MDD, while Gracillibacteraceae family, Lutispora, and Ruminococcus genus, Ruminococcus callidus, Desulfovibrio piger, Coprococcus comes, and Gemmiger were enriched in controls.					
37174640	8	42	theme	LPS	1943:1945	arg1	load					1947:1950	increased enteral LPS load	1925:1950	increased enteral LPS load	1925:1950	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	5	43	dep	Ruminococcus	1247:1258	arg1	genus					1260:1264	genus	1260:1264	genus	1260:1264	Rhodospirillaceae, Hungatella, Clostridium bolteae, Hungatella hathewayi, and Clostridium propionicum were significantly enriched in MDD, while Gracillibacteraceae family, Lutispora, and Ruminococcus genus, Ruminococcus callidus, Desulfovibrio piger, Coprococcus comes, and Gemmiger were enriched in controls.					
37174640	2	44	attach	linked	578:583	arg1	pathways					625:632	activated neuro-immune and oxidative pathways	588:632	activated neuro-immune and oxidative pathways in MDD	588:639	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	2	44	attach	linked	578:583	arg2	aberrations					506:516	The latter aberrations	495:516	The latter aberrations	495:516	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	7	45	theme	MDD	1716:1718	arg1	patients					1720:1727	Thai MDD patients	1711:1727	Thai MDD patients	1711:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	7	46	from	profile	1669:1675	arg1	patients					1720:1727	Thai MDD patients	1711:1727	Thai MDD patients	1711:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	1	47	dep	Maes	183:186	arg1	al					191:192	Maes et al	183:192	Maes et al. (2008)	183:200	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	3	48	theme	Bray-Curtis	877:887	arg1	β-diversity					864:874	β-diversity	864:874	β-diversity (Bray-Curtis dissimilarity)	864:902	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	48	theme	Bray-Curtis	877:887	arg1	dissimilarity					889:901	Bray-Curtis dissimilarity	877:901	Bray-Curtis dissimilarity	877:901	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	0	49	theme	Putative	163:170	arg1	Biomarker					172:180	a Putative Biomarker	161:180	a Putative Biomarker	161:180	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	0	49	theme	Putative	163:170	arg1	Profile					109:115	a Specific Bacterial Profile	88:115	a Specific Bacterial Profile with Depletion of the Ruminococcus Genus	88:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	2	50	theme	leaky	562:566	arg1	permeability					548:559	increased gut permeability	534:559	increased gut permeability (leaky gut)	534:571	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	2	50	theme	leaky	562:566	arg1	gut					568:570	leaky gut	562:570	leaky gut	562:570	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	3	51	theme	linear	919:924	arg1	LDA					949:951	LDA	949:951	LDA	949:951	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	51	theme	linear	919:924	arg1	analysis					939:946	linear discriminant analysis	919:946	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	7	52	from	dysbiosis	1698:1706	arg1	patients					1720:1727	Thai MDD patients	1711:1727	Thai MDD patients	1711:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	1	53	theme	Morganella	448:457	arg1	morganii					459:466	Morganella morganii	448:466	Morganella morganii	448:466	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	0	54	theme	Thai	37:40	arg1	Patients					42:49	Thai Patients	37:49	Thai Patients with Major Depressive Disorder	37:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	7	55	theme	specific	1660:1667	arg1	profile					1669:1675	a specific profile	1658:1675	a specific profile of compositional gut dysbiosis in Thai MDD patients	1658:1727	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	6	56	with	comorbidities	1587:1599	arg1	MDD					1606:1608	MDD	1606:1608	MDD	1606:1608	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	57	from	profile	659:665	arg1	patients					713:720	Thai patients	708:720	Thai patients with MDD	708:729	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	1	58	theme	bacteria	430:437	arg1	LPS					408:410	LPS	408:410	LPS	408:410	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	1	58	theme	bacteria	430:437	arg1	lipopolysaccharides					387:405	lipopolysaccharides	387:405	lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae	387:492	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	3	59	theme	analysis	939:946	arg1	analysis					974:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	60	from	composition	671:681	arg1	patients					713:720	Thai patients	708:720	Thai patients with MDD	708:729	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	61	theme	gut	690:692	arg1	microbiome					694:703	the gut microbiome	686:703	the gut microbiome	686:703	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	2	62	theme	latter	499:504	arg1	aberrations					506:516	The latter aberrations	495:516	The latter aberrations	495:516	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	0	63	theme	Ruminococcus	139:150	arg1	Genus					152:156	the Ruminococcus Genus	135:156	the Ruminococcus Genus	135:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	1	64	theme	elevated	361:368	arg1	IgM/IgA					376:382	elevated serum IgM/IgA	361:382	elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae	361:492	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	2	65	theme	increased	534:542	arg1	permeability					548:559	increased gut permeability	534:559	increased gut permeability (leaky gut)	534:571	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	2	65	theme	increased	534:542	arg1	gut					568:570	leaky gut	562:570	leaky gut	562:570	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	8	66	theme	Ruminococcus	1848:1859	arg1	depletion					1835:1843	depletion	1835:1843	depletion of Ruminococcus	1835:1859	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	8	66	theme	Ruminococcus	1848:1859	arg1	biomarker					1885:1893	a more universal biomarker	1868:1893	a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities	1868:2003	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	6	67	theme	different	1492:1500	arg1	studies					1506:1512	six different MDD studies	1488:1512	six different MDD studies (one study showed increased abundance)	1488:1551	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	68	theme	controls	784:791	arg1	samples					750:756	fecal samples	744:756	fecal samples of 32 MDD patients and 37 controls	744:791	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	5	69	theme	Gracillibacteraceae	1204:1222	arg1	family					1224:1229	Gracillibacteraceae family	1204:1229	Gracillibacteraceae family	1204:1229	Rhodospirillaceae, Hungatella, Clostridium bolteae, Hungatella hathewayi, and Clostridium propionicum were significantly enriched in MDD, while Gracillibacteraceae family, Lutispora, and Ruminococcus genus, Ruminococcus callidus, Desulfovibrio piger, Coprococcus comes, and Gemmiger were enriched in controls.					
37174640	3	70	theme	fecal	744:748	arg1	samples					750:756	fecal samples	744:756	fecal samples of 32 MDD patients and 37 controls	744:791	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	0	71	theme	Major	56:60	arg1	Disorder					73:80	Major Depressive Disorder	56:80	Major Depressive Disorder	56:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	6	72	dep	studies	1506:1512	arg1	showed					1525:1530	showed	1525:1530	showed increased abundance	1525:1550	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	3	73	theme	MDD	764:766	arg1	patients					768:775	32 MDD patients	761:775	32 MDD patients	761:775	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	74	theme	effect	954:959	arg1	analysis					974:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	linear discriminant analysis (LDA) effect size (LEfSe) analysis	919:981	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	75	with	patients	713:720	arg1	MDD					727:729	MDD	727:729	MDD	727:729	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	3	76	theme	16S	799:801	arg1	sequencing					808:817	16S rDNA sequencing	799:817	16S rDNA sequencing	799:817	To delineate the profile and composition of the gut microbiome in Thai patients with MDD, we examined fecal samples of 32 MDD patients and 37 controls using 16S rDNA sequencing, analyzed α- (Chao1 and Shannon indices) and β-diversity (Bray-Curtis dissimilarity), and conducted linear discriminant analysis (LDA) effect size (LEfSe) analysis.					
37174640	2	77	theme	activated	588:596	arg1	pathways					625:632	activated neuro-immune and oxidative pathways	588:632	activated neuro-immune and oxidative pathways in MDD	588:639	The latter aberrations, which point to increased gut permeability (leaky gut), are linked to activated neuro-immune and oxidative pathways in MDD.					
37174640	0	78	theme	Bacterial	99:107	arg1	Biomarker					172:180	a Putative Biomarker	161:180	a Putative Biomarker	161:180	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	0	78	theme	Bacterial	99:107	arg1	Profile					109:115	a Specific Bacterial Profile	88:115	a Specific Bacterial Profile with Depletion of the Ruminococcus Genus	88:156	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	1	79	theme	microbiota-gut-brain	318:337	arg1	axis					339:342	the microbiota-gut-brain axis	314:342	the microbiota-gut-brain axis	314:342	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	8	80	theme	LPS	1953:1955	arg1	translocation					1957:1969	LPS translocation	1953:1969	LPS translocation	1953:1969	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	6	81	theme	animal	1615:1620	arg1	models					1626:1631	animal MDD models	1615:1631	animal MDD models	1615:1631	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	8	82	theme	MDD	1898:1900	arg1	biomarker					1885:1893	a more universal biomarker	1868:1893	a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities	1868:2003	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	8	82	theme	MDD	1898:1900	arg1	depletion					1835:1843	depletion	1835:1843	depletion of Ruminococcus	1835:1859	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	6	83	theme	Contradictory	1370:1382	arg1	results					1384:1390	Contradictory results	1370:1390	Contradictory results	1370:1390	Contradictory results have been reported for all these taxa, with the exception of Ruminococcus, which is depleted in six different MDD studies (one study showed increased abundance), many medical disorders that show comorbidities with MDD, and animal MDD models.					
37174640	0	84	theme	Gut	19:21	arg1	Microbiome					23:32	the Gut Microbiome	15:32	the Gut Microbiome	15:32	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
37174640	1	85	theme	major	247:251	arg1	MDD					274:276	MDD	274:276	MDD	274:276	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	1	85	theme	major	247:251	arg1	disorder					264:271	major depressive disorder	247:271	major depressive disorder (MDD)	247:277	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	7	86	theme	beneficial	1787:1796	arg1	microbiota					1798:1807	some beneficial microbiota	1782:1807	some beneficial microbiota	1782:1807	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	8	87	theme	gut-brain	1976:1984	arg1	abnormalities					1991:2003	gut-brain axis abnormalities	1976:2003	gut-brain axis abnormalities	1976:2003	The results suggest that depletion of Ruminococcus may be a more universal biomarker of MDD that may contribute to increased enteral LPS load, LPS translocation, and gut-brain axis abnormalities.					
37174640	1	88	from	abnormalities	297:309	arg1	axis					339:342	the microbiota-gut-brain axis	314:342	the microbiota-gut-brain axis	314:342	Maes et al. (2008) published the first paper demonstrating that major depressive disorder (MDD) is accompanied by abnormalities in the microbiota-gut-brain axis, as evidenced by elevated serum IgM/IgA to lipopolysaccharides (LPS) of Gram-negative bacteria, such as Morganella morganii and Klebsiella Pneumoniae.					
37174640	7	89	from	increases	1735:1743	arg1	pathobionts					1753:1763	some pathobionts	1748:1763	some pathobionts	1748:1763	Our results may suggest a specific profile of compositional gut dysbiosis in Thai MDD patients, with increases in some pathobionts and depletion of some beneficial microbiota.					
37174640	0	90	with	Patients	42:49	arg1	Disorder					73:80	Major Depressive Disorder	56:80	Major Depressive Disorder	56:80	Exploration of the Gut Microbiome in Thai Patients with Major Depressive Disorder Shows a Specific Bacterial Profile with Depletion of the Ruminococcus Genus as a Putative Biomarker.					
35868746	5	0	theme	mild	887:890	arg1	protocol					908:915	a mild acid hydrolysis protocol	885:915	a mild acid hydrolysis protocol	885:915	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	5	0	theme	mild	887:890	arg1	sufficient					921:930	sufficient	921:930	sufficient	921:930	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	4	1	theme	average	596:602	arg1	degree					619:624	an average polymerization degree	593:624	an average polymerization degree between 29 and 70 AGU	593:646	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	5	2	theme	acid	892:895	arg1	protocol					908:915	a mild acid hydrolysis protocol	885:915	a mild acid hydrolysis protocol	885:915	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	5	2	theme	acid	892:895	arg1	sufficient					921:930	sufficient	921:930	sufficient	921:930	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	6	3	theme	desired	980:986	arg1	degree					1003:1008	the desired polymerization degree	976:1008	the desired polymerization degree	976:1008	Furthermore, the desired polymerization degree could be obtained by tuning the process parameters.					
35868746	0	4	theme	acid	95:98	arg1	hydrolysis					100:109	acid hydrolysis	95:109	acid hydrolysis	95:109	Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.					
35868746	5	5	theme	SMCC	957:960	arg1	yields					947:952	high yields	942:952	high yields of SMCC	942:960	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	4	6	theme	acid	759:762	arg1	hydrolysis					764:773	mild acid hydrolysis	754:773	mild acid hydrolysis	754:773	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	4	7	theme	polymerization	604:617	arg1	degree					619:624	an average polymerization degree	593:624	an average polymerization degree between 29 and 70 AGU	593:646	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	3	8	theme	shorter	354:360	arg1	fibers					372:377	shorter cellulose fibers	354:377	shorter cellulose fibers	354:377	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	9	from	interest	386:393	arg1	search					402:407	the search	398:407	the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites)	398:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	5	10	theme	ball	864:867	arg1	treatment					874:882	an intensive ball mill treatment	851:882	an intensive ball mill treatment	851:882	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	1	11	theme	treatment	166:174	arg1	protocol					176:183	a (pre)treatment protocol	159:183	a (pre)treatment protocol within the catalytic valorization strategies of cellulose	159:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	1	11	theme	treatment	166:174	arg1	Depolymerization					112:127	Depolymerization	112:127	Depolymerization of cellulose	112:140	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	1	12	theme	pre	162:164	arg1	protocol					176:183	a (pre)treatment protocol	159:183	a (pre)treatment protocol within the catalytic valorization strategies of cellulose	159:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	1	12	theme	pre	162:164	arg1	Depolymerization					112:127	Depolymerization	112:127	Depolymerization of cellulose	112:140	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	3	13	theme	cellulose	362:370	arg1	fibers					372:377	shorter cellulose fibers	354:377	shorter cellulose fibers	354:377	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	6	14	theme	polymerization	988:1001	arg1	degree					1003:1008	the desired polymerization degree	976:1008	the desired polymerization degree	976:1008	Furthermore, the desired polymerization degree could be obtained by tuning the process parameters.					
35868746	1	15	used	used	151:154	arg2	Depolymerization					112:127	Depolymerization	112:127	Depolymerization of cellulose	112:140	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	1	15	used	used	151:154	arg2	protocol					176:183	a (pre)treatment protocol	159:183	a (pre)treatment protocol within the catalytic valorization strategies of cellulose	159:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	3	16	theme	renewable	451:459	arg1	materials					461:469	renewable materials	451:469	renewable materials with distinct mechanical properties (bio-composites)	451:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	4	17	with	celluloses	570:579	arg1	degree					619:624	an average polymerization degree	593:624	an average polymerization degree between 29 and 70 AGU	593:646	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	3	18	theme	fiber	432:436	arg1	additives					438:446	accessible dietary fiber additives	413:446	accessible dietary fiber additives	413:446	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	5	19	theme	intensive	854:862	arg1	treatment					874:882	an intensive ball mill treatment	851:882	an intensive ball mill treatment	851:882	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	4	20	theme	mill	731:734	arg1	pretreatment					736:747	a planetary ball mill pretreatment	714:747	a planetary ball mill pretreatment	714:747	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	5	21	theme	polymerization	824:837	arg1	degree					814:819	the levelling-off degree	796:819	the levelling-off degree of polymerization (LODP)	796:844	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	3	22	with	materials	461:469	arg1	bio-composites					508:521	bio-composites	508:521	bio-composites	508:521	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	22	with	materials	461:469	arg1	properties					496:505	distinct mechanical properties	476:505	distinct mechanical properties (bio-composites)	476:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	4	23	theme	mild	754:757	arg1	hydrolysis					764:773	mild acid hydrolysis	754:773	mild acid hydrolysis	754:773	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	3	24	theme	distinct	476:483	arg1	bio-composites					508:521	bio-composites	508:521	bio-composites	508:521	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	24	theme	distinct	476:483	arg1	properties					496:505	distinct mechanical properties	476:505	distinct mechanical properties (bio-composites)	476:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	2	25	theme	anhydroglucose	317:330	arg1	units					332:336	70 anhydroglucose units	314:336	70 anhydroglucose units (AGU)	314:342	Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU).					
35868746	2	25	theme	anhydroglucose	317:330	arg1	AGU					339:341	AGU	339:341	AGU	339:341	Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU).					
35868746	3	26	theme	mechanical	485:494	arg1	bio-composites					508:521	bio-composites	508:521	bio-composites	508:521	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	26	theme	mechanical	485:494	arg1	properties					496:505	distinct mechanical properties	476:505	distinct mechanical properties (bio-composites)	476:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	27	theme	accessible	413:422	arg1	additives					438:446	accessible dietary fiber additives	413:446	accessible dietary fiber additives	413:446	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	1	28	theme	catalytic	196:204	arg1	strategies					219:228	the catalytic valorization strategies	192:228	the catalytic valorization strategies of cellulose	192:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	0	29	theme	polymerization	25:38	arg1	degree					15:20	the degree	11:20	the degree of polymerization of microcrystalline cellulose	11:68	Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.					
35868746	4	30	theme	short-polymer	539:551	arg1	SMCC					582:585	SMCC	582:585	SMCC	582:585	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	4	30	theme	short-polymer	539:551	arg1	celluloses					570:579	short-polymer microcrystalline celluloses	539:579	short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU	539:646	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	3	31	theme	dietary	424:430	arg1	additives					438:446	accessible dietary fiber additives	413:446	accessible dietary fiber additives	413:446	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	1	32	theme	valorization	206:217	arg1	strategies					219:228	the catalytic valorization strategies	192:228	the catalytic valorization strategies of cellulose	192:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	0	33	theme	cellulose	60:68	arg1	polymerization					25:38	polymerization	25:38	polymerization of microcrystalline cellulose	25:68	Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.					
35868746	5	34	theme	mill	869:872	arg1	treatment					874:882	an intensive ball mill treatment	851:882	an intensive ball mill treatment	851:882	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	5	35	theme	levelling-off	800:812	arg1	degree					814:819	the levelling-off degree	796:819	the levelling-off degree of polymerization (LODP)	796:844	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	5	36	theme	hydrolysis	897:906	arg1	protocol					908:915	a mild acid hydrolysis protocol	885:915	a mild acid hydrolysis protocol	885:915	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	5	36	theme	hydrolysis	897:906	arg1	sufficient					921:930	sufficient	921:930	sufficient	921:930	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	0	37	theme	microcrystalline	43:58	arg1	cellulose					60:68	microcrystalline cellulose	43:68	microcrystalline cellulose	43:68	Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.					
35868746	3	38	with	additives	438:446	arg1	bio-composites					508:521	bio-composites	508:521	bio-composites	508:521	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	3	38	with	additives	438:446	arg1	properties					496:505	distinct mechanical properties	476:505	distinct mechanical properties (bio-composites)	476:522	However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites).					
35868746	1	39	theme	cellulose	132:140	arg1	protocol					176:183	a (pre)treatment protocol	159:183	a (pre)treatment protocol within the catalytic valorization strategies of cellulose	159:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	1	39	theme	cellulose	132:140	arg1	Depolymerization					112:127	Depolymerization	112:127	Depolymerization of cellulose	112:140	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	4	40	theme	microcrystalline	553:568	arg1	SMCC					582:585	SMCC	582:585	SMCC	582:585	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	4	40	theme	microcrystalline	553:568	arg1	celluloses					570:579	short-polymer microcrystalline celluloses	539:579	short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU	539:646	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	4	41	theme	ball	726:729	arg1	pretreatment					736:747	a planetary ball mill pretreatment	714:747	a planetary ball mill pretreatment	714:747	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	5	42	theme	high	942:945	arg1	yields					947:952	high yields	942:952	high yields of SMCC	942:960	By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC.					
35868746	2	43	theme	polymerization	285:298	arg1	degrees					300:306	polymerization degrees	285:306	polymerization degrees	285:306	Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU).					
35868746	4	44	theme	planetary	716:724	arg1	pretreatment					736:747	a planetary ball mill pretreatment	714:747	a planetary ball mill pretreatment	714:747	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	0	45	theme	mechanical	73:82	arg1	impact					84:89	mechanical impact	73:89	mechanical impact	73:89	Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.					
35868746	2	46	theme	depolymerization	252:267	arg1	protocols					269:277	Typical depolymerization protocols	244:277	Typical depolymerization protocols	244:277	Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU).					
35868746	6	47	theme	process	1042:1048	arg1	parameters					1050:1059	the process parameters	1038:1059	the process parameters	1038:1059	Furthermore, the desired polymerization degree could be obtained by tuning the process parameters.					
35868746	4	48	theme	material	667:674	arg1	yields					676:681	material yields	667:681	material yields of 95 %	667:689	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
35868746	1	49	theme	cellulose	233:241	arg1	strategies					219:228	the catalytic valorization strategies	192:228	the catalytic valorization strategies of cellulose	192:241	Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose.					
35868746	2	50	theme	Typical	244:250	arg1	protocols					269:277	Typical depolymerization protocols	244:277	Typical depolymerization protocols	244:277	Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU).					
35868746	4	51	theme	%	689:689	arg1	yields					676:681	material yields	667:681	material yields of 95 %	667:689	In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis.					
36308658	12	0	dep	Cr	1600:1601	arg1	VI					1603:1604	VI	1603:1604	VI	1603:1604	After five cycles of adsorption-desorption study, the composite still removed 76% Cr(VI).					
36308658	2	1	theme	structural	348:357	arg1	properties					375:384	The morphological, structural, and electrical properties	329:384	The morphological, structural, and electrical properties of the composite	329:401	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	11	2	theme	electrostatic	1435:1447	arg1	attraction					1449:1458	electrostatic attraction	1435:1458	electrostatic attraction	1435:1458	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	1	3	theme	improved	264:271	arg1	method					281:286	improved Hummers method	264:286	improved Hummers method	264:286	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	8	4	theme	flow	1104:1107	arg1	rate					1109:1112	a lower flow rate	1096:1112	a lower flow rate	1096:1112	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	8	4	theme	flow	1104:1107	arg1	suitable					1143:1150	suitable	1143:1150	suitable	1143:1150	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	4	5	theme	adsorption	609:618	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	5	theme	adsorption	609:618	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	13	6	theme	GO	1671:1672	arg1	composite					1682:1690	GO@CS-PANI composite	1671:1690	GO@CS-PANI composite	1671:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	11	7	theme	ion	1478:1480	arg1	exchange					1482:1489	ion exchange	1478:1489	ion exchange	1478:1489	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	0	8	link	cross-linked	53:64	arg1	composite					78:86	porous chitosan cross-linked polyaniline composite	37:86	porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI)	37:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	13	9	theme	study	1638:1642	arg1	findings					1614:1621	These findings	1608:1621	These findings of the present study	1608:1642	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	13	9	theme	study	1638:1642	arg1	nature					1661:1666	the reusable nature	1648:1666	the reusable nature of GO@CS-PANI composite	1648:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	1	10	theme	graphene	183:190	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	8	11	theme	higher	1120:1125	arg1	height					1131:1136	a higher bed height	1118:1136	a higher bed height	1118:1136	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	8	11	theme	higher	1120:1125	arg1	suitable					1143:1150	suitable	1143:1150	suitable	1143:1150	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	3	12	theme	excellent	521:529	arg1	performance					546:556	excellent Cr(VI) removal performance	521:556	excellent Cr(VI) removal performance	521:556	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	1	13	theme	porous	207:212	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	7	14	theme	Thermodynamic	957:969	arg1	data					971:974	Thermodynamic data	957:974	Thermodynamic data	957:974	Thermodynamic data demonstrated that the process was spontaneous, endothermic, and feasible.					
36308658	1	15	theme	cross-linked	223:234	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	6	16	theme	kinetic	895:901	arg1	model					903:907	the best-fitted kinetic model	879:907	the best-fitted kinetic model	879:907	Pseudo-second-order was the best-fitted kinetic model, and the rate was controlled by film diffusion.					
36308658	6	16	theme	kinetic	895:901	arg1	Pseudo-second-order					855:873	Pseudo-second-order	855:873	Pseudo-second-order	855:873	Pseudo-second-order was the best-fitted kinetic model, and the rate was controlled by film diffusion.					
36308658	9	17	theme	Thomas	1192:1197	arg1	model					1225:1229	the best-fitted model	1209:1229	the best-fitted model for data obtained from the dynamic study	1209:1270	The Thomas model was the best-fitted model for data obtained from the dynamic study.					
36308658	9	17	theme	Thomas	1192:1197	arg1	model					1199:1203	The Thomas model	1188:1203	The Thomas model	1188:1203	The Thomas model was the best-fitted model for data obtained from the dynamic study.					
36308658	2	18	theme	zeta	467:470	arg1	potential					472:480	zeta potential	467:480	zeta potential	467:480	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	5	19	theme	maximum	824:830	arg1	uptake					832:837	maximum uptake	824:837	maximum uptake of 539.83 mg/g	824:852	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	12	20	theme	76	1596:1597	arg1	%					1598:1598	%	1598:1598	%	1598:1598	After five cycles of adsorption-desorption study, the composite still removed 76% Cr(VI).					
36308658	0	21	theme	static	92:97	arg1	removal					111:117	static and dynamic removal	92:117	static and dynamic removal of Cr(VI)	92:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	9	22	theme	best-fitted	1213:1223	arg1	model					1225:1229	the best-fitted model	1209:1229	the best-fitted model for data obtained from the dynamic study	1209:1270	The Thomas model was the best-fitted model for data obtained from the dynamic study.					
36308658	9	22	theme	best-fitted	1213:1223	arg1	model					1199:1203	The Thomas model	1188:1203	The Thomas model	1188:1203	The Thomas model was the best-fitted model for data obtained from the dynamic study.					
36308658	4	23	theme	45 min	696:701	arg1	pH					648:649	pH	648:649	pH of 2.0	648:656	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	23	theme	45 min	696:701	arg1	temperature					708:718	temperature	708:718	temperature of 35 °C	708:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	23	theme	45 min	696:701	arg1	time					688:691	time	688:691	time of 45 min	688:701	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	23	theme	45 min	696:701	arg1	dosage					669:674	adsorbent dosage	659:674	adsorbent dosage of 0.4 g/L	659:685	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	11	24	theme	adsorption	1405:1414	arg1	mechanism					1416:1424	The adsorption mechanism	1401:1424	The adsorption mechanism	1401:1424	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	0	25	theme	dynamic	103:109	arg1	removal					111:117	static and dynamic removal	92:117	static and dynamic removal of Cr(VI)	92:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	2	26	theme	composite	393:401	arg1	properties					375:384	The morphological, structural, and electrical properties	329:384	The morphological, structural, and electrical properties of the composite	329:401	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	4	27	from	time	688:691	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	27	from	time	688:691	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	28	theme	0.4 g/L	679:685	arg1	pH					648:649	pH	648:649	pH of 2.0	648:656	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	28	theme	0.4 g/L	679:685	arg1	temperature					708:718	temperature	708:718	temperature of 35 °C	708:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	28	theme	0.4 g/L	679:685	arg1	time					688:691	time	688:691	time of 45 min	688:701	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	28	theme	0.4 g/L	679:685	arg1	dosage					669:674	adsorbent dosage	659:674	adsorbent dosage of 0.4 g/L	659:685	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	5	29	theme	Langmuir	734:741	arg1	model					778:782	the best-fitted model	762:782	the best-fitted model	762:782	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	5	29	theme	Langmuir	734:741	arg1	model					752:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	1	30	theme	Hummers	273:279	arg1	method					281:286	improved Hummers method	264:286	improved Hummers method	264:286	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	0	31	theme	graphene	13:20	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of graphene	0:20	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	12	32	theme	study	1561:1565	arg1	cycles					1529:1534	five cycles	1524:1534	five cycles of adsorption-desorption study	1524:1565	After five cycles of adsorption-desorption study, the composite still removed 76% Cr(VI).					
36308658	2	33	theme	FTIR	449:452	arg1	spectra					454:460	FTIR spectra	449:460	FTIR spectra	449:460	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	10	34	theme	such	1388:1391	arg1	effect					1393:1398	no such effect	1385:1398	no such effect	1385:1398	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	8	35	theme	maximum	1156:1162	arg1	performance					1175:1185	maximum adsorption performance	1156:1185	maximum adsorption performance	1156:1185	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	0	36	theme	porous	37:42	arg1	composite					78:86	porous chitosan cross-linked polyaniline composite	37:86	porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI)	37:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	11	37	theme	ion	1502:1504	arg1	complexion					1506:1515	metal ion complexion	1496:1515	metal ion complexion	1496:1515	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	0	38	theme	cross-linked	53:64	arg1	composite					78:86	porous chitosan cross-linked polyaniline composite	37:86	porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI)	37:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	10	39	theme	Cr	1348:1349	arg1	removal					1355:1361	Cr(VI) removal	1348:1361	Cr(VI) removal	1348:1361	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	8	40	theme	dynamic	1059:1065	arg1	study					1067:1071	the dynamic study	1055:1071	the dynamic study	1055:1071	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	1	41	theme	novel	132:136	arg1	composite					146:154	A novel ternary composite	130:154	A novel ternary composite	130:154	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	13	42	theme	@	1673:1673	arg1	composite					1682:1690	GO@CS-PANI composite	1671:1690	GO@CS-PANI composite	1671:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	10	43	theme	interfering	1290:1300	arg1	ions					1302:1305	interfering ions	1290:1305	interfering ions	1290:1305	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	2	44	theme	electrical	364:373	arg1	properties					375:384	The morphological, structural, and electrical properties	329:384	The morphological, structural, and electrical properties of the composite	329:401	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	10	45	dep	removal	1355:1361	arg1	VI					1351:1352	VI	1351:1352	VI	1351:1352	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	13	46	theme	composite	1682:1690	arg1	findings					1614:1621	These findings	1608:1621	These findings of the present study	1608:1642	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	13	46	theme	composite	1682:1690	arg1	nature					1661:1666	the reusable nature	1648:1666	the reusable nature of GO@CS-PANI composite	1648:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	4	47	from	pH	648:649	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	47	from	pH	648:649	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	1	48	theme	@	251:251	arg1	CS-PANI					252:258	@CS-PANI	251:258	@CS-PANI	251:258	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	13	49	theme	reusable	1652:1659	arg1	nature					1661:1666	the reusable nature	1648:1666	the reusable nature of GO@CS-PANI composite	1648:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	11	50	theme	π-π	1461:1463	arg1	interaction					1465:1475	π-π interaction	1461:1475	π-π interaction	1461:1475	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	8	51	theme	lower	1098:1102	arg1	rate					1109:1112	a lower flow rate	1096:1112	a lower flow rate	1096:1112	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	8	51	theme	lower	1098:1102	arg1	suitable					1143:1150	suitable	1143:1150	suitable	1143:1150	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	4	52	theme	optimal	601:607	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	52	theme	optimal	601:607	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	13	53	theme	present	1630:1636	arg1	study					1638:1642	the present study	1626:1642	the present study	1626:1642	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	3	54	theme	Cr	531:532	arg1	performance					546:556	excellent Cr(VI) removal performance	521:556	excellent Cr(VI) removal performance	521:556	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	5	55	theme	homogeneous	796:806	arg1	adsorption					808:817	homogeneous adsorption	796:817	homogeneous adsorption	796:817	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	8	56	theme	adsorption	1164:1173	arg1	performance					1175:1185	maximum adsorption performance	1156:1185	maximum adsorption performance	1156:1185	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	10	57	theme	little	1331:1336	arg1	effect					1338:1343	little effect	1331:1343	little effect	1331:1343	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	1	58	theme	oxide-modified	192:205	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	3	59	theme	removal	538:544	arg1	performance					546:556	excellent Cr(VI) removal performance	521:556	excellent Cr(VI) removal performance	521:556	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	3	60	dep	performance	546:556	arg1	VI					534:535	VI	534:535	VI	534:535	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	5	61	theme	best-fitted	766:776	arg1	model					778:782	the best-fitted model	762:782	the best-fitted model	762:782	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	5	61	theme	best-fitted	766:776	arg1	model					752:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	8	62	theme	bed	1127:1129	arg1	height					1131:1136	a higher bed height	1118:1136	a higher bed height	1118:1136	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	8	62	theme	bed	1127:1129	arg1	suitable					1143:1150	suitable	1143:1150	suitable	1143:1150	From the dynamic study, it was witnessed that a lower flow rate and a higher bed height were suitable for maximum adsorption performance.					
36308658	1	63	dep	polyaniline	236:246	arg1	GO					249:250	GO	249:250	GO@CS-PANI	249:258	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	5	64	theme	539.83 mg/g	842:852	arg1	uptake					832:837	maximum uptake	824:837	maximum uptake of 539.83 mg/g	824:852	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	6	65	theme	best-fitted	883:893	arg1	model					903:907	the best-fitted kinetic model	879:907	the best-fitted kinetic model	879:907	Pseudo-second-order was the best-fitted kinetic model, and the rate was controlled by film diffusion.					
36308658	6	65	theme	best-fitted	883:893	arg1	Pseudo-second-order					855:873	Pseudo-second-order	855:873	Pseudo-second-order	855:873	Pseudo-second-order was the best-fitted kinetic model, and the rate was controlled by film diffusion.					
36308658	4	66	theme	2.0	654:656	arg1	pH					648:649	pH	648:649	pH of 2.0	648:656	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	66	theme	2.0	654:656	arg1	temperature					708:718	temperature	708:718	temperature of 35 °C	708:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	66	theme	2.0	654:656	arg1	time					688:691	time	688:691	time of 45 min	688:701	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	66	theme	2.0	654:656	arg1	dosage					669:674	adsorbent dosage	659:674	adsorbent dosage of 0.4 g/L	659:685	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	3	67	theme	static	566:571	arg1	adsorption					585:594	static and dynamic adsorption	566:594	static and dynamic adsorption	566:594	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	4	68	theme	adsorbent	659:667	arg1	dosage					669:674	adsorbent dosage	659:674	adsorbent dosage of 0.4 g/L	659:685	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	69	from	temperature	708:718	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	69	from	temperature	708:718	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	1	70	theme	ternary	138:144	arg1	composite					146:154	A novel ternary composite	130:154	A novel ternary composite	130:154	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	6	71	theme	film	941:944	arg1	diffusion					946:954	film diffusion	941:954	film diffusion	941:954	Pseudo-second-order was the best-fitted kinetic model, and the rate was controlled by film diffusion.					
36308658	1	72	link	cross-linked	223:234	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	0	73	dep	Cr	122:123	arg1	VI					125:126	VI	125:126	VI	125:126	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	12	74	theme	%	1598:1598	arg1	Cr					1600:1601	76% Cr	1596:1601	76% Cr(VI)	1596:1605	After five cycles of adsorption-desorption study, the composite still removed 76% Cr(VI).					
36308658	0	75	theme	Cr	122:123	arg1	removal					111:117	static and dynamic removal	92:117	static and dynamic removal of Cr(VI)	92:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	13	76	theme	wastewater	1743:1752	arg1	treatment					1754:1762	wastewater treatment	1743:1762	wastewater treatment	1743:1762	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	5	77	theme	isotherm	743:750	arg1	model					778:782	the best-fitted model	762:782	the best-fitted model	762:782	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	5	77	theme	isotherm	743:750	arg1	model					752:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model	730:756	The Langmuir isotherm model was the best-fitted model, indicating homogeneous adsorption with maximum uptake of 539.83 mg/g.					
36308658	9	78	theme	dynamic	1258:1264	arg1	study					1266:1270	the dynamic study	1254:1270	the dynamic study	1254:1270	The Thomas model was the best-fitted model for data obtained from the dynamic study.					
36308658	0	79	theme	chitosan	44:51	arg1	composite					78:86	porous chitosan cross-linked polyaniline composite	37:86	porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI)	37:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	1	80	theme	chitosan	214:221	arg1	polyaniline					236:246	graphene oxide-modified porous chitosan cross-linked polyaniline	183:246	graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI)	183:259	A novel ternary composite was synthesized comprising graphene oxide-modified porous chitosan cross-linked polyaniline (GO@CS-PANI) by improved Hummers method, followed by cross-linking and grafting.					
36308658	12	81	theme	adsorption-desorption	1539:1559	arg1	study					1561:1565	adsorption-desorption study	1539:1565	adsorption-desorption study	1539:1565	After five cycles of adsorption-desorption study, the composite still removed 76% Cr(VI).					
36308658	10	82	from	ions	1302:1305	arg1	Competition					1273:1283	Competition	1273:1283	Competition from interfering ions	1273:1305	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	3	83	theme	dynamic	577:583	arg1	adsorption					585:594	static and dynamic adsorption	566:594	static and dynamic adsorption	566:594	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	11	84	theme	metal	1496:1500	arg1	complexion					1506:1515	metal ion complexion	1496:1515	metal ion complexion	1496:1515	The adsorption mechanism involved electrostatic attraction, π-π interaction, ion exchange, and metal ion complexion.					
36308658	0	85	theme	polyaniline	66:76	arg1	composite					78:86	porous chitosan cross-linked polyaniline composite	37:86	porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI)	37:127	Synthesis of graphene oxide-modified porous chitosan cross-linked polyaniline composite for static and dynamic removal of Cr(VI).					
36308658	2	86	theme	morphological	333:345	arg1	properties					375:384	The morphological, structural, and electrical properties	329:384	The morphological, structural, and electrical properties of the composite	329:401	The morphological, structural, and electrical properties of the composite were characterized by FESEM, BET, XRD, RAMAN, FTIR spectra, and zeta potential.					
36308658	4	87	from	dosage	669:674	arg1	solution					636:643	solution	636:643	solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C	636:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	87	from	dosage	669:674	arg1	parameters					620:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters	597:629	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	3	88	dep	adsorption	585:594	arg1	both					558:561	both	558:561	both	558:561	It was found that the composite shows excellent Cr(VI) removal performance both in static and dynamic adsorption.					
36308658	10	89	contain	have	1380:1383	arg1	cations					1372:1378	cations	1372:1378	cations	1372:1378	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	10	89	contain	have	1380:1383	arg2	effect					1393:1398	no such effect	1385:1398	no such effect	1385:1398	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	13	90	theme	CS-PANI	1674:1680	arg1	composite					1682:1690	GO@CS-PANI composite	1671:1690	GO@CS-PANI composite	1671:1690	These findings of the present study and the reusable nature of GO@CS-PANI composite signify the innovative and excellent adsorbent for wastewater treatment.					
36308658	4	91	theme	35 °C	723:727	arg1	pH					648:649	pH	648:649	pH of 2.0	648:656	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	91	theme	35 °C	723:727	arg1	temperature					708:718	temperature	708:718	temperature of 35 °C	708:727	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	91	theme	35 °C	723:727	arg1	time					688:691	time	688:691	time of 45 min	688:701	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	4	91	theme	35 °C	723:727	arg1	dosage					669:674	adsorbent dosage	659:674	adsorbent dosage of 0.4 g/L	659:685	The optimal adsorption parameters were solution at pH of 2.0, adsorbent dosage of 0.4 g/L, time of 45 min, and temperature of 35 °C.					
36308658	10	92	contain	have	1326:1329	arg1	anions					1319:1324	anions	1319:1324	anions	1319:1324	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
36308658	10	92	contain	have	1326:1329	arg2	effect					1338:1343	little effect	1331:1343	little effect	1331:1343	Competition from interfering ions showed that anions have little effect on Cr(VI) removal, whereas cations have no such effect.					
37001343	4	0	theme	dosage	701:706	arg1	Effect					687:692	Effect	687:692	Effect of CuS dosage, pH value, light source and intensity	687:744	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	3	1	theme	high	516:519	arg1	ability					539:545	high Cr(VI) adsorption ability	516:545	high Cr(VI) adsorption ability	516:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	0	2	theme	Cr	98:99	arg1	removal					105:111	enhanced Cr(VI) removal	89:111	enhanced Cr(VI) removal	89:111	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	8	3	theme	surface	1388:1394	arg1	charge					1396:1401	the surface charge and light absorbance ability	1384:1430	charge	1396:1401	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	3	4	theme	Cr	521:522	arg1	ability					539:545	high Cr(VI) adsorption ability	516:545	high Cr(VI) adsorption ability	516:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	8	5	theme	Cr	1458:1459	arg1	removal					1465:1471	the Cr(VI) removal	1454:1471	the Cr(VI) removal	1454:1471	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	1	6	theme	environmental	252:264	arg1	Photocatalysis					141:154	Photocatalysis	141:154	Photocatalysis	141:154	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	1	6	theme	environmental	252:264	arg1	method					275:280	an efficient and environmental friendly method	235:280	an efficient and environmental friendly method	235:280	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	5	7	dep	Cr	875:876	arg1	VI					878:879	VI	878:879	VI	878:879	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	4	8	theme	optimum	769:775	arg1	Cr					777:778	the optimum Cr(VI) removal conditions	765:801	the optimum Cr(VI) removal conditions	765:801	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	5	9	theme	citric	973:978	arg1	acid					980:983	citric acid	973:983	citric acid	973:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	7	10	theme	Cr	1336:1337	arg1	reduction					1323:1331	the reduction	1319:1331	the reduction of Cr(VI)	1319:1341	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	2	11	theme	conventional	292:303	arg1	photocatalysts					305:318	conventional photocatalysts	292:318	conventional photocatalysts	292:318	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	5	12	theme	light	950:954	arg1	irradiation					956:966	UV light irradiation	947:966	UV light irradiation with citric acid	947:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	1	13	theme	friendly	266:273	arg1	Photocatalysis					141:154	Photocatalysis	141:154	Photocatalysis	141:154	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	1	13	theme	friendly	266:273	arg1	method					275:280	an efficient and environmental friendly method	235:280	an efficient and environmental friendly method	235:280	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	3	14	theme	CuS	568:570	arg1	nanocrystals					572:583	prepared CuS nanocrystals	559:583	prepared CuS nanocrystals into triethylenetetramine modified sodium alginate	559:634	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	6	15	theme	adsorption	1176:1185	arg1	process					1187:1193	the adsorption process	1172:1193	the adsorption process	1172:1193	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	7	16	theme	amino	1236:1240	arg1	groups					1255:1260	amino and hydroxyl groups	1236:1260	groups	1255:1260	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	0	17	dep	removal	105:111	arg1	VI					101:102	VI	101:102	VI	101:102	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	3	18	dep	Cr	679:680	arg1	VI					682:683	VI	682:683	VI	682:683	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	3	19	theme	composite	492:500	arg1	material					502:509	a novel composite material	484:509	a novel composite material with high Cr(VI) adsorption ability	484:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	4	20	theme	CuS	697:699	arg1	dosage					701:706	CuS dosage	697:706	CuS dosage	697:706	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	6	21	with	kinetics	1045:1052	arg1	fitting					1079:1085	corresponding model fitting	1059:1085	corresponding model fitting	1059:1085	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	5	22	theme	synthesized	808:818	arg1	composite					820:828	The synthesized composite	804:828	The synthesized composite	804:828	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	1	23	theme	hexavalent	196:205	arg1	chromium					207:214	hexavalent chromium	196:214	hexavalent chromium	196:214	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	5	24	theme	adsorption	845:854	arg1	performance					856:866	good adsorption performance	840:866	good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid	840:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	6	25	theme	Adsorption	1004:1013	arg1	isotherm					1015:1022	Adsorption isotherm	1004:1022	Adsorption isotherm	1004:1022	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	3	26	theme	adsorption	528:537	arg1	ability					539:545	high Cr(VI) adsorption ability	516:545	high Cr(VI) adsorption ability	516:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	8	27	theme	CuS	1355:1357	arg1	nanocrystals					1359:1370	CuS nanocrystals	1355:1370	CuS nanocrystals	1355:1370	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	2	28	theme	unsatisfactory	393:406	arg1	performance					408:418	unsatisfactory performance	393:418	unsatisfactory performance in high concentrated wastewaters	393:451	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	7	29	dep	Cr	1336:1337	arg1	VI					1339:1340	VI	1339:1340	VI	1339:1340	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	7	30	theme	Characterization	1196:1211	arg1	results					1213:1219	Characterization results	1196:1219	Characterization results	1196:1219	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	3	31	with	material	502:509	arg1	ability					539:545	high Cr(VI) adsorption ability	516:545	high Cr(VI) adsorption ability	516:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	5	32	with	irradiation	956:966	arg1	acid					980:983	citric acid	973:983	citric acid	973:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	2	33	theme	poor	338:341	arg1	properties					354:363	poor adsorption properties	338:363	poor adsorption properties	338:363	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	4	34	dep	Cr	777:778	arg1	VI					780:781	VI	780:781	VI	780:781	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	4	34	dep	Cr	777:778	arg1	conditions					792:801	removal conditions	784:801	the optimum Cr(VI) removal conditions	765:801	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	4	35	theme	value	712:716	arg1	Effect					687:692	Effect	687:692	Effect of CuS dosage, pH value, light source and intensity	687:744	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	7	36	from	electrons	1274:1282	arg1	reaction					1306:1313	the photocatalysis reaction	1287:1313	the photocatalysis reaction	1287:1313	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	4	37	theme	light	719:723	arg1	source					725:730	light source	719:730	light source	719:730	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	3	38	theme	Cr	679:680	arg1	removal					668:674	the enhanced photocatalytic removal	640:674	the enhanced photocatalytic removal of Cr(VI)	640:684	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	5	39	theme	overall	890:896	arg1	rate					906:909	the overall removal rate	886:909	the overall removal rate reached 98.99 % within 50 min	886:939	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	2	40	dep	Cr	372:373	arg1	VI					375:376	VI	375:376	VI	375:376	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	4	41	theme	removal	784:790	arg1	conditions					792:801	removal conditions	784:801	the optimum Cr(VI) removal conditions	765:801	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	0	42	theme	triethylenetetramine	13:32	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of triethylenetetramine	0:32	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	6	43	with	thermodynamics	1025:1038	arg1	fitting					1079:1085	corresponding model fitting	1059:1085	corresponding model fitting	1059:1085	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	3	44	theme	prepared	559:566	arg1	nanocrystals					572:583	prepared CuS nanocrystals	559:583	prepared CuS nanocrystals into triethylenetetramine modified sodium alginate	559:634	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	2	45	theme	concentrated	428:439	arg1	wastewaters					441:451	high concentrated wastewaters	423:451	high concentrated wastewaters	423:451	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	0	46	theme	alginate/CuS	50:61	arg1	composite					75:83	sodium alginate/CuS nanocrystal composite	43:83	sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal	43:111	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	8	47	theme	redox	1533:1537	arg1	reaction					1539:1546	photo-induced redox reaction	1519:1546	photo-induced redox reaction	1519:1546	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	1	48	theme	chromium	207:214	arg1	removal					185:191	the removal	181:191	the removal of hexavalent chromium from wastewater	181:230	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	3	49	theme	modified	611:618	arg1	alginate					627:634	triethylenetetramine modified sodium alginate	590:634	triethylenetetramine modified sodium alginate	590:634	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	2	50	theme	high	423:426	arg1	wastewaters					441:451	high concentrated wastewaters	423:451	high concentrated wastewaters	423:451	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	0	51	theme	sodium	43:48	arg1	composite					75:83	sodium alginate/CuS nanocrystal composite	43:83	sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal	43:111	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	8	52	theme	photo-induced	1519:1531	arg1	reaction					1539:1546	photo-induced redox reaction	1519:1546	photo-induced redox reaction	1519:1546	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	5	53	theme	removal	898:904	arg1	rate					906:909	the overall removal rate	886:909	the overall removal rate reached 98.99 % within 50 min	886:939	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	3	54	theme	photocatalytic	653:666	arg1	removal					668:674	the enhanced photocatalytic removal	640:674	the enhanced photocatalytic removal of Cr(VI)	640:684	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	3	55	theme	sodium	620:625	arg1	alginate					627:634	triethylenetetramine modified sodium alginate	590:634	triethylenetetramine modified sodium alginate	590:634	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	8	56	theme	light	1407:1411	arg1	ability					1424:1430	the surface charge and light absorbance ability	1384:1430	ability	1424:1430	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	7	57	theme	photocatalysis	1291:1304	arg1	reaction					1306:1313	the photocatalysis reaction	1287:1313	the photocatalysis reaction	1287:1313	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	8	58	theme	absorbance	1413:1422	arg1	ability					1424:1430	the surface charge and light absorbance ability	1384:1430	ability	1424:1430	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	4	59	theme	pH	709:710	arg1	value					712:716	pH value	709:716	pH value	709:716	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	0	60	theme	nanocrystal	63:73	arg1	composite					75:83	sodium alginate/CuS nanocrystal composite	43:83	sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal	43:111	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	6	61	theme	chemical	1142:1149	arg1	adsorption					1151:1160	the monolayer and chemical adsorption	1124:1160	the monolayer and chemical adsorption	1124:1160	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	8	62	theme	electrostatic	1489:1501	arg1	interaction					1503:1513	electrostatic interaction	1489:1513	electrostatic interaction	1489:1513	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	5	63	theme	hole	988:991	arg1	scavenger					993:1001	hole scavenger	988:1001	hole scavenger	988:1001	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	2	64	from	performance	408:418	arg1	wastewaters					441:451	high concentrated wastewaters	423:451	high concentrated wastewaters	423:451	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	7	65	theme	hydroxyl	1246:1253	arg1	groups					1255:1260	amino and hydroxyl groups	1236:1260	groups	1255:1260	Characterization results indicated that amino and hydroxyl groups contributed electrons in the photocatalysis reaction for the reduction of Cr(VI) to Cr(III).					
37001343	1	66	from	wastewater	221:230	arg1	removal					185:191	the removal	181:191	the removal of hexavalent chromium from wastewater	181:230	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	4	67	theme	source	725:730	arg1	Effect					687:692	Effect	687:692	Effect of CuS dosage, pH value, light source and intensity	687:744	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	0	68	dep	modified	34:41	arg1	mechanism					130:138	mechanism	130:138	mechanism	130:138	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	0	68	dep	modified	34:41	arg1	Performance					114:124	Performance	114:124	Performance	114:124	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	3	69	theme	novel	486:490	arg1	material					502:509	a novel composite material	484:509	a novel composite material with high Cr(VI) adsorption ability	484:545	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	4	70	theme	intensity	736:744	arg1	Effect					687:692	Effect	687:692	Effect of CuS dosage, pH value, light source and intensity	687:744	Effect of CuS dosage, pH value, light source and intensity were discussed for the optimum Cr(VI) removal conditions.					
37001343	6	71	theme	monolayer	1128:1136	arg1	adsorption					1151:1160	the monolayer and chemical adsorption	1124:1160	the monolayer and chemical adsorption	1124:1160	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	6	72	with	isotherm	1015:1022	arg1	fitting					1079:1085	corresponding model fitting	1059:1085	corresponding model fitting	1059:1085	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	3	73	theme	enhanced	644:651	arg1	removal					668:674	the enhanced photocatalytic removal	640:674	the enhanced photocatalytic removal of Cr(VI)	640:684	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	2	74	theme	adsorption	343:352	arg1	properties					354:363	poor adsorption properties	338:363	poor adsorption properties	338:363	However, conventional photocatalysts generally exhibit poor adsorption properties toward Cr(VI), resulting in unsatisfactory performance in high concentrated wastewaters.					
37001343	3	75	dep	ability	539:545	arg1	VI					524:525	VI	524:525	VI	524:525	In this study, we synthesized a novel composite material with high Cr(VI) adsorption ability by blending prepared CuS nanocrystals into triethylenetetramine modified sodium alginate for the enhanced photocatalytic removal of Cr(VI).					
37001343	0	76	theme	enhanced	89:96	arg1	removal					105:111	enhanced Cr(VI) removal	89:111	enhanced Cr(VI) removal	89:111	Synthesis of triethylenetetramine modified sodium alginate/CuS nanocrystal composite for enhanced Cr(VI) removal: Performance and mechanism.					
37001343	8	77	theme	composite	1439:1447	arg1	ability					1424:1430	the surface charge and light absorbance ability	1384:1430	ability	1424:1430	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	8	77	theme	composite	1439:1447	arg1	charge					1396:1401	the surface charge and light absorbance ability	1384:1430	charge	1396:1401	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	6	78	theme	model	1073:1077	arg1	fitting					1079:1085	corresponding model fitting	1059:1085	corresponding model fitting	1059:1085	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	5	79	theme	good	840:843	arg1	performance					856:866	good adsorption performance	840:866	good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid	840:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	5	80	theme	UV	947:948	arg1	irradiation					956:966	UV light irradiation	947:966	UV light irradiation with citric acid	947:983	The synthesized composite has shown good adsorption performance toward Cr(VI) and the overall removal rate reached 98.99 % within 50 min under UV light irradiation with citric acid as hole scavenger.					
37001343	1	81	used	used	172:175	arg2	method					275:280	an efficient and environmental friendly method	235:280	an efficient and environmental friendly method	235:280	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	1	81	used	used	172:175	arg2	Photocatalysis					141:154	Photocatalysis	141:154	Photocatalysis	141:154	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	6	82	theme	corresponding	1059:1071	arg1	fitting					1079:1085	corresponding model fitting	1059:1085	corresponding model fitting	1059:1085	Adsorption isotherm, thermodynamics, and kinetics with corresponding model fitting were discussed, which suggested that the monolayer and chemical adsorption dominated the adsorption process.					
37001343	8	83	dep	removal	1465:1471	arg1	VI					1461:1462	VI	1461:1462	VI	1461:1462	CuS nanocrystals can enhance the surface charge and light absorbance ability of the composite, and the Cr(VI) removal was governed by electrostatic interaction and photo-induced redox reaction.					
37001343	1	84	theme	efficient	238:246	arg1	Photocatalysis					141:154	Photocatalysis	141:154	Photocatalysis	141:154	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
37001343	1	84	theme	efficient	238:246	arg1	method					275:280	an efficient and environmental friendly method	235:280	an efficient and environmental friendly method	235:280	Photocatalysis has been widely used for the removal of hexavalent chromium from wastewater as an efficient and environmental friendly method.					
35195485	10	0	theme	%	1383:1383	arg1	NaOH					1385:1388	4-10% NaOH	1379:1388	4-10% NaOH	1379:1388	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	6	1	theme	optimal	872:878	arg1	conditions					903:912	optimal operating pretreatment conditions	872:912	optimal operating pretreatment conditions	872:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	1	2	from	crop	185:188	arg1	world					197:201	the world	193:201	the world	193:201	ABSTRACTSugarcane is the most traded crop in the world, with Brazil being the world's largest producer.					
35195485	10	3	theme	methane	1337:1343	arg1	yield					1345:1349	methane yield	1337:1349	methane yield	1337:1349	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	7	4	theme	batch	969:973	arg1	bottles					975:981	84 batch bottles	966:981	84 batch bottles	966:981	The tests were performed in triplicates totalizing 84 batch bottles.					
35195485	1	5	theme	largest	234:240	arg1	producer					242:249	the world's largest producer	222:249	the world's largest producer	222:249	ABSTRACTSugarcane is the most traded crop in the world, with Brazil being the world's largest producer.					
35195485	0	6	theme	alkaline	73:80	arg1	pretreatment					82:93	the alkaline pretreatment	69:93	the alkaline pretreatment	69:93	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	11	7	theme	parameters	1519:1528	arg1	optimization					1486:1497	The optimization	1482:1497	The optimization of the pretreatment parameters	1482:1528	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	11	7	theme	parameters	1519:1528	arg1	key-factor					1551:1560	a key-factor	1549:1560	a key-factor	1549:1560	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	10	8	theme	6-10	1394:1397	arg1	%					1398:1398	%	1398:1398	%	1398:1398	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	11	9	theme	substrates	1616:1625	arg1	digestion					1587:1595	the anaerobic digestion	1573:1595	the anaerobic digestion of lignocellulosic substrates	1573:1625	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	0	10	from	Optimization	0:11	arg1	pretreatment					82:93	the alkaline pretreatment	69:93	the alkaline pretreatment	69:93	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	5	11	theme	mild	597:600	arg1	pretreatment					611:622	mild alkaline pretreatment	597:622	mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours)	597:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	12	theme	alkaline	602:609	arg1	pretreatment					611:622	mild alkaline pretreatment	597:622	mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours)	597:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	11	13	theme	lignocellulosic	1600:1614	arg1	substrates					1616:1625	lignocellulosic substrates	1600:1625	lignocellulosic substrates	1600:1625	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	8	14	theme	pretreated	1071:1080	arg1	samples					1082:1088	the pretreated samples	1067:1088	the pretreated samples with NaOH and KOH	1067:1106	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	9	15	from	%	1174:1174	arg1	NaOH					1163:1166	NaOH	1163:1166	NaOH	1163:1166	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	9	15	from	%	1174:1174	arg1	conditions					1147:1156	The optimized conditions	1133:1156	The optimized conditions	1133:1156	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	3	16	theme	lignocellulosic	398:412	arg1	biomass					414:420	a lignocellulosic biomass	396:420	a lignocellulosic biomass that can be converted into biogas	396:454	SB is a lignocellulosic biomass that can be converted into biogas.					
35195485	3	16	theme	lignocellulosic	398:412	arg1	SB					390:391	SB	390:391	SB	390:391	SB is a lignocellulosic biomass that can be converted into biogas.					
35195485	1	17	theme	traded	178:183	arg1	crop					185:188	the most traded crop	169:188	the most traded crop in the world	169:201	ABSTRACTSugarcane is the most traded crop in the world, with Brazil being the world's largest producer.					
35195485	1	17	theme	traded	178:183	arg1	ABSTRACTSugarcane					148:164	ABSTRACTSugarcane	148:164	ABSTRACTSugarcane	148:164	ABSTRACTSugarcane is the most traded crop in the world, with Brazil being the world's largest producer.					
35195485	0	18	theme	sugarcane	106:114	arg1	bagasse					116:122	sugarcane bagasse	106:122	sugarcane bagasse	106:122	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	6	19	theme	rotatable	804:812	arg1	design					814:819	The central composite rotatable design	782:819	The central composite rotatable design (CCRD)	782:826	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	19	theme	rotatable	804:812	arg1	tool					855:858	statistical tool	843:858	statistical tool to generate optimal operating pretreatment conditions	843:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	19	theme	rotatable	804:812	arg1	CCRD					822:825	CCRD	822:825	CCRD	822:825	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	10	20	theme	statistical	1302:1312	arg1	difference					1314:1323	no statistical difference	1299:1323	no statistical difference	1299:1323	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	8	21	theme	samples	1082:1088	arg1	higher					1125:1130	higher	1125:1130	higher	1125:1130	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	8	21	theme	samples	1082:1088	arg1	BMP					1060:1062	the BMP	1056:1062	the BMP of the pretreated samples with NaOH and KOH	1056:1106	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	6	22	theme	statistical	843:853	arg1	tool					855:858	statistical tool	843:858	statistical tool to generate optimal operating pretreatment conditions	843:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	22	theme	statistical	843:853	arg1	design					814:819	The central composite rotatable design	782:819	The central composite rotatable design (CCRD)	782:826	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	5	23	theme	biochemical	716:726	arg1	BMP					747:749	BMP	747:749	BMP	747:749	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	23	theme	biochemical	716:726	arg1	potential					736:744	the biochemical methane potential	712:744	the biochemical methane potential (BMP) under mesophilic temperature	712:779	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	6	24	theme	composite	794:802	arg1	design					814:819	The central composite rotatable design	782:819	The central composite rotatable design (CCRD)	782:826	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	24	theme	composite	794:802	arg1	tool					855:858	statistical tool	843:858	statistical tool to generate optimal operating pretreatment conditions	843:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	24	theme	composite	794:802	arg1	CCRD					822:825	CCRD	822:825	CCRD	822:825	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	25	theme	pretreatment	890:901	arg1	conditions					903:912	optimal operating pretreatment conditions	872:912	optimal operating pretreatment conditions	872:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	2	26	theme	sugarcane	296:304	arg1	SB					315:316	SB	315:316	SB	315:316	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	26	theme	sugarcane	296:304	arg1	bagasse					306:312	sugarcane bagasse	296:312	sugarcane bagasse (SB) from the entire plant	296:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	10	27	theme	optimized	1464:1472	arg1	points					1474:1479	the specific optimized points	1451:1479	the specific optimized points	1451:1479	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	5	28	theme	methane	728:734	arg1	BMP					747:749	BMP	747:749	BMP	747:749	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	28	theme	methane	728:734	arg1	potential					736:744	the biochemical methane potential	712:744	the biochemical methane potential (BMP) under mesophilic temperature	712:779	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	4	29	theme	pretreatment	486:497	arg1	parameters					507:516	pretreatment process parameters	486:516	pretreatment process parameters	486:516	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	9	30	from	KOH	1180:1182	arg1	NaOH					1163:1166	NaOH	1163:1166	NaOH	1163:1166	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	9	30	from	KOH	1180:1182	arg1	conditions					1147:1156	The optimized conditions	1133:1156	The optimized conditions	1133:1156	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	2	31	from	plant	335:339	arg1	SB					315:316	SB	315:316	SB	315:316	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	31	from	plant	335:339	arg1	%					291:291	up to 28%	283:291	up to 28% of sugarcane bagasse (SB) from the entire plant	283:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	31	from	plant	335:339	arg1	bagasse					306:312	sugarcane bagasse	296:312	sugarcane bagasse (SB) from the entire plant	296:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	9	32	from	KOH	1192:1194	arg1	NaOH					1163:1166	NaOH	1163:1166	NaOH	1163:1166	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	9	32	from	KOH	1192:1194	arg1	conditions					1147:1156	The optimized conditions	1133:1156	The optimized conditions	1133:1156	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	10	33	theme	specific	1455:1462	arg1	points					1474:1479	the specific optimized points	1451:1479	the specific optimized points	1451:1479	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	2	34	theme	energy	371:376	arg1	generation					378:387	energy generation	371:387	energy generation	371:387	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	6	35	theme	operating	880:888	arg1	conditions					903:912	optimal operating pretreatment conditions	872:912	optimal operating pretreatment conditions	872:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	0	36	theme	methane	128:134	arg1	production					136:145	methane production	128:145	methane production	128:145	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	0	37	theme	chemical	16:23	arg1	concentration					34:46	chemical solution concentration	16:46	chemical solution concentration	16:46	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	4	38	theme	parameters	507:516	arg1	optimization					470:481	the optimization	466:481	the optimization of pretreatment process parameters	466:516	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	4	38	theme	parameters	507:516	arg1	essential					521:529	essential	521:529	essential	521:529	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	9	39	theme	8.3	1187:1189	arg1	%					1190:1190	%	1190:1190	%	1190:1190	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	6	40	theme	central	786:792	arg1	design					814:819	The central composite rotatable design	782:819	The central composite rotatable design (CCRD)	782:826	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	40	theme	central	786:792	arg1	tool					855:858	statistical tool	843:858	statistical tool to generate optimal operating pretreatment conditions	843:912	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	6	40	theme	central	786:792	arg1	CCRD					822:825	CCRD	822:825	CCRD	822:825	The central composite rotatable design (CCRD) was applied as statistical tool to generate optimal operating pretreatment conditions.					
35195485	2	41	theme	it	359:360	arg1	it					359:360	it	359:360	it	359:360	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	41	theme	it	359:360	arg1	%					354:354	only 50%	347:354	only 50% of it used for energy generation	347:387	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	5	42	theme	1-12 hours	697:706	arg1	concentrations					652:665	concentrations	652:665	concentrations of 1-10%	652:674	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	42	theme	1-12 hours	697:706	arg1	time					689:692	exposure time	680:692	exposure time of 1-12 hours)	680:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	4	43	theme	process	499:505	arg1	parameters					507:516	pretreatment process parameters	486:516	pretreatment process parameters	486:516	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	11	44	theme	profitable	1720:1729	arg1	process					1731:1737	a more profitable process	1713:1737	a more profitable process	1713:1737	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	9	45	theme	%	1190:1190	arg1	KOH					1192:1194	8.3% KOH	1187:1194	8.3% KOH for 12 hours	1187:1207	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	0	46	theme	concentration	34:46	arg1	Optimization					0:11	Optimization	0:11	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment	0:93	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	8	47	theme	SB	1009:1010	arg1	BMP					988:990	The BMP	984:990	The BMP of the untreated SB	984:1010	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	11	48	theme	pretreatment	1506:1517	arg1	parameters					1519:1528	the pretreatment parameters	1502:1528	the pretreatment parameters	1502:1528	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	0	49	theme	solution	25:32	arg1	concentration					34:46	chemical solution concentration	16:46	chemical solution concentration	16:46	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	5	50	theme	%	674:674	arg1	concentrations					652:665	concentrations	652:665	concentrations of 1-10%	652:674	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	50	theme	%	674:674	arg1	time					689:692	exposure time	680:692	exposure time of 1-12 hours)	680:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	0	51	theme	time	61:64	arg1	Optimization					0:11	Optimization	0:11	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment	0:93	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	5	52	theme	pretreatment	611:622	arg1	effect					587:592	the effect	583:592	the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature	583:779	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	8	53	theme	kg	1042:1043	arg1	VS-1					1045:1048	297-306 LN CH4 kg VS-1	1027:1048	297-306 LN CH4 kg VS-1	1027:1048	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	8	54	theme	CH4	1038:1040	arg1	kg					1042:1043	297-306 LN CH4 kg	1027:1043	297-306 LN CH4 kg VS-1	1027:1048	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	0	55	theme	exposure	52:59	arg1	time					61:64	exposure time	52:64	exposure time	52:64	Optimization of chemical solution concentration and exposure time in the alkaline pretreatment applied to sugarcane bagasse for methane production.					
35195485	5	56	from	effect	587:592	arg1	BMP					747:749	BMP	747:749	BMP	747:749	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	5	56	from	effect	587:592	arg1	potential					736:744	the biochemical methane potential	712:744	the biochemical methane potential (BMP) under mesophilic temperature	712:779	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	8	57	theme	untreated	999:1007	arg1	SB					1009:1010	the untreated SB	995:1010	the untreated SB	995:1010	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	10	58	theme	statistical	1246:1256	arg1	design					1258:1263	the statistical design	1242:1263	the statistical design with CCRD	1242:1273	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	2	59	dep	28	289:290	arg1	to					286:287	to	286:287	to	286:287	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	11	60	theme	dependent	1657:1665	arg1	approach					1688:1695	a less chemically dependent and more sustainable approach	1639:1695	a less chemically dependent and more sustainable approach	1639:1695	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	5	61	theme	SB	627:628	arg1	pretreatment					611:622	mild alkaline pretreatment	597:622	mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours)	597:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	2	62	theme	Sugarcane	252:260	arg1	processing					262:271	Sugarcane processing	252:271	Sugarcane processing	252:271	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	8	63	with	samples	1082:1088	arg1	NaOH					1095:1098	NaOH	1095:1098	NaOH	1095:1098	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	8	63	with	samples	1082:1088	arg1	KOH					1104:1106	KOH	1104:1106	KOH	1104:1106	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	11	64	theme	sustainable	1676:1686	arg1	approach					1688:1695	a less chemically dependent and more sustainable approach	1639:1695	a less chemically dependent and more sustainable approach	1639:1695	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	4	65	theme	scaling	550:556	arg1	up					558:559	its successful scaling up	535:559	its successful scaling up	535:559	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	8	66	theme	LN	1035:1036	arg1	kg					1042:1043	297-306 LN CH4 kg	1027:1043	297-306 LN CH4 kg VS-1	1027:1048	The BMP of the untreated SB varied between 297-306 LN CH4 kg VS-1 while the BMP of the pretreated samples with NaOH and KOH were 19% and 20% higher.					
35195485	9	67	theme	optimized	1137:1145	arg1	NaOH					1163:1166	NaOH	1163:1166	NaOH	1163:1166	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	9	67	theme	optimized	1137:1145	arg1	conditions					1147:1156	The optimized conditions	1133:1156	The optimized conditions	1133:1156	The optimized conditions were NaOH at 7.7% and KOH at 8.3% KOH for 12 hours.					
35195485	2	68	theme	bagasse	306:312	arg1	SB					315:316	SB	315:316	SB	315:316	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	68	theme	bagasse	306:312	arg1	%					291:291	up to 28%	283:291	up to 28% of sugarcane bagasse (SB) from the entire plant	283:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	68	theme	bagasse	306:312	arg1	bagasse					306:312	sugarcane bagasse	296:312	sugarcane bagasse (SB) from the entire plant	296:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	4	69	theme	successful	539:548	arg1	up					558:559	its successful scaling up	535:559	its successful scaling up	535:559	However, the optimization of pretreatment process parameters is essential for its successful scaling up.					
35195485	5	70	theme	mesophilic	758:767	arg1	temperature					769:779	mesophilic temperature	758:779	mesophilic temperature	758:779	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	10	71	theme	%	1398:1398	arg1	KOH					1400:1402	6-10% KOH	1394:1402	6-10% KOH	1394:1402	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	11	72	theme	anaerobic	1577:1585	arg1	digestion					1587:1595	the anaerobic digestion	1573:1595	the anaerobic digestion of lignocellulosic substrates	1573:1625	The optimization of the pretreatment parameters demonstrated to be a key-factor to improve the anaerobic digestion of lignocellulosic substrates, leading to a less chemically dependent and more sustainable approach, while allowing a more profitable process.					
35195485	10	73	theme	4-10	1379:1382	arg1	%					1383:1383	%	1383:1383	%	1383:1383	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	5	74	theme	exposure	680:687	arg1	time					689:692	exposure time	680:692	exposure time of 1-12 hours)	680:707	This study evaluated the effect of mild alkaline pretreatment of SB using NaOH and KOH at concentrations of 1-10% and exposure time of 1-12 hours) on the biochemical methane potential (BMP) under mesophilic temperature.					
35195485	10	75	with	design	1258:1263	arg1	CCRD					1270:1273	CCRD	1270:1273	CCRD	1270:1273	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35195485	2	76	theme	entire	328:333	arg1	plant					335:339	the entire plant	324:339	the entire plant	324:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	2	77	from	%	291:291	arg1	plant					335:339	the entire plant	324:339	the entire plant	324:339	Sugarcane processing generates up to 28% of sugarcane bagasse (SB) from the entire plant, with only 50% of it used for energy generation.					
35195485	10	78	theme	yield	1345:1349	arg1	terms					1328:1332	terms	1328:1332	terms of methane yield	1328:1349	However, the range indicated by the statistical design with CCRD revealed that there was no statistical difference in terms of methane yield when concentrations between 4-10% NaOH and 6-10% KOH during 12 hours were applied, when compared to the specific optimized points.					
35432359	4	0	theme	chemotherapy	626:637	arg1	group					639:643	the cisplatin chemotherapy group	612:643	the cisplatin chemotherapy group	612:643	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	6	1	theme	acid	1292:1295	arg1	esters					1297:1302	fatty acid esters	1286:1302	fatty acid esters of hydroxy fatty acids (FAHFAs)	1286:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	2	2	theme	oxidative	376:384	arg1	damage					386:391	kidney oxidative damage	369:391	kidney oxidative damage	369:391	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	9	3	theme	producing-related	1737:1753	arg1	abundance					1765:1773	FAHFAs producing-related bacterial abundance and FAHFAs levels	1730:1791	abundance	1765:1773	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	5	4	from	creatinine	1158:1167	arg1	levels					1100:1105	the levels	1096:1105	the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group	1096:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	5	theme	control	1202:1208	arg1	group					1210:1214	the normal control group	1191:1214	the normal control group	1191:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	7	6	theme	Lactobacillus	1439:1451	arg1	johnsonii					1483:1491	Lactobacillus johnsonii	1469:1491	Lactobacillus johnsonii	1469:1491	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	7	6	theme	Lactobacillus	1439:1451	arg1	stains					1453:1458	Lactobacillus stains	1439:1458	Lactobacillus stains	1439:1458	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	7	6	theme	Lactobacillus	1439:1451	arg1	reuteri					1511:1517	Lactobacillus reuteri	1497:1517	Lactobacillus reuteri	1497:1517	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	9	7	theme	FAHFAs	1779:1784	arg1	levels					1786:1791	FAHFAs producing-related bacterial abundance and FAHFAs levels	1730:1791	levels	1786:1791	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	4	8	theme	alginate	745:752	arg1	group					770:774	the alginate oligosaccharide group	741:774	the alginate oligosaccharide group	741:774	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	1	9	theme	brown	216:220	arg1	algae					222:226	brown algae	216:226	brown algae	216:226	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	7	10	theme	microbial	1406:1414	arg1	community					1416:1424	the intestinal microbial community	1391:1424	the intestinal microbial community	1391:1424	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	8	11	dep	Lactobacillus	1645:1657	arg1	reuteri					1659:1665	reuteri	1659:1665	reuteri	1659:1665	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	5	12	theme	mice	920:923	arg1	kidneys					925:931	mice kidneys	920:931	mice kidneys	920:931	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	0	13	from	Axis	114:117	arg1	Mice					122:125	Mice	122:125	Mice	122:125	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	6	14	theme	oligosaccharide	1226:1240	arg1	intervention					1242:1253	Alginate oligosaccharide intervention	1217:1253	Alginate oligosaccharide intervention	1217:1253	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	0	15	theme	Cisplatin-Induced	36:52	arg1	Stress					71:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	5	16	theme	oxidative	900:908	arg1	stress					910:915	the oxidative stress	896:915	the oxidative stress of mice kidneys	896:931	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	6	17	theme	fatty	1315:1319	arg1	FAHFAs					1328:1333	FAHFAs	1328:1333	FAHFAs	1328:1333	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	6	17	theme	fatty	1315:1319	arg1	acids					1321:1325	hydroxy fatty acids	1307:1325	hydroxy fatty acids (FAHFAs)	1307:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	5	18	theme	dismutase	988:996	arg1	levels					967:972	the levels	963:972	the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction	963:1091	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	4	19	theme	lipopolysaccharide	803:820	arg1	levels					849:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	5	20	theme	catalase	1005:1012	arg1	levels					967:972	the levels	963:972	the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction	963:1091	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	7	21	theme	Alginate	1337:1344	arg1	oligosaccharide					1346:1360	Alginate oligosaccharide	1337:1360	Alginate oligosaccharide	1337:1360	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	5	22	from	reduction	1083:1091	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	1	23	theme	alginate	185:192	arg1	product					174:180	the depolymerized product	156:180	the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects	156:278	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	1	23	theme	alginate	185:192	arg1	oligosaccharide					137:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	5	24	from	levels	967:972	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	25	from	levels	1807:1812	arg1	tissue					1839:1844	kidney tissue	1832:1844	kidney tissue	1832:1844	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	5	26	theme	malondialdehyde	1110:1124	arg1	levels					1100:1105	the levels	1096:1105	the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group	1096:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	2	27	theme	cisplatin	427:435	arg1	chemotherapy					437:448	cisplatin chemotherapy	427:448	cisplatin chemotherapy	427:448	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	0	28	theme	Oxidative	61:69	arg1	Stress					71:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	5	29	theme	nuclear	1024:1030	arg1	factor					1046:1051	nuclear NF-E2-related factor 2	1024:1053	nuclear NF-E2-related factor 2	1024:1053	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	8	30	theme	FAHFAs	1563:1568	arg1	concentrations					1570:1583	FAHFAs concentrations	1563:1583	FAHFAs concentrations	1563:1583	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	4	31	theme	interleukin-1β	826:839	arg1	levels					849:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	0	32	theme	Alginate	0:7	arg1	Oligosaccharide					9:23	Alginate Oligosaccharide	0:23	Alginate Oligosaccharide	0:23	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	2	33	theme	gut	458:460	arg1	microbiota					462:471	the gut microbiota	454:471	the gut microbiota	454:471	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	0	34	theme	Kidney	54:59	arg1	Stress					71:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Cisplatin-Induced Kidney Oxidative Stress	36:76	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	5	35	theme	serum	1152:1156	arg1	Cr					1170:1171	Cr	1170:1171	Cr	1170:1171	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	35	theme	serum	1152:1156	arg1	creatinine					1158:1167	serum creatinine	1152:1167	serum creatinine (Cr)	1152:1172	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	8	36	theme	Lactobacillus	1617:1629	arg1	abundance					1667:1675	Lactobacillus johnsonii and Lactobacillus reuteri abundance	1617:1675	Lactobacillus johnsonii and Lactobacillus reuteri abundance	1617:1675	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	0	37	theme	Lactobacillus	82:94	arg1	Axis					114:117	Lactobacillus Genus-FAHFAs-Nrf2 Axis	82:117	Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice	82:125	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	3	38	theme	alginate	534:541	arg1	oligosaccharide					543:557	alginate oligosaccharide	534:557	alginate oligosaccharide	534:557	C57BL/6J mice were treated with cisplatin were administered alginate oligosaccharide via gavage for 3 weeks.					
35432359	5	39	theme	renal	1065:1069	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	40	theme	group	1210:1214	arg1	levels					1181:1186	the levels	1177:1186	the levels of the normal control group	1177:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	41	theme	redox	1929:1933	arg1	injury					1935:1940	the renal redox injury	1919:1940	the renal redox injury caused by cisplatin chemotherapy	1919:1973	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	4	42	theme	intragastric	653:664	arg1	administration					666:679	intragastric administration	653:679	intragastric administration of alginate oligosaccharide	653:707	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	2	43	theme	liver	397:401	arg1	inflammation					403:414	liver inflammation	397:414	liver inflammation	397:414	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	1	44	theme	beneficial	254:263	arg1	effects					272:278	beneficial health effects	254:278	beneficial health effects	254:278	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	4	45	dep	improved	729:736	arg1	indicated					777:785	indicated	777:785	indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels	777:854	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	6	46	theme	esters	1297:1302	arg1	concentration					1269:1281	the concentration	1265:1281	the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs)	1265:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	5	47	from	improvement	881:891	arg1	stress					910:915	the oxidative stress	896:915	the oxidative stress of mice kidneys	896:931	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	48	theme	FAHFAs	1730:1735	arg1	abundance					1765:1773	FAHFAs producing-related bacterial abundance and FAHFAs levels	1730:1791	abundance	1765:1773	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	9	49	theme	cisplatin	1952:1960	arg1	chemotherapy					1962:1973	cisplatin chemotherapy	1952:1973	cisplatin chemotherapy	1952:1973	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	4	50	theme	cisplatin	616:624	arg1	group					639:643	the cisplatin chemotherapy group	612:643	the cisplatin chemotherapy group	612:643	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	6	51	theme	fatty	1286:1290	arg1	esters					1297:1302	fatty acid esters	1286:1302	fatty acid esters of hydroxy fatty acids (FAHFAs)	1286:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	5	52	theme	normal	1195:1200	arg1	group					1210:1214	the normal control group	1191:1214	the normal control group	1191:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	53	theme	bacterial	1755:1763	arg1	abundance					1765:1773	FAHFAs producing-related bacterial abundance and FAHFAs levels	1730:1791	abundance	1765:1773	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	2	54	theme	kidney	369:374	arg1	damage					386:391	kidney oxidative damage	369:391	kidney oxidative damage	369:391	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	1	55	theme	natural	197:203	arg1	alginate					185:192	alginate	185:192	alginate	185:192	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	1	55	theme	natural	197:203	arg1	extract					205:211	a natural extract	195:211	a natural extract of brown algae	195:226	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	5	56	from	factor	1046:1051	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	57	dep	accompanied	866:876	arg1	indicated					934:942	indicated	934:942	indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group	934:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	1	58	theme	algae	222:226	arg1	alginate					185:192	alginate	185:192	alginate	185:192	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	1	58	theme	algae	222:226	arg1	extract					205:211	a natural extract	195:211	a natural extract of brown algae	195:226	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	7	59	theme	community	1416:1424	arg1	composition					1376:1386	the composition	1372:1386	the composition of the intestinal microbial community	1372:1424	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	4	60	theme	oligosaccharide	693:707	arg1	administration					666:679	intragastric administration	653:679	intragastric administration of alginate oligosaccharide	653:707	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	5	61	theme	kidneys	925:931	arg1	stress					910:915	the oxidative stress	896:915	the oxidative stress of mice kidneys	896:931	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	7	62	theme	intestinal	1395:1404	arg1	community					1416:1424	the intestinal microbial community	1391:1424	the intestinal microbial community	1391:1424	Alginate oligosaccharide regulated the composition of the intestinal microbial community and promoted Lactobacillus stains, such as Lactobacillus johnsonii and Lactobacillus reuteri.					
35432359	4	63	theme	liver	710:714	arg1	inflammation					716:727	liver inflammation	710:727	liver inflammation	710:727	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	6	64	theme	acids	1321:1325	arg1	esters					1297:1302	fatty acid esters	1286:1302	fatty acid esters of hydroxy fatty acids (FAHFAs)	1286:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	8	65	dep	Lactobacillus	1617:1629	arg1	johnsonii					1631:1639	johnsonii	1631:1639	johnsonii	1631:1639	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	5	66	theme	superoxide	977:986	arg1	dismutase					988:996	superoxide dismutase	977:996	superoxide dismutase (SOD)	977:1002	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	66	theme	superoxide	977:986	arg1	SOD					999:1001	SOD	999:1001	SOD	999:1001	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	67	theme	SOD	1817:1819	arg1	levels					1807:1812	the levels	1803:1812	the levels of SOD and CAT in kidney tissue	1803:1844	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	6	68	theme	hydroxy	1307:1313	arg1	FAHFAs					1328:1333	FAHFAs	1328:1333	FAHFAs	1328:1333	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	6	68	theme	hydroxy	1307:1313	arg1	acids					1321:1325	hydroxy fatty acids	1307:1325	hydroxy fatty acids (FAHFAs)	1307:1334	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	1	69	theme	depolymerized	160:172	arg1	product					174:180	the depolymerized product	156:180	the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects	156:278	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	1	69	theme	depolymerized	160:172	arg1	oligosaccharide					137:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	9	70	theme	CAT	1825:1827	arg1	levels					1807:1812	the levels	1803:1812	the levels of SOD and CAT in kidney tissue	1803:1844	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	8	71	theme	Spearman	1520:1527	arg1	analysis					1529:1536	Spearman analysis	1520:1536	Spearman analysis	1520:1536	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	0	72	theme	Genus-FAHFAs-Nrf2	96:112	arg1	Axis					114:117	Lactobacillus Genus-FAHFAs-Nrf2 Axis	82:117	Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice	82:125	Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.					
35432359	5	73	theme	reduction	1083:1091	arg1	levels					967:972	the levels	963:972	the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction	963:1091	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	74	from	increase	951:958	arg1	levels					967:972	the levels	963:972	the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction	963:1091	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	74	from	increase	951:958	arg1	levels					1100:1105	the levels	1096:1105	the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group	1096:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	9	75	theme	kidney	1832:1837	arg1	tissue					1839:1844	kidney tissue	1832:1844	kidney tissue	1832:1844	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	4	76	theme	oligosaccharide	754:768	arg1	group					770:774	the alginate oligosaccharide group	741:774	the alginate oligosaccharide group	741:774	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	5	77	from	tissue	1071:1076	arg1	levels					967:972	the levels	963:972	the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction	963:1091	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	78	theme	renal	1135:1139	arg1	tissue					1141:1146	renal tissue	1135:1146	renal tissue	1135:1146	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	79	from	levels	1100:1105	arg1	Cr					1170:1171	Cr	1170:1171	Cr	1170:1171	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	79	from	levels	1100:1105	arg1	tissue					1141:1146	renal tissue	1135:1146	renal tissue	1135:1146	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	79	from	levels	1100:1105	arg1	creatinine					1158:1167	serum creatinine	1152:1167	serum creatinine (Cr)	1152:1172	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	4	80	located	observed	600:607	arg1	group					639:643	the cisplatin chemotherapy group	612:643	the cisplatin chemotherapy group	612:643	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	4	80	located	observed	600:607	arg2	that					595:598	that	595:598	that	595:598	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	8	81	theme	concentrations	1570:1583	arg1	members					1552:1558	5 members	1550:1558	5 members of FAHFAs concentrations	1550:1583	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	9	82	theme	MDA	1873:1875	arg1	levels					1863:1868	the levels	1859:1868	the levels of MDA	1859:1875	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	5	83	from	malondialdehyde	1110:1124	arg1	Cr					1170:1171	Cr	1170:1171	Cr	1170:1171	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	83	from	malondialdehyde	1110:1124	arg1	tissue					1141:1146	renal tissue	1135:1146	renal tissue	1135:1146	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	83	from	malondialdehyde	1110:1124	arg1	creatinine					1158:1167	serum creatinine	1152:1167	serum creatinine (Cr)	1152:1172	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	84	from	dismutase	988:996	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	1	85	theme	Alginate	128:135	arg1	product					174:180	the depolymerized product	156:180	the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects	156:278	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	1	85	theme	Alginate	128:135	arg1	oligosaccharide					137:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide	128:151	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
35432359	5	86	from	tissue	1141:1146	arg1	levels					1100:1105	the levels	1096:1105	the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group	1096:1214	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	3	87	theme	C57BL/6J	474:481	arg1	mice					483:486	C57BL/6J mice	474:486	C57BL/6J mice	474:486	C57BL/6J mice were treated with cisplatin were administered alginate oligosaccharide via gavage for 3 weeks.					
35432359	8	88	theme	Lactobacillus	1645:1657	arg1	abundance					1667:1675	Lactobacillus johnsonii and Lactobacillus reuteri abundance	1617:1675	Lactobacillus johnsonii and Lactobacillus reuteri abundance	1617:1675	Spearman analysis showed that 5 members of FAHFAs concentrations were positively correlated with Lactobacillus johnsonii and Lactobacillus reuteri abundance.					
35432359	5	89	from	catalase	1005:1012	arg1	tissue					1071:1076	renal tissue	1065:1076	renal tissue	1065:1076	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	5	90	theme	NF-E2-related	1032:1044	arg1	factor					1046:1051	nuclear NF-E2-related factor 2	1024:1053	nuclear NF-E2-related factor 2	1024:1053	This was accompanied by improvement in the oxidative stress of mice kidneys, indicated by the increase in the levels of superoxide dismutase (SOD), catalase (CAT) and nuclear NF-E2-related factor 2 (Nrf2) in renal tissue, and reduction in the levels of malondialdehyde (MDA) in renal tissue and serum creatinine (Cr) to the levels of the normal control group.					
35432359	6	91	theme	Alginate	1217:1224	arg1	intervention					1242:1253	Alginate oligosaccharide intervention	1217:1253	Alginate oligosaccharide intervention	1217:1253	Alginate oligosaccharide intervention increased the concentration of fatty acid esters of hydroxy fatty acids (FAHFAs).					
35432359	9	92	theme	renal	1923:1927	arg1	injury					1935:1940	the renal redox injury	1919:1940	the renal redox injury caused by cisplatin chemotherapy	1919:1973	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	2	93	theme	alginate	335:342	arg1	oligosaccharides					344:359	alginate oligosaccharides	335:359	alginate oligosaccharides	335:359	Here, we aimed to investigate the mechanism via which alginate oligosaccharides improve kidney oxidative damage and liver inflammation induced by cisplatin chemotherapy via the gut microbiota.					
35432359	4	94	from	reduction	790:798	arg1	levels					849:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	lipopolysaccharide and interleukin-1β (IL-1β) levels	803:854	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	9	95	theme	alginate	1695:1702	arg1	oligosaccharide					1704:1718	alginate oligosaccharide	1695:1718	alginate oligosaccharide	1695:1718	We observed that alginate oligosaccharide increased FAHFAs producing-related bacterial abundance and FAHFAs levels, enhanced the levels of SOD and CAT in kidney tissue, and reduced the levels of MDA via activating Nrf2, thereby ameliorating the renal redox injury caused by cisplatin chemotherapy.					
35432359	4	96	theme	alginate	684:691	arg1	oligosaccharide					693:707	alginate oligosaccharide	684:707	alginate oligosaccharide	684:707	Compared to that observed in the cisplatin chemotherapy group without intragastric administration of alginate oligosaccharide, liver inflammation improved in the alginate oligosaccharide group, indicated by reduction in lipopolysaccharide and interleukin-1β (IL-1β) levels.					
35432359	1	97	theme	health	265:270	arg1	effects					272:278	beneficial health effects	254:278	beneficial health effects	254:278	Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown algae, which is associated with beneficial health effects.					
36876768	0	0	theme	diabetic	93:100	arg1	healing					108:114	diabetic wound healing	93:114	diabetic wound healing	93:114	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	4	1	theme	wound	806:810	arg1	healing					812:818	wound healing	806:818	wound healing	806:818	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	5	2	theme	faster	896:901	arg1	regeneration					903:914	faster regeneration	896:914	faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF	896:1023	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	6	3	theme	Chitosan-based	1037:1050	arg1	hydrogel					1068:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	1	4	theme	major	168:172	arg1	challenge					174:182	a major challenge	166:182	a major challenge in scientific research today	166:211	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	5	5	theme	VEGF	1020:1023	arg1	cells					957:961	fewer inflammatory cells	938:961	fewer inflammatory cells	938:961	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	5	theme	VEGF	1020:1023	arg1	deposition					978:987	more collagen deposition	964:987	more collagen deposition	964:987	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	5	theme	VEGF	1020:1023	arg1	tissue					930:935	epithelial tissue	919:935	epithelial tissue	919:935	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	5	theme	VEGF	1020:1023	arg1	level					1011:1015	higher expression level	993:1015	higher expression level	993:1015	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	6	6	contain	has	1077:1079	arg2	dressing					1114:1121	a dressing	1112:1121	a dressing for promoting the healing of diabetic wounds	1112:1166	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	6	6	contain	has	1077:1079	arg1	hydrogel					1068:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	6	6	contain	has	1077:1079	arg2	potential					1099:1107	great application potential	1081:1107	great application potential	1081:1107	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	3	7	theme	excellent	593:601	arg1	efficiency					616:625	excellent self-healing efficiency	593:625	excellent self-healing efficiency	593:625	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	3	8	theme	good	628:631	arg1	cytocompatibility					633:649	good cytocompatibility	628:649	good cytocompatibility	628:649	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	4	9	theme	composite	698:706	arg1	hydrogels					708:716	the composite hydrogels	694:716	the composite hydrogels	694:716	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	0	10	theme	wound	102:106	arg1	healing					108:114	diabetic wound healing	93:114	diabetic wound healing	93:114	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	3	11	theme	mechanical	557:566	arg1	strength					568:575	strong mechanical strength	550:575	strong mechanical strength	550:575	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	5	12	theme	more	964:967	arg1	deposition					978:987	more collagen deposition	964:987	more collagen deposition	964:987	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	1	13	theme	scientific	187:196	arg1	today					207:211	scientific research today	187:211	scientific research today	187:211	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	5	14	theme	fewer	938:942	arg1	cells					957:961	fewer inflammatory cells	938:961	fewer inflammatory cells	938:961	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	15	theme	higher	993:998	arg1	level					1011:1015	higher expression level	993:1015	higher expression level	993:1015	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	0	16	theme	self-healing	11:22	arg1	hydrogel					55:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel	0:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing	0:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	2	17	theme	Schiff	434:439	arg1	base					441:444	Schiff base	434:444	Schiff base	434:444	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	0	18	theme	Injectable	0:9	arg1	hydrogel					55:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel	0:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing	0:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	4	19	dep	cells	735:739	arg1	proliferation					755:767	proliferation	755:767	proliferation	755:767	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	4	19	dep	cells	735:739	arg1	migration					741:749	migration	741:749	migration	741:749	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	4	19	dep	cells	735:739	arg1	cells					735:739	cells migration and proliferation	735:767	cells migration and proliferation	735:767	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	1	20	theme	research	198:205	arg1	today					207:211	scientific research today	187:211	scientific research today	187:211	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	0	21	theme	POSS-PEG	39:46	arg1	hydrogel					55:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel	0:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing	0:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	2	22	attach	crosslinked	356:366	arg3	base					441:444	Schiff base	434:444	Schiff base	434:444	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	5	23	theme	inflammatory	944:955	arg1	cells					957:961	fewer inflammatory cells	938:961	fewer inflammatory cells	938:961	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	2	24	theme	POSS-PEG	480:487	arg1	hydrogels					496:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	25	theme	hybrid	489:494	arg1	hydrogels					496:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	3	26	theme	antibacterial	655:667	arg1	properties					669:678	antibacterial properties	655:678	antibacterial properties	655:678	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	6	27	theme	POSS-PEG	1052:1059	arg1	hydrogel					1068:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	2	28	theme	Chitosan-based	465:478	arg1	hydrogels					496:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	Chitosan-based POSS-PEG hybrid hydrogels	465:504	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	4	29	theme	diabetic	823:830	arg1	mice					832:835	diabetic mice	823:835	diabetic mice	823:835	Furthermore, the composite hydrogels could accelerate cells migration and proliferation, as expected by remarkably promoting wound healing in diabetic mice.					
36876768	5	30	theme	collagen	969:976	arg1	deposition					978:987	more collagen deposition	964:987	more collagen deposition	964:987	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	31	theme	level	1011:1015	arg1	regeneration					903:914	faster regeneration	896:914	faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF	896:1023	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	3	32	theme	designed	511:518	arg1	hydrogels					530:538	The designed composite hydrogels	507:538	The designed composite hydrogels	507:538	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	0	33	theme	hybrid	48:53	arg1	hydrogel					55:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel	0:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing	0:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	6	34	theme	application	1087:1097	arg1	potential					1099:1107	great application potential	1081:1107	great application potential	1081:1107	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	6	34	theme	application	1087:1097	arg1	dressing					1114:1121	a dressing	1112:1121	a dressing for promoting the healing of diabetic wounds	1112:1166	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	5	35	theme	expression	1000:1009	arg1	level					1011:1015	higher expression level	993:1015	higher expression level	993:1015	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	2	36	theme	octafunctionalized	249:266	arg1	POSS					268:271	A star-like eight-arm cross-linker octafunctionalized POSS	214:271	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	214:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	3	37	theme	composite	520:528	arg1	hydrogels					530:538	The designed composite hydrogels	507:538	The designed composite hydrogels	507:538	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	0	38	theme	wound	67:71	arg1	dressing					73:80	wound dressing	67:80	wound dressing	67:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	6	39	theme	great	1081:1085	arg1	potential					1099:1107	great application potential	1081:1107	great application potential	1081:1107	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	6	39	theme	great	1081:1085	arg1	dressing					1114:1121	a dressing	1112:1121	a dressing for promoting the healing of diabetic wounds	1112:1166	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	5	40	theme	cells	957:961	arg1	regeneration					903:914	faster regeneration	896:914	faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF	896:1023	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	2	41	theme	cross-linker	236:247	arg1	POSS					268:271	A star-like eight-arm cross-linker octafunctionalized POSS	214:271	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	214:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	42	theme	chloride	405:412	arg1	HACC					424:427	HACC	424:427	HACC	424:427	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	42	theme	chloride	405:412	arg1	chitosan					414:421	hydroxypropyltrimethyl ammonium chloride chitosan	373:421	hydroxypropyltrimethyl ammonium chloride chitosan (HACC)	373:428	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	5	43	theme	tissue	930:935	arg1	regeneration					903:914	faster regeneration	896:914	faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF	896:1023	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	2	44	theme	star-like	216:224	arg1	POSS					268:271	A star-like eight-arm cross-linker octafunctionalized POSS	214:271	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	214:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	45	theme	eight-arm	226:234	arg1	POSS					268:271	A star-like eight-arm cross-linker octafunctionalized POSS	214:271	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	214:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	46	theme	ammonium	396:403	arg1	chloride					405:412	hydroxypropyltrimethyl ammonium chloride	373:412	hydroxypropyltrimethyl ammonium chloride chitosan (HACC)	373:428	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	47	theme	glycol	313:318	arg1	POSS					268:271	A star-like eight-arm cross-linker octafunctionalized POSS	214:271	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	214:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	6	48	theme	wounds	1161:1166	arg1	healing					1141:1147	the healing	1137:1147	the healing of diabetic wounds	1137:1166	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	2	49	theme	hydroxypropyltrimethyl	373:394	arg1	chloride					405:412	hydroxypropyltrimethyl ammonium chloride	373:412	hydroxypropyltrimethyl ammonium chloride chitosan (HACC)	373:428	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	50	theme	polyethylene	300:311	arg1	POSS-PEG-CHO					321:332	POSS-PEG-CHO	321:332	POSS-PEG-CHO	321:332	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	50	theme	polyethylene	300:311	arg1	glycol					313:318	benzaldehyde-terminated polyethylene glycol	276:318	benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	276:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	1	51	theme	diabetic	142:149	arg1	wounds					151:156	diabetic wounds	142:156	diabetic wounds	142:156	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	3	52	theme	strong	550:555	arg1	strength					568:575	strong mechanical strength	550:575	strong mechanical strength	550:575	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36876768	5	53	theme	composite	866:874	arg1	hydrogels					876:884	the composite hydrogels	862:884	the composite hydrogels	862:884	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	5	54	theme	deposition	978:987	arg1	regeneration					903:914	faster regeneration	896:914	faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF	896:1023	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	2	55	theme	benzaldehyde-terminated	276:298	arg1	POSS-PEG-CHO					321:332	POSS-PEG-CHO	321:332	POSS-PEG-CHO	321:332	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	2	55	theme	benzaldehyde-terminated	276:298	arg1	glycol					313:318	benzaldehyde-terminated polyethylene glycol	276:318	benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO)	276:333	A star-like eight-arm cross-linker octafunctionalized POSS of benzaldehyde-terminated polyethylene glycol (POSS-PEG-CHO) was synthesized, and crosslinked with hydroxypropyltrimethyl ammonium chloride chitosan (HACC) via Schiff base reaction to obtain Chitosan-based POSS-PEG hybrid hydrogels.					
36876768	1	56	theme	wounds	151:156	arg1	healing					131:137	the healing	127:137	the healing of diabetic wounds	127:156	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	6	57	theme	diabetic	1152:1159	arg1	wounds					1161:1166	diabetic wounds	1152:1166	diabetic wounds	1152:1166	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	5	58	theme	epithelial	919:928	arg1	tissue					930:935	epithelial tissue	919:935	epithelial tissue	919:935	The wounds treated with the composite hydrogels displayed faster regeneration of epithelial tissue, fewer inflammatory cells, more collagen deposition and higher expression level of VEGF.					
36876768	6	59	theme	hybrid	1061:1066	arg1	hydrogel					1068:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Chitosan-based POSS-PEG hybrid hydrogel	1037:1075	Therefore, Chitosan-based POSS-PEG hybrid hydrogel has great application potential as a dressing for promoting the healing of diabetic wounds.					
36876768	0	60	theme	chitosan-based	24:37	arg1	hydrogel					55:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel	0:62	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing	0:80	Injectable self-healing chitosan-based POSS-PEG hybrid hydrogel as wound dressing to promote diabetic wound healing.					
36876768	1	61	from	challenge	174:182	arg1	today					207:211	scientific research today	187:211	scientific research today	187:211	Promoting the healing of diabetic wounds remains a major challenge in scientific research today.					
36876768	3	62	theme	self-healing	603:614	arg1	efficiency					616:625	excellent self-healing efficiency	593:625	excellent self-healing efficiency	593:625	The designed composite hydrogels exhibited strong mechanical strength, injectability, excellent self-healing efficiency, good cytocompatibility and antibacterial properties.					
36615232	0	0	theme	Experimental	102:113	arg1	Design					115:120	Experimental Design	102:120	Experimental Design	102:120	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	7	1	theme	ICs	1159:1161	arg1	properties					1141:1150	the physicochemical properties	1121:1150	the physicochemical properties of the ICs	1121:1161	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	7	2	theme	TGA	1062:1064	arg1	experiments					1083:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	6	3	theme	central	949:955	arg1	design					967:972	a central composite design	947:972	a central composite design for optimization of the parameters (step 2, optimizing the key parameters)	947:1047	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	13	4	theme	molecular	2011:2019	arg1	complexation					2031:2042	molecular inclusion complexation	2011:2042	molecular inclusion complexation	2011:2042	Furthermore, molecular modeling was used to study the mechanisms involved in molecular inclusion complexation.					
36615232	4	5	theme	IC	562:563	arg1	process					575:581	the IC formation process	558:581	the IC formation process	558:581	Furthermore, the IC formation process was investigated using experimental techniques and molecular modeling.					
36615232	8	6	theme	molecular	1262:1270	arg1	docking					1272:1278	molecular docking	1262:1278	molecular docking	1262:1278	In addition, the interaction between EO and β-CD was further investigated using phase solubility, molecular docking, and molecular simulation studies.					
36615232	6	7	dep	design	891:896	arg1	identifying					907:917	identifying	907:917	identifying key parameters	907:932	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	3	8	theme	current	381:387	arg1	study					389:393	the current study	377:393	the current study	377:393	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	7	9	theme	SEM	1050:1052	arg1	experiments					1083:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	5	10	theme	major	658:662	arg1	carvacrol					715:723	carvacrol	715:723	carvacrol	715:723	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	5	10	theme	major	658:662	arg1	components					664:673	The major components	654:673	The major components of M. Chinensis 'Jiangxiangru' EOs	654:708	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	6	11	theme	composite	957:965	arg1	design					967:972	a central composite design	947:972	a central composite design for optimization of the parameters (step 2, optimizing the key parameters)	947:1047	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	3	12	theme	study	389:393	arg1	aim					370:372	the aim	366:372	the aim of the current study	366:393	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	6	13	theme	Plackett-Burman	875:889	arg1	design					891:896	a Plackett-Burman design	873:896	a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters)	873:1047	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	12	14	theme	comprehensive	1755:1767	arg1	methodology					1769:1779	a comprehensive methodology	1753:1779	a comprehensive methodology	1753:1779	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	13	15	theme	molecular	1947:1955	arg1	modeling					1957:1964	molecular modeling	1947:1964	molecular modeling	1947:1964	Furthermore, molecular modeling was used to study the mechanisms involved in molecular inclusion complexation.					
36615232	5	16	with	IC	767:768	arg1	β-CD					775:778	β-CD	775:778	β-CD	775:778	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	4	17	theme	formation	565:573	arg1	process					575:581	the IC formation process	558:581	the IC formation process	558:581	Furthermore, the IC formation process was investigated using experimental techniques and molecular modeling.					
36615232	7	18	theme	physicochemical	1125:1139	arg1	properties					1141:1150	the physicochemical properties	1121:1150	the physicochemical properties of the ICs	1121:1161	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	11	19	theme	dynamics	1624:1631	arg1	simulation					1633:1642	molecular docking and dynamics simulation	1602:1642	molecular docking and dynamics simulation	1602:1642	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	3	20	dep	solubility	414:423	arg1	the					410:412	the	410:412	the	410:412	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	8	21	theme	simulation	1295:1304	arg1	studies					1306:1312	molecular simulation studies	1285:1312	molecular simulation studies	1285:1312	In addition, the interaction between EO and β-CD was further investigated using phase solubility, molecular docking, and molecular simulation studies.					
36615232	9	22	theme	EO	1400:1401	arg1	efficiency					1365:1374	the optimal encapsulation efficiency	1339:1374	the optimal encapsulation efficiency	1339:1374	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	9	22	theme	EO	1400:1401	arg1	capacity					1388:1395	loading capacity	1380:1395	loading capacity	1380:1395	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	9	22	theme	EO	1400:1401	arg1	%					1424:1424	86.17%	1419:1424	86.17%	1419:1424	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	3	23	theme	Chinensis	452:460	arg1	EO					477:478	the Mosla Chinensis (M. Chinensis) EO	442:478	the Mosla Chinensis (M. Chinensis) EO	442:478	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	0	24	theme	Molecular	126:134	arg1	Modeling					136:143	Molecular Modeling	126:143	Molecular Modeling	126:143	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	6	25	dep	parameters	998:1007	arg1	optimizing					1018:1027	optimizing	1018:1027	optimizing the key parameters	1018:1046	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	9	26	theme	encapsulation	1351:1363	arg1	efficiency					1365:1374	the optimal encapsulation efficiency	1339:1374	the optimal encapsulation efficiency	1339:1374	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	9	26	theme	encapsulation	1351:1363	arg1	%					1424:1424	86.17%	1419:1424	86.17%	1419:1424	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	8	27	theme	molecular	1285:1293	arg1	studies					1306:1312	molecular simulation studies	1285:1312	molecular simulation studies	1285:1312	In addition, the interaction between EO and β-CD was further investigated using phase solubility, molecular docking, and molecular simulation studies.					
36615232	6	28	theme	key	1033:1035	arg1	parameters					1037:1046	the key parameters	1029:1046	the key parameters	1029:1046	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	11	29	theme	docking	1612:1618	arg1	simulation					1633:1642	molecular docking and dynamics simulation	1602:1642	molecular docking and dynamics simulation	1602:1642	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	13	30	theme	inclusion	2021:2029	arg1	complexation					2031:2042	molecular inclusion complexation	2011:2042	molecular inclusion complexation	2011:2042	Furthermore, molecular modeling was used to study the mechanisms involved in molecular inclusion complexation.					
36615232	1	31	theme	medicinal	195:203	arg1	plants					205:210	medicinal plants	195:210	medicinal plants	195:210	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	12	32	theme	optimization	1878:1889	arg1	experiments					1891:1901	two-step optimization experiments	1869:1901	two-step optimization experiments	1869:1901	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	6	33	dep	optimizing	1018:1027	arg1	step					1010:1013	step 2	1010:1015	step 2	1010:1015	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	9	34	theme	optimal	1343:1349	arg1	efficiency					1365:1374	the optimal encapsulation efficiency	1339:1374	the optimal encapsulation efficiency	1339:1374	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	9	34	theme	optimal	1343:1349	arg1	%					1424:1424	86.17%	1419:1424	86.17%	1419:1424	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	5	35	theme	ultrasonication	804:818	arg1	method					820:825	the ultrasonication method	800:825	the ultrasonication method	800:825	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	12	36	with	ICs	1913:1915	arg1	β-CD					1928:1931	β-CD	1928:1931	β-CD	1928:1931	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	12	37	theme	multivariate	1832:1843	arg1	conditions					1845:1854	multivariate conditions	1832:1854	multivariate conditions	1832:1854	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	2	38	theme	application	332:342	arg1	potential					344:352	their application potential	326:352	their application potential	326:352	However, their low water solubility and volatility substantially limit their application potential.					
36615232	6	39	dep	identifying	907:917	arg1	step					899:902	step 1	899:904	step 1	899:904	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	9	40	theme	loading	1380:1386	arg1	capacity					1388:1395	loading capacity	1380:1395	loading capacity	1380:1395	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	3	41	theme	EO	477:478	arg1	stability					429:437	stability	429:437	stability	429:437	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	3	41	theme	EO	477:478	arg1	solubility					414:423	solubility	414:423	solubility	414:423	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	0	42	theme	Chinensis	57:65	arg1	Complexes					91:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	3	43	theme	inclusion	494:502	arg1	IC					513:514	IC	513:514	IC	513:514	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	3	43	theme	inclusion	494:502	arg1	complex					504:510	an inclusion complex	491:510	an inclusion complex (IC)	491:515	Therefore, the aim of the current study was to improve the solubility and stability of the Mosla Chinensis (M. Chinensis) EO by forming an inclusion complex (IC) with β-cyclodextrin (β-CD).					
36615232	5	44	theme	EOs	706:708	arg1	carvacrol					715:723	carvacrol	715:723	carvacrol	715:723	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	5	44	theme	EOs	706:708	arg1	components					664:673	The major components	654:673	The major components of M. Chinensis 'Jiangxiangru' EOs	654:708	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	1	45	attach	isolated	181:188	arg1	plants					205:210	medicinal plants	195:210	medicinal plants	195:210	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	45	attach	isolated	181:188	arg2	EOs					162:164	EOs	162:164	EOs	162:164	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	45	attach	isolated	181:188	arg2	oils					156:159	Essential oils	146:159	Essential oils (EOs)	146:165	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	46	theme	various	224:230	arg1	properties					243:252	various biological properties	224:252	various biological properties	224:252	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	0	47	theme	β-Cyclodextrin/Mosla	36:55	arg1	Complexes					91:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	12	48	theme	two-step	1869:1876	arg1	experiments					1891:1901	two-step optimization experiments	1869:1901	two-step optimization experiments	1869:1901	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	9	49	from	efficiency	1365:1374	arg1	ICs					1410:1412	the ICs	1406:1412	the ICs	1406:1412	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	6	50	theme	Multivariable	828:840	arg1	optimization					842:853	Multivariable optimization	828:853	Multivariable optimization	828:853	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	1	51	theme	biological	232:241	arg1	properties					243:252	various biological properties	224:252	various biological properties	224:252	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	0	52	theme	Oil	77:79	arg1	Complexes					91:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	5	53	dep	Chinensis	681:689	arg1	Jiangxiangru					692:703	Jiangxiangru	692:703	Jiangxiangru	692:703	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	10	54	theme	properties	1478:1487	arg1	Results					1451:1457	Results	1451:1457	Results of physicochemical properties	1451:1487	Results of physicochemical properties were different after being encapsulated, indicating that the ICs had been successfully fabricated.					
36615232	11	55	theme	molecular	1602:1610	arg1	docking					1612:1618	molecular docking and dynamics	1602:1631	docking	1612:1618	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	0	56	theme	Essential	67:75	arg1	Complexes					91:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	11	57	theme	noncovalent	1712:1722	arg1	interactions					1724:1735	noncovalent interactions	1712:1735	noncovalent interactions	1712:1735	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	10	58	theme	physicochemical	1462:1476	arg1	properties					1478:1487	physicochemical properties	1462:1487	physicochemical properties	1462:1487	Results of physicochemical properties were different after being encapsulated, indicating that the ICs had been successfully fabricated.					
36615232	12	59	theme	EO	1920:1921	arg1	ICs					1913:1915	ICs	1913:1915	ICs of EO with β-CD	1913:1931	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	1	60	theme	Essential	146:154	arg1	oils					156:159	Essential oils	146:159	Essential oils (EOs)	146:165	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	60	theme	Essential	146:154	arg1	EOs					162:164	EOs	162:164	EOs	162:164	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	5	61	theme	Chinensis	681:689	arg1	EOs					706:708	M. Chinensis 'Jiangxiangru' EOs	678:708	M. Chinensis 'Jiangxiangru' EOs	678:708	The major components of M. Chinensis 'Jiangxiangru' EOs were carvacrol, thymol, o-cymene, and terpinene, and its IC with β-CD were prepared using the ultrasonication method.					
36615232	11	62	theme	EO	1683:1684	arg1	carvacrol					1697:1705	carvacrol	1697:1705	carvacrol	1697:1705	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	11	62	theme	EO	1683:1684	arg1	component					1686:1694	the EO component	1679:1694	the EO component (carvacrol)	1679:1706	Additionally, molecular docking and dynamics simulation showed that β-CD could encapsulate the EO component (carvacrol) via noncovalent interactions.					
36615232	7	63	theme	dissolution	1071:1081	arg1	experiments					1083:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	8	64	theme	phase	1244:1248	arg1	solubility					1250:1259	phase solubility	1244:1259	phase solubility	1244:1259	In addition, the interaction between EO and β-CD was further investigated using phase solubility, molecular docking, and molecular simulation studies.					
36615232	6	65	theme	parameters	998:1007	arg1	optimization					978:989	optimization	978:989	optimization of the parameters (step 2, optimizing the key parameters)	978:1047	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36615232	12	66	theme	key	1811:1813	arg1	parameters					1815:1824	key parameters	1811:1824	key parameters	1811:1824	In conclusion, a comprehensive methodology was developed for determining key parameters under multivariate conditions by utilizing two-step optimization experiments to obtain ICs of EO with β-CD.					
36615232	1	67	contain	possess	216:222	arg1	oils					156:159	Essential oils	146:159	Essential oils (EOs)	146:165	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	67	contain	possess	216:222	arg2	properties					243:252	various biological properties	224:252	various biological properties	224:252	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	1	67	contain	possess	216:222	arg1	EOs					162:164	EOs	162:164	EOs	162:164	Essential oils (EOs) are primarily isolated from medicinal plants and possess various biological properties.					
36615232	2	68	theme	water	274:278	arg1	solubility					280:289	their low water solubility	264:289	their low water solubility	264:289	However, their low water solubility and volatility substantially limit their application potential.					
36615232	7	69	theme	FT-IR	1055:1059	arg1	experiments					1083:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments	1050:1093	SEM, FT-IR, TGA, and dissolution experiments were performed to analyze the physicochemical properties of the ICs.					
36615232	0	70	theme	Complexes	91:99	arg1	Characterization					16:31	Characterization	16:31	Characterization	16:31	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	0	70	theme	Complexes	91:99	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	4	71	theme	molecular	634:642	arg1	modeling					644:651	molecular modeling	634:651	molecular modeling	634:651	Furthermore, the IC formation process was investigated using experimental techniques and molecular modeling.					
36615232	2	72	theme	low	270:272	arg1	solubility					280:289	their low water solubility	264:289	their low water solubility	264:289	However, their low water solubility and volatility substantially limit their application potential.					
36615232	13	73	used	used	1970:1973	arg2	modeling					1957:1964	molecular modeling	1947:1964	molecular modeling	1947:1964	Furthermore, molecular modeling was used to study the mechanisms involved in molecular inclusion complexation.					
36615232	4	74	theme	experimental	606:617	arg1	techniques					619:628	experimental techniques	606:628	experimental techniques	606:628	Furthermore, the IC formation process was investigated using experimental techniques and molecular modeling.					
36615232	0	75	theme	Inclusion	81:89	arg1	Complexes					91:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes	36:99	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	0	76	dep	Fabrication	0:10	arg1	Design					115:120	Experimental Design	102:120	Experimental Design	102:120	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	0	76	dep	Fabrication	0:10	arg1	Modeling					136:143	Molecular Modeling	126:143	Molecular Modeling	126:143	Fabrication and Characterization of β-Cyclodextrin/Mosla Chinensis Essential Oil Inclusion Complexes: Experimental Design and Molecular Modeling.					
36615232	9	77	from	capacity	1388:1395	arg1	ICs					1410:1412	the ICs	1406:1412	the ICs	1406:1412	The results showed that the optimal encapsulation efficiency and loading capacity of EO in the ICs were 86.17% and 8.92%, respectively.					
36615232	6	78	theme	key	919:921	arg1	parameters					923:932	key parameters	919:932	key parameters	919:932	Multivariable optimization was studied using a Plackett-Burman design (step 1, identifying key parameters) followed by a central composite design for optimization of the parameters (step 2, optimizing the key parameters).					
36972830	0	0	theme	Brønsted-Lewis	87:100	arg1	sites					112:116	Brønsted-Lewis dual acid sites	87:116	Brønsted-Lewis dual acid sites for efficient conversion of cellulose	87:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	3	1	theme	cellulose	654:662	arg1	conversion					640:649	the selective catalytic conversion	616:649	the selective catalytic conversion of cellulose	616:662	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	8	2	theme	study	1261:1265	arg1	results					1245:1251	The results	1241:1251	The results of this study	1241:1265	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	5	3	theme	Brønsted-Lewis	908:921	arg1	sites					933:937	Brønsted-Lewis dual acid sites	908:937	Brønsted-Lewis dual acid sites	908:937	This process provided the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites and improved its stability and recoverability.					
36972830	2	4	theme	precursor	493:501	arg1	calcination					441:451	one-step calcination	432:451	one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3)	432:530	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	3	5	theme	catalytic	630:638	arg1	conversion					640:649	the selective catalytic conversion	616:649	the selective catalytic conversion of cellulose	616:662	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	2	6	theme	acid	358:361	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	6	7	theme	reaction	1038:1045	arg1	conditions					1047:1056	optimal reaction conditions	1030:1056	optimal reaction conditions (180 °C, 4 h)	1030:1070	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	0	8	theme	acid	107:110	arg1	sites					112:116	Brønsted-Lewis dual acid sites	87:116	Brønsted-Lewis dual acid sites for efficient conversion of cellulose	87:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	4	9	theme	functional	838:847	arg1	groups					849:854	oxygen-containing functional groups	820:854	oxygen-containing functional groups	820:854	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	6	10	used	used	1019:1022	arg2	catalyst					1006:1013	the MA-Al/N-BC catalyst	991:1013	the MA-Al/N-BC catalyst	991:1013	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	2	11	theme	stable	303:308	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	5	12	theme	acid	928:931	arg1	sites					933:937	Brønsted-Lewis dual acid sites	908:937	Brønsted-Lewis dual acid sites	908:937	This process provided the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites and improved its stability and recoverability.					
36972830	0	13	theme	dual	102:105	arg1	sites					112:116	Brønsted-Lewis dual acid sites	87:116	Brønsted-Lewis dual acid sites for efficient conversion of cellulose	87:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	3	14	theme	levulinic	675:683	arg1	LA					691:692	LA	691:692	LA	691:692	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	3	14	theme	levulinic	675:683	arg1	acid					685:688	levulinic acid	675:688	levulinic acid (LA)	675:693	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	4	15	theme	oxygen-containing	820:836	arg1	groups					849:854	oxygen-containing functional groups	820:854	oxygen-containing functional groups	820:854	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	4	16	theme	MA	696:697	arg1	treatment					699:707	MA treatment	696:707	MA treatment	696:707	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	7	17	theme	catalytic	1196:1204	arg1	conversion					1206:1215	catalytic conversion	1196:1215	catalytic conversion of other carbohydrates	1196:1238	Additionally, it also showed high activity for catalytic conversion of other carbohydrates.					
36972830	6	18	theme	cellulose	1087:1095	arg1	rate					1108:1111	a cellulose conversion rate	1085:1111	a cellulose conversion rate of 93.1 %	1085:1121	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	4	19	theme	N-BC	788:791	arg1	support					793:799	the N-BC support	784:799	the N-BC support	784:799	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	4	20	theme	uniform	718:724	arg1	dispersion					726:735	uniform dispersion	718:735	uniform dispersion	718:735	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	5	21	theme	MA-Al/N-BC	883:892	arg1	catalyst					894:901	the MA-Al/N-BC catalyst	879:901	the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites	879:937	This process provided the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites and improved its stability and recoverability.					
36972830	1	22	theme	sustainable	176:186	arg1	catalysts					188:196	sustainable catalysts	176:196	sustainable catalysts for the efficient conversion of biomass to desirable chemicals	176:259	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	2	23	theme	-treated	484:491	arg1	precursor					493:501	a mechanical activation (MA)-treated precursor	456:501	a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3)	456:530	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	6	24	theme	MA-Al/N-BC	995:1004	arg1	catalyst					1006:1013	the MA-Al/N-BC catalyst	991:1013	the MA-Al/N-BC catalyst	991:1013	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	1	25	theme	catalysts	188:196	arg1	development					161:171	The development	157:171	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals	157:259	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	1	25	theme	catalysts	188:196	arg1	significant					264:274	significant	264:274	significant	264:274	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	6	26	dep	conditions	1047:1056	arg1	4 h					1067:1069	4 h	1067:1069	4 h	1067:1069	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	6	26	dep	conditions	1047:1056	arg1	180 °C					1059:1064	180 °C	1059:1064	180 °C	1059:1064	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	2	27	theme	acid	397:400	arg1	sites					402:406	Brønsted-Lewis dual acid sites	377:406	Brønsted-Lewis dual acid sites	377:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	28	theme	mechanical	458:467	arg1	precursor					493:501	a mechanical activation (MA)-treated precursor	456:501	a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3)	456:530	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	29	theme	BC	319:320	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	30	theme	dual	392:395	arg1	sites					402:406	Brønsted-Lewis dual acid sites	377:406	Brønsted-Lewis dual acid sites	377:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	0	31	theme	stable	18:23	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	4	32	theme	components	770:779	arg1	dispersion					726:735	uniform dispersion	718:735	uniform dispersion	718:735	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	4	32	theme	components	770:779	arg1	embedding					748:756	stable embedding	741:756	stable embedding	741:756	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	5	33	theme	dual	923:926	arg1	sites					933:937	Brønsted-Lewis dual acid sites	908:937	Brønsted-Lewis dual acid sites	908:937	This process provided the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites and improved its stability and recoverability.					
36972830	8	34	theme	biomass-derived	1328:1342	arg1	chemicals					1344:1352	sustainable biomass-derived chemicals	1316:1352	sustainable biomass-derived chemicals	1316:1352	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	1	35	theme	efficient	206:214	arg1	conversion					216:225	the efficient conversion	202:225	the efficient conversion of biomass to desirable chemicals	202:259	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	3	36	theme	as-prepared	537:547	arg1	N-BC					561:564	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	5	37	with	catalyst	894:901	arg1	sites					933:937	Brønsted-Lewis dual acid sites	908:937	Brønsted-Lewis dual acid sites	908:937	This process provided the MA-Al/N-BC catalyst with Brønsted-Lewis dual acid sites and improved its stability and recoverability.					
36972830	0	38	theme	efficient	122:130	arg1	conversion					132:141	efficient conversion	122:141	efficient conversion of cellulose	122:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	8	39	theme	eco-friendly	1384:1395	arg1	catalysts					1397:1405	stable and eco-friendly catalysts	1373:1405	stable and eco-friendly catalysts	1373:1405	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	2	40	theme	biochar	310:316	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	41	theme	one-step	432:439	arg1	calcination					441:451	one-step calcination	432:451	one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3)	432:530	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	0	42	theme	amorphous	43:51	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	0	43	theme	cellulose	146:154	arg1	conversion					132:141	efficient conversion	122:141	efficient conversion of cellulose	122:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	7	44	theme	high	1178:1181	arg1	activity					1183:1190	high activity	1178:1190	high activity for catalytic conversion of other carbohydrates	1178:1238	Additionally, it also showed high activity for catalytic conversion of other carbohydrates.					
36972830	4	45	theme	Al-based	761:768	arg1	components					770:779	Al-based components	761:779	Al-based components	761:779	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	3	46	dep	N-BC	561:564	arg1	MA-Al/N-BC					591:600	MA-Al/N-BC	591:600	MA-Al/N-BC	591:600	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	3	46	dep	N-BC	561:564	arg1	composite					580:588	Al composite	577:588	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	7	47	theme	other	1220:1224	arg1	carbohydrates					1226:1238	other carbohydrates	1220:1238	other carbohydrates	1220:1238	Additionally, it also showed high activity for catalytic conversion of other carbohydrates.					
36972830	0	48	theme	biochar-supported	25:41	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	8	49	theme	sustainable	1316:1326	arg1	chemicals					1344:1352	sustainable biomass-derived chemicals	1316:1352	sustainable biomass-derived chemicals	1316:1352	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	1	50	theme	biomass	230:236	arg1	conversion					216:225	the efficient conversion	202:225	the efficient conversion of biomass to desirable chemicals	202:259	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	0	51	theme	solid	62:66	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	2	52	theme	Al	522:523	arg1	NO3					525:527	Al(NO3)3	522:529	Al(NO3)3	522:529	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	8	53	theme	catalysts	1397:1405	arg1	use					1366:1368	the use	1362:1368	the use of stable and eco-friendly catalysts	1362:1405	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	3	54	theme	N-doped	549:555	arg1	N-BC					561:564	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	2	55	theme	solid	352:356	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	0	56	theme	aluminum	53:60	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	2	57	dep	precursor	493:501	arg1	starch					504:509	starch	504:509	starch	504:509	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	57	dep	precursor	493:501	arg1	NO3					525:527	Al(NO3)3	522:529	Al(NO3)3	522:529	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	57	dep	precursor	493:501	arg1	urea					512:515	urea	512:515	urea	512:515	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	2	58	with	catalyst	363:370	arg1	sites					402:406	Brønsted-Lewis dual acid sites	377:406	Brønsted-Lewis dual acid sites	377:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	3	59	theme	BC	557:558	arg1	N-BC					561:564	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	2	60	theme	aluminum	343:350	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	4	61	theme	stable	741:746	arg1	embedding					748:756	stable embedding	741:756	stable embedding	741:756	MA treatment promoted uniform dispersion and stable embedding of Al-based components in the N-BC support with nitrogen- and oxygen-containing functional groups.					
36972830	3	62	theme	selective	620:628	arg1	conversion					640:649	the selective catalytic conversion	616:649	the selective catalytic conversion of cellulose	616:662	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	3	63	theme	Al	577:578	arg1	MA-Al/N-BC					591:600	MA-Al/N-BC	591:600	MA-Al/N-BC	591:600	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	3	63	theme	Al	577:578	arg1	composite					580:588	Al composite	577:588	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	0	64	with	Construction	0:11	arg1	sites					112:116	Brønsted-Lewis dual acid sites	87:116	Brønsted-Lewis dual acid sites for efficient conversion of cellulose	87:154	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	2	65	theme	amorphous	333:341	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	8	66	theme	promising	1275:1283	arg1	solution					1285:1292	a promising solution	1273:1292	a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts	1273:1405	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	6	67	theme	%	1121:1121	arg1	yield					1132:1136	a LA yield	1127:1136	a LA yield of 70.1 %	1127:1146	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	6	67	theme	%	1121:1121	arg1	rate					1108:1111	a cellulose conversion rate	1085:1111	a cellulose conversion rate of 93.1 %	1085:1121	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	6	68	theme	LA	1129:1130	arg1	yield					1132:1136	a LA yield	1127:1136	a LA yield of 70.1 %	1127:1146	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	2	69	theme	-supported	322:331	arg1	catalyst					363:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst	301:370	a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites	301:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	1	70	theme	desirable	241:249	arg1	chemicals					251:259	desirable chemicals	241:259	desirable chemicals	241:259	The development of sustainable catalysts for the efficient conversion of biomass to desirable chemicals is significant and challenging.					
36972830	0	71	theme	catalyst	73:80	arg1	Construction					0:11	Construction	0:11	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.	0:155	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	7	72	theme	carbohydrates	1226:1238	arg1	conversion					1206:1215	catalytic conversion	1196:1215	catalytic conversion of other carbohydrates	1196:1238	Additionally, it also showed high activity for catalytic conversion of other carbohydrates.					
36972830	8	73	theme	stable	1373:1378	arg1	catalysts					1397:1405	stable and eco-friendly catalysts	1373:1405	stable and eco-friendly catalysts	1373:1405	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	6	74	theme	optimal	1030:1036	arg1	conditions					1047:1056	optimal reaction conditions	1030:1056	optimal reaction conditions (180 °C, 4 h)	1030:1070	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	2	75	theme	Brønsted-Lewis	377:390	arg1	sites					402:406	Brønsted-Lewis dual acid sites	377:406	Brønsted-Lewis dual acid sites	377:406	Herein, a stable biochar (BC)-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites was constructed through one-step calcination of a mechanical activation (MA)-treated precursor (starch, urea, and Al(NO3)3).					
36972830	8	76	link	biomass-derived	1328:1342	arg1	chemicals					1344:1352	sustainable biomass-derived chemicals	1316:1352	sustainable biomass-derived chemicals	1316:1352	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	0	77	theme	acid	68:71	arg1	catalyst					73:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	a stable biochar-supported amorphous aluminum solid acid catalyst	16:80	Construction of a stable biochar-supported amorphous aluminum solid acid catalyst with Brønsted-Lewis dual acid sites for efficient conversion of cellulose.					
36972830	6	78	theme	conversion	1097:1106	arg1	rate					1108:1111	a cellulose conversion rate	1085:1111	a cellulose conversion rate of 93.1 %	1085:1121	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	3	79	theme	-supported	566:575	arg1	N-BC					561:564	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
36972830	6	80	theme	%	1146:1146	arg1	yield					1132:1136	a LA yield	1127:1136	a LA yield of 70.1 %	1127:1146	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	6	80	theme	%	1146:1146	arg1	rate					1108:1111	a cellulose conversion rate	1085:1111	a cellulose conversion rate of 93.1 %	1085:1121	When the MA-Al/N-BC catalyst was used under optimal reaction conditions (180 °C, 4 h), it achieved a cellulose conversion rate of 93.1 % and a LA yield of 70.1 %.					
36972830	8	81	theme	chemicals	1344:1352	arg1	production					1302:1311	the production	1298:1311	the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts	1298:1405	The results of this study offer a promising solution for the production of sustainable biomass-derived chemicals through the use of stable and eco-friendly catalysts.					
36972830	3	82	used	used	607:610	arg2	N-BC					561:564	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC)	533:601	The as-prepared N-doped BC (N-BC)-supported Al composite (MA-Al/N-BC) was used for the selective catalytic conversion of cellulose to produce levulinic acid (LA).					
35074129	8	0	theme	great	1073:1077	arg1	potential					1079:1087	great potential	1073:1087	great potential for food packaging	1073:1106	Overall, the chitosan-based films showed great potential for food packaging.					
35074129	2	1	from	improvement	405:415	arg1	mechanical					420:429	mechanical	420:429	mechanical	420:429	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	1	from	improvement	405:415	arg1	resistance					438:447	water resistance	432:447	water resistance	432:447	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	1	from	improvement	405:415	arg1	properties					475:484	antioxidant properties	463:484	antioxidant properties	463:484	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	1	from	improvement	405:415	arg1	thermal					450:456	thermal	450:456	thermal	450:456	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	2	theme	ramie	344:348	arg1	ratios					334:339	different ratios	324:339	different ratios of ramie fibre and lignin	324:365	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	6	3	theme	films	924:928	arg1	effects					903:909	the food preservation effects	881:909	the food preservation effects of composite films and PE films	881:941	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	5	4	theme	thermal	833:839	arg1	stability					841:849	the thermal stability	829:849	the thermal stability	829:849	However, due to their high pyrolysis temperatures, there was little difference between ramie fibre and lignin in improving the thermal stability.					
35074129	6	5	theme	composite	914:922	arg1	films					924:928	composite films	914:928	composite films	914:928	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	3	6	theme	tensile	549:555	arg1	strength					557:564	the tensile strength	545:564	the tensile strength	545:564	The addition of 20 wt% ramie fibre increased the tensile strength by 29.6%.					
35074129	3	7	theme	20 wt	516:520	arg1	ramie					523:527	20 wt% ramie fibre	516:533	20 wt% ramie fibre	516:533	The addition of 20 wt% ramie fibre increased the tensile strength by 29.6%.					
35074129	4	8	theme	water	679:683	arg1	absorption					685:694	the water absorption	675:694	the water absorption	675:694	Moreover, the addition of 20 wt% of lignin increased the antioxidant activity by 288%, and reduced the water absorption by 41.2%.					
35074129	0	9	theme	food	87:90	arg1	packaging					92:100	food packaging	87:100	food packaging	87:100	A biodegradable chitosan-based composite film reinforced by ramie fibre and lignin for food packaging.					
35074129	3	10	theme	%	521:521	arg1	ramie					523:527	20 wt% ramie fibre	516:533	20 wt% ramie fibre	516:533	The addition of 20 wt% ramie fibre increased the tensile strength by 29.6%.					
35074129	8	11	theme	chitosan-based	1045:1058	arg1	films					1060:1064	the chitosan-based films	1041:1064	the chitosan-based films	1041:1064	Overall, the chitosan-based films showed great potential for food packaging.					
35074129	1	12	theme	plastic	161:167	arg1	films					184:188	plastic food packaging films	161:188	plastic food packaging films	161:188	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	8	13	theme	food	1093:1096	arg1	packaging					1098:1106	food packaging	1093:1106	food packaging	1093:1106	Overall, the chitosan-based films showed great potential for food packaging.					
35074129	7	14	theme	composite	995:1003	arg1	films					1005:1009	the composite films	991:1009	the composite films	991:1009	The application evaluation results showed that the composite films were more effective.					
35074129	7	14	theme	composite	995:1003	arg1	effective					1021:1029	effective	1021:1029	effective	1021:1029	The application evaluation results showed that the composite films were more effective.					
35074129	1	15	theme	food	169:172	arg1	films					184:188	plastic food packaging films	161:188	plastic food packaging films	161:188	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	0	16	theme	biodegradable	2:14	arg1	film					41:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film reinforced by ramie fibre and lignin for food packaging.					
35074129	1	17	theme	packaging	174:182	arg1	films					184:188	plastic food packaging films	161:188	plastic food packaging films	161:188	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	5	18	theme	high	728:731	arg1	temperatures					743:754	their high pyrolysis temperatures	722:754	their high pyrolysis temperatures	722:754	However, due to their high pyrolysis temperatures, there was little difference between ramie fibre and lignin in improving the thermal stability.					
35074129	6	19	theme	preservation	890:901	arg1	effects					903:909	the food preservation effects	881:909	the food preservation effects of composite films and PE films	881:941	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	2	20	theme	lignin	360:365	arg1	ratios					334:339	different ratios	324:339	different ratios of ramie fibre and lignin	324:365	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	0	21	theme	composite	31:39	arg1	film					41:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film reinforced by ramie fibre and lignin for food packaging.					
35074129	6	22	theme	food	885:888	arg1	effects					903:909	the food preservation effects	881:909	the food preservation effects of composite films and PE films	881:941	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	3	23	theme	ramie	523:527	arg1	addition					504:511	The addition	500:511	The addition of 20 wt% ramie fibre	500:533	The addition of 20 wt% ramie fibre increased the tensile strength by 29.6%.					
35074129	2	24	theme	significant	393:403	arg1	improvement					405:415	a significant improvement	391:415	a significant improvement in mechanical, water resistance, thermal, and antioxidant properties	391:484	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	0	25	theme	chitosan-based	16:29	arg1	film					41:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film	0:44	A biodegradable chitosan-based composite film reinforced by ramie fibre and lignin for food packaging.					
35074129	6	26	theme	PE	934:935	arg1	films					937:941	PE films	934:941	PE films	934:941	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	3	27	theme	fibre	529:533	arg1	ramie					523:527	20 wt% ramie fibre	516:533	20 wt% ramie fibre	516:533	The addition of 20 wt% ramie fibre increased the tensile strength by 29.6%.					
35074129	4	28	theme	antioxidant	633:643	arg1	activity					645:652	the antioxidant activity	629:652	the antioxidant activity	629:652	Moreover, the addition of 20 wt% of lignin increased the antioxidant activity by 288%, and reduced the water absorption by 41.2%.					
35074129	1	29	theme	casting	287:293	arg1	method					295:300	the casting method	283:300	the casting method	283:300	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	1	30	dep	ramie	244:248	arg1	fibre					250:254	fibre	250:254	fibre	250:254	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	4	31	theme	lignin	612:617	arg1	lignin					612:617	lignin	612:617	lignin	612:617	Moreover, the addition of 20 wt% of lignin increased the antioxidant activity by 288%, and reduced the water absorption by 41.2%.					
35074129	4	31	theme	lignin	612:617	arg1	%					607:607	20 wt%	602:607	20 wt% of lignin	602:617	Moreover, the addition of 20 wt% of lignin increased the antioxidant activity by 288%, and reduced the water absorption by 41.2%.					
35074129	1	32	theme	biodegradable	193:205	arg1	film					222:225	a biodegradable chitosan-based film	191:225	a biodegradable chitosan-based film containing micro ramie fibre and lignin	191:265	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	2	33	theme	chitosan	374:381	arg1	matrix					383:388	the chitosan matrix	370:388	the chitosan matrix	370:388	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	5	34	theme	pyrolysis	733:741	arg1	temperatures					743:754	their high pyrolysis temperatures	722:754	their high pyrolysis temperatures	722:754	However, due to their high pyrolysis temperatures, there was little difference between ramie fibre and lignin in improving the thermal stability.					
35074129	1	35	theme	chitosan-based	207:220	arg1	film					222:225	a biodegradable chitosan-based film	191:225	a biodegradable chitosan-based film containing micro ramie fibre and lignin	191:265	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	7	36	theme	evaluation	960:969	arg1	results					971:977	The application evaluation results	944:977	The application evaluation results	944:977	The application evaluation results showed that the composite films were more effective.					
35074129	0	37	theme	fibre	66:70	arg1	ramie					60:64	ramie fibre	60:70	ramie fibre	60:70	A biodegradable chitosan-based composite film reinforced by ramie fibre and lignin for food packaging.					
35074129	1	38	contain	containing	227:236	arg1	film					222:225	a biodegradable chitosan-based film	191:225	a biodegradable chitosan-based film containing micro ramie fibre and lignin	191:265	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	1	38	contain	containing	227:236	arg2	lignin					260:265	lignin	260:265	lignin	260:265	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	1	38	contain	containing	227:236	arg2	ramie					244:248	micro ramie fibre and lignin	238:265	ramie	244:248	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	2	39	theme	ratios	334:339	arg1	addition					312:319	the addition	308:319	the addition of different ratios of ramie fibre and lignin to the chitosan matrix	308:388	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	40	theme	water	432:436	arg1	resistance					438:447	water resistance	432:447	water resistance	432:447	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	2	41	theme	different	324:332	arg1	ratios					334:339	different ratios	324:339	different ratios of ramie fibre and lignin	324:365	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	5	42	theme	fibre	799:803	arg1	ramie					793:797	ramie fibre	793:803	ramie fibre	793:803	However, due to their high pyrolysis temperatures, there was little difference between ramie fibre and lignin in improving the thermal stability.					
35074129	7	43	theme	application	948:958	arg1	results					971:977	The application evaluation results	944:977	The application evaluation results	944:977	The application evaluation results showed that the composite films were more effective.					
35074129	2	44	theme	fibre	350:354	arg1	ramie					344:348	ramie fibre	344:354	ramie fibre	344:354	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	6	45	theme	films	937:941	arg1	effects					903:909	the food preservation effects	881:909	the food preservation effects of composite films and PE films	881:941	Finally, this study compared the food preservation effects of composite films and PE films.					
35074129	5	46	theme	little	767:772	arg1	difference					774:783	little difference	767:783	little difference between ramie fibre and lignin	767:814	However, due to their high pyrolysis temperatures, there was little difference between ramie fibre and lignin in improving the thermal stability.					
35074129	1	47	theme	environmental	127:139	arg1	pollution					141:149	environmental pollution	127:149	environmental pollution	127:149	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	4	48	theme	%	607:607	arg1	addition					590:597	the addition	586:597	the addition of 20 wt% of lignin	586:617	Moreover, the addition of 20 wt% of lignin increased the antioxidant activity by 288%, and reduced the water absorption by 41.2%.					
35074129	1	49	theme	micro	238:242	arg1	ramie					244:248	micro ramie fibre and lignin	238:265	ramie	244:248	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35074129	2	50	theme	antioxidant	463:473	arg1	properties					475:484	antioxidant properties	463:484	antioxidant properties	463:484	With the addition of different ratios of ramie fibre and lignin to the chitosan matrix, a significant improvement in mechanical, water resistance, thermal, and antioxidant properties was observed.					
35074129	1	51	theme	pollution	141:149	arg1	problem					116:122	the problem	112:122	the problem of environmental pollution caused by plastic food packaging films	112:188	To solve the problem of environmental pollution caused by plastic food packaging films, a biodegradable chitosan-based film containing micro ramie fibre and lignin was prepared by the casting method.					
35676546	4	0	theme	photoelectric	640:652	arg1	material					654:661	The photoelectric material	636:661	The photoelectric material	636:661	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	9	1	theme	thiamethoxam	1549:1560	arg1	determination					1526:1538	the determination	1522:1538	the determination of trace thiamethoxam in environmental water and soil leaching solutions	1522:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	2	2	theme	tin	369:371	arg1	electrode					385:393	the fluorine-doped tin oxide (FTO) electrode	350:393	the fluorine-doped tin oxide (FTO) electrode	350:393	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	9	3	theme	environmental	1565:1577	arg1	water					1579:1583	environmental water	1565:1583	environmental water	1565:1583	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	2	4	theme	in	435:436	arg1	exchange					447:454	in situ ion exchange	435:454	in situ ion exchange	435:454	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	10	5	theme	imprinted	1680:1688	arg1	sensor					1720:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor	1660:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX)	1660:1807	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	4	6	theme	dispersive	744:753	arg1	spectroscopy					761:772	energy dispersive x-ray spectroscopy	737:772	energy dispersive x-ray spectroscopy	737:772	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	9	7	theme	leaching	1594:1601	arg1	solutions					1603:1611	soil leaching solutions	1589:1611	soil leaching solutions	1589:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	6	8	theme	electron	1069:1076	arg1	transfer					1078:1085	the electron transfer	1065:1085	the electron transfer	1065:1085	When thiamethoxam was re-adsorbed on the imprinted membrane, the current recorded at 0 V (vs. Ag/AgCl) was reduced because the thiamethoxam molecule blocked the electron transfer.					
35676546	4	9	theme	scanning	703:710	arg1	microscopy					721:730	scanning electron microscopy	703:730	scanning electron microscopy	703:730	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	5	10	theme	electron	788:795	arg1	mechanism					806:814	The electron transfer mechanism	784:814	The electron transfer mechanism of Z-type heterojunction	784:839	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	3	11	theme	template	617:624	arg1	chitosan					514:521	chitosan	514:521	chitosan	514:521	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	3	11	theme	template	617:624	arg1	molecule					626:633	the template molecule	613:633	the template molecule	613:633	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	2	12	theme	heterojunction	298:311	arg1	material					327:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	8	13	theme	Most	1356:1359	arg1	pesticides					1361:1370	Most pesticides	1356:1370	Most pesticides	1356:1370	Most pesticides, such as propoxur and isoprocarband carbaryl, do not interfere with the determination.					
35676546	8	13	theme	Most	1356:1359	arg1	isoprocarband					1394:1406	isoprocarband	1394:1406	isoprocarband	1394:1406	Most pesticides, such as propoxur and isoprocarband carbaryl, do not interfere with the determination.					
35676546	8	13	theme	Most	1356:1359	arg1	propoxur					1381:1388	propoxur	1381:1388	propoxur	1381:1388	Most pesticides, such as propoxur and isoprocarband carbaryl, do not interfere with the determination.					
35676546	6	14	theme	thiamethoxam	1035:1046	arg1	molecule					1048:1055	the thiamethoxam molecule	1031:1055	the thiamethoxam molecule	1031:1055	When thiamethoxam was re-adsorbed on the imprinted membrane, the current recorded at 0 V (vs. Ag/AgCl) was reduced because the thiamethoxam molecule blocked the electron transfer.					
35676546	4	15	dep	diffraction	690:700	arg1	analyses					774:781	analyses	774:781	analyses	774:781	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	9	16	theme	%	1643:1643	arg1	recovery					1621:1628	a recovery	1619:1628	a recovery of 99.6-102.1% (RSD < 3.74%)	1619:1657	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	13	17	theme	sensitive	2078:2086	arg1	response					2088:2095	an extremely sensitive response	2065:2095	an extremely sensitive response to thiamethoxam	2065:2111	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	0	18	theme	thiamethoxam	97:108	arg1	determination					110:122	thiamethoxam determination	97:122	thiamethoxam determination	97:122	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	11	19	theme	first	1911:1915	arg1	time					1917:1920	the first time	1907:1920	the first time	1907:1920	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material was synthesized for the first time.					
35676546	5	20	theme	Z-type	819:824	arg1	heterojunction					826:839	Z-type heterojunction	819:839	Z-type heterojunction	819:839	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	13	21	theme	ZnO/Bi2O3/Bi2S3	2214:2228	arg1	properties					2200:2209	the excellent photoelectrochemical properties	2165:2209	the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2165:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	1	22	theme	high	182:185	arg1	sensitivity					187:197	high sensitivity	182:197	high sensitivity	182:197	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	2	23	theme	ion	443:445	arg1	exchange					447:454	in situ ion exchange	435:454	in situ ion exchange	435:454	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	8	24	dep	propoxur	1381:1388	arg1	carbaryl					1408:1415	carbaryl	1408:1415	carbaryl	1408:1415	Most pesticides, such as propoxur and isoprocarband carbaryl, do not interfere with the determination.					
35676546	3	25	theme	polymer	478:484	arg1	membrane					486:493	A chitosan-imprinted polymer membrane	457:493	A chitosan-imprinted polymer membrane	457:493	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	1	26	with	sensor	170:175	arg1	sensitivity					187:197	high sensitivity	182:197	high sensitivity	182:197	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	1	26	with	sensor	170:175	arg1	structure					210:218	stable structure	203:218	stable structure	203:218	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	0	27	theme	imprinted	27:35	arg1	sensor					51:56	molecularly imprinted photoelectric sensor	15:56	molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination	15:122	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	1	28	theme	imprinted	139:147	arg1	sensor					170:175	A molecularly imprinted photoelectrochemical sensor	125:175	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure	125:218	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	7	29	from	mol/L	1234:1238	arg1	range					1190:1194	the range	1186:1194	the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L	1186:1238	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	11	30	theme	Z-type	1826:1831	arg1	material					1878:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material was synthesized for the first time.					
35676546	5	31	theme	Mott-Schottky	887:899	arg1	curve					901:905	Mott-Schottky curve	887:905	Mott-Schottky curve	887:905	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	9	32	theme	good	1482:1485	arg1	practicability					1487:1500	good practicability	1482:1500	good practicability	1482:1500	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	9	33	from	thiamethoxam	1549:1560	arg1	water					1579:1583	environmental water	1565:1583	environmental water	1565:1583	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	9	33	from	thiamethoxam	1549:1560	arg1	solutions					1603:1611	soil leaching solutions	1589:1611	soil leaching solutions	1589:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	10	34	with	sensor	1720:1725	arg1	selectivity					1753:1763	selectivity	1753:1763	selectivity	1753:1763	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	10	34	with	sensor	1720:1725	arg1	sensitivity					1737:1747	high sensitivity	1732:1747	high sensitivity	1732:1747	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	13	35	theme	photoelectrochemical	2179:2198	arg1	properties					2200:2209	the excellent photoelectrochemical properties	2165:2209	the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2165:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	0	36	theme	ZnO/Bi2O3/Bi2S3	63:77	arg1	layer					87:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	12	37	theme	sensitive	1982:1990	arg1	material					1992:1999	the sensitive material	1978:1999	the sensitive material	1978:1999	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	12	37	theme	sensitive	1982:1990	arg1	membrane					2008:2015	membrane	2008:2015	membrane	2008:2015	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	12	37	theme	sensitive	1982:1990	arg1	sensor					1934:1939	The MI-PEC sensor	1923:1939	The MI-PEC sensor	1923:1939	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	9	38	from	solutions	1603:1611	arg1	determination					1526:1538	the determination	1522:1538	the determination of trace thiamethoxam in environmental water and soil leaching solutions	1522:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	2	39	dep	in	435:436	arg1	situ					438:441	situ	438:441	situ	438:441	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	2	40	theme	seed	398:401	arg1	growth					409:414	seed layer growth	398:414	seed layer growth	398:414	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	11	41	theme	ZnO/Bi2O3/Bi2S3	1848:1862	arg1	material					1878:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material was synthesized for the first time.					
35676546	13	42	theme	due	2158:2160	arg1	3.32 × 10-13 mol/L					2139:2156	3.32 × 10-13 mol/L	2139:2156	3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2139:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	3	43	theme	cross-linking	572:584	arg1	agent					586:590	the cross-linking agent	568:590	the cross-linking agent	568:590	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	9	44	from	water	1579:1583	arg1	determination					1526:1538	the determination	1522:1538	the determination of trace thiamethoxam in environmental water and soil leaching solutions	1522:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	4	45	theme	X-ray	684:688	arg1	diffraction					690:700	X-ray diffraction	684:700	X-ray diffraction	684:700	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	7	46	theme	detection	1337:1345	arg1	methods					1347:1353	other detection methods	1331:1353	other detection methods	1331:1353	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	7	47	theme	detection	1248:1256	arg1	3.32 × 10-13 mol/L					1268:1285	3.32 × 10-13 mol/L	1268:1285	3.32 × 10-13 mol/L	1268:1285	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	7	47	theme	detection	1248:1256	arg1	limit					1258:1262	the detection limit	1244:1262	the detection limit	1244:1262	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	0	48	with	sensor	51:56	arg1	layer					87:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	2	49	theme	drip	417:420	arg1	coating					422:428	drip coating	417:428	drip coating	417:428	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	9	50	theme	trace	1543:1547	arg1	thiamethoxam					1549:1560	trace thiamethoxam	1543:1560	trace thiamethoxam in environmental water and soil leaching solutions	1543:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	10	51	theme	MI-PEC	1712:1717	arg1	sensor					1720:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor	1660:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX)	1660:1807	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	13	52	theme	detection	2120:2128	arg1	limit					2130:2134	a detection limit	2118:2134	a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2118:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	2	53	theme	oxide	373:377	arg1	electrode					385:393	the fluorine-doped tin oxide (FTO) electrode	350:393	the fluorine-doped tin oxide (FTO) electrode	350:393	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	10	54	theme	photoelectrochemical	1690:1709	arg1	sensor					1720:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor	1660:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX)	1660:1807	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	2	55	theme	fluorine-doped	354:367	arg1	electrode					385:393	the fluorine-doped tin oxide (FTO) electrode	350:393	the fluorine-doped tin oxide (FTO) electrode	350:393	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	10	56	theme	high	1732:1735	arg1	sensitivity					1737:1747	high sensitivity	1732:1747	high sensitivity	1732:1747	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	9	57	theme	soil	1589:1592	arg1	solutions					1603:1611	soil leaching solutions	1589:1611	soil leaching solutions	1589:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	4	58	theme	energy	737:742	arg1	spectroscopy					761:772	energy dispersive x-ray spectroscopy	737:772	energy dispersive x-ray spectroscopy	737:772	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	2	59	theme	FTO	380:382	arg1	electrode					385:393	the fluorine-doped tin oxide (FTO) electrode	350:393	the fluorine-doped tin oxide (FTO) electrode	350:393	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	5	60	theme	transfer	797:804	arg1	mechanism					806:814	The electron transfer mechanism	784:814	The electron transfer mechanism of Z-type heterojunction	784:839	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	2	61	theme	photoelectric	313:325	arg1	material					327:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	1	62	theme	thiamethoxam	258:269	arg1	pesticide					271:279	thiamethoxam pesticide	258:279	thiamethoxam pesticide	258:279	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	4	63	theme	electron	712:719	arg1	microscopy					721:730	scanning electron microscopy	703:730	scanning electron microscopy	703:730	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	7	64	dep	7.0 × 10-10	1222:1232	arg1	to					1219:1220	to	1219:1220	to	1219:1220	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	7	65	theme	thiamethoxam	1156:1167	arg1	concentration					1169:1181	thiamethoxam concentration	1156:1181	thiamethoxam concentration	1156:1181	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	2	66	theme	ZnO/Bi2O3/Bi2S3	282:296	arg1	material					327:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material	282:334	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	7	67	theme	linear	1133:1138	arg1	relationship					1140:1151	a linear relationship	1131:1151	a linear relationship to thiamethoxam concentration	1131:1181	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	1	68	theme	photoelectrochemical	149:168	arg1	sensor					170:175	A molecularly imprinted photoelectrochemical sensor	125:175	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure	125:218	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	3	69	theme	functional	530:539	arg1	chitosan					514:521	chitosan	514:521	chitosan	514:521	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	3	69	theme	functional	530:539	arg1	monomer					541:547	the functional monomer	526:547	the functional monomer	526:547	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	7	70	theme	imprinted	1104:1112	arg1	sensor					1114:1119	The molecularly imprinted sensor	1088:1119	The molecularly imprinted sensor	1088:1119	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	4	71	theme	x-ray	755:759	arg1	spectroscopy					761:772	energy dispersive x-ray spectroscopy	737:772	energy dispersive x-ray spectroscopy	737:772	The photoelectric material was characterized by X-ray diffraction, scanning electron microscopy, and energy dispersive x-ray spectroscopy analyses.					
35676546	7	72	theme	other	1331:1335	arg1	methods					1347:1353	other detection methods	1331:1353	other detection methods	1331:1353	The molecularly imprinted sensor exhibited a linear relationship to thiamethoxam concentration in the range from 7.0 × 10-13 mol/L to 7.0 × 10-10 mol/L and the detection limit was 3.32 × 10-13 mol/L, which is lower than the values reported by other detection methods.					
35676546	5	73	theme	ultraviolet-visible	857:875	arg1	curve					877:881	ultraviolet-visible curve	857:881	ultraviolet-visible curve	857:881	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	1	74	theme	stable	203:208	arg1	structure					210:218	stable structure	203:218	stable structure	203:218	A molecularly imprinted photoelectrochemical sensor with high sensitivity and stable structure was constructed and applied to detect thiamethoxam pesticide.					
35676546	10	75	theme	thiamethoxam	1790:1801	arg1	determination					1773:1785	the determination	1769:1785	the determination of thiamethoxam (TMX)	1769:1807	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
35676546	5	76	theme	heterojunction	826:839	arg1	mechanism					806:814	The electron transfer mechanism	784:814	The electron transfer mechanism of Z-type heterojunction	784:839	The electron transfer mechanism of Z-type heterojunction was verified by ultraviolet-visible curve and Mott-Schottky curve.					
35676546	0	77	theme	photoelectric	37:49	arg1	sensor					51:56	molecularly imprinted photoelectric sensor	15:56	molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination	15:122	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	12	78	theme	recognition	2024:2034	arg1	element					2036:2042	the recognition element	2020:2042	the recognition element	2020:2042	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	12	78	theme	recognition	2024:2034	arg1	membrane					2008:2015	membrane	2008:2015	membrane	2008:2015	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	3	79	theme	chitosan-imprinted	459:476	arg1	membrane					486:493	A chitosan-imprinted polymer membrane	457:493	A chitosan-imprinted polymer membrane	457:493	A chitosan-imprinted polymer membrane was prepared using chitosan as the functional monomer, glutaraldehyde as the cross-linking agent, and thiamethoxam as the template molecule.					
35676546	13	80	theme	excellent	2169:2177	arg1	properties					2200:2209	the excellent photoelectrochemical properties	2165:2209	the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2165:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	0	81	theme	sensing	79:85	arg1	layer					87:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	ZnO/Bi2O3/Bi2S3 sensing layer	63:91	Chitosan-based molecularly imprinted photoelectric sensor with ZnO/Bi2O3/Bi2S3 sensing layer for thiamethoxam determination.					
35676546	9	82	from	determination	1526:1538	arg1	water					1579:1583	environmental water	1565:1583	environmental water	1565:1583	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	9	82	from	determination	1526:1538	arg1	solutions					1603:1611	soil leaching solutions	1589:1611	soil leaching solutions	1589:1611	The sensor also showed good practicability and suitability for the determination of trace thiamethoxam in environmental water and soil leaching solutions, with a recovery of 99.6-102.1% (RSD < 3.74%).					
35676546	11	83	theme	photoelectric	1864:1876	arg1	material					1878:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material was synthesized for the first time.					
35676546	2	84	theme	layer	403:407	arg1	growth					409:414	seed layer growth	398:414	seed layer growth	398:414	ZnO/Bi2O3/Bi2S3 heterojunction photoelectric material was formed on the fluorine-doped tin oxide (FTO) electrode by seed layer growth, drip coating, and in situ ion exchange.					
35676546	6	85	theme	imprinted	949:957	arg1	membrane					959:966	the imprinted membrane	945:966	the imprinted membrane	945:966	When thiamethoxam was re-adsorbed on the imprinted membrane, the current recorded at 0 V (vs. Ag/AgCl) was reduced because the thiamethoxam molecule blocked the electron transfer.					
35676546	11	86	theme	heterojunction	1833:1846	arg1	material					1878:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material	1824:1885	A Z-type heterojunction ZnO/Bi2O3/Bi2S3 photoelectric material was synthesized for the first time.					
35676546	13	87	theme	3.32 × 10-13 mol/L	2139:2156	arg1	limit					2130:2134	a detection limit	2118:2134	a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3	2118:2228	The sensor exhibits an extremely sensitive response to thiamethoxam with a detection limit of 3.32 × 10-13 mol/L due to the excellent photoelectrochemical properties of ZnO/Bi2O3/Bi2S3.					
35676546	12	88	theme	MI-PEC	1927:1932	arg1	sensor					1934:1939	The MI-PEC sensor	1923:1939	The MI-PEC sensor	1923:1939	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	12	88	theme	MI-PEC	1927:1932	arg1	membrane					2008:2015	membrane	2008:2015	membrane	2008:2015	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	12	88	theme	MI-PEC	1927:1932	arg1	material					1992:1999	the sensitive material	1978:1999	the sensitive material	1978:1999	The MI-PEC sensor was prepared with ZnO/Bi2O3/Bi2S3 as the sensitive material and MI membrane as the recognition element.					
35676546	10	89	theme	novel	1662:1666	arg1	sensor					1720:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor	1660:1725	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX)	1660:1807	A novel molecularly imprinted photoelectrochemical (MI-PEC) sensor with high sensitivity and selectivity for the determination of thiamethoxam (TMX) was developed.					
37030170	3	0	theme	material	739:746	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	0	theme	material	739:746	arg1	μf					787:788	myofiber stiffness μf	768:788	myofiber stiffness μf	768:788	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	0	theme	material	739:746	arg1	MRMPs					760:764	MRMPs	760:764	MRMPs	760:764	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	0	theme	material	739:746	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	0	theme	material	739:746	arg1	μm					805:806	ECM stiffness μm	791:806	ECM stiffness μm	791:806	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	1	1	theme	muscle	265:270	arg1	mechanics					272:280	intact muscle mechanics	258:280	intact muscle mechanics	258:280	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	7	2	theme	printing	1513:1520	arg1	protocol					1522:1529	an alginate-based hydrogel printing protocol	1486:1529	an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature	1486:1651	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	3	3	theme	myofiber	768:775	arg1	μf					787:788	myofiber stiffness μf	768:788	myofiber stiffness μf	768:788	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	3	theme	myofiber	768:775	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	4	theme	undeformed	567:576	arg1	muscle					578:583	the undeformed muscle	563:583	the undeformed muscle using the acoustoelastic theory	563:615	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	7	5	theme	alginate-based	1489:1502	arg1	protocol					1522:1529	an alginate-based hydrogel printing protocol	1486:1529	an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature	1486:1651	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	6	6	theme	FE	1205:1206	arg1	simulations					1208:1218	the FE simulations	1201:1218	the FE simulations where shear wave propagations in the corresponding composite media were simulated	1201:1300	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	6	7	used	used	1193:1196	arg2	combinations					1131:1142	Three combinations	1125:1142	Three combinations of different physiologically relevant MRMPs	1125:1186	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	1	8	theme	properties	185:194	arg1	assessment					162:171	Direct and nondestructive assessment	136:171	Direct and nondestructive assessment of material properties of skeletal muscle in vivo	136:221	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	3	9	theme	ECM	791:793	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	9	theme	ECM	791:793	arg1	μm					805:806	ECM stiffness μm	791:806	ECM stiffness μm	791:806	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	10	theme	acoustoelastic	595:608	arg1	theory					610:615	the acoustoelastic theory	591:615	the acoustoelastic theory	591:615	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	1	11	theme	skeletal	199:206	arg1	muscle					208:213	skeletal muscle	199:213	skeletal muscle	199:213	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	5	12	attach	presented	966:974	arg2	we					963:964	we	963:964	we	963:964	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	5	12	attach	presented	966:974	arg1	study					956:960	this study	951:960	this study	951:960	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	4	13	theme	MRMPs	941:945	arg1	values					931:936	ground truth values	918:936	ground truth values of MRMPs	918:945	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	9	14	theme	proposed	1832:1839	arg1	model					1853:1857	our proposed theoretical model	1828:1857	our proposed theoretical model along with ultrasound SWE	1828:1883	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	5	15	theme	3D-printed	1081:1090	arg1	phantoms					1101:1108	3D-printed hydrogel phantoms	1081:1108	3D-printed hydrogel phantoms	1081:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	7	16	dep	muscle	1385:1390	arg1	Vf=0.675,0.832					1428:1441	Vf=0.675,0.832	1428:1441	Vf=0.675,0.832	1428:1441	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	7	16	dep	muscle	1385:1390	arg1	μf=2.02kPa					1399:1408	μf=2.02kPa	1399:1408	μf=2.02kPa	1399:1408	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	7	16	dep	muscle	1385:1390	arg1	μm=52.42kPa					1411:1421	μm=52.42kPa	1411:1421	μm=52.42kPa	1411:1421	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	9	17	theme	model	1853:1857	arg1	potential					1815:1823	the potential	1811:1823	the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way	1811:1987	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	4	18	theme	ground	918:923	arg1	values					931:936	ground truth values	918:936	ground truth values of MRMPs	918:945	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	3	19	dep	parameters	748:757	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	19	dep	parameters	748:757	arg1	μf					787:788	myofiber stiffness μf	768:788	myofiber stiffness μf	768:788	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	19	dep	parameters	748:757	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	19	dep	parameters	748:757	arg1	μm					805:806	ECM stiffness μm	791:806	ECM stiffness μm	791:806	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	6	20	theme	corresponding	1257:1269	arg1	media					1281:1285	the corresponding composite media	1253:1285	the corresponding composite media	1253:1285	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	8	21	dep	estimates	1691:1699	arg1	μm					1684:1685	μm	1684:1685	μm	1684:1685	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	21	dep	estimates	1691:1699	arg1	μf					1681:1682	μf	1681:1682	μf	1681:1682	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	21	dep	estimates	1691:1699	arg1	Vf					1687:1688	Vf	1687:1688	Vf	1687:1688	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	5	22	theme	FE	1061:1062	arg1	simulations					1065:1075	finite-element (FE) simulations	1045:1075	finite-element (FE) simulations	1045:1075	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	4	23	theme	values	931:936	arg1	lack					910:913	the lack	906:913	the lack of ground truth values of MRMPs	906:945	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	3	24	theme	shear	671:675	arg1	SWE					696:698	SWE	696:698	SWE	696:698	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	24	theme	shear	671:675	arg1	elastography					682:693	ultrasound-based shear wave elastography	654:693	ultrasound-based shear wave elastography (SWE)	654:699	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	1	25	theme	Direct	136:141	arg1	assessment					162:171	Direct and nondestructive assessment	136:171	Direct and nondestructive assessment of material properties of skeletal muscle in vivo	136:221	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	7	26	theme	skeletal	1376:1383	arg1	muscle					1385:1390	a real skeletal muscle	1369:1390	a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging	1369:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	3	27	theme	volume	822:827	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	27	theme	volume	822:827	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	0	28	theme	skeletal	86:93	arg1	muscle					95:100	skeletal muscle	86:100	skeletal muscle	86:100	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	1	29	theme	nondestructive	147:160	arg1	assessment					162:171	Direct and nondestructive assessment	136:171	Direct and nondestructive assessment of material properties of skeletal muscle in vivo	136:221	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	7	30	theme	hydrogels	1614:1622	arg1	embedding					1591:1599	the freeform reversible embedding	1567:1599	the freeform reversible embedding of suspended hydrogels (FRESH)	1567:1630	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	6	31	from	propagations	1237:1248	arg1	media					1281:1285	the corresponding composite media	1253:1285	the corresponding composite media	1253:1285	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	0	32	theme	in	106:107	arg1	study					129:133	an in silico and in vitro study	103:133	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	5	33	theme	analytical	976:985	arg1	validations					1004:1014	analytical and experimental validations	976:1014	analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms	976:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	9	34	theme	muscle	1948:1953	arg1	characteristics					1916:1930	microstructural characteristics	1900:1930	microstructural characteristics of the skeletal muscle	1900:1953	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	0	35	dep	in	106:107	arg1	silico					109:114	silico	109:114	silico	109:114	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	7	36	theme	real	1371:1374	arg1	muscle					1385:1390	a real skeletal muscle	1369:1390	a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging	1369:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	0	37	theme	Nondestructive	0:13	arg1	evaluation					26:35	Nondestructive ultrasound evaluation	0:35	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	6	38	theme	wave	1232:1235	arg1	propagations					1237:1248	shear wave propagations	1226:1248	shear wave propagations in the corresponding composite media	1226:1285	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	9	39	theme	nondestructive	1970:1983	arg1	way					1985:1987	an entirely nondestructive way	1958:1987	an entirely nondestructive way	1958:1987	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	7	40	theme	freeform	1571:1578	arg1	embedding					1591:1599	the freeform reversible embedding	1567:1599	the freeform reversible embedding of suspended hydrogels (FRESH)	1567:1630	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	4	41	theme	proposed	843:850	arg1	method					852:857	The proposed method	839:857	The proposed method	839:857	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	0	42	theme	microstructure-related	40:61	arg1	parameters					72:81	microstructure-related material parameters	40:81	microstructure-related material parameters of skeletal muscle	40:100	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	2	43	theme	hierarchical	366:377	arg1	microstructure					379:392	intricate hierarchical microstructure	356:392	intricate hierarchical microstructure of the skeletal muscle	356:415	However, this is challenged by intricate hierarchical microstructure of the skeletal muscle.					
37030170	0	44	theme	parameters	72:81	arg1	evaluation					26:35	Nondestructive ultrasound evaluation	0:35	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	3	45	theme	microstructure-related	716:737	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	45	theme	microstructure-related	716:737	arg1	μf					787:788	myofiber stiffness μf	768:788	myofiber stiffness μf	768:788	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	45	theme	microstructure-related	716:737	arg1	MRMPs					760:764	MRMPs	760:764	MRMPs	760:764	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	45	theme	microstructure-related	716:737	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	45	theme	microstructure-related	716:737	arg1	μm					805:806	ECM stiffness μm	791:806	ECM stiffness μm	791:806	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	6	46	dep	different	1147:1155	arg1	relevant					1173:1180	relevant	1173:1180	relevant	1173:1180	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	7	47	from	method	1632:1637	arg1	literature					1642:1651	literature	1642:1651	literature	1642:1651	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	0	48	dep	evaluation	26:35	arg1	study					129:133	an in silico and in vitro study	103:133	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	7	49	theme	hydrogel	1318:1325	arg1	phantoms					1327:1334	Two 3D-printed hydrogel phantoms	1303:1334	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging	1303:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	8	50	dep	in	1734:1735	arg1	%					1722:1722	2.7%	1719:1722	2.7%	1719:1722	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	50	dep	in	1734:1735	arg1	%					1727:1727	7.3%	1724:1727	7.3%	1724:1727	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	50	dep	in	1734:1735	arg1	%					1732:1732	2.4%	1729:1732	2.4%	1729:1732	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	50	dep	in	1734:1735	arg1	silico					1737:1742	silico	1737:1742	silico	1737:1742	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	3	51	theme	shear	537:541	arg1	propagation					548:558	shear wave propagation	537:558	shear wave propagation	537:558	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	7	52	dep	μf=2.02kPa	1399:1408	arg1	i.e.					1393:1396	i.e.	1393:1396	i.e.	1393:1396	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	5	53	theme	proposed	1023:1030	arg1	method					1032:1037	the proposed method	1019:1037	the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms	1019:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	1	54	theme	intact	258:263	arg1	mechanics					272:280	intact muscle mechanics	258:280	intact muscle mechanics	258:280	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	7	55	theme	hydrogel	1504:1511	arg1	protocol					1522:1529	an alginate-based hydrogel printing protocol	1486:1529	an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature	1486:1651	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	9	56	theme	quantitative	1779:1790	arg1	study					1792:1796	This quantitative study	1774:1796	This quantitative study	1774:1796	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	8	57	theme	percent	1662:1668	arg1	errors					1670:1675	Average percent errors	1654:1675	Average percent errors of (μf,μm,Vf) estimates	1654:1699	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	58	theme	estimates	1691:1699	arg1	errors					1670:1675	Average percent errors	1654:1675	Average percent errors of (μf,μm,Vf) estimates	1654:1699	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	1	59	theme	mechanics	272:280	arg1	understanding					241:253	our understanding	237:253	our understanding of intact muscle mechanics	237:280	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	3	60	theme	stiffness	777:785	arg1	μf					787:788	myofiber stiffness μf	768:788	myofiber stiffness μf	768:788	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	60	theme	stiffness	777:785	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	1	61	theme	material	176:183	arg1	properties					185:194	material properties	176:194	material properties of skeletal muscle	176:213	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	4	62	theme	further	868:874	arg1	validation					876:885	further validation	868:885	further validation	868:885	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	7	63	theme	ultrasound	1448:1457	arg1	imaging					1459:1465	ultrasound imaging	1448:1465	ultrasound imaging	1448:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	7	64	with	phantoms	1327:1334	arg1	MRMPs					1345:1349	the MRMPs	1341:1349	the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging	1341:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	3	65	theme	stiffness	795:803	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	65	theme	stiffness	795:803	arg1	μm					805:806	ECM stiffness μm	791:806	ECM stiffness μm	791:806	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	1	66	theme	muscle	208:213	arg1	properties					185:194	material properties	176:194	material properties of skeletal muscle	176:213	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	2	67	theme	skeletal	401:408	arg1	muscle					410:415	the skeletal muscle	397:415	the skeletal muscle	397:415	However, this is challenged by intricate hierarchical microstructure of the skeletal muscle.					
37030170	6	68	theme	MRMPs	1182:1186	arg1	combinations					1131:1142	Three combinations	1125:1142	Three combinations of different physiologically relevant MRMPs	1125:1186	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	9	69	theme	theoretical	1841:1851	arg1	model					1853:1857	our proposed theoretical model	1828:1857	our proposed theoretical model along with ultrasound SWE	1828:1883	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	5	70	theme	hydrogel	1092:1099	arg1	phantoms					1101:1108	3D-printed hydrogel phantoms	1081:1108	3D-printed hydrogel phantoms	1081:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	6	71	theme	composite	1271:1279	arg1	media					1281:1285	the corresponding composite media	1253:1285	the corresponding composite media	1253:1285	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	3	72	theme	myofiber	813:820	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	72	theme	myofiber	813:820	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	73	theme	ultrasound-based	654:669	arg1	SWE					696:698	SWE	696:698	SWE	696:698	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	73	theme	ultrasound-based	654:669	arg1	elastography					682:693	ultrasound-based shear wave elastography	654:693	ultrasound-based shear wave elastography (SWE)	654:699	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	4	74	theme	truth	925:929	arg1	values					931:936	ground truth values	918:936	ground truth values of MRMPs	918:945	The proposed method warrants further validation but is hampered by the lack of ground truth values of MRMPs.					
37030170	7	75	theme	3D-printed	1307:1316	arg1	phantoms					1327:1334	Two 3D-printed hydrogel phantoms	1303:1334	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging	1303:1465	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	0	76	theme	muscle	95:100	arg1	parameters					72:81	microstructure-related material parameters	40:81	microstructure-related material parameters of skeletal muscle	40:100	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	7	77	dep	hydrogels	1614:1622	arg1	FRESH					1625:1629	FRESH	1625:1629	FRESH	1625:1629	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	6	78	theme	shear	1226:1230	arg1	propagations					1237:1248	shear wave propagations	1226:1248	shear wave propagations in the corresponding composite media	1226:1285	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	9	79	theme	microstructural	1900:1914	arg1	characteristics					1916:1930	microstructural characteristics	1900:1930	microstructural characteristics of the skeletal muscle	1900:1953	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	3	80	theme	ratio	829:833	arg1	Vf					835:836	myofiber volume ratio Vf	813:836	myofiber volume ratio Vf	813:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	80	theme	ratio	829:833	arg1	parameters					748:757	microstructure-related material parameters	716:757	microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf	716:836	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	7	81	theme	suspended	1604:1612	arg1	hydrogels					1614:1622	suspended hydrogels	1604:1622	suspended hydrogels (FRESH)	1604:1630	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	0	82	dep	in	120:121	arg1	vitro					123:127	vitro	123:127	vitro	123:127	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	8	83	dep	in	1764:1765	arg1	%					1752:1752	3.0%	1749:1752	3.0%	1749:1752	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	83	dep	in	1764:1765	arg1	%					1757:1757	8.0%	1754:1757	8.0%	1754:1757	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	83	dep	in	1764:1765	arg1	%					1762:1762	9.9%	1759:1762	9.9%	1759:1762	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	8	83	dep	in	1764:1765	arg1	vitro					1767:1771	vitro	1767:1771	vitro	1767:1771	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	9	84	theme	skeletal	1939:1946	arg1	muscle					1948:1953	the skeletal muscle	1935:1953	the skeletal muscle	1935:1953	This quantitative study corroborated the potential of our proposed theoretical model along with ultrasound SWE for uncovering microstructural characteristics of the skeletal muscle in an entirely nondestructive way.					
37030170	0	85	theme	in	120:121	arg1	study					129:133	an in silico and in vitro study	103:133	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	0	86	theme	ultrasound	15:24	arg1	evaluation					26:35	Nondestructive ultrasound evaluation	0:35	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.	0:134	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	2	87	theme	muscle	410:415	arg1	microstructure					379:392	intricate hierarchical microstructure	356:392	intricate hierarchical microstructure of the skeletal muscle	356:415	However, this is challenged by intricate hierarchical microstructure of the skeletal muscle.					
37030170	1	88	theme	personalized	297:308	arg1	interventions					310:322	personalized interventions	297:322	personalized interventions	297:322	Direct and nondestructive assessment of material properties of skeletal muscle in vivo shall advance our understanding of intact muscle mechanics and facilitate personalized interventions.					
37030170	3	89	theme	extracellular	498:510	arg1	ECM					520:522	ECM	520:522	ECM	520:522	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	89	theme	extracellular	498:510	arg1	matrix					512:517	extracellular matrix	498:517	extracellular matrix (ECM)	498:523	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	0	90	theme	material	63:70	arg1	parameters					72:81	microstructure-related material parameters	40:81	microstructure-related material parameters of skeletal muscle	40:100	Nondestructive ultrasound evaluation of microstructure-related material parameters of skeletal muscle: an in silico and in vitro study.					
37030170	7	91	theme	reversible	1580:1589	arg1	embedding					1591:1599	the freeform reversible embedding	1567:1599	the freeform reversible embedding of suspended hydrogels (FRESH)	1567:1630	Two 3D-printed hydrogel phantoms with the MRMPs close to those of a real skeletal muscle (i.e., μf=2.02kPa, μm=52.42kPa, and Vf=0.675,0.832) for ultrasound imaging were fabricated by an alginate-based hydrogel printing protocol that we modified and optimized from the freeform reversible embedding of suspended hydrogels (FRESH) method in literature.					
37030170	5	92	theme	method	1032:1037	arg1	validations					1004:1014	analytical and experimental validations	976:1014	analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms	976:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	3	93	theme	skeletal	450:457	arg1	myofibers					484:492	myofibers	484:492	myofibers	484:492	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	93	theme	skeletal	450:457	arg1	muscle					459:464	the skeletal muscle	446:464	the skeletal muscle	446:464	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	93	theme	skeletal	450:457	arg1	composite					471:479	a composite	469:479	a composite of myofibers	469:492	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	94	theme	wave	677:680	arg1	SWE					696:698	SWE	696:698	SWE	696:698	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	94	theme	wave	677:680	arg1	elastography					682:693	ultrasound-based shear wave elastography	654:693	ultrasound-based shear wave elastography (SWE)	654:699	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	95	theme	myofibers	484:492	arg1	ECM					520:522	ECM	520:522	ECM	520:522	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	95	theme	myofibers	484:492	arg1	myofibers					484:492	myofibers	484:492	myofibers	484:492	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	95	theme	myofibers	484:492	arg1	matrix					512:517	extracellular matrix	498:517	extracellular matrix (ECM)	498:523	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	95	theme	myofibers	484:492	arg1	composite					471:479	a composite	469:479	a composite of myofibers	469:492	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	3	95	theme	myofibers	484:492	arg1	muscle					459:464	the skeletal muscle	446:464	the skeletal muscle	446:464	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
37030170	5	96	theme	finite-element	1045:1058	arg1	simulations					1065:1075	finite-element (FE) simulations	1045:1075	finite-element (FE) simulations	1045:1075	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	2	97	theme	intricate	356:364	arg1	microstructure					379:392	intricate hierarchical microstructure	356:392	intricate hierarchical microstructure of the skeletal muscle	356:415	However, this is challenged by intricate hierarchical microstructure of the skeletal muscle.					
37030170	6	98	theme	different	1147:1155	arg1	MRMPs					1182:1186	different physiologically relevant MRMPs	1147:1186	different physiologically relevant MRMPs	1147:1186	Three combinations of different physiologically relevant MRMPs were used in the FE simulations where shear wave propagations in the corresponding composite media were simulated.					
37030170	5	99	theme	experimental	991:1002	arg1	validations					1004:1014	analytical and experimental validations	976:1014	analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms	976:1108	In this study, we presented analytical and experimental validations of the proposed method using finite-element (FE) simulations and 3D-printed hydrogel phantoms, respectively.					
37030170	8	100	theme	Average	1654:1660	arg1	errors					1670:1675	Average percent errors	1654:1675	Average percent errors of (μf,μm,Vf) estimates	1654:1699	Average percent errors of (μf,μm,Vf) estimates were found to be (2.7%,7.3%,2.4%)in silico and (3.0%,8.0%,9.9%)in vitro.					
37030170	3	101	theme	wave	543:546	arg1	propagation					548:558	shear wave propagation	537:558	shear wave propagation	537:558	We have previously regarded the skeletal muscle as a composite of myofibers and extracellular matrix (ECM), formulated shear wave propagation in the undeformed muscle using the acoustoelastic theory, and preliminarily demonstrated that ultrasound-based shear wave elastography (SWE) could estimate microstructure-related material parameters (MRMPs): myofiber stiffness μf, ECM stiffness μm, and myofiber volume ratio Vf.					
35304201	4	0	theme	smallest	876:883	arg1	size					885:888	the smallest size	872:888	the smallest size of zein aggregates	872:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	1	1	theme	addition	160:167	arg1	effect					146:151	the effect	142:151	the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder	142:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	5	2	theme	transition	965:974	arg1	Tg					989:990	Tg	989:990	Tg	989:990	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	2	theme	transition	965:974	arg1	temperature					976:986	glass transition temperature	959:986	glass transition temperature (Tg)	959:991	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	2	3	theme	glycerol-plasticized	379:398	arg1	ratio					421:425	3:1 ratio	417:425	3:1 ratio	417:425	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	3	theme	glycerol-plasticized	379:398	arg1	starch					400:405	glycerol-plasticized starch	379:405	glycerol-plasticized starch	379:405	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	8	4	theme	0.2 M	1488:1492	arg1	NaOH					1494:1497	0.2 M NaOH	1488:1497	0.2 M NaOH	1488:1497	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	4	5	theme	zein	793:796	arg1	aggregates					798:807	zein aggregates	793:807	zein aggregates within the starch-zein composite films	793:846	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	8	6	theme	improved	1406:1413	arg1	elongation					1415:1424	improved elongation	1406:1424	improved elongation	1406:1424	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	2	7	theme	starch-zein	316:326	arg1	films					338:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	4	8	theme	NaOH	754:757	arg1	concentration					759:771	NaOH concentration	754:771	NaOH concentration	754:771	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	3	9	theme	Electron	540:547	arg1	Microscope					549:558	Scanning Electron Microscope	531:558	Scanning Electron Microscope	531:558	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	0	10	theme	alkaline	98:105	arg1	conditions					107:116	alkaline conditions	98:116	alkaline conditions	98:116	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	2	11	theme	Thermoplastic	302:314	arg1	films					338:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	12	theme	starch	400:405	arg1	extrusion					366:374	melt extrusion	361:374	melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	361:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	5	13	from	modulus	1005:1011	arg1	Tg					989:990	Tg	989:990	Tg	989:990	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	13	from	modulus	1005:1011	arg1	temperature					976:986	glass transition temperature	959:986	glass transition temperature (Tg)	959:991	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	1	14	theme	twin-screw	281:290	arg1	extruder					292:299	a twin-screw extruder	279:299	a twin-screw extruder	279:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	5	15	theme	starch	1092:1097	arg1	mobility					1051:1058	more molecular chain mobility	1030:1058	more molecular chain mobility	1030:1058	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	15	theme	starch	1092:1097	arg1	plasticization					1074:1087	efficient plasticization	1064:1087	efficient plasticization of starch and zein	1064:1106	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	4	16	theme	0.2 M	854:858	arg1	NaOH					860:863	0.2 M NaOH	854:863	0.2 M NaOH having the smallest size of zein aggregates	854:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	2	17	theme	different	441:449	arg1	concentrations					451:464	different concentrations	441:464	different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	441:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	6	18	theme	Infrared	1179:1186	arg1	FTIR					1202:1205	FTIR	1202:1205	FTIR	1202:1205	This efficient plasticization was also confirmed by Fourier-Transform Infrared spectroscopy (FTIR).					
35304201	6	18	theme	Infrared	1179:1186	arg1	spectroscopy					1188:1199	Fourier-Transform Infrared spectroscopy	1161:1199	Fourier-Transform Infrared spectroscopy (FTIR)	1161:1206	This efficient plasticization was also confirmed by Fourier-Transform Infrared spectroscopy (FTIR).					
35304201	1	19	theme	NaOH	172:175	arg1	addition					160:167	the addition	156:167	the addition of NaOH	156:175	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	8	20	theme	twin-screw	1458:1467	arg1	extruder					1469:1476	a twin-screw extruder	1456:1476	a twin-screw extruder	1456:1476	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	5	21	theme	Dynamic	910:916	arg1	analysis					929:936	Dynamic mechanical analysis	910:936	Dynamic mechanical analysis	910:936	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	6	22	theme	Fourier-Transform	1161:1177	arg1	FTIR					1202:1205	FTIR	1202:1205	FTIR	1202:1205	This efficient plasticization was also confirmed by Fourier-Transform Infrared spectroscopy (FTIR).					
35304201	6	22	theme	Fourier-Transform	1161:1177	arg1	spectroscopy					1188:1199	Fourier-Transform Infrared spectroscopy	1161:1199	Fourier-Transform Infrared spectroscopy (FTIR)	1161:1206	This efficient plasticization was also confirmed by Fourier-Transform Infrared spectroscopy (FTIR).					
35304201	5	23	theme	storage	997:1003	arg1	modulus					1005:1011	storage modulus	997:1011	storage modulus (E')	997:1016	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	23	theme	storage	997:1003	arg1	E					1014:1014	E'	1014:1015	E'	1014:1015	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	24	theme	zein	1103:1106	arg1	mobility					1051:1058	more molecular chain mobility	1030:1058	more molecular chain mobility	1030:1058	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	24	theme	zein	1103:1106	arg1	plasticization					1074:1087	efficient plasticization	1064:1087	efficient plasticization of starch and zein	1064:1106	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	8	25	theme	thermoplastic	1359:1371	arg1	films					1395:1399	compatible thermoplastic starch-zein composite films	1348:1399	compatible thermoplastic starch-zein composite films with improved elongation at break	1348:1433	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	1	26	from	effect	146:151	arg1	properties					211:220	the compatibility and material properties	180:220	the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder	180:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	3	27	theme	Confocal	564:571	arg1	Microscope					588:597	Confocal laser Scanning Microscope	564:597	Confocal laser Scanning Microscope	564:597	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	2	28	theme	3:1	417:419	arg1	ratio					421:425	3:1 ratio	417:425	3:1 ratio	417:425	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	28	theme	3:1	417:419	arg1	starch					400:405	glycerol-plasticized starch	379:405	glycerol-plasticized starch	379:405	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	29	theme	hydroxide	476:484	arg1	concentrations					451:464	different concentrations	441:464	different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	441:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	8	30	with	films	1395:1399	arg1	elongation					1415:1424	improved elongation	1406:1424	improved elongation	1406:1424	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	5	31	theme	chain	1045:1049	arg1	mobility					1051:1058	more molecular chain mobility	1030:1058	more molecular chain mobility	1030:1058	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	3	32	theme	laser	573:577	arg1	Microscope					588:597	Confocal laser Scanning Microscope	564:597	Confocal laser Scanning Microscope	564:597	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	1	33	theme	compatibility	184:196	arg1	properties					211:220	the compatibility and material properties	180:220	the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder	180:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	0	34	theme	maize	28:32	arg1	films					56:60	thermoplastic maize starch-zein composite films	14:60	thermoplastic maize starch-zein composite films prepared by extrusion	14:82	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	4	35	from	increase	742:749	arg1	concentration					759:771	NaOH concentration	754:771	NaOH concentration	754:771	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	5	36	theme	glass	959:963	arg1	transition					965:974	glass transition	959:974	glass transition temperature (Tg)	959:991	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	8	37	theme	starch-zein	1373:1383	arg1	films					1395:1399	compatible thermoplastic starch-zein composite films	1348:1399	compatible thermoplastic starch-zein composite films with improved elongation at break	1348:1433	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	0	38	theme	thermoplastic	14:26	arg1	films					56:60	thermoplastic maize starch-zein composite films	14:60	thermoplastic maize starch-zein composite films prepared by extrusion	14:82	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	3	39	theme	phase-separated	649:663	arg1	morphology					665:674	a phase-separated morphology	647:674	a phase-separated morphology	647:674	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	2	40	theme	composite	328:336	arg1	films					338:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films	302:342	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	1	41	theme	material	202:209	arg1	properties					211:220	the compatibility and material properties	180:220	the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder	180:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	0	42	theme	composite	46:54	arg1	films					56:60	thermoplastic maize starch-zein composite films	14:60	thermoplastic maize starch-zein composite films prepared by extrusion	14:82	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	7	43	theme	optimal	1235:1241	arg1	increase					1243:1250	an optimal increase	1232:1250	an optimal increase of 28% in elongation	1232:1271	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	4	44	theme	composite	832:840	arg1	films					842:846	the starch-zein composite films	816:846	the starch-zein composite films	816:846	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	7	45	theme	starch-zein	1289:1299	arg1	film					1311:1314	the starch-zein composite film	1285:1314	the starch-zein composite film with 0.2 M NaOH	1285:1330	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	0	46	theme	starch-zein	34:44	arg1	films					56:60	thermoplastic maize starch-zein composite films	14:60	thermoplastic maize starch-zein composite films prepared by extrusion	14:82	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	5	47	theme	efficient	1064:1072	arg1	plasticization					1074:1087	efficient plasticization	1064:1087	efficient plasticization of starch and zein	1064:1106	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	2	48	theme	sodium	469:474	arg1	hydroxide					476:484	sodium hydroxide	469:484	sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	469:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	48	theme	sodium	469:474	arg1	NaOH					487:490	NaOH	487:490	NaOH	487:490	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	2	48	theme	sodium	469:474	arg1	NaOH					524:527	0 M, 0.05 M, 0.1 M, and 0.2 M NaOH	494:527	0 M, 0.05 M, 0.1 M, and 0.2 M NaOH	494:527	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	4	49	theme	aggregates	898:907	arg1	size					885:888	the smallest size	872:888	the smallest size of zein aggregates	872:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	3	50	theme	Scanning	579:586	arg1	Microscope					588:597	Confocal laser Scanning Microscope	564:597	Confocal laser Scanning Microscope	564:597	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	5	51	theme	mechanical	918:927	arg1	analysis					929:936	Dynamic mechanical analysis	910:936	Dynamic mechanical analysis	910:936	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	0	52	theme	films	56:60	arg1	Properties					0:9	Properties	0:9	Properties of thermoplastic maize starch-zein composite films prepared by extrusion	0:82	Properties of thermoplastic maize starch-zein composite films prepared by extrusion process under alkaline conditions.					
35304201	4	53	theme	zein	893:896	arg1	aggregates					898:907	zein aggregates	893:907	zein aggregates	893:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	3	54	theme	zein	687:690	arg1	aggregates					692:701	large zein aggregates	681:701	large zein aggregates within the starch matrix	681:726	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	8	55	theme	composite	1385:1393	arg1	films					1395:1399	compatible thermoplastic starch-zein composite films	1348:1399	compatible thermoplastic starch-zein composite films with improved elongation at break	1348:1433	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	7	56	theme	%	1257:1257	arg1	increase					1243:1250	an optimal increase	1232:1250	an optimal increase of 28% in elongation	1232:1271	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	6	57	theme	efficient	1114:1122	arg1	plasticization					1124:1137	This efficient plasticization	1109:1137	This efficient plasticization	1109:1137	This efficient plasticization was also confirmed by Fourier-Transform Infrared spectroscopy (FTIR).					
35304201	8	58	from	break	1429:1433	arg1	films					1395:1399	compatible thermoplastic starch-zein composite films	1348:1399	compatible thermoplastic starch-zein composite films with improved elongation at break	1348:1433	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	7	59	theme	composite	1301:1309	arg1	film					1311:1314	the starch-zein composite film	1285:1314	the starch-zein composite film with 0.2 M NaOH	1285:1330	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	4	60	theme	aggregates	798:807	arg1	size					785:788	the size	781:788	the size of zein aggregates within the starch-zein composite films	781:846	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	4	61	theme	starch-zein	820:830	arg1	films					842:846	the starch-zein composite films	816:846	the starch-zein composite films	816:846	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	2	62	theme	melt	361:364	arg1	extrusion					366:374	melt extrusion	361:374	melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	361:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	4	63	contain	having	865:870	arg1	NaOH					860:863	0.2 M NaOH	854:863	0.2 M NaOH having the smallest size of zein aggregates	854:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	4	63	contain	having	865:870	arg2	size					885:888	the smallest size	872:888	the smallest size of zein aggregates	872:907	However, the increase in NaOH concentration reduced the size of zein aggregates within the starch-zein composite films, with 0.2 M NaOH having the smallest size of zein aggregates.					
35304201	1	64	theme	thermoplastic	225:237	arg1	films					261:265	thermoplastic starch-zein composite films	225:265	thermoplastic starch-zein composite films produced by a twin-screw extruder	225:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	7	65	with	film	1311:1314	arg1	NaOH					1327:1330	0.2 M NaOH	1321:1330	0.2 M NaOH	1321:1330	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	5	66	theme	molecular	1035:1043	arg1	mobility					1051:1058	more molecular chain mobility	1030:1058	more molecular chain mobility	1030:1058	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	3	67	theme	Scanning	531:538	arg1	Microscope					549:558	Scanning Electron Microscope	531:558	Scanning Electron Microscope	531:558	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	7	68	from	increase	1243:1250	arg1	elongation					1262:1271	elongation	1262:1271	elongation	1262:1271	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	5	69	from	decrease	947:954	arg1	Tg					989:990	Tg	989:990	Tg	989:990	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	5	69	from	decrease	947:954	arg1	temperature					976:986	glass transition temperature	959:986	glass transition temperature (Tg)	959:991	Dynamic mechanical analysis showed a decrease in glass transition temperature (Tg) and storage modulus (E'), suggesting more molecular chain mobility and efficient plasticization of starch and zein.					
35304201	1	70	theme	starch-zein	239:249	arg1	films					261:265	thermoplastic starch-zein composite films	225:265	thermoplastic starch-zein composite films produced by a twin-screw extruder	225:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	3	71	theme	large	681:685	arg1	aggregates					692:701	large zein aggregates	681:701	large zein aggregates within the starch matrix	681:726	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	2	72	theme	zein	411:414	arg1	extrusion					366:374	melt extrusion	361:374	melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH)	361:528	Thermoplastic starch-zein composite films were produced by melt extrusion of glycerol-plasticized starch and zein (3:1 ratio) treated with different concentrations of sodium hydroxide (NaOH) (0 M, 0.05 M, 0.1 M, and 0.2 M NaOH).					
35304201	8	73	theme	compatible	1348:1357	arg1	films					1395:1399	compatible thermoplastic starch-zein composite films	1348:1399	compatible thermoplastic starch-zein composite films with improved elongation at break	1348:1433	In conclusion, compatible thermoplastic starch-zein composite films with improved elongation at break can be produced with a twin-screw extruder by adding 0.2 M NaOH.					
35304201	1	74	theme	composite	251:259	arg1	films					261:265	thermoplastic starch-zein composite films	225:265	thermoplastic starch-zein composite films produced by a twin-screw extruder	225:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
35304201	3	75	theme	starch	714:719	arg1	matrix					721:726	the starch matrix	710:726	the starch matrix	710:726	Scanning Electron Microscope and Confocal laser Scanning Microscope revealed that the composite without NaOH formed a phase-separated morphology with large zein aggregates within the starch matrix.					
35304201	7	76	theme	0.2 M	1321:1325	arg1	NaOH					1327:1330	0.2 M NaOH	1321:1330	0.2 M NaOH	1321:1330	As a result, there was an optimal increase of 28% in elongation at break in the starch-zein composite film with 0.2 M NaOH.					
35304201	1	77	theme	films	261:265	arg1	properties					211:220	the compatibility and material properties	180:220	the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder	180:299	This work investigates the effect of the addition of NaOH on the compatibility and material properties of thermoplastic starch-zein composite films produced by a twin-screw extruder.					
36965569	7	0	theme	CR	1183:1184	arg1	process					1172:1178	The adsorption process	1157:1178	The adsorption process of CR	1157:1184	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	9	1	theme	size-matching	1499:1511	arg1	effects					1513:1519	size-matching effects	1499:1519	size-matching effects	1499:1519	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	3	2	theme	maximum	423:429	arg1	capacities					442:451	The maximum adsorption capacities	419:451	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al)	419:501	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	3	2	theme	maximum	423:429	arg1	mg · g-1					513:520	607.7 mg · g-1	507:520	607.7 mg · g-1	507:520	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	5	3	dep	/CS	946:948	arg1	Al					943:944	Al	943:944	Al	943:944	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	4	theme	MIL-88A	934:940	arg1	/CS					946:948	MIL-88A (Al)/CS	934:948	MIL-88A (Al)/CS	934:948	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	0	5	theme	adsorption	134:143	arg1	mechanism					145:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	3	6	theme	adsorption	431:440	arg1	capacities					442:451	The maximum adsorption capacities	419:451	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al)	419:501	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	3	6	theme	adsorption	431:440	arg1	mg · g-1					513:520	607.7 mg · g-1	507:520	607.7 mg · g-1	507:520	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	9	7	theme	CR	1401:1402	arg1	removal					1390:1396	The removal	1386:1396	The removal of CR	1386:1402	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	0	8	theme	Preparation	99:109	arg1	mechanism					145:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	2	9	dep	materials	290:298	arg1	materials					290:298	The three materials	280:298	The three materials' crystal structure and surface morphology	280:340	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	2	9	dep	materials	290:298	arg1	structure					309:317	crystal structure	301:317	crystal structure	301:317	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	2	9	dep	materials	290:298	arg1	morphology					331:340	surface morphology	323:340	surface morphology	323:340	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	5	10	theme	1056	977:980	arg1	mg · g-1					982:989	1056 mg · g-1	977:989	1056 mg · g-1	977:989	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	11	theme	MIL-88A	917:923	arg1	/CS					929:931	MIL-88A (Fe)/CS	917:931	MIL-88A (Fe)/CS	917:931	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	9	12	theme	metal	1467:1471	arg1	effects					1486:1492	metal coordination effects	1467:1492	metal coordination effects	1467:1492	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	7	13	theme	adsorption	1161:1170	arg1	process					1172:1178	The adsorption process	1157:1178	The adsorption process of CR	1157:1184	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	4	14	theme	CR	840:841	arg1	ability					829:835	the removal ability	817:835	the removal ability of CR	817:841	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	6	15	dep	structure	1046:1054	arg1	The					1042:1044	The	1042:1044	The	1042:1044	The structure and physicochemical properties of the materials were analyzed by SEM, FTIR, XRD, TGA, BET, and Zeta.					
36965569	9	16	theme	electrostatic	1421:1433	arg1	interactions					1435:1446	electrostatic interactions	1421:1446	electrostatic interactions	1421:1446	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	5	17	theme	Fe	926:927	arg1	/CS					929:931	MIL-88A (Fe)/CS	917:931	MIL-88A (Fe)/CS	917:931	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	4	18	theme	freeze-drying	691:703	arg1	method					705:710	the freeze-drying method	687:710	the freeze-drying method	687:710	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	6	19	theme	materials	1094:1102	arg1	properties					1076:1085	physicochemical properties	1060:1085	physicochemical properties	1060:1085	The structure and physicochemical properties of the materials were analyzed by SEM, FTIR, XRD, TGA, BET, and Zeta.					
36965569	6	19	theme	materials	1094:1102	arg1	structure					1046:1054	structure	1046:1054	structure	1046:1054	The structure and physicochemical properties of the materials were analyzed by SEM, FTIR, XRD, TGA, BET, and Zeta.					
36965569	0	20	theme	Efficient	0:8	arg1	adsorption					10:19	Efficient adsorption	0:19	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)	0:70	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	2	21	theme	surface	323:329	arg1	materials					290:298	The three materials	280:298	The three materials' crystal structure and surface morphology	280:340	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	2	21	theme	surface	323:329	arg1	morphology					331:340	surface morphology	323:340	surface morphology	323:340	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	2	22	theme	adsorption	378:387	arg1	properties					389:398	different adsorption properties	368:398	different adsorption properties of Congo red (CR)	368:416	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	9	23	theme	coordination	1473:1484	arg1	effects					1486:1492	metal coordination effects	1467:1492	metal coordination effects	1467:1492	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	9	24	theme	hydrogen	1449:1456	arg1	bonding					1458:1464	hydrogen bonding	1449:1464	hydrogen bonding	1449:1464	The removal of CR is attributed to electrostatic interactions, hydrogen bonding, metal coordination effects, and size-matching effects.					
36965569	3	25	theme	FeAl	479:482	arg1	capacities					442:451	The maximum adsorption capacities	419:451	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al)	419:501	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	3	25	theme	FeAl	479:482	arg1	mg · g-1					513:520	607.7 mg · g-1	507:520	607.7 mg · g-1	507:520	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	1	26	theme	MIL-88A	156:162	arg1	crystals					164:171	MIL-88A crystals	156:171	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl)	156:221	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	2	27	theme	different	368:376	arg1	properties					389:398	different adsorption properties	368:398	different adsorption properties of Congo red (CR)	368:416	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	5	28	theme	CS	955:956	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	28	theme	CS	955:956	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	0	29	theme	sponge	91:96	arg1	mechanism					145:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	8	30	theme	adsorption	1302:1311	arg1	adsorption					1374:1383	endothermic monomolecular chemical adsorption	1339:1383	endothermic monomolecular chemical adsorption	1339:1383	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	8	30	theme	adsorption	1302:1311	arg1	behavior					1313:1320	the adsorption behavior	1298:1320	the adsorption behavior	1298:1320	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	0	31	theme	composite	81:89	arg1	mechanism					145:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	5	32	theme	FeAl	907:910	arg1	/CS					912:914	MIL-88A (FeAl)/CS	898:914	MIL-88A (FeAl)/CS	898:914	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	1	33	with	crystals	164:171	arg1	ligands					200:206	three different metal ligands	178:206	three different metal ligands (Fe, Al, FeAl)	178:221	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	0	34	dep	MIL-88A	48:54	arg1	Fe-Al					65:69	Fe-Al	65:69	Fe-Al	65:69	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	0	34	dep	MIL-88A	48:54	arg1	Al					61:62	Al	61:62	Al	61:62	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	0	34	dep	MIL-88A	48:54	arg1	Fe					57:58	Fe	57:58	Fe	57:58	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	0	35	theme	red	30:32	arg1	adsorption					10:19	Efficient adsorption	0:19	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)	0:70	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	1	36	theme	hydrothermal	240:251	arg1	method					253:258	hydrothermal method	240:258	hydrothermal method for the first time	240:277	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	2	37	theme	red	409:411	arg1	properties					389:398	different adsorption properties	368:398	different adsorption properties of Congo red (CR)	368:416	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	5	38	theme	/CS	912:914	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	38	theme	/CS	912:914	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	3	39	theme	MIL-88A	490:496	arg1	capacities					442:451	The maximum adsorption capacities	419:451	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al)	419:501	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	3	39	theme	MIL-88A	490:496	arg1	mg · g-1					513:520	607.7 mg · g-1	507:520	607.7 mg · g-1	507:520	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	1	40	theme	different	184:192	arg1	ligands					200:206	three different metal ligands	178:206	three different metal ligands (Fe, Al, FeAl)	178:221	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	0	41	theme	characterization	112:127	arg1	mechanism					145:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	composite sponge: Preparation, characterization, and adsorption mechanism	81:153	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	1	42	dep	ligands	200:206	arg1	Al					213:214	Al	213:214	Al	213:214	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	1	42	dep	ligands	200:206	arg1	Fe					209:210	Fe	209:210	Fe	209:210	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	1	42	dep	ligands	200:206	arg1	FeAl					217:220	FeAl	217:220	FeAl	217:220	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	5	43	theme	maximum	865:871	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	43	theme	maximum	865:871	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	8	44	theme	thermodynamic	1272:1284	arg1	parameters					1286:1295	thermodynamic parameters	1272:1295	thermodynamic parameters	1272:1295	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	0	45	theme	micro/nano	37:46	arg1	MIL-88A					48:54	micro/nano MIL-88A	37:54	micro/nano MIL-88A (Fe, Al, Fe-Al)	37:70	Efficient adsorption of Congo red by micro/nano MIL-88A (Fe, Al, Fe-Al)/chitosan composite sponge: Preparation, characterization, and adsorption mechanism.					
36965569	5	46	theme	/CS	946:948	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	46	theme	/CS	946:948	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	47	theme	/CS	929:931	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	47	theme	/CS	929:931	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	7	48	theme	isotherm	1242:1249	arg1	kinetics					1214:1221	kinetics	1214:1221	kinetics	1214:1221	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	7	48	theme	isotherm	1242:1249	arg1	model					1251:1255	Sips isotherm model	1237:1255	Sips isotherm model	1237:1255	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	5	49	theme	adsorption	873:882	arg1	capacities					884:893	The maximum adsorption capacities	861:893	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS	861:956	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	5	49	theme	adsorption	873:882	arg1	mg · g-1					967:974	1312 mg · g-1	962:974	1312 mg · g-1	962:974	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	4	50	dep	solved	728:733	arg1	improved					808:815	improved	808:815	improved the removal ability of CR by the adsorbent	808:858	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	6	51	theme	physicochemical	1060:1074	arg1	properties					1076:1085	physicochemical properties	1060:1085	physicochemical properties	1060:1085	The structure and physicochemical properties of the materials were analyzed by SEM, FTIR, XRD, TGA, BET, and Zeta.					
36965569	4	52	theme	MIL-88A/CS	643:652	arg1	sponge					664:669	MIL-88A/CS composite sponge	643:669	MIL-88A/CS composite sponge	643:669	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	3	53	dep	Fe	465:466	arg1	Al					499:500	Al	499:500	Al	499:500	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	1	54	theme	metal	194:198	arg1	ligands					200:206	three different metal ligands	178:206	three different metal ligands (Fe, Al, FeAl)	178:221	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	4	55	theme	MIL-88A	751:757	arg1	powder					759:764	MIL-88A powder	751:764	MIL-88A powder	751:764	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	5	56	theme	MIL-88A	898:904	arg1	/CS					912:914	MIL-88A (FeAl)/CS	898:914	MIL-88A (FeAl)/CS	898:914	The maximum adsorption capacities of MIL-88A (FeAl)/CS, MIL-88A (Fe)/CS, MIL-88A (Al)/CS, and CS are 1312 mg · g-1, 1056 mg · g-1, 996.7 mg · g-1, and 769.6 mg · g-1, respectively.					
36965569	3	57	theme	Fe	465:466	arg1	capacities					442:451	The maximum adsorption capacities	419:451	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al)	419:501	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	3	57	theme	Fe	465:466	arg1	mg · g-1					513:520	607.7 mg · g-1	507:520	607.7 mg · g-1	507:520	The maximum adsorption capacities of MIL-88A (Fe), MIL-88A (FeAl), and MIL-88A (Al) are 607.7 mg · g-1, 536.4 mg · g-1, and 512.1 mg · g-1 respectively.					
36965569	8	58	theme	endothermic	1339:1349	arg1	adsorption					1374:1383	endothermic monomolecular chemical adsorption	1339:1383	endothermic monomolecular chemical adsorption	1339:1383	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	8	58	theme	endothermic	1339:1349	arg1	behavior					1313:1320	the adsorption behavior	1298:1320	the adsorption behavior	1298:1320	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	4	59	theme	removal	821:827	arg1	ability					829:835	the removal ability	817:835	the removal ability of CR	817:841	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	7	60	theme	Sips	1237:1240	arg1	kinetics					1214:1221	kinetics	1214:1221	kinetics	1214:1221	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	7	60	theme	Sips	1237:1240	arg1	model					1251:1255	Sips isotherm model	1237:1255	Sips isotherm model	1237:1255	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	2	61	theme	crystal	301:307	arg1	materials					290:298	The three materials	280:298	The three materials' crystal structure and surface morphology	280:340	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	2	61	theme	crystal	301:307	arg1	structure					309:317	crystal structure	301:317	crystal structure	301:317	The three materials' crystal structure and surface morphology are different, leading to different adsorption properties of Congo red (CR).					
36965569	7	62	theme	pseudo-second-order	1194:1212	arg1	kinetics					1214:1221	kinetics	1214:1221	kinetics	1214:1221	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	7	62	theme	pseudo-second-order	1194:1212	arg1	model					1251:1255	Sips isotherm model	1237:1255	Sips isotherm model	1237:1255	The adsorption process of CR follows pseudo-second-order kinetics and Langmuir, Sips isotherm model.					
36965569	1	63	theme	first	268:272	arg1	time					274:277	the first time	264:277	the first time	264:277	MIL-88A crystals with three different metal ligands (Fe, Al, FeAl) were prepared by hydrothermal method for the first time.					
36965569	4	64	theme	composite	654:662	arg1	sponge					664:669	MIL-88A/CS composite sponge	643:669	MIL-88A/CS composite sponge	643:669	In addition, MIL-88A was combined with chitosan (CS) respectively, and MIL-88A/CS composite sponge was prepared by the freeze-drying method, which not only solved the defect that MIL-88A powder was difficult to recover but also further improved the removal ability of CR by the adsorbent.					
36965569	8	65	theme	monomolecular	1351:1363	arg1	adsorption					1374:1383	endothermic monomolecular chemical adsorption	1339:1383	endothermic monomolecular chemical adsorption	1339:1383	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	8	65	theme	monomolecular	1351:1363	arg1	behavior					1313:1320	the adsorption behavior	1298:1320	the adsorption behavior	1298:1320	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	8	66	theme	chemical	1365:1372	arg1	adsorption					1374:1383	endothermic monomolecular chemical adsorption	1339:1383	endothermic monomolecular chemical adsorption	1339:1383	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
36965569	8	66	theme	chemical	1365:1372	arg1	behavior					1313:1320	the adsorption behavior	1298:1320	the adsorption behavior	1298:1320	Combined with thermodynamic parameters, the adsorption behavior was described as endothermic monomolecular chemical adsorption.					
35526359	5	0	theme	ABu	853:855	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	0	theme	ABu	853:855	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	1	1	theme	Fusobacterium	167:179	arg1	bacterium					207:215	an anaerobic bacterium	194:215	an anaerobic bacterium found in the human mouth where it causes periodontitis	194:270	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	1	1	theme	Fusobacterium	167:179	arg1	nucleatum					181:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	5	2	theme	sugar	672:676	arg1	chain					678:682	the same sugar chain	663:682	the same sugar chain	663:682	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	3	theme	pyranose	976:983	arg1	form					985:988	the pyranose form	972:988	the pyranose form	972:988	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	4	theme	strains	1347:1353	arg1	LPS					1340:1342	the LPS	1336:1342	the LPS of strains SB-106CP and HM-992 confirming the structural differentiation	1336:1415	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	5	dep	strains	1347:1353	arg1	strains					1347:1353	strains SB-106CP and HM-992	1347:1373	strains SB-106CP and HM-992 confirming the structural differentiation	1347:1415	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	5	dep	strains	1347:1353	arg1	HM-992					1368:1373	HM-992	1368:1373	HM-992	1368:1373	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	5	dep	strains	1347:1353	arg1	SB-106CP					1355:1362	SB-106CP	1355:1362	SB-106CP	1355:1362	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	0	6	theme	immunological	108:120	arg1	comparison					122:131	immunological comparison	108:131	immunological comparison to the O-antigen of strain 12230	108:164	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	4	7	theme	O-chain	534:540	arg1	structures					497:506	the structures	493:506	the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992,	493:599	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	2	8	theme	colorectal	294:303	arg1	tissues					312:318	colorectal cancer tissues	294:318	colorectal cancer tissues	294:318	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	6	9	theme	different	1171:1179	arg1	pattern					1191:1197	a different acylation pattern	1169:1197	a different acylation pattern	1169:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	0	10	from	nucleatum	66:74	arg1	Structure					0:8	Structure	0:8	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum	0:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	5	11	theme	same	667:670	arg1	chain					678:682	the same sugar chain	663:682	the same sugar chain	663:682	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	12	theme	mouse	1252:1256	arg1	antibody					1269:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody	1200:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen	1200:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	13	theme	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc-	730:783	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	13	theme	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc-	730:783	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	4	14	dep	F.	566:567	arg1	nucleatum					569:577	F. nucleatum	566:577	F. nucleatum	566:577	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	6	15	from	F.	1045:1046	arg1	structure					1019:1027	the structure	1015:1027	the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern	1015:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	15	from	F.	1045:1046	arg1	OPS					1036:1038	the OPS	1032:1038	the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern	1032:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	16	theme	-3-N-acetyl-3-aminobutyryl	890:915	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	17	theme	A	1250:1250	arg1	antibody					1269:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody	1200:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen	1200:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	18	theme	R	860:860	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	18	theme	R	860:860	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	19	theme	SB-106CP	785:792	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	19	theme	SB-106CP	785:792	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	20	contain	had	1096:1098	arg2	chain					1114:1118	similar sugar chain	1100:1118	similar sugar chain	1100:1118	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	20	contain	had	1096:1098	arg1	12230					1058:1062	12230	1058:1062	12230	1058:1062	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	21	theme	=	885:885	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	21	theme	=	885:885	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	22	theme	R	924:924	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	3	23	theme	Cell	400:403	arg1	structures					413:422	Cell surface structures	400:422	Cell surface structures of the bacterium	400:439	Cell surface structures of the bacterium could be implicated in pathogenesis.					
35526359	4	24	dep	report	486:491	arg1	both					601:604	both	601:604	both	601:604	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	1	25	theme	anaerobic	197:205	arg1	bacterium					207:215	an anaerobic bacterium	194:215	an anaerobic bacterium found in the human mouth where it causes periodontitis	194:270	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	1	25	theme	anaerobic	197:205	arg1	nucleatum					181:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	3	26	theme	surface	405:411	arg1	structures					413:422	Cell surface structures	400:422	Cell surface structures of the bacterium	400:439	Cell surface structures of the bacterium could be implicated in pathogenesis.					
35526359	6	27	theme	OPS	1036:1038	arg1	structure					1019:1027	the structure	1015:1027	the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern	1015:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	28	theme	-3-hydroxy-butyryl	926:943	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	0	29	theme	lipopolysaccharide	17:34	arg1	O-antigens					36:45	the lipopolysaccharide O-antigens	13:45	the lipopolysaccharide O-antigens	13:45	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	4	30	theme	strains	555:561	arg1	OPS					543:545	OPS	543:545	OPS	543:545	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	4	30	theme	strains	555:561	arg1	O-chain					534:540	the lipopolysaccharide O-chain	511:540	the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992,	511:599	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	6	31	theme	acylation	1181:1189	arg1	pattern					1191:1197	a different acylation pattern	1169:1197	a different acylation pattern	1169:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	32	theme	similar	1100:1106	arg1	chain					1114:1118	similar sugar chain	1100:1118	similar sugar chain	1100:1118	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	33	from	structure	1019:1027	arg1	F.					1045:1046	F.	1045:1046	F.	1045:1046	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	33	from	structure	1019:1027	arg1	isolate					1081:1087	a transtracheal isolate	1065:1087	a transtracheal isolate	1065:1087	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	34	with	pattern	1191:1197	arg1	Glc					1161:1163	Glc	1161:1163	Glc	1161:1163	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	2	35	theme	cancer	305:310	arg1	tissues					312:318	colorectal cancer tissues	294:318	colorectal cancer tissues	294:318	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	4	36	theme	cancerous	620:628	arg1	tissues					630:636	cancerous tissues	620:636	cancerous tissues	620:636	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	4	37	theme	F.	566:567	arg1	HM-992					593:598	HM-992	593:598	HM-992	593:598	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	4	37	theme	F.	566:567	arg1	SB-106CP					580:587	SB-106CP	580:587	SB-106CP	580:587	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	4	37	theme	F.	566:567	arg1	strains					555:561	two strains	551:561	two strains of F. nucleatum	551:577	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	0	38	theme	strain	153:158	arg1	O-antigen					140:148	the O-antigen	136:148	the O-antigen of strain 12230	136:164	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	5	39	theme	N-acylation	709:719	arg1	pattern					721:727	their N-acylation pattern	703:727	their N-acylation pattern	703:727	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	40	theme	sugar	1108:1112	arg1	chain					1114:1118	similar sugar chain	1100:1118	similar sugar chain	1100:1118	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	41	theme	HBu	917:919	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	0	42	theme	O-antigens	36:45	arg1	Structure					0:8	Structure	0:8	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum	0:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	3	43	theme	bacterium	431:439	arg1	structures					413:422	Cell surface structures	400:422	Cell surface structures of the bacterium	400:439	Cell surface structures of the bacterium could be implicated in pathogenesis.					
35526359	1	44	theme	human	230:234	arg1	mouth					236:240	the human mouth	226:240	the human mouth where it causes periodontitis	226:270	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	5	45	theme	-3-amino-butyryl	862:877	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	45	theme	-3-amino-butyryl	862:877	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	46	dep	cross	1319:1323	arg1	react					1325:1329	react	1325:1329	react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation	1325:1415	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	47	theme	GlcNAc	1149:1154	arg1	pattern					1191:1197	a different acylation pattern	1169:1197	a different acylation pattern	1169:1197	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	47	theme	GlcNAc	1149:1154	arg1	replacement					1134:1144	replacement	1134:1144	replacement of GlcNAc with Glc	1134:1163	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	0	48	theme	Fusobacterium	52:64	arg1	nucleatum					66:74	Fusobacterium nucleatum	52:74	Fusobacterium nucleatum	52:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230.					
35526359	6	49	dep	F.	1045:1046	arg1	nucleatum					1048:1056	F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern	1045:1197	nucleatum	1048:1056	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	49	dep	F.	1045:1046	arg1	12230					1058:1062	12230	1058:1062	12230	1058:1062	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	50	theme	12230	1295:1299	arg1	O-antigen					1301:1309	the 12230 O-antigen	1291:1309	the 12230 O-antigen	1291:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	2	51	theme	pregnancy	339:347	arg1	stillbirths					387:397	stillbirths	387:397	stillbirths	387:397	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	2	51	theme	pregnancy	339:347	arg1	complications					349:361	pregnancy complications	339:361	pregnancy complications	339:361	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	2	51	theme	pregnancy	339:347	arg1	pre-term					374:381	pre-term	374:381	pre-term	374:381	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	2	52	located	found	285:289	arg1	tissues					312:318	colorectal cancer tissues	294:318	colorectal cancer tissues	294:318	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	2	52	located	found	285:289	arg2	It					273:274	It	273:274	It	273:274	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
35526359	1	53	located	found	217:221	arg2	nucleatum					181:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum	167:189	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	1	53	located	found	217:221	arg1	mouth					236:240	the human mouth	226:240	the human mouth where it causes periodontitis	226:270	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	1	53	located	found	217:221	arg2	bacterium					207:215	an anaerobic bacterium	194:215	an anaerobic bacterium found in the human mouth where it causes periodontitis	194:270	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
35526359	6	54	with	replacement	1134:1144	arg1	Glc					1161:1163	Glc	1161:1163	Glc	1161:1163	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	55	theme	structural	1390:1399	arg1	differentiation					1401:1415	the structural differentiation	1386:1415	the structural differentiation	1386:1415	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	56	theme	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu-	1200:1248	arg1	antibody					1269:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody	1200:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen	1200:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	57	theme	monoclonal	1258:1267	arg1	antibody					1269:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody	1200:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen	1200:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	58	theme	=	857:857	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	58	theme	=	857:857	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	59	theme	transtracheal	1067:1079	arg1	F.					1045:1046	F.	1045:1046	F.	1045:1046	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	6	59	theme	transtracheal	1067:1079	arg1	isolate					1081:1087	a transtracheal isolate	1065:1087	a transtracheal isolate	1065:1087	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	60	theme	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc-	794:844	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	60	theme	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc-	794:844	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	61	theme	=	921:921	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	6	62	theme	specific	1278:1285	arg1	antibody					1269:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody	1200:1276	-6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen	1200:1309	Previously we published the structure of the OPS from F. nucleatum 12230, a transtracheal isolate, which had similar sugar chain, differing by replacement of GlcNAc with Glc and a different acylation pattern: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- A mouse monoclonal antibody specific for the 12230 O-antigen did not cross react with the LPS of strains SB-106CP and HM-992 confirming the structural differentiation.					
35526359	5	63	theme	All	945:947	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	64	theme	HM-992	846:851	arg1	AbuAc					879:883	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc =	730:885	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	5	64	theme	HM-992	846:851	arg1	R					888:888	R	888:888	R	888:888	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
35526359	4	65	theme	lipopolysaccharide	515:532	arg1	OPS					543:545	OPS	543:545	OPS	543:545	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	4	65	theme	lipopolysaccharide	515:532	arg1	O-chain					534:540	the lipopolysaccharide O-chain	511:540	the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992,	511:599	Here we report the structures of the lipopolysaccharide O-chain (OPS) of two strains of F. nucleatum, SB-106CP and HM-992, both isolated from cancerous tissues.					
35526359	5	66	theme	AbuAc	879:883	arg1	monosaccharides					949:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	-6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides	730:963	These strains elaborate the same sugar chain, differing only by their N-acylation pattern: -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NABuAc- SB-106CP -6-α-D-GlcNAc-4-β-D-GlcNHBu3NABuA-3-β-D-QuiNAc4NAc- HM-992 ABu = (R)-3-amino-butyryl AbuAc = (R)-3-N-acetyl-3-aminobutyryl HBu = (R)-3-hydroxy-butyryl All monosaccharides are in the pyranose form.					
36940874	5	0	theme	Peptoclostridium	842:857	arg1	abundance					829:837	the abundance	825:837	the abundance of Peptoclostridium	825:857	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	4	1	theme	humic	633:637	arg1	substances					639:648	humic substances	633:648	humic substances	633:648	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	7	2	theme	wastewater	1211:1220	arg1	digestion					1171:1179	anaerobic digestion	1161:1179	anaerobic digestion of high concentration organic wastewater under acid inhibition	1161:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	4	3	theme	characteristics	551:565	arg1	analysis					532:539	The analysis	528:539	The analysis of sludge characteristics	528:565	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	3	4	theme	methanogenesis	376:389	arg1	rate					391:394	the methanogenesis rate	372:394	the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times	372:462	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	4	5	theme	sludge	544:549	arg1	characteristics					551:565	sludge characteristics	544:565	sludge characteristics	544:565	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	7	6	theme	chitosan-Fe3O4	1093:1106	arg1	use					1086:1088	the use	1082:1088	the use of chitosan-Fe3O4	1082:1106	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	2	7	theme	acid	301:304	arg1	stress					306:311	acid stress	301:311	acid stress	301:311	Herein, chitosan-Fe3O4 was prepared, and its effects on anaerobic digestion processes under acid stress were studied.					
36940874	4	8	theme	substances	639:648	arg1	secretion					607:615	the secretion	603:615	the secretion of proteins and humic substances	603:648	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	5	9	theme	direct	893:898	arg1	transfer					922:929	direct interspecies electron transfer	893:929	direct interspecies electron transfer	893:929	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	4	10	theme	system	740:745	arg1	activity					724:731	the electron transfer activity	702:731	the electron transfer activity of the system	702:745	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	1	11	theme	low	173:175	arg1	efficiency					197:206	low anaerobic treatment efficiency	173:206	low anaerobic treatment efficiency	173:206	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	0	12	theme	liquor	57:62	arg1	wastewater					64:73	liquor wastewater	57:73	liquor wastewater	57:73	Chitosan-Fe3O4 composites enhance anaerobic digestion of liquor wastewater under acidic stress.					
36940874	2	13	theme	digestion	275:283	arg1	processes					285:293	anaerobic digestion processes	265:293	anaerobic digestion processes	265:293	Herein, chitosan-Fe3O4 was prepared, and its effects on anaerobic digestion processes under acid stress were studied.					
36940874	1	14	theme	anaerobic	177:185	arg1	efficiency					197:206	low anaerobic treatment efficiency	173:206	low anaerobic treatment efficiency	173:206	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	3	15	theme	digestion	409:417	arg1	rate					391:394	the methanogenesis rate	372:394	the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times	372:462	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	6	16	theme	transfer	994:1001	arg1	pathway					1003:1009	the direct interspecies electron transfer pathway	961:1009	the direct interspecies electron transfer pathway to maintain stable methanogenesis	961:1043	Chitosan-Fe3O4 could promote the direct interspecies electron transfer pathway to maintain stable methanogenesis.					
36940874	1	17	theme	Acid	96:99	arg1	stress					101:106	Acid stress	96:106	Acid stress in the anaerobic digestion process of liquor wastewater	96:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	1	18	theme	treatment	187:195	arg1	efficiency					197:206	low anaerobic treatment efficiency	173:206	low anaerobic treatment efficiency	173:206	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	0	19	theme	Chitosan-Fe3O4	0:13	arg1	composites					15:24	Chitosan-Fe3O4 composites	0:24	Chitosan-Fe3O4 composites	0:24	Chitosan-Fe3O4 composites enhance anaerobic digestion of liquor wastewater under acidic stress.					
36940874	7	20	theme	acid	1228:1231	arg1	inhibition					1233:1242	acid inhibition	1228:1242	acid inhibition	1228:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	2	21	from	effects	254:260	arg1	processes					285:293	anaerobic digestion processes	265:293	anaerobic digestion processes	265:293	Herein, chitosan-Fe3O4 was prepared, and its effects on anaerobic digestion processes under acid stress were studied.					
36940874	0	22	theme	anaerobic	34:42	arg1	digestion					44:52	anaerobic digestion	34:52	anaerobic digestion of liquor wastewater	34:73	Chitosan-Fe3O4 composites enhance anaerobic digestion of liquor wastewater under acidic stress.					
36940874	5	23	theme	interspecies	900:911	arg1	transfer					922:929	direct interspecies electron transfer	893:929	direct interspecies electron transfer	893:929	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	5	24	theme	Microbial	757:765	arg1	community					767:775	Microbial community	757:775	Microbial community analysis	757:784	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	3	25	theme	anaerobic	399:407	arg1	digestion					409:417	anaerobic digestion	399:417	anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times	399:462	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	4	26	theme	proteins	620:627	arg1	secretion					607:615	the secretion	603:615	the secretion of proteins and humic substances	603:648	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	5	27	theme	community	767:775	arg1	analysis					777:784	Microbial community analysis	757:784	Microbial community analysis	757:784	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	6	28	theme	electron	985:992	arg1	pathway					1003:1009	the direct interspecies electron transfer pathway	961:1009	the direct interspecies electron transfer pathway to maintain stable methanogenesis	961:1043	Chitosan-Fe3O4 could promote the direct interspecies electron transfer pathway to maintain stable methanogenesis.					
36940874	3	29	theme	acidified	499:507	arg1	systems					519:525	acidified anaerobic systems	499:525	acidified anaerobic systems	499:525	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	3	30	theme	wastewater	436:445	arg1	digestion					409:417	anaerobic digestion	399:417	anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times	399:462	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	7	31	theme	high	1184:1187	arg1	wastewater					1211:1220	high concentration organic wastewater	1184:1220	high concentration organic wastewater under acid inhibition	1184:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	6	32	theme	interspecies	972:983	arg1	pathway					1003:1009	the direct interspecies electron transfer pathway	961:1009	the direct interspecies electron transfer pathway to maintain stable methanogenesis	961:1043	Chitosan-Fe3O4 could promote the direct interspecies electron transfer pathway to maintain stable methanogenesis.					
36940874	4	33	theme	transfer	715:722	arg1	activity					724:731	the electron transfer activity	702:731	the electron transfer activity of the system	702:745	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	7	34	theme	concentration	1189:1201	arg1	wastewater					1211:1220	high concentration organic wastewater	1184:1220	high concentration organic wastewater under acid inhibition	1184:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	6	35	theme	direct	965:970	arg1	pathway					1003:1009	the direct interspecies electron transfer pathway	961:1009	the direct interspecies electron transfer pathway to maintain stable methanogenesis	961:1043	Chitosan-Fe3O4 could promote the direct interspecies electron transfer pathway to maintain stable methanogenesis.					
36940874	5	36	theme	electron	913:920	arg1	transfer					922:929	direct interspecies electron transfer	893:929	direct interspecies electron transfer	893:929	Microbial community analysis indicated that chitosan-Fe3O4 enriched the abundance of Peptoclostridium, and Methanosaeta participated in direct interspecies electron transfer.					
36940874	4	37	theme	electron	706:713	arg1	activity					724:731	the electron transfer activity	702:731	the electron transfer activity of the system	702:745	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	0	38	theme	wastewater	64:73	arg1	digestion					44:52	anaerobic digestion	34:52	anaerobic digestion of liquor wastewater	34:73	Chitosan-Fe3O4 composites enhance anaerobic digestion of liquor wastewater under acidic stress.					
36940874	7	39	theme	digestion	1171:1179	arg1	efficiency					1147:1156	the efficiency	1143:1156	the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition	1143:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	1	40	theme	anaerobic	115:123	arg1	process					135:141	the anaerobic digestion process	111:141	the anaerobic digestion process of liquor wastewater	111:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	3	41	theme	liquor	429:434	arg1	wastewater					436:445	acidic liquor wastewater	422:445	acidic liquor wastewater	422:445	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	7	42	theme	organic	1203:1209	arg1	wastewater					1211:1220	high concentration organic wastewater	1184:1220	high concentration organic wastewater under acid inhibition	1184:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	1	43	theme	digestion	125:133	arg1	process					135:141	the anaerobic digestion process	111:141	the anaerobic digestion process of liquor wastewater	111:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	2	44	theme	anaerobic	265:273	arg1	processes					285:293	anaerobic digestion processes	265:293	anaerobic digestion processes	265:293	Herein, chitosan-Fe3O4 was prepared, and its effects on anaerobic digestion processes under acid stress were studied.					
36940874	3	45	theme	anaerobic	509:517	arg1	systems					519:525	acidified anaerobic systems	499:525	acidified anaerobic systems	499:525	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	4	46	theme	polymeric	667:675	arg1	substances					677:686	extracellular polymeric substances	653:686	extracellular polymeric substances	653:686	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	7	47	theme	anaerobic	1161:1169	arg1	digestion					1171:1179	anaerobic digestion	1161:1179	anaerobic digestion of high concentration organic wastewater under acid inhibition	1161:1242	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
36940874	3	48	theme	systems	519:525	arg1	restoration					484:494	the restoration	480:494	the restoration of acidified anaerobic systems	480:525	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	4	49	theme	extracellular	653:665	arg1	substances					677:686	extracellular polymeric substances	653:686	extracellular polymeric substances	653:686	The analysis of sludge characteristics showed that chitosan-Fe3O4 promoted the secretion of proteins and humic substances in extracellular polymeric substances and increased the electron transfer activity of the system by 71.4%.					
36940874	0	50	theme	acidic	81:86	arg1	stress					88:93	acidic stress	81:93	acidic stress	81:93	Chitosan-Fe3O4 composites enhance anaerobic digestion of liquor wastewater under acidic stress.					
36940874	1	51	theme	liquor	146:151	arg1	wastewater					153:162	liquor wastewater	146:162	liquor wastewater	146:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	1	52	from	stress	101:106	arg1	process					135:141	the anaerobic digestion process	111:141	the anaerobic digestion process of liquor wastewater	111:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	6	53	theme	stable	1023:1028	arg1	methanogenesis					1030:1043	stable methanogenesis	1023:1043	stable methanogenesis	1023:1043	Chitosan-Fe3O4 could promote the direct interspecies electron transfer pathway to maintain stable methanogenesis.					
36940874	3	54	theme	acidic	422:427	arg1	wastewater					436:445	acidic liquor wastewater	422:445	acidic liquor wastewater	422:445	Results showed that chitosan-Fe3O4 increased the methanogenesis rate of anaerobic digestion of acidic liquor wastewater by 1.5-2.3 times and accelerated the restoration of acidified anaerobic systems.					
36940874	1	55	theme	wastewater	153:162	arg1	process					135:141	the anaerobic digestion process	111:141	the anaerobic digestion process of liquor wastewater	111:162	Acid stress in the anaerobic digestion process of liquor wastewater leads to low anaerobic treatment efficiency.					
36940874	7	56	dep	methods	1052:1058	arg1	These					1046:1050	These	1046:1050	These	1046:1050	These methods and results regarding the use of chitosan-Fe3O4 could be referred to for improving the efficiency of anaerobic digestion of high concentration organic wastewater under acid inhibition.					
35257726	6	0	theme	actual	1308:1313	arg1	requirements					1327:1338	actual application requirements	1308:1338	actual application requirements	1308:1338	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	1	1	theme	treatment	277:285	arg1	field					257:261	the field	253:261	the field of the sewage treatment	253:285	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	4	2	theme	three-dimensional	803:819	arg1	sponge					850:855	the three-dimensional (3D) highly porous composite sponge	799:855	the three-dimensional (3D) highly porous composite sponge	799:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	4	3	theme	electrostatic	697:709	arg1	interaction					711:721	the strong electrostatic interaction	686:721	the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge	686:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	2	4	theme	cellulose	314:322	arg1	CNF					336:338	CNF	336:338	CNF	336:338	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	2	4	theme	cellulose	314:322	arg1	nanofibril					324:333	anisotropic cellulose nanofibril	302:333	anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites	302:380	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	4	5	theme	exchange	760:767	arg1	property					769:776	good cation exchange property	748:776	good cation exchange property	748:776	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	0	6	theme	selective	110:118	arg1	separation					120:129	selective separation	110:129	selective separation	110:129	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	6	7	theme	dyes	1290:1293	arg1	treatment					1267:1275	the separation treatment	1252:1275	the separation treatment of different dyes according to actual application requirements	1252:1338	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	2	8	theme	anisotropic	302:312	arg1	CNF					336:338	CNF	336:338	CNF	336:338	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	2	8	theme	anisotropic	302:312	arg1	nanofibril					324:333	anisotropic cellulose nanofibril	302:333	anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites	302:380	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	3	9	theme	120.0 mg/g	540:549	arg1	120.0 mg/g					540:549	120.0 mg/g	540:549	120.0 mg/g	540:549	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	3	9	theme	120.0 mg/g	540:549	arg1	%					559:559	96.1%	555:559	96.1% for methylene blue (MB)	555:583	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	3	9	theme	120.0 mg/g	540:549	arg1	capacity					505:512	superior saturated adsorption capacity	475:512	superior saturated adsorption capacity	475:512	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	3	9	theme	120.0 mg/g	540:549	arg1	efficiency					526:535	removal efficiency	518:535	removal efficiency	518:535	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	5	10	theme	214.6 mg/g	1120:1129	arg1	capacity					1108:1115	a theoretical maximum adsorption capacity	1075:1115	a theoretical maximum adsorption capacity of 214.6 mg/g	1075:1129	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	6	11	theme	different	1280:1288	arg1	dyes					1290:1293	different dyes	1280:1293	different dyes according to actual application requirements	1280:1338	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	6	12	theme	anionic	1196:1202	arg1	dyes					1217:1220	anionic and cationic dyes	1196:1220	anionic and cationic dyes	1196:1220	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	1	13	theme	dye	208:210	arg1	contaminants					212:223	dye contaminants	208:223	dye contaminants	208:223	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	6	14	theme	selective	1162:1170	arg1	capacity					1183:1190	a selective adsorption capacity	1160:1190	a selective adsorption capacity	1160:1190	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	3	15	theme	adsorption	494:503	arg1	capacity					505:512	superior saturated adsorption capacity	475:512	superior saturated adsorption capacity	475:512	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	4	16	theme	cation	753:758	arg1	exchange					760:767	good cation exchange	748:767	good cation exchange property	748:776	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	4	17	theme	strong	690:695	arg1	interaction					711:721	the strong electrostatic interaction	686:721	the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge	686:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	0	18	theme	Lightweight	0:10	arg1	cellulose					28:36	Lightweight and anisotropic cellulose	0:36	Lightweight and anisotropic cellulose	0:36	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	6	19	theme	separation	1256:1265	arg1	treatment					1267:1275	the separation treatment	1252:1275	the separation treatment of different dyes according to actual application requirements	1252:1338	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	4	20	theme	good	748:751	arg1	exchange					760:767	good cation exchange	748:767	good cation exchange property	748:776	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	4	21	theme	rectorites	781:790	arg1	interaction					711:721	the strong electrostatic interaction	686:721	the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge	686:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	2	22	theme	directional	405:415	arg1	freeze-drying					417:429	directional freeze-drying	405:429	directional freeze-drying	405:429	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	5	23	theme	MB	862:863	arg1	process					876:882	The MB adsorption process	858:882	The MB adsorption process of the composite sponge	858:906	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	5	24	theme	isotherm	971:978	arg1	model					980:984	the Langmuir isotherm model	958:984	the Langmuir isotherm model	958:984	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	1	25	theme	great	231:235	arg1	significance					237:248	great significance	231:248	great significance	231:248	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	0	26	theme	anisotropic	16:26	arg1	cellulose					28:36	Lightweight and anisotropic cellulose	0:36	Lightweight and anisotropic cellulose	0:36	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	6	27	theme	cationic	1208:1215	arg1	dyes					1217:1220	anionic and cationic dyes	1196:1220	anionic and cationic dyes	1196:1220	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	5	28	theme	Langmuir	962:969	arg1	model					980:984	the Langmuir isotherm model	958:984	the Langmuir isotherm model	958:984	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	5	29	theme	theoretical	1077:1087	arg1	capacity					1108:1115	a theoretical maximum adsorption capacity	1075:1115	a theoretical maximum adsorption capacity of 214.6 mg/g	1075:1129	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	2	30	theme	nanofibril	324:333	arg1	sponges					351:357	anisotropic cellulose nanofibril (CNF) composite sponges	302:357	anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites	302:380	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	6	31	theme	adsorption	1172:1181	arg1	capacity					1183:1190	a selective adsorption capacity	1160:1190	a selective adsorption capacity	1160:1190	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	0	32	theme	composite	59:67	arg1	sponges					69:75	composite sponges	59:75	composite sponges for efficient dye adsorption and selective separation	59:129	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	5	33	theme	kinetic	940:946	arg1	model					948:952	the pseudo-second-order kinetic model	916:952	the pseudo-second-order kinetic model	916:952	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	5	34	theme	maximum	1089:1095	arg1	capacity					1108:1115	a theoretical maximum adsorption capacity	1075:1115	a theoretical maximum adsorption capacity of 214.6 mg/g	1075:1129	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	4	35	theme	porous	833:838	arg1	sponge					850:855	the three-dimensional (3D) highly porous composite sponge	799:855	the three-dimensional (3D) highly porous composite sponge	799:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	3	36	theme	superior	475:482	arg1	capacity					505:512	superior saturated adsorption capacity	475:512	superior saturated adsorption capacity	475:512	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	4	37	dep	three-dimensional	803:819	arg1	3D					822:823	3D	822:823	3D	822:823	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	3	38	theme	saturated	484:492	arg1	capacity					505:512	superior saturated adsorption capacity	475:512	superior saturated adsorption capacity	475:512	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	5	39	theme	adsorption	1097:1106	arg1	capacity					1108:1115	a theoretical maximum adsorption capacity	1075:1115	a theoretical maximum adsorption capacity of 214.6 mg/g	1075:1129	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	3	40	theme	pure	625:628	arg1	sponge					634:639	the pure CNF sponge and rectorite powders	621:661	sponge	634:639	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	5	41	theme	adsorption	865:874	arg1	process					876:882	The MB adsorption process	858:882	The MB adsorption process of the composite sponge	858:906	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	3	42	theme	resulted	436:443	arg1	sponge					455:460	The resulted composite sponge	432:460	The resulted composite sponge	432:460	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	6	43	contain	possesses	1150:1158	arg1	it					1142:1143	it	1142:1143	it	1142:1143	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	6	43	contain	possesses	1150:1158	arg2	capacity					1183:1190	a selective adsorption capacity	1160:1190	a selective adsorption capacity	1160:1190	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	5	44	theme	intraparticle	1037:1049	arg1	diffusion					1051:1059	intraparticle diffusion	1037:1059	intraparticle diffusion	1037:1059	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	1	45	theme	lightweight	145:155	arg1	adsorbents					168:177	lightweight and porous adsorbents	145:177	lightweight and porous adsorbents which can effectively remove dye contaminants	145:223	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	3	46	theme	composite	445:453	arg1	sponge					455:460	The resulted composite sponge	432:460	The resulted composite sponge	432:460	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	4	47	theme	composite	840:848	arg1	sponge					850:855	the three-dimensional (3D) highly porous composite sponge	799:855	the three-dimensional (3D) highly porous composite sponge	799:855	This is attributed to the strong electrostatic interaction between CNFs and MB, and good cation exchange property of rectorites inside the three-dimensional (3D) highly porous composite sponge.					
35257726	2	48	theme	assisted	359:366	arg1	sponges					351:357	anisotropic cellulose nanofibril (CNF) composite sponges	302:357	anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites	302:380	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	3	49	dep	capacity	505:512	arg1	the					471:473	the	471:473	the	471:473	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	1	50	from	significance	237:248	arg1	field					257:261	the field	253:261	the field of the sewage treatment	253:285	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	1	51	theme	porous	161:166	arg1	adsorbents					168:177	lightweight and porous adsorbents	145:177	lightweight and porous adsorbents which can effectively remove dye contaminants	145:223	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
35257726	5	52	theme	composite	891:899	arg1	sponge					901:906	the composite sponge	887:906	the composite sponge	887:906	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	6	53	theme	application	1315:1325	arg1	requirements					1327:1338	actual application requirements	1308:1338	actual application requirements	1308:1338	Moreover, it also possesses a selective adsorption capacity for anionic and cationic dyes, which is expected to realize the separation treatment of different dyes according to actual application requirements.					
35257726	5	54	theme	pseudo-second-order	920:938	arg1	model					948:952	the pseudo-second-order kinetic model	916:952	the pseudo-second-order kinetic model	916:952	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	3	55	theme	rectorite	645:653	arg1	powders					655:661	the pure CNF sponge and rectorite powders	621:661	powders	655:661	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	2	56	theme	composite	341:349	arg1	sponges					351:357	anisotropic cellulose nanofibril (CNF) composite sponges	302:357	anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites	302:380	In this work, anisotropic cellulose nanofibril (CNF) composite sponges assisted by rectorites are fabricated through directional freeze-drying.					
35257726	0	57	theme	dye	91:93	arg1	adsorption					95:104	efficient dye adsorption	81:104	efficient dye adsorption	81:104	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	3	58	theme	CNF	630:632	arg1	sponge					634:639	the pure CNF sponge and rectorite powders	621:661	sponge	634:639	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	3	59	theme	removal	518:524	arg1	efficiency					526:535	removal efficiency	518:535	removal efficiency	518:535	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	5	60	theme	sponge	901:906	arg1	process					876:882	The MB adsorption process	858:882	The MB adsorption process of the composite sponge	858:906	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	0	61	theme	efficient	81:89	arg1	adsorption					95:104	efficient dye adsorption	81:104	efficient dye adsorption	81:104	Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation.					
35257726	5	62	theme	boundary	1018:1025	arg1	layer					1027:1031	boundary layer	1018:1031	boundary layer	1018:1031	The MB adsorption process of the composite sponge fits to the pseudo-second-order kinetic model and the Langmuir isotherm model well, which is affected by both boundary layer and intraparticle diffusion, resulting in a theoretical maximum adsorption capacity of 214.6 mg/g.					
35257726	3	63	theme	blue	575:578	arg1	methylene					565:573	methylene blue	565:578	methylene blue (MB)	565:583	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	3	63	theme	blue	575:578	arg1	MB					581:582	MB	581:582	MB	581:582	The resulted composite sponge exhibits the superior saturated adsorption capacity and removal efficiency of 120.0 mg/g and 96.1% for methylene blue (MB), respectively, which is better than the pure CNF sponge and rectorite powders.					
35257726	1	64	theme	sewage	270:275	arg1	treatment					277:285	the sewage treatment	266:285	the sewage treatment	266:285	Constructing lightweight and porous adsorbents which can effectively remove dye contaminants is of great significance in the field of the sewage treatment.					
36542391	14	0	theme	biofilm	1946:1952	arg1	composition					1954:1964	biofilm composition	1946:1964	biofilm composition	1946:1964	Within the limitations imposed by this model, results from the present study underscore the potential for prebiotic inulin to modify biofilm composition favorably.					
36542391	5	1	theme	prebiotic	720:728	arg1	subsp					790:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	1	theme	prebiotic	720:728	arg1	inulin					730:735	prebiotic inulin	720:735	prebiotic inulin	720:735	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	7	2	from	biofilms	863:870	arg1	present					845:851	present	845:851	present	845:851	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	4	3	theme	lactis	422:427	arg1	supplementation					429:443	lactis supplementation	422:443	lactis supplementation with and without prebiotic inulin on biofilm composition	422:500	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	2	4	theme	Probiotic	157:165	arg1	supplementation					177:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	10	5	theme	L.	1380:1381	arg1	subsp					1406:1410	L. reuteri or B. animalis subsp	1380:1410	L. reuteri or B. animalis subsp	1380:1410	Inoculation with L. reuteri or B. animalis subsp.					
36542391	9	6	theme	dose-dependent	1114:1127	arg1	increases					1129:1137	statistically significant dose-dependent increases	1088:1137	statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001)	1088:1217	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	10	7	theme	B.	1394:1395	arg1	subsp					1406:1410	L. reuteri or B. animalis subsp	1380:1410	L. reuteri or B. animalis subsp	1380:1410	Inoculation with L. reuteri or B. animalis subsp.					
36542391	2	8	theme	health	290:295	arg1	maintenance					263:273	the maintenance	259:273	the maintenance of periodontal health	259:295	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	2	8	theme	health	290:295	arg1	treatment					228:236	the treatment	224:236	the treatment of periodontitis	224:253	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	5	9	theme	Subgingival	542:552	arg1	specimens					561:569	METHODS Subgingival plaque specimens	534:569	METHODS Subgingival plaque specimens from three periodontitis-affected human donors	534:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	13	10	dep	CONCLUSIONS	1611:1621	arg1	appears					1651:1657	appears	1651:1657	appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity	1651:1810	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	13	11	theme	biofilm	1777:1783	arg1	composition					1785:1795	biofilm composition	1777:1795	biofilm composition	1777:1795	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	15	12	theme	biologic	2017:2024	arg1	rationale					2026:2034	biologic rationale	2017:2034	biologic rationale	2017:2034	Additional research further elucidating biologic rationale and controlled clinical research defining therapeutic benefits is warranted.					
36542391	12	13	theme	biofilm	1574:1580	arg1	diversity					1588:1596	biofilm alpha diversity	1574:1596	biofilm alpha diversity (p < 0.001)	1574:1608	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	12	13	theme	biofilm	1574:1580	arg1	p < 0.001					1599:1607	p < 0.001	1599:1607	p < 0.001	1599:1607	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	14	14	theme	prebiotic	1919:1927	arg1	inulin					1929:1934	prebiotic inulin	1919:1934	prebiotic inulin	1919:1934	Within the limitations imposed by this model, results from the present study underscore the potential for prebiotic inulin to modify biofilm composition favorably.					
36542391	7	15	theme	next-generation	902:916	arg1	sequencing					918:927	16S rRNA next-generation sequencing	893:927	16S rRNA next-generation sequencing	893:927	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	4	16	theme	biofilm	482:488	arg1	composition					490:500	biofilm composition	482:500	biofilm composition	482:500	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	9	17	theme	Lactobacillus	1165:1177	arg1	p < 0.001					1208:1216	p < 0.001	1208:1216	p < 0.001	1208:1216	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	17	theme	Lactobacillus	1165:1177	arg1	species					1199:1205	Lactobacillus and Bifidobacterium species	1165:1205	species	1199:1205	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	2	18	theme	periodontitis	241:253	arg1	maintenance					263:273	the maintenance	259:273	the maintenance of periodontal health	259:295	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	2	18	theme	periodontitis	241:253	arg1	treatment					228:236	the treatment	224:236	the treatment of periodontitis	224:253	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	5	19	theme	human	605:609	arg1	donors					611:616	three periodontitis-affected human donors	576:616	three periodontitis-affected human donors	576:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	20	from	donors	611:616	arg1	specimens					561:569	METHODS Subgingival plaque specimens	534:569	METHODS Subgingival plaque specimens from three periodontitis-affected human donors	534:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	3	21	theme	investigation	318:330	arg1	purpose					302:308	The purpose	298:308	The purpose of this investigation	298:330	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	9	22	theme	Bifidobacterium	1183:1197	arg1	p < 0.001					1208:1216	p < 0.001	1208:1216	p < 0.001	1208:1216	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	22	theme	Bifidobacterium	1183:1197	arg1	species					1199:1205	Lactobacillus and Bifidobacterium species	1165:1205	species	1199:1205	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	4	23	from	inulin	472:477	arg1	composition					490:500	biofilm composition	482:500	biofilm composition	482:500	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	1	24	theme	biofilm	117:123	arg1	composition					125:135	dysbiotic dental biofilm composition	100:135	dysbiotic dental biofilm composition	100:135	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	13	25	theme	bacteria	1711:1718	arg1	effects					1690:1696	the effects	1686:1696	the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity	1686:1810	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	15	26	theme	Additional	1977:1986	arg1	research					1988:1995	Additional research	1977:1995	Additional research	1977:1995	Additional research further elucidating biologic rationale and controlled clinical research defining therapeutic benefits is warranted.					
36542391	14	27	from	study	1884:1888	arg1	results					1859:1865	results	1859:1865	results from the present study	1859:1888	Within the limitations imposed by this model, results from the present study underscore the potential for prebiotic inulin to modify biofilm composition favorably.					
36542391	14	28	theme	present	1876:1882	arg1	study					1884:1888	the present study	1872:1888	the present study	1872:1888	Within the limitations imposed by this model, results from the present study underscore the potential for prebiotic inulin to modify biofilm composition favorably.					
36542391	1	29	theme	ex	137:138	arg1	inulin					90:95	prebiotic inulin	80:95	prebiotic inulin on dysbiotic dental biofilm composition ex vivo	80:143	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	8	30	theme	Diversity	930:938	arg1	metrics					940:946	Diversity metrics	930:946	Diversity metrics of microbial communities	930:971	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	13	31	theme	oligosaccharides	1731:1746	arg1	effects					1690:1696	the effects	1686:1696	the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity	1686:1810	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	5	32	used	used	623:626	arg2	specimens					561:569	METHODS Subgingival plaque specimens	534:569	METHODS Subgingival plaque specimens from three periodontitis-affected human donors	534:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	33	dep	Bifidobacterium	765:779	arg1	animalis					781:788	animalis	781:788	animalis	781:788	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	3	34	dep	Bifidobacterium	390:404	arg1	animalis					406:413	animalis	406:413	animalis	406:413	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	13	35	from	effects	1690:1696	arg1	composition					1785:1795	biofilm composition	1777:1795	biofilm composition	1777:1795	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	13	35	from	effects	1690:1696	arg1	complexity					1801:1810	complexity	1801:1810	complexity	1801:1810	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	9	36	theme	concomitant	1224:1234	arg1	decreases					1236:1244	concomitant decreases	1224:1244	concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1224:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	5	37	theme	hydroxyapatite	648:661	arg1	disks					663:667	hydroxyapatite disks	648:667	hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp	648:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	38	from	disks	663:667	arg1	media					672:676	media	672:676	media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp	672:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	8	39	theme	communities	961:971	arg1	metrics					940:946	Diversity metrics	930:946	Diversity metrics of microbial communities	930:971	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	9	40	from	decreases	1236:1244	arg1	abundances					1258:1267	relative abundances	1249:1267	relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1249:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	5	41	dep	Lactobacillus	738:750	arg1	reuteri					752:758	reuteri	752:758	reuteri	752:758	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	4	42	theme	ex	511:512	arg1	model					527:531	an ex vivo biofilm model	508:531	an ex vivo biofilm model	508:531	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	15	43	theme	clinical	2051:2058	arg1	research					2060:2067	controlled clinical research	2040:2067	controlled clinical research	2040:2067	Additional research further elucidating biologic rationale and controlled clinical research defining therapeutic benefits is warranted.					
36542391	3	44	theme	subsp	415:419	arg1	influence					352:360	the influence	348:360	the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp	348:419	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	4	45	theme	biofilm	519:525	arg1	model					527:531	an ex vivo biofilm model	508:531	an ex vivo biofilm model	508:531	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	11	46	theme	probiotic	1478:1486	arg1	genera					1488:1493	only the supplemented probiotic genera	1456:1493	only the supplemented probiotic genera (p < 0.05)	1456:1504	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	11	46	theme	probiotic	1478:1486	arg1	p < 0.05					1496:1503	p < 0.05	1496:1503	p < 0.05	1496:1503	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	7	47	theme	16S	893:895	arg1	sequencing					918:927	16S rRNA next-generation sequencing	893:927	16S rRNA next-generation sequencing	893:927	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	8	48	theme	microbiome	1012:1021	arg1	platform					1038:1045	a next-generation microbiome bioinformatics platform	994:1045	a next-generation microbiome bioinformatics platform	994:1045	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	3	49	theme	Bifidobacterium	390:404	arg1	subsp					415:419	Lactobacillus reuteri or Bifidobacterium animalis subsp	365:419	Lactobacillus reuteri or Bifidobacterium animalis subsp	365:419	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	9	50	theme	Veillonella	1287:1297	arg1	species					1342:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species	1272:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1272:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	50	theme	Veillonella	1287:1297	arg1	p < 0.001					1351:1359	p < 0.001	1351:1359	p < 0.001	1351:1359	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	1	51	theme	dysbiotic	100:108	arg1	composition					125:135	dysbiotic dental biofilm composition	100:135	dysbiotic dental biofilm composition	100:135	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	12	52	from	decrease	1562:1569	arg1	diversity					1588:1596	biofilm alpha diversity	1574:1596	biofilm alpha diversity (p < 0.001)	1574:1608	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	12	52	from	decrease	1562:1569	arg1	p < 0.001					1599:1607	p < 0.001	1599:1607	p < 0.001	1599:1607	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	9	53	theme	Fusobacterium	1300:1312	arg1	species					1342:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species	1272:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1272:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	53	theme	Fusobacterium	1300:1312	arg1	p < 0.001					1351:1359	p < 0.001	1351:1359	p < 0.001	1351:1359	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	10	54	dep	B.	1394:1395	arg1	animalis					1397:1404	animalis	1397:1404	animalis	1397:1404	Inoculation with L. reuteri or B. animalis subsp.					
36542391	11	55	theme	relative	1434:1441	arg1	abundance					1443:1451	the relative abundance	1430:1451	the relative abundance of only the supplemented probiotic genera (p < 0.05)	1430:1504	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	2	56	theme	bacterial	167:175	arg1	supplementation					177:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	9	57	theme	Parvimonas	1315:1324	arg1	species					1342:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species	1272:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1272:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	57	theme	Parvimonas	1315:1324	arg1	p < 0.001					1351:1359	p < 0.001	1351:1359	p < 0.001	1351:1359	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	13	58	theme	described	1627:1635	arg1	model					1645:1649	The described ex vivo model	1623:1649	The described ex vivo model	1623:1649	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	0	59	theme	animalis	52:59	arg1	Influence					0:8	Influence	0:8	Influence of Lactobacillus reuteri	0:33	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	0	59	theme	animalis	52:59	arg1	subsp					61:65	Bifidobacterium animalis subsp	36:65	Bifidobacterium animalis subsp	36:65	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	7	60	attach	present	845:851	arg1	biofilms					863:870	mature biofilms	856:870	mature biofilms	856:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	7	60	attach	present	845:851	arg2	genera					838:843	bacterial genera	828:843	bacterial genera present in mature biofilms	828:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	7	61	theme	genera	838:843	arg1	abundances					814:823	Relative abundances	805:823	Relative abundances of bacterial genera present in mature biofilms	805:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	2	62	theme	promising	203:211	arg1	results					213:219	promising results	203:219	promising results	203:219	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	9	63	theme	species	1342:1348	arg1	abundances					1258:1267	relative abundances	1249:1267	relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1249:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	1	64	from	inulin	90:95	arg1	composition					125:135	dysbiotic dental biofilm composition	100:135	dysbiotic dental biofilm composition	100:135	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	9	65	theme	Inulin	1056:1061	arg1	supplementation					1063:1077	RESULTS Inulin supplementation	1048:1077	RESULTS Inulin supplementation	1048:1077	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	7	66	theme	Relative	805:812	arg1	abundances					814:823	Relative abundances	805:823	Relative abundances of bacterial genera present in mature biofilms	805:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	15	67	theme	therapeutic	2078:2088	arg1	benefits					2090:2097	therapeutic benefits	2078:2097	therapeutic benefits	2078:2097	Additional research further elucidating biologic rationale and controlled clinical research defining therapeutic benefits is warranted.					
36542391	5	68	theme	inulin	730:735	arg1	combinations					704:715	varying combinations	696:715	varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp	696:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	1	69	from	lactis	68:73	arg1	composition					125:135	dysbiotic dental biofilm composition	100:135	dysbiotic dental biofilm composition	100:135	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	12	70	theme	alpha	1582:1586	arg1	diversity					1588:1596	biofilm alpha diversity	1574:1596	biofilm alpha diversity (p < 0.001)	1574:1608	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	12	70	theme	alpha	1582:1586	arg1	p < 0.001					1599:1607	p < 0.001	1599:1607	p < 0.001	1599:1607	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	9	71	theme	significant	1102:1112	arg1	increases					1129:1137	statistically significant dose-dependent increases	1088:1137	statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001)	1088:1217	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	2	72	theme	BACKGROUND	146:155	arg1	supplementation					177:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation	146:191	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	5	73	theme	METHODS	534:540	arg1	specimens					561:569	METHODS Subgingival plaque specimens	534:569	METHODS Subgingival plaque specimens from three periodontitis-affected human donors	534:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	13	74	dep	ex	1637:1638	arg1	vivo					1640:1643	vivo	1640:1643	vivo	1640:1643	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	5	75	theme	varying	696:702	arg1	combinations					704:715	varying combinations	696:715	varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp	696:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	76	theme	plaque	554:559	arg1	specimens					561:569	METHODS Subgingival plaque specimens	534:569	METHODS Subgingival plaque specimens from three periodontitis-affected human donors	534:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	12	77	theme	significant	1550:1560	arg1	decrease					1562:1569	a statistically significant decrease	1534:1569	a statistically significant decrease in biofilm alpha diversity (p < 0.001)	1534:1608	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	9	78	theme	relative	1142:1149	arg1	abundances					1151:1160	relative abundances	1142:1160	relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001)	1142:1217	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	5	79	theme	Bifidobacterium	765:779	arg1	inulin					730:735	prebiotic inulin	720:735	prebiotic inulin	720:735	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	79	theme	Bifidobacterium	765:779	arg1	subsp					790:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	80	theme	Lactobacillus	738:750	arg1	inulin					730:735	prebiotic inulin	720:735	prebiotic inulin	720:735	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	5	80	theme	Lactobacillus	738:750	arg1	subsp					790:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	Lactobacillus reuteri, and Bifidobacterium animalis subsp	738:794	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	13	81	theme	combinations	1753:1764	arg1	effects					1690:1696	the effects	1686:1696	the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity	1686:1810	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	1	82	theme	dental	110:115	arg1	composition					125:135	dysbiotic dental biofilm composition	100:135	dysbiotic dental biofilm composition	100:135	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	4	83	theme	prebiotic	462:470	arg1	inulin					472:477	prebiotic inulin	462:477	prebiotic inulin on biofilm composition	462:500	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	9	84	theme	species	1199:1205	arg1	abundances					1151:1160	relative abundances	1142:1160	relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001)	1142:1217	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	2	85	theme	periodontal	278:288	arg1	health					290:295	periodontal health	278:295	periodontal health	278:295	BACKGROUND Probiotic bacterial supplementation has shown promising results in the treatment of periodontitis and the maintenance of periodontal health.					
36542391	7	86	from	present	845:851	arg1	biofilms					863:870	mature biofilms	856:870	mature biofilms	856:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	13	87	theme	prebiotic	1721:1729	arg1	oligosaccharides					1731:1746	prebiotic oligosaccharides	1721:1746	prebiotic oligosaccharides	1721:1746	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	12	88	theme	Supplemental	1507:1518	arg1	inulin					1520:1525	Supplemental inulin	1507:1525	Supplemental inulin	1507:1525	Supplemental inulin led to a statistically significant decrease in biofilm alpha diversity (p < 0.001).					
36542391	5	89	theme	periodontitis-affected	582:603	arg1	donors					611:616	three periodontitis-affected human donors	576:616	three periodontitis-affected human donors	576:616	METHODS Subgingival plaque specimens from three periodontitis-affected human donors were used to grow biofilms on hydroxyapatite disks in media supplemented with varying combinations of prebiotic inulin, Lactobacillus reuteri, and Bifidobacterium animalis subsp.					
36542391	11	90	theme	supplemented	1465:1476	arg1	genera					1488:1493	only the supplemented probiotic genera	1456:1493	only the supplemented probiotic genera (p < 0.05)	1456:1504	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	11	90	theme	supplemented	1465:1476	arg1	p < 0.05					1496:1503	p < 0.05	1496:1503	p < 0.05	1496:1503	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	8	91	theme	microbial	951:959	arg1	communities					961:971	microbial communities	951:971	microbial communities	951:971	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	1	92	dep	ex	137:138	arg1	vivo					140:143	vivo	140:143	vivo	140:143	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	9	93	theme	relative	1249:1256	arg1	abundances					1258:1267	relative abundances	1249:1267	relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1249:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	15	94	theme	controlled	2040:2049	arg1	research					2060:2067	controlled clinical research	2040:2067	controlled clinical research	2040:2067	Additional research further elucidating biologic rationale and controlled clinical research defining therapeutic benefits is warranted.					
36542391	3	95	theme	Lactobacillus	365:377	arg1	subsp					415:419	Lactobacillus reuteri or Bifidobacterium animalis subsp	365:419	Lactobacillus reuteri or Bifidobacterium animalis subsp	365:419	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	9	96	from	increases	1129:1137	arg1	abundances					1151:1160	relative abundances	1142:1160	relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001)	1142:1217	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	10	97	with	Inoculation	1363:1373	arg1	subsp					1406:1410	L. reuteri or B. animalis subsp	1380:1410	L. reuteri or B. animalis subsp	1380:1410	Inoculation with L. reuteri or B. animalis subsp.					
36542391	1	98	theme	prebiotic	80:88	arg1	inulin					90:95	prebiotic inulin	80:95	prebiotic inulin on dysbiotic dental biofilm composition ex vivo	80:143	lactis, and prebiotic inulin on dysbiotic dental biofilm composition ex vivo.					
36542391	11	99	theme	genera	1488:1493	arg1	abundance					1443:1451	the relative abundance	1430:1451	the relative abundance of only the supplemented probiotic genera (p < 0.05)	1430:1504	lactis increased the relative abundance of only the supplemented probiotic genera (p < 0.05).					
36542391	13	100	theme	probiotic	1701:1709	arg1	bacteria					1711:1718	probiotic bacteria	1701:1718	probiotic bacteria	1701:1718	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	0	101	theme	reuteri	27:33	arg1	Influence					0:8	Influence	0:8	Influence of Lactobacillus reuteri	0:33	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	0	101	theme	reuteri	27:33	arg1	subsp					61:65	Bifidobacterium animalis subsp	36:65	Bifidobacterium animalis subsp	36:65	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	7	102	theme	rRNA	897:900	arg1	sequencing					918:927	16S rRNA next-generation sequencing	893:927	16S rRNA next-generation sequencing	893:927	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	8	103	theme	next-generation	996:1010	arg1	platform					1038:1045	a next-generation microbiome bioinformatics platform	994:1045	a next-generation microbiome bioinformatics platform	994:1045	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	0	104	theme	Bifidobacterium	36:50	arg1	Influence					0:8	Influence	0:8	Influence of Lactobacillus reuteri	0:33	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	0	104	theme	Bifidobacterium	36:50	arg1	subsp					61:65	Bifidobacterium animalis subsp	36:65	Bifidobacterium animalis subsp	36:65	Influence of Lactobacillus reuteri, Bifidobacterium animalis subsp.					
36542391	4	105	dep	ex	511:512	arg1	vivo					514:517	vivo	514:517	vivo	514:517	lactis supplementation with and without prebiotic inulin on biofilm composition using an ex vivo biofilm model.					
36542391	10	106	dep	L.	1380:1381	arg1	reuteri					1383:1389	reuteri	1383:1389	reuteri	1383:1389	Inoculation with L. reuteri or B. animalis subsp.					
36542391	8	107	theme	bioinformatics	1023:1036	arg1	platform					1038:1045	a next-generation microbiome bioinformatics platform	994:1045	a next-generation microbiome bioinformatics platform	994:1045	Diversity metrics of microbial communities were evaluated using a next-generation microbiome bioinformatics platform.					
36542391	3	108	dep	Lactobacillus	365:377	arg1	reuteri					379:385	reuteri	379:385	reuteri	379:385	The purpose of this investigation was to evaluate the influence of Lactobacillus reuteri or Bifidobacterium animalis subsp.					
36542391	13	109	theme	ex	1637:1638	arg1	model					1645:1649	The described ex vivo model	1623:1649	The described ex vivo model	1623:1649	CONCLUSIONS The described ex vivo model appears suitable for investigating the effects of probiotic bacteria, prebiotic oligosaccharides, and combinations thereof on biofilm composition and complexity.					
36542391	7	110	theme	mature	856:861	arg1	biofilms					863:870	mature biofilms	856:870	mature biofilms	856:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	9	111	theme	Prevotella	1331:1340	arg1	species					1342:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species	1272:1348	Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001)	1272:1360	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	9	111	theme	Prevotella	1331:1340	arg1	p < 0.001					1351:1359	p < 0.001	1351:1359	p < 0.001	1351:1359	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	7	112	theme	present	845:851	arg1	genera					838:843	bacterial genera	828:843	bacterial genera present in mature biofilms	828:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
36542391	9	113	theme	RESULTS	1048:1054	arg1	supplementation					1063:1077	RESULTS Inulin supplementation	1048:1077	RESULTS Inulin supplementation	1048:1077	RESULTS Inulin supplementation produced statistically significant dose-dependent increases in relative abundances of Lactobacillus and Bifidobacterium species (p < 0.001) with concomitant decreases in relative abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species (p < 0.001).					
36542391	7	114	theme	bacterial	828:836	arg1	genera					838:843	bacterial genera	828:843	bacterial genera present in mature biofilms	828:870	Relative abundances of bacterial genera present in mature biofilms were evaluated using 16S rRNA next-generation sequencing.					
35513099	0	0	theme	extracts	92:99	arg1	properties					31:40	multifunctional properties	15:40	multifunctional properties of garlic skin derived cellulose nanocrystals and extracts	15:99	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	6	1	theme	CNCs	855:858	arg1	combination					836:846	The combination	832:846	The combination of the CNCs and GE, on the other hand,	832:885	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	9	2	theme	composite	1237:1245	arg1	films					1247:1251	the chitosan composite films	1224:1251	the chitosan composite films	1224:1251	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	1	3	theme	many	180:183	arg1	years					185:189	many years	180:189	many years	180:189	For many years, garlic has been used as a condiment in food and traditional medicine.					
35513099	5	4	theme	tensile	718:724	arg1	strength					726:733	the films' tensile strength	707:733	the films' tensile strength	707:733	The chitosan-containing films and CNCs have significantly improved the films' tensile strength, Young's modulus, and elongation but decreased the film transparency compared to chitosan films.					
35513099	9	5	theme	degradability	1202:1214	arg1	higher					1269:1274	higher	1269:1274	higher	1269:1274	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	9	5	theme	degradability	1202:1214	arg1	rate					1216:1219	The degradability rate	1198:1219	The degradability rate of the chitosan composite films	1198:1251	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	7	6	theme	UV	1046:1047	arg1	properties					1057:1066	the UV barrier properties	1042:1066	the UV barrier properties	1042:1066	The addition of CNCs slightly decreased the film transparency, while the addition of GE significantly improved the UV barrier properties.					
35513099	3	7	from	skin	446:449	arg1	CNCs					404:407	CNCs	404:407	CNCs	404:407	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	7	from	skin	446:449	arg1	fillers					477:483	fillers	477:483	fillers	477:483	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	7	from	skin	446:449	arg1	nanocrystals					390:401	cellulose nanocrystals	380:401	cellulose nanocrystals (CNCs)	380:408	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	7	from	skin	446:449	arg1	extract					421:427	garlic extract	414:427	garlic extract (GE) from garlic skin	414:449	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	7	from	skin	446:449	arg1	GE					430:431	GE	430:431	GE	430:431	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	2	8	theme	bulk	325:328	arg1	%					309:309	25%	307:309	25% of the garlic bulk	307:328	However, the garlic skin, which accounts for 25% of the garlic bulk, is considered agricultural waste.					
35513099	2	8	theme	bulk	325:328	arg1	bulk					325:328	the garlic bulk	314:328	the garlic bulk	314:328	However, the garlic skin, which accounts for 25% of the garlic bulk, is considered agricultural waste.					
35513099	6	9	theme	mechanical	908:917	arg1	properties					919:928	the mechanical properties	904:928	the mechanical properties	904:928	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	0	10	theme	chitosan	114:121	arg1	films					136:140	chitosan biocomposite films	114:140	chitosan biocomposite films for active packaging application	114:173	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	10	11	theme	films	1346:1350	arg1	properties					1332:1341	The antimicrobial properties	1314:1341	The antimicrobial properties of films	1314:1350	The antimicrobial properties of films were studied against Escherichia coli, Streptomyces griseorubens, Streptomyces alboviridis, and Staphylococcus aureus, observing that their growth was considerably inhibited by the addition of GE in composite films.					
35513099	11	12	theme	due	1679:1681	arg1	applications					1666:1677	active food packaging applications	1644:1677	active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity	1644:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	11	13	theme	active	1644:1649	arg1	applications					1666:1677	active food packaging applications	1644:1677	active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity	1644:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	6	14	dep	CNCs	855:858	arg1	the					851:853	the	851:853	the	851:853	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	4	15	theme	activity	630:637	arg1	terms					552:556	terms	552:556	terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity	552:637	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	9	16	theme	neat	1293:1296	arg1	films					1307:1311	the neat chitosan films	1289:1311	the neat chitosan films	1289:1311	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	2	17	theme	garlic	275:280	arg1	skin					282:285	the garlic skin	271:285	the garlic skin	271:285	However, the garlic skin, which accounts for 25% of the garlic bulk, is considered agricultural waste.					
35513099	11	18	theme	enhanced	1703:1710	arg1	characteristics					1721:1735	enhanced physical characteristics	1703:1735	enhanced physical characteristics	1703:1735	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	0	19	theme	biocomposite	123:134	arg1	films					136:140	chitosan biocomposite films	114:140	chitosan biocomposite films for active packaging application	114:173	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	9	20	theme	chitosan	1228:1235	arg1	films					1247:1251	the chitosan composite films	1224:1251	the chitosan composite films	1224:1251	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	7	21	theme	GE	1016:1017	arg1	addition					1004:1011	the addition	1000:1011	the addition of GE	1000:1017	The addition of CNCs slightly decreased the film transparency, while the addition of GE significantly improved the UV barrier properties.					
35513099	0	22	link	derived	57:63	arg1	nanocrystals					75:86	garlic skin derived cellulose nanocrystals	45:86	garlic skin derived cellulose nanocrystals	45:86	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	3	23	used	used	469:472	arg2	nanocrystals					390:401	cellulose nanocrystals	380:401	cellulose nanocrystals (CNCs)	380:408	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	23	used	used	469:472	arg2	fillers					477:483	fillers	477:483	fillers	477:483	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	23	used	used	469:472	arg2	CNCs					404:407	CNCs	404:407	CNCs	404:407	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	6	24	from	CNCs	855:858	arg1	hand					881:884	the other hand	871:884	the other hand	871:884	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	11	25	theme	physical	1712:1719	arg1	characteristics					1721:1735	enhanced physical characteristics	1703:1735	enhanced physical characteristics	1703:1735	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	8	26	theme	thermal	1157:1163	arg1	stability					1165:1173	the thermal stability	1153:1173	the thermal stability of the chitosan films	1153:1195	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	6	27	from	GE	864:865	arg1	hand					881:884	the other hand	871:884	the other hand	871:884	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	9	28	theme	films	1247:1251	arg1	higher					1269:1274	higher	1269:1274	higher	1269:1274	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	9	28	theme	films	1247:1251	arg1	rate					1216:1219	The degradability rate	1198:1219	The degradability rate of the chitosan composite films	1198:1251	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	11	29	theme	antibacterial	1741:1753	arg1	activity					1755:1762	antibacterial activity	1741:1762	antibacterial activity	1741:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	8	30	theme	Thermal	1069:1075	arg1	studies					1077:1083	Thermal studies	1069:1083	Thermal studies	1069:1083	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	2	31	theme	agricultural	345:356	arg1	waste					358:362	agricultural waste	345:362	agricultural waste	345:362	However, the garlic skin, which accounts for 25% of the garlic bulk, is considered agricultural waste.					
35513099	0	32	theme	properties	31:40	arg1	Exploration					0:10	Exploration	0:10	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts	0:99	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	11	33	theme	characteristics	1721:1735	arg1	combination					1688:1698	a combination	1686:1698	a combination of enhanced physical characteristics and antibacterial activity	1686:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	0	34	theme	active	146:151	arg1	application					163:173	active packaging application	146:173	active packaging application	146:173	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	8	35	contain	had	1131:1133	arg2	effect					1143:1148	minimal effect	1135:1148	minimal effect	1135:1148	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	8	35	contain	had	1131:1133	arg1	incorporation					1103:1115	the incorporation	1099:1115	the incorporation of CNC and GE	1099:1129	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	5	36	theme	Young	736:740	arg1	modulus					744:750	Young's modulus	736:750	Young's modulus	736:750	The chitosan-containing films and CNCs have significantly improved the films' tensile strength, Young's modulus, and elongation but decreased the film transparency compared to chitosan films.					
35513099	0	37	theme	multifunctional	15:29	arg1	properties					31:40	multifunctional properties	15:40	multifunctional properties of garlic skin derived cellulose nanocrystals and extracts	15:99	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	5	38	theme	chitosan-containing	644:662	arg1	films					664:668	The chitosan-containing films	640:668	The chitosan-containing films	640:668	The chitosan-containing films and CNCs have significantly improved the films' tensile strength, Young's modulus, and elongation but decreased the film transparency compared to chitosan films.					
35513099	11	39	theme	garlic	1610:1615	arg1	skin					1617:1620	garlic skin	1610:1620	garlic skin	1610:1620	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	3	40	theme	biocomposite	500:511	arg1	films					513:517	biocomposite films	500:517	biocomposite films	500:517	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	4	41	theme	barrier	564:570	arg1	terms					552:556	terms	552:556	terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity	552:637	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	0	42	theme	garlic	45:50	arg1	nanocrystals					75:86	garlic skin derived cellulose nanocrystals	45:86	garlic skin derived cellulose nanocrystals	45:86	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	6	43	theme	other	875:879	arg1	hand					881:884	the other hand	871:884	the other hand	871:884	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	7	44	theme	film	975:978	arg1	transparency					980:991	the film transparency	971:991	the film transparency	971:991	The addition of CNCs slightly decreased the film transparency, while the addition of GE significantly improved the UV barrier properties.					
35513099	8	45	theme	films	1191:1195	arg1	stability					1165:1173	the thermal stability	1153:1173	the thermal stability of the chitosan films	1153:1195	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	0	46	dep	derived	57:63	arg1	skin					52:55	skin	52:55	skin	52:55	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	4	47	theme	biodegradability	594:609	arg1	terms					552:556	terms	552:556	terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity	552:637	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	7	48	theme	barrier	1049:1055	arg1	properties					1057:1066	the UV barrier properties	1042:1066	the UV barrier properties	1042:1066	The addition of CNCs slightly decreased the film transparency, while the addition of GE significantly improved the UV barrier properties.					
35513099	3	49	theme	cellulose	380:388	arg1	CNCs					404:407	CNCs	404:407	CNCs	404:407	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	49	theme	cellulose	380:388	arg1	fillers					477:483	fillers	477:483	fillers	477:483	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	49	theme	cellulose	380:388	arg1	nanocrystals					390:401	cellulose nanocrystals	380:401	cellulose nanocrystals (CNCs)	380:408	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	11	50	theme	activity	1755:1762	arg1	combination					1688:1698	a combination	1686:1698	a combination of enhanced physical characteristics and antibacterial activity	1686:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	0	51	theme	packaging	153:161	arg1	application					163:173	active packaging application	146:173	active packaging application	146:173	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	4	52	dep	thermal	573:579	arg1	mechanical					582:591	mechanical	582:591	mechanical	582:591	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	5	53	theme	film	786:789	arg1	transparency					791:802	the film transparency	782:802	the film transparency	782:802	The chitosan-containing films and CNCs have significantly improved the films' tensile strength, Young's modulus, and elongation but decreased the film transparency compared to chitosan films.					
35513099	3	54	theme	garlic	414:419	arg1	GE					430:431	GE	430:431	GE	430:431	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	3	54	theme	garlic	414:419	arg1	extract					421:427	garlic extract	414:427	garlic extract (GE) from garlic skin	414:449	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	0	55	theme	derived	57:63	arg1	nanocrystals					75:86	garlic skin derived cellulose nanocrystals	45:86	garlic skin derived cellulose nanocrystals	45:86	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	10	56	theme	composite	1551:1559	arg1	films					1561:1565	composite films	1551:1565	composite films	1551:1565	The antimicrobial properties of films were studied against Escherichia coli, Streptomyces griseorubens, Streptomyces alboviridis, and Staphylococcus aureus, observing that their growth was considerably inhibited by the addition of GE in composite films.					
35513099	8	57	theme	GE	1128:1129	arg1	incorporation					1103:1115	the incorporation	1099:1115	the incorporation of CNC and GE	1099:1129	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	1	58	from	condiment	218:226	arg1	food					231:234	food	231:234	food	231:234	For many years, garlic has been used as a condiment in food and traditional medicine.					
35513099	1	58	from	condiment	218:226	arg1	medicine					252:259	traditional medicine	240:259	traditional medicine	240:259	For many years, garlic has been used as a condiment in food and traditional medicine.					
35513099	2	59	theme	garlic	318:323	arg1	bulk					325:328	the garlic bulk	314:328	the garlic bulk	314:328	However, the garlic skin, which accounts for 25% of the garlic bulk, is considered agricultural waste.					
35513099	8	60	theme	minimal	1135:1141	arg1	effect					1143:1148	minimal effect	1135:1148	minimal effect	1135:1148	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	6	61	from	hand	881:884	arg1	combination					836:846	The combination	832:846	The combination of the CNCs and GE, on the other hand,	832:885	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	1	62	used	used	208:211	arg2	condiment					218:226	a condiment	216:226	a condiment in food and traditional medicine	216:259	For many years, garlic has been used as a condiment in food and traditional medicine.					
35513099	1	62	used	used	208:211	arg2	garlic					192:197	garlic	192:197	garlic	192:197	For many years, garlic has been used as a condiment in food and traditional medicine.					
35513099	3	63	theme	garlic	439:444	arg1	skin					446:449	garlic skin	439:449	garlic skin	439:449	In this study, cellulose nanocrystals (CNCs) and garlic extract (GE) from garlic skin were isolated and used as fillers to manufacture biocomposite films.					
35513099	6	64	theme	GE	864:865	arg1	combination					836:846	The combination	832:846	The combination of the CNCs and GE, on the other hand,	832:885	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	7	65	theme	CNCs	947:950	arg1	addition					935:942	The addition	931:942	The addition of CNCs	931:950	The addition of CNCs slightly decreased the film transparency, while the addition of GE significantly improved the UV barrier properties.					
35513099	10	66	theme	antimicrobial	1318:1330	arg1	properties					1332:1341	The antimicrobial properties	1314:1341	The antimicrobial properties of films	1314:1350	The antimicrobial properties of films were studied against Escherichia coli, Streptomyces griseorubens, Streptomyces alboviridis, and Staphylococcus aureus, observing that their growth was considerably inhibited by the addition of GE in composite films.					
35513099	6	67	from	combination	836:846	arg1	hand					881:884	the other hand	871:884	the other hand	871:884	The combination of the CNCs and GE, on the other hand, slightly reduced the mechanical properties.					
35513099	5	68	theme	chitosan	816:823	arg1	films					825:829	chitosan films	816:829	chitosan films	816:829	The chitosan-containing films and CNCs have significantly improved the films' tensile strength, Young's modulus, and elongation but decreased the film transparency compared to chitosan films.					
35513099	8	69	theme	chitosan	1182:1189	arg1	films					1191:1195	the chitosan films	1178:1195	the chitosan films	1178:1195	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	11	70	theme	food	1651:1654	arg1	applications					1666:1677	active food packaging applications	1644:1677	active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity	1644:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	10	71	theme	GE	1545:1546	arg1	addition					1533:1540	the addition	1529:1540	the addition of GE in composite films	1529:1565	The antimicrobial properties of films were studied against Escherichia coli, Streptomyces griseorubens, Streptomyces alboviridis, and Staphylococcus aureus, observing that their growth was considerably inhibited by the addition of GE in composite films.					
35513099	0	72	theme	nanocrystals	75:86	arg1	properties					31:40	multifunctional properties	15:40	multifunctional properties of garlic skin derived cellulose nanocrystals and extracts	15:99	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	4	73	theme	thermal	573:579	arg1	barrier					564:570	UV barrier	561:570	UV barrier	561:570	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	4	74	theme	antimicrobial	616:628	arg1	activity					630:637	antimicrobial activity	616:637	antimicrobial activity	616:637	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	10	75	from	addition	1533:1540	arg1	films					1561:1565	composite films	1551:1565	composite films	1551:1565	The antimicrobial properties of films were studied against Escherichia coli, Streptomyces griseorubens, Streptomyces alboviridis, and Staphylococcus aureus, observing that their growth was considerably inhibited by the addition of GE in composite films.					
35513099	4	76	theme	UV	561:562	arg1	barrier					564:570	UV barrier	561:570	UV barrier	561:570	The films were characterized in terms of UV barrier, thermal, mechanical, biodegradability, and antimicrobial activity.					
35513099	0	77	theme	cellulose	65:73	arg1	nanocrystals					75:86	garlic skin derived cellulose nanocrystals	45:86	garlic skin derived cellulose nanocrystals	45:86	Exploration of multifunctional properties of garlic skin derived cellulose nanocrystals and extracts incorporated chitosan biocomposite films for active packaging application.					
35513099	8	78	theme	CNC	1120:1122	arg1	incorporation					1103:1115	the incorporation	1099:1115	the incorporation of CNC and GE	1099:1129	Thermal studies revealed that the incorporation of CNC and GE had minimal effect on the thermal stability of the chitosan films.					
35513099	11	79	theme	packaging	1656:1664	arg1	applications					1666:1677	active food packaging applications	1644:1677	active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity	1644:1762	Films incorporating both CNCs and GE from garlic skin hold more promise for active food packaging applications due to a combination of enhanced physical characteristics and antibacterial activity.					
35513099	9	80	theme	chitosan	1298:1305	arg1	films					1307:1311	the neat chitosan films	1289:1311	the neat chitosan films	1289:1311	The degradability rate of the chitosan composite films was found to be higher than that of the neat chitosan films.					
35513099	1	81	theme	traditional	240:250	arg1	medicine					252:259	traditional medicine	240:259	traditional medicine	240:259	For many years, garlic has been used as a condiment in food and traditional medicine.					
35522599	7	0	from	conditions	1439:1448	arg1	proliferation					1333:1345	the cellular proliferation	1320:1345	the cellular proliferation on the 10:1 matrix	1320:1364	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	7	0	from	conditions	1439:1448	arg1	similar					1382:1388	similar	1382:1388	similar	1382:1388	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	8	1	theme	tissue	1778:1783	arg1	regeneration					1785:1796	tissue regeneration	1778:1796	tissue regeneration	1778:1796	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	2	2	theme	native	346:351	arg1	ECM					375:377	ECM	375:377	ECM	375:377	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	2	theme	native	346:351	arg1	matrix					367:372	the native extracellular matrix	342:372	the native extracellular matrix (ECM)	342:378	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	9	3	theme	assembly	1819:1826	arg1	approach					1828:1835	This multicomponent assembly approach	1799:1835	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold	1799:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	6	4	theme	cell	1275:1278	arg1	conditions					1288:1297	two-dimensional cell culture conditions	1259:1297	two-dimensional cell culture conditions	1259:1297	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	3	5	theme	supramolecular	787:800	arg1	hydrogels					802:810	highly tunable supramolecular hydrogels	772:810	highly tunable supramolecular hydrogels	772:810	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	7	6	theme	advanced	1511:1518	arg1	applications					1539:1550	advanced tissue engineering applications	1511:1550	advanced tissue engineering applications	1511:1550	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	9	7	theme	superior	1893:1900	arg1	properties					1926:1935	access superior physical and biological properties	1886:1935	access superior physical and biological properties within the scaffold	1886:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	2	8	theme	advanced	621:628	arg1	scaffolds					637:645	advanced tissue scaffolds	621:645	advanced tissue scaffolds	621:645	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	7	9	from	similar	1382:1388	arg1	conditions					1439:1448	three-dimensional culture conditions	1413:1448	three-dimensional culture conditions	1413:1448	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	7	10	theme	hydrogels	1498:1506	arg1	potential					1479:1487	the potential	1475:1487	the potential of these hydrogels in advanced tissue engineering applications	1475:1550	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	2	11	theme	matrix	367:372	arg1	nature					332:337	the multicomponent nature	313:337	the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology	313:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	1	12	theme	superior	256:263	arg1	properties					289:298	superior physical and biological properties	256:298	superior physical and biological properties	256:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	8	13	theme	composite	1573:1581	arg1	hydrogels					1583:1591	these composite hydrogels	1567:1591	these composite hydrogels	1567:1591	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	3	14	theme	TEMPO-oxidized	660:673	arg1	TO-NFC					700:705	TO-NFC	700:705	TO-NFC	700:705	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	3	14	theme	TEMPO-oxidized	660:673	arg1	cellulose					689:697	TEMPO-oxidized nanofibrillar cellulose	660:697	TEMPO-oxidized nanofibrillar cellulose (TO-NFC)	660:706	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	5	15	theme	differential	1000:1011	arg1	response					1022:1029	a differential cellular response	998:1029	a differential cellular response	998:1029	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	9	16	theme	physical	1902:1909	arg1	properties					1926:1935	access superior physical and biological properties	1886:1935	access superior physical and biological properties within the scaffold	1886:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	2	17	theme	multicomponent	317:330	arg1	nature					332:337	the multicomponent nature	313:337	the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology	313:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	6	18	theme	Composite	1120:1128	arg1	scaffolds					1130:1138	Composite scaffolds	1120:1138	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC	1120:1174	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	9	19	theme	biological	1915:1924	arg1	properties					1926:1935	access superior physical and biological properties	1886:1935	access superior physical and biological properties within the scaffold	1886:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	0	20	theme	Peptide	83:89	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	20	theme	Peptide	83:89	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	20	theme	Peptide	83:89	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	2	21	theme	biomolecular	555:566	arg1	blocks					577:582	the sugar and peptide-based biomolecular building blocks	527:582	blocks	577:582	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	8	22	theme	significant	1612:1622	arg1	response					1637:1644	any significant inflammatory response	1608:1644	any significant inflammatory response in Raw cells	1608:1657	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	7	23	theme	cellular	1324:1331	arg1	proliferation					1333:1345	the cellular proliferation	1320:1345	the cellular proliferation on the 10:1 matrix	1320:1364	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	7	23	theme	cellular	1324:1331	arg1	similar					1382:1388	similar	1382:1388	similar	1382:1388	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	1	24	theme	peptide	203:209	arg1	nanotechnology					211:224	peptide nanotechnology	203:224	peptide nanotechnology	203:224	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	0	25	theme	Biofunctional	113:125	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	25	theme	Biofunctional	113:125	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	25	theme	Biofunctional	113:125	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	7	26	theme	10:1	1354:1357	arg1	matrix					1359:1364	the 10:1 matrix	1350:1364	the 10:1 matrix	1350:1364	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	8	27	theme	Raw	1649:1651	arg1	cells					1653:1657	Raw cells	1649:1657	Raw cells	1649:1657	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	4	28	theme	TO-NFC	861:866	arg1	hydrogel					868:875	the TO-NFC hydrogel	857:875	the TO-NFC hydrogel	857:875	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	5	29	theme	variable	1078:1085	arg1	ratio					1087:1091	a variable ratio	1076:1091	a variable ratio of TO-NFC versus Nap-FEFK	1076:1117	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	8	30	from	response	1637:1644	arg1	cells					1653:1657	Raw cells	1649:1657	Raw cells	1649:1657	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	7	31	theme	three-dimensional	1413:1429	arg1	conditions					1439:1448	three-dimensional culture conditions	1413:1448	three-dimensional culture conditions	1413:1448	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	0	32	theme	TEMPO-Oxidized	14:27	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	32	theme	TEMPO-Oxidized	14:27	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	32	theme	TEMPO-Oxidized	14:27	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	7	33	theme	engineering	1527:1537	arg1	applications					1539:1550	advanced tissue engineering applications	1511:1550	advanced tissue engineering applications	1511:1550	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	5	34	theme	composite	1051:1059	arg1	scaffolds					1061:1069	composite scaffolds	1051:1069	composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK	1051:1117	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	6	35	theme	10:1	1149:1152	arg1	ratio					1160:1164	a 10:1 (w/w) ratio	1147:1164	a 10:1 (w/w) ratio of TO-NFC	1147:1174	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	3	36	theme	complementary	726:738	arg1	Nap-FEFK					749:756	Nap-FEFK	749:756	Nap-FEFK	749:756	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	3	36	theme	complementary	726:738	arg1	peptide					740:746	a short ionic complementary peptide	712:746	a short ionic complementary peptide	712:746	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	9	37	theme	ECM-mimicking	2010:2022	arg1	biomaterials					2024:2035	novel ECM-mimicking biomaterials	2004:2035	novel ECM-mimicking biomaterials	2004:2035	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	3	38	theme	short	714:718	arg1	Nap-FEFK					749:756	Nap-FEFK	749:756	Nap-FEFK	749:756	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	3	38	theme	short	714:718	arg1	peptide					740:746	a short ionic complementary peptide	712:746	a short ionic complementary peptide	712:746	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	2	39	theme	advantages	405:414	arg1	nature					332:337	the multicomponent nature	313:337	the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology	313:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	0	40	theme	Short	57:61	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	40	theme	Short	57:61	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	40	theme	Short	57:61	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	1	41	with	nanomaterials	237:249	arg1	properties					289:298	superior physical and biological properties	256:298	superior physical and biological properties	256:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	6	42	theme	enhanced	1208:1215	arg1	survival					1226:1233	enhanced cellular survival	1208:1233	enhanced cellular survival	1208:1233	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	1	43	theme	biological	278:287	arg1	properties					289:298	superior physical and biological properties	256:298	superior physical and biological properties	256:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	3	44	theme	tunable	779:785	arg1	hydrogels					802:810	highly tunable supramolecular hydrogels	772:810	highly tunable supramolecular hydrogels	772:810	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	2	45	theme	co-assembly	419:429	arg1	advantages					405:414	the well-established advantages	384:414	the well-established advantages of co-assembly in the field of nanotechnology	384:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	45	theme	co-assembly	419:429	arg1	ECM					375:377	ECM	375:377	ECM	375:377	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	45	theme	co-assembly	419:429	arg1	matrix					367:372	the native extracellular matrix	342:372	the native extracellular matrix (ECM)	342:378	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	4	46	theme	mechanical	945:954	arg1	stiffness					956:964	mechanical stiffness	945:964	mechanical stiffness	945:964	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	6	47	theme	TO-NFC	1169:1174	arg1	ratio					1160:1164	a 10:1 (w/w) ratio	1147:1164	a 10:1 (w/w) ratio of TO-NFC	1147:1174	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	8	48	theme	versatile	1754:1762	arg1	scaffolds					1764:1772	versatile scaffolds	1754:1772	versatile scaffolds for tissue regeneration	1754:1796	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	2	49	theme	extracellular	353:365	arg1	ECM					375:377	ECM	375:377	ECM	375:377	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	49	theme	extracellular	353:365	arg1	matrix					367:372	the native extracellular matrix	342:372	the native extracellular matrix (ECM)	342:378	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	9	50	theme	multicomponent	1804:1817	arg1	approach					1828:1835	This multicomponent assembly approach	1799:1835	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold	1799:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	2	51	from	advantages	405:414	arg1	field					438:442	the field	434:442	the field of nanotechnology	434:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	6	52	theme	culture	1280:1286	arg1	conditions					1288:1297	two-dimensional cell culture conditions	1259:1297	two-dimensional cell culture conditions	1259:1297	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	9	53	dep	approach	1828:1835	arg1	construct					1840:1848	construct	1840:1848	to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold	1837:1955	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	2	54	from	co-assembly	419:429	arg1	field					438:442	the field	434:442	the field of nanotechnology	434:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	6	55	theme	two-dimensional	1259:1273	arg1	conditions					1288:1297	two-dimensional cell culture conditions	1259:1297	two-dimensional cell culture conditions	1259:1297	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	7	56	theme	tissue	1520:1525	arg1	applications					1539:1550	advanced tissue engineering applications	1511:1550	advanced tissue engineering applications	1511:1550	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	9	57	theme	composite	1863:1871	arg1	hydrogels					1873:1881	biomolecular composite hydrogels	1850:1881	biomolecular composite hydrogels	1850:1881	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	3	58	theme	nanofibrillar	675:687	arg1	TO-NFC					700:705	TO-NFC	700:705	TO-NFC	700:705	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	3	58	theme	nanofibrillar	675:687	arg1	cellulose					689:697	TEMPO-oxidized nanofibrillar cellulose	660:697	TEMPO-oxidized nanofibrillar cellulose (TO-NFC)	660:706	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	1	59	theme	physical	265:272	arg1	properties					289:298	superior physical and biological properties	256:298	superior physical and biological properties	256:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	5	60	with	scaffolds	1061:1069	arg1	ratio					1087:1091	a variable ratio	1076:1091	a variable ratio of TO-NFC versus Nap-FEFK	1076:1117	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	1	61	theme	Multicomponent	147:160	arg1	approach					191:198	an emerging approach	179:198	an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties	179:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	1	61	theme	Multicomponent	147:160	arg1	self-assembly					162:174	Multicomponent self-assembly	147:174	Multicomponent self-assembly	147:174	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	4	62	theme	scaffold	973:980	arg1	stiffness					956:964	mechanical stiffness	945:964	mechanical stiffness	945:964	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	4	62	theme	scaffold	973:980	arg1	microporosity					926:938	microporosity	926:938	microporosity	926:938	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	4	62	theme	scaffold	973:980	arg1	hydrophobicity					910:923	the surface hydrophobicity	898:923	the surface hydrophobicity	898:923	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	3	63	used	utilized	651:658	arg2	We					648:649	We	648:649	We	648:649	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	5	64	theme	cellular	1013:1020	arg1	response					1022:1029	a differential cellular response	998:1029	a differential cellular response	998:1029	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	2	65	theme	tissue	630:635	arg1	scaffolds					637:645	advanced tissue scaffolds	621:645	advanced tissue scaffolds	621:645	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	7	66	from	proliferation	1333:1345	arg1	matrix					1359:1364	the 10:1 matrix	1350:1364	the 10:1 matrix	1350:1364	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	0	67	theme	Composite	91:99	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	67	theme	Composite	91:99	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	67	theme	Composite	91:99	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	1	68	theme	emerging	182:189	arg1	approach					191:198	an emerging approach	179:198	an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties	179:298	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	1	68	theme	emerging	182:189	arg1	self-assembly					162:174	Multicomponent self-assembly	147:174	Multicomponent self-assembly	147:174	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	2	69	theme	building	568:575	arg1	blocks					577:582	the sugar and peptide-based biomolecular building blocks	527:582	blocks	577:582	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	8	70	theme	inflammatory	1624:1635	arg1	response					1637:1644	any significant inflammatory response	1608:1644	any significant inflammatory response in Raw cells	1608:1657	Additionally, these composite hydrogels did not elicit any significant inflammatory response in Raw cells and supported their survival and proliferation, which further emphasized their ability to form versatile scaffolds for tissue regeneration.					
35522599	2	71	from	matrix	367:372	arg1	field					438:442	the field	434:442	the field of nanotechnology	434:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	72	theme	peptide-based	541:553	arg1	blocks					577:582	the sugar and peptide-based biomolecular building blocks	527:582	blocks	577:582	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	0	73	theme	Cellular	127:134	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	73	theme	Cellular	127:134	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	73	theme	Cellular	127:134	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	6	74	contain	having	1140:1145	arg2	ratio					1160:1164	a 10:1 (w/w) ratio	1147:1164	a 10:1 (w/w) ratio of TO-NFC	1147:1174	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	6	74	contain	having	1140:1145	arg1	scaffolds					1130:1138	Composite scaffolds	1120:1138	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC	1120:1174	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	4	75	theme	peptide	844:850	arg1	doping					830:835	The differential doping	813:835	The differential doping of the peptide into the TO-NFC hydrogel	813:875	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	1	76	from	approach	191:198	arg1	nanotechnology					211:224	peptide nanotechnology	203:224	peptide nanotechnology	203:224	Multicomponent self-assembly is an emerging approach in peptide nanotechnology to develop nanomaterials with superior physical and biological properties.					
35522599	7	77	theme	culture	1431:1437	arg1	conditions					1439:1448	three-dimensional culture conditions	1413:1448	three-dimensional culture conditions	1413:1448	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	2	78	theme	nanotechnology	447:460	arg1	field					438:442	the field	434:442	the field of nanotechnology	434:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	79	theme	noncovalent	496:506	arg1	interactions					508:519	the noncovalent interactions	492:519	the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design	492:607	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	4	80	theme	differential	817:828	arg1	doping					830:835	The differential doping	813:835	The differential doping of the peptide into the TO-NFC hydrogel	813:875	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	0	81	theme	Nanofibrillar	29:41	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	81	theme	Nanofibrillar	29:41	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	81	theme	Nanofibrillar	29:41	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	7	82	from	potential	1479:1487	arg1	applications					1539:1550	advanced tissue engineering applications	1511:1550	advanced tissue engineering applications	1511:1550	More interestingly, the cellular proliferation on the 10:1 matrix was found to be similar to that of Matrigel in three-dimensional culture conditions, which clearly indicated the potential of these hydrogels in advanced tissue engineering applications.					
35522599	3	83	theme	ionic	720:724	arg1	Nap-FEFK					749:756	Nap-FEFK	749:756	Nap-FEFK	749:756	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	3	83	theme	ionic	720:724	arg1	peptide					740:746	a short ionic complementary peptide	712:746	a short ionic complementary peptide	712:746	We utilized TEMPO-oxidized nanofibrillar cellulose (TO-NFC) and a short ionic complementary peptide, Nap-FEFK, to fabricate highly tunable supramolecular hydrogels.					
35522599	5	84	theme	Nap-FEFK	1110:1117	arg1	ratio					1087:1091	a variable ratio	1076:1091	a variable ratio of TO-NFC versus Nap-FEFK	1076:1117	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	9	85	theme	novel	2004:2008	arg1	biomaterials					2024:2035	novel ECM-mimicking biomaterials	2004:2035	novel ECM-mimicking biomaterials	2004:2035	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	0	86	theme	Ionic-Complementary	63:81	arg1	Hydrogel					101:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Short Ionic-Complementary Peptide Composite Hydrogel	57:108	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	86	theme	Ionic-Complementary	63:81	arg1	Scaffolds					136:144	Biofunctional Cellular Scaffolds	113:144	Biofunctional Cellular Scaffolds	113:144	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	0	86	theme	Ionic-Complementary	63:81	arg1	Cellulose					43:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	the TEMPO-Oxidized Nanofibrillar Cellulose	10:51	Exploring the TEMPO-Oxidized Nanofibrillar Cellulose and Short Ionic-Complementary Peptide Composite Hydrogel as Biofunctional Cellular Scaffolds.					
35522599	2	87	from	field	438:442	arg1	advantages					405:414	the well-established advantages	384:414	the well-established advantages of co-assembly in the field of nanotechnology	384:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	87	from	field	438:442	arg1	ECM					375:377	ECM	375:377	ECM	375:377	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	2	87	from	field	438:442	arg1	matrix					367:372	the native extracellular matrix	342:372	the native extracellular matrix (ECM)	342:378	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	6	88	theme	cellular	1217:1224	arg1	survival					1226:1233	enhanced cellular survival	1208:1233	enhanced cellular survival	1208:1233	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35522599	4	89	theme	surface	902:908	arg1	hydrophobicity					910:923	the surface hydrophobicity	898:923	the surface hydrophobicity	898:923	The differential doping of the peptide into the TO-NFC hydrogel was observed to tune the surface hydrophobicity, microporosity, and mechanical stiffness of the scaffold.					
35522599	2	90	theme	well-established	388:403	arg1	advantages					405:414	the well-established advantages	384:414	the well-established advantages of co-assembly in the field of nanotechnology	384:460	Inspired by the multicomponent nature of the native extracellular matrix (ECM) and the well-established advantages of co-assembly in the field of nanotechnology, we have attempted to explore the noncovalent interactions among the sugar and peptide-based biomolecular building blocks as an approach to design and develop advanced tissue scaffolds.					
35522599	9	91	theme	biomolecular	1850:1861	arg1	hydrogels					1873:1881	biomolecular composite hydrogels	1850:1881	biomolecular composite hydrogels	1850:1881	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	9	92	theme	regenerative	2041:2052	arg1	medicine					2054:2061	regenerative medicine	2041:2061	regenerative medicine	2041:2061	This multicomponent assembly approach to construct biomolecular composite hydrogels to access superior physical and biological properties within the scaffold is expected to improve the scope for designing novel ECM-mimicking biomaterials for regenerative medicine.					
35522599	5	93	theme	TO-NFC	1096:1101	arg1	ratio					1087:1091	a variable ratio	1076:1091	a variable ratio of TO-NFC versus Nap-FEFK	1076:1117	Interestingly, a differential cellular response was observed toward composite scaffolds with a variable ratio of TO-NFC versus Nap-FEFK.					
35522599	6	94	theme	Nap-FEFK	1184:1191	arg1	peptide					1193:1199	the Nap-FEFK peptide	1180:1199	the Nap-FEFK peptide	1180:1199	Composite scaffolds having a 10:1 (w/w) ratio of TO-NFC and the Nap-FEFK peptide showed enhanced cellular survival and proliferation under two-dimensional cell culture conditions.					
35321974	1	0	theme	sustained	156:164	arg1	release					166:172	sustained release	156:172	sustained release of minocycline	156:187	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	0	1	theme	defect	92:97	arg1	repair					99:104	periodontal bone defect repair	75:104	periodontal bone defect repair	75:104	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	0	2	from	release	11:17	arg1	composite					61:69	hydroxyapatite/chitosan composite	37:69	hydroxyapatite/chitosan composite	37:69	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	4	3	theme	material	741:748	arg1	prolonged					754:762	prolonged	754:762	prolonged	754:762	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	4	3	theme	material	741:748	arg1	time					729:732	the setting time	717:732	the setting time of the material	717:748	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	3	4	theme	rabbit	568:573	arg1	model					575:579	the rabbit model	564:579	the rabbit model of mandible bone defect	564:603	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	5	from	effects	623:629	arg1	regeneration					638:649	the regeneration	634:649	the regeneration of periodontal bone defect	634:676	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	5	6	theme	neutral	919:925	arg1	range					927:931	the neutral range	915:931	the neutral range	915:931	The pH value did not change obviously and stayed in the neutral range.					
35321974	4	7	theme	setting	721:727	arg1	prolonged					754:762	prolonged	754:762	prolonged	754:762	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	4	7	theme	setting	721:727	arg1	time					729:732	the setting time	717:732	the setting time of the material	717:748	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	7	8	theme	bone	1102:1105	arg1	formation					1107:1115	periodontal bone formation	1090:1115	periodontal bone formation	1090:1115	In vivo, Mino-HA/CS material showed better effect of promoting periodontal bone formation.					
35321974	6	9	theme	osteoblasts	973:983	arg1	growth					963:968	the growth	959:968	the growth of osteoblasts	959:983	Mino-HA/CS could promote the growth of osteoblasts effectively compared with control medium.					
35321974	4	10	theme	compressive	769:779	arg1	strength					781:788	the compressive strength	765:788	the compressive strength	765:788	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	1	11	theme	minocycline	177:187	arg1	release					166:172	sustained release	156:172	sustained release of minocycline	156:187	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	3	12	theme	physical	406:413	arg1	property					428:435	The physical and chemical property	402:435	The physical and chemical property	402:435	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	13	theme	mandible	584:591	arg1	defect					598:603	mandible bone defect	584:603	mandible bone defect	584:603	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	7	14	theme	periodontal	1090:1100	arg1	formation					1107:1115	periodontal bone formation	1090:1115	periodontal bone formation	1090:1115	In vivo, Mino-HA/CS material showed better effect of promoting periodontal bone formation.					
35321974	3	15	theme	bone	593:596	arg1	defect					598:603	mandible bone defect	584:603	mandible bone defect	584:603	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	0	16	theme	minocycline	22:32	arg1	release					11:17	release	11:17	release of minocycline in hydroxyapatite/chitosan composite	11:69	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	3	17	theme	bacteriostasis	483:496	arg1	examination					498:508	the bacteriostasis examination	479:508	the bacteriostasis examination of the materials	479:525	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	18	theme	bone	666:669	arg1	defect					671:676	periodontal bone defect	654:676	periodontal bone defect	654:676	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	5	19	theme	pH	867:868	arg1	value					870:874	The pH value	863:874	The pH value	863:874	The pH value did not change obviously and stayed in the neutral range.					
35321974	0	20	theme	hydroxyapatite/chitosan	37:59	arg1	composite					61:69	hydroxyapatite/chitosan composite	37:69	hydroxyapatite/chitosan composite	37:69	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	3	21	theme	defect	671:676	arg1	regeneration					638:649	the regeneration	634:649	the regeneration of periodontal bone defect	634:676	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	7	22	theme	better	1063:1068	arg1	effect					1070:1075	better effect	1063:1075	better effect of promoting periodontal bone formation	1063:1115	In vivo, Mino-HA/CS material showed better effect of promoting periodontal bone formation.					
35321974	4	23	theme	pore	810:813	arg1	size					815:818	the pore size	806:818	the pore size	806:818	After minocycline was added to HA/CS, the setting time of the material was prolonged, the compressive strength was reduced and the pore size and porosity were increased significantly.					
35321974	1	24	theme	periodontal	216:226	arg1	repair					240:245	periodontal bone defect repair	216:245	periodontal bone defect repair	216:245	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	3	25	theme	chemical	419:426	arg1	property					428:435	The physical and chemical property	402:435	The physical and chemical property	402:435	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	7	26	theme	Mino-HA/CS	1036:1045	arg1	material					1047:1054	Mino-HA/CS material	1036:1054	Mino-HA/CS material	1036:1054	In vivo, Mino-HA/CS material showed better effect of promoting periodontal bone formation.					
35321974	3	27	theme	periodontal	654:664	arg1	defect					671:676	periodontal bone defect	654:676	periodontal bone defect	654:676	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	28	theme	defect	598:603	arg1	model					575:579	the rabbit model	564:579	the rabbit model of mandible bone defect	564:603	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	29	theme	materials	517:525	arg1	property					428:435	The physical and chemical property	402:435	The physical and chemical property	402:435	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	29	theme	materials	517:525	arg1	cytotoxicity					438:449	cytotoxicity	438:449	cytotoxicity	438:449	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	29	theme	materials	517:525	arg1	release					452:458	release	452:458	release of minocycline	452:473	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	29	theme	materials	517:525	arg1	examination					498:508	the bacteriostasis examination	479:508	the bacteriostasis examination of the materials	479:525	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	1	30	theme	bone	129:132	arg1	materials					141:149	bone repair materials	129:149	bone repair materials	129:149	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	1	31	theme	bone	228:231	arg1	repair					240:245	periodontal bone defect repair	216:245	periodontal bone defect repair	216:245	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	1	32	theme	repair	134:139	arg1	materials					141:149	bone repair materials	129:149	bone repair materials	129:149	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	1	33	theme	defect	233:238	arg1	repair					240:245	periodontal bone defect repair	216:245	periodontal bone defect repair	216:245	The aim was to obtain bone repair materials with sustained release of minocycline and evaluate the effect in periodontal bone defect repair.					
35321974	0	34	theme	bone	87:90	arg1	repair					99:104	periodontal bone defect repair	75:104	periodontal bone defect repair	75:104	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	3	35	theme	minocycline	463:473	arg1	property					428:435	The physical and chemical property	402:435	The physical and chemical property	402:435	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	35	theme	minocycline	463:473	arg1	cytotoxicity					438:449	cytotoxicity	438:449	cytotoxicity	438:449	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	35	theme	minocycline	463:473	arg1	release					452:458	release	452:458	release of minocycline	452:473	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	3	35	theme	minocycline	463:473	arg1	examination					498:508	the bacteriostasis examination	479:508	the bacteriostasis examination of the materials	479:525	The physical and chemical property, cytotoxicity, release of minocycline and the bacteriostasis examination of the materials were evaluated, they were applied to the rabbit model of mandible bone defect to evaluate their effects on the regeneration of periodontal bone defect.					
35321974	0	36	theme	periodontal	75:85	arg1	repair					99:104	periodontal bone defect repair	75:104	periodontal bone defect repair	75:104	Controlled release of minocycline in hydroxyapatite/chitosan composite for periodontal bone defect repair.					
35321974	2	37	theme	co-precipitation	377:392	arg1	method					394:399	the co-precipitation method	373:399	the co-precipitation method	373:399	Two complex material, hydroxyapatite/chitosan (HA/CS) and minocycline-hydroxyapatite/chitosan (Mino-HA/CS), were prepared by the co-precipitation method.					
35321974	6	38	theme	control	1011:1017	arg1	medium					1019:1024	control medium	1011:1024	control medium	1011:1024	Mino-HA/CS could promote the growth of osteoblasts effectively compared with control medium.					
35993391	5	0	theme	microfiber	581:590	arg1	spacing					592:598	a microfiber spacing	579:598	a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	579:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	6	1	theme	neuronal	1025:1032	arg1	firing					1034:1039	neuronal firing	1025:1039	neuronal firing	1025:1039	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	6	2	theme	neuronal	954:961	arg1	survival					963:970	neuronal survival	954:970	neuronal survival	954:970	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	6	3	theme	HA-SH	840:844	arg1	matrix					846:851	pure HA-SH matrix	835:851	pure HA-SH matrix	835:851	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	5	4	theme	poly	635:638	arg1	9.7 ± 0.2 µm					675:686	9.7 ± 0.2 µm	675:686	9.7 ± 0.2 µm	675:686	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	4	theme	poly	635:638	arg1	microfibers					662:672	poly(ɛ-caprolactone) (PCL) microfibers	635:672	poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	635:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	1	5	theme	neurological/neurodegenerative	163:192	arg1	diseases					194:201	neurological/neurodegenerative diseases	163:201	neurological/neurodegenerative diseases	163:201	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	6	6	theme	neuronal	806:813	arg1	low					828:830	low	828:830	low	828:830	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	6	6	theme	neuronal	806:813	arg1	viability					815:823	The neuronal viability	802:823	The neuronal viability	802:823	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	3	7	theme	ultra-soft	345:354	arg1	matrix					356:361	an ultra-soft matrix	342:361	an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame	342:439	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	4	8	theme	essential	495:503	arg1	component					505:513	an essential component	492:513	an essential component of the brain extracellular matrix (ECM)	492:553	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	3	9	theme	hyaluronic	382:391	arg1	HA-SH					399:403	HA-SH	399:403	HA-SH	399:403	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	3	9	theme	hyaluronic	382:391	arg1	acid					393:396	thiolated hyaluronic acid	372:396	thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame	372:439	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	1	10	dep	in	134:135	arg1	vivo					137:140	vivo	137:140	vivo	137:140	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	7	11	theme	standard	1171:1178	arg1	matrix					1180:1185	a gold standard matrix	1164:1185	a gold standard matrix for neuronal culture for over two decades	1164:1227	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	7	11	theme	standard	1171:1178	arg1	Matrigel					1154:1161	Matrigel	1154:1161	Matrigel	1154:1161	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	7	12	theme	HA-SH	1085:1089	arg1	able					1101:1104	able	1101:1104	able	1101:1104	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	7	12	theme	HA-SH	1085:1089	arg1	matrix					1091:1096	The astrocyte-seeded HA-SH matrix	1064:1096	The astrocyte-seeded HA-SH matrix	1064:1096	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	8	13	theme	3D	1241:1242	arg1	frame					1248:1252	this 3D MEW frame	1236:1252	this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes	1236:1307	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	6	14	theme	reinforced	905:914	arg1	construct					916:924	this reinforced construct	900:924	this reinforced construct	900:924	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	5	15	theme	melt	698:701	arg1	MEW					719:721	MEW	719:721	MEW	719:721	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	15	theme	melt	698:701	arg1	electrowriting					703:716	melt electrowriting	698:716	melt electrowriting (MEW)	698:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	16	theme	200 µm	603:608	arg1	spacing					592:598	a microfiber spacing	579:598	a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	579:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	17	theme	HA-SH	750:754	arg1	matrix					756:761	the HA-SH matrix	746:761	the HA-SH matrix which has an elastic modulus of 95 Pa	746:799	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	1	18	theme	3D	81:82	arg1	cultures					93:100	3D neuronal cultures	81:100	3D neuronal cultures	81:100	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	5	19	theme	95 Pa	795:799	arg1	modulus					784:790	an elastic modulus	773:790	an elastic modulus of 95 Pa	773:799	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	7	20	theme	neuronal	1119:1126	arg1	viability					1128:1136	the neuronal viability	1115:1136	the neuronal viability	1115:1136	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	6	21	theme	Ca2+	1050:1053	arg1	imaging					1055:1061	Ca2+ imaging	1050:1061	Ca2+ imaging	1050:1061	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	1	22	theme	neuronal	84:91	arg1	cultures					93:100	3D neuronal cultures	81:100	3D neuronal cultures	81:100	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	3	23	theme	microfiber	424:433	arg1	frame					435:439	a microfiber frame	422:439	a microfiber frame	422:439	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	0	24	theme	Hyaluronic	11:20	arg1	Matrices					33:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	4	25	theme	Hyaluronic	465:474	arg1	acid					476:479	Hyaluronic acid	465:479	Hyaluronic acid	465:479	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	5	26	theme	Box-shaped	556:565	arg1	frames					567:572	Box-shaped frames	556:572	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	556:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	6	27	theme	neurite	1005:1011	arg1	length					1013:1018	neurite length	1005:1018	neurite length	1005:1018	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	0	28	theme	Reinforced	0:9	arg1	Matrices					33:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	5	29	with	frames	567:572	arg1	spacing					592:598	a microfiber spacing	579:598	a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	579:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	8	30	theme	HA-SH	1265:1269	arg1	composite					1271:1279	HA-SH composite	1265:1279	HA-SH composite	1265:1279	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	1	31	theme	2D	215:216	arg1	models					218:223	2D models	215:223	2D models	215:223	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	4	32	theme	matrix	542:547	arg1	component					505:513	an essential component	492:513	an essential component of the brain extracellular matrix (ECM)	492:553	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	5	33	theme	microfibers	662:672	arg1	10-layers					622:630	10-layers	622:630	10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	622:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	0	34	theme	Acid-Based	22:31	arg1	Matrices					33:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices	0:40	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	2	35	theme	elastic	287:293	arg1	modulus					295:301	the low elastic modulus	279:301	the low elastic modulus (30-500 Pa) of the native brain	279:333	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	35	theme	elastic	287:293	arg1	30-500 Pa					304:312	30-500 Pa	304:312	30-500 Pa	304:312	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	35	theme	elastic	287:293	arg1	challenge					228:236	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	5	36	contain	has	769:771	arg1	matrix					756:761	the HA-SH matrix	746:761	the HA-SH matrix which has an elastic modulus of 95 Pa	746:799	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	36	contain	has	769:771	arg2	modulus					784:790	an elastic modulus	773:790	an elastic modulus of 95 Pa	773:799	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	5	37	theme	elastic	776:782	arg1	modulus					784:790	an elastic modulus	773:790	an elastic modulus of 95 Pa	773:799	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	0	38	theme	3D	50:51	arg1	Formation					70:78	3D Neuronal Network Formation	50:78	3D Neuronal Network Formation	50:78	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	2	39	theme	neuron	254:259	arg1	models					269:274	3D neuron culture models	251:274	3D neuron culture models	251:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	6	40	theme	network	973:979	arg1	formation					981:989	network formation	973:989	network formation	973:989	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	5	41	used	used	728:731	arg2	frames					567:572	Box-shaped frames	556:572	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW)	556:722	Box-shaped frames with a microfiber spacing of 200 µm composed of 10-layers of poly(ɛ-caprolactone) (PCL) microfibers (9.7 ± 0.2 µm) made via melt electrowriting (MEW) are used to reinforce the HA-SH matrix which has an elastic modulus of 95 Pa.					
35993391	8	42	theme	brain	1373:1377	arg1	diseases					1379:1386	brain diseases	1373:1386	brain diseases	1373:1386	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	3	43	used	used	459:462	arg2	matrix					356:361	an ultra-soft matrix	342:361	an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame	342:439	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	0	44	theme	Network	62:68	arg1	Formation					70:78	3D Neuronal Network Formation	50:78	3D Neuronal Network Formation	50:78	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	7	45	theme	neuronal	1191:1198	arg1	culture					1200:1206	neuronal culture	1191:1206	neuronal culture	1191:1206	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	0	46	theme	Neuronal	53:60	arg1	Formation					70:78	3D Neuronal Network Formation	50:78	3D Neuronal Network Formation	50:78	Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation.					
35993391	4	47	theme	extracellular	528:540	arg1	ECM					550:552	ECM	550:552	ECM	550:552	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	4	47	theme	extracellular	528:540	arg1	matrix					542:547	the brain extracellular matrix	518:547	the brain extracellular matrix (ECM)	518:553	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	8	48	theme	reproducible	1336:1347	arg1	system					1349:1354	a reliable and reproducible system	1321:1354	a reliable and reproducible system to further study brain diseases	1321:1386	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	4	49	theme	brain	522:526	arg1	ECM					550:552	ECM	550:552	ECM	550:552	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	4	49	theme	brain	522:526	arg1	matrix					542:547	the brain extracellular matrix	518:547	the brain extracellular matrix (ECM)	518:553	Hyaluronic acid represents an essential component of the brain extracellular matrix (ECM).					
35993391	7	50	theme	astrocyte-seeded	1068:1083	arg1	able					1101:1104	able	1101:1104	able	1101:1104	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	7	50	theme	astrocyte-seeded	1068:1083	arg1	matrix					1091:1096	The astrocyte-seeded HA-SH matrix	1064:1096	The astrocyte-seeded HA-SH matrix	1064:1096	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	2	51	theme	3D	251:252	arg1	models					269:274	3D neuron culture models	251:274	3D neuron culture models	251:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	1	52	theme	in	134:135	arg1	environment					142:152	the in vivo environment	130:152	the in vivo environment to study neurological/neurodegenerative diseases	130:201	3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models.					
35993391	2	53	theme	low	283:285	arg1	modulus					295:301	the low elastic modulus	279:301	the low elastic modulus (30-500 Pa) of the native brain	279:333	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	53	theme	low	283:285	arg1	30-500 Pa					304:312	30-500 Pa	304:312	30-500 Pa	304:312	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	53	theme	low	283:285	arg1	challenge					228:236	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	8	54	theme	MEW	1244:1246	arg1	frame					1248:1252	this 3D MEW frame	1236:1252	this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes	1236:1307	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	2	55	theme	native	322:327	arg1	brain					329:333	the native brain	318:333	the native brain	318:333	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	56	theme	brain	329:333	arg1	modulus					295:301	the low elastic modulus	279:301	the low elastic modulus (30-500 Pa) of the native brain	279:333	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	56	theme	brain	329:333	arg1	30-500 Pa					304:312	30-500 Pa	304:312	30-500 Pa	304:312	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	2	56	theme	brain	329:333	arg1	challenge					228:236	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models	226:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	8	57	theme	reliable	1323:1330	arg1	system					1349:1354	a reliable and reproducible system	1321:1354	a reliable and reproducible system to further study brain diseases	1321:1386	Thus, this 3D MEW frame reinforced HA-SH composite with neurons and astrocytes constitutes a reliable and reproducible system to further study brain diseases.					
35993391	6	58	theme	pure	835:838	arg1	matrix					846:851	pure HA-SH matrix	835:851	pure HA-SH matrix	835:851	The neuronal viability is low in pure HA-SH matrix, however, when astrocytes are pre-seeded below this reinforced construct, they significantly support neuronal survival, network formation quantified by neurite length, and neuronal firing shown by Ca2+ imaging.					
35993391	7	59	theme	Matrigel	1154:1161	arg1	level					1145:1149	the level	1141:1149	the level of Matrigel, a gold standard matrix for neuronal culture for over two decades	1141:1227	The astrocyte-seeded HA-SH matrix is able to match the neuronal viability to the level of Matrigel, a gold standard matrix for neuronal culture for over two decades.					
35993391	2	60	theme	culture	261:267	arg1	models					269:274	3D neuron culture models	251:274	3D neuron culture models	251:274	A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native brain.					
35993391	3	61	theme	thiolated	372:380	arg1	HA-SH					399:403	HA-SH	399:403	HA-SH	399:403	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
35993391	3	61	theme	thiolated	372:380	arg1	acid					393:396	thiolated hyaluronic acid	372:396	thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame	372:439	Here, an ultra-soft matrix based on thiolated hyaluronic acid (HA-SH) reinforced with a microfiber frame is formulated and used.					
36634800	5	0	theme	GAG	850:852	arg1	degradation					854:864	GAG degradation	850:864	GAG degradation as well as synthesis of HA and decorin	850:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	4	1	theme	brain	696:700	arg1	cerebellum					663:672	The cerebellum	659:672	The cerebellum	659:672	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	1	theme	brain	696:700	arg1	region					702:707	the most affected brain region	678:707	the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	678:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	0	2	theme	hyaluronic	107:116	arg1	acid					118:121	hyaluronic acid	107:121	hyaluronic acid	107:121	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	4	3	theme	Dse	773:775	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	3	theme	Dse	773:775	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	3	4	theme	gene	546:549	arg1	analysis					562:569	gene expression analysis	546:569	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	5	5	theme	decorin	897:903	arg1	degradation					854:864	GAG degradation	850:864	GAG degradation as well as synthesis of HA and decorin	850:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	5	5	theme	decorin	897:903	arg1	synthesis					877:885	synthesis	877:885	GAG degradation as well as synthesis of HA and decorin	850:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	7	6	theme	reversible	1325:1334	arg1	changes					1336:1342	subsequent partially reversible changes	1304:1342	subsequent partially reversible changes in CS-4S and in HA	1304:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	4	7	from	EAE	811:813	arg1	Gusb					778:781	Gusb	778:781	Gusb	778:781	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	7	from	EAE	811:813	arg1	Has2					798:801	Has2	798:801	Has2	798:801	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	7	from	EAE	811:813	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	7	from	EAE	811:813	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	7	from	EAE	811:813	arg1	Hexb					784:787	Hexb	784:787	Hexb	784:787	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	7	from	EAE	811:813	arg1	Dse					773:775	Dse	773:775	Dse	773:775	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	2	8	theme	neuroinflammation-mediated	288:313	arg1	changes					315:321	neuroinflammation-mediated changes	288:321	neuroinflammation-mediated changes in GAG composition and metabolism	288:355	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	6	9	from	peak	1108:1111	arg1	normalization					1119:1131	a normalization	1117:1131	a normalization	1117:1131	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	6	9	from	peak	1108:1111	arg1	reduction					1086:1094	a 3.6 % reduction	1078:1094	a 3.6 % reduction of CS-4S at peak	1078:1111	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	3	10	theme	EAE	511:513	arg1	phases					515:520	different EAE phases	501:520	different EAE phases	501:520	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	11	dep	analysis	562:569	arg1	microarray					572:581	microarray	572:581	microarray	572:581	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	11	dep	analysis	562:569	arg1	RT-qPCR					587:593	RT-qPCR	587:593	RT-qPCR	587:593	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	7	12	theme	Early	1221:1225	arg1	processes					1240:1248	Early inflammatory processes	1221:1248	Early inflammatory processes	1221:1248	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	8	13	from	modifications	1380:1392	arg1	CS					1397:1398	CS	1397:1398	CS	1397:1398	Targeting early modifications in CS could potentially mitigate progression of EAE/MS.					
36634800	4	14	theme	Has2	798:801	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	14	theme	Has2	798:801	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	7	15	from	metabolism	1269:1278	arg1	changes					1336:1342	subsequent partially reversible changes	1304:1342	subsequent partially reversible changes in CS-4S and in HA	1304:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	7	15	from	metabolism	1269:1278	arg1	stages					1293:1298	early EAE stages	1283:1298	early EAE stages	1283:1298	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	6	16	theme	CS-4S	1099:1103	arg1	normalization					1119:1131	a normalization	1117:1131	a normalization	1117:1131	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	6	16	theme	CS-4S	1099:1103	arg1	reduction					1086:1094	a 3.6 % reduction	1078:1094	a 3.6 % reduction of CS-4S at peak	1078:1111	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	8	17	theme	EAE/MS	1442:1447	arg1	progression					1427:1437	progression	1427:1437	progression of EAE/MS	1427:1447	Targeting early modifications in CS could potentially mitigate progression of EAE/MS.					
36634800	7	18	theme	inflammatory	1227:1238	arg1	processes					1240:1248	Early inflammatory processes	1221:1248	Early inflammatory processes	1221:1248	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	0	19	theme	Brain	0:4	arg1	inflammation					6:17	Brain inflammation	0:17	Brain inflammation	0:17	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	4	20	theme	peak	806:809	arg1	EAE					811:813	peak EAE	806:813	peak EAE	806:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	3	21	from	phases	515:520	arg1	Cerebellum					467:476	Cerebellum	467:476	Cerebellum	467:476	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	21	from	phases	515:520	arg1	forebrain					488:496	forebrain	488:496	forebrain	488:496	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	21	from	phases	515:520	arg1	mid-					479:482	mid-	479:482	mid-	479:482	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	5	22	theme	HA	890:891	arg1	degradation					854:864	GAG degradation	850:864	GAG degradation as well as synthesis of HA and decorin	850:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	5	22	theme	HA	890:891	arg1	synthesis					877:885	synthesis	877:885	GAG degradation as well as synthesis of HA and decorin	850:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	2	23	theme	encephalomyelitis	406:422	arg1	controls					457:464	controls	457:464	controls	457:464	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	23	theme	encephalomyelitis	406:422	arg1	model					373:377	the mouse model	363:377	the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice	363:452	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	7	24	theme	altered	1257:1263	arg1	metabolism					1269:1278	altered GAG metabolism	1257:1278	altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA	1257:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	8	25	theme	Targeting	1364:1372	arg1	modifications					1380:1392	Targeting early modifications	1364:1392	Targeting early modifications in CS	1364:1398	Targeting early modifications in CS could potentially mitigate progression of EAE/MS.					
36634800	4	26	theme	Dcn	790:792	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	26	theme	Dcn	790:792	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	2	27	theme	GAG	326:328	arg1	composition					330:340	GAG composition	326:340	GAG composition	326:340	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	4	28	theme	Cspg5	743:747	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	28	theme	Cspg5	743:747	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	7	29	from	stages	1293:1298	arg1	CS-4S					1347:1351	CS-4S	1347:1351	CS-4S	1347:1351	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	7	29	from	stages	1293:1298	arg1	HA					1360:1361	HA	1360:1361	HA	1360:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	2	30	theme	mice	449:452	arg1	controls					457:464	controls	457:464	controls	457:464	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	30	theme	mice	449:452	arg1	model					373:377	the mouse model	363:377	the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice	363:452	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	0	31	theme	glycosaminoglycan	42:58	arg1	metabolism					60:69	glycosaminoglycan metabolism	42:69	glycosaminoglycan metabolism	42:69	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	1	32	theme	inflammatory	214:225	arg1	disorders					227:235	inflammatory disorders	214:235	inflammatory disorders like multiple sclerosis (MS)	214:264	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	5	33	theme	genes	832:836	arg1	Upregulation					816:827	Upregulation	816:827	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin	816:903	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	2	34	theme	sham-immunized	434:447	arg1	mice					449:452	sham-immunized mice	434:452	sham-immunized mice	434:452	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	4	35	theme	affected	687:694	arg1	cerebellum					663:672	The cerebellum	659:672	The cerebellum	659:672	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	35	theme	affected	687:694	arg1	region					702:707	the most affected brain region	678:707	the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	678:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	7	36	theme	subsequent	1304:1313	arg1	changes					1336:1342	subsequent partially reversible changes	1304:1342	subsequent partially reversible changes in CS-4S and in HA	1304:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	0	37	from	changes	86:92	arg1	acid					118:121	hyaluronic acid	107:121	hyaluronic acid	107:121	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	0	37	from	changes	86:92	arg1	CS-4S					97:101	CS-4S	97:101	CS-4S	97:101	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	0	37	from	changes	86:92	arg1	metabolism					60:69	glycosaminoglycan metabolism	42:69	glycosaminoglycan metabolism	42:69	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	4	38	theme	Hexb	784:787	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	38	theme	Hexb	784:787	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	7	39	theme	EAE	1289:1291	arg1	stages					1293:1298	early EAE stages	1283:1298	early EAE stages	1283:1298	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	1	40	theme	disorders	227:235	arg1	progression					199:209	the progression	195:209	the progression of inflammatory disorders like multiple sclerosis (MS)	195:264	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	5	41	from	increments	1013:1022	arg1	HA					1027:1028	HA	1027:1028	HA	1027:1028	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	5	41	from	increments	1013:1022	arg1	CS					1006:1007	CS	1006:1007	CS	1006:1007	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	5	42	theme	severity-related	977:992	arg1	decrease					994:1001	a severity-related decrease	975:1001	a severity-related decrease in CS	975:1007	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	7	43	theme	early	1283:1287	arg1	stages					1293:1298	early EAE stages	1283:1298	early EAE stages	1283:1298	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	6	44	theme	disaccharide	1040:1051	arg1	quantification					1053:1066	Relative disaccharide quantification	1031:1066	Relative disaccharide quantification	1031:1066	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	2	45	theme	mouse	367:371	arg1	controls					457:464	controls	457:464	controls	457:464	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	45	theme	mouse	367:371	arg1	model					373:377	the mouse model	363:377	the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice	363:452	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	3	46	theme	HPLC	607:610	arg1	quantification					612:625	HPLC quantification	607:625	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	8	47	theme	early	1374:1378	arg1	modifications					1380:1392	Targeting early modifications	1364:1392	Targeting early modifications in CS	1364:1398	Targeting early modifications in CS could potentially mitigate progression of EAE/MS.					
36634800	7	48	theme	GAG	1265:1267	arg1	metabolism					1269:1278	altered GAG metabolism	1257:1278	altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA	1257:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	1	49	theme	brain	149:153	arg1	glycosaminoglycans					155:172	brain glycosaminoglycans	149:172	brain glycosaminoglycans (GAGs)	149:179	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	1	49	theme	brain	149:153	arg1	GAGs					175:178	GAGs	175:178	GAGs	175:178	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	3	50	theme	hyaluronic	637:646	arg1	HA					654:655	HA	654:655	HA	654:655	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	50	theme	hyaluronic	637:646	arg1	acid					648:651	hyaluronic acid	637:651	hyaluronic acid (HA)	637:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	4	51	from	upregulation	757:768	arg1	EAE					811:813	peak EAE	806:813	peak EAE	806:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	3	52	theme	different	501:509	arg1	phases					515:520	different EAE phases	501:520	different EAE phases	501:520	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	4	53	from	downregulation	719:732	arg1	EAE					811:813	peak EAE	806:813	peak EAE	806:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	6	54	theme	%	1084:1084	arg1	reduction					1086:1094	a 3.6 % reduction	1078:1094	a 3.6 % reduction of CS-4S at peak	1078:1111	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	3	55	theme	acid	648:651	arg1	quantification					612:625	HPLC quantification	607:625	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	55	theme	acid	648:651	arg1	analysis					562:569	gene expression analysis	546:569	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	56	theme	expression	551:560	arg1	analysis					562:569	gene expression analysis	546:569	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	2	57	from	changes	315:321	arg1	metabolism					346:355	metabolism	346:355	metabolism	346:355	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	57	from	changes	315:321	arg1	composition					330:340	GAG composition	326:340	GAG composition	326:340	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	1	58	theme	multiple	242:249	arg1	sclerosis					251:259	multiple sclerosis	242:259	multiple sclerosis (MS)	242:264	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	1	58	theme	multiple	242:249	arg1	MS					262:263	MS	262:263	MS	262:263	It remains uncertain how brain glycosaminoglycans (GAGs) contribute to the progression of inflammatory disorders like multiple sclerosis (MS).					
36634800	5	59	from	decrease	994:1001	arg1	HA					1027:1028	HA	1027:1028	HA	1027:1028	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	5	59	from	decrease	994:1001	arg1	CS					1006:1007	CS	1006:1007	CS	1006:1007	Upregulation of genes involved in GAG degradation as well as synthesis of HA and decorin persisted from onset to peak, and diminished at remission, suggesting a severity-related decrease in CS and increments in HA.					
36634800	6	60	theme	Relative	1031:1038	arg1	quantification					1053:1066	Relative disaccharide quantification	1031:1066	Relative disaccharide quantification	1031:1066	Relative disaccharide quantification confirmed a 3.6 % reduction of CS-4S at peak and a normalization during remission, while HA increased in both phases by 26.1 % and 17.6 %, respectively.					
36634800	3	61	theme	CS	630:631	arg1	quantification					612:625	HPLC quantification	607:625	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	3	61	theme	CS	630:631	arg1	analysis					562:569	gene expression analysis	546:569	gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA)	546:656	Cerebellum, mid- and forebrain at different EAE phases were investigated using gene expression analysis (microarray and RT-qPCR) as well as HPLC quantification of CS and hyaluronic acid (HA).					
36634800	2	62	theme	autoimmune	395:404	arg1	EAE					425:427	EAE	425:427	EAE	425:427	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	62	theme	autoimmune	395:404	arg1	encephalomyelitis					406:422	experimental autoimmune encephalomyelitis	382:422	experimental autoimmune encephalomyelitis (EAE)	382:428	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	7	63	from	changes	1336:1342	arg1	CS-4S					1347:1351	CS-4S	1347:1351	CS-4S	1347:1351	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	7	63	from	changes	1336:1342	arg1	HA					1360:1361	HA	1360:1361	HA	1360:1361	Early inflammatory processes led to altered GAG metabolism in early EAE stages and subsequent partially reversible changes in CS-4S and in HA.					
36634800	0	64	theme	subsequent	75:84	arg1	changes					86:92	subsequent changes	75:92	subsequent changes in CS-4S and hyaluronic acid	75:121	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	0	65	from	alterations	27:37	arg1	acid					118:121	hyaluronic acid	107:121	hyaluronic acid	107:121	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	0	65	from	alterations	27:37	arg1	CS-4S					97:101	CS-4S	97:101	CS-4S	97:101	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	0	65	from	alterations	27:37	arg1	metabolism					60:69	glycosaminoglycan metabolism	42:69	glycosaminoglycan metabolism	42:69	Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.					
36634800	4	66	theme	Gusb	778:781	arg1	upregulation					757:768	an upregulation	754:768	an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE	754:813	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	4	66	theme	Gusb	778:781	arg1	downregulation					719:732	a downregulation	717:732	a downregulation of Bcan, Cspg5	717:747	The cerebellum was the most affected brain region showing a downregulation of Bcan, Cspg5, and an upregulation of Dse, Gusb, Hexb, Dcn and Has2 at peak EAE.					
36634800	2	67	theme	experimental	382:393	arg1	EAE					425:427	EAE	425:427	EAE	425:427	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36634800	2	67	theme	experimental	382:393	arg1	encephalomyelitis					406:422	experimental autoimmune encephalomyelitis	382:422	experimental autoimmune encephalomyelitis (EAE)	382:428	We investigated here neuroinflammation-mediated changes in GAG composition and metabolism using the mouse model of experimental autoimmune encephalomyelitis (EAE) and sham-immunized mice as controls.					
36770616	4	0	theme	enzyme	475:480	arg1	loading					482:488	an enzyme loading	472:488	an enzyme loading of 0.974	472:497	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	5	1	theme	Segal	510:514	arg1	formula					516:522	the Segal formula	506:522	the Segal formula	506:522	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	4	2	theme	0.974	493:497	arg1	loading					482:488	an enzyme loading	472:488	an enzyme loading of 0.974	472:497	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	4	2	theme	0.974	493:497	arg1	loading					450:456	a solid loading	442:456	a solid loading of 15 g/L	442:466	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	1	3	from	pulp	165:168	arg1	CNF					139:141	CNF	139:141	CNF	139:141	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	1	3	from	pulp	165:168	arg1	nanofibrils					126:136	cellulose nanofibrils	116:136	cellulose nanofibrils (CNF) from kraft cellulose pulp	116:168	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	7	4	theme	synergistic	800:810	arg1	interactions					812:823	synergistic interactions	800:823	synergistic interactions between the enzymes involved in nanocellulose production	800:880	Finally, synergistic interactions between the enzymes involved in nanocellulose production were demonstrated, with Colby factor values greater than one.					
36770616	3	5	theme	CNF	352:354	arg1	process					367:373	the CNF production process	348:373	the CNF production process	348:373	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	6	theme	production	356:365	arg1	process					367:373	the CNF production process	348:373	the CNF production process	348:373	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	4	7	theme	g/L	464:466	arg1	loading					482:488	an enzyme loading	472:488	an enzyme loading of 0.974	472:497	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	4	7	theme	g/L	464:466	arg1	loading					450:456	a solid loading	442:456	a solid loading of 15 g/L	442:466	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	5	8	theme	CNF	562:564	arg1	CrI					550:552	CrI	550:552	CrI	550:552	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	5	8	theme	CNF	562:564	arg1	index					543:547	the crystallinity index	525:547	the crystallinity index (CrI) of the CNF	525:564	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	5	8	theme	CNF	562:564	arg1	%					613:613	80.87%	608:613	80.87%	608:613	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	7	9	theme	factor	912:917	arg1	values					919:924	Colby factor values	906:924	Colby factor values greater than one	906:941	Finally, synergistic interactions between the enzymes involved in nanocellulose production were demonstrated, with Colby factor values greater than one.					
36770616	6	10	theme	enzymatic	723:731	arg1	hydrolysis					733:742	enzymatic hydrolysis	723:742	enzymatic hydrolysis	723:742	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	6	11	theme	CNF	644:646	arg1	nm					693:694	550-600 nm	685:694	550-600 nm	685:694	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	6	11	theme	CNF	644:646	arg1	diameter					628:635	The average diameter	616:635	The average diameter of the CNF prepared by enzymatic hydrolysis	616:679	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	2	12	dep	%	253:253	arg1	endoglucanase					255:267	endoglucanase	255:267	69% endoglucanase	251:267	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
36770616	5	13	theme	X-ray	584:588	arg1	diffraction					590:600	X-ray diffraction	584:600	X-ray diffraction	584:600	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	1	14	theme	centroid	192:199	arg1	design					217:222	a centroid simplex mixture design	190:222	a centroid simplex mixture design	190:222	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	0	15	theme	Cellulose	32:40	arg1	Assessment					64:73	Cellulose Nanofibril Production Assessment	32:73	Cellulose Nanofibril Production Assessment	32:73	Endo-Exoglucanase Synergism for Cellulose Nanofibril Production Assessment and Characterization.					
36770616	7	16	theme	Colby	906:910	arg1	values					919:924	Colby factor values	906:924	Colby factor values greater than one	906:941	Finally, synergistic interactions between the enzymes involved in nanocellulose production were demonstrated, with Colby factor values greater than one.					
36770616	1	17	theme	cellulose	116:124	arg1	CNF					139:141	CNF	139:141	CNF	139:141	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	1	17	theme	cellulose	116:124	arg1	nanofibrils					126:136	cellulose nanofibrils	116:136	cellulose nanofibrils (CNF) from kraft cellulose pulp	116:168	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	6	18	theme	average	620:626	arg1	nm					693:694	550-600 nm	685:694	550-600 nm	685:694	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	6	18	theme	average	620:626	arg1	diameter					628:635	The average diameter	616:635	The average diameter of the CNF prepared by enzymatic hydrolysis	616:679	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	1	19	theme	simplex	201:207	arg1	design					217:222	a centroid simplex mixture design	190:222	a centroid simplex mixture design	190:222	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	7	20	theme	greater	926:932	arg1	values					919:924	Colby factor values	906:924	Colby factor values greater than one	906:941	Finally, synergistic interactions between the enzymes involved in nanocellulose production were demonstrated, with Colby factor values greater than one.					
36770616	4	21	theme	solid	444:448	arg1	loading					450:456	a solid loading	442:456	a solid loading of 15 g/L	442:466	It thus corresponded to a solid loading of 15 g/L and an enzyme loading of 0.974.					
36770616	1	22	theme	mixture	209:215	arg1	design					217:222	a centroid simplex mixture design	190:222	a centroid simplex mixture design	190:222	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	0	23	theme	Production	53:62	arg1	Assessment					64:73	Cellulose Nanofibril Production Assessment	32:73	Cellulose Nanofibril Production Assessment	32:73	Endo-Exoglucanase Synergism for Cellulose Nanofibril Production Assessment and Characterization.					
36770616	0	24	theme	Nanofibril	42:51	arg1	Assessment					64:73	Cellulose Nanofibril Production Assessment	32:73	Cellulose Nanofibril Production Assessment	32:73	Endo-Exoglucanase Synergism for Cellulose Nanofibril Production Assessment and Characterization.					
36770616	3	25	theme	higher	390:395	arg1	index					411:415	a higher crystallinity index	388:415	a higher crystallinity index	388:415	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	26	theme	composite	303:311	arg1	CCRD					332:335	CCRD	332:335	CCRD	332:335	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	26	theme	composite	303:311	arg1	design					324:329	The central composite rotational design	291:329	The central composite rotational design (CCRD)	291:336	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	2	27	theme	enzyme	229:234	arg1	blend					236:240	The enzyme blend	225:240	The enzyme blend	225:240	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
36770616	3	28	theme	crystallinity	397:409	arg1	index					411:415	a higher crystallinity index	388:415	a higher crystallinity index	388:415	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	29	theme	rotational	313:322	arg1	CCRD					332:335	CCRD	332:335	CCRD	332:335	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	29	theme	rotational	313:322	arg1	design					324:329	The central composite rotational design	291:329	The central composite rotational design (CCRD)	291:336	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	6	30	theme	250-300	779:785	arg1	one					707:709	the one	703:709	the one produced by enzymatic hydrolysis and with ultrasonic dispersion	703:773	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	6	30	theme	250-300	779:785	arg1	nm					787:788	250-300 nm	779:788	250-300 nm	779:788	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	1	31	dep	study	99:103	arg1	produce					108:114	produce	108:114	to produce cellulose nanofibrils (CNF) from kraft cellulose pulp	105:168	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	1	32	theme	kraft	149:153	arg1	pulp					165:168	kraft cellulose pulp	149:168	kraft cellulose pulp	149:168	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	5	33	theme	crystallinity	529:541	arg1	CrI					550:552	CrI	550:552	CrI	550:552	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	5	33	theme	crystallinity	529:541	arg1	index					543:547	the crystallinity index	525:547	the crystallinity index (CrI) of the CNF	525:564	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	5	33	theme	crystallinity	529:541	arg1	%					613:613	80.87%	608:613	80.87%	608:613	Using the Segal formula, the crystallinity index (CrI) of the CNF was determined by X-ray diffraction to be 80.87%.					
36770616	7	34	theme	nanocellulose	857:869	arg1	production					871:880	nanocellulose production	857:880	nanocellulose production	857:880	Finally, synergistic interactions between the enzymes involved in nanocellulose production were demonstrated, with Colby factor values greater than one.					
36770616	3	35	theme	central	295:301	arg1	CCRD					332:335	CCRD	332:335	CCRD	332:335	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	3	35	theme	central	295:301	arg1	design					324:329	The central composite rotational design	291:329	The central composite rotational design (CCRD)	291:336	The central composite rotational design (CCRD) optimized the CNF production process by achieving a higher crystallinity index.					
36770616	6	36	theme	ultrasonic	753:762	arg1	dispersion					764:773	ultrasonic dispersion	753:773	ultrasonic dispersion	753:773	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	2	37	dep	%	275:275	arg1	exoglucanase					277:288	exoglucanase	277:288	31% exoglucanase	273:288	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
36770616	6	38	theme	enzymatic	660:668	arg1	hydrolysis					670:679	enzymatic hydrolysis	660:679	enzymatic hydrolysis	660:679	The average diameter of the CNF prepared by enzymatic hydrolysis was 550-600 nm, while the one produced by enzymatic hydrolysis and with ultrasonic dispersion was 250-300 nm.					
36770616	1	39	theme	cellulose	155:163	arg1	pulp					165:168	kraft cellulose pulp	149:168	kraft cellulose pulp	149:168	A study to produce cellulose nanofibrils (CNF) from kraft cellulose pulp was conducted using a centroid simplex mixture design.					
36770616	2	40	contain	contains	242:249	arg1	blend					236:240	The enzyme blend	225:240	The enzyme blend	225:240	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
36770616	2	40	contain	contains	242:249	arg2	%					253:253	69%	251:253	69% endoglucanase	251:267	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
36770616	2	40	contain	contains	242:249	arg2	%					275:275	31%	273:275	31% exoglucanase	273:288	The enzyme blend contains 69% endoglucanase and 31% exoglucanase.					
35926678	0	0	theme	deposition	75:84	arg1	printing					98:105	fused deposition modeling 3D printing	69:105	fused deposition modeling 3D printing	69:105	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	4	1	theme	chain	619:623	arg1	ADR4468					634:640	the chain extender ADR4468	615:640	the chain extender ADR4468 (CE)	615:645	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	4	1	theme	chain	619:623	arg1	CE					643:644	CE	643:644	CE	643:644	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	0	2	theme	fused	69:73	arg1	printing					98:105	fused deposition modeling 3D printing	69:105	fused deposition modeling 3D printing	69:105	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	3	3	dep	preparation	376:386	arg1	dedicated					503:511	dedicated	503:511	dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%	503:599	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	4	dep	technology	537:546	arg1	PBAT					570:573	PBAT	570:573	PBAT	570:573	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	4	dep	technology	537:546	arg1	PLA					566:568	PLA	566:568	PLA	566:568	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	5	5	from	break	846:850	arg1	elongation					832:841	elongation	832:841	elongation at break and the 190 % raise in impact strength	832:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	5	from	break	846:850	arg1	increase					820:827	113 % increase	814:827	113 % increase in elongation at break and the 190 % raise in impact strength	814:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	0	6	theme	3D	95:96	arg1	printing					98:105	fused deposition modeling 3D printing	69:105	fused deposition modeling 3D printing	69:105	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	3	7	theme	3D	525:526	arg1	ratio					553:557	the ratio	549:557	the ratio of TPS	549:564	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	7	theme	3D	525:526	arg1	fixed					579:583	fixed	579:583	fixed	579:583	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	7	theme	3D	525:526	arg1	technology					537:546	the FDM 3D printing technology	517:546	the FDM 3D printing technology	517:546	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	0	8	theme	modeling	86:93	arg1	printing					98:105	fused deposition modeling 3D printing	69:105	fused deposition modeling 3D printing	69:105	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	6	9	theme	melt	972:975	arg1	strength					977:984	melt strength	972:984	melt strength	972:984	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	5	10	theme	%	818:818	arg1	increase					820:827	113 % increase	814:827	113 % increase in elongation at break and the 190 % raise in impact strength	814:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	7	11	theme	TPS-based	1055:1063	arg1	filament					1065:1072	TPS-based filament	1055:1072	TPS-based filament	1055:1072	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	1	12	theme	3D	108:109	arg1	technology					120:129	3D printing technology	108:129	3D printing technology	108:129	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	1	12	theme	3D	108:109	arg1	method					166:171	a highly flexible method	148:171	a highly flexible method which can achieve a various customized end products	148:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	6	13	theme	viscosity	958:966	arg1	degree					940:945	the maximum degree	928:945	the maximum degree of complex viscosity and melt strength	928:984	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	6	14	theme	rheological	900:910	arg1	analysis					912:919	Dynamic rheological analysis	892:919	Dynamic rheological analysis	892:919	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	1	15	theme	flexible	157:164	arg1	technology					120:129	3D printing technology	108:129	3D printing technology	108:129	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	1	15	theme	flexible	157:164	arg1	method					166:171	a highly flexible method	148:171	a highly flexible method which can achieve a various customized end products	148:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	7	16	theme	filament	1065:1072	arg1	printability					1039:1050	The successful printability	1024:1050	The successful printability of TPS-based filament	1024:1072	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	3	17	theme	thermoplastic	391:403	arg1	PBAT					482:485	PBAT	482:485	PBAT	482:485	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	17	theme	thermoplastic	391:403	arg1	acid					430:433	lactic acid	423:433	lactic acid	423:433	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	17	theme	thermoplastic	391:403	arg1	starch					405:410	thermoplastic starch	391:410	thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite	391:496	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	17	theme	thermoplastic	391:403	arg1	butyleneadipate-co-terephthalate					447:478	butyleneadipate-co-terephthalate	447:478	butyleneadipate-co-terephthalate	447:478	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	17	theme	thermoplastic	391:403	arg1	TPS					413:415	TPS	413:415	TPS	413:415	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	17	theme	thermoplastic	391:403	arg1	PLA					437:439	PLA	437:439	PLA	437:439	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	5	18	from	%	864:864	arg1	elongation					832:841	elongation	832:841	elongation at break and the 190 % raise in impact strength	832:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	18	from	%	864:864	arg1	increase					820:827	113 % increase	814:827	113 % increase in elongation at break and the 190 % raise in impact strength	814:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	19	theme	blends	766:771	arg1	properties					752:761	The mechanical properties	737:761	The mechanical properties of blends	737:771	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	0	20	theme	starch	14:19	arg1	based					21:25	Thermoplastic starch based	0:25	Thermoplastic starch based	0:25	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	7	21	theme	accurate	1094:1101	arg1	samples					1124:1130	accurate and complex printing samples	1094:1130	accurate and complex printing samples	1094:1130	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	3	22	theme	printing	528:535	arg1	ratio					553:557	the ratio	549:557	the ratio of TPS	549:564	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	22	theme	printing	528:535	arg1	fixed					579:583	fixed	579:583	fixed	579:583	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	22	theme	printing	528:535	arg1	technology					537:546	the FDM 3D printing technology	517:546	the FDM 3D printing technology	517:546	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	0	23	theme	Thermoplastic	0:12	arg1	based					21:25	Thermoplastic starch based	0:25	Thermoplastic starch based	0:25	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	6	24	theme	CE	1006:1007	arg1	content					995:1001	the content	991:1001	the content of CE	991:1007	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	5	25	dep	break	846:850	arg1	raise					866:870	raise	866:870	raise in impact strength	866:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	26	theme	CE	806:807	arg1	addition					794:801	the addition	790:801	the addition of CE	790:807	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	3	27	theme	FDM	521:523	arg1	ratio					553:557	the ratio	549:557	the ratio of TPS	549:564	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	27	theme	FDM	521:523	arg1	fixed					579:583	fixed	579:583	fixed	579:583	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	27	theme	FDM	521:523	arg1	technology					537:546	the FDM 3D printing technology	517:546	the FDM 3D printing technology	517:546	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	6	28	theme	maximum	932:938	arg1	degree					940:945	the maximum degree	928:945	the maximum degree of complex viscosity and melt strength	928:984	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	7	29	theme	successful	1028:1037	arg1	printability					1039:1050	The successful printability	1024:1050	The successful printability of TPS-based filament	1024:1072	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	2	30	theme	environmental	295:307	arg1	footprint					309:317	the environmental footprint	291:317	the environmental footprint of the end 3D printing products	291:349	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	2	31	theme	printing	333:340	arg1	products					342:349	the end 3D printing products	322:349	the end 3D printing products	322:349	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	5	32	theme	mechanical	741:750	arg1	properties					752:761	The mechanical properties	737:761	The mechanical properties of blends	737:771	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	4	33	theme	3D	715:716	arg1	filament					727:734	3D printing filament	715:734	3D printing filament	715:734	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	8	34	theme	renewable	1180:1188	arg1	filaments					1190:1198	highly renewable filaments	1173:1198	highly renewable filaments	1173:1198	This paper provided a method to prepare highly renewable filaments for 3D printing.					
35926678	1	35	theme	various	193:199	arg1	products					216:223	a various customized end products	191:223	a various customized end products	191:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	3	36	theme	lactic	423:428	arg1	acid					430:433	lactic acid	423:433	lactic acid	423:433	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	36	theme	lactic	423:428	arg1	starch					405:410	thermoplastic starch	391:410	thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite	391:496	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	1	37	theme	customized	201:210	arg1	products					216:223	a various customized end products	191:223	a various customized end products	191:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	0	38	theme	renewable	46:54	arg1	filament					56:63	a highly renewable filament	37:63	a highly renewable filament for fused deposition modeling 3D printing	37:105	Thermoplastic starch based blends as a highly renewable filament for fused deposition modeling 3D printing.					
35926678	3	39	from	%	599:599	arg1	fixed					579:583	fixed	579:583	fixed	579:583	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	39	from	%	599:599	arg1	technology					537:546	the FDM 3D printing technology	517:546	the FDM 3D printing technology	517:546	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	2	40	theme	products	342:349	arg1	footprint					309:317	the environmental footprint	291:317	the environmental footprint of the end 3D printing products	291:349	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	8	41	theme	3D	1204:1205	arg1	printing					1207:1214	3D printing	1204:1214	3D printing	1204:1214	This paper provided a method to prepare highly renewable filaments for 3D printing.					
35926678	4	42	theme	printing	718:725	arg1	filament					727:734	3D printing filament	715:734	3D printing filament	715:734	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	1	43	theme	printing	111:118	arg1	technology					120:129	3D printing technology	108:129	3D printing technology	108:129	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	1	43	theme	printing	111:118	arg1	method					166:171	a highly flexible method	148:171	a highly flexible method which can achieve a various customized end products	148:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	4	44	theme	blends	691:696	arg1	brittleness					672:682	the brittleness	668:682	the brittleness of the blends to obtain better 3D printing filament	668:734	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	2	45	theme	materials	254:262	arg1	employment					230:239	The employment	226:239	The employment of bio-based materials	226:262	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	6	46	theme	Dynamic	892:898	arg1	analysis					912:919	Dynamic rheological analysis	892:919	Dynamic rheological analysis	892:919	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	2	47	theme	3D	330:331	arg1	products					342:349	the end 3D printing products	322:349	the end 3D printing products	322:349	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	1	48	theme	end	212:214	arg1	products					216:223	a various customized end products	191:223	a various customized end products	191:223	3D printing technology is considered as a highly flexible method which can achieve a various customized end products.					
35926678	3	49	theme	50:40:10 wt	588:598	arg1	%					599:599	50:40:10 wt%	588:599	50:40:10 wt%	588:599	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	2	50	theme	bio-based	244:252	arg1	materials					254:262	bio-based materials	244:262	bio-based materials	244:262	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	2	51	theme	end	326:328	arg1	products					342:349	the end 3D printing products	322:349	the end 3D printing products	322:349	The employment of bio-based materials can significantly decrease the environmental footprint of the end 3D printing products.					
35926678	5	52	from	increase	820:827	arg1	elongation					832:841	elongation	832:841	elongation at break and the 190 % raise in impact strength	832:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	52	from	increase	820:827	arg1	%					864:864	the 190 %	856:864	the 190 %	856:864	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	52	from	increase	820:827	arg1	break					846:850	break	846:850	break	846:850	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	5	53	theme	113 	814:817	arg1	%					818:818	%	818:818	%	818:818	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	7	54	theme	complex	1107:1113	arg1	samples					1124:1130	accurate and complex printing samples	1094:1130	accurate and complex printing samples	1094:1130	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	6	55	theme	strength	977:984	arg1	degree					940:945	the maximum degree	928:945	the maximum degree of complex viscosity and melt strength	928:984	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	3	56	theme	TPS	562:564	arg1	ratio					553:557	the ratio	549:557	the ratio of TPS	549:564	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	3	56	theme	TPS	562:564	arg1	technology					537:546	the FDM 3D printing technology	517:546	the FDM 3D printing technology	517:546	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	6	57	theme	complex	950:956	arg1	viscosity					958:966	complex viscosity	950:966	complex viscosity	950:966	Dynamic rheological analysis showed the maximum degree of complex viscosity and melt strength when the content of CE reached 1 wt%.					
35926678	3	58	theme	starch	405:410	arg1	composite					488:496	thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite	391:496	thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite	391:496	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	5	59	theme	impact	875:880	arg1	strength					882:889	impact strength	875:889	impact strength	875:889	The mechanical properties of blends were improved by the addition of CE with 113 % increase in elongation at break and the 190 % raise in impact strength.					
35926678	3	60	theme	composite	488:496	arg1	preparation					376:386	the preparation	372:386	the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%	372:599	This study presents the preparation of thermoplastic starch (TPS)/poly(lactic acid) (PLA)/poly(butyleneadipate-co-terephthalate) (PBAT) composite that dedicated for the FDM 3D printing technology, the ratio of TPS:PLA:PBAT was fixed at 50:40:10 wt%.					
35926678	7	61	theme	printing	1115:1122	arg1	samples					1124:1130	accurate and complex printing samples	1094:1130	accurate and complex printing samples	1094:1130	The successful printability of TPS-based filament was demonstrated by accurate and complex printing samples.					
35926678	4	62	theme	extender	625:632	arg1	ADR4468					634:640	the chain extender ADR4468	615:640	the chain extender ADR4468 (CE)	615:645	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35926678	4	62	theme	extender	625:632	arg1	CE					643:644	CE	643:644	CE	643:644	In addition, the chain extender ADR4468 (CE) was added to improve the brittleness of the blends to obtain better 3D printing filament.					
35730493	7	0	theme	traditional	1222:1232	arg1	dressing					1240:1247	traditional wound dressing	1222:1247	traditional wound dressing	1222:1247	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	1	theme	liquid	1121:1126	arg1	absorption					1128:1137	liquid absorption	1121:1137	liquid absorption	1121:1137	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	2	theme	PCL	1027:1029	arg1	dressing					1050:1057	PCL membrane composite dressing	1027:1057	PCL membrane composite dressing	1027:1057	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	3	theme	membrane	1031:1038	arg1	dressing					1050:1057	PCL membrane composite dressing	1027:1057	PCL membrane composite dressing	1027:1057	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	4	4	theme	wound	550:554	arg1	healing					556:562	wound healing	550:562	wound healing materials	550:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	0	5	theme	wound	77:81	arg1	dressing					83:90	wound dressing	77:90	wound dressing	77:90	An asymmetric wettable PCL/chitosan composite scaffold loaded with IGF-2 for wound dressing.					
35730493	4	6	theme	PCL	466:468	arg1	dressing					501:508	PCL nanofibrous membrane composite dressing	466:508	PCL nanofibrous membrane composite dressing	466:508	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	5	7	theme	composite	635:643	arg1	dressing					645:652	the composite dressing	631:652	the composite dressing	631:652	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	2	8	from	one	187:189	arg1	fact					150:153	fact	150:153	fact	150:153	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	6	9	theme	CS	897:898	arg1	sponge					900:905	the CS sponge	893:905	the CS sponge	893:905	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	5	10	theme	dressing	645:652	arg1	surfaces					619:626	The hydrophobic surfaces	603:626	The hydrophobic surfaces of the composite dressing	603:652	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	4	11	theme	chitosan	441:448	arg1	CS					451:452	CS	451:452	CS	451:452	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	4	11	theme	chitosan	441:448	arg1	type					433:436	a type	431:436	a type of chitosan (CS) sponge	431:460	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	4	12	theme	healing	556:562	arg1	materials					564:572	wound healing materials	550:572	wound healing materials	550:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	3	13	theme	exudates	321:328	arg1	absorption					300:309	the absorption	296:309	the absorption of excess exudates and maintenance of optimal moisture at the wound	296:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	7	14	theme	transmission	1098:1109	arg1	rate					1111:1114	vapor transmission rate	1092:1114	vapor transmission rate	1092:1114	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	5	15	theme	CS	774:775	arg1	sponge					777:782	the CS sponge	770:782	the CS sponge	770:782	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	7	16	theme	promising	1197:1205	arg1	alternative					1207:1217	a promising alternative	1195:1217	a promising alternative to traditional wound dressing	1195:1247	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	16	theme	promising	1197:1205	arg1	potential					1182:1190	its potential	1178:1190	its potential	1178:1190	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	6	17	dep	fibroblasts	946:956	arg1	fibroblasts					946:956	fibroblasts migration and proliferation	946:984	fibroblasts migration and proliferation	946:984	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	17	dep	fibroblasts	946:956	arg1	proliferation					972:984	proliferation	972:984	proliferation	972:984	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	17	dep	fibroblasts	946:956	arg1	migration					958:966	migration	958:966	migration	958:966	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	5	18	theme	hydrophobic	607:617	arg1	surfaces					619:626	The hydrophobic surfaces	603:626	The hydrophobic surfaces of the composite dressing	603:652	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	0	19	theme	asymmetric	3:12	arg1	scaffold					46:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold loaded with IGF-2 for wound dressing.					
35730493	7	20	theme	wound	1234:1238	arg1	dressing					1240:1247	traditional wound dressing	1222:1247	traditional wound dressing	1222:1247	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	4	21	with	dressing	501:508	arg1	surfaces					538:545	asymmetric wettability surfaces	515:545	asymmetric wettability surfaces as wound healing materials	515:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	5	22	dep	were	654:657	arg1	whereas					735:741	whereas	735:741	whereas	735:741	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	4	23	theme	asymmetric	515:524	arg1	surfaces					538:545	asymmetric wettability surfaces	515:545	asymmetric wettability surfaces as wound healing materials	515:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	0	24	theme	PCL/chitosan	23:34	arg1	scaffold					46:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold loaded with IGF-2 for wound dressing.					
35730493	6	25	theme	growth	856:861	arg1	IGF-2					873:877	IGF-2	873:877	IGF-2	873:877	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	25	theme	growth	856:861	arg1	factor-2					863:870	Insulin-like growth factor-2	843:870	Insulin-like growth factor-2 (IGF-2)	843:878	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	5	26	theme	transmission	716:727	arg1	rate					729:732	the water vapor transmission rate	700:732	the water vapor transmission rate	700:732	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	3	27	theme	optimal	349:355	arg1	moisture					357:364	optimal moisture	349:364	optimal moisture	349:364	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	7	28	theme	excellent	1063:1071	arg1	cytocompatibility					1073:1089	excellent cytocompatibility	1063:1089	excellent cytocompatibility	1063:1089	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	1	29	theme	effective	96:104	arg1	essential					118:126	essential	118:126	essential	118:126	An effective dressing is essential for wound healing.					
35730493	1	29	theme	effective	96:104	arg1	dressing					106:113	An effective dressing	93:113	An effective dressing	93:113	An effective dressing is essential for wound healing.					
35730493	3	30	theme	moisture	357:364	arg1	maintenance					334:344	maintenance	334:344	maintenance of optimal moisture at the wound	334:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	3	30	theme	moisture	357:364	arg1	exudates					321:328	excess exudates	314:328	excess exudates	314:328	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	7	31	contain	had	1059:1061	arg2	absorption					1128:1137	liquid absorption	1121:1137	liquid absorption	1121:1137	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	31	contain	had	1059:1061	arg2	cytocompatibility					1073:1089	excellent cytocompatibility	1063:1089	excellent cytocompatibility	1063:1089	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	31	contain	had	1059:1061	arg2	rate					1111:1114	vapor transmission rate	1092:1114	vapor transmission rate	1092:1114	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	31	contain	had	1059:1061	arg1	dressing					1050:1057	PCL membrane composite dressing	1027:1057	PCL membrane composite dressing	1027:1057	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	31	contain	had	1059:1061	arg1	sponge					1016:1021	the fabricated CS sponge	998:1021	the fabricated CS sponge	998:1021	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	4	32	theme	wettability	526:536	arg1	surfaces					538:545	asymmetric wettability surfaces	515:545	asymmetric wettability surfaces as wound healing materials	515:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	5	33	theme	water	704:708	arg1	rate					729:732	the water vapor transmission rate	700:732	the water vapor transmission rate	700:732	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	2	34	theme	wettability	160:170	arg1	factors					213:219	the most important factors	194:219	the most important factors of a wound dressing	194:239	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	2	34	theme	wettability	160:170	arg1	one					187:189	one	187:189	one	187:189	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	2	34	theme	wettability	160:170	arg1	performance					172:182	the wettability performance	156:182	the wettability performance	156:182	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	5	35	theme	vapor	710:714	arg1	rate					729:732	the water vapor transmission rate	700:732	the water vapor transmission rate	700:732	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	0	36	theme	composite	36:44	arg1	scaffold					46:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold loaded with IGF-2 for wound dressing.					
35730493	4	37	theme	membrane	482:489	arg1	dressing					501:508	PCL nanofibrous membrane composite dressing	466:508	PCL nanofibrous membrane composite dressing	466:508	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	3	38	theme	water	394:398	arg1	evaporation					400:410	water evaporation	394:410	water evaporation	394:410	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	4	39	theme	type	433:436	arg1	sponge					455:460	a type of chitosan (CS) sponge	431:460	a type of chitosan (CS) sponge	431:460	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	2	40	theme	factors	213:219	arg1	factors					213:219	the most important factors	194:219	the most important factors of a wound dressing	194:239	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	2	40	theme	factors	213:219	arg1	one					187:189	one	187:189	one	187:189	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	2	40	theme	factors	213:219	arg1	performance					172:182	the wettability performance	156:182	the wettability performance	156:182	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	7	41	theme	CS	1013:1014	arg1	sponge					1016:1021	the fabricated CS sponge	998:1021	the fabricated CS sponge	998:1021	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	5	42	theme	water-absorbing	815:829	arg1	capability					831:840	water-absorbing capability	815:840	water-absorbing capability	815:840	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	5	43	theme	sponge	777:782	arg1	surface					759:765	the hydrophilic surface	743:765	the hydrophilic surface of the CS sponge	743:782	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	3	44	theme	maintenance	334:344	arg1	absorption					300:309	the absorption	296:309	the absorption of excess exudates and maintenance of optimal moisture at the wound	296:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	3	45	theme	dressing	279:286	arg1	functions					258:266	The fundamental functions	242:266	The fundamental functions of a wound dressing	242:286	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	5	46	theme	hydrophilic	747:757	arg1	surface					759:765	the hydrophilic surface	743:765	the hydrophilic surface of the CS sponge	743:782	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	2	47	theme	important	203:211	arg1	factors					213:219	the most important factors	194:219	the most important factors of a wound dressing	194:239	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	3	48	theme	fundamental	246:256	arg1	functions					258:266	The fundamental functions	242:266	The fundamental functions of a wound dressing	242:286	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	7	49	theme	composite	1040:1048	arg1	dressing					1050:1057	PCL membrane composite dressing	1027:1057	PCL membrane composite dressing	1027:1057	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	5	50	contain	had	784:786	arg2	capability					831:840	water-absorbing capability	815:840	water-absorbing capability	815:840	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	5	50	contain	had	784:786	arg2	cytocompatibility					793:809	good cytocompatibility	788:809	good cytocompatibility	788:809	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	5	50	contain	had	784:786	arg1	surface					759:765	the hydrophilic surface	743:765	the hydrophilic surface of the CS sponge	743:782	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	6	51	theme	Insulin-like	843:854	arg1	IGF-2					873:877	IGF-2	873:877	IGF-2	873:877	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	51	theme	Insulin-like	843:854	arg1	factor-2					863:870	Insulin-like growth factor-2	843:870	Insulin-like growth factor-2 (IGF-2)	843:878	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	4	52	theme	composite	491:499	arg1	dressing					501:508	PCL nanofibrous membrane composite dressing	466:508	PCL nanofibrous membrane composite dressing	466:508	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	6	53	from	effect	936:941	arg1	fibroblasts					946:956	fibroblasts migration and proliferation	946:984	fibroblasts migration and proliferation	946:984	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	53	from	effect	936:941	arg1	proliferation					972:984	proliferation	972:984	proliferation	972:984	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	6	53	from	effect	936:941	arg1	migration					958:966	migration	958:966	migration	958:966	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	3	54	from	absorption	300:309	arg1	wound					373:377	the wound	369:377	the wound	369:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	7	55	theme	asymmetric	1143:1152	arg1	wettability					1154:1164	asymmetric wettability	1143:1164	asymmetric wettability	1143:1164	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	7	56	theme	fabricated	1002:1011	arg1	sponge					1016:1021	the fabricated CS sponge	998:1021	the fabricated CS sponge	998:1021	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	4	57	with	sponge	455:460	arg1	surfaces					538:545	asymmetric wettability surfaces	515:545	asymmetric wettability surfaces as wound healing materials	515:572	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	4	58	theme	biomedical	578:587	arg1	applications					589:600	biomedical applications	578:600	biomedical applications	578:600	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
35730493	3	59	theme	wound	273:277	arg1	dressing					279:286	a wound dressing	271:286	a wound dressing	271:286	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	2	60	theme	dressing	232:239	arg1	factors					213:219	the most important factors	194:219	the most important factors of a wound dressing	194:239	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	1	61	theme	wound	132:136	arg1	healing					138:144	wound healing	132:144	wound healing	132:144	An effective dressing is essential for wound healing.					
35730493	7	62	theme	vapor	1092:1096	arg1	rate					1111:1114	vapor transmission rate	1092:1114	vapor transmission rate	1092:1114	Therefore, the fabricated CS sponge and PCL membrane composite dressing had excellent cytocompatibility, vapor transmission rate, and liquid absorption and asymmetric wettability, suggesting its potential as a promising alternative to traditional wound dressing.					
35730493	2	63	theme	wound	226:230	arg1	dressing					232:239	a wound dressing	224:239	a wound dressing	224:239	In fact, the wettability performance is one of the most important factors of a wound dressing.					
35730493	3	64	theme	excess	314:319	arg1	exudates					321:328	excess exudates	314:328	excess exudates	314:328	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	3	65	from	wound	373:377	arg1	maintenance					334:344	maintenance	334:344	maintenance of optimal moisture at the wound	334:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	3	65	from	wound	373:377	arg1	absorption					300:309	the absorption	296:309	the absorption of excess exudates and maintenance of optimal moisture at the wound	296:377	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	3	65	from	wound	373:377	arg1	exudates					321:328	excess exudates	314:328	excess exudates	314:328	The fundamental functions of a wound dressing involve the absorption of excess exudates and maintenance of optimal moisture at the wound by controlling water evaporation.					
35730493	0	66	theme	wettable	14:21	arg1	scaffold					46:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold	0:53	An asymmetric wettable PCL/chitosan composite scaffold loaded with IGF-2 for wound dressing.					
35730493	5	67	theme	good	788:791	arg1	cytocompatibility					793:809	good cytocompatibility	788:809	good cytocompatibility	788:809	The hydrophobic surfaces of the composite dressing were waterproof and could efficiently control the water vapor transmission rate, whereas the hydrophilic surface of the CS sponge had good cytocompatibility and water-absorbing capability.					
35730493	6	68	theme	stimulatory	924:934	arg1	effect					936:941	a stimulatory effect	922:941	a stimulatory effect on fibroblasts migration and proliferation	922:984	Insulin-like growth factor-2 (IGF-2) was added to the CS sponge, and exhibited a stimulatory effect on fibroblasts migration and proliferation.					
35730493	4	69	theme	nanofibrous	470:480	arg1	dressing					501:508	PCL nanofibrous membrane composite dressing	466:508	PCL nanofibrous membrane composite dressing	466:508	Here, we designed a type of chitosan (CS) sponge and PCL nanofibrous membrane composite dressing with asymmetric wettability surfaces as wound healing materials for biomedical applications.					
37282793	0	0	theme	shelf-life	83:92	arg1	extension					94:102	fresh salmon fillet shelf-life extension	63:102	fresh salmon fillet shelf-life extension	63:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	3	1	theme	tree	312:315	arg1	chloride					362:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride	308:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	1	2	theme	products	160:167	arg1	shelf-life					141:150	the shelf-life	137:150	the shelf-life of food products	137:167	Bioactive packaging can improve the shelf-life of food products and enhance consumer health.					
37282793	7	3	theme	tree	791:794	arg1	nanofibers					822:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	0	4	theme	fillet	76:81	arg1	extension					94:102	fresh salmon fillet shelf-life extension	63:102	fresh salmon fillet shelf-life extension	63:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	4	5	theme	contact	567:573	arg1	analysis					587:594	contact angle meter analysis	567:594	contact angle meter analysis	567:594	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	6	theme	total	1014:1018	arg1	nitrogen					1035:1042	total volatile basic nitrogen	1014:1042	total volatile basic nitrogen during storage in the freshness experiments	1014:1086	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	4	7	theme	gravimetric	500:510	arg1	analysis					512:519	thermal gravimetric analysis	492:519	thermal gravimetric analysis	492:519	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	8	theme	oil-loaded	796:805	arg1	nanofibers					822:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	3	9	theme	nanofibers	380:389	arg1	electrospinning					289:303	the electrospinning	285:303	the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	285:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	5	10	theme	well-defined	628:639	arg1	diameter					641:648	a well-defined diameter	626:648	a well-defined diameter of about 200 nm	626:664	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	7	11	theme	volatile	1020:1027	arg1	nitrogen					1035:1042	total volatile basic nitrogen	1014:1042	total volatile basic nitrogen during storage in the freshness experiments	1014:1086	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	4	12	theme	nanofiber	424:432	arg1	films					434:438	The fabricated nanofiber films	409:438	The fabricated nanofiber films	409:438	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	13	theme	texture	943:949	arg1	analysis					951:958	texture analysis	943:958	texture analysis	943:958	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	7	14	theme	sensory	923:929	arg1	evaluation					931:940	sensory evaluation	923:940	sensory evaluation	923:940	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	7	15	theme	Tea	787:789	arg1	nanofibers					822:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	3	16	theme	chloride	362:369	arg1	nanofibers					380:389	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	5	17	theme	smooth	672:677	arg1	shape					679:683	a smooth shape	670:683	a smooth shape	670:683	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	6	18	dep	aureus	749:754	arg1	vitro					780:784	in vitro	777:784	in vitro	777:784	They have good antibacterial properties against Staphylococcus aureus and Escherichia coli in vitro.					
37282793	3	19	theme	chitosan	371:378	arg1	nanofibers					380:389	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	7	20	theme	thiobarbituric	989:1002	arg1	acid					1004:1007	thiobarbituric acid	989:1007	thiobarbituric acid	989:1007	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	7	21	theme	salmon	913:918	arg1	life					905:908	the shelf life	895:908	the shelf life of salmon	895:918	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	1	22	theme	consumer	181:188	arg1	health					190:195	consumer health	181:195	consumer health	181:195	Bioactive packaging can improve the shelf-life of food products and enhance consumer health.					
37282793	3	23	theme	oil-loaded	317:326	arg1	chloride					362:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride	308:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	3	24	theme	2-hydroxypropyltrimethyl	328:351	arg1	chloride					362:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride	308:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	4	25	theme	fabricated	413:422	arg1	films					434:438	The fabricated nanofiber films	409:438	The fabricated nanofiber films	409:438	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	26	from	storage	1051:1057	arg1	experiments					1076:1086	the freshness experiments	1062:1086	the freshness experiments	1062:1086	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	0	27	theme	loading	38:44	arg1	oil					55:57	nanofibers loading tea tree oil	27:57	nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension	27:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	4	28	dep	transform	530:538	arg1	infrared					540:547	infrared	540:547	transform infrared spectroscopy	530:560	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	6	29	contain	have	691:694	arg2	properties					715:724	good antibacterial properties	696:724	good antibacterial properties	696:724	They have good antibacterial properties against Staphylococcus aureus and Escherichia coli in vitro.					
37282793	6	29	contain	have	691:694	arg1	They					686:689	They	686:689	They	686:689	They have good antibacterial properties against Staphylococcus aureus and Escherichia coli in vitro.					
37282793	1	30	theme	Bioactive	105:113	arg1	packaging					115:123	Bioactive packaging	105:123	Bioactive packaging	105:123	Bioactive packaging can improve the shelf-life of food products and enhance consumer health.					
37282793	0	31	theme	nanofibers	27:36	arg1	oil					55:57	nanofibers loading tea tree oil	27:57	nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension	27:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	4	32	dep	Fourier	522:528	arg1	transform					530:538	transform	530:538	transform infrared spectroscopy	530:560	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	33	theme	bioactive	1130:1138	arg1	packaging					1140:1148	bioactive packaging	1130:1148	bioactive packaging	1130:1148	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	4	34	theme	thermal	492:498	arg1	analysis					512:519	thermal gravimetric analysis	492:519	thermal gravimetric analysis	492:519	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	0	35	theme	tree	50:53	arg1	oil					55:57	nanofibers loading tea tree oil	27:57	nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension	27:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	7	36	theme	health	1111:1116	arg1	benefits					1118:1125	their health benefits	1105:1125	their health benefits	1105:1125	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	7	37	theme	shelf	899:903	arg1	life					905:908	the shelf life	895:908	the shelf life of salmon	895:918	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	0	38	theme	tea	46:48	arg1	oil					55:57	nanofibers loading tea tree oil	27:57	nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension	27:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	4	39	theme	meter	581:585	arg1	analysis					587:594	contact angle meter analysis	567:594	contact angle meter analysis	567:594	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	40	theme	freshness	1066:1074	arg1	experiments					1076:1086	the freshness experiments	1062:1086	the freshness experiments	1062:1086	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	4	41	theme	angle	575:579	arg1	analysis					587:594	contact angle meter analysis	567:594	contact angle meter analysis	567:594	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	0	42	theme	fresh	63:67	arg1	extension					94:102	fresh salmon fillet shelf-life extension	63:102	fresh salmon fillet shelf-life extension	63:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	5	43	theme	prepared	601:608	arg1	nanofibers					610:619	The prepared nanofibers	597:619	The prepared nanofibers	597:619	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	5	44	contain	have	621:624	arg1	nanofibers					610:619	The prepared nanofibers	597:619	The prepared nanofibers	597:619	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	5	44	contain	have	621:624	arg2	shape					679:683	a smooth shape	670:683	a smooth shape	670:683	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	5	44	contain	have	621:624	arg2	diameter					641:648	a well-defined diameter	626:648	a well-defined diameter of about 200 nm	626:664	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	3	45	theme	tea	308:310	arg1	chloride					362:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride	308:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	4	46	theme	scanning	462:469	arg1	microscopy					480:489	scanning electron microscopy	462:489	scanning electron microscopy	462:489	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	2	47	theme	environmental	220:232	arg1	stress					234:239	environmental stress	220:239	environmental stress	220:239	It can also alleviate environmental stress on the planet by reducing food waste.					
37282793	7	48	theme	total	968:972	arg1	counts					981:986	total viable counts	968:986	total viable counts	968:986	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	2	49	theme	food	267:270	arg1	waste					272:276	food waste	267:276	food waste	267:276	It can also alleviate environmental stress on the planet by reducing food waste.					
37282793	5	50	theme	200 nm	659:664	arg1	diameter					641:648	a well-defined diameter	626:648	a well-defined diameter of about 200 nm	626:664	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	5	50	theme	200 nm	659:664	arg1	shape					679:683	a smooth shape	670:683	a smooth shape	670:683	The prepared nanofibers have a well-defined diameter of about 200 nm and a smooth shape.					
37282793	6	51	theme	antibacterial	701:713	arg1	properties					715:724	good antibacterial properties	696:724	good antibacterial properties	696:724	They have good antibacterial properties against Staphylococcus aureus and Escherichia coli in vitro.					
37282793	6	52	theme	good	696:699	arg1	properties					715:724	good antibacterial properties	696:724	good antibacterial properties	696:724	They have good antibacterial properties against Staphylococcus aureus and Escherichia coli in vitro.					
37282793	0	53	theme	salmon	69:74	arg1	extension					94:102	fresh salmon fillet shelf-life extension	63:102	fresh salmon fillet shelf-life extension	63:102	Electrospun chitosan-based nanofibers loading tea tree oil for fresh salmon fillet shelf-life extension.					
37282793	4	54	theme	electron	471:478	arg1	microscopy					480:489	scanning electron microscopy	462:489	scanning electron microscopy	462:489	The fabricated nanofiber films were characterized by scanning electron microscopy, thermal gravimetric analysis, Fourier transform infrared spectroscopy, and contact angle meter analysis.					
37282793	7	55	theme	viable	974:979	arg1	counts					981:986	total viable counts	968:986	total viable counts	968:986	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	7	56	theme	chitosan-based	807:820	arg1	nanofibers					822:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers	787:831	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	3	57	theme	ammonium	353:360	arg1	chloride					362:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride	308:369	tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers	308:389	Here, the electrospinning of tea tree oil-loaded 2-hydroxypropyltrimethyl ammonium chloride chitosan nanofibers was investigated.					
37282793	7	58	theme	basic	1029:1033	arg1	nitrogen					1035:1042	total volatile basic nitrogen	1014:1042	total volatile basic nitrogen during storage in the freshness experiments	1014:1086	Tea tree oil-loaded chitosan-based nanofibers were found to be effective in delaying spoilage and extending the shelf life of salmon by sensory evaluation, texture analysis, color, total viable counts, thiobarbituric acid, and total volatile basic nitrogen during storage in the freshness experiments, thus indicating their health benefits in bioactive packaging.					
37282793	1	59	theme	food	155:158	arg1	products					160:167	food products	155:167	food products	155:167	Bioactive packaging can improve the shelf-life of food products and enhance consumer health.					
36876524	0	0	theme	bone	87:90	arg1	repair					92:97	bone repair	87:97	bone repair	87:97	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	3	1	theme	electrostatic	665:677	arg1	interactions					697:708	electrostatic and hydrogen bond interactions	665:708	interactions	697:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	6	2	theme	Gelatin-HAlg-DN	1253:1267	arg1	hydrogels					1269:1277	the Gelatin-HAlg-DN hydrogels	1249:1277	the Gelatin-HAlg-DN hydrogels	1249:1277	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	7	3	theme	size	1450:1453	arg1	model					1467:1471	a rat critical size bone defect model	1435:1471	a rat critical size bone defect model	1435:1471	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	7	4	theme	bone	1455:1458	arg1	model					1467:1471	a rat critical size bone defect model	1435:1471	a rat critical size bone defect model	1435:1471	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	7	5	theme	Gelatin-HAlg-DN	1474:1488	arg1	hydrogels					1490:1498	Gelatin-HAlg-DN hydrogels	1474:1498	Gelatin-HAlg-DN hydrogels loaded with psoralen	1474:1519	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	4	6	theme	carbodiimide	835:846	arg1	hydrochloride					848:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride	801:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC)	801:866	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	4	6	theme	carbodiimide	835:846	arg1	EDC					863:865	EDC	863:865	EDC	863:865	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	1	7	theme	high-strength	149:161	arg1	hydrogels					163:171	high-strength hydrogels	149:171	high-strength hydrogels that are composed entirely of natural polymers	149:218	It has always been a huge challenge to construct high-strength hydrogels that are composed entirely of natural polymers.					
36876524	3	8	theme	due	658:660	arg1	hydrogels					633:641	physically crosslinked hydrogels	610:641	physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions	610:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	3	8	theme	due	658:660	arg1	Gelatin-HAlg					644:655	Gelatin-HAlg	644:655	Gelatin-HAlg	644:655	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	5	9	from	increase	1114:1121	arg1	elongation					1147:1156	elongation	1147:1156	elongation	1147:1156	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	9	from	increase	1114:1121	arg1	strength					1134:1141	tensile strength	1126:1141	tensile strength	1126:1141	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	9	from	increase	1114:1121	arg1	break					1161:1165	break	1161:1165	break	1161:1165	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	10	theme	obtained	940:947	arg1	hydrogels					965:973	The obtained Gelatin-HAlg-DN hydrogels	936:973	The obtained Gelatin-HAlg-DN hydrogels	936:973	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	2	11	dep	gelatin	314:320	arg1	alginate					336:343	alginate	336:343	alginate	336:343	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	12	theme	NP	480:481	arg1	hydrogels					498:506	natural polymer (NP) high-strength hydrogels	463:506	natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN)	463:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	3	13	theme	bond	692:695	arg1	interactions					697:708	electrostatic and hydrogen bond interactions	665:708	interactions	697:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	5	14	theme	Gelatin-HAlg-DN	949:963	arg1	hydrogels					965:973	The obtained Gelatin-HAlg-DN hydrogels	936:973	The obtained Gelatin-HAlg-DN hydrogels	936:973	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	4	15	theme	Gelatin-HAlg	721:732	arg1	hydrogels					734:742	the Gelatin-HAlg hydrogels	717:742	the Gelatin-HAlg hydrogels	717:742	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	7	16	theme	defect	1460:1465	arg1	model					1467:1471	a rat critical size bone defect model	1435:1471	a rat critical size bone defect model	1435:1471	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	4	17	theme	3-dimethylaminopropyl	804:824	arg1	hydrochloride					848:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride	801:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC)	801:866	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	4	17	theme	3-dimethylaminopropyl	804:824	arg1	EDC					863:865	EDC	863:865	EDC	863:865	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	5	18	dep	strength	1036:1043	arg1	%					1079:1079	177%	1076:1079	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	18	dep	strength	1036:1043	arg1	elongation					1055:1064	elongation	1055:1064	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	18	dep	strength	1036:1043	arg1	MPa					1050:1052	0.9 MPa	1046:1052	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	2	19	theme	polymer	471:477	arg1	hydrogels					498:506	natural polymer (NP) high-strength hydrogels	463:506	natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN)	463:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	7	20	theme	critical	1441:1448	arg1	model					1467:1471	a rat critical size bone defect model	1435:1471	a rat critical size bone defect model	1435:1471	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	5	21	from	break	1161:1165	arg1	16-					1097:1099	a maximum 16-	1087:1099	a maximum 16-	1087:1099	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	21	from	break	1161:1165	arg1	increase					1114:1121	3.2-fold increase	1105:1121	3.2-fold increase in tensile strength and elongation at break	1105:1165	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	21	from	break	1161:1165	arg1	strength					1134:1141	tensile strength	1126:1141	tensile strength	1126:1141	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	21	from	break	1161:1165	arg1	elongation					1147:1156	elongation	1147:1156	elongation	1147:1156	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	7	22	theme	appealing	1574:1582	arg1	potential					1584:1592	appealing potential	1574:1592	appealing potential as tissue engineering scaffolds	1574:1624	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	2	23	theme	structural	252:261	arg1	characteristics					263:277	the structural characteristics	248:277	the structural characteristics of the extracellular matrix (ECM)	248:311	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	3	24	theme	hydrogen	683:690	arg1	interactions					697:708	electrostatic and hydrogen bond interactions	665:708	interactions	697:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	4	25	theme	-3-ethyl	826:833	arg1	hydrochloride					848:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride	801:860	1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC)	801:866	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	4	25	theme	-3-ethyl	826:833	arg1	EDC					863:865	EDC	863:865	EDC	863:865	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	6	26	theme	excellent	1287:1295	arg1	biodegradability					1297:1312	excellent biodegradability	1287:1312	excellent biodegradability	1287:1312	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	0	27	theme	Extracellular	0:12	arg1	ECM					22:24	ECM	22:24	ECM	22:24	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	0	27	theme	Extracellular	0:12	arg1	matrix					14:19	Extracellular matrix	0:19	Extracellular matrix (ECM)	0:25	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	6	28	dep	capability	1377:1386	arg1	support					1391:1397	support	1391:1397	to support cell adhesion and proliferation	1388:1429	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	5	29	theme	mechanical	1005:1014	arg1	properties					1016:1025	considerably enhanced mechanical properties	983:1025	considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%)	983:1080	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	6	30	theme	physiological	1343:1355	arg1	conditions					1357:1366	physiological conditions	1343:1366	physiological conditions	1343:1366	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	2	31	theme	matrix	300:305	arg1	characteristics					263:277	the structural characteristics	248:277	the structural characteristics of the extracellular matrix (ECM)	248:311	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	32	theme	glycosaminoglycans	400:417	arg1	composition					372:382	the composition	368:382	the composition of collagen and glycosaminoglycans (GAGs) in the ECM	368:435	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	6	33	theme	cell	1399:1402	arg1	adhesion					1404:1411	cell adhesion	1399:1411	cell adhesion	1399:1411	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	7	34	theme	bone	1547:1550	arg1	regeneration					1552:1563	bone regeneration	1547:1563	bone regeneration	1547:1563	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	2	35	theme	extracellular	286:298	arg1	matrix					300:305	the extracellular matrix	282:305	the extracellular matrix (ECM)	282:311	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	35	theme	extracellular	286:298	arg1	ECM					308:310	ECM	308:310	ECM	308:310	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	5	36	dep	properties	1016:1025	arg1	strength					1036:1043	tensile strength	1028:1043	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	6	37	theme	swelling	1318:1325	arg1	stability					1327:1335	swelling stability	1318:1335	swelling stability	1318:1335	Importantly, the Gelatin-HAlg-DN hydrogels exhibit excellent biodegradability and swelling stability under physiological conditions, and the capability to support cell adhesion and proliferation.					
36876524	1	38	theme	natural	203:209	arg1	polymers					211:218	natural polymers	203:218	natural polymers	203:218	It has always been a huge challenge to construct high-strength hydrogels that are composed entirely of natural polymers.					
36876524	2	39	theme	collagen	387:394	arg1	composition					372:382	the composition	368:382	the composition of collagen and glycosaminoglycans (GAGs) in the ECM	368:435	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	40	theme	high-strength	484:496	arg1	hydrogels					498:506	natural polymer (NP) high-strength hydrogels	463:506	natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN)	463:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	5	41	theme	tensile	1028:1034	arg1	strength					1036:1043	tensile strength	1028:1043	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	42	from	break	1069:1073	arg1	elongation					1055:1064	elongation	1055:1064	tensile strength: 0.9 MPa; elongation at break: 177%	1028:1079	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	0	43	theme	gelatin-alginate	50:65	arg1	hydrogels					73:81	high-strength gelatin-alginate based hydrogels	36:81	high-strength gelatin-alginate based hydrogels for bone repair	36:97	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	0	44	theme	high-strength	36:48	arg1	hydrogels					73:81	high-strength gelatin-alginate based hydrogels	36:81	high-strength gelatin-alginate based hydrogels for bone repair	36:97	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	5	45	theme	tensile	1126:1132	arg1	strength					1134:1141	tensile strength	1126:1141	tensile strength	1126:1141	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	2	46	theme	covalent	536:543	arg1	Gelatin-HAlg-DN					559:573	Gelatin-HAlg-DN	559:573	Gelatin-HAlg-DN	559:573	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	46	theme	covalent	536:543	arg1	interactions					545:556	physical and covalent interactions	523:556	physical and covalent interactions (Gelatin-HAlg-DN)	523:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	47	from	composition	372:382	arg1	ECM					433:435	the ECM	429:435	the ECM	429:435	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	5	48	dep	exhibit	975:981	arg1	compared					1182:1189	compared	1182:1189	compared with gelatin methacrylate (GelMA) hydrogels	1182:1233	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	3	49	link	crosslinked	621:631	arg1	hydrogels					633:641	physically crosslinked hydrogels	610:641	physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions	610:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	3	49	link	crosslinked	621:631	arg1	Gelatin-HAlg					644:655	Gelatin-HAlg	644:655	Gelatin-HAlg	644:655	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	7	50	theme	engineering	1604:1614	arg1	scaffolds					1616:1624	tissue engineering scaffolds	1597:1624	tissue engineering scaffolds	1597:1624	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	2	51	theme	physical	523:530	arg1	Gelatin-HAlg-DN					559:573	Gelatin-HAlg-DN	559:573	Gelatin-HAlg-DN	559:573	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	2	51	theme	physical	523:530	arg1	interactions					545:556	physical and covalent interactions	523:556	physical and covalent interactions (Gelatin-HAlg-DN)	523:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	3	52	theme	crosslinked	621:631	arg1	hydrogels					633:641	physically crosslinked hydrogels	610:641	physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions	610:708	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	3	52	theme	crosslinked	621:631	arg1	Gelatin-HAlg					644:655	Gelatin-HAlg	644:655	Gelatin-HAlg	644:655	First, HAlg and gelatin can form physically crosslinked hydrogels (Gelatin-HAlg) due to electrostatic and hydrogen bond interactions.					
36876524	5	53	theme	enhanced	996:1003	arg1	properties					1016:1025	considerably enhanced mechanical properties	983:1025	considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%)	983:1080	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	1	54	theme	huge	121:124	arg1	It					100:101	It	100:101	It	100:101	It has always been a huge challenge to construct high-strength hydrogels that are composed entirely of natural polymers.					
36876524	1	54	theme	huge	121:124	arg1	challenge					126:134	a huge challenge	119:134	a huge challenge to construct high-strength hydrogels that are composed entirely of natural polymers	119:218	It has always been a huge challenge to construct high-strength hydrogels that are composed entirely of natural polymers.					
36876524	5	55	theme	gelatin	1196:1202	arg1	hydrogels					1225:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	2	56	theme	natural	463:469	arg1	hydrogels					498:506	natural polymer (NP) high-strength hydrogels	463:506	natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN)	463:574	In this study, inspired by the structural characteristics of the extracellular matrix (ECM), gelatin and hydrazide alginate were employed to mimic the composition of collagen and glycosaminoglycans (GAGs) in the ECM, respectively, to develop natural polymer (NP) high-strength hydrogels crosslinked by physical and covalent interactions (Gelatin-HAlg-DN).					
36876524	7	57	theme	rat	1437:1439	arg1	model					1467:1471	a rat critical size bone defect model	1435:1471	a rat critical size bone defect model	1435:1471	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	5	58	theme	3.2-fold	1105:1112	arg1	increase					1114:1121	3.2-fold increase	1105:1121	3.2-fold increase in tensile strength and elongation at break	1105:1165	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	59	from	16-	1097:1099	arg1	elongation					1147:1156	elongation	1147:1156	elongation	1147:1156	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	59	from	16-	1097:1099	arg1	strength					1134:1141	tensile strength	1126:1141	tensile strength	1126:1141	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	59	from	16-	1097:1099	arg1	break					1161:1165	break	1161:1165	break	1161:1165	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	5	60	theme	methacrylate	1204:1215	arg1	hydrogels					1225:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	0	61	theme	based	67:71	arg1	hydrogels					73:81	high-strength gelatin-alginate based hydrogels	36:81	high-strength gelatin-alginate based hydrogels for bone repair	36:97	Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair.					
36876524	5	62	theme	maximum	1089:1095	arg1	16-					1097:1099	a maximum 16-	1087:1099	a maximum 16-	1087:1099	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	7	63	theme	tissue	1597:1602	arg1	scaffolds					1616:1624	tissue engineering scaffolds	1597:1624	tissue engineering scaffolds	1597:1624	In a rat critical size bone defect model, Gelatin-HAlg-DN hydrogels loaded with psoralen could effectively promote bone regeneration, showing appealing potential as tissue engineering scaffolds.					
36876524	4	64	dep	hydrochloride	848:860	arg1	presence					789:796	presence	789:796	presence	789:796	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	4	64	dep	hydrochloride	848:860	arg1	the					785:787	the	785:787	the	785:787	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
36876524	5	65	theme	GelMA	1218:1222	arg1	hydrogels					1225:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	gelatin methacrylate (GelMA) hydrogels	1196:1233	The obtained Gelatin-HAlg-DN hydrogels exhibit considerably enhanced mechanical properties (tensile strength: 0.9 MPa; elongation at break: 177%) with a maximum 16- and 3.2-fold increase in tensile strength and elongation at break, respectively, compared with gelatin methacrylate (GelMA) hydrogels.					
36876524	4	66	theme	Gelatin-HAlg-DN	909:923	arg1	hydrogels					925:933	Gelatin-HAlg-DN hydrogels	909:933	Gelatin-HAlg-DN hydrogels	909:933	Then, the Gelatin-HAlg hydrogels can be further covalently crosslinked in the presence of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to obtain Gelatin-HAlg-DN hydrogels.					
37364953	1	0	from	cucumber	151:158	arg1	FS					138:139	FS	138:139	FS	138:139	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	1	0	from	cucumber	151:158	arg1	sulfate					129:135	Fucan sulfate	123:135	Fucan sulfate (FS) from sea cucumber	123:158	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	3	1	theme	groups	487:492	arg1	sequence					505:512	a novel sequence	497:512	a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain	497:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	1	theme	groups	487:492	arg1	pattern					468:474	a unique distribution pattern	446:474	a unique distribution pattern of sulfate groups	446:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	9	2	theme	potent	1414:1419	arg1	activity					1421:1428	potent activity	1414:1428	potent activity	1414:1428	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	7	3	theme	essential	1223:1231	arg1	pattern					1206:1212	sulfation pattern	1196:1212	sulfation pattern	1196:1212	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	3	theme	essential	1223:1231	arg1	factors					1233:1239	the essential factors	1219:1239	the essential factors for the potent inhibition	1219:1265	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	3	theme	essential	1223:1231	arg1	weight					1185:1190	molecular weight	1175:1190	molecular weight	1175:1190	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	0	4	from	recognition	16:26	arg1	argus					65:69	Bohadschia argus	54:69	Bohadschia argus	54:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	2	5	theme	properties	321:330	arg1	analyses					332:339	physicochemical properties analyses	305:339	physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content	305:415	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	2	5	theme	properties	321:330	arg1	composition					366:376	monosaccharide composition	351:376	monosaccharide composition	351:376	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	2	5	theme	properties	321:330	arg1	weight					389:394	molecular weight	379:394	molecular weight	379:394	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	2	5	theme	properties	321:330	arg1	content					409:415	sulfate content	401:415	sulfate content	401:415	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	6	6	theme	P-selectin	1076:1085	arg1	binding					1087:1093	P-selectin binding	1076:1093	P-selectin binding to PSGL-1 and HL-60 cells	1076:1119	Bioactivity assays showed that BaFSI and BaFSII could potently inhibit P-selectin binding to PSGL-1 and HL-60 cells.					
37364953	5	7	theme	acid	959:962	arg1	hydrolysis					964:973	mild acid hydrolysis	954:973	mild acid hydrolysis	954:973	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	0	8	theme	P-selectin	89:98	arg1	inhibition					75:84	inhibition	75:84	inhibition of P-selectin binding to its ligand	75:120	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	0	8	theme	P-selectin	89:98	arg1	recognition					16:26	Oligomer-guided recognition	0:26	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus	0:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	8	9	with	BaFSII	1302:1307	arg1	weight					1326:1331	a molecular weight	1314:1331	a molecular weight about 15 kDa	1314:1344	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	7	10	theme	potent	1249:1254	arg1	inhibition					1256:1265	the potent inhibition	1245:1265	the potent inhibition	1245:1265	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	3	11	theme	domain	526:531	arg1	A					533:533	domain A	526:533	domain A	526:533	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	8	12	theme	BaFSII	1302:1307	arg1	hydrolysate					1287:1297	an acid hydrolysate	1279:1297	an acid hydrolysate of BaFSII with a molecular weight about 15 kDa	1279:1344	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	8	12	theme	BaFSII	1302:1307	arg1	Meanwhile					1268:1276	Meanwhile	1268:1276	Meanwhile	1268:1276	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	3	13	theme	representative	687:700	arg1	chain					722:726	a representative residual saccharide chain	685:726	a representative residual saccharide chain	685:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	14	theme	unique	448:453	arg1	sequence					505:512	a novel sequence	497:512	a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain	497:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	14	theme	unique	448:453	arg1	pattern					468:474	a unique distribution pattern	446:474	a unique distribution pattern of sulfate groups	446:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	8	15	theme	comparable	1358:1367	arg1	inhibition					1369:1378	a comparable inhibition	1356:1378	a comparable inhibition with the native BaFSII	1356:1401	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	5	16	theme	similar	885:891	arg1	characteristics					904:918	similar structural characteristics	885:918	similar structural characteristics	885:918	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	1	17	theme	sea	147:149	arg1	cucumber					151:158	sea cucumber	147:158	sea cucumber	147:158	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	7	18	theme	sulfation	1196:1204	arg1	pattern					1206:1212	sulfation pattern	1196:1212	sulfation pattern	1196:1212	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	18	theme	sulfation	1196:1204	arg1	factors					1233:1239	the essential factors	1219:1239	the essential factors for the potent inhibition	1219:1265	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	18	theme	sulfation	1196:1204	arg1	weight					1185:1190	molecular weight	1175:1190	molecular weight	1175:1190	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	3	19	theme	oligosaccharides	664:679	arg1	chain					722:726	a representative residual saccharide chain	685:726	a representative residual saccharide chain	685:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	19	theme	oligosaccharides	664:679	arg1	analyses					649:656	the analyses	645:656	the analyses of 12 oligosaccharides	645:679	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	7	20	theme	relationship	1141:1152	arg1	analysis					1154:1161	Structure-activity relationship analysis	1122:1161	Structure-activity relationship analysis	1122:1161	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	2	21	theme	molecular	379:387	arg1	weight					389:394	molecular weight	379:394	molecular weight	379:394	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	7	22	theme	molecular	1175:1183	arg1	pattern					1206:1212	sulfation pattern	1196:1212	sulfation pattern	1196:1212	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	22	theme	molecular	1175:1183	arg1	factors					1233:1239	the essential factors	1219:1239	the essential factors for the potent inhibition	1219:1265	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	7	22	theme	molecular	1175:1183	arg1	weight					1185:1190	molecular weight	1175:1190	molecular weight	1175:1190	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	5	23	theme	FS	866:867	arg1	BaFSIII					839:845	BaFSIII	839:845	BaFSIII	839:845	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	5	23	theme	FS	866:867	arg1	mixture					869:875	a FS mixture	864:875	a FS mixture bearing similar structural characteristics with BaFSI and BaFSII	864:940	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	4	24	theme	depolymerized	816:828	arg1	product					830:836	its peroxide depolymerized product	803:836	its peroxide depolymerized product	803:836	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	3	25	theme	domain	539:544	arg1	B					546:546	domain B	539:546	domain B	539:546	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	6	26	theme	HL-60	1109:1113	arg1	cells					1115:1119	HL-60 cells	1109:1119	HL-60 cells	1109:1119	Bioactivity assays showed that BaFSI and BaFSII could potently inhibit P-selectin binding to PSGL-1 and HL-60 cells.					
37364953	0	27	theme	Oligomer-guided	0:14	arg1	recognition					16:26	Oligomer-guided recognition	0:26	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus	0:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	8	28	theme	molecular	1316:1324	arg1	weight					1326:1331	a molecular weight	1314:1331	a molecular weight about 15 kDa	1314:1344	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	4	29	theme	peroxide	807:814	arg1	product					830:836	its peroxide depolymerized product	803:836	its peroxide depolymerized product	803:836	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	1	30	theme	intriguing	166:175	arg1	structure					177:185	intriguing structure	166:185	intriguing structure	166:185	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	4	31	theme	4-L-Fuc3S-α1	774:785	arg1	structure					763:771	a highly regular structure	746:771	a highly regular structure {4-L-Fuc3S-α1	746:785	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	9	32	theme	regular	1441:1447	arg1	structure					1449:1457	highly regular structure	1434:1457	highly regular structure	1434:1457	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	8	33	theme	native	1389:1394	arg1	BaFSII					1396:1401	the native BaFSII	1385:1401	the native BaFSII	1385:1401	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	5	34	theme	oligosaccharide	979:993	arg1	analysis					995:1002	oligosaccharide analysis	979:1002	oligosaccharide analysis	979:1002	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	3	35	theme	residual	702:709	arg1	chain					722:726	a representative residual saccharide chain	685:726	a representative residual saccharide chain	685:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	36	contain	carry	440:444	arg2	sequence					505:512	a novel sequence	497:512	a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain	497:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	36	contain	carry	440:444	arg1	BaFSI					418:422	BaFSI	418:422	BaFSI	418:422	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	36	contain	carry	440:444	arg2	pattern					468:474	a unique distribution pattern	446:474	a unique distribution pattern of sulfate groups	446:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	37	theme	sulfate	479:485	arg1	groups					487:492	sulfate groups	479:492	sulfate groups	479:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	2	38	theme	sulfate	401:407	arg1	content					409:415	sulfate content	401:415	sulfate content	401:415	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	0	39	theme	sulfate	41:47	arg1	inhibition					75:84	inhibition	75:84	inhibition of P-selectin binding to its ligand	75:120	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	0	39	theme	sulfate	41:47	arg1	recognition					16:26	Oligomer-guided recognition	0:26	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus	0:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	3	40	theme	saccharide	711:720	arg1	chain					722:726	a representative residual saccharide chain	685:726	a representative residual saccharide chain	685:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	0	41	from	inhibition	75:84	arg1	argus					65:69	Bohadschia argus	54:69	Bohadschia argus	54:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	4	42	theme	}	787:787	arg1	n					788:788	}n	787:788	}n	787:788	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	9	43	theme	BaFSII	1462:1467	arg1	activity					1421:1428	potent activity	1414:1428	potent activity	1414:1428	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	9	43	theme	BaFSII	1462:1467	arg1	structure					1449:1457	highly regular structure	1434:1457	highly regular structure	1434:1457	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	1	44	theme	extensive	191:199	arg1	activities					201:210	extensive activities	191:210	extensive activities	191:210	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	0	45	theme	fucan	35:39	arg1	sulfate					41:47	two fucan sulfate	31:47	two fucan sulfate from Bohadschia argus	31:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	8	46	theme	acid	1282:1285	arg1	hydrolysate					1287:1297	an acid hydrolysate	1279:1297	an acid hydrolysate of BaFSII with a molecular weight about 15 kDa	1279:1344	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	8	46	theme	acid	1282:1285	arg1	Meanwhile					1268:1276	Meanwhile	1268:1276	Meanwhile	1268:1276	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	3	47	theme	different	563:571	arg1	residues					578:585	different FucS residues	563:585	different FucS residues	563:585	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	9	48	theme	great	1479:1483	arg1	potential					1485:1493	great potential	1479:1493	great potential for development as a P-selectin inhibitor	1479:1535	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	0	49	from	argus	65:69	arg1	inhibition					75:84	inhibition	75:84	inhibition of P-selectin binding to its ligand	75:120	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	0	49	from	argus	65:69	arg1	sulfate					41:47	two fucan sulfate	31:47	two fucan sulfate from Bohadschia argus	31:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	0	49	from	argus	65:69	arg1	recognition					16:26	Oligomer-guided recognition	0:26	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus	0:69	Oligomer-guided recognition of two fucan sulfate from Bohadschia argus and inhibition of P-selectin binding to its ligand.					
37364953	2	50	theme	physicochemical	305:319	arg1	properties					321:330	physicochemical properties	305:330	physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content	305:415	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	7	51	theme	Structure-activity	1122:1139	arg1	analysis					1154:1161	Structure-activity relationship analysis	1122:1161	Structure-activity relationship analysis	1122:1161	Structure-activity relationship analysis showed that molecular weight and sulfation pattern were the essential factors for the potent inhibition.					
37364953	2	52	dep	obtained	259:266	arg1	followed					291:298	followed	291:298	followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content	291:415	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	4	53	contain	possessed	736:744	arg2	structure					763:771	a highly regular structure	746:771	a highly regular structure {4-L-Fuc3S-α1	746:785	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	4	53	contain	possessed	736:744	arg1	BaFSII					729:734	BaFSII	729:734	BaFSII	729:734	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	5	54	theme	mild	954:957	arg1	hydrolysis					964:973	mild acid hydrolysis	954:973	mild acid hydrolysis	954:973	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	9	55	theme	P-selectin	1516:1525	arg1	inhibitor					1527:1535	a P-selectin inhibitor	1514:1535	a P-selectin inhibitor	1514:1535	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	1	56	theme	Fucan	123:127	arg1	FS					138:139	FS	138:139	FS	138:139	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	1	56	theme	Fucan	123:127	arg1	sulfate					129:135	Fucan sulfate	123:135	Fucan sulfate (FS) from sea cucumber	123:158	Fucan sulfate (FS) from sea cucumber shows intriguing structure and extensive activities.					
37364953	6	57	theme	Bioactivity	1005:1015	arg1	assays					1017:1022	Bioactivity assays	1005:1022	Bioactivity assays	1005:1022	Bioactivity assays showed that BaFSI and BaFSII could potently inhibit P-selectin binding to PSGL-1 and HL-60 cells.					
37364953	8	58	with	inhibition	1369:1378	arg1	BaFSII					1396:1401	the native BaFSII	1385:1401	the native BaFSII	1385:1401	Meanwhile, an acid hydrolysate of BaFSII with a molecular weight about 15 kDa exhibited a comparable inhibition with the native BaFSII.					
37364953	4	59	theme	regular	755:761	arg1	structure					763:771	a highly regular structure	746:771	a highly regular structure {4-L-Fuc3S-α1	746:785	BaFSII possessed a highly regular structure {4-L-Fuc3S-α1,}n according to its peroxide depolymerized product.					
37364953	5	60	theme	structural	893:902	arg1	characteristics					904:918	similar structural characteristics	885:918	similar structural characteristics	885:918	BaFSIII was confirmed as a FS mixture bearing similar structural characteristics with BaFSI and BaFSII by means of mild acid hydrolysis and oligosaccharide analysis.					
37364953	3	61	theme	distribution	455:466	arg1	sequence					505:512	a novel sequence	497:512	a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain	497:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	61	theme	distribution	455:466	arg1	pattern					468:474	a unique distribution pattern	446:474	a unique distribution pattern of sulfate groups	446:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	9	62	dep	activity	1421:1428	arg1	the					1410:1412	the	1410:1412	the	1410:1412	Given the potent activity and highly regular structure of BaFSII, it shows great potential for development as a P-selectin inhibitor.					
37364953	3	63	theme	FucS	573:576	arg1	residues					578:585	different FucS residues	563:585	different FucS residues	563:585	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	2	64	theme	monosaccharide	351:364	arg1	composition					366:376	monosaccharide composition	351:376	monosaccharide composition	351:376	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	2	65	theme	homogeneous	225:235	arg1	FS					237:238	three homogeneous FS	219:238	three homogeneous FS (BaFSI - III)	219:252	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	2	65	theme	homogeneous	225:235	arg1	BaFSI					241:245	BaFSI	241:245	BaFSI	241:245	Here, three homogeneous FS (BaFSI - III) were obtained from Bohadschia argus, followed with physicochemical properties analyses including monosaccharide composition, molecular weight, and sulfate content.					
37364953	3	66	theme	novel	499:503	arg1	sequence					505:512	a novel sequence	497:512	a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain	497:726	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
37364953	3	66	theme	novel	499:503	arg1	pattern					468:474	a unique distribution pattern	446:474	a unique distribution pattern of sulfate groups	446:492	BaFSI was proposed to carry a unique distribution pattern of sulfate groups as a novel sequence composed of domain A and domain B that formed by different FucS residues, markedly differing from FS reported before, according to the analyses of 12 oligosaccharides and a representative residual saccharide chain.					
35648108	1	0	theme	self-assembly	156:168	arg1	process					170:176	the self-assembly process	152:176	the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+	152:242	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	1	1	with	process	170:176	arg1	Zn2+					239:242	Zn2+	239:242	Zn2+	239:242	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	2	2	contain	have	467:470	arg2	pyrenebutyrate/Zn2+					518:536	the amorphous pyrenebutyrate/Zn2+	504:536	the amorphous pyrenebutyrate/Zn2+	504:536	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	2	contain	have	467:470	arg1	microflowers					449:460	well-defined microflowers	436:460	well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+	436:536	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	2	contain	have	467:470	arg2	composition					489:499	exactly the same composition	472:499	exactly the same composition	472:499	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	3	dep	lead	313:316	arg1	whereas					345:351	whereas	345:351	whereas	345:351	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	4	theme	host-guest	377:386	arg1	complex					388:394	the host-guest complex	373:394	the host-guest complex of pyrenebutyrate @ γ-CD	373:419	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	3	5	from	catalyst	678:685	arg1	process					708:714	the self-assembly process	690:714	the self-assembly process	690:714	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	1	6	theme	coordinating	185:196	arg1	pyrenebutyrate					219:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	2	7	theme	amorphous	508:516	arg1	pyrenebutyrate/Zn2+					518:536	the amorphous pyrenebutyrate/Zn2+	504:536	the amorphous pyrenebutyrate/Zn2+	504:536	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	7	theme	amorphous	508:516	arg1	composition					489:499	exactly the same composition	472:499	exactly the same composition	472:499	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	3	8	from	microflowers	636:647	arg1	absence					607:613	the absence	603:613	the absence of γ-CD in the final microflowers	603:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	8	from	microflowers	636:647	arg1	evidence					543:550	The evidence	539:550	The evidence of host-guest formation between 1-PBA and γ-CD	539:597	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	2	9	theme	γ-CD	416:419	arg1	complex					388:394	the host-guest complex	373:394	the host-guest complex of pyrenebutyrate @ γ-CD	373:419	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	10	theme	same	484:487	arg1	pyrenebutyrate/Zn2+					518:536	the amorphous pyrenebutyrate/Zn2+	504:536	the amorphous pyrenebutyrate/Zn2+	504:536	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	10	theme	same	484:487	arg1	composition					489:499	exactly the same composition	472:499	exactly the same composition	472:499	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	2	11	theme	@	414:414	arg1	γ-CD					416:419	pyrenebutyrate @ γ-CD	399:419	pyrenebutyrate @ γ-CD	399:419	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	0	12	theme	Cyclodextrin-catalyzed	0:21	arg1	self-assembly					23:35	Cyclodextrin-catalyzed self-assembly	0:35	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers	0:92	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers.					
35648108	3	13	theme	γ-CD	618:621	arg1	absence					607:613	the absence	603:613	the absence of γ-CD in the final microflowers	603:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	13	theme	γ-CD	618:621	arg1	evidence					543:550	The evidence	539:550	The evidence of host-guest formation between 1-PBA and γ-CD	539:597	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	2	14	theme	pyrenebutyrate	399:412	arg1	γ-CD					416:419	pyrenebutyrate @ γ-CD	399:419	pyrenebutyrate @ γ-CD	399:419	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	3	15	from	evidence	543:550	arg1	microflowers					636:647	the final microflowers	626:647	the final microflowers	626:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	1	16	theme	molecule	210:217	arg1	pyrenebutyrate					219:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	2	17	theme	amorphous	321:329	arg1	precipitates					331:342	amorphous precipitates	321:342	amorphous precipitates	321:342	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	1	18	theme	pyrenebutyrate	219:232	arg1	process					170:176	the self-assembly process	152:176	the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+	152:242	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	0	19	theme	fluorescent	55:65	arg1	molecule					67:74	a coordinating fluorescent molecule	40:74	a coordinating fluorescent molecule	40:74	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers.					
35648108	4	20	theme	dynamic	739:745	arg1	chemistry					758:766	this dynamic host-guest chemistry	734:766	this dynamic host-guest chemistry	734:766	We envision that this dynamic host-guest chemistry would be very promising in creating catassemblies.					
35648108	3	21	theme	final	630:634	arg1	microflowers					636:647	the final microflowers	626:647	the final microflowers	626:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	1	22	theme	fluorescent	198:208	arg1	pyrenebutyrate					219:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	the coordinating fluorescent molecule pyrenebutyrate	181:232	We report that γ-cyclodextrin (γ-CD) is able to catalyze the self-assembly process of the coordinating fluorescent molecule pyrenebutyrate with Zn2+.					
35648108	2	23	theme	well-defined	436:447	arg1	microflowers					449:460	well-defined microflowers	436:460	well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+	436:536	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	0	24	theme	coordinating	42:53	arg1	molecule					67:74	a coordinating fluorescent molecule	40:74	a coordinating fluorescent molecule	40:74	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers.					
35648108	2	25	theme	direct	249:254	arg1	interaction					256:266	The direct interaction	245:266	The direct interaction between pyrenebutyrate and Zn2+	245:298	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	4	26	theme	host-guest	747:756	arg1	chemistry					758:766	this dynamic host-guest chemistry	734:766	this dynamic host-guest chemistry	734:766	We envision that this dynamic host-guest chemistry would be very promising in creating catassemblies.					
35648108	0	27	theme	molecule	67:74	arg1	self-assembly					23:35	Cyclodextrin-catalyzed self-assembly	0:35	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers	0:92	Cyclodextrin-catalyzed self-assembly of a coordinating fluorescent molecule into microflowers.					
35648108	3	28	theme	host-guest	555:564	arg1	formation					566:574	host-guest formation	555:574	host-guest formation between 1-PBA and γ-CD	555:597	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	2	29	theme	Zn2+	365:368	arg1	addition					353:360	addition	353:360	addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD	353:419	The direct interaction between pyrenebutyrate and Zn2+ would simply lead to amorphous precipitates, whereas addition of Zn2+ to the host-guest complex of pyrenebutyrate @ γ-CD would generate well-defined microflowers that have exactly the same composition as the amorphous pyrenebutyrate/Zn2+.					
35648108	3	30	from	absence	607:613	arg1	microflowers					636:647	the final microflowers	626:647	the final microflowers	626:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	31	theme	self-assembly	694:706	arg1	process					708:714	the self-assembly process	690:714	the self-assembly process	690:714	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	32	theme	formation	566:574	arg1	absence					607:613	the absence	603:613	the absence of γ-CD in the final microflowers	603:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	32	theme	formation	566:574	arg1	evidence					543:550	The evidence	539:550	The evidence of host-guest formation between 1-PBA and γ-CD	539:597	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
35648108	3	33	from	γ-CD	618:621	arg1	microflowers					636:647	the final microflowers	626:647	the final microflowers	626:647	The evidence of host-guest formation between 1-PBA and γ-CD and the absence of γ-CD in the final microflowers manifest that γ-CD acts as a catalyst in the self-assembly process.					
36380061	7	0	theme	measurements	1349:1360	arg1	result					1336:1341	The result	1332:1341	The result of ΔE measurements	1332:1360	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	1	theme	prepared	943:950	arg1	composites					963:972	the prepared nano-sized composites	939:972	the prepared nano-sized composites	939:972	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	13	2	theme	cellulose	2396:2404	arg1	index					2387:2391	the crystallinity index	2369:2391	the crystallinity index of cellulose	2369:2404	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	2	3	used	used	407:410	arg2	Nanocomposites					269:282	Nanocomposites	269:282	Nanocomposites	269:282	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	3	used	used	407:410	arg2	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	3	used	used	407:410	arg2	nanofiber					364:372	cellulose nanofiber	354:372	cellulose nanofiber (CNF)	354:378	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	4	theme	silica	298:303	arg1	PVA					345:347	PVA	345:347	PVA	345:347	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	4	theme	silica	298:303	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	13	5	theme	nanocomposite	2447:2459	arg1	use					2430:2432	the use	2426:2432	the use of MPSNP/PVA nanocomposite	2426:2459	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	9	6	theme	treated	1717:1723	arg1	sample					1725:1730	The treated sample	1713:1730	The treated sample with the mentioned material	1713:1758	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	8	7	theme	dyed	1693:1696	arg1	samples					1704:1710	the aged dyed paper samples	1684:1710	the aged dyed paper samples	1684:1710	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	7	8	with	sample	1386:1391	arg1	nanocomposite					1408:1420	MPSNP/PVA nanocomposite	1398:1420	MPSNP/PVA nanocomposite	1398:1420	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	9	theme	atomic	768:773	arg1	microscope					781:790	atomic force microscope	768:790	atomic force microscope	768:790	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	9	theme	atomic	768:773	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	9	10	theme	mentioned	1741:1749	arg1	material					1751:1758	the mentioned material	1737:1758	the mentioned material	1737:1758	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	11	11	theme	stretching	2060:2069	arg1	band					2071:2074	the CH2 stretching band	2052:2074	the CH2 stretching band (refers to the crystallinity of cellulose)	2052:2117	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	4	12	theme	electron	626:633	arg1	microscope					675:684	transmission electron microscope	653:684	transmission electron microscope (TEM)	653:690	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	analysis					718:725	dynamic light scattering analysis	693:725	dynamic light scattering analysis (DLS)	693:731	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	SEM					647:649	SEM	647:649	SEM	647:649	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	Analysis					752:759	X-Ray diffraction Analysis	734:759	X-Ray diffraction Analysis (XRD)	734:765	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	microscope					781:790	atomic force microscope	768:790	atomic force microscope	768:790	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	12	theme	electron	626:633	arg1	AFM					793:795	AFM	793:795	AFM	793:795	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	11	13	with	intensity	2130:2138	arg1	nanocomposite					2177:2189	MPSNP/PVA nanocomposite	2167:2189	MPSNP/PVA nanocomposite	2167:2189	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	17	14	theme	dyed	2950:2953	arg1	manuscripts					2961:2971	the dyed paper manuscripts	2946:2971	the dyed paper manuscripts with madder extract	2946:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	8	15	theme	samples	1704:1710	arg1	treatment					1671:1679	the treatment	1667:1679	the treatment of the aged dyed paper samples	1667:1710	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	16	theme	Mechanical	1549:1558	arg1	elongation					1595:1604	elongation	1595:1604	elongation	1595:1604	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	16	theme	Mechanical	1549:1558	arg1	measurements					1560:1571	Mechanical measurements	1549:1571	Mechanical measurements (tensile strength and elongation)	1549:1605	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	16	theme	Mechanical	1549:1558	arg1	strength					1582:1589	tensile strength	1574:1589	tensile strength	1574:1589	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	7	17	theme	CNF/PVA	1486:1492	arg1	nanocomposite					1494:1506	CNF/PVA nanocomposite	1486:1506	CNF/PVA nanocomposite	1486:1506	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	18	theme	treated	991:997	arg1	samples					1010:1016	the treated dyed paper samples	987:1016	the treated dyed paper samples before and after the aging process	987:1051	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	19	theme	Analysis	577:584	arg1	methods					604:610	Analysis and investigation methods	577:610	methods	604:610	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	17	20	theme	manuscripts	2961:2971	arg1	properties					2932:2941	different properties	2922:2941	different properties of the dyed paper manuscripts with madder extract	2922:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	1	21	used	used	221:224	arg2	composite					193:201	the composite	189:201	the composite cross-linked	189:214	In the present work, the composite cross-linked were used to consolidate the dyed paper manuscripts.					
36380061	4	22	theme	paper	1004:1008	arg1	samples					1010:1016	the treated dyed paper samples	987:1016	the treated dyed paper samples before and after the aging process	987:1051	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	23	theme	investigation	590:602	arg1	methods					604:610	Analysis and investigation methods	577:610	methods	604:610	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	17	24	theme	madder	2978:2983	arg1	extract					2985:2991	madder extract	2978:2991	madder extract	2978:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	15	25	theme	aging	2680:2684	arg1	effect					2650:2655	the effect	2646:2655	the effect of accelerated thermal aging on the cellulosic fibers	2646:2709	Additionally, they reduce the effect of accelerated thermal aging on the cellulosic fibers and give them stability.					
36380061	9	26	theme	strength and	1773:1784	arg1	values					1797:1802	tensile strength and elongation values	1765:1802	tensile strength and elongation values of 84.8 N/nm2 and 1.736%	1765:1827	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	4	27	theme	transmission	653:664	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	27	theme	transmission	653:664	arg1	TEM					687:689	TEM	687:689	TEM	687:689	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	27	theme	transmission	653:664	arg1	microscope					675:684	transmission electron microscope	653:684	transmission electron microscope (TEM)	653:690	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	15	28	theme	accelerated	2660:2670	arg1	aging					2680:2684	accelerated thermal aging	2660:2684	accelerated thermal aging	2660:2684	Additionally, they reduce the effect of accelerated thermal aging on the cellulosic fibers and give them stability.					
36380061	11	29	theme	5	2200:2200	arg1	%					2201:2201	%	2201:2201	%	2201:2201	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	14	30	theme	mechanical	2597:2606	arg1	properties					2608:2617	the mechanical properties	2593:2617	the mechanical properties	2593:2617	This may be due to the nano-mineral particles, which improve the mechanical properties.					
36380061	3	31	dep	concentrations	527:540	arg1	%					543:543	1%	542:543	1%	542:543	Three concentrations 1%, 3%, and 5% have been prepared.					
36380061	3	31	dep	concentrations	527:540	arg1	%					547:547	3%	546:547	3%	546:547	Three concentrations 1%, 3%, and 5% have been prepared.					
36380061	3	31	dep	concentrations	527:540	arg1	%					555:555	5%	554:555	5%	554:555	Three concentrations 1%, 3%, and 5% have been prepared.					
36380061	12	32	theme	measurements	2297:2308	arg1	results					2275:2281	the results	2271:2281	the results of mechanical measurements	2271:2308	The FTIR results supported the results of mechanical measurements.					
36380061	4	33	theme	aging	1039:1043	arg1	process					1045:1051	the aging process	1035:1051	the aging process	1035:1051	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	17	34	theme	different	2922:2930	arg1	properties					2932:2941	different properties	2922:2941	different properties of the dyed paper manuscripts with madder extract	2922:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	16	35	theme	analytical	2761:2770	arg1	methods					2772:2778	analytical methods	2761:2778	analytical methods used for evaluation	2761:2798	The detailed analysis of analytical methods used for evaluation revealed the novelty of MPSNP/PVA nanocomposite, especially at 5%.					
36380061	4	36	used	used	909:912	arg2	methods					604:610	Analysis and investigation methods	577:610	methods	604:610	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	8	37	theme	MPSNP/PVA	1634:1642	arg1	nanocomposite					1644:1656	MPSNP/PVA nanocomposite	1634:1656	MPSNP/PVA nanocomposite	1634:1656	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	7	38	theme	lowest	1437:1442	arg1	5.22					1448:1451	5.22	1448:1451	5.22	1448:1451	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	7	38	theme	lowest	1437:1442	arg1	ΔE					1444:1445	the lowest ΔE	1433:1445	the lowest ΔE (5.22)	1433:1452	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	11	39	theme	control	2228:2234	arg1	sample					2236:2241	the control sample	2224:2241	the control sample	2224:2241	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	8	40	dep	measurements	1560:1571	arg1	elongation					1595:1604	elongation	1595:1604	elongation	1595:1604	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	40	dep	measurements	1560:1571	arg1	measurements					1560:1571	Mechanical measurements	1549:1571	Mechanical measurements (tensile strength and elongation)	1549:1605	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	40	dep	measurements	1560:1571	arg1	strength					1582:1589	tensile strength	1574:1589	tensile strength	1574:1589	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	4	41	theme	light	701:705	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	41	theme	light	701:705	arg1	DLS					728:730	DLS	728:730	DLS	728:730	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	41	theme	light	701:705	arg1	analysis					718:725	dynamic light scattering analysis	693:725	dynamic light scattering analysis (DLS)	693:731	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	0	42	theme	dyed	109:112	arg1	manuscripts					120:130	dyed paper manuscripts	109:130	dyed paper manuscripts with madder	109:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	7	43	theme	highest	1523:1529	arg1	11.66					1541:1545	11.66	1541:1545	11.66	1541:1545	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	7	43	theme	highest	1523:1529	arg1	value					1534:1538	the highest ΔE value	1519:1538	the highest ΔE value (11.66)	1519:1546	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	0	44	dep	study	161:165	arg1	effects					10:16	Potential effects	0:16	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder	0:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	2	45	theme	paper	482:486	arg1	manuscripts					488:498	the dyed paper manuscripts	473:498	the dyed paper manuscripts with madder extract	473:518	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	11	46	theme	treated	2147:2153	arg1	sample					2155:2160	the treated sample	2143:2160	the treated sample	2143:2160	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	5	47	theme	properties	1221:1230	arg1	improvement					1206:1216	the improvement	1202:1216	the improvement of properties of the aged	1202:1242	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	0	48	theme	manuscripts	120:130	arg1	strengthening					92:104	the strengthening	88:104	the strengthening of dyed paper manuscripts with madder	88:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	13	49	theme	CH2	2332:2334	arg1	band					2347:2350	the CH2 stretching band	2328:2350	the CH2 stretching band	2328:2350	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	4	50	dep	microscope	635:644	arg1	transform					807:815	transform	807:815	transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer	807:897	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	0	51	theme	Potential	0:8	arg1	effects					10:16	Potential effects	0:16	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder	0:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	12	52	theme	FTIR	2248:2251	arg1	results					2253:2259	The FTIR results	2244:2259	The FTIR results	2244:2259	The FTIR results supported the results of mechanical measurements.					
36380061	10	53	from	%	1907:1907	arg1	sample					1869:1874	the treated sample	1857:1874	the treated sample with CNF/PVA nanocomposite at 1%	1857:1907	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	9	54	theme	84.8 N/nm2	1807:1816	arg1	values					1797:1802	tensile strength and elongation values	1765:1802	tensile strength and elongation values of 84.8 N/nm2 and 1.736%	1765:1827	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	5	55	theme	surface	1069:1075	arg1	morphology					1077:1086	surface morphology	1069:1086	surface morphology by SEM	1069:1093	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	10	56	theme	lowest	1918:1923	arg1	values					1957:1962	tensile strength and elongation values	1925:1962	values	1957:1962	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	4	57	theme	diffraction	740:750	arg1	XRD					762:764	XRD	762:764	XRD	762:764	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	57	theme	diffraction	740:750	arg1	Analysis					752:759	X-Ray diffraction Analysis	734:759	X-Ray diffraction Analysis (XRD)	734:765	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	57	theme	diffraction	740:750	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	6	58	theme	paper	1290:1294	arg1	fibers					1268:1273	The fibers	1264:1273	The fibers of the treated paper	1264:1294	The fibers of the treated paper became strong and appeared clearly.					
36380061	13	59	theme	stretching	2336:2345	arg1	band					2347:2350	the CH2 stretching band	2328:2350	the CH2 stretching band	2328:2350	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	7	60	theme	MPSNP/PVA	1398:1406	arg1	nanocomposite					1408:1420	MPSNP/PVA nanocomposite	1398:1420	MPSNP/PVA nanocomposite	1398:1420	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	0	61	theme	alcohol	62:68	arg1	nanocomposites					70:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	10	62	theme	CNF/PVA	1881:1887	arg1	nanocomposite					1889:1901	CNF/PVA nanocomposite	1881:1901	CNF/PVA nanocomposite	1881:1901	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	16	63	theme	MPSNP/PVA	2824:2832	arg1	nanocomposite					2834:2846	MPSNP/PVA nanocomposite	2824:2846	MPSNP/PVA nanocomposite	2824:2846	The detailed analysis of analytical methods used for evaluation revealed the novelty of MPSNP/PVA nanocomposite, especially at 5%.					
36380061	17	64	contain	has	2870:2872	arg2	role					2886:2889	a potential role	2874:2889	a potential role	2874:2889	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	17	64	contain	has	2870:2872	arg1	It					2867:2868	It	2867:2868	It	2867:2868	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	16	65	theme	nanocomposite	2834:2846	arg1	novelty					2813:2819	the novelty	2809:2819	the novelty of MPSNP/PVA nanocomposite	2809:2846	The detailed analysis of analytical methods used for evaluation revealed the novelty of MPSNP/PVA nanocomposite, especially at 5%.					
36380061	5	66	theme	MPSNP/PVA	1125:1133	arg1	nanocomposite					1146:1158	MPSNP/PVA core-shell nanocomposite	1125:1158	MPSNP/PVA core-shell nanocomposite	1125:1158	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	6	67	theme	treated	1282:1288	arg1	paper					1290:1294	the treated paper	1278:1294	the treated paper	1278:1294	The fibers of the treated paper became strong and appeared clearly.					
36380061	12	68	theme	mechanical	2286:2295	arg1	measurements					2297:2308	mechanical measurements	2286:2308	mechanical measurements	2286:2308	The FTIR results supported the results of mechanical measurements.					
36380061	2	69	theme	cellulose	354:362	arg1	CNF					375:377	CNF	375:377	CNF	375:377	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	69	theme	cellulose	354:362	arg1	nanofiber					364:372	cellulose nanofiber	354:372	cellulose nanofiber (CNF)	354:378	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	1	70	theme	paper	250:254	arg1	manuscripts					256:266	the dyed paper manuscripts	241:266	the dyed paper manuscripts	241:266	In the present work, the composite cross-linked were used to consolidate the dyed paper manuscripts.					
36380061	7	71	theme	ΔE	1346:1347	arg1	measurements					1349:1360	ΔE measurements	1346:1360	ΔE measurements	1346:1360	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	72	theme	force	775:779	arg1	microscope					781:790	atomic force microscope	768:790	atomic force microscope	768:790	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	72	theme	force	775:779	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	73	theme	nano-sized	952:961	arg1	composites					963:972	the prepared nano-sized composites	939:972	the prepared nano-sized composites	939:972	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	8	74	theme	aged	1688:1691	arg1	samples					1704:1710	the aged dyed paper samples	1684:1710	the aged dyed paper samples	1684:1710	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	2	75	theme	nanoparticle	305:316	arg1	PVA					345:347	PVA	345:347	PVA	345:347	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	75	theme	nanoparticle	305:316	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	13	76	theme	mechanical	2509:2518	arg1	properties					2520:2529	mechanical properties	2509:2529	mechanical properties	2509:2529	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	10	77	theme	tensile strength	1925:1940	arg1	values					1957:1962	tensile strength and elongation values	1925:1962	values	1957:1962	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	8	78	theme	paper	1698:1702	arg1	samples					1704:1710	the aged dyed paper samples	1684:1710	the aged dyed paper samples	1684:1710	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	2	79	theme	mesoporous	287:296	arg1	PVA					345:347	PVA	345:347	PVA	345:347	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	79	theme	mesoporous	287:296	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	1	80	theme	present	175:181	arg1	work					183:186	the present work	171:186	the present work	171:186	In the present work, the composite cross-linked were used to consolidate the dyed paper manuscripts.					
36380061	11	81	theme	CH2	2056:2058	arg1	band					2071:2074	the CH2 stretching band	2052:2074	the CH2 stretching band (refers to the crystallinity of cellulose)	2052:2117	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	0	82	with	manuscripts	120:130	arg1	madder					137:142	madder	137:142	madder	137:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	2	83	theme	/polyvinyl	325:334	arg1	PVA					345:347	PVA	345:347	PVA	345:347	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	83	theme	/polyvinyl	325:334	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	13	84	from	improvement	2494:2504	arg1	properties					2520:2529	mechanical properties	2509:2529	mechanical properties	2509:2529	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	4	85	theme	dyed	999:1002	arg1	samples					1010:1016	the treated dyed paper samples	987:1016	the treated dyed paper samples before and after the aging process	987:1051	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	microscope					675:684	transmission electron microscope	653:684	transmission electron microscope (TEM)	653:690	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	analysis					718:725	dynamic light scattering analysis	693:725	dynamic light scattering analysis (DLS)	693:731	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	SEM					647:649	SEM	647:649	SEM	647:649	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	Analysis					752:759	X-Ray diffraction Analysis	734:759	X-Ray diffraction Analysis (XRD)	734:765	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	microscope					781:790	atomic force microscope	768:790	atomic force microscope	768:790	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	86	theme	scanning	617:624	arg1	AFM					793:795	AFM	793:795	AFM	793:795	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	17	87	theme	paper	2955:2959	arg1	manuscripts					2961:2971	the dyed paper manuscripts	2946:2971	the dyed paper manuscripts with madder extract	2946:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	10	88	with	sample	1869:1874	arg1	nanocomposite					1889:1901	CNF/PVA nanocomposite	1881:1901	CNF/PVA nanocomposite	1881:1901	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	2	89	theme	MPSNP	319:323	arg1	PVA					345:347	PVA	345:347	PVA	345:347	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	89	theme	MPSNP	319:323	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	11	90	theme	sample	2155:2160	arg1	intensity					2130:2138	the intensity	2126:2138	the intensity of the treated sample with MPSNP/PVA nanocomposite	2126:2189	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	14	91	theme	nano-mineral	2555:2566	arg1	particles					2568:2576	the nano-mineral particles	2551:2576	the nano-mineral particles	2551:2576	This may be due to the nano-mineral particles, which improve the mechanical properties.					
36380061	7	92	theme	treated	1466:1472	arg1	sample					1474:1479	the treated sample	1462:1479	the treated sample with CNF/PVA nanocomposite at 5%	1462:1512	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	93	theme	infrared	817:824	arg1	spectroscopy					826:837	infrared spectroscopy	817:837	infrared spectroscopy (FTIR)	817:844	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	93	theme	infrared	817:824	arg1	FTIR					840:843	FTIR	840:843	FTIR	840:843	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	10	94	theme	elongation	1946:1955	arg1	values					1957:1962	tensile strength and elongation values	1925:1962	values	1957:1962	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	0	95	theme	experimental	148:159	arg1	study					161:165	an experimental study	145:165	an experimental study	145:165	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	13	96	theme	MPSNP/PVA	2437:2445	arg1	nanocomposite					2447:2459	MPSNP/PVA nanocomposite	2437:2459	MPSNP/PVA nanocomposite	2437:2459	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	15	97	theme	cellulosic	2693:2702	arg1	fibers					2704:2709	the cellulosic fibers	2689:2709	the cellulosic fibers	2689:2709	Additionally, they reduce the effect of accelerated thermal aging on the cellulosic fibers and give them stability.					
36380061	9	98	theme	tensile	1765:1771	arg1	values					1797:1802	tensile strength and elongation values	1765:1802	tensile strength and elongation values of 84.8 N/nm2 and 1.736%	1765:1827	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	13	99	theme	crystallinity	2373:2385	arg1	index					2387:2391	the crystallinity index	2369:2391	the crystallinity index of cellulose	2369:2404	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	8	100	theme	tensile	1574:1580	arg1	measurements					1560:1571	Mechanical measurements	1549:1571	Mechanical measurements (tensile strength and elongation)	1549:1605	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	8	100	theme	tensile	1574:1580	arg1	strength					1582:1589	tensile strength	1574:1589	tensile strength	1574:1589	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	7	101	from	%	1512:1512	arg1	sample					1474:1479	the treated sample	1462:1479	the treated sample with CNF/PVA nanocomposite at 5%	1462:1512	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	9	102	theme	elongation	1786:1795	arg1	values					1797:1802	tensile strength and elongation values	1765:1802	tensile strength and elongation values of 84.8 N/nm2 and 1.736%	1765:1827	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	15	103	theme	thermal	2672:2678	arg1	aging					2680:2684	accelerated thermal aging	2660:2684	accelerated thermal aging	2660:2684	Additionally, they reduce the effect of accelerated thermal aging on the cellulosic fibers and give them stability.					
36380061	4	104	theme	electron	666:673	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	104	theme	electron	666:673	arg1	TEM					687:689	TEM	687:689	TEM	687:689	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	104	theme	electron	666:673	arg1	microscope					675:684	transmission electron microscope	653:684	transmission electron microscope (TEM)	653:690	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	5	105	theme	consolidation	1173:1185	arg1	process					1187:1193	the consolidation process	1169:1193	the consolidation process	1169:1193	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	13	106	theme	band	2347:2350	arg1	intensity					2315:2323	The intensity	2311:2323	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose,	2311:2405	The intensity of the CH2 stretching band, which refers to the crystallinity index of cellulose, was increased with the use of MPSNP/PVA nanocomposite at 3% and 5%, which explains the improvement in mechanical properties.					
36380061	5	107	theme	nanocomposite	1146:1158	arg1	effectiveness					1108:1120	the effectiveness	1104:1120	the effectiveness of MPSNP/PVA core-shell nanocomposite	1104:1158	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	16	108	theme	methods	2772:2778	arg1	analysis					2749:2756	The detailed analysis	2736:2756	The detailed analysis of analytical methods used for evaluation	2736:2798	The detailed analysis of analytical methods used for evaluation revealed the novelty of MPSNP/PVA nanocomposite, especially at 5%.					
36380061	2	109	theme	consolidation	448:460	arg1	process					462:468	the consolidation process	444:468	the consolidation process of the dyed paper manuscripts with madder extract	444:518	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	0	110	from	effects	10:16	arg1	strengthening					92:104	the strengthening	88:104	the strengthening of dyed paper manuscripts with madder	88:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	17	111	theme	potential	2876:2884	arg1	role					2886:2889	a potential role	2874:2889	a potential role	2874:2889	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	9	112	theme	%	1827:1827	arg1	values					1797:1802	tensile strength and elongation values	1765:1802	tensile strength and elongation values of 84.8 N/nm2 and 1.736%	1765:1827	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	0	113	theme	paper	114:118	arg1	manuscripts					120:130	dyed paper manuscripts	109:130	dyed paper manuscripts with madder	109:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	2	114	theme	manuscripts	488:498	arg1	process					462:468	the consolidation process	444:468	the consolidation process of the dyed paper manuscripts with madder extract	444:518	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	4	115	theme	dynamic	693:699	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	115	theme	dynamic	693:699	arg1	DLS					728:730	DLS	728:730	DLS	728:730	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	115	theme	dynamic	693:699	arg1	analysis					718:725	dynamic light scattering analysis	693:725	dynamic light scattering analysis (DLS)	693:731	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	15	116	from	effect	2650:2655	arg1	fibers					2704:2709	the cellulosic fibers	2689:2709	the cellulosic fibers	2689:2709	Additionally, they reduce the effect of accelerated thermal aging on the cellulosic fibers and give them stability.					
36380061	8	117	theme	nanocomposite	1644:1656	arg1	efficiency					1620:1629	the efficiency	1616:1629	the efficiency of MPSNP/PVA nanocomposite	1616:1656	Mechanical measurements (tensile strength and elongation) revealed the efficiency of MPSNP/PVA nanocomposite at 5% in the treatment of the aged dyed paper samples.					
36380061	7	118	theme	ΔE	1531:1532	arg1	11.66					1541:1545	11.66	1541:1545	11.66	1541:1545	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	7	118	theme	ΔE	1531:1532	arg1	value					1534:1538	the highest ΔE value	1519:1538	the highest ΔE value (11.66)	1519:1546	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	4	119	theme	total	850:854	arg1	ΔE					874:875	ΔE	874:875	ΔE	874:875	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	119	theme	total	850:854	arg1	difference					862:871	total color difference	850:871	total color difference (ΔE)	850:876	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	17	120	with	manuscripts	2961:2971	arg1	extract					2985:2991	madder extract	2978:2991	madder extract	2978:2991	It has a potential role in strengthening and improving different properties of the dyed paper manuscripts with madder extract.					
36380061	4	121	theme	scattering	707:716	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	121	theme	scattering	707:716	arg1	DLS					728:730	DLS	728:730	DLS	728:730	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	121	theme	scattering	707:716	arg1	analysis					718:725	dynamic light scattering analysis	693:725	dynamic light scattering analysis (DLS)	693:731	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	122	theme	color	856:860	arg1	ΔE					874:875	ΔE	874:875	ΔE	874:875	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	122	theme	color	856:860	arg1	difference					862:871	total color difference	850:871	total color difference (ΔE)	850:876	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	7	123	with	sample	1474:1479	arg1	nanocomposite					1494:1506	CNF/PVA nanocomposite	1486:1506	CNF/PVA nanocomposite	1486:1506	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	11	124	theme	MPSNP/PVA	2167:2175	arg1	nanocomposite					2177:2189	MPSNP/PVA nanocomposite	2167:2189	MPSNP/PVA nanocomposite	2167:2189	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	2	125	dep	alcohol	336:342	arg1	/PVA					379:382	/PVA	379:382	/PVA	379:382	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	0	126	theme	nano-cellulose	21:34	arg1	nanocomposites					70:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	7	127	from	%	1426:1426	arg1	sample					1386:1391	the treated sample	1374:1391	the treated sample with MPSNP/PVA nanocomposite at 5%	1374:1426	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	2	128	with	manuscripts	488:498	arg1	madder extract					505:518	madder extract	505:518	madder extract	505:518	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	0	129	theme	nano-silica/polyvinyl	40:60	arg1	nanocomposites					70:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites	21:83	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	5	130	theme	morphology	1077:1086	arg1	results					1058:1064	The results	1054:1064	The results of surface morphology by SEM	1054:1093	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	11	131	theme	cellulose	2108:2116	arg1	crystallinity					2091:2103	the crystallinity	2087:2103	the crystallinity of cellulose	2087:2116	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	11	132	theme	FTIR	2002:2005	arg1	analysis					2007:2014	FTIR analysis	2002:2014	FTIR analysis	2002:2014	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	4	133	theme	X-Ray	734:738	arg1	XRD					762:764	XRD	762:764	XRD	762:764	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	133	theme	X-Ray	734:738	arg1	Analysis					752:759	X-Ray diffraction Analysis	734:759	X-Ray diffraction Analysis (XRD)	734:765	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	4	133	theme	X-Ray	734:738	arg1	microscope					635:644	scanning electron microscope	617:644	scanning electron microscope (SEM)	617:650	Analysis and investigation methods like scanning electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering analysis (DLS), X-Ray diffraction Analysis (XRD), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR) and total color difference (ΔE) by spectrophotometer have been used in order to characterize the prepared nano-sized composites and evaluate the treated dyed paper samples before and after the aging process.					
36380061	2	134	theme	dyed	477:480	arg1	manuscripts					488:498	the dyed paper manuscripts	473:498	the dyed paper manuscripts with madder extract	473:518	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	0	135	theme	nanocomposites	70:83	arg1	effects					10:16	Potential effects	0:16	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder	0:142	Potential effects of nano-cellulose and nano-silica/polyvinyl alcohol nanocomposites in the strengthening of dyed paper manuscripts with madder: an experimental study.					
36380061	9	136	with	sample	1725:1730	arg1	material					1751:1758	the mentioned material	1737:1758	the mentioned material	1737:1758	The treated sample with the mentioned material gave tensile strength and elongation values of 84.8 N/nm2 and 1.736%, respectively.					
36380061	11	137	dep	band	2071:2074	arg1	refers					2077:2082	refers	2077:2082	refers to the crystallinity of cellulose	2077:2116	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	16	138	theme	detailed	2740:2747	arg1	analysis					2749:2756	The detailed analysis	2736:2756	The detailed analysis of analytical methods used for evaluation	2736:2798	The detailed analysis of analytical methods used for evaluation revealed the novelty of MPSNP/PVA nanocomposite, especially at 5%.					
36380061	11	139	theme	%	2201:2201	arg1	increase					2203:2210	a 5% increase	2198:2210	a 5% increase compared to the control sample	2198:2241	FTIR analysis revealed an increase was noticed in the CH2 stretching band (refers to the crystallinity of cellulose), where the intensity of the treated sample with MPSNP/PVA nanocomposite was at a 5% increase compared to the control sample.					
36380061	5	140	theme	aged	1239:1242	arg1	properties					1221:1230	properties	1221:1230	properties of the aged	1221:1242	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	2	141	theme	alcohol	336:342	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	141	theme	alcohol	336:342	arg1	nanofiber					364:372	cellulose nanofiber	354:372	cellulose nanofiber (CNF)	354:378	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	141	theme	alcohol	336:342	arg1	Nanocomposites					269:282	Nanocomposites	269:282	Nanocomposites	269:282	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	7	142	theme	treated	1378:1384	arg1	sample					1386:1391	the treated sample	1374:1391	the treated sample with MPSNP/PVA nanocomposite at 5%	1374:1426	The result of ΔE measurements showed that the treated sample with MPSNP/PVA nanocomposite at 5% gave the lowest ΔE (5.22), while, the treated sample with CNF/PVA nanocomposite at 5% gave the highest ΔE value (11.66).					
36380061	10	143	theme	treated	1861:1867	arg1	sample					1869:1874	the treated sample	1857:1874	the treated sample with CNF/PVA nanocomposite at 1%	1857:1907	In contrast, the treated sample with CNF/PVA nanocomposite at 1% gave the lowest tensile strength and elongation values 38.2 N/nm2, and 1.166%, respectively.					
36380061	1	144	theme	dyed	245:248	arg1	manuscripts					256:266	the dyed paper manuscripts	241:266	the dyed paper manuscripts	241:266	In the present work, the composite cross-linked were used to consolidate the dyed paper manuscripts.					
36380061	5	145	theme	paper	1249:1253	arg1	samples					1255:1261	paper samples	1249:1261	paper samples	1249:1261	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
36380061	2	146	theme	nanofiber	364:372	arg1	alcohol					336:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol	287:342	mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA)	287:348	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	146	theme	nanofiber	364:372	arg1	nanofiber					364:372	cellulose nanofiber	354:372	cellulose nanofiber (CNF)	354:378	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	2	146	theme	nanofiber	364:372	arg1	Nanocomposites					269:282	Nanocomposites	269:282	Nanocomposites	269:282	Nanocomposites of mesoporous silica nanoparticle (MPSNP)/polyvinyl alcohol (PVA) and cellulose nanofiber (CNF)/PVA, which have never been used before, have been evaluated for the consolidation process of the dyed paper manuscripts with madder extract.					
36380061	5	147	theme	core-shell	1135:1144	arg1	nanocomposite					1146:1158	MPSNP/PVA core-shell nanocomposite	1125:1158	MPSNP/PVA core-shell nanocomposite	1125:1158	The results of surface morphology by SEM revealed the effectiveness of MPSNP/PVA core-shell nanocomposite at 5% in the consolidation process, where the improvement of properties of the aged dyed paper samples.					
34978185	0	0	theme	Rapid	122:126	arg1	Sterilization					142:154	Rapid and Efficient Sterilization	122:154	Rapid and Efficient Sterilization	122:154	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	4	1	from	complex	658:664	arg1	substrate					673:681	the substrate	669:681	the substrate	669:681	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	4	2	theme	substrate	742:750	arg1	solubility					724:733	the inherent water solubility	705:733	the inherent water solubility of the substrate	705:750	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	5	3	from	proteins	988:995	arg1	membrane					1009:1016	the cell membrane	1000:1016	the cell membrane	1000:1016	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	2	4	theme	antibacterial	422:434	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	4	theme	antibacterial	422:434	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	0	5	theme	Efficient	132:140	arg1	Sterilization					142:154	Rapid and Efficient Sterilization	122:154	Rapid and Efficient Sterilization	122:154	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	7	6	theme	irradiation	1400:1410	arg1	min					1369:1371	10 min	1366:1371	10 min of 635 + 808 nm dual-light irradiation	1366:1410	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	7	7	dep	irradiation	1400:1410	arg1	nm					1386:1387	nm	1386:1387	nm	1386:1387	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	4	8	theme	photosensitizer/photothermal	786:813	arg1	agent					815:819	the photosensitizer/photothermal agent	782:819	the photosensitizer/photothermal agent	782:819	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	4	9	theme	supramolecular	632:645	arg1	complex					658:664	the supramolecular host-guest complex	628:664	the supramolecular host-guest complex on the substrate	628:681	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	3	10	used	used	495:498	arg2	GO					556:557	GO	556:557	GO	556:557	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	3	10	used	used	495:498	arg2	CN					489:490	CN	489:490	CN	489:490	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	3	10	used	used	495:498	arg2	photosensitizer					505:519	a photosensitizer	503:519	a photosensitizer for photodynamic therapy (PDT)	503:550	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	7	11	theme	E.	1341:1342	arg1	CICC					1349:1352	E. coli CICC 20091	1341:1358	E. coli CICC 20091	1341:1358	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	2	12	theme	oxide	377:381	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	12	theme	oxide	377:381	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	13	theme	nitride	405:411	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	13	theme	nitride	405:411	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	4	14	theme	specific	928:935	arg1	bacteria					937:944	specific bacteria	928:944	specific bacteria	928:944	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	2	15	theme	graphene	368:375	arg1	oxide					377:381	β-cyclodextrin-derivative-functionalized graphene oxide	327:381	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	1	16	theme	phototherapy	218:229	arg1	agents					231:236	phototherapy agents	218:236	phototherapy agents	218:236	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	7	17	theme	excellent	1285:1293	arg1	efficacy					1309:1316	excellent antibacterial efficacy	1285:1316	excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091	1285:1358	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	8	18	theme	cell	1423:1426	arg1	experiments					1442:1452	cell proliferation experiments	1423:1452	cell proliferation experiments	1423:1452	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	2	19	theme	β-cyclodextrin-derivative-functionalized	327:366	arg1	oxide					377:381	β-cyclodextrin-derivative-functionalized graphene oxide	327:381	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	1	20	theme	agents	231:236	arg1	hydrophobicity					200:213	the hydrophobicity	196:213	the hydrophobicity of phototherapy agents	196:236	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	1	20	theme	agents	231:236	arg1	nonselectivity					161:174	The nonselectivity	157:174	The nonselectivity of phototherapy	157:190	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	0	21	theme	Graphene	41:48	arg1	Nitride					73:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	2	22	theme	carbon	398:403	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	22	theme	carbon	398:403	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	4	23	theme	water	718:722	arg1	solubility					724:733	the inherent water solubility	705:733	the inherent water solubility of the substrate	705:750	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	0	24	theme	β-Cyclodextrin-Derivative-Functionalized	0:39	arg1	Nitride					73:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	2	25	theme	/graphitic	387:396	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	25	theme	/graphitic	387:396	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	8	26	theme	proliferation	1428:1440	arg1	experiments					1442:1452	cell proliferation experiments	1423:1452	cell proliferation experiments	1423:1452	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	4	27	theme	inherent	709:716	arg1	solubility					724:733	the inherent water solubility	705:733	the inherent water solubility of the substrate	705:750	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	0	28	theme	Carbon	66:71	arg1	Nitride					73:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	4	29	theme	agent	815:819	arg1	aggregation					767:777	the aggregation	763:777	the aggregation of the photosensitizer/photothermal agent	763:819	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	0	30	theme	Oxide/Graphitic	50:64	arg1	Nitride					73:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride	0:79	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	5	31	theme	reactive	1028:1035	arg1	ROS					1053:1055	ROS	1053:1055	ROS	1053:1055	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	5	31	theme	reactive	1028:1035	arg1	species					1044:1050	reactive oxygen species	1028:1050	reactive oxygen species (ROS)	1028:1056	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	2	32	dep	oxide	377:381	arg1	GO					384:385	GO	384:385	GO	384:385	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	6	33	dep	Escherichia	1126:1136	arg1	coli					1138:1141	coli	1138:1141	coli	1138:1141	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	8	34	contain	has	1487:1489	arg1	material					1478:1485	the composite material	1464:1485	the composite material	1464:1485	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	8	34	contain	has	1487:1489	arg2	biocompatibility					1496:1511	good biocompatibility	1491:1511	good biocompatibility	1491:1511	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	5	35	theme	cell	1004:1007	arg1	membrane					1009:1016	the cell membrane	1000:1016	the cell membrane	1000:1016	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	7	36	theme	coli	1344:1347	arg1	CICC					1349:1352	E. coli CICC 20091	1341:1358	E. coli CICC 20091	1341:1358	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	7	37	dep	nm	1386:1387	arg1	808					1382:1384	808	1382:1384	808	1382:1384	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	7	37	dep	nm	1386:1387	arg1	635					1376:1378	635	1376:1378	635	1376:1378	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	6	38	theme	Escherichia	1126:1136	arg1	20091					1148:1152	Escherichia coli CICC 20091	1126:1152	Escherichia coli CICC 20091	1126:1152	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	6	39	theme	specific	1106:1113	arg1	capture					1115:1121	The specific capture	1102:1121	The specific capture of Escherichia coli CICC 20091 by mannose	1102:1163	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	6	40	theme	20091	1148:1152	arg1	capture					1115:1121	The specific capture	1102:1121	The specific capture of Escherichia coli CICC 20091 by mannose	1102:1163	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	8	41	theme	bacterial	1547:1555	arg1	infections					1557:1566	bacterial infections	1547:1566	bacterial infections	1547:1566	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	8	42	theme	composite	1468:1476	arg1	material					1478:1485	the composite material	1464:1485	the composite material	1464:1485	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	3	43	theme	photodynamic	525:536	arg1	PDT					547:549	PDT	547:549	PDT	547:549	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	3	43	theme	photodynamic	525:536	arg1	therapy					538:544	photodynamic therapy	525:544	photodynamic therapy (PDT)	525:550	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	7	44	theme	antibacterial	1295:1307	arg1	efficacy					1309:1316	excellent antibacterial efficacy	1285:1316	excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091	1285:1358	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	7	45	theme	%	1331:1331	arg1	efficacy					1309:1316	excellent antibacterial efficacy	1285:1316	excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091	1285:1358	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	4	46	dep	can	683:685	arg1	only					691:694	only	691:694	only	691:694	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	4	47	theme	host-guest	647:656	arg1	complex					658:664	the supramolecular host-guest complex	628:664	the supramolecular host-guest complex on the substrate	628:681	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	8	48	theme	good	1491:1494	arg1	biocompatibility					1496:1511	good biocompatibility	1491:1511	good biocompatibility	1491:1511	Moreover, cell proliferation experiments show that the composite material has good biocompatibility, expected to have applications in bacterial infections.					
34978185	7	49	theme	dual-light	1389:1398	arg1	irradiation					1400:1410	635 + 808 nm dual-light irradiation	1376:1410	635 + 808 nm dual-light irradiation	1376:1410	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	6	50	theme	side	1229:1232	arg1	effects					1234:1240	side effects	1229:1240	side effects	1229:1240	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	1	51	from	application	250:260	arg1	treatment					269:277	the treatment	265:277	the treatment of antibiotic-resistant bacteria	265:310	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	2	52	theme	g-C3N4	414:419	arg1	materials					436:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials	327:444	β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN)	327:456	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	2	52	theme	g-C3N4	414:419	arg1	CDM/GO/CN					447:455	CDM/GO/CN	447:455	CDM/GO/CN	447:455	In this work, β-cyclodextrin-derivative-functionalized graphene oxide (GO)/graphitic carbon nitride (g-C3N4) antibacterial materials (CDM/GO/CN) were designed and synthesized.					
34978185	6	53	theme	sterilization	1192:1204	arg1	efficiency					1206:1215	the sterilization efficiency	1188:1215	the sterilization efficiency	1188:1215	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	5	54	theme	oxygen	1037:1042	arg1	ROS					1053:1055	ROS	1053:1055	ROS	1053:1055	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	5	54	theme	oxygen	1037:1042	arg1	species					1044:1050	reactive oxygen species	1028:1050	reactive oxygen species (ROS)	1028:1056	The hyperthermia caused by PTT denatures proteins on the cell membrane, allowing reactive oxygen species (ROS) to enter the cell better and kill bacteria.					
34978185	3	55	theme	photothermal	587:598	arg1	therapy					600:606	photothermal therapy	587:606	photothermal therapy (PTT)	587:612	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	3	55	theme	photothermal	587:598	arg1	PTT					609:611	PTT	609:611	PTT	609:611	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	1	56	theme	phototherapy	179:190	arg1	hydrophobicity					200:213	the hydrophobicity	196:213	the hydrophobicity of phototherapy agents	196:236	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	1	56	theme	phototherapy	179:190	arg1	nonselectivity					161:174	The nonselectivity	157:174	The nonselectivity of phototherapy	157:190	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	1	57	theme	antibiotic-resistant	282:301	arg1	bacteria					303:310	antibiotic-resistant bacteria	282:310	antibiotic-resistant bacteria	282:310	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	4	58	theme	photosensitizer/photothermal	869:896	arg1	agent					898:902	the photosensitizer/photothermal agent	865:902	the photosensitizer/photothermal agent	865:902	In addition, the supramolecular host-guest complex on the substrate can not only increase the inherent water solubility of the substrate and reduce the aggregation of the photosensitizer/photothermal agent but also manipulate the interaction between the photosensitizer/photothermal agent and bacteria to capture specific bacteria.					
34978185	3	59	theme	photothermal	564:575	arg1	agent					577:581	a photothermal agent	562:581	a photothermal agent for photothermal therapy (PTT)	562:612	CN is used as a photosensitizer for photodynamic therapy (PDT) and GO as a photothermal agent for photothermal therapy (PTT).					
34978185	6	60	theme	CICC	1143:1146	arg1	20091					1148:1152	Escherichia coli CICC 20091	1126:1152	Escherichia coli CICC 20091	1126:1152	The specific capture of Escherichia coli CICC 20091 by mannose significantly improves the sterilization efficiency and reduces side effects.					
34978185	1	61	theme	bacteria	303:310	arg1	treatment					269:277	the treatment	265:277	the treatment of antibiotic-resistant bacteria	265:310	The nonselectivity of phototherapy and the hydrophobicity of phototherapy agents limit their application in the treatment of antibiotic-resistant bacteria.					
34978185	0	62	theme	Synergistic	99:109	arg1	Effect					111:116	a Synergistic Effect	97:116	a Synergistic Effect for Rapid and Efficient Sterilization	97:154	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	7	63	theme	synergistic	1247:1257	arg1	agent					1273:1277	The synergistic antibacterial agent	1243:1277	The synergistic antibacterial agent	1243:1277	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
34978185	0	64	with	Composites	81:90	arg1	Effect					111:116	a Synergistic Effect	97:116	a Synergistic Effect for Rapid and Efficient Sterilization	97:154	β-Cyclodextrin-Derivative-Functionalized Graphene Oxide/Graphitic Carbon Nitride Composites with a Synergistic Effect for Rapid and Efficient Sterilization.					
34978185	7	65	theme	antibacterial	1259:1271	arg1	agent					1273:1277	The synergistic antibacterial agent	1243:1277	The synergistic antibacterial agent	1243:1277	The synergistic antibacterial agent shows excellent antibacterial efficacy of over 99.25% against E. coli CICC 20091 after 10 min of 635 + 808 nm dual-light irradiation.					
36682651	5	0	theme	film	635:638	arg1	angle					604:608	the water contact angle	586:608	the water contact angle of regenerated-cellulose film from 53.8° to 83.8°	586:658	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	6	1	theme	UV-blocking	701:711	arg1	properties					713:722	UV-blocking properties	701:722	UV-blocking properties	701:722	Moreover, the composite films exhibited UV-blocking properties while maintaining adequate transparency.					
36682651	9	2	theme	hydrophilia	1128:1138	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	3	theme	delayed	1195:1201	arg1	biodegradation					1203:1216	delayed biodegradation	1195:1216	delayed biodegradation	1195:1216	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	4	theme	biodegradation	1203:1216	arg1	performances					1218:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	5	theme	film	1092:1095	arg1	performances					1218:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	6	from	sensor	1275:1280	arg1	packaging					1290:1298	food packaging	1285:1298	food packaging	1285:1298	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	2	7	theme	seed	305:308	arg1	extract					310:316	the grape seed extract	295:316	the grape seed extract	295:316	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	3	8	with	compatibility	398:410	arg1	matrix					434:439	cellulose matrix	424:439	cellulose matrix	424:439	FTIR and SEM techniques were employed to prove the compatibility of GSE with cellulose matrix.					
36682651	2	9	theme	grape	299:303	arg1	extract					310:316	the grape seed extract	295:316	the grape seed extract	295:316	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	9	10	theme	regenerated	1070:1080	arg1	film					1092:1095	a regenerated cellulose film	1068:1095	a regenerated cellulose film with acceptable mechanical and hydrophilia properties	1068:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	3	11	theme	SEM	356:358	arg1	techniques					360:369	FTIR and SEM techniques	347:369	FTIR and SEM techniques	347:369	FTIR and SEM techniques were employed to prove the compatibility of GSE with cellulose matrix.					
36682651	5	12	theme	contact	596:602	arg1	angle					604:608	the water contact angle	586:608	the water contact angle of regenerated-cellulose film from 53.8° to 83.8°	586:658	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	5	13	theme	water	590:594	arg1	angle					604:608	the water contact angle	586:608	the water contact angle of regenerated-cellulose film from 53.8° to 83.8°	586:658	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	1	14	theme	Eco-friendly	78:89	arg1	requirement					163:173	a requirement	161:173	a requirement for food safety and quality	161:201	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	1	14	theme	Eco-friendly	78:89	arg1	material					101:108	Eco-friendly packaging material	78:108	Eco-friendly packaging material with intelligent colorimetric performance	78:150	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	9	15	theme	cellulose	1082:1090	arg1	film					1092:1095	a regenerated cellulose film	1068:1095	a regenerated cellulose film with acceptable mechanical and hydrophilia properties	1068:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	0	16	theme	grape	58:62	arg1	extract					69:75	grape seed extract	58:75	grape seed extract	58:75	Performance-enhanced regenerated cellulose film by adding grape seed extract.					
36682651	9	17	with	pH-responsiveness	1152:1168	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	1	18	theme	packaging	91:99	arg1	requirement					163:173	a requirement	161:173	a requirement for food safety and quality	161:201	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	1	18	theme	packaging	91:99	arg1	material					101:108	Eco-friendly packaging material	78:108	Eco-friendly packaging material with intelligent colorimetric performance	78:150	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	6	19	theme	composite	675:683	arg1	films					685:689	the composite films	671:689	the composite films	671:689	Moreover, the composite films exhibited UV-blocking properties while maintaining adequate transparency.					
36682651	5	20	dep	83.8°	654:658	arg1	to					651:652	to	651:652	to	651:652	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	5	21	theme	PEG	560:562	arg1	addition					548:555	The addition	544:555	The addition of PEG and GSE	544:570	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	1	22	dep	food	179:182	arg1	quality					195:201	quality	195:201	quality	195:201	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	1	22	dep	food	179:182	arg1	safety					184:189	safety	184:189	safety	184:189	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	7	23	theme	pH	854:855	arg1	conditions					857:866	different pH conditions	844:866	different pH conditions	844:866	The GSE induced the regenerated films with a macroscopic change in color under different pH conditions.					
36682651	9	24	with	film	1092:1095	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	5	25	theme	regenerated-cellulose	613:633	arg1	film					635:638	regenerated-cellulose film	613:638	regenerated-cellulose film	613:638	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	2	26	theme	polyethylene	322:333	arg1	glycol					335:340	polyethylene glycol 200	322:344	polyethylene glycol 200	322:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	8	27	theme	GSE	897:899	arg1	loading					886:892	the loading	882:892	the loading of GSE	882:899	Furthermore, the loading of GSE slowed down the decomposition of strawberries and delayed the self-biodegradation compared with the control for more than 3 days and 18 days.					
36682651	1	28	with	material	101:108	arg1	performance					140:150	intelligent colorimetric performance	115:150	intelligent colorimetric performance	115:150	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	7	29	theme	macroscopic	810:820	arg1	change					822:827	a macroscopic change	808:827	a macroscopic change in color	808:836	The GSE induced the regenerated films with a macroscopic change in color under different pH conditions.					
36682651	5	30	theme	GSE	568:570	arg1	addition					548:555	The addition	544:555	The addition of PEG and GSE	544:570	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	1	31	theme	intelligent	115:125	arg1	performance					140:150	intelligent colorimetric performance	115:150	intelligent colorimetric performance	115:150	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	9	32	theme	mechanical	1113:1122	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	0	33	theme	cellulose	33:41	arg1	film					43:46	cellulose film	33:46	cellulose film	33:46	Performance-enhanced regenerated cellulose film by adding grape seed extract.					
36682651	9	34	theme	pH-responsiveness	1152:1168	arg1	performances					1218:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	35	theme	potential	1259:1267	arg1	sensor					1275:1280	a potential color sensor	1257:1280	a potential color sensor in food packaging	1257:1298	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	1	36	theme	colorimetric	127:138	arg1	performance					140:150	intelligent colorimetric performance	115:150	intelligent colorimetric performance	115:150	Eco-friendly packaging material with intelligent colorimetric performance has been a requirement for food safety and quality.					
36682651	9	37	theme	acceptable	1102:1111	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	38	theme	color	1269:1273	arg1	sensor					1275:1280	a potential color sensor	1257:1280	a potential color sensor in food packaging	1257:1298	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	7	39	from	change	822:827	arg1	color					832:836	color	832:836	color	832:836	The GSE induced the regenerated films with a macroscopic change in color under different pH conditions.					
36682651	2	40	from	films	278:282	arg1	material					242:249	a food packaging material	225:249	a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200	225:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	3	41	theme	cellulose	424:432	arg1	matrix					434:439	cellulose matrix	424:439	cellulose matrix	424:439	FTIR and SEM techniques were employed to prove the compatibility of GSE with cellulose matrix.					
36682651	4	42	theme	enhanced	471:478	arg1	elongation					480:489	an enhanced elongation	468:489	an enhanced elongation	468:489	The composite film showed an enhanced elongation at break (16.61 %) and tensile strength (33.09 MPa).					
36682651	9	43	with	anti-decomposition	1171:1188	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	0	44	theme	seed	64:67	arg1	extract					69:75	grape seed extract	58:75	grape seed extract	58:75	Performance-enhanced regenerated cellulose film by adding grape seed extract.					
36682651	4	45	theme	tensile	514:520	arg1	33.09 MPa					532:540	33.09 MPa	532:540	33.09 MPa	532:540	The composite film showed an enhanced elongation at break (16.61 %) and tensile strength (33.09 MPa).					
36682651	4	45	theme	tensile	514:520	arg1	strength					522:529	tensile strength	514:529	tensile strength (33.09 MPa)	514:541	The composite film showed an enhanced elongation at break (16.61 %) and tensile strength (33.09 MPa).					
36682651	2	46	theme	packaging	232:240	arg1	material					242:249	a food packaging material	225:249	a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200	225:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	3	47	theme	GSE	415:417	arg1	compatibility					398:410	the compatibility	394:410	the compatibility of GSE with cellulose matrix	394:439	FTIR and SEM techniques were employed to prove the compatibility of GSE with cellulose matrix.					
36682651	9	48	with	biodegradation	1203:1216	arg1	properties					1140:1149	acceptable mechanical and hydrophilia properties	1102:1149	acceptable mechanical and hydrophilia properties	1102:1149	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	9	49	theme	food	1285:1288	arg1	packaging					1290:1298	food packaging	1285:1298	food packaging	1285:1298	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	2	50	theme	food	227:230	arg1	material					242:249	a food packaging material	225:249	a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200	225:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	8	51	theme	strawberries	934:945	arg1	decomposition					917:929	the decomposition	913:929	the decomposition of strawberries	913:945	Furthermore, the loading of GSE slowed down the decomposition of strawberries and delayed the self-biodegradation compared with the control for more than 3 days and 18 days.					
36682651	6	52	theme	adequate	742:749	arg1	transparency					751:762	adequate transparency	742:762	adequate transparency	742:762	Moreover, the composite films exhibited UV-blocking properties while maintaining adequate transparency.					
36682651	4	53	theme	composite	446:454	arg1	film					456:459	The composite film	442:459	The composite film	442:459	The composite film showed an enhanced elongation at break (16.61 %) and tensile strength (33.09 MPa).					
36682651	9	54	theme	anti-decomposition	1171:1188	arg1	performances					1218:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances	1068:1229	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	7	55	theme	different	844:852	arg1	conditions					857:866	different pH conditions	844:866	different pH conditions	844:866	The GSE induced the regenerated films with a macroscopic change in color under different pH conditions.					
36682651	3	56	theme	FTIR	347:350	arg1	techniques					360:369	FTIR and SEM techniques	347:369	FTIR and SEM techniques	347:369	FTIR and SEM techniques were employed to prove the compatibility of GSE with cellulose matrix.					
36682651	2	57	theme	cellulose	268:276	arg1	films					278:282	regenerated cellulose films	256:282	regenerated cellulose films that added the grape seed extract and polyethylene glycol 200	256:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	5	58	from	83.8°	654:658	arg1	angle					604:608	the water contact angle	586:608	the water contact angle of regenerated-cellulose film from 53.8° to 83.8°	586:658	The addition of PEG and GSE also improved the water contact angle of regenerated-cellulose film from 53.8° to 83.8°.					
36682651	2	59	theme	regenerated	256:266	arg1	films					278:282	regenerated cellulose films	256:282	regenerated cellulose films that added the grape seed extract and polyethylene glycol 200	256:344	This work focused on a food packaging material from regenerated cellulose films that added the grape seed extract and polyethylene glycol 200.					
36682651	9	60	theme	present	1047:1053	arg1	study					1055:1059	The present study	1043:1059	The present study	1043:1059	The present study showed a regenerated cellulose film with acceptable mechanical and hydrophilia properties, pH-responsiveness, anti-decomposition, and delayed biodegradation performances by adding GSE, indicating a potential color sensor in food packaging.					
36682651	7	61	theme	regenerated	785:795	arg1	films					797:801	the regenerated films	781:801	the regenerated films	781:801	The GSE induced the regenerated films with a macroscopic change in color under different pH conditions.					
35324697	6	0	theme	flint	823:827	arg1	subpopulation					835:847	the flint maize subpopulation	819:847	the flint maize subpopulation	819:847	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	9	1	theme	contamination	1405:1417	arg1	risk					1376:1379	the risk	1372:1379	the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol)	1372:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	8	2	theme	IFER	1172:1175	arg1	content					1190:1196	(IFER) and amylose content	1171:1196	content	1190:1196	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	7	3	dep	beauvericin	1068:1078	arg1	value					1087:1091	the R value	1081:1091	the R value ranged from 0.364 in 2015 to 0.785 in 2017	1081:1134	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	4	theme	R	979:979	arg1	value					981:985	the R value	975:985	the R value ranged from 0.396 in 2015 to 0.735 in 2018	975:1028	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	8	5	theme	Fusarium	1319:1326	arg1	rot					1332:1334	Fusarium ear rot	1319:1334	Fusarium ear rot	1319:1334	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	6	6	contain	contained	642:650	arg2	amylose					671:677	significantly less amylose	652:677	significantly less amylose	652:677	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	6	contain	contained	642:650	arg1	kernels					634:640	The dent-type kernels	620:640	The dent-type kernels	620:640	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	7	7	theme	significant	872:882	arg1	correlation					893:903	a significant positive correlation	870:903	a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017)	870:1135	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	5	8	located	found	584:588	arg1	studies					518:524	inoculation studies	506:524	inoculation studies	506:524	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	5	8	located	found	584:588	arg2	variation					539:547	substantial variation	527:547	substantial variation of host response to the fungus	527:578	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	7	9	theme	beauvericin	1068:1078	arg1	IFER					1043:1046	IFER	1043:1046	IFER	1043:1046	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	9	theme	beauvericin	1068:1078	arg1	presence					1056:1063	the presence	1052:1063	the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017)	1052:1135	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	0	10	from	Influence	0:8	arg1	Response					51:58	Maize Response	45:58	Maize Response to Fusarium temperatum Scaufl	45:88	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.					
35324697	3	11	theme	species	201:207	arg1	FFSC					218:221	FFSC	218:221	FFSC	218:221	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	11	theme	species	201:207	arg1	complex					209:215	species complex	201:215	species complex (FFSC)	201:222	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	5	12	theme	host	552:555	arg1	response					557:564	host response	552:564	host response to the fungus	552:578	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	9	13	theme	conducted	1341:1349	arg1	study					1351:1355	The conducted study	1337:1355	The conducted study	1337:1355	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	3	14	dep	fujikuroi	191:199	arg1	FFSC					218:221	FFSC	218:221	FFSC	218:221	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	14	dep	fujikuroi	191:199	arg1	complex					209:215	species complex	201:215	species complex (FFSC)	201:222	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	9	15	theme	kernel	1384:1389	arg1	infection					1391:1399	kernel infection	1384:1399	kernel infection	1384:1399	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	5	16	theme	maize	607:611	arg1	types					613:617	the tested maize types	596:617	the tested maize types	596:617	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	5	17	theme	response	557:564	arg1	variation					539:547	substantial variation	527:547	substantial variation of host response to the fungus	527:578	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	6	18	theme	higher	716:721	arg1	rates					723:727	significantly higher rates	702:727	significantly higher rates of infection (IFER = 2.10)	702:754	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	19	theme	less	666:669	arg1	amylose					671:677	significantly less amylose	652:677	significantly less amylose	652:677	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	9	20	with	infection	1391:1399	arg1	metabolites					1431:1441	fungal metabolites	1424:1441	fungal metabolites (beauvericin and ergosterol)	1424:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	20	with	infection	1391:1399	arg1	ergosterol					1460:1469	ergosterol	1460:1469	ergosterol	1460:1469	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	20	with	infection	1391:1399	arg1	beauvericin					1444:1454	beauvericin	1444:1454	beauvericin	1444:1454	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	8	21	theme	ear	1328:1330	arg1	rot					1332:1334	Fusarium ear rot	1319:1334	Fusarium ear rot	1319:1334	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	3	22	theme	described	149:157	arg1	taxon					159:163	a newly described taxon	141:163	a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot	141:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	22	theme	described	149:157	arg1	Munaut					131:136	Munaut	131:136	Munaut	131:136	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	23	theme	frequent	230:237	arg1	factor					249:254	a frequent causative factor	228:254	a frequent causative factor of maize ear rot	228:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	24	theme	Fusarium	182:189	arg1	fujikuroi					191:199	the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot	178:271	fujikuroi	191:199	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	7	25	dep	0.785	1122:1126	arg1	to					1119:1120	to	1119:1120	to	1119:1120	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	26	theme	positive	884:891	arg1	correlation					893:903	a significant positive correlation	870:903	a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017)	870:1135	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	27	theme	R	1085:1085	arg1	value					1087:1091	the R value	1081:1091	the R value ranged from 0.364 in 2015 to 0.785 in 2017	1081:1134	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	6	28	theme	=	748:748	arg1	infection					732:740	infection	732:740	infection (IFER = 2.10)	732:754	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	28	theme	=	748:748	arg1	2.10					750:753	IFER = 2.10	743:753	IFER = 2.10	743:753	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	9	29	theme	maize	1496:1500	arg1	kernels					1507:1513	the maize type kernels	1492:1513	the maize type kernels	1492:1513	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	5	30	theme	substantial	527:537	arg1	variation					539:547	substantial variation	527:547	substantial variation of host response to the fungus	527:578	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	6	31	theme	dent-type	624:632	arg1	kernels					634:640	The dent-type kernels	620:640	The dent-type kernels	620:640	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	32	dep	contained	642:650	arg1	%					685:685	28.27%	680:685	28.27%	680:685	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	0	33	theme	Starch	23:28	arg1	Composition					30:40	Endosperm Starch Composition	13:40	Endosperm Starch Composition	13:40	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.					
35324697	9	34	theme	type	1502:1505	arg1	kernels					1507:1513	the maize type kernels	1492:1513	the maize type kernels	1492:1513	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	4	35	theme	maize	352:356	arg1	populations					358:368	maize populations	352:368	maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics	352:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	4	36	from	responses	324:332	arg1	populations					358:368	maize populations	352:368	maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics	352:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	9	37	theme	infection	1391:1399	arg1	risk					1376:1379	the risk	1372:1379	the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol)	1372:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	0	38	theme	Endosperm	13:21	arg1	Composition					30:40	Endosperm Starch Composition	13:40	Endosperm Starch Composition	13:40	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.					
35324697	3	39	theme	maize	259:263	arg1	rot					269:271	maize ear rot	259:271	maize ear rot	259:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	6	40	theme	mg	795:796	arg1	kg-1					798:801	7.40 mg kg-1	790:801	7.40 mg kg-1	790:801	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	40	theme	mg	795:796	arg1	beauvericin					777:787	beauvericin	777:787	beauvericin (7.40 mg kg-1)	777:802	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	4	41	with	plants	454:459	arg1	characteristics					486:500	intermediate kernel characteristics	466:500	intermediate kernel characteristics	466:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	7	42	from	0.364	1105:1109	arg1	0.785					1122:1126	0.785	1122:1126	0.785	1122:1126	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	43	from	0.396	999:1003	arg1	0.735					1016:1020	0.735	1016:1020	0.735	1016:1020	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	3	44	theme	causative	239:247	arg1	factor					249:254	a frequent causative factor	228:254	a frequent causative factor of maize ear rot	228:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	8	45	dep	IFER	1172:1175	arg1	amylose					1182:1188	(IFER) and amylose content	1171:1196	amylose	1182:1188	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	0	46	theme	Composition	30:40	arg1	Influence					0:8	Influence	0:8	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.	0:89	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.					
35324697	8	47	theme	endosperm	1262:1270	arg1	composition					1279:1289	the endosperm starch composition	1258:1289	the endosperm starch composition	1258:1289	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	9	48	with	contamination	1405:1417	arg1	metabolites					1431:1441	fungal metabolites	1424:1441	fungal metabolites (beauvericin and ergosterol)	1424:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	48	with	contamination	1405:1417	arg1	ergosterol					1460:1469	ergosterol	1460:1469	ergosterol	1460:1469	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	48	with	contamination	1405:1417	arg1	beauvericin					1444:1454	beauvericin	1444:1454	beauvericin	1444:1454	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	6	49	theme	subpopulation	835:847	arg1	plants					809:814	plants	809:814	plants of the flint maize subpopulation	809:847	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	4	50	theme	plants	454:459	arg1	dent					433:436	dent	433:436	dent	433:436	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	4	50	theme	plants	454:459	arg1	flint					426:430	flint	426:430	flint	426:430	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	4	50	theme	plants	454:459	arg1	group					445:449	a group	443:449	a group of plants with intermediate kernel characteristics	443:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	4	50	theme	plants	454:459	arg1	plants					454:459	plants	454:459	plants with intermediate kernel characteristics	454:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	6	51	theme	IFER	743:746	arg1	infection					732:740	infection	732:740	infection (IFER = 2.10)	732:754	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	51	theme	IFER	743:746	arg1	2.10					750:753	IFER = 2.10	743:753	IFER = 2.10	743:753	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	8	52	theme	kernel	1298:1303	arg1	resistance					1305:1314	the kernel resistance	1294:1314	the kernel resistance to Fusarium ear rot	1294:1334	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	4	53	theme	study	297:301	arg1	aim					278:280	The aim	274:280	The aim of the present study	274:301	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	9	54	dep	metabolites	1431:1441	arg1	metabolites					1431:1441	fungal metabolites	1424:1441	fungal metabolites (beauvericin and ergosterol)	1424:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	54	dep	metabolites	1431:1441	arg1	ergosterol					1460:1469	ergosterol	1460:1469	ergosterol	1460:1469	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	54	dep	metabolites	1431:1441	arg1	beauvericin					1444:1454	beauvericin	1444:1454	beauvericin	1444:1454	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	0	55	theme	Maize	45:49	arg1	Response					51:58	Maize Response	45:58	Maize Response to Fusarium temperatum Scaufl	45:88	Influence of Endosperm Starch Composition on Maize Response to Fusarium temperatum Scaufl.					
35324697	4	56	theme	kernel	479:484	arg1	characteristics					486:500	intermediate kernel characteristics	466:500	intermediate kernel characteristics	466:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	7	57	theme	ergosterol	955:964	arg1	content					966:972	ergosterol content	955:972	ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018)	955:1029	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	8	58	theme	composition	1279:1289	arg1	role					1250:1253	the role	1246:1253	the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot	1246:1334	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	7	59	theme	rot	930:932	arg1	IFER					945:948	IFER	945:948	IFER	945:948	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	59	theme	rot	930:932	arg1	intensity					934:942	the Fusarium ear rot intensity	913:942	the Fusarium ear rot intensity (IFER)	913:949	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	60	theme	ear	926:928	arg1	IFER					945:948	IFER	945:948	IFER	945:948	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	60	theme	ear	926:928	arg1	intensity					934:942	the Fusarium ear rot intensity	913:942	the Fusarium ear rot intensity (IFER)	913:949	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	5	61	theme	tested	600:605	arg1	types					613:617	the tested maize types	596:617	the tested maize types	596:617	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	4	62	theme	intermediate	466:477	arg1	characteristics					486:500	intermediate kernel characteristics	466:500	intermediate kernel characteristics	466:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	3	63	theme	ear	265:267	arg1	rot					269:271	maize ear rot	259:271	maize ear rot	259:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	6	64	theme	infection	732:740	arg1	contamination					760:772	contamination	760:772	contamination by beauvericin (7.40 mg kg-1)	760:802	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	6	64	theme	infection	732:740	arg1	rates					723:727	significantly higher rates	702:727	significantly higher rates of infection (IFER = 2.10)	702:754	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	9	65	theme	fungal	1424:1429	arg1	metabolites					1431:1441	fungal metabolites	1424:1441	fungal metabolites (beauvericin and ergosterol)	1424:1470	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	65	theme	fungal	1424:1429	arg1	ergosterol					1460:1469	ergosterol	1460:1469	ergosterol	1460:1469	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	9	65	theme	fungal	1424:1429	arg1	beauvericin					1444:1454	beauvericin	1444:1454	beauvericin	1444:1454	The conducted study indicated that the risk of kernel infection and contamination with fungal metabolites (beauvericin and ergosterol) was associated with the maize type kernels.					
35324697	5	66	theme	inoculation	506:516	arg1	studies					518:524	inoculation studies	506:524	inoculation studies	506:524	In inoculation studies, substantial variation of host response to the fungus was found among the tested maize types.					
35324697	8	67	theme	negative	1142:1149	arg1	correlation					1151:1161	The negative correlation	1138:1161	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180)	1138:1235	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	3	68	theme	rot	269:271	arg1	factor					249:254	a frequent causative factor	228:254	a frequent causative factor of maize ear rot	228:271	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	3	68	theme	rot	269:271	arg1	fujikuroi					191:199	the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot	178:271	fujikuroi	191:199	& Munaut is a newly described taxon belonging to the Fusarium fujikuroi species complex (FFSC) and a frequent causative factor of maize ear rot.					
35324697	8	69	theme	starch	1272:1277	arg1	composition					1279:1289	the endosperm starch composition	1258:1289	the endosperm starch composition	1258:1289	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	7	70	dep	content	966:972	arg1	value					981:985	the R value	975:985	the R value ranged from 0.396 in 2015 to 0.735 in 2018	975:1028	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	4	71	theme	endosperm	383:391	arg1	features					393:400	endosperm features	383:400	endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics	383:500	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
35324697	7	72	theme	Fusarium	917:924	arg1	IFER					945:948	IFER	945:948	IFER	945:948	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	7	72	theme	Fusarium	917:924	arg1	intensity					934:942	the Fusarium ear rot intensity	913:942	the Fusarium ear rot intensity (IFER)	913:949	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	8	73	from	role	1250:1253	arg1	resistance					1305:1314	the kernel resistance	1294:1314	the kernel resistance to Fusarium ear rot	1294:1334	The negative correlation between (IFER) and amylose content (ranging from R = -0.303 to R= -0.180) stresses the role of the endosperm starch composition in the kernel resistance to Fusarium ear rot.					
35324697	6	74	theme	maize	829:833	arg1	subpopulation					835:847	the flint maize subpopulation	819:847	the flint maize subpopulation	819:847	The dent-type kernels contained significantly less amylose (28.27%) and exhibited significantly higher rates of infection (IFER = 2.10) and contamination by beauvericin (7.40 mg kg-1) than plants of the flint maize subpopulation.					
35324697	7	75	dep	0.735	1016:1020	arg1	to					1013:1014	to	1013:1014	to	1013:1014	The study documents a significant positive correlation between the Fusarium ear rot intensity (IFER) and ergosterol content (the R value ranged from 0.396 in 2015 to 0.735 in 2018) and between IFER and the presence of beauvericin (the R value ranged from 0.364 in 2015 to 0.785 in 2017).					
35324697	4	76	theme	present	289:295	arg1	study					297:301	the present study	285:301	the present study	285:301	The aim of the present study was to determine the responses to the disease in maize populations differing in endosperm features that were classified to flint, dent, and a group of plants with intermediate kernel characteristics.					
36348240	0	0	theme	toxic	98:102	arg1	species					104:110	some toxic species	93:110	some toxic species	93:110	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	13	1	theme	Ch-Er	1510:1514	arg1	3GO2R10					1516:1522	(Ch-Er)3GO2R10	1509:1522	(Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively	1509:1566	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	1	2	with	crosslinking	228:239	arg1	ratios					263:268	different weight ratios	246:268	different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	246:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	12	3	theme	cation	1402:1407	arg1	elimination					1351:1361	simultaneous elimination	1338:1361	simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions	1338:1439	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	1	4	theme	weight	256:261	arg1	ratios					263:268	different weight ratios	246:268	different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	246:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	12	5	theme	formulations	1288:1299	arg1	samples					1264:1270	The optimum samples	1252:1270	The optimum samples of the prepared formulations	1252:1299	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	12	5	theme	formulations	1288:1299	arg1	materials					1324:1332	sorbent materials	1316:1332	sorbent materials	1316:1332	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	9	6	theme	different	860:868	arg1	tools					881:885	different analytical tools	860:885	different analytical tools	860:885	The prepared samples were investigated by different analytical tools.					
36348240	13	7	theme	Hg2+	1481:1484	arg1	cation					1486:1491	Hg2+ cation	1481:1491	Hg2+ cation	1481:1491	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	5	8	theme	optimized	593:601	arg1	Ch-Er					615:619	(Ch-Er)3	614:621	(Ch-Er)3	614:621	The data revealed that the optimized sample was (Ch-Er)3.					
36348240	5	8	theme	optimized	593:601	arg1	sample					603:608	the optimized sample	589:608	the optimized sample	589:608	The data revealed that the optimized sample was (Ch-Er)3.					
36348240	9	9	theme	analytical	870:879	arg1	tools					881:885	different analytical tools	860:885	different analytical tools	860:885	The prepared samples were investigated by different analytical tools.					
36348240	0	10	theme	species	104:110	arg1	removal					82:88	simultaneous removal	69:88	simultaneous removal of some toxic species from simulated solution	69:134	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	1	11	from	Ch-Er	295:299	arg1	ratios					263:268	different weight ratios	246:268	different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	246:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	1	11	from	Ch-Er	295:299	arg1	Er					285:286	Er	285:286	Er	285:286	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	1	11	from	Ch-Er	295:299	arg1	erythritol					273:282	erythritol	273:282	erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	273:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	11	12	theme	higher	1181:1186	arg1	e-beam					1195:1200	higher energy e-beam	1181:1200	higher energy e-beam	1181:1200	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	12	13	theme	dye	1386:1388	arg1	elimination					1351:1361	simultaneous elimination	1338:1361	simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions	1338:1439	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	1	14	theme	erythritol	273:282	arg1	ratios					263:268	different weight ratios	246:268	different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	246:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	10	15	theme	sample	907:912	arg1	3GO2					921:924	the adjusted sample (Ch-Er)3GO2	894:924	the adjusted sample (Ch-Er)3GO2	894:924	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	3	16	theme	FTIR	409:412	arg1	spectroscopy					414:425	FTIR spectroscopy	409:425	FTIR spectroscopy	409:425	The chemical modification was proved via FTIR spectroscopy.					
36348240	3	17	theme	chemical	372:379	arg1	modification					381:392	The chemical modification	368:392	The chemical modification	368:392	The chemical modification was proved via FTIR spectroscopy.					
36348240	0	18	theme	simulated	117:125	arg1	solution					127:134	simulated solution	117:134	simulated solution	117:134	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	10	19	theme	adjusted	898:905	arg1	3GO2					921:924	the adjusted sample (Ch-Er)3GO2	894:924	the adjusted sample (Ch-Er)3GO2	894:924	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	12	20	theme	optimum	1256:1262	arg1	samples					1264:1270	The optimum samples	1252:1270	The optimum samples of the prepared formulations	1252:1299	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	12	20	theme	optimum	1256:1262	arg1	materials					1324:1332	sorbent materials	1316:1332	sorbent materials	1316:1332	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	13	21	theme	MB	1470:1471	arg1	dye					1473:1475	MB dye	1470:1475	MB dye	1470:1475	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	11	22	theme	surface	1150:1156	arg1	roughness					1158:1166	surface roughness	1150:1166	surface roughness	1150:1166	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	11	23	theme	AFM	1074:1076	arg1	data					1078:1081	The AFM data	1070:1081	The AFM data of the irradiated samples	1070:1107	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	12	24	theme	simultaneous	1338:1349	arg1	elimination					1351:1361	simultaneous elimination	1338:1361	simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions	1338:1439	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	8	25	theme	Ch-Er	749:753	arg1	3GO1					755:758	(Ch-Er)3GO1	748:758	(Ch-Er)3GO1	748:758	(symbolized as (Ch-Er)3GO1, (Ch-Er)3GO2, (Ch-Er)3GO4, and (Ch-Er)3GO8 respectively).					
36348240	0	26	theme	Green	0:4	arg1	synthesis					6:14	Green synthesis	0:14	Green synthesis of chitosan/erythritol/graphene oxide	0:52	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	4	27	theme	microscopy	490:499	arg1	investigation					507:519	an atomic force microscopy (AFM) investigation	474:519	an atomic force microscopy (AFM) investigation for their topography and surface properties	474:563	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	6	28	theme	oxide	696:700	arg1	wt					725:726	graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	687:726	graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	687:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	12	29	theme	blue	1376:1379	arg1	dye					1386:1388	methylene blue (MB) dye	1366:1388	methylene blue (MB) dye	1366:1388	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	0	30	theme	chitosan/erythritol/graphene	19:46	arg1	oxide					48:52	chitosan/erythritol/graphene oxide	19:52	chitosan/erythritol/graphene oxide	19:52	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	4	31	theme	force	484:488	arg1	microscopy					490:499	atomic force microscopy	477:499	an atomic force microscopy (AFM) investigation for their topography and surface properties	474:563	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	4	31	theme	force	484:488	arg1	AFM					502:504	AFM	502:504	AFM	502:504	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	13	32	dep	3GO2R10	1516:1522	arg1	186.23 mg g-1					1525:1537	186.23 mg g-1	1525:1537	186.23 mg g-1	1525:1537	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	13	32	dep	3GO2R10	1516:1522	arg1	205 mg g-1					1543:1552	205 mg g-1	1543:1552	205 mg g-1	1543:1552	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	6	33	theme	graphene	687:694	arg1	oxide					696:700	graphene oxide	687:700	graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	687:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	6	34	mod	modified	648:655	arg3	ratios					677:682	different weight ratios	660:682	different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	660:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	6	34	mod	modified	648:655	arg1	sample					629:634	This sample	624:634	This sample	624:634	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	1	35	theme	green	181:185	arg1	methodology					187:197	green methodology	181:197	green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	181:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	8	36	theme	Ch-Er	775:779	arg1	3GO4					781:784	(Ch-Er)3GO4	774:784	(Ch-Er)3GO4	774:784	(symbolized as (Ch-Er)3GO1, (Ch-Er)3GO2, (Ch-Er)3GO4, and (Ch-Er)3GO8 respectively).					
36348240	12	37	dep	blue	1376:1379	arg1	MB					1382:1383	MB	1382:1383	MB	1382:1383	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	8	38	theme	Ch-Er	762:766	arg1	3GO2					768:771	(Ch-Er)3GO2	761:771	(Ch-Er)3GO2	761:771	(symbolized as (Ch-Er)3GO1, (Ch-Er)3GO2, (Ch-Er)3GO4, and (Ch-Er)3GO8 respectively).					
36348240	2	39	theme	thin	356:359	arg1	films					361:365	thin films	356:365	thin films	356:365	The products were casted in the form of thin films.					
36348240	11	40	theme	irradiated	1090:1099	arg1	samples					1101:1107	the irradiated samples	1086:1107	the irradiated samples	1086:1107	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	10	41	theme	Ch-Er	915:919	arg1	3GO2					921:924	the adjusted sample (Ch-Er)3GO2	894:924	the adjusted sample (Ch-Er)3GO2	894:924	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	11	42	theme	more	1226:1229	arg1	points					1244:1249	more crosslinking points	1226:1249	more crosslinking points	1226:1249	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	11	43	theme	energy	1188:1193	arg1	e-beam					1195:1200	higher energy e-beam	1181:1200	higher energy e-beam	1181:1200	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	0	44	theme	oxide	48:52	arg1	synthesis					6:14	Green synthesis	0:14	Green synthesis of chitosan/erythritol/graphene oxide	0:52	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	13	45	theme	maximum	1446:1452	arg1	removal					1454:1460	The maximum removal	1442:1460	The maximum removal of both MB dye and Hg2+ cation	1442:1491	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	1	46	from	ratios	263:268	arg1	Ch-Er					295:299	Ch-Er	295:299	Ch-Er	295:299	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	12	47	from	solutions	1431:1439	arg1	elimination					1351:1361	simultaneous elimination	1338:1361	simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions	1338:1439	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	1	48	theme	sonication	209:218	arg1	crosslinking					228:239	sonication induced crosslinking	209:239	sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	209:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	0	49	theme	simultaneous	69:80	arg1	removal					82:88	simultaneous removal	69:88	simultaneous removal of some toxic species from simulated solution	69:134	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	10	50	theme	electron	944:951	arg1	e-beam					959:964	e-beam	959:964	e-beam	959:964	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	50	theme	electron	944:951	arg1	beam					953:956	electron beam	944:956	electron beam (e-beam) at 10	944:971	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	4	51	theme	atomic	477:482	arg1	microscopy					490:499	atomic force microscopy	477:499	an atomic force microscopy (AFM) investigation for their topography and surface properties	474:563	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	4	51	theme	atomic	477:482	arg1	AFM					502:504	AFM	502:504	AFM	502:504	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	10	52	from	10	970:971	arg1	20 kGy					977:982	20 kGy	977:982	20 kGy	977:982	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	52	from	10	970:971	arg1	e-beam					959:964	e-beam	959:964	e-beam	959:964	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	52	from	10	970:971	arg1	beam					953:956	electron beam	944:956	electron beam (e-beam) at 10	944:971	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	0	53	from	solution	127:134	arg1	removal					82:88	simultaneous removal	69:88	simultaneous removal of some toxic species from simulated solution	69:134	Green synthesis of chitosan/erythritol/graphene oxide composites for simultaneous removal of some toxic species from simulated solution.					
36348240	13	54	theme	dye	1473:1475	arg1	removal					1454:1460	The maximum removal	1442:1460	The maximum removal of both MB dye and Hg2+ cation	1442:1491	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	6	55	theme	weight	670:675	arg1	ratios					677:682	different weight ratios	660:682	different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	660:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	12	56	theme	simulated	1421:1429	arg1	solutions					1431:1439	simulated solutions	1421:1439	simulated solutions	1421:1439	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	12	57	theme	sorbent	1316:1322	arg1	samples					1264:1270	The optimum samples	1252:1270	The optimum samples of the prepared formulations	1252:1299	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	12	57	theme	sorbent	1316:1322	arg1	materials					1324:1332	sorbent materials	1316:1332	sorbent materials	1316:1332	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	6	58	theme	wt	725:726	arg1	ratios					677:682	different weight ratios	660:682	different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	660:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	6	59	theme	different	660:668	arg1	ratios					677:682	different weight ratios	660:682	different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt	660:726	This sample was further modified by different weight ratios of graphene oxide 0.1, 0.2, 0.4, and 0.8 wt.					
36348240	8	60	theme	Ch-Er	792:796	arg1	3GO8					798:801	(Ch-Er)3GO8	791:801	(Ch-Er)3GO8	791:801	(symbolized as (Ch-Er)3GO1, (Ch-Er)3GO2, (Ch-Er)3GO4, and (Ch-Er)3GO8 respectively).					
36348240	9	61	theme	prepared	822:829	arg1	samples					831:837	The prepared samples	818:837	The prepared samples	818:837	The prepared samples were investigated by different analytical tools.					
36348240	1	62	theme	induced	220:226	arg1	crosslinking					228:239	sonication induced crosslinking	209:239	sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	209:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
36348240	11	63	theme	samples	1101:1107	arg1	data					1078:1081	The AFM data	1070:1081	The AFM data of the irradiated samples	1070:1107	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	10	64	theme	doses	999:1003	arg1	20 kGy					977:982	20 kGy	977:982	20 kGy	977:982	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	64	theme	doses	999:1003	arg1	e-beam					959:964	e-beam	959:964	e-beam	959:964	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	64	theme	doses	999:1003	arg1	beam					953:956	electron beam	944:956	electron beam (e-beam) at 10	944:971	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	12	65	theme	mercury	1394:1400	arg1	Hg2+					1410:1413	Hg2+	1410:1413	Hg2+	1410:1413	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	12	65	theme	mercury	1394:1400	arg1	cation					1402:1407	mercury cation	1394:1407	mercury cation (Hg2+)	1394:1414	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	10	66	dep	give	1008:1011	arg1	Ch-Er					1041:1045	Ch-Er	1041:1045	Ch-Er	1041:1045	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	10	66	dep	give	1008:1011	arg1	Ch-Er					1022:1026	Ch-Er	1022:1026	Ch-Er	1022:1026	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	11	67	theme	crosslinking	1231:1242	arg1	points					1244:1249	more crosslinking points	1226:1249	more crosslinking points	1226:1249	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	2	68	theme	films	361:365	arg1	form					348:351	the form	344:351	the form of thin films	344:365	The products were casted in the form of thin films.					
36348240	10	69	theme	irradiation	987:997	arg1	doses					999:1003	irradiation doses	987:1003	irradiation doses	987:1003	Then, the adjusted sample (Ch-Er)3GO2 was irradiated by electron beam (e-beam) at 10 and 20 kGy of irradiation doses to give samples (Ch-Er)3GO2R10 and (Ch-Er)3GO2R20, respectively.					
36348240	11	70	theme	pore	1125:1128	arg1	size					1130:1133	the pore size	1121:1133	the pore size	1121:1133	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	4	71	theme	modified	438:445	arg1	products					447:454	the modified products	434:454	the modified products	434:454	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	4	72	theme	surface	546:552	arg1	properties					554:563	surface properties	546:563	surface properties	546:563	Then, the modified products were verified via an atomic force microscopy (AFM) investigation for their topography and surface properties.					
36348240	13	73	theme	cation	1486:1491	arg1	removal					1454:1460	The maximum removal	1442:1460	The maximum removal of both MB dye and Hg2+ cation	1442:1491	The maximum removal of both MB dye and Hg2+ cation was achieved by (Ch-Er)3GO2R10 (186.23 mg g-1 and 205 mg g-1) respectively.					
36348240	12	74	theme	prepared	1279:1286	arg1	formulations					1288:1299	the prepared formulations	1275:1299	the prepared formulations	1275:1299	The optimum samples of the prepared formulations were tested as sorbent materials for simultaneous elimination of methylene blue (MB) dye and mercury cation (Hg2+) from simulated solutions.					
36348240	11	75	theme	points	1244:1249	arg1	formation					1213:1221	the formation	1209:1221	the formation of more crosslinking points	1209:1249	The AFM data of the irradiated samples showed that the pore size decreases, and surface roughness increases at higher energy e-beam due to the formation of more crosslinking points.					
36348240	1	76	theme	different	246:254	arg1	ratios					263:268	different weight ratios	246:268	different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4	246:313	In this study, chitosan (Ch) is adapted via green methodology including sonication induced crosslinking with different weight ratios of erythritol (Er) from (Ch-Er)1 to (Ch-Er)4.					
35851663	8	0	theme	optimal	1010:1016	arg1	conditions					1018:1027	the optimal conditions	1006:1027	the optimal conditions	1006:1027	Under the optimal conditions, the linear ranges for H2O2 and glucose were 0.625-40 µM and 1.9-125 µM, respectively, and the detection limits were 0.12 µM and 0.69 µM, respectively.					
35851663	8	1	theme	detection	1124:1132	arg1	limits					1134:1139	the detection limits	1120:1139	the detection limits	1120:1139	Under the optimal conditions, the linear ranges for H2O2 and glucose were 0.625-40 µM and 1.9-125 µM, respectively, and the detection limits were 0.12 µM and 0.69 µM, respectively.					
35851663	8	1	theme	detection	1124:1132	arg1	0.12 µM					1146:1152	0.12 µM	1146:1152	0.12 µM	1146:1152	Under the optimal conditions, the linear ranges for H2O2 and glucose were 0.625-40 µM and 1.9-125 µM, respectively, and the detection limits were 0.12 µM and 0.69 µM, respectively.					
35851663	7	2	theme	color	876:880	arg1	changes					882:888	the TMB color changes	868:888	the TMB color changes	868:888	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	9	3	theme	human	1240:1244	arg1	samples					1252:1258	diluted human serum samples	1232:1258	diluted human serum samples spiked with glucose	1232:1278	The colorimetric assay was also applied to analyze diluted human serum samples spiked with glucose.					
35851663	7	4	theme	H2O2	947:950	arg1	detection					934:942	the detection	930:942	the detection of H2O2 and glucose at an absorption wavelength 652 nm	930:997	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	1	5	theme	colloidal	147:155	arg1	nanoparticles					157:169	colloidal nanoparticles	147:169	colloidal nanoparticles	147:169	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	10	6	theme	nanozyme	1344:1351	arg1	composite					1353:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	4	7	theme	quantum	582:588	arg1	yield					590:594	fluorescence quantum yield	569:594	fluorescence quantum yield	569:594	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	0	8	theme	colorimetric	79:90	arg1	detection					92:100	the colorimetric detection	75:100	the colorimetric detection of hydrogen peroxide and glucose	75:133	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	4	9	theme	containing	486:495	arg1	Cu					506:507	Cu	506:507	Cu	506:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	9	theme	containing	486:495	arg1	%					501:501	The Cu-CDs containing 6.88%	475:501	The Cu-CDs containing 6.88% of Cu	475:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	5	10	theme	amino	666:670	arg1	Cu-CDs					682:687	Cu-CDs	682:687	Cu-CDs	682:687	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	10	theme	amino	666:670	arg1	groups					672:677	the amino groups	662:677	the amino groups of Cu-CDs and those of chitosan	662:709	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	10	theme	amino	666:670	arg1	those					693:697	those	693:697	those	693:697	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	4	11	theme	fluorescence	569:580	arg1	yield					590:594	fluorescence quantum yield	569:594	fluorescence quantum yield	569:594	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	0	12	theme	hydrogen	105:112	arg1	peroxide					114:121	hydrogen peroxide	105:121	hydrogen peroxide	105:121	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	4	13	theme	Cu-CDs	479:484	arg1	Cu					506:507	Cu	506:507	Cu	506:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	13	theme	Cu-CDs	479:484	arg1	%					501:501	The Cu-CDs containing 6.88%	475:501	The Cu-CDs containing 6.88% of Cu	475:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	8	14	theme	linear	1034:1039	arg1	ranges					1041:1046	the linear ranges	1030:1046	the linear ranges for H2O2 and glucose	1030:1067	Under the optimal conditions, the linear ranges for H2O2 and glucose were 0.625-40 µM and 1.9-125 µM, respectively, and the detection limits were 0.12 µM and 0.69 µM, respectively.					
35851663	8	14	theme	linear	1034:1039	arg1	0.625-40 µM					1074:1084	0.625-40 µM	1074:1084	0.625-40 µM	1074:1084	Under the optimal conditions, the linear ranges for H2O2 and glucose were 0.625-40 µM and 1.9-125 µM, respectively, and the detection limits were 0.12 µM and 0.69 µM, respectively.					
35851663	5	15	theme	nanozyme/film	601:613	arg1	composite					615:623	The nanozyme/film composite	597:623	The nanozyme/film composite	597:623	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	1	16	theme	nanoparticles	157:169	arg1	use					140:142	The use	136:142	The use of colloidal nanoparticles	136:169	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	3	17	theme	rapid	442:446	arg1	method					467:472	a rapid microwave-assisted method	440:472	a rapid microwave-assisted method	440:472	Cu-CDs with high peroxidase activity were prepared by using a rapid microwave-assisted method.					
35851663	6	18	theme	oxidation	783:791	arg1	reaction					793:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	3	19	theme	high	392:395	arg1	activity					408:415	high peroxidase activity	392:415	high peroxidase activity	392:415	Cu-CDs with high peroxidase activity were prepared by using a rapid microwave-assisted method.					
35851663	7	20	theme	wavelength	981:990	arg1	652 nm					992:997	an absorption wavelength 652 nm	967:997	an absorption wavelength 652 nm	967:997	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	9	21	theme	colorimetric	1185:1196	arg1	assay					1198:1202	The colorimetric assay	1181:1202	The colorimetric assay	1181:1202	The colorimetric assay was also applied to analyze diluted human serum samples spiked with glucose.					
35851663	3	22	with	Cu-CDs	380:385	arg1	activity					408:415	high peroxidase activity	392:415	high peroxidase activity	392:415	Cu-CDs with high peroxidase activity were prepared by using a rapid microwave-assisted method.					
35851663	10	23	theme	significant	1406:1416	arg1	decrease					1418:1425	a significant decrease	1404:1425	a significant decrease in activity	1404:1437	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	0	24	theme	carbon	22:27	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of Cu-doped carbon	0:27	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	4	25	theme	2.25 nm	541:547	arg1	size					533:536	an average particle size	513:536	an average particle size of 2.25 nm	513:547	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	5	26	theme	those	693:697	arg1	Cu-CDs					682:687	Cu-CDs	682:687	Cu-CDs	682:687	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	26	theme	those	693:697	arg1	groups					672:677	the amino groups	662:677	the amino groups of Cu-CDs and those of chitosan	662:709	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	26	theme	those	693:697	arg1	those					693:697	those	693:697	those	693:697	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	6	27	theme	TMB	778:780	arg1	reaction					793:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	0	28	theme	Cu-doped	13:20	arg1	carbon					22:27	Cu-doped carbon	13:27	Cu-doped carbon	13:27	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	0	29	theme	peroxide	114:121	arg1	detection					92:100	the colorimetric detection	75:100	the colorimetric detection of hydrogen peroxide and glucose	75:133	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	7	30	from	652 nm	992:997	arg1	detection					934:942	the detection	930:942	the detection of H2O2 and glucose at an absorption wavelength 652 nm	930:997	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	0	31	theme	film	42:45	arg1	composite					47:55	film composite	42:55	film composite	42:55	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	0	31	theme	film	42:45	arg1	catalyst					62:69	a catalyst	60:69	a catalyst for the colorimetric detection of hydrogen peroxide and glucose	60:133	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	1	32	theme	potential	201:209	arg1	interference					217:228	potential color interference	201:228	potential color interference	201:228	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	10	33	theme	non-toxic	1314:1322	arg1	composite					1353:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	3	34	theme	microwave-assisted	448:465	arg1	method					467:472	a rapid microwave-assisted method	440:472	a rapid microwave-assisted method	440:472	Cu-CDs with high peroxidase activity were prepared by using a rapid microwave-assisted method.					
35851663	4	35	theme	particle	524:531	arg1	size					533:536	an average particle size	513:536	an average particle size of 2.25 nm	513:547	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	0	36	theme	glucose	127:133	arg1	detection					92:100	the colorimetric detection	75:100	the colorimetric detection of hydrogen peroxide and glucose	75:133	Synthesis of Cu-doped carbon dot/chitosan film composite as a catalyst for the colorimetric detection of hydrogen peroxide and glucose.					
35851663	5	37	theme	glutaraldehyde	717:730	arg1	linker					732:737	a glutaraldehyde linker	715:737	a glutaraldehyde linker	715:737	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	1	38	theme	color	211:215	arg1	interference					217:228	potential color interference	201:228	potential color interference	201:228	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	3	39	theme	peroxidase	397:406	arg1	activity					408:415	high peroxidase activity	392:415	high peroxidase activity	392:415	Cu-CDs with high peroxidase activity were prepared by using a rapid microwave-assisted method.					
35851663	4	40	theme	average	516:522	arg1	size					533:536	an average particle size	513:536	an average particle size of 2.25 nm	513:547	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	2	41	with	dots	351:354	arg1	chitosan					370:377	chitosan	370:377	chitosan	370:377	To overcome the limitations, a catalyst was developed by crosslinking Cu-doped carbon dots (Cu-CDs) with chitosan.					
35851663	6	42	theme	tetramethylbenzidine	756:775	arg1	reaction					793:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	10	43	from	decrease	1418:1425	arg1	activity					1430:1437	activity	1430:1437	activity	1430:1437	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	6	44	theme	H2O2-mediated	742:754	arg1	reaction					793:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction	740:800	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	6	45	theme	film	853:856	arg1	activity					837:844	the peroxidase activity	822:844	the peroxidase activity of the film	822:856	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	7	46	theme	colorimetric	891:902	arg1	assays					904:909	colorimetric assays	891:909	colorimetric assays	891:909	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	5	47	theme	Cu-CDs	682:687	arg1	Cu-CDs					682:687	Cu-CDs	682:687	Cu-CDs	682:687	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	47	theme	Cu-CDs	682:687	arg1	groups					672:677	the amino groups	662:677	the amino groups of Cu-CDs and those of chitosan	662:709	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	5	47	theme	Cu-CDs	682:687	arg1	those					693:697	those	693:697	those	693:697	The nanozyme/film composite was prepared by crosslinking between the amino groups of Cu-CDs and those of chitosan via a glutaraldehyde linker.					
35851663	9	48	theme	diluted	1232:1238	arg1	samples					1252:1258	diluted human serum samples	1232:1258	diluted human serum samples spiked with glucose	1232:1278	The colorimetric assay was also applied to analyze diluted human serum samples spiked with glucose.					
35851663	10	49	theme	biodegradable	1299:1311	arg1	composite					1353:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	2	50	theme	carbon	344:349	arg1	dots					351:354	Cu-doped carbon dots	335:354	Cu-doped carbon dots (Cu-CDs) with chitosan	335:377	To overcome the limitations, a catalyst was developed by crosslinking Cu-doped carbon dots (Cu-CDs) with chitosan.					
35851663	2	50	theme	carbon	344:349	arg1	Cu-CDs					357:362	Cu-CDs	357:362	Cu-CDs	357:362	To overcome the limitations, a catalyst was developed by crosslinking Cu-doped carbon dots (Cu-CDs) with chitosan.					
35851663	10	51	theme	easy-to-handle	1329:1342	arg1	composite					1353:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	this biodegradable, non-toxic, and easy-to-handle nanozyme composite	1294:1361	Furthermore, this biodegradable, non-toxic, and easy-to-handle nanozyme composite could be stored for over 4 weeks without a significant decrease in activity.					
35851663	1	52	theme	interference	217:228	arg1	drawbacks					188:196	the drawbacks	184:196	the drawbacks of potential color interference and substrate-induced aggregation	184:262	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	6	53	theme	peroxidase	826:835	arg1	activity					837:844	the peroxidase activity	822:844	the peroxidase activity of the film	822:856	A H2O2-mediated tetramethylbenzidine (TMB) oxidation reaction was use to evaluate the peroxidase activity of the film.					
35851663	2	54	theme	Cu-doped	335:342	arg1	dots					351:354	Cu-doped carbon dots	335:354	Cu-doped carbon dots (Cu-CDs) with chitosan	335:377	To overcome the limitations, a catalyst was developed by crosslinking Cu-doped carbon dots (Cu-CDs) with chitosan.					
35851663	2	54	theme	Cu-doped	335:342	arg1	Cu-CDs					357:362	Cu-CDs	357:362	Cu-CDs	357:362	To overcome the limitations, a catalyst was developed by crosslinking Cu-doped carbon dots (Cu-CDs) with chitosan.					
35851663	4	55	theme	yield	590:594	arg1	%					564:564	9%	563:564	9% of fluorescence quantum yield	563:594	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	55	theme	yield	590:594	arg1	yield					590:594	fluorescence quantum yield	569:594	fluorescence quantum yield	569:594	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	9	56	theme	serum	1246:1250	arg1	samples					1252:1258	diluted human serum samples	1232:1258	diluted human serum samples spiked with glucose	1232:1278	The colorimetric assay was also applied to analyze diluted human serum samples spiked with glucose.					
35851663	7	57	theme	absorption	970:979	arg1	652 nm					992:997	an absorption wavelength 652 nm	967:997	an absorption wavelength 652 nm	967:997	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	4	58	contain	had	509:511	arg1	Cu					506:507	Cu	506:507	Cu	506:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	58	contain	had	509:511	arg1	%					501:501	The Cu-CDs containing 6.88%	475:501	The Cu-CDs containing 6.88% of Cu	475:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	58	contain	had	509:511	arg2	size					533:536	an average particle size	513:536	an average particle size of 2.25 nm	513:547	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	1	59	theme	substrate-induced	234:250	arg1	aggregation					252:262	substrate-induced aggregation	234:262	substrate-induced aggregation	234:262	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
35851663	4	60	theme	Cu	506:507	arg1	Cu					506:507	Cu	506:507	Cu	506:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	4	60	theme	Cu	506:507	arg1	%					501:501	The Cu-CDs containing 6.88%	475:501	The Cu-CDs containing 6.88% of Cu	475:507	The Cu-CDs containing 6.88% of Cu had an average particle size of 2.25 nm and exhibited 9% of fluorescence quantum yield.					
35851663	7	61	theme	glucose	956:962	arg1	detection					934:942	the detection	930:942	the detection of H2O2 and glucose at an absorption wavelength 652 nm	930:997	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	7	62	theme	TMB	872:874	arg1	changes					882:888	the TMB color changes	868:888	the TMB color changes	868:888	Based on the TMB color changes, colorimetric assays were developed for the detection of H2O2 and glucose at an absorption wavelength 652 nm.					
35851663	1	63	theme	aggregation	252:262	arg1	drawbacks					188:196	the drawbacks	184:196	the drawbacks of potential color interference and substrate-induced aggregation	184:262	The use of colloidal nanoparticles suffers from the drawbacks of potential color interference and substrate-induced aggregation.					
36797363	8	0	from	usage	1423:1427	arg1	systems					1482:1488	drug delivery systems	1468:1488	drug delivery systems	1468:1488	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	7	1	dep	[Formula	1313:1320	arg1	see					1323:1325	see	1323:1325	see text	1323:1330	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	6	2	from	pH	1112:1113	arg1	model					1098:1102	the preferred kinetic model	1076:1102	the preferred kinetic model at each pH	1076:1113	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	1	3	theme	test	351:354	arg1	system					356:361	the test system	347:361	the test system	347:361	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	4	4	theme	different	810:818	arg1	pHs					820:822	four different pHs	805:822	four different pHs	805:822	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	6	5	theme	preferred	1080:1088	arg1	model					1098:1102	the preferred kinetic model	1076:1102	the preferred kinetic model at each pH	1076:1113	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	5	6	from	pH	864:865	arg1	%					913:913	42.8, 63, 80, and 84.5%	891:913	42.8, 63, 80, and 84.5%	891:913	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	5	6	from	pH	864:865	arg1	release					853:859	The maximum cumulative drug release	825:859	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9	825:884	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	1	7	theme	trihydric	270:278	arg1	alcohol					280:286	trihydric alcohol	270:286	trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system	270:361	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	2	8	used	used	420:423	arg2	XRD					370:372	XRD	370:372	XRD	370:372	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	2	8	used	used	420:423	arg2	FTIR					364:367	FTIR	364:367	FTIR	364:367	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	2	8	used	used	420:423	arg2	TGA					384:386	TGA	384:386	TGA	384:386	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	2	8	used	used	420:423	arg2	SEM					375:377	SEM	375:377	SEM	375:377	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	4	9	theme	formed	661:666	arg1	hydrogel					668:675	the formed hydrogel	657:675	the formed hydrogel	657:675	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	5	10	theme	cumulative	837:846	arg1	%					913:913	42.8, 63, 80, and 84.5%	891:913	42.8, 63, 80, and 84.5%	891:913	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	5	10	theme	cumulative	837:846	arg1	release					853:859	The maximum cumulative drug release	825:859	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9	825:884	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	2	11	theme	hydrogel	511:518	arg1	properties					476:485	the physical/chemical properties	454:485	the physical/chemical properties of the formed composite hydrogel	454:518	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	6	12	theme	algorithmic	1148:1158	arg1	technique					1160:1168	TOPSIS algorithmic technique	1141:1168	TOPSIS algorithmic technique	1141:1168	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	3	13	theme	exponential	533:543	arg1	equation					545:552	an exponential equation	530:552	an exponential equation	530:552	By using an exponential equation, swelling behavior of the hydrogel was evaluated.					
36797363	5	14	theme	drug	848:851	arg1	%					913:913	42.8, 63, 80, and 84.5%	891:913	42.8, 63, 80, and 84.5%	891:913	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	5	14	theme	drug	848:851	arg1	release					853:859	The maximum cumulative drug release	825:859	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9	825:884	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	6	15	theme	TOPSIS	1141:1146	arg1	technique					1160:1168	TOPSIS algorithmic technique	1141:1168	TOPSIS algorithmic technique	1141:1168	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	2	16	theme	composite	501:509	arg1	hydrogel					511:518	the formed composite hydrogel	490:518	the formed composite hydrogel	490:518	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	8	17	theme	study	1386:1390	arg1	results					1363:1369	The results	1359:1369	The results of the present study	1359:1390	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	1	18	theme	bacterial	199:207	arg1	cellulose					209:217	bacterial cellulose	199:217	bacterial cellulose	199:217	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	8	19	theme	present	1378:1384	arg1	study					1386:1390	the present study	1374:1390	the present study	1374:1390	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	6	20	theme	first-order	1049:1059	arg1	equations					1061:1069	first-order equations	1049:1069	first-order equations	1049:1069	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	0	21	theme	algorithm	22:30	arg1	Application					0:10	Application	0:10	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.	0:150	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	0	22	theme	model	140:144	arg1	drug					146:149	a model drug	138:149	a model drug	138:149	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	7	23	from	capacity	1186:1193	arg1	relation					1214:1221	relation	1214:1221	relation to MB	1214:1227	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	3	24	theme	swelling	555:562	arg1	behavior					564:571	swelling behavior	555:571	swelling behavior of the hydrogel	555:587	By using an exponential equation, swelling behavior of the hydrogel was evaluated.					
36797363	7	25	theme	hydrogel	1202:1209	arg1	capacity					1186:1193	The adsorption capacity	1171:1193	The adsorption capacity of the hydrogel in relation to MB	1171:1227	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	0	26	theme	TOPSIS	15:20	arg1	algorithm					22:30	TOPSIS algorithm	15:30	TOPSIS algorithm	15:30	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	1	27	dep	the	247:249	arg1	aid					251:253	aid	251:253	aid	251:253	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	6	28	dep	models	986:991	arg1	models					986:991	five kinetic models	973:991	five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations)	973:1070	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	6	28	dep	models	986:991	arg1	equations					1061:1069	first-order equations	1049:1069	first-order equations	1049:1069	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	6	28	dep	models	986:991	arg1	Higuchi					1012:1018	Higuchi	1012:1018	Higuchi	1012:1018	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	6	28	dep	models	986:991	arg1	zero-order					1033:1042	zero-order	1033:1042	zero-order	1033:1042	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	2	29	theme	instrumental	391:402	arg1	techniques					404:413	instrumental techniques	391:413	instrumental techniques	391:413	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	8	30	theme	potential	1413:1421	arg1	usage					1423:1427	the potential usage	1409:1427	the potential usage of the developed composite hydrogel in drug delivery systems	1409:1488	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	7	31	theme	relationship	1283:1294	arg1	properties					1264:1273	thermodynamic properties	1250:1273	thermodynamic properties of this relationship	1250:1294	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	8	32	theme	composite	1446:1454	arg1	hydrogel					1456:1463	the developed composite hydrogel	1432:1463	the developed composite hydrogel	1432:1463	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	2	33	theme	physical/chemical	458:474	arg1	properties					476:485	the physical/chemical properties	454:485	the physical/chemical properties of the formed composite hydrogel	454:518	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	7	34	dep	[Formula	1337:1344	arg1	see					1347:1349	see	1347:1349	see text	1347:1354	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	1	35	with	alginate	220:227	arg1	the					247:249	the	247:249	the	247:249	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	8	36	theme	delivery	1473:1480	arg1	systems					1482:1488	drug delivery systems	1468:1488	drug delivery systems	1468:1488	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	4	37	theme	methylene	635:643	arg1	drug					629:632	a model drug	621:632	a model drug (methylene blue-MB)	621:652	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	4	37	theme	methylene	635:643	arg1	blue-MB					645:651	methylene blue-MB	635:651	methylene blue-MB	635:651	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	0	38	theme	cellulose-based	56:70	arg1	performance					91:101	bacterial cellulose-based composite hydrogel performance	46:101	bacterial cellulose-based composite hydrogel performance	46:101	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	0	39	theme	composite	72:80	arg1	performance					91:101	bacterial cellulose-based composite hydrogel performance	46:101	bacterial cellulose-based composite hydrogel performance	46:101	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	3	40	theme	hydrogel	580:587	arg1	behavior					564:571	swelling behavior	555:571	swelling behavior of the hydrogel	555:587	By using an exponential equation, swelling behavior of the hydrogel was evaluated.					
36797363	7	41	theme	adsorption	1175:1184	arg1	capacity					1186:1193	The adsorption capacity	1171:1193	The adsorption capacity of the hydrogel in relation to MB	1171:1227	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	0	42	theme	bacterial	46:54	arg1	performance					91:101	bacterial cellulose-based composite hydrogel performance	46:101	bacterial cellulose-based composite hydrogel performance	46:101	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	1	43	theme	hydrogen	329:336	arg1	bonds					338:342	hydrogen bonds	329:342	hydrogen bonds	329:342	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	1	44	with	cellulose	209:217	arg1	the					247:249	the	247:249	the	247:249	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	8	45	theme	developed	1436:1444	arg1	hydrogel					1456:1463	the developed composite hydrogel	1432:1463	the developed composite hydrogel	1432:1463	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	1	46	theme	bonds	338:342	arg1	re-distribution					310:324	re-distribution	310:324	re-distribution of hydrogen bonds	310:342	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	7	47	theme	thermodynamic	1250:1262	arg1	properties					1264:1273	thermodynamic properties	1250:1273	thermodynamic properties of this relationship	1250:1294	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	4	48	theme	release	713:719	arg1	characteristics					721:735	release characteristics	713:735	release characteristics of the MB where the medium solution for the release was prepared at four different pHs	713:822	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	4	49	theme	MB	744:745	arg1	characteristics					721:735	release characteristics	713:735	release characteristics of the MB where the medium solution for the release was prepared at four different pHs	713:822	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	4	50	theme	medium	757:762	arg1	solution					764:771	the medium solution	753:771	the medium solution for the release	753:787	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	8	51	theme	hydrogel	1456:1463	arg1	usage					1423:1427	the potential usage	1409:1427	the potential usage of the developed composite hydrogel in drug delivery systems	1409:1488	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36797363	0	52	theme	hydrogel	82:89	arg1	performance					91:101	bacterial cellulose-based composite hydrogel performance	46:101	bacterial cellulose-based composite hydrogel performance	46:101	Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug.					
36797363	5	53	theme	maximum	829:835	arg1	%					913:913	42.8, 63, 80, and 84.5%	891:913	42.8, 63, 80, and 84.5%	891:913	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	5	53	theme	maximum	829:835	arg1	release					853:859	The maximum cumulative drug release	825:859	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9	825:884	The maximum cumulative drug release at pH 2.8, 6, 7.4, and 9 were 42.8, 63, 80, and 84.5%, respectively.					
36797363	7	54	dep	quantified	1301:1310	arg1	[Formula					1313:1320	[Formula	1313:1320	[Formula: see text]	1313:1331	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	7	54	dep	quantified	1301:1310	arg1	[Formula					1337:1344	[Formula	1337:1344	[Formula: see text]	1337:1355	The adsorption capacity of the hydrogel in relation to MB was determined while thermodynamic properties of this relationship were quantified ([Formula: see text] and [Formula: see text]).					
36797363	6	55	theme	kinetic	978:984	arg1	zero-order					1033:1042	zero-order	1033:1042	zero-order	1033:1042	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	6	55	theme	kinetic	978:984	arg1	Higuchi					1012:1018	Higuchi	1012:1018	Higuchi	1012:1018	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	6	55	theme	kinetic	978:984	arg1	models					986:991	five kinetic models	973:991	five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations)	973:1070	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	4	56	theme	model	623:627	arg1	drug					629:632	a model drug	621:632	a model drug (methylene blue-MB)	621:652	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	4	56	theme	model	623:627	arg1	blue-MB					645:651	methylene blue-MB	635:651	methylene blue-MB	635:651	By incorporating a model drug (methylene blue-MB) in the formed hydrogel, experiments were directed to study release characteristics of the MB where the medium solution for the release was prepared at four different pHs.					
36797363	2	57	theme	formed	494:499	arg1	hydrogel					511:518	the formed composite hydrogel	490:518	the formed composite hydrogel	490:518	FTIR, XRD, SEM, and TGA as instrumental techniques were used to structurally characterize the physical/chemical properties of the formed composite hydrogel.					
36797363	6	58	theme	kinetic	1090:1096	arg1	model					1098:1102	the preferred kinetic model	1076:1102	the preferred kinetic model at each pH	1076:1113	Data fitting process was carried out using five kinetic models (Korsmeyer-Peppas, Higuchi, Hopfenberg, zero-order, and first-order equations) and the preferred kinetic model at each pH was estimated by applying TOPSIS algorithmic technique.					
36797363	1	59	with	gelatin	234:240	arg1	the					247:249	the	247:249	the	247:249	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	1	60	theme	multi-component	154:168	arg1	hydrogel					170:177	A multi-component hydrogel	152:177	A multi-component hydrogel	152:177	A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system.					
36797363	8	61	theme	drug	1468:1471	arg1	systems					1482:1488	drug delivery systems	1468:1488	drug delivery systems	1468:1488	The results of the present study were in favor of the potential usage of the developed composite hydrogel in drug delivery systems.					
36433832	6	0	theme	PGLA	1268:1271	arg1	suture					1273:1278	PGLA suture	1268:1278	PGLA suture	1268:1278	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	2	1	theme	composite	377:385	arg1	filament					387:394	nontoxic CGG/ACNF composite filament	359:394	nontoxic CGG/ACNF composite filament	359:394	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	8	2	theme	excellent	1529:1537	arg1	properties					1551:1560	excellent application properties	1529:1560	excellent application properties	1529:1560	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	7	3	theme	better	1378:1383	arg1	healing					1385:1391	better healing properties and less inflammation	1378:1424	healing	1385:1391	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	6	4	with	suture	1152:1157	arg1	cytocompatibility					1179:1195	cytocompatibility	1179:1195	cytocompatibility	1179:1195	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	6	4	with	suture	1152:1157	arg1	antibiosis					1164:1173	antibiosis	1164:1173	antibiosis	1164:1173	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	7	5	theme	silk	1439:1442	arg1	sutures					1453:1459	silk and PGLA sutures	1439:1459	silk and PGLA sutures	1439:1459	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	2	6	theme	CGG/ACNF	368:375	arg1	filament					387:394	nontoxic CGG/ACNF composite filament	359:394	nontoxic CGG/ACNF composite filament	359:394	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	3	7	with	comparison	642:651	arg1	sutures					706:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	4	8	theme	core-shell	807:816	arg1	structure					818:826	typical core-shell structure	799:826	typical core-shell structure	799:826	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	4	9	theme	good	903:906	arg1	properties					919:928	good mechanical properties	903:928	good mechanical properties	903:928	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	3	10	theme	CGG/ACNF	572:579	arg1	filament					581:588	the resultant CGG/ACNF filament	558:588	the resultant CGG/ACNF filament as a surgical suture	558:609	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	11	theme	surgical	595:602	arg1	suture					604:609	a surgical suture	593:609	a surgical suture	593:609	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	5	12	theme	suture	986:991	arg1	strength					943:950	tensile strength	935:950	tensile strength	935:950	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	5	12	theme	suture	986:991	arg1	strength					965:972	knotting strength	956:972	knotting strength	956:972	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	3	13	dep	sutures	706:712	arg1	glycolide					677:685	90% glycolide and 10% l-lactide	673:703	glycolide	677:685	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	13	dep	sutures	706:712	arg1	l-lactide					695:703	l-lactide	695:703	l-lactide	695:703	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	0	14	theme	Guar	92:95	arg1	Gum					97:99	Guar Gum	92:99	Guar Gum	92:99	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	1	15	contain	have	186:189	arg2	degradability					224:236	degradability	224:236	degradability	224:236	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	1	15	contain	have	186:189	arg1	sutures					178:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	1	15	contain	have	186:189	arg2	cytocompatibility					202:218	attractive cytocompatibility	191:218	attractive cytocompatibility	191:218	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	6	16	theme	growth	1213:1218	arg1	promotion					1220:1228	better growth promotion	1206:1228	better growth promotion of cells than silk suture	1206:1254	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	2	17	theme	guar	320:323	arg1	CGG					330:332	CGG	330:332	CGG	330:332	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	17	theme	guar	320:323	arg1	gum					325:327	cationic guar gum	311:327	cationic guar gum (CGG)	311:333	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	5	18	theme	knotting	956:963	arg1	strength					965:972	knotting strength	956:972	knotting strength	956:972	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	0	19	theme	Interfacial	105:115	arg1	Spinning					146:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	5	20	theme	PGLA	1119:1122	arg1	sutures					1124:1130	PGLA sutures	1119:1130	PGLA sutures	1119:1130	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	4	21	theme	orientation	874:884	arg1	index					886:890	a high orientation index	867:890	a high orientation index (0.74)	867:897	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	4	21	theme	orientation	874:884	arg1	0.74					893:896	0.74	893:896	0.74	893:896	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	2	22	theme	polyelectrolyte	447:461	arg1	IPC					477:479	IPC	477:479	IPC	477:479	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	22	theme	polyelectrolyte	447:461	arg1	complexation					463:474	interfacial polyelectrolyte complexation	435:474	interfacial polyelectrolyte complexation (IPC) spinning	435:489	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	23	theme	cationic	311:318	arg1	CGG					330:332	CGG	330:332	CGG	330:332	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	23	theme	cationic	311:318	arg1	gum					325:327	cationic guar gum	311:327	cationic guar gum (CGG)	311:333	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	7	24	theme	mice	1331:1334	arg1	experiment					1317:1326	the stitching experiment	1303:1326	the stitching experiment of mice with the CGG/ACNF suture	1303:1359	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	1	25	theme	attractive	191:200	arg1	cytocompatibility					202:218	attractive cytocompatibility	191:218	attractive cytocompatibility	191:218	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	4	26	theme	high	869:872	arg1	index					886:890	a high orientation index	867:890	a high orientation index (0.74)	867:897	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	4	26	theme	high	869:872	arg1	0.74					893:896	0.74	893:896	0.74	893:896	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	8	27	from	operations	1587:1596	arg1	suture					1485:1490	the CGG/ACNF suture	1472:1490	the CGG/ACNF suture with a simple preparation method and excellent application properties	1472:1560	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	8	27	from	operations	1587:1596	arg1	promising					1565:1573	promising	1565:1573	promising	1565:1573	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	5	28	theme	CGG/ACNF	1014:1021	arg1	filaments					1023:1031	twisting CGG/ACNF filaments	1005:1031	twisting CGG/ACNF filaments	1005:1031	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	2	29	theme	core-shell	410:419	arg1	structure					421:429	a unique core-shell structure	401:429	a unique core-shell structure	401:429	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	8	30	theme	application	1539:1549	arg1	properties					1551:1560	excellent application properties	1529:1560	excellent application properties	1529:1560	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	5	31	dep	strength	943:950	arg1	The					931:933	The	931:933	The	931:933	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	2	32	theme	unique	403:408	arg1	structure					421:429	a unique core-shell structure	401:429	a unique core-shell structure	401:429	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	0	33	theme	Core-Shell	0:9	arg1	Filament					11:18	Core-Shell Filament	0:18	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.	0:154	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	6	34	theme	cells	1233:1237	arg1	promotion					1220:1228	better growth promotion	1206:1228	better growth promotion of cells than silk suture	1206:1254	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	5	35	theme	similar	1078:1084	arg1	coefficient					1095:1105	a similar friction coefficient	1076:1105	a similar friction coefficient to silk and PGLA sutures	1076:1130	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	0	36	theme	Excellent	25:33	arg1	Healing					41:47	Excellent Wound Healing	25:47	Excellent Wound Healing Property	25:56	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	4	37	theme	nervation	832:840	arg1	pattern					842:848	nervation pattern	832:848	nervation pattern	832:848	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	0	38	theme	Complexation	133:144	arg1	Spinning					146:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	4	39	theme	CGG/ACNF	772:779	arg1	filament					781:788	the CGG/ACNF filament	768:788	the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface	768:856	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	3	40	theme	silk	658:661	arg1	sutures					706:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	41	theme	comprehensive	496:508	arg1	characterization					510:525	comprehensive characterization	496:525	comprehensive characterization	496:525	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	8	42	with	suture	1485:1490	arg1	method					1518:1523	a simple preparation method	1497:1523	a simple preparation method	1497:1523	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	8	42	with	suture	1485:1490	arg1	properties					1551:1560	excellent application properties	1529:1560	excellent application properties	1529:1560	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	8	43	theme	surgical	1578:1585	arg1	operations					1587:1596	surgical operations	1578:1596	surgical operations	1578:1596	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	0	44	theme	Polyelectrolyte	117:131	arg1	Spinning					146:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Interfacial Polyelectrolyte Complexation Spinning	105:153	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	5	45	theme	friction	1086:1093	arg1	coefficient					1095:1105	a similar friction coefficient	1076:1105	a similar friction coefficient to silk and PGLA sutures	1076:1130	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	3	46	theme	resultant	562:570	arg1	filament					581:588	the resultant CGG/ACNF filament	558:588	the resultant CGG/ACNF filament as a surgical suture	558:609	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	7	47	dep	healing	1385:1391	arg1	properties					1393:1402	properties	1393:1402	properties	1393:1402	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	1	48	theme	surgical	241:248	arg1	operations					250:259	surgical operations	241:259	surgical operations	241:259	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	0	49	theme	Healing	41:47	arg1	Property					49:56	Excellent Wound Healing Property	25:56	Excellent Wound Healing Property	25:56	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	4	50	with	filament	781:788	arg1	surface					850:856	the typical core-shell structure and nervation pattern surface	795:856	the typical core-shell structure and nervation pattern surface	795:856	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	7	51	with	experiment	1317:1326	arg1	suture					1354:1359	the CGG/ACNF suture	1341:1359	the CGG/ACNF suture	1341:1359	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	2	52	theme	cellulose	278:286	arg1	ACNF					301:304	ACNF	301:304	ACNF	301:304	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	52	theme	cellulose	278:286	arg1	nanofibrils					288:298	anionic cellulose nanofibrils	270:298	anionic cellulose nanofibrils (ACNF)	270:305	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	53	theme	interfacial	435:445	arg1	IPC					477:479	IPC	477:479	IPC	477:479	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	53	theme	interfacial	435:445	arg1	complexation					463:474	interfacial polyelectrolyte complexation	435:474	interfacial polyelectrolyte complexation (IPC) spinning	435:489	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	0	54	theme	Wound	35:39	arg1	Healing					41:47	Excellent Wound Healing	25:47	Excellent Wound Healing Property	25:56	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	2	55	theme	anionic	270:276	arg1	ACNF					301:304	ACNF	301:304	ACNF	301:304	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	55	theme	anionic	270:276	arg1	nanofibrils					288:298	anionic cellulose nanofibrils	270:298	anionic cellulose nanofibrils (ACNF)	270:305	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	7	56	theme	stitching	1307:1315	arg1	experiment					1317:1326	the stitching experiment	1303:1326	the stitching experiment of mice with the CGG/ACNF suture	1303:1359	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	5	57	contain	has	1072:1074	arg1	suture					1065:1070	CGG/ACNF suture	1056:1070	CGG/ACNF suture	1056:1070	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	5	57	contain	has	1072:1074	arg2	coefficient					1095:1105	a similar friction coefficient	1076:1105	a similar friction coefficient to silk and PGLA sutures	1076:1130	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	2	58	dep	complexation	463:474	arg1	spinning					482:489	spinning	482:489	interfacial polyelectrolyte complexation (IPC) spinning	435:489	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	2	59	theme	nontoxic	359:366	arg1	filament					387:394	nontoxic CGG/ACNF composite filament	359:394	nontoxic CGG/ACNF composite filament	359:394	Herein, anionic cellulose nanofibrils (ACNF) and cationic guar gum (CGG) are employed to produce nontoxic CGG/ACNF composite filament with a unique core-shell structure via interfacial polyelectrolyte complexation (IPC) spinning.					
36433832	8	60	theme	preparation	1506:1516	arg1	method					1518:1523	a simple preparation method	1497:1523	a simple preparation method	1497:1523	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	4	61	theme	mechanical	908:917	arg1	properties					919:928	good mechanical properties	903:928	good mechanical properties	903:928	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	8	62	theme	CGG/ACNF	1476:1483	arg1	suture					1485:1490	the CGG/ACNF suture	1472:1490	the CGG/ACNF suture with a simple preparation method and excellent application properties	1472:1560	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	8	62	theme	CGG/ACNF	1476:1483	arg1	promising					1565:1573	promising	1565:1573	promising	1565:1573	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	5	63	theme	CGG/ACNF	1056:1063	arg1	suture					1065:1070	CGG/ACNF suture	1056:1070	CGG/ACNF suture	1056:1070	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	0	64	with	Filament	11:18	arg1	Property					49:56	Excellent Wound Healing Property	25:56	Excellent Wound Healing Property	25:56	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	6	65	theme	CGG/ACNF	1143:1150	arg1	suture					1152:1157	CGG/ACNF suture	1143:1157	CGG/ACNF suture with antibiosis and cytocompatibility	1143:1195	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	7	66	theme	PGLA	1448:1451	arg1	sutures					1453:1459	silk and PGLA sutures	1439:1459	silk and PGLA sutures	1439:1459	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	6	67	theme	silk	1244:1247	arg1	suture					1249:1254	silk suture	1244:1254	silk suture	1244:1254	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	4	68	theme	structure	818:826	arg1	surface					850:856	the typical core-shell structure and nervation pattern surface	795:856	the typical core-shell structure and nervation pattern surface	795:856	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	4	69	theme	pattern	842:848	arg1	surface					850:856	the typical core-shell structure and nervation pattern surface	795:856	the typical core-shell structure and nervation pattern surface	795:856	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	5	70	theme	CGG/ACNF	977:984	arg1	suture					986:991	CGG/ACNF suture	977:991	CGG/ACNF suture prepared by twisting CGG/ACNF filaments	977:1031	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	4	71	theme	typical	799:805	arg1	structure					818:826	typical core-shell structure	799:826	typical core-shell structure	799:826	Results show that the CGG/ACNF filament with the typical core-shell structure and nervation pattern surface exhibits a high orientation index (0.74) and good mechanical properties.					
36433832	5	72	theme	tensile	935:941	arg1	strength					943:950	tensile strength	935:950	tensile strength	935:950	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	3	73	theme	%	675:675	arg1	glycolide					677:685	90% glycolide and 10% l-lactide	673:703	glycolide	677:685	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	74	theme	filament	581:588	arg1	application					531:541	application	531:541	application	531:541	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	74	theme	filament	581:588	arg1	characterization					510:525	comprehensive characterization	496:525	comprehensive characterization	496:525	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	7	75	theme	CGG/ACNF	1345:1352	arg1	suture					1354:1359	the CGG/ACNF suture	1341:1359	the CGG/ACNF suture	1341:1359	In addition, the stitching experiment of mice with the CGG/ACNF suture further confirms better healing properties and less inflammation in vivo than silk and PGLA sutures do.					
36433832	0	76	theme	Cellulose	66:74	arg1	Nanofibrils					76:86	Cellulose Nanofibrils	66:86	Cellulose Nanofibrils	66:86	Core-Shell Filament with Excellent Wound Healing Property Made of Cellulose Nanofibrils and Guar Gum via Interfacial Polyelectrolyte Complexation Spinning.					
36433832	5	77	theme	twisting	1005:1012	arg1	filaments					1023:1031	twisting CGG/ACNF filaments	1005:1031	twisting CGG/ACNF filaments	1005:1031	The tensile strength and knotting strength of CGG/ACNF suture prepared by twisting CGG/ACNF filaments increase by 69.5%, and CGG/ACNF suture has a similar friction coefficient to silk and PGLA sutures.					
36433832	3	78	theme	PGLA	667:670	arg1	sutures					706:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	silk and PGLA (90% glycolide and 10% l-lactide) sutures	658:712	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	1	79	theme	Natural	156:162	arg1	sutures					178:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	6	80	theme	better	1206:1211	arg1	promotion					1220:1228	better growth promotion	1206:1228	better growth promotion of cells than silk suture	1206:1254	Moreover, CGG/ACNF suture with antibiosis and cytocompatibility exhibits better growth promotion of cells than silk suture, similar to PGLA suture in vitro.					
36433832	8	81	theme	simple	1499:1504	arg1	method					1518:1523	a simple preparation method	1497:1523	a simple preparation method	1497:1523	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
36433832	3	82	dep	characterization	510:525	arg1	performance					543:553	performance	543:553	performance	543:553	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	3	82	dep	characterization	510:525	arg1	The					492:494	The	492:494	The	492:494	The comprehensive characterization and application performance of the resultant CGG/ACNF filament as a surgical suture are thoroughly investigated in comparison with silk and PGLA (90% glycolide and 10% l-lactide) sutures in vitro and in vivo, respectively.					
36433832	1	83	theme	polymer-based	164:176	arg1	sutures					178:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures	156:184	Natural polymer-based sutures have attractive cytocompatibility and degradability in surgical operations.					
36433832	8	84	from	promising	1565:1573	arg1	operations					1587:1596	surgical operations	1578:1596	surgical operations	1578:1596	Hence, the CGG/ACNF suture with a simple preparation method and excellent application properties is promising in surgical operations.					
35676493	8	0	theme	cell	1095:1098	arg1	viability					1100:1108	cell viability	1095:1108	cell viability	1095:1108	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	1	1	theme	work	158:161	arg1	objective					140:148	The objective	136:148	The objective of this work	136:161	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	8	2	dep	S.	1042:1043	arg1	cerevisiae					1045:1054	cerevisiae	1045:1054	cerevisiae	1045:1054	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	10	3	theme	yeasts	1415:1420	arg1	microencapsulation					1393:1410	the microencapsulation	1389:1410	the microencapsulation of yeasts	1389:1420	The study showed that maltodextrin as a wall material was efficient in the microencapsulation of yeasts.					
35676493	7	4	theme	infrared	900:907	arg1	analysis					922:929	Fourier-transform infrared spectroscopy analysis	882:929	Fourier-transform infrared spectroscopy analysis	882:929	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	8	5	from	increase	1083:1090	arg1	viability					1100:1108	cell viability	1095:1108	cell viability	1095:1108	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	2	6	with	maltodextrin	421:432	arg1	sucrose					465:471	sucrose	465:471	sucrose	465:471	The yeasts (109 CFU mL-1) were microencapsulated separately using maltodextrin (15%), maltodextrin (15%) with sucrose (2%), or maltose (2%) as wall material.					
35676493	7	7	theme	spectroscopy	909:920	arg1	analysis					922:929	Fourier-transform infrared spectroscopy analysis	882:929	Fourier-transform infrared spectroscopy analysis	882:929	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	0	8	dep	CCMA	125:128	arg1	Microencapsulation					0:17	Microencapsulation	0:17	Microencapsulation by spray drying of coffee epiphytic yeasts	0:60	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	11	9	theme	maltose	1453:1459	arg1	incorporation					1461:1473	maltose incorporation	1453:1473	maltose incorporation	1453:1473	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	9	10	theme	13.5	1260:1263	arg1	%					1264:1264	%	1264:1264	%	1264:1264	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	7	11	theme	spectra	979:985	arg1	footprints					987:996	typical spectra footprints	971:996	typical spectra footprints of maltodextrin	971:1012	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	11	12	theme	CCMA	1521:1524	arg1	0543					1526:1529	S. cerevisiae CCMA 0543	1507:1529	S. cerevisiae CCMA 0543	1507:1529	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	9	13	theme	%	1264:1264	arg1	increase					1266:1273	a 13.5% increase	1258:1273	a 13.5% increase in cell viability using only maltodextrin	1258:1315	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	7	14	theme	Fourier-transform	882:898	arg1	analysis					922:929	Fourier-transform infrared spectroscopy analysis	882:929	Fourier-transform infrared spectroscopy analysis	882:929	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	0	15	dep	Torulaspora	101:111	arg1	delbrueckii					113:123	Torulaspora delbrueckii	101:123	Torulaspora delbrueckii	101:123	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	10	16	from	efficient	1376:1384	arg1	microencapsulation					1393:1410	the microencapsulation	1389:1410	the microencapsulation of yeasts	1389:1420	The study showed that maltodextrin as a wall material was efficient in the microencapsulation of yeasts.					
35676493	2	17	with	maltose	482:488	arg1	sucrose					465:471	sucrose	465:471	sucrose	465:471	The yeasts (109 CFU mL-1) were microencapsulated separately using maltodextrin (15%), maltodextrin (15%) with sucrose (2%), or maltose (2%) as wall material.					
35676493	9	18	from	increase	1266:1273	arg1	viability					1283:1291	cell viability	1278:1291	cell viability using only maltodextrin	1278:1315	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	8	19	theme	storage	1033:1039	arg1	6 months					1021:1028	6 months	1021:1028	6 months of storage	1021:1039	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	11	20	theme	0543	1526:1529	arg1	viability					1494:1502	the cell viability	1485:1502	the cell viability of S. cerevisiae CCMA 0543	1485:1529	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	9	21	theme	cell	1278:1281	arg1	viability					1283:1291	cell viability	1278:1291	cell viability using only maltodextrin	1278:1315	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	10	22	theme	wall	1358:1361	arg1	material					1363:1370	a wall material	1356:1370	a wall material	1356:1370	The study showed that maltodextrin as a wall material was efficient in the microencapsulation of yeasts.					
35676493	1	23	theme	microencapsulation	183:200	arg1	feasibility					202:212	the microencapsulation feasibility	179:212	the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material	179:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	1	24	theme	different	299:307	arg1	compositions					309:320	three different compositions	293:320	three different compositions of wall material	293:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	2	25	theme	wall	498:501	arg1	material					503:510	wall material	498:510	wall material	498:510	The yeasts (109 CFU mL-1) were microencapsulated separately using maltodextrin (15%), maltodextrin (15%) with sucrose (2%), or maltose (2%) as wall material.					
35676493	11	26	theme	cell	1489:1492	arg1	viability					1494:1502	the cell viability	1485:1502	the cell viability of S. cerevisiae CCMA 0543	1485:1529	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	4	27	theme	microcapsules	673:685	arg1	viability					615:623	cell viability	610:623	cell viability after spray drying	610:642	The yield, cell viability after spray drying, and characterization of the microcapsules were performed.					
35676493	4	27	theme	microcapsules	673:685	arg1	characterization					649:664	characterization	649:664	characterization of the microcapsules	649:685	The yield, cell viability after spray drying, and characterization of the microcapsules were performed.					
35676493	4	27	theme	microcapsules	673:685	arg1	yield					603:607	The yield	599:607	The yield	599:607	The yield, cell viability after spray drying, and characterization of the microcapsules were performed.					
35676493	0	28	theme	spray	22:26	arg1	drying					28:33	spray drying	22:33	spray drying of coffee epiphytic yeasts	22:60	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	10	29	from	microencapsulation	1393:1410	arg1	efficient					1376:1384	efficient	1376:1384	efficient	1376:1384	The study showed that maltodextrin as a wall material was efficient in the microencapsulation of yeasts.					
35676493	0	30	dep	Saccharomyces	62:74	arg1	cerevisiae					76:85	cerevisiae	76:85	cerevisiae	76:85	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	0	31	theme	coffee	38:43	arg1	yeasts					55:60	coffee epiphytic yeasts	38:60	coffee epiphytic yeasts	38:60	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	9	32	theme	only	1299:1302	arg1	maltodextrin					1304:1315	only maltodextrin	1299:1315	only maltodextrin	1299:1315	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	8	33	theme	CCMA	1056:1059	arg1	0543					1061:1064	S. cerevisiae CCMA 0543	1042:1064	S. cerevisiae CCMA 0543	1042:1064	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	1	34	dep	Torulaspora	256:266	arg1	delbrueckii					268:278	Torulaspora delbrueckii	256:278	Torulaspora delbrueckii	256:278	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	1	35	theme	wall	325:328	arg1	material					330:337	wall material	325:337	wall material	325:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	11	36	theme	S.	1507:1508	arg1	0543					1526:1529	S. cerevisiae CCMA 0543	1507:1529	S. cerevisiae CCMA 0543	1507:1529	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	1	37	dep	CCMA	242:245	arg1	CCMA					280:283	CCMA	280:283	CCMA	280:283	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	7	38	theme	typical	971:977	arg1	footprints					987:996	typical spectra footprints	971:996	typical spectra footprints of maltodextrin	971:1012	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	3	39	dep	temperatures	571:582	arg1	25 °C					591:595	25 °C	591:595	25 °C	591:595	The viability was evaluated for 6 months at two different temperatures (7 and 25 °C).					
35676493	3	39	dep	temperatures	571:582	arg1	7					585:585	7	585:585	7	585:585	The viability was evaluated for 6 months at two different temperatures (7 and 25 °C).					
35676493	0	40	theme	yeasts	55:60	arg1	drying					28:33	spray drying	22:33	spray drying of coffee epiphytic yeasts	22:60	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	1	41	theme	material	330:337	arg1	compositions					309:320	three different compositions	293:320	three different compositions of wall material	293:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	7	42	theme	maltodextrin	1001:1012	arg1	footprints					987:996	typical spectra footprints	971:996	typical spectra footprints of maltodextrin	971:1012	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	8	43	theme	%	1081:1081	arg1	increase					1083:1090	a 10.8% increase	1075:1090	a 10.8% increase in cell viability	1075:1108	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	2	44	with	maltodextrin	441:452	arg1	sucrose					465:471	sucrose	465:471	sucrose	465:471	The yeasts (109 CFU mL-1) were microencapsulated separately using maltodextrin (15%), maltodextrin (15%) with sucrose (2%), or maltose (2%) as wall material.					
35676493	0	45	theme	epiphytic	45:53	arg1	yeasts					55:60	coffee epiphytic yeasts	38:60	coffee epiphytic yeasts	38:60	Microencapsulation by spray drying of coffee epiphytic yeasts Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684.					
35676493	8	46	theme	S.	1042:1043	arg1	0543					1061:1064	S. cerevisiae CCMA 0543	1042:1064	S. cerevisiae CCMA 0543	1042:1064	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	1	47	from	feasibility	202:212	arg1	compositions					309:320	three different compositions	293:320	three different compositions of wall material	293:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	4	48	theme	spray	631:635	arg1	drying					637:642	spray drying	631:642	spray drying	631:642	The yield, cell viability after spray drying, and characterization of the microcapsules were performed.					
35676493	8	49	theme	10.8	1077:1080	arg1	%					1081:1081	%	1081:1081	%	1081:1081	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	3	50	theme	different	561:569	arg1	temperatures					571:582	two different temperatures	557:582	two different temperatures (7 and 25 °C)	557:596	The viability was evaluated for 6 months at two different temperatures (7 and 25 °C).					
35676493	1	51	dep	Saccharomyces	217:229	arg1	cerevisiae					231:240	cerevisiae	231:240	cerevisiae	231:240	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	1	52	theme	CCMA	242:245	arg1	feasibility					202:212	the microencapsulation feasibility	179:212	the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material	179:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
35676493	9	53	theme	T.	1224:1225	arg1	0684					1244:1247	T. delbrueckii CCMA 0684	1224:1247	T. delbrueckii CCMA 0684	1224:1247	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	9	54	theme	delbrueckii	1227:1237	arg1	0684					1244:1247	T. delbrueckii CCMA 0684	1224:1247	T. delbrueckii CCMA 0684	1224:1247	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	7	55	theme	microencapsulated	936:952	arg1	yeasts					954:959	all microencapsulated yeasts	932:959	all microencapsulated yeasts	932:959	Regarding Fourier-transform infrared spectroscopy analysis, all microencapsulated yeasts presented typical spectra footprints of maltodextrin.					
35676493	4	56	theme	cell	610:613	arg1	viability					615:623	cell viability	610:623	cell viability after spray drying	610:642	The yield, cell viability after spray drying, and characterization of the microcapsules were performed.					
35676493	5	57	theme	cell	725:728	arg1	viability					730:738	cell viability	725:738	cell viability	725:738	Results indicate that cell viability ranged between 94.06 and 97.97%.					
35676493	9	58	theme	CCMA	1239:1242	arg1	0684					1244:1247	T. delbrueckii CCMA 0684	1224:1247	T. delbrueckii CCMA 0684	1224:1247	However, T. delbrueckii CCMA 0684 obtained a 13.5% increase in cell viability using only maltodextrin.					
35676493	8	59	theme	wall	1145:1148	arg1	material					1150:1157	wall material	1145:1157	wall material compared to maltodextrin and maltodextrin with sucrose	1145:1212	After 6 months of storage, S. cerevisiae CCMA 0543 obtained a 10.8% increase in cell viability using maltodextrin with maltose as wall material compared to maltodextrin and maltodextrin with sucrose.					
35676493	11	60	dep	S.	1507:1508	arg1	cerevisiae					1510:1519	cerevisiae	1510:1519	cerevisiae	1510:1519	It is possible to assume that maltose incorporation increased the cell viability of S. cerevisiae CCMA 0543 during storage.					
35676493	1	61	theme	Torulaspora	256:266	arg1	feasibility					202:212	the microencapsulation feasibility	179:212	the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material	179:337	The objective of this work was to evaluate the microencapsulation feasibility of Saccharomyces cerevisiae CCMA 0543 and Torulaspora delbrueckii CCMA 0684 in three different compositions of wall material by spray-dryer.					
36239303	7	0	theme	bile	1411:1414	arg1	acid					1416:1419	bile acid	1411:1419	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	6	1	theme	infrared	1015:1022	arg1	spectroscopy					1024:1035	infrared spectroscopy	1015:1035	infrared spectroscopy	1015:1035	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	8	2	from	SDF	1550:1552	arg1	CSR					1557:1559	CSR	1557:1559	CSR	1557:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	7	3	theme	inhibition	1386:1395	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	8	4	from	modification	1534:1545	arg1	CSR					1557:1559	CSR	1557:1559	CSR	1557:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	3	5	theme	degrading	499:507	arg1	YC49					516:519	the cellulose degrading fungus YC49	485:519	the cellulose degrading fungus YC49	485:519	To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.					
36239303	5	6	theme	endowed	813:819	arg1	F-SDF					821:825	that fermentation endowed F-SDF	795:825	that fermentation endowed F-SDF	795:825	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	7	7	theme	pancreatic	1368:1377	arg1	lipase					1379:1384	pancreatic lipase	1368:1384	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	1	8	from	seed	249:252	arg1	extraction					224:233	edible oil extraction	213:233	edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	213:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	0	9	theme	cellulose	123:131	arg1	YC49					150:153	a cellulose degrading fungus YC49	121:153	a cellulose degrading fungus YC49	121:153	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	1	10	theme	main	191:194	arg1	by-product					196:205	the main by-product	187:205	the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	187:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	10	theme	main	191:194	arg1	residue					170:176	Camellia seed residue	156:176	Camellia seed residue (CSR)	156:182	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	7	11	theme	cholesterol	1335:1345	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	4	12	theme	in	629:630	arg1	properties					652:661	in vitro hypolipidemic properties	629:661	in vitro hypolipidemic properties	629:661	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	0	13	theme	fungus	143:148	arg1	YC49					150:153	a cellulose degrading fungus YC49	121:153	a cellulose degrading fungus YC49	121:153	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	8	14	from	component	1618:1626	arg1	foods					1642:1646	functional foods	1631:1646	functional foods	1631:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	4	15	theme	hypolipidemic	638:650	arg1	properties					652:661	in vitro hypolipidemic properties	629:661	in vitro hypolipidemic properties	629:661	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	8	16	from	CSR	1557:1559	arg1	modification					1534:1545	the fermentation modification	1517:1545	the fermentation modification of SDF in CSR	1517:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	7	17	from	improvements	1195:1206	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	properties					1225:1234	hydration properties	1215:1234	hydration properties	1215:1234	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	17	from	improvements	1195:1206	arg1	activities					1254:1263	hypolipidemic activities	1240:1263	hypolipidemic activities	1240:1263	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	18	theme	oil	1311:1313	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	3	19	used	used	538:541	arg2	YC49					516:519	the cellulose degrading fungus YC49	485:519	the cellulose degrading fungus YC49	485:519	To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.					
36239303	1	20	theme	soluble	295:301	arg1	fiber					311:315	soluble dietary fiber	295:315	soluble dietary fiber (SDF)	295:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	20	theme	soluble	295:301	arg1	SDF					318:320	SDF	318:320	SDF	318:320	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	5	21	theme	weight	748:753	arg1	distribution					755:766	molecular weight distribution	738:766	molecular weight distribution	738:766	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	0	22	theme	dietary	79:85	arg1	fiber					87:91	soluble dietary fiber	71:91	soluble dietary fiber in camellia seed residue	71:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	1	23	theme	fiber	311:315	arg1	source					285:290	a potential low-cost source	264:290	a potential low-cost source of soluble dietary fiber (SDF)	264:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	23	theme	fiber	311:315	arg1	seed					249:252	seed	249:252	seed	249:252	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	24	theme	Camellia	156:163	arg1	by-product					196:205	the main by-product	187:205	the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	187:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	24	theme	Camellia	156:163	arg1	CSR					179:181	CSR	179:181	CSR	179:181	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	24	theme	Camellia	156:163	arg1	residue					170:176	Camellia seed residue	156:176	Camellia seed residue (CSR)	156:182	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	2	25	from	application	393:403	arg1	industry					428:435	the food industry	419:435	the food industry	419:435	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	7	26	dep	properties	1225:1234	arg1	the					1211:1213	the	1211:1213	the	1211:1213	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	8	27	used	used	1489:1492	arg2	strain					1506:1511	an ideal strain	1497:1511	an ideal strain	1497:1511	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	27	used	used	1489:1492	arg2	potential					1580:1588	the potential to serve as a hypolipidemic component in functional foods	1576:1646	the potential to serve as a hypolipidemic component in functional foods	1576:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	27	used	used	1489:1492	arg2	YC49					1475:1478	YC49	1475:1478	YC49	1475:1478	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	6	28	dep	Fourier	997:1003	arg1	transform					1005:1013	transform	1005:1013	transform infrared spectroscopy	1005:1035	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	0	29	theme	seed	105:108	arg1	residue					110:116	camellia seed residue	96:116	camellia seed residue	96:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	5	30	theme	molecular	912:920	arg1	weight					922:927	smaller molecular weight	904:927	smaller molecular weight	904:927	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	7	31	theme	holding	1293:1299	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	2	32	theme	further	385:391	arg1	application					393:403	the further application	381:403	the further application of CSR SDF in the food industry	381:435	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	4	33	theme	SDF	670:672	arg1	properties					652:661	in vitro hypolipidemic properties	629:661	in vitro hypolipidemic properties	629:661	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	4	33	theme	SDF	670:672	arg1	structure					615:623	physicochemical structure	599:623	physicochemical structure	599:623	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	0	34	theme	physicochemical	14:28	arg1	properties					57:66	the physicochemical and in vitro hypolipidemic properties	10:66	the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue	10:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	5	35	theme	lower	883:887	arg1	crystallinity					889:901	lower crystallinity	883:901	lower crystallinity	883:901	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	7	36	theme	CSR	1268:1270	arg1	SDF					1272:1274	CSR SDF	1268:1274	CSR SDF	1268:1274	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	2	37	theme	functional	353:362	arg1	properties					364:373	functional properties	353:373	functional properties	353:373	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	0	38	theme	in	34:35	arg1	properties					57:66	the physicochemical and in vitro hypolipidemic properties	10:66	the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue	10:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	1	39	theme	potential	266:274	arg1	source					285:290	a potential low-cost source	264:290	a potential low-cost source of soluble dietary fiber (SDF)	264:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	39	theme	potential	266:274	arg1	seed					249:252	seed	249:252	seed	249:252	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	7	40	theme	SDF	1272:1274	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	properties					1225:1234	hydration properties	1215:1234	hydration properties	1215:1234	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	40	theme	SDF	1272:1274	arg1	activities					1254:1263	hypolipidemic activities	1240:1263	hypolipidemic activities	1240:1263	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	2	41	theme	SDF	412:414	arg1	application					393:403	the further application	381:403	the further application of CSR SDF in the food industry	381:435	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	5	42	theme	X-ray	719:723	arg1	diffraction					725:735	X-ray diffraction	719:735	X-ray diffraction	719:735	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	0	43	dep	in	34:35	arg1	vitro					37:41	vitro	37:41	vitro	37:41	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	8	44	theme	SDF	1550:1552	arg1	modification					1534:1545	the fermentation modification	1517:1545	the fermentation modification of SDF in CSR	1517:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	45	theme	hypolipidemic	1240:1252	arg1	activities					1254:1263	hypolipidemic activities	1240:1263	hypolipidemic activities	1240:1263	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	6	46	theme	monosaccharide	966:979	arg1	composition					981:991	monosaccharide composition	966:991	monosaccharide composition	966:991	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	1	47	theme	edible	213:218	arg1	extraction					224:233	edible oil extraction	213:233	edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	213:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	3	48	from	SDF	553:555	arg1	CSR					560:562	CSR	560:562	CSR	560:562	To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.					
36239303	8	49	theme	functional	1631:1640	arg1	foods					1642:1646	functional foods	1631:1646	functional foods	1631:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	7	50	theme	acid	1416:1419	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	1	51	theme	seed	165:168	arg1	by-product					196:205	the main by-product	187:205	the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	187:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	51	theme	seed	165:168	arg1	CSR					179:181	CSR	179:181	CSR	179:181	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	51	theme	seed	165:168	arg1	residue					170:176	Camellia seed residue	156:176	Camellia seed residue (CSR)	156:182	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	0	52	theme	hypolipidemic	43:55	arg1	properties					57:66	the physicochemical and in vitro hypolipidemic properties	10:66	the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue	10:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	7	53	theme	binding	1421:1427	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	5	54	theme	Scanning	689:696	arg1	microscopy					707:716	Scanning electron microscopy	689:716	Scanning electron microscopy	689:716	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	3	55	theme	cellulose	489:497	arg1	YC49					516:519	the cellulose degrading fungus YC49	485:519	the cellulose degrading fungus YC49	485:519	To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.					
36239303	0	56	from	fiber	87:91	arg1	residue					110:116	camellia seed residue	96:116	camellia seed residue	96:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	6	57	theme	group	1109:1113	arg1	types					1115:1119	functional group types	1098:1119	functional group types	1098:1119	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	0	58	theme	degrading	133:141	arg1	YC49					150:153	a cellulose degrading fungus YC49	121:153	a cellulose degrading fungus YC49	121:153	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	5	59	theme	flow	772:775	arg1	properties					777:786	flow properties	772:786	flow properties	772:786	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	3	60	theme	fungus	509:514	arg1	YC49					516:519	the cellulose degrading fungus YC49	485:519	the cellulose degrading fungus YC49	485:519	To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.					
36239303	0	61	from	residue	110:116	arg1	properties					57:66	the physicochemical and in vitro hypolipidemic properties	10:66	the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue	10:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	7	62	theme	adsorption	1347:1356	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	0	63	theme	soluble	71:77	arg1	fiber					87:91	soluble dietary fiber	71:91	soluble dietary fiber in camellia seed residue	71:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	8	64	mod	modification	1534:1545	arg1	SDF					1550:1552	SDF	1550:1552	SDF in CSR	1550:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	64	mod	modification	1534:1545	arg3	fermentation					1521:1532	the fermentation modification	1517:1545	the fermentation modification of SDF in CSR	1517:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	7	65	theme	retention	1315:1323	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	0	66	theme	fiber	87:91	arg1	properties					57:66	the physicochemical and in vitro hypolipidemic properties	10:66	the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue	10:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	1	67	theme	dietary	303:309	arg1	fiber					311:315	soluble dietary fiber	295:315	soluble dietary fiber (SDF)	295:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	67	theme	dietary	303:309	arg1	SDF					318:320	SDF	318:320	SDF	318:320	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	2	68	theme	food	423:426	arg1	industry					428:435	the food industry	419:435	the food industry	419:435	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	4	69	theme	physicochemical	599:613	arg1	structure					615:623	physicochemical structure	599:623	physicochemical structure	599:623	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	0	70	theme	camellia	96:103	arg1	residue					110:116	camellia seed residue	96:116	camellia seed residue	96:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	4	71	dep	structure	615:623	arg1	the					595:597	the	595:597	the	595:597	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	7	72	theme	lipase	1379:1384	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	0	73	from	properties	57:66	arg1	residue					110:116	camellia seed residue	96:116	camellia seed residue	96:116	Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.					
36239303	8	74	contain	has	1572:1574	arg2	potential					1580:1588	the potential to serve as a hypolipidemic component in functional foods	1576:1646	the potential to serve as a hypolipidemic component in functional foods	1576:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	74	contain	has	1572:1574	arg2	strain					1506:1511	an ideal strain	1497:1511	an ideal strain	1497:1511	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	74	contain	has	1572:1574	arg1	F-SDF					1566:1570	F-SDF	1566:1570	F-SDF	1566:1570	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	74	contain	has	1572:1574	arg2	YC49					1475:1478	YC49	1475:1478	YC49	1475:1478	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	6	75	theme	monosaccharide	1067:1080	arg1	percentages					1082:1092	the monosaccharide percentages	1063:1092	the monosaccharide percentages	1063:1092	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	5	76	theme	smaller	904:910	arg1	weight					922:927	smaller molecular weight	904:927	smaller molecular weight	904:927	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	8	77	theme	ideal	1500:1504	arg1	strain					1506:1511	an ideal strain	1497:1511	an ideal strain	1497:1511	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	77	theme	ideal	1500:1504	arg1	potential					1580:1588	the potential to serve as a hypolipidemic component in functional foods	1576:1646	the potential to serve as a hypolipidemic component in functional foods	1576:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	8	77	theme	ideal	1500:1504	arg1	YC49					1475:1478	YC49	1475:1478	YC49	1475:1478	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	2	78	theme	lower	337:341	arg1	yield					343:347	the lower yield	333:347	the lower yield	333:347	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	5	79	theme	porous	860:865	arg1	microstructure					867:880	a more porous microstructure	853:880	a more porous microstructure	853:880	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	7	80	theme	water	1287:1291	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	5	81	theme	molecular	738:746	arg1	distribution					755:766	molecular weight distribution	738:766	molecular weight distribution	738:766	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	4	82	dep	in	629:630	arg1	vitro					632:636	vitro	632:636	vitro	632:636	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	6	83	theme	Fourier	997:1003	arg1	results					955:961	The results	951:961	The results of monosaccharide composition and Fourier transform infrared spectroscopy	951:1035	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	8	84	theme	fermentation	1521:1532	arg1	modification					1534:1545	the fermentation modification	1517:1545	the fermentation modification of SDF in CSR	1517:1559	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	4	85	theme	CSR	666:668	arg1	SDF					670:672	CSR SDF	666:672	CSR SDF	666:672	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	5	86	theme	electron	698:705	arg1	microscopy					707:716	Scanning electron microscopy	689:716	Scanning electron microscopy	689:716	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	6	87	theme	composition	981:991	arg1	results					955:961	The results	951:961	The results of monosaccharide composition and Fourier transform infrared spectroscopy	951:1035	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	4	88	with	fermentation	571:582	arg1	YC49					589:592	YC49	589:592	YC49	589:592	After fermentation with YC49, the physicochemical structure and in vitro hypolipidemic properties of CSR SDF were improved.					
36239303	1	89	theme	low-cost	276:283	arg1	source					285:290	a potential low-cost source	264:290	a potential low-cost source of soluble dietary fiber (SDF)	264:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	1	89	theme	low-cost	276:283	arg1	seed					249:252	seed	249:252	seed	249:252	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
36239303	6	90	theme	functional	1098:1107	arg1	types					1115:1119	functional group types	1098:1119	functional group types	1098:1119	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	2	91	theme	CSR	408:410	arg1	SDF					412:414	CSR SDF	408:414	CSR SDF	408:414	However, the lower yield and functional properties limit the further application of CSR SDF in the food industry.					
36239303	6	92	from	differences	1048:1058	arg1	percentages					1082:1092	the monosaccharide percentages	1063:1092	the monosaccharide percentages	1063:1092	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	6	92	from	differences	1048:1058	arg1	types					1115:1119	functional group types	1098:1119	functional group types	1098:1119	The results of monosaccharide composition and Fourier transform infrared spectroscopy pointed to differences in the monosaccharide percentages and functional group types between CK-SDF (control) and F-SDF.					
36239303	8	93	theme	hypolipidemic	1604:1616	arg1	component					1618:1626	a hypolipidemic component	1602:1626	a hypolipidemic component in functional foods	1602:1646	Overall, the results indicated that YC49 could be used as an ideal strain for the fermentation modification of SDF in CSR, and F-SDF has the potential to serve as a hypolipidemic component in functional foods.					
36239303	5	94	theme	higher	933:938	arg1	viscosity					940:948	higher viscosity	933:948	higher viscosity	933:948	Scanning electron microscopy, X-ray diffraction, molecular weight distribution and flow properties showed that fermentation endowed F-SDF (after fermentation) with a more porous microstructure, lower crystallinity, smaller molecular weight and higher viscosity.					
36239303	7	95	theme	hydration	1215:1223	arg1	capacity					1397:1404	pancreatic lipase inhibition capacity	1368:1404	pancreatic lipase inhibition capacity	1368:1404	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	95	theme	hydration	1215:1223	arg1	capacity					1301:1308	water holding capacity	1287:1308	water holding capacity	1287:1308	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	95	theme	hydration	1215:1223	arg1	capacity					1429:1436	bile acid binding capacity	1411:1436	bile acid binding capacity	1411:1436	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	95	theme	hydration	1215:1223	arg1	properties					1225:1234	hydration properties	1215:1234	hydration properties	1215:1234	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	95	theme	hydration	1215:1223	arg1	capacity					1358:1365	cholesterol adsorption capacity	1335:1365	cholesterol adsorption capacity	1335:1365	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	7	95	theme	hydration	1215:1223	arg1	capacity					1325:1332	oil retention capacity	1311:1332	oil retention capacity	1311:1332	These alterations combined to achieve improvements in the hydration properties and hypolipidemic activities of CSR SDF, including water holding capacity, oil retention capacity, cholesterol adsorption capacity, pancreatic lipase inhibition capacity, and bile acid binding capacity.					
36239303	1	96	theme	oil	220:222	arg1	extraction					224:233	edible oil extraction	213:233	edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF)	213:321	Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF).					
35628421	7	0	theme	scattered	1399:1407	arg1	light					1409:1413	the coherent scattered light	1386:1413	the coherent scattered light	1386:1413	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	4	1	theme	contact	845:851	arg1	test					864:867	contact angle (CA) test	845:867	contact angle (CA) test	845:867	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	1	theme	contact	845:851	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	8	2	dep	color	1665:1669	arg1	them					1675:1678	them	1675:1678	them	1675:1678	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	8	3	theme	present	1525:1531	arg1	study					1533:1537	the present study	1521:1537	the present study	1521:1537	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	6	4	theme	free	1217:1220	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	4	theme	free	1217:1220	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	4	theme	free	1217:1220	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	5	5	contain	possessed	933:941	arg2	MPa					976:978	55.17 MPa	970:978	55.17 MPa	970:978	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	5	contain	possessed	933:941	arg2	strength					960:967	a higher tensile strength	943:967	a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	943:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	5	contain	possessed	933:941	arg1	SCFs					928:931	the obtained SCFs	915:931	the obtained SCFs	915:931	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	6	6	theme	low	1205:1207	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	6	theme	low	1205:1207	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	6	theme	low	1205:1207	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	8	7	theme	SCFs	1607:1610	arg1	strength					1574:1581	mechanical strength	1563:1581	mechanical strength	1563:1581	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	8	7	theme	SCFs	1607:1610	arg1	resistance					1593:1602	water resistance	1587:1602	water resistance	1587:1602	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	1	8	theme	energy	256:261	arg1	consumption					263:273	energy consumption	256:273	energy consumption	256:273	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	9	theme	alternative	154:164	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	3	10	with	SCFs	412:415	arg1	super-hydrophobicity					422:441	super-hydrophobicity	422:441	super-hydrophobicity	422:441	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	3	10	with	SCFs	412:415	arg1	colors					468:473	excellent structural colors	447:473	excellent structural colors	447:473	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	4	11	theme	electron	693:700	arg1	SEM					714:716	SEM	714:716	SEM	714:716	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	11	theme	electron	693:700	arg1	Fourier					720:726	Fourier	720:726	Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	720:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	11	theme	electron	693:700	arg1	microscope					702:711	scanning electron microscope	684:711	scanning electron microscope (SEM)	684:717	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	1	12	theme	materials	176:184	arg1	one					138:140	one	138:140	one	138:140	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	12	theme	materials	176:184	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	12	theme	materials	176:184	arg1	films					117:121	The starch composite films	96:121	The starch composite films (SCFs)	96:128	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	6	13	dep	angle	1242:1246	arg1	the					1230:1232	the	1230:1232	the	1230:1232	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	8	14	from	strategy	1509:1516	arg1	study					1533:1537	the present study	1521:1537	the present study	1521:1537	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	5	15	theme	formed	999:1004	arg1	bonds					1024:1028	the formed abundant hydrogen bonds	995:1028	the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	995:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	2	16	theme	weak	285:288	arg1	stability					301:309	weak mechanical stability	285:309	weak mechanical stability	285:309	However, weak mechanical stability, water resistance, and dyeability has hindered the application of SCFs.					
35628421	8	17	theme	friendly	1649:1656	arg1	way					1658:1660	an environmentally friendly way	1630:1660	an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films	1630:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	1	18	theme	petroleum	189:197	arg1	films					213:217	petroleum based plastic films	189:217	petroleum based plastic films	189:217	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	4	19	theme	various	658:664	arg1	test					864:867	contact angle (CA) test	845:867	contact angle (CA) test	845:867	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	19	theme	various	658:664	arg1	test					839:842	a tensile test	829:842	a tensile test	829:842	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	19	theme	various	658:664	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	19	theme	various	658:664	arg1	test					885:888	an optical test	874:888	an optical test	874:888	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	5	20	theme	hydrogen	1015:1022	arg1	bonds					1024:1028	the formed abundant hydrogen bonds	995:1028	the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	995:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	1	21	theme	plastic	205:211	arg1	films					213:217	petroleum based plastic films	189:217	petroleum based plastic films	189:217	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	6	22	theme	contact	1234:1240	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	22	theme	contact	1234:1240	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	8	23	dep	strength	1574:1581	arg1	the					1559:1561	the	1559:1561	the	1559:1561	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	4	24	theme	infrared	738:745	arg1	FT-IR					761:765	FT-IR	761:765	FT-IR	761:765	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	24	theme	infrared	738:745	arg1	spectroscopy					747:758	infrared spectroscopy	738:758	infrared spectroscopy (FT-IR)	738:766	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	24	theme	infrared	738:745	arg1	diffraction					775:785	X-ray diffraction	769:785	X-ray diffraction (XRD)	769:791	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	24	theme	infrared	738:745	arg1	analysis					813:820	thermo-gravimetric analysis	794:820	thermo-gravimetric analysis (TGA)	794:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	1	25	theme	composite	107:115	arg1	one					138:140	one	138:140	one	138:140	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	25	theme	composite	107:115	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	25	theme	composite	107:115	arg1	SCFs					124:127	SCFs	124:127	SCFs	124:127	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	25	theme	composite	107:115	arg1	films					117:121	The starch composite films	96:121	The starch composite films (SCFs)	96:128	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	7	26	theme	nanoparticles	1490:1502	arg1	diameters					1468:1476	the diameters	1464:1476	the diameters of the SiO2 nanoparticles	1464:1502	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	8	27	theme	water	1587:1591	arg1	resistance					1593:1602	water resistance	1587:1602	water resistance	1587:1602	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	0	28	theme	Vivid	71:75	arg1	Colors					88:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	5	29	theme	starch	1066:1071	arg1	alcohol					1105:1111	polyvinyl alcohol	1095:1111	polyvinyl alcohol	1095:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	29	theme	starch	1066:1071	arg1	chains					1052:1057	the molecular chains	1038:1057	the molecular chains of the starch	1038:1071	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	29	theme	starch	1066:1071	arg1	fiber					1084:1088	cellulose fiber	1074:1088	cellulose fiber	1074:1088	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	8	30	theme	application	1707:1717	arg1	potential					1719:1727	unprecedented application potential	1693:1727	unprecedented application potential	1693:1727	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	8	31	theme	films	1776:1780	arg1	materials					1742:1750	packaging materials	1732:1750	packaging materials of the starch composite films	1732:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	4	32	theme	X-ray	769:773	arg1	XRD					788:790	XRD	788:790	XRD	788:790	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	32	theme	X-ray	769:773	arg1	diffraction					775:785	X-ray diffraction	769:785	X-ray diffraction (XRD)	769:791	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	32	theme	X-ray	769:773	arg1	spectroscopy					747:758	infrared spectroscopy	738:758	infrared spectroscopy (FT-IR)	738:766	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	3	33	from	arrays	570:575	arg1	surface					584:590	the surface	580:590	the surface of SCFs	580:598	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	6	34	with	nanostructure	1134:1146	arg1	surface					1159:1165	rough surface	1153:1165	rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively	1153:1316	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	5	35	theme	molecular	1042:1050	arg1	chains					1052:1057	the molecular chains	1038:1057	the molecular chains of the starch	1038:1071	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	3	36	theme	robust	405:410	arg1	SCFs					412:415	a bioinspired robust SCFs	391:415	a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors	391:473	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	0	37	theme	Biomimetic	0:9	arg1	Films					35:39	Biomimetic Robust Starch Composite Films	0:39	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.	0:94	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	5	38	theme	polyvinyl	1095:1103	arg1	alcohol					1105:1111	polyvinyl alcohol	1095:1111	polyvinyl alcohol	1095:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	1	39	theme	starch	100:105	arg1	one					138:140	one	138:140	one	138:140	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	39	theme	starch	100:105	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	39	theme	starch	100:105	arg1	SCFs					124:127	SCFs	124:127	SCFs	124:127	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	39	theme	starch	100:105	arg1	films					117:121	The starch composite films	96:121	The starch composite films (SCFs)	96:128	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	3	40	theme	structural	457:466	arg1	colors					468:473	excellent structural colors	447:473	excellent structural colors	447:473	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	0	41	theme	Starch	18:23	arg1	Films					35:39	Biomimetic Robust Starch Composite Films	0:39	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.	0:94	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	7	42	theme	visible	1438:1444	arg1	regions					1446:1452	the visible regions	1434:1452	the visible regions	1434:1452	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	5	43	theme	cellulose	1074:1082	arg1	fiber					1084:1088	cellulose fiber	1074:1088	cellulose fiber	1074:1088	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	0	44	theme	Super-Hydrophobicity	46:65	arg1	Colors					88:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	6	45	mod	modified	1178:1185	arg1	surface					1159:1165	rough surface	1153:1165	rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively	1153:1316	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	45	mod	modified	1178:1185	arg3	materials					1190:1198	materials	1190:1198	materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively	1190:1316	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	7	46	theme	light	1409:1413	arg1	interference					1370:1381	the constructive interference	1353:1381	the constructive interference of the coherent scattered light	1353:1413	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	4	47	theme	thermo-gravimetric	794:811	arg1	spectroscopy					747:758	infrared spectroscopy	738:758	infrared spectroscopy (FT-IR)	738:766	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	47	theme	thermo-gravimetric	794:811	arg1	TGA					823:825	TGA	823:825	TGA	823:825	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	47	theme	thermo-gravimetric	794:811	arg1	analysis					813:820	thermo-gravimetric analysis	794:820	thermo-gravimetric analysis (TGA)	794:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	7	48	theme	coherent	1390:1397	arg1	light					1409:1413	the coherent scattered light	1386:1413	the coherent scattered light	1386:1413	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	5	49	theme	tensile	952:958	arg1	strength					960:967	a higher tensile strength	943:967	a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	943:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	49	theme	tensile	952:958	arg1	MPa					976:978	55.17 MPa	970:978	55.17 MPa	970:978	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	4	50	theme	designed	623:630	arg1	SCFs					632:635	the designed SCFs	619:635	the designed SCFs	619:635	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	8	51	theme	composite	1766:1774	arg1	films					1776:1780	the starch composite films	1755:1780	the starch composite films	1755:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	0	52	with	Films	35:39	arg1	Colors					88:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	1	53	theme	white	236:240	arg1	pollution					242:250	white pollution	236:250	white pollution	236:250	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	6	54	theme	surface	1209:1215	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	54	theme	surface	1209:1215	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	54	theme	surface	1209:1215	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	3	55	theme	amorphous	560:568	arg1	arrays					570:575	fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays	492:575	fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs	492:598	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	6	56	with	materials	1190:1198	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	56	with	materials	1190:1198	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	56	with	materials	1190:1198	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	7	57	theme	constructive	1357:1368	arg1	interference					1370:1381	the constructive interference	1353:1381	the constructive interference of the coherent scattered light	1353:1413	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	4	58	theme	angle	853:857	arg1	test					864:867	contact angle (CA) test	845:867	contact angle (CA) test	845:867	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	58	theme	angle	853:857	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	1	59	theme	best	149:152	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	1	60	theme	packaging	166:174	arg1	materials					176:184	the best alternative packaging materials	145:184	the best alternative packaging materials	145:184	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	4	61	theme	tensile	831:837	arg1	test					839:842	a tensile test	829:842	a tensile test	829:842	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	61	theme	tensile	831:837	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	62	theme	scanning	684:691	arg1	SEM					714:716	SEM	714:716	SEM	714:716	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	62	theme	scanning	684:691	arg1	Fourier					720:726	Fourier	720:726	Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	720:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	62	theme	scanning	684:691	arg1	microscope					702:711	scanning electron microscope	684:711	scanning electron microscope (SEM)	684:717	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	2	63	theme	mechanical	290:299	arg1	stability					301:309	weak mechanical stability	285:309	weak mechanical stability	285:309	However, weak mechanical stability, water resistance, and dyeability has hindered the application of SCFs.					
35628421	6	64	theme	sliding	1252:1258	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	64	theme	sliding	1252:1258	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	5	65	theme	abundant	1006:1013	arg1	bonds					1024:1028	the formed abundant hydrogen bonds	995:1028	the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	995:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	8	66	theme	environmentally	1633:1647	arg1	way					1658:1660	an environmentally friendly way	1630:1660	an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films	1630:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	1	67	theme	based	199:203	arg1	films					213:217	petroleum based plastic films	189:217	petroleum based plastic films	189:217	The starch composite films (SCFs) will be one of the best alternative packaging materials to petroleum based plastic films, which mitigates white pollution and energy consumption.					
35628421	4	68	theme	optical	877:883	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	68	theme	optical	877:883	arg1	test					885:888	an optical test	874:888	an optical test	874:888	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	3	69	theme	SCFs	595:598	arg1	surface					584:590	the surface	580:590	the surface of SCFs	580:598	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	4	70	theme	CA	860:861	arg1	test					864:867	contact angle (CA) test	845:867	contact angle (CA) test	845:867	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	4	70	theme	CA	860:861	arg1	methods					666:672	various methods	658:672	various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	658:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	6	71	theme	rough	1153:1157	arg1	surface					1159:1165	rough surface	1153:1165	rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively	1153:1316	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	7	72	theme	SiO2	1485:1488	arg1	nanoparticles					1490:1502	the SiO2 nanoparticles	1481:1502	the SiO2 nanoparticles	1481:1502	The colors which were produced by the constructive interference of the coherent scattered light could cover all of the visible regions by tuning the diameters of the SiO2 nanoparticles.					
35628421	0	73	theme	Structural	77:86	arg1	Colors					88:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Super-Hydrophobicity and Vivid Structural Colors	46:93	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	8	74	theme	unprecedented	1693:1705	arg1	potential					1719:1727	unprecedented application potential	1693:1727	unprecedented application potential	1693:1727	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	8	75	theme	starch	1759:1764	arg1	films					1776:1780	the starch composite films	1755:1780	the starch composite films	1755:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	6	76	theme	film	1273:1276	arg1	angle					1242:1246	contact angle	1234:1246	contact angle	1234:1246	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	76	theme	film	1273:1276	arg1	angle					1260:1264	sliding angle	1252:1264	sliding angle	1252:1264	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	76	theme	film	1273:1276	arg1	energy					1222:1227	low surface free energy	1205:1227	low surface free energy	1205:1227	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	6	77	dep	154°	1292:1295	arg1	up					1286:1287	up	1286:1287	up	1286:1287	Benefiting from the nanostructure with rough surface which were modified by materials with low surface free energy, the contact angle and sliding angle of the film reached up to 154° and 2°, respectively.					
35628421	5	78	theme	obtained	919:926	arg1	SCFs					928:931	the obtained SCFs	915:931	the obtained SCFs	915:931	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	2	79	theme	SCFs	377:380	arg1	application					362:372	the application	358:372	the application of SCFs	358:380	However, weak mechanical stability, water resistance, and dyeability has hindered the application of SCFs.					
35628421	0	80	theme	Robust	11:16	arg1	Films					35:39	Biomimetic Robust Starch Composite Films	0:39	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.	0:94	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	8	81	theme	packaging	1732:1740	arg1	materials					1742:1750	packaging materials	1732:1750	packaging materials of the starch composite films	1732:1780	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	0	82	theme	Composite	25:33	arg1	Films					35:39	Biomimetic Robust Starch Composite Films	0:39	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.	0:94	Biomimetic Robust Starch Composite Films with Super-Hydrophobicity and Vivid Structural Colors.					
35628421	4	83	dep	Fourier	720:726	arg1	transform					728:736	transform	728:736	transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA)	728:826	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
35628421	3	84	theme	bioinspired	393:403	arg1	SCFs					412:415	a bioinspired robust SCFs	391:415	a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors	391:473	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	3	85	theme	excellent	447:455	arg1	colors					468:473	excellent structural colors	447:473	excellent structural colors	447:473	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	3	86	theme	fiber-reinforcement	492:510	arg1	arrays					570:575	fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays	492:575	fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs	492:598	Herein, a bioinspired robust SCFs with super-hydrophobicity and excellent structural colors were prepared by fiber-reinforcement and assembling SiO2/Polydimethylsiloxane (PDMS) amorphous arrays on the surface of SCFs.					
35628421	2	87	theme	water	312:316	arg1	resistance					318:327	water resistance	312:327	water resistance	312:327	However, weak mechanical stability, water resistance, and dyeability has hindered the application of SCFs.					
35628421	8	88	theme	mechanical	1563:1572	arg1	strength					1574:1581	mechanical strength	1563:1581	mechanical strength	1563:1581	The strategy in the present study not only reinforces the mechanical strength and water resistance of SCFs but also provides an environmentally friendly way to color the them, which shows unprecedented application potential in packaging materials of the starch composite films.					
35628421	5	89	theme	higher	945:950	arg1	strength					960:967	a higher tensile strength	943:967	a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol	943:1111	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	5	89	theme	higher	945:950	arg1	MPa					976:978	55.17 MPa	970:978	55.17 MPa	970:978	The results showed that the obtained SCFs possessed a higher tensile strength (55.17 MPa) attributed to the formed abundant hydrogen bonds between the molecular chains of the starch, cellulose fiber, and polyvinyl alcohol.					
35628421	4	90	theme	SCFs	632:635	arg1	properties					605:614	The properties	601:614	The properties of the designed SCFs	601:635	The properties of the designed SCFs were investigated by various methods including scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), a tensile test, contact angle (CA) test, and an optical test.					
36948341	0	0	theme	stem	113:116	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	6	1	theme	alginate	1146:1153	arg1	composite					1167:1175	the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function	1142:1317	the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function	1142:1317	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	0	2	theme	adipose-derived	97:111	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	3	3	theme	cartilage	754:762	arg1	regeneration					764:775	cartilage regeneration	754:775	cartilage regeneration	754:775	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	4	4	theme	best	921:924	arg1	composition					926:936	the best composition	917:936	the best composition for encapsulated hASCs viability	917:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	1	5	theme	promising	181:189	arg1	strategy					191:198	a promising strategy	179:198	a promising strategy for cartilage tissue engineering	179:231	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	1	5	theme	promising	181:189	arg1	therapy					168:174	Stem cell therapy	158:174	Stem cell therapy	158:174	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	5	6	theme	better	1056:1061	arg1	viability					1068:1076	better cell viability	1056:1076	better cell viability	1056:1076	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	4	7	theme	encapsulated	942:953	arg1	viability					961:969	encapsulated hASCs viability	942:969	encapsulated hASCs viability	942:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	3	8	theme	hydrogel	595:602	arg1	scaffolds					604:612	The composite hydrogel scaffolds	581:612	The composite hydrogel scaffolds	581:612	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	5	9	theme	optimal	1006:1012	arg1	properties					1041:1050	optimal mechanical and rheological properties	1006:1050	optimal mechanical and rheological properties	1006:1050	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	5	10	theme	ECM	990:992	arg1	 w/v					982:985	4 % w/v	979:985	4 % w/v of ECM	979:992	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	7	11	theme	cartilage	1587:1595	arg1	engineering					1604:1614	cartilage tissue engineering	1587:1614	cartilage tissue engineering application	1587:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	3	12	from	conditions	666:675	arg1	proliferation					708:720	cell proliferation	703:720	cell proliferation	703:720	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	3	12	from	conditions	666:675	arg1	differentiation					727:741	differentiation	727:741	differentiation	727:741	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	3	12	from	conditions	666:675	arg1	properties					691:700	mechanical properties	680:700	mechanical properties	680:700	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	0	13	theme	tissue	138:143	arg1	engineering					145:155	cartilage tissue engineering	128:155	cartilage tissue engineering	128:155	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	6	14	theme	layered	1198:1204	arg1	hydrogel-nanofiber					1206:1223	layered hydrogel-nanofiber	1198:1223	different layered hydrogel-nanofiber (2, 3, and 5-layer) structures	1188:1254	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	6	15	theme	electrospun	1097:1107	arg1	layers					1121:1126	electrospun nanofibrous layers	1097:1126	electrospun nanofibrous layers	1097:1126	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	4	16	theme	ECM	836:838	arg1	powder					840:845	ECM powder	836:845	ECM powder	836:845	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	7	17	theme	optimum	1362:1368	arg1	features					1574:1581	promising features	1564:1581	promising features for cartilage tissue engineering application	1564:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	17	theme	optimum	1362:1368	arg1	structure					1332:1340	The 3-layer structure	1320:1340	The 3-layer structure	1320:1340	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	17	theme	optimum	1362:1368	arg1	scaffold					1388:1395	the optimum layered composite scaffold	1358:1395	the optimum layered composite scaffold	1358:1395	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	18	theme	composite	1378:1386	arg1	features					1574:1581	promising features	1564:1581	promising features for cartilage tissue engineering application	1564:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	18	theme	composite	1378:1386	arg1	structure					1332:1340	The 3-layer structure	1320:1340	The 3-layer structure	1320:1340	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	18	theme	composite	1378:1386	arg1	scaffold					1388:1395	the optimum layered composite scaffold	1358:1395	the optimum layered composite scaffold	1358:1395	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	0	19	theme	cartilage	128:136	arg1	engineering					145:155	cartilage tissue engineering	128:155	cartilage tissue engineering	128:155	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	2	20	theme	extracellular	493:505	arg1	ECM					515:517	ECM	515:517	ECM	515:517	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	20	theme	extracellular	493:505	arg1	matrix					507:512	extracellular matrix	493:512	extracellular matrix (ECM)	493:518	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	6	21	dep	hydrogel-nanofiber	1206:1223	arg1	2					1226:1226	2	1226:1226	2	1226:1226	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	6	21	dep	hydrogel-nanofiber	1206:1223	arg1	3					1229:1229	3	1229:1229	3	1229:1229	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	6	21	dep	hydrogel-nanofiber	1206:1223	arg1	5-layer					1236:1242	5-layer	1236:1242	5-layer	1236:1242	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	0	22	theme	sulfate/ECM	9:19	arg1	hydrogel					31:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	7	23	theme	chondrogenesis	1502:1515	arg1	potential					1517:1525	the chondrogenesis potential	1498:1525	the chondrogenesis potential	1498:1525	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	2	24	theme	cartilage	541:549	arg1	structure					551:559	the cartilage structure	537:559	the cartilage structure	537:559	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	25	theme	stem	362:365	arg1	hASCs					374:378	hASCs	374:378	hASCs	374:378	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	25	theme	stem	362:365	arg1	cells					367:371	human adipose-derived stem cells	340:371	human adipose-derived stem cells (hASCs)	340:379	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	1	26	theme	cartilage	204:212	arg1	engineering					221:231	cartilage tissue engineering	204:231	cartilage tissue engineering	204:231	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	0	27	theme	Alginate	0:7	arg1	hydrogel					31:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	6	28	theme	cartilage	1286:1294	arg1	structure					1296:1304	the cartilage structure	1282:1304	the cartilage structure	1282:1304	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	6	29	theme	nanofibrous	1109:1119	arg1	layers					1121:1126	electrospun nanofibrous layers	1097:1126	electrospun nanofibrous layers	1097:1126	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	2	30	theme	adipose-derived	346:360	arg1	hASCs					374:378	hASCs	374:378	hASCs	374:378	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	30	theme	adipose-derived	346:360	arg1	cells					367:371	human adipose-derived stem cells	340:371	human adipose-derived stem cells (hASCs)	340:379	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	1	31	theme	tissue	214:219	arg1	engineering					221:231	cartilage tissue engineering	204:231	cartilage tissue engineering	204:231	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	7	32	theme	biodegradation	1463:1476	arg1	behavior					1478:1485	biodegradation behavior	1463:1485	biodegradation behavior	1463:1485	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	4	33	theme	alginate	879:886	arg1	solution					896:903	an alginate sulfate solution	876:903	an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability	876:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	2	34	theme	human	340:344	arg1	hASCs					374:378	hASCs	374:378	hASCs	374:378	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	34	theme	human	340:344	arg1	cells					367:371	human adipose-derived stem cells	340:371	human adipose-derived stem cells (hASCs)	340:379	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	35	theme	electrospun	466:476	arg1	nanofibers					478:487	polycaprolactone/gelatin electrospun nanofibers	441:487	polycaprolactone/gelatin electrospun nanofibers	441:487	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	0	36	theme	composite	21:29	arg1	hydrogel					31:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel	0:38	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	5	37	theme	rheological	1029:1039	arg1	properties					1041:1050	optimal mechanical and rheological properties	1006:1050	optimal mechanical and rheological properties	1006:1050	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	7	38	theme	tissue	1597:1602	arg1	engineering					1604:1614	cartilage tissue engineering	1587:1614	cartilage tissue engineering application	1587:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	4	39	theme	1-5 	822:825	arg1	concentrations					806:819	different concentrations	796:819	different concentrations (1-5 % w/v) of ECM powder	796:845	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	4	39	theme	1-5 	822:825	arg1	 w/v					827:830	1-5 % w/v	822:830	1-5 % w/v	822:830	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	3	40	from	factors	654:660	arg1	proliferation					708:720	cell proliferation	703:720	cell proliferation	703:720	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	3	40	from	factors	654:660	arg1	differentiation					727:741	differentiation	727:741	differentiation	727:741	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	3	40	from	factors	654:660	arg1	properties					691:700	mechanical properties	680:700	mechanical properties	680:700	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	2	41	theme	polycaprolactone/gelatin	441:464	arg1	nanofibers					478:487	polycaprolactone/gelatin electrospun nanofibers	441:487	polycaprolactone/gelatin electrospun nanofibers	441:487	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	0	42	theme	electrospun	51:61	arg1	nanofiber					63:71	electrospun nanofiber	51:71	electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering	51:155	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	5	43	theme	mechanical	1014:1023	arg1	properties					1041:1050	optimal mechanical and rheological properties	1006:1050	optimal mechanical and rheological properties	1006:1050	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	6	44	theme	different	1188:1196	arg1	structures					1245:1254	different layered hydrogel-nanofiber (2, 3, and 5-layer) structures	1188:1254	different layered hydrogel-nanofiber (2, 3, and 5-layer) structures	1188:1254	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	7	45	theme	layered	1370:1376	arg1	features					1574:1581	promising features	1564:1581	promising features for cartilage tissue engineering application	1564:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	45	theme	layered	1370:1376	arg1	structure					1332:1340	The 3-layer structure	1320:1340	The 3-layer structure	1320:1340	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	45	theme	layered	1370:1376	arg1	scaffold					1388:1395	the optimum layered composite scaffold	1358:1395	the optimum layered composite scaffold	1358:1395	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	46	theme	mechanical	1426:1435	arg1	properties					1437:1446	mechanical properties	1426:1446	mechanical properties	1426:1446	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	1	47	theme	cell	238:241	arg1	transplantation					243:257	cell transplantation	238:257	cell transplantation using polymeric scaffolds	238:283	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	3	48	theme	cell	703:706	arg1	proliferation					708:720	cell proliferation	703:720	cell proliferation	703:720	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	4	49	theme	sulfate	888:894	arg1	solution					896:903	an alginate sulfate solution	876:903	an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability	876:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	0	50	link	adipose-derived	97:111	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	5	51	theme	4 	979:980	arg1	%					981:981	%	981:981	%	981:981	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	4	52	theme	hASCs	955:959	arg1	viability					961:969	encapsulated hASCs viability	942:969	encapsulated hASCs viability	942:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	7	53	theme	promising	1564:1572	arg1	features					1574:1581	promising features	1564:1581	promising features for cartilage tissue engineering application	1564:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	53	theme	promising	1564:1572	arg1	structure					1332:1340	The 3-layer structure	1320:1340	The 3-layer structure	1320:1340	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	53	theme	promising	1564:1572	arg1	scaffold					1388:1395	the optimum layered composite scaffold	1358:1395	the optimum layered composite scaffold	1358:1395	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	3	54	theme	relevant	645:652	arg1	factors					654:660	the relevant factors	641:660	the relevant factors	641:660	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	7	55	theme	3-layer	1324:1330	arg1	features					1574:1581	promising features	1564:1581	promising features for cartilage tissue engineering application	1564:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	55	theme	3-layer	1324:1330	arg1	scaffold					1388:1395	the optimum layered composite scaffold	1358:1395	the optimum layered composite scaffold	1358:1395	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	7	55	theme	3-layer	1324:1330	arg1	structure					1332:1340	The 3-layer structure	1320:1340	The 3-layer structure	1320:1340	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	5	56	theme	%	981:981	arg1	 w/v					982:985	4 % w/v	979:985	4 % w/v of ECM	979:992	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	7	57	theme	engineering	1604:1614	arg1	application					1616:1626	cartilage tissue engineering application	1587:1626	cartilage tissue engineering application	1587:1626	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	2	58	link	adipose-derived	346:360	arg1	hASCs					374:378	hASCs	374:378	hASCs	374:378	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	2	58	link	adipose-derived	346:360	arg1	cells					367:371	human adipose-derived stem cells	340:371	human adipose-derived stem cells (hASCs)	340:379	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	7	59	theme	cell	1410:1413	arg1	viability					1415:1423	cell viability	1410:1423	cell viability	1410:1423	The 3-layer structure was selected as the optimum layered composite scaffold, considering cell viability, mechanical properties, swelling, and biodegradation behavior; moreover, the chondrogenesis potential was assessed, and the results showed promising features for cartilage tissue engineering application.					
36948341	3	60	theme	mechanical	680:689	arg1	properties					691:700	mechanical properties	680:700	mechanical properties	680:700	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	1	61	theme	Stem	158:161	arg1	strategy					191:198	a promising strategy	179:198	a promising strategy for cartilage tissue engineering	179:231	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	1	61	theme	Stem	158:161	arg1	therapy					168:174	Stem cell therapy	158:174	Stem cell therapy	158:174	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	4	62	theme	%	826:826	arg1	concentrations					806:819	different concentrations	796:819	different concentrations (1-5 % w/v) of ECM powder	796:845	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	4	62	theme	%	826:826	arg1	 w/v					827:830	1-5 % w/v	822:830	1-5 % w/v	822:830	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	6	63	theme	next	1086:1089	arg1	step					1091:1094	the next step	1082:1094	the next step	1082:1094	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	3	64	theme	composite	585:593	arg1	scaffolds					604:612	The composite hydrogel scaffolds	581:612	The composite hydrogel scaffolds	581:612	The composite hydrogel scaffolds were developed to evaluate the relevant factors and conditions in mechanical properties, cell proliferation, and differentiation to enhance cartilage regeneration.					
36948341	4	65	theme	powder	840:845	arg1	concentrations					806:819	different concentrations	796:819	different concentrations (1-5 % w/v) of ECM powder	796:845	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	4	65	theme	powder	840:845	arg1	 w/v					827:830	1-5 % w/v	822:830	1-5 % w/v	822:830	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	1	66	theme	cell	163:166	arg1	strategy					191:198	a promising strategy	179:198	a promising strategy for cartilage tissue engineering	179:231	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	1	66	theme	cell	163:166	arg1	therapy					168:174	Stem cell therapy	158:174	Stem cell therapy	158:174	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	4	67	theme	different	796:804	arg1	concentrations					806:819	different concentrations	796:819	different concentrations (1-5 % w/v) of ECM powder	796:845	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	4	67	theme	different	796:804	arg1	 w/v					827:830	1-5 % w/v	822:830	1-5 % w/v	822:830	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	0	68	theme	human	91:95	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	6	69	theme	sulfate/ECM	1155:1165	arg1	composite					1167:1175	the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function	1142:1317	the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function	1142:1317	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	5	70	theme	cell	1063:1066	arg1	viability					1068:1076	better cell viability	1056:1076	better cell viability	1056:1076	Adding 4 % w/v of ECM resulted in optimal mechanical and rheological properties and better cell viability.					
36948341	0	71	with	nanofiber	63:71	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	2	72	theme	sulfate	401:407	arg1	hydrogel					409:416	the alginate sulfate hydrogel	388:416	the alginate sulfate hydrogel	388:416	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
36948341	1	73	theme	polymeric	265:273	arg1	scaffolds					275:283	polymeric scaffolds	265:283	polymeric scaffolds	265:283	Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell transplantation using polymeric scaffolds has recently gained attention.					
36948341	0	74	theme	encapsulated	78:89	arg1	cells					118:122	encapsulated human adipose-derived stem cells	78:122	encapsulated human adipose-derived stem cells	78:122	Alginate sulfate/ECM composite hydrogel containing electrospun nanofiber with encapsulated human adipose-derived stem cells for cartilage tissue engineering.					
36948341	6	75	theme	hydrogel-nanofiber	1206:1223	arg1	structures					1245:1254	different layered hydrogel-nanofiber (2, 3, and 5-layer) structures	1188:1254	different layered hydrogel-nanofiber (2, 3, and 5-layer) structures	1188:1254	In the next step, electrospun nanofibrous layers were added to the alginate sulfate/ECM composite to prepare different layered hydrogel-nanofiber (2, 3, and 5-layer) structures with the ability to mimic the cartilage structure and function.					
36948341	4	76	dep	solution	896:903	arg1	optimize					908:915	optimize	908:915	to optimize the best composition for encapsulated hASCs viability	905:969	For this purpose, different concentrations (1-5 % w/v) of ECM powder were initially loaded within an alginate sulfate solution to optimize the best composition for encapsulated hASCs viability.					
36948341	2	77	theme	alginate	392:399	arg1	hydrogel					409:416	the alginate sulfate hydrogel	388:416	the alginate sulfate hydrogel	388:416	Herein, we encapsulated human adipose-derived stem cells (hASCs) within the alginate sulfate hydrogel and then added them to polycaprolactone/gelatin electrospun nanofibers and extracellular matrix (ECM) powders to mimic the cartilage structure and characteristic.					
35682630	7	0	theme	cell	1291:1294	arg1	response					1296:1303	proper cell response	1284:1303	proper cell response	1284:1303	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	0	theme	cell	1291:1294	arg1	properties					1251:1260	These unique properties	1238:1260	These unique properties	1238:1260	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	6	1	theme	chemical	1019:1026	arg1	interactions					1028:1039	Strong chemical interactions	1012:1039	Strong chemical interactions	1012:1039	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	1	2	theme	surface	172:178	arg1	characteristics					180:194	surface characteristics	172:194	surface characteristics	172:194	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	4	3	theme	microscopic	655:665	arg1	approaches					667:676	various spectroscopic and microscopic approaches	629:676	various spectroscopic and microscopic approaches	629:676	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	3	theme	microscopic	655:665	arg1	such					679:682	such	679:682	such	679:682	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	4	theme	Raman	768:772	arg1	spectroscopy					774:785	Raman spectroscopy	768:785	Raman spectroscopy	768:785	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	5	5	theme	groups	939:944	arg1	involvement					901:911	the involvement	897:911	the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization	897:1009	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	4	6	theme	force	838:842	arg1	AFM					856:858	AFM	856:858	AFM	856:858	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	6	theme	force	838:842	arg1	microscopy					844:853	atomic force microscopy	831:853	atomic force microscopy (AFM)	831:859	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	6	7	theme	sample	1210:1215	arg1	surface					1195:1201	the uniform surface	1183:1201	the uniform surface of the sample without segregation	1183:1235	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	7	8	theme	studied	1344:1350	arg1	biomaterial					1352:1362	studied biomaterial	1344:1362	studied biomaterial	1344:1362	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	4	9	theme	atomic	831:836	arg1	AFM					856:858	AFM	856:858	AFM	856:858	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	9	theme	atomic	831:836	arg1	microscopy					844:853	atomic force microscopy	831:853	atomic force microscopy (AFM)	831:859	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	7	10	theme	potential	1319:1327	arg1	application					1329:1339	the potential application	1315:1339	the potential application of studied biomaterial	1315:1362	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	10	theme	potential	1319:1327	arg1	scaffolds					1381:1389	biocompatible scaffolds	1367:1389	biocompatible scaffolds used in regenerative medicine	1367:1419	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	2	11	theme	research	315:322	arg1	aim					303:305	The aim	299:305	The aim of this research	299:322	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	4	12	theme	photoelectron	794:806	arg1	XPS					822:824	XPS	822:824	XPS	822:824	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	12	theme	photoelectron	794:806	arg1	spectroscopy					808:819	X-ray photoelectron spectroscopy	788:819	X-ray photoelectron spectroscopy (XPS)	788:825	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	7	13	theme	hybrid	1263:1268	arg1	properties					1251:1260	These unique properties	1238:1260	These unique properties	1238:1260	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	13	theme	hybrid	1263:1268	arg1	character					1270:1278	hybrid character	1263:1278	hybrid character	1263:1278	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	5	14	theme	moieties	957:964	arg1	involvement					901:911	the involvement	897:911	the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization	897:1009	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	7	15	theme	unique	1244:1249	arg1	response					1296:1303	proper cell response	1284:1303	proper cell response	1284:1303	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	15	theme	unique	1244:1249	arg1	properties					1251:1260	These unique properties	1238:1260	These unique properties	1238:1260	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	15	theme	unique	1244:1249	arg1	character					1270:1278	hybrid character	1263:1278	hybrid character	1263:1278	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	16	theme	regenerative	1399:1410	arg1	medicine					1412:1419	regenerative medicine	1399:1419	regenerative medicine	1399:1419	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	5	17	theme	C-C	927:929	arg1	groups					939:944	the C-C and C-H groups	923:944	groups	939:944	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	6	18	theme	ionocovalent	1045:1056	arg1	bonds					1058:1062	ionocovalent bonds	1045:1062	ionocovalent bonds	1045:1062	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	5	19	theme	C=O⋯HN	950:955	arg1	moieties					957:964	C=O⋯HN moieties	950:964	C=O⋯HN moieties	950:964	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	2	20	theme	matrices	439:446	arg1	interlinkage					385:396	unit interlinkage	380:396	unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C	380:462	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	0	21	theme	Chemical	8:15	arg1	Analysis					35:42	Surface Chemical and Morphological Analysis	0:42	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films	0:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	6	22	theme	Strong	1012:1017	arg1	interactions					1028:1039	Strong chemical interactions	1012:1039	Strong chemical interactions	1012:1039	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	7	23	theme	biomaterial	1352:1362	arg1	application					1329:1339	the potential application	1315:1339	the potential application of studied biomaterial	1315:1362	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	23	theme	biomaterial	1352:1362	arg1	scaffolds					1381:1389	biocompatible scaffolds	1367:1389	biocompatible scaffolds used in regenerative medicine	1367:1419	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	2	24	theme	chitosan/1,3-β-d-glucan	415:437	arg1	matrices					439:446	two-component chitosan/1,3-β-d-glucan matrices	401:446	two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C	401:462	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	0	25	theme	Surface	0:6	arg1	Analysis					35:42	Surface Chemical and Morphological Analysis	0:42	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films	0:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	1	26	dep	characteristics	180:194	arg1	the					168:170	the	168:170	the	168:170	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	2	27	theme	two-component	401:413	arg1	matrices					439:446	two-component chitosan/1,3-β-d-glucan matrices	401:446	two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C	401:462	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	0	28	theme	Morphological	21:33	arg1	Analysis					35:42	Surface Chemical and Morphological Analysis	0:42	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films	0:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	5	29	theme	polymerization	996:1009	arg1	process					973:979	the process	969:979	the process of biomaterial polymerization	969:1009	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	5	30	theme	biomaterial	984:994	arg1	polymerization					996:1009	biomaterial polymerization	984:1009	biomaterial polymerization	984:1009	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	4	31	theme	spectroscopic	637:649	arg1	approaches					667:676	various spectroscopic and microscopic approaches	629:676	various spectroscopic and microscopic approaches	629:676	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	31	theme	spectroscopic	637:649	arg1	such					679:682	such	679:682	such	679:682	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	1	32	theme	cross-linking	119:131	arg1	temperature					133:143	The cross-linking temperature	115:143	The cross-linking temperature of polymers	115:155	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	4	33	theme	reflection	704:713	arg1	Fourier					715:721	attenuated total reflection Fourier	687:721	attenuated total reflection Fourier	687:721	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	34	theme	various	629:635	arg1	approaches					667:676	various spectroscopic and microscopic approaches	629:676	various spectroscopic and microscopic approaches	629:676	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	34	theme	various	629:635	arg1	such					679:682	such	679:682	such	679:682	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	6	35	theme	1,3-β-d-glucan	1115:1128	arg1	moieties					1090:1097	the N-glucosamine moieties	1072:1097	the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units	1072:1134	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	4	36	theme	ATR	756:758	arg1	spectroscopy					742:753	infrared spectroscopy	733:753	infrared spectroscopy (ATR FT-IR)	733:765	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	36	theme	ATR	756:758	arg1	FT-IR					760:764	ATR FT-IR	756:764	ATR FT-IR	756:764	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	37	theme	infrared	733:740	arg1	spectroscopy					742:753	infrared spectroscopy	733:753	infrared spectroscopy (ATR FT-IR)	733:765	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	37	theme	infrared	733:740	arg1	FT-IR					760:764	ATR FT-IR	756:764	ATR FT-IR	756:764	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	2	38	theme	unit	380:383	arg1	interlinkage					385:396	unit interlinkage	380:396	unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C	380:462	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	6	39	theme	N-glucosamine	1076:1088	arg1	moieties					1090:1097	the N-glucosamine moieties	1072:1097	the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units	1072:1134	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	5	40	from	involvement	901:911	arg1	process					973:979	the process	969:979	the process of biomaterial polymerization	969:1009	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	0	41	theme	Polysaccharide	71:84	arg1	Films					86:90	Chitosan/1,3-β-d-Glucan Polysaccharide Films	47:90	Chitosan/1,3-β-d-Glucan Polysaccharide Films	47:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	5	42	theme	C-H	935:937	arg1	groups					939:944	the C-C and C-H groups	923:944	groups	939:944	The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization.					
35682630	6	43	dep	chitosan	1102:1109	arg1	units					1130:1134	units	1130:1134	units	1130:1134	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	4	44	theme	X-ray	788:792	arg1	XPS					822:824	XPS	822:824	XPS	822:824	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	4	44	theme	X-ray	788:792	arg1	spectroscopy					808:819	X-ray photoelectron spectroscopy	788:819	X-ray photoelectron spectroscopy (XPS)	788:825	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	0	45	theme	Chitosan/1,3-β-d-Glucan	47:69	arg1	Films					86:90	Chitosan/1,3-β-d-Glucan Polysaccharide Films	47:90	Chitosan/1,3-β-d-Glucan Polysaccharide Films	47:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	7	46	theme	proper	1284:1289	arg1	response					1296:1303	proper cell response	1284:1303	proper cell response	1284:1303	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	46	theme	proper	1284:1289	arg1	properties					1251:1260	These unique properties	1238:1260	These unique properties	1238:1260	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	3	47	theme	surface	551:557	arg1	topography					559:568	surface topography	551:568	surface topography providing material chemical composition	551:608	This required identifying functional groups interacting with each other and assessing surface topography providing material chemical composition.					
35682630	1	48	theme	polymers	148:155	arg1	temperature					133:143	The cross-linking temperature	115:143	The cross-linking temperature of polymers	115:155	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	6	49	theme	uniform	1187:1193	arg1	surface					1195:1201	the uniform surface	1183:1201	the uniform surface of the sample without segregation	1183:1235	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	6	50	theme	chitosan	1102:1109	arg1	moieties					1090:1097	the N-glucosamine moieties	1072:1097	the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units	1072:1134	Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation.					
35682630	7	51	theme	biocompatible	1367:1379	arg1	application					1329:1339	the potential application	1315:1339	the potential application of studied biomaterial	1315:1362	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	51	theme	biocompatible	1367:1379	arg1	scaffolds					1381:1389	biocompatible scaffolds	1367:1389	biocompatible scaffolds used in regenerative medicine	1367:1419	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	7	52	theme	wound	1460:1464	arg1	healing					1466:1472	wound healing	1460:1472	wound healing	1460:1472	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	2	53	theme	interlinkage	385:396	arg1	mechanism					367:375	the mechanism	363:375	the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C	363:462	The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C.					
35682630	1	54	theme	mechanical	255:264	arg1	properties					287:296	their mechanical and physico-chemical properties	249:296	their mechanical and physico-chemical properties	249:296	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	3	55	theme	functional	491:500	arg1	groups					502:507	functional groups	491:507	functional groups interacting with each other	491:535	This required identifying functional groups interacting with each other and assessing surface topography providing material chemical composition.					
35682630	4	56	dep	such	679:682	arg1	transform					723:731	transform	723:731	transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM)	723:859	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	7	57	theme	bone	1436:1439	arg1	restoration					1441:1451	bone restoration	1436:1451	bone restoration	1436:1451	These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.					
35682630	3	58	theme	material	580:587	arg1	composition					598:608	material chemical composition	580:608	material chemical composition	580:608	This required identifying functional groups interacting with each other and assessing surface topography providing material chemical composition.					
35682630	1	59	theme	molecular	200:208	arg1	arrangement					210:220	molecular arrangement	200:220	molecular arrangement	200:220	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35682630	4	60	theme	total	698:702	arg1	Fourier					715:721	attenuated total reflection Fourier	687:721	attenuated total reflection Fourier	687:721	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	0	61	theme	Films	86:90	arg1	Analysis					35:42	Surface Chemical and Morphological Analysis	0:42	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films	0:90	Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.					
35682630	4	62	theme	attenuated	687:696	arg1	Fourier					715:721	attenuated total reflection Fourier	687:721	attenuated total reflection Fourier	687:721	For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied.					
35682630	3	63	theme	chemical	589:596	arg1	composition					598:608	material chemical composition	580:608	material chemical composition	580:608	This required identifying functional groups interacting with each other and assessing surface topography providing material chemical composition.					
35682630	1	64	theme	physico-chemical	270:285	arg1	properties					287:296	their mechanical and physico-chemical properties	249:296	their mechanical and physico-chemical properties	249:296	The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties.					
35315273	0	0	theme	Cellulose	82:90	arg1	Nanocrystals					92:103	Cellulose Nanocrystals	82:103	Cellulose Nanocrystals	82:103	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	6	1	theme	preparation	940:950	arg1	simplicity					917:926	The simplicity	913:926	The simplicity of the film preparation	913:950	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	1	theme	preparation	940:950	arg1	stability					1000:1008	stability	1000:1008	stability	1000:1008	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	1	theme	preparation	940:950	arg1	abundance					957:965	the abundance	953:965	the abundance of CNCs	953:973	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	1	theme	preparation	940:950	arg1	flexibility					984:994	flexibility	984:994	flexibility	984:994	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	3	2	theme	chiral	499:504	arg1	structure					514:522	the chiral nematic structure	495:522	the chiral nematic structure	495:522	It was found that the composite film retained the chiral nematic structure and optical activity.					
35315273	6	3	with	materials	1079:1087	arg1	functions					1105:1113	integrated functions	1094:1113	integrated functions	1094:1113	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	5	4	theme	third	726:730	arg1	Meanwhile					711:719	Meanwhile	711:719	Meanwhile	711:719	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	5	4	theme	third	726:730	arg1	component					732:740	the third component	722:740	the third component	722:740	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	6	5	theme	film	935:938	arg1	preparation					940:950	the film preparation	931:950	the film preparation	931:950	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	2	6	theme	concentration	344:356	arg1	influences					317:326	The influences	313:326	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films	313:425	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	4	7	theme	helical	582:588	arg1	superstructures					590:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	5	8	theme	polyethylene	743:754	arg1	Meanwhile					711:719	Meanwhile	711:719	Meanwhile	711:719	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	5	8	theme	polyethylene	743:754	arg1	glycol					756:761	polyethylene glycol	743:761	polyethylene glycol	743:761	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	2	9	from	influences	317:326	arg1	properties					387:396	optical properties	379:396	optical properties	379:396	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	2	9	from	influences	317:326	arg1	structure					365:373	structure	365:373	structure	365:373	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	1	10	theme	bovine	250:255	arg1	nanoclusters					287:298	bovine serum albumin-stabilized gold nanoclusters	250:298	bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs)	250:310	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	10	theme	bovine	250:255	arg1	BSA-AuNCs					301:309	BSA-AuNCs	301:309	BSA-AuNCs	301:309	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	0	11	theme	Nanocrystals	92:103	arg1	Coassembly					68:77	the Coassembly	64:77	the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters	64:125	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	1	12	theme	serum	257:261	arg1	nanoclusters					287:298	bovine serum albumin-stabilized gold nanoclusters	250:298	bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs)	250:310	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	12	theme	serum	257:261	arg1	BSA-AuNCs					301:309	BSA-AuNCs	301:309	BSA-AuNCs	301:309	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	0	13	theme	Nanoclusters	114:125	arg1	Coassembly					68:77	the Coassembly	64:77	the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters	64:125	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	2	14	theme	films	421:425	arg1	properties					387:396	optical properties	379:396	optical properties	379:396	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	2	14	theme	films	421:425	arg1	structure					365:373	structure	365:373	structure	365:373	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	2	15	dep	structure	365:373	arg1	the					361:363	the	361:363	the	361:363	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	6	16	theme	functional	1068:1077	arg1	materials					1079:1087	functional materials	1068:1087	functional materials with integrated functions	1068:1113	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	0	17	theme	Gold	109:112	arg1	Nanoclusters					114:125	Gold Nanoclusters	109:125	Gold Nanoclusters	109:125	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	4	18	dep	0.287	704:708	arg1	up					698:699	up	698:699	up	698:699	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	6	19	theme	integrated	1094:1103	arg1	functions					1105:1113	integrated functions	1094:1113	integrated functions	1094:1113	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	4	20	theme	dissymmetry	678:688	arg1	factors					690:696	dissymmetry factors	678:696	dissymmetry factors up to 0.287	678:708	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	0	21	theme	Polarized	11:19	arg1	Films					49:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	4	22	theme	CNC	565:567	arg1	superstructures					590:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	2	23	theme	optical	379:385	arg1	properties					387:396	optical properties	379:396	optical properties	379:396	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	1	24	theme	albumin-stabilized	263:280	arg1	nanoclusters					287:298	bovine serum albumin-stabilized gold nanoclusters	250:298	bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs)	250:310	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	24	theme	albumin-stabilized	263:280	arg1	BSA-AuNCs					301:309	BSA-AuNCs	301:309	BSA-AuNCs	301:309	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	5	25	theme	film	907:910	arg1	flexibility					888:898	the flexibility	884:898	the flexibility of the film	884:910	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	0	26	theme	Chiral	33:38	arg1	Films					49:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	1	27	theme	gold	282:285	arg1	nanoclusters					287:298	bovine serum albumin-stabilized gold nanoclusters	250:298	bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs)	250:310	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	27	theme	gold	282:285	arg1	BSA-AuNCs					301:309	BSA-AuNCs	301:309	BSA-AuNCs	301:309	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	28	theme	composite	185:193	arg1	films					195:199	composite films	185:199	composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs)	185:310	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	0	29	theme	Luminescent	21:31	arg1	Films					49:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	4	30	theme	BSA-AuNC	573:580	arg1	superstructures					590:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	3	31	theme	optical	528:534	arg1	activity					536:543	optical activity	528:543	optical activity	528:543	It was found that the composite film retained the chiral nematic structure and optical activity.					
35315273	3	32	theme	nematic	506:512	arg1	structure					514:522	the chiral nematic structure	495:522	the chiral nematic structure	495:522	It was found that the composite film retained the chiral nematic structure and optical activity.					
35315273	1	33	theme	films	195:199	arg1	properties					171:180	properties	171:180	properties	171:180	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	33	theme	films	195:199	arg1	formation					157:165	formation	157:165	formation	157:165	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	5	34	theme	structural	801:810	arg1	color					812:816	the structural color and fluorescence characteristics	797:849	color	812:816	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	2	35	theme	composite	411:419	arg1	films					421:425	CNC-based composite films	401:425	CNC-based composite films	401:425	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	0	36	theme	Photonic	40:47	arg1	Films					49:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films	0:53	Circularly Polarized Luminescent Chiral Photonic Films Based on the Coassembly of Cellulose Nanocrystals and Gold Nanoclusters.					
35315273	6	37	theme	CNCs	970:973	arg1	simplicity					917:926	The simplicity	913:926	The simplicity of the film preparation	913:950	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	37	theme	CNCs	970:973	arg1	stability					1000:1008	stability	1000:1008	stability	1000:1008	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	37	theme	CNCs	970:973	arg1	abundance					957:965	the abundance	953:965	the abundance of CNCs	953:973	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	37	theme	CNCs	970:973	arg1	flexibility					984:994	flexibility	984:994	flexibility	984:994	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	2	38	theme	CNC-based	401:409	arg1	films					421:425	CNC-based composite films	401:425	CNC-based composite films	401:425	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	4	39	theme	self-assembled	550:563	arg1	superstructures					590:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures	546:604	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	1	40	dep	formation	157:165	arg1	the					153:155	the	153:155	the	153:155	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	2	41	theme	BSA-AuNC	335:342	arg1	concentration					344:356	the BSA-AuNC concentration	331:356	the BSA-AuNC concentration	331:356	The influences of the BSA-AuNC concentration on the structure and optical properties of CNC-based composite films were further studied.					
35315273	5	42	theme	fluorescence	822:833	arg1	characteristics					835:849	the structural color and fluorescence characteristics	797:849	characteristics	835:849	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	4	43	with	luminescence	660:671	arg1	factors					690:696	dissymmetry factors	678:696	dissymmetry factors up to 0.287	678:708	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	3	44	theme	composite	471:479	arg1	film					481:484	the composite film	467:484	the composite film	467:484	It was found that the composite film retained the chiral nematic structure and optical activity.					
35315273	1	45	theme	cellulose	216:224	arg1	CNCs					240:243	CNCs	240:243	CNCs	240:243	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	1	45	theme	cellulose	216:224	arg1	nanocrystals					226:237	cellulose nanocrystals	216:237	cellulose nanocrystals (CNCs)	216:244	In this work, we studied the formation and properties of composite films coassembled by cellulose nanocrystals (CNCs) and bovine serum albumin-stabilized gold nanoclusters (BSA-AuNCs).					
35315273	4	46	theme	strong	618:623	arg1	luminescence					660:671	strong, left-handed, circularly polarized luminescence	618:671	strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287	618:708	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	4	47	dep	strong	618:623	arg1	left-handed					626:636	left-handed	626:636	left-handed	626:636	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	4	47	dep	strong	618:623	arg1	polarized					650:658	polarized	650:658	polarized	650:658	The self-assembled CNC and BSA-AuNC helical superstructures can produce strong, left-handed, circularly polarized luminescence with dissymmetry factors up to 0.287.					
35315273	5	48	theme	film	868:871	arg1	color					812:816	the structural color and fluorescence characteristics	797:849	color	812:816	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	5	48	theme	film	868:871	arg1	characteristics					835:849	the structural color and fluorescence characteristics	797:849	characteristics	835:849	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	6	49	theme	materials	1079:1087	arg1	production					1054:1063	the production	1050:1063	the production of functional materials with integrated functions	1050:1113	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	50	theme	films	1027:1031	arg1	simplicity					917:926	The simplicity	913:926	The simplicity of the film preparation	913:950	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	50	theme	films	1027:1031	arg1	stability					1000:1008	stability	1000:1008	stability	1000:1008	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	50	theme	films	1027:1031	arg1	abundance					957:965	the abundance	953:965	the abundance of CNCs	953:973	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	6	50	theme	films	1027:1031	arg1	flexibility					984:994	flexibility	984:994	flexibility	984:994	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
35315273	5	51	theme	composite	858:866	arg1	film					868:871	the composite film	854:871	the composite film to enhance the flexibility of the film	854:910	Meanwhile, the third component, polyethylene glycol, was introduced without affecting the structural color and fluorescence characteristics of the composite film to enhance the flexibility of the film.					
35315273	6	52	theme	composite	1017:1025	arg1	films					1027:1031	the composite films	1013:1031	the composite films	1013:1031	The simplicity of the film preparation, the abundance of CNCs, and the flexibility and stability of the composite films pave the way for the production of functional materials with integrated functions.					
37068536	10	0	theme	index	1679:1683	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	0	theme	index	1679:1683	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	0	theme	index	1679:1683	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	0	theme	index	1679:1683	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	0	theme	index	1679:1683	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	1	theme	nanocellulose	1767:1779	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	1	theme	nanocellulose	1767:1779	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	1	theme	nanocellulose	1767:1779	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	1	theme	nanocellulose	1767:1779	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	1	theme	nanocellulose	1767:1779	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	4	2	link	GA-crosslinked	848:861	arg1	scaffolds					903:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	7	3	from	area	1205:1208	arg1	turn					1213:1216	turn	1213:1216	turn	1213:1216	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	6	4	theme	surface	1102:1108	arg1	area					1110:1113	the surface area	1098:1113	the surface area of the GA crosslinked nano-cellulose scaffold	1098:1159	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	10	5	theme	good	1697:1700	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	5	theme	good	1697:1700	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	5	theme	good	1697:1700	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	5	theme	good	1697:1700	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	5	theme	good	1697:1700	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	3	6	theme	techniques	553:562	arg1	Fourier					575:581	Fourier	575:581	Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis	575:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	6	theme	techniques	553:562	arg1	variety					525:531	a variety	523:531	a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis	523:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	6	theme	techniques	553:562	arg1	techniques					553:562	characterization techniques	536:562	characterization techniques	536:562	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	6	7	theme	study	1080:1084	arg1	results					1061:1067	The results	1057:1067	The results of the BET study	1057:1084	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	10	8	dep	nanocellulose	1767:1779	arg1	encourages					1781:1790	encourages	1781:1790	encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1781:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	4	9	dep	higher	916:921	arg1	88.82 MPa					924:932	88.82 MPa	924:932	88.82 MPa	924:932	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	10	10	theme	other	1727:1731	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	10	theme	other	1727:1731	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	10	theme	other	1727:1731	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	10	theme	other	1727:1731	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	10	theme	other	1727:1731	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	1	11	theme	plentiful	173:181	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	4	12	theme	nanocellulose	889:901	arg1	scaffolds					903:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	10	13	dep	its	1792:1794	arg1	uses					1796:1799	uses	1796:1799	uses	1796:1799	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	3	14	theme	BET	732:734	arg1	analysis					737:744	Brunauer-Emmett-Teller (BET) analysis	708:744	Brunauer-Emmett-Teller (BET) analysis	708:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	1	15	theme	resources	191:199	arg1	subset					104:109	a subset	102:109	a subset of nanomaterials made from cellulose	102:146	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	15	theme	resources	191:199	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	15	theme	resources	191:199	arg1	one					149:151	one	149:151	one	149:151	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	10	16	theme	insulation	1873:1882	arg1	coatings					1884:1891	insulation coatings	1873:1891	insulation coatings	1873:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	3	17	theme	Brunauer-Emmett-Teller	708:729	arg1	analysis					737:744	Brunauer-Emmett-Teller (BET) analysis	708:744	Brunauer-Emmett-Teller (BET) analysis	708:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	10	18	theme	GA-treated	1756:1765	arg1	nanocellulose					1767:1779	the GA-treated nanocellulose	1752:1779	the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1752:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	9	19	theme	blue	1429:1432	arg1	dye					1434:1436	textile black dye and methylene blue dye	1397:1436	dye	1434:1436	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	6	20	theme	nano-cellulose	1137:1150	arg1	scaffold					1152:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	5	21	theme	scaffold	1000:1007	arg1	modulus					1017:1023	The scaffold Young's modulus	996:1023	The scaffold Young's modulus	996:1023	The scaffold Young's modulus has been increased to 86.3 MPa.					
37068536	10	22	theme	product	1804:1810	arg1	packaging					1812:1820	product packaging	1804:1820	product packaging	1804:1820	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	2	23	attach	derived	477:483	arg1	root					511:514	I. coccinea L. plant root	490:514	I. coccinea L. plant root	490:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	2	23	attach	derived	477:483	arg2	nanocellulose					463:475	glycerol plasticized nanocellulose	442:475	glycerol plasticized nanocellulose derived from I. coccinea L. plant root	442:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	3	24	theme	plasticized	776:786	arg1	nano-cellulose					788:801	glycerol plasticized nano-cellulose	767:801	glycerol plasticized nano-cellulose	767:801	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	9	25	theme	dye	1434:1436	arg1	absorbance					1383:1392	The absorbance	1379:1392	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst	1379:1496	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	4	26	dep	GA-crosslinked	848:861	arg1	glycerol-plasticized					868:887	glycerol-plasticized	868:887	glycerol-plasticized	868:887	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	1	27	theme	enhanced	303:310	arg1	properties					312:321	enhanced properties	303:321	enhanced properties	303:321	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	2	28	from	impact	409:414	arg1	nanocellulose					463:475	glycerol plasticized nanocellulose	442:475	glycerol plasticized nanocellulose derived from I. coccinea L. plant root	442:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	0	29	theme	bio-adsorbent	59:71	arg1	applications					73:84	bio-adsorbent applications	59:84	bio-adsorbent applications	59:84	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	2	30	theme	plant	505:509	arg1	root					511:514	I. coccinea L. plant root	490:514	I. coccinea L. plant root	490:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	2	31	theme	coccinea	493:500	arg1	root					511:514	I. coccinea L. plant root	490:514	I. coccinea L. plant root	490:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	1	32	theme	applications	340:351	arg1	applications					340:351	applications	340:351	applications in the nanotechnology field	340:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	32	theme	applications	340:351	arg1	variety					329:335	a variety	327:335	a variety of applications in the nanotechnology field	327:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	7	33	theme	consecutive	1271:1281	arg1	fibers					1283:1288	consecutive fibers	1271:1288	consecutive fibers	1271:1288	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	0	34	theme	Ixora	0:4	arg1	L.					15:16	Ixora coccinea L.	0:16	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.	0:85	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	7	35	theme	sites	1257:1261	arg1	number					1239:1244	a greater number	1229:1244	a greater number of contact sites between consecutive fibers	1229:1288	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	9	36	theme	dye	1533:1535	arg1	concentration					1537:1549	dye concentration	1533:1549	dye concentration	1533:1549	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	2	37	theme	glycerol	442:449	arg1	nanocellulose					463:475	glycerol plasticized nanocellulose	442:475	glycerol plasticized nanocellulose derived from I. coccinea L. plant root	442:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	3	38	theme	Powder	629:634	arg1	XRD					649:651	XRD	649:651	XRD	649:651	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	38	theme	Powder	629:634	arg1	Diffraction					636:646	X-ray Powder Diffraction	623:646	X-ray Powder Diffraction (XRD)	623:652	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	10	39	theme	non-toxic	1626:1634	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	39	theme	non-toxic	1626:1634	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	39	theme	non-toxic	1626:1634	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	39	theme	non-toxic	1626:1634	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	39	theme	non-toxic	1626:1634	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	1	40	theme	sustainable	270:280	arg1	blocks					291:296	sustainable building blocks	270:296	sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field	270:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	7	41	theme	greater	1231:1237	arg1	number					1239:1244	a greater number	1229:1244	a greater number of contact sites between consecutive fibers	1229:1288	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	4	42	theme	nanocellulose	960:972	arg1	78.8 MPa					985:992	78.8 MPa	985:992	78.8 MPa	985:992	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	4	42	theme	nanocellulose	960:972	arg1	scaffolds					974:982	the regular nanocellulose scaffolds	948:982	the regular nanocellulose scaffolds (78.8 MPa)	948:993	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	0	43	theme	nanocellulose	41:53	arg1	source					31:36	A reliable source	20:36	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.	0:85	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	10	44	theme	crystallinity	1665:1677	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	44	theme	crystallinity	1665:1677	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	44	theme	crystallinity	1665:1677	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	44	theme	crystallinity	1665:1677	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	44	theme	crystallinity	1665:1677	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	8	45	theme	waste	1356:1360	arg1	treatment					1368:1376	waste water treatment	1356:1376	waste water treatment	1356:1376	This enhances the utility of the scaffold as a bio-adsorbent for waste water treatment.					
37068536	0	46	dep	L.	15:16	arg1	source					31:36	A reliable source	20:36	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.	0:85	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	9	47	from	absorbance	1383:1392	arg1	sunlight					1441:1448	sunlight	1441:1448	sunlight using nanocellulose composites as photocatalyst	1441:1496	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	10	48	theme	tissue	1849:1854	arg1	engineering					1856:1866	tissue engineering	1849:1866	tissue engineering	1849:1866	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	9	49	theme	bio-adsorbent	1598:1610	arg1	property					1612:1619	the composites' bio-adsorbent property	1582:1619	the composites' bio-adsorbent property	1582:1619	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	1	50	with	blocks	291:296	arg1	properties					312:321	enhanced properties	303:321	enhanced properties	303:321	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	7	51	theme	larger	1190:1195	arg1	area					1205:1208	The larger surface area	1186:1208	The larger surface area in turn	1186:1216	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	3	52	theme	Scanning	655:662	arg1	SEM					685:687	SEM	685:687	SEM	685:687	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	52	theme	Scanning	655:662	arg1	Microscopy					673:682	Scanning Electron Microscopy	655:682	Scanning Electron Microscopy (SEM)	655:688	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	4	53	theme	tensile	825:831	arg1	higher					916:921	higher	916:921	higher	916:921	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	4	53	theme	tensile	825:831	arg1	modulus					833:839	The tensile modulus	821:839	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	821:911	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	10	54	theme	mechanical	1702:1711	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	54	theme	mechanical	1702:1711	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	54	theme	mechanical	1702:1711	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	54	theme	mechanical	1702:1711	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	54	theme	mechanical	1702:1711	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	1	55	theme	world	160:164	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	3	56	theme	characterization	536:551	arg1	Fourier					575:581	Fourier	575:581	Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis	575:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	56	theme	characterization	536:551	arg1	techniques					553:562	characterization techniques	536:562	characterization techniques	536:562	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	57	dep	Fourier	575:581	arg1	Transform					583:591	Transform	583:591	Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis	583:744	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	1	58	theme	most	168:171	arg1	world					160:164	the world's most	156:171	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	6	59	theme	BET	1076:1078	arg1	study					1080:1084	the BET study	1072:1084	the BET study	1072:1084	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	1	60	theme	nanotechnology	360:373	arg1	field					375:379	the nanotechnology field	356:379	the nanotechnology field	356:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	9	61	theme	dye	1411:1413	arg1	absorbance					1383:1392	The absorbance	1379:1392	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst	1379:1496	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	1	62	contain	has	202:204	arg1	subset					104:109	a subset	102:109	a subset of nanomaterials made from cellulose	102:146	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	62	contain	has	202:204	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	62	contain	has	202:204	arg2	potential					210:218	the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field	206:379	the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field	206:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	62	contain	has	202:204	arg1	one					149:151	one	149:151	one	149:151	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	9	63	theme	methylene	1419:1427	arg1	dye					1434:1436	textile black dye and methylene blue dye	1397:1436	dye	1434:1436	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	6	64	theme	scaffold	1152:1159	arg1	area					1110:1113	the surface area	1098:1113	the surface area of the GA crosslinked nano-cellulose scaffold	1098:1159	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	6	65	link	crosslinked	1125:1135	arg1	scaffold					1152:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	1	66	theme	nanomaterials	114:126	arg1	subset					104:109	a subset	102:109	a subset of nanomaterials made from cellulose	102:146	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	66	theme	nanomaterials	114:126	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	66	theme	nanomaterials	114:126	arg1	one					149:151	one	149:151	one	149:151	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	4	67	theme	GA-crosslinked	848:861	arg1	scaffolds					903:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	844:911	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	6	68	theme	crosslinked	1125:1135	arg1	scaffold					1152:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	the GA crosslinked nano-cellulose scaffold	1118:1159	The results of the BET study proved that the surface area of the GA crosslinked nano-cellulose scaffold improved to129.703 m2/g.					
37068536	5	69	theme	Young	1009:1013	arg1	modulus					1017:1023	The scaffold Young's modulus	996:1023	The scaffold Young's modulus	996:1023	The scaffold Young's modulus has been increased to 86.3 MPa.					
37068536	3	70	theme	Infrared	593:600	arg1	Spectroscopy					602:613	Infrared Spectroscopy	593:613	Infrared Spectroscopy (FTIR)	593:620	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	70	theme	Infrared	593:600	arg1	FTIR					616:619	FTIR	616:619	FTIR	616:619	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	9	71	theme	textile	1397:1403	arg1	dye					1411:1413	textile black dye and methylene blue dye	1397:1436	dye	1411:1413	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	9	72	from	decrease	1521:1528	arg1	concentration					1537:1549	dye concentration	1533:1549	dye concentration	1533:1549	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	4	73	theme	scaffolds	903:911	arg1	higher					916:921	higher	916:921	higher	916:921	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	4	73	theme	scaffolds	903:911	arg1	modulus					833:839	The tensile modulus	821:839	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds	821:911	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	9	74	theme	nanocellulose	1456:1468	arg1	composites					1470:1479	nanocellulose composites	1456:1479	nanocellulose composites	1456:1479	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	2	75	theme	plasticized	451:461	arg1	nanocellulose					463:475	glycerol plasticized nanocellulose	442:475	glycerol plasticized nanocellulose derived from I. coccinea L. plant root	442:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	3	76	theme	glycerol	767:774	arg1	nano-cellulose					788:801	glycerol plasticized nano-cellulose	767:801	glycerol plasticized nano-cellulose	767:801	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	1	77	from	field	375:379	arg1	applications					340:351	applications	340:351	applications in the nanotechnology field	340:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	77	from	field	375:379	arg1	variety					329:335	a variety	327:335	a variety of applications in the nanotechnology field	327:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	2	78	theme	L.	502:503	arg1	root					511:514	I. coccinea L. plant root	490:514	I. coccinea L. plant root	490:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	3	79	theme	GA	761:762	arg1	effect					751:756	the effect	747:756	the effect of GA on glycerol plasticized nano-cellulose	747:801	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	9	80	theme	black	1405:1409	arg1	dye					1411:1413	textile black dye and methylene blue dye	1397:1436	dye	1411:1413	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	2	81	theme	I.	490:491	arg1	root					511:514	I. coccinea L. plant root	490:514	I. coccinea L. plant root	490:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	0	82	theme	coccinea	6:13	arg1	L.					15:16	Ixora coccinea L.	0:16	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.	0:85	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	9	83	theme	significant	1509:1519	arg1	decrease					1521:1528	a significant decrease	1507:1528	a significant decrease in dye concentration	1507:1549	The absorbance of textile black dye and methylene blue dye in sunlight using nanocellulose composites as photocatalyst revealed a significant decrease in dye concentration after each hour, demonstrating the composites' bio-adsorbent property.					
37068536	7	84	theme	contact	1249:1255	arg1	sites					1257:1261	contact sites	1249:1261	contact sites	1249:1261	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	2	85	theme	glutaraldehyde	419:432	arg1	impact					409:414	the impact	405:414	the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root	405:514	This article describes the impact of glutaraldehyde (GA) on glycerol plasticized nanocellulose derived from I. coccinea L. plant root.					
37068536	1	86	from	variety	329:335	arg1	field					375:379	the nanotechnology field	356:379	the nanotechnology field	356:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	3	87	theme	X-ray	623:627	arg1	XRD					649:651	XRD	649:651	XRD	649:651	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	87	theme	X-ray	623:627	arg1	Diffraction					636:646	X-ray Powder Diffraction	623:646	X-ray Powder Diffraction (XRD)	623:652	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	0	88	theme	reliable	22:29	arg1	source					31:36	A reliable source	20:36	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.	0:85	Ixora coccinea L. - A reliable source of nanocellulose for bio-adsorbent applications.					
37068536	1	89	theme	natural	183:189	arg1	resources					191:199	the world's most plentiful natural resources	156:199	the world's most plentiful natural resources	156:199	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	10	90	theme	bioengineering	1823:1836	arg1	materials					1838:1846	bioengineering materials	1823:1846	bioengineering materials	1823:1846	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	8	91	theme	scaffold	1324:1331	arg1	utility					1309:1315	the utility	1305:1315	the utility of the scaffold as a bio-adsorbent for waste water treatment	1305:1376	This enhances the utility of the scaffold as a bio-adsorbent for waste water treatment.					
37068536	1	92	theme	building	282:289	arg1	blocks					291:296	sustainable building blocks	270:296	sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field	270:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	1	93	with	friendly	245:252	arg1	properties					312:321	enhanced properties	303:321	enhanced properties	303:321	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37068536	4	94	theme	regular	952:958	arg1	78.8 MPa					985:992	78.8 MPa	985:992	78.8 MPa	985:992	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	4	94	theme	regular	952:958	arg1	scaffolds					974:982	the regular nanocellulose scaffolds	948:982	the regular nanocellulose scaffolds (78.8 MPa)	948:993	The tensile modulus of the GA-crosslinked, 2 % glycerol-plasticized nanocellulose scaffolds is higher (88.82 MPa) than that of the regular nanocellulose scaffolds (78.8 MPa).					
37068536	10	95	theme	increased	1655:1663	arg1	qualities					1713:1721	good mechanical qualities	1697:1721	good mechanical qualities	1697:1721	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	95	theme	increased	1655:1663	arg1	values					1685:1690	increased crystallinity index values	1655:1690	increased crystallinity index values	1655:1690	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	95	theme	increased	1655:1663	arg1	inertness					1644:1652	inertness	1644:1652	inertness	1644:1652	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	95	theme	increased	1655:1663	arg1	nature					1636:1641	The non-toxic nature	1622:1641	The non-toxic nature	1622:1641	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	10	95	theme	increased	1655:1663	arg1	characteristics					1733:1747	other characteristics	1727:1747	other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings	1727:1891	The non-toxic nature, inertness, increased crystallinity index values, and good mechanical qualities are other characteristics of the GA-treated nanocellulose encourages its uses as product packaging, bioengineering materials, tissue engineering, and insulation coatings.					
37068536	3	96	from	effect	751:756	arg1	nano-cellulose					788:801	glycerol plasticized nano-cellulose	767:801	glycerol plasticized nano-cellulose	767:801	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	7	97	theme	surface	1197:1203	arg1	area					1205:1208	The larger surface area	1186:1208	The larger surface area in turn	1186:1216	The larger surface area in turn results in a greater number of contact sites between consecutive fibers.					
37068536	3	98	theme	Electron	664:671	arg1	SEM					685:687	SEM	685:687	SEM	685:687	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	3	98	theme	Electron	664:671	arg1	Microscopy					673:682	Scanning Electron Microscopy	655:682	Scanning Electron Microscopy (SEM)	655:688	Using a variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Powder Diffraction (XRD), Scanning Electron Microscopy (SEM), AFM, tensile and Brunauer-Emmett-Teller (BET) analysis, the effect of GA on glycerol plasticized nano-cellulose was investigated.					
37068536	8	99	theme	water	1362:1366	arg1	treatment					1368:1376	waste water treatment	1356:1376	waste water treatment	1356:1376	This enhances the utility of the scaffold as a bio-adsorbent for waste water treatment.					
37068536	1	100	from	applications	340:351	arg1	field					375:379	the nanotechnology field	356:379	the nanotechnology field	356:379	Nanocellulose, a subset of nanomaterials made from cellulose, one of the world's most plentiful natural resources, has the potential to offer environmentally friendly, renewable, and sustainable building blocks with enhanced properties for a variety of applications in the nanotechnology field.					
37321438	0	0	theme	Camellia	87:94	arg1	waste					80:84	waste	80:84	black tea waste (Camellia sinensis)	70:104	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	0	0	theme	Camellia	87:94	arg1	sinensis					96:103	Camellia sinensis	87:103	Camellia sinensis	87:103	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	2	1	theme	acid	480:483	arg1	method					496:501	the traditional acid hydrolysis method	464:501	the traditional acid hydrolysis method	464:501	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	8	2	theme	time-saving	1445:1455	arg1	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	2	theme	time-saving	1445:1455	arg1	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	2	theme	time-saving	1445:1455	arg1	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	2	3	theme	tea	377:379	arg1	waste					381:385	black tea waste	371:385	black tea waste	371:385	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	3	4	theme	powdered	657:664	arg1	form					666:669	white powdered form	651:669	white powdered form	651:669	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	1	5	theme	abundant	251:258	arg1	source					271:276	a renewable, abundant, and cheap source	238:276	a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose	238:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	7	6	theme	89.77 	1199:1204	arg1	%					1205:1205	%	1205:1205	%	1205:1205	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	4	7	theme	tea	856:858	arg1	MCC					866:868	the synthesized tea waste MCC	840:868	the synthesized tea waste MCC	840:868	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	5	8	theme	23 μm	1007:1011	arg1	size					992:995	an average particle size	972:995	an average particle size of around 23 μm	972:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	5	9	theme	rough	941:945	arg1	structure					955:963	a short rough fibrous structure	933:963	a short rough fibrous structure having an average particle size of around 23 μm	933:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	5	10	theme	short	935:939	arg1	structure					955:963	a short rough fibrous structure	933:963	a short rough fibrous structure having an average particle size of around 23 μm	933:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	3	11	from	MCC	644:646	arg1	form					666:669	white powdered form	651:669	white powdered form	651:669	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	8	12	theme	tea	1533:1535	arg1	factories					1537:1545	tea factories	1533:1545	tea factories	1533:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	4	13	theme	synthesized	844:854	arg1	MCC					866:868	the synthesized tea waste MCC	840:868	the synthesized tea waste MCC	840:868	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	5	14	theme	fibrous	947:953	arg1	structure					955:963	a short rough fibrous structure	933:963	a short rough fibrous structure having an average particle size of around 23 μm	933:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	5	15	contain	having	965:970	arg2	size					992:995	an average particle size	972:995	an average particle size of around 23 μm	972:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	5	15	contain	having	965:970	arg1	structure					955:963	a short rough fibrous structure	933:963	a short rough fibrous structure having an average particle size of around 23 μm	933:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	6	16	theme	amorphous	1092:1100	arg1	compounds					1117:1125	all amorphous non-cellulosic compounds	1088:1125	all amorphous non-cellulosic compounds	1088:1125	The results of FTIR and XRD demonstrated unequivocally that all amorphous non-cellulosic compounds had been eliminated.					
37321438	5	17	theme	characterization	875:890	arg1	results					892:898	The characterization results	871:898	The characterization results	871:898	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	6	18	theme	XRD	1052:1054	arg1	results					1032:1038	The results	1028:1038	The results of FTIR and XRD	1028:1054	The results of FTIR and XRD demonstrated unequivocally that all amorphous non-cellulosic compounds had been eliminated.					
37321438	3	19	theme	reaction	528:535	arg1	speed					537:541	the reaction speed	524:541	the reaction speed	524:541	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	1	20	theme	tea	174:176	arg1	production					178:187	tea production	174:187	tea production processes	174:197	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	7	21	theme	waste	1182:1186	arg1	MCC					1188:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	1	22	theme	production	178:187	arg1	processes					189:197	tea production processes	174:197	tea production processes	174:197	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	0	23	theme	quick	19:23	arg1	synthesis					25:33	Microwave-assisted quick synthesis	0:33	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.	0:126	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	2	24	theme	traditional	468:478	arg1	method					496:501	the traditional acid hydrolysis method	464:501	the traditional acid hydrolysis method	464:501	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	7	25	theme	tea	1178:1180	arg1	MCC					1188:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	6	26	theme	FTIR	1043:1046	arg1	results					1032:1038	The results	1028:1038	The results of FTIR and XRD	1028:1054	The results of FTIR and XRD demonstrated unequivocally that all amorphous non-cellulosic compounds had been eliminated.					
37321438	0	27	theme	Microwave-assisted	0:17	arg1	synthesis					25:33	Microwave-assisted quick synthesis	0:33	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.	0:126	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	1	28	theme	cheap	265:269	arg1	source					271:276	a renewable, abundant, and cheap source	238:276	a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose	238:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	3	29	theme	quick	578:582	arg1	delignification					584:598	very quick delignification	573:598	very quick delignification	573:598	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	7	30	theme	thermal	1230:1236	arg1	properties					1238:1247	good thermal properties	1225:1247	good thermal properties	1225:1247	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	7	31	theme	polymer	1320:1326	arg1	composites					1328:1337	polymer composites	1320:1337	polymer composites	1320:1337	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	5	32	with	cellulose	918:926	arg1	structure					955:963	a short rough fibrous structure	933:963	a short rough fibrous structure having an average particle size of around 23 μm	933:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	5	33	theme	particle	983:990	arg1	size					992:995	an average particle size	972:995	an average particle size of around 23 μm	972:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	8	34	theme	suitable	1417:1424	arg1	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	34	theme	suitable	1417:1424	arg1	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	34	theme	suitable	1417:1424	arg1	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	1	35	theme	excellent	204:212	arg1	potential					214:222	excellent potential	204:222	excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose	204:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	7	36	theme	black	1172:1176	arg1	tea					1178:1180	black tea	1172:1180	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	4	37	theme	chemical	748:755	arg1	crystallinity					772:784	crystallinity	772:784	crystallinity	772:784	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	37	theme	chemical	748:755	arg1	functionality					757:769	the chemical functionality	744:769	the chemical functionality	744:769	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	37	theme	chemical	748:755	arg1	properties					811:820	thermal properties	803:820	thermal properties	803:820	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	37	theme	chemical	748:755	arg1	morphology					787:796	morphology	787:796	morphology	787:796	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	8	38	theme	low-cost	1461:1468	arg1	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	38	theme	low-cost	1461:1468	arg1	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	38	theme	low-cost	1461:1468	arg1	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	0	39	dep	tea	76:78	arg1	waste					80:84	waste	80:84	black tea waste (Camellia sinensis)	70:104	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	0	39	dep	tea	76:78	arg1	sinensis					96:103	Camellia sinensis	87:103	Camellia sinensis	87:103	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	2	40	theme	microwave	395:403	arg1	heating					405:411	microwave heating	395:411	microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method	395:501	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	0	41	theme	cellulose	55:63	arg1	synthesis					25:33	Microwave-assisted quick synthesis	0:33	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.	0:126	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	3	42	theme	white	651:655	arg1	form					666:669	white powdered form	651:669	white powdered form	651:669	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	7	43	theme	promising	1280:1288	arg1	material					1297:1304	a promising filler material	1278:1304	a promising filler material for preparing polymer composites	1278:1337	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	7	43	theme	promising	1280:1288	arg1	it					1266:1267	it	1266:1267	it	1266:1267	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	0	44	theme	microcrystalline	38:53	arg1	cellulose					55:63	microcrystalline cellulose	38:63	microcrystalline cellulose	38:63	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	5	45	theme	around	1000:1005	arg1	23 μm					1007:1011	around 23 μm	1000:1011	around 23 μm	1000:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	7	46	theme	filler	1290:1295	arg1	material					1297:1304	a promising filler material	1278:1304	a promising filler material for preparing polymer composites	1278:1337	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	7	46	theme	filler	1290:1295	arg1	it					1266:1267	it	1266:1267	it	1266:1267	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	0	47	theme	black	70:74	arg1	tea					76:78	black tea waste (Camellia sinensis)	70:104	black tea waste (Camellia sinensis)	70:104	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	4	48	theme	MCC	866:868	arg1	crystallinity					772:784	crystallinity	772:784	crystallinity	772:784	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	48	theme	MCC	866:868	arg1	functionality					757:769	the chemical functionality	744:769	the chemical functionality	744:769	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	48	theme	MCC	866:868	arg1	properties					811:820	thermal properties	803:820	thermal properties	803:820	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	48	theme	MCC	866:868	arg1	morphology					787:796	morphology	787:796	morphology	787:796	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	0	49	from	tea	76:78	arg1	synthesis					25:33	Microwave-assisted quick synthesis	0:33	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.	0:126	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	4	50	theme	thermal	803:809	arg1	properties					811:820	thermal properties	803:820	thermal properties	803:820	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	4	50	theme	thermal	803:809	arg1	functionality					757:769	the chemical functionality	744:769	the chemical functionality	744:769	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	2	51	theme	current	335:341	arg1	work					343:346	the current work	331:346	the current work	331:346	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	1	52	theme	microcrystalline	300:315	arg1	cellulose					317:325	microcrystalline cellulose	300:325	microcrystalline cellulose	300:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	4	53	theme	waste	860:864	arg1	MCC					866:868	the synthesized tea waste MCC	840:868	the synthesized tea waste MCC	840:868	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	0	54	from	characterization	110:125	arg1	synthesis					25:33	Microwave-assisted quick synthesis	0:33	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.	0:126	Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.					
37321438	7	55	theme	%	1205:1205	arg1	crystallinity					1207:1219	89.77 % crystallinity	1199:1219	89.77 % crystallinity	1199:1219	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	1	56	theme	Tea	128:130	arg1	wastes					132:137	Tea wastes	128:137	Tea wastes generated in the industries during tea production processes	128:197	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	1	57	theme	cellulose	317:325	arg1	extraction					286:295	the extraction	282:295	the extraction of microcrystalline cellulose	282:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
37321438	8	58	theme	energy-efficient	1427:1442	arg1	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	58	theme	energy-efficient	1427:1442	arg1	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	58	theme	energy-efficient	1427:1442	arg1	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	3	59	theme	waste	627:631	arg1	bleaching					604:612	bleaching	604:612	bleaching of black tea waste to isolate MCC in white powdered form	604:669	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	3	59	theme	waste	627:631	arg1	delignification					584:598	very quick delignification	573:598	very quick delignification	573:598	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	6	60	theme	non-cellulosic	1102:1115	arg1	compounds					1117:1125	all amorphous non-cellulosic compounds	1088:1125	all amorphous non-cellulosic compounds	1088:1125	The results of FTIR and XRD demonstrated unequivocally that all amorphous non-cellulosic compounds had been eliminated.					
37321438	8	61	theme	microwave-assisted	1351:1368	arg1	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	61	theme	microwave-assisted	1351:1368	arg1	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	61	theme	microwave-assisted	1351:1368	arg1	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	2	62	attach	isolated	357:364	arg2	MCC					349:351	MCC	349:351	MCC	349:351	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	2	62	attach	isolated	357:364	arg1	waste					381:385	black tea waste	371:385	black tea waste	371:385	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	5	63	theme	average	975:981	arg1	size					992:995	an average particle size	972:995	an average particle size of around 23 μm	972:1011	The characterization results demonstrated that cellulose with a short rough fibrous structure having an average particle size of around 23 μm was extracted.					
37321438	8	64	theme	black	1505:1509	arg1	waste					1515:1519	the black tea waste	1501:1519	the black tea waste produced in tea factories	1501:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	4	65	theme	TGA	694:696	arg1	analysis					698:705	TGA analysis	694:705	TGA analysis	694:705	FTIR, XRD, FESEM, and TGA analysis were then carried out to investigate the chemical functionality, crystallinity, morphology, and thermal properties, respectively, of the synthesized tea waste MCC.					
37321438	7	66	theme	microwave-extracted	1152:1170	arg1	MCC					1188:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC	1148:1190	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	8	67	used	used	1407:1410	arg2	bleaching					1390:1398	bleaching	1390:1398	bleaching	1390:1398	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	67	used	used	1407:1410	arg2	delignification					1370:1384	microwave-assisted delignification	1351:1384	microwave-assisted delignification	1351:1384	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	8	67	used	used	1407:1410	arg2	method					1470:1475	a suitable, energy-efficient, time-saving and low-cost method	1415:1475	a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories	1415:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	7	68	theme	good	1225:1228	arg1	properties					1238:1247	good thermal properties	1225:1247	good thermal properties	1225:1247	The microwave-extracted black tea waste MCC showed 89.77 % crystallinity and good thermal properties, indicating that it could be a promising filler material for preparing polymer composites.					
37321438	3	69	theme	black	617:621	arg1	waste					627:631	black tea waste	617:631	black tea waste	617:631	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	2	70	theme	black	371:375	arg1	tea					377:379	black tea	371:379	black tea waste	371:385	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	2	71	theme	hydrolysis	485:494	arg1	method					496:501	the traditional acid hydrolysis method	464:501	the traditional acid hydrolysis method	464:501	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	8	72	theme	tea	1511:1513	arg1	waste					1515:1519	the black tea waste	1501:1519	the black tea waste produced in tea factories	1501:1545	Therefore, microwave-assisted delignification and bleaching can be used as a suitable, energy-efficient, time-saving and low-cost method for extracting MCC from the black tea waste produced in tea factories.					
37321438	3	73	theme	tea	623:625	arg1	waste					627:631	black tea waste	617:631	black tea waste	617:631	Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.					
37321438	2	74	theme	conventional	430:441	arg1	heating					443:449	conventional heating	430:449	conventional heating	430:449	In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method.					
37321438	1	75	theme	renewable	240:248	arg1	source					271:276	a renewable, abundant, and cheap source	238:276	a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose	238:325	Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose.					
36174861	0	0	theme	dye	90:92	arg1	adsorption					61:70	efficient adsorption	51:70	efficient adsorption of methylene blue dye	51:92	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	2	1	theme	polyacrylic	506:516	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	2	2	theme	good	343:346	arg1	reusability					348:358	good reusability	343:358	good reusability	343:358	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	0	3	theme	blue	85:88	arg1	dye					90:92	methylene blue dye	75:92	methylene blue dye	75:92	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	7	4	theme	hydrogen	1149:1156	arg1	bonding					1158:1164	hydrogen bonding	1149:1164	hydrogen bonding	1149:1164	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	2	5	link	cross-linked	428:439	arg1	polyvinylamine					441:454	chitosan cross-linked polyvinylamine	419:454	chitosan cross-linked polyvinylamine	419:454	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	1	6	theme	large	149:153	arg1	amount					155:160	a large amount	147:160	a large amount of dyeing wastewater discharge	147:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	1	6	theme	large	149:153	arg1	discharge					183:191	dyeing wastewater discharge	165:191	dyeing wastewater discharge	165:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	2	7	theme	dual-network	262:273	arg1	hydrogel					286:293	a dual-network, composite hydrogel	260:293	a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity	260:389	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	3	8	theme	mechanical	591:600	arg1	properties					602:611	the hydrogel excellent mechanical properties	568:611	the hydrogel excellent mechanical properties	568:611	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	2	9	with	adsorbent	295:303	arg1	properties					331:340	excellent mechanical properties	310:340	excellent mechanical properties	310:340	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	2	9	with	adsorbent	295:303	arg1	capacity					382:389	large adsorption capacity	365:389	large adsorption capacity	365:389	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	2	9	with	adsorbent	295:303	arg1	reusability					348:358	good reusability	343:358	good reusability	343:358	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	3	10	theme	hydrogel	572:579	arg1	properties					602:611	the hydrogel excellent mechanical properties	568:611	the hydrogel excellent mechanical properties	568:611	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	2	11	dep	dual-network	262:273	arg1	composite					276:284	composite	276:284	composite	276:284	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	7	12	theme	blue	1227:1230	arg1	molecules					1232:1240	methylene blue molecules	1217:1240	methylene blue molecules	1217:1240	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	7	13	theme	hydrogels	1203:1211	arg1	groups					1189:1194	the functional groups	1174:1194	the functional groups of the hydrogels	1174:1211	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	7	13	theme	hydrogels	1203:1211	arg1	hydrogels					1203:1211	the hydrogels	1199:1211	the hydrogels	1199:1211	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	8	14	theme	synthesized	1300:1310	arg1	adsorbent					1362:1370	adsorbent	1362:1370	adsorbent	1362:1370	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	8	14	theme	synthesized	1300:1310	arg1	hydrogels					1322:1330	the synthesized composite hydrogels	1296:1330	the synthesized composite hydrogels	1296:1330	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	8	15	theme	blue	1401:1404	arg1	dye					1406:1408	methylene blue dye	1391:1408	methylene blue dye	1391:1408	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	2	16	theme	large	365:369	arg1	capacity					382:389	large adsorption capacity	365:389	large adsorption capacity	365:389	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	4	17	theme	adsorption	681:690	arg1	capacity					692:699	The adsorption capacity	677:699	The adsorption capacity of methylene blue on hydrogel	677:729	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	4	17	theme	adsorption	681:690	arg1	596.14 mg/g					741:751	596.14 mg/g	741:751	596.14 mg/g	741:751	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	7	18	theme	functional	1178:1187	arg1	groups					1189:1194	the functional groups	1174:1194	the functional groups of the hydrogels	1174:1211	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	7	18	theme	functional	1178:1187	arg1	hydrogels					1203:1211	the hydrogels	1199:1211	the hydrogels	1199:1211	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	6	19	theme	adsorption	901:910	arg1	behavior					912:919	The adsorption behavior	897:919	The adsorption behavior	897:919	The adsorption behavior was well fitted by Pseudo-second-order kinetics and the Langmuir equation, indicating that the hydrogel was chemisorbed to the dye as a monolayer.					
36174861	5	20	theme	good	799:802	arg1	reusability					804:814	good reusability	799:814	good reusability	799:814	In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles.					
36174861	5	21	theme	adsorption	827:836	arg1	efficiency					838:847	their adsorption efficiency	821:847	their adsorption efficiency	821:847	In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles.					
36174861	2	22	theme	adsorption	371:380	arg1	capacity					382:389	large adsorption capacity	365:389	large adsorption capacity	365:389	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	0	23	theme	dual	15:18	arg1	hydrogel					38:45	Chitosan-based dual network composite hydrogel	0:45	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.	0:93	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	2	24	theme	cross-linked	493:504	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	7	25	theme	good	1261:1264	arg1	capacity					1277:1284	the good adsorption capacity	1257:1284	the good adsorption capacity	1257:1284	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	7	26	theme	adsorption	1266:1275	arg1	capacity					1277:1284	the good adsorption capacity	1257:1284	the good adsorption capacity	1257:1284	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	2	27	theme	adsorbent	295:303	arg1	hydrogel					286:293	a dual-network, composite hydrogel	260:293	a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity	260:389	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	1	28	theme	dyeing	165:170	arg1	discharge					183:191	dyeing wastewater discharge	165:191	dyeing wastewater discharge	165:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	0	29	theme	Chitosan-based	0:13	arg1	hydrogel					38:45	Chitosan-based dual network composite hydrogel	0:45	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.	0:93	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	7	30	theme	electrostatic	1118:1130	arg1	interactions					1132:1143	the electrostatic interactions	1114:1143	the electrostatic interactions	1114:1143	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	1	31	theme	wastewater	172:181	arg1	discharge					183:191	dyeing wastewater discharge	165:191	dyeing wastewater discharge	165:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	0	32	theme	composite	28:36	arg1	hydrogel					38:45	Chitosan-based dual network composite hydrogel	0:45	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.	0:93	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	8	33	used	used	1341:1344	arg2	adsorbent					1362:1370	adsorbent	1362:1370	adsorbent	1362:1370	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	8	33	used	used	1341:1344	arg2	hydrogels					1322:1330	the synthesized composite hydrogels	1296:1330	the synthesized composite hydrogels	1296:1330	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	3	34	theme	excellent	581:589	arg1	properties					602:611	the hydrogel excellent mechanical properties	568:611	the hydrogel excellent mechanical properties	568:611	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	1	35	theme	discharge	183:191	arg1	amount					155:160	a large amount	147:160	a large amount of dyeing wastewater discharge	147:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	1	35	theme	discharge	183:191	arg1	discharge					183:191	dyeing wastewater discharge	165:191	dyeing wastewater discharge	165:191	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	0	36	theme	network	20:26	arg1	hydrogel					38:45	Chitosan-based dual network composite hydrogel	0:45	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.	0:93	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	8	37	theme	textile	1429:1435	arg1	wastewater					1446:1455	textile industry wastewater	1429:1455	textile industry wastewater	1429:1455	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	1	38	theme	rapid	104:108	arg1	development					110:120	the rapid development	100:120	the rapid development of the textile industry	100:144	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	3	39	theme	dual	536:539	arg1	network					555:561	The dual cross-linking network	532:561	The dual cross-linking network	532:561	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	2	40	theme	N'-methylenebisacrylamide	467:491	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	4	41	from	capacity	692:699	arg1	hydrogel					722:729	hydrogel	722:729	hydrogel	722:729	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	7	42	theme	adsorption	1072:1081	arg1	analysis					1093:1100	The adsorption mechanism analysis	1068:1100	The adsorption mechanism analysis	1068:1100	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	8	43	theme	industry	1437:1444	arg1	wastewater					1446:1455	textile industry wastewater	1429:1455	textile industry wastewater	1429:1455	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	8	44	from	wastewater	1446:1455	arg1	removal					1380:1386	the removal	1376:1386	the removal	1376:1386	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	4	45	theme	blue	714:717	arg1	methylene					704:712	methylene blue	704:717	methylene blue	704:717	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	6	46	theme	Langmuir	977:984	arg1	equation					986:993	the Langmuir equation	973:993	the Langmuir equation	973:993	The adsorption behavior was well fitted by Pseudo-second-order kinetics and the Langmuir equation, indicating that the hydrogel was chemisorbed to the dye as a monolayer.					
36174861	7	47	theme	mechanism	1083:1091	arg1	analysis					1093:1100	The adsorption mechanism analysis	1068:1100	The adsorption mechanism analysis	1068:1100	The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity.					
36174861	2	48	theme	cross-linked	428:439	arg1	polyvinylamine					441:454	chitosan cross-linked polyvinylamine	419:454	chitosan cross-linked polyvinylamine	419:454	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	5	49	from	%	867:867	arg1	cycles					889:894	five consecutive cycles	872:894	five consecutive cycles	872:894	In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles.					
36174861	1	50	theme	great	204:208	arg1	harm					210:213	great harm	204:213	great harm to the ecological environment	204:243	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	2	51	theme	N	465:465	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	5	52	theme	prepared	771:778	arg1	hydrogel					780:787	the prepared hydrogel	767:787	the prepared hydrogel	767:787	In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles.					
36174861	3	53	theme	maximum	618:624	arg1	stress					634:639	maximum tensile stress	618:639	maximum tensile stress	618:639	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	2	54	link	cross-linked	493:504	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	0	55	theme	efficient	51:59	arg1	adsorption					61:70	efficient adsorption	51:70	efficient adsorption of methylene blue dye	51:92	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	3	56	theme	tensile	626:632	arg1	stress					634:639	maximum tensile stress	618:639	maximum tensile stress	618:639	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	2	57	theme	mechanical	320:329	arg1	properties					331:340	excellent mechanical properties	310:340	excellent mechanical properties	310:340	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	8	58	theme	dye	1406:1408	arg1	removal					1380:1386	the removal	1376:1386	the removal	1376:1386	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	4	59	theme	methylene	704:712	arg1	capacity					692:699	The adsorption capacity	677:699	The adsorption capacity of methylene blue on hydrogel	677:729	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	4	59	theme	methylene	704:712	arg1	596.14 mg/g					741:751	596.14 mg/g	741:751	596.14 mg/g	741:751	The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g.					
36174861	2	60	theme	excellent	310:318	arg1	properties					331:340	excellent mechanical properties	310:340	excellent mechanical properties	310:340	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	8	61	theme	methylene	1391:1399	arg1	dye					1406:1408	methylene blue dye	1391:1408	methylene blue dye	1391:1408	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	1	62	theme	textile	129:135	arg1	industry					137:144	the textile industry	125:144	the textile industry	125:144	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	0	63	theme	methylene	75:83	arg1	dye					90:92	methylene blue dye	75:92	methylene blue dye	75:92	Chitosan-based dual network composite hydrogel for efficient adsorption of methylene blue dye.					
36174861	8	64	theme	composite	1312:1320	arg1	adsorbent					1362:1370	adsorbent	1362:1370	adsorbent	1362:1370	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	8	64	theme	composite	1312:1320	arg1	hydrogels					1322:1330	the synthesized composite hydrogels	1296:1330	the synthesized composite hydrogels	1296:1330	Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.					
36174861	1	65	theme	industry	137:144	arg1	development					110:120	the rapid development	100:120	the rapid development of the textile industry	100:144	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
36174861	5	66	theme	consecutive	877:887	arg1	cycles					889:894	five consecutive cycles	872:894	five consecutive cycles	872:894	In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles.					
36174861	2	67	theme	acid	518:521	arg1	network					523:529	the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network	461:529	network	523:529	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	6	68	theme	Pseudo-second-order	940:958	arg1	kinetics					960:967	Pseudo-second-order kinetics	940:967	Pseudo-second-order kinetics	940:967	The adsorption behavior was well fitted by Pseudo-second-order kinetics and the Langmuir equation, indicating that the hydrogel was chemisorbed to the dye as a monolayer.					
36174861	2	69	theme	chitosan	419:426	arg1	polyvinylamine					441:454	chitosan cross-linked polyvinylamine	419:454	chitosan cross-linked polyvinylamine	419:454	In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N,N'-methylenebisacrylamide cross-linked polyacrylic acid network.					
36174861	3	70	theme	cross-linking	541:553	arg1	network					555:561	The dual cross-linking network	532:561	The dual cross-linking network	532:561	The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %.					
36174861	1	71	theme	ecological	222:231	arg1	environment					233:243	the ecological environment	218:243	the ecological environment	218:243	With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment.					
35489626	6	0	theme	NPs	938:940	arg1	emulsion					952:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	1	1	from	Limitations	210:220	arg1	effectiveness					243:255	effectiveness	243:255	effectiveness	243:255	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	1	1	from	Limitations	210:220	arg1	compatibility					225:237	compatibility	225:237	compatibility	225:237	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	2	2	theme	Pickering	407:415	arg1	hydrogels					436:444	Pickering emulsion composite hydrogels	407:444	Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR)	407:596	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	10	3	theme	mRNA	1337:1340	arg1	levels					1342:1347	the mRNA levels	1333:1347	the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group	1333:1396	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	2	4	theme	Pickering	537:545	arg1	emulsions					547:555	Pickering emulsions	537:555	Pickering emulsions	537:555	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	6	5	theme	CMCS-SA	930:936	arg1	emulsion					952:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	11	6	theme	wound	1590:1594	arg1	management					1601:1610	wound care management	1590:1610	wound care management	1590:1610	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	6	7	theme	%	928:928	arg1	emulsion					952:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	9	8	theme	wound	1245:1249	arg1	healing					1251:1257	wound healing	1245:1257	wound healing	1245:1257	Moreover, the CMCS-SA-PLX-CUR hydrogels improved wound healing and increased expression of Ki67 and CD31.					
35489626	4	9	theme	Pickering	684:692	arg1	emulsion					694:701	Pickering emulsion	684:701	Pickering emulsion	684:701	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	4	10	dep	strength	793:800	arg1	change					802:807	change	802:807	change	802:807	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	6	11	theme	0.6	925:927	arg1	%					928:928	%	928:928	%	928:928	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	11	12	theme	hydrogels	1527:1535	arg1	promising					1541:1549	promising	1541:1549	promising	1541:1549	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	11	12	theme	hydrogels	1527:1535	arg1	potentials					1497:1506	the potentials	1493:1506	the potentials of CMCS-SA-PLX-CUR hydrogels	1493:1535	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	10	13	theme	TGF-β1	1362:1367	arg1	levels					1342:1347	the mRNA levels	1333:1347	the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group	1333:1396	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	0	14	theme	emulsion	132:139	arg1	hydrogels					141:149	Pickering emulsion hydrogels	122:149	Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing	122:207	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	1	15	from	emulsions	348:356	arg1	dressing					367:374	wound dressing	361:374	wound dressing	361:374	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	10	16	theme	TGF-β3	1443:1448	arg1	levels					1433:1438	the mRNA levels	1424:1438	the mRNA levels of TGF-β3	1424:1448	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	11	17	theme	CMCS-SA-PLX-CUR	1511:1525	arg1	hydrogels					1527:1535	CMCS-SA-PLX-CUR hydrogels	1511:1535	CMCS-SA-PLX-CUR hydrogels	1511:1535	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	2	18	theme	carboxymethyl	455:467	arg1	CMCS-SA					497:503	CMCS-SA	497:503	CMCS-SA	497:503	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	2	18	theme	carboxymethyl	455:467	arg1	chitosan					469:476	carboxymethyl chitosan	455:476	carboxymethyl chitosan	455:476	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	0	19	theme	Pickering	122:130	arg1	hydrogels					141:149	Pickering emulsion hydrogels	122:149	Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing	122:207	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	4	20	theme	ionic	787:791	arg1	strength					793:800	ionic strength change	787:807	ionic strength change	787:807	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	10	21	theme	α-SMA	1352:1356	arg1	levels					1342:1347	the mRNA levels	1333:1347	the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group	1333:1396	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	8	22	contain	has	1115:1117	arg1	hydrogels					1105:1113	This composite hydrogels	1090:1113	This composite hydrogels	1090:1113	This composite hydrogels has antibacterial properties against Escherichia coli and Staphylococcus aureus.					
35489626	8	22	contain	has	1115:1117	arg2	properties					1133:1142	antibacterial properties	1119:1142	antibacterial properties	1119:1142	This composite hydrogels has antibacterial properties against Escherichia coli and Staphylococcus aureus.					
35489626	0	23	theme	alginate	86:93	arg1	construction					17:28	construction	17:28	construction	17:28	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	0	23	theme	alginate	86:93	arg1	characterization					34:49	characterization	34:49	characterization	34:49	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	9	24	theme	Ki67	1287:1290	arg1	expression					1273:1282	expression	1273:1282	expression of Ki67 and CD31	1273:1299	Moreover, the CMCS-SA-PLX-CUR hydrogels improved wound healing and increased expression of Ki67 and CD31.					
35489626	3	25	theme	CMCS-SA	599:605	arg1	NPs					607:609	CMCS-SA NPs	599:609	CMCS-SA NPs	599:609	CMCS-SA NPs were prepared and used to stabilize Pickering emulsion.					
35489626	11	26	theme	present	1465:1471	arg1	study					1473:1477	The present study	1461:1477	The present study	1461:1477	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	4	27	theme	emulsion	694:701	arg1	stability					671:679	The stability	667:679	The stability of Pickering emulsion	667:701	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	4	27	theme	emulsion	694:701	arg1	sensitive					774:782	sensitive	774:782	sensitive	774:782	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	1	28	theme	Pickering	338:346	arg1	emulsions					348:356	Pickering emulsions	338:356	Pickering emulsions in wound dressing	338:374	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	9	29	theme	CD31	1296:1299	arg1	expression					1273:1282	expression	1273:1282	expression of Ki67 and CD31	1273:1299	Moreover, the CMCS-SA-PLX-CUR hydrogels improved wound healing and increased expression of Ki67 and CD31.					
35489626	10	30	from	levels	1342:1347	arg1	group					1392:1396	the CMCS-SA-PLX-CUR group	1372:1396	the CMCS-SA-PLX-CUR group	1372:1396	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	10	31	theme	CMCS-SA-PLX-CUR	1376:1390	arg1	group					1392:1396	the CMCS-SA-PLX-CUR group	1372:1396	the CMCS-SA-PLX-CUR group	1372:1396	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	2	32	theme	alginate	487:494	arg1	NPs					521:523	NPs	521:523	NPs	521:523	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	2	32	theme	alginate	487:494	arg1	nanoparticles					506:518	carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles	455:518	carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR)	455:596	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	0	33	theme	construction	17:28	arg1	Investigation					0:12	Investigation	0:12	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate	0:93	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	6	34	theme	curcumin	990:997	arg1	release					979:985	controlled release	968:985	controlled release of curcumin	968:997	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	8	35	theme	antibacterial	1119:1131	arg1	properties					1133:1142	antibacterial properties	1119:1142	antibacterial properties	1119:1142	This composite hydrogels has antibacterial properties against Escherichia coli and Staphylococcus aureus.					
35489626	7	36	theme	dense	1073:1077	arg1	structure					1079:1087	dense structure	1073:1087	dense structure	1073:1087	The CMCS-SA-PLX-CUR hydrogels also exhibited smooth surface and dense structure.					
35489626	5	37	theme	Pickering	815:823	arg1	emulsion					825:832	This Pickering emulsion	810:832	This Pickering emulsion	810:832	This Pickering emulsion remained stable at various temperatures.					
35489626	2	38	theme	sodium	480:485	arg1	alginate					487:494	sodium alginate	480:494	sodium alginate	480:494	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	8	39	theme	composite	1095:1103	arg1	hydrogels					1105:1113	This composite hydrogels	1090:1113	This composite hydrogels	1090:1113	This composite hydrogels has antibacterial properties against Escherichia coli and Staphylococcus aureus.					
35489626	0	40	theme	characterization	34:49	arg1	Investigation					0:12	Investigation	0:12	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate	0:93	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	1	41	theme	wound	361:365	arg1	dressing					367:374	wound dressing	361:374	wound dressing	361:374	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	0	42	theme	curcumin	155:162	arg1	encapsulation					164:176	curcumin encapsulation	155:176	curcumin encapsulation	155:176	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	7	43	theme	smooth	1054:1059	arg1	surface					1061:1067	smooth surface	1054:1067	smooth surface	1054:1067	The CMCS-SA-PLX-CUR hydrogels also exhibited smooth surface and dense structure.					
35489626	2	44	theme	chitosan	469:476	arg1	NPs					521:523	NPs	521:523	NPs	521:523	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	2	44	theme	chitosan	469:476	arg1	nanoparticles					506:518	carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles	455:518	carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR)	455:596	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	0	45	theme	chitosan	68:75	arg1	construction					17:28	construction	17:28	construction	17:28	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	0	45	theme	chitosan	68:75	arg1	characterization					34:49	characterization	34:49	characterization	34:49	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	6	46	theme	controlled	968:977	arg1	release					979:985	controlled release	968:985	controlled release of curcumin	968:997	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	0	47	theme	accelerating	182:193	arg1	healing					201:207	accelerating wound healing	182:207	accelerating wound healing	182:207	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	4	48	theme	concentration	737:749	arg1	increase					721:728	the increase	717:728	the increase of the concentration of NPs	717:756	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	0	49	theme	carboxymethyl	54:66	arg1	chitosan					68:75	carboxymethyl chitosan	54:75	carboxymethyl chitosan	54:75	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	9	50	theme	CMCS-SA-PLX-CUR	1210:1224	arg1	hydrogels					1226:1234	the CMCS-SA-PLX-CUR hydrogels	1206:1234	the CMCS-SA-PLX-CUR hydrogels	1206:1234	Moreover, the CMCS-SA-PLX-CUR hydrogels improved wound healing and increased expression of Ki67 and CD31.					
35489626	4	51	theme	NPs	754:756	arg1	concentration					737:749	the concentration	733:749	the concentration of NPs	733:756	The stability of Pickering emulsion improved with the increase of the concentration of NPs, and was highly sensitive to ionic strength change.					
35489626	1	52	theme	bioactive	271:279	arg1	compounds					281:289	bioactive compounds	271:289	bioactive compounds	271:289	Limitations in compatibility and effectiveness in delivering bioactive compounds often make it prohibitively difficult to apply Pickering emulsions in wound dressing.					
35489626	0	53	theme	wound	195:199	arg1	healing					201:207	accelerating wound healing	182:207	accelerating wound healing	182:207	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	3	54	theme	Pickering	647:655	arg1	emulsion					657:664	Pickering emulsion	647:664	Pickering emulsion	647:664	CMCS-SA NPs were prepared and used to stabilize Pickering emulsion.					
35489626	7	55	theme	CMCS-SA-PLX-CUR	1013:1027	arg1	hydrogels					1029:1037	The CMCS-SA-PLX-CUR hydrogels	1009:1037	The CMCS-SA-PLX-CUR hydrogels	1009:1037	The CMCS-SA-PLX-CUR hydrogels also exhibited smooth surface and dense structure.					
35489626	3	56	used	used	629:632	arg2	NPs					607:609	CMCS-SA NPs	599:609	CMCS-SA NPs	599:609	CMCS-SA NPs were prepared and used to stabilize Pickering emulsion.					
35489626	10	57	theme	RT-qPCR	1302:1308	arg1	results					1310:1316	RT-qPCR results	1302:1316	RT-qPCR results	1302:1316	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	0	58	theme	sodium	79:84	arg1	alginate					86:93	sodium alginate	79:93	sodium alginate	79:93	Investigation of construction and characterization of carboxymethyl chitosan - sodium alginate nanoparticles to stabilize Pickering emulsion hydrogels for curcumin encapsulation and accelerating wound healing.					
35489626	11	59	theme	care	1596:1599	arg1	management					1601:1610	wound care management	1590:1610	wound care management	1590:1610	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	5	60	theme	various	853:859	arg1	temperatures					861:872	various temperatures	853:872	various temperatures	853:872	This Pickering emulsion remained stable at various temperatures.					
35489626	2	61	theme	composite	426:434	arg1	hydrogels					436:444	Pickering emulsion composite hydrogels	407:444	Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR)	407:596	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35489626	11	62	theme	bioactive	1565:1573	arg1	components					1575:1584	bioactive components	1565:1584	bioactive components	1565:1584	The present study suggests that the potentials of CMCS-SA-PLX-CUR hydrogels are promising in protecting bioactive components and wound care management.					
35489626	6	63	theme	Pickering	942:950	arg1	emulsion					952:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	0.6% CMCS-SA NPs Pickering emulsion	925:959	After curcumin were introduced into the emulsion, 0.6% CMCS-SA NPs Pickering emulsion showed controlled release of curcumin in vitro.					
35489626	10	64	theme	mRNA	1428:1431	arg1	levels					1433:1438	the mRNA levels	1424:1438	the mRNA levels of TGF-β3	1424:1448	RT-qPCR results indicated that the mRNA levels of α-SMA and TGF-β1 in the CMCS-SA-PLX-CUR group were downregulated, while the mRNA levels of TGF-β3 increased.					
35489626	2	65	theme	emulsion	417:424	arg1	hydrogels					436:444	Pickering emulsion composite hydrogels	407:444	Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR)	407:596	In this research, we prepared Pickering emulsion composite hydrogels based on carboxymethyl chitosan - sodium alginate (CMCS-SA) nanoparticles (NPs) stabilized Pickering emulsions, poloxamer 407 (PLX), and curcumin (CUR).					
35278729	4	0	theme	composite	661:669	arg1	film					671:674	The composite film	657:674	The composite film	657:674	The composite film displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.					
35278729	1	1	theme	aqueous	221:227	arg1	solution					229:236	aqueous solution	221:236	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	2	2	theme	parameters	343:352	arg1	Influences					319:328	Influences	319:328	Influences of preparing parameters on properties, especially stability, of primary and double emulsions	319:421	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	6	3	theme	pronounced	880:889	arg1	interaction					891:901	no pronounced interaction	877:901	no pronounced interaction between the added active agents and chitosan	877:946	FTIR found no pronounced interaction between the added active agents and chitosan.					
35278729	1	4	theme	chitosan	286:293	arg1	film					295:298	chitosan film	286:298	chitosan film	286:298	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	4	5	theme	Gram-negative	743:755	arg1	bacteria					757:764	both Gram-positive and Gram-negative bacteria	720:764	both Gram-positive and Gram-negative bacteria	720:764	The composite film displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.					
35278729	8	6	with	fillets	1074:1080	arg1	film					1101:1104	the composite film	1087:1104	the composite film	1087:1104	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	0	7	theme	chitosan	80:87	arg1	film					89:92	a chitosan film	78:92	a chitosan film to improve the protection of fresh fish meat	78:137	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	1	8	theme	nisin	241:245	arg1	solution					229:236	aqueous solution	221:236	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	2	9	theme	antibacterial	459:471	arg1	activity					473:480	more persistent antibacterial activity	443:480	more persistent antibacterial activity	443:480	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	8	10	theme	fish	1148:1151	arg1	fillets					1153:1159	fish fillets	1148:1159	fish fillets	1148:1159	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	1	11	theme	novel	142:146	arg1	film					165:168	A novel edible composite film	140:168	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film	140:298	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	2	12	theme	persistent	448:457	arg1	activity					473:480	more persistent antibacterial activity	443:480	more persistent antibacterial activity	443:480	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	8	13	theme	fillets	1153:1159	arg1	life					1140:1143	the shelf life	1130:1143	the shelf life of fish fillets	1130:1159	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	1	14	theme	edible	148:153	arg1	film					165:168	A novel edible composite film	140:168	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film	140:298	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	0	15	theme	novel	2:6	arg1	film					25:28	A novel composite edible film	0:28	A novel composite edible film	0:28	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	1	16	theme	composite	155:163	arg1	film					165:168	A novel edible composite film	140:168	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film	140:298	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	5	17	theme	aggregation	788:798	arg1	sign					780:783	a sign	778:783	a sign of aggregation of some emulsion droplets near the surface of the composite film	778:863	SEM showed a sign of aggregation of some emulsion droplets near the surface of the composite film.					
35278729	7	18	from	temperature	1046:1056	arg1	stability					1016:1024	the thermal stability	1004:1024	the thermal stability of the film at high temperature	1004:1056	TGA proved that the double emulsion helped to increase the thermal stability of the film at high temperature.					
35278729	5	19	theme	composite	850:858	arg1	film					860:863	the composite film	846:863	the composite film	846:863	SEM showed a sign of aggregation of some emulsion droplets near the surface of the composite film.					
35278729	0	20	theme	edible	18:23	arg1	film					25:28	A novel composite edible film	0:28	A novel composite edible film	0:28	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	8	21	theme	optimal	1176:1182	arg1	potency					1184:1190	optimal potency	1176:1190	optimal potency	1176:1190	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	4	22	theme	Gram-positive	725:737	arg1	bacteria					757:764	both Gram-positive and Gram-negative bacteria	720:764	both Gram-positive and Gram-negative bacteria	720:764	The composite film displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.					
35278729	5	23	theme	emulsion	808:815	arg1	droplets					817:824	some emulsion droplets	803:824	some emulsion droplets	803:824	SEM showed a sign of aggregation of some emulsion droplets near the surface of the composite film.					
35278729	0	24	theme	composite	8:16	arg1	film					25:28	A novel composite edible film	0:28	A novel composite edible film	0:28	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	7	25	theme	high	1041:1044	arg1	temperature					1046:1056	high temperature	1041:1056	high temperature	1041:1056	TGA proved that the double emulsion helped to increase the thermal stability of the film at high temperature.					
35278729	1	26	dep	W1	217:218	arg1	solution					229:236	aqueous solution	221:236	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	1	26	dep	W1	217:218	arg1	carvacrol					270:278	carvacrol	270:278	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	1	26	dep	W1	217:218	arg1	water					252:256	water	252:256	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	1	26	dep	W1	217:218	arg1	phase					263:267	oil phase	259:267	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	1	26	dep	W1	217:218	arg1	W2					248:249	W2	248:249	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	3	27	theme	tension	507:513	arg1	strength					515:522	The film's tension strength	496:522	The film's tension strength	496:522	The film's tension strength was increased by incorporating double emulsion at low concentration, but its oxygen permeability increased after this incorporation.					
35278729	5	28	theme	droplets	817:824	arg1	aggregation					788:798	aggregation	788:798	aggregation of some emulsion droplets near the surface of the composite film	788:863	SEM showed a sign of aggregation of some emulsion droplets near the surface of the composite film.					
35278729	0	29	theme	fresh	123:127	arg1	meat					134:137	fresh fish meat	123:137	fresh fish meat	123:137	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	3	30	theme	oxygen	601:606	arg1	permeability					608:619	its oxygen permeability	597:619	its oxygen permeability	597:619	The film's tension strength was increased by incorporating double emulsion at low concentration, but its oxygen permeability increased after this incorporation.					
35278729	2	31	theme	emulsions	413:421	arg1	properties					357:366	properties	357:366	properties	357:366	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	2	31	theme	emulsions	413:421	arg1	stability					380:388	stability	380:388	especially stability	369:388	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	7	32	theme	film	1033:1036	arg1	stability					1016:1024	the thermal stability	1004:1024	the thermal stability of the film at high temperature	1004:1056	TGA proved that the double emulsion helped to increase the thermal stability of the film at high temperature.					
35278729	1	33	dep	emulsion	207:214	arg1	W1					217:218	W1	217:218	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	3	34	theme	double	555:560	arg1	emulsion					562:569	double emulsion	555:569	double emulsion	555:569	The film's tension strength was increased by incorporating double emulsion at low concentration, but its oxygen permeability increased after this incorporation.					
35278729	1	35	theme	W1/O/W2	199:205	arg1	emulsion					207:214	W1/O/W2 emulsion	199:214	W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol)	199:279	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	2	36	theme	double	406:411	arg1	emulsions					413:421	primary and double emulsions	394:421	primary and double emulsions	394:421	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	1	37	theme	oil	259:261	arg1	phase					263:267	oil phase	259:267	W1: aqueous solution of nisin; W2: water; oil phase: carvacrol	217:278	A novel edible composite film constructed by incorporating W1/O/W2 emulsion (W1: aqueous solution of nisin; W2: water; oil phase: carvacrol) into chitosan film was characterized.					
35278729	0	38	theme	meat	134:137	arg1	protection					109:118	the protection	105:118	the protection of fresh fish meat	105:137	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	2	39	from	Influences	319:328	arg1	properties					357:366	properties	357:366	properties	357:366	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	2	39	from	Influences	319:328	arg1	stability					380:388	stability	380:388	especially stability	369:388	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	8	40	theme	Coating	1059:1065	arg1	fillets					1074:1080	Coating salmon fillets	1059:1080	Coating salmon fillets with the composite film	1059:1104	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	6	41	theme	added	915:919	arg1	agents					928:933	the added active agents	911:933	the added active agents	911:933	FTIR found no pronounced interaction between the added active agents and chitosan.					
35278729	0	42	theme	fish	129:132	arg1	meat					134:137	fresh fish meat	123:137	fresh fish meat	123:137	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	8	43	theme	salmon	1067:1072	arg1	fillets					1074:1080	Coating salmon fillets	1059:1080	Coating salmon fillets with the composite film	1059:1104	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	8	44	theme	shelf	1134:1138	arg1	life					1140:1143	the shelf life	1130:1143	the shelf life of fish fillets	1130:1159	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	3	45	theme	low	574:576	arg1	concentration					578:590	low concentration	574:590	low concentration	574:590	The film's tension strength was increased by incorporating double emulsion at low concentration, but its oxygen permeability increased after this incorporation.					
35278729	4	46	theme	inhibitory	698:707	arg1	effects					709:715	significant inhibitory effects	686:715	significant inhibitory effects	686:715	The composite film displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.					
35278729	7	47	theme	thermal	1008:1014	arg1	stability					1016:1024	the thermal stability	1004:1024	the thermal stability of the film at high temperature	1004:1056	TGA proved that the double emulsion helped to increase the thermal stability of the film at high temperature.					
35278729	8	48	theme	composite	1091:1099	arg1	film					1101:1104	the composite film	1087:1104	the composite film	1087:1104	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	4	49	theme	significant	686:696	arg1	effects					709:715	significant inhibitory effects	686:715	significant inhibitory effects	686:715	The composite film displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.					
35278729	8	50	theme	fish	1206:1209	arg1	fillets					1211:1217	fish fillets	1206:1217	fish fillets	1206:1217	Coating salmon fillets with the composite film significantly increased the shelf life of fish fillets, demonstrating optimal potency in preserving fish fillets.					
35278729	7	51	theme	double	969:974	arg1	emulsion					976:983	the double emulsion	965:983	the double emulsion	965:983	TGA proved that the double emulsion helped to increase the thermal stability of the film at high temperature.					
35278729	5	52	theme	film	860:863	arg1	surface					835:841	the surface	831:841	the surface of the composite film	831:863	SEM showed a sign of aggregation of some emulsion droplets near the surface of the composite film.					
35278729	2	53	theme	preparing	333:341	arg1	parameters					343:352	preparing parameters	333:352	preparing parameters	333:352	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	0	54	theme	W/O/W	58:62	arg1	emulsion					64:71	W/O/W emulsion	58:71	W/O/W emulsion	58:71	A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat.					
35278729	2	55	theme	primary	394:400	arg1	emulsions					413:421	primary and double emulsions	394:421	primary and double emulsions	394:421	Influences of preparing parameters on properties, especially stability, of primary and double emulsions were evaluated, and more persistent antibacterial activity was achieved.					
35278729	6	56	theme	active	921:926	arg1	agents					928:933	the added active agents	911:933	the added active agents	911:933	FTIR found no pronounced interaction between the added active agents and chitosan.					
36919715	4	0	theme	cells	1134:1138	arg1	secretion					1100:1108	the enhanced paracrine secretion	1077:1108	the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold	1077:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	5	1	theme	typical	1359:1365	arg1	microenvironment					1375:1390	the typical uniform microenvironment	1355:1390	adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects	1272:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	5	2	theme	stem	1288:1291	arg1	cells					1293:1297	adipose-derived stem cells	1272:1297	adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects	1272:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	1	3	theme	promising	176:184	arg1	approach					186:193	a promising approach	174:193	a promising approach to accelerate tissue regeneration	174:227	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	4	4	theme	stiffness	1202:1210	arg1	scaffold					1212:1219	the gradient stiffness scaffold	1189:1219	the gradient stiffness scaffold	1189:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	0	5	theme	stem	86:89	arg1	cells					91:95	adipose-derived stem cells	70:95	adipose-derived stem cells	70:95	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	5	6	theme	printed	1237:1243	arg1	scaffolds					1254:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	7	theme	stem	701:704	arg1	cells					706:710	adipose-derived stem cells	685:710	adipose-derived stem cells	685:710	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	8	theme	therapeutic	759:769	arg1	purposes					771:778	therapeutic purposes	759:778	therapeutic purposes	759:778	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	9	theme	3D	385:386	arg1	hydrogel					417:424	a 3D bioprinting gelatin-alginate hydrogel	383:424	a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment	383:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	5	10	with	cells	1293:1297	arg1	architecture					1330:1341	a distinct yet successive architecture	1304:1341	a distinct yet successive architecture	1304:1341	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	5	11	theme	other	1464:1468	arg1	wounds					1478:1483	other chronic wounds	1464:1483	other chronic wounds	1464:1483	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	0	12	theme	full-thickness	101:114	arg1	regeneration					121:132	full-thickness skin regeneration	101:132	full-thickness skin regeneration	101:132	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	5	13	theme	distinct	1306:1313	arg1	architecture					1330:1341	a distinct yet successive architecture	1304:1341	a distinct yet successive architecture	1304:1341	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	14	theme	adipose-derived	685:699	arg1	cells					706:710	adipose-derived stem cells	685:710	adipose-derived stem cells	685:710	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	4	15	theme	paracrine	1090:1098	arg1	secretion					1100:1108	the enhanced paracrine secretion	1077:1108	the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold	1077:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	2	16	dep	substrates	618:627	arg1	encapsulated					717:728	encapsulated	717:728	were encapsulated in the present hydrogels for therapeutic purposes	712:778	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	5	17	theme	successive	1319:1328	arg1	architecture					1330:1341	a distinct yet successive architecture	1304:1341	a distinct yet successive architecture	1304:1341	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	18	theme	bioprinting	388:398	arg1	hydrogel					417:424	a 3D bioprinting gelatin-alginate hydrogel	383:424	a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment	383:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	4	19	theme	physical	1147:1154	arg1	microenvironment					1156:1171	the physical microenvironment	1143:1171	the physical microenvironment provided within the gradient stiffness scaffold	1143:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	1	20	theme	physical	297:304	arg1	microenvironment					306:321	the physical microenvironment	293:321	the physical microenvironment of tissues combined with therapeutic biological cues	293:374	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	5	21	link	adipose-derived	1272:1286	arg1	cells					1293:1297	adipose-derived stem cells	1272:1297	adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects	1272:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	22	theme	present	737:743	arg1	hydrogels					745:753	the present hydrogels	733:753	the present hydrogels for therapeutic purposes	733:778	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	0	23	theme	skin	116:119	arg1	regeneration					121:132	full-thickness skin regeneration	101:132	full-thickness skin regeneration	101:132	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	5	24	theme	adipose-derived	1272:1286	arg1	cells					1293:1297	adipose-derived stem cells	1272:1297	adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects	1272:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	4	25	theme	angiogenesis	968:979	arg1	efficiency					993:1002	the promoted angiogenesis and healing efficiency	955:1002	the promoted angiogenesis and healing efficiency	955:1002	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	2	26	theme	dermal	494:499	arg1	microenvironment					511:526	the dermal stiffness microenvironment	490:526	the dermal stiffness microenvironment	490:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	5	27	theme	skin	1406:1409	arg1	regeneration					1411:1422	skin regeneration	1406:1422	skin regeneration	1406:1422	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	28	theme	stiffness	501:509	arg1	microenvironment					511:526	the dermal stiffness microenvironment	490:526	the dermal stiffness microenvironment	490:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	29	theme	architecture	546:557	arg1	construction					559:570	architecture construction	546:570	architecture construction	546:570	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	4	30	theme	adipose-derived	1113:1127	arg1	cells					1134:1138	adipose-derived stem cells	1113:1138	adipose-derived stem cells	1113:1138	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	4	31	theme	enhanced	1081:1088	arg1	secretion					1100:1108	the enhanced paracrine secretion	1077:1108	the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold	1077:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	1	32	theme	tissue	209:214	arg1	regeneration					216:227	tissue regeneration	209:227	tissue regeneration	209:227	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	0	33	theme	3D	0:1	arg1	bioprinting					3:13	3D bioprinting	0:13	3D bioprinting of a gradient	0:27	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	4	34	theme	healing	985:991	arg1	efficiency					993:1002	the promoted angiogenesis and healing efficiency	955:1002	the promoted angiogenesis and healing efficiency	955:1002	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	5	35	theme	broader	1440:1446	arg1	applications					1448:1459	broader applications	1440:1459	broader applications	1440:1459	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	5	36	dep	accelerate	1395:1404	arg1	have					1435:1438	have	1435:1438	may have broader applications in other chronic wounds or tissue defects	1431:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	3	37	theme	adipose-derived	914:928	arg1	cells					935:939	the adipose-derived stem cells	910:939	the adipose-derived stem cells	910:939	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	5	38	theme	3D	1234:1235	arg1	scaffolds					1254:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	4	39	theme	gradient	1193:1200	arg1	scaffold					1212:1219	the gradient stiffness scaffold	1189:1219	the gradient stiffness scaffold	1189:1219	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	2	40	theme	gradient	640:647	arg1	cross-linking					659:671	gradient secondary cross-linking	640:671	gradient secondary cross-linking	640:671	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	40	theme	gradient	640:647	arg1	meanwhile					674:682	meanwhile	674:682	meanwhile	674:682	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	41	theme	calcium-containing	599:616	arg1	substrates					618:627	calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes	599:778	calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes	599:778	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	1	42	theme	tissues	326:332	arg1	microenvironment					306:321	the physical microenvironment	293:321	the physical microenvironment of tissues combined with therapeutic biological cues	293:374	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	5	43	theme	current	1226:1232	arg1	scaffolds					1254:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	44	theme	scaffolds	469:477	arg1	construction					434:445	the construction	430:445	the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment	430:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	5	45	theme	uniform	1367:1373	arg1	microenvironment					1375:1390	the typical uniform microenvironment	1355:1390	adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects	1272:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	3	46	theme	enhanced	870:877	arg1	proliferation					879:891	proliferation	879:891	proliferation	879:891	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	4	47	link	adipose-derived	1113:1127	arg1	cells					1134:1138	adipose-derived stem cells	1113:1138	adipose-derived stem cells	1113:1138	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	1	48	theme	great	234:238	arg1	challenges					240:249	great challenges	234:249	great challenges	234:249	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	2	49	theme	composite	459:467	arg1	scaffolds					469:477	gradient composite scaffolds	450:477	gradient composite scaffolds that mimic the dermal stiffness microenvironment	450:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	0	50	theme	gradient	20:27	arg1	bioprinting					3:13	3D bioprinting	0:13	3D bioprinting of a gradient	0:27	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	4	51	theme	stem	1129:1132	arg1	cells					1134:1138	adipose-derived stem cells	1113:1138	adipose-derived stem cells	1113:1138	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	5	52	theme	tissue	1488:1493	arg1	defects					1495:1501	tissue defects	1488:1501	tissue defects	1488:1501	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	53	theme	gradient	450:457	arg1	scaffolds					469:477	gradient composite scaffolds	450:477	gradient composite scaffolds that mimic the dermal stiffness microenvironment	450:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	1	54	theme	therapeutic	348:358	arg1	cues					371:374	therapeutic biological cues	348:374	therapeutic biological cues	348:374	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	4	55	theme	wound	1036:1040	arg1	model					1042:1046	the animal wound model	1025:1046	the animal wound model	1025:1046	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	5	56	theme	gradient	1245:1252	arg1	scaffolds					1254:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds	1222:1262	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	4	57	theme	promoted	959:966	arg1	efficiency					993:1002	the promoted angiogenesis and healing efficiency	955:1002	the promoted angiogenesis and healing efficiency	955:1002	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	0	58	theme	gelatin-alginate	39:54	arg1	hydrogel					56:63	gelatin-alginate hydrogel	39:63	gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration	39:132	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	1	59	theme	biological	360:369	arg1	cues					371:374	therapeutic biological cues	348:374	therapeutic biological cues	348:374	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	4	60	theme	animal	1029:1034	arg1	model					1042:1046	the animal wound model	1025:1046	the animal wound model	1025:1046	In addition, the promoted angiogenesis and healing efficiency was demonstrated via the animal wound model and was mainly attributed to the enhanced paracrine secretion of adipose-derived stem cells by the physical microenvironment provided within the gradient stiffness scaffold.					
36919715	2	61	from	bioink	589:594	arg1	substrates					618:627	calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes	599:778	calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes	599:778	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	0	62	link	adipose-derived	70:84	arg1	cells					91:95	adipose-derived stem cells	70:95	adipose-derived stem cells	70:95	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	1	63	theme	Current	135:141	arg1	scaffolds					158:166	Current hydrogel-based scaffolds	135:166	Current hydrogel-based scaffolds	135:166	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	2	64	link	adipose-derived	685:699	arg1	cells					706:710	adipose-derived stem cells	685:710	adipose-derived stem cells	685:710	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	3	65	theme	gradient-stiffness	785:802	arg1	scaffold					804:811	The gradient-stiffness scaffold	781:811	The gradient-stiffness scaffold	781:811	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	3	66	link	adipose-derived	914:928	arg1	cells					935:939	the adipose-derived stem cells	910:939	the adipose-derived stem cells	910:939	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	1	67	theme	hydrogel-based	143:156	arg1	scaffolds					158:166	Current hydrogel-based scaffolds	135:166	Current hydrogel-based scaffolds	135:166	Current hydrogel-based scaffolds offer a promising approach to accelerate tissue regeneration, but great challenges remain in developing platforms that mimic the physical microenvironment of tissues combined with therapeutic biological cues.					
36919715	5	68	theme	chronic	1470:1476	arg1	wounds					1478:1483	other chronic wounds	1464:1483	other chronic wounds	1464:1483	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	69	theme	secondary	649:657	arg1	cross-linking					659:671	gradient secondary cross-linking	640:671	gradient secondary cross-linking	640:671	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	2	69	theme	secondary	649:657	arg1	meanwhile					674:682	meanwhile	674:682	meanwhile	674:682	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	0	70	with	hydrogel	56:63	arg1	cells					91:95	adipose-derived stem cells	70:95	adipose-derived stem cells	70:95	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	0	71	theme	adipose-derived	70:84	arg1	cells					91:95	adipose-derived stem cells	70:95	adipose-derived stem cells	70:95	3D bioprinting of a gradient stiffened gelatin-alginate hydrogel with adipose-derived stem cells for full-thickness skin regeneration.					
36919715	3	72	theme	stem	930:933	arg1	cells					935:939	the adipose-derived stem cells	910:939	the adipose-derived stem cells	910:939	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	3	73	theme	good	823:826	arg1	stability					828:836	good stability	823:836	good stability	823:836	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	5	74	contain	have	1435:1438	arg1	which					1425:1429	which	1425:1429	which	1425:1429	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	5	74	contain	have	1435:1438	arg2	applications					1448:1459	broader applications	1440:1459	broader applications	1440:1459	The current 3D printed gradient scaffolds provide adipose-derived stem cells with a distinct yet successive architecture rather than the typical uniform microenvironment to accelerate skin regeneration, which may have broader applications in other chronic wounds or tissue defects.					
36919715	2	75	theme	gelatin-alginate	400:415	arg1	hydrogel					417:424	a 3D bioprinting gelatin-alginate hydrogel	383:424	a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment	383:526	Here, a 3D bioprinting gelatin-alginate hydrogel for the construction of gradient composite scaffolds that mimic the dermal stiffness microenvironment was developed for architecture construction by extruding the bioink on calcium-containing substrates to achieve gradient secondary cross-linking, meanwhile, adipose-derived stem cells were encapsulated in the present hydrogels for therapeutic purposes.					
36919715	3	76	theme	cells	935:939	arg1	proliferation					879:891	proliferation	879:891	proliferation	879:891	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	3	76	theme	cells	935:939	arg1	biocompatibility					842:857	biocompatibility	842:857	biocompatibility	842:857	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	3	76	theme	cells	935:939	arg1	stability					828:836	good stability	823:836	good stability	823:836	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
36919715	3	76	theme	cells	935:939	arg1	migration					897:905	migration	897:905	migration	897:905	The gradient-stiffness scaffold exhibited good stability and biocompatibility as well as enhanced proliferation and migration of the adipose-derived stem cells.					
37100314	0	0	theme	drug	107:110	arg1	delivery					112:119	curcumin drug delivery	98:119	curcumin drug delivery	98:119	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	1	1	with	cancers	183:189	arg1	effects					208:214	few adverse effects	196:214	few adverse effects	196:214	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	4	2	used	used	679:682	arg2	measurements					661:672	zeta potential measurements	646:672	zeta potential measurements	646:672	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
37100314	4	2	used	used	679:682	arg2	DLS					638:640	DLS	638:640	DLS	638:640	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
37100314	3	3	theme	bitter	546:551	arg1	oil					560:562	bitter almond oil	546:562	bitter almond oil	546:562	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	0	4	theme	curcumin	98:105	arg1	delivery					112:119	curcumin drug delivery	98:119	curcumin drug delivery	98:119	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	7	5	theme	In	1056:1057	arg1	experiments					1073:1083	In vitro release experiments	1056:1083	In vitro release experiments	1056:1083	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	3	6	theme	almond	553:558	arg1	oil					560:562	bitter almond oil	546:562	bitter almond oil	546:562	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	7	7	theme	increased	1214:1222	arg1	toxicity					1224:1231	the increased toxicity	1210:1231	the increased toxicity of the nanocomposites against MCF-7 cancer cells	1210:1280	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	8	8	located	detected	1339:1346	arg1	cells					1357:1361	MCF-7 cells	1351:1361	MCF-7 cells	1351:1361	Apoptosis was detected in MCF-7 cells via flow cytometry tests.					
37100314	8	8	located	detected	1339:1346	arg2	Apoptosis					1325:1333	Apoptosis	1325:1333	Apoptosis	1325:1333	Apoptosis was detected in MCF-7 cells via flow cytometry tests.					
37100314	9	9	theme	sustained	1514:1522	arg1	release					1550:1556	a sustained and pH-sensitive curcumin release	1512:1556	a sustained and pH-sensitive curcumin release	1512:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	7	10	theme	nanocarriers	1127:1138	arg1	release					1164:1170	the faster curcumin release	1144:1170	the faster curcumin release	1144:1170	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	7	10	theme	nanocarriers	1127:1138	arg1	pH-responsiveness					1102:1118	the pH-responsiveness	1098:1118	the pH-responsiveness of the nanocarriers	1098:1138	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	4	11	theme	curcumin-loaded	734:748	arg1	nanocarriers					750:761	curcumin-loaded nanocarriers	734:761	curcumin-loaded nanocarriers	734:761	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
37100314	9	12	theme	stable	1461:1466	arg1	systems					1500:1506	stable, uniform and effective delivery systems	1461:1506	stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release	1461:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	12	theme	stable	1461:1466	arg1	nanocarriers					1444:1455	the developed nanocarriers	1430:1455	the developed nanocarriers	1430:1455	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	5	13	theme	crystalline	797:807	arg1	interactions					783:794	The intermolecular interactions	764:794	The intermolecular interactions	764:794	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	5	13	theme	crystalline	797:807	arg1	structure					809:817	crystalline structure	797:817	crystalline structure	797:817	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	7	14	theme	cancer	1269:1274	arg1	cells					1276:1280	MCF-7 cancer cells	1263:1280	MCF-7 cancer cells	1263:1280	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	8	15	theme	cytometry	1372:1380	arg1	tests					1382:1386	flow cytometry tests	1367:1386	flow cytometry tests	1367:1386	Apoptosis was detected in MCF-7 cells via flow cytometry tests.					
37100314	1	16	theme	few	196:198	arg1	effects					208:214	few adverse effects	196:214	few adverse effects	196:214	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	7	17	dep	assay	1195:1199	arg1	pH.					1183:1185	pH.	1183:1185	pH.	1183:1185	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	3	18	contain	containing	535:544	arg1	nanoemulsion					522:533	A water/oil/water nanoemulsion	504:533	A water/oil/water nanoemulsion containing bitter almond oil	504:562	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	3	18	contain	containing	535:544	arg1	membrane					576:583	a membrane	574:583	a membrane surrounding the nanocarrier to control drug release	574:635	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	3	18	contain	containing	535:544	arg2	oil					560:562	bitter almond oil	546:562	bitter almond oil	546:562	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	7	19	theme	nanocomposites	1240:1253	arg1	toxicity					1224:1231	the increased toxicity	1210:1231	the increased toxicity of the nanocomposites against MCF-7 cancer cells	1210:1280	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	2	20	theme	graphene	306:313	arg1	RGO					322:324	RGO	322:324	RGO	322:324	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	20	theme	graphene	306:313	arg1	oxide					315:319	carboxymethyl cellulose (CMC)/starch/reduced graphene oxide	261:319	carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO)	261:325	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	1	21	theme	adverse	200:206	arg1	effects					208:214	few adverse effects	196:214	few adverse effects	196:214	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	5	22	theme	FTIR	876:879	arg1	spectroscopy					881:892	FTIR spectroscopy	876:892	FTIR spectroscopy	876:892	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	7	23	theme	free	1310:1313	arg1	curcumin					1315:1322	free curcumin	1310:1322	free curcumin	1310:1322	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	7	24	theme	MTT	1191:1193	arg1	assay					1195:1199	The MTT assay	1187:1199	The MTT assay	1187:1199	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	8	25	theme	MCF-7	1351:1355	arg1	cells					1357:1361	MCF-7 cells	1351:1361	MCF-7 cells	1351:1361	Apoptosis was detected in MCF-7 cells via flow cytometry tests.					
37100314	2	26	theme	double	400:405	arg1	nanoemulsions					407:419	double nanoemulsions	400:419	double nanoemulsions	400:419	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	0	27	theme	oxide	48:52	arg1	nanocarrier					82:92	a pH-sensitive nanocarrier	67:92	a pH-sensitive nanocarrier for curcumin drug delivery	67:119	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	0	27	theme	oxide	48:52	arg1	composite					54:62	graphene oxide composite	39:62	graphene oxide composite	39:62	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	0	28	theme	graphene	39:46	arg1	nanocarrier					82:92	a pH-sensitive nanocarrier	67:92	a pH-sensitive nanocarrier for curcumin drug delivery	67:119	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	0	28	theme	graphene	39:46	arg1	composite					54:62	graphene oxide composite	39:62	graphene oxide composite	39:62	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	9	29	theme	developed	1434:1442	arg1	nanocarriers					1444:1455	the developed nanocarriers	1430:1455	the developed nanocarriers	1430:1455	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	29	theme	developed	1434:1442	arg1	systems					1500:1506	stable, uniform and effective delivery systems	1461:1506	stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release	1461:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	2	30	theme	delivery	445:452	arg1	hydrogels					239:247	nanocomposite hydrogels	225:247	nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO)	225:325	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	30	theme	delivery	445:452	arg1	systems					454:460	pH-responsive delivery systems	431:460	pH-responsive delivery systems for curcumin, a potential antitumor drug	431:501	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	5	31	theme	nanocarriers	841:852	arg1	morphology					823:832	morphology	823:832	morphology	823:832	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	5	31	theme	nanocarriers	841:852	arg1	interactions					783:794	The intermolecular interactions	764:794	The intermolecular interactions	764:794	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	5	31	theme	nanocarriers	841:852	arg1	structure					809:817	crystalline structure	797:817	crystalline structure	797:817	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	2	32	theme	chemistry	356:364	arg1	approach					366:373	a green chemistry approach	348:373	a green chemistry approach	348:373	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	6	33	theme	drug	928:931	arg1	loading					933:939	The drug loading and entrapment efficiencies	924:967	loading	933:939	The drug loading and entrapment efficiencies were significantly improved compared to previously reported curcumin delivery systems.					
37100314	2	34	theme	pH-responsive	431:443	arg1	hydrogels					239:247	nanocomposite hydrogels	225:247	nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO)	225:325	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	34	theme	pH-responsive	431:443	arg1	systems					454:460	pH-responsive delivery systems	431:460	pH-responsive delivery systems for curcumin, a potential antitumor drug	431:501	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	9	35	theme	pH-sensitive	1528:1539	arg1	release					1550:1556	a sustained and pH-sensitive curcumin release	1512:1556	a sustained and pH-sensitive curcumin release	1512:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	6	36	theme	delivery	1038:1045	arg1	systems					1047:1053	previously reported curcumin delivery systems	1009:1053	previously reported curcumin delivery systems	1009:1053	The drug loading and entrapment efficiencies were significantly improved compared to previously reported curcumin delivery systems.					
37100314	5	37	theme	intermolecular	768:781	arg1	morphology					823:832	morphology	823:832	morphology	823:832	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	5	37	theme	intermolecular	768:781	arg1	interactions					783:794	The intermolecular interactions	764:794	The intermolecular interactions	764:794	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	5	37	theme	intermolecular	768:781	arg1	structure					809:817	crystalline structure	797:817	crystalline structure	797:817	The intermolecular interactions, crystalline structure and morphology of the nanocarriers were analyzed through FTIR spectroscopy, XRD and FESEM, respectively.					
37100314	8	38	theme	flow	1367:1370	arg1	tests					1382:1386	flow cytometry tests	1367:1386	flow cytometry tests	1367:1386	Apoptosis was detected in MCF-7 cells via flow cytometry tests.					
37100314	7	39	theme	MCF-7	1263:1267	arg1	cells					1276:1280	MCF-7 cancer cells	1263:1280	MCF-7 cancer cells	1263:1280	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	0	40	theme	pH-sensitive	69:80	arg1	nanocarrier					82:92	a pH-sensitive nanocarrier	67:92	a pH-sensitive nanocarrier for curcumin drug delivery	67:119	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	0	40	theme	pH-sensitive	69:80	arg1	composite					54:62	graphene oxide composite	39:62	graphene oxide composite	39:62	Carboxymethyl cellulose/starch/reduced graphene oxide composite as a pH-sensitive nanocarrier for curcumin drug delivery.					
37100314	6	41	theme	curcumin	1029:1036	arg1	systems					1047:1053	previously reported curcumin delivery systems	1009:1053	previously reported curcumin delivery systems	1009:1053	The drug loading and entrapment efficiencies were significantly improved compared to previously reported curcumin delivery systems.					
37100314	7	42	theme	faster	1148:1153	arg1	release					1164:1170	the faster curcumin release	1144:1170	the faster curcumin release	1144:1170	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	3	43	theme	drug	624:627	arg1	release					629:635	drug release	624:635	drug release	624:635	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	6	44	theme	entrapment	945:954	arg1	efficiencies					956:967	The drug loading and entrapment efficiencies	924:967	efficiencies	956:967	The drug loading and entrapment efficiencies were significantly improved compared to previously reported curcumin delivery systems.					
37100314	1	45	theme	promising	141:149	arg1	carriers					156:163	promising drug carriers	141:163	promising drug carriers	141:163	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	1	45	theme	promising	141:149	arg1	Nanocomposites					122:135	Nanocomposites	122:135	Nanocomposites	122:135	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	2	46	theme	potential	478:486	arg1	drug					498:501	a potential antitumor drug	476:501	a potential antitumor drug	476:501	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	46	theme	potential	478:486	arg1	curcumin					466:473	curcumin	466:473	curcumin	466:473	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	6	47	theme	reported	1020:1027	arg1	systems					1047:1053	previously reported curcumin delivery systems	1009:1053	previously reported curcumin delivery systems	1009:1053	The drug loading and entrapment efficiencies were significantly improved compared to previously reported curcumin delivery systems.					
37100314	7	48	theme	curcumin	1155:1162	arg1	release					1164:1170	the faster curcumin release	1144:1170	the faster curcumin release	1144:1170	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	1	49	theme	drug	151:154	arg1	carriers					156:163	promising drug carriers	141:163	promising drug carriers	141:163	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	1	49	theme	drug	151:154	arg1	Nanocomposites					122:135	Nanocomposites	122:135	Nanocomposites	122:135	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	9	50	theme	uniform	1469:1475	arg1	systems					1500:1506	stable, uniform and effective delivery systems	1461:1506	stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release	1461:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	50	theme	uniform	1469:1475	arg1	nanocarriers					1444:1455	the developed nanocarriers	1430:1455	the developed nanocarriers	1430:1455	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	2	51	theme	nanocomposite	225:237	arg1	systems					454:460	pH-responsive delivery systems	431:460	pH-responsive delivery systems for curcumin, a potential antitumor drug	431:501	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	51	theme	nanocomposite	225:237	arg1	hydrogels					239:247	nanocomposite hydrogels	225:247	nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO)	225:325	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	52	theme	/starch/reduced	290:304	arg1	RGO					322:324	RGO	322:324	RGO	322:324	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	52	theme	/starch/reduced	290:304	arg1	oxide					315:319	carboxymethyl cellulose (CMC)/starch/reduced graphene oxide	261:319	carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO)	261:325	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	53	theme	green	350:354	arg1	approach					366:373	a green chemistry approach	348:373	a green chemistry approach	348:373	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	4	54	theme	zeta	646:649	arg1	measurements					661:672	zeta potential measurements	646:672	zeta potential measurements	646:672	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
37100314	3	55	theme	water/oil/water	506:520	arg1	nanoemulsion					522:533	A water/oil/water nanoemulsion	504:533	A water/oil/water nanoemulsion containing bitter almond oil	504:562	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	3	55	theme	water/oil/water	506:520	arg1	membrane					576:583	a membrane	574:583	a membrane surrounding the nanocarrier to control drug release	574:635	A water/oil/water nanoemulsion containing bitter almond oil served as a membrane surrounding the nanocarrier to control drug release.					
37100314	7	56	dep	In	1056:1057	arg1	vitro					1059:1063	vitro	1059:1063	vitro	1059:1063	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	9	57	theme	effective	1481:1489	arg1	systems					1500:1506	stable, uniform and effective delivery systems	1461:1506	stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release	1461:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	57	theme	effective	1481:1489	arg1	nanocarriers					1444:1455	the developed nanocarriers	1430:1455	the developed nanocarriers	1430:1455	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	58	theme	curcumin	1541:1548	arg1	release					1550:1556	a sustained and pH-sensitive curcumin release	1512:1556	a sustained and pH-sensitive curcumin release	1512:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	59	theme	delivery	1491:1498	arg1	systems					1500:1506	stable, uniform and effective delivery systems	1461:1506	stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release	1461:1556	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	9	59	theme	delivery	1491:1498	arg1	nanocarriers					1444:1455	the developed nanocarriers	1430:1455	the developed nanocarriers	1430:1455	The results obtained herein support that the developed nanocarriers are stable, uniform and effective delivery systems for a sustained and pH-sensitive curcumin release.					
37100314	2	60	theme	antitumor	488:496	arg1	drug					498:501	a potential antitumor drug	476:501	a potential antitumor drug	476:501	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	2	60	theme	antitumor	488:496	arg1	curcumin					466:473	curcumin	466:473	curcumin	466:473	Herein, nanocomposite hydrogels composed of carboxymethyl cellulose (CMC)/starch/reduced graphene oxide (RGO) were synthesized via a green chemistry approach and then encapsulated in double nanoemulsions to act as pH-responsive delivery systems for curcumin, a potential antitumor drug.					
37100314	4	61	theme	potential	651:659	arg1	measurements					661:672	zeta potential measurements	646:672	zeta potential measurements	646:672	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
37100314	7	62	theme	release	1065:1071	arg1	experiments					1073:1083	In vitro release experiments	1056:1083	In vitro release experiments	1056:1083	In vitro release experiments demonstrated the pH-responsiveness of the nanocarriers and the faster curcumin release at a lower pH. The MTT assay revealed the increased toxicity of the nanocomposites against MCF-7 cancer cells compared to CMC, CMC/RGO or free curcumin.					
37100314	1	63	theme	terminal	174:181	arg1	cancers					183:189	terminal cancers	174:189	terminal cancers with few adverse effects	174:214	Nanocomposites are promising drug carriers to treat terminal cancers with few adverse effects.					
37100314	4	64	theme	nanocarriers	750:761	arg1	stability					721:729	the stability	717:729	the stability of curcumin-loaded nanocarriers	717:761	DLS and zeta potential measurements were used to estimate the size and confirm the stability of curcumin-loaded nanocarriers.					
35532355	11	0	theme	12	2086:2087	arg1	I					2078:2078	Salmonella enterica serovar I 4,[5]	2050:2084	I	2078:2078	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	3	1	theme	short	770:774	arg1	SCFA					794:797	SCFA	794:797	SCFA	794:797	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	1	theme	short	770:774	arg1	acid					788:791	cecal short chain fatty acid	764:791	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	12	2	theme	inoculated	2268:2277	arg1	pigs					2279:2282	Salmonella inoculated pigs	2257:2282	Salmonella inoculated pigs	2257:2282	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	10	3	from	bacteria	2001:2008	arg1	intestines					2038:2047	the intestines	2034:2047	the intestines	2034:2047	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	5	4	theme	Salmonella	1192:1201	arg1	amount					1182:1187	and the amount	1174:1187	amount	1182:1187	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	4	theme	Salmonella	1192:1201	arg1	Salmonella					1192:1201	Salmonella	1192:1201	Salmonella	1192:1201	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	1	5	theme	enterica	193:200	arg1	I					210:210	Salmonella enterica serovar I 4,[5]	182:216	I	210:210	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	9	6	theme	S.	1777:1778	arg1	I					1797:1797	S. enterica serovar I 4,[5]	1777:1803	I	1797:1797	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	7	7	theme	feeding	1551:1557	arg1	interactions					1559:1570	bacterial cross feeding interactions	1535:1570	bacterial cross feeding interactions that result in the production of certain SCFAs	1535:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	2	8	theme	standard	600:607	arg1	diet					617:620	a standard control diet	598:620	a standard control diet over 21 days	598:633	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	1	9	dep	multidrug-resistant	286:304	arg1	resistant					307:315	resistant	307:315	resistant	307:315	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	1	9	dep	multidrug-resistant	286:304	arg1	tolerant					356:363	tolerant	356:363	tolerant	356:363	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	6	10	theme	cecal	1304:1308	arg1	concentrations					1310:1323	cecal concentrations	1304:1323	cecal concentrations of butyrate, valerate, caproate	1304:1355	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	10	11	theme	food	1964:1967	arg1	types					1955:1959	types	1955:1959	types of food that help to support beneficial bacteria and their activities in the intestines	1955:2047	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	11	theme	food	1964:1967	arg1	Prebiotics					1900:1909	IMPORTANCE Prebiotics	1889:1909	IMPORTANCE Prebiotics	1889:1909	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	11	theme	food	1964:1967	arg1	starch					1937:1942	resistant potato starch	1920:1942	resistant potato starch (RPS)	1920:1948	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	7	12	theme	bacterial	1535:1543	arg1	interactions					1559:1570	bacterial cross feeding interactions	1535:1570	bacterial cross feeding interactions that result in the production of certain SCFAs	1535:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	7	13	from	reduction	1461:1469	arg1	shedding					1485:1492	Salmonella shedding	1474:1492	Salmonella shedding	1474:1492	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	9	14	from	present	1869:1875	arg1	gut					1884:1886	the gut	1880:1886	the gut	1880:1886	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	3	15	theme	control	821:827	arg1	animals					829:835	control animals	821:835	control animals	821:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	2	16	theme	corn	547:550	arg1	starch					552:557	high amylose corn starch	534:557	high amylose corn starch	534:557	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	12	17	contain	containing	2305:2314	arg2	RPS					2316:2318	RPS	2316:2318	RPS	2316:2318	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	12	17	contain	containing	2305:2314	arg1	diet					2300:2303	a diet	2298:2303	a diet containing RPS	2298:2318	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	9	18	theme	bacterial	1843:1851	arg1	communities					1853:1863	appropriate bacterial communities	1831:1863	appropriate bacterial communities	1831:1863	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	5	19	theme	amount	1182:1187	arg1	abundances					1160:1169	their abundances	1154:1169	their abundances of and the amount of Salmonella in the feces of their hosts	1154:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	14	20	theme	serovar	2849:2855	arg1	I					2857:2857	Salmonella serovar I 4,[5]	2838:2863	I	2857:2857	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	6	21	theme	significant	1265:1275	arg1	associations					1286:1297	significant positive associations	1265:1297	significant positive associations	1265:1297	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	9	22	theme	enterica	1780:1787	arg1	I					1797:1797	S. enterica serovar I 4,[5]	1777:1803	I	1797:1797	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	3	23	theme	relative	809:816	arg1	profiles					800:807	different cecal short chain fatty acid (SCFA) profiles	754:807	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	1	24	theme	≥3	320:321	arg1	classes					337:343	≥3 antimicrobial classes	320:343	≥3 antimicrobial classes	320:343	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	11	25	theme	Salmonella	2050:2059	arg1	I					2078:2078	Salmonella enterica serovar I 4,[5]	2050:2084	I	2078:2078	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	8	26	theme	acid	1654:1657	arg1	mix					1659:1661	a fatty acid mix	1646:1661	a fatty acid mix	1646:1661	However, directly feeding a fatty acid mix did not replicate the effect.					
35532355	10	27	from	activities	2020:2029	arg1	intestines					2038:2047	the intestines	2034:2047	the intestines	2034:2047	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	2	28	theme	Salmonella	458:467	arg1	I					469:469	Salmonella I 4,[5]	458:475	I	469:469	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	4	29	theme	butyrate	952:959	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	14	30	theme	Salmonella	2838:2847	arg1	I					2857:2857	Salmonella serovar I 4,[5]	2838:2863	I	2857:2857	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	31	theme	pigs	2766:2769	arg1	feces					2757:2761	the feces	2753:2761	the feces of pigs	2753:2769	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	9	32	theme	serovar	1789:1795	arg1	I					1797:1797	S. enterica serovar I 4,[5]	1777:1803	I	1797:1797	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	1	33	dep	I	210:210	arg1	pathogen					240:247	a foodborne pathogen	228:247	a foodborne pathogen of concern	228:258	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	1	33	dep	I	210:210	arg1	i					221:221	i	221:221	i	221:221	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	4	34	theme	valerate	962:969	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	2	35	from	shedding	484:491	arg1	swine					496:500	swine	496:500	swine	496:500	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	2	36	theme	potato	513:518	arg1	RPS					528:530	RPS	528:530	RPS	528:530	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	2	36	theme	potato	513:518	arg1	starch					520:525	resistant potato starch	503:525	resistant potato starch (RPS)	503:531	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	7	37	theme	Salmonella	1474:1483	arg1	shedding					1485:1492	Salmonella shedding	1474:1492	Salmonella shedding	1474:1492	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	10	38	theme	potato	1930:1935	arg1	RPS					1945:1947	RPS	1945:1947	RPS	1945:1947	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	38	theme	potato	1930:1935	arg1	starch					1937:1942	resistant potato starch	1920:1942	resistant potato starch (RPS)	1920:1948	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	4	39	theme	greater	920:926	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	0	40	theme	Salmonella	67:76	arg1	I					95:95	Reduced Salmonella enterica serovar I 4,[5]	59:101	I	95:95	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	0	41	theme	Potato	167:172	arg1	Starch					174:179	Resistant Potato Starch	157:179	Resistant Potato Starch	157:179	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	5	42	theme	several	1031:1037	arg1	taxa					1049:1052	several bacterial taxa	1031:1052	several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others)	1031:1111	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	42	theme	several	1031:1037	arg1	Olsenella					1069:1077	Olsenella	1069:1077	Olsenella	1069:1077	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	42	theme	several	1031:1037	arg1	Bifidobacterium					1084:1098	Bifidobacterium	1084:1098	Bifidobacterium	1084:1098	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	42	theme	several	1031:1037	arg1	Prevotella_7					1055:1066	Prevotella_7	1055:1066	Prevotella_7	1055:1066	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	0	43	theme	serovar	87:93	arg1	I					95:95	Reduced Salmonella enterica serovar I 4,[5]	59:101	I	95:95	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	1	44	theme	foodborne	230:238	arg1	pathogen					240:247	a foodborne pathogen	228:247	a foodborne pathogen of concern	228:258	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	3	45	theme	fecal	690:694	arg1	shedding					696:703	Salmonella fecal shedding	679:703	Salmonella fecal shedding	679:703	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	13	46	theme	Salmonella	2563:2572	arg1	I					2574:2574	Salmonella I 4,[5]	2563:2580	I	2574:2574	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	2	47	theme	in-feed	387:393	arg1	additives					395:403	three in-feed additives	381:403	three in-feed additives	381:403	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	10	48	theme	IMPORTANCE	1889:1898	arg1	types					1955:1959	types	1955:1959	types of food that help to support beneficial bacteria and their activities in the intestines	1955:2047	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	48	theme	IMPORTANCE	1889:1898	arg1	Prebiotics					1900:1909	IMPORTANCE Prebiotics	1889:1909	IMPORTANCE Prebiotics	1889:1909	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	48	theme	IMPORTANCE	1889:1898	arg1	starch					1937:1942	resistant potato starch	1920:1942	resistant potato starch (RPS)	1920:1948	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	3	49	theme	cecal	764:768	arg1	SCFA					794:797	SCFA	794:797	SCFA	794:797	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	49	theme	cecal	764:768	arg1	acid					788:791	cecal short chain fatty acid	764:791	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	14	50	from	amount	2729:2734	arg1	feces					2757:2761	the feces	2753:2761	the feces of pigs	2753:2769	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	11	51	theme	foodborne	2098:2106	arg1	pathogen					2108:2115	a foodborne pathogen	2096:2115	a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed	2096:2233	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	5	52	theme	hosts	1225:1229	arg1	feces					1210:1214	the feces	1206:1214	the feces of their hosts	1206:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	4	53	theme	caproate	972:979	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	0	54	theme	Short	0:4	arg1	Acids					18:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	14	55	theme	gut	2696:2698	arg1	microorganisms					2700:2713	certain gut microorganisms	2688:2713	certain gut microorganisms	2688:2713	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	0	56	dep	Salmonella	67:76	arg1	enterica					78:85	enterica	78:85	enterica	78:85	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	3	57	theme	bacterial	716:724	arg1	compositions					736:747	different bacterial community compositions	706:747	different bacterial community compositions	706:747	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	5	58	dep	taxa	1049:1052	arg1	taxa					1049:1052	several bacterial taxa	1031:1052	several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others)	1031:1111	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	58	dep	taxa	1049:1052	arg1	Prevotella_7					1055:1066	Prevotella_7	1055:1066	Prevotella_7	1055:1066	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	58	dep	taxa	1049:1052	arg1	Olsenella					1069:1077	Olsenella	1069:1077	Olsenella	1069:1077	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	58	dep	taxa	1049:1052	arg1	Bifidobacterium					1084:1098	Bifidobacterium	1084:1098	Bifidobacterium	1084:1098	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	58	dep	taxa	1049:1052	arg1	others					1105:1110	others	1105:1110	others	1105:1110	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	0	59	theme	Fatty	12:16	arg1	Acids					18:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	14	60	dep	MDR	2834:2836	arg1	12					2865:2866	12	2865:2866	12	2865:2866	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	60	dep	MDR	2834:2836	arg1	I					2857:2857	Salmonella serovar I 4,[5]	2838:2863	I	2857:2857	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	60	dep	MDR	2834:2836	arg1	i					2868:2868	i	2868:2868	i	2868:2868	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	61	dep	likely	2627:2632	arg1	reduce					2785:2790	reduce	2785:2790	reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-	2785:2870	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	61	dep	likely	2627:2632	arg1	reduce					2718:2723	reduce	2718:2723	reduce the amount of Salmonella in the feces of pigs	2718:2769	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	12	62	theme	beneficial	2369:2378	arg1	bacteria					2380:2387	certain beneficial bacteria	2361:2387	certain beneficial bacteria	2361:2387	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	13	63	with	swine	2488:2492	arg1	abundance					2506:2514	higher abundance	2499:2514	higher abundance of these types of beneficial bacteria	2499:2552	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	14	64	with	ill	2825:2827	arg1	MDR					2834:2836	MDR	2834:2836	MDR Salmonella serovar I 4,[5],12:i:-	2834:2870	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	12	65	dep	colonization	2332:2343	arg1	the					2328:2330	the	2328:2330	the	2328:2330	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	4	66	contain	have	915:918	arg1	pigs					870:873	pigs	870:873	pigs shedding the least Salmonella	870:903	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	4	66	contain	have	915:918	arg2	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	4	67	theme	treatment	853:861	arg1	group					863:867	the RPS treatment group	845:867	the RPS treatment group	845:867	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	11	68	dep	sick	2202:2205	arg1	humans					2195:2200	humans	2195:2200	humans	2195:2200	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	3	69	theme	chain	776:780	arg1	SCFA					794:797	SCFA	794:797	SCFA	794:797	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	69	theme	chain	776:780	arg1	acid					788:791	cecal short chain fatty acid	764:791	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	2	70	theme	high	534:537	arg1	starch					552:557	high amylose corn starch	534:557	high amylose corn starch	534:557	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	9	71	dep	multidrug-resistant	1751:1769	arg1	I					1797:1797	S. enterica serovar I 4,[5]	1777:1803	I	1797:1797	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	71	dep	multidrug-resistant	1751:1769	arg1	swine					1815:1819	swine	1815:1819	swine	1815:1819	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	13	72	theme	fed	2479:2481	arg1	RPS					2483:2485	those fed RPS	2473:2485	those fed RPS	2473:2485	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	7	73	dep	suggest	1434:1440	arg1	dependent					1501:1509	dependent	1501:1509	dependent	1501:1509	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	7	74	theme	interactions	1559:1570	arg1	establishment					1518:1530	the establishment	1514:1530	the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs	1514:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	5	75	from	feces	1210:1214	arg1	abundances					1160:1169	their abundances	1154:1169	their abundances of and the amount of Salmonella in the feces of their hosts	1154:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	9	76	theme	effective	1725:1733	arg1	means					1735:1739	an effective means	1722:1739	an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut	1722:1886	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	76	theme	effective	1725:1733	arg1	supplementation					1697:1711	RPS supplementation	1693:1711	RPS supplementation	1693:1711	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	77	from	gut	1884:1886	arg1	present					1869:1875	present	1869:1875	present	1869:1875	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	14	78	theme	prebiotic	2654:2662	arg1	RPS					2664:2666	the prebiotic RPS	2650:2666	the prebiotic RPS	2650:2666	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	1	79	theme	Salmonella	182:191	arg1	I					210:210	Salmonella enterica serovar I 4,[5]	182:216	I	210:210	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	7	80	theme	cross	1545:1549	arg1	interactions					1559:1570	bacterial cross feeding interactions	1535:1570	bacterial cross feeding interactions that result in the production of certain SCFAs	1535:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	10	81	theme	resistant	1920:1928	arg1	RPS					1945:1947	RPS	1945:1947	RPS	1945:1947	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	10	81	theme	resistant	1920:1928	arg1	starch					1937:1942	resistant potato starch	1920:1942	resistant potato starch (RPS)	1920:1948	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	2	82	theme	control	609:615	arg1	diet					617:620	a standard control diet	598:620	a standard control diet over 21 days	598:633	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	1	83	theme	antimicrobial	323:335	arg1	classes					337:343	≥3 antimicrobial classes	320:343	≥3 antimicrobial classes	320:343	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	1	84	theme	serovar	202:208	arg1	I					210:210	Salmonella enterica serovar I 4,[5]	182:216	I	210:210	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	3	85	theme	different	754:762	arg1	profiles					800:807	different cecal short chain fatty acid (SCFA) profiles	754:807	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	86	theme	acid	788:791	arg1	profiles					800:807	different cecal short chain fatty acid (SCFA) profiles	754:807	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	87	from	reduction	666:674	arg1	compositions					736:747	different bacterial community compositions	706:747	different bacterial community compositions	706:747	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	87	from	reduction	666:674	arg1	shedding					696:703	Salmonella fecal shedding	679:703	Salmonella fecal shedding	679:703	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	87	from	reduction	666:674	arg1	profiles					800:807	different cecal short chain fatty acid (SCFA) profiles	754:807	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	9	88	theme	appropriate	1831:1841	arg1	communities					1853:1863	appropriate bacterial communities	1831:1863	appropriate bacterial communities	1831:1863	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	8	89	theme	fatty	1648:1652	arg1	mix					1659:1661	a fatty acid mix	1646:1661	a fatty acid mix	1646:1661	However, directly feeding a fatty acid mix did not replicate the effect.					
35532355	6	90	theme	positive	1277:1284	arg1	associations					1286:1297	significant positive associations	1265:1297	significant positive associations	1265:1297	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	2	91	theme	fatty	566:570	arg1	blend					577:581	a fatty acid blend	564:581	a fatty acid blend	564:581	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	1	92	theme	many	268:271	arg1	isolates					273:280	many isolates	268:280	many isolates	268:280	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	6	93	theme	taxa	1251:1254	arg1	taxa					1251:1254	these same taxa	1240:1254	these same taxa	1240:1254	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	6	93	theme	taxa	1251:1254	arg1	Many					1232:1235	Many	1232:1235	Many	1232:1235	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	9	94	theme	RPS	1693:1695	arg1	means					1735:1739	an effective means	1722:1739	an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut	1722:1886	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	94	theme	RPS	1693:1695	arg1	supplementation					1697:1711	RPS supplementation	1693:1711	RPS supplementation	1693:1711	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	12	95	theme	Salmonella	2257:2266	arg1	pigs					2279:2282	Salmonella inoculated pigs	2257:2282	Salmonella inoculated pigs	2257:2282	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	11	96	theme	pigs	2160:2163	arg1	intestines					2146:2155	the intestines	2142:2155	the intestines of pigs without disease	2142:2179	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	13	97	theme	higher	2499:2504	arg1	abundance					2506:2514	higher abundance	2499:2514	higher abundance of these types of beneficial bacteria	2499:2552	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	9	98	attach	present	1869:1875	arg1	gut					1884:1886	the gut	1880:1886	the gut	1880:1886	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	98	attach	present	1869:1875	arg2	communities					1853:1863	appropriate bacterial communities	1831:1863	appropriate bacterial communities	1831:1863	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	11	99	theme	serovar	2070:2076	arg1	I					2078:2078	Salmonella enterica serovar I 4,[5]	2050:2084	I	2078:2078	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	5	100	theme	bacterial	1039:1047	arg1	taxa					1049:1052	several bacterial taxa	1031:1052	several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others)	1031:1111	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	100	theme	bacterial	1039:1047	arg1	Olsenella					1069:1077	Olsenella	1069:1077	Olsenella	1069:1077	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	100	theme	bacterial	1039:1047	arg1	Bifidobacterium					1084:1098	Bifidobacterium	1084:1098	Bifidobacterium	1084:1098	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	5	100	theme	bacterial	1039:1047	arg1	Prevotella_7					1055:1066	Prevotella_7	1055:1066	Prevotella_7	1055:1066	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	3	101	theme	RPS-fed	641:647	arg1	pigs					649:652	Only RPS-fed pigs	636:652	Only RPS-fed pigs	636:652	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	10	102	theme	beneficial	1990:1999	arg1	bacteria					2001:2008	beneficial bacteria	1990:2008	beneficial bacteria	1990:2008	IMPORTANCE Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines.					
35532355	0	103	from	I	95:95	arg1	Swine					122:126	Swine	122:126	Swine	122:126	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	4	104	theme	cecal	928:932	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	2	105	theme	acid	572:575	arg1	blend					577:581	a fatty acid blend	564:581	a fatty acid blend	564:581	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	0	106	theme	Reduced	59:65	arg1	I					95:95	Reduced Salmonella enterica serovar I 4,[5]	59:101	I	95:95	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	6	107	theme	butyrate	1328:1335	arg1	concentrations					1310:1323	cecal concentrations	1304:1323	cecal concentrations of butyrate, valerate, caproate	1304:1355	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	9	108	dep	I	1797:1797	arg1	i					1808:1808	i	1808:1808	i	1808:1808	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	5	109	theme	RPS-fed	1017:1023	arg1	pigs					1025:1028	RPS-fed pigs	1017:1028	RPS-fed pigs	1017:1028	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	14	110	theme	Salmonella	2739:2748	arg1	Salmonella					2739:2748	Salmonella	2739:2748	Salmonella	2739:2748	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	110	theme	Salmonella	2739:2748	arg1	amount					2729:2734	the amount	2725:2734	the amount of Salmonella in the feces of pigs	2725:2769	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	2	111	theme	amylose	539:545	arg1	starch					552:557	high amylose corn starch	534:557	high amylose corn starch	534:557	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	13	112	theme	bacteria	2545:2552	arg1	types					2525:2529	these types	2519:2529	these types of beneficial bacteria	2519:2552	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	0	113	theme	Resistant	157:165	arg1	Starch					174:179	Resistant Potato Starch	157:179	Resistant Potato Starch	157:179	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	7	114	theme	RPS-associated	1446:1459	arg1	reduction					1461:1469	the RPS-associated reduction	1442:1469	the RPS-associated reduction in Salmonella shedding	1442:1492	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	11	115	dep	I	2078:2078	arg1	i					2089:2089	i	2089:2089	i	2089:2089	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	11	115	dep	I	2078:2078	arg1	pathogen					2108:2115	a foodborne pathogen	2096:2115	a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed	2096:2233	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	2	116	theme	resistant	503:511	arg1	RPS					528:530	RPS	528:530	RPS	528:530	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	2	116	theme	resistant	503:511	arg1	starch					520:525	resistant potato starch	503:525	resistant potato starch (RPS)	503:531	In this study, three in-feed additives were individually tested for their ability to reduce Salmonella I 4,[5],12:i:- shedding in swine: resistant potato starch (RPS), high amylose corn starch, and a fatty acid blend, compared with a standard control diet over 21 days.					
35532355	12	117	theme	Salmonella	2425:2434	arg1	Salmonella					2425:2434	Salmonella	2425:2434	Salmonella	2425:2434	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	12	117	theme	Salmonella	2425:2434	arg1	amount					2415:2420	the amount	2411:2420	the amount of Salmonella	2411:2434	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	0	118	theme	Chain	6:10	arg1	Acids					18:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids	0:22	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	1	119	theme	concern	252:258	arg1	pathogen					240:247	a foodborne pathogen	228:247	a foodborne pathogen of concern	228:258	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	6	120	contain	had	1261:1263	arg2	associations					1286:1297	significant positive associations	1265:1297	significant positive associations	1265:1297	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	6	120	contain	had	1261:1263	arg1	taxa					1251:1254	these same taxa	1240:1254	these same taxa	1240:1254	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	6	120	contain	had	1261:1263	arg1	Many					1232:1235	Many	1232:1235	Many	1232:1235	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	14	121	theme	microorganisms	2700:2713	arg1	RPS					2664:2666	the prebiotic RPS	2650:2666	the prebiotic RPS	2650:2666	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	14	121	theme	microorganisms	2700:2713	arg1	presence					2676:2683	the presence	2672:2683	the presence of certain gut microorganisms	2672:2713	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	3	122	theme	Salmonella	679:688	arg1	shedding					696:703	Salmonella fecal shedding	679:703	Salmonella fecal shedding	679:703	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	4	123	theme	succinate	986:994	arg1	concentrations					934:947	greater cecal concentrations	920:947	greater cecal concentrations of butyrate, valerate, caproate, and succinate	920:994	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	14	124	theme	certain	2688:2694	arg1	microorganisms					2700:2713	certain gut microorganisms	2688:2713	certain gut microorganisms	2688:2713	This work illustrates likely synergy between the prebiotic RPS and the presence of certain gut microorganisms to reduce the amount of Salmonella in the feces of pigs and therefore reduce the risk that humans will become ill with MDR Salmonella serovar I 4,[5],12:i:-.					
35532355	3	125	theme	community	726:734	arg1	compositions					736:747	different bacterial community compositions	706:747	different bacterial community compositions	706:747	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	5	126	from	abundances	1160:1169	arg1	feces					1210:1214	the feces	1206:1214	the feces of their hosts	1206:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	0	127	theme	Bacterial	28:36	arg1	Taxa					38:41	Bacterial Taxa	28:41	Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine	28:126	Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch.					
35532355	13	128	theme	types	2525:2529	arg1	abundance					2506:2514	higher abundance	2499:2514	higher abundance of these types of beneficial bacteria	2499:2552	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	3	129	theme	different	706:714	arg1	compositions					736:747	different bacterial community compositions	706:747	different bacterial community compositions	706:747	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	12	130	theme	certain	2361:2367	arg1	bacteria					2380:2387	certain beneficial bacteria	2361:2387	certain beneficial bacteria	2361:2387	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	1	131	theme	12	218:219	arg1	I					210:210	Salmonella enterica serovar I 4,[5]	182:216	I	210:210	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen of concern because many isolates are multidrug-resistant (resistant to ≥3 antimicrobial classes) and metal tolerant.					
35532355	13	132	theme	beneficial	2534:2543	arg1	bacteria					2545:2552	beneficial bacteria	2534:2552	beneficial bacteria	2534:2552	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	7	133	theme	certain	1605:1611	arg1	SCFAs					1613:1617	certain SCFAs	1605:1617	certain SCFAs	1605:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	5	134	from	amount	1182:1187	arg1	feces					1210:1214	the feces	1206:1214	the feces of their hosts	1206:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35532355	12	135	theme	bacteria	2380:2387	arg1	activity					2349:2356	activity	2349:2356	activity	2349:2356	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	12	135	theme	bacteria	2380:2387	arg1	colonization					2332:2343	colonization	2332:2343	colonization	2332:2343	Here we show that in Salmonella inoculated pigs, feeding them a diet containing RPS altered the colonization and activity of certain beneficial bacteria in a way that reduced the amount of Salmonella in their feces.					
35532355	13	136	dep	less	2558:2561	arg1	12					2582:2583	12	2582:2583	12	2582:2583	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	13	136	dep	less	2558:2561	arg1	i					2585:2585	i	2585:2585	i	2585:2585	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	13	136	dep	less	2558:2561	arg1	feces					2598:2602	their feces	2592:2602	their feces	2592:2602	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	13	136	dep	less	2558:2561	arg1	I					2574:2574	Salmonella I 4,[5]	2563:2580	I	2574:2574	Additionally, within those fed RPS, swine with higher abundance of these types of beneficial bacteria had less Salmonella I 4,[5],12:i:- in their feces.					
35532355	9	137	located	present	1869:1875	arg1	gut					1884:1886	the gut	1880:1886	the gut	1880:1886	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	9	137	located	present	1869:1875	arg2	communities					1853:1863	appropriate bacterial communities	1831:1863	appropriate bacterial communities	1831:1863	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	6	138	theme	same	1246:1249	arg1	taxa					1251:1254	these same taxa	1240:1254	these same taxa	1240:1254	Many of these same taxa also had significant positive associations with cecal concentrations of butyrate, valerate, caproate, even though they are not known to produce these SCFAs.					
35532355	7	139	theme	SCFAs	1613:1617	arg1	production					1591:1600	the production	1587:1600	the production of certain SCFAs	1587:1617	Together, these data suggest the RPS-associated reduction in Salmonella shedding may be dependent on the establishment of bacterial cross feeding interactions that result in the production of certain SCFAs.					
35532355	11	140	theme	enterica	2061:2068	arg1	I					2078:2078	Salmonella enterica serovar I 4,[5]	2050:2084	I	2078:2078	Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides in the intestines of pigs without disease, but can make humans sick if unintentionally consumed.					
35532355	4	141	theme	RPS	849:851	arg1	group					863:867	the RPS treatment group	845:867	the RPS treatment group	845:867	Within the RPS treatment group, pigs shedding the least Salmonella tended to have greater cecal concentrations of butyrate, valerate, caproate, and succinate.					
35532355	9	142	theme	12	1805:1806	arg1	I					1797:1797	S. enterica serovar I 4,[5]	1777:1803	I	1797:1797	RPS supplementation could be an effective means to reduce multidrug-resistant (MDR) S. enterica serovar I 4,[5],12:i:- in swine, provided appropriate bacterial communities are present in the gut.					
35532355	3	143	theme	fatty	782:786	arg1	SCFA					794:797	SCFA	794:797	SCFA	794:797	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	3	143	theme	fatty	782:786	arg1	acid					788:791	cecal short chain fatty acid	764:791	different cecal short chain fatty acid (SCFA) profiles relative to control animals	754:835	Only RPS-fed pigs exhibited a reduction in Salmonella fecal shedding, different bacterial community compositions, and different cecal short chain fatty acid (SCFA) profiles relative to control animals.					
35532355	5	144	theme	negative	1123:1130	arg1	relationships					1132:1144	negative relationships	1123:1144	negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts	1123:1229	Additionally, among RPS-fed pigs, several bacterial taxa (Prevotella_7, Olsenella, and Bifidobacterium, and others) exhibited negative relationships between their abundances of and the amount of Salmonella in the feces of their hosts.					
35754398	4	0	theme	stable	744:749	arg1	conformers					751:760	the most stable conformers	735:760	the most stable conformers using energy calculations	735:786	We demonstrate that identifying the most stable conformers using energy calculations is challenging and computing of NMR shieldings is typically not sensitive enough.					
35754398	2	1	theme	dynamic	381:387	arg1	equilibria					404:413	resulting dynamic conformational equilibria	371:413	resulting dynamic conformational equilibria	371:413	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	1	2	theme	monosaccharides	157:171	arg1	properties					143:152	The conformational properties	124:152	The conformational properties of monosaccharides	124:171	The conformational properties of monosaccharides constitute fundamental features of oligosaccharides.					
35754398	6	3	theme	molecular	1247:1255	arg1	switch					1257:1262	a molecular switch	1245:1262	a molecular switch	1245:1262	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	5	4	theme	different	1070:1078	arg1	conformers					1080:1089	different conformers	1070:1089	different conformers	1070:1089	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	6	5	theme	diamino-xyloside	1210:1225	arg1	equilibrium					1193:1203	a hitherto unknown dynamic equilibrium	1166:1203	a hitherto unknown dynamic equilibrium of a diamino-xyloside	1166:1225	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	6	5	theme	diamino-xyloside	1210:1225	arg1	precursor					1232:1240	a precursor	1230:1240	a precursor of a molecular switch	1230:1262	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	3	6	theme	parameters	563:572	arg1	combination					531:541	a combination	529:541	a combination of experimental NMR parameters and computed molecular properties	529:606	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	3	7	theme	molecular	587:595	arg1	properties					597:606	computed molecular properties	578:606	computed molecular properties	578:606	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	5	8	theme	experimental	985:996	arg1	data					1002:1005	experimental NMR data	985:1005	experimental NMR data of dynamic conformational equilibria	985:1042	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	5	9	theme	conformational	1018:1031	arg1	equilibria					1033:1042	dynamic conformational equilibria	1010:1042	dynamic conformational equilibria	1010:1042	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	2	10	theme	biochemical	301:311	arg1	environment					313:323	a specific biochemical environment	290:323	a specific biochemical environment	290:323	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	0	11	theme	Dynamics	101:108	arg1	Determination					65:77	the Determination	61:77	the Determination of the Conformational Dynamics of Xylosides	61:121	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	6	12	theme	unknown	1177:1183	arg1	equilibrium					1193:1203	a hitherto unknown dynamic equilibrium	1166:1203	a hitherto unknown dynamic equilibrium of a diamino-xyloside	1166:1225	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	6	12	theme	unknown	1177:1183	arg1	precursor					1232:1240	a precursor	1230:1240	a precursor of a molecular switch	1230:1262	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	3	13	theme	β-d-xylopyranosides	486:504	arg1	series					476:481	a series	474:481	a series of β-d-xylopyranosides	474:504	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	2	14	theme	specific	292:299	arg1	environment					313:323	a specific biochemical environment	290:323	a specific biochemical environment	290:323	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	5	15	theme	coupling	908:915	arg1	constants					917:925	computed spin-spin coupling constants	889:925	computed spin-spin coupling constants for the xyloside ring	889:947	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	0	16	theme	Conformational	86:99	arg1	Dynamics					101:108	the Conformational Dynamics	82:108	the Conformational Dynamics of Xylosides	82:121	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	3	17	theme	NMR	559:561	arg1	parameters					563:572	experimental NMR parameters	546:572	experimental NMR parameters	546:572	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	1	18	theme	fundamental	184:194	arg1	features					196:203	fundamental features	184:203	fundamental features of oligosaccharides	184:223	The conformational properties of monosaccharides constitute fundamental features of oligosaccharides.					
35754398	3	19	theme	properties	597:606	arg1	combination					531:541	a combination	529:541	a combination of experimental NMR parameters and computed molecular properties	529:606	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	0	20	theme	Between	0:6	arg1	Chairs					12:17	Two Chairs	8:17	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.	0:122	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	2	21	theme	chemical	331:338	arg1	modifications					340:352	chemical modifications	331:352	chemical modifications	331:352	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	4	22	theme	NMR	820:822	arg1	shieldings					824:833	NMR shieldings	820:833	NMR shieldings	820:833	We demonstrate that identifying the most stable conformers using energy calculations is challenging and computing of NMR shieldings is typically not sensitive enough.					
35754398	0	23	theme	Xylosides	113:121	arg1	Dynamics					101:108	the Conformational Dynamics	82:108	the Conformational Dynamics of Xylosides	82:121	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	3	24	theme	computed	578:585	arg1	properties					597:606	computed molecular properties	578:606	computed molecular properties	578:606	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	2	25	theme	monosaccharides	256:270	arg1	landscape					243:251	the energy landscape	232:251	the energy landscape of monosaccharides	232:270	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	1	26	theme	oligosaccharides	208:223	arg1	features					196:203	fundamental features	184:203	fundamental features of oligosaccharides	184:223	The conformational properties of monosaccharides constitute fundamental features of oligosaccharides.					
35754398	5	27	theme	NMR	998:1000	arg1	data					1002:1005	experimental NMR data	985:1005	experimental NMR data of dynamic conformational equilibria	985:1042	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	3	28	theme	experimental	546:557	arg1	parameters					563:572	experimental NMR parameters	546:572	experimental NMR parameters	546:572	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	3	29	theme	conformational	676:689	arg1	equilibria					691:700	conformational equilibria	676:700	conformational equilibria	676:700	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	2	30	theme	resulting	371:379	arg1	equilibria					404:413	resulting dynamic conformational equilibria	371:413	resulting dynamic conformational equilibria	371:413	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	1	31	theme	conformational	128:141	arg1	properties					143:152	The conformational properties	124:152	The conformational properties of monosaccharides	124:171	The conformational properties of monosaccharides constitute fundamental features of oligosaccharides.					
35754398	5	32	theme	dynamic	1010:1016	arg1	equilibria					1033:1042	dynamic conformational equilibria	1010:1042	dynamic conformational equilibria	1010:1042	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	3	33	theme	equilibria	691:700	arg1	composition					661:671	the composition	657:671	the composition of conformational equilibria	657:700	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	3	34	used	used	509:512	arg2	series					476:481	a series	474:481	a series of β-d-xylopyranosides	474:504	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	5	35	theme	computed	889:896	arg1	constants					917:925	computed spin-spin coupling constants	889:925	computed spin-spin coupling constants for the xyloside ring	889:947	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	5	36	theme	conformers	1080:1089	arg1	ratio					1061:1065	the ratio	1057:1065	the ratio of different conformers	1057:1089	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	2	37	theme	experimental	434:445	arg1	means					447:451	experimental means	434:451	experimental means alone	434:457	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	5	38	theme	xyloside	935:942	arg1	ring					944:947	the xyloside ring	931:947	the xyloside ring	931:947	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	5	39	theme	other	877:881	arg1	hand					883:886	the other hand	873:886	the other hand	873:886	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	5	40	theme	equilibria	1033:1042	arg1	data					1002:1005	experimental NMR data	985:1005	experimental NMR data of dynamic conformational equilibria	985:1042	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	3	41	used	used	615:618	arg2	combination					531:541	a combination	529:541	a combination of experimental NMR parameters and computed molecular properties	529:606	In this work, a series of β-d-xylopyranosides is used to outline how a combination of experimental NMR parameters and computed molecular properties can be used to determine conformers and quantify the composition of conformational equilibria.					
35754398	0	42	theme	Theory	35:40	arg1	Combination					20:30	Combination	20:30	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.	0:122	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	2	43	theme	energy	236:241	arg1	landscape					243:251	the energy landscape	232:251	the energy landscape of monosaccharides	232:270	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	6	44	theme	switch	1257:1262	arg1	equilibrium					1193:1203	a hitherto unknown dynamic equilibrium	1166:1203	a hitherto unknown dynamic equilibrium of a diamino-xyloside	1166:1225	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	6	44	theme	switch	1257:1262	arg1	precursor					1232:1240	a precursor	1230:1240	a precursor of a molecular switch	1230:1262	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	4	45	dep	identifying	723:733	arg1	computing					807:815	computing	807:815	computing	807:815	We demonstrate that identifying the most stable conformers using energy calculations is challenging and computing of NMR shieldings is typically not sensitive enough.					
35754398	4	45	dep	identifying	723:733	arg1	challenging					791:801	challenging	791:801	challenging	791:801	We demonstrate that identifying the most stable conformers using energy calculations is challenging and computing of NMR shieldings is typically not sensitive enough.					
35754398	0	46	dep	Chairs	12:17	arg1	Combination					20:30	Combination	20:30	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.	0:122	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	4	47	theme	energy	768:773	arg1	calculations					775:786	energy calculations	768:786	energy calculations	768:786	We demonstrate that identifying the most stable conformers using energy calculations is challenging and computing of NMR shieldings is typically not sensitive enough.					
35754398	5	48	theme	spin-spin	898:906	arg1	constants					917:925	computed spin-spin coupling constants	889:925	computed spin-spin coupling constants for the xyloside ring	889:947	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	2	49	theme	equilibria	404:413	arg1	analysis					359:366	the analysis	355:366	the analysis of resulting dynamic conformational equilibria	355:413	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	2	49	theme	equilibria	404:413	arg1	feasible					422:429	feasible	422:429	feasible	422:429	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
35754398	6	50	theme	principle	1121:1129	arg1	proof					1112:1116	a proof	1110:1116	a proof of principle	1110:1129	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	0	51	theme	Experiment	46:55	arg1	Combination					20:30	Combination	20:30	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.	0:122	Between Two Chairs: Combination of Theory and Experiment for the Determination of the Conformational Dynamics of Xylosides.					
35754398	6	52	theme	dynamic	1185:1191	arg1	equilibrium					1193:1203	a hitherto unknown dynamic equilibrium	1166:1203	a hitherto unknown dynamic equilibrium of a diamino-xyloside	1166:1225	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	6	52	theme	dynamic	1185:1191	arg1	precursor					1232:1240	a precursor	1230:1240	a precursor of a molecular switch	1230:1262	As a proof of principle, this procedure allowed to analyze a hitherto unknown dynamic equilibrium of a diamino-xyloside as a precursor of a molecular switch.					
35754398	5	53	used	used	956:959	arg2	constants					917:925	computed spin-spin coupling constants	889:925	computed spin-spin coupling constants for the xyloside ring	889:947	On the other hand, computed spin-spin coupling constants for the xyloside ring can be used to unambiguously assign experimental NMR data of dynamic conformational equilibria and quantify the ratio of different conformers in the mixture.					
35754398	2	54	theme	conformational	389:402	arg1	equilibria					404:413	resulting dynamic conformational equilibria	371:413	resulting dynamic conformational equilibria	371:413	While the energy landscape of monosaccharides can be altered by a specific biochemical environment or by chemical modifications, the analysis of resulting dynamic conformational equilibria is not feasible by experimental means alone.					
36657833	5	0	theme	@	757:757	arg1	film					761:764	the C3N4-PDA-Ag@CS film	742:764	the C3N4-PDA-Ag@CS film	742:764	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	8	1	contain	has	1306:1308	arg1	dressing					1297:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	1	contain	has	1306:1308	arg2	biocompatibility					1346:1361	biocompatibility	1346:1361	biocompatibility	1346:1361	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	1	contain	has	1306:1308	arg2	properties					1334:1343	excellent antibacterial properties	1310:1343	excellent antibacterial properties	1310:1343	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	0	2	with	dressing	60:67	arg1	properties					88:97	antibacterial properties	74:97	antibacterial properties	74:97	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	4	3	theme	C3N4-PDA-Ag	695:705	arg1	film					710:713	a C3N4-PDA-Ag@CS film	693:713	a C3N4-PDA-Ag@CS film	693:713	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	5	4	theme	CS	758:759	arg1	film					761:764	the C3N4-PDA-Ag@CS film	742:764	the C3N4-PDA-Ag@CS film	742:764	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	7	5	theme	collagen	1141:1148	arg1	deposition					1150:1159	collagen deposition	1141:1159	collagen deposition	1141:1159	In addition, the composite dressing promoted wound healing in infected mice by facilitating collagen deposition and accelerating epidermal regeneration.					
36657833	8	6	theme	C3N4-PDA-Ag	1272:1282	arg1	dressing					1297:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	6	7	theme	in	1010:1011	arg1	biocompatibility					1031:1046	excellent in vitro and in vivo biocompatibility	1000:1046	excellent in vitro and in vivo biocompatibility	1000:1046	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	6	8	theme	cytotoxicity	905:916	arg1	experiments					944:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	1	9	theme	major	141:145	arg1	barrier					156:162	a major clinical barrier	139:162	a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance	139:255	Infection represents a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance.					
36657833	6	10	theme	excellent	1000:1008	arg1	biocompatibility					1031:1046	excellent in vitro and in vivo biocompatibility	1000:1046	excellent in vitro and in vivo biocompatibility	1000:1046	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	6	11	contain	possesses	990:998	arg2	biocompatibility					1031:1046	excellent in vitro and in vivo biocompatibility	1000:1046	excellent in vitro and in vivo biocompatibility	1000:1046	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	6	11	contain	possesses	990:998	arg1	film					985:988	the composite film	971:988	the composite film	971:988	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	6	12	dep	in	1023:1024	arg1	vivo					1026:1029	vivo	1026:1029	vivo	1026:1029	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	6	13	theme	implantation	931:942	arg1	experiments					944:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	8	14	theme	wound	1377:1381	arg1	healing					1383:1389	wound healing	1377:1389	wound healing	1377:1389	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	4	15	theme	CS	707:708	arg1	film					710:713	a C3N4-PDA-Ag@CS film	693:713	a C3N4-PDA-Ag@CS film	693:713	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	8	16	theme	composite	1287:1295	arg1	dressing					1297:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	17	theme	CS	1284:1285	arg1	dressing					1297:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	3	18	theme	photocatalyst	451:463	arg1	C3N4					465:468	the photocatalyst C3N4	447:468	the photocatalyst C3N4	447:468	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	5	19	theme	antibacterial	784:796	arg1	activity					798:805	superior antibacterial activity	775:805	superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa	775:862	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	7	20	theme	infected	1111:1118	arg1	mice					1120:1123	infected mice	1111:1123	infected mice	1111:1123	In addition, the composite dressing promoted wound healing in infected mice by facilitating collagen deposition and accelerating epidermal regeneration.					
36657833	3	21	theme	C3N4	465:468	arg1	nanoparticles					481:493	the photocatalyst C3N4 and silver nanoparticles	447:493	the photocatalyst C3N4 and silver nanoparticles (Ag NPs)	447:502	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	21	theme	C3N4	465:468	arg1	NPs					499:501	Ag NPs	496:501	Ag NPs	496:501	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	0	22	theme	carbon	15:20	arg1	dressing					60:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing	0:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.	0:116	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	7	23	theme	wound	1094:1098	arg1	healing					1100:1106	wound healing	1094:1106	wound healing	1094:1106	In addition, the composite dressing promoted wound healing in infected mice by facilitating collagen deposition and accelerating epidermal regeneration.					
36657833	2	24	theme	dressing	320:327	arg1	type					312:315	a new type	306:315	a new type of dressing	306:327	Hence, it is of particular important to develop a new type of dressing to combat bacterial resistance.					
36657833	6	25	theme	hemolysis	894:902	arg1	experiments					944:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments	890:954	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	5	26	theme	CS	880:881	arg1	group					883:887	the CS group	876:887	the CS group	876:887	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	0	27	theme	Chitosan-based	0:13	arg1	dressing					60:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing	0:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.	0:116	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	4	28	with	compounding	642:652	arg1	CS					672:673	CS	672:673	CS	672:673	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	4	28	with	compounding	642:652	arg1	chitosan					662:669	chitosan	662:669	chitosan (CS)	662:674	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	1	29	theme	antibiotics	212:222	arg1	overuse					201:207	the overuse	197:207	the overuse of antibiotics	197:222	Infection represents a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance.					
36657833	3	30	theme	carbon	371:376	arg1	complex					406:412	a carbon nitride-polydopamine‑silver complex	369:412	a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag)	369:426	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	30	theme	carbon	371:376	arg1	C3N4-PDA-Ag					415:425	C3N4-PDA-Ag	415:425	C3N4-PDA-Ag	415:425	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	4	31	theme	casting	564:570	arg1	method					572:577	The solution casting method	551:577	The solution casting method	551:577	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	8	32	theme	photocatalytic	1441:1454	arg1	materials					1456:1464	photocatalytic materials	1441:1464	photocatalytic materials	1441:1464	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	3	33	theme	nitride-polydopamine‑silver	378:404	arg1	complex					406:412	a carbon nitride-polydopamine‑silver complex	369:412	a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag)	369:426	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	33	theme	nitride-polydopamine‑silver	378:404	arg1	C3N4-PDA-Ag					415:425	C3N4-PDA-Ag	415:425	C3N4-PDA-Ag	415:425	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	8	34	theme	wounds	1496:1501	arg1	treatment					1474:1482	the treatment	1470:1482	the treatment of infected wounds	1470:1501	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	2	35	theme	new	308:310	arg1	type					312:315	a new type	306:315	a new type of dressing	306:327	Hence, it is of particular important to develop a new type of dressing to combat bacterial resistance.					
36657833	1	36	theme	wound	176:180	arg1	healing					182:188	wound healing	176:188	wound healing	176:188	Infection represents a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance.					
36657833	4	37	theme	@	706:706	arg1	film					710:713	a C3N4-PDA-Ag@CS film	693:713	a C3N4-PDA-Ag@CS film	693:713	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	8	38	theme	infected	1487:1494	arg1	wounds					1496:1501	infected wounds	1487:1501	infected wounds	1487:1501	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	39	theme	@	1283:1283	arg1	dressing					1297:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	the C3N4-PDA-Ag@CS composite dressing	1268:1304	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	40	theme	excellent	1310:1318	arg1	biocompatibility					1346:1361	biocompatibility	1346:1361	biocompatibility	1346:1361	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	40	theme	excellent	1310:1318	arg1	properties					1334:1343	excellent antibacterial properties	1310:1343	excellent antibacterial properties	1310:1343	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	7	41	theme	epidermal	1178:1186	arg1	regeneration					1188:1199	epidermal regeneration	1178:1199	epidermal regeneration	1178:1199	In addition, the composite dressing promoted wound healing in infected mice by facilitating collagen deposition and accelerating epidermal regeneration.					
36657833	6	42	dep	in	923:924	arg1	vivo					926:929	vivo	926:929	vivo	926:929	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	7	43	theme	composite	1066:1074	arg1	dressing					1076:1083	the composite dressing	1062:1083	the composite dressing	1062:1083	In addition, the composite dressing promoted wound healing in infected mice by facilitating collagen deposition and accelerating epidermal regeneration.					
36657833	0	44	theme	composite	50:58	arg1	dressing					60:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing	0:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.	0:116	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	1	45	theme	bacterial	236:244	arg1	resistance					246:255	bacterial resistance	236:255	bacterial resistance	236:255	Infection represents a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance.					
36657833	5	46	theme	superior	775:782	arg1	activity					798:805	superior antibacterial activity	775:805	superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa	775:862	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	8	47	theme	study	1237:1241	arg1	findings					1220:1227	the findings	1216:1227	the findings of this study	1216:1241	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	6	48	theme	composite	975:983	arg1	film					985:988	the composite film	971:988	the composite film	971:988	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	8	49	theme	materials	1456:1464	arg1	application					1426:1436	the application	1422:1436	the application of photocatalytic materials	1422:1464	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	1	50	theme	clinical	147:154	arg1	barrier					156:162	a major clinical barrier	139:162	a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance	139:255	Infection represents a major clinical barrier that delays wound healing, while the overuse of antibiotics can lead to bacterial resistance.					
36657833	0	51	theme	antibacterial	74:86	arg1	properties					88:97	antibacterial properties	74:97	antibacterial properties	74:97	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	4	52	theme	solution	555:562	arg1	method					572:577	The solution casting method	551:577	The solution casting method	551:577	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	4	53	dep	compounding	642:652	arg1	it					654:655	it	654:655	it	654:655	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	2	54	theme	bacterial	339:347	arg1	resistance					349:358	bacterial resistance	339:358	bacterial resistance	339:358	Hence, it is of particular important to develop a new type of dressing to combat bacterial resistance.					
36657833	2	55	theme	particular	274:283	arg1	important					285:293	important	285:293	important	285:293	Hence, it is of particular important to develop a new type of dressing to combat bacterial resistance.					
36657833	3	56	theme	Ag	496:497	arg1	nanoparticles					481:493	the photocatalyst C3N4 and silver nanoparticles	447:493	the photocatalyst C3N4 and silver nanoparticles (Ag NPs)	447:502	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	56	theme	Ag	496:497	arg1	NPs					499:501	Ag NPs	496:501	Ag NPs	496:501	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	4	57	theme	C3N4-PDA-Ag	619:629	arg1	complex					631:637	the C3N4-PDA-Ag complex	615:637	the C3N4-PDA-Ag complex	615:637	The solution casting method was then employed to further modify the C3N4-PDA-Ag complex by compounding it with chitosan (CS), thereby forming a C3N4-PDA-Ag@CS film.					
36657833	6	58	dep	in	1010:1011	arg1	vitro					1013:1017	vitro	1013:1017	vitro	1013:1017	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	0	59	theme	wound	103:107	arg1	healing					109:115	wound healing	103:115	wound healing	103:115	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	3	60	theme	silver	474:479	arg1	nanoparticles					481:493	the photocatalyst C3N4 and silver nanoparticles	447:493	the photocatalyst C3N4 and silver nanoparticles (Ag NPs)	447:502	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	60	theme	silver	474:479	arg1	NPs					499:501	Ag NPs	496:501	Ag NPs	496:501	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	3	61	theme	synergistic	517:527	arg1	effect					543:548	a synergistic antimicrobial effect	515:548	a synergistic antimicrobial effect	515:548	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	6	62	theme	in	1023:1024	arg1	biocompatibility					1031:1046	excellent in vitro and in vivo biocompatibility	1000:1046	excellent in vitro and in vivo biocompatibility	1000:1046	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	5	63	theme	C3N4-PDA-Ag	746:756	arg1	film					761:764	the C3N4-PDA-Ag@CS film	742:764	the C3N4-PDA-Ag@CS film	742:764	The results revealed that the C3N4-PDA-Ag@CS film exhibits superior antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa compared to the CS group.					
36657833	6	64	theme	in	923:924	arg1	implantation					931:942	in vivo implantation	923:942	in vivo implantation	923:942	The hemolysis, cytotoxicity, and in vivo implantation experiments indicated that the composite film possesses excellent in vitro and in vivo biocompatibility.					
36657833	0	65	theme	nitride-polydopamine‑silver	22:48	arg1	dressing					60:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing	0:67	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.	0:116	Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing.					
36657833	3	66	theme	antimicrobial	529:541	arg1	effect					543:548	a synergistic antimicrobial effect	515:548	a synergistic antimicrobial effect	515:548	Herein, a carbon nitride-polydopamine‑silver complex (C3N4-PDA-Ag) was prepared using the photocatalyst C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect.					
36657833	8	67	theme	antibacterial	1320:1332	arg1	biocompatibility					1346:1361	biocompatibility	1346:1361	biocompatibility	1346:1361	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
36657833	8	67	theme	antibacterial	1320:1332	arg1	properties					1334:1343	excellent antibacterial properties	1310:1343	excellent antibacterial properties	1310:1343	Collectively, the findings of this study clearly demonstrate that the C3N4-PDA-Ag@CS composite dressing has excellent antibacterial properties, biocompatibility, and enhances wound healing, thus providing a strategy for the application of photocatalytic materials for the treatment of infected wounds.					
35108154	0	0	theme	Saccharomyces	15:27	arg1	powder					39:44	Saccharomyces boulardii powder	15:44	Saccharomyces boulardii powder	15:44	Preparation of Saccharomyces boulardii powder by spray drying: thermoprotectants optimization and stability evaluation.					
35108154	5	1	theme	skim	674:677	arg1	milk					679:682	: 15.12% skim milk	665:682	: 15.12% skim milk	665:682	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	6	2	theme	predicted	791:799	arg1	value					801:805	the predicted value	787:805	the predicted value of 18.21%	787:815	The highest viability was 17.77%, which was basically the same as the predicted value of 18.21%.					
35108154	8	3	theme	drying	1114:1119	arg1	process					1121:1127	the spray drying process	1104:1127	the spray drying process	1104:1127	This work provides a thermoprotectants formula for the S. boulardii during the spray drying process.					
35108154	1	4	used	used	178:181	arg2	boulardii					134:142	Saccharomyces boulardii	120:142	Saccharomyces boulardii as the probiotic yeast	120:165	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	8	5	theme	spray	1108:1112	arg1	process					1121:1127	the spray drying process	1104:1127	the spray drying process	1104:1127	This work provides a thermoprotectants formula for the S. boulardii during the spray drying process.					
35108154	2	6	theme	carbohydrates	273:285	arg1	influence					236:244	The influence	232:244	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii	232:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	7	7	theme	inactivation	822:833	arg1	constant					840:847	The inactivation rate constant	818:847	The inactivation rate constant of spray-dried powder	818:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	7	theme	inactivation	822:833	arg1	h-1					894:896	k-18 = 1.04 × 10-5 h-1	875:896	k-18 = 1.04 × 10-5 h-1	875:896	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	8	theme	powder	864:869	arg1	constant					840:847	The inactivation rate constant	818:847	The inactivation rate constant of spray-dried powder	818:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	8	theme	powder	864:869	arg1	h-1					894:896	k-18 = 1.04 × 10-5 h-1	875:896	k-18 = 1.04 × 10-5 h-1	875:896	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	9	theme	rate	835:838	arg1	constant					840:847	The inactivation rate constant	818:847	The inactivation rate constant of spray-dried powder	818:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	9	theme	rate	835:838	arg1	h-1					894:896	k-18 = 1.04 × 10-5 h-1	875:896	k-18 = 1.04 × 10-5 h-1	875:896	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	5	10	dep	milk	679:682	arg1	%					672:672	%	672:672	%	672:672	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	4	11	theme	accelerated	494:504	arg1	test					506:509	The accelerated test	490:509	The accelerated test	490:509	The accelerated test is applied to evaluate its the subsequent storage stability.					
35108154	2	12	from	influence	236:244	arg1	resistance					299:308	the heat resistance	290:308	the heat resistance of S. boulardii	290:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	1	13	theme	pharmaceutical	190:203	arg1	industries					220:229	the pharmaceutical, feed and food industries	186:229	the pharmaceutical, feed and food industries	186:229	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	8	14	theme	thermoprotectants	1050:1066	arg1	formula					1068:1074	a thermoprotectants formula	1048:1074	a thermoprotectants formula for the S. boulardii	1048:1095	This work provides a thermoprotectants formula for the S. boulardii during the spray drying process.					
35108154	0	15	dep	optimization	81:92	arg1	evaluation					108:117	evaluation	108:117	evaluation	108:117	Preparation of Saccharomyces boulardii powder by spray drying: thermoprotectants optimization and stability evaluation.					
35108154	3	16	theme	thermoprotectant	423:438	arg1	composition					440:450	the thermoprotectant composition	419:450	the thermoprotectant composition for S. boulardii during spray-drying	419:487	Response surface methodology was effectively applied to optimize the thermoprotectant composition for S. boulardii during spray-drying.					
35108154	3	17	theme	Response	354:361	arg1	methodology					371:381	Response surface methodology	354:381	Response surface methodology	354:381	Response surface methodology was effectively applied to optimize the thermoprotectant composition for S. boulardii during spray-drying.					
35108154	5	18	theme	thermoprotectants	598:614	arg1	composition					616:626	the thermoprotectants composition	594:626	the thermoprotectants composition	594:626	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	2	19	theme	heat	294:297	arg1	resistance					299:308	the heat resistance	290:308	the heat resistance of S. boulardii	290:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	7	20	theme	cells	922:926	arg1	quantity					903:910	the quantity	899:910	the quantity of viable cells stored at this temperature for 1 and 10 years	899:972	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	20	theme	cells	922:926	arg1	CFU/g					989:993	8.25 × 108 CFU/g	978:993	8.25 × 108 CFU/g	978:993	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	1	21	theme	feed	206:209	arg1	industries					220:229	the pharmaceutical, feed and food industries	186:229	the pharmaceutical, feed and food industries	186:229	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	3	22	theme	surface	363:369	arg1	methodology					371:381	Response surface methodology	354:381	Response surface methodology	354:381	Response surface methodology was effectively applied to optimize the thermoprotectant composition for S. boulardii during spray-drying.					
35108154	5	23	theme	9.73	704:707	arg1	trehalose					710:718	9.73% trehalose	704:718	9.73% trehalose	704:718	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	1	24	theme	Saccharomyces	120:132	arg1	boulardii					134:142	Saccharomyces boulardii	120:142	Saccharomyces boulardii as the probiotic yeast	120:165	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	7	25	theme	viable	915:920	arg1	cells					922:926	viable cells	915:926	viable cells stored at this temperature for 1 and 10 years	915:972	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	5	26	theme	%	708:708	arg1	trehalose					710:718	9.73% trehalose	704:718	9.73% trehalose	704:718	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	1	27	theme	food	215:218	arg1	industries					220:229	the pharmaceutical, feed and food industries	186:229	the pharmaceutical, feed and food industries	186:229	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	0	28	theme	powder	39:44	arg1	Preparation					0:10	Preparation	0:10	Preparation of Saccharomyces boulardii powder by spray drying:	0:61	Preparation of Saccharomyces boulardii powder by spray drying: thermoprotectants optimization and stability evaluation.					
35108154	0	29	theme	boulardii	29:37	arg1	powder					39:44	Saccharomyces boulardii powder	15:44	Saccharomyces boulardii powder	15:44	Preparation of Saccharomyces boulardii powder by spray drying: thermoprotectants optimization and stability evaluation.					
35108154	5	30	theme	1.81	685:688	arg1	%					689:689	%	689:689	%	689:689	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	0	31	theme	spray	49:53	arg1	drying					55:60	spray drying	49:60	spray drying	49:60	Preparation of Saccharomyces boulardii powder by spray drying: thermoprotectants optimization and stability evaluation.					
35108154	4	32	theme	storage	553:559	arg1	stability					561:569	the subsequent storage stability	538:569	its the subsequent storage stability	534:569	The accelerated test is applied to evaluate its the subsequent storage stability.					
35108154	5	33	theme	%	689:689	arg1	gelatin					691:697	1.81% gelatin	685:697	1.81% gelatin	685:697	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	6	34	theme	%	815:815	arg1	value					801:805	the predicted value	787:805	the predicted value of 18.21%	787:815	The highest viability was 17.77%, which was basically the same as the predicted value of 18.21%.					
35108154	7	35	theme	=	880:880	arg1	h-1					894:896	k-18 = 1.04 × 10-5 h-1	875:896	k-18 = 1.04 × 10-5 h-1	875:896	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	35	theme	=	880:880	arg1	constant					840:847	The inactivation rate constant	818:847	The inactivation rate constant of spray-dried powder	818:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	4	36	theme	subsequent	542:551	arg1	stability					561:569	the subsequent storage stability	538:569	its the subsequent storage stability	534:569	The accelerated test is applied to evaluate its the subsequent storage stability.					
35108154	2	37	theme	gelatin	260:266	arg1	influence					236:244	The influence	232:244	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii	232:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	2	38	theme	boulardii	316:324	arg1	resistance					299:308	the heat resistance	290:308	the heat resistance of S. boulardii	290:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	7	39	theme	1.04 × 10-5	882:892	arg1	h-1					894:896	k-18 = 1.04 × 10-5 h-1	875:896	k-18 = 1.04 × 10-5 h-1	875:896	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	7	39	theme	1.04 × 10-5	882:892	arg1	constant					840:847	The inactivation rate constant	818:847	The inactivation rate constant of spray-dried powder	818:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
35108154	5	40	dep	%	672:672	arg1	15.12					667:671	15.12	667:671	15.12	667:671	The results show that the thermoprotectants composition was comprehensively optimized such as: 15.12% skim milk, 1.81% gelatin, and 9.73% trehalose.					
35108154	1	41	theme	probiotic	151:159	arg1	yeast					161:165	the probiotic yeast	147:165	the probiotic yeast	147:165	Saccharomyces boulardii as the probiotic yeast was widely used in the pharmaceutical, feed and food industries.					
35108154	2	42	theme	milk	254:257	arg1	influence					236:244	The influence	232:244	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii	232:324	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	6	43	theme	highest	725:731	arg1	viability					733:741	The highest viability	721:741	The highest viability	721:741	The highest viability was 17.77%, which was basically the same as the predicted value of 18.21%.					
35108154	6	43	theme	highest	725:731	arg1	%					752:752	17.77%	747:752	17.77%	747:752	The highest viability was 17.77%, which was basically the same as the predicted value of 18.21%.					
35108154	2	44	theme	skim	249:252	arg1	milk					254:257	skim milk	249:257	skim milk	249:257	The influence of skim milk, gelatin, and carbohydrates on the heat resistance of S. boulardii is explored in the article.					
35108154	7	45	theme	spray-dried	852:862	arg1	powder					864:869	spray-dried powder	852:869	spray-dried powder	852:869	The inactivation rate constant of spray-dried powder was k-18 = 1.04 × 10-5 h-1, the quantity of viable cells stored at this temperature for 1 and 10 years was 8.25 × 108 CFU/g and 1.25 × 108 CFU/g, separately.					
36026574	4	0	theme	electrostatic	758:770	arg1	adsorption					772:781	electrostatic adsorption	758:781	electrostatic adsorption	758:781	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	6	1	theme	online	1405:1410	arg1	monitoring					1412:1421	real-time online monitoring	1395:1421	real-time online monitoring of NH<sub>3</sub> in the environment	1395:1458	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	5	2	theme	high	1004:1007	arg1	sensitivity					1009:1019	high sensitivity	1004:1019	high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1)	1004:1069	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	6	3	theme	real-time	1395:1403	arg1	monitoring					1412:1421	real-time online monitoring	1395:1421	real-time online monitoring of NH<sub>3</sub> in the environment	1395:1458	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	2	4	theme	materials	373:381	arg1	application					344:354	the application	340:354	the application of gas-sensitive materials	340:381	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	5	5	dep	loading	899:905	arg1	T<sub>x</sub>					936:948	T<sub>x</sub>	936:948	T<sub>x</sub>	936:948	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	6	theme	selectivity	1077:1087	arg1	response					1089:1096	high selectivity response	1072:1096	high selectivity response (37.6%)	1072:1104	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	6	theme	selectivity	1077:1087	arg1	%					1103:1103	37.6%	1099:1103	37.6%	1099:1103	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	7	theme	high	1072:1075	arg1	response					1089:1096	high selectivity response	1072:1096	high selectivity response (37.6%)	1072:1104	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	7	theme	high	1072:1075	arg1	%					1103:1103	37.6%	1099:1103	37.6%	1099:1103	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	7	8	theme	gas-sensitive	1540:1552	arg1	composites					1554:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	7	9	theme	sensing	1602:1608	arg1	analysis					1573:1580	the analysis	1569:1580	the analysis of self-powered gas sensing	1569:1608	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	7	10	theme	self-powered	1585:1596	arg1	sensing					1602:1608	self-powered gas sensing	1585:1608	self-powered gas sensing	1585:1608	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	1	11	theme	Gas-sensitive	83:95	arg1	materials					97:105	Gas-sensitive materials	83:105	Gas-sensitive materials	83:105	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	6	12	from	changes	1289:1295	arg1	range					1304:1308	the range	1300:1308	the range of 10-120 ppm	1300:1322	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	6	13	theme	ammonia-sensitive	1185:1201	arg1	material					1227:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	4	14	theme	electrostatic	790:802	arg1	field					804:808	the electrostatic field	786:808	the electrostatic field induced by triboelectricity	786:836	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	1	15	from	gases	180:184	arg1	environment					193:203	the environment	189:203	the environment	189:203	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	2	16	theme	adsorption	286:295	arg1	properties					297:306	weak adsorption properties	281:306	weak adsorption properties	281:306	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	2	16	theme	adsorption	286:295	arg1	challenge					321:329	the main challenge	312:329	the main challenge limiting the application of gas-sensitive materials	312:381	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	5	17	theme	V<sub>air</sub>	1031:1045	arg1	response					1021:1028	high sensitivity response	1004:1028	high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1)	1004:1069	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	17	theme	V<sub>air</sub>	1031:1045	arg1	/V<sub>gas</sub>					1047:1062	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	18	theme	fast	970:973	arg1	response/recovery					975:991	a fast response/recovery	968:991	a fast response/recovery (12/14 s)	968:1001	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	18	theme	fast	970:973	arg1	12/14 s					994:1000	12/14 s	994:1000	12/14 s	994:1000	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	19	theme	sensitivity	1009:1019	arg1	response					1021:1028	high sensitivity response	1004:1028	high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1)	1004:1069	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	19	theme	sensitivity	1009:1019	arg1	/V<sub>gas</sub>					1047:1062	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	20	theme	ammonia-sensitive	860:876	arg1	material					878:885	the ammonia-sensitive material	856:885	the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF	856:962	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	1	21	from	monitoring	157:166	arg1	environment					193:203	the environment	189:203	the environment	189:203	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	2	22	theme	weak	281:284	arg1	properties					297:306	weak adsorption properties	281:306	weak adsorption properties	281:306	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	2	22	theme	weak	281:284	arg1	challenge					321:329	the main challenge	312:329	the main challenge limiting the application of gas-sensitive materials	312:381	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	0	23	theme	Cellulosic	14:23	arg1	Materials					39:47	Gas-Sensitive Cellulosic Triboelectric Materials	0:47	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.	0:81	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.					
36026574	7	24	theme	gas	1598:1600	arg1	sensing					1602:1608	self-powered gas sensing	1585:1608	self-powered gas sensing	1585:1608	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	5	25	contain	has	964:966	arg2	response/recovery					975:991	a fast response/recovery	968:991	a fast response/recovery (12/14 s)	968:1001	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	limit					1125:1129	low detection limit	1111:1129	low detection limit (10 ppm)	1111:1138	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	12/14 s					994:1000	12/14 s	994:1000	12/14 s	994:1000	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	response					1021:1028	high sensitivity response	1004:1028	high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1)	1004:1069	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	/V<sub>gas</sub>					1047:1062	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	V<sub>air</sub> /V<sub>gas</sub> = 2.1	1031:1068	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	%					1103:1103	37.6%	1099:1103	37.6%	1099:1103	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	response					1089:1096	high selectivity response	1072:1096	high selectivity response (37.6%)	1072:1104	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg2	10 ppm					1132:1137	10 ppm	1132:1137	10 ppm	1132:1137	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	25	contain	has	964:966	arg1	material					878:885	the ammonia-sensitive material	856:885	the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF	856:962	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	6	26	theme	NH<sub>3</sub>	1260:1273	arg1	changes					1289:1295	NH<sub>3</sub> concentration changes	1260:1295	NH<sub>3</sub> concentration changes in the range of 10-120 ppm	1260:1322	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	6	27	theme	NH<sub>3</sub>	1426:1439	arg1	monitoring					1412:1421	real-time online monitoring	1395:1421	real-time online monitoring of NH<sub>3</sub> in the environment	1395:1458	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	3	28	theme	triboelectric	450:462	arg1	material					464:471	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material	384:471	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure	384:496	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	0	29	theme	Gas-Sensitive	0:12	arg1	Materials					39:47	Gas-Sensitive Cellulosic Triboelectric Materials	0:47	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.	0:81	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.					
36026574	4	30	theme	material	742:749	arg1	adsorption					724:733	the adsorption	720:733	the adsorption of the material due to electrostatic adsorption	720:781	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	2	31	theme	main	316:319	arg1	properties					297:306	weak adsorption properties	281:306	weak adsorption properties	281:306	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	2	31	theme	main	316:319	arg1	challenge					321:329	the main challenge	312:329	the main challenge limiting the application of gas-sensitive materials	312:381	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	6	32	theme	wirelessly	1348:1357	arg1	signal					1341:1346	the signal	1337:1346	the signal wirelessly to the user interface	1337:1379	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	0	33	theme	Triboelectric	25:37	arg1	Materials					39:47	Gas-Sensitive Cellulosic Triboelectric Materials	0:47	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.	0:81	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.					
36026574	1	34	theme	identification	130:143	arg1	capable					111:117	capable	111:117	capable	111:117	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	3	35	theme	self-powered	536:547	arg1	sensing					553:559	self-powered gas sensing	536:559	self-powered gas sensing	536:559	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	0	36	theme	Self-Powered	53:64	arg1	Sensing					74:80	Self-Powered Ammonia Sensing	53:80	Self-Powered Ammonia Sensing	53:80	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.					
36026574	6	37	theme	triboelectric	1213:1225	arg1	material					1227:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	5	38	theme	ammonia	1155:1161	arg1	gas					1163:1165	ammonia gas	1155:1165	ammonia gas	1155:1165	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	39	theme	low	1111:1113	arg1	10 ppm					1132:1137	10 ppm	1132:1137	10 ppm	1132:1137	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	39	theme	low	1111:1113	arg1	limit					1125:1129	low detection limit	1111:1129	low detection limit (10 ppm)	1111:1138	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	1	40	theme	dynamic	122:128	arg1	identification					130:143	dynamic identification	122:143	dynamic identification	122:143	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	3	41	theme	layered	480:486	arg1	structure					488:496	a layered structure	478:496	a layered structure	478:496	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	3	42	theme	-based	443:448	arg1	material					464:471	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material	384:471	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure	384:496	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	6	43	theme	CNF-based	1203:1211	arg1	material					1227:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	the ammonia-sensitive CNF-based triboelectric material	1181:1234	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	7	44	theme	preparing	1513:1521	arg1	composites					1554:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	5	45	theme	gas	1163:1165	arg1	100 ppm					1144:1150	100 ppm	1144:1150	100 ppm of ammonia gas	1144:1165	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	4	46	theme	material	694:701	arg1	structure					574:582	The layered structure	562:582	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	562:701	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	6	47	from	monitoring	1412:1421	arg1	environment					1448:1458	the environment	1444:1458	the environment	1444:1458	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	5	48	from	loading	899:905	arg1	PFOTES-CNF					953:962	PFOTES-CNF	953:962	PFOTES-CNF	953:962	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	2	49	theme	gas-sensitive	359:371	arg1	materials					373:381	gas-sensitive materials	359:381	gas-sensitive materials	359:381	However, weak adsorption properties are the main challenge limiting the application of gas-sensitive materials.					
36026574	0	50	theme	Ammonia	66:72	arg1	Sensing					74:80	Self-Powered Ammonia Sensing	53:80	Self-Powered Ammonia Sensing	53:80	Gas-Sensitive Cellulosic Triboelectric Materials for Self-Powered Ammonia Sensing.					
36026574	4	51	theme	layered	566:572	arg1	structure					574:582	The layered structure	562:582	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	562:701	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	3	52	with	material	464:471	arg1	structure					488:496	a layered structure	478:496	a layered structure	478:496	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	7	53	theme	designing	1499:1507	arg1	composites					1554:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	6	54	theme	user	1366:1369	arg1	interface					1371:1379	the user interface	1362:1379	the user interface	1362:1379	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	1	55	from	applications	216:227	arg1	field					236:240	the field	232:240	the field of gas sensing	232:255	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	56	theme	content	149:155	arg1	monitoring					157:166	content monitoring	149:166	content monitoring	149:166	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	5	57	theme	detection	1115:1123	arg1	10 ppm					1132:1137	10 ppm	1132:1137	10 ppm	1132:1137	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	5	57	theme	detection	1115:1123	arg1	limit					1125:1129	low detection limit	1111:1129	low detection limit (10 ppm)	1111:1138	It is found that the ammonia-sensitive material obtained by loading Ti<sub>3</sub> C<sub>2</sub> T<sub>x</sub> in PFOTES-CNF has a fast response/recovery (12/14 s), high sensitivity response (V<sub>air</sub> /V<sub>gas</sub> = 2.1), high selectivity response (37.6%), and low detection limit (10 ppm) for 100 ppm of ammonia gas.					
36026574	1	58	theme	monitoring	157:166	arg1	capable					111:117	capable	111:117	capable	111:117	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	59	from	identification	130:143	arg1	environment					193:203	the environment	189:203	the environment	189:203	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	4	60	theme	-based	673:678	arg1	material					694:701	the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	587:701	the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	587:701	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36026574	6	61	theme	concentration	1275:1287	arg1	changes					1289:1295	NH<sub>3</sub> concentration changes	1260:1295	NH<sub>3</sub> concentration changes in the range of 10-120 ppm	1260:1322	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	6	62	theme	10-120 ppm	1313:1322	arg1	range					1304:1308	the range	1300:1308	the range of 10-120 ppm	1300:1322	In addition, the ammonia-sensitive CNF-based triboelectric material can accurately identify NH<sub>3</sub> concentration changes in the range of 10-120 ppm and transmit the signal wirelessly to the user interface, facilitating real-time online monitoring of NH<sub>3</sub> in the environment.					
36026574	3	63	theme	gas	549:551	arg1	sensing					553:559	self-powered gas sensing	536:559	self-powered gas sensing	536:559	A highly adsorbent gas-sensitive cellulose nanofibril (CNF)-based triboelectric material with a layered structure is prepared here and it is applied to self-powered gas sensing.					
36026574	1	64	theme	gas	245:247	arg1	sensing					249:255	gas sensing	245:255	gas sensing	245:255	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	7	65	theme	novel	1463:1467	arg1	strategy					1469:1476	A novel strategy	1461:1476	A novel strategy	1461:1476	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	1	66	theme	specific	171:178	arg1	gases					180:184	specific gases	171:184	specific gases in the environment	171:203	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	67	theme	sensing	249:255	arg1	field					236:240	the field	232:240	the field of gas sensing	232:255	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	68	from	environment	193:203	arg1	monitoring					157:166	content monitoring	149:166	content monitoring	149:166	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	68	from	environment	193:203	arg1	identification					130:143	dynamic identification	122:143	dynamic identification	122:143	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	69	theme	gases	180:184	arg1	monitoring					157:166	content monitoring	149:166	content monitoring	149:166	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	1	69	theme	gases	180:184	arg1	identification					130:143	dynamic identification	122:143	dynamic identification	122:143	Gas-sensitive materials are capable of dynamic identification and content monitoring of specific gases in the environment, and their applications in the field of gas sensing are promising.					
36026574	7	70	theme	high-performance	1523:1538	arg1	composites					1554:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	designing and preparing high-performance gas-sensitive composites	1499:1563	A novel strategy is provided here for designing and preparing high-performance gas-sensitive composites and the analysis of self-powered gas sensing is guided.					
36026574	4	71	theme	gas-sensitive	680:692	arg1	material					694:701	the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	587:701	the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material	587:701	The layered structure of the triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane cellulose nanofiber (PFOTES-CNF)-based gas-sensitive material further enhances the adsorption of the material due to electrostatic adsorption in the electrostatic field induced by triboelectricity.					
36642127	6	0	theme	Cs/PVA/Sep	954:963	arg1	membrane					965:972	Cs/PVA/Sep membrane	954:972	Cs/PVA/Sep membrane	954:972	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	10	1	from	intercalation	1710:1722	arg1	layers					1736:1741	Sepolite layers	1727:1741	Sepolite layers	1727:1741	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	10	2	theme	%	1623:1623	arg1	values					1625:1630	% values	1623:1630	the water uptake % values	1606:1630	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	10	3	theme	groups	1691:1696	arg1	weakness					1653:1660	weakness	1653:1660	weakness in H-bonding (of hydrophilic groups)	1653:1697	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	10	4	theme	water	1610:1614	arg1	uptake					1616:1621	the water uptake % values	1606:1630	the water uptake % values	1606:1630	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	7	5	theme	Cs/PVA/Sep	1146:1155	arg1	membrane					1157:1164	the Cs/PVA/Sep membrane	1142:1164	the Cs/PVA/Sep membrane	1142:1164	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	3	6	theme	content	551:557	arg1	incorporation					524:536	the incorporation	520:536	the incorporation of sepiolite content into chitosan	520:571	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	1	7	theme	based	195:199	arg1	membranes					214:222	Cs/PVA/Sepolite based pH-sensitive membranes	179:222	Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process	179:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	5	8	theme	XRD	707:709	arg1	results					711:717	The obtained XRD results	694:717	The obtained XRD results	694:717	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	1	9	theme	membranes	214:222	arg1	Chitosan/PVA-blank					144:161	Chitosan/PVA-blank	144:161	Chitosan/PVA-blank	144:161	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	1	9	theme	membranes	214:222	arg1	series					169:174	a series	167:174	a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process	167:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	6	10	theme	due	1013:1015	arg1	sample					1006:1011	the Cs/PVA-blank sample	989:1011	the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix	989:1080	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	4	11	theme	membrane	649:656	arg1	spectra					623:629	the FTIR spectra	614:629	the FTIR spectra of the Cs/PVA/Sep membrane	614:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	6	12	theme	Cs/PVA-blank	993:1004	arg1	sample					1006:1011	the Cs/PVA-blank sample	989:1011	the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix	989:1080	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	8	13	theme	Cs/PVA/Sep-60	1333:1345	arg1	%					1346:1346	%	1346:1346	%	1346:1346	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	5	14	theme	Cs/PVA/Sep	747:756	arg1	membranes					758:766	Cs/PVA/Sep membranes	747:766	Cs/PVA/Sep membranes	747:766	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	1	15	theme	casting	241:247	arg1	process					249:255	a solution casting process	230:255	a solution casting process	230:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	8	16	theme	water	1278:1282	arg1	ability					1291:1297	The water uptake ability	1274:1297	The water uptake ability	1274:1297	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	7	17	theme	obtained	1087:1094	arg1	studies					1120:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	9	18	theme	lowest	1547:1552	arg1	values					1567:1572	the lowest water uptake values	1543:1572	the lowest water uptake values	1543:1572	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	6	19	with	interaction	1024:1034	arg1	matrix					1075:1080	the chitosan matrix	1062:1080	the chitosan matrix	1062:1080	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	10	20	dep	uptake	1616:1621	arg1	values					1625:1630	% values	1623:1630	the water uptake % values	1606:1630	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	2	21	theme	Cs/PVA/Sep	291:300	arg1	membranes					308:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes were investigated via SEM, FTIR, XRD, and TGA techniques.					
36642127	9	22	theme	uptake	1560:1565	arg1	values					1567:1572	the lowest water uptake values	1543:1572	the lowest water uptake values	1543:1572	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	5	23	theme	Cs/PVA-blank	787:798	arg1	membranes					800:808	the Cs/PVA-blank membranes	783:808	the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite	783:890	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	5	24	from	intercalation	823:835	arg1	spacing					867:873	the interlayer spacing	852:873	the interlayer spacing of the sepiolite	852:890	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	5	25	theme	interlayer	856:865	arg1	spacing					867:873	the interlayer spacing	852:873	the interlayer spacing of the sepiolite	852:890	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	6	26	theme	content	1049:1055	arg1	interaction					1024:1034	the interaction	1020:1034	the interaction of sepiolite content with the chitosan matrix	1020:1080	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	8	27	contain	had	1415:1417	arg2	value					1440:1444	maximum water uptake value	1419:1444	maximum water uptake value	1419:1444	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	8	27	contain	had	1415:1417	arg1	membrane					1406:1413	the Cs/PVA/-blank membrane	1388:1413	the Cs/PVA/-blank membrane	1388:1413	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	7	28	theme	acidic	1259:1264	arg1	medium					1266:1271	an acidic medium	1256:1271	an acidic medium	1256:1271	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	9	29	contain	had	1539:1541	arg1	those					1496:1500	those	1496:1500	those	1496:1500	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	9	29	contain	had	1539:1541	arg2	values					1567:1572	the lowest water uptake values	1543:1572	the lowest water uptake values	1543:1572	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	8	30	theme	maximum	1419:1425	arg1	uptake					1433:1438	maximum water uptake	1419:1438	maximum water uptake value	1419:1444	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	3	31	theme	Cs/PVA/Sep	395:404	arg1	membrane					412:419	Cs/PVA/Sep based membrane	395:419	Cs/PVA/Sep based membrane	395:419	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	8	32	theme	uptake	1433:1438	arg1	value					1440:1444	maximum water uptake value	1419:1444	maximum water uptake value	1419:1444	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	3	33	theme	hydrolytic	437:446	arg1	stability					448:456	the hydrolytic stability	433:456	the hydrolytic stability	433:456	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	7	34	theme	minimum	1236:1242	arg1	swelling					1244:1251	minimum swelling	1236:1251	minimum swelling in an acidic medium	1236:1271	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	0	35	theme	smart	15:19	arg1	Fabrication					41:51	Fabrication	41:51	Fabrication	41:51	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	35	theme	smart	15:19	arg1	behavior					71:78	pH-Responsive behavior	57:78	pH-Responsive behavior	57:78	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	35	theme	smart	15:19	arg1	composites					29:38	smart polymer composites	15:38	smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications	15:107	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	6	36	theme	TGA	906:908	arg1	results					910:916	The obtained TGA results	893:916	The obtained TGA results	893:916	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	4	37	theme	characteristic	578:591	arg1	band					593:596	The characteristic band	574:596	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane	574:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	7	38	theme	neutral	1208:1214	arg1	media					1216:1220	basic and neutral media	1198:1220	basic and neutral media	1198:1220	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	3	39	theme	membrane	412:419	arg1	results					384:390	The SEM results	376:390	The SEM results of Cs/PVA/Sep based membrane	376:419	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	10	40	theme	Sepolite	1578:1585	arg1	content					1587:1593	Sepolite content	1578:1593	Sepolite content	1578:1593	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	0	41	theme	pH-Responsive	57:69	arg1	behavior					71:78	pH-Responsive behavior	57:78	pH-Responsive behavior	57:78	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	41	theme	pH-Responsive	57:69	arg1	composites					29:38	smart polymer composites	15:38	smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications	15:107	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	8	42	theme	Cs/PVA/Sep-60	1465:1477	arg1	%					1478:1478	%	1478:1478	%	1478:1478	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	10	43	theme	polymer	1750:1756	arg1	formation					1758:1766	polymer formation	1750:1766	polymer formation	1750:1766	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	7	44	theme	basic	1198:1202	arg1	media					1216:1220	basic and neutral media	1198:1220	basic and neutral media	1198:1220	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	0	45	dep	composites	29:38	arg1	Fabrication					41:51	Fabrication	41:51	Fabrication	41:51	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	45	dep	composites	29:38	arg1	behavior					71:78	pH-Responsive behavior	57:78	pH-Responsive behavior	57:78	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	45	dep	composites	29:38	arg1	composites					29:38	smart polymer composites	15:38	smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications	15:107	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	2	46	theme	Cs/PVA-blank	274:285	arg1	membranes					308:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes were investigated via SEM, FTIR, XRD, and TGA techniques.					
36642127	4	47	theme	FTIR	618:621	arg1	spectra					623:629	the FTIR spectra	614:629	the FTIR spectra of the Cs/PVA/Sep membrane	614:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	4	48	theme	successful	672:681	arg1	synthesis					683:691	the successful synthesis	668:691	the successful synthesis	668:691	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	7	49	theme	enhanced	1176:1183	arg1	stability					1185:1193	enhanced stability	1176:1193	enhanced stability	1176:1193	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	10	50	from	weakness	1653:1660	arg1	H-bonding					1665:1673	H-bonding	1665:1673	H-bonding	1665:1673	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	6	51	theme	thermally	930:938	arg1	stability					940:948	higher thermally stability	923:948	higher thermally stability for Cs/PVA/Sep membrane	923:972	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	2	52	theme	TGA	360:362	arg1	techniques					364:373	TGA techniques	360:373	TGA techniques	360:373	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes were investigated via SEM, FTIR, XRD, and TGA techniques.					
36642127	3	53	theme	sepiolite	541:549	arg1	content					551:557	sepiolite content	541:557	sepiolite content	541:557	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	1	54	theme	Cs/PVA/Sepolite	179:193	arg1	membranes					214:222	Cs/PVA/Sepolite based pH-sensitive membranes	179:222	Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process	179:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	8	55	theme	uptake	1284:1289	arg1	ability					1291:1297	The water uptake ability	1274:1297	The water uptake ability	1274:1297	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	1	56	theme	pH-sensitive	201:212	arg1	membranes					214:222	Cs/PVA/Sepolite based pH-sensitive membranes	179:222	Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process	179:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	7	57	theme	swelling	1111:1118	arg1	studies					1120:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	7	58	from	swelling	1244:1251	arg1	medium					1266:1271	an acidic medium	1256:1271	an acidic medium	1256:1271	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	4	59	theme	Cs/PVA/Sep	638:647	arg1	membrane					649:656	the Cs/PVA/Sep membrane	634:656	the Cs/PVA/Sep membrane	634:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	7	60	theme	hydrolytic	1096:1105	arg1	studies					1120:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies	1083:1126	The obtained hydrolytic and swelling studies revealed that the Cs/PVA/Sep membrane displayed enhanced stability in basic and neutral media while showing minimum swelling in an acidic medium.					
36642127	2	61	theme	synthesized	262:272	arg1	membranes					308:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes were investigated via SEM, FTIR, XRD, and TGA techniques.					
36642127	9	62	theme	considerable	1509:1520	arg1	filler					1532:1537	filler	1532:1537	filler	1532:1537	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	9	62	theme	considerable	1509:1520	arg1	amount					1522:1527	a considerable amount	1507:1527	a considerable amount of filler	1507:1537	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	9	63	theme	filler	1532:1537	arg1	filler					1532:1537	filler	1532:1537	filler	1532:1537	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	9	63	theme	filler	1532:1537	arg1	amount					1522:1527	a considerable amount	1507:1527	a considerable amount of filler	1507:1537	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	5	64	theme	obtained	698:705	arg1	results					711:717	The obtained XRD results	694:717	The obtained XRD results	694:717	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	5	65	theme	higher	726:731	arg1	d-spacing					733:741	higher d-spacing	726:741	higher d-spacing for Cs/PVA/Sep membranes	726:766	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	8	66	theme	%	1346:1346	arg1	membrane					1348:1355	Cs/PVA/Sep-60% membrane	1333:1355	Cs/PVA/Sep-60% membrane	1333:1355	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	2	67	theme	based	302:306	arg1	membranes					308:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes	258:316	The synthesized Cs/PVA-blank and Cs/PVA/Sep based membranes were investigated via SEM, FTIR, XRD, and TGA techniques.					
36642127	9	68	theme	water	1554:1558	arg1	values					1567:1572	the lowest water uptake values	1543:1572	the lowest water uptake values	1543:1572	While those with a considerable amount of filler had the lowest water uptake values.					
36642127	6	69	theme	chitosan	1066:1073	arg1	matrix					1075:1080	the chitosan matrix	1062:1080	the chitosan matrix	1062:1080	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	0	70	theme	bio-medical	84:94	arg1	applications					96:107	bio-medical applications	84:107	bio-medical applications	84:107	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	6	71	theme	sepiolite	1039:1047	arg1	content					1049:1055	sepiolite content	1039:1055	sepiolite content	1039:1055	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	3	72	theme	SEM	380:382	arg1	results					384:390	The SEM results	376:390	The SEM results of Cs/PVA/Sep based membrane	376:419	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	8	73	theme	Cs/PVA/-blank	1392:1404	arg1	membrane					1406:1413	the Cs/PVA/-blank membrane	1388:1413	the Cs/PVA/-blank membrane	1388:1413	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	3	74	theme	basic	499:503	arg1	media					505:509	acidic and basic media	488:509	acidic and basic media owing to the incorporation of sepiolite content into chitosan	488:571	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	4	75	from	3741 cm-1	601:609	arg1	band					593:596	The characteristic band	574:596	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane	574:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36642127	1	76	theme	solution	232:239	arg1	process					249:255	a solution casting process	230:255	a solution casting process	230:255	This research aimed to synthesize Chitosan/PVA-blank and a series of Cs/PVA/Sepolite based pH-sensitive membranes using a solution casting process.					
36642127	5	77	theme	chitosan	840:847	arg1	intercalation					823:835	the intercalation	819:835	the intercalation of chitosan in the interlayer spacing of the sepiolite	819:890	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	3	78	theme	based	406:410	arg1	membrane					412:419	Cs/PVA/Sep based membrane	395:419	Cs/PVA/Sep based membrane	395:419	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	8	79	theme	water	1427:1431	arg1	uptake					1433:1438	maximum water uptake	1419:1438	maximum water uptake value	1419:1444	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	10	80	theme	hydrophilic	1679:1689	arg1	groups					1691:1696	hydrophilic groups	1679:1696	hydrophilic groups	1679:1696	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	0	81	theme	polymer	21:27	arg1	Fabrication					41:51	Fabrication	41:51	Fabrication	41:51	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	81	theme	polymer	21:27	arg1	behavior					71:78	pH-Responsive behavior	57:78	pH-Responsive behavior	57:78	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	0	81	theme	polymer	21:27	arg1	composites					29:38	smart polymer composites	15:38	smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications	15:107	Chitosan based smart polymer composites: Fabrication and pH-Responsive behavior for bio-medical applications.					
36642127	3	82	theme	acidic	488:493	arg1	media					505:509	acidic and basic media	488:509	acidic and basic media owing to the incorporation of sepiolite content into chitosan	488:571	The SEM results of Cs/PVA/Sep based membrane reveal that the hydrolytic stability and strength were improved in acidic and basic media owing to the incorporation of sepiolite content into chitosan.					
36642127	6	83	theme	obtained	897:904	arg1	results					910:916	The obtained TGA results	893:916	The obtained TGA results	893:916	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	8	84	theme	%	1478:1478	arg1	membrane					1480:1487	the Cs/PVA/Sep-60% membrane	1461:1487	the Cs/PVA/Sep-60% membrane	1461:1487	The water uptake ability was checked for Cs/PVA/-blank and Cs/PVA/Sep-60% membrane and the results exhibited that the Cs/PVA/-blank membrane had maximum water uptake value as compared to the Cs/PVA/Sep-60% membrane.					
36642127	10	85	theme	Sepolite	1727:1734	arg1	layers					1736:1741	Sepolite layers	1727:1741	Sepolite layers	1727:1741	As Sepolite content increased, the water uptake % values decreases because of weakness in H-bonding (of hydrophilic groups) and due to intercalation in Sepolite layers during polymer formation.					
36642127	5	86	theme	sepiolite	882:890	arg1	spacing					867:873	the interlayer spacing	852:873	the interlayer spacing of the sepiolite	852:890	The obtained XRD results showed higher d-spacing for Cs/PVA/Sep membranes as compared to the Cs/PVA-blank membranes owing to the intercalation of chitosan in the interlayer spacing of the sepiolite.					
36642127	6	87	dep	thermally	930:938	arg1	higher					923:928	higher	923:928	higher	923:928	The obtained TGA results show higher thermally stability for Cs/PVA/Sep membrane as compared to the Cs/PVA-blank sample due to the interaction of sepiolite content with the chitosan matrix.					
36642127	4	88	from	band	593:596	arg1	spectra					623:629	the FTIR spectra	614:629	the FTIR spectra of the Cs/PVA/Sep membrane	614:656	The characteristic band at 3741 cm-1 in the FTIR spectra of the Cs/PVA/Sep membrane confirmed the successful synthesis.					
36306549	9	0	theme	LPS	1047:1049	arg1	isolation					1051:1059	gtypical LPS isolation	1038:1059	gtypical LPS isolation	1038:1059	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	2	1	located	found	226:230	arg2	It					214:215	It	214:215	It	214:215	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	2	1	located	found	226:230	arg1	tissues					253:259	colorectal cancer tissues	235:259	colorectal cancer tissues	235:259	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	4	2	theme	F.	508:509	arg1	strains					497:503	three strains	491:503	three strains	491:503	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	11	3	dep	novel	1395:1399	arg1	novel					1395:1399	novel	1395:1399	novel	1395:1399	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	3	dep	novel	1395:1399	arg1	reported					1447:1454	reported	1447:1454	have not been previously reported	1422:1454	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	3	dep	novel	1395:1399	arg1	OPS					1364:1366	the OPS	1360:1366	the OPS from HM-995 and HM-997	1360:1389	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	4	dep	F.	1314:1315	arg1	nucleatum					1317:1325	F. nucleatum	1314:1325	F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1314:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	5	from	strain	1270:1275	arg1	Structure					1244:1252	Structure	1244:1252	Structure of the OPS from strain HM-994	1244:1282	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	5	from	strain	1270:1275	arg1	OPS					1261:1263	the OPS	1257:1263	the OPS from strain HM-994	1257:1282	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	6	dep	Structures	1346:1355	arg1	novel					1395:1399	novel	1395:1399	novel	1395:1399	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	6	dep	Structures	1346:1355	arg1	include					1460:1466	include	1460:1466	include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1460:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	6	dep	Structures	1346:1355	arg1	reported					1447:1454	reported	1447:1454	have not been previously reported	1422:1454	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	6	dep	Structures	1346:1355	arg1	knowledge					1412:1420	our knowledge	1408:1420	our knowledge	1408:1420	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	6	dep	Structures	1346:1355	arg1	OPS					1364:1366	the OPS	1360:1366	the OPS from HM-995 and HM-997	1360:1389	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	0	7	from	Structure	0:8	arg1	Fusobacterium					52:64	Fusobacterium	52:64	Fusobacterium	52:64	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	9	8	theme	standard	949:956	arg1	NMR					958:960	standard NMR	949:960	standard NMR	949:960	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	11	9	from	Structures	1346:1355	arg1	OPS					1305:1307	the OPS	1301:1307	the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1301:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	2	10	theme	pregnancy	280:288	arg1	stillbirths					328:338	stillbirths	328:338	stillbirths	328:338	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	2	10	theme	pregnancy	280:288	arg1	complications					290:302	pregnancy complications	280:302	pregnancy complications	280:302	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	2	10	theme	pregnancy	280:288	arg1	pre-term					315:322	pre-term	315:322	pre-term	315:322	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	12	11	from	strain	1726:1731	arg1	structures					1697:1706	LPS O-antigen structures	1683:1706	LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1683:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	12	12	dep	F.	1713:1714	arg1	nucleatum					1716:1724	F. nucleatum	1713:1724	F. nucleatum strain from both oral and cancerous origin	1713:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	9	13	theme	purification	1065:1076	arg1	methods					1078:1084	purification methods	1065:1084	purification methods	1065:1084	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	1	14	located	found	158:162	arg2	nucleatum					122:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	1	14	located	found	158:162	arg1	mouth					177:181	the human mouth	167:181	the human mouth where it causes periodontitis	167:211	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	1	14	located	found	158:162	arg2	bacterium					148:156	an anaerobic bacterium	135:156	an anaerobic bacterium found in the human mouth where it causes periodontitis	135:211	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	12	15	from	origin	1762:1767	arg1	strain					1726:1731	F. nucleatum strain	1713:1731	F. nucleatum strain from both oral and cancerous origin	1713:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	12	16	theme	oral	1743:1746	arg1	origin					1762:1767	both oral and cancerous origin	1738:1767	both oral and cancerous origin	1738:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	12	17	theme	cancerous	1752:1760	arg1	origin					1762:1767	both oral and cancerous origin	1738:1767	both oral and cancerous origin	1738:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	4	18	theme	cancerous	563:571	arg1	tissues					573:579	cancerous tissues	563:579	cancerous tissues	563:579	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	3	19	theme	surface	346:352	arg1	structures					354:363	Cell surface structures	341:363	Cell surface structures of the bacterium	341:380	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36306549	0	20	from	Fusobacterium	52:64	arg1	Structure					0:8	Structure	0:8	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum	0:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	0	20	from	Fusobacterium	52:64	arg1	O-antigens					36:45	the lipopolysaccharide O-antigens	13:45	the lipopolysaccharide O-antigens from Fusobacterium nucleatum	13:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	1	21	theme	human	171:175	arg1	mouth					177:181	the human mouth	167:181	the human mouth where it causes periodontitis	167:211	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	9	22	theme	gtypical	1038:1045	arg1	isolation					1051:1059	gtypical LPS isolation	1038:1059	gtypical LPS isolation	1038:1059	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	12	23	theme	LPS	1825:1827	arg1	structures					1839:1848	different LPS O-antigen structures	1815:1848	different LPS O-antigen structures elaborated by this organism	1815:1876	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	24	theme	observed	1478:1485	arg1	sugars					1496:1501	the often observed 6-deoxy- sugars	1468:1501	the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1468:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	25	theme	several	1512:1518	arg1	strains					1533:1539	several F. nucleatum strains	1512:1539	several F. nucleatum strains	1512:1539	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	26	theme	6-deoxy-	1487:1494	arg1	sugars					1496:1501	the often observed 6-deoxy- sugars	1468:1501	the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1468:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	9	27	theme	homo-	966:970	arg1	techniques					991:1000	homo- and hetero-nuclear techniques	966:1000	homo- and hetero-nuclear techniques	966:1000	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	12	28	theme	different	1815:1823	arg1	structures					1839:1848	different LPS O-antigen structures	1815:1848	different LPS O-antigen structures elaborated by this organism	1815:1876	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	29	theme	F.	1520:1521	arg1	strains					1533:1539	several F. nucleatum strains	1512:1539	several F. nucleatum strains	1512:1539	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	12	30	theme	increasing	1653:1662	arg1	variation					1664:1672	the ever increasing variation	1644:1672	the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1644:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	0	31	theme	lipopolysaccharide	17:34	arg1	O-antigens					36:45	the lipopolysaccharide O-antigens	13:45	the lipopolysaccharide O-antigens from Fusobacterium nucleatum	13:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	12	32	theme	structures	1839:1848	arg1	multitude					1802:1810	a multitude	1800:1810	a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts	1800:1930	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	33	theme	F.	1314:1315	arg1	Structures					1346:1355	F. nucleatum strain MJR 7757 B. Structures	1314:1355	F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1314:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	3	34	theme	bacterium	372:380	arg1	structures					354:363	Cell surface structures	341:363	Cell surface structures of the bacterium	341:380	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36306549	9	35	theme	hetero-nuclear	976:989	arg1	techniques					991:1000	homo- and hetero-nuclear techniques	966:1000	homo- and hetero-nuclear techniques	966:1000	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	12	36	theme	O-antigen	1829:1837	arg1	structures					1839:1848	different LPS O-antigen structures	1815:1848	different LPS O-antigen structures elaborated by this organism	1815:1876	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	37	from	modifications	1574:1586	arg1	strain					1602:1607	the HM-995 strain	1591:1607	the HM-995 strain	1591:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	12	38	theme	structural	1615:1624	arg1	knowledge					1626:1634	This structural knowledge	1610:1634	This structural knowledge	1610:1634	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	39	theme	7757 B.	1338:1344	arg1	Structures					1346:1355	F. nucleatum strain MJR 7757 B. Structures	1314:1355	F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1314:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	1	40	theme	Fusobacterium	108:120	arg1	nucleatum					122:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	1	40	theme	Fusobacterium	108:120	arg1	bacterium					148:156	an anaerobic bacterium	135:156	an anaerobic bacterium found in the human mouth where it causes periodontitis	135:211	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	11	41	from	Structure	1244:1252	arg1	strain					1270:1275	strain HM-994	1270:1282	strain HM-994	1270:1282	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	12	42	theme	F.	1713:1714	arg1	strain					1726:1731	F. nucleatum strain	1713:1731	F. nucleatum strain from both oral and cancerous origin	1713:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	10	43	theme	polymeric	1101:1109	arg1	material					1111:1118	polymeric material	1101:1118	polymeric material	1101:1118	In some cases polymeric material was further degraded in order to produce compounds that gave improved NMR spectra that were easier to be fully interpreted.					
36306549	0	44	theme	O-antigens	36:45	arg1	Structure					0:8	Structure	0:8	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum	0:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	4	45	dep	F.	508:509	arg1	nucleatum					511:519	F. nucleatum HM-994, HM-995, and HM-997	508:546	F. nucleatum HM-994, HM-995, and HM-997	508:546	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	45	dep	F.	508:509	arg1	HM-995					529:534	HM-995	529:534	HM-995	529:534	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	45	dep	F.	508:509	arg1	HM-997					541:546	HM-997	541:546	HM-997	541:546	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	45	dep	F.	508:509	arg1	HM-994					521:526	HM-994	521:526	HM-994	521:526	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	11	46	theme	strain	1327:1332	arg1	Structures					1346:1355	F. nucleatum strain MJR 7757 B. Structures	1314:1355	F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1314:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	4	47	theme	O-chain	474:480	arg1	structure					438:446	the structure	434:446	the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994	434:635	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	0	48	dep	Fusobacterium	52:64	arg1	nucleatum					66:74	Fusobacterium nucleatum	52:74	Fusobacterium nucleatum	52:74	Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997.					
36306549	11	49	from	HM-997	1384:1389	arg1	novel					1395:1399	novel	1395:1399	novel	1395:1399	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	49	from	HM-997	1384:1389	arg1	reported					1447:1454	reported	1447:1454	have not been previously reported	1422:1454	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	49	from	HM-997	1384:1389	arg1	OPS					1364:1366	the OPS	1360:1366	the OPS from HM-995 and HM-997	1360:1389	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	50	from	HM-995	1373:1378	arg1	novel					1395:1399	novel	1395:1399	novel	1395:1399	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	50	from	HM-995	1373:1378	arg1	reported					1447:1454	reported	1447:1454	have not been previously reported	1422:1454	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	50	from	HM-995	1373:1378	arg1	OPS					1364:1366	the OPS	1360:1366	the OPS from HM-995 and HM-997	1360:1389	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	4	51	theme	lipopolysaccharide	455:472	arg1	OPS					483:485	OPS	483:485	OPS	483:485	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	51	theme	lipopolysaccharide	455:472	arg1	O-chain					474:480	the lipopolysaccharide O-chain	451:480	the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues	451:579	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	11	52	dep	F.	1520:1521	arg1	nucleatum					1523:1531	F. nucleatum	1520:1531	several F. nucleatum strains	1512:1539	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	12	53	theme	O-antigen	1687:1695	arg1	structures					1697:1706	LPS O-antigen structures	1683:1706	LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1683:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	10	54	theme	NMR	1190:1192	arg1	spectra					1194:1200	improved NMR spectra	1181:1200	improved NMR spectra that were easier to be fully interpreted	1181:1241	In some cases polymeric material was further degraded in order to produce compounds that gave improved NMR spectra that were easier to be fully interpreted.					
36306549	12	55	theme	LPS	1683:1685	arg1	structures					1697:1706	LPS O-antigen structures	1683:1706	LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1683:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	11	56	theme	MJR	1334:1336	arg1	Structures					1346:1355	F. nucleatum strain MJR 7757 B. Structures	1314:1355	F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1314:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	10	57	theme	improved	1181:1188	arg1	spectra					1194:1200	improved NMR spectra	1181:1200	improved NMR spectra that were easier to be fully interpreted	1181:1241	In some cases polymeric material was further degraded in order to produce compounds that gave improved NMR spectra that were easier to be fully interpreted.					
36306549	11	58	theme	OPS	1261:1263	arg1	Structure					1244:1252	Structure	1244:1252	Structure of the OPS from strain HM-994	1244:1282	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	9	59	theme	chemical	1011:1018	arg1	methods					1020:1026	chemical methods	1011:1026	chemical methods	1011:1026	The structures were determined using standard NMR (2D homo- and hetero-nuclear techniques), MS and chemical methods following gtypical LPS isolation and purification methods.					
36306549	4	60	attach	isolated	549:556	arg2	strains					497:503	three strains	491:503	three strains	491:503	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	60	attach	isolated	549:556	arg1	tissues					573:579	cancerous tissues	563:579	cancerous tissues	563:579	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	11	61	located	found	1503:1507	arg1	butyrate					1545:1552	butyrate	1545:1552	butyrate	1545:1552	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	61	located	found	1503:1507	arg2	sugars					1496:1501	the often observed 6-deoxy- sugars	1468:1501	the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1468:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	11	61	located	found	1503:1507	arg1	strains					1533:1539	several F. nucleatum strains	1512:1539	several F. nucleatum strains	1512:1539	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	4	62	theme	-3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N-	582:628	arg1	HM-994					630:635	-3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994	582:635	the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994	434:635	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	12	63	theme	serotyping	1913:1922	arg1	efforts					1924:1930	any serotyping efforts	1909:1930	any serotyping efforts	1909:1930	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	12	64	located	found	1674:1678	arg2	variation					1664:1672	the ever increasing variation	1644:1672	the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1644:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	12	64	located	found	1674:1678	arg1	structures					1697:1706	LPS O-antigen structures	1683:1706	LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin	1683:1767	This structural knowledge adds to the ever increasing variation found in LPS O-antigen structures from F. nucleatum strain from both oral and cancerous origin and suggests that there may be a multitude of different LPS O-antigen structures elaborated by this organism that may present challenges to any serotyping efforts.					
36306549	1	65	theme	anaerobic	138:146	arg1	nucleatum					122:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum	108:130	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	1	65	theme	anaerobic	138:146	arg1	bacterium					148:156	an anaerobic bacterium	135:156	an anaerobic bacterium found in the human mouth where it causes periodontitis	135:211	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36306549	11	66	theme	acetate	1566:1572	arg1	modifications					1574:1586	acetate modifications	1566:1586	the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain	1468:1607	Structure of the OPS from strain HM-994 was identical to the OPS from F. nucleatum strain MJR 7757 B. Structures of the OPS from HM-995 and HM-997 are novel and to our knowledge have not been previously reported and include the often observed 6-deoxy- sugars found in several F. nucleatum strains and butyrate rather than acetate modifications in the HM-995 strain.					
36306549	2	67	theme	cancer	246:251	arg1	tissues					253:259	colorectal cancer tissues	235:259	colorectal cancer tissues	235:259	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	3	68	theme	Cell	341:344	arg1	structures					354:363	Cell surface structures	341:363	Cell surface structures of the bacterium	341:380	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36306549	4	69	theme	strains	497:503	arg1	OPS					483:485	OPS	483:485	OPS	483:485	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	4	69	theme	strains	497:503	arg1	O-chain					474:480	the lipopolysaccharide O-chain	451:480	the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues	451:579	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	2	70	theme	colorectal	235:244	arg1	tissues					253:259	colorectal cancer tissues	235:259	colorectal cancer tissues	235:259	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36306549	4	71	dep	structure	438:446	arg1	HM-994					630:635	-3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994	582:635	the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994	434:635	Here we report the structure of the lipopolysaccharide O-chain (OPS) of three strains of F. nucleatum HM-994, HM-995, and HM-997, isolated from cancerous tissues: -3-β-D-ManNAc4Lac-4-β-D-Glc6OAc-3-β-D-FucNAc4N- HM-994.					
36306549	8	72	theme	pyranose	897:904	arg1	form					906:909	the pyranose form	893:909	the pyranose form	893:909	All monosaccharides are in the pyranose form.					
36040460	3	0	theme	water	523:527	arg1	capacity					540:547	appropriate water absorption capacity	511:547	appropriate water absorption capacity	511:547	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	3	1	theme	appropriate	511:521	arg1	capacity					540:547	appropriate water absorption capacity	511:547	appropriate water absorption capacity	511:547	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	1	2	theme	complications	272:284	arg1	delay					235:239	the delay	231:239	the delay of wound healing and secondary complications	231:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	4	3	theme	LTCF-5	654:659	arg1	film					661:664	the LTCF-5 film	650:664	the LTCF-5 film	650:664	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	3	theme	LTCF-5	654:659	arg1	higher					810:815	higher	810:815	higher	810:815	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	6	4	theme	defect	1519:1524	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	5	theme	skin	188:191	arg1	infections					193:202	human skin infections	182:202	human skin infections	182:202	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	6	6	theme	full-thickness	1494:1507	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	6	7	dep	in	1526:1527	arg1	vivo					1529:1532	vivo	1529:1532	vivo	1529:1532	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	5	8	theme	sustained	1021:1029	arg1	release					1031:1037	slow and sustained release	1012:1037	slow and sustained release of Ag+ with good strength and biodegradability	1012:1084	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	3	9	theme	moist	570:574	arg1	environment					576:586	a moist environment	568:586	a moist environment for wound healing	568:604	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	6	10	theme	aureus	1478:1483	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	3	11	contain	had	466:468	arg2	capacity					540:547	appropriate water absorption capacity	511:547	appropriate water absorption capacity	511:547	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	3	11	contain	had	466:468	arg1	films					460:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	3	11	contain	had	466:468	arg2	transparency					493:504	high transparency	488:504	high transparency	488:504	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	3	11	contain	had	466:468	arg2	flexibility					475:485	good flexibility	470:485	good flexibility	470:485	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	6	12	theme	carboxymethyl	1397:1409	arg1	film					1418:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	4	13	theme	reported	835:842	arg1	dressings					858:866	the reported biodegradable dressings	831:866	the reported biodegradable dressings	831:866	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	6	14	theme	antibacterial	1568:1580	arg1	activity					1582:1589	its long-lasting antibacterial activity	1551:1589	its long-lasting antibacterial activity	1551:1589	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	6	15	theme	good	1592:1595	arg1	biocompatibility					1597:1612	good biocompatibility	1592:1612	good biocompatibility	1592:1612	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	6	16	theme	moist	1660:1664	arg1	environment					1666:1676	a moist environment	1658:1676	a moist environment	1658:1676	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	7	17	dep	loaded	1688:1693	arg1	Ag+					1684:1686	Ag+	1684:1686	Ag+	1684:1686	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	5	18	theme	antibacterial	1248:1260	arg1	activity					1262:1269	good antibacterial activity	1243:1269	good antibacterial activity	1243:1269	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	19	theme	slow	1012:1015	arg1	release					1031:1037	slow and sustained release	1012:1037	slow and sustained release of Ag+ with good strength and biodegradability	1012:1084	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	7	20	theme	excellent	1726:1734	arg1	films					1716:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	7	20	theme	excellent	1726:1734	arg1	candidates					1736:1745	excellent candidates	1726:1745	excellent candidates for infected wound healing	1726:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	0	21	theme	antibacterial	73:85	arg1	activity					87:94	long-lasting antibacterial activity	60:94	long-lasting antibacterial activity for infected wound healing	60:121	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	6	22	theme	loaded	1390:1395	arg1	film					1418:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	23	theme	main	167:170	arg1	causes					172:177	the main causes	163:177	the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications	163:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	4	24	theme	best	681:684	arg1	strength					697:704	mechanical strength	686:704	the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films	677:800	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	25	from	MPa	743:745	arg1	state					758:762	the wet state	750:762	the wet state	750:762	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	25	from	MPa	743:745	arg1	state					728:732	the dry state	720:732	the dry state	720:732	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	7	26	theme	carboxymethyl	1695:1707	arg1	films					1716:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	7	26	theme	carboxymethyl	1695:1707	arg1	candidates					1736:1745	excellent candidates	1726:1745	excellent candidates for infected wound healing	1726:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	0	27	theme	wound	109:113	arg1	healing					115:121	infected wound healing	100:121	infected wound healing	100:121	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	5	28	theme	hydrofiber	935:944	arg1	dressing					946:953	the commercial hydrofiber dressing	920:953	the commercial hydrofiber dressing with silver (AQUACEL®)	920:976	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	3	29	theme	chitin	453:458	arg1	films					460:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	6	30	theme	exudate	1615:1621	arg1	absorption					1623:1632	exudate absorption	1615:1632	exudate absorption	1615:1632	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	6	31	theme	chitin	1411:1416	arg1	film					1418:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	4	32	theme	dry	724:726	arg1	state					728:732	the dry state	720:732	the dry state	720:732	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	5	33	with	Ag+	1042:1044	arg1	strength					1056:1063	good strength	1051:1063	good strength	1051:1063	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	33	with	Ag+	1042:1044	arg1	biodegradability					1069:1084	biodegradability	1069:1084	biodegradability	1069:1084	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	0	34	theme	biodegradable	14:26	arg1	films					49:53	biodegradable carboxymethyl chitin films	14:53	biodegradable carboxymethyl chitin films	14:53	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	1	35	theme	Bacteria-related	124:139	arg1	infections					141:150	Bacteria-related infections	124:150	Bacteria-related infections	124:150	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	5	36	theme	bacteriostatic	1288:1301	arg1	rates					1303:1307	almost 100% bacteriostatic rates	1276:1307	almost 100% bacteriostatic rates	1276:1307	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	0	37	theme	chitin	42:47	arg1	films					49:53	biodegradable carboxymethyl chitin films	14:53	biodegradable carboxymethyl chitin films	14:53	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	5	38	theme	excellent	1101:1109	arg1	activity					1138:1145	excellent long-lasting antibacterial activity	1101:1145	excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli	1101:1189	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	4	39	theme	carboxymethyl	775:787	arg1	films					796:800	the carboxymethyl chitin films	771:800	the carboxymethyl chitin films	771:800	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	5	40	theme	antibacterial	1124:1136	arg1	activity					1138:1145	excellent long-lasting antibacterial activity	1101:1145	excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli	1101:1189	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	41	dep	rates	1303:1307	arg1	%					1286:1286	%	1286:1286	%	1286:1286	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	2	42	theme	biodegradable	319:331	arg1	films					333:337	novel biodegradable films	313:337	novel biodegradable films based on thermosensitive carboxymethyl chitin	313:383	In this work, a series of novel biodegradable films based on thermosensitive carboxymethyl chitin were prepared without using any crosslinkers.					
36040460	5	43	dep	%	1286:1286	arg1	100					1283:1285	100	1283:1285	100	1283:1285	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	4	44	theme	silver	611:616	arg1	ions					618:621	The silver ions	607:621	The silver ions (Ag+)	607:627	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	44	theme	silver	611:616	arg1	Ag+					624:626	Ag+	624:626	Ag+	624:626	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	5	45	theme	buffered	1336:1343	arg1	saline					1345:1350	phosphate buffered saline	1326:1350	phosphate buffered saline	1326:1350	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	3	46	theme	absorption	529:538	arg1	capacity					540:547	appropriate water absorption capacity	511:547	appropriate water absorption capacity	511:547	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	6	47	theme	wound	1456:1460	arg1	healing					1462:1468	infected cutaneous wound healing	1437:1468	infected cutaneous wound healing	1437:1468	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	5	48	theme	obvious	1199:1205	arg1	cytotoxicity					1207:1218	obvious cytotoxicity	1199:1218	obvious cytotoxicity	1199:1218	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	2	49	theme	thermosensitive	348:362	arg1	chitin					378:383	thermosensitive carboxymethyl chitin	348:383	thermosensitive carboxymethyl chitin	348:383	In this work, a series of novel biodegradable films based on thermosensitive carboxymethyl chitin were prepared without using any crosslinkers.					
36040460	6	50	theme	infected	1437:1444	arg1	healing					1462:1468	infected cutaneous wound healing	1437:1468	infected cutaneous wound healing	1437:1468	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	51	theme	healing	250:256	arg1	delay					235:239	the delay	231:239	the delay of wound healing and secondary complications	231:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	4	52	contain	had	673:675	arg2	strength					697:704	mechanical strength	686:704	the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films	677:800	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	52	contain	had	673:675	arg1	film					661:664	the LTCF-5 film	650:664	the LTCF-5 film	650:664	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	52	contain	had	673:675	arg1	higher					810:815	higher	810:815	higher	810:815	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	1	53	theme	secondary	262:270	arg1	complications					272:284	secondary complications	262:284	secondary complications	262:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	6	54	theme	in	1526:1527	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	55	theme	human	182:186	arg1	infections					193:202	human skin infections	182:202	human skin infections	182:202	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	4	56	theme	chitin	789:794	arg1	films					796:800	the carboxymethyl chitin films	771:800	the carboxymethyl chitin films	771:800	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	6	57	theme	cutaneous	1509:1517	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	58	theme	infections	193:202	arg1	causes					172:177	the main causes	163:177	the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications	163:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	7	59	theme	wound	1760:1764	arg1	healing					1766:1772	infected wound healing	1751:1772	infected wound healing	1751:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	6	60	theme	infected	1485:1492	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	5	61	with	dressing	946:953	arg1	AQUACEL®					968:975	AQUACEL®	968:975	AQUACEL®	968:975	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	61	with	dressing	946:953	arg1	silver					960:965	silver	960:965	silver (AQUACEL®)	960:976	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	6	62	theme	S.	1475:1476	arg1	model					1534:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	a S. aureus infected full-thickness cutaneous defect in vivo model	1473:1538	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	4	63	theme	available	885:893	arg1	dressings					895:903	commercially available dressings	872:903	commercially available dressings	872:903	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	5	64	theme	Ag+	1042:1044	arg1	release					1031:1037	slow and sustained release	1012:1037	slow and sustained release of Ag+ with good strength and biodegradability	1012:1084	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	3	65	theme	wound	592:596	arg1	healing					598:604	wound healing	592:604	wound healing	592:604	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	4	66	theme	mechanical	686:695	arg1	strength					697:704	mechanical strength	686:704	the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films	677:800	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	5	67	theme	good	1243:1246	arg1	activity					1262:1269	good antibacterial activity	1243:1269	good antibacterial activity	1243:1269	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	68	contain	possessed	1233:1241	arg2	activity					1262:1269	good antibacterial activity	1243:1269	good antibacterial activity	1243:1269	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	68	contain	possessed	1233:1241	arg1	cytotoxicity					1207:1218	obvious cytotoxicity	1199:1218	obvious cytotoxicity	1199:1218	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	6	69	theme	long-lasting	1555:1566	arg1	activity					1582:1589	its long-lasting antibacterial activity	1551:1589	its long-lasting antibacterial activity	1551:1589	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	7	70	theme	infected	1751:1758	arg1	healing					1766:1772	infected wound healing	1751:1772	infected wound healing	1751:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	4	71	theme	biodegradable	844:856	arg1	dressings					858:866	the reported biodegradable dressings	831:866	the reported biodegradable dressings	831:866	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	3	72	theme	high	488:491	arg1	transparency					493:504	high transparency	488:504	high transparency	488:504	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	0	73	theme	infected	100:107	arg1	healing					115:121	infected wound healing	100:121	infected wound healing	100:121	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	1	74	theme	causes	172:177	arg1	one					156:158	one	156:158	one	156:158	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	1	74	theme	causes	172:177	arg1	causes					172:177	the main causes	163:177	the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications	163:284	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36040460	5	75	theme	commercial	924:933	arg1	dressing					946:953	the commercial hydrofiber dressing	920:953	the commercial hydrofiber dressing with silver (AQUACEL®)	920:976	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	7	76	theme	chitin	1709:1714	arg1	films					1716:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	7	76	theme	chitin	1709:1714	arg1	candidates					1736:1745	excellent candidates	1726:1745	excellent candidates for infected wound healing	1726:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	5	77	theme	good	1051:1054	arg1	strength					1056:1063	good strength	1051:1063	good strength	1051:1063	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	7	78	theme	loaded	1688:1693	arg1	films					1716:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films	1679:1720	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	7	78	theme	loaded	1688:1693	arg1	candidates					1736:1745	excellent candidates	1726:1745	excellent candidates for infected wound healing	1726:1772	Thus Ag+ loaded carboxymethyl chitin films are excellent candidates for infected wound healing.					
36040460	3	79	theme	carboxymethyl	439:451	arg1	films					460:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films	431:464	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	0	80	theme	carboxymethyl	28:40	arg1	films					49:53	biodegradable carboxymethyl chitin films	14:53	biodegradable carboxymethyl chitin films	14:53	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	4	81	from	MPa	713:715	arg1	state					758:762	the wet state	750:762	the wet state	750:762	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	81	from	MPa	713:715	arg1	state					728:732	the dry state	720:732	the dry state	720:732	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	82	dep	strength	697:704	arg1	MPa					713:715	56.39 MPa	707:715	56.39 MPa in the dry state	707:732	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	4	82	dep	strength	697:704	arg1	MPa					743:745	0.66 MPa	738:745	0.66 MPa in the wet state	738:762	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	6	83	theme	Ag+	1386:1388	arg1	film					1418:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	the Ag+ loaded carboxymethyl chitin film	1382:1421	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	3	84	theme	good	470:473	arg1	flexibility					475:485	good flexibility	470:485	good flexibility	470:485	All the carboxymethyl chitin films had good flexibility, high transparency, and appropriate water absorption capacity, and could provide a moist environment for wound healing.					
36040460	0	85	theme	long-lasting	60:71	arg1	activity					87:94	long-lasting antibacterial activity	60:94	long-lasting antibacterial activity for infected wound healing	60:121	Silver loaded biodegradable carboxymethyl chitin films with long-lasting antibacterial activity for infected wound healing.					
36040460	5	86	theme	long-lasting	1111:1122	arg1	activity					1138:1145	excellent long-lasting antibacterial activity	1101:1145	excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli	1101:1189	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	5	87	theme	composite	983:991	arg1	film					993:996	the composite film	979:996	the composite film	979:996	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	2	88	theme	films	333:337	arg1	series					303:308	a series	301:308	a series of novel biodegradable films based on thermosensitive carboxymethyl chitin	301:383	In this work, a series of novel biodegradable films based on thermosensitive carboxymethyl chitin were prepared without using any crosslinkers.					
36040460	5	89	theme	phosphate	1326:1334	arg1	saline					1345:1350	phosphate buffered saline	1326:1350	phosphate buffered saline	1326:1350	Compared with the commercial hydrofiber dressing with silver (AQUACEL®), the composite film could provide slow and sustained release of Ag+ with good strength and biodegradability, and displayed excellent long-lasting antibacterial activity in vitro against both S. aureus and E. coli without obvious cytotoxicity, which still possessed good antibacterial activity with almost 100% bacteriostatic rates after soaking in phosphate buffered saline for 7 days.					
36040460	2	90	theme	novel	313:317	arg1	films					333:337	novel biodegradable films	313:337	novel biodegradable films based on thermosensitive carboxymethyl chitin	313:383	In this work, a series of novel biodegradable films based on thermosensitive carboxymethyl chitin were prepared without using any crosslinkers.					
36040460	4	91	theme	wet	754:756	arg1	state					758:762	the wet state	750:762	the wet state	750:762	The silver ions (Ag+) were incorporated on the LTCF-5 film, which had the best mechanical strength (56.39 MPa in the dry state and 0.66 MPa in the wet state) among the carboxymethyl chitin films and was higher than those of the reported biodegradable dressings and commercially available dressings.					
36040460	2	92	theme	carboxymethyl	364:376	arg1	chitin					378:383	thermosensitive carboxymethyl chitin	348:383	thermosensitive carboxymethyl chitin	348:383	In this work, a series of novel biodegradable films based on thermosensitive carboxymethyl chitin were prepared without using any crosslinkers.					
36040460	6	93	theme	cutaneous	1446:1454	arg1	healing					1462:1468	infected cutaneous wound healing	1437:1468	infected cutaneous wound healing	1437:1468	More importantly, the Ag+ loaded carboxymethyl chitin film could promote infected cutaneous wound healing in a S. aureus infected full-thickness cutaneous defect in vivo model because of its long-lasting antibacterial activity, good biocompatibility, exudate absorption and ability to maintain a moist environment.					
36040460	1	94	theme	wound	244:248	arg1	healing					250:256	wound healing	244:256	wound healing	244:256	Bacteria-related infections are one of the main causes of human skin infections, which are associated with the delay of wound healing and secondary complications.					
36184165	4	0	theme	thermal	892:898	arg1	diffusivity					900:910	thermal diffusivity	892:910	thermal diffusivity	892:910	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	5	1	theme	CNF	1154:1156	arg1	surface					1158:1164	the TEMPO-oxidized CNF surface	1135:1164	the TEMPO-oxidized CNF surface	1135:1164	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	4	2	with	film	819:822	arg1	groups					857:862	proton-neutralized carboxyl groups	829:862	proton-neutralized carboxyl groups	829:862	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	3	link	biomass-derived	246:260	arg1	materials					276:284	biomass-derived heat-transfer materials	246:284	biomass-derived heat-transfer materials	246:284	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	0	4	theme	metal	95:99	arg1	ions					101:104	multivalent metal ions	83:104	multivalent metal ions	83:104	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	3	5	theme	film	699:702	arg1	diffusivity					680:690	the in-plane thermal diffusivity	659:690	the in-plane thermal diffusivity of the film	659:702	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	3	5	theme	film	699:702	arg1	proportional					717:728	proportional	717:728	proportional	717:728	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	4	6	theme	various	933:939	arg1	ions					947:950	various metal ions	933:950	various metal ions	933:950	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	7	theme	biomass-derived	246:260	arg1	materials					276:284	biomass-derived heat-transfer materials	246:284	biomass-derived heat-transfer materials	246:284	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	0	8	theme	multivalent	83:93	arg1	ions					101:104	multivalent metal ions	83:104	multivalent metal ions	83:104	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	4	9	theme	diffusivity	900:910	arg1	level					883:887	the highest level	871:887	the highest level of thermal diffusivity among the films with various metal ions	871:950	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	4	10	with	films	922:926	arg1	ions					947:950	various metal ions	933:950	various metal ions	933:950	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	11	theme	heat-transfer	262:274	arg1	materials					276:284	biomass-derived heat-transfer materials	246:284	biomass-derived heat-transfer materials	246:284	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	2	12	theme	thermal	531:537	arg1	diffusivities					539:551	their thermal diffusivities	525:551	their thermal diffusivities in the dry state	525:568	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	3	13	theme	ionic	737:741	arg1	radius					743:748	the ionic radius	733:748	the ionic radius	733:748	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	1	14	theme	cellulose	171:179	arg1	CNF					193:195	CNF	193:195	CNF	193:195	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	1	14	theme	cellulose	171:179	arg1	nanofibril					181:190	cellulose nanofibril	171:190	cellulose nanofibril (CNF) films	171:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	0	15	theme	ions	101:104	arg1	addition					71:78	addition	71:78	addition of multivalent metal ions	71:104	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	5	16	theme	TEMPO-oxidized	1139:1152	arg1	surface					1158:1164	the TEMPO-oxidized CNF surface	1135:1164	the TEMPO-oxidized CNF surface	1135:1164	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	2	17	theme	diffusivity	632:642	arg1	tunability					606:615	the tunability	602:615	the tunability of the thermal diffusivity	602:642	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	1	18	dep	principles	119:128	arg1	tune					133:136	tune	133:136	to tune the heat-transport properties of cellulose nanofibril (CNF) films	130:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	1	19	theme	nanofibril	181:190	arg1	films					198:202	cellulose nanofibril (CNF) films	171:202	cellulose nanofibril (CNF) films	171:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	2	20	with	films	413:417	arg1	groups					440:445	surface carboxy groups	424:445	surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	424:510	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	2	21	theme	thermal	624:630	arg1	diffusivity					632:642	the thermal diffusivity	620:642	the thermal diffusivity	620:642	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	5	22	theme	dynamics	963:970	arg1	simulations					972:982	Molecular dynamics simulations	953:982	Molecular dynamics simulations	953:982	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	2	23	theme	multivalent	383:393	arg1	ions					401:404	various multivalent metal ions	375:404	various multivalent metal ions	375:404	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	1	24	theme	materials	276:284	arg1	development					231:241	the development	227:241	the development of biomass-derived heat-transfer materials	227:284	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	3	25	theme	thermal	672:678	arg1	diffusivity					680:690	the in-plane thermal diffusivity	659:690	the in-plane thermal diffusivity of the film	659:702	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	3	25	theme	thermal	672:678	arg1	proportional					717:728	proportional	717:728	proportional	717:728	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	2	26	theme	various	375:381	arg1	ions					401:404	various multivalent metal ions	375:404	various multivalent metal ions	375:404	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	2	27	theme	carboxy	432:438	arg1	groups					440:445	surface carboxy groups	424:445	surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	424:510	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	5	28	theme	closest	1068:1074	arg1	distance					1076:1083	the closest distance	1064:1083	the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface	1064:1164	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	2	29	theme	surface	424:430	arg1	groups					440:445	surface carboxy groups	424:445	surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	424:510	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	4	30	theme	metal	941:945	arg1	ions					947:950	various metal ions	933:950	various metal ions	933:950	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	2	31	theme	2,2,6,6-tetramethylpiperidine-1-oxyl	457:492	arg1	oxidation					502:510	2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	457:510	2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	457:510	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	1	32	theme	films	198:202	arg1	properties					157:166	the heat-transport properties	138:166	the heat-transport properties of cellulose nanofibril (CNF) films	138:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	2	33	theme	dry	560:562	arg1	state					564:568	the dry state	556:568	the dry state	556:568	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	5	34	theme	carboxylate	1108:1118	arg1	atom					1127:1130	the cation and carboxylate oxygen atom	1093:1130	atom	1127:1130	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	4	35	theme	proton-neutralized	829:846	arg1	groups					857:862	proton-neutralized carboxyl groups	829:862	proton-neutralized carboxyl groups	829:862	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	2	36	theme	CNF	409:411	arg1	films					413:417	CNF films	409:417	CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation	409:510	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	0	37	theme	diffusivity	26:36	arg1	Tunability					0:9	Tunability	0:9	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.	0:105	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	3	38	theme	Pauling	783:789	arg1	electro-negativity					791:808	the Pauling electro-negativity	779:808	the Pauling electro-negativity	779:808	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	5	39	theme	oxygen	1120:1125	arg1	atom					1127:1130	the cation and carboxylate oxygen atom	1093:1130	atom	1127:1130	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	0	40	theme	thermal	18:24	arg1	diffusivity					26:36	the thermal diffusivity	14:36	the thermal diffusivity of cellulose nanofibril films	14:66	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	0	41	theme	nanofibril	51:60	arg1	films					62:66	cellulose nanofibril films	41:66	cellulose nanofibril films	41:66	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	5	42	theme	spatial	1003:1009	arg1	distribution					1011:1022	the spatial distribution	999:1022	the spatial distribution of the introduced ions	999:1045	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	4	43	theme	highest	875:881	arg1	level					883:887	the highest level	871:887	the highest level of thermal diffusivity among the films with various metal ions	871:950	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	44	theme	Discovering	107:117	arg1	principles					119:128	Discovering principles	107:128	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films	107:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	0	45	theme	cellulose	41:49	arg1	films					62:66	cellulose nanofibril films	41:66	cellulose nanofibril films	41:66	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	1	46	theme	petroleum-based	315:329	arg1	composites					339:348	petroleum-based polymer composites	315:348	petroleum-based polymer composites	315:348	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	4	47	theme	carboxyl	848:855	arg1	groups					857:862	proton-neutralized carboxyl groups	829:862	proton-neutralized carboxyl groups	829:862	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	48	theme	polymer	331:337	arg1	composites					339:348	petroleum-based polymer composites	315:348	petroleum-based polymer composites	315:348	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36184165	2	49	theme	original	576:583	arg1	method					585:590	an original method	573:590	an original method to verify the tunability of the thermal diffusivity	573:642	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	3	50	theme	in-plane	663:670	arg1	diffusivity					680:690	the in-plane thermal diffusivity	659:690	the in-plane thermal diffusivity of the film	659:702	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	3	50	theme	in-plane	663:670	arg1	proportional					717:728	proportional	717:728	proportional	717:728	We found that the in-plane thermal diffusivity of the film is inversely proportional to the ionic radius and directly proportional to the Pauling electro-negativity.					
36184165	5	51	theme	introduced	1031:1040	arg1	ions					1042:1045	the introduced ions	1027:1045	the introduced ions	1027:1045	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	5	52	theme	Molecular	953:961	arg1	simulations					972:982	Molecular dynamics simulations	953:982	Molecular dynamics simulations	953:982	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	2	53	from	diffusivities	539:551	arg1	state					564:568	the dry state	556:568	the dry state	556:568	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	5	54	theme	ions	1042:1045	arg1	distribution					1011:1022	the spatial distribution	999:1022	the spatial distribution of the introduced ions	999:1045	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	2	55	theme	metal	395:399	arg1	ions					401:404	various multivalent metal ions	375:404	various multivalent metal ions	375:404	In this study, we added various multivalent metal ions to CNF films with surface carboxy groups formed by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) oxidation and measured their thermal diffusivities in the dry state by an original method to verify the tunability of the thermal diffusivity.					
36184165	0	56	theme	films	62:66	arg1	diffusivity					26:36	the thermal diffusivity	14:36	the thermal diffusivity of cellulose nanofibril films	14:66	Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions.					
36184165	5	57	theme	surface	1158:1164	arg1	cation					1097:1102	the cation and carboxylate oxygen atom	1093:1130	cation	1097:1102	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	5	57	theme	surface	1158:1164	arg1	atom					1127:1130	the cation and carboxylate oxygen atom	1093:1130	atom	1127:1130	Molecular dynamics simulations clarified that the spatial distribution of the introduced ions is determined by the closest distance between the cation and carboxylate oxygen atom of the TEMPO-oxidized CNF surface.					
36184165	4	58	theme	CNF	815:817	arg1	film					819:822	The CNF film	811:822	The CNF film with proton-neutralized carboxyl groups	811:862	The CNF film with proton-neutralized carboxyl groups showed the highest level of thermal diffusivity among the films with various metal ions.					
36184165	1	59	theme	heat-transport	142:155	arg1	properties					157:166	the heat-transport properties	138:166	the heat-transport properties of cellulose nanofibril (CNF) films	138:202	Discovering principles to tune the heat-transport properties of cellulose nanofibril (CNF) films will open the door for the development of biomass-derived heat-transfer materials and break away from existing petroleum-based polymer composites.					
36435466	9	0	theme	electron	1457:1464	arg1	microscopy					1466:1475	the scanning electron microscopy	1444:1475	the scanning electron microscopy	1444:1475	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	6	1	theme	coagulation	1109:1119	arg1	bath					1121:1124	coagulation bath	1109:1124	coagulation bath	1109:1124	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	1	2	theme	ionic	174:178	arg1	liquids					180:186	ionic liquids	174:186	ionic liquids	174:186	Fabricating regenerated cellulose fibers using ionic liquids is a novel and green technology.					
36435466	9	3	dep	results	1477:1483	arg1	revealed					1485:1492	revealed	1485:1492	results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics	1477:1651	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	0	4	theme	mechanical	72:81	arg1	properties					83:92	mechanical properties	72:92	mechanical properties	72:92	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	9	5	dep	more	1438:1441	arg1	's					1435:1436	's	1435:1436	's	1435:1436	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	8	6	theme	regenerated	1281:1291	arg1	fibers					1293:1298	regenerated fibers	1281:1298	regenerated fibers	1281:1298	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	5	7	theme	mechanical	835:844	arg1	properties					846:855	mechanical properties	835:855	mechanical properties	835:855	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	6	8	theme	spinning	1087:1094	arg1	solution					1096:1103	spinning solution	1087:1103	spinning solution	1087:1103	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	0	9	theme	regenerated	97:107	arg1	fibers					119:124	regenerated cellulose fibers	97:124	regenerated cellulose fibers	97:124	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	0	10	from	Effects	0:6	arg1	orientation					56:66	orientation	56:66	orientation	56:66	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	0	10	from	Effects	0:6	arg1	properties					83:92	mechanical properties	72:92	mechanical properties	72:92	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	0	10	from	Effects	0:6	arg1	crystallinity					41:53	crystallinity	41:53	crystallinity	41:53	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	5	11	theme	fibers	778:783	arg1	properties					752:761	the properties	748:761	the properties of regenerated fibers	748:783	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	3	12	from	conditions	399:408	arg1	study					346:350	The study	342:350	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning,	342:493	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	12	from	conditions	399:408	arg1	necessary					498:506	necessary	498:506	necessary	498:506	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	9	13	theme	fabrics	1645:1651	arg1	application					1622:1632	the application	1618:1632	the application of textile fabrics	1618:1651	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	4	14	theme	1-ethyl-3-methylimidazolium	606:632	arg1	[Emim					652:656	[Emim	652:656	[Emim	652:656	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	4	14	theme	1-ethyl-3-methylimidazolium	606:632	arg1	diethylphosphate					634:649	1-ethyl-3-methylimidazolium diethylphosphate	606:649	1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP)	606:661	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	3	15	theme	fiber	371:375	arg1	mechanisms					385:394	the regenerated fiber forming mechanisms	355:394	the regenerated fiber forming mechanisms	355:394	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	8	16	from	content	1340:1346	arg1	bath					1363:1366	coagulation bath	1351:1366	coagulation bath	1351:1366	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	8	17	theme	fibers	1293:1298	arg1	crystallinity					1248:1260	crystallinity	1248:1260	crystallinity	1248:1260	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	8	17	theme	fibers	1293:1298	arg1	orientation					1266:1276	orientation	1266:1276	orientation	1266:1276	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	9	18	theme	scanning	1448:1455	arg1	microscopy					1466:1475	the scanning electron microscopy	1444:1475	the scanning electron microscopy	1444:1475	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	2	19	theme	macroscopic	296:306	arg1	properties					308:317	the macroscopic properties	292:317	the macroscopic properties of regenerated fibers	292:339	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	8	20	theme	ethanol	1373:1379	arg1	content					1381:1387	ethanol content	1373:1387	ethanol content	1373:1387	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	0	21	theme	cellulose	109:117	arg1	fibers					119:124	regenerated cellulose fibers	97:124	regenerated cellulose fibers	97:124	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	8	22	dep	crystallinity	1248:1260	arg1	the					1244:1246	the	1244:1246	the	1244:1246	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	5	23	theme	regenerated	860:870	arg1	fibers					872:877	regenerated fibers	860:877	regenerated fibers	860:877	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	0	24	theme	fibers	119:124	arg1	orientation					56:66	orientation	56:66	orientation	56:66	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	0	24	theme	fibers	119:124	arg1	properties					83:92	mechanical properties	72:92	mechanical properties	72:92	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	0	24	theme	fibers	119:124	arg1	crystallinity					41:53	crystallinity	41:53	crystallinity	41:53	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	5	25	theme	internal	811:818	arg1	structures					820:829	internal structures	811:829	internal structures	811:829	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	5	26	dep	structures	820:829	arg1	the					807:809	the	807:809	the	807:809	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	1	27	theme	novel	193:197	arg1	technology					209:218	a novel and green technology	191:218	a novel and green technology	191:218	Fabricating regenerated cellulose fibers using ionic liquids is a novel and green technology.					
36435466	3	28	theme	fiber	422:426	arg1	processes					437:445	fiber spinning processes	422:445	fiber spinning processes	422:445	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	6	29	theme	diffusion	1063:1071	arg1	rates					1073:1077	the different diffusion rates	1049:1077	the different diffusion rates between spinning solution and coagulation bath	1049:1124	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	3	30	from	study	346:350	arg1	process					466:472	the process	462:472	the process of dry-wet spinning	462:492	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	30	from	study	346:350	arg1	conditions					399:408	conditions	399:408	conditions relevant to fiber spinning processes	399:445	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	5	31	theme	regenerated	766:776	arg1	fibers					778:783	regenerated fibers	766:783	regenerated fibers	766:783	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	6	32	theme	regenerated	926:936	arg1	fibers					948:953	regenerated cellulose fibers	926:953	regenerated cellulose fibers	926:953	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	0	33	theme	conditions	23:32	arg1	Effects					0:6	Effects	0:6	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.	0:125	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	6	34	theme	different	1053:1061	arg1	rates					1073:1077	the different diffusion rates	1049:1077	the different diffusion rates between spinning solution and coagulation bath	1049:1124	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	8	35	theme	decreased	1319:1327	arg1	content					1340:1346	the decreased of ethanol content	1315:1346	the decreased of ethanol content in coagulation bath	1315:1366	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	2	36	theme	fibers	334:339	arg1	properties					308:317	the macroscopic properties	292:317	the macroscopic properties of regenerated fibers	292:339	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	1	37	theme	green	203:207	arg1	technology					209:218	a novel and green technology	191:218	a novel and green technology	191:218	Fabricating regenerated cellulose fibers using ionic liquids is a novel and green technology.					
36435466	0	38	theme	coagulating	11:21	arg1	conditions					23:32	coagulating conditions	11:32	coagulating conditions	11:32	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	4	39	theme	pulp	591:594	arg1	meal					596:599	wood pulp meal	586:599	wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP)	586:661	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	6	40	theme	cellulose	938:946	arg1	fibers					948:953	regenerated cellulose fibers	926:953	regenerated cellulose fibers	926:953	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	2	41	theme	regenerated	322:332	arg1	fibers					334:339	regenerated fibers	322:339	regenerated fibers	322:339	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	6	42	theme	internal	997:1004	arg1	structure					1006:1014	their internal structure	991:1014	their internal structure	991:1014	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	5	43	theme	fibers	872:877	arg1	structures					820:829	internal structures	811:829	internal structures	811:829	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	5	43	theme	fibers	872:877	arg1	properties					846:855	mechanical properties	835:855	mechanical properties	835:855	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	8	44	theme	ethanol	1332:1338	arg1	content					1340:1346	the decreased of ethanol content	1315:1346	the decreased of ethanol content in coagulation bath	1315:1366	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	4	45	theme	wood	586:589	arg1	meal					596:599	wood pulp meal	586:599	wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP)	586:661	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	4	46	theme	coagulation	677:687	arg1	compositions					694:705	various coagulation bath compositions	669:705	various coagulation bath compositions	669:705	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	2	47	theme	fibers	255:260	arg1	changes					232:238	Structural changes	221:238	Structural changes of regenerated fibers during forming process	221:283	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	3	48	theme	dry-wet	477:483	arg1	spinning					485:492	dry-wet spinning	477:492	dry-wet spinning	477:492	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	8	49	theme	coagulation	1351:1361	arg1	bath					1363:1366	coagulation bath	1351:1366	coagulation bath	1351:1366	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	4	50	theme	cellulose	550:558	arg1	fibers					560:565	regenerated cellulose fibers	538:565	regenerated cellulose fibers	538:565	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	8	51	theme	of	1329:1330	arg1	content					1340:1346	the decreased of ethanol content	1315:1346	the decreased of ethanol content in coagulation bath	1315:1366	In addition, both the crystallinity and orientation of regenerated fibers increased with the decreased of ethanol content in coagulation bath when ethanol content >70 %, while the elongation was reversed.					
36435466	3	52	from	mechanisms	385:394	arg1	process					466:472	the process	462:472	the process of dry-wet spinning	462:492	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	52	from	mechanisms	385:394	arg1	conditions					399:408	conditions	399:408	conditions relevant to fiber spinning processes	399:445	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	0	53	dep	crystallinity	41:53	arg1	the					37:39	the	37:39	the	37:39	Effects of coagulating conditions on the crystallinity, orientation and mechanical properties of regenerated cellulose fibers.					
36435466	3	54	theme	spinning	485:492	arg1	process					466:472	the process	462:472	the process of dry-wet spinning	462:492	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	55	theme	spinning	428:435	arg1	processes					437:445	fiber spinning processes	422:445	fiber spinning processes	422:445	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	56	theme	mechanisms	385:394	arg1	study					346:350	The study	342:350	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning,	342:493	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	56	theme	mechanisms	385:394	arg1	necessary					498:506	necessary	498:506	necessary	498:506	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	6	57	theme	due	1042:1044	arg1	structure					1006:1014	their internal structure	991:1014	their internal structure	991:1014	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	6	58	theme	mechanical	1020:1029	arg1	properties					1031:1040	mechanical properties	1020:1040	mechanical properties	1020:1040	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	3	59	theme	forming	377:383	arg1	mechanisms					385:394	the regenerated fiber forming mechanisms	355:394	the regenerated fiber forming mechanisms	355:394	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	2	60	theme	Structural	221:230	arg1	changes					232:238	Structural changes	221:238	Structural changes of regenerated fibers during forming process	221:283	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	9	61	contain	have	1594:1597	arg1	fibers					1587:1592	the regenerated fibers	1571:1592	the regenerated fibers	1571:1592	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	9	61	contain	have	1594:1597	arg2	potential					1605:1613	great potential	1599:1613	great potential	1599:1613	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	4	62	with	meal	596:599	arg1	[Emim					652:656	[Emim	652:656	[Emim	652:656	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	4	62	with	meal	596:599	arg1	diethylphosphate					634:649	1-ethyl-3-methylimidazolium diethylphosphate	606:649	1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP)	606:661	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	5	63	theme	coagulating	722:732	arg1	conditions					734:743	coagulating conditions	722:743	coagulating conditions	722:743	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	6	64	from	differences	976:986	arg1	properties					1031:1040	mechanical properties	1020:1040	mechanical properties	1020:1040	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	6	64	from	differences	976:986	arg1	structure					1006:1014	their internal structure	991:1014	their internal structure	991:1014	The results indicated that regenerated cellulose fibers eventually developed differences in their internal structure and mechanical properties due to the different diffusion rates between spinning solution and coagulation bath.					
36435466	2	65	theme	regenerated	243:253	arg1	fibers					255:260	regenerated fibers	243:260	regenerated fibers	243:260	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	1	66	theme	regenerated	139:149	arg1	fibers					161:166	regenerated cellulose fibers	139:166	regenerated cellulose fibers using ionic liquids	139:186	Fabricating regenerated cellulose fibers using ionic liquids is a novel and green technology.					
36435466	5	67	theme	conditions	734:743	arg1	effect					712:717	The effect	708:717	The effect of coagulating conditions on the properties of regenerated fibers	708:783	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	4	68	dep	[Emim	652:656	arg1	DEP					658:660	DEP	658:660	DEP	658:660	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	9	69	theme	regenerated	1503:1513	arg1	homogeneous					1547:1557	homogeneous	1547:1557	homogeneous	1547:1557	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	9	69	theme	regenerated	1503:1513	arg1	surfaces					1533:1540	the regenerated cellulose fibers' surfaces	1499:1540	the regenerated cellulose fibers' surfaces	1499:1540	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	1	70	theme	cellulose	151:159	arg1	fibers					161:166	regenerated cellulose fibers	139:166	regenerated cellulose fibers using ionic liquids	139:186	Fabricating regenerated cellulose fibers using ionic liquids is a novel and green technology.					
36435466	9	71	theme	great	1599:1603	arg1	potential					1605:1613	great potential	1599:1613	great potential	1599:1613	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	4	72	theme	various	669:675	arg1	compositions					694:705	various coagulation bath compositions	669:705	various coagulation bath compositions	669:705	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	2	73	theme	forming	269:275	arg1	process					277:283	forming process	269:283	forming process	269:283	Structural changes of regenerated fibers during forming process affect the macroscopic properties of regenerated fibers.					
36435466	9	74	theme	regenerated	1575:1585	arg1	fibers					1587:1592	the regenerated fibers	1571:1592	the regenerated fibers	1571:1592	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	4	75	theme	bath	689:692	arg1	compositions					694:705	various coagulation bath compositions	669:705	various coagulation bath compositions	669:705	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36435466	5	76	from	effect	712:717	arg1	properties					752:761	the properties	748:761	the properties of regenerated fibers	748:783	The effect of coagulating conditions on the properties of regenerated fibers was investigated, and the internal structures and mechanical properties of regenerated fibers were characterized.					
36435466	3	77	theme	regenerated	359:369	arg1	mechanisms					385:394	the regenerated fiber forming mechanisms	355:394	the regenerated fiber forming mechanisms	355:394	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	78	theme	relevant	410:417	arg1	conditions					399:408	conditions	399:408	conditions relevant to fiber spinning processes	399:445	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	79	from	process	466:472	arg1	study					346:350	The study	342:350	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning,	342:493	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	3	79	from	process	466:472	arg1	necessary					498:506	necessary	498:506	necessary	498:506	The study of the regenerated fiber forming mechanisms in conditions relevant to fiber spinning processes, especially in the process of dry-wet spinning, is necessary and meaningful.					
36435466	9	80	theme	textile	1637:1643	arg1	fabrics					1645:1651	textile fabrics	1637:1651	textile fabrics	1637:1651	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	9	81	theme	cellulose	1515:1523	arg1	homogeneous					1547:1557	homogeneous	1547:1557	homogeneous	1547:1557	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	9	81	theme	cellulose	1515:1523	arg1	surfaces					1533:1540	the regenerated cellulose fibers' surfaces	1499:1540	the regenerated cellulose fibers' surfaces	1499:1540	What's more, the scanning electron microscopy results revealed that the regenerated cellulose fibers' surfaces were homogeneous, indicating the regenerated fibers have great potential in the application of textile fabrics.					
36435466	4	82	theme	regenerated	538:548	arg1	fibers					560:565	regenerated cellulose fibers	538:565	regenerated cellulose fibers	538:565	In this work, regenerated cellulose fibers were prepared from wood pulp meal with 1-ethyl-3-methylimidazolium diethylphosphate ([Emim]DEP) under various coagulation bath compositions.					
36563814	2	0	theme	bulbifer	425:432	arg1	flour					434:438	the A. bulbifer flour	418:438	the A. bulbifer flour	418:438	However, the gel formed by KGM from the A. bulbifer flour is easily browning during the alkali-induced process and the mechanism underlying them is still unclear.					
36563814	1	1	theme	glucomannan	307:317	arg1	content					325:331	high konjac glucomannan (KGM) content	295:331	high konjac glucomannan (KGM) content	295:331	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	4	2	theme	amino	768:772	arg1	acids					774:778	amino acids	768:778	amino acids	768:778	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	6	3	theme	gel	1244:1246	arg1	browning					1248:1255	KGM gel browning	1240:1255	KGM gel browning	1240:1255	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	5	4	theme	flour	1126:1130	arg1	changes					1111:1117	color changes	1105:1117	color changes of KGM flour during deacetylation	1105:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	5	theme	reproductive	224:235	arg1	coefficient					237:247	high reproductive coefficient	219:247	high reproductive coefficient	219:247	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	2	6	theme	A.	422:423	arg1	flour					434:438	the A. bulbifer flour	418:438	the A. bulbifer flour	418:438	However, the gel formed by KGM from the A. bulbifer flour is easily browning during the alkali-induced process and the mechanism underlying them is still unclear.					
36563814	3	7	theme	color	621:625	arg1	parameters					627:636	color parameters	621:636	color parameters	621:636	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	5	8	theme	flavones	967:974	arg1	reasons					1093:1099	the main reasons	1084:1099	the main reasons for color changes of KGM flour during deacetylation	1084:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	8	theme	flavones	967:974	arg1	polymerization					933:946	polymerization	933:946	polymerization	933:946	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	8	theme	flavones	967:974	arg1	oxidation					920:928	oxidation	920:928	oxidation	920:928	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	9	theme	coefficient	237:247	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	9	theme	coefficient	237:247	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	0	10	theme	deacetylation	84:96	arg1	reaction					98:105	the deacetylation reaction	80:105	the deacetylation reaction	80:105	Evaluation of the composition of konjac glucomannan on the color changes during the deacetylation reaction.					
36563814	1	11	theme	KGM	320:322	arg1	content					325:331	high konjac glucomannan (KGM) content	295:331	high konjac glucomannan (KGM) content	295:331	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	12	from	reaction	1028:1035	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	4	13	theme	L	706:706	arg1	*					707:707	The L*	702:707	The L*	702:707	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	6	14	theme	food	1309:1312	arg1	industries					1324:1333	food and other industries	1309:1333	food and other industries	1309:1333	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	5	15	theme	main	1088:1091	arg1	reasons					1093:1099	the main reasons	1084:1099	the main reasons for color changes of KGM flour during deacetylation	1084:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	15	theme	main	1088:1091	arg1	oxidation					920:928	oxidation	920:928	oxidation	920:928	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	15	theme	main	1088:1091	arg1	polymerization					933:946	polymerization	933:946	polymerization	933:946	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	4	16	theme	KGM	841:843	arg1	degree					831:836	deacetylation degree	817:836	deacetylation degree of KGM	817:843	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	5	17	dep	oxidation	920:928	arg1	the					916:918	the	916:918	the	916:918	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	18	theme	short	250:254	arg1	cycle					263:267	short growth cycle	250:267	short growth cycle	250:267	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	19	theme	content	325:331	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	19	theme	content	325:331	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	4	20	theme	reducing	747:754	arg1	sugars					756:761	reducing sugars	747:761	reducing sugars	747:761	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	6	21	theme	other	1318:1322	arg1	industries					1324:1333	food and other industries	1309:1333	food and other industries	1309:1333	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	1	22	theme	Amorphophallus	148:161	arg1	bulbifer					163:170	the Amorphophallus bulbifer	144:170	the Amorphophallus bulbifer (A. bulbifer)	144:184	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	22	theme	Amorphophallus	148:161	arg1	bulbifer					176:183	bulbifer	176:183	bulbifer	176:183	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	0	23	theme	glucomannan	40:50	arg1	composition					18:28	the composition	14:28	the composition of konjac glucomannan	14:50	Evaluation of the composition of konjac glucomannan on the color changes during the deacetylation reaction.					
36563814	5	24	from	polyphenols	951:961	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	6	25	theme	KGM	1302:1304	arg1	range					1293:1297	the application range	1277:1297	the application range of KGM in food and other industries	1277:1333	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	6	26	theme	application	1281:1291	arg1	range					1293:1297	the application range	1277:1297	the application range of KGM in food and other industries	1277:1333	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	5	27	from	circumstances	988:1000	arg1	reasons					1093:1099	the main reasons	1084:1099	the main reasons for color changes of KGM flour during deacetylation	1084:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	27	from	circumstances	988:1000	arg1	polymerization					933:946	polymerization	933:946	polymerization	933:946	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	27	from	circumstances	988:1000	arg1	oxidation					920:928	oxidation	920:928	oxidation	920:928	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	28	theme	climate	337:343	arg1	adaption					345:352	climate adaption	337:352	climate adaption	337:352	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	6	29	theme	browning	1248:1255	arg1	inhibition					1226:1235	the inhibition	1222:1235	the inhibition of KGM gel browning	1222:1255	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	5	30	theme	alkaline	979:986	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	3	31	theme	parameters	627:636	arg1	changes					594:600	the changes	590:600	the changes of composition and color parameters of KGM	590:643	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	5	32	theme	carbonyl	1011:1018	arg1	reaction					1028:1035	the carbonyl ammonia reaction	1007:1035	the carbonyl ammonia reaction between reducing sugars and amino acids	1007:1075	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	33	theme	growth	256:261	arg1	cycle					263:267	short growth cycle	250:267	short growth cycle	250:267	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	34	theme	ammonia	1020:1026	arg1	reaction					1028:1035	the carbonyl ammonia reaction	1007:1035	the carbonyl ammonia reaction between reducing sugars and amino acids	1007:1075	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	3	35	theme	composition	605:615	arg1	changes					594:600	the changes	590:600	the changes of composition and color parameters of KGM	590:643	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	6	36	from	range	1293:1297	arg1	industries					1324:1333	food and other industries	1309:1333	food and other industries	1309:1333	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	0	37	theme	composition	18:28	arg1	Evaluation					0:9	Evaluation	0:9	Evaluation of the composition of konjac glucomannan on the color	0:63	Evaluation of the composition of konjac glucomannan on the color changes during the deacetylation reaction.					
36563814	1	38	theme	cycle	263:267	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	38	theme	cycle	263:267	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	4	39	theme	deacetylation	817:829	arg1	degree					831:836	deacetylation degree	817:836	deacetylation degree of KGM	817:843	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	5	40	from	oxidation	920:928	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	6	41	theme	theoretical	1200:1210	arg1	basis					1212:1216	the theoretical basis	1196:1216	the theoretical basis for the inhibition of KGM gel browning	1196:1255	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	1	42	theme	adaption	345:352	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	42	theme	adaption	345:352	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	0	43	theme	konjac	33:38	arg1	glucomannan					40:50	konjac glucomannan	33:50	konjac glucomannan	33:50	Evaluation of the composition of konjac glucomannan on the color changes during the deacetylation reaction.					
36563814	1	44	theme	high	270:273	arg1	resistance					283:292	high disease resistance	270:292	high disease resistance	270:292	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	45	theme	polyphenols	951:961	arg1	reasons					1093:1099	the main reasons	1084:1099	the main reasons for color changes of KGM flour during deacetylation	1084:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	45	theme	polyphenols	951:961	arg1	polymerization					933:946	polymerization	933:946	polymerization	933:946	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	45	theme	polyphenols	951:961	arg1	oxidation					920:928	oxidation	920:928	oxidation	920:928	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	4	46	theme	degree	831:836	arg1	increase					805:812	the increase	801:812	the increase of deacetylation degree of KGM	801:843	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	4	47	theme	browning	863:870	arg1	index					872:876	browning index	863:876	browning index	863:876	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	1	48	theme	disease	275:281	arg1	resistance					283:292	high disease resistance	270:292	high disease resistance	270:292	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	2	49	theme	alkali-induced	470:483	arg1	process					485:491	the alkali-induced process	466:491	the alkali-induced process	466:491	However, the gel formed by KGM from the A. bulbifer flour is easily browning during the alkali-induced process and the mechanism underlying them is still unclear.					
36563814	1	50	theme	hot	357:359	arg1	conditions					370:379	hot or humid conditions	357:379	hot or humid conditions	357:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	51	theme	several	190:196	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	51	theme	several	190:196	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	52	theme	resistance	283:292	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	52	theme	resistance	283:292	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	53	theme	amino	1065:1069	arg1	acids					1071:1075	amino acids	1065:1075	amino acids	1065:1075	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	0	54	from	Evaluation	0:9	arg1	color					59:63	the color	55:63	the color	55:63	Evaluation of the composition of konjac glucomannan on the color changes during the deacetylation reaction.					
36563814	5	55	theme	reducing	1045:1052	arg1	sugars					1054:1059	reducing sugars	1045:1059	reducing sugars	1045:1059	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	56	theme	humid	364:368	arg1	conditions					370:379	hot or humid conditions	357:379	hot or humid conditions	357:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	4	57	theme	total	729:733	arg1	flavonoids					735:744	total flavonoids	729:744	total flavonoids	729:744	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	5	58	theme	reaction	1028:1035	arg1	reasons					1093:1099	the main reasons	1084:1099	the main reasons for color changes of KGM flour during deacetylation	1084:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	58	theme	reaction	1028:1035	arg1	polymerization					933:946	polymerization	933:946	polymerization	933:946	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	58	theme	reaction	1028:1035	arg1	oxidation					920:928	oxidation	920:928	oxidation	920:928	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	3	59	theme	browning	569:576	arg1	mechanisms					578:587	the browning mechanisms	565:587	the browning mechanisms	565:587	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	1	60	theme	high	295:298	arg1	content					325:331	high konjac glucomannan (KGM) content	295:331	high konjac glucomannan (KGM) content	295:331	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	61	contain	has	186:188	arg2	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	61	contain	has	186:188	arg1	bulbifer					176:183	bulbifer	176:183	bulbifer	176:183	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	61	contain	has	186:188	arg1	bulbifer					163:170	the Amorphophallus bulbifer	144:170	the Amorphophallus bulbifer (A. bulbifer)	144:184	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	61	contain	has	186:188	arg2	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	62	theme	unique	198:203	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	62	theme	unique	198:203	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	6	63	theme	KGM	1240:1242	arg1	browning					1248:1255	KGM gel browning	1240:1255	KGM gel browning	1240:1255	Hence, this study was expected to provide the theoretical basis for the inhibition of KGM gel browning and further broaden the application range of KGM in food and other industries.					
36563814	4	64	theme	h	710:710	arg1	*					711:711	h*	710:711	h*	710:711	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	1	65	theme	superior	119:126	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	65	theme	superior	119:126	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	66	from	flavones	967:974	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	5	67	theme	color	1105:1109	arg1	changes					1111:1117	color changes	1105:1117	color changes of KGM flour during deacetylation	1105:1151	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	4	68	theme	total	714:718	arg1	phenols					720:726	total phenols	714:726	total phenols	714:726	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	1	69	theme	konjac	128:133	arg1	variety					135:141	a newly superior konjac variety	111:141	a newly superior konjac variety	111:141	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	1	69	theme	konjac	128:133	arg1	advantages					205:214	several unique advantages	190:214	several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions	190:379	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	5	70	from	polymerization	933:946	arg1	circumstances					988:1000	alkaline circumstances	979:1000	alkaline circumstances	979:1000	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	71	theme	konjac	300:305	arg1	content					325:331	high konjac glucomannan (KGM) content	295:331	high konjac glucomannan (KGM) content	295:331	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36563814	3	72	theme	KGM	641:643	arg1	composition					605:615	composition	605:615	composition	605:615	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	3	72	theme	KGM	641:643	arg1	parameters					627:636	color parameters	621:636	color parameters	621:636	In order to explore the browning mechanisms, the changes of composition and color parameters of KGM were investigated during deacetylation in this research.					
36563814	4	73	theme	a	851:851	arg1	*					852:852	a*	851:852	a*	851:852	The L*, h*, total phenols, total flavonoids, reducing sugars, and amino acids decreased along with the increase of deacetylation degree of KGM while a*, ΔЕ, and browning index increased.					
36563814	5	74	theme	KGM	1122:1124	arg1	flour					1126:1130	KGM flour	1122:1130	KGM flour	1122:1130	The results indicated that the oxidation or polymerization of polyphenols and flavones in alkaline circumstances, and the carbonyl ammonia reaction between reducing sugars and amino acids may be the main reasons for color changes of KGM flour during deacetylation.					
36563814	1	75	theme	high	219:222	arg1	coefficient					237:247	high reproductive coefficient	219:247	high reproductive coefficient	219:247	As a newly superior konjac variety, the Amorphophallus bulbifer (A. bulbifer) has several unique advantages of high reproductive coefficient, short growth cycle, high disease resistance, high konjac glucomannan (KGM) content and climate adaption to hot or humid conditions.					
36358068	8	0	theme	starch	1132:1137	arg1	digestion					1139:1147	starch digestion	1132:1147	starch digestion	1132:1147	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	5	1	theme	starch-protein	595:608	arg1	interaction					610:620	starch-protein interaction	595:620	starch-protein interaction	595:620	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	1	2	theme	cellulose	136:144	arg1	stripping					123:131	the gradual stripping	111:131	the gradual stripping of cellulose and protein in the milling process	111:179	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	5	3	dep	Fourier	540:546	arg1	transform					548:556	transform	548:556	transform infrared (FTIR) analysis	548:581	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	4	4	with	microstructure	445:458	arg1	degree					490:495	higher milling degree	475:495	higher milling degree after cooking	475:509	Accordingly, the microstructure of quinoa with higher milling degree after cooking was more uniform and denser.					
36358068	8	5	theme	confocal	987:994	arg1	microscope					1011:1020	the confocal laser scanning microscope	983:1020	the confocal laser scanning microscope	983:1020	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	7	6	theme	starch	929:934	arg1	patterns					910:917	three digestion patterns	894:917	three digestion patterns of quinoa starch during milling	894:949	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	7	7	theme	starch	831:836	arg1	digestograms					838:849	the starch digestograms	827:849	the starch digestograms	827:849	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	8	8	theme	laser	996:1000	arg1	microscope					1011:1020	the confocal laser scanning microscope	983:1020	the confocal laser scanning microscope	983:1020	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	0	9	from	Effect	0:5	arg1	digestion					48:56	in vitro digestion	39:56	in vitro digestion of starch during the milling process of quinoa	39:103	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	8	10	theme	microscope	1011:1020	arg1	results					972:978	The results	968:978	The results of the confocal laser scanning microscope	968:1020	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	5	11	theme	infrared	558:565	arg1	analysis					574:581	infrared (FTIR) analysis	558:581	infrared (FTIR) analysis	558:581	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	0	12	theme	milling	79:85	arg1	process					87:93	the milling process	75:93	the milling process of quinoa	75:103	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	8	13	theme	scanning	1002:1009	arg1	microscope					1011:1020	the confocal laser scanning microscope	983:1020	the confocal laser scanning microscope	983:1020	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	1	14	from	stripping	123:131	arg1	process					173:179	the milling process	161:179	the milling process	161:179	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	2	15	theme	0.23	308:311	arg1	%					303:303	%	303:303	%	303:303	In particular, milling reduced the content of saponins from 5.06% to 0.23%.					
36358068	1	16	theme	gradual	115:121	arg1	stripping					123:131	the gradual stripping	111:131	the gradual stripping of cellulose and protein in the milling process	111:179	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	0	17	theme	quinoa	98:103	arg1	process					87:93	the milling process	75:93	the milling process of quinoa	75:103	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	6	18	theme	digestibility	754:766	arg1	rate					768:771	the digestibility rate	750:771	the digestibility rate	750:771	The digestibility of protein and starch was interrelated, and the digestibility rate increased with the raising milling degree.					
36358068	1	19	theme	protein	150:156	arg1	stripping					123:131	the gradual stripping	111:131	the gradual stripping of cellulose and protein in the milling process	111:179	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	0	20	theme	in	39:40	arg1	digestion					48:56	in vitro digestion	39:56	in vitro digestion of starch during the milling process of quinoa	39:103	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	7	21	theme	digestion	900:908	arg1	patterns					910:917	three digestion patterns	894:917	three digestion patterns of quinoa starch during milling	894:949	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	3	22	theme	gelatinization	386:399	arg1	enthalpy					401:408	the gelatinization enthalpy	382:408	the gelatinization enthalpy of quinoa starch	382:425	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	8	23	theme	physical	1038:1045	arg1	barrier					1047:1053	the physical barrier	1034:1053	the physical barrier composed of protein matrix coated starch and starch-protein complex	1034:1121	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	3	24	theme	swelling	337:344	arg1	power					346:350	the swelling power	333:350	the swelling power of quinoa flour	333:366	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	1	25	theme	milling	165:171	arg1	process					173:179	the milling process	161:179	the milling process	161:179	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	0	26	theme	interaction	24:34	arg1	Effect					0:5	Effect	0:5	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.	0:104	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	7	27	theme	quinoa	922:927	arg1	starch					929:934	quinoa starch	922:934	quinoa starch	922:934	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	2	28	dep	%	303:303	arg1	to					305:306	to	305:306	to	305:306	In particular, milling reduced the content of saponins from 5.06% to 0.23%.					
36358068	3	29	theme	quinoa	413:418	arg1	starch					420:425	quinoa starch	413:425	quinoa starch	413:425	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	0	30	theme	compositional	10:22	arg1	interaction					24:34	compositional interaction	10:34	compositional interaction	10:34	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	3	31	theme	starch	420:425	arg1	enthalpy					401:408	the gelatinization enthalpy	382:408	the gelatinization enthalpy of quinoa starch	382:425	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	3	32	theme	quinoa	355:360	arg1	flour					362:366	quinoa flour	355:366	quinoa flour	355:366	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	5	33	theme	quinoa	673:678	arg1	starch					680:685	quinoa starch	673:685	quinoa starch	673:685	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	7	34	theme	digestion	869:877	arg1	model					887:891	the digestion kinetic model	865:891	the digestion kinetic model	865:891	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	3	35	theme	flour	362:366	arg1	power					346:350	the swelling power	333:350	the swelling power of quinoa flour	333:366	Milling increased the swelling power of quinoa flour but decreased the gelatinization enthalpy of quinoa starch.					
36358068	4	36	theme	milling	482:488	arg1	degree					490:495	higher milling degree	475:495	higher milling degree after cooking	475:509	Accordingly, the microstructure of quinoa with higher milling degree after cooking was more uniform and denser.					
36358068	5	37	theme	starch	680:685	arg1	structure					660:668	the ordered structure	648:668	the ordered structure of quinoa starch	648:685	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	4	38	theme	higher	475:480	arg1	degree					490:495	higher milling degree	475:495	higher milling degree after cooking	475:509	Accordingly, the microstructure of quinoa with higher milling degree after cooking was more uniform and denser.					
36358068	8	39	theme	coated	1082:1087	arg1	starch					1089:1094	protein matrix coated starch	1067:1094	protein matrix coated starch	1067:1094	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	0	40	dep	in	39:40	arg1	vitro					42:46	vitro	42:46	vitro	42:46	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	6	41	theme	starch	721:726	arg1	digestibility					692:704	The digestibility	688:704	The digestibility of protein and starch	688:726	The digestibility of protein and starch was interrelated, and the digestibility rate increased with the raising milling degree.					
36358068	4	42	theme	quinoa	463:468	arg1	microstructure					445:458	the microstructure	441:458	the microstructure of quinoa with higher milling degree after cooking	441:509	Accordingly, the microstructure of quinoa with higher milling degree after cooking was more uniform and denser.					
36358068	4	42	theme	quinoa	463:468	arg1	uniform					520:526	uniform	520:526	uniform	520:526	Accordingly, the microstructure of quinoa with higher milling degree after cooking was more uniform and denser.					
36358068	8	43	theme	matrix	1075:1080	arg1	starch					1089:1094	protein matrix coated starch	1067:1094	protein matrix coated starch	1067:1094	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	2	44	theme	5.06	299:302	arg1	%					303:303	%	303:303	%	303:303	In particular, milling reduced the content of saponins from 5.06% to 0.23%.					
36358068	7	45	theme	kinetic	879:885	arg1	model					887:891	the digestion kinetic model	865:891	the digestion kinetic model	865:891	By fitting the starch digestograms and combining the digestion kinetic model, three digestion patterns of quinoa starch during milling were determined.					
36358068	8	46	theme	protein	1067:1073	arg1	starch					1089:1094	protein matrix coated starch	1067:1094	protein matrix coated starch	1067:1094	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36358068	6	47	theme	milling	800:806	arg1	degree					808:813	the raising milling degree	788:813	the raising milling degree	788:813	The digestibility of protein and starch was interrelated, and the digestibility rate increased with the raising milling degree.					
36358068	6	48	theme	protein	709:715	arg1	digestibility					692:704	The digestibility	688:704	The digestibility of protein and starch	688:726	The digestibility of protein and starch was interrelated, and the digestibility rate increased with the raising milling degree.					
36358068	5	49	theme	ordered	652:658	arg1	structure					660:668	the ordered structure	648:668	the ordered structure of quinoa starch	648:685	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	6	50	theme	raising	792:798	arg1	degree					808:813	the raising milling degree	788:813	the raising milling degree	788:813	The digestibility of protein and starch was interrelated, and the digestibility rate increased with the raising milling degree.					
36358068	2	51	theme	saponins	285:292	arg1	content					274:280	the content	270:280	the content of saponins	270:292	In particular, milling reduced the content of saponins from 5.06% to 0.23%.					
36358068	1	52	theme	starch	200:205	arg1	proportion					186:195	the proportion	182:195	the proportion of starch	182:205	With the gradual stripping of cellulose and protein in the milling process, the proportion of starch gradually increased to 91.35 %.					
36358068	0	53	theme	starch	61:66	arg1	digestion					48:56	in vitro digestion	39:56	in vitro digestion of starch during the milling process of quinoa	39:103	Effect of compositional interaction on in vitro digestion of starch during the milling process of quinoa.					
36358068	5	54	dep	infrared	558:565	arg1	FTIR					568:571	FTIR	568:571	FTIR	568:571	Fourier transform infrared (FTIR) analysis showed that starch-protein interaction was beneficial to protect the ordered structure of quinoa starch.					
36358068	8	55	theme	starch-protein	1100:1113	arg1	complex					1115:1121	starch-protein complex	1100:1121	starch-protein complex	1100:1121	The results of the confocal laser scanning microscope showed that the physical barrier composed of protein matrix coated starch and starch-protein complex affected starch digestion.					
36442429	2	0	theme	dynamic	651:657	arg1	testing					670:676	dynamic sinusoidal testing	651:676	dynamic sinusoidal testing	651:676	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	1	1	theme	osteoarthritis	299:312	arg1	stages					289:294	different stages	279:294	different stages of osteoarthritis	279:312	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	2	2	theme	material	712:719	arg1	modeling					721:728	fibril-reinforced poroelastic material modeling	682:728	fibril-reinforced poroelastic material modeling of stress-relaxation testing	682:757	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	5	3	theme	network	1343:1349	arg1	modulus					1351:1357	the greater strain-dependent fibril network modulus	1307:1357	the greater strain-dependent fibril network modulus	1307:1357	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	2	4	theme	fibril-reinforced	682:698	arg1	modeling					721:728	fibril-reinforced poroelastic material modeling	682:728	fibril-reinforced poroelastic material modeling of stress-relaxation testing	682:757	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	4	5	theme	superficial	1017:1027	arg1	cartilage					1029:1037	the superficial cartilage	1013:1037	the superficial cartilage (0-10 % of thickness)	1013:1059	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	2	6	theme	mechanical	603:612	arg1	properties					614:623	their viscoelastic and constituent-specific mechanical properties	559:623	properties	614:623	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	3	7	theme	collagen	844:851	arg1	organization					861:872	collagen network organization	844:872	collagen network organization (orientation angle and anisotropy)	844:907	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	3	7	theme	collagen	844:851	arg1	content					808:814	the proteoglycan content	791:814	the proteoglycan content using digital densitometry	791:841	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	0	8	theme	different	140:148	arg1	stages					150:155	different stages	140:155	different stages of osteoarthritis	140:173	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	8	9	theme	proteoglycan	1918:1929	arg1	loss					1931:1934	proteoglycan loss	1918:1934	proteoglycan loss	1918:1934	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	1	10	theme	knee	234:237	arg1	cartilage					247:255	human knee femoral cartilage	228:255	human knee femoral cartilage	228:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	4	11	theme	network	1243:1249	arg1	pretension					1216:1225	the pretension	1212:1225	the pretension of the collagen network	1212:1249	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	1	12	from	stages	289:294	arg1	well-known					265:274	well-known	265:274	well-known	265:274	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	1	12	from	stages	289:294	arg1	relationships					180:192	The relationships	176:192	The relationships between structure and function in human knee femoral cartilage	176:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	2	13	theme	normal	473:478	arg1	composition					369:379	depth-dependent composition	353:379	depth-dependent composition	353:379	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	13	theme	normal	473:478	arg1	structure					385:393	structure	385:393	structure	385:393	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	7	14	theme	proteoglycan	1778:1789	arg1	degradation					1791:1801	proteoglycan degradation	1778:1801	proteoglycan degradation	1778:1801	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	3	15	theme	orientation	875:885	arg1	angle					887:891	orientation angle	875:891	orientation angle	875:891	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	6	16	theme	cartilage	1460:1468	arg1	viscosity					1470:1478	greater cartilage viscosity	1452:1478	greater cartilage viscosity at a low loading frequency (0.005 Hz)	1452:1516	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	7	17	theme	network	1764:1770	arg1	pretension					1737:1746	the pretension	1733:1746	the pretension of the collagen network	1733:1770	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	3	18	theme	polarized	915:923	arg1	microscopy					931:940	polarized light microscopy	915:940	polarized light microscopy	915:940	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	1	19	from	function	216:223	arg1	cartilage					247:255	human knee femoral cartilage	228:255	human knee femoral cartilage	228:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	1	20	from	structure	202:210	arg1	cartilage					247:255	human knee femoral cartilage	228:255	human knee femoral cartilage	228:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	3	21	theme	collagen	946:953	arg1	content					955:961	collagen content	946:961	collagen content	946:961	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	0	22	theme	viscoelastic	79:90	arg1	properties					126:135	viscoelastic and constituent-specific material properties	79:135	viscoelastic and constituent-specific material properties	79:135	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	3	23	dep	organization	861:872	arg1	angle					887:891	orientation angle	875:891	orientation angle	875:891	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	3	23	dep	organization	861:872	arg1	anisotropy					897:906	anisotropy	897:906	anisotropy	897:906	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	8	24	theme	cartilage	1999:2007	arg1	viscosity					1978:1986	the viscosity	1974:1986	the viscosity of femoral cartilage	1974:2007	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	2	25	theme	stress-relaxation	733:749	arg1	testing					751:757	stress-relaxation testing	733:757	stress-relaxation testing	733:757	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	0	26	theme	constituent-specific	96:115	arg1	properties					126:135	viscoelastic and constituent-specific material properties	79:135	viscoelastic and constituent-specific material properties	79:135	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	3	27	dep	transform	977:985	arg1	infrared					987:994	infrared	987:994	transform infrared spectroscopy	977:1007	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	7	28	theme	network	1868:1874	arg1	behavior					1843:1850	the nonlinear mechanical behavior	1818:1850	the nonlinear mechanical behavior of the collagen network	1818:1874	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	7	29	theme	network	1702:1708	arg1	disorganization					1710:1724	collagen network disorganization	1693:1724	collagen network disorganization	1693:1724	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	4	30	theme	initial	1154:1160	arg1	modulus					1177:1183	the smaller initial fibril network modulus	1142:1183	the smaller initial fibril network modulus	1142:1183	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	2	31	theme	collagen	418:425	arg1	organization					435:446	collagen network organization	418:446	collagen network organization	418:446	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	6	32	theme	cartilage	1590:1598	arg1	viscosity					1600:1608	greater cartilage viscosity	1582:1608	greater cartilage viscosity at a high loading frequency (1 Hz)	1582:1643	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	8	33	theme	increased	2036:2044	arg1	viscosity					2046:2054	increased viscosity	2036:2054	increased viscosity	2036:2054	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	8	34	theme	loading	2087:2093	arg1	frequencies					2095:2105	completely different loading frequencies	2066:2105	completely different loading frequencies	2066:2105	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	6	35	theme	low	1485:1487	arg1	0.005 Hz					1508:1515	0.005 Hz	1508:1515	0.005 Hz	1508:1515	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	6	35	theme	low	1485:1487	arg1	frequency					1497:1505	a low loading frequency	1483:1505	a low loading frequency (0.005 Hz)	1483:1516	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	4	36	theme	network	1169:1175	arg1	modulus					1177:1183	the smaller initial fibril network modulus	1142:1183	the smaller initial fibril network modulus	1142:1183	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	0	37	theme	human	16:20	arg1	condyle					30:36	human femoral condyle	16:36	human femoral condyle	16:36	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	5	38	theme	strain-dependent	1319:1334	arg1	modulus					1351:1357	the greater strain-dependent fibril network modulus	1307:1357	the greater strain-dependent fibril network modulus	1307:1357	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	7	39	theme	nonlinear	1822:1830	arg1	behavior					1843:1850	the nonlinear mechanical behavior	1818:1850	the nonlinear mechanical behavior of the collagen network	1818:1874	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	2	40	theme	cartilage	521:529	arg1	composition					369:379	depth-dependent composition	353:379	depth-dependent composition	353:379	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	40	theme	cartilage	521:529	arg1	structure					385:393	structure	385:393	structure	385:393	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	41	theme	collagen	452:459	arg1	content					461:467	collagen content	452:467	collagen content	452:467	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	0	42	theme	condyle	30:36	arg1	Associations					0:11	Associations	0:11	Associations of human femoral condyle	0:36	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	6	43	from	frequency	1628:1636	arg1	viscosity					1600:1608	greater cartilage viscosity	1582:1608	greater cartilage viscosity at a high loading frequency (1 Hz)	1582:1643	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	2	44	theme	femoral	505:511	arg1	n = 47					532:537	n = 47	532:537	n = 47	532:537	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	44	theme	femoral	505:511	arg1	cartilage					521:529	osteoarthritic human femoral condyle cartilage	484:529	osteoarthritic human femoral condyle cartilage (n = 47)	484:538	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	6	45	theme	network	1538:1544	arg1	disorganization					1546:1560	the collagen network disorganization	1525:1560	the collagen network disorganization	1525:1560	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	8	46	theme	different	2077:2085	arg1	frequencies					2095:2105	completely different loading frequencies	2066:2105	completely different loading frequencies	2066:2105	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	2	47	theme	depth-dependent	353:367	arg1	composition					369:379	depth-dependent composition	353:379	depth-dependent composition	353:379	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	6	48	theme	greater	1582:1588	arg1	viscosity					1600:1608	greater cartilage viscosity	1582:1608	greater cartilage viscosity at a high loading frequency (1 Hz)	1582:1643	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	0	49	with	structure	48:56	arg1	properties					126:135	viscoelastic and constituent-specific material properties	79:135	viscoelastic and constituent-specific material properties	79:135	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	5	50	theme	nonlinear	1374:1382	arg1	behavior					1395:1402	nonlinear mechanical behavior	1374:1402	nonlinear mechanical behavior	1374:1402	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	6	51	theme	high	1615:1618	arg1	1 Hz					1639:1642	1 Hz	1639:1642	1 Hz	1639:1642	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	6	51	theme	high	1615:1618	arg1	frequency					1628:1636	a high loading frequency	1613:1636	a high loading frequency (1 Hz)	1613:1643	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	1	52	theme	different	279:287	arg1	stages					289:294	different stages	279:294	different stages of osteoarthritis	279:312	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	2	53	theme	sinusoidal	659:668	arg1	testing					670:676	dynamic sinusoidal testing	651:676	dynamic sinusoidal testing	651:676	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	6	54	theme	proteoglycan	1409:1420	arg1	loss					1422:1425	The proteoglycan loss	1405:1425	The proteoglycan loss	1405:1425	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	0	55	with	composition	62:72	arg1	properties					126:135	viscoelastic and constituent-specific material properties	79:135	viscoelastic and constituent-specific material properties	79:135	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	2	56	theme	poroelastic	700:710	arg1	modeling					721:728	fibril-reinforced poroelastic material modeling	682:728	fibril-reinforced poroelastic material modeling of stress-relaxation testing	682:757	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	3	57	theme	digital	822:828	arg1	densitometry					830:841	digital densitometry	822:841	digital densitometry	822:841	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	4	58	theme	collagen	1234:1241	arg1	network					1243:1249	the collagen network	1230:1249	the collagen network	1230:1249	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	6	59	theme	loading	1489:1495	arg1	0.005 Hz					1508:1515	0.005 Hz	1508:1515	0.005 Hz	1508:1515	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	6	59	theme	loading	1489:1495	arg1	frequency					1497:1505	a low loading frequency	1483:1505	a low loading frequency (0.005 Hz)	1483:1516	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	1	60	theme	human	228:232	arg1	cartilage					247:255	human knee femoral cartilage	228:255	human knee femoral cartilage	228:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	2	61	theme	constituent-specific	582:601	arg1	properties					614:623	their viscoelastic and constituent-specific mechanical properties	559:623	properties	614:623	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	3	62	theme	network	853:859	arg1	organization					861:872	collagen network organization	844:872	collagen network organization (orientation angle and anisotropy)	844:907	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	3	62	theme	network	853:859	arg1	content					808:814	the proteoglycan content	791:814	the proteoglycan content using digital densitometry	791:841	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	0	63	theme	osteoarthritis	160:173	arg1	stages					150:155	different stages	140:155	different stages of osteoarthritis	140:173	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	1	64	theme	femoral	239:245	arg1	cartilage					247:255	human knee femoral cartilage	228:255	human knee femoral cartilage	228:255	The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis.					
36442429	4	65	theme	thickness	1050:1058	arg1	thickness					1050:1058	thickness	1050:1058	thickness	1050:1058	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	4	65	theme	thickness	1050:1058	arg1	%					1045:1045	0-10 %	1040:1045	0-10 % of thickness	1040:1058	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	8	66	theme	femoral	1991:1997	arg1	cartilage					1999:2007	femoral cartilage	1991:2007	femoral cartilage	1991:2007	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	7	67	theme	collagen	1755:1762	arg1	network					1764:1770	the collagen network	1751:1770	the collagen network	1751:1770	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	4	68	dep	network	1075:1081	arg1	disorganization					1083:1097	disorganization	1083:1097	disorganization	1083:1097	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	4	68	dep	network	1075:1081	arg1	loss					1116:1119	proteoglycan loss	1103:1119	proteoglycan loss	1103:1119	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	6	69	theme	greater	1452:1458	arg1	viscosity					1470:1478	greater cartilage viscosity	1452:1478	greater cartilage viscosity at a low loading frequency (0.005 Hz)	1452:1516	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	8	70	theme	collagen	1940:1947	arg1	disorganization					1949:1963	collagen disorganization	1940:1963	collagen disorganization	1940:1963	Further, the results also highlight that proteoglycan loss and collagen disorganization increase the viscosity of femoral cartilage, but their contribution to increased viscosity occurs in completely different loading frequencies.					
36442429	3	71	theme	light	925:929	arg1	microscopy					931:940	polarized light microscopy	915:940	polarized light microscopy	915:940	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	6	72	theme	collagen	1529:1536	arg1	disorganization					1546:1560	the collagen network disorganization	1525:1560	the collagen network disorganization	1525:1560	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	5	73	theme	behavior	1395:1402	arg1	measure					1363:1369	a measure	1361:1369	a measure of nonlinear mechanical behavior	1361:1402	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	4	74	dep	cartilage	1029:1037	arg1	thickness					1050:1058	thickness	1050:1058	thickness	1050:1058	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	4	74	dep	cartilage	1029:1037	arg1	%					1045:1045	0-10 %	1040:1045	0-10 % of thickness	1040:1058	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	4	75	theme	proteoglycan	1103:1114	arg1	loss					1116:1119	proteoglycan loss	1103:1119	proteoglycan loss	1103:1119	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	2	76	theme	testing	751:757	arg1	modeling					721:728	fibril-reinforced poroelastic material modeling	682:728	fibril-reinforced poroelastic material modeling of stress-relaxation testing	682:757	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	76	theme	testing	751:757	arg1	testing					670:676	dynamic sinusoidal testing	651:676	dynamic sinusoidal testing	651:676	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	0	77	theme	material	117:124	arg1	properties					126:135	viscoelastic and constituent-specific material properties	79:135	viscoelastic and constituent-specific material properties	79:135	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	5	78	theme	proteoglycan	1269:1280	arg1	loss					1282:1285	the proteoglycan loss	1265:1285	the proteoglycan loss	1265:1285	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	3	79	dep	Fourier	969:975	arg1	transform					977:985	transform	977:985	transform infrared spectroscopy	977:1007	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	7	80	theme	collagen	1693:1700	arg1	disorganization					1710:1724	collagen network disorganization	1693:1724	collagen network disorganization	1693:1724	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	6	81	from	frequency	1497:1505	arg1	viscosity					1470:1478	greater cartilage viscosity	1452:1478	greater cartilage viscosity at a low loading frequency (0.005 Hz)	1452:1516	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	4	82	theme	collagen	1066:1073	arg1	network					1075:1081	the collagen network disorganization and proteoglycan loss	1062:1119	the collagen network disorganization and proteoglycan loss	1062:1119	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	2	83	theme	network	427:433	arg1	organization					435:446	collagen network organization	418:446	collagen network organization	418:446	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	7	84	theme	collagen	1859:1866	arg1	network					1868:1874	the collagen network	1855:1874	the collagen network	1855:1874	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	4	85	theme	smaller	1146:1152	arg1	modulus					1177:1183	the smaller initial fibril network modulus	1142:1183	the smaller initial fibril network modulus	1142:1183	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	0	86	theme	femoral	22:28	arg1	condyle					30:36	human femoral condyle	16:36	human femoral condyle	16:36	Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis.					
36442429	5	87	theme	greater	1311:1317	arg1	modulus					1351:1357	the greater strain-dependent fibril network modulus	1307:1357	the greater strain-dependent fibril network modulus	1307:1357	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	4	88	theme	fibril	1162:1167	arg1	modulus					1177:1183	the smaller initial fibril network modulus	1142:1183	the smaller initial fibril network modulus	1142:1183	In the superficial cartilage (0-10 % of thickness), the collagen network disorganization and proteoglycan loss were associated with the smaller initial fibril network modulus - a parameter representing the pretension of the collagen network.					
36442429	2	89	dep	composition	369:379	arg1	the					349:351	the	349:351	the	349:351	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	89	dep	composition	369:379	arg1	organization					435:446	collagen network organization	418:446	collagen network organization	418:446	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	89	dep	composition	369:379	arg1	content					461:467	collagen content	452:467	collagen content	452:467	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	89	dep	composition	369:379	arg1	content					409:415	proteoglycan content	396:415	proteoglycan content	396:415	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	5	90	theme	fibril	1336:1341	arg1	modulus					1351:1357	the greater strain-dependent fibril network modulus	1307:1357	the greater strain-dependent fibril network modulus	1307:1357	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36442429	7	91	theme	mechanical	1832:1841	arg1	behavior					1843:1850	the nonlinear mechanical behavior	1818:1850	the nonlinear mechanical behavior of the collagen network	1818:1874	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	2	92	theme	condyle	513:519	arg1	n = 47					532:537	n = 47	532:537	n = 47	532:537	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	92	theme	condyle	513:519	arg1	cartilage					521:529	osteoarthritic human femoral condyle cartilage	484:529	osteoarthritic human femoral condyle cartilage (n = 47)	484:538	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	7	93	theme	proteoglycan	1671:1682	arg1	loss					1684:1687	proteoglycan loss	1671:1687	proteoglycan loss	1671:1687	Our results suggest that proteoglycan loss and collagen network disorganization reduce the pretension of the collagen network while proteoglycan degradation also increases the nonlinear mechanical behavior of the collagen network.					
36442429	2	94	theme	human	499:503	arg1	n = 47					532:537	n = 47	532:537	n = 47	532:537	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	94	theme	human	499:503	arg1	cartilage					521:529	osteoarthritic human femoral condyle cartilage	484:529	osteoarthritic human femoral condyle cartilage (n = 47)	484:538	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	95	theme	proteoglycan	396:407	arg1	content					409:415	proteoglycan content	396:415	proteoglycan content	396:415	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	3	96	theme	proteoglycan	795:806	arg1	organization					861:872	collagen network organization	844:872	collagen network organization (orientation angle and anisotropy)	844:907	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	3	96	theme	proteoglycan	795:806	arg1	content					808:814	the proteoglycan content	791:814	the proteoglycan content using digital densitometry	791:841	We characterized the proteoglycan content using digital densitometry, collagen network organization (orientation angle and anisotropy) using polarized light microscopy and collagen content using Fourier transform infrared spectroscopy.					
36442429	2	97	theme	osteoarthritic	484:497	arg1	n = 47					532:537	n = 47	532:537	n = 47	532:537	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	2	97	theme	osteoarthritic	484:497	arg1	cartilage					521:529	osteoarthritic human femoral condyle cartilage	484:529	osteoarthritic human femoral condyle cartilage (n = 47)	484:538	Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelastic and constituent-specific mechanical properties that are obtained through dynamic sinusoidal testing and fibril-reinforced poroelastic material modeling of stress-relaxation testing, respectively.					
36442429	6	98	theme	loading	1620:1626	arg1	1 Hz					1639:1642	1 Hz	1639:1642	1 Hz	1639:1642	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	6	98	theme	loading	1620:1626	arg1	frequency					1628:1636	a high loading frequency	1613:1636	a high loading frequency (1 Hz)	1613:1643	The proteoglycan loss was also associated with greater cartilage viscosity at a low loading frequency (0.005 Hz), while the collagen network disorganization was associated with greater cartilage viscosity at a high loading frequency (1 Hz).					
36442429	5	99	theme	mechanical	1384:1393	arg1	behavior					1395:1402	nonlinear mechanical behavior	1374:1402	nonlinear mechanical behavior	1374:1402	Furthermore, the proteoglycan loss was associated with the greater strain-dependent fibril network modulus - a measure of nonlinear mechanical behavior.					
36499377	3	0	theme	freezing	517:524	arg1	temperatures					526:537	cold and freezing temperatures	508:537	cold and freezing temperatures	508:537	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	2	1	from	temperatures	335:346	arg1	environments					365:376	their natural environments	351:376	their natural environments	351:376	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	2	2	theme	resurrection	290:301	arg1	species					303:309	Only a few resurrection species	279:309	Only a few resurrection species	279:309	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	9	3	theme	freezing	1774:1781	arg1	tolerance					1783:1791	freezing tolerance	1774:1791	freezing tolerance (genes and genetic regulatory mechanisms)	1774:1833	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	7	4	theme	significant	1375:1385	arg1	changes					1418:1424	significant quantitative and compositional changes	1375:1424	significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1375:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	4	5	theme	leaf	693:696	arg1	content					704:710	leaf water content	693:710	leaf water content	693:710	Our data shows that leaf water content affects its thermodynamical properties during vitrification under low temperatures.					
36499377	1	6	theme	complete	180:187	arg1	dehydration					189:199	complete dehydration	180:199	complete dehydration of their leaves	180:215	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	6	7	theme	freezing	1032:1039	arg1	tolerance					1041:1049	the freezing tolerance	1028:1049	the freezing tolerance of H. rhodopensis	1028:1067	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	7	8	theme	early	1475:1479	arg1	proteins					1495:1502	early light-induced proteins	1475:1502	early light-induced proteins (ELIPs)	1475:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	8	theme	early	1475:1479	arg1	ELIPs					1505:1509	ELIPs	1505:1509	ELIPs	1505:1509	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	5	9	theme	proteins	895:902	arg1	synthesis					867:875	synthesis	867:875	synthesis of stress-induced proteins	867:902	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	9	theme	proteins	895:902	arg1	accumulation					839:850	accumulation	839:850	accumulation of sugars	839:860	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	9	theme	proteins	895:902	arg1	composition					826:836	membrane lipid composition	811:836	membrane lipid composition	811:836	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	9	10	theme	regulatory	1812:1821	arg1	mechanisms					1823:1832	genetic regulatory mechanisms	1804:1832	genetic regulatory mechanisms	1804:1832	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	3	11	theme	natural	624:630	arg1	conditions					661:670	natural and controlled environmental conditions	624:670	natural and controlled environmental conditions	624:670	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	5	12	theme	cold	981:984	arg1	temperatures					999:1010	both cold and freezing temperatures	976:1010	both cold and freezing temperatures	976:1010	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	7	13	theme	stress-induced	1429:1442	arg1	proteins					1444:1451	stress-induced proteins	1429:1451	stress-induced proteins	1429:1451	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	4	14	theme	low	778:780	arg1	temperatures					782:793	low temperatures	778:793	low temperatures	778:793	Our data shows that leaf water content affects its thermodynamical properties during vitrification under low temperatures.					
36499377	5	15	theme	freezing	990:997	arg1	temperatures					999:1010	both cold and freezing temperatures	976:1010	both cold and freezing temperatures	976:1010	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	7	16	from	proteins	1495:1502	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	6	17	theme	sucrose/hexoses	1081:1095	arg1	ratio					1097:1101	a sucrose/hexoses ratio	1079:1101	a sucrose/hexoses ratio in favor of hexoses during cold acclimation	1079:1145	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	8	18	theme	common	1552:1557	arg1	responses					1559:1567	common responses	1552:1567	common responses of H. rhodopensis plants to low temperature and desiccation	1552:1627	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	7	19	theme	changes	1418:1424	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	5	20	theme	membrane	811:818	arg1	composition					826:836	membrane lipid composition	811:836	membrane lipid composition	811:836	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	3	21	theme	controlled	636:645	arg1	conditions					661:670	natural and controlled environmental conditions	624:670	natural and controlled environmental conditions	624:670	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	5	22	theme	H.	958:959	arg1	adaptation					944:953	the adaptation	940:953	the adaptation of H. rhodopensis to both cold and freezing temperatures	940:1010	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	1	23	with	deal	170:173	arg1	dehydration					189:199	complete dehydration	180:199	complete dehydration of their leaves	180:215	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	6	24	theme	rhodopensis	1057:1067	arg1	tolerance					1041:1049	the freezing tolerance	1028:1049	the freezing tolerance of H. rhodopensis	1028:1067	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	6	25	from	ratio	1097:1101	arg1	favor					1106:1110	favor	1106:1110	favor	1106:1110	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	3	26	from	changes	572:578	arg1	the					583:585	the	583:585	the	583:585	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	7	27	from	changes	1418:1424	arg1	proteins					1495:1502	early light-induced proteins	1475:1502	early light-induced proteins (ELIPs)	1475:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	27	from	changes	1418:1424	arg1	proteins					1444:1451	stress-induced proteins	1429:1451	stress-induced proteins	1429:1451	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	27	from	changes	1418:1424	arg1	dehydrins					1461:1469	dehydrins	1461:1469	dehydrins	1461:1469	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	27	from	changes	1418:1424	arg1	ELIPs					1505:1509	ELIPs	1505:1509	ELIPs	1505:1509	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	9	28	theme	plants	1887:1892	arg1	resistance					1868:1877	the resistance	1864:1877	the resistance of crop plants	1864:1892	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	7	29	theme	compositional	1404:1416	arg1	changes					1418:1424	significant quantitative and compositional changes	1375:1424	significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1375:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	0	30	theme	Protective	0:9	arg1	Strategies					11:20	Protective Strategies	0:20	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.	0:136	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	7	31	theme	quantitative	1387:1398	arg1	changes					1418:1424	significant quantitative and compositional changes	1375:1424	significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1375:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	2	32	theme	freezing	452:459	arg1	tolerances					461:470	freezing tolerances	452:470	freezing tolerances	452:470	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	7	33	from	dehydrins	1461:1469	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	2	34	theme	key	423:425	arg1	adjustments					437:447	the key metabolic adjustments	419:447	the key metabolic adjustments of freezing tolerances	419:470	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	0	35	theme	rhodopensis	34:44	arg1	Strategies					11:20	Protective Strategies	0:20	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.	0:136	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	7	36	theme	fatty	1359:1363	arg1	acids					1365:1369	unsaturated/saturated fatty acids	1337:1369	unsaturated/saturated fatty acids	1337:1369	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	0	37	theme	Freezing	65:72	arg1	Tolerance					74:82	Freezing Tolerance	65:82	Freezing Tolerance	65:82	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	6	38	from	shift	1165:1169	arg1	favor					1174:1178	favor	1174:1178	favor	1174:1178	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	2	39	theme	natural	357:363	arg1	environments					365:376	their natural environments	351:376	their natural environments	351:376	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	5	40	theme	sugars	855:860	arg1	synthesis					867:875	synthesis	867:875	synthesis of stress-induced proteins	867:902	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	40	theme	sugars	855:860	arg1	accumulation					839:850	accumulation	839:850	accumulation of sugars	839:860	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	40	theme	sugars	855:860	arg1	composition					826:836	membrane lipid composition	811:836	membrane lipid composition	811:836	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	7	41	from	acids	1365:1369	arg1	proteins					1495:1502	early light-induced proteins	1475:1502	early light-induced proteins (ELIPs)	1475:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	41	from	acids	1365:1369	arg1	proteins					1444:1451	stress-induced proteins	1429:1451	stress-induced proteins	1429:1451	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	41	from	acids	1365:1369	arg1	dehydrins					1461:1469	dehydrins	1461:1469	dehydrins	1461:1469	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	41	from	acids	1365:1369	arg1	ELIPs					1505:1509	ELIPs	1505:1509	ELIPs	1505:1509	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	9	42	theme	Further	1719:1725	arg1	studies					1727:1733	Further studies	1719:1733	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms)	1719:1833	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	7	43	theme	elevated	1319:1326	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	1	44	dep	their	204:208	arg1	leaves					210:215	leaves	210:215	leaves	210:215	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	3	45	theme	temperatures	526:537	arg1	effect					498:503	the effect	494:503	the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis	494:616	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	1	46	theme	metabolic	241:249	arg1	activity					251:258	normal metabolic activity	234:258	normal metabolic activity	234:258	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	8	47	theme	protein	1699:1705	arg1	expression					1707:1716	dehydrins/ELIP protein expression	1684:1716	dehydrins/ELIP protein expression	1684:1716	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	9	48	theme	molecular	1742:1750	arg1	mechanisms					1752:1761	the molecular mechanisms	1738:1761	the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms)	1738:1833	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	3	49	theme	biochemical	560:570	arg1	changes					572:578	physiological and biochemical changes	542:578	physiological and biochemical changes in the leaves of Haberlea rhodopensis	542:616	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	8	50	dep	H.	1572:1573	arg1	rhodopensis					1575:1585	H. rhodopensis	1572:1585	H. rhodopensis plants	1572:1592	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	3	51	theme	physiological	542:554	arg1	changes					572:578	physiological and biochemical changes	542:578	physiological and biochemical changes in the leaves of Haberlea rhodopensis	542:616	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	9	52	dep	tolerance	1783:1791	arg1	mechanisms					1823:1832	genetic regulatory mechanisms	1804:1832	genetic regulatory mechanisms	1804:1832	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	9	52	dep	tolerance	1783:1791	arg1	genes					1794:1798	genes	1794:1798	genes	1794:1798	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	6	53	theme	freezing	1208:1215	arg1	temperatures					1217:1228	freezing temperatures	1208:1228	freezing temperatures	1208:1228	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	3	54	from	effect	498:503	arg1	changes					572:578	physiological and biochemical changes	542:578	physiological and biochemical changes in the leaves of Haberlea rhodopensis	542:616	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	2	55	theme	freezing	326:333	arg1	temperatures					335:346	freezing temperatures	326:346	freezing temperatures in their natural environments	326:376	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	7	56	from	ratio	1328:1332	arg1	proteins					1495:1502	early light-induced proteins	1475:1502	early light-induced proteins (ELIPs)	1475:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	56	from	ratio	1328:1332	arg1	proteins					1444:1451	stress-induced proteins	1429:1451	stress-induced proteins	1429:1451	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	56	from	ratio	1328:1332	arg1	dehydrins					1461:1469	dehydrins	1461:1469	dehydrins	1461:1469	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	56	from	ratio	1328:1332	arg1	ELIPs					1505:1509	ELIPs	1505:1509	ELIPs	1505:1509	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	4	57	theme	water	698:702	arg1	content					704:710	leaf water content	693:710	leaf water content	693:710	Our data shows that leaf water content affects its thermodynamical properties during vitrification under low temperatures.					
36499377	1	58	theme	their	204:208	arg1	dehydration					189:199	complete dehydration	180:199	complete dehydration of their leaves	180:215	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	9	59	theme	genetic	1804:1810	arg1	mechanisms					1823:1832	genetic regulatory mechanisms	1804:1832	genetic regulatory mechanisms	1804:1832	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	7	60	theme	light-induced	1481:1493	arg1	proteins					1495:1502	early light-induced proteins	1475:1502	early light-induced proteins (ELIPs)	1475:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	7	60	theme	light-induced	1481:1493	arg1	ELIPs					1505:1509	ELIPs	1505:1509	ELIPs	1505:1509	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	5	61	from	changes	800:806	arg1	synthesis					867:875	synthesis	867:875	synthesis of stress-induced proteins	867:902	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	61	from	changes	800:806	arg1	accumulation					839:850	accumulation	839:850	accumulation of sugars	839:860	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	5	61	from	changes	800:806	arg1	composition					826:836	membrane lipid composition	811:836	membrane lipid composition	811:836	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	3	62	theme	Haberlea	597:604	arg1	rhodopensis					606:616	Haberlea rhodopensis	597:616	Haberlea rhodopensis	597:616	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	3	63	theme	environmental	647:659	arg1	conditions					661:670	natural and controlled environmental conditions	624:670	natural and controlled environmental conditions	624:670	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	1	64	theme	Resurrection	138:149	arg1	plants					151:156	Resurrection plants	138:156	Resurrection plants	138:156	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	6	65	theme	leaf	1255:1258	arg1	desiccation					1260:1270	leaf desiccation	1255:1270	leaf desiccation	1255:1270	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	0	66	theme	Tolerance	74:82	arg1	Acquisition					50:60	Acquisition	50:60	Acquisition of Freezing Tolerance	50:82	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	5	67	theme	stress-induced	880:893	arg1	proteins					895:902	stress-induced proteins	880:902	stress-induced proteins	880:902	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	8	68	theme	H.	1572:1573	arg1	plants					1587:1592	H. rhodopensis plants	1572:1592	H. rhodopensis plants	1572:1592	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	5	69	theme	lipid	820:824	arg1	composition					826:836	membrane lipid composition	811:836	membrane lipid composition	811:836	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	8	70	theme	plants	1587:1592	arg1	responses					1559:1567	common responses	1552:1567	common responses of H. rhodopensis plants to low temperature and desiccation	1552:1627	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	4	71	theme	thermodynamical	724:738	arg1	properties					740:749	its thermodynamical properties	720:749	its thermodynamical properties	720:749	Our data shows that leaf water content affects its thermodynamical properties during vitrification under low temperatures.					
36499377	3	72	dep	the	583:585	arg1	leaves					587:592	leaves	587:592	leaves	587:592	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	6	73	theme	H.	1054:1055	arg1	rhodopensis					1057:1067	H. rhodopensis	1054:1067	H. rhodopensis	1054:1067	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	9	74	theme	crop	1882:1885	arg1	plants					1887:1892	crop plants	1882:1892	crop plants	1882:1892	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	8	75	theme	low	1597:1599	arg1	temperature					1601:1611	low temperature	1597:1611	low temperature	1597:1611	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	0	76	theme	Low	121:123	arg1	Temperature					125:135	Low Temperature	121:135	Low Temperature	121:135	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	9	77	from	studies	1727:1733	arg1	mechanisms					1752:1761	the molecular mechanisms	1738:1761	the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms)	1738:1833	Further studies on the molecular mechanisms underlying freezing tolerance (genes and genetic regulatory mechanisms) may help breeders to improve the resistance of crop plants.					
36499377	7	78	from	proteins	1444:1451	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	6	79	theme	cold	1130:1133	arg1	acclimation					1135:1145	cold acclimation	1130:1145	cold acclimation	1130:1145	In particular, the freezing tolerance of H. rhodopensis relies on a sucrose/hexoses ratio in favor of hexoses during cold acclimation, while there is a shift in favor of sucrose upon exposure to freezing temperatures, especially evident when leaf desiccation is relevant.					
36499377	2	80	theme	tolerances	461:470	arg1	adjustments					437:447	the key metabolic adjustments	419:447	the key metabolic adjustments of freezing tolerances	419:470	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	2	81	theme	interesting	391:401	arg1	models					403:408	interesting models	391:408	interesting models	391:408	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	0	82	theme	Haberlea	25:32	arg1	rhodopensis					34:44	Haberlea rhodopensis	25:44	Haberlea rhodopensis	25:44	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	7	83	theme	acids	1365:1369	arg1	ratio					1328:1332	an elevated ratio	1316:1332	an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs)	1316:1510	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	5	84	dep	H.	958:959	arg1	rhodopensis					961:971	H. rhodopensis	958:971	H. rhodopensis	958:971	The changes in membrane lipid composition, accumulation of sugars, and synthesis of stress-induced proteins were significantly activated during the adaptation of H. rhodopensis to both cold and freezing temperatures.					
36499377	2	85	theme	metabolic	427:435	arg1	adjustments					437:447	the key metabolic adjustments	419:447	the key metabolic adjustments of freezing tolerances	419:470	Only a few resurrection species are exposed to freezing temperatures in their natural environments, making them interesting models to study the key metabolic adjustments of freezing tolerances.					
36499377	7	86	theme	unsaturated/saturated	1337:1357	arg1	acids					1365:1369	unsaturated/saturated fatty acids	1337:1369	unsaturated/saturated fatty acids	1337:1369	This pattern was paralleled by an elevated ratio of unsaturated/saturated fatty acids and significant quantitative and compositional changes in stress-induced proteins, namely dehydrins and early light-induced proteins (ELIPs).					
36499377	8	87	theme	sugars	1657:1662	arg1	accumulation					1641:1652	the accumulation	1637:1652	the accumulation of sugars	1637:1662	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	8	87	theme	sugars	1657:1662	arg1	upregulation					1668:1679	upregulation	1668:1679	upregulation of dehydrins/ELIP protein expression	1668:1716	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	3	88	theme	cold	508:511	arg1	temperatures					526:537	cold and freezing temperatures	508:537	cold and freezing temperatures	508:537	Here, we investigate the effect of cold and freezing temperatures on physiological and biochemical changes in the leaves of Haberlea rhodopensis under natural and controlled environmental conditions.					
36499377	8	89	theme	dehydrins/ELIP	1684:1697	arg1	expression					1707:1716	dehydrins/ELIP protein expression	1684:1716	dehydrins/ELIP protein expression	1684:1716	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	1	90	theme	normal	234:239	arg1	activity					251:258	normal metabolic activity	234:258	normal metabolic activity	234:258	Resurrection plants are able to deal with complete dehydration of their leaves and then recover normal metabolic activity after rehydration.					
36499377	0	91	dep	Strategies	11:20	arg1	Interaction					85:95	Interaction	85:95	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.	0:136	Protective Strategies of Haberlea rhodopensis for Acquisition of Freezing Tolerance: Interaction between Dehydration and Low Temperature.					
36499377	8	92	theme	expression	1707:1716	arg1	accumulation					1641:1652	the accumulation	1637:1652	the accumulation of sugars	1637:1662	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36499377	8	92	theme	expression	1707:1716	arg1	upregulation					1668:1679	upregulation	1668:1679	upregulation of dehydrins/ELIP protein expression	1668:1716	Taken together, our data indicate that common responses of H. rhodopensis plants to low temperature and desiccation involve the accumulation of sugars and upregulation of dehydrins/ELIP protein expression.					
36576144	5	0	theme	In	861:862	arg1	cytotoxicity					870:881	In vitro cytotoxicity	861:881	In vitro cytotoxicity of Cur-AuNPs	861:894	In vitro cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines.					
36576144	5	1	theme	MDA-MB	927:932	arg1	lines					943:947	MDA-MB 231 cell lines	927:947	MDA-MB 231 cell lines	927:947	In vitro cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines.					
36576144	2	2	theme	Cu-Au	408:412	arg1	NPs					414:416	prepared Cu-Au NPs	399:416	prepared Cu-Au NPs	399:416	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	6	3	dep	Cur-AuNPs	991:999	arg1	contain					1006:1012	contain	1006:1012	contain biomimetic nanocomposites	1006:1038	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	6	4	theme	Cur-AuNPs	991:999	arg1	activity					979:986	activity	979:986	activity	979:986	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	6	4	theme	Cur-AuNPs	991:999	arg1	use					954:956	The use	950:956	The use of above studies	950:973	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	2	5	theme	prepared	399:406	arg1	NPs					414:416	prepared Cu-Au NPs	399:416	prepared Cu-Au NPs	399:416	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	3	6	theme	biomineralization	606:622	arg1	property					624:631	biomineralization property	606:631	biomineralization property	606:631	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	7	theme	scaffolds	194:202	arg1	preparation					153:163	the preparation	149:163	the preparation of biomimetic nanocomposites scaffolds	149:202	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	5	8	theme	cell	938:941	arg1	lines					943:947	MDA-MB 231 cell lines	927:947	MDA-MB 231 cell lines	927:947	In vitro cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines.					
36576144	3	9	theme	simulated	581:589	arg1	fluid					596:600	simulated body fluid	581:600	simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption	581:722	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	2	10	theme	characterization	476:491	arg1	techniques					493:502	various characterization techniques	468:502	various characterization techniques	468:502	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	4	11	theme	NPs	758:760	arg1	activity					739:746	Antibacterial activity	725:746	Antibacterial activity of Cur-Au NPs and their nanocomposites	725:785	Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against Escherichia coli (E. coli) and Staphylococcus aureus.					
36576144	6	12	theme	studies	967:973	arg1	activity					979:986	activity	979:986	activity	979:986	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	6	12	theme	studies	967:973	arg1	use					954:956	The use	950:956	The use of above studies	950:973	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	1	13	with	materials	313:321	arg1	composite					353:361	chitosan-sodium alginate composite	328:361	chitosan-sodium alginate composite	328:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	14	theme	solvent	110:116	arg1	technique					126:134	A solvent casting technique	108:134	A solvent casting technique	108:134	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	15	theme	various	213:219	arg1	concentrations					221:234	three various concentrations	207:234	three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	207:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	6	16	theme	above	961:965	arg1	studies					967:973	above studies	961:973	above studies	961:973	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	1	17	theme	casting	118:124	arg1	technique					126:134	A solvent casting technique	108:134	A solvent casting technique	108:134	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	2	18	theme	nanocomposites	433:446	arg1	properties					385:394	The physico-chemical properties	364:394	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites	364:446	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	2	19	theme	biomimetic	422:431	arg1	nanocomposites					433:446	biomimetic nanocomposites	422:446	biomimetic nanocomposites	422:446	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	0	20	theme	nanoparticles-chitosan/sodium	21:49	arg1	nanocomposite					60:72	gold nanoparticles-chitosan/sodium alginate nanocomposite	16:72	gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications	16:105	Curcumin loaded gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications.					
36576144	1	21	theme	filler	306:311	arg1	materials					313:321	filler materials	306:321	filler materials with chitosan-sodium alginate composite	306:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	5	22	dep	In	861:862	arg1	vitro					864:868	vitro	864:868	vitro	864:868	In vitro cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines.					
36576144	3	23	theme	phosphate	652:660	arg1	PBS					677:679	PBS	677:679	PBS	677:679	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	3	23	theme	phosphate	652:660	arg1	saline					669:674	phosphate buffer saline	652:674	phosphate buffer saline (PBS)	652:680	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	24	theme	Curcumin	239:246	arg1	2 ml					297:300	2 ml	297:300	2 ml	297:300	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	24	theme	Curcumin	239:246	arg1	Cur-AuNPs-1					275:285	Cur-AuNPs-1	275:285	Cur-AuNPs-1	275:285	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	24	theme	Curcumin	239:246	arg1	nanoparticles					260:272	Curcumin loaded gold nanoparticles	239:272	Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	239:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	0	25	theme	gold	16:19	arg1	nanocomposite					60:72	gold nanoparticles-chitosan/sodium alginate nanocomposite	16:72	gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications	16:105	Curcumin loaded gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications.					
36576144	3	26	theme	buffer	662:667	arg1	PBS					677:679	PBS	677:679	PBS	677:679	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	3	26	theme	buffer	662:667	arg1	saline					669:674	phosphate buffer saline	652:674	phosphate buffer saline (PBS)	652:680	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	27	theme	loaded	248:253	arg1	2 ml					297:300	2 ml	297:300	2 ml	297:300	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	27	theme	loaded	248:253	arg1	Cur-AuNPs-1					275:285	Cur-AuNPs-1	275:285	Cur-AuNPs-1	275:285	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	27	theme	loaded	248:253	arg1	nanoparticles					260:272	Curcumin loaded gold nanoparticles	239:272	Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	239:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	2	28	theme	various	468:474	arg1	techniques					493:502	various characterization techniques	468:502	various characterization techniques	468:502	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	3	29	theme	In	505:506	arg1	biocompatibility					514:529	In vitro biocompatibility	505:529	In vitro biocompatibility of biomimetic nanocomposites	505:558	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	30	theme	gold	255:258	arg1	2 ml					297:300	2 ml	297:300	2 ml	297:300	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	30	theme	gold	255:258	arg1	Cur-AuNPs-1					275:285	Cur-AuNPs-1	275:285	Cur-AuNPs-1	275:285	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	30	theme	gold	255:258	arg1	nanoparticles					260:272	Curcumin loaded gold nanoparticles	239:272	Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	239:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	0	31	theme	alginate	51:58	arg1	nanocomposite					60:72	gold nanoparticles-chitosan/sodium alginate nanocomposite	16:72	gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications	16:105	Curcumin loaded gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications.					
36576144	1	32	theme	chitosan-sodium	328:342	arg1	composite					353:361	chitosan-sodium alginate composite	328:361	chitosan-sodium alginate composite	328:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	3	33	dep	In	505:506	arg1	vitro					508:512	vitro	508:512	vitro	508:512	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	34	theme	nanoparticles	260:272	arg1	concentrations					221:234	three various concentrations	207:234	three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	207:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	0	35	theme	nanotheranostic	78:92	arg1	applications					94:105	nanotheranostic applications	78:105	nanotheranostic applications	78:105	Curcumin loaded gold nanoparticles-chitosan/sodium alginate nanocomposite for nanotheranostic applications.					
36576144	1	36	theme	alginate	344:351	arg1	composite					353:361	chitosan-sodium alginate composite	328:361	chitosan-sodium alginate composite	328:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	37	used	used	140:143	arg2	technique					126:134	A solvent casting technique	108:134	A solvent casting technique	108:134	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	3	38	theme	body	591:594	arg1	fluid					596:600	simulated body fluid	581:600	simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption	581:722	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	6	39	theme	biomimetic	1014:1023	arg1	nanocomposites					1025:1038	biomimetic nanocomposites	1014:1038	biomimetic nanocomposites	1014:1038	The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.					
36576144	3	40	theme	protein	705:711	arg1	property					695:702	property	695:702	property	695:702	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	3	40	theme	protein	705:711	arg1	adsorption					713:722	protein adsorption	705:722	protein adsorption	705:722	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	4	41	theme	nanocomposites	772:785	arg1	activity					739:746	Antibacterial activity	725:746	Antibacterial activity of Cur-Au NPs and their nanocomposites	725:785	Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against Escherichia coli (E. coli) and Staphylococcus aureus.					
36576144	2	42	theme	physico-chemical	368:383	arg1	properties					385:394	The physico-chemical properties	364:394	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites	364:446	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	4	43	dep	coli	819:822	arg1	coli					828:831	E. coli	825:831	E. coli	825:831	Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against Escherichia coli (E. coli) and Staphylococcus aureus.					
36576144	3	44	theme	HAp	634:636	arg1	formation					638:646	HAp formation	634:646	HAp formation	634:646	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	45	dep	nanoparticles	260:272	arg1	1.5					288:290	1.5	288:290	1.5	288:290	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	45	dep	nanoparticles	260:272	arg1	2 ml					297:300	2 ml	297:300	2 ml	297:300	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	45	dep	nanoparticles	260:272	arg1	Cur-AuNPs-1					275:285	Cur-AuNPs-1	275:285	Cur-AuNPs-1	275:285	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	1	45	dep	nanoparticles	260:272	arg1	nanoparticles					260:272	Curcumin loaded gold nanoparticles	239:272	Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite	239:361	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	2	46	theme	NPs	414:416	arg1	properties					385:394	The physico-chemical properties	364:394	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites	364:446	The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques.					
36576144	3	47	theme	biomimetic	534:543	arg1	nanocomposites					545:558	biomimetic nanocomposites	534:558	biomimetic nanocomposites	534:558	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	3	48	theme	nanocomposites	545:558	arg1	biocompatibility					514:529	In vitro biocompatibility	505:529	In vitro biocompatibility of biomimetic nanocomposites	505:558	In vitro biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption.					
36576144	1	49	theme	biomimetic	168:177	arg1	scaffolds					194:202	biomimetic nanocomposites scaffolds	168:202	biomimetic nanocomposites scaffolds	168:202	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
36576144	4	50	theme	Cur-Au	751:756	arg1	NPs					758:760	Cur-Au NPs	751:760	Cur-Au NPs	751:760	Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against Escherichia coli (E. coli) and Staphylococcus aureus.					
36576144	5	51	theme	Cur-AuNPs	886:894	arg1	cytotoxicity					870:881	In vitro cytotoxicity	861:881	In vitro cytotoxicity of Cur-AuNPs	861:894	In vitro cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines.					
36576144	4	52	theme	Antibacterial	725:737	arg1	activity					739:746	Antibacterial activity	725:746	Antibacterial activity of Cur-Au NPs and their nanocomposites	725:785	Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against Escherichia coli (E. coli) and Staphylococcus aureus.					
36576144	1	53	theme	nanocomposites	179:192	arg1	scaffolds					194:202	biomimetic nanocomposites scaffolds	168:202	biomimetic nanocomposites scaffolds	168:202	A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite.					
37085062	5	0	theme	-copolymerized	710:723	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	7	1	theme	NIH3T3	1090:1095	arg1	lines					1112:1116	NIH3T3 and CT-2A cell lines	1090:1116	lines	1112:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	6	2	theme	/ALG-EDA/AgNP	948:960	arg1	system					972:977	the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system	927:977	the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system	927:977	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	6	2	theme	/ALG-EDA/AgNP	948:960	arg1	effective					982:990	effective	982:990	effective	982:990	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	5	3	theme	HEMIN	725:729	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	0	4	theme	accelerated	96:106	arg1	healing					123:129	accelerated diabetic wound healing	96:129	accelerated diabetic wound healing	96:129	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	4	5	theme	antibacterial	555:567	arg1	activities					585:594	the antibacterial and antioxidant activities	551:594	the antibacterial and antioxidant activities in mice with diabetes-induced wounds	551:631	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	9	6	from	conclusion	1295:1304	arg1	promising					1350:1358	promising	1350:1358	promising	1350:1358	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	9	6	from	conclusion	1295:1304	arg1	biocomposite					1311:1322	the biocomposite	1307:1322	the biocomposite reported herein	1307:1338	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	4	7	theme	thermosensitive	511:525	arg1	properties					527:536	thermosensitive properties	511:536	thermosensitive properties	511:536	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	1	8	with	patients	154:161	arg1	diabetes					168:175	diabetes	168:175	diabetes	168:175	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	5	9	theme	poly	675:678	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	2	10	theme	oxidative	286:294	arg1	stress					296:301	oxidative stress	286:301	oxidative stress	286:301	These wounds are exacerbated by oxidative stress and microbial infections resulting from hyperglycemia.					
37085062	0	11	theme	wound	117:121	arg1	healing					123:129	accelerated diabetic wound healing	96:129	accelerated diabetic wound healing	96:129	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	5	12	theme	acrylamide	692:701	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	5	13	theme	N-isopropyl	680:690	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	4	14	with	hydrogel	497:504	arg1	properties					527:536	thermosensitive properties	511:536	thermosensitive properties	511:536	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	0	15	theme	diabetic	108:115	arg1	healing					123:129	accelerated diabetic wound healing	96:129	accelerated diabetic wound healing	96:129	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	9	16	theme	diabetic	1374:1381	arg1	wounds					1388:1393	diabetic skin wounds	1374:1393	diabetic skin wounds	1374:1393	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	5	17	theme	antibacterial	865:877	arg1	agent					879:883	an antibacterial agent	862:883	an antibacterial agent	862:883	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	5	18	theme	Ag	805:806	arg1	AgNPs					823:827	AgNPs	823:827	AgNPs	823:827	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	5	18	theme	Ag	805:806	arg1	nanoparticles					808:820	Ag nanoparticles	805:820	Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent	805:883	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	0	19	theme	thermosensitive	16:30	arg1	hydrogel					32:39	Multifunctional thermosensitive hydrogel	0:39	Multifunctional thermosensitive hydrogel	0:39	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	9	20	theme	skin	1383:1386	arg1	wounds					1388:1393	diabetic skin wounds	1374:1393	diabetic skin wounds	1374:1393	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	5	21	theme	NIPAM	704:708	arg1	NIPAM-co-HEMIN					732:745	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	NIPAM-co-HEMIN	732:745	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	1	22	from	wounds	144:149	arg1	patients					154:161	patients	154:161	patients with diabetes	154:175	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	4	23	with	mice	599:602	arg1	wounds					626:631	diabetes-induced wounds	609:631	diabetes-induced wounds	609:631	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	1	24	theme	concerning	183:192	arg1	issue					194:198	a concerning issue	181:198	a concerning issue associated with amputation and a high mortality rate	181:251	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	1	24	theme	concerning	183:192	arg1	wounds					144:149	Non-healing wounds	132:149	Non-healing wounds in patients with diabetes	132:175	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	0	25	theme	Multifunctional	0:14	arg1	hydrogel					32:39	Multifunctional thermosensitive hydrogel	0:39	Multifunctional thermosensitive hydrogel	0:39	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	4	26	theme	diabetes-induced	609:624	arg1	wounds					626:631	diabetes-induced wounds	609:631	diabetes-induced wounds	609:631	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	8	27	theme	healing	1242:1248	arg1	process					1250:1256	the healing process	1238:1256	the healing process	1238:1256	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
37085062	2	28	theme	microbial	307:315	arg1	infections					317:326	microbial infections	307:326	microbial infections resulting from hyperglycemia	307:355	These wounds are exacerbated by oxidative stress and microbial infections resulting from hyperglycemia.					
37085062	3	29	theme	wound	402:406	arg1	beds					408:411	wound beds	402:411	wound beds	402:411	Therefore, advanced materials for repairing wound beds must be identified urgently.					
37085062	5	30	theme	ALG-EDA	777:783	arg1	biomaterials					786:797	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	biomaterials	786:797	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	4	31	theme	applicable	476:485	arg1	hydrogel					497:504	a topically applicable composite hydrogel	464:504	a topically applicable composite hydrogel with thermosensitive properties	464:536	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	0	32	theme	alginate	50:57	arg1	composites					81:90	alginate and P(NIPAM-co-HEMIN) composites	50:90	alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing	50:129	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	7	33	theme	cell	1107:1110	arg1	lines					1112:1116	NIH3T3 and CT-2A cell lines	1090:1116	lines	1112:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	9	34	from	promising	1350:1358	arg1	conclusion					1295:1304	conclusion	1295:1304	conclusion	1295:1304	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	8	35	theme	diabetic	1133:1140	arg1	mice					1142:1145	diabetic mice	1133:1145	diabetic mice treated with the composite system	1133:1179	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
37085062	7	36	theme	cellular	1069:1076	arg1	toxicity					1078:1085	low cellular toxicity	1065:1085	low cellular toxicity in NIH3T3 and CT-2A cell lines	1065:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	3	37	theme	advanced	369:376	arg1	materials					378:386	advanced materials	369:386	advanced materials for repairing wound beds	369:411	Therefore, advanced materials for repairing wound beds must be identified urgently.					
37085062	0	38	theme	P	63:63	arg1	composites					81:90	alginate and P(NIPAM-co-HEMIN) composites	50:90	alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing	50:129	Multifunctional thermosensitive hydrogel based on alginate and P(NIPAM-co-HEMIN) composites for accelerated diabetic wound healing.					
37085062	4	39	theme	antioxidant	573:583	arg1	activities					585:594	the antibacterial and antioxidant activities	551:594	the antibacterial and antioxidant activities in mice with diabetes-induced wounds	551:631	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	4	40	theme	composite	487:495	arg1	hydrogel					497:504	a topically applicable composite hydrogel	464:504	a topically applicable composite hydrogel with thermosensitive properties	464:536	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	8	41	theme	composite	1164:1172	arg1	system					1174:1179	the composite system	1160:1179	the composite system	1160:1179	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
37085062	6	42	theme	composite	962:970	arg1	system					972:977	the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system	927:977	the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system	927:977	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	6	42	theme	composite	962:970	arg1	effective					982:990	effective	982:990	effective	982:990	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	9	43	theme	bacterial	1429:1437	arg1	microbes					1439:1446	bacterial microbes	1429:1446	bacterial microbes	1429:1446	In conclusion, the biocomposite reported herein is highly promising for repairing diabetic skin wounds and treating infections caused by bacterial microbes.					
37085062	7	44	theme	CT-2A	1101:1105	arg1	lines					1112:1116	NIH3T3 and CT-2A cell lines	1090:1116	lines	1112:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	6	45	theme	tests	911:915	arg1	Results					886:892	Results	886:892	Results of antibacterial tests	886:915	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	5	46	theme	amine-modified	752:765	arg1	biomaterials					786:797	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	biomaterials	786:797	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	6	47	theme	antibacterial	897:909	arg1	tests					911:915	antibacterial tests	897:915	antibacterial tests	897:915	Results of antibacterial tests show that the p(NIPAM-co-HEMIN)/ALG-EDA/AgNP composite system is effective against E. coli and S. aureus.					
37085062	7	48	theme	low	1065:1067	arg1	toxicity					1078:1085	low cellular toxicity	1065:1085	low cellular toxicity in NIH3T3 and CT-2A cell lines	1065:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	1	49	theme	Non-healing	132:142	arg1	wounds					144:149	Non-healing wounds	132:149	Non-healing wounds in patients with diabetes	132:175	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	1	49	theme	Non-healing	132:142	arg1	issue					194:198	a concerning issue	181:198	a concerning issue associated with amputation and a high mortality rate	181:251	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	5	50	theme	alginate	767:774	arg1	biomaterials					786:797	poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials	675:797	biomaterials	786:797	This composite is developed by combining poly N-isopropyl acrylamide (NIPAM)-copolymerized HEMIN (NIPAM-co-HEMIN) and amine-modified alginate (ALG-EDA) biomaterials, with Ag nanoparticles (AgNPs) incorporated into the system as an antibacterial agent.					
37085062	7	51	theme	AgNP	1041:1044	arg1	composite					1046:1054	the AgNP composite	1037:1054	the AgNP composite	1037:1054	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	8	52	theme	collagen	1272:1279	arg1	synthesis					1281:1289	collagen synthesis	1272:1289	collagen synthesis	1272:1289	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
37085062	1	53	theme	high	233:236	arg1	rate					248:251	a high mortality rate	231:251	a high mortality rate	231:251	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	7	54	from	toxicity	1078:1085	arg1	lines					1112:1116	NIH3T3 and CT-2A cell lines	1090:1116	lines	1112:1116	Additionally, the AgNP composite exhibits low cellular toxicity in NIH3T3 and CT-2A cell lines.					
37085062	8	55	theme	composite	1209:1217	arg1	system					1219:1224	the composite system	1205:1224	the composite system	1205:1224	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
37085062	1	56	theme	mortality	238:246	arg1	rate					248:251	a high mortality rate	231:251	a high mortality rate	231:251	Non-healing wounds in patients with diabetes are a concerning issue associated with amputation and a high mortality rate.					
37085062	4	57	from	activities	585:594	arg1	mice					599:602	mice	599:602	mice with diabetes-induced wounds	599:631	This paper introduces a topically applicable composite hydrogel with thermosensitive properties and presents the antibacterial and antioxidant activities in mice with diabetes-induced wounds.					
37085062	8	58	from	wounds	1123:1128	arg1	mice					1142:1145	diabetic mice	1133:1145	diabetic mice treated with the composite system	1133:1179	The wounds in diabetic mice treated with the composite system healed in <12 days, and the composite system accelerated the healing process by increasing collagen synthesis.					
35550171	0	0	from	effect	18:23	arg1	foams					70:74	chitosan/alginate-based foams	46:74	chitosan/alginate-based foams	46:74	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	0	0	from	effect	18:23	arg1	release					83:89	release	83:89	release	83:89	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	0	0	from	effect	18:23	arg1	activity					106:113	antifungal activity	95:113	antifungal activity	95:113	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	2	1	theme	composition	313:323	arg1	effect					275:280	the effect	271:280	the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities	271:431	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	2	from	effect	275:280	arg1	activities					422:431	antifungal activities	411:431	antifungal activities	411:431	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	2	from	effect	275:280	arg1	release					399:405	the clotrimazole release	382:405	the clotrimazole release	382:405	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	5	3	theme	clotrimazole	865:876	arg1	degree					855:860	the ionization degree	840:860	the ionization degree of clotrimazole	840:876	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	5	3	theme	clotrimazole	865:876	arg1	excipients					892:901	the other excipients	882:901	the other excipients	882:901	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	2	4	from	oxide	294:298	arg1	foams					373:377	chitosan/alginate-based buccal foams	342:377	chitosan/alginate-based buccal foams	342:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	0	5	theme	antifungal	95:104	arg1	activity					106:113	antifungal activity	95:113	antifungal activity	95:113	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	7	6	theme	due	1077:1079	arg1	foams					1071:1075	drug-free foams	1061:1075	drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate	1061:1211	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	3	7	theme	drug	496:499	arg1	interactions					476:487	the interactions	472:487	the interactions of the drug with excipients in the foams	472:528	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	4	8	theme	freeze-drying	722:734	arg1	method					736:741	a freeze-drying method	720:741	a freeze-drying method	720:741	The solid foams were prepared by mixing the excipients and clotrimazole via probe sonication, followed by a freeze-drying method.					
35550171	6	9	theme	cationic	945:952	arg1	chitosan					954:961	the cationic chitosan	941:961	the cationic chitosan	941:961	The foam matrix was the PECs between the cationic chitosan and anionic alginate.					
35550171	0	10	dep	release	83:89	arg1	the					79:81	the	79:81	the	79:81	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	8	11	theme	faster	1321:1326	arg1	release					1328:1334	a faster release	1319:1334	a faster release of clotrimazole from the buccal foams	1319:1372	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	4	12	theme	probe	690:694	arg1	sonication					696:705	probe sonication	690:705	probe sonication	690:705	The solid foams were prepared by mixing the excipients and clotrimazole via probe sonication, followed by a freeze-drying method.					
35550171	9	13	dep	%	1479:1479	arg1	GO					1481:1482	GO	1481:1482	GO	1481:1482	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	7	14	theme	drug-free	1061:1069	arg1	foams					1071:1075	drug-free foams	1061:1075	drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate	1061:1211	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	8	15	theme	clotrimazole	1339:1350	arg1	release					1328:1334	a faster release	1319:1334	a faster release of clotrimazole from the buccal foams	1319:1372	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	5	16	theme	other	886:890	arg1	excipients					892:901	the other excipients	882:901	the other excipients	882:901	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	0	17	from	oxide	37:41	arg1	foams					70:74	chitosan/alginate-based foams	46:74	chitosan/alginate-based foams	46:74	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	7	18	dep	clotrimazole	1107:1118	arg1	interacting					1120:1130	interacting	1120:1130	interacting with the anionic alginate	1120:1156	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	7	18	dep	clotrimazole	1107:1118	arg1	interfering					1162:1172	interfering	1162:1172	interfering the PECs between chitosan and alginate	1162:1211	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	2	19	from	composition	313:323	arg1	foams					373:377	chitosan/alginate-based buccal foams	342:377	chitosan/alginate-based buccal foams	342:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	20	theme	buccal	366:371	arg1	foams					373:377	chitosan/alginate-based buccal foams	342:377	chitosan/alginate-based buccal foams	342:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	10	21	dep	amount	1594:1599	arg1	GO					1601:1602	GO	1601:1602	GO in the formulation	1601:1621	A lower amount GO in the formulation may be required for enhancing the antifungal effect, which should be further investigated in future.					
35550171	2	22	theme	oxide	294:298	arg1	effect					275:280	the effect	271:280	the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities	271:431	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	23	theme	chitosan/alginate-based	342:364	arg1	foams					373:377	chitosan/alginate-based buccal foams	342:377	chitosan/alginate-based buccal foams	342:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	5	24	theme	formulations	765:776	arg1	values					751:756	The pH values	744:756	The pH values of the formulations	744:776	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	9	25	theme	clotrimazole-loaded	1545:1563	arg1	foams					1565:1569	clotrimazole-loaded foams	1545:1569	clotrimazole-loaded foams	1545:1569	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	3	26	with	interactions	476:487	arg1	excipients					506:515	excipients	506:515	excipients in the foams	506:528	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	2	27	from	excipients	328:337	arg1	foams					373:377	chitosan/alginate-based buccal foams	342:377	chitosan/alginate-based buccal foams	342:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	28	theme	graphene	285:292	arg1	oxide					294:298	graphene oxide	285:298	graphene oxide (GO)	285:303	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	8	29	theme	GO	1226:1227	arg1	Addition					1214:1221	Addition	1214:1221	Addition of GO in the clotrimazole-loaded matrix	1214:1261	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	2	30	theme	antifungal	411:420	arg1	activities					422:431	antifungal activities	411:431	antifungal activities	411:431	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	8	31	theme	stronger	1291:1298	arg1	foams					1272:1276	the foams	1268:1276	the foams mechanically stronger	1268:1298	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	8	32	theme	clotrimazole-loaded	1236:1254	arg1	matrix					1256:1261	the clotrimazole-loaded matrix	1232:1261	the clotrimazole-loaded matrix	1232:1261	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	7	33	theme	anionic	1141:1147	arg1	alginate					1149:1156	the anionic alginate	1137:1156	the anionic alginate	1137:1156	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	0	34	theme	clotrimazole	118:129	arg1	release					83:89	release	83:89	release	83:89	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	0	34	theme	clotrimazole	118:129	arg1	activity					106:113	antifungal activity	95:113	antifungal activity	95:113	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	9	35	from	addition	1463:1470	arg1	formulations					1491:1502	the formulations	1487:1502	the formulations	1487:1502	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	8	36	theme	buccal	1361:1366	arg1	foams					1368:1372	the buccal foams	1357:1372	the buccal foams	1357:1372	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	8	37	from	matrix	1256:1261	arg1	Addition					1214:1221	Addition	1214:1221	Addition of GO in the clotrimazole-loaded matrix	1214:1261	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	2	38	theme	clotrimazole	386:397	arg1	release					399:405	the clotrimazole release	382:405	the clotrimazole release	382:405	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	0	39	theme	oxide	37:41	arg1	effect					18:23	the effect	14:23	the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole	14:129	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	3	40	theme	various	585:591	arg1	media					593:597	various media	585:597	various media	585:597	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	7	41	theme	foams	1032:1036	arg1	lower					1042:1046	lower	1042:1046	lower	1042:1046	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	7	41	theme	foams	1032:1036	arg1	strength					1000:1007	The mechanical strength	985:1007	The mechanical strength of clotrimazole-loaded foams	985:1036	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	10	42	theme	antifungal	1657:1666	arg1	effect					1668:1673	the antifungal effect	1653:1673	the antifungal effect	1653:1673	A lower amount GO in the formulation may be required for enhancing the antifungal effect, which should be further investigated in future.					
35550171	3	43	theme	degree	561:566	arg1	changes					539:545	the changes	535:545	the changes of ionization degree upon exposure to various media	535:597	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	5	44	theme	foam	803:806	arg1	process					820:826	the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients	799:901	the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients	799:901	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	0	45	theme	graphene	28:35	arg1	oxide					37:41	graphene oxide	28:41	graphene oxide in chitosan/alginate-based foams	28:74	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	5	46	theme	pH	748:749	arg1	values					751:756	The pH values	744:756	The pH values of the formulations	744:776	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	10	47	theme	lower	1588:1592	arg1	amount					1594:1599	A lower amount	1586:1599	A lower amount GO in the formulation	1586:1621	A lower amount GO in the formulation may be required for enhancing the antifungal effect, which should be further investigated in future.					
35550171	5	48	theme	preparation	808:818	arg1	process					820:826	the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients	799:901	the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients	799:901	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	0	49	theme	chitosan/alginate-based	46:68	arg1	foams					70:74	chitosan/alginate-based foams	46:74	chitosan/alginate-based foams	46:74	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	5	50	theme	ionization	844:853	arg1	degree					855:860	the ionization degree	840:860	the ionization degree of clotrimazole	840:876	The pH values of the formulations were measured during the foam preparation process to estimate the ionization degree of clotrimazole and the other excipients.					
35550171	0	51	from	foams	70:74	arg1	effect					18:23	the effect	14:23	the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole	14:129	Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro.					
35550171	8	52	theme	electrostatic	1392:1404	arg1	interactions					1406:1417	the electrostatic interactions	1388:1417	the electrostatic interactions between alginate and clotrimazole	1388:1451	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	9	53	theme	%	1479:1479	arg1	addition					1463:1470	addition	1463:1470	addition of 1 wt% GO in the formulations	1463:1502	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	7	54	theme	clotrimazole-loaded	1012:1030	arg1	foams					1032:1036	clotrimazole-loaded foams	1012:1036	clotrimazole-loaded foams	1012:1036	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	3	55	theme	ionization	550:559	arg1	degree					561:566	ionization degree	550:566	ionization degree	550:566	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	2	56	from	foams	373:377	arg1	composition					313:323	the composition	309:323	the composition of excipients in chitosan/alginate-based buccal foams	309:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	56	from	foams	373:377	arg1	oxide					294:298	graphene oxide	285:298	graphene oxide (GO)	285:303	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	9	57	theme	foams	1565:1569	arg1	activity					1533:1540	the antifungal activity	1518:1540	the antifungal activity of clotrimazole-loaded foams	1518:1569	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	7	58	theme	mechanical	989:998	arg1	lower					1042:1046	lower	1042:1046	lower	1042:1046	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	7	58	theme	mechanical	989:998	arg1	strength					1000:1007	The mechanical strength	985:1007	The mechanical strength of clotrimazole-loaded foams	985:1036	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	1	59	theme	Polyelectrolyte	141:155	arg1	complexes					157:165	Polyelectrolyte complexes	141:165	Polyelectrolyte complexes (PECs)	141:172	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	59	theme	Polyelectrolyte	141:155	arg1	matrix					196:201	the matrix	192:201	the matrix of solid foams for drug delivery	192:234	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	59	theme	Polyelectrolyte	141:155	arg1	PECs					168:171	PECs	168:171	PECs	168:171	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	60	used	used	184:187	arg2	PECs					168:171	PECs	168:171	PECs	168:171	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	60	used	used	184:187	arg2	complexes					157:165	Polyelectrolyte complexes	141:165	Polyelectrolyte complexes (PECs)	141:172	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	60	used	used	184:187	arg2	matrix					196:201	the matrix	192:201	the matrix of solid foams for drug delivery	192:234	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	8	61	from	Addition	1214:1221	arg1	matrix					1256:1261	the clotrimazole-loaded matrix	1232:1261	the clotrimazole-loaded matrix	1232:1261	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	2	62	dep	oxide	294:298	arg1	GO					301:302	GO	301:302	GO	301:302	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	1	63	theme	solid	206:210	arg1	foams					212:216	solid foams	206:216	solid foams for drug delivery	206:234	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	6	64	theme	foam	908:911	arg1	matrix					913:918	The foam matrix	904:918	The foam matrix	904:918	The foam matrix was the PECs between the cationic chitosan and anionic alginate.					
35550171	6	64	theme	foam	908:911	arg1	PECs					928:931	the PECs	924:931	the PECs between the cationic chitosan and anionic alginate	924:982	The foam matrix was the PECs between the cationic chitosan and anionic alginate.					
35550171	1	65	theme	foams	212:216	arg1	complexes					157:165	Polyelectrolyte complexes	141:165	Polyelectrolyte complexes (PECs)	141:172	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	1	65	theme	foams	212:216	arg1	matrix					196:201	the matrix	192:201	the matrix of solid foams for drug delivery	192:234	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35550171	9	66	theme	wt	1477:1478	arg1	%					1479:1479	1 wt% GO	1475:1482	1 wt% GO	1475:1482	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	8	67	from	foams	1368:1372	arg1	release					1328:1334	a faster release	1319:1334	a faster release of clotrimazole from the buccal foams	1319:1372	Addition of GO in the clotrimazole-loaded matrix made the foams mechanically stronger and contributed to a faster release of clotrimazole from the buccal foams by disrupting the electrostatic interactions between alginate and clotrimazole.					
35550171	2	68	theme	excipients	328:337	arg1	composition					313:323	the composition	309:323	the composition of excipients in chitosan/alginate-based buccal foams	309:377	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	2	68	theme	excipients	328:337	arg1	oxide					294:298	graphene oxide	285:298	graphene oxide (GO)	285:303	This study aimed at investigating the effect of graphene oxide (GO) and the composition of excipients in chitosan/alginate-based buccal foams on the clotrimazole release and antifungal activities.					
35550171	4	69	theme	solid	618:622	arg1	foams					624:628	The solid foams	614:628	The solid foams	614:628	The solid foams were prepared by mixing the excipients and clotrimazole via probe sonication, followed by a freeze-drying method.					
35550171	9	70	theme	antifungal	1522:1531	arg1	activity					1533:1540	the antifungal activity	1518:1540	the antifungal activity of clotrimazole-loaded foams	1518:1569	However, addition of 1 wt% GO in the formulations didn't affect the antifungal activity of clotrimazole-loaded foams significantly.					
35550171	7	71	theme	charged	1099:1105	arg1	clotrimazole					1107:1118	the positively charged clotrimazole	1084:1118	the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate	1084:1211	The mechanical strength of clotrimazole-loaded foams was lower than that of drug-free foams due to the positively charged clotrimazole interacting with the anionic alginate and interfering the PECs between chitosan and alginate.					
35550171	6	72	theme	anionic	967:973	arg1	alginate					975:982	anionic alginate	967:982	anionic alginate	967:982	The foam matrix was the PECs between the cationic chitosan and anionic alginate.					
35550171	3	73	from	excipients	506:515	arg1	foams					524:528	the foams	520:528	the foams	520:528	The investigation has been focused on the interactions of the drug with excipients in the foams, and the changes of ionization degree upon exposure to various media are discussed.					
35550171	1	74	theme	drug	222:225	arg1	delivery					227:234	drug delivery	222:234	drug delivery	222:234	Polyelectrolyte complexes (PECs) have been used as the matrix of solid foams for drug delivery.					
35715472	11	0	theme	improved	1334:1341	arg1	ratio					1352:1356	improved swelling ratio	1334:1356	improved swelling ratio	1334:1356	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	11	1	theme	swelling	1343:1350	arg1	ratio					1352:1356	improved swelling ratio	1334:1356	improved swelling ratio	1334:1356	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	6	2	theme	drying	783:788	arg1	method					790:795	freeze drying method	776:795	freeze drying method	776:795	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	7	3	theme	zeta	854:857	arg1	XRD					872:874	zeta sizer, FTIR, XRD,	854:875	XRD	872:874	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	7	3	theme	zeta	854:857	arg1	FE					878:879	FE	878:879	FE	878:879	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	14	4	theme	Alg/Cs/Sr-BG20	1771:1784	arg1	scaffold					1786:1793	Alg/Cs/Sr-BG20 scaffold	1771:1793	Alg/Cs/Sr-BG20 scaffold	1771:1793	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	12	5	theme	differentiation	1434:1448	arg1	efficiency					1450:1459	Mechanical strength and cell differentiation efficiency	1405:1459	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold	1405:1483	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	8	6	theme	mechanical	901:910	arg1	strength					912:919	mechanical strength	901:919	mechanical strength	901:919	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	11	7	theme	cell	1383:1386	arg1	differentiation					1388:1402	cell differentiation	1383:1402	cell differentiation	1383:1402	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	4	8	theme	optimized	461:469	arg1	properties					471:480	optimized properties	461:480	optimized properties	461:480	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	13	9	with	comparison	1658:1667	arg1	Alg/Cs					1674:1679	Alg/Cs	1674:1679	Alg/Cs	1674:1679	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	13	9	with	comparison	1658:1667	arg1	scaffolds					1695:1703	Alg/Cs/BG scaffolds	1685:1703	Alg/Cs/BG scaffolds	1685:1703	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	15	10	theme	scaffolds	1900:1908	arg1	Biomineralization					1869:1885	Biomineralization	1869:1885	Biomineralization of Alg/Cs/BG scaffolds	1869:1908	Biomineralization of Alg/Cs/BG scaffolds slightly was higher than Alg/Cs/Sr-BG scaffolds.					
35715472	13	11	theme	differentiation	1628:1642	arg1	efficiency					1644:1653	more differentiation efficiency	1623:1653	more differentiation efficiency	1623:1653	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	7	12	theme	bioglasses/scaffolds	818:837	arg1	Characterization					798:813	Characterization	798:813	Characterization of bioglasses/scaffolds	798:837	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	12	13	theme	Mechanical	1405:1414	arg1	efficiency					1450:1459	Mechanical strength and cell differentiation efficiency	1405:1459	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold	1405:1483	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	8	14	theme	effect	936:941	arg1	degradation					943:953	antibacterial effect degradation	922:953	antibacterial effect degradation	922:953	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	4	15	theme	bioglass	427:434	arg1	scaffolds					446:454	chitosan/alginate/strontium-doped bioglass composite scaffolds	393:454	chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering	393:508	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	14	16	theme	differentiation	1741:1755	arg1	efficiency					1757:1766	Mechanical strength and cell differentiation efficiency	1712:1766	Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold	1712:1793	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	13	17	theme	mechanical	1598:1607	arg1	stability					1609:1617	higher mechanical stability	1591:1617	higher mechanical stability	1591:1617	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	5	18	theme	Sr-doped	529:536	arg1	Sr-BG					550:554	Sr-BG	550:554	Sr-BG	550:554	Bioglass (BG) and Sr-doped bioglasses (Sr-BG) were synthesized using Sol-Gel method.					
35715472	5	18	theme	Sr-doped	529:536	arg1	bioglasses					538:547	Sr-doped bioglasses	529:547	Sr-doped bioglasses (Sr-BG)	529:555	Bioglass (BG) and Sr-doped bioglasses (Sr-BG) were synthesized using Sol-Gel method.					
35715472	14	19	with	scaffolds	1824:1832	arg1	concentrations					1853:1866	various Sr-BG concentrations	1839:1866	various Sr-BG concentrations	1839:1866	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	2	20	theme	tissue	239:244	arg1	engineering					246:256	tissue engineering	239:256	tissue engineering using 3D scaffolds	239:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	16	21	theme	Alg/Cs/Sr-BG20	1986:1999	arg1	scaffolds					2001:2009	Alg/Cs/Sr-BG20 scaffolds	1986:2009	Alg/Cs/Sr-BG20 scaffolds	1986:2009	Overall, we concluded that Alg/Cs/Sr-BG20 scaffolds are more suitable for repairing bone major injuries.					
35715472	3	22	theme	materials	323:331	arg1	Incorporation					291:303	Incorporation	291:303	Incorporation of some bioactive materials and trace elements	291:350	Incorporation of some bioactive materials and trace elements can improve scaffold properties.					
35715472	14	23	theme	Mechanical	1712:1721	arg1	efficiency					1757:1766	Mechanical strength and cell differentiation efficiency	1712:1766	Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold	1712:1793	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	13	24	theme	Alg/Cs/Sr-BG	1564:1575	arg1	scaffolds					1577:1585	Alg/Cs/Sr-BG scaffolds	1564:1585	Alg/Cs/Sr-BG scaffolds	1564:1585	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	7	25	dep	XRD	872:874	arg1	SEM					882:884	SEM	882:884	SEM	882:884	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	7	25	dep	XRD	872:874	arg1	FTIR					866:869	zeta sizer, FTIR, XRD,	854:875	FTIR	866:869	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	1	26	theme	important	141:149	arg1	Repairing					102:110	Repairing	102:110	Repairing of large bone injuries	102:133	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	1	26	theme	important	141:149	arg1	problem					151:157	an important problem	138:157	an important problem in bone regeneration field	138:184	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	12	27	theme	BG	1545:1546	arg1	concentrations					1548:1561	lower or higher BG concentrations	1529:1561	lower or higher BG concentrations	1529:1561	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	12	28	with	scaffolds	1514:1522	arg1	concentrations					1548:1561	lower or higher BG concentrations	1529:1561	lower or higher BG concentrations	1529:1561	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	4	29	theme	tissue	491:496	arg1	engineering					498:508	bone tissue engineering	486:508	bone tissue engineering	486:508	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	10	30	theme	bioglasses	1168:1177	arg1	toxicity					1131:1138	Cell toxicity	1126:1138	Cell toxicity	1126:1138	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	10	30	theme	bioglasses	1168:1177	arg1	effect					1158:1163	antibacterial effect	1144:1163	antibacterial effect of bioglasses	1144:1177	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	0	31	theme	bone	76:79	arg1	regeneration					88:99	amplified bone tissue regeneration	66:99	amplified bone tissue regeneration	66:99	Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration.					
35715472	5	32	theme	Sol-Gel	580:586	arg1	method					588:593	Sol-Gel method	580:593	Sol-Gel method	580:593	Bioglass (BG) and Sr-doped bioglasses (Sr-BG) were synthesized using Sol-Gel method.					
35715472	3	33	theme	trace	337:341	arg1	elements					343:350	trace elements	337:350	trace elements	337:350	Incorporation of some bioactive materials and trace elements can improve scaffold properties.					
35715472	3	34	theme	bioactive	313:321	arg1	materials					323:331	some bioactive materials	308:331	some bioactive materials	308:331	Incorporation of some bioactive materials and trace elements can improve scaffold properties.					
35715472	10	35	theme	MIC	1206:1208	arg1	methods					1218:1224	MTT, MIC and MBC methods	1201:1224	MTT, MIC and MBC methods	1201:1224	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	1	36	theme	regeneration	167:178	arg1	field					180:184	bone regeneration field	162:184	bone regeneration field	162:184	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	10	37	theme	MTT	1201:1203	arg1	methods					1218:1224	MTT, MIC and MBC methods	1201:1224	MTT, MIC and MBC methods	1201:1224	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	8	38	theme	scaffolds	979:987	arg1	degradation					943:953	antibacterial effect degradation	922:953	antibacterial effect degradation	922:953	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	8	38	theme	scaffolds	979:987	arg1	profile					968:974	swelling profile	959:974	swelling profile	959:974	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	8	38	theme	scaffolds	979:987	arg1	strength					912:919	mechanical strength	901:919	mechanical strength	901:919	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	1	39	from	problem	151:157	arg1	field					180:184	bone regeneration field	162:184	bone regeneration field	162:184	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	3	40	theme	scaffold	364:371	arg1	properties					373:382	scaffold properties	364:382	scaffold properties	364:382	Incorporation of some bioactive materials and trace elements can improve scaffold properties.					
35715472	6	41	dep	BG	695:696	arg1	30					716:717	30	716:717	30	716:717	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	15	42	theme	Alg/Cs/BG	1890:1898	arg1	scaffolds					1900:1908	Alg/Cs/BG scaffolds	1890:1908	Alg/Cs/BG scaffolds	1890:1908	Biomineralization of Alg/Cs/BG scaffolds slightly was higher than Alg/Cs/Sr-BG scaffolds.					
35715472	10	43	theme	MBC	1214:1216	arg1	methods					1218:1224	MTT, MIC and MBC methods	1201:1224	MTT, MIC and MBC methods	1201:1224	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	6	44	theme	BG	695:696	arg1	ratio					667:671	different ratio	657:671	different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30)	657:752	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	1	45	theme	bone	121:124	arg1	injuries					126:133	large bone injuries	115:133	large bone injuries	115:133	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	13	46	theme	Alg/Cs/BG	1685:1693	arg1	scaffolds					1695:1703	Alg/Cs/BG scaffolds	1685:1703	Alg/Cs/BG scaffolds	1685:1703	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	0	47	theme	hydrogel-based	38:51	arg1	scaffold					53:60	incorporated hydrogel-based scaffold	25:60	incorporated hydrogel-based scaffold for amplified bone tissue regeneration	25:99	Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration.					
35715472	14	48	theme	Sr-BG	1847:1851	arg1	concentrations					1853:1866	various Sr-BG concentrations	1839:1866	various Sr-BG concentrations	1839:1866	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	12	49	theme	Alg/Cs/BG20	1464:1474	arg1	scaffold					1476:1483	Alg/Cs/BG20 scaffold	1464:1483	Alg/Cs/BG20 scaffold	1464:1483	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	2	50	theme	therapeutic	208:218	arg1	engineering					246:256	tissue engineering	239:256	tissue engineering using 3D scaffolds	239:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	2	50	theme	therapeutic	208:218	arg1	approaches					220:229	new therapeutic approaches	204:229	new therapeutic approaches such as tissue engineering using 3D scaffolds	204:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	9	51	from	viability	1041:1049	arg1	scaffolds					1062:1070	scaffolds	1062:1070	scaffolds	1062:1070	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	6	52	dep	Sr-BG	723:727	arg1	30					750:751	30	750:751	30	750:751	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	6	53	theme	Alg/Cs	615:620	arg1	scaffold					623:630	Alginate-Chitosan (Alg/Cs) scaffold	596:630	Alginate-Chitosan (Alg/Cs) scaffold	596:630	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	9	54	from	efficiency	1026:1035	arg1	scaffolds					1062:1070	scaffolds	1062:1070	scaffolds	1062:1070	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	13	55	contain	had	1587:1589	arg2	efficiency					1644:1653	more differentiation efficiency	1623:1653	more differentiation efficiency	1623:1653	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	13	55	contain	had	1587:1589	arg1	scaffolds					1577:1585	Alg/Cs/Sr-BG scaffolds	1564:1585	Alg/Cs/Sr-BG scaffolds	1564:1585	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	13	55	contain	had	1587:1589	arg2	stability					1609:1617	higher mechanical stability	1591:1617	higher mechanical stability	1591:1617	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	12	56	theme	cell	1429:1432	arg1	differentiation					1434:1448	cell differentiation	1429:1448	cell differentiation	1429:1448	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	16	57	theme	major	2048:2052	arg1	injuries					2054:2061	bone major injuries	2043:2061	bone major injuries	2043:2061	Overall, we concluded that Alg/Cs/Sr-BG20 scaffolds are more suitable for repairing bone major injuries.					
35715472	6	58	theme	Alginate-Chitosan	596:612	arg1	scaffold					623:630	Alginate-Chitosan (Alg/Cs) scaffold	596:630	Alginate-Chitosan (Alg/Cs) scaffold	596:630	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	14	59	theme	scaffold	1786:1793	arg1	efficiency					1757:1766	Mechanical strength and cell differentiation efficiency	1712:1766	Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold	1712:1793	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	6	60	theme	freeze	776:781	arg1	method					790:795	freeze drying method	776:795	freeze drying method	776:795	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	7	61	theme	sizer	859:863	arg1	XRD					872:874	zeta sizer, FTIR, XRD,	854:875	XRD	872:874	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	7	61	theme	sizer	859:863	arg1	FE					878:879	FE	878:879	FE	878:879	Characterization of bioglasses/scaffolds was done using zeta sizer, FTIR, XRD, (FE) SEM and EDS.					
35715472	10	62	theme	antibacterial	1144:1156	arg1	effect					1158:1163	antibacterial effect	1144:1163	antibacterial effect of bioglasses	1144:1177	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	8	63	theme	antibacterial	922:934	arg1	degradation					943:953	antibacterial effect degradation	922:953	antibacterial effect degradation	922:953	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	11	64	theme	degradation	1359:1369	arg1	profile					1371:1377	degradation profile	1359:1377	degradation profile	1359:1377	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	12	65	theme	strength	1416:1423	arg1	efficiency					1450:1459	Mechanical strength and cell differentiation efficiency	1405:1459	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold	1405:1483	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	4	66	theme	chitosan/alginate/strontium-doped	393:425	arg1	scaffolds					446:454	chitosan/alginate/strontium-doped bioglass composite scaffolds	393:454	chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering	393:508	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	4	67	theme	composite	436:444	arg1	scaffolds					446:454	chitosan/alginate/strontium-doped bioglass composite scaffolds	393:454	chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering	393:508	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	6	68	theme	different	657:665	arg1	ratio					667:671	different ratio	657:671	different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30)	657:752	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	8	69	theme	swelling	959:966	arg1	profile					968:974	swelling profile	959:974	swelling profile	959:974	Also, mechanical strength, antibacterial effect degradation and swelling profile of scaffolds were evaluated.					
35715472	13	70	theme	higher	1591:1596	arg1	stability					1609:1617	higher mechanical stability	1591:1617	higher mechanical stability	1591:1617	Alg/Cs/Sr-BG scaffolds had higher mechanical stability and more differentiation efficiency in comparison with Alg/Cs and Alg/Cs/BG scaffolds.					
35715472	14	71	theme	cell	1736:1739	arg1	differentiation					1741:1755	cell differentiation	1736:1755	cell differentiation	1736:1755	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	6	72	contain	containing	646:655	arg1	scaffolds					636:644	scaffolds	636:644	scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30)	636:752	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	6	72	contain	containing	646:655	arg2	ratio					667:671	different ratio	657:671	different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30)	657:752	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	11	73	theme	mechanical	1301:1310	arg1	properties					1312:1321	mechanical properties	1301:1321	mechanical properties	1301:1321	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	14	74	theme	strength	1723:1730	arg1	efficiency					1757:1766	Mechanical strength and cell differentiation efficiency	1712:1766	Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold	1712:1793	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	1	75	theme	injuries	126:133	arg1	problem					151:157	an important problem	138:157	an important problem in bone regeneration field	138:184	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	1	75	theme	injuries	126:133	arg1	Repairing					102:110	Repairing	102:110	Repairing of large bone injuries	102:133	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	4	76	theme	bone	486:489	arg1	engineering					498:508	bone tissue engineering	486:508	bone tissue engineering	486:508	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	6	77	dep	ratio	667:671	arg1	%					676:676	10%	674:676	10%	674:676	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	6	77	dep	ratio	667:671	arg1	%					681:681	20%	679:681	20%	679:681	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	6	77	dep	ratio	667:671	arg1	%					689:689	30%	687:689	30%	687:689	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	0	78	theme	tissue	81:86	arg1	regeneration					88:99	amplified bone tissue regeneration	66:99	amplified bone tissue regeneration	66:99	Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration.					
35715472	9	79	theme	differentiation	1010:1024	arg1	efficiency					1026:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	2	80	theme	3D	264:265	arg1	scaffolds					267:275	3D scaffolds	264:275	3D scaffolds	264:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	1	81	theme	bone	162:165	arg1	field					180:184	bone regeneration field	162:184	bone regeneration field	162:184	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	12	82	theme	lower	1529:1533	arg1	concentrations					1548:1561	lower or higher BG concentrations	1529:1561	lower or higher BG concentrations	1529:1561	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	3	83	theme	elements	343:350	arg1	Incorporation					291:303	Incorporation	291:303	Incorporation of some bioactive materials and trace elements	291:350	Incorporation of some bioactive materials and trace elements can improve scaffold properties.					
35715472	9	84	theme	Bone	1005:1008	arg1	efficiency					1026:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	12	85	theme	higher	1538:1543	arg1	concentrations					1548:1561	lower or higher BG concentrations	1529:1561	lower or higher BG concentrations	1529:1561	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
35715472	9	86	dep	Red	1100:1102	arg1	methods					1117:1123	methods	1117:1123	methods	1117:1123	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	11	87	theme	Alg/Cs	1252:1257	arg1	scaffolds					1259:1267	Alg/Cs scaffolds	1252:1267	Alg/Cs scaffolds	1252:1267	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	15	88	theme	Alg/Cs/Sr-BG	1935:1946	arg1	scaffolds					1948:1956	Alg/Cs/Sr-BG scaffolds	1935:1956	Alg/Cs/Sr-BG scaffolds	1935:1956	Biomineralization of Alg/Cs/BG scaffolds slightly was higher than Alg/Cs/Sr-BG scaffolds.					
35715472	11	89	theme	BG	1244:1245	arg1	Incorporation					1227:1239	Incorporation	1227:1239	Incorporation of BG into Alg/Cs scaffolds	1227:1267	Incorporation of BG into Alg/Cs scaffolds amplified biomineralization and mechanical properties along with improved swelling ratio, degradation profile and cell differentiation.					
35715472	9	90	theme	MSCs	1054:1057	arg1	viability					1041:1049	viability	1041:1049	viability	1041:1049	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	9	90	theme	MSCs	1054:1057	arg1	efficiency					1026:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency	1005:1035	Bone differentiation efficiency and viability of MSCs on scaffolds were determined by Alizarin Red, ALP and MTT methods.					
35715472	0	91	theme	incorporated	25:36	arg1	scaffold					53:60	incorporated hydrogel-based scaffold	25:60	incorporated hydrogel-based scaffold for amplified bone tissue regeneration	25:99	Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration.					
35715472	1	92	theme	large	115:119	arg1	injuries					126:133	large bone injuries	115:133	large bone injuries	115:133	Repairing of large bone injuries is an important problem in bone regeneration field.					
35715472	4	93	with	scaffolds	446:454	arg1	properties					471:480	optimized properties	461:480	optimized properties	461:480	We made chitosan/alginate/strontium-doped bioglass composite scaffolds with optimized properties for bone tissue engineering.					
35715472	0	94	theme	amplified	66:74	arg1	regeneration					88:99	amplified bone tissue regeneration	66:99	amplified bone tissue regeneration	66:99	Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration.					
35715472	14	95	theme	various	1839:1845	arg1	concentrations					1853:1866	various Sr-BG concentrations	1839:1866	various Sr-BG concentrations	1839:1866	Also, Mechanical strength and cell differentiation efficiency of Alg/Cs/Sr-BG20 scaffold was considerably higher than scaffolds with various Sr-BG concentrations.					
35715472	16	96	theme	bone	2043:2046	arg1	injuries					2054:2061	bone major injuries	2043:2061	bone major injuries	2043:2061	Overall, we concluded that Alg/Cs/Sr-BG20 scaffolds are more suitable for repairing bone major injuries.					
35715472	2	97	theme	new	204:206	arg1	engineering					246:256	tissue engineering	239:256	tissue engineering using 3D scaffolds	239:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	2	97	theme	new	204:206	arg1	approaches					220:229	new therapeutic approaches	204:229	new therapeutic approaches such as tissue engineering using 3D scaffolds	204:275	Thus, developing new therapeutic approaches such as tissue engineering using 3D scaffolds is necessary.					
35715472	6	98	theme	Sr-BG	723:727	arg1	ratio					667:671	different ratio	657:671	different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30)	657:752	Alginate-Chitosan (Alg/Cs) scaffold and scaffolds containing different ratio (10%, 20% and 30%) of BG (Alg/Cs/BG10, 20, 30) or Sr-BG (Alg/Cs/Sr-BG10, 20, 30) were fabricated using freeze drying method.					
35715472	10	99	theme	Cell	1126:1129	arg1	toxicity					1131:1138	Cell toxicity	1126:1138	Cell toxicity	1126:1138	Cell toxicity and antibacterial effect of bioglasses were determined using MTT, MIC and MBC methods.					
35715472	12	100	theme	scaffold	1476:1483	arg1	efficiency					1450:1459	Mechanical strength and cell differentiation efficiency	1405:1459	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold	1405:1483	Mechanical strength and cell differentiation efficiency of Alg/Cs/BG20 scaffold was considerably higher than scaffolds with lower or higher BG concentrations.					
36198366	11	0	theme	kinetic	1494:1500	arg1	energy					1513:1518	a kinetic activation energy	1492:1518	a kinetic activation energy of 67.99 kJ/mol	1492:1534	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	10	1	theme	tensile	1278:1284	arg1	665 ± 7 MPa					1299:1309	665 ± 7 MPa	1299:1309	665 ± 7 MPa	1299:1309	The single fibre tensile test revealed that the tensile strength was 665 ± 7 MPa and Young's modulus was 27.45 ± 3.46 GPa.					
36198366	10	1	theme	tensile	1278:1284	arg1	strength					1286:1293	the tensile strength	1274:1293	the tensile strength	1274:1293	The single fibre tensile test revealed that the tensile strength was 665 ± 7 MPa and Young's modulus was 27.45 ± 3.46 GPa.					
36198366	4	2	theme	matrix	588:593	arg1	composites					595:604	polymer matrix composites	580:604	polymer matrix composites	580:604	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	9	3	theme	cellulose	1100:1108	arg1	presence					1088:1095	The presence	1084:1095	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs	1084:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	6	4	theme	0.23 wt	836:842	arg1	%					843:843	0.23 wt%	836:843	0.23 wt%	836:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	11	5	theme	67.99 kJ/mol	1523:1534	arg1	energy					1513:1518	a kinetic activation energy	1492:1518	a kinetic activation energy of 67.99 kJ/mol	1492:1534	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	9	6	theme	peak	1113:1116	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	12	7	theme	force	1596:1600	arg1	AFM					1614:1616	AFM	1614:1616	AFM	1614:1616	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	12	7	theme	force	1596:1600	arg1	microscopy					1602:1611	atomic force microscopy	1589:1611	atomic force microscopy (AFM)	1589:1617	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	6	8	theme	hemicellulose	750:762	arg1	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	0	9	from	grass	87:91	arg1	characterization					15:30	characterization	15:30	characterization	15:30	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	0	9	from	grass	87:91	arg1	Extraction					0:9	Extraction	0:9	Extraction	0:9	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	7	10	theme	diffraction	936:946	arg1	analysis					954:961	X-ray diffraction (XRD) analysis	930:961	X-ray diffraction (XRD) analysis	930:961	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	3	11	theme	natural	296:302	arg1	fibres					320:325	natural lignocellulosic fibres	296:325	natural lignocellulosic fibres	296:325	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	3	11	theme	natural	296:302	arg1	material					353:360	a reinforcing material	339:360	a reinforcing material	339:360	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	13	12	contain	have	1698:1701	arg1	TAFs					1693:1696	the TAFs	1689:1696	the TAFs	1689:1696	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	13	12	contain	have	1698:1701	arg1	reinforcement					1816:1828	the possible reinforcement	1803:1828	the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites	1803:1888	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	13	12	contain	have	1698:1701	arg2	properties					1713:1722	desirable properties	1703:1722	desirable properties that are comparable to existing natural fibres	1703:1769	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	6	13	theme	Chemical	649:656	arg1	analysis					658:665	Chemical analysis	649:665	Chemical analysis	649:665	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	14	theme	T.	682:683	arg1	TAFs					703:706	TAFs	703:706	TAFs	703:706	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	14	theme	T.	682:683	arg1	fibres					695:700	T. angustata fibres	682:700	T. angustata fibres (TAFs)	682:707	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	12	15	theme	atomic	1589:1594	arg1	AFM					1614:1616	AFM	1614:1616	AFM	1614:1616	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	12	15	theme	atomic	1589:1594	arg1	microscopy					1602:1611	atomic force microscopy	1589:1611	atomic force microscopy (AFM)	1589:1617	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	11	16	theme	TAFs	1382:1385	arg1	stability					1365:1373	The thermal stability	1353:1373	The thermal stability of the TAFs	1353:1385	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	0	17	theme	Typha	71:75	arg1	grass					87:91	Typha angustata grass	71:91	Typha angustata grass	71:91	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	11	18	theme	thermogravimetric	1403:1419	arg1	TGA					1431:1433	TGA	1431:1433	TGA	1431:1433	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	11	18	theme	thermogravimetric	1403:1419	arg1	analysis					1421:1428	thermogravimetric analysis	1403:1428	thermogravimetric analysis (TGA)	1403:1434	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	9	19	theme	13C	1179:1181	arg1	spectroscopy					1216:1227	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	12	20	theme	fibres	1566:1571	arg1	roughness					1549:1557	The surface roughness	1537:1557	The surface roughness of the fibres	1537:1571	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	6	21	theme	%	783:783	arg1	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	21	theme	%	783:783	arg1	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	21	theme	%	783:783	arg1	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	21	theme	%	783:783	arg1	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	9	22	theme	magnetic	1191:1198	arg1	resonance					1200:1208	nuclear magnetic resonance	1183:1208	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	22	theme	magnetic	1191:1198	arg1	NMR					1211:1213	NMR	1211:1213	NMR	1211:1213	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	3	23	used	used	331:334	arg2	fibres					320:325	natural lignocellulosic fibres	296:325	natural lignocellulosic fibres	296:325	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	3	23	used	used	331:334	arg2	material					353:360	a reinforcing material	339:360	a reinforcing material	339:360	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	4	24	from	reinforcement	563:575	arg1	composites					595:604	polymer matrix composites	580:604	polymer matrix composites	580:604	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	12	25	theme	surface	1541:1547	arg1	roughness					1549:1557	The surface roughness	1537:1557	The surface roughness of the fibres	1537:1571	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	3	26	theme	scientific	419:428	arg1	community					430:438	the scientific community	415:438	the scientific community	415:438	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	1	27	theme	recent	97:102	arg1	years					104:108	recent years	97:108	recent years	97:108	In recent years, efforts have been made to reduce deforestation to conserve the ecosystem.					
36198366	4	28	theme	Typha	538:542	arg1	grass					554:558	Typha angustata grass	538:558	Typha angustata grass	538:558	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	11	29	theme	thermal	1357:1363	arg1	stability					1365:1373	The thermal stability	1353:1373	The thermal stability of the TAFs	1353:1385	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	8	30	theme	groups	991:996	arg1	presence					968:975	The presence	964:975	The presence of functional groups in the TAFs	964:1008	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	6	31	theme	wax	821:823	arg1	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	8	32	attach	presence	968:975	arg2	groups					991:996	functional groups	980:996	functional groups	980:996	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	8	32	attach	presence	968:975	arg1	TAFs					1005:1008	the TAFs	1001:1008	the TAFs	1001:1008	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	6	33	contain	have	709:712	arg2	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	33	contain	have	709:712	arg1	TAFs					703:706	TAFs	703:706	TAFs	703:706	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	33	contain	have	709:712	arg2	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	33	contain	have	709:712	arg2	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	33	contain	have	709:712	arg2	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	33	contain	have	709:712	arg1	fibres					695:700	T. angustata fibres	682:700	T. angustata fibres (TAFs)	682:707	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	13	34	theme	desirable	1703:1711	arg1	properties					1713:1722	desirable properties	1703:1722	desirable properties that are comparable to existing natural fibres	1703:1769	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	3	35	theme	past	451:454	arg1	decades					460:466	the past few decades	447:466	the past few decades	447:466	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	0	36	theme	natural	35:41	arg1	fibres					59:64	natural lignocellulosic fibres	35:64	natural lignocellulosic fibres	35:64	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	4	37	theme	natural	508:514	arg1	fibres					516:521	natural fibres	508:521	natural fibres extracted from Typha angustata grass	508:558	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	6	38	theme	%	745:745	arg1	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	38	theme	%	745:745	arg1	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	38	theme	%	745:745	arg1	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	38	theme	%	745:745	arg1	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	0	39	theme	fibres	59:64	arg1	characterization					15:30	characterization	15:30	characterization	15:30	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	0	39	theme	fibres	59:64	arg1	Extraction					0:9	Extraction	0:9	Extraction	0:9	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	6	40	theme	6.23 wt	806:812	arg1	%					813:813	6.23 wt%	806:813	6.23 wt%	806:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	2	41	theme	current	192:198	arg1	scenario					200:207	the current scenario	188:207	the current scenario	188:207	In the current scenario, agro-cultivated products are used instead of wood for engineering applications.					
36198366	12	42	theme	1 nm	1639:1642	arg1	accuracy					1627:1634	an accuracy	1624:1634	an accuracy of 1 nm	1624:1642	The surface roughness of the fibres was analysed by atomic force microscopy (AFM) with an accuracy of 1 nm.					
36198366	13	43	theme	above-mentioned	1649:1663	arg1	outcomes					1665:1672	The above-mentioned outcomes	1645:1672	The above-mentioned outcomes	1645:1672	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	10	44	theme	tensile	1247:1253	arg1	test					1255:1258	The single fibre tensile test	1230:1258	The single fibre tensile test	1230:1258	The single fibre tensile test revealed that the tensile strength was 665 ± 7 MPa and Young's modulus was 27.45 ± 3.46 GPa.					
36198366	8	45	theme	Fourier-transform	1036:1052	arg1	spectroscopy					1063:1074	Fourier-transform infrared spectroscopy	1036:1074	Fourier-transform infrared spectroscopy (FTIR)	1036:1081	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	8	45	theme	Fourier-transform	1036:1052	arg1	FTIR					1077:1080	FTIR	1077:1080	FTIR	1077:1080	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	10	46	theme	single	1234:1239	arg1	test					1255:1258	The single fibre tensile test	1230:1258	The single fibre tensile test	1230:1258	The single fibre tensile test revealed that the tensile strength was 665 ± 7 MPa and Young's modulus was 27.45 ± 3.46 GPa.					
36198366	11	47	theme	activation	1502:1511	arg1	energy					1513:1518	a kinetic activation energy	1492:1518	a kinetic activation energy of 67.99 kJ/mol	1492:1534	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	9	48	from	C5	1144:1145	arg1	TAFs					1154:1157	the TAFs	1150:1157	the TAFs	1150:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	6	49	theme	%	843:843	arg1	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	49	theme	%	843:843	arg1	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	49	theme	%	843:843	arg1	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	49	theme	%	843:843	arg1	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	2	50	used	used	239:242	arg2	products					226:233	agro-cultivated products	210:233	agro-cultivated products	210:233	In the current scenario, agro-cultivated products are used instead of wood for engineering applications.					
36198366	4	51	theme	polymer	580:586	arg1	composites					595:604	polymer matrix composites	580:604	polymer matrix composites	580:604	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	6	52	theme	10.11 wt	775:782	arg1	%					783:783	10.11 wt%	775:783	10.11 wt%	775:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	2	53	theme	engineering	264:274	arg1	applications					276:287	engineering applications	264:287	engineering applications	264:287	In the current scenario, agro-cultivated products are used instead of wood for engineering applications.					
36198366	9	54	from	C3	1137:1138	arg1	TAFs					1154:1157	the TAFs	1150:1157	the TAFs	1150:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	5	55	theme	fibres	626:631	arg1	1.015 g/cc					637:646	1.015 g/cc	637:646	1.015 g/cc	637:646	The density of the fibres was 1.015 g/cc.					
36198366	5	55	theme	fibres	626:631	arg1	density					611:617	The density	607:617	The density of the fibres	607:631	The density of the fibres was 1.015 g/cc.					
36198366	11	56	theme	prominent	1445:1453	arg1	peak					1455:1458	the prominent peak	1441:1458	the prominent peak	1441:1458	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	9	57	theme	C2	1133:1134	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	13	58	theme	polymer	1864:1870	arg1	composites					1879:1888	the fibre-reinforced polymer matrix composites	1843:1888	the fibre-reinforced polymer matrix composites	1843:1888	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	9	59	theme	C3	1137:1138	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	60	theme	C5	1144:1145	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	2	61	theme	agro-cultivated	210:224	arg1	products					226:233	agro-cultivated products	210:233	agro-cultivated products	210:233	In the current scenario, agro-cultivated products are used instead of wood for engineering applications.					
36198366	8	62	from	presence	968:975	arg1	TAFs					1005:1008	the TAFs	1001:1008	the TAFs	1001:1008	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	3	63	theme	lignocellulosic	304:318	arg1	fibres					320:325	natural lignocellulosic fibres	296:325	natural lignocellulosic fibres	296:325	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	3	63	theme	lignocellulosic	304:318	arg1	material					353:360	a reinforcing material	339:360	a reinforcing material	339:360	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	9	64	from	C2	1133:1134	arg1	TAFs					1154:1157	the TAFs	1150:1157	the TAFs	1150:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	13	65	theme	possible	1807:1814	arg1	TAFs					1693:1696	the TAFs	1689:1696	the TAFs	1689:1696	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	13	65	theme	possible	1807:1814	arg1	reinforcement					1816:1828	the possible reinforcement	1803:1828	the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites	1803:1888	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	7	66	theme	X-ray	930:934	arg1	XRD					949:951	XRD	949:951	XRD	949:951	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	7	66	theme	X-ray	930:934	arg1	diffraction					936:946	X-ray diffraction	930:946	X-ray diffraction (XRD) analysis	930:961	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	9	67	from	intensities	1118:1128	arg1	presence					1088:1095	The presence	1084:1095	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs	1084:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	67	from	intensities	1118:1128	arg1	TAFs					1154:1157	the TAFs	1150:1157	the TAFs	1150:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	0	68	theme	angustata	77:85	arg1	grass					87:91	Typha angustata grass	71:91	Typha angustata grass	71:91	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	13	69	theme	natural	1756:1762	arg1	fibres					1764:1769	existing natural fibres	1747:1769	existing natural fibres	1747:1769	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	11	70	located	observed	1464:1471	arg2	peak					1455:1458	the prominent peak	1441:1458	the prominent peak	1441:1458	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	11	70	located	observed	1464:1471	arg1	298.48 °C					1476:1484	298.48 °C	1476:1484	298.48 °C	1476:1484	The thermal stability of the TAFs was examined by thermogravimetric analysis (TGA), and the prominent peak was observed at 298.48 °C, with a kinetic activation energy of 67.99 kJ/mol.					
36198366	9	71	theme	nuclear	1183:1189	arg1	resonance					1200:1208	nuclear magnetic resonance	1183:1208	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	71	theme	nuclear	1183:1189	arg1	NMR					1211:1213	NMR	1211:1213	NMR	1211:1213	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	72	theme	resonance	1200:1208	arg1	spectroscopy					1216:1227	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	13C nuclear magnetic resonance (NMR) spectroscopy	1179:1227	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	7	73	theme	crystalline	884:894	arg1	6.40 nm					902:908	6.40 nm	902:908	6.40 nm	902:908	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	7	73	theme	crystalline	884:894	arg1	size					896:899	crystalline size	884:899	crystalline size (6.40 nm)	884:909	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	13	74	theme	existing	1747:1754	arg1	fibres					1764:1769	existing natural fibres	1747:1769	existing natural fibres	1747:1769	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	3	75	theme	reinforcing	341:351	arg1	fibres					320:325	natural lignocellulosic fibres	296:325	natural lignocellulosic fibres	296:325	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	3	75	theme	reinforcing	341:351	arg1	material					353:360	a reinforcing material	339:360	a reinforcing material	339:360	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	8	76	theme	functional	980:989	arg1	groups					991:996	functional groups	980:996	functional groups	980:996	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	9	77	from	TAFs	1154:1157	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	4	78	theme	angustata	544:552	arg1	grass					554:558	Typha angustata grass	538:558	Typha angustata grass	538:558	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	6	79	theme	angustata	685:693	arg1	TAFs					703:706	TAFs	703:706	TAFs	703:706	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	79	theme	angustata	685:693	arg1	fibres					695:700	T. angustata fibres	682:700	T. angustata fibres (TAFs)	682:707	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	80	theme	cellulose	716:724	arg1	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	0	81	theme	lignocellulosic	43:57	arg1	fibres					59:64	natural lignocellulosic fibres	35:64	natural lignocellulosic fibres	35:64	Extraction and characterization of natural lignocellulosic fibres from Typha angustata grass.					
36198366	4	82	theme	fibres	516:521	arg1	use					501:503	the use	497:503	the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites	497:604	This study aimed to examine the use of natural fibres extracted from Typha angustata grass as reinforcement in polymer matrix composites.					
36198366	3	83	theme	few	456:458	arg1	decades					460:466	the past few decades	447:466	the past few decades	447:466	Thus, natural lignocellulosic fibres are used as a reinforcing material and have been extremely attractive to industries and the scientific community during the past few decades.					
36198366	6	84	theme	%	813:813	arg1	content					764:770	a hemicellulose content	748:770	a hemicellulose content of 10.11 wt%	748:783	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	84	theme	%	813:813	arg1	content					825:831	a wax content	819:831	a wax content of 0.23 wt%	819:843	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	84	theme	%	813:813	arg1	content					726:732	a cellulose content	714:732	a cellulose content of 73.54 wt%	714:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	84	theme	%	813:813	arg1	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	6	85	theme	73.54 wt	737:744	arg1	%					745:745	73.54 wt%	737:745	73.54 wt%	737:745	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	7	86	theme	crystallinity	850:862	arg1	%					877:877	65.16 %	871:877	65.16 %	871:877	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	7	86	theme	crystallinity	850:862	arg1	index					864:868	The crystallinity index	846:868	The crystallinity index (65.16 %)	846:878	The crystallinity index (65.16 %) and crystalline size (6.40 nm) were identified by X-ray diffraction (XRD) analysis.					
36198366	10	87	theme	fibre	1241:1245	arg1	test					1255:1258	The single fibre tensile test	1230:1258	The single fibre tensile test	1230:1258	The single fibre tensile test revealed that the tensile strength was 665 ± 7 MPa and Young's modulus was 27.45 ± 3.46 GPa.					
36198366	13	88	theme	fibre-reinforced	1847:1862	arg1	composites					1879:1888	the fibre-reinforced polymer matrix composites	1843:1888	the fibre-reinforced polymer matrix composites	1843:1888	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
36198366	9	89	attach	presence	1088:1095	arg1	intensities					1118:1128	peak intensities	1113:1128	peak intensities of C2, C3 and C5 in the TAFs	1113:1157	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	9	89	attach	presence	1088:1095	arg2	cellulose					1100:1108	cellulose	1100:1108	cellulose	1100:1108	The presence of cellulose at peak intensities of C2, C3 and C5 in the TAFs was confirmed using 13C nuclear magnetic resonance (NMR) spectroscopy.					
36198366	8	90	theme	infrared	1054:1061	arg1	spectroscopy					1063:1074	Fourier-transform infrared spectroscopy	1036:1074	Fourier-transform infrared spectroscopy (FTIR)	1036:1081	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	8	90	theme	infrared	1054:1061	arg1	FTIR					1077:1080	FTIR	1077:1080	FTIR	1077:1080	The presence of functional groups in the TAFs was examined by employing Fourier-transform infrared spectroscopy (FTIR).					
36198366	6	91	theme	lignin	788:793	arg1	content					795:801	a lignin content	786:801	a lignin content of 6.23 wt%	786:813	Chemical analysis confirmed that T. angustata fibres (TAFs) have a cellulose content of 73.54 wt%, a hemicellulose content of 10.11 wt%, a lignin content of 6.23 wt% and a wax content of 0.23 wt%.					
36198366	13	92	theme	matrix	1872:1877	arg1	composites					1879:1888	the fibre-reinforced polymer matrix composites	1843:1888	the fibre-reinforced polymer matrix composites	1843:1888	The above-mentioned outcomes indicated that the TAFs have desirable properties that are comparable to existing natural fibres and suggested to be utilised as the possible reinforcement to fabricate the fibre-reinforced polymer matrix composites.					
37379940	4	0	theme	total	972:976	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	0	theme	total	972:976	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	3	1	theme	high	676:679	arg1	value					693:697	its high nutritional value	672:697	its high nutritional value	672:697	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	2	2	theme	water	635:639	arg1	vapor					641:645	water vapor	635:645	water vapor	635:645	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	3	theme	light	625:629	arg1	barrier					611:617	the barrier	607:617	the barrier of UV light and water vapor	607:645	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	3	theme	light	625:629	arg1	stronger					655:662	stronger	655:662	stronger	655:662	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	4	theme	polysaccharide	1569:1582	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	3	5	theme	due	733:735	arg1	life					728:731	a short shelf life	714:731	a short shelf life due to its thin skin and poor storage resistance	714:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	5	6	contain	has	1612:1614	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	6	contain	has	1612:1614	arg2	potential					1623:1631	a high potential	1616:1631	a high potential as a new freshness preservation material for blueberry	1616:1686	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	1	7	theme	solution	183:190	arg1	method					200:205	solution casting method	183:205	solution casting method using chitosan and golden mushroom foot polysaccharide as substrates	183:274	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	5	8	theme	preservation	1594:1605	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	3	9	theme	shelf	722:726	arg1	life					728:731	a short shelf life	714:731	a short shelf life due to its thin skin and poor storage resistance	714:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	4	10	theme	chitosan	884:891	arg1	group					922:926	the uncovered group	908:926	the uncovered group	908:926	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	10	theme	chitosan	884:891	arg1	group					898:902	the single chitosan film group	873:902	the single chitosan film group	873:902	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	10	theme	chitosan	884:891	arg1	controls					941:948	controls	941:948	controls	941:948	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	11	theme	malondialdehyde	1031:1045	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	12	theme	X-ray	404:408	arg1	diffraction					410:420	X-ray diffraction	404:420	X-ray diffraction	404:420	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	4	13	theme	freshness	845:853	arg1	preservation					855:866	freshness preservation	845:866	freshness preservation	845:866	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	3	14	contain	has	710:712	arg2	life					728:731	a short shelf life	714:731	a short shelf life due to its thin skin and poor storage resistance	714:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	3	14	contain	has	710:712	arg1	blueberry					700:708	blueberry	700:708	blueberry	700:708	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	5	15	theme	mushroom	1555:1562	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	2	16	theme	antioxidant	579:589	arg1	properties					591:600	antioxidant properties	579:600	antioxidant properties	579:600	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	1	17	theme	scanning	427:434	arg1	microscopy					445:454	scanning electron microscopy	427:454	scanning electron microscopy	427:454	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	5	18	theme	comprehensive	1213:1225	arg1	results					1227:1233	The comprehensive results	1209:1233	The comprehensive results	1209:1233	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	3	19	theme	poor	758:761	arg1	resistance					771:780	poor storage resistance	758:780	poor storage resistance	758:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	0	20	theme	film	75:78	arg1	Preparation					0:10	Preparation	0:10	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film	0:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	0	20	theme	film	75:78	arg1	application					88:98	its application	84:98	its application in blueberry preservation	84:124	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	1	21	theme	composite	330:338	arg1	film					346:349	the composite cling film	326:349	the composite cling film	326:349	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	22	theme	composite	146:154	arg1	film					162:165	the composite cling film	142:165	the composite cling film	142:165	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	4	23	theme	titratable	1082:1091	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	23	theme	titratable	1082:1091	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	24	theme	film	346:349	arg1	structure					285:293	structure	285:293	structure	285:293	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	24	theme	film	346:349	arg1	indexes					315:321	physicochemical indexes	299:321	physicochemical indexes	299:321	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	0	25	from	Preparation	0:10	arg1	preservation					113:124	blueberry preservation	103:124	blueberry preservation	103:124	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	4	26	theme	blueberry	1138:1146	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	26	theme	blueberry	1138:1146	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	2	27	theme	composite	521:529	arg1	film					537:540	the composite cling film	517:540	the composite cling film	517:540	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	28	theme	antibacterial	1378:1390	arg1	etc.					1428:1431	etc.	1428:1431	etc.	1428:1431	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	28	theme	antibacterial	1378:1390	arg1	properties					1392:1401	better antibacterial properties	1371:1401	better antibacterial properties	1371:1401	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	28	theme	antibacterial	1378:1390	arg1	properties					1416:1425	antioxidant properties	1404:1425	antioxidant properties	1404:1425	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	2	29	theme	vapor	641:645	arg1	barrier					611:617	the barrier	607:617	the barrier of UV light and water vapor	607:645	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	29	theme	vapor	641:645	arg1	stronger					655:662	stronger	655:662	stronger	655:662	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	30	theme	preservation	1261:1272	arg1	higher					1327:1332	higher	1327:1332	higher	1327:1332	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	30	theme	preservation	1261:1272	arg1	effect					1274:1279	the freshness preservation effect	1247:1279	the freshness preservation effect of the composite film group	1247:1307	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	1	31	theme	Fourier	373:379	arg1	spectroscopy					390:401	Fourier infrared spectroscopy	373:401	Fourier infrared spectroscopy	373:401	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	4	32	theme	weight	959:964	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	32	theme	weight	959:964	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	5	33	theme	fruit	1464:1468	arg1	decay					1470:1474	fruit decay	1464:1474	fruit decay	1464:1474	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	0	34	theme	chitosan/Enoki	15:28	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	4	35	used	used	823:826	arg2	object					835:840	the object	831:840	the object of freshness preservation	831:866	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	35	used	used	823:826	arg2	blueberry					809:817	blueberry	809:817	blueberry	809:817	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	0	36	theme	foot	39:42	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	1	37	theme	physicochemical	299:313	arg1	indexes					315:321	physicochemical indexes	299:321	physicochemical indexes	299:321	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	0	38	theme	composite	59:67	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	4	39	theme	freshness	1161:1169	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	39	theme	freshness	1161:1169	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	40	theme	respiration	1008:1018	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	5	41	theme	shelf	1515:1519	arg1	life					1521:1524	the shelf life	1511:1524	the shelf life	1511:1524	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	42	theme	composite	1288:1296	arg1	group					1303:1307	the composite film group	1284:1307	the composite film group	1284:1307	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	43	theme	freshness	1642:1650	arg1	material					1665:1672	a new freshness preservation material	1636:1672	a new freshness preservation material for blueberry	1636:1686	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	1	44	theme	mushroom	233:240	arg1	substrates					265:274	substrates	265:274	substrates	265:274	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	44	theme	mushroom	233:240	arg1	polysaccharide					247:260	golden mushroom foot polysaccharide	226:260	golden mushroom foot polysaccharide	226:260	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	44	theme	mushroom	233:240	arg1	chitosan					213:220	chitosan	213:220	chitosan	213:220	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	3	45	theme	storage	763:769	arg1	resistance					771:780	poor storage resistance	758:780	poor storage resistance	758:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	4	46	theme	bacterial	978:986	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	46	theme	bacterial	978:986	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	5	47	theme	group	1303:1307	arg1	higher					1327:1332	higher	1327:1332	higher	1327:1332	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	47	theme	group	1303:1307	arg1	effect					1274:1279	the freshness preservation effect	1247:1279	the freshness preservation effect of the composite film group	1247:1307	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	3	48	theme	nutritional	681:691	arg1	value					693:697	its high nutritional value	672:697	its high nutritional value	672:697	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	3	49	theme	short	716:720	arg1	life					728:731	a short shelf life	714:731	a short shelf life due to its thin skin and poor storage resistance	714:780	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	5	50	theme	better	1371:1376	arg1	etc.					1428:1431	etc.	1428:1431	etc.	1428:1431	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	50	theme	better	1371:1376	arg1	properties					1392:1401	better antibacterial properties	1371:1401	better antibacterial properties	1371:1401	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	50	theme	better	1371:1376	arg1	properties					1416:1425	antioxidant properties	1404:1425	antioxidant properties	1404:1425	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	4	51	theme	soluble	1066:1072	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	51	theme	soluble	1066:1072	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	5	52	theme	foot	1564:1567	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	2	53	theme	UV	622:623	arg1	light					625:629	UV light	622:629	UV light	622:629	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	54	theme	composite	1584:1592	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	55	theme	control	1351:1357	arg1	group					1359:1363	the control group	1347:1363	the control group	1347:1363	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	1	56	theme	casting	192:198	arg1	method					200:205	solution casting method	183:205	solution casting method using chitosan and golden mushroom foot polysaccharide as substrates	183:274	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	2	57	theme	mechanical	553:562	arg1	properties					564:573	better mechanical properties	546:573	better mechanical properties	546:573	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	0	58	from	application	88:98	arg1	preservation					113:124	blueberry preservation	103:124	blueberry preservation	103:124	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	4	59	used	used	933:936	arg2	group					922:926	the uncovered group	908:926	the uncovered group	908:926	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	59	used	used	933:936	arg2	controls					941:948	controls	941:948	controls	941:948	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	59	used	used	933:936	arg2	group					898:902	the single chitosan film group	873:902	the single chitosan film group	873:902	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	60	theme	single	877:882	arg1	group					922:926	the uncovered group	908:926	the uncovered group	908:926	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	60	theme	single	877:882	arg1	group					898:902	the single chitosan film group	873:902	the single chitosan film group	873:902	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	60	theme	single	877:882	arg1	controls					941:948	controls	941:948	controls	941:948	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	61	theme	anthocyanin	1099:1109	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	5	62	theme	chitosan/Enoki	1540:1553	arg1	film					1607:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	the chitosan/Enoki mushroom foot polysaccharide composite preservation film	1536:1610	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	4	63	used	used	1153:1156	arg2	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	63	used	used	1153:1156	arg2	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	3	64	theme	thin	744:747	arg1	skin					749:752	its thin skin	740:752	its thin skin	740:752	Due to its high nutritional value, blueberry has a short shelf life due to its thin skin and poor storage resistance.					
37379940	4	65	theme	preservation	855:866	arg1	blueberry					809:817	blueberry	809:817	blueberry	809:817	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	65	theme	preservation	855:866	arg1	object					835:840	the object	831:840	the object of freshness preservation	831:866	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	66	theme	electron	436:443	arg1	microscopy					445:454	scanning electron microscopy	427:454	scanning electron microscopy	427:454	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	4	67	theme	uncovered	912:920	arg1	group					922:926	the uncovered group	908:926	the uncovered group	908:926	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	67	theme	uncovered	912:920	arg1	controls					941:948	controls	941:948	controls	941:948	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	67	theme	uncovered	912:920	arg1	group					898:902	the single chitosan film group	873:902	the single chitosan film group	873:902	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	68	dep	structure	285:293	arg1	the					281:283	the	281:283	the	281:283	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	4	69	theme	film	893:896	arg1	group					922:926	the uncovered group	908:926	the uncovered group	908:926	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	69	theme	film	893:896	arg1	group					898:902	the single chitosan film group	873:902	the single chitosan film group	873:902	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	69	theme	film	893:896	arg1	controls					941:948	controls	941:948	controls	941:948	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	70	theme	cling	340:344	arg1	film					346:349	the composite cling film	326:349	the composite cling film	326:349	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	71	theme	cling	156:160	arg1	film					162:165	the composite cling film	142:165	the composite cling film	142:165	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	2	72	theme	single	495:500	arg1	chitosan					502:509	single chitosan film	495:514	single chitosan film	495:514	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	0	73	theme	blueberry	103:111	arg1	preservation					113:124	blueberry preservation	103:124	blueberry preservation	103:124	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	2	74	theme	cling	531:535	arg1	film					537:540	the composite cling film	517:540	the composite cling film	517:540	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	75	contain	has	542:544	arg2	properties					591:600	antioxidant properties	579:600	antioxidant properties	579:600	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	75	contain	has	542:544	arg2	properties					564:573	better mechanical properties	546:573	better mechanical properties	546:573	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	2	75	contain	has	542:544	arg1	film					537:540	the composite cling film	517:540	the composite cling film	517:540	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	76	theme	freshness	1251:1259	arg1	higher					1327:1332	higher	1327:1332	higher	1327:1332	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	76	theme	freshness	1251:1259	arg1	effect					1274:1279	the freshness preservation effect	1247:1279	the freshness preservation effect of the composite film group	1247:1307	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	4	77	theme	VC	1124:1125	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	77	theme	VC	1124:1125	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	78	theme	infrared	381:388	arg1	spectroscopy					390:401	Fourier infrared spectroscopy	373:401	Fourier infrared spectroscopy	373:401	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	2	79	theme	better	546:551	arg1	properties					564:573	better mechanical properties	546:573	better mechanical properties	546:573	The results showed that compared with single chitosan film, the composite cling film has better mechanical properties and antioxidant properties, and the barrier of UV light and water vapor is also stronger.					
37379940	5	80	theme	antioxidant	1404:1414	arg1	properties					1392:1401	better antibacterial properties	1371:1401	better antibacterial properties	1371:1401	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	80	theme	antioxidant	1404:1414	arg1	properties					1416:1425	antioxidant properties	1404:1425	antioxidant properties	1404:1425	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	81	theme	new	1638:1640	arg1	material					1665:1672	a new freshness preservation material	1636:1672	a new freshness preservation material for blueberry	1636:1686	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	0	82	theme	mushroom	30:37	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	0	83	theme	polysaccharide	44:57	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	5	84	theme	high	1618:1621	arg1	potential					1623:1631	a high potential	1616:1631	a high potential as a new freshness preservation material for blueberry	1616:1686	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	0	85	theme	cling	69:73	arg1	film					75:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	chitosan/Enoki mushroom foot polysaccharide composite cling film	15:78	Preparation of chitosan/Enoki mushroom foot polysaccharide composite cling film and its application in blueberry preservation.					
37379940	4	86	theme	preservation	1171:1182	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	86	theme	preservation	1171:1182	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	content					1127:1133	VC content	1124:1133	VC content	1124:1133	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	hardness					1056:1063	hardness	1056:1063	hardness	1056:1063	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	indexes					1184:1190	freshness preservation indexes	1161:1190	freshness preservation indexes for experiments	1161:1206	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	intensity					1020:1028	respiration intensity	1008:1028	respiration intensity	1008:1028	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	content					1111:1117	anthocyanin content	1099:1117	anthocyanin content	1099:1117	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	colony					988:993	total bacterial colony	972:993	total bacterial colony	972:993	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	solids					1074:1079	soluble solids	1066:1079	soluble solids	1066:1079	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	content					1047:1053	malondialdehyde content	1031:1053	malondialdehyde content	1031:1053	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	loss					966:969	the weight loss	955:969	the weight loss	955:969	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	rate					1002:1005	decay rate	996:1005	decay rate	996:1005	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	4	87	theme	decay	996:1000	arg1	acid					1093:1096	titratable acid	1082:1096	titratable acid	1082:1096	Therefore, in this study, blueberry was used as the object of freshness preservation, and the single chitosan film group and the uncovered group were used as controls, and the weight loss, total bacterial colony, decay rate, respiration intensity, malondialdehyde content, hardness, soluble solids, titratable acid, anthocyanin content, and VC content of blueberry were used as freshness preservation indexes for experiments.					
37379940	1	88	theme	golden	226:231	arg1	substrates					265:274	substrates	265:274	substrates	265:274	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	88	theme	golden	226:231	arg1	polysaccharide					247:260	golden mushroom foot polysaccharide	226:260	golden mushroom foot polysaccharide	226:260	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	88	theme	golden	226:231	arg1	chitosan					213:220	chitosan	213:220	chitosan	213:220	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	5	89	theme	film	1298:1301	arg1	group					1303:1307	the composite film group	1284:1307	the composite film group	1284:1307	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	5	90	theme	preservation	1652:1663	arg1	material					1665:1672	a new freshness preservation material	1636:1672	a new freshness preservation material for blueberry	1636:1686	The comprehensive results showed that the freshness preservation effect of the composite film group was significantly higher than that of the control group, with better antibacterial properties, antioxidant properties, etc., which could effectively delay fruit decay and deterioration, thus prolonging the shelf life, and thus the chitosan/Enoki mushroom foot polysaccharide composite preservation film has a high potential as a new freshness preservation material for blueberry.					
37379940	1	91	theme	foot	242:245	arg1	substrates					265:274	substrates	265:274	substrates	265:274	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	91	theme	foot	242:245	arg1	polysaccharide					247:260	golden mushroom foot polysaccharide	226:260	golden mushroom foot polysaccharide	226:260	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37379940	1	91	theme	foot	242:245	arg1	chitosan					213:220	chitosan	213:220	chitosan	213:220	In this study, the composite cling film was prepared by solution casting method using chitosan and golden mushroom foot polysaccharide as substrates, and the structure and physicochemical indexes of the composite cling film were characterized by Fourier infrared spectroscopy, X-ray diffraction, and scanning electron microscopy.					
37236562	0	0	theme	mesenchymal	99:109	arg1	encapsulation					121:133	mesenchymal stem cell encapsulation	99:133	mesenchymal stem cell encapsulation	99:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	7	1	theme	cell-based	1212:1221	arg1	applications					1234:1245	the stem cell-based biomedical applications	1203:1245	the stem cell-based biomedical applications	1203:1245	Therefore, the presented work provides a promising platform for MSCs microencapsulation, which may further improve the stem cell-based biomedical applications.					
37236562	5	2	theme	antioxidant	891:901	arg1	properties					903:912	antioxidant properties	891:912	antioxidant properties	891:912	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	3	3	theme	dopamine-modified	534:550	arg1	HA-Tyr/HA-DA					569:580	HA-Tyr/HA-DA	569:580	HA-Tyr/HA-DA	569:580	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	3	3	theme	dopamine-modified	534:550	arg1	acid					563:566	dopamine-modified hyaluronic acid	534:566	dopamine-modified hyaluronic acid (HA-Tyr/HA-DA)	534:581	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	4	4	theme	cord-derived	625:636	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	4	theme	cord-derived	625:636	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	4	theme	cord-derived	625:636	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	6	5	theme	high	991:994	arg1	viability					996:1004	a high viability	989:1004	a high viability	989:1004	The hUC-MSCs encapsulated in microgels showed a high viability and a significantly improved the survival rate under oxidative stress conditions.					
37236562	5	6	contain	have	849:852	arg1	hydrogel					820:827	The HA-Tyr/HA-DA hydrogel	803:827	The HA-Tyr/HA-DA hydrogel	803:827	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	5	6	contain	have	849:852	arg2	biocompatibility					869:884	biocompatibility	869:884	biocompatibility	869:884	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	5	6	contain	have	849:852	arg2	rheology					859:866	good rheology	854:866	good rheology	854:866	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	5	6	contain	have	849:852	arg2	properties					903:912	antioxidant properties	891:912	antioxidant properties	891:912	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	2	7	theme	shear	368:372	arg1	force					374:378	the shear force	364:378	the shear force during injection and the oxidative stress microenvironments in the lesion area	364:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	4	8	theme	umbilical	615:623	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	8	theme	umbilical	615:623	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	8	theme	umbilical	615:623	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	0	9	theme	cell	116:119	arg1	encapsulation					121:133	mesenchymal stem cell encapsulation	99:133	mesenchymal stem cell encapsulation	99:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	4	10	theme	stem	650:653	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	10	theme	stem	650:653	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	10	theme	stem	650:653	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	0	11	theme	stem	111:114	arg1	encapsulation					121:133	mesenchymal stem cell encapsulation	99:133	mesenchymal stem cell encapsulation	99:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	4	12	theme	size-controllable	753:769	arg1	microgels					791:799	hUC-MSCs@microgels	782:799	hUC-MSCs@microgels	782:799	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	12	theme	size-controllable	753:769	arg1	microgels					771:779	size-controllable microgels	753:779	size-controllable microgels (hUC-MSCs@microgels)	753:800	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	13	theme	mesenchymal	638:648	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	13	theme	mesenchymal	638:648	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	13	theme	mesenchymal	638:648	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	2	14	dep	injection	387:395	arg1	microenvironments					422:438	microenvironments	422:438	microenvironments	422:438	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	6	15	theme	stress	1069:1074	arg1	conditions					1076:1085	oxidative stress conditions	1059:1085	oxidative stress conditions	1059:1085	The hUC-MSCs encapsulated in microgels showed a high viability and a significantly improved the survival rate under oxidative stress conditions.					
37236562	2	16	from	force	374:378	arg1	area					454:457	the lesion area	443:457	the lesion area	443:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	2	17	theme	intravenous	296:306	arg1	injection					308:316	direct intravenous injection	289:316	direct intravenous injection	289:316	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	2	18	theme	oxidative	405:413	arg1	stress					415:420	the oxidative stress	401:420	the oxidative stress	401:420	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	0	19	theme	hyaluronic	20:29	arg1	acid					31:34	Photo-crosslinkable hyaluronic acid	0:34	Photo-crosslinkable hyaluronic acid	0:34	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	2	20	theme	cell	343:346	arg1	survival					348:355	low cell survival	339:355	low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area	339:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	4	21	theme	microfluidic	723:734	arg1	system					736:741	a microfluidic system	721:741	a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels)	721:800	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	0	22	theme	Photo-crosslinkable	0:18	arg1	acid					31:34	Photo-crosslinkable hyaluronic acid	0:34	Photo-crosslinkable hyaluronic acid	0:34	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	6	23	theme	oxidative	1059:1067	arg1	conditions					1076:1085	oxidative stress conditions	1059:1085	oxidative stress conditions	1059:1085	The hUC-MSCs encapsulated in microgels showed a high viability and a significantly improved the survival rate under oxidative stress conditions.					
37236562	2	24	theme	low	339:341	arg1	survival					348:355	low cell survival	339:355	low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area	339:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	1	25	theme	various	202:208	arg1	applications					221:232	various biomedical applications	202:232	various biomedical applications	202:232	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	5	26	theme	good	854:857	arg1	rheology					859:866	good rheology	854:866	good rheology	854:866	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	2	27	theme	lesion	447:452	arg1	area					454:457	the lesion area	443:457	the lesion area	443:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	3	28	theme	antioxidant	490:500	arg1	hydrogel					502:509	a photo-crosslinkable antioxidant hydrogel	468:509	a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA)	468:581	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	4	29	theme	human	609:613	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	29	theme	human	609:613	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	29	theme	human	609:613	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	3	30	theme	hyaluronic	552:561	arg1	HA-Tyr/HA-DA					569:580	HA-Tyr/HA-DA	569:580	HA-Tyr/HA-DA	569:580	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	3	30	theme	hyaluronic	552:561	arg1	acid					563:566	dopamine-modified hyaluronic acid	534:566	dopamine-modified hyaluronic acid (HA-Tyr/HA-DA)	534:581	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	0	31	theme	reactive	51:58	arg1	species					67:73	reactive oxygen species	51:73	reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation	51:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	6	32	theme	survival	1039:1046	arg1	rate					1048:1051	the survival rate	1035:1051	a significantly improved the survival rate	1010:1051	The hUC-MSCs encapsulated in microgels showed a high viability and a significantly improved the survival rate under oxidative stress conditions.					
37236562	4	33	theme	HA-Tyr/HA-DA	693:704	arg1	hydrogel					706:713	HA-Tyr/HA-DA hydrogel	693:713	HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels)	693:800	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	7	34	theme	MSCs	1152:1155	arg1	microencapsulation					1157:1174	MSCs microencapsulation	1152:1174	MSCs microencapsulation	1152:1174	Therefore, the presented work provides a promising platform for MSCs microencapsulation, which may further improve the stem cell-based biomedical applications.					
37236562	2	35	theme	therapeutic	257:267	arg1	approaches					269:278	conventional therapeutic approaches	244:278	conventional therapeutic approaches	244:278	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	2	35	theme	therapeutic	257:267	arg1	injection					308:316	direct intravenous injection	289:316	direct intravenous injection	289:316	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	7	36	theme	presented	1103:1111	arg1	work					1113:1116	the presented work	1099:1116	the presented work	1099:1116	Therefore, the presented work provides a promising platform for MSCs microencapsulation, which may further improve the stem cell-based biomedical applications.					
37236562	3	37	theme	photo-crosslinkable	470:488	arg1	hydrogel					502:509	a photo-crosslinkable antioxidant hydrogel	468:509	a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA)	468:581	Herein, a photo-crosslinkable antioxidant hydrogel based on tyramine- and dopamine-modified hyaluronic acid (HA-Tyr/HA-DA) was developed.					
37236562	0	38	theme	species	67:73	arg1	capacity					86:93	reactive oxygen species scavenging capacity	51:93	reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation	51:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	6	39	theme	improved	1026:1033	arg1	rate					1048:1051	the survival rate	1035:1051	a significantly improved the survival rate	1010:1051	The hUC-MSCs encapsulated in microgels showed a high viability and a significantly improved the survival rate under oxidative stress conditions.					
37236562	7	40	theme	promising	1129:1137	arg1	platform					1139:1146	a promising platform	1127:1146	a promising platform	1127:1146	Therefore, the presented work provides a promising platform for MSCs microencapsulation, which may further improve the stem cell-based biomedical applications.					
37236562	2	41	theme	conventional	244:255	arg1	approaches					269:278	conventional therapeutic approaches	244:278	conventional therapeutic approaches	244:278	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	2	41	theme	conventional	244:255	arg1	injection					308:316	direct intravenous injection	289:316	direct intravenous injection	289:316	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	1	42	theme	Mesenchymal	136:146	arg1	cells					153:157	Mesenchymal stem cells	136:157	Mesenchymal stem cells (MSCs)	136:164	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	1	42	theme	Mesenchymal	136:146	arg1	MSCs					160:163	MSCs	160:163	MSCs	160:163	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	0	43	theme	oxygen	60:65	arg1	species					67:73	reactive oxygen species	51:73	reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation	51:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
37236562	7	44	theme	biomedical	1223:1232	arg1	applications					1234:1245	the stem cell-based biomedical applications	1203:1245	the stem cell-based biomedical applications	1203:1245	Therefore, the presented work provides a promising platform for MSCs microencapsulation, which may further improve the stem cell-based biomedical applications.					
37236562	1	45	theme	stem	148:151	arg1	cells					153:157	Mesenchymal stem cells	136:157	Mesenchymal stem cells (MSCs)	136:164	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	1	45	theme	stem	148:151	arg1	MSCs					160:163	MSCs	160:163	MSCs	160:163	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	2	46	theme	direct	289:294	arg1	injection					308:316	direct intravenous injection	289:316	direct intravenous injection	289:316	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	2	47	theme	due	357:359	arg1	survival					348:355	low cell survival	339:355	low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area	339:457	However, conventional therapeutic approaches, such as direct intravenous injection, are associated with low cell survival due to the shear force during injection and the oxidative stress microenvironments in the lesion area.					
37236562	4	48	link	cord-derived	625:636	arg1	Meanwhile					598:606	Meanwhile	598:606	Meanwhile	598:606	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	48	link	cord-derived	625:636	arg1	hUC-MSCs					662:669	hUC-MSCs	662:669	hUC-MSCs	662:669	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	48	link	cord-derived	625:636	arg1	cells					655:659	human umbilical cord-derived mesenchymal stem cells	609:659	human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)	609:670	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	49	theme	hUC-MSCs	782:789	arg1	microgels					791:799	hUC-MSCs@microgels	782:799	hUC-MSCs@microgels	782:799	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	49	theme	hUC-MSCs	782:789	arg1	microgels					771:779	size-controllable microgels	753:779	size-controllable microgels (hUC-MSCs@microgels)	753:800	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	50	theme	@	790:790	arg1	microgels					791:799	hUC-MSCs@microgels	782:799	hUC-MSCs@microgels	782:799	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	4	50	theme	@	790:790	arg1	microgels					771:779	size-controllable microgels	753:779	size-controllable microgels (hUC-MSCs@microgels)	753:800	Meanwhile, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) were encapsulated in HA-Tyr/HA-DA hydrogel using a microfluidic system to create size-controllable microgels (hUC-MSCs@microgels).					
37236562	5	51	theme	HA-Tyr/HA-DA	807:818	arg1	hydrogel					820:827	The HA-Tyr/HA-DA hydrogel	803:827	The HA-Tyr/HA-DA hydrogel	803:827	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	5	52	theme	cell	918:921	arg1	microencapsulation					923:940	cell microencapsulation	918:940	cell microencapsulation	918:940	The HA-Tyr/HA-DA hydrogel was demonstrated to have good rheology, biocompatibility, and antioxidant properties for cell microencapsulation.					
37236562	1	53	theme	biomedical	210:219	arg1	applications					221:232	various biomedical applications	202:232	various biomedical applications	202:232	Mesenchymal stem cells (MSCs) have gained increasing attention in various biomedical applications.					
37236562	0	54	theme	scavenging	75:84	arg1	capacity					86:93	reactive oxygen species scavenging capacity	51:93	reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation	51:133	Photo-crosslinkable hyaluronic acid microgels with reactive oxygen species scavenging capacity for mesenchymal stem cell encapsulation.					
36801295	7	0	theme	energy/power	1197:1208	arg1	density					1210:1216	high energy/power density	1192:1216	high energy/power density (10.7 Wh kg-1/1329.1 W kg-1)	1192:1245	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	0	theme	energy/power	1197:1208	arg1	kg-1					1241:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	4	1	theme	sodium	660:665	arg1	alginate					667:674	sodium alginate	660:674	sodium alginate	660:674	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	1	2	theme	active	151:156	arg1	material					158:165	the active material	147:165	the active material	147:165	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	8	3	theme	gel	1302:1304	arg1	electrodes					1306:1315	gel electrodes	1302:1315	gel electrodes	1302:1315	This work proposes a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder.					
36801295	2	4	theme	materials	323:331	arg1	construction					297:308	the construction	293:308	the construction of electrode materials without the binder	293:350	Therefore, the construction of electrode materials without the binder has been the research focus.					
36801295	2	4	theme	materials	323:331	arg1	focus					374:378	the research focus	361:378	the research focus	361:378	Therefore, the construction of electrode materials without the binder has been the research focus.					
36801295	4	5	theme	remarkable	854:863	arg1	performance					890:900	a remarkable enhanced electrochemical performance	852:900	a remarkable enhanced electrochemical performance	852:900	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	4	6	theme	electron	807:814	arg1	transfer					816:823	electron transfer	807:823	the electron transfer resistance	803:834	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	3	7	dep	binder	439:444	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	7	dep	binder	439:444	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	6	8	theme	6 M	1131:1133	arg1	electrolyte					1139:1149	a 6 M KOH electrolyte	1129:1149	a 6 M KOH electrolyte	1129:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	5	9	theme	up	957:958	arg1	capacitance					942:952	a specific capacitance	931:952	a specific capacitance of up to 1600.25 F g-1	931:975	The rGSC electrode exhibits a specific capacitance of up to 1600.25 F g-1 when the scan rate is 10 mV s-1.					
36801295	7	10	theme	high	1192:1195	arg1	density					1210:1216	high energy/power density	1192:1216	high energy/power density (10.7 Wh kg-1/1329.1 W kg-1)	1192:1245	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	10	theme	high	1192:1195	arg1	kg-1					1241:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	8	11	theme	energy	1328:1333	arg1	density					1335:1341	higher energy density	1321:1341	higher energy density	1321:1341	This work proposes a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder.					
36801295	3	12	theme	oxide/sodium	464:475	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	12	theme	oxide/sodium	464:475	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	4	13	theme	encapsulates	692:703	arg1	CuCo2S4					705:711	better encapsulates CuCo2S4	685:711	better encapsulates CuCo2S4	685:711	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	7	14	theme	specific	1167:1174	arg1	capacitance					1176:1186	a large specific capacitance	1159:1186	a large specific capacitance	1159:1186	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	3	15	theme	reduced	447:453	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	15	theme	reduced	447:453	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	8	16	theme	promising	1269:1277	arg1	strategy					1279:1286	a promising strategy	1267:1286	a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder	1267:1383	This work proposes a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder.					
36801295	1	17	theme	Binder	90:95	arg1	use					97:99	Binder use	90:99	Binder use	90:99	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	2	18	theme	research	365:372	arg1	construction					297:308	the construction	293:308	the construction of electrode materials without the binder	293:350	Therefore, the construction of electrode materials without the binder has been the research focus.					
36801295	2	18	theme	research	365:372	arg1	focus					374:378	the research focus	361:378	the research focus	361:378	Therefore, the construction of electrode materials without the binder has been the research focus.					
36801295	4	19	theme	transfer	816:823	arg1	resistance					825:834	the electron transfer resistance	803:834	the electron transfer resistance	803:834	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	7	20	contain	has	1155:1157	arg2	density					1210:1216	high energy/power density	1192:1216	high energy/power density (10.7 Wh kg-1/1329.1 W kg-1)	1192:1245	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	20	contain	has	1155:1157	arg2	kg-1					1241:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	20	contain	has	1155:1157	arg2	capacitance					1176:1186	a large specific capacitance	1159:1186	a large specific capacitance	1159:1186	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	20	contain	has	1155:1157	arg1	It					1152:1153	It	1152:1153	It	1152:1153	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	3	21	theme	composite	403:411	arg1	electrode					417:425	a novel ternary composite gel electrode	387:425	a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC)	387:513	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	4	22	theme	high	718:721	arg1	pseudo-capacitance					723:740	high pseudo-capacitance	718:740	high pseudo-capacitance	718:740	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	7	23	theme	large	1161:1165	arg1	capacitance					1176:1186	a large specific capacitance	1159:1186	a large specific capacitance	1159:1186	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	1	24	theme	electrochemical	239:253	arg1	activity					255:262	the electrochemical activity	235:262	the electrochemical activity of the electrode	235:279	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	3	25	theme	convenient	537:546	arg1	method					561:566	a convenient hydrothermal method	535:566	a convenient hydrothermal method	535:566	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	8	26	theme	larger	1347:1352	arg1	capacitance					1354:1364	larger capacitance	1347:1364	larger capacitance without the binder	1347:1383	This work proposes a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder.					
36801295	3	27	theme	novel	389:393	arg1	electrode					417:425	a novel ternary composite gel electrode	387:425	a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC)	387:513	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	6	28	theme	activated	1070:1078	arg1	carbon					1080:1085	activated carbon	1070:1085	activated carbon	1070:1085	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	6	29	theme	KOH	1135:1137	arg1	electrolyte					1139:1149	a 6 M KOH electrolyte	1129:1149	a 6 M KOH electrolyte	1129:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	4	30	theme	rGS	615:617	arg1	structure					602:610	the dual-network structure	585:610	the dual-network structure of rGS	585:617	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	0	31	theme	gel	22:24	arg1	electrodes					26:35	gel electrodes	22:35	gel electrodes	22:35	Sodium alginate-based gel electrodes without binder for high-performance supercapacitors.					
36801295	5	32	theme	specific	933:940	arg1	capacitance					942:952	a specific capacitance	931:952	a specific capacitance of up to 1600.25 F g-1	931:975	The rGSC electrode exhibits a specific capacitance of up to 1600.25 F g-1 when the scan rate is 10 mV s-1.					
36801295	1	33	theme	material	158:165	arg1	volume					137:142	the dead volume	128:142	the dead volume of the active material	128:165	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	1	34	theme	active	188:193	arg1	sites					195:199	the active sites	184:199	the active sites	184:199	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	5	35	theme	rGSC	907:910	arg1	electrode					912:920	The rGSC electrode	903:920	The rGSC electrode	903:920	The rGSC electrode exhibits a specific capacitance of up to 1600.25 F g-1 when the scan rate is 10 mV s-1.					
36801295	3	36	theme	gel	413:415	arg1	electrode					417:425	a novel ternary composite gel electrode	387:425	a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC)	387:513	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	37	theme	ternary	395:401	arg1	electrode					417:425	a novel ternary composite gel electrode	387:425	a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC)	387:513	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	1	38	theme	electrode	271:279	arg1	activity					255:262	the electrochemical activity	235:262	the electrochemical activity of the electrode	235:279	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	1	39	from	decrease	223:230	arg1	activity					255:262	the electrochemical activity	235:262	the electrochemical activity of the electrode	235:279	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	4	40	with	bonding	636:642	arg1	pseudo-capacitance					723:740	high pseudo-capacitance	718:740	high pseudo-capacitance	718:740	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	6	41	from	electrode	1116:1124	arg1	electrolyte					1139:1149	a 6 M KOH electrolyte	1129:1149	a 6 M KOH electrolyte	1129:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	0	42	theme	high-performance	56:71	arg1	supercapacitors					73:87	high-performance supercapacitors	56:87	high-performance supercapacitors	56:87	Sodium alginate-based gel electrodes without binder for high-performance supercapacitors.					
36801295	4	43	theme	electrochemical	874:888	arg1	performance					890:900	a remarkable enhanced electrochemical performance	852:900	a remarkable enhanced electrochemical performance	852:900	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	3	44	theme	hydrothermal	548:559	arg1	method					561:566	a convenient hydrothermal method	535:566	a convenient hydrothermal method	535:566	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	2	45	theme	electrode	313:321	arg1	materials					323:331	electrode materials	313:331	electrode materials	313:331	Therefore, the construction of electrode materials without the binder has been the research focus.					
36801295	4	46	theme	enhanced	865:872	arg1	performance					890:900	a remarkable enhanced electrochemical performance	852:900	a remarkable enhanced electrochemical performance	852:900	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	3	47	theme	alginate/copper	477:491	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	47	theme	alginate/copper	477:491	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	48	theme	graphene	455:462	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	48	theme	graphene	455:462	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	4	49	theme	better	685:690	arg1	CuCo2S4					705:711	better encapsulates CuCo2S4	685:711	better encapsulates CuCo2S4	685:711	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	4	50	dep	rGO	652:654	arg1	only					680:683	only	680:683	only	680:683	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	4	51	theme	transfer	776:783	arg1	path					785:788	the electron transfer path	763:788	the electron transfer path	763:788	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	1	52	theme	dead	132:135	arg1	volume					137:142	the dead volume	128:142	the dead volume of the active material	128:165	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	1	53	from	expansion	115:123	arg1	sites					195:199	the active sites	184:199	the active sites	184:199	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	6	54	theme	asymmetric	1014:1023	arg1	electrode					1116:1124	the positive and negative electrode	1090:1124	the positive and negative electrode in a 6 M KOH electrolyte	1090:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	6	54	theme	asymmetric	1014:1023	arg1	supercapacitor					1025:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	4	55	theme	electron	767:774	arg1	path					785:788	the electron transfer path	763:788	the electron transfer path	763:788	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	1	56	from	decline	173:179	arg1	sites					195:199	the active sites	184:199	the active sites	184:199	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	1	57	theme	volume	137:142	arg1	decline					173:179	a decline	171:179	a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode	171:279	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	1	57	theme	volume	137:142	arg1	expansion					115:123	an expansion	112:123	an expansion of the dead volume of the active material	112:165	Binder use results in an expansion of the dead volume of the active material and a decline in the active sites, which will lead to a decrease in the electrochemical activity of the electrode.					
36801295	8	58	theme	higher	1321:1326	arg1	density					1335:1341	higher energy density	1321:1341	higher energy density	1321:1341	This work proposes a promising strategy for designing gel electrodes for higher energy density and larger capacitance without the binder.					
36801295	6	59	theme	positive	1094:1101	arg1	electrode					1116:1124	the positive and negative electrode	1090:1124	the positive and negative electrode in a 6 M KOH electrolyte	1090:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	6	59	theme	positive	1094:1101	arg1	supercapacitor					1025:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	5	60	dep	rate	991:994	arg1	scan					986:989	scan	986:989	scan	986:989	The rGSC electrode exhibits a specific capacitance of up to 1600.25 F g-1 when the scan rate is 10 mV s-1.					
36801295	3	61	theme	cobalt	493:498	arg1	rGSC					509:512	rGSC	509:512	rGSC	509:512	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	3	61	theme	cobalt	493:498	arg1	sulfide					500:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	reduced graphene oxide/sodium alginate/copper cobalt sulfide	447:506	Here, a novel ternary composite gel electrode without the binder (reduced graphene oxide/sodium alginate/copper cobalt sulfide, rGSC) were designed using a convenient hydrothermal method.					
36801295	4	62	theme	hydrogen	627:634	arg1	bonding					636:642	the hydrogen bonding	623:642	the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance	623:740	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	7	63	theme	10.7 Wh	1219:1225	arg1	density					1210:1216	high energy/power density	1192:1216	high energy/power density (10.7 Wh kg-1/1329.1 W kg-1)	1192:1245	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	63	theme	10.7 Wh	1219:1225	arg1	kg-1					1241:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	6	64	theme	negative	1107:1114	arg1	electrode					1116:1124	the positive and negative electrode	1090:1124	the positive and negative electrode in a 6 M KOH electrolyte	1090:1149	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	6	64	theme	negative	1107:1114	arg1	supercapacitor					1025:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor	1010:1038	The asymmetric supercapacitor was constructed with rGSC and activated carbon as the positive and negative electrode in a 6 M KOH electrolyte.					
36801295	4	65	dep	simplifies	752:761	arg1	Benefiting					569:578	Benefiting	569:578	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance	569:740	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
36801295	7	66	theme	kg-1/1329.1 W	1227:1239	arg1	density					1210:1216	high energy/power density	1192:1216	high energy/power density (10.7 Wh kg-1/1329.1 W kg-1)	1192:1245	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	7	66	theme	kg-1/1329.1 W	1227:1239	arg1	kg-1					1241:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	10.7 Wh kg-1/1329.1 W kg-1	1219:1244	It has a large specific capacitance and high energy/power density (10.7 Wh kg-1/1329.1 W kg-1).					
36801295	4	67	theme	dual-network	589:600	arg1	structure					602:610	the dual-network structure	585:610	the dual-network structure of rGS	585:617	Benefiting from the dual-network structure of rGS via the hydrogen bonding between rGO and sodium alginate not only better encapsulates CuCo2S4 with high pseudo-capacitance, but also simplifies the electron transfer path, and reduces the electron transfer resistance, which leads to a remarkable enhanced electrochemical performance.					
37185886	0	0	theme	composite	93:101	arg1	particles					103:111	soy protein/dextran sulfate composite particles	65:111	soy protein/dextran sulfate composite particles	65:111	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	8	1	theme	potential	1350:1358	arg1	highest					1368:1374	highest	1368:1374	highest	1368:1374	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	1	theme	potential	1350:1358	arg1	value					1341:1345	the absolute value	1328:1345	the absolute value of potential	1328:1358	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	7	2	theme	main	1035:1038	arg1	interactions					994:1005	Electrostatic interactions	980:1005	Electrostatic interactions	980:1005	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	2	theme	main	1035:1038	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds	1011:1024	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	2	theme	main	1035:1038	arg1	forces					1040:1045	the main forces	1031:1045	the main forces between SPI and DS	1031:1064	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	3	3	theme	complex	453:459	arg1	concentration					461:473	the high complex concentration	444:473	the high complex concentration emulsion	444:482	And the SPI/DS composite particles were used to prepare the high complex concentration emulsion.					
37185886	1	4	theme	low	234:236	arg1	conditions					245:254	low acidic conditions	234:254	low acidic conditions	234:254	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	0	5	theme	sulfate	85:91	arg1	particles					103:111	soy protein/dextran sulfate composite particles	65:111	soy protein/dextran sulfate composite particles	65:111	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	5	6	theme	SPI/DS	631:636	arg1	particles					648:656	SPI/DS composite particles	631:656	SPI/DS composite particles	631:656	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	3	7	theme	concentration	461:473	arg1	emulsion					475:482	the high complex concentration emulsion	444:482	the high complex concentration emulsion	444:482	And the SPI/DS composite particles were used to prepare the high complex concentration emulsion.					
37185886	1	8	theme	acidic	238:243	arg1	conditions					245:254	low acidic conditions	234:254	low acidic conditions	234:254	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	5	9	theme	absolute	690:697	arg1	value					699:703	the absolute value	686:703	the absolute value of the potential	686:720	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	10	theme	composite	638:646	arg1	particles					648:656	SPI/DS composite particles	631:656	SPI/DS composite particles	631:656	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	1	11	used	used	160:163	arg2	SPI					146:148	SPI	146:148	SPI	146:148	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	11	used	used	160:163	arg2	isolate					137:143	BACKGROUND Soy protein isolate	114:143	BACKGROUND Soy protein isolate (SPI)	114:149	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	11	used	used	160:163	arg2	emulsifier					171:180	an emulsifier	168:180	an emulsifier	168:180	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	10	12	theme	acidic	1600:1605	arg1	conditions					1607:1616	low acidic conditions	1596:1616	low acidic conditions	1596:1616	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	6	13	theme	DS	813:814	arg1	ratio					816:820	the DS ratio	809:820	the DS ratio	809:820	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
37185886	5	14	theme	particles	648:656	arg1	size					623:626	the particle size	610:626	the particle size of SPI/DS composite particles	610:656	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	14	theme	particles	648:656	arg1	smaller					662:668	smaller	662:668	smaller	662:668	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	15	theme	uncompounded	592:603	arg1	SPI					605:607	uncompounded SPI	592:607	uncompounded SPI	592:607	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	2	16	theme	composite	268:276	arg1	particles					278:286	The stable composite particles	257:286	The stable composite particles of SPI and dextran sulfate (DS)	257:318	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	8	17	theme	concentration	1203:1215	arg1	increase					1183:1190	the increase	1179:1190	the increase of complex concentration	1179:1215	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	18	theme	complex	1195:1201	arg1	concentration					1203:1215	complex concentration	1195:1215	complex concentration	1195:1215	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	7	19	theme	hydrogen	1011:1018	arg1	interactions					994:1005	Electrostatic interactions	980:1005	Electrostatic interactions	980:1005	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	19	theme	hydrogen	1011:1018	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds	1011:1024	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	19	theme	hydrogen	1011:1018	arg1	forces					1040:1045	the main forces	1031:1045	the main forces between SPI and DS	1031:1064	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	2	20	theme	stable	261:266	arg1	particles					278:286	The stable composite particles	257:286	The stable composite particles of SPI and dextran sulfate (DS)	257:318	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	8	21	theme	emulsion	1132:1139	arg1	stability					1141:1149	The emulsion stability	1128:1149	The emulsion stability	1128:1149	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	6	22	theme	untreated	907:915	arg1	protein					917:923	the untreated protein	903:923	the untreated protein	903:923	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
37185886	8	23	theme	%	1246:1246	arg1	concentration					1248:1260	1% concentration	1245:1260	1% concentration	1245:1260	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	6	24	theme	particles	865:873	arg1	solubility					837:846	the solubility	833:846	the solubility of the composite particles	833:873	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
37185886	5	25	theme	particle	614:621	arg1	size					623:626	the particle size	610:626	the particle size of SPI/DS composite particles	610:656	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	25	theme	particle	614:621	arg1	smaller					662:668	smaller	662:668	smaller	662:668	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	26	theme	potential	712:720	arg1	value					699:703	the absolute value	686:703	the absolute value of the potential	686:720	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	2	27	theme	dextran	299:305	arg1	DS					316:317	DS	316:317	DS	316:317	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	2	27	theme	dextran	299:305	arg1	sulfate					307:313	dextran sulfate	299:313	dextran sulfate (DS)	299:318	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	9	28	theme	emulsion	1486:1493	arg1	stability					1469:1477	The stability	1465:1477	The stability of the emulsion against freezing	1465:1510	The stability of the emulsion against freezing was improved.					
37185886	2	29	theme	electrostatic	343:355	arg1	interaction					357:367	the electrostatic interaction	339:367	the electrostatic interaction at the pH was 3.5	339:385	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	4	30	theme	complex	522:528	arg1	emulsion					544:551	high complex concentration emulsion	517:551	high complex concentration emulsion	517:551	The stabilization properties of high complex concentration emulsion were investigated.					
37185886	8	31	theme	absolute	1332:1339	arg1	highest					1368:1374	highest	1368:1374	highest	1368:1374	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	31	theme	absolute	1332:1339	arg1	value					1341:1345	the absolute value	1328:1345	the absolute value of potential	1328:1358	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	0	32	theme	complex	20:26	arg1	emulsion					42:49	high complex concentration emulsion	15:49	high complex concentration emulsion	15:49	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	4	33	theme	high	517:520	arg1	emulsion					544:551	high complex concentration emulsion	517:551	high complex concentration emulsion	517:551	The stabilization properties of high complex concentration emulsion were investigated.					
37185886	2	34	theme	SPI	291:293	arg1	particles					278:286	The stable composite particles	257:286	The stable composite particles of SPI and dextran sulfate (DS)	257:318	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	6	35	theme	surface	946:952	arg1	hydrophobicity					954:967	the surface hydrophobicity	942:967	the surface hydrophobicity	942:967	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
37185886	0	36	theme	high	15:18	arg1	emulsion					42:49	high complex concentration emulsion	15:49	high complex concentration emulsion	15:49	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	4	37	theme	emulsion	544:551	arg1	properties					503:512	The stabilization properties	485:512	The stabilization properties of high complex concentration emulsion	485:551	The stabilization properties of high complex concentration emulsion were investigated.					
37185886	7	38	theme	Electrostatic	980:992	arg1	interactions					994:1005	Electrostatic interactions	980:1005	Electrostatic interactions	980:1005	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	38	theme	Electrostatic	980:992	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds	1011:1024	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	7	38	theme	Electrostatic	980:992	arg1	forces					1040:1045	the main forces	1031:1045	the main forces between SPI and DS	1031:1064	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	1	39	theme	Soy	125:127	arg1	emulsifier					171:180	an emulsifier	168:180	an emulsifier	168:180	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	39	theme	Soy	125:127	arg1	SPI					146:148	SPI	146:148	SPI	146:148	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	39	theme	Soy	125:127	arg1	isolate					137:143	BACKGROUND Soy protein isolate	114:143	BACKGROUND Soy protein isolate (SPI)	114:149	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	0	40	theme	emulsion	42:49	arg1	Preparation					0:10	Preparation	0:10	Preparation of high complex concentration emulsion	0:49	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	4	41	theme	concentration	530:542	arg1	emulsion					544:551	high complex concentration emulsion	517:551	high complex concentration emulsion	517:551	The stabilization properties of high complex concentration emulsion were investigated.					
37185886	10	42	theme	well	1658:1661	arg1	stability					1663:1671	a well stability	1656:1671	a well stability	1656:1671	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	8	43	theme	droplet	1285:1291	arg1	size					1293:1296	the emulsion average droplet size	1264:1296	the emulsion average droplet size	1264:1296	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	43	theme	droplet	1285:1291	arg1	lowest					1306:1311	lowest	1306:1311	lowest	1306:1311	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	1	44	theme	BACKGROUND	114:123	arg1	emulsifier					171:180	an emulsifier	168:180	an emulsifier	168:180	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	44	theme	BACKGROUND	114:123	arg1	SPI					146:148	SPI	146:148	SPI	146:148	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	44	theme	BACKGROUND	114:123	arg1	isolate					137:143	BACKGROUND Soy protein isolate	114:143	BACKGROUND Soy protein isolate (SPI)	114:149	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	3	45	theme	composite	403:411	arg1	particles					413:421	the SPI/DS composite particles	392:421	the SPI/DS composite particles	392:421	And the SPI/DS composite particles were used to prepare the high complex concentration emulsion.					
37185886	0	46	theme	concentration	28:40	arg1	emulsion					42:49	high complex concentration emulsion	15:49	high complex concentration emulsion	15:49	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	4	47	theme	stabilization	489:501	arg1	properties					503:512	The stabilization properties	485:512	The stabilization properties of high complex concentration emulsion	485:551	The stabilization properties of high complex concentration emulsion were investigated.					
37185886	8	48	theme	complex	1436:1442	arg1	concentration					1444:1456	the complex concentration	1432:1456	the complex concentration of 8%	1432:1462	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	5	49	theme	SPI	766:768	arg1	1:1					780:782	1:1	780:782	1:1	780:782	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	49	theme	SPI	766:768	arg1	ratio					757:761	the mass ratio	748:761	the mass ratio of SPI to DS	748:774	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	8	50	theme	higher	1230:1235	arg1	times					1224:1228	38.88 times	1218:1228	38.88 times higher than at 1% concentration	1218:1260	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	10	51	theme	low	1596:1598	arg1	conditions					1607:1616	low acidic conditions	1596:1616	low acidic conditions	1596:1616	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	6	52	theme	composite	855:863	arg1	particles					865:873	the composite particles	851:873	the composite particles	851:873	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
37185886	1	53	theme	protein	129:135	arg1	emulsifier					171:180	an emulsifier	168:180	an emulsifier	168:180	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	53	theme	protein	129:135	arg1	SPI					146:148	SPI	146:148	SPI	146:148	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	1	53	theme	protein	129:135	arg1	isolate					137:143	BACKGROUND Soy protein isolate	114:143	BACKGROUND Soy protein isolate (SPI)	114:149	BACKGROUND Soy protein isolate (SPI) could be used as an emulsifier to stabilize emulsions, while SPI is unstable under low acidic conditions.					
37185886	5	54	theme	mass	752:755	arg1	1:1					780:782	1:1	780:782	1:1	780:782	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	5	54	theme	mass	752:755	arg1	ratio					757:761	the mass ratio	748:761	the mass ratio of SPI to DS	748:774	RESULTS Compared to uncompounded SPI, the particle size of SPI/DS composite particles was smaller at 1.52 μm, and the absolute value of the potential increased to 19.9 mV when the mass ratio of SPI to DS was 1:1 and the pH was 3.5.					
37185886	7	55	theme	SPI	1123:1125	arg1	surface					1112:1118	the surface	1108:1118	the surface of SPI	1108:1125	Electrostatic interactions and hydrogen bonds were the main forces between SPI and DS, and DS was electrostatically adsorbed on the surface of SPI.					
37185886	8	56	theme	mass	1396:1399	arg1	ratio					1401:1405	the mass ratio	1392:1405	the mass ratio of SPI to DS	1392:1418	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	56	theme	mass	1396:1399	arg1	1:1					1424:1426	1:1	1424:1426	1:1	1424:1426	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	10	57	theme	high	1560:1563	arg1	solubility					1565:1574	high solubility	1560:1574	high solubility	1560:1574	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	3	58	theme	high	448:451	arg1	concentration					461:473	the high complex concentration	444:473	the high complex concentration emulsion	444:482	And the SPI/DS composite particles were used to prepare the high complex concentration emulsion.					
37185886	10	59	contain	has	1652:1654	arg2	stability					1663:1671	a well stability	1656:1671	a well stability	1656:1671	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	59	contain	has	1652:1654	arg1	emulsion					1643:1650	the SPI/DS complex' emulsion	1623:1650	the SPI/DS complex' emulsion	1623:1650	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	60	contain	has	1556:1558	arg2	solubility					1565:1574	high solubility	1560:1574	high solubility	1560:1574	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	60	contain	has	1556:1558	arg2	stability					1580:1588	stability	1580:1588	stability	1580:1588	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	60	contain	has	1556:1558	arg1	complex					1548:1554	The SPI/DS complex	1537:1554	The SPI/DS complex	1537:1554	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	8	61	theme	average	1277:1283	arg1	size					1293:1296	the emulsion average droplet size	1264:1296	the emulsion average droplet size	1264:1296	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	61	theme	average	1277:1283	arg1	lowest					1306:1311	lowest	1306:1311	lowest	1306:1311	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	3	62	used	used	428:431	arg2	particles					413:421	the SPI/DS composite particles	392:421	the SPI/DS composite particles	392:421	And the SPI/DS composite particles were used to prepare the high complex concentration emulsion.					
37185886	8	63	dep	enhanced	1165:1172	arg1	times					1224:1228	38.88 times	1218:1228	38.88 times higher than at 1% concentration	1218:1260	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	64	theme	1	1245:1245	arg1	%					1246:1246	%	1246:1246	%	1246:1246	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	2	65	from	pH	376:377	arg1	interaction					357:367	the electrostatic interaction	339:367	the electrostatic interaction at the pH was 3.5	339:385	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	2	66	theme	sulfate	307:313	arg1	particles					278:286	The stable composite particles	257:286	The stable composite particles of SPI and dextran sulfate (DS)	257:318	The stable composite particles of SPI and dextran sulfate (DS) could be formed by the electrostatic interaction at the pH was 3.5.					
37185886	10	67	dep	CONCLUSION	1526:1535	arg1	has					1556:1558	has	1556:1558	has high solubility and stability under low acidic conditions	1556:1616	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	67	dep	CONCLUSION	1526:1535	arg1	has					1652:1654	has	1652:1654	has a well stability	1652:1671	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	0	68	theme	protein/dextran	69:83	arg1	particles					103:111	soy protein/dextran sulfate composite particles	65:111	soy protein/dextran sulfate composite particles	65:111	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	8	69	theme	emulsion	1268:1275	arg1	size					1293:1296	the emulsion average droplet size	1264:1296	the emulsion average droplet size	1264:1296	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	69	theme	emulsion	1268:1275	arg1	lowest					1306:1311	lowest	1306:1311	lowest	1306:1311	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	10	70	theme	complex	1634:1640	arg1	emulsion					1643:1650	the SPI/DS complex' emulsion	1623:1650	the SPI/DS complex' emulsion	1623:1650	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	8	71	theme	%	1462:1462	arg1	concentration					1444:1456	the complex concentration	1432:1456	the complex concentration of 8%	1432:1462	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	71	theme	%	1462:1462	arg1	ratio					1401:1405	the mass ratio	1392:1405	the mass ratio of SPI to DS	1392:1418	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	71	theme	%	1462:1462	arg1	1:1					1424:1426	1:1	1424:1426	1:1	1424:1426	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	72	theme	SPI	1410:1412	arg1	ratio					1401:1405	the mass ratio	1392:1405	the mass ratio of SPI to DS	1392:1418	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	8	72	theme	SPI	1410:1412	arg1	1:1					1424:1426	1:1	1424:1426	1:1	1424:1426	The emulsion stability significantly enhanced with the increase of complex concentration (38.88 times higher than at 1% concentration), the emulsion average droplet size was the lowest (9.64 μm), and the absolute value of potential was the highest (46.67 mV) when the mass ratio of SPI to DS was 1:1 and the complex concentration of 8%.					
37185886	0	73	theme	soy	65:67	arg1	particles					103:111	soy protein/dextran sulfate composite particles	65:111	soy protein/dextran sulfate composite particles	65:111	Preparation of high complex concentration emulsion stabilized by soy protein/dextran sulfate composite particles.					
37185886	10	74	theme	SPI/DS	1627:1632	arg1	emulsion					1643:1650	the SPI/DS complex' emulsion	1623:1650	the SPI/DS complex' emulsion	1623:1650	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	10	75	theme	SPI/DS	1541:1546	arg1	complex					1548:1554	The SPI/DS complex	1537:1554	The SPI/DS complex	1537:1554	CONCLUSION The SPI/DS complex has high solubility and stability under low acidic conditions, and the SPI/DS complex' emulsion has a well stability.					
37185886	6	76	theme	protein	917:923	arg1	times					894:898	14.44 times	888:898	14.44 times of the untreated protein	888:923	With the DS ratio increased, the solubility of the composite particles increased to 14.44 times of the untreated protein at pH 3.5, while the surface hydrophobicity decreased.					
36308756	13	0	from	application	1742:1752	arg1	industry					1795:1802	the food industry	1786:1802	the food industry	1786:1802	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	10	1	theme	highest	1016:1022	arg1	71.43 °C					1049:1056	71.43 °C	1049:1056	71.43 °C	1049:1056	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	1	theme	highest	1016:1022	arg1	temperature					1030:1040	the highest onset temperature	1012:1040	the highest onset temperature (To ) (71.43 °C)	1012:1057	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	12	2	theme	thermal	1625:1631	arg1	stability					1633:1641	strong thermal stability	1618:1641	strong thermal stability	1618:1641	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	3	3	theme	medicinal	191:199	arg1	plant					201:205	medicinal plant	191:205	medicinal plant	191:205	is widely grown in China and Southeast Asia as a grain crop and medicinal plant.					
36308756	11	4	theme	lowest	1348:1353	arg1	content					1387:1393	rapidly digestible starch (RDS) content	1355:1393	rapidly digestible starch (RDS) content (27.07%)	1355:1402	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	4	theme	lowest	1348:1353	arg1	%					1401:1401	27.07%	1396:1401	27.07%	1396:1401	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	5	theme	low	1250:1252	arg1	level					1254:1258	a low level	1248:1258	a low level of in vitro digestibility	1248:1284	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	6	6	theme	variety	588:594	arg1	granules					571:578	Starch granules	564:578	Starch granules of each variety	564:594	Starch granules of each variety were smooth, sharp, small, and had an average diameter of 2 μm.					
36308756	11	7	from	constant	1440:1447	arg1	NEFS					1461:1464	NEFS	1461:1464	NEFS	1461:1464	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	4	8	theme	hybrid	367:372	arg1	seeds					388:392	hybrid Euryale ferox seeds starch (HEFS)	367:406	hybrid Euryale ferox seeds starch (HEFS)	367:406	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	14	9	theme	Chemical	1823:1830	arg1	Industry					1832:1839	Chemical Industry	1823:1839	Chemical Industry	1823:1839	© 2022 Society of Chemical Industry.					
36308756	12	10	theme	order	1607:1611	arg1	stability					1633:1641	strong thermal stability	1618:1641	strong thermal stability	1618:1641	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	10	theme	order	1607:1611	arg1	granules					1562:1569	compact granules	1554:1569	compact granules	1554:1569	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	10	theme	order	1607:1611	arg1	crystallinity					1577:1589	high crystallinity	1572:1589	high crystallinity	1572:1589	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	10	theme	order	1607:1611	arg1	degree					1597:1602	high degree	1592:1602	high degree of order	1592:1611	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	4	11	theme	seeds	346:350	arg1	properties					284:293	thermal properties	276:293	thermal properties	276:293	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	11	theme	seeds	346:350	arg1	structure					237:245	structure	237:245	structure	237:245	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	11	theme	seeds	346:350	arg1	properties					264:273	physicochemical properties	248:273	physicochemical properties	248:273	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	11	theme	seeds	346:350	arg1	composition					212:222	The composition	208:222	The composition	208:222	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	11	theme	seeds	346:350	arg1	digestibility					309:321	in vitro digestibility	300:321	in vitro digestibility	300:321	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	11	theme	seeds	346:350	arg1	morphology					225:234	morphology	225:234	morphology	225:234	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	13	12	theme	ferox	1765:1769	arg1	starch					1776:1781	Euryale ferox seed starch	1757:1781	Euryale ferox seed starch	1757:1781	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	7	13	theme	A-type	685:690	arg1	crystals					692:699	A-type crystals	685:699	A-type crystals	685:699	All three varieties were A-type crystals with crystallinity ranging from 26.42% to 28.17%.					
36308756	2	14	theme	Euryale	105:111	arg1	Salisb					119:124	BACKGROUND Euryale ferox Salisb	94:124	BACKGROUND Euryale ferox Salisb.	94:125	BACKGROUND Euryale ferox Salisb.					
36308756	11	15	dep	content	1387:1393	arg1	the					1344:1346	the	1344:1346	the	1344:1346	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	13	16	theme	starch	1776:1781	arg1	application					1742:1752	the future application	1731:1752	the future application of Euryale ferox seed starch in the food industry	1731:1802	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	13	17	theme	future	1735:1740	arg1	application					1742:1752	the future application	1731:1752	the future application of Euryale ferox seed starch in the food industry	1731:1802	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	5	18	theme	varieties	481:489	arg1	RESULT					467:472	RESULT	467:472	RESULT Of the varieties that were studied, the amylose content of NEFS (23.03%)	467:545	RESULT Of the varieties that were studied, the amylose content of NEFS (23.03%) was the highest.					
36308756	5	18	theme	varieties	481:489	arg1	highest					555:561	highest	555:561	highest	555:561	RESULT Of the varieties that were studied, the amylose content of NEFS (23.03%) was the highest.					
36308756	4	19	theme	ferox	382:386	arg1	seeds					388:392	hybrid Euryale ferox seeds starch (HEFS)	367:406	hybrid Euryale ferox seeds starch (HEFS)	367:406	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	20	dep	seeds	346:350	arg1	NEFS					360:363	starch (NEFS)	352:364	starch (NEFS)	352:364	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	20	dep	seeds	346:350	arg1	starch					439:444	starch	439:444	starch	439:444	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	0	21	theme	ferox	67:71	arg1	Structure					0:8	Structure	0:8	Structure	0:8	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	0	21	theme	ferox	67:71	arg1	properties					30:39	physicochemical properties	14:39	physicochemical properties	14:39	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	9	22	theme	C1	892:893	arg1	region					895:900	C1 region	892:900	C1 region in NEFS (17.74%) and HEFS (17.66%)	892:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	11	23	theme	hydrolysis	1421:1430	arg1	0.0303					1450:1455	0.0303	1450:1455	0.0303	1450:1455	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	23	theme	hydrolysis	1421:1430	arg1	constant					1440:1447	the slowest hydrolysis kinetic constant	1409:1447	the slowest hydrolysis kinetic constant (0.0303) in NEFS	1409:1464	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	12	24	theme	compact	1554:1560	arg1	granules					1562:1569	compact granules	1554:1569	compact granules	1554:1569	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	5	25	theme	amylose	514:520	arg1	content					522:528	the amylose content	510:528	the amylose content of NEFS (23.03%)	510:545	RESULT Of the varieties that were studied, the amylose content of NEFS (23.03%) was the highest.					
36308756	9	26	from	region	895:900	arg1	NEFS					905:908	NEFS	905:908	NEFS (17.74%)	905:917	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	26	from	region	895:900	arg1	%					916:916	17.74%	911:916	17.74%	911:916	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	26	from	region	895:900	arg1	HEFS					923:926	HEFS	923:926	HEFS (17.66%)	923:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	26	from	region	895:900	arg1	%					934:934	17.66%	929:934	17.66%	929:934	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	4	27	theme	thermal	276:282	arg1	properties					284:293	thermal properties	276:293	thermal properties	276:293	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	28	theme	South	413:417	arg1	seeds					433:437	South Euryale ferox seeds	413:437	South Euryale ferox seeds	413:437	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	13	29	theme	thermodynamic	1682:1694	arg1	properties					1696:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	12	30	theme	NEFS	1529:1532	arg1	attributable					1538:1549	attributable	1538:1549	attributable	1538:1549	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	30	theme	NEFS	1529:1532	arg1	digestibility					1512:1524	the low digestibility	1504:1524	the low digestibility of NEFS	1504:1532	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	4	31	theme	ferox	427:431	arg1	seeds					433:437	South Euryale ferox seeds	413:437	South Euryale ferox seeds	413:437	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	10	32	theme	peak	1188:1191	arg1	1514 mPa·s					1204:1213	1514 mPa·s	1204:1213	1514 mPa·s	1204:1213	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	32	theme	peak	1188:1191	arg1	viscosity					1193:1201	peak viscosity	1188:1201	peak viscosity (1514 mPa·s)	1188:1214	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	33	theme	peak	1060:1063	arg1	Tp					1078:1079	Tp	1078:1079	Tp	1078:1079	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	33	theme	peak	1060:1063	arg1	76.60 °C					1084:1091	76.60 °C	1084:1091	76.60 °C	1084:1091	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	33	theme	peak	1060:1063	arg1	temperature					1065:1075	peak temperature	1060:1075	peak temperature (Tp ) (76.60 °C)	1060:1092	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	3	34	theme	grain	176:180	arg1	crop					182:185	a grain crop	174:185	a grain crop	174:185	is widely grown in China and Southeast Asia as a grain crop and medicinal plant.					
36308756	0	35	theme	physicochemical	14:28	arg1	properties					30:39	physicochemical properties	14:39	physicochemical properties	14:39	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	8	36	theme	double	765:770	arg1	helix					772:776	double helix	765:776	double helix	765:776	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	9	37	from	HEFS	923:926	arg1	proportion					878:887	The high proportion	869:887	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%)	869:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	6	38	theme	Starch	564:569	arg1	granules					571:578	Starch granules	564:578	Starch granules of each variety	564:594	Starch granules of each variety were smooth, sharp, small, and had an average diameter of 2 μm.					
36308756	11	39	theme	starch	1374:1379	arg1	content					1387:1393	rapidly digestible starch (RDS) content	1355:1393	rapidly digestible starch (RDS) content (27.07%)	1355:1402	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	39	theme	starch	1374:1379	arg1	%					1401:1401	27.07%	1396:1401	27.07%	1396:1401	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	40	theme	starch	1314:1319	arg1	%					1340:1340	29.57%	1335:1340	29.57%	1335:1340	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	40	theme	starch	1314:1319	arg1	content					1326:1332	the highest resistant starch (RS) content	1292:1332	the highest resistant starch (RS) content (29.57%)	1292:1341	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	0	41	theme	digestible	48:57	arg1	ferox					67:71	low digestible Euryale ferox	44:71	low digestible Euryale ferox	44:71	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	4	42	theme	ferox	340:344	arg1	seeds					346:350	North Euryale ferox seeds	326:350	North Euryale ferox seeds	326:350	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	42	theme	ferox	340:344	arg1	SEFS					447:450	SEFS	447:450	SEFS	447:450	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	11	43	theme	highest	1296:1302	arg1	%					1340:1340	29.57%	1335:1340	29.57%	1335:1340	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	43	theme	highest	1296:1302	arg1	content					1326:1332	the highest resistant starch (RS) content	1292:1332	the highest resistant starch (RS) content (29.57%)	1292:1341	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	44	theme	resistant	1304:1312	arg1	RS					1322:1323	RS	1322:1323	RS	1322:1323	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	44	theme	resistant	1304:1312	arg1	starch					1314:1319	resistant starch	1304:1319	the highest resistant starch (RS) content (29.57%)	1292:1341	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	4	45	theme	in	300:301	arg1	digestibility					309:321	in vitro digestibility	300:321	in vitro digestibility	300:321	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	9	46	from	NEFS	905:908	arg1	proportion					878:887	The high proportion	869:887	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%)	869:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	10	47	theme	Euryale	983:989	arg1	seeds					997:1001	in North Euryale ferox seeds	974:1001	in North Euryale ferox seeds	974:1001	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	48	theme	onset	1024:1028	arg1	71.43 °C					1049:1056	71.43 °C	1049:1056	71.43 °C	1049:1056	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	48	theme	onset	1024:1028	arg1	temperature					1030:1040	the highest onset temperature	1012:1040	the highest onset temperature (To ) (71.43 °C)	1012:1057	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	49	dep	properties	963:972	arg1	included					1003:1010	included	1003:1010	included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s)	1003:1214	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	2	50	theme	ferox	113:117	arg1	Salisb					119:124	BACKGROUND Euryale ferox Salisb	94:124	BACKGROUND Euryale ferox Salisb.	94:125	BACKGROUND Euryale ferox Salisb.					
36308756	11	51	theme	in	1263:1264	arg1	digestibility					1272:1284	in vitro digestibility	1263:1284	in vitro digestibility	1263:1284	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	12	52	theme	strong	1618:1623	arg1	stability					1633:1641	strong thermal stability	1618:1641	strong thermal stability	1618:1641	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	13	53	theme	digestive	1650:1658	arg1	properties					1696:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	4	54	theme	Euryale	374:380	arg1	seeds					388:392	hybrid Euryale ferox seeds starch (HEFS)	367:406	hybrid Euryale ferox seeds starch (HEFS)	367:406	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	55	theme	starch	352:357	arg1	NEFS					360:363	starch (NEFS)	352:364	starch (NEFS)	352:364	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	6	56	theme	2 μm	654:657	arg1	diameter					642:649	an average diameter	631:649	an average diameter of 2 μm	631:657	Starch granules of each variety were smooth, sharp, small, and had an average diameter of 2 μm.					
36308756	10	57	theme	gelatinization	1148:1161	arg1	enthalpy					1136:1143	enthalpy	1136:1143	enthalpy of gelatinization (ΔH) (12.64 J g-1 )	1136:1181	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	temperature					1030:1040	the highest onset temperature	1012:1040	the highest onset temperature (To ) (71.43 °C)	1012:1057	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	76.60 °C					1084:1091	76.60 °C	1084:1091	76.60 °C	1084:1091	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	12.64 J g-1					1169:1179	12.64 J g-1	1169:1179	12.64 J g-1	1169:1179	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	Tc					1119:1120	Tc	1119:1120	Tc	1119:1120	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	1514 mPa·s					1204:1213	1514 mPa·s	1204:1213	1514 mPa·s	1204:1213	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	temperature					1065:1075	peak temperature	1060:1075	peak temperature (Tp ) (76.60 °C)	1060:1092	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	82.77 °C					1125:1132	82.77 °C	1125:1132	82.77 °C	1125:1132	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	Tp					1078:1079	Tp	1078:1079	Tp	1078:1079	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	temperature					1106:1116	conclusion temperature	1095:1116	conclusion temperature (Tc ) (82.77 °C)	1095:1133	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	71.43 °C					1049:1056	71.43 °C	1049:1056	71.43 °C	1049:1056	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	57	theme	gelatinization	1148:1161	arg1	viscosity					1193:1201	peak viscosity	1188:1201	peak viscosity (1514 mPa·s)	1188:1214	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	8	58	theme	short-range	786:796	arg1	order					798:802	the short-range order	782:802	the short-range order	782:802	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	13	59	theme	seed	1771:1774	arg1	starch					1776:1781	Euryale ferox seed starch	1757:1781	Euryale ferox seed starch	1757:1781	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	2	60	theme	BACKGROUND	94:103	arg1	Salisb					119:124	BACKGROUND Euryale ferox Salisb	94:124	BACKGROUND Euryale ferox Salisb.	94:125	BACKGROUND Euryale ferox Salisb.					
36308756	12	61	theme	high	1592:1595	arg1	degree					1597:1602	high degree	1592:1602	high degree of order	1592:1611	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	13	62	theme	food	1790:1793	arg1	industry					1795:1802	the food industry	1786:1802	the food industry	1786:1802	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	4	63	theme	seeds	388:392	arg1	properties					284:293	thermal properties	276:293	thermal properties	276:293	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	63	theme	seeds	388:392	arg1	structure					237:245	structure	237:245	structure	237:245	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	63	theme	seeds	388:392	arg1	properties					264:273	physicochemical properties	248:273	physicochemical properties	248:273	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	63	theme	seeds	388:392	arg1	composition					212:222	The composition	208:222	The composition	208:222	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	63	theme	seeds	388:392	arg1	digestibility					309:321	in vitro digestibility	300:321	in vitro digestibility	300:321	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	63	theme	seeds	388:392	arg1	morphology					225:234	morphology	225:234	morphology	225:234	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	11	64	theme	digestibility	1272:1284	arg1	level					1254:1258	a low level	1248:1258	a low level of in vitro digestibility	1248:1284	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	13	65	theme	physicochemical	1661:1675	arg1	properties					1696:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties	1644:1705	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	9	66	theme	high	873:876	arg1	proportion					878:887	The high proportion	869:887	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%)	869:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	13	67	theme	Euryale	1757:1763	arg1	starch					1776:1781	Euryale ferox seed starch	1757:1781	Euryale ferox seed starch	1757:1781	These digestive, physicochemical, and thermodynamic properties provide information for the future application of Euryale ferox seed starch in the food industry.					
36308756	11	68	from	content	1387:1393	arg1	NEFS					1461:1464	NEFS	1461:1464	NEFS	1461:1464	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	9	69	theme	region	895:900	arg1	proportion					878:887	The high proportion	869:887	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%)	869:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	11	70	theme	kinetic	1432:1438	arg1	0.0303					1450:1455	0.0303	1450:1455	0.0303	1450:1455	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	70	theme	kinetic	1432:1438	arg1	constant					1440:1447	the slowest hydrolysis kinetic constant	1409:1447	the slowest hydrolysis kinetic constant (0.0303) in NEFS	1409:1464	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	12	71	theme	high	1572:1575	arg1	crystallinity					1577:1589	high crystallinity	1572:1589	high crystallinity	1572:1589	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	4	72	theme	Euryale	419:425	arg1	seeds					433:437	South Euryale ferox seeds	413:437	South Euryale ferox seeds	413:437	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	11	73	theme	slowest	1413:1419	arg1	0.0303					1450:1455	0.0303	1450:1455	0.0303	1450:1455	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	73	theme	slowest	1413:1419	arg1	constant					1440:1447	the slowest hydrolysis kinetic constant	1409:1447	the slowest hydrolysis kinetic constant (0.0303) in NEFS	1409:1464	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	5	74	theme	NEFS	533:536	arg1	content					522:528	the amylose content	510:528	the amylose content of NEFS (23.03%)	510:545	RESULT Of the varieties that were studied, the amylose content of NEFS (23.03%) was the highest.					
36308756	4	75	theme	seeds	433:437	arg1	properties					284:293	thermal properties	276:293	thermal properties	276:293	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	75	theme	seeds	433:437	arg1	structure					237:245	structure	237:245	structure	237:245	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	75	theme	seeds	433:437	arg1	properties					264:273	physicochemical properties	248:273	physicochemical properties	248:273	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	75	theme	seeds	433:437	arg1	composition					212:222	The composition	208:222	The composition	208:222	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	75	theme	seeds	433:437	arg1	digestibility					309:321	in vitro digestibility	300:321	in vitro digestibility	300:321	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	75	theme	seeds	433:437	arg1	morphology					225:234	morphology	225:234	morphology	225:234	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	76	dep	in	300:301	arg1	vitro					303:307	vitro	303:307	vitro	303:307	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	9	77	from	proportion	878:887	arg1	NEFS					905:908	NEFS	905:908	NEFS (17.74%)	905:917	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	77	from	proportion	878:887	arg1	%					916:916	17.74%	911:916	17.74%	911:916	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	77	from	proportion	878:887	arg1	HEFS					923:926	HEFS	923:926	HEFS (17.66%)	923:935	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	9	77	from	proportion	878:887	arg1	%					934:934	17.66%	929:934	17.66%	929:934	The high proportion of C1 region in NEFS (17.74%) and HEFS (17.66%) were found.					
36308756	12	78	dep	CONCLUSION	1467:1476	arg1	revealed					1490:1497	revealed	1490:1497	revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability	1490:1641	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	79	theme	low	1508:1510	arg1	attributable					1538:1549	attributable	1538:1549	attributable	1538:1549	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	12	79	theme	low	1508:1510	arg1	digestibility					1512:1524	the low digestibility	1504:1524	the low digestibility of NEFS	1504:1532	CONCLUSION The results revealed that the low digestibility of NEFS was attributable to compact granules, high crystallinity, high degree of order, and strong thermal stability.					
36308756	0	80	dep	Salisb	73:78	arg1	Structure					0:8	Structure	0:8	Structure	0:8	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	0	80	dep	Salisb	73:78	arg1	properties					30:39	physicochemical properties	14:39	physicochemical properties	14:39	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	8	81	dep	1.6006	847:852	arg1	to					844:845	to	844:845	to	844:845	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	8	82	dep	2.5324	826:831	arg1	to					823:824	to	823:824	to	823:824	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	0	83	theme	low	44:46	arg1	ferox					67:71	low digestible Euryale ferox	44:71	low digestible Euryale ferox	44:71	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	7	84	with	crystals	692:699	arg1	crystallinity					706:718	crystallinity	706:718	crystallinity ranging from 26.42% to 28.17%	706:748	All three varieties were A-type crystals with crystallinity ranging from 26.42% to 28.17%.					
36308756	4	85	theme	physicochemical	248:262	arg1	properties					264:273	physicochemical properties	248:273	physicochemical properties	248:273	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	11	86	theme	digestible	1363:1372	arg1	content					1387:1393	rapidly digestible starch (RDS) content	1355:1393	rapidly digestible starch (RDS) content (27.07%)	1355:1402	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	11	86	theme	digestible	1363:1372	arg1	%					1401:1401	27.07%	1396:1401	27.07%	1396:1401	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	4	87	dep	seeds	388:392	arg1	starch					394:399	starch	394:399	hybrid Euryale ferox seeds starch (HEFS)	367:406	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	87	dep	seeds	388:392	arg1	HEFS					402:405	HEFS	402:405	HEFS	402:405	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	6	88	theme	average	634:640	arg1	diameter					642:649	an average diameter	631:649	an average diameter of 2 μm	631:657	Starch granules of each variety were smooth, sharp, small, and had an average diameter of 2 μm.					
36308756	0	89	theme	Euryale	59:65	arg1	ferox					67:71	low digestible Euryale ferox	44:71	low digestible Euryale ferox	44:71	Structure and physicochemical properties of low digestible Euryale ferox Salisb.					
36308756	10	90	theme	Thermodynamic	949:961	arg1	properties					963:972	Thermodynamic properties	949:972	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).	949:1215	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	8	91	theme	helix	772:776	arg1	degree					755:760	The degree	751:760	The degree of double helix and the short-range order	751:802	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	10	92	theme	conclusion	1095:1104	arg1	temperature					1106:1116	conclusion temperature	1095:1116	conclusion temperature (Tc ) (82.77 °C)	1095:1133	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	92	theme	conclusion	1095:1104	arg1	Tc					1119:1120	Tc	1119:1120	Tc	1119:1120	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	10	92	theme	conclusion	1095:1104	arg1	82.77 °C					1125:1132	82.77 °C	1125:1132	82.77 °C	1125:1132	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	4	93	theme	Euryale	332:338	arg1	seeds					346:350	North Euryale ferox seeds	326:350	North Euryale ferox seeds	326:350	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	4	93	theme	Euryale	332:338	arg1	SEFS					447:450	SEFS	447:450	SEFS	447:450	The composition, morphology, structure, physicochemical properties, thermal properties, and in vitro digestibility of North Euryale ferox seeds starch (NEFS), hybrid Euryale ferox seeds starch (HEFS), and South Euryale ferox seeds starch (SEFS) were studied.					
36308756	10	94	theme	ferox	991:995	arg1	seeds					997:1001	in North Euryale ferox seeds	974:1001	in North Euryale ferox seeds	974:1001	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36308756	8	95	theme	order	798:802	arg1	degree					755:760	The degree	751:760	The degree of double helix and the short-range order	751:802	The degree of double helix and the short-range order ranged from 1.9006 to 2.5324 and 1.4294 to 1.6006, respectively.					
36308756	11	96	dep	in	1263:1264	arg1	vitro					1266:1270	vitro	1266:1270	vitro	1266:1270	All three varieties maintained a low level of in vitro digestibility, with the highest resistant starch (RS) content (29.57%), the lowest rapidly digestible starch (RDS) content (27.07%), and the slowest hydrolysis kinetic constant (0.0303) in NEFS.					
36308756	10	97	theme	in North	974:981	arg1	seeds					997:1001	in North Euryale ferox seeds	974:1001	in North Euryale ferox seeds	974:1001	Thermodynamic properties in North Euryale ferox seeds included the highest onset temperature (To ) (71.43 °C), peak temperature (Tp ) (76.60 °C), conclusion temperature (Tc ) (82.77 °C), enthalpy of gelatinization (ΔH) (12.64 J g-1 ), and peak viscosity (1514 mPa·s).					
36563864	0	0	theme	acid	85:88	arg1	pretreatment					90:101	acid pretreatment	85:101	acid pretreatment	85:101	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	5	1	theme	lignin	1067:1072	arg1	contents					1107:1114	lignin and to some extent hemicellulose contents	1067:1114	lignin and to some extent hemicellulose contents	1067:1114	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	2	2	theme	enzyme	624:629	arg1	concentration					631:643	enzyme concentration	624:643	enzyme concentration	624:643	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	5	3	theme	predictors	1047:1056	arg1	analysis					1027:1034	Sensitivity analysis	1015:1034	Sensitivity analysis of the ANN predictors	1015:1056	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	4	4	dep	R2	952:953	arg1	0.997					956:960	0.997	956:960	0.997	956:960	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	4	5	theme	excellent	902:910	arg1	fitness					912:918	excellent fitness	902:918	excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets	902:1000	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	1	6	theme	pretreatment	265:276	arg1	characteristics					248:262	biomass characteristics	240:262	biomass characteristics	240:262	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	1	6	theme	pretreatment	265:276	arg1	conditions					303:312	pretreatment and enzymatic hydrolysis conditions	265:312	pretreatment and enzymatic hydrolysis conditions	265:312	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	4	7	theme	validation	964:973	arg1	sets					997:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	6	8	theme	diverse	1258:1264	arg1	compositions					1274:1285	diverse biomass compositions	1258:1285	diverse biomass compositions	1258:1285	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	4	9	theme	Genetic	856:862	arg1	model					888:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	2	10	from	literature	360:369	arg1	data					350:353	curated experimental data	329:353	curated experimental data from literature	329:369	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	3	11	from	influence	772:780	arg1	generation					844:853	reducing sugar generation	829:853	reducing sugar generation	829:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	4	12	theme	algorithm-optimized	864:882	arg1	model					888:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	4	13	dep	training	942:949	arg1	R2					952:953	R2	952:953	R2: 0.997	952:960	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	5	14	theme	to	1078:1079	arg1	contents					1107:1114	lignin and to some extent hemicellulose contents	1067:1114	lignin and to some extent hemicellulose contents	1067:1114	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	6	15	theme	better	1220:1225	arg1	predictability					1227:1240	better predictability	1220:1240	better predictability in dataset with diverse biomass compositions	1220:1285	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	6	16	theme	simple	1169:1174	arg1	interpretation					1176:1189	simple interpretation	1169:1189	simple interpretation	1169:1189	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	1	17	theme	enzymatic	282:290	arg1	hydrolysis					292:301	enzymatic hydrolysis	282:301	enzymatic hydrolysis	282:301	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	3	18	theme	positive	718:725	arg1	influence					727:735	positive influence	718:735	positive influence of acid and enzyme	718:754	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	19	dep	cellulose	492:500	arg1	i.e.					486:489	i.e.	486:489	i.e.	486:489	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	4	20	dep	R2	1003:1004	arg1	0.967					1007:1011	0.967	1007:1011	0.967	1007:1011	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	1	21	theme	hydrolysis	292:301	arg1	characteristics					248:262	biomass characteristics	240:262	biomass characteristics	240:262	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	1	21	theme	hydrolysis	292:301	arg1	conditions					303:312	pretreatment and enzymatic hydrolysis conditions	265:312	pretreatment and enzymatic hydrolysis conditions	265:312	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	2	22	theme	cellulose-lignin	534:549	arg1	ratio					551:555	cellulose-lignin ratio	534:555	cellulose-lignin ratio	534:555	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	6	23	theme	ANN	1209:1211	arg1	use					1192:1194	use	1192:1194	use of optimized ANN	1192:1211	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	1	24	theme	lignocellulosic	187:201	arg1	LCB					212:214	LCB	212:214	LCB	212:214	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	1	24	theme	lignocellulosic	187:201	arg1	biomass					203:209	lignocellulosic biomass	187:209	lignocellulosic biomass (LCB)	187:215	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	0	25	theme	enzymatic	107:115	arg1	hydrolysis					117:126	enzymatic hydrolysis	107:126	enzymatic hydrolysis of lignocellulosic biomass	107:153	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	5	26	theme	ANN	1043:1045	arg1	predictors					1047:1056	the ANN predictors	1039:1056	the ANN predictors	1039:1056	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	3	27	theme	time	821:824	arg1	influence					772:780	negative influence	763:780	negative influence of treatment severity, temperature and time on reducing sugar generation	763:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	28	theme	neural	430:435	arg1	model					451:455	multivariate regression and artificial neural network (ANN) model	391:455	model	451:455	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	4	29	dep	offered	894:900	arg1	R2					1003:1004	R2	1003:1004	R2: 0.967	1003:1011	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	6	30	contain	have	1164:1167	arg1	models					1153:1158	polynomial models	1142:1158	polynomial models	1142:1158	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	6	30	contain	have	1164:1167	arg2	interpretation					1176:1189	simple interpretation	1169:1189	simple interpretation	1169:1189	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	3	31	dep	R2	682:683	arg1	Adj.					693:696	Adj.	693:696	Adj.	693:696	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	3	31	dep	R2	682:683	arg1	0.891					686:690	0.891	686:690	0.891	686:690	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	32	theme	artificial	419:428	arg1	model					451:455	multivariate regression and artificial neural network (ANN) model	391:455	model	451:455	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	0	33	theme	Multivariate	0:11	arg1	regression					13:22	Multivariate regression	0:22	Multivariate regression	0:22	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	3	34	dep	Adj.	693:696	arg1	0.849					702:706	0.849	702:706	0.849	702:706	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	3	34	dep	Adj.	693:696	arg1	R2					698:699	R2	698:699	Adj. R2: 0.849	693:706	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	35	theme	experimental	337:348	arg1	data					350:353	curated experimental data	329:353	curated experimental data from literature	329:369	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	4	36	theme	ANN	884:886	arg1	model					888:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model	856:892	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	0	37	theme	artificial	28:37	arg1	network					46:52	artificial neural network	28:52	artificial neural network	28:52	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	3	38	theme	enzyme	749:754	arg1	influence					727:735	positive influence	718:735	positive influence of acid and enzyme	718:754	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	0	39	theme	lignocellulosic	131:145	arg1	biomass					147:153	lignocellulosic biomass	131:153	lignocellulosic biomass	131:153	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	2	40	used	used	375:378	arg2	data					350:353	curated experimental data	329:353	curated experimental data from literature	329:369	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	2	41	theme	curated	329:335	arg1	data					350:353	curated experimental data	329:353	curated experimental data from literature	329:369	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	3	42	theme	temperature	805:815	arg1	influence					772:780	negative influence	763:780	negative influence of treatment severity, temperature and time on reducing sugar generation	763:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	4	43	theme	test	992:995	arg1	sets					997:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	4	44	theme	LCB	924:926	arg1	hydrolysis					928:937	LCB hydrolysis	924:937	LCB hydrolysis	924:937	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	6	45	theme	biomass	1266:1272	arg1	compositions					1274:1285	diverse biomass compositions	1258:1285	diverse biomass compositions	1258:1285	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	3	46	theme	acid	740:743	arg1	influence					727:735	positive influence	718:735	positive influence of acid and enzyme	718:754	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	4	47	theme	training	942:949	arg1	sets					997:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	6	48	with	predictability	1227:1240	arg1	compositions					1274:1285	diverse biomass compositions	1258:1285	diverse biomass compositions	1258:1285	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	2	49	theme	ANN	446:448	arg1	model					451:455	multivariate regression and artificial neural network (ANN) model	391:455	model	451:455	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	2	50	theme	network	437:443	arg1	model					451:455	multivariate regression and artificial neural network (ANN) model	391:455	model	451:455	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	3	51	theme	negative	763:770	arg1	influence					772:780	negative influence	763:780	negative influence of treatment severity, temperature and time on reducing sugar generation	763:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	0	52	theme	neural	39:44	arg1	network					46:52	artificial neural network	28:52	artificial neural network	28:52	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	3	53	theme	reduced	656:662	arg1	model					675:679	Selected reduced polynomial model	647:679	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849)	647:707	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	54	theme	acid	558:561	arg1	concentration					563:575	acid concentration	558:575	acid concentration	558:575	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	2	55	theme	pretreatment	597:608	arg1	severity					610:617	pretreatment severity	597:617	pretreatment severity	597:617	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	3	56	theme	polynomial	664:673	arg1	model					675:679	Selected reduced polynomial model	647:679	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849)	647:707	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	5	57	dep	lignin	1067:1072	arg1	extent					1086:1091	some extent	1081:1091	some extent	1081:1091	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	0	58	theme	biomass	147:153	arg1	pretreatment					90:101	acid pretreatment	85:101	acid pretreatment	85:101	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	0	58	theme	biomass	147:153	arg1	hydrolysis					117:126	enzymatic hydrolysis	107:126	enzymatic hydrolysis of lignocellulosic biomass	107:153	Multivariate regression and artificial neural network modelling of sugar yields from acid pretreatment and enzymatic hydrolysis of lignocellulosic biomass.					
36563864	5	59	theme	hemicellulose	1093:1105	arg1	contents					1107:1114	lignin and to some extent hemicellulose contents	1067:1114	lignin and to some extent hemicellulose contents	1067:1114	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	4	60	dep	validation	964:973	arg1	R2					976:977	R2	976:977	R2: 0.984	976:984	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	4	61	dep	R2	976:977	arg1	0.984					980:984	0.984	980:984	0.984	980:984	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	6	62	theme	optimized	1199:1207	arg1	ANN					1209:1211	optimized ANN	1199:1211	optimized ANN	1199:1211	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	5	63	theme	Sensitivity	1015:1025	arg1	analysis					1027:1034	Sensitivity analysis	1015:1034	Sensitivity analysis of the ANN predictors	1015:1056	Sensitivity analysis of the ANN predictors suggests lignin and to some extent hemicellulose contents can be inhibitory.					
36563864	4	64	from	fitness	912:918	arg1	sets					997:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	training (R2: 0.997), validation (R2: 0.984), and test sets	942:1000	Genetic algorithm-optimized ANN model offered excellent fitness for LCB hydrolysis on training (R2: 0.997), validation (R2: 0.984), and test sets (R2: 0.967).					
36563864	3	65	theme	severity	795:802	arg1	influence					772:780	negative influence	763:780	negative influence of treatment severity, temperature and time on reducing sugar generation	763:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	3	66	theme	Selected	647:654	arg1	model					675:679	Selected reduced polynomial model	647:679	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849)	647:707	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	1	67	theme	sugar	165:169	arg1	generation					171:180	sugar generation	165:180	sugar generation	165:180	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	3	68	theme	reducing	829:836	arg1	generation					844:853	reducing sugar generation	829:853	reducing sugar generation	829:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	1	69	theme	biomass	240:246	arg1	characteristics					248:262	biomass characteristics	240:262	biomass characteristics	240:262	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	1	69	theme	biomass	240:246	arg1	conditions					303:312	pretreatment and enzymatic hydrolysis conditions	265:312	pretreatment and enzymatic hydrolysis conditions	265:312	Reducing sugar generation from lignocellulosic biomass (LCB) is closely linked with biomass characteristics, pretreatment and enzymatic hydrolysis conditions.					
36563864	6	70	theme	polynomial	1142:1151	arg1	models					1153:1158	polynomial models	1142:1158	polynomial models	1142:1158	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	3	71	theme	sugar	838:842	arg1	generation					844:853	reducing sugar generation	829:853	reducing sugar generation	829:853	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	3	72	dep	model	675:679	arg1	R2					682:683	R2	682:683	R2	682:683	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36563864	2	73	theme	lignin	518:523	arg1	content					525:531	lignin content	518:531	lignin content	518:531	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	6	74	from	predictability	1227:1240	arg1	dataset					1245:1251	dataset	1245:1251	dataset	1245:1251	Though polynomial models can have simple interpretation, use of optimized ANN offers better predictability in dataset with diverse biomass compositions.					
36563864	2	75	theme	multivariate	391:402	arg1	regression					404:413	multivariate regression and artificial neural network (ANN) model	391:455	regression	404:413	In this study curated experimental data from literature was used to develop multivariate regression and artificial neural network (ANN) model considering nine predictors (i.e., cellulose, hemicellulose, lignin content, cellulose-lignin ratio, acid concentration, temperature, time, pretreatment severity, and enzyme concentration).					
36563864	3	76	theme	treatment	785:793	arg1	severity					795:802	treatment severity	785:802	treatment severity	785:802	Selected reduced polynomial model (R2: 0.891, Adj. R2: 0.849) suggests positive influence of acid and enzyme, while negative influence of treatment severity, temperature and time on reducing sugar generation.					
36944797	4	0	theme	mechanical	527:536	arg1	loading					538:544	mechanical loading	527:544	mechanical loading (compressive and tensile)	527:570	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	5	1	theme	electrical	683:692	arg1	response					694:701	electrical response	683:701	electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking	683:871	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	1	2	theme	building	160:167	arg1	elements					169:176	building elements	160:176	building elements	160:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	8	3	dep	illustrated	1130:1140	arg1	Using					1087:1091	Using	1087:1091	Using FitzHugh-Nagumo model	1087:1113	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	8	4	theme	FitzHugh-Nagumo	1093:1107	arg1	model					1109:1113	FitzHugh-Nagumo model	1093:1113	FitzHugh-Nagumo model	1093:1113	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	7	5	theme	building	1024:1031	arg1	insoles					1004:1010	intelligent sensing insoles	984:1010	intelligent sensing insoles which are a building block towards more generic reactive fungal wearables	984:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	7	5	theme	building	1024:1031	arg1	block					1033:1037	a building block	1022:1037	a building block towards more generic reactive fungal wearables	1022:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	6	6	theme	electrical	899:908	arg1	activity					910:917	electrical activity	899:917	electrical activity with compressive loading	899:942	We have shown changes in electrical activity with compressive loading.					
36944797	5	7	theme	fungal	629:634	arg1	insoles					636:642	fungal insoles	629:642	fungal insoles	629:642	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	2	8	theme	cellulose	310:318	arg1	fibres					320:325	reconstituted cellulose fibres	296:325	reconstituted cellulose fibres	296:325	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	7	9	theme	intelligent	984:994	arg1	insoles					1004:1010	intelligent sensing insoles	984:1010	intelligent sensing insoles which are a building block towards more generic reactive fungal wearables	984:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	7	9	theme	intelligent	984:994	arg1	block					1033:1037	a building block	1022:1037	a building block towards more generic reactive fungal wearables	1022:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	3	10	theme	augmented	394:402	arg1	sensory					419:425	sensory	419:425	sensory	419:425	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	3	10	theme	augmented	394:402	arg1	functionality					404:416	augmented functionality	394:416	augmented functionality (sensory)	394:426	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	8	11	from	activity	1309:1316	arg1	points					1273:1278	pressure points	1264:1278	pressure points from the mycelium electrical activity	1264:1316	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	5	12	theme	bespoke	706:712	arg1	insoles					714:720	bespoke insoles	706:720	bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus	706:796	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	5	13	theme	insoles	636:642	arg1	potential					616:624	the sensing potential	604:624	the sensing potential of fungal insoles	604:642	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	2	14	theme	reconstituted	296:308	arg1	fibres					320:325	reconstituted cellulose fibres	296:325	reconstituted cellulose fibres	296:325	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	3	15	theme	novel	365:369	arg1	propositions					371:382	novel propositions	365:382	novel propositions including augmented functionality (sensory) and aesthetic (personal fashion)	365:459	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	3	15	theme	novel	365:369	arg1	functionality					404:416	augmented functionality	394:416	augmented functionality (sensory)	394:426	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	3	15	theme	novel	365:369	arg1	aesthetic					432:440	aesthetic	432:440	aesthetic (personal fashion)	432:459	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	4	16	theme	sensing	500:506	arg1	capability					508:517	multiple modal sensing capability	485:517	multiple modal sensing capability	485:517	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	6	17	with	activity	910:917	arg1	loading					936:942	compressive loading	924:942	compressive loading	924:942	We have shown changes in electrical activity with compressive loading.					
36944797	6	18	from	changes	888:894	arg1	activity					910:917	electrical activity	899:917	electrical activity with compressive loading	899:942	We have shown changes in electrical activity with compressive loading.					
36944797	5	19	theme	laboratory	657:666	arg1	experiments					668:678	laboratory experiments	657:678	laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking	657:871	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	7	20	theme	insoles	1004:1010	arg1	development					969:979	the development	965:979	the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables	965:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	1	21	theme	promising	80:88	arg1	composites					65:74	Mycelium bound composites	50:74	Mycelium bound composites	50:74	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	21	theme	promising	80:88	arg1	materials					90:98	promising materials	80:98	promising materials for a diverse range of applications including wearables and building elements	80:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	8	22	theme	pressure	1264:1271	arg1	points					1273:1278	pressure points	1264:1278	pressure points from the mycelium electrical activity	1264:1316	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	5	23	from	experiments	668:678	arg1	response					694:701	electrical response	683:701	electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking	683:871	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	8	24	theme	excitation	1146:1155	arg1	wave-fronts					1157:1167	excitation wave-fronts	1146:1167	excitation wave-fronts	1146:1167	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	5	25	theme	sensing	608:614	arg1	potential					616:624	the sensing potential	604:624	the sensing potential of fungal insoles	604:642	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	2	26	theme	natural	331:337	arg1	fibres					339:344	natural fibres	331:344	natural fibres	331:344	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	8	27	theme	electrical	1298:1307	arg1	activity					1309:1316	the mycelium electrical activity	1285:1316	the mycelium electrical activity	1285:1316	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	4	28	theme	moisture	576:583	arg1	content					585:591	moisture content	576:591	moisture content	576:591	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	7	29	theme	sensing	996:1002	arg1	insoles					1004:1010	intelligent sensing insoles	984:1010	intelligent sensing insoles which are a building block towards more generic reactive fungal wearables	984:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	7	29	theme	sensing	996:1002	arg1	block					1033:1037	a building block	1022:1037	a building block towards more generic reactive fungal wearables	1022:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	8	30	theme	mycelium	1289:1296	arg1	activity					1309:1316	the mycelium electrical activity	1285:1316	the mycelium electrical activity	1285:1316	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	6	31	theme	compressive	924:934	arg1	loading					936:942	compressive loading	924:942	compressive loading	924:942	We have shown changes in electrical activity with compressive loading.					
36944797	1	32	theme	diverse	106:112	arg1	range					114:118	a diverse range	104:118	a diverse range of applications including wearables and building elements	104:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	32	theme	diverse	106:112	arg1	wearables					146:154	wearables	146:154	wearables	146:154	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	32	theme	diverse	106:112	arg1	elements					169:176	building elements	160:176	building elements	160:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	5	33	theme	human	833:837	arg1	loading					839:845	human loading	833:845	human loading	833:845	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	8	34	theme	mycelium	1181:1188	arg1	network					1190:1196	a mycelium network	1179:1196	a mycelium network colonising an insole	1179:1217	Using FitzHugh-Nagumo model we numerically illustrated how excitation wave-fronts behave in a mycelium network colonising an insole and shown that it may be possible to discern pressure points from the mycelium electrical activity.					
36944797	2	35	theme	materials	259:267	arg1	capabilities					221:232	the capabilities	217:232	the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres	217:344	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	0	36	theme	pressure	30:37	arg1	detection					39:47	pressure detection	30:47	pressure detection	30:47	Responsive fungal insoles for pressure detection.					
36944797	3	37	theme	personal	443:450	arg1	aesthetic					432:440	aesthetic	432:440	aesthetic (personal fashion)	432:459	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	3	37	theme	personal	443:450	arg1	fashion					452:458	personal fashion	443:458	personal fashion	443:458	Thereby, creating novel propositions including augmented functionality (sensory) and aesthetic (personal fashion).					
36944797	4	38	theme	modal	494:498	arg1	capability					508:517	multiple modal sensing capability	485:517	multiple modal sensing capability	485:517	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	2	39	theme	passive	251:257	arg1	fibres					288:293	synthetic fibres	278:293	synthetic fibres	278:293	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	2	39	theme	passive	251:257	arg1	materials					259:267	traditionally passive materials	237:267	traditionally passive materials	237:267	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	2	39	theme	passive	251:257	arg1	fibres					320:325	reconstituted cellulose fibres	296:325	reconstituted cellulose fibres	296:325	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	2	39	theme	passive	251:257	arg1	fibres					339:344	natural fibres	331:344	natural fibres	331:344	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	5	40	dep	undertook	647:655	arg1	assess					597:602	assess	597:602	To assess the sensing potential of fungal insoles	594:642	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	5	41	theme	insoles	714:720	arg1	response					694:701	electrical response	683:701	electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking	683:871	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	4	42	theme	multiple	485:492	arg1	capability					508:517	multiple modal sensing capability	485:517	multiple modal sensing capability	485:517	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	5	43	theme	oyster	765:770	arg1	fungi					772:776	oyster fungi	765:776	oyster fungi	765:776	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	4	44	dep	loading	538:544	arg1	tensile					563:569	tensile	563:569	tensile	563:569	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	4	44	dep	loading	538:544	arg1	compressive					547:557	compressive	547:557	compressive	547:557	Biomaterials can offer multiple modal sensing capability such as mechanical loading (compressive and tensile) and moisture content.					
36944797	7	45	theme	fungal	1069:1074	arg1	wearables					1076:1084	more generic reactive fungal wearables	1047:1084	more generic reactive fungal wearables	1047:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	2	46	theme	synthetic	278:286	arg1	fibres					288:293	synthetic fibres	278:293	synthetic fibres	278:293	Their functionality surpasses some of the capabilities of traditionally passive materials, such as synthetic fibres, reconstituted cellulose fibres and natural fibres.					
36944797	1	47	theme	applications	123:134	arg1	range					114:118	a diverse range	104:118	a diverse range of applications including wearables and building elements	104:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	47	theme	applications	123:134	arg1	wearables					146:154	wearables	146:154	wearables	146:154	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	47	theme	applications	123:134	arg1	elements					169:176	building elements	160:176	building elements	160:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	5	48	theme	capillary	732:740	arg1	matting					742:748	capillary matting	732:748	capillary matting colonised with oyster fungi	732:776	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	1	49	theme	bound	59:63	arg1	composites					65:74	Mycelium bound composites	50:74	Mycelium bound composites	50:74	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	49	theme	bound	59:63	arg1	materials					90:98	promising materials	80:98	promising materials for a diverse range of applications including wearables and building elements	80:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	7	50	theme	generic	1052:1058	arg1	wearables					1076:1084	more generic reactive fungal wearables	1047:1084	more generic reactive fungal wearables	1047:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	5	51	theme	compressive	801:811	arg1	stress					813:818	compressive stress	801:818	compressive stress which mimics human loading when standing and walking	801:871	To assess the sensing potential of fungal insoles we undertook laboratory experiments on electrical response of bespoke insoles made from capillary matting colonised with oyster fungi Pleurotus ostreatus to compressive stress which mimics human loading when standing and walking.					
36944797	7	52	theme	reactive	1060:1067	arg1	wearables					1076:1084	more generic reactive fungal wearables	1047:1084	more generic reactive fungal wearables	1047:1084	The results advance the development of intelligent sensing insoles which are a building block towards more generic reactive fungal wearables.					
36944797	1	53	theme	Mycelium	50:57	arg1	composites					65:74	Mycelium bound composites	50:74	Mycelium bound composites	50:74	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
36944797	1	53	theme	Mycelium	50:57	arg1	materials					90:98	promising materials	80:98	promising materials for a diverse range of applications including wearables and building elements	80:176	Mycelium bound composites are promising materials for a diverse range of applications including wearables and building elements.					
35500403	5	0	theme	residual	736:743	arg1	form					745:748	residual form	736:748	residual form	736:748	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	6	1	contain	had	902:904	arg2	impact					913:918	little impact	906:918	little impact	906:918	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	6	1	contain	had	902:904	arg1	CSBT					897:900	CSBT	897:900	CSBT	897:900	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	4	2	theme	0.2 g·kg-1	471:480	arg1	CSBT					482:485	0.2 g·kg-1 CSBT	471:485	0.2 g·kg-1 CSBT	471:485	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	5	3	theme	14.23	790:794	arg1	%					785:785	%	785:785	%	785:785	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	5	4	theme	experiment	643:652	arg1	time					654:657	the experiment time	639:657	the experiment time	639:657	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	7	5	from	state	1100:1104	arg1	soil					1109:1112	soil	1109:1112	soil	1109:1112	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	2	6	theme	chromium	255:262	arg1	forms					246:250	various forms	238:250	various forms of chromium	238:262	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	5	7	from	content	725:731	arg1	Cr					763:764	the total Cr	753:764	the total Cr	753:764	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	7	8	theme	residual	1091:1098	arg1	state					1100:1104	residual state	1091:1104	residual state in soil	1091:1112	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	4	9	theme	exchangeable	534:545	arg1	form					573:576	exchangeable, reducible and oxidizable form	534:576	exchangeable, reducible and oxidizable form	534:576	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	3	10	theme	chromium	445:452	arg1	form					437:440	residual form	428:440	residual form of chromium	428:452	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	5	11	theme	form	745:748	arg1	content					725:731	the content	721:731	the content of residual form in the total Cr	721:764	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	3	12	theme	residual	428:435	arg1	form					437:440	residual form	428:440	residual form of chromium	428:452	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	5	13	theme	total	757:761	arg1	Cr					763:764	the total Cr	753:764	the total Cr	753:764	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	7	14	theme	CSBT	1037:1040	arg1	CSBT					1037:1040	CSBT	1037:1040	CSBT	1037:1040	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	14	theme	CSBT	1037:1040	arg1	groups					1027:1032	The amino, carboxyl and hydroxyl groups	994:1032	groups	1027:1032	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	15	theme	chromium	1150:1157	arg1	bioavailability					1131:1145	the bioavailability	1127:1145	the bioavailability of chromium in soil	1127:1165	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	2	16	theme	various	238:244	arg1	forms					246:250	various forms	238:250	various forms of chromium	238:262	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	2	17	from	influence	203:211	arg1	forms					246:250	various forms	238:250	various forms of chromium	238:262	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	0	18	theme	Cr	9:10	arg1	stabilization					16:28	Cr(VI) stabilization	9:28	Cr(VI) stabilization	9:28	Enhanced Cr(VI) stabilization in soil by chitosan/bentonite composites.					
35500403	5	19	theme	passivation	664:674	arg1	effect					676:681	the passivation effect	660:681	the passivation effect	660:681	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	2	20	theme	batch	284:288	arg1	experiment					290:299	batch experiment	284:299	batch experiment	284:299	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	6	21	theme	soil	936:939	arg1	pH					941:942	soil pH	936:942	soil pH	936:942	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	3	22	theme	form	392:395	arg1	content					348:354	the content	344:354	the content of exchangeable form and oxidizable form	344:395	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	6	23	theme	soil	923:926	arg1	pH					928:929	soil pH	923:929	soil pH	923:929	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	7	24	theme	carboxyl	1005:1012	arg1	CSBT					1037:1040	CSBT	1037:1040	CSBT	1037:1040	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	24	theme	carboxyl	1005:1012	arg1	groups					1027:1032	The amino, carboxyl and hydroxyl groups	994:1032	groups	1027:1032	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	5	25	theme	28th	833:836	arg1	day					838:840	the 28th day	829:840	the 28th day	829:840	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	5	26	dep	%	785:785	arg1	to					787:788	to	787:788	to	787:788	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	1	27	theme	chromium	177:184	arg1	immobilization					159:172	the immobilization	155:172	the immobilization of chromium in the soil	155:196	In this study, chitosan/bentonite composites (CSBT) was synthesized and applied to the immobilization of chromium in the soil.					
35500403	7	28	theme	amino	998:1002	arg1	CSBT					1037:1040	CSBT	1037:1040	CSBT	1037:1040	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	28	theme	amino	998:1002	arg1	groups					1027:1032	The amino, carboxyl and hydroxyl groups	994:1032	groups	1027:1032	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	5	29	theme	subsequent	878:887	arg1	period					889:894	the subsequent period	874:894	the subsequent period	874:894	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	6	30	theme	little	906:911	arg1	impact					913:918	little impact	906:918	little impact	906:918	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	3	31	theme	oxidizable	381:390	arg1	form					392:395	oxidizable form	381:395	oxidizable form	381:395	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	3	32	theme	exchangeable	359:370	arg1	form					372:375	exchangeable form	359:375	exchangeable form	359:375	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	4	33	theme	CSBT	482:485	arg1	addition					459:466	The addition	455:466	The addition of 0.2 g·kg-1 CSBT	455:485	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	0	34	dep	stabilization	16:28	arg1	VI					12:13	VI	12:13	VI	12:13	Enhanced Cr(VI) stabilization in soil by chitosan/bentonite composites.					
35500403	7	35	from	bioavailability	1131:1145	arg1	soil					1162:1165	soil	1162:1165	soil	1162:1165	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	1	36	theme	chitosan/bentonite	87:104	arg1	CSBT					118:121	CSBT	118:121	CSBT	118:121	In this study, chitosan/bentonite composites (CSBT) was synthesized and applied to the immobilization of chromium in the soil.					
35500403	1	36	theme	chitosan/bentonite	87:104	arg1	composites					106:115	chitosan/bentonite composites	87:115	chitosan/bentonite composites (CSBT)	87:122	In this study, chitosan/bentonite composites (CSBT) was synthesized and applied to the immobilization of chromium in the soil.					
35500403	3	37	theme	form	372:375	arg1	content					348:354	the content	344:354	the content of exchangeable form and oxidizable form	344:395	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	4	38	theme	best	495:498	arg1	effect					500:505	the best effect	491:505	the best effect	491:505	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	7	39	theme	available	1069:1077	arg1	chromium					1079:1086	available chromium	1069:1086	available chromium	1069:1086	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	6	40	theme	experiment	975:984	arg1	period					986:991	the experiment period	971:991	the experiment period	971:991	CSBT had little impact on soil pH, and soil pH maintained constant during the experiment period.					
35500403	3	41	theme	form	437:440	arg1	content					417:423	the content	413:423	the content of residual form of chromium	413:452	The results showed that CSBT could reduce the content of exchangeable form and oxidizable form, while increase the content of residual form of chromium.					
35500403	4	42	contain	had	487:489	arg1	addition					459:466	The addition	455:466	The addition of 0.2 g·kg-1 CSBT	455:485	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	4	42	contain	had	487:489	arg2	effect					500:505	the best effect	491:505	the best effect	491:505	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	2	43	theme	agents	228:233	arg1	influence					203:211	The influence	199:211	The influence of passivating agents on various forms of chromium	199:262	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	4	44	theme	reducible	548:556	arg1	form					573:576	exchangeable, reducible and oxidizable form	534:576	exchangeable, reducible and oxidizable form	534:576	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	0	45	theme	chitosan/bentonite	41:58	arg1	composites					60:69	chitosan/bentonite composites	41:69	chitosan/bentonite composites	41:69	Enhanced Cr(VI) stabilization in soil by chitosan/bentonite composites.					
35500403	2	46	theme	passivating	216:226	arg1	agents					228:233	passivating agents	216:233	passivating agents	216:233	The influence of passivating agents on various forms of chromium was investigated by batch experiment.					
35500403	1	47	from	immobilization	159:172	arg1	soil					193:196	the soil	189:196	the soil	189:196	In this study, chitosan/bentonite composites (CSBT) was synthesized and applied to the immobilization of chromium in the soil.					
35500403	5	48	theme	0.76	781:784	arg1	%					785:785	%	785:785	%	785:785	During the experiment time, the passivation effect increased rapidly within 14 days, and the content of residual form in the total Cr increased from 0.76% to 14.23%, the equilibrium was reached at the 28th day and was basically maintained in the subsequent period.					
35500403	4	49	theme	form	573:576	arg1	concentration					517:529	the concentration	513:529	the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively	513:629	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
35500403	7	50	theme	chromium	1079:1086	arg1	conversion					1055:1064	the conversion	1051:1064	the conversion of available chromium to residual state in soil	1051:1112	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	51	theme	hydroxyl	1018:1025	arg1	CSBT					1037:1040	CSBT	1037:1040	CSBT	1037:1040	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	7	51	theme	hydroxyl	1018:1025	arg1	groups					1027:1032	The amino, carboxyl and hydroxyl groups	994:1032	groups	1027:1032	The amino, carboxyl and hydroxyl groups of CSBT promoted the conversion of available chromium to residual state in soil, and reduced the bioavailability of chromium in soil.					
35500403	4	52	theme	oxidizable	562:571	arg1	form					573:576	exchangeable, reducible and oxidizable form	534:576	exchangeable, reducible and oxidizable form	534:576	The addition of 0.2 g·kg-1 CSBT had the best effect, with the concentration of exchangeable, reducible and oxidizable form decreased by 46.74%, 8.15%, and 14.46%, respectively.					
36708071	11	0	theme	bacterial	1204:1212	arg1	structure					1228:1236	the bacterial cell membrane structure	1200:1236	the bacterial cell membrane structure	1200:1236	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	11	1	theme	cell	1214:1217	arg1	structure					1228:1236	the bacterial cell membrane structure	1200:1236	the bacterial cell membrane structure	1200:1236	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	15	2	theme	ChNC	1694:1697	arg1	Cu					1699:1700	ChNC@Cu	1694:1700	ChNC@Cu	1694:1700	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	13	3	theme	special	1373:1379	arg1	structure					1390:1398	The special rod-like structure	1369:1398	The special rod-like structure of ChNC	1369:1406	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	11	4	theme	DNA	1255:1257	arg1	bacteria					1259:1266	the DNA bacteria	1251:1266	the DNA bacteria	1251:1266	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	2	5	theme	pesticides	144:153	arg1	application					120:130	The application	116:130	The application of chemical pesticides in control of plant bacterial disease	116:191	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	5	6	theme	@	643:643	arg1	structure					666:674	a nano rod-like structure	650:674	a nano rod-like structure	650:674	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	6	theme	@	643:643	arg1	Cu					644:645	ChNC@Cu	639:645	ChNC@Cu	639:645	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	3	7	link	bio-derived	348:358	arg1	nanocrystals					367:378	bio-derived chitin nanocrystals	348:378	bio-derived chitin nanocrystals	348:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	14	8	theme	tobacco	1504:1510	arg1	infection					1491:1499	bacterial infection	1481:1499	bacterial infection of tobacco	1481:1510	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	6	9	dep	In	716:717	arg1	vitro					719:723	vitro	719:723	vitro	719:723	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	5	10	theme	other	596:600	arg1	methods					619:625	other characterization methods	596:625	other characterization methods	596:625	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	14	11	contain	has	1449:1451	arg2	effect					1471:1476	a good protective effect	1453:1476	a good protective effect	1453:1476	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	14	11	contain	has	1449:1451	arg1	Cu					1446:1447	ChNC@Cu	1441:1447	ChNC@Cu	1441:1447	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	8	12	theme	ChNC	896:899	arg1	Cu					901:902	ChNC@Cu	896:902	ChNC@Cu	896:902	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	11	13	theme	bacterial	1170:1178	arg1	death					1180:1184	bacterial death	1170:1184	bacterial death	1170:1184	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	13	14	theme	rod-like	1381:1388	arg1	structure					1390:1398	The special rod-like structure	1369:1398	The special rod-like structure of ChNC	1369:1406	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	15	15	theme	green	1673:1677	arg1	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	15	theme	green	1673:1677	arg1	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	14	16	theme	bacterial	1481:1489	arg1	infection					1491:1499	bacterial infection	1481:1499	bacterial infection of tobacco	1481:1510	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	3	17	theme	rod-like	303:310	arg1	ChNC					381:384	ChNC	381:384	ChNC	381:384	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	3	17	theme	rod-like	303:310	arg1	structure					312:320	the special rod-like structure	291:320	the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC)	291:385	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	2	18	theme	potential	203:211	arg1	pollution					227:235	potential environmental pollution	203:235	potential environmental pollution	203:235	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	5	19	theme	nano	652:655	arg1	structure					666:674	a nano rod-like structure	650:674	a nano rod-like structure	650:674	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	19	theme	nano	652:655	arg1	Cu					644:645	ChNC@Cu	639:645	ChNC@Cu	639:645	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	14	20	theme	good	1455:1458	arg1	effect					1471:1476	a good protective effect	1453:1476	a good protective effect	1453:1476	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	3	21	theme	aspect	332:337	arg1	ratio					339:343	high aspect ratio	327:343	high aspect ratio of bio-derived chitin nanocrystals	327:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	10	22	theme	copper	1075:1080	arg1	content					1082:1088	the same copper content	1066:1088	the same copper content	1066:1088	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	11	23	theme	ChNC	1135:1138	arg1	Cu					1140:1141	ChNC@Cu	1135:1141	ChNC@Cu	1135:1141	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	14	24	theme	@	1445:1445	arg1	Cu					1446:1447	ChNC@Cu	1441:1447	ChNC@Cu	1441:1447	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	14	25	theme	ChNC	1605:1608	arg1	Cu					1610:1611	ChNC@Cu	1605:1611	ChNC@Cu has	1605:1615	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	3	26	theme	chitin	360:365	arg1	nanocrystals					367:378	bio-derived chitin nanocrystals	348:378	bio-derived chitin nanocrystals	348:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	15	27	theme	high	1706:1709	arg1	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	27	theme	high	1706:1709	arg1	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	0	28	theme	P.	81:82	arg1	pv					93:94	P. syringae pv	81:94	P. syringae pv	81:94	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	8	29	theme	protective	915:924	arg1	effect					926:931	a good protective effect	908:931	a good protective effect	908:931	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	0	30	dep	P.	81:82	arg1	syringae					84:91	syringae	84:91	syringae	84:91	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	11	31	theme	Cu	1140:1141	arg1	mechanism					1122:1130	the antibacterial mechanism	1104:1130	the antibacterial mechanism of ChNC@Cu	1104:1141	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	9	32	theme	tobacco	962:968	arg1	tabaci					952:957	tabaci	952:957	tabaci of tobacco.	952:969	tabaci of tobacco.					
36708071	3	33	theme	rod-like	407:414	arg1	nanoparticle					416:427	a new Cu composite rod-like nanoparticle	388:427	a new Cu composite rod-like nanoparticle	388:427	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	0	34	theme	Chitin	0:5	arg1	nanocrystals					7:18	Chitin nanocrystals	0:18	Chitin nanocrystals	0:18	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	3	35	with	structure	312:320	arg1	ratio					339:343	high aspect ratio	327:343	high aspect ratio of bio-derived chitin nanocrystals	327:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	3	36	theme	@	449:449	arg1	Cu					450:451	ChNC@Cu	445:451	ChNC@Cu	445:451	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	10	37	theme	@	988:988	arg1	Cu					989:990	ChNC@Cu	984:990	ChNC@Cu	984:990	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	3	38	theme	Cu	394:395	arg1	nanoparticle					416:427	a new Cu composite rod-like nanoparticle	388:427	a new Cu composite rod-like nanoparticle	388:427	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	15	39	theme	bacterial	1766:1774	arg1	diseases					1776:1783	agricultural bacterial diseases	1753:1783	agricultural bacterial diseases	1753:1783	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	6	40	theme	P.	783:784	arg1	pv					795:796	P. syringae pv	783:796	P. syringae pv	783:796	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	5	41	with	structure	666:674	arg1	capacity					697:704	a Cu2+ loading capacity	682:704	a Cu2+ loading capacity of 2.63%	682:713	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	4	42	theme	nanoparticle	499:510	arg1	activity					473:480	The antibacterial activity	455:480	The antibacterial activity of the composite nanoparticle	455:510	The antibacterial activity of the composite nanoparticle was systematically studied and its safety was evaluated.					
36708071	13	43	theme	ChNC	1432:1435	arg1	Cu					1437:1438	ChNC@Cu	1432:1438	ChNC@Cu	1432:1438	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	0	44	theme	new	40:42	arg1	nanomaterial					44:55	a new nanomaterial	38:55	a new nanomaterial with high activity with P. syringae pv	38:94	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	10	45	theme	antibacterial	1011:1023	arg1	activity					1025:1032	stronger antibacterial activity	1002:1032	stronger antibacterial activity	1002:1032	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	6	46	theme	Cu	777:778	arg1	rate					764:767	the inhibition rate	749:767	the inhibition rate of ChNC@Cu to P. syringae pv	749:796	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	3	47	dep	fabricated	433:442	arg1	Cu					450:451	ChNC@Cu	445:451	ChNC@Cu	445:451	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	2	48	dep	BACKGROUND	105:114	arg1	cause					197:201	cause	197:201	may cause potential environmental pollution	193:235	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	11	49	from	study	1095:1099	arg1	mechanism					1122:1130	the antibacterial mechanism	1104:1130	the antibacterial mechanism of ChNC@Cu	1104:1141	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	6	50	theme	ChNC	772:775	arg1	Cu					777:778	ChNC@Cu	772:778	ChNC@Cu	772:778	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	0	51	dep	supported	20:28	arg1	nanomaterial					44:55	a new nanomaterial	38:55	a new nanomaterial with high activity with P. syringae pv	38:94	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	11	52	theme	membrane	1219:1226	arg1	structure					1228:1236	the bacterial cell membrane structure	1200:1236	the bacterial cell membrane structure	1200:1236	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	2	53	theme	bacterial	175:183	arg1	disease					185:191	plant bacterial disease	169:191	plant bacterial disease	169:191	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	14	54	theme	great	1528:1532	arg1	activity					1548:1555	a great antibacterial activity	1526:1555	a great antibacterial activity	1526:1555	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	8	55	theme	In	864:865	arg1	experiments					872:882	In vivo experiments	864:882	In vivo experiments	864:882	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	5	56	dep	RESULTS	569:575	arg1	RESULTS					569:575	RESULTS TEM, FTIR, ICP and other characterization methods	569:625	RESULTS TEM, FTIR, ICP and other characterization methods	569:625	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	56	dep	RESULTS	569:575	arg1	FTIR					582:585	FTIR	582:585	FTIR	582:585	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	56	dep	RESULTS	569:575	arg1	TEM					577:579	TEM	577:579	TEM	577:579	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	56	dep	RESULTS	569:575	arg1	methods					619:625	other characterization methods	596:625	other characterization methods	596:625	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	56	dep	RESULTS	569:575	arg1	ICP					588:590	ICP	588:590	ICP	588:590	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	8	57	dep	P.	936:937	arg1	syringae					939:946	syringae	939:946	syringae	939:946	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	10	58	theme	same	1070:1073	arg1	content					1082:1088	the same copper content	1066:1088	the same copper content	1066:1088	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	15	59	theme	application	1721:1731	arg1	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	59	theme	application	1721:1731	arg1	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	5	60	theme	ChNC	639:642	arg1	structure					666:674	a nano rod-like structure	650:674	a nano rod-like structure	650:674	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	60	theme	ChNC	639:642	arg1	Cu					644:645	ChNC@Cu	639:645	ChNC@Cu	639:645	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	6	61	theme	inhibition	753:762	arg1	rate					764:767	the inhibition rate	749:767	the inhibition rate of ChNC@Cu to P. syringae pv	749:796	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	15	62	theme	agricultural	1753:1764	arg1	diseases					1776:1783	agricultural bacterial diseases	1753:1783	agricultural bacterial diseases	1753:1783	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	2	63	theme	chemical	135:142	arg1	pesticides					144:153	chemical pesticides	135:153	chemical pesticides	135:153	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	12	64	theme	ChNC	1273:1276	arg1	Cu					1278:1279	And ChNC@Cu	1269:1279	Cu	1278:1279	And ChNC@Cu is highly safe for plants and can promote seed germination and plant growth.					
36708071	8	65	theme	@	900:900	arg1	Cu					901:902	ChNC@Cu	896:902	ChNC@Cu	896:902	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	6	66	dep	showed	737:742	arg1	rate					764:767	the inhibition rate	749:767	the inhibition rate of ChNC@Cu to P. syringae pv	749:796	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	14	67	theme	low	1560:1562	arg1	concentration					1569:1581	low Cu2+ concentration	1560:1581	low Cu2+ concentration	1560:1581	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	5	68	theme	characterization	602:617	arg1	methods					619:625	other characterization methods	596:625	other characterization methods	596:625	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	13	69	theme	@	1436:1436	arg1	Cu					1437:1438	ChNC@Cu	1432:1438	ChNC@Cu	1432:1438	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	12	70	theme	@	1277:1277	arg1	Cu					1278:1279	And ChNC@Cu	1269:1279	Cu	1278:1279	And ChNC@Cu is highly safe for plants and can promote seed germination and plant growth.					
36708071	11	71	theme	@	1159:1159	arg1	Cu					1160:1161	ChNC@Cu	1155:1161	ChNC@Cu	1155:1161	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	5	72	theme	rod-like	657:664	arg1	structure					666:674	a nano rod-like structure	650:674	a nano rod-like structure	650:674	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	72	theme	rod-like	657:664	arg1	Cu					644:645	ChNC@Cu	639:645	ChNC@Cu	639:645	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	6	73	theme	In	716:717	arg1	experiments					725:735	In vitro experiments	716:735	In vitro experiments	716:735	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	13	74	theme	ChNC	1403:1406	arg1	structure					1390:1398	The special rod-like structure	1369:1398	The special rod-like structure of ChNC	1369:1406	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	2	75	from	application	120:130	arg1	control					158:164	control	158:164	control of plant bacterial disease	158:191	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	3	76	theme	resistance-inducing	259:277	arg1	ability					279:285	the resistance-inducing ability	255:285	the resistance-inducing ability	255:285	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	15	77	theme	novel	1667:1671	arg1	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	77	theme	novel	1667:1671	arg1	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	2	78	theme	environmental	213:225	arg1	pollution					227:235	potential environmental pollution	203:235	potential environmental pollution	203:235	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	14	79	theme	antibacterial	1640:1652	arg1	effect					1654:1659	antibacterial effect	1640:1659	antibacterial effect	1640:1659	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	8	80	dep	In	864:865	arg1	vivo					867:870	vivo	867:870	vivo	867:870	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	14	81	theme	protective	1460:1469	arg1	effect					1471:1476	a good protective effect	1453:1476	a good protective effect	1453:1476	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	3	82	theme	special	295:301	arg1	ChNC					381:384	ChNC	381:384	ChNC	381:384	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	3	82	theme	special	295:301	arg1	structure					312:320	the special rod-like structure	291:320	the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC)	291:385	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	8	83	contain	had	904:906	arg2	effect					926:931	a good protective effect	908:931	a good protective effect	908:931	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	8	83	contain	had	904:906	arg1	Cu					901:902	ChNC@Cu	896:902	ChNC@Cu	896:902	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	0	84	theme	high	62:65	arg1	activity					67:74	high activity	62:74	high activity	62:74	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	5	85	theme	Cu2+	684:687	arg1	capacity					697:704	a Cu2+ loading capacity	682:704	a Cu2+ loading capacity of 2.63%	682:713	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	5	86	theme	%	713:713	arg1	capacity					697:704	a Cu2+ loading capacity	682:704	a Cu2+ loading capacity of 2.63%	682:713	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	8	87	theme	good	910:913	arg1	effect					926:931	a good protective effect	908:931	a good protective effect	908:931	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	14	88	theme	@	1609:1609	arg1	Cu					1610:1611	ChNC@Cu	1605:1611	ChNC@Cu has	1605:1615	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	12	89	theme	plant	1344:1348	arg1	growth					1350:1355	plant growth	1344:1355	plant growth	1344:1355	And ChNC@Cu is highly safe for plants and can promote seed germination and plant growth.					
36708071	3	90	theme	high	327:330	arg1	ratio					339:343	high aspect ratio	327:343	high aspect ratio of bio-derived chitin nanocrystals	327:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	4	91	theme	composite	489:497	arg1	nanoparticle					499:510	the composite nanoparticle	485:510	the composite nanoparticle	485:510	The antibacterial activity of the composite nanoparticle was systematically studied and its safety was evaluated.					
36708071	11	92	theme	@	1139:1139	arg1	Cu					1140:1141	ChNC@Cu	1135:1141	ChNC@Cu	1135:1141	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	14	93	theme	ChNC	1441:1444	arg1	Cu					1446:1447	ChNC@Cu	1441:1447	ChNC@Cu	1441:1447	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	3	94	theme	nanocrystals	367:378	arg1	ratio					339:343	high aspect ratio	327:343	high aspect ratio of bio-derived chitin nanocrystals	327:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	15	95	theme	potential	1711:1719	arg1	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	95	theme	potential	1711:1719	arg1	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	5	96	theme	loading	689:695	arg1	capacity					697:704	a Cu2+ loading capacity	682:704	a Cu2+ loading capacity of 2.63%	682:713	RESULTS TEM, FTIR, ICP and other characterization methods proved that ChNC@Cu is a nano rod-like structure, with a Cu2+ loading capacity of 2.63%.					
36708071	8	97	theme	P.	936:937	arg1	pv					948:949	P. syringae pv	936:949	P. syringae pv	936:949	In vivo experiments showed that ChNC@Cu had a good protective effect on P. syringae pv.					
36708071	3	98	theme	bio-derived	348:358	arg1	nanocrystals					367:378	bio-derived chitin nanocrystals	348:378	bio-derived chitin nanocrystals	348:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	4	99	theme	antibacterial	459:471	arg1	activity					473:480	The antibacterial activity	455:480	The antibacterial activity of the composite nanoparticle	455:510	The antibacterial activity of the composite nanoparticle was systematically studied and its safety was evaluated.					
36708071	11	100	theme	ChNC	1155:1158	arg1	Cu					1160:1161	ChNC@Cu	1155:1161	ChNC@Cu	1155:1161	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	13	101	dep	CONCLUSION	1358:1367	arg1	enrich					1412:1417	enrich	1412:1417	can enrich Cu2+ to form ChNC@Cu	1408:1438	CONCLUSION The special rod-like structure of ChNC can enrich Cu2+ to form ChNC@Cu.					
36708071	15	102	theme	@	1698:1698	arg1	Cu					1699:1700	ChNC@Cu	1694:1700	ChNC@Cu	1694:1700	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	7	103	theme	copper	833:838	arg1	content					840:846	the copper content	829:846	the copper content	829:846	tabaci was more than 95% when the copper content was 41.6 μg/mL.					
36708071	7	103	theme	copper	833:838	arg1	μg/mL					857:861	41.6 μg/mL	852:861	41.6 μg/mL	852:861	tabaci was more than 95% when the copper content was 41.6 μg/mL.					
36708071	2	104	theme	plant	169:173	arg1	disease					185:191	plant bacterial disease	169:191	plant bacterial disease	169:191	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	10	105	theme	ChNC	984:987	arg1	Cu					989:990	ChNC@Cu	984:990	ChNC@Cu	984:990	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	3	106	with	ability	279:285	arg1	ratio					339:343	high aspect ratio	327:343	high aspect ratio of bio-derived chitin nanocrystals	327:378	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	3	107	theme	composite	397:405	arg1	nanoparticle					416:427	a new Cu composite rod-like nanoparticle	388:427	a new Cu composite rod-like nanoparticle	388:427	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	6	108	dep	P.	783:784	arg1	syringae					786:793	syringae	786:793	syringae	786:793	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	15	109	theme	diseases	1776:1783	arg1	control					1742:1748	control	1742:1748	control of agricultural bacterial diseases	1742:1783	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	3	110	theme	ChNC	445:448	arg1	Cu					450:451	ChNC@Cu	445:451	ChNC@Cu	445:451	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	14	111	theme	Cu2+	1564:1567	arg1	concentration					1569:1581	low Cu2+ concentration	1560:1581	low Cu2+ concentration	1560:1581	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	12	112	theme	seed	1323:1326	arg1	germination					1328:1338	seed germination	1323:1338	seed germination	1323:1338	And ChNC@Cu is highly safe for plants and can promote seed germination and plant growth.					
36708071	3	113	theme	new	390:392	arg1	nanoparticle					416:427	a new Cu composite rod-like nanoparticle	388:427	a new Cu composite rod-like nanoparticle	388:427	Herein, based on the resistance-inducing ability and the special rod-like structure with high aspect ratio of bio-derived chitin nanocrystals (ChNC), a new Cu composite rod-like nanoparticle was fabricated (ChNC@Cu).					
36708071	11	114	theme	antibacterial	1108:1120	arg1	mechanism					1122:1130	the antibacterial mechanism	1104:1130	the antibacterial mechanism of ChNC@Cu	1104:1141	The study on the antibacterial mechanism of ChNC@Cu proved that ChNC@Cu caused bacterial death by destroying the bacterial cell membrane structure and damaging the DNA bacteria.					
36708071	10	115	theme	stronger	1002:1009	arg1	activity					1025:1032	stronger antibacterial activity	1002:1032	stronger antibacterial activity	1002:1032	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	6	116	theme	@	776:776	arg1	Cu					777:778	ChNC@Cu	772:778	ChNC@Cu	772:778	In vitro experiments showed that the inhibition rate of ChNC@Cu to P. syringae pv.					
36708071	2	117	theme	disease	185:191	arg1	control					158:164	control	158:164	control of plant bacterial disease	158:191	BACKGROUND The application of chemical pesticides in control of plant bacterial disease may cause potential environmental pollution.					
36708071	0	118	with	nanomaterial	44:55	arg1	activity					67:74	high activity	62:74	high activity	62:74	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	0	118	with	nanomaterial	44:55	arg1	pv					93:94	P. syringae pv	81:94	P. syringae pv	81:94	Chitin nanocrystals supported Copper: a new nanomaterial with high activity with P. syringae pv.					
36708071	14	119	dep	Cu	1610:1611	arg1	has					1613:1615	has	1613:1615	has	1613:1615	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	15	120	contain	has	1702:1704	arg1	Cu					1699:1700	ChNC@Cu	1694:1700	ChNC@Cu	1694:1700	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	120	contain	has	1702:1704	arg2	value					1733:1737	high potential application value	1706:1737	high potential application value	1706:1737	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	15	120	contain	has	1702:1704	arg2	nanofungicide					1679:1691	a novel green nanofungicide	1665:1691	a novel green nanofungicide	1665:1691	As a novel green nanofungicide, ChNC@Cu has high potential application value in control of agricultural bacterial diseases.					
36708071	14	121	theme	antibacterial	1534:1546	arg1	activity					1548:1555	a great antibacterial activity	1526:1555	a great antibacterial activity	1526:1555	ChNC@Cu has a good protective effect on bacterial infection of tobacco, and achieves a great antibacterial activity at low Cu2+ concentration, which indicated that ChNC@Cu has induced resistance and antibacterial effect.					
36708071	10	122	theme	Thiodiazole	1039:1049	arg1	TC					1059:1060	TC	1059:1060	TC	1059:1060	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
36708071	10	122	theme	Thiodiazole	1039:1049	arg1	copper					1051:1056	Thiodiazole copper	1039:1056	Thiodiazole copper (TC)	1039:1061	In addition, ChNC@Cu exhibited stronger antibacterial activity than Thiodiazole copper (TC) at the same copper content.					
35577192	7	0	theme	fiber	1911:1915	arg1	cN·dtex-1					1922:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	8	1	theme	polymer	2172:2178	arg1	materials					2180:2188	other composite polymer materials	2156:2188	other composite polymer materials	2156:2188	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	7	2	theme	common	1896:1901	arg1	cN·dtex-1					1922:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	3	used	used	1322:1325	arg2	%					1186:1186	the grafting ratio ~150.0%	1161:1186	the grafting ratio ~150.0%	1161:1186	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	3	used	used	1322:1325	arg2	%					1248:1248	St-g-PAN ~81.6%	1234:1248	St-g-PAN ~81.6%	1234:1248	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	3	used	used	1322:1325	arg2	%					1268:1268	homo-PAN ~8.6%	1255:1268	homo-PAN ~8.6%	1255:1268	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	3	used	used	1322:1325	arg2	mixture					1205:1211	the reacting mixture	1192:1211	the reacting mixture containing St ~9.8%	1192:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	4	4	theme	electron	875:882	arg1	SEM					896:898	SEM	896:898	SEM	896:898	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	4	theme	electron	875:882	arg1	microscopy					884:893	scanning electron microscopy	866:893	scanning electron microscopy (SEM)	866:899	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	7	5	theme	textiles	2076:2083	arg1	fields					1996:2001	the fields	1992:2001	the fields	1992:2001	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	3	6	theme	air	588:590	arg1	gap					592:594	air gap	588:594	air gap	588:594	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	1	7	theme	soluble	316:322	arg1	starch					324:329	soluble starch	316:329	soluble starch	316:329	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	6	8	theme	grafting	1165:1172	arg1	ratio					1174:1178	the grafting ratio	1161:1178	the grafting ratio ~150.0%	1161:1186	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	9	theme	gauze	2014:2018	arg1	fields					1996:2001	the fields	1992:2001	the fields	1992:2001	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	10	theme	St-g-PAN	1234:1241	arg1	%					1248:1248	St-g-PAN ~81.6%	1234:1248	St-g-PAN ~81.6%	1234:1248	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	0	11	theme	In-situ	0:6	arg1	fiber					57:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	6	12	theme	hot	1463:1465	arg1	drawing					1467:1473	hot drawing	1463:1473	hot drawing	1463:1473	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	3	13	theme	bath	609:612	arg1	effects					577:583	The effects	573:583	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process	573:669	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	7	14	theme	prepared	1855:1862	arg1	better					1884:1889	better	1884:1889	better	1884:1889	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	14	theme	prepared	1855:1862	arg1	fiber					1874:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	15	dep	met	1573:1575	arg1	1 atm					1751:1755	1 atm	1751:1755	1 atm	1751:1755	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	15	dep	met	1573:1575	arg1	%					1789:1789	relative humidity 65%	1769:1789	relative humidity 65%	1769:1789	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	15	dep	met	1573:1575	arg1	22 °C					1758:1762	22 °C	1758:1762	22 °C	1758:1762	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	16	theme	humidity	1778:1785	arg1	%					1789:1789	relative humidity 65%	1769:1789	relative humidity 65%	1769:1789	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	17	theme	6.0 wt	1292:1297	arg1	%					1298:1298	6.0 wt%	1292:1298	6.0 wt% in concentration	1292:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	18	theme	stretching	1446:1455	arg1	%					1460:1460	positive stretching ~48%	1437:1460	positive stretching ~48%	1437:1460	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	19	from	90 °C	1527:1531	arg1	thermal-setting					1508:1522	thermal-setting	1508:1522	thermal-setting	1508:1522	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	20	theme	strength	1609:1616	arg1	cN·dtex-1					1623:1631	breaking strength 3.41 cN·dtex-1	1600:1631	breaking strength 3.41 cN·dtex-1	1600:1631	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	21	theme	~9.8	1227:1230	arg1	%					1231:1231	St ~9.8%	1224:1231	St ~9.8%	1224:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	22	with	fibers	1588:1593	arg1	cN·dtex-1					1623:1631	breaking strength 3.41 cN·dtex-1	1600:1631	breaking strength 3.41 cN·dtex-1	1600:1631	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	23	theme	ratio	1712:1716	arg1	%					1723:1723	moisture recovery ratio 10.53%	1694:1723	moisture recovery ratio 10.53%	1694:1723	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	23	theme	ratio	1712:1716	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	5	24	theme	sonic	1022:1026	arg1	instrument					1040:1049	Single fiber strength tester and sonic orientation instrument	989:1049	instrument	1040:1049	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	3	25	theme	hot	615:617	arg1	drawing					619:625	drawing	619:625	drawing	619:625	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	6	26	from	80 °C	1501:1505	arg1	drawing					1467:1473	hot drawing	1463:1473	hot drawing	1463:1473	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	26	from	80 °C	1501:1505	arg1	%					1410:1410	coagulation bath concentration ~70%	1376:1410	coagulation bath concentration ~70%	1376:1410	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	26	from	80 °C	1501:1505	arg1	~35 mm					1368:1373	air gap ~35 mm	1360:1373	air gap ~35 mm	1360:1373	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	26	from	80 °C	1501:1505	arg1	%					1460:1460	positive stretching ~48%	1437:1460	positive stretching ~48%	1437:1460	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	26	from	80 °C	1501:1505	arg1	times					1492:1496	stretching 6 times	1479:1496	stretching 6 times at 80 °C	1479:1505	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	26	from	80 °C	1501:1505	arg1	~25 °C					1425:1430	temperature ~25 °C	1413:1430	temperature ~25 °C	1413:1430	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	27	theme	composite	1578:1586	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	27	theme	composite	1578:1586	arg1	fibers					1588:1593	composite fibers	1578:1593	composite fibers with breaking strength 3.41 cN·dtex-1	1578:1631	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	28	theme	reacting	1196:1203	arg1	mixture					1205:1211	the reacting mixture	1192:1211	the reacting mixture containing St ~9.8%	1192:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	29	from	mixture	1205:1211	arg1	solution					1278:1285	DMSO solution	1273:1285	DMSO solution with 6.0 wt% in concentration	1273:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	3	30	theme	thermal-setting	647:661	arg1	process					663:669	thermal-setting process	647:669	thermal-setting process	647:669	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	1	31	theme	polyacrylonitrile	148:164	arg1	solution					191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution	106:198	solution	191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	6	32	theme	shrinkage	1811:1819	arg1	%					1831:1831	boiling water shrinkage ratio 9.60%	1797:1831	boiling water shrinkage ratio 9.60%	1797:1831	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	0	33	theme	spinning	86:93	arg1	technique					95:103	dry-wet spinning technique	78:103	dry-wet spinning technique	78:103	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	5	34	theme	orientation	1113:1123	arg1	degrees					1125:1131	orientation degrees	1113:1131	orientation degrees	1113:1131	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	1	35	theme	PAN	167:169	arg1	solution					191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution	106:198	solution	191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	2	36	used	used	418:421	arg2	DMSO					408:411	DMSO	408:411	DMSO	408:411	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	2	36	used	used	418:421	arg2	sulfoxide					397:405	dimethyl sulfoxide	388:405	dimethyl sulfoxide (DMSO)	388:412	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	2	36	used	used	418:421	arg2	solvent					430:436	the solvent	426:436	the solvent	426:436	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	6	37	theme	boiling	1797:1803	arg1	%					1831:1831	boiling water shrinkage ratio 9.60%	1797:1831	boiling water shrinkage ratio 9.60%	1797:1831	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	38	from	%	1186:1186	arg1	solution					1278:1285	DMSO solution	1273:1285	DMSO solution with 6.0 wt% in concentration	1273:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	1	39	theme	composite	172:180	arg1	solution					191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution	106:198	solution	191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	5	40	theme	fiber	1081:1085	arg1	properties					1098:1107	the fiber mechanical properties	1077:1107	the fiber mechanical properties	1077:1107	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	6	41	theme	length	1556:1561	arg1	mode					1563:1566	constant length mode	1547:1566	constant length mode	1547:1566	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	42	theme	ratio	1821:1825	arg1	%					1831:1831	boiling water shrinkage ratio 9.60%	1797:1831	boiling water shrinkage ratio 9.60%	1797:1831	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	2	43	theme	spinning	553:560	arg1	technique					562:570	dry-wet spinning technique	545:570	dry-wet spinning technique	545:570	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	6	44	theme	breaking	1634:1641	arg1	%					1659:1659	breaking elongation 14.41%	1634:1659	breaking elongation 14.41%	1634:1659	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	44	theme	breaking	1634:1641	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	1	45	dep	St	140:141	arg1	in-situ					109:115	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution	106:198	in-situ	109:115	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	2	46	theme	composite	511:519	arg1	fibers					521:526	St/St-g-PAN/PAN composite fibers	495:526	St/St-g-PAN/PAN composite fibers	495:526	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	1	47	dep	nitrate	357:363	arg1	CAN					366:368	CAN	366:368	CAN	366:368	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	4	48	theme	magnetic	764:771	arg1	resonance					773:781	nuclear magnetic resonance	756:781	solid state nuclear magnetic resonance (13C NMR)	744:791	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	48	theme	magnetic	764:771	arg1	NMR					788:790	13C NMR	784:790	13C NMR	784:790	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	49	theme	coagulation	1376:1386	arg1	%					1410:1410	coagulation bath concentration ~70%	1376:1410	coagulation bath concentration ~70%	1376:1410	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	2	50	theme	spinning	460:467	arg1	solution					469:476	St/St-g-PAN/PAN/DMSO spinning solution	439:476	St/St-g-PAN/PAN/DMSO spinning solution	439:476	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	6	51	contain	containing	1213:1222	arg2	%					1231:1231	St ~9.8%	1224:1231	St ~9.8%	1224:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	51	contain	containing	1213:1222	arg1	mixture					1205:1211	the reacting mixture	1192:1211	the reacting mixture containing St ~9.8%	1192:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	0	52	theme	starch/polyacylonitrile	23:45	arg1	fiber					57:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	6	53	from	%	1298:1298	arg1	concentration					1303:1315	concentration	1303:1315	concentration	1303:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	54	theme	~3.24	1949:1953	arg1	cN·dtex-1					1955:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	4	55	theme	fibers	981:986	arg1	morphology					945:954	morphology	945:954	morphology	945:954	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	55	theme	fibers	981:986	arg1	structure					931:939	the structure	927:939	the structure	927:939	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	56	theme	moisture	1694:1701	arg1	%					1723:1723	moisture recovery ratio 10.53%	1694:1723	moisture recovery ratio 10.53%	1694:1723	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	56	theme	moisture	1694:1701	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	57	theme	air	1360:1362	arg1	~35 mm					1368:1373	air gap ~35 mm	1360:1373	air gap ~35 mm	1360:1373	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	1	58	theme	cerium	350:355	arg1	nitrate					357:363	ammonium cerium nitrate	341:363	ammonium cerium nitrate (CAN)	341:369	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	5	59	theme	strength	1002:1009	arg1	tester					1011:1016	Single fiber strength tester and sonic orientation instrument	989:1049	tester	1011:1016	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	6	60	from	%	1268:1268	arg1	solution					1278:1285	DMSO solution	1273:1285	DMSO solution with 6.0 wt% in concentration	1273:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	drawing					1467:1473	hot drawing	1463:1473	hot drawing	1463:1473	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	%					1410:1410	coagulation bath concentration ~70%	1376:1410	coagulation bath concentration ~70%	1376:1410	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	~35 mm					1368:1373	air gap ~35 mm	1360:1373	air gap ~35 mm	1360:1373	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	parameters					1341:1350	the spinning parameters	1328:1350	the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode	1328:1566	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	%					1460:1460	positive stretching ~48%	1437:1460	positive stretching ~48%	1437:1460	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	times					1492:1496	stretching 6 times	1479:1496	stretching 6 times at 80 °C	1479:1505	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	61	theme	spinning	1332:1339	arg1	~25 °C					1425:1430	temperature ~25 °C	1413:1430	temperature ~25 °C	1413:1430	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	4	62	theme	diffraction	834:844	arg1	XRD					856:858	XRD	856:858	XRD	856:858	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	62	theme	diffraction	834:844	arg1	analysis					846:853	X-ray diffraction analysis	828:853	X-ray diffraction analysis (XRD)	828:859	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	7	63	theme	cotton	1936:1941	arg1	cN·dtex-1					1955:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	64	theme	orientation	1668:1678	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	64	theme	orientation	1668:1678	arg1	factor					1680:1685	sonic orientation factor 0.625	1662:1691	sonic orientation factor 0.625	1662:1691	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	65	theme	protective	2030:2039	arg1	clothing					2041:2048	protective clothing	2030:2048	protective clothing	2030:2048	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	65	theme	protective	2030:2039	arg1	gauze					2014:2018	medical gauze	2006:2018	medical gauze	2006:2018	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	8	66	theme	composite	2162:2170	arg1	materials					2180:2188	other composite polymer materials	2156:2188	other composite polymer materials	2156:2188	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	4	67	dep	Fourier	695:701	arg1	transform					703:711	transform	703:711	transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM)	703:899	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	68	theme	infrared	713:720	arg1	FT-IR					736:740	FT-IR	736:740	FT-IR	736:740	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	68	theme	infrared	713:720	arg1	spectroscopy					722:733	infrared spectroscopy	713:733	infrared spectroscopy (FT-IR)	713:741	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	69	theme	temperature	1413:1423	arg1	~25 °C					1425:1430	temperature ~25 °C	1413:1430	temperature ~25 °C	1413:1430	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	8	70	theme	materials	2180:2188	arg1	preparation					2141:2151	preparation	2141:2151	preparation of other composite polymer materials	2141:2188	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	5	71	theme	Single	989:994	arg1	tester					1011:1016	Single fiber strength tester and sonic orientation instrument	989:1049	tester	1011:1016	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	6	72	theme	homo-PAN	1255:1262	arg1	%					1268:1268	homo-PAN ~8.6%	1255:1268	homo-PAN ~8.6%	1255:1268	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	2	73	theme	dimethyl	388:395	arg1	solvent					430:436	the solvent	426:436	the solvent	426:436	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	2	73	theme	dimethyl	388:395	arg1	DMSO					408:411	DMSO	408:411	DMSO	408:411	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	2	73	theme	dimethyl	388:395	arg1	sulfoxide					397:405	dimethyl sulfoxide	388:405	dimethyl sulfoxide (DMSO)	388:412	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	1	74	theme	copolymerizing	282:295	arg1	acrylonitrile					297:309	graft copolymerizing acrylonitrile	276:309	graft copolymerizing acrylonitrile from soluble starch	276:329	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	6	75	theme	standard	1731:1738	arg1	condition					1740:1748	standard condition	1731:1748	standard condition	1731:1748	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	76	theme	concentration	1393:1405	arg1	%					1410:1410	coagulation bath concentration ~70%	1376:1410	coagulation bath concentration ~70%	1376:1410	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	77	theme	viscose	1903:1909	arg1	cN·dtex-1					1922:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	common viscose fiber 2.11 cN·dtex-1	1896:1930	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	4	78	theme	scanning	866:873	arg1	SEM					896:898	SEM	896:898	SEM	896:898	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	78	theme	scanning	866:873	arg1	microscopy					884:893	scanning electron microscopy	866:893	scanning electron microscopy (SEM)	866:899	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	79	theme	ratio	1174:1178	arg1	%					1186:1186	the grafting ratio ~150.0%	1161:1186	the grafting ratio ~150.0%	1161:1186	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	80	with	solution	1278:1285	arg1	%					1298:1298	6.0 wt%	1292:1298	6.0 wt% in concentration	1292:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	1	81	theme	spinning	182:189	arg1	solution					191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution	106:198	solution	191:198	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	1	82	from	starch	324:329	arg1	acrylonitrile					297:309	graft copolymerizing acrylonitrile	276:309	graft copolymerizing acrylonitrile from soluble starch	276:329	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	3	83	theme	coagulation	597:607	arg1	bath					609:612	coagulation bath	597:612	coagulation bath	597:612	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	7	84	used	used	1984:1987	arg2	better					1884:1889	better	1884:1889	better	1884:1889	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	84	used	used	1984:1987	arg2	fiber					1874:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	85	theme	medical	2006:2012	arg1	bandage					2021:2027	bandage	2021:2027	bandage	2021:2027	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	85	theme	medical	2006:2012	arg1	clothing					2041:2048	protective clothing	2030:2048	protective clothing	2030:2048	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	85	theme	medical	2006:2012	arg1	gauze					2014:2018	medical gauze	2006:2018	medical gauze	2006:2018	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	3	86	theme	gap	592:594	arg1	effects					577:583	The effects	573:583	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process	573:669	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	6	87	theme	~48	1457:1459	arg1	%					1460:1460	positive stretching ~48%	1437:1460	positive stretching ~48%	1437:1460	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	88	theme	composite	1864:1872	arg1	better					1884:1889	better	1884:1889	better	1884:1889	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	7	88	theme	composite	1864:1872	arg1	fiber					1874:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber	1848:1878	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	89	theme	3.41	1618:1621	arg1	cN·dtex-1					1623:1631	breaking strength 3.41 cN·dtex-1	1600:1631	breaking strength 3.41 cN·dtex-1	1600:1631	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	90	theme	relative	1769:1776	arg1	%					1789:1789	relative humidity 65%	1769:1789	relative humidity 65%	1769:1789	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	3	91	theme	drawing	619:625	arg1	effects					577:583	The effects	573:583	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process	573:669	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	6	92	theme	positive	1437:1444	arg1	%					1460:1460	positive stretching ~48%	1437:1460	positive stretching ~48%	1437:1460	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	93	theme	breaking	1600:1607	arg1	cN·dtex-1					1623:1631	breaking strength 3.41 cN·dtex-1	1600:1631	breaking strength 3.41 cN·dtex-1	1600:1631	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	94	theme	St	1224:1225	arg1	%					1231:1231	St ~9.8%	1224:1231	St ~9.8%	1224:1231	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	95	theme	DMSO	1273:1276	arg1	solution					1278:1285	DMSO solution	1273:1285	DMSO solution with 6.0 wt% in concentration	1273:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	96	theme	thermal-setting	1508:1522	arg1	~35 mm					1368:1373	air gap ~35 mm	1360:1373	air gap ~35 mm	1360:1373	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	5	97	theme	orientation	1028:1038	arg1	instrument					1040:1049	Single fiber strength tester and sonic orientation instrument	989:1049	instrument	1040:1049	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	4	98	theme	solid	744:748	arg1	state					750:754	solid state nuclear magnetic resonance (13C NMR)	744:791	solid state nuclear magnetic resonance (13C NMR)	744:791	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	99	theme	sonic	1662:1666	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	99	theme	sonic	1662:1666	arg1	factor					1680:1685	sonic orientation factor 0.625	1662:1691	sonic orientation factor 0.625	1662:1691	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	8	100	theme	compatibilization	2098:2114	arg1	method					2116:2121	The in-situ compatibilization method	2086:2121	The in-situ compatibilization method	2086:2121	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	6	101	theme	water	1805:1809	arg1	%					1831:1831	boiling water shrinkage ratio 9.60%	1797:1831	boiling water shrinkage ratio 9.60%	1797:1831	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	102	theme	stretching	1479:1488	arg1	times					1492:1496	stretching 6 times	1479:1496	stretching 6 times at 80 °C	1479:1505	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	4	103	theme	copolymer	963:971	arg1	morphology					945:954	morphology	945:954	morphology	945:954	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	103	theme	copolymer	963:971	arg1	structure					931:939	the structure	927:939	the structure	927:939	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	7	104	theme	fiber	1943:1947	arg1	cN·dtex-1					1955:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	cotton fiber ~3.24 cN·dtex-1	1936:1963	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	105	theme	elongation	1643:1652	arg1	%					1659:1659	breaking elongation 14.41%	1634:1659	breaking elongation 14.41%	1634:1659	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	105	theme	elongation	1643:1652	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	4	106	theme	13C	784:786	arg1	resonance					773:781	nuclear magnetic resonance	756:781	solid state nuclear magnetic resonance (13C NMR)	744:791	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	106	theme	13C	784:786	arg1	NMR					788:790	13C NMR	784:790	13C NMR	784:790	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	5	107	theme	mechanical	1087:1096	arg1	properties					1098:1107	the fiber mechanical properties	1077:1107	the fiber mechanical properties	1077:1107	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	6	108	theme	constant	1547:1554	arg1	mode					1563:1566	constant length mode	1547:1566	constant length mode	1547:1566	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	2	109	theme	dry-wet	545:551	arg1	technique					562:570	dry-wet spinning technique	545:570	dry-wet spinning technique	545:570	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	0	110	theme	compatibilized	8:21	arg1	fiber					57:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	8	111	theme	in-situ	2090:2096	arg1	method					2116:2121	The in-situ compatibilization method	2086:2121	The in-situ compatibilization method	2086:2121	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	4	112	dep	state	750:754	arg1	resonance					773:781	nuclear magnetic resonance	756:781	solid state nuclear magnetic resonance (13C NMR)	744:791	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	112	dep	state	750:754	arg1	NMR					788:790	13C NMR	784:790	13C NMR	784:790	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	113	theme	nuclear	756:762	arg1	resonance					773:781	nuclear magnetic resonance	756:781	solid state nuclear magnetic resonance (13C NMR)	744:791	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	113	theme	nuclear	756:762	arg1	NMR					788:790	13C NMR	784:790	13C NMR	784:790	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	0	114	theme	composite	47:55	arg1	fiber					57:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber	0:61	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	2	115	theme	St/St-g-PAN/PAN/DMSO	439:458	arg1	solution					469:476	St/St-g-PAN/PAN/DMSO spinning solution	439:476	St/St-g-PAN/PAN/DMSO spinning solution	439:476	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	6	116	theme	recovery	1703:1710	arg1	%					1723:1723	moisture recovery ratio 10.53%	1694:1723	moisture recovery ratio 10.53%	1694:1723	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	6	116	theme	recovery	1703:1710	arg1	met					1573:1575	met	1573:1575	met	1573:1575	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	7	117	theme	common	2069:2074	arg1	textiles					2076:2083	common textiles	2069:2083	common textiles	2069:2083	The as prepared composite fiber was better than common viscose fiber 2.11 cN·dtex-1 and cotton fiber ~3.24 cN·dtex-1 and expected to be used in the fields of medical gauze, bandage, protective clothing, et al. besides of common textiles.					
35577192	6	118	theme	gap	1364:1366	arg1	~35 mm					1368:1373	air gap ~35 mm	1360:1373	air gap ~35 mm	1360:1373	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	1	119	theme	ammonium	341:348	arg1	nitrate					357:363	ammonium cerium nitrate	341:363	ammonium cerium nitrate (CAN)	341:369	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	5	120	theme	fiber	996:1000	arg1	tester					1011:1016	Single fiber strength tester and sonic orientation instrument	989:1049	tester	1011:1016	Single fiber strength tester and sonic orientation instrument were performed to measure the fiber mechanical properties and orientation degrees.					
35577192	2	121	theme	St/St-g-PAN/PAN	495:509	arg1	fibers					521:526	St/St-g-PAN/PAN composite fibers	495:526	St/St-g-PAN/PAN composite fibers	495:526	As dimethyl sulfoxide (DMSO) was used as the solvent, St/St-g-PAN/PAN/DMSO spinning solution was prepared and St/St-g-PAN/PAN composite fibers were obtained by dry-wet spinning technique.					
35577192	3	122	theme	process	663:669	arg1	effects					577:583	The effects	573:583	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process	573:669	The effects of air gap, coagulation bath, hot drawing and stretching, and thermal-setting process were studied in detail.					
35577192	0	123	theme	dry-wet	78:84	arg1	technique					95:103	dry-wet spinning technique	78:103	dry-wet spinning technique	78:103	In-situ compatibilized starch/polyacylonitrile composite fiber fabricated via dry-wet spinning technique.					
35577192	4	124	theme	X-ray	828:832	arg1	XRD					856:858	XRD	856:858	XRD	856:858	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	124	theme	X-ray	828:832	arg1	analysis					846:853	X-ray diffraction analysis	828:853	X-ray diffraction analysis (XRD)	828:859	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	125	theme	thermogravimetric	794:810	arg1	TGA					822:824	TGA	822:824	TGA	822:824	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	4	125	theme	thermogravimetric	794:810	arg1	analysis					812:819	thermogravimetric analysis	794:819	thermogravimetric analysis (TGA)	794:825	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35577192	6	126	from	%	1248:1248	arg1	solution					1278:1285	DMSO solution	1273:1285	DMSO solution with 6.0 wt% in concentration	1273:1315	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	8	127	theme	other	2156:2160	arg1	materials					2180:2188	other composite polymer materials	2156:2188	other composite polymer materials	2156:2188	The in-situ compatibilization method can be applied in preparation of other composite polymer materials.					
35577192	1	128	theme	graft	276:280	arg1	acrylonitrile					297:309	graft copolymerizing acrylonitrile	276:309	graft copolymerizing acrylonitrile from soluble starch	276:329	An in-situ compatibilized starch (St) and polyacrylonitrile (PAN) composite spinning solution was designed by preparing starch-graft-polyacrylonitrile (St-g-PAN) through graft copolymerizing acrylonitrile from soluble starch and using ammonium cerium nitrate (CAN) as initiator.					
35577192	6	129	theme	bath	1388:1391	arg1	%					1410:1410	coagulation bath concentration ~70%	1376:1410	coagulation bath concentration ~70%	1376:1410	The results showed that as the grafting ratio ~150.0% and the reacting mixture containing St ~9.8%, St-g-PAN ~81.6%, and homo-PAN ~8.6% in DMSO solution with 6.0 wt% in concentration were used, the spinning parameters such as air gap ~35 mm, coagulation bath concentration ~70%, temperature ~25 °C, and positive stretching ~48%, hot drawing and stretching 6 times at 80 °C, thermal-setting at 90 °C for 3 h under constant length mode were met, composite fibers with breaking strength 3.41 cN·dtex-1, breaking elongation 14.41%, sonic orientation factor 0.625, moisture recovery ratio 10.53% under standard condition (1 atm, 22 °C, and relative humidity 65%), and boiling water shrinkage ratio 9.60% were obtained.					
35577192	4	130	used	used	906:909	arg2	Fourier					695:701	Fourier	695:701	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM)	695:899	Fourier transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (13C NMR), thermogravimetric analysis (TGA), X-ray diffraction analysis (XRD), and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the copolymer and the fibers.					
35717483	7	0	theme	tetanus	1120:1126	arg1	response					1137:1144	tetanus antibody response	1120:1144	tetanus antibody response	1120:1144	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	2	1	theme	early-life	321:330	arg1	microbiome					336:345	the early-life gut microbiome	317:345	the early-life gut microbiome	317:345	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	1	2	theme	vaccine	219:225	arg1	response					227:234	vaccine response	219:234	vaccine response	219:234	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	7	3	from	species	1057:1063	arg1	stool					1098:1102	6-week stool	1091:1102	6-week stool associated with tetanus antibody response	1091:1144	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	3	4	theme	Cohort	492:497	arg1	Study					499:503	the New Hampshire Birth Cohort Study	468:503	the New Hampshire Birth Cohort Study	468:503	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study were included in the analysis.					
35717483	9	5	theme	intestinal	1476:1485	arg1	acquisition					1498:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	10	6	theme	vaccines-pneumococcal	1725:1745	arg1	polysaccharide					1756:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	7	7	theme	6-week	1091:1096	arg1	stool					1098:1102	6-week stool	1091:1102	6-week stool associated with tetanus antibody response	1091:1144	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	1	8	from	influence	206:214	arg1	response					227:234	vaccine response	219:234	vaccine response	219:234	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	10	9	theme	microbiome	1659:1668	arg1	composition					1670:1680	microbiome composition	1659:1680	microbiome composition	1659:1680	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	11	10	theme	infant	1900:1905	arg1	response					1914:1921	infant immune response	1900:1921	infant immune response that may open up opportunities for future interventions	1900:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	5	11	theme	samples	827:833	arg1	subset					814:819	a subset	812:819	a subset of 61 samples	812:833	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	11	12	from	impact	1868:1873	arg1	response					1914:1921	infant immune response	1900:1921	infant immune response that may open up opportunities for future interventions	1900:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	10	13	theme	early	1648:1652	arg1	life					1654:1657	early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age	1648:1828	life	1654:1657	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	11	14	theme	microbiome	1886:1895	arg1	impact					1868:1873	the potential impact	1854:1873	the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions	1854:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	1	15	theme	immune	178:183	arg1	system					185:190	the developing immune system	163:190	the developing immune system	163:190	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	6	16	theme	beta	924:927	arg1	diversity					929:937	beta diversity	924:937	beta diversity	924:937	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	6	17	dep	RESULTS	889:895	arg1	observed					900:907	observed	900:907	observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses	900:1021	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	9	18	theme	IMPACT	1463:1468	arg1	acquisition					1498:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	9	19	theme	immune	1535:1540	arg1	maturation					1542:1551	immune maturation	1535:1551	immune maturation	1535:1551	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	7	20	theme	Metagenomics	1024:1035	arg1	analyses					1037:1044	Metagenomics analyses	1024:1044	Metagenomics analyses	1024:1044	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	2	21	dep	composition	288:298	arg1	the					284:286	the	284:286	the	284:286	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	1	22	theme	gut	118:120	arg1	microbiome					122:131	the gut microbiome	114:131	the gut microbiome	114:131	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	1	23	dep	BACKGROUND	82:91	arg1	establishment					97:109	The establishment	93:109	BACKGROUND The establishment of the gut microbiome	82:131	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	7	24	theme	species	1239:1245	arg1	abundance					1202:1210	the relative abundance	1189:1210	the relative abundance of Aeriscardovia aeriphila species	1189:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	4	25	theme	capsular	674:681	arg1	polysaccharide					683:696	pneumococcal capsular polysaccharide	661:696	pneumococcal capsular polysaccharide	661:696	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	7	26	theme	Aeriscardovia	1215:1227	arg1	species					1239:1245	Aeriscardovia aeriphila species	1215:1245	Aeriscardovia aeriphila species	1215:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	5	27	theme	shotgun	856:862	arg1	sequencing					877:886	shotgun metagenomics sequencing	856:886	shotgun metagenomics sequencing	856:886	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	2	28	from	composition	288:298	arg1	relation					350:357	relation	350:357	relation to infant antibody response to two routinely administered vaccines	350:424	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	6	29	dep	microbiota	960:969	arg1	responses					1013:1021	IgG antibody responses	1000:1021	IgG antibody responses	1000:1021	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	8	30	theme	early	1386:1390	arg1	composition					1407:1417	The early gut microbiome composition	1382:1417	The early gut microbiome composition	1382:1417	CONCLUSIONS The early gut microbiome composition may influence an infant's vaccine response.					
35717483	5	31	theme	Stool	718:722	arg1	samples					724:730	Stool samples	718:730	Stool samples	718:730	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	6	32	theme	6-week	947:952	arg1	microbiota					960:969	6-week stool microbiota	947:969	6-week stool microbiota	947:969	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	8	33	theme	microbiome	1396:1405	arg1	composition					1407:1417	The early gut microbiome composition	1382:1417	The early gut microbiome composition	1382:1417	CONCLUSIONS The early gut microbiome composition may influence an infant's vaccine response.					
35717483	2	34	theme	antibody	369:376	arg1	response					378:385	infant antibody response	362:385	infant antibody response to two routinely administered vaccines	362:424	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	10	35	theme	administered	1712:1723	arg1	polysaccharide					1756:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	7	36	from	pathways	1079:1086	arg1	stool					1098:1102	6-week stool	1091:1102	6-week stool associated with tetanus antibody response	1091:1144	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	5	37	theme	16S	798:800	arg1	rRNA					802:805	16S rRNA	798:805	16S rRNA	798:805	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	7	38	theme	CDP-diacylglycerol	1328:1345	arg1	pathways					1360:1367	CDP-diacylglycerol biosynthesis pathways	1328:1367	CDP-diacylglycerol biosynthesis pathways	1328:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	4	39	theme	blood	549:553	arg1	samples					555:561	blood samples	549:561	blood samples	549:561	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	9	40	theme	microbiome	1487:1496	arg1	acquisition					1498:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	6	41	theme	antibody	1004:1011	arg1	responses					1013:1021	IgG antibody responses	1000:1021	IgG antibody responses	1000:1021	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	3	42	theme	Hampshire	476:484	arg1	Cohort					492:497	the New Hampshire Birth Cohort	468:497	the New Hampshire Birth Cohort Study	468:503	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study were included in the analysis.					
35717483	5	43	theme	age	774:776	arg1	weeks					765:769	6 weeks	763:769	6 weeks of age	763:776	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	7	44	theme	relative	1282:1289	arg1	abundance					1291:1299	the relative abundance	1278:1299	the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways	1278:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	4	45	theme	age	579:581	arg1	months					569:574	12 months	566:574	12 months of age	566:581	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	2	46	theme	gut	332:334	arg1	microbiome					336:345	the early-life gut microbiome	317:345	the early-life gut microbiome	317:345	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	2	47	from	diversity	304:312	arg1	relation					350:357	relation	350:357	relation to infant antibody response to two routinely administered vaccines	350:424	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	7	48	theme	positive	1251:1258	arg1	associations					1260:1271	positive associations	1251:1271	positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways	1251:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	7	49	with	associations	1260:1271	arg1	abundance					1202:1210	the relative abundance	1189:1210	the relative abundance of Aeriscardovia aeriphila species	1189:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	7	49	with	associations	1260:1271	arg1	abundance					1291:1299	the relative abundance	1278:1299	the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways	1278:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	9	50	theme	Early	1470:1474	arg1	acquisition					1498:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition	1463:1508	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	10	51	from	year	1818:1821	arg1	response					1686:1693	response	1686:1693	response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age	1686:1828	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	10	51	from	year	1818:1821	arg1	life					1654:1657	early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age	1648:1828	life	1654:1657	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	10	52	dep	life	1654:1657	arg1	composition					1670:1680	microbiome composition	1659:1680	microbiome composition	1659:1680	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	1	53	theme	symbiotic	145:153	arg1	role					155:158	a key symbiotic role	139:158	a key symbiotic role	139:158	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	0	54	theme	gut	34:36	arg1	study					14:18	A prospective study	0:18	A prospective study of the infant gut	0:36	A prospective study of the infant gut microbiome in relation to vaccine response.					
35717483	4	55	theme	total	626:630	arg1	IgG					632:634	total IgG	626:634	total IgG	626:634	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	7	56	theme	metabolic	1069:1077	arg1	pathways					1079:1086	metabolic pathways	1069:1086	metabolic pathways	1069:1086	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	11	57	theme	immune	1907:1912	arg1	response					1914:1921	infant immune response	1900:1921	infant immune response that may open up opportunities for future interventions	1900:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	1	58	theme	developing	167:176	arg1	system					185:190	the developing immune system	163:190	the developing immune system	163:190	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	7	59	with	associations	1171:1182	arg1	abundance					1202:1210	the relative abundance	1189:1210	the relative abundance of Aeriscardovia aeriphila species	1189:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	7	59	with	associations	1171:1182	arg1	abundance					1291:1299	the relative abundance	1278:1299	the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways	1278:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	9	60	theme	immune	1585:1590	arg1	response					1592:1599	both adaptive and innate immune response	1560:1599	both adaptive and innate immune response in infancy	1560:1610	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	4	61	theme	isolated	599:606	arg1	serum					608:612	the isolated serum to quantify total IgG	595:634	the isolated serum to quantify total IgG	595:634	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	11	62	theme	future	1958:1963	arg1	interventions					1965:1977	future interventions	1958:1977	future interventions	1958:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	9	63	from	response	1592:1599	arg1	infancy					1604:1610	infancy	1604:1610	infancy	1604:1610	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	5	64	theme	metagenomics	864:875	arg1	sequencing					877:886	shotgun metagenomics sequencing	856:886	shotgun metagenomics sequencing	856:886	Stool samples were collected from infants at 6 weeks of age and sequenced using 16S rRNA, and a subset of 61 samples were sequenced using shotgun metagenomics sequencing.					
35717483	6	65	theme	IgG	1000:1002	arg1	responses					1013:1021	IgG antibody responses	1000:1021	IgG antibody responses	1000:1021	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	4	66	theme	tetanus	702:708	arg1	toxoid					710:715	tetanus toxoid	702:715	tetanus toxoid	702:715	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	11	67	theme	potential	1858:1866	arg1	impact					1868:1873	the potential impact	1854:1873	the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions	1854:1977	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	7	68	theme	aeriphila	1229:1237	arg1	species					1239:1245	Aeriscardovia aeriphila species	1215:1245	Aeriscardovia aeriphila species	1215:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	9	69	theme	critical	1518:1525	arg1	role					1527:1530	a critical role	1516:1530	a critical role	1516:1530	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	9	70	theme	adaptive	1565:1572	arg1	response					1592:1599	both adaptive and innate immune response	1560:1599	both adaptive and innate immune response in infancy	1560:1610	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	0	71	theme	vaccine	64:70	arg1	response					72:79	vaccine response	64:79	vaccine response	64:79	A prospective study of the infant gut microbiome in relation to vaccine response.					
35717483	9	72	theme	innate	1578:1583	arg1	response					1592:1599	both adaptive and innate immune response	1560:1599	both adaptive and innate immune response in infancy	1560:1610	IMPACT Early intestinal microbiome acquisition plays a critical role in immune maturation and in both adaptive and innate immune response in infancy.					
35717483	4	73	theme	pneumococcal	661:672	arg1	polysaccharide					683:696	pneumococcal capsular polysaccharide	661:696	pneumococcal capsular polysaccharide	661:696	We collected blood samples at 12 months of age and assayed the isolated serum to quantify total IgG and measured antibody to pneumococcal capsular polysaccharide and tetanus toxoid.					
35717483	11	74	theme	gut	1882:1884	arg1	microbiome					1886:1895	the gut microbiome	1878:1895	the gut microbiome	1878:1895	Our findings highlight the potential impact of the gut microbiome on infant immune response that may open up opportunities for future interventions.					
35717483	7	75	theme	relative	1193:1200	arg1	abundance					1202:1210	the relative abundance	1189:1210	the relative abundance of Aeriscardovia aeriphila species	1189:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	6	76	theme	stool	954:958	arg1	microbiota					960:969	6-week stool microbiota	947:969	6-week stool microbiota	947:969	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	1	77	theme	key	141:143	arg1	role					155:158	a key symbiotic role	139:158	a key symbiotic role	139:158	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	8	78	theme	gut	1392:1394	arg1	composition					1407:1417	The early gut microbiome composition	1382:1417	The early gut microbiome composition	1382:1417	CONCLUSIONS The early gut microbiome composition may influence an infant's vaccine response.					
35717483	2	79	theme	infant	362:367	arg1	response					378:385	infant antibody response	362:385	infant antibody response to two routinely administered vaccines	362:424	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	0	80	theme	prospective	2:12	arg1	study					14:18	A prospective study	0:18	A prospective study of the infant gut	0:36	A prospective study of the infant gut microbiome in relation to vaccine response.					
35717483	7	81	theme	biosynthesis	1347:1358	arg1	pathways					1360:1367	CDP-diacylglycerol biosynthesis pathways	1328:1367	CDP-diacylglycerol biosynthesis pathways	1328:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	2	82	theme	administered	404:415	arg1	vaccines					417:424	two routinely administered vaccines	390:424	two routinely administered vaccines	390:424	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	10	83	theme	tetanus	1775:1781	arg1	toxoid-measured					1783:1797	tetanus toxoid-measured	1775:1797	tetanus toxoid-measured	1775:1797	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	0	84	theme	infant	27:32	arg1	gut					34:36	the infant gut	23:36	the infant gut	23:36	A prospective study of the infant gut microbiome in relation to vaccine response.					
35717483	8	85	dep	CONCLUSIONS	1370:1380	arg1	influence					1423:1431	influence	1423:1431	may influence an infant's vaccine response	1419:1460	CONCLUSIONS The early gut microbiome composition may influence an infant's vaccine response.					
35717483	7	86	theme	species	1304:1310	arg1	abundance					1291:1299	the relative abundance	1278:1299	the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways	1278:1367	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	10	87	theme	capsular	1747:1754	arg1	polysaccharide					1756:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	two routinely administered vaccines-pneumococcal capsular polysaccharide	1698:1769	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	7	88	theme	antibody	1128:1135	arg1	response					1137:1144	tetanus antibody response	1120:1144	tetanus antibody response	1120:1144	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
35717483	2	89	theme	microbiome	336:345	arg1	diversity					304:312	diversity	304:312	diversity	304:312	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	2	89	theme	microbiome	336:345	arg1	composition					288:298	composition	288:298	composition	288:298	We prospectively investigated the composition and diversity of the early-life gut microbiome in relation to infant antibody response to two routinely administered vaccines.					
35717483	8	90	theme	vaccine	1445:1451	arg1	response					1453:1460	an infant's vaccine response	1433:1460	an infant's vaccine response	1433:1460	CONCLUSIONS The early gut microbiome composition may influence an infant's vaccine response.					
35717483	3	91	theme	Birth	486:490	arg1	Cohort					492:497	the New Hampshire Birth Cohort	468:497	the New Hampshire Birth Cohort Study	468:503	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study were included in the analysis.					
35717483	1	92	theme	microbiome	122:131	arg1	establishment					97:109	The establishment	93:109	BACKGROUND The establishment of the gut microbiome	82:131	BACKGROUND The establishment of the gut microbiome plays a key symbiotic role in the developing immune system; however, its influence on vaccine response is yet uncertain.					
35717483	6	93	from	differences	909:919	arg1	diversity					929:937	beta diversity	924:937	beta diversity	924:937	RESULTS We observed differences in beta diversity for 16S 6-week stool microbiota and pneumococcal and tetanus IgG antibody responses.					
35717483	3	94	theme	New	472:474	arg1	Cohort					492:497	the New Hampshire Birth Cohort	468:497	the New Hampshire Birth Cohort Study	468:503	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study were included in the analysis.					
35717483	10	95	theme	age	1826:1828	arg1	year					1818:1821	approximately 1 year	1802:1821	approximately 1 year of age	1802:1828	We identified associations between early life microbiome composition and response to two routinely administered vaccines-pneumococcal capsular polysaccharide and tetanus toxoid-measured at approximately 1 year of age.					
35717483	3	96	theme	METHODS	427:433	arg1	infants					448:454	METHODS Eighty-three infants	427:454	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study	427:503	METHODS Eighty-three infants enrolled in the New Hampshire Birth Cohort Study were included in the analysis.					
35717483	7	97	theme	negative	1162:1169	arg1	associations					1171:1182	negative associations	1162:1182	negative associations with the relative abundance of Aeriscardovia aeriphila species	1162:1245	Metagenomics analyses identified species and metabolic pathways in 6-week stool associated with tetanus antibody response, in particular, negative associations with the relative abundance of Aeriscardovia aeriphila species and positive associations with the relative abundance of species associated with CDP-diacylglycerol biosynthesis pathways.					
36883964	5	0	theme	Theory	790:795	arg1	simulation					803:812	The experimental results and Density Function Theory (DFT) simulation	744:812	The experimental results and Density Function Theory (DFT) simulation	744:812	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	5	0	theme	Theory	790:795	arg1	DFT					798:800	DFT	798:800	DFT	798:800	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	1	1	theme	lithium-metal	125:137	arg1	batteries					139:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	1	1	theme	lithium-metal	125:137	arg1	generation					176:185	the next generation	167:185	the next generation of high-energy-density batteries	167:218	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	1	2	theme	high-energy-density	190:208	arg1	batteries					210:218	high-energy-density batteries	190:218	high-energy-density batteries	190:218	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	4	3	theme	|||C-CLA|	613:618	arg1	batteries					627:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	1	4	theme	batteries	210:218	arg1	batteries					139:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	1	4	theme	batteries	210:218	arg1	generation					176:185	the next generation	167:185	the next generation of high-energy-density batteries	167:218	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	6	5	theme	cost-effective	1014:1027	arg1	electrolytes					1045:1056	cost-effective, stable polymer electrolytes	1014:1056	cost-effective, stable polymer electrolytes	1014:1056	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	3	6	theme	acetate-based	417:429	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	6	theme	acetate-based	417:429	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	6	7	dep	cost-effective	1014:1027	arg1	stable					1030:1035	stable	1030:1035	stable	1030:1035	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	5	8	theme	results	761:767	arg1	simulation					803:812	The experimental results and Density Function Theory (DFT) simulation	744:812	The experimental results and Density Function Theory (DFT) simulation	744:812	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	5	8	theme	results	761:767	arg1	DFT					798:800	DFT	798:800	DFT	798:800	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	3	9	theme	quasi-solid	431:441	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	9	theme	quasi-solid	431:441	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	2	10	theme	production	328:337	arg1	costs					339:343	high production costs	323:343	high production costs	323:343	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	4	11	theme	|QPE||Li|	620:625	arg1	batteries					627:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	3	12	theme	low-cost	398:405	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	12	theme	low-cost	398:405	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	2	13	theme	high	323:326	arg1	costs					339:343	high production costs	323:343	high production costs	323:343	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	5	14	theme	CLA	872:874	arg1	matrix					876:881	the CLA matrix	868:881	the CLA matrix	868:881	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	3	15	theme	cellulose	407:415	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	15	theme	cellulose	407:415	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	6	16	theme	promising	979:987	arg1	strategy					989:996	a promising strategy	977:996	a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries	977:1090	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	3	17	theme	high	506:509	arg1	tLi+					537:540	tLi+	537:540	tLi+	537:540	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	17	theme	high	506:509	arg1	Li					511:512	high Li	506:512	high Li	506:512	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	5	18	theme	Density	773:779	arg1	Theory					790:795	Density Function Theory	773:795	Density Function Theory	773:795	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	1	19	theme	Solid-state	113:123	arg1	batteries					139:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	1	19	theme	Solid-state	113:123	arg1	generation					176:185	the next generation	167:185	the next generation of high-energy-density batteries	167:218	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	0	20	theme	Low-Cost	0:7	arg1	Polymer					52:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer	0:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer	0:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer Electrolyte for Solid-State Lithium-Metal Batteries.					
36883964	2	21	theme	commercial	364:373	arg1	application					375:385	restricting their commercial application	346:385	restricting their commercial application	346:385	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	4	22	theme	%	708:708	arg1	retention					691:699	a capacity retention	680:699	a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃	680:741	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	3	23	theme	composite	443:451	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	23	theme	composite	443:451	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	4	24	theme	LiFePO	599:604	arg1	batteries					627:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	5	25	theme	electrochemical	931:945	arg1	stability					947:955	electrochemical stability	931:955	electrochemical stability	931:955	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	2	26	theme	restricting their	346:362	arg1	application					375:385	restricting their commercial application	346:385	restricting their commercial application	346:385	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	3	27	theme	transference	516:527	arg1	number					529:534	transference number	516:534	transference number	516:534	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	28	theme	polymer	453:459	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	28	theme	polymer	453:459	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	4	29	theme	LFP	609:611	arg1	batteries					627:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	3	30	theme	stability	575:583	arg1	tLi+					537:540	tLi+	537:540	tLi+	537:540	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	30	theme	stability	575:583	arg1	Li					511:512	high Li	506:512	high Li	506:512	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	5	31	theme	Li	914:915	arg1	migration					901:909	the migration	897:909	the migration of Li +	897:917	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	3	32	theme	0.85	546:549	arg1	tLi+					537:540	tLi+	537:540	tLi+	537:540	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	32	theme	0.85	546:549	arg1	Li					511:512	high Li	506:512	high Li	506:512	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	6	33	theme	lithium	1074:1080	arg1	batteries					1082:1090	solid-state lithium batteries	1062:1090	solid-state lithium batteries	1062:1090	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	0	34	theme	Quasi-Solid	40:50	arg1	Polymer					52:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer	0:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer	0:58	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer Electrolyte for Solid-State Lithium-Metal Batteries.					
36883964	5	35	theme	experimental	748:759	arg1	results					761:767	The experimental results	744:767	The experimental results	744:767	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	4	36	theme	capacity	682:689	arg1	retention					691:699	a capacity retention	680:699	a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃	680:741	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	3	37	theme	C-CLA	474:478	arg1	electrolyte					461:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte	396:471	a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE)	396:483	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	3	37	theme	C-CLA	474:478	arg1	QPE					480:482	C-CLA QPE	474:482	C-CLA QPE	474:482	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	6	38	theme	solid-state	1062:1072	arg1	batteries					1082:1090	solid-state lithium batteries	1062:1090	solid-state lithium batteries	1062:1090	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	5	39	theme	Function	781:788	arg1	Theory					790:795	Density Function Theory	773:795	Density Function Theory	773:795	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	2	40	theme	ionic	271:275	arg1	conductivity					277:288	low ionic conductivity	267:288	low ionic conductivity	267:288	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	4	41	theme	prepared	590:597	arg1	batteries					627:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries|	586:635	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	2	42	theme	low	267:269	arg1	conductivity					277:288	low ionic conductivity	267:288	low ionic conductivity	267:288	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	0	43	dep	Low-Cost	0:7	arg1	Cellulose-based					24:38	Cellulose-based	24:38	Cellulose-based	24:38	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer Electrolyte for Solid-State Lithium-Metal Batteries.					
36883964	3	44	dep	Li	511:512	arg1	a					504:504	a	504:504	a	504:504	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	5	45	from	groups	858:863	arg1	matrix					876:881	the CLA matrix	868:881	the CLA matrix	868:881	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	4	46	from	25℃	739:741	arg1	cycles					721:726	1200 cycles	716:726	1200 cycles at 1 C and 25℃	716:741	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	4	47	theme	excellent	647:655	arg1	performance					663:673	excellent cycle performance	647:673	excellent cycle performance	647:673	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	5	48	theme	esterified	842:851	arg1	groups					858:863	the partially esterified side groups	828:863	the partially esterified side groups in the CLA matrix	828:881	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	1	49	theme	next	171:174	arg1	batteries					139:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries	113:147	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	1	49	theme	next	171:174	arg1	generation					176:185	the next generation	167:185	the next generation of high-energy-density batteries	167:218	Solid-state lithium-metal batteries are considered as the next generation of high-energy-density batteries.					
36883964	0	50	theme	Lithium-Metal	88:100	arg1	Batteries					102:110	Solid-State Lithium-Metal Batteries	76:110	Solid-State Lithium-Metal Batteries	76:110	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer Electrolyte for Solid-State Lithium-Metal Batteries.					
36883964	2	51	theme	solid	236:240	arg1	electrolytes					242:253	their solid electrolytes	230:253	their solid electrolytes	230:253	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	2	52	theme	interface	296:304	arg1	performance					306:316	poor interface performance	291:316	poor interface performance	291:316	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	5	53	theme	side	853:856	arg1	groups					858:863	the partially esterified side groups	828:863	the partially esterified side groups in the CLA matrix	828:881	The experimental results and Density Function Theory (DFT) simulation revealed that the partially esterified side groups in the CLA matrix contribute to the migration of Li + and enhance electrochemical stability.					
36883964	3	54	theme	excellent	555:563	arg1	stability					575:583	excellent interface stability	555:583	excellent interface stability	555:583	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	4	55	from	C	733:733	arg1	cycles					721:726	1200 cycles	716:726	1200 cycles at 1 C and 25℃	716:741	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
36883964	6	56	theme	polymer	1037:1043	arg1	electrolytes					1045:1056	cost-effective, stable polymer electrolytes	1014:1056	cost-effective, stable polymer electrolytes	1014:1056	This work provides a promising strategy for fabricating cost-effective, stable polymer electrolytes for solid-state lithium batteries.					
36883964	0	57	theme	Solid-State	76:86	arg1	Batteries					102:110	Solid-State Lithium-Metal Batteries	76:110	Solid-State Lithium-Metal Batteries	76:110	Low-Cost, High-Strength Cellulose-based Quasi-Solid Polymer Electrolyte for Solid-State Lithium-Metal Batteries.					
36883964	2	58	theme	poor	291:294	arg1	performance					306:316	poor interface performance	291:316	poor interface performance	291:316	However, their solid electrolytes suffer from low ionic conductivity, poor interface performance, and high production costs, restricting their commercial application.					
36883964	3	59	theme	interface	565:573	arg1	stability					575:583	excellent interface stability	555:583	excellent interface stability	555:583	Herein, a low-cost cellulose acetate-based quasi-solid composite polymer electrolyte (C-CLA QPE) was developed with a high Li + transference number (tLi+) of 0.85 and excellent interface stability.					
36883964	4	60	theme	cycle	657:661	arg1	performance					663:673	excellent cycle performance	647:673	excellent cycle performance	647:673	|The prepared LiFePO 4 (LFP)||C-CLA QPE||Li batteries exhibited excellent cycle performance with a capacity retention of 97.7% after 1200 cycles at 1 C and 25℃.|					
35627825	0	0	theme	Dust	84:87	arg1	Suppressant					89:99	New Nano-Composite Dust Suppressant	65:99	New Nano-Composite Dust Suppressant	65:99	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	5	1	contain	has	1079:1081	arg2	dispersion					1088:1097	good dispersion	1083:1097	good dispersion	1083:1097	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	1	contain	has	1079:1081	arg2	permeability					1100:1111	permeability	1100:1111	permeability	1100:1111	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	1	contain	has	1079:1081	arg1	suppressant					1067:1077	the nano-composite dust suppressant	1043:1077	the nano-composite dust suppressant	1043:1077	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	1	contain	has	1079:1081	arg2	performance					1122:1132	bond performance	1117:1132	bond performance	1117:1132	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	4	2	theme	water	844:848	arg1	rates					855:859	water loss rates	844:859	water loss rates	844:859	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	2	3	theme	starch	347:352	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	3	theme	starch	347:352	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	3	theme	starch	347:352	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	3	theme	starch	347:352	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	3	theme	starch	347:352	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	5	4	theme	image	1210:1214	arg1	photos					1188:1193	the photos	1184:1193	the photos of microscopic image	1184:1214	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	0	5	theme	Nano-Composite	69:82	arg1	Suppressant					89:99	New Nano-Composite Dust Suppressant	65:99	New Nano-Composite Dust Suppressant	65:99	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	0	6	from	Study	13:17	arg1	Effect					39:44	Dust Suppression Effect	22:44	Dust Suppression Effect	22:44	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	0	6	from	Study	13:17	arg1	Performance					50:60	Performance	50:60	Performance of New Nano-Composite Dust Suppressant	50:99	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	2	7	theme	methyl	340:345	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	7	theme	methyl	340:345	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	7	theme	methyl	340:345	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	7	theme	methyl	340:345	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	7	theme	methyl	340:345	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	3	8	theme	nano-composite	673:686	arg1	suppressant					693:703	nano-composite dust suppressant	673:703	nano-composite dust suppressant	673:703	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	9	theme	compressive	500:510	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	9	theme	compressive	500:510	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	9	theme	compressive	500:510	arg1	UCS					522:524	UCS	522:524	UCS	522:524	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	9	theme	compressive	500:510	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	9	theme	compressive	500:510	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	2	10	theme	nanometer	280:288	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	10	theme	nanometer	280:288	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	10	theme	nanometer	280:288	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	10	theme	nanometer	280:288	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	10	theme	nanometer	280:288	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	1	11	theme	nanofluid	248:256	arg1	suppressant					263:273	a nanofluid dust suppressant	246:273	a nanofluid dust suppressant	246:273	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	0	12	theme	Suppressant	89:99	arg1	Effect					39:44	Dust Suppression Effect	22:44	Dust Suppression Effect	22:44	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	0	12	theme	Suppressant	89:99	arg1	Performance					50:60	Performance	50:60	Performance of New Nano-Composite Dust Suppressant	50:99	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	5	13	theme	dust	1265:1268	arg1	consolidation					1270:1282	dust consolidation	1265:1282	dust consolidation	1265:1282	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	4	14	theme	loss	850:853	arg1	rates					855:859	water loss rates	844:859	water loss rates	844:859	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	5	15	theme	consolidation	1270:1282	arg1	integrity					1252:1260	integrity	1252:1260	integrity	1252:1260	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	15	theme	consolidation	1270:1282	arg1	compactness					1236:1246	compactness	1236:1246	compactness	1236:1246	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	1	16	theme	dust	258:261	arg1	suppressant					263:273	a nanofluid dust suppressant	246:273	a nanofluid dust suppressant	246:273	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	3	17	theme	surface	714:720	arg1	morphology					722:731	the surface morphology	710:731	the surface morphology of each tested material	710:755	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	4	18	dep	suppressants	888:899	arg1	decreased					916:924	decreased	916:924	decreased by 31.96% and 7.1%	916:943	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	5	19	theme	nano-composite	1047:1060	arg1	suppressant					1067:1077	the nano-composite dust suppressant	1043:1077	the nano-composite dust suppressant	1043:1077	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	2	20	theme	absorbent	312:320	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	20	theme	absorbent	312:320	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	20	theme	absorbent	312:320	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	20	theme	absorbent	312:320	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	20	theme	absorbent	312:320	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	3	21	theme	surface	430:436	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	21	theme	surface	430:436	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	21	theme	surface	430:436	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	21	theme	surface	430:436	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	4	22	dep	tension	832:838	arg1	the					820:822	the	820:822	the	820:822	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	5	23	theme	dust	1062:1065	arg1	suppressant					1067:1077	the nano-composite dust suppressant	1043:1077	the nano-composite dust suppressant	1043:1077	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	24	contain	has	1156:1158	arg1	film					1151:1154	the suppressant film	1135:1154	the suppressant film	1135:1154	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	24	contain	has	1156:1158	arg2	micro-cracks					1166:1177	fewer micro-cracks	1160:1177	fewer micro-cracks	1160:1177	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	2	25	theme	super	306:310	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	25	theme	super	306:310	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	25	theme	super	306:310	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	25	theme	super	306:310	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	25	theme	super	306:310	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	5	26	theme	dust	1324:1327	arg1	evaporation					1299:1309	the evaporation	1295:1309	the evaporation of water and dust re-entrainment	1295:1342	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	0	27	theme	Experimental	0:11	arg1	Study					13:17	Experimental Study	0:17	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.	0:100	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	1	28	theme	suppressant	263:273	arg1	wettability					202:212	wettability	202:212	wettability	202:212	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	1	28	theme	suppressant	263:273	arg1	performance					231:241	moisturizing performance	218:241	moisturizing performance	218:241	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	4	29	theme	surface	824:830	arg1	tension					832:838	surface tension	824:838	surface tension	824:838	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	5	30	theme	good	1083:1086	arg1	dispersion					1088:1097	good dispersion	1083:1097	good dispersion	1083:1097	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	0	31	theme	Dust	22:25	arg1	Effect					39:44	Dust Suppression Effect	22:44	Dust Suppression Effect	22:44	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	3	32	theme	micro	773:777	arg1	analysis					785:792	micro image analysis	773:792	micro image analysis system	773:799	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	2	33	theme	it	422:423	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	33	theme	it	422:423	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	33	theme	it	422:423	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	33	theme	it	422:423	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	33	theme	it	422:423	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	34	theme	material	290:297	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	34	theme	material	290:297	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	34	theme	material	290:297	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	34	theme	material	290:297	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	34	theme	material	290:297	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	3	35	theme	solution	453:460	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	35	theme	solution	453:460	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	35	theme	solution	453:460	arg1	UCS					522:524	UCS	522:524	UCS	522:524	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	35	theme	solution	453:460	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	35	theme	solution	453:460	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	5	36	theme	suppressant	1139:1149	arg1	film					1151:1154	the suppressant film	1135:1154	the suppressant film	1135:1154	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	4	37	theme	suppressants	1023:1034	arg1	data					1000:1003	data	1000:1003	data of nanofluid dust suppressants	1000:1034	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	2	38	theme	effective	398:406	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	38	theme	effective	398:406	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	38	theme	effective	398:406	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	38	theme	effective	398:406	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	38	theme	effective	398:406	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	0	39	theme	Suppression	27:37	arg1	Effect					39:44	Dust Suppression Effect	22:44	Dust Suppression Effect	22:44	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	3	40	theme	suppression	574:584	arg1	performance					586:596	the suppression performance	570:596	the suppression performance	570:596	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	1	41	from	deficiency	188:197	arg1	wettability					202:212	wettability	202:212	wettability	202:212	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	1	41	from	deficiency	188:197	arg1	performance					231:241	moisturizing performance	218:241	moisturizing performance	218:241	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	5	42	theme	bond	1117:1120	arg1	performance					1122:1132	bond performance	1117:1132	bond performance	1117:1132	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	3	43	theme	tested	741:746	arg1	material					748:755	each tested material	736:755	each tested material	736:755	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	2	44	theme	carboxyl	331:338	arg1	components					408:417	effective components	398:417	effective components of it	398:423	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	44	theme	carboxyl	331:338	arg1	polyacrylamide					366:379	polyacrylamide	366:379	polyacrylamide	366:379	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	44	theme	carboxyl	331:338	arg1	sodium					354:359	carboxyl methyl starch sodium	331:359	carboxyl methyl starch sodium	331:359	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	44	theme	carboxyl	331:338	arg1	polymer					322:328	super absorbent polymer	306:328	super absorbent polymer	306:328	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	2	44	theme	carboxyl	331:338	arg1	Al2O3					299:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3	276:303	The nanometer material Al2O3, super absorbent polymer, carboxyl methyl starch sodium, and polyacrylamide were selected as effective components of it.					
35627825	4	45	theme	maximum	954:960	arg1	UCS					962:964	the maximum UCS	950:964	the maximum UCS	950:964	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	3	46	theme	material	748:755	arg1	morphology					722:731	the surface morphology	710:731	the surface morphology of each tested material	710:755	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	47	theme	dust	652:655	arg1	suppressant					657:667	nanofluid dust suppressant	642:667	nanofluid dust suppressant	642:667	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	5	48	dep	water	1314:1318	arg1	re-entrainment					1329:1342	re-entrainment	1329:1342	re-entrainment	1329:1342	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	3	49	theme	uniaxial	491:498	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	49	theme	uniaxial	491:498	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	49	theme	uniaxial	491:498	arg1	UCS					522:524	UCS	522:524	UCS	522:524	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	49	theme	uniaxial	491:498	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	49	theme	uniaxial	491:498	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	4	50	theme	dust	1018:1021	arg1	suppressants					1023:1034	nanofluid dust suppressants	1008:1034	nanofluid dust suppressants	1008:1034	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	3	51	theme	evaluation	542:551	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	51	theme	evaluation	542:551	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	51	theme	evaluation	542:551	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	51	theme	evaluation	542:551	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	4	52	theme	dust	883:886	arg1	tension					832:838	surface tension	824:838	surface tension	824:838	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	4	52	theme	dust	883:886	arg1	rates					855:859	water loss rates	844:859	water loss rates	844:859	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	5	53	dep	compactness	1236:1246	arg1	the					1232:1234	the	1232:1234	the	1232:1234	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	4	54	theme	nanofluid	1008:1016	arg1	suppressants					1023:1034	nanofluid dust suppressants	1008:1034	nanofluid dust suppressants	1008:1034	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	3	55	theme	analysis	785:792	arg1	system					794:799	micro image analysis system	773:799	micro image analysis system	773:799	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	4	56	theme	nano-composite	868:881	arg1	dust					883:886	the nano-composite dust	864:886	the nano-composite dust	864:886	It was found that the surface tension and water loss rates of the nano-composite dust suppressants, respectively, decreased by 31.96% and 7.1%, and the maximum UCS increased by 31.82% compared with data of nanofluid dust suppressants.					
35627825	3	57	theme	dust	605:608	arg1	suppressants					610:621	these dust suppressants	599:621	these dust suppressants	599:621	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	1	58	theme	nano-composite	119:132	arg1	suppressant					139:149	a nano-composite dust suppressant	117:149	a nano-composite dust suppressant	117:149	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	0	59	theme	New	65:67	arg1	Suppressant					89:99	New Nano-Composite Dust Suppressant	65:99	New Nano-Composite Dust Suppressant	65:99	Experimental Study on Dust Suppression Effect and Performance of New Nano-Composite Dust Suppressant.					
35627825	3	60	theme	nanofluid	642:650	arg1	suppressant					657:667	nanofluid dust suppressant	642:667	nanofluid dust suppressant	642:667	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	1	61	theme	dust	134:137	arg1	suppressant					139:149	a nano-composite dust suppressant	117:149	a nano-composite dust suppressant	117:149	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	3	62	theme	evaporation	463:473	arg1	resistance					475:484	evaporation resistance	463:484	evaporation resistance	463:484	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	62	theme	evaporation	463:473	arg1	strength					512:519	uniaxial compressive strength	491:519	uniaxial compressive strength (UCS)	491:525	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	62	theme	evaporation	463:473	arg1	tension					438:444	The surface tension	426:444	The surface tension of the solution	426:460	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	3	62	theme	evaporation	463:473	arg1	index					553:557	evaluation index	542:557	evaluation index	542:557	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	1	63	theme	moisturizing	218:229	arg1	performance					231:241	moisturizing performance	218:241	moisturizing performance	218:241	In this paper, a nano-composite dust suppressant has been proposed to make up for the deficiency in wettability and moisturizing performance of a nanofluid dust suppressant.					
35627825	5	64	theme	fewer	1160:1164	arg1	micro-cracks					1166:1177	fewer micro-cracks	1160:1177	fewer micro-cracks	1160:1177	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	3	65	theme	dust	688:691	arg1	suppressant					693:703	nano-composite dust suppressant	673:703	nano-composite dust suppressant	673:703	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
35627825	5	66	theme	water	1314:1318	arg1	evaporation					1299:1309	the evaporation	1295:1309	the evaporation of water and dust re-entrainment	1295:1342	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	5	67	theme	microscopic	1198:1208	arg1	image					1210:1214	microscopic image	1198:1214	microscopic image	1198:1214	Since the nano-composite dust suppressant has good dispersion, permeability and bond performance, the suppressant film has fewer micro-cracks from the photos of microscopic image; it can improve the compactness and integrity of dust consolidation to prevent the evaporation of water and dust re-entrainment.					
35627825	3	68	theme	image	779:783	arg1	analysis					785:792	micro image analysis	773:792	micro image analysis system	773:799	The surface tension of the solution, evaporation resistance, and uniaxial compressive strength (UCS) were chosen as evaluation index to compare the suppression performance, these dust suppressants include the water, nanofluid dust suppressant and nano-composite dust suppressant, and the surface morphology of each tested material was observed by micro image analysis system.					
37067060	2	0	theme	ammonium	470:477	arg1	chitosan					479:486	polyvinyl alcohol-quaternary ammonium chitosan	441:486	polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS)	441:496	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	0	theme	ammonium	470:477	arg1	PVA-QCS					489:495	PVA-QCS	489:495	PVA-QCS	489:495	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	7	1	theme	multifunctional	1067:1081	arg1	films					1093:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	4	2	theme	film	681:684	arg1	strength					665:672	The tensile strength	653:672	The tensile strength of the film	653:684	The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film.					
37067060	2	3	theme	alcohol-quaternary	451:468	arg1	chitosan					479:486	polyvinyl alcohol-quaternary ammonium chitosan	441:486	polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS)	441:496	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	3	theme	alcohol-quaternary	451:468	arg1	PVA-QCS					489:495	PVA-QCS	489:495	PVA-QCS	489:495	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	7	4	theme	composite	1083:1091	arg1	films					1093:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	5	5	theme	water	828:832	arg1	repellency					834:843	water repellency	828:843	water repellency	828:843	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	2	6	theme	ZIF-8	354:358	arg1	NPs					360:362	RB@ZIF-8 NPs	351:362	RB@ZIF-8 NPs	351:362	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	6	theme	ZIF-8	354:358	arg1	substrates					501:510	substrates	501:510	substrates	501:510	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	0	7	theme	antibacterial	108:120	arg1	activities					122:131	efficient antibacterial activities	98:131	efficient antibacterial activities	98:131	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	2	8	theme	Bengal	311:316	arg1	stability					273:281	the poor stability	264:281	the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ)	264:540	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	0	9	theme	efficient	98:106	arg1	activities					122:131	efficient antibacterial activities	98:131	efficient antibacterial activities	98:131	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	7	10	theme	PQZ	1063:1065	arg1	films					1093:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films	1063:1097	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	2	11	theme	Rose	306:309	arg1	RB					319:320	RB	319:320	RB	319:320	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	11	theme	Rose	306:309	arg1	Bengal					311:316	the photosensitizer Rose Bengal	286:316	the photosensitizer Rose Bengal (RB)	286:321	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	1	12	theme	Antibacterial	134:146	arg1	therapy					161:167	Antibacterial photodynamic therapy	134:167	Antibacterial photodynamic therapy (APDT)	134:174	Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority.					
37067060	1	12	theme	Antibacterial	134:146	arg1	APDT					170:173	APDT	170:173	APDT	170:173	Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority.					
37067060	2	13	theme	photosensitizer	290:304	arg1	RB					319:320	RB	319:320	RB	319:320	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	13	theme	photosensitizer	290:304	arg1	Bengal					311:316	the photosensitizer Rose Bengal	286:316	the photosensitizer Rose Bengal (RB)	286:321	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	6	14	theme	inhibitory	1012:1021	arg1	effect					1023:1028	no significant inhibitory effect	997:1028	no significant inhibitory effect	997:1028	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	1	15	theme	considerable	189:200	arg1	attention					202:210	considerable attention	189:210	considerable attention	189:210	Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority.					
37067060	7	16	theme	food	1156:1159	arg1	packaging					1161:1169	food packaging	1156:1169	food packaging	1156:1169	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	6	17	contain	had	993:995	arg1	film					953:956	the composite film	939:956	the composite film	939:956	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	17	contain	had	993:995	arg2	effect					1023:1028	no significant inhibitory effect	997:1028	no significant inhibitory effect	997:1028	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	7	18	theme	antimicrobial	1128:1140	arg1	materials					1142:1150	novel APDT antimicrobial materials	1117:1150	novel APDT antimicrobial materials	1117:1150	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	4	19	theme	tensile	657:663	arg1	strength					665:672	The tensile strength	653:672	The tensile strength of the film	653:684	The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film.					
37067060	0	20	theme	UV-blocking	0:10	arg1	ε-caprolactone					39:52	ε-caprolactone	39:52	ε-caprolactone	39:52	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	0	20	theme	UV-blocking	0:10	arg1	poly					33:36	UV-blocking and light-responsive poly	0:36	UV-blocking and light-responsive poly (ε-caprolactone)	0:53	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	6	21	theme	RAW264.7	873:880	arg1	cells					882:886	RAW264.7 cells	873:886	RAW264.7 cells	873:886	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	22	contain	had	958:960	arg1	film					953:956	the composite film	939:956	the composite film	939:956	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	22	contain	had	958:960	arg2	biocompatibility					972:987	excellent biocompatibility	962:987	excellent biocompatibility	962:987	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	23	theme	significant	1000:1010	arg1	effect					1023:1028	no significant inhibitory effect	997:1028	no significant inhibitory effect	997:1028	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	7	24	theme	novel	1117:1121	arg1	materials					1142:1150	novel APDT antimicrobial materials	1117:1150	novel APDT antimicrobial materials	1117:1150	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	3	25	theme	excellent	573:581	arg1	sterilization					596:608	excellent photodynamic sterilization	573:608	excellent photodynamic sterilization	573:608	The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion.					
37067060	2	26	used	used	248:251	arg2	ZIF-8					238:242	ZIF-8	238:242	ZIF-8	238:242	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	5	27	theme	SiO2	786:789	arg1	addition					774:781	the addition	770:781	the addition of SiO2 and RB@ZIF-8 NPs	770:806	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	0	28	theme	light-responsive	16:31	arg1	ε-caprolactone					39:52	ε-caprolactone	39:52	ε-caprolactone	39:52	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	0	28	theme	light-responsive	16:31	arg1	poly					33:36	UV-blocking and light-responsive poly	0:36	UV-blocking and light-responsive poly (ε-caprolactone)	0:53	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	2	29	theme	composite	520:528	arg1	PQZ					537:539	PQZ	537:539	PQZ	537:539	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	29	theme	composite	520:528	arg1	films					530:534	composite films	520:534	composite films (PQZ)	520:540	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	5	30	dep	SiO2	786:789	arg1	NPs					804:806	@ZIF-8 NPs	797:806	@ZIF-8 NPs	797:806	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	2	31	theme	polyvinyl	441:449	arg1	chitosan					479:486	polyvinyl alcohol-quaternary ammonium chitosan	441:486	polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS)	441:496	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	31	theme	polyvinyl	441:449	arg1	PVA-QCS					489:495	PVA-QCS	489:495	PVA-QCS	489:495	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	32	theme	RB	351:352	arg1	NPs					360:362	RB@ZIF-8 NPs	351:362	RB@ZIF-8 NPs	351:362	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	32	theme	RB	351:352	arg1	substrates					501:510	substrates	501:510	substrates	501:510	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	3	33	theme	bacterial	633:641	arg1	adhesion					643:650	bacterial adhesion	633:650	bacterial adhesion	633:650	The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion.					
37067060	4	34	dep	times	737:741	arg1	that					743:746	that	743:746	that	743:746	The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film.					
37067060	5	35	theme	RB	795:796	arg1	addition					774:781	the addition	770:781	the addition of SiO2 and RB@ZIF-8 NPs	770:806	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	5	36	theme	ZIF-8	798:802	arg1	NPs					804:806	@ZIF-8 NPs	797:806	@ZIF-8 NPs	797:806	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	3	37	theme	good	614:617	arg1	resistance					619:628	good resistance	614:628	good resistance to bacterial adhesion	614:650	The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion.					
37067060	5	38	theme	UV-blocking	849:859	arg1	properties					861:870	UV-blocking properties	849:870	UV-blocking properties	849:870	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	2	39	theme	composite	389:397	arg1	film					399:402	a composite film	387:402	a composite film	387:402	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	6	40	theme	MTT	912:914	arg1	method					916:921	the MTT method	908:921	the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction	908:1060	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	2	41	theme	@	353:353	arg1	NPs					360:362	RB@ZIF-8 NPs	351:362	RB@ZIF-8 NPs	351:362	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	2	41	theme	@	353:353	arg1	substrates					501:510	substrates	501:510	substrates	501:510	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	3	42	theme	composite	547:555	arg1	films					557:561	The composite films	543:561	The composite films	543:561	The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion.					
37067060	1	43	theme	photodynamic	148:159	arg1	therapy					161:167	Antibacterial photodynamic therapy	134:167	Antibacterial photodynamic therapy (APDT)	134:174	Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority.					
37067060	1	43	theme	photodynamic	148:159	arg1	APDT					170:173	APDT	170:173	APDT	170:173	Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority.					
37067060	4	44	theme	film	759:762	arg1	times					737:741	approximately 1.8 times	719:741	approximately 1.8 times that of the PCL film	719:762	The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film.					
37067060	4	45	theme	PCL	755:757	arg1	film					759:762	the PCL film	751:762	the PCL film	751:762	The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film.					
37067060	6	46	dep	cell	1033:1036	arg1	reproduction					1049:1060	reproduction	1049:1060	reproduction	1049:1060	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	46	dep	cell	1033:1036	arg1	growth					1038:1043	growth	1038:1043	growth	1038:1043	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	6	47	theme	excellent	962:970	arg1	biocompatibility					972:987	excellent biocompatibility	962:987	excellent biocompatibility	962:987	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
37067060	0	48	theme	composite	78:86	arg1	films					88:92	multifunctional composite films	62:92	multifunctional composite films	62:92	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	5	49	theme	@	797:797	arg1	NPs					804:806	@ZIF-8 NPs	797:806	@ZIF-8 NPs	797:806	With the addition of SiO2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties.					
37067060	2	50	theme	poor	268:271	arg1	stability					273:281	the poor stability	264:281	the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ)	264:540	ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ε-caprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ).					
37067060	0	51	theme	multifunctional	62:76	arg1	films					88:92	multifunctional composite films	62:92	multifunctional composite films	62:92	UV-blocking and light-responsive poly (ε-caprolactone) /ZIF-8 multifunctional composite films for efficient antibacterial activities.					
37067060	3	52	theme	photodynamic	583:594	arg1	sterilization					596:608	excellent photodynamic sterilization	573:608	excellent photodynamic sterilization	573:608	The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion.					
37067060	7	53	theme	APDT	1123:1126	arg1	materials					1142:1150	novel APDT antimicrobial materials	1117:1150	novel APDT antimicrobial materials	1117:1150	PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.					
37067060	6	54	theme	composite	943:951	arg1	film					953:956	the composite film	939:956	the composite film	939:956	RAW264.7 cells were selected using the MTT method to confirm that the composite film had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction.					
36931482	0	0	theme	packaging	89:97	arg1	application					99:109	packaging application	89:109	packaging application	89:109	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	6	1	theme	scanning	1121:1128	arg1	SEM					1151:1153	SEM	1151:1153	SEM	1151:1153	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	6	1	theme	scanning	1121:1128	arg1	microscope					1139:1148	a scanning electron microscope	1119:1148	a scanning electron microscope (SEM)	1119:1154	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	3	2	theme	Introducing	396:406	arg1	frameworks					433:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	7	3	theme	mechanical	1288:1297	arg1	properties					1299:1308	mechanical properties	1288:1308	mechanical properties as well as degradation tests and real-time applications of the prepared films	1288:1386	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	3	4	theme	fabricating	589:599	arg1	materials					625:633	fabricating polymer-based packaging materials	589:633	fabricating polymer-based packaging materials	589:633	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	4	5	theme	Institute	662:670	arg1	Fe-					648:650	Fe-	648:650	Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract	648:794	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	5	theme	Institute	662:670	arg1	Lavoisier					672:680	Material Institute Lavoisier	653:680	Material Institute Lavoisier	653:680	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	5	6	theme	loaded	887:892	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	1	7	theme	possible	194:201	arg1	applications					203:214	their possible applications	188:214	their possible applications in food packaging	188:232	Bio-nanocomposite-based packaging materials have gained significance due to their possible applications in food packaging.					
36931482	7	8	theme	real-time	1343:1351	arg1	applications					1353:1364	real-time applications	1343:1364	real-time applications	1343:1364	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	7	9	theme	degradation	1321:1331	arg1	tests					1333:1337	degradation tests	1321:1337	degradation tests	1321:1337	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	5	10	theme	tensile	999:1005	arg1	strength					1007:1014	the tensile strength	995:1014	the tensile strength	995:1014	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	4	11	theme	prepared	813:820	arg1	material					822:829	the prepared material	809:829	the prepared material in different compositions and cast	809:864	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	3	12	theme	iron-based	408:417	arg1	frameworks					433:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	5	13	dep	loaded	887:892	arg1	Lavoisier					919:927	Material Institute Lavoisier	900:927	Material Institute Lavoisier	900:927	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	5	13	dep	loaded	887:892	arg1	Fe-					895:897	Fe-	895:897	Fe-	895:897	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	4	14	theme	cellulose	758:766	arg1	acetate					768:774	cellulose acetate	758:774	cellulose acetate	758:774	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	0	15	theme	cellulose	56:64	arg1	film					80:83	cellulose acetate based film	56:83	cellulose acetate based film	56:83	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	4	16	dep	Fe-	648:650	arg1	MIL-88A					683:689	MIL-88A	683:689	MIL-88A	683:689	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	16	dep	Fe-	648:650	arg1	framework					731:739	an iron-based nontoxic metal-organic framework	694:739	an iron-based nontoxic metal-organic framework	694:739	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	5	17	theme	acetate	959:965	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	4	18	theme	different	834:842	arg1	compositions					844:855	different compositions	834:855	different compositions	834:855	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	1	19	theme	food	219:222	arg1	packaging					224:232	food packaging	219:232	food packaging	219:232	Bio-nanocomposite-based packaging materials have gained significance due to their possible applications in food packaging.					
36931482	0	20	theme	Improved	0:7	arg1	performance					9:19	Improved performance	0:19	Improved performance of metal-organic frameworks	0:47	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	2	21	contain	has	310:312	arg1	biopolymer					258:267	a biopolymer	256:267	a biopolymer obtained by acetylation of cellulose	256:304	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	21	contain	has	310:312	arg2	transparency					382:393	high transparency	377:393	high transparency	377:393	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	21	contain	has	310:312	arg2	biocompatibility					338:353	biocompatibility	338:353	biocompatibility	338:353	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	21	contain	has	310:312	arg2	biodegradability					356:371	biodegradability	356:371	biodegradability	356:371	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	21	contain	has	310:312	arg1	acetate					245:251	Cellulose acetate	235:251	Cellulose acetate	235:251	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	21	contain	has	310:312	arg2	characteristics					314:328	characteristics	314:328	characteristics such as biocompatibility, biodegradability and high transparency	314:393	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	5	22	theme	cellulose	949:957	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	6	23	theme	thermogravimetric	1234:1250	arg1	TGA					1262:1264	TGA	1262:1264	TGA	1262:1264	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	6	23	theme	thermogravimetric	1234:1250	arg1	analysis					1252:1259	thermogravimetric analysis	1234:1259	thermogravimetric analysis (TGA)	1234:1265	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	3	24	theme	chemical	505:512	arg1	stability					528:536	both chemical and thermally stability	500:536	both chemical and thermally stability	500:536	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	0	25	theme	metal-organic	24:36	arg1	frameworks					38:47	metal-organic frameworks	24:47	metal-organic frameworks	24:47	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	6	26	theme	prepared	1077:1084	arg1	film					1086:1089	The prepared film	1073:1089	The prepared film	1073:1089	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	3	27	from	materials	576:584	arg1	materials					625:633	fabricating polymer-based packaging materials	589:633	fabricating polymer-based packaging materials	589:633	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	1	28	theme	Bio-nanocomposite-based	112:134	arg1	materials					146:154	Bio-nanocomposite-based packaging materials	112:154	Bio-nanocomposite-based packaging materials	112:154	Bio-nanocomposite-based packaging materials have gained significance due to their possible applications in food packaging.					
36931482	3	29	theme	mechanical	455:464	arg1	strength					466:473	good mechanical strength	450:473	good mechanical strength	450:473	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	4	30	theme	Material	653:660	arg1	Fe-					648:650	Fe-	648:650	Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract	648:794	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	30	theme	Material	653:660	arg1	Lavoisier					672:680	Material Institute Lavoisier	653:680	Material Institute Lavoisier	653:680	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	1	31	theme	packaging	136:144	arg1	materials					146:154	Bio-nanocomposite-based packaging materials	112:154	Bio-nanocomposite-based packaging materials	112:154	Bio-nanocomposite-based packaging materials have gained significance due to their possible applications in food packaging.					
36931482	4	32	theme	metal-organic	717:729	arg1	MIL-88A					683:689	MIL-88A	683:689	MIL-88A	683:689	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	32	theme	metal-organic	717:729	arg1	framework					731:739	an iron-based nontoxic metal-organic framework	694:739	an iron-based nontoxic metal-organic framework	694:739	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	7	33	theme	films	1382:1386	arg1	tests					1333:1337	degradation tests	1321:1337	degradation tests	1321:1337	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	7	33	theme	films	1382:1386	arg1	properties					1299:1308	mechanical properties	1288:1308	mechanical properties as well as degradation tests and real-time applications of the prepared films	1288:1386	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	7	33	theme	films	1382:1386	arg1	applications					1353:1364	real-time applications	1343:1364	real-time applications	1343:1364	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	7	34	theme	prepared	1373:1380	arg1	films					1382:1386	the prepared films	1369:1386	the prepared films	1369:1386	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	5	35	theme	MIL-88A	930:936	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	0	36	theme	frameworks	38:47	arg1	performance					9:19	Improved performance	0:19	Improved performance of metal-organic frameworks	0:47	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	5	37	theme	Spinach	879:885	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	7	38	from	studies	1277:1283	arg1	tests					1333:1337	degradation tests	1321:1337	degradation tests	1321:1337	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	7	38	from	studies	1277:1283	arg1	properties					1299:1308	mechanical properties	1288:1308	mechanical properties as well as degradation tests and real-time applications of the prepared films	1288:1386	Further, studies on mechanical properties as well as degradation tests and real-time applications of the prepared films were carried out.					
36931482	3	39	theme	good	450:453	arg1	strength					466:473	good mechanical strength	450:473	good mechanical strength	450:473	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	3	40	theme	metal-organic	419:431	arg1	frameworks					433:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks	396:442	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	3	41	theme	unique	476:481	arg1	area					491:494	unique surface area	476:494	unique surface area	476:494	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	0	42	theme	based	74:78	arg1	film					80:83	cellulose acetate based film	56:83	cellulose acetate based film	56:83	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	3	43	theme	surface	483:489	arg1	area					491:494	unique surface area	476:494	unique surface area	476:494	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	5	44	theme	Material	900:907	arg1	Lavoisier					919:927	Material Institute Lavoisier	900:927	Material Institute Lavoisier	900:927	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	5	45	theme	water	1017:1021	arg1	permeability					1030:1041	water vapour permeability	1017:1041	water vapour permeability	1017:1041	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	4	46	from	material	822:829	arg1	compositions					844:855	different compositions	834:855	different compositions	834:855	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	46	from	material	822:829	arg1	cast					861:864	cast	861:864	cast	861:864	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	47	theme	spinach	780:786	arg1	extract					788:794	spinach extract	780:794	spinach extract	780:794	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	5	48	theme	vapour	1023:1028	arg1	permeability					1030:1041	water vapour permeability	1017:1041	water vapour permeability	1017:1041	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	5	49	theme	anti-microbial	1048:1061	arg1	activity					1063:1070	anti-microbial activity	1048:1070	anti-microbial activity	1048:1070	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	6	50	theme	X-ray	1206:1210	arg1	diffraction					1212:1222	X-ray diffraction	1206:1222	X-ray diffraction (XRD)	1206:1228	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	6	50	theme	X-ray	1206:1210	arg1	XRD					1225:1227	XRD	1225:1227	XRD	1225:1227	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	2	51	theme	Cellulose	235:243	arg1	acetate					245:251	Cellulose acetate	235:251	Cellulose acetate	235:251	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	51	theme	Cellulose	235:243	arg1	biopolymer					258:267	a biopolymer	256:267	a biopolymer obtained by acetylation of cellulose	256:304	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	52	theme	cellulose	296:304	arg1	acetylation					281:291	acetylation	281:291	acetylation of cellulose	281:304	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	2	53	theme	high	377:380	arg1	transparency					382:393	high transparency	377:393	high transparency	377:393	Cellulose acetate is a biopolymer obtained by acetylation of cellulose and has characteristics such as biocompatibility, biodegradability and high transparency.					
36931482	6	54	theme	electron	1130:1137	arg1	SEM					1151:1153	SEM	1151:1153	SEM	1151:1153	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	6	54	theme	electron	1130:1137	arg1	microscope					1139:1148	a scanning electron microscope	1119:1148	a scanning electron microscope (SEM)	1119:1154	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	5	55	theme	integrated	938:947	arg1	film					967:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film	875:970	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	3	56	theme	polymer-based	601:613	arg1	materials					625:633	fabricating polymer-based packaging materials	589:633	fabricating polymer-based packaging materials	589:633	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	6	57	theme	infrared	1176:1183	arg1	FTIR					1199:1202	FTIR	1199:1202	FTIR	1199:1202	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	6	57	theme	infrared	1176:1183	arg1	spectrometer					1185:1196	infrared spectrometer	1176:1196	infrared spectrometer (FTIR)	1176:1203	The prepared film is then characterized using a scanning electron microscope (SEM), Fourier transforms infrared spectrometer (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA).					
36931482	4	58	theme	nontoxic	708:715	arg1	MIL-88A					683:689	MIL-88A	683:689	MIL-88A	683:689	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	58	theme	nontoxic	708:715	arg1	framework					731:739	an iron-based nontoxic metal-organic framework	694:739	an iron-based nontoxic metal-organic framework	694:739	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	0	59	theme	acetate	66:72	arg1	film					80:83	cellulose acetate based film	56:83	cellulose acetate based film	56:83	Improved performance of metal-organic frameworks loaded cellulose acetate based film for packaging application.					
36931482	5	60	theme	Institute	909:917	arg1	Lavoisier					919:927	Material Institute Lavoisier	900:927	Material Institute Lavoisier	900:927	The Spinach loaded, Fe- (Material Institute Lavoisier) MIL-88A integrated cellulose acetate film significantly enhanced the tensile strength, water vapour permeability, and anti-microbial activity.					
36931482	1	61	from	applications	203:214	arg1	packaging					224:232	food packaging	219:232	food packaging	219:232	Bio-nanocomposite-based packaging materials have gained significance due to their possible applications in food packaging.					
36931482	3	62	theme	packaging	615:623	arg1	materials					625:633	fabricating polymer-based packaging materials	589:633	fabricating polymer-based packaging materials	589:633	Introducing iron-based metal-organic frameworks offer good mechanical strength, unique surface area and both chemical and thermally stability, making them favourable as supporting materials in fabricating polymer-based packaging materials.					
36931482	4	63	theme	iron-based	697:706	arg1	MIL-88A					683:689	MIL-88A	683:689	MIL-88A	683:689	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36931482	4	63	theme	iron-based	697:706	arg1	framework					731:739	an iron-based nontoxic metal-organic framework	694:739	an iron-based nontoxic metal-organic framework	694:739	Among them, Fe- (Material Institute Lavoisier) MIL-88A is an iron-based nontoxic metal-organic framework, integrated with cellulose acetate and spinach extract was added to the prepared material in different compositions and cast as film.					
36455281	10	0	theme	adhesive	1658:1665	arg1	applications					1667:1678	suit different adhesive applications	1643:1678	suit different adhesive applications using casein	1643:1691	These interactions at multiple scales can be tuned to suit different adhesive applications using casein.					
36455281	5	1	theme	shear	570:574	arg1	strength					576:583	The lap shear strength	562:583	The lap shear strength of casein bonded cellulose pressboards	562:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	10	2	theme	different	1648:1656	arg1	applications					1667:1678	suit different adhesive applications	1643:1678	suit different adhesive applications using casein	1643:1691	These interactions at multiple scales can be tuned to suit different adhesive applications using casein.					
36455281	9	3	theme	conformational	1410:1423	arg1	changes					1425:1431	conformational changes	1410:1431	conformational changes in the protein structure of casein during drying	1410:1480	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	6	4	dep	Fourier	709:715	arg1	transform					717:725	transform	717:725	transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions	717:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	6	5	theme	casein	919:924	arg1	dispersions					926:936	casein dispersions	919:936	casein dispersions	919:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	9	6	theme	microporous	1261:1271	arg1	substrate					1283:1291	microporous cellulose substrate	1261:1291	microporous cellulose substrate	1261:1291	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	3	7	theme	changes	384:390	arg1	contributions					361:373	the multiscale contributions	346:373	the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards	346:441	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	9	8	from	microstructure	1483:1496	arg1	dispersion					1525:1534	the dispersion	1521:1534	the dispersion	1521:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	8	from	microstructure	1483:1496	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	6	9	theme	α-helical	856:864	arg1	conformations					866:878	more α-helical conformations	851:878	more α-helical conformations	851:878	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	2	10	theme	interfacial	292:302	arg1	bonding					304:310	interfacial bonding	292:310	interfacial bonding	292:310	Casein being a protein can undergo conformational and microstructural changes during various processing steps involved in interfacial bonding.					
36455281	6	11	theme	spectroscopy	736:747	arg1	investigations					756:769	spectroscopy (FTIR) investigations	736:769	spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions	736:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	4	12	theme	adhesion	508:515	arg1	characteristics					517:531	macroscopic adhesion characteristics	496:531	macroscopic adhesion characteristics	496:531	Investigations spanning from molecular structure to macroscopic adhesion characteristics have been used in this work.					
36455281	6	13	dep	transform	717:725	arg1	infrared					727:734	infrared	727:734	transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions	717:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	9	14	theme	cellulose	1273:1281	arg1	substrate					1283:1291	microporous cellulose substrate	1261:1291	microporous cellulose substrate	1261:1291	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	15	theme	microporous	1545:1555	arg1	nature					1557:1562	the microporous nature	1541:1562	the microporous nature of the cellulose boards	1541:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	0	16	from	Interactions	45:56	arg1	Adhesion					78:85	Cellulose-Casein Adhesion	61:85	Cellulose-Casein Adhesion	61:85	Multiscale Approach to Studying Biomolecular Interactions in Cellulose-Casein Adhesion.					
36455281	5	17	theme	cellulose	602:610	arg1	pressboards					612:622	casein bonded cellulose pressboards	588:622	casein bonded cellulose pressboards	588:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	9	18	theme	polar-polar	1350:1360	arg1	interactions					1362:1373	the polar-polar interactions	1346:1373	the polar-polar interactions of casein and cellulose molecules	1346:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	5	19	theme	casein	666:671	arg1	concentration					673:685	casein concentration	666:685	casein concentration	666:685	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	5	20	theme	pressboards	612:622	arg1	strength					576:583	The lap shear strength	562:583	The lap shear strength of casein bonded cellulose pressboards	562:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	3	21	from	casein	395:400	arg1	contributions					361:373	the multiscale contributions	346:373	the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards	346:441	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	0	22	theme	Multiscale	0:9	arg1	Approach					11:18	Multiscale Approach	0:18	Multiscale Approach	0:18	Multiscale Approach to Studying Biomolecular Interactions in Cellulose-Casein Adhesion.					
36455281	8	23	theme	bonding	1157:1163	arg1	strength					1165:1172	the bonding strength	1153:1172	the bonding strength of casein with cellulose	1153:1197	Casein compositions lacking α-helices were found to enhance the bonding strength of casein with cellulose.					
36455281	8	24	with	strength	1165:1172	arg1	cellulose					1189:1197	cellulose	1189:1197	cellulose	1189:1197	Casein compositions lacking α-helices were found to enhance the bonding strength of casein with cellulose.					
36455281	9	25	theme	cellulose	1571:1579	arg1	boards					1581:1586	the cellulose boards	1567:1586	the cellulose boards	1567:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	4	26	used	used	543:546	arg2	Investigations					444:457	Investigations	444:457	Investigations spanning from molecular structure to macroscopic adhesion characteristics	444:531	Investigations spanning from molecular structure to macroscopic adhesion characteristics have been used in this work.					
36455281	9	27	theme	casein	1461:1466	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	8	28	theme	casein	1177:1182	arg1	strength					1165:1172	the bonding strength	1153:1172	the bonding strength of casein with cellulose	1153:1197	Casein compositions lacking α-helices were found to enhance the bonding strength of casein with cellulose.					
36455281	6	29	theme	casein	822:827	arg1	dispersions					829:839	casein dispersions	822:839	casein dispersions	822:839	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	7	30	theme	wetting	1042:1048	arg1	characteristics					1050:1064	the wetting characteristics	1038:1064	the wetting characteristics	1038:1064	This results in increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior.					
36455281	9	31	theme	boards	1581:1586	arg1	changes					1425:1431	conformational changes	1410:1431	conformational changes in the protein structure of casein during drying	1410:1480	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	31	theme	boards	1581:1586	arg1	microstructure					1483:1496	microstructure	1483:1496	microstructure of casein particles in the dispersion	1483:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	31	theme	boards	1581:1586	arg1	nature					1557:1562	the microporous nature	1541:1562	the microporous nature of the cellulose boards	1541:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	31	theme	boards	1581:1586	arg1	contributions					1297:1309	contributions	1297:1309	contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules	1297:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	5	32	from	increase	654:661	arg1	concentration					673:685	casein concentration	666:685	casein concentration	666:685	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	6	33	theme	rheological	797:807	arg1	studies					809:815	rheological studies	797:815	rheological studies	797:815	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	3	34	from	contributions	361:373	arg1	casein					395:400	casein	395:400	casein	395:400	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	9	35	theme	present	1204:1210	arg1	study					1212:1216	The present study	1200:1216	The present study	1200:1216	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	36	from	nature	1557:1562	arg1	dispersion					1525:1534	the dispersion	1521:1534	the dispersion	1521:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	36	from	nature	1557:1562	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	3	37	theme	cellulose	421:429	arg1	pressboards					431:441	cellulose pressboards	421:441	cellulose pressboards	421:441	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	10	38	theme	multiple	1611:1618	arg1	scales					1620:1625	multiple scales	1611:1625	multiple scales	1611:1625	These interactions at multiple scales can be tuned to suit different adhesive applications using casein.					
36455281	4	39	theme	molecular	473:481	arg1	structure					483:491	molecular structure	473:491	molecular structure	473:491	Investigations spanning from molecular structure to macroscopic adhesion characteristics have been used in this work.					
36455281	0	40	theme	Biomolecular	32:43	arg1	Interactions					45:56	Biomolecular Interactions	32:56	Biomolecular Interactions in Cellulose-Casein Adhesion	32:85	Multiscale Approach to Studying Biomolecular Interactions in Cellulose-Casein Adhesion.					
36455281	9	41	from	changes	1425:1431	arg1	dispersion					1525:1534	the dispersion	1521:1534	the dispersion	1521:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	41	from	changes	1425:1431	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	4	42	theme	macroscopic	496:506	arg1	characteristics					517:531	macroscopic adhesion characteristics	496:531	macroscopic adhesion characteristics	496:531	Investigations spanning from molecular structure to macroscopic adhesion characteristics have been used in this work.					
36455281	2	43	theme	microstructural	224:238	arg1	changes					240:246	conformational and microstructural changes	205:246	conformational and microstructural changes	205:246	Casein being a protein can undergo conformational and microstructural changes during various processing steps involved in interfacial bonding.					
36455281	0	44	theme	Cellulose-Casein	61:76	arg1	Adhesion					78:85	Cellulose-Casein Adhesion	61:85	Cellulose-Casein Adhesion	61:85	Multiscale Approach to Studying Biomolecular Interactions in Cellulose-Casein Adhesion.					
36455281	10	45	theme	suit	1643:1646	arg1	applications					1667:1678	suit different adhesive applications	1643:1678	suit different adhesive applications using casein	1643:1691	These interactions at multiple scales can be tuned to suit different adhesive applications using casein.					
36455281	3	46	from	changes	384:390	arg1	casein					395:400	casein	395:400	casein	395:400	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	9	47	theme	protein	1440:1446	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	1	48	theme	adhesive	132:139	arg1	application					101:111	application	101:111	application	101:111	Casein finds application as an eco-friendly adhesive for paper, wood, glass, etc.					
36455281	1	48	theme	adhesive	132:139	arg1	eco-friendly					119:130	an eco-friendly	116:130	an eco-friendly adhesive for paper, wood, glass, etc	116:167	Casein finds application as an eco-friendly adhesive for paper, wood, glass, etc.					
36455281	2	49	theme	conformational	205:218	arg1	changes					240:246	conformational and microstructural changes	205:246	conformational and microstructural changes	205:246	Casein being a protein can undergo conformational and microstructural changes during various processing steps involved in interfacial bonding.					
36455281	5	50	theme	casein	588:593	arg1	pressboards					612:622	casein bonded cellulose pressboards	588:622	casein bonded cellulose pressboards	588:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	6	51	theme	dispersions	926:936	arg1	process					908:914	the preconcentration process	887:914	the preconcentration process of casein dispersions	887:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	7	52	theme	casein	987:992	arg1	particles/aggregates					994:1013	the casein particles/aggregates	983:1013	the casein particles/aggregates	983:1013	This results in increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior.					
36455281	9	53	theme	casein	1501:1506	arg1	particles					1508:1516	casein particles	1501:1516	casein particles	1501:1516	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	54	from	multiscale	1318:1327	arg1	changes					1425:1431	conformational changes	1410:1431	conformational changes in the protein structure of casein during drying	1410:1480	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	54	from	multiscale	1318:1327	arg1	microstructure					1483:1496	microstructure	1483:1496	microstructure of casein particles in the dispersion	1483:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	54	from	multiscale	1318:1327	arg1	nature					1557:1562	the microporous nature	1541:1562	the microporous nature of the cellulose boards	1541:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	54	from	multiscale	1318:1327	arg1	contributions					1297:1309	contributions	1297:1309	contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules	1297:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	8	55	theme	Casein	1093:1098	arg1	compositions					1100:1111	Casein compositions	1093:1111	Casein compositions lacking α-helices	1093:1129	Casein compositions lacking α-helices were found to enhance the bonding strength of casein with cellulose.					
36455281	5	56	theme	bonded	595:600	arg1	pressboards					612:622	casein bonded cellulose pressboards	588:622	casein bonded cellulose pressboards	588:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	7	57	theme	particles/aggregates	994:1013	arg1	hydrophobicity					965:978	increased hydrophobicity	955:978	increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior	955:1090	This results in increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior.					
36455281	9	58	theme	particles	1508:1516	arg1	changes					1425:1431	conformational changes	1410:1431	conformational changes in the protein structure of casein during drying	1410:1480	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	58	theme	particles	1508:1516	arg1	microstructure					1483:1496	microstructure	1483:1496	microstructure of casein particles in the dispersion	1483:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	58	theme	particles	1508:1516	arg1	nature					1557:1562	the microporous nature	1541:1562	the microporous nature of the cellulose boards	1541:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	58	theme	particles	1508:1516	arg1	contributions					1297:1309	contributions	1297:1309	contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules	1297:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	6	59	theme	preconcentration	891:906	arg1	process					908:914	the preconcentration process	887:914	the preconcentration process of casein dispersions	887:936	It was observed from Fourier transform infrared spectroscopy (FTIR) investigations along with microscopy and rheological studies that casein dispersions result in more α-helical conformations during the preconcentration process of casein dispersions.					
36455281	2	60	theme	processing	263:272	arg1	steps					274:278	various processing steps	255:278	various processing steps involved in interfacial bonding	255:310	Casein being a protein can undergo conformational and microstructural changes during various processing steps involved in interfacial bonding.					
36455281	7	61	theme	adhesion	1074:1081	arg1	behavior					1083:1090	the adhesion behavior	1070:1090	the adhesion behavior	1070:1090	This results in increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior.					
36455281	9	62	contain	has	1293:1295	arg2	changes					1425:1431	conformational changes	1410:1431	conformational changes in the protein structure of casein during drying	1410:1480	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	62	contain	has	1293:1295	arg2	nature					1557:1562	the microporous nature	1541:1562	the microporous nature of the cellulose boards	1541:1586	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	62	contain	has	1293:1295	arg2	microstructure					1483:1496	microstructure	1483:1496	microstructure of casein particles in the dispersion	1483:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	62	contain	has	1293:1295	arg1	adhesion					1233:1240	the adhesion	1229:1240	the adhesion between casein and microporous cellulose substrate	1229:1291	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	62	contain	has	1293:1295	arg2	contributions					1297:1309	contributions	1297:1309	contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules	1297:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	63	theme	cellulose	1389:1397	arg1	molecules					1399:1407	casein and cellulose molecules	1378:1407	casein and cellulose molecules	1378:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	2	64	theme	various	255:261	arg1	steps					274:278	various processing steps	255:278	various processing steps involved in interfacial bonding	255:310	Casein being a protein can undergo conformational and microstructural changes during various processing steps involved in interfacial bonding.					
36455281	9	65	theme	casein	1378:1383	arg1	molecules					1399:1407	casein and cellulose molecules	1378:1407	casein and cellulose molecules	1378:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	3	66	theme	multiscale	350:359	arg1	contributions					361:373	the multiscale contributions	346:373	the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards	346:441	This study aims at understanding the multiscale contributions of these changes in casein to its adhesion to cellulose pressboards.					
36455281	9	67	theme	molecules	1399:1407	arg1	interactions					1362:1373	the polar-polar interactions	1346:1373	the polar-polar interactions of casein and cellulose molecules	1346:1407	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	5	68	theme	lap	566:568	arg1	strength					576:583	The lap shear strength	562:583	The lap shear strength of casein bonded cellulose pressboards	562:622	The lap shear strength of casein bonded cellulose pressboards is found to increase with the increase in casein concentration.					
36455281	9	69	from	contributions	1297:1309	arg1	dispersion					1525:1534	the dispersion	1521:1534	the dispersion	1521:1534	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	9	69	from	contributions	1297:1309	arg1	structure					1448:1456	the protein structure	1436:1456	the protein structure of casein	1436:1466	The present study shows that the adhesion between casein and microporous cellulose substrate has contributions at the multiscale originating from the polar-polar interactions of casein and cellulose molecules, conformational changes in the protein structure of casein during drying, microstructure of casein particles in the dispersion, and the microporous nature of the cellulose boards.					
36455281	7	70	theme	increased	955:963	arg1	hydrophobicity					965:978	increased hydrophobicity	955:978	increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior	955:1090	This results in increased hydrophobicity of the casein particles/aggregates, which in turn affects the wetting characteristics and the adhesion behavior.					
36455281	10	71	from	scales	1620:1625	arg1	interactions					1595:1606	These interactions	1589:1606	These interactions at multiple scales	1589:1625	These interactions at multiple scales can be tuned to suit different adhesive applications using casein.					
36876803	0	0	theme	bone	109:112	arg1	repair					114:119	bone repair	109:119	bone repair	109:119	Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair.					
36876803	6	1	theme	osteogenic	925:934	arg1	differentiation					936:950	MC3T3-E1 osteogenic differentiation	916:950	MC3T3-E1 osteogenic differentiation	916:950	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	7	2	theme	rich	1016:1019	arg1	microspheres					1003:1014	microspheres	1003:1014	microspheres rich in chondroitin sulfate	1003:1042	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	2	3	theme	composite	367:375	arg1	scaffolds					377:385	composite scaffolds	367:385	composite scaffolds for bone repair	367:401	Here, microspheres were covalently integrated into 3D-printed frameworks to form composite scaffolds for bone repair.					
36876803	6	4	theme	MC3T3-E1	916:923	arg1	differentiation					936:950	MC3T3-E1 osteogenic differentiation	916:950	MC3T3-E1 osteogenic differentiation	916:950	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	7	5	theme	bone	1136:1139	arg1	repair					1141:1146	enhanced bone repair	1127:1146	enhanced bone repair	1127:1146	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	3	6	theme	strong	509:514	arg1	support					516:522	strong support	509:522	strong support for related cells climbing and growth	509:560	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	1	7	theme	repair	132:137	arg1	structure					177:185	multi-connected channel structure	153:185	multi-connected channel structure	153:185	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	7	theme	repair	132:137	arg1	scaffolds					139:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	7	8	theme	bridging	984:991	arg1	effect					993:998	the bridging effect	980:998	the bridging effect of microspheres rich in chondroitin sulfate	980:1042	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	6	9	theme	skull	891:895	arg1	defect					897:902	repair mouse skull defect	878:902	repair mouse skull defect	878:902	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	7	10	theme	enhanced	1127:1134	arg1	repair					1141:1146	enhanced bone repair	1127:1146	enhanced bone repair	1127:1146	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	5	11	theme	osteoblasts	797:807	arg1	migration					784:792	the migration	780:792	the migration of osteoblasts	780:807	Additionally, CSA released from microspheres promoted the migration of osteoblasts and enhanced osteogenesis.					
36876803	1	12	theme	hollow	196:201	arg1	structure					203:211	the hollow structure	192:211	the hollow structure	192:211	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	12	theme	hollow	196:201	arg1	conducive					220:228	conducive	220:228	conducive	220:228	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	6	13	theme	mouse	885:889	arg1	defect					897:902	repair mouse skull defect	878:902	repair mouse skull defect	878:902	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	7	14	theme	promising	1103:1111	arg1	candidate					1113:1121	a promising candidate	1101:1121	a promising candidate for enhanced bone repair	1101:1146	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	0	15	theme	Biocompatible	0:12	arg1	scaffolds					14:22	Biocompatible scaffolds	0:22	Biocompatible scaffolds	0:22	Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair.					
36876803	1	16	theme	on	282:283	arg1	transmission					237:248	the transmission	233:248	the transmission of active factors, cells and so on	233:283	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	4	17	theme	cells	709:713	arg1	migration					715:723	cells migration	709:723	cells migration	709:723	Microspheres, which were made of Gel-MA and chondroitin sulfate A (CSA), were able to connect the frameworks like bridges, providing channels for cells migration.					
36876803	2	18	theme	bone	391:394	arg1	repair					396:401	bone repair	391:401	bone repair	391:401	Here, microspheres were covalently integrated into 3D-printed frameworks to form composite scaffolds for bone repair.					
36876803	1	19	theme	Most	122:125	arg1	structure					177:185	multi-connected channel structure	153:185	multi-connected channel structure	153:185	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	19	theme	Most	122:125	arg1	scaffolds					139:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	7	20	from	sulfate	1036:1042	arg1	rich					1016:1019	rich	1016:1019	rich	1016:1019	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	6	21	theme	composite	840:848	arg1	scaffolds					850:858	The composite scaffolds	836:858	The composite scaffolds	836:858	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	6	22	theme	repair	878:883	arg1	defect					897:902	repair mouse skull defect	878:902	repair mouse skull defect	878:902	The composite scaffolds could effectively repair mouse skull defect and improve MC3T3-E1 osteogenic differentiation.					
36876803	1	23	theme	bone	127:130	arg1	structure					177:185	multi-connected channel structure	153:185	multi-connected channel structure	153:185	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	23	theme	bone	127:130	arg1	scaffolds					139:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	0	24	theme	sulfate	51:57	arg1	microspheres					59:70	chondroitin sulfate microspheres	39:70	chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair	39:119	Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair.					
36876803	3	25	theme	double	431:436	arg1	bond					438:441	double bond	431:441	double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP)	431:498	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	0	26	theme	chondroitin	39:49	arg1	microspheres					59:70	chondroitin sulfate microspheres	39:70	chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair	39:119	Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair.					
36876803	7	27	theme	composite	1072:1080	arg1	scaffold					1082:1089	the composite scaffold	1068:1089	the composite scaffold	1068:1089	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	3	28	dep	cells	536:540	arg1	cells					536:540	related cells climbing and growth	528:560	related cells climbing and growth	528:560	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	3	28	dep	cells	536:540	arg1	growth					555:560	growth	555:560	growth	555:560	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	3	28	dep	cells	536:540	arg1	climbing					542:549	climbing	542:549	climbing	542:549	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	1	29	dep	and	275:277	arg1	so					279:280	so	279:280	so	279:280	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	5	30	attach	released	744:751	arg2	CSA					740:742	CSA	740:742	CSA released from microspheres	740:769	Additionally, CSA released from microspheres promoted the migration of osteoblasts and enhanced osteogenesis.					
36876803	5	30	attach	released	744:751	arg1	microspheres					758:769	microspheres	758:769	microspheres	758:769	Additionally, CSA released from microspheres promoted the migration of osteoblasts and enhanced osteogenesis.					
36876803	2	31	theme	3D-printed	337:346	arg1	frameworks					348:357	3D-printed frameworks	337:357	3D-printed frameworks	337:357	Here, microspheres were covalently integrated into 3D-printed frameworks to form composite scaffolds for bone repair.					
36876803	4	32	theme	chondroitin	607:617	arg1	CSA					630:632	CSA	630:632	CSA	630:632	Microspheres, which were made of Gel-MA and chondroitin sulfate A (CSA), were able to connect the frameworks like bridges, providing channels for cells migration.					
36876803	4	32	theme	chondroitin	607:617	arg1	A					627:627	chondroitin sulfate A	607:627	chondroitin sulfate A (CSA)	607:633	Microspheres, which were made of Gel-MA and chondroitin sulfate A (CSA), were able to connect the frameworks like bridges, providing channels for cells migration.					
36876803	1	33	theme	multi-connected	153:167	arg1	structure					177:185	multi-connected channel structure	153:185	multi-connected channel structure	153:185	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	33	theme	multi-connected	153:167	arg1	scaffolds					139:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	7	34	theme	chondroitin	1024:1034	arg1	sulfate					1036:1042	chondroitin sulfate	1024:1042	chondroitin sulfate	1024:1042	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	1	35	theme	channel	169:175	arg1	structure					177:185	multi-connected channel structure	153:185	multi-connected channel structure	153:185	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	35	theme	channel	169:175	arg1	scaffolds					139:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds	122:147	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	7	36	from	rich	1016:1019	arg1	sulfate					1036:1042	chondroitin sulfate	1024:1042	chondroitin sulfate	1024:1042	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	1	37	theme	active	253:258	arg1	cells					269:273	cells	269:273	cells	269:273	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	1	37	theme	active	253:258	arg1	factors					260:266	active factors	253:266	active factors	253:266	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
36876803	0	38	theme	3D-printed	83:92	arg1	frameworks					94:103	3D-printed frameworks	83:103	3D-printed frameworks for bone repair	83:119	Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair.					
36876803	4	39	theme	sulfate	619:625	arg1	CSA					630:632	CSA	630:632	CSA	630:632	Microspheres, which were made of Gel-MA and chondroitin sulfate A (CSA), were able to connect the frameworks like bridges, providing channels for cells migration.					
36876803	4	39	theme	sulfate	619:625	arg1	A					627:627	chondroitin sulfate A	607:627	chondroitin sulfate A (CSA)	607:633	Microspheres, which were made of Gel-MA and chondroitin sulfate A (CSA), were able to connect the frameworks like bridges, providing channels for cells migration.					
36876803	7	40	theme	microspheres	1003:1014	arg1	effect					993:998	the bridging effect	980:998	the bridging effect of microspheres rich in chondroitin sulfate	980:1042	These observations confirm the bridging effect of microspheres rich in chondroitin sulfate and also determine that the composite scaffold can be as a promising candidate for enhanced bone repair.					
36876803	3	41	theme	related	528:534	arg1	cells					536:540	related cells climbing and growth	528:560	related cells climbing and growth	528:560	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	3	41	theme	related	528:534	arg1	growth					555:560	growth	555:560	growth	555:560	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	3	41	theme	related	528:534	arg1	climbing					542:549	climbing	542:549	climbing	542:549	The frameworks composed of double bond modified gelatin (Gel-MA) and nano-hydroxyapatite (nHAP) provided strong support for related cells climbing and growth.					
36876803	1	42	theme	factors	260:266	arg1	transmission					237:248	the transmission	233:248	the transmission of active factors, cells and so on	233:283	Most bone repair scaffolds are multi-connected channel structure, but the hollow structure is not conducive to the transmission of active factors, cells and so on.					
35949096	0	0	theme	blue	96:99	arg1	sequestration					101:113	methylene blue sequestration	86:113	methylene blue sequestration from aqueous medium	86:133	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	5	1	theme	equilibrium	1032:1042	arg1	data					1044:1047	the equilibrium data	1028:1047	the equilibrium data	1028:1047	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	1	2	theme	pozzolan-based	156:169	arg1	GP5					188:190	GP5	188:190	GP5	188:190	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	2	theme	pozzolan-based	156:169	arg1	GP0					183:185	GP0	183:185	GP0	183:185	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	2	theme	pozzolan-based	156:169	arg1	GP20					203:206	GP20	203:206	GP20	203:206	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	2	theme	pozzolan-based	156:169	arg1	GP10					193:196	GP10	193:196	GP10	193:196	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	2	theme	pozzolan-based	156:169	arg1	geopolymers					171:181	four pozzolan-based geopolymers	151:181	four pozzolan-based geopolymers GP0, GP5, GP10, and GP20	151:206	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	8	3	theme	cheaper	1398:1404	arg1	eco-adsorbents					1406:1419	efficient and cheaper eco-adsorbents	1384:1419	efficient and cheaper eco-adsorbents than commercial activated carbon	1384:1452	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	8	3	theme	cheaper	1398:1404	arg1	composites					1369:1378	the composites	1365:1378	the composites	1365:1378	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	8	4	theme	commercial	1426:1435	arg1	carbon					1447:1452	commercial activated carbon	1426:1452	commercial activated carbon	1426:1452	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	1	5	theme	precursor	293:301	arg1	%					284:284	0, 5, 10, and 20%	268:284	0, 5, 10, and 20% of the precursor	268:301	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	5	theme	precursor	293:301	arg1	precursor					293:301	the precursor	289:301	the precursor	289:301	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	3	6	theme	-biochar	781:788	arg1	chains					790:795	poly (Ferro-sialate-siloxo)-biochar chains	754:795	poly (Ferro-sialate-siloxo)-biochar chains	754:795	The alkaline activation of pozzolan-biochar blends resulted in the formation of poly (Ferro-sialate-siloxo)-biochar chains.					
35949096	2	7	theme	infrared	463:470	arg1	FTIR					486:489	FTIR	486:489	FTIR	486:489	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	7	theme	infrared	463:470	arg1	spectroscopy					472:483	infrared spectroscopy	463:483	infrared spectroscopy (FTIR)	463:490	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	6	8	dep	endothermic	1155:1165	arg1	ΔH = 14.32-32.20 kJ/mol					1168:1190	ΔH = 14.32-32.20 kJ/mol	1168:1190	ΔH = 14.32-32.20 kJ/mol	1168:1190	The adsorption process was thermodynamically spontaneous, endothermic (ΔH = 14.32-32.20 kJ/mol), and physical.					
35949096	1	9	link	bagasse-derived	318:332	arg1	biochar					334:340	sugarcane bagasse-derived biochar	308:340	sugarcane bagasse-derived biochar	308:340	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	10	theme	sugarcane	308:316	arg1	biochar					334:340	sugarcane bagasse-derived biochar	308:340	sugarcane bagasse-derived biochar	308:340	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	2	11	dep	fluorescence	400:411	arg1	analyses					579:586	analyses	579:586	analyses	579:586	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	12	theme	surface	566:572	arg1	area					574:577	Brunauer-Emmett-Teller (BET) surface area	537:577	Brunauer-Emmett-Teller (BET) surface area	537:577	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	7	13	theme	effluent	1312:1319	arg1	volumes					1301:1307	different volumes	1291:1307	different volumes of effluent	1291:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	0	14	theme	aqueous	120:126	arg1	medium					128:133	aqueous medium	120:133	aqueous medium	120:133	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	1	15	theme	bagasse-derived	318:332	arg1	biochar					334:340	sugarcane bagasse-derived biochar	308:340	sugarcane bagasse-derived biochar	308:340	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	2	16	theme	BET	561:563	arg1	area					574:577	Brunauer-Emmett-Teller (BET) surface area	537:577	Brunauer-Emmett-Teller (BET) surface area	537:577	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	5	17	theme	pseudo-second-order	993:1011	arg1	kinetics					1013:1020	pseudo-second-order kinetics	993:1020	pseudo-second-order kinetics	993:1020	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	8	18	from	removal	1502:1508	arg1	water					1523:1527	water	1523:1527	water	1523:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	8	19	theme	alternative	1471:1481	arg1	candidates					1483:1492	suitable alternative candidates	1462:1492	suitable alternative candidates for the removal of dyes from water	1462:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	2	20	theme	aqueous	644:650	arg1	medium					652:657	an aqueous medium	641:657	an aqueous medium	641:657	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	8	21	from	water	1523:1527	arg1	removal					1502:1508	the removal	1498:1508	the removal of dyes from water	1498:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	8	21	from	water	1523:1527	arg1	dyes					1513:1516	dyes	1513:1516	dyes from water	1513:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	5	22	theme	Sips	1076:1079	arg1	model					1090:1094	the Sips isotherm model	1072:1094	the Sips isotherm model	1072:1094	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	2	23	theme	Brunauer-Emmett-Teller	537:558	arg1	area					574:577	Brunauer-Emmett-Teller (BET) surface area	537:577	Brunauer-Emmett-Teller (BET) surface area	537:577	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	1	24	dep	geopolymers	171:181	arg1	GP5					188:190	GP5	188:190	GP5	188:190	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	24	dep	geopolymers	171:181	arg1	GP0					183:185	GP0	183:185	GP0	183:185	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	24	dep	geopolymers	171:181	arg1	geopolymers					171:181	four pozzolan-based geopolymers	151:181	four pozzolan-based geopolymers GP0, GP5, GP10, and GP20	151:206	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	24	dep	geopolymers	171:181	arg1	GP10					193:196	GP10	193:196	GP10	193:196	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	1	24	dep	geopolymers	171:181	arg1	GP20					203:206	GP20	203:206	GP20	203:206	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35949096	5	25	theme	isotherm	1081:1088	arg1	model					1090:1094	the Sips isotherm model	1072:1094	the Sips isotherm model	1072:1094	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	7	26	from	amount	1275:1280	arg1	volumes					1301:1307	different volumes	1291:1307	different volumes of effluent	1291:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	2	27	from	dye	634:636	arg1	medium					652:657	an aqueous medium	641:657	an aqueous medium	641:657	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	28	theme	X-ray	394:398	arg1	XRF					414:416	XRF	414:416	XRF	414:416	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	28	theme	X-ray	394:398	arg1	fluorescence					400:411	X-ray fluorescence	394:411	X-ray fluorescence (XRF)	394:417	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	8	29	theme	activated	1437:1445	arg1	carbon					1447:1452	commercial activated carbon	1426:1452	commercial activated carbon	1426:1452	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	2	30	dep	Fourier	445:451	arg1	transform					453:461	transform	453:461	transform infrared spectroscopy (FTIR)	453:490	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	5	31	theme	MB	961:962	arg1	kinetics					949:956	The sorption kinetics	936:956	The sorption kinetics of MB onto the composites	936:982	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	7	32	theme	different	1291:1299	arg1	volumes					1301:1307	different volumes	1291:1307	different volumes of effluent	1291:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	0	33	theme	bagasse	36:42	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of pozzolan and sugarcane bagasse	0:42	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	4	34	theme	biochar	852:858	arg1	content					860:866	biochar content	852:866	biochar content	852:866	The adsorption capacity increased with an increase in biochar content from 24.44 to 455.46 mg/g (18-fold) for GP0 and GP10, respectively.					
35949096	4	35	from	increase	840:847	arg1	content					860:866	biochar content	852:866	biochar content	852:866	The adsorption capacity increased with an increase in biochar content from 24.44 to 455.46 mg/g (18-fold) for GP0 and GP10, respectively.					
35949096	2	36	theme	batch	662:666	arg1	mode					668:671	batch mode	662:671	batch mode	662:671	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	7	37	from	MB	1285:1286	arg1	volumes					1301:1307	different volumes	1291:1307	different volumes of effluent	1291:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	0	38	theme	sugarcane	26:34	arg1	bagasse					36:42	sugarcane bagasse	26:42	sugarcane bagasse	26:42	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	2	39	theme	X-ray	420:424	arg1	XRD					439:441	XRD	439:441	XRD	439:441	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	39	theme	X-ray	420:424	arg1	diffraction					426:436	X-ray diffraction	420:436	X-ray diffraction (XRD)	420:442	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	7	40	theme	MB	1285:1286	arg1	amount					1275:1280	a fixed amount	1267:1280	a fixed amount of MB in different volumes of effluent	1267:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	40	theme	MB	1285:1286	arg1	MB					1285:1286	MB	1285:1286	MB in different volumes of effluent	1285:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	2	41	theme	MB	630:631	arg1	dye					634:636	methylene blue (MB) dye	614:636	methylene blue (MB) dye in an aqueous medium	614:657	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	0	42	theme	geopolymer-biochar	52:69	arg1	composites					71:80	geopolymer-biochar composites	52:80	geopolymer-biochar composites for methylene blue sequestration from aqueous medium	52:133	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	3	43	theme	alkaline	678:685	arg1	activation					687:696	The alkaline activation	674:696	The alkaline activation of pozzolan-biochar blends	674:723	The alkaline activation of pozzolan-biochar blends resulted in the formation of poly (Ferro-sialate-siloxo)-biochar chains.					
35949096	4	44	theme	adsorption	802:811	arg1	capacity					813:820	The adsorption capacity	798:820	The adsorption capacity	798:820	The adsorption capacity increased with an increase in biochar content from 24.44 to 455.46 mg/g (18-fold) for GP0 and GP10, respectively.					
35949096	8	45	theme	suitable	1462:1469	arg1	candidates					1483:1492	suitable alternative candidates	1462:1492	suitable alternative candidates for the removal of dyes from water	1462:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	7	46	theme	fixed	1269:1273	arg1	amount					1275:1280	a fixed amount	1267:1280	a fixed amount of MB in different volumes of effluent	1267:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	46	theme	fixed	1269:1273	arg1	MB					1285:1286	MB	1285:1286	MB in different volumes of effluent	1285:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	4	47	dep	455.46 mg/g	882:892	arg1	18-fold					895:901	18-fold	895:901	18-fold	895:901	The adsorption capacity increased with an increase in biochar content from 24.44 to 455.46 mg/g (18-fold) for GP0 and GP10, respectively.					
35949096	8	48	theme	dyes	1513:1516	arg1	removal					1502:1508	the removal	1498:1508	the removal of dyes from water	1498:1527	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	0	49	from	medium	128:133	arg1	sequestration					101:113	methylene blue sequestration	86:113	methylene blue sequestration from aqueous medium	86:133	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	7	50	theme	amount	1275:1280	arg1	amount					1275:1280	a fixed amount	1267:1280	a fixed amount of MB in different volumes of effluent	1267:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	50	theme	amount	1275:1280	arg1	%					1262:1262	99%	1260:1262	99% of a fixed amount of MB in different volumes of effluent	1260:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	50	theme	amount	1275:1280	arg1	MB					1285:1286	MB	1285:1286	MB in different volumes of effluent	1285:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	2	51	theme	blue	624:627	arg1	dye					634:636	methylene blue (MB) dye	614:636	methylene blue (MB) dye in an aqueous medium	614:657	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	7	52	theme	%	1262:1262	arg1	removal					1249:1255	the removal	1245:1255	the removal of 99% of a fixed amount of MB in different volumes of effluent	1245:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	2	53	theme	electron	502:509	arg1	SEM/EDX					523:529	SEM/EDX	523:529	SEM/EDX	523:529	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	53	theme	electron	502:509	arg1	microscopy					511:520	scanning electron microscopy	493:520	scanning electron microscopy (SEM/EDX)	493:530	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	5	54	theme	sorption	940:947	arg1	kinetics					949:956	The sorption kinetics	936:956	The sorption kinetics of MB onto the composites	936:982	The sorption kinetics of MB onto the composites followed pseudo-second-order kinetics while the equilibrium data were best described by the Sips isotherm model.					
35949096	2	55	theme	methylene	614:622	arg1	dye					634:636	methylene blue (MB) dye	614:636	methylene blue (MB) dye in an aqueous medium	614:657	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	3	56	theme	pozzolan-biochar	701:716	arg1	blends					718:723	pozzolan-biochar blends	701:723	pozzolan-biochar blends	701:723	The alkaline activation of pozzolan-biochar blends resulted in the formation of poly (Ferro-sialate-siloxo)-biochar chains.					
35949096	2	57	theme	scanning	493:500	arg1	SEM/EDX					523:529	SEM/EDX	523:529	SEM/EDX	523:529	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	2	57	theme	scanning	493:500	arg1	microscopy					511:520	scanning electron microscopy	493:520	scanning electron microscopy (SEM/EDX)	493:530	The composites were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDX), and Brunauer-Emmett-Teller (BET) surface area analyses, and applied to sequester methylene blue (MB) dye in an aqueous medium in batch mode.					
35949096	7	58	from	volumes	1301:1307	arg1	amount					1275:1280	a fixed amount	1267:1280	a fixed amount of MB in different volumes of effluent	1267:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	58	from	volumes	1301:1307	arg1	MB					1285:1286	MB	1285:1286	MB in different volumes of effluent	1285:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	3	59	theme	blends	718:723	arg1	activation					687:696	The alkaline activation	674:696	The alkaline activation of pozzolan-biochar blends	674:723	The alkaline activation of pozzolan-biochar blends resulted in the formation of poly (Ferro-sialate-siloxo)-biochar chains.					
35949096	8	60	theme	efficient	1384:1392	arg1	eco-adsorbents					1406:1419	efficient and cheaper eco-adsorbents	1384:1419	efficient and cheaper eco-adsorbents than commercial activated carbon	1384:1452	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	8	60	theme	efficient	1384:1392	arg1	composites					1369:1378	the composites	1365:1378	the composites	1365:1378	Cost-analysis indicates that the composites are efficient and cheaper eco-adsorbents than commercial activated carbon and are suitable alternative candidates for the removal of dyes from water.					
35949096	6	61	theme	adsorption	1101:1110	arg1	process					1112:1118	The adsorption process	1097:1118	The adsorption process	1097:1118	The adsorption process was thermodynamically spontaneous, endothermic (ΔH = 14.32-32.20 kJ/mol), and physical.					
35949096	6	61	theme	adsorption	1101:1110	arg1	spontaneous					1142:1152	spontaneous	1142:1152	spontaneous	1142:1152	The adsorption process was thermodynamically spontaneous, endothermic (ΔH = 14.32-32.20 kJ/mol), and physical.					
35949096	7	62	theme	adsorbent	1222:1230	arg1	adsorbent					1222:1230	adsorbent	1222:1230	adsorbent	1222:1230	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	7	62	theme	adsorbent	1222:1230	arg1	amount					1212:1217	The amount	1208:1217	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent	1208:1319	The amount of adsorbent required for the removal of 99% of a fixed amount of MB in different volumes of effluent was predicted.					
35949096	0	63	theme	pozzolan	13:20	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of pozzolan and sugarcane bagasse	0:42	Synthesis of pozzolan and sugarcane bagasse derived geopolymer-biochar composites for methylene blue sequestration from aqueous medium.					
35949096	3	64	theme	chains	790:795	arg1	formation					741:749	the formation	737:749	the formation of poly (Ferro-sialate-siloxo)-biochar chains	737:795	The alkaline activation of pozzolan-biochar blends resulted in the formation of poly (Ferro-sialate-siloxo)-biochar chains.					
35949096	1	65	theme	alkaline	228:235	arg1	activation					237:246	alkaline activation	228:246	alkaline activation	228:246	In this study, four pozzolan-based geopolymers GP0, GP5, GP10, and GP20 were synthesized by alkaline activation and by substituting 0, 5, 10, and 20% of the precursor with sugarcane bagasse-derived biochar, respectively.					
35955962	8	0	theme	low	1452:1454	arg1	diet					1464:1467	a low FODMAPs diet	1450:1467	a low FODMAPs diet	1450:1467	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	3	1	theme	strategies	519:528	arg1	use					488:490	The use	484:490	The use of microbiota intervention strategies	484:528	The use of microbiota intervention strategies may be an approach to consider in the management of these cases.					
35955962	3	1	theme	strategies	519:528	arg1	approach					540:547	an approach	537:547	an approach to consider in the management of these cases	537:592	The use of microbiota intervention strategies may be an approach to consider in the management of these cases.					
35955962	5	2	theme	neurological	1148:1159	arg1	symptoms					1188:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	5	3	dep	diet	1006:1009	arg1	aim					1127:1129	the aim	1123:1129	the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition	1123:1250	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	5	4	theme	metabolic	1162:1170	arg1	symptoms					1188:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	12	5	from	correlation	1982:1992	arg1	physiopathology					2074:2088	the physiopathology	2070:2088	the physiopathology of ASD	2070:2095	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	9	6	theme	gut	1598:1600	arg1	analysis					1613:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis showed reductions in Actinobacteria, Firmicutes, Lactobacilli, and Bifidobacteria.					
35955962	7	7	theme	intestinal	1361:1370	arg1	symptoms					1372:1379	her intestinal symptoms	1357:1379	her intestinal symptoms	1357:1379	Although her intestinal symptoms improved, KD was poorly tolerated.					
35955962	0	8	theme	Microbiota	192:201	arg1	Effects					170:176	Effects	170:176	Effects of Intestinal Microbiota	170:201	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	0	8	theme	Microbiota	192:201	arg1	Response					157:164	Clinical Response	148:164	Clinical Response	148:164	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	4	9	from	ASD	650:652	arg1	PGM1					720:723	PGM1	720:723	PGM1	720:723	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	9	from	ASD	650:652	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	10	theme	reduced	655:661	arg1	growth					663:668	reduced growth	655:668	reduced growth	655:668	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	11	theme	17-year-old	621:631	arg1	girl					633:636	a 17-year-old girl	619:636	a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss	619:880	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	10	12	theme	alpha	1709:1713	arg1	biodiversity					1715:1726	The alpha biodiversity	1705:1726	The alpha biodiversity	1705:1726	The alpha biodiversity was consistently increased and the Firmicutes/Bacteroidetes ratio decreased, reducing the extent of fermentative dysbiosis.					
35955962	0	13	theme	Responsive	123:132	arg1	Epilepsy					89:96	Epilepsy	89:96	Epilepsy	89:96	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	5	14	theme	fermentable	1030:1040	arg1	FODMAP					1104:1109	FODMAP	1104:1109	FODMAP	1104:1109	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	5	14	theme	fermentable	1030:1040	arg1	oligosaccharides					1042:1057	a low fermentable oligosaccharides	1024:1057	a low fermentable oligosaccharides	1024:1057	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	1	15	theme	spectrum	211:218	arg1	ASD					230:232	ASD	230:232	ASD	230:232	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	15	theme	spectrum	211:218	arg1	disorder					220:227	Autism spectrum disorder	204:227	Autism spectrum disorder (ASD)	204:233	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	6	16	theme	ketogenic	1257:1265	arg1	KD					1273:1274	KD	1273:1274	KD	1273:1274	The ketogenic diet (KD) provided a reduction in Firmicutes, Bacteroidetes, and Proteobacteria.					
35955962	6	16	theme	ketogenic	1257:1265	arg1	diet					1267:1270	The ketogenic diet	1253:1270	The ketogenic diet (KD)	1253:1275	The ketogenic diet (KD) provided a reduction in Firmicutes, Bacteroidetes, and Proteobacteria.					
35955962	3	17	theme	cases	588:592	arg1	management					568:577	the management	564:577	the management of these cases	564:592	The use of microbiota intervention strategies may be an approach to consider in the management of these cases.					
35955962	12	18	from	involvement	2055:2065	arg1	physiopathology					2074:2088	the physiopathology	2070:2088	the physiopathology of ASD	2070:2095	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	0	19	theme	Clinical	148:155	arg1	Response					157:164	Clinical Response	148:164	Clinical Response	148:164	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	1	20	theme	neurological	317:328	arg1	manifestations					330:343	neurological manifestations	317:343	several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E)	260:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	20	theme	neurological	317:328	arg1	epilepsy					353:360	epilepsy	353:360	epilepsy (ASD-E)	353:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	2	21	from	aspects	436:442	arg1	terms					447:451	terms	447:451	terms of gut microbiota composition	447:481	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	4	22	theme	development	684:694	arg1	delay					696:700	neurological development delay	671:700	neurological development delay	671:700	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	0	23	theme	Young	61:65	arg1	Patient					76:82	a Young Autistic Patient	59:82	a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies	59:145	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	0	24	theme	Patient	76:82	arg1	Management					45:54	Therapeutic Management	33:54	Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies	33:145	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	6	25	from	reduction	1288:1296	arg1	Bacteroidetes					1313:1325	Bacteroidetes	1313:1325	Bacteroidetes	1313:1325	The ketogenic diet (KD) provided a reduction in Firmicutes, Bacteroidetes, and Proteobacteria.					
35955962	6	25	from	reduction	1288:1296	arg1	Proteobacteria					1332:1345	Proteobacteria	1332:1345	Proteobacteria	1332:1345	The ketogenic diet (KD) provided a reduction in Firmicutes, Bacteroidetes, and Proteobacteria.					
35955962	6	25	from	reduction	1288:1296	arg1	Firmicutes					1301:1310	Firmicutes	1301:1310	Firmicutes	1301:1310	The ketogenic diet (KD) provided a reduction in Firmicutes, Bacteroidetes, and Proteobacteria.					
35955962	4	26	from	disorders	808:816	arg1	PGM1					720:723	PGM1	720:723	PGM1	720:723	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	26	from	disorders	808:816	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	0	27	from	Diet	25:28	arg1	Management					45:54	Therapeutic Management	33:54	Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies	33:145	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	0	28	theme	Ketogenic	0:8	arg1	Diet					25:28	Ketogenic and Low FODMAP Diet	0:28	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.	0:202	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	1	29	theme	several	260:266	arg1	epilepsy					353:360	epilepsy	353:360	epilepsy (ASD-E)	353:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	29	theme	several	260:266	arg1	disorders					296:304	several intestinal and/or metabolic disorders	260:304	several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E)	260:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	4	30	from	PGM1	720:723	arg1	absence					750:756	the absence	746:756	the absence of clinically manifested disease	746:789	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	31	theme	EEF1A2	729:734	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	2	32	theme	common	429:434	arg1	aspects					436:442	common aspects	429:442	common aspects in terms of gut microbiota composition	429:481	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	0	33	theme	Low	14:16	arg1	Diet					25:28	Ketogenic and Low FODMAP Diet	0:28	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.	0:202	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	2	34	theme	microbiota	460:469	arg1	composition					471:481	gut microbiota composition	456:481	gut microbiota composition	456:481	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	0	35	theme	Therapeutic	33:43	arg1	Management					45:54	Therapeutic Management	33:54	Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies	33:145	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	4	36	theme	intestinal	797:806	arg1	pain					836:839	abdominal pain	826:839	abdominal pain	826:839	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	36	theme	intestinal	797:806	arg1	disorders					808:816	intestinal disorders	797:816	intestinal disorders such as abdominal pain and diarrhea associated with weight loss	797:880	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	36	theme	intestinal	797:806	arg1	diarrhea					845:852	diarrhea	845:852	diarrhea	845:852	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	37	from	mutations	703:711	arg1	PGM1					720:723	PGM1	720:723	PGM1	720:723	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	37	from	mutations	703:711	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	0	38	dep	Diet	25:28	arg1	Effects					170:176	Effects	170:176	Effects of Intestinal Microbiota	170:201	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	0	38	dep	Diet	25:28	arg1	Response					157:164	Clinical Response	148:164	Clinical Response	148:164	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	10	39	theme	dysbiosis	1841:1849	arg1	extent					1818:1823	the extent	1814:1823	the extent of fermentative dysbiosis	1814:1849	The alpha biodiversity was consistently increased and the Firmicutes/Bacteroidetes ratio decreased, reducing the extent of fermentative dysbiosis.					
35955962	4	40	theme	manifested	772:781	arg1	disease					783:789	clinically manifested disease	761:789	clinically manifested disease	761:789	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	11	41	theme	Gut	1852:1854	arg1	target					1890:1895	a therapeutic target	1876:1895	a therapeutic target to improve ASD-related symptoms	1876:1927	Gut microbiota could be a therapeutic target to improve ASD-related symptoms.					
35955962	11	41	theme	Gut	1852:1854	arg1	microbiota					1856:1865	Gut microbiota	1852:1865	Gut microbiota	1852:1865	Gut microbiota could be a therapeutic target to improve ASD-related symptoms.					
35955962	4	42	from	delay	696:700	arg1	PGM1					720:723	PGM1	720:723	PGM1	720:723	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	42	from	delay	696:700	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	5	43	theme	intestinal	1177:1186	arg1	symptoms					1188:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	her neurological, metabolic, and intestinal symptoms	1144:1195	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	12	44	theme	gut	2002:2004	arg1	composition					2017:2027	gut microbiota composition	2002:2027	gut microbiota composition	2002:2027	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	5	45	theme	dietary	976:982	arg1	patterns					984:991	two specific dietary patterns	963:991	two specific dietary patterns	963:991	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	3	46	theme	intervention	506:517	arg1	strategies					519:528	microbiota intervention strategies	495:528	microbiota intervention strategies	495:528	The use of microbiota intervention strategies may be an approach to consider in the management of these cases.					
35955962	4	47	theme	abdominal	826:834	arg1	pain					836:839	abdominal pain	826:839	abdominal pain	826:839	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	8	48	theme	metabolic	1541:1549	arg1	symptoms					1551:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	0	49	theme	Intestinal	181:190	arg1	Microbiota					192:201	Intestinal Microbiota	181:201	Intestinal Microbiota	181:201	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	4	50	from	growth	663:668	arg1	PGM1					720:723	PGM1	720:723	PGM1	720:723	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	50	from	growth	663:668	arg1	genes					736:740	EEF1A2 genes	729:740	EEF1A2 genes	729:740	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	9	51	theme	following	1588:1596	arg1	analysis					1613:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis showed reductions in Actinobacteria, Firmicutes, Lactobacilli, and Bifidobacteria.					
35955962	9	52	theme	microbiota	1602:1611	arg1	analysis					1613:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis	1584:1620	The following gut microbiota analysis showed reductions in Actinobacteria, Firmicutes, Lactobacilli, and Bifidobacteria.					
35955962	0	53	with	Patient	76:82	arg1	Dysmetabolism					102:114	Dysmetabolism	102:114	Dysmetabolism	102:114	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	0	53	with	Patient	76:82	arg1	Epilepsy					89:96	Epilepsy	89:96	Epilepsy	89:96	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	5	54	theme	low	1026:1028	arg1	FODMAP					1104:1109	FODMAP	1104:1109	FODMAP	1104:1109	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	5	54	theme	low	1026:1028	arg1	oligosaccharides					1042:1057	a low fermentable oligosaccharides	1024:1057	a low fermentable oligosaccharides	1024:1057	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	10	55	theme	Firmicutes/Bacteroidetes	1763:1786	arg1	ratio					1788:1792	the Firmicutes/Bacteroidetes ratio	1759:1792	the Firmicutes/Bacteroidetes ratio	1759:1792	The alpha biodiversity was consistently increased and the Firmicutes/Bacteroidetes ratio decreased, reducing the extent of fermentative dysbiosis.					
35955962	1	56	theme	Autism	204:209	arg1	ASD					230:232	ASD	230:232	ASD	230:232	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	56	theme	Autism	204:209	arg1	disorder					220:227	Autism spectrum disorder	204:227	Autism spectrum disorder (ASD)	204:233	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	4	57	theme	girl	633:636	arg1	case					611:614	the case	607:614	the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss	607:880	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	5	58	theme	oligosaccharides	1042:1057	arg1	diet					1112:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	12	59	theme	Further	1930:1936	arg1	studies					1938:1944	Further studies	1930:1944	Further studies	1930:1944	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	12	60	theme	possible	2046:2053	arg1	involvement					2055:2065	its possible involvement	2042:2065	its possible involvement in the physiopathology of ASD	2042:2095	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	5	61	theme	gut	1223:1225	arg1	composition					1240:1250	the gut microbiota's composition	1219:1250	the gut microbiota's composition	1219:1250	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	4	62	dep	PGM1	720:723	arg1	the					716:718	the	716:718	the	716:718	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	4	63	theme	weight	870:875	arg1	loss					877:880	weight loss	870:880	weight loss	870:880	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	8	64	theme	other	1423:1427	arg1	hand					1429:1432	the other hand	1419:1432	the other hand	1419:1432	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	0	65	theme	Autistic	67:74	arg1	Patient					76:82	a Young Autistic Patient	59:82	a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies	59:145	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	5	66	theme	polyols	1095:1101	arg1	diet					1112:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	4	67	theme	neurological	671:682	arg1	delay					696:700	neurological development delay	671:700	neurological development delay	671:700	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	9	68	from	reductions	1629:1638	arg1	Firmicutes					1659:1668	Firmicutes	1659:1668	Firmicutes	1659:1668	The following gut microbiota analysis showed reductions in Actinobacteria, Firmicutes, Lactobacilli, and Bifidobacteria.					
35955962	5	69	theme	disaccharides	1060:1072	arg1	diet					1112:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	4	70	from	genes	736:740	arg1	absence					750:756	the absence	746:756	the absence of clinically manifested disease	746:789	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	8	71	theme	FODMAPs	1456:1462	arg1	diet					1464:1467	a low FODMAPs diet	1450:1467	a low FODMAPs diet	1450:1467	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	11	72	theme	therapeutic	1878:1888	arg1	target					1890:1895	a therapeutic target	1876:1895	a therapeutic target to improve ASD-related symptoms	1876:1927	Gut microbiota could be a therapeutic target to improve ASD-related symptoms.					
35955962	11	72	theme	therapeutic	1878:1888	arg1	microbiota					1856:1865	Gut microbiota	1852:1865	Gut microbiota	1852:1865	Gut microbiota could be a therapeutic target to improve ASD-related symptoms.					
35955962	5	73	theme	monosaccharides	1075:1089	arg1	diet					1112:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet	1024:1115	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	5	74	theme	poor	903:906	arg1	responsiveness					908:921	poor responsiveness	903:921	poor responsiveness to the therapies provided	903:947	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	0	75	theme	FODMAP	18:23	arg1	Diet					25:28	Ketogenic and Low FODMAP Diet	0:28	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.	0:202	Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.					
35955962	1	76	theme	intestinal	268:277	arg1	epilepsy					353:360	epilepsy	353:360	epilepsy (ASD-E)	353:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	76	theme	intestinal	268:277	arg1	disorders					296:304	several intestinal and/or metabolic disorders	260:304	several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E)	260:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	8	77	theme	significant	1480:1490	arg1	improvement					1492:1502	a significant improvement	1478:1502	a significant improvement	1478:1502	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	10	78	theme	fermentative	1828:1839	arg1	dysbiosis					1841:1849	fermentative dysbiosis	1828:1849	fermentative dysbiosis	1828:1849	The alpha biodiversity was consistently increased and the Firmicutes/Bacteroidetes ratio decreased, reducing the extent of fermentative dysbiosis.					
35955962	11	79	theme	ASD-related	1908:1918	arg1	symptoms					1920:1927	ASD-related symptoms	1908:1927	ASD-related symptoms	1908:1927	Gut microbiota could be a therapeutic target to improve ASD-related symptoms.					
35955962	1	80	theme	metabolic	286:294	arg1	epilepsy					353:360	epilepsy	353:360	epilepsy (ASD-E)	353:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	1	80	theme	metabolic	286:294	arg1	disorders					296:304	several intestinal and/or metabolic disorders	260:304	several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E)	260:368	Autism spectrum disorder (ASD) is often associated with several intestinal and/or metabolic disorders as well as neurological manifestations such as epilepsy (ASD-E).					
35955962	2	81	theme	composition	471:481	arg1	terms					447:451	terms	447:451	terms of gut microbiota composition	447:481	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	4	82	theme	disease	783:789	arg1	absence					750:756	the absence	746:756	the absence of clinically manifested disease	746:789	We describe the case of a 17-year-old girl affected by ASD, reduced growth, neurological development delay, mutations in the PGM1 and EEF1A2 genes (in the absence of clinically manifested disease) and, intestinal disorders such as abdominal pain and diarrhea associated with weight loss.					
35955962	2	83	theme	neuropathological	394:410	arg1	conditions					412:421	these neuropathological conditions	388:421	these neuropathological conditions	388:421	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	2	84	theme	gut	456:458	arg1	composition					471:481	gut microbiota composition	456:481	gut microbiota composition	456:481	Those presenting these neuropathological conditions share common aspects in terms of gut microbiota composition.					
35955962	8	85	theme	neurological	1511:1522	arg1	symptoms					1551:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	5	86	theme	ketogenic	996:1004	arg1	diet					1006:1009	a ketogenic diet	994:1009	a ketogenic diet	994:1009	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
35955962	3	87	theme	microbiota	495:504	arg1	strategies					519:528	microbiota intervention strategies	495:528	microbiota intervention strategies	495:528	The use of microbiota intervention strategies may be an approach to consider in the management of these cases.					
35955962	8	88	theme	intestinal	1525:1534	arg1	symptoms					1551:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	all neurological, intestinal, and metabolic symptoms	1507:1558	On the other hand, the passage to a low FODMAPs diet produced a significant improvement in all neurological, intestinal, and metabolic symptoms and was well-tolerated.					
35955962	12	89	theme	microbiota	2006:2015	arg1	composition					2017:2027	gut microbiota composition	2002:2027	gut microbiota composition	2002:2027	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	12	90	theme	ASD	2093:2095	arg1	physiopathology					2074:2088	the physiopathology	2070:2088	the physiopathology of ASD	2070:2095	Further studies are needed to better understand the correlation between gut microbiota composition and ASD, and its possible involvement in the physiopathology of ASD.					
35955962	5	91	theme	specific	967:974	arg1	patterns					984:991	two specific dietary patterns	963:991	two specific dietary patterns	963:991	As she demonstrated poor responsiveness to the therapies provided, we attempted two specific dietary patterns: a ketogenic diet, followed by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet, with the aim of improving her neurological, metabolic, and intestinal symptoms through modulation of the gut microbiota's composition.					
36087757	1	0	theme	fibrocartilaginous	163:180	arg1	meniscus					149:156	The meniscus	145:156	The meniscus	145:156	The meniscus is a fibrocartilaginous tissue that is very important for the stability of the knee joint.					
36087757	1	0	theme	fibrocartilaginous	163:180	arg1	important					202:210	important	202:210	important	202:210	The meniscus is a fibrocartilaginous tissue that is very important for the stability of the knee joint.					
36087757	1	0	theme	fibrocartilaginous	163:180	arg1	tissue					182:187	a fibrocartilaginous tissue	161:187	a fibrocartilaginous tissue that is very important for the stability of the knee joint	161:246	The meniscus is a fibrocartilaginous tissue that is very important for the stability of the knee joint.					
36087757	0	1	theme	hydrogel	80:87	arg1	scaffolds					89:97	hydrogel scaffolds	80:97	hydrogel scaffolds	80:97	Loofah-chitosan and poly (-3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) based hydrogel scaffolds for meniscus tissue engineering applications.					
36087757	3	2	theme	loofah	450:455	arg1	mat					457:459	loofah mat	450:459	loofah mat	450:459	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	8	3	theme	promising	1353:1361	arg1	material					1363:1370	a promising material	1351:1370	a promising material for engineering meniscus tissue	1351:1402	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	8	3	theme	promising	1353:1361	arg1	scaffold					1339:1346	the hydrogel composite scaffold	1316:1346	the hydrogel composite scaffold	1316:1346	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	0	4	theme	meniscus	103:110	arg1	applications					131:142	meniscus tissue engineering applications	103:142	meniscus tissue engineering applications	103:142	Loofah-chitosan and poly (-3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) based hydrogel scaffolds for meniscus tissue engineering applications.					
36087757	3	5	theme	temperature	609:619	arg1	terms					538:542	terms	538:542	terms of their shape, chemical composition, mechanical properties, and temperature	538:619	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	5	6	theme	chondrogenic	906:917	arg1	potential					919:927	the chondrogenic potential	902:927	the chondrogenic potential of hydrogel scaffolds	902:949	Scaffolds were seeded using undifferentiated MSCs and incubated for 21 days to investigate the chondrogenic potential of hydrogel scaffolds.					
36087757	6	7	theme	cell	1095:1098	arg1	attachment					1100:1109	cell attachment	1095:1109	cell attachment	1095:1109	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	6	8	theme	SEM	1040:1042	arg1	morphologies					1078:1089	SEM and fluorescence imaging observed morphologies	1040:1089	SEM and fluorescence imaging observed morphologies	1040:1089	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	4	9	theme	genipin	656:662	arg1	concentrations					638:651	Three different concentrations	622:651	Three different concentrations of genipin (0.1, 0.3, and 0.5 %)	622:684	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	2	10	contain	has	261:263	arg1	it					258:259	it	258:259	it	258:259	However, it has a low ability to heal itself, so damage to it will always lead to articular cartilage degeneration.					
36087757	2	10	contain	has	261:263	arg2	ability					271:277	a low ability	265:277	a low ability to heal itself	265:292	However, it has a low ability to heal itself, so damage to it will always lead to articular cartilage degeneration.					
36087757	0	11	theme	engineering	119:129	arg1	applications					131:142	meniscus tissue engineering applications	103:142	meniscus tissue engineering applications	103:142	Loofah-chitosan and poly (-3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) based hydrogel scaffolds for meniscus tissue engineering applications.					
36087757	6	12	theme	Cell	952:955	arg1	analyses					971:978	Cell proliferation analyses	952:978	Cell proliferation analyses	952:978	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	2	13	theme	low	267:269	arg1	ability					271:277	a low ability	265:277	a low ability to heal itself	265:292	However, it has a low ability to heal itself, so damage to it will always lead to articular cartilage degeneration.					
36087757	0	14	theme	tissue	112:117	arg1	applications					131:142	meniscus tissue engineering applications	103:142	meniscus tissue engineering applications	103:142	Loofah-chitosan and poly (-3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) based hydrogel scaffolds for meniscus tissue engineering applications.					
36087757	3	15	theme	PHBV	466:469	arg1	nanofibers					471:480	PHBV nanofibers	466:480	PHBV nanofibers	466:480	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	6	16	theme	WST-1	1001:1005	arg1	assay					1007:1011	WST-1 assay	1001:1011	WST-1 assay	1001:1011	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	7	17	theme	cytotoxic	1209:1217	arg1	effect					1219:1224	no cytotoxic effect	1206:1224	no cytotoxic effect	1206:1224	The in vitro analysis showed no cytotoxic effect and enabled cells to attach, proliferate, and migrate inside the scaffold.					
36087757	6	18	theme	imaging	1061:1067	arg1	morphologies					1078:1089	SEM and fluorescence imaging observed morphologies	1040:1089	SEM and fluorescence imaging observed morphologies	1040:1089	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	5	19	theme	scaffolds	941:949	arg1	potential					919:927	the chondrogenic potential	902:927	the chondrogenic potential of hydrogel scaffolds	902:949	Scaffolds were seeded using undifferentiated MSCs and incubated for 21 days to investigate the chondrogenic potential of hydrogel scaffolds.					
36087757	4	20	used	used	691:694	arg2	concentrations					638:651	Three different concentrations	622:651	Three different concentrations of genipin (0.1, 0.3, and 0.5 %)	622:684	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	2	21	theme	cartilage	341:349	arg1	degeneration					351:362	articular cartilage degeneration	331:362	articular cartilage degeneration	331:362	However, it has a low ability to heal itself, so damage to it will always lead to articular cartilage degeneration.					
36087757	4	22	theme	crosslinker	712:722	arg1	%					746:746	0.3 %	742:746	0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF)	742:808	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	4	22	theme	crosslinker	712:722	arg1	concentration					724:736	the optimal crosslinker concentration	700:736	the optimal crosslinker concentration	700:736	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	4	23	theme	optimal	704:710	arg1	%					746:746	0.3 %	742:746	0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF)	742:808	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	4	23	theme	optimal	704:710	arg1	concentration					724:736	the optimal crosslinker concentration	700:736	the optimal crosslinker concentration	700:736	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	5	24	theme	hydrogel	932:939	arg1	scaffolds					941:949	hydrogel scaffolds	932:949	hydrogel scaffolds	932:949	Scaffolds were seeded using undifferentiated MSCs and incubated for 21 days to investigate the chondrogenic potential of hydrogel scaffolds.					
36087757	6	25	theme	fluorescence	1048:1059	arg1	imaging					1061:1067	fluorescence imaging	1048:1067	fluorescence imaging	1048:1067	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	3	26	theme	chemical	560:567	arg1	composition					569:579	chemical composition	560:579	chemical composition	560:579	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	5	27	theme	undifferentiated	839:854	arg1	MSCs					856:859	undifferentiated MSCs	839:859	undifferentiated MSCs	839:859	Scaffolds were seeded using undifferentiated MSCs and incubated for 21 days to investigate the chondrogenic potential of hydrogel scaffolds.					
36087757	3	28	theme	meniscus	414:421	arg1	scaffold					423:430	meniscus scaffold	414:430	meniscus scaffold	414:430	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	7	29	dep	in	1181:1182	arg1	vitro					1184:1188	vitro	1184:1188	vitro	1184:1188	The in vitro analysis showed no cytotoxic effect and enabled cells to attach, proliferate, and migrate inside the scaffold.					
36087757	3	30	theme	composition	569:579	arg1	terms					538:542	terms	538:542	terms of their shape, chemical composition, mechanical properties, and temperature	538:619	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	3	31	theme	composite	515:523	arg1	scaffolds					525:533	hydrogel composite scaffolds	506:533	hydrogel composite scaffolds	506:533	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	3	32	theme	new	402:404	arg1	type					406:409	a new type	400:409	a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers	400:480	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	3	33	theme	study	382:386	arg1	goal					369:372	The goal	365:372	The goal of this study	365:386	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	3	34	theme	shape	553:557	arg1	terms					538:542	terms	538:542	terms of their shape, chemical composition, mechanical properties, and temperature	538:619	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	8	35	theme	meniscus	1388:1395	arg1	tissue					1397:1402	meniscus tissue	1388:1402	meniscus tissue	1388:1402	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	4	36	theme	Chitosan/loofah/PHBV	777:796	arg1	fiber					798:802	Chitosan/loofah/PHBV fiber	777:802	Chitosan/loofah/PHBV fiber (CLF)	777:808	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	4	36	theme	Chitosan/loofah/PHBV	777:796	arg1	CLF					805:807	CLF	805:807	CLF	805:807	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	6	37	theme	immunohistochemical	1133:1151	arg1	studies					1153:1159	histological and immunohistochemical studies	1116:1159	histological and immunohistochemical studies	1116:1159	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	6	38	theme	GAG	1014:1016	arg1	content					1018:1024	GAG content	1014:1024	GAG content	1014:1024	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	3	39	theme	properties	593:602	arg1	terms					538:542	terms	538:542	terms of their shape, chemical composition, mechanical properties, and temperature	538:619	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	3	40	theme	hydrogel	506:513	arg1	scaffolds					525:533	hydrogel composite scaffolds	506:533	hydrogel composite scaffolds	506:533	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	4	41	theme	different	628:636	arg1	concentrations					638:651	Three different concentrations	622:651	Three different concentrations of genipin (0.1, 0.3, and 0.5 %)	622:684	Three different concentrations of genipin (0.1, 0.3, and 0.5 %) were used and the optimal crosslinker concentration was 0.3 % for Chitosan/loofah (CL) and Chitosan/loofah/PHBV fiber (CLF).					
36087757	8	42	theme	composite	1329:1337	arg1	material					1363:1370	a promising material	1351:1370	a promising material for engineering meniscus tissue	1351:1402	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	8	42	theme	composite	1329:1337	arg1	scaffold					1339:1346	the hydrogel composite scaffold	1316:1346	the hydrogel composite scaffold	1316:1346	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	6	43	theme	histological	1116:1127	arg1	studies					1153:1159	histological and immunohistochemical studies	1116:1159	histological and immunohistochemical studies	1116:1159	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	3	44	theme	scaffold	423:430	arg1	type					406:409	a new type	400:409	a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers	400:480	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	6	45	theme	observed	1069:1076	arg1	morphologies					1078:1089	SEM and fluorescence imaging observed morphologies	1040:1089	SEM and fluorescence imaging observed morphologies	1040:1089	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	8	46	theme	hydrogel	1320:1327	arg1	material					1363:1370	a promising material	1351:1370	a promising material for engineering meniscus tissue	1351:1402	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	8	46	theme	hydrogel	1320:1327	arg1	scaffold					1339:1346	the hydrogel composite scaffold	1316:1346	the hydrogel composite scaffold	1316:1346	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	1	47	theme	knee	237:240	arg1	joint					242:246	the knee joint	233:246	the knee joint	233:246	The meniscus is a fibrocartilaginous tissue that is very important for the stability of the knee joint.					
36087757	3	48	theme	mechanical	582:591	arg1	properties					593:602	mechanical properties	582:602	mechanical properties	582:602	The goal of this study was to make a new type of meniscus scaffold made of chitosan, loofah mat, and PHBV nanofibers, as well as to describe hydrogel composite scaffolds in terms of their shape, chemical composition, mechanical properties, and temperature.					
36087757	6	49	theme	proliferation	957:969	arg1	analyses					971:978	Cell proliferation analyses	952:978	Cell proliferation analyses	952:978	Cell proliferation analyses were performed using WST-1 assay, GAG content was analyzed, SEM and fluorescence imaging observed morphologies and cell attachment, and histological and immunohistochemical studies were performed.					
36087757	2	50	theme	articular	331:339	arg1	degeneration					351:362	articular cartilage degeneration	331:362	articular cartilage degeneration	331:362	However, it has a low ability to heal itself, so damage to it will always lead to articular cartilage degeneration.					
36087757	1	51	theme	joint	242:246	arg1	stability					220:228	the stability	216:228	the stability of the knee joint	216:246	The meniscus is a fibrocartilaginous tissue that is very important for the stability of the knee joint.					
36087757	8	52	from	material	1363:1370	arg1	conclusion					1304:1313	conclusion	1304:1313	conclusion	1304:1313	In conclusion, the hydrogel composite scaffold is a promising material for engineering meniscus tissue.					
36087757	7	53	theme	in	1181:1182	arg1	analysis					1190:1197	The in vitro analysis	1177:1197	The in vitro analysis	1177:1197	The in vitro analysis showed no cytotoxic effect and enabled cells to attach, proliferate, and migrate inside the scaffold.					
35450659	1	0	from	attractive	191:200	arg1	management					222:231	personal thermal management	205:231	personal thermal management	205:231	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	0	1	theme	thermal	87:93	arg1	management					95:104	personalized thermal management	74:104	personalized thermal management	74:104	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	5	2	theme	great	1197:1201	arg1	promise					1203:1209	great promise	1197:1209	great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection	1197:1307	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	5	3	theme	multifunctional	1114:1128	arg1	materials					1136:1144	multifunctional Janus materials	1114:1144	multifunctional Janus materials	1114:1144	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	2	4	theme	Janus	323:327	arg1	composite					340:348	a multifunctional Janus cellulosic composite	305:348	a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance	305:462	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	5	5	theme	efficient	1150:1158	arg1	management					1177:1186	efficient personal thermal management	1150:1186	efficient personal thermal management	1150:1186	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	2	6	theme	multifunctional	307:321	arg1	composite					340:348	a multifunctional Janus cellulosic composite	305:348	a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance	305:462	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	4	7	theme	infrared	1035:1042	arg1	radiation					1044:1052	infrared radiation	1035:1052	infrared radiation	1035:1052	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	2	8	theme	electrical	372:381	arg1	heating					383:389	superior electrical heating	363:389	superior electrical heating	363:389	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	5	9	theme	personal	1160:1167	arg1	management					1177:1186	efficient personal thermal management	1150:1186	efficient personal thermal management	1150:1186	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	2	10	theme	camouflage	441:450	arg1	performance					452:462	infrared camouflage performance	432:462	infrared camouflage performance	432:462	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	0	11	theme	thermal	52:58	arg1	functions					60:68	multiple thermal functions	43:68	multiple thermal functions for personalized thermal management	43:104	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	3	12	dep	PPy	817:819	arg1	the					789:791	the	789:791	the	789:791	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	4	13	theme	aerogel	882:888	arg1	CNFphobic					897:905	CNFphobic	897:905	CNFphobic	897:905	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	13	theme	aerogel	882:888	arg1	layer					890:894	The outward-facing hydrophobic aerogel layer	851:894	The outward-facing hydrophobic aerogel layer (CNFphobic)	851:906	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	13	theme	aerogel	882:888	arg1	insulator					930:938	the thermal insulator	918:938	the thermal insulator	918:938	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	3	14	theme	PEG	846:848	arg1	action					779:784	the joint action	769:784	the joint action of the electrically conductive PPy and thermally regulative PEG	769:848	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	2	15	theme	infrared	432:439	arg1	performance					452:462	infrared camouflage performance	432:462	infrared camouflage performance	432:462	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	0	16	theme	Janus	11:15	arg1	composite					28:36	Janus cellulosic composite	11:36	Janus cellulosic composite	11:36	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	3	17	theme	heating	743:749	arg1	on-demand					751:759	heating on-demand	743:759	heating on-demand	743:759	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	2	18	theme	superior	363:370	arg1	heating					383:389	superior electrical heating	363:389	superior electrical heating	363:389	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	2	19	theme	Janus	501:505	arg1	aerogel					534:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	1	20	theme	personal	205:212	arg1	management					222:231	personal thermal management	205:231	personal thermal management	205:231	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	2	21	theme	thermal	408:414	arg1	insulation					416:425	thermal insulation	408:425	thermal insulation	408:425	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	5	22	theme	effective	1077:1085	arg1	strategy					1098:1105	an effective and facile strategy	1074:1105	an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management	1074:1186	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	1	23	theme	effective	111:119	arg1	attractive					191:200	attractive	191:200	attractive	191:200	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	23	theme	effective	111:119	arg1	integration					121:131	The effective integration	107:131	The effective integration of multiple thermal functions into one material	107:179	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	24	theme	thermal	214:220	arg1	management					222:231	personal thermal management	205:231	personal thermal management	205:231	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	0	25	theme	cellulosic	17:26	arg1	composite					28:36	Janus cellulosic composite	11:36	Janus cellulosic composite	11:36	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	5	26	theme	thermal	1247:1253	arg1	comfort					1255:1261	thermal comfort	1247:1261	thermal comfort	1247:1261	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	4	27	theme	infrared	970:977	arg1	camouflage					979:988	infrared camouflage	970:988	infrared camouflage	970:988	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	2	28	theme	cellulosic	329:338	arg1	composite					340:348	a multifunctional Janus cellulosic composite	305:348	a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance	305:462	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	0	29	theme	multiple	43:50	arg1	functions					60:68	multiple thermal functions	43:68	multiple thermal functions for personalized thermal management	43:104	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	3	30	theme	joint	773:777	arg1	action					779:784	the joint action	769:784	the joint action of the electrically conductive PPy and thermally regulative PEG	769:848	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	5	31	theme	Janus	1130:1134	arg1	materials					1136:1144	multifunctional Janus materials	1114:1144	multifunctional Janus materials	1114:1144	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	3	32	theme	active	610:615	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	32	theme	active	610:615	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	5	33	theme	infrared	1264:1271	arg1	camouflage					1273:1282	infrared camouflage	1264:1282	infrared camouflage	1264:1282	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	2	34	theme	CNF	529:531	arg1	aerogel					534:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	3	35	theme	conductive	806:815	arg1	PPy					817:819	electrically conductive PPy	793:819	electrically conductive PPy	793:819	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	2	36	theme	polyethylene	566:577	arg1	PEG					587:589	PEG	587:589	PEG	587:589	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	2	36	theme	polyethylene	566:577	arg1	glycol					579:584	polyethylene glycol	566:584	polyethylene glycol (PEG)	566:590	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	3	37	theme	@	654:654	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	37	theme	@	654:654	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	38	theme	heating-thermal	617:631	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	38	theme	heating-thermal	617:631	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	4	39	theme	heat	1002:1005	arg1	loss					1007:1010	heat loss	1002:1010	heat loss	1002:1010	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	3	40	theme	PPy	817:819	arg1	action					779:784	the joint action	769:784	the joint action of the electrically conductive PPy and thermally regulative PEG	769:848	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	5	41	theme	facile	1091:1096	arg1	strategy					1098:1105	an effective and facile strategy	1074:1105	an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management	1074:1186	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	4	42	theme	hydrophobic	870:880	arg1	CNFphobic					897:905	CNFphobic	897:905	CNFphobic	897:905	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	42	theme	hydrophobic	870:880	arg1	layer					890:894	The outward-facing hydrophobic aerogel layer	851:894	The outward-facing hydrophobic aerogel layer (CNFphobic)	851:906	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	42	theme	hydrophobic	870:880	arg1	insulator					930:938	the thermal insulator	918:938	the thermal insulator	918:938	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	5	43	theme	thermal	1169:1175	arg1	management					1177:1186	efficient personal thermal management	1150:1186	efficient personal thermal management	1150:1186	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	2	44	theme	energy	392:397	arg1	storage					399:405	energy storage	392:405	energy storage	392:405	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	2	45	theme	nanofibers	517:526	arg1	aerogel					534:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	4	46	theme	thermal	922:928	arg1	insulator					930:938	the thermal insulator	918:938	the thermal insulator	918:938	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	46	theme	thermal	922:928	arg1	layer					890:894	The outward-facing hydrophobic aerogel layer	851:894	The outward-facing hydrophobic aerogel layer (CNFphobic)	851:906	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	3	47	theme	cellulosic	695:704	arg1	composite					706:714	multifunctional Janus cellulosic composite	673:714	multifunctional Janus cellulosic composite	673:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	4	48	theme	outward-facing	855:868	arg1	CNFphobic					897:905	CNFphobic	897:905	CNFphobic	897:905	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	48	theme	outward-facing	855:868	arg1	layer					890:894	The outward-facing hydrophobic aerogel layer	851:894	The outward-facing hydrophobic aerogel layer (CNFphobic)	851:906	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	4	48	theme	outward-facing	855:868	arg1	insulator					930:938	the thermal insulator	918:938	the thermal insulator	918:938	The outward-facing hydrophobic aerogel layer (CNFphobic) serves as the thermal insulator, which simultaneously enables infrared camouflage by reducing heat loss to the environment via infrared radiation.					
35450659	1	49	theme	multiple	136:143	arg1	functions					153:161	multiple thermal functions	136:161	multiple thermal functions	136:161	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	5	50	theme	security	1289:1296	arg1	protection					1298:1307	security protection	1289:1307	security protection	1289:1307	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	3	51	theme	composite	706:714	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	51	theme	composite	706:714	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	1	52	from	management	222:231	arg1	attractive					191:200	attractive	191:200	attractive	191:200	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	52	from	management	222:231	arg1	integration					121:131	The effective integration	107:131	The effective integration of multiple thermal functions into one material	107:179	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	53	theme	thermal	145:151	arg1	functions					153:161	multiple thermal functions	136:161	multiple thermal functions	136:161	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	3	54	theme	regulative	835:844	arg1	PEG					846:848	thermally regulative PEG	825:848	thermally regulative PEG	825:848	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	55	theme	multifunctional	673:687	arg1	composite					706:714	multifunctional Janus cellulosic composite	673:714	multifunctional Janus cellulosic composite	673:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	56	theme	PPy	651:653	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	56	theme	PPy	651:653	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	1	57	theme	functions	153:161	arg1	attractive					191:200	attractive	191:200	attractive	191:200	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	57	theme	functions	153:161	arg1	integration					121:131	The effective integration	107:131	The effective integration of multiple thermal functions into one material	107:179	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	1	58	theme	complex	245:251	arg1	environment					265:275	the complex application environment	241:275	the complex application environment	241:275	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	0	59	theme	personalized	74:85	arg1	management					95:104	personalized thermal management	74:104	personalized thermal management	74:104	Integrated Janus cellulosic composite with multiple thermal functions for personalized thermal management.					
35450659	3	60	theme	Janus	689:693	arg1	composite					706:714	multifunctional Janus cellulosic composite	673:714	multifunctional Janus cellulosic composite	673:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	61	theme	regulation	633:642	arg1	layer					644:648	the active heating-thermal regulation layer	606:648	the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite	606:714	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	3	61	theme	regulation	633:642	arg1	CNFphilic-PEG					655:667	PPy@CNFphilic-PEG	651:667	PPy@CNFphilic-PEG	651:667	In practice, the active heating-thermal regulation layer (PPy@CNFphilic-PEG) of multifunctional Janus cellulosic composite is faced inward to provide heating on-demand through the joint action of the electrically conductive PPy and thermally regulative PEG.					
35450659	1	62	theme	application	253:263	arg1	environment					265:275	the complex application environment	241:275	the complex application environment	241:275	The effective integration of multiple thermal functions into one material is highly attractive in personal thermal management, taking the complex application environment into consideration.					
35450659	2	63	theme	cellulose	507:515	arg1	aerogel					534:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Janus cellulose nanofibers (CNF) aerogel	501:540	Herein, a multifunctional Janus cellulosic composite encompassing superior electrical heating, energy storage, thermal insulation, and infrared camouflage performance was firstly developed by integrating Janus cellulose nanofibers (CNF) aerogel, polypyrrole (PPy), and polyethylene glycol (PEG).					
35450659	5	64	theme	potential	1215:1223	arg1	applications					1225:1236	potential applications	1215:1236	potential applications	1215:1236	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	5	64	theme	potential	1215:1223	arg1	camouflage					1273:1282	infrared camouflage	1264:1282	infrared camouflage	1264:1282	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	5	64	theme	potential	1215:1223	arg1	protection					1298:1307	security protection	1289:1307	security protection	1289:1307	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
35450659	5	64	theme	potential	1215:1223	arg1	comfort					1255:1261	thermal comfort	1247:1261	thermal comfort	1247:1261	This work presents an effective and facile strategy toward multifunctional Janus materials for efficient personal thermal management, showing great promise for potential applications, such as thermal comfort, infrared camouflage, and security protection.					
34999043	0	0	theme	enzymatic	93:101	arg1	hydrolysis					103:112	enzymatic hydrolysis	93:112	enzymatic hydrolysis of cellulose obtained from banana peduncle	93:155	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	1	1	theme	enzymatic	388:396	arg1	hydrolysis					398:407	optimized enzymatic hydrolysis	378:407	optimized enzymatic hydrolysis to glucose	378:418	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	1	2	theme	treatment	172:180	arg1	alkali					191:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	3	3	theme	Taguchi	769:775	arg1	design					777:782	Taguchi design	769:782	Taguchi design	769:782	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	3	4	theme	L9	757:758	arg1	array					760:764	an orthogonal L9 array	743:764	an orthogonal L9 array of Taguchi design	743:782	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	4	5	theme	cellulose	933:941	arg1	recovery					943:950	~81% cellulose recovery	928:950	~81% cellulose recovery	928:950	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	5	6	theme	driven	977:982	arg1	conversion					994:1003	cellulase driven enzymatic conversion	967:1003	cellulase driven enzymatic conversion to glucose	967:1014	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	1	7	theme	coupling	182:189	arg1	alkali					191:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	5	8	theme	substrate	1141:1149	arg1	concentration					1151:1163	substrate concentration	1141:1163	substrate concentration	1141:1163	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	2	9	dep	agrowastes	551:560	arg1	pseudostem					569:578	pseudostem	569:578	pseudostem	569:578	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	9	dep	agrowastes	551:560	arg1	peduncle					585:592	peduncle	585:592	peduncle	585:592	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	9	dep	agrowastes	551:560	arg1	peel					563:566	peel	563:566	peel	563:566	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	9	dep	agrowastes	551:560	arg1	agrowastes					551:560	three post-harvest banana agrowastes	525:560	three post-harvest banana agrowastes (peel, pseudostem, and peduncle)	525:593	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	6	10	theme	glucose	1319:1325	arg1	yield					1327:1331	~97% optimized glucose yield	1304:1331	~97% optimized glucose yield	1304:1331	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	6	11	theme	RSM	1278:1280	arg1	optimizations					1282:1294	RSM optimizations	1278:1294	RSM optimizations ensuing ~97% optimized glucose yield	1278:1331	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	0	12	theme	hydrolysis	103:112	arg1	enhancement					78:88	enhancement	78:88	enhancement	78:88	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	0	12	theme	hydrolysis	103:112	arg1	characterization					57:72	Structural characterization	46:72	Structural characterization	46:72	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	5	13	theme	surfactant	1170:1179	arg1	concentration					1181:1193	surfactant concentration	1170:1193	surfactant concentration	1170:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	4	14	theme	concentration	825:837	arg1	Effects					785:791	Effects	785:791	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters	785:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	3	15	theme	Isolation	610:618	arg1	precursor					682:690	the most efficient precursor	663:690	the most efficient precursor	663:690	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	3	15	theme	Isolation	610:618	arg1	parameters					620:629	Isolation parameters	610:629	Isolation parameters for banana peduncle agrowastes	610:660	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	5	16	theme	concentration	1181:1193	arg1	influences					1088:1097	the mutual influences	1077:1097	the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration	1077:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	4	17	theme	ratio	813:817	arg1	Effects					785:791	Effects	785:791	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters	785:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	0	18	theme	cellulose	117:125	arg1	hydrolysis					103:112	enzymatic hydrolysis	93:112	enzymatic hydrolysis of cellulose obtained from banana peduncle	93:155	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	3	19	theme	design	777:782	arg1	array					760:764	an orthogonal L9 array	743:764	an orthogonal L9 array of Taguchi design	743:782	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	4	20	theme	temperature	840:850	arg1	Effects					785:791	Effects	785:791	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters	785:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	6	21	theme	%	1307:1307	arg1	yield					1327:1331	~97% optimized glucose yield	1304:1331	~97% optimized glucose yield	1304:1331	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	4	22	theme	%	931:931	arg1	recovery					943:950	~81% cellulose recovery	928:950	~81% cellulose recovery	928:950	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	3	23	theme	banana	635:640	arg1	agrowastes					651:660	banana peduncle agrowastes	635:660	banana peduncle agrowastes	635:660	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	1	24	with	explosion	205:213	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	1	25	theme	steam	199:203	arg1	explosion					205:213	steam explosion	199:213	steam explosion	199:213	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	0	26	theme	Integrated	0:9	arg1	pretreatment					11:22	Integrated pretreatment	0:22	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.	0:156	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	5	27	dep	driven	977:982	arg1	cellulase					967:975	cellulase	967:975	cellulase	967:975	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	4	28	theme	~81	928:930	arg1	%					931:931	%	931:931	%	931:931	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	3	29	theme	peduncle	642:649	arg1	agrowastes					651:660	banana peduncle agrowastes	635:660	banana peduncle agrowastes	635:660	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	5	30	theme	enzymatic	984:992	arg1	conversion					994:1003	cellulase driven enzymatic conversion	967:1003	cellulase driven enzymatic conversion to glucose	967:1014	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	0	31	theme	banana	27:32	arg1	agrowastes					34:43	banana agrowastes	27:43	banana agrowastes	27:43	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	3	32	theme	efficient	672:680	arg1	precursor					682:690	the most efficient precursor	663:690	the most efficient precursor	663:690	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	3	32	theme	efficient	672:680	arg1	parameters					620:629	Isolation parameters	610:629	Isolation parameters for banana peduncle agrowastes	610:660	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	0	33	theme	banana	141:146	arg1	peduncle					148:155	banana peduncle	141:155	banana peduncle	141:155	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	5	34	theme	time	1113:1116	arg1	influences					1088:1097	the mutual influences	1077:1097	the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration	1077:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	4	35	theme	acid	820:823	arg1	concentration					825:837	acid concentration	820:837	acid concentration	820:837	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	2	36	theme	morphological	478:490	arg1	analysis					492:499	morphological analysis	478:499	morphological analysis	478:499	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	4	37	theme	solution-to-pulp	796:811	arg1	ratio					813:817	solution-to-pulp ratio	796:817	solution-to-pulp ratio	796:817	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	3	38	theme	acid	715:718	arg1	hydrolysis					720:729	acid hydrolysis	715:729	acid hydrolysis	715:729	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	5	39	theme	surface	1044:1050	arg1	RSM					1065:1067	RSM	1065:1067	RSM	1065:1067	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	5	39	theme	surface	1044:1050	arg1	methodology					1052:1062	response surface methodology	1035:1062	response surface methodology (RSM)	1035:1068	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	1	40	theme	ammonia/chlorine-free	219:239	arg1	bleaching					241:249	ammonia/chlorine-free bleaching	219:249	ammonia/chlorine-free bleaching	219:249	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	5	41	theme	concentration	1151:1163	arg1	influences					1088:1097	the mutual influences	1077:1097	the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration	1077:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	0	42	theme	agrowastes	34:43	arg1	pretreatment					11:22	Integrated pretreatment	0:22	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.	0:156	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	1	43	theme	banana	348:353	arg1	agrowastes					355:364	banana agrowastes	348:364	banana agrowastes followed by optimized enzymatic hydrolysis to glucose	348:418	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	2	44	theme	banana	544:549	arg1	pseudostem					569:578	pseudostem	569:578	pseudostem	569:578	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	44	theme	banana	544:549	arg1	peduncle					585:592	peduncle	585:592	peduncle	585:592	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	44	theme	banana	544:549	arg1	peel					563:566	peel	563:566	peel	563:566	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	44	theme	banana	544:549	arg1	agrowastes					551:560	three post-harvest banana agrowastes	525:560	three post-harvest banana agrowastes (peel, pseudostem, and peduncle)	525:593	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	4	45	theme	physicochemical	874:888	arg1	parameters					890:899	physicochemical parameters	874:899	physicochemical parameters	874:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	2	46	theme	post-harvest	531:542	arg1	pseudostem					569:578	pseudostem	569:578	pseudostem	569:578	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	46	theme	post-harvest	531:542	arg1	peduncle					585:592	peduncle	585:592	peduncle	585:592	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	46	theme	post-harvest	531:542	arg1	peel					563:566	peel	563:566	peel	563:566	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	2	46	theme	post-harvest	531:542	arg1	agrowastes					551:560	three post-harvest banana agrowastes	525:560	three post-harvest banana agrowastes (peel, pseudostem, and peduncle)	525:593	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	5	47	theme	incubation	1102:1111	arg1	time					1113:1116	incubation time	1102:1116	incubation time	1102:1116	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	6	48	theme	Network	1232:1238	arg1	modelling					1246:1254	Artificial Neural Network (ANN) modelling	1214:1254	Artificial Neural Network (ANN) modelling	1214:1254	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	0	49	theme	Structural	46:55	arg1	characterization					57:72	Structural characterization	46:72	Structural characterization	46:72	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	1	50	with	bleaching	241:249	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	5	51	theme	enzyme	1119:1124	arg1	concentration					1126:1138	enzyme concentration	1119:1138	enzyme concentration	1119:1138	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	6	52	theme	Neural	1225:1230	arg1	ANN					1241:1243	ANN	1241:1243	ANN	1241:1243	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	6	52	theme	Neural	1225:1230	arg1	Network					1232:1238	Artificial Neural Network	1214:1238	Artificial Neural Network (ANN) modelling	1214:1254	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	6	53	theme	optimized	1309:1317	arg1	yield					1327:1331	~97% optimized glucose yield	1304:1331	~97% optimized glucose yield	1304:1331	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	5	54	theme	mutual	1081:1086	arg1	influences					1088:1097	the mutual influences	1077:1097	the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration	1077:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	1	55	with	alkali	191:196	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	3	56	theme	orthogonal	746:755	arg1	array					760:764	an orthogonal L9 array	743:764	an orthogonal L9 array of Taguchi design	743:782	Isolation parameters for banana peduncle agrowastes, the most efficient precursor, were reconfigured for acid hydrolysis by applying an orthogonal L9 array of Taguchi design.					
34999043	4	57	theme	reaction	857:864	arg1	time					866:869	reaction time	857:869	reaction time	857:869	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	6	58	theme	Artificial	1214:1223	arg1	ANN					1241:1243	ANN	1241:1243	ANN	1241:1243	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	6	58	theme	Artificial	1214:1223	arg1	Network					1232:1238	Artificial Neural Network	1214:1238	Artificial Neural Network (ANN) modelling	1214:1254	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	4	59	from	Effects	785:791	arg1	parameters					890:899	physicochemical parameters	874:899	physicochemical parameters	874:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	1	60	theme	sequential	256:265	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	5	61	theme	concentration	1126:1138	arg1	influences					1088:1097	the mutual influences	1077:1097	the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration	1077:1193	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	6	62	theme	~97	1304:1306	arg1	%					1307:1307	%	1307:1307	%	1307:1307	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	5	63	theme	response	1035:1042	arg1	RSM					1065:1067	RSM	1065:1067	RSM	1065:1067	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	5	63	theme	response	1035:1042	arg1	methodology					1052:1062	response surface methodology	1035:1062	response surface methodology (RSM)	1035:1068	Subsequently, cellulase driven enzymatic conversion to glucose was modelled using response surface methodology (RSM), where the mutual influences of incubation time, enzyme concentration, substrate concentration, and surfactant concentration were investigated.					
34999043	1	64	theme	mild	267:270	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	0	65	dep	pretreatment	11:22	arg1	enhancement					78:88	enhancement	78:88	enhancement	78:88	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	0	65	dep	pretreatment	11:22	arg1	characterization					57:72	Structural characterization	46:72	Structural characterization	46:72	Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle.					
34999043	6	66	dep	improved	1264:1271	arg1	verified					1334:1341	verified	1334:1341	verified experimentally	1334:1356	Artificial Neural Network (ANN) modelling further improved upon RSM optimizations ensuing ~97% optimized glucose yield, verified experimentally.					
34999043	2	67	theme	cellulose	425:433	arg1	yield					435:439	The cellulose yield	421:439	The cellulose yield	421:439	The cellulose yield, compositional, microstructural, and morphological analysis initially obtained from three post-harvest banana agrowastes (peel, pseudostem, and peduncle) were surveyed.					
34999043	1	68	theme	acid	272:275	arg1	pretreatment					277:288	sequential mild acid pretreatment	256:288	sequential mild acid pretreatment	256:288	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	1	69	theme	optimized	378:386	arg1	hydrolysis					398:407	optimized enzymatic hydrolysis	378:407	optimized enzymatic hydrolysis to glucose	378:418	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
34999043	4	70	theme	time	866:869	arg1	Effects					785:791	Effects	785:791	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters	785:899	Effects of solution-to-pulp ratio, acid concentration, temperature, and reaction time on physicochemical parameters were assessed resulting in ~81% cellulose recovery.					
34999043	1	71	theme	integrated	161:170	arg1	alkali					191:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali	158:196	An integrated treatment coupling alkali, steam explosion and ammonia/chlorine-free bleaching with sequential mild acid pretreatment were performed to isolate and characterize cellulose from banana agrowastes followed by optimized enzymatic hydrolysis to glucose.					
35195289	4	0	theme	bomb	491:494	arg1	peak					496:499	the 14 C bomb peak	482:499	the 14 C bomb peak	482:499	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	5	1	theme	spectroscopy	554:565	arg1	measurements					585:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	2	2	theme	paper	304:308	arg1	production					281:290	production	281:290	production of the used paper	281:308	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	7	3	theme	plants	990:995	arg1	years					959:963	the actual harvest years	940:963	the actual harvest years	940:963	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	7	3	theme	plants	990:995	arg1	ages					931:934	the calibrated ages	916:934	the calibrated ages	916:934	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	8	4	from	concentration	1031:1043	arg1	fibers					1058:1063	the paper fibers	1048:1063	the paper fibers	1048:1063	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	7	5	theme	starch-containing	972:988	arg1	plants					990:995	the starch-containing plants	968:995	the starch-containing plants	968:995	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	8	6	theme	C	1029:1029	arg1	concentration					1031:1043	The 14 C concentration	1022:1043	The 14 C concentration in the paper fibers	1022:1063	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	6	7	theme	C	768:768	arg1	values					784:789	the measured 14 C concentration values	752:789	the measured 14 C concentration values in the starch extracts	752:812	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	8	8	theme	significant	1084:1094	arg1	correlation					1096:1106	a lower but significant correlation	1072:1106	a lower but significant correlation with the production year of the papers	1072:1145	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	6	9	theme	measured	756:763	arg1	values					784:789	the measured 14 C concentration values	752:789	the measured 14 C concentration values in the starch extracts	752:812	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	5	10	theme	Accelerator	537:547	arg1	spectroscopy					554:565	Accelerator mass spectroscopy	537:565	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	5	10	theme	Accelerator	537:547	arg1	AMS					568:570	AMS	568:570	AMS	568:570	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	8	11	theme	paper	1052:1056	arg1	fibers					1058:1063	the paper fibers	1048:1063	the paper fibers	1048:1063	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	9	12	theme	starch	1510:1515	arg1	extracts					1517:1524	the starch extracts	1506:1524	the starch extracts	1506:1524	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	13	theme	dating	1256:1261	arg1	accuracy					1240:1247	the accuracy	1236:1247	the accuracy of the dating	1236:1261	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	8	14	theme	production	1117:1126	arg1	year					1128:1131	the production year	1113:1131	the production year of the papers	1113:1145	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	9	15	theme	detailed	1378:1385	arg1	analysis					1396:1403	a detailed chemical analysis	1376:1403	a detailed chemical analysis of the paper composition including fiber composition	1376:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	16	theme	radiocarbon	1279:1289	arg1	measurements					1291:1302	the radiocarbon measurements	1275:1302	the radiocarbon measurements of the extracted starch other analytical methods	1275:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	2	17	theme	potential	195:203	arg1	1					322:322	1	322:322	1	322:322	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	2	17	theme	potential	195:203	arg1	difference					205:214	The potential difference	191:214	The potential difference between the date on a questioned document and the actual year of production of the used paper	191:308	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	8	18	theme	lower	1074:1078	arg1	correlation					1096:1106	a lower but significant correlation	1072:1106	a lower but significant correlation with the production year of the papers	1072:1145	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	8	19	theme	papers	1140:1145	arg1	year					1128:1131	the production year	1113:1131	the production year of the papers	1113:1145	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	5	20	theme	radiocarbon	573:583	arg1	measurements					585:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	5	21	from	samples	667:673	arg1	fibers					646:651	cellulose fibers	636:651	cellulose fibers	636:651	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	5	21	from	samples	667:673	arg1	extracts					623:630	starch extracts	616:630	starch extracts	616:630	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	9	22	theme	extracted	1311:1319	arg1	methods					1345:1351	the extracted starch other analytical methods	1307:1351	the extracted starch other analytical methods	1307:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	5	23	with	samples	667:673	arg1	year					697:700	known production year	680:700	known production year from 1950 to 2018	680:718	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	9	24	theme	other	1328:1332	arg1	methods					1345:1351	the extracted starch other analytical methods	1307:1351	the extracted starch other analytical methods	1307:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	6	25	theme	curve	885:889	arg1	data					846:849	the data	842:849	the data of the 14 C bomb peak calibration curve	842:889	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	5	26	theme	paper	661:665	arg1	samples					667:673	50 paper samples	658:673	50 paper samples with known production year from 1950 to 2018	658:718	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	8	27	used	used	1158:1161	arg2	concentration					1031:1043	The 14 C concentration	1022:1043	The 14 C concentration in the paper fibers	1022:1063	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	9	28	theme	methods	1345:1351	arg1	measurements					1291:1302	the radiocarbon measurements	1275:1302	the radiocarbon measurements of the extracted starch other analytical methods	1275:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	28	theme	methods	1345:1351	arg1	data					1356:1359	data	1356:1359	data	1356:1359	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	6	29	theme	peak	868:871	arg1	curve					885:889	the 14 C bomb peak calibration curve	854:889	the 14 C bomb peak calibration curve	854:889	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	1	30	theme	important	131:139	arg1	challenges					141:150	the most important challenges	122:150	the most important challenges for forensic document examiners (FDE)	122:188	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	6	31	theme	C	861:861	arg1	curve					885:889	the 14 C bomb peak calibration curve	854:889	the 14 C bomb peak calibration curve	854:889	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	8	32	theme	dating	1178:1183	arg1	results					1185:1191	the dating results	1174:1191	the dating results of the starch extracts	1174:1214	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	5	33	theme	cellulose	636:644	arg1	fibers					646:651	cellulose fibers	636:651	cellulose fibers	636:651	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	3	34	theme	analytical	360:369	arg1	method					371:376	no analytical method	357:376	no analytical method	357:376	Until now, there was no analytical method with this accuracy available.					
35195289	5	35	from	1950	707:710	arg1	year					697:700	known production year	680:700	known production year from 1950 to 2018	680:718	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	0	36	theme	radiocarbon	47:57	arg1	measurements					59:70	radiocarbon measurements	47:70	radiocarbon measurements	47:70	New method for the absolute dating of paper by radiocarbon measurements.					
35195289	8	37	theme	starch	1200:1205	arg1	extracts					1207:1214	the starch extracts	1196:1214	the starch extracts	1196:1214	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	0	38	theme	New	0:2	arg1	method					4:9	New method	0:9	New method for the absolute dating of paper by radiocarbon measurements.	0:71	New method for the absolute dating of paper by radiocarbon measurements.					
35195289	1	39	theme	absolute	77:84	arg1	challenges					141:150	the most important challenges	122:150	the most important challenges for forensic document examiners (FDE)	122:188	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	39	theme	absolute	77:84	arg1	one					115:117	one	115:117	one	115:117	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	39	theme	absolute	77:84	arg1	dating					86:91	The absolute dating	73:91	The absolute dating of documents	73:104	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	40	theme	challenges	141:150	arg1	challenges					141:150	the most important challenges	122:150	the most important challenges for forensic document examiners (FDE)	122:188	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	40	theme	challenges	141:150	arg1	one					115:117	one	115:117	one	115:117	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	40	theme	challenges	141:150	arg1	dating					86:91	The absolute dating	73:91	The absolute dating of documents	73:104	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	0	41	theme	absolute	19:26	arg1	dating					28:33	the absolute dating	15:33	the absolute dating of paper by radiocarbon measurements	15:70	New method for the absolute dating of paper by radiocarbon measurements.					
35195289	4	42	theme	absolute	448:455	arg1	dating					457:462	an absolute dating	445:462	an absolute dating of paper	445:471	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	4	43	from	starch	516:521	arg1	paper					530:534	the paper	526:534	the paper	526:534	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	2	44	theme	used	299:302	arg1	paper					304:308	the used paper	295:308	the used paper	295:308	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	9	45	theme	composition	1418:1428	arg1	analysis					1480:1487	the spectroscopic analysis	1462:1487	the spectroscopic analysis of the purity of the starch extracts	1462:1524	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	45	theme	composition	1418:1428	arg1	analysis					1396:1403	a detailed chemical analysis	1376:1403	a detailed chemical analysis of the paper composition including fiber composition	1376:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	46	theme	fiber	1440:1444	arg1	composition					1446:1456	fiber composition	1440:1456	fiber composition	1440:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	1	47	dep	examiners	174:182	arg1	document					165:172	document	165:172	document	165:172	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	10	48	theme	starch	1545:1550	arg1	extracts					1552:1559	only starch extracts	1540:1559	only starch extracts without contaminations	1540:1582	In practice, only starch extracts without contaminations are used for the paper dating.					
35195289	6	49	theme	starch	798:803	arg1	extracts					805:812	the starch extracts	794:812	the starch extracts	794:812	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	8	50	with	correlation	1096:1106	arg1	year					1128:1131	the production year	1113:1131	the production year of the papers	1113:1145	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	5	51	theme	mass	549:552	arg1	spectroscopy					554:565	Accelerator mass spectroscopy	537:565	Accelerator mass spectroscopy (AMS) radiocarbon measurements	537:596	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	5	51	theme	mass	549:552	arg1	AMS					568:570	AMS	568:570	AMS	568:570	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	9	52	theme	spectroscopic	1466:1478	arg1	analysis					1480:1487	the spectroscopic analysis	1462:1487	the spectroscopic analysis of the purity of the starch extracts	1462:1524	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	4	53	theme	C	489:489	arg1	peak					496:499	the 14 C bomb peak	482:499	the 14 C bomb peak	482:499	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	6	54	theme	concentration	770:782	arg1	values					784:789	the measured 14 C concentration values	752:789	the measured 14 C concentration values in the starch extracts	752:812	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	10	55	used	used	1588:1591	arg2	extracts					1552:1559	only starch extracts	1540:1559	only starch extracts without contaminations	1540:1582	In practice, only starch extracts without contaminations are used for the paper dating.					
35195289	8	56	theme	14	1026:1027	arg1	C					1029:1029	C	1029:1029	C	1029:1029	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	6	57	theme	14	765:766	arg1	C					768:768	C	768:768	C	768:768	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	9	58	theme	purity	1496:1501	arg1	analysis					1480:1487	the spectroscopic analysis	1462:1487	the spectroscopic analysis of the purity of the starch extracts	1462:1524	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	9	58	theme	purity	1496:1501	arg1	analysis					1396:1403	a detailed chemical analysis	1376:1403	a detailed chemical analysis of the paper composition including fiber composition	1376:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	7	59	theme	actual	944:949	arg1	years					959:963	the actual harvest years	940:963	the actual harvest years	940:963	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	10	60	theme	paper	1601:1605	arg1	dating					1607:1612	the paper dating	1597:1612	the paper dating	1597:1612	In practice, only starch extracts without contaminations are used for the paper dating.					
35195289	1	61	theme	forensic	156:163	arg1	FDE					185:187	FDE	185:187	FDE	185:187	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	61	theme	forensic	156:163	arg1	examiners					174:182	forensic document examiners	156:182	forensic document examiners (FDE)	156:188	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	7	62	theme	harvest	951:957	arg1	years					959:963	the actual harvest years	940:963	the actual harvest years	940:963	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	2	63	theme	actual	266:271	arg1	year					273:276	the actual year	262:276	the actual year of production of the used paper	262:308	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	9	64	theme	extracts	1517:1524	arg1	purity					1496:1501	the purity	1492:1501	the purity of the starch extracts	1492:1524	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	7	65	theme	calibrated	920:929	arg1	ages					931:934	the calibrated ages	916:934	the calibrated ages	916:934	The differences between the calibrated ages and the actual harvest years of the starch-containing plants were only up to 3 years.					
35195289	1	66	theme	documents	96:104	arg1	challenges					141:150	the most important challenges	122:150	the most important challenges for forensic document examiners (FDE)	122:188	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	66	theme	documents	96:104	arg1	one					115:117	one	115:117	one	115:117	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	1	66	theme	documents	96:104	arg1	dating					86:91	The absolute dating	73:91	The absolute dating of documents	73:104	The absolute dating of documents is still one of the most important challenges for forensic document examiners (FDE).					
35195289	9	67	theme	starch	1321:1326	arg1	methods					1345:1351	the extracted starch other analytical methods	1307:1351	the extracted starch other analytical methods	1307:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	5	68	theme	50	658:659	arg1	paper					661:665	paper	661:665	paper	661:665	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	9	69	theme	analytical	1334:1343	arg1	methods					1345:1351	the extracted starch other analytical methods	1307:1351	the extracted starch other analytical methods	1307:1351	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	6	70	theme	calibration	873:883	arg1	curve					885:889	the 14 C bomb peak calibration curve	854:889	the 14 C bomb peak calibration curve	854:889	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	2	71	dep	a	236:236	arg1	document					249:256	document	249:256	document	249:256	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	6	72	theme	bomb	863:866	arg1	curve					885:889	the 14 C bomb peak calibration curve	854:889	the 14 C bomb peak calibration curve	854:889	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	2	73	from	year	273:276	arg1	a					236:236	a	236:236	a	236:236	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	6	74	theme	14	858:859	arg1	C					861:861	C	861:861	C	861:861	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	5	75	theme	starch	616:621	arg1	extracts					623:630	starch extracts	616:630	starch extracts	616:630	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	9	76	theme	chemical	1387:1394	arg1	analysis					1396:1403	a detailed chemical analysis	1376:1403	a detailed chemical analysis of the paper composition including fiber composition	1376:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	4	77	theme	14	486:487	arg1	C					489:489	C	489:489	C	489:489	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	8	78	theme	extracts	1207:1214	arg1	results					1185:1191	the dating results	1174:1191	the dating results of the starch extracts	1174:1214	The 14 C concentration in the paper fibers showed a lower but significant correlation with the production year of the papers and can be used to support the dating results of the starch extracts.					
35195289	5	79	theme	known	680:684	arg1	year					697:700	known production year	680:700	known production year from 1950 to 2018	680:718	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	2	80	from	date	228:231	arg1	a					236:236	a	236:236	a	236:236	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	0	81	theme	paper	38:42	arg1	dating					28:33	the absolute dating	15:33	the absolute dating of paper by radiocarbon measurements	15:70	New method for the absolute dating of paper by radiocarbon measurements.					
35195289	6	82	theme	paper	737:741	arg1	samples					743:749	the paper samples	733:749	the paper samples	733:749	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35195289	9	83	theme	paper	1412:1416	arg1	composition					1418:1428	the paper composition	1408:1428	the paper composition including fiber composition	1408:1456	In order to secure the accuracy of the dating, aside from the radiocarbon measurements of the extracted starch other analytical methods or data are used, like a detailed chemical analysis of the paper composition including fiber composition and the spectroscopic analysis of the purity of the starch extracts.					
35195289	4	84	theme	paper	467:471	arg1	dating					457:462	an absolute dating	445:462	an absolute dating of paper	445:471	This study demonstrates a method for an absolute dating of paper by using the 14 C bomb peak and dating the starch in the paper.					
35195289	5	85	theme	production	686:695	arg1	year					697:700	known production year	680:700	known production year from 1950 to 2018	680:718	Accelerator mass spectroscopy (AMS) radiocarbon measurements were performed on starch extracts and cellulose fibers from 50 paper samples with known production year from 1950 to 2018.					
35195289	2	86	theme	production	281:290	arg1	year					273:276	the actual year	262:276	the actual year of production of the used paper	262:308	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	2	86	theme	production	281:290	arg1	date					228:231	the date	224:231	the date on a questioned document	224:256	The potential difference between the date on a questioned document and the actual year of production of the used paper can be only 1 to 5 years.					
35195289	6	87	from	values	784:789	arg1	extracts					805:812	the starch extracts	794:812	the starch extracts	794:812	For most of the paper samples, the measured 14 C concentration values in the starch extracts were highly correlated with the data of the 14 C bomb peak calibration curve.					
35803154	0	0	theme	microfibers	92:102	arg1	response					69:76	the viscoelastic response	52:76	the viscoelastic response of cell-laden microfibers	52:102	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers.					
35803154	6	1	theme	cellular	1270:1277	arg1	differentiation					1310:1324	differentiation	1310:1324	differentiation	1310:1324	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	6	1	theme	cellular	1270:1277	arg1	growth					1299:1304	growth	1299:1304	growth	1299:1304	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	6	1	theme	cellular	1270:1277	arg1	processes					1279:1287	two cellular processes	1266:1287	two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber	1266:1400	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	4	2	theme	pure	908:911	arg1	GelMA					913:917	pure GelMA	908:917	pure GelMA	908:917	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	6	3	theme	cells	1358:1362	arg1	differentiation					1310:1324	differentiation	1310:1324	differentiation	1310:1324	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	6	3	theme	cells	1358:1362	arg1	growth					1299:1304	growth	1299:1304	growth	1299:1304	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	0	4	theme	cell-laden	81:90	arg1	microfibers					92:102	cell-laden microfibers	81:102	cell-laden microfibers	81:102	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers.					
35803154	1	5	theme	regenerative	193:204	arg1	medicine					206:213	regenerative medicine	193:213	regenerative medicine	193:213	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	1	6	contain	have	139:142	arg2	applications					154:165	extensive applications	144:165	extensive applications	144:165	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	1	6	contain	have	139:142	arg1	microfibers					127:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	3	7	theme	liquid	560:565	arg1	method					589:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method enables single microfiber to be easily fixed to be stably stretched by a two-probe actuator.					
35803154	7	8	theme	reference	1471:1479	arg1	tool					1481:1484	a valuable reference tool	1460:1484	a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics	1460:1601	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	1	9	theme	microfiber-specific	303:321	arg1	system					333:338	microfiber-specific measuring system	303:338	microfiber-specific measuring system	303:338	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	2	10	dep	modulus	538:544	arg1	E					547:547	E'	547:548	E'	547:548	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	10	dep	modulus	538:544	arg1	E″					554:555	E″	554:555	E″	554:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	10	dep	modulus	538:544	arg1	modulus					538:544	the storage and loss modulus	517:544	the storage and loss modulus: E' and E″	517:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	3	11	theme	single	604:609	arg1	microfiber					611:620	single microfiber	604:620	single microfiber	604:620	A liquid bridge-based fixation method enables single microfiber to be easily fixed to be stably stretched by a two-probe actuator.					
35803154	5	12	with	microfibers	1085:1095	arg1	concentrations					1121:1134	different alginate concentrations	1102:1134	different alginate concentrations	1102:1134	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	1	13	theme	measuring	323:331	arg1	system					333:338	microfiber-specific measuring system	303:338	microfiber-specific measuring system	303:338	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	7	14	from	perspective	1578:1588	arg1	biomaterials					1490:1501	biomaterials	1490:1501	biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics	1490:1601	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	5	15	theme	measured	992:999	arg1	E					1001:1001	E'	1001:1002	E'	1001:1002	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	4	16	from	stress	822:827	arg1	spectrum					857:864	the frequency spectrum	843:864	the frequency spectrum	843:864	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	3	17	theme	fixation	580:587	arg1	method					589:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method enables single microfiber to be easily fixed to be stably stretched by a two-probe actuator.					
35803154	4	18	theme	stretching	716:725	arg1	loading					733:739	multi-frequency stretching force loading	700:739	multi-frequency stretching force loading	700:739	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	6	19	theme	core-shell	1380:1389	arg1	microfiber					1391:1400	the same one core-shell microfiber	1367:1400	the same one core-shell microfiber	1367:1400	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	2	20	theme	storage	521:527	arg1	E					547:547	E'	547:548	E'	547:548	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	20	theme	storage	521:527	arg1	E″					554:555	E″	554:555	E″	554:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	20	theme	storage	521:527	arg1	modulus					538:544	the storage and loss modulus	517:544	the storage and loss modulus: E' and E″	517:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	4	21	theme	multi-frequency	700:714	arg1	loading					733:739	multi-frequency stretching force loading	700:739	multi-frequency stretching force loading	700:739	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	0	22	theme	clamp-free	2:11	arg1	system					30:35	A clamp-free micro-stretching system	0:35	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers	0:102	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers.					
35803154	7	23	theme	valuable	1462:1469	arg1	tool					1481:1484	a valuable reference tool	1460:1484	a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics	1460:1601	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	6	24	theme	stem	1353:1356	arg1	cells					1358:1362	the aligned mesenchymal stem cells	1329:1362	the aligned mesenchymal stem cells	1329:1362	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	4	25	theme	force	789:793	arg1	control					795:801	real-time force control	779:801	real-time force control	779:801	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	7	26	theme	cell-matrix	1524:1534	arg1	interaction					1536:1546	cell-matrix interaction	1524:1546	cell-matrix interaction	1524:1546	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	1	27	theme	Viscoelastic	105:116	arg1	microfibers					127:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	6	28	theme	same	1371:1374	arg1	microfiber					1391:1400	the same one core-shell microfiber	1367:1400	the same one core-shell microfiber	1367:1400	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	4	29	theme	force	727:731	arg1	loading					733:739	multi-frequency stretching force loading	700:739	multi-frequency stretching force loading	700:739	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	4	30	theme	shell	969:973	arg1	microfibers					975:985	GelMA core-alginate shell microfibers	949:985	GelMA core-alginate shell microfibers	949:985	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	1	31	theme	hydrogel	118:125	arg1	microfibers					127:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers	105:137	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	2	32	theme	microfiber	492:501	arg1	viscoelasticity					469:483	viscoelasticity	469:483	viscoelasticity of the microfiber	469:501	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	0	33	theme	micro-stretching	13:28	arg1	system					30:35	A clamp-free micro-stretching system	0:35	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers	0:102	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers.					
35803154	4	34	theme	core-alginate	955:967	arg1	microfibers					975:985	GelMA core-alginate shell microfibers	949:985	GelMA core-alginate shell microfibers	949:985	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	5	35	theme	different	1102:1110	arg1	concentrations					1121:1134	different alginate concentrations	1102:1134	different alginate concentrations	1102:1134	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	7	36	theme	proposed	1435:1442	arg1	system					1444:1449	our proposed system	1431:1449	our proposed system	1431:1449	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	1	37	theme	tissue	170:175	arg1	engineering					177:187	tissue engineering	170:187	tissue engineering	170:187	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	6	38	from	growth	1299:1304	arg1	microfiber					1391:1400	the same one core-shell microfiber	1367:1400	the same one core-shell microfiber	1367:1400	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	6	39	theme	stretching	1179:1188	arg1	process					1190:1196	the low-damaged stretching process	1163:1196	the low-damaged stretching process	1163:1196	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	5	40	theme	alginate	1112:1119	arg1	concentrations					1121:1134	different alginate concentrations	1102:1134	different alginate concentrations	1102:1134	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	5	41	theme	NIH/3T3	1043:1049	arg1	cells					1062:1066	NIH/3T3 fibroblast cells	1043:1066	NIH/3T3 fibroblast cells	1043:1066	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	1	42	theme	quantitative	355:366	arg1	studies					368:374	quantitative studies	355:374	quantitative studies	355:374	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	4	43	theme	microfibers	975:985	arg1	E					895:895	the E'	891:896	the E'	891:896	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	5	44	theme	fibroblast	1051:1060	arg1	cells					1062:1066	NIH/3T3 fibroblast cells	1043:1066	NIH/3T3 fibroblast cells	1043:1066	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	2	45	theme	loss	533:536	arg1	E					547:547	E'	547:548	E'	547:548	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	45	theme	loss	533:536	arg1	E″					554:555	E″	554:555	E″	554:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	2	45	theme	loss	533:536	arg1	modulus					538:544	the storage and loss modulus	517:544	the storage and loss modulus: E' and E″	517:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	7	46	dep	biomaterials	1490:1501	arg1	design					1503:1508	design	1503:1508	design	1503:1508	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	7	46	dep	biomaterials	1490:1501	arg1	study					1515:1519	the study	1511:1519	the study of cell-matrix interaction and disease etiology	1511:1567	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	4	47	theme	composite	935:943	arg1	E					895:895	the E'	891:896	the E'	891:896	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	5	48	theme	cells	1062:1066	arg1	response					1031:1038	the response	1027:1038	the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations	1027:1134	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	6	49	theme	mesenchymal	1341:1351	arg1	cells					1358:1362	the aligned mesenchymal stem cells	1329:1362	the aligned mesenchymal stem cells	1329:1362	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	4	50	theme	real-time	779:787	arg1	control					795:801	real-time force control	779:801	real-time force control	779:801	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	4	51	theme	alginate-GelMA	920:933	arg1	composite					935:943	alginate-GelMA composite	920:943	alginate-GelMA composite	920:943	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	7	52	theme	disease	1552:1558	arg1	etiology					1560:1567	disease etiology	1552:1567	disease etiology	1552:1567	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	7	53	theme	etiology	1560:1567	arg1	design					1503:1508	design	1503:1508	design	1503:1508	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	7	53	theme	etiology	1560:1567	arg1	study					1515:1519	the study	1511:1519	the study of cell-matrix interaction and disease etiology	1511:1567	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	1	54	theme	extensive	144:152	arg1	applications					154:165	extensive applications	144:165	extensive applications	144:165	Viscoelastic hydrogel microfibers have extensive applications in tissue engineering and regenerative medicine, however, their viscoelasticity is still difficult to be directly characterized because microfiber-specific measuring system is lacking for quantitative studies.					
35803154	4	55	theme	GelMA	949:953	arg1	microfibers					975:985	GelMA core-alginate shell microfibers	949:985	GelMA core-alginate shell microfibers	949:985	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	5	56	theme	composite	1075:1083	arg1	microfibers					1085:1095	the composite microfibers	1071:1095	the composite microfibers with different alginate concentrations	1071:1134	The measured E' and E″ are verified by the response of NIH/3T3 fibroblast cells to the composite microfibers with different alginate concentrations.					
35803154	4	57	theme	frequency	847:855	arg1	spectrum					857:864	the frequency spectrum	843:864	the frequency spectrum	843:864	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	4	58	from	strain	833:838	arg1	spectrum					857:864	the frequency spectrum	843:864	the frequency spectrum	843:864	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	6	59	theme	low-damaged	1167:1177	arg1	process					1190:1196	the low-damaged stretching process	1163:1196	the low-damaged stretching process	1163:1196	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	4	60	theme	resulting	812:820	arg1	stress					822:827	stress	822:827	stress	822:827	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	6	61	from	differentiation	1310:1324	arg1	microfiber					1391:1400	the same one core-shell microfiber	1367:1400	the same one core-shell microfiber	1367:1400	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	6	62	theme	aligned	1333:1339	arg1	cells					1358:1362	the aligned mesenchymal stem cells	1329:1362	the aligned mesenchymal stem cells	1329:1362	Moreover, benefiting from the low-damaged stretching process, our system can also detect the difference of the E' and E″ between two cellular processes including growth and differentiation of the aligned mesenchymal stem cells in the same one core-shell microfiber.					
35803154	7	63	theme	interaction	1536:1546	arg1	design					1503:1508	design	1503:1508	design	1503:1508	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	7	63	theme	interaction	1536:1546	arg1	study					1515:1519	the study	1511:1519	the study of cell-matrix interaction and disease etiology	1511:1567	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	3	64	theme	two-probe	669:677	arg1	actuator					679:686	a two-probe actuator	667:686	a two-probe actuator	667:686	A liquid bridge-based fixation method enables single microfiber to be easily fixed to be stably stretched by a two-probe actuator.					
35803154	7	65	theme	mechanics	1593:1601	arg1	perspective					1578:1588	the perspective	1574:1588	the perspective of mechanics	1574:1601	These results all show that our proposed system provides a valuable reference tool for biomaterials design, the study of cell-matrix interaction and disease etiology from the perspective of mechanics.					
35803154	3	66	theme	bridge-based	567:578	arg1	method					589:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method	558:594	A liquid bridge-based fixation method enables single microfiber to be easily fixed to be stably stretched by a two-probe actuator.					
35803154	4	67	theme	GelMA	913:917	arg1	E					895:895	the E'	891:896	the E'	891:896	Afterward, multi-frequency stretching force loading is automatically implemented based on real-time force control, and the resulting stress and strain in the frequency spectrum are measured to evaluate the E' and E″ of pure GelMA, alginate-GelMA composite and GelMA core-alginate shell microfibers.					
35803154	2	68	theme	micro-stretching	415:430	arg1	system					432:437	a two-probe micro-stretching system	403:437	a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″	403:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35803154	0	69	theme	viscoelastic	56:67	arg1	response					69:76	the viscoelastic response	52:76	the viscoelastic response of cell-laden microfibers	52:102	A clamp-free micro-stretching system for evaluating the viscoelastic response of cell-laden microfibers.					
35803154	2	70	theme	two-probe	405:413	arg1	system					432:437	a two-probe micro-stretching system	403:437	a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″	403:555	In this paper, we develop a two-probe micro-stretching system to quantitatively investigate viscoelasticity of the microfiber by evaluating the storage and loss modulus: E' and E″.					
35569679	2	0	theme	aqueous	473:479	arg1	solution					481:488	the miscible aqueous solution	460:488	the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	460:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	6	1	theme	Janus	1268:1272	arg1	hydrogels					1274:1282	The Janus hydrogels	1264:1282	The Janus hydrogels	1264:1282	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	0	2	with	hydrogels	54:62	arg1	conductivity					89:100	conductivity	89:100	conductivity	89:100	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	0	2	with	hydrogels	54:62	arg1	hierarchy					75:83	Janus hierarchy	69:83	Janus hierarchy	69:83	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	1	3	theme	marine	266:271	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	3	theme	marine	266:271	arg1	SA					322:323	SA	322:323	SA	322:323	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	3	theme	marine	266:271	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	3	theme	marine	266:271	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	4	theme	miscible	464:471	arg1	solution					481:488	the miscible aqueous solution	460:488	the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	460:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	5	5	with	layer	1134:1138	arg1	conductivity					1149:1160	the conductivity	1145:1160	the conductivity less than 0.60 S·m-1 and the thickness adjustable	1145:1210	The weakly conductive layer with the conductivity less than 0.60 S·m-1 and the thickness adjustable, constitutes a protective screen for another layer.					
35569679	1	6	theme	biobased	273:280	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	6	theme	biobased	273:280	arg1	SA					322:323	SA	322:323	SA	322:323	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	6	theme	biobased	273:280	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	6	theme	biobased	273:280	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	4	7	theme	electronic	1024:1033	arg1	areas					1035:1039	soft electronic areas	1019:1039	soft electronic areas like human-machine interfaces, smart wearable devices and soft robots	1019:1109	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	1	8	theme	anionic	282:288	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	8	theme	anionic	282:288	arg1	SA					322:323	SA	322:323	SA	322:323	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	8	theme	anionic	282:288	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	8	theme	anionic	282:288	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	0	9	theme	tannic	114:119	arg1	acid					121:124	tannic acid	114:124	tannic acid	114:124	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	2	10	theme	TA	555:556	arg1	strength					543:550	the much larger interaction strength	515:550	the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	515:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	1	11	theme	polysaccharide	290:303	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	11	theme	polysaccharide	290:303	arg1	SA					322:323	SA	322:323	SA	322:323	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	11	theme	polysaccharide	290:303	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	11	theme	polysaccharide	290:303	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	4	12	theme	conductive	919:928	arg1	layer					930:934	The strongly conductive layer	906:934	The strongly conductive layer	906:934	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	1	13	with	hydrogels	151:159	arg1	conductive					168:177	conductive	168:177	conductive	168:177	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	14	with	TA	555:556	arg1	PVA					563:565	PVA	563:565	PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	563:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	1	15	theme	non-	185:188	arg1	layer					211:215	a non- or weakly conductive layer	183:215	a non- or weakly conductive layer for comfortable and safe electronic application	183:263	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	16	theme	SA	493:494	arg1	solution					481:488	the miscible aqueous solution	460:488	the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	460:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	3	17	theme	Janus	782:786	arg1	hierarchy					789:797	a "Janus" hierarchy	779:797	a "Janus" hierarchy	779:797	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	2	18	from	view	507:510	arg1	solution					481:488	the miscible aqueous solution	460:488	the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	460:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	0	19	theme	alginate/polyvinyl	17:34	arg1	hydrogels					54:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels	0:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity	0:100	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	2	20	with	PVA	595:597	arg1	SA					604:605	SA	604:605	SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	604:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	4	21	from	application	1004:1014	arg1	areas					1035:1039	soft electronic areas	1019:1039	soft electronic areas like human-machine interfaces, smart wearable devices and soft robots	1019:1109	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	6	22	theme	good	1292:1295	arg1	performance					1308:1318	good mechanical performance	1292:1318	good mechanical performance	1292:1318	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	0	23	theme	Strain-sensitive	0:15	arg1	hydrogels					54:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels	0:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity	0:100	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	1	24	theme	sodium	305:310	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	24	theme	sodium	305:310	arg1	SA					322:323	SA	322:323	SA	322:323	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	24	theme	sodium	305:310	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	24	theme	sodium	305:310	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	4	25	theme	wearable	1078:1085	arg1	devices					1087:1093	smart wearable devices	1072:1093	smart wearable devices	1072:1093	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	1	26	theme	conductive	200:209	arg1	layer					211:215	a non- or weakly conductive layer	183:215	a non- or weakly conductive layer for comfortable and safe electronic application	183:263	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	0	27	theme	composite	44:52	arg1	hydrogels					54:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels	0:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity	0:100	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	6	28	theme	strain-sensing	1331:1344	arg1	performance					1346:1356	excellent strain-sensing performance	1321:1356	excellent strain-sensing performance	1321:1356	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	4	29	theme	smart	1072:1076	arg1	devices					1087:1093	smart wearable devices	1072:1093	smart wearable devices	1072:1093	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	0	30	theme	alcohol	36:42	arg1	hydrogels					54:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels	0:62	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity	0:100	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	5	31	theme	less	1162:1165	arg1	conductivity					1149:1160	the conductivity	1145:1160	the conductivity less than 0.60 S·m-1 and the thickness adjustable	1145:1210	The weakly conductive layer with the conductivity less than 0.60 S·m-1 and the thickness adjustable, constitutes a protective screen for another layer.					
35569679	6	32	theme	excellent	1321:1329	arg1	performance					1346:1356	excellent strain-sensing performance	1321:1356	excellent strain-sensing performance	1321:1356	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	1	33	theme	hydrogel	383:390	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	33	theme	hydrogel	383:390	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	33	theme	hydrogel	383:390	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	34	dep	theory	646:651	arg1	-21.00 kcal·mol-1					673:689	-21.00 kcal·mol-1	673:689	-21.00 kcal·mol-1	673:689	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	34	dep	theory	646:651	arg1	-40.21					654:659	-40.21	654:659	-40.21	654:659	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	4	35	theme	more	963:966	arg1	conductivity					947:958	a conductivity	945:958	a conductivity of more than 2.95 S·m-1	945:982	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	3	36	theme	conductive	864:873	arg1	layer					849:853	one layer	845:853	one layer strongly conductive	845:873	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	1	37	with	layer	211:215	arg1	conductive					168:177	conductive	168:177	conductive	168:177	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	4	38	theme	soft	1099:1102	arg1	robots					1104:1109	soft robots	1099:1109	soft robots	1099:1109	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	2	39	with	TA	580:581	arg1	PVA					595:597	PVA	595:597	PVA	595:597	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	39	with	TA	580:581	arg1	SA					588:589	SA	588:589	SA	588:589	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	1	40	theme	comfortable	221:231	arg1	application					253:263	comfortable and safe electronic application	221:263	comfortable and safe electronic application	221:263	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	41	theme	Tannic	402:407	arg1	TA					415:416	TA	415:416	TA	415:416	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	41	theme	Tannic	402:407	arg1	acid					409:412	Tannic acid	402:412	Tannic acid (TA)	402:417	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	3	42	theme	alginate/PVA	729:740	arg1	hydrogels					752:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	3	43	theme	"	787:787	arg1	hierarchy					789:797	a "Janus" hierarchy	779:797	a "Janus" hierarchy	779:797	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	3	44	theme	finally-fabricated	710:727	arg1	hydrogels					752:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	3	45	theme	composite	742:750	arg1	hydrogels					752:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels	706:760	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	6	46	theme	mechanical	1297:1306	arg1	performance					1308:1318	good mechanical performance	1292:1318	good mechanical performance	1292:1318	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	2	47	from	solution	481:488	arg1	view					507:510	view	507:510	view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	507:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	3	48	dep	layer	849:853	arg1	i.e.					839:842	i.e.	839:842	i.e.	839:842	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	0	49	theme	Janus	69:73	arg1	hierarchy					75:83	Janus hierarchy	69:83	Janus hierarchy	69:83	Strain-sensitive alginate/polyvinyl alcohol composite hydrogels with Janus hierarchy and conductivity mediated by tannic acid.					
35569679	1	50	theme	neutral	330:336	arg1	PVA					357:359	PVA	357:359	PVA	357:359	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	50	theme	neutral	330:336	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	50	theme	neutral	330:336	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	50	theme	neutral	330:336	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	51	theme	strength	543:550	arg1	view					507:510	view	507:510	view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	507:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	52	theme	functional	635:644	arg1	theory					646:651	the density functional theory	623:651	the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	623:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	1	53	theme	conductive	140:149	arg1	hydrogels					151:159	conductive hydrogels	140:159	conductive hydrogels with a conductive	140:177	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	4	54	theme	human-machine	1046:1058	arg1	interfaces					1060:1069	human-machine interfaces	1046:1069	human-machine interfaces	1046:1069	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	1	55	theme	polyvinyl	338:346	arg1	PVA					357:359	PVA	357:359	PVA	357:359	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	55	theme	polyvinyl	338:346	arg1	alcohol					348:354	neutral polyvinyl alcohol	330:354	neutral polyvinyl alcohol (PVA)	330:360	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	55	theme	polyvinyl	338:346	arg1	matrixes					392:399	the hydrogel matrixes	379:399	the hydrogel matrixes	379:399	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	1	55	theme	polyvinyl	338:346	arg1	alginate					312:319	marine biobased anionic polysaccharide sodium alginate	266:319	marine biobased anionic polysaccharide sodium alginate (SA)	266:324	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	56	theme	interaction	531:541	arg1	strength					543:550	the much larger interaction strength	515:550	the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	515:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	57	from	SA	493:494	arg1	view					507:510	view	507:510	view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	507:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	2	58	theme	density	627:633	arg1	theory					646:651	the density functional theory	623:651	the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	623:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	3	59	theme	asymmetrical	812:823	arg1	conductivity					825:836	asymmetrical conductivity	812:836	asymmetrical conductivity	812:836	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	1	60	theme	safe	237:240	arg1	application					253:263	comfortable and safe electronic application	221:263	comfortable and safe electronic application	221:263	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	61	theme	larger	524:529	arg1	strength					543:550	the much larger interaction strength	515:550	the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	515:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	6	62	theme	fatigue-resistant	1362:1378	arg1	mechanics					1380:1388	fatigue-resistant mechanics	1362:1388	fatigue-resistant mechanics	1362:1388	The Janus hydrogels exhibit good mechanical performance, excellent strain-sensing performance and fatigue-resistant mechanics, conductivity and sensitivity.					
35569679	1	63	theme	electronic	242:251	arg1	application					253:263	comfortable and safe electronic application	221:263	comfortable and safe electronic application	221:263	To construct conductive hydrogels with a conductive and a non- or weakly conductive layer for comfortable and safe electronic application, marine biobased anionic polysaccharide sodium alginate (SA) and neutral polyvinyl alcohol (PVA) were employed as the hydrogel matrixes.					
35569679	2	64	from	PVA	500:502	arg1	view					507:510	view	507:510	view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	507:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	3	65	dep	hydrogels	752:760	arg1	only					766:769	only	766:769	only	766:769	The finally-fabricated alginate/PVA composite hydrogels not only possess a "Janus" hierarchy but manifest asymmetrical conductivity, i.e., one layer strongly conductive and another weakly conductive.					
35569679	5	66	theme	protective	1227:1236	arg1	screen					1238:1243	a protective screen	1225:1243	a protective screen for another layer	1225:1261	The weakly conductive layer with the conductivity less than 0.60 S·m-1 and the thickness adjustable, constitutes a protective screen for another layer.					
35569679	2	67	with	SA	588:589	arg1	SA					604:605	SA	604:605	SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	604:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
35569679	5	68	theme	conductive	1123:1132	arg1	layer					1134:1138	The weakly conductive layer	1112:1138	The weakly conductive layer	1112:1138	The weakly conductive layer with the conductivity less than 0.60 S·m-1 and the thickness adjustable, constitutes a protective screen for another layer.					
35569679	5	69	theme	adjustable	1201:1210	arg1	thickness					1191:1199	the thickness adjustable	1187:1210	the thickness adjustable	1187:1210	The weakly conductive layer with the conductivity less than 0.60 S·m-1 and the thickness adjustable, constitutes a protective screen for another layer.					
35569679	4	70	theme	soft	1019:1022	arg1	areas					1035:1039	soft electronic areas	1019:1039	soft electronic areas like human-machine interfaces, smart wearable devices and soft robots	1019:1109	The strongly conductive layer achieves a conductivity of more than 2.95 S·m-1, facilitating their application in soft electronic areas like human-machine interfaces, smart wearable devices and soft robots.					
35569679	2	71	theme	PVA	500:502	arg1	solution					481:488	the miscible aqueous solution	460:488	the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively)	460:703	Tannic acid (TA) was exploited to mediate the demixing of the miscible aqueous solution of SA and PVA in view of the much larger interaction strength of TA with PVA than both of TA with SA and PVA with SA calculated from the density functional theory (-40.21, -29.77 and -21.00 kcal·mol-1 respectively).					
37244327	2	0	theme	agro-industrial	365:379	arg1	bagasse					353:359	sugarcane bagasse	343:359	sugarcane bagasse	343:359	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	2	0	theme	agro-industrial	365:379	arg1	waste					381:385	an agro-industrial waste	362:385	an agro-industrial waste into lignocellulosic nanofibrils (LCNF)	362:425	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	0	1	theme	imidazolate	102:112	arg1	framework-8					114:124	zeolitic imidazolate framework-8	93:124	zeolitic imidazolate framework-8 for food packaging	93:143	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	0	2	theme	food	130:133	arg1	packaging					135:143	food packaging	130:143	food packaging	130:143	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	6	3	theme	LCNF/GG/MOF-4	903:915	arg1	film					917:920	The LCNF/GG/MOF-4 film	899:920	The LCNF/GG/MOF-4 film	899:920	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	7	4	theme	control	1085:1091	arg1	samples					1101:1107	packaged control bananas samples	1076:1107	packaged control bananas samples	1076:1107	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	2	5	theme	fabrication	301:311	arg1	approach					313:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	6	6	theme	scavenging	986:995	arg1	capacity					997:1004	highest ethylene scavenging capacity	969:1004	highest ethylene scavenging capacity (40.2 %)	969:1013	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	6	6	theme	scavenging	986:995	arg1	%					1012:1012	40.2 %	1007:1012	40.2 %	1007:1012	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	9	7	theme	application	1307:1317	arg1	prospects					1319:1327	potential application prospects	1297:1327	potential application prospects for being used in prolonging the shelf life of fresh produce	1297:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	7	8	theme	bananas	1093:1099	arg1	samples					1101:1107	packaged control bananas samples	1076:1107	packaged control bananas samples	1076:1107	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	2	9	theme	benign	294:299	arg1	approach					313:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	5	10	theme	antioxidant	859:869	arg1	activity					871:878	antioxidant activity	859:878	antioxidant activity of around 69.55 %	859:896	The characterization results suggested that pure LCNF showed antioxidant activity of around 69.55 %.					
37244327	8	11	theme	banana	1159:1164	arg1	package					1166:1172	a banana package	1157:1172	a banana package consisting of LCNF/GG/MOF-4 film	1157:1205	In contrast, a banana package consisting of LCNF/GG/MOF-4 film maintained their high quality in terms of colour.					
37244327	9	12	dep	fresh	1376:1380	arg1	produce					1382:1388	produce	1382:1388	produce	1382:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	8	13	theme	colour	1249:1254	arg1	terms					1240:1244	terms	1240:1244	terms of colour	1240:1254	In contrast, a banana package consisting of LCNF/GG/MOF-4 film maintained their high quality in terms of colour.					
37244327	9	14	contain	has	1293:1295	arg2	prospects					1319:1327	potential application prospects	1297:1327	potential application prospects for being used in prolonging the shelf life of fresh produce	1297:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	9	14	contain	has	1293:1295	arg1	film					1288:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	3	15	theme	biodegradable	451:463	arg1	film					465:468	biodegradable film	451:468	biodegradable film	451:468	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	6	16	theme	ethylene	977:984	arg1	capacity					997:1004	highest ethylene scavenging capacity	969:1004	highest ethylene scavenging capacity (40.2 %)	969:1013	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	6	16	theme	ethylene	977:984	arg1	%					1012:1012	40.2 %	1007:1012	40.2 %	1007:1012	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	7	17	theme	packaged	1076:1083	arg1	samples					1101:1107	packaged control bananas samples	1076:1107	packaged control bananas samples	1076:1107	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	2	18	theme	simple	283:288	arg1	approach					313:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	0	19	theme	nanofibrils/guar	15:30	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	6	20	theme	highest	969:975	arg1	capacity					997:1004	highest ethylene scavenging capacity	969:1004	highest ethylene scavenging capacity (40.2 %)	969:1013	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	6	20	theme	highest	969:975	arg1	%					1012:1012	40.2 %	1007:1012	40.2 %	1007:1012	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	0	21	theme	Lignocellulose	0:13	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	4	22	contain	possesses	726:734	arg1	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg1	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg1	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg1	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg1	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg2	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg2	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg2	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg2	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	22	contain	possesses	726:734	arg2	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	2	23	theme	lignocellulosic	392:406	arg1	LCNF					421:424	LCNF	421:424	LCNF	421:424	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	2	23	theme	lignocellulosic	392:406	arg1	nanofibrils					408:418	lignocellulosic nanofibrils	392:418	lignocellulosic nanofibrils (LCNF)	392:425	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	0	24	theme	ethylene	42:49	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	5	25	theme	characterization	802:817	arg1	results					819:825	The characterization results	798:825	The characterization results	798:825	The characterization results suggested that pure LCNF showed antioxidant activity of around 69.55 %.					
37244327	4	26	theme	ethylene	736:743	arg1	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	26	theme	ethylene	736:743	arg1	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	26	theme	ethylene	736:743	arg1	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	26	theme	ethylene	736:743	arg1	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	26	theme	ethylene	736:743	arg1	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	27	theme	LCNF/GG	627:633	arg1	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	27	theme	LCNF/GG	627:633	arg1	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	27	theme	LCNF/GG	627:633	arg1	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	27	theme	LCNF/GG	627:633	arg1	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	27	theme	LCNF/GG	627:633	arg1	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	0	28	theme	gum-based	32:40	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	7	29	theme	storage	1054:1060	arg1	6 days					1044:1049	6 days	1044:1049	6 days of storage at 25 ± 2 °C	1044:1073	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	5	30	theme	pure	842:845	arg1	LCNF					847:850	pure LCNF	842:850	pure LCNF	842:850	The characterization results suggested that pure LCNF showed antioxidant activity of around 69.55 %.					
37244327	0	31	theme	composite	62:70	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	3	32	theme	framework	596:604	arg1	-8/zeolite					611:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	1	33	theme	shelf	204:208	arg1	vegetables					269:278	vegetables	269:278	vegetables	269:278	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	33	theme	shelf	204:208	arg1	fruits					258:263	climacteric fruits	246:263	climacteric fruits	246:263	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	33	theme	shelf	204:208	arg1	life					210:213	the shelf life	200:213	the shelf life of fresh produce	200:230	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	34	theme	fresh	218:222	arg1	vegetables					269:278	vegetables	269:278	vegetables	269:278	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	34	theme	fresh	218:222	arg1	fruits					258:263	climacteric fruits	246:263	climacteric fruits	246:263	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	34	theme	fresh	218:222	arg1	life					210:213	the shelf life	200:213	the shelf life of fresh produce	200:230	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	0	35	theme	scavenging	51:60	arg1	film					72:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film	0:75	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	9	36	theme	shelf	1362:1366	arg1	life					1368:1371	the shelf life	1358:1371	the shelf life of fresh produce	1358:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	8	37	theme	LCNF/GG/MOF-4	1188:1200	arg1	film					1202:1205	LCNF/GG/MOF-4 film	1188:1205	LCNF/GG/MOF-4 film	1188:1205	In contrast, a banana package consisting of LCNF/GG/MOF-4 film maintained their high quality in terms of colour.					
37244327	9	38	theme	fresh	1376:1380	arg1	life					1368:1371	the shelf life	1358:1371	the shelf life of fresh produce	1358:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	7	39	theme	significant	1119:1129	arg1	degradation					1131:1141	significant degradation	1119:1141	significant degradation	1119:1141	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	7	40	from	25 ± 2 °C	1065:1073	arg1	6 days					1044:1049	6 days	1044:1049	6 days of storage at 25 ± 2 °C	1044:1073	After 6 days of storage at 25 ± 2 °C, packaged control bananas samples underwent significant degradation.					
37244327	3	41	theme	zeolitic	575:582	arg1	-8/zeolite					611:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	4	42	theme	ZIF-8/zeolite	692:704	arg1	composite					706:714	the ZIF-8/zeolite composite	688:714	the ZIF-8/zeolite composite	688:714	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	9	43	theme	potential	1297:1305	arg1	prospects					1319:1327	potential application prospects	1297:1327	potential application prospects for being used in prolonging the shelf life of fresh produce	1297:1388	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	3	44	theme	imidazolate	584:594	arg1	-8/zeolite					611:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	3	45	theme	sugarcane	512:520	arg1	bagasse					522:528	sugarcane bagasse	512:528	sugarcane bagasse	512:528	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	6	46	theme	lowest	932:937	arg1	UV-transmittance					939:954	lowest UV-transmittance	932:954	lowest UV-transmittance (5.06 %)	932:963	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	6	46	theme	lowest	932:937	arg1	%					962:962	5.06 %	957:962	5.06 %	957:962	The LCNF/GG/MOF-4 film has shown lowest UV-transmittance (5.06 %) and highest ethylene scavenging capacity (40.2 %) among all the samples.					
37244327	4	47	theme	UV-blocking	774:784	arg1	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	47	theme	UV-blocking	774:784	arg1	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	47	theme	UV-blocking	774:784	arg1	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	47	theme	UV-blocking	774:784	arg1	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	47	theme	UV-blocking	774:784	arg1	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	1	48	dep	fresh	218:222	arg1	produce					224:230	produce	224:230	produce	224:230	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	4	49	theme	biodegradable	659:671	arg1	film					635:638	The LCNF/GG film	623:638	The LCNF/GG film	623:638	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	49	theme	biodegradable	659:671	arg1	properties					786:795	UV-blocking properties	774:795	UV-blocking properties	774:795	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	49	theme	biodegradable	659:671	arg1	antioxidant					757:767	antioxidant	757:767	antioxidant	757:767	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	49	theme	biodegradable	659:671	arg1	matrix					673:678	a biodegradable matrix	657:678	a biodegradable matrix	657:678	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	4	49	theme	biodegradable	659:671	arg1	scavenging					745:754	ethylene scavenging	736:754	ethylene scavenging	736:754	The LCNF/GG film not only acts as a biodegradable matrix to hold the ZIF-8/zeolite composite, but also possesses ethylene scavenging, antioxidant, and UV-blocking properties.					
37244327	2	50	theme	sugarcane	343:351	arg1	bagasse					353:359	sugarcane bagasse	343:359	sugarcane bagasse	343:359	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	2	50	theme	sugarcane	343:351	arg1	waste					381:385	an agro-industrial waste	362:385	an agro-industrial waste into lignocellulosic nanofibrils (LCNF)	362:425	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	9	51	theme	Fabricated	1257:1266	arg1	film					1288:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	1	52	theme	ripening	158:165	arg1	Ethylene					146:153	Ethylene	146:153	Ethylene	146:153	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	52	theme	ripening	158:165	arg1	hormone					167:173	a ripening hormone	156:173	a ripening hormone	156:173	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	2	53	used	used	325:328	arg2	approach					313:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach	281:320	A simple and benign fabrication approach is used to transform sugarcane bagasse, an agro-industrial waste into lignocellulosic nanofibrils (LCNF).					
37244327	0	54	theme	zeolitic	93:100	arg1	framework-8					114:124	zeolitic imidazolate framework-8	93:124	zeolitic imidazolate framework-8 for food packaging	93:143	Lignocellulose nanofibrils/guar gum-based ethylene scavenging composite film integrated with zeolitic imidazolate framework-8 for food packaging.					
37244327	9	55	theme	novel	1268:1272	arg1	film					1288:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	3	56	theme	ZIF	607:609	arg1	-8/zeolite					611:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	zeolitic imidazolate framework (ZIF)-8/zeolite	575:620	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	5	57	theme	%	896:896	arg1	activity					871:878	antioxidant activity	859:878	antioxidant activity of around 69.55 %	859:896	The characterization results suggested that pure LCNF showed antioxidant activity of around 69.55 %.					
37244327	1	58	theme	climacteric	246:256	arg1	fruits					258:263	climacteric fruits	246:263	climacteric fruits	246:263	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	1	58	theme	climacteric	246:256	arg1	life					210:213	the shelf life	200:213	the shelf life of fresh produce	200:230	Ethylene, a ripening hormone, is critical in limiting the shelf life of fresh produce, specifically climacteric fruits and vegetables.					
37244327	8	59	theme	high	1224:1227	arg1	quality					1229:1235	their high quality	1218:1235	their high quality	1218:1235	In contrast, a banana package consisting of LCNF/GG/MOF-4 film maintained their high quality in terms of colour.					
37244327	9	60	theme	biodegradable	1274:1286	arg1	film					1288:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film	1257:1291	Fabricated novel biodegradable film has potential application prospects for being used in prolonging the shelf life of fresh produce.					
37244327	3	61	dep	LCNF	491:494	arg1	extracted					497:505	extracted	497:505	extracted from sugarcane bagasse	497:528	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	3	62	theme	guar	535:538	arg1	GG					545:546	GG	545:546	GG	545:546	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
37244327	3	62	theme	guar	535:538	arg1	gum					540:542	guar gum	535:542	guar gum (GG)	535:547	In this investigation, biodegradable film was fabricated using LCNF (extracted from sugarcane bagasse) and guar gum (GG) which was reinforced with zeolitic imidazolate framework (ZIF)-8/zeolite.					
35571611	3	0	theme	iERM	503:506	arg1	pathology					508:516	iERM pathology	503:516	iERM pathology	503:516	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	3	1	theme	proteomics	542:551	arg1	analysis					553:560	a sensitive label-free proteomics analysis	519:560	a sensitive label-free proteomics analysis	519:560	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	11	2	theme	additional	2043:2052	arg1	targets					2054:2060	additional targets	2043:2060	additional targets for treating and preventing iERM	2043:2093	More clinical parameters also need to be identified to complete the analysis, and those could provide additional targets for treating and preventing iERM.					
35571611	6	3	theme	cell	1209:1212	arg1	proliferation					1214:1226	cell proliferation	1209:1226	cell proliferation	1209:1226	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	3	4	theme	sensitive	521:529	arg1	analysis					553:560	a sensitive label-free proteomics analysis	519:560	a sensitive label-free proteomics analysis	519:560	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	2	5	theme	humor	374:378	arg1	composition					347:357	the differential protein composition	322:357	the differential protein composition of the aqueous humor (AH)	322:383	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	1	6	theme	fibrocellular	181:193	arg1	membrane					147:154	Idiopathic epiretinal membrane	125:154	Idiopathic epiretinal membrane (iERM)	125:161	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	6	theme	fibrocellular	181:193	arg1	change					195:200	a pathological fibrocellular change	166:200	a pathological fibrocellular change in the vitreoretinal junction over the macular area	166:252	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	8	7	link	enzyme-linked	1596:1608	arg1	assay					1624:1628	an enzyme-linked immunosorbent assay	1593:1628	an enzyme-linked immunosorbent assay	1593:1628	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	5	8	dep	expressed	953:961	arg1	upregulated					1031:1041	upregulated	1031:1041	were upregulated	1026:1041	Eight proteins were differentially expressed between the iERM and control samples, among which six proteins were upregulated and two were downregulated.					
35571611	5	8	dep	expressed	953:961	arg1	downregulated					1056:1068	downregulated	1056:1068	were downregulated	1051:1068	Eight proteins were differentially expressed between the iERM and control samples, among which six proteins were upregulated and two were downregulated.					
35571611	1	9	from	change	195:200	arg1	junction					223:230	the vitreoretinal junction	205:230	the vitreoretinal junction	205:230	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	7	10	theme	retinal	1411:1417	arg1	thickness					1419:1427	the central retinal thickness	1399:1427	the central retinal thickness	1399:1427	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	1	11	theme	vitreoretinal	209:221	arg1	junction					223:230	the vitreoretinal junction	205:230	the vitreoretinal junction	205:230	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	3	12	theme	AH	587:588	arg1	expressions					598:608	AH protein expressions	587:608	AH protein expressions	587:608	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	4	13	from	patients	857:864	arg1	eyes					844:847	individual human cataract eyes	818:847	individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	818:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	10	14	theme	aqueous	1859:1865	arg1	Lumican					1836:1842	Lumican	1836:1842	Lumican	1836:1842	Lumican is a potential aqueous biomarker for predicting iERM development and monitoring its progression.					
35571611	10	14	theme	aqueous	1859:1865	arg1	biomarker					1867:1875	a potential aqueous biomarker	1847:1875	a potential aqueous biomarker for predicting iERM development and monitoring its progression	1847:1938	Lumican is a potential aqueous biomarker for predicting iERM development and monitoring its progression.					
35571611	1	15	theme	epiretinal	136:145	arg1	iERM					157:160	iERM	157:160	iERM	157:160	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	15	theme	epiretinal	136:145	arg1	change					195:200	a pathological fibrocellular change	166:200	a pathological fibrocellular change in the vitreoretinal junction over the macular area	166:252	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	15	theme	epiretinal	136:145	arg1	membrane					147:154	Idiopathic epiretinal membrane	125:154	Idiopathic epiretinal membrane (iERM)	125:161	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	16	theme	Idiopathic	125:134	arg1	iERM					157:160	iERM	157:160	iERM	157:160	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	16	theme	Idiopathic	125:134	arg1	change					195:200	a pathological fibrocellular change	166:200	a pathological fibrocellular change in the vitreoretinal junction over the macular area	166:252	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	16	theme	Idiopathic	125:134	arg1	membrane					147:154	Idiopathic epiretinal membrane	125:154	Idiopathic epiretinal membrane (iERM)	125:161	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	9	17	theme	cell	1772:1775	arg1	proliferation					1777:1789	cell proliferation	1772:1789	cell proliferation	1772:1789	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	6	18	theme	extracellular	1233:1245	arg1	remodeling					1254:1263	extracellular matrix remodeling	1233:1263	extracellular matrix remodeling	1233:1263	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	4	19	theme	ultra-high-performance	688:709	arg1	spectrometry					745:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	4	20	with	patients	857:864	arg1	iERM					871:874	iERM	871:874	iERM	871:874	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	7	21	theme	multiple	1280:1287	arg1	proteins					1289:1296	multiple proteins	1280:1296	multiple proteins	1280:1296	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	7	21	theme	multiple	1280:1287	arg1	lumican					1309:1315	lumican	1309:1315	lumican	1309:1315	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	7	21	theme	multiple	1280:1287	arg1	kinase					1335:1340	cyclin-dependent kinase 13	1318:1343	cyclin-dependent kinase 13	1318:1343	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	7	21	theme	multiple	1280:1287	arg1	chain					1371:1375	collagen alpha-3(VI) chain	1350:1375	collagen alpha-3(VI) chain	1350:1375	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	7	22	from	response	1458:1465	arg1	process					1485:1491	the pathogenic process	1470:1491	the pathogenic process of iERM	1470:1499	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	4	23	theme	chromatography-tandem	718:738	arg1	spectrometry					745:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	0	24	theme	Idiopathic	75:84	arg1	Membrane					97:104	Idiopathic Epiretinal Membrane	75:104	Idiopathic Epiretinal Membrane	75:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	8	25	theme	lumican	1529:1535	arg1	level					1520:1524	the AH level	1513:1524	the AH level of lumican	1513:1535	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	4	26	from	controls	895:902	arg1	eyes					844:847	individual human cataract eyes	818:847	individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	818:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	0	27	from	Thickness	48:56	arg1	Patients					61:68	Patients	61:68	Patients with Idiopathic Epiretinal Membrane	61:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	4	28	theme	individual	818:827	arg1	eyes					844:847	individual human cataract eyes	818:847	individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	818:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	11	29	theme	clinical	1946:1953	arg1	parameters					1955:1964	More clinical parameters	1941:1964	More clinical parameters	1941:1964	More clinical parameters also need to be identified to complete the analysis, and those could provide additional targets for treating and preventing iERM.					
35571611	8	30	from	Changes	1502:1508	arg1	level					1520:1524	the AH level	1513:1524	the AH level of lumican	1513:1535	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	9	31	theme	matrix	1828:1833	arg1	reactions					1761:1769	immune reactions	1754:1769	immune reactions	1754:1769	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	9	31	theme	matrix	1828:1833	arg1	proliferation					1777:1789	cell proliferation	1772:1789	cell proliferation	1772:1789	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	9	31	theme	matrix	1828:1833	arg1	remodeling					1796:1805	remodeling	1796:1805	remodeling of the extracellular matrix	1796:1833	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	0	32	theme	Aqueous	0:6	arg1	Lumican					8:14	Aqueous Lumican	0:14	Aqueous Lumican	0:14	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	1	33	theme	possible	264:271	arg1	mechanisms					284:293	possible pathogenic mechanisms	264:293	possible pathogenic mechanisms	264:293	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	3	34	theme	new	457:459	arg1	insights					461:468	new insights	457:468	new insights into the molecular mechanisms of iERM pathology	457:516	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	7	35	theme	alpha-3	1359:1365	arg1	chain					1371:1375	collagen alpha-3(VI) chain	1350:1375	collagen alpha-3(VI) chain	1350:1375	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	10	36	theme	iERM	1892:1895	arg1	development					1897:1907	iERM development	1892:1907	iERM development	1892:1907	Lumican is a potential aqueous biomarker for predicting iERM development and monitoring its progression.					
35571611	2	37	theme	potential	399:407	arg1	changes					419:425	potential molecular changes	399:425	potential molecular changes associated with iERM	399:446	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	0	38	theme	Central	32:38	arg1	Thickness					48:56	Central Retinal Thickness	32:56	Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane	32:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	6	39	theme	ontology	1078:1085	arg1	analysis					1092:1099	A gene ontology (GO) analysis	1071:1099	A gene ontology (GO) analysis	1071:1099	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	3	40	with	patients	613:620	arg1	cataracts					627:635	cataracts	627:635	cataracts with or without iERM	627:656	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	3	41	theme	molecular	479:487	arg1	mechanisms					489:498	the molecular mechanisms	475:498	the molecular mechanisms of iERM pathology	475:516	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	7	42	dep	chain	1371:1375	arg1	VI					1367:1368	VI	1367:1368	VI	1367:1368	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	8	43	theme	immunosorbent	1610:1622	arg1	assay					1624:1628	an enzyme-linked immunosorbent assay	1593:1628	an enzyme-linked immunosorbent assay	1593:1628	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	4	44	theme	cataract	835:842	arg1	eyes					844:847	individual human cataract eyes	818:847	individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	818:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	2	45	theme	differential	326:337	arg1	composition					347:357	the differential protein composition	322:357	the differential protein composition of the aqueous humor (AH)	322:383	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	9	46	theme	pathological	1654:1665	arg1	pathways					1667:1674	several pathological pathways	1646:1674	several pathological pathways involved in iERM	1646:1691	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	6	47	theme	several	1148:1154	arg1	remodeling					1254:1263	extracellular matrix remodeling	1233:1263	extracellular matrix remodeling	1233:1263	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	47	theme	several	1148:1154	arg1	proliferation					1214:1226	cell proliferation	1209:1226	cell proliferation	1209:1226	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	47	theme	several	1148:1154	arg1	interactions					1195:1206	immunity interactions	1186:1206	immunity interactions	1186:1206	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	47	theme	several	1148:1154	arg1	processes					1167:1175	several biological processes	1148:1175	several biological processes	1148:1175	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	4	48	with	controls	895:902	arg1	iERM					871:874	iERM	871:874	iERM	871:874	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	3	49	theme	pathology	508:516	arg1	mechanisms					489:498	the molecular mechanisms	475:498	the molecular mechanisms of iERM pathology	475:516	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	3	50	theme	label-free	531:540	arg1	analysis					553:560	a sensitive label-free proteomics analysis	519:560	a sensitive label-free proteomics analysis	519:560	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	7	51	theme	iERM	1496:1499	arg1	process					1485:1491	the pathogenic process	1470:1491	the pathogenic process of iERM	1470:1499	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	7	52	theme	pathogenic	1474:1483	arg1	process					1485:1491	the pathogenic process	1470:1491	the pathogenic process of iERM	1470:1499	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	0	53	with	Patients	61:68	arg1	Membrane					97:104	Idiopathic Epiretinal Membrane	75:104	Idiopathic Epiretinal Membrane	75:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	1	54	theme	pathological	168:179	arg1	membrane					147:154	Idiopathic epiretinal membrane	125:154	Idiopathic epiretinal membrane (iERM)	125:161	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	1	54	theme	pathological	168:179	arg1	change					195:200	a pathological fibrocellular change	166:200	a pathological fibrocellular change in the vitreoretinal junction over the macular area	166:252	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	4	55	theme	age-matched	883:893	arg1	controls					895:902	10 age-matched controls	880:902	10 age-matched controls without iERM	880:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	6	56	theme	immunity	1186:1193	arg1	interactions					1195:1206	immunity interactions	1186:1206	immunity interactions	1186:1206	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	7	57	theme	multifactorial	1443:1456	arg1	response					1458:1465	a multifactorial response	1441:1465	a multifactorial response in the pathogenic process of iERM	1441:1499	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	9	58	theme	proteomic	1724:1732	arg1	analysis					1734:1741	a proteomic analysis	1722:1741	a proteomic analysis	1722:1741	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	3	59	theme	protein	590:596	arg1	expressions					598:608	AH protein expressions	587:608	AH protein expressions	587:608	To gain new insights into the molecular mechanisms of iERM pathology, a sensitive label-free proteomics analysis was performed to compare AH protein expressions in patients with cataracts with or without iERM.					
35571611	9	60	theme	immune	1754:1759	arg1	reactions					1761:1769	immune reactions	1754:1769	immune reactions	1754:1769	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	7	61	theme	central	1403:1409	arg1	thickness					1419:1427	the central retinal thickness	1399:1427	the central retinal thickness	1399:1427	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	4	62	theme	mass	740:743	arg1	spectrometry					745:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	5	63	theme	iERM	975:978	arg1	samples					992:998	the iERM and control samples	971:998	samples	992:998	Eight proteins were differentially expressed between the iERM and control samples, among which six proteins were upregulated and two were downregulated.					
35571611	6	64	theme	gene	1073:1076	arg1	ontology					1078:1085	gene ontology	1073:1085	A gene ontology (GO) analysis	1071:1099	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	8	65	theme	AH	1517:1518	arg1	level					1520:1524	the AH level	1513:1524	the AH level of lumican	1513:1535	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	6	66	theme	matrix	1247:1252	arg1	remodeling					1254:1263	extracellular matrix remodeling	1233:1263	extracellular matrix remodeling	1233:1263	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	10	67	theme	potential	1849:1857	arg1	Lumican					1836:1842	Lumican	1836:1842	Lumican	1836:1842	Lumican is a potential aqueous biomarker for predicting iERM development and monitoring its progression.					
35571611	10	67	theme	potential	1849:1857	arg1	biomarker					1867:1875	a potential aqueous biomarker	1847:1875	a potential aqueous biomarker for predicting iERM development and monitoring its progression	1847:1938	Lumican is a potential aqueous biomarker for predicting iERM development and monitoring its progression.					
35571611	4	68	theme	nanoflow	679:686	arg1	spectrometry					745:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	0	69	theme	Epiretinal	86:95	arg1	Membrane					97:104	Idiopathic Epiretinal Membrane	75:104	Idiopathic Epiretinal Membrane	75:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	4	70	theme	liquid	711:716	arg1	spectrometry					745:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry	679:756	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	2	71	from	Changes	311:317	arg1	composition					347:357	the differential protein composition	322:357	the differential protein composition of the aqueous humor (AH)	322:383	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	6	72	dep	ontology	1078:1085	arg1	GO					1088:1089	GO	1088:1089	GO	1088:1089	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	4	73	theme	AH	801:802	arg1	compositions					781:792	protein compositions	773:792	protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	773:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	7	74	theme	cyclin-dependent	1318:1333	arg1	kinase					1335:1340	cyclin-dependent kinase 13	1318:1343	cyclin-dependent kinase 13	1318:1343	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	0	75	theme	Proteome	109:116	arg1	Study					118:122	A Proteome Study	107:122	A Proteome Study	107:122	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	9	76	theme	extracellular	1814:1826	arg1	matrix					1828:1833	the extracellular matrix	1810:1833	the extracellular matrix	1810:1833	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	5	77	theme	control	984:990	arg1	samples					992:998	the iERM and control samples	971:998	samples	992:998	Eight proteins were differentially expressed between the iERM and control samples, among which six proteins were upregulated and two were downregulated.					
35571611	4	78	theme	protein	773:779	arg1	compositions					781:792	protein compositions	773:792	protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	773:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	1	79	theme	pathogenic	273:282	arg1	mechanisms					284:293	possible pathogenic mechanisms	264:293	possible pathogenic mechanisms	264:293	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	7	80	theme	collagen	1350:1357	arg1	chain					1371:1375	collagen alpha-3(VI) chain	1350:1375	collagen alpha-3(VI) chain	1350:1375	Additionally, multiple proteins, including lumican, cyclin-dependent kinase 13, and collagen alpha-3(VI) chain, were correlated with the central retinal thickness, indicating a multifactorial response in the pathogenic process of iERM.					
35571611	2	81	theme	molecular	409:417	arg1	changes					419:425	potential molecular changes	399:425	potential molecular changes associated with iERM	399:446	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	0	82	theme	Retinal	40:46	arg1	Thickness					48:56	Central Retinal Thickness	32:56	Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane	32:104	Aqueous Lumican Correlates with Central Retinal Thickness in Patients with Idiopathic Epiretinal Membrane: A Proteome Study.					
35571611	8	83	theme	enzyme-linked	1596:1608	arg1	assay					1624:1628	an enzyme-linked immunosorbent assay	1593:1628	an enzyme-linked immunosorbent assay	1593:1628	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
35571611	2	84	theme	protein	339:345	arg1	composition					347:357	the differential protein composition	322:357	the differential protein composition of the aqueous humor (AH)	322:383	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	9	85	theme	several	1646:1652	arg1	pathways					1667:1674	several pathological pathways	1646:1674	several pathological pathways involved in iERM	1646:1691	In conclusion, several pathological pathways involved in iERM were identified in the AH by a proteomic analysis, including immune reactions, cell proliferation, and remodeling of the extracellular matrix.					
35571611	6	86	theme	biological	1156:1165	arg1	remodeling					1254:1263	extracellular matrix remodeling	1233:1263	extracellular matrix remodeling	1233:1263	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	86	theme	biological	1156:1165	arg1	proliferation					1214:1226	cell proliferation	1209:1226	cell proliferation	1209:1226	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	86	theme	biological	1156:1165	arg1	interactions					1195:1206	immunity interactions	1186:1206	immunity interactions	1186:1206	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	6	86	theme	biological	1156:1165	arg1	processes					1167:1175	several biological processes	1148:1175	several biological processes	1148:1175	A gene ontology (GO) analysis revealed that iERM was closely associated with several biological processes, such as immunity interactions, cell proliferation, and extracellular matrix remodeling.					
35571611	4	87	theme	human	829:833	arg1	eyes					844:847	individual human cataract eyes	818:847	individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM	818:915	This study employed nanoflow ultra-high-performance liquid chromatography-tandem mass spectrometry to investigate protein compositions of the AH obtained from individual human cataract eyes from 10 patients with iERM and 10 age-matched controls without iERM.					
35571611	1	88	theme	macular	241:247	arg1	area					249:252	the macular area	237:252	the macular area	237:252	Idiopathic epiretinal membrane (iERM) is a pathological fibrocellular change in the vitreoretinal junction over the macular area; however, possible pathogenic mechanisms remain unclear.					
35571611	2	89	theme	aqueous	366:372	arg1	AH					381:382	AH	381:382	AH	381:382	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	2	89	theme	aqueous	366:372	arg1	humor					374:378	aqueous humor	366:378	the aqueous humor (AH)	362:383	Changes in the differential protein composition of the aqueous humor (AH) may represent potential molecular changes associated with iERM.					
35571611	8	90	dep	iERM	1545:1548	arg1	samples					1562:1568	samples	1562:1568	samples	1562:1568	Changes in the AH level of lumican between iERM and control samples were also confirmed by an enzyme-linked immunosorbent assay.					
36073926	16	0	theme	sustainable	2491:2501	arg1	practices					2516:2524	sustainable agricultural practices	2491:2524	sustainable agricultural practices that are less dependent on agrochemicals	2491:2565	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	14	1	theme	communities	2126:2136	arg1	composition					2092:2102	the composition	2088:2102	the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy	2088:2200	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	10	2	theme	developmental	1550:1562	arg1	stages					1564:1569	earlier developmental stages	1542:1569	earlier developmental stages	1542:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	8	3	theme	soil	1148:1151	arg1	communities					1163:1173	the root endosphere and bulk soil bacterial communities	1119:1173	the root endosphere and bulk soil bacterial communities	1119:1173	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	2	4	from	sugars	309:314	arg1	exudates					368:375	maize root exudates	357:375	maize root exudates	357:375	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	10	5	theme	developmental	1594:1606	arg1	stages					1608:1613	later developmental stages	1588:1613	later developmental stages	1588:1613	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	3	6	theme	maize	525:529	arg1	genotypes					531:539	240 maize genotypes	521:539	240 maize genotypes grown in a semihydroponic system	521:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	4	7	theme	maize	689:693	arg1	stages					709:714	three maize developmental stages	683:714	three maize developmental stages	683:714	These twelve maize genotypes were grown in a replicated field experiment in which samples were collected at three maize developmental stages.					
36073926	6	8	from	soils	822:826	arg1	Sugars					776:781	Sugars	776:781	Sugars	776:781	Sugars and JA concentrations from rhizosphere soils were also quantified.					
36073926	6	8	from	soils	822:826	arg1	concentrations					790:803	JA concentrations	787:803	JA concentrations	787:803	Sugars and JA concentrations from rhizosphere soils were also quantified.					
36073926	14	9	theme	maize	2141:2145	arg1	composition					2092:2102	the composition	2088:2102	the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy	2088:2200	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	10	10	theme	sugars	1428:1433	arg1	effects					1408:1414	The effects	1404:1414	The effects of specific sugars on the composition of the rhizobacterial communities	1404:1486	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	15	11	from	stages	2336:2341	arg1	assemblage					2262:2271	the assemblage	2258:2271	the assemblage of rhizobacterial communities at different maize developmental stages	2258:2341	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	8	12	theme	growth	1206:1211	arg1	stages					1213:1218	specific growth stages	1197:1218	specific growth stages	1197:1218	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	4	13	theme	replicated	620:629	arg1	experiment					637:646	a replicated field experiment	618:646	a replicated field experiment in which samples were collected at three maize developmental stages	618:714	These twelve maize genotypes were grown in a replicated field experiment in which samples were collected at three maize developmental stages.					
36073926	7	14	dep	stages	1080:1085	arg1	development					1093:1103	plant development	1087:1103	multiple stages plant development	1071:1103	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	7	15	theme	community	1046:1054	arg1	composition					1056:1066	the rhizosphere bacterial community composition	1020:1066	the rhizosphere bacterial community composition	1020:1066	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	9	16	theme	JA	1232:1233	arg1	concentration					1235:1247	JA concentration	1232:1247	JA concentration	1232:1247	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	1	17	theme	exudate	209:215	arg1	compounds					217:225	the many exudate compounds	200:225	the many exudate compounds	200:225	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	15	18	theme	developmental	2322:2334	arg1	stages					2336:2341	different maize developmental stages	2306:2341	different maize developmental stages	2306:2341	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	7	19	from	variability	897:907	arg1	sugars					912:917	sugars	912:917	sugars	912:917	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	7	19	from	variability	897:907	arg1	concentration					926:938	JA concentration	923:938	JA concentration	923:938	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	7	19	from	variability	897:907	arg1	exudates					948:955	root exudates	943:955	root exudates	943:955	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	7	20	theme	rhizosphere	1024:1034	arg1	composition					1056:1066	the rhizosphere bacterial community composition	1020:1066	the rhizosphere bacterial community composition	1020:1066	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	12	21	theme	IMPORTANCE	1765:1774	arg1	Roots					1776:1780	IMPORTANCE Roots	1765:1780	IMPORTANCE Roots	1765:1780	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	9	22	theme	soil	1278:1281	arg1	samples					1283:1289	rhizosphere soil samples	1266:1289	rhizosphere soil samples	1266:1289	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	10	23	theme	rhizobacterial	1461:1474	arg1	communities					1476:1486	the rhizobacterial communities	1457:1486	the rhizobacterial communities	1457:1486	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	13	24	theme	root	1932:1935	arg1	exudates					1937:1944	root exudates	1932:1944	root exudates that participate in these interactions	1932:1983	However, the exact chemical compounds in root exudates that participate in these interactions are not fully known.					
36073926	0	25	theme	Rhizosphere	69:79	arg1	Communities					91:101	Maize Rhizosphere Bacterial Communities	63:101	Maize Rhizosphere Bacterial Communities	63:101	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	0	26	from	Sugars	0:5	arg1	Exudates					47:54	Root Exudates	42:54	Root Exudates	42:54	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	14	27	theme	important	2160:2168	arg1	maize					2141:2145	maize	2141:2145	maize	2141:2145	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	14	27	theme	important	2160:2168	arg1	crop					2170:2173	an important crop	2157:2173	an important crop for food, feed, and energy	2157:2200	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	1	28	dep	shaping	132:138	arg1	microbiomes					160:170	the root-associated microbiomes	140:170	shaping the root-associated microbiomes	132:170	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	7	29	theme	JA	923:924	arg1	concentration					926:938	JA concentration	923:938	JA concentration	923:938	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	14	30	theme	jasmonic	2064:2071	arg1	acid					2073:2076	the phytohormone jasmonic acid	2047:2076	the phytohormone jasmonic acid	2047:2076	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	11	31	theme	exudate	1675:1681	arg1	JA					1642:1643	JA	1642:1643	JA	1642:1643	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	31	theme	exudate	1675:1681	arg1	compounds					1683:1691	important root exudate compounds	1660:1691	important root exudate compounds that influence the composition of the maize rhizobacterial communities	1660:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	31	theme	exudate	1675:1681	arg1	sugars					1649:1654	sugars	1649:1654	sugars	1649:1654	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	2	32	theme	rhizobacterial	384:397	arg1	communities					399:409	the rhizobacterial communities	380:409	the rhizobacterial communities	380:409	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	13	33	theme	exact	1904:1908	arg1	compounds					1919:1927	the exact chemical compounds	1900:1927	the exact chemical compounds in root exudates that participate in these interactions	1900:1983	However, the exact chemical compounds in root exudates that participate in these interactions are not fully known.					
36073926	3	34	theme	maize	419:423	arg1	genotypes					425:433	Twelve maize genotypes	412:433	Twelve maize genotypes	412:433	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	5	35	theme	rRNA	725:728	arg1	gene					730:733	The 16S rRNA gene	717:733	The 16S rRNA gene (V4 region)	717:745	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	5	35	theme	rRNA	725:728	arg1	region					739:744	V4 region	736:744	V4 region	736:744	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	0	36	from	Concentration	25:37	arg1	Exudates					47:54	Root Exudates	42:54	Root Exudates	42:54	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	2	37	theme	maize	357:361	arg1	exudates					368:375	maize root exudates	357:375	maize root exudates	357:375	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	15	38	theme	maize	2316:2320	arg1	stages					2336:2341	different maize developmental stages	2306:2341	different maize developmental stages	2306:2341	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	16	39	from	compounds	2373:2381	arg1	exudates					2391:2398	root exudates	2386:2398	root exudates that contribute to shape the rhizobiome	2386:2438	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	0	40	theme	Jasmonic	11:18	arg1	Acid					20:23	Jasmonic Acid	11:23	Jasmonic Acid Concentration	11:37	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	10	41	from	stages	1564:1569	arg1	trehalose					1575:1583	trehalose	1575:1583	trehalose at later developmental stages	1575:1613	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	10	41	from	stages	1564:1569	arg1	effects					1520:1526	larger effects	1513:1526	larger effects of sucrose at earlier developmental stages	1513:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	14	42	theme	rhizobacterial	2111:2124	arg1	communities					2126:2136	the rhizobacterial communities	2107:2136	the rhizobacterial communities	2107:2136	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	11	43	theme	maize	1731:1735	arg1	communities					1752:1762	the maize rhizobacterial communities	1727:1762	the maize rhizobacterial communities	1727:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	15	44	theme	rhizobacterial	2276:2289	arg1	communities					2291:2301	rhizobacterial communities	2276:2301	rhizobacterial communities	2276:2301	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	12	45	theme	plant	1866:1870	arg1	growth					1872:1877	plant growth	1866:1877	plant growth	1866:1877	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	10	46	theme	earlier	1542:1548	arg1	stages					1564:1569	earlier developmental stages	1542:1569	earlier developmental stages	1542:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	3	47	theme	sugars	483:488	arg1	concentrations					465:478	variable concentrations	456:478	variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system	456:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	0	48	theme	Root	42:45	arg1	Exudates					47:54	Root Exudates	42:54	Root Exudates	42:54	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	6	49	theme	rhizosphere	810:820	arg1	soils					822:826	rhizosphere soils	810:826	rhizosphere soils	810:826	Sugars and JA concentrations from rhizosphere soils were also quantified.					
36073926	2	50	from	exudates	368:375	arg1	influence					296:304	the influence	292:304	the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities	292:409	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	10	51	theme	sucrose	1531:1537	arg1	trehalose					1575:1583	trehalose	1575:1583	trehalose at later developmental stages	1575:1613	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	10	51	theme	sucrose	1531:1537	arg1	effects					1520:1526	larger effects	1513:1526	larger effects of sucrose at earlier developmental stages	1513:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	7	52	theme	genotypic	887:895	arg1	variability					897:907	the maize genotypic variability	877:907	the maize genotypic variability	877:907	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	10	53	from	stages	1608:1613	arg1	trehalose					1575:1583	trehalose	1575:1583	trehalose at later developmental stages	1575:1613	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	10	53	from	stages	1608:1613	arg1	effects					1520:1526	larger effects	1513:1526	larger effects of sucrose at earlier developmental stages	1513:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	13	54	from	compounds	1919:1927	arg1	exudates					1937:1944	root exudates	1932:1944	root exudates that participate in these interactions	1932:1983	However, the exact chemical compounds in root exudates that participate in these interactions are not fully known.					
36073926	12	55	theme	soil	1839:1842	arg1	microbes					1844:1851	soil microbes	1839:1851	soil microbes that promote plant growth and health	1839:1888	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	10	56	from	effects	1408:1414	arg1	composition					1442:1452	the composition	1438:1452	the composition of the rhizobacterial communities	1438:1486	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	11	57	theme	communities	1752:1762	arg1	composition					1712:1722	the composition	1708:1722	the composition of the maize rhizobacterial communities	1708:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	16	58	theme	future	2462:2467	arg1	strategies					2469:2478	future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals	2462:2565	future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals	2462:2565	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	2	59	theme	concentrations	339:352	arg1	influence					296:304	the influence	292:304	the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities	292:409	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	16	60	theme	agricultural	2503:2514	arg1	practices					2516:2524	sustainable agricultural practices	2491:2524	sustainable agricultural practices that are less dependent on agrochemicals	2491:2565	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	15	61	theme	communities	2291:2301	arg1	assemblage					2262:2271	the assemblage	2258:2271	the assemblage of rhizobacterial communities at different maize developmental stages	2258:2341	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	5	62	theme	V4	736:737	arg1	gene					730:733	The 16S rRNA gene	717:733	The 16S rRNA gene (V4 region)	717:745	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	5	62	theme	V4	736:737	arg1	region					739:744	V4 region	736:744	V4 region	736:744	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	3	63	theme	JA	494:495	arg1	concentrations					465:478	variable concentrations	456:478	variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system	456:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	8	64	theme	endosphere	1128:1137	arg1	communities					1163:1173	the root endosphere and bulk soil bacterial communities	1119:1173	the root endosphere and bulk soil bacterial communities	1119:1173	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	11	65	theme	important	1660:1668	arg1	JA					1642:1643	JA	1642:1643	JA	1642:1643	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	65	theme	important	1660:1668	arg1	compounds					1683:1691	important root exudate compounds	1660:1691	important root exudate compounds that influence the composition of the maize rhizobacterial communities	1660:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	65	theme	important	1660:1668	arg1	sugars					1649:1654	sugars	1649:1654	sugars	1649:1654	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	16	66	theme	root	2386:2389	arg1	exudates					2391:2398	root exudates	2386:2398	root exudates that contribute to shape the rhizobiome	2386:2438	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	3	67	theme	240	521:523	arg1	genotypes					531:539	240 maize genotypes	521:539	240 maize genotypes grown in a semihydroponic system	521:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	8	68	theme	bulk	1143:1146	arg1	soil					1148:1151	bulk soil	1143:1151	bulk soil	1143:1151	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	10	69	theme	later	1588:1592	arg1	stages					1608:1613	later developmental stages	1588:1613	later developmental stages	1588:1613	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	2	70	theme	acid	329:332	arg1	concentrations					339:352	jasmonic acid (JA) concentrations	320:352	jasmonic acid (JA) concentrations	320:352	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	7	71	theme	plant	1087:1091	arg1	development					1093:1103	plant development	1087:1103	multiple stages plant development	1071:1103	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	8	72	theme	bacterial	1153:1161	arg1	communities					1163:1173	the root endosphere and bulk soil bacterial communities	1119:1173	the root endosphere and bulk soil bacterial communities	1119:1173	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	4	73	theme	field	631:635	arg1	experiment					637:646	a replicated field experiment	618:646	a replicated field experiment in which samples were collected at three maize developmental stages	618:714	These twelve maize genotypes were grown in a replicated field experiment in which samples were collected at three maize developmental stages.					
36073926	7	74	theme	multiple	1071:1078	arg1	stages					1080:1085	multiple stages plant development	1071:1103	multiple stages plant development	1071:1103	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	2	75	from	concentrations	339:352	arg1	exudates					368:375	maize root exudates	357:375	maize root exudates	357:375	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	10	76	theme	specific	1419:1426	arg1	sugars					1428:1433	specific sugars	1419:1433	specific sugars	1419:1433	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	3	77	theme	genotypes	531:539	arg1	screening					508:516	a screening	506:516	a screening of 240 maize genotypes grown in a semihydroponic system	506:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	7	78	theme	bacterial	1036:1044	arg1	composition					1056:1066	the rhizosphere bacterial community composition	1020:1066	the rhizosphere bacterial community composition	1020:1066	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	1	79	theme	many	204:207	arg1	compounds					217:225	the many exudate compounds	200:225	the many exudate compounds	200:225	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	8	80	theme	specific	1197:1204	arg1	stages					1213:1218	specific growth stages	1197:1218	specific growth stages	1197:1218	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	1	81	from	important	231:239	arg1	process					249:255	this process	244:255	this process	244:255	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	3	82	theme	semihydroponic	552:565	arg1	system					567:572	a semihydroponic system	550:572	a semihydroponic system	550:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	12	83	with	interactions	1821:1832	arg1	microbes					1844:1851	soil microbes	1839:1851	soil microbes that promote plant growth and health	1839:1888	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	7	84	theme	semihydroponic	974:987	arg1	system					989:994	the semihydroponic system	970:994	the semihydroponic system	970:994	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	4	85	theme	developmental	695:707	arg1	stages					709:714	three maize developmental stages	683:714	three maize developmental stages	683:714	These twelve maize genotypes were grown in a replicated field experiment in which samples were collected at three maize developmental stages.					
36073926	0	86	theme	Maize	63:67	arg1	Communities					91:101	Maize Rhizosphere Bacterial Communities	63:101	Maize Rhizosphere Bacterial Communities	63:101	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	9	87	theme	rhizosphere	1266:1276	arg1	samples					1283:1289	rhizosphere soil samples	1266:1289	rhizosphere soil samples	1266:1289	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	1	88	theme	root-associated	144:158	arg1	microbiomes					160:170	the root-associated microbiomes	140:170	shaping the root-associated microbiomes	132:170	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	16	89	theme	specific	2364:2371	arg1	compounds					2373:2381	the specific compounds	2360:2381	the specific compounds in root exudates that contribute to shape the rhizobiome	2360:2438	Knowledge about the specific compounds in root exudates that contribute to shape the rhizobiome will be important for future strategies to develop sustainable agricultural practices that are less dependent on agrochemicals.					
36073926	0	90	theme	Bacterial	81:89	arg1	Communities					91:101	Maize Rhizosphere Bacterial Communities	63:101	Maize Rhizosphere Bacterial Communities	63:101	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	7	91	theme	root	943:946	arg1	exudates					948:955	root exudates	943:955	root exudates	943:955	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	2	92	from	influence	296:304	arg1	exudates					368:375	maize root exudates	357:375	maize root exudates	357:375	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	2	92	from	influence	296:304	arg1	communities					399:409	the rhizobacterial communities	380:409	the rhizobacterial communities	380:409	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	5	93	theme	16S	721:723	arg1	gene					730:733	The 16S rRNA gene	717:733	The 16S rRNA gene (V4 region)	717:745	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	5	93	theme	16S	721:723	arg1	region					739:744	V4 region	736:744	V4 region	736:744	The 16S rRNA gene (V4 region) was amplified and sequenced.					
36073926	14	94	theme	phytohormone	2051:2062	arg1	acid					2073:2076	the phytohormone jasmonic acid	2047:2076	the phytohormone jasmonic acid	2047:2076	Here, we investigated whether sugars and the phytohormone jasmonic acid influence the composition of the rhizobacterial communities of maize, which is an important crop for food, feed, and energy.					
36073926	12	95	from	interactions	1821:1832	arg1	important					1808:1816	important	1808:1816	important	1808:1816	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	13	96	theme	chemical	1910:1917	arg1	compounds					1919:1927	the exact chemical compounds	1900:1927	the exact chemical compounds in root exudates that participate in these interactions	1900:1983	However, the exact chemical compounds in root exudates that participate in these interactions are not fully known.					
36073926	2	97	theme	root	363:366	arg1	exudates					368:375	maize root exudates	357:375	maize root exudates	357:375	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	12	98	from	important	1808:1816	arg1	interactions					1821:1832	interactions	1821:1832	interactions with soil microbes that promote plant growth and health	1821:1888	IMPORTANCE Roots secrete exudates that are important in interactions with soil microbes that promote plant growth and health.					
36073926	10	99	theme	communities	1476:1486	arg1	composition					1442:1452	the composition	1438:1452	the composition of the rhizobacterial communities	1438:1486	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	0	100	theme	Acid	20:23	arg1	Concentration					25:37	Jasmonic Acid Concentration	11:37	Jasmonic Acid Concentration	11:37	Sugars and Jasmonic Acid Concentration in Root Exudates Affect Maize Rhizosphere Bacterial Communities.					
36073926	9	101	theme	rhizobacterial	1339:1352	arg1	communities					1354:1364	the rhizobacterial communities	1335:1364	the rhizobacterial communities	1335:1364	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	1	102	theme	Root	104:107	arg1	exudates					109:116	Root exudates	104:116	Root exudates	104:116	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	10	103	theme	larger	1513:1518	arg1	effects					1520:1526	larger effects	1513:1526	larger effects of sucrose at earlier developmental stages	1513:1569	The effects of specific sugars on the composition of the rhizobacterial communities were also measured, with larger effects of sucrose at earlier developmental stages and trehalose at later developmental stages.					
36073926	3	104	theme	variable	456:463	arg1	concentrations					465:478	variable concentrations	456:478	variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system	456:572	Twelve maize genotypes were identified with variable concentrations of sugars and JA based on a screening of 240 maize genotypes grown in a semihydroponic system.					
36073926	15	105	theme	different	2306:2314	arg1	stages					2336:2341	different maize developmental stages	2306:2341	different maize developmental stages	2306:2341	Our results revealed that both compounds contribute to the assemblage of rhizobacterial communities at different maize developmental stages.					
36073926	9	106	theme	developmental	1373:1385	arg1	stages					1387:1392	all developmental stages	1369:1392	all developmental stages analyzed	1369:1401	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	1	107	from	process	249:255	arg1	important					231:239	important	231:239	important	231:239	Root exudates contribute to shaping the root-associated microbiomes, but it is unclear which of the many exudate compounds are important in this process.					
36073926	2	108	theme	jasmonic	320:327	arg1	JA					335:336	JA	335:336	JA	335:336	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	2	108	theme	jasmonic	320:327	arg1	acid					329:332	jasmonic acid	320:332	jasmonic acid (JA) concentrations	320:352	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	7	109	theme	maize	881:885	arg1	variability					897:907	the maize genotypic variability	877:907	the maize genotypic variability	877:907	The results indicated that the maize genotypic variability in sugars and JA concentration in root exudates, measured in the semihydroponic system, significantly affected the rhizosphere bacterial community composition at multiple stages plant development.					
36073926	4	110	theme	maize	588:592	arg1	genotypes					594:602	These twelve maize genotypes	575:602	These twelve maize genotypes	575:602	These twelve maize genotypes were grown in a replicated field experiment in which samples were collected at three maize developmental stages.					
36073926	11	111	theme	rhizobacterial	1737:1750	arg1	communities					1752:1762	the maize rhizobacterial communities	1727:1762	the maize rhizobacterial communities	1727:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	2	112	theme	sugars	309:314	arg1	influence					296:304	the influence	292:304	the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities	292:409	Here, we focused on understanding the influence of sugars and jasmonic acid (JA) concentrations in maize root exudates on the rhizobacterial communities.					
36073926	8	113	theme	root	1123:1126	arg1	endosphere					1128:1137	root endosphere	1123:1137	root endosphere	1123:1137	In contrast, the root endosphere and bulk soil bacterial communities were only affected at specific growth stages.					
36073926	6	114	theme	JA	787:788	arg1	concentrations					790:803	JA concentrations	787:803	JA concentrations	787:803	Sugars and JA concentrations from rhizosphere soils were also quantified.					
36073926	9	115	dep	Sugars	1221:1226	arg1	quantified					1252:1261	quantified	1252:1261	quantified in rhizosphere soil samples	1252:1289	Sugars and JA concentration as quantified in rhizosphere soil samples confirmed that these two compounds affected the rhizobacterial communities at all developmental stages analyzed.					
36073926	11	116	theme	root	1670:1673	arg1	JA					1642:1643	JA	1642:1643	JA	1642:1643	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	116	theme	root	1670:1673	arg1	compounds					1683:1691	important root exudate compounds	1660:1691	important root exudate compounds that influence the composition of the maize rhizobacterial communities	1660:1762	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
36073926	11	116	theme	root	1670:1673	arg1	sugars					1649:1654	sugars	1649:1654	sugars	1649:1654	Our results indicate that JA and sugars are important root exudate compounds that influence the composition of the maize rhizobacterial communities.					
35738334	12	0	theme	medical	2336:2342	arg1	application					2344:2354	An attractive medical application	2322:2354	An attractive medical application for such a device	2322:2372	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	0	theme	medical	2336:2342	arg1	treatment					2404:2412	post-operative local treatment	2383:2412	post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues	2383:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	8	1	theme	CaCl2	1540:1544	arg1	agent					1582:1586	the constitutional de-crosslinking agent	1547:1586	the constitutional de-crosslinking agent	1547:1586	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	1	theme	CaCl2	1540:1544	arg1	CaCl2					1540:1544	CaCl2	1540:1544	CaCl2 (the constitutional de-crosslinking agent)	1540:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	1	theme	CaCl2	1540:1544	arg1	amounts					1529:1535	the co-loaded amounts	1515:1535	the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent)	1515:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	2	2	theme	rates	543:547	arg1	synchronization					512:526	synchronization	512:526	synchronization of the release rates of the two drugs over 2 h	512:573	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	7	3	theme	designed	1226:1233	arg1	experiment					1256:1265	a statistically designed Fractional Factorial experiment	1210:1265	a statistically designed Fractional Factorial experiment	1210:1265	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	8	4	dep	crosslinker	1418:1428	arg1	acid					1438:1441	citric acid	1431:1441	citric acid	1431:1441	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	4	dep	crosslinker	1418:1428	arg1	acid					1453:1456	oxalic acid	1446:1456	oxalic acid	1446:1456	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	3	5	dep	prolong	791:797	arg1	b					788:788	b	788:788	b	788:788	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	9	6	theme	difference	1594:1603	arg1	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	6	theme	difference	1594:1603	arg1	f2					1644:1645	f2	1644:1645	f2	1644:1645	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	6	theme	difference	1594:1603	arg1	responses					1725:1733	the experimental responses	1708:1733	the experimental responses	1708:1733	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	6	theme	difference	1594:1603	arg1	factor					1636:1641	the similarity factor	1621:1641	the similarity factor	1621:1641	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	6	theme	difference	1594:1603	arg1	f1					1613:1614	f1	1613:1614	f1	1613:1614	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	8	7	theme	de-crosslinking	1566:1580	arg1	agent					1582:1586	the constitutional de-crosslinking agent	1547:1586	the constitutional de-crosslinking agent	1547:1586	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	7	theme	de-crosslinking	1566:1580	arg1	CaCl2					1540:1544	CaCl2	1540:1544	CaCl2 (the constitutional de-crosslinking agent)	1540:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	10	8	theme	exact	2053:2057	arg1	mechanisms					2059:2068	the exact mechanisms	2049:2068	the exact mechanisms of the release processes involved	2049:2102	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	8	9	theme	oxalic	1446:1451	arg1	acid					1453:1456	oxalic acid	1446:1456	oxalic acid	1446:1456	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	1	10	theme	study	161:165	arg1	study					123:127	This study	118:127	This study	118:127	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	10	theme	study	161:165	arg1	continuation					134:145	a continuation	132:145	a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct)	132:354	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	2	11	theme	drugs	560:564	arg1	rates					543:547	the release rates	531:547	the release rates of the two drugs over 2 h	531:573	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	7	12	theme	study	1195:1199	arg1	section					1180:1186	The formulation screening section	1154:1186	The formulation screening section of the study	1154:1199	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	10	13	theme	prediction	1753:1762	arg1	models					1764:1769	The computerized prediction models	1736:1769	The computerized prediction models	1736:1769	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	11	14	theme	multi-drug	2302:2311	arg1	platform					2278:2285	the novel polymeric platform	2258:2285	the novel polymeric platform	2258:2285	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	14	theme	multi-drug	2302:2311	arg1	implant					2313:2319	a multi-drug implant	2300:2319	a multi-drug implant	2300:2319	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	9	15	theme	TT	1655:1656	arg1	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	15	theme	TT	1655:1656	arg1	f2					1644:1645	f2	1644:1645	f2	1644:1645	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	15	theme	TT	1655:1656	arg1	factor					1636:1641	the similarity factor	1621:1641	the similarity factor	1621:1641	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	15	theme	TT	1655:1656	arg1	f1					1613:1614	f1	1613:1614	f1	1613:1614	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	12	16	theme	attractive	2325:2334	arg1	application					2344:2354	An attractive medical application	2322:2354	An attractive medical application for such a device	2322:2372	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	16	theme	attractive	2325:2334	arg1	treatment					2404:2412	post-operative local treatment	2383:2412	post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues	2383:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	8	17	from	amount	1369:1374	arg1	formulation					1383:1393	the formulation	1379:1393	the formulation	1379:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	12	18	from	treatment	2404:2412	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	1	19	theme	model	180:184	arg1	drugs					186:190	two model drugs	176:190	two model drugs	176:190	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	19	theme	model	180:184	arg1	salicylate					200:209	sodium salicylate	193:209	sodium salicylate (highly water-soluble)	193:232	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	19	theme	model	180:184	arg1	indomethacin					238:249	indomethacin	238:249	indomethacin (low water-soluble)	238:269	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	2	20	theme	concentrations	485:498	arg1	de-crosslinker					456:469	de-crosslinker	456:469	de-crosslinker	456:469	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	2	20	theme	concentrations	485:498	arg1	solutions					445:453	calcium chloride solutions	428:453	calcium chloride solutions (de-crosslinker) of different concentrations	428:498	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	7	21	theme	screening	1170:1178	arg1	section					1180:1186	The formulation screening section	1154:1186	The formulation screening section of the study	1154:1199	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	12	22	theme	carcinomatosis	2595:2608	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	1	23	dep	salicylate	200:209	arg1	water-soluble					219:231	water-soluble	219:231	water-soluble	219:231	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	6	24	theme	core-containing	1077:1091	arg1	hydrogel					1093:1100	A PLGA core-containing hydrogel	1070:1100	A PLGA core-containing hydrogel	1070:1100	A PLGA core-containing hydrogel was then produced by ionically crosslinking the Ct.					
35738334	11	25	theme	polymeric	2268:2276	arg1	platform					2278:2285	the novel polymeric platform	2258:2285	the novel polymeric platform	2258:2285	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	25	theme	polymeric	2268:2276	arg1	implant					2313:2319	a multi-drug implant	2300:2319	a multi-drug implant	2300:2319	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	26	theme	similar	2174:2180	arg1	rates					2196:2200	similar (concomitant) rates	2174:2200	similar (concomitant) rates	2174:2200	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	8	27	from	type	1337:1340	arg1	formulation					1383:1393	the formulation	1379:1393	the formulation	1379:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	10	28	theme	factorial	1971:1979	arg1	design					1981:1986	a fractional factorial design	1958:1986	a fractional factorial design	1958:1986	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	1	29	dep	indomethacin	238:249	arg1	water-soluble					256:268	water-soluble	256:268	water-soluble	256:268	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	9	30	used	used	1700:1703	arg2	responses					1725:1733	the experimental responses	1708:1733	the experimental responses	1708:1733	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	30	used	used	1700:1703	arg2	f2					1644:1645	f2	1644:1645	f2	1644:1645	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	30	used	used	1700:1703	arg2	f1					1613:1614	f1	1613:1614	f1	1613:1614	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	30	used	used	1700:1703	arg2	factor					1636:1641	the similarity factor	1621:1641	the similarity factor	1621:1641	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	30	used	used	1700:1703	arg2	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	8	31	dep	type	1337:1340	arg1	amounts					1529:1535	the co-loaded amounts	1515:1535	the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent)	1515:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	31	dep	type	1337:1340	arg1	CaCl2					1540:1544	CaCl2	1540:1544	CaCl2 (the constitutional de-crosslinking agent)	1540:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	31	dep	type	1337:1340	arg1	a					1330:1330	a	1330:1330	a	1330:1330	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	31	dep	type	1337:1340	arg1	agent					1582:1586	the constitutional de-crosslinking agent	1547:1586	the constitutional de-crosslinking agent	1547:1586	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	12	32	theme	combination	2448:2458	arg1	chemotherapy					2460:2471	localized combination chemotherapy	2438:2471	localized combination chemotherapy	2438:2471	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	33	theme	breast	2542:2547	arg1	cancer					2549:2554	breast cancer	2542:2554	breast cancer	2542:2554	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	3	34	theme	cytotoxic	689:697	arg1	drugs					699:703	the two cytotoxic drugs	681:703	the two cytotoxic drugs	681:703	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	1	35	theme	erodible	291:298	arg1	hydrogel					300:307	an erodible hydrogel	288:307	an erodible hydrogel	288:307	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	8	36	theme	crosslinker	1495:1505	arg1	concentration					1468:1480	the concentration	1464:1480	(d) the concentration of the ionic crosslinker	1460:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	36	theme	crosslinker	1495:1505	arg1	crosslinker					1418:1428	ionic crosslinker	1412:1428	ionic crosslinker (citric acid or oxalic acid)	1412:1457	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	2	37	theme	calcium	428:434	arg1	de-crosslinker					456:469	de-crosslinker	456:469	de-crosslinker	456:469	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	2	37	theme	calcium	428:434	arg1	solutions					445:453	calcium chloride solutions	428:453	calcium chloride solutions (de-crosslinker) of different concentrations	428:498	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	8	38	theme	Ct	1345:1346	arg1	e					1512:1512	e	1512:1512	e	1512:1512	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	38	theme	Ct	1345:1346	arg1	type					1404:1407	the type	1400:1407	the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker	1400:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	38	theme	Ct	1345:1346	arg1	type					1337:1340	the type	1333:1340	(a) the type of Ct and (b) its relative amount in the formulation	1329:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	6	39	theme	PLGA	1072:1075	arg1	hydrogel					1093:1100	A PLGA core-containing hydrogel	1070:1100	A PLGA core-containing hydrogel	1070:1100	A PLGA core-containing hydrogel was then produced by ionically crosslinking the Ct.					
35738334	0	40	theme	self-eroding	67:78	arg1	chitosan					92:99	a self-eroding crosslinked chitosan	65:99	a self-eroding crosslinked chitosan	65:99	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	8	41	theme	experimental	1307:1318	arg1	factors					1320:1326	the following five experimental factors	1288:1326	the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent)	1288:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	9	42	theme	PTX	1662:1664	arg1	profiles					1674:1681	the TT and PTX release profiles	1651:1681	profiles	1674:1681	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	11	43	dep	similar	2174:2180	arg1	concomitant					2183:2193	concomitant	2183:2193	concomitant	2183:2193	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	9	44	theme	profiles	1674:1681	arg1	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	44	theme	profiles	1674:1681	arg1	f2					1644:1645	f2	1644:1645	f2	1644:1645	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	44	theme	profiles	1674:1681	arg1	factor					1636:1641	the similarity factor	1621:1641	the similarity factor	1621:1641	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	44	theme	profiles	1674:1681	arg1	f1					1613:1614	f1	1613:1614	f1	1613:1614	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	0	45	theme	PLGA	103:106	arg1	platform					108:115	PLGA platform	103:115	PLGA platform	103:115	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	1	46	theme	crosslinked	328:338	arg1	x-Ct					350:353	x-Ct	350:353	x-Ct	350:353	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	46	theme	crosslinked	328:338	arg1	chitosan					340:347	ionically crosslinked chitosan	318:347	ionically crosslinked chitosan (x-Ct)	318:354	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	8	47	theme	co-loaded	1519:1527	arg1	agent					1582:1586	the constitutional de-crosslinking agent	1547:1586	the constitutional de-crosslinking agent	1547:1586	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	47	theme	co-loaded	1519:1527	arg1	CaCl2					1540:1544	CaCl2	1540:1544	CaCl2 (the constitutional de-crosslinking agent)	1540:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	47	theme	co-loaded	1519:1527	arg1	amounts					1529:1535	the co-loaded amounts	1515:1535	the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent)	1515:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	12	48	theme	post-operative	2383:2396	arg1	application					2344:2354	An attractive medical application	2322:2354	An attractive medical application for such a device	2322:2372	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	48	theme	post-operative	2383:2396	arg1	treatment					2404:2412	post-operative local treatment	2383:2412	post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues	2383:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	49	theme	cancer	2565:2570	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	3	50	dep	PTX	759:761	arg1	soluble					777:783	soluble	777:783	soluble	777:783	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	2	51	theme	x-Ct	381:384	arg1	matrix					386:391	the x-Ct matrix	377:391	the x-Ct matrix	377:391	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	0	52	theme	release	18:24	arg1	rates					26:30	the release rates	14:30	the release rates of topotecan and paclitaxel	14:58	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	10	53	theme	processes	2085:2093	arg1	mechanisms					2059:2068	the exact mechanisms	2049:2068	the exact mechanisms of the release processes involved	2049:2102	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	11	54	theme	7 days	2220:2225	arg1	period					2210:2215	a period	2208:2215	a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant	2208:2319	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	3	55	theme	present	583:589	arg1	study					591:595	the present study	579:595	the present study	579:595	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	2	56	theme	erosion	361:367	arg1	rate					369:372	The erosion rate	357:372	The erosion rate of the x-Ct matrix	357:391	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	0	57	link	crosslinked	80:90	arg1	chitosan					92:99	a self-eroding crosslinked chitosan	65:99	a self-eroding crosslinked chitosan	65:99	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	10	58	theme	experimental	1840:1851	arg1	factors					1853:1859	the pre-determined experimental factors	1821:1859	the pre-determined experimental factors	1821:1859	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	9	59	theme	experimental	1712:1723	arg1	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	59	theme	experimental	1712:1723	arg1	responses					1725:1733	the experimental responses	1708:1733	the experimental responses	1708:1733	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	8	60	theme	b	1353:1353	arg1	amount					1369:1374	(b) its relative amount	1352:1374	(b) its relative amount in the formulation	1352:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	3	61	theme	modified	600:607	arg1	platform					609:616	a modified platform	598:616	a modified platform	598:616	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	1	62	theme	sodium	193:198	arg1	drugs					186:190	two model drugs	176:190	two model drugs	176:190	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	62	theme	sodium	193:198	arg1	salicylate					200:209	sodium salicylate	193:209	sodium salicylate (highly water-soluble)	193:232	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	3	63	theme	erosion	803:809	arg1	duration					811:818	the erosion duration	799:818	the erosion duration	799:818	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	3	64	theme	derived	828:834	arg1	release					848:854	the derived concomitant release	824:854	the derived concomitant release of the two drugs to several days	824:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	8	65	dep	concentration	1468:1480	arg1	d					1461:1461	d	1461:1461	d	1461:1461	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	66	theme	amount	1369:1374	arg1	e					1512:1512	e	1512:1512	e	1512:1512	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	66	theme	amount	1369:1374	arg1	type					1404:1407	the type	1400:1407	the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker	1400:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	66	theme	amount	1369:1374	arg1	type					1337:1340	the type	1333:1340	(a) the type of Ct and (b) its relative amount in the formulation	1329:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	67	from	Ct	1345:1346	arg1	formulation					1383:1393	the formulation	1379:1393	the formulation	1379:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	12	68	theme	malignant	2494:2502	arg1	tissues					2504:2510	malignant tissues	2494:2510	malignant tissues	2494:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	8	69	dep	factors	1320:1326	arg1	e					1512:1512	e	1512:1512	e	1512:1512	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	69	dep	factors	1320:1326	arg1	type					1404:1407	the type	1400:1407	the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker	1400:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	69	dep	factors	1320:1326	arg1	type					1337:1340	the type	1333:1340	(a) the type of Ct and (b) its relative amount in the formulation	1329:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	70	theme	following	1292:1300	arg1	factors					1320:1326	the following five experimental factors	1288:1326	the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent)	1288:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	10	71	theme	response	1926:1933	arg1	f2					1918:1919	f2	1918:1919	f2 (the response factors)	1918:1942	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	10	71	theme	response	1926:1933	arg1	factors					1935:1941	the response factors	1922:1941	the response factors	1922:1941	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	8	72	theme	constitutional	1551:1564	arg1	agent					1582:1586	the constitutional de-crosslinking agent	1547:1586	the constitutional de-crosslinking agent	1547:1586	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	72	theme	constitutional	1551:1564	arg1	CaCl2					1540:1544	CaCl2	1540:1544	CaCl2 (the constitutional de-crosslinking agent)	1540:1587	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	73	theme	crosslinker	1418:1428	arg1	e					1512:1512	e	1512:1512	e	1512:1512	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	73	theme	crosslinker	1418:1428	arg1	type					1404:1407	the type	1400:1407	the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker	1400:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	73	theme	crosslinker	1418:1428	arg1	type					1337:1340	the type	1333:1340	(a) the type of Ct and (b) its relative amount in the formulation	1329:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	5	74	theme	aqueous	1008:1014	arg1	solution					1016:1023	an aqueous solution	1005:1023	an aqueous solution of chitosan (Ct) in which PTX was dispersed	1005:1067	The sphere was then placed in an aqueous solution of chitosan (Ct) in which PTX was dispersed.					
35738334	2	75	theme	release	535:541	arg1	rates					543:547	the release rates	531:547	the release rates of the two drugs over 2 h	531:573	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	7	76	theme	Fractional	1235:1244	arg1	experiment					1256:1265	a statistically designed Fractional Factorial experiment	1210:1265	a statistically designed Fractional Factorial experiment	1210:1265	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	4	77	theme	calcium	949:955	arg1	CaCl2					967:971	CaCl2	967:971	CaCl2	967:971	TT was loaded into a PLGA sphere, which was co-loaded with calcium chloride (CaCl2).					
35738334	4	77	theme	calcium	949:955	arg1	chloride					957:964	calcium chloride	949:964	calcium chloride (CaCl2)	949:972	TT was loaded into a PLGA sphere, which was co-loaded with calcium chloride (CaCl2).					
35738334	8	78	theme	citric	1431:1436	arg1	acid					1438:1441	citric acid	1431:1441	citric acid	1431:1441	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	1	79	theme	previous	152:159	arg1	study					161:165	a previous study	150:165	a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct)	150:354	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	7	80	theme	Factorial	1246:1254	arg1	experiment					1256:1265	a statistically designed Fractional Factorial experiment	1210:1265	a statistically designed Fractional Factorial experiment	1210:1265	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	3	81	theme	several	876:882	arg1	days					884:887	several days	876:887	several days	876:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	10	82	from	effects	1810:1816	arg1	f2					1918:1919	f2	1918:1919	f2 (the response factors)	1918:1942	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	10	82	from	effects	1810:1816	arg1	factor					1910:1915	the similarity factor	1895:1915	the similarity factor	1895:1915	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	10	82	from	effects	1810:1816	arg1	f1					1887:1888	f1	1887:1888	f1	1887:1888	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	10	82	from	effects	1810:1816	arg1	factor					1879:1884	the difference factor	1864:1884	the difference factor	1864:1884	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	3	83	theme	drugs	867:871	arg1	release					848:854	the derived concomitant release	824:854	the derived concomitant release of the two drugs to several days	824:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	3	83	theme	drugs	867:871	arg1	duration					811:818	the erosion duration	799:818	the erosion duration	799:818	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	10	84	theme	collective	1799:1808	arg1	effects					1810:1816	the collective effects	1795:1816	the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors),	1795:1943	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	3	85	theme	release	664:670	arg1	rates					672:676	the release rates	660:676	the release rates of the two cytotoxic drugs	660:703	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	12	86	theme	localized	2438:2446	arg1	chemotherapy					2460:2471	localized combination chemotherapy	2438:2471	localized combination chemotherapy	2438:2471	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	2	87	theme	different	475:483	arg1	concentrations					485:498	different concentrations	475:498	different concentrations	475:498	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	9	88	theme	similarity	1625:1634	arg1	factor					1605:1610	The difference factor	1590:1610	The difference factor	1590:1610	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	9	88	theme	similarity	1625:1634	arg1	factor					1636:1641	the similarity factor	1621:1641	the similarity factor	1621:1641	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	3	89	dep	topotecan	706:714	arg1	TT					717:718	TT	717:718	TT	717:718	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	7	90	theme	formulation	1158:1168	arg1	section					1180:1186	The formulation screening section	1154:1186	The formulation screening section of the study	1154:1199	The formulation screening section of the study includes a statistically designed Fractional Factorial experiment.					
35738334	10	91	theme	computerized	1740:1751	arg1	models					1764:1769	The computerized prediction models	1736:1769	The computerized prediction models	1736:1769	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	8	92	from	formulation	1383:1393	arg1	e					1512:1512	e	1512:1512	e	1512:1512	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	92	from	formulation	1383:1393	arg1	type					1404:1407	the type	1400:1407	the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker	1400:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	92	from	formulation	1383:1393	arg1	type					1337:1340	the type	1333:1340	(a) the type of Ct and (b) its relative amount in the formulation	1329:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	3	93	dep	TT	717:718	arg1	soluble					734:740	soluble	734:740	soluble	734:740	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	12	94	theme	glioma	2573:2578	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	10	95	theme	fractional	1960:1969	arg1	design					1981:1986	a fractional factorial design	1958:1986	a fractional factorial design	1958:1986	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	8	96	dep	type	1404:1407	arg1	c					1397:1397	c	1397:1397	c	1397:1397	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	11	97	theme	novel	2262:2266	arg1	platform					2278:2285	the novel polymeric platform	2258:2285	the novel polymeric platform	2258:2285	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	97	theme	novel	2262:2266	arg1	implant					2313:2319	a multi-drug implant	2300:2319	a multi-drug implant	2300:2319	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	12	98	theme	peritoneal	2584:2593	arg1	carcinomatosis					2595:2608	peritoneal carcinomatosis	2584:2608	peritoneal carcinomatosis	2584:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	2	99	theme	chloride	436:443	arg1	de-crosslinker					456:469	de-crosslinker	456:469	de-crosslinker	456:469	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	2	99	theme	chloride	436:443	arg1	solutions					445:453	calcium chloride solutions	428:453	calcium chloride solutions (de-crosslinker) of different concentrations	428:498	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	10	100	theme	factors	1853:1859	arg1	effects					1810:1816	the collective effects	1795:1816	the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors),	1795:1943	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	3	101	theme	drugs	699:703	arg1	topotecan					706:714	topotecan	706:714	topotecan (TT, highly water soluble)	706:741	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	3	101	theme	drugs	699:703	arg1	paclitaxel					747:756	paclitaxel	747:756	paclitaxel (PTX, poorly water soluble)	747:784	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	3	101	theme	drugs	699:703	arg1	rates					672:676	the release rates	660:676	the release rates of the two cytotoxic drugs	660:703	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	0	102	theme	crosslinked	80:90	arg1	chitosan					92:99	a self-eroding crosslinked chitosan	65:99	a self-eroding crosslinked chitosan	65:99	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	3	103	dep	synchronize	648:658	arg1	prolong					791:797	prolong	791:797	to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days	641:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	3	103	dep	synchronize	648:658	arg1	a					645:645	a	645:645	a	645:645	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	8	104	theme	ionic	1489:1493	arg1	crosslinker					1495:1505	the ionic crosslinker	1485:1505	the ionic crosslinker	1485:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	10	105	theme	multifactorial	1992:2005	arg1	analysis					2007:2014	multifactorial analysis	1992:2014	multifactorial analysis	1992:2014	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	9	106	theme	release	1666:1672	arg1	profiles					1674:1681	the TT and PTX release profiles	1651:1681	profiles	1674:1681	The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses.					
35738334	1	107	link	crosslinked	328:338	arg1	x-Ct					350:353	x-Ct	350:353	x-Ct	350:353	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	1	107	link	crosslinked	328:338	arg1	chitosan					340:347	ionically crosslinked chitosan	318:347	ionically crosslinked chitosan (x-Ct)	318:354	This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct).					
35738334	2	108	from	immersion	415:423	arg1	de-crosslinker					456:469	de-crosslinker	456:469	de-crosslinker	456:469	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	2	108	from	immersion	415:423	arg1	solutions					445:453	calcium chloride solutions	428:453	calcium chloride solutions (de-crosslinker) of different concentrations	428:498	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	10	109	theme	similarity	1899:1908	arg1	f2					1918:1919	f2	1918:1919	f2 (the response factors)	1918:1942	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	10	109	theme	similarity	1899:1908	arg1	factor					1910:1915	the similarity factor	1895:1915	the similarity factor	1895:1915	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	12	110	theme	cancer	2549:2554	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	2	111	theme	matrix	386:391	arg1	rate					369:372	The erosion rate	357:372	The erosion rate of the x-Ct matrix	357:391	The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h.					
35738334	12	112	theme	ovarian	2557:2563	arg1	cancer					2565:2570	ovarian cancer	2557:2570	ovarian cancer	2557:2570	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	11	113	theme	final	2109:2113	arg1	platform					2125:2132	The final composite platform	2105:2132	The final composite platform	2105:2132	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	113	theme	final	2109:2113	arg1	capable					2138:2144	capable	2138:2144	capable	2138:2144	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	10	114	theme	difference	1868:1877	arg1	factor					1879:1884	the difference factor	1864:1884	the difference factor	1864:1884	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	12	115	theme	local	2398:2402	arg1	application					2344:2354	An attractive medical application	2322:2354	An attractive medical application for such a device	2322:2372	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	12	115	theme	local	2398:2402	arg1	treatment					2404:2412	post-operative local treatment	2383:2412	post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues	2383:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	3	116	link	derived	828:834	arg1	release					848:854	the derived concomitant release	824:854	the derived concomitant release of the two drugs to several days	824:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	12	117	theme	surgical	2520:2527	arg1	treatment					2529:2537	the surgical treatment	2516:2537	the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis	2516:2608	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	0	118	theme	topotecan	35:43	arg1	rates					26:30	the release rates	14:30	the release rates of topotecan and paclitaxel	14:58	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	10	119	theme	release	2077:2083	arg1	processes					2085:2093	the release processes	2073:2093	the release processes involved	2073:2102	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	0	120	theme	paclitaxel	49:58	arg1	rates					26:30	the release rates	14:30	the release rates of topotecan and paclitaxel	14:58	Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.					
35738334	11	121	theme	composite	2115:2123	arg1	platform					2125:2132	The final composite platform	2105:2132	The final composite platform	2105:2132	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	11	121	theme	composite	2115:2123	arg1	capable					2138:2144	capable	2138:2144	capable	2138:2144	The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant.					
35738334	12	122	theme	tissues	2504:2510	arg1	removal					2483:2489	the removal	2479:2489	the removal of malignant tissues	2479:2510	An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.					
35738334	3	123	dep	paclitaxel	747:756	arg1	PTX					759:761	PTX	759:761	PTX	759:761	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	8	124	theme	relative	1360:1367	arg1	amount					1369:1374	(b) its relative amount	1352:1374	(b) its relative amount in the formulation	1352:1393	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	10	125	theme	pre-determined	1825:1838	arg1	factors					1853:1859	the pre-determined experimental factors	1821:1859	the pre-determined experimental factors	1821:1859	The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved.					
35738334	5	126	theme	chitosan	1028:1035	arg1	solution					1016:1023	an aqueous solution	1005:1023	an aqueous solution of chitosan (Ct) in which PTX was dispersed	1005:1067	The sphere was then placed in an aqueous solution of chitosan (Ct) in which PTX was dispersed.					
35738334	3	127	theme	concomitant	836:846	arg1	release					848:854	the derived concomitant release	824:854	the derived concomitant release of the two drugs to several days	824:887	In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days.					
35738334	4	128	theme	PLGA	911:914	arg1	sphere					916:921	a PLGA sphere	909:921	a PLGA sphere	909:921	TT was loaded into a PLGA sphere, which was co-loaded with calcium chloride (CaCl2).					
35738334	8	129	theme	ionic	1412:1416	arg1	concentration					1468:1480	the concentration	1464:1480	(d) the concentration of the ionic crosslinker	1460:1505	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
35738334	8	129	theme	ionic	1412:1416	arg1	crosslinker					1418:1428	ionic crosslinker	1412:1428	ionic crosslinker (citric acid or oxalic acid)	1412:1457	It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent).					
36382383	4	0	theme	free	869:872	arg1	saccharide					874:883	free saccharide	869:883	free saccharide	869:883	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	1	theme	structural	709:718	arg1	composition					720:730	the structural composition	705:730	the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	705:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	6	2	theme	AOAC	986:989	arg1	methods					991:997	both AOAC methods	981:997	both AOAC methods	981:997	For oats, both AOAC methods gave similar results.					
36382383	10	3	theme	classical	1609:1617	arg1	insoluble					1655:1663	insoluble	1655:1663	insoluble	1655:1663	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	10	3	theme	classical	1609:1617	arg1	determinations					1620:1633	"classical" determinations	1608:1633	"classical" determinations such as soluble and insoluble fiber	1608:1669	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	10	3	theme	classical	1609:1617	arg1	soluble					1643:1649	soluble	1643:1649	soluble	1643:1649	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	9	4	theme	starch	1422:1427	arg1	content					1404:1410	the resistant starch content	1383:1410	the resistant starch content of potato starch and the different starch digestion conditions used in each method	1383:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	4	5	theme	glycosidic	845:854	arg1	linkage					856:862	glycosidic linkage	845:862	glycosidic linkage	845:862	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	3	6	theme	food	507:510	arg1	analysis					525:532	food carbohydrate analysis	507:532	food carbohydrate analysis	507:532	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	9	7	theme	digestion	1454:1462	arg1	conditions					1464:1473	the different starch digestion conditions	1433:1473	the different starch digestion conditions used in each method	1433:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	7	8	with	β-glucan	1183:1190	arg1	arabinogalactan					1215:1229	arabinogalactan	1215:1229	arabinogalactan	1215:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	7	8	with	β-glucan	1183:1190	arg1	amounts					1204:1210	small amounts	1198:1210	small amounts of arabinogalactan	1198:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	4	9	from	methods	787:793	arg1	fractions					763:771	soluble and insoluble fiber fractions	735:771	soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	735:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	9	from	methods	787:793	arg1	composition					720:730	the structural composition	705:730	the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	705:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	10	theme	AOAC	782:785	arg1	methods					787:793	two AOAC methods	778:793	two AOAC methods (991.43 and 2017.16)	778:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	11	theme	fractions	763:771	arg1	composition					720:730	the structural composition	705:730	the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	705:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	9	12	theme	resistant	1387:1395	arg1	content					1404:1410	the resistant starch content	1383:1410	the resistant starch content of potato starch and the different starch digestion conditions used in each method	1383:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	4	13	theme	fiber	757:761	arg1	fractions					763:771	soluble and insoluble fiber fractions	735:771	soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	735:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	14	theme	saccharide	874:883	arg1	level					885:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	5	15	theme	proof-of-concept	923:938	arg1	study					940:944	this proof-of-concept study	918:944	this proof-of-concept study	918:944	Two foods were chosen for this proof-of-concept study: oats and potato starch.					
36382383	7	16	theme	small	1198:1202	arg1	arabinogalactan					1215:1229	arabinogalactan	1215:1229	arabinogalactan	1215:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	7	16	theme	small	1198:1202	arg1	amounts					1204:1210	small amounts	1198:1210	small amounts of arabinogalactan	1198:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	4	17	theme	soluble	735:741	arg1	fractions					763:771	soluble and insoluble fiber fractions	735:771	soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	735:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	0	18	from	Methods	51:57	arg1	Characterization					15:30	Multi-Glycomic Characterization	0:30	Multi-Glycomic Characterization of Fiber from AOAC Methods	0:57	Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures.					
36382383	1	19	from	determinant	277:287	arg1	interaction					297:307	this interaction	292:307	this interaction	292:307	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	4	20	theme	LC-MS	639:643	arg1	methods					645:651	rapid-throughput LC-MS methods	622:651	rapid-throughput LC-MS methods	622:651	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	8	21	theme	soluble	1311:1317	arg1	fractions					1325:1333	the soluble fiber fractions	1307:1333	the soluble fiber fractions	1307:1333	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	9	22	theme	potato	1415:1420	arg1	starch					1422:1427	potato starch	1415:1427	potato starch	1415:1427	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	4	23	theme	novel	666:670	arg1	pipeline					683:690	a novel analytical pipeline	664:690	a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level	664:889	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	9	24	theme	starch	1397:1402	arg1	content					1404:1410	the resistant starch content	1383:1410	the resistant starch content of potato starch and the different starch digestion conditions used in each method	1383:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	11	25	theme	fiber	1746:1750	arg1	determinations					1752:1765	gravimetric fiber determinations	1734:1765	gravimetric fiber determinations with their constituent structures	1734:1799	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	6	26	theme	similar	1004:1010	arg1	results					1012:1018	similar results	1004:1018	similar results	1004:1018	For oats, both AOAC methods gave similar results.					
36382383	1	27	theme	healthy	164:170	arg1	diet					172:175	a healthy diet	162:175	a healthy diet	162:175	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	7	28	theme	soluble	1146:1152	arg1	fiber					1154:1158	soluble fiber	1146:1158	soluble fiber	1146:1158	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	11	29	theme	microbiome	1822:1831	arg1	studies					1856:1862	gut microbiome and clinical nutrition studies	1818:1862	gut microbiome and clinical nutrition studies	1818:1862	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	1	30	theme	Dietary	96:102	arg1	fiber					104:108	Dietary fiber	96:108	Dietary fiber	96:108	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	1	30	theme	Dietary	96:102	arg1	component					149:157	an essential component	136:157	an essential component of a healthy diet	136:175	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	4	31	dep	methods	787:793	arg1	2017.16					807:813	2017.16	807:813	2017.16	807:813	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	31	dep	methods	787:793	arg1	991.43					796:801	991.43	796:801	991.43	796:801	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	1	32	theme	diet	172:175	arg1	fiber					104:108	Dietary fiber	96:108	Dietary fiber	96:108	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	1	32	theme	diet	172:175	arg1	component					149:157	an essential component	136:157	an essential component of a healthy diet	136:175	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	0	33	theme	Multi-Glycomic	0:13	arg1	Characterization					15:30	Multi-Glycomic Characterization	0:30	Multi-Glycomic Characterization of Fiber from AOAC Methods	0:57	Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures.					
36382383	11	34	theme	constituent	1778:1788	arg1	structures					1790:1799	their constituent structures	1772:1799	their constituent structures	1772:1799	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	4	35	theme	linkage	856:862	arg1	level					885:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	4	36	theme	insoluble	747:755	arg1	fractions					763:771	soluble and insoluble fiber fractions	735:771	soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16)	735:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	2	37	theme	gut	352:354	arg1	microbiome					356:365	the gut microbiome	348:365	the gut microbiome	348:365	Further, fiber is now known to impact the gut microbiome in a structure-specific manner, conferring differential bioactivities to these specific structures.					
36382383	0	38	theme	Fiber	35:39	arg1	Characterization					15:30	Multi-Glycomic Characterization	0:30	Multi-Glycomic Characterization of Fiber from AOAC Methods	0:57	Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures.					
36382383	1	39	theme	prime	271:275	arg1	determinant					277:287	a prime determinant	269:287	a prime determinant in this interaction	269:307	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	1	39	theme	prime	271:275	arg1	fiber					260:264	fiber	260:264	fiber	260:264	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	4	40	used	utilized	613:620	arg2	we					610:611	we	610:611	we	610:611	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	2	41	from	impact	341:346	arg1	manner					391:396	a structure-specific manner	370:396	a structure-specific manner	370:396	Further, fiber is now known to impact the gut microbiome in a structure-specific manner, conferring differential bioactivities to these specific structures.					
36382383	3	42	theme	important	554:562	arg1	information					575:585	this important structural information	549:585	this important structural information	549:585	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	2	43	theme	differential	410:421	arg1	bioactivities					423:435	differential bioactivities	410:435	differential bioactivities	410:435	Further, fiber is now known to impact the gut microbiome in a structure-specific manner, conferring differential bioactivities to these specific structures.					
36382383	3	44	theme	structural	564:573	arg1	information					575:585	this important structural information	549:585	this important structural information	549:585	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	1	45	theme	recent	182:187	arg1	investigations					189:202	recent investigations	182:202	recent investigations into the gut microbiome-health paradigm	182:242	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	0	46	theme	AOAC	46:49	arg1	Methods					51:57	AOAC Methods	46:57	AOAC Methods	46:57	Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures.					
36382383	11	47	theme	nutrition	1846:1854	arg1	studies					1856:1862	gut microbiome and clinical nutrition studies	1818:1862	gut microbiome and clinical nutrition studies	1818:1862	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	11	48	theme	clinical	1837:1844	arg1	nutrition					1846:1854	clinical nutrition	1837:1854	clinical nutrition	1837:1854	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	9	49	theme	different	1437:1445	arg1	conditions					1464:1473	the different starch digestion conditions	1433:1473	the different starch digestion conditions used in each method	1433:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	4	50	theme	analytical	672:681	arg1	pipeline					683:690	a novel analytical pipeline	664:690	a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level	664:889	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	8	51	theme	potato	1240:1245	arg1	starch					1247:1252	raw potato starch	1236:1252	raw potato starch	1236:1252	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	10	52	theme	"	1618:1618	arg1	insoluble					1655:1663	insoluble	1655:1663	insoluble	1655:1663	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	10	52	theme	"	1618:1618	arg1	determinations					1620:1633	"classical" determinations	1608:1633	"classical" determinations such as soluble and insoluble fiber	1608:1669	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	10	52	theme	"	1618:1618	arg1	soluble					1643:1649	soluble	1643:1649	soluble	1643:1649	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	9	53	theme	starch	1447:1452	arg1	conditions					1464:1473	the different starch digestion conditions	1433:1473	the different starch digestion conditions used in each method	1433:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	4	54	theme	rapid-throughput	622:637	arg1	methods					645:651	rapid-throughput LC-MS methods	622:651	rapid-throughput LC-MS methods	622:651	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	2	55	theme	structure-specific	372:389	arg1	manner					391:396	a structure-specific manner	370:396	a structure-specific manner	370:396	Further, fiber is now known to impact the gut microbiome in a structure-specific manner, conferring differential bioactivities to these specific structures.					
36382383	10	56	theme	dietary	1578:1584	arg1	fiber					1586:1590	dietary fiber	1578:1590	dietary fiber	1578:1590	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	11	57	theme	gut	1818:1820	arg1	microbiome					1822:1831	gut microbiome	1818:1831	gut microbiome	1818:1831	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	4	58	theme	monosaccharide	829:842	arg1	level					885:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	the total monosaccharide, glycosidic linkage, and free saccharide level	819:889	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	8	59	theme	fiber	1319:1323	arg1	fractions					1325:1333	the soluble fiber fractions	1307:1333	the soluble fiber fractions	1307:1333	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	3	60	theme	analytical	484:493	arg1	methods					495:501	current analytical methods	476:501	current analytical methods for food carbohydrate analysis	476:532	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	2	61	theme	specific	446:453	arg1	structures					455:464	these specific structures	440:464	these specific structures	440:464	Further, fiber is now known to impact the gut microbiome in a structure-specific manner, conferring differential bioactivities to these specific structures.					
36382383	11	62	theme	gravimetric	1734:1744	arg1	determinations					1752:1765	gravimetric fiber determinations	1734:1765	gravimetric fiber determinations with their constituent structures	1734:1799	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	4	63	theme	total	823:827	arg1	monosaccharide					829:842	total monosaccharide	823:842	total monosaccharide	823:842	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	9	64	theme	conditions	1464:1473	arg1	content					1404:1410	the resistant starch content	1383:1410	the resistant starch content of potato starch and the different starch digestion conditions used in each method	1383:1493	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	7	65	theme	arabinogalactan	1215:1229	arg1	arabinogalactan					1215:1229	arabinogalactan	1215:1229	arabinogalactan	1215:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	7	65	theme	arabinogalactan	1215:1229	arg1	amounts					1204:1210	small amounts	1198:1210	small amounts of arabinogalactan	1198:1229	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	11	66	with	determinations	1752:1765	arg1	structures					1790:1799	their constituent structures	1772:1799	their constituent structures	1772:1799	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36382383	8	67	theme	AOAC	1260:1263	arg1	method					1265:1270	each AOAC method	1255:1270	each AOAC method	1255:1270	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	9	68	theme	observed	1342:1349	arg1	differences					1351:1361	These observed differences	1336:1361	These observed differences	1336:1361	These observed differences are attributable to the resistant starch content of potato starch and the different starch digestion conditions used in each method.					
36382383	7	69	theme	Insoluble	1021:1029	arg1	fiber					1031:1035	Insoluble fiber	1021:1035	Insoluble fiber	1021:1035	Insoluble fiber was found to be comprised of linkages corresponding to β-glucan, arabinoxylan, xyloglucan, and mannan, while soluble fiber was found to be mostly β-glucan, with small amounts of arabinogalactan.					
36382383	5	70	theme	potato	956:961	arg1	starch					963:968	potato starch	956:968	potato starch	956:968	Two foods were chosen for this proof-of-concept study: oats and potato starch.					
36382383	3	71	theme	current	476:482	arg1	methods					495:501	current analytical methods	476:501	current analytical methods for food carbohydrate analysis	476:532	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	8	72	theme	different	1286:1294	arg1	results					1296:1302	markedly different results	1277:1302	markedly different results	1277:1302	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	1	73	theme	gut	213:215	arg1	paradigm					235:242	the gut microbiome-health paradigm	209:242	the gut microbiome-health paradigm	209:242	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	0	74	theme	Carbohydrate	71:82	arg1	Structures					84:93	the Carbohydrate Structures	67:93	the Carbohydrate Structures	67:93	Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures.					
36382383	8	75	theme	raw	1236:1238	arg1	starch					1247:1252	raw potato starch	1236:1252	raw potato starch	1236:1252	For raw potato starch, each AOAC method gave markedly different results in the soluble fiber fractions.					
36382383	10	76	theme	complex	1544:1550	arg1	structures					1552:1561	the complex structures	1540:1561	the complex structures present within dietary fiber	1540:1590	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	3	77	theme	carbohydrate	512:523	arg1	analysis					525:532	food carbohydrate analysis	507:532	food carbohydrate analysis	507:532	However, current analytical methods for food carbohydrate analysis do not capture this important structural information.					
36382383	4	78	from	composition	720:730	arg1	methods					787:793	two AOAC methods	778:793	two AOAC methods (991.43 and 2017.16)	778:814	To address this need, we utilized rapid-throughput LC-MS methods to develop a novel analytical pipeline to determine the structural composition of soluble and insoluble fiber fractions from two AOAC methods (991.43 and 2017.16) at the total monosaccharide, glycosidic linkage, and free saccharide level.					
36382383	1	79	theme	microbiome-health	217:233	arg1	paradigm					235:242	the gut microbiome-health paradigm	209:242	the gut microbiome-health paradigm	209:242	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	10	80	theme	present	1563:1569	arg1	structures					1552:1561	the complex structures	1540:1561	the complex structures present within dietary fiber	1540:1590	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	10	81	dep	soluble	1643:1649	arg1	fiber					1665:1669	fiber	1665:1669	fiber	1665:1669	Together, these tools are a means to obtain the complex structures present within dietary fiber while retaining "classical" determinations such as soluble and insoluble fiber.					
36382383	1	82	theme	essential	139:147	arg1	fiber					104:108	Dietary fiber	96:108	Dietary fiber	96:108	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	1	82	theme	essential	139:147	arg1	component					149:157	an essential component	136:157	an essential component of a healthy diet	136:175	Dietary fiber has long been known to be an essential component of a healthy diet, and recent investigations into the gut microbiome-health paradigm have identified fiber as a prime determinant in this interaction.					
36382383	11	83	theme	analytical	1702:1711	arg1	framework					1713:1721	an analytical framework	1699:1721	an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies	1699:1862	These efforts will provide an analytical framework to connect gravimetric fiber determinations with their constituent structures to better inform gut microbiome and clinical nutrition studies.					
36694053	9	0	contain	have	1280:1283	arg1	SCF					1266:1268	SCF	1266:1268	SCF	1266:1268	SCF tended to have the greatest effect on propionate production.					
36694053	9	0	contain	have	1280:1283	arg2	effect					1298:1303	the greatest effect	1285:1303	the greatest effect	1285:1303	SCF tended to have the greatest effect on propionate production.					
36694053	9	1	theme	greatest	1289:1296	arg1	effect					1298:1303	the greatest effect	1285:1303	the greatest effect	1285:1303	SCF tended to have the greatest effect on propionate production.					
36694053	2	2	theme	model	264:268	arg1	simulator					199:207	an in vitro mucosal simulator	179:207	an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model	179:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	4	3	from	responses	818:826	arg1	lipopolysaccharide					831:848	lipopolysaccharide	831:848	lipopolysaccharide	831:848	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	4	3	from	responses	818:826	arg1	barrier					793:799	the intestinal epithelial cell barrier	762:799	the intestinal epithelial cell barrier	762:799	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	4	4	theme	M-SHIME®	705:712	arg1	supernatants					714:725	M-SHIME® supernatants	705:725	M-SHIME® supernatants	705:725	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	10	5	dep	mechanisms	1453:1462	arg1	behind					1464:1469	behind	1464:1469	behind the observed prebiotic effects	1464:1500	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	2	6	theme	M-SHIME®	254:261	arg1	model					264:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	4	7	theme	inflammatory	805:816	arg1	responses					818:826	inflammatory responses	805:826	inflammatory responses in lipopolysaccharide	805:848	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	8	8	theme	SCF	1119:1121	arg1	treatment					1123:1131	SCF treatment	1119:1131	SCF treatment	1119:1131	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	9	theme	[70	528:530	arg1	years					532:536	elderly [70 years	520:536	elderly [70 years	520:536	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	10	10	theme	prebiotic	1484:1492	arg1	effects					1494:1500	the observed prebiotic effects	1471:1500	the observed prebiotic effects	1471:1500	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	4	11	theme	epithelial	777:786	arg1	barrier					793:799	the intestinal epithelial cell barrier	762:799	the intestinal epithelial cell barrier	762:799	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	8	12	theme	Bifidobacterial	1193:1207	arg1	production					1236:1245	increased SCFA production	1221:1245	increased SCFA production in all age groups	1221:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	8	12	theme	Bifidobacterial	1193:1207	arg1	expansion					1149:1157	the expansion	1145:1157	the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial	1145:1207	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	13	theme	ecosystem	243:251	arg1	model					264:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	6	14	theme	acid	907:910	arg1	production					919:928	short-chain fatty acid (SCFA) production	889:928	short-chain fatty acid (SCFA) production	889:928	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	0	15	theme	M-SHIME®	57:64	arg1	Ecosystems					80:89	M-SHIME® Gut Microbial Ecosystems	57:89	M-SHIME® Gut Microbial Ecosystems	57:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	4	16	from	effect	752:757	arg1	lipopolysaccharide					831:848	lipopolysaccharide	831:848	lipopolysaccharide	831:848	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	4	16	from	effect	752:757	arg1	barrier					793:799	the intestinal epithelial cell barrier	762:799	the intestinal epithelial cell barrier	762:799	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	2	17	theme	intestinal	222:231	arg1	model					264:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	1	18	theme	prebiotic	134:142	arg1	effects					144:150	prebiotic effects	134:150	prebiotic effects	134:150	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	2	19	from	effects	275:281	arg1	interactions					380:391	host-microbiome interactions	364:391	host-microbiome interactions	364:391	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	19	from	effects	275:281	arg1	composition					322:332	colonic microbiota composition	303:332	colonic microbiota composition	303:332	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	6	20	theme	short-chain	889:899	arg1	SCFA					913:916	SCFA	913:916	SCFA	913:916	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	6	20	theme	short-chain	889:899	arg1	acid					907:910	short-chain fatty acid	889:910	short-chain fatty acid (SCFA) production	889:928	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	0	21	from	Effects	24:30	arg1	Ecosystems					80:89	M-SHIME® Gut Microbial Ecosystems	57:89	M-SHIME® Gut Microbial Ecosystems	57:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	0	22	theme	Microbial	70:78	arg1	Ecosystems					80:89	M-SHIME® Gut Microbial Ecosystems	57:89	M-SHIME® Gut Microbial Ecosystems	57:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	2	23	theme	adult	492:496	arg1	years					505:509	adult [18-45 years	492:509	adult [18-45 years	492:509	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	8	24	theme	SCFA	1231:1234	arg1	production					1236:1245	increased SCFA production	1221:1245	increased SCFA production in all age groups	1221:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	25	dep	ages	461:464	arg1	n = 4					485:489	n = 4	485:489	n = 4	485:489	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	25	dep	ages	461:464	arg1	n = 1					540:544	n = 1	540:544	n = 1	540:544	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	25	dep	ages	461:464	arg1	n = 2					513:517	n = 2	513:517	n = 2	513:517	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	10	26	theme	prebiotic	1362:1370	arg1	potential					1372:1380	the prebiotic potential	1358:1380	the prebiotic potential of SCF in babies, adults, and the elderly	1358:1422	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	3	27	dep	supplemented	606:617	arg1	baby					635:638	baby	635:638	baby	635:638	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	5	28	theme	-stimulated	856:866	arg1	cells					868:872	(LPS)-stimulated cells	851:872	(LPS)-stimulated cells	851:872	(LPS)-stimulated cells.					
36694053	8	29	theme	age	1254:1256	arg1	groups					1258:1263	all age groups	1250:1263	all age groups	1250:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	0	30	theme	Age-Dependent	0:12	arg1	Effects					24:30	Age-Dependent Prebiotic Effects	0:30	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems	0:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	1	31	theme	Soluble	92:98	arg1	SCF					112:114	SCF	112:114	SCF	112:114	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	1	31	theme	Soluble	92:98	arg1	fiber					105:109	Soluble corn fiber	92:109	Soluble corn fiber (SCF)	92:115	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	6	32	theme	microbial	934:942	arg1	composition					954:964	microbial community composition	934:964	microbial community composition	934:964	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	2	33	theme	fecal	414:418	arg1	samples					420:426	fecal samples	414:426	fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	414:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	7	34	theme	treated	1042:1048	arg1	vessels					1050:1056	SCF treated vessels	1038:1056	SCF treated vessels	1038:1056	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	9	35	theme	propionate	1308:1317	arg1	production					1319:1328	propionate production	1308:1328	propionate production	1308:1328	SCF tended to have the greatest effect on propionate production.					
36694053	3	36	dep	baby	635:638	arg1	1.5					641:643	1.5	641:643	1.5	641:643	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	adult					661:665	adult	661:665	adult	661:665	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	elderly					686:692	elderly	686:692	elderly	686:692	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	3					668:668	3	668:668	3	668:668	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	3					646:646	3	646:646	3	646:646	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	8.5 g/d					695:701	8.5 g/d	695:701	8.5 g/d	695:701	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	3	36	dep	baby	635:638	arg1	4.5 g/d					652:658	4.5 g/d	652:658	4.5 g/d	652:658	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	0	37	theme	Soluble	35:41	arg1	Fiber					48:52	Soluble Corn Fiber	35:52	Soluble Corn Fiber	35:52	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	2	38	theme	different	451:459	arg1	years					477:481	baby [≤ 2 years	467:481	baby [≤ 2 years	467:481	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	38	theme	different	451:459	arg1	ages					461:464	different ages	451:464	different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	451:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	3	39	theme	treatment	566:574	arg1	period					576:581	the 3-week treatment period	555:581	the 3-week treatment period	555:581	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	2	40	theme	microbiota	311:320	arg1	composition					322:332	colonic microbiota composition	303:332	colonic microbiota composition	303:332	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	0	41	theme	Fiber	48:52	arg1	Effects					24:30	Age-Dependent Prebiotic Effects	0:30	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems	0:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	8	42	from	production	1236:1245	arg1	groups					1258:1263	all age groups	1250:1263	all age groups	1250:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	43	dep	n = 2	513:517	arg1	years					532:536	elderly [70 years	520:536	elderly [70 years	520:536	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	7	44	theme	adult	997:1001	arg1	models					1003:1008	the baby and adult models	984:1008	models	1003:1008	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	7	45	theme	baby	988:991	arg1	models					1003:1008	the baby and adult models	984:1008	models	1003:1008	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	1	46	theme	clinical	155:162	arg1	studies					164:170	clinical studies	155:170	clinical studies	155:170	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	7	47	theme	M-SHIME®	1011:1018	arg1	supernatants					1020:1031	M-SHIME® supernatants	1011:1031	M-SHIME® supernatants from SCF treated vessels	1011:1056	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	10	48	theme	observed	1475:1482	arg1	effects					1494:1500	the observed prebiotic effects	1471:1500	the observed prebiotic effects	1471:1500	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	2	49	theme	SCF	286:288	arg1	treatment					290:298	SCF treatment	286:298	SCF treatment	286:298	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	4	50	theme	cell	788:791	arg1	barrier					793:799	the intestinal epithelial cell barrier	762:799	the intestinal epithelial cell barrier	762:799	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	2	51	theme	human	216:220	arg1	model					264:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	52	theme	[18-45	498:503	arg1	years					505:509	adult [18-45 years	492:509	adult [18-45 years	492:509	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	8	53	theme	Bacteroidetes	1162:1174	arg1	production					1236:1245	increased SCFA production	1221:1245	increased SCFA production in all age groups	1221:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	8	53	theme	Bacteroidetes	1162:1174	arg1	expansion					1149:1157	the expansion	1145:1157	the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial	1145:1207	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	54	theme	elderly	520:526	arg1	years					532:536	elderly [70 years	520:536	elderly [70 years	520:536	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	8	55	theme	Firmicutes	1177:1186	arg1	production					1236:1245	increased SCFA production	1221:1245	increased SCFA production in all age groups	1221:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	8	55	theme	Firmicutes	1177:1186	arg1	expansion					1149:1157	the expansion	1145:1157	the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial	1145:1207	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	4	56	theme	intestinal	766:775	arg1	barrier					793:799	the intestinal epithelial cell barrier	762:799	the intestinal epithelial cell barrier	762:799	M-SHIME® supernatants were evaluated for their effect on the intestinal epithelial cell barrier and inflammatory responses in lipopolysaccharide.					
36694053	0	57	theme	Gut	66:68	arg1	Ecosystems					80:89	M-SHIME® Gut Microbial Ecosystems	57:89	M-SHIME® Gut Microbial Ecosystems	57:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	2	58	theme	microbial	233:241	arg1	model					264:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	the human intestinal microbial ecosystem (M-SHIME®) model	212:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	10	59	from	potential	1372:1380	arg1	elderly					1416:1422	elderly	1416:1422	elderly	1416:1422	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	10	59	from	potential	1372:1380	arg1	adults					1400:1405	adults	1400:1405	adults	1400:1405	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	10	59	from	potential	1372:1380	arg1	babies					1392:1397	babies	1392:1397	babies	1392:1397	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	6	60	theme	fatty	901:905	arg1	SCFA					913:916	SCFA	913:916	SCFA	913:916	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	6	60	theme	fatty	901:905	arg1	acid					907:910	short-chain fatty acid	889:910	short-chain fatty acid (SCFA) production	889:928	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	7	61	theme	LPS-induced	1099:1109	arg1	damage					1111:1116	LPS-induced damage	1099:1116	LPS-induced damage	1099:1116	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	8	62	from	expansion	1149:1157	arg1	groups					1258:1263	all age groups	1250:1263	all age groups	1250:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	2	63	theme	baby	467:470	arg1	years					477:481	baby [≤ 2 years	467:481	baby [≤ 2 years	467:481	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	63	theme	baby	467:470	arg1	ages					461:464	different ages	451:464	different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	451:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	64	from	donors	441:446	arg1	samples					420:426	fecal samples	414:426	fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	414:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	65	theme	in	182:183	arg1	simulator					199:207	an in vitro mucosal simulator	179:207	an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model	179:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	8	66	theme	increased	1221:1229	arg1	production					1236:1245	increased SCFA production	1221:1245	increased SCFA production in all age groups	1221:1263	SCF treatment resulted in the expansion of Bacteroidetes, Firmicutes, and Bifidobacterial, as well as increased SCFA production in all age groups.					
36694053	7	67	theme	Caco-2	1068:1073	arg1	integrity					1084:1092	Caco-2 membrane integrity	1068:1092	Caco-2 membrane integrity	1068:1092	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	7	68	from	vessels	1050:1056	arg1	supernatants					1020:1031	M-SHIME® supernatants	1011:1031	M-SHIME® supernatants from SCF treated vessels	1011:1056	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	2	69	theme	host-microbiome	364:378	arg1	interactions					380:391	host-microbiome interactions	364:391	host-microbiome interactions	364:391	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	0	70	theme	Prebiotic	14:22	arg1	Effects					24:30	Age-Dependent Prebiotic Effects	0:30	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems	0:89	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	6	71	theme	community	944:952	arg1	composition					954:964	microbial community composition	934:964	microbial community composition	934:964	Additionally, short-chain fatty acid (SCFA) production and microbial community composition were assessed.					
36694053	2	72	theme	healthy	433:439	arg1	donors					441:446	healthy donors	433:446	healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	433:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	7	73	theme	SCF	1038:1040	arg1	vessels					1050:1056	SCF treated vessels	1038:1056	SCF treated vessels	1038:1056	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	2	74	dep	n = 4	485:489	arg1	years					505:509	adult [18-45 years	492:509	adult [18-45 years	492:509	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	1	75	theme	corn	100:103	arg1	SCF					112:114	SCF	112:114	SCF	112:114	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	1	75	theme	corn	100:103	arg1	fiber					105:109	Soluble corn fiber	92:109	Soluble corn fiber (SCF)	92:115	Soluble corn fiber (SCF) has demonstrated prebiotic effects in clinical studies.					
36694053	10	76	theme	SCF	1385:1387	arg1	potential					1372:1380	the prebiotic potential	1358:1380	the prebiotic potential of SCF in babies, adults, and the elderly	1358:1422	These findings demonstrate the prebiotic potential of SCF in babies, adults, and the elderly and provide insight into the mechanisms behind the observed prebiotic effects.					
36694053	0	77	theme	Corn	43:46	arg1	Fiber					48:52	Soluble Corn Fiber	35:52	Soluble Corn Fiber	35:52	Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems.					
36694053	2	78	theme	ages	461:464	arg1	donors					441:446	healthy donors	433:446	healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1)	433:545	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	3	79	theme	3-week	559:564	arg1	period					576:581	the 3-week treatment period	555:581	the 3-week treatment period	555:581	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	7	80	theme	membrane	1075:1082	arg1	integrity					1084:1092	Caco-2 membrane integrity	1068:1092	Caco-2 membrane integrity	1068:1092	In the baby and adult models, M-SHIME® supernatants from SCF treated vessels protected Caco-2 membrane integrity from LPS-induced damage.					
36694053	2	81	theme	mucosal	191:197	arg1	simulator					199:207	an in vitro mucosal simulator	179:207	an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model	179:268	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	82	theme	colonic	303:309	arg1	composition					322:332	colonic microbiota composition	303:332	colonic microbiota composition	303:332	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	83	dep	in	182:183	arg1	vitro					185:189	vitro	185:189	vitro	185:189	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	3	84	theme	M-SHIME®	584:591	arg1	systems					593:599	M-SHIME® systems	584:599	M-SHIME® systems	584:599	During the 3-week treatment period, M-SHIME® systems were supplemented with SCF daily (baby, 1.5, 3, or 4.5 g/d; adult, 3 or 8.5 g/d; and elderly, 8.5 g/d).					
36694053	2	85	theme	treatment	290:298	arg1	effects					275:281	the effects	271:281	the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions	271:391	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36694053	2	86	theme	metabolic	338:346	arg1	activity					348:355	metabolic activity	338:355	metabolic activity	338:355	Using an in vitro mucosal simulator of the human intestinal microbial ecosystem (M-SHIME®) model, the effects of SCF treatment on colonic microbiota composition and metabolic activity and on host-microbiome interactions were evaluated using fecal samples from healthy donors of different ages (baby [≤ 2 years], n = 4; adult [18-45 years], n = 2; elderly [70 years], n = 1).					
36710550	10	0	theme	factor	1527:1532	arg1	IL-6					1534:1537	pro-inflammatory factor IL-6	1510:1537	pro-inflammatory factor IL-6 in rats with periodontitis	1510:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	2	1	theme	ZIF-8	370:374	arg1	CHA-SH					376:381	ZIF-8@CHA-SH	370:381	ZIF-8@CHA-SH	370:381	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	1	2	theme	metal-organic	258:270	arg1	framework					272:280	metal-organic framework	258:280	metal-organic framework for the treatment of periodontitis in rats	258:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	11	3	dep	CONCLUSIONS	1567:1577	arg1	provids					1696:1702	provids	1696:1702	provids a new strategy for the treatment of periodontal diseases in the future	1696:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	11	3	dep	CONCLUSIONS	1567:1577	arg1	has					1592:1594	has	1592:1594	has excellent biological performance, which can effectively treat periodontitis caused by bacteria	1592:1689	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	6	4	theme	statistical	834:844	arg1	analysis					846:853	statistical analysis	834:853	statistical analysis	834:853	GraphPad Prism 7.0 software was used for statistical analysis.					
36710550	7	5	theme	@	897:897	arg1	CHA-SH					898:903	ZIF-8@CHA-SH	892:903	ZIF-8@CHA-SH	892:903	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	1	6	theme	adhesive	179:186	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	6	theme	adhesive	179:186	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	8	7	theme	@	1043:1043	arg1	CHA-SH					1044:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	1	8	from	treatment	290:298	arg1	rats					320:323	rats	320:323	rats	320:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	7	9	theme	successful	868:877	arg1	synthesis					879:887	The successful synthesis	864:887	The successful synthesis of ZIF-8@CHA-SH	864:903	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	1	10	theme	calcium	196:202	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	10	theme	calcium	196:202	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	5	11	theme	ZIF-8	743:747	arg1	CHA-SH					749:754	ZIF-8@CHA-SH	743:754	ZIF-8@CHA-SH	743:754	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	3	12	theme	scanning	529:536	arg1	microscope					547:556	scanning electron microscope	529:556	scanning electron microscope	529:556	The antibacterial properties were detected by plate coating method and scanning electron microscope.					
36710550	1	13	theme	composite	213:221	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	13	theme	composite	213:221	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	11	14	from	future	1768:1773	arg1	treatment					1727:1735	the treatment	1723:1735	the treatment of periodontal diseases in the future	1723:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	5	15	theme	CHA-SH	749:754	arg1	anti-inflammatory					686:702	anti-inflammatory	686:702	anti-inflammatory	686:702	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	11	16	from	treatment	1727:1735	arg1	future					1768:1773	future	1768:1773	future	1768:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	4	17	used	used	611:614	arg2	staining					597:604	live/dead cell fluorescence staining	569:604	live/dead cell fluorescence staining	569:604	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	4	17	used	used	611:614	arg2	CCK-8					559:563	CCK-8	559:563	CCK-8	559:563	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	5	18	theme	repair	715:720	arg1	effects					732:738	The anti-inflammatory and tissue repair promoting effects	682:738	effects	732:738	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	9	19	theme	viability	1274:1282	arg1	rate					1284:1287	The cell viability rate	1265:1287	The cell viability rate of ZIF-8@CHA-SH	1265:1303	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	19	theme	viability	1274:1282	arg1	%					1321:1321	(91.64±3.66)%	1309:1321	(91.64±3.66)%	1309:1321	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	2	20	dep	METHODS	326:332	arg1	characterization					350:365	characterization	350:365	characterization	350:365	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	2	20	dep	METHODS	326:332	arg1	Preparation					334:344	Preparation	334:344	Preparation	334:344	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	2	20	dep	METHODS	326:332	arg1	METHODS					326:332	METHODS Preparation and characterization	326:365	METHODS Preparation and characterization of ZIF-8@CHA-SH	326:381	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	8	21	contain	had	1051:1053	arg1	CHA-SH					1044:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	8	21	contain	had	1051:1053	arg2	ability					1079:1085	excellent antibacterial ability	1055:1085	excellent antibacterial ability	1055:1085	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	9	22	theme	@	1297:1297	arg1	CHA-SH					1298:1303	ZIF-8@CHA-SH	1292:1303	ZIF-8@CHA-SH	1292:1303	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	1	23	contain	containing	247:256	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	23	contain	containing	247:256	arg2	framework					272:280	metal-organic framework	258:280	metal-organic framework for the treatment of periodontitis in rats	258:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	23	contain	containing	247:256	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	7	24	theme	X-ray	1019:1023	arg1	diffraction					1025:1035	X-ray diffraction	1019:1035	X-ray diffraction	1019:1035	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	11	25	theme	periodontal	1740:1750	arg1	diseases					1752:1759	periodontal diseases	1740:1759	periodontal diseases in the future	1740:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	0	26	theme	zeolite	86:92	arg1	imidazole					94:102	zinc-based zeolite imidazole	75:102	zinc-based zeolite imidazole for the treatment of periodontitis	75:137	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	8	27	theme	antibacterial	1065:1077	arg1	ability					1079:1085	excellent antibacterial ability	1055:1085	excellent antibacterial ability	1055:1085	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	10	28	theme	ZIF-8	1423:1427	arg1	CHA-SH					1429:1434	ZIF-8@CHA-SH	1423:1434	ZIF-8@CHA-SH	1423:1434	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	29	with	rats	1542:1545	arg1	periodontitis					1552:1564	periodontitis	1552:1564	periodontitis	1552:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	7	30	dep	Fourier	975:981	arg1	transform					983:991	transform	983:991	transform infrared spectroscopy	983:1013	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	5	31	theme	animal	773:778	arg1	experiments					780:790	animal experiments	773:790	animal experiments	773:790	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	9	32	theme	co-culture	1339:1348	arg1	days					1331:1334	5 days	1329:1334	5 days of co-culture with human gingival fibroblasts (P=0.6)	1329:1388	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	7	33	theme	spectrum	956:963	arg1	analysis					965:972	energy spectrum analysis	949:972	energy spectrum analysis	949:972	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	4	34	theme	cell	579:582	arg1	staining					597:604	live/dead cell fluorescence staining	569:604	live/dead cell fluorescence staining	569:604	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	0	35	theme	sulfylated	16:25	arg1	hydrogel					54:61	sulfylated calcium alginate composite hydrogel	16:61	sulfylated calcium alginate composite hydrogel	16:61	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	10	36	from	IL-6	1534:1537	arg1	rats					1542:1545	rats	1542:1545	rats with periodontitis	1542:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	37	theme	inflammatory	1469:1480	arg1	cells					1482:1486	inflammatory cells	1469:1486	inflammatory cells	1469:1486	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	3	38	theme	antibacterial	462:474	arg1	properties					476:485	The antibacterial properties	458:485	The antibacterial properties	458:485	The antibacterial properties were detected by plate coating method and scanning electron microscope.					
36710550	0	39	theme	alginate	35:42	arg1	hydrogel					54:61	sulfylated calcium alginate composite hydrogel	16:61	sulfylated calcium alginate composite hydrogel	16:61	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	10	40	from	rats	1542:1545	arg1	expression					1496:1505	the expression	1492:1505	the expression of pro-inflammatory factor IL-6 in rats with periodontitis	1492:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	40	from	rats	1542:1545	arg1	infiltration					1453:1464	the infiltration	1449:1464	the infiltration of inflammatory cells	1449:1486	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	41	theme	pro-inflammatory	1510:1525	arg1	IL-6					1534:1537	pro-inflammatory factor IL-6	1510:1537	pro-inflammatory factor IL-6 in rats with periodontitis	1510:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	6	42	theme	GraphPad	793:800	arg1	software					812:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software was used for statistical analysis.					
36710550	3	43	theme	coating	510:516	arg1	method					518:523	plate coating method	504:523	plate coating method	504:523	The antibacterial properties were detected by plate coating method and scanning electron microscope.					
36710550	0	44	theme	hydrogel	54:61	arg1	[Application					0:11	[Application	0:11	[Application of sulfylated calcium alginate composite hydrogel	0:61	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	9	45	theme	gingival	1361:1368	arg1	P=0.6					1383:1387	P=0.6	1383:1387	P=0.6	1383:1387	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	45	theme	gingival	1361:1368	arg1	fibroblasts					1370:1380	human gingival fibroblasts	1355:1380	human gingival fibroblasts (P=0.6)	1355:1388	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	11	46	theme	@	1584:1584	arg1	CHA-SH					1585:1590	@CHA-SH	1584:1590	@CHA-SH	1584:1590	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	7	47	theme	energy	949:954	arg1	analysis					965:972	energy spectrum analysis	949:972	energy spectrum analysis	949:972	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	1	48	theme	ZIF-8	233:237	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	48	theme	ZIF-8	233:237	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	3	49	theme	electron	538:545	arg1	microscope					547:556	scanning electron microscope	529:556	scanning electron microscope	529:556	The antibacterial properties were detected by plate coating method and scanning electron microscope.					
36710550	11	50	contain	has	1592:1594	arg1	CHA-SH					1585:1590	@CHA-SH	1584:1590	@CHA-SH	1584:1590	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	11	50	contain	has	1592:1594	arg2	performance					1617:1627	excellent biological performance	1596:1627	excellent biological performance	1596:1627	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	4	51	theme	ZIF-8	644:648	arg1	CHA-SH					650:655	ZIF-8@CHA-SH	644:655	ZIF-8@CHA-SH	644:655	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	10	52	theme	IL-6	1534:1537	arg1	expression					1496:1505	the expression	1492:1505	the expression of pro-inflammatory factor IL-6 in rats with periodontitis	1492:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	52	theme	IL-6	1534:1537	arg1	infiltration					1453:1464	the infiltration	1449:1464	the infiltration of inflammatory cells	1449:1486	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	11	53	theme	biological	1606:1615	arg1	performance					1617:1627	excellent biological performance	1596:1627	excellent biological performance	1596:1627	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	2	54	theme	@	375:375	arg1	CHA-SH					376:381	ZIF-8@CHA-SH	370:381	ZIF-8@CHA-SH	370:381	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	7	55	theme	scanning	919:926	arg1	microscopy					937:946	scanning electron microscopy	919:946	scanning electron microscopy	919:946	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	8	56	theme	ZIF-8	1038:1042	arg1	CHA-SH					1044:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH	1038:1049	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	7	57	theme	CHA-SH	898:903	arg1	synthesis					879:887	The successful synthesis	864:887	The successful synthesis of ZIF-8@CHA-SH	864:903	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	4	58	from	toxicity	632:639	arg1	fibroblasts					669:679	gingival fibroblasts	660:679	gingival fibroblasts	660:679	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	9	59	with	co-culture	1339:1348	arg1	P=0.6					1383:1387	P=0.6	1383:1387	P=0.6	1383:1387	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	59	with	co-culture	1339:1348	arg1	fibroblasts					1370:1380	human gingival fibroblasts	1355:1380	human gingival fibroblasts (P=0.6)	1355:1388	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	7	60	theme	ZIF-8	892:896	arg1	CHA-SH					898:903	ZIF-8@CHA-SH	892:903	ZIF-8@CHA-SH	892:903	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	1	61	theme	thiomer	188:194	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	61	theme	thiomer	188:194	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	8	62	theme	excellent	1055:1063	arg1	ability					1079:1085	excellent antibacterial ability	1055:1085	excellent antibacterial ability	1055:1085	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	10	63	theme	In	1391:1392	arg1	experiments					1399:1409	In vivo experiments	1391:1409	In vivo experiments	1391:1409	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	1	64	theme	alginate	204:211	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	64	theme	alginate	204:211	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	4	65	theme	CHA-SH	650:655	arg1	toxicity					632:639	the toxicity	628:639	the toxicity of ZIF-8@CHA-SH on gingival fibroblasts	628:679	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	5	66	theme	@	748:748	arg1	CHA-SH					749:754	ZIF-8@CHA-SH	743:754	ZIF-8@CHA-SH	743:754	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	6	67	used	used	825:828	arg2	software					812:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software was used for statistical analysis.					
36710550	1	68	theme	hydrogel	223:230	arg1	feasibility					164:174	the feasibility	160:174	the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	160:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	4	69	theme	gingival	660:667	arg1	fibroblasts					669:679	gingival fibroblasts	660:679	gingival fibroblasts	660:679	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	5	70	theme	tissue	708:713	arg1	effects					732:738	The anti-inflammatory and tissue repair promoting effects	682:738	effects	732:738	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	9	71	theme	cell	1269:1272	arg1	rate					1284:1287	The cell viability rate	1265:1287	The cell viability rate of ZIF-8@CHA-SH	1265:1303	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	71	theme	cell	1269:1272	arg1	%					1321:1321	(91.64±3.66)%	1309:1321	(91.64±3.66)%	1309:1321	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	10	72	from	infiltration	1453:1464	arg1	rats					1542:1545	rats	1542:1545	rats with periodontitis	1542:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	7	73	dep	transform	983:991	arg1	infrared					993:1000	infrared	993:1000	transform infrared spectroscopy	983:1013	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	5	74	theme	promoting	722:730	arg1	effects					732:738	The anti-inflammatory and tissue repair promoting effects	682:738	effects	732:738	The anti-inflammatory and tissue repair promoting effects of ZIF-8@CHA-SH were verified by animal experiments.					
36710550	11	75	from	diseases	1752:1759	arg1	future					1768:1773	future	1768:1773	future	1768:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	11	76	theme	diseases	1752:1759	arg1	treatment					1727:1735	the treatment	1723:1735	the treatment of periodontal diseases in the future	1723:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	0	77	theme	zinc-based	75:84	arg1	imidazole					94:102	zinc-based zeolite imidazole	75:102	zinc-based zeolite imidazole for the treatment of periodontitis	75:137	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	9	78	theme	ZIF-8	1292:1296	arg1	CHA-SH					1298:1303	ZIF-8@CHA-SH	1292:1303	ZIF-8@CHA-SH	1292:1303	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	10	79	dep	In	1391:1392	arg1	vivo					1394:1397	vivo	1394:1397	vivo	1394:1397	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	9	80	theme	CHA-SH	1298:1303	arg1	rate					1284:1287	The cell viability rate	1265:1287	The cell viability rate of ZIF-8@CHA-SH	1265:1303	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	80	theme	CHA-SH	1298:1303	arg1	%					1321:1321	(91.64±3.66)%	1309:1321	(91.64±3.66)%	1309:1321	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	10	81	from	expression	1496:1505	arg1	rats					1542:1545	rats	1542:1545	rats with periodontitis	1542:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	0	82	theme	periodontitis	125:137	arg1	treatment					112:120	the treatment	108:120	the treatment of periodontitis	108:137	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	10	83	theme	@	1428:1428	arg1	CHA-SH					1429:1434	ZIF-8@CHA-SH	1423:1434	ZIF-8@CHA-SH	1423:1434	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	8	84	theme	antibacterial	1096:1108	arg1	rates					1110:1114	the antibacterial rates	1092:1114	the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans	1092:1187	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	8	84	theme	antibacterial	1096:1108	arg1	%					1206:1206	(99.88±0.12)%	1194:1206	(99.88±0.12)%	1194:1206	ZIF-8@CHA-SH had excellent antibacterial ability, and the antibacterial rates against Escherichia coli, Staphylococcus aureus and Streptococcus mutans were (99.88±0.12)%, (99.81±0.32)% and (95.53±3.08)%, respectively（P<0.001）.					
36710550	4	85	theme	fluorescence	584:595	arg1	staining					597:604	live/dead cell fluorescence staining	569:604	live/dead cell fluorescence staining	569:604	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	0	86	theme	calcium	27:33	arg1	hydrogel					54:61	sulfylated calcium alginate composite hydrogel	16:61	sulfylated calcium alginate composite hydrogel	16:61	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	10	87	theme	cells	1482:1486	arg1	expression					1496:1505	the expression	1492:1505	the expression of pro-inflammatory factor IL-6 in rats with periodontitis	1492:1564	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	10	87	theme	cells	1482:1486	arg1	infiltration					1453:1464	the infiltration	1449:1464	the infiltration of inflammatory cells	1449:1486	In vivo experiments showed that ZIF-8@CHA-SH could reduce the infiltration of inflammatory cells and the expression of pro-inflammatory factor IL-6 in rats with periodontitis.					
36710550	2	88	theme	chemical	422:429	arg1	composition					431:441	chemical composition	422:441	chemical composition	422:441	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	0	89	theme	composite	44:52	arg1	hydrogel					54:61	sulfylated calcium alginate composite hydrogel	16:61	sulfylated calcium alginate composite hydrogel	16:61	[Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis].					
36710550	1	90	theme	periodontitis	303:315	arg1	treatment					290:298	the treatment	286:298	the treatment of periodontitis in rats	286:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	6	91	theme	Prism	802:806	arg1	software					812:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software	793:819	GraphPad Prism 7.0 software was used for statistical analysis.					
36710550	9	92	theme	human	1355:1359	arg1	P=0.6					1383:1387	P=0.6	1383:1387	P=0.6	1383:1387	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	9	92	theme	human	1355:1359	arg1	fibroblasts					1370:1380	human gingival fibroblasts	1355:1380	human gingival fibroblasts (P=0.6)	1355:1388	The cell viability rate of ZIF-8@CHA-SH was (91.64±3.66)% after 5 days of co-culture with human gingival fibroblasts (P=0.6).					
36710550	4	93	theme	live/dead	569:577	arg1	staining					597:604	live/dead cell fluorescence staining	569:604	live/dead cell fluorescence staining	569:604	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	11	94	theme	new	1706:1708	arg1	strategy					1710:1717	a new strategy	1704:1717	a new strategy for the treatment of periodontal diseases in the future	1704:1773	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	7	95	dep	RESULTS	856:862	arg1	proved					909:914	proved	909:914	was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction	905:1035	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	3	96	theme	plate	504:508	arg1	method					518:523	plate coating method	504:523	plate coating method	504:523	The antibacterial properties were detected by plate coating method and scanning electron microscope.					
36710550	7	97	theme	electron	928:935	arg1	microscopy					937:946	scanning electron microscopy	919:946	scanning electron microscopy	919:946	RESULTS The successful synthesis of ZIF-8@CHA-SH was proved by scanning electron microscopy, energy spectrum analysis, Fourier transform infrared spectroscopy and X-ray diffraction.					
36710550	1	98	theme	@	238:238	arg1	CHA-SH					239:244	ZIF-8@CHA-SH	233:244	ZIF-8@CHA-SH	233:244	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	1	98	theme	@	238:238	arg1	hydrogel					223:230	adhesive thiomer calcium alginate composite hydrogel	179:230	adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats	179:323	PURPOSE To explore the feasibility of adhesive thiomer calcium alginate composite hydrogel (ZIF-8@CHA-SH) containing metal-organic framework for the treatment of periodontitis in rats.					
36710550	4	99	theme	@	649:649	arg1	CHA-SH					650:655	ZIF-8@CHA-SH	644:655	ZIF-8@CHA-SH	644:655	CCK-8 and live/dead cell fluorescence staining were used to evaluate the toxicity of ZIF-8@CHA-SH on gingival fibroblasts.					
36710550	11	100	theme	excellent	1596:1604	arg1	performance					1617:1627	excellent biological performance	1596:1627	excellent biological performance	1596:1627	CONCLUSIONS ZIF-8@CHA-SH has excellent biological performance, which can effectively treat periodontitis caused by bacteria, and provids a new strategy for the treatment of periodontal diseases in the future.					
36710550	2	101	theme	CHA-SH	376:381	arg1	characterization					350:365	characterization	350:365	characterization	350:365	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	2	101	theme	CHA-SH	376:381	arg1	Preparation					334:344	Preparation	334:344	Preparation	334:344	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36710550	2	101	theme	CHA-SH	376:381	arg1	METHODS					326:332	METHODS Preparation and characterization	326:365	METHODS Preparation and characterization of ZIF-8@CHA-SH	326:381	METHODS Preparation and characterization of ZIF-8@CHA-SH were performed, and the morphology and chemical composition were observed.					
36075168	8	0	theme	DPPH	807:810	arg1	capacity					831:838	DPPH radical scavenging capacity	807:838	DPPH radical scavenging capacity	807:838	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	2	1	theme	melt	338:341	arg1	blending					343:350	melt blending	338:350	melt blending	338:350	Both fractions were incorporated into corn starch to obtain films by melt blending and compression moulding.					
36075168	4	2	theme	film	499:502	arg1	stretchability					504:517	film stretchability	499:517	film stretchability	499:517	greatly increased the elastic modulus (by 200 %) and tensile strength at break (by 100 %) while reducing film stretchability.					
36075168	5	3	theme	water	577:581	arg1	vapour					583:588	water vapour	577:588	water vapour	577:588	Films with CF exhibited the greatest barrier capacity to water vapour and oxygen.					
36075168	9	4	theme	UV	1005:1006	arg1	radiation					1008:1016	UV radiation	1005:1016	UV radiation throughout 50 days	1005:1035	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	7	5	theme	certain	732:738	arg1	extent					740:745	a certain extent	730:745	a certain extent	730:745	plasticised the film's amorphous phase, but also reinforced the matrix to a certain extent.					
36075168	4	6	theme	tensile	447:453	arg1	strength					455:462	tensile strength	447:462	tensile strength	447:462	greatly increased the elastic modulus (by 200 %) and tensile strength at break (by 100 %) while reducing film stretchability.					
36075168	8	7	theme	scavenging	820:829	arg1	capacity					831:838	DPPH radical scavenging capacity	807:838	DPPH radical scavenging capacity	807:838	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	1	8	theme	Antioxidant	87:97	arg1	RS					119:120	RS	119:120	RS	119:120	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	1	8	theme	Antioxidant	87:97	arg1	straw					112:116	Antioxidant aqueous rice straw	87:116	Antioxidant aqueous rice straw (RS) extract	87:129	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	9	9	with	films	889:893	arg1	CF					900:901	CF	900:901	CF	900:901	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	9	9	with	films	889:893	arg1	extracts					910:917	RS extracts	907:917	RS extracts	907:917	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	8	10	theme	high	774:777	arg1	degree					779:784	a high degree	772:784	a high degree of UV absorption	772:801	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	6	11	from	6	641:641	arg1	incorporation					606:618	The incorporation	602:618	The incorporation of RS extract (at 4, 6 and 8 % wt.)	602:654	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	1	12	theme	extraction	249:258	arg1	residue					260:266	the extraction residue	245:266	the extraction residue	245:266	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	6	13	theme	extract	626:632	arg1	incorporation					606:618	The incorporation	602:618	The incorporation of RS extract (at 4, 6 and 8 % wt.)	602:654	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	1	14	theme	combined	149:156	arg1	process					184:190	a combined ultrasound-reflux heating process	147:190	a combined ultrasound-reflux heating process	147:190	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	0	15	theme	straw	51:55	arg1	extract					57:63	rice straw extract	46:63	rice straw extract	46:63	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	0	16	theme	rice	46:49	arg1	extract					57:63	rice straw extract	46:63	rice straw extract	46:63	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	6	17	theme	RS	623:624	arg1	extract					626:632	RS extract	623:632	RS extract	623:632	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	1	18	theme	ultrasound-reflux	158:174	arg1	process					184:190	a combined ultrasound-reflux heating process	147:190	a combined ultrasound-reflux heating process	147:190	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	0	19	theme	starch	12:17	arg1	films					29:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	5	20	theme	barrier	557:563	arg1	capacity					565:572	the greatest barrier capacity	544:572	the greatest barrier capacity	544:572	Films with CF exhibited the greatest barrier capacity to water vapour and oxygen.					
36075168	2	21	theme	corn	307:310	arg1	starch					312:317	corn starch	307:317	corn starch	307:317	Both fractions were incorporated into corn starch to obtain films by melt blending and compression moulding.					
36075168	1	22	theme	heating	176:182	arg1	process					184:190	a combined ultrasound-reflux heating process	147:190	a combined ultrasound-reflux heating process	147:190	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	0	23	theme	Antioxidant	0:10	arg1	films					29:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	7	24	theme	amorphous	679:687	arg1	phase					689:693	the film's amorphous phase	668:693	the film's amorphous phase	668:693	plasticised the film's amorphous phase, but also reinforced the matrix to a certain extent.					
36075168	1	25	theme	aqueous	99:105	arg1	RS					119:120	RS	119:120	RS	119:120	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	1	25	theme	aqueous	99:105	arg1	straw					112:116	Antioxidant aqueous rice straw	87:116	Antioxidant aqueous rice straw (RS) extract	87:129	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	9	26	theme	great	930:934	arg1	extent					936:941	a great extent	928:941	a great extent	928:941	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	2	27	theme	compression	356:366	arg1	moulding					368:375	compression moulding	356:375	compression moulding	356:375	Both fractions were incorporated into corn starch to obtain films by melt blending and compression moulding.					
36075168	9	28	theme	accelerated	972:982	arg1	test					994:997	an accelerated oxidative test	969:997	an accelerated oxidative test under UV radiation throughout 50 days	969:1035	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	1	29	theme	rice	107:110	arg1	RS					119:120	RS	119:120	RS	119:120	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	1	29	theme	rice	107:110	arg1	straw					112:116	Antioxidant aqueous rice straw	87:116	Antioxidant aqueous rice straw (RS) extract	87:129	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	8	30	theme	active	752:757	arg1	films					759:763	The active films	748:763	The active films	748:763	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	0	31	theme	composite	19:27	arg1	films					29:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films	0:33	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	8	32	theme	UV	789:790	arg1	absorption					792:801	UV absorption	789:801	UV absorption	789:801	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	1	33	theme	straw	112:116	arg1	extract					123:129	Antioxidant aqueous rice straw (RS) extract	87:129	Antioxidant aqueous rice straw (RS) extract	87:129	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	9	34	theme	sunflower	851:859	arg1	bags					865:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	1	35	theme	cellulose	196:204	arg1	CF					214:215	CF	214:215	CF	214:215	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	1	35	theme	cellulose	196:204	arg1	fibres					206:211	cellulose fibres	196:211	cellulose fibres (CF)	196:216	Antioxidant aqueous rice straw (RS) extract was obtained by a combined ultrasound-reflux heating process and cellulose fibres (CF) were purified by bleaching the extraction residue.					
36075168	3	36	theme	3 	385:386	arg1	wt					389:390	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	3	36	theme	3 	385:386	arg1	CF					378:379	CF	378:379	CF (at 3 % wt.)	378:392	CF (at 3 % wt.)					
36075168	9	37	theme	RS	907:908	arg1	extracts					910:917	RS extracts	907:917	RS extracts	907:917	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	3	38	theme	%	387:387	arg1	wt					389:390	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	3	38	theme	%	387:387	arg1	CF					378:379	CF	378:379	CF (at 3 % wt.)	378:392	CF (at 3 % wt.)					
36075168	9	39	theme	oil	861:863	arg1	bags					865:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	9	40	theme	oil	952:954	arg1	oxidation					956:964	oil oxidation	952:964	oil oxidation	952:964	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	9	41	theme	oxidative	984:992	arg1	test					994:997	an accelerated oxidative test	969:997	an accelerated oxidative test under UV radiation throughout 50 days	969:1035	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	4	42	theme	elastic	416:422	arg1	modulus					424:430	the elastic modulus	412:430	the elastic modulus (by 200 %)	412:441	greatly increased the elastic modulus (by 200 %) and tensile strength at break (by 100 %) while reducing film stretchability.					
36075168	6	43	theme	%	649:649	arg1	wt					651:652	8 % wt	647:652	8 % wt	647:652	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	3	44	theme	at	382:383	arg1	wt					389:390	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	3	44	theme	at	382:383	arg1	CF					378:379	CF	378:379	CF (at 3 % wt.)	378:392	CF (at 3 % wt.)					
36075168	5	45	with	Films	520:524	arg1	CF					531:532	CF	531:532	CF	531:532	Films with CF exhibited the greatest barrier capacity to water vapour and oxygen.					
36075168	5	46	theme	greatest	548:555	arg1	capacity					565:572	the greatest barrier capacity	544:572	the greatest barrier capacity	544:572	Films with CF exhibited the greatest barrier capacity to water vapour and oxygen.					
36075168	6	47	theme	8 	647:648	arg1	wt					651:652	8 % wt	647:652	8 % wt	647:652	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	6	48	from	wt	651:652	arg1	incorporation					606:618	The incorporation	602:618	The incorporation of RS extract (at 4, 6 and 8 % wt.)	602:654	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	3	49	from	wt	389:390	arg1	at					382:383	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	3	49	from	wt	389:390	arg1	3 					385:386	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	3	49	from	wt	389:390	arg1	%					387:387	at 3 % wt.	382:391	at 3 % wt.	382:391	CF (at 3 % wt.)					
36075168	0	50	theme	cellulose	69:77	arg1	fibres					79:84	cellulose fibres	69:84	cellulose fibres	69:84	Antioxidant starch composite films containing rice straw extract and cellulose fibres.					
36075168	8	51	theme	absorption	792:801	arg1	degree					779:784	a high degree	772:784	a high degree of UV absorption	772:801	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	8	51	theme	absorption	792:801	arg1	capacity					831:838	DPPH radical scavenging capacity	807:838	DPPH radical scavenging capacity	807:838	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36075168	6	52	from	4	638:638	arg1	incorporation					606:618	The incorporation	602:618	The incorporation of RS extract (at 4, 6 and 8 % wt.)	602:654	The incorporation of RS extract (at 4, 6 and 8 % wt.)					
36075168	9	53	theme	Mono-dose	841:849	arg1	bags					865:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags	841:868	Mono-dose sunflower oil bags were obtained with films with CF and RS extracts that, to a great extent, prevent oil oxidation in an accelerated oxidative test under UV radiation throughout 50 days.					
36075168	8	54	theme	radical	812:818	arg1	capacity					831:838	DPPH radical scavenging capacity	807:838	DPPH radical scavenging capacity	807:838	The active films showed a high degree of UV absorption and DPPH radical scavenging capacity.					
36493483	0	0	theme	postharvest	108:118	arg1	storage					120:126	postharvest storage	108:126	postharvest storage in litchi fruit	108:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	3	1	theme	reactive	739:746	arg1	species					755:761	reactive oxygen species	739:761	the reactive oxygen species level of the treated Aspergillus niger cells	735:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	5	2	theme	application	1146:1156	arg1	safety					1132:1137	the qualified safety	1118:1137	the qualified safety of the application of the 0.6 % FT-AgNPs/CP	1118:1181	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	1	3	theme	vernicifluum	174:185	arg1	nanoparticles					211:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles	160:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities	160:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	3	theme	vernicifluum	174:185	arg1	FT-AgNPs					226:233	FT-AgNPs	226:233	FT-AgNPs	226:233	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	4	4	theme	control	1047:1053	arg1	d					1038:1038	9 d	1036:1038	9 d of the control	1036:1053	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	5	5	theme	0.024 μg/kg	1070:1080	arg1	Ag+					1082:1084	0.024 μg/kg Ag+ residual	1070:1093	0.024 μg/kg Ag+ residual in lichi pulp	1070:1107	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	1	6	theme	fisetin	187:193	arg1	nanoparticles					211:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles	160:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities	160:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	6	theme	fisetin	187:193	arg1	FT-AgNPs					226:233	FT-AgNPs	226:233	FT-AgNPs	226:233	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	2	7	theme	1:1	394:396	arg1	chitosan/pullulan					398:414	1:1 chitosan/pullulan	394:414	the 1:1 chitosan/pullulan (CS/PUL, CP) matrix	390:434	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	2	7	theme	1:1	394:396	arg1	CS/PUL					417:422	CS/PUL	417:422	CS/PUL	417:422	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	4	8	from	25 °C	986:990	arg1	storage					975:981	the storage	971:981	the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control)	971:1054	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	0	9	theme	storage	120:126	arg1	composite-film					70:83	reinforced chitosan/pullulan composite-film	41:83	reinforced chitosan/pullulan composite-film	41:83	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	0	9	theme	storage	120:126	arg1	application					93:103	its application	89:103	its application of postharvest storage in litchi fruit	89:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	5	10	theme	residual	1086:1093	arg1	Ag+					1082:1084	0.024 μg/kg Ag+ residual	1070:1093	0.024 μg/kg Ag+ residual in lichi pulp	1070:1107	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	3	11	theme	tensile	583:589	arg1	strength					591:598	the tensile strength	579:598	the tensile strength to 61.2 MPa	579:610	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	2	12	theme	chitosan/pullulan	398:414	arg1	matrix					429:434	the 1:1 chitosan/pullulan (CS/PUL, CP) matrix	390:434	the 1:1 chitosan/pullulan (CS/PUL, CP) matrix	390:434	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	0	13	from	composite-film	70:83	arg1	fruit					138:142	litchi fruit	131:142	litchi fruit	131:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	2	14	dep	CS/PUL	417:422	arg1	CP					425:426	CP	425:426	CP	425:426	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	1	15	theme	chelated	195:202	arg1	nanoparticles					211:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles	160:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities	160:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	15	theme	chelated	195:202	arg1	FT-AgNPs					226:233	FT-AgNPs	226:233	FT-AgNPs	226:233	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	0	16	theme	litchi	131:136	arg1	fruit					138:142	litchi fruit	131:142	litchi fruit	131:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	3	17	theme	oxygen	748:753	arg1	species					755:761	reactive oxygen species	739:761	the reactive oxygen species level of the treated Aspergillus niger cells	735:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	18	theme	hydrogen	441:448	arg1	bonding					450:456	The hydrogen bonding	437:456	The hydrogen bonding	437:456	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	4	19	theme	litchi	921:926	arg1	fruit					928:932	litchi fruit	921:932	litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control)	921:1054	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	1	20	theme	silver	204:209	arg1	nanoparticles					211:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles	160:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities	160:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	20	theme	silver	204:209	arg1	FT-AgNPs					226:233	FT-AgNPs	226:233	FT-AgNPs	226:233	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	3	21	theme	species	755:761	arg1	level					763:767	the reactive oxygen species level	735:767	the reactive oxygen species level of the treated Aspergillus niger cells	735:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	0	22	theme	Developing	0:9	arg1	fisetin-AgNPs					11:23	Developing fisetin-AgNPs	0:23	Developing fisetin-AgNPs	0:23	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	3	23	theme	Aspergillus	784:794	arg1	cells					802:806	the treated Aspergillus niger cells	772:806	the treated Aspergillus niger cells	772:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	24	theme	electrostatic	462:474	arg1	interaction					476:486	electrostatic interaction	462:486	electrostatic interaction between FT-AgNPs and CP	462:510	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	25	theme	niger	796:800	arg1	cells					802:806	the treated Aspergillus niger cells	772:806	the treated Aspergillus niger cells	772:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	2	26	theme	%	349:349	arg1	FT-AgNPs					351:358	0.6 wt% FT-AgNPs	343:358	0.6 wt% FT-AgNPs	343:358	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	5	27	theme	%	1169:1169	arg1	FT-AgNPs/CP					1171:1181	the 0.6 % FT-AgNPs/CP	1161:1181	the 0.6 % FT-AgNPs/CP	1161:1181	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	2	28	theme	0.6 wt	343:348	arg1	FT-AgNPs					351:358	0.6 wt% FT-AgNPs	343:358	0.6 wt% FT-AgNPs	343:358	To surprise, 0.6 wt% FT-AgNPs was compatibly dispersed into the 1:1 chitosan/pullulan (CS/PUL, CP) matrix.					
36493483	0	29	theme	chitosan/pullulan	52:68	arg1	composite-film					70:83	reinforced chitosan/pullulan composite-film	41:83	reinforced chitosan/pullulan composite-film	41:83	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	3	30	theme	treated	776:782	arg1	cells					802:806	the treated Aspergillus niger cells	772:806	the treated Aspergillus niger cells	772:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	4	31	dep	25 °C	986:990	arg1	d					1038:1038	9 d	1036:1038	9 d of the control	1036:1053	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	4	31	dep	25 °C	986:990	arg1	d					996:996	15 d	993:996	15 d of the 0.6 % FT-AgNPs/CP treatment	993:1031	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	3	32	theme	composite	692:700	arg1	film					715:718	the composite hydrocolloid film	688:718	the composite hydrocolloid film (FT-AgNPs/CP)	688:732	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	32	theme	composite	692:700	arg1	FT-AgNPs/CP					721:731	FT-AgNPs/CP	721:731	FT-AgNPs/CP	721:731	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	0	33	theme	reinforced	41:50	arg1	composite-film					70:83	reinforced chitosan/pullulan composite-film	41:83	reinforced chitosan/pullulan composite-film	41:83	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	4	34	theme	%	1009:1009	arg1	treatment					1023:1031	the 0.6 % FT-AgNPs/CP treatment	1001:1031	the 0.6 % FT-AgNPs/CP treatment	1001:1031	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	0	35	from	application	93:103	arg1	fruit					138:142	litchi fruit	131:142	litchi fruit	131:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	5	36	theme	FT-AgNPs/CP	1171:1181	arg1	application					1146:1156	the application	1142:1156	the application of the 0.6 % FT-AgNPs/CP	1142:1181	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	1	37	theme	outstanding	241:251	arg1	antioxidant					253:263	outstanding antioxidant	241:263	outstanding antioxidant	241:263	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	3	38	theme	thermal	539:545	arg1	stability					547:555	the CP thermal stability	532:555	the CP thermal stability	532:555	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	1	39	with	nanoparticles	211:223	arg1	antioxidant					253:263	outstanding antioxidant	241:263	outstanding antioxidant	241:263	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	39	with	nanoparticles	211:223	arg1	activities					283:292	antimicrobial activities	269:292	antimicrobial activities	269:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	5	40	theme	0.6 	1165:1168	arg1	%					1169:1169	%	1169:1169	%	1169:1169	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	3	41	theme	water	613:617	arg1	permeability					625:636	water vapor permeability	613:636	water vapor permeability below 20 kg/m2•d.	613:654	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	5	42	theme	lichi	1098:1102	arg1	pulp					1104:1107	lichi pulp	1098:1107	lichi pulp	1098:1107	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	5	43	theme	qualified	1122:1130	arg1	safety					1132:1137	the qualified safety	1118:1137	the qualified safety of the application of the 0.6 % FT-AgNPs/CP	1118:1181	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36493483	4	44	theme	treatment	1023:1031	arg1	d					996:996	15 d	993:996	15 d of the 0.6 % FT-AgNPs/CP treatment	993:1031	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	3	45	theme	cells	802:806	arg1	level					763:767	the reactive oxygen species level	735:767	the reactive oxygen species level of the treated Aspergillus niger cells	735:806	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	4	46	theme	fruit	928:932	arg1	decay					912:916	the decay	908:916	the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control)	908:1054	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	0	47	from	fruit	138:142	arg1	composite-film					70:83	reinforced chitosan/pullulan composite-film	41:83	reinforced chitosan/pullulan composite-film	41:83	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	0	47	from	fruit	138:142	arg1	application					93:103	its application	89:103	its application of postharvest storage in litchi fruit	89:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	3	48	theme	vapor	619:623	arg1	permeability					625:636	water vapor permeability	613:636	water vapor permeability below 20 kg/m2•d.	613:654	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	49	theme	CP	536:537	arg1	stability					547:555	the CP thermal stability	532:555	the CP thermal stability	532:555	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	4	50	theme	microbial	945:953	arg1	infection					955:963	microbial infection	945:963	microbial infection	945:963	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	4	51	theme	FT-AgNPs/CP	1011:1021	arg1	treatment					1023:1031	the 0.6 % FT-AgNPs/CP treatment	1001:1031	the 0.6 % FT-AgNPs/CP treatment	1001:1031	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	3	52	theme	hydrocolloid	702:713	arg1	film					715:718	the composite hydrocolloid film	688:718	the composite hydrocolloid film (FT-AgNPs/CP)	688:732	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	52	theme	hydrocolloid	702:713	arg1	FT-AgNPs/CP					721:731	FT-AgNPs/CP	721:731	FT-AgNPs/CP	721:731	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	3	53	theme	membrane	845:852	arg1	permeability					854:865	the membrane permeability	841:865	the membrane permeability	841:865	The hydrogen bonding and electrostatic interaction between FT-AgNPs and CP, slightly increased the CP thermal stability, and greatly enhanced the tensile strength to 61.2 MPa, water vapor permeability below 20 kg/m2•d. Furthermore, after treated with the composite hydrocolloid film (FT-AgNPs/CP), the reactive oxygen species level of the treated Aspergillus niger cells was significantly increased, and the membrane permeability was enhanced.					
36493483	0	54	from	storage	120:126	arg1	fruit					138:142	litchi fruit	131:142	litchi fruit	131:142	Developing fisetin-AgNPs incorporated in reinforced chitosan/pullulan composite-film and its application of postharvest storage in litchi fruit.					
36493483	1	55	theme	antimicrobial	269:281	arg1	activities					283:292	antimicrobial activities	269:292	antimicrobial activities	269:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	4	56	theme	0.6 	1005:1008	arg1	%					1009:1009	%	1009:1009	%	1009:1009	It effectively slowed down the decay of litchi fruit induced by microbial infection under the storage at 25 °C (15 d of the 0.6 % FT-AgNPs/CP treatment vs 9 d of the control).					
36493483	1	57	theme	Toxicodendron	160:172	arg1	nanoparticles					211:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles	160:223	Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities	160:292	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	1	57	theme	Toxicodendron	160:172	arg1	FT-AgNPs					226:233	FT-AgNPs	226:233	FT-AgNPs	226:233	In this study, Toxicodendron vernicifluum fisetin chelated silver nanoparticles (FT-AgNPs) with outstanding antioxidant and antimicrobial activities were constructed via self-assembly.					
36493483	5	58	from	Ag+	1082:1084	arg1	pulp					1104:1107	lichi pulp	1098:1107	lichi pulp	1098:1107	In addition, 0.024 μg/kg Ag+ residual in lichi pulp verified the qualified safety of the application of the 0.6 % FT-AgNPs/CP.					
36596190	0	0	theme	edible	71:76	arg1	asparagus					33:41	green asparagus	27:41	green asparagus (Asparagus officinalis L.)	27:68	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	0	theme	edible	71:76	arg1	part					78:81	edible part	71:81	edible part	71:81	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	4	1	theme	non-edible	654:663	arg1	parts					665:669	the non-edible parts	650:669	the non-edible parts	650:669	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36596190	0	2	theme	human	148:152	arg1	bacteria					169:176	human gut-associated bacteria	148:176	human gut-associated bacteria	148:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	2	3	theme	non-digestible	316:329	arg1	carbohydrates					331:343	non-digestible carbohydrates	316:343	non-digestible carbohydrates	316:343	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	7	4	theme	asparagus	977:985	arg1	part					965:968	any part	961:968	any part of the asparagus	961:985	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	0	5	from	growth	138:143	arg1	composition					12:22	Nutritional composition	0:22	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products,	0:98	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	5	from	growth	138:143	arg1	assessment					104:113	assessment	104:113	assessment of their effect on the growth of human gut-associated bacteria	104:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	6	6	used	used	840:843	arg2	by-product					810:819	the spear by-product	800:819	the spear by-product	800:819	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	0	7	from	composition	12:22	arg1	growth					138:143	the growth	134:143	the growth of human gut-associated bacteria	134:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	3	8	theme	gut-associated	471:484	arg1	bacteria					486:493	human gut-associated bacteria	465:493	human gut-associated bacteria	465:493	Their activity on the growth of human gut-associated bacteria has been studied.					
36596190	1	9	theme	high	225:228	arg1	content					230:236	a high content	223:236	a high content of bioactive compounds	223:259	Asparagus is considered a healthy food with a high content of bioactive compounds.					
36596190	0	10	theme	bacteria	169:176	arg1	growth					138:143	the growth	134:143	the growth of human gut-associated bacteria	134:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	7	11	theme	able	1120:1123	arg1	compounds					1110:1118	the compounds	1106:1118	the compounds able to modulate the human gut microbiota	1106:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	0	12	theme	gut-associated	154:167	arg1	bacteria					169:176	human gut-associated bacteria	148:176	human gut-associated bacteria	148:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	3	13	theme	human	465:469	arg1	bacteria					486:493	human gut-associated bacteria	465:493	human gut-associated bacteria	465:493	Their activity on the growth of human gut-associated bacteria has been studied.					
36596190	0	14	from	effect	124:129	arg1	growth					138:143	the growth	134:143	the growth of human gut-associated bacteria	134:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	5	15	theme	remarkable	699:708	arg1	content					710:716	A remarkable content	697:716	A remarkable content in xylose, inulin, flavonoids and saponins	697:759	A remarkable content in xylose, inulin, flavonoids and saponins has been found.					
36596190	2	16	theme	edible	372:377	arg1	spear					379:383	edible spear	372:383	edible spear	372:383	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	4	17	theme	functional	558:567	arg1	value					569:573	the high nutritional and functional value	533:573	the high nutritional and functional value of the asparagus, including its by-products	533:617	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36596190	7	18	contain	has	987:989	arg2	potential					993:1001	a potential future	991:1008	a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota	991:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	7	18	contain	has	987:989	arg1	part					965:968	any part	961:968	any part of the asparagus	961:985	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	7	19	theme	human	1141:1145	arg1	microbiota					1151:1160	the human gut microbiota	1137:1160	the human gut microbiota	1137:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	6	20	theme	strains	925:931	arg1	growth					860:865	the growth	856:865	the growth of commensal or probiotic lactobacilli and bifidobacteria strains	856:931	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	0	21	theme	Nutritional	0:10	arg1	composition					12:22	Nutritional composition	0:22	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products,	0:98	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	1	22	theme	bioactive	241:249	arg1	compounds					251:259	bioactive compounds	241:259	bioactive compounds	241:259	Asparagus is considered a healthy food with a high content of bioactive compounds.					
36596190	7	23	theme	healthy	1015:1021	arg1	food					1023:1026	a healthy food	1013:1026	a healthy food	1013:1026	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	2	24	theme	bioactive	349:357	arg1	compounds					359:367	bioactive compounds	349:367	bioactive compounds	349:367	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	0	25	theme	green	27:31	arg1	L.					66:67	Asparagus officinalis L.	44:67	Asparagus officinalis L.	44:67	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	25	theme	green	27:31	arg1	by-products					87:97	by-products	87:97	by-products	87:97	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	25	theme	green	27:31	arg1	part					78:81	edible part	71:81	edible part	71:81	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	25	theme	green	27:31	arg1	asparagus					33:41	green asparagus	27:41	green asparagus (Asparagus officinalis L.)	27:68	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	1	26	theme	compounds	251:259	arg1	content					230:236	a high content	223:236	a high content of bioactive compounds	223:259	Asparagus is considered a healthy food with a high content of bioactive compounds.					
36596190	7	27	theme	future	1003:1008	arg1	potential					993:1001	a potential future	991:1008	a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota	991:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	2	28	theme	by-product	392:401	arg1	composition					303:313	the proximate and mineral composition	277:313	the proximate and mineral composition	277:313	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	28	theme	by-product	392:401	arg1	carbohydrates					331:343	non-digestible carbohydrates	316:343	non-digestible carbohydrates	316:343	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	28	theme	by-product	392:401	arg1	compounds					359:367	bioactive compounds	349:367	bioactive compounds	349:367	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	7	29	dep	ingredients	1051:1061	arg1	required					1085:1092	required	1085:1092	is required to identify the compounds able to modulate the human gut microbiota	1082:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	4	30	theme	high	537:540	arg1	value					569:573	the high nutritional and functional value	533:573	the high nutritional and functional value of the asparagus, including its by-products	533:617	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36596190	4	31	theme	parts	665:669	arg1	potential					637:645	the potential	633:645	the potential of the non-edible parts to be used as prebiotics	633:694	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36596190	2	32	theme	spear	386:390	arg1	by-product					392:401	spear by-product	386:401	spear by-product	386:401	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	6	33	theme	lactobacilli	893:904	arg1	strains					925:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	5	34	from	content	710:716	arg1	xylose					721:726	xylose	721:726	xylose	721:726	A remarkable content in xylose, inulin, flavonoids and saponins has been found.					
36596190	5	34	from	content	710:716	arg1	saponins					752:759	saponins	752:759	saponins	752:759	A remarkable content in xylose, inulin, flavonoids and saponins has been found.					
36596190	5	34	from	content	710:716	arg1	flavonoids					737:746	flavonoids	737:746	flavonoids	737:746	A remarkable content in xylose, inulin, flavonoids and saponins has been found.					
36596190	5	34	from	content	710:716	arg1	inulin					729:734	inulin	729:734	inulin	729:734	A remarkable content in xylose, inulin, flavonoids and saponins has been found.					
36596190	0	35	theme	asparagus	33:41	arg1	composition					12:22	Nutritional composition	0:22	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products,	0:98	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	35	theme	asparagus	33:41	arg1	assessment					104:113	assessment	104:113	assessment of their effect on the growth of human gut-associated bacteria	104:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	6	36	theme	probiotic	883:891	arg1	strains					925:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	4	37	theme	nutritional	542:552	arg1	value					569:573	the high nutritional and functional value	533:573	the high nutritional and functional value of the asparagus, including its by-products	533:617	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36596190	2	38	theme	root	407:410	arg1	composition					303:313	the proximate and mineral composition	277:313	the proximate and mineral composition	277:313	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	38	theme	root	407:410	arg1	carbohydrates					331:343	non-digestible carbohydrates	316:343	non-digestible carbohydrates	316:343	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	38	theme	root	407:410	arg1	compounds					359:367	bioactive compounds	349:367	bioactive compounds	349:367	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	39	theme	spear	379:383	arg1	composition					303:313	the proximate and mineral composition	277:313	the proximate and mineral composition	277:313	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	39	theme	spear	379:383	arg1	carbohydrates					331:343	non-digestible carbohydrates	316:343	non-digestible carbohydrates	316:343	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	2	39	theme	spear	379:383	arg1	compounds					359:367	bioactive compounds	349:367	bioactive compounds	349:367	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	0	40	theme	officinalis	54:64	arg1	L.					66:67	Asparagus officinalis L.	44:67	Asparagus officinalis L.	44:67	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	40	theme	officinalis	54:64	arg1	asparagus					33:41	green asparagus	27:41	green asparagus (Asparagus officinalis L.)	27:68	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	7	41	theme	gut	1147:1149	arg1	microbiota					1151:1160	the human gut microbiota	1137:1160	the human gut microbiota	1137:1160	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	6	42	theme	bifidobacteria	910:923	arg1	strains					925:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	0	43	theme	Asparagus	44:52	arg1	L.					66:67	Asparagus officinalis L.	44:67	Asparagus officinalis L.	44:67	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	43	theme	Asparagus	44:52	arg1	asparagus					33:41	green asparagus	27:41	green asparagus (Asparagus officinalis L.)	27:68	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	6	44	theme	commensal	870:878	arg1	strains					925:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	commensal or probiotic lactobacilli and bifidobacteria strains	870:931	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	0	45	theme	effect	124:129	arg1	composition					12:22	Nutritional composition	0:22	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products,	0:98	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	0	45	theme	effect	124:129	arg1	assessment					104:113	assessment	104:113	assessment of their effect on the growth of human gut-associated bacteria	104:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	2	46	theme	mineral	295:301	arg1	composition					303:313	the proximate and mineral composition	277:313	the proximate and mineral composition	277:313	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	3	47	from	activity	439:446	arg1	growth					455:460	the growth	451:460	the growth of human gut-associated bacteria	451:493	Their activity on the growth of human gut-associated bacteria has been studied.					
36596190	1	48	with	food	213:216	arg1	content					230:236	a high content	223:236	a high content of bioactive compounds	223:259	Asparagus is considered a healthy food with a high content of bioactive compounds.					
36596190	2	49	theme	proximate	281:289	arg1	composition					303:313	the proximate and mineral composition	277:313	the proximate and mineral composition	277:313	In this study, the proximate and mineral composition, non-digestible carbohydrates and bioactive compounds of edible spear, spear by-product and root have been evaluated.					
36596190	1	50	theme	healthy	205:211	arg1	food					213:216	a healthy food	203:216	a healthy food with a high content of bioactive compounds	203:259	Asparagus is considered a healthy food with a high content of bioactive compounds.					
36596190	6	51	theme	spear	804:808	arg1	by-product					810:819	the spear by-product	800:819	the spear by-product	800:819	It has been shown that the spear by-product can be selectively used to promote the growth of commensal or probiotic lactobacilli and bifidobacteria strains.					
36596190	3	52	theme	bacteria	486:493	arg1	growth					455:460	the growth	451:460	the growth of human gut-associated bacteria	451:493	Their activity on the growth of human gut-associated bacteria has been studied.					
36596190	0	53	from	assessment	104:113	arg1	growth					138:143	the growth	134:143	the growth of human gut-associated bacteria	134:176	Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria.					
36596190	7	54	theme	health-promoting	1034:1049	arg1	ingredients					1051:1061	health-promoting ingredients	1034:1061	health-promoting ingredients	1034:1061	It has been confirmed that any part of the asparagus has a potential future as a healthy food or as health-promoting ingredients, however more work is required to identify the compounds able to modulate the human gut microbiota.					
36596190	4	55	theme	asparagus	582:590	arg1	value					569:573	the high nutritional and functional value	533:573	the high nutritional and functional value of the asparagus, including its by-products	533:617	The results support the high nutritional and functional value of the asparagus, including its by-products, highlighting the potential of the non-edible parts to be used as prebiotics.					
36649861	0	0	theme	activation	105:114	arg1	degradation					134:144	activation peroxymonosulfate degradation	105:144	activation peroxymonosulfate degradation of organic dyes	105:160	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	6	1	theme	new	1324:1326	arg1	idea					1328:1331	a new idea	1322:1331	a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs)	1322:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	1	2	theme	oxidation	183:191	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	3	theme	graphene	270:277	arg1	oxide					279:283	reduced graphene oxide	262:283	reduced graphene oxide (rGO)	262:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	3	theme	graphene	270:277	arg1	rGO					286:288	rGO	286:288	rGO	286:288	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	4	theme	growth	569:574	arg1	model					576:580	a template-directed growth model	549:580	a template-directed growth model	549:580	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	1	5	theme	imidazolate	357:367	arg1	growth					338:343	facile in-situ growth	323:343	facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67)	323:389	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	6	theme	catalyst	193:200	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	4	7	theme	PMS	949:951	arg1	combination					913:923	the combination	909:923	the combination of catalyst aerogel and PMS	909:951	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	6	8	theme	oxidation	1408:1416	arg1	SR-AOPs					1429:1435	SR-AOPs	1429:1435	SR-AOPs	1429:1435	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	8	theme	oxidation	1408:1416	arg1	processes					1418:1426	sulfate radical-based advanced oxidation processes	1377:1426	sulfate radical-based advanced oxidation processes (SR-AOPs)	1377:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	0	9	theme	peroxymonosulfate	116:132	arg1	degradation					134:144	activation peroxymonosulfate degradation	105:144	activation peroxymonosulfate degradation of organic dyes	105:160	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	3	10	used	used	674:677	arg2	catalyst					695:702	an efficient catalyst	682:702	an efficient catalyst for activating peroxymonosulfate (PMS)	682:741	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	3	10	used	used	674:677	arg2	composite					647:655	The sustainable composite	631:655	The sustainable composite	631:655	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	5	11	dep	9	1022:1022	arg1	to					1019:1020	to	1019:1020	to	1019:1020	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	0	12	theme	organic	149:155	arg1	dyes					157:160	organic dyes	149:160	organic dyes	149:160	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	4	13	theme	10 ppm MB/RhB	850:862	arg1	solution					864:871	10 ppm MB/RhB solution	850:871	10 ppm MB/RhB solution	850:871	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	2	14	theme	methyl	431:436	arg1	acid					461:464	methyl vinyl ether-alt-maleic acid	431:464	methyl vinyl ether-alt-maleic acid	431:464	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	14	theme	methyl	431:436	arg1	poly					425:428	poly	425:428	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	6	15	theme	wastewater	1350:1359	arg1	purification					1361:1372	the compound wastewater purification	1337:1372	the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs)	1337:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	1	16	theme	ZIF-67	202:207	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	17	theme	glycol	480:485	arg1	system					487:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system	425:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	17	theme	glycol	480:485	arg1	PMVEMA/PEG					495:504	PMVEMA/PEG	495:504	PMVEMA/PEG	495:504	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	5	18	theme	contaminant	1057:1067	arg1	rate					1077:1080	the contaminant removal rate	1053:1080	the contaminant removal rate	1053:1080	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	6	19	theme	degradation	1204:1214	arg1	performance					1216:1226	excellent catalytic degradation performance	1184:1226	excellent catalytic degradation performance	1184:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	20	theme	radical-based	1385:1397	arg1	SR-AOPs					1429:1435	SR-AOPs	1429:1435	SR-AOPs	1429:1435	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	20	theme	radical-based	1385:1397	arg1	processes					1418:1426	sulfate radical-based advanced oxidation processes	1377:1426	sulfate radical-based advanced oxidation processes (SR-AOPs)	1377:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	1	21	theme	@	208:208	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	22	theme	/polyethylene	466:478	arg1	system					487:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system	425:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	22	theme	/polyethylene	466:478	arg1	PMVEMA/PEG					495:504	PMVEMA/PEG	495:504	PMVEMA/PEG	495:504	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	5	23	theme	removal	1069:1075	arg1	rate					1077:1080	the contaminant removal rate	1053:1080	the contaminant removal rate	1053:1080	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	6	24	theme	catalytic	1194:1202	arg1	performance					1216:1226	excellent catalytic degradation performance	1184:1226	excellent catalytic degradation performance	1184:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	25	theme	dispersion	1259:1268	arg1	problem					1248:1254	the problem	1244:1254	the problem of dispersion and recovery of ZIF-67 particles	1244:1301	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	0	26	theme	Template-directed	0:16	arg1	growth					18:23	Template-directed growth	0:23	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels	0:77	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	6	27	theme	particles	1293:1301	arg1	dispersion					1259:1268	dispersion	1259:1268	dispersion	1259:1268	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	27	theme	particles	1293:1301	arg1	recovery					1274:1281	recovery	1274:1281	recovery	1274:1281	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	4	28	theme	solution	864:871	arg1	solution					864:871	10 ppm MB/RhB solution	850:871	10 ppm MB/RhB solution	850:871	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	4	28	theme	solution	864:871	arg1	result					826:831	a result	824:831	a result	824:831	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	4	28	theme	solution	864:871	arg1	%					845:845	almost 100 %	834:845	almost 100 % of 10 ppm MB/RhB solution	834:871	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	3	29	theme	contaminants	807:818	arg1	removal					788:794	the removal	784:794	the removal of organic contaminants	784:818	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	2	30	theme	C-CMC/rGO	392:400	arg1	aerogel					402:408	C-CMC/rGO aerogel	392:408	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material	392:526	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	0	31	theme	sustainable	28:38	arg1	aerogels					70:77	sustainable carboxymethyl cellulose-based aerogels	28:77	sustainable carboxymethyl cellulose-based aerogels	28:77	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	6	32	theme	C-CMC/rGO	1142:1150	arg1	aerogel					1152:1158	The ZIF-67@C-CMC/rGO aerogel	1131:1158	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance	1131:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	4	33	theme	catalyst	928:935	arg1	aerogel					937:943	catalyst aerogel	928:943	catalyst aerogel	928:943	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	2	34	theme	vinyl	438:442	arg1	acid					461:464	methyl vinyl ether-alt-maleic acid	431:464	methyl vinyl ether-alt-maleic acid	431:464	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	34	theme	vinyl	438:442	arg1	poly					425:428	poly	425:428	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	35	theme	ether-alt-maleic	444:459	arg1	acid					461:464	methyl vinyl ether-alt-maleic acid	431:464	methyl vinyl ether-alt-maleic acid	431:464	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	35	theme	ether-alt-maleic	444:459	arg1	poly					425:428	poly	425:428	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	0	36	theme	dyes	157:160	arg1	degradation					134:144	activation peroxymonosulfate degradation	105:144	activation peroxymonosulfate degradation of organic dyes	105:160	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	3	37	theme	efficient	685:693	arg1	catalyst					695:702	an efficient catalyst	682:702	an efficient catalyst for activating peroxymonosulfate (PMS)	682:741	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	3	37	theme	efficient	685:693	arg1	composite					647:655	The sustainable composite	631:655	The sustainable composite	631:655	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	1	38	theme	carboxymethyl	228:240	arg1	CMC					253:255	CMC	253:255	CMC	253:255	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	38	theme	carboxymethyl	228:240	arg1	cellulose					242:250	carboxymethyl cellulose	228:250	carboxymethyl cellulose (CMC)	228:256	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	0	39	theme	cellulose-based	54:68	arg1	aerogels					70:77	sustainable carboxymethyl cellulose-based aerogels	28:77	sustainable carboxymethyl cellulose-based aerogels	28:77	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	3	40	dep	generate	746:753	arg1	leads					775:779	leads	775:779	leads to the removal of organic contaminants	775:818	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	2	41	theme	template-directed	551:567	arg1	model					576:580	a template-directed growth model	549:580	a template-directed growth model	549:580	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	5	42	theme	tolerance	996:1004	arg1	range					1006:1010	a wide pH tolerance range	986:1010	a wide pH tolerance range	986:1010	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	0	43	theme	carboxymethyl	40:52	arg1	aerogels					70:77	sustainable carboxymethyl cellulose-based aerogels	28:77	sustainable carboxymethyl cellulose-based aerogels	28:77	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	3	44	theme	organic	799:805	arg1	contaminants					807:818	organic contaminants	799:818	organic contaminants	799:818	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	4	45	theme	aerogel	937:943	arg1	combination					913:923	the combination	909:923	the combination of catalyst aerogel and PMS	909:951	As a result, almost 100 % of 10 ppm MB/RhB solution can be degraded within 5 min due to the combination of catalyst aerogel and PMS.					
36649861	3	46	theme	sustainable	635:645	arg1	catalyst					695:702	an efficient catalyst	682:702	an efficient catalyst for activating peroxymonosulfate (PMS)	682:741	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	3	46	theme	sustainable	635:645	arg1	composite					647:655	The sustainable composite	631:655	The sustainable composite	631:655	The sustainable composite was successfully used as an efficient catalyst for activating peroxymonosulfate (PMS) to generate SO4-· and ·OH, then leads to the removal of organic contaminants.					
36649861	2	47	theme	poly	425:428	arg1	system					487:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system	425:492	poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG)	425:505	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	2	47	theme	poly	425:428	arg1	PMVEMA/PEG					495:504	PMVEMA/PEG	495:504	PMVEMA/PEG	495:504	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	6	48	theme	compound	1341:1348	arg1	purification					1361:1372	the compound wastewater purification	1337:1372	the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs)	1337:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	1	49	theme	facile	323:328	arg1	growth					338:343	facile in-situ growth	323:343	facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67)	323:389	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	50	theme	mechanical	608:617	arg1	properties					619:628	outstanding mechanical properties	596:628	outstanding mechanical properties	596:628	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	6	51	theme	load	1170:1173	arg1	rate					1175:1178	high load rate	1165:1178	high load rate	1165:1178	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	52	theme	excellent	1184:1192	arg1	performance					1216:1226	excellent catalytic degradation performance	1184:1226	excellent catalytic degradation performance	1184:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	0	53	theme	aerogels	70:77	arg1	growth					18:23	Template-directed growth	0:23	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels	0:77	Template-directed growth of sustainable carboxymethyl cellulose-based aerogels decorated with ZIF-67 for activation peroxymonosulfate degradation of organic dyes.					
36649861	1	54	theme	in-situ	330:336	arg1	growth					338:343	facile in-situ growth	323:343	facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67)	323:389	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	55	theme	outstanding	596:606	arg1	properties					619:628	outstanding mechanical properties	596:628	outstanding mechanical properties	596:628	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	6	56	theme	high	1165:1168	arg1	rate					1175:1178	high load rate	1165:1178	high load rate	1165:1178	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	5	57	theme	initial	1098:1104	arg1	value					1106:1110	the initial value	1094:1110	the initial value after four cycles	1094:1128	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	6	58	theme	@	1141:1141	arg1	aerogel					1152:1158	The ZIF-67@C-CMC/rGO aerogel	1131:1158	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance	1131:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	59	with	aerogel	1152:1158	arg1	performance					1216:1226	excellent catalytic degradation performance	1184:1226	excellent catalytic degradation performance	1184:1226	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	59	with	aerogel	1152:1158	arg1	rate					1175:1178	high load rate	1165:1178	high load rate	1165:1178	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	60	theme	advanced	1399:1406	arg1	SR-AOPs					1429:1435	SR-AOPs	1429:1435	SR-AOPs	1429:1435	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	60	theme	advanced	1399:1406	arg1	processes					1418:1426	sulfate radical-based advanced oxidation processes	1377:1426	sulfate radical-based advanced oxidation processes (SR-AOPs)	1377:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	61	theme	recovery	1274:1281	arg1	problem					1248:1254	the problem	1244:1254	the problem of dispersion and recovery of ZIF-67 particles	1244:1301	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	5	62	dep	93 	1045:1047	arg1	to					1042:1043	to	1042:1043	to	1042:1043	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	6	63	from	purification	1361:1372	arg1	SR-AOPs					1429:1435	SR-AOPs	1429:1435	SR-AOPs	1429:1435	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	63	from	purification	1361:1372	arg1	processes					1418:1426	sulfate radical-based advanced oxidation processes	1377:1426	sulfate radical-based advanced oxidation processes (SR-AOPs)	1377:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	64	theme	ZIF-67	1286:1291	arg1	particles					1293:1301	ZIF-67 particles	1286:1301	ZIF-67 particles	1286:1301	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	1	65	theme	novel	165:169	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	2	66	theme	host	514:517	arg1	material					519:526	the host material	510:526	the host material	510:526	C-CMC/rGO aerogel crosslinked by poly (methyl vinyl ether-alt-maleic acid)/polyethylene glycol system (PMVEMA/PEG) as the host material was prepared through a template-directed growth model and exhibited outstanding mechanical properties.					
36649861	6	67	theme	sulfate	1377:1383	arg1	SR-AOPs					1429:1435	SR-AOPs	1429:1435	SR-AOPs	1429:1435	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	6	67	theme	sulfate	1377:1383	arg1	processes					1418:1426	sulfate radical-based advanced oxidation processes	1377:1426	sulfate radical-based advanced oxidation processes (SR-AOPs)	1377:1436	The ZIF-67@C-CMC/rGO aerogel with high load rate and excellent catalytic degradation performance not only solved the problem of dispersion and recovery of ZIF-67 particles, but also provided a new idea for the compound wastewater purification in sulfate radical-based advanced oxidation processes (SR-AOPs).					
36649861	5	68	theme	wide	988:991	arg1	range					1006:1010	a wide pH tolerance range	986:1010	a wide pH tolerance range	986:1010	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	1	69	theme	3D	171:172	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	5	70	theme	rate	1077:1080	arg1	rate					1077:1080	the contaminant removal rate	1053:1080	the contaminant removal rate	1053:1080	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	5	70	theme	rate	1077:1080	arg1	%					1048:1048	up to 93 %	1039:1048	up to 93 % of the contaminant removal rate	1039:1080	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	5	71	theme	pH	993:994	arg1	range					1006:1010	a wide pH tolerance range	986:1010	a wide pH tolerance range	986:1010	What's more, the aerogel showed a wide pH tolerance range from 4 to 9 and maintained up to 93 % of the contaminant removal rate compared to the initial value after four cycles.					
36649861	1	72	theme	advanced	174:181	arg1	C-CMC/rGO					209:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO	163:217	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO)	163:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	73	theme	reduced	262:268	arg1	oxide					279:283	reduced graphene oxide	262:283	reduced graphene oxide (rGO)	262:289	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
36649861	1	73	theme	reduced	262:268	arg1	rGO					286:288	rGO	286:288	rGO	286:288	A novel 3D advanced oxidation catalyst ZIF-67@C-CMC/rGO based on carboxymethyl cellulose (CMC) and reduced graphene oxide (rGO) was successfully synthesized by facile in-situ growth of Zeolitic imidazolate framework-67 (ZIF-67).					
35839641	3	0	theme	chemical	559:566	arg1	hydrogels					581:589	chemical cross-linked hydrogels	559:589	chemical cross-linked hydrogels	559:589	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	6	1	theme	release	1016:1022	arg1	behaviors					1024:1032	the release behaviors	1012:1032	the release behaviors of DOX⋅HCl	1012:1043	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	3	2	theme	cross-linked	568:579	arg1	hydrogels					581:589	chemical cross-linked hydrogels	559:589	chemical cross-linked hydrogels	559:589	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	3	theme	hydrogels	581:589	arg1	combination					517:527	The combination	513:527	The combination of magnetic nanoparticles and chemical cross-linked hydrogels	513:589	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	4	theme	dual-sensitive	612:625	arg1	carrier					677:683	stimuli-responsive carrier	658:683	stimuli-responsive carrier	658:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	4	theme	dual-sensitive	612:625	arg1	hydrogels					627:635	magnetic/pH dual-sensitive hydrogels	600:635	magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier	600:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	7	5	theme	various	1242:1248	arg1	release					1276:1282	drug release	1271:1282	drug release	1271:1282	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	7	5	theme	various	1242:1248	arg1	applications					1250:1261	various applications	1242:1261	various applications such as drug release	1242:1282	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	2	6	theme	oxide	318:322	arg1	Fe3O4					339:343	Fe3O4	339:343	Fe3O4	339:343	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	2	6	theme	oxide	318:322	arg1	nanoparticles					324:336	water-soluble superparamagnetic iron oxide nanoparticles	281:336	water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation	281:372	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	4	7	theme	Fe3O4	805:809	arg1	content					824:830	the Fe3O4 nanoparticle content	801:830	the Fe3O4 nanoparticle content	801:830	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	5	8	theme	release	932:938	arg1	profiles					940:947	pH/magnetic sensitive release profiles	910:947	pH/magnetic sensitive release profiles	910:947	Moreover, doxorubicin (DOX⋅HCl) was embedded into the magnetic hydrogels and pH/magnetic sensitive release profiles were identified.					
35839641	2	9	theme	iron	313:316	arg1	Fe3O4					339:343	Fe3O4	339:343	Fe3O4	339:343	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	2	9	theme	iron	313:316	arg1	nanoparticles					324:336	water-soluble superparamagnetic iron oxide nanoparticles	281:336	water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation	281:372	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	5	10	theme	magnetic	887:894	arg1	hydrogels					896:904	the magnetic hydrogels	883:904	the magnetic hydrogels	883:904	Moreover, doxorubicin (DOX⋅HCl) was embedded into the magnetic hydrogels and pH/magnetic sensitive release profiles were identified.					
35839641	2	11	theme	superparamagnetic	295:311	arg1	Fe3O4					339:343	Fe3O4	339:343	Fe3O4	339:343	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	2	11	theme	superparamagnetic	295:311	arg1	nanoparticles					324:336	water-soluble superparamagnetic iron oxide nanoparticles	281:336	water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation	281:372	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	7	12	with	composites	1155:1164	arg1	stimuli-responsiveness					1188:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	2	13	theme	oxidized	495:502	arg1	dextran					504:510	oxidized dextran	495:510	oxidized dextran	495:510	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	6	14	theme	mechanism	978:986	arg1	analysis					988:995	The release mechanism analysis	966:995	The release mechanism analysis	966:995	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	4	15	theme	magnetic	756:763	arg1	hydrogels					765:773	the resulted magnetic hydrogels	743:773	the resulted magnetic hydrogels	743:773	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	4	16	theme	resulted	747:754	arg1	hydrogels					765:773	the resulted magnetic hydrogels	743:773	the resulted magnetic hydrogels	743:773	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	0	17	theme	dual	25:28	arg1	dextran					41:47	magnetic/pH dual responsive dextran	13:47	magnetic/pH dual responsive dextran	13:47	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	1	18	theme	good	207:210	arg1	biocompatibility					212:227	their good biocompatibility	201:227	their good biocompatibility	201:227	Hydrogels loaded with magnetic nanoparticles have been widely researched recently as biomaterials, due to their good biocompatibility and unique magnetic characteristics.					
35839641	0	19	theme	magnetic/pH	13:23	arg1	dextran					41:47	magnetic/pH dual responsive dextran	13:47	magnetic/pH dual responsive dextran	13:47	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	3	20	link	cross-linked	568:579	arg1	hydrogels					581:589	chemical cross-linked hydrogels	559:589	chemical cross-linked hydrogels	559:589	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	6	21	theme	release	970:976	arg1	mechanism					978:986	The release mechanism	966:986	The release mechanism analysis	966:995	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	1	22	theme	magnetic	117:124	arg1	nanoparticles					126:138	magnetic nanoparticles	117:138	magnetic nanoparticles	117:138	Hydrogels loaded with magnetic nanoparticles have been widely researched recently as biomaterials, due to their good biocompatibility and unique magnetic characteristics.					
35839641	2	23	theme	base	452:455	arg1	reactions					457:465	Schiff base reactions	445:465	Schiff base reactions between ethylenediamine and oxidized dextran	445:510	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	0	24	theme	dextran	41:47	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of magnetic/pH dual responsive dextran	0:47	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	7	25	theme	magnetic/pH	1176:1186	arg1	stimuli-responsiveness					1188:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	2	26	theme	Schiff	445:450	arg1	reactions					457:465	Schiff base reactions	445:465	Schiff base reactions between ethylenediamine and oxidized dextran	445:510	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	3	27	used	used	650:653	arg2	hydrogels					627:635	magnetic/pH dual-sensitive hydrogels	600:635	magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier	600:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	27	used	used	650:653	arg2	carrier					677:683	stimuli-responsive carrier	658:683	stimuli-responsive carrier	658:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	0	28	theme	responsive	30:39	arg1	dextran					41:47	magnetic/pH dual responsive dextran	13:47	magnetic/pH dual responsive dextran	13:47	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	1	29	theme	unique	233:238	arg1	characteristics					249:263	unique magnetic characteristics	233:263	unique magnetic characteristics	233:263	Hydrogels loaded with magnetic nanoparticles have been widely researched recently as biomaterials, due to their good biocompatibility and unique magnetic characteristics.					
35839641	7	30	theme	prepared	1131:1138	arg1	composites					1155:1164	The prepared hydrogel/Fe3O4 composites	1127:1164	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness	1127:1209	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	3	31	theme	nanoparticles	541:553	arg1	combination					517:527	The combination	513:527	The combination of magnetic nanoparticles and chemical cross-linked hydrogels	513:589	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	7	32	theme	drug	1271:1274	arg1	release					1276:1282	drug release	1271:1282	drug release	1271:1282	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	7	33	theme	dual	1171:1174	arg1	stimuli-responsiveness					1188:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	dual magnetic/pH stimuli-responsiveness	1171:1209	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	6	34	dep	diffusion	1068:1076	arg1	processes					1101:1109	processes	1101:1109	processes	1101:1109	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	6	34	dep	diffusion	1068:1076	arg1	the					1064:1066	the	1064:1066	the	1064:1066	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	3	35	theme	stimuli-responsive	658:675	arg1	carrier					677:683	stimuli-responsive carrier	658:683	stimuli-responsive carrier	658:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	35	theme	stimuli-responsive	658:675	arg1	hydrogels					627:635	magnetic/pH dual-sensitive hydrogels	600:635	magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier	600:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	6	36	theme	DOX⋅HCl	1037:1043	arg1	behaviors					1024:1032	the release behaviors	1012:1032	the release behaviors of DOX⋅HCl	1012:1043	The release mechanism analysis indicated that the release behaviors of DOX⋅HCl were controlled by the diffusion, swelling, and erosion processes simultaneously.					
35839641	7	37	theme	hydrogel/Fe3O4	1140:1153	arg1	composites					1155:1164	The prepared hydrogel/Fe3O4 composites	1127:1164	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness	1127:1209	The prepared hydrogel/Fe3O4 composites with dual magnetic/pH stimuli-responsiveness hold the promise to be used in various applications such as drug release.					
35839641	2	38	theme	water-soluble	281:293	arg1	Fe3O4					339:343	Fe3O4	339:343	Fe3O4	339:343	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	2	38	theme	water-soluble	281:293	arg1	nanoparticles					324:336	water-soluble superparamagnetic iron oxide nanoparticles	281:336	water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation	281:372	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	4	39	theme	nanoparticle	811:822	arg1	content					824:830	the Fe3O4 nanoparticle content	801:830	the Fe3O4 nanoparticle content	801:830	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	1	40	theme	magnetic	240:247	arg1	characteristics					249:263	unique magnetic characteristics	233:263	unique magnetic characteristics	233:263	Hydrogels loaded with magnetic nanoparticles have been widely researched recently as biomaterials, due to their good biocompatibility and unique magnetic characteristics.					
35839641	3	41	theme	magnetic/pH	600:610	arg1	carrier					677:683	stimuli-responsive carrier	658:683	stimuli-responsive carrier	658:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	41	theme	magnetic/pH	600:610	arg1	hydrogels					627:635	magnetic/pH dual-sensitive hydrogels	600:635	magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier	600:683	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	3	42	theme	magnetic	532:539	arg1	nanoparticles					541:553	magnetic nanoparticles	532:553	magnetic nanoparticles	532:553	The combination of magnetic nanoparticles and chemical cross-linked hydrogels leads to magnetic/pH dual-sensitive hydrogels which can be used as stimuli-responsive carrier.					
35839641	4	43	theme	Magnetic	686:693	arg1	properties					695:704	Magnetic properties	686:704	Magnetic properties	686:704	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	0	44	theme	drug	80:83	arg1	carriers					85:92	stimuli-sensitive drug carriers	62:92	stimuli-sensitive drug carriers	62:92	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	4	45	theme	rheology	721:728	arg1	behaviors					730:738	rheology behaviors	721:738	rheology behaviors	721:738	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	5	46	theme	sensitive	922:930	arg1	profiles					940:947	pH/magnetic sensitive release profiles	910:947	pH/magnetic sensitive release profiles	910:947	Moreover, doxorubicin (DOX⋅HCl) was embedded into the magnetic hydrogels and pH/magnetic sensitive release profiles were identified.					
35839641	2	47	theme	dextran	405:411	arg1	hydrogels					413:421	the dextran hydrogels	401:421	the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran	401:510	In this study, water-soluble superparamagnetic iron oxide nanoparticles (Fe3O4) prepared by coprecipitation were physically doped into the dextran hydrogels which were formed via Schiff base reactions between ethylenediamine and oxidized dextran.					
35839641	0	48	theme	stimuli-sensitive	62:78	arg1	carriers					85:92	stimuli-sensitive drug carriers	62:92	stimuli-sensitive drug carriers	62:92	Synthesis of magnetic/pH dual responsive dextran hydrogels as stimuli-sensitive drug carriers.					
35839641	5	49	theme	pH/magnetic	910:920	arg1	profiles					940:947	pH/magnetic sensitive release profiles	910:947	pH/magnetic sensitive release profiles	910:947	Moreover, doxorubicin (DOX⋅HCl) was embedded into the magnetic hydrogels and pH/magnetic sensitive release profiles were identified.					
35839641	4	50	theme	hydrogels	765:773	arg1	properties					695:704	Magnetic properties	686:704	Magnetic properties	686:704	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	4	50	theme	hydrogels	765:773	arg1	behaviors					730:738	rheology behaviors	721:738	rheology behaviors	721:738	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35839641	4	50	theme	hydrogels	765:773	arg1	swelling					707:714	swelling	707:714	swelling	707:714	Magnetic properties, swelling, and rheology behaviors of the resulted magnetic hydrogels were strongly affected by the Fe3O4 nanoparticle content.					
35278516	0	0	theme	tainted	91:97	arg1	treatment					105:113	tainted water treatment	91:113	tainted water treatment	91:113	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	8	1	theme	catalytic	961:969	arg1	highest					998:1004	highest	998:1004	highest	998:1004	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	8	1	theme	catalytic	961:969	arg1	performance					971:981	the catalytic performance	957:981	the catalytic performance of Cu0/AGL	957:992	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	1	2	theme	different	162:170	arg1	pollutants					176:185	different dye pollutants	162:185	different dye pollutants which demands an instant solution	162:219	Water pollution reached worrying point due to different dye pollutants which demands an instant solution.					
35278516	12	3	theme	easy	1630:1633	arg1	separation					1635:1644	their easy separation	1624:1644	their easy separation	1624:1644	With the use of AGL as support for the Cu nanoparticles, not only the catalytic activity was retained for longer times during reusability, but it helped in their easy separation.					
35278516	12	4	theme	Cu	1507:1508	arg1	nanoparticles					1510:1522	the Cu nanoparticles	1503:1522	the Cu nanoparticles	1503:1522	With the use of AGL as support for the Cu nanoparticles, not only the catalytic activity was retained for longer times during reusability, but it helped in their easy separation.					
35278516	8	5	theme	kinetics	1028:1035	arg1	terms					1009:1013	terms	1009:1013	terms of reduction kinetics	1009:1035	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	8	6	theme	Cu0/AGL	986:992	arg1	highest					998:1004	highest	998:1004	highest	998:1004	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	8	6	theme	Cu0/AGL	986:992	arg1	performance					971:981	the catalytic performance	957:981	the catalytic performance of Cu0/AGL	957:992	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	1	7	theme	dye	172:174	arg1	pollutants					176:185	different dye pollutants	162:185	different dye pollutants which demands an instant solution	162:219	Water pollution reached worrying point due to different dye pollutants which demands an instant solution.					
35278516	9	8	theme	different	1066:1074	arg1	pollutants					1076:1085	different pollutants	1066:1085	different pollutants	1066:1085	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	11	9	theme	catalysts	1420:1428	arg1	reusability					1393:1403	The reusability	1389:1403	The reusability of the Cu0/AGL catalysts up to the 7th cycle	1389:1448	The reusability of the Cu0/AGL catalysts up to the 7th cycle has been checked.					
35278516	4	10	theme	effective	506:514	arg1	nanoparticles					476:488	Metal nanoparticles	470:488	Metal nanoparticles (M0)	470:493	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	4	10	theme	effective	506:514	arg1	catalysts					516:524	highly effective catalysts	499:524	highly effective catalysts	499:524	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	4	11	theme	high-speed	601:610	arg1	centrifugation					612:625	a high-speed centrifugation	599:625	a high-speed centrifugation	599:625	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	0	12	theme	water	99:103	arg1	treatment					105:113	tainted water treatment	91:113	tainted water treatment	91:113	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	9	13	theme	catalyst	1185:1192	arg1	dosage					1194:1199	catalyst dosage	1185:1199	catalyst dosage	1185:1199	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	13	theme	catalyst	1185:1192	arg1	parameters					1168:1177	all optimized different parameters	1144:1177	all optimized different parameters i.e.	1144:1182	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	6	14	theme	leucine	736:742	arg1	hybrid-beads					750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads	712:761	hybrid-beads	750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	7	15	theme	M0/AGL	845:850	arg1	catalysts					857:865	M0/AGL bead catalysts	845:865	M0/AGL bead catalysts	845:865	M0/AGL bead catalysts were tested toward reducing various toxic compounds.					
35278516	7	16	theme	bead	852:855	arg1	catalysts					857:865	M0/AGL bead catalysts	845:865	M0/AGL bead catalysts	845:865	M0/AGL bead catalysts were tested toward reducing various toxic compounds.					
35278516	10	17	theme	high-rate	1307:1315	arg1	kapp					1328:1331	kapp	1328:1331	kapp	1328:1331	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	10	17	theme	high-rate	1307:1315	arg1	constants					1317:1325	high-rate constants	1307:1325	high-rate constants (kapp) of 0.7566 and 2.9506 min-1	1307:1359	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	9	18	theme	initial	1044:1050	arg1	screening					1052:1060	initial screening	1044:1060	initial screening for different pollutants	1044:1085	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	6	19	theme	alginate/glycyl	720:734	arg1	hybrid-beads					750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads	712:761	hybrid-beads	750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	3	20	theme	such	436:439	arg1	pollutants					441:450	such pollutants	436:450	such pollutants	436:450	However, reduction process requires an effective, stable, and recyclable catalyst to reduce such pollutants more effectively.					
35278516	3	21	theme	reduction	353:361	arg1	process					363:369	reduction process	353:369	reduction process	353:369	However, reduction process requires an effective, stable, and recyclable catalyst to reduce such pollutants more effectively.					
35278516	3	22	theme	stable	394:399	arg1	catalyst					417:424	an effective, stable, and recyclable catalyst	380:424	an effective, stable, and recyclable catalyst to reduce such pollutants more effectively	380:467	However, reduction process requires an effective, stable, and recyclable catalyst to reduce such pollutants more effectively.					
35278516	0	23	theme	Cu	18:19	arg1	catalysts					27:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	6	24	theme	Hearin	712:717	arg1	hybrid-beads					750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads	712:761	hybrid-beads	750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	0	25	theme	Nanoarchitectured	0:16	arg1	catalysts					27:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	8	26	theme	reduction	1018:1026	arg1	kinetics					1028:1035	reduction kinetics	1018:1035	reduction kinetics	1018:1035	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	2	27	theme	less-toxic	311:320	arg1	compounds					333:341	less-toxic and useful compounds	311:341	less-toxic and useful compounds	311:341	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	11	28	theme	7th	1440:1442	arg1	cycle					1444:1448	the 7th cycle	1436:1448	the 7th cycle	1436:1448	The reusability of the Cu0/AGL catalysts up to the 7th cycle has been checked.					
35278516	12	29	theme	AGL	1484:1486	arg1	use					1477:1479	the use	1473:1479	the use of AGL as support for the Cu nanoparticles	1473:1522	With the use of AGL as support for the Cu nanoparticles, not only the catalytic activity was retained for longer times during reusability, but it helped in their easy separation.					
35278516	12	30	theme	longer	1574:1579	arg1	times					1581:1585	longer times	1574:1585	longer times during reusability	1574:1604	With the use of AGL as support for the Cu nanoparticles, not only the catalytic activity was retained for longer times during reusability, but it helped in their easy separation.					
35278516	6	31	theme	copper	782:787	arg1	Cu0					804:806	Cu0	804:806	Cu0	804:806	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	6	31	theme	copper	782:787	arg1	nanoparticles					789:801	copper nanoparticles	782:801	copper nanoparticles (Cu0)	782:807	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	1	32	theme	instant	204:210	arg1	solution					212:219	an instant solution	201:219	an instant solution	201:219	Water pollution reached worrying point due to different dye pollutants which demands an instant solution.					
35278516	3	33	theme	effective	383:391	arg1	catalyst					417:424	an effective, stable, and recyclable catalyst	380:424	an effective, stable, and recyclable catalyst to reduce such pollutants more effectively	380:467	However, reduction process requires an effective, stable, and recyclable catalyst to reduce such pollutants more effectively.					
35278516	1	34	theme	Water	116:120	arg1	pollution					122:130	Water pollution	116:130	Water pollution	116:130	Water pollution reached worrying point due to different dye pollutants which demands an instant solution.					
35278516	3	35	theme	recyclable	406:415	arg1	catalyst					417:424	an effective, stable, and recyclable catalyst	380:424	an effective, stable, and recyclable catalyst to reduce such pollutants more effectively	380:467	However, reduction process requires an effective, stable, and recyclable catalyst to reduce such pollutants more effectively.					
35278516	9	36	theme	reducing-agent	1223:1236	arg1	recyclability					1242:1254	recyclability	1242:1254	recyclability	1242:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	36	theme	reducing-agent	1223:1236	arg1	parameters					1168:1177	all optimized different parameters	1144:1177	all optimized different parameters i.e.	1144:1182	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	36	theme	reducing-agent	1223:1236	arg1	reducing-agent					1223:1236	reducing-agent	1223:1236	reducing-agent	1223:1236	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	36	theme	reducing-agent	1223:1236	arg1	amount					1213:1218	amount	1213:1218	amount of reducing-agent and recyclability	1213:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	2	37	theme	ways	238:241	arg1	ways					238:241	the best ways	229:241	the best ways to manage water pollutants	229:268	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	2	37	theme	ways	238:241	arg1	One					222:224	One	222:224	One	222:224	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	9	38	theme	MO	1124:1125	arg1	reduction					1127:1135	MO reduction	1124:1135	MO reduction	1124:1135	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	4	39	theme	Metal	470:474	arg1	M0					491:492	M0	491:492	M0	491:492	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	4	39	theme	Metal	470:474	arg1	nanoparticles					476:488	Metal nanoparticles	470:488	Metal nanoparticles (M0)	470:493	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	4	39	theme	Metal	470:474	arg1	catalysts					516:524	highly effective catalysts	499:524	highly effective catalysts	499:524	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	2	40	theme	best	233:236	arg1	ways					238:241	the best ways	229:241	the best ways to manage water pollutants	229:268	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	10	41	theme	2.9506 min-1	1348:1359	arg1	kapp					1328:1331	kapp	1328:1331	kapp	1328:1331	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	10	41	theme	2.9506 min-1	1348:1359	arg1	constants					1317:1325	high-rate constants	1307:1325	high-rate constants (kapp) of 0.7566 and 2.9506 min-1	1307:1359	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	11	42	theme	Cu0/AGL	1412:1418	arg1	catalysts					1420:1428	the Cu0/AGL catalysts	1408:1428	the Cu0/AGL catalysts	1408:1428	The reusability of the Cu0/AGL catalysts up to the 7th cycle has been checked.					
35278516	0	43	theme	leucine	66:72	arg1	beads					81:85	alginate/glycyl leucine hybrid beads	50:85	alginate/glycyl leucine hybrid beads for tainted water treatment	50:113	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	9	44	theme	recyclability	1242:1254	arg1	recyclability					1242:1254	recyclability	1242:1254	recyclability	1242:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	44	theme	recyclability	1242:1254	arg1	parameters					1168:1177	all optimized different parameters	1144:1177	all optimized different parameters i.e.	1144:1182	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	44	theme	recyclability	1242:1254	arg1	reducing-agent					1223:1236	reducing-agent	1223:1236	reducing-agent	1223:1236	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	44	theme	recyclability	1242:1254	arg1	amount					1213:1218	amount	1213:1218	amount of reducing-agent and recyclability	1213:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	0	45	theme	alginate/glycyl	50:64	arg1	beads					81:85	alginate/glycyl leucine hybrid beads	50:85	alginate/glycyl leucine hybrid beads for tainted water treatment	50:113	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	4	46	theme	nanoparticles	544:556	arg1	separation					530:539	separation	530:539	separation of nanoparticles after reaction	530:571	Metal nanoparticles (M0) are highly effective catalysts but separation of nanoparticles after reaction is difficult and requires a high-speed centrifugation.					
35278516	10	47	theme	0.7566	1337:1342	arg1	kapp					1328:1331	kapp	1328:1331	kapp	1328:1331	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	10	47	theme	0.7566	1337:1342	arg1	constants					1317:1325	high-rate constants	1307:1325	high-rate constants (kapp) of 0.7566 and 2.9506 min-1	1307:1359	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	6	48	theme	simple	829:834	arg1	process					836:842	simple process	829:842	simple process	829:842	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
35278516	8	49	theme	developed	930:938	arg1	composite-beads					940:954	all developed composite-beads	926:954	all developed composite-beads	926:954	Among all developed composite-beads, the catalytic performance of Cu0/AGL was highest in terms of reduction kinetics.					
35278516	1	50	theme	worrying	140:147	arg1	point					149:153	worrying point	140:153	worrying point	140:153	Water pollution reached worrying point due to different dye pollutants which demands an instant solution.					
35278516	9	51	theme	different	1158:1166	arg1	dosage					1194:1199	catalyst dosage	1185:1199	catalyst dosage	1185:1199	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	51	theme	different	1158:1166	arg1	reducing-agent					1223:1236	reducing-agent	1223:1236	reducing-agent	1223:1236	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	51	theme	different	1158:1166	arg1	recyclability					1242:1254	recyclability	1242:1254	recyclability	1242:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	51	theme	different	1158:1166	arg1	parameters					1168:1177	all optimized different parameters	1144:1177	all optimized different parameters i.e.	1144:1182	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	51	theme	different	1158:1166	arg1	stability					1202:1210	stability	1202:1210	stability	1202:1210	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	51	theme	different	1158:1166	arg1	amount					1213:1218	amount	1213:1218	amount of reducing-agent and recyclability	1213:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	11	52	dep	cycle	1444:1448	arg1	up					1430:1431	up	1430:1431	up	1430:1431	The reusability of the Cu0/AGL catalysts up to the 7th cycle has been checked.					
35278516	2	53	theme	water	253:257	arg1	pollutants					259:268	water pollutants	253:268	water pollutants	253:268	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	2	54	theme	useful	326:331	arg1	compounds					333:341	less-toxic and useful compounds	311:341	less-toxic and useful compounds	311:341	One of the best ways to manage water pollutants is their reduction and decolorization to less-toxic and useful compounds.					
35278516	7	55	theme	various	895:901	arg1	compounds					909:917	various toxic compounds	895:917	various toxic compounds	895:917	M0/AGL bead catalysts were tested toward reducing various toxic compounds.					
35278516	10	56	theme	beads	1374:1378	arg1	content					1380:1386	beads content	1374:1386	beads content	1374:1386	The Cu0/AGL showed high-rate constants (kapp) of 0.7566 and 2.9506 min-1 depending on beads content.					
35278516	9	57	theme	optimized	1148:1156	arg1	dosage					1194:1199	catalyst dosage	1185:1199	catalyst dosage	1185:1199	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	57	theme	optimized	1148:1156	arg1	reducing-agent					1223:1236	reducing-agent	1223:1236	reducing-agent	1223:1236	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	57	theme	optimized	1148:1156	arg1	recyclability					1242:1254	recyclability	1242:1254	recyclability	1242:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	57	theme	optimized	1148:1156	arg1	parameters					1168:1177	all optimized different parameters	1144:1177	all optimized different parameters i.e.	1144:1182	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	57	theme	optimized	1148:1156	arg1	stability					1202:1210	stability	1202:1210	stability	1202:1210	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	9	57	theme	optimized	1148:1156	arg1	amount					1213:1218	amount	1213:1218	amount of reducing-agent and recyclability	1213:1254	After initial screening for different pollutants, Cu0/AGL was much more effective for MO reduction, thus, all optimized different parameters i.e., catalyst dosage, stability, amount of reducing-agent and recyclability were experimentally determined.					
35278516	7	58	theme	toxic	903:907	arg1	compounds					909:917	various toxic compounds	895:917	various toxic compounds	895:917	M0/AGL bead catalysts were tested toward reducing various toxic compounds.					
35278516	12	59	theme	catalytic	1538:1546	arg1	activity					1548:1555	not only the catalytic activity	1525:1555	not only the catalytic activity	1525:1555	With the use of AGL as support for the Cu nanoparticles, not only the catalytic activity was retained for longer times during reusability, but it helped in their easy separation.					
35278516	0	60	theme	hybrid	74:79	arg1	beads					81:85	alginate/glycyl leucine hybrid beads	50:85	alginate/glycyl leucine hybrid beads for tainted water treatment	50:113	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	0	61	theme	based	21:25	arg1	catalysts					27:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts	0:35	Nanoarchitectured Cu based catalysts supported on alginate/glycyl leucine hybrid beads for tainted water treatment.					
35278516	6	62	theme	AGL	745:747	arg1	hybrid-beads					750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads	712:761	hybrid-beads	750:761	Hearin, alginate/glycyl leucine (AGL) hybrid-beads were prepared, and copper nanoparticles (Cu0) were grown on it by simple process.					
36379167	8	0	theme	apparent	1135:1142	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	0	theme	apparent	1135:1142	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	0	theme	apparent	1135:1142	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	5	1	theme	H2O/EtOH-extracted	622:639	arg1	SCB					641:643	the H2O/EtOH-extracted SCB	618:643	the H2O/EtOH-extracted SCB	618:643	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	5	1	theme	H2O/EtOH-extracted	622:639	arg1	in-situ					649:655	in-situ	649:655	in-situ impregnated with a bimetallic solution of copper and silver nitrates	649:724	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	8	2	theme	pseudo-second	1100:1112	arg1	rate					1120:1123	the pseudo-second order rate	1096:1123	the pseudo-second order rate	1096:1123	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	3	theme	degradation	1144:1154	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	3	theme	degradation	1144:1154	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	3	theme	degradation	1144:1154	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	10	4	dep	Trypanosoma	1363:1373	arg1	cruzi					1375:1379	cruzi	1375:1379	cruzi	1375:1379	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	4	5	theme	natural	560:566	arg1	extract					568:574	the natural extract	556:574	the natural extract that served as bio-reducing medium	556:609	The SCB was first macerated and ultrasonicated to obtain the natural extract that served as bio-reducing medium.					
36379167	8	6	dep	constants	1161:1169	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	6	dep	constants	1161:1169	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	6	dep	constants	1161:1169	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	12	7	theme	6th	1739:1741	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	7	theme	6th	1739:1741	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	7	theme	6th	1739:1741	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	11	8	dep	Trypanosoma	1568:1578	arg1	cruzi					1580:1584	cruzi	1580:1584	cruzi	1580:1584	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	5	9	theme	silver	710:715	arg1	solution					687:694	a bimetallic solution	674:694	a bimetallic solution of copper and silver nitrates	674:724	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	8	10	with	laws	1125:1128	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	10	with	laws	1125:1128	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	10	with	laws	1125:1128	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	11	11	theme	3.580 ± 0.016	1497:1509	arg1	values					1472:1477	IC50 values	1467:1477	IC50 values	1467:1477	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	0	12	theme	sugarcane	98:106	arg1	bagasse					108:114	sugarcane bagasse	98:114	sugarcane bagasse	98:114	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	11	13	theme	exceptional	1410:1420	arg1	effects					1454:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	12	14	theme	sustainable	1776:1786	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	14	theme	sustainable	1776:1786	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	14	theme	sustainable	1776:1786	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	6	15	theme	Ag/Cu-Ag+/Cu2+-loaded	781:801	arg1	composite					764:772	an intermediate composite	748:772	an intermediate composite (FM0)	748:778	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	6	15	theme	Ag/Cu-Ag+/Cu2+-loaded	781:801	arg1	SCB					803:805	Ag/Cu-Ag+/Cu2+-loaded SCB	781:805	Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste	781:946	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	12	16	theme	3rd	1713:1715	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	16	theme	3rd	1713:1715	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	16	theme	3rd	1713:1715	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	10	17	theme	new	1261:1263	arg1	materials					1284:1292	new anti-kinetoplastid materials	1261:1292	new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi	1261:1379	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	17	theme	new	1261:1263	arg1	FM0					1229:1231	FM0	1229:1231	FM0	1229:1231	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	17	theme	new	1261:1263	arg1	FM2					1242:1244	FM2	1242:1244	FM2	1242:1244	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	17	theme	new	1261:1263	arg1	FM1					1234:1236	FM1	1234:1236	FM1	1234:1236	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	12	18	theme	United	1761:1766	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	18	theme	United	1761:1766	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	18	theme	United	1761:1766	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	8	19	theme	K1	1171:1172	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	19	theme	K1	1171:1172	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	6	20	theme	Ag/Cu	867:871	arg1	FM2					888:890	FM2	888:890	FM2	888:890	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	6	20	theme	Ag/Cu	867:871	arg1	nanoparticles					873:885	free Ag/Cu nanoparticles	862:885	free Ag/Cu nanoparticles (FM2)	862:891	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	11	21	theme	3.020 ± 0.372 ppm	1515:1531	arg1	values					1472:1477	IC50 values	1467:1477	IC50 values	1467:1477	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	2	22	theme	Biochar	279:285	arg1	preparation					287:297	Biochar preparation	279:297	Biochar preparation	279:297	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	11	23	theme	leishmanicidal	1422:1435	arg1	effects					1454:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	6	24	theme	free	862:865	arg1	FM2					888:890	FM2	888:890	FM2	888:890	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	6	24	theme	free	862:865	arg1	nanoparticles					873:885	free Ag/Cu nanoparticles	862:885	free Ag/Cu nanoparticles (FM2)	862:891	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	12	25	dep	3rd	1713:1715	arg1	indicator					1718:1726	indicator 3.3.5	1718:1732	indicator 3.3.5	1718:1732	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	25	dep	3rd	1713:1715	arg1	indicator					1744:1752	indicator 6.3.1	1744:1758	indicator 6.3.1	1744:1758	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	8	26	theme	pseudo-first	1079:1090	arg1	laws					1125:1128	the pseudo-first and the pseudo-second order rate laws	1075:1128	the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1075:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	27	theme	10-3	1177:1180	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	27	theme	10-3	1177:1180	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	28	theme	experimental	1048:1059	arg1	data					1061:1064	The experimental data	1044:1064	The experimental data	1044:1064	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	5	29	dep	copper	699:704	arg1	nitrates					717:724	nitrates	717:724	nitrates	717:724	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	12	30	theme	″Good	1807:1811	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	30	theme	″Good	1807:1811	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	2	31	theme	functional	388:397	arg1	material					399:406	high added-value functional material	371:406	high added-value functional material (FM)	371:411	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	2	31	theme	functional	388:397	arg1	FM					409:410	FM	409:410	FM	409:410	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	0	32	theme	Green	0:4	arg1	pathway					18:24	Green, zero-waste pathway	0:24	pathway	18:24	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	10	33	dep	spp	1351:1353	arg1	the					1336:1338	the	1336:1338	the	1336:1338	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	2	34	theme	practical	312:320	arg1	solutions					322:330	the practical solutions	308:330	the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM)	308:411	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	10	35	dep	protozoans	1318:1327	arg1	spp					1351:1353	Leishmania spp	1340:1353	Leishmania spp	1340:1353	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	35	dep	protozoans	1318:1327	arg1	Trypanosoma					1363:1373	Trypanosoma	1363:1373	Trypanosoma	1363:1373	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	2	36	theme	added-value	376:386	arg1	material					399:406	high added-value functional material	371:406	high added-value functional material (FM)	371:411	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	2	36	theme	added-value	376:386	arg1	FM					409:410	FM	409:410	FM	409:410	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	1	37	theme	tremendous	212:221	arg1	amount					223:228	a tremendous amount	210:228	a tremendous amount of waste, the so-called sugarcane bagasse (SCB)	210:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	37	theme	tremendous	212:221	arg1	bagasse					264:270	the so-called sugarcane bagasse	240:270	the so-called sugarcane bagasse (SCB)	240:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	37	theme	tremendous	212:221	arg1	waste					233:237	waste	233:237	waste	233:237	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	0	38	theme	zero-waste	7:16	arg1	pathway					18:24	Green, zero-waste pathway	0:24	pathway	18:24	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	6	39	theme	liquid	935:940	arg1	waste					942:946	the residual liquid waste	922:946	the residual liquid waste	922:946	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	11	40	theme	trypanocidal	1441:1452	arg1	effects					1454:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	exceptional leishmanicidal and trypanocidal effects	1410:1460	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	12	41	theme	green	1625:1629	arg1	chemistry					1631:1639	green chemistry	1625:1639	green chemistry	1625:1639	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	6	42	theme	residual	926:933	arg1	waste					942:946	the residual liquid waste	922:946	the residual liquid waste	922:946	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	5	43	theme	copper	699:704	arg1	solution					687:694	a bimetallic solution	674:694	a bimetallic solution of copper and silver nitrates	674:724	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	10	44	theme	anti-kinetoplastid	1265:1282	arg1	materials					1284:1292	new anti-kinetoplastid materials	1261:1292	new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi	1261:1379	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	44	theme	anti-kinetoplastid	1265:1282	arg1	FM0					1229:1231	FM0	1229:1231	FM0	1229:1231	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	44	theme	anti-kinetoplastid	1265:1282	arg1	FM2					1242:1244	FM2	1242:1244	FM2	1242:1244	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	10	44	theme	anti-kinetoplastid	1265:1282	arg1	FM1					1234:1236	FM1	1234:1236	FM1	1234:1236	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	3	45	theme	novel	435:439	arg1	pathway					452:458	a novel zero-waste pathway	433:458	a novel zero-waste pathway to fabricate two FMs from one biomass	433:496	Herein, we propose a novel zero-waste pathway to fabricate two FMs from one biomass.					
36379167	8	46	theme	order	1114:1118	arg1	rate					1120:1123	the pseudo-second order rate	1096:1123	the pseudo-second order rate	1096:1123	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	47	theme	K2	1192:1193	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	47	theme	K2	1192:1193	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	12	48	theme	agrowaste	1645:1653	arg1	valorization					1655:1666	agrowaste valorization	1645:1666	agrowaste valorization	1645:1666	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	6	49	theme	intermediate	751:762	arg1	FM0					775:777	FM0	775:777	FM0	775:777	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	6	49	theme	intermediate	751:762	arg1	composite					764:772	an intermediate composite	748:772	an intermediate composite (FM0)	748:778	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	6	49	theme	intermediate	751:762	arg1	SCB					803:805	Ag/Cu-Ag+/Cu2+-loaded SCB	781:805	Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste	781:946	The process produced an intermediate composite (FM0), Ag/Cu-Ag+/Cu2+-loaded SCB which was carbonized to elaborate Ag/Cu-Biochar (FM1), free Ag/Cu nanoparticles (FM2) were obtained by microwaving the residual liquid waste.					
36379167	3	50	theme	zero-waste	441:450	arg1	pathway					452:458	a novel zero-waste pathway	433:458	a novel zero-waste pathway to fabricate two FMs from one biomass	433:496	Herein, we propose a novel zero-waste pathway to fabricate two FMs from one biomass.					
36379167	7	51	theme	blue	1038:1041	arg1	methylene					1028:1036	methylene blue	1028:1041	methylene blue	1028:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	8	52	theme	rate	1156:1159	arg1	min-1					1182:1186	K1 45 10-3 min-1	1171:1186	K1 45 10-3 min-1	1171:1186	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	52	theme	rate	1156:1159	arg1	0.115 g.mg-1					1195:1206	K2 0.115 g.mg-1	1192:1206	K2 0.115 g.mg-1	1192:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	8	52	theme	rate	1156:1159	arg1	constants					1161:1169	apparent degradation rate constants	1135:1169	apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1135:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	7	53	theme	total	995:999	arg1	degradation					1013:1023	the total Fenton-like degradation	991:1023	the total Fenton-like degradation of methylene blue	991:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	1	54	theme	conversion	121:130	arg1	processes					132:140	The conversion processes	117:140	The conversion processes of sugarcane into direct-consumption sugar and juice	117:193	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	7	55	theme	methylene	1028:1036	arg1	degradation					1013:1023	the total Fenton-like degradation	991:1023	the total Fenton-like degradation of methylene blue	991:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	7	56	theme	Fenton-like	1001:1011	arg1	degradation					1013:1023	the total Fenton-like degradation	991:1023	the total Fenton-like degradation of methylene blue	991:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	0	57	dep	pathway	18:24	arg1	fabricate					29:37	fabricate	29:37	to fabricate	26:37	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	10	58	theme	flagellated	1306:1316	arg1	protozoans					1318:1327	two flagellated protozoans	1302:1327	two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi	1302:1379	FM0, FM1 and FM2 were tested as new anti-kinetoplastid materials against two flagellated protozoans namely the Leishmania spp and the Trypanosoma cruzi.					
36379167	12	59	theme	full	1673:1676	arg1	process					1689:1695	a full zero-waste process	1671:1695	a full zero-waste process	1671:1695	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	11	60	theme	2.909 ± 0.051	1482:1494	arg1	values					1472:1477	IC50 values	1467:1477	IC50 values	1467:1477	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	5	61	theme	bimetallic	676:685	arg1	solution					687:694	a bimetallic solution	674:694	a bimetallic solution of copper and silver nitrates	674:724	Then, the H2O/EtOH-extracted SCB was in-situ impregnated with a bimetallic solution of copper and silver nitrates.					
36379167	0	62	from	bagasse	108:114	arg1	agents					86:91	anti-kinetoplastid agents	67:91	anti-kinetoplastid agents	67:91	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	0	62	from	bagasse	108:114	arg1	nanocatalysts					49:61	nanocatalysts	49:61	nanocatalysts	49:61	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	12	63	theme	development	1788:1798	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	63	theme	development	1788:1798	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	63	theme	development	1788:1798	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	7	64	theme	high	963:966	arg1	activity					978:985	high catalytic activity	963:985	high catalytic activity for the total Fenton-like degradation of methylene blue	963:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	1	65	theme	sugarcane	145:153	arg1	processes					132:140	The conversion processes	117:140	The conversion processes of sugarcane into direct-consumption sugar and juice	117:193	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	11	66	theme	IC50	1467:1470	arg1	values					1472:1477	IC50 values	1467:1477	IC50 values	1467:1477	Notably, Ag/Cu (FM2) showed exceptional leishmanicidal and trypanocidal effects with IC50 values of 2.909 ± 0.051, 3.580 ± 0.016 and 3.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively.					
36379167	0	67	theme	anti-kinetoplastid	67:84	arg1	agents					86:91	anti-kinetoplastid agents	67:91	anti-kinetoplastid agents	67:91	Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse.					
36379167	1	68	theme	waste	233:237	arg1	amount					223:228	a tremendous amount	210:228	a tremendous amount of waste, the so-called sugarcane bagasse (SCB)	210:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	68	theme	waste	233:237	arg1	bagasse					264:270	the so-called sugarcane bagasse	240:270	the so-called sugarcane bagasse (SCB)	240:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	68	theme	waste	233:237	arg1	waste					233:237	waste	233:237	waste	233:237	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	7	69	theme	catalytic	968:976	arg1	activity					978:985	high catalytic activity	963:985	high catalytic activity for the total Fenton-like degradation of methylene blue	963:1041	FM1 exhibited high catalytic activity for the total Fenton-like degradation of methylene blue.					
36379167	2	70	theme	high	371:374	arg1	material					399:406	high added-value functional material	371:406	high added-value functional material (FM)	371:411	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	2	70	theme	high	371:374	arg1	FM					409:410	FM	409:410	FM	409:410	Biochar preparation is among the practical solutions aiming to manage and valorize SCB into high added-value functional material (FM).					
36379167	1	71	theme	so-called	244:252	arg1	SCB					273:275	SCB	273:275	SCB	273:275	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	71	theme	so-called	244:252	arg1	bagasse					264:270	the so-called sugarcane bagasse	240:270	the so-called sugarcane bagasse (SCB)	240:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	71	theme	so-called	244:252	arg1	waste					233:237	waste	233:237	waste	233:237	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	8	72	theme	rate	1120:1123	arg1	laws					1125:1128	the pseudo-first and the pseudo-second order rate laws	1075:1128	the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1	1075:1206	The experimental data followed the pseudo-first and the pseudo-second order rate laws with apparent degradation rate constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.					
36379167	1	73	theme	sugarcane	254:262	arg1	SCB					273:275	SCB	273:275	SCB	273:275	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	73	theme	sugarcane	254:262	arg1	bagasse					264:270	the so-called sugarcane bagasse	240:270	the so-called sugarcane bagasse (SCB)	240:276	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	1	73	theme	sugarcane	254:262	arg1	waste					233:237	waste	233:237	waste	233:237	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	12	74	theme	Nations	1768:1774	arg1	Well-Being″					1824:1834	Well-Being″	1824:1834	Well-Being″	1824:1834	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	74	theme	Nations	1768:1774	arg1	goals					1800:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals	1709:1804	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	12	74	theme	Nations	1768:1774	arg1	Health					1813:1818	″Good Health	1807:1818	″Good Health	1807:1818	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	1	75	theme	direct-consumption	160:177	arg1	sugar					179:183	direct-consumption sugar	160:183	direct-consumption sugar	160:183	The conversion processes of sugarcane into direct-consumption sugar and juice are generating a tremendous amount of waste, the so-called sugarcane bagasse (SCB).					
36379167	12	76	theme	zero-waste	1678:1687	arg1	process					1689:1695	a full zero-waste process	1671:1695	a full zero-waste process	1671:1695	In this way, we combine green chemistry and agrowaste valorization in a full zero-waste process, to address the 3rd (indicator 3.3.5) and 6th (indicator 6.3.1) United Nations sustainable development goals, ″Good Health and Well-Being″ and ″Clean Water and Sanitation″.					
36379167	4	77	theme	bio-reducing	591:602	arg1	medium					604:609	bio-reducing medium	591:609	bio-reducing medium	591:609	The SCB was first macerated and ultrasonicated to obtain the natural extract that served as bio-reducing medium.					
35163962	0	0	theme	Wound	105:109	arg1	Healing					111:117	Wound Healing	105:117	Wound Healing	105:117	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	5	1	theme	cells	1083:1087	arg1	presence					1052:1059	the presence	1048:1059	the presence of HFB-4 and HSF skin cells	1048:1087	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	4	2	theme	phosphate	899:907	arg1	DCPDH					920:924	DCPDH	920:924	DCPDH	920:924	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	2	theme	phosphate	899:907	arg1	dehydrate					909:917	dicalcium phosphate dehydrate	889:917	dicalcium phosphate dehydrate (DCPDH)	889:925	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	6	3	theme	wound	1496:1500	arg1	healing					1502:1508	wound healing	1496:1508	wound healing	1496:1508	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	5	4	from	increase	1191:1198	arg1	viability					1208:1216	cell viability	1203:1216	cell viability	1203:1216	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	4	5	theme	mineralized	785:795	arg1	hydrogels					804:812	different mineralized hybrid hydrogels	775:812	different mineralized hybrid hydrogels	775:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	6	theme	dicalcium	889:897	arg1	DCPDH					920:924	DCPDH	920:924	DCPDH	920:924	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	6	theme	dicalcium	889:897	arg1	dehydrate					909:917	dicalcium phosphate dehydrate	889:917	dicalcium phosphate dehydrate (DCPDH)	889:925	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	5	7	theme	HFB-4	1064:1068	arg1	presence					1052:1059	the presence	1048:1059	the presence of HFB-4 and HSF skin cells	1048:1087	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	6	8	theme	promising	1413:1421	arg1	use					1423:1425	a promising use	1411:1425	a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications	1411:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	1	9	theme	damaged	309:315	arg1	areas					324:328	damaged tissue areas	309:328	damaged tissue areas	309:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	4	10	dep	pH	1007:1008	arg1	i.e.					1001:1004	i.e.	1001:1004	i.e.	1001:1004	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	11	theme	different	775:783	arg1	hydrogels					804:812	different mineralized hybrid hydrogels	775:812	different mineralized hybrid hydrogels	775:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	3	12	theme	chains	587:592	arg1	reaction					567:574	a crosslinking reaction	552:574	a crosslinking reaction of polymer chains	552:592	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	1	13	theme	tissue	317:322	arg1	areas					324:328	damaged tissue areas	309:328	damaged tissue areas	309:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	4	14	from	differences	826:836	arg1	nanostructures					867:880	the deposited crystalline nanostructures	841:880	the deposited crystalline nanostructures	841:880	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	3	15	theme	polymer	579:585	arg1	chains					587:592	polymer chains	579:592	polymer chains	579:592	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	5	16	dep	in	1029:1030	arg1	vitro					1032:1036	vitro	1032:1036	vitro	1032:1036	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	17	theme	hybrid	1314:1319	arg1	materials					1321:1329	Alg/PVA/calcium phosphate hybrid materials	1288:1329	Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL)	1288:1340	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	17	theme	hybrid	1314:1319	arg1	mg/mL					1335:1339	<1 mg/mL	1332:1339	<1 mg/mL	1332:1339	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	1	18	theme	areas	324:328	arg1	processes					296:304	healing/regeneration processes	275:304	healing/regeneration processes of damaged tissue areas	275:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	4	19	theme	applied	978:984	arg1	conditions					989:998	applied pH conditions	978:998	applied pH conditions (i.e., pH 4 or 8)	978:1016	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	20	theme	morphological	723:735	arg1	properties					761:770	the morphological, chemical, and physical properties	719:770	the morphological, chemical, and physical properties of different mineralized hybrid hydrogels	719:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	21	theme	hybrid	797:802	arg1	hydrogels					804:812	different mineralized hybrid hydrogels	775:812	different mineralized hybrid hydrogels	775:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	6	22	theme	hybrid	1442:1447	arg1	hydrogels					1449:1457	mineralized hybrid hydrogels	1430:1457	mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications	1430:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	2	23	theme	polyvinyl	427:435	arg1	PVA					446:448	PVA	446:448	PVA	446:448	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	23	theme	polyvinyl	427:435	arg1	alcohol					437:443	polyvinyl alcohol	427:443	polyvinyl alcohol (PVA)	427:449	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	24	theme	stable	470:475	arg1	hydrogel					489:496	a stable mineralized hydrogel	468:496	a stable mineralized hydrogel	468:496	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	25	dep	alginate	408:415	arg1	solution					451:458	solution	451:458	solution	451:458	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	5	26	theme	Alg/PVA/calcium	1288:1302	arg1	materials					1321:1329	Alg/PVA/calcium phosphate hybrid materials	1288:1329	Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL)	1288:1340	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	26	theme	Alg/PVA/calcium	1288:1302	arg1	mg/mL					1335:1339	<1 mg/mL	1332:1339	<1 mg/mL	1332:1339	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	3	27	dep	in	615:616	arg1	situ					618:621	situ	618:621	situ	618:621	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	0	28	theme	Polyvinyl	12:20	arg1	Hydrogels					46:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	5	29	theme	HSF	1074:1076	arg1	cells					1083:1087	HSF skin cells	1074:1087	HSF skin cells	1074:1087	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	2	30	from	embedded	396:403	arg1	PVA					446:448	PVA	446:448	PVA	446:448	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	30	from	embedded	396:403	arg1	Alg					418:420	Alg	418:420	Alg	418:420	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	30	from	embedded	396:403	arg1	work					339:342	this work	334:342	this work	334:342	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	30	from	embedded	396:403	arg1	alginate					408:415	alginate	408:415	alginate (Alg)	408:421	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	30	from	embedded	396:403	arg1	alcohol					437:443	polyvinyl alcohol	427:443	polyvinyl alcohol (PVA)	427:449	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	5	31	theme	phosphate	1304:1312	arg1	materials					1321:1329	Alg/PVA/calcium phosphate hybrid materials	1288:1329	Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL)	1288:1340	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	31	theme	phosphate	1304:1312	arg1	mg/mL					1335:1339	<1 mg/mL	1332:1339	<1 mg/mL	1332:1339	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	1	32	theme	valid	217:221	arg1	strategy					223:230	a valid strategy	215:230	a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas	215:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	0	33	theme	Mineralized	0:10	arg1	Hydrogels					46:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	6	34	theme	hydrogels	1449:1457	arg1	use					1423:1425	a promising use	1411:1425	a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications	1411:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	5	35	theme	hydroxyapatite	1361:1374	arg1	presence					1349:1356	the presence	1345:1356	the presence of hydroxyapatite	1345:1374	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	2	36	theme	cellulose	360:368	arg1	T-CNFs					383:388	T-CNFs	383:388	T-CNFs	383:388	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	36	theme	cellulose	360:368	arg1	nanofibrils					370:380	TEMPO-oxidized cellulose nanofibrils	345:380	TEMPO-oxidized cellulose nanofibrils (T-CNFs)	345:389	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	6	37	theme	bone	1487:1490	arg1	applications					1510:1521	bone and wound healing applications	1487:1521	bone and wound healing applications	1487:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	0	38	theme	Alginate	37:44	arg1	Hydrogels					46:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	5	39	theme	mineralized	1126:1136	arg1	hydrogels					1145:1153	the mineralized hybrid hydrogels	1122:1153	the mineralized hybrid hydrogels	1122:1153	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	40	attach	crosslinked	1276:1286	arg3	presence					1349:1356	the presence	1345:1356	the presence of hydroxyapatite	1345:1374	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	2	41	from	alginate	408:415	arg1	embedded					396:403	embedded	396:403	embedded	396:403	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	1	42	theme	Bio	120:122	arg1	hydrogels					136:144	Bio sustainable hydrogels	120:144	Bio sustainable hydrogels including tunable morphological and/or chemical cues	120:197	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	0	43	theme	Alcohol/Sodium	22:35	arg1	Hydrogels					46:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels	0:54	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	5	44	theme	hybrid	1138:1143	arg1	hydrogels					1145:1153	the mineralized hybrid hydrogels	1122:1153	the mineralized hybrid hydrogels	1122:1153	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	1	45	theme	sustainable	124:134	arg1	hydrogels					136:144	Bio sustainable hydrogels	120:144	Bio sustainable hydrogels including tunable morphological and/or chemical cues	120:197	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	5	46	theme	low	1257:1259	arg1	concentration					1261:1273	the low concentration	1253:1273	the low concentration	1253:1273	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	1	47	theme	designing	235:243	arg1	systems					256:262	designing innovative systems	235:262	designing innovative systems	235:262	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	5	48	theme	hydrogels	1145:1153	arg1	cytotoxicity					1106:1117	a low cytotoxicity	1100:1117	a low cytotoxicity of the mineralized hybrid hydrogels	1100:1153	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	6	49	theme	mineralized	1430:1440	arg1	hydrogels					1449:1457	mineralized hybrid hydrogels	1430:1457	mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications	1430:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	1	50	theme	innovative	245:254	arg1	systems					256:262	designing innovative systems	235:262	designing innovative systems	235:262	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	4	51	dep	dehydrate	909:917	arg1	i.e.					883:886	i.e.	883:886	i.e.	883:886	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	6	52	theme	preliminary	1383:1393	arg1	results					1395:1401	These preliminary results	1377:1401	These preliminary results	1377:1401	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	1	53	theme	systems	256:262	arg1	strategy					223:230	a valid strategy	215:230	a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas	215:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	2	54	theme	mineralized	477:487	arg1	hydrogel					489:496	a stable mineralized hydrogel	468:496	a stable mineralized hydrogel	468:496	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	5	55	theme	low	1102:1104	arg1	cytotoxicity					1106:1117	a low cytotoxicity	1100:1117	a low cytotoxicity of the mineralized hybrid hydrogels	1100:1153	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	4	56	theme	deposited	845:853	arg1	nanostructures					867:880	the deposited crystalline nanostructures	841:880	the deposited crystalline nanostructures	841:880	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	5	57	from	tests	1038:1042	arg1	presence					1052:1059	the presence	1048:1059	the presence of HFB-4 and HSF skin cells	1048:1087	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	4	58	theme	crystalline	855:865	arg1	nanostructures					867:880	the deposited crystalline nanostructures	841:880	the deposited crystalline nanostructures	841:880	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	3	59	theme	chloride	509:516	arg1	reaction					518:525	A calcium chloride reaction	499:525	A calcium chloride reaction	499:525	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	0	60	theme	Cellulose	70:78	arg1	Nanofibrils					80:90	Cellulose Nanofibrils	70:90	Cellulose Nanofibrils	70:90	Mineralized Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporating Cellulose Nanofibrils for Bone and Wound Healing.					
35163962	3	61	theme	in	615:616	arg1	mineralization					623:636	in situ mineralization	615:636	in situ mineralization of calcium phosphates	615:658	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	5	62	theme	significant	1179:1189	arg1	increase					1191:1198	a significant increase	1177:1198	a significant increase in cell viability	1177:1216	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	5	63	theme	in	1029:1030	arg1	tests					1038:1042	in vitro tests	1029:1042	in vitro tests	1029:1042	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	3	64	theme	phosphates	649:658	arg1	mineralization					623:636	in situ mineralization	615:636	in situ mineralization of calcium phosphates	615:658	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	1	65	theme	tunable	156:162	arg1	cues					194:197	tunable morphological and/or chemical cues	156:197	tunable morphological and/or chemical cues	156:197	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	2	66	theme	TEMPO-oxidized	345:358	arg1	T-CNFs					383:388	T-CNFs	383:388	T-CNFs	383:388	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	2	66	theme	TEMPO-oxidized	345:358	arg1	nanofibrils					370:380	TEMPO-oxidized cellulose nanofibrils	345:380	TEMPO-oxidized cellulose nanofibrils (T-CNFs)	345:389	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	3	67	theme	crosslinking	554:565	arg1	reaction					567:574	a crosslinking reaction	552:574	a crosslinking reaction of polymer chains	552:592	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	6	68	theme	healing	1502:1508	arg1	applications					1510:1521	bone and wound healing applications	1487:1521	bone and wound healing applications	1487:1521	These preliminary results suggest a promising use of mineralized hybrid hydrogels based on Alg/PVA/T-CNFs for bone and wound healing applications.					
35163962	4	69	theme	hydrogels	804:812	arg1	properties					761:770	the morphological, chemical, and physical properties	719:770	the morphological, chemical, and physical properties of different mineralized hybrid hydrogels	719:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	70	theme	physical	752:759	arg1	properties					761:770	the morphological, chemical, and physical properties	719:770	the morphological, chemical, and physical properties of different mineralized hybrid hydrogels	719:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	1	71	theme	morphological	164:176	arg1	cues					194:197	tunable morphological and/or chemical cues	156:197	tunable morphological and/or chemical cues	156:197	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	2	72	from	work	339:342	arg1	embedded					396:403	embedded	396:403	embedded	396:403	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	4	73	theme	chemical	738:745	arg1	properties					761:770	the morphological, chemical, and physical properties	719:770	the morphological, chemical, and physical properties of different mineralized hybrid hydrogels	719:812	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	74	theme	conditions	989:998	arg1	differences					826:836	differences	826:836	differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively,	826:959	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	4	74	theme	conditions	989:998	arg1	function					966:973	a function	964:973	a function of applied pH conditions (i.e., pH 4 or 8)	964:1016	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	5	75	theme	MTT	1222:1224	arg1	tests					1226:1230	MTT tests	1222:1230	MTT tests	1222:1230	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	2	76	from	alcohol	437:443	arg1	embedded					396:403	embedded	396:403	embedded	396:403	In this work, TEMPO-oxidized cellulose nanofibrils (T-CNFs) were embedded in alginate (Alg) and polyvinyl alcohol (PVA) solution to form a stable mineralized hydrogel.					
35163962	3	77	theme	calcium	501:507	arg1	reaction					518:525	A calcium chloride reaction	499:525	A calcium chloride reaction	499:525	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	1	78	theme	healing/regeneration	275:294	arg1	processes					296:304	healing/regeneration processes	275:304	healing/regeneration processes of damaged tissue areas	275:328	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	4	79	theme	pH	986:987	arg1	conditions					989:998	applied pH conditions	978:998	applied pH conditions (i.e., pH 4 or 8)	978:1016	FTIR, XRD, SEM/EDAX, and TEM were assessed to investigate the morphological, chemical, and physical properties of different mineralized hybrid hydrogels, confirming differences in the deposited crystalline nanostructures, i.e., dicalcium phosphate dehydrate (DCPDH) and hydroxyapatite, respectively, as a function of applied pH conditions (i.e., pH 4 or 8).					
35163962	5	80	theme	skin	1078:1081	arg1	cells					1083:1087	HSF skin cells	1074:1087	HSF skin cells	1074:1087	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35163962	3	81	theme	calcium	641:647	arg1	phosphates					649:658	calcium phosphates	641:658	calcium phosphates	641:658	A calcium chloride reaction was optimized to trigger a crosslinking reaction of polymer chains and mutually promote in situ mineralization of calcium phosphates.					
35163962	1	82	theme	chemical	185:192	arg1	cues					194:197	tunable morphological and/or chemical cues	156:197	tunable morphological and/or chemical cues	156:197	Bio sustainable hydrogels including tunable morphological and/or chemical cues currently offer a valid strategy of designing innovative systems to enhance healing/regeneration processes of damaged tissue areas.					
35163962	5	83	theme	cell	1203:1206	arg1	viability					1208:1216	cell viability	1203:1216	cell viability	1203:1216	Moreover, in vitro tests, in the presence of HFB-4 and HSF skin cells, confirmed a low cytotoxicity of the mineralized hybrid hydrogels, and also highlighted a significant increase in cell viability via MTT tests, preferentially, for the low concentration, crosslinked Alg/PVA/calcium phosphate hybrid materials (<1 mg/mL) in the presence of hydroxyapatite.					
35287915	3	0	theme	crucial	400:406	arg1	adhesiveness					366:377	adhesiveness	366:377	adhesiveness	366:377	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	3	0	theme	crucial	400:406	arg1	challenges					408:417	crucial challenges	400:417	crucial challenges for tissue engineering applications	400:453	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	3	0	theme	crucial	400:406	arg1	injectability					348:360	injectability	348:360	injectability	348:360	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	4	1	theme	rapid	598:602	arg1	regeneration					609:620	rapid skin regeneration	598:620	rapid skin regeneration	598:620	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	5	2	theme	improved	642:649	arg1	activity					660:667	improved cellular activity	642:667	improved cellular activity	642:667	The s-NC exhibited improved cellular activity than cellulose nanocrystals.					
35287915	1	3	theme	physicochemical	202:216	arg1	properties					218:227	their superior physicochemical properties	187:227	their superior physicochemical properties	187:227	Cellulose nanomaterials have received significant interest due to their superior physicochemical properties and biocompatibility.					
35287915	10	4	theme	regeneration	1214:1225	arg1	applications					1227:1238	enhanced skin regeneration applications	1200:1238	enhanced skin regeneration applications	1200:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	4	5	theme	spherical	529:537	arg1	chitosan					585:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	10	6	theme	skin	1209:1212	arg1	applications					1227:1238	enhanced skin regeneration applications	1200:1238	enhanced skin regeneration applications	1200:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	7	7	theme	added	853:857	arg1	hydrogels					859:867	s-NC added hydrogels	848:867	s-NC added hydrogels than the pure polymer hydrogel	848:898	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	4	8	theme	carboxymethyl	571:583	arg1	chitosan					585:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	8	9	theme	healing	1005:1011	arg1	model					1013:1017	the wound healing model	995:1017	the wound healing model	995:1017	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	8	10	theme	hydrogel	940:947	arg1	scaffolds					949:957	the hydrogel scaffolds	936:957	the hydrogel scaffolds	936:957	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	3	11	theme	engineering	430:440	arg1	applications					442:453	tissue engineering applications	423:453	tissue engineering applications	423:453	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	4	12	theme	reinforced	560:569	arg1	chitosan					585:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan	529:592	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	4	13	theme	injectable	493:502	arg1	hydrogel					517:524	an injectable and adhesive hydrogel	490:524	an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration	490:620	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	8	14	theme	wound	999:1003	arg1	healing					1005:1011	the wound healing	995:1011	the wound healing model	995:1017	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	0	15	theme	chitosan/spherical	15:32	arg1	hydrogel					54:61	chitosan/spherical nanocellulose-based hydrogel	15:61	chitosan/spherical nanocellulose-based hydrogel	15:61	Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing.					
35287915	4	16	theme	chitosan	585:592	arg1	hydrogel					517:524	an injectable and adhesive hydrogel	490:524	an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration	490:620	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	1	17	theme	Cellulose	121:129	arg1	nanomaterials					131:143	Cellulose nanomaterials	121:143	Cellulose nanomaterials	121:143	Cellulose nanomaterials have received significant interest due to their superior physicochemical properties and biocompatibility.					
35287915	10	18	theme	promising	1174:1182	arg1	hydrogels					1120:1128	the developed hydrogels	1106:1128	the developed hydrogels	1106:1128	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	10	18	theme	promising	1174:1182	arg1	biomaterial					1184:1194	a promising biomaterial	1172:1194	a promising biomaterial for enhanced skin regeneration applications	1172:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	7	19	dep	added	853:857	arg1	s-NC					848:851	s-NC	848:851	s-NC	848:851	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	6	20	theme	adhesive	722:729	arg1	potentials					749:758	adhesive and injectability potentials	722:758	adhesive and injectability potentials	722:758	The hydrogels exhibited adhesive and injectability potentials and were molded in the desired configurations.					
35287915	9	21	theme	antibacterial	1065:1077	arg1	potential					1079:1087	improved antibacterial potential	1056:1087	improved antibacterial potential	1056:1087	The composite scaffolds also showed improved antibacterial potential.					
35287915	0	22	theme	nanocellulose-based	34:52	arg1	hydrogel					54:61	chitosan/spherical nanocellulose-based hydrogel	15:61	chitosan/spherical nanocellulose-based hydrogel	15:61	Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing.					
35287915	0	23	theme	superior	68:75	arg1	efficiency					91:100	superior antibacterial efficiency	68:100	superior antibacterial efficiency for wound healing	68:118	Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing.					
35287915	2	24	theme	skin	316:319	arg1	regeneration					321:332	skin regeneration	316:332	skin regeneration	316:332	The nanomaterials-based hydrogel patches are widely explored for skin regeneration.					
35287915	7	25	located	observed	836:843	arg2	conductivity					819:830	An enhanced conductivity	807:830	An enhanced conductivity	807:830	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	7	25	located	observed	836:843	arg1	hydrogels					859:867	s-NC added hydrogels	848:867	s-NC added hydrogels than the pure polymer hydrogel	848:898	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	5	26	theme	cellular	651:658	arg1	activity					660:667	improved cellular activity	642:667	improved cellular activity	642:667	The s-NC exhibited improved cellular activity than cellulose nanocrystals.					
35287915	3	27	theme	hydrogels	386:394	arg1	adhesiveness					366:377	adhesiveness	366:377	adhesiveness	366:377	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	3	27	theme	hydrogels	386:394	arg1	injectability					348:360	injectability	348:360	injectability	348:360	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	3	27	theme	hydrogels	386:394	arg1	challenges					408:417	crucial challenges	400:417	crucial challenges for tissue engineering applications	400:453	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	9	28	theme	improved	1056:1063	arg1	potential					1079:1087	improved antibacterial potential	1056:1087	improved antibacterial potential	1056:1087	The composite scaffolds also showed improved antibacterial potential.					
35287915	10	29	theme	developed	1110:1118	arg1	hydrogels					1120:1128	the developed hydrogels	1106:1128	the developed hydrogels	1106:1128	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	10	29	theme	developed	1110:1118	arg1	biomaterial					1184:1194	a promising biomaterial	1172:1194	a promising biomaterial for enhanced skin regeneration applications	1172:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	10	30	contain	have	1130:1133	arg1	hydrogels					1120:1128	the developed hydrogels	1106:1128	the developed hydrogels	1106:1128	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	10	30	contain	have	1130:1133	arg1	biomaterial					1184:1194	a promising biomaterial	1172:1194	a promising biomaterial for enhanced skin regeneration applications	1172:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	10	30	contain	have	1130:1133	arg2	potential					1139:1147	the potential	1135:1147	the potential	1135:1147	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	1	31	theme	significant	159:169	arg1	interest					171:178	significant interest	159:178	significant interest	159:178	Cellulose nanomaterials have received significant interest due to their superior physicochemical properties and biocompatibility.					
35287915	0	32	theme	antibacterial	77:89	arg1	efficiency					91:100	superior antibacterial efficiency	68:100	superior antibacterial efficiency for wound healing	68:118	Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing.					
35287915	9	33	theme	composite	1024:1032	arg1	scaffolds					1034:1042	The composite scaffolds	1020:1042	The composite scaffolds	1020:1042	The composite scaffolds also showed improved antibacterial potential.					
35287915	7	34	theme	enhanced	810:817	arg1	conductivity					819:830	An enhanced conductivity	807:830	An enhanced conductivity	807:830	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	8	35	theme	scaffolds	949:957	arg1	potential					923:931	The skin regeneration potential	901:931	The skin regeneration potential of the hydrogel scaffolds	901:957	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	4	36	theme	adhesive	508:515	arg1	hydrogel					517:524	an injectable and adhesive hydrogel	490:524	an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration	490:620	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	5	37	theme	cellulose	674:682	arg1	nanocrystals					684:695	cellulose nanocrystals	674:695	cellulose nanocrystals	674:695	The s-NC exhibited improved cellular activity than cellulose nanocrystals.					
35287915	6	38	theme	desired	783:789	arg1	configurations					791:804	the desired configurations	779:804	the desired configurations	779:804	The hydrogels exhibited adhesive and injectability potentials and were molded in the desired configurations.					
35287915	8	39	theme	skin	905:908	arg1	potential					923:931	The skin regeneration potential	901:931	The skin regeneration potential of the hydrogel scaffolds	901:957	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	2	40	theme	hydrogel	275:282	arg1	patches					284:290	The nanomaterials-based hydrogel patches	251:290	The nanomaterials-based hydrogel patches	251:290	The nanomaterials-based hydrogel patches are widely explored for skin regeneration.					
35287915	0	41	theme	wound	106:110	arg1	healing					112:118	wound healing	106:118	wound healing	106:118	Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing.					
35287915	2	42	theme	nanomaterials-based	255:273	arg1	patches					284:290	The nanomaterials-based hydrogel patches	251:290	The nanomaterials-based hydrogel patches	251:290	The nanomaterials-based hydrogel patches are widely explored for skin regeneration.					
35287915	6	43	theme	injectability	735:747	arg1	potentials					749:758	adhesive and injectability potentials	722:758	adhesive and injectability potentials	722:758	The hydrogels exhibited adhesive and injectability potentials and were molded in the desired configurations.					
35287915	7	44	theme	pure	878:881	arg1	hydrogel					891:898	the pure polymer hydrogel	874:898	the pure polymer hydrogel	874:898	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35287915	3	45	theme	tissue	423:428	arg1	applications					442:453	tissue engineering applications	423:453	tissue engineering applications	423:453	However, the injectability and adhesiveness of the hydrogels are crucial challenges for tissue engineering applications.					
35287915	4	46	theme	skin	604:607	arg1	regeneration					609:620	rapid skin regeneration	598:620	rapid skin regeneration	598:620	To overcome these, we synthesized an injectable and adhesive hydrogel of spherical nanocellulose (s-NC) reinforced carboxymethyl chitosan for rapid skin regeneration.					
35287915	8	47	theme	regeneration	910:921	arg1	potential					923:931	The skin regeneration potential	901:931	The skin regeneration potential of the hydrogel scaffolds	901:957	The skin regeneration potential of the hydrogel scaffolds was also examined in the rats using the wound healing model.					
35287915	10	48	theme	enhanced	1200:1207	arg1	applications					1227:1238	enhanced skin regeneration applications	1200:1238	enhanced skin regeneration applications	1200:1238	Taken together, the developed hydrogels have the potential and can be explored as a promising biomaterial for enhanced skin regeneration applications.					
35287915	1	49	theme	superior	193:200	arg1	properties					218:227	their superior physicochemical properties	187:227	their superior physicochemical properties	187:227	Cellulose nanomaterials have received significant interest due to their superior physicochemical properties and biocompatibility.					
35287915	7	50	theme	polymer	883:889	arg1	hydrogel					891:898	the pure polymer hydrogel	874:898	the pure polymer hydrogel	874:898	An enhanced conductivity was observed in s-NC added hydrogels than the pure polymer hydrogel.					
35654221	0	0	theme	aronia	99:104	arg1	extract					106:112	aronia extract	99:112	aronia extract	99:112	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	2	1	theme	phenolic	487:494	arg1	content					496:502	total phenolic content	481:502	total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract	481:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	8	2	theme	shelf	1578:1582	arg1	life					1584:1587	shelf life	1578:1587	shelf life	1578:1587	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	8	3	theme	food	1601:1604	arg1	quality					1606:1612	food quality	1601:1612	food quality	1601:1612	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	2	4	theme	total	481:485	arg1	content					496:502	total phenolic content	481:502	total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract	481:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	1	5	theme	multifunctional	315:329	arg1	films					377:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films	315:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	315:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	5	6	theme	PVA/CS-A	870:877	arg1	film					906:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	2	7	theme	297 ± 0.5 μg	507:518	arg1	extract					534:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	2	8	theme	extract	534:540	arg1	content					496:502	total phenolic content	481:502	total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract	481:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	2	8	theme	extract	534:540	arg1	efficiency					596:605	high color-response efficiency	576:605	high color-response efficiency	576:605	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	2	8	theme	extract	534:540	arg1	activity					562:569	potent antioxidant activity	543:569	potent antioxidant activity	543:569	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	1	9	theme	polyvinyl	331:339	arg1	films					377:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films	315:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	315:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	0	10	with	films	88:92	arg1	extract					106:112	aronia extract	99:112	aronia extract	99:112	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	5	11	theme	significant	920:930	arg1	change					938:943	a significant color change	918:943	a significant color change	918:943	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	0	12	with	extract	159:165	arg1	extract					106:112	aronia extract	99:112	aronia extract	99:112	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	1	13	theme	grapefruit	252:261	arg1	GSE					277:279	GSE	277:279	GSE	277:279	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	13	theme	grapefruit	252:261	arg1	extract					268:274	grapefruit seed extract	252:274	grapefruit seed extract (GSE)	252:280	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	2	14	theme	aronia	527:532	arg1	extract					534:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	1	15	theme	alcohol/chitosan	341:356	arg1	films					377:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films	315:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	315:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	6	16	theme	monocytogenes	1128:1140	arg1	bacteria					1158:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	1	17	theme	UV-barrier	436:445	arg1	properties					447:456	UV-barrier properties	436:456	UV-barrier properties	436:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	5	18	theme	color	932:936	arg1	change					938:943	a significant color change	918:943	a significant color change	918:943	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	8	19	theme	active	1524:1529	arg1	films					1562:1566	active and intelligent food packaging films	1524:1566	active and intelligent food packaging films	1524:1566	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	1	20	theme	seed	263:266	arg1	GSE					277:279	GSE	277:279	GSE	277:279	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	20	theme	seed	263:266	arg1	extract					268:274	grapefruit seed extract	252:274	grapefruit seed extract (GSE)	252:280	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	2	21	theme	GAE/mg	520:525	arg1	extract					534:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	297 ± 0.5 μg GAE/mg aronia extract	507:540	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	6	22	theme	Listeria	1119:1126	arg1	bacteria					1158:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	1	23	theme	black	178:182	arg1	chokeberry					184:193	black chokeberry	178:193	black chokeberry	178:193	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	0	24	theme	cellulose	115:123	arg1	nanocrystals					125:136	cellulose nanocrystals	115:136	cellulose nanocrystals	115:136	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	1	25	theme	PVA/CS	359:364	arg1	films					377:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films	315:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	315:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	0	26	with	nanocrystals	125:136	arg1	extract					106:112	aronia extract	99:112	aronia extract	99:112	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	5	27	theme	composite	896:904	arg1	film					906:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	6	28	dep	coli	1094:1097	arg1	Gram-negative					1100:1112	Gram-negative	1100:1112	Gram-negative	1100:1112	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	3	29	with	structure	643:651	arg1	length					660:665	a length	658:665	a length of 470 nm	658:675	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	3	29	with	structure	643:651	arg1	width					683:687	a width	681:687	a width of 35 nm	681:696	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	7	30	theme	PVA/CS-CGA	1172:1181	arg1	film					1193:1196	The PVA/CS-CGA composite film	1168:1196	The PVA/CS-CGA composite film	1168:1196	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	4	31	theme	composite	734:742	arg1	film					744:747	the PVA/CS composite film	723:747	the PVA/CS composite film	723:747	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	1	32	used	used	287:290	arg2	extract					268:274	grapefruit seed extract	252:274	grapefruit seed extract (GSE)	252:280	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	GSE					277:279	GSE	277:279	GSE	277:279	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	chokeberry					184:193	black chokeberry	178:193	black chokeberry	178:193	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	nanocrystals					227:238	cellulose nanocrystals	217:238	cellulose nanocrystals (CNCs)	217:245	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	Aronia					168:173	Aronia	168:173	Aronia	168:173	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	melanocarpa					203:213	Aronia melanocarpa	196:213	Aronia melanocarpa	196:213	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	32	used	used	287:290	arg2	CNCs					241:244	CNCs	241:244	CNCs	241:244	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	8	33	theme	films	1495:1499	arg1	properties					1458:1467	The multifunctional properties	1438:1467	The multifunctional properties of the produced composite films	1438:1499	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	7	34	theme	mechanical	1415:1424	arg1	properties					1426:1435	desirable mechanical properties	1405:1435	desirable mechanical properties	1405:1435	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	4	35	theme	PVA/CS	727:732	arg1	film					744:747	the PVA/CS composite film	723:747	the PVA/CS composite film	723:747	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	7	36	theme	highest	1251:1257	arg1	UV-barrier					1259:1268	the highest UV-barrier	1247:1268	the highest UV-barrier (95.5%)	1247:1276	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	36	theme	highest	1251:1257	arg1	%					1275:1275	95.5%	1271:1275	95.5%	1271:1275	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	1	37	theme	Aronia	196:201	arg1	Aronia					168:173	Aronia	168:173	Aronia	168:173	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	37	theme	Aronia	196:201	arg1	melanocarpa					203:213	Aronia melanocarpa	196:213	Aronia melanocarpa	196:213	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	2	38	theme	potent	543:548	arg1	activity					562:569	potent antioxidant activity	543:569	potent antioxidant activity	543:569	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	7	39	theme	antioxidant	1287:1297	arg1	activity					1299:1306	highest antioxidant activity	1279:1306	highest antioxidant activity (95%)	1279:1312	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	39	theme	antioxidant	1287:1297	arg1	%					1311:1311	95%	1309:1311	95%	1309:1311	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	40	theme	antimicrobial	1322:1334	arg1	activity					1336:1343	potent antimicrobial activity	1315:1343	potent antimicrobial activity	1315:1343	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	5	41	theme	antioxidant	973:983	arg1	activity					985:992	potent antioxidant activity	966:992	potent antioxidant activity	966:992	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	2	42	theme	antioxidant	550:560	arg1	activity					562:569	potent antioxidant activity	543:569	potent antioxidant activity	543:569	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	1	43	theme	composite	367:375	arg1	films					377:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films	315:381	multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	315:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	4	44	theme	film	744:747	arg1	strength					711:718	The tensile strength	699:718	The tensile strength of the PVA/CS composite film	699:747	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	0	45	theme	pH-sensitive	32:43	arg1	polyvinyl					45:53	pH-sensitive polyvinyl	32:53	pH-sensitive polyvinyl	32:53	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	5	46	theme	aronia	880:885	arg1	film					906:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	0	47	theme	seed	154:157	arg1	extract					159:165	grapefruit seed extract	143:165	grapefruit seed extract	143:165	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	1	48	theme	films	377:381	arg1	preparation					300:310	the preparation	296:310	the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties	296:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	3	49	theme	Isolated	608:615	arg1	CNCs					617:620	Isolated CNCs	608:620	Isolated CNCs	608:620	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	1	50	with	films	377:381	arg1	properties					447:456	UV-barrier properties	436:456	UV-barrier properties	436:456	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	50	with	films	377:381	arg1	antimicrobial					404:416	antimicrobial	404:416	antimicrobial	404:416	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	50	with	films	377:381	arg1	pH-sensitivity					388:401	pH-sensitivity	388:401	pH-sensitivity	388:401	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	50	with	films	377:381	arg1	antioxidant					419:429	antioxidant	419:429	antioxidant	419:429	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	6	51	theme	same	1002:1005	arg1	time					1007:1010	the same time	998:1010	the same time	998:1010	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	0	52	theme	grapefruit	143:152	arg1	extract					159:165	grapefruit seed extract	143:165	grapefruit seed extract	143:165	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	7	53	theme	potent	1315:1320	arg1	activity					1336:1343	potent antimicrobial activity	1315:1343	potent antimicrobial activity	1315:1343	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	1	54	theme	cellulose	217:225	arg1	CNCs					241:244	CNCs	241:244	CNCs	241:244	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	1	54	theme	cellulose	217:225	arg1	nanocrystals					227:238	cellulose nanocrystals	217:238	cellulose nanocrystals (CNCs)	217:245	Aronia or black chokeberry (Aronia melanocarpa), cellulose nanocrystals (CNCs), and grapefruit seed extract (GSE) were used for the preparation of multifunctional polyvinyl alcohol/chitosan (PVA/CS) composite films with pH-sensitivity, antimicrobial, antioxidant, and UV-barrier properties.					
35654221	2	55	theme	Aronia	459:464	arg1	extract					466:472	Aronia extract	459:472	Aronia extract	459:472	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	2	56	theme	color-response	581:594	arg1	efficiency					596:605	high color-response efficiency	576:605	high color-response efficiency	576:605	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	8	57	theme	composite	1485:1493	arg1	films					1495:1499	the produced composite films	1472:1499	the produced composite films	1472:1499	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	4	58	theme	film	811:814	arg1	flexibility					816:826	the film flexibility	807:826	the film flexibility	807:826	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	8	59	theme	produced	1476:1483	arg1	films					1495:1499	the produced composite films	1472:1499	the produced composite films	1472:1499	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	4	60	dep	increased	749:757	arg1	whereas					799:805	whereas	799:805	whereas	799:805	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	3	61	theme	35 nm	692:696	arg1	length					660:665	a length	658:665	a length of 470 nm	658:675	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	3	61	theme	35 nm	692:696	arg1	width					683:687	a width	681:687	a width of 35 nm	681:696	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	2	62	theme	high	576:579	arg1	efficiency					596:605	high color-response efficiency	576:605	high color-response efficiency	576:605	Aronia extract showed total phenolic content of 297 ± 0.5 μg GAE/mg aronia extract, potent antioxidant activity, and high color-response efficiency.					
35654221	4	63	theme	tensile	703:709	arg1	strength					711:718	The tensile strength	699:718	The tensile strength of the PVA/CS composite film	699:747	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	6	64	theme	Gram-positive	1143:1155	arg1	bacteria					1158:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	Listeria monocytogenes (Gram-positive) bacteria	1119:1165	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	5	65	theme	different	948:956	arg1	pHs					958:960	different pHs	948:960	different pHs	948:960	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	3	66	theme	needle-like	631:641	arg1	structure					643:651	a needle-like structure	629:651	a needle-like structure with a length of 470 nm and a width of 35 nm	629:696	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	5	67	theme	extract	887:893	arg1	film					906:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film	866:909	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	8	68	theme	food	1547:1550	arg1	films					1562:1566	active and intelligent food packaging films	1524:1566	active and intelligent food packaging films	1524:1566	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	7	69	theme	lowest	1362:1367	arg1	WVP					1395:1397	WVP	1395:1397	WVP	1395:1397	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	69	theme	lowest	1362:1367	arg1	permeability					1381:1392	lowest water vapor permeability	1362:1392	lowest water vapor permeability (WVP)	1362:1398	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	3	70	theme	470 nm	670:675	arg1	length					660:665	a length	658:665	a length of 470 nm	658:675	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	3	70	theme	470 nm	670:675	arg1	width					683:687	a width	681:687	a width of 35 nm	681:696	Isolated CNCs showed a needle-like structure with a length of 470 nm and a width of 35 nm.					
35654221	7	71	theme	water	1369:1373	arg1	WVP					1395:1397	WVP	1395:1397	WVP	1395:1397	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	71	theme	water	1369:1373	arg1	permeability					1381:1392	lowest water vapor permeability	1362:1392	lowest water vapor permeability (WVP)	1362:1398	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	6	72	theme	antimicrobial	1051:1063	arg1	activity					1065:1072	the highest antimicrobial activity	1039:1072	the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria	1039:1165	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	8	73	theme	intelligent	1535:1545	arg1	films					1562:1566	active and intelligent food packaging films	1524:1566	active and intelligent food packaging films	1524:1566	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	7	74	theme	composite	1183:1191	arg1	film					1193:1196	The PVA/CS-CGA composite film	1168:1196	The PVA/CS-CGA composite film	1168:1196	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	75	theme	vapor	1375:1379	arg1	WVP					1395:1397	WVP	1395:1397	WVP	1395:1397	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	75	theme	vapor	1375:1379	arg1	permeability					1381:1392	lowest water vapor permeability	1362:1392	lowest water vapor permeability (WVP)	1362:1398	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	4	76	theme	CNCs	793:796	arg1	incorporation					776:788	the incorporation	772:788	the incorporation of CNCs	772:796	The tensile strength of the PVA/CS composite film increased by 74% after the incorporation of CNCs, whereas the film flexibility was enhanced by 75% after adding GSE.					
35654221	6	77	theme	highest	1043:1049	arg1	activity					1065:1072	the highest antimicrobial activity	1039:1072	the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria	1039:1165	At the same time, the PVA/CS-G (GSE) showed the highest antimicrobial activity against Escherichia coli (Gram-negative) and Listeria monocytogenes (Gram-positive) bacteria.					
35654221	7	78	theme	highest	1279:1285	arg1	activity					1299:1306	highest antioxidant activity	1279:1306	highest antioxidant activity (95%)	1279:1312	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	7	78	theme	highest	1279:1285	arg1	%					1311:1311	95%	1309:1311	95%	1309:1311	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	0	79	theme	composite	78:86	arg1	films					88:92	composite films	78:92	composite films with aronia extract	78:112	Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract.					
35654221	7	80	theme	desirable	1405:1413	arg1	properties					1426:1435	desirable mechanical properties	1405:1435	desirable mechanical properties	1405:1435	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	5	81	theme	potent	966:971	arg1	activity					985:992	potent antioxidant activity	966:992	potent antioxidant activity	966:992	The PVA/CS-A (aronia extract) composite film showed a significant color change at different pHs and potent antioxidant activity.					
35654221	7	82	theme	CNCs/GSE/Aronia	1215:1229	arg1	extract					1231:1237	CNCs/GSE/Aronia extract	1215:1237	CNCs/GSE/Aronia extract	1215:1237	The PVA/CS-CGA composite film, reinforced with CNCs/GSE/Aronia extract, showed the highest UV-barrier (95.5%), highest antioxidant activity (95%), potent antimicrobial activity, pH-sensitivity, lowest water vapor permeability (WVP), and desirable mechanical properties.					
35654221	8	83	theme	multifunctional	1442:1456	arg1	properties					1458:1467	The multifunctional properties	1438:1467	The multifunctional properties of the produced composite films	1438:1499	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
35654221	8	84	theme	packaging	1552:1560	arg1	films					1562:1566	active and intelligent food packaging films	1524:1566	active and intelligent food packaging films	1524:1566	The multifunctional properties of the produced composite films encourage their use as active and intelligent food packaging films to extend shelf life and monitor food quality.					
36427421	6	0	theme	CCA-Co	1103:1108	arg1	MOF					1110:1112	CCA-Co@MOF	1103:1112	CCA-Co@MOF	1103:1112	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	7	1	theme	kg-1	1392:1395	arg1	density					1375:1381	a high energy density	1361:1381	a high energy density (45.9 Wh kg-1 at 431.7 W kg-1)	1361:1412	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	1	theme	kg-1	1392:1395	arg1	431.7 W kg-1					1400:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	6	2	theme	@	1167:1167	arg1	MOFs					1168:1171	CCA-M@MOFs	1162:1171	CCA-M@MOFs (M = Ni, Zn and Cu)	1162:1191	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	3	3	theme	biomass	620:626	arg1	particles					637:645	biomass chitosan particles	620:645	biomass chitosan particles	620:645	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	3	theme	biomass	620:626	arg1	compounds					658:666	cobalt compounds	651:666	cobalt compounds	651:666	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	3	theme	biomass	620:626	arg1	materials					675:683	raw materials	671:683	raw materials	671:683	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	6	4	theme	contrast	1203:1210	arg1	materials					1212:1220	other contrast materials	1197:1220	other contrast materials	1197:1220	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	5	5	theme	Co	841:842	arg1	presence					829:836	the presence	825:836	the presence of Co	825:842	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	3	6	theme	cobalt	651:656	arg1	particles					637:645	biomass chitosan particles	620:645	biomass chitosan particles	620:645	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	6	theme	cobalt	651:656	arg1	compounds					658:666	cobalt compounds	651:666	cobalt compounds	651:666	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	6	theme	cobalt	651:656	arg1	materials					675:683	raw materials	671:683	raw materials	671:683	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	5	7	theme	chitosan	872:879	arg1	aerogel					881:887	carbonized chitosan aerogel	861:887	carbonized chitosan aerogel (CCA)	861:893	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	5	7	theme	chitosan	872:879	arg1	CCA					890:892	CCA	890:892	CCA	890:892	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	7	8	theme	activated	1318:1326	arg1	AC					1336:1337	AC	1336:1337	AC	1336:1337	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	8	theme	activated	1318:1326	arg1	carbon					1328:1333	activated carbon	1318:1333	activated carbon (AC)	1318:1338	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	4	9	theme	@	720:720	arg1	composite					703:711	Then the layered composite	686:711	Then the layered composite (CCA-Co@MOF)	686:724	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	9	theme	@	720:720	arg1	MOF					721:723	CCA-Co@MOF	714:723	CCA-Co@MOF	714:723	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	7	10	theme	MOF	1310:1312	arg1	electrodes					1340:1349	CCA-Co@MOF and activated carbon (AC) electrodes	1303:1349	CCA-Co@MOF and activated carbon (AC) electrodes	1303:1349	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	5	11	theme	electrochemical	1032:1046	arg1	performance					1048:1058	excellent electrochemical performance	1022:1058	excellent electrochemical performance	1022:1058	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	1	12	theme	intelligent	145:155	arg1	use					157:159	The intelligent use	141:159	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials	141:245	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	7	13	theme	CCA-Co	1303:1308	arg1	MOF					1310:1312	CCA-Co@MOF	1303:1312	CCA-Co@MOF	1303:1312	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	0	14	from	construction	8:19	arg1	nitrogen					69:76	chitosan-derived nitrogen	52:76	chitosan-derived nitrogen	52:76	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	4	15	theme	Ni	759:760	arg1	carrier					807:813	the carrier	803:813	the carrier	803:813	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	15	theme	Ni	759:760	arg1	MOF					762:764	Co-doped Ni MOF	750:764	Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor	750:798	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	15	theme	Ni	759:760	arg1	MOF					773:775	Co-Ni MOF	767:775	Co-Ni MOF	767:775	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	0	16	theme	porous	89:94	arg1	carbon					96:101	porous carbon	89:101	porous carbon for high-performance supercapacitors	89:138	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	1	17	theme	biomass	191:197	arg1	materials					199:207	regenerable and degradable biomass materials	164:207	regenerable and degradable biomass materials	164:207	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	2	18	theme	metal-organic	325:337	arg1	MOF					350:352	MOF	350:352	MOF	350:352	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	2	18	theme	metal-organic	325:337	arg1	framework					339:347	metal-organic framework	325:347	metal-organic framework (MOF) based cathode materials	325:377	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	6	19	dep	M = Ni	1174:1179	arg1	Cu					1189:1190	Cu	1189:1190	Cu	1189:1190	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	6	19	dep	M = Ni	1174:1179	arg1	Zn					1182:1183	Zn	1182:1183	Zn	1182:1183	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	3	20	theme	chitosan	501:508	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	21	dep	sol-gel	555:561	arg1	freeze-drying					564:576	freeze-drying	564:576	freeze-drying	564:576	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	6	22	theme	specific	1079:1086	arg1	capacitance					1088:1098	the specific capacitance	1075:1098	the specific capacitance of CCA-Co@MOF	1075:1112	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	3	23	theme	porous	483:488	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	0	24	theme	In	0:1	arg1	construction					8:19	In situ construction	0:19	In situ construction of metal-organic frameworks on chitosan-derived nitrogen	0:76	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	7	25	theme	MOF//AC	1274:1280	arg1	ASC					1282:1284	CCA-Co@MOF//AC ASC	1267:1284	CCA-Co@MOF//AC ASC	1267:1284	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	25	theme	MOF//AC	1274:1280	arg1	supercapacitor					1251:1264	the asymmetric supercapacitor	1236:1264	the asymmetric supercapacitor (CCA-Co@MOF//AC ASC)	1236:1285	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	8	26	theme	metal	1454:1458	arg1	aerogels					1506:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	5	27	theme	Co	963:964	arg1	ions					966:969	Co ions	963:969	Co ions	963:969	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	7	28	theme	CCA-Co	1267:1272	arg1	ASC					1282:1284	CCA-Co@MOF//AC ASC	1267:1284	CCA-Co@MOF//AC ASC	1267:1284	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	28	theme	CCA-Co	1267:1272	arg1	supercapacitor					1251:1264	the asymmetric supercapacitor	1236:1264	the asymmetric supercapacitor (CCA-Co@MOF//AC ASC)	1236:1285	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	3	29	theme	nitrogen	463:470	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	0	30	theme	metal-organic	24:36	arg1	frameworks					38:47	metal-organic frameworks	24:47	metal-organic frameworks	24:47	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	3	31	theme	Co	438:439	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	8	32	theme	chitosan	1497:1504	arg1	aerogels					1506:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	5	33	theme	excellent	1022:1030	arg1	performance					1048:1058	excellent electrochemical performance	1022:1058	excellent electrochemical performance	1022:1058	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	6	34	theme	F	1129:1129	arg1	g-1					1131:1133	1877.2 F g-1	1122:1133	1877.2 F g-1	1122:1133	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	1	35	theme	huge	257:260	arg1	benefits					271:278	huge economic benefits	257:278	huge economic benefits	257:278	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	8	36	theme	electrochemical	1577:1591	arg1	storage					1600:1606	electrochemical energy storage	1577:1606	electrochemical energy storage	1577:1606	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	7	37	theme	at	1397:1398	arg1	density					1375:1381	a high energy density	1361:1381	a high energy density (45.9 Wh kg-1 at 431.7 W kg-1)	1361:1412	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	37	theme	at	1397:1398	arg1	431.7 W kg-1					1400:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	5	38	theme	MOF	1004:1006	arg1	growth					994:999	the growth	990:999	the growth of MOF	990:1006	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	6	39	theme	@	1109:1109	arg1	MOF					1110:1112	CCA-Co@MOF	1103:1112	CCA-Co@MOF	1103:1112	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	2	40	theme	research	394:401	arg1	hotspot					403:409	a research hotspot	392:409	a research hotspot for supercapacitors	392:429	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	8	41	theme	storage	1600:1606	arg1	field					1568:1572	the field	1564:1572	the field of electrochemical energy storage	1564:1606	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	1	42	theme	environmental	284:296	arg1	improvements					298:309	environmental improvements	284:309	environmental improvements	284:309	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	7	43	theme	Wh	1389:1390	arg1	density					1375:1381	a high energy density	1361:1381	a high energy density (45.9 Wh kg-1 at 431.7 W kg-1)	1361:1412	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	43	theme	Wh	1389:1390	arg1	431.7 W kg-1					1400:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	8	44	theme	great	1549:1553	arg1	value					1555:1559	its great value	1545:1559	its great value	1545:1559	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	4	45	with	MOF	762:764	arg1	precursor					790:798	CCA-Co precursor	783:798	CCA-Co precursor	783:798	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	2	46	theme	framework	339:347	arg1	materials					369:377	metal-organic framework (MOF) based cathode materials	325:377	metal-organic framework (MOF) based cathode materials	325:377	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	7	47	theme	high	1363:1366	arg1	density					1375:1381	a high energy density	1361:1381	a high energy density (45.9 Wh kg-1 at 431.7 W kg-1)	1361:1412	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	47	theme	high	1363:1366	arg1	431.7 W kg-1					1400:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	3	48	theme	carbonization	592:604	arg1	process					606:612	carbonization process	592:612	carbonization process	592:612	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	1	49	theme	materials	199:207	arg1	use					157:159	The intelligent use	141:159	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials	141:245	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	7	50	theme	energy	1368:1373	arg1	density					1375:1381	a high energy density	1361:1381	a high energy density (45.9 Wh kg-1 at 431.7 W kg-1)	1361:1412	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	50	theme	energy	1368:1373	arg1	431.7 W kg-1					1400:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	0	51	link	chitosan-derived	52:67	arg1	nitrogen					69:76	chitosan-derived nitrogen	52:76	chitosan-derived nitrogen	52:76	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	6	52	theme	other	1197:1201	arg1	materials					1212:1220	other contrast materials	1197:1220	other contrast materials	1197:1220	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	2	53	theme	based	355:359	arg1	materials					369:377	metal-organic framework (MOF) based cathode materials	325:377	metal-organic framework (MOF) based cathode materials	325:377	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	3	54	theme	chitosan	628:635	arg1	particles					637:645	biomass chitosan particles	620:645	biomass chitosan particles	620:645	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	54	theme	chitosan	628:635	arg1	compounds					658:666	cobalt compounds	651:666	cobalt compounds	651:666	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	54	theme	chitosan	628:635	arg1	materials					675:683	raw materials	671:683	raw materials	671:683	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	1	55	theme	synthetic	227:235	arg1	materials					237:245	the synthetic materials	223:245	the synthetic materials	223:245	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	3	56	theme	raw	671:673	arg1	particles					637:645	biomass chitosan particles	620:645	biomass chitosan particles	620:645	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	56	theme	raw	671:673	arg1	compounds					658:666	cobalt compounds	651:666	cobalt compounds	651:666	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	3	56	theme	raw	671:673	arg1	materials					675:683	raw materials	671:683	raw materials	671:683	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	7	57	theme	carbon	1328:1333	arg1	electrodes					1340:1349	CCA-Co@MOF and activated carbon (AC) electrodes	1303:1349	CCA-Co@MOF and activated carbon (AC) electrodes	1303:1349	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	4	58	theme	CCA-Co	714:719	arg1	composite					703:711	Then the layered composite	686:711	Then the layered composite (CCA-Co@MOF)	686:724	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	58	theme	CCA-Co	714:719	arg1	MOF					721:723	CCA-Co@MOF	714:723	CCA-Co@MOF	714:723	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	5	59	theme	CCA	934:936	arg1	self-assembly					917:929	the self-assembly	913:929	the self-assembly of CCA and MOF	913:944	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	7	60	from	431.7 W kg-1	1400:1411	arg1	kg-1					1392:1395	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	60	from	431.7 W kg-1	1400:1411	arg1	at					1397:1398	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	60	from	431.7 W kg-1	1400:1411	arg1	Wh					1389:1390	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	45.9 Wh kg-1 at 431.7 W kg-1	1384:1411	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	6	61	theme	CCA-M	1162:1166	arg1	MOFs					1168:1171	CCA-M@MOFs	1162:1171	CCA-M@MOFs (M = Ni, Zn and Cu)	1162:1191	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	6	62	dep	MOFs	1168:1171	arg1	M = Ni					1174:1179	M = Ni	1174:1179	M = Ni	1174:1179	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	5	63	theme	MOF	942:944	arg1	self-assembly					917:929	the self-assembly	913:929	the self-assembly of CCA and MOF	913:944	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	7	64	theme	@	1309:1309	arg1	MOF					1310:1312	CCA-Co@MOF	1303:1312	CCA-Co@MOF	1303:1312	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	4	65	theme	Co-Ni	767:771	arg1	MOF					762:764	Co-doped Ni MOF	750:764	Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor	750:798	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	65	theme	Co-Ni	767:771	arg1	MOF					773:775	Co-Ni MOF	767:775	Co-Ni MOF	767:775	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	5	66	theme	carbonized	861:870	arg1	aerogel					881:887	carbonized chitosan aerogel	861:887	carbonized chitosan aerogel (CCA)	861:893	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	5	66	theme	carbonized	861:870	arg1	CCA					890:892	CCA	890:892	CCA	890:892	Notably, the presence of Co nanoparticles in carbonized chitosan aerogel (CCA) not only promotes the self-assembly of CCA and MOF, but also etched Co ions can participate in the growth of MOF, resulting in excellent electrochemical performance.					
36427421	1	67	theme	regenerable	164:174	arg1	materials					199:207	regenerable and degradable biomass materials	164:207	regenerable and degradable biomass materials	164:207	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	1	68	theme	degradable	180:189	arg1	materials					199:207	regenerable and degradable biomass materials	164:207	regenerable and degradable biomass materials	164:207	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	4	69	theme	Co-doped	750:757	arg1	carrier					807:813	the carrier	803:813	the carrier	803:813	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	69	theme	Co-doped	750:757	arg1	MOF					762:764	Co-doped Ni MOF	750:764	Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor	750:798	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	69	theme	Co-doped	750:757	arg1	MOF					773:775	Co-Ni MOF	767:775	Co-Ni MOF	767:775	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	0	70	theme	high-performance	107:122	arg1	supercapacitors					124:138	high-performance supercapacitors	107:138	high-performance supercapacitors	107:138	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	3	71	theme	aerogel	510:516	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	7	72	theme	@	1273:1273	arg1	ASC					1282:1284	CCA-Co@MOF//AC ASC	1267:1284	CCA-Co@MOF//AC ASC	1267:1284	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	72	theme	@	1273:1273	arg1	supercapacitor					1251:1264	the asymmetric supercapacitor	1236:1264	the asymmetric supercapacitor (CCA-Co@MOF//AC ASC)	1236:1285	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	8	73	theme	nanoparticle-modified	1460:1480	arg1	aerogels					1506:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	3	74	theme	carbonized	490:499	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	8	75	theme	carbonized	1486:1495	arg1	aerogels					1506:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	metal nanoparticle-modified and carbonized chitosan aerogels	1454:1513	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	4	76	theme	CCA-Co	783:788	arg1	precursor					790:798	CCA-Co precursor	783:798	CCA-Co precursor	783:798	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	0	77	theme	frameworks	38:47	arg1	construction					8:19	In situ construction	0:19	In situ construction of metal-organic frameworks on chitosan-derived nitrogen	0:76	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	7	78	theme	asymmetric	1240:1249	arg1	ASC					1282:1284	CCA-Co@MOF//AC ASC	1267:1284	CCA-Co@MOF//AC ASC	1267:1284	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	7	78	theme	asymmetric	1240:1249	arg1	supercapacitor					1251:1264	the asymmetric supercapacitor	1236:1264	the asymmetric supercapacitor (CCA-Co@MOF//AC ASC)	1236:1285	Furthermore, the asymmetric supercapacitor (CCA-Co@MOF//AC ASC) assembled using CCA-Co@MOF and activated carbon (AC) electrodes, exhibits a high energy density (45.9 Wh kg-1 at 431.7 W kg-1).					
36427421	3	79	theme	self-doped	472:481	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	8	80	theme	aerogels	1506:1513	arg1	advantages					1440:1449	the advantages	1436:1449	the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth	1436:1528	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	3	81	theme	CCA-Co	519:524	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	0	82	theme	chitosan-derived	52:67	arg1	nitrogen					69:76	chitosan-derived nitrogen	52:76	chitosan-derived nitrogen	52:76	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	3	83	theme	nanoparticle-modified	441:461	arg1	precursors					527:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors	438:536	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	8	84	theme	MOF	1519:1521	arg1	growth					1523:1528	MOF growth	1519:1528	MOF growth	1519:1528	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	3	85	theme	sol-gel	555:561	arg1	technique					578:586	sol-gel, freeze-drying technique	555:586	sol-gel, freeze-drying technique	555:586	Here, Co nanoparticle-modified nitrogen self-doped porous carbonized chitosan aerogel (CCA-Co) precursors were prepared by sol-gel, freeze-drying technique and carbonization process using biomass chitosan particles and cobalt compounds as raw materials.					
36427421	0	86	dep	In	0:1	arg1	situ					3:6	situ	3:6	situ	3:6	In situ construction of metal-organic frameworks on chitosan-derived nitrogen self-doped porous carbon for high-performance supercapacitors.					
36427421	2	87	theme	cathode	361:367	arg1	materials					369:377	metal-organic framework (MOF) based cathode materials	325:377	metal-organic framework (MOF) based cathode materials	325:377	In addition, metal-organic framework (MOF) based cathode materials are becoming a research hotspot for supercapacitors.					
36427421	8	88	theme	energy	1593:1598	arg1	storage					1600:1606	electrochemical energy storage	1577:1606	electrochemical energy storage	1577:1606	This work highlights the advantages of metal nanoparticle-modified and carbonized chitosan aerogels for MOF growth, demonstrating its great value in the field of electrochemical energy storage.					
36427421	1	89	theme	economic	262:269	arg1	benefits					271:278	huge economic benefits	257:278	huge economic benefits	257:278	The intelligent use of regenerable and degradable biomass materials to substitute the synthetic materials can bring huge economic benefits and environmental improvements.					
36427421	6	90	theme	MOF	1110:1112	arg1	capacitance					1088:1098	the specific capacitance	1075:1098	the specific capacitance of CCA-Co@MOF	1075:1112	Specifically, the specific capacitance of CCA-Co@MOF reaches 1877.2 F g-1, which is much superior to CCA-M@MOFs (M = Ni, Zn and Cu) and other contrast materials.					
36427421	4	91	theme	layered	695:701	arg1	composite					703:711	Then the layered composite	686:711	Then the layered composite (CCA-Co@MOF)	686:724	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36427421	4	91	theme	layered	695:701	arg1	MOF					721:723	CCA-Co@MOF	714:723	CCA-Co@MOF	714:723	Then the layered composite (CCA-Co@MOF) was obtained by growing Co-doped Ni MOF (Co-Ni MOF) with CCA-Co precursor as the carrier.					
36306912	0	0	theme	refrigerated	80:91	arg1	storage					93:99	refrigerated storage	80:99	refrigerated storage with modified atmosphere packaging	80:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	0	1	theme	golden	188:193	arg1	fillets					203:209	golden pompano fillets	188:209	golden pompano fillets	188:209	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	5	2	theme	chitosan-WSEO	1161:1173	arg1	film					1185:1188	the edible chitosan-WSEO composite film	1150:1188	the edible chitosan-WSEO composite film	1150:1188	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	5	2	theme	chitosan-WSEO	1161:1173	arg1	effective					1221:1229	effective	1221:1229	effective	1221:1229	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	2	3	theme	lowest	639:644	arg1	count					662:666	the lowest total bacterial count	635:666	the lowest total bacterial count	635:666	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	4	theme	WSEO	262:265	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	2	5	theme	film	528:531	arg1	coating					533:539	the chitosan-WSEO composite film coating	500:539	the chitosan-WSEO composite film coating	500:539	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	6	theme	quality	332:338	arg1	preservation					340:351	the quality preservation	328:351	the quality preservation of golden pompano fillets during refrigerated storage	328:405	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	7	theme	fillets	203:209	arg1	preservation					172:183	quality preservation	164:183	quality preservation of golden pompano fillets	164:209	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	3	8	theme	oxidative	987:995	arg1	deterioration					997:1009	the oxidative deterioration	983:1009	the oxidative deterioration of unsaturated fatty acids	983:1036	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	2	9	theme	composite	518:526	arg1	coating					533:539	the chitosan-WSEO composite film coating	500:539	the chitosan-WSEO composite film coating	500:539	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	0	10	theme	pompano	195:201	arg1	fillets					203:209	golden pompano fillets	188:209	golden pompano fillets	188:209	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	4	11	theme	fillets	1116:1122	arg1	deterioration					1095:1107	texture deterioration	1087:1107	texture deterioration	1087:1107	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	4	11	theme	fillets	1116:1122	arg1	changes					1063:1069	minimal color changes	1049:1069	minimal color changes	1049:1069	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	4	11	theme	fillets	1116:1122	arg1	loss					1077:1080	drip loss	1072:1080	drip loss	1072:1080	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	1	12	theme	composite	268:276	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	13	theme	atmosphere	115:124	arg1	packaging					126:134	modified atmosphere packaging	106:134	modified atmosphere packaging	106:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	2	14	theme	values	736:741	arg1	/g					782:783	peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g	703:783	peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g	703:783	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	3	15	theme	hydrolase	930:938	arg1	inhibition					906:915	the most profound inhibition	888:915	the most profound inhibition of the lipid hydrolase, lipoxygenase	888:952	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	0	16	theme	modified	106:113	arg1	packaging					126:134	modified atmosphere packaging	106:134	modified atmosphere packaging	106:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	1	17	theme	golden	356:361	arg1	fillets					371:377	golden pompano fillets	356:377	golden pompano fillets	356:377	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	3	18	theme	unsaturated	1014:1024	arg1	acids					1032:1036	unsaturated fatty acids	1014:1036	unsaturated fatty acids	1014:1036	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	2	19	theme	1428.4 μg	820:828	arg1	MDAeq/kg					830:837	1428.4 μg MDAeq/kg	820:837	1428.4 μg MDAeq/kg	820:837	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	20	theme	acid	731:734	arg1	values					736:741	thiobarbituric acid values	716:741	thiobarbituric acid values of 4.03 log culture-forming units (CFU)	716:781	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	21	theme	chitosan-WSEO	504:516	arg1	coating					533:539	the chitosan-WSEO composite film coating	500:539	the chitosan-WSEO composite film coating	500:539	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	22	theme	pompano	363:369	arg1	fillets					371:377	golden pompano fillets	356:377	golden pompano fillets	356:377	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	3	23	theme	fatty	1026:1030	arg1	acids					1032:1036	unsaturated fatty acids	1014:1036	unsaturated fatty acids	1014:1036	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	2	24	theme	thiobarbituric	716:729	arg1	values					736:741	thiobarbituric acid values	716:741	thiobarbituric acid values of 4.03 log culture-forming units (CFU)	716:781	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	25	theme	film	278:281	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	2	26	theme	bacterial	652:660	arg1	count					662:666	the lowest total bacterial count	635:666	the lowest total bacterial count	635:666	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	27	theme	units	771:775	arg1	values					736:741	thiobarbituric acid values	716:741	thiobarbituric acid values of 4.03 log culture-forming units (CFU)	716:781	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	27	theme	units	771:775	arg1	peroxide					703:710	peroxide	703:710	peroxide	703:710	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	0	28	theme	oil	31:33	arg1	film					45:48	essential oil composite film	21:48	essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging	21:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	1	29	theme	coating	283:289	arg1	effect					216:221	The effect	212:221	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage	212:405	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	30	with	storage	93:99	arg1	packaging					126:134	modified atmosphere packaging	106:134	modified atmosphere packaging	106:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	2	31	theme	culture-forming	755:769	arg1	CFU					778:780	CFU	778:780	CFU	778:780	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	31	theme	culture-forming	755:769	arg1	units					771:775	4.03 log culture-forming units	746:775	4.03 log culture-forming units (CFU)	746:781	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	0	32	theme	essential	21:29	arg1	film					45:48	essential oil composite film	21:48	essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging	21:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	2	33	theme	CP	548:549	arg1	treatment					551:559	CP treatment	548:559	CP treatment	548:559	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	34	theme	fillets	371:377	arg1	preservation					340:351	the quality preservation	328:351	the quality preservation of golden pompano fillets during refrigerated storage	328:405	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	2	35	theme	log	751:753	arg1	CFU					778:780	CFU	778:780	CFU	778:780	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	35	theme	log	751:753	arg1	units					771:775	4.03 log culture-forming units	746:775	4.03 log culture-forming units (CFU)	746:781	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	3	36	theme	profound	897:904	arg1	inhibition					906:915	the most profound inhibition	888:915	the most profound inhibition of the lipid hydrolase, lipoxygenase	888:952	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	5	37	theme	edible	1154:1159	arg1	film					1185:1188	the edible chitosan-WSEO composite film	1150:1188	the edible chitosan-WSEO composite film	1150:1188	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	5	37	theme	edible	1154:1159	arg1	effective					1221:1229	effective	1221:1229	effective	1221:1229	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	1	38	theme	cold	298:301	arg1	treatment					315:323	cold plasma (CP) treatment	298:323	cold plasma (CP) treatment	298:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	39	theme	promising	139:147	arg1	technology					149:158	A promising technology	137:158	A promising technology for quality preservation of golden pompano fillets	137:209	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	5	40	theme	shelf	1282:1286	arg1	life					1288:1291	shelf life	1282:1291	shelf life	1282:1291	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	5	41	theme	refrigerated	1308:1319	arg1	period					1329:1334	the refrigerated storage period	1304:1334	the refrigerated storage period	1304:1334	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	0	42	theme	composite	35:43	arg1	film					45:48	essential oil composite film	21:48	essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging	21:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	1	43	theme	plasma	303:308	arg1	treatment					315:323	cold plasma (CP) treatment	298:323	cold plasma (CP) treatment	298:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	5	44	theme	composite	1175:1183	arg1	film					1185:1188	the edible chitosan-WSEO composite film	1150:1188	the edible chitosan-WSEO composite film	1150:1188	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	5	44	theme	composite	1175:1183	arg1	effective					1221:1229	effective	1221:1229	effective	1221:1229	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	1	45	theme	refrigerated	386:397	arg1	storage					399:405	refrigerated storage	386:405	refrigerated storage	386:405	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	1	46	from	effect	216:221	arg1	preservation					340:351	the quality preservation	328:351	the quality preservation of golden pompano fillets during refrigerated storage	328:405	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	4	47	theme	texture	1087:1093	arg1	deterioration					1095:1107	texture deterioration	1087:1107	texture deterioration	1087:1107	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	2	48	theme	base	684:687	arg1	nitrogen					689:696	total volatile base nitrogen	669:696	total volatile base nitrogen	669:696	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	1	49	theme	CP	311:312	arg1	treatment					315:323	cold plasma (CP) treatment	298:323	cold plasma (CP) treatment	298:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	2	50	theme	atmosphere	574:583	arg1	MAP					596:598	MAP	596:598	MAP	596:598	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	50	theme	atmosphere	574:583	arg1	packaging					585:593	modified atmosphere packaging	565:593	modified atmosphere packaging (MAP)	565:599	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	51	theme	volatile	675:682	arg1	nitrogen					689:696	total volatile base nitrogen	669:696	total volatile base nitrogen	669:696	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	3	52	theme	acids	1032:1036	arg1	deterioration					997:1009	the oxidative deterioration	983:1009	the oxidative deterioration of unsaturated fatty acids	983:1036	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	4	53	theme	color	1057:1061	arg1	changes					1063:1069	minimal color changes	1049:1069	minimal color changes	1049:1069	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	2	54	theme	total	646:650	arg1	count					662:666	the lowest total bacterial count	635:666	the lowest total bacterial count	635:666	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	55	theme	modified	565:572	arg1	MAP					596:598	MAP	596:598	MAP	596:598	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	55	theme	modified	565:572	arg1	packaging					585:593	modified atmosphere packaging	565:593	modified atmosphere packaging (MAP)	565:599	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	2	56	theme	total	669:673	arg1	nitrogen					689:696	total volatile base nitrogen	669:696	total volatile base nitrogen	669:696	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	4	57	theme	minimal	1049:1055	arg1	changes					1063:1069	minimal color changes	1049:1069	minimal color changes	1049:1069	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	1	58	theme	chitosan-wampee	226:240	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	59	theme	quality	164:170	arg1	preservation					172:183	quality preservation	164:183	quality preservation of golden pompano fillets	164:209	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	3	60	theme	lipid	924:928	arg1	lipoxygenase					941:952	lipoxygenase	941:952	lipoxygenase	941:952	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	3	60	theme	lipid	924:928	arg1	hydrolase					930:938	the lipid hydrolase	920:938	the lipid hydrolase	920:938	Simultaneously, it contributed to the most profound inhibition of the lipid hydrolase, lipoxygenase, thus effectively preventing the oxidative deterioration of unsaturated fatty acids.					
36306912	5	61	theme	storage	1321:1327	arg1	period					1329:1334	the refrigerated storage period	1304:1334	the refrigerated storage period	1304:1334	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	4	62	theme	drip	1072:1075	arg1	loss					1077:1080	drip loss	1072:1080	drip loss	1072:1080	Moreover, minimal color changes, drip loss, and texture deterioration of the fillets were observed.					
36306912	5	63	theme	golden	1245:1250	arg1	fillets					1260:1266	golden pompano fillets	1245:1266	golden pompano fillets	1245:1266	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	1	64	theme	seed	242:245	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	2	65	theme	peroxide	703:710	arg1	/g					782:783	peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g	703:783	peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g	703:783	The results indicated that the chitosan-WSEO composite film coating before CP treatment and modified atmosphere packaging (MAP), referred to as CPCW-M, exhibited the lowest total bacterial count, total volatile base nitrogen, and peroxide and thiobarbituric acid values of 4.03 log culture-forming units (CFU)/g, 13.45 mg/100 g, 24.65 meq/kg, and 1428.4 μg MDAeq/kg, respectively.					
36306912	5	66	theme	pompano	1252:1258	arg1	fillets					1260:1266	golden pompano fillets	1245:1266	golden pompano fillets	1245:1266	Therefore, the edible chitosan-WSEO composite film, together with CP and MAP, was effective in preserving golden pompano fillets and extending shelf life throughout the refrigerated storage period.					
36306912	1	67	theme	essential	247:255	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
36306912	0	68	theme	cold	64:67	arg1	plasma					69:74	cold plasma	64:74	cold plasma for refrigerated storage with modified atmosphere packaging	64:134	Chitosan-wampee seed essential oil composite film combined with cold plasma for refrigerated storage with modified atmosphere packaging: A promising technology for quality preservation of golden pompano fillets.					
36306912	1	69	theme	oil	257:259	arg1	coating					283:289	chitosan-wampee seed essential oil (WSEO) composite film coating	226:289	chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment	226:323	The effect of chitosan-wampee seed essential oil (WSEO) composite film coating before cold plasma (CP) treatment on the quality preservation of golden pompano fillets during refrigerated storage was investigated and compared with that of chitosan and CP alone.					
35015143	3	0	theme	L.	348:349	arg1	19,115					370:375	L. monocytogenes ATCC 19,115	348:375	L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA)	348:448	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	8	1	from	Changes	1102:1108	arg1	response					1142:1149	response	1142:1149	response to treatments	1142:1163	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	5	2	theme	minimal	691:697	arg1	MBC					727:729	MBC	727:729	MBC	727:729	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	2	theme	minimal	691:697	arg1	concentration					712:724	the minimal bactericidal concentration	687:724	the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes	687:765	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	2	theme	minimal	691:697	arg1	25 μg/mL					772:779	25 μg/mL	772:779	25 μg/mL	772:779	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	8	3	theme	carbohydrate	1188:1199	arg1	metabolism					1201:1210	carbohydrate metabolism	1188:1210	carbohydrate metabolism	1188:1210	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	9	4	theme	molecular	1380:1388	arg1	mechanisms					1390:1399	the molecular mechanisms	1376:1399	the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes	1376:1473	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	5	5	theme	bactericidal	699:710	arg1	MBC					727:729	MBC	727:729	MBC	727:729	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	5	theme	bactericidal	699:710	arg1	concentration					712:724	the minimal bactericidal concentration	687:724	the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes	687:765	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	5	theme	bactericidal	699:710	arg1	25 μg/mL					772:779	25 μg/mL	772:779	25 μg/mL	772:779	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	6	theme	minimum	644:650	arg1	MIC					678:680	MIC	678:680	MIC	678:680	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	6	theme	minimum	644:650	arg1	concentration					663:675	The minimum inhibitory concentration	640:675	The minimum inhibitory concentration (MIC)	640:681	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	6	theme	minimum	644:650	arg1	25 μg/mL					772:779	25 μg/mL	772:779	25 μg/mL	772:779	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	9	7	theme	HBA/HP-β-CD	1528:1538	arg1	agents					1554:1559	HBA/HP-β-CD antimicrobial agents	1528:1559	HBA/HP-β-CD antimicrobial agents	1528:1559	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	8	8	theme	composition	1241:1251	arg1	proteins					1253:1260	ribosome composition proteins	1232:1260	ribosome composition proteins	1232:1260	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	8	9	theme	L.	1113:1114	arg1	proteome					1130:1137	L. monocytogenes proteome	1113:1137	L. monocytogenes proteome	1113:1137	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	5	10	theme	inhibitory	652:661	arg1	MIC					678:680	MIC	678:680	MIC	678:680	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	10	theme	inhibitory	652:661	arg1	concentration					663:675	The minimum inhibitory concentration	640:675	The minimum inhibitory concentration (MIC)	640:681	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	10	theme	inhibitory	652:661	arg1	25 μg/mL					772:779	25 μg/mL	772:779	25 μg/mL	772:779	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	1	11	theme	Food	101:104	arg1	safety					106:111	Food safety	101:111	Food safety affected by food-borne pathogen	101:143	Food safety affected by food-borne pathogen has received increasing attention by researchers.					
35015143	9	12	theme	antimicrobial	1540:1552	arg1	agents					1554:1559	HBA/HP-β-CD antimicrobial agents	1528:1559	HBA/HP-β-CD antimicrobial agents	1528:1559	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	2	13	from	widespread	238:247	arg1	environment					256:266	the environment	252:266	the environment	252:266	Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases.					
35015143	3	14	from	proteome	402:409	arg1	response					414:421	response	414:421	response to hexahydro-β-acids (HBA)	414:448	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	9	15	theme	agents	1554:1559	arg1	development					1513:1523	further development	1505:1523	further development of HBA/HP-β-CD antimicrobial agents	1505:1559	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	2	16	from	environment	256:266	arg1	widespread					238:247	widespread	238:247	widespread	238:247	Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases.					
35015143	10	17	theme	KEY	1562:1564	arg1	POINTS					1566:1571	KEY POINTS	1562:1571	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.	1562:1650	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	10	17	theme	KEY	1562:1564	arg1	100 μg/mL					1641:1649	100 μg/mL	1641:1649	100 μg/mL	1641:1649	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	10	17	theme	KEY	1562:1564	arg1	25 μg/mL					1628:1635	25 μg/mL	1628:1635	25 μg/mL	1628:1635	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	8	18	theme	proteome	1130:1137	arg1	Changes					1102:1108	Changes	1102:1108	Changes of L. monocytogenes proteome in response to treatments	1102:1163	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	12	19	theme	ribosome	1732:1739	arg1	composition					1741:1751	ribosome composition	1732:1751	ribosome composition	1732:1751	• The process of ribosome composition and carbohydrate metabolism was inhibited.					
35015143	10	20	dep	POINTS	1566:1571	arg1	POINTS					1566:1571	KEY POINTS	1562:1571	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.	1562:1650	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	10	20	dep	POINTS	1566:1571	arg1	100 μg/mL					1641:1649	100 μg/mL	1641:1649	100 μg/mL	1641:1649	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	10	20	dep	POINTS	1566:1571	arg1	25 μg/mL					1628:1635	25 μg/mL	1628:1635	25 μg/mL	1628:1635	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	2	21	theme	Listeria	195:202	arg1	monocytogenes					204:216	Listeria monocytogenes	195:216	Listeria monocytogenes (L. monocytogenes)	195:235	Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases.					
35015143	8	22	theme	cell	1263:1266	arg1	proteins					1285:1292	cell wall composition proteins	1263:1292	cell wall composition proteins	1263:1292	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	8	23	theme	anomalies	1313:1321	arg1	process					1323:1329	cell division anomalies process	1299:1329	cell division anomalies process	1299:1329	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	8	24	theme	wall	1268:1271	arg1	proteins					1285:1292	cell wall composition proteins	1263:1292	cell wall composition proteins	1263:1292	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	8	25	theme	protein	1213:1219	arg1	synthesis					1221:1229	protein synthesis	1213:1229	protein synthesis	1213:1229	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	1	26	theme	food-borne	125:134	arg1	pathogen					136:143	food-borne pathogen	125:143	food-borne pathogen	125:143	Food safety affected by food-borne pathogen has received increasing attention by researchers.					
35015143	0	27	theme	Proteomic	0:8	arg1	analysis					10:17	Proteomic analysis	0:17	Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin	0:67	Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin inhibit Listeria monocytogenes.					
35015143	10	28	theme	•	1574:1574	arg1	MIC					1576:1578	• MIC	1574:1578	• MIC	1574:1578	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	3	29	theme	inclusion	457:465	arg1	complex					467:473	inclusion complex	457:473	inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD)	457:517	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	0	30	theme	hexahydro-β-acids/hydroxypropyl-β-cyclodextrin	22:67	arg1	analysis					10:17	Proteomic analysis	0:17	Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin	0:67	Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin inhibit Listeria monocytogenes.					
35015143	9	31	theme	HBA/HP-β-CD	1438:1448	arg1	effects					1427:1433	the inhibiting effects	1412:1433	the inhibiting effects of HBA/HP-β-CD against L. monocytogenes	1412:1473	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	3	32	dep	L.	348:349	arg1	monocytogenes					351:363	monocytogenes	351:363	monocytogenes	351:363	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	6	33	theme	microscope	828:837	arg1	images					845:850	Scanning electron microscope (SEM) images	810:850	Scanning electron microscope (SEM) images	810:850	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	11	34	theme	•	1652:1652	arg1	HBA/HP-β-CD					1654:1664	• HBA/HP-β-CD	1652:1664	• HBA/HP-β-CD	1652:1664	• HBA/HP-β-CD cause significant changes in bacterial proteome.					
35015143	8	35	theme	composition	1273:1283	arg1	proteins					1285:1292	cell wall composition proteins	1263:1292	cell wall composition proteins	1263:1292	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	4	36	theme	HBA	617:619	arg1	solubility					603:612	the solubility	599:612	the solubility of HBA to 0.589 g/100 mL	599:637	HP-β-CD enhanced the solubility of HBA to 0.589 g/100 mL.					
35015143	3	37	theme	study	319:323	arg1	aim					307:309	The aim	303:309	The aim of this study	303:323	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	6	38	theme	monocytogenes	912:924	arg1	membrane					897:904	the cell membrane	888:904	the cell membrane of L. monocytogenes	888:924	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	12	39	theme	metabolism	1770:1779	arg1	process					1721:1727	The process	1717:1727	The process of ribosome composition and carbohydrate metabolism	1717:1779	• The process of ribosome composition and carbohydrate metabolism was inhibited.					
35015143	0	40	theme	Listeria	77:84	arg1	monocytogenes					86:98	Listeria monocytogenes	77:98	Listeria monocytogenes	77:98	Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin inhibit Listeria monocytogenes.					
35015143	2	41	dep	monocytogenes	204:216	arg1	monocytogenes					222:234	L. monocytogenes	219:234	L. monocytogenes	219:234	Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases.					
35015143	10	42	theme	HBA/HP-β-CD	1591:1601	arg1	MIC					1576:1578	• MIC	1574:1578	• MIC	1574:1578	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	10	42	theme	HBA/HP-β-CD	1591:1601	arg1	MBC					1584:1586	MBC	1584:1586	MBC	1584:1586	KEY POINTS: • MIC and MBC of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL.					
35015143	12	43	theme	carbohydrate	1757:1768	arg1	metabolism					1770:1779	carbohydrate metabolism	1757:1779	carbohydrate metabolism	1757:1779	• The process of ribosome composition and carbohydrate metabolism was inhibited.					
35015143	3	44	dep	19,115	370:375	arg1	shaped					391:396	shaped	391:396	shaped its proteome in response to hexahydro-β-acids (HBA)	391:448	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	3	44	dep	19,115	370:375	arg1	regulated					377:385	regulated	377:385	regulated	377:385	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	6	45	theme	electron	819:826	arg1	SEM					840:842	SEM	840:842	SEM	840:842	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	6	45	theme	electron	819:826	arg1	microscope					828:837	Scanning electron microscope	810:837	Scanning electron microscope (SEM) images	810:850	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	9	46	theme	novel	1486:1490	arg1	insights					1492:1499	novel insights	1486:1499	novel insights	1486:1499	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	8	47	theme	division	1304:1311	arg1	process					1323:1329	cell division anomalies process	1299:1329	cell division anomalies process	1299:1329	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	8	48	dep	L.	1113:1114	arg1	monocytogenes					1116:1128	monocytogenes	1116:1128	monocytogenes	1116:1128	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	6	49	theme	Scanning	810:817	arg1	SEM					840:842	SEM	840:842	SEM	840:842	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	6	49	theme	Scanning	810:817	arg1	microscope					828:837	Scanning electron microscope	810:837	Scanning electron microscope (SEM) images	810:850	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	1	50	theme	increasing	158:167	arg1	attention					169:177	increasing attention	158:177	increasing attention	158:177	Food safety affected by food-borne pathogen has received increasing attention by researchers.					
35015143	8	51	theme	cell	1299:1302	arg1	process					1323:1329	cell division anomalies process	1299:1329	cell division anomalies process	1299:1329	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
35015143	6	52	theme	cell	892:895	arg1	membrane					897:904	the cell membrane	888:904	the cell membrane of L. monocytogenes	888:924	Scanning electron microscope (SEM) images demonstrated that HBA could destroy the cell membrane of L. monocytogenes.					
35015143	11	53	theme	bacterial	1695:1703	arg1	proteome					1705:1712	bacterial proteome	1695:1712	bacterial proteome	1695:1712	• HBA/HP-β-CD cause significant changes in bacterial proteome.					
35015143	3	54	theme	untreated	532:540	arg1	cells					542:546	untreated cells	532:546	untreated cells growing under optimal conditions	532:579	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	7	55	theme	2882	964:967	arg1	proteins					969:976	2882 proteins	964:976	2882 proteins	964:976	The proteomic analysis revealed that 2882 proteins were initially identified, among which 153 and 201 proteins were differentially upregulated and downregulated respectively.					
35015143	9	56	theme	inhibiting	1416:1425	arg1	effects					1427:1433	the inhibiting effects	1412:1433	the inhibiting effects of HBA/HP-β-CD against L. monocytogenes	1412:1473	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	3	57	with	complex	467:473	arg1	HP-β-CD					510:516	HP-β-CD	510:516	HP-β-CD	510:516	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	3	57	with	complex	467:473	arg1	hydroxypropyl-β-cyclodextrin					480:507	hydroxypropyl-β-cyclodextrin	480:507	hydroxypropyl-β-cyclodextrin (HP-β-CD)	480:517	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	11	58	from	changes	1684:1690	arg1	proteome					1705:1712	bacterial proteome	1695:1712	bacterial proteome	1695:1712	• HBA/HP-β-CD cause significant changes in bacterial proteome.					
35015143	11	59	theme	significant	1672:1682	arg1	changes					1684:1690	significant changes	1672:1690	significant changes in bacterial proteome	1672:1712	• HBA/HP-β-CD cause significant changes in bacterial proteome.					
35015143	5	60	theme	HBA/HP-β-CD	735:745	arg1	concentration					712:724	the minimal bactericidal concentration	687:724	the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes	687:765	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	60	theme	HBA/HP-β-CD	735:745	arg1	MIC					678:680	MIC	678:680	MIC	678:680	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	60	theme	HBA/HP-β-CD	735:745	arg1	concentration					663:675	The minimum inhibitory concentration	640:675	The minimum inhibitory concentration (MIC)	640:681	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	60	theme	HBA/HP-β-CD	735:745	arg1	MBC					727:729	MBC	727:729	MBC	727:729	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	5	60	theme	HBA/HP-β-CD	735:745	arg1	25 μg/mL					772:779	25 μg/mL	772:779	25 μg/mL	772:779	The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of HBA/HP-β-CD to L. monocytogenes were 25 μg/mL and 100 μg/mL, respectively.					
35015143	12	61	theme	composition	1741:1751	arg1	process					1721:1727	The process	1717:1727	The process of ribosome composition and carbohydrate metabolism	1717:1779	• The process of ribosome composition and carbohydrate metabolism was inhibited.					
35015143	3	62	theme	ATCC	365:368	arg1	19,115					370:375	L. monocytogenes ATCC 19,115	348:375	L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA)	348:448	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	2	63	theme	widespread	238:247	arg1	monocytogenes					204:216	Listeria monocytogenes	195:216	Listeria monocytogenes (L. monocytogenes)	195:235	Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases.					
35015143	9	64	theme	further	1505:1511	arg1	development					1513:1523	further development	1505:1523	further development of HBA/HP-β-CD antimicrobial agents	1505:1559	This research is conducive to understanding the molecular mechanisms underlying the inhibiting effects of HBA/HP-β-CD against L. monocytogenes, providing novel insights for further development of HBA/HP-β-CD antimicrobial agents.					
35015143	3	65	theme	optimal	562:568	arg1	conditions					570:579	optimal conditions	562:579	optimal conditions	562:579	The aim of this study was to investigate how L. monocytogenes ATCC 19,115 regulated and shaped its proteome in response to hexahydro-β-acids (HBA) formed inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD), compared to untreated cells growing under optimal conditions.					
35015143	7	66	theme	proteomic	931:939	arg1	analysis					941:948	The proteomic analysis	927:948	The proteomic analysis	927:948	The proteomic analysis revealed that 2882 proteins were initially identified, among which 153 and 201 proteins were differentially upregulated and downregulated respectively.					
35015143	8	67	theme	ribosome	1232:1239	arg1	proteins					1253:1260	ribosome composition proteins	1232:1260	ribosome composition proteins	1232:1260	Changes of L. monocytogenes proteome in response to treatments were mainly related to carbohydrate metabolism, protein synthesis, ribosome composition proteins, cell wall composition proteins, and cell division anomalies process.					
37001775	2	0	theme	gels	432:435	arg1	G					425:425	G'	425:426	G'	425:426	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	0	theme	gels	432:435	arg1	modulus					416:422	the storage modulus	404:422	the storage modulus (G') of gels with APS	404:444	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	0	theme	gels	432:435	arg1	lower					465:469	lower	465:469	lower	465:469	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	0	1	theme	polysaccharide	167:180	arg1	effect					146:151	The effect	142:151	The effect of Astragalus polysaccharide	142:180	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	5	2	theme	0.12 	1067:1071	arg1	%					1072:1072	%	1072:1072	%	1072:1072	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	2	3	dep	hardness	572:579	arg1	the					568:570	the	568:570	the	568:570	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	1	4	theme	rheological	233:243	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	0	5	theme	starch	70:75	arg1	properties					46:55	Rheological, textural, and water-immobilizing properties	0:55	Rheological, textural, and water-immobilizing properties of mung bean starch	0:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	1	6	theme	MBS	323:325	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	0	7	theme	Astragalus	156:165	arg1	polysaccharide					167:180	Astragalus polysaccharide	156:180	Astragalus polysaccharide	156:180	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	2	8	with	gels	432:435	arg1	APS					442:444	APS	442:444	APS	442:444	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	6	9	theme	gel	1376:1378	arg1	properties					1380:1389	gel properties	1376:1389	gel properties	1376:1389	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	4	10	theme	complex	810:816	arg1	network					818:824	a complex network	808:824	a complex network with reduced pore size	808:847	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	0	11	theme	protein	90:96	arg1	gels					108:111	protein composite gels	90:111	protein composite gels	90:111	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	6	12	theme	gel	1346:1348	arg1	network					1350:1356	strengthened gel network	1333:1356	strengthened gel network	1333:1356	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	5	13	with	gel	1058:1060	arg1	APS					1074:1076	0.12 % APS	1067:1076	0.12 % APS	1067:1076	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	1	14	theme	textural	246:253	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	4	15	theme	control	875:881	arg1	MBS/FP					888:893	the control gel (MBS/FP)	871:894	the control gel (MBS/FP)	871:894	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	1	16	theme	/flaxseed	327:335	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	5	17	theme	%	1072:1072	arg1	APS					1074:1076	0.12 % APS	1067:1076	0.12 % APS	1067:1076	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	18	with	gels	982:985	arg1	contents					996:1003	APS contents	992:1003	APS contents below 0.09 %	992:1016	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	6	19	theme	hydrogen	1274:1281	arg1	bonding					1283:1289	hydrogen bonding	1274:1289	hydrogen bonding	1274:1289	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	1	20	theme	protein	337:343	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	4	21	theme	composite	783:791	arg1	gels					793:796	the MBS/FP/APS composite gels	768:796	the MBS/FP/APS composite gels	768:796	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	6	22	theme	properties	1380:1389	arg1	network					1350:1356	strengthened gel network	1333:1356	strengthened gel network	1333:1356	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	6	22	theme	properties	1380:1389	arg1	change					1366:1371	the change	1362:1371	the change of gel properties	1362:1389	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	5	23	theme	International	897:909	arg1	tests					961:965	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	0	24	theme	composite	98:106	arg1	gels					108:111	protein composite gels	90:111	protein composite gels	90:111	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	6	25	theme	composite	1217:1225	arg1	systems					1227:1233	the tri-polymeric composite systems	1199:1233	the tri-polymeric composite systems	1199:1233	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	4	26	theme	MBS/FP/APS	772:781	arg1	gels					793:796	the MBS/FP/APS composite gels	768:796	the MBS/FP/APS composite gels	768:796	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	2	27	theme	gels	616:619	arg1	gumminess					582:590	gumminess	582:590	gumminess	582:590	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	27	theme	gels	616:619	arg1	hardness					572:579	hardness	572:579	hardness	572:579	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	27	theme	gels	616:619	arg1	cohesiveness					596:607	cohesiveness	596:607	cohesiveness	596:607	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	28	theme	storage	408:414	arg1	G					425:425	G'	425:426	G'	425:426	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	28	theme	storage	408:414	arg1	modulus					416:422	the storage modulus	404:422	the storage modulus (G') of gels with APS	404:444	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	28	theme	storage	408:414	arg1	lower					465:469	lower	465:469	lower	465:469	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	3	29	dep	trapping	688:695	arg1	water					723:727	more immobilized and free water	697:727	trapping more immobilized and free water	688:727	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	3	30	theme	immobilized	702:712	arg1	water					723:727	more immobilized and free water	697:727	trapping more immobilized and free water	688:727	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	6	31	theme	change	1366:1371	arg1	formation					1320:1328	the formation	1316:1328	the formation of strengthened gel network and the change of gel properties	1316:1389	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	1	32	theme	FP	346:347	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	4	33	theme	gel	883:885	arg1	MBS/FP					888:893	the control gel (MBS/FP)	871:894	the control gel (MBS/FP)	871:894	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	3	34	theme	retention	666:674	arg1	capacity					676:683	the water retention capacity	656:683	the water retention capacity	656:683	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	0	35	theme	Rheological	0:10	arg1	properties					46:55	Rheological, textural, and water-immobilizing properties	0:55	Rheological, textural, and water-immobilizing properties of mung bean starch	0:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	1	36	theme	water-holding	256:268	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	2	37	theme	diverse	549:555	arg1	effects					557:563	diverse effects	549:563	diverse effects on the hardness, gumminess and cohesiveness of the gels	549:619	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	38	theme	APS	535:537	arg1	concentrations					517:530	different concentrations	507:530	different concentrations of APS	507:537	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	7	39	theme	FP-based	1582:1589	arg1	foods					1595:1599	the FP-based gel foods	1578:1599	the FP-based gel foods	1578:1599	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	0	40	theme	potential	116:124	arg1	food					136:139	potential dysphagia food	116:139	potential dysphagia food	116:139	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	0	41	theme	textural	13:20	arg1	properties					46:55	Rheological, textural, and water-immobilizing properties	0:55	Rheological, textural, and water-immobilizing properties of mung bean starch	0:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	6	42	theme	starch	1248:1253	arg1	gelatinization					1255:1268	starch gelatinization	1248:1268	starch gelatinization	1248:1268	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	7	43	theme	structural	1458:1467	arg1	properties					1482:1491	the structural and textural properties	1454:1491	the structural and textural properties of the starch-protein composite systems	1454:1531	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	7	44	theme	gel	1591:1593	arg1	foods					1595:1599	the FP-based gel foods	1578:1599	the FP-based gel foods	1578:1599	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	0	45	theme	water-immobilizing	27:44	arg1	properties					46:55	Rheological, textural, and water-immobilizing properties	0:55	Rheological, textural, and water-immobilizing properties of mung bean starch	0:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	1	46	theme	microstructural	275:289	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	1	47	theme	composite	350:358	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	3	48	theme	water	660:664	arg1	capacity					676:683	the water retention capacity	656:683	the water retention capacity	656:683	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	1	49	theme	Astragalus	198:207	arg1	APS					225:227	APS	225:227	APS	225:227	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	1	49	theme	Astragalus	198:207	arg1	polysaccharide					209:222	Astragalus polysaccharide	198:222	Astragalus polysaccharide (APS)	198:228	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	6	50	theme	strengthened	1333:1344	arg1	network					1350:1356	strengthened gel network	1333:1356	strengthened gel network	1333:1356	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	2	51	from	effects	557:563	arg1	gumminess					582:590	gumminess	582:590	gumminess	582:590	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	51	from	effects	557:563	arg1	hardness					572:579	hardness	572:579	hardness	572:579	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	51	from	effects	557:563	arg1	cohesiveness					596:607	cohesiveness	596:607	cohesiveness	596:607	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	0	52	theme	dysphagia	126:134	arg1	food					136:139	potential dysphagia food	116:139	potential dysphagia food	116:139	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	1	53	theme	gels	360:363	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	1	54	theme	polysaccharide	209:222	arg1	effects					187:193	The effects	183:193	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	183:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	7	55	theme	various	1545:1551	arg1	properties					1564:1573	various functional properties	1545:1573	various functional properties	1545:1573	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	3	56	theme	free	718:721	arg1	water					723:727	more immobilized and free water	697:727	trapping more immobilized and free water	688:727	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	2	57	theme	different	507:515	arg1	concentrations					517:530	different concentrations	507:530	different concentrations of APS	507:537	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	7	58	theme	macromolecular	1423:1436	arg1	APS					1438:1440	the macromolecular APS	1419:1440	the macromolecular APS	1419:1440	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	7	59	theme	textural	1473:1480	arg1	properties					1482:1491	the structural and textural properties	1454:1491	the structural and textural properties of the starch-protein composite systems	1454:1531	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	1	60	theme	mung	305:308	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	2	61	theme	control	488:494	arg1	gel					496:498	the control gel	484:498	the control gel	484:498	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	1	62	from	effects	187:193	arg1	properties					291:300	rheological, textural, water-holding, and microstructural properties	233:300	rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels	233:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	1	63	theme	bean	310:313	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	6	64	theme	tri-polymeric	1203:1215	arg1	systems					1227:1233	the tri-polymeric composite systems	1199:1233	the tri-polymeric composite systems	1199:1233	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	5	65	theme	diet	921:924	arg1	initiative					942:951	dysphagia diet standardization initiative	911:951	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	65	theme	diet	921:924	arg1	IDDSI					954:958	IDDSI	954:958	IDDSI	954:958	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	4	66	with	network	818:824	arg1	size					844:847	reduced pore size	831:847	reduced pore size	831:847	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	3	67	theme	gel	736:738	arg1	network					740:746	the gel network	732:746	the gel network	732:746	Adding APS significantly improved the water retention capacity by trapping more immobilized and free water in the gel network.					
37001775	5	68	theme	dysphagia	911:919	arg1	initiative					942:951	dysphagia diet standardization initiative	911:951	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	68	theme	dysphagia	911:919	arg1	IDDSI					954:958	IDDSI	954:958	IDDSI	954:958	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	69	theme	standardization	926:940	arg1	initiative					942:951	dysphagia diet standardization initiative	911:951	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	69	theme	standardization	926:940	arg1	IDDSI					954:958	IDDSI	954:958	IDDSI	954:958	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	7	70	theme	functional	1553:1562	arg1	properties					1564:1573	various functional properties	1545:1573	various functional properties	1545:1573	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	0	71	theme	bean	65:68	arg1	starch					70:75	mung bean starch	60:75	mung bean starch	60:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	5	72	theme	APS	992:994	arg1	contents					996:1003	APS contents	992:1003	APS contents below 0.09 %	992:1016	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	5	73	theme	initiative	942:951	arg1	tests					961:965	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests	897:965	International dysphagia diet standardization initiative (IDDSI) tests suggested that gels with APS contents below 0.09 % could be classified into level 6, while gel with 0.12 % APS could be categorized as level 7.					
37001775	4	74	theme	reduced	831:837	arg1	size					844:847	reduced pore size	831:847	reduced pore size	831:847	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	2	75	contain	possessed	539:547	arg1	concentrations					517:530	different concentrations	507:530	different concentrations of APS	507:537	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	2	75	contain	possessed	539:547	arg2	effects					557:563	diverse effects	549:563	diverse effects on the hardness, gumminess and cohesiveness of the gels	549:619	Results showed that the storage modulus (G') of gels with APS were significantly lower than that of the control gel, while different concentrations of APS possessed diverse effects on the hardness, gumminess and cohesiveness of the gels.					
37001775	7	76	theme	starch-protein	1500:1513	arg1	systems					1525:1531	the starch-protein composite systems	1496:1531	the starch-protein composite systems	1496:1531	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	0	77	theme	mung	60:63	arg1	bean					65:68	mung bean	60:68	mung bean starch	60:75	Rheological, textural, and water-immobilizing properties of mung bean starch and flaxseed protein composite gels as potential dysphagia food: The effect of Astragalus polysaccharide.					
37001775	1	78	theme	starch	315:320	arg1	gels					360:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	mung bean starch (MBS)/flaxseed protein (FP) composite gels	305:363	The effects of Astragalus polysaccharide (APS) on rheological, textural, water-holding, and microstructural properties of mung bean starch (MBS)/flaxseed protein (FP) composite gels were investigated.					
37001775	6	79	theme	network	1350:1356	arg1	formation					1320:1328	the formation	1316:1328	the formation of strengthened gel network and the change of gel properties	1316:1389	Mechanistically, APS could influence the interactions between starch and protein within the tri-polymeric composite systems by affecting starch gelatinization and hydrogen bonding, further contributing to the formation of strengthened gel network and the change of gel properties.					
37001775	4	80	theme	pore	839:842	arg1	size					844:847	reduced pore size	831:847	reduced pore size	831:847	Microstructurally, the MBS/FP/APS composite gels displayed a complex network with reduced pore size compared with that of the control gel (MBS/FP).					
37001775	7	81	theme	systems	1525:1531	arg1	properties					1482:1491	the structural and textural properties	1454:1491	the structural and textural properties of the starch-protein composite systems	1454:1531	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
37001775	7	82	theme	composite	1515:1523	arg1	systems					1525:1531	the starch-protein composite systems	1496:1531	the starch-protein composite systems	1496:1531	These results suggest that the macromolecular APS can improve the structural and textural properties of the starch-protein composite systems, and impart various functional properties to the FP-based gel foods.					
36070358	1	0	theme	big	355:357	arg1	challenge					359:367	a big challenge	353:367	a big challenge	353:367	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	1	1	theme	smart	175:179	arg1	devices					190:196	smart wearable devices	175:196	smart wearable devices	175:196	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	1	2	theme	wearable	181:188	arg1	devices					190:196	smart wearable devices	175:196	smart wearable devices	175:196	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	3	theme	structural	558:567	arg1	colors					569:574	naked-eye-visible brilliant structural colors	530:574	naked-eye-visible brilliant structural colors	530:574	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	4	theme	vivid	267:271	arg1	coloration					284:293	vivid structural coloration	267:293	vivid structural coloration	267:293	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	5	theme	brilliant	548:556	arg1	colors					569:574	naked-eye-visible brilliant structural colors	530:574	naked-eye-visible brilliant structural colors	530:574	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	3	6	theme	smart	741:745	arg1	film					719:722	the film	715:722	the film	715:722	By adjusting the stretching, the film is designed as a smart skin to adapt to surrounding environments for camouflage.					
36070358	3	6	theme	smart	741:745	arg1	skin					747:750	a smart skin	739:750	a smart skin	739:750	By adjusting the stretching, the film is designed as a smart skin to adapt to surrounding environments for camouflage.					
36070358	2	7	theme	wavelength	629:638	arg1	region					640:645	a broad wavelength region	621:645	a broad wavelength region at a moderate deformation (like skin)	621:683	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	8	theme	structural	273:282	arg1	coloration					284:293	vivid structural coloration	267:293	vivid structural coloration	267:293	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	9	theme	naked-eye-visible	530:546	arg1	colors					569:574	naked-eye-visible brilliant structural colors	530:574	naked-eye-visible brilliant structural colors	530:574	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	4	10	theme	biomimic	860:867	arg1	skins					900:904	biomimic optically functional cellulose skins	860:904	biomimic optically functional cellulose skins	860:904	This work offers a universal strategy for constructing biomimic optically functional cellulose skins.					
36070358	1	11	theme	Recent	101:106	arg1	advances					108:115	Recent advances	101:115	Recent advances of photonic crystals	101:136	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	0	12	theme	Optical	12:18	arg1	Films					51:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	4	13	theme	cellulose	890:898	arg1	skins					900:904	biomimic optically functional cellulose skins	860:904	biomimic optically functional cellulose skins	860:904	This work offers a universal strategy for constructing biomimic optically functional cellulose skins.					
36070358	2	14	theme	ternary	388:394	arg1	co-assembly					396:406	a ternary co-assembly and post-UV-irradiation polymerization strategy	386:454	co-assembly	396:406	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	2	15	theme	moderate	652:659	arg1	deformation					661:671	a moderate deformation	650:671	a moderate deformation (like skin)	650:683	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	0	16	theme	Cellulose	29:37	arg1	Films					51:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	3	17	theme	surrounding	764:774	arg1	environments					776:787	surrounding environments	764:787	surrounding environments	764:787	By adjusting the stretching, the film is designed as a smart skin to adapt to surrounding environments for camouflage.					
36070358	2	18	theme	color	599:603	arg1	change					605:610	stretching-induced color change	580:610	stretching-induced color change	580:610	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	19	theme	photonic	120:127	arg1	crystals					129:136	photonic crystals	120:136	photonic crystals	120:136	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	0	20	theme	Flexible	20:27	arg1	Films					51:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	1	21	theme	reversible	299:308	arg1	mechanochromism					310:324	reversible mechanochromism	299:324	reversible mechanochromism like chameleon skin	299:344	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	22	theme	stretching-induced	580:597	arg1	change					605:610	stretching-induced color change	580:610	stretching-induced color change	580:610	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	23	theme	crystals	129:136	arg1	advances					108:115	Recent advances	101:115	Recent advances of photonic crystals	101:136	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	24	theme	composite	492:500	arg1	films					502:506	flexible and elastic CNC composite films	467:506	flexible and elastic CNC composite films	467:506	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	25	theme	chiral	212:217	arg1	materials					256:264	chiral photonic cellulose nanocrystal (CNC) materials	212:264	chiral photonic cellulose nanocrystal (CNC) materials	212:264	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	26	theme	polymerization	432:445	arg1	strategy					447:454	a ternary co-assembly and post-UV-irradiation polymerization strategy	386:454	strategy	447:454	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	27	theme	photonic	219:226	arg1	CNC					251:253	CNC	251:253	CNC	251:253	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	1	27	theme	photonic	219:226	arg1	nanocrystal					238:248	photonic cellulose nanocrystal	219:248	chiral photonic cellulose nanocrystal (CNC) materials	212:264	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	0	28	theme	Nanocrystal	39:49	arg1	Films					51:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Optical Flexible Cellulose Nanocrystal Films	12:55	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	2	29	from	deformation	661:671	arg1	region					640:645	a broad wavelength region	621:645	a broad wavelength region at a moderate deformation (like skin)	621:683	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	2	30	theme	flexible	467:474	arg1	films					502:506	flexible and elastic CNC composite films	467:506	flexible and elastic CNC composite films	467:506	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	31	theme	cellulose	228:236	arg1	CNC					251:253	CNC	251:253	CNC	251:253	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	1	31	theme	cellulose	228:236	arg1	nanocrystal					238:248	photonic cellulose nanocrystal	219:248	chiral photonic cellulose nanocrystal (CNC) materials	212:264	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	0	32	theme	Strain-Adaptive	62:76	arg1	Coloration					89:98	Strain-Adaptive Structural Coloration	62:98	Strain-Adaptive Structural Coloration	62:98	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	1	33	theme	chameleon	331:339	arg1	skin					341:344	chameleon skin	331:344	chameleon skin	331:344	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	34	theme	broad	623:627	arg1	region					640:645	a broad wavelength region	621:645	a broad wavelength region at a moderate deformation (like skin)	621:683	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	4	35	theme	functional	879:888	arg1	skins					900:904	biomimic optically functional cellulose skins	860:904	biomimic optically functional cellulose skins	860:904	This work offers a universal strategy for constructing biomimic optically functional cellulose skins.					
36070358	2	36	theme	CNC	488:490	arg1	films					502:506	flexible and elastic CNC composite films	467:506	flexible and elastic CNC composite films	467:506	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	4	37	theme	universal	824:832	arg1	strategy					834:841	a universal strategy	822:841	a universal strategy for constructing biomimic optically functional cellulose skins	822:904	This work offers a universal strategy for constructing biomimic optically functional cellulose skins.					
36070358	1	38	theme	nanocrystal	238:248	arg1	materials					256:264	chiral photonic cellulose nanocrystal (CNC) materials	212:264	chiral photonic cellulose nanocrystal (CNC) materials	212:264	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	39	contain	have	525:528	arg2	colors					569:574	naked-eye-visible brilliant structural colors	530:574	naked-eye-visible brilliant structural colors	530:574	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	2	39	contain	have	525:528	arg1	films					502:506	flexible and elastic CNC composite films	467:506	flexible and elastic CNC composite films	467:506	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	2	39	contain	have	525:528	arg2	change					605:610	stretching-induced color change	580:610	stretching-induced color change	580:610	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	1	40	theme	mechanical	152:161	arg1	sensors					163:169	mechanical sensors	152:169	mechanical sensors	152:169	Recent advances of photonic crystals are driven to mechanical sensors and smart wearable devices; however, for chiral photonic cellulose nanocrystal (CNC) materials, vivid structural coloration and reversible mechanochromism like chameleon skin remain a big challenge.					
36070358	2	41	theme	post-UV-irradiation	412:430	arg1	strategy					447:454	a ternary co-assembly and post-UV-irradiation polymerization strategy	386:454	strategy	447:454	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
36070358	0	42	theme	Structural	78:87	arg1	Coloration					89:98	Strain-Adaptive Structural Coloration	62:98	Strain-Adaptive Structural Coloration	62:98	Bioinspired Optical Flexible Cellulose Nanocrystal Films with Strain-Adaptive Structural Coloration.					
36070358	2	43	theme	elastic	480:486	arg1	films					502:506	flexible and elastic CNC composite films	467:506	flexible and elastic CNC composite films	467:506	Here, we report a ternary co-assembly and post-UV-irradiation polymerization strategy to develop flexible and elastic CNC composite films, which, notably, have naked-eye-visible brilliant structural colors and stretching-induced color change covering a broad wavelength region at a moderate deformation (like skin).					
37321007	0	0	theme	bone	86:89	arg1	repair					98:103	bone tissue repair	86:103	bone tissue repair	86:103	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	7	1	theme	recent	1373:1378	arg1	years					1380:1384	recent years	1373:1384	recent years	1373:1384	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	5	2	theme	bone	1086:1089	arg1	defects					1091:1097	bone defects	1086:1097	bone defects	1086:1097	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	5	3	theme	hydrogels	911:919	arg1	viscosity					876:884	the adjustable viscosity	861:884	the adjustable viscosity of sodium alginate-based hydrogels	861:919	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	0	4	from	Progress	0:7	arg1	application					16:26	the application	12:26	the application of 3D-printed sodium alginate-based hydrogel	12:71	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	4	5	theme	hydrogels	755:763	arg1	functionality					722:734	the functionality	718:734	the functionality of sodium alginate hydrogels	718:763	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	2	6	theme	comprehensive	278:290	arg1	properties					292:301	the excellent comprehensive properties	264:301	the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate	264:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	0	7	theme	tissue	91:96	arg1	repair					98:103	bone tissue repair	86:103	bone tissue repair	86:103	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	5	8	theme	defects	1091:1097	arg1	repair					1076:1081	the repair	1072:1081	the repair of bone defects	1072:1097	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	3	9	theme	properties	543:552	arg1	problems					497:504	the problems	493:504	the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels	493:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	6	10	theme	physical	1207:1214	arg1	blending					1216:1223	physical blending	1207:1223	physical blending	1207:1223	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	2	11	theme	excellent	268:276	arg1	properties					292:301	the excellent comprehensive properties	264:301	the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate	264:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	4	12	theme	sodium	739:744	arg1	hydrogels					755:763	sodium alginate hydrogels	739:763	sodium alginate hydrogels	739:763	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	2	13	theme	sodium	347:352	arg1	alginate					354:361	sodium alginate	347:361	sodium alginate	347:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	7	14	theme	tissue	1324:1329	arg1	repair					1331:1336	bone tissue repair	1319:1336	bone tissue repair based on 3D printing technology	1319:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	3	15	theme	adhesion	519:526	arg1	problems					497:504	the problems	493:504	the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels	493:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	4	16	theme	materials	691:699	arg1	blending					670:677	The composite blending	656:677	The composite blending of multiple materials	656:699	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	2	17	theme	researchers	401:411	arg1	attention					388:396	the great attention	378:396	the great attention of researchers	378:411	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	5	18	theme	sodium	922:927	arg1	hydrogels					944:952	sodium alginate-based hydrogels	922:952	sodium alginate-based hydrogels	922:952	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	6	19	theme	sodium	1165:1170	arg1	alginate					1172:1179	sodium alginate	1165:1179	sodium alginate	1165:1179	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	7	20	theme	3D	1347:1348	arg1	technology					1359:1368	3D printing technology	1347:1368	3D printing technology	1347:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	7	21	theme	scaffolds	1305:1313	arg1	progress					1262:1269	the application progress	1246:1269	the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years	1246:1384	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	2	22	theme	polymer	314:320	arg1	hydrogels					322:330	natural polymer hydrogels	306:330	natural polymer hydrogels represented by sodium alginate	306:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	7	23	theme	sodium	1274:1279	arg1	scaffolds					1305:1313	sodium alginate-based hydrogel scaffolds	1274:1313	sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology	1274:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	1	24	theme	biomedical	162:171	arg1	field					173:177	the biomedical field	158:177	the biomedical field	158:177	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	5	25	theme	adjustable	865:874	arg1	viscosity					876:884	the adjustable viscosity	861:884	the adjustable viscosity of sodium alginate-based hydrogels	861:919	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	2	26	theme	natural	306:312	arg1	hydrogels					322:330	natural polymer hydrogels	306:330	natural polymer hydrogels represented by sodium alginate	306:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	4	27	theme	composite	783:791	arg1	hydrogel					793:800	the prepared composite hydrogel	770:800	the prepared composite hydrogel	770:800	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	2	28	theme	great	382:386	arg1	attention					388:396	the great attention	378:396	the great attention of researchers	378:411	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	4	29	theme	application	820:830	arg1	field					832:836	a larger application field	811:836	a larger application field	811:836	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	7	30	from	progress	1262:1269	arg1	years					1380:1384	recent years	1373:1384	recent years	1373:1384	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	7	31	theme	bone	1319:1322	arg1	repair					1331:1336	bone tissue repair	1319:1336	bone tissue repair based on 3D printing technology	1319:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	3	32	theme	hydrogels	573:581	arg1	adhesion					519:526	poor cell adhesion	509:526	poor cell adhesion	509:526	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	3	32	theme	hydrogels	573:581	arg1	properties					543:552	mechanical properties	532:552	mechanical properties of sodium alginate hydrogels	532:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	6	33	theme	other	1185:1189	arg1	materials					1191:1199	other materials	1185:1199	other materials	1185:1199	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	6	34	theme	alginate	1172:1179	arg1	properties					1151:1160	the properties	1147:1160	the properties of sodium alginate and other materials	1147:1199	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	6	35	theme	materials	1191:1199	arg1	properties					1151:1160	the properties	1147:1160	the properties of sodium alginate and other materials	1147:1199	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	3	36	theme	sodium	557:562	arg1	hydrogels					573:581	sodium alginate hydrogels	557:581	sodium alginate hydrogels	557:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	5	37	theme	biological	990:999	arg1	ink					1001:1003	biological ink	990:1003	biological ink	990:1003	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	0	38	theme	3D-printed	31:40	arg1	hydrogel					64:71	3D-printed sodium alginate-based hydrogel	31:71	3D-printed sodium alginate-based hydrogel	31:71	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	7	39	theme	application	1250:1260	arg1	progress					1262:1269	the application progress	1246:1269	the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years	1246:1384	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	4	40	theme	multiple	682:689	arg1	materials					691:699	multiple materials	682:699	multiple materials	682:699	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	4	41	theme	composite	660:668	arg1	blending					670:677	The composite blending	656:677	The composite blending of multiple materials	656:699	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	3	42	theme	same	421:424	arg1	time					426:429	the same time	417:429	the same time	417:429	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	1	43	with	materials	182:190	arg1	structures					214:223	excellent bionic structures	197:223	excellent bionic structures	197:223	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	1	43	with	materials	182:190	arg1	properties					240:249	biological properties	229:249	biological properties	229:249	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	3	44	theme	alginate	646:653	arg1	modification					623:634	chemical modification	614:634	chemical modification of sodium alginate	614:653	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	6	45	theme	properties	1151:1160	arg1	improvement					1132:1142	the improvement	1128:1142	the improvement of the properties of sodium alginate and other materials after physical blending	1128:1223	This paper first summarizes the improvement of the properties of sodium alginate and other materials after physical blending.					
37321007	8	46	theme	theoretical	1452:1462	arg1	basis					1464:1468	a theoretical basis	1450:1468	a theoretical basis for follow-up research	1450:1491	Moreover, we provide relevant opinions and comments to provide a theoretical basis for follow-up research.					
37321007	1	47	theme	excellent	197:205	arg1	structures					214:223	excellent bionic structures	197:223	excellent bionic structures	197:223	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	0	48	theme	alginate-based	49:62	arg1	hydrogel					64:71	3D-printed sodium alginate-based hydrogel	31:71	3D-printed sodium alginate-based hydrogel	31:71	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	5	49	theme	alginate-based	896:909	arg1	hydrogels					911:919	sodium alginate-based hydrogels	889:919	sodium alginate-based hydrogels	889:919	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	7	50	theme	printing	1350:1357	arg1	technology					1359:1368	3D printing technology	1347:1368	3D printing technology	1347:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	4	51	theme	prepared	774:781	arg1	hydrogel					793:800	the prepared composite hydrogel	770:800	the prepared composite hydrogel	770:800	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	3	52	theme	sodium	639:644	arg1	alginate					646:653	sodium alginate	639:653	sodium alginate	639:653	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	1	53	theme	recent	109:114	arg1	years					116:120	recent years	109:120	recent years	109:120	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	0	54	theme	sodium	42:47	arg1	hydrogel					64:71	3D-printed sodium alginate-based hydrogel	31:71	3D-printed sodium alginate-based hydrogel	31:71	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	5	55	theme	3D	1045:1046	arg1	technology					1057:1066	3D printing technology	1045:1066	3D printing technology for the repair of bone defects	1045:1097	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	8	56	theme	follow-up	1474:1482	arg1	research					1484:1491	follow-up research	1474:1491	follow-up research	1474:1491	Moreover, we provide relevant opinions and comments to provide a theoretical basis for follow-up research.					
37321007	7	57	theme	alginate-based	1281:1294	arg1	scaffolds					1305:1313	sodium alginate-based hydrogel scaffolds	1274:1313	sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology	1274:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	7	58	theme	hydrogel	1296:1303	arg1	scaffolds					1305:1313	sodium alginate-based hydrogel scaffolds	1274:1313	sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology	1274:1368	Then, it summarizes the application progress of sodium alginate-based hydrogel scaffolds for bone tissue repair based on 3D printing technology in recent years.					
37321007	3	59	theme	alginate	564:571	arg1	hydrogels					573:581	sodium alginate hydrogels	557:581	sodium alginate hydrogels	557:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	5	60	theme	printing	1048:1055	arg1	technology					1057:1066	3D printing technology	1045:1066	3D printing technology for the repair of bone defects	1045:1097	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	3	61	theme	other	476:480	arg1	materials					482:490	other materials	476:490	other materials	476:490	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	5	62	theme	sodium	889:894	arg1	hydrogels					911:919	sodium alginate-based hydrogels	889:919	sodium alginate-based hydrogels	889:919	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	1	63	theme	bionic	207:212	arg1	structures					214:223	excellent bionic structures	197:223	excellent bionic structures	197:223	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	5	64	theme	alginate-based	929:942	arg1	hydrogels					944:952	sodium alginate-based hydrogels	922:952	sodium alginate-based hydrogels	922:952	In addition, based on the adjustable viscosity of sodium alginate-based hydrogels, sodium alginate-based hydrogels can be loaded with cells to prepare biological ink, and the scaffold can be printed out by 3D printing technology for the repair of bone defects.					
37321007	1	65	used	used	150:153	arg2	materials					182:190	materials	182:190	materials with excellent bionic structures and biological properties	182:249	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	1	65	used	used	150:153	arg2	hydrogels					123:131	hydrogels	123:131	hydrogels	123:131	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
37321007	2	66	theme	hydrogels	322:330	arg1	properties					292:301	the excellent comprehensive properties	264:301	the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate	264:361	Among them, the excellent comprehensive properties of natural polymer hydrogels represented by sodium alginate have attracted the great attention of researchers.					
37321007	4	67	theme	alginate	746:753	arg1	hydrogels					755:763	sodium alginate hydrogels	739:763	sodium alginate hydrogels	739:763	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	3	68	theme	sodium	455:460	arg1	alginate					462:469	sodium alginate	455:469	sodium alginate	455:469	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	3	69	theme	chemical	614:621	arg1	modification					623:634	chemical modification	614:634	chemical modification of sodium alginate	614:653	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	3	70	theme	poor	509:512	arg1	adhesion					519:526	poor cell adhesion	509:526	poor cell adhesion	509:526	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	4	71	contain	has	807:809	arg1	hydrogel					793:800	the prepared composite hydrogel	770:800	the prepared composite hydrogel	770:800	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	4	71	contain	has	807:809	arg2	field					832:836	a larger application field	811:836	a larger application field	811:836	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	0	72	theme	hydrogel	64:71	arg1	application					16:26	the application	12:26	the application of 3D-printed sodium alginate-based hydrogel	12:71	Progress in the application of 3D-printed sodium alginate-based hydrogel scaffolds in bone tissue repair.					
37321007	3	73	theme	mechanical	532:541	arg1	properties					543:552	mechanical properties	532:552	mechanical properties of sodium alginate hydrogels	532:581	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	4	74	theme	larger	813:818	arg1	field					832:836	a larger application field	811:836	a larger application field	811:836	The composite blending of multiple materials can also improve the functionality of sodium alginate hydrogels, and the prepared composite hydrogel also has a larger application field.					
37321007	3	75	theme	cell	514:517	arg1	adhesion					519:526	poor cell adhesion	509:526	poor cell adhesion	509:526	At the same time, by physically blending sodium alginate with other materials, the problems of poor cell adhesion and mechanical properties of sodium alginate hydrogels were directly improved without chemical modification of sodium alginate.					
37321007	8	76	theme	relevant	1408:1415	arg1	opinions					1417:1424	relevant opinions	1408:1424	relevant opinions	1408:1424	Moreover, we provide relevant opinions and comments to provide a theoretical basis for follow-up research.					
37321007	1	77	theme	biological	229:238	arg1	properties					240:249	biological properties	229:249	biological properties	229:249	In recent years, hydrogels have been widely used in the biomedical field as materials with excellent bionic structures and biological properties.					
35725210	0	0	with	electrodes	47:56	arg1	capacitance					74:84	high areal capacitance	63:84	high areal capacitance	63:84	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	1	1	theme	composite	159:167	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	1	theme	composite	159:167	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	0	2	theme	flexible	90:97	arg1	supercapacitors					99:113	flexible supercapacitors	90:113	flexible supercapacitors	90:113	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	4	3	theme	bent	895:898	arg1	states					900:905	different bent states	885:905	different bent states	885:905	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	5	4	theme	impressive	925:934	arg1	potential					936:944	impressive potential	925:944	impressive potential	925:944	This study shows impressive potential in fabricating high-performance electrodes for flexible supercapacitors.					
35725210	3	5	from	density	523:529	arg1	5.0 mA cm-2					593:603	5.0 mA cm-2	593:603	5.0 mA cm-2	593:603	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	6	theme	efficient	293:301	arg1	approach					331:338	a facile and efficient electrostatic self-assembly approach	280:338	a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	280:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	4	7	theme	PPy	774:776	arg1	electrodes					782:791	the PPy@SBC electrodes	770:791	the PPy@SBC electrodes	770:791	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	3	8	theme	capacitance	559:569	arg1	retention					571:579	a desirable capacitance retention	547:579	a desirable capacitance retention of 83.1% at 5.0 mA cm-2	547:603	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	9	dep	stability	627:635	arg1	retention					652:660	a capacitance retention	638:660	a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2	638:703	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	10	theme	facile	282:287	arg1	approach					331:338	a facile and efficient electrostatic self-assembly approach	280:338	a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	280:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	3	11	theme	@	444:444	arg1	electrode					449:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	12	theme	obtained	432:439	arg1	electrode					449:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	4	13	theme	SBC	778:780	arg1	electrodes					782:791	the PPy@SBC electrodes	770:791	the PPy@SBC electrodes	770:791	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	3	14	theme	0.5 mA cm-2	534:544	arg1	density					523:529	a current density	513:529	a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	513:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	4	15	theme	different	885:893	arg1	states					900:905	different bent states	885:905	different bent states	885:905	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	1	16	theme	promising	185:193	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	16	theme	promising	185:193	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	3	17	from	10 mA cm-2	694:703	arg1	10,000 cycles					677:689	10,000 cycles	677:689	10,000 cycles at 10 mA cm-2	677:703	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	18	theme	%	588:588	arg1	stability					627:635	excellent cycling stability	609:635	excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	609:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	18	theme	%	588:588	arg1	retention					571:579	a desirable capacitance retention	547:579	a desirable capacitance retention of 83.1% at 5.0 mA cm-2	547:603	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	18	theme	%	588:588	arg1	0.5 mA cm-2					534:544	0.5 mA cm-2	534:544	0.5 mA cm-2	534:544	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	4	19	theme	@	777:777	arg1	electrodes					782:791	the PPy@SBC electrodes	770:791	the PPy@SBC electrodes	770:791	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	3	20	theme	SBC	445:447	arg1	electrode					449:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	0	21	theme	cellulose	37:45	arg1	electrodes					47:56	bacterial cellulose electrodes	27:56	bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors	27:113	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	4	22	theme	outstanding	810:820	arg1	flexibility					833:843	outstanding mechanical flexibility	810:843	outstanding mechanical flexibility	810:843	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	2	23	theme	self-assembly	317:329	arg1	approach					331:338	a facile and efficient electrostatic self-assembly approach	280:338	a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	280:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	3	24	from	5.0 mA cm-2	593:603	arg1	density					523:529	a current density	513:529	a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	513:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	24	from	5.0 mA cm-2	593:603	arg1	stability					627:635	excellent cycling stability	609:635	excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	609:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	24	from	5.0 mA cm-2	593:603	arg1	retention					571:579	a desirable capacitance retention	547:579	a desirable capacitance retention of 83.1% at 5.0 mA cm-2	547:603	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	24	from	5.0 mA cm-2	593:603	arg1	0.5 mA cm-2					534:544	0.5 mA cm-2	534:544	0.5 mA cm-2	534:544	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	25	theme	areal	476:480	arg1	capacitance					482:492	a high areal capacitance	469:492	a high areal capacitance of 5718 mF cm-2	469:508	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	0	26	theme	bacterial	27:35	arg1	electrodes					47:56	bacterial cellulose electrodes	27:56	bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors	27:113	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	5	27	theme	flexible	993:1000	arg1	supercapacitors					1002:1016	flexible supercapacitors	993:1016	flexible supercapacitors	993:1016	This study shows impressive potential in fabricating high-performance electrodes for flexible supercapacitors.					
35725210	2	28	theme	electrostatic	303:315	arg1	approach					331:338	a facile and efficient electrostatic self-assembly approach	280:338	a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	280:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	1	29	theme	lightweight	203:213	arg1	electrodes					228:237	lightweight and flexible electrodes	203:237	lightweight and flexible electrodes for supercapacitors	203:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	3	30	theme	current	515:521	arg1	density					523:529	a current density	513:529	a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	513:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	31	theme	anion-doped	364:374	arg1	PPy					376:378	uniformly depositing anion-doped PPy	343:378	uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	343:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	3	32	theme	PPy	441:443	arg1	electrode					449:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode	428:457	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	33	theme	capacitance	640:650	arg1	retention					652:660	a capacitance retention	638:660	a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2	638:703	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	34	theme	excellent	609:617	arg1	stability					627:635	excellent cycling stability	609:635	excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	609:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	1	35	theme	flexible	219:226	arg1	electrodes					228:237	lightweight and flexible electrodes	203:237	lightweight and flexible electrodes for supercapacitors	203:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	0	36	theme	areal	68:72	arg1	capacitance					74:84	high areal capacitance	63:84	high areal capacitance	63:84	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	4	37	theme	negligible	850:859	arg1	decay					873:877	negligible capacitance decay	850:877	negligible capacitance decay under different bent states	850:905	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	4	38	theme	flexible	719:726	arg1	supercapacitor					728:741	A symmetric flexible supercapacitor	707:741	A symmetric flexible supercapacitor	707:741	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	0	39	theme	high	63:66	arg1	capacitance					74:84	high areal capacitance	63:84	high areal capacitance	63:84	Polypyrrole/SnCl2 modified bacterial cellulose electrodes with high areal capacitance for flexible supercapacitors.					
35725210	4	40	theme	capacitance	861:871	arg1	decay					873:877	negligible capacitance decay	850:877	negligible capacitance decay under different bent states	850:905	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	1	41	theme	/bacterial	133:142	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	41	theme	/bacterial	133:142	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	42	theme	BC	155:156	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	42	theme	BC	155:156	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	4	43	theme	mechanical	822:831	arg1	flexibility					833:843	outstanding mechanical flexibility	810:843	outstanding mechanical flexibility	810:843	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
35725210	1	44	theme	cellulose	144:152	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	44	theme	cellulose	144:152	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	3	45	theme	retention	571:579	arg1	density					523:529	a current density	513:529	a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	513:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	1	46	theme	electrodes	228:237	arg1	kind					195:198	a promising kind	183:198	a promising kind of lightweight and flexible electrodes for supercapacitors	183:257	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	1	46	theme	electrodes	228:237	arg1	membranes					169:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes	116:177	Polypyrrole (PPy)/bacterial cellulose (BC) composite membranes are a promising kind of lightweight and flexible electrodes for supercapacitors.					
35725210	5	47	theme	high-performance	961:976	arg1	electrodes					978:987	high-performance electrodes	961:987	high-performance electrodes for flexible supercapacitors	961:1016	This study shows impressive potential in fabricating high-performance electrodes for flexible supercapacitors.					
35725210	3	48	theme	%	669:669	arg1	retention					652:660	a capacitance retention	638:660	a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2	638:703	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	49	theme	desirable	549:557	arg1	retention					571:579	a desirable capacitance retention	547:579	a desirable capacitance retention of 83.1% at 5.0 mA cm-2	547:603	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	50	theme	5718 mF cm-2	497:508	arg1	capacitance					482:492	a high areal capacitance	469:492	a high areal capacitance of 5718 mF cm-2	469:508	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	51	theme	depositing	353:362	arg1	PPy					376:378	uniformly depositing anion-doped PPy	343:378	uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC)	343:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	3	52	theme	high	471:474	arg1	capacitance					482:492	a high areal capacitance	469:492	a high areal capacitance of 5718 mF cm-2	469:508	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	3	53	theme	cycling	619:625	arg1	stability					627:635	excellent cycling stability	609:635	excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	609:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	54	theme	SnCl2-modifed	404:416	arg1	SBC					422:424	SBC	422:424	SBC	422:424	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	2	54	theme	SnCl2-modifed	404:416	arg1	BC					418:419	positively charged SnCl2-modifed BC	385:419	positively charged SnCl2-modifed BC (SBC)	385:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	3	55	theme	stability	627:635	arg1	density					523:529	a current density	513:529	a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2)	513:704	The obtained PPy@SBC electrode exhibited a high areal capacitance of 5718 mF cm-2 at a current density of 0.5 mA cm-2, a desirable capacitance retention of 83.1% at 5.0 mA cm-2 and excellent cycling stability (a capacitance retention of 86.8% after 10,000 cycles at 10 mA cm-2).					
35725210	2	56	theme	charged	396:402	arg1	SBC					422:424	SBC	422:424	SBC	422:424	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	2	56	theme	charged	396:402	arg1	BC					418:419	positively charged SnCl2-modifed BC	385:419	positively charged SnCl2-modifed BC (SBC)	385:425	Herein, we explored a facile and efficient electrostatic self-assembly approach to uniformly depositing anion-doped PPy onto positively charged SnCl2-modifed BC (SBC).					
35725210	4	57	theme	symmetric	709:717	arg1	supercapacitor					728:741	A symmetric flexible supercapacitor	707:741	A symmetric flexible supercapacitor	707:741	A symmetric flexible supercapacitor was further assembled with the PPy@SBC electrodes, which delivered outstanding mechanical flexibility with negligible capacitance decay under different bent states.					
36587130	1	0	gly	glycoproteins	162:174	arg1	scaffold					117:124	a molecular scaffold	105:124	a molecular scaffold mainly comprising fibrous proteins	105:159	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	0	gly	glycoproteins	162:174	arg1	glycoproteins					162:174	glycoproteins	162:174	glycoproteins	162:174	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	4	1	from	role	728:731	arg1	cancer					754:759	breast cancer	747:759	breast cancer	747:759	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	1	2	theme	fibrous	144:150	arg1	proteins					152:159	fibrous proteins	144:159	fibrous proteins	144:159	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	5	3	theme	enrichment	894:903	arg1	analysis					922:929	the enrichment and quantitative analysis	890:929	not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling	819:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	3	4	theme	deposition	473:482	arg1	dysregulation					452:464	dysregulation	452:464	dysregulation of its deposition and remodelling	452:498	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	5	5	theme	modified	955:962	arg1	peptides					964:971	post-translationally modified peptides	934:971	post-translationally modified peptides	934:971	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	3	6	theme	tumor	526:530	arg1	onset					532:536	tumor onset	526:536	tumor onset	526:536	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	5	7	theme	quantitative	909:920	arg1	analysis					922:929	the enrichment and quantitative analysis	890:929	not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling	819:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	4	8	theme	downstream	697:706	arg1	assays					708:713	downstream assays	697:713	downstream assays studying the role of the ECM in breast cancer	697:759	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	5	9	theme	expression	863:872	arg1	quantitation					839:850	the global quantitation	828:850	not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling	819:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	4	10	theme	ECM	663:665	arg1	analysis					647:654	subsequent proteomic analysis	626:654	subsequent proteomic analysis	626:654	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	4	10	theme	ECM	663:665	arg1	isolation					612:620	isolation	612:620	isolation	612:620	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	5	11	theme	protein	855:861	arg1	expression					863:872	protein expression	855:872	protein expression	855:872	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	5	12	theme	protein	793:799	arg1	amounts					801:807	sufficient protein amounts	782:807	sufficient protein amounts	782:807	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	5	13	theme	global	832:837	arg1	quantitation					839:850	the global quantitation	828:850	not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling	819:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	1	14	theme	extracellular	75:87	arg1	scaffold					117:124	a molecular scaffold	105:124	a molecular scaffold mainly comprising fibrous proteins	105:159	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	14	theme	extracellular	75:87	arg1	ECM					97:99	ECM	97:99	ECM	97:99	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	14	theme	extracellular	75:87	arg1	matrix					89:94	The extracellular matrix	71:94	The extracellular matrix (ECM)	71:100	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	3	15	theme	cancer	372:377	arg1	context					361:367	the context	357:367	the context of cancer	357:377	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	5	16	theme	peptides	964:971	arg1	analysis					922:929	the enrichment and quantitative analysis	890:929	not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling	819:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	4	17	theme	glands	685:690	arg1	ECM					663:665	the ECM	659:665	the ECM of murine mammary glands	659:690	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	3	18	theme	critical	393:400	arg1	ECM					384:386	the ECM	380:386	the ECM	380:386	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	3	18	theme	critical	393:400	arg1	component					402:410	a critical component	391:410	a critical component of the tumor microenvironment (TME)	391:446	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	0	19	theme	Proteomic	0:8	arg1	Assessment					10:19	Proteomic Assessment	0:19	Proteomic Assessment of the Murine Mammary Gland	0:47	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	4	20	theme	mammary	677:683	arg1	glands					685:690	murine mammary glands	670:690	murine mammary glands	670:690	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	4	21	theme	ECM	740:742	arg1	role					728:731	the role	724:731	the role of the ECM in breast cancer	724:759	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	2	22	theme	cell-matrix	287:297	arg1	interactions					299:310	cell-matrix interactions	287:310	cell-matrix interactions	287:310	Aside from acting as a structural support, the ECM's composition dictates cell-matrix interactions at the biochemical and biophysical level.					
36587130	0	23	dep	Matrix	63:68	arg1	Assessment					10:19	Proteomic Assessment	0:19	Proteomic Assessment of the Murine Mammary Gland	0:47	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	0	24	theme	Mammary	35:41	arg1	Gland					43:47	the Murine Mammary Gland	24:47	the Murine Mammary Gland	24:47	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	4	25	theme	breast	747:752	arg1	cancer					754:759	breast cancer	747:759	breast cancer	747:759	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	3	26	theme	tumor	419:423	arg1	microenvironment					425:440	the tumor microenvironment	415:440	the tumor microenvironment (TME)	415:446	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	3	26	theme	tumor	419:423	arg1	TME					443:445	TME	443:445	TME	443:445	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	0	27	theme	Murine	28:33	arg1	Gland					43:47	the Murine Mammary Gland	24:47	the Murine Mammary Gland	24:47	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	5	28	theme	aberrant	982:989	arg1	signalling					991:1000	aberrant signalling	982:1000	aberrant signalling	982:1000	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	5	29	theme	sufficient	782:791	arg1	amounts					801:807	sufficient protein amounts	782:807	sufficient protein amounts	782:807	The protocol yields sufficient protein amounts to enable not only the global quantitation of protein expression but furthermore the enrichment and quantitative analysis of post-translationally modified peptides to study aberrant signalling.					
36587130	3	30	theme	microenvironment	425:440	arg1	ECM					384:386	the ECM	380:386	the ECM	380:386	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	3	30	theme	microenvironment	425:440	arg1	component					402:410	a critical component	391:410	a critical component of the tumor microenvironment (TME)	391:446	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	0	31	theme	Extracellular	49:61	arg1	Matrix					63:68	Extracellular Matrix	49:68	Extracellular Matrix	49:68	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	2	32	theme	biophysical	335:345	arg1	level					347:351	the biochemical and biophysical level	315:351	the biochemical and biophysical level	315:351	Aside from acting as a structural support, the ECM's composition dictates cell-matrix interactions at the biochemical and biophysical level.					
36587130	0	33	theme	Gland	43:47	arg1	Assessment					10:19	Proteomic Assessment	0:19	Proteomic Assessment of the Murine Mammary Gland	0:47	Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix.					
36587130	4	34	theme	murine	670:675	arg1	glands					685:690	murine mammary glands	670:690	murine mammary glands	670:690	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	1	35	theme	molecular	107:115	arg1	scaffold					117:124	a molecular scaffold	105:124	a molecular scaffold mainly comprising fibrous proteins	105:159	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	35	theme	molecular	107:115	arg1	polysaccharides					196:210	polysaccharides	196:210	polysaccharides	196:210	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	35	theme	molecular	107:115	arg1	glycoproteins					162:174	glycoproteins	162:174	glycoproteins	162:174	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	35	theme	molecular	107:115	arg1	matrix					89:94	The extracellular matrix	71:94	The extracellular matrix (ECM)	71:100	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	1	35	theme	molecular	107:115	arg1	proteoglycans					177:189	proteoglycans	177:189	proteoglycans	177:189	The extracellular matrix (ECM) is a molecular scaffold mainly comprising fibrous proteins, glycoproteins, proteoglycans, and polysaccharides.					
36587130	4	36	dep	isolation	612:620	arg1	the					608:610	the	608:610	the	608:610	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	4	37	theme	subsequent	626:635	arg1	analysis					647:654	subsequent proteomic analysis	626:654	subsequent proteomic analysis	626:654	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	2	38	theme	biochemical	319:329	arg1	level					347:351	the biochemical and biophysical level	315:351	the biochemical and biophysical level	315:351	Aside from acting as a structural support, the ECM's composition dictates cell-matrix interactions at the biochemical and biophysical level.					
36587130	4	39	theme	robust	588:593	arg1	protocol					595:602	a robust protocol	586:602	a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands	586:690	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	2	40	theme	structural	236:245	arg1	support					247:253	a structural support	234:253	a structural support	234:253	Aside from acting as a structural support, the ECM's composition dictates cell-matrix interactions at the biochemical and biophysical level.					
36587130	3	41	from	component	402:410	arg1	context					361:367	the context	357:367	the context of cancer	357:377	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36587130	4	42	theme	proteomic	637:645	arg1	analysis					647:654	subsequent proteomic analysis	626:654	subsequent proteomic analysis	626:654	Here, we describe a robust protocol for the isolation and subsequent proteomic analysis of the ECM of murine mammary glands, for downstream assays studying the role of the ECM in breast cancer.					
36587130	3	43	theme	remodelling	488:498	arg1	dysregulation					452:464	dysregulation	452:464	dysregulation of its deposition and remodelling	452:498	In the context of cancer, the ECM is a critical component of the tumor microenvironment (TME) and dysregulation of its deposition and remodelling has been shown to promote tumor onset, progression, and metastasis.					
36615281	2	0	theme	phosphates	547:556	arg1	formation					517:525	the formation	513:525	the formation of biphasic calcium phosphates	513:556	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	6	1	from	differentiation	1081:1095	arg1	microspheres					1127:1138	BCP-WFA-ALG microspheres	1115:1138	BCP-WFA-ALG microspheres	1115:1138	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	2	theme	calcium	539:545	arg1	phosphates					547:556	biphasic calcium phosphates	530:556	biphasic calcium phosphates	530:556	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	4	3	theme	BCP	910:912	arg1	microspheres					914:925	the pure BCP microspheres	901:925	the pure BCP microspheres	901:925	The water uptake into BCP-WFA-ALG microspheres was significantly higher than in the pure BCP microspheres.					
36615281	2	4	theme	A	395:395	arg1	microspheres					464:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres	378:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres	378:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	0	5	theme	Antibacterial	128:140	arg1	Activity					142:149	Antibacterial Activity	128:149	Antibacterial Activity	128:149	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	6	6	theme	BCP-WFA-ALG	1220:1230	arg1	microspheres					1242:1253	the BCP-WFA-ALG composite microspheres	1216:1253	the BCP-WFA-ALG composite microspheres	1216:1253	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	1	7	from	efficacy	341:348	arg1	applications					364:375	biomedical applications	353:375	biomedical applications	353:375	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	3	8	theme	TSDC	613:616	arg1	measurement					618:628	the TSDC measurement	609:628	the TSDC measurement of the BCP-WFA-ALG microspheres	609:660	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	5	9	theme	significant	970:980	arg1	enhancement					982:992	a significant enhancement	968:992	a significant enhancement in cell proliferation rate	968:1019	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	2	10	theme	X-ray	575:579	arg1	diffraction					581:591	X-ray diffraction	575:591	X-ray diffraction study	575:597	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	3	11	theme	control	778:784	arg1	microspheres					790:801	the control BCP microspheres	774:801	the control BCP microspheres in all the media	774:818	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	6	12	theme	increased	1153:1161	arg1	expression					1163:1172	an increased expression	1150:1172	an increased expression of osteogenic marker genes	1150:1199	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	13	theme	biphasic	530:537	arg1	phosphates					547:556	biphasic calcium phosphates	530:556	biphasic calcium phosphates	530:556	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	5	14	theme	BCP-WFA-ALG	1030:1040	arg1	microspheres					1052:1063	the BCP-WFA-ALG composite microspheres	1026:1063	the BCP-WFA-ALG composite microspheres	1026:1063	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	0	15	theme	Polarized	13:21	arg1	A					34:34	Electrically Polarized Withaferin A	0:34	Electrically Polarized Withaferin A	0:34	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	4	16	theme	pure	905:908	arg1	microspheres					914:925	the pure BCP microspheres	901:925	the pure BCP microspheres	901:925	The water uptake into BCP-WFA-ALG microspheres was significantly higher than in the pure BCP microspheres.					
36615281	6	17	theme	composite	1232:1240	arg1	microspheres					1242:1253	the BCP-WFA-ALG composite microspheres	1216:1253	the BCP-WFA-ALG composite microspheres	1216:1253	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	18	theme	phosphate	440:448	arg1	microspheres					464:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres	378:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres	378:475	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	3	19	theme	BCP-WFA-ALG	637:647	arg1	microspheres					649:660	the BCP-WFA-ALG microspheres	633:660	the BCP-WFA-ALG microspheres	633:660	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	2	20	theme	calcium	432:438	arg1	BCP-WFA-ALG					451:461	BCP-WFA-ALG	451:461	BCP-WFA-ALG	451:461	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	2	20	theme	calcium	432:438	arg1	phosphate					440:448	alginate-incorporated biphasic calcium phosphate	401:448	alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG)	401:462	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	4	21	theme	BCP-WFA-ALG	843:853	arg1	microspheres					855:866	BCP-WFA-ALG microspheres	843:866	BCP-WFA-ALG microspheres	843:866	The water uptake into BCP-WFA-ALG microspheres was significantly higher than in the pure BCP microspheres.					
36615281	5	22	theme	cell	997:1000	arg1	rate					1016:1019	cell proliferation rate	997:1019	cell proliferation rate	997:1019	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	1	23	theme	oil	234:236	arg1	method					247:252	oil emulsion method	234:252	oil emulsion method	234:252	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	0	24	theme	Withaferin	23:32	arg1	A					34:34	Electrically Polarized Withaferin A	0:34	Electrically Polarized Withaferin A	0:34	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	3	25	theme	BCP	786:788	arg1	microspheres					790:801	the control BCP microspheres	774:801	the control BCP microspheres in all the media	774:818	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	2	26	theme	biphasic	423:430	arg1	BCP-WFA-ALG					451:461	BCP-WFA-ALG	451:461	BCP-WFA-ALG	451:461	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	2	26	theme	biphasic	423:430	arg1	phosphate					440:448	alginate-incorporated biphasic calcium phosphate	401:448	alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG)	401:462	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	5	27	theme	proliferation	1002:1014	arg1	rate					1016:1019	cell proliferation rate	997:1019	cell proliferation rate	997:1019	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	1	28	theme	emulsion	238:245	arg1	method					247:252	oil emulsion method	234:252	oil emulsion method	234:252	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	0	29	theme	Alginate-Incorporated	40:60	arg1	Microspheres					89:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	3	30	theme	contact	717:723	arg1	lower					763:767	lower	763:767	lower	763:767	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	3	30	theme	contact	717:723	arg1	angle					725:729	the contact angle	713:729	the contact angle of the specimen	713:745	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	5	31	theme	MTT	928:930	arg1	results					938:944	MTT assay results	928:944	MTT assay results	928:944	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	6	32	theme	cells	1106:1110	arg1	differentiation					1081:1095	The osteogenic differentiation	1066:1095	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres	1066:1138	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	33	dep	diffraction	581:591	arg1	study					593:597	study	593:597	study	593:597	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	3	34	theme	nA/cm2	705:710	arg1	density					689:695	the highest current density	669:695	the highest current density of 5.37 nA/cm2	669:710	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	3	35	theme	highest	673:679	arg1	density					689:695	the highest current density	669:695	the highest current density of 5.37 nA/cm2	669:710	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	0	36	theme	Calcium	71:77	arg1	Microspheres					89:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	5	37	theme	assay	932:936	arg1	results					938:944	MTT assay results	928:944	MTT assay results	928:944	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	3	38	theme	microspheres	649:660	arg1	measurement					618:628	the TSDC measurement	609:628	the TSDC measurement of the BCP-WFA-ALG microspheres	609:660	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	6	39	theme	marker	1188:1193	arg1	genes					1195:1199	osteogenic marker genes	1177:1199	osteogenic marker genes	1177:1199	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	40	theme	withaferin	384:393	arg1	A					395:395	withaferin A	384:395	withaferin A	384:395	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	0	41	theme	Biphasic	62:69	arg1	Microspheres					89:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	3	42	from	microspheres	790:801	arg1	media					814:818	all the media	806:818	all the media	806:818	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	1	43	theme	biomedical	353:362	arg1	applications					364:375	biomedical applications	353:375	biomedical applications	353:375	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	3	44	theme	specimen	738:745	arg1	lower					763:767	lower	763:767	lower	763:767	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	3	44	theme	specimen	738:745	arg1	angle					725:729	the contact angle	713:729	the contact angle of the specimen	713:745	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	5	45	theme	composite	1042:1050	arg1	microspheres					1052:1063	the BCP-WFA-ALG composite microspheres	1026:1063	the BCP-WFA-ALG composite microspheres	1026:1063	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	1	46	theme	Biphasic	161:168	arg1	microspheres					188:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	6	47	theme	genes	1195:1199	arg1	expression					1163:1172	an increased expression	1150:1172	an increased expression of osteogenic marker genes	1150:1199	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	6	48	theme	MG	1100:1101	arg1	cells					1106:1110	MG 63 cells	1100:1110	MG 63 cells	1100:1110	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	6	49	theme	microspheres	1242:1253	arg1	case					1208:1211	the case	1204:1211	the case of the BCP-WFA-ALG composite microspheres	1204:1253	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	4	50	theme	water	825:829	arg1	uptake					831:836	The water uptake	821:836	The water uptake into BCP-WFA-ALG microspheres	821:866	The water uptake into BCP-WFA-ALG microspheres was significantly higher than in the pure BCP microspheres.					
36615281	4	50	theme	water	825:829	arg1	higher					886:891	higher	886:891	higher	886:891	The water uptake into BCP-WFA-ALG microspheres was significantly higher than in the pure BCP microspheres.					
36615281	1	51	theme	calcium	170:176	arg1	microspheres					188:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	5	52	from	enhancement	982:992	arg1	rate					1016:1019	cell proliferation rate	997:1019	cell proliferation rate	997:1019	MTT assay results showed that there was a significant enhancement in cell proliferation rate with the BCP-WFA-ALG composite microspheres.					
36615281	6	53	theme	osteogenic	1177:1186	arg1	genes					1195:1199	osteogenic marker genes	1177:1199	osteogenic marker genes	1177:1199	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	3	54	theme	current	681:687	arg1	density					689:695	the highest current density	669:695	the highest current density of 5.37 nA/cm2	669:710	Although the TSDC measurement of the BCP-WFA-ALG microspheres showed the highest current density of 5.37 nA/cm2, the contact angle of the specimen was found to be lower than the control BCP microspheres in all the media.					
36615281	6	55	theme	BCP-WFA-ALG	1115:1125	arg1	microspheres					1127:1138	BCP-WFA-ALG microspheres	1115:1138	BCP-WFA-ALG microspheres	1115:1138	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	1	56	theme	phosphate	178:186	arg1	microspheres					188:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres	161:199	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
36615281	0	57	theme	Phosphate	79:87	arg1	Microspheres					89:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Alginate-Incorporated Biphasic Calcium Phosphate Microspheres	40:100	Electrically Polarized Withaferin A and Alginate-Incorporated Biphasic Calcium Phosphate Microspheres Exhibit Osteogenicity and Antibacterial Activity In Vitro.					
36615281	6	58	theme	osteogenic	1070:1079	arg1	differentiation					1081:1095	The osteogenic differentiation	1066:1095	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres	1066:1138	The osteogenic differentiation of MG 63 cells on BCP-WFA-ALG microspheres exhibited an increased expression of osteogenic marker genes in the case of the BCP-WFA-ALG composite microspheres.					
36615281	2	59	theme	alginate-incorporated	401:421	arg1	BCP-WFA-ALG					451:461	BCP-WFA-ALG	451:461	BCP-WFA-ALG	451:461	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	2	59	theme	alginate-incorporated	401:421	arg1	phosphate					440:448	alginate-incorporated biphasic calcium phosphate	401:448	alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG)	401:462	These withaferin A and alginate-incorporated biphasic calcium phosphate (BCP-WFA-ALG) microspheres were then negatively polarized, and the formation of biphasic calcium phosphates was validated by X-ray diffraction study.					
36615281	1	60	theme	withaferin	273:282	arg1	A					284:284	withaferin A	273:284	withaferin A	273:284	Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion method and, subsequently, withaferin A was incorporated in the microspheres to evaluate their efficacy in biomedical applications.					
34982091	4	0	theme	zirconyl	841:848	arg1	chloride					850:857	zirconyl chloride	841:857	zirconyl chloride	841:857	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	3	1	theme	printed	631:637	arg1	scaffolds					639:647	the printed scaffolds	627:647	the printed scaffolds	627:647	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	2	2	theme	3D	318:319	arg1	printing					321:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	2	theme	3D	318:319	arg1	method					345:350	a promising method	333:350	a promising method to fabricate 3D scaffolds with various architectures	333:403	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	1	3	theme	stable	221:226	arg1	hydrogels					238:246	stable and tough hydrogels	221:246	stable and tough hydrogels with intricate shapes	221:268	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	9	4	theme	load-bearing	1598:1609	arg1	capacity					1611:1618	the load-bearing capacity	1594:1618	the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel	1594:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	1	5	theme	tough	232:236	arg1	hydrogels					238:246	stable and tough hydrogels	221:246	stable and tough hydrogels with intricate shapes	221:268	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	10	6	theme	hydrogel	1870:1877	arg1	composites					1879:1888	tough-soft hydrogel composites	1859:1888	tough-soft hydrogel composites	1859:1888	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	1	7	theme	high	153:156	arg1	toughness					158:166	high toughness	153:166	high toughness	153:166	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	9	8	theme	tough	1627:1631	arg1	scaffold					1633:1640	the tough scaffold	1623:1640	the tough scaffold	1623:1640	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	3	9	theme	second	699:704	arg1	network					706:712	the second network	695:712	the second network	695:712	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	4	10	theme	Zr4+	902:905	arg1	ions					907:910	the Zr4+ ions	898:910	the Zr4+ ions	898:910	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	0	11	theme	tissue-like	88:98	arg1	composite					109:117	a tissue-like hydrogel composite	86:117	a tissue-like hydrogel composite	86:117	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	5	12	theme	tensile	1039:1045	arg1	stress					1056:1061	a tensile breaking stress	1037:1061	a tensile breaking stress of 1-2 MPa	1037:1072	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	9	13	theme	microenvironment	1656:1671	arg1	capacity					1611:1618	the load-bearing capacity	1594:1618	the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel	1594:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	4	14	theme	coordination	867:878	arg1	complexes					880:888	coordination complexes	867:888	coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan	867:946	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	7	15	theme	printing	1286:1293	arg1	parameters					1295:1304	the printing parameters	1282:1304	the printing parameters	1282:1304	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	3	16	theme	fast	533:536	arg1	transition					549:558	the fast sol-to-gel transition	529:558	the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide	529:605	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	9	17	from	Chondrocytes	1491:1502	arg1	composite					1520:1528	the hydrogel composite	1507:1528	the hydrogel composite	1507:1528	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	9	18	theme	embedded	1699:1706	arg1	gel					1720:1722	the embedded soft fibrin gel	1695:1722	the embedded soft fibrin gel	1695:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	8	19	theme	printed	1402:1408	arg1	scaffold					1425:1432	the printed tough hydrogel scaffold	1398:1432	the printed tough hydrogel scaffold	1398:1432	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	1	20	theme	structural	282:291	arg1	support					293:299	a structural support	280:299	a structural support	280:299	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	3	21	theme	κ-carrageenan	563:575	arg1	transition					549:558	the fast sol-to-gel transition	529:558	the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide	529:605	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	2	22	with	structures	439:448	arg1	fidelity					460:467	high fidelity	455:467	high fidelity	455:467	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	22	with	structures	439:448	arg1	resolution					473:482	resolution	473:482	resolution	473:482	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	23	theme	high	455:458	arg1	fidelity					460:467	high fidelity	455:467	high fidelity	455:467	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	8	24	theme	hydrogel	1416:1423	arg1	scaffold					1425:1432	the printed tough hydrogel scaffold	1398:1432	the printed tough hydrogel scaffold	1398:1432	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	6	25	dep	times	1167:1171	arg1	150					1163:1165	150	1163:1165	150	1163:1165	The printed grid can hold 150 times its own weight.					
34982091	10	26	theme	biomedical	1993:2002	arg1	devices					2004:2010	biomedical devices	1993:2010	biomedical devices	1993:2010	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	1	27	with	tissues	140:146	arg1	toughness					158:166	high toughness	153:166	high toughness	153:166	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	4	28	theme	κ-carrageenan	934:946	arg1	κ-carrageenan					934:946	κ-carrageenan	934:946	κ-carrageenan	934:946	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	4	28	theme	κ-carrageenan	934:946	arg1	ions					907:910	the Zr4+ ions	898:910	the Zr4+ ions	898:910	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	4	28	theme	κ-carrageenan	934:946	arg1	groups					924:929	sulfate groups	916:929	sulfate groups of κ-carrageenan	916:946	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	8	29	theme	cell-laden	1441:1450	arg1	hydrogel					1459:1466	a cell-laden fibrin hydrogel	1439:1466	a cell-laden fibrin hydrogel as the soft substance	1439:1488	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	0	30	theme	3D	0:1	arg1	printing					3:10	3D printing	0:10	3D printing of a tough double-network hydrogel	0:45	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	2	31	theme	various	383:389	arg1	architectures					391:403	various architectures	383:403	various architectures	383:403	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	1	32	theme	intricate	253:261	arg1	shapes					263:268	intricate shapes	253:268	intricate shapes	253:268	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	9	33	theme	hydrogel	1511:1518	arg1	composite					1520:1528	the hydrogel composite	1507:1528	the hydrogel composite	1507:1528	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	10	34	theme	good	1813:1816	arg1	stability					1818:1826	good stability	1813:1826	good stability	1813:1826	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	3	35	from	transition	549:558	arg1	solution					584:591	the solution	580:591	the solution of acrylamide	580:605	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	0	36	theme	tough	17:21	arg1	hydrogel					38:45	a tough double-network hydrogel	15:45	a tough double-network hydrogel	15:45	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	7	37	theme	high	1218:1221	arg1	ratio					1230:1234	a high aspect ratio	1216:1234	a high aspect ratio	1216:1234	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	2	38	theme	tough	424:428	arg1	challenge					495:503	a challenge	493:503	a challenge	493:503	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	38	theme	tough	424:428	arg1	structures					439:448	printing tough hydrogel structures	415:448	printing tough hydrogel structures with high fidelity and resolution	415:482	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	39	theme	Extrusion-based	302:316	arg1	printing					321:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	39	theme	Extrusion-based	302:316	arg1	method					345:350	a promising method	333:350	a promising method to fabricate 3D scaffolds with various architectures	333:403	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	0	40	theme	hydrogel	38:45	arg1	printing					3:10	3D printing	0:10	3D printing of a tough double-network hydrogel	0:45	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	0	40	theme	hydrogel	38:45	arg1	use					55:57	its use	51:57	its use as a scaffold	51:71	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	5	41	theme	Young	1108:1112	arg1	modulus					1116:1122	Young's modulus	1108:1122	Young's modulus of 4-10 MPa	1108:1134	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	42	theme	mechanical	1009:1018	arg1	properties					1020:1029	good mechanical properties	1004:1029	good mechanical properties	1004:1029	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	10	43	theme	hydrogel	1769:1776	arg1	constructs					1778:1787	hydrogel constructs	1769:1787	hydrogel constructs with high toughness and good stability	1769:1826	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	4	44	theme	κ-carrageenan/polyacrylamide	741:768	arg1	gels					785:788	κ-carrageenan/polyacrylamide double-network gels	741:788	κ-carrageenan/polyacrylamide double-network gels	741:788	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	9	45	theme	cyclic	1560:1565	arg1	compression					1567:1577	cyclic compression	1560:1577	cyclic compression	1560:1577	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	5	46	theme	breaking	1047:1054	arg1	stress					1056:1061	a tensile breaking stress	1037:1061	a tensile breaking stress of 1-2 MPa	1037:1072	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	7	47	theme	printed	1192:1198	arg1	constructs					1200:1209	3D printed constructs	1189:1209	3D printed constructs with a high aspect ratio and shape fidelity	1189:1253	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	5	48	contain	possess	996:1002	arg2	properties					1020:1029	good mechanical properties	1004:1029	good mechanical properties	1004:1029	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	48	contain	possess	996:1002	arg1	stable					976:981	stable	976:981	stable	976:981	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	48	contain	possess	996:1002	arg1	hydrogels					962:970	The obtained hydrogels	949:970	The obtained hydrogels	949:970	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	4	49	theme	gels	785:788	arg1	constructs					727:736	The printed constructs	715:736	The printed constructs of κ-carrageenan/polyacrylamide double-network gels	715:788	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	7	50	dep	ratio	1230:1234	arg1	fidelity					1246:1253	fidelity	1246:1253	fidelity	1246:1253	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	9	51	theme	fibrin	1713:1718	arg1	gel					1720:1722	the embedded soft fibrin gel	1695:1722	the embedded soft fibrin gel	1695:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	10	52	theme	tough-soft	1859:1868	arg1	composites					1879:1888	tough-soft hydrogel composites	1859:1888	tough-soft hydrogel composites	1859:1888	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	7	53	with	constructs	1200:1209	arg1	shape					1240:1244	shape	1240:1244	shape	1240:1244	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	7	53	with	constructs	1200:1209	arg1	ratio					1230:1234	a high aspect ratio	1216:1234	a high aspect ratio	1216:1234	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	9	54	theme	high	1539:1542	arg1	viability					1544:1552	high viability	1539:1552	high viability	1539:1552	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	4	55	theme	chloride	850:857	arg1	solution					829:836	an aqueous solution	818:836	an aqueous solution of zirconyl chloride	818:857	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	5	56	from	water	986:990	arg1	stable					976:981	stable	976:981	stable	976:981	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	56	from	water	986:990	arg1	hydrogels					962:970	The obtained hydrogels	949:970	The obtained hydrogels	949:970	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	3	57	theme	precursor	668:676	arg1	solution					678:685	the precursor solution	664:685	the precursor solution to form the second network	664:712	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	6	58	theme	own	1177:1179	arg1	weight					1181:1186	its own weight	1173:1186	its own weight	1173:1186	The printed grid can hold 150 times its own weight.					
34982091	5	59	from	stable	976:981	arg1	water					986:990	water	986:990	water	986:990	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	4	60	theme	aqueous	821:827	arg1	solution					829:836	an aqueous solution	818:836	an aqueous solution of zirconyl chloride	818:857	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	1	61	with	hydrogels	238:246	arg1	shapes					263:268	intricate shapes	253:268	intricate shapes	253:268	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	0	62	theme	hydrogel	100:107	arg1	composite					109:117	a tissue-like hydrogel composite	86:117	a tissue-like hydrogel composite	86:117	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	9	63	theme	favorable	1646:1654	arg1	microenvironment					1656:1671	favorable microenvironment	1646:1671	favorable microenvironment	1646:1671	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	8	64	theme	hydrogel	1368:1375	arg1	composite					1377:1385	a hydrogel composite	1366:1385	a hydrogel composite	1366:1385	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	9	65	theme	scaffold	1633:1640	arg1	capacity					1611:1618	the load-bearing capacity	1594:1618	the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel	1594:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	3	66	theme	sol-to-gel	538:547	arg1	transition					549:558	the fast sol-to-gel transition	529:558	the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide	529:605	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	10	67	with	constructs	1778:1787	arg1	toughness					1799:1807	high toughness	1794:1807	high toughness	1794:1807	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	10	67	with	constructs	1778:1787	arg1	stability					1818:1826	good stability	1813:1826	good stability	1813:1826	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	10	68	theme	printing	1747:1754	arg1	strategy					1756:1763	this printing strategy	1742:1763	this printing strategy for hydrogel constructs with high toughness and good stability	1742:1826	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	10	69	theme	other	1910:1914	arg1	systems					1916:1922	other systems	1910:1922	other systems	1910:1922	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	10	70	theme	high	1794:1797	arg1	toughness					1799:1807	high toughness	1794:1807	high toughness	1794:1807	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	8	71	theme	tough	1410:1414	arg1	scaffold					1425:1432	the printed tough hydrogel scaffold	1398:1432	the printed tough hydrogel scaffold	1398:1432	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	6	72	theme	printed	1141:1147	arg1	grid					1149:1152	The printed grid	1137:1152	The printed grid	1137:1152	The printed grid can hold 150 times its own weight.					
34982091	9	73	theme	soft	1708:1711	arg1	gel					1720:1722	the embedded soft fibrin gel	1695:1722	the embedded soft fibrin gel	1695:1722	Chondrocytes in the hydrogel composite maintain high viability after cyclic compression, demonstrating the load-bearing capacity of the tough scaffold and favorable microenvironment for cells provided by the embedded soft fibrin gel.					
34982091	10	74	theme	structural	1935:1944	arg1	elements					1946:1953	structural elements	1935:1953	structural elements	1935:1953	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	1	75	theme	biological	129:138	arg1	cartilage					176:184	cartilage	176:184	cartilage	176:184	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	1	75	theme	biological	129:138	arg1	tissues					140:146	biological tissues	129:146	biological tissues with high toughness such as cartilage	129:184	To mimic biological tissues with high toughness such as cartilage, it is highly desired to fabricate stable and tough hydrogels with intricate shapes to act as a structural support.					
34982091	5	76	theme	%	1101:1101	arg1	strain					1084:1089	breaking strain	1075:1089	breaking strain of 100-150%	1075:1101	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	4	77	theme	sulfate	916:922	arg1	κ-carrageenan					934:946	κ-carrageenan	934:946	κ-carrageenan	934:946	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	4	77	theme	sulfate	916:922	arg1	groups					924:929	sulfate groups	916:929	sulfate groups of κ-carrageenan	916:946	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	8	78	theme	fibrin	1452:1457	arg1	hydrogel					1459:1466	a cell-laden fibrin hydrogel	1439:1466	a cell-laden fibrin hydrogel as the soft substance	1439:1488	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	5	79	theme	MPa	1070:1072	arg1	stress					1056:1061	a tensile breaking stress	1037:1061	a tensile breaking stress of 1-2 MPa	1037:1072	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	80	theme	obtained	953:960	arg1	stable					976:981	stable	976:981	stable	976:981	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	5	80	theme	obtained	953:960	arg1	hydrogels					962:970	The obtained hydrogels	949:970	The obtained hydrogels	949:970	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	4	81	theme	printed	719:725	arg1	constructs					727:736	The printed constructs	715:736	The printed constructs of κ-carrageenan/polyacrylamide double-network gels	715:788	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
34982091	5	82	theme	breaking	1075:1082	arg1	strain					1084:1089	breaking strain	1075:1089	breaking strain of 100-150%	1075:1101	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	8	83	theme	soft	1475:1478	arg1	substance					1480:1488	the soft substance	1471:1488	the soft substance	1471:1488	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	2	84	theme	promising	335:343	arg1	printing					321:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing	302:328	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	84	theme	promising	335:343	arg1	method					345:350	a promising method	333:350	a promising method to fabricate 3D scaffolds with various architectures	333:403	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	7	85	theme	aspect	1223:1228	arg1	ratio					1230:1234	a high aspect ratio	1216:1234	a high aspect ratio	1216:1234	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	3	86	theme	acrylamide	596:605	arg1	solution					584:591	the solution	580:591	the solution of acrylamide	580:605	In this work, we adopt the fast sol-to-gel transition of κ-carrageenan in the solution of acrylamide upon cooling to fix the printed scaffolds and polymerize the precursor solution to form the second network.					
34982091	0	87	theme	double-network	23:36	arg1	hydrogel					38:45	a tough double-network hydrogel	15:45	a tough double-network hydrogel	15:45	3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite.					
34982091	5	88	theme	MPa	1132:1134	arg1	modulus					1116:1122	Young's modulus	1108:1122	Young's modulus of 4-10 MPa	1108:1134	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	2	89	theme	hydrogel	430:437	arg1	challenge					495:503	a challenge	493:503	a challenge	493:503	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	89	theme	hydrogel	430:437	arg1	structures					439:448	printing tough hydrogel structures	415:448	printing tough hydrogel structures with high fidelity and resolution	415:482	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	90	theme	3D	365:366	arg1	scaffolds					368:376	3D scaffolds	365:376	3D scaffolds	365:376	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	10	91	from	applications	1977:1988	arg1	devices					2004:2010	biomedical devices	1993:2010	biomedical devices	1993:2010	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	5	92	theme	good	1004:1007	arg1	properties					1020:1029	good mechanical properties	1004:1029	good mechanical properties	1004:1029	The obtained hydrogels are stable in water and possess good mechanical properties, with a tensile breaking stress of 1-2 MPa, breaking strain of 100-150%, and Young's modulus of 4-10 MPa.					
34982091	2	93	theme	printing	415:422	arg1	challenge					495:503	a challenge	493:503	a challenge	493:503	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	2	93	theme	printing	415:422	arg1	structures					439:448	printing tough hydrogel structures	415:448	printing tough hydrogel structures with high fidelity and resolution	415:482	Extrusion-based 3D printing is a promising method to fabricate 3D scaffolds with various architectures; however, printing tough hydrogel structures with high fidelity and resolution is still a challenge.					
34982091	8	94	theme	biomimetic	1322:1331	arg1	strategy					1333:1340	a biomimetic strategy	1320:1340	a biomimetic strategy	1320:1340	Furthermore, a biomimetic strategy is applied to construct a hydrogel composite by filling the printed tough hydrogel scaffold with a cell-laden fibrin hydrogel as the soft substance.					
34982091	7	95	theme	3D	1189:1190	arg1	constructs					1200:1209	3D printed constructs	1189:1209	3D printed constructs with a high aspect ratio and shape fidelity	1189:1253	3D printed constructs with a high aspect ratio and shape fidelity are obtained by optimizing the printing parameters.					
34982091	10	96	theme	tissue	2016:2021	arg1	engineering					2023:2033	tissue engineering	2016:2033	tissue engineering	2016:2033	We envision that this printing strategy for hydrogel constructs with high toughness and good stability, as well as the method to form tough-soft hydrogel composites, can be extended to other systems to develop structural elements and scaffolds towards applications in biomedical devices and tissue engineering.					
34982091	4	97	theme	double-network	770:783	arg1	gels					785:788	κ-carrageenan/polyacrylamide double-network gels	741:788	κ-carrageenan/polyacrylamide double-network gels	741:788	The printed constructs of κ-carrageenan/polyacrylamide double-network gels are toughened by soaking in an aqueous solution of zirconyl chloride to form coordination complexes between the Zr4+ ions and sulfate groups of κ-carrageenan.					
37128714	1	0	theme	alkali	284:289	arg1	enzymes					254:260	enzymes	254:260	enzymes	254:260	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	1	0	theme	alkali	284:289	arg1	alkali					284:289	alkali	284:289	alkali	284:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	1	0	theme	alkali	284:289	arg1	amount					274:279	a small amount	266:279	a small amount of alkali	266:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	2	1	theme	application	536:546	arg1	performance					548:558	the preparation method, performance, and application performance	495:558	the preparation method, performance, and application performance of the two nanocelluloses	495:584	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	10	2	theme	medical	1699:1705	arg1	material					1707:1714	a medical material	1697:1714	a medical material	1697:1714	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	10	2	theme	medical	1699:1705	arg1	growth					1659:1664	the cell growth	1650:1664	the cell growth	1650:1664	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	8	3	theme	break	1288:1292	arg1	elongation					1294:1303	the break elongation	1284:1303	the break elongation	1284:1303	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	1	4	theme	unmodified	209:218	arg1	method					242:247	an efficient, unmodified, and clean biological method	195:247	an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali	195:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	9	5	theme	composite	1475:1483	arg1	membrane					1485:1492	the composite membrane	1471:1492	the composite membrane hydrophilic	1471:1504	In brief, CNFs can make the composite membrane hydrophobic and with superior extension, and CNCs can make the composite membrane hydrophilic and enhance its strength.					
37128714	5	6	theme	Pa	903:904	arg1	s					906:906	7.46 Pa s	898:906	7.46 Pa s	898:906	The solution viscosity of CNFs and CNCs reached 7.46 Pa s and 1.91 Pa s, respectively.					
37128714	8	7	theme	PLA-CNFs	1226:1233	arg1	strength					1214:1221	The breaking strength	1201:1221	The breaking strength of PLA-CNFs and PLA-CNCs	1201:1246	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	0	8	from	Preparation	0:10	arg1	film					152:155	the electrospun composite film	126:155	the electrospun composite film	126:155	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	9	9	theme	hydrophilic	1494:1504	arg1	membrane					1485:1492	the composite membrane	1471:1492	the composite membrane hydrophilic	1471:1504	In brief, CNFs can make the composite membrane hydrophobic and with superior extension, and CNCs can make the composite membrane hydrophilic and enhance its strength.					
37128714	3	10	theme	crystallinity	653:665	arg1	index					667:671	a crystallinity index	651:671	a crystallinity index of 58.2 and 83.5%	651:689	The result of this study indicated that CNFs and CNCs exhibited a crystallinity index of 58.2 and 83.5%, respectively.					
37128714	2	11	theme	performance	519:529	arg1	performance					548:558	the preparation method, performance, and application performance	495:558	the preparation method, performance, and application performance of the two nanocelluloses	495:584	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	10	12	theme	composite	1541:1549	arg1	films					1551:1555	Both the composite films	1532:1555	Both the composite films	1532:1555	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	2	13	theme	following	442:450	arg1	comparison					452:461	the following comparison	438:461	the following comparison	438:461	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	10	14	theme	cell	1654:1657	arg1	material					1707:1714	a medical material	1697:1714	a medical material	1697:1714	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	10	14	theme	cell	1654:1657	arg1	growth					1659:1664	the cell growth	1650:1664	the cell growth	1650:1664	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	2	15	theme	nanocelluloses	571:584	arg1	performance					548:558	the preparation method, performance, and application performance	495:558	the preparation method, performance, and application performance of the two nanocelluloses	495:584	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	6	16	theme	potential	966:974	arg1	values					976:981	zeta potential values	961:981	zeta potential values of -88.26 mV and -26.40 mV	961:1008	CNFs and CNCs exhibited zeta potential values of -88.26 mV and -26.40 mV, respectively.					
37128714	0	17	theme	chemical	87:94	arg1	method					96:101	the chemical method	83:101	the chemical method	83:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	2	18	theme	future	409:414	arg1	applications					416:427	future applications	409:427	future applications	409:427	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	6	19	theme	zeta	961:964	arg1	values					976:981	zeta potential values	961:981	zeta potential values of -88.26 mV and -26.40 mV	961:1008	CNFs and CNCs exhibited zeta potential values of -88.26 mV and -26.40 mV, respectively.					
37128714	3	20	theme	%	689:689	arg1	index					667:671	a crystallinity index	651:671	a crystallinity index of 58.2 and 83.5%	651:689	The result of this study indicated that CNFs and CNCs exhibited a crystallinity index of 58.2 and 83.5%, respectively.					
37128714	2	21	theme	accurate	377:384	arg1	selection					395:403	an accurate targeted selection	374:403	an accurate targeted selection for future applications	374:427	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	5	22	theme	Pa	917:918	arg1	s					920:920	1.91 Pa s	912:920	1.91 Pa s	912:920	The solution viscosity of CNFs and CNCs reached 7.46 Pa s and 1.91 Pa s, respectively.					
37128714	9	23	theme	composite	1393:1401	arg1	membrane					1403:1410	the composite membrane	1389:1410	the composite membrane	1389:1410	In brief, CNFs can make the composite membrane hydrophobic and with superior extension, and CNCs can make the composite membrane hydrophilic and enhance its strength.					
37128714	1	24	theme	biological	231:240	arg1	method					242:247	an efficient, unmodified, and clean biological method	195:247	an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali	195:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	4	25	theme	nm	742:743	arg1	diameter					751:758	a diameter	749:758	a diameter (D) of 1.9 nm	749:772	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	25	theme	nm	742:743	arg1	L					730:730	L	730:730	L	730:730	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	25	theme	nm	742:743	arg1	length					722:727	a mean length	715:727	a mean length (L) of 192.3 nm	715:743	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	25	theme	nm	742:743	arg1	D					761:761	D	761:761	D	761:761	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	10	26	theme	PLA-CNFs	1602:1609	arg1	film					1611:1614	the PLA-CNFs film	1598:1614	the PLA-CNFs film	1598:1614	Both the composite films conformed to the non-toxic standard, and the PLA-CNFs film more significantly contributed to the cell growth, which is expected to serve as a medical material.					
37128714	7	27	theme	138.7	1114:1118	arg1	angles					1104:1109	water contact angles	1090:1109	water contact angles of 138.7 and 34.5°	1090:1128	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	6	28	theme	mV	993:994	arg1	values					976:981	zeta potential values	961:981	zeta potential values of -88.26 mV and -26.40 mV	961:1008	CNFs and CNCs exhibited zeta potential values of -88.26 mV and -26.40 mV, respectively.					
37128714	1	29	with	method	242:247	arg1	enzymes					254:260	enzymes	254:260	enzymes	254:260	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	1	29	with	method	242:247	arg1	alkali					284:289	alkali	284:289	alkali	284:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	1	29	with	method	242:247	arg1	amount					274:279	a small amount	266:279	a small amount of alkali	266:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	7	30	theme	contact	1096:1102	arg1	angles					1104:1109	water contact angles	1090:1109	water contact angles of 138.7 and 34.5°	1090:1128	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	0	31	theme	nanocellulose	15:27	arg1	application					111:121	its application	107:121	its application on the electrospun composite film	107:155	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	0	31	theme	nanocellulose	15:27	arg1	Preparation					0:10	Preparation	0:10	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method	0:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	8	32	theme	PLA-CNCs	1326:1333	arg1	PLA-CNFs					1346:1353	PLA-CNCs (32.16%) < PLA-CNFs	1326:1353	PLA-CNCs (32.16%) < PLA-CNFs (34.70%)	1326:1362	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	8	32	theme	PLA-CNCs	1326:1333	arg1	%					1361:1361	34.70%	1356:1361	34.70%	1356:1361	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	5	33	theme	CNCs	885:888	arg1	viscosity					863:871	The solution viscosity	850:871	The solution viscosity of CNFs and CNCs	850:888	The solution viscosity of CNFs and CNCs reached 7.46 Pa s and 1.91 Pa s, respectively.					
37128714	7	34	theme	electrospun	1029:1039	arg1	film					1051:1054	The electrospun composite film	1025:1054	The electrospun composite film of PLA-CNFs and PLA-CNCs	1025:1079	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	0	35	theme	biological	34:43	arg1	method					45:50	a biological method	32:50	a biological method from hemp stalk in contrast to the chemical method	32:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	4	36	theme	average	783:789	arg1	L					791:791	the average L	779:791	the average L	779:791	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	1	37	theme	chemical	322:329	arg1	method					331:336	the chemical method	318:336	the chemical method involving a strong acid	318:360	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	9	38	theme	superior	1433:1440	arg1	extension					1442:1450	superior extension	1433:1450	superior extension	1433:1450	In brief, CNFs can make the composite membrane hydrophobic and with superior extension, and CNCs can make the composite membrane hydrophilic and enhance its strength.					
37128714	0	39	from	stalk	62:66	arg1	contrast					71:78	contrast	71:78	contrast to the chemical method	71:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	0	39	from	stalk	62:66	arg1	method					45:50	a biological method	32:50	a biological method from hemp stalk in contrast to the chemical method	32:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	7	40	theme	water	1090:1094	arg1	angles					1104:1109	water contact angles	1090:1109	water contact angles of 138.7 and 34.5°	1090:1128	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	0	41	theme	electrospun	130:140	arg1	film					152:155	the electrospun composite film	126:155	the electrospun composite film	126:155	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	4	42	theme	CNCs	802:805	arg1	D					797:797	D	797:797	D	797:797	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	42	theme	CNCs	802:805	arg1	L					791:791	the average L	779:791	the average L	779:791	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	7	43	theme	contact	1149:1155	arg1	angle					1157:1161	the water-oil contact angle	1135:1161	the water-oil contact angle	1135:1161	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	4	44	theme	nm	771:772	arg1	diameter					751:758	a diameter	749:758	a diameter (D) of 1.9 nm	749:772	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	44	theme	nm	771:772	arg1	L					730:730	L	730:730	L	730:730	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	44	theme	nm	771:772	arg1	length					722:727	a mean length	715:727	a mean length (L) of 192.3 nm	715:743	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	44	theme	nm	771:772	arg1	D					761:761	D	761:761	D	761:761	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	8	45	theme	<	1344:1344	arg1	PLA-CNFs					1346:1353	PLA-CNCs (32.16%) < PLA-CNFs	1326:1353	PLA-CNCs (32.16%) < PLA-CNFs (34.70%)	1326:1362	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	8	45	theme	<	1344:1344	arg1	%					1361:1361	34.70%	1356:1361	34.70%	1356:1361	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	2	46	theme	targeted	386:393	arg1	selection					395:403	an accurate targeted selection	374:403	an accurate targeted selection for future applications	374:427	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	1	47	theme	small	268:272	arg1	alkali					284:289	alkali	284:289	alkali	284:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	1	47	theme	small	268:272	arg1	amount					274:279	a small amount	266:279	a small amount of alkali	266:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	2	48	theme	method	511:516	arg1	performance					548:558	the preparation method, performance, and application performance	495:558	the preparation method, performance, and application performance of the two nanocelluloses	495:584	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	3	49	theme	study	606:610	arg1	result					591:596	The result	587:596	The result of this study	587:610	The result of this study indicated that CNFs and CNCs exhibited a crystallinity index of 58.2 and 83.5%, respectively.					
37128714	5	50	theme	solution	854:861	arg1	viscosity					863:871	The solution viscosity	850:871	The solution viscosity of CNFs and CNCs	850:888	The solution viscosity of CNFs and CNCs reached 7.46 Pa s and 1.91 Pa s, respectively.					
37128714	7	51	theme	PLA-CNCs	1072:1079	arg1	film					1051:1054	The electrospun composite film	1025:1054	The electrospun composite film of PLA-CNFs and PLA-CNCs	1025:1079	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	1	52	with	CNCs	308:311	arg1	method					331:336	the chemical method	318:336	the chemical method involving a strong acid	318:360	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	8	53	theme	breaking	1205:1212	arg1	strength					1214:1221	The breaking strength	1201:1221	The breaking strength of PLA-CNFs and PLA-CNCs	1201:1246	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	2	54	theme	preparation	499:509	arg1	method					511:516	preparation method	499:516	preparation method	499:516	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37128714	1	55	theme	strong	350:355	arg1	acid					357:360	a strong acid	348:360	a strong acid	348:360	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	8	56	theme	PLA-CNFs	1346:1353	arg1	order					1317:1321	an order	1314:1321	an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%)	1314:1362	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	0	57	theme	composite	142:150	arg1	film					152:155	the electrospun composite film	126:155	the electrospun composite film	126:155	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	5	58	theme	CNFs	876:879	arg1	viscosity					863:871	The solution viscosity	850:871	The solution viscosity of CNFs and CNCs	850:888	The solution viscosity of CNFs and CNCs reached 7.46 Pa s and 1.91 Pa s, respectively.					
37128714	7	59	theme	water-oil	1139:1147	arg1	angle					1157:1161	the water-oil contact angle	1135:1161	the water-oil contact angle	1135:1161	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	7	60	theme	PLA-CNFs	1059:1066	arg1	film					1051:1054	The electrospun composite film	1025:1054	The electrospun composite film of PLA-CNFs and PLA-CNCs	1025:1079	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	0	61	from	application	111:121	arg1	film					152:155	the electrospun composite film	126:155	the electrospun composite film	126:155	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	8	62	theme	PLA-CNCs	1239:1246	arg1	strength					1214:1221	The breaking strength	1201:1221	The breaking strength of PLA-CNFs and PLA-CNCs	1201:1246	The breaking strength of PLA-CNFs and PLA-CNCs reached 96.07 cN and 163.23 cN, and the break elongation followed an order of PLA-CNCs (32.16%) < PLA-CNFs (34.70%).					
37128714	4	63	theme	mean	717:720	arg1	L					730:730	L	730:730	L	730:730	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	63	theme	mean	717:720	arg1	length					722:727	a mean length	715:727	a mean length (L) of 192.3 nm	715:743	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	7	64	theme	composite	1041:1049	arg1	film					1051:1054	The electrospun composite film	1025:1054	The electrospun composite film of PLA-CNFs and PLA-CNCs	1025:1079	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	7	65	theme	34.5°	1124:1128	arg1	angles					1104:1109	water contact angles	1090:1109	water contact angles of 138.7 and 34.5°	1090:1128	The electrospun composite film of PLA-CNFs and PLA-CNCs achieved water contact angles of 138.7 and 34.5°, and the water-oil contact angle reached 24.7 and 30.5°, respectively.					
37128714	1	66	theme	efficient	198:206	arg1	method					242:247	an efficient, unmodified, and clean biological method	195:247	an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali	195:289	In this study, CNFs were provided by an efficient, unmodified, and clean biological method with enzymes and a small amount of alkali, compared to the CNCs with the chemical method involving a strong acid.					
37128714	0	67	theme	hemp	57:60	arg1	stalk					62:66	hemp stalk	57:66	hemp stalk in contrast to the chemical method	57:101	Preparation of nanocellulose by a biological method from hemp stalk in contrast to the chemical method and its application on the electrospun composite film.					
37128714	4	68	contain	had	711:713	arg2	D					761:761	D	761:761	D	761:761	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	68	contain	had	711:713	arg1	CNFs					706:709	CNFs	706:709	CNFs	706:709	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	68	contain	had	711:713	arg2	diameter					751:758	a diameter	749:758	a diameter (D) of 1.9 nm	749:772	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	68	contain	had	711:713	arg2	L					730:730	L	730:730	L	730:730	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	4	68	contain	had	711:713	arg2	length					722:727	a mean length	715:727	a mean length (L) of 192.3 nm	715:743	CNFs had a mean length (L) of 192.3 nm and a diameter (D) of 1.9 nm, and the average L and D of CNCs reached 123.6 nm and 3.7 nm, respectively.					
37128714	6	69	theme	mV	1007:1008	arg1	values					976:981	zeta potential values	961:981	zeta potential values of -88.26 mV and -26.40 mV	961:1008	CNFs and CNCs exhibited zeta potential values of -88.26 mV and -26.40 mV, respectively.					
37128714	2	70	from	differences	480:490	arg1	performance					548:558	the preparation method, performance, and application performance	495:558	the preparation method, performance, and application performance of the two nanocelluloses	495:584	To provide an accurate targeted selection for future applications, we made the following comparison by analyzing the differences in the preparation method, performance, and application performance of the two nanocelluloses.					
37028616	0	0	theme	thermal	99:105	arg1	storage					114:120	thermal energy storage	99:120	thermal energy storage	99:120	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	7	1	theme	management	1421:1430	arg1	field					1405:1409	the field	1401:1409	the field of energy management and thermal equipment temperature regulation	1401:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	7	2	theme	temperature	1454:1464	arg1	regulation					1466:1475	temperature regulation	1454:1475	temperature regulation	1454:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	5	3	theme	high	861:864	arg1	properties					914:923	non-leakage properties	902:923	non-leakage properties under prolonged high temperature conditions	902:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	5	3	theme	high	861:864	arg1	efficiency					880:889	high encapsulation efficiency	861:889	high encapsulation efficiency of 98.8 %	861:899	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	4	4	theme	PW	560:561	arg1	emulsions					563:571	The PW emulsions	556:571	The PW emulsions	556:571	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	7	5	theme	energy	1414:1419	arg1	management					1421:1430	energy management	1414:1430	energy management	1414:1430	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	6	6	theme	satisfactory	1072:1083	arg1	performance					1085:1095	satisfactory performance	1072:1095	satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials	1072:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	1	7	theme	low	171:173	arg1	conductivity					183:194	low thermal conductivity	171:194	low thermal conductivity of PCMs	171:202	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	3	8	theme	thermal	517:523	arg1	conductivity					525:536	high thermal conductivity	512:536	high thermal conductivity	512:536	The PW microcapsules were then loaded into the metal foam to endow high thermal conductivity to the composite.					
37028616	6	9	theme	conductivity	1117:1128	arg1	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	9	theme	conductivity	1117:1128	arg1	capacity					1147:1154	thermal storage capacity	1131:1154	thermal storage capacity	1131:1154	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	9	theme	conductivity	1117:1128	arg1	reliability					1168:1178	thermal reliability	1160:1178	thermal reliability	1160:1178	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	0	10	theme	energy	107:112	arg1	storage					114:120	thermal energy storage	99:120	thermal energy storage	99:120	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	5	11	theme	high	941:944	arg1	conditions					958:967	prolonged high temperature conditions	931:967	prolonged high temperature conditions	931:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	6	12	theme	materials	1255:1263	arg1	regulation					1225:1234	effective temperature regulation	1203:1234	effective temperature regulation of heat generating materials	1203:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	4	13	theme	satisfactory	709:720	arg1	capacity					742:749	a satisfactory latent heat-storage capacity	707:749	a satisfactory latent heat-storage capacity	707:749	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	4	14	theme	favorable	667:675	arg1	stability					693:701	favorable thermal cycling stability	667:701	favorable thermal cycling stability	667:701	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	4	15	theme	PW	639:640	arg1	microcapsules					642:654	the PW microcapsules	635:654	the PW microcapsules	635:654	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	6	16	theme	thermal	1109:1115	arg1	conductivity					1117:1128	thermal conductivity	1109:1128	thermal conductivity	1109:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	5	17	theme	non-leakage	902:912	arg1	properties					914:923	non-leakage properties	902:923	non-leakage properties under prolonged high temperature conditions	902:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	5	17	theme	non-leakage	902:912	arg1	efficiency					880:889	high encapsulation efficiency	861:889	high encapsulation efficiency of 98.8 %	861:899	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	6	18	theme	microcapsules/copper	1040:1059	arg1	foam					1061:1064	PW microcapsules/copper foam	1037:1064	PW microcapsules/copper foam	1037:1064	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	2	19	theme	chitin	284:289	arg1	nanocrystals					291:302	chitin nanocrystals	284:302	chitin nanocrystals (ChNCs)	284:310	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	2	19	theme	chitin	284:289	arg1	ChNCs					305:309	ChNCs	305:309	ChNCs	305:309	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	1	20	theme	thermal	175:181	arg1	conductivity					183:194	low thermal conductivity	171:194	low thermal conductivity of PCMs	171:202	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	5	21	theme	encapsulation	866:878	arg1	properties					914:923	non-leakage properties	902:923	non-leakage properties under prolonged high temperature conditions	902:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	5	21	theme	encapsulation	866:878	arg1	efficiency					880:889	high encapsulation efficiency	861:889	high encapsulation efficiency of 98.8 %	861:899	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	6	22	theme	heat	1239:1242	arg1	materials					1255:1263	heat generating materials	1239:1263	heat generating materials	1239:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	3	23	theme	high	512:515	arg1	conductivity					525:536	high thermal conductivity	512:536	high thermal conductivity	512:536	The PW microcapsules were then loaded into the metal foam to endow high thermal conductivity to the composite.					
37028616	6	24	theme	foam	1061:1064	arg1	foam					1061:1064	PW microcapsules/copper foam	1037:1064	PW microcapsules/copper foam	1037:1064	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	24	theme	foam	1061:1064	arg1	composite					1024:1032	the composite	1020:1032	the composite of PW microcapsules/copper foam	1020:1064	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	25	theme	PW	1037:1038	arg1	foam					1061:1064	PW microcapsules/copper foam	1037:1064	PW microcapsules/copper foam	1037:1064	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	0	26	theme	phase	18:22	arg1	material					31:38	Microencapsulated phase change material	0:38	Microencapsulated phase change material with chitin nanocrystals	0:63	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	5	27	theme	shell	816:820	arg1	encapsulation					787:799	the encapsulation	783:799	the encapsulation of the polymer shell	783:820	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	6	28	theme	storage	1139:1145	arg1	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	28	theme	storage	1139:1145	arg1	capacity					1147:1154	thermal storage capacity	1131:1154	thermal storage capacity	1131:1154	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	0	29	theme	Microencapsulated	0:16	arg1	material					31:38	Microencapsulated phase change material	0:38	Microencapsulated phase change material with chitin nanocrystals	0:63	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	6	30	theme	generating	1244:1253	arg1	materials					1255:1263	heat generating materials	1239:1263	heat generating materials	1239:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	4	31	theme	cycling	685:691	arg1	stability					693:701	favorable thermal cycling stability	667:701	favorable thermal cycling stability	667:701	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	7	32	theme	thermal	1436:1442	arg1	equipment					1444:1452	thermal equipment	1436:1452	thermal equipment	1436:1452	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	1	33	theme	PCMs	199:202	arg1	leakage					127:133	The leakage	123:133	The leakage during the phase change process	123:165	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	1	33	theme	PCMs	199:202	arg1	conductivity					183:194	low thermal conductivity	171:194	low thermal conductivity of PCMs	171:202	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	5	34	theme	polymer	808:814	arg1	shell					816:820	the polymer shell	804:820	the polymer shell	804:820	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	7	35	theme	nanomaterials	1333:1345	arg1	strategy					1297:1304	new design strategy	1286:1304	new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation	1286:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	5	36	theme	%	899:899	arg1	properties					914:923	non-leakage properties	902:923	non-leakage properties under prolonged high temperature conditions	902:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	5	36	theme	%	899:899	arg1	efficiency					880:889	high encapsulation efficiency	861:889	high encapsulation efficiency of 98.8 %	861:899	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	6	37	theme	temperature	1213:1223	arg1	regulation					1225:1234	effective temperature regulation	1203:1234	effective temperature regulation of heat generating materials	1203:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	3	38	theme	PW	449:450	arg1	microcapsules					452:464	The PW microcapsules	445:464	The PW microcapsules	445:464	The PW microcapsules were then loaded into the metal foam to endow high thermal conductivity to the composite.					
37028616	0	39	theme	change	24:29	arg1	material					31:38	Microencapsulated phase change material	0:38	Microencapsulated phase change material with chitin nanocrystals	0:63	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	5	40	theme	temperature	946:956	arg1	conditions					958:967	prolonged high temperature conditions	931:967	prolonged high temperature conditions	931:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	3	41	theme	metal	492:496	arg1	foam					498:501	the metal foam	488:501	the metal foam	488:501	The PW microcapsules were then loaded into the metal foam to endow high thermal conductivity to the composite.					
37028616	6	42	theme	thermal	1131:1137	arg1	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	42	theme	thermal	1131:1137	arg1	capacity					1147:1154	thermal storage capacity	1131:1154	thermal storage capacity	1131:1154	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	0	43	theme	chitin	45:50	arg1	nanocrystals					52:63	chitin nanocrystals	45:63	chitin nanocrystals	45:63	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	5	44	theme	prolonged	931:939	arg1	conditions					958:967	prolonged high temperature conditions	931:967	prolonged high temperature conditions	931:967	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	1	45	theme	application	216:226	arg1	area					228:231	their application area	210:231	their application area	210:231	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	5	46	theme	high	984:987	arg1	retardancy					995:1004	high flame retardancy	984:1004	high flame retardancy	984:1004	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	7	47	theme	new	1286:1288	arg1	strategy					1297:1304	new design strategy	1286:1304	new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation	1286:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	2	48	theme	resin	405:409	arg1	shell					411:415	a dense melamine-formaldehyde resin shell	375:415	a dense melamine-formaldehyde resin shell	375:415	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	2	49	theme	dense	377:381	arg1	shell					411:415	a dense melamine-formaldehyde resin shell	375:415	a dense melamine-formaldehyde resin shell	375:415	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	5	50	theme	flame	989:993	arg1	retardancy					995:1004	high flame retardancy	984:1004	high flame retardancy	984:1004	Most importantly, the encapsulation of the polymer shell not only endows the microcapsules with high encapsulation efficiency of 98.8 %, non-leakage properties under prolonged high temperature conditions, but also with high flame retardancy.					
37028616	0	51	with	material	31:38	arg1	nanocrystals					52:63	chitin nanocrystals	45:63	chitin nanocrystals	45:63	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	2	52	theme	melamine-formaldehyde	383:403	arg1	shell					411:415	a dense melamine-formaldehyde resin shell	375:415	a dense melamine-formaldehyde resin shell	375:415	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	7	53	dep	management	1421:1430	arg1	regulation					1466:1475	temperature regulation	1454:1475	temperature regulation	1454:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	7	54	theme	equipment	1444:1452	arg1	field					1405:1409	the field	1401:1409	the field of energy management and thermal equipment temperature regulation	1401:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	2	55	theme	wax	341:343	arg1	microcapsules					350:362	paraffin wax (PW) microcapsules	332:362	paraffin wax (PW) microcapsules	332:362	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	6	56	theme	thermal	1160:1166	arg1	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	56	theme	thermal	1160:1166	arg1	reliability					1168:1178	thermal reliability	1160:1178	thermal reliability	1160:1178	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	7	57	theme	natural	1309:1315	arg1	nanomaterials					1333:1345	natural and sustainable nanomaterials	1309:1345	natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation	1309:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	7	58	theme	promising	1376:1384	arg1	application					1386:1396	promising application	1376:1396	promising application in the field of energy management and thermal equipment temperature regulation	1376:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	7	59	theme	sustainable	1321:1331	arg1	nanomaterials					1333:1345	natural and sustainable nanomaterials	1309:1345	natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation	1309:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	2	60	theme	paraffin	332:339	arg1	PW					346:347	PW	346:347	PW	346:347	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	2	60	theme	paraffin	332:339	arg1	wax					341:343	paraffin wax	332:343	paraffin wax (PW) microcapsules	332:362	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	6	61	theme	effective	1203:1211	arg1	regulation					1225:1234	effective temperature regulation	1203:1234	effective temperature regulation of heat generating materials	1203:1263	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	4	62	theme	thermal	677:683	arg1	stability					693:701	favorable thermal cycling stability	667:701	favorable thermal cycling stability	667:701	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	7	63	from	application	1386:1396	arg1	field					1405:1409	the field	1401:1409	the field of energy management and thermal equipment temperature regulation	1401:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	4	64	theme	heat-storage	729:740	arg1	capacity					742:749	a satisfactory latent heat-storage capacity	707:749	a satisfactory latent heat-storage capacity	707:749	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	4	65	theme	latent	722:727	arg1	capacity					742:749	a satisfactory latent heat-storage capacity	707:749	a satisfactory latent heat-storage capacity	707:749	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	1	66	theme	phase	146:150	arg1	process					159:165	the phase change process	142:165	the phase change process	142:165	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	4	67	dep	stability	693:701	arg1	a					665:665	a	665:665	a	665:665	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	4	68	theme	ChNCs	614:618	arg1	concentrations					596:609	low concentrations	592:609	low concentrations of ChNCs (0.3 wt%)	592:628	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	2	69	theme	Pickering	249:257	arg1	emulsion					259:266	Pickering emulsion	249:266	Pickering emulsion stabilized with chitin nanocrystals (ChNCs)	249:310	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	7	70	theme	design	1290:1295	arg1	strategy					1297:1304	new design strategy	1286:1304	new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation	1286:1475	This study provides new design strategy of natural and sustainable nanomaterials stabilized PCMs, which shows promising application in the field of energy management and thermal equipment temperature regulation.					
37028616	1	71	theme	change	152:157	arg1	process					159:165	the phase change process	142:165	the phase change process	142:165	The leakage during the phase change process and low thermal conductivity of PCMs limit their application area.					
37028616	2	72	used	used	316:319	arg2	emulsion					259:266	Pickering emulsion	249:266	Pickering emulsion stabilized with chitin nanocrystals (ChNCs)	249:310	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	4	73	theme	low	592:594	arg1	concentrations					596:609	low concentrations	592:609	low concentrations of ChNCs (0.3 wt%)	592:628	The PW emulsions could be formed at low concentrations of ChNCs (0.3 wt%), and the PW microcapsules exhibits a favorable thermal cycling stability and a satisfactory latent heat-storage capacity over 170 J/g.					
37028616	0	74	theme	Pickering	76:84	arg1	emulsion					86:93	Pickering emulsion	76:93	Pickering emulsion	76:93	Microencapsulated phase change material with chitin nanocrystals stabilized Pickering emulsion for thermal energy storage.					
37028616	6	75	from	performance	1085:1095	arg1	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	75	from	performance	1085:1095	arg1	capacity					1147:1154	thermal storage capacity	1131:1154	thermal storage capacity	1131:1154	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	75	from	performance	1085:1095	arg1	reliability					1168:1178	thermal reliability	1160:1178	thermal reliability	1160:1178	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	2	76	theme	droplets	435:442	arg1	surface					424:430	the surface	420:430	the surface of droplets	420:442	In this study, Pickering emulsion stabilized with chitin nanocrystals (ChNCs) was used to prepare paraffin wax (PW) microcapsules by forming a dense melamine-formaldehyde resin shell on the surface of droplets.					
37028616	6	77	used	used	1194:1197	arg2	reliability					1168:1178	thermal reliability	1160:1178	thermal reliability	1160:1178	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	77	used	used	1194:1197	arg2	terms					1100:1104	terms	1100:1104	terms of thermal conductivity	1100:1128	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
37028616	6	77	used	used	1194:1197	arg2	capacity					1147:1154	thermal storage capacity	1131:1154	thermal storage capacity	1131:1154	In addition, the composite of PW microcapsules/copper foam shows satisfactory performance in terms of thermal conductivity, thermal storage capacity and thermal reliability, which can be used for effective temperature regulation of heat generating materials.					
36787634	3	0	theme	short-chain	737:747	arg1	acid					755:758	short-chain fatty acid	737:758	short-chain fatty acid (SCFAs) production	737:777	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	0	theme	short-chain	737:747	arg1	SCFAs					761:765	SCFAs	761:765	SCFAs	761:765	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	7	1	theme	diferuloyl	1477:1486	arg1	cross-links					1488:1498	diferuloyl cross-links	1477:1498	diferuloyl cross-links	1477:1498	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	7	2	theme	corn	1366:1369	arg1	glucuronoarabinoxylans					1376:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	1	3	from	polysaccharides	170:184	arg1	rich					128:131	rich	128:131	rich	128:131	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	3	4	dep	composition	594:604	arg1	the					575:577	the	575:577	the	575:577	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	6	5	theme	butyric	1209:1215	arg1	acid					1217:1220	butyric acid	1209:1220	increased butyric acid production	1199:1231	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	6	6	theme	increased	1199:1207	arg1	production					1222:1231	increased butyric acid production	1199:1231	increased butyric acid production	1199:1231	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	4	7	theme	in	893:894	arg1	fermentation					902:913	in vitro fermentation	893:913	in vitro fermentation	893:913	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	3	8	from	influence	532:540	arg1	functionality					610:622	functionality	610:622	functionality	610:622	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	8	from	influence	532:540	arg1	composition					594:604	gut microbiome composition	579:604	gut microbiome composition	579:604	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	9	theme	samples	564:570	arg1	influence					532:540	the influence	528:540	the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production	528:777	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	7	10	theme	prebiotic	1416:1424	arg1	candidates					1426:1435	potential prebiotic candidates	1406:1435	potential prebiotic candidates	1406:1435	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	3	11	theme	microbiome	583:592	arg1	composition					594:604	gut microbiome composition	579:604	gut microbiome composition	579:604	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	4	12	theme	FGAX	784:787	arg1	samples					789:795	All FGAX samples	780:795	All FGAX samples	780:795	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	4	13	from	levels	872:877	arg1	composition					829:839	the relative composition	816:839	the relative composition of the microbiota	816:857	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	4	14	theme	SCFA	867:870	arg1	levels					872:877	the SCFA levels	863:877	the SCFA levels after 24 h of in vitro fermentation	863:913	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	3	15	theme	soluble	551:557	arg1	samples					564:570	these soluble FGAX samples	545:570	these soluble FGAX samples	545:570	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	6	16	theme	microbiota	1072:1081	arg1	changes					1083:1089	The microbiota changes	1068:1089	The microbiota changes induced by FGAX-M and FGAX-H	1068:1118	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	3	17	theme	fatty	749:753	arg1	acid					755:758	short-chain fatty acid	737:758	short-chain fatty acid (SCFAs) production	737:777	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	17	theme	fatty	749:753	arg1	SCFAs					761:765	SCFAs	761:765	SCFAs	761:765	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	1	18	from	rich	128:131	arg1	polysaccharides					170:184	substituted glucuronoarabinoxylan polysaccharides	136:184	substituted glucuronoarabinoxylan polysaccharides	136:184	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	2	19	theme	prebiotic	291:299	arg1	activity					301:308	the potential prebiotic activity	277:308	the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	277:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	7	20	theme	solubilized	1326:1336	arg1	glucuronoarabinoxylans					1376:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	7	21	dep	solubilized	1326:1336	arg1	substituted					1339:1349	substituted	1339:1349	substituted	1339:1349	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	3	22	theme	acid	755:758	arg1	production					768:777	short-chain fatty acid (SCFAs) production	737:777	short-chain fatty acid (SCFAs) production	737:777	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	2	23	theme	bran	350:353	arg1	medium					379:384	medium feruloylated	379:397	medium feruloylated (FGAX-M)	379:406	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	23	theme	bran	350:353	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	23	theme	bran	350:353	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	23	theme	bran	350:353	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	24	theme	cross-linked	417:428	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	24	theme	cross-linked	417:428	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	24	theme	cross-linked	417:428	arg1	FGAX-H					438:443	FGAX-H	438:443	FGAX-H	438:443	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	0	25	theme	Soluble	0:6	arg1	Glucuronoarabinoxylans					34:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	7	26	theme	single	1451:1456	arg1	feruloylations					1458:1471	single feruloylations	1451:1471	single feruloylations	1451:1471	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	7	27	theme	arabinoxylan	1543:1554	arg1	compounds					1556:1564	these arabinoxylan compounds	1537:1564	these arabinoxylan compounds	1537:1564	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	2	28	theme	corn	345:348	arg1	medium					379:384	medium feruloylated	379:397	medium feruloylated (FGAX-M)	379:406	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	28	theme	corn	345:348	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	28	theme	corn	345:348	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	28	theme	corn	345:348	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	6	29	from	increase	1139:1146	arg1	abundance					1164:1172	the relative abundance	1151:1172	the relative abundance of Anaerostipes	1151:1188	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	2	30	theme	laccase	409:415	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	30	theme	laccase	409:415	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	30	theme	laccase	409:415	arg1	FGAX-H					438:443	FGAX-H	438:443	FGAX-H	438:443	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	0	31	theme	Corn	24:27	arg1	Glucuronoarabinoxylans					34:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	6	32	theme	acid	1217:1220	arg1	production					1222:1231	increased butyric acid production	1199:1231	increased butyric acid production	1199:1231	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	2	33	theme	solubilized	333:343	arg1	medium					379:384	medium feruloylated	379:397	medium feruloylated (FGAX-M)	379:406	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	33	theme	solubilized	333:343	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	33	theme	solubilized	333:343	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	33	theme	solubilized	333:343	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	4	34	from	changes	805:811	arg1	composition					829:839	the relative composition	816:839	the relative composition of the microbiota	816:857	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	2	35	theme	alkali-treated	451:464	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	35	theme	alkali-treated	451:464	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	35	theme	alkali-treated	451:464	arg1	FGAX-B					507:512	FGAX-B	507:512	FGAX-B	507:512	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	7	36	theme	compounds	1556:1564	arg1	potential					1524:1532	the prebiotic potential	1510:1532	the prebiotic potential of these arabinoxylan compounds	1510:1564	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	2	37	theme	devoid	473:478	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	37	theme	devoid	473:478	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	37	theme	devoid	473:478	arg1	FGAX-B					507:512	FGAX-B	507:512	FGAX-B	507:512	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	38	link	cross-linked	417:428	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	38	link	cross-linked	417:428	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	38	link	cross-linked	417:428	arg1	FGAX-H					438:443	FGAX-H	438:443	FGAX-H	438:443	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	3	39	theme	gut	579:581	arg1	composition					594:604	gut microbiome composition	579:604	gut microbiome composition	579:604	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	4	40	dep	in	893:894	arg1	vitro					896:900	vitro	896:900	vitro	896:900	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	3	41	theme	production	768:777	arg1	assessment					723:732	assessment	723:732	assessment of short-chain fatty acid (SCFAs) production	723:777	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	41	theme	production	768:777	arg1	sequencing					708:717	rRNA gene amplicon sequencing	689:717	rRNA gene amplicon sequencing	689:717	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	FGAX-M					430:435	laccase cross-linked FGAX-M	409:435	laccase cross-linked FGAX-M (FGAX-H)	409:444	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	FGAX-M					466:471	alkali-treated FGAX-M	451:471	alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	451:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	FGAX-M					400:405	FGAX-M	400:405	FGAX-M	400:405	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	FGAX-H					438:443	FGAX-H	438:443	FGAX-H	438:443	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	medium					379:384	medium feruloylated	379:397	medium feruloylated (FGAX-M)	379:406	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	42	dep	glucuronoarabinoxylans	355:376	arg1	FGAX-B					507:512	FGAX-B	507:512	FGAX-B	507:512	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	4	43	theme	relative	820:827	arg1	composition					829:839	the relative composition	816:839	the relative composition of the microbiota	816:857	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	3	44	dep	in	631:632	arg1	vitro					634:638	vitro	634:638	vitro	634:638	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	1	45	theme	diferulic	234:242	arg1	moieties					249:256	diferulic acid moieties	234:256	diferulic acid moieties	234:256	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	0	46	theme	Bran	29:32	arg1	Glucuronoarabinoxylans					34:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans	0:55	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	7	47	theme	potential	1406:1414	arg1	candidates					1426:1435	potential prebiotic candidates	1406:1435	potential prebiotic candidates	1406:1435	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	3	48	theme	in	631:632	arg1	fermentations					656:668	in vitro simulated colon fermentations	631:668	in vitro simulated colon fermentations	631:668	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	1	49	theme	acid	244:247	arg1	moieties					249:256	diferulic acid moieties	234:256	diferulic acid moieties	234:256	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	2	50	theme	substitutions	492:504	arg1	devoid					473:478	devoid	473:478	devoid	473:478	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	4	51	theme	fermentation	902:913	arg1	h					888:888	24 h	885:888	24 h of in vitro fermentation	885:913	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	7	52	theme	bran	1371:1374	arg1	glucuronoarabinoxylans					1376:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	2	53	theme	feruloylated	386:397	arg1	medium					379:384	medium feruloylated	379:397	medium feruloylated (FGAX-M)	379:406	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	53	theme	feruloylated	386:397	arg1	FGAX-M					400:405	FGAX-M	400:405	FGAX-M	400:405	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	53	theme	feruloylated	386:397	arg1	glucuronoarabinoxylans					355:376	three enzymatically solubilized corn bran glucuronoarabinoxylans	313:376	three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	313:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	2	54	theme	feruloyl	483:490	arg1	substitutions					492:504	feruloyl substitutions	483:504	feruloyl substitutions	483:504	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	3	55	theme	amplicon	699:706	arg1	sequencing					708:717	rRNA gene amplicon sequencing	689:717	rRNA gene amplicon sequencing	689:717	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	4	56	theme	microbiota	848:857	arg1	composition					829:839	the relative composition	816:839	the relative composition of the microbiota	816:857	All FGAX samples induced changes in the relative composition of the microbiota and the SCFA levels after 24 h of in vitro fermentation.					
36787634	6	57	theme	FGAX-B	1267:1272	arg1	sample					1274:1279	the FGAX-B sample	1263:1279	the FGAX-B sample	1263:1279	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	3	58	theme	simulated	640:648	arg1	fermentations					656:668	in vitro simulated colon fermentations	631:668	in vitro simulated colon fermentations	631:668	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	59	theme	colon	650:654	arg1	fermentations					656:668	in vitro simulated colon fermentations	631:668	in vitro simulated colon fermentations	631:668	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	2	60	theme	potential	281:289	arg1	activity					301:308	the potential prebiotic activity	277:308	the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	277:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	7	61	theme	prebiotic	1514:1522	arg1	potential					1524:1532	the prebiotic potential	1510:1532	the prebiotic potential of these arabinoxylan compounds	1510:1564	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	1	62	theme	Corn	101:104	arg1	bran					106:109	Corn bran	101:109	Corn bran	101:109	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	3	63	theme	FGAX	559:562	arg1	samples					564:570	these soluble FGAX samples	545:570	these soluble FGAX samples	545:570	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	3	64	theme	rRNA	689:692	arg1	sequencing					708:717	rRNA gene amplicon sequencing	689:717	rRNA gene amplicon sequencing	689:717	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	6	65	theme	Anaerostipes	1177:1188	arg1	abundance					1164:1172	the relative abundance	1151:1172	the relative abundance of Anaerostipes	1151:1188	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	2	66	theme	glucuronoarabinoxylans	355:376	arg1	activity					301:308	the potential prebiotic activity	277:308	the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B)	277:513	Here, we assessed the potential prebiotic activity of three enzymatically solubilized corn bran glucuronoarabinoxylans: medium feruloylated (FGAX-M), laccase cross-linked FGAX-M (FGAX-H), and alkali-treated FGAX-M devoid of feruloyl substitutions (FGAX-B).					
36787634	0	67	theme	Gut	76:78	arg1	Microbiota					80:89	the Human Gut Microbiota	66:89	the Human Gut Microbiota	66:89	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	3	68	theme	gene	694:697	arg1	sequencing					708:717	rRNA gene amplicon sequencing	689:717	rRNA gene amplicon sequencing	689:717	We examined the influence of these soluble FGAX samples on the gut microbiome composition and functionality during in vitro simulated colon fermentations, determined by 16S rRNA gene amplicon sequencing and assessment of short-chain fatty acid (SCFAs) production.					
36787634	6	69	theme	relative	1155:1162	arg1	abundance					1164:1172	the relative abundance	1151:1172	the relative abundance of Anaerostipes	1151:1188	The microbiota changes induced by FGAX-M and FGAX-H correlated with an increase in the relative abundance of Anaerostipes and with increased butyric acid production, while the changes induced by the FGAX-B sample were less compelling.					
36787634	1	70	theme	substituted	136:146	arg1	polysaccharides					170:184	substituted glucuronoarabinoxylan polysaccharides	136:184	substituted glucuronoarabinoxylan polysaccharides	136:184	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
36787634	0	71	theme	Human	70:74	arg1	Microbiota					80:89	the Human Gut Microbiota	66:89	the Human Gut Microbiota	66:89	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	7	72	theme	diferuloylated	1351:1364	arg1	glucuronoarabinoxylans					1376:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans	1326:1397	The results imply that solubilized, substituted diferuloylated corn bran glucuronoarabinoxylans may be potential prebiotic candidates and that both single feruloylations and diferuloyl cross-links influence the prebiotic potential of these arabinoxylan compounds.					
36787634	0	73	dep	Soluble	0:6	arg1	Diferuloylated					9:22	Diferuloylated	9:22	Diferuloylated	9:22	Soluble, Diferuloylated Corn Bran Glucuronoarabinoxylans Modulate the Human Gut Microbiota In Vitro.					
36787634	1	74	theme	glucuronoarabinoxylan	148:168	arg1	polysaccharides					170:184	substituted glucuronoarabinoxylan polysaccharides	136:184	substituted glucuronoarabinoxylan polysaccharides	136:184	Corn bran is exceptionally rich in substituted glucuronoarabinoxylan polysaccharides, which are monoferuloylated and cross-linked by diferulic acid moieties.					
37338687	14	0	theme	sodium	1343:1348	arg1	alginate					1350:1357	sodium alginate	1343:1357	sodium alginate	1343:1357	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	7	1	theme	ammonia	494:500	arg1	NH3-N					512:516	NH3-N	512:516	NH3-N	512:516	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	7	1	theme	ammonia	494:500	arg1	nitrogen					502:509	significantly reduced ammonia nitrogen	472:509	significantly reduced ammonia nitrogen (NH3-N)	472:517	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	16	2	from	NH3-N	1574:1578	arg1	wastewater					1612:1621	monosodium glutamate wastewater	1591:1621	monosodium glutamate wastewater	1591:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	13	3	theme	hydrogen	1241:1248	arg1	bonds					1250:1254	intermolecular hydrogen bonds	1226:1254	intermolecular hydrogen bonds	1226:1254	form intermolecular hydrogen bonds.					
37338687	8	4	theme	microspheres	606:617	arg1	conditions					592:601	The optimum preparation conditions	568:601	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater	568:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	11	5	theme	other	1106:1110	arg1	methods					1112:1118	other methods	1106:1118	other methods	1106:1118	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	7	6	theme	monosodium	435:444	arg1	glutamate					446:454	monosodium glutamate	435:454	monosodium glutamate wastewater	435:465	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	4	7	theme	Lignocellulose/montmorillonite	178:207	arg1	composite					209:217	Lignocellulose/montmorillonite composite	178:217	Lignocellulose/montmorillonite composite	178:217	Lignocellulose/montmorillonite composite was selected as the carrier.					
37338687	4	7	theme	Lignocellulose/montmorillonite	178:207	arg1	carrier					239:245	the carrier	235:245	the carrier	235:245	Lignocellulose/montmorillonite composite was selected as the carrier.					
37338687	6	8	theme	microorganism	373:385	arg1	techniques					387:396	immobilized microorganism techniques	361:396	immobilized microorganism techniques	361:396	/calcium alginate microspheres were prepared by immobilized microorganism techniques.					
37338687	2	9	theme	Bacillus	113:120	arg1	sp					122:123	Bacillus sp	113:123	Bacillus sp	113:123	A group of Bacillus sp.					
37338687	16	10	theme	monosodium	1591:1600	arg1	glutamate					1602:1610	monosodium glutamate	1591:1610	monosodium glutamate wastewater	1591:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	8	11	theme	glutamate	667:675	arg1	wastewater					677:686	monosodium glutamate wastewater	656:686	monosodium glutamate wastewater	656:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	10	12	theme	COD	918:920	arg1	capacities					894:903	the removal capacities	882:903	the removal capacities of NH3-N and COD	882:920	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	10	12	theme	COD	918:920	arg1	44832					927:931	44832	927:931	44832	927:931	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	13	13	theme	intermolecular	1226:1239	arg1	bonds					1250:1254	intermolecular hydrogen bonds	1226:1254	intermolecular hydrogen bonds	1226:1254	form intermolecular hydrogen bonds.					
37338687	10	14	theme	NH3-N	908:912	arg1	capacities					894:903	the removal capacities	882:903	the removal capacities of NH3-N and COD	882:920	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	10	14	theme	NH3-N	908:912	arg1	44832					927:931	44832	927:931	44832	927:931	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	7	15	theme	oxygen	532:537	arg1	demand					539:544	chemical oxygen demand	523:544	chemical oxygen demand (COD)	523:550	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	7	15	theme	oxygen	532:537	arg1	COD					547:549	COD	547:549	COD	547:549	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	8	16	from	microspheres	606:617	arg1	treatment					626:634	the treatment	622:634	the treatment of NH3-N and COD of monosodium glutamate wastewater	622:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	7	17	theme	chemical	523:530	arg1	demand					539:544	chemical oxygen demand	523:544	chemical oxygen demand (COD)	523:550	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	7	17	theme	chemical	523:530	arg1	COD					547:549	COD	547:549	COD	547:549	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	3	18	theme	monosodium	145:154	arg1	wastewater					166:175	monosodium glutamate wastewater	145:175	monosodium glutamate wastewater	145:175	was extracted from monosodium glutamate wastewater.					
37338687	6	19	theme	alginate	322:329	arg1	microspheres					331:342	/calcium alginate microspheres	313:342	/calcium alginate microspheres	313:342	/calcium alginate microspheres were prepared by immobilized microorganism techniques.					
37338687	1	20	theme	glutamate	80:88	arg1	wastewater					90:99	monosodium glutamate wastewater	69:99	monosodium glutamate wastewater	69:99	on monosodium glutamate wastewater.					
37338687	7	21	theme	demand	539:544	arg1	concentrations					552:565	significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations	472:565	significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations	472:565	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	12	22	from	-OH	1197:1199	arg1	lignocellulose/montmorillonite					1158:1187	lignocellulose/montmorillonite	1158:1187	lignocellulose/montmorillonite	1158:1187	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	12	22	from	-OH	1197:1199	arg1	sp					1217:1218	the Bacillus sp	1204:1218	the Bacillus sp	1204:1218	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	16	23	theme	NH3-N	1574:1578	arg1	treatment					1561:1569	the treatment	1557:1569	the treatment of NH3-N and COD in monosodium glutamate wastewater	1557:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	10	24	theme	2.0	842:844	arg1	wt					846:847	wt	846:847	wt	846:847	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	11	25	theme	group	1014:1018	arg1	change					1020:1025	functional group change	1003:1025	functional group change	1003:1025	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	9	26	theme	alginate	730:737	arg1	concentration					706:718	The concentration	702:718	The concentration of sodium alginate	702:737	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	9	26	theme	alginate	730:737	arg1	%					749:749	2.0 wt%	743:749	2.0 wt%	743:749	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	16	27	theme	COD	1584:1586	arg1	treatment					1561:1569	the treatment	1557:1569	the treatment of NH3-N and COD in monosodium glutamate wastewater	1557:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	15	28	theme	New	1360:1362	arg1	structures					1372:1381	New crystal structures	1360:1381	New crystal structures	1360:1381	New crystal structures appear inside the material after crosslinking, and the microspheres was formed.					
37338687	0	29	theme	lignocellulose/montmorillonite	10:39	arg1	Effect					0:5	Effect	0:5	Effect of lignocellulose/montmorillonite	0:39	Effect of lignocellulose/montmorillonite immobilized Bacillus sp.					
37338687	5	30	theme	Bacillus	301:308	arg1	sp					310:311	Bacillus sp	301:311	immobilized Bacillus sp	289:311	Lignocellulose/montmorillonite composite immobilized Bacillus sp.					
37338687	17	31	from	NH3-N	1697:1701	arg1	wastewater					1717:1726	industrial wastewater	1706:1726	industrial wastewater	1706:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	9	32	theme	2.0	743:745	arg1	wt					747:748	wt	747:748	wt	747:748	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	0	33	theme	Bacillus	53:60	arg1	sp					62:63	Bacillus sp	53:63	Bacillus sp	53:63	Effect of lignocellulose/montmorillonite immobilized Bacillus sp.					
37338687	11	34	theme	crystal	1032:1038	arg1	structure					1040:1048	crystal structure	1032:1048	crystal structure	1032:1048	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	10	35	theme	coagulation	851:861	arg1	time					863:866	coagulation time	851:866	coagulation time	851:866	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	17	36	from	COD	1689:1691	arg1	wastewater					1717:1726	industrial wastewater	1706:1726	industrial wastewater	1706:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	17	37	from	removal	1678:1684	arg1	wastewater					1717:1726	industrial wastewater	1706:1726	industrial wastewater	1706:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	7	38	theme	nitrogen	502:509	arg1	concentrations					552:565	significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations	472:565	significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations	472:565	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	8	39	theme	preparation	580:590	arg1	conditions					592:601	The optimum preparation conditions	568:601	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater	568:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	7	40	theme	reduced	486:492	arg1	NH3-N					512:516	NH3-N	512:516	NH3-N	512:516	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	7	40	theme	reduced	486:492	arg1	nitrogen					502:509	significantly reduced ammonia nitrogen	472:509	significantly reduced ammonia nitrogen (NH3-N)	472:517	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	11	41	theme	element	986:992	arg1	content					994:1000	element content	986:1000	element content	986:1000	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	17	42	theme	bio-physicochemical	1752:1770	arg1	processes					1772:1780	bio-physicochemical processes	1752:1780	bio-physicochemical processes	1752:1780	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	9	43	theme	Bacillus	797:804	arg1	%					794:794	0.06 wt%	787:794	0.06 wt%	787:794	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	9	43	theme	Bacillus	797:804	arg1	sp					806:807	Bacillus sp	797:807	Bacillus sp	797:807	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	2	44	theme	sp	122:123	arg1	group					104:108	A group	102:108	A group of Bacillus sp	102:123	A group of Bacillus sp.					
37338687	2	44	theme	sp	122:123	arg1	sp					122:123	Bacillus sp	113:123	Bacillus sp	113:123	A group of Bacillus sp.					
37338687	14	45	theme	sodium	1328:1333	arg1	ions					1335:1338	sodium ions	1328:1338	sodium ions in sodium alginate	1328:1357	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	7	46	theme	glutamate	446:454	arg1	wastewater					456:465	monosodium glutamate wastewater	435:465	monosodium glutamate wastewater	435:465	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	6	47	theme	/calcium	313:320	arg1	microspheres					331:342	/calcium alginate microspheres	313:342	/calcium alginate microspheres	313:342	/calcium alginate microspheres were prepared by immobilized microorganism techniques.					
37338687	8	48	from	conditions	592:601	arg1	treatment					626:634	the treatment	622:634	the treatment of NH3-N and COD of monosodium glutamate wastewater	622:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	8	49	theme	NH3-N	639:643	arg1	treatment					626:634	the treatment	622:634	the treatment of NH3-N and COD of monosodium glutamate wastewater	622:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	8	50	theme	COD	649:651	arg1	treatment					626:634	the treatment	622:634	the treatment of NH3-N and COD of monosodium glutamate wastewater	622:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	14	51	theme	Al-O	1270:1273	arg1	bonds					1275:1279	The Si-O and Al-O bonds	1257:1279	The Si-O and Al-O bonds in lignocellulose/montmorillonite	1257:1313	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	8	52	theme	monosodium	656:665	arg1	glutamate					667:675	monosodium glutamate	656:675	monosodium glutamate wastewater	656:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	10	53	theme	removal	886:892	arg1	capacities					894:903	the removal capacities	882:903	the removal capacities of NH3-N and COD	882:920	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	10	53	theme	removal	886:892	arg1	44832					927:931	44832	927:931	44832	927:931	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	14	54	theme	Si-O	1261:1264	arg1	bonds					1275:1279	The Si-O and Al-O bonds	1257:1279	The Si-O and Al-O bonds in lignocellulose/montmorillonite	1257:1313	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	14	55	from	bonds	1275:1279	arg1	lignocellulose/montmorillonite					1284:1313	lignocellulose/montmorillonite	1284:1313	lignocellulose/montmorillonite	1284:1313	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	16	56	theme	glutamate	1602:1610	arg1	wastewater					1612:1621	monosodium glutamate wastewater	1591:1621	monosodium glutamate wastewater	1591:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	8	57	theme	wastewater	677:686	arg1	NH3-N					639:643	NH3-N	639:643	NH3-N	639:643	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	8	57	theme	wastewater	677:686	arg1	COD					649:651	COD	649:651	COD	649:651	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	11	58	theme	microspheres	1057:1068	arg1	change					1020:1025	functional group change	1003:1025	functional group change	1003:1025	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	11	58	theme	microspheres	1057:1068	arg1	content					994:1000	element content	986:1000	element content	986:1000	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	11	58	theme	microspheres	1057:1068	arg1	structure					975:983	surface structure	967:983	surface structure	967:983	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	11	58	theme	microspheres	1057:1068	arg1	structure					1040:1048	crystal structure	1032:1048	crystal structure	1032:1048	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	12	59	from	-COOH	1149:1153	arg1	lignocellulose/montmorillonite					1158:1187	lignocellulose/montmorillonite	1158:1187	lignocellulose/montmorillonite	1158:1187	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	12	59	from	-COOH	1149:1153	arg1	sp					1217:1218	the Bacillus sp	1204:1218	the Bacillus sp	1204:1218	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	8	60	from	treatment	626:634	arg1	conditions					592:601	The optimum preparation conditions	568:601	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater	568:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	6	61	theme	immobilized	361:371	arg1	techniques					387:396	immobilized microorganism techniques	361:396	immobilized microorganism techniques	361:396	/calcium alginate microspheres were prepared by immobilized microorganism techniques.					
37338687	17	62	theme	NH3-N	1697:1701	arg1	removal					1678:1684	the removal	1674:1684	the removal of COD and NH3-N in industrial wastewater	1674:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	3	63	theme	glutamate	156:164	arg1	wastewater					166:175	monosodium glutamate wastewater	145:175	monosodium glutamate wastewater	145:175	was extracted from monosodium glutamate wastewater.					
37338687	10	64	theme	1.0	814:816	arg1	wt					818:819	wt	818:819	wt	818:819	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	17	65	theme	industrial	1706:1715	arg1	wastewater					1717:1726	industrial wastewater	1706:1726	industrial wastewater	1706:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	14	66	from	ions	1335:1338	arg1	alginate					1350:1357	sodium alginate	1343:1357	sodium alginate	1343:1357	The Si-O and Al-O bonds in lignocellulose/montmorillonite reacted with sodium ions in sodium alginate.					
37338687	12	67	dep	showed	1133:1138	arg1	-OH					1197:1199	the -OH	1193:1199	the -OH in the Bacillus sp	1193:1218	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	12	67	dep	showed	1133:1138	arg1	-COOH					1149:1153	the -COOH	1145:1153	the -COOH in lignocellulose/montmorillonite	1145:1187	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	7	68	used	used	421:424	arg2	microspheres					403:414	The microspheres	399:414	The microspheres	399:414	The microspheres were used to treat monosodium glutamate wastewater with significantly reduced ammonia nitrogen (NH3-N) and chemical oxygen demand (COD) concentrations.					
37338687	10	69	theme	CaCl2	823:827	arg1	solution					829:836	CaCl2 solution	823:836	CaCl2 solution	823:836	was 1.0 wt%, CaCl2 solution was 2.0 wt%, coagulation time was 12 h, and the removal capacities of NH3-N and COD were 44832 and 78345 mg/L, respectively.					
37338687	1	70	theme	monosodium	69:78	arg1	wastewater					90:99	monosodium glutamate wastewater	69:99	monosodium glutamate wastewater	69:99	on monosodium glutamate wastewater.					
37338687	12	71	theme	Bacillus	1208:1215	arg1	sp					1217:1218	the Bacillus sp	1204:1218	the Bacillus sp	1204:1218	The results showed that the -COOH in lignocellulose/montmorillonite and the -OH in the Bacillus sp.					
37338687	17	72	from	wastewater	1717:1726	arg1	removal					1678:1684	the removal	1674:1684	the removal of COD and NH3-N in industrial wastewater	1674:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	17	73	theme	interesting	1649:1659	arg1	strategy					1661:1668	an interesting strategy	1646:1668	an interesting strategy for the removal of COD and NH3-N in industrial wastewater	1646:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	16	74	from	wastewater	1612:1621	arg1	treatment					1561:1569	the treatment	1557:1569	the treatment of NH3-N and COD in monosodium glutamate wastewater	1557:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	9	75	theme	sodium	723:728	arg1	alginate					730:737	sodium alginate	723:737	sodium alginate	723:737	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	15	76	theme	crystal	1364:1370	arg1	structures					1372:1381	New crystal structures	1360:1381	New crystal structures	1360:1381	New crystal structures appear inside the material after crosslinking, and the microspheres was formed.					
37338687	11	77	theme	functional	1003:1012	arg1	change					1020:1025	functional group change	1003:1025	functional group change	1003:1025	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	17	78	theme	COD	1689:1691	arg1	removal					1678:1684	the removal	1674:1684	the removal of COD and NH3-N in industrial wastewater	1674:1726	This work can provide an interesting strategy for the removal of COD and NH3-N in industrial wastewater by reasonably combining bio-physicochemical processes.					
37338687	11	79	dep	structure	975:983	arg1	The					963:965	The	963:965	The	963:965	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	16	80	from	treatment	1561:1569	arg1	wastewater					1612:1621	monosodium glutamate wastewater	1591:1621	monosodium glutamate wastewater	1591:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
37338687	8	81	theme	optimum	572:578	arg1	conditions					592:601	The optimum preparation conditions	568:601	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater	568:686	The optimum preparation conditions of microspheres in the treatment of NH3-N and COD of monosodium glutamate wastewater were studied.					
37338687	11	82	theme	surface	967:973	arg1	structure					975:983	surface structure	967:983	surface structure	967:983	The surface structure, element content, functional group change, and crystal structure of the microspheres were characterized by SEM, EDS, and other methods.					
37338687	5	83	theme	immobilized	289:299	arg1	sp					310:311	Bacillus sp	301:311	immobilized Bacillus sp	289:311	Lignocellulose/montmorillonite composite immobilized Bacillus sp.					
37338687	9	84	theme	wt	792:793	arg1	%					794:794	0.06 wt%	787:794	0.06 wt%	787:794	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	9	84	theme	wt	792:793	arg1	sp					806:807	Bacillus sp	797:807	Bacillus sp	797:807	The concentration of sodium alginate was 2.0 wt%, lignocellulose/montmorillonite was 0.06 wt%, Bacillus sp.					
37338687	16	85	from	COD	1584:1586	arg1	wastewater					1612:1621	monosodium glutamate wastewater	1591:1621	monosodium glutamate wastewater	1591:1621	Thus, the study has shown that the microspheres were successfully prepared and contributes to the treatment of NH3-N and COD in monosodium glutamate wastewater.					
36586629	3	0	theme	chemical	707:714	arg1	composition					716:726	nano-scale chemical composition	696:726	nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations	696:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	2	1	theme	composition	340:350	arg1	assay					318:322	The conventional wet assay	297:322	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor	297:402	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	8	2	theme	drug	1760:1763	arg1	content					1765:1771	the drug content	1756:1771	the drug content	1756:1771	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	7	3	theme	peak	1537:1540	arg1	ratio					1542:1546	the drug to lactose peak ratio	1517:1546	the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1517:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	4	4	theme	β2-agonist	944:953	arg1	xinafoate					966:974	a long-acting β2-agonist salmeterol xinafoate	930:974	a long-acting β2-agonist salmeterol xinafoate	930:974	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	2	5	from	assay	318:322	arg1	impactor					395:402	a cascade impactor	385:402	a cascade impactor	385:402	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	7	6	theme	significant	1491:1501	arg1	difference					1503:1512	no significant difference	1488:1512	no significant difference	1488:1512	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	9	7	theme	qualitative	1958:1968	arg1	comparable					2009:2018	comparable	2009:2018	comparable	2009:2018	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	9	7	theme	qualitative	1958:1968	arg1	compositions					1979:1990	The qualitative chemical compositions	1954:1990	The qualitative chemical compositions from O-PTIR	1954:2002	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	3	8	theme	pharmaceutical	760:773	arg1	formulations					779:790	pharmaceutical DPI formulations	760:790	pharmaceutical DPI formulations	760:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	1	9	theme	various	267:273	arg1	sizes					275:279	various sizes	267:279	various sizes in solid state	267:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	4	10	theme	corticosteroid	891:904	arg1	propionate					918:927	an inhaled corticosteroid fluticasone propionate	880:927	an inhaled corticosteroid fluticasone propionate	880:927	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	3	11	theme	particles	747:755	arg1	composition					716:726	nano-scale chemical composition	696:726	nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations	696:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	1	12	from	state	290:294	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	3	13	theme	proof-of-concept	547:562	arg1	study					564:568	this proof-of-concept study	542:568	this proof-of-concept study	542:568	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	1	14	theme	drugs	179:183	arg1	distribution					163:174	the distribution	159:174	the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	159:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	6	15	theme	Next	1251:1254	arg1	Generation					1256:1265	a Next Generation Impactor (NGI)	1249:1280	a Next Generation Impactor (NGI)	1249:1280	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	9	16	theme	DPIs	2211:2214	arg1	properties					2197:2206	the physicochemical properties	2177:2206	the physicochemical properties of DPIs	2177:2214	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	6	17	theme	peaks	1330:1334	arg1	presence					1318:1325	the presence	1314:1325	the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1)	1314:1475	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	2	18	theme	conventional	301:312	arg1	assay					318:322	The conventional wet assay	297:322	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor	297:402	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	1	19	theme	excipients	189:198	arg1	distribution					163:174	the distribution	159:174	the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	159:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	8	20	from	stage	1864:1868	arg1	NGI					1855:1857	the NGI	1851:1857	the NGI from stage 1 to stage 7	1851:1881	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	3	21	theme	formulations	779:790	arg1	particles					747:755	size-segregated particles	731:755	size-segregated particles of pharmaceutical DPI formulations	731:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	1	22	theme	pharmaceutical	203:216	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	9	23	theme	conventional	2023:2034	arg1	assays					2049:2054	conventional wet chemical assays	2023:2054	conventional wet chemical assays of various size fractions	2023:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	1	24	from	particles	254:262	arg1	state					290:294	solid state	284:294	solid state	284:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	1	25	theme	powder	222:227	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	7	26	theme	aerosol	1676:1682	arg1	formulation					1684:1694	the aerosol formulation	1672:1694	the aerosol formulation	1672:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	9	27	theme	chemical	2040:2047	arg1	assays					2049:2054	conventional wet chemical assays	2023:2054	conventional wet chemical assays of various size fractions	2023:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	5	28	theme	chronic	1119:1125	arg1	disease					1149:1155	chronic obstructive pulmonary disease	1119:1155	chronic obstructive pulmonary disease	1119:1155	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	1	29	theme	research	124:131	arg1	aim					112:114	The aim	108:114	The aim of this research	108:131	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	3	30	from	aim	574:576	arg1	study					564:568	this proof-of-concept study	542:568	this proof-of-concept study	542:568	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	5	31	theme	pulmonary	1139:1147	arg1	disease					1149:1155	chronic obstructive pulmonary disease	1119:1155	chronic obstructive pulmonary disease	1119:1155	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	7	32	theme	lactose	1653:1659	arg1	content					1661:1667	drug and lactose content	1644:1667	content	1661:1667	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	2	33	theme	complex	513:519	arg1	formulations					525:536	complex DPI formulations	513:536	complex DPI formulations	513:536	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	9	34	theme	size	2067:2070	arg1	fractions					2072:2080	various size fractions	2059:2080	various size fractions	2059:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	0	35	theme	pharmaceutical	72:85	arg1	aerosols					98:105	pharmaceutical dry powder aerosols	72:105	pharmaceutical dry powder aerosols	72:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	3	36	theme	photothermal	626:637	arg1	O-PTIR					662:667	O-PTIR	662:667	O-PTIR	662:667	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	3	36	theme	photothermal	626:637	arg1	spectroscopy					648:659	optical photothermal infrared spectroscopy	618:659	optical photothermal infrared spectroscopy (O-PTIR)	618:668	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	7	37	theme	drug	1644:1647	arg1	content					1661:1667	drug and lactose content	1644:1667	content	1661:1667	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	2	38	theme	particles	500:508	arg1	morphology					461:470	spatially resolved morphology	442:470	spatially resolved morphology	442:470	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	2	38	theme	particles	500:508	arg1	composition					485:495	chemical composition	476:495	chemical composition	476:495	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	7	39	dep	ratio	1542:1546	arg1	to					1526:1527	to	1526:1527	to	1526:1527	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	9	40	theme	solid	2219:2223	arg1	state					2225:2229	solid state	2219:2229	solid state	2219:2229	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	0	41	theme	powder	91:96	arg1	aerosols					98:105	pharmaceutical dry powder aerosols	72:105	pharmaceutical dry powder aerosols	72:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	5	42	theme	salmeterol	1050:1059	arg1	xinafoate					1061:1069	salmeterol xinafoate	1050:1069	salmeterol xinafoate	1050:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	42	theme	salmeterol	1050:1059	arg1	ingredients					1011:1021	The active ingredients	1000:1021	The active ingredients fluticasone propionate and salmeterol xinafoate	1000:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	2	43	from	morphology	461:470	arg1	formulations					525:536	complex DPI formulations	513:536	complex DPI formulations	513:536	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	4	44	theme	spray	829:833	arg1	drying					835:840	spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose	829:997	drying	835:840	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	2	45	theme	cascade	387:393	arg1	impactor					395:402	a cascade impactor	385:402	a cascade impactor	385:402	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	6	46	theme	resolved	1168:1175	arg1	spectra					1184:1190	Spatially resolved O-PTIR spectra	1158:1190	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations	1158:1302	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	2	47	theme	resolved	452:459	arg1	morphology					461:470	spatially resolved morphology	442:470	spatially resolved morphology	442:470	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	0	48	theme	Optical	0:6	arg1	spectroscopy					30:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	1	49	theme	sizes	275:279	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	0	50	theme	infrared	21:28	arg1	spectroscopy					30:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	1	51	theme	solid	284:288	arg1	state					290:294	solid state	284:294	solid state	284:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	9	52	theme	valuable	2134:2141	arg1	platform					2154:2161	a valuable analytical platform	2132:2161	a valuable analytical platform for screening the physicochemical properties of DPIs in solid state	2132:2229	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	7	53	from	homogeneity	1629:1639	arg1	content					1661:1667	drug and lactose content	1644:1667	content	1661:1667	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	7	54	theme	particles	1580:1588	arg1	fractions					1567:1575	various size fractions	1554:1575	various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1554:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	2	55	theme	chemical	331:338	arg1	composition					340:350	the chemical composition	327:350	the chemical composition of particles after collection	327:380	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	8	56	theme	distribution	1940:1951	arg1	ratio					1916:1920	the ratio	1912:1920	the ratio of drug-excipient distribution	1912:1951	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	3	57	theme	nano-scale	696:705	arg1	composition					716:726	nano-scale chemical composition	696:726	nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations	696:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	5	58	used	used	1082:1085	arg2	xinafoate					1061:1069	salmeterol xinafoate	1050:1069	salmeterol xinafoate	1050:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	58	used	used	1082:1085	arg2	propionate					1035:1044	fluticasone propionate	1023:1044	fluticasone propionate	1023:1044	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	58	used	used	1082:1085	arg2	ingredients					1011:1021	The active ingredients	1000:1021	The active ingredients fluticasone propionate and salmeterol xinafoate	1000:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	1	59	theme	inhalation	229:238	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	7	60	theme	various	1554:1560	arg1	fractions					1567:1575	various size fractions	1554:1575	various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1554:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	9	61	theme	physicochemical	2181:2195	arg1	properties					2197:2206	the physicochemical properties	2177:2206	the physicochemical properties of DPIs	2177:2214	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	8	62	theme	suspension-spray	1714:1729	arg1	formulation					1737:1747	the suspension-spray dried formulation	1710:1747	the suspension-spray dried formulation	1710:1747	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	1	63	theme	DPI	241:243	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	3	64	theme	size-segregated	731:745	arg1	particles					747:755	size-segregated particles	731:755	size-segregated particles of pharmaceutical DPI formulations	731:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	1	65	theme	aerosol	246:252	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	7	66	theme	lactose	1529:1535	arg1	ratio					1542:1546	the drug to lactose peak ratio	1517:1546	the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1517:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	1	67	from	sizes	275:279	arg1	state					290:294	solid state	284:294	solid state	284:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	8	68	theme	drug-excipient	1925:1938	arg1	distribution					1940:1951	drug-excipient distribution	1925:1951	drug-excipient distribution	1925:1951	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	6	69	dep	propionate	1359:1368	arg1	1661 cm-1					1393:1401	1661 cm-1	1393:1401	1661 cm-1	1393:1401	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	6	69	dep	propionate	1359:1368	arg1	1702 cm-1					1382:1390	1702 cm-1	1382:1390	1702 cm-1	1382:1390	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	6	69	dep	propionate	1359:1368	arg1	1746 cm-1					1371:1379	1746 cm-1	1371:1379	1746 cm-1	1371:1379	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	6	69	dep	propionate	1359:1368	arg1	1612 cm-1					1407:1415	1612 cm-1	1407:1415	1612 cm-1	1407:1415	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	7	70	theme	drug	1521:1524	arg1	ratio					1542:1546	the drug to lactose peak ratio	1517:1546	the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1517:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	4	71	theme	long-acting	932:942	arg1	xinafoate					966:974	a long-acting β2-agonist salmeterol xinafoate	930:974	a long-acting β2-agonist salmeterol xinafoate	930:974	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	9	72	theme	chemical	1970:1977	arg1	comparable					2009:2018	comparable	2009:2018	comparable	2009:2018	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	9	72	theme	chemical	1970:1977	arg1	compositions					1979:1990	The qualitative chemical compositions	1954:1990	The qualitative chemical compositions from O-PTIR	1954:2002	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	3	73	theme	DPI	775:777	arg1	formulations					779:790	pharmaceutical DPI formulations	760:790	pharmaceutical DPI formulations	760:790	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	6	74	theme	fluticasone	1347:1357	arg1	propionate					1359:1368	fluticasone propionate	1347:1368	fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1)	1347:1416	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	4	75	theme	inhaled	883:889	arg1	propionate					918:927	an inhaled corticosteroid fluticasone propionate	880:927	an inhaled corticosteroid fluticasone propionate	880:927	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	6	76	theme	Generation	1256:1265	arg1	stages					1235:1240	stages 1-7	1235:1244	stages 1-7 of a Next Generation Impactor (NGI)	1235:1280	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	6	77	theme	related	1336:1342	arg1	peaks					1330:1334	peaks	1330:1334	peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1)	1330:1475	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	2	78	theme	wet	314:316	arg1	assay					318:322	The conventional wet assay	297:322	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor	297:402	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	4	79	theme	fluticasone	906:916	arg1	propionate					918:927	an inhaled corticosteroid fluticasone propionate	880:927	an inhaled corticosteroid fluticasone propionate	880:927	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	6	80	theme	salmeterol	1419:1428	arg1	1582 cm-1					1441:1449	1582 cm-1	1441:1449	1582 cm-1	1441:1449	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	6	80	theme	salmeterol	1419:1428	arg1	xinafoate					1430:1438	salmeterol xinafoate	1419:1438	salmeterol xinafoate (1582 cm-1)	1419:1450	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	8	81	theme	lactose	1793:1799	arg1	content					1801:1807	the lactose content	1789:1807	the lactose content	1789:1807	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	4	82	theme	excipient	981:989	arg1	lactose					991:997	excipient lactose	981:997	excipient lactose	981:997	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	6	83	dep	Generation	1256:1265	arg1	NGI					1277:1279	NGI	1277:1279	NGI	1277:1279	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	4	84	dep	drying	835:840	arg1	solution					844:851	a solution	842:851	a solution	842:851	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	1	85	theme	dry	218:220	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	9	86	theme	wet	2036:2038	arg1	assays					2049:2054	conventional wet chemical assays	2023:2054	conventional wet chemical assays of various size fractions	2023:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	4	87	theme	salmeterol	955:964	arg1	xinafoate					966:974	a long-acting β2-agonist salmeterol xinafoate	930:974	a long-acting β2-agonist salmeterol xinafoate	930:974	These formulations were prepared by spray drying a solution or a suspension comprising an inhaled corticosteroid fluticasone propionate, a long-acting β2-agonist salmeterol xinafoate, and excipient lactose.					
36586629	8	88	dep	showed	1749:1754	arg1	increased					1773:1781	increased	1773:1781	showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution	1749:1951	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	5	89	theme	obstructive	1127:1137	arg1	disease					1149:1155	chronic obstructive pulmonary disease	1119:1155	chronic obstructive pulmonary disease	1119:1155	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	3	90	theme	infrared	639:646	arg1	O-PTIR					662:667	O-PTIR	662:667	O-PTIR	662:667	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	3	90	theme	infrared	639:646	arg1	spectroscopy					648:659	optical photothermal infrared spectroscopy	618:659	optical photothermal infrared spectroscopy (O-PTIR)	618:668	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	9	91	from	O-PTIR	1997:2002	arg1	comparable					2009:2018	comparable	2009:2018	comparable	2009:2018	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	9	91	from	O-PTIR	1997:2002	arg1	compositions					1979:1990	The qualitative chemical compositions	1954:1990	The qualitative chemical compositions from O-PTIR	1954:2002	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	9	92	theme	various	2059:2065	arg1	fractions					2072:2080	various size fractions	2059:2080	various size fractions	2059:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	0	93	theme	dry	87:89	arg1	aerosols					98:105	pharmaceutical dry powder aerosols	72:105	pharmaceutical dry powder aerosols	72:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	5	94	theme	disease	1149:1155	arg1	treatment					1095:1103	the treatment	1091:1103	the treatment of asthma and chronic obstructive pulmonary disease	1091:1155	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	3	95	theme	optical	618:624	arg1	O-PTIR					662:667	O-PTIR	662:667	O-PTIR	662:667	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	3	95	theme	optical	618:624	arg1	spectroscopy					648:659	optical photothermal infrared spectroscopy	618:659	optical photothermal infrared spectroscopy (O-PTIR)	618:668	In this proof-of-concept study, we aim to demonstrate the feasibility of using optical photothermal infrared spectroscopy (O-PTIR) to characterize micro- to nano-scale chemical composition of size-segregated particles of pharmaceutical DPI formulations.					
36586629	9	96	theme	fractions	2072:2080	arg1	assays					2049:2054	conventional wet chemical assays	2023:2054	conventional wet chemical assays of various size fractions	2023:2080	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	8	97	from	heterogeneity	1895:1907	arg1	ratio					1916:1920	the ratio	1912:1920	the ratio of drug-excipient distribution	1912:1951	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	0	98	theme	aerosols	98:105	arg1	analysis					60:67	nanochemical analysis	47:67	nanochemical analysis of pharmaceutical dry powder aerosols	47:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	7	99	from	content	1661:1667	arg1	formulation					1684:1694	the aerosol formulation	1672:1694	the aerosol formulation	1672:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	5	100	dep	ingredients	1011:1021	arg1	propionate					1035:1044	fluticasone propionate	1023:1044	fluticasone propionate	1023:1044	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	100	dep	ingredients	1011:1021	arg1	xinafoate					1061:1069	salmeterol xinafoate	1050:1069	salmeterol xinafoate	1050:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	100	dep	ingredients	1011:1021	arg1	ingredients					1011:1021	The active ingredients	1000:1021	The active ingredients fluticasone propionate and salmeterol xinafoate	1000:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	1	101	from	distribution	163:174	arg1	particles					254:262	pharmaceutical dry powder inhalation (DPI) aerosol particles	203:262	pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state	203:294	The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state.					
36586629	6	102	theme	O-PTIR	1177:1182	arg1	spectra					1184:1190	Spatially resolved O-PTIR spectra	1158:1190	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations	1158:1302	Spatially resolved O-PTIR spectra acquired from the particles collected from stages 1-7 of a Next Generation Impactor (NGI) for both formulations confirmed the presence of peaks related to fluticasone propionate (1746 cm-1, 1702 cm-1, 1661 cm-1 and 1612 cm-1), salmeterol xinafoate (1582 cm-1), and lactose (1080 cm-1).					
36586629	2	103	theme	DPI	521:523	arg1	formulations					525:536	complex DPI formulations	513:536	complex DPI formulations	513:536	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	2	104	from	composition	485:495	arg1	formulations					525:536	complex DPI formulations	513:536	complex DPI formulations	513:536	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	9	105	theme	O-PTIR	2113:2118	arg1	suitability					2098:2108	the suitability	2094:2108	the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state	2094:2229	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	0	106	theme	photothermal	8:19	arg1	spectroscopy					30:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy	0:41	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	5	107	theme	active	1004:1009	arg1	propionate					1035:1044	fluticasone propionate	1023:1044	fluticasone propionate	1023:1044	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	107	theme	active	1004:1009	arg1	xinafoate					1061:1069	salmeterol xinafoate	1050:1069	salmeterol xinafoate	1050:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	107	theme	active	1004:1009	arg1	ingredients					1011:1021	The active ingredients	1000:1021	The active ingredients fluticasone propionate and salmeterol xinafoate	1000:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	108	theme	fluticasone	1023:1033	arg1	propionate					1035:1044	fluticasone propionate	1023:1044	fluticasone propionate	1023:1044	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	5	108	theme	fluticasone	1023:1033	arg1	ingredients					1011:1021	The active ingredients	1000:1021	The active ingredients fluticasone propionate and salmeterol xinafoate	1000:1069	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	0	109	theme	nanochemical	47:58	arg1	analysis					60:67	nanochemical analysis	47:67	nanochemical analysis of pharmaceutical dry powder aerosols	47:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	2	110	theme	chemical	476:483	arg1	composition					485:495	chemical composition	476:495	chemical composition	476:495	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
36586629	9	111	theme	analytical	2143:2152	arg1	platform					2154:2161	a valuable analytical platform	2132:2161	a valuable analytical platform for screening the physicochemical properties of DPIs in solid state	2132:2229	The qualitative chemical compositions from O-PTIR were comparable to conventional wet chemical assays of various size fractions, indicating the suitability of O-PTIR to serve as a valuable analytical platform for screening the physicochemical properties of DPIs in solid state.					
36586629	7	112	dep	dried	1596:1600	arg1	spray					1590:1594	spray	1590:1594	spray	1590:1594	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	7	112	dep	dried	1596:1600	arg1	particles					1580:1588	particles	1580:1588	particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1580:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	5	113	theme	asthma	1108:1113	arg1	treatment					1095:1103	the treatment	1091:1103	the treatment of asthma and chronic obstructive pulmonary disease	1091:1155	The active ingredients fluticasone propionate and salmeterol xinafoate are widely used for the treatment of asthma and chronic obstructive pulmonary disease.					
36586629	0	114	dep	spectroscopy	30:41	arg1	analysis					60:67	nanochemical analysis	47:67	nanochemical analysis of pharmaceutical dry powder aerosols	47:105	Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.					
36586629	8	115	theme	dried	1731:1735	arg1	formulation					1737:1747	the suspension-spray dried formulation	1710:1747	the suspension-spray dried formulation	1710:1747	In contrast, the suspension-spray dried formulation showed the drug content increased while the lactose content decreased in the particles collected down the NGI from stage 1 to stage 7, indicating heterogeneity in the ratio of drug-excipient distribution.					
36586629	7	116	theme	size	1562:1565	arg1	fractions					1567:1575	various size fractions	1554:1575	various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation	1554:1694	There was no significant difference in the drug to lactose peak ratio among various size fractions of particles spray dried from solution indicating a homogeneity in drug and lactose content in the aerosol formulation.					
36586629	2	117	theme	particles	355:363	arg1	composition					340:350	the chemical composition	327:350	the chemical composition of particles after collection	327:380	The conventional wet assay of the chemical composition of particles after collection in a cascade impactor lacks the capability to differentiate spatially resolved morphology and chemical composition of particles in complex DPI formulations.					
37328411	0	0	theme	composite	74:82	arg1	film					84:87	composite film	74:87	composite film for acid blue 93 dye adsorption	74:119	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	4	1	from	use	786:788	arg1	environments					799:810	water environments	793:810	water environments	793:810	Furthermore, the composite film displayed substantially enhanced hydrophobicity, making it suitable for use in water environments.					
37328411	2	2	dep	polyvinyl	241:249	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	2	dep	polyvinyl	241:249	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	3	3	theme	FTIR	443:446	arg1	tests					509:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	4	4	theme	enhanced	738:745	arg1	hydrophobicity					747:760	substantially enhanced hydrophobicity	724:760	substantially enhanced hydrophobicity	724:760	Furthermore, the composite film displayed substantially enhanced hydrophobicity, making it suitable for use in water environments.					
37328411	2	5	theme	polyvinyl	241:249	arg1	film					325:328	a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film	239:328	a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film	239:328	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	6	theme	alcohol/chitosan-based	251:272	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	6	theme	alcohol/chitosan-based	251:272	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	5	7	theme	acid	876:879	arg1	adsorption					862:871	stable adsorption	855:871	stable adsorption of acid blue 93 (AB93) at pH 2-9	855:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	7	8	theme	CS-g-CA	1088:1094	arg1	material					1120:1127	a promising material	1108:1127	a promising material for the treatment of organic dye-polluted wastewater	1108:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	7	8	theme	CS-g-CA	1088:1094	arg1	film					1100:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	3	9	theme	contact	468:474	arg1	angle					476:480	contact angle	468:480	contact angle	468:480	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	3	10	theme	mechanical	487:496	arg1	properties					498:507	mechanical properties	487:507	mechanical properties	487:507	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	0	11	theme	blue	98:101	arg1	dye					106:108	acid blue 93 dye	93:108	acid blue 93 dye adsorption	93:119	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	2	12	theme	casting	355:361	arg1	method					363:368	a simple casting method	346:368	a simple casting method to be used in dye adsorption	346:397	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	5	13	theme	blue	881:884	arg1	acid					876:879	acid blue 93 (AB93)	876:894	acid blue 93 (AB93) at pH 2-9	876:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	7	14	theme	dye-polluted	1158:1169	arg1	wastewater					1171:1180	organic dye-polluted wastewater	1150:1180	organic dye-polluted wastewater	1150:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	0	15	theme	acid	93:96	arg1	dye					106:108	acid blue 93 dye	93:108	acid blue 93 dye adsorption	93:119	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	3	16	theme	transparency	454:465	arg1	tests					509:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	1	17	theme	water-insoluble	150:164	arg1	dots					196:199	water-insoluble chitosan-based polymer carbon dots	150:199	water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs)	150:216	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	17	theme	water-insoluble	150:164	arg1	CDs					213:215	P (CS-g-CA)CDs	202:215	P (CS-g-CA)CDs	202:215	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	18	theme	flexible	9:16	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	3	19	theme	hydrogen	613:620	arg1	bonding					622:628	hydrogen bonding	613:628	hydrogen bonding	613:628	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	7	20	theme	CDs	1096:1098	arg1	material					1120:1127	a promising material	1108:1127	a promising material for the treatment of organic dye-polluted wastewater	1108:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	7	20	theme	CDs	1096:1098	arg1	film					1100:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	5	21	theme	stable	855:860	arg1	adsorption					862:871	stable adsorption	855:871	stable adsorption of acid blue 93 (AB93) at pH 2-9	855:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	1	22	theme	chitosan-based	166:179	arg1	dots					196:199	water-insoluble chitosan-based polymer carbon dots	150:199	water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs)	150:216	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	22	theme	chitosan-based	166:179	arg1	CDs					213:215	P (CS-g-CA)CDs	202:215	P (CS-g-CA)CDs	202:215	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	23	theme	Reusable	0:7	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	2	24	theme	carbon	282:287	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	24	theme	carbon	282:287	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	1	25	theme	polymer	181:187	arg1	dots					196:199	water-insoluble chitosan-based polymer carbon dots	150:199	water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs)	150:216	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	25	theme	polymer	181:187	arg1	CDs					213:215	P (CS-g-CA)CDs	202:215	P (CS-g-CA)CDs	202:215	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	26	theme	dye	106:108	arg1	adsorption					110:119	acid blue 93 dye adsorption	93:119	acid blue 93 dye adsorption	93:119	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	2	27	theme	polymer	274:280	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	27	theme	polymer	274:280	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	1	28	theme	carbon	189:194	arg1	dots					196:199	water-insoluble chitosan-based polymer carbon dots	150:199	water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs)	150:216	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	28	theme	carbon	189:194	arg1	CDs					213:215	P (CS-g-CA)CDs	202:215	P (CS-g-CA)CDs	202:215	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	29	theme	poly	18:21	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	1	30	dep	design	126:131	arg1	The					122:124	The	122:124	The	122:124	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	5	31	from	pH	899:900	arg1	acid					876:879	acid blue 93 (AB93)	876:894	acid blue 93 (AB93) at pH 2-9	876:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	5	31	from	pH	899:900	arg1	adsorption					862:871	stable adsorption	855:871	stable adsorption of acid blue 93 (AB93) at pH 2-9	855:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	1	32	theme	dots	196:199	arg1	design					126:131	design	126:131	design	126:131	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	32	theme	dots	196:199	arg1	synthesis					137:145	synthesis	137:145	synthesis	137:145	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	33	theme	alcohol	30:36	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	3	34	theme	mechanical	643:652	arg1	properties					654:663	the mechanical properties	639:663	the mechanical properties of the PVA film	639:679	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	7	35	theme	organic	1150:1156	arg1	wastewater					1171:1180	organic dye-polluted wastewater	1150:1180	organic dye-polluted wastewater	1150:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	2	36	theme	simple	348:353	arg1	method					363:368	a simple casting method	346:368	a simple casting method to be used in dye adsorption	346:397	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	0	37	theme	vinyl	24:28	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	3	38	theme	film	676:679	arg1	properties					654:663	the mechanical properties	639:663	the mechanical properties of the PVA film	639:679	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	5	39	theme	mg/g	954:957	arg1	capacity					935:942	an enhanced adsorption capacity	912:942	an enhanced adsorption capacity of 433.24 mg/g	912:957	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	1	40	theme	P	202:202	arg1	dots					196:199	water-insoluble chitosan-based polymer carbon dots	150:199	water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs)	150:216	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	1	40	theme	P	202:202	arg1	CDs					213:215	P (CS-g-CA)CDs	202:215	P (CS-g-CA)CDs	202:215	The design and synthesis of water-insoluble chitosan-based polymer carbon dots (P (CS-g-CA)CDs) are described.					
37328411	0	41	theme	/chitosan-based	38:52	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	3	42	theme	P	561:561	arg1	CDs					572:574	P (CS-g-CA)CDs	561:574	P (CS-g-CA)CDs	561:574	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	3	43	theme	properties	498:507	arg1	tests					509:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	2	44	theme	CS-g-CA	302:308	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	44	theme	CS-g-CA	302:308	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	45	theme	dye	384:386	arg1	adsorption					388:397	dye adsorption	384:397	dye adsorption	384:397	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	6	46	theme	%	1040:1040	arg1	efficiency					1011:1020	an efficiency	1008:1020	an efficiency of greater than 89%	1008:1040	The adsorption obeyed the Langmuir law and with an efficiency of greater than 89% even after five cycles.					
37328411	4	47	theme	water	793:797	arg1	environments					799:810	water environments	793:810	water environments	793:810	Furthermore, the composite film displayed substantially enhanced hydrophobicity, making it suitable for use in water environments.					
37328411	7	48	theme	wastewater	1171:1180	arg1	treatment					1137:1145	the treatment	1133:1145	the treatment of organic dye-polluted wastewater	1133:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	7	49	theme	promising	1110:1118	arg1	material					1120:1127	a promising material	1108:1127	a promising material for the treatment of organic dye-polluted wastewater	1108:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	7	49	theme	promising	1110:1118	arg1	film					1100:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	3	50	theme	PVA	672:674	arg1	film					676:679	the PVA film	668:679	the PVA film	668:679	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	5	51	theme	enhanced	915:922	arg1	capacity					935:942	an enhanced adsorption capacity	912:942	an enhanced adsorption capacity of 433.24 mg/g	912:957	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	3	52	theme	successful	533:542	arg1	incorporation					544:556	the successful incorporation	529:556	the successful incorporation of P (CS-g-CA)CDs into the film	529:588	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	2	53	theme	PVA/P	295:299	arg1	CDs					310:312	PVA/P (CS-g-CA)CDs	295:312	PVA/P (CS-g-CA)CDs	295:312	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	2	53	theme	PVA/P	295:299	arg1	dots					289:292	alcohol/chitosan-based polymer carbon dots	251:292	alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs)	251:313	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	3	54	theme	angle	476:480	arg1	tests					509:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	5	55	theme	adsorption	924:933	arg1	capacity					935:942	an enhanced adsorption capacity	912:942	an enhanced adsorption capacity of 433.24 mg/g	912:957	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	5	56	theme	composite	830:838	arg1	film					840:843	the composite film	826:843	the composite film	826:843	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	3	57	theme	composite	404:412	arg1	film					414:417	The composite film	400:417	The composite film	400:417	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	7	58	theme	PVA/P	1081:1085	arg1	material					1120:1127	a promising material	1108:1127	a promising material for the treatment of organic dye-polluted wastewater	1108:1180	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	7	58	theme	PVA/P	1081:1085	arg1	film					1100:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	the PVA/P (CS-g-CA)CDs film	1077:1103	Therefore, the PVA/P (CS-g-CA)CDs film is a promising material for the treatment of organic dye-polluted wastewater.					
37328411	3	59	theme	CDs	572:574	arg1	incorporation					544:556	the successful incorporation	529:556	the successful incorporation of P (CS-g-CA)CDs into the film	529:588	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37328411	4	60	theme	composite	699:707	arg1	film					709:712	the composite film	695:712	the composite film	695:712	Furthermore, the composite film displayed substantially enhanced hydrophobicity, making it suitable for use in water environments.					
37328411	2	61	theme	composite	315:323	arg1	film					325:328	a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film	239:328	a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film	239:328	Then, a polyvinyl alcohol/chitosan-based polymer carbon dots (PVA/P (CS-g-CA)CDs) composite film was prepared by a simple casting method to be used in dye adsorption.					
37328411	5	62	from	adsorption	862:871	arg1	pH					899:900	pH 2-9	899:904	pH 2-9	899:904	In addition, the composite film exhibited stable adsorption of acid blue 93 (AB93) at pH 2-9, with an enhanced adsorption capacity of 433.24 mg/g.					
37328411	0	63	theme	polymer	54:60	arg1	carbon					62:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon	0:67	Reusable flexible poly (vinyl alcohol)/chitosan-based polymer carbon dots composite film for acid blue 93 dye adsorption.					
37328411	6	64	theme	Langmuir	986:993	arg1	law					995:997	the Langmuir law	982:997	the Langmuir law	982:997	The adsorption obeyed the Langmuir law and with an efficiency of greater than 89% even after five cycles.					
37328411	3	65	theme	XPS	449:451	arg1	tests					509:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	FTIR, XPS, transparency, contact angle, and mechanical properties tests	443:513	The composite film was characterized using FTIR, XPS, transparency, contact angle, and mechanical properties tests, which showed the successful incorporation of P (CS-g-CA)CDs into the film and also revealed that hydrogen bonding improved the mechanical properties of the PVA film.					
37316048	12	0	theme	kinetic	1910:1916	arg1	parameters					1918:1927	kinetic parameters	1910:1927	kinetic parameters	1910:1927	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	6	1	theme	starch	875:880	arg1	content					882:888	a starch content	873:888	a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%	873:947	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	6	2	theme	dry	1003:1005	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	12	3	theme	digestibility	2041:2053	arg1	predictive					2008:2017	predictive	2008:2017	predictive	2008:2017	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	6	4	theme	Jack	800:803	arg1	collections					810:820	Jack bean collections	800:820	Jack bean collections	800:820	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	2	5	theme	bean	317:320	arg1	utilization					297:307	the utilization	293:307	the utilization of Jack bean	293:320	However, the utilization of Jack bean is limited due to the long cooking time to achieve palatable softness.					
37316048	4	6	theme	optimal	553:559	arg1	times					569:573	different optimal cooking times	543:573	different optimal cooking times	543:573	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	11	7	theme	starch	1737:1742	arg1	kinetics					1725:1732	The digestion kinetics	1711:1732	The digestion kinetics of starch	1711:1742	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	12	8	theme	optimal	1885:1891	arg1	time					1901:1904	optimal cooking time	1885:1904	optimal cooking time	1885:1904	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	13	9	theme	reduced	2093:2099	arg1	times					2109:2113	reduced cooking times	2093:2113	reduced cooking times	2093:2113	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	4	10	theme	microstructure	616:629	arg1	terms					578:582	terms	578:582	terms of their proximate composition, microstructure and protein and starch digestibility	578:666	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	0	11	with	bean	105:108	arg1	times					164:168	different optimal cooking times	138:168	different optimal cooking times	138:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	7	12	theme	representative	1081:1094	arg1	sizes					1027:1031	Particle sizes	1018:1031	Particle sizes ranging between 125 and 250 µm	1018:1062	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	7	12	theme	representative	1081:1094	arg1	sample					1096:1101	a representative sample	1079:1101	a representative sample of the whole bean	1079:1119	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	12	13	theme	cooking	1988:1994	arg1	time					1996:1999	optimal cooking time	1980:1999	optimal cooking time	1980:1999	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	9	14	dep	123 µm	1471:1476	arg1	to					1468:1469	to	1468:1469	to	1468:1469	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	10	15	theme	starch	1647:1652	arg1	digestibility					1666:1678	the starch and protein digestibility	1643:1678	the starch and protein digestibility in the Jack beans collections	1643:1708	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	12	16	theme	optimal	1980:1986	arg1	time					1996:1999	optimal cooking time	1980:1999	optimal cooking time	1980:1999	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	1	17	theme	high	186:189	arg1	content					199:205	its high protein content	182:205	its high protein content	182:205	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	12	18	theme	starch	1944:1949	arg1	digestibility					1951:1963	starch digestibility	1944:1963	starch digestibility	1944:1963	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	11	19	theme	logistic	1755:1762	arg1	model					1764:1768	a logistic model	1753:1768	a logistic model	1753:1768	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	4	20	theme	composition	603:613	arg1	terms					578:582	terms	578:582	terms of their proximate composition, microstructure and protein and starch digestibility	578:666	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	11	21	theme	conversion	1835:1844	arg1	model					1846:1850	a fractional conversion model	1822:1850	a fractional conversion model	1822:1850	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	1	22	theme	content	199:205	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	22	theme	content	199:205	arg1	source					276:281	a promising alternative protein source	244:281	a promising alternative protein source	244:281	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	8	23	theme	bean	1353:1356	arg1	cells					1358:1362	kidney bean cells	1346:1362	kidney bean cells	1346:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	12	24	theme	digestibility	1951:1963	arg1	time					1901:1904	optimal cooking time	1885:1904	optimal cooking time	1885:1904	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	12	24	theme	digestibility	1951:1963	arg1	parameters					1918:1927	kinetic parameters	1910:1927	kinetic parameters	1910:1927	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	10	25	theme	protein	1658:1664	arg1	digestibility					1666:1678	the starch and protein digestibility	1643:1678	the starch and protein digestibility in the Jack beans collections	1643:1708	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	9	26	theme	bean	1386:1389	arg1	cells					1391:1395	Jack bean cells	1381:1395	Jack bean cells	1381:1395	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	6	27	dep	41	909:910	arg1	to					906:907	to	906:907	to	906:907	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	15	28	from	protein	2387:2393	arg1	understanding					2337:2349	our understanding	2333:2349	our understanding of the effect of food processing on protein and starch digestibility in legumes	2333:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	15	28	from	protein	2387:2393	arg1	legumes					2423:2429	legumes	2423:2429	legumes	2423:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	0	29	theme	optimal	148:154	arg1	times					164:168	different optimal cooking times	138:168	different optimal cooking times	138:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	13	30	theme	Jack	2158:2161	arg1	collection					2168:2177	one Jack bean collection	2154:2177	one Jack bean collection	2154:2177	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	3	31	theme	cooking	417:423	arg1	time					425:428	the cooking time	413:428	the cooking time	413:428	We hypothesize that the cooking time may influence protein and starch digestibility.					
37316048	4	32	theme	starch	647:652	arg1	digestibility					654:666	starch digestibility	647:666	starch digestibility	647:666	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	0	33	theme	starch	55:60	arg1	digestibility					62:74	starch digestibility	55:74	starch digestibility	55:74	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	10	34	theme	Jack	1687:1690	arg1	collections					1698:1708	the Jack beans collections	1683:1708	the Jack beans collections	1683:1708	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	13	35	theme	cooking	2101:2107	arg1	times					2109:2113	reduced cooking times	2093:2113	reduced cooking times	2093:2113	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	6	36	contain	have	822:825	arg2	content					882:888	a starch content	873:888	a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%	873:947	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	6	36	contain	have	822:825	arg2	content					837:843	a protein content	827:843	a protein content ranging from 28.8 to 39.3%	827:870	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	6	36	contain	have	822:825	arg1	collections					810:820	Jack bean collections	800:820	Jack bean collections	800:820	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	6	36	contain	have	822:825	arg2	content					971:977	a concanavalin A content	954:977	a concanavalin A content in the range 35-51 mg/g dry cotyledon	954:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	13	37	theme	starch	2130:2135	arg1	digestibility					2137:2149	starch digestibility	2130:2149	starch digestibility	2130:2149	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	8	38	contain	have	1259:1262	arg2	shape					1272:1276	an oval shape	1264:1276	an oval shape	1264:1276	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	8	38	contain	have	1259:1262	arg1	cells					1253:1257	Jack bean cells	1243:1257	Jack bean cells	1243:1257	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	0	39	theme	collections	85:95	arg1	microstructure					23:36	microstructure	23:36	microstructure	23:36	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	0	39	theme	collections	85:95	arg1	protein					43:49	protein	43:49	protein	43:49	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	0	39	theme	collections	85:95	arg1	composition					10:20	Proximate composition	0:20	Proximate composition	0:20	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	0	39	theme	collections	85:95	arg1	digestibility					62:74	starch digestibility	55:74	starch digestibility	55:74	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	15	40	from	understanding	2337:2349	arg1	protein					2387:2393	protein	2387:2393	protein	2387:2393	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	15	40	from	understanding	2337:2349	arg1	digestibility					2406:2418	starch digestibility	2399:2418	starch digestibility	2399:2418	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	15	41	theme	starch	2399:2404	arg1	digestibility					2406:2418	starch digestibility	2399:2418	starch digestibility	2399:2418	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	9	42	theme	CLSM	1431:1434	arg1	micrographs					1436:1446	CLSM micrographs	1431:1446	CLSM micrographs	1431:1446	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	10	43	from	digestibility	1666:1678	arg1	collections					1698:1708	the Jack beans collections	1683:1708	the Jack beans collections	1683:1708	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	6	44	theme	fiber	916:920	arg1	%					911:911	31 to 41%	903:911	31 to 41%	903:911	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	6	44	theme	fiber	916:920	arg1	content					922:928	a fiber content	914:928	a fiber content	914:928	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	2	45	theme	cooking	349:355	arg1	time					357:360	the long cooking time	340:360	the long cooking time to achieve palatable softness	340:390	However, the utilization of Jack bean is limited due to the long cooking time to achieve palatable softness.					
37316048	0	46	theme	Jack	100:103	arg1	ensiformis					121:130	Canavalia ensiformis	111:130	Canavalia ensiformis	111:130	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	0	46	theme	Jack	100:103	arg1	bean					105:108	Jack bean	100:108	Jack bean (Canavalia ensiformis) with different optimal cooking times	100:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	13	47	theme	times	2109:2113	arg1	effect					2083:2088	the effect	2079:2088	the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection	2079:2177	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	0	48	theme	Proximate	0:8	arg1	composition					10:20	Proximate composition	0:20	Proximate composition	0:20	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	15	49	theme	processing	2373:2382	arg1	effect					2358:2363	the effect	2354:2363	the effect of food processing on protein and starch digestibility in legumes	2354:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	2	50	theme	palatable	373:381	arg1	softness					383:390	palatable softness	373:390	palatable softness	373:390	However, the utilization of Jack bean is limited due to the long cooking time to achieve palatable softness.					
37316048	9	51	dep	31-38 µm	1521:1528	arg1	diameter					1489:1496	the diameter	1485:1496	the diameter of starch granules	1485:1515	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	9	51	dep	31-38 µm	1521:1528	arg1	larger					1545:1550	larger	1545:1550	larger	1545:1550	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	9	51	dep	31-38 µm	1521:1528	arg1	31-38 µm					1521:1528	31-38 µm	1521:1528	31-38 µm	1521:1528	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	1	52	theme	alternative	256:266	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	52	theme	alternative	256:266	arg1	source					276:281	a promising alternative protein source	244:281	a promising alternative protein source	244:281	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	6	53	theme	concanavalin	956:967	arg1	content					971:977	a concanavalin A content	954:977	a concanavalin A content in the range 35-51 mg/g dry cotyledon	954:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	4	54	theme	Jack	516:519	arg1	collections					526:536	seven Jack bean collections	510:536	seven Jack bean collections	510:536	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	11	55	theme	digestion	1783:1791	arg1	kinetics					1793:1800	the digestion kinetics	1779:1800	the digestion kinetics of protein	1779:1811	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	2	56	theme	Jack	312:315	arg1	bean					317:320	Jack bean	312:320	Jack bean	312:320	However, the utilization of Jack bean is limited due to the long cooking time to achieve palatable softness.					
37316048	6	57	theme	Proximate	766:774	arg1	composition					776:786	Proximate composition	766:786	Proximate composition	766:786	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	8	58	theme	protein	1320:1326	arg1	matrix					1328:1333	a protein matrix	1318:1333	a protein matrix similar to kidney bean cells	1318:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	7	59	theme	collections	1183:1193	arg1	digestibility					1156:1168	digestibility	1156:1168	digestibility	1156:1168	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	7	59	theme	collections	1183:1193	arg1	microstructure					1137:1150	microstructure	1137:1150	microstructure	1137:1150	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	4	60	theme	cooking	561:567	arg1	times					569:573	different optimal cooking times	543:573	different optimal cooking times	543:573	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	8	61	theme	similar	1335:1341	arg1	matrix					1328:1333	a protein matrix	1318:1333	a protein matrix similar to kidney bean cells	1318:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	10	62	theme	intact	1607:1612	arg1	cells					1614:1618	Isolated intact cells	1598:1618	Isolated intact cells	1598:1618	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	12	63	theme	cooking	1893:1899	arg1	time					1901:1904	optimal cooking time	1885:1904	optimal cooking time	1885:1904	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	9	64	theme	granules	1508:1515	arg1	larger					1545:1550	larger	1545:1550	larger	1545:1550	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	9	64	theme	granules	1508:1515	arg1	diameter					1489:1496	the diameter	1485:1496	the diameter of starch granules	1485:1515	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	9	64	theme	granules	1508:1515	arg1	31-38 µm					1521:1528	31-38 µm	1521:1528	31-38 µm	1521:1528	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	6	65	from	content	882:888	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	3	66	theme	starch	456:461	arg1	digestibility					463:475	starch digestibility	456:475	starch digestibility	456:475	We hypothesize that the cooking time may influence protein and starch digestibility.					
37316048	1	67	theme	Canavalia	219:227	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	67	theme	Canavalia	219:227	arg1	ensiformis					229:238	Canavalia ensiformis	219:238	Canavalia ensiformis	219:238	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	6	68	theme	35-51 mg/g	992:1001	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	7	69	theme	Particle	1018:1025	arg1	sizes					1027:1031	Particle sizes	1018:1031	Particle sizes ranging between 125 and 250 µm	1018:1062	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	7	69	theme	Particle	1018:1025	arg1	sample					1096:1101	a representative sample	1079:1101	a representative sample of the whole bean	1079:1119	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	6	70	from	content	971:977	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	10	71	used	used	1625:1628	arg2	cells					1614:1618	Isolated intact cells	1598:1618	Isolated intact cells	1598:1618	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	8	72	theme	Jack	1243:1246	arg1	cells					1253:1257	Jack bean cells	1243:1257	Jack bean cells	1243:1257	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	4	73	theme	different	543:551	arg1	times					569:573	different optimal cooking times	543:573	different optimal cooking times	543:573	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	14	74	theme	starch	2247:2252	arg1	digestibility					2254:2266	starch digestibility	2247:2266	starch digestibility	2247:2266	The result showed that reducing cooking time significantly reduces starch digestibility, but not protein digestibility.					
37316048	8	75	from	embedded	1306:1313	arg1	matrix					1328:1333	a protein matrix	1318:1333	a protein matrix similar to kidney bean cells	1318:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	6	76	from	content	837:843	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	0	77	theme	Canavalia	111:119	arg1	ensiformis					121:130	Canavalia ensiformis	111:130	Canavalia ensiformis	111:130	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	0	77	theme	Canavalia	111:119	arg1	bean					105:108	Jack bean	100:108	Jack bean (Canavalia ensiformis) with different optimal cooking times	100:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	14	78	theme	cooking	2212:2218	arg1	time					2220:2223	cooking time	2212:2223	cooking time	2212:2223	The result showed that reducing cooking time significantly reduces starch digestibility, but not protein digestibility.					
37316048	8	79	from	matrix	1328:1333	arg1	embedded					1306:1313	embedded	1306:1313	embedded	1306:1313	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	13	80	theme	bean	2163:2166	arg1	collection					2168:2177	one Jack bean collection	2154:2177	one Jack bean collection	2154:2177	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	9	81	theme	kidney	1569:1574	arg1	bean					1576:1579	the kidney bean starch granules	1565:1595	the kidney bean starch granules	1565:1595	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	8	82	theme	kidney	1346:1351	arg1	cells					1358:1362	kidney bean cells	1346:1362	kidney bean cells	1346:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	12	83	theme	protein	1932:1938	arg1	time					1901:1904	optimal cooking time	1885:1904	optimal cooking time	1885:1904	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	12	83	theme	protein	1932:1938	arg1	parameters					1918:1927	kinetic parameters	1910:1927	kinetic parameters	1910:1927	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	15	84	from	effect	2358:2363	arg1	protein					2387:2393	protein	2387:2393	protein	2387:2393	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	15	84	from	effect	2358:2363	arg1	digestibility					2406:2418	starch digestibility	2399:2418	starch digestibility	2399:2418	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	11	85	theme	fractional	1824:1833	arg1	model					1846:1850	a fractional conversion model	1822:1850	a fractional conversion model	1822:1850	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	1	86	theme	protein	191:197	arg1	content					199:205	its high protein content	182:205	its high protein content	182:205	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	9	87	theme	starch	1581:1586	arg1	granules					1588:1595	starch granules	1581:1595	the kidney bean starch granules	1565:1595	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	4	88	theme	proximate	593:601	arg1	composition					603:613	their proximate composition	587:613	their proximate composition	587:613	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	0	89	theme	different	138:146	arg1	times					164:168	different optimal cooking times	138:168	different optimal cooking times	138:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	15	90	theme	food	2368:2371	arg1	processing					2373:2382	food processing	2368:2382	food processing	2368:2382	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	9	91	theme	Jack	1381:1384	arg1	cells					1391:1395	Jack bean cells	1381:1395	Jack bean cells	1381:1395	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	5	92	theme	Kidney	669:674	arg1	reference					699:707	a reference	697:707	a reference for microstructure and protein and starch digestibility	697:763	Kidney bean was included as a reference for microstructure and protein and starch digestibility.					
37316048	5	92	theme	Kidney	669:674	arg1	bean					676:679	Kidney bean	669:679	Kidney bean	669:679	Kidney bean was included as a reference for microstructure and protein and starch digestibility.					
37316048	8	93	theme	laser	1205:1209	arg1	CLSM					1223:1226	CLSM	1223:1226	CLSM	1223:1226	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	8	93	theme	laser	1205:1209	arg1	microscopy					1211:1220	Confocal laser microscopy	1196:1220	Confocal laser microscopy (CLSM)	1196:1227	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	0	94	theme	cooking	156:162	arg1	times					164:168	different optimal cooking times	138:168	different optimal cooking times	138:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	15	95	theme	effect	2358:2363	arg1	understanding					2337:2349	our understanding	2333:2349	our understanding of the effect of food processing on protein and starch digestibility in legumes	2333:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	9	96	theme	cells	1391:1395	arg1	diameter					1369:1376	The diameter	1365:1376	The diameter of Jack bean cells	1365:1395	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	9	97	dep	bean	1576:1579	arg1	granules					1588:1595	starch granules	1581:1595	the kidney bean starch granules	1565:1595	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	10	98	theme	beans	1692:1696	arg1	collections					1698:1708	the Jack beans collections	1683:1708	the Jack beans collections	1683:1708	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37316048	8	99	contain	contain	1282:1288	arg1	cells					1253:1257	Jack bean cells	1243:1257	Jack bean cells	1243:1257	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	8	99	contain	contain	1282:1288	arg2	granules					1297:1304	starch granules	1290:1304	starch granules embedded in a protein matrix similar to kidney bean cells	1290:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	15	100	from	digestibility	2406:2418	arg1	understanding					2337:2349	our understanding	2333:2349	our understanding of the effect of food processing on protein and starch digestibility in legumes	2333:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	15	100	from	digestibility	2406:2418	arg1	legumes					2423:2429	legumes	2423:2429	legumes	2423:2429	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	7	101	theme	whole	1110:1114	arg1	bean					1116:1119	the whole bean	1106:1119	the whole bean	1106:1119	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	7	102	theme	bean	1116:1119	arg1	sizes					1027:1031	Particle sizes	1018:1031	Particle sizes ranging between 125 and 250 µm	1018:1062	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	7	102	theme	bean	1116:1119	arg1	sample					1096:1101	a representative sample	1079:1101	a representative sample of the whole bean	1079:1119	Particle sizes ranging between 125 and 250 µm were chosen as a representative sample of the whole bean to characterize microstructure and digestibility of the seven collections.					
37316048	9	103	theme	image	1413:1417	arg1	analysis					1419:1426	image analysis	1413:1426	image analysis of CLSM micrographs	1413:1446	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	13	104	from	effect	2083:2088	arg1	collection					2168:2177	one Jack bean collection	2154:2177	one Jack bean collection	2154:2177	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	13	104	from	effect	2083:2088	arg1	digestibility					2137:2149	starch digestibility	2130:2149	starch digestibility	2130:2149	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	13	104	from	effect	2083:2088	arg1	protein					2118:2124	protein	2118:2124	protein	2118:2124	In addition, we tested the effect of reduced cooking times on protein and starch digestibility on one Jack bean collection.					
37316048	4	105	theme	digestibility	654:666	arg1	terms					578:582	terms	578:582	terms of their proximate composition, microstructure and protein and starch digestibility	578:666	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	15	106	theme	present	2304:2310	arg1	study					2312:2316	The present study	2300:2316	The present study	2300:2316	The present study contributes to our understanding of the effect of food processing on protein and starch digestibility in legumes.					
37316048	6	107	dep	24.6	943:946	arg1	to					940:941	to	940:941	to	940:941	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	8	108	theme	bean	1248:1251	arg1	cells					1253:1257	Jack bean cells	1243:1257	Jack bean cells	1243:1257	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	0	109	theme	bean	105:108	arg1	collections					85:95	seven collections	79:95	seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times	79:168	Proximate composition, microstructure, and protein and starch digestibility of seven collections of Jack bean (Canavalia ensiformis) with different optimal cooking times.					
37316048	9	110	theme	micrographs	1436:1446	arg1	analysis					1419:1426	image analysis	1413:1426	image analysis of CLSM micrographs	1413:1446	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	6	111	theme	range	986:990	arg1	cotyledon					1007:1015	the range 35-51 mg/g dry cotyledon	982:1015	the range 35-51 mg/g dry cotyledon	982:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	2	112	theme	long	344:347	arg1	time					357:360	the long cooking time	340:360	the long cooking time to achieve palatable softness	340:390	However, the utilization of Jack bean is limited due to the long cooking time to achieve palatable softness.					
37316048	8	113	theme	oval	1267:1270	arg1	shape					1272:1276	an oval shape	1264:1276	an oval shape	1264:1276	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	1	114	theme	promising	246:254	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	114	theme	promising	246:254	arg1	source					276:281	a promising alternative protein source	244:281	a promising alternative protein source	244:281	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	6	115	theme	A	969:969	arg1	content					971:977	a concanavalin A content	954:977	a concanavalin A content in the range 35-51 mg/g dry cotyledon	954:1015	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	4	116	theme	bean	521:524	arg1	collections					526:536	seven Jack bean collections	510:536	seven Jack bean collections	510:536	In this study, we characterized seven Jack bean collections with different optimal cooking times in terms of their proximate composition, microstructure and protein and starch digestibility.					
37316048	11	117	theme	protein	1805:1811	arg1	kinetics					1793:1800	the digestion kinetics	1779:1800	the digestion kinetics of protein	1779:1811	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	5	118	theme	starch	744:749	arg1	digestibility					751:763	starch digestibility	744:763	starch digestibility	744:763	Kidney bean was included as a reference for microstructure and protein and starch digestibility.					
37316048	1	119	theme	protein	268:274	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	119	theme	protein	268:274	arg1	source					276:281	a promising alternative protein source	244:281	a promising alternative protein source	244:281	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	8	120	theme	Confocal	1196:1203	arg1	CLSM					1223:1226	CLSM	1223:1226	CLSM	1223:1226	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	8	120	theme	Confocal	1196:1203	arg1	microscopy					1211:1220	Confocal laser microscopy	1196:1220	Confocal laser microscopy (CLSM)	1196:1227	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	8	121	theme	starch	1290:1295	arg1	granules					1297:1304	starch granules	1290:1304	starch granules embedded in a protein matrix similar to kidney bean cells	1290:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	6	122	theme	protein	829:835	arg1	content					837:843	a protein content	827:843	a protein content ranging from 28.8 to 39.3%	827:870	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	8	123	theme	embedded	1306:1313	arg1	granules					1297:1304	starch granules	1290:1304	starch granules embedded in a protein matrix similar to kidney bean cells	1290:1362	Confocal laser microscopy (CLSM) revealed that Jack bean cells have an oval shape and contain starch granules embedded in a protein matrix similar to kidney bean cells.					
37316048	12	124	theme	protein	2022:2028	arg1	predictive					2008:2017	predictive	2008:2017	predictive	2008:2017	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	11	125	theme	digestion	1715:1723	arg1	kinetics					1725:1732	The digestion kinetics	1711:1732	The digestion kinetics of starch	1711:1742	The digestion kinetics of starch followed a logistic model, whereas the digestion kinetics of protein followed a fractional conversion model.					
37316048	1	126	theme	Jack	208:211	arg1	bean					213:216	Jack bean	208:216	Jack bean (Canavalia ensiformis)	208:239	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	126	theme	Jack	208:211	arg1	ensiformis					229:238	Canavalia ensiformis	219:238	Canavalia ensiformis	219:238	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	1	126	theme	Jack	208:211	arg1	source					276:281	a promising alternative protein source	244:281	a promising alternative protein source	244:281	Because of its high protein content, Jack bean (Canavalia ensiformis) is a promising alternative protein source.					
37316048	6	127	theme	bean	805:808	arg1	collections					810:820	Jack bean collections	800:820	Jack bean collections	800:820	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	9	128	theme	starch	1501:1506	arg1	granules					1508:1515	starch granules	1501:1515	starch granules	1501:1515	The diameter of Jack bean cells was measured by image analysis of CLSM micrographs and ranged from 103 to 123 µm, while the diameter of starch granules was 31-38 µm, comparatively larger than that of the kidney bean starch granules.					
37316048	6	129	dep	%	870:870	arg1	to					863:864	to	863:864	to	863:864	Proximate composition showed that Jack bean collections have a protein content ranging from 28.8 to 39.3%, a starch content ranging from 31 to 41%, a fiber content from 15.4 to 24.6%, and a concanavalin A content in the range 35-51 mg/g dry cotyledon.					
37316048	12	130	theme	starch	2034:2039	arg1	digestibility					2041:2053	starch digestibility	2034:2053	starch digestibility	2034:2053	We found no correlation between optimal cooking time and kinetic parameters of protein and starch digestibility, implying that optimal cooking time is not predictive of protein and starch digestibility.					
37316048	14	131	theme	protein	2277:2283	arg1	digestibility					2285:2297	protein digestibility	2277:2297	protein digestibility	2277:2297	The result showed that reducing cooking time significantly reduces starch digestibility, but not protein digestibility.					
37316048	10	132	theme	Isolated	1598:1605	arg1	cells					1614:1618	Isolated intact cells	1598:1618	Isolated intact cells	1598:1618	Isolated intact cells were used to determine the starch and protein digestibility in the Jack beans collections.					
37160765	1	0	from	influence	257:265	arg1	bioavailability					321:335	the bioavailability	317:335	the bioavailability of valsartan	317:348	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	9	1	theme	hydrogen	1016:1023	arg1	bonding					1025:1031	hydrogen bonding	1016:1031	hydrogen bonding between valsartan and SBE7-β-CD	1016:1063	FTIR suggests hydrogen bonding between valsartan and SBE7-β-CD.					
37160765	13	2	theme	bioavailability	1327:1341	arg1	reference					1452:1460	a reference	1450:1460	a reference standard	1450:1469	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	13	2	theme	bioavailability	1327:1341	arg1	studies					1343:1349	oral bioavailability studies	1322:1349	oral bioavailability studies in rats with tablet formulation F3	1322:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	1	3	theme	ether	281:285	arg1	SBE7-β-CD					303:311	SBE7-β-CD	303:311	SBE7-β-CD	303:311	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	1	3	theme	ether	281:285	arg1	β-cyclodextrin					287:300	sulfobutyl ether β-cyclodextrin	270:300	sulfobutyl ether β-cyclodextrin (SBE7-β-CD)	270:312	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	14	4	theme	Cmax	1550:1553	arg1	values					1529:1534	significantly higher values	1508:1534	significantly higher values of AUC0-∞ and Cmax	1508:1553	The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference.					
37160765	14	5	theme	AUC0-∞	1539:1544	arg1	values					1529:1534	significantly higher values	1508:1534	significantly higher values of AUC0-∞ and Cmax	1508:1553	The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference.					
37160765	15	6	theme	dosage	1669:1674	arg1	form					1676:1679	tablet dosage form	1662:1679	tablet dosage form	1662:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	11	7	theme	SBE7-β-CD	1152:1160	arg1	complex					1162:1168	the prepared SBE7-β-CD complex	1139:1168	the prepared SBE7-β-CD complex using microwave irradiation	1139:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	0	8	theme	Central	145:151	arg1	Design					168:173	a Central Composite Face Design	143:173	a Central Composite Face Design for Optimising Process Parameters	143:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	1	9	theme	study	229:233	arg1	purpose					214:220	The purpose	210:220	The purpose of the study	210:233	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	4	10	theme	Inclusion	493:501	arg1	complexes					503:511	Inclusion complexes	493:511	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio	493:555	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	8	11	from	crystalline	967:977	arg1	formation					901:909	the formation	897:909	the formation of inclusion complexes	897:932	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	8	11	from	crystalline	967:977	arg1	transition					949:958	the drug's transition	938:958	the drug's transition from a crystalline to an amorphous state	938:999	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	0	12	theme	Face	163:166	arg1	Design					168:173	a Central Composite Face Design	143:173	a Central Composite Face Design for Optimising Process Parameters	143:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	12	13	theme	inclusion	1241:1249	arg1	complex					1251:1257	The inclusion complex	1237:1257	The inclusion complex	1237:1257	The inclusion complex was formulated into tablet dosage forms F1 to F4.					
37160765	0	14	theme	Process	190:196	arg1	Parameters					198:207	Optimising Process Parameters	179:207	Optimising Process Parameters	179:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	8	15	theme	complexes	924:932	arg1	formation					901:909	the formation	897:909	the formation of inclusion complexes	897:932	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	8	15	theme	complexes	924:932	arg1	transition					949:958	the drug's transition	938:958	the drug's transition from a crystalline to an amorphous state	938:999	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	14	16	theme	tablet	1479:1484	arg1	formulation					1486:1496	The F3 tablet formulation	1472:1496	The F3 tablet formulation	1472:1496	The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference.					
37160765	6	17	theme	contour	711:717	arg1	plots					719:723	contour plots	711:723	contour plots	711:723	Response surface graphs and contour plots showed how process factors affected drug content.					
37160765	13	18	theme	Diovan®	1432:1438	arg1	tablet					1440:1445	the marketed Diovan® tablet	1419:1445	the marketed Diovan® tablet	1419:1445	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	12	19	theme	tablet	1279:1284	arg1	forms					1293:1297	tablet dosage forms	1279:1297	tablet dosage forms F1 to F4	1279:1306	The inclusion complex was formulated into tablet dosage forms F1 to F4.					
37160765	5	20	theme	composite	660:668	arg1	design					675:680	a central composite face design	650:680	a central composite face design	650:680	The process parameters were optimised with a central composite face design.					
37160765	6	21	theme	Response	683:690	arg1	graphs					700:705	Response surface graphs	683:705	Response surface graphs	683:705	Response surface graphs and contour plots showed how process factors affected drug content.					
37160765	0	22	theme	Sulfobutyl	105:114	arg1	Ether β-Cyclodextrin					116:135	Sulfobutyl Ether β-Cyclodextrin	105:135	Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters	105:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	4	23	theme	SBE7-β-CD	526:534	arg1	complexes					503:511	Inclusion complexes	493:511	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio	493:555	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	11	24	dep	times	1207:1211	arg1	that					1213:1216	that	1213:1216	that	1213:1216	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	3	25	theme	estimated	412:420	arg1	427 ± 0.32 M-1					477:490	427 ± 0.32 M-1	477:490	427 ± 0.32 M-1	477:490	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	3	25	theme	estimated	412:420	arg1	constant					441:448	The estimated apparent stability constant	408:448	The estimated apparent stability constant for valsartan SBE7-β-CD	408:472	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	4	26	theme	equal	539:543	arg1	ratio					551:555	equal molar ratio	539:555	equal molar ratio	539:555	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	0	27	theme	Inclusion	82:90	arg1	Complex					92:98	a Microwave-Irradiated Inclusion Complex	59:98	a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters	59:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	0	28	theme	Valsartan	15:23	arg1	Bioavailability					30:44	Valsartan Oral Bioavailability	15:44	Valsartan Oral Bioavailability	15:44	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	15	29	theme	tablet	1662:1667	arg1	form					1676:1679	tablet dosage form	1662:1679	tablet dosage form	1662:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	6	30	theme	process	736:742	arg1	factors					744:750	process factors	736:750	process factors	736:750	Response surface graphs and contour plots showed how process factors affected drug content.					
37160765	0	31	theme	Bioavailability	30:44	arg1	Enhancement					0:10	Enhancement	0:10	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.	0:208	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	3	32	theme	valsartan	454:462	arg1	SBE7-β-CD					464:472	valsartan SBE7-β-CD	454:472	valsartan SBE7-β-CD	454:472	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	11	33	theme	pure	1221:1224	arg1	valsartan					1226:1234	pure valsartan	1221:1234	pure valsartan	1221:1234	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	3	34	theme	stability	431:439	arg1	427 ± 0.32 M-1					477:490	427 ± 0.32 M-1	477:490	427 ± 0.32 M-1	477:490	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	3	34	theme	stability	431:439	arg1	constant					441:448	The estimated apparent stability constant	408:448	The estimated apparent stability constant for valsartan SBE7-β-CD	408:472	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	4	35	theme	microwave	574:582	arg1	irradiation					584:594	microwave irradiation	574:594	microwave irradiation technique	574:604	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	0	36	theme	Microwave-Irradiated	61:80	arg1	Complex					92:98	a Microwave-Irradiated Inclusion Complex	59:98	a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters	59:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	1	37	theme	valsartan	340:348	arg1	bioavailability					321:335	the bioavailability	317:335	the bioavailability of valsartan	317:348	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	15	38	theme	inclusion	1629:1637	arg1	approach					1700:1707	a promising approach	1688:1707	a promising approach to increasing valsartan oral bioavailability	1688:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	38	theme	inclusion	1629:1637	arg1	complex					1639:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex	1584:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form	1584:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	2	39	theme	solubility	357:366	arg1	investigations					368:381	Phase solubility investigations	351:381	Phase solubility investigations	351:381	Phase solubility investigations showed an AL type curve.					
37160765	10	40	theme	drug	1088:1091	arg1	morphology					1093:1102	drug morphology	1088:1102	drug morphology	1088:1102	SEM showed changes in drug morphology and shape.					
37160765	13	41	theme	tablet	1364:1369	arg1	F3					1383:1384	tablet formulation F3	1364:1384	tablet formulation F3	1364:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	7	42	theme	process	822:828	arg1	variables					830:838	process variables	822:838	process variables	822:838	The inclusion complexes prepared by optimising process variables are characterised.					
37160765	13	43	theme	oral	1322:1325	arg1	bioavailability					1327:1341	oral bioavailability	1322:1341	oral bioavailability studies in rats with tablet formulation F3	1322:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	15	44	theme	valsartan	1723:1731	arg1	bioavailability					1738:1752	valsartan oral bioavailability	1723:1752	valsartan oral bioavailability	1723:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	2	45	theme	AL	393:394	arg1	curve					401:405	an AL type curve	390:405	an AL type curve	390:405	Phase solubility investigations showed an AL type curve.					
37160765	1	46	theme	sulfobutyl	270:279	arg1	SBE7-β-CD					303:311	SBE7-β-CD	303:311	SBE7-β-CD	303:311	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	1	46	theme	sulfobutyl	270:279	arg1	β-cyclodextrin					287:300	sulfobutyl ether β-cyclodextrin	270:300	sulfobutyl ether β-cyclodextrin (SBE7-β-CD)	270:312	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	15	47	theme	promising	1690:1698	arg1	approach					1700:1707	a promising approach	1688:1707	a promising approach to increasing valsartan oral bioavailability	1688:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	47	theme	promising	1690:1698	arg1	complex					1639:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex	1584:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form	1584:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	0	48	with	Complex	92:98	arg1	Ether β-Cyclodextrin					116:135	Sulfobutyl Ether β-Cyclodextrin	105:135	Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters	105:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	1	49	theme	β-cyclodextrin	287:300	arg1	influence					257:265	the influence	253:265	the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan	253:348	The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan.					
37160765	11	50	theme	complex	1162:1168	arg1	rate					1131:1134	The dissolution rate	1115:1134	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation	1115:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	11	50	theme	complex	1162:1168	arg1	times					1207:1211	2.85 times	1202:1211	2.85 times that of pure valsartan	1202:1234	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	13	51	with	rats	1354:1357	arg1	F3					1383:1384	tablet formulation F3	1364:1384	tablet formulation F3	1364:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	11	52	theme	prepared	1143:1150	arg1	complex					1162:1168	the prepared SBE7-β-CD complex	1139:1168	the prepared SBE7-β-CD complex using microwave irradiation	1139:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	14	53	theme	higher	1522:1527	arg1	values					1529:1534	significantly higher values	1508:1534	significantly higher values of AUC0-∞ and Cmax	1508:1553	The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference.					
37160765	0	54	theme	Composite	153:161	arg1	Design					168:173	a Central Composite Face Design	143:173	a Central Composite Face Design for Optimising Process Parameters	143:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	10	55	from	changes	1077:1083	arg1	shape					1108:1112	shape	1108:1112	shape	1108:1112	SEM showed changes in drug morphology and shape.					
37160765	10	55	from	changes	1077:1083	arg1	morphology					1093:1102	drug morphology	1088:1102	drug morphology	1088:1102	SEM showed changes in drug morphology and shape.					
37160765	4	56	from	complexes	503:511	arg1	ratio					551:555	equal molar ratio	539:555	equal molar ratio	539:555	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	7	57	theme	inclusion	779:787	arg1	complexes					789:797	The inclusion complexes	775:797	The inclusion complexes prepared by optimising process variables	775:838	The inclusion complexes prepared by optimising process variables are characterised.					
37160765	11	58	theme	microwave	1176:1184	arg1	irradiation					1186:1196	microwave irradiation	1176:1196	microwave irradiation	1176:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	4	59	theme	valsartan	516:524	arg1	SBE7-β-CD					526:534	valsartan SBE7-β-CD	516:534	valsartan SBE7-β-CD	516:534	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	0	60	theme	Optimising	179:188	arg1	Parameters					198:207	Optimising Process Parameters	179:207	Optimising Process Parameters	179:207	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	5	61	theme	process	611:617	arg1	parameters					619:628	The process parameters	607:628	The process parameters	607:628	The process parameters were optimised with a central composite face design.					
37160765	13	62	theme	standard	1462:1469	arg1	reference					1452:1460	a reference	1450:1460	a reference standard	1450:1469	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	13	62	theme	standard	1462:1469	arg1	studies					1343:1349	oral bioavailability studies	1322:1349	oral bioavailability studies in rats with tablet formulation F3	1322:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	13	63	theme	marketed	1423:1430	arg1	tablet					1440:1445	the marketed Diovan® tablet	1419:1445	the marketed Diovan® tablet	1419:1445	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	12	64	theme	dosage	1286:1291	arg1	forms					1293:1297	tablet dosage forms	1279:1297	tablet dosage forms F1 to F4	1279:1306	The inclusion complex was formulated into tablet dosage forms F1 to F4.					
37160765	8	65	theme	inclusion	914:922	arg1	complexes					924:932	inclusion complexes	914:932	inclusion complexes	914:932	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	14	66	theme	F3	1476:1477	arg1	formulation					1486:1496	The F3 tablet formulation	1472:1496	The F3 tablet formulation	1472:1496	The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference.					
37160765	12	67	theme	F1	1299:1300	arg1	forms					1293:1297	tablet dosage forms	1279:1297	tablet dosage forms F1 to F4	1279:1306	The inclusion complex was formulated into tablet dosage forms F1 to F4.					
37160765	11	68	theme	dissolution	1119:1129	arg1	rate					1131:1134	The dissolution rate	1115:1134	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation	1115:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	11	68	theme	dissolution	1119:1129	arg1	times					1207:1211	2.85 times	1202:1211	2.85 times that of pure valsartan	1202:1234	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	6	69	theme	surface	692:698	arg1	graphs					700:705	Response surface graphs	683:705	Response surface graphs	683:705	Response surface graphs and contour plots showed how process factors affected drug content.					
37160765	8	70	theme	X-ray	871:875	arg1	diffraction					877:887	X-ray diffraction	871:887	X-ray diffraction	871:887	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	5	71	theme	face	670:673	arg1	design					675:680	a central composite face design	650:680	a central composite face design	650:680	The process parameters were optimised with a central composite face design.					
37160765	4	72	theme	molar	545:549	arg1	ratio					551:555	equal molar ratio	539:555	equal molar ratio	539:555	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	3	73	theme	apparent	422:429	arg1	427 ± 0.32 M-1					477:490	427 ± 0.32 M-1	477:490	427 ± 0.32 M-1	477:490	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	3	73	theme	apparent	422:429	arg1	constant					441:448	The estimated apparent stability constant	408:448	The estimated apparent stability constant for valsartan SBE7-β-CD	408:472	The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M-1.					
37160765	15	74	theme	valsartan	1609:1617	arg1	approach					1700:1707	a promising approach	1688:1707	a promising approach to increasing valsartan oral bioavailability	1688:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	74	theme	valsartan	1609:1617	arg1	complex					1639:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex	1584:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form	1584:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	6	75	theme	drug	761:764	arg1	content					766:772	drug content	761:772	drug content	761:772	Response surface graphs and contour plots showed how process factors affected drug content.					
37160765	0	76	theme	Oral	25:28	arg1	Bioavailability					30:44	Valsartan Oral Bioavailability	15:44	Valsartan Oral Bioavailability	15:44	Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters.					
37160765	5	77	theme	central	652:658	arg1	design					675:680	a central composite face design	650:680	a central composite face design	650:680	The process parameters were optimised with a central composite face design.					
37160765	13	78	theme	formulation	1371:1381	arg1	F3					1383:1384	tablet formulation F3	1364:1384	tablet formulation F3	1364:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	8	79	theme	amorphous	985:993	arg1	state					995:999	an amorphous state	982:999	an amorphous state	982:999	The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug's transition from a crystalline to an amorphous state.					
37160765	13	80	from	studies	1343:1349	arg1	rats					1354:1357	rats	1354:1357	rats with tablet formulation F3	1354:1384	Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard.					
37160765	4	81	theme	irradiation	584:594	arg1	technique					596:604	microwave irradiation technique	574:604	microwave irradiation technique	574:604	Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique.					
37160765	15	82	theme	SBE7-β-CD	1619:1627	arg1	approach					1700:1707	a promising approach	1688:1707	a promising approach to increasing valsartan oral bioavailability	1688:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	82	theme	SBE7-β-CD	1619:1627	arg1	complex					1639:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex	1584:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form	1584:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	83	theme	microwave-irradiated	1588:1607	arg1	approach					1700:1707	a promising approach	1688:1707	a promising approach to increasing valsartan oral bioavailability	1688:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	83	theme	microwave-irradiated	1588:1607	arg1	complex					1639:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex	1584:1645	the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form	1584:1679	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	15	84	theme	oral	1733:1736	arg1	bioavailability					1738:1752	valsartan oral bioavailability	1723:1752	valsartan oral bioavailability	1723:1752	Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.					
37160765	2	85	theme	Phase	351:355	arg1	investigations					368:381	Phase solubility investigations	351:381	Phase solubility investigations	351:381	Phase solubility investigations showed an AL type curve.					
37160765	11	86	theme	valsartan	1226:1234	arg1	rate					1131:1134	The dissolution rate	1115:1134	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation	1115:1196	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	11	86	theme	valsartan	1226:1234	arg1	times					1207:1211	2.85 times	1202:1211	2.85 times that of pure valsartan	1202:1234	The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan.					
37160765	2	87	theme	type	396:399	arg1	curve					401:405	an AL type curve	390:405	an AL type curve	390:405	Phase solubility investigations showed an AL type curve.					
36863669	0	0	theme	nanocrystal	89:99	arg1	films					111:115	humidity-responsive cellulose nanocrystal composite films	59:115	humidity-responsive cellulose nanocrystal composite films	59:115	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	3	1	dep	DESs	706:709	arg1	the					702:704	the	702:704	the	702:704	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	2	theme	eutectic	487:494	arg1	solvents					496:503	an amino acid-based natural deep eutectic solvents	454:503	an amino acid-based natural deep eutectic solvents (NADESs)	454:512	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	2	theme	eutectic	487:494	arg1	NADESs					506:511	NADESs	506:511	NADESs	506:511	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	5	3	theme	water	1183:1187	arg1	capacities					1200:1209	their water absorption capacities	1177:1209	their water absorption capacities	1177:1209	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	0	4	theme	cellulose	79:87	arg1	films					111:115	humidity-responsive cellulose nanocrystal composite films	59:115	humidity-responsive cellulose nanocrystal composite films	59:115	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	5	5	theme	absorption	1189:1198	arg1	capacities					1200:1209	their water absorption capacities	1177:1209	their water absorption capacities	1177:1209	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	3	6	dep	polymers	630:637	arg1	alcohol					650:656	polyvinyl alcohol	640:656	polyvinyl alcohol	640:656	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	6	dep	polymers	630:637	arg1	glycol					672:677	polyethylene glycol	659:677	polyethylene glycol	659:677	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	0	7	theme	films	111:115	arg1	construction					43:54	the construction	39:54	the construction of humidity-responsive cellulose nanocrystal composite films	39:115	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	0	8	from	Research	0:7	arg1	solvents					26:33	deep eutectic solvents	12:33	deep eutectic solvents	12:33	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	4	9	theme	relative	858:865	arg1	humidity					867:874	the relative humidity	854:874	the relative humidity rose from 35 % to 100 %	854:898	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	4	9	theme	relative	858:865	arg1	color					824:828	color	824:828	color	824:828	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	2	10	theme	CNC	300:302	arg1	films					304:308	CNC films	300:308	CNC films	300:308	To overcome the brittleness of CNC films, many researchers have explored functional additives to improve their performance.					
36863669	2	11	theme	films	304:308	arg1	brittleness					285:295	the brittleness	281:295	the brittleness of CNC films	281:308	To overcome the brittleness of CNC films, many researchers have explored functional additives to improve their performance.					
36863669	6	12	theme	CNC	1303:1305	arg1	films					1307:1311	more stable CNC films	1291:1311	more stable CNC films	1291:1311	This allows for the development of more stable CNC films and creates potential for biological applications in the future.					
36863669	0	13	theme	composite	101:109	arg1	films					111:115	humidity-responsive cellulose nanocrystal composite films	59:115	humidity-responsive cellulose nanocrystal composite films	59:115	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	5	14	theme	network	1025:1031	arg1	structure					1033:1041	The hydrogen bond network structure	1007:1041	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs	1007:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	15	theme	composite	1142:1150	arg1	films					1152:1156	the composite films	1138:1156	the composite films	1138:1156	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	6	16	theme	stable	1296:1301	arg1	films					1307:1311	more stable CNC films	1291:1311	more stable CNC films	1291:1311	This allows for the development of more stable CNC films and creates potential for biological applications in the future.					
36863669	3	17	theme	natural	474:480	arg1	solvents					496:503	an amino acid-based natural deep eutectic solvents	454:503	an amino acid-based natural deep eutectic solvents (NADESs)	454:512	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	17	theme	natural	474:480	arg1	NADESs					506:511	NADESs	506:511	NADESs	506:511	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	4	18	dep	%	889:889	arg1	to					891:892	to	891:892	to	891:892	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	5	19	dep	DESs	1076:1079	arg1	the					1072:1074	the	1072:1074	the	1072:1074	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	4	20	dep	humidity	867:874	arg1	rose					876:879	rose	876:879	rose from 35 % to 100 %	876:898	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	3	21	theme	deep	420:423	arg1	solvents					434:441	a new green deep eutectic solvents	408:441	a new green deep eutectic solvents (DESs)	408:448	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	21	theme	deep	420:423	arg1	DESs					444:447	DESs	444:447	DESs	444:447	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	2	22	theme	many	311:314	arg1	researchers					316:326	many researchers	311:326	many researchers	311:326	To overcome the brittleness of CNC films, many researchers have explored functional additives to improve their performance.					
36863669	3	23	theme	eutectic	425:432	arg1	solvents					434:441	a new green deep eutectic solvents	408:441	a new green deep eutectic solvents (DESs)	408:448	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	23	theme	eutectic	425:432	arg1	DESs					444:447	DESs	444:447	DESs	444:447	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	0	24	theme	eutectic	17:24	arg1	solvents					26:33	deep eutectic solvents	12:33	deep eutectic solvents	12:33	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	4	25	theme	CNC/G/NADESs-Arg	767:782	arg1	film					800:803	The CNC/G/NADESs-Arg three-component film	763:803	The CNC/G/NADESs-Arg three-component film	763:803	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	3	26	theme	CNC	535:537	arg1	suspensions					539:549	CNC suspensions	535:549	CNC suspensions for the first time	535:568	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	4	27	dep	changed	816:822	arg1	decreased					984:992	decreased	984:992	decreased to 4.52 GPa	984:1004	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	4	27	dep	changed	816:822	arg1	increased					939:947	increased	939:947	increased to 3.05 %	939:957	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	0	28	theme	deep	12:15	arg1	solvents					26:33	deep eutectic solvents	12:33	deep eutectic solvents	12:33	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	1	29	theme	Photonic	118:125	arg1	materials					135:143	Photonic crystal materials	118:143	Photonic crystal materials	118:143	Photonic crystal materials based on cellulose nanocrystals (CNC), which are environmentally responsive and green, have attracted widespread attention.					
36863669	3	30	theme	new	410:412	arg1	solvents					434:441	a new green deep eutectic solvents	408:441	a new green deep eutectic solvents (DESs)	408:448	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	30	theme	new	410:412	arg1	DESs					444:447	DESs	444:447	DESs	444:447	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	31	theme	deep	482:485	arg1	solvents					496:503	an amino acid-based natural deep eutectic solvents	454:503	an amino acid-based natural deep eutectic solvents (NADESs)	454:512	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	31	theme	deep	482:485	arg1	NADESs					506:511	NADESs	506:511	NADESs	506:511	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	32	dep	molecules	595:603	arg1	sorbitol					616:623	sorbitol	616:623	sorbitol	616:623	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	32	dep	molecules	595:603	arg1	glycerol					606:613	glycerol	606:613	glycerol	606:613	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	33	theme	green	414:418	arg1	solvents					434:441	a new green deep eutectic solvents	408:441	a new green deep eutectic solvents (DESs)	408:448	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	33	theme	green	414:418	arg1	DESs					444:447	DESs	444:447	DESs	444:447	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	34	theme	three-component	730:744	arg1	films					756:760	three-component composite films	730:760	three-component composite films	730:760	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	4	35	theme	100 	894:897	arg1	%					889:889	%	889:889	%	889:889	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	5	36	theme	hydrogen	1011:1018	arg1	structure					1033:1041	The hydrogen bond network structure	1007:1041	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs	1007:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	4	37	theme	three-component	784:798	arg1	film					800:803	The CNC/G/NADESs-Arg three-component film	763:803	The CNC/G/NADESs-Arg three-component film	763:803	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	5	38	theme	mechanical	1113:1122	arg1	properties					1124:1133	the mechanical properties	1109:1133	the mechanical properties of the composite films	1109:1156	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	3	39	theme	composite	746:754	arg1	films					756:760	three-component composite films	730:760	three-component composite films	730:760	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	6	40	theme	films	1307:1311	arg1	development					1276:1286	the development	1272:1286	the development of more stable CNC films	1272:1311	This allows for the development of more stable CNC films and creates potential for biological applications in the future.					
36863669	5	41	theme	bond	1020:1023	arg1	structure					1033:1041	The hydrogen bond network structure	1007:1041	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs	1007:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	3	42	theme	first	559:563	arg1	time					565:568	the first time	555:568	the first time	555:568	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	1	43	theme	crystal	127:133	arg1	materials					135:143	Photonic crystal materials	118:143	Photonic crystal materials	118:143	Photonic crystal materials based on cellulose nanocrystals (CNC), which are environmentally responsive and green, have attracted widespread attention.					
36863669	6	44	theme	biological	1339:1348	arg1	applications					1350:1361	biological applications	1339:1361	biological applications in the future	1339:1375	This allows for the development of more stable CNC films and creates potential for biological applications in the future.					
36863669	5	45	theme	NADESs	1084:1089	arg1	NADESs					1084:1089	NADESs	1084:1089	NADESs	1084:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	45	theme	NADESs	1084:1089	arg1	amounts					1061:1067	trace amounts	1055:1067	trace amounts of the DESs or NADESs	1055:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	45	theme	NADESs	1084:1089	arg1	DESs					1076:1079	DESs	1076:1079	DESs	1076:1079	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	46	theme	trace	1055:1059	arg1	NADESs					1084:1089	NADESs	1084:1089	NADESs	1084:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	46	theme	trace	1055:1059	arg1	amounts					1061:1067	trace amounts	1055:1067	trace amounts of the DESs or NADESs	1055:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	46	theme	trace	1055:1059	arg1	DESs					1076:1079	DESs	1076:1079	DESs	1076:1079	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	6	47	from	applications	1350:1361	arg1	future					1370:1375	future	1370:1375	future	1370:1375	This allows for the development of more stable CNC films and creates potential for biological applications in the future.					
36863669	5	48	theme	DESs	1076:1079	arg1	NADESs					1084:1089	NADESs	1084:1089	NADESs	1084:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	48	theme	DESs	1076:1079	arg1	amounts					1061:1067	trace amounts	1055:1067	trace amounts of the DESs or NADESs	1055:1089	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	5	48	theme	DESs	1076:1079	arg1	DESs					1076:1079	DESs	1076:1079	DESs	1076:1079	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	2	49	theme	functional	342:351	arg1	additives					353:361	functional additives	342:361	functional additives	342:361	To overcome the brittleness of CNC films, many researchers have explored functional additives to improve their performance.					
36863669	4	50	theme	35 	886:888	arg1	%					889:889	%	889:889	%	889:889	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	3	51	theme	polyvinyl	640:648	arg1	alcohol					650:656	polyvinyl alcohol	640:656	polyvinyl alcohol	640:656	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	51	theme	polyvinyl	640:648	arg1	glycol					672:677	polyethylene glycol	659:677	polyethylene glycol	659:677	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	5	52	theme	films	1152:1156	arg1	properties					1124:1133	the mechanical properties	1109:1133	the mechanical properties of the composite films	1109:1156	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	3	53	theme	acid-based	463:472	arg1	solvents					496:503	an amino acid-based natural deep eutectic solvents	454:503	an amino acid-based natural deep eutectic solvents (NADESs)	454:512	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	53	theme	acid-based	463:472	arg1	NADESs					506:511	NADESs	506:511	NADESs	506:511	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	4	54	theme	Young	968:972	arg1	modulus					976:982	the Young's modulus	964:982	the Young's modulus	964:982	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	4	55	from	break	933:937	arg1	elongation					919:928	the elongation	915:928	the elongation at break	915:937	The CNC/G/NADESs-Arg three-component film reversibly changed color from blue to crimson as the relative humidity rose from 35 % to 100 %; additionally, the elongation at break increased to 3.05 %, and the Young's modulus decreased to 4.52 GPa.					
36863669	0	56	theme	humidity-responsive	59:77	arg1	films					111:115	humidity-responsive cellulose nanocrystal composite films	59:115	humidity-responsive cellulose nanocrystal composite films	59:115	Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films.					
36863669	3	57	theme	hydroxyl-rich	575:587	arg1	molecules					595:603	hydroxyl-rich small molecules	575:603	hydroxyl-rich small molecules (glycerol, sorbitol)	575:624	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	1	58	theme	cellulose	154:162	arg1	nanocrystals					164:175	cellulose nanocrystals	154:175	cellulose nanocrystals (CNC)	154:181	Photonic crystal materials based on cellulose nanocrystals (CNC), which are environmentally responsive and green, have attracted widespread attention.					
36863669	1	58	theme	cellulose	154:162	arg1	CNC					178:180	CNC	178:180	CNC	178:180	Photonic crystal materials based on cellulose nanocrystals (CNC), which are environmentally responsive and green, have attracted widespread attention.					
36863669	5	59	theme	optical	1236:1242	arg1	activities					1244:1253	their optical activities	1230:1253	their optical activities	1230:1253	The hydrogen bond network structure provided by trace amounts of the DESs or NADESs not only improved the mechanical properties of the composite films but also increased their water absorption capacities without destroying their optical activities.					
36863669	3	60	theme	polyethylene	659:670	arg1	alcohol					650:656	polyvinyl alcohol	640:656	polyvinyl alcohol	640:656	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	60	theme	polyethylene	659:670	arg1	glycol					672:677	polyethylene glycol	659:677	polyethylene glycol	659:677	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	3	61	theme	small	589:593	arg1	molecules					595:603	hydroxyl-rich small molecules	575:603	hydroxyl-rich small molecules (glycerol, sorbitol)	575:624	In this study, a new green deep eutectic solvents (DESs) and an amino acid-based natural deep eutectic solvents (NADESs) were introduced into CNC suspensions for the first time, and hydroxyl-rich small molecules (glycerol, sorbitol) and polymers (polyvinyl alcohol, polyethylene glycol) were coassembled with the DESs and NADESs to form three-component composite films.					
36863669	1	62	theme	widespread	247:256	arg1	attention					258:266	widespread attention	247:266	widespread attention	247:266	Photonic crystal materials based on cellulose nanocrystals (CNC), which are environmentally responsive and green, have attracted widespread attention.					
36414076	0	0	theme	tissue	118:123	arg1	application					137:147	soft tissue engineering application	113:147	soft tissue engineering application	113:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	4	1	theme	%	817:817	arg1	PLA-CFs					819:825	2 % PLA-CFs	815:825	2 % PLA-CFs	815:825	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	3	2	theme	scaffolds	489:497	arg1	characterization					460:475	Morphological characterization	446:475	Morphological characterization of prepared scaffolds	446:497	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	4	3	contain	had	827:829	arg1	samples					791:797	samples	791:797	samples reinforced with 2 % PLA-CFs	791:825	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	4	3	contain	had	827:829	arg2	properties					851:860	enhanced mechanical properties	831:860	enhanced mechanical properties	831:860	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	0	4	theme	soft	113:116	arg1	application					137:147	soft tissue engineering application	113:147	soft tissue engineering application	113:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	2	5	used	used	440:443	arg2	PLA-CFs					354:360	PLA-CFs	354:360	PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	354:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	5	used	used	440:443	arg2	amounts					343:349	different amounts	333:349	different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	333:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	4	6	theme	2 	815:816	arg1	%					817:817	%	817:817	%	817:817	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	0	7	contain	containing	77:86	arg1	scaffolds					67:75	chitosan/gelatin composite scaffolds	40:75	chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application	40:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	0	7	contain	containing	77:86	arg2	nano/microfibers					92:107	PLA nano/microfibers	88:107	PLA nano/microfibers for soft tissue engineering application	88:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	1	8	theme	chitosan/gelatin	197:212	arg1	scaffolds					224:232	chitosan/gelatin composite scaffolds	197:232	chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	197:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	7	9	theme	studies	1146:1152	arg1	results					1122:1128	The results	1118:1128	The results of cell culture studies	1118:1152	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	8	10	theme	better	1393:1398	arg1	penetration					1405:1415	significantly better cell penetration	1379:1415	significantly better cell penetration	1379:1415	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	2	11	theme	different	333:341	arg1	PLA-CFs					354:360	PLA-CFs	354:360	PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	354:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	11	theme	different	333:341	arg1	amounts					343:349	different amounts	333:349	different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	333:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	0	12	theme	engineering	125:135	arg1	application					137:147	soft tissue engineering application	113:147	soft tissue engineering application	113:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	4	13	from	evaluation	714:723	arg1	terms					741:745	terms	741:745	terms of compression and tensile mode	741:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	4	14	theme	mechanical	703:712	arg1	evaluation					714:723	mechanical evaluation	703:723	mechanical evaluation of scaffolds in terms of compression and tensile mode	703:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	5	15	theme	tensile	875:881	arg1	strength					883:890	its tensile strength	871:890	its tensile strength	871:890	Indeed, its tensile strength increased from 123.8 to 247.2 kPa for dry and 18.9 to 48.6 kPa for wet conditions.					
36414076	7	16	theme	cell	1133:1136	arg1	studies					1146:1152	cell culture studies	1133:1152	cell culture studies	1133:1152	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	8	17	dep	had	1375:1377	arg1	7					1479:1479	7	1479:1479	7	1479:1479	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	8	17	dep	had	1375:1377	arg1	14					1485:1486	14	1485:1486	14	1485:1486	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	4	18	theme	scaffolds	728:736	arg1	evaluation					714:723	mechanical evaluation	703:723	mechanical evaluation of scaffolds in terms of compression and tensile mode	703:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	1	19	theme	composite	214:222	arg1	scaffolds					224:232	chitosan/gelatin composite scaffolds	197:232	chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	197:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	7	20	theme	culture	1138:1144	arg1	studies					1146:1152	cell culture studies	1133:1152	cell culture studies	1133:1152	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	3	21	theme	initial	520:526	arg1	stage					528:532	the initial stage	516:532	the initial stage of adding PLA-CFs	516:550	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	8	22	theme	control	1452:1458	arg1	ones					1460:1463	the control ones	1448:1463	the control ones	1448:1463	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	2	23	theme	chitosan/gelatin	409:424	arg1	solution					426:433	chitosan/gelatin solution	409:433	chitosan/gelatin solution	409:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	3	24	theme	chopped-fibers	667:680	arg1	aggregations					651:662	aggregations	651:662	aggregations of chopped-fibers	651:680	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	2	25	theme	PLA-CFs	354:360	arg1	PLA-CFs					354:360	PLA-CFs	354:360	PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	354:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	25	theme	PLA-CFs	354:360	arg1	amounts					343:349	different amounts	333:349	different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution	333:433	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	0	26	theme	chitosan/gelatin	40:55	arg1	scaffolds					67:75	chitosan/gelatin composite scaffolds	40:75	chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application	40:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	8	27	theme	2 	1363:1364	arg1	%					1365:1365	%	1365:1365	%	1365:1365	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	4	28	from	scaffolds	728:736	arg1	terms					741:745	terms	741:745	terms of compression and tensile mode	741:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	6	29	theme	tensile	992:998	arg1	modulus					1000:1006	the tensile modulus	988:1006	the tensile modulus associated with both conditions	988:1038	Furthermore, the tensile modulus associated with both conditions increased from 2.99 MPa and 44.5 kPa to 6.43 MPa and 158.4 kPa, respectively.					
36414076	7	30	theme	composite	1187:1195	arg1	scaffold					1197:1204	the prepared composite scaffold	1174:1204	the prepared composite scaffold	1174:1204	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	1	31	theme	spun	262:265	arg1	PLA-CFs					315:321	PLA-CFs	315:321	PLA-CFs	315:321	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	1	31	theme	spun	262:265	arg1	nano/microfibers					297:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers	248:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	248:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	8	32	contain	had	1375:1377	arg2	distribution					1421:1432	distribution	1421:1432	distribution	1421:1432	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	8	32	contain	had	1375:1377	arg2	penetration					1405:1415	significantly better cell penetration	1379:1415	significantly better cell penetration	1379:1415	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	8	32	contain	had	1375:1377	arg1	scaffolds					1337:1345	scaffolds	1337:1345	scaffolds reinforced with 2 % PLA-CFs	1337:1373	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	3	33	theme	prepared	480:487	arg1	scaffolds					489:497	prepared scaffolds	480:497	prepared scaffolds	480:497	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	4	34	theme	tensile	766:772	arg1	mode					774:777	tensile mode	766:777	tensile mode	766:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	1	35	theme	polylactic	267:276	arg1	PLA-CFs					315:321	PLA-CFs	315:321	PLA-CFs	315:321	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	1	35	theme	polylactic	267:276	arg1	nano/microfibers					297:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers	248:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	248:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	0	36	theme	composite	57:65	arg1	scaffolds					67:75	chitosan/gelatin composite scaffolds	40:75	chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application	40:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	8	37	theme	cell	1284:1287	arg1	study					1302:1306	The cell infiltration study	1280:1306	The cell infiltration study of the samples	1280:1321	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	5	38	theme	wet	959:961	arg1	conditions					963:972	wet conditions	959:972	wet conditions	959:972	Indeed, its tensile strength increased from 123.8 to 247.2 kPa for dry and 18.9 to 48.6 kPa for wet conditions.					
36414076	1	39	theme	acid	278:281	arg1	PLA-CFs					315:321	PLA-CFs	315:321	PLA-CFs	315:321	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	1	39	theme	acid	278:281	arg1	nano/microfibers					297:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers	248:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	248:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	0	40	theme	PLA	88:90	arg1	nano/microfibers					92:107	PLA nano/microfibers	88:107	PLA nano/microfibers for soft tissue engineering application	88:147	Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application.					
36414076	4	41	theme	mechanical	840:849	arg1	properties					851:860	enhanced mechanical properties	831:860	enhanced mechanical properties	831:860	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	3	42	theme	pores	606:610	arg1	wall					594:597	the wall	590:597	the wall of the pores	590:610	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	3	43	theme	chopped	557:563	arg1	fibers					565:570	the chopped fibers	553:570	the chopped fibers	553:570	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	7	44	theme	cell	1246:1249	arg1	proliferation					1251:1263	cell proliferation	1246:1263	cell proliferation	1246:1263	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	4	45	theme	enhanced	831:838	arg1	properties					851:860	enhanced mechanical properties	831:860	enhanced mechanical properties	831:860	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	4	46	theme	mode	774:777	arg1	terms					741:745	terms	741:745	terms of compression and tensile mode	741:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	1	47	theme	current	157:163	arg1	study					165:169	the current study	153:169	the current study	153:169	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	3	48	theme	fiber	629:633	arg1	load					635:638	the fiber load	625:638	the fiber load	625:638	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	8	49	theme	cell	1400:1403	arg1	penetration					1405:1415	significantly better cell penetration	1379:1415	significantly better cell penetration	1379:1415	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	8	50	theme	%	1365:1365	arg1	PLA-CFs					1367:1373	2 % PLA-CFs	1363:1373	2 % PLA-CFs	1363:1373	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	3	51	theme	Morphological	446:458	arg1	characterization					460:475	Morphological characterization	446:475	Morphological characterization of prepared scaffolds	446:497	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	8	52	theme	samples	1315:1321	arg1	study					1302:1306	The cell infiltration study	1280:1306	The cell infiltration study of the samples	1280:1321	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	2	53	dep	PLA-CFs	354:360	arg1	%					380:380	3 %	378:380	3 %	378:380	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	53	dep	PLA-CFs	354:360	arg1	%					389:389	4 % w/v	387:393	4 % w/v	387:393	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	53	dep	PLA-CFs	354:360	arg1	%					365:365	0 %	363:365	0 %	363:365	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	53	dep	PLA-CFs	354:360	arg1	%					370:370	1 %	368:370	1 %	368:370	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	2	53	dep	PLA-CFs	354:360	arg1	%					375:375	2 %	373:375	2 %	373:375	Herein, different amounts of PLA-CFs (0 %, 1 %, 2 %, 3 %, and 4 % w/v) dispersed in chitosan/gelatin solution were used.					
36414076	1	54	theme	PLA	284:286	arg1	PLA-CFs					315:321	PLA-CFs	315:321	PLA-CFs	315:321	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	1	54	theme	PLA	284:286	arg1	nano/microfibers					297:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers	248:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	248:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	4	55	theme	compression	750:760	arg1	terms					741:745	terms	741:745	terms of compression and tensile mode	741:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	8	56	theme	infiltration	1289:1300	arg1	study					1302:1306	The cell infiltration study	1280:1306	The cell infiltration study of the samples	1280:1321	The cell infiltration study of the samples revealed that scaffolds reinforced with 2 % PLA-CFs had significantly better cell penetration and distribution compared with the control ones on both days (7 and 14).					
36414076	7	57	theme	prepared	1178:1185	arg1	scaffold					1197:1204	the prepared composite scaffold	1174:1204	the prepared composite scaffold	1174:1204	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	4	58	from	terms	741:745	arg1	evaluation					714:723	mechanical evaluation	703:723	mechanical evaluation of scaffolds in terms of compression and tensile mode	703:777	Also, mechanical evaluation of scaffolds in terms of compression and tensile mode showed that samples reinforced with 2 % PLA-CFs had enhanced mechanical properties.					
36414076	7	59	theme	appropriate	1216:1226	arg1	biocompatibility					1228:1243	appropriate biocompatibility	1216:1243	appropriate biocompatibility	1216:1243	The results of cell culture studies also confirmed that the prepared composite scaffold exhibited appropriate biocompatibility, cell proliferation and migration.					
36414076	3	60	located	localized	577:585	arg1	stage					528:532	the initial stage	516:532	the initial stage of adding PLA-CFs	516:550	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	3	60	located	localized	577:585	arg1	wall					594:597	the wall	590:597	the wall of the pores	590:610	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	3	60	located	localized	577:585	arg2	fibers					565:570	the chopped fibers	553:570	the chopped fibers	553:570	Morphological characterization of prepared scaffolds revealed that at the initial stage of adding PLA-CFs, the chopped fibers were localized at the wall of the pores; however, as the fiber load increased, aggregations of chopped-fibers could be seen.					
36414076	1	61	theme	chopped	289:295	arg1	PLA-CFs					315:321	PLA-CFs	315:321	PLA-CFs	315:321	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36414076	1	61	theme	chopped	289:295	arg1	nano/microfibers					297:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers	248:312	centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs)	248:322	In the current study, we successfully prepared chitosan/gelatin composite scaffolds reinforced by centrifugally spun polylactic acid (PLA) chopped nano/microfibers (PLA-CFs).					
36144706	7	0	theme	molecular	1260:1268	arg1	docking					1270:1276	molecular docking and MTT assays	1260:1291	docking	1270:1276	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	8	1	theme	reaction	1582:1589	arg1	°C					1606:1607	reaction temperature 50 °C	1582:1607	reaction temperature 50 °C	1582:1607	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	1	theme	reaction	1582:1589	arg1	conditions					1491:1500	the conditions	1487:1500	the conditions of the initiator concentration 55 mmol/L	1487:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	4	2	theme	mixture	626:632	arg1	esterification					606:619	the esterification	602:619	the esterification of a mixture of BX and AD with folic acid (FA)	602:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	10	3	theme	potential	1830:1838	arg1	applications					1840:1851	potential applications	1830:1851	potential applications	1830:1851	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	2	4	theme	low	307:309	arg1	activity					322:329	The low biological activity	303:329	The low biological activity of andrographolide (AD)	303:353	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	1	5	theme	bagasse	238:244	arg1	xylan					246:250	bagasse xylan	238:250	bagasse xylan (BX)	238:255	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	1	5	theme	bagasse	238:244	arg1	BX					253:254	BX	253:254	BX	253:254	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	1	5	theme	bagasse	238:244	arg1	biomaterial					225:235	a biocompatible biomaterial	209:235	a biocompatible biomaterial	209:235	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	10	6	theme	anticancer	1875:1884	arg1	drug					1886:1889	anticancer drug	1875:1889	anticancer drug	1875:1889	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	9	7	theme	inhibition	1636:1645	arg1	rate					1647:1650	The inhibition rate	1632:1650	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460)	1632:1720	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	6	8	theme	obtained	1189:1196	arg1	product					1198:1204	the obtained product	1185:1204	the obtained product	1185:1204	The structure of the obtained product was characterized by FTIR, SEM, XRD and DTG.					
36144706	4	9	theme	folic	652:656	arg1	acid					658:661	folic acid	652:661	folic acid (FA)	652:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	9	theme	folic	652:656	arg1	FA					664:665	FA	664:665	FA	664:665	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	2	10	theme	andrographolide	334:348	arg1	activity					322:329	The low biological activity	303:329	The low biological activity of andrographolide (AD)	303:353	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	9	11	theme	NPs	1680:1682	arg1	rate					1647:1650	The inhibition rate	1632:1650	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460)	1632:1720	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	8	12	theme	product	1465:1471	arg1	%					1479:1479	79%	1477:1479	79%	1477:1479	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	12	theme	product	1465:1471	arg1	GR					1446:1447	the GR	1442:1447	the GR of the obtained product	1442:1471	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	4	13	theme	nanoprecipitation	968:984	arg1	method					986:991	nanoprecipitation method	968:991	nanoprecipitation method	968:991	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	14	theme	xylan/andrographolide	714:734	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	14	theme	xylan/andrographolide	714:734	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	9	15	theme	human	1687:1691	arg1	cells					1705:1709	human lung cancer cells	1687:1709	human lung cancer cells	1687:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	4	16	theme	methacrylate	764:775	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	16	theme	methacrylate	764:775	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	9	17	theme	cancer	1698:1703	arg1	cells					1705:1709	human lung cancer cells	1687:1709	human lung cancer cells	1687:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	4	18	theme	anticancer	677:686	arg1	nanoderivative					688:701	a novel anticancer nanoderivative	669:701	a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	669:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	0	19	theme	Xylan/Andrographolide	104:124	arg1	Nanoderivative					136:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	4	20	theme	dimethacrylate	804:817	arg1	nanoparticles					828:840	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles	706:840	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	20	theme	dimethacrylate	804:817	arg1	NPs					868:870	FA-BX/AD-g-DMAEMA/DEGDMA NPs	843:870	FA-BX/AD-g-DMAEMA/DEGDMA NPs	843:870	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	9	21	dep	times	1766:1770	arg1	higher					1772:1777	higher	1772:1777	higher	1772:1777	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	5	22	theme	time	1040:1043	arg1	effects					998:1004	The effects	994:1004	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR)	994:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	9	23	from	rate	1647:1650	arg1	cells					1705:1709	human lung cancer cells	1687:1709	human lung cancer cells	1687:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	8	24	theme	concentration	1519:1531	arg1	mmol/L					1536:1541	the initiator concentration 55 mmol/L	1505:1541	the initiator concentration 55 mmol/L	1505:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	0	25	theme	Molecular	163:171	arg1	Docking					173:179	Molecular Docking	163:179	Molecular Docking	163:179	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	7	26	theme	target	1358:1363	arg1	proteins					1365:1372	the target proteins	1354:1372	the target proteins	1354:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	8	27	theme	mmol/L	1536:1541	arg1	m					1557:1557	m	1557:1557	m (mixed monomer) = 1:2	1557:1579	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	27	theme	mmol/L	1536:1541	arg1	conditions					1491:1500	the conditions	1487:1500	the conditions of the initiator concentration 55 mmol/L	1487:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	27	theme	mmol/L	1536:1541	arg1	h					1629:1629	reaction time 5 h	1613:1629	reaction time 5 h	1613:1629	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	27	theme	mmol/L	1536:1541	arg1	m					1544:1544	m	1544:1544	m (FA-BX/AD)	1544:1555	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	27	theme	mmol/L	1536:1541	arg1	°C					1606:1607	reaction temperature 50 °C	1582:1607	reaction temperature 50 °C	1582:1607	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	4	28	theme	DMAEMA	778:783	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	28	theme	DMAEMA	778:783	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	3	29	theme	modification	452:463	arg1	esterification					494:507	esterification	494:507	esterification	494:507	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	3	29	theme	modification	452:463	arg1	methods					465:471	chemical modification methods	443:471	chemical modification methods such as grafting and esterification	443:507	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	3	29	theme	modification	452:463	arg1	grafting					481:488	grafting	481:488	grafting	481:488	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	0	30	theme	Dimethylaminoethyl	0:17	arg1	Dimethacrylate					50:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	5	31	theme	reaction	1009:1016	arg1	temperature					1018:1028	reaction temperature	1009:1028	reaction temperature	1009:1028	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	32	theme	/diethylene	785:795	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	32	theme	/diethylene	785:795	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	0	33	theme	Glycol	43:48	arg1	Dimethacrylate					50:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	3	34	theme	anticancer	561:570	arg1	nanomaterial					572:583	a novel anticancer nanomaterial	553:583	a novel anticancer nanomaterial	553:583	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	7	35	theme	docking	1335:1341	arg1	sites					1343:1347	the possible docking sites	1322:1347	the possible docking sites with the target proteins	1322:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	7	35	theme	docking	1335:1341	arg1	product					1409:1415	the product	1405:1415	the product	1405:1415	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	5	36	theme	ratio	1087:1091	arg1	effects					998:1004	The effects	994:1004	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR)	994:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	3	37	theme	biological	524:533	arg1	activity					535:542	the biological activity	520:542	the biological activity	520:542	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	0	38	theme	Folate-Esterified	78:94	arg1	Nanoderivative					136:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	2	39	with	AD	385:386	arg1	activity					412:419	certain anticancer activity	393:419	certain anticancer activity	393:419	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	5	40	theme	FA-BX/AD	1096:1103	arg1	temperature					1018:1028	reaction temperature	1009:1028	reaction temperature	1009:1028	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	5	40	theme	FA-BX/AD	1096:1103	arg1	time					1040:1043	reaction time	1031:1043	reaction time	1031:1043	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	5	40	theme	FA-BX/AD	1096:1103	arg1	concentration					1060:1072	the initiator concentration	1046:1072	the initiator concentration	1046:1072	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	5	40	theme	FA-BX/AD	1096:1103	arg1	ratio					1087:1091	the mass ratio	1078:1091	the mass ratio of FA-BX/AD to mixed monomers	1078:1121	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	41	theme	nanoparticles	828:840	arg1	nanoderivative					688:701	a novel anticancer nanoderivative	669:701	a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	669:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	1	42	used	used	273:276	arg2	biomaterial					225:235	a biocompatible biomaterial	209:235	a biocompatible biomaterial	209:235	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	1	42	used	used	273:276	arg2	BX					253:254	BX	253:254	BX	253:254	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	1	42	used	used	273:276	arg2	xylan					246:250	bagasse xylan	238:250	bagasse xylan (BX)	238:255	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	5	43	theme	concentration	1060:1072	arg1	effects					998:1004	The effects	994:1004	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR)	994:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	44	theme	FA-BX/AD-g-DMAEMA/DEGDMA	843:866	arg1	nanoparticles					828:840	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles	706:840	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	44	theme	FA-BX/AD-g-DMAEMA/DEGDMA	843:866	arg1	NPs					868:870	FA-BX/AD-g-DMAEMA/DEGDMA NPs	843:870	FA-BX/AD-g-DMAEMA/DEGDMA NPs	843:870	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	2	45	theme	certain	393:399	arg1	activity					412:419	certain anticancer activity	393:419	certain anticancer activity	393:419	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	8	46	theme	reaction	1613:1620	arg1	h					1629:1629	reaction time 5 h	1613:1629	reaction time 5 h	1613:1629	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	46	theme	reaction	1613:1620	arg1	conditions					1491:1500	the conditions	1487:1500	the conditions of the initiator concentration 55 mmol/L	1487:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	7	47	theme	MTT	1282:1284	arg1	assays					1286:1291	molecular docking and MTT assays	1260:1291	assays	1286:1291	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	1	48	theme	biomedical	285:294	arg1	field					296:300	the biomedical field	281:300	the biomedical field	281:300	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	4	49	theme	DEGDMA	915:920	arg1	monomers					922:929	DEGDMA monomers	915:929	DEGDMA monomers	915:929	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	50	theme	esterification	606:619	arg1	basis					593:597	the basis	589:597	the basis of the esterification of a mixture of BX and AD with folic acid (FA)	589:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	8	51	theme	temperature	1591:1601	arg1	°C					1606:1607	reaction temperature 50 °C	1582:1607	reaction temperature 50 °C	1582:1607	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	51	theme	temperature	1591:1601	arg1	conditions					1491:1500	the conditions	1487:1500	the conditions of the initiator concentration 55 mmol/L	1487:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	2	52	theme	biological	311:320	arg1	activity					322:329	The low biological activity	303:329	The low biological activity of andrographolide (AD)	303:353	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	6	53	theme	product	1198:1204	arg1	structure					1172:1180	The structure	1168:1180	The structure of the obtained product	1168:1204	The structure of the obtained product was characterized by FTIR, SEM, XRD and DTG.					
36144706	10	54	contain	have	1825:1828	arg1	material					1812:1819	this material	1807:1819	this material	1807:1819	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	10	54	contain	have	1825:1828	arg2	applications					1840:1851	potential applications	1830:1851	potential applications	1830:1851	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	0	55	theme	Biological	185:194	arg1	Activity					196:203	Biological Activity	185:203	Biological Activity	185:203	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	8	56	theme	obtained	1456:1463	arg1	product					1465:1471	the obtained product	1452:1471	the obtained product	1452:1471	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	5	57	theme	grafting	1130:1137	arg1	GR					1145:1146	GR	1145:1146	GR	1145:1146	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	5	57	theme	grafting	1130:1137	arg1	rate					1139:1142	the grafting rate	1126:1142	the grafting rate (GR)	1126:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	9	58	theme	FA-BX/AD-g-DMAEMA/DEGDMA	1655:1678	arg1	NPs					1680:1682	FA-BX/AD-g-DMAEMA/DEGDMA NPs	1655:1682	FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells	1655:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	7	59	theme	product	1409:1415	arg1	activity					1393:1400	the anticancer activity	1378:1400	the anticancer activity of the product	1378:1415	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	7	59	theme	product	1409:1415	arg1	sites					1343:1347	the possible docking sites	1322:1347	the possible docking sites with the target proteins	1322:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	7	59	theme	product	1409:1415	arg1	product					1409:1415	the product	1405:1415	the product	1405:1415	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	10	60	theme	carriers	1894:1901	arg1	development					1860:1870	the development	1856:1870	the development of anticancer drug or carriers and functional materials	1856:1926	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	7	61	with	sites	1343:1347	arg1	proteins					1365:1372	the target proteins	1354:1372	the target proteins	1354:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	4	62	theme	graft	941:945	arg1	copolymerization					947:962	a graft copolymerization	939:962	a graft copolymerization	939:962	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	63	theme	bagasse	706:712	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	63	theme	bagasse	706:712	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	10	64	theme	drug	1886:1889	arg1	development					1860:1870	the development	1856:1870	the development of anticancer drug or carriers and functional materials	1856:1926	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	5	65	theme	mixed	1108:1112	arg1	monomers					1114:1121	mixed monomers	1108:1121	mixed monomers	1108:1121	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	66	with	mixture	626:632	arg1	acid					658:661	folic acid	652:661	folic acid (FA)	652:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	66	with	mixture	626:632	arg1	FA					664:665	FA	664:665	FA	664:665	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	9	67	theme	lung	1693:1696	arg1	cells					1705:1709	human lung cancer cells	1687:1709	human lung cancer cells	1687:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	7	68	theme	anticancer	1382:1391	arg1	activity					1393:1400	the anticancer activity	1378:1400	the anticancer activity of the product	1378:1415	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	4	69	theme	folate-g-dimethylaminoethyl	736:762	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	69	theme	folate-g-dimethylaminoethyl	736:762	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	0	70	theme	Composite	126:134	arg1	Nanoderivative					136:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	9	71	from	NPs	1680:1682	arg1	cells					1705:1709	human lung cancer cells	1687:1709	human lung cancer cells	1687:1709	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	4	72	theme	novel	671:675	arg1	nanoderivative					688:701	a novel anticancer nanoderivative	669:701	a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	669:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	10	73	theme	functional	1907:1916	arg1	materials					1918:1926	functional materials	1907:1926	functional materials	1907:1926	Therefore, this material may have potential applications in the development of anticancer drug or carriers and functional materials.					
36144706	1	74	theme	biocompatible	211:223	arg1	xylan					246:250	bagasse xylan	238:250	bagasse xylan (BX)	238:255	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	1	74	theme	biocompatible	211:223	arg1	biomaterial					225:235	a biocompatible biomaterial	209:235	a biocompatible biomaterial	209:235	As a biocompatible biomaterial, bagasse xylan (BX) has been widely used in the biomedical field.					
36144706	8	75	theme	initiator	1509:1517	arg1	mmol/L					1536:1541	the initiator concentration 55 mmol/L	1505:1541	the initiator concentration 55 mmol/L	1505:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	7	76	with	activity	1393:1400	arg1	proteins					1365:1372	the target proteins	1354:1372	the target proteins	1354:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	5	77	theme	reaction	1031:1038	arg1	time					1040:1043	reaction time	1031:1043	reaction time	1031:1043	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	78	theme	glycol	797:802	arg1	dimethacrylate					804:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate	706:817	bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs)	706:871	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	4	78	theme	glycol	797:802	arg1	DEGDMA					820:825	DEGDMA	820:825	DEGDMA	820:825	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	0	79	theme	Methacrylate/Diethylene	19:41	arg1	Dimethacrylate					50:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate	0:63	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	5	80	from	effects	998:1004	arg1	GR					1145:1146	GR	1145:1146	GR	1145:1146	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	5	80	from	effects	998:1004	arg1	rate					1139:1142	the grafting rate	1126:1142	the grafting rate (GR)	1126:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	2	81	theme	anticancer	401:410	arg1	activity					412:419	certain anticancer activity	393:419	certain anticancer activity	393:419	The low biological activity of andrographolide (AD) restricts its development, so AD with certain anticancer activity is introduced.					
36144706	5	82	theme	temperature	1018:1028	arg1	effects					998:1004	The effects	994:1004	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR)	994:1147	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	7	83	theme	possible	1326:1333	arg1	sites					1343:1347	the possible docking sites	1322:1347	the possible docking sites with the target proteins	1322:1372	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	7	83	theme	possible	1326:1333	arg1	product					1409:1415	the product	1405:1415	the product	1405:1415	Further, molecular docking and MTT assays were performed to understand the possible docking sites with the target proteins and the anticancer activity of the product.					
36144706	5	84	theme	mass	1082:1085	arg1	ratio					1087:1091	the mass ratio	1078:1091	the mass ratio of FA-BX/AD to mixed monomers	1078:1121	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	3	85	theme	chemical	443:450	arg1	esterification					494:507	esterification	494:507	esterification	494:507	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	3	85	theme	chemical	443:450	arg1	methods					465:471	chemical modification methods	443:471	chemical modification methods such as grafting and esterification	443:507	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	3	85	theme	chemical	443:450	arg1	grafting					481:488	grafting	481:488	grafting	481:488	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
36144706	0	86	theme	Bagasse	96:102	arg1	Nanoderivative					136:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative	78:149	Dimethylaminoethyl Methacrylate/Diethylene Glycol Dimethacrylate Grafted onto Folate-Esterified Bagasse Xylan/Andrographolide Composite Nanoderivative: Synthesis, Molecular Docking and Biological Activity.					
36144706	9	87	theme	7.6	1762:1764	arg1	times					1766:1770	times	1766:1770	times	1766:1770	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	8	88	theme	mixed	1560:1564	arg1	m					1557:1557	m	1557:1557	m (mixed monomer) = 1:2	1557:1579	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	88	theme	mixed	1560:1564	arg1	monomer					1566:1572	mixed monomer	1560:1572	mixed monomer	1560:1572	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	5	89	theme	initiator	1050:1058	arg1	concentration					1060:1072	the initiator concentration	1046:1072	the initiator concentration	1046:1072	The effects of reaction temperature, reaction time, the initiator concentration and the mass ratio of FA-BX/AD to mixed monomers on the grafting rate (GR) were investigated.					
36144706	4	90	theme	BX	637:638	arg1	mixture					626:632	a mixture	624:632	a mixture of BX and AD with folic acid (FA)	624:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	8	91	theme	time	1622:1625	arg1	h					1629:1629	reaction time 5 h	1613:1629	reaction time 5 h	1613:1629	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	8	91	theme	time	1622:1625	arg1	conditions					1491:1500	the conditions	1487:1500	the conditions of the initiator concentration 55 mmol/L	1487:1541	The results showed that the GR of the obtained product was 79% under the conditions of the initiator concentration 55 mmol/L, m (FA-BX/AD):m (mixed monomer) = 1:2, reaction temperature 50 °C and reaction time 5 h.					
36144706	9	92	from	cells	1705:1709	arg1	rate					1647:1650	The inhibition rate	1632:1650	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460)	1632:1720	The inhibition rate of FA-BX/AD-g-DMAEMA/DEGDMA NPs on human lung cancer cells (NCI-H460) can reach 39.77 ± 5.62%, which is about 7.6 times higher than that of BX.					
36144706	4	93	theme	AD	644:645	arg1	mixture					626:632	a mixture	624:632	a mixture of BX and AD with folic acid (FA)	624:666	On the basis of the esterification of a mixture of BX and AD with folic acid (FA), a novel anticancer nanoderivative of bagasse xylan/andrographolide folate-g-dimethylaminoethyl methacrylate (DMAEMA)/diethylene glycol dimethacrylate (DEGDMA) nanoparticles (FA-BX/AD-g-DMAEMA/DEGDMA NPs) was synthesized by introducing DMAEMA and DEGDMA monomers through a graft copolymerization and nanoprecipitation method.					
36144706	3	94	theme	novel	555:559	arg1	nanomaterial					572:583	a novel anticancer nanomaterial	553:583	a novel anticancer nanomaterial	553:583	We use chemical modification methods such as grafting and esterification to improve the biological activity and make a novel anticancer nanomaterial.					
35285168	2	0	theme	magnitude	459:467	arg1	orders					449:454	orders	449:454	orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers	449:573	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	4	1	theme	%	735:735	arg1	efficiency					716:725	an energy conversion efficiency	695:725	an energy conversion efficiency	695:725	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	1	2	theme	humidity	164:171	arg1	changes					173:179	humidity changes	164:179	humidity changes	164:179	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	2	3	theme	used	501:504	arg1	actuators					539:547	piezoelectric actuators	525:547	piezoelectric actuators	525:547	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	3	theme	used	501:504	arg1	actuators					506:514	frequently used actuators	490:514	frequently used actuators	490:514	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	3	theme	used	501:504	arg1	elastomers					564:573	dielectric elastomers	553:573	dielectric elastomers	553:573	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	4	4	theme	water	846:850	arg1	molecules					852:860	water molecules	846:860	water molecules	846:860	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	1	5	dep	changes	173:179	arg1	response					152:159	response	152:159	response	152:159	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	4	6	theme	conversion	705:714	arg1	efficiency					716:725	an energy conversion efficiency	695:725	an energy conversion efficiency	695:725	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	4	7	theme	energy	698:703	arg1	efficiency					716:725	an energy conversion efficiency	695:725	an energy conversion efficiency	695:725	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	2	8	theme	power	381:385	arg1	densities					387:395	power densities	381:395	power densities	381:395	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	0	9	theme	High	0:3	arg1	Energy					5:10	High Energy	0:10	High Energy	0:10	High Energy and Power Density Peptidoglycan Muscles through Super-Viscous Nanoconfined Water.					
35285168	1	10	theme	Water-responsive	94:109	arg1	materials					116:124	Water-responsive (WR) materials	94:124	Water-responsive (WR) materials that reversibly deform in response to humidity changes	94:179	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	1	10	theme	Water-responsive	94:109	arg1	WR					112:113	WR	112:113	WR	112:113	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	1	11	theme	great	186:190	arg1	potential					192:200	great potential	186:200	great potential for developing muscle-like actuators for miniature and biomimetic robotics	186:275	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	2	12	theme	MW	426:427	arg1	m-3					429:431	9.1 MW m-3	422:431	9.1 MW m-3	422:431	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	5	13	theme	high-efficiency	1115:1129	arg1	actuators					1134:1142	high-efficiency WR actuators	1115:1142	high-efficiency WR actuators	1115:1142	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	2	14	theme	actuation	360:368	arg1	energy					370:375	WR actuation energy	357:375	WR actuation energy	357:375	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	0	15	theme	Power	16:20	arg1	Density					22:28	Power Density	16:28	Power Density	16:28	High Energy and Power Density Peptidoglycan Muscles through Super-Viscous Nanoconfined Water.					
35285168	5	16	theme	WR	1131:1132	arg1	actuators					1134:1142	high-efficiency WR actuators	1115:1142	high-efficiency WR actuators	1115:1142	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	4	17	theme	nanoconfined	783:794	arg1	water					796:800	its super-viscous nanoconfined water	765:800	its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation	765:891	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	4	18	theme	mechanical	870:879	arg1	deformation					881:891	PG's mechanical deformation	865:891	PG's mechanical deformation	865:891	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	2	19	theme	Bacillus	305:312	arg1	peptidoglycan					329:341	Bacillus (B.) subtilis' peptidoglycan	305:341	Bacillus (B.) subtilis' peptidoglycan (PG)	305:346	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	19	theme	Bacillus	305:312	arg1	PG					344:345	PG	344:345	PG	344:345	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	20	theme	72.6 MJ	406:412	arg1	m-3					414:416	72.6 MJ m-3	406:416	72.6 MJ m-3	406:416	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	5	21	theme	engineering	957:967	arg1	structures					969:978	engineering structures	957:978	engineering structures	957:978	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	1	22	theme	muscle-like	217:227	arg1	actuators					229:237	muscle-like actuators	217:237	muscle-like actuators for miniature and biomimetic robotics	217:275	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	5	23	theme	linear	1027:1032	arg1	actuators					1034:1042	linear actuators	1027:1042	linear actuators	1027:1042	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	5	24	theme	structures	969:978	arg1	range					948:952	a range	946:952	a range of engineering structures	946:978	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	5	25	theme	building	1095:1102	arg1	blocks					1104:1109	building blocks	1095:1109	building blocks for high-efficiency WR actuators	1095:1142	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	5	25	theme	building	1095:1102	arg1	PG					1089:1090	PG	1089:1090	PG	1089:1090	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	2	26	theme	dielectric	553:562	arg1	elastomers					564:573	dielectric elastomers	553:573	dielectric elastomers	553:573	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	27	theme	higher	469:474	arg1	orders					449:454	orders	449:454	orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers	449:573	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	0	28	dep	Peptidoglycan	30:42	arg1	Muscles					44:50	Muscles	44:50	Muscles	44:50	High Energy and Power Density Peptidoglycan Muscles through Super-Viscous Nanoconfined Water.					
35285168	4	29	theme	molecules	852:860	arg1	movement					834:841	the movement	830:841	the movement of water molecules to PG's mechanical deformation	830:891	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	4	30	theme	super-viscous	769:781	arg1	water					796:800	its super-viscous nanoconfined water	765:800	its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation	765:891	Surprisingly, PG exhibits an energy conversion efficiency of ≈66.8%, which can be attributed to its super-viscous nanoconfined water that efficiently translates the movement of water molecules to PG's mechanical deformation.					
35285168	3	31	theme	actuation	630:638	arg1	pressure					640:647	its actuation pressure	626:647	its actuation pressure	626:647	PG can deform as much as 27.2% within 110 ms, and its actuation pressure reaches ≈354.6 MPa.					
35285168	5	32	theme	WR	904:905	arg1	composites					907:916	WR composites	904:916	WR composites that can be integrated into a range of engineering structures	904:978	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	2	33	theme	piezoelectric	525:537	arg1	actuators					539:547	piezoelectric actuators	525:547	piezoelectric actuators	525:547	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	34	theme	subtilis	319:326	arg1	peptidoglycan					329:341	Bacillus (B.) subtilis' peptidoglycan	305:341	Bacillus (B.) subtilis' peptidoglycan (PG)	305:346	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	2	34	theme	subtilis	319:326	arg1	PG					344:345	PG	344:345	PG	344:345	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	1	35	theme	miniature	243:251	arg1	robotics					268:275	miniature and biomimetic robotics	243:275	miniature and biomimetic robotics	243:275	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
35285168	0	36	theme	Nanoconfined	74:85	arg1	Water					87:91	Super-Viscous Nanoconfined Water	60:91	Super-Viscous Nanoconfined Water	60:91	High Energy and Power Density Peptidoglycan Muscles through Super-Viscous Nanoconfined Water.					
35285168	5	37	theme	robotic	1007:1013	arg1	gripper					1015:1021	a robotic gripper	1005:1021	a robotic gripper	1005:1021	Using PG, WR composites that can be integrated into a range of engineering structures are developed, including a robotic gripper and linear actuators, which illustrate the possibilities of using PG as building blocks for high-efficiency WR actuators.					
35285168	2	38	theme	WR	357:358	arg1	energy					370:375	WR actuation energy	357:375	WR actuation energy	357:375	Here, it is presented that Bacillus (B.) subtilis' peptidoglycan (PG) exhibits WR actuation energy and power densities reaching 72.6 MJ m-3 and 9.1 MW m-3 , respectively, orders of magnitude higher than those of frequently used actuators, such as piezoelectric actuators and dielectric elastomers.					
35285168	0	39	theme	Super-Viscous	60:72	arg1	Water					87:91	Super-Viscous Nanoconfined Water	60:91	Super-Viscous Nanoconfined Water	60:91	High Energy and Power Density Peptidoglycan Muscles through Super-Viscous Nanoconfined Water.					
35285168	1	40	theme	biomimetic	257:266	arg1	robotics					268:275	miniature and biomimetic robotics	243:275	miniature and biomimetic robotics	243:275	Water-responsive (WR) materials that reversibly deform in response to humidity changes show great potential for developing muscle-like actuators for miniature and biomimetic robotics.					
36502944	0	0	theme	algae	93:97	arg1	species					99:105	different European Brown algae species	68:105	different European Brown algae species	68:105	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	6	1	theme	highest	795:801	arg1	acid					834:837	mannuronic acid/guluronic acid	808:837	mannuronic acid/guluronic acid	808:837	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	1	theme	highest	795:801	arg1	M/G					803:805	the highest M/G	791:805	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	1	2	theme	sustainable	158:168	arg1	alternatives					170:181	sustainable alternatives	158:181	sustainable alternatives	158:181	Applications of natural fibres are expanding, and sustainable alternatives are needed to support this growing demand.					
36502944	0	3	theme	Brown	87:91	arg1	species					99:105	different European Brown algae species	68:105	different European Brown algae species	68:105	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	7	4	theme	spinning	1036:1043	arg1	fibres					1045:1050	spinning fibres	1036:1050	spinning fibres cross-linked with CaCl2	1036:1074	When the four types of alginates were tested for spinning fibres cross-linked with CaCl2, only SAC and LAM alginates produced fibres.					
36502944	6	5	dep	compared	874:881	arg1	M/G:1.98					911:918	M/G:1.98	911:918	M/G:1.98	911:918	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	5	dep	compared	874:881	arg1	MW					930:931	MW	930:931	MW	930:931	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	5	dep	compared	874:881	arg1	2.23					924:927	2.23	924:927	2.23	924:927	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	2	6	from	digitata	326:333	arg1	alginates					273:281	alginates	273:281	alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp	273:391	We investigated the production of fibres using alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp.					
36502944	4	7	theme	material	660:667	arg1	1.5 g					642:646	1.5 g	642:646	1.5 g of starting material	642:667	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	8	theme	biomass	529:535	arg1	weight					541:546	the biomass dry weight	525:546	the biomass dry weight for SAC and LAM	525:562	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	7	9	theme	alginates	1010:1018	arg1	types					1001:1005	the four types	992:1005	the four types of alginates	992:1018	When the four types of alginates were tested for spinning fibres cross-linked with CaCl2, only SAC and LAM alginates produced fibres.					
36502944	4	10	theme	starting	651:658	arg1	material					660:667	starting material	651:667	starting material	651:667	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	11	theme	 w/v	422:425	arg1	biomass					427:433	3 % w/v biomass	419:433	3 % w/v biomass	419:433	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	11	theme	 w/v	422:425	arg1	extraction					407:416	extraction	407:416	extraction (3 % w/v biomass) using a sustainable protocol based on citric acid	407:484	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	6	12	contain	had	787:789	arg2	weights					861:867	molecular weights	851:867	molecular weights	851:867	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	12	contain	had	787:789	arg2	ratios					840:845	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	12	contain	had	787:789	arg1	alginates					777:785	SAC and LAM alginates	765:785	SAC and LAM alginates	765:785	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	5	13	dep	extraction	697:706	arg1	60 g					709:712	60 g	709:712	60 g of starting material	709:733	Interestingly, scaling-up extraction (60 g of starting material) decreased yields to 26-30 %.					
36502944	6	14	dep	M/G:1.98	911:918	arg1	362 kDa					942:948	362 kDa	942:948	362 kDa	942:948	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	14	dep	M/G:1.98	911:918	arg1	1.83					954:957	1.83	954:957	1.83	954:957	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	14	dep	M/G:1.98	911:918	arg1	302					934:936	302	934:936	302	934:936	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	14	dep	M/G:1.98	911:918	arg1	168 kDa					977:983	168 kDa	977:983	168 kDa	977:983	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	14	dep	M/G:1.98	911:918	arg1	268					969:971	268	969:971	268	969:971	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	0	15	theme	benign	16:21	arg1	extraction					32:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	6	16	theme	SAC	765:767	arg1	alginates					777:785	SAC and LAM alginates	765:785	SAC and LAM alginates	765:785	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	8	17	theme	stretching	1167:1176	arg1	action					1178:1183	stretching action	1167:1183	stretching action	1167:1183	These fibres showed no clumps or cracks under stretching action and presented a similar Young's modulus (2.4 and 2.0 GPa).					
36502944	6	18	theme	LAM	773:775	arg1	alginates					777:785	SAC and LAM alginates	765:785	SAC and LAM alginates	765:785	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	0	19	theme	Environmentally	0:14	arg1	extraction					32:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	6	20	theme	molecular	851:859	arg1	weights					861:867	molecular weights	851:867	molecular weights	851:867	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	9	21	theme	functional	1353:1362	arg1	fibres					1364:1369	functional fibres	1353:1369	functional fibres cross-linked with CaCl2	1353:1393	We have demonstrated that alginate extracted from S. latissima and L. digitata can be successfully spun into functional fibres cross-linked with CaCl2.					
36502944	4	22	theme	crude	487:491	arg1	alginate					493:500	crude alginate	487:500	crude alginate	487:500	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	2	23	from	polyschides	353:363	arg1	alginates					273:281	alginates	273:281	alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp	273:391	We investigated the production of fibres using alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp.					
36502944	5	24	theme	material	726:733	arg1	60 g					709:712	60 g	709:712	60 g of starting material	709:733	Interestingly, scaling-up extraction (60 g of starting material) decreased yields to 26-30 %.					
36502944	0	25	theme	alginate	23:30	arg1	extraction					32:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction	0:41	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	1	26	theme	growing	210:216	arg1	demand					218:223	this growing demand	205:223	this growing demand	205:223	Applications of natural fibres are expanding, and sustainable alternatives are needed to support this growing demand.					
36502944	7	27	theme	LAM	1090:1092	arg1	alginates					1094:1102	only SAC and LAM alginates	1077:1102	only SAC and LAM alginates	1077:1102	When the four types of alginates were tested for spinning fibres cross-linked with CaCl2, only SAC and LAM alginates produced fibres.					
36502944	4	28	theme	citric	474:479	arg1	acid					481:484	citric acid	474:484	citric acid	474:484	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	29	theme	%	421:421	arg1	biomass					427:433	3 % w/v biomass	419:433	3 % w/v biomass	419:433	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	29	theme	%	421:421	arg1	extraction					407:416	extraction	407:416	extraction (3 % w/v biomass) using a sustainable protocol based on citric acid	407:484	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	8	30	dep	modulus	1217:1223	arg1	2.0 GPa					1234:1240	2.0 GPa	1234:1240	2.0 GPa	1234:1240	These fibres showed no clumps or cracks under stretching action and presented a similar Young's modulus (2.4 and 2.0 GPa).					
36502944	8	30	dep	modulus	1217:1223	arg1	2.4					1226:1228	2.4	1226:1228	2.4	1226:1228	These fibres showed no clumps or cracks under stretching action and presented a similar Young's modulus (2.4 and 2.0 GPa).					
36502944	5	31	theme	scaling-up	686:695	arg1	extraction					697:706	scaling-up extraction	686:706	scaling-up extraction (60 g of starting material)	686:734	Interestingly, scaling-up extraction (60 g of starting material) decreased yields to 26-30 %.					
36502944	6	32	theme	acid/guluronic	819:832	arg1	acid					834:837	mannuronic acid/guluronic acid	808:837	mannuronic acid/guluronic acid	808:837	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	32	theme	acid/guluronic	819:832	arg1	M/G					803:805	the highest M/G	791:805	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	4	33	theme	3 	419:420	arg1	biomass					427:433	3 % w/v biomass	419:433	3 % w/v biomass	419:433	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	33	theme	3 	419:420	arg1	extraction					407:416	extraction	407:416	extraction (3 % w/v biomass) using a sustainable protocol based on citric acid	407:484	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	8	34	theme	Young	1209:1213	arg1	modulus					1217:1223	Young's modulus	1209:1223	a similar Young's modulus (2.4 and 2.0 GPa)	1199:1241	These fibres showed no clumps or cracks under stretching action and presented a similar Young's modulus (2.4 and 2.0 GPa).					
36502944	1	35	theme	natural	124:130	arg1	fibres					132:137	natural fibres	124:137	natural fibres	124:137	Applications of natural fibres are expanding, and sustainable alternatives are needed to support this growing demand.					
36502944	6	36	theme	mannuronic	808:817	arg1	acid					834:837	mannuronic acid/guluronic acid	808:837	mannuronic acid/guluronic acid	808:837	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	36	theme	mannuronic	808:817	arg1	M/G					803:805	the highest M/G	791:805	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	6	37	theme	M/G	803:805	arg1	ratios					840:845	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	the highest M/G (mannuronic acid/guluronic acid) ratios	791:845	SAC and LAM alginates had the highest M/G (mannuronic acid/guluronic acid) ratios and molecular weights when compared to those from SACC and HIM (M/G:1.98 and 2.23, MW: 302 and 362 kDa, vs 1.83 and 1.86, 268 and 168 kDa).					
36502944	8	38	theme	similar	1201:1207	arg1	modulus					1217:1223	Young's modulus	1209:1223	a similar Young's modulus (2.4 and 2.0 GPa)	1199:1241	These fibres showed no clumps or cracks under stretching action and presented a similar Young's modulus (2.4 and 2.0 GPa).					
36502944	7	39	theme	SAC	1082:1084	arg1	alginates					1094:1102	only SAC and LAM alginates	1077:1102	only SAC and LAM alginates	1077:1102	When the four types of alginates were tested for spinning fibres cross-linked with CaCl2, only SAC and LAM alginates produced fibres.					
36502944	1	40	theme	fibres	132:137	arg1	Applications					108:119	Applications	108:119	Applications of natural fibres	108:137	Applications of natural fibres are expanding, and sustainable alternatives are needed to support this growing demand.					
36502944	4	41	theme	small	629:633	arg1	scale					635:639	small scale	629:639	small scale (1.5 g of starting material)	629:668	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	42	theme	weight	541:546	arg1	%					575:575	34-41 %	569:575	34-41 % for SACC and HIM	569:592	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	42	theme	weight	541:546	arg1	%					520:520	61-65 %	514:520	61-65 % of the biomass dry weight for SAC and LAM	514:562	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	42	theme	weight	541:546	arg1	weight					541:546	the biomass dry weight	525:546	the biomass dry weight for SAC and LAM	525:562	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	2	43	from	spp	389:391	arg1	alginates					273:281	alginates	273:281	alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp	273:391	We investigated the production of fibres using alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp.					
36502944	4	44	dep	scale	635:639	arg1	1.5 g					642:646	1.5 g	642:646	1.5 g of starting material	642:667	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	4	45	theme	dry	537:539	arg1	weight					541:546	the biomass dry weight	525:546	the biomass dry weight for SAC and LAM	525:562	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	0	46	theme	European	78:85	arg1	species					99:105	different European Brown algae species	68:105	different European Brown algae species	68:105	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	2	47	theme	fibres	260:265	arg1	production					246:255	the production	242:255	the production of fibres	242:265	We investigated the production of fibres using alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp.					
36502944	2	48	from	latissima	299:307	arg1	alginates					273:281	alginates	273:281	alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp	273:391	We investigated the production of fibres using alginates from Saccharina latissima (SAC), Laminaria digitata (LAM), Sacchoriza polyschides (SACC), and Himanthalia spp.					
36502944	0	49	theme	different	68:76	arg1	species					99:105	different European Brown algae species	68:105	different European Brown algae species	68:105	Environmentally benign alginate extraction and fibres spinning from different European Brown algae species.					
36502944	4	50	theme	sustainable	444:454	arg1	protocol					456:463	a sustainable protocol	442:463	a sustainable protocol based on citric acid	442:484	After extraction (3 % w/v biomass) using a sustainable protocol based on citric acid, crude alginate represented 61-65 % of the biomass dry weight for SAC and LAM, and 34-41 % for SACC and HIM when experiments were performed at small scale (1.5 g of starting material).					
36502944	5	51	theme	starting	717:724	arg1	material					726:733	starting material	717:733	starting material	717:733	Interestingly, scaling-up extraction (60 g of starting material) decreased yields to 26-30 %.					
35594940	8	0	contain	had	1009:1011	arg1	addition					965:972	The addition	961:972	The addition of fibers in the surface structure	961:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	8	0	contain	had	1009:1011	arg2	impact					1027:1032	a significant impact	1013:1032	a significant impact	1013:1032	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	11	1	theme	environmentally	1543:1557	arg1	applications					1583:1594	environmentally friendly food packaging applications	1543:1594	environmentally friendly food packaging applications	1543:1594	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	1	2	theme	starch	279:284	arg1	films					293:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films	211:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	2	3	theme	TPAS/AF-10	555:564	arg1	film					579:582	The TPAS/AF-10 biocomposite film	551:582	The TPAS/AF-10 biocomposite film	551:582	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	11	4	theme	biocomposites	1525:1537	arg1	properties					1511:1520	the properties	1507:1520	the properties of biocomposites for environmentally friendly food packaging applications	1507:1594	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	3	5	from	reduction	779:787	arg1	rate					811:814	linear burning rate	796:814	linear burning rate	796:814	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	3	5	from	reduction	779:787	arg1	WVP					820:822	WVP	820:822	WVP	820:822	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	2	6	theme	better	680:685	arg1	stability					695:703	better thermal stability	680:703	better thermal stability	680:703	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	1	7	theme	casting	195:201	arg1	method					203:208	the solution casting method	182:208	the solution casting method	182:208	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	8	8	from	addition	965:972	arg1	structure					999:1007	the surface structure	987:1007	the surface structure	987:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	0	9	theme	starch	114:119	arg1	composites					132:141	arrowroot starch biopolymer composites	104:141	arrowroot starch biopolymer composites for food packaging applications	104:173	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	1	10	contain	containing	299:308	arg2	AF					327:328	AF	327:328	AF	327:328	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	10	contain	containing	299:308	arg1	films					293:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films	211:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	10	contain	containing	299:308	arg2	fiber					320:324	arrowroot fiber	310:324	arrowroot fiber (AF)	310:329	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	9	11	theme	film	1130:1133	arg1	incorporation					1098:1110	the incorporation	1094:1110	the incorporation of AF and control film	1094:1133	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	1	12	theme	novel	213:217	arg1	arrowroot					247:255	a novel biodegradable thermoplastic arrowroot	211:255	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	12	theme	novel	213:217	arg1	arundinacea					266:276	Maranta arundinacea	258:276	Maranta arundinacea	258:276	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	5	13	dep	Pa-1	907:910	arg1	s-1					932:934	5.20 × 10-10 ×g. s-1	915:934	5.20 × 10-10 ×g. s-1	915:934	Pa-1 to 5.20 × 10-10 ×g. s-1.					
35594940	0	14	theme	food	147:150	arg1	applications					162:173	food packaging applications	147:173	food packaging applications	147:173	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	3	15	dep	significant	756:766	arg1	p < 0.05					769:776	p < 0.05	769:776	p < 0.05	769:776	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	8	16	from	fibers	977:982	arg1	structure					999:1007	the surface structure	987:1007	the surface structure	987:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	1	17	theme	transmittance	525:537	arg1	properties					539:548	light transmittance properties	519:548	light transmittance properties	519:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	0	18	theme	arrowroot	55:63	arg1	fiber					87:91	arrowroot (Maranta arundinacea) fiber	55:91	arrowroot (Maranta arundinacea) fiber	55:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	8	19	from	structure	999:1007	arg1	addition					965:972	The addition	961:972	The addition of fibers in the surface structure	961:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	10	20	theme	soil	1311:1314	arg1	findings					1323:1330	The soil burial findings	1307:1330	The soil burial findings	1307:1330	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	2	21	theme	biocomposite	649:660	arg1	films					662:666	other biocomposite films	643:666	other biocomposite films	643:666	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	0	22	theme	Maranta	66:72	arg1	fiber					87:91	arrowroot (Maranta arundinacea) fiber	55:91	arrowroot (Maranta arundinacea) fiber	55:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	3	23	theme	burning	803:809	arg1	rate					811:814	linear burning rate	796:814	linear burning rate	796:814	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	8	24	dep	74.1	1073:1076	arg1	to					1070:1071	to	1070:1071	to	1070:1071	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	3	25	theme	significant	756:766	arg1	reduction					779:787	a significant (p < 0.05) reduction	754:787	a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1	754:900	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	3	26	theme	biocomposite	831:842	arg1	films					844:848	the biocomposite films	827:848	the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1	827:900	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	2	27	theme	biocomposite	566:577	arg1	film					579:582	The TPAS/AF-10 biocomposite film	551:582	The TPAS/AF-10 biocomposite film	551:582	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	1	28	theme	vapor	471:475	arg1	permeability					477:488	water vapor permeability	465:488	water vapor permeability (WVP)	465:494	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	28	theme	vapor	471:475	arg1	WVP					491:493	WVP	491:493	WVP	491:493	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	8	29	theme	fibers	977:982	arg1	addition					965:972	The addition	961:972	The addition of fibers in the surface structure	961:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	0	30	theme	Thermal	0:6	arg1	properties					41:50	Thermal, flammability, and antimicrobial properties	0:50	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber	0:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	2	31	theme	higher	595:600	arg1	313.02 °C					627:635	313.02 °C	627:635	313.02 °C	627:635	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	2	31	theme	higher	595:600	arg1	temperature					614:624	a higher degradation temperature	593:624	a higher degradation temperature (313.02 °C) than other biocomposite films	593:666	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	0	32	theme	flammability	9:20	arg1	properties					41:50	Thermal, flammability, and antimicrobial properties	0:50	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber	0:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	10	33	theme	weight	1354:1359	arg1	loss					1361:1364	the weight loss	1350:1364	the weight loss of TPAS/AF biocomposite films	1350:1394	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	10	33	theme	weight	1354:1359	arg1	higher					1414:1419	higher	1414:1419	higher	1414:1419	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	1	34	theme	biodegradability	497:512	arg1	terms					423:427	terms	423:427	terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties	423:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	11	35	theme	packaging	1573:1581	arg1	applications					1583:1594	environmentally friendly food packaging applications	1543:1594	environmentally friendly food packaging applications	1543:1594	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	11	36	theme	arrowroot	1467:1475	arg1	fiber					1477:1481	arrowroot fiber	1467:1481	arrowroot fiber	1467:1481	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	10	37	theme	biocomposite	1377:1388	arg1	films					1390:1394	TPAS/AF biocomposite films	1369:1394	TPAS/AF biocomposite films	1369:1394	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	1	38	theme	thermal	432:438	arg1	activity					455:462	thermal, antibacterial activity	432:462	activity	455:462	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	39	theme	biodegradable	219:231	arg1	arrowroot					247:255	a novel biodegradable thermoplastic arrowroot	211:255	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	39	theme	biodegradable	219:231	arg1	arundinacea					266:276	Maranta arundinacea	258:276	Maranta arundinacea	258:276	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	8	40	theme	remarkable	1037:1046	arg1	drop					1048:1051	remarkable drop	1037:1051	remarkable drop in opacity (91.1 to 74.1%)	1037:1078	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	10	41	theme	TPAS	1426:1429	arg1	film					1431:1434	TPAS film	1426:1434	TPAS film	1426:1434	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	1	42	theme	antibacterial	441:453	arg1	activity					455:462	thermal, antibacterial activity	432:462	activity	455:462	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	43	theme	arrowroot	247:255	arg1	films					293:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films	211:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	44	theme	Maranta	258:264	arg1	arrowroot					247:255	a novel biodegradable thermoplastic arrowroot	211:255	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	44	theme	Maranta	258:264	arg1	arundinacea					266:276	Maranta arundinacea	258:276	Maranta arundinacea	258:276	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	11	45	with	reinforcement	1450:1462	arg1	film					1493:1496	TPAS film	1488:1496	TPAS film	1488:1496	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	1	46	theme	10 wt	379:383	arg1	%					384:384	10 wt%	379:384	10 wt%	379:384	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	3	47	from	rate	811:814	arg1	248.9					855:859	248.9	855:859	248.9	855:859	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	11	48	theme	friendly	1559:1566	arg1	applications					1583:1594	environmentally friendly food packaging applications	1543:1594	environmentally friendly food packaging applications	1543:1594	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	3	49	from	WVP	820:822	arg1	248.9					855:859	248.9	855:859	248.9	855:859	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	2	50	theme	thermal	687:693	arg1	stability					695:703	better thermal stability	680:703	better thermal stability	680:703	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	1	51	theme	solution	186:193	arg1	method					203:208	the solution casting method	182:208	the solution casting method	182:208	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	0	52	theme	biopolymer	121:130	arg1	composites					132:141	arrowroot starch biopolymer composites	104:141	arrowroot starch biopolymer composites for food packaging applications	104:173	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	9	53	theme	AF	1115:1116	arg1	incorporation					1098:1110	the incorporation	1094:1110	the incorporation of AF and control film	1094:1133	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	9	54	theme	control	1122:1128	arg1	film					1130:1133	control film	1122:1133	control film	1122:1133	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	3	55	from	248.9	855:859	arg1	rate					811:814	linear burning rate	796:814	linear burning rate	796:814	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	3	55	from	248.9	855:859	arg1	films					844:848	the biocomposite films	827:848	the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1	827:900	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	3	55	from	248.9	855:859	arg1	WVP					820:822	WVP	820:822	WVP	820:822	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	2	56	theme	other	643:647	arg1	films					662:666	other biocomposite films	643:666	other biocomposite films	643:666	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	3	57	theme	AF	730:731	arg1	concentration					733:745	AF concentration	730:745	AF concentration	730:745	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	0	58	theme	packaging	152:160	arg1	applications					162:173	food packaging applications	147:173	food packaging applications	147:173	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	9	59	theme	insignificant	1145:1157	arg1	effect					1159:1164	an insignificant effect	1142:1164	an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29)	1142:1304	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	3	60	theme	linear	796:801	arg1	rate					811:814	linear burning rate	796:814	linear burning rate	796:814	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	1	61	theme	light	519:523	arg1	properties					539:548	light transmittance properties	519:548	light transmittance properties	519:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	62	theme	properties	539:548	arg1	terms					423:427	terms	423:427	terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties	423:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	0	63	theme	arundinacea	74:84	arg1	fiber					87:91	arrowroot (Maranta arundinacea) fiber	55:91	arrowroot (Maranta arundinacea) fiber	55:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	9	64	theme	pathogenic	1180:1189	arg1	bacteria					1191:1198	three pathogenic bacteria	1174:1198	three pathogenic bacteria	1174:1198	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	9	64	theme	pathogenic	1180:1189	arg1	subtilis					1291:1298	Bacillus subtilis	1282:1298	Bacillus subtilis (B29)	1282:1304	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	9	64	theme	pathogenic	1180:1189	arg1	aureus					1226:1231	Staphylococcus aureus	1211:1231	Staphylococcus aureus (ATCC 43300)	1211:1244	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	9	64	theme	pathogenic	1180:1189	arg1	coli					1259:1262	Escherichia coli	1247:1262	Escherichia coli (ATCC 25922)	1247:1275	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	8	65	from	drop	1048:1051	arg1	%					1077:1077	91.1 to 74.1%	1065:1077	91.1 to 74.1%	1065:1077	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	8	65	from	drop	1048:1051	arg1	opacity					1056:1062	opacity	1056:1062	opacity (91.1 to 74.1%)	1056:1078	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	0	66	theme	fiber	87:91	arg1	properties					41:50	Thermal, flammability, and antimicrobial properties	0:50	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber	0:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	1	67	theme	different	334:342	arg1	concentrations					344:357	different concentrations	334:357	different concentrations (0, 2, 4, 6, 8, and 10 wt%)	334:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	68	theme	water	465:469	arg1	permeability					477:488	water vapor permeability	465:488	water vapor permeability (WVP)	465:494	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	68	theme	water	465:469	arg1	WVP					491:493	WVP	491:493	WVP	491:493	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	0	69	theme	arrowroot	104:112	arg1	composites					132:141	arrowroot starch biopolymer composites	104:141	arrowroot starch biopolymer composites for food packaging applications	104:173	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	3	70	theme	films	844:848	arg1	rate					811:814	linear burning rate	796:814	linear burning rate	796:814	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	3	70	theme	films	844:848	arg1	WVP					820:822	WVP	820:822	WVP	820:822	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	1	71	theme	permeability	477:488	arg1	terms					423:427	terms	423:427	terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties	423:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	8	72	theme	surface	991:997	arg1	structure					999:1007	the surface structure	987:1007	the surface structure	987:1007	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	3	73	dep	rate	811:814	arg1	the					792:794	the	792:794	the	792:794	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	10	74	theme	burial	1316:1321	arg1	findings					1323:1330	The soil burial findings	1307:1330	The soil burial findings	1307:1330	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	2	75	theme	degradation	602:612	arg1	313.02 °C					627:635	313.02 °C	627:635	313.02 °C	627:635	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	2	75	theme	degradation	602:612	arg1	temperature					614:624	a higher degradation temperature	593:624	a higher degradation temperature (313.02 °C) than other biocomposite films	593:666	The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating better thermal stability.					
35594940	1	76	theme	TPAS	287:290	arg1	films					293:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films	211:297	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	0	77	theme	antimicrobial	27:39	arg1	properties					41:50	Thermal, flammability, and antimicrobial properties	0:50	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber	0:91	Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications.					
35594940	8	78	theme	significant	1015:1025	arg1	impact					1027:1032	a significant impact	1013:1032	a significant impact	1013:1032	The addition of fibers in the surface structure had a significant impact on remarkable drop in opacity (91.1 to 74.1%).					
35594940	1	79	dep	0	360:360	arg1	4					366:366	4	366:366	4	366:366	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	79	dep	0	360:360	arg1	%					384:384	10 wt%	379:384	10 wt%	379:384	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	79	dep	0	360:360	arg1	2					363:363	2	363:363	2	363:363	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	79	dep	0	360:360	arg1	8					372:372	8	372:372	8	372:372	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	79	dep	0	360:360	arg1	6					369:369	6	369:369	6	369:369	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	11	80	theme	food	1568:1571	arg1	applications					1583:1594	environmentally friendly food packaging applications	1543:1594	environmentally friendly food packaging applications	1543:1594	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	1	81	theme	arrowroot	310:318	arg1	AF					327:328	AF	327:328	AF	327:328	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	81	theme	arrowroot	310:318	arg1	fiber					320:324	arrowroot fiber	310:324	arrowroot fiber (AF)	310:329	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	82	dep	concentrations	344:357	arg1	0					360:360	0	360:360	0	360:360	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	10	83	theme	films	1390:1394	arg1	loss					1361:1364	the weight loss	1350:1364	the weight loss of TPAS/AF biocomposite films	1350:1394	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	10	83	theme	films	1390:1394	arg1	higher					1414:1419	higher	1414:1419	higher	1414:1419	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	9	84	theme	ATCC	1265:1268	arg1	coli					1259:1262	Escherichia coli	1247:1262	Escherichia coli (ATCC 25922)	1247:1275	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	9	84	theme	ATCC	1265:1268	arg1	25922					1270:1274	ATCC 25922	1265:1274	ATCC 25922	1265:1274	In addition, the incorporation of AF and control film showed an insignificant effect against three pathogenic bacteria, including Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 25922), and Bacillus subtilis (B29).					
35594940	3	85	theme	8.18 × 10-10 ×g.	881:896	arg1	s-1					898:900	8.18 × 10-10 ×g. s-1	881:900	8.18 × 10-10 ×g. s-1	881:900	Furthermore, increasing AF concentration led to a significant (p < 0.05) reduction in the linear burning rate and WVP of the biocomposite films from 248.9 to 115.2 mm/min and 8.18 × 10-10 ×g. s-1.					
35594940	11	86	theme	fiber	1477:1481	arg1	reinforcement					1450:1462	the reinforcement	1446:1462	the reinforcement of arrowroot fiber with TPAS film	1446:1496	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	10	87	theme	TPAS/AF	1369:1375	arg1	films					1390:1394	TPAS/AF biocomposite films	1369:1394	TPAS/AF biocomposite films	1369:1394	The soil burial findings demonstrated that the weight loss of TPAS/AF biocomposite films was significantly higher than TPAS film.					
35594940	11	88	theme	TPAS	1488:1491	arg1	film					1493:1496	TPAS film	1488:1496	TPAS film	1488:1496	Overall, the reinforcement of arrowroot fiber with TPAS film improved the properties of biocomposites for environmentally friendly food packaging applications.					
35594940	1	89	theme	thermoplastic	233:245	arg1	arrowroot					247:255	a novel biodegradable thermoplastic arrowroot	211:255	a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%)	211:385	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	89	theme	thermoplastic	233:245	arg1	arundinacea					266:276	Maranta arundinacea	258:276	Maranta arundinacea	258:276	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
35594940	1	90	theme	activity	455:462	arg1	terms					423:427	terms	423:427	terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties	423:548	Using the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties.					
36241306	4	0	theme	%	573:573	arg1	CS-TE					575:579	3.75 wt% CS-TE	566:579	3.75 wt% CS-TE	566:579	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	3	1	theme	novel	360:364	arg1	system					382:387	a novel flame-retardant system	358:387	a novel flame-retardant system	358:387	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	4	2	theme	excellent	732:740	arg1	behavior					756:763	excellent anti-dripping behavior	732:763	excellent anti-dripping behavior	732:763	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	4	3	theme	V-0	703:705	arg1	rating					707:712	a UL-94 V-0 rating	695:712	a UL-94 V-0 rating	695:712	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	4	4	theme	11.25 wt	585:592	arg1	AP					595:596	11.25 wt% AP	585:596	11.25 wt% AP	585:596	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	3	5	theme	flame-retardant	366:380	arg1	system					382:387	a novel flame-retardant system	358:387	a novel flame-retardant system	358:387	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	2	6	theme	droplets	297:304	arg1	droplets					297:304	molten droplets	290:304	molten droplets	290:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	2	6	theme	droplets	297:304	arg1	flammability					256:267	flammability	256:267	flammability	256:267	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	2	6	theme	droplets	297:304	arg1	amounts					279:285	large amounts	273:285	large amounts of molten droplets	273:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	3	7	theme	anti-dripping	537:549	arg1	property					551:558	anti-dripping property	537:558	anti-dripping property	537:558	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	4	8	theme	%	680:680	arg1	index					666:670	a limiting oxygen index	648:670	a limiting oxygen index of 28.5 %	648:680	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	2	9	theme	molten	290:295	arg1	droplets					297:304	molten droplets	290:304	molten droplets	290:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	5	10	theme	total	808:812	arg1	production					820:829	total smoke production	808:829	total smoke production	808:829	Meanwhile, the peak heat release rate and total smoke production decreased by 52.3 % and 73.4 % respectively.					
36241306	3	11	theme	chitosan	428:435	arg1	CS-TE					449:453	CS-TE	449:453	CS-TE	449:453	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	3	11	theme	chitosan	428:435	arg1	derivative					437:446	the as-prepared bio-based chitosan derivative	402:446	the as-prepared bio-based chitosan derivative (CS-TE)	402:454	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	4	12	theme	PLA	630:632	arg1	composite					634:642	the PLA composite	626:642	the PLA composite	626:642	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	4	13	theme	UL-94	697:701	arg1	rating					707:712	a UL-94 V-0 rating	695:712	a UL-94 V-0 rating	695:712	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	1	14	theme	various	204:210	arg1	fields					212:217	various fields	204:217	various fields	204:217	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	0	15	theme	anti-dripping	15:27	arg1	polylactide					49:59	anti-dripping and flame-retardant polylactide	15:59	anti-dripping and flame-retardant polylactide	15:59	Fabrication of anti-dripping and flame-retardant polylactide modified with chitosan derivative/aluminum hypophosphite.					
36241306	4	16	theme	3.75 wt	566:572	arg1	CS-TE					575:579	3.75 wt% CS-TE	566:579	3.75 wt% CS-TE	566:579	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	3	17	theme	flame	516:520	arg1	retardancy					522:531	the flame retardancy	512:531	the flame retardancy	512:531	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	1	18	theme	promising	129:137	arg1	polymer					153:159	a very promising biodegradable polymer	122:159	a very promising biodegradable polymer	122:159	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	1	18	theme	promising	129:137	arg1	acid					173:176	polylactic acid	162:176	polylactic acid (PLA)	162:182	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	5	19	theme	release	791:797	arg1	rate					799:802	the peak heat release rate	777:802	the peak heat release rate	777:802	Meanwhile, the peak heat release rate and total smoke production decreased by 52.3 % and 73.4 % respectively.					
36241306	0	20	theme	polylactide	49:59	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of anti-dripping and flame-retardant polylactide	0:59	Fabrication of anti-dripping and flame-retardant polylactide modified with chitosan derivative/aluminum hypophosphite.					
36241306	3	21	theme	aluminum	460:467	arg1	hypophosphite					469:481	aluminum hypophosphite	460:481	aluminum hypophosphite (AP)	460:486	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	3	21	theme	aluminum	460:467	arg1	AP					484:485	AP	484:485	AP	484:485	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	0	22	theme	flame-retardant	33:47	arg1	polylactide					49:59	anti-dripping and flame-retardant polylactide	15:59	anti-dripping and flame-retardant polylactide	15:59	Fabrication of anti-dripping and flame-retardant polylactide modified with chitosan derivative/aluminum hypophosphite.					
36241306	3	23	theme	as-prepared	406:416	arg1	CS-TE					449:453	CS-TE	449:453	CS-TE	449:453	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	3	23	theme	as-prepared	406:416	arg1	derivative					437:446	the as-prepared bio-based chitosan derivative	402:446	the as-prepared bio-based chitosan derivative (CS-TE)	402:454	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	5	24	theme	peak	781:784	arg1	rate					799:802	the peak heat release rate	777:802	the peak heat release rate	777:802	Meanwhile, the peak heat release rate and total smoke production decreased by 52.3 % and 73.4 % respectively.					
36241306	3	25	used	used	493:496	arg2	we					343:344	we	343:344	we	343:344	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	1	26	theme	biodegradable	139:151	arg1	polymer					153:159	a very promising biodegradable polymer	122:159	a very promising biodegradable polymer	122:159	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	1	26	theme	biodegradable	139:151	arg1	acid					173:176	polylactic acid	162:176	polylactic acid (PLA)	162:182	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	3	27	theme	bio-based	418:426	arg1	CS-TE					449:453	CS-TE	449:453	CS-TE	449:453	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	3	27	theme	bio-based	418:426	arg1	derivative					437:446	the as-prepared bio-based chitosan derivative	402:446	the as-prepared bio-based chitosan derivative (CS-TE)	402:454	In this work, we constructed a novel flame-retardant system by combining the as-prepared bio-based chitosan derivative (CS-TE) and aluminum hypophosphite (AP), and used it to improve the flame retardancy and anti-dripping property.					
36241306	4	28	contain	had	644:646	arg1	composite					634:642	the PLA composite	626:642	the PLA composite	626:642	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	4	28	contain	had	644:646	arg2	index					666:670	a limiting oxygen index	648:670	a limiting oxygen index of 28.5 %	648:680	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	4	29	theme	anti-dripping	742:754	arg1	behavior					756:763	excellent anti-dripping behavior	732:763	excellent anti-dripping behavior	732:763	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	2	30	theme	amounts	279:285	arg1	disadvantages					239:251	the disadvantages	235:251	the disadvantages of flammability and large amounts of molten droplets	235:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	2	31	theme	large	273:277	arg1	droplets					297:304	molten droplets	290:304	molten droplets	290:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	2	31	theme	large	273:277	arg1	amounts					279:285	large amounts	273:285	large amounts of molten droplets	273:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	1	32	theme	polylactic	162:171	arg1	PLA					179:181	PLA	179:181	PLA	179:181	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	1	32	theme	polylactic	162:171	arg1	polymer					153:159	a very promising biodegradable polymer	122:159	a very promising biodegradable polymer	122:159	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	1	32	theme	polylactic	162:171	arg1	acid					173:176	polylactic acid	162:176	polylactic acid (PLA)	162:182	As a very promising biodegradable polymer, polylactic acid (PLA) has been applied in various fields.					
36241306	4	33	theme	%	593:593	arg1	AP					595:596	11.25 wt% AP	585:596	11.25 wt% AP	585:596	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	0	34	theme	derivative/aluminum	84:102	arg1	hypophosphite					104:116	chitosan derivative/aluminum hypophosphite	75:116	chitosan derivative/aluminum hypophosphite	75:116	Fabrication of anti-dripping and flame-retardant polylactide modified with chitosan derivative/aluminum hypophosphite.					
36241306	5	35	theme	heat	786:789	arg1	rate					799:802	the peak heat release rate	777:802	the peak heat release rate	777:802	Meanwhile, the peak heat release rate and total smoke production decreased by 52.3 % and 73.4 % respectively.					
36241306	4	36	theme	oxygen	659:664	arg1	index					666:670	a limiting oxygen index	648:670	a limiting oxygen index of 28.5 %	648:680	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36241306	5	37	theme	smoke	814:818	arg1	production					820:829	total smoke production	808:829	total smoke production	808:829	Meanwhile, the peak heat release rate and total smoke production decreased by 52.3 % and 73.4 % respectively.					
36241306	0	38	theme	chitosan	75:82	arg1	hypophosphite					104:116	chitosan derivative/aluminum hypophosphite	75:116	chitosan derivative/aluminum hypophosphite	75:116	Fabrication of anti-dripping and flame-retardant polylactide modified with chitosan derivative/aluminum hypophosphite.					
36241306	2	39	theme	flammability	256:267	arg1	disadvantages					239:251	the disadvantages	235:251	the disadvantages of flammability and large amounts of molten droplets	235:304	Unfortunately, the disadvantages of flammability and large amounts of molten droplets limit its application.					
36241306	4	40	theme	limiting	650:657	arg1	index					666:670	a limiting oxygen index	648:670	a limiting oxygen index of 28.5 %	648:680	When 3.75 wt% CS-TE and 11.25 wt% AP were incorporated into PLA, the PLA composite had a limiting oxygen index of 28.5 % and achieved a UL-94 V-0 rating as well as showed excellent anti-dripping behavior.					
36436861	6	0	theme	Such	896:899	arg1	properties					901:910	Such properties	896:910	Such properties	896:910	Such properties are demonstrated in wearable, force mapping, multi-sensing and patternable electroluminescence devices.					
36436861	5	1	from	%	838:838	arg1	elongation					806:815	tailorable elongation	795:815	tailorable elongation	795:815	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	3	2	theme	core-shell	485:494	arg1	nanodroplets					499:510	colloidally stable core-shell LM nanodroplets	466:510	colloidally stable core-shell LM nanodroplets	466:510	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	1	3	theme	acrylic	236:242	arg1	acid					244:247	acrylic acid	236:247	acrylic acid (AA)	236:252	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	1	3	theme	acrylic	236:242	arg1	AA					250:251	AA	250:251	AA	250:251	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	0	4	theme	double	69:74	arg1	networks					76:83	double networks	69:83	double networks of bacterial cellulose hydrogels	69:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	2	5	link	crosslinked	306:316	arg1	hydrogel					328:335	a crosslinked composite hydrogel	304:335	a crosslinked composite hydrogel in which BNC exfoliates Mxene	304:365	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	3	6	theme	LM	496:497	arg1	nanodroplets					499:510	colloidally stable core-shell LM nanodroplets	466:510	colloidally stable core-shell LM nanodroplets	466:510	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	0	7	theme	bacterial	88:96	arg1	hydrogels					108:116	bacterial cellulose hydrogels	88:116	bacterial cellulose hydrogels	88:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	2	8	theme	fast	260:263	arg1	sonication					265:274	fast sonication	260:274	fast sonication	260:274	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	4	9	theme	surface	611:617	arg1	wrinkling					619:627	surface wrinkling	611:627	surface wrinkling	611:627	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	4	10	theme	Mxene	568:572	arg1	mechanism					540:548	the unique gelation mechanism	520:548	the unique gelation mechanism	520:548	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	4	10	theme	Mxene	568:572	arg1	effect					558:563	the effect	554:563	the effect of Mxene	554:572	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	0	11	theme	hydrogels	108:116	arg1	networks					76:83	double networks	69:83	double networks of bacterial cellulose hydrogels	69:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	5	12	theme	capabilities	882:893	arg1	ultra-elasticity					777:792	ultra-elasticity	777:792	ultra-elasticity (tailorable elongation, from 1000 % to 3200 %)	777:839	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	12	theme	capabilities	882:893	arg1	resistance					854:863	indentation resistance	842:863	indentation resistance	842:863	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	12	theme	capabilities	882:893	arg1	surfaces					767:774	surfaces	767:774	surfaces	767:774	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	12	theme	capabilities	882:893	arg1	capabilities					882:893	self-healing capabilities	869:893	self-healing capabilities	869:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	12	theme	capabilities	882:893	arg1	variety					756:762	a variety	754:762	a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities	754:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	13	theme	1000 	823:827	arg1	%					828:828	%	828:828	%	828:828	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	2	14	theme	conductive	386:395	arg1	pathways					397:404	organized conductive pathways	376:404	organized conductive pathways	376:404	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	1	15	theme	MXene	154:158	arg1	nanosheets					160:169	MXene nanosheets	154:169	MXene nanosheets	154:169	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	0	16	theme	cellulose	98:106	arg1	hydrogels					108:116	bacterial cellulose hydrogels	88:116	bacterial cellulose hydrogels	88:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	5	17	theme	self-healing	869:880	arg1	capabilities					882:893	self-healing capabilities	869:893	self-healing capabilities	869:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	18	dep	ultra-elasticity	777:792	arg1	elongation					806:815	tailorable elongation	795:815	tailorable elongation	795:815	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	19	theme	tailorable	795:804	arg1	elongation					806:815	tailorable elongation	795:815	tailorable elongation	795:815	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	20	theme	3200 	833:837	arg1	%					828:828	%	828:828	%	828:828	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	2	21	theme	AA	277:278	arg1	polymerization					280:293	AA polymerization	277:293	AA polymerization	277:293	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	6	22	theme	electroluminescence	987:1005	arg1	devices					1007:1013	electroluminescence devices	987:1013	electroluminescence devices	987:1013	Such properties are demonstrated in wearable, force mapping, multi-sensing and patternable electroluminescence devices.					
36436861	3	23	theme	Soft	407:410	arg1	properties					423:432	Soft conducting properties	407:432	Soft conducting properties	407:432	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	4	24	theme	gelation	531:538	arg1	mechanism					540:548	the unique gelation mechanism	520:548	the unique gelation mechanism	520:548	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	3	25	dep	nanodroplets	499:510	arg1	presence					454:461	presence	454:461	presence	454:461	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	3	25	dep	nanodroplets	499:510	arg1	the					450:452	the	450:452	the	450:452	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	6	26	theme	force	942:946	arg1	mapping					948:954	force mapping	942:954	force mapping	942:954	Such properties are demonstrated in wearable, force mapping, multi-sensing and patternable electroluminescence devices.					
36436861	2	27	theme	composite	318:326	arg1	hydrogel					328:335	a crosslinked composite hydrogel	304:335	a crosslinked composite hydrogel in which BNC exfoliates Mxene	304:365	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	1	28	theme	sulfonated	191:200	arg1	BNC					227:229	BNC	227:229	BNC	227:229	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	1	28	theme	sulfonated	191:200	arg1	nanocellulose					212:224	sulfonated bacterial nanocellulose	191:224	sulfonated bacterial nanocellulose (BNC)	191:230	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	0	29	theme	self-healing	30:41	arg1	electronics					48:58	self-healing soft electronics	30:58	self-healing soft electronics based on double networks of bacterial cellulose hydrogels	30:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	3	30	theme	stable	478:483	arg1	nanodroplets					499:510	colloidally stable core-shell LM nanodroplets	466:510	colloidally stable core-shell LM nanodroplets	466:510	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	1	31	theme	bacterial	202:210	arg1	BNC					227:229	BNC	227:229	BNC	227:229	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	1	31	theme	bacterial	202:210	arg1	nanocellulose					212:224	sulfonated bacterial nanocellulose	191:224	sulfonated bacterial nanocellulose (BNC)	191:230	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	4	32	theme	electrical	651:660	arg1	GF = 8.09					675:683	GF = 8.09	675:683	GF = 8.09	675:683	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	4	32	theme	electrical	651:660	arg1	sensitivity					662:672	their electrical sensitivity	645:672	their electrical sensitivity (GF = 8.09)	645:684	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	2	33	theme	organized	376:384	arg1	pathways					397:404	organized conductive pathways	376:404	organized conductive pathways	376:404	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	3	34	theme	conducting	412:421	arg1	properties					423:432	Soft conducting properties	407:432	Soft conducting properties	407:432	Soft conducting properties are achieved in the presence of colloidally stable core-shell LM nanodroplets.					
36436861	5	35	theme	surfaces	767:774	arg1	ultra-elasticity					777:792	ultra-elasticity	777:792	ultra-elasticity (tailorable elongation, from 1000 % to 3200 %)	777:839	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	35	theme	surfaces	767:774	arg1	resistance					854:863	indentation resistance	842:863	indentation resistance	842:863	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	35	theme	surfaces	767:774	arg1	surfaces					767:774	surfaces	767:774	surfaces	767:774	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	35	theme	surfaces	767:774	arg1	capabilities					882:893	self-healing capabilities	869:893	self-healing capabilities	869:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	35	theme	surfaces	767:774	arg1	variety					756:762	a variety	754:762	a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities	754:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	6	36	dep	wearable	932:939	arg1	devices					1007:1013	electroluminescence devices	987:1013	electroluminescence devices	987:1013	Such properties are demonstrated in wearable, force mapping, multi-sensing and patternable electroluminescence devices.					
36436861	5	37	theme	interfacial	730:740	arg1	adhesion					742:749	interfacial adhesion	730:749	interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities	730:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	38	theme	ultra-elasticity	777:792	arg1	ultra-elasticity					777:792	ultra-elasticity	777:792	ultra-elasticity (tailorable elongation, from 1000 % to 3200 %)	777:839	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	38	theme	ultra-elasticity	777:792	arg1	resistance					854:863	indentation resistance	842:863	indentation resistance	842:863	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	38	theme	ultra-elasticity	777:792	arg1	surfaces					767:774	surfaces	767:774	surfaces	767:774	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	38	theme	ultra-elasticity	777:792	arg1	capabilities					882:893	self-healing capabilities	869:893	self-healing capabilities	869:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	38	theme	ultra-elasticity	777:792	arg1	variety					756:762	a variety	754:762	a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities	754:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	2	39	theme	crosslinked	306:316	arg1	hydrogel					328:335	a crosslinked composite hydrogel	304:335	a crosslinked composite hydrogel in which BNC exfoliates Mxene	304:365	Upon fast sonication, AA polymerization leads to a crosslinked composite hydrogel in which BNC exfoliates Mxene, forming organized conductive pathways.					
36436861	0	40	theme	soft	43:46	arg1	electronics					48:58	self-healing soft electronics	30:58	self-healing soft electronics based on double networks of bacterial cellulose hydrogels	30:116	Liquid metal and Mxene enable self-healing soft electronics based on double networks of bacterial cellulose hydrogels.					
36436861	4	41	theme	unique	524:529	arg1	mechanism					540:548	the unique gelation mechanism	520:548	the unique gelation mechanism	520:548	Due to the unique gelation mechanism and the effect of Mxene, the hydrogels spontaneously undergo surface wrinkling, which improves their electrical sensitivity (GF = 8.09).					
36436861	1	42	theme	Liquid	119:124	arg1	nanodroplets					137:148	Liquid metal (LM) nanodroplets	119:148	Liquid metal (LM) nanodroplets	119:148	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	1	42	theme	Liquid	119:124	arg1	LM					133:134	LM	133:134	LM	133:134	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	5	43	dep	%	828:828	arg1	to					830:831	to	830:831	to	830:831	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	1	44	theme	metal	126:130	arg1	nanodroplets					137:148	Liquid metal (LM) nanodroplets	119:148	Liquid metal (LM) nanodroplets	119:148	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	1	44	theme	metal	126:130	arg1	LM					133:134	LM	133:134	LM	133:134	Liquid metal (LM) nanodroplets and MXene nanosheets are integrated with sulfonated bacterial nanocellulose (BNC) and acrylic acid (AA).					
36436861	5	45	theme	indentation	842:852	arg1	resistance					854:863	indentation resistance	842:863	indentation resistance	842:863	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	46	theme	resistance	854:863	arg1	ultra-elasticity					777:792	ultra-elasticity	777:792	ultra-elasticity (tailorable elongation, from 1000 % to 3200 %)	777:839	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	46	theme	resistance	854:863	arg1	resistance					854:863	indentation resistance	842:863	indentation resistance	842:863	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	46	theme	resistance	854:863	arg1	surfaces					767:774	surfaces	767:774	surfaces	767:774	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	46	theme	resistance	854:863	arg1	capabilities					882:893	self-healing capabilities	869:893	self-healing capabilities	869:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
36436861	5	46	theme	resistance	854:863	arg1	variety					756:762	a variety	754:762	a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities	754:893	The hydrogels are further shown to display interfacial adhesion to a variety of surfaces, ultra-elasticity (tailorable elongation, from 1000 % to 3200 %), indentation resistance and self-healing capabilities.					
35916935	2	0	theme	environmental	484:496	arg1	stability					498:506	environmental stability	484:506	environmental stability	484:506	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	4	1	from	/ppm	779:782	arg1	range					791:795	the range	787:795	the range of 0.2-3 ppm	787:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	8	2	with	sensing	1360:1366	arg1	sensitivity					1425:1435	high sensitivity	1420:1435	high sensitivity	1420:1435	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	8	2	with	sensing	1360:1366	arg1	consumption					1383:1393	low power consumption	1373:1393	low power consumption	1373:1393	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	8	2	with	sensing	1360:1366	arg1	reaction					1406:1413	superfast reaction	1396:1413	superfast reaction	1396:1413	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	4	3	theme	PEDOT	921:925	arg1	counterparts					931:942	pure PEDOT:PSS counterparts	916:942	pure PEDOT:PSS counterparts	916:942	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	4	theme	NH3	834:836	arg1	sensing					838:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	1	5	theme	minor	240:244	arg1	consumption					253:263	minor energy consumption	240:263	minor energy consumption especially	240:274	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	8	6	theme	NH3	1356:1358	arg1	sensing					1360:1366	trace NH3 sensing	1350:1366	trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity	1350:1435	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	4	7	theme	/ppm	779:782	arg1	sensitivity					758:768	sensitivity	758:768	sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm	758:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	5	8	theme	polymers	1054:1061	arg1	cases					1034:1038	the best cases	1025:1038	the best cases of conducting polymers based NH3 sensors	1025:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	6	9	theme	response	1122:1129	arg1	enhancement					1131:1141	more than twofold response enhancement	1104:1141	more than twofold response enhancement indicated a huge potential in exhaled breath monitoring	1104:1197	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	4	10	theme	sensitive	747:755	arg1	sensing					838:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	1	11	theme	energy	246:251	arg1	consumption					253:263	minor energy consumption	240:263	minor energy consumption especially	240:274	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	8	12	theme	trace	1350:1354	arg1	sensing					1360:1366	trace NH3 sensing	1350:1366	trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity	1350:1435	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	5	13	theme	best	1029:1032	arg1	cases					1034:1038	the best cases	1025:1038	the best cases of conducting polymers based NH3 sensors	1025:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	8	14	theme	alternative	1325:1335	arg1	strategy					1337:1344	an alternative strategy	1322:1344	an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity	1322:1435	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	1	15	from	temperature	146:156	arg1	detection					128:136	Chemiresistive ammonia (NH3) detection	99:136	Chemiresistive ammonia (NH3) detection at room temperature	99:156	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	6	16	theme	twofold	1114:1120	arg1	enhancement					1131:1141	more than twofold response enhancement	1104:1141	more than twofold response enhancement indicated a huge potential in exhaled breath monitoring	1104:1197	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	1	17	theme	consumption	253:263	arg1	merits					194:199	the unique merits	183:199	the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics	183:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	4	18	from	sensitivity	758:768	arg1	range					791:795	the range	787:795	the range of 0.2-3 ppm	787:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	19	theme	%	778:778	arg1	/ppm					779:782	∼7.46%/ppm	773:782	∼7.46%/ppm in the range of 0.2-3 ppm	773:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	20	theme	baseline	896:903	arg1	drift					905:909	less baseline drift	891:909	less baseline drift	891:909	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	21	theme	selective	812:820	arg1	sensing					838:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	22	theme	∼7.46	773:777	arg1	%					778:778	%	778:778	%	778:778	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	5	23	theme	conducting	1043:1052	arg1	NH3					1069:1071	NH3	1069:1071	NH3	1069:1071	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	5	23	theme	conducting	1043:1052	arg1	polymers					1054:1061	conducting polymers	1043:1061	conducting polymers based NH3 sensors	1043:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	5	23	theme	conducting	1043:1052	arg1	sensors					1073:1079	sensors	1073:1079	sensors	1073:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	4	24	theme	stable	827:832	arg1	sensing					838:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing	747:844	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	4	25	theme	pure	916:919	arg1	counterparts					931:942	pure PEDOT:PSS counterparts	916:942	pure PEDOT:PSS counterparts	916:942	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	1	26	theme	Chemiresistive	99:112	arg1	detection					128:136	Chemiresistive ammonia (NH3) detection	99:136	Chemiresistive ammonia (NH3) detection at room temperature	99:156	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	3	27	dep	overcome	597:604	arg1	PSS					667:669	PSS	667:669	PSS via a facile blending	667:691	To overcome these, we incorporated cellulose nanofibers (CNF) into PEDOT:PSS via a facile blending.					
35916935	0	28	theme	Mesoporous	0:9	arg1	cellulose					11:19	Mesoporous cellulose	0:19	Mesoporous cellulose	0:19	Mesoporous cellulose nanofibers-interlaced PEDOT:PSS hybrids for chemiresistive ammonia detection.					
35916935	4	29	theme	constituent-optimized	698:718	arg1	sensor					730:735	The constituent-optimized composite sensor	694:735	The constituent-optimized composite sensor	694:735	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	1	30	theme	ammonia	114:120	arg1	detection					128:136	Chemiresistive ammonia (NH3) detection	99:136	Chemiresistive ammonia (NH3) detection at room temperature	99:156	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	1	31	theme	unique	187:192	arg1	merits					194:199	the unique merits	183:199	the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics	183:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	0	32	theme	PEDOT	43:47	arg1	hybrids					53:59	PEDOT:PSS hybrids	43:59	PEDOT:PSS hybrids for chemiresistive ammonia detection	43:96	Mesoporous cellulose nanofibers-interlaced PEDOT:PSS hybrids for chemiresistive ammonia detection.					
35916935	2	33	dep	poly	331:334	arg1	PEDOT					386:390	PEDOT	386:390	PEDOT:PSS	386:394	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	2	33	dep	poly	331:334	arg1	polystyrenesulfonate					364:383	polystyrenesulfonate	364:383	poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS)	331:395	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	8	34	theme	low	1373:1375	arg1	consumption					1383:1393	low power consumption	1373:1393	low power consumption	1373:1393	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	7	35	theme	performance	1259:1269	arg1	features					1293:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	Furthermore, we observed an excellent flexible NH3-sensing performance with bending-tolerant features.					
35916935	2	36	theme	considerable	409:420	arg1	attention					422:430	considerable attention	409:430	considerable attention due to the benign room-temperature conductivity and environmental stability	409:506	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	1	37	theme	portable	280:287	arg1	electronics					302:312	portable and wearable electronics	280:312	portable and wearable electronics	280:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	2	38	theme	limited	542:548	arg1	sensitivity					550:560	limited sensitivity	542:560	limited sensitivity	542:560	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	8	39	theme	high	1420:1423	arg1	sensitivity					1425:1435	high sensitivity	1420:1435	high sensitivity	1420:1435	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	1	40	theme	NH3	123:125	arg1	detection					128:136	Chemiresistive ammonia (NH3) detection	99:136	Chemiresistive ammonia (NH3) detection at room temperature	99:156	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	7	41	theme	with bending-tolerant	1271:1291	arg1	features					1293:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	Furthermore, we observed an excellent flexible NH3-sensing performance with bending-tolerant features.					
35916935	0	42	theme	PSS	49:51	arg1	hybrids					53:59	PEDOT:PSS hybrids	43:59	PEDOT:PSS hybrids for chemiresistive ammonia detection	43:96	Mesoporous cellulose nanofibers-interlaced PEDOT:PSS hybrids for chemiresistive ammonia detection.					
35916935	5	43	dep	based	1063:1067	arg1	NH3					1069:1071	NH3	1069:1071	NH3	1069:1071	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	5	43	dep	based	1063:1067	arg1	polymers					1054:1061	conducting polymers	1043:1061	conducting polymers based NH3 sensors	1043:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	5	43	dep	based	1063:1067	arg1	sensors					1073:1079	sensors	1073:1079	sensors	1073:1079	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	7	44	theme	flexible	1238:1245	arg1	features					1293:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	Furthermore, we observed an excellent flexible NH3-sensing performance with bending-tolerant features.					
35916935	4	45	theme	0.2-3 ppm	800:808	arg1	range					791:795	the range	787:795	the range of 0.2-3 ppm	787:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	7	46	theme	NH3-sensing	1247:1257	arg1	features					1293:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	Furthermore, we observed an excellent flexible NH3-sensing performance with bending-tolerant features.					
35916935	1	47	theme	easy	204:207	arg1	miniaturization					209:223	easy miniaturization	204:223	easy miniaturization	204:223	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	2	48	theme	room-temperature	450:465	arg1	conductivity					467:478	the benign room-temperature conductivity	439:478	the benign room-temperature conductivity	439:478	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	1	49	theme	wearable	293:300	arg1	electronics					302:312	portable and wearable electronics	280:312	portable and wearable electronics	280:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	4	50	theme	PSS	927:929	arg1	counterparts					931:942	pure PEDOT:PSS counterparts	916:942	pure PEDOT:PSS counterparts	916:942	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	6	51	theme	exhaled	1173:1179	arg1	breath					1181:1186	exhaled breath	1173:1186	exhaled breath monitoring	1173:1197	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	1	52	theme	miniaturization	209:223	arg1	merits					194:199	the unique merits	183:199	the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics	183:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	2	53	theme	benign	443:448	arg1	conductivity					467:478	the benign room-temperature conductivity	439:478	the benign room-temperature conductivity	439:478	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	4	54	theme	55	858:859	arg1	%					860:860	%	860:860	%	860:860	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	5	55	theme	response/recovery	963:979	arg1	NH3					1013:1015	4.9 s/5.2 s toward 1 ppm NH3	988:1015	4.9 s/5.2 s toward 1 ppm NH3	988:1015	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	5	55	theme	response/recovery	963:979	arg1	times					981:985	the response/recovery times	959:985	the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3)	959:1016	Additionally, the response/recovery times (4.9 s/5.2 s toward 1 ppm NH3) ranked the best cases of conducting polymers based NH3 sensors.					
35916935	4	56	theme	higher	871:876	arg1	response					878:885	higher response	871:885	higher response	871:885	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	2	57	theme	reaction	575:582	arg1	kinetics					584:591	sluggish reaction kinetics	566:591	sluggish reaction kinetics	566:591	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	4	58	from	RH	862:863	arg1	25 °C					849:853	25 °C	849:853	25 °C at 55% RH	849:863	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	8	59	theme	power	1377:1381	arg1	consumption					1383:1393	low power consumption	1373:1393	low power consumption	1373:1393	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	4	60	dep	sensitive	747:755	arg1	sensitivity					758:768	sensitivity	758:768	sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm	758:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	2	61	theme	sluggish	566:573	arg1	kinetics					584:591	sluggish reaction kinetics	566:591	sluggish reaction kinetics	566:591	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
35916935	8	62	theme	superfast	1396:1404	arg1	reaction					1406:1413	superfast reaction	1396:1413	superfast reaction	1396:1413	This work provides an alternative strategy for trace NH3 sensing with low power consumption, superfast reaction, and high sensitivity.					
35916935	6	63	theme	huge	1155:1158	arg1	potential					1160:1168	a huge potential	1153:1168	a huge potential in exhaled breath monitoring	1153:1197	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	4	64	theme	composite	720:728	arg1	sensor					730:735	The constituent-optimized composite sensor	694:735	The constituent-optimized composite sensor	694:735	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	6	65	from	potential	1160:1168	arg1	breath					1181:1186	exhaled breath	1173:1186	exhaled breath monitoring	1173:1197	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	4	66	theme	%	860:860	arg1	RH					862:863	55% RH	858:863	55% RH	858:863	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	7	67	theme	excellent	1228:1236	arg1	features					1293:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	an excellent flexible NH3-sensing performance with bending-tolerant features	1225:1300	Furthermore, we observed an excellent flexible NH3-sensing performance with bending-tolerant features.					
35916935	3	68	theme	cellulose	629:637	arg1	CNF					651:653	CNF	651:653	CNF	651:653	To overcome these, we incorporated cellulose nanofibers (CNF) into PEDOT:PSS via a facile blending.					
35916935	3	68	theme	cellulose	629:637	arg1	nanofibers					639:648	cellulose nanofibers	629:648	cellulose nanofibers (CNF)	629:654	To overcome these, we incorporated cellulose nanofibers (CNF) into PEDOT:PSS via a facile blending.					
35916935	4	69	from	range	791:795	arg1	sensitivity					758:768	sensitivity	758:768	sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm	758:808	The constituent-optimized composite sensor displayed sensitive (sensitivity of ∼7.46%/ppm in the range of 0.2-3 ppm), selective, and stable NH3 sensing at 25 °C at 55% RH, with higher response and less baseline drift than pure PEDOT:PSS counterparts.					
35916935	1	70	theme	room	141:144	arg1	temperature					146:156	room temperature	141:156	room temperature	141:156	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	1	71	theme	low	226:228	arg1	cost					230:233	low cost	226:233	low cost	226:233	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	0	72	theme	ammonia	80:86	arg1	detection					88:96	chemiresistive ammonia detection	65:96	chemiresistive ammonia detection	65:96	Mesoporous cellulose nanofibers-interlaced PEDOT:PSS hybrids for chemiresistive ammonia detection.					
35916935	6	73	dep	twofold	1114:1120	arg1	than					1109:1112	than	1109:1112	than	1109:1112	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	6	73	dep	twofold	1114:1120	arg1	more					1104:1107	more	1104:1107	more	1104:1107	The humidity involved more than twofold response enhancement indicated a huge potential in exhaled breath monitoring.					
35916935	1	74	theme	cost	230:233	arg1	merits					194:199	the unique merits	183:199	the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics	183:312	Chemiresistive ammonia (NH3) detection at room temperature is highly desired due to the unique merits of easy miniaturization, low cost, and minor energy consumption especially for portable and wearable electronics.					
35916935	0	75	theme	chemiresistive	65:78	arg1	detection					88:96	chemiresistive ammonia detection	65:96	chemiresistive ammonia detection	65:96	Mesoporous cellulose nanofibers-interlaced PEDOT:PSS hybrids for chemiresistive ammonia detection.					
35916935	3	76	theme	facile	677:682	arg1	blending					684:691	a facile blending	675:691	a facile blending	675:691	To overcome these, we incorporated cellulose nanofibers (CNF) into PEDOT:PSS via a facile blending.					
35916935	2	77	dep	PEDOT	386:390	arg1	PSS					392:394	PSS	392:394	PEDOT:PSS	386:394	In this regard, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) has sparked considerable attention due to the benign room-temperature conductivity and environmental stability, but it is undesirably impeded by limited sensitivity and sluggish reaction kinetics.					
36200299	4	0	dep	meanwhile	792:800	arg1	in					803:804	in	803:804	in	803:804	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	1	1	theme	thermal	189:195	arg1	process					211:217	thermal decomposition process	189:217	thermal decomposition process	189:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	1	2	theme	decomposition	197:209	arg1	process					211:217	thermal decomposition process	189:217	thermal decomposition process	189:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	4	3	theme	heat	867:870	arg1	flow					872:875	heat flow	867:875	heat flow	867:875	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	3	4	theme	microfluidic	631:642	arg1	technique					653:661	microfluidic spinning technique	631:661	microfluidic spinning technique	631:661	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	3	5	theme	CaCO3	583:587	arg1	fiber					622:626	CaCO3 nanoparticle-reinforced alginate fiber	583:626	CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique	583:661	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	4	6	theme	Comparative	664:674	arg1	analysis					676:683	Comparative analysis	664:683	Comparative analysis	664:683	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	2	7	theme	fire-resistant	343:356	arg1	material					372:379	an intrinsic fire-resistant biodegradable material	330:379	an intrinsic fire-resistant biodegradable material	330:379	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	7	theme	fire-resistant	343:356	arg1	polysaccharide					293:306	A natural polysaccharide	283:306	A natural polysaccharide	283:306	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	6	8	theme	heat	1216:1219	arg1	transmission					1221:1232	heat transmission	1216:1232	heat transmission	1216:1232	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	3	9	theme	nanoparticle-reinforced	589:611	arg1	fiber					622:626	CaCO3 nanoparticle-reinforced alginate fiber	583:626	CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique	583:661	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	1	10	from	compounds	176:184	arg1	process					211:217	thermal decomposition process	189:217	thermal decomposition process	189:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	2	11	theme	limited	390:396	arg1	performance					409:419	its limited mechanical performance	386:419	its limited mechanical performance	386:419	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	1	12	theme	organic	168:174	arg1	compounds					176:184	toxic volatile organic compounds	153:184	toxic volatile organic compounds in thermal decomposition process	153:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	4	13	theme	mechanical	768:777	arg1	performance					779:789	its mechanical performance	764:789	its mechanical performance	764:789	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	4	14	theme	meanwhile	792:800	arg1	nanoparticles					827:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	4	15	theme	excellent	913:921	arg1	retardancy					929:938	excellent flame retardancy	913:938	excellent flame retardancy	913:938	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	4	16	theme	generated	811:819	arg1	nanoparticles					827:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	2	17	theme	calcium	309:315	arg1	alginate					317:324	calcium alginate	309:324	calcium alginate	309:324	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	17	theme	calcium	309:315	arg1	polysaccharide					293:306	A natural polysaccharide	283:306	A natural polysaccharide	283:306	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	5	18	theme	prepared	945:952	arg1	fiber					964:968	The prepared composite fiber	941:968	The prepared composite fiber	941:968	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	6	19	theme	pyrolysis	1105:1113	arg1	effect					1187:1192	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	19	theme	pyrolysis	1105:1113	arg1	barrier					1151:1157	the physical barrier	1138:1157	the physical barrier	1138:1157	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	19	theme	pyrolysis	1105:1113	arg1	products					1115:1122	The formed residue char and pyrolysis products	1077:1122	products	1115:1122	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	19	theme	pyrolysis	1105:1113	arg1	char					1096:1099	The formed residue char and pyrolysis products	1077:1122	char	1096:1099	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	5	20	theme	toxic	1001:1005	arg1	compounds					1024:1032	toxic volatile organic compounds	1001:1032	toxic volatile organic compounds	1001:1032	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	7	21	dep	good	1335:1338	arg1	mechanical					1340:1349	mechanical	1340:1349	mechanical	1340:1349	All of the results demonstrate that the obtained fiber exhibits a good mechanical and flame-retardant performance, making it an ideal candidate as a fire-protection textile.					
36200299	6	22	theme	physical	1142:1149	arg1	effect					1187:1192	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	22	theme	physical	1142:1149	arg1	barrier					1151:1157	the physical barrier	1138:1157	the physical barrier	1138:1157	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	22	theme	physical	1142:1149	arg1	products					1115:1122	The formed residue char and pyrolysis products	1077:1122	products	1115:1122	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	22	theme	physical	1142:1149	arg1	char					1096:1099	The formed residue char and pyrolysis products	1077:1122	char	1096:1099	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	2	23	theme	intrinsic	333:341	arg1	material					372:379	an intrinsic fire-resistant biodegradable material	330:379	an intrinsic fire-resistant biodegradable material	330:379	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	23	theme	intrinsic	333:341	arg1	polysaccharide					293:306	A natural polysaccharide	283:306	A natural polysaccharide	283:306	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	1	24	theme	Petroleum-based	100:114	arg1	fiber					138:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	7	25	theme	good	1335:1338	arg1	performance					1371:1381	a good mechanical and flame-retardant performance	1333:1381	a good mechanical and flame-retardant performance	1333:1381	All of the results demonstrate that the obtained fiber exhibits a good mechanical and flame-retardant performance, making it an ideal candidate as a fire-protection textile.					
36200299	4	26	theme	Na2CO3	725:730	arg1	incorporation					702:714	incorporation	702:714	incorporation of 0.50% Na2CO3 into the fiber	702:745	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	0	27	theme	In	0:1	arg1	Nanoparticles					25:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	5	28	dep	less	979:982	arg1	compounds					1024:1032	toxic volatile organic compounds	1001:1032	toxic volatile organic compounds	1001:1032	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	5	28	dep	less	979:982	arg1	smoke					990:994	smoke	990:994	smoke	990:994	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	5	28	dep	less	979:982	arg1	heat					984:987	heat	984:987	heat	984:987	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	4	29	theme	flame	923:927	arg1	retardancy					929:938	excellent flame retardancy	913:938	excellent flame retardancy	913:938	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	1	30	theme	synthetic	116:124	arg1	fiber					138:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	7	31	theme	flame-retardant	1355:1369	arg1	performance					1371:1381	a good mechanical and flame-retardant performance	1333:1381	a good mechanical and flame-retardant performance	1333:1381	All of the results demonstrate that the obtained fiber exhibits a good mechanical and flame-retardant performance, making it an ideal candidate as a fire-protection textile.					
36200299	1	32	theme	other	227:231	arg1	problems					233:240	other problems	227:240	other problems	227:240	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	0	33	theme	CaCO3	19:23	arg1	Nanoparticles					25:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	1	34	theme	flame-proof	126:136	arg1	fiber					138:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	4	35	theme	0.50	719:722	arg1	%					723:723	%	723:723	%	723:723	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	0	36	theme	Generating	8:17	arg1	Nanoparticles					25:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles	0:37	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	6	37	theme	further	1249:1255	arg1	combustion					1257:1266	the further combustion	1245:1266	the further combustion	1245:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	5	38	theme	volatile	1007:1014	arg1	compounds					1024:1032	toxic volatile organic compounds	1001:1032	toxic volatile organic compounds	1001:1032	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	5	39	theme	organic	1016:1022	arg1	compounds					1024:1032	toxic volatile organic compounds	1001:1032	toxic volatile organic compounds	1001:1032	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	4	40	theme	CaCO3	821:825	arg1	nanoparticles					827:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	meanwhile, in situ generated CaCO3 nanoparticles	792:839	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	2	41	theme	flame-retardant	456:470	arg1	fabric					472:477	a practical flame-retardant fabric	444:477	a practical flame-retardant fabric	444:477	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	3	42	theme	spinning	536:543	arg1	solution					545:552	alginate spinning solution	527:552	alginate spinning solution	527:552	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	1	43	contain	has	223:225	arg2	problems					233:240	other problems	227:240	other problems	227:240	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	1	43	contain	has	223:225	arg1	fiber					138:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber	100:142	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	5	44	theme	composite	954:962	arg1	fiber					964:968	The prepared composite fiber	941:968	The prepared composite fiber	941:968	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	2	45	theme	practical	446:454	arg1	fabric					472:477	a practical flame-retardant fabric	444:477	a practical flame-retardant fabric	444:477	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	6	46	theme	residue	1088:1094	arg1	effect					1187:1192	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	46	theme	residue	1088:1094	arg1	char					1096:1099	The formed residue char and pyrolysis products	1077:1122	char	1096:1099	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	46	theme	residue	1088:1094	arg1	products					1115:1122	The formed residue char and pyrolysis products	1077:1122	products	1115:1122	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	46	theme	residue	1088:1094	arg1	barrier					1151:1157	the physical barrier	1138:1157	the physical barrier	1138:1157	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	7	47	theme	ideal	1397:1401	arg1	candidate					1403:1411	an ideal candidate	1394:1411	an ideal candidate as a fire-protection textile	1394:1440	All of the results demonstrate that the obtained fiber exhibits a good mechanical and flame-retardant performance, making it an ideal candidate as a fire-protection textile.					
36200299	1	48	theme	tickling	248:255	arg1	feeling					257:263	tickling feeling	248:263	tickling feeling	248:263	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	0	49	theme	Calcium	63:69	arg1	Fiber					93:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	3	50	theme	spinning	644:651	arg1	technique					653:661	microfluidic spinning technique	631:661	microfluidic spinning technique	631:661	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	3	51	theme	alginate	527:534	arg1	solution					545:552	alginate spinning solution	527:552	alginate spinning solution	527:552	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	0	52	theme	Nonflammable	50:61	arg1	Fiber					93:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	7	53	theme	obtained	1309:1316	arg1	fiber					1318:1322	the obtained fiber	1305:1322	the obtained fiber	1305:1322	All of the results demonstrate that the obtained fiber exhibits a good mechanical and flame-retardant performance, making it an ideal candidate as a fire-protection textile.					
36200299	1	54	theme	toxic	153:157	arg1	compounds					176:184	toxic volatile organic compounds	153:184	toxic volatile organic compounds in thermal decomposition process	153:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	4	55	dep	in	803:804	arg1	situ					806:809	situ	806:809	situ	806:809	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	1	56	theme	volatile	159:166	arg1	compounds					176:184	toxic volatile organic compounds	153:184	toxic volatile organic compounds in thermal decomposition process	153:217	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	3	57	theme	alginate	613:620	arg1	fiber					622:626	CaCO3 nanoparticle-reinforced alginate fiber	583:626	CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique	583:661	To address this problem, Na2CO3 was doped into alginate spinning solution to obtain in situ generating CaCO3 nanoparticle-reinforced alginate fiber by microfluidic spinning technique.					
36200299	4	58	with	fiber	902:906	arg1	retardancy					929:938	excellent flame retardancy	913:938	excellent flame retardancy	913:938	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	6	59	theme	synergistic	1175:1185	arg1	effect					1187:1192	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	59	theme	synergistic	1175:1185	arg1	barrier					1151:1157	the physical barrier	1138:1157	the physical barrier	1138:1157	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	59	theme	synergistic	1175:1185	arg1	products					1115:1122	The formed residue char and pyrolysis products	1077:1122	products	1115:1122	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	59	theme	synergistic	1175:1185	arg1	char					1096:1099	The formed residue char and pyrolysis products	1077:1122	char	1096:1099	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	2	60	theme	natural	285:291	arg1	alginate					317:324	calcium alginate	309:324	calcium alginate	309:324	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	60	theme	natural	285:291	arg1	material					372:379	an intrinsic fire-resistant biodegradable material	330:379	an intrinsic fire-resistant biodegradable material	330:379	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	60	theme	natural	285:291	arg1	polysaccharide					293:306	A natural polysaccharide	283:306	A natural polysaccharide	283:306	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	61	theme	biodegradable	358:370	arg1	material					372:379	an intrinsic fire-resistant biodegradable material	330:379	an intrinsic fire-resistant biodegradable material	330:379	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	2	61	theme	biodegradable	358:370	arg1	polysaccharide					293:306	A natural polysaccharide	283:306	A natural polysaccharide	283:306	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
36200299	6	62	theme	formed	1081:1086	arg1	effect					1187:1192	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion	1173:1266	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	62	theme	formed	1081:1086	arg1	char					1096:1099	The formed residue char and pyrolysis products	1077:1122	char	1096:1099	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	62	theme	formed	1081:1086	arg1	products					1115:1122	The formed residue char and pyrolysis products	1077:1122	products	1115:1122	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	6	62	theme	formed	1081:1086	arg1	barrier					1151:1157	the physical barrier	1138:1157	the physical barrier	1138:1157	The formed residue char and pyrolysis products functioned as the physical barrier and displayed a synergistic effect to inhibit oxygen and heat transmission and impede the further combustion.					
36200299	0	63	theme	Biocomposite	80:91	arg1	Fiber					93:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	4	64	theme	%	723:723	arg1	Na2CO3					725:730	0.50% Na2CO3	719:730	0.50% Na2CO3	719:730	Comparative analysis illustrated that incorporation of 0.50% Na2CO3 into the fiber greatly improved its mechanical performance; meanwhile, in situ generated CaCO3 nanoparticles also throttled oxygen and heat flow in burning, endowing the fiber with excellent flame retardancy.					
36200299	5	65	theme	fire	1064:1067	arg1	hazard					1069:1074	the fire hazard	1060:1074	the fire hazard	1060:1074	The prepared composite fiber released less heat, smoke, and toxic volatile organic compounds in burning, which reduced the fire hazard.					
36200299	1	66	theme	high	269:272	arg1	density					274:280	high density	269:280	high density	269:280	Petroleum-based synthetic flame-proof fiber releases toxic volatile organic compounds in thermal decomposition process and has other problems, like tickling feeling and high density.					
36200299	0	67	theme	Alginate	71:78	arg1	Fiber					93:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	Nonflammable Calcium Alginate Biocomposite Fiber	50:97	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	0	68	dep	In	0:1	arg1	Situ					3:6	Situ	3:6	Situ	3:6	In Situ Generating CaCO3 Nanoparticles Reinforced Nonflammable Calcium Alginate Biocomposite Fiber.					
36200299	2	69	theme	mechanical	398:407	arg1	performance					409:419	its limited mechanical performance	386:419	its limited mechanical performance	386:419	A natural polysaccharide, calcium alginate, is an intrinsic fire-resistant biodegradable material, but its limited mechanical performance prevents it from being a practical flame-retardant fabric.					
35830836	0	0	theme	cellulose	71:79	arg1	nanocrystals					81:92	cellulose nanocrystals	71:92	cellulose nanocrystals	71:92	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	1	1	theme	food	315:318	arg1	systems					320:326	food systems	315:326	food systems	315:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	6	2	theme	toxicology	931:940	arg1	results					942:948	the toxicology results	927:948	the toxicology results	927:948	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	1	3	from	CNCs	307:310	arg1	systems					320:326	food systems	315:326	food systems	315:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	2	4	theme	CNC-based	471:479	arg1	emulsions					481:489	CNC-based emulsions	471:489	CNC-based emulsions with different oil types	471:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	5	5	theme	lipid	847:851	arg1	digestion					853:861	lipid digestion	847:861	lipid digestion in emulsions with high unsaturation triglycerides	847:911	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	4	6	from	CNCs	664:667	arg1	model					690:694	the high-fat food model	672:694	the high-fat food model	672:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	2	7	theme	different	496:504	arg1	types					510:514	different oil types	496:514	different oil types	496:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	5	8	with	emulsions	866:874	arg1	triglycerides					899:911	high unsaturation triglycerides	881:911	high unsaturation triglycerides	881:911	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	0	9	from	Effects	0:6	arg1	digestion					58:66	the digestion	54:66	the digestion of cellulose nanocrystals in simulated gastrointestinal tract	54:128	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	4	10	theme	acids	733:737	arg1	hydrolysis					708:717	the hydrolysis	704:717	the hydrolysis of free fatty acids (FFAs) from triglycerides	704:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	6	11	theme	cell-layer	1075:1084	arg1	integrity					1086:1094	cell-layer integrity	1075:1094	cell-layer integrity	1075:1094	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	1	12	theme	lipid	245:249	arg1	digestion					251:259	lipid digestion	245:259	lipid digestion	245:259	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	0	13	theme	nanocrystals	81:92	arg1	digestion					58:66	the digestion	54:66	the digestion of cellulose nanocrystals in simulated gastrointestinal tract	54:128	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	1	14	from	toxicity	295:302	arg1	systems					320:326	food systems	315:326	food systems	315:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	3	15	theme	small	528:532	arg1	model					555:559	a small intestine epithelial model	526:559	a small intestine epithelial model	526:559	Finally, a small intestine epithelial model was used to evaluate the influence of cytotoxicity.					
35830836	6	16	theme	0.6 wt	963:968	arg1	CNCs					971:974	0.6 wt% CNCs	963:974	0.6 wt% CNCs	963:974	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	0	17	theme	gastrointestinal	107:122	arg1	tract					124:128	simulated gastrointestinal tract	97:128	simulated gastrointestinal tract	97:128	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	4	18	theme	intestine	790:798	arg1	phase					800:804	the small intestine phase	780:804	the small intestine phase	780:804	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	2	19	with	emulsions	481:489	arg1	types					510:514	different oil types	496:514	different oil types	496:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	2	20	theme	CNCs	356:359	arg1	ability					345:351	the ability	341:351	the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system	341:426	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	0	21	theme	simulated	97:105	arg1	tract					124:128	simulated gastrointestinal tract	97:128	simulated gastrointestinal tract	97:128	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	1	22	from	systems	320:326	arg1	toxicity					295:302	the in vitro gastrointestinal toxicity	265:302	the in vitro gastrointestinal toxicity of CNCs in food systems	265:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	1	22	from	systems	320:326	arg1	digestion					251:259	lipid digestion	245:259	lipid digestion	245:259	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	6	23	contain	had	976:978	arg2	effect					994:999	a slight effect	985:999	a slight effect on reactive oxygen species and cytotoxicity	985:1043	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	23	contain	had	976:978	arg2	change					1065:1070	no significant change	1050:1070	no significant change in cell-layer integrity	1050:1094	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	23	contain	had	976:978	arg1	CNCs					971:974	0.6 wt% CNCs	963:974	0.6 wt% CNCs	963:974	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	4	24	from	addition	644:651	arg1	model					690:694	the high-fat food model	672:694	the high-fat food model	672:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	2	25	theme	oil	506:508	arg1	types					510:514	different oil types	496:514	different oil types	496:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	5	26	theme	high	881:884	arg1	triglycerides					899:911	high unsaturation triglycerides	881:911	high unsaturation triglycerides	881:911	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	6	27	theme	reactive	1004:1011	arg1	species					1020:1026	reactive oxygen species	1004:1026	reactive oxygen species	1004:1026	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	1	28	theme	different	176:184	arg1	types					190:194	different oil types	176:194	different oil types	176:194	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	4	29	from	hydrolysis	708:717	arg1	triglycerides					751:763	triglycerides	751:763	triglycerides	751:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	5	30	theme	unsaturation	886:897	arg1	triglycerides					899:911	high unsaturation triglycerides	881:911	high unsaturation triglycerides	881:911	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	1	31	theme	oil	186:188	arg1	types					190:194	different oil types	176:194	different oil types	176:194	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	0	32	theme	type	17:20	arg1	Effects					0:6	Effects	0:6	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.	0:129	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	5	33	from	digestion	853:861	arg1	emulsions					866:874	emulsions	866:874	emulsions with high unsaturation triglycerides	866:911	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	3	34	theme	intestine	534:542	arg1	model					555:559	a small intestine epithelial model	526:559	a small intestine epithelial model	526:559	Finally, a small intestine epithelial model was used to evaluate the influence of cytotoxicity.					
35830836	6	35	theme	oxygen	1013:1018	arg1	species					1020:1026	reactive oxygen species	1004:1026	reactive oxygen species	1004:1026	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	1	36	theme	types	190:194	arg1	impact					166:171	the impact	162:171	the impact of different oil types on the cellulose nanocrystals (CNCs)	162:231	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	0	37	theme	lipid	11:15	arg1	type					17:20	lipid type	11:20	lipid type	11:20	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	1	38	theme	in	269:270	arg1	toxicity					295:302	the in vitro gastrointestinal toxicity	265:302	the in vitro gastrointestinal toxicity of CNCs in food systems	265:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	1	39	from	digestion	251:259	arg1	systems					320:326	food systems	315:326	food systems	315:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	3	40	theme	epithelial	544:553	arg1	model					555:559	a small intestine epithelial model	526:559	a small intestine epithelial model	526:559	Finally, a small intestine epithelial model was used to evaluate the influence of cytotoxicity.					
35830836	6	41	theme	slight	987:992	arg1	effect					994:999	a slight effect	985:999	a slight effect on reactive oxygen species and cytotoxicity	985:1043	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	0	42	theme	toxicological	26:38	arg1	properties					40:49	toxicological properties	26:49	toxicological properties	26:49	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	4	43	theme	0.6 wt	656:661	arg1	CNCs					664:667	0.6 wt% CNCs	656:667	0.6 wt% CNCs in the high-fat food model	656:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	5	44	theme	best	823:826	arg1	effect					828:833	the best effect	819:833	the best effect	819:833	CNCs showed the best effect in reducing lipid digestion in emulsions with high unsaturation triglycerides.					
35830836	2	45	theme	gastrointestinal	446:461	arg1	fate					463:466	the gastrointestinal fate	442:466	the gastrointestinal fate of CNC-based emulsions with different oil types	442:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	1	46	theme	gastrointestinal	278:293	arg1	toxicity					295:302	the in vitro gastrointestinal toxicity	265:302	the in vitro gastrointestinal toxicity of CNCs in food systems	265:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	0	47	from	digestion	58:66	arg1	tract					124:128	simulated gastrointestinal tract	97:128	simulated gastrointestinal tract	97:128	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	2	48	theme	gastrointestinal	404:419	arg1	system					421:426	a simulated gastrointestinal system	392:426	a simulated gastrointestinal system	392:426	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	1	49	theme	cellulose	203:211	arg1	CNCs					227:230	CNCs	227:230	CNCs	227:230	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	1	49	theme	cellulose	203:211	arg1	nanocrystals					213:224	the cellulose nanocrystals	199:224	the cellulose nanocrystals (CNCs)	199:231	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	4	50	theme	fatty	727:731	arg1	acids					733:737	free fatty acids	722:737	free fatty acids (FFAs) from triglycerides	722:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	50	theme	fatty	727:731	arg1	FFAs					740:743	FFAs	740:743	FFAs	740:743	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	51	theme	food	685:688	arg1	model					690:694	the high-fat food model	672:694	the high-fat food model	672:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	0	52	theme	properties	40:49	arg1	Effects					0:6	Effects	0:6	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.	0:129	Effects of lipid type and toxicological properties on the digestion of cellulose nanocrystals in simulated gastrointestinal tract.					
35830836	4	53	theme	small	784:788	arg1	intestine					790:798	the small intestine	780:798	the small intestine phase	780:804	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	6	54	from	effect	994:999	arg1	cytotoxicity					1032:1043	cytotoxicity	1032:1043	cytotoxicity	1032:1043	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	54	from	effect	994:999	arg1	integrity					1086:1094	cell-layer integrity	1075:1094	cell-layer integrity	1075:1094	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	54	from	effect	994:999	arg1	species					1020:1026	reactive oxygen species	1004:1026	reactive oxygen species	1004:1026	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	3	55	used	used	565:568	arg2	model					555:559	a small intestine epithelial model	526:559	a small intestine epithelial model	526:559	Finally, a small intestine epithelial model was used to evaluate the influence of cytotoxicity.					
35830836	1	56	theme	CNCs	307:310	arg1	toxicity					295:302	the in vitro gastrointestinal toxicity	265:302	the in vitro gastrointestinal toxicity of CNCs in food systems	265:326	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	1	56	theme	CNCs	307:310	arg1	digestion					251:259	lipid digestion	245:259	lipid digestion	245:259	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	3	57	theme	cytotoxicity	599:610	arg1	influence					586:594	the influence	582:594	the influence of cytotoxicity	582:610	Finally, a small intestine epithelial model was used to evaluate the influence of cytotoxicity.					
35830836	6	58	from	change	1065:1070	arg1	cytotoxicity					1032:1043	cytotoxicity	1032:1043	cytotoxicity	1032:1043	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	58	from	change	1065:1070	arg1	integrity					1086:1094	cell-layer integrity	1075:1094	cell-layer integrity	1075:1094	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	58	from	change	1065:1070	arg1	species					1020:1026	reactive oxygen species	1004:1026	reactive oxygen species	1004:1026	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	6	59	theme	significant	1053:1063	arg1	change					1065:1070	no significant change	1050:1070	no significant change in cell-layer integrity	1050:1094	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	4	60	theme	free	722:725	arg1	acids					733:737	free fatty acids	722:737	free fatty acids (FFAs) from triglycerides	722:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	60	theme	free	722:725	arg1	FFAs					740:743	FFAs	740:743	FFAs	740:743	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	2	61	theme	lipid	373:377	arg1	digestion					379:387	lipid digestion	373:387	lipid digestion	373:387	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	4	62	from	triglycerides	751:763	arg1	acids					733:737	free fatty acids	722:737	free fatty acids (FFAs) from triglycerides	722:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	62	from	triglycerides	751:763	arg1	hydrolysis					708:717	the hydrolysis	704:717	the hydrolysis of free fatty acids (FFAs) from triglycerides	704:763	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	62	from	triglycerides	751:763	arg1	FFAs					740:743	FFAs	740:743	FFAs	740:743	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	63	theme	CNCs	664:667	arg1	addition					644:651	the addition	640:651	the addition of 0.6 wt% CNCs in the high-fat food model	640:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	64	from	model	690:694	arg1	addition					644:651	the addition	640:651	the addition of 0.6 wt% CNCs in the high-fat food model	640:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	6	65	theme	%	969:969	arg1	CNCs					971:974	0.6 wt% CNCs	963:974	0.6 wt% CNCs	963:974	In addition, the toxicology results suggest that 0.6 wt% CNCs had only a slight effect on reactive oxygen species and cytotoxicity, and no significant change in cell-layer integrity.					
35830836	2	66	theme	emulsions	481:489	arg1	fate					463:466	the gastrointestinal fate	442:466	the gastrointestinal fate of CNC-based emulsions with different oil types	442:514	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	1	67	dep	in	269:270	arg1	vitro					272:276	vitro	272:276	vitro	272:276	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	2	68	theme	simulated	394:402	arg1	system					421:426	a simulated gastrointestinal system	392:426	a simulated gastrointestinal system	392:426	We explored the ability of CNCs to modulate lipid digestion in a simulated gastrointestinal system and monitored the gastrointestinal fate of CNC-based emulsions with different oil types.					
35830836	1	69	from	impact	166:171	arg1	CNCs					227:230	CNCs	227:230	CNCs	227:230	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	1	69	from	impact	166:171	arg1	nanocrystals					213:224	the cellulose nanocrystals	199:224	the cellulose nanocrystals (CNCs)	199:231	This study aimed to understand the impact of different oil types on the cellulose nanocrystals (CNCs) to modulate lipid digestion and the in vitro gastrointestinal toxicity of CNCs in food systems.					
35830836	4	70	theme	%	662:662	arg1	CNCs					664:667	0.6 wt% CNCs	656:667	0.6 wt% CNCs in the high-fat food model	656:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
35830836	4	71	theme	high-fat	676:683	arg1	model					690:694	the high-fat food model	672:694	the high-fat food model	672:694	The results suggested that the addition of 0.6 wt% CNCs in the high-fat food model reduced the hydrolysis of free fatty acids (FFAs) from triglycerides by 37.8% after the small intestine phase.					
37321743	2	0	theme	ice-induced	413:423	arg1	assembly					425:432	ice-induced assembly	413:432	ice-induced assembly	413:432	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	7	1	theme	rapid	1018:1022	arg1	reduction					1046:1054	the rapid electrical resistance reduction	1014:1054	the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time	1014:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	1	theme	rapid	1018:1022	arg1	less					1154:1157	less	1154:1157	less	1154:1157	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	5	2	theme	MXene	797:801	arg1	synergism					775:783	the synergism	771:783	the synergism of PMSQ and MXene, PCM	771:806	In addition, benefiting from the synergism of PMSQ and MXene, PCM displayed good flame retardancy and improved thermostability.					
37321743	7	3	theme	electrical	1024:1033	arg1	reduction					1046:1054	the rapid electrical resistance reduction	1014:1054	the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time	1014:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	3	theme	electrical	1024:1033	arg1	less					1154:1157	less	1154:1157	less	1154:1157	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	1	4	theme	Multifunctional	71:85	arg1	aerogels					101:108	Multifunctional biomass-based aerogels	71:108	Multifunctional biomass-based aerogels with mechanically robust and high fire safety	71:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	3	5	theme	own	618:620	arg1	weight					622:627	its own weight	614:627	its own weight	614:627	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	5	6	from	synergism	775:783	arg1	benefiting					755:764	benefiting	755:764	benefiting from the synergism of PMSQ and MXene, PCM	755:806	In addition, benefiting from the synergism of PMSQ and MXene, PCM displayed good flame retardancy and improved thermostability.					
37321743	3	7	theme	weight	622:627	arg1	times					605:609	9000 times	600:609	9000 times of its own weight	600:627	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	6	8	theme	oxygen	883:888	arg1	higher					907:912	higher	907:912	higher	907:912	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	6	8	theme	oxygen	883:888	arg1	index					890:894	The limiting oxygen index	870:894	The limiting oxygen index of PCM	870:901	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	1	9	theme	biomass-based	87:99	arg1	aerogels					101:108	Multifunctional biomass-based aerogels	71:108	Multifunctional biomass-based aerogels with mechanically robust and high fire safety	71:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	7	10	with	endowed	1085:1091	arg1	capability					1125:1134	sensitive fire-warning capability	1102:1134	sensitive fire-warning capability	1102:1134	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	8	11	theme	aerogels	1358:1365	arg1	application					1292:1302	application	1292:1302	application	1292:1302	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	8	11	theme	aerogels	1358:1365	arg1	preparation					1276:1286	preparation	1276:1286	preparation	1276:1286	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	6	12	theme	limiting	874:881	arg1	higher					907:912	higher	907:912	higher	907:912	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	6	12	theme	limiting	874:881	arg1	index					890:894	The limiting oxygen index	870:894	The limiting oxygen index of PCM	870:901	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	2	13	theme	composite	331:339	arg1	aerogel					341:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel	275:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance	275:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	13	theme	composite	331:339	arg1	PCM					350:352	PCM	350:352	PCM	350:352	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	0	14	theme	fire	56:59	arg1	fighting					61:68	intelligent fire fighting	44:68	intelligent fire fighting	44:68	Multifunctional cellulose-based aerogel for intelligent fire fighting.					
37321743	8	15	dep	preparation	1276:1286	arg1	the					1272:1274	the	1272:1274	the	1272:1274	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	2	16	theme	/cellulose/MXene	314:329	arg1	aerogel					341:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel	275:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance	275:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	16	theme	/cellulose/MXene	314:329	arg1	PCM					350:352	PCM	350:352	PCM	350:352	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	7	17	dep	temperature	1073:1083	arg1	endowed					1085:1091	endowed	1085:1091	endowed	1085:1091	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	17	dep	temperature	1073:1083	arg1	time					1145:1148	trigger time	1137:1148	high temperature endowed PCM with sensitive fire-warning capability (trigger time	1068:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	1	18	theme	environmentally-friendly	199:222	arg1	fire					236:239	environmentally-friendly intelligent fire	199:239	environmentally-friendly intelligent fire fighting but challenging	199:264	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	2	19	theme	superior	360:367	arg1	performance					383:393	superior comprehensive performance	360:393	superior comprehensive performance	360:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	1	20	theme	intelligent	224:234	arg1	fire					236:239	environmentally-friendly intelligent fire	199:239	environmentally-friendly intelligent fire fighting but challenging	199:264	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	7	21	dep	people	1205:1210	arg1	evacuate					1215:1222	evacuate	1215:1222	to evacuate	1212:1222	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	1	22	theme	robust	128:133	arg1	safety					149:154	mechanically robust and high fire safety	115:154	mechanically robust and high fire safety	115:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	2	23	theme	in-situ	438:444	arg1	mineralization					446:459	in-situ mineralization	438:459	in-situ mineralization	438:459	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	7	24	theme	trigger	1137:1143	arg1	time					1145:1148	trigger time	1137:1148	high temperature endowed PCM with sensitive fire-warning capability (trigger time	1068:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	8	25	theme	next-generation	1311:1325	arg1	aerogels					1358:1365	the next-generation high performance biomass-based aerogels	1307:1365	the next-generation high performance biomass-based aerogels	1307:1365	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	1	26	theme	high	139:142	arg1	safety					149:154	mechanically robust and high fire safety	115:154	mechanically robust and high fire safety	115:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	1	27	with	aerogels	101:108	arg1	safety					149:154	mechanically robust and high fire safety	115:154	mechanically robust and high fire safety	115:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	5	28	theme	PMSQ	788:791	arg1	synergism					775:783	the synergism	771:783	the synergism of PMSQ and MXene, PCM	771:806	In addition, benefiting from the synergism of PMSQ and MXene, PCM displayed good flame retardancy and improved thermostability.					
37321743	4	29	theme	piezoresistive	718:731	arg1	sensing					733:739	sensitive piezoresistive sensing	708:739	sensitive piezoresistive sensing	708:739	Moreover, PCM demonstrated outstanding thermal insulation, hydrophobicity and sensitive piezoresistive sensing.					
37321743	2	30	theme	novel	277:281	arg1	aerogel					341:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel	275:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance	275:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	30	theme	novel	277:281	arg1	PCM					350:352	PCM	350:352	PCM	350:352	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	1	31	theme	fire	236:239	arg1	development					184:194	the development	180:194	the development of environmentally-friendly intelligent fire fighting but challenging	180:264	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	3	32	theme	mechanical	514:523	arg1	resilience					525:534	excellent mechanical resilience	504:534	excellent mechanical resilience	504:534	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	3	32	theme	mechanical	514:523	arg1	weight					481:486	light weight	475:486	light weight (16.2 mg·cm-3)	475:501	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	0	33	theme	intelligent	44:54	arg1	fighting					61:68	intelligent fire fighting	44:68	intelligent fire fighting	44:68	Multifunctional cellulose-based aerogel for intelligent fire fighting.					
37321743	8	34	theme	new	1255:1257	arg1	insights					1259:1266	new insights	1255:1266	new insights for the preparation and application of the next-generation high performance biomass-based aerogels	1255:1365	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	8	35	theme	performance	1332:1342	arg1	aerogels					1358:1365	the next-generation high performance biomass-based aerogels	1307:1365	the next-generation high performance biomass-based aerogels	1307:1365	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	1	36	dep	fire	236:239	arg1	challenging					254:264	challenging	254:264	challenging	254:264	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	1	36	dep	fire	236:239	arg1	fighting					241:248	fighting	241:248	fighting	241:248	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	4	37	theme	sensitive	708:716	arg1	sensing					733:739	sensitive piezoresistive sensing	708:739	sensitive piezoresistive sensing	708:739	Moreover, PCM demonstrated outstanding thermal insulation, hydrophobicity and sensitive piezoresistive sensing.					
37321743	7	38	theme	valuable	1187:1194	arg1	time					1196:1199	valuable time	1187:1199	valuable time for people to evacuate and relief	1187:1233	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	39	theme	sensitive	1102:1110	arg1	capability					1125:1134	sensitive fire-warning capability	1102:1134	sensitive fire-warning capability	1102:1134	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	1	40	theme	fire	144:147	arg1	safety					149:154	mechanically robust and high fire safety	115:154	mechanically robust and high fire safety	115:154	Multifunctional biomass-based aerogels with mechanically robust and high fire safety are urgently needed for the development of environmentally-friendly intelligent fire fighting but challenging.					
37321743	3	41	theme	light	475:479	arg1	resilience					525:534	excellent mechanical resilience	504:534	excellent mechanical resilience	504:534	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	3	41	theme	light	475:479	arg1	16.2 mg·cm-3					489:500	16.2 mg·cm-3	489:500	16.2 mg·cm-3	489:500	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	3	41	theme	light	475:479	arg1	weight					481:486	light weight	475:486	light weight (16.2 mg·cm-3)	475:501	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	7	42	theme	fire-warning	1112:1123	arg1	capability					1125:1134	sensitive fire-warning capability	1102:1134	sensitive fire-warning capability	1102:1134	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	43	from	temperature	1073:1083	arg1	reduction					1046:1054	the rapid electrical resistance reduction	1014:1054	the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time	1014:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	43	from	temperature	1073:1083	arg1	less					1154:1157	less	1154:1157	less	1154:1157	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	8	44	theme	biomass-based	1344:1356	arg1	aerogels					1358:1365	the next-generation high performance biomass-based aerogels	1307:1365	the next-generation high performance biomass-based aerogels	1307:1365	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	7	45	theme	high	1068:1071	arg1	temperature					1073:1083	high temperature	1068:1083	high temperature endowed PCM with sensitive fire-warning capability (trigger time	1068:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	4	46	theme	thermal	669:675	arg1	insulation					677:686	outstanding thermal insulation	657:686	outstanding thermal insulation	657:686	Moreover, PCM demonstrated outstanding thermal insulation, hydrophobicity and sensitive piezoresistive sensing.					
37321743	2	47	theme	PMSQ	309:312	arg1	aerogel					341:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel	275:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance	275:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	47	theme	PMSQ	309:312	arg1	PCM					350:352	PCM	350:352	PCM	350:352	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	48	theme	comprehensive	369:381	arg1	performance					383:393	superior comprehensive performance	360:393	superior comprehensive performance	360:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	4	49	theme	outstanding	657:667	arg1	insulation					677:686	outstanding thermal insulation	657:686	outstanding thermal insulation	657:686	Moreover, PCM demonstrated outstanding thermal insulation, hydrophobicity and sensitive piezoresistive sensing.					
37321743	5	50	theme	good	818:821	arg1	retardancy					829:838	good flame retardancy	818:838	good flame retardancy	818:838	In addition, benefiting from the synergism of PMSQ and MXene, PCM displayed good flame retardancy and improved thermostability.					
37321743	6	51	theme	PCM	899:901	arg1	higher					907:912	higher	907:912	higher	907:912	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	6	51	theme	PCM	899:901	arg1	index					890:894	The limiting oxygen index	870:894	The limiting oxygen index of PCM	870:901	The limiting oxygen index of PCM was higher than 45.0 %, and it quickly self-extinguished after being removed away from fire.					
37321743	8	52	theme	high	1327:1330	arg1	aerogels					1358:1365	the next-generation high performance biomass-based aerogels	1307:1365	the next-generation high performance biomass-based aerogels	1307:1365	This work provides new insights for the preparation and application of the next-generation high performance biomass-based aerogels.					
37321743	7	53	theme	MXene	1059:1063	arg1	reduction					1046:1054	the rapid electrical resistance reduction	1014:1054	the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time	1014:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	53	theme	MXene	1059:1063	arg1	less					1154:1157	less	1154:1157	less	1154:1157	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	3	54	theme	excellent	504:512	arg1	resilience					525:534	excellent mechanical resilience	504:534	excellent mechanical resilience	504:534	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	3	54	theme	excellent	504:512	arg1	weight					481:486	light weight	475:486	light weight (16.2 mg·cm-3)	475:501	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	5	55	theme	flame	823:827	arg1	retardancy					829:838	good flame retardancy	818:838	good flame retardancy	818:838	In addition, benefiting from the synergism of PMSQ and MXene, PCM displayed good flame retardancy and improved thermostability.					
37321743	3	56	theme	times	605:609	arg1	pressure					588:595	the pressure	584:595	the pressure of 9000 times of its own weight	584:627	It exhibited light weight (16.2 mg·cm-3), excellent mechanical resilience, and rapidly recovered after being subjected to the pressure of 9000 times of its own weight.					
37321743	2	57	theme	polymethylsilsesquioxane	283:306	arg1	aerogel					341:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel	275:347	a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance	275:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	2	57	theme	polymethylsilsesquioxane	283:306	arg1	PCM					350:352	PCM	350:352	PCM	350:352	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
37321743	7	58	theme	resistance	1035:1044	arg1	reduction					1046:1054	the rapid electrical resistance reduction	1014:1054	the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time	1014:1148	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	7	58	theme	resistance	1035:1044	arg1	less					1154:1157	less	1154:1157	less	1154:1157	More importantly, the rapid electrical resistance reduction of MXene at high temperature endowed PCM with sensitive fire-warning capability (trigger time was less than 1.8 s), which provided valuable time for people to evacuate and relief.					
37321743	2	59	with	aerogel	341:347	arg1	performance					383:393	superior comprehensive performance	360:393	superior comprehensive performance	360:393	Herein, a novel polymethylsilsesquioxane (PMSQ)/cellulose/MXene composite aerogel (PCM) with superior comprehensive performance was fabricated by ice-induced assembly and in-situ mineralization.					
36652424	5	0	theme	molecular	600:608	arg1	techniques					610:619	molecular techniques	600:619	molecular techniques	600:619	Cultivation and molecular techniques were used to characterize the fungi inhabiting the documents.					
36652424	8	1	theme	fungal	1059:1064	arg1	colonization					1066:1077	fungal colonization	1059:1077	fungal colonization	1059:1077	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	5	2	dep	the	668:670	arg1	documents					672:680	documents	672:680	documents	672:680	Cultivation and molecular techniques were used to characterize the fungi inhabiting the documents.					
36652424	8	3	theme	cotton-based	1015:1026	arg1	paper					1028:1032	cotton-based paper	1015:1032	cotton-based paper	1015:1032	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	8	3	theme	cotton-based	1015:1026	arg1	resistant					1046:1054	resistant	1046:1054	resistant	1046:1054	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	9	4	dep	invaluable	1358:1367	arg1	documents					1369:1377	documents	1369:1377	documents	1369:1377	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	2	5	used	used	260:263	arg2	We					257:258	We	257:258	We	257:258	We used nondestructive techniques (i.e., ATR-FTIR and XRF) to determine paper and ink composition.					
36652424	1	6	theme	Rica	241:244	arg1	Independence					215:226	the Independence Act	211:230	the Independence Act of Costa Rica from 1821	211:254	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	5	7	used	used	626:629	arg2	techniques					610:619	molecular techniques	600:619	molecular techniques	600:619	Cultivation and molecular techniques were used to characterize the fungi inhabiting the documents.					
36652424	5	7	used	used	626:629	arg2	Cultivation					584:594	Cultivation	584:594	Cultivation	584:594	Cultivation and molecular techniques were used to characterize the fungi inhabiting the documents.					
36652424	9	8	theme	paper	1254:1258	arg1	composition					1260:1270	paper composition	1254:1270	paper composition	1254:1270	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	7	9	theme	cellulolytic	907:918	arg1	activity					920:927	cellulolytic activity	907:927	cellulolytic activity correlated to their ability to cause deterioration of the paper	907:991	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	2	10	theme	nondestructive	265:278	arg1	techniques					280:289	nondestructive techniques	265:289	nondestructive techniques (i.e., ATR-FTIR and XRF)	265:314	We used nondestructive techniques (i.e., ATR-FTIR and XRF) to determine paper and ink composition.					
36652424	9	11	with	relationship	1236:1247	arg1	composition					1260:1270	paper composition	1254:1270	paper composition	1254:1270	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	0	12	theme	Rica	75:78	arg1	historic					47:54	historic	47:54	historic	47:54	Fungi with history: Unveiling the mycobiota of historic documents of Costa Rica.					
36652424	9	13	dep	historic	1209:1216	arg1	documents					1218:1226	documents	1218:1226	documents	1218:1226	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	8	14	theme	cellulolytic	1114:1125	arg1	activity					1127:1134	cellulolytic activity	1114:1134	cellulolytic activity	1114:1134	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	7	15	theme	fungi	891:895	arg1	%					882:882	95%	880:882	95% of the fungi	880:895	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	7	15	theme	fungi	891:895	arg1	fungi					891:895	the fungi	887:895	the fungi	887:895	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	3	16	theme	lignin	486:491	arg1	content					493:499	an increased lignin content	473:499	an increased lignin content	473:499	Results show that some documents are composed of cotton-based paper, whereas others were made of wood cellulose with an increased lignin content.					
36652424	3	17	theme	cotton-based	405:416	arg1	paper					418:422	cotton-based paper	405:422	cotton-based paper	405:422	Results show that some documents are composed of cotton-based paper, whereas others were made of wood cellulose with an increased lignin content.					
36652424	9	18	theme	valuable	1285:1292	arg1	information					1294:1304	valuable information	1285:1304	valuable information to develop strategies to conserve and restore these invaluable documents	1285:1377	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	3	19	dep	some	374:377	arg1	documents					379:387	documents	379:387	documents	379:387	Results show that some documents are composed of cotton-based paper, whereas others were made of wood cellulose with an increased lignin content.					
36652424	9	20	with	historic	1209:1216	arg1	composition					1260:1270	paper composition	1254:1270	paper composition	1254:1270	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	2	21	dep	ATR-FTIR	298:305	arg1	i.e.					292:295	i.e.	292:295	i.e.	292:295	We used nondestructive techniques (i.e., ATR-FTIR and XRF) to determine paper and ink composition.					
36652424	2	22	theme	ink	339:341	arg1	composition					343:353	ink composition	339:353	ink composition	339:353	We used nondestructive techniques (i.e., ATR-FTIR and XRF) to determine paper and ink composition.					
36652424	6	23	dep	wood-cellulose-based	739:758	arg1	documents					760:768	documents	760:768	documents	760:768	In total, 22 fungal isolates were obtained: 15 from the wood-cellulose-based documents and seven from the other three cotton-based.					
36652424	9	24	theme	fungal	1178:1183	arg1	diversity					1185:1193	the fungal diversity	1174:1193	the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents	1174:1377	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	1	25	from	1821	251:254	arg1	Independence					215:226	the Independence Act	211:230	the Independence Act of Costa Rica from 1821	211:254	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	0	26	dep	historic	47:54	arg1	documents					56:64	documents	56:64	documents	56:64	Fungi with history: Unveiling the mycobiota of historic documents of Costa Rica.					
36652424	3	27	theme	wood	453:456	arg1	cellulose					458:466	wood cellulose	453:466	wood cellulose	453:466	Results show that some documents are composed of cotton-based paper, whereas others were made of wood cellulose with an increased lignin content.					
36652424	6	28	dep	obtained	717:724	arg1	15					727:728	15	727:728	15	727:728	In total, 22 fungal isolates were obtained: 15 from the wood-cellulose-based documents and seven from the other three cotton-based.					
36652424	6	28	dep	obtained	717:724	arg1	seven					774:778	seven	774:778	seven	774:778	In total, 22 fungal isolates were obtained: 15 from the wood-cellulose-based documents and seven from the other three cotton-based.					
36652424	9	29	theme	diversity	1185:1193	arg1	knowledge					1161:1169	the knowledge	1157:1169	the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents	1157:1377	This work increases the knowledge of the fungal diversity that inhabits historic documents and its relationship with paper composition and provides valuable information to develop strategies to conserve and restore these invaluable documents.					
36652424	7	30	theme	paper	987:991	arg1	deterioration					966:978	deterioration	966:978	deterioration of the paper	966:991	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	1	31	dep	Independence	215:226	arg1	Act					228:230	Act	228:230	Act	228:230	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	1	32	dep	historic	165:172	arg1	documents					174:182	documents	174:182	documents	174:182	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	1	33	theme	physicochemical	96:110	arg1	characteristics					112:126	physicochemical characteristics	96:126	physicochemical characteristics	96:126	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	1	33	theme	physicochemical	96:110	arg1	Independence					215:226	the Independence Act	211:230	the Independence Act of Costa Rica from 1821	211:254	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	7	34	theme	recovered	863:871	arg1	fungi					873:877	the recovered fungi	859:877	the recovered fungi	859:877	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	1	35	from	Rica	195:198	arg1	historic					165:172	historic	165:172	historic	165:172	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	7	36	theme	fungi	873:877	arg1	activity					847:854	the cellulolytic activity	830:854	the cellulolytic activity of the recovered fungi	830:877	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
36652424	6	37	theme	fungal	696:701	arg1	isolates					703:710	22 fungal isolates	693:710	22 fungal isolates	693:710	In total, 22 fungal isolates were obtained: 15 from the wood-cellulose-based documents and seven from the other three cotton-based.					
36652424	4	38	dep	the	554:556	arg1	documents					558:566	documents	558:566	documents	558:566	We also determined that the ink employed in some of the documents is ferrogallic.					
36652424	1	39	dep	characteristics	112:126	arg1	the					92:94	the	92:94	the	92:94	We studied the physicochemical characteristics and mycobiota associated to five key historic documents from Costa Rica, including the Independence Act of Costa Rica from 1821.					
36652424	0	40	theme	historic	47:54	arg1	mycobiota					34:42	the mycobiota	30:42	the mycobiota of historic documents of Costa Rica	30:78	Fungi with history: Unveiling the mycobiota of historic documents of Costa Rica.					
36652424	8	41	contain	have	1109:1112	arg1	most					1088:1091	most	1088:1091	most	1088:1091	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	8	41	contain	have	1109:1112	arg2	activity					1127:1134	cellulolytic activity	1114:1134	cellulolytic activity	1114:1134	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	8	41	contain	have	1109:1112	arg1	isolates					1100:1107	the isolates	1096:1107	the isolates	1096:1107	Results suggest that cotton-based paper is the most resistant to fungal colonization and that most of the isolates have cellulolytic activity.					
36652424	0	42	dep	Fungi	0:4	arg1	history					11:17	history	11:17	history	11:17	Fungi with history: Unveiling the mycobiota of historic documents of Costa Rica.					
36652424	3	43	theme	increased	476:484	arg1	content					493:499	an increased lignin content	473:499	an increased lignin content	473:499	Results show that some documents are composed of cotton-based paper, whereas others were made of wood cellulose with an increased lignin content.					
36652424	7	44	theme	cellulolytic	834:845	arg1	activity					847:854	the cellulolytic activity	830:854	the cellulolytic activity of the recovered fungi	830:877	We also tested the cellulolytic activity of the recovered fungi; 95% of the fungi presented cellulolytic activity correlated to their ability to cause deterioration of the paper.					
35487262	6	0	from	exterior	1062:1069	arg1	partition					1007:1015	that partition	1002:1015	that partition of dissolved drug molecules from the aqueous exterior into the membrane	1002:1087	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	6	0	from	exterior	1062:1069	arg1	molecules					1035:1043	dissolved drug molecules	1020:1043	dissolved drug molecules from the aqueous exterior	1020:1069	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	5	1	theme	molecules	943:951	arg1	ability					916:922	ability	916:922	ability	916:922	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	5	1	theme	molecules	943:951	arg1	mobility					903:910	molecular mobility	893:910	molecular mobility	893:910	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	4	2	theme	artificial	556:565	arg1	PermeaPad®					580:589	PermeaPad®	580:589	PermeaPad®	580:589	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	4	2	theme	artificial	556:565	arg1	biomembrane					567:577	An artificial biomembrane	553:577	An artificial biomembrane (PermeaPad®)	553:590	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	7	3	theme	other	1163:1167	arg1	words					1169:1173	other words	1163:1173	other words	1163:1173	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	2	4	theme	lipophilic	391:400	arg1	membranes					402:410	lipophilic membranes	391:410	lipophilic membranes	391:410	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	7	5	theme	lipophilic	1235:1244	arg1	membranes					1246:1254	lipophilic membranes	1235:1254	lipophilic membranes	1235:1254	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	4	6	theme	donor	624:628	arg1	composition					637:647	donor medium composition	624:647	donor medium composition	624:647	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	4	7	used	used	596:599	arg2	biomembrane					567:577	An artificial biomembrane	553:577	An artificial biomembrane (PermeaPad®)	553:590	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	4	7	used	used	596:599	arg2	PermeaPad®					580:589	PermeaPad®	580:589	PermeaPad®	580:589	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	8	8	theme	drug	1379:1382	arg1	concentration					1384:1396	the drug concentration	1375:1396	the drug concentration	1375:1396	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	5	9	theme	lipophilic	975:984	arg1	membrane					986:993	the lipophilic membrane	971:993	the lipophilic membrane	971:993	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	4	10	from	effect	614:619	arg1	permeation					657:666	drug permeation	652:666	drug permeation	652:666	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	7	11	theme	dissolved	1324:1332	arg1	drug					1334:1337	dissolved drug	1324:1337	dissolved drug	1324:1337	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	8	12	theme	thermodynamic	1402:1414	arg1	activity					1416:1423	thermodynamic activity	1402:1423	thermodynamic activity of the dissolved drug molecules	1402:1455	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	1	13	theme	water-soluble	199:211	arg1	complexes					231:239	water-soluble drug/cyclodextrin complexes	199:239	water-soluble drug/cyclodextrin complexes	199:239	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	6	14	theme	drug	1030:1033	arg1	molecules					1035:1043	dissolved drug molecules	1020:1043	dissolved drug molecules from the aqueous exterior	1020:1069	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	1	15	theme	hydrophilic	92:102	arg1	Cyclodextrins					74:86	Cyclodextrins	74:86	Cyclodextrins	74:86	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	1	15	theme	hydrophilic	92:102	arg1	oligosaccharides					104:119	hydrophilic oligosaccharides	92:119	hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes	92:239	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	1	16	theme	drug/cyclodextrin	213:229	arg1	complexes					231:239	water-soluble drug/cyclodextrin complexes	199:239	water-soluble drug/cyclodextrin complexes	199:239	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	7	17	theme	aqueous	1196:1202	arg1	solutions					1217:1225	aqueous cyclodextrin solutions	1196:1225	aqueous cyclodextrin solutions	1196:1225	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	5	18	theme	aqueous	693:699	arg1	solutions					701:709	aqueous solutions	693:709	aqueous solutions	693:709	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	1	19	theme	complexes	231:239	arg1	formation					186:194	formation	186:194	formation of water-soluble drug/cyclodextrin complexes	186:239	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	7	20	theme	cyclodextrin	1204:1215	arg1	solutions					1217:1225	aqueous cyclodextrin solutions	1196:1225	aqueous cyclodextrin solutions	1196:1225	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	6	21	theme	dissolved	1020:1028	arg1	molecules					1035:1043	dissolved drug molecules	1020:1043	dissolved drug molecules from the aqueous exterior	1020:1069	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	2	22	theme	drug	424:427	arg1	bioavailability					429:443	drug bioavailability	424:443	drug bioavailability	424:443	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	0	23	theme	Membrane	23:30	arg1	Permeation					32:41	Drug Membrane Permeation	18:41	Drug Membrane Permeation	18:41	Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations.					
35487262	6	24	from	partition	1007:1015	arg1	exterior					1062:1069	the aqueous exterior	1050:1069	the aqueous exterior	1050:1069	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	8	25	theme	dissolved	1432:1440	arg1	molecules					1447:1455	the dissolved drug molecules	1428:1455	the dissolved drug molecules	1428:1455	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	8	26	theme	molecules	1447:1455	arg1	concentration					1384:1396	the drug concentration	1375:1396	the drug concentration	1375:1396	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	8	26	theme	molecules	1447:1455	arg1	activity					1416:1423	thermodynamic activity	1402:1423	thermodynamic activity of the dissolved drug molecules	1402:1455	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	2	27	theme	oral	465:468	arg1	administration					470:483	oral administration	465:483	oral administration	465:483	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	0	28	theme	Drug	18:21	arg1	Permeation					32:41	Drug Membrane Permeation	18:41	Drug Membrane Permeation	18:41	Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations.					
35487262	7	29	from	solutions	1217:1225	arg1	flux					1186:1189	that drug flux	1176:1189	that drug flux from aqueous cyclodextrin solutions through lipophilic membranes	1176:1254	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	7	30	theme	drug	1181:1184	arg1	flux					1186:1189	that drug flux	1176:1189	that drug flux from aqueous cyclodextrin solutions through lipophilic membranes	1176:1254	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	2	31	dep	hydrophilic	269:279	arg1	hydrophilic					269:279	hydrophilic	269:279	hydrophilic	269:279	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	2	31	dep	hydrophilic	269:279	arg1	complexes					255:263	the complexes	251:263	the complexes	251:263	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	2	31	dep	hydrophilic	269:279	arg1	permeate					301:308	permeate	301:308	do not permeate biological membranes	294:329	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	0	32	dep	Considerations	58:71	arg1	Cyclodextrins					0:12	Cyclodextrins	0:12	Cyclodextrins	0:12	Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations.					
35487262	0	32	dep	Considerations	58:71	arg1	Permeation					32:41	Drug Membrane Permeation	18:41	Drug Membrane Permeation	18:41	Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations.					
35487262	6	33	theme	thermodynamic	1118:1130	arg1	activity					1132:1139	their thermodynamic activity	1112:1139	their thermodynamic activity	1112:1139	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	5	34	theme	disperse	757:764	arg1	systems					766:772	disperse systems	757:772	disperse systems but rather like organic cosolvents such as ethanol	757:823	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	5	34	theme	disperse	757:764	arg1	ethanol					817:823	ethanol	817:823	ethanol	817:823	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	8	35	theme	drug	1442:1445	arg1	molecules					1447:1455	the dissolved drug molecules	1428:1455	the dissolved drug molecules	1428:1455	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	5	36	theme	molecular	893:901	arg1	mobility					903:910	molecular mobility	893:910	molecular mobility	893:910	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	8	37	theme	Maximum	1340:1346	arg1	flux					1348:1351	Maximum flux	1340:1351	Maximum flux	1340:1351	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	5	38	theme	lipophilic	927:936	arg1	molecules					943:951	lipophilic drug molecules	927:951	lipophilic drug molecules	927:951	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	5	39	dep	mobility	903:910	arg1	the					889:891	the	889:891	the	889:891	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	1	40	theme	aqueous	139:145	arg1	solubility					147:156	aqueous solubility	139:156	aqueous solubility of lipophilic drugs	139:176	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	0	41	theme	Thermodynamic	44:56	arg1	Considerations					58:71	Thermodynamic Considerations	44:71	Thermodynamic Considerations	44:71	Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations.					
35487262	5	42	from	effect	879:884	arg1	ability					916:922	ability	916:922	ability	916:922	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	5	42	from	effect	879:884	arg1	mobility					903:910	molecular mobility	893:910	molecular mobility	893:910	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	7	43	theme	drug	1334:1337	arg1	concentration					1276:1288	the concentration	1272:1288	the concentration	1272:1288	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	7	43	theme	drug	1334:1337	arg1	activity					1312:1319	the thermodynamic activity	1294:1319	the thermodynamic activity of dissolved drug	1294:1337	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	7	44	theme	thermodynamic	1298:1310	arg1	activity					1312:1319	the thermodynamic activity	1294:1319	the thermodynamic activity of dissolved drug	1294:1337	In other words, that drug flux from aqueous cyclodextrin solutions through lipophilic membranes depends on both the concentration and the thermodynamic activity of dissolved drug.					
35487262	5	45	theme	hydrophilic	715:725	arg1	cyclodextrins					727:739	the hydrophilic cyclodextrins	711:739	the hydrophilic cyclodextrins	711:739	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	8	46	theme	maximum	1470:1476	arg1	value					1478:1482	their maximum value	1464:1482	their maximum value	1464:1482	Maximum flux is obtained when both the drug concentration and thermodynamic activity of the dissolved drug molecules are at their maximum value.					
35487262	2	47	theme	drug	367:370	arg1	permeation					372:381	drug permeation	367:381	drug permeation	367:381	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	4	48	theme	composition	637:647	arg1	effect					614:619	the effect	610:619	the effect of donor medium composition on drug permeation	610:666	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	2	49	theme	biological	310:319	arg1	membranes					321:329	biological membranes	310:329	biological membranes	310:329	Although the complexes are hydrophilic, and as such do not permeate biological membranes, the complexes are known to enhance drug permeation through lipophilic membranes and improve drug bioavailability after, for example, oral administration.					
35487262	1	50	theme	lipophilic	161:170	arg1	drugs					172:176	lipophilic drugs	161:176	lipophilic drugs	161:176	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	4	51	theme	medium	630:635	arg1	composition					637:647	donor medium composition	624:647	donor medium composition	624:647	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	5	52	theme	organic	790:796	arg1	cosolvents					798:807	organic cosolvents	790:807	organic cosolvents	790:807	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	1	53	theme	drugs	172:176	arg1	solubility					147:156	aqueous solubility	139:156	aqueous solubility of lipophilic drugs	139:176	Cyclodextrins are hydrophilic oligosaccharides that can increase aqueous solubility of lipophilic drugs through formation of water-soluble drug/cyclodextrin complexes.					
35487262	4	54	theme	drug	652:655	arg1	permeation					657:666	drug permeation	652:666	drug permeation	652:666	An artificial biomembrane (PermeaPad®) was used to study the effect of donor medium composition on drug permeation.					
35487262	6	55	theme	molecules	1035:1043	arg1	partition					1007:1015	that partition	1002:1015	that partition of dissolved drug molecules from the aqueous exterior into the membrane	1002:1087	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
35487262	5	56	theme	significant	867:877	arg1	effect					879:884	significant effect	867:884	significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane	867:993	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	5	57	theme	drug	938:941	arg1	molecules					943:951	lipophilic drug molecules	927:951	lipophilic drug molecules	927:951	It was observed that in aqueous solutions the hydrophilic cyclodextrins behave not like disperse systems but rather like organic cosolvents such as ethanol, increasing the solubility without having significant effect on the molecular mobility and ability of lipophilic drug molecules to partition into the lipophilic membrane.					
35487262	6	58	theme	aqueous	1054:1060	arg1	exterior					1062:1069	the aqueous exterior	1050:1069	the aqueous exterior	1050:1069	Also, that partition of dissolved drug molecules from the aqueous exterior into the membrane is at its maximum when their thermodynamic activity is at its maximum.					
36773872	2	0	theme	aqueous	501:507	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	0	theme	aqueous	501:507	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	6	1	theme	films	1263:1267	arg1	fabrication					1209:1219	the fabrication	1205:1219	the fabrication of hydrophobic cellulose/lignin composite films	1205:1267	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	2	2	theme	film	608:611	arg1	surface					580:586	the surface	576:586	the surface of a lignocellulose film (LCF)	576:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	1	3	theme	pulping	162:168	arg1	by-product					142:151	a by-product	140:151	a by-product of paper pulping	140:168	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	3	theme	pulping	162:168	arg1	lignin					117:122	lignin	117:122	lignin	117:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	3	theme	pulping	162:168	arg1	amounts					106:112	Large amounts	100:112	Large amounts of lignin	100:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	3	4	theme	lignin	699:704	arg1	spheres					716:722	lignin colloidal spheres	699:722	lignin colloidal spheres	699:722	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	1	5	theme	various	251:257	arg1	areas					259:263	various areas	251:263	various areas	251:263	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	2	6	theme	acid	496:499	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	6	theme	acid	496:499	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	7	theme	lignocellulose	593:606	arg1	LCF					614:616	LCF	614:616	LCF	614:616	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	7	theme	lignocellulose	593:606	arg1	film					608:611	a lignocellulose film	591:611	a lignocellulose film (LCF)	591:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	5	8	theme	%	1133:1133	arg1	increase					1135:1142	a ~50 % increase	1127:1142	a ~50 % increase in tensile strength	1127:1162	Simultaneously, auto-adhesion endowed the LSHF with a ~50 % increase in tensile strength.					
36773872	2	9	theme	acetic	549:554	arg1	lignin					561:566	acetic acid lignin	549:566	acetic acid lignin (AL) on the surface of a lignocellulose film (LCF)	549:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	5	10	theme	~50 	1129:1132	arg1	%					1133:1133	%	1133:1133	%	1133:1133	Simultaneously, auto-adhesion endowed the LSHF with a ~50 % increase in tensile strength.					
36773872	2	11	from	surface	580:586	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	11	from	surface	580:586	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	11	from	surface	580:586	arg1	auto-adhesion					532:544	auto-adhesion	532:544	auto-adhesion	532:544	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	6	12	theme	hydrophobic	1224:1234	arg1	films					1263:1267	hydrophobic cellulose/lignin composite films	1224:1267	hydrophobic cellulose/lignin composite films	1224:1267	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	2	13	from	self-assembly	474:486	arg1	surface					580:586	the surface	576:586	the surface of a lignocellulose film (LCF)	576:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	5	14	from	increase	1135:1142	arg1	strength					1155:1162	tensile strength	1147:1162	tensile strength	1147:1162	Simultaneously, auto-adhesion endowed the LSHF with a ~50 % increase in tensile strength.					
36773872	2	15	theme	value-added	281:291	arg1	utilization					293:303	the value-added utilization	277:303	the value-added utilization of agricultural waste and lignin	277:336	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	4	16	from	240 s	889:893	arg1	WCA					866:868	the WCA	862:868	the WCA	862:868	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	16	from	240 s	889:893	arg1	stable					879:884	stable	879:884	stable	879:884	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	3	17	theme	colloidal	706:714	arg1	spheres					716:722	lignin colloidal spheres	699:722	lignin colloidal spheres	699:722	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	4	18	theme	%	966:966	arg1	decrease					940:947	a lower WCA decrease	928:947	a lower WCA decrease (15.53 % - 25.55 % decrease)	928:976	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	18	theme	%	966:966	arg1	decrease					968:975	15.53 % - 25.55 % decrease	950:975	15.53 % - 25.55 % decrease	950:975	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	2	19	theme	lignin	386:391	arg1	LSHF					430:433	LSHF	430:433	LSHF	430:433	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	19	theme	lignin	386:391	arg1	film					424:427	a lignin structure-designed hydrophobic film	384:427	a lignin structure-designed hydrophobic film (LSHF)	384:434	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	20	theme	solvent/anti-solvent	453:472	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	20	theme	solvent/anti-solvent	453:472	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	21	theme	acetic	489:494	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	21	theme	acetic	489:494	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	1	22	theme	Large	100:104	arg1	by-product					142:151	a by-product	140:151	a by-product of paper pulping	140:168	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	22	theme	Large	100:104	arg1	lignin					117:122	lignin	117:122	lignin	117:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	22	theme	Large	100:104	arg1	amounts					106:112	Large amounts	100:112	Large amounts of lignin	100:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	4	23	theme	%	956:956	arg1	decrease					940:947	a lower WCA decrease	928:947	a lower WCA decrease (15.53 % - 25.55 % decrease)	928:976	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	23	theme	%	956:956	arg1	decrease					968:975	15.53 % - 25.55 % decrease	950:975	15.53 % - 25.55 % decrease	950:975	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	6	24	theme	composite	1253:1261	arg1	films					1263:1267	hydrophobic cellulose/lignin composite films	1224:1267	hydrophobic cellulose/lignin composite films	1224:1267	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	0	25	theme	Lignin	0:5	arg1	self-assembly					7:19	Lignin self-assembly	0:19	Lignin self-assembly	0:19	Lignin self-assembly and auto-adhesion for hydrophobic cellulose/lignin composite film fabrication.					
36773872	2	26	theme	waste	321:325	arg1	utilization					293:303	the value-added utilization	277:303	the value-added utilization of agricultural waste and lignin	277:336	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	1	27	theme	tremendous	186:195	arg1	waste					197:201	a tremendous waste	184:201	a tremendous waste of natural resources with potential uses across various areas	184:263	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	2	28	theme	lignin	561:566	arg1	solution/n-hexane					509:525	acetic acid aqueous solution/n-hexane	489:525	acetic acid aqueous solution/n-hexane	489:525	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	28	theme	lignin	561:566	arg1	self-assembly					474:486	solvent/anti-solvent self-assembly	453:486	solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane)	453:526	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	28	theme	lignin	561:566	arg1	auto-adhesion					532:544	auto-adhesion	532:544	auto-adhesion	532:544	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	1	29	theme	lignin	117:122	arg1	by-product					142:151	a by-product	140:151	a by-product of paper pulping	140:168	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	29	theme	lignin	117:122	arg1	lignin					117:122	lignin	117:122	lignin	117:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	1	29	theme	lignin	117:122	arg1	amounts					106:112	Large amounts	100:112	Large amounts of lignin	100:122	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	4	30	theme	%	998:998	arg1	LCF					987:989	the LCF	983:989	the LCF (41.97 % - 61.11 % decrease)	983:1018	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	30	theme	%	998:998	arg1	decrease					1010:1017	41.97 % - 61.11 % decrease	992:1017	41.97 % - 61.11 % decrease	992:1017	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	3	31	from	~80°	789:792	arg1	WCA					779:781	WCA	779:781	WCA	779:781	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	3	31	from	~80°	789:792	arg1	angle					772:776	the water contact angle	754:776	the water contact angle (WCA) from ~80° to ~130°	754:801	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	3	32	theme	morphology	627:636	arg1	structure					638:646	the morphology structure	623:646	the morphology structure	623:646	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	4	33	theme	%	1008:1008	arg1	LCF					987:989	the LCF	983:989	the LCF (41.97 % - 61.11 % decrease)	983:1018	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	33	theme	%	1008:1008	arg1	decrease					1010:1017	41.97 % - 61.11 % decrease	992:1017	41.97 % - 61.11 % decrease	992:1017	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	2	34	theme	film	424:427	arg1	fabrication					369:379	the fabrication	365:379	the fabrication of a lignin structure-designed hydrophobic film (LSHF)	365:434	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	0	35	theme	hydrophobic	43:53	arg1	fabrication					87:97	hydrophobic cellulose/lignin composite film fabrication	43:97	hydrophobic cellulose/lignin composite film fabrication	43:97	Lignin self-assembly and auto-adhesion for hydrophobic cellulose/lignin composite film fabrication.					
36773872	1	36	with	waste	197:201	arg1	potential					229:237	potential uses	229:242	potential uses across various areas	229:263	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	2	37	theme	hydrophobic	412:422	arg1	LSHF					430:433	LSHF	430:433	LSHF	430:433	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	37	theme	hydrophobic	412:422	arg1	film					424:427	a lignin structure-designed hydrophobic film	384:427	a lignin structure-designed hydrophobic film (LSHF)	384:434	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	1	38	theme	natural	206:212	arg1	resources					214:222	natural resources	206:222	natural resources	206:222	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	4	39	theme	lower	930:934	arg1	decrease					940:947	a lower WCA decrease	928:947	a lower WCA decrease (15.53 % - 25.55 % decrease)	928:976	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	39	theme	lower	930:934	arg1	decrease					968:975	15.53 % - 25.55 % decrease	950:975	15.53 % - 25.55 % decrease	950:975	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	3	40	theme	water	758:762	arg1	WCA					779:781	WCA	779:781	WCA	779:781	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	3	40	theme	water	758:762	arg1	angle					772:776	the water contact angle	754:776	the water contact angle (WCA) from ~80° to ~130°	754:801	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	2	41	theme	acid	556:559	arg1	lignin					561:566	acetic acid lignin	549:566	acetic acid lignin (AL) on the surface of a lignocellulose film (LCF)	549:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	4	42	from	stable	879:884	arg1	240 s					889:893	240 s	889:893	240 s	889:893	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	43	theme	%	1062:1062	arg1	auto-adhesion					1043:1055	auto-adhesion	1043:1055	auto-adhesion (100 % decrease)	1043:1072	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	43	theme	%	1062:1062	arg1	decrease					1064:1071	100 % decrease	1058:1071	100 % decrease	1058:1071	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	1	44	theme	resources	214:222	arg1	waste					197:201	a tremendous waste	184:201	a tremendous waste of natural resources with potential uses across various areas	184:263	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	0	45	theme	composite	72:80	arg1	fabrication					87:97	hydrophobic cellulose/lignin composite film fabrication	43:97	hydrophobic cellulose/lignin composite film fabrication	43:97	Lignin self-assembly and auto-adhesion for hydrophobic cellulose/lignin composite film fabrication.					
36773872	2	46	dep	lignin	561:566	arg1	AL					569:570	AL	569:570	AL	569:570	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	6	47	theme	cellulose/lignin	1236:1251	arg1	films					1263:1267	hydrophobic cellulose/lignin composite films	1224:1267	hydrophobic cellulose/lignin composite films	1224:1267	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	1	48	dep	potential	229:237	arg1	uses					239:242	uses	239:242	uses	239:242	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	0	49	theme	cellulose/lignin	55:70	arg1	fabrication					87:97	hydrophobic cellulose/lignin composite film fabrication	43:97	hydrophobic cellulose/lignin composite film fabrication	43:97	Lignin self-assembly and auto-adhesion for hydrophobic cellulose/lignin composite film fabrication.					
36773872	4	50	theme	lignin	854:859	arg1	auto-adhesion					837:849	the auto-adhesion	833:849	the auto-adhesion of lignin	833:859	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	2	51	from	auto-adhesion	532:544	arg1	surface					580:586	the surface	576:586	the surface of a lignocellulose film (LCF)	576:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	6	52	theme	novel	1186:1190	arg1	strategy					1192:1199	a novel strategy	1184:1199	a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films	1184:1267	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	2	53	theme	agricultural	308:319	arg1	waste					321:325	agricultural waste	308:325	agricultural waste	308:325	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	54	from	lignin	561:566	arg1	surface					580:586	the surface	576:586	the surface of a lignocellulose film (LCF)	576:617	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	4	55	theme	WCA	936:938	arg1	decrease					940:947	a lower WCA decrease	928:947	a lower WCA decrease (15.53 % - 25.55 % decrease)	928:976	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	55	theme	WCA	936:938	arg1	decrease					968:975	15.53 % - 25.55 % decrease	950:975	15.53 % - 25.55 % decrease	950:975	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	3	56	contain	had	667:669	arg2	surface					679:685	a rough surface	671:685	a rough surface	671:685	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	3	56	contain	had	667:669	arg1	LSHF					662:665	the LSHF	658:665	the LSHF	658:665	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	4	57	contain	had	924:926	arg1	LSHF					919:922	the LSHF	915:922	the LSHF	915:922	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	57	contain	had	924:926	arg2	decrease					968:975	15.53 % - 25.55 % decrease	950:975	15.53 % - 25.55 % decrease	950:975	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	4	57	contain	had	924:926	arg2	decrease					940:947	a lower WCA decrease	928:947	a lower WCA decrease (15.53 % - 25.55 % decrease)	928:976	Furthermore, benefiting from the auto-adhesion of lignin, the WCA was more stable in 240 s, demonstrating that the LSHF had a lower WCA decrease (15.53 % - 25.55 % decrease) than the LCF (41.97 % - 61.11 % decrease) and the sample without auto-adhesion (100 % decrease).					
36773872	2	58	theme	lignin	331:336	arg1	utilization					293:303	the value-added utilization	277:303	the value-added utilization of agricultural waste and lignin	277:336	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	6	59	theme	lignin	1273:1278	arg1	self-assembly					1280:1292	lignin self-assembly	1273:1292	lignin self-assembly	1273:1292	This work provides a novel strategy for the fabrication of hydrophobic cellulose/lignin composite films via lignin self-assembly and auto-adhesion.					
36773872	2	60	theme	structure-designed	393:410	arg1	LSHF					430:433	LSHF	430:433	LSHF	430:433	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	2	60	theme	structure-designed	393:410	arg1	film					424:427	a lignin structure-designed hydrophobic film	384:427	a lignin structure-designed hydrophobic film (LSHF)	384:434	To achieve the value-added utilization of agricultural waste and lignin, we developed a method for the fabrication of a lignin structure-designed hydrophobic film (LSHF) directly through solvent/anti-solvent self-assembly (acetic acid aqueous solution/n-hexane) and auto-adhesion of acetic acid lignin (AL) on the surface of a lignocellulose film (LCF).					
36773872	5	61	theme	tensile	1147:1153	arg1	strength					1155:1162	tensile strength	1147:1162	tensile strength	1147:1162	Simultaneously, auto-adhesion endowed the LSHF with a ~50 % increase in tensile strength.					
36773872	0	62	theme	film	82:85	arg1	fabrication					87:97	hydrophobic cellulose/lignin composite film fabrication	43:97	hydrophobic cellulose/lignin composite film fabrication	43:97	Lignin self-assembly and auto-adhesion for hydrophobic cellulose/lignin composite film fabrication.					
36773872	3	63	theme	rough	673:677	arg1	surface					679:685	a rough surface	671:685	a rough surface	671:685	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	5	64	with	endowed	1105:1111	arg1	increase					1135:1142	a ~50 % increase	1127:1142	a ~50 % increase in tensile strength	1127:1162	Simultaneously, auto-adhesion endowed the LSHF with a ~50 % increase in tensile strength.					
36773872	1	65	theme	paper	156:160	arg1	pulping					162:168	paper pulping	156:168	paper pulping	156:168	Large amounts of lignin are produced as a by-product of paper pulping, resulting in a tremendous waste of natural resources with potential uses across various areas.					
36773872	3	66	theme	contact	764:770	arg1	WCA					779:781	WCA	779:781	WCA	779:781	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
36773872	3	66	theme	contact	764:770	arg1	angle					772:776	the water contact angle	754:776	the water contact angle (WCA) from ~80° to ~130°	754:801	As the morphology structure revealed, the LSHF had a rough surface composed of lignin colloidal spheres, which significantly improved the water contact angle (WCA) from ~80° to ~130°.					
35152020	4	0	from	ratio	619:623	arg1	1:1					628:630	1:1	628:630	1:1	628:630	And continuous structure was formed of composite mixture with the CMC/gelatin ratio in 1:1.					
35152020	5	1	theme	forming	650:656	arg1	solution					658:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	1	2	theme	environmental	157:169	arg1	temperature					171:181	environmental temperature	157:181	environmental temperature	157:181	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	1	3	theme	cellulose	273:281	arg1	films					289:293	carboxymethyl cellulose (CMC) films	259:293	carboxymethyl cellulose (CMC) films	259:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	6	4	theme	films	795:799	arg1	surface					801:807	the films surface	791:807	the films surface	791:807	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	1	5	theme	temperature	171:181	arg1	Effects					142:148	Effects	142:148	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films	142:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	4	6	theme	composite	580:588	arg1	mixture					590:596	composite mixture	580:596	composite mixture	580:596	And continuous structure was formed of composite mixture with the CMC/gelatin ratio in 1:1.					
35152020	7	7	theme	films	959:963	arg1	structure					965:973	the films structure	955:973	the films structure	955:973	Correspondingly, the mechanical properties and water vapor permeability were altered with the films structure.					
35152020	1	8	theme	CMC	284:286	arg1	films					289:293	carboxymethyl cellulose (CMC) films	259:293	carboxymethyl cellulose (CMC) films	259:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	8	9	theme	films	1025:1029	arg1	structure					998:1006	the surface structure	986:1006	the surface structure of the composite films	986:1029	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	2	10	theme	barrier	372:378	arg1	properties					380:389	The mechanical and water vapor barrier properties	341:389	properties	380:389	The mechanical and water vapor barrier properties of the films were also evaluated.					
35152020	3	11	theme	uniform	485:491	arg1	network					493:499	a uniform network	483:499	a uniform network	483:499	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	3	12	theme	chloride	531:538	arg1	solution					508:515	the solution	504:515	the solution of 5% calcium chloride	504:538	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	2	13	theme	films	398:402	arg1	mechanical					345:354	mechanical	345:354	mechanical	345:354	The mechanical and water vapor barrier properties of the films were also evaluated.					
35152020	3	14	theme	CMC	449:451	arg1	molecules					453:461	CMC molecules	449:461	CMC molecules	449:461	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	0	15	theme	different	106:114	arg1	temperature					116:126	different temperature	106:126	different temperature	106:126	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	8	16	theme	surface	990:996	arg1	structure					998:1006	the surface structure	986:1006	the surface structure of the composite films	986:1029	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	1	17	theme	relative	187:194	arg1	humidity					196:203	relative humidity	187:203	relative humidity	187:203	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	5	18	theme	CMC/Gel	637:643	arg1	solution					658:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	1	19	from	Effects	142:148	arg1	ultrastructure					241:254	the surface ultrastructure	229:254	the surface ultrastructure of carboxymethyl cellulose (CMC) films	229:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	1	20	theme	humidity	196:203	arg1	Effects					142:148	Effects	142:148	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films	142:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	1	21	theme	films	289:293	arg1	ultrastructure					241:254	the surface ultrastructure	229:254	the surface ultrastructure of carboxymethyl cellulose (CMC) films	229:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	5	22	theme	film	645:648	arg1	solution					658:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution	633:665	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	7	23	theme	water	912:916	arg1	permeability					924:935	water vapor permeability	912:935	water vapor permeability	912:935	Correspondingly, the mechanical properties and water vapor permeability were altered with the films structure.					
35152020	1	24	dep	temperature	171:181	arg1	the					153:155	the	153:155	the	153:155	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	6	25	theme	holes	782:786	arg1	numbers					771:777	numbers	771:777	numbers	771:777	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	6	25	theme	holes	782:786	arg1	size					762:765	size	762:765	size	762:765	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	1	26	theme	drying	208:213	arg1	conditions					215:224	drying conditions	208:224	drying conditions	208:224	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	0	27	theme	physical	15:22	arg1	properties					24:33	physical properties	15:33	physical properties	15:33	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	6	28	theme	relative	846:853	arg1	humidity					855:862	relative humidity	846:862	relative humidity	846:862	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	2	29	theme	vapor	366:370	arg1	properties					380:389	The mechanical and water vapor barrier properties	341:389	properties	380:389	The mechanical and water vapor barrier properties of the films were also evaluated.					
35152020	1	30	theme	conditions	215:224	arg1	humidity					196:203	relative humidity	187:203	relative humidity	187:203	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	1	30	theme	conditions	215:224	arg1	temperature					171:181	environmental temperature	157:181	environmental temperature	157:181	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	0	31	theme	carboxymethyl	38:50	arg1	films					62:66	carboxymethyl cellulose films	38:66	carboxymethyl cellulose films	38:66	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	6	32	dep	size	762:765	arg1	The					758:760	The	758:760	The	758:760	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	8	33	theme	water	1079:1083	arg1	vapor					1085:1089	water vapor	1079:1089	water vapor	1079:1089	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	5	34	with	23 °C	701:705	arg1	ventilation					729:739	ventilation	729:739	ventilation	729:739	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	5	35	with	2-8 °C	693:698	arg1	ventilation					729:739	ventilation	729:739	ventilation	729:739	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	1	36	theme	atomic	316:321	arg1	microscopy					329:338	atomic force microscopy	316:338	atomic force microscopy	316:338	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	6	37	from	numbers	771:777	arg1	surface					801:807	the films surface	791:807	the films surface	791:807	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	0	38	theme	films	62:66	arg1	Topography					0:9	Topography	0:9	Topography	0:9	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	0	38	theme	films	62:66	arg1	properties					24:33	physical properties	15:33	physical properties	15:33	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	1	39	theme	force	323:327	arg1	microscopy					329:338	atomic force microscopy	316:338	atomic force microscopy	316:338	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	5	40	with	23 °C	718:722	arg1	ventilation					729:739	ventilation	729:739	ventilation	729:739	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	2	41	theme	water	360:364	arg1	properties					380:389	The mechanical and water vapor barrier properties	341:389	properties	380:389	The mechanical and water vapor barrier properties of the films were also evaluated.					
35152020	0	42	theme	cellulose	52:60	arg1	films					62:66	carboxymethyl cellulose films	38:66	carboxymethyl cellulose films	38:66	Topography and physical properties of carboxymethyl cellulose films assembled with calcium and gelatin at different temperature and humidity.					
35152020	4	43	theme	continuous	545:554	arg1	structure					556:564	continuous structure	545:564	continuous structure	545:564	And continuous structure was formed of composite mixture with the CMC/gelatin ratio in 1:1.					
35152020	8	44	theme	vapor	1085:1089	arg1	delivery					1067:1074	delivery	1067:1074	delivery	1067:1074	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	8	44	theme	vapor	1085:1089	arg1	infiltration					1050:1061	infiltration	1050:1061	infiltration	1050:1061	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	8	45	theme	composite	1015:1023	arg1	films					1025:1029	the composite films	1011:1029	the composite films	1011:1029	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	3	46	theme	5	520:520	arg1	%					521:521	%	521:521	%	521:521	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	6	47	from	size	762:765	arg1	surface					801:807	the films surface	791:807	the films surface	791:807	The size and numbers of holes on the films surface were affected by the temperature and relative humidity.					
35152020	7	48	theme	vapor	918:922	arg1	permeability					924:935	water vapor permeability	912:935	water vapor permeability	912:935	Correspondingly, the mechanical properties and water vapor permeability were altered with the films structure.					
35152020	1	49	theme	surface	233:239	arg1	ultrastructure					241:254	the surface ultrastructure	229:254	the surface ultrastructure of carboxymethyl cellulose (CMC) films	229:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
35152020	4	50	theme	CMC/gelatin	607:617	arg1	ratio					619:623	the CMC/gelatin ratio	603:623	the CMC/gelatin ratio in 1:1	603:630	And continuous structure was formed of composite mixture with the CMC/gelatin ratio in 1:1.					
35152020	8	51	dep	infiltration	1050:1061	arg1	the					1046:1048	the	1046:1048	the	1046:1048	Moreover, the surface structure of the composite films was changed by the infiltration and delivery of water vapor when films were stored at 2-8 °C and -20 °C for days.					
35152020	5	52	with	50 °C	708:712	arg1	ventilation					729:739	ventilation	729:739	ventilation	729:739	The CMC/Gel film forming solution was respectively dried at 2-8 °C, 23 °C, 50 °C and 23 °C with ventilation to obtain films.					
35152020	3	53	theme	%	521:521	arg1	chloride					531:538	5% calcium chloride	520:538	5% calcium chloride	520:538	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	7	54	theme	mechanical	886:895	arg1	properties					897:906	the mechanical properties	882:906	the mechanical properties	882:906	Correspondingly, the mechanical properties and water vapor permeability were altered with the films structure.					
35152020	3	55	theme	calcium	523:529	arg1	chloride					531:538	5% calcium chloride	520:538	5% calcium chloride	520:538	The results showed that CMC molecules self-assembled into a uniform network at the solution of 5% calcium chloride.					
35152020	1	56	theme	carboxymethyl	259:271	arg1	films					289:293	carboxymethyl cellulose (CMC) films	259:293	carboxymethyl cellulose (CMC) films	259:293	Effects of the environmental temperature and relative humidity of drying conditions on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated by atomic force microscopy.					
36749165	3	0	theme	photocatalytic	319:332	arg1	performance					334:344	their photocatalytic performance	313:344	their photocatalytic performance	313:344	In this work, we improved their photocatalytic performance by doping WO3- with Cu.					
36749165	5	1	theme	aureus	567:572	arg1	inactivation					515:526	significant inactivation	503:526	significant inactivation of Escherichia coli and Staphylococcus aureus	503:572	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	4	2	theme	biocompatible	435:447	arg1	sponge					458:463	a highly biocompatible chitosan sponge	426:463	a highly biocompatible chitosan sponge	426:463	The wound dressing was prepared by loading Cu-WO3- into a highly biocompatible chitosan sponge.					
36749165	6	3	theme	wound	866:870	arg1	infections					872:881	bacterial wound infections	856:881	bacterial wound infections	856:881	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	4	theme	wound	757:761	arg1	healing					763:769	wound healing	757:769	wound healing	757:769	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	2	5	theme	WO3-	167:170	arg1	materials					186:194	WO3- semiconductor materials	167:194	WO3- semiconductor materials	167:194	WO3- semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria.					
36749165	5	6	theme	significant	503:513	arg1	inactivation					515:526	significant inactivation	503:526	significant inactivation of Escherichia coli and Staphylococcus aureus	503:572	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	5	7	dep	in	579:580	arg1	vitro					582:586	vitro	582:586	vitro	582:586	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	4	8	theme	loading	405:411	arg1	Cu-WO3-					413:419	loading Cu-WO3-	405:419	loading Cu-WO3-	405:419	The wound dressing was prepared by loading Cu-WO3- into a highly biocompatible chitosan sponge.					
36749165	4	9	theme	wound	374:378	arg1	dressing					380:387	The wound dressing	370:387	The wound dressing	370:387	The wound dressing was prepared by loading Cu-WO3- into a highly biocompatible chitosan sponge.					
36749165	5	10	theme	dressing	652:659	arg1	biosafety					635:643	the biosafety	631:643	the biosafety of the dressing	631:659	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	6	11	theme	sponge	710:715	arg1	dressings					717:725	composite sponge dressings	700:725	composite sponge dressings	700:725	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	12	dep	in	670:671	arg1	vivo					673:676	vivo	673:676	vivo	673:676	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	13	theme	photodynamic	832:843	arg1	therapy					845:851	photodynamic therapy	832:851	photodynamic therapy of bacterial wound infections	832:881	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	14	theme	chitosan	791:798	arg1	sponge					800:805	this composite chitosan sponge	776:805	this composite chitosan sponge	776:805	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	1	15	theme	potential	90:98	arg1	treatments					100:109	the potential treatments	86:109	the potential treatments for bacterial wound infections	86:140	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	5	16	theme	composite	470:478	arg1	dressing					487:494	The composite sponge dressing	466:494	The composite sponge dressing	466:494	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	5	17	theme	L929	607:610	arg1	cells					612:616	L929 cells	607:616	L929 cells	607:616	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	1	18	theme	treatments	100:109	arg1	One					79:81	One	79:81	One	79:81	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	1	18	theme	treatments	100:109	arg1	treatments					100:109	the potential treatments	86:109	the potential treatments for bacterial wound infections	86:140	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	5	19	theme	sponge	480:485	arg1	dressing					487:494	The composite sponge dressing	466:494	The composite sponge dressing	466:494	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	6	20	theme	composite	700:708	arg1	dressings					717:725	composite sponge dressings	700:725	composite sponge dressings	700:725	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	4	21	theme	chitosan	449:456	arg1	sponge					458:463	a highly biocompatible chitosan sponge	426:463	a highly biocompatible chitosan sponge	426:463	The wound dressing was prepared by loading Cu-WO3- into a highly biocompatible chitosan sponge.					
36749165	3	22	with	WO3-	356:359	arg1	Cu					366:367	Cu	366:367	Cu	366:367	In this work, we improved their photocatalytic performance by doping WO3- with Cu.					
36749165	6	23	theme	healing	684:690	arg1	trials					692:697	in vivo wound healing trials	670:697	in vivo wound healing trials	670:697	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	24	used	used	823:826	arg2	sponge					800:805	this composite chitosan sponge	776:805	this composite chitosan sponge	776:805	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	0	25	theme	Photodynamic	38:49	arg1	Therapy					51:57	Photodynamic Therapy	38:57	Photodynamic Therapy of Wound Infection	38:76	Chitosan Sponge/Cu-WO3- Composite for Photodynamic Therapy of Wound Infection.					
36749165	6	26	theme	infections	872:881	arg1	therapy					845:851	photodynamic therapy	832:851	photodynamic therapy of bacterial wound infections	832:881	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	0	27	theme	Wound	62:66	arg1	Infection					68:76	Wound Infection	62:76	Wound Infection	62:76	Chitosan Sponge/Cu-WO3- Composite for Photodynamic Therapy of Wound Infection.					
36749165	2	28	theme	semiconductor	172:184	arg1	materials					186:194	WO3- semiconductor materials	167:194	WO3- semiconductor materials	167:194	WO3- semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria.					
36749165	1	29	theme	bacterial	115:123	arg1	infections					131:140	bacterial wound infections	115:140	bacterial wound infections	115:140	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	6	30	theme	bacterial	856:864	arg1	infections					872:881	bacterial wound infections	856:881	bacterial wound infections	856:881	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	5	31	theme	in	579:580	arg1	assays					597:602	in vitro toxicity assays	579:602	in vitro toxicity assays on L929 cells	579:616	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	1	32	theme	wound	125:129	arg1	infections					131:140	bacterial wound infections	115:140	bacterial wound infections	115:140	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	6	33	theme	wound	678:682	arg1	healing					684:690	in vivo wound healing	670:690	in vivo wound healing trials	670:697	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	6	34	theme	composite	781:789	arg1	sponge					800:805	this composite chitosan sponge	776:805	this composite chitosan sponge	776:805	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	5	35	theme	toxicity	588:595	arg1	assays					597:602	in vitro toxicity assays	579:602	in vitro toxicity assays on L929 cells	579:616	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	2	36	theme	oxygen	218:223	arg1	species					225:231	reactive oxygen species	209:231	reactive oxygen species when exposed to light, which can inactivate bacteria	209:284	WO3- semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria.					
36749165	5	37	theme	coli	543:546	arg1	inactivation					515:526	significant inactivation	503:526	significant inactivation of Escherichia coli and Staphylococcus aureus	503:572	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	5	38	from	assays	597:602	arg1	cells					612:616	L929 cells	607:616	L929 cells	607:616	The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing.					
36749165	6	39	theme	in	670:671	arg1	healing					684:690	in vivo wound healing	670:690	in vivo wound healing trials	670:697	Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.					
36749165	2	40	theme	reactive	209:216	arg1	species					225:231	reactive oxygen species	209:231	reactive oxygen species when exposed to light, which can inactivate bacteria	209:284	WO3- semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria.					
36749165	0	41	dep	Sponge/Cu-WO3-	9:22	arg1	Composite					24:32	Composite	24:32	Composite	24:32	Chitosan Sponge/Cu-WO3- Composite for Photodynamic Therapy of Wound Infection.					
36749165	1	42	theme	photodynamic	145:156	arg1	therapy					158:164	photodynamic therapy	145:164	photodynamic therapy	145:164	One of the potential treatments for bacterial wound infections is photodynamic therapy.					
36749165	0	43	theme	Infection	68:76	arg1	Therapy					51:57	Photodynamic Therapy	38:57	Photodynamic Therapy of Wound Infection	38:76	Chitosan Sponge/Cu-WO3- Composite for Photodynamic Therapy of Wound Infection.					
37023876	0	0	theme	double-network	86:99	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	0	theme	double-network	86:99	arg1	analysis					126:133	Isotherm analysis	117:133	Isotherm analysis	117:133	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	0	theme	double-network	86:99	arg1	performance					153:163	recyclability performance	139:163	recyclability performance	139:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	6	1	theme	contaminants	907:918	arg1	data					894:897	the adsorption data	879:897	the adsorption data of both contaminants	879:918	Furthermore, the isotherm assessments showed that Langmuir-Freundlich can fit the adsorption data of both contaminants.					
37023876	7	2	theme	Langmuir-Freundlich	983:1001	arg1	model					1003:1007	the Langmuir-Freundlich model	979:1007	the Langmuir-Freundlich model	979:1007	Accordingly, the maximum adsorption capacities reached by the Langmuir-Freundlich model are 400.50 and 411.45 mg/g for MB and CR, respectively.					
37023876	2	3	theme	wastewater	342:351	arg1	treatment					353:361	wastewater treatment	342:361	wastewater treatment	342:361	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	4	4	theme	beads	616:620	arg1	capacity					598:605	the removal capacity	586:605	the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR)	586:699	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	0	5	theme	alginate	77:84	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	5	theme	alginate	77:84	arg1	analysis					126:133	Isotherm analysis	117:133	Isotherm analysis	117:133	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	5	theme	alginate	77:84	arg1	performance					153:163	recyclability performance	139:163	recyclability performance	139:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	8	6	from	capabilities	1115:1126	arg1	hydrogels					1149:1157	bead hydrogels	1144:1157	bead hydrogels	1144:1157	It is interesting to note that the bio-adsorption capabilities of MB and CR on bead hydrogels decreased with temperature.					
37023876	4	7	theme	Kinetic	528:534	arg1	approaches					565:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	10	8	theme	great	1396:1400	arg1	performance					1413:1423	a great adsorptive performance	1394:1423	a great adsorptive performance	1394:1423	The CGC/SA gel beads are therefore outstanding bio-adsorbents, offering a great adsorptive performance and regenerative abilities.					
37023876	0	9	theme	hydrogel	101:108	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	9	theme	hydrogel	101:108	arg1	analysis					126:133	Isotherm analysis	117:133	Isotherm analysis	117:133	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	9	theme	hydrogel	101:108	arg1	performance					153:163	recyclability performance	139:163	recyclability performance	139:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	7	10	theme	adsorption	946:955	arg1	capacities					957:966	the maximum adsorption capacities	934:966	the maximum adsorption capacities reached by the Langmuir-Freundlich model	934:1007	Accordingly, the maximum adsorption capacities reached by the Langmuir-Freundlich model are 400.50 and 411.45 mg/g for MB and CR, respectively.					
37023876	7	10	theme	adsorption	946:955	arg1	400.50					1013:1018	400.50	1013:1018	400.50	1013:1018	Accordingly, the maximum adsorption capacities reached by the Langmuir-Freundlich model are 400.50 and 411.45 mg/g for MB and CR, respectively.					
37023876	0	11	theme	Isotherm	117:124	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	11	theme	Isotherm	117:124	arg1	analysis					126:133	Isotherm analysis	117:133	Isotherm analysis	117:133	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	6	12	theme	adsorption	883:892	arg1	data					894:897	the adsorption data	879:897	the adsorption data of both contaminants	879:918	Furthermore, the isotherm assessments showed that Langmuir-Freundlich can fit the adsorption data of both contaminants.					
37023876	0	13	dep	beads	110:114	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	13	dep	beads	110:114	arg1	analysis					126:133	Isotherm analysis	117:133	Isotherm analysis	117:133	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	13	dep	beads	110:114	arg1	performance					153:163	recyclability performance	139:163	recyclability performance	139:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	5	14	theme	pseudo-second-order	768:786	arg1	model					788:792	the pseudo-second-order model	764:792	the pseudo-second-order model (PSO)	764:798	Also, the kinetics shows that the results can be explained by the pseudo-second-order model (PSO).					
37023876	5	14	theme	pseudo-second-order	768:786	arg1	PSO					795:797	PSO	795:797	PSO	795:797	Also, the kinetics shows that the results can be explained by the pseudo-second-order model (PSO).					
37023876	4	15	from	equilibrium	636:646	arg1	20 min					651:656	20 min	651:656	20 min	651:656	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	7	16	theme	maximum	938:944	arg1	capacities					957:966	the maximum adsorption capacities	934:966	the maximum adsorption capacities reached by the Langmuir-Freundlich model	934:1007	Accordingly, the maximum adsorption capacities reached by the Langmuir-Freundlich model are 400.50 and 411.45 mg/g for MB and CR, respectively.					
37023876	7	16	theme	maximum	938:944	arg1	400.50					1013:1018	400.50	1013:1018	400.50	1013:1018	Accordingly, the maximum adsorption capacities reached by the Langmuir-Freundlich model are 400.50 and 411.45 mg/g for MB and CR, respectively.					
37023876	2	17	dep	grounds	275:281	arg1	CGC					294:296	CGC	294:296	CGC	294:296	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	17	dep	grounds	275:281	arg1	cellulose					283:291	cellulose	283:291	cellulose (CGC)	283:297	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	17	dep	grounds	275:281	arg1	alginate					310:317	sodium alginate	303:317	sodium alginate (SA)	303:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	17	dep	grounds	275:281	arg1	SA					320:321	SA	320:321	SA	320:321	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	17	dep	grounds	275:281	arg1	grounds					275:281	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	4	18	theme	removal	590:596	arg1	capacity					598:605	the removal capacity	586:605	the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR)	586:699	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	10	19	theme	regenerative	1429:1440	arg1	abilities					1442:1450	regenerative abilities	1429:1450	regenerative abilities	1429:1450	The CGC/SA gel beads are therefore outstanding bio-adsorbents, offering a great adsorptive performance and regenerative abilities.					
37023876	10	20	theme	CGC/SA	1326:1331	arg1	beads					1337:1341	The CGC/SA gel beads	1322:1341	The CGC/SA gel beads	1322:1341	The CGC/SA gel beads are therefore outstanding bio-adsorbents, offering a great adsorptive performance and regenerative abilities.					
37023876	1	21	theme	new	205:207	arg1	adsorbents					222:231	new eco-friendly adsorbents	205:231	new eco-friendly adsorbents	205:231	This work describes the preparation of new eco-friendly adsorbents with a simple method.					
37023876	2	22	theme	sodium	303:308	arg1	SA					320:321	SA	320:321	SA	320:321	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	22	theme	sodium	303:308	arg1	alginate					310:317	sodium alginate	303:317	sodium alginate (SA)	303:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	22	theme	sodium	303:308	arg1	grounds					275:281	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	1	23	theme	eco-friendly	209:220	arg1	adsorbents					222:231	new eco-friendly adsorbents	205:231	new eco-friendly adsorbents	205:231	This work describes the preparation of new eco-friendly adsorbents with a simple method.					
37023876	0	24	theme	cationic	14:21	arg1	dyes					35:38	cationic and anionic dyes	14:38	cationic and anionic dyes	14:38	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	9	25	theme	thermodynamic	1215:1227	arg1	study					1229:1233	the thermodynamic study	1211:1233	the thermodynamic study	1211:1233	Besides, the results of the thermodynamic study evidenced that the bio-adsorption processes are favorable, spontaneous and exothermic.					
37023876	1	26	theme	adsorbents	222:231	arg1	preparation					190:200	the preparation	186:200	the preparation of new eco-friendly adsorbents	186:231	This work describes the preparation of new eco-friendly adsorbents with a simple method.					
37023876	0	27	theme	dyes	35:38	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of cationic and anionic dyes onto coffee grounds	0:58	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	9	28	theme	study	1229:1233	arg1	results					1200:1206	the results	1196:1206	the results of the thermodynamic study	1196:1233	Besides, the results of the thermodynamic study evidenced that the bio-adsorption processes are favorable, spontaneous and exothermic.					
37023876	2	29	theme	Gel	255:257	arg1	beads					259:263	Gel beads	255:263	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA)	255:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	0	30	theme	anionic	27:33	arg1	dyes					35:38	cationic and anionic dyes	14:38	cationic and anionic dyes	14:38	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	4	31	theme	adsorption	554:563	arg1	approaches					565:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	0	32	theme	recyclability	139:151	arg1	beads					110:114	alginate double-network hydrogel beads	77:114	alginate double-network hydrogel beads: Isotherm analysis and recyclability performance	77:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	0	32	theme	recyclability	139:151	arg1	performance					153:163	recyclability performance	139:163	recyclability performance	139:163	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	8	33	theme	CR	1138:1139	arg1	capabilities					1115:1126	the bio-adsorption capabilities	1096:1126	the bio-adsorption capabilities of MB and CR on bead hydrogels	1096:1157	It is interesting to note that the bio-adsorption capabilities of MB and CR on bead hydrogels decreased with temperature.					
37023876	0	34	theme	coffee	45:50	arg1	grounds					52:58	coffee grounds	45:58	coffee grounds	45:58	Adsorption of cationic and anionic dyes onto coffee grounds cellulose/sodium alginate double-network hydrogel beads: Isotherm analysis and recyclability performance.					
37023876	4	35	theme	thermodynamic	540:552	arg1	approaches					565:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches	528:574	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	8	36	theme	bio-adsorption	1100:1113	arg1	capabilities					1115:1126	the bio-adsorption capabilities	1096:1126	the bio-adsorption capabilities of MB and CR on bead hydrogels	1096:1157	It is interesting to note that the bio-adsorption capabilities of MB and CR on bead hydrogels decreased with temperature.					
37023876	3	37	theme	physicochemical	390:404	arg1	properties					406:415	the physicochemical properties	386:415	the physicochemical properties	386:415	Upon their synthesis, the physicochemical properties, performances and efficiency were analyzed by means of various structural and morphological characterizations.					
37023876	10	38	theme	adsorptive	1402:1411	arg1	performance					1413:1423	a great adsorptive performance	1394:1423	a great adsorptive performance	1394:1423	The CGC/SA gel beads are therefore outstanding bio-adsorbents, offering a great adsorptive performance and regenerative abilities.					
37023876	9	39	theme	bio-adsorption	1254:1267	arg1	favorable					1283:1291	favorable	1283:1291	favorable	1283:1291	Besides, the results of the thermodynamic study evidenced that the bio-adsorption processes are favorable, spontaneous and exothermic.					
37023876	9	39	theme	bio-adsorption	1254:1267	arg1	processes					1269:1277	the bio-adsorption processes	1250:1277	the bio-adsorption processes	1250:1277	Besides, the results of the thermodynamic study evidenced that the bio-adsorption processes are favorable, spontaneous and exothermic.					
37023876	3	40	theme	morphological	495:507	arg1	characterizations					509:525	various structural and morphological characterizations	472:525	various structural and morphological characterizations	472:525	Upon their synthesis, the physicochemical properties, performances and efficiency were analyzed by means of various structural and morphological characterizations.					
37023876	6	41	theme	isotherm	818:825	arg1	assessments					827:837	the isotherm assessments	814:837	the isotherm assessments	814:837	Furthermore, the isotherm assessments showed that Langmuir-Freundlich can fit the adsorption data of both contaminants.					
37023876	2	42	theme	grounds	275:281	arg1	beads					259:263	Gel beads	255:263	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA)	255:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	10	43	theme	gel	1333:1335	arg1	beads					1337:1341	The CGC/SA gel beads	1322:1341	The CGC/SA gel beads	1322:1341	The CGC/SA gel beads are therefore outstanding bio-adsorbents, offering a great adsorptive performance and regenerative abilities.					
37023876	3	44	theme	various	472:478	arg1	characterizations					509:525	various structural and morphological characterizations	472:525	various structural and morphological characterizations	472:525	Upon their synthesis, the physicochemical properties, performances and efficiency were analyzed by means of various structural and morphological characterizations.					
37023876	1	45	theme	simple	240:245	arg1	method					247:252	a simple method	238:252	a simple method	238:252	This work describes the preparation of new eco-friendly adsorbents with a simple method.					
37023876	2	46	theme	coffee	268:273	arg1	cellulose					283:291	cellulose	283:291	cellulose (CGC)	283:297	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	46	theme	coffee	268:273	arg1	alginate					310:317	sodium alginate	303:317	sodium alginate (SA)	303:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	2	46	theme	coffee	268:273	arg1	grounds					275:281	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	coffee grounds cellulose (CGC) and sodium alginate (SA)	268:322	Gel beads of coffee grounds cellulose (CGC) and sodium alginate (SA) were prepared for wastewater treatment.					
37023876	3	47	theme	structural	480:489	arg1	characterizations					509:525	various structural and morphological characterizations	472:525	various structural and morphological characterizations	472:525	Upon their synthesis, the physicochemical properties, performances and efficiency were analyzed by means of various structural and morphological characterizations.					
37023876	4	48	theme	Blue	672:675	arg1	Methylene					662:670	Methylene Blue	662:675	Methylene Blue (MB)	662:680	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	4	48	theme	Blue	672:675	arg1	MB					678:679	MB	678:679	MB	678:679	Kinetic and thermodynamic adsorption approaches evaluated the removal capacity of these beads which reached equilibrium in 20 min for Methylene Blue (MB) and Congo Red (CR).					
37023876	8	49	theme	MB	1131:1132	arg1	capabilities					1115:1126	the bio-adsorption capabilities	1096:1126	the bio-adsorption capabilities of MB and CR on bead hydrogels	1096:1157	It is interesting to note that the bio-adsorption capabilities of MB and CR on bead hydrogels decreased with temperature.					
37023876	8	50	theme	bead	1144:1147	arg1	hydrogels					1149:1157	bead hydrogels	1144:1157	bead hydrogels	1144:1157	It is interesting to note that the bio-adsorption capabilities of MB and CR on bead hydrogels decreased with temperature.					
36107869	9	0	from	moisture	1142:1149	arg1	rice					1210:1213	cooked parboiled rice	1193:1213	cooked parboiled rice	1193:1213	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	2	1	theme	traditional	331:341	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	1	theme	traditional	331:341	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	1	theme	traditional	331:341	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	1	theme	traditional	331:341	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	1	theme	traditional	331:341	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	1	theme	traditional	331:341	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	6	2	theme	68.8-90.5	888:896	arg1	%					897:897	%	897:897	%	897:897	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36107869	7	3	dep	high	948:951	arg1	%					979:979	1.1-7.2%	972:979	1.1-7.2%	972:979	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	6	4	theme	Digestible	801:810	arg1	starch					812:817	Digestible starch	801:817	Digestible starch of raw polished	801:833	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36107869	5	5	dep	%	732:732	arg1	DM					735:736	DM	735:736	DM	735:736	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	5	6	theme	higher	784:789	arg1	contents					791:798	higher contents	784:798	higher contents	784:798	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	2	7	theme	parboiled	321:329	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	7	theme	parboiled	321:329	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	7	theme	parboiled	321:329	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	7	theme	parboiled	321:329	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	7	theme	parboiled	321:329	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	7	theme	parboiled	321:329	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	5	8	with	high	702:705	arg1	fat					739:741	2.1-5% (DM) fat	727:741	2.1-5% (DM) fat	727:741	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	3	9	theme	Cooked	517:522	arg1	rice					534:537	Cooked parboiled rice	517:537	Cooked parboiled rice	517:537	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	9	10	theme	High	1137:1140	arg1	moisture					1142:1149	High moisture	1137:1149	High moisture	1137:1149	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	9	11	from	starch	1183:1188	arg1	rice					1210:1213	cooked parboiled rice	1193:1213	cooked parboiled rice	1193:1213	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	4	12	dep	low	632:634	arg1	%					641:641	<1.5%	637:641	<1.5%	637:641	Mineral content was low (<1.5%) regardless of processing.					
36107869	3	13	contain	contained	539:547	arg2	P<0.05					578:583	P<0.05	578:583	P<0.05	578:583	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	3	13	contain	contained	539:547	arg2	moisture					568:575	high moisture	563:575	high moisture (P<0.05)	563:584	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	3	13	contain	contained	539:547	arg1	rice					534:537	Cooked parboiled rice	517:537	Cooked parboiled rice	517:537	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	5	14	dep	raw	748:750	arg1	parboiled					767:775	parboiled	767:775	parboiled	767:775	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	5	14	dep	raw	748:750	arg1	unpolished					752:761	unpolished	752:761	unpolished	752:761	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	1	15	theme	lower	163:167	arg1	responses					179:187	lower glycaemic responses	163:187	lower glycaemic responses comparative to raw unpolished or polished rice	163:234	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	5	16	theme	Crude	670:674	arg1	protein					676:682	Crude protein	670:682	Crude protein	670:682	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	9	17	theme	low	1230:1232	arg1	GI					1234:1235	low GI	1230:1235	low GI	1230:1235	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	2	18	theme	glycaemic	272:280	arg1	GI					291:292	GI	291:292	GI	291:292	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	18	theme	glycaemic	272:280	arg1	indices					282:288	glycaemic indices	272:288	glycaemic indices (GI)	272:293	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	7	19	from	high	948:951	arg1	rice					966:969	parboiled rice	956:969	parboiled rice	956:969	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	7	19	from	high	948:951	arg1	rice					1033:1036	raw polished rice	1020:1036	raw polished rice	1020:1036	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	1	20	theme	glycaemic	169:177	arg1	responses					179:187	lower glycaemic responses	163:187	lower glycaemic responses comparative to raw unpolished or polished rice	163:234	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	0	21	theme	Lankan	4:9	arg1	rice					33:36	Sri Lankan traditional parboiled rice	0:36	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?	0:67	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?					
36107869	9	22	theme	high	1152:1155	arg1	starch					1167:1172	high resistant starch	1152:1172	high resistant starch	1152:1172	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	7	23	theme	raw	1020:1022	arg1	rice					1033:1036	raw polished rice	1020:1036	raw polished rice	1020:1036	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	4	24	theme	Mineral	612:618	arg1	content					620:626	Mineral content	612:626	Mineral content	612:626	Mineral content was low (<1.5%) regardless of processing.					
36107869	0	25	theme	Sri	0:2	arg1	rice					33:36	Sri Lankan traditional parboiled rice	0:36	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?	0:67	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?					
36107869	9	26	theme	resistant	1157:1165	arg1	starch					1167:1172	high resistant starch	1152:1172	high resistant starch	1152:1172	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	7	27	theme	parboiled	956:964	arg1	rice					966:969	parboiled rice	956:969	parboiled rice	956:969	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	2	28	theme	raw	298:300	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	indices					282:288	glycaemic indices	272:288	glycaemic indices (GI)	272:293	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	GI					291:292	GI	291:292	GI	291:292	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	28	theme	raw	298:300	arg1	composition					256:266	the proximate composition	242:266	the proximate composition	242:266	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	29	theme	rice	354:357	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	0	30	theme	parboiled	23:31	arg1	rice					33:36	Sri Lankan traditional parboiled rice	0:36	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?	0:67	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?					
36107869	3	31	theme	high	563:566	arg1	moisture					568:575	high moisture	563:575	high moisture (P<0.05)	563:584	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	3	31	theme	high	563:566	arg1	P<0.05					578:583	P<0.05	578:583	P<0.05	578:583	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	0	32	dep	rice	33:36	arg1	panacea					41:47	A panacea	39:47	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?	0:67	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?					
36107869	8	33	theme	low	1104:1106	arg1	GI					1108:1109	low GI	1104:1109	low GI	1104:1109	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	0	34	theme	traditional	11:21	arg1	rice					33:36	Sri Lankan traditional parboiled rice	0:36	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?	0:67	Sri Lankan traditional parboiled rice: A panacea for hyperglycaemia?					
36107869	7	35	from	rice	966:969	arg1	high					948:951	high	948:951	high	948:951	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	5	36	dep	high	702:705	arg1	DM					718:719	5.8-11.0% DM	708:719	5.8-11.0% DM	708:719	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	7	37	from	rice	1033:1036	arg1	high					948:951	high	948:951	high	948:951	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	1	38	theme	Lankan	131:136	arg1	rice					150:153	parboiled Sri Lankan traditional rice	117:153	parboiled Sri Lankan traditional rice	117:153	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	8	39	theme	parboiled	1056:1064	arg1	parboiled					1056:1064	parboiled	1056:1064	parboiled	1056:1064	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	8	39	theme	parboiled	1056:1064	arg1	polished					1074:1081	polished	1074:1081	polished	1074:1081	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	8	39	theme	parboiled	1056:1064	arg1	varieties					1043:1051	All varieties	1039:1051	All varieties of parboiled and raw polished	1039:1081	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	2	40	theme	comparative	481:491	arg1	data					493:496	comparative data	481:496	comparative data	481:496	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	7	41	theme	polished	1024:1031	arg1	rice					1033:1036	raw polished rice	1020:1036	raw polished rice	1020:1036	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	1	42	theme	unpolished	208:217	arg1	rice					231:234	raw unpolished or polished rice	204:234	raw unpolished or polished rice	204:234	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	5	43	theme	5.8-11.0	708:715	arg1	%					716:716	%	716:716	%	716:716	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	9	44	theme	low	1179:1181	arg1	starch					1183:1188	low starch	1179:1188	low starch	1179:1188	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	9	45	theme	cooked	1193:1198	arg1	rice					1210:1213	cooked parboiled rice	1193:1213	cooked parboiled rice	1193:1213	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	5	46	theme	2.1-5	727:731	arg1	%					732:732	%	732:732	%	732:732	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	9	47	from	starch	1167:1172	arg1	rice					1210:1213	cooked parboiled rice	1193:1213	cooked parboiled rice	1193:1213	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	7	48	with	high	948:951	arg1	fibre					1011:1015	fibre	1011:1015	fibre	1011:1015	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	5	49	theme	%	716:716	arg1	DM					718:719	5.8-11.0% DM	708:719	5.8-11.0% DM	708:719	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	9	50	theme	unpolished	1253:1262	arg1	rice					1280:1283	raw unpolished or raw polished rice	1249:1283	raw unpolished or raw polished rice	1249:1283	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	3	51	theme	parboiled	524:532	arg1	rice					534:537	Cooked parboiled rice	517:537	Cooked parboiled rice	517:537	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	6	52	theme	polished	826:833	arg1	starch					812:817	Digestible starch	801:817	Digestible starch of raw polished	801:833	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36107869	1	53	theme	traditional	138:148	arg1	rice					150:153	parboiled Sri Lankan traditional rice	117:153	parboiled Sri Lankan traditional rice	117:153	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	8	54	theme	high	1115:1118	arg1	GI					1120:1121	high GI	1115:1121	high GI	1115:1121	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	6	55	theme	raw	822:824	arg1	polished					826:833	raw polished	822:833	raw polished	822:833	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36107869	7	56	theme	Resistant	904:912	arg1	starch					914:919	Resistant starch	904:919	Resistant starch	904:919	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	2	57	dep	varieties	377:385	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	Batapola					400:407	Batapola	400:407	Batapola	400:407	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	Unakola					432:438	Unakola	432:438	Unakola	432:438	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	Dik					413:415	Dik	413:415	Dik	413:415	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	57	dep	varieties	377:385	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	1	58	theme	parboiled	117:125	arg1	rice					150:153	parboiled Sri Lankan traditional rice	117:153	parboiled Sri Lankan traditional rice	117:153	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	9	59	theme	parboiled	1200:1208	arg1	rice					1210:1213	cooked parboiled rice	1193:1213	cooked parboiled rice	1193:1213	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	1	60	theme	polished	222:229	arg1	rice					231:234	raw unpolished or polished rice	204:234	raw unpolished or polished rice	204:234	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	3	61	theme	raw	598:600	arg1	polished					602:609	raw polished	598:609	raw polished	598:609	Cooked parboiled rice contained significantly high moisture (P<0.05) than raw or raw polished.					
36107869	5	62	theme	%	732:732	arg1	fat					739:741	2.1-5% (DM) fat	727:741	2.1-5% (DM) fat	727:741	Crude protein was comparatively high (5.8-11.0% DM) with 2.1-5% (DM) fat with raw unpolished and parboiled having higher contents.					
36107869	1	63	theme	Sri	127:129	arg1	rice					150:153	parboiled Sri Lankan traditional rice	117:153	parboiled Sri Lankan traditional rice	117:153	The research aimed to scientifically prove that parboiled Sri Lankan traditional rice elicits lower glycaemic responses comparative to raw unpolished or polished rice.					
36107869	7	64	dep	significantly	925:937	arg1	P<0.05					940:945	P<0.05	940:945	P<0.05	940:945	Resistant starch was significantly (P<0.05) high in parboiled rice (1.1-7.2%) with the least total dietary fibre in raw polished rice.					
36107869	2	65	theme	polished	307:314	arg1	composition					256:266	the proximate composition	242:266	the proximate composition	242:266	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	66	theme	proximate	246:254	arg1	composition					256:266	the proximate composition	242:266	the proximate composition	242:266	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	9	67	theme	polished	1271:1278	arg1	rice					1280:1283	raw unpolished or raw polished rice	1249:1283	raw unpolished or raw polished rice	1249:1283	High moisture, high resistant starch, and low starch in cooked parboiled rice contributed to low GI compared to raw unpolished or raw polished rice.					
36107869	2	68	theme	Lankan	347:352	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	68	theme	Lankan	347:352	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	68	theme	Lankan	347:352	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	68	theme	Lankan	347:352	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	68	theme	Lankan	347:352	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	68	theme	Lankan	347:352	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	8	69	theme	polished	1074:1081	arg1	parboiled					1056:1064	parboiled	1056:1064	parboiled	1056:1064	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	8	69	theme	polished	1074:1081	arg1	polished					1074:1081	polished	1074:1081	polished	1074:1081	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	8	69	theme	polished	1074:1081	arg1	varieties					1043:1051	All varieties	1039:1051	All varieties of parboiled and raw polished	1039:1081	All varieties of parboiled and raw polished were found to elicit low GI and high GI respectively.					
36107869	2	70	dep	Oryza	360:364	arg1	L.					373:374	Oryza sativa L.	360:374	Oryza sativa L.	360:374	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	Oryza					360:364	Oryza	360:364	Oryza	360:364	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	Hangimuththan					451:463	Hangimuththan	451:463	Hangimuththan	451:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	raw					298:300	raw	298:300	raw	298:300	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	samba					440:444	samba	440:444	samba	440:444	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	varieties					377:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties	321:385	parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan	321:463	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	2	71	theme	Sri	343:345	arg1	wee					417:419	wee	417:419	wee	417:419	Thus the proximate composition and glycaemic indices (GI) of raw, raw polished, and parboiled traditional Sri Lankan rice (Oryza sativa L.) varieties Godaheenati, Batapola el, Dik wee, Dahanala, Unakola samba, and Hangimuththan were studied as comparative data are not available.					
36107869	6	72	theme	%	897:897	arg1	DM					899:900	68.8-90.5% DM	888:900	68.8-90.5% DM	888:900	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36107869	6	72	theme	%	897:897	arg1	parboiled					859:867	parboiled	859:867	parboiled	859:867	Digestible starch of raw polished was highest compared to parboiled or raw unpolished (68.8-90.5% DM).					
36929638	5	0	theme	turns	847:851	arg1	nm					881:882	λmax = 552 nm	870:882	λmax = 552 nm	870:882	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	0	theme	turns	847:851	arg1	greenish-yellow					853:867	paper surface turns greenish-yellow	833:867	paper surface turns greenish-yellow (λmax = 552 nm)	833:883	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	6	1	theme	different	1040:1048	arg1	concentrations					1050:1063	different concentrations	1040:1063	different concentrations of the anthocyanin extract	1040:1090	The thermochromic effects were investigated at different concentrations of the anthocyanin extract.					
36929638	1	2	from	screen-printing	201:215	arg1	presence					249:256	the presence	245:256	the presence of ferrous sulphate mordant	245:284	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	7	3	theme	vapochromic	1308:1318	arg1	effect					1320:1325	vapochromic effect	1308:1325	vapochromic effect	1308:1325	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	4	4	theme	colorimetric	682:693	arg1	probe					695:699	a colorimetric probe	680:699	a colorimetric probe in a binding agent without agglomeration	680:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	4	4	theme	colorimetric	682:693	arg1	films					583:587	Pink anthocyanin/resin nanocomposite films	546:587	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface	546:618	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	0	5	theme	extract	88:94	arg1	screen-printing					44:58	screen-printing	44:58	screen-printing of anthocyanin biomolecular extract	44:94	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	5	6	theme	CIE	762:764	arg1	studies					779:785	CIE colorimetric studies	762:785	CIE colorimetric studies	762:785	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	6	7	theme	extract	1084:1090	arg1	concentrations					1050:1063	different concentrations	1040:1063	different concentrations of the anthocyanin extract	1040:1090	The thermochromic effects were investigated at different concentrations of the anthocyanin extract.					
36929638	7	8	theme	gaseous	1263:1269	arg1	stimulus					1279:1286	the gaseous ammonia stimulus	1259:1286	the gaseous ammonia stimulus	1259:1286	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	4	9	theme	paper	606:610	arg1	surface					612:618	paper surface	606:618	paper surface	606:618	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	3	10	dep	L.	460:461	arg1	function					467:474	function	467:474	to function as spectroscopic probe in coordination with ferrous sulphate mordant	464:543	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	3	10	dep	L.	460:461	arg1	capitata					451:458	capitata	451:458	capitata	451:458	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	2	11	dep	Brassica	428:435	arg1	oleracea					437:444	Brassica oleracea var	428:448	Brassica oleracea var	428:448	Environmentally-friendly anthocyanin extract was obtained from red-cabbage (Brassica oleracea var.					
36929638	2	11	dep	Brassica	428:435	arg1	var					446:448	var	446:448	Brassica oleracea var	428:448	Environmentally-friendly anthocyanin extract was obtained from red-cabbage (Brassica oleracea var.					
36929638	5	12	from	°C	915:916	arg1	heating					890:896	heating	890:896	heating from 25 °C to 75 °C	890:916	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	6	13	theme	anthocyanin	1072:1082	arg1	extract					1084:1090	the anthocyanin extract	1068:1090	the anthocyanin extract	1068:1090	The thermochromic effects were investigated at different concentrations of the anthocyanin extract.					
36929638	4	14	from	probe	695:699	arg1	agent					714:718	a binding agent	704:718	a binding agent without agglomeration	704:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	4	15	theme	anthocyanin/resin	551:567	arg1	probe					695:699	a colorimetric probe	680:699	a colorimetric probe in a binding agent without agglomeration	680:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	4	15	theme	anthocyanin/resin	551:567	arg1	films					583:587	Pink anthocyanin/resin nanocomposite films	546:587	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface	546:618	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	5	16	theme	paper	833:837	arg1	nm					881:882	λmax = 552 nm	870:882	λmax = 552 nm	870:882	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	16	theme	paper	833:837	arg1	greenish-yellow					853:867	paper surface turns greenish-yellow	833:867	paper surface turns greenish-yellow (λmax = 552 nm)	833:883	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	1	17	theme	multi-stimuli	300:312	arg1	sheets					344:349	multi-stimuli responsive colorimetric paper sheets	300:349	multi-stimuli responsive colorimetric paper sheets	300:349	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	10	18	theme	cellulose	1636:1644	arg1	substrates					1646:1655	the printed cellulose substrates	1624:1655	the printed cellulose substrates	1624:1655	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	4	19	theme	Pink	546:549	arg1	probe					695:699	a colorimetric probe	680:699	a colorimetric probe in a binding agent without agglomeration	680:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	4	19	theme	Pink	546:549	arg1	films					583:587	Pink anthocyanin/resin nanocomposite films	546:587	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface	546:618	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	8	20	theme	current	1332:1338	arg1	strip					1347:1351	The current sensor strip	1328:1351	The current sensor strip	1328:1351	The current sensor strip showed a detection limit for NH3(aq) in the range of 50-300 ppm.					
36929638	5	21	theme	75	912:913	arg1	°C					906:907	°C	906:907	°C	906:907	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	10	22	theme	printed	1628:1634	arg1	substrates					1646:1655	the printed cellulose substrates	1624:1655	the printed cellulose substrates	1624:1655	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	9	23	theme	high	1462:1465	arg1	reversibility					1467:1479	high reversibility	1462:1479	high reversibility	1462:1479	Both thermochromism and vapochromism showed high reversibility without fatigue.					
36929638	8	24	theme	detection	1362:1370	arg1	limit					1372:1376	a detection limit	1360:1376	a detection limit for NH3(aq)	1360:1388	The current sensor strip showed a detection limit for NH3(aq) in the range of 50-300 ppm.					
36929638	10	25	theme	substrates	1646:1655	arg1	properties					1610:1619	the morphological and mechanical properties	1577:1619	the morphological and mechanical properties of the printed cellulose substrates	1577:1655	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	7	26	dep	changes	1163:1169	arg1	returns					1230:1236	returns	1230:1236	returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect	1230:1325	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	10	27	dep	studying	1513:1520	arg1	addition					1501:1508	addition	1501:1508	addition	1501:1508	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	4	28	theme	nanocomposite	569:581	arg1	probe					695:699	a colorimetric probe	680:699	a colorimetric probe in a binding agent without agglomeration	680:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	4	28	theme	nanocomposite	569:581	arg1	films					583:587	Pink anthocyanin/resin nanocomposite films	546:587	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface	546:618	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	7	29	theme	anthocyanin-printed	1136:1154	arg1	sheets					1156:1161	the anthocyanin-printed sheets	1132:1161	the anthocyanin-printed sheets	1132:1161	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	4	30	theme	anthocyanin	657:667	arg1	extract					669:675	anthocyanin extract	657:675	anthocyanin extract	657:675	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	2	31	dep	obtained	401:408	arg1	Brassica					428:435	Brassica	428:435	Brassica	428:435	Environmentally-friendly anthocyanin extract was obtained from red-cabbage (Brassica oleracea var.					
36929638	10	32	theme	morphological	1581:1593	arg1	properties					1610:1619	the morphological and mechanical properties	1577:1619	the morphological and mechanical properties of the printed cellulose substrates	1577:1655	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	7	33	dep	greenish-yellow	1192:1206	arg1	pink					1184:1187	pink	1184:1187	pink	1184:1187	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	1	34	theme	responsive	314:323	arg1	sheets					344:349	multi-stimuli responsive colorimetric paper sheets	300:349	multi-stimuli responsive colorimetric paper sheets	300:349	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	7	35	theme	sheets	1156:1161	arg1	color					1123:1127	the color	1119:1127	the color of the anthocyanin-printed sheets	1119:1161	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	2	36	theme	anthocyanin	377:387	arg1	extract					389:395	Environmentally-friendly anthocyanin extract	352:395	Environmentally-friendly anthocyanin extract	352:395	Environmentally-friendly anthocyanin extract was obtained from red-cabbage (Brassica oleracea var.					
36929638	1	37	theme	anthocyanin	222:232	arg1	extract					234:240	anthocyanin extract	222:240	anthocyanin extract	222:240	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	0	38	theme	authentication	21:34	arg1	film					36:39	novel authentication film	15:39	novel authentication film	15:39	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	1	39	theme	colorimetric	325:336	arg1	sheets					344:349	multi-stimuli responsive colorimetric paper sheets	300:349	multi-stimuli responsive colorimetric paper sheets	300:349	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	5	40	theme	λmax	798:801	arg1	film					813:816	the pink (λmax = 418 nm) film	788:816	the pink (λmax = 418 nm) film	788:816	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	40	theme	λmax	798:801	arg1	nm					809:810	λmax = 418 nm	798:810	λmax = 418 nm	798:810	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	2	41	theme	Environmentally-friendly	352:375	arg1	extract					389:395	Environmentally-friendly anthocyanin extract	352:395	Environmentally-friendly anthocyanin extract	352:395	Environmentally-friendly anthocyanin extract was obtained from red-cabbage (Brassica oleracea var.					
36929638	8	42	theme	sensor	1340:1345	arg1	strip					1347:1351	The current sensor strip	1328:1351	The current sensor strip	1328:1351	The current sensor strip showed a detection limit for NH3(aq) in the range of 50-300 ppm.					
36929638	0	43	theme	novel	15:19	arg1	film					36:39	novel authentication film	15:39	novel authentication film	15:39	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	1	44	theme	paper	338:342	arg1	sheets					344:349	multi-stimuli responsive colorimetric paper sheets	300:349	multi-stimuli responsive colorimetric paper sheets	300:349	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	5	45	theme	=	803:803	arg1	film					813:816	the pink (λmax = 418 nm) film	788:816	the pink (λmax = 418 nm) film	788:816	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	45	theme	=	803:803	arg1	nm					809:810	λmax = 418 nm	798:810	λmax = 418 nm	798:810	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	46	theme	25	903:904	arg1	°C					906:907	°C	906:907	°C	906:907	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	10	47	theme	mechanical	1599:1608	arg1	properties					1610:1619	the morphological and mechanical properties	1577:1619	the morphological and mechanical properties of the printed cellulose substrates	1577:1655	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	4	48	theme	extract	669:675	arg1	well-dispersion					638:652	well-dispersion	638:652	well-dispersion of anthocyanin extract	638:675	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	3	49	theme	ferrous	520:526	arg1	mordant					537:543	ferrous sulphate mordant	520:543	ferrous sulphate mordant	520:543	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	0	50	theme	film	36:39	arg1	Preparation					0:10	Preparation	0:10	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.	0:128	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	3	51	theme	spectroscopic	479:491	arg1	probe					493:497	spectroscopic probe	479:497	spectroscopic probe	479:497	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	3	52	theme	sulphate	528:535	arg1	mordant					537:543	ferrous sulphate mordant	520:543	ferrous sulphate mordant	520:543	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	5	53	theme	=	875:875	arg1	nm					881:882	λmax = 552 nm	870:882	λmax = 552 nm	870:882	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	53	theme	=	875:875	arg1	greenish-yellow					853:867	paper surface turns greenish-yellow	833:867	paper surface turns greenish-yellow (λmax = 552 nm)	833:883	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	54	theme	new	933:935	arg1	film					951:954	new thermochromic film	933:954	new thermochromic film for anticounterfeiting applications	933:990	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	8	55	theme	ppm	1413:1415	arg1	range					1397:1401	the range	1393:1401	the range of 50-300 ppm	1393:1415	The current sensor strip showed a detection limit for NH3(aq) in the range of 50-300 ppm.					
36929638	5	56	theme	surface	839:845	arg1	nm					881:882	λmax = 552 nm	870:882	λmax = 552 nm	870:882	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	56	theme	surface	839:845	arg1	greenish-yellow					853:867	paper surface turns greenish-yellow	833:867	paper surface turns greenish-yellow (λmax = 552 nm)	833:883	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	57	theme	pink	792:795	arg1	film					813:816	the pink (λmax = 418 nm) film	788:816	the pink (λmax = 418 nm) film	788:816	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	57	theme	pink	792:795	arg1	nm					809:810	λmax = 418 nm	798:810	λmax = 418 nm	798:810	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	1	58	theme	Novel	130:134	arg1	substrates					172:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	10	59	theme	composites	1565:1574	arg1	properties					1538:1547	the rheological properties	1522:1547	the rheological properties of the prepared composites	1522:1574	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	5	60	theme	colorimetric	766:777	arg1	studies					779:785	CIE colorimetric studies	762:785	CIE colorimetric studies	762:785	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	10	61	theme	rheological	1526:1536	arg1	properties					1538:1547	the rheological properties	1522:1547	the rheological properties of the prepared composites	1522:1574	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	7	62	theme	ammonia	1271:1277	arg1	stimulus					1279:1286	the gaseous ammonia stimulus	1259:1286	the gaseous ammonia stimulus	1259:1286	Upon exposure to NH3(g) , the color of the anthocyanin-printed sheets changes rapidly from pink to greenish-yellow, and then immediately returns to pink after taking the gaseous ammonia stimulus away, demonstrating vapochromic effect.					
36929638	1	63	theme	thermochromic	136:148	arg1	substrates					172:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	6	64	theme	thermochromic	997:1009	arg1	effects					1011:1017	The thermochromic effects	993:1017	The thermochromic effects	993:1017	The thermochromic effects were investigated at different concentrations of the anthocyanin extract.					
36929638	3	65	with	coordination	502:513	arg1	mordant					537:543	ferrous sulphate mordant	520:543	ferrous sulphate mordant	520:543	capitata L.) to function as spectroscopic probe in coordination with ferrous sulphate mordant.					
36929638	5	66	dep	°C	906:907	arg1	to					909:910	to	909:910	to	909:910	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	67	theme	λmax	870:873	arg1	nm					881:882	λmax = 552 nm	870:882	λmax = 552 nm	870:882	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	5	67	theme	λmax	870:873	arg1	greenish-yellow					853:867	paper surface turns greenish-yellow	833:867	paper surface turns greenish-yellow (λmax = 552 nm)	833:883	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	10	68	theme	prepared	1556:1563	arg1	composites					1565:1574	the prepared composites	1552:1574	the prepared composites	1552:1574	In addition to studying the rheological properties of the prepared composites, the morphological and mechanical properties of the printed cellulose substrates were also studied.					
36929638	4	69	theme	binding	706:712	arg1	agent					714:718	a binding agent	704:718	a binding agent without agglomeration	704:740	Pink anthocyanin/resin nanocomposite films immobilized onto paper surface were developed by well-dispersion of anthocyanin extract as a colorimetric probe in a binding agent without agglomeration.					
36929638	1	70	with	screen-printing	201:215	arg1	extract					234:240	anthocyanin extract	222:240	anthocyanin extract	222:240	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	5	71	theme	anticounterfeiting	960:977	arg1	applications					979:990	anticounterfeiting applications	960:990	anticounterfeiting applications	960:990	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	1	72	theme	vapochromic	154:164	arg1	substrates					172:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	1	73	theme	ferrous	261:267	arg1	mordant					278:284	ferrous sulphate mordant	261:284	ferrous sulphate mordant	261:284	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	0	74	theme	biomolecular	75:86	arg1	extract					88:94	anthocyanin biomolecular extract	63:94	anthocyanin biomolecular extract	63:94	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	1	75	theme	paper	166:170	arg1	substrates					172:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates	130:181	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	1	76	theme	sulphate	269:276	arg1	mordant					278:284	ferrous sulphate mordant	261:284	ferrous sulphate mordant	261:284	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36929638	0	77	theme	anthocyanin	63:73	arg1	extract					88:94	anthocyanin biomolecular extract	63:94	anthocyanin biomolecular extract	63:94	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	0	78	dep	Preparation	0:10	arg1	vapochromism					116:127	vapochromism	116:127	vapochromism	116:127	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	0	78	dep	Preparation	0:10	arg1	Thermochromism					97:110	Thermochromism	97:110	Thermochromism	97:110	Preparation of novel authentication film by screen-printing of anthocyanin biomolecular extract: Thermochromism and vapochromism.					
36929638	5	79	theme	thermochromic	937:949	arg1	film					951:954	new thermochromic film	933:954	new thermochromic film for anticounterfeiting applications	933:990	As demonstrated by CIE colorimetric studies, the pink (λmax = 418 nm) film deposited onto paper surface turns greenish-yellow (λmax = 552 nm) upon heating from 25 °C to 75 °C, demonstrating new thermochromic film for anticounterfeiting applications.					
36929638	1	80	theme	mordant	278:284	arg1	presence					249:256	the presence	245:256	the presence of ferrous sulphate mordant	245:284	Novel thermochromic and vapochromic paper substrates were prepared via screen-printing with anthocyanin extract in the presence of ferrous sulphate mordant, resulting in multi-stimuli responsive colorimetric paper sheets.					
36089084	6	0	theme	Vigna	935:939	arg1	mungo					941:945	Vigna mungo	935:945	Vigna mungo	935:945	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	5	1	theme	Elovich-kinetic	834:848	arg1	models					850:855	Elovich-kinetic models	834:855	Elovich-kinetic models	834:855	IBU adsorption onto CMC/PPY theoretically fits into the Langmuir isotherm and Elovich-kinetic models.					
36089084	4	2	theme	72.30	719:723	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	1	3	theme	toxic	261:265	arg1	effects					278:284	toxic biological effects	261:284	toxic biological effects	261:284	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	0	4	theme	carboxymethyl	94:106	arg1	CMC/PPY					119:125	CMC/PPY	119:125	CMC/PPY	119:125	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	0	4	theme	carboxymethyl	94:106	arg1	cellulose					108:116	carboxymethyl cellulose	94:116	carboxymethyl cellulose (CMC/PPY)	94:126	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	7	5	theme	growth	1091:1096	arg1	inhibition					1098:1107	growth inhibition	1091:1107	growth inhibition (58.52 % for VM, 60.84 % for VR)	1091:1140	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	3	6	from	20 nm	534:538	arg1	surface					551:557	the CMC surface	543:557	the CMC surface	543:557	Pyrrole was polymerized to polypyrrole whose average size was about 20 nm on the CMC surface.					
36089084	1	7	theme	biological	267:276	arg1	effects					278:284	toxic biological effects	261:284	toxic biological effects	261:284	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	7	8	dep	germination	1147:1157	arg1	%					1182:1182	90 %	1179:1182	90 % for VR	1179:1189	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	7	8	dep	germination	1147:1157	arg1	%					1166:1166	86.66 %	1160:1166	86.66 % for VM	1160:1173	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	2	9	with	composite	426:434	arg1	efficiency					454:463	high removal efficiency	441:463	high removal efficiency	441:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	7	10	dep	inhibition	1098:1107	arg1	%					1132:1132	60.84 %	1126:1132	60.84 % for VR	1126:1139	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	7	10	dep	inhibition	1098:1107	arg1	%					1116:1116	58.52 %	1110:1116	58.52 % for VM	1110:1123	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	2	11	theme	high	441:444	arg1	efficiency					454:463	high removal efficiency	441:463	high removal efficiency	441:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	4	12	theme	CMC/PPY	601:607	arg1	composite					609:617	CMC/PPY composite	601:617	CMC/PPY composite	601:617	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	7	13	theme	toxicity	980:987	arg1	study					989:993	The toxicity study	976:993	The toxicity study	976:993	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	2	14	theme	CMC/PPY	417:423	arg1	composite					426:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite	373:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency	373:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	7	15	theme	zebrafish	1063:1071	arg1	mortality					1073:1081	the zebrafish mortality	1059:1081	the zebrafish mortality (33 %)	1059:1088	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	7	15	theme	zebrafish	1063:1071	arg1	%					1087:1087	33 %	1084:1087	33 %	1084:1087	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	11	16	theme	pharmaceutical	1474:1487	arg1	IBU					1499:1501	pharmaceutical pollutant IBU	1474:1501	pharmaceutical pollutant IBU	1474:1501	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	5	17	theme	Langmuir	812:819	arg1	isotherm					821:828	the Langmuir isotherm	808:828	the Langmuir isotherm	808:828	IBU adsorption onto CMC/PPY theoretically fits into the Langmuir isotherm and Elovich-kinetic models.					
36089084	1	18	theme	living	289:294	arg1	organisms					296:304	living organisms	289:304	living organisms	289:304	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	10	19	theme	IBU	1346:1348	arg1	molecules					1350:1358	IBU molecules	1346:1358	IBU molecules	1346:1358	After adsorption, the LC50 increases to 2325.07 mg/L as IBU molecules get adsorbed by CMC/PPY.					
36089084	4	20	theme	removal	736:742	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	2	21	theme	carboxymethylcellulose/polypyrrole	381:414	arg1	composite					426:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite	373:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency	373:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	4	22	theme	removal	572:578	arg1	percentage					580:589	The maximum removal percentage	560:589	The maximum removal percentage of IBU by CMC/PPY composite	560:617	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	0	23	dep	modified	85:92	arg1	Case					129:132	Case	129:132	Case of ibuprofen pharmaceutical drug	129:165	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	11	24	theme	CMC/PPY	1434:1440	arg1	composite					1442:1450	CMC/PPY composite	1434:1450	CMC/PPY composite	1434:1450	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	2	25	theme	removal	446:452	arg1	efficiency					454:463	high removal efficiency	441:463	high removal efficiency	441:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	0	26	theme	toxicological	18:30	arg1	assessment					32:41	toxicological assessment	18:41	toxicological assessment	18:41	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	4	27	theme	IBU	594:596	arg1	percentage					580:589	The maximum removal percentage	560:589	The maximum removal percentage of IBU by CMC/PPY composite	560:617	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	2	28	theme	current	311:317	arg1	study					319:323	The current study	307:323	The current study	307:323	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	1	29	theme	anti-inflammatory	203:219	arg1	Ibuprofen					168:176	Ibuprofen	168:176	Ibuprofen (IBU)	168:182	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	1	29	theme	anti-inflammatory	203:219	arg1	drug					221:224	a non-steroidal anti-inflammatory drug	187:224	a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms	187:304	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	0	30	theme	emerging	46:53	arg1	contaminants					55:66	emerging contaminants	46:66	emerging contaminants	46:66	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	6	31	theme	Vigna	956:960	arg1	radiata					962:968	Vigna radiata	956:968	Vigna radiata (VR)	956:973	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	6	31	theme	Vigna	956:960	arg1	VR					971:972	VR	971:972	VR	971:972	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	0	32	theme	pharmaceutical	147:160	arg1	drug					162:165	ibuprofen pharmaceutical drug	137:165	ibuprofen pharmaceutical drug	137:165	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	4	33	with	pH 7	686:689	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	0	34	theme	ibuprofen	137:145	arg1	drug					162:165	ibuprofen pharmaceutical drug	137:165	ibuprofen pharmaceutical drug	137:165	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	6	35	theme	Phytotoxicity	867:879	arg1	assessment					881:890	Phytotoxicity assessment	867:890	Phytotoxicity assessment	867:890	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	0	36	with	assessment	32:41	arg1	polypyrrole					73:83	polypyrrole	73:83	polypyrrole	73:83	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	4	37	theme	dosage	667:672	arg1	0.02 g					674:679	dosage 0.02 g	667:679	dosage 0.02 g	667:679	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	11	38	theme	aqueous	1508:1514	arg1	solutions					1516:1524	aqueous solutions	1508:1524	aqueous solutions with their toxicological assessment	1508:1560	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	2	39	theme	aqueous	352:358	arg1	solutions					360:368	aqueous solutions	352:368	aqueous solutions	352:368	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	0	40	theme	contaminants	55:66	arg1	Sequestration					0:12	Sequestration	0:12	Sequestration	0:12	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	0	40	theme	contaminants	55:66	arg1	assessment					32:41	toxicological assessment	18:41	toxicological assessment	18:41	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	4	41	theme	maximum	564:570	arg1	percentage					580:589	The maximum removal percentage	560:589	The maximum removal percentage of IBU by CMC/PPY composite	560:617	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	0	42	theme	drug	162:165	arg1	Case					129:132	Case	129:132	Case of ibuprofen pharmaceutical drug	129:165	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	4	43	with	0.02 g	674:679	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	11	44	theme	pollutant	1489:1497	arg1	IBU					1499:1501	pharmaceutical pollutant IBU	1474:1501	pharmaceutical pollutant IBU	1474:1501	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	11	45	theme	toxicological	1537:1549	arg1	assessment					1551:1560	their toxicological assessment	1531:1560	their toxicological assessment	1531:1560	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	0	46	with	Sequestration	0:12	arg1	polypyrrole					73:83	polypyrrole	73:83	polypyrrole	73:83	Sequestration and toxicological assessment of emerging contaminants with polypyrrole modified carboxymethyl cellulose (CMC/PPY): Case of ibuprofen pharmaceutical drug.					
36089084	3	47	theme	average	511:517	arg1	size					519:522	size	519:522	size	519:522	Pyrrole was polymerized to polypyrrole whose average size was about 20 nm on the CMC surface.					
36089084	4	48	theme	%	753:753	arg1	mg/g					726:729	mg/g	726:729	mg/g	726:729	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	4	48	theme	%	753:753	arg1	removal					736:742	removal	736:742	removal of 83.17 %	736:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	4	48	theme	%	753:753	arg1	72.30					719:723	72.30	719:723	72.30 (mg/g)	719:730	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	11	49	with	solutions	1516:1524	arg1	assessment					1551:1560	their toxicological assessment	1531:1560	their toxicological assessment	1531:1560	These findings show the feasibility of preparing CMC/PPY composite to effectively remove pharmaceutical pollutant IBU from aqueous solutions with their toxicological assessment.					
36089084	4	50	theme	adsorption	696:705	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	1	51	theme	water	240:244	arg1	bodies					246:251	water bodies	240:251	water bodies causing toxic biological effects on living organisms	240:304	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	4	52	with	10 mg/L	658:664	arg1	capacity					707:714	adsorption capacity	696:714	adsorption capacity of 72.30 (mg/g) and removal of 83.17 %	696:753	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	1	53	theme	non-steroidal	189:201	arg1	Ibuprofen					168:176	Ibuprofen	168:176	Ibuprofen (IBU)	168:182	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	1	53	theme	non-steroidal	189:201	arg1	drug					221:224	a non-steroidal anti-inflammatory drug	187:224	a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms	187:304	Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug released into water bodies causing toxic biological effects on living organisms.					
36089084	2	54	theme	novel	375:379	arg1	composite					426:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite	373:434	a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency	373:463	The current study aims to eliminate IBU from aqueous solutions by a novel carboxymethylcellulose/polypyrrole (CMC/PPY) composite with high removal efficiency.					
36089084	4	55	theme	concentration	644:656	arg1	10 mg/L					658:664	initial concentration 10 mg/L	636:664	initial concentration 10 mg/L	636:664	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36089084	5	56	theme	IBU	756:758	arg1	adsorption					760:769	IBU adsorption	756:769	IBU adsorption onto CMC/PPY	756:782	IBU adsorption onto CMC/PPY theoretically fits into the Langmuir isotherm and Elovich-kinetic models.					
36089084	6	57	theme	mungo	941:945	arg1	zebrafish					912:920	zebrafish	912:920	zebrafish	912:920	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	6	57	theme	mungo	941:945	arg1	radiata					962:968	Vigna radiata	956:968	Vigna radiata (VR)	956:973	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	6	57	theme	mungo	941:945	arg1	VM					948:949	VM	948:949	VM	948:949	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	6	57	theme	mungo	941:945	arg1	seeds					926:930	seeds	926:930	seeds of Vigna mungo	926:945	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	6	57	theme	mungo	941:945	arg1	VR					971:972	VR	971:972	VR	971:972	Fish and Phytotoxicity assessment were performed with zebrafish and seeds of Vigna mungo (VM) and Vigna radiata (VR).					
36089084	7	58	theme	high	1037:1040	arg1	toxicity					1042:1049	high toxicity	1037:1049	high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR)	1037:1190	The toxicity study reveals that before adsorption, IBU shows high toxicity towards the zebrafish mortality (33 %), growth inhibition (58.52 % for VM, 60.84 % for VR), and germination (86.66 % for VM and 90 % for VR).					
36089084	3	59	theme	CMC	547:549	arg1	surface					551:557	the CMC surface	543:557	the CMC surface	543:557	Pyrrole was polymerized to polypyrrole whose average size was about 20 nm on the CMC surface.					
36089084	4	60	theme	initial	636:642	arg1	10 mg/L					658:664	initial concentration 10 mg/L	636:664	initial concentration 10 mg/L	636:664	The maximum removal percentage of IBU by CMC/PPY composite was optimized at initial concentration 10 mg/L, dosage 0.02 g, and pH 7 with adsorption capacity of 72.30 (mg/g) and removal of 83.17 %.					
36951357	3	0	theme	tip-surface	620:630	arg1	distance					632:639	The tip-surface distance	616:639	The tip-surface distance (lift distance) of 50 nm during the MFM analyses	616:688	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	3	0	theme	tip-surface	620:630	arg1	distance					647:654	lift distance	642:654	lift distance	642:654	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	3	1	theme	Waals	754:758	arg1	forces					760:765	the van der Waals forces	742:765	the van der Waals forces	742:765	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	0	2	theme	force	67:71	arg1	microscopy					73:82	magnetic force microscopy	58:82	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	7	3	theme	magnetic	1371:1378	arg1	domains					1380:1386	magnetic domains	1371:1386	magnetic domains	1371:1386	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	6	4	theme	cell	1162:1165	arg1	%					1180:1180	cell viability >70%	1162:1180	cell viability >70%	1162:1180	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	7	5	theme	cells	1468:1472	arg1	viability					1449:1457	the viability	1445:1457	the viability of HT-22 cells	1445:1472	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	5	6	theme	nm	1014:1015	arg1	values					978:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	0	7	theme	tracking	88:95	arg1	domains					106:112	tracking magnetic domains	88:112	tracking magnetic domains	88:112	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	5	8	theme	nm	1001:1002	arg1	values					978:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	3	9	theme	van	746:748	arg1	forces					760:765	the van der Waals forces	742:765	the van der Waals forces	742:765	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	2	10	theme	microscopy	430:439	arg1	techniques					483:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	1	11	theme	magnets	281:287	arg1	presence					269:276	the presence	265:276	the presence of magnets	265:287	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	12	theme	polymer	401:407	arg1	matrix					409:414	the polymer matrix	397:414	the polymer matrix	397:414	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	13	theme	oriented	366:373	arg1	PVA/SA-gMNP					381:391	PVA/SA-gMNP	381:391	PVA/SA-gMNP	381:391	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	13	theme	oriented	366:373	arg1	MNPs					375:378	magnetically oriented MNPs	353:378	magnetically oriented MNPs (PVA/SA-gMNP)	353:392	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	7	14	theme	roughness	1418:1426	arg1	increase					1398:1405	an increase	1395:1405	an increase	1395:1405	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	5	15	with	PVA/SA	904:909	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	2	16	theme	force	424:428	arg1	AFM					442:444	AFM	442:444	AFM	442:444	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	2	16	theme	force	424:428	arg1	microscopy					430:439	Atomic force microscopy	417:439	Atomic force microscopy (AFM)	417:445	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	6	17	theme	cell	1238:1241	arg1	proliferation					1243:1255	cell proliferation	1238:1255	cell proliferation	1238:1255	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	5	18	with	coatings	941:948	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	0	19	theme	magnetic	97:104	arg1	domains					106:112	tracking magnetic domains	88:112	tracking magnetic domains	88:112	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	5	20	theme	surface	955:961	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	6	21	theme	plastic	1212:1218	arg1	control					1203:1209	the control	1199:1209	the control (plastic plate) over 48 h	1199:1235	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	6	21	theme	plastic	1212:1218	arg1	plate					1220:1224	plastic plate	1212:1224	plastic plate	1212:1224	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	2	22	theme	domains	571:577	arg1	distribution					546:557	the distribution	542:557	the distribution of magnetic domains in the polymer matrix	542:599	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	5	23	with	SA	900:901	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	4	24	theme	MNPs	829:832	arg1	clusters					817:824	clusters	817:824	clusters of MNPs	817:832	The magnetic signal stemming from clusters of MNPs were more easily identified than that from isolated MNPs.					
36951357	2	25	theme	magnetic	562:569	arg1	domains					571:577	magnetic domains	562:577	magnetic domains	562:577	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	6	26	with	surfaces	1279:1286	arg1	PVA/SA-gMNP					1311:1321	PVA/SA-gMNP	1311:1321	PVA/SA-gMNP	1311:1321	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	6	26	with	surfaces	1279:1286	arg1	values					1303:1308	higher Ra values	1293:1308	higher Ra values (PVA/SA-gMNP)	1293:1322	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	0	27	theme	Poly	0:3	arg1	composites					46:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites	0:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	7	28	theme	domains	1380:1386	arg1	orientation					1356:1366	the orientation	1352:1366	the orientation of magnetic domains	1352:1386	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	6	29	theme	Ra	1300:1301	arg1	PVA/SA-gMNP					1311:1321	PVA/SA-gMNP	1311:1321	PVA/SA-gMNP	1311:1321	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	6	29	theme	Ra	1300:1301	arg1	values					1303:1308	higher Ra values	1293:1308	higher Ra values (PVA/SA-gMNP)	1293:1322	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	1	30	theme	/sodium	153:159	arg1	SA					171:172	SA	171:172	SA	171:172	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	30	theme	/sodium	153:159	arg1	alginate					161:168	poly(vinyl alcohol) (PVA)/sodium alginate	128:168	poly(vinyl alcohol) (PVA)/sodium alginate (SA)	128:173	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	2	31	from	distribution	546:557	arg1	matrix					594:599	the polymer matrix	582:599	the polymer matrix	582:599	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	3	32	theme	lift	642:645	arg1	distance					632:639	The tip-surface distance	616:639	The tip-surface distance (lift distance) of 50 nm during the MFM analyses	616:688	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	3	32	theme	lift	642:645	arg1	distance					647:654	lift distance	642:654	lift distance	642:654	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	2	33	theme	magnetic	451:458	arg1	microscopy					466:475	magnetic force microscopy	451:475	magnetic force microscopy (MFM)	451:481	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	2	33	theme	magnetic	451:458	arg1	MFM					478:480	MFM	478:480	MFM	478:480	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	6	34	theme	higher	1293:1298	arg1	PVA/SA-gMNP					1311:1321	PVA/SA-gMNP	1311:1321	PVA/SA-gMNP	1311:1321	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	6	34	theme	higher	1293:1298	arg1	values					1303:1308	higher Ra values	1293:1308	higher Ra values (PVA/SA-gMNP)	1293:1322	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	1	35	theme	alginate	161:168	arg1	MNPs					204:207	MNPs	204:207	MNPs	204:207	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	35	theme	alginate	161:168	arg1	nanoparticles					189:201	magnetic nanoparticles	180:201	magnetic nanoparticles (MNPs)	180:208	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	35	theme	alginate	161:168	arg1	Hydrogels					115:123	Hydrogels	115:123	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA)	115:173	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	0	36	theme	vinyl	5:9	arg1	Poly					0:3	Poly	0:3	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	0	36	theme	vinyl	5:9	arg1	alcohol					11:17	vinyl alcohol	5:17	vinyl alcohol	5:17	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	1	37	theme	solvent	227:233	arg1	casting					235:241	solvent casting	227:241	solvent casting	227:241	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	6	38	theme	PVA/SA-gMNP	1131:1141	arg1	coatings					1143:1150	PVA/SA-gMNP coatings	1131:1150	PVA/SA-gMNP coatings	1131:1150	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	5	39	with	PVA/SA-rMNP	912:922	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	0	40	theme	/sodium	19:25	arg1	composites					46:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites	0:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	7	41	theme	HT-22	1462:1466	arg1	cells					1468:1472	HT-22 cells	1462:1472	HT-22 cells	1462:1472	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	7	42	theme	surface	1410:1416	arg1	roughness					1418:1426	surface roughness	1410:1426	surface roughness	1410:1426	These findings showed that the orientation of magnetic domains led to an increase of surface roughness, which decreased the viability of HT-22 cells.					
36951357	0	43	dep	composites	46:55	arg1	microscopy					73:82	magnetic force microscopy	58:82	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	5	44	theme	hippocampal	1075:1085	arg1	cells					1093:1097	mouse hippocampal HT-22 cells	1069:1097	mouse hippocampal HT-22 cells	1069:1097	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	3	45	theme	nm	663:664	arg1	distance					632:639	The tip-surface distance	616:639	The tip-surface distance (lift distance) of 50 nm during the MFM analyses	616:688	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	3	45	theme	nm	663:664	arg1	distance					647:654	lift distance	642:654	lift distance	642:654	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	2	46	theme	Atomic	417:422	arg1	AFM					442:444	AFM	442:444	AFM	442:444	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	2	46	theme	Atomic	417:422	arg1	microscopy					430:439	Atomic force microscopy	417:439	Atomic force microscopy (AFM)	417:445	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	4	47	theme	isolated	877:884	arg1	MNPs					886:889	isolated MNPs	877:889	isolated MNPs	877:889	The magnetic signal stemming from clusters of MNPs were more easily identified than that from isolated MNPs.					
36951357	5	48	with	PVA	892:894	arg1	roughness					963:971	surface roughness	955:971	surface roughness	955:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	5	49	theme	PVA/SA-gMNP	929:939	arg1	coatings					941:948	PVA/SA-gMNP coatings	929:948	PVA/SA-gMNP coatings with surface roughness	929:971	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	5	50	theme	PVA	892:894	arg1	values					978:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	2	51	theme	polymer	586:592	arg1	matrix					594:599	the polymer matrix	582:599	the polymer matrix	582:599	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	0	52	theme	alginate/magnetite	27:44	arg1	composites					46:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites	0:55	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	5	53	theme	nm	992:993	arg1	values					978:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	4	54	theme	magnetic	787:794	arg1	signal					796:801	The magnetic signal	783:801	The magnetic signal stemming from clusters of MNPs	783:832	The magnetic signal stemming from clusters of MNPs were more easily identified than that from isolated MNPs.					
36951357	5	55	theme	SA	900:901	arg1	values					978:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values	892:983	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	8	56	theme	proliferation	1558:1570	arg1	necessary					1575:1583	necessary	1575:1583	necessary	1575:1583	Thus, these results might be interesting for situations, where the control of cell proliferation is necessary.					
36951357	8	56	theme	proliferation	1558:1570	arg1	control					1542:1548	the control	1538:1548	the control of cell proliferation	1538:1570	Thus, these results might be interesting for situations, where the control of cell proliferation is necessary.					
36951357	6	57	dep	control	1203:1209	arg1	comparison					1185:1194	comparison	1185:1194	comparison	1185:1194	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36951357	3	58	theme	domains	726:732	arg1	mapping					706:712	the mapping	702:712	the mapping of magnetic domains	702:732	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	2	59	used	used	499:502	arg2	techniques					483:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	2	60	theme	microscopy	466:475	arg1	techniques					483:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques	417:492	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	8	61	theme	cell	1553:1556	arg1	proliferation					1558:1570	cell proliferation	1553:1570	cell proliferation	1553:1570	Thus, these results might be interesting for situations, where the control of cell proliferation is necessary.					
36951357	5	62	theme	HT-22	1087:1091	arg1	cells					1093:1097	mouse hippocampal HT-22 cells	1069:1097	mouse hippocampal HT-22 cells	1069:1097	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	2	63	theme	force	460:464	arg1	microscopy					466:475	magnetic force microscopy	451:475	magnetic force microscopy (MFM)	451:481	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	2	63	theme	force	460:464	arg1	MFM					478:480	MFM	478:480	MFM	478:480	Atomic force microscopy (AFM) and magnetic force microscopy (MFM) techniques were used to evaluate the topography and to map the distribution of magnetic domains in the polymer matrix, respectively.					
36951357	1	64	theme	poly	128:131	arg1	SA					171:172	SA	171:172	SA	171:172	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	64	theme	poly	128:131	arg1	alginate					161:168	poly(vinyl alcohol) (PVA)/sodium alginate	128:168	poly(vinyl alcohol) (PVA)/sodium alginate (SA)	128:173	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	5	65	theme	cells	1093:1097	arg1	proliferation					1052:1064	the proliferation	1048:1064	the proliferation of mouse hippocampal HT-22 cells	1048:1097	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	3	66	theme	MFM	677:679	arg1	analyses					681:688	the MFM analyses	673:688	the MFM analyses	673:688	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	0	67	theme	magnetic	58:65	arg1	microscopy					73:82	magnetic force microscopy	58:82	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.	0:113	Poly(vinyl alcohol)/sodium alginate/magnetite composites: magnetic force microscopy for tracking magnetic domains.					
36951357	5	68	theme	mouse	1069:1073	arg1	cells					1093:1097	mouse hippocampal HT-22 cells	1069:1097	mouse hippocampal HT-22 cells	1069:1097	PVA and SA, PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings with surface roughness (Ra) values of 3.8 nm, 28.7 nm, and 49.8 nm, respectively, were tested for the proliferation of mouse hippocampal HT-22 cells.					
36951357	3	69	theme	magnetic	717:724	arg1	domains					726:732	magnetic domains	717:732	magnetic domains	717:732	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	1	70	theme	magnetic	180:187	arg1	MNPs					204:207	MNPs	204:207	MNPs	204:207	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	70	theme	magnetic	180:187	arg1	nanoparticles					189:201	magnetic nanoparticles	180:201	magnetic nanoparticles (MNPs)	180:208	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	71	theme	vinyl	133:137	arg1	poly					128:131	poly	128:131	poly(vinyl alcohol) (PVA)/sodium alginate (SA)	128:173	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	1	71	theme	vinyl	133:137	arg1	alcohol					139:145	vinyl alcohol	133:145	vinyl alcohol	133:145	Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence and in the presence of magnets, in order to obtain MNPs distributed randomly (PVA/SA-rMNP) and magnetically oriented MNPs (PVA/SA-gMNP) in the polymer matrix.					
36951357	3	72	theme	der	750:752	arg1	forces					760:765	the van der Waals forces	742:765	the van der Waals forces	742:765	The tip-surface distance (lift distance) of 50 nm during the MFM analyses facilitated the mapping of magnetic domains because the van der Waals forces were minimized.					
36951357	6	73	theme	viability	1167:1175	arg1	%					1180:1180	cell viability >70%	1162:1180	cell viability >70%	1162:1180	While PVA/SA, PVA/SA-rMNP, and PVA/SA-gMNP coatings preserved cell viability >70% in comparison to the control (plastic plate) over 48 h, cell proliferation tended to decrease on surfaces with higher Ra values (PVA/SA-gMNP).					
36669630	12	0	theme	Hg	1421:1422	arg1	removal					1410:1416	the removal	1406:1416	the removal of Hg(II) from wastewater	1406:1442	Hence, this adsorbent would be promising for the removal of Hg(II) from wastewater.					
36669630	3	1	theme	TGA	462:464	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	1	2	theme	novel	127:131	arg1	UNCS					172:175	UNCS	172:175	UNCS	172:175	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	2	theme	novel	127:131	arg1	chitosan					142:149	a novel modified chitosan composite adsorbent	125:169	a novel modified chitosan composite adsorbent (UNCS)	125:176	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	5	3	theme	kinetic	680:686	arg1	model					688:692	the pseudo-second-order kinetic model	656:692	the pseudo-second-order kinetic model	656:692	The kinetic studies indicated that the adsorption process followed the pseudo-second-order kinetic model and the adsorption equilibrium could be reached within 2 h.					
36669630	7	4	theme	homogeneous	919:929	arg1	adsorption					931:940	the homogeneous adsorption	915:940	the homogeneous adsorption on the surface of the adsorbent	915:972	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	5	5	theme	kinetic	593:599	arg1	studies					601:607	The kinetic studies	589:607	The kinetic studies	589:607	The kinetic studies indicated that the adsorption process followed the pseudo-second-order kinetic model and the adsorption equilibrium could be reached within 2 h.					
36669630	9	6	theme	adsorption	1171:1180	arg1	process					1182:1188	the adsorption process	1167:1188	the adsorption process	1167:1188	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	1	7	theme	metal	228:232	arg1	MOFs					254:257	MOFs	254:257	MOFs	254:257	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	7	theme	metal	228:232	arg1	frameworks					242:251	metal organic frameworks	228:251	metal organic frameworks (MOFs)	228:258	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	0	8	theme	Hg	91:92	arg1	adsorption					98:107	Hg(II) adsorption	91:107	Hg(II) adsorption	91:107	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	9	9	theme	process	1182:1188	arg1	nature					1135:1140	spontaneous nature	1123:1140	spontaneous nature	1123:1140	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	9	9	theme	process	1182:1188	arg1	nature					1157:1162	exothermic nature	1146:1162	exothermic nature	1146:1162	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	7	10	theme	isothermal	823:832	arg1	studies					834:840	Adsorption isothermal studies	812:840	Adsorption isothermal studies	812:840	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	1	11	theme	organic	234:240	arg1	MOFs					254:257	MOFs	254:257	MOFs	254:257	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	11	theme	organic	234:240	arg1	frameworks					242:251	metal organic frameworks	228:251	metal organic frameworks (MOFs)	228:258	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	11	12	theme	adsorption-desorption	1264:1284	arg1	experiments					1293:1303	The adsorption-desorption cycled experiments	1260:1303	The adsorption-desorption cycled experiments	1260:1303	The adsorption-desorption cycled experiments indicated the appropriate reusability of the adsorbent.					
36669630	3	13	theme	zeta	475:478	arg1	potential					480:488	zeta potential	475:488	zeta potential	475:488	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	9	14	dep	nature	1135:1140	arg1	the					1119:1121	the	1119:1121	the	1119:1121	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	1	15	theme	modified	133:140	arg1	UNCS					172:175	UNCS	172:175	UNCS	172:175	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	15	theme	modified	133:140	arg1	chitosan					142:149	a novel modified chitosan composite adsorbent	125:169	a novel modified chitosan composite adsorbent (UNCS)	125:176	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	3	16	dep	structure	381:389	arg1	The					377:379	The	377:379	The	377:379	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	3	17	theme	potential	480:488	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	5	18	theme	adsorption	702:711	arg1	equilibrium					713:723	the adsorption equilibrium	698:723	the adsorption equilibrium	698:723	The kinetic studies indicated that the adsorption process followed the pseudo-second-order kinetic model and the adsorption equilibrium could be reached within 2 h.					
36669630	7	19	theme	Adsorption	812:821	arg1	studies					834:840	Adsorption isothermal studies	812:840	Adsorption isothermal studies	812:840	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	1	20	theme	composite	151:159	arg1	UNCS					172:175	UNCS	172:175	UNCS	172:175	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	20	theme	composite	151:159	arg1	chitosan					142:149	a novel modified chitosan composite adsorbent	125:169	a novel modified chitosan composite adsorbent (UNCS)	125:176	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	11	21	theme	appropriate	1319:1329	arg1	reusability					1331:1341	the appropriate reusability	1315:1341	the appropriate reusability of the adsorbent	1315:1358	The adsorption-desorption cycled experiments indicated the appropriate reusability of the adsorbent.					
36669630	8	22	theme	Langmuir	1041:1048	arg1	model					1050:1054	Langmuir model	1041:1054	Langmuir model	1041:1054	The adsorbent exhibited high uptake and the maximum capacity from Langmuir model could reach 896.8 mg g-1 at pH 6.					
36669630	8	23	theme	high	999:1002	arg1	uptake					1004:1009	high uptake	999:1009	high uptake	999:1009	The adsorbent exhibited high uptake and the maximum capacity from Langmuir model could reach 896.8 mg g-1 at pH 6.					
36669630	1	24	theme	adsorbent	161:169	arg1	UNCS					172:175	UNCS	172:175	UNCS	172:175	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	1	24	theme	adsorbent	161:169	arg1	chitosan					142:149	a novel modified chitosan composite adsorbent	125:169	a novel modified chitosan composite adsorbent (UNCS)	125:176	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	0	25	theme	organic	21:27	arg1	frameworks					29:38	metal organic frameworks	15:38	metal organic frameworks	15:38	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	3	26	theme	FT-IR	445:449	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	0	27	theme	metal	15:19	arg1	frameworks					29:38	metal organic frameworks	15:38	metal organic frameworks	15:38	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	4	28	theme	variables	521:529	arg1	Effects					500:506	Effects	500:506	Effects of different variables for adsorption of Hg(II) on this adsorbent	500:572	Effects of different variables for adsorption of Hg(II) on this adsorbent were explored.					
36669630	9	29	theme	Thermodynamic	1090:1102	arg1	studies					1104:1110	Thermodynamic studies	1090:1110	Thermodynamic studies	1090:1110	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	2	30	theme	prepared	339:346	arg1	conditions					348:357	the prepared conditions	335:357	the prepared conditions	335:357	The influence of the prepared conditions was investigated.					
36669630	4	31	theme	different	511:519	arg1	variables					521:529	different variables	511:529	different variables for adsorption of Hg(II)	511:554	Effects of different variables for adsorption of Hg(II) on this adsorbent were explored.					
36669630	2	32	theme	conditions	348:357	arg1	influence					322:330	The influence	318:330	The influence of the prepared conditions	318:357	The influence of the prepared conditions was investigated.					
36669630	0	33	theme	frameworks	29:38	arg1	Preparation					0:10	Preparation	0:10	Preparation of metal organic frameworks	0:38	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	1	34	theme	material	260:267	arg1	UiO-66-NH2					269:278	material UiO-66-NH2	260:278	material UiO-66-NH2	260:278	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	5	35	theme	pseudo-second-order	660:678	arg1	model					688:692	the pseudo-second-order kinetic model	656:692	the pseudo-second-order kinetic model	656:692	The kinetic studies indicated that the adsorption process followed the pseudo-second-order kinetic model and the adsorption equilibrium could be reached within 2 h.					
36669630	12	36	from	wastewater	1433:1442	arg1	removal					1410:1416	the removal	1406:1416	the removal of Hg(II) from wastewater	1406:1442	Hence, this adsorbent would be promising for the removal of Hg(II) from wastewater.					
36669630	8	37	from	model	1050:1054	arg1	capacity					1027:1034	the maximum capacity	1015:1034	the maximum capacity from Langmuir model	1015:1054	The adsorbent exhibited high uptake and the maximum capacity from Langmuir model could reach 896.8 mg g-1 at pH 6.					
36669630	3	38	theme	composite	413:421	arg1	structure					381:389	structure	381:389	structure	381:389	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	3	38	theme	composite	413:421	arg1	morphology					395:404	morphology	395:404	morphology	395:404	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	3	39	theme	SEM	457:459	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	0	40	theme	chitosan	49:56	arg1	composite					58:66	chitosan composite	49:66	chitosan composite	49:66	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	11	41	theme	cycled	1286:1291	arg1	experiments					1293:1303	The adsorption-desorption cycled experiments	1260:1303	The adsorption-desorption cycled experiments	1260:1303	The adsorption-desorption cycled experiments indicated the appropriate reusability of the adsorbent.					
36669630	9	42	theme	spontaneous	1123:1133	arg1	nature					1135:1140	spontaneous nature	1123:1140	spontaneous nature	1123:1140	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	8	43	theme	maximum	1019:1025	arg1	capacity					1027:1034	the maximum capacity	1015:1034	the maximum capacity from Langmuir model	1015:1054	The adsorbent exhibited high uptake and the maximum capacity from Langmuir model could reach 896.8 mg g-1 at pH 6.					
36669630	7	44	theme	isotherm	890:897	arg1	model					899:903	Langmuir isotherm model	881:903	Langmuir isotherm model	881:903	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	10	45	from	removal	1209:1215	arg1	UNCS					1230:1233	UNCS	1230:1233	UNCS	1230:1233	Additionally, the removal of Hg(II) on UNCS could achieve over 90 %.					
36669630	6	46	theme	chemical	794:801	arg1	process					803:809	chemical process	794:809	chemical process	794:809	The adsorption was mainly controlled by chemical process.					
36669630	10	47	attach	removal	1209:1215	arg2	II					1223:1224	II	1223:1224	II	1223:1224	Additionally, the removal of Hg(II) on UNCS could achieve over 90 %.					
36669630	10	47	attach	removal	1209:1215	arg2	Hg					1220:1221	Hg	1220:1221	Hg(II)	1220:1225	Additionally, the removal of Hg(II) on UNCS could achieve over 90 %.					
36669630	10	47	attach	removal	1209:1215	arg3	UNCS					1230:1233	UNCS	1230:1233	UNCS	1230:1233	Additionally, the removal of Hg(II) on UNCS could achieve over 90 %.					
36669630	3	48	theme	XRD	452:454	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	5	49	theme	adsorption	628:637	arg1	process					639:645	the adsorption process	624:645	the adsorption process	624:645	The kinetic studies indicated that the adsorption process followed the pseudo-second-order kinetic model and the adsorption equilibrium could be reached within 2 h.					
36669630	1	50	dep	chitosan	215:222	arg1	UiO-66-NH2					269:278	material UiO-66-NH2	260:278	material UiO-66-NH2	260:278	In this study, a novel modified chitosan composite adsorbent (UNCS) was prepared by crosslinking between chitosan and metal organic frameworks (MOFs) material UiO-66-NH2 using epichlorohydrin as crosslinker.					
36669630	7	51	theme	adsorbent	964:972	arg1	surface					949:955	the surface	945:955	the surface of the adsorbent	945:972	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	10	52	theme	Hg	1220:1221	arg1	removal					1209:1215	the removal	1205:1215	the removal of Hg(II) on UNCS	1205:1233	Additionally, the removal of Hg(II) on UNCS could achieve over 90 %.					
36669630	0	53	theme	high	73:76	arg1	capacity					78:85	high capacity	73:85	high capacity for Hg(II) adsorption	73:107	Preparation of metal organic frameworks modified chitosan composite with high capacity for Hg(II) adsorption.					
36669630	9	54	theme	exothermic	1146:1155	arg1	nature					1157:1162	exothermic nature	1146:1162	exothermic nature	1146:1162	Thermodynamic studies showed the spontaneous nature and exothermic nature of the adsorption process.					
36669630	3	55	theme	BET	467:469	arg1	analysis					490:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	FT-IR, XRD, SEM, TGA, BET and zeta potential analysis	445:497	The structure and morphology of the composite were characterized by FT-IR, XRD, SEM, TGA, BET and zeta potential analysis.					
36669630	7	56	theme	Langmuir	881:888	arg1	model					899:903	Langmuir isotherm model	881:903	Langmuir isotherm model	881:903	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
36669630	4	57	theme	Hg	549:550	arg1	adsorption					535:544	adsorption	535:544	adsorption of Hg(II)	535:554	Effects of different variables for adsorption of Hg(II) on this adsorbent were explored.					
36669630	11	58	theme	adsorbent	1350:1358	arg1	reusability					1331:1341	the appropriate reusability	1315:1341	the appropriate reusability of the adsorbent	1315:1358	The adsorption-desorption cycled experiments indicated the appropriate reusability of the adsorbent.					
36669630	4	59	from	Effects	500:506	arg1	adsorbent					564:572	adsorbent	564:572	adsorbent	564:572	Effects of different variables for adsorption of Hg(II) on this adsorbent were explored.					
36669630	7	60	from	adsorption	931:940	arg1	surface					949:955	the surface	945:955	the surface of the adsorbent	945:972	Adsorption isothermal studies illustrated that the adsorption fitted Langmuir isotherm model, implying the homogeneous adsorption on the surface of the adsorbent.					
35965210	10	0	theme	CHO/Aleo	1789:1796	arg1	group					1802:1806	the CHO/Aleo gel group	1785:1806	the CHO/Aleo gel group	1785:1806	Epidermal thickness was also significantly thicker in the CHO/Aleo gel group than others (p < 0.05).					
35965210	1	1	theme	wound-healing	264:276	arg1	process					278:284	the wound-healing process	260:284	the wound-healing process	260:284	OBJECTIVE Chitosan-based hydrogels as wound dressings are expected to improve the efficiency of the wound-healing process.					
35965210	9	2	theme	inflammatory	1630:1641	arg1	response					1643:1650	inflammatory response	1630:1650	inflammatory response	1630:1650	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	4	3	theme	rat	886:888	arg1	models					890:895	rat models	886:895	rat models	886:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	6	4	theme	tissue	1253:1258	arg1	formation					1260:1268	fibrotic tissue formation	1244:1268	fibrotic tissue formation	1244:1268	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	11	5	theme	wound-healing	2082:2094	arg1	procedures					2096:2105	the wound-healing procedures	2078:2105	the wound-healing procedures	2078:2105	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	2	6	theme	Aloe	329:332	arg1	vera					334:337	Aloe vera	329:337	Aloe vera	329:337	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	1	7	theme	wound	202:206	arg1	dressings					208:216	wound dressings	202:216	wound dressings	202:216	OBJECTIVE Chitosan-based hydrogels as wound dressings are expected to improve the efficiency of the wound-healing process.					
35965210	4	8	theme	MATERIALS	676:684	arg1	hydrogel					702:709	MATERIALS AND METHODS CHO hydrogel	676:709	MATERIALS AND METHODS CHO hydrogel with Aloe	676:719	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	0	9	theme	full	129:132	arg1	model					150:154	full thickness wound model	129:154	full thickness wound model of rat	129:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	3	10	theme	CHO/Aloe	598:605	arg1	hydrogel					607:614	improved CHO/Aloe hydrogel	589:614	improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model	589:673	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	4	11	theme	METHODS	690:696	arg1	hydrogel					702:709	MATERIALS AND METHODS CHO hydrogel	676:709	MATERIALS AND METHODS CHO hydrogel with Aloe	676:719	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	8	12	with	gel	1495:1497	arg1	tension					1523:1529	the highest tissue tension	1504:1529	the highest tissue tension	1504:1529	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	0	13	theme	wound	144:148	arg1	model					150:154	full thickness wound model	129:154	full thickness wound model of rat	129:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	4	14	from	wounds	876:881	arg1	terms					772:776	terms	772:776	terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	772:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	8	15	theme	highest	1508:1514	arg1	tension					1523:1529	the highest tissue tension	1504:1529	the highest tissue tension	1504:1529	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	11	16	theme	effective	1877:1885	arg1	system					1909:1914	the effective topical drug-delivery system	1873:1914	the effective topical drug-delivery system	1873:1914	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	8	17	theme	best	1446:1449	arg1	healing					1451:1457	the best healing	1442:1457	the best healing effect	1442:1464	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	6	18	theme	Histological	1074:1085	arg1	evaluation					1087:1096	Histological evaluation	1074:1096	Histological evaluation	1074:1096	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	0	19	from	improvement	90:100	arg1	model					150:154	full thickness wound model	129:154	full thickness wound model of rat	129:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	7	20	theme	wound-healing	1321:1333	arg1	rate					1335:1338	a significantly higher wound-healing rate	1298:1338	a significantly higher wound-healing rate of the CHO/Aleo group	1298:1360	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	9	21	theme	Histological	1570:1581	arg1	findings					1583:1590	Histological findings	1570:1590	Histological findings	1570:1590	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	9	22	from	difference	1616:1625	arg1	response					1643:1650	inflammatory response	1630:1650	inflammatory response	1630:1650	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	11	23	dep	improved	1864:1871	arg1	an					1861:1862	an	1861:1862	an	1861:1862	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	1	24	theme	OBJECTIVE	164:172	arg1	hydrogels					189:197	OBJECTIVE Chitosan-based hydrogels	164:197	OBJECTIVE Chitosan-based hydrogels as wound dressings	164:216	OBJECTIVE Chitosan-based hydrogels as wound dressings are expected to improve the efficiency of the wound-healing process.					
35965210	0	25	from	Evaluation	0:9	arg1	improvement					90:100	the improvement	86:100	the improvement of re-epithelialization in full thickness wound model of rat	86:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	4	26	theme	antibacterial	792:804	arg1	activity					806:813	antibacterial activity	792:813	antibacterial activity	792:813	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	9	27	theme	significant	1604:1614	arg1	difference					1616:1625	a significant difference	1602:1625	a significant difference in inflammatory response between control and treatment groups	1602:1687	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	0	28	theme	re-epithelialization	105:124	arg1	improvement					90:100	the improvement	86:100	the improvement of re-epithelialization in full thickness wound model of rat	86:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	4	29	from	viscosity	781:789	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	0	30	theme	hydrogel	74:81	arg1	efficiency					28:37	wound-healing efficiency	14:37	wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel	14:81	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	2	31	theme	wound-healing	403:415	arg1	process					417:423	the wound-healing process	399:423	the wound-healing process	399:423	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	4	32	from	terms	772:776	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	5	33	theme	wound	1001:1005	arg1	closure					1007:1013	total wound closure	995:1013	total wound closure	995:1013	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	4	34	theme	viscosity	781:789	arg1	terms					772:776	terms	772:776	terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	772:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	2	35	theme	wide	454:457	arg1	spectrum					459:466	a wide spectrum	452:466	a wide spectrum of microbes	452:478	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	0	36	theme	wound-healing	14:26	arg1	efficiency					28:37	wound-healing efficiency	14:37	wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel	14:81	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	9	37	theme	control	1660:1666	arg1	groups					1682:1687	control and treatment groups	1660:1687	groups	1682:1687	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	1	38	theme	Chitosan-based	174:187	arg1	hydrogels					189:197	OBJECTIVE Chitosan-based hydrogels	164:197	OBJECTIVE Chitosan-based hydrogels as wound dressings	164:216	OBJECTIVE Chitosan-based hydrogels as wound dressings are expected to improve the efficiency of the wound-healing process.					
35965210	9	39	theme	treatment	1672:1680	arg1	groups					1682:1687	control and treatment groups	1660:1687	groups	1682:1687	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	7	40	dep	RESULTS	1271:1277	arg1	showed					1291:1296	showed	1291:1296	showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05)	1291:1411	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	0	41	theme	vera	69:72	arg1	hydrogel					74:81	a functional Chitosan/Aloe vera hydrogel	42:81	a functional Chitosan/Aloe vera hydrogel	42:81	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	0	42	theme	functional	44:53	arg1	hydrogel					74:81	a functional Chitosan/Aloe vera hydrogel	42:81	a functional Chitosan/Aloe vera hydrogel	42:81	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	7	43	theme	other	1374:1378	arg1	groups					1380:1385	other groups	1374:1385	other groups	1374:1385	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	4	44	theme	ints	820:823	arg1	efficiency					847:856	ints In-vivo wound-healing efficiency	820:856	ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	820:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	4	45	theme	efficiency	847:856	arg1	terms					772:776	terms	772:776	terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	772:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	2	46	theme	biopolymeric	343:354	arg1	hydrogels					356:364	Aloe vera and biopolymeric hydrogels	329:364	Aloe vera and biopolymeric hydrogels	329:364	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	5	47	theme	epiderm	1045:1051	arg1	thickness					1053:1061	the epiderm thickness	1041:1061	the epiderm thickness of wounds	1041:1071	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	6	48	theme	inflammatory	1187:1198	arg1	response					1200:1207	inflammatory response	1187:1207	inflammatory response	1187:1207	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	4	49	theme	wound-healing	833:845	arg1	efficiency					847:856	ints In-vivo wound-healing efficiency	820:856	ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	820:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	3	50	theme	present	544:550	arg1	study					552:556	the present study	540:556	the present study	540:556	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	6	51	theme	tissue	1222:1227	arg1	formation					1229:1237	granulation tissue formation	1210:1237	granulation tissue formation	1210:1237	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	9	52	theme	treatment	1709:1717	arg1	days					1701:1704	three days	1695:1704	three days of treatment (p < 0.05)	1695:1728	Histological findings indicated a significant difference in inflammatory response between control and treatment groups after three days of treatment (p < 0.05).					
35965210	7	53	theme	CHO/Aleo	1347:1354	arg1	group					1356:1360	the CHO/Aleo group	1343:1360	the CHO/Aleo group	1343:1360	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	10	54	theme	gel	1798:1800	arg1	group					1802:1806	the CHO/Aleo gel group	1785:1806	the CHO/Aleo gel group	1785:1806	Epidermal thickness was also significantly thicker in the CHO/Aleo gel group than others (p < 0.05).					
35965210	2	55	theme	composite	306:314	arg1	structure					316:324	the composite structure	302:324	the composite structure of Aloe vera and biopolymeric hydrogels	302:364	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	1	56	theme	process	278:284	arg1	efficiency					246:255	the efficiency	242:255	the efficiency of the wound-healing process	242:284	OBJECTIVE Chitosan-based hydrogels as wound dressings are expected to improve the efficiency of the wound-healing process.					
35965210	2	57	theme	vera	334:337	arg1	hydrogels					356:364	Aloe vera and biopolymeric hydrogels	329:364	Aloe vera and biopolymeric hydrogels	329:364	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	5	58	theme	Physical	898:905	arg1	examination					907:917	Physical examination	898:917	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel	898:966	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	6	59	theme	fibrotic	1244:1251	arg1	formation					1260:1268	fibrotic tissue formation	1244:1268	fibrotic tissue formation	1244:1268	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	4	60	theme	CHO	698:700	arg1	hydrogel					702:709	MATERIALS AND METHODS CHO hydrogel	676:709	MATERIALS AND METHODS CHO hydrogel with Aloe	676:719	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	11	61	with	hydrogel	1928:1935	arg1	potential					1946:1954	the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures	1942:2105	the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures	1942:2105	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	3	62	theme	hydrogel	607:614	arg1	development					574:584	development	574:584	development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model	574:673	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	4	63	theme	models	890:895	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	0	64	theme	thickness	134:142	arg1	model					150:154	full thickness wound model	129:154	full thickness wound model of rat	129:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	3	65	theme	improved	589:596	arg1	hydrogel					607:614	improved CHO/Aloe hydrogel	589:614	improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model	589:673	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	8	66	located	observed	1470:1477	arg2	effect					1459:1464	the best healing effect	1442:1464	the best healing effect	1442:1464	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	8	66	located	observed	1470:1477	arg1	gel					1495:1497	the CHO/Aleo gel	1482:1497	the CHO/Aleo gel with the highest tissue tension	1482:1529	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	5	67	theme	hydrogel	959:966	arg1	efficiency					936:945	wound-healing efficiency	922:945	wound-healing efficiency of CHO/Aleo hydrogel	922:966	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	3	68	theme	wound-healing	634:646	arg1	process					648:654	the wound-healing process	630:654	the wound-healing process	630:654	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	5	69	theme	wound-healing	922:934	arg1	efficiency					936:945	wound-healing efficiency	922:945	wound-healing efficiency of CHO/Aleo hydrogel	922:966	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	8	70	theme	tissue	1516:1521	arg1	tension					1523:1529	the highest tissue tension	1504:1529	the highest tissue tension	1504:1529	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	0	71	theme	rat	159:161	arg1	model					150:154	full thickness wound model	129:154	full thickness wound model of rat	129:161	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	11	72	theme	topical	1887:1893	arg1	system					1909:1914	the effective topical drug-delivery system	1873:1914	the effective topical drug-delivery system	1873:1914	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	11	73	dep	CONCLUSION	1832:1841	arg1	improved					1864:1871	improved	1864:1871	an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures	1861:2105	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	3	74	theme	animal	662:667	arg1	model					669:673	an animal model	659:673	an animal model	659:673	Therefore, the present study investigates to development of improved CHO/Aloe hydrogel for improving the wound-healing process in an animal model.					
35965210	4	75	from	efficiency	847:856	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	8	76	theme	other	1545:1549	arg1	p < 0.05					1559:1566	p < 0.05	1559:1566	p < 0.05	1559:1566	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	8	76	theme	other	1545:1549	arg1	groups					1551:1556	other groups	1545:1556	other groups (p < 0.05)	1545:1567	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	7	77	theme	higher	1314:1319	arg1	rate					1335:1338	a significantly higher wound-healing rate	1298:1338	a significantly higher wound-healing rate of the CHO/Aleo group	1298:1360	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	5	78	theme	efficiency	936:945	arg1	examination					907:917	Physical examination	898:917	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel	898:966	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	5	79	theme	CHO/Aleo	950:957	arg1	hydrogel					959:966	CHO/Aleo hydrogel	950:966	CHO/Aleo hydrogel	950:966	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	11	80	theme	present	1847:1853	arg1	study					1855:1859	The present study	1843:1859	The present study	1843:1859	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	4	81	from	activity	806:813	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	5	82	theme	recovery	1016:1023	arg1	percentage					1025:1034	recovery percentage	1016:1034	recovery percentage	1016:1034	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	2	83	theme	structure	316:324	arg1	Fabrication					287:297	Fabrication	287:297	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels	287:364	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	4	84	theme	activity	806:813	arg1	terms					772:776	terms	772:776	terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	772:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	5	85	theme	total	995:999	arg1	closure					1007:1013	total wound closure	995:1013	total wound closure	995:1013	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	6	86	theme	eosin	1134:1138	arg1	staining					1140:1147	hematoxylin and eosin staining	1118:1147	hematoxylin and eosin staining to evaluate the re-epithelialization	1118:1184	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	2	87	theme	microbes	471:478	arg1	spectrum					459:466	a wide spectrum	452:466	a wide spectrum of microbes	452:478	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	8	88	theme	treatment	1431:1439	arg1	days					1423:1426	14 days	1420:1426	14 days of treatment	1420:1439	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	0	89	theme	efficiency	28:37	arg1	Evaluation					0:9	Evaluation	0:9	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.	0:162	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	6	90	theme	hematoxylin	1118:1128	arg1	staining					1140:1147	hematoxylin and eosin staining	1118:1147	hematoxylin and eosin staining to evaluate the re-epithelialization	1118:1184	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	5	91	theme	wounds	1066:1071	arg1	closure					1007:1013	total wound closure	995:1013	total wound closure	995:1013	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	5	91	theme	wounds	1066:1071	arg1	thickness					1053:1061	the epiderm thickness	1041:1061	the epiderm thickness of wounds	1041:1071	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	5	91	theme	wounds	1066:1071	arg1	percentage					1025:1034	recovery percentage	1016:1034	recovery percentage	1016:1034	Physical examination of wound-healing efficiency of CHO/Aleo hydrogel was evaluated by analyzing total wound closure, recovery percentage, and the epiderm thickness of wounds.					
35965210	2	92	theme	cell	494:497	arg1	adhesion					499:506	cell adhesion	494:506	cell adhesion	494:506	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	4	93	with	hydrogel	702:709	arg1	Aloe					716:719	Aloe	716:719	Aloe	716:719	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	8	94	theme	healing	1451:1457	arg1	effect					1459:1464	the best healing effect	1442:1464	the best healing effect	1442:1464	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35965210	10	95	theme	Epidermal	1731:1739	arg1	thickness					1741:1749	Epidermal thickness	1731:1749	Epidermal thickness	1731:1749	Epidermal thickness was also significantly thicker in the CHO/Aleo gel group than others (p < 0.05).					
35965210	0	96	theme	Chitosan/Aloe	55:67	arg1	hydrogel					74:81	a functional Chitosan/Aloe vera hydrogel	42:81	a functional Chitosan/Aloe vera hydrogel	42:81	Evaluation of wound-healing efficiency of a functional Chitosan/Aloe vera hydrogel on the improvement of re-epithelialization in full thickness wound model of rat.					
35965210	11	97	theme	drug-delivery	1895:1907	arg1	system					1909:1914	the effective topical drug-delivery system	1873:1914	the effective topical drug-delivery system	1873:1914	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	6	98	theme	granulation	1210:1220	arg1	formation					1229:1237	granulation tissue formation	1210:1237	granulation tissue formation	1210:1237	Histological evaluation was performed using hematoxylin and eosin staining to evaluate the re-epithelialization, inflammatory response, granulation tissue formation, and fibrotic tissue formation.					
35965210	4	99	theme	full-thickness	861:874	arg1	wounds					876:881	full-thickness wounds	861:881	full-thickness wounds of rat models	861:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	2	100	theme	hydrogels	356:364	arg1	structure					316:324	the composite structure	302:324	the composite structure of Aloe vera and biopolymeric hydrogels	302:364	Fabrication of the composite structure of Aloe vera and biopolymeric hydrogels has been demonstrated to promote the wound-healing process through protection against a wide spectrum of microbes, and enhanced cell adhesion and differentiation.					
35965210	4	101	theme	In-vivo	825:831	arg1	efficiency					847:856	ints In-vivo wound-healing efficiency	820:856	ints In-vivo wound-healing efficiency in full-thickness wounds of rat models	820:895	MATERIALS AND METHODS CHO hydrogel with Aloe was prepared, and its properties were evaluated in terms of viscosity, antibacterial activity, and ints In-vivo wound-healing efficiency in full-thickness wounds of rat models.					
35965210	7	102	theme	group	1356:1360	arg1	rate					1335:1338	a significantly higher wound-healing rate	1298:1338	a significantly higher wound-healing rate of the CHO/Aleo group	1298:1360	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	7	103	dep	showed	1291:1296	arg1	compared					1362:1369	compared	1362:1369	showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05)	1291:1411	RESULTS The results showed a significantly higher wound-healing rate of the CHO/Aleo group compared to other groups at 3,7,14 days (p < 0.05).					
35965210	11	104	theme	CHO/Aloe	1919:1926	arg1	hydrogel					1928:1935	CHO/Aloe hydrogel	1919:1935	CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures	1919:2105	CONCLUSION The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures.					
35965210	8	105	theme	CHO/Aleo	1486:1493	arg1	gel					1495:1497	the CHO/Aleo gel	1482:1497	the CHO/Aleo gel with the highest tissue tension	1482:1529	After 14 days of treatment, the best healing effect was observed in the CHO/Aleo gel with the highest tissue tension compared with other groups (p < 0.05).					
35341871	0	0	theme	formaldehyde	83:94	arg1	oxidation					96:104	catalytic formaldehyde oxidation	73:104	catalytic formaldehyde oxidation	73:104	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	6	1	theme	surface	1709:1715	arg1	intermediates					1717:1729	the surface intermediates	1705:1729	the surface intermediates of the spent materials	1705:1752	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	3	2	theme	control	851:857	arg1	samples					859:865	the control samples	847:865	the control samples	847:865	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	0	3	theme	catalytic	73:81	arg1	oxidation					96:104	catalytic formaldehyde oxidation	73:104	catalytic formaldehyde oxidation	73:104	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	5	4	theme	viable	1446:1451	arg1	irradiation					1462:1472	the viable sunlight irradiation	1442:1472	the viable sunlight irradiation	1442:1472	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35341871	6	5	theme	reaction	1597:1604	arg1	pathways					1606:1613	reaction pathways	1597:1613	reaction pathways	1597:1613	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	4	6	theme	strong	1024:1029	arg1	converter					1255:1263	a much better HCHO-to-CO2 converter	1229:1263	a much better HCHO-to-CO2 converter	1229:1263	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	6	theme	strong	1024:1029	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	6	theme	strong	1024:1029	arg1	interaction					1031:1041	the strong interaction	1020:1041	the strong interaction between the dispersed MnO2 particles	1020:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	7	theme	MnO2	1065:1068	arg1	particles					1070:1078	the dispersed MnO2 particles	1051:1078	the dispersed MnO2 particles	1051:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	8	theme	physicochemical	535:549	arg1	properties					551:560	their physicochemical properties	529:560	their physicochemical properties	529:560	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	4	9	theme	repeated	1316:1323	arg1	cycles					1325:1330	repeated cycles	1316:1330	repeated cycles of formaldehyde oxidation	1316:1356	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	5	10	theme	sunlight	1453:1460	arg1	irradiation					1462:1472	the viable sunlight irradiation	1442:1472	the viable sunlight irradiation	1442:1472	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35341871	2	11	theme	3D	328:329	arg1	MnO2					353:356	MnO2	353:356	MnO2 (AM-3D)	353:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	11	theme	3D	328:329	arg1	agar					344:347	agar	344:347	agar	344:347	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	11	theme	3D	328:329	arg1	composite					331:339	The 3D composite	324:339	The 3D composite of agar and MnO2 (AM-3D)	324:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	1	12	theme	benign	304:309	arg1	powder					316:321	environmentally benign agar powder	288:321	environmentally benign agar powder	288:321	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	4	13	theme	3D	898:899	arg1	scaffold					906:913	the porous 3D agar scaffold	887:913	the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	887:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	3	14	theme	oxidation	694:702	arg1	test					673:676	the single test	662:676	the single test of formaldehyde oxidation	662:702	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	4	15	theme	formaldehyde	978:989	arg1	reduction					1005:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	16	theme	AM-3D	1209:1213	arg1	composite					1215:1223	the AM-3D composite	1205:1223	the AM-3D composite	1205:1223	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	16	theme	AM-3D	1209:1213	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	5	17	theme	AM-3D	1520:1524	arg1	catalyst					1526:1533	the used AM-3D catalyst	1511:1533	the used AM-3D catalyst	1511:1533	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35341871	1	18	theme	agar	311:314	arg1	powder					316:321	environmentally benign agar powder	288:321	environmentally benign agar powder	288:321	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	6	19	from	investigations	1687:1700	arg1	intermediates					1717:1729	the surface intermediates	1705:1729	the surface intermediates of the spent materials	1705:1752	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	3	20	dep	%	738:738	arg1	percentage					754:763	-67.0% removal percentage	739:763	62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples	734:865	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	6	21	theme	ion	1667:1669	arg1	investigations					1687:1700	the infrared spectroscopic and ion chromatographic investigations	1636:1700	investigations	1687:1700	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	1	22	theme	freestanding	174:185	arg1	assembly					199:206	a freestanding ultra-light assembly	172:206	a freestanding ultra-light assembly	172:206	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	4	23	theme	advantageous	1289:1300	arg1	stability					1302:1310	much more advantageous stability	1279:1310	much more advantageous stability for repeated cycles of formaldehyde oxidation	1279:1356	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	24	theme	3D-structured	478:490	arg1	agar					492:495	the 3D-structured agar	474:495	the 3D-structured agar for formaldehyde oxidation	474:522	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	4	25	theme	reactive	1135:1142	arg1	species					1151:1157	reactive oxygen species	1135:1157	reactive oxygen species	1135:1157	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	26	theme	MnO2	353:356	arg1	MnO2					353:356	MnO2	353:356	MnO2 (AM-3D)	353:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	26	theme	MnO2	353:356	arg1	agar					344:347	agar	344:347	agar	344:347	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	26	theme	MnO2	353:356	arg1	composite					331:339	The 3D composite	324:339	The 3D composite of agar and MnO2 (AM-3D)	324:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	1	27	theme	ultra-light	187:197	arg1	assembly					199:206	a freestanding ultra-light assembly	172:206	a freestanding ultra-light assembly	172:206	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	0	28	theme	3D	12:13	arg1	network					25:31	3D MnO2-agar network	12:31	3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation	12:104	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	3	29	theme	formaldehyde	681:692	arg1	oxidation					694:702	formaldehyde oxidation	681:702	formaldehyde oxidation	681:702	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	2	30	theme	N2	612:613	arg1	adsorption					615:624	isothermal N2 adsorption	601:624	isothermal N2 adsorption	601:624	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	6	31	theme	materials	1744:1752	arg1	intermediates					1717:1729	the surface intermediates	1705:1729	the surface intermediates of the spent materials	1705:1752	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	4	32	theme	agar	901:904	arg1	scaffold					906:913	the porous 3D agar scaffold	887:913	the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	887:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	6	33	theme	chromatographic	1671:1685	arg1	investigations					1687:1700	the infrared spectroscopic and ion chromatographic investigations	1636:1700	investigations	1687:1700	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	4	34	theme	gas-phase	968:976	arg1	reduction					1005:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	35	theme	isothermal	601:610	arg1	adsorption					615:624	isothermal N2 adsorption	601:624	isothermal N2 adsorption	601:624	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	4	36	theme	rapid	962:966	arg1	reduction					1005:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	37	theme	agar	344:347	arg1	MnO2					353:356	MnO2	353:356	MnO2 (AM-3D)	353:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	37	theme	agar	344:347	arg1	agar					344:347	agar	344:347	agar	344:347	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	37	theme	agar	344:347	arg1	composite					331:339	The 3D composite	324:339	The 3D composite of agar and MnO2 (AM-3D)	324:364	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	38	theme	powdered	397:404	arg1	counterparts					406:417	powdered counterparts	397:417	powdered counterparts (including pure MnO2 and mixture of agar and MnO2)	397:468	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	39	theme	agar	455:458	arg1	MnO2					435:438	pure MnO2	430:438	pure MnO2	430:438	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	39	theme	agar	455:458	arg1	mixture					444:450	mixture	444:450	mixture of agar and MnO2	444:467	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	4	40	theme	adsorbed	1182:1189	arg1	formaldehyde					1191:1202	the adsorbed formaldehyde	1178:1202	the adsorbed formaldehyde	1178:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	41	theme	formaldehyde	1335:1346	arg1	oxidation					1348:1356	formaldehyde oxidation	1335:1356	formaldehyde oxidation	1335:1356	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	3	42	theme	mg/m3	774:778	arg1	formaldehyde					780:791	~400 mg/m3 formaldehyde	769:791	~400 mg/m3 formaldehyde	769:791	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	6	43	from	spectroscopic	1649:1661	arg1	intermediates					1717:1729	the surface intermediates	1705:1729	the surface intermediates of the spent materials	1705:1752	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	0	44	theme	MnO2-agar	15:23	arg1	network					25:31	3D MnO2-agar network	12:31	3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation	12:104	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	4	45	theme	HCHO-to-CO2	1243:1253	arg1	converter					1255:1263	a much better HCHO-to-CO2 converter	1229:1263	a much better HCHO-to-CO2 converter	1229:1263	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	45	theme	HCHO-to-CO2	1243:1253	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	45	theme	HCHO-to-CO2	1243:1253	arg1	interaction					1031:1041	the strong interaction	1020:1041	the strong interaction between the dispersed MnO2 particles	1020:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	46	theme	agar	1084:1087	arg1	composite					1215:1223	the AM-3D composite	1205:1223	the AM-3D composite	1205:1223	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	46	theme	agar	1084:1087	arg1	converter					1255:1263	a much better HCHO-to-CO2 converter	1229:1263	a much better HCHO-to-CO2 converter	1229:1263	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	46	theme	agar	1084:1087	arg1	interaction					1031:1041	the strong interaction	1020:1041	the strong interaction between the dispersed MnO2 particles	1020:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	46	theme	agar	1084:1087	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	0	47	theme	high	38:41	arg1	performance					57:67	high and longevous performance	38:67	high and longevous performance	38:67	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	3	48	theme	AM-3D	709:713	arg1	catalyst					715:722	the AM-3D catalyst	705:722	the AM-3D catalyst	705:722	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	4	49	theme	porous	891:896	arg1	scaffold					906:913	the porous 3D agar scaffold	887:913	the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	887:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	50	theme	better	1236:1241	arg1	converter					1255:1263	a much better HCHO-to-CO2 converter	1229:1263	a much better HCHO-to-CO2 converter	1229:1263	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	50	theme	better	1236:1241	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	50	theme	better	1236:1241	arg1	interaction					1031:1041	the strong interaction	1020:1041	the strong interaction between the dispersed MnO2 particles	1020:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	51	contain	possessed	1269:1277	arg1	substrate					1089:1097	agar substrate	1084:1097	agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1084:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	51	contain	possessed	1269:1277	arg1	converter					1255:1263	a much better HCHO-to-CO2 converter	1229:1263	a much better HCHO-to-CO2 converter	1229:1263	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	51	contain	possessed	1269:1277	arg2	stability					1302:1310	much more advantageous stability	1279:1310	much more advantageous stability for repeated cycles of formaldehyde oxidation	1279:1356	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	51	contain	possessed	1269:1277	arg1	interaction					1031:1041	the strong interaction	1020:1041	the strong interaction between the dispersed MnO2 particles	1020:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	1	52	theme	ice-templating	227:240	arg1	approach					242:249	ice-templating approach	227:249	ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder	227:321	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	3	53	theme	-67.0	739:743	arg1	%					744:744	%	744:744	%	744:744	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	5	54	theme	used	1515:1518	arg1	catalyst					1526:1533	the used AM-3D catalyst	1511:1533	the used AM-3D catalyst	1511:1533	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35341871	3	55	theme	removal	746:752	arg1	percentage					754:763	-67.0% removal percentage	739:763	62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples	734:865	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	0	56	with	network	25:31	arg1	performance					57:67	high and longevous performance	38:67	high and longevous performance	38:67	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	2	57	theme	pure	430:433	arg1	MnO2					435:438	pure MnO2	430:438	pure MnO2	430:438	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	0	58	theme	longevous	47:55	arg1	performance					57:67	high and longevous performance	38:67	high and longevous performance	38:67	Ultra-light 3D MnO2-agar network with high and longevous performance for catalytic formaldehyde oxidation.					
35341871	3	59	theme	%	744:744	arg1	percentage					754:763	-67.0% removal percentage	739:763	62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples	734:865	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	6	60	theme	infrared	1640:1647	arg1	spectroscopic					1649:1661	the infrared spectroscopic and ion chromatographic investigations	1636:1700	spectroscopic	1649:1661	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	4	61	theme	large	920:924	arg1	volume					934:939	large spatial volume	920:939	large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	920:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	5	62	theme	fresh	1577:1581	arg1	one					1583:1585	the fresh one	1573:1585	the fresh one	1573:1585	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35341871	4	63	theme	formaldehyde	1407:1418	arg1	%					1402:1402	41.7%	1398:1402	41.7% of formaldehyde removed	1398:1426	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	63	theme	formaldehyde	1407:1418	arg1	formaldehyde					1407:1418	formaldehyde	1407:1418	formaldehyde removed	1407:1426	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	1	64	theme	decontamination	155:169	arg1	background					117:126	the background	113:126	the background of indoor air formaldehyde decontamination	113:169	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	6	65	theme	spent	1738:1742	arg1	materials					1744:1752	the spent materials	1734:1752	the spent materials	1734:1752	Finally, reaction pathways were put forward via the infrared spectroscopic and ion chromatographic investigations on the surface intermediates of the spent materials.					
35341871	4	66	theme	oxidation	1348:1356	arg1	cycles					1325:1330	repeated cycles	1316:1330	repeated cycles of formaldehyde oxidation	1316:1356	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	67	dep	counterparts	406:417	arg1	including					420:428	including	420:428	including pure MnO2 and mixture of agar and MnO2	420:467	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	4	68	theme	species	1151:1157	arg1	amount					1125:1130	a large amount	1117:1130	a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1117:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	68	theme	species	1151:1157	arg1	species					1151:1157	reactive oxygen species	1135:1157	reactive oxygen species	1135:1157	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	1	69	theme	indoor	131:136	arg1	decontamination					155:169	indoor air formaldehyde decontamination	131:169	indoor air formaldehyde decontamination	131:169	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	3	70	theme	significant	820:830	arg1	advantage					832:840	significant advantage	820:840	significant advantage over the control samples	820:865	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	4	71	theme	oxygen	1144:1149	arg1	species					1151:1157	reactive oxygen species	1135:1157	reactive oxygen species	1135:1157	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	72	theme	large	1119:1123	arg1	amount					1125:1130	a large amount	1117:1130	a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde	1117:1202	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	72	theme	large	1119:1123	arg1	species					1151:1157	reactive oxygen species	1135:1157	reactive oxygen species	1135:1157	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	1	73	theme	air	138:140	arg1	decontamination					155:169	indoor air formaldehyde decontamination	131:169	indoor air formaldehyde decontamination	131:169	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	4	74	theme	dispersed	1055:1063	arg1	particles					1070:1078	the dispersed MnO2 particles	1051:1078	the dispersed MnO2 particles	1051:1078	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	3	75	theme	~400	769:772	arg1	mg/m3					774:778	mg/m3	774:778	mg/m3	774:778	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	4	76	theme	spatial	926:932	arg1	volume					934:939	large spatial volume	920:939	large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	920:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	4	77	with	scaffold	906:913	arg1	volume					934:939	large spatial volume	920:939	large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction	920:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	1	78	theme	formaldehyde	142:153	arg1	decontamination					155:169	indoor air formaldehyde decontamination	131:169	indoor air formaldehyde decontamination	131:169	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	1	79	theme	MnO2	265:268	arg1	nanoparticles					270:282	MnO2 nanoparticles	265:282	MnO2 nanoparticles	265:282	Under the background of indoor air formaldehyde decontamination, a freestanding ultra-light assembly was fabricated via ice-templating approach starting from MnO2 nanoparticles and environmentally benign agar powder.					
35341871	2	80	theme	formaldehyde	501:512	arg1	oxidation					514:522	formaldehyde oxidation	501:522	formaldehyde oxidation	501:522	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	3	81	theme	single	666:671	arg1	test					673:676	the single test	662:676	the single test of formaldehyde oxidation	662:702	For the single test of formaldehyde oxidation, the AM-3D catalyst exhibited 62.0%-67.0% removal percentage for ~400 mg/m3 formaldehyde, which did not demonstrate significant advantage over the control samples.					
35341871	4	82	theme	concentration	991:1003	arg1	reduction					1005:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	a rapid gas-phase formaldehyde concentration reduction	960:1013	However, thanks to the porous 3D agar scaffold with large spatial volume that could promote a rapid gas-phase formaldehyde concentration reduction, and the strong interaction between the dispersed MnO2 particles and agar substrate that could afford a large amount of reactive oxygen species to further oxidize the adsorbed formaldehyde, the AM-3D composite was a much better HCHO-to-CO2 converter and possessed much more advantageous stability for repeated cycles of formaldehyde oxidation: even after ten cycles, there was still 41.7% of formaldehyde removed.					
35341871	2	83	theme	MnO2	464:467	arg1	MnO2					435:438	pure MnO2	430:438	pure MnO2	430:438	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	2	83	theme	MnO2	464:467	arg1	mixture					444:450	mixture	444:450	mixture of agar and MnO2	444:467	The 3D composite of agar and MnO2 (AM-3D) was comparatively studied with powdered counterparts (including pure MnO2 and mixture of agar and MnO2) and the 3D-structured agar for formaldehyde oxidation, and their physicochemical properties were examined with XRD, ATR, SEM, XPS, isothermal N2 adsorption, ESR, Raman, CO-TPR and O2-TPD.					
35341871	5	84	theme	catalyst	1526:1533	arg1	activity					1499:1506	the activity	1495:1506	the activity of the used AM-3D catalyst	1495:1533	Furthermore, the viable sunlight irradiation could easily restore the activity of the used AM-3D catalyst back to the level approaching that of the fresh one.					
35180535	2	0	theme	cellulose	372:380	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	9	1	theme	QMCC	1425:1428	arg1	column					1460:1465	a preconcentration column	1441:1465	a preconcentration column	1441:1465	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	9	1	theme	QMCC	1425:1428	arg1	aerogel					1430:1436	CPC-MT@QMCC aerogel	1418:1436	CPC-MT@QMCC aerogel	1418:1436	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	8	2	from	%	1199:1199	arg1	samples					1255:1261	environmental manure wastewater samples	1223:1261	environmental manure wastewater samples	1223:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	1	3	theme	pollution	288:296	arg1	control					298:304	pollution control	288:304	pollution control	288:304	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	4	4	theme	ion-column	699:708	arg1	chromatography					710:723	ion-column chromatography	699:723	ion-column chromatography	699:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	9	5	theme	@	1424:1424	arg1	column					1460:1465	a preconcentration column	1441:1465	a preconcentration column	1441:1465	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	9	5	theme	@	1424:1424	arg1	aerogel					1430:1436	CPC-MT@QMCC aerogel	1418:1436	CPC-MT@QMCC aerogel	1418:1436	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	5	6	theme	surface	836:842	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	6	theme	surface	836:842	arg1	320 m2 g-1					850:859	320 m2 g-1	850:859	320 m2 g-1	850:859	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	6	theme	surface	836:842	arg1	area					844:847	large specific surface area	821:847	large specific surface area (320 m2 g-1)	821:860	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	1	7	theme	solid	197:201	arg1	material					226:233	a solid phase extraction (SPE) material	195:233	a solid phase extraction (SPE) material	195:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	10	8	theme	chromatographic	1617:1631	arg1	media					1633:1637	chromatographic media	1617:1637	chromatographic media	1617:1637	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	1	9	theme	extraction	209:218	arg1	material					226:233	a solid phase extraction (SPE) material	195:233	a solid phase extraction (SPE) material	195:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	8	10	theme	anion	1212:1216	arg1	%					1199:1199	96%	1197:1199	96% of nitrate anion from environmental manure wastewater samples	1197:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	8	10	theme	anion	1212:1216	arg1	anion					1212:1216	nitrate anion	1204:1216	nitrate anion from environmental manure wastewater samples	1204:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	6	11	theme	CPC-MT	977:982	arg1	aerogel					989:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	8	12	theme	%	1286:1286	arg1	recovery					1288:1295	98.7% recovery	1282:1295	98.7% recovery	1282:1295	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	10	13	theme	high	1601:1604	arg1	efficiency					1606:1615	high efficiency	1601:1615	high efficiency	1601:1615	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	4	14	from	wastewater	671:680	arg1	anions					653:658	anions	653:658	anions from dairy wastewater by coupling with ion-column chromatography	653:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	1	15	theme	SPE	221:223	arg1	material					226:233	a solid phase extraction (SPE) material	195:233	a solid phase extraction (SPE) material	195:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	8	16	theme	environmental	1223:1235	arg1	samples					1255:1261	environmental manure wastewater samples	1223:1261	environmental manure wastewater samples	1223:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	5	17	theme	CPC-MT	766:771	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	17	theme	CPC-MT	766:771	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	18	theme	porosity	863:870	arg1	%					874:874	porosity 70%	863:874	porosity 70%	863:874	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	18	theme	porosity	863:870	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	8	19	theme	wastewater	1244:1253	arg1	samples					1255:1261	environmental manure wastewater samples	1223:1261	environmental manure wastewater samples	1223:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	0	20	from	preconcentration	76:91	arg1	wastewater					124:133	dairy wastewater	118:133	dairy wastewater	118:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	4	21	used	used	624:627	arg2	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	21	used	used	624:627	arg2	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	5	22	theme	quaternized	734:744	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	22	theme	quaternized	734:744	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	0	23	from	wastewater	124:133	arg1	preconcentration					76:91	preconcentration	76:91	preconcentration of inorganic anions from dairy wastewater	76:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	0	23	from	wastewater	124:133	arg1	anions					106:111	inorganic anions	96:111	inorganic anions from dairy wastewater	96:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	5	24	theme	@	752:752	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	24	theme	@	752:752	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	1	25	theme	adsorbents	161:170	arg1	Development					136:146	Development	136:146	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material	136:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	6	26	theme	reuse	1031:1035	arg1	performances					1037:1048	efficient regeneration and reuse performances	1004:1048	efficient regeneration and reuse performances for up to 10 cycles	1004:1068	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	5	27	theme	low	793:795	arg1	capacity					907:914	800 mg g-1 nitrate adsorption capacity	877:914	800 mg g-1 nitrate adsorption capacity	877:914	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	27	theme	low	793:795	arg1	area					844:847	large specific surface area	821:847	large specific surface area (320 m2 g-1)	821:860	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	27	theme	low	793:795	arg1	10.6 mg cm-3					806:817	10.6 mg cm-3	806:817	10.6 mg cm-3	806:817	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	27	theme	low	793:795	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	27	theme	low	793:795	arg1	%					874:874	porosity 70%	863:874	porosity 70%	863:874	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	28	theme	adsorption	896:905	arg1	capacity					907:914	800 mg g-1 nitrate adsorption capacity	877:914	800 mg g-1 nitrate adsorption capacity	877:914	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	28	theme	adsorption	896:905	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	6	29	theme	regeneration	1014:1025	arg1	performances					1037:1048	efficient regeneration and reuse performances	1004:1048	efficient regeneration and reuse performances for up to 10 cycles	1004:1068	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	0	30	theme	inorganic	96:104	arg1	anions					106:111	inorganic anions	96:111	inorganic anions from dairy wastewater	96:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	9	31	theme	linear	1305:1310	arg1	relationship					1312:1323	A good linear relationship	1298:1323	A good linear relationship	1298:1323	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	6	32	theme	QMCC	984:987	arg1	aerogel					989:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	6	33	dep	10	1060:1061	arg1	to					1057:1058	to	1057:1058	to	1057:1058	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	5	34	from	ease	934:937	arg1	solutions					962:970	alkaline solutions	953:970	alkaline solutions	953:970	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	3	35	theme	imbedded	426:433	arg1	CPC-MT					452:457	CPC-MT	452:457	CPC-MT	452:457	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	3	35	theme	imbedded	426:433	arg1	montmorillonite					435:449	Cationic cetylpyridinium imbedded montmorillonite	401:449	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT)	401:458	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	10	36	theme	successful	1472:1481	arg1	synthesis					1483:1491	The successful synthesis	1468:1491	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel	1468:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	0	37	theme	Cationic	0:7	arg1	cellulose					26:34	Cationic microcrystalline cellulose	0:34	Cationic microcrystalline cellulose	0:34	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	5	38	from	60 min	923:928	arg1	solutions					962:970	alkaline solutions	953:970	alkaline solutions	953:970	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	3	39	theme	Cationic	401:408	arg1	CPC-MT					452:457	CPC-MT	452:457	CPC-MT	452:457	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	3	39	theme	Cationic	401:408	arg1	montmorillonite					435:449	Cationic cetylpyridinium imbedded montmorillonite	401:449	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT)	401:458	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	4	40	theme	@	607:607	arg1	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	40	theme	@	607:607	arg1	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	10	41	theme	economic	1516:1523	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	9	42	theme	0.01-10 mg L-1	1354:1367	arg1	range					1345:1349	the range	1341:1349	the range of 0.01-10 mg L-1	1341:1367	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	10	43	theme	intriguing	1501:1510	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	0	44	theme	Montmorillonite	38:52	arg1	composite					54:62	Montmorillonite composite	38:62	Montmorillonite composite	38:62	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	10	45	theme	aerogel	1537:1543	arg1	synthesis					1483:1491	The successful synthesis	1468:1491	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel	1468:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	3	46	theme	anionic	531:537	arg1	efficiency					550:559	anionic adsorption efficiency	531:559	anionic adsorption efficiency	531:559	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	5	47	theme	large	821:825	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	47	theme	large	821:825	arg1	320 m2 g-1					850:859	320 m2 g-1	850:859	320 m2 g-1	850:859	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	47	theme	large	821:825	arg1	area					844:847	large specific surface area	821:847	large specific surface area (320 m2 g-1)	821:860	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	7	48	theme	binding	1099:1105	arg1	efficiency					1107:1116	a dynamic binding efficiency	1089:1116	a dynamic binding efficiency of 710 mg g-1	1089:1130	More importantly, a dynamic binding efficiency of 710 mg g-1 highlights its excellent performance for practical applications.					
35180535	4	49	theme	developed	591:599	arg1	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	49	theme	developed	591:599	arg1	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	10	50	theme	@	1531:1531	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	2	51	theme	hybrid	339:344	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	1	52	theme	inorganic	175:183	arg1	anions					185:190	inorganic anions	175:190	inorganic anions as a solid phase extraction (SPE) material	175:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	4	53	theme	adsorbent	639:647	arg1	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	53	theme	adsorbent	639:647	arg1	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	10	54	theme	promising	1559:1567	arg1	matrix					1569:1574	a promising matrix	1557:1574	a promising matrix for high-performance and high efficiency chromatographic media	1557:1637	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	3	55	theme	mechanical	565:574	arg1	stability					576:584	mechanical stability	565:584	mechanical stability	565:584	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	9	56	theme	preconcentration	1443:1458	arg1	column					1460:1465	a preconcentration column	1441:1465	a preconcentration column	1441:1465	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	9	56	theme	preconcentration	1443:1458	arg1	aerogel					1430:1436	CPC-MT@QMCC aerogel	1418:1436	CPC-MT@QMCC aerogel	1418:1436	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	7	57	theme	710 mg g-1	1121:1130	arg1	efficiency					1107:1116	a dynamic binding efficiency	1089:1116	a dynamic binding efficiency of 710 mg g-1	1089:1130	More importantly, a dynamic binding efficiency of 710 mg g-1 highlights its excellent performance for practical applications.					
35180535	2	58	theme	aerogel	382:388	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	1	59	theme	chromatographic	259:273	arg1	analysis					275:282	chromatographic analysis	259:282	chromatographic analysis	259:282	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	2	60	theme	microcrystalline	355:370	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	7	61	theme	dynamic	1091:1097	arg1	efficiency					1107:1116	a dynamic binding efficiency	1089:1116	a dynamic binding efficiency of 710 mg g-1	1089:1130	More importantly, a dynamic binding efficiency of 710 mg g-1 highlights its excellent performance for practical applications.					
35180535	7	62	theme	excellent	1147:1155	arg1	performance					1157:1167	its excellent performance	1143:1167	its excellent performance for practical applications	1143:1194	More importantly, a dynamic binding efficiency of 710 mg g-1 highlights its excellent performance for practical applications.					
35180535	1	63	theme	phase	203:207	arg1	material					226:233	a solid phase extraction (SPE) material	195:233	a solid phase extraction (SPE) material	195:233	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	6	64	theme	@	983:983	arg1	aerogel					989:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel	973:995	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	5	65	theme	MCC	753:755	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	65	theme	MCC	753:755	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	8	66	theme	nitrate	1204:1210	arg1	anion					1212:1216	nitrate anion	1204:1216	nitrate anion from environmental manure wastewater samples	1204:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	4	67	theme	dairy	665:669	arg1	wastewater					671:680	dairy wastewater	665:680	dairy wastewater by coupling with ion-column chromatography	665:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	2	68	theme	cationic	346:353	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	5	69	theme	800 mg g-1	877:886	arg1	capacity					907:914	800 mg g-1 nitrate adsorption capacity	877:914	800 mg g-1 nitrate adsorption capacity	877:914	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	69	theme	800 mg g-1	877:886	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	70	theme	@	772:772	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	70	theme	@	772:772	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	71	theme	Further	726:732	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	71	theme	Further	726:732	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	8	72	theme	manure	1237:1242	arg1	samples					1255:1261	environmental manure wastewater samples	1223:1261	environmental manure wastewater samples	1223:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	5	73	theme	CPC-MT	746:751	arg1	aerogel					757:763	Further quaternized CPC-MT@MCC aerogel	726:763	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC)	726:777	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	73	theme	CPC-MT	746:751	arg1	QMCC					773:776	CPC-MT@QMCC	766:776	CPC-MT@QMCC	766:776	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	8	74	from	samples	1255:1261	arg1	%					1199:1199	96%	1197:1199	96% of nitrate anion from environmental manure wastewater samples	1197:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	8	74	from	samples	1255:1261	arg1	anion					1212:1216	nitrate anion	1204:1216	nitrate anion from environmental manure wastewater samples	1204:1261	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	1	75	theme	efficient	151:159	arg1	adsorbents					161:170	efficient adsorbents	151:170	efficient adsorbents	151:170	Development of efficient adsorbents to inorganic anions as a solid phase extraction (SPE) material is highly desirable for chromatographic analysis and pollution control.					
35180535	5	76	theme	unique	786:791	arg1	capacity					907:914	800 mg g-1 nitrate adsorption capacity	877:914	800 mg g-1 nitrate adsorption capacity	877:914	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	76	theme	unique	786:791	arg1	area					844:847	large specific surface area	821:847	large specific surface area (320 m2 g-1)	821:860	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	76	theme	unique	786:791	arg1	10.6 mg cm-3					806:817	10.6 mg cm-3	806:817	10.6 mg cm-3	806:817	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	76	theme	unique	786:791	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	76	theme	unique	786:791	arg1	%					874:874	porosity 70%	863:874	porosity 70%	863:874	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	77	theme	nitrate	888:894	arg1	capacity					907:914	800 mg g-1 nitrate adsorption capacity	877:914	800 mg g-1 nitrate adsorption capacity	877:914	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	77	theme	nitrate	888:894	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	0	78	theme	anions	106:111	arg1	preconcentration					76:91	preconcentration	76:91	preconcentration of inorganic anions from dairy wastewater	76:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	9	79	theme	good	1300:1303	arg1	relationship					1312:1323	A good linear relationship	1298:1323	A good linear relationship	1298:1323	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	6	80	theme	efficient	1004:1012	arg1	performances					1037:1048	efficient regeneration and reuse performances	1004:1048	efficient regeneration and reuse performances for up to 10 cycles	1004:1068	The CPC-MT@QMCC aerogel showed efficient regeneration and reuse performances for up to 10 cycles.					
35180535	0	81	theme	dairy	118:122	arg1	wastewater					124:133	dairy wastewater	118:133	dairy wastewater	118:133	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	8	82	theme	98.7	1282:1285	arg1	%					1286:1286	%	1286:1286	%	1286:1286	96% of nitrate anion from environmental manure wastewater samples were adsorbed with 98.7% recovery.					
35180535	3	83	theme	microcrystalline	487:502	arg1	MCC					515:517	MCC	515:517	MCC	515:517	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	3	83	theme	microcrystalline	487:502	arg1	cellulose					504:512	microcrystalline cellulose	487:512	microcrystalline cellulose (MCC)	487:518	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	5	84	theme	specific	827:834	arg1	density					797:803	unique low density	786:803	unique low density (10.6 mg cm-3)	786:818	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	84	theme	specific	827:834	arg1	320 m2 g-1					850:859	320 m2 g-1	850:859	320 m2 g-1	850:859	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	84	theme	specific	827:834	arg1	area					844:847	large specific surface area	821:847	large specific surface area (320 m2 g-1)	821:860	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	85	theme	elution	942:948	arg1	ease					934:937	ease	934:937	ease	934:937	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	5	85	theme	elution	942:948	arg1	60 min					923:928	60 min	923:928	60 min	923:928	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	4	86	theme	MCC	608:610	arg1	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	86	theme	MCC	608:610	arg1	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	7	87	theme	practical	1173:1181	arg1	applications					1183:1194	practical applications	1173:1194	practical applications	1173:1194	More importantly, a dynamic binding efficiency of 710 mg g-1 highlights its excellent performance for practical applications.					
35180535	5	88	theme	alkaline	953:960	arg1	solutions					962:970	alkaline solutions	953:970	alkaline solutions	953:970	Further quaternized CPC-MT@MCC aerogel (CPC-MT@QMCC) showed unique low density (10.6 mg cm-3), large specific surface area (320 m2 g-1), porosity 70%, 800 mg g-1 nitrate adsorption capacity within 60 min and ease of elution in alkaline solutions.					
35180535	3	89	theme	cetylpyridinium	410:424	arg1	CPC-MT					452:457	CPC-MT	452:457	CPC-MT	452:457	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	3	89	theme	cetylpyridinium	410:424	arg1	montmorillonite					435:449	Cationic cetylpyridinium imbedded montmorillonite	401:449	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT)	401:458	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	10	90	theme	such	1496:1499	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	10	91	dep	high-performance	1580:1595	arg1	media					1633:1637	chromatographic media	1617:1637	chromatographic media	1617:1637	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	4	92	theme	CPC-MT	601:606	arg1	SPE					635:637	an SPE	632:637	an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography	632:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	4	92	theme	CPC-MT	601:606	arg1	aerogel					612:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel	587:618	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	10	93	theme	QMCC	1532:1535	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	4	94	with	coupling	685:692	arg1	chromatography					710:723	ion-column chromatography	699:723	ion-column chromatography	699:723	The developed CPC-MT@MCC aerogel was used as an SPE adsorbent for anions from dairy wastewater by coupling with ion-column chromatography.					
35180535	3	95	theme	adsorption	539:548	arg1	efficiency					550:559	anionic adsorption efficiency	531:559	anionic adsorption efficiency	531:559	Cationic cetylpyridinium imbedded montmorillonite (CPC-MT) was uniformly entrapped in microcrystalline cellulose (MCC) to enhance anionic adsorption efficiency and mechanical stability.					
35180535	9	96	theme	detection	1387:1395	arg1	limits					1377:1382	the limits	1373:1382	the limits of detection	1373:1395	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	9	96	theme	detection	1387:1395	arg1	0.5 mg L-1					1401:1410	0.5 mg L-1	1401:1410	0.5 mg L-1	1401:1410	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	10	97	theme	CPC-MT	1525:1530	arg1	aerogel					1537:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	such intriguing and economic CPC-MT@QMCC aerogel	1496:1543	The successful synthesis of such intriguing and economic CPC-MT@QMCC aerogel may provide a promising matrix for high-performance and high efficiency chromatographic media.					
35180535	2	98	theme	new	335:337	arg1	composite					390:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	a new hybrid cationic microcrystalline cellulose aerogel composite	333:398	In this work we developed a new hybrid cationic microcrystalline cellulose aerogel composite.					
35180535	0	99	theme	microcrystalline	9:24	arg1	cellulose					26:34	Cationic microcrystalline cellulose	0:34	Cationic microcrystalline cellulose	0:34	Cationic microcrystalline cellulose - Montmorillonite composite aerogel for preconcentration of inorganic anions from dairy wastewater.					
35180535	9	100	theme	CPC-MT	1418:1423	arg1	column					1460:1465	a preconcentration column	1441:1465	a preconcentration column	1441:1465	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
35180535	9	100	theme	CPC-MT	1418:1423	arg1	aerogel					1430:1436	CPC-MT@QMCC aerogel	1418:1436	CPC-MT@QMCC aerogel	1418:1436	A good linear relationship was obtained in the range of 0.01-10 mg L-1 and the limits of detection was 0.5 mg L-1 using CPC-MT@QMCC aerogel as a preconcentration column.					
36635092	2	0	contain	have	346:349	arg1	they					341:344	they	341:344	they	341:344	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	2	0	contain	have	346:349	arg2	structures					366:375	highly similar structures	351:375	highly similar structures	351:375	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	7	1	used	used	1138:1141	arg2	they					1126:1129	they	1126:1129	they	1126:1129	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	3	2	theme	disaccharide	528:539	arg1	isomers					552:558	disaccharide structural isomers	528:558	disaccharide structural isomers with in situ methylation	528:583	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	4	3	theme	time	614:617	arg1	source					623:628	real time ion source	609:628	real time ion source	609:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	0	4	theme	Mass	89:92	arg1	Spectrometry					94:105	Ambient Ionization Tandem Mass Spectrometry	63:105	Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	63:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	0	5	with	Spectrometry	94:105	arg1	Methylation					120:130	In Situ Methylation	112:130	In Situ Methylation	112:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	1	6	theme	energy	182:187	arg1	supply					189:194	energy supply	182:194	energy supply	182:194	Carbohydrates play critically important roles in energy supply and biological functions in living systems.					
36635092	8	7	theme	direct	1253:1258	arg1	identification					1260:1273	the direct identification	1249:1273	the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1249:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	4	8	theme	real	609:612	arg1	source					623:628	real time ion source	609:628	real time ion source	609:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	0	9	theme	In	112:113	arg1	Methylation					120:130	In Situ Methylation	112:130	In Situ Methylation	112:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	6	10	theme	tandem	926:931	arg1	MS					933:934	tandem MS	926:934	tandem MS	926:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	3	11	with	isomers	552:558	arg1	methylation					573:583	in situ methylation	565:583	in situ methylation	565:583	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	8	12	from	products	1320:1327	arg1	identification					1260:1273	the direct identification	1249:1273	the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1249:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	12	from	products	1320:1327	arg1	isomers					1291:1297	disaccharide isomers	1278:1297	disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1278:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	4	13	theme	disaccharides	684:696	arg1	reaction					672:679	the methylation reaction	656:679	the methylation reaction of disaccharides with tetramethylammonium hydroxide	656:731	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	7	14	theme	forms	1218:1222	arg1	identification					1182:1195	identification	1182:1195	identification of specific isomeric forms	1182:1222	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	7	14	theme	forms	1218:1222	arg1	assignment					1151:1160	the assignment	1147:1160	the assignment of linkage type	1147:1176	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	7	15	theme	linkage	1165:1171	arg1	type					1173:1176	linkage type	1165:1176	linkage type	1165:1176	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	4	16	theme	ion	619:621	arg1	source					623:628	real time ion source	609:628	real time ion source	609:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	7	17	theme	isomeric	1209:1216	arg1	forms					1218:1222	specific isomeric forms	1200:1222	specific isomeric forms	1200:1222	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	3	18	dep	in	565:566	arg1	situ					568:571	situ	568:571	situ	568:571	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	8	19	theme	disaccharide	1278:1289	arg1	isomers					1291:1297	disaccharide isomers	1278:1297	disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1278:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	0	20	dep	In	112:113	arg1	Situ					115:118	Situ	115:118	Situ	115:118	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	4	21	theme	tetramethylammonium	703:721	arg1	hydroxide					723:731	tetramethylammonium hydroxide	703:731	tetramethylammonium hydroxide	703:731	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	3	22	theme	ambient	447:453	arg1	spectrometry					478:489	an ambient ionization tandem mass spectrometry	444:489	an ambient ionization tandem mass spectrometry method	444:496	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	6	23	theme	isomers	1000:1006	arg1	isomers					1000:1006	disaccharide structural isomers	976:1006	disaccharide structural isomers with different glycosidic linkages, compositions, and configurations	976:1075	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	23	theme	isomers	1000:1006	arg1	variety					965:971	a variety	963:971	a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations	963:1075	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	24	theme	glycosidic	1023:1032	arg1	linkages					1034:1041	different glycosidic linkages	1013:1041	different glycosidic linkages	1013:1041	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	4	25	from	analysis	597:604	arg1	source					623:628	real time ion source	609:628	real time ion source	609:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	2	26	theme	glycosidic	409:418	arg1	linkages					420:427	glycosidic linkages	409:427	glycosidic linkages	409:427	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	5	27	theme	same	845:848	arg1	time					850:853	the same time	841:853	the same time	841:853	The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time.					
36635092	7	28	theme	Characteristic	1078:1091	arg1	ions					1100:1103	Characteristic marker ions	1078:1103	Characteristic marker ions	1078:1103	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	6	29	theme	structural	989:998	arg1	isomers					1000:1006	disaccharide structural isomers	976:1006	disaccharide structural isomers with different glycosidic linkages, compositions, and configurations	976:1075	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	3	30	theme	in	565:566	arg1	methylation					573:583	in situ methylation	565:583	in situ methylation	565:583	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	1	31	theme	biological	200:209	arg1	functions					211:219	biological functions	200:219	biological functions	200:219	Carbohydrates play critically important roles in energy supply and biological functions in living systems.					
36635092	0	32	theme	Direct	0:5	arg1	Identification					7:20	Direct Identification	0:20	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.	0:131	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	4	33	theme	direct	590:595	arg1	analysis					597:604	The direct analysis	586:604	The direct analysis in real time ion source	586:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	6	34	theme	methylated	860:869	arg1	ions					879:882	The methylated product ions	856:882	The methylated product ions from full scan mass spectrometry (MS) and tandem MS	856:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	8	35	theme	sample	1375:1380	arg1	pretreatment					1382:1393	complex sample pretreatment	1367:1393	complex sample pretreatment	1367:1393	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	36	theme	complex	1367:1373	arg1	pretreatment					1382:1393	complex sample pretreatment	1367:1393	complex sample pretreatment	1367:1393	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	0	37	theme	Disaccharide	25:36	arg1	Isomers					49:55	Disaccharide Structural Isomers	25:55	Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	25:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	6	38	theme	disaccharide	976:987	arg1	isomers					1000:1006	disaccharide structural isomers	976:1006	disaccharide structural isomers with different glycosidic linkages, compositions, and configurations	976:1075	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	4	39	used	used	637:640	arg2	analysis					597:604	The direct analysis	586:604	The direct analysis in real time ion source	586:628	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	8	40	theme	chromatographic	1398:1412	arg1	separation					1414:1423	chromatographic separation	1398:1423	chromatographic separation	1398:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	6	41	with	isomers	1000:1006	arg1	compositions					1044:1055	compositions	1044:1055	compositions	1044:1055	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	41	with	isomers	1000:1006	arg1	configurations					1062:1075	configurations	1062:1075	configurations	1062:1075	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	41	with	isomers	1000:1006	arg1	linkages					1034:1041	different glycosidic linkages	1013:1041	different glycosidic linkages	1013:1041	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	3	42	theme	spectrometry	478:489	arg1	method					491:496	an ambient ionization tandem mass spectrometry method	444:496	an ambient ionization tandem mass spectrometry method	444:496	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	7	43	theme	marker	1093:1098	arg1	ions					1100:1103	Characteristic marker ions	1078:1103	Characteristic marker ions	1078:1103	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	2	44	theme	possible	386:393	arg1	positions					395:403	many possible positions	381:403	many possible positions	381:403	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	3	45	theme	structural	541:550	arg1	isomers					552:558	disaccharide structural isomers	528:558	disaccharide structural isomers with in situ methylation	528:583	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	7	46	theme	type	1173:1176	arg1	identification					1182:1195	identification	1182:1195	identification of specific isomeric forms	1182:1222	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	7	46	theme	type	1173:1176	arg1	assignment					1151:1160	the assignment	1147:1160	the assignment of linkage type	1147:1176	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36635092	1	47	theme	living	224:229	arg1	systems					231:237	living systems	224:237	living systems	224:237	Carbohydrates play critically important roles in energy supply and biological functions in living systems.					
36635092	0	48	theme	Isomers	49:55	arg1	Identification					7:20	Direct Identification	0:20	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.	0:131	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	5	49	theme	disaccharides	757:769	arg1	disaccharides					757:769	disaccharides	757:769	disaccharides	757:769	The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time.					
36635092	5	49	theme	disaccharides	757:769	arg1	groups					747:752	The hydroxyl groups	734:752	The hydroxyl groups of disaccharides	734:769	The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time.					
36635092	6	50	theme	mass	899:902	arg1	MS					918:919	MS	918:919	MS	918:919	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	50	theme	mass	899:902	arg1	spectrometry					904:915	mass spectrometry	899:915	full scan mass spectrometry (MS)	889:920	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	3	51	theme	tandem	466:471	arg1	spectrometry					478:489	an ambient ionization tandem mass spectrometry	444:489	an ambient ionization tandem mass spectrometry method	444:496	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	0	52	theme	Structural	38:47	arg1	Isomers					49:55	Disaccharide Structural Isomers	25:55	Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	25:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	6	53	theme	different	1013:1021	arg1	linkages					1034:1041	different glycosidic linkages	1013:1041	different glycosidic linkages	1013:1041	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	8	54	theme	real	1304:1307	arg1	wine					1344:1347	wine	1344:1347	wine	1344:1347	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	54	theme	real	1304:1307	arg1	products					1320:1327	real commercial products	1304:1327	real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1304:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	54	theme	real	1304:1307	arg1	honey					1337:1341	honey	1337:1341	honey	1337:1341	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	54	theme	real	1304:1307	arg1	milk					1354:1357	milk	1354:1357	milk	1354:1357	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	6	55	from	spectrometry	904:915	arg1	ions					879:882	The methylated product ions	856:882	The methylated product ions from full scan mass spectrometry (MS) and tandem MS	856:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	3	56	theme	mass	473:476	arg1	spectrometry					478:489	an ambient ionization tandem mass spectrometry	444:489	an ambient ionization tandem mass spectrometry method	444:496	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	0	57	theme	Ambient	63:69	arg1	Spectrometry					94:105	Ambient Ionization Tandem Mass Spectrometry	63:105	Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	63:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	8	58	used	used	1240:1243	arg2	method					1229:1234	The method	1225:1234	The method	1225:1234	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	6	59	theme	full	889:892	arg1	MS					918:919	MS	918:919	MS	918:919	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	59	theme	full	889:892	arg1	spectrometry					904:915	mass spectrometry	899:915	full scan mass spectrometry (MS)	889:920	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	8	60	from	identification	1260:1273	arg1	wine					1344:1347	wine	1344:1347	wine	1344:1347	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	60	from	identification	1260:1273	arg1	products					1320:1327	real commercial products	1304:1327	real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1304:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	60	from	identification	1260:1273	arg1	honey					1337:1341	honey	1337:1341	honey	1337:1341	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	60	from	identification	1260:1273	arg1	milk					1354:1357	milk	1354:1357	milk	1354:1357	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	2	61	theme	similar	358:364	arg1	structures					366:375	highly similar structures	351:375	highly similar structures	351:375	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	6	62	dep	spectrometry	904:915	arg1	scan					894:897	scan	894:897	scan	894:897	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	6	63	used	used	943:946	arg2	ions					879:882	The methylated product ions	856:882	The methylated product ions from full scan mass spectrometry (MS) and tandem MS	856:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	4	64	with	reaction	672:679	arg1	hydroxide					723:731	tetramethylammonium hydroxide	703:731	tetramethylammonium hydroxide	703:731	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	8	65	theme	commercial	1309:1318	arg1	wine					1344:1347	wine	1344:1347	wine	1344:1347	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	65	theme	commercial	1309:1318	arg1	products					1320:1327	real commercial products	1304:1327	real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1304:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	65	theme	commercial	1309:1318	arg1	honey					1337:1341	honey	1337:1341	honey	1337:1341	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	8	65	theme	commercial	1309:1318	arg1	milk					1354:1357	milk	1354:1357	milk	1354:1357	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	6	66	from	MS	933:934	arg1	ions					879:882	The methylated product ions	856:882	The methylated product ions from full scan mass spectrometry (MS) and tandem MS	856:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	5	67	theme	hydroxyl	738:745	arg1	disaccharides					757:769	disaccharides	757:769	disaccharides	757:769	The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time.					
36635092	5	67	theme	hydroxyl	738:745	arg1	groups					747:752	The hydroxyl groups	734:752	The hydroxyl groups of disaccharides	734:769	The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time.					
36635092	6	68	theme	product	871:877	arg1	ions					879:882	The methylated product ions	856:882	The methylated product ions from full scan mass spectrometry (MS) and tandem MS	856:934	The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations.					
36635092	2	69	theme	great	263:267	arg1	it					249:250	it	249:250	it	249:250	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	2	69	theme	great	263:267	arg1	challenge					269:277	a great challenge	261:277	a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages	261:427	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	0	70	theme	Tandem	82:87	arg1	Spectrometry					94:105	Ambient Ionization Tandem Mass Spectrometry	63:105	Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	63:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	4	71	theme	methylation	660:670	arg1	reaction					672:679	the methylation reaction	656:679	the methylation reaction of disaccharides with tetramethylammonium hydroxide	656:731	The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide.					
36635092	8	72	theme	isomers	1291:1297	arg1	identification					1260:1273	the direct identification	1249:1273	the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation	1249:1423	The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.					
36635092	1	73	theme	important	163:171	arg1	roles					173:177	critically important roles	152:177	critically important roles	152:177	Carbohydrates play critically important roles in energy supply and biological functions in living systems.					
36635092	3	74	theme	ionization	455:464	arg1	spectrometry					478:489	an ambient ionization tandem mass spectrometry	444:489	an ambient ionization tandem mass spectrometry method	444:496	In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation.					
36635092	0	75	theme	Ionization	71:80	arg1	Spectrometry					94:105	Ambient Ionization Tandem Mass Spectrometry	63:105	Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation	63:130	Direct Identification of Disaccharide Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry with In Situ Methylation.					
36635092	2	76	theme	many	381:384	arg1	positions					395:403	many possible positions	381:403	many possible positions	381:403	However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages.					
36635092	7	77	theme	specific	1200:1207	arg1	forms					1218:1222	specific isomeric forms	1200:1222	specific isomeric forms	1200:1222	Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms.					
36104904	4	0	theme	superior	904:911	arg1	properties					924:933	superior mechanical properties	904:933	superior mechanical properties	904:933	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	2	1	theme	efficient	371:379	arg1	fabrication					381:391	the efficient fabrication	367:391	the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties	367:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	1	2	theme	product	280:286	arg1	inhibition					288:297	eliminating product inhibition	268:297	eliminating product inhibition	268:297	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	6	3	theme	antibiotic	1304:1313	arg1	wastewater					1315:1324	dynamic catalytic sulfonamide antibiotic wastewater	1274:1324	dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator	1274:1363	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	3	4	theme	graphene	589:596	arg1	oxide					598:602	graphene oxide	589:602	graphene oxide (GO)	589:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	6	5	theme	*	1232:1232	arg1	throughput					1210:1219	a high throughput	1203:1219	a high throughput (2.17 L/min*m2)	1203:1235	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	5	theme	*	1232:1232	arg1	m2					1233:1234	2.17 L/min*m2	1222:1234	2.17 L/min*m2	1222:1234	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	6	theme	catalytic	1282:1290	arg1	wastewater					1315:1324	dynamic catalytic sulfonamide antibiotic wastewater	1274:1324	dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator	1274:1363	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	3	7	theme	embedded	575:582	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	6	8	theme	high	1205:1208	arg1	throughput					1210:1219	a high throughput	1203:1219	a high throughput (2.17 L/min*m2)	1203:1235	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	8	theme	high	1205:1208	arg1	m2					1233:1234	2.17 L/min*m2	1222:1234	2.17 L/min*m2	1222:1234	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	0	9	theme	antibiotics	133:143	arg1	removal					109:115	dynamically catalytic removal	87:115	dynamically catalytic removal of sulfonamides antibiotics	87:143	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	3	10	theme	composite	548:556	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	8	11	theme	efficient	1501:1509	arg1	strategy					1538:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	4	12	theme	BC	760:761	arg1	growth					750:755	the layer-by-layer growth	731:755	the layer-by-layer growth of BC on composite film and the addition of GO	731:802	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	8	13	theme	scalable	1515:1522	arg1	strategy					1538:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	4	14	theme	composite	766:774	arg1	film					776:779	composite film	766:779	composite film	766:779	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	6	15	theme	syringaldehyde	1341:1354	arg1	mediator					1356:1363	syringaldehyde mediator	1341:1363	syringaldehyde mediator	1341:1363	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	5	16	theme	molecular	1104:1112	arg1	brushes					1114:1120	abundant molecular brushes	1095:1120	abundant molecular brushes on composite membrane	1095:1142	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	1	17	theme	membrane	153:160	arg1	EMS					171:173	EMS	171:173	EMS	171:173	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	1	17	theme	membrane	153:160	arg1	systems					162:168	Enzyme membrane systems	146:168	Enzyme membrane systems (EMS)	146:174	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	5	18	from	brushes	1114:1120	arg1	membrane					1135:1142	composite membrane	1125:1142	composite membrane	1125:1142	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	3	19	theme	scalable	638:645	arg1	method					661:666	a scalable bio-synthesis method	636:666	a scalable bio-synthesis method	636:666	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	4	20	with	membrane	890:897	arg1	flexibility					939:949	flexibility	939:949	flexibility	939:949	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	20	with	membrane	890:897	arg1	properties					924:933	superior mechanical properties	904:933	superior mechanical properties	904:933	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	21	theme	porous	996:1001	arg1	channels					1013:1020	porous transport channels	996:1020	porous transport channels	996:1020	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	22	theme	GO	801:802	arg1	film					776:779	composite film	766:779	composite film	766:779	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	22	theme	GO	801:802	arg1	addition					789:796	the addition	785:796	the addition of GO	785:802	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	0	23	theme	catalytic	99:107	arg1	removal					109:115	dynamically catalytic removal	87:115	dynamically catalytic removal of sulfonamides antibiotics	87:143	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	5	24	theme	immobilized	1147:1157	arg1	carrier					1166:1172	immobilized enzyme carrier	1147:1172	immobilized enzyme carrier	1147:1172	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	2	25	theme	properties	456:465	arg1	fabrication					381:391	the efficient fabrication	367:391	the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties	367:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	2	26	theme	dynamic	427:433	arg1	properties					456:465	dynamic catalytic separation properties	427:465	dynamic catalytic separation properties	427:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	2	27	theme	membranes	413:421	arg1	fabrication					381:391	the efficient fabrication	367:391	the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties	367:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	0	28	theme	Strong	0:5	arg1	membrane					44:51	Strong and robust cellulose-based enzymatic membrane	0:51	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.	0:144	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	3	29	theme	flexible	496:503	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	0	30	theme	robust	11:16	arg1	membrane					44:51	Strong and robust cellulose-based enzymatic membrane	0:51	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.	0:144	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	1	31	theme	conversion	314:323	arg1	rates					325:329	enhancing conversion rates	304:329	enhancing conversion rates	304:329	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	8	32	theme	antibiotics	1605:1615	arg1	treatment					1628:1636	antibiotics wastewater treatment	1605:1636	antibiotics wastewater treatment	1605:1636	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	3	33	theme	radical	687:693	arg1	technology					710:719	atom transfer radical polymerization technology	673:719	atom transfer radical polymerization technology	673:719	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	4	34	theme	hydrogen	849:856	arg1	bonding					858:864	strong hydrogen bonding	842:864	strong hydrogen bonding	842:864	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	2	35	theme	separation	445:454	arg1	properties					456:465	dynamic catalytic separation properties	427:465	dynamic catalytic separation properties	427:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	0	36	theme	enzymatic	34:42	arg1	membrane					44:51	Strong and robust cellulose-based enzymatic membrane	0:51	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.	0:144	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	3	37	with	embedded	575:582	arg1	oxide					598:602	graphene oxide	589:602	graphene oxide (GO)	589:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	3	38	theme	atom	673:676	arg1	technology					710:719	atom transfer radical polymerization technology	673:719	atom transfer radical polymerization technology	673:719	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	4	39	theme	entangled	819:827	arg1	network					829:835	an entangled network	816:835	an entangled network with strong hydrogen bonding	816:864	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	3	40	theme	viscose/bacterial	515:531	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	2	41	theme	affinity	396:403	arg1	membranes					413:421	affinity carrier membranes	396:421	affinity carrier membranes	396:421	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	1	42	theme	reactions	257:265	arg1	advantages					230:239	their advantages	224:239	their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates	224:329	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	5	43	theme	efficient	1056:1064	arg1	EMS					1066:1068	a novel and highly efficient EMS	1037:1068	a novel and highly efficient EMS	1037:1068	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	1	44	theme	eliminating	268:278	arg1	inhibition					288:297	eliminating product inhibition	268:297	eliminating product inhibition	268:297	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	2	45	from	deficiencies	351:362	arg1	fabrication					381:391	the efficient fabrication	367:391	the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties	367:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	1	46	theme	inhibition	288:297	arg1	advantages					230:239	their advantages	224:239	their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates	224:329	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	4	47	theme	mechanical	913:922	arg1	properties					924:933	superior mechanical properties	904:933	superior mechanical properties	904:933	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	6	48	theme	sulfonamide	1292:1302	arg1	wastewater					1315:1324	dynamic catalytic sulfonamide antibiotic wastewater	1274:1324	dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator	1274:1363	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	49	theme	2.17 L/min	1222:1231	arg1	throughput					1210:1219	a high throughput	1203:1219	a high throughput (2.17 L/min*m2)	1203:1235	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	49	theme	2.17 L/min	1222:1231	arg1	m2					1233:1234	2.17 L/min*m2	1222:1234	2.17 L/min*m2	1222:1234	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	50	theme	dynamic	1274:1280	arg1	wastewater					1315:1324	dynamic catalytic sulfonamide antibiotic wastewater	1274:1324	dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator	1274:1363	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	1	51	theme	considerable	191:202	arg1	interest					204:211	considerable interest	191:211	considerable interest	191:211	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	4	52	theme	resulting	880:888	arg1	membrane					890:897	the resulting membrane	876:897	the resulting membrane with superior mechanical properties and flexibility	876:949	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	5	53	theme	composite	1125:1133	arg1	membrane					1135:1142	composite membrane	1125:1142	composite membrane	1125:1142	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	4	54	theme	gradient	973:980	arg1	structure					982:990	a gradient structure	971:990	a gradient structure	971:990	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	8	55	theme	manufacturing	1524:1536	arg1	strategy					1538:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy	1496:1545	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	5	56	theme	abundant	1095:1102	arg1	brushes					1114:1120	abundant molecular brushes	1095:1120	abundant molecular brushes on composite membrane	1095:1142	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	3	57	theme	bio-synthesis	647:659	arg1	method					661:666	a scalable bio-synthesis method	636:666	a scalable bio-synthesis method	636:666	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	1	58	theme	Enzyme	146:151	arg1	EMS					171:173	EMS	171:173	EMS	171:173	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	1	58	theme	Enzyme	146:151	arg1	systems					162:168	Enzyme membrane systems	146:168	Enzyme membrane systems (EMS)	146:174	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	6	59	theme	interception	1244:1255	arg1	rate					1257:1260	an interception rate	1241:1260	an interception rate (98.64%)	1241:1269	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	6	59	theme	interception	1244:1255	arg1	%					1268:1268	98.64%	1263:1268	98.64%	1263:1268	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	3	60	dep	oxide	598:602	arg1	GO					605:606	GO	605:606	GO	605:606	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	8	61	theme	great	1553:1557	arg1	significance					1559:1570	great significance	1553:1570	great significance	1553:1570	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	7	62	theme	sulphapyridine	1398:1411	arg1	Meanwhile					1366:1374	Meanwhile	1366:1374	Meanwhile	1366:1374	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	7	62	theme	sulphapyridine	1398:1411	arg1	%					1442:1442	97.20%	1437:1442	97.20%	1437:1442	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	7	62	theme	sulphapyridine	1398:1411	arg1	sulfamethazine					1417:1430	sulfamethazine	1417:1430	sulfamethazine	1417:1430	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	7	62	theme	sulphapyridine	1398:1411	arg1	rates					1389:1393	the removal rates	1377:1393	the removal rates of sulphapyridine	1377:1411	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	4	63	theme	layer-by-layer	735:748	arg1	growth					750:755	the layer-by-layer growth	731:755	the layer-by-layer growth of BC on composite film and the addition of GO	731:802	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	64	with	network	829:835	arg1	bonding					858:864	strong hydrogen bonding	842:864	strong hydrogen bonding	842:864	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	0	65	theme	sulfonamides	120:131	arg1	antibiotics					133:143	sulfonamides antibiotics	120:143	sulfonamides antibiotics	120:143	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	5	66	theme	enzyme	1159:1164	arg1	carrier					1166:1172	immobilized enzyme carrier	1147:1172	immobilized enzyme carrier	1147:1172	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	7	67	theme	removal	1381:1387	arg1	%					1442:1442	97.20%	1437:1442	97.20%	1437:1442	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	7	67	theme	removal	1381:1387	arg1	rates					1389:1393	the removal rates	1377:1393	the removal rates of sulphapyridine	1377:1411	Meanwhile, the removal rates of sulphapyridine and sulfamethazine were 97.20% and 94.78% under 0.14 MPa and 15 min, respectively.					
36104904	4	68	theme	transport	1003:1011	arg1	channels					1013:1020	porous transport channels	996:1020	porous transport channels	996:1020	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	0	69	from	membrane	44:51	arg1	removal					109:115	dynamically catalytic removal	87:115	dynamically catalytic removal of sulfonamides antibiotics	87:143	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	3	70	theme	strong	478:483	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	2	71	theme	carrier	405:411	arg1	membranes					413:421	affinity carrier membranes	396:421	affinity carrier membranes	396:421	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	0	72	theme	cellulose-based	18:32	arg1	membrane					44:51	Strong and robust cellulose-based enzymatic membrane	0:51	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.	0:144	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	1	73	theme	enhancing	304:312	arg1	rates					325:329	enhancing conversion rates	304:329	enhancing conversion rates	304:329	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	8	74	theme	wastewater	1617:1626	arg1	treatment					1628:1636	antibiotics wastewater treatment	1605:1636	antibiotics wastewater treatment	1605:1636	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	3	75	theme	transfer	678:685	arg1	technology					710:719	atom transfer radical polymerization technology	673:719	atom transfer radical polymerization technology	673:719	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	3	76	theme	spunlaced	505:513	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	1	77	theme	rates	325:329	arg1	advantages					230:239	their advantages	224:239	their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates	224:329	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	4	78	theme	strong	842:847	arg1	bonding					858:864	strong hydrogen bonding	842:864	strong hydrogen bonding	842:864	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	2	79	theme	catalytic	435:443	arg1	properties					456:465	dynamic catalytic separation properties	427:465	dynamic catalytic separation properties	427:465	However, there are deficiencies in the efficient fabrication of affinity carrier membranes and dynamic catalytic separation properties.					
36104904	0	80	theme	gradient	58:65	arg1	structure					74:82	gradient porous structure	58:82	gradient porous structure	58:82	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	0	81	theme	porous	67:72	arg1	structure					74:82	gradient porous structure	58:82	gradient porous structure	58:82	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	8	82	theme	novel	1587:1591	arg1	pathway					1593:1599	a novel pathway	1585:1599	a novel pathway for antibiotics wastewater treatment and recycling	1585:1650	This efficient and scalable manufacturing strategy is of great significance and may pave a novel pathway for antibiotics wastewater treatment and recycling.					
36104904	3	83	theme	BC	544:545	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	5	84	theme	novel	1039:1043	arg1	EMS					1066:1068	a novel and highly efficient EMS	1037:1068	a novel and highly efficient EMS	1037:1068	Subsequently, a novel and highly efficient EMS was constructed by using abundant molecular brushes on composite membrane as immobilized enzyme carrier.					
36104904	6	85	theme	resulting	1179:1187	arg1	EMS					1189:1191	The resulting EMS	1175:1191	The resulting EMS	1175:1191	The resulting EMS exhibited a high throughput (2.17 L/min*m2) and an interception rate (98.64%) in dynamic catalytic sulfonamide antibiotic wastewater activated with syringaldehyde mediator.					
36104904	3	86	theme	polymerization	695:708	arg1	technology					710:719	atom transfer radical polymerization technology	673:719	atom transfer radical polymerization technology	673:719	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	3	87	theme	cellulose	533:541	arg1	membrane					558:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane	476:565	a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO)	476:607	Herein, a strong and highly flexible spunlaced viscose/bacterial cellulose (BC) composite membrane in situ embedded with graphene oxide (GO) was developed by combining a scalable bio-synthesis method with atom transfer radical polymerization technology.					
36104904	1	88	theme	accelerating	244:255	arg1	reactions					257:265	accelerating reactions	244:265	accelerating reactions	244:265	Enzyme membrane systems (EMS) have generated considerable interest because of their advantages of accelerating reactions, eliminating product inhibition, and enhancing conversion rates.					
36104904	0	89	with	membrane	44:51	arg1	structure					74:82	gradient porous structure	58:82	gradient porous structure	58:82	Strong and robust cellulose-based enzymatic membrane with gradient porous structure in dynamically catalytic removal of sulfonamides antibiotics.					
36104904	4	90	from	growth	750:755	arg1	film					776:779	composite film	766:779	composite film	766:779	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
36104904	4	90	from	growth	750:755	arg1	addition					789:796	the addition	785:796	the addition of GO	785:802	Notably, the layer-by-layer growth of BC on composite film and the addition of GO resulted in an entangled network with strong hydrogen bonding, endowing the resulting membrane with superior mechanical properties and flexibility, while facilitating a gradient structure and porous transport channels.					
35648339	0	0	theme	Neural	78:83	arg1	Growth					85:90	Neural Growth	78:90	Neural Growth	78:90	Lytic Bacteriophage as a Biomaterial to Prevent Biofilm Formation and Promote Neural Growth.					
35648339	3	1	dep	METHODS	370:376	arg1	bound					407:411	bound	407:411	were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking	391:481	METHODS Lytic phages were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking.					
35648339	6	2	theme	Transmission	718:729	arg1	microscopy					740:749	Transmission electron microscopy	718:749	Transmission electron microscopy (TEM)	718:755	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	6	2	theme	Transmission	718:729	arg1	TEM					752:754	TEM	752:754	TEM	752:754	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	2	3	theme	tissue	355:360	arg1	repair					362:367	neural tissue repair	348:367	neural tissue repair	348:367	In this work a lytic bacteriophage was used to make an antibacterial biomaterial for neural tissue repair.					
35648339	13	4	theme	more	1615:1618	arg1	extensions					1625:1634	more cell extensions	1615:1634	more cell extensions	1615:1634	The neuroblast on the phage-linked sample demonstrated more cell extensions after day 1.					
35648339	4	5	theme	contact	517:523	arg1	angle					525:529	the contact angle	513:529	the contact angle of the sample surface	513:551	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	2	6	theme	neural	348:353	arg1	repair					362:367	neural tissue repair	348:367	neural tissue repair	348:367	In this work a lytic bacteriophage was used to make an antibacterial biomaterial for neural tissue repair.					
35648339	4	7	theme	lytic	571:575	arg1	potential					577:585	the remaining lytic potential	557:585	the remaining lytic potential of the phages	557:599	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	9	8	theme	control	1159:1165	arg1	p < 0.05					1177:1184	p < 0.05	1177:1184	p < 0.05	1177:1184	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	9	8	theme	control	1159:1165	arg1	chitosan					1167:1174	the control chitosan	1155:1174	the control chitosan (p < 0.05)	1155:1185	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	8	9	theme	chitosan	948:955	arg1	film					957:960	the chitosan film	944:960	the chitosan film	944:960	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	13	10	theme	phage-linked	1582:1593	arg1	sample					1595:1600	the phage-linked sample	1578:1600	the phage-linked sample	1578:1600	The neuroblast on the phage-linked sample demonstrated more cell extensions after day 1.					
35648339	15	11	theme	bacterial	1848:1856	arg1	growth					1858:1863	bacterial growth	1848:1863	bacterial growth	1848:1863	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	8	12	theme	growth	1023:1028	arg1	growth					1023:1028	bacterial growth	1013:1028	bacterial growth	1013:1028	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	8	12	theme	growth	1023:1028	arg1	%					1008:1008	68%	1006:1008	68% of bacterial growth	1006:1028	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	6	13	theme	phage-infected	792:805	arg1	bacteria					807:814	phage-infected bacteria	792:814	phage-infected bacteria	792:814	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	2	14	theme	lytic	278:282	arg1	bacteriophage					284:296	a lytic bacteriophage	276:296	a lytic bacteriophage	276:296	In this work a lytic bacteriophage was used to make an antibacterial biomaterial for neural tissue repair.					
35648339	11	15	theme	phage-linked	1409:1420	arg1	sample					1422:1427	the phage-linked sample	1405:1427	the phage-linked sample at 120 min	1405:1438	The TEM images demonstrated that the phage attached and lysed the bacteria on the phage-linked sample at 120 min.					
35648339	15	16	theme	cell	1800:1803	arg1	proliferation					1805:1817	neural cell proliferation	1793:1817	neural cell proliferation	1793:1817	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	12	17	link	phage-linked	1445:1456	arg1	sample					1458:1463	The phage-linked sample	1441:1463	The phage-linked sample	1441:1463	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	8	18	theme	sample	1037:1042	arg1	surface					1044:1050	the sample surface	1033:1050	the sample surface	1033:1050	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	8	19	theme	lytic	978:982	arg1	potential					984:992	their lytic potential	972:992	their lytic potential	972:992	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	13	20	link	phage-linked	1582:1593	arg1	sample					1595:1600	the phage-linked sample	1578:1600	the phage-linked sample	1578:1600	The neuroblast on the phage-linked sample demonstrated more cell extensions after day 1.					
35648339	4	21	theme	chemical	494:501	arg1	reaction					503:510	the chemical reaction	490:510	the chemical reaction	490:510	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	14	22	theme	lytic	1673:1677	arg1	phages					1679:1684	The purified lytic phages	1660:1684	The purified lytic phages	1660:1684	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	14	22	theme	lytic	1673:1677	arg1	nanomaterial					1723:1734	a highly bioactive nanomaterial	1704:1734	a highly bioactive nanomaterial	1704:1734	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	15	23	theme	neural	1793:1798	arg1	proliferation					1805:1817	neural cell proliferation	1793:1817	neural cell proliferation	1793:1817	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	3	24	theme	chitosan	433:440	arg1	film					442:445	a chitosan film	431:445	a chitosan film through glutaraldehyde crosslinking	431:481	METHODS Lytic phages were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking.					
35648339	9	25	contain	had	1101:1103	arg2	angle					1136:1140	a significantly higher contact angle	1105:1140	a significantly higher contact angle	1105:1140	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	9	25	contain	had	1101:1103	arg1	surface					1093:1099	The phage-linked surface	1076:1099	The phage-linked surface	1076:1099	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	14	26	dep	CONCLUSION	1649:1658	arg1	proven					1691:1696	proven	1691:1696	were proven to be a highly bioactive nanomaterial	1686:1734	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	10	27	theme	control	1238:1244	arg1	chitosan					1246:1253	the control chitosan	1234:1253	the control chitosan	1234:1253	After 120 min a bacterial biofilm appeared on the control chitosan, while the phage-linked sample effectively prevented biofilm formation.					
35648339	1	28	theme	tissue	191:196	arg1	growth					198:203	tissue growth	191:203	tissue growth	191:203	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	0	29	theme	Lytic	0:4	arg1	Bacteriophage					6:18	Lytic Bacteriophage	0:18	Lytic Bacteriophage as a Biomaterial	0:35	Lytic Bacteriophage as a Biomaterial to Prevent Biofilm Formation and Promote Neural Growth.					
35648339	5	30	theme	bacteria	631:638	arg1	numbers					620:626	The numbers	616:626	The numbers of bacteria on the samples	616:653	The numbers of bacteria on the samples were measured and examined under scanning electron microscopy.					
35648339	7	31	theme	cell	830:833	arg1	line					835:838	A neuroblast cell line	817:838	A neuroblast cell line	817:838	A neuroblast cell line was cultured on the samples to evaluate the sample's biocompatibility.					
35648339	12	32	theme	phage-linked	1445:1456	arg1	sample					1458:1463	The phage-linked sample	1441:1463	The phage-linked sample	1441:1463	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	4	33	theme	surface	545:551	arg1	angle					525:529	the contact angle	513:529	the contact angle of the sample surface	513:551	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	4	33	theme	surface	545:551	arg1	potential					577:585	the remaining lytic potential	557:585	the remaining lytic potential of the phages	557:599	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	5	34	theme	scanning	688:695	arg1	microscopy					706:715	scanning electron microscopy	688:715	scanning electron microscopy	688:715	The numbers of bacteria on the samples were measured and examined under scanning electron microscopy.					
35648339	10	35	theme	phage-linked	1266:1277	arg1	sample					1279:1284	the phage-linked sample	1262:1284	the phage-linked sample	1262:1284	After 120 min a bacterial biofilm appeared on the control chitosan, while the phage-linked sample effectively prevented biofilm formation.					
35648339	3	36	theme	glutaraldehyde	455:468	arg1	crosslinking					470:481	glutaraldehyde crosslinking	455:481	glutaraldehyde crosslinking	455:481	METHODS Lytic phages were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking.					
35648339	3	37	theme	Lytic	378:382	arg1	phages					384:389	Lytic phages	378:389	Lytic phages	378:389	METHODS Lytic phages were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking.					
35648339	4	38	theme	remaining	561:569	arg1	potential					577:585	the remaining lytic potential	557:585	the remaining lytic potential of the phages	557:599	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	5	39	theme	electron	697:704	arg1	microscopy					706:715	scanning electron microscopy	688:715	scanning electron microscopy	688:715	The numbers of bacteria on the samples were measured and examined under scanning electron microscopy.					
35648339	12	40	theme	neuroblast	1492:1501	arg1	p < 0.05					1520:1527	p < 0.05	1520:1527	p < 0.05	1520:1527	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	12	40	theme	neuroblast	1492:1501	arg1	attachment					1508:1517	the neuroblast cell attachment	1488:1517	the neuroblast cell attachment (p < 0.05)	1488:1528	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	6	41	used	used	761:764	arg2	TEM					752:754	TEM	752:754	TEM	752:754	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	6	41	used	used	761:764	arg2	microscopy					740:749	Transmission electron microscopy	718:749	Transmission electron microscopy (TEM)	718:755	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	9	42	theme	phage-linked	1080:1091	arg1	surface					1093:1099	The phage-linked surface	1076:1099	The phage-linked surface	1076:1099	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	15	43	theme	implant	1883:1889	arg1	failure					1891:1897	implant failure	1883:1897	implant failure	1883:1897	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	5	44	from	numbers	620:626	arg1	samples					647:653	the samples	643:653	the samples	643:653	The numbers of bacteria on the samples were measured and examined under scanning electron microscopy.					
35648339	7	45	theme	neuroblast	819:828	arg1	line					835:838	A neuroblast cell line	817:838	A neuroblast cell line	817:838	A neuroblast cell line was cultured on the samples to evaluate the sample's biocompatibility.					
35648339	3	46	theme	film	442:445	arg1	surface					420:426	the surface	416:426	the surface of a chitosan film through glutaraldehyde crosslinking	416:481	METHODS Lytic phages were chemically bound to the surface of a chitosan film through glutaraldehyde crosslinking.					
35648339	13	47	from	neuroblast	1564:1573	arg1	sample					1595:1600	the phage-linked sample	1578:1600	the phage-linked sample	1578:1600	The neuroblast on the phage-linked sample demonstrated more cell extensions after day 1.					
35648339	14	48	theme	bioactive	1713:1721	arg1	nanomaterial					1723:1734	a highly bioactive nanomaterial	1704:1734	a highly bioactive nanomaterial	1704:1734	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	14	48	theme	bioactive	1713:1721	arg1	phages					1679:1684	The purified lytic phages	1660:1684	The purified lytic phages	1660:1684	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	11	49	from	120 min	1432:1438	arg1	sample					1422:1427	the phage-linked sample	1405:1427	the phage-linked sample at 120 min	1405:1438	The TEM images demonstrated that the phage attached and lysed the bacteria on the phage-linked sample at 120 min.					
35648339	15	50	theme	phage-chitosan	1741:1754	arg1	material					1766:1773	The phage-chitosan composite material	1737:1773	The phage-chitosan composite material	1737:1773	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	1	51	theme	limited	215:221	arg1	ability					223:229	limited ability	215:229	limited ability to prevent bacterial infection	215:260	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	0	52	theme	Biofilm	48:54	arg1	Formation					56:64	Biofilm Formation	48:64	Biofilm Formation	48:64	Lytic Bacteriophage as a Biomaterial to Prevent Biofilm Formation and Promote Neural Growth.					
35648339	10	53	link	phage-linked	1266:1277	arg1	sample					1279:1284	the phage-linked sample	1262:1284	the phage-linked sample	1262:1284	After 120 min a bacterial biofilm appeared on the control chitosan, while the phage-linked sample effectively prevented biofilm formation.					
35648339	12	54	theme	cell	1503:1506	arg1	p < 0.05					1520:1527	p < 0.05	1520:1527	p < 0.05	1520:1527	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	12	54	theme	cell	1503:1506	arg1	attachment					1508:1517	the neuroblast cell attachment	1488:1517	the neuroblast cell attachment (p < 0.05)	1488:1528	The phage-linked sample significantly promoted the neuroblast cell attachment (p < 0.05) and proliferation (p < 0.01).					
35648339	11	55	link	phage-linked	1409:1420	arg1	sample					1422:1427	the phage-linked sample	1405:1427	the phage-linked sample at 120 min	1405:1438	The TEM images demonstrated that the phage attached and lysed the bacteria on the phage-linked sample at 120 min.					
35648339	1	56	theme	non-lytic	113:121	arg1	bacteriophages					135:148	non-lytic filamentous bacteriophages	113:148	non-lytic filamentous bacteriophages	113:148	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	11	57	theme	TEM	1331:1333	arg1	images					1335:1340	The TEM images	1327:1340	The TEM images	1327:1340	The TEM images demonstrated that the phage attached and lysed the bacteria on the phage-linked sample at 120 min.					
35648339	4	58	theme	sample	538:543	arg1	surface					545:551	the sample surface	534:551	the sample surface	534:551	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	13	59	theme	cell	1620:1623	arg1	extensions					1625:1634	more cell extensions	1615:1634	more cell extensions	1615:1634	The neuroblast on the phage-linked sample demonstrated more cell extensions after day 1.					
35648339	8	60	theme	bacterial	1013:1021	arg1	growth					1023:1028	bacterial growth	1013:1028	bacterial growth	1013:1028	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	1	61	dep	guide	185:189	arg1	made					160:163	made	160:163	have been made into biomaterial	150:180	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	10	62	theme	biofilm	1308:1314	arg1	formation					1316:1324	biofilm formation	1308:1324	biofilm formation	1308:1324	After 120 min a bacterial biofilm appeared on the control chitosan, while the phage-linked sample effectively prevented biofilm formation.					
35648339	1	63	theme	filamentous	123:133	arg1	bacteriophages					135:148	non-lytic filamentous bacteriophages	113:148	non-lytic filamentous bacteriophages	113:148	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	10	64	theme	bacterial	1204:1212	arg1	biofilm					1214:1220	a bacterial biofilm	1202:1220	a bacterial biofilm	1202:1220	After 120 min a bacterial biofilm appeared on the control chitosan, while the phage-linked sample effectively prevented biofilm formation.					
35648339	1	65	contain	had	211:213	arg1	they					206:209	they	206:209	they	206:209	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	1	65	contain	had	211:213	arg2	ability					223:229	limited ability	215:229	limited ability to prevent bacterial infection	215:260	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
35648339	9	66	theme	higher	1121:1126	arg1	angle					1136:1140	a significantly higher contact angle	1105:1140	a significantly higher contact angle	1105:1140	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	2	67	theme	antibacterial	318:330	arg1	biomaterial					332:342	an antibacterial biomaterial	315:342	an antibacterial biomaterial for neural tissue repair	315:367	In this work a lytic bacteriophage was used to make an antibacterial biomaterial for neural tissue repair.					
35648339	2	68	used	used	302:305	arg2	bacteriophage					284:296	a lytic bacteriophage	276:296	a lytic bacteriophage	276:296	In this work a lytic bacteriophage was used to make an antibacterial biomaterial for neural tissue repair.					
35648339	14	69	theme	purified	1664:1671	arg1	phages					1679:1684	The purified lytic phages	1660:1684	The purified lytic phages	1660:1684	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	14	69	theme	purified	1664:1671	arg1	nanomaterial					1723:1734	a highly bioactive nanomaterial	1704:1734	a highly bioactive nanomaterial	1704:1734	CONCLUSION The purified lytic phages were proven to be a highly bioactive nanomaterial.					
35648339	9	70	theme	contact	1128:1134	arg1	angle					1136:1140	a significantly higher contact angle	1105:1140	a significantly higher contact angle	1105:1140	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	4	71	theme	phages	594:599	arg1	angle					525:529	the contact angle	513:529	the contact angle of the sample surface	513:551	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	4	71	theme	phages	594:599	arg1	potential					577:585	the remaining lytic potential	557:585	the remaining lytic potential of the phages	557:599	After the chemical reaction, the contact angle of the sample surface and the remaining lytic potential of the phages were measured.					
35648339	8	72	dep	RESULTS	911:917	arg1	reduced					998:1004	reduced	998:1004	reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001)	998:1073	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	8	72	dep	RESULTS	911:917	arg1	preserved					962:970	preserved	962:970	preserved their lytic potential	962:992	RESULTS The phages conjugated to the chitosan film preserved their lytic potential and reduced 68% of bacterial growth on the sample surface at 120 min (p < 0.001).					
35648339	15	73	theme	failure	1891:1897	arg1	removal					1903:1909	removal	1903:1909	removal	1903:1909	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	15	73	theme	failure	1891:1897	arg1	cause					1874:1878	a major cause	1866:1878	a major cause of implant failure	1866:1897	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	15	73	theme	failure	1891:1897	arg1	growth					1858:1863	bacterial growth	1848:1863	bacterial growth	1848:1863	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	15	74	theme	composite	1756:1764	arg1	material					1766:1773	The phage-chitosan composite material	1737:1773	The phage-chitosan composite material	1737:1773	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	15	75	theme	major	1868:1872	arg1	cause					1874:1878	a major cause	1866:1878	a major cause of implant failure	1866:1897	The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.					
35648339	9	76	link	phage-linked	1080:1091	arg1	surface					1093:1099	The phage-linked surface	1076:1099	The phage-linked surface	1076:1099	The phage-linked surface had a significantly higher contact angle than that of the control chitosan (p < 0.05).					
35648339	6	77	theme	electron	731:738	arg1	microscopy					740:749	Transmission electron microscopy	718:749	Transmission electron microscopy (TEM)	718:755	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	6	77	theme	electron	731:738	arg1	TEM					752:754	TEM	752:754	TEM	752:754	Transmission electron microscopy (TEM) was used to observe the phages and phage-infected bacteria.					
35648339	1	78	theme	bacterial	242:250	arg1	infection					252:260	bacterial infection	242:260	bacterial infection	242:260	BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection.					
36347374	0	0	theme	comparative	79:89	arg1	evaluation					91:100	A comparative evaluation	77:100	A comparative evaluation	77:100	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	3	1	theme	oat	683:685	arg1	SDF					687:689	oat SDF	683:689	oat SDF	683:689	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	9	2	theme	SDF	1525:1527	arg1	feasibility					1510:1520	the feasibility	1506:1520	the feasibility of SDF to regulate blood sugar and blood lipid levels	1506:1574	To summary, these functional properties illustrated the feasibility of SDF to regulate blood sugar and blood lipid levels.					
36347374	1	3	theme	many	151:154	arg1	functions					180:188	many important physiological functions	151:188	many important physiological functions	151:188	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	5	4	theme	seed	1009:1012	arg1	PA					1028:1029	PA	1028:1029	PA	1028:1029	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	5	4	theme	seed	1009:1012	arg1	arabinoxylan					1014:1025	psyllium seed arabinoxylan	1000:1025	psyllium seed arabinoxylan (PA)	1000:1030	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	7	5	theme	inhibitory	1368:1377	arg1	activity					1379:1386	higher pancreatic lipase inhibitory activity	1343:1386	higher pancreatic lipase inhibitory activity	1343:1386	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	1	6	theme	important	156:164	arg1	functions					180:188	many important physiological functions	151:188	many important physiological functions	151:188	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	2	7	theme	functional	486:495	arg1	properties					497:506	their structural, physicochemical and functional properties	448:506	their structural, physicochemical and functional properties	448:506	In this study, SDF derived from konjac, apple, chicory, flaxseed, orange, psyllium seed, soybean and oat were purified, and their structural, physicochemical and functional properties were systematically evaluated.					
36347374	7	8	theme	higher	1343:1348	arg1	activity					1379:1386	higher pancreatic lipase inhibitory activity	1343:1386	higher pancreatic lipase inhibitory activity	1343:1386	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	0	9	link	plant-derived	14:26	arg1	fibers					44:49	plant-derived soluble dietary fibers	14:49	plant-derived soluble dietary fibers for fiber-enriched foods	14:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	3	10	theme	Monosaccharide	539:552	arg1	analysis					566:573	Monosaccharide composition analysis	539:573	Monosaccharide composition analysis	539:573	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	5	11	theme	emulsifying	1092:1102	arg1	activity					1104:1111	emulsifying activity	1092:1111	emulsifying activity	1092:1111	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	9	12	theme	blood	1541:1545	arg1	sugar					1547:1551	blood sugar and blood lipid levels	1541:1574	sugar	1547:1551	To summary, these functional properties illustrated the feasibility of SDF to regulate blood sugar and blood lipid levels.					
36347374	7	13	theme	pancreatic	1350:1359	arg1	lipase					1361:1366	pancreatic lipase	1350:1366	higher pancreatic lipase inhibitory activity	1343:1386	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	8	14	theme	cholesterol	1421:1431	arg1	capacity					1444:1451	fine cholesterol absorption capacity	1416:1451	fine cholesterol absorption capacity	1416:1451	Also, KGM and FS displayed fine cholesterol absorption capacity.					
36347374	2	15	theme	physicochemical	466:480	arg1	properties					497:506	their structural, physicochemical and functional properties	448:506	their structural, physicochemical and functional properties	448:506	In this study, SDF derived from konjac, apple, chicory, flaxseed, orange, psyllium seed, soybean and oat were purified, and their structural, physicochemical and functional properties were systematically evaluated.					
36347374	6	16	theme	texture	1152:1158	arg1	analysis					1168:1175	texture profile analysis	1152:1175	texture profile analysis	1152:1175	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	6	17	theme	profile	1160:1166	arg1	analysis					1168:1175	texture profile analysis	1152:1175	texture profile analysis	1152:1175	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	7	18	theme	α-amylase	1291:1299	arg1	activity					1312:1319	better α-amylase inhibitory activity	1284:1319	better α-amylase inhibitory activity	1284:1319	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	4	19	theme	oat	899:901	arg1	OG					911:912	OG	911:912	OG	911:912	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	19	theme	oat	899:901	arg1	glucan					903:908	oat glucan	899:908	oat glucan (OG)	899:913	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	1	20	contain	have	146:149	arg1	SDF					141:143	SDF	141:143	SDF	141:143	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	20	contain	have	146:149	arg1	fibers					133:138	Plant-derived soluble dietary fibers	103:138	Plant-derived soluble dietary fibers (SDF)	103:144	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	20	contain	have	146:149	arg2	functions					180:188	many important physiological functions	151:188	many important physiological functions	151:188	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	4	21	theme	water	926:930	arg1	solubility					932:941	higher water solubility	919:941	higher water solubility	919:941	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	0	22	dep	evaluation	91:100	arg1	Properties					0:9	Properties	0:9	Properties of plant-derived soluble dietary fibers for fiber-enriched foods	0:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	5	23	theme	swelling	1073:1080	arg1	capacity					1082:1089	swelling capacity	1073:1089	swelling capacity	1073:1089	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	9	24	theme	blood	1557:1561	arg1	levels					1569:1574	blood sugar and blood lipid levels	1541:1574	levels	1569:1574	To summary, these functional properties illustrated the feasibility of SDF to regulate blood sugar and blood lipid levels.					
36347374	1	25	link	Plant-derived	103:115	arg1	SDF					141:143	SDF	141:143	SDF	141:143	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	25	link	Plant-derived	103:115	arg1	fibers					133:138	Plant-derived soluble dietary fibers	103:138	Plant-derived soluble dietary fibers (SDF)	103:144	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	3	26	theme	composition	554:564	arg1	analysis					566:573	Monosaccharide composition analysis	539:573	Monosaccharide composition analysis	539:573	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	5	27	theme	water-holding	1049:1061	arg1	capacity					1063:1070	better water-holding capacity	1042:1070	better water-holding capacity	1042:1070	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	9	28	theme	lipid	1563:1567	arg1	levels					1569:1574	blood sugar and blood lipid levels	1541:1574	levels	1569:1574	To summary, these functional properties illustrated the feasibility of SDF to regulate blood sugar and blood lipid levels.					
36347374	7	29	theme	lipase	1361:1366	arg1	activity					1379:1386	higher pancreatic lipase inhibitory activity	1343:1386	higher pancreatic lipase inhibitory activity	1343:1386	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	1	30	dep	important	156:164	arg1	physiological					166:178	physiological	166:178	physiological	166:178	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	0	31	theme	soluble	28:34	arg1	fibers					44:49	plant-derived soluble dietary fibers	14:49	plant-derived soluble dietary fibers for fiber-enriched foods	14:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	7	32	theme	better	1284:1289	arg1	activity					1312:1319	better α-amylase inhibitory activity	1284:1319	better α-amylase inhibitory activity	1284:1319	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	7	33	theme	orange	1261:1266	arg1	OS					1273:1274	OS	1273:1274	OS	1273:1274	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	7	33	theme	orange	1261:1266	arg1	SDF					1268:1270	orange SDF	1261:1270	orange SDF (OS)	1261:1275	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	1	34	theme	Plant-derived	103:115	arg1	SDF					141:143	SDF	141:143	SDF	141:143	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	34	theme	Plant-derived	103:115	arg1	fibers					133:138	Plant-derived soluble dietary fibers	103:138	Plant-derived soluble dietary fibers (SDF)	103:144	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	4	35	dep	glucomannan	804:814	arg1	5.22 × 106 Da					822:834	5.22 × 106 Da	822:834	5.22 × 106 Da	822:834	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	35	dep	glucomannan	804:814	arg1	KGM					817:819	KGM	817:819	KGM	817:819	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	2	36	theme	psyllium	398:405	arg1	seed					407:410	psyllium seed	398:410	psyllium seed	398:410	In this study, SDF derived from konjac, apple, chicory, flaxseed, orange, psyllium seed, soybean and oat were purified, and their structural, physicochemical and functional properties were systematically evaluated.					
36347374	8	37	theme	absorption	1433:1442	arg1	capacity					1444:1451	fine cholesterol absorption capacity	1416:1451	fine cholesterol absorption capacity	1416:1451	Also, KGM and FS displayed fine cholesterol absorption capacity.					
36347374	4	38	theme	soybean	866:872	arg1	arabinogalactan					874:888	soybean arabinogalactan	866:888	soybean arabinogalactan (SA)	866:893	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	38	theme	soybean	866:872	arg1	SA					891:892	SA	891:892	SA	891:892	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	1	39	theme	soluble	117:123	arg1	SDF					141:143	SDF	141:143	SDF	141:143	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	39	theme	soluble	117:123	arg1	fibers					133:138	Plant-derived soluble dietary fibers	103:138	Plant-derived soluble dietary fibers (SDF)	103:144	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	0	40	theme	fibers	44:49	arg1	Properties					0:9	Properties	0:9	Properties of plant-derived soluble dietary fibers for fiber-enriched foods	0:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	1	41	theme	fiber-enriched	292:305	arg1	production					312:321	fiber-enriched food production	292:321	fiber-enriched food production	292:321	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	6	42	theme	gelation	1223:1230	arg1	ability					1232:1238	the best viscosity and gelation ability	1200:1238	the best viscosity and gelation ability	1200:1238	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	6	43	theme	Rheological	1128:1138	arg1	studies					1140:1146	Rheological studies	1128:1146	Rheological studies	1128:1146	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	1	44	theme	SDF	214:216	arg1	applications					198:209	the applications	194:209	the applications of SDF	194:216	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	0	45	theme	dietary	36:42	arg1	fibers					44:49	plant-derived soluble dietary fibers	14:49	plant-derived soluble dietary fibers for fiber-enriched foods	14:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	1	46	theme	food	307:310	arg1	production					312:321	fiber-enriched food production	292:321	fiber-enriched food production	292:321	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	4	47	theme	higher	919:924	arg1	solubility					932:941	higher water solubility	919:941	higher water solubility	919:941	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	5	48	theme	flaxseed	978:985	arg1	FS					992:993	FS	992:993	FS	992:993	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	5	48	theme	flaxseed	978:985	arg1	SDF					987:989	flaxseed SDF	978:989	flaxseed SDF (FS)	978:994	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	0	49	theme	fiber-enriched	55:68	arg1	foods					70:74	fiber-enriched foods	55:74	fiber-enriched foods	55:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	6	50	theme	viscosity	1209:1217	arg1	ability					1232:1238	the best viscosity and gelation ability	1200:1238	the best viscosity and gelation ability	1200:1238	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	4	51	theme	glucomannan	804:814	arg1	weight					787:792	The molecular weight	773:792	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da)	773:835	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	51	theme	glucomannan	804:814	arg1	highest					845:851	highest	845:851	highest	845:851	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	1	52	theme	dietary	125:131	arg1	SDF					141:143	SDF	141:143	SDF	141:143	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	1	52	theme	dietary	125:131	arg1	fibers					133:138	Plant-derived soluble dietary fibers	103:138	Plant-derived soluble dietary fibers (SDF)	103:144	Plant-derived soluble dietary fibers (SDF) have many important physiological functions and the applications of SDF vary based on their properties, which are worth further investigating for fiber-enriched food production.					
36347374	6	53	theme	best	1204:1207	arg1	ability					1232:1238	the best viscosity and gelation ability	1200:1238	the best viscosity and gelation ability	1200:1238	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	5	54	theme	apple	959:963	arg1	AP					973:974	AP	973:974	AP	973:974	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	5	54	theme	apple	959:963	arg1	pectin					965:970	apple pectin	959:970	apple pectin (AP)	959:975	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	4	55	theme	konjac	797:802	arg1	glucomannan					804:814	konjac glucomannan	797:814	konjac glucomannan (KGM, 5.22 × 106 Da)	797:835	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	5	56	theme	better	1042:1047	arg1	capacity					1063:1070	better water-holding capacity	1042:1070	better water-holding capacity	1042:1070	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	9	57	theme	functional	1472:1481	arg1	properties					1483:1492	these functional properties	1466:1492	these functional properties	1466:1492	To summary, these functional properties illustrated the feasibility of SDF to regulate blood sugar and blood lipid levels.					
36347374	8	58	theme	fine	1416:1419	arg1	capacity					1444:1451	fine cholesterol absorption capacity	1416:1451	fine cholesterol absorption capacity	1416:1451	Also, KGM and FS displayed fine cholesterol absorption capacity.					
36347374	3	59	theme	heteropolysaccharides	609:629	arg1	pectin					723:728	pectin	723:728	pectin	723:728	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	3	59	theme	heteropolysaccharides	609:629	arg1	glucan					751:756	glucan	751:756	glucan	751:756	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	3	59	theme	heteropolysaccharides	609:629	arg1	arabinoxylan					709:720	arabinoxylan	709:720	arabinoxylan	709:720	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	3	59	theme	heteropolysaccharides	609:629	arg1	glucomannan					696:706	glucomannan	696:706	glucomannan	696:706	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	3	59	theme	heteropolysaccharides	609:629	arg1	arabinogalactan					731:745	arabinogalactan	731:745	arabinogalactan	731:745	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	7	60	theme	inhibitory	1301:1310	arg1	activity					1312:1319	better α-amylase inhibitory activity	1284:1319	better α-amylase inhibitory activity	1284:1319	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	3	61	theme	psyllium	649:656	arg1	seed					658:661	psyllium seed	649:661	psyllium seed	649:661	Monosaccharide composition analysis showed that these SDF belonged to heteropolysaccharides, of which konjac, psyllium seed, apple, soybean and oat SDF were glucomannan, arabinoxylan, pectin, arabinogalactan and glucan, respectively.					
36347374	2	62	theme	structural	454:463	arg1	properties					497:506	their structural, physicochemical and functional properties	448:506	their structural, physicochemical and functional properties	448:506	In this study, SDF derived from konjac, apple, chicory, flaxseed, orange, psyllium seed, soybean and oat were purified, and their structural, physicochemical and functional properties were systematically evaluated.					
36347374	4	63	theme	molecular	777:785	arg1	weight					787:792	The molecular weight	773:792	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da)	773:835	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	63	theme	molecular	777:785	arg1	highest					845:851	highest	845:851	highest	845:851	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg1	arabinogalactan					874:888	soybean arabinogalactan	866:888	soybean arabinogalactan (SA)	866:893	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg1	SA					891:892	SA	891:892	SA	891:892	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg1	OG					911:912	OG	911:912	OG	911:912	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg1	inulin					858:863	inulin	858:863	inulin	858:863	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg2	solubility					932:941	higher water solubility	919:941	higher water solubility	919:941	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	4	64	contain	had	915:917	arg1	glucan					903:908	oat glucan	899:908	oat glucan (OG)	899:913	The molecular weight of konjac glucomannan (KGM, 5.22 × 106 Da) was the highest, and inulin, soybean arabinogalactan (SA) and oat glucan (OG) had higher water solubility.					
36347374	5	65	theme	psyllium	1000:1007	arg1	PA					1028:1029	PA	1028:1029	PA	1028:1029	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	5	65	theme	psyllium	1000:1007	arg1	arabinoxylan					1014:1025	psyllium seed arabinoxylan	1000:1025	psyllium seed arabinoxylan (PA)	1000:1030	Moreover, KGM, apple pectin (AP), flaxseed SDF (FS) and psyllium seed arabinoxylan (PA) exhibited better water-holding capacity, swelling capacity, emulsifying activity and stability.					
36347374	0	66	theme	plant-derived	14:26	arg1	fibers					44:49	plant-derived soluble dietary fibers	14:49	plant-derived soluble dietary fibers for fiber-enriched foods	14:74	Properties of plant-derived soluble dietary fibers for fiber-enriched foods: A comparative evaluation.					
36347374	7	67	contain	had	1339:1341	arg1	KGM					1335:1337	KGM	1335:1337	KGM	1335:1337	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	7	67	contain	had	1339:1341	arg1	OS					1328:1329	OS	1328:1329	OS	1328:1329	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	7	67	contain	had	1339:1341	arg2	activity					1379:1386	higher pancreatic lipase inhibitory activity	1343:1386	higher pancreatic lipase inhibitory activity	1343:1386	In addition, AP and orange SDF (OS) showed better α-amylase inhibitory activity, while OS and KGM had higher pancreatic lipase inhibitory activity.					
36347374	6	68	contain	had	1196:1198	arg2	ability					1232:1238	the best viscosity and gelation ability	1200:1238	the best viscosity and gelation ability	1200:1238	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36347374	6	68	contain	had	1196:1198	arg1	KGM					1192:1194	KGM	1192:1194	KGM	1192:1194	Rheological studies and texture profile analysis suggested that KGM had the best viscosity and gelation ability.					
36921822	6	0	theme	endowed	898:904	arg1	GO/HEC/PGDE/Fe3O4					880:896	The GO/HEC/PGDE/Fe3O4	876:896	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability	876:1043	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	1	1	theme	poly	196:199	arg1	PGDE					236:239	PGDE	236:239	PGDE	236:239	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	1	theme	poly	196:199	arg1	ether					229:233	poly(ethylene glycol) diglycidyl ether	196:233	poly(ethylene glycol) diglycidyl ether (PGDE)	196:240	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	2	2	from	influences	339:348	arg1	adsorption					389:398	adsorption	389:398	adsorption	389:398	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	2	from	influences	339:348	arg1	GO/HEC/PGDE/Fe3O4					367:383	GO/HEC/PGDE/Fe3O4	367:383	GO/HEC/PGDE/Fe3O4	367:383	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	2	from	influences	339:348	arg1	adsorptions					418:428	the adsorptions	414:428	the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	414:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	3	theme	content	356:362	arg1	influences					339:348	the influences	335:348	the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	335:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	4	theme	dyes	1001:1004	arg1	separation					1018:1027	convenient separation	1007:1027	convenient separation	1007:1027	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	4	theme	dyes	1001:1004	arg1	easy-fabrication					911:926	easy-fabrication	911:926	easy-fabrication	911:926	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	4	theme	dyes	1001:1004	arg1	feature					942:948	eco-friendly feature	929:948	eco-friendly feature	929:948	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	4	theme	dyes	1001:1004	arg1	reusability					1033:1043	reusability	1033:1043	reusability	1033:1043	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	4	theme	dyes	1001:1004	arg1	capacity					972:979	efficient adsorption capacity	951:979	efficient adsorption capacity of anionic/cationic dyes	951:1004	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	5	theme	dye	502:504	arg1	acid					506:509	anionic dye acid blue 25 (AB-25)	494:525	anionic dye acid blue 25 (AB-25)	494:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	6	theme	anionic/cationic	984:999	arg1	dyes					1001:1004	anionic/cationic dyes	984:1004	anionic/cationic dyes	984:1004	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	7	theme	anionic	494:500	arg1	acid					506:509	anionic dye acid blue 25 (AB-25)	494:525	anionic dye acid blue 25 (AB-25)	494:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	8	contain	has	1045:1047	arg1	GO/HEC/PGDE/Fe3O4					880:896	The GO/HEC/PGDE/Fe3O4	876:896	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability	876:1043	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	8	contain	has	1045:1047	arg2	applications					1059:1070	potential applications	1049:1070	potential applications	1049:1070	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	9	theme	Systematic	283:292	arg1	investigations					294:307	Systematic investigations	283:307	Systematic investigations	283:307	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	1	10	theme	GO/HEC/PGDE/Fe3O4	78:94	arg1	materials					96:104	GO/HEC/PGDE/Fe3O4 materials	78:104	GO/HEC/PGDE/Fe3O4 materials	78:104	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	11	theme	magnetic	267:274	arg1	Fe3O4					276:280	magnetic Fe3O4	267:280	magnetic Fe3O4	267:280	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	4	12	theme	adsorption	735:744	arg1	behaviors					746:754	the adsorption behaviors	731:754	the adsorption behaviors of the dyes	731:766	The three kinetic, four isothermic and three thermodynamic models were investigated to reveal the adsorption behaviors of the dyes.					
36921822	6	13	theme	purification	1086:1097	arg1	industry					1099:1106	wastewater purification industry	1075:1106	wastewater purification industry	1075:1106	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	1	14	theme	ethylene	201:208	arg1	PGDE					236:239	PGDE	236:239	PGDE	236:239	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	14	theme	ethylene	201:208	arg1	ether					229:233	poly(ethylene glycol) diglycidyl ether	196:233	poly(ethylene glycol) diglycidyl ether (PGDE)	196:240	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	0	15	theme	anionic/cationic	47:62	arg1	removal					69:75	anionic/cationic dyes removal	47:75	anionic/cationic dyes removal	47:75	Recoverable cellulose composite adsorbents for anionic/cationic dyes removal.					
36921822	0	16	theme	Recoverable	0:10	arg1	composite					22:30	Recoverable cellulose composite	0:30	Recoverable cellulose composite	0:30	Recoverable cellulose composite adsorbents for anionic/cationic dyes removal.					
36921822	1	17	theme	glycol	210:215	arg1	PGDE					236:239	PGDE	236:239	PGDE	236:239	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	17	theme	glycol	210:215	arg1	ether					229:233	poly(ethylene glycol) diglycidyl ether	196:233	poly(ethylene glycol) diglycidyl ether (PGDE)	196:240	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	0	18	theme	cellulose	12:20	arg1	composite					22:30	Recoverable cellulose composite	0:30	Recoverable cellulose composite	0:30	Recoverable cellulose composite adsorbents for anionic/cationic dyes removal.					
36921822	2	19	from	content	356:362	arg1	adsorption					389:398	adsorption	389:398	adsorption	389:398	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	19	from	content	356:362	arg1	GO/HEC/PGDE/Fe3O4					367:383	GO/HEC/PGDE/Fe3O4	367:383	GO/HEC/PGDE/Fe3O4	367:383	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	5	20	theme	dyes	834:837	arg1	mechanisms					816:825	HEC/PGDE/Fe3O4 and adsorption mechanisms	786:825	HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes	786:837	The formation of HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes by GO/HEC/PGDE/Fe3O4 were suggested.					
36921822	2	21	theme	blue	458:461	arg1	violet					477:482	crystal violet	469:482	crystal violet (CV)	469:487	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	21	theme	blue	458:461	arg1	methylene					448:456	methylene blue	448:461	methylene blue (MB)	448:466	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	21	theme	blue	458:461	arg1	MB					464:465	MB	464:465	MB	464:465	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	4	22	theme	thermodynamic	682:694	arg1	models					696:701	three thermodynamic models	676:701	three thermodynamic models	676:701	The three kinetic, four isothermic and three thermodynamic models were investigated to reveal the adsorption behaviors of the dyes.					
36921822	1	23	theme	diglycidyl	218:227	arg1	PGDE					236:239	PGDE	236:239	PGDE	236:239	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	23	theme	diglycidyl	218:227	arg1	ether					229:233	poly(ethylene glycol) diglycidyl ether	196:233	poly(ethylene glycol) diglycidyl ether (PGDE)	196:240	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	6	24	theme	adsorption	961:970	arg1	capacity					972:979	efficient adsorption capacity	951:979	efficient adsorption capacity of anionic/cationic dyes	951:1004	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	25	from	GO/HEC/PGDE/Fe3O4	367:383	arg1	influences					339:348	the influences	335:348	the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	335:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	26	theme	potential	1049:1057	arg1	applications					1059:1070	potential applications	1049:1070	potential applications	1049:1070	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	27	theme	dyes	442:445	arg1	adsorptions					418:428	the adsorptions	414:428	the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	414:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	28	theme	efficient	951:959	arg1	capacity					972:979	efficient adsorption capacity	951:979	efficient adsorption capacity of anionic/cationic dyes	951:1004	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	1	29	dep	oxide	252:256	arg1	GO					259:260	GO	259:260	GO	259:260	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	30	theme	environmentally-friendly	141:164	arg1	HEC					190:192	HEC	190:192	HEC	190:192	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	30	theme	environmentally-friendly	141:164	arg1	cellulose					179:187	environmentally-friendly hydroxyethyl cellulose	141:187	environmentally-friendly hydroxyethyl cellulose (HEC)	141:193	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	2	31	theme	cationic	433:440	arg1	dyes					442:445	cationic dyes	433:445	cationic dyes (methylene blue (MB), crystal violet (CV))	433:488	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	32	theme	crystal	469:475	arg1	CV					485:486	CV	485:486	CV	485:486	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	32	theme	crystal	469:475	arg1	violet					477:482	crystal violet	469:482	crystal violet (CV)	469:487	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	32	theme	crystal	469:475	arg1	methylene					448:456	methylene blue	448:461	methylene blue (MB)	448:466	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	33	theme	blue	511:514	arg1	acid					506:509	anionic dye acid blue 25 (AB-25)	494:525	anionic dye acid blue 25 (AB-25)	494:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	3	34	theme	GO/HEC/PGDE/Fe3O4	605:621	arg1	capacity					593:600	the adsorption capacity	578:600	the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes	578:634	The increase of GO content can remarkably improve the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes.					
36921822	3	35	dep	content	547:553	arg1	GO					544:545	GO	544:545	GO	544:545	The increase of GO content can remarkably improve the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes.					
36921822	5	36	theme	adsorption	805:814	arg1	mechanisms					816:825	HEC/PGDE/Fe3O4 and adsorption mechanisms	786:825	HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes	786:837	The formation of HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes by GO/HEC/PGDE/Fe3O4 were suggested.					
36921822	2	37	theme	acid	506:509	arg1	adsorptions					418:428	the adsorptions	414:428	the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	414:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	3	38	theme	adsorption	582:591	arg1	capacity					593:600	the adsorption capacity	578:600	the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes	578:634	The increase of GO content can remarkably improve the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes.					
36921822	3	39	theme	content	547:553	arg1	increase					532:539	The increase	528:539	The increase of GO content	528:553	The increase of GO content can remarkably improve the adsorption capacity of GO/HEC/PGDE/Fe3O4 for the dyes.					
36921822	5	40	theme	mechanisms	816:825	arg1	formation					773:781	The formation	769:781	The formation of HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes by GO/HEC/PGDE/Fe3O4	769:858	The formation of HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes by GO/HEC/PGDE/Fe3O4 were suggested.					
36921822	6	41	theme	eco-friendly	929:940	arg1	feature					942:948	eco-friendly feature	929:948	eco-friendly feature	929:948	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	2	42	dep	dyes	442:445	arg1	violet					477:482	crystal violet	469:482	crystal violet (CV)	469:487	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	42	dep	dyes	442:445	arg1	methylene					448:456	methylene blue	448:461	methylene blue (MB)	448:466	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	42	dep	dyes	442:445	arg1	MB					464:465	MB	464:465	MB	464:465	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	43	from	adsorption	389:398	arg1	influences					339:348	the influences	335:348	the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25)	335:525	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	1	44	theme	hydroxyethyl	166:177	arg1	HEC					190:192	HEC	190:192	HEC	190:192	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	1	44	theme	hydroxyethyl	166:177	arg1	cellulose					179:187	environmentally-friendly hydroxyethyl cellulose	141:187	environmentally-friendly hydroxyethyl cellulose (HEC)	141:193	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	0	45	theme	dyes	64:67	arg1	removal					69:75	anionic/cationic dyes removal	47:75	anionic/cationic dyes removal	47:75	Recoverable cellulose composite adsorbents for anionic/cationic dyes removal.					
36921822	2	46	dep	content	356:362	arg1	GO					353:354	GO	353:354	GO	353:354	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	2	47	dep	GO/HEC/PGDE/Fe3O4	367:383	arg1	conditions					400:409	conditions	400:409	conditions	400:409	Systematic investigations were completed to explore the influences of GO content in GO/HEC/PGDE/Fe3O4 and adsorption conditions on the adsorptions of cationic dyes (methylene blue (MB), crystal violet (CV)) and anionic dye acid blue 25 (AB-25).					
36921822	6	48	theme	wastewater	1075:1084	arg1	industry					1099:1106	wastewater purification industry	1075:1106	wastewater purification industry	1075:1106	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	49	with	endowed	898:904	arg1	separation					1018:1027	convenient separation	1007:1027	convenient separation	1007:1027	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	49	with	endowed	898:904	arg1	easy-fabrication					911:926	easy-fabrication	911:926	easy-fabrication	911:926	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	49	with	endowed	898:904	arg1	feature					942:948	eco-friendly feature	929:948	eco-friendly feature	929:948	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	49	with	endowed	898:904	arg1	capacity					972:979	efficient adsorption capacity	951:979	efficient adsorption capacity of anionic/cationic dyes	951:1004	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	6	49	with	endowed	898:904	arg1	reusability					1033:1043	reusability	1033:1043	reusability	1033:1043	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
36921822	1	50	theme	graphene	243:250	arg1	oxide					252:256	graphene oxide	243:256	graphene oxide (GO)	243:261	GO/HEC/PGDE/Fe3O4 materials were successfully fabricated using environmentally-friendly hydroxyethyl cellulose (HEC), poly(ethylene glycol) diglycidyl ether (PGDE), graphene oxide (GO) and magnetic Fe3O4.					
36921822	4	51	theme	dyes	763:766	arg1	behaviors					746:754	the adsorption behaviors	731:754	the adsorption behaviors of the dyes	731:766	The three kinetic, four isothermic and three thermodynamic models were investigated to reveal the adsorption behaviors of the dyes.					
36921822	5	52	theme	HEC/PGDE/Fe3O4	786:799	arg1	mechanisms					816:825	HEC/PGDE/Fe3O4 and adsorption mechanisms	786:825	HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes	786:837	The formation of HEC/PGDE/Fe3O4 and adsorption mechanisms of the dyes by GO/HEC/PGDE/Fe3O4 were suggested.					
36921822	6	53	theme	convenient	1007:1016	arg1	separation					1018:1027	convenient separation	1007:1027	convenient separation	1007:1027	The GO/HEC/PGDE/Fe3O4 endowed with easy-fabrication, eco-friendly feature, efficient adsorption capacity of anionic/cationic dyes, convenient separation and reusability has potential applications in wastewater purification industry.					
37105249	0	0	theme	solid	77:81	arg1	extraction					89:98	solid phase extraction	77:98	solid phase extraction of metals from corn cereal samples	77:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	2	1	theme	alginate-g-poly	476:490	arg1	matrix					504:509	alginate-g-poly(acrylamide) matrix	476:509	alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	476:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	9	2	theme	food	1624:1627	arg1	control					1629:1635	food control	1624:1635	food control	1624:1635	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	3	3	theme	cereal	707:712	arg1	sample					714:719	a digested corn cereal sample	691:719	a digested corn cereal sample before their analytical determination	691:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	4	4	theme	favorable	967:975	arg1	conditions					990:999	favorable experimental conditions	967:999	favorable experimental conditions	967:999	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	3	5	theme	Cd2+	676:679	arg1	ions					681:684	Pb2+ and Cd2+ ions	667:684	Pb2+ and Cd2+ ions	667:684	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	1	6	from	extraction	315:324	arg1	matrices					373:380	complex matrices	365:380	complex matrices	365:380	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	9	7	theme	effective	1530:1538	arg1	SPE					1540:1542	an effective SPE	1527:1542	an effective SPE	1527:1542	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	9	7	theme	effective	1530:1538	arg1	beneficial					1609:1618	beneficial	1609:1618	beneficial	1609:1618	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	9	7	theme	effective	1530:1538	arg1	ALG-g-PAAM/MWCNT-f					1504:1521	ALG-g-PAAM/MWCNT-f	1504:1521	ALG-g-PAAM/MWCNT-f	1504:1521	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	9	8	from	SPE	1540:1542	arg1	short					1497:1501	short	1497:1501	short	1497:1501	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	5	9	theme	composite	1084:1092	arg1	performance					1065:1075	the SPE performance	1057:1075	the SPE performance of the composite	1057:1092	As demonstrated, the presence of the MWCNT-f benefited the SPE performance of the composite.					
37105249	1	10	theme	analytes	351:358	arg1	pre-concentration					330:346	pre-concentration	330:346	pre-concentration	330:346	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	1	10	theme	analytes	351:358	arg1	extraction					315:324	extraction	315:324	extraction	315:324	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	7	11	dep	10	1318:1319	arg1	to					1315:1316	to	1315:1316	to	1315:1316	Also, ALG-g-PAAM/MWCNT-f showed selectivity for Pb2+, and it is reusable up to 10 times without losing sorption performance.					
37105249	6	12	theme	experimental	1176:1187	arg1	data					1189:1192	the experimental data	1172:1192	the experimental data	1172:1192	The sorption of both cations followed the pseudo-first order kinetics, while the experimental data were well-fitted by the Freundlich isotherm.					
37105249	9	13	theme	Pb2+	1581:1584	arg1	extraction					1567:1576	extraction	1567:1576	extraction	1567:1576	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	9	13	theme	Pb2+	1581:1584	arg1	separation					1552:1561	separation	1552:1561	separation	1552:1561	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	0	14	theme	phase	83:87	arg1	extraction					89:98	solid phase extraction	77:98	solid phase extraction of metals from corn cereal samples	77:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	1	15	contain	containing	156:165	arg2	nanofillers					167:177	nanofillers	167:177	nanofillers	167:177	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	1	15	contain	containing	156:165	arg1	hydrogels					146:154	Composite hydrogels	136:154	Composite hydrogels containing nanofillers	136:177	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	0	16	theme	metals	103:108	arg1	extraction					89:98	solid phase extraction	77:98	solid phase extraction of metals from corn cereal samples	77:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	1	17	dep	extraction	315:324	arg1	the					311:313	the	311:313	the	311:313	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	4	18	theme	ALG-g-PAAM/MWCNT-f	839:856	arg1	dosages					828:834	low dosages	824:834	low dosages of ALG-g-PAAM/MWCNT-f	824:856	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	0	19	theme	acrylamide	44:53	arg1	/carbon					55:61	alginate-g-poly(acrylamide)/carbon	28:61	alginate-g-poly(acrylamide)/carbon	28:61	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	3	20	theme	digested	693:700	arg1	sample					714:719	a digested corn cereal sample	691:719	a digested corn cereal sample before their analytical determination	691:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	4	21	theme	composite	766:774	arg1	characterization					776:791	composite characterization	766:791	composite characterization	766:791	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	2	22	theme	matrix	504:509	arg1	hydrogel					464:471	a composite hydrogel	452:471	a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	452:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	1	23	from	matrices	373:380	arg1	analytes					351:358	analytes	351:358	analytes from complex matrices	351:380	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	1	23	from	matrices	373:380	arg1	pre-concentration					330:346	pre-concentration	330:346	pre-concentration	330:346	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	1	23	from	matrices	373:380	arg1	extraction					315:324	extraction	315:324	extraction	315:324	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	3	24	theme	corn	702:705	arg1	sample					714:719	a digested corn cereal sample	691:719	a digested corn cereal sample before their analytical determination	691:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	1	25	theme	complex	365:371	arg1	matrices					373:380	complex matrices	365:380	complex matrices	365:380	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	3	26	theme	ions	681:684	arg1	separation					653:662	the separation	649:662	the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination	649:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	0	27	theme	Composite	0:8	arg1	hydrogel					10:17	Composite hydrogel	0:17	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon	0:61	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	3	28	theme	analytical	734:743	arg1	determination					745:757	their analytical determination	728:757	their analytical determination	728:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	6	29	theme	order	1150:1154	arg1	kinetics					1156:1163	the pseudo-first order kinetics	1133:1163	the pseudo-first order kinetics	1133:1163	The sorption of both cations followed the pseudo-first order kinetics, while the experimental data were well-fitted by the Freundlich isotherm.					
37105249	2	30	theme	multi-walled	538:549	arg1	ALG-g-PAAM/MWCNT-f					569:586	ALG-g-PAAM/MWCNT-f	569:586	ALG-g-PAAM/MWCNT-f	569:586	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	2	30	theme	multi-walled	538:549	arg1	nanotubes					558:566	functionalized multi-walled carbon nanotubes	523:566	functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	523:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	1	31	theme	different	222:230	arg1	compounds					232:240	different compounds	222:240	different compounds	222:240	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	0	32	theme	corn	115:118	arg1	samples					127:133	corn cereal samples	115:133	corn cereal samples	115:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	6	33	theme	pseudo-first	1137:1148	arg1	kinetics					1156:1163	the pseudo-first order kinetics	1133:1163	the pseudo-first order kinetics	1133:1163	The sorption of both cations followed the pseudo-first order kinetics, while the experimental data were well-fitted by the Freundlich isotherm.					
37105249	3	34	from	sample	714:719	arg1	separation					653:662	the separation	649:662	the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination	649:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	2	35	theme	carbon	551:556	arg1	ALG-g-PAAM/MWCNT-f					569:586	ALG-g-PAAM/MWCNT-f	569:586	ALG-g-PAAM/MWCNT-f	569:586	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	2	35	theme	carbon	551:556	arg1	nanotubes					558:566	functionalized multi-walled carbon nanotubes	523:566	functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	523:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	5	36	theme	SPE	1061:1063	arg1	performance					1065:1075	the SPE performance	1057:1075	the SPE performance of the composite	1057:1092	As demonstrated, the presence of the MWCNT-f benefited the SPE performance of the composite.					
37105249	2	37	theme	composite	454:462	arg1	hydrogel					464:471	a composite hydrogel	452:471	a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	452:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	2	38	theme	hydrogel	464:471	arg1	contribution					388:399	a contribution	386:399	a contribution to this field	386:413	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	2	38	theme	hydrogel	464:471	arg1	synthesis					439:447	the synthesis	435:447	the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	435:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	9	39	dep	separation	1552:1561	arg1	the					1548:1550	the	1548:1550	the	1548:1550	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	1	40	from	solutions	255:263	arg1	sorption					210:217	the sorption	206:217	the sorption of different compounds from aqueous solutions	206:263	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	0	41	theme	alginate-g-poly	28:42	arg1	/carbon					55:61	alginate-g-poly(acrylamide)/carbon	28:61	alginate-g-poly(acrylamide)/carbon	28:61	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	0	42	theme	cereal	120:125	arg1	samples					127:133	corn cereal samples	115:133	corn cereal samples	115:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	4	43	theme	experiments	806:816	arg1	series					796:801	a series	794:801	a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f	794:856	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	2	44	theme	functionalized	523:536	arg1	ALG-g-PAAM/MWCNT-f					569:586	ALG-g-PAAM/MWCNT-f	569:586	ALG-g-PAAM/MWCNT-f	569:586	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	2	44	theme	functionalized	523:536	arg1	nanotubes					558:566	functionalized multi-walled carbon nanotubes	523:566	functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	523:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	8	45	theme	MIP	1475:1477	arg1	technique					1483:1491	the MIP OES technique	1471:1491	the MIP OES technique	1471:1491	After sorption and extraction, both metals were completely recovered, facilitating their quantification by the MIP OES technique.					
37105249	4	46	theme	sorption	903:910	arg1	capacity					912:919	a higher sorption capacity	894:919	a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g)	894:959	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	6	47	theme	Freundlich	1218:1227	arg1	isotherm					1229:1236	the Freundlich isotherm	1214:1236	the Freundlich isotherm	1214:1236	The sorption of both cations followed the pseudo-first order kinetics, while the experimental data were well-fitted by the Freundlich isotherm.					
37105249	1	48	from	pre-concentration	330:346	arg1	matrices					373:380	complex matrices	365:380	complex matrices	365:380	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	4	49	theme	higher	896:901	arg1	capacity					912:919	a higher sorption capacity	894:919	a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g)	894:959	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	3	50	theme	Pb2+	667:670	arg1	ions					681:684	Pb2+ and Cd2+ ions	667:684	Pb2+ and Cd2+ ions	667:684	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	4	51	theme	low	824:826	arg1	dosages					828:834	low dosages	824:834	low dosages of ALG-g-PAAM/MWCNT-f	824:856	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	6	52	theme	cations	1116:1122	arg1	sorption					1099:1106	The sorption	1095:1106	The sorption of both cations	1095:1122	The sorption of both cations followed the pseudo-first order kinetics, while the experimental data were well-fitted by the Freundlich isotherm.					
37105249	7	53	dep	reusable	1303:1310	arg1	times					1321:1325	up to 10 times	1312:1325	up to 10 times	1312:1325	Also, ALG-g-PAAM/MWCNT-f showed selectivity for Pb2+, and it is reusable up to 10 times without losing sorption performance.					
37105249	5	54	theme	MWCNT-f	1039:1045	arg1	presence					1023:1030	the presence	1019:1030	the presence of the MWCNT-f	1019:1045	As demonstrated, the presence of the MWCNT-f benefited the SPE performance of the composite.					
37105249	7	55	theme	sorption	1342:1349	arg1	performance					1351:1361	sorption performance	1342:1361	sorption performance	1342:1361	Also, ALG-g-PAAM/MWCNT-f showed selectivity for Pb2+, and it is reusable up to 10 times without losing sorption performance.					
37105249	9	56	theme	Cd2+	1590:1593	arg1	extraction					1567:1576	extraction	1567:1576	extraction	1567:1576	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	9	56	theme	Cd2+	1590:1593	arg1	separation					1552:1561	separation	1552:1561	separation	1552:1561	In short, ALG-g-PAAM/MWCNT-f was an effective SPE for the separation and extraction of Pb2+ and Cd2+, which can be beneficial for food control and safety.					
37105249	0	57	from	samples	127:133	arg1	extraction					89:98	solid phase extraction	77:98	solid phase extraction of metals from corn cereal samples	77:133	Composite hydrogel based on alginate-g-poly(acrylamide)/carbon nanotubes for solid phase extraction of metals from corn cereal samples.					
37105249	1	58	theme	compounds	232:240	arg1	sorption					210:217	the sorption	206:217	the sorption of different compounds from aqueous solutions	206:263	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	2	59	theme	acrylamide	492:501	arg1	matrix					504:509	alginate-g-poly(acrylamide) matrix	476:509	alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f)	476:587	As a contribution to this field, this study reports the synthesis of a composite hydrogel of alginate-g-poly(acrylamide) matrix filled with functionalized multi-walled carbon nanotubes (ALG-g-PAAM/MWCNT-f).					
37105249	8	60	theme	OES	1479:1481	arg1	technique					1483:1491	the MIP OES technique	1471:1491	the MIP OES technique	1471:1491	After sorption and extraction, both metals were completely recovered, facilitating their quantification by the MIP OES technique.					
37105249	4	61	theme	experimental	977:988	arg1	conditions					990:999	favorable experimental conditions	967:999	favorable experimental conditions	967:999	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	3	62	theme	solid-phase	617:627	arg1	SPE					640:642	SPE	640:642	SPE	640:642	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	3	62	theme	solid-phase	617:627	arg1	extractor					629:637	a solid-phase extractor	615:637	a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination	615:757	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	3	62	theme	solid-phase	617:627	arg1	composite					595:603	This composite	590:603	This composite	590:603	This composite served as a solid-phase extractor (SPE) for the separation of Pb2+ and Cd2+ ions from a digested corn cereal sample before their analytical determination.					
37105249	1	63	theme	Composite	136:144	arg1	hydrogels					146:154	Composite hydrogels	136:154	Composite hydrogels containing nanofillers	136:177	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
37105249	4	64	contain	has	890:892	arg1	composite					880:888	the composite	876:888	the composite	876:888	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	4	64	contain	has	890:892	arg2	capacity					912:919	a higher sorption capacity	894:919	a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g)	894:959	After composite characterization, a series of experiments using low dosages of ALG-g-PAAM/MWCNT-f demonstrated that the composite has a higher sorption capacity for Pb2+ (5.1 mg/g) and Cd2+ (3.9 mg/g) under favorable experimental conditions.					
37105249	1	65	theme	aqueous	247:253	arg1	solutions					255:263	aqueous solutions	247:263	aqueous solutions	247:263	Composite hydrogels containing nanofillers are extensively applied in the sorption of different compounds from aqueous solutions; however, this ability is poorly exploited in the extraction and pre-concentration of analytes from complex matrices.					
35565868	4	0	theme	Genes	829:833	arg1	KEGG					848:851	KEGG	848:851	KEGG	848:851	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	4	0	theme	Genes	829:833	arg1	Genomes					839:845	Genomes	839:845	Genomes (KEGG)	839:852	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	1	1	theme	factors	293:299	arg1	interplay					229:237	the complex interplay	217:237	the complex interplay of physiological, dietary, medical, and environmental factors	217:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	4	2	theme	brain	740:744	arg1	GBMs					755:758	GBMs	755:758	GBMs	755:758	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	4	2	theme	brain	740:744	arg1	modules					746:752	gut and brain modules	732:752	modules	746:752	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	0	3	theme	Glycomacropeptide	48:64	arg1	Supplementation					72:86	Glycomacropeptide (GMP) Supplementation	48:86	Glycomacropeptide (GMP) Supplementation	48:86	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	7	4	theme	preparatory	1298:1308	arg1	phase					1310:1314	preparatory phase	1298:1314	preparatory phase of glycolysis	1298:1328	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	4	theme	preparatory	1298:1308	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	2	5	theme	microbiota	516:525	arg1	composition					471:481	composition	471:481	composition	471:481	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	2	5	theme	microbiota	516:525	arg1	function					487:494	function	487:494	function	487:494	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	8	6	theme	intestinal	1502:1511	arg1	microecology					1513:1524	the intestinal microecology	1498:1524	the intestinal microecology of VPT infants	1498:1539	The results of this study suggested that formula enriched with scGOS/lcFOS (9:1) and GPM is beneficial to the intestinal microecology of VPT infants.					
35565868	5	7	dep	coli	898:901	arg1	faecium					877:883	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae	864:950	faecium	877:883	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	0	8	from	Effects	0:6	arg1	Microbiota					99:108	the Gut Microbiota	91:108	the Gut Microbiota of Very Preterm Infants	91:132	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	2	9	theme	gut	512:514	arg1	microbiota					516:525	VPT infants' gut microbiota	499:525	VPT infants' gut microbiota	499:525	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	2	10	contain	containing	373:382	arg1	formula					365:371	an infant formula	355:371	an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	355:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	2	10	contain	containing	373:382	arg2	mixture					407:413	the specific prebiotic mixture	384:413	the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	384:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	1	11	theme	complex	221:227	arg1	interplay					229:237	the complex interplay	217:237	the complex interplay of physiological, dietary, medical, and environmental factors	217:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	0	12	theme	GMP	67:69	arg1	Supplementation					72:86	Glycomacropeptide (GMP) Supplementation	48:86	Glycomacropeptide (GMP) Supplementation	48:86	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	7	13	theme	dissimilatory	1261:1273	arg1	reduction					1283:1291	dissimilatory nitrate reduction	1261:1291	dissimilatory nitrate reduction	1261:1291	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	13	theme	dissimilatory	1261:1273	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	6	14	theme	test	1091:1094	arg1	group					1096:1100	the test group	1087:1100	the test group	1087:1100	After the 4-week intervention, the abundance of Bifidobacterium in the test group was significantly increased.					
35565868	1	15	theme	Microbial	135:143	arg1	colonization					145:156	Microbial colonization	135:156	Microbial colonization of very preterm (VPT) infants	135:186	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	2	16	theme	glycomacropeptide	440:456	arg1	mixture					407:413	the specific prebiotic mixture	384:413	the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	384:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	7	17	theme	nitrate	1275:1281	arg1	reduction					1283:1291	dissimilatory nitrate reduction	1261:1291	dissimilatory nitrate reduction	1261:1291	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	17	theme	nitrate	1275:1281	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	5	18	theme	dominant	957:964	arg1	species					966:972	dominant species	957:972	dominant species in both the test group and the control group	957:1017	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	8	19	theme	infants	1533:1539	arg1	microecology					1513:1524	the intestinal microecology	1498:1524	the intestinal microecology of VPT infants	1498:1539	The results of this study suggested that formula enriched with scGOS/lcFOS (9:1) and GPM is beneficial to the intestinal microecology of VPT infants.					
35565868	7	20	theme	acid	1161:1164	arg1	synthesis					1166:1174	quinolinic acid synthesis	1150:1174	quinolinic acid synthesis	1150:1174	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	20	theme	acid	1161:1164	arg1	GBMs					1144:1147	two GBMs	1140:1147	two GBMs (quinolinic acid synthesis and kynurenine degradation)	1140:1202	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	2	21	theme	specific	388:395	arg1	mixture					407:413	the specific prebiotic mixture	384:413	the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	384:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	3	22	dep	points	621:626	arg1	h					632:632	24 h	629:632	24 h before the trial	629:649	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	3	22	dep	points	621:626	arg1	days					669:672	7, 14, and 28 days	655:672	7, 14, and 28 days after the trial	655:688	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	4	23	theme	gut	732:734	arg1	GBMs					755:758	GBMs	755:758	GBMs	755:758	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	4	23	theme	gut	732:734	arg1	modules					746:752	gut and brain modules	732:752	modules	746:752	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	8	24	theme	VPT	1529:1531	arg1	infants					1533:1539	VPT infants	1529:1539	VPT infants	1529:1539	The results of this study suggested that formula enriched with scGOS/lcFOS (9:1) and GPM is beneficial to the intestinal microecology of VPT infants.					
35565868	6	25	theme	Bifidobacterium	1068:1082	arg1	abundance					1055:1063	the abundance	1051:1063	the abundance of Bifidobacterium in the test group	1051:1100	After the 4-week intervention, the abundance of Bifidobacterium in the test group was significantly increased.					
35565868	7	26	theme	glycolysis	1319:1328	arg1	degradation					1229:1239	glutamine degradation	1219:1239	glutamine degradation	1219:1239	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	26	theme	glycolysis	1319:1328	arg1	phase					1310:1314	preparatory phase	1298:1314	preparatory phase of glycolysis	1298:1328	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	26	theme	glycolysis	1319:1328	arg1	reduction					1283:1291	dissimilatory nitrate reduction	1261:1291	dissimilatory nitrate reduction	1261:1291	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	26	theme	glycolysis	1319:1328	arg1	glyoxylate					1242:1251	glyoxylate bypass	1242:1258	glyoxylate bypass	1242:1258	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	26	theme	glycolysis	1319:1328	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	5	27	from	species	966:972	arg1	group					991:995	the test group	982:995	the test group	982:995	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	5	27	from	species	966:972	arg1	group					1013:1017	the control group	1001:1017	the control group	1001:1017	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	7	28	dep	GMMs	1213:1216	arg1	degradation					1229:1239	glutamine degradation	1219:1239	glutamine degradation	1219:1239	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	28	dep	GMMs	1213:1216	arg1	phase					1310:1314	preparatory phase	1298:1314	preparatory phase of glycolysis	1298:1328	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	28	dep	GMMs	1213:1216	arg1	reduction					1283:1291	dissimilatory nitrate reduction	1261:1291	dissimilatory nitrate reduction	1261:1291	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	28	dep	GMMs	1213:1216	arg1	glyoxylate					1242:1251	glyoxylate bypass	1242:1258	glyoxylate bypass	1242:1258	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	28	dep	GMMs	1213:1216	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	0	29	theme	Formula	13:19	arg1	Effects					0:6	Effects	0:6	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.	0:133	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	1	30	theme	physiological	242:254	arg1	factors					293:299	physiological, dietary, medical, and environmental factors	242:299	physiological, dietary, medical, and environmental factors	242:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	0	31	theme	Gut	95:97	arg1	Microbiota					99:108	the Gut Microbiota	91:108	the Gut Microbiota of Very Preterm Infants	91:132	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	1	32	theme	preterm	166:172	arg1	infants					180:186	very preterm (VPT) infants	161:186	very preterm (VPT) infants	161:186	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	1	32	theme	preterm	166:172	arg1	VPT					175:177	VPT	175:177	VPT	175:177	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	2	33	theme	formula	365:371	arg1	effects					344:350	the effects	340:350	the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota	340:525	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	4	34	theme	metabolic	769:777	arg1	modules					779:785	gut metabolic modules	765:785	gut metabolic modules (GMMs)	765:792	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	4	34	theme	metabolic	769:777	arg1	GMMs					788:791	GMMs	788:791	GMMs	788:791	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	3	35	theme	gut	570:572	arg1	microbiota					574:583	the gut microbiota	566:583	the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial	566:688	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	7	36	theme	glutamine	1219:1227	arg1	degradation					1229:1239	glutamine degradation	1219:1239	glutamine degradation	1219:1239	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	36	theme	glutamine	1219:1227	arg1	GMMs					1213:1216	four GMMs	1208:1216	four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis)	1208:1329	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	2	37	theme	scGOS/lcFOS	418:428	arg1	mixture					407:413	the specific prebiotic mixture	384:413	the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	384:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	1	38	theme	dietary	257:263	arg1	factors					293:299	physiological, dietary, medical, and environmental factors	242:299	physiological, dietary, medical, and environmental factors	242:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	7	39	theme	test	1366:1369	arg1	group					1371:1375	the test group	1362:1375	the test group	1362:1375	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	5	40	theme	Klebsiella	904:913	arg1	aerogenes					915:923	Klebsiella aerogenes	904:923	Klebsiella aerogenes	904:923	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	7	41	dep	GBMs	1144:1147	arg1	synthesis					1166:1174	quinolinic acid synthesis	1150:1174	quinolinic acid synthesis	1150:1174	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	41	dep	GBMs	1144:1147	arg1	degradation					1191:1201	kynurenine degradation	1180:1201	kynurenine degradation	1180:1201	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	41	dep	GBMs	1144:1147	arg1	GBMs					1144:1147	two GBMs	1140:1147	two GBMs (quinolinic acid synthesis and kynurenine degradation)	1140:1202	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	2	42	from	effects	344:350	arg1	composition					471:481	composition	471:481	composition	471:481	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	2	42	from	effects	344:350	arg1	function					487:494	function	487:494	function	487:494	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	7	43	theme	quinolinic	1150:1159	arg1	synthesis					1166:1174	quinolinic acid synthesis	1150:1174	quinolinic acid synthesis	1150:1174	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	43	theme	quinolinic	1150:1159	arg1	GBMs					1144:1147	two GBMs	1140:1147	two GBMs (quinolinic acid synthesis and kynurenine degradation)	1140:1202	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	0	44	with	Formula	13:19	arg1	scGOS/lcFOS					26:36	scGOS/lcFOS	26:36	scGOS/lcFOS (9:1)	26:42	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	0	44	with	Formula	13:19	arg1	Supplementation					72:86	Glycomacropeptide (GMP) Supplementation	48:86	Glycomacropeptide (GMP) Supplementation	48:86	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	0	44	with	Formula	13:19	arg1	9:1					39:41	9:1	39:41	9:1	39:41	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	2	45	dep	composition	471:481	arg1	the					467:469	the	467:469	the	467:469	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	1	46	theme	medical	266:272	arg1	factors					293:299	physiological, dietary, medical, and environmental factors	242:299	physiological, dietary, medical, and environmental factors	242:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	0	47	theme	Preterm	118:124	arg1	Infants					126:132	Very Preterm Infants	113:132	Very Preterm Infants	113:132	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	5	48	theme	control	1005:1011	arg1	group					1013:1017	the control group	1001:1017	the control group	1001:1017	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	4	49	dep	Encyclopedia	813:824	arg1	pathways					854:861	pathways	854:861	pathways	854:861	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	7	50	dep	glyoxylate	1242:1251	arg1	bypass					1253:1258	bypass	1253:1258	bypass	1253:1258	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	2	51	theme	prebiotic	397:405	arg1	mixture					407:413	the specific prebiotic mixture	384:413	the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	384:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	8	52	theme	study	1412:1416	arg1	results					1396:1402	The results	1392:1402	The results of this study	1392:1416	The results of this study suggested that formula enriched with scGOS/lcFOS (9:1) and GPM is beneficial to the intestinal microecology of VPT infants.					
35565868	2	53	theme	VPT	499:501	arg1	infants					503:509	VPT infants'	499:510	VPT infants' gut microbiota	499:525	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	3	54	theme	infants	592:598	arg1	microbiota					574:583	the gut microbiota	566:583	the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial	566:688	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	4	55	theme	Functional	691:700	arg1	profiling					702:710	Functional profiling	691:710	Functional profiling	691:710	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	3	56	theme	time	616:619	arg1	points					621:626	four time points	611:626	four time points: 24 h before the trial and 7, 14, and 28 days after the trial	611:688	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	5	57	dep	Klebsiella	930:939	arg1	pneumoniae					941:950	Klebsiella pneumoniae	930:950	Klebsiella pneumoniae	930:950	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
35565868	4	58	theme	gut	765:767	arg1	modules					779:785	gut metabolic modules	765:785	gut metabolic modules (GMMs)	765:792	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	4	58	theme	gut	765:767	arg1	GMMs					788:791	GMMs	788:791	GMMs	788:791	Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.					
35565868	7	59	theme	kynurenine	1180:1189	arg1	degradation					1191:1201	kynurenine degradation	1180:1201	kynurenine degradation	1180:1201	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	7	59	theme	kynurenine	1180:1189	arg1	GBMs					1144:1147	two GBMs	1140:1147	two GBMs (quinolinic acid synthesis and kynurenine degradation)	1140:1202	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	1	60	theme	infants	180:186	arg1	colonization					145:156	Microbial colonization	135:156	Microbial colonization of very preterm (VPT) infants	135:186	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	0	61	theme	Infants	126:132	arg1	Microbiota					99:108	the Gut Microbiota	91:108	the Gut Microbiota of Very Preterm Infants	91:132	Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.					
35565868	6	62	theme	4-week	1030:1035	arg1	intervention					1037:1048	the 4-week intervention	1026:1048	the 4-week intervention	1026:1048	After the 4-week intervention, the abundance of Bifidobacterium in the test group was significantly increased.					
35565868	3	63	theme	VPT	588:590	arg1	infants					592:598	VPT infants	588:598	VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial	588:688	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	3	64	theme	Metagenomic	528:538	arg1	analysis					540:547	Metagenomic analysis	528:547	Metagenomic analysis	528:547	Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial.					
35565868	2	65	theme	infant	358:363	arg1	formula					365:371	an infant formula	355:371	an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP)	355:462	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	2	66	theme	study	318:322	arg1	aim					306:308	The aim	302:308	The aim of this study	302:322	The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota.					
35565868	6	67	from	abundance	1055:1063	arg1	group					1096:1100	the test group	1087:1100	the test group	1087:1100	After the 4-week intervention, the abundance of Bifidobacterium in the test group was significantly increased.					
35565868	1	68	theme	environmental	279:291	arg1	factors					293:299	physiological, dietary, medical, and environmental factors	242:299	physiological, dietary, medical, and environmental factors	242:299	Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors.					
35565868	7	69	dep	found	1134:1138	arg1	enriched					1350:1357	enriched	1350:1357	enriched	1350:1357	We found two GBMs (quinolinic acid synthesis and kynurenine degradation) and four GMMs (glutamine degradation, glyoxylate bypass, dissimilatory nitrate reduction, and preparatory phase of glycolysis) were significantly enriched in the test group, respectively.					
35565868	5	70	theme	test	986:989	arg1	group					991:995	the test group	982:995	the test group	982:995	Enterococcus faecium, Escherichia coli, Klebsiella aerogenes, and Klebsiella pneumoniae were dominant species in both the test group and the control group.					
37127106	0	0	theme	carbon	88:93	arg1	properties					61:70	the surface properties	49:70	the surface properties of hydrothermal carbon	49:93	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	5	1	theme	methylene	1188:1196	arg1	sorption					1176:1183	the sorption	1172:1183	the sorption of methylene blue (MB) on the hydrochar materials	1172:1233	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	4	2	theme	functional	731:740	arg1	hydrochar					618:626	The hydrochar	614:626	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si)	614:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	2	theme	functional	731:740	arg1	size					858:861	suitable pore size	844:861	suitable pore size (1.90 nm-1.93 nm)	844:879	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	2	theme	functional	731:740	arg1	groups					742:747	most enriched functional groups	717:747	most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g)	717:838	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	2	theme	functional	731:740	arg1	sorbent					886:892	a sorbent	884:892	a sorbent riched in hemicellulose	884:916	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	7	3	theme	pore	1668:1671	arg1	procedure					1683:1691	the pore diffusion procedure	1664:1691	the pore diffusion procedure	1664:1691	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	0	4	theme	hydrothermal	75:86	arg1	carbon					88:93	hydrothermal carbon	75:93	hydrothermal carbon	75:93	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	5	5	theme	blue	1198:1201	arg1	methylene					1188:1196	methylene blue	1188:1201	methylene blue (MB)	1188:1206	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	5	theme	blue	1198:1201	arg1	MB					1204:1205	MB	1204:1205	MB	1204:1205	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	6	6	theme	membrane	1327:1334	arg1	90 min					1312:1317	90 min	1312:1317	90 min (liquid membrane diffusion)	1312:1345	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	6	theme	membrane	1327:1334	arg1	diffusion					1336:1344	liquid membrane diffusion	1320:1344	liquid membrane diffusion	1320:1344	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	4	7	theme	pore	853:856	arg1	hydrochar					618:626	The hydrochar	614:626	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si)	614:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	7	theme	pore	853:856	arg1	1.90 nm-1.93 nm					864:878	1.90 nm-1.93 nm	864:878	1.90 nm-1.93 nm	864:878	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	7	theme	pore	853:856	arg1	size					858:861	suitable pore size	844:861	suitable pore size (1.90 nm-1.93 nm)	844:879	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	7	theme	pore	853:856	arg1	groups					742:747	most enriched functional groups	717:747	most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g)	717:838	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	7	theme	pore	853:856	arg1	sorbent					886:892	a sorbent	884:892	a sorbent riched in hemicellulose	884:916	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	9	8	theme	composites	1939:1948	arg1	reusability					1914:1924	reusability	1914:1924	reusability	1914:1924	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	9	8	theme	composites	1939:1948	arg1	stability					1900:1908	high stability	1895:1908	high stability	1895:1908	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	7	9	theme	carboxyl	1586:1593	arg1	groups					1595:1600	carboxyl groups	1586:1600	carboxyl groups on the hemicellulose	1586:1621	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	3	10	from	experiment	425:434	arg1	procedure					476:484	a one-pot hydrothermal carbonization procedure	439:484	a one-pot hydrothermal carbonization procedure	439:484	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	6	11	theme	liquid	1320:1325	arg1	90 min					1312:1317	90 min	1312:1317	90 min (liquid membrane diffusion)	1312:1345	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	11	theme	liquid	1320:1325	arg1	diffusion					1336:1344	liquid membrane diffusion	1320:1344	liquid membrane diffusion	1320:1344	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	3	12	theme	microporous	566:576	arg1	structure					578:586	microporous structure	566:586	microporous structure	566:586	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	4	13	dep	groups	742:747	arg1	carboxyl = 11.48 μmol/g					750:772	carboxyl = 11.48 μmol/g	750:772	carboxyl = 11.48 μmol/g	750:772	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	13	dep	groups	742:747	arg1	hydroxyl = 52.98 μmol/g					784:806	phenolic hydroxyl = 52.98 μmol/g	775:806	phenolic hydroxyl = 52.98 μmol/g	775:806	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	13	dep	groups	742:747	arg1	groups = 46.52 μmol/g					817:837	lactone groups = 46.52 μmol/g	809:837	lactone groups = 46.52 μmol/g	809:837	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	8	14	from	CEC	1707:1709	arg1	hemicellulose					1765:1777	hemicellulose	1765:1777	hemicellulose	1765:1777	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	8	14	from	CEC	1707:1709	arg1	cellulose					1751:1759	cellulose	1751:1759	cellulose	1751:1759	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	6	15	theme	hydrochar	1256:1264	arg1	materials					1266:1274	all hydrochar materials	1252:1274	all hydrochar materials	1252:1274	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	7	16	theme	correlation	1477:1487	arg1	analysis					1489:1496	Pearson's correlation analysis	1467:1496	Pearson's correlation analysis	1467:1496	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	8	17	theme	phenolic	1719:1726	arg1	groups					1737:1742	the phenolic hydroxyl groups	1715:1742	the phenolic hydroxyl groups on the cellulose and hemicellulose	1715:1777	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	9	18	theme	HBC-R2/Si	1929:1937	arg1	composites					1939:1948	HBC-R2/Si composites	1929:1948	HBC-R2/Si composites	1929:1948	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	4	19	theme	suitable	844:851	arg1	hydrochar					618:626	The hydrochar	614:626	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si)	614:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	19	theme	suitable	844:851	arg1	1.90 nm-1.93 nm					864:878	1.90 nm-1.93 nm	864:878	1.90 nm-1.93 nm	864:878	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	19	theme	suitable	844:851	arg1	size					858:861	suitable pore size	844:861	suitable pore size (1.90 nm-1.93 nm)	844:879	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	19	theme	suitable	844:851	arg1	groups					742:747	most enriched functional groups	717:747	most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g)	717:838	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	19	theme	suitable	844:851	arg1	sorbent					886:892	a sorbent	884:892	a sorbent riched in hemicellulose	884:916	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	3	20	theme	one-pot	441:447	arg1	procedure					476:484	a one-pot hydrothermal carbonization procedure	439:484	a one-pot hydrothermal carbonization procedure	439:484	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	3	21	from	recirculation	389:401	arg1	procedure					476:484	a one-pot hydrothermal carbonization procedure	439:484	a one-pot hydrothermal carbonization procedure	439:484	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	9	22	theme	sorption/desorption	1854:1872	arg1	cycles					1874:1879	Three consecutive sorption/desorption cycles	1836:1879	Three consecutive sorption/desorption cycles	1836:1879	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	2	23	theme	chemical	290:297	arg1	structure					299:307	their own physical and chemical structure	267:307	their own physical and chemical structure	267:307	Components interact with their own physical and chemical structure, making it harsh to understand the conversion as a whole.					
37127106	1	24	theme	chemistry	184:192	arg1	complexity					166:175	The complexity	162:175	The complexity of the chemistry behind the hydrothermal conversion	162:227	The complexity of the chemistry behind the hydrothermal conversion is enormous.					
37127106	1	24	theme	chemistry	184:192	arg1	enormous					232:239	enormous	232:239	enormous	232:239	The complexity of the chemistry behind the hydrothermal conversion is enormous.					
37127106	6	25	theme	liquid	1402:1407	arg1	step					1461:1464	the predominant rate-limiting step	1431:1464	the predominant rate-limiting step	1431:1464	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	25	theme	liquid	1402:1407	arg1	diffusion					1418:1426	liquid membrane diffusion	1402:1426	liquid membrane diffusion	1402:1426	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	7	26	from	capacity	1555:1562	arg1	hemicellulose					1609:1621	the hemicellulose	1605:1621	the hemicellulose	1605:1621	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	3	27	theme	hydrochar	595:603	arg1	surface					605:611	the hydrochar surface	591:611	the hydrochar surface	591:611	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	8	28	theme	hydroxyl	1728:1735	arg1	groups					1737:1742	the phenolic hydroxyl groups	1715:1742	the phenolic hydroxyl groups on the cellulose and hemicellulose	1715:1777	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	0	29	theme	Directional	0:10	arg1	regulation					12:21	Directional regulation	0:21	Directional regulation	0:21	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	5	30	theme	hydrochar	1215:1223	arg1	materials					1225:1233	the hydrochar materials	1211:1233	the hydrochar materials	1211:1233	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	6	31	theme	MB	1294:1295	arg1	removal					1297:1303	25% MB removal	1290:1303	25% MB removal	1290:1303	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	3	32	theme	surface	605:611	arg1	groups					555:560	the functional groups	540:560	the functional groups	540:560	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	3	32	theme	surface	605:611	arg1	structure					578:586	microporous structure	566:586	microporous structure	566:586	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	3	32	theme	surface	605:611	arg1	surface					605:611	the hydrochar surface	591:611	the hydrochar surface	591:611	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	5	33	dep	membranes	1087:1095	arg1	membranes					1087:1095	membranes	1087:1095	membranes	1087:1095	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	33	dep	membranes	1087:1095	arg1	diffusion					1111:1119	diffusion	1111:1119	diffusion	1111:1119	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	33	dep	membranes	1087:1095	arg1	diffusion					1127:1135	pore diffusion	1122:1135	pore diffusion	1122:1135	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	33	dep	membranes	1087:1095	arg1	sorption					1150:1157	surface sorption	1142:1157	surface sorption	1142:1157	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	0	34	theme	mechanism	27:35	arg1	analysis					37:44	mechanism analysis	27:44	mechanism analysis	27:44	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	4	35	theme	phenolic	775:782	arg1	carboxyl = 11.48 μmol/g					750:772	carboxyl = 11.48 μmol/g	750:772	carboxyl = 11.48 μmol/g	750:772	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	35	theme	phenolic	775:782	arg1	hydroxyl = 52.98 μmol/g					784:806	phenolic hydroxyl = 52.98 μmol/g	775:806	phenolic hydroxyl = 52.98 μmol/g	775:806	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	0	36	theme	hydrothermal	124:135	arg1	procedure					151:159	the hydrothermal carbonization procedure	120:159	the hydrothermal carbonization procedure	120:159	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	9	37	dep	stability	1900:1908	arg1	the					1891:1893	the	1891:1893	the	1891:1893	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	4	38	theme	lactone	809:815	arg1	carboxyl = 11.48 μmol/g					750:772	carboxyl = 11.48 μmol/g	750:772	carboxyl = 11.48 μmol/g	750:772	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	38	theme	lactone	809:815	arg1	groups = 46.52 μmol/g					817:837	lactone groups = 46.52 μmol/g	809:837	lactone groups = 46.52 μmol/g	809:837	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	5	39	theme	Weber	1033:1037	arg1	models					1063:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	1	40	theme	hydrothermal	205:216	arg1	conversion					218:227	the hydrothermal conversion	201:227	the hydrothermal conversion	201:227	The complexity of the chemistry behind the hydrothermal conversion is enormous.					
37127106	3	41	theme	six-water	379:387	arg1	recirculation					389:401	the six-water recirculation and loading nano SiO2 experiment	375:434	recirculation	389:401	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	5	42	theme	pseudo-second-order	1012:1030	arg1	models					1063:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	4	43	theme	enriched	722:729	arg1	hydrochar					618:626	The hydrochar	614:626	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si)	614:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	43	theme	enriched	722:729	arg1	size					858:861	suitable pore size	844:861	suitable pore size (1.90 nm-1.93 nm)	844:879	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	43	theme	enriched	722:729	arg1	groups					742:747	most enriched functional groups	717:747	most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g)	717:838	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	43	theme	enriched	722:729	arg1	sorbent					886:892	a sorbent	884:892	a sorbent riched in hemicellulose	884:916	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	7	44	theme	diffusion	1673:1681	arg1	procedure					1683:1691	the pore diffusion procedure	1664:1691	the pore diffusion procedure	1664:1691	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	5	45	theme	sorption	923:930	arg1	kinetics					932:939	The sorption kinetics	919:939	The sorption kinetics (equilibrium reached ≈ 480 min)	919:971	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	45	theme	sorption	923:930	arg1	reached ≈ 480 min					954:970	equilibrium reached ≈ 480 min	942:970	equilibrium reached ≈ 480 min	942:970	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	3	46	theme	SiO2	420:423	arg1	experiment					425:434	the six-water recirculation and loading nano SiO2 experiment	375:434	experiment	425:434	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	7	47	theme	pore	1571:1574	arg1	size					1576:1579	pore size	1571:1579	pore size	1571:1579	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	6	48	theme	%	1292:1292	arg1	removal					1297:1303	25% MB removal	1290:1303	25% MB removal	1290:1303	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	3	49	theme	carbonization	462:474	arg1	procedure					476:484	a one-pot hydrothermal carbonization procedure	439:484	a one-pot hydrothermal carbonization procedure	439:484	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	6	50	theme	rate-limiting	1447:1459	arg1	step					1461:1464	the predominant rate-limiting step	1431:1464	the predominant rate-limiting step	1431:1464	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	50	theme	rate-limiting	1447:1459	arg1	diffusion					1418:1426	liquid membrane diffusion	1402:1426	liquid membrane diffusion	1402:1426	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	7	51	theme	sorption	1634:1641	arg1	capacity					1643:1650	the sorption capacity	1630:1650	the sorption capacity	1630:1650	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	0	52	theme	carbonization	137:149	arg1	procedure					151:159	the hydrothermal carbonization procedure	120:159	the hydrothermal carbonization procedure	120:159	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	5	53	theme	surface	1142:1148	arg1	membranes					1087:1095	membranes	1087:1095	membranes	1087:1095	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	53	theme	surface	1142:1148	arg1	sorption					1150:1157	surface sorption	1142:1157	surface sorption	1142:1157	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	6	54	theme	25	1290:1291	arg1	%					1292:1292	%	1292:1292	%	1292:1292	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	4	55	theme	loading	674:680	arg1	HBC-R2/Si					693:701	HBC-R2/Si	693:701	HBC-R2/Si	693:701	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	55	theme	loading	674:680	arg1	nano-SiO2					682:690	loading nano-SiO2	674:690	loading nano-SiO2 (HBC-R2/Si)	674:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	3	56	theme	loading	407:413	arg1	experiment					425:434	the six-water recirculation and loading nano SiO2 experiment	375:434	experiment	425:434	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	5	57	theme	equilibrium	942:952	arg1	kinetics					932:939	The sorption kinetics	919:939	The sorption kinetics (equilibrium reached ≈ 480 min)	919:971	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	57	theme	equilibrium	942:952	arg1	reached ≈ 480 min					954:970	equilibrium reached ≈ 480 min	942:970	equilibrium reached ≈ 480 min	942:970	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	7	58	from	groups	1595:1600	arg1	hemicellulose					1609:1621	the hemicellulose	1605:1621	the hemicellulose	1605:1621	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	0	59	theme	properties	61:70	arg1	regulation					12:21	Directional regulation	0:21	Directional regulation	0:21	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	0	59	theme	properties	61:70	arg1	analysis					37:44	mechanism analysis	27:44	mechanism analysis	27:44	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	5	60	from	sorption	1176:1183	arg1	materials					1225:1233	the hydrochar materials	1211:1233	the hydrochar materials	1211:1233	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	3	61	theme	nano	415:418	arg1	experiment					425:434	the six-water recirculation and loading nano SiO2 experiment	375:434	experiment	425:434	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	6	62	theme	predominant	1435:1445	arg1	step					1461:1464	the predominant rate-limiting step	1431:1464	the predominant rate-limiting step	1431:1464	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	62	theme	predominant	1435:1445	arg1	diffusion					1418:1426	liquid membrane diffusion	1402:1426	liquid membrane diffusion	1402:1426	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	7	63	from	size	1576:1579	arg1	hemicellulose					1609:1621	the hemicellulose	1605:1621	the hemicellulose	1605:1621	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	8	64	theme	sorption	1790:1797	arg1	rate					1799:1802	the sorption rate	1786:1802	the sorption rate	1786:1802	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	9	65	theme	high	1895:1898	arg1	stability					1900:1908	high stability	1895:1908	high stability	1895:1908	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	6	66	theme	membrane	1409:1416	arg1	step					1461:1464	the predominant rate-limiting step	1431:1464	the predominant rate-limiting step	1431:1464	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	6	66	theme	membrane	1409:1416	arg1	diffusion					1418:1426	liquid membrane diffusion	1402:1426	liquid membrane diffusion	1402:1426	Simultaneously, all hydrochar materials achieved over 25% MB removal within 90 min (liquid membrane diffusion) and over 40% for HBC-R2 and HBC-R2/Si, suggesting that liquid membrane diffusion is the predominant rate-limiting step.					
37127106	7	67	theme	cation	1539:1544	arg1	capacity					1555:1562	the cation exchange capacity	1535:1562	the cation exchange capacity (CEC)	1535:1568	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	7	67	theme	cation	1539:1544	arg1	CEC					1565:1567	CEC	1565:1567	CEC	1565:1567	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	5	68	theme	Elovich	1055:1061	arg1	models					1063:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	the pseudo-second-order, Weber and Morris, and Elovich models	1008:1068	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	69	theme	pore	1122:1125	arg1	membranes					1087:1095	membranes	1087:1095	membranes	1087:1095	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	5	69	theme	pore	1122:1125	arg1	diffusion					1127:1135	pore diffusion	1122:1135	pore diffusion	1122:1135	The sorption kinetics (equilibrium reached ≈ 480 min) are approximately evenly fitted by the pseudo-second-order, Weber and Morris, and Elovich models, indicating that membranes and particles diffusion, pore diffusion, and surface sorption coexisted in the sorption of methylene blue (MB) on the hydrochar materials.					
37127106	2	70	theme	physical	277:284	arg1	structure					299:307	their own physical and chemical structure	267:307	their own physical and chemical structure	267:307	Components interact with their own physical and chemical structure, making it harsh to understand the conversion as a whole.					
37127106	7	71	theme	exchange	1546:1553	arg1	capacity					1555:1562	the cation exchange capacity	1535:1562	the cation exchange capacity (CEC)	1535:1568	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	7	71	theme	exchange	1546:1553	arg1	CEC					1565:1567	CEC	1565:1567	CEC	1565:1567	Pearson's correlation analysis and Mantel's analysis announced that the cation exchange capacity (CEC), pore size, and carboxyl groups on the hemicellulose affect the sorption capacity by limiting the pore diffusion procedure.					
37127106	2	72	theme	own	273:275	arg1	structure					299:307	their own physical and chemical structure	267:307	their own physical and chemical structure	267:307	Components interact with their own physical and chemical structure, making it harsh to understand the conversion as a whole.					
37127106	4	73	theme	most	717:720	arg1	hydrochar					618:626	The hydrochar	614:626	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si)	614:702	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	73	theme	most	717:720	arg1	size					858:861	suitable pore size	844:861	suitable pore size (1.90 nm-1.93 nm)	844:879	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	73	theme	most	717:720	arg1	groups					742:747	most enriched functional groups	717:747	most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g)	717:838	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	4	73	theme	most	717:720	arg1	sorbent					886:892	a sorbent	884:892	a sorbent riched in hemicellulose	884:916	The hydrochar prepared by the second circulating liquid and loading nano-SiO2 (HBC-R2/Si) was equipped most enriched functional groups (carboxyl = 11.48 μmol/g, phenolic hydroxyl = 52.98 μmol/g, lactone groups = 46.52 μmol/g) and suitable pore size (1.90 nm-1.93 nm) as a sorbent riched in hemicellulose.					
37127106	3	74	theme	hydrothermal	449:460	arg1	procedure					476:484	a one-pot hydrothermal carbonization procedure	439:484	a one-pot hydrothermal carbonization procedure	439:484	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	8	75	from	groups	1737:1742	arg1	hemicellulose					1765:1777	hemicellulose	1765:1777	hemicellulose	1765:1777	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	8	75	from	groups	1737:1742	arg1	cellulose					1751:1759	cellulose	1751:1759	cellulose	1751:1759	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	0	76	theme	surface	53:59	arg1	properties					61:70	the surface properties	49:70	the surface properties of hydrothermal carbon	49:93	Directional regulation and mechanism analysis of the surface properties of hydrothermal carbon by circulating liquid in the hydrothermal carbonization procedure.					
37127106	9	77	theme	consecutive	1842:1852	arg1	cycles					1874:1879	Three consecutive sorption/desorption cycles	1836:1879	Three consecutive sorption/desorption cycles	1836:1879	Three consecutive sorption/desorption cycles confirmed the high stability and reusability of HBC-R2/Si composites.					
37127106	8	78	theme	membrane	1816:1823	arg1	diffusion					1825:1833	membrane diffusion	1816:1833	membrane diffusion	1816:1833	However, the CEC and the phenolic hydroxyl groups on the cellulose and hemicellulose affect the sorption rate by limiting membrane diffusion.					
37127106	3	79	theme	functional	544:553	arg1	groups					555:560	the functional groups	540:560	the functional groups	540:560	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
37127106	3	79	theme	functional	544:553	arg1	surface					605:611	the hydrochar surface	591:611	the hydrochar surface	591:611	Herein, the six-water recirculation and loading nano SiO2 experiment in a one-pot hydrothermal carbonization procedure was designed to elucidate the mechanism of regulating the functional groups and microporous structure of the hydrochar surface.					
36650807	5	0	theme	based	713:717	arg1	models					719:724	Malkin and Kulichikin (1996) [1] based models	680:724	Malkin and Kulichikin (1996) [1] based models	680:724	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	9	1	with	principle	1025:1033	arg1	variance					1073:1080	heteroscedastic prediction error variance	1040:1080	heteroscedastic prediction error variance	1040:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	13	2	theme	variance	1657:1664	arg1	model					1666:1670	the error variance model	1647:1670	the error variance model	1647:1670	In both cases we prove the error variance model is heteroskedastic and the model is identifiable.					
36650807	13	2	theme	variance	1657:1664	arg1	heteroskedastic					1675:1689	heteroskedastic	1675:1689	heteroskedastic	1675:1689	In both cases we prove the error variance model is heteroskedastic and the model is identifiable.					
36650807	8	3	theme	dynamical	909:917	arg1	data					931:934	dynamical rheological data	909:934	dynamical rheological data	909:934	We use dynamical rheological data to fit the reaction models.					
36650807	1	4	theme	interest	147:154	arg1	modeling					95:102	The modeling	91:102	The modeling of polymeric reactions	91:125	The modeling of polymeric reactions is a topic of large interest.					
36650807	1	4	theme	interest	147:154	arg1	topic					132:136	a topic	130:136	a topic of large interest	130:154	The modeling of polymeric reactions is a topic of large interest.					
36650807	7	5	theme	agent-based	834:844	arg1	reaction					859:866	the agent-based crosslinking reaction	830:866	the agent-based crosslinking reaction promoted by genipin	830:886	Then, the agent-based crosslinking reaction promoted by genipin is addressed.					
36650807	4	6	theme	elastic	561:567	arg1	modulus					569:575	the elastic modulus	557:575	the elastic modulus of the mixture	557:590	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	0	7	theme	systems	82:88	arg1	kinetics					55:62	the gelation kinetics	42:62	the gelation kinetics of chitosan-based systems	42:88	Using rheological monitoring to determine the gelation kinetics of chitosan-based systems.					
36650807	4	8	theme	rheological	503:513	arg1	behavior					515:522	the rheological behavior	499:522	the rheological behavior of the reacting mass	499:543	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	9	9	theme	Likelihood	1014:1023	arg1	principle					1025:1033	Maximum Likelihood principle	1006:1033	Maximum Likelihood principle with heteroscedastic prediction error variance	1006:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	12	10	theme	first	1527:1531	arg1	order					1533:1537	first order	1527:1537	first order	1527:1537	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	5	11	theme	Kulichikin	691:700	arg1	models					719:724	Malkin and Kulichikin (1996) [1] based models	680:724	Malkin and Kulichikin (1996) [1] based models	680:724	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	8	12	theme	reaction	947:954	arg1	models					956:961	the reaction models	943:961	the reaction models	943:961	We use dynamical rheological data to fit the reaction models.					
36650807	9	13	theme	sequential	1161:1170	arg1	approach					1172:1179	a sequential approach	1159:1179	a sequential approach	1159:1179	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	10	14	theme	confidence	1193:1202	arg1	regions					1204:1210	Parametric confidence regions	1182:1210	Parametric confidence regions	1182:1210	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
36650807	12	15	theme	reaction	1432:1439	arg1	order					1441:1445	The reaction order	1428:1445	The reaction order obtained for self-crosslinking kinetics	1428:1485	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	12	15	theme	reaction	1432:1439	arg1	±					1497:1497	1.3375 ±	1490:1497	1.3375 ± (0.0151) - approximately of first order -	1490:1539	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	12	16	dep	order	1616:1620	arg1	approximately					1592:1604	approximately	1592:1604	approximately	1592:1604	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	10	17	theme	matrix	1274:1279	arg1	approximation					1242:1254	the linear approximation	1231:1254	the linear approximation of the covariance matrix at the optimum	1231:1294	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
36650807	3	18	theme	entities	351:358	arg1	composition					328:338	The composition	324:338	The composition of polymer entities during the reaction	324:378	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	4	19	theme	rheological	601:611	arg1	degree					613:618	the rheological degree	597:618	the rheological degree of conversion	597:632	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	9	20	theme	heteroscedastic	1040:1054	arg1	error					1067:1071	heteroscedastic prediction error	1040:1071	heteroscedastic prediction error variance	1040:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	10	21	theme	Parametric	1182:1191	arg1	regions					1204:1210	Parametric confidence regions	1182:1210	Parametric confidence regions	1182:1210	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
36650807	11	22	used	used	1363:1366	arg2	matrix					1333:1338	the parameters correlation matrix	1306:1338	the parameters correlation matrix	1306:1338	Further, the parameters correlation matrix is also determined and used to qualitatively infer about the practical identifiability.					
36650807	9	23	theme	prediction	1056:1065	arg1	error					1067:1071	heteroscedastic prediction error	1040:1071	heteroscedastic prediction error variance	1040:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	3	24	theme	good	432:435	arg1	measure					437:443	a good measure	430:443	a good measure of the system dynamics	430:466	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	3	24	theme	good	432:435	arg1	concentration					409:421	their concentration	403:421	their concentration	403:421	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	0	25	theme	rheological	6:16	arg1	monitoring					18:27	rheological monitoring	6:27	rheological monitoring	6:27	Using rheological monitoring to determine the gelation kinetics of chitosan-based systems.					
36650807	5	26	theme	[1	709:710	arg1	models					719:724	Malkin and Kulichikin (1996) [1] based models	680:724	Malkin and Kulichikin (1996) [1] based models	680:724	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	9	27	theme	error	1067:1071	arg1	variance					1073:1080	heteroscedastic prediction error variance	1040:1080	heteroscedastic prediction error variance	1040:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	9	28	theme	Maximum	1006:1012	arg1	Likelihood					1014:1023	Maximum Likelihood	1006:1023	Maximum Likelihood principle with heteroscedastic prediction error variance	1006:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	5	29	theme	chitosan	758:765	arg1	crosslinking					742:753	the crosslinking	738:753	the crosslinking of chitosan	738:765	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	14	30	theme	polymer	1776:1782	arg1	systems					1784:1790	other polymer systems	1770:1790	other polymer systems	1770:1790	The approach proposed herein can be extended to other polymer systems.					
36650807	13	31	theme	error	1651:1655	arg1	model					1666:1670	the error variance model	1647:1670	the error variance model	1647:1670	In both cases we prove the error variance model is heteroskedastic and the model is identifiable.					
36650807	13	31	theme	error	1651:1655	arg1	heteroskedastic					1675:1689	heteroskedastic	1675:1689	heteroskedastic	1675:1689	In both cases we prove the error variance model is heteroskedastic and the model is identifiable.					
36650807	12	32	theme	second	1609:1614	arg1	order					1616:1620	second order	1609:1620	second order	1609:1620	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	11	33	theme	parameters	1310:1319	arg1	matrix					1333:1338	the parameters correlation matrix	1306:1338	the parameters correlation matrix	1306:1338	Further, the parameters correlation matrix is also determined and used to qualitatively infer about the practical identifiability.					
36650807	4	34	theme	mass	540:543	arg1	behavior					515:522	the rheological behavior	499:522	the rheological behavior of the reacting mass	499:543	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	10	35	from	optimum	1288:1294	arg1	approximation					1242:1254	the linear approximation	1231:1254	the linear approximation of the covariance matrix at the optimum	1231:1294	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
36650807	2	36	theme	biomaterials	297:308	arg1	applications					310:321	biomaterials applications	297:321	biomaterials applications	297:321	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	11	37	theme	correlation	1321:1331	arg1	matrix					1333:1338	the parameters correlation matrix	1306:1338	the parameters correlation matrix	1306:1338	Further, the parameters correlation matrix is also determined and used to qualitatively infer about the practical identifiability.					
36650807	1	38	theme	polymeric	107:115	arg1	reactions					117:125	polymeric reactions	107:125	polymeric reactions	107:125	The modeling of polymeric reactions is a topic of large interest.					
36650807	3	39	theme	system	452:457	arg1	dynamics					459:466	the system dynamics	448:466	the system dynamics	448:466	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	5	40	theme	Malkin	680:685	arg1	models					719:724	Malkin and Kulichikin (1996) [1] based models	680:724	Malkin and Kulichikin (1996) [1] based models	680:724	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	2	41	theme	agent	230:234	arg1	crosslinking					244:255	hybrid (agent based-) crosslinking	222:255	hybrid (agent based-) crosslinking	222:255	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	12	42	theme	order	1616:1620	arg1	crosslinking					1578:1589	hybrid crosslinking	1571:1589	hybrid crosslinking (approximately of second order)	1571:1621	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	4	43	theme	conversion	623:632	arg1	degree					613:618	the rheological degree	597:618	the rheological degree of conversion	597:632	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	10	44	theme	linear	1235:1240	arg1	approximation					1242:1254	the linear approximation	1231:1254	the linear approximation of the covariance matrix at the optimum	1231:1294	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
36650807	2	45	theme	gelation	161:168	arg1	reactions					170:178	The gelation reactions	157:178	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking	157:255	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	2	45	theme	gelation	161:168	arg1	examples					261:268	examples	261:268	examples with interest	261:282	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	11	46	theme	practical	1401:1409	arg1	identifiability					1411:1425	the practical identifiability	1397:1425	the practical identifiability	1397:1425	Further, the parameters correlation matrix is also determined and used to qualitatively infer about the practical identifiability.					
36650807	12	47	theme	hybrid	1571:1576	arg1	crosslinking					1578:1589	hybrid crosslinking	1571:1589	hybrid crosslinking (approximately of second order)	1571:1621	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	6	48	theme	chitosan	800:807	arg1	self-crosslinking					779:795	the self-crosslinking	775:795	the self-crosslinking of chitosan	775:807	First, the self-crosslinking of chitosan is considered.					
36650807	2	49	theme	hybrid	222:227	arg1	crosslinking					244:255	hybrid (agent based-) crosslinking	222:255	hybrid (agent based-) crosslinking	222:255	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	9	50	theme	Dynamic	1101:1107	arg1	problem					982:988	The model fitting problem	964:988	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance	964:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	9	50	theme	Dynamic	1101:1107	arg1	problem					1122:1128	a Dynamic Optimization problem	1099:1128	a Dynamic Optimization problem	1099:1128	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	1	51	theme	reactions	117:125	arg1	modeling					95:102	The modeling	91:102	The modeling of polymeric reactions	91:125	The modeling of polymeric reactions is a topic of large interest.					
36650807	1	51	theme	reactions	117:125	arg1	topic					132:136	a topic	130:136	a topic of large interest	130:154	The modeling of polymeric reactions is a topic of large interest.					
36650807	0	52	theme	gelation	46:53	arg1	kinetics					55:62	the gelation kinetics	42:62	the gelation kinetics of chitosan-based systems	42:88	Using rheological monitoring to determine the gelation kinetics of chitosan-based systems.					
36650807	4	53	theme	reacting	531:538	arg1	mass					540:543	the reacting mass	527:543	the reacting mass	527:543	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	9	54	theme	Optimization	1109:1120	arg1	problem					982:988	The model fitting problem	964:988	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance	964:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	9	54	theme	Optimization	1109:1120	arg1	problem					1122:1128	a Dynamic Optimization problem	1099:1128	a Dynamic Optimization problem	1099:1128	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	14	55	theme	other	1770:1774	arg1	systems					1784:1790	other polymer systems	1770:1790	other polymer systems	1770:1790	The approach proposed herein can be extended to other polymer systems.					
36650807	9	56	theme	model	968:972	arg1	problem					982:988	The model fitting problem	964:988	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance	964:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	9	56	theme	model	968:972	arg1	problem					1122:1128	a Dynamic Optimization problem	1099:1128	a Dynamic Optimization problem	1099:1128	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	5	57	theme	rheological	656:666	arg1	data					668:671	rheological data	656:671	rheological data	656:671	In this paper we use rheological data to fit Malkin and Kulichikin (1996) [1] based models to describe the crosslinking of chitosan.					
36650807	3	58	theme	dynamics	459:466	arg1	measure					437:443	a good measure	430:443	a good measure of the system dynamics	430:466	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	3	58	theme	dynamics	459:466	arg1	concentration					409:421	their concentration	403:421	their concentration	403:421	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	2	59	from	examples	261:268	arg1	applications					310:321	biomaterials applications	297:321	biomaterials applications	297:321	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	4	60	theme	mixture	584:590	arg1	modulus					569:575	the elastic modulus	557:575	the elastic modulus of the mixture	557:590	One alternative is monitoring the rheological behavior of the reacting mass, and relate the elastic modulus of the mixture with the rheological degree of conversion.					
36650807	7	61	theme	crosslinking	846:857	arg1	reaction					859:866	the agent-based crosslinking reaction	830:866	the agent-based crosslinking reaction promoted by genipin	830:886	Then, the agent-based crosslinking reaction promoted by genipin is addressed.					
36650807	2	62	with	examples	261:268	arg1	interest					275:282	interest	275:282	interest	275:282	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	0	63	theme	chitosan-based	67:80	arg1	systems					82:88	chitosan-based systems	67:88	chitosan-based systems	67:88	Using rheological monitoring to determine the gelation kinetics of chitosan-based systems.					
36650807	9	64	theme	fitting	974:980	arg1	problem					982:988	The model fitting problem	964:988	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance	964:1080	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	9	64	theme	fitting	974:980	arg1	problem					1122:1128	a Dynamic Optimization problem	1099:1128	a Dynamic Optimization problem	1099:1128	The model fitting problem generated using Maximum Likelihood principle with heteroscedastic prediction error variance is formulated as a Dynamic Optimization problem and subsequently solved with a sequential approach.					
36650807	12	65	dep	±	1497:1497	arg1	approximately					1510:1522	approximately	1510:1522	approximately	1510:1522	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	3	66	theme	polymer	343:349	arg1	entities					351:358	polymer entities	343:358	polymer entities	343:358	The composition of polymer entities during the reaction is hard to follow, and their concentration is not a good measure of the system dynamics.					
36650807	12	67	theme	self-crosslinking	1460:1476	arg1	kinetics					1478:1485	self-crosslinking kinetics	1460:1485	self-crosslinking kinetics	1460:1485	The reaction order obtained for self-crosslinking kinetics is 1.3375 ± (0.0151) - approximately of first order -, and is 2.2402 ± (0.0373) for hybrid crosslinking (approximately of second order).					
36650807	2	68	theme	based-	236:241	arg1	crosslinking					244:255	hybrid (agent based-) crosslinking	222:255	hybrid (agent based-) crosslinking	222:255	The gelation reactions that may result from self-crosslinking or hybrid (agent based-) crosslinking are examples with interest specially in biomaterials applications.					
36650807	8	69	theme	rheological	919:929	arg1	data					931:934	dynamical rheological data	909:934	dynamical rheological data	909:934	We use dynamical rheological data to fit the reaction models.					
36650807	1	70	theme	large	141:145	arg1	interest					147:154	large interest	141:154	large interest	141:154	The modeling of polymeric reactions is a topic of large interest.					
36650807	10	71	theme	covariance	1263:1272	arg1	matrix					1274:1279	the covariance matrix	1259:1279	the covariance matrix	1259:1279	Parametric confidence regions are computed using the linear approximation of the covariance matrix at the optimum.					
35841754	1	0	theme	organic	162:168	arg1	OATP					202:205	OATP	202:205	OATP	202:205	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	1	0	theme	organic	162:168	arg1	polypeptide					189:199	organic anion-transporting polypeptide	162:199	organic anion-transporting polypeptide (OATP) 1A2	162:210	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	6	1	theme	Ala187Thr	1079:1087	arg1	variant					1089:1095	the Ala187Thr variant	1075:1095	the Ala187Thr variant	1075:1095	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	1	2	theme	anion-transporting	170:187	arg1	OATP					202:205	OATP	202:205	OATP	202:205	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	1	2	theme	anion-transporting	170:187	arg1	polypeptide					189:199	organic anion-transporting polypeptide	162:199	organic anion-transporting polypeptide (OATP) 1A2	162:210	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	5	3	theme	concentration-dependent	935:957	arg1	manner					959:964	a concentration-dependent manner	933:964	a concentration-dependent manner	933:964	Naringin, narirutin, and prunin inhibited FEX (0.3 μM) uptake by all of the examined OATP1A2 variants in a concentration-dependent manner.					
35841754	1	4	with	variants	150:157	arg1	activity					235:242	altered transport activity	217:242	altered transport activity	217:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	3	5	theme	moieties	529:536	arg1	number					513:518	the number	509:518	the number of sugar moieties	509:536	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	4	6	theme	monosaccharide	642:655	arg1	prunin					667:672	its monosaccharide glycoside prunin	638:672	its monosaccharide glycoside prunin	638:672	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	10	7	gly	glycosylation	1537:1549	arg1	naringenin					1554:1563	naringenin	1554:1563	naringenin	1554:1563	Moreover, greater glycosylation of naringenin reduces its inhibitory potency against OATP1A2.					
35841754	3	8	dep	such	501:504	arg1	as					506:507	as	506:507	as	506:507	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	5	9	theme	OATP1A2	913:919	arg1	variants					921:928	the examined OATP1A2 variants	900:928	the examined OATP1A2 variants	900:928	Naringin, narirutin, and prunin inhibited FEX (0.3 μM) uptake by all of the examined OATP1A2 variants in a concentration-dependent manner.					
35841754	4	10	theme	disaccharide	683:694	arg1	naringin					707:714	naringin	707:714	naringin	707:714	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	10	theme	disaccharide	683:694	arg1	glycosides					696:705	its disaccharide glycosides naringin and narirutin	679:728	its disaccharide glycosides naringin and narirutin	679:728	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	10	theme	disaccharide	683:694	arg1	narirutin					720:728	narirutin	720:728	narirutin	720:728	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	3	11	theme	molecular	480:488	arg1	structure					490:498	their molecular structure	474:498	their molecular structure	474:498	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	0	12	theme	genetic	109:115	arg1	variants					117:124	OATP1A2 genetic variants	101:124	OATP1A2 genetic variants	101:124	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	4	13	theme	fexofenadine	733:744	arg1	uptake					752:757	fexofenadine (FEX) uptake	733:757	fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	733:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	14	theme	OATP1A2	762:768	arg1	variants					770:777	OATP1A2 variants	762:777	OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	762:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	14	theme	OATP1A2	762:768	arg1	Ala187Thr					801:809	Ala187Thr	801:809	Ala187Thr	801:809	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	14	theme	OATP1A2	762:768	arg1	Thr668Ser					816:824	Thr668Ser	816:824	Thr668Ser	816:824	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	14	theme	OATP1A2	762:768	arg1	Asn128Tyr					790:798	Asn128Tyr	790:798	Asn128Tyr	790:798	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	6	15	theme	inhibition	1010:1019	arg1	Ki					1032:1033	Ki	1032:1033	Ki	1032:1033	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	6	15	theme	inhibition	1010:1019	arg1	constants					1021:1029	the inhibition constants	1006:1029	the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant	1006:1095	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	1	16	theme	polypeptide	189:199	arg1	1A2					208:210	organic anion-transporting polypeptide (OATP) 1A2	162:210	organic anion-transporting polypeptide (OATP) 1A2	162:210	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	0	17	theme	OATP1A2	101:107	arg1	variants					117:124	OATP1A2 genetic variants	101:124	OATP1A2 genetic variants	101:124	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	3	18	from	effects	393:399	arg1	variants					412:419	OATP1A2 variants	404:419	OATP1A2 variants	404:419	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	6	19	theme	narirutin	1049:1057	arg1	Ki					1032:1033	Ki	1032:1033	Ki	1032:1033	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	6	19	theme	narirutin	1049:1057	arg1	constants					1021:1029	the inhibition constants	1006:1029	the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant	1006:1095	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	3	20	theme	sugar	523:527	arg1	moieties					529:536	sugar moieties	523:536	sugar moieties	523:536	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	4	21	dep	variants	770:777	arg1	variants					770:777	OATP1A2 variants	762:777	OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	762:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	21	dep	variants	770:777	arg1	Ala187Thr					801:809	Ala187Thr	801:809	Ala187Thr	801:809	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	21	dep	variants	770:777	arg1	Thr668Ser					816:824	Thr668Ser	816:824	Thr668Ser	816:824	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	21	dep	variants	770:777	arg1	Asn128Tyr					790:798	Asn128Tyr	790:798	Asn128Tyr	790:798	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	5	22	theme	FEX	870:872	arg1	uptake					883:888	FEX (0.3 μM) uptake	870:888	FEX (0.3 μM) uptake	870:888	Naringin, narirutin, and prunin inhibited FEX (0.3 μM) uptake by all of the examined OATP1A2 variants in a concentration-dependent manner.					
35841754	10	23	theme	naringenin	1554:1563	arg1	glycosylation					1537:1549	greater glycosylation	1529:1549	greater glycosylation of naringenin	1529:1563	Moreover, greater glycosylation of naringenin reduces its inhibitory potency against OATP1A2.					
35841754	10	24	theme	greater	1529:1535	arg1	glycosylation					1537:1549	greater glycosylation	1529:1549	greater glycosylation of naringenin	1529:1563	Moreover, greater glycosylation of naringenin reduces its inhibitory potency against OATP1A2.					
35841754	3	25	theme	inhibitory	548:557	arg1	potency					559:565	their inhibitory potency	542:565	their inhibitory potency	542:565	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	4	26	theme	prunin	667:672	arg1	effects					615:621	the inhibitory effects	600:621	the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	600:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	8	27	theme	glycoside > disaccharide	1366:1389	arg1	glycosides					1391:1400	aglycone > monosaccharide glycoside > disaccharide glycosides	1340:1400	aglycone > monosaccharide glycoside > disaccharide glycosides	1340:1400	The order of inhibitory potency was as follows for all variants: aglycone > monosaccharide glycoside > disaccharide glycosides.					
35841754	4	28	theme	glycoside	657:665	arg1	prunin					667:672	its monosaccharide glycoside prunin	638:672	its monosaccharide glycoside prunin	638:672	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	0	29	theme	inhibitory	18:27	arg1	properties					29:38	the inhibitory properties	14:38	the inhibitory properties of the fruit component naringenin	14:72	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	4	30	theme	FEX	747:749	arg1	uptake					752:757	fexofenadine (FEX) uptake	733:757	fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	733:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	1	31	theme	1A2	208:210	arg1	variants					150:157	Non-synonymous genetic variants	127:157	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity	127:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	3	32	theme	inhibitory	382:391	arg1	effects					393:399	their inhibitory effects	376:399	their inhibitory effects on OATP1A2 variants	376:419	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	8	33	theme	potency	1299:1305	arg1	order					1279:1283	The order	1275:1283	The order of inhibitory potency	1275:1305	The order of inhibitory potency was as follows for all variants: aglycone > monosaccharide glycoside > disaccharide glycosides.					
35841754	4	34	dep	glycosides	696:705	arg1	naringin					707:714	naringin	707:714	naringin	707:714	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	34	dep	glycosides	696:705	arg1	glycosides					696:705	its disaccharide glycosides naringin and narirutin	679:728	its disaccharide glycosides naringin and narirutin	679:728	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	4	34	dep	glycosides	696:705	arg1	narirutin					720:728	narirutin	720:728	narirutin	720:728	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	5	35	theme	0.3 μM	875:880	arg1	uptake					883:888	FEX (0.3 μM) uptake	870:888	FEX (0.3 μM) uptake	870:888	Naringin, narirutin, and prunin inhibited FEX (0.3 μM) uptake by all of the examined OATP1A2 variants in a concentration-dependent manner.					
35841754	3	36	contain	has	453:455	arg1	effects					393:399	their inhibitory effects	376:399	their inhibitory effects on OATP1A2 variants	376:419	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	3	36	contain	has	453:455	arg2	influence					461:469	the influence	457:469	the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency	457:565	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	4	37	from	effects	615:621	arg1	uptake					752:757	fexofenadine (FEX) uptake	733:757	fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	733:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	1	38	theme	altered	217:223	arg1	activity					235:242	altered transport activity	217:242	altered transport activity	217:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	0	39	theme	properties	29:38	arg1	Comparison					0:9	Comparison	0:9	Comparison of the inhibitory properties of the fruit component naringenin	0:72	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	0	39	theme	properties	29:38	arg1	glycosides					82:91	its glycosides	78:91	its glycosides against OATP1A2 genetic variants	78:124	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	10	40	theme	inhibitory	1577:1586	arg1	potency					1588:1594	its inhibitory potency	1573:1594	its inhibitory potency against OATP1A2	1573:1610	Moreover, greater glycosylation of naringenin reduces its inhibitory potency against OATP1A2.					
35841754	1	41	theme	transport	225:233	arg1	activity					235:242	altered transport activity	217:242	altered transport activity	217:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	3	42	theme	OATP1A2	404:410	arg1	variants					412:419	OATP1A2 variants	404:419	OATP1A2 variants	404:419	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	2	43	located	found	300:304	arg2	narirutin					279:287	narirutin	279:287	narirutin	279:287	Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2.					
35841754	2	43	located	found	300:304	arg1	grapefruit					309:318	grapefruit	309:318	grapefruit	309:318	Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2.					
35841754	2	43	located	found	300:304	arg2	Naringin					266:273	Naringin	266:273	Naringin	266:273	Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2.					
35841754	2	43	located	found	300:304	arg2	naringenin					339:348	their aglycon naringenin	325:348	their aglycon naringenin	325:348	Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2.					
35841754	0	44	theme	component	53:61	arg1	naringenin					63:72	the fruit component naringenin	43:72	the fruit component naringenin	43:72	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	8	45	theme	aglycone > monosaccharide	1340:1364	arg1	glycosides					1391:1400	aglycone > monosaccharide glycoside > disaccharide glycosides	1340:1400	aglycone > monosaccharide glycoside > disaccharide glycosides	1340:1400	The order of inhibitory potency was as follows for all variants: aglycone > monosaccharide glycoside > disaccharide glycosides.					
35841754	3	46	theme	structure	490:498	arg1	influence					461:469	the influence	457:469	the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency	457:565	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	3	47	from	influence	461:469	arg1	potency					559:565	their inhibitory potency	542:565	their inhibitory potency	542:565	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	4	48	theme	glycosides	696:705	arg1	effects					615:621	the inhibitory effects	600:621	the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	600:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	1	49	theme	Non-synonymous	127:140	arg1	variants					150:157	Non-synonymous genetic variants	127:157	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity	127:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	8	50	theme	inhibitory	1288:1297	arg1	potency					1299:1305	inhibitory potency	1288:1305	inhibitory potency	1288:1305	The order of inhibitory potency was as follows for all variants: aglycone > monosaccharide glycoside > disaccharide glycosides.					
35841754	5	51	theme	examined	904:911	arg1	variants					921:928	the examined OATP1A2 variants	900:928	the examined OATP1A2 variants	900:928	Naringin, narirutin, and prunin inhibited FEX (0.3 μM) uptake by all of the examined OATP1A2 variants in a concentration-dependent manner.					
35841754	1	52	theme	genetic	142:148	arg1	variants					150:157	Non-synonymous genetic variants	127:157	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity	127:242	Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified.					
35841754	2	53	theme	aglycon	331:337	arg1	naringenin					339:348	their aglycon naringenin	325:348	their aglycon naringenin	325:348	Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2.					
35841754	0	54	theme	naringenin	63:72	arg1	properties					29:38	the inhibitory properties	14:38	the inhibitory properties of the fruit component naringenin	14:72	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	4	55	theme	naringenin	626:635	arg1	effects					615:621	the inhibitory effects	600:621	the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	600:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	9	56	theme	Ala187Thr	1434:1442	arg1	variant					1444:1450	the Ala187Thr variant	1430:1450	the Ala187Thr variant	1430:1450	These results suggest that the Ala187Thr variant is less vulnerable to inhibition by naringenin and its glycosides.					
35841754	9	56	theme	Ala187Thr	1434:1442	arg1	vulnerable					1460:1469	vulnerable	1460:1469	vulnerable	1460:1469	These results suggest that the Ala187Thr variant is less vulnerable to inhibition by naringenin and its glycosides.					
35841754	6	57	theme	naringin	1039:1046	arg1	Ki					1032:1033	Ki	1032:1033	Ki	1032:1033	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	6	57	theme	naringin	1039:1046	arg1	constants					1021:1029	the inhibition constants	1006:1029	the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant	1006:1095	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	4	58	theme	inhibitory	604:613	arg1	effects					615:621	the inhibitory effects	600:621	the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser)	600:825	This study aimed to investigate the inhibitory effects of naringenin, its monosaccharide glycoside prunin, and its disaccharide glycosides naringin and narirutin on fexofenadine (FEX) uptake by OATP1A2 variants (Ile13Thr, Asn128Tyr, Ala187Thr, and Thr668Ser).					
35841754	0	59	theme	fruit	47:51	arg1	naringenin					63:72	the fruit component naringenin	43:72	the fruit component naringenin	43:72	Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.					
35841754	6	60	theme	prunin	1064:1069	arg1	Ki					1032:1033	Ki	1032:1033	Ki	1032:1033	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	6	60	theme	prunin	1064:1069	arg1	constants					1021:1029	the inhibition constants	1006:1029	the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant	1006:1095	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
35841754	7	61	theme	OATP1A2	1212:1218	arg1	variants					1220:1227	the OATP1A2 variants	1208:1227	the OATP1A2 variants	1208:1227	Naringenin inhibited all of the OATP1A2 variants, except Ala187Thr, concentration-dependently.					
35841754	3	62	theme	number	513:518	arg1	influence					461:469	the influence	457:469	the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency	457:565	However, their inhibitory effects on OATP1A2 variants have not been investigated, nor has the influence of their molecular structure, such as the number of sugar moieties, on their inhibitory potency.					
35841754	6	63	theme	wild	995:998	arg1	type					1000:1003	the wild type	991:1003	the wild type	991:1003	Compared with those for the wild type, the inhibition constants (Ki) of naringin, narirutin, and prunin for the Ala187Thr variant were significantly increased by 3.36-fold, 7.55-fold, and 10.6-fold, respectively.					
36155077	0	0	theme	various	81:87	arg1	modes					89:93	various modes	81:93	various modes of high performance liquid chromatography	81:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	3	1	theme	resolution	703:712	arg1	separations					714:724	high resolution separations	698:724	high resolution separations for 1-NA- and 2-AA-sugar derivatives	698:761	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	2	theme	dodecyl	818:824	arg1	DTAB					853:856	DTAB	853:856	DTAB	853:856	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	2	theme	dodecyl	818:824	arg1	bromide					844:850	the ion-pairing agent dodecyl trimethylammonium bromide	796:850	the ion-pairing agent dodecyl trimethylammonium bromide (DTAB)	796:857	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	1	3	theme	oligosaccharides	336:351	arg1	separations					289:299	the separations	285:299	the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	285:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	2	4	theme	sugar	584:588	arg1	derivatives					590:600	the sugar derivatives	580:600	the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes	580:677	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	1	5	with	mono-	326:330	arg1	1-naphthylamine					394:408	1-naphthylamine	394:408	1-naphthylamine (1-NA)	394:415	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	5	with	mono-	326:330	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	5	with	mono-	326:330	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	5	with	mono-	326:330	arg1	2-aminoanthracene					418:434	2-aminoanthracene	418:434	2-aminoanthracene (2-AA)	418:441	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	3	6	theme	trimethylammonium	826:842	arg1	DTAB					853:856	DTAB	853:856	DTAB	853:856	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	6	theme	trimethylammonium	826:842	arg1	bromide					844:850	the ion-pairing agent dodecyl trimethylammonium bromide	796:850	the ion-pairing agent dodecyl trimethylammonium bromide (DTAB)	796:857	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	2	7	theme	chromatographic	657:671	arg1	modes					673:677	chromatographic modes	657:677	chromatographic modes	657:677	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	3	8	from	RPC	773:775	arg1	presence					784:791	the presence	780:791	the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase	780:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	9	theme	derivatives	967:977	arg1	separation					941:950	the separation	937:950	the separation of ANDSA-sugar derivatives	937:977	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	10	theme	ion-pairing	800:810	arg1	DTAB					853:856	DTAB	853:856	DTAB	853:856	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	10	theme	ion-pairing	800:810	arg1	bromide					844:850	the ion-pairing agent dodecyl trimethylammonium bromide	796:850	the ion-pairing agent dodecyl trimethylammonium bromide (DTAB)	796:857	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	0	11	from	di-	53:55	arg1	modes					89:93	various modes	81:93	various modes of high performance liquid chromatography	81:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	4	12	theme	ionic	1164:1168	arg1	species					1183:1189	ionic or ionizable species	1164:1189	ionic or ionizable species	1164:1189	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	5	13	from	analysis	1256:1263	arg1	characteristics					1204:1218	the characteristics	1200:1218	the characteristics of each chromatographic mode in the analysis of derivatized sugars	1200:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	3	14	theme	more	893:896	arg1	resolution					898:907	far more resolution	889:907	far more resolution	889:907	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	15	attach	presence	784:791	arg2	bromide					844:850	the ion-pairing agent dodecyl trimethylammonium bromide	796:850	the ion-pairing agent dodecyl trimethylammonium bromide (DTAB)	796:857	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	15	attach	presence	784:791	arg2	DTAB					853:856	DTAB	853:856	DTAB	853:856	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	15	attach	presence	784:791	arg1	phase					873:877	the mobile phase	862:877	the mobile phase	862:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	0	16	theme	performance	103:113	arg1	chromatography					122:135	high performance liquid chromatography	98:135	high performance liquid chromatography	98:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	1	17	theme	following	362:370	arg1	1-naphthylamine					394:408	1-naphthylamine	394:408	1-naphthylamine (1-NA)	394:415	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	17	theme	following	362:370	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	17	theme	following	362:370	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	17	theme	following	362:370	arg1	2-aminoanthracene					418:434	2-aminoanthracene	418:434	2-aminoanthracene (2-AA)	418:441	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	5	18	theme	mode	1244:1247	arg1	characteristics					1204:1218	the characteristics	1200:1218	the characteristics of each chromatographic mode in the analysis of derivatized sugars	1200:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	5	19	from	mode	1244:1247	arg1	analysis					1256:1263	the analysis	1252:1263	the analysis of derivatized sugars	1252:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	5	20	theme	sugars	1280:1285	arg1	analysis					1256:1263	the analysis	1252:1263	the analysis of derivatized sugars	1252:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	1	21	theme	reversed-phase	172:185	arg1	RPC					203:205	RPC	203:205	RPC	203:205	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	21	theme	reversed-phase	172:185	arg1	chromatography					187:200	reversed-phase chromatography	172:200	reversed-phase chromatography (RPC)	172:206	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	0	22	theme	high	98:101	arg1	chromatography					122:135	high performance liquid chromatography	98:135	high performance liquid chromatography	98:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	0	23	from	mono-	46:50	arg1	modes					89:93	various modes	81:93	various modes of high performance liquid chromatography	81:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	1	24	theme	tagging	378:384	arg1	1-naphthylamine					394:408	1-naphthylamine	394:408	1-naphthylamine (1-NA)	394:415	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	24	theme	tagging	378:384	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	24	theme	tagging	378:384	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	24	theme	tagging	378:384	arg1	2-aminoanthracene					418:434	2-aminoanthracene	418:434	2-aminoanthracene (2-AA)	418:441	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	2	25	theme	elution	610:616	arg1	patterns					618:625	elution patterns	610:625	elution patterns in the three, just mentioned, chromatographic modes	610:677	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	1	26	theme	3-amino-2,7-naphthalenedisulfonic	448:480	arg1	ANDSA					488:492	ANDSA	488:492	ANDSA	488:492	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	26	theme	3-amino-2,7-naphthalenedisulfonic	448:480	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	26	theme	3-amino-2,7-naphthalenedisulfonic	448:480	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	3	27	from	presence	784:791	arg1	phase					873:877	the mobile phase	862:877	the mobile phase	862:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	0	28	theme	Retention	0:8	arg1	behaviors					10:18	Retention behaviors	0:18	Retention behaviors of pre-column	0:32	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	3	29	theme	2-AA-sugar	740:749	arg1	derivatives					751:761	1-NA- and 2-AA-sugar derivatives	730:761	1-NA- and 2-AA-sugar derivatives	730:761	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	4	30	theme	ion-exchange	1111:1122	arg1	column					1124:1129	an ion-exchange column	1108:1129	an ion-exchange column	1108:1129	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	0	31	theme	pre-column	23:32	arg1	behaviors					10:18	Retention behaviors	0:18	Retention behaviors of pre-column	0:32	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	0	32	theme	chromatography	122:135	arg1	modes					89:93	various modes	81:93	various modes of high performance liquid chromatography	81:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	2	33	theme	mentioned	646:654	arg1	modes					673:677	chromatographic modes	657:677	chromatographic modes	657:677	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	3	34	theme	agent	812:816	arg1	DTAB					853:856	DTAB	853:856	DTAB	853:856	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	3	34	theme	agent	812:816	arg1	bromide					844:850	the ion-pairing agent dodecyl trimethylammonium bromide	796:850	the ion-pairing agent dodecyl trimethylammonium bromide (DTAB)	796:857	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	4	35	theme	most	1084:1087	arg1	cases					1089:1093	most cases	1084:1093	most cases	1084:1093	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	4	36	theme	octadecyl	1019:1027	arg1	column					1029:1034	an octadecyl column	1016:1034	an octadecyl column operating in ion-pair RPC mode	1016:1065	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	3	37	theme	1-NA-	730:734	arg1	derivatives					751:761	1-NA- and 2-AA-sugar derivatives	730:761	1-NA- and 2-AA-sugar derivatives	730:761	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	0	38	theme	liquid	115:120	arg1	chromatography					122:135	high performance liquid chromatography	98:135	high performance liquid chromatography	98:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	5	39	theme	various	1307:1313	arg1	compositions					1328:1339	various mobile phase compositions	1307:1339	various mobile phase compositions	1307:1339	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	4	40	theme	RPC	1058:1060	arg1	mode					1062:1065	ion-pair RPC mode	1049:1065	ion-pair RPC mode	1049:1065	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	5	41	theme	mobile	1315:1320	arg1	compositions					1328:1339	various mobile phase compositions	1307:1339	various mobile phase compositions	1307:1339	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	1	42	theme	ion-pair	209:216	arg1	RPC					218:220	ion-pair RPC	209:220	ion-pair RPC	209:220	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	0	43	from	oligosaccharides	61:76	arg1	modes					89:93	various modes	81:93	various modes of high performance liquid chromatography	81:135	Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography.					
36155077	1	44	dep	agents	386:391	arg1	1-naphthylamine					394:408	1-naphthylamine	394:408	1-naphthylamine (1-NA)	394:415	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	2-AA					437:440	2-AA	437:440	2-AA	437:440	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	ANDSA					488:492	ANDSA	488:492	ANDSA	488:492	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	1-NA					411:414	1-NA	411:414	1-NA	411:414	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	2-aminoanthracene					418:434	2-aminoanthracene	418:434	2-aminoanthracene (2-AA)	418:441	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	44	dep	agents	386:391	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	2	45	from	patterns	618:625	arg1	modes					673:677	chromatographic modes	657:677	chromatographic modes	657:677	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	3	46	theme	high	698:701	arg1	separations					714:724	high resolution separations	698:724	high resolution separations for 1-NA- and 2-AA-sugar derivatives	698:761	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	1	47	theme	precolumn	304:312	arg1	mono-					326:330	precolumn derivatized mono-	304:330	precolumn derivatized mono-	304:330	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	2	48	theme	tagging	556:562	arg1	agents					564:569	the three tagging agents	546:569	the three tagging agents	546:569	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	2	49	from	differences	503:513	arg1	polarity					536:543	polarity	536:543	polarity	536:543	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	2	49	from	differences	503:513	arg1	charges					524:530	their charges	518:530	their charges	518:530	Due to differences in their charges and polarity, the three tagging agents imparted the sugar derivatives varying elution patterns in the three, just mentioned, chromatographic modes.					
36155077	4	50	theme	species	1183:1189	arg1	separations					1149:1159	bioanalytical separations	1135:1159	bioanalytical separations of ionic or ionizable species	1135:1189	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	1	51	theme	derivatized	314:324	arg1	mono-					326:330	precolumn derivatized mono-	304:330	precolumn derivatized mono-	304:330	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	5	52	from	characteristics	1204:1218	arg1	analysis					1256:1263	the analysis	1252:1263	the analysis of derivatized sugars	1252:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	5	53	theme	phase	1322:1326	arg1	compositions					1328:1339	various mobile phase compositions	1307:1339	various mobile phase compositions	1307:1339	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	4	54	theme	ionizable	1173:1181	arg1	species					1183:1189	ionic or ionizable species	1164:1189	ionic or ionizable species	1164:1189	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	5	55	theme	derivatized	1268:1278	arg1	sugars					1280:1285	derivatized sugars	1268:1285	derivatized sugars	1268:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36155077	3	56	theme	ion-pair	764:771	arg1	RPC					773:775	ion-pair RPC	764:775	ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase	764:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	4	57	theme	bioanalytical	1135:1147	arg1	separations					1149:1159	bioanalytical separations	1135:1159	bioanalytical separations of ionic or ionizable species	1135:1189	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	3	58	theme	bromide	844:850	arg1	presence					784:791	the presence	780:791	the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase	780:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	1	59	theme	weak	226:229	arg1	WAX					262:264	WAX	262:264	WAX	262:264	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	59	theme	weak	226:229	arg1	chromatography					246:259	weak anion-exchange chromatography	226:259	weak anion-exchange chromatography (WAX)	226:265	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	4	60	theme	ion-pair	1049:1056	arg1	mode					1062:1065	ion-pair RPC mode	1049:1065	ion-pair RPC mode	1049:1065	This finding portrays the fact that an octadecyl column operating in ion-pair RPC mode can eliminate in most cases the need for an ion-exchange column for bioanalytical separations of ionic or ionizable species.					
36155077	3	61	theme	mobile	866:871	arg1	phase					873:877	the mobile phase	862:877	the mobile phase	862:877	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	1	62	theme	LC-based	144:151	arg1	methods					153:159	Three LC-based methods	138:159	Three LC-based methods	138:159	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	62	theme	LC-based	144:151	arg1	chromatography					246:259	weak anion-exchange chromatography	226:259	weak anion-exchange chromatography (WAX)	226:265	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	62	theme	LC-based	144:151	arg1	chromatography					187:200	reversed-phase chromatography	172:200	reversed-phase chromatography (RPC)	172:206	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	62	theme	LC-based	144:151	arg1	RPC					218:220	ion-pair RPC	209:220	ion-pair RPC	209:220	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	63	theme	anion-exchange	231:244	arg1	WAX					262:264	WAX	262:264	WAX	262:264	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	63	theme	anion-exchange	231:244	arg1	chromatography					246:259	weak anion-exchange chromatography	226:259	weak anion-exchange chromatography (WAX)	226:265	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	64	theme	mono-	326:330	arg1	separations					289:299	the separations	285:299	the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	285:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	3	65	theme	ANDSA-sugar	955:965	arg1	derivatives					967:977	ANDSA-sugar derivatives	955:977	ANDSA-sugar derivatives	955:977	While RPC yielded high resolution separations for 1-NA- and 2-AA-sugar derivatives, ion-pair RPC in the presence of the ion-pairing agent dodecyl trimethylammonium bromide (DTAB) in the mobile phase exhibited far more resolution and selectivity than WAX in the separation of ANDSA-sugar derivatives.					
36155077	1	66	with	oligosaccharides	336:351	arg1	1-naphthylamine					394:408	1-naphthylamine	394:408	1-naphthylamine (1-NA)	394:415	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	66	with	oligosaccharides	336:351	arg1	agents					386:391	the following three tagging agents	358:391	the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	358:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	66	with	oligosaccharides	336:351	arg1	acid					482:485	3-amino-2,7-naphthalenedisulfonic acid	448:485	3-amino-2,7-naphthalenedisulfonic acid (ANDSA)	448:493	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	1	66	with	oligosaccharides	336:351	arg1	2-aminoanthracene					418:434	2-aminoanthracene	418:434	2-aminoanthracene (2-AA)	418:441	Three LC-based methods, including reversed-phase chromatography (RPC), ion-pair RPC and weak anion-exchange chromatography (WAX), were examined in the separations of precolumn derivatized mono- and oligosaccharides with the following three tagging agents: 1-naphthylamine (1-NA), 2-aminoanthracene (2-AA), and 3-amino-2,7-naphthalenedisulfonic acid (ANDSA).					
36155077	5	67	theme	chromatographic	1228:1242	arg1	mode					1244:1247	each chromatographic mode	1223:1247	each chromatographic mode in the analysis of derivatized sugars	1223:1285	Lastly, the characteristics of each chromatographic mode in the analysis of derivatized sugars are described using various mobile phase compositions.					
36220010	6	0	theme	adhesion	1148:1155	arg1	aspects					1132:1138	the aspects	1128:1138	the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression	1128:1216	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	15	1	theme	hydrogel	1938:1945	arg1	scaffolds					1952:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	15	2	theme	alkaline	2008:2015	arg1	phosphatase					2017:2027	alkaline phosphatase	2008:2027	alkaline phosphatase activity	2008:2036	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	10	3	theme	experiment<i>in	1468:1482	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	3	theme	experiment<i>in	1468:1482	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	15	4	theme	%	1925:1925	arg1	scaffolds					1952:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	1	5	theme	bone	281:284	arg1	growth					286:291	bone growth	281:291	bone growth	281:291	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	10	6	theme	experiment<i>in	1516:1530	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	6	theme	experiment<i>in	1516:1530	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	4	7	theme	antibacterial	888:900	arg1	properties					902:911	antibacterial properties	888:911	antibacterial properties	888:911	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	13	8	theme	antibacterial	1850:1862	arg1	effect					1864:1869	the antibacterial effect	1846:1869	the antibacterial effect	1846:1869	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	13	8	theme	antibacterial	1850:1862	arg1	best					1879:1882	best	1879:1882	best	1879:1882	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	10	9	theme	vancomycin	1497:1506	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	9	theme	vancomycin	1497:1506	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	2	10	theme	main	318:321	arg1	loosening					369:377	aseptic loosening	361:377	aseptic loosening	361:377	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	2	10	theme	main	318:321	arg1	causes					323:328	The two main causes	310:328	The two main causes of implant surgery failure	310:355	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	5	11	theme	antibacterial	918:930	arg1	properties					932:941	The antibacterial properties	914:941	The antibacterial properties of the complex	914:956	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	11	12	theme	release	1653:1659	arg1	times					1661:1665	longer release times	1646:1665	longer release times	1646:1665	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	17	13	theme	3D	2338:2339	arg1	printing					2341:2348	future 3D printing	2331:2348	future 3D printing	2331:2348	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	2	14	theme	bacterial-induced	383:399	arg1	infections					420:429	bacterial-induced implant-associated infections	383:429	bacterial-induced implant-associated infections	383:429	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	15	15	theme	cell	1978:1981	arg1	proliferation					1983:1995	cell proliferation	1978:1995	cell proliferation	1978:1995	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	12	16	theme	<i>in	1680:1684	arg1	vitro</i>studies					1686:1701	<i>in vitro</i>studies	1680:1701	<i>in vitro</i>studies	1680:1701	In addition,<i>in vitro</i>studies found that the TTNZ scaffolds loaded with 5 wt.					
36220010	15	17	theme	free	2114:2117	arg1	bacteria					2119:2126	free bacteria	2114:2126	free bacteria	2114:2126	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	17	18	theme	release	2279:2285	arg1	rate					2287:2290	the local release rate	2269:2290	the local release rate of vancomycin	2269:2304	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	17	19	theme	alloy	2362:2366	arg1	stents					2368:2373	titanium alloy stents	2353:2373	titanium alloy stents	2353:2373	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	5	20	theme	inhibition	991:1000	arg1	test					1002:1005	inhibition test	991:1005	inhibition test	991:1005	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	6	21	theme	composite	1068:1076	arg1	system					1078:1083	the composite system	1064:1083	the composite system	1064:1083	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	11	22	theme	drug-loaded	1584:1594	arg1	hydrogels					1596:1604	the drug-loaded hydrogels	1580:1604	the drug-loaded hydrogels	1580:1604	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	0	23	theme	porous	76:81	arg1	scaffolds					83:91	3D-printed porous scaffolds	65:91	3D-printed porous scaffolds	65:91	<i>In vitro</i>application of drug-loaded hydrogel combined with 3D-printed porous scaffolds.					
36220010	9	24	theme	acid	1334:1337	arg1	hydrogel					1339:1346	chitosan-hyaluronic acid hydrogel	1314:1346	chitosan-hyaluronic acid hydrogel	1314:1346	% vancomycin did not affect the structure of chitosan-hyaluronic acid hydrogel.					
36220010	17	25	theme	vancomycin	2295:2304	arg1	rate					2287:2290	the local release rate	2269:2290	the local release rate of vancomycin	2269:2304	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	15	26	theme	gene	2064:2067	arg1	ex-pression					2069:2079	osteogenesis-related gene ex-pression	2043:2079	osteogenesis-related gene ex-pression	2043:2079	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	15	27	from	effect	2104:2109	arg1	bacteria					2119:2126	free bacteria	2114:2126	free bacteria	2114:2126	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	5	28	theme	complex	950:956	arg1	properties					932:941	The antibacterial properties	914:941	The antibacterial properties of the complex	914:956	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	13	29	theme	osteogenesis-related	1805:1824	arg1	genes					1826:1830	osteogenesis-related genes	1805:1830	osteogenesis-related genes	1805:1830	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	1	30	theme	titanium	130:137	arg1	scaffolds					145:153	three-dimensional titanium alloy scaffolds	112:153	three-dimensional titanium alloy scaffolds	112:153	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	15	31	theme	TTNZ	2155:2158	arg1	scaffolds					2160:2168	TTNZ scaffolds	2155:2168	TTNZ scaffolds loaded with 5 wt	2155:2185	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	17	32	theme	new	2318:2320	arg1	idea					2322:2325	a new idea	2316:2325	a new idea for future 3D printing of titanium alloy stents	2316:2373	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	13	33	theme	certain	1769:1775	arg1	effect					1777:1782	a certain effect	1767:1782	a certain effect	1767:1782	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	4	34	theme	3D-printed	793:802	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	1	35	theme	Titanium	94:101	arg1	mesh					103:106	Titanium mesh	94:106	Titanium mesh	94:106	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	6	36	from	effects	1053:1059	arg1	osseointegration					1088:1103	osseointegration	1088:1103	osseointegration	1088:1103	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	2	37	theme	implant-associated	401:418	arg1	infections					420:429	bacterial-induced implant-associated infections	383:429	bacterial-induced implant-associated infections	383:429	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	0	38	theme	<i>In	0:4	arg1	vitro</i>application					6:25	<i>In vitro</i>application	0:25	<i>In vitro</i>application of drug-loaded hydrogel	0:49	<i>In vitro</i>application of drug-loaded hydrogel combined with 3D-printed porous scaffolds.					
36220010	13	39	theme	%	1750:1750	arg1	vancomycin					1752:1761	% vancomycin	1750:1761	% vancomycin	1750:1761	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	4	40	theme	vancomycin-loaded	757:773	arg1	hydrogel					775:782	the vancomycin-loaded hydrogel	753:782	the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties	753:911	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	5	41	theme	test	1002:1005	arg1	zone					983:986	the zone	979:986	the zone of inhibition test and the adhesion/free antibacterial test	979:1046	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	3	42	theme	bone	440:443	arg1	implants					452:459	bone defect implants	440:459	bone defect implants effective for a long time	440:485	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	11	43	theme	porous	1562:1567	arg1	scaffolds					1569:1577	porous scaffolds	1562:1577	porous scaffolds	1562:1577	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	3	44	theme	long	477:480	arg1	time					482:485	a long time	475:485	a long time	475:485	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	0	45	theme	hydrogel	42:49	arg1	vitro</i>application					6:25	<i>In vitro</i>application	0:25	<i>In vitro</i>application of drug-loaded hydrogel	0:49	<i>In vitro</i>application of drug-loaded hydrogel combined with 3D-printed porous scaffolds.					
36220010	4	46	dep	alloys	664:669	arg1	basis					608:612	basis	608:612	basis	608:612	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	4	46	dep	alloys	664:669	arg1	the					604:606	the	604:606	the	604:606	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	4	47	theme	3D-printed	857:866	arg1	scaffolds					873:881	3D-printed TTNZ scaffolds	857:881	3D-printed TTNZ scaffolds	857:881	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	2	48	theme	failure	349:355	arg1	loosening					369:377	aseptic loosening	361:377	aseptic loosening	361:377	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	2	48	theme	failure	349:355	arg1	causes					323:328	The two main causes	310:328	The two main causes of implant surgery failure	310:355	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	13	49	from	expression	1791:1800	arg1	cells					1835:1839	cells	1835:1839	cells	1835:1839	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	6	50	theme	osteogenesis-related	1181:1200	arg1	expression					1207:1216	osteogenesis-related gene expression	1181:1216	osteogenesis-related gene expression	1181:1216	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	4	51	theme	porous	817:822	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	2	52	theme	implant	333:339	arg1	failure					349:355	implant surgery failure	333:355	implant surgery failure	333:355	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	6	53	theme	proliferation	1163:1175	arg1	aspects					1132:1138	the aspects	1128:1138	the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression	1128:1216	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	15	54	theme	TTNZ	1947:1950	arg1	scaffolds					1952:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	4	55	theme	alloy	833:837	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	1	56	theme	specific	242:249	arg1	environment					251:261	a specific environment	240:261	a specific environment	240:261	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	4	57	theme	Ti-10Ta-2Nb-2Zr	641:655	arg1	alloys					664:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys	617:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage	617:720	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	15	58	theme	vancomycin	1927:1936	arg1	scaffolds					1952:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds	1925:1960	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	16	59	dep	vancomycin	2189:2198	arg1	%					2187:2187	%	2187:2187	%	2187:2187	% vancomycin.					
36220010	10	60	theme	electron	1407:1414	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	60	theme	electron	1407:1414	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	60	theme	electron	1407:1414	arg1	infrared					1446:1453	Fourier-transform infrared	1428:1453	Fourier-transform infrared	1428:1453	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	2	61	theme	aseptic	361:367	arg1	loosening					369:377	aseptic loosening	361:377	aseptic loosening	361:377	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	2	61	theme	aseptic	361:367	arg1	causes					323:328	The two main causes	310:328	The two main causes of implant surgery failure	310:355	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	6	62	theme	cell	1143:1146	arg1	adhesion					1148:1155	cell adhesion	1143:1155	cell adhesion	1143:1155	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	10	63	theme	degradation	1456:1466	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	63	theme	degradation	1456:1466	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	3	64	theme	osseointegration	553:568	arg1	functions					540:548	the two functions	532:548	the two functions of osseointegration and anti-infection	532:587	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	15	65	theme	osteogenesis-related	2043:2062	arg1	ex-pression					2069:2079	osteogenesis-related gene ex-pression	2043:2079	osteogenesis-related gene ex-pression	2043:2079	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	12	66	dep	scaffolds	1723:1731	arg1	loaded					1733:1738	loaded	1733:1738	scaffolds loaded with 5 wt	1723:1748	In addition,<i>in vitro</i>studies found that the TTNZ scaffolds loaded with 5 wt.					
36220010	11	67	theme	longer	1646:1651	arg1	times					1661:1665	longer release times	1646:1665	longer release times	1646:1665	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	1	68	theme	oral	185:188	arg1	defects					213:219	oral and maxillofacial bone defects	185:219	oral and maxillofacial bone defects	185:219	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	4	69	theme	TTNZ	868:871	arg1	scaffolds					873:881	3D-printed TTNZ scaffolds	857:881	3D-printed TTNZ scaffolds	857:881	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	13	70	contain	had	1763:1765	arg1	vancomycin					1752:1761	% vancomycin	1750:1761	% vancomycin	1750:1761	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	13	70	contain	had	1763:1765	arg2	effect					1777:1782	a certain effect	1767:1782	a certain effect	1767:1782	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	10	71	theme	release	1508:1514	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	71	theme	release	1508:1514	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	1	72	theme	maxillofacial	194:206	arg1	defects					213:219	oral and maxillofacial bone defects	185:219	oral and maxillofacial bone defects	185:219	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	4	73	theme	research	688:695	arg1	group					697:701	the research group	684:701	the research group	684:701	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	9	74	theme	%	1269:1269	arg1	vancomycin					1271:1280	% vancomycin	1269:1280	% vancomycin	1269:1280	% vancomycin did not affect the structure of chitosan-hyaluronic acid hydrogel.					
36220010	3	75	theme	anti-infection	574:587	arg1	functions					540:548	the two functions	532:548	the two functions of osseointegration and anti-infection	532:587	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	17	76	theme	future	2331:2336	arg1	printing					2341:2348	future 3D printing	2331:2348	future 3D printing	2331:2348	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	6	77	theme	expression	1207:1216	arg1	aspects					1132:1138	the aspects	1128:1138	the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression	1128:1216	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	4	78	theme	TTNZ	658:661	arg1	alloys					664:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys	617:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage	617:720	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	4	79	with	hydrogel	775:782	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	1	80	theme	bone	208:211	arg1	defects					213:219	oral and maxillofacial bone defects	185:219	oral and maxillofacial bone defects	185:219	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	1	81	theme	alloy	139:143	arg1	scaffolds					145:153	three-dimensional titanium alloy scaffolds	112:153	three-dimensional titanium alloy scaffolds	112:153	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	17	82	theme	titanium	2353:2360	arg1	stents					2368:2373	titanium alloy stents	2353:2373	titanium alloy stents	2353:2373	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	10	83	theme	vitro</i>and	1484:1495	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	83	theme	vitro</i>and	1484:1495	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	6	84	theme	system	1078:1083	arg1	effects					1053:1059	The effects	1049:1059	The effects of the composite system on osseointegration	1049:1103	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	17	85	theme	stents	2368:2373	arg1	idea					2322:2325	a new idea	2316:2325	a new idea for future 3D printing of titanium alloy stents	2316:2373	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	3	86	theme	ideal	492:496	arg1	scaffold					498:505	the ideal scaffold	488:505	the ideal scaffold	488:505	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	9	87	theme	chitosan-hyaluronic	1314:1332	arg1	hydrogel					1339:1346	chitosan-hyaluronic acid hydrogel	1314:1346	chitosan-hyaluronic acid hydrogel	1314:1346	% vancomycin did not affect the structure of chitosan-hyaluronic acid hydrogel.					
36220010	11	88	theme	drug	1623:1626	arg1	rates					1636:1640	slower drug release rates	1616:1640	slower drug release rates	1616:1640	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	1	89	theme	key	162:164	arg1	role					166:169	a key role	160:169	a key role	160:169	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	11	90	theme	release	1628:1634	arg1	rates					1636:1640	slower drug release rates	1616:1640	slower drug release rates	1616:1640	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	9	91	theme	hydrogel	1339:1346	arg1	structure					1301:1309	the structure	1297:1309	the structure of chitosan-hyaluronic acid hydrogel	1297:1346	% vancomycin did not affect the structure of chitosan-hyaluronic acid hydrogel.					
36220010	4	92	theme	early	710:714	arg1	stage					716:720	the early stage	706:720	the early stage	706:720	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	11	93	theme	slower	1616:1621	arg1	rates					1636:1640	slower drug release rates	1616:1640	slower drug release rates	1616:1640	When combined with porous scaffolds, the drug-loaded hydrogels exhibited slower drug release rates and longer release times.					
36220010	13	94	theme	genes	1826:1830	arg1	expression					1791:1800	the expression	1787:1800	the expression of osteogenesis-related genes in cells	1787:1839	% vancomycin had a certain effect on the expression of osteogenesis-related genes in cells, but the antibacterial effect was the best.					
36220010	17	95	theme	two	2249:2251	arg1	advantages					2231:2240	the advantages	2227:2240	the advantages of the two	2227:2251	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	5	96	theme	adhesion/free	1015:1027	arg1	test					1043:1046	the adhesion/free antibacterial test	1011:1046	the adhesion/free antibacterial test	1011:1046	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	17	97	dep	study	2206:2210	arg1	controlling					2257:2267	controlling	2257:2267	controlling the local release rate of vancomycin	2257:2304	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	17	97	dep	study	2206:2210	arg1	complementing					2213:2225	complementing	2213:2225	complementing the advantages of the two	2213:2251	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	7	98	theme	loading	1243:1249	arg1	wt					1255:1256	that loading 2.5 wt	1238:1256	that loading 2.5 wt	1238:1256	The results showed that loading 2.5 wt.					
36220010	15	99	theme	phosphatase	2017:2027	arg1	activity					2029:2036	alkaline phosphatase activity	2008:2036	alkaline phosphatase activity	2008:2036	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	17	100	theme	local	2273:2277	arg1	rate					2287:2290	the local release rate	2269:2290	the local release rate of vancomycin	2269:2304	This study, complementing the advantages of the two and controlling the local release rate of vancomycin, provides a new idea for future 3D printing of titanium alloy stents for anti-infection.					
36220010	10	101	theme	hydrogels	1371:1379	arg1	properties					1353:1362	The properties	1349:1362	The properties of the hydrogels	1349:1379	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	3	102	theme	effective	461:469	arg1	implants					452:459	bone defect implants	440:459	bone defect implants effective for a long time	440:485	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	0	103	theme	drug-loaded	30:40	arg1	hydrogel					42:49	drug-loaded hydrogel	30:49	drug-loaded hydrogel	30:49	<i>In vitro</i>application of drug-loaded hydrogel combined with 3D-printed porous scaffolds.					
36220010	1	104	theme	three-dimensional	112:128	arg1	scaffolds					145:153	three-dimensional titanium alloy scaffolds	112:153	three-dimensional titanium alloy scaffolds	112:153	Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development.					
36220010	14	105	theme	porous	1889:1894	arg1	scaffolds					1896:1904	The porous scaffolds	1885:1904	The porous scaffolds	1885:1904	The porous scaffolds loaded with 2.5 wt.					
36220010	3	106	theme	defect	445:450	arg1	implants					452:459	bone defect implants	440:459	bone defect implants effective for a long time	440:485	To make bone defect implants effective for a long time, the ideal scaffold should take into account the two functions of osseointegration and anti-infection.					
36220010	10	107	theme	scanning	1398:1405	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	107	theme	scanning	1398:1405	arg1	vitro</i>					1532:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>	1456:1540	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	107	theme	scanning	1398:1405	arg1	infrared					1446:1453	Fourier-transform infrared	1428:1453	Fourier-transform infrared	1428:1453	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	0	108	theme	3D-printed	65:74	arg1	scaffolds					83:91	3D-printed porous scaffolds	65:91	3D-printed porous scaffolds	65:91	<i>In vitro</i>application of drug-loaded hydrogel combined with 3D-printed porous scaffolds.					
36220010	6	109	theme	gene	1202:1205	arg1	expression					1207:1216	osteogenesis-related gene expression	1181:1216	osteogenesis-related gene expression	1181:1216	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	15	110	theme	antibacterial	2090:2102	arg1	good					2139:2142	good	2139:2142	good	2139:2142	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	15	110	theme	antibacterial	2090:2102	arg1	effect					2104:2109	the antibacterial effect	2086:2109	the antibacterial effect on free bacteria	2086:2126	% vancomycin hydrogel TTNZ scaffolds did not inhibit cell proliferation, adhesion, alkaline phosphatase activity, and osteogenesis-related gene ex-pression, but the antibacterial effect on free bacteria was not as good as that of TTNZ scaffolds loaded with 5 wt.					
36220010	2	111	theme	surgery	341:347	arg1	failure					349:355	implant surgery failure	333:355	implant surgery failure	333:355	The two main causes of implant surgery failure are aseptic loosening and bacterial-induced implant-associated infections.					
36220010	5	112	theme	test	1043:1046	arg1	zone					983:986	the zone	979:986	the zone of inhibition test and the adhesion/free antibacterial test	979:1046	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	4	113	theme	low-elastic-modulus	621:639	arg1	alloys					664:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys	617:669	the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage	617:720	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	5	114	theme	antibacterial	1029:1041	arg1	test					1043:1046	the adhesion/free antibacterial test	1011:1046	the adhesion/free antibacterial test	1011:1046	The antibacterial properties of the complex were investigated by the zone of inhibition test and the adhesion/free antibacterial test.					
36220010	4	115	theme	through-hole	804:815	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36220010	10	116	theme	Fourier-transform	1428:1444	arg1	microscopy					1416:1425	scanning electron microscopy	1398:1425	scanning electron microscopy	1398:1425	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	10	116	theme	Fourier-transform	1428:1444	arg1	infrared					1446:1453	Fourier-transform infrared	1428:1453	Fourier-transform infrared	1428:1453	The properties of the hydrogels were examined by scanning electron microscopy, Fourier-transform infrared, degradation experiment<i>in vitro</i>and vancomycin release experiment<i>in vitro</i>.					
36220010	6	117	theme	cell	1158:1161	arg1	proliferation					1163:1175	cell proliferation	1158:1175	cell proliferation	1158:1175	The effects of the composite system on osseointegration were investigated from the aspects of cell adhesion, cell proliferation and osteogenesis-related gene expression.					
36220010	4	118	theme	titanium	824:831	arg1	scaffold					839:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	the 3D-printed through-hole porous titanium alloy scaffold	789:846	Therefore, on the basis of the low-elastic-modulus Ti-10Ta-2Nb-2Zr (TTNZ) alloys developed by the research group in the early stage, this study intends to combine the vancomycin-loaded hydrogel with the 3D-printed through-hole porous titanium alloy scaffold to endow 3D-printed TTNZ scaffolds with antibacterial properties.					
36382542	6	0	theme	mixing	962:967	arg1	time					969:972	mixing time	962:972	mixing time of excipients both hardness	962:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	3	1	theme	excipients	514:523	arg1	blend					505:509	the physical blend	492:509	the physical blend of excipients	492:523	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	4	2	theme	average	610:616	arg1	less					663:666	less	663:666	less	663:666	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	4	2	theme	average	610:616	arg1	size					627:630	The average particle size	606:630	The average particle size of co-processed excipients	606:657	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	0	3	theme	B2	79:80	arg1	spotlight					90:98	US10071059 B2: patent spotlight	68:98	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.	0:99	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	4	4	theme	lactose-coated	716:729	arg1	particles					731:739	large individual lactose-coated particles	699:739	large individual lactose-coated particles	699:739	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	0	5	theme	patent	83:88	arg1	spotlight					90:98	US10071059 B2: patent spotlight	68:98	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.	0:99	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	4	6	from	shape	809:813	arg1	irregular					796:804	irregular	796:804	irregular	796:804	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	4	7	theme	blend	763:767	arg1	particles					769:777	the physical blend particles	750:777	the physical blend particles	750:777	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	3	8	theme	scanning	547:554	arg1	microscopy					565:574	scanning electron microscopy	547:574	scanning electron microscopy	547:574	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	1	9	theme	particle	169:176	arg1	structure					178:186	the particle structure	165:186	the particle structure of other excipients to overcome the deficiencies of each excipients	165:254	Co-processing involves the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients.					
36382542	4	10	theme	particle	618:625	arg1	less					663:666	less	663:666	less	663:666	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	4	10	theme	particle	618:625	arg1	size					627:630	The average particle size	606:630	The average particle size of co-processed excipients	606:657	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	6	11	with	disintegration	921:934	arg1	increase					950:957	increase	950:957	increase in mixing time of excipients both hardness	950:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	6	11	with	disintegration	921:934	arg1	decreases					1026:1034	disintegration time decreases	1006:1034	disintegration time decreases	1006:1034	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	4	12	from	irregular	796:804	arg1	shape					809:813	shape	809:813	shape	809:813	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	3	13	theme	electron	556:563	arg1	microscopy					565:574	scanning electron microscopy	547:574	scanning electron microscopy	547:574	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	3	14	theme	excipients	457:466	arg1	blend					468:472	The co-processed excipients blend	440:472	The co-processed excipients blend	440:472	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	0	15	theme	tablet	13:18	arg1	composition					30:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	0	15	theme	tablet	13:18	arg1	use					63:65	its preparation and use	43:65	its preparation and use	43:65	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	2	16	theme	mannitol	338:345	arg1	co-processing					290:302	co-processing	290:302	co-processing	290:302	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	4	17	theme	individual	705:714	arg1	particles					731:739	large individual lactose-coated particles	699:739	large individual lactose-coated particles	699:739	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	0	18	theme	Co-processed	0:11	arg1	composition					30:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	0	18	theme	Co-processed	0:11	arg1	use					63:65	its preparation and use	43:65	its preparation and use	43:65	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	1	19	theme	other	191:195	arg1	excipients					197:206	other excipients	191:206	other excipients	191:206	Co-processing involves the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients.					
36382542	5	20	theme	co-processed	858:869	arg1	excipients					871:880	co-processed excipients	858:880	co-processed excipients	858:880	Tablets made from both physical blend and co-processed excipients were compared.					
36382542	6	21	theme	time	1021:1024	arg1	decreases					1026:1034	disintegration time decreases	1006:1034	disintegration time decreases	1006:1034	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	2	22	theme	cellulose	324:332	arg1	co-processing					290:302	co-processing	290:302	co-processing	290:302	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	1	23	theme	excipients	197:206	arg1	structure					178:186	the particle structure	165:186	the particle structure of other excipients to overcome the deficiencies of each excipients	165:254	Co-processing involves the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients.					
36382542	0	24	theme	excipient	20:28	arg1	composition					30:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	0	24	theme	excipient	20:28	arg1	use					63:65	its preparation and use	43:65	its preparation and use	43:65	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	6	25	theme	disintegration	1006:1019	arg1	decreases					1026:1034	disintegration time decreases	1006:1034	disintegration time decreases	1006:1034	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	6	26	dep	excipients	977:986	arg1	both					988:991	both	988:991	both	988:991	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	2	27	theme	microcrystalline	307:322	arg1	cellulose					324:332	microcrystalline cellulose	307:332	microcrystalline cellulose	307:332	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	2	28	theme	tablet	420:425	arg1	composition					427:437	tablet composition	420:437	tablet composition	420:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	6	29	from	decreases	1026:1034	arg1	time					969:972	mixing time	962:972	mixing time of excipients both hardness	962:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	4	30	theme	large	699:703	arg1	particles					731:739	large individual lactose-coated particles	699:739	large individual lactose-coated particles	699:739	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	3	31	theme	co-processed	444:455	arg1	blend					468:472	The co-processed excipients blend	440:472	The co-processed excipients blend	440:472	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	2	32	with	agglomeration	361:373	arg1	aim					383:385	an aim to limit the use of lubricant in tablet composition	380:437	an aim to limit the use of lubricant in tablet composition	380:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	2	33	theme	lubricant	407:415	arg1	use					400:402	the use	396:402	the use of lubricant in tablet composition	396:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	5	34	theme	physical	839:846	arg1	blend					848:852	physical blend	839:852	physical blend	839:852	Tablets made from both physical blend and co-processed excipients were compared.					
36382542	4	35	theme	physical	754:761	arg1	particles					769:777	the physical blend particles	750:777	the physical blend particles	750:777	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	0	36	theme	preparation and	47:61	arg1	composition					30:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition	0:40	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	0	36	theme	preparation and	47:61	arg1	use					63:65	its preparation and use	43:65	its preparation and use	43:65	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	6	37	theme	excipients	977:986	arg1	time					969:972	mixing time	962:972	mixing time of excipients both hardness	962:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	2	38	theme	bed	357:359	arg1	agglomeration					361:373	fluid bed agglomeration	351:373	fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition	351:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	6	39	dep	hardness	908:915	arg1	the					904:906	the	904:906	the	904:906	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	6	39	dep	hardness	908:915	arg1	studies					936:942	studies	936:942	studies	936:942	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	0	40	dep	composition	30:40	arg1	spotlight					90:98	US10071059 B2: patent spotlight	68:98	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.	0:99	Co-processed tablet excipient composition, its preparation and use: US10071059 B2: patent spotlight.					
36382542	2	41	from	use	400:402	arg1	composition					427:437	tablet composition	420:437	tablet composition	420:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	2	42	theme	fluid	351:355	arg1	agglomeration					361:373	fluid bed agglomeration	351:373	fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition	351:437	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	4	43	theme	co-processed	635:646	arg1	excipients					648:657	co-processed excipients	635:657	co-processed excipients	635:657	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	2	44	theme	current	261:267	arg1	patent					269:274	The current patent	257:274	The current patent	257:274	The current patent describes the co-processing of microcrystalline cellulose and mannitol via fluid bed agglomeration with an aim to limit the use of lubricant in tablet composition.					
36382542	3	45	theme	physical	496:503	arg1	blend					505:509	the physical blend	492:509	the physical blend of excipients	492:523	The co-processed excipients blend was compared with the physical blend of excipients and characterized for scanning electron microscopy, disintegration and hardness.					
36382542	6	46	with	hardness	908:915	arg1	increase					950:957	increase	950:957	increase in mixing time of excipients both hardness	950:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	6	46	with	hardness	908:915	arg1	decreases					1026:1034	disintegration time decreases	1006:1034	disintegration time decreases	1006:1034	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	6	47	from	increase	950:957	arg1	time					969:972	mixing time	962:972	mixing time of excipients both hardness	962:1000	As per the hardness and disintegration studies, with increase in mixing time of excipients both hardness and disintegration time decreases.					
36382542	4	48	theme	excipients	648:657	arg1	less					663:666	less	663:666	less	663:666	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	4	48	theme	excipients	648:657	arg1	size					627:630	The average particle size	606:630	The average particle size of co-processed excipients	606:657	The average particle size of co-processed excipients was less than 0.55 mm, characterized by large individual lactose-coated particles whereas, the physical blend particles are uncoated and irregular in shape.					
36382542	1	49	theme	excipients	149:158	arg1	incorporation					128:140	the incorporation	124:140	the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients	124:254	Co-processing involves the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients.					
36382542	1	50	theme	excipients	245:254	arg1	deficiencies					224:235	the deficiencies	220:235	the deficiencies of each excipients	220:254	Co-processing involves the incorporation of one excipients into the particle structure of other excipients to overcome the deficiencies of each excipients.					
35429707	2	0	theme	controls	357:364	arg1	precursor					248:256	a carbon precursor	239:256	a carbon precursor	239:256	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	0	theme	controls	357:364	arg1	advantages					283:292	the advantages	279:292	the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product	279:412	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	1	theme	carbon	241:246	arg1	precursor					248:256	a carbon precursor	239:256	a carbon precursor	239:256	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	1	theme	carbon	241:246	arg1	advantages					283:292	the advantages	279:292	the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product	279:412	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	4	2	link	SA-derived	712:721	arg1	carbon					723:728	SA-derived carbon	712:728	SA-derived carbon	712:728	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	6	3	link	SA-derived	1000:1009	arg1	carbon					1018:1023	SA-derived porous carbon	1000:1023	SA-derived porous carbon	1000:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	2	4	theme	clear	297:301	arg1	structure					313:321	clear molecular structure	297:321	clear molecular structure	297:321	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	7	5	theme	application	1264:1274	arg1	prospects					1276:1284	the application prospects	1260:1284	the application prospects of SA-based carbon in ZICs	1260:1311	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	3	6	theme	skeleton	512:519	arg1	mode					535:538	the carbon skeleton cross-linking mode	501:538	the carbon skeleton cross-linking mode	501:538	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	1	7	theme	polysaccharide	184:197	arg1	carbohydrate					199:210	an environment-friendly and low-cost polysaccharide carbohydrate	147:210	an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed	147:233	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	1	7	theme	polysaccharide	184:197	arg1	alginate					130:137	Sodium alginate	123:137	Sodium alginate (SA)	123:142	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	6	8	theme	kg-1	1106:1109	arg1	densities					1050:1058	superior energy densities	1034:1058	superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1	1034:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	2	9	theme	small	324:328	arg1	weight					340:345	small molecular weight	324:345	small molecular weight	324:345	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	5	10	theme	oxygen	873:878	arg1	content					880:886	high oxygen content	868:886	high oxygen content (17.6 at%)	868:897	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	10	theme	oxygen	873:878	arg1	%					896:896	17.6 at%	889:896	17.6 at%	889:896	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	6	11	theme	35.56	1097:1101	arg1	kg-1					1106:1109	78.35 and 35.56 Wh kg-1	1087:1109	kg-1	1106:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	2	12	theme	structure	313:321	arg1	precursor					248:256	a carbon precursor	239:256	a carbon precursor	239:256	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	12	theme	structure	313:321	arg1	advantages					283:292	the advantages	279:292	the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product	279:412	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	4	13	theme	mechanism	699:707	arg1	understanding					664:676	the understanding	660:676	the understanding of the carbonization mechanism of SA-derived carbon	660:728	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	3	14	theme	generation	570:579	arg1	mechanism					581:589	defect generation mechanism	563:589	defect generation mechanism in the process of SA pyrolysis	563:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	6	15	theme	5120 W kg-1	1145:1155	arg1	densities					1124:1132	the power densities	1114:1132	the power densities of 160 and 5120 W kg-1, respectively	1114:1169	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	4	16	theme	SA-derived	712:721	arg1	carbon					723:728	SA-derived carbon	712:728	SA-derived carbon	712:728	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	3	17	theme	SA	609:610	arg1	pyrolysis					612:620	SA pyrolysis	609:620	SA pyrolysis	609:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	5	18	theme	high	903:906	arg1	area					925:928	high specific surface area	903:928	high specific surface area (384.4 m2 g-1)	903:943	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	18	theme	high	903:906	arg1	g-1					940:942	384.4 m2 g-1	931:942	384.4 m2 g-1	931:942	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	7	19	theme	carbon	1298:1303	arg1	prospects					1276:1284	the application prospects	1260:1284	the application prospects of SA-based carbon in ZICs	1260:1311	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	3	20	theme	cross-linking	521:533	arg1	mode					535:538	the carbon skeleton cross-linking mode	501:538	the carbon skeleton cross-linking mode	501:538	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	2	21	theme	sodium	259:264	arg1	alginate					266:273	sodium alginate	259:273	sodium alginate	259:273	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	5	22	theme	at	894:895	arg1	content					880:886	high oxygen content	868:886	high oxygen content (17.6 at%)	868:897	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	22	theme	at	894:895	arg1	%					896:896	17.6 at%	889:896	17.6 at%	889:896	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	6	23	theme	capacitors	960:969	arg1	device					978:983	Zn-ion hybrid capacitors (ZICs) device	946:983	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon	946:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	3	24	from	mode	535:538	arg1	process					598:604	the process	594:604	the process of SA pyrolysis	594:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	0	25	theme	energy	107:112	arg1	storage					114:120	capacitive energy storage	96:120	capacitive energy storage	96:120	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	6	26	theme	Zn-ion	946:951	arg1	capacitors					960:969	Zn-ion hybrid capacitors	946:969	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon	946:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	26	theme	Zn-ion	946:951	arg1	ZICs					972:975	ZICs	972:975	ZICs	972:975	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	4	27	theme	SA-derived	757:766	arg1	carbon					790:795	a stable SA-derived interconnected porous carbon	748:795	a stable SA-derived interconnected porous carbon	748:795	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	7	28	theme	SA-based	1289:1296	arg1	carbon					1298:1303	SA-based carbon	1289:1303	SA-based carbon	1289:1303	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	2	29	theme	composition	387:397	arg1	weight					340:345	small molecular weight	324:345	small molecular weight	324:345	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	29	theme	composition	387:397	arg1	controls					357:364	easy controls	352:364	easy controls	352:364	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	29	theme	composition	387:397	arg1	structure					313:321	clear molecular structure	297:321	clear molecular structure	297:321	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	0	30	theme	Sodium	0:5	arg1	carbon					31:36	Sodium alginate-derived porous carbon	0:36	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.	0:121	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	5	31	from	%	896:896	arg1	at					894:895	17.6 at%	889:896	17.6 at%	889:896	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	32	theme	surface	917:923	arg1	area					925:928	high specific surface area	903:928	high specific surface area (384.4 m2 g-1)	903:943	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	32	theme	surface	917:923	arg1	g-1					940:942	384.4 m2 g-1	931:942	384.4 m2 g-1	931:942	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	6	33	theme	160	1137:1139	arg1	densities					1124:1132	the power densities	1114:1132	the power densities of 160 and 5120 W kg-1, respectively	1114:1169	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	34	dep	densities	1050:1058	arg1	based					1061:1065	based	1061:1065	based on cathode mass	1061:1081	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	0	35	theme	porous	24:29	arg1	carbon					31:36	Sodium alginate-derived porous carbon	0:36	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.	0:121	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	1	36	theme	Sodium	123:128	arg1	SA					140:141	SA	140:141	SA	140:141	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	1	36	theme	Sodium	123:128	arg1	carbohydrate					199:210	an environment-friendly and low-cost polysaccharide carbohydrate	147:210	an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed	147:233	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	1	36	theme	Sodium	123:128	arg1	alginate					130:137	Sodium alginate	123:137	Sodium alginate (SA)	123:142	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	6	37	theme	porous	1011:1016	arg1	carbon					1018:1023	SA-derived porous carbon	1000:1023	SA-derived porous carbon	1000:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	38	theme	SA-derived	1000:1009	arg1	carbon					1018:1023	SA-derived porous carbon	1000:1023	SA-derived porous carbon	1000:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	2	39	theme	easy	352:355	arg1	controls					357:364	easy controls	352:364	easy controls	352:364	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	0	40	theme	carbonization	53:65	arg1	mechanism					67:75	Self-template carbonization mechanism	39:75	Self-template carbonization mechanism	39:75	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	7	41	theme	sodium	1230:1235	arg1	alginate					1237:1244	sodium alginate	1230:1244	sodium alginate	1230:1244	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	4	42	theme	porous	783:788	arg1	carbon					790:795	a stable SA-derived interconnected porous carbon	748:795	a stable SA-derived interconnected porous carbon	748:795	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	2	43	theme	structure	373:381	arg1	weight					340:345	small molecular weight	324:345	small molecular weight	324:345	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	43	theme	structure	373:381	arg1	controls					357:364	easy controls	352:364	easy controls	352:364	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	43	theme	structure	373:381	arg1	structure					313:321	clear molecular structure	297:321	clear molecular structure	297:321	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	44	theme	molecular	303:311	arg1	structure					313:321	clear molecular structure	297:321	clear molecular structure	297:321	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	45	contain	has	275:277	arg1	alginate					266:273	sodium alginate	259:273	sodium alginate	259:273	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	45	contain	has	275:277	arg2	precursor					248:256	a carbon precursor	239:256	a carbon precursor	239:256	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	45	contain	has	275:277	arg2	advantages					283:292	the advantages	279:292	the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product	279:412	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	0	46	link	alginate-derived	7:22	arg1	carbon					31:36	Sodium alginate-derived porous carbon	0:36	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.	0:121	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	6	47	theme	power	1118:1122	arg1	densities					1124:1132	the power densities	1114:1132	the power densities of 160 and 5120 W kg-1, respectively	1114:1169	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	48	theme	78.35	1087:1091	arg1	kg-1					1106:1109	78.35 and 35.56 Wh kg-1	1087:1109	kg-1	1106:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	3	49	theme	carbon	505:510	arg1	mode					535:538	the carbon skeleton cross-linking mode	501:538	the carbon skeleton cross-linking mode	501:538	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	1	50	theme	low-cost	175:182	arg1	carbohydrate					199:210	an environment-friendly and low-cost polysaccharide carbohydrate	147:210	an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed	147:233	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	1	50	theme	low-cost	175:182	arg1	alginate					130:137	Sodium alginate	123:137	Sodium alginate (SA)	123:142	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	2	51	theme	molecular	330:338	arg1	weight					340:345	small molecular weight	324:345	small molecular weight	324:345	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	5	52	theme	high	868:871	arg1	content					880:886	high oxygen content	868:886	high oxygen content (17.6 at%)	868:897	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	52	theme	high	868:871	arg1	%					896:896	17.6 at%	889:896	17.6 at%	889:896	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	6	53	theme	Wh	1103:1104	arg1	kg-1					1106:1109	78.35 and 35.56 Wh kg-1	1087:1109	kg-1	1106:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	0	54	from	application	81:91	arg1	storage					114:120	capacitive energy storage	96:120	capacitive energy storage	96:120	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	3	55	theme	defect	563:568	arg1	mechanism					581:589	defect generation mechanism	563:589	defect generation mechanism in the process of SA pyrolysis	563:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	4	56	theme	carbonization	685:697	arg1	mechanism					699:707	the carbonization mechanism	681:707	the carbonization mechanism of SA-derived carbon	681:728	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	3	57	from	doping	552:557	arg1	process					598:604	the process	594:604	the process of SA pyrolysis	594:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	0	58	theme	capacitive	96:105	arg1	storage					114:120	capacitive energy storage	96:120	capacitive energy storage	96:120	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	1	59	theme	environment-friendly	150:169	arg1	carbohydrate					199:210	an environment-friendly and low-cost polysaccharide carbohydrate	147:210	an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed	147:233	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	1	59	theme	environment-friendly	150:169	arg1	alginate					130:137	Sodium alginate	123:137	Sodium alginate (SA)	123:142	Sodium alginate (SA) is an environment-friendly and low-cost polysaccharide carbohydrate extracted from seaweed.					
35429707	2	60	theme	SA	469:470	arg1	carbonization					472:484	SA carbonization	469:484	SA carbonization	469:484	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	5	61	theme	384.4 m2	931:938	arg1	area					925:928	high specific surface area	903:928	high specific surface area (384.4 m2 g-1)	903:943	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	61	theme	384.4 m2	931:938	arg1	g-1					940:942	384.4 m2 g-1	931:942	384.4 m2 g-1	931:942	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	3	62	theme	heteroatom	541:550	arg1	doping					552:557	heteroatom doping	541:557	heteroatom doping	541:557	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	6	63	theme	hybrid	953:958	arg1	capacitors					960:969	Zn-ion hybrid capacitors	946:969	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon	946:1023	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	63	theme	hybrid	953:958	arg1	ZICs					972:975	ZICs	972:975	ZICs	972:975	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	0	64	from	mechanism	67:75	arg1	storage					114:120	capacitive energy storage	96:120	capacitive energy storage	96:120	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	5	65	contain	possess	860:866	arg2	content					880:886	high oxygen content	868:886	high oxygen content (17.6 at%)	868:897	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	65	contain	possess	860:866	arg1	materials					826:834	The materials	822:834	The materials prepared by this method	822:858	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	65	contain	possess	860:866	arg2	%					896:896	17.6 at%	889:896	17.6 at%	889:896	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	65	contain	possess	860:866	arg2	g-1					940:942	384.4 m2 g-1	931:942	384.4 m2 g-1	931:942	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	65	contain	possess	860:866	arg2	area					925:928	high specific surface area	903:928	high specific surface area (384.4 m2 g-1)	903:943	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	4	66	theme	stable	750:755	arg1	carbon					790:795	a stable SA-derived interconnected porous carbon	748:795	a stable SA-derived interconnected porous carbon	748:795	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	0	67	theme	alginate-derived	7:22	arg1	carbon					31:36	Sodium alginate-derived porous carbon	0:36	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.	0:121	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	5	68	theme	specific	908:915	arg1	area					925:928	high specific surface area	903:928	high specific surface area (384.4 m2 g-1)	903:943	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	5	68	theme	specific	908:915	arg1	g-1					940:942	384.4 m2 g-1	931:942	384.4 m2 g-1	931:942	The materials prepared by this method possess high oxygen content (17.6 at%) and high specific surface area (384.4 m2 g-1).					
35429707	6	69	theme	superior	1034:1041	arg1	densities					1050:1058	superior energy densities	1034:1058	superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1	1034:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	2	70	theme	few	435:437	arg1	studies					439:445	few studies	435:445	few studies for the mechanism for SA carbonization	435:484	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	4	71	theme	carbon	723:728	arg1	mechanism					699:707	the carbonization mechanism	681:707	the carbonization mechanism of SA-derived carbon	681:728	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	2	72	dep	structure	373:381	arg1	the					369:371	the	369:371	the	369:371	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	3	73	from	mechanism	581:589	arg1	process					598:604	the process	594:604	the process of SA pyrolysis	594:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	0	74	theme	Self-template	39:51	arg1	mechanism					67:75	Self-template carbonization mechanism	39:75	Self-template carbonization mechanism	39:75	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	7	75	theme	alginate	1237:1244	arg1	mechanism					1217:1225	the carbonization mechanism	1199:1225	the carbonization mechanism of sodium alginate	1199:1244	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	3	76	theme	pyrolysis	612:620	arg1	process					598:604	the process	594:604	the process of SA pyrolysis	594:620	In this work, the carbon skeleton cross-linking mode, heteroatom doping and defect generation mechanism in the process of SA pyrolysis are clarified.					
35429707	4	77	theme	self-template	800:812	arg1	method					814:819	self-template method	800:819	self-template method	800:819	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	2	78	theme	product	406:412	arg1	composition					387:397	composition	387:397	composition	387:397	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	78	theme	product	406:412	arg1	structure					373:381	structure	373:381	structure	373:381	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	4	79	link	SA-derived	757:766	arg1	carbon					790:795	a stable SA-derived interconnected porous carbon	748:795	a stable SA-derived interconnected porous carbon	748:795	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	0	80	dep	carbon	31:36	arg1	application					81:91	application	81:91	application in capacitive energy storage	81:120	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	0	80	dep	carbon	31:36	arg1	mechanism					67:75	Self-template carbonization mechanism	39:75	Self-template carbonization mechanism	39:75	Sodium alginate-derived porous carbon: Self-template carbonization mechanism and application in capacitive energy storage.					
35429707	7	81	theme	carbonization	1203:1215	arg1	mechanism					1217:1225	the carbonization mechanism	1199:1225	the carbonization mechanism of sodium alginate	1199:1244	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	4	82	theme	interconnected	768:781	arg1	carbon					790:795	a stable SA-derived interconnected porous carbon	748:795	a stable SA-derived interconnected porous carbon	748:795	Subsequently, based on the understanding of the carbonization mechanism of SA-derived carbon, we have prepared a stable SA-derived interconnected porous carbon by self-template method.					
35429707	2	83	theme	weight	340:345	arg1	precursor					248:256	a carbon precursor	239:256	a carbon precursor	239:256	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	2	83	theme	weight	340:345	arg1	advantages					283:292	the advantages	279:292	the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product	279:412	As a carbon precursor, sodium alginate has the advantages of clear molecular structure, small molecular weight, and easy controls of the structure and composition of the product, but there have been few studies for the mechanism for SA carbonization.					
35429707	7	84	from	prospects	1276:1284	arg1	ZICs					1308:1311	ZICs	1308:1311	ZICs	1308:1311	This work deeply explained the carbonization mechanism of sodium alginate and evaluated the application prospects of SA-based carbon in ZICs comprehensively.					
35429707	6	85	theme	cathode	1070:1076	arg1	mass					1078:1081	cathode mass	1070:1081	cathode mass	1070:1081	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
35429707	6	86	theme	energy	1043:1048	arg1	densities					1050:1058	superior energy densities	1034:1058	superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1	1034:1109	Zn-ion hybrid capacitors (ZICs) device assembled with SA-derived porous carbon performs superior energy densities (based on cathode mass) of 78.35 and 35.56 Wh kg-1 at the power densities of 160 and 5120 W kg-1, respectively.					
36462400	2	0	theme	industrial	384:393	arg1	byproducts					395:404	industrial byproducts	384:404	industrial byproducts	384:404	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	2	0	theme	industrial	384:393	arg1	products					421:428	value-added products	409:428	value-added products	409:428	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	1	1	theme	glycosidic	257:266	arg1	bonds					268:272	glycosidic bonds	257:272	glycosidic bonds	257:272	Oligosaccharides are carbohydrates made of three to twenty monosaccharide units linked through glycosidic bonds.					
36462400	8	2	theme	IC-MS	1267:1271	arg1	system					1273:1278	the IC-MS system	1263:1278	the IC-MS system	1263:1278	The data acquired by the IC-MS system were also compared with previously published LC-MS data.					
36462400	6	3	theme	chromatographic	914:928	arg1	separation					930:939	the ion chromatographic separation	906:939	the ion chromatographic separation	906:939	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	7	4	theme	oligosaccharides	1117:1132	arg1	presence					1194:1201	the presence	1190:1201	the presence of sugar alditols and hexuronic acids	1190:1239	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	4	theme	oligosaccharides	1117:1132	arg1	identification					1099:1112	the identification	1095:1112	the identification of oligosaccharides with structural modifications including methylation	1095:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	4	5	theme	grape	596:600	arg1	marc					602:605	Chardonnay grape marc	585:605	Chardonnay grape marc	585:605	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	6	6	theme	ion	910:912	arg1	separation					930:939	the ion chromatographic separation	906:939	the ion chromatographic separation	906:939	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	2	7	theme	potential	302:310	arg1	activity					322:329	the potential prebiotic activity	298:329	the potential prebiotic activity of oligosaccharides	298:349	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	6	8	theme	small	1022:1026	arg1	oligosaccharides					1037:1052	small, neutral oligosaccharides	1022:1052	small, neutral oligosaccharides	1022:1052	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	5	9	with	oligosaccharides	801:816	arg1	compositions					830:841	unique compositions	823:841	unique compositions of monosaccharides	823:860	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	9	10	from	combination	1405:1415	arg1	complementary					1383:1395	complementary	1383:1395	complementary	1383:1395	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	5	11	theme	oligosaccharide	869:883	arg1	structures					885:894	61 oligosaccharide structures	866:894	61 oligosaccharide structures	866:894	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	7	12	theme	sugar	1206:1210	arg1	alditols					1212:1219	sugar alditols	1206:1219	sugar alditols	1206:1219	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	9	13	from	complementary	1383:1395	arg1	combination					1405:1415	combination	1405:1415	combination	1405:1415	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	7	14	theme	structural	1139:1148	arg1	methylation					1174:1184	methylation	1174:1184	methylation	1174:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	14	theme	structural	1139:1148	arg1	modifications					1150:1162	structural modifications	1139:1162	structural modifications including methylation	1139:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	2	15	theme	oligosaccharides	334:349	arg1	activity					322:329	the potential prebiotic activity	298:329	the potential prebiotic activity of oligosaccharides	298:349	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	5	16	with	structures	885:894	arg1	compositions					830:841	unique compositions	823:841	unique compositions of monosaccharides	823:860	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	3	17	theme	left	455:458	arg1	marc					437:440	Grape marc	431:440	Grape marc	431:440	Grape marc is a residue left after winemaking and has been shown to provide health benefits to humans.					
36462400	3	17	theme	left	455:458	arg1	residue					447:453	a residue	445:453	a residue left after winemaking	445:475	Grape marc is a residue left after winemaking and has been shown to provide health benefits to humans.					
36462400	3	18	theme	Grape	431:435	arg1	marc					437:440	Grape marc	431:440	Grape marc	431:440	Grape marc is a residue left after winemaking and has been shown to provide health benefits to humans.					
36462400	3	18	theme	Grape	431:435	arg1	residue					447:453	a residue	445:453	a residue left after winemaking	445:475	Grape marc is a residue left after winemaking and has been shown to provide health benefits to humans.					
36462400	9	19	dep	platform	1496:1503	arg1	achieves					1505:1512	achieves	1505:1512	achieves alone	1505:1518	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	2	20	theme	value-added	409:419	arg1	byproducts					395:404	industrial byproducts	384:404	industrial byproducts	384:404	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	2	20	theme	value-added	409:419	arg1	products					421:428	value-added products	409:428	value-added products	409:428	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	4	21	from	oligosaccharides	565:580	arg1	marc					602:605	Chardonnay grape marc	585:605	Chardonnay grape marc	585:605	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	6	22	theme	separation	998:1007	arg1	capacity					1009:1016	separation capacity	998:1016	separation capacity for small, neutral oligosaccharides	998:1052	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	0	23	theme	prebiotic	109:117	arg1	oligosaccharides					119:134	potentially prebiotic oligosaccharides	97:134	potentially prebiotic oligosaccharides	97:134	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	5	24	theme	unique	823:828	arg1	compositions					830:841	unique compositions	823:841	unique compositions of monosaccharides	823:860	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	0	25	theme	ion	12:14	arg1	chromatography					16:29	an ion chromatography	9:29	an ion chromatography	9:29	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	4	26	theme	Chardonnay	585:594	arg1	marc					602:605	Chardonnay grape marc	585:605	Chardonnay grape marc	585:605	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	2	27	theme	prebiotic	312:320	arg1	activity					322:329	the potential prebiotic activity	298:329	the potential prebiotic activity of oligosaccharides	298:349	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	0	28	theme	high	34:37	arg1	IC-MS					69:73	IC-MS	69:73	IC-MS	69:73	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	0	28	theme	high	34:37	arg1	spectrometry					55:66	high resolution mass spectrometry	34:66	high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc	34:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	7	29	with	oligosaccharides	1117:1132	arg1	methylation					1174:1184	methylation	1174:1184	methylation	1174:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	29	with	oligosaccharides	1117:1132	arg1	modifications					1150:1162	structural modifications	1139:1162	structural modifications including methylation	1139:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	8	30	theme	published	1315:1323	arg1	data					1331:1334	previously published LC-MS data	1304:1334	previously published LC-MS data	1304:1334	The data acquired by the IC-MS system were also compared with previously published LC-MS data.					
36462400	4	31	theme	chromatography	658:671	arg1	system					678:683	an ion chromatography (IC) system	651:683	an ion chromatography (IC) system	651:683	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	7	32	theme	hexuronic	1225:1233	arg1	acids					1235:1239	hexuronic acids	1225:1239	hexuronic acids	1225:1239	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	6	33	theme	isomers	972:978	arg1	resolution					950:959	resolution	950:959	resolution of charged isomers	950:978	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	0	34	theme	oligosaccharides	119:134	arg1	discovery					84:92	the discovery	80:92	the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc	80:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	7	35	theme	acids	1235:1239	arg1	presence					1194:1201	the presence	1190:1201	the presence of sugar alditols and hexuronic acids	1190:1239	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	35	theme	acids	1235:1239	arg1	identification					1099:1112	the identification	1095:1112	the identification of oligosaccharides with structural modifications including methylation	1095:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	36	theme	High-quality	1055:1066	arg1	MS					1075:1076	High-quality tandem MS	1055:1076	High-quality tandem MS	1055:1076	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	4	37	theme	ion	654:656	arg1	IC					674:675	IC	674:675	IC	674:675	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	4	37	theme	ion	654:656	arg1	chromatography					658:671	ion chromatography	654:671	an ion chromatography (IC) system	651:683	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	0	38	theme	mass	50:53	arg1	IC-MS					69:73	IC-MS	69:73	IC-MS	69:73	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	0	38	theme	mass	50:53	arg1	spectrometry					55:66	high resolution mass spectrometry	34:66	high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc	34:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	6	39	theme	charged	964:970	arg1	isomers					972:978	charged isomers	964:978	charged isomers	964:978	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	0	40	theme	grape	150:154	arg1	marc					156:159	Chardonnay grape marc	139:159	Chardonnay grape marc	139:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	1	41	dep	units	236:240	arg1	to					211:212	to	211:212	to	211:212	Oligosaccharides are carbohydrates made of three to twenty monosaccharide units linked through glycosidic bonds.					
36462400	7	42	theme	tandem	1068:1073	arg1	MS					1075:1076	High-quality tandem MS	1055:1076	High-quality tandem MS	1055:1076	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	4	43	theme	mass	711:714	arg1	MS					730:731	MS	730:731	MS	730:731	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	4	43	theme	mass	711:714	arg1	spectrometer					716:727	an Orbitrap mass spectrometer	699:727	an Orbitrap mass spectrometer (MS)	699:732	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	0	44	theme	resolution	39:48	arg1	IC-MS					69:73	IC-MS	69:73	IC-MS	69:73	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	0	44	theme	resolution	39:48	arg1	spectrometry					55:66	high resolution mass spectrometry	34:66	high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc	34:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	0	45	theme	Chardonnay	139:148	arg1	marc					156:159	Chardonnay grape marc	139:159	Chardonnay grape marc	139:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	4	46	theme	Orbitrap	702:709	arg1	MS					730:731	MS	730:731	MS	730:731	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	4	46	theme	Orbitrap	702:709	arg1	spectrometer					716:727	an Orbitrap mass spectrometer	699:727	an Orbitrap mass spectrometer (MS)	699:732	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
36462400	9	47	theme	comprehensive	1433:1445	arg1	characterization					1447:1462	a more comprehensive characterization	1426:1462	a more comprehensive characterization of oligosaccharides than either platform achieves alone	1426:1518	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	7	48	theme	alditols	1212:1219	arg1	presence					1194:1201	the presence	1190:1201	the presence of sugar alditols and hexuronic acids	1190:1239	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	7	48	theme	alditols	1212:1219	arg1	identification					1099:1112	the identification	1095:1112	the identification of oligosaccharides with structural modifications including methylation	1095:1184	High-quality tandem MS also facilitated the identification of oligosaccharides with structural modifications including methylation and the presence of sugar alditols and hexuronic acids.					
36462400	0	49	from	discovery	84:92	arg1	marc					156:159	Chardonnay grape marc	139:159	Chardonnay grape marc	139:159	Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc.					
36462400	2	50	theme	Emerging	275:282	arg1	research					284:291	Emerging research	275:291	Emerging research into the potential prebiotic activity of oligosaccharides	275:349	Emerging research into the potential prebiotic activity of oligosaccharides is creating opportunities to use industrial byproducts as value-added products.					
36462400	8	51	theme	LC-MS	1325:1329	arg1	data					1331:1334	previously published LC-MS data	1304:1334	previously published LC-MS data	1304:1334	The data acquired by the IC-MS system were also compared with previously published LC-MS data.					
36462400	9	52	dep	complementary	1383:1395	arg1	provide					1418:1424	provide	1418:1424	provide a more comprehensive characterization of oligosaccharides than either platform achieves alone	1418:1518	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	1	53	theme	monosaccharide	221:234	arg1	units					236:240	three to twenty monosaccharide units	205:240	three to twenty monosaccharide units linked through glycosidic bonds	205:272	Oligosaccharides are carbohydrates made of three to twenty monosaccharide units linked through glycosidic bonds.					
36462400	3	54	theme	health	507:512	arg1	benefits					514:521	health benefits	507:521	health benefits to humans	507:531	Grape marc is a residue left after winemaking and has been shown to provide health benefits to humans.					
36462400	5	55	theme	monosaccharides	846:860	arg1	compositions					830:841	unique compositions	823:841	unique compositions of monosaccharides	823:860	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	9	56	theme	oligosaccharides	1467:1482	arg1	characterization					1447:1462	a more comprehensive characterization	1426:1462	a more comprehensive characterization of oligosaccharides than either platform achieves alone	1426:1518	We found that these two platforms are largely complementary and, in combination, provide a more comprehensive characterization of oligosaccharides than either platform achieves alone.					
36462400	5	57	theme	structural	769:778	arg1	library					780:786	a structural library	767:786	a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures	767:894	With this platform, we obtained a structural library including 32 oligosaccharides with unique compositions of monosaccharides and 61 oligosaccharide structures.					
36462400	6	58	dep	small	1022:1026	arg1	neutral					1029:1035	neutral	1029:1035	neutral	1029:1035	Notably, the ion chromatographic separation provided resolution of charged isomers while maintaining separation capacity for small, neutral oligosaccharides.					
36462400	4	59	theme	hyphenated	622:631	arg1	platform					633:640	a hyphenated platform	620:640	a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS)	620:732	In this study, we analyzed the oligosaccharides in Chardonnay grape marc by utilizing a hyphenated platform in which an ion chromatography (IC) system is coupled to an Orbitrap mass spectrometer (MS).					
35230555	0	0	theme	fuel	95:98	arg1	cell					100:103	microbial fuel cell	85:103	microbial fuel cell	85:103	Effect of β-cyclodextrin/polydopamine composite modified anode on the performance of microbial fuel cell.					
35230555	0	1	theme	microbial	85:93	arg1	cell					100:103	microbial fuel cell	85:103	microbial fuel cell	85:103	Effect of β-cyclodextrin/polydopamine composite modified anode on the performance of microbial fuel cell.					
35230555	5	2	theme	overall	1016:1022	arg1	performance					1024:1034	the overall performance	1012:1034	the overall performance of MFC	1012:1041	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	3	3	theme	modified	354:361	arg1	anode					375:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	4	theme	anode	375:379	arg1	type					318:321	A new type	312:321	A new type of β-cyclodextrin/polydopamine modified carbon felt anode	312:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	5	theme	carbon	363:368	arg1	anode					375:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	2	6	theme	effective	272:280	arg1	modification					243:254	Anode modification	237:254	Anode modification	237:254	Anode modification is a simple and effective method to solve this problem.					
35230555	2	6	theme	effective	272:280	arg1	method					282:287	a simple and effective method	259:287	a simple and effective method to solve this problem	259:309	Anode modification is a simple and effective method to solve this problem.					
35230555	5	7	theme	MFC	1039:1041	arg1	performance					1024:1034	the overall performance	1012:1034	the overall performance of MFC	1012:1041	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	4	8	theme	carbon	790:795	arg1	anode					802:806	conventional carbon felt anode	777:806	conventional carbon felt anode	777:806	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	1	9	theme	microbial	210:218	arg1	MFC					231:233	MFC	231:233	MFC	231:233	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	1	9	theme	microbial	210:218	arg1	cell					225:228	microbial fuel cell	210:228	microbial fuel cell (MFC)	210:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	3	10	theme	modified	442:449	arg1	anode					451:455	β-cyclodextrin/polydopamine modified anode	414:455	β-cyclodextrin/polydopamine modified anode	414:455	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	11	theme	β-cyclodextrin/polydopamine	326:352	arg1	anode					375:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	4	12	theme	conventional	777:788	arg1	anode					802:806	conventional carbon felt anode	777:806	conventional carbon felt anode	777:806	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	2	13	theme	simple	261:266	arg1	modification					243:254	Anode modification	237:254	Anode modification	237:254	Anode modification is a simple and effective method to solve this problem.					
35230555	2	13	theme	simple	261:266	arg1	method					282:287	a simple and effective method	259:287	a simple and effective method to solve this problem	259:309	Anode modification is a simple and effective method to solve this problem.					
35230555	1	14	theme	power	178:182	arg1	performance					195:205	the power generation performance	174:205	the power generation performance of microbial fuel cell (MFC)	174:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	4	15	theme	unmodified	888:897	arg1	anode					899:903	unmodified anode	888:903	unmodified anode	888:903	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	3	16	dep	density	503:509	arg1	rate					552:555	removal rate	544:555	removal rate	544:555	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	1	17	theme	generation	184:193	arg1	performance					195:205	the power generation performance	174:205	the power generation performance of microbial fuel cell (MFC)	174:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	4	18	theme	felt	797:800	arg1	anode					802:806	conventional carbon felt anode	777:806	conventional carbon felt anode	777:806	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	3	19	theme	MFC	560:562	arg1	COD					539:541	COD	539:541	COD	539:541	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	19	theme	MFC	560:562	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	19	theme	MFC	560:562	arg1	density					503:509	power density	497:509	power density	497:509	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	20	theme	β-cyclodextrin/polydopamine	414:440	arg1	anode					451:455	β-cyclodextrin/polydopamine modified anode	414:455	β-cyclodextrin/polydopamine modified anode	414:455	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	21	theme	felt	370:373	arg1	anode					375:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	β-cyclodextrin/polydopamine modified carbon felt anode	326:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	22	theme	removal	544:550	arg1	rate					552:555	removal rate	544:555	removal rate	544:555	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	23	theme	main	464:467	arg1	indexes					481:487	the main performance indexes	460:487	the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC	460:562	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	23	theme	main	464:467	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	23	theme	main	464:467	arg1	density					503:509	power density	497:509	power density	497:509	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	0	24	theme	β-cyclodextrin/polydopamine	10:36	arg1	composite					38:46	β-cyclodextrin/polydopamine composite	10:46	β-cyclodextrin/polydopamine composite	10:46	Effect of β-cyclodextrin/polydopamine composite modified anode on the performance of microbial fuel cell.					
35230555	3	25	theme	performance	469:479	arg1	indexes					481:487	the main performance indexes	460:487	the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC	460:562	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	25	theme	performance	469:479	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	25	theme	performance	469:479	arg1	density					503:509	power density	497:509	power density	497:509	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	26	theme	power	497:501	arg1	density					503:509	power density	497:509	power density	497:509	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	5	27	with	anode	920:924	arg1	materials					968:976	β-cyclodextrin-polyacyclic composite materials	931:976	β-cyclodextrin-polyacyclic composite materials	931:976	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	5	28	theme	β-cyclodextrin-polyacyclic	931:956	arg1	materials					968:976	β-cyclodextrin-polyacyclic composite materials	931:976	β-cyclodextrin-polyacyclic composite materials	931:976	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	4	29	theme	test	648:651	arg1	period					653:658	the test period	644:658	the test period of MFC	644:665	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	1	30	theme	fuel	220:223	arg1	MFC					231:233	MFC	231:233	MFC	231:233	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	1	30	theme	fuel	220:223	arg1	cell					225:228	microbial fuel cell	210:228	microbial fuel cell (MFC)	210:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	4	31	theme	MFC	663:665	arg1	period					653:658	the test period	644:658	the test period of MFC	644:665	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	32	theme	modified	677:684	arg1	anode					686:690	the modified anode	673:690	the modified anode	673:690	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	0	33	theme	composite	38:46	arg1	Effect					0:5	Effect	0:5	Effect of β-cyclodextrin/polydopamine composite	0:46	Effect of β-cyclodextrin/polydopamine composite modified anode on the performance of microbial fuel cell.					
35230555	1	34	theme	cell	225:228	arg1	performance					195:205	the power generation performance	174:205	the power generation performance of microbial fuel cell (MFC)	174:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	4	35	theme	COD	831:833	arg1	rate					843:846	the COD removal rate	827:846	the COD removal rate	827:846	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	35	theme	COD	831:833	arg1	higher					859:864	higher	859:864	higher	859:864	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	1	36	theme	weak	121:124	arg1	adhesion					136:143	The relatively weak microbial adhesion	106:143	The relatively weak microbial adhesion	106:143	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	1	36	theme	weak	121:124	arg1	bottleneck					150:159	a bottleneck	148:159	a bottleneck in improving the power generation performance of microbial fuel cell (MFC)	148:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	3	37	from	effects	403:409	arg1	indexes					481:487	the main performance indexes	460:487	the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC	460:562	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	37	from	effects	403:409	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	37	from	effects	403:409	arg1	density					503:509	power density	497:509	power density	497:509	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	1	38	theme	microbial	126:134	arg1	adhesion					136:143	The relatively weak microbial adhesion	106:143	The relatively weak microbial adhesion	106:143	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	1	38	theme	microbial	126:134	arg1	bottleneck					150:159	a bottleneck	148:159	a bottleneck in improving the power generation performance of microbial fuel cell (MFC)	148:234	The relatively weak microbial adhesion is a bottleneck in improving the power generation performance of microbial fuel cell (MFC).					
35230555	5	39	theme	effective	984:992	arg1	method					994:999	an effective method	981:999	an effective method to improve the overall performance of MFC	981:1041	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	5	40	theme	composite	958:966	arg1	materials					968:976	β-cyclodextrin-polyacyclic composite materials	931:976	β-cyclodextrin-polyacyclic composite materials	931:976	Modifying the anode with β-cyclodextrin-polyacyclic composite materials is an effective method to improve the overall performance of MFC.					
35230555	4	41	theme	power	592:596	arg1	density					598:604	The maximum power density	580:604	The maximum power density	580:604	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	41	theme	power	592:596	arg1	102 mW/m2					697:705	102 mW/m2	697:705	102 mW/m2	697:705	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	42	theme	removal	835:841	arg1	rate					843:846	the COD removal rate	827:846	the COD removal rate	827:846	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	42	theme	removal	835:841	arg1	higher					859:864	higher	859:864	higher	859:864	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	43	with	MFC	879:881	arg1	anode					899:903	unmodified anode	888:903	unmodified anode	888:903	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	44	theme	maximum	584:590	arg1	density					598:604	The maximum power density	580:604	The maximum power density	580:604	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	44	theme	maximum	584:590	arg1	102 mW/m2					697:705	102 mW/m2	697:705	102 mW/m2	697:705	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	3	45	theme	new	314:316	arg1	type					318:321	A new type	312:321	A new type of β-cyclodextrin/polydopamine modified carbon felt anode	312:379	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	4	46	theme	electric	621:628	arg1	energy					630:635	the output electric energy	610:635	the output electric energy during the test period of MFC	610:665	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	46	theme	electric	621:628	arg1	102 mW/m2					697:705	102 mW/m2	697:705	102 mW/m2	697:705	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	47	theme	output	614:619	arg1	energy					630:635	the output electric energy	610:635	the output electric energy during the test period of MFC	610:665	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	4	47	theme	output	614:619	arg1	102 mW/m2					697:705	102 mW/m2	697:705	102 mW/m2	697:705	The maximum power density and the output electric energy during the test period of MFC using the modified anode were 102 mW/m2 and 84.96 J, which were 364% and 295.3% higher than those of MFC with conventional carbon felt anode, respectively; and the COD removal rate was 124.4% higher than that of MFC with unmodified anode.					
35230555	3	48	theme	chemical	515:522	arg1	COD					539:541	COD	539:541	COD	539:541	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	48	theme	chemical	515:522	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	49	theme	anode	451:455	arg1	effects					403:409	the effects	399:409	the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC	399:562	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	2	50	theme	Anode	237:241	arg1	modification					243:254	Anode modification	237:254	Anode modification	237:254	Anode modification is a simple and effective method to solve this problem.					
35230555	2	50	theme	Anode	237:241	arg1	method					282:287	a simple and effective method	259:287	a simple and effective method to solve this problem	259:309	Anode modification is a simple and effective method to solve this problem.					
35230555	3	51	theme	oxygen	524:529	arg1	COD					539:541	COD	539:541	COD	539:541	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	3	51	theme	oxygen	524:529	arg1	demand					531:536	chemical oxygen demand	515:536	chemical oxygen demand (COD)	515:542	A new type of β-cyclodextrin/polydopamine modified carbon felt anode was prepared, and the effects of β-cyclodextrin/polydopamine modified anode on the main performance indexes such as power density and chemical oxygen demand (COD) removal rate of MFC were evaluated.					
35230555	0	52	theme	cell	100:103	arg1	performance					70:80	the performance	66:80	the performance of microbial fuel cell	66:103	Effect of β-cyclodextrin/polydopamine composite modified anode on the performance of microbial fuel cell.					
36063778	9	0	from	scale	1356:1360	arg1	variations					1328:1337	Process variations	1320:1337	Process variations at manufacturing scale of 94 runs	1320:1371	Process variations at manufacturing scale of 94 runs were adequately reproduced by the model.					
36063778	6	1	theme	mean-field	1003:1012	arg1	approach					1014:1021	a mean-field approach	1001:1021	a mean-field approach considering interactions between the protein of interest and other ions in solution	1001:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	11	2	theme	operating	1723:1731	arg1	units					1733:1737	operating units	1723:1737	operating units	1723:1737	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	10	3	theme	concentration	1483:1495	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	4	4	theme	ion	698:700	arg1	steps					726:730	The polishing ion exchange chromatography steps	684:730	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS)	684:760	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	11	5	theme	integrated	1636:1645	arg1	approach					1647:1654	the integrated approach	1632:1654	the integrated approach	1632:1654	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	3	6	theme	digital	614:620	arg1	representations					622:636	digital representations	614:636	digital representations of a biopharmaceutical manufacturing process	614:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	3	6	theme	digital	614:620	arg1	models					574:579	state-of-the-art mechanistic models	545:579	state-of-the-art mechanistic models	545:579	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	6	7	theme	pH	965:966	arg1	adjustments					968:978	pH adjustments	965:978	pH adjustments	965:978	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	10	8	theme	size	1498:1501	arg1	variant					1503:1509	size variant	1498:1509	size variant	1498:1509	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	3	9	theme	process	675:681	arg1	representations					622:636	digital representations	614:636	digital representations of a biopharmaceutical manufacturing process	614:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	3	9	theme	process	675:681	arg1	models					574:579	state-of-the-art mechanistic models	545:579	state-of-the-art mechanistic models	545:579	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	6	10	theme	interest	1071:1078	arg1	protein					1060:1066	the protein	1056:1066	the protein of interest and other ions in solution	1056:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	4	11	theme	Sepharose	735:743	arg1	FF					745:746	Q Sepharose FF	733:746	Q Sepharose FF	733:746	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	4	11	theme	Sepharose	735:743	arg1	HS					758:759	Poros 50 HS	749:759	Poros 50 HS	749:759	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	9	12	theme	Process	1320:1326	arg1	variations					1328:1337	Process variations	1320:1337	Process variations at manufacturing scale of 94 runs	1320:1371	Process variations at manufacturing scale of 94 runs were adequately reproduced by the model.					
36063778	3	13	theme	biopharmaceutical	643:659	arg1	process					675:681	a biopharmaceutical manufacturing process	641:681	a biopharmaceutical manufacturing process	641:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	7	14	theme	process	1152:1158	arg1	inputs					1168:1173	the important process control inputs	1138:1173	the important process control inputs ionic strength, dilution, and pH	1138:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	14	theme	process	1152:1158	arg1	dilution					1191:1198	dilution	1191:1198	dilution	1191:1198	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	14	theme	process	1152:1158	arg1	pH					1205:1206	pH	1205:1206	pH	1205:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	14	theme	process	1152:1158	arg1	strength					1181:1188	ionic strength	1175:1188	ionic strength	1175:1188	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	2	15	theme	holistic	294:301	arg1	model					311:315	A holistic process model	292:315	A holistic process model based on mechanistic insights	292:345	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	0	16	theme	manufacturing	65:77	arg1	chromatography					79:92	biopharmaceutical manufacturing chromatography and adjustment steps	47:113	chromatography	79:92	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36063778	1	17	theme	downstream	165:174	arg1	process					176:182	an entire downstream process	155:182	an entire downstream process	155:182	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	10	18	theme	volume	1532:1537	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	11	19	theme	presented	1586:1594	arg1	model					1596:1600	The presented model	1582:1600	The presented model	1582:1600	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	5	20	theme	elution	866:872	arg1	behavior					874:881	The elution behavior	862:881	The elution behavior of four size variants	862:903	The elution behavior of four size variants was analyzed and included in the model.					
36063778	10	21	theme	composition	1519:1529	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	0	22	theme	steps	109:113	arg1	prediction					33:42	the prediction	29:42	the prediction of biopharmaceutical manufacturing chromatography and adjustment steps	29:113	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36063778	6	23	theme	other	1084:1088	arg1	ions					1090:1093	other ions	1084:1093	other ions in solution	1084:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	6	24	from	ions	1090:1093	arg1	solution					1098:1105	solution	1098:1105	solution	1098:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	6	25	from	solution	1098:1105	arg1	protein					1060:1066	the protein	1056:1066	the protein of interest and other ions in solution	1056:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	4	26	theme	colloidal	825:833	arg1	model					855:859	a colloidal particle adsorption model	823:859	a colloidal particle adsorption model	823:859	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	2	27	theme	quality	449:455	arg1	attributes					457:466	critical quality attributes	440:466	critical quality attributes	440:466	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	2	28	theme	holistic	503:510	arg1	strategy					520:527	a holistic control strategy	501:527	a holistic control strategy	501:527	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	4	29	theme	adsorption	844:853	arg1	model					855:859	a colloidal particle adsorption model	823:859	a colloidal particle adsorption model	823:859	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	1	30	theme	fundamental	118:128	arg1	essential					187:195	essential	187:195	essential	187:195	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	1	30	theme	fundamental	118:128	arg1	understanding					138:150	A fundamental process understanding	116:150	A fundamental process understanding of an entire downstream process	116:182	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	6	31	theme	Titration	945:953	arg1	curves					955:960	Titration curves	945:960	Titration curves of pH adjustments	945:978	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	11	32	theme	process	1685:1691	arg1	performance					1693:1703	manufacturing process performance	1671:1703	manufacturing process performance	1671:1703	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	3	33	theme	mechanistic	562:572	arg1	representations					622:636	digital representations	614:636	digital representations of a biopharmaceutical manufacturing process	614:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	3	33	theme	mechanistic	562:572	arg1	models					574:579	state-of-the-art mechanistic models	545:579	state-of-the-art mechanistic models	545:579	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	5	34	theme	size	891:894	arg1	variants					896:903	four size variants	886:903	four size variants	886:903	The elution behavior of four size variants was analyzed and included in the model.					
36063778	11	35	theme	manufacturing	1671:1683	arg1	performance					1693:1703	manufacturing process performance	1671:1703	manufacturing process performance	1671:1703	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	4	36	theme	exchange	702:709	arg1	steps					726:730	The polishing ion exchange chromatography steps	684:730	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS)	684:760	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	10	37	theme	20	1460:1461	arg1	%					1462:1462	%	1462:1462	%	1462:1462	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	1	38	theme	biopharmaceutical	267:283	arg1	drugs					285:289	biopharmaceutical drugs	267:289	biopharmaceutical drugs	267:289	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	2	39	theme	process	417:423	arg1	parameters					425:434	process parameters	417:434	process parameters	417:434	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	8	40	theme	process	1235:1241	arg1	capable					1253:1259	capable	1253:1259	capable	1253:1259	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	8	40	theme	process	1235:1241	arg1	model					1243:1247	The final process model	1225:1247	The final process model	1225:1247	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	11	41	theme	approach	1647:1654	arg1	potential					1619:1627	the potential	1615:1627	the potential of the integrated approach for predicting manufacturing process performance across scales and operating units	1615:1737	The presented model demonstrates the potential of the integrated approach for predicting manufacturing process performance across scales and operating units.					
36063778	2	42	theme	mechanistic	326:336	arg1	insights					338:345	mechanistic insights	326:345	mechanistic insights	326:345	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	3	43	theme	manufacturing	661:673	arg1	process					675:681	a biopharmaceutical manufacturing process	641:681	a biopharmaceutical manufacturing process	641:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	4	44	theme	polishing	688:696	arg1	steps					726:730	The polishing ion exchange chromatography steps	684:730	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS)	684:760	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	10	45	theme	input	1464:1468	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	6	46	theme	adjustments	968:978	arg1	curves					955:960	Titration curves	945:960	Titration curves of pH adjustments	945:978	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	4	47	theme	Poros	749:753	arg1	FF					745:746	Q Sepharose FF	733:746	Q Sepharose FF	733:746	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	4	47	theme	Poros	749:753	arg1	HS					758:759	Poros 50 HS	749:759	Poros 50 HS	749:759	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	10	48	theme	variant	1503:1509	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	2	49	theme	process	361:367	arg1	development					369:379	process development	361:379	process development	361:379	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	8	50	theme	online	1272:1277	arg1	data					1291:1294	online and offline data	1272:1294	online and offline data	1272:1294	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	7	51	theme	ionic	1175:1179	arg1	inputs					1168:1173	the important process control inputs	1138:1173	the important process control inputs ionic strength, dilution, and pH	1138:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	51	theme	ionic	1175:1179	arg1	strength					1181:1188	ionic strength	1175:1188	ionic strength	1175:1188	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	8	52	theme	offline	1283:1289	arg1	data					1291:1294	online and offline data	1272:1294	online and offline data	1272:1294	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	4	53	theme	Q	733:733	arg1	FF					745:746	Q Sepharose FF	733:746	Q Sepharose FF	733:746	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	4	53	theme	Q	733:733	arg1	HS					758:759	Poros 50 HS	749:759	Poros 50 HS	749:759	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	7	54	theme	control	1160:1166	arg1	inputs					1168:1173	the important process control inputs	1138:1173	the important process control inputs ionic strength, dilution, and pH	1138:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	54	theme	control	1160:1166	arg1	dilution					1191:1198	dilution	1191:1198	dilution	1191:1198	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	54	theme	control	1160:1166	arg1	pH					1205:1206	pH	1205:1206	pH	1205:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	54	theme	control	1160:1166	arg1	strength					1181:1188	ionic strength	1175:1188	ionic strength	1175:1188	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	1	55	theme	high-quality	231:242	arg1	standards					244:252	the high-quality standards	227:252	the high-quality standards demanded for biopharmaceutical drugs	227:289	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	7	56	theme	important	1142:1150	arg1	inputs					1168:1173	the important process control inputs	1138:1173	the important process control inputs ionic strength, dilution, and pH	1138:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	56	theme	important	1142:1150	arg1	dilution					1191:1198	dilution	1191:1198	dilution	1191:1198	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	56	theme	important	1142:1150	arg1	pH					1205:1206	pH	1205:1206	pH	1205:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	56	theme	important	1142:1150	arg1	strength					1181:1188	ionic strength	1175:1188	ionic strength	1175:1188	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	9	57	theme	manufacturing	1342:1354	arg1	scale					1356:1360	manufacturing scale	1342:1360	manufacturing scale of 94 runs	1342:1371	Process variations at manufacturing scale of 94 runs were adequately reproduced by the model.					
36063778	7	58	theme	adjustment	1121:1130	arg1	steps					1132:1136	adjustment steps	1121:1136	adjustment steps	1121:1136	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	1	59	theme	process	130:136	arg1	essential					187:195	essential	187:195	essential	187:195	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	1	59	theme	process	130:136	arg1	understanding					138:150	A fundamental process understanding	116:150	A fundamental process understanding of an entire downstream process	116:182	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	4	60	theme	transport-dispersive	782:801	arg1	model					803:807	a transport-dispersive model	780:807	a transport-dispersive model combined with a colloidal particle adsorption model	780:859	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	4	61	dep	steps	726:730	arg1	FF					745:746	Q Sepharose FF	733:746	Q Sepharose FF	733:746	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	4	61	dep	steps	726:730	arg1	HS					758:759	Poros 50 HS	749:759	Poros 50 HS	749:759	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	2	62	theme	process	303:309	arg1	model					311:315	A holistic process model	292:315	A holistic process model based on mechanistic insights	292:345	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	0	63	theme	chromatography	79:92	arg1	prediction					33:42	the prediction	29:42	the prediction of biopharmaceutical manufacturing chromatography and adjustment steps	29:113	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36063778	9	64	theme	runs	1368:1371	arg1	scale					1356:1360	manufacturing scale	1342:1360	manufacturing scale of 94 runs	1342:1371	Process variations at manufacturing scale of 94 runs were adequately reproduced by the model.					
36063778	1	65	theme	entire	158:163	arg1	process					176:182	an entire downstream process	155:182	an entire downstream process	155:182	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	0	66	theme	adjustment	98:107	arg1	steps					109:113	biopharmaceutical manufacturing chromatography and adjustment steps	47:113	steps	109:113	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36063778	1	67	theme	process	176:182	arg1	essential					187:195	essential	187:195	essential	187:195	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	1	67	theme	process	176:182	arg1	understanding					138:150	A fundamental process understanding	116:150	A fundamental process understanding of an entire downstream process	116:182	A fundamental process understanding of an entire downstream process is essential for achieving and maintaining the high-quality standards demanded for biopharmaceutical drugs.					
36063778	6	68	theme	ions	1090:1093	arg1	protein					1060:1066	the protein	1056:1066	the protein of interest and other ions in solution	1056:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	10	69	theme	ion	1515:1517	arg1	composition					1519:1529	ion composition	1515:1529	ion composition	1515:1529	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	10	70	theme	pH	1544:1545	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	5	71	theme	variants	896:903	arg1	behavior					874:881	The elution behavior	862:881	The elution behavior of four size variants	862:903	The elution behavior of four size variants was analyzed and included in the model.					
36063778	2	72	theme	control	512:518	arg1	strategy					520:527	a holistic control strategy	501:527	a holistic control strategy	501:527	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	2	73	theme	critical	440:447	arg1	attributes					457:466	critical quality attributes	440:466	critical quality attributes	440:466	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	6	74	from	protein	1060:1066	arg1	solution					1098:1105	solution	1098:1105	solution	1098:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	4	75	theme	particle	835:842	arg1	model					855:859	a colloidal particle adsorption model	823:859	a colloidal particle adsorption model	823:859	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	6	76	from	interest	1071:1078	arg1	solution					1098:1105	solution	1098:1105	solution	1098:1105	Titration curves of pH adjustments were simulated using a mean-field approach considering interactions between the protein of interest and other ions in solution.					
36063778	10	77	theme	robustness	1439:1448	arg1	process					1431:1437	the process	1427:1437	the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH	1427:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	2	78	theme	unit	475:478	arg1	operations					480:489	unit operations	475:489	unit operations	475:489	A holistic process model based on mechanistic insights could support process development by identifying dependencies between process parameters and critical quality attributes across unit operations to design a holistic control strategy.					
36063778	0	79	theme	biopharmaceutical	47:63	arg1	chromatography					79:92	biopharmaceutical manufacturing chromatography and adjustment steps	47:113	chromatography	79:92	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36063778	4	80	theme	chromatography	711:724	arg1	steps					726:730	The polishing ion exchange chromatography steps	684:730	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS)	684:760	The polishing ion exchange chromatography steps (Q Sepharose FF, Poros 50 HS) were described by a transport-dispersive model combined with a colloidal particle adsorption model.					
36063778	10	81	theme	%	1462:1462	arg1	variation					1470:1478	a 20% input variation	1458:1478	a 20% input variation of concentration, size variant and ion composition, volume, and pH	1458:1545	Furthermore, the process robustness against a 20% input variation of concentration, size variant and ion composition, volume, and pH could be confirmed with the model.					
36063778	3	82	theme	state-of-the-art	545:560	arg1	representations					622:636	digital representations	614:636	digital representations of a biopharmaceutical manufacturing process	614:681	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	3	82	theme	state-of-the-art	545:560	arg1	models					574:579	state-of-the-art mechanistic models	545:579	state-of-the-art mechanistic models	545:579	In this study, state-of-the-art mechanistic models were calibrated and validated as digital representations of a biopharmaceutical manufacturing process.					
36063778	8	83	theme	final	1229:1233	arg1	capable					1253:1259	capable	1253:1259	capable	1253:1259	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	8	83	theme	final	1229:1233	arg1	model					1243:1247	The final process model	1225:1247	The final process model	1225:1247	The final process model was capable to predict online and offline data at manufacturing scale.					
36063778	7	84	dep	inputs	1168:1173	arg1	inputs					1168:1173	the important process control inputs	1138:1173	the important process control inputs ionic strength, dilution, and pH	1138:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	84	dep	inputs	1168:1173	arg1	dilution					1191:1198	dilution	1191:1198	dilution	1191:1198	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	84	dep	inputs	1168:1173	arg1	pH					1205:1206	pH	1205:1206	pH	1205:1206	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	7	84	dep	inputs	1168:1173	arg1	strength					1181:1188	ionic strength	1175:1188	ionic strength	1175:1188	By including adjustment steps the important process control inputs ionic strength, dilution, and pH were integrated.					
36063778	0	85	theme	process	11:17	arg1	model					19:23	process model	11:23	process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps	11:113	Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.					
36586654	4	0	theme	thermogravimetric	887:903	arg1	TGA					915:917	TGA	915:917	TGA	915:917	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	4	0	theme	thermogravimetric	887:903	arg1	analysis					905:912	thermogravimetric analysis	887:912	thermogravimetric analysis (TGA)	887:918	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	7	1	theme	composite	1239:1247	arg1	dosage					1255:1260	FeMA composite beads dosage	1234:1260	FeMA composite beads dosage	1234:1260	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	1	2	theme	Fenton	261:266	arg1	process					278:284	the Fenton oxidation process	257:284	the Fenton oxidation process	257:284	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	3	theme	aqueous	1418:1424	arg1	solution					1426:1433	aqueous solution	1418:1433	aqueous solution	1418:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	4	theme	OFL	1411:1413	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	5	theme	different	1311:1319	arg1	oxidants					1321:1328	different oxidants	1311:1328	different oxidants	1311:1328	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	6	theme	photoelectron	681:693	arg1	XPS					709:711	XPS	709:711	XPS	709:711	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	4	6	theme	photoelectron	681:693	arg1	spectroscopy					695:706	X-ray photoelectron spectroscopy	675:706	X-ray photoelectron spectroscopy (XPS)	675:712	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	2	7	theme	alginate	327:334	arg1	beads					353:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	11	8	theme	oxidation	2048:2056	arg1	process					2058:2064	the Fenton oxidation process	2037:2064	the Fenton oxidation process	2037:2064	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	11	9	theme	wastewater	2010:2019	arg1	remediation					2021:2031	wastewater remediation	2010:2031	wastewater remediation	2010:2031	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	1	10	theme	effective	193:201	arg1	catalyst					217:224	an economical, stable, and effective heterogeneous catalyst	166:224	an economical, stable, and effective heterogeneous catalyst for wastewater remediation	166:251	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	11	theme	inorganic	1370:1378	arg1	salts					1380:1384	inorganic salts	1370:1384	inorganic salts on Fenton degradation of OFL in aqueous solution	1370:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	12	dep	Fourier	835:841	arg1	transform					843:851	transform	843:851	transform infrared (FTIR) spectroscopy	843:880	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	9	13	from	entrapment	1629:1638	arg1	beads					1677:1681	alginate beads	1668:1681	alginate beads	1668:1681	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	9	14	theme	iron	1699:1702	arg1	ions					1704:1707	less iron ions	1694:1707	less iron ions leaching compared to previous observation	1694:1749	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	4	15	theme	scanning	730:737	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	5	16	theme	pristine	1042:1049	arg1	beads					1060:1064	pristine alginate beads	1042:1064	pristine alginate beads	1042:1064	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	7	17	from	alginate	1224:1231	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	18	theme	reaction	1344:1351	arg1	temperature					1353:1363	reaction temperature	1344:1363	reaction temperature	1344:1363	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	19	theme	microscope/energy	748:764	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	1	20	theme	study	146:150	arg1	aim					134:136	The primary aim	122:136	The primary aim of this study	122:150	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	21	from	degradation	1396:1406	arg1	solution					1426:1433	aqueous solution	1418:1433	aqueous solution	1418:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	22	theme	FeMA	1234:1237	arg1	dosage					1255:1260	FeMA composite beads dosage	1234:1260	FeMA composite beads dosage	1234:1260	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	11	23	theme	composite	1962:1970	arg1	material					1997:2004	a promising material	1985:2004	a promising material for wastewater remediation	1985:2031	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	11	23	theme	composite	1962:1970	arg1	beads					1972:1976	FeMA composite beads	1957:1976	FeMA composite beads	1957:1976	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	7	24	from	OFL	1411:1413	arg1	solution					1426:1433	aqueous solution	1418:1433	aqueous solution	1418:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	25	theme	field	715:719	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	5	26	theme	FeMA	921:924	arg1	beads					936:940	FeMA composite beads	921:940	FeMA composite beads	921:940	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	8	27	theme	OFL	1497:1499	arg1	degradation					1501:1511	OFL degradation	1497:1511	OFL degradation	1497:1511	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	5	28	theme	higher	963:968	arg1	porosity					991:998	a higher surface area, higher porosity	961:998	a higher surface area, higher porosity	961:998	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	7	29	theme	loading	1213:1219	arg1	effects					1180:1186	The effects	1176:1186	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution	1176:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	30	from	dosage	1336:1341	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	2	31	theme	alginate	423:430	arg1	beads					432:436	calcium alginate beads	415:436	calcium alginate beads	415:436	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	7	32	theme	H2O2	1331:1334	arg1	dosage					1336:1341	H2O2 dosage	1331:1341	H2O2 dosage	1331:1341	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	33	theme	X-ray	777:781	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	0	34	theme	Fenton	0:5	arg1	degradation					7:17	Fenton degradation	0:17	Fenton degradation of ofloxacin	0:30	Fenton degradation of ofloxacin antibiotic using calcium alginate beads impregnated with Fe3O4-montmorillonite composite.					
36586654	1	35	theme	primary	126:132	arg1	aim					134:136	The primary aim	122:136	The primary aim of this study	122:150	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	36	theme	OFL	1292:1294	arg1	concentration					1296:1308	initial OFL concentration	1284:1308	initial OFL concentration	1284:1308	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	3	37	theme	ofloxacin	516:524	arg1	degradation					501:511	the Fenton degradation	490:511	the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies	490:589	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	0	38	theme	calcium	49:55	arg1	beads					66:70	calcium alginate beads	49:70	calcium alginate beads impregnated with Fe3O4-montmorillonite composite	49:119	Fenton degradation of ofloxacin antibiotic using calcium alginate beads impregnated with Fe3O4-montmorillonite composite.					
36586654	7	39	from	concentration	1296:1308	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	6	40	theme	ofloxacin	1136:1144	arg1	degradation					1121:1131	Fenton degradation	1114:1131	Fenton degradation of ofloxacin (OFL)	1114:1150	The composite beads were subsequently used for Fenton degradation of ofloxacin (OFL) in an aqueous solution.					
36586654	8	41	theme	total	1570:1574	arg1	removal					1597:1603	the total organic carbon (TOC) removal	1566:1603	the total organic carbon (TOC) removal	1566:1603	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	7	42	theme	solution	1271:1278	arg1	pH					1280:1281	initial solution pH	1263:1281	initial solution pH	1263:1281	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	8	43	theme	carbon	1584:1589	arg1	removal					1597:1603	the total organic carbon (TOC) removal	1566:1603	the total organic carbon (TOC) removal	1566:1603	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	10	44	theme	degradation	1850:1860	arg1	process					1862:1868	the Fenton degradation process	1839:1868	the Fenton degradation process	1839:1868	The kinetics of the Fenton degradation process are best fitted to the pseudo-first-order kinetic model.					
36586654	5	45	theme	better	1005:1010	arg1	stability					1020:1028	better thermal stability	1005:1028	better thermal stability	1005:1028	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	4	46	theme	FeMA	629:632	arg1	beads					644:648	the FeMA composite beads	625:648	the FeMA composite beads	625:648	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	7	47	theme	beads	1249:1253	arg1	dosage					1255:1260	FeMA composite beads dosage	1234:1260	FeMA composite beads dosage	1234:1260	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	11	48	theme	promising	1987:1995	arg1	material					1997:2004	a promising material	1985:2004	a promising material for wastewater remediation	1985:2031	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	11	48	theme	promising	1987:1995	arg1	beads					1972:1976	FeMA composite beads	1957:1976	FeMA composite beads	1957:1976	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	1	49	theme	oxidation	268:276	arg1	process					278:284	the Fenton oxidation process	257:284	the Fenton oxidation process	257:284	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	50	from	dosage	1255:1260	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	51	theme	physiochemical	596:609	arg1	properties					611:620	The physiochemical properties	592:620	The physiochemical properties of the FeMA composite beads	592:648	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	1	52	theme	economical	169:178	arg1	catalyst					217:224	an economical, stable, and effective heterogeneous catalyst	166:224	an economical, stable, and effective heterogeneous catalyst for wastewater remediation	166:251	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	9	53	theme	Fe3O4-montmorillonite	1643:1663	arg1	entrapment					1629:1638	The entrapment	1625:1638	The entrapment of Fe3O4-montmorillonite in alginate beads	1625:1681	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	6	54	theme	aqueous	1158:1164	arg1	solution					1166:1173	an aqueous solution	1155:1173	an aqueous solution	1155:1173	The composite beads were subsequently used for Fenton degradation of ofloxacin (OFL) in an aqueous solution.					
36586654	4	55	theme	X-ray	675:679	arg1	XPS					709:711	XPS	709:711	XPS	709:711	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	4	55	theme	X-ray	675:679	arg1	spectroscopy					695:706	X-ray photoelectron spectroscopy	675:706	X-ray photoelectron spectroscopy (XPS)	675:712	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	10	56	theme	kinetic	1912:1918	arg1	model					1920:1924	the pseudo-first-order kinetic model	1889:1924	the pseudo-first-order kinetic model	1889:1924	The kinetics of the Fenton degradation process are best fitted to the pseudo-first-order kinetic model.					
36586654	3	57	theme	water	578:582	arg1	bodies					584:589	water bodies	578:589	water bodies	578:589	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	3	58	located	detected	566:573	arg2	antibiotic					536:545	antibiotic	536:545	antibiotic	536:545	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	3	58	located	detected	566:573	arg2	ofloxacin					516:524	ofloxacin	516:524	ofloxacin (OFL)	516:530	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	3	58	located	detected	566:573	arg1	bodies					584:589	water bodies	578:589	water bodies	578:589	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	1	59	theme	stable	181:186	arg1	catalyst					217:224	an economical, stable, and effective heterogeneous catalyst	166:224	an economical, stable, and effective heterogeneous catalyst for wastewater remediation	166:251	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	9	60	theme	alginate	1668:1675	arg1	beads					1677:1681	alginate beads	1668:1681	alginate beads	1668:1681	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	7	61	from	pH	1280:1281	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	2	62	theme	Fe3O4-montmorillonite	305:325	arg1	beads					353:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	7	63	from	effects	1180:1186	arg1	oxidants					1321:1328	different oxidants	1311:1328	different oxidants	1311:1328	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	dosage					1255:1260	FeMA composite beads dosage	1234:1260	FeMA composite beads dosage	1234:1260	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	salts					1380:1384	inorganic salts	1370:1384	inorganic salts on Fenton degradation of OFL in aqueous solution	1370:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	concentration					1296:1308	initial OFL concentration	1284:1308	initial OFL concentration	1284:1308	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	alginate					1224:1231	alginate	1224:1231	alginate	1224:1231	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	dosage					1336:1341	H2O2 dosage	1331:1341	H2O2 dosage	1331:1341	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	temperature					1353:1363	reaction temperature	1344:1363	reaction temperature	1344:1363	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	63	from	effects	1180:1186	arg1	pH					1280:1281	initial solution pH	1263:1281	initial solution pH	1263:1281	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	64	theme	Fenton	1389:1394	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	5	65	contain	have	956:959	arg1	beads					936:940	FeMA composite beads	921:940	FeMA composite beads	921:940	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	5	65	contain	have	956:959	arg2	porosity					991:998	a higher surface area, higher porosity	961:998	a higher surface area, higher porosity	961:998	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	4	66	theme	beads	644:648	arg1	properties					611:620	The physiochemical properties	592:620	The physiochemical properties of the FeMA composite beads	592:648	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	1	67	theme	heterogeneous	203:215	arg1	catalyst					217:224	an economical, stable, and effective heterogeneous catalyst	166:224	an economical, stable, and effective heterogeneous catalyst for wastewater remediation	166:251	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	11	68	theme	Fenton	2041:2046	arg1	process					2058:2064	the Fenton oxidation process	2037:2064	the Fenton oxidation process	2037:2064	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	6	69	used	used	1105:1108	arg2	beads					1081:1085	The composite beads	1067:1085	The composite beads	1067:1085	The composite beads were subsequently used for Fenton degradation of ofloxacin (OFL) in an aqueous solution.					
36586654	5	70	theme	composite	926:934	arg1	beads					936:940	FeMA composite beads	921:940	FeMA composite beads	921:940	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	9	71	theme	ions	1704:1707	arg1	leaching					1709:1716	less iron ions leaching	1694:1716	less iron ions leaching compared to previous observation	1694:1749	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	4	72	theme	emission	721:728	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	5	73	theme	alginate	1051:1058	arg1	beads					1060:1064	pristine alginate beads	1042:1064	pristine alginate beads	1042:1064	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	4	74	theme	electron	739:746	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	11	75	theme	FeMA	1957:1960	arg1	material					1997:2004	a promising material	1985:2004	a promising material for wastewater remediation	1985:2031	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	11	75	theme	FeMA	1957:1960	arg1	beads					1972:1976	FeMA composite beads	1957:1976	FeMA composite beads	1957:1976	It is therefore believed that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.					
36586654	9	76	theme	previous	1730:1737	arg1	observation					1739:1749	previous observation	1730:1749	previous observation	1730:1749	The entrapment of Fe3O4-montmorillonite in alginate beads results in less iron ions leaching compared to previous observation, and the efficiency remains constant over the five cycles investigated.					
36586654	5	77	dep	higher	963:968	arg1	area					978:981	surface area	970:981	surface area	970:981	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	5	77	dep	higher	963:968	arg1	higher					984:989	higher	984:989	higher	984:989	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	0	78	theme	Fe3O4-montmorillonite	89:109	arg1	composite					111:119	Fe3O4-montmorillonite composite	89:119	Fe3O4-montmorillonite composite	89:119	Fenton degradation of ofloxacin antibiotic using calcium alginate beads impregnated with Fe3O4-montmorillonite composite.					
36586654	8	79	theme	degradation	1501:1511	arg1	percentage					1483:1492	the percentage	1479:1492	the percentage of OFL degradation	1479:1511	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	7	80	theme	Fe3O4-montmorillonite	1191:1211	arg1	loading					1213:1219	Fe3O4-montmorillonite loading	1191:1219	Fe3O4-montmorillonite loading	1191:1219	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	5	81	theme	surface	970:976	arg1	area					978:981	surface area	970:981	surface area	970:981	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	7	82	from	solution	1426:1433	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	4	83	dep	infrared	853:860	arg1	FTIR					863:866	FTIR	863:866	FTIR	863:866	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	4	84	theme	Brunauer-Emmett-Teller	796:817	arg1	analysis					825:832	Brunauer-Emmett-Teller (BET) analysis	796:832	Brunauer-Emmett-Teller (BET) analysis	796:832	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	2	85	theme	calcium	415:421	arg1	beads					432:436	calcium alginate beads	415:436	calcium alginate beads	415:436	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	7	86	from	temperature	1353:1363	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	6	87	theme	composite	1071:1079	arg1	beads					1081:1085	The composite beads	1067:1085	The composite beads	1067:1085	The composite beads were subsequently used for Fenton degradation of ofloxacin (OFL) in an aqueous solution.					
36586654	8	88	theme	optimized	1538:1546	arg1	conditions					1548:1557	optimized conditions	1538:1557	optimized conditions	1538:1557	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	4	89	theme	dispersive	766:775	arg1	FESEM/EDX					784:792	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX)	715:793	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	0	90	theme	ofloxacin	22:30	arg1	degradation					7:17	Fenton degradation	0:17	Fenton degradation of ofloxacin	0:30	Fenton degradation of ofloxacin antibiotic using calcium alginate beads impregnated with Fe3O4-montmorillonite composite.					
36586654	10	91	theme	Fenton	1843:1848	arg1	process					1862:1868	the Fenton degradation process	1839:1868	the Fenton degradation process	1839:1868	The kinetics of the Fenton degradation process are best fitted to the pseudo-first-order kinetic model.					
36586654	3	92	theme	Fenton	494:499	arg1	degradation					501:511	the Fenton degradation	490:511	the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies	490:589	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	5	93	theme	thermal	1012:1018	arg1	stability					1020:1028	better thermal stability	1005:1028	better thermal stability	1005:1028	FeMA composite beads were found to have a higher surface area, higher porosity, and better thermal stability compared to pristine alginate beads.					
36586654	7	94	from	salts	1380:1384	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	7	95	theme	initial	1284:1290	arg1	concentration					1296:1308	initial OFL concentration	1284:1308	initial OFL concentration	1284:1308	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	3	96	theme	catalysts	462:470	arg1	performance					443:453	The performance	439:453	The performance of the catalysts	439:470	The performance of the catalysts was evaluated via the Fenton degradation of ofloxacin (OFL), an antibiotic that is frequently detected in water bodies.					
36586654	0	97	theme	alginate	57:64	arg1	beads					66:70	calcium alginate beads	49:70	calcium alginate beads impregnated with Fe3O4-montmorillonite composite	49:119	Fenton degradation of ofloxacin antibiotic using calcium alginate beads impregnated with Fe3O4-montmorillonite composite.					
36586654	8	98	theme	organic	1576:1582	arg1	removal					1597:1603	the total organic carbon (TOC) removal	1566:1603	the total organic carbon (TOC) removal	1566:1603	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36586654	4	99	theme	infrared	853:860	arg1	spectroscopy					869:880	infrared (FTIR) spectroscopy	853:880	infrared (FTIR) spectroscopy	853:880	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	2	100	theme	composite	343:351	arg1	beads					353:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	7	101	theme	initial	1263:1269	arg1	pH					1280:1281	initial solution pH	1263:1281	initial solution pH	1263:1281	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	10	102	theme	process	1862:1868	arg1	kinetics					1827:1834	The kinetics	1823:1834	The kinetics of the Fenton degradation process	1823:1868	The kinetics of the Fenton degradation process are best fitted to the pseudo-first-order kinetic model.					
36586654	4	103	theme	BET	820:822	arg1	analysis					825:832	Brunauer-Emmett-Teller (BET) analysis	796:832	Brunauer-Emmett-Teller (BET) analysis	796:832	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	2	104	theme	FeMA	337:340	arg1	beads					353:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	Fe3O4-montmorillonite alginate (FeMA) composite beads	305:357	For this purpose, Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized by entrapping Fe3O4-montmorillonite in calcium alginate beads.					
36586654	1	105	theme	wastewater	230:239	arg1	remediation					241:251	wastewater remediation	230:251	wastewater remediation	230:251	The primary aim of this study is to develop an economical, stable, and effective heterogeneous catalyst for wastewater remediation via the Fenton oxidation process.					
36586654	7	106	from	oxidants	1321:1328	arg1	degradation					1396:1406	Fenton degradation	1389:1406	Fenton degradation of OFL in aqueous solution	1389:1433	The effects of Fe3O4-montmorillonite loading on alginate, FeMA composite beads dosage, initial solution pH, initial OFL concentration, different oxidants, H2O2 dosage, reaction temperature, and inorganic salts on Fenton degradation of OFL in aqueous solution was investigated.					
36586654	6	107	theme	Fenton	1114:1119	arg1	degradation					1121:1131	Fenton degradation	1114:1131	Fenton degradation of ofloxacin (OFL)	1114:1150	The composite beads were subsequently used for Fenton degradation of ofloxacin (OFL) in an aqueous solution.					
36586654	4	108	theme	composite	634:642	arg1	beads					644:648	the FeMA composite beads	625:648	the FeMA composite beads	625:648	The physiochemical properties of the FeMA composite beads were characterized using X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA).					
36586654	10	109	theme	pseudo-first-order	1893:1910	arg1	model					1920:1924	the pseudo-first-order kinetic model	1889:1924	the pseudo-first-order kinetic model	1889:1924	The kinetics of the Fenton degradation process are best fitted to the pseudo-first-order kinetic model.					
36586654	8	110	theme	TOC	1592:1594	arg1	removal					1597:1603	the total organic carbon (TOC) removal	1566:1603	the total organic carbon (TOC) removal	1566:1603	The results revealed that the percentage of OFL degradation reached about 80 % under optimized conditions, while the total organic carbon (TOC) removal reached about 53 %.					
36241325	3	0	theme	dual	299:302	arg1	method					326:331	an improved dual ice-template assembly method	287:331	an improved dual ice-template assembly method	287:331	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	1	from	removal	521:527	arg1	water					541:545	water	541:545	water	541:545	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	2	theme	ice-template	304:315	arg1	method					326:331	an improved dual ice-template assembly method	287:331	an improved dual ice-template assembly method	287:331	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	1	3	from	persistence	153:163	arg1	environment					172:182	the environment	168:182	the environment	168:182	Pharmaceuticals and personal care products (PPCPs) are gaining attention due to their persistence in the environment.					
36241325	3	4	from	PPCPs	532:536	arg1	water					541:545	water	541:545	water	541:545	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	5	theme	first	568:572	arg1	time					574:577	the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water	564:822	the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water	564:822	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	3	6	theme	PPCPs	532:536	arg1	removal					521:527	removal	521:527	removal	521:527	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	6	theme	PPCPs	532:536	arg1	adsorption					506:515	adsorption	506:515	adsorption	506:515	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	7	from	adsorption	506:515	arg1	water					541:545	water	541:545	water	541:545	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	8	theme	viable	763:768	arg1	option					770:775	a viable option	761:775	a viable option for long-lasting adsorbents for PPCPs in water	761:822	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	8	theme	viable	763:768	arg1	which					746:750	which	746:750	which	746:750	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	9	theme	bacterial	632:640	arg1	filtration					642:651	bacterial filtration	632:651	bacterial filtration	632:651	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	1	10	theme	personal	87:94	arg1	products					101:108	personal care products	87:108	personal care products (PPCPs)	87:116	Pharmaceuticals and personal care products (PPCPs) are gaining attention due to their persistence in the environment.					
36241325	1	10	theme	personal	87:94	arg1	PPCPs					111:115	PPCPs	111:115	PPCPs	111:115	Pharmaceuticals and personal care products (PPCPs) are gaining attention due to their persistence in the environment.					
36241325	0	11	theme	multifunctional	2:16	arg1	aerogel					37:43	A multifunctional chitosan composite aerogel	0:43	A multifunctional chitosan composite aerogel for PPCPs adsorption.	0:65	A multifunctional chitosan composite aerogel for PPCPs adsorption.					
36241325	1	12	theme	care	96:99	arg1	products					101:108	personal care products	87:108	personal care products (PPCPs)	87:116	Pharmaceuticals and personal care products (PPCPs) are gaining attention due to their persistence in the environment.					
36241325	1	12	theme	care	96:99	arg1	PPCPs					111:115	PPCPs	111:115	PPCPs	111:115	Pharmaceuticals and personal care products (PPCPs) are gaining attention due to their persistence in the environment.					
36241325	3	13	theme	benzoquinone-modified	411:431	arg1	oxide					442:446	benzoquinone-modified graphene oxide	411:446	benzoquinone-modified graphene oxide (QGO)	411:452	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	13	theme	benzoquinone-modified	411:431	arg1	QGO					449:451	QGO	449:451	QGO	449:451	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	14	theme	ZIF-67/QGO/SB-CS	370:385	arg1	aerogel					387:393	ZIF-67/QGO/SB-CS aerogel	370:393	ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS)	370:496	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	15	used	used	342:345	arg2	method					326:331	an improved dual ice-template assembly method	287:331	an improved dual ice-template assembly method	287:331	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	16	theme	graphene	433:440	arg1	oxide					442:446	benzoquinone-modified graphene oxide	411:446	benzoquinone-modified graphene oxide (QGO)	411:452	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	16	theme	graphene	433:440	arg1	QGO					449:451	QGO	449:451	QGO	449:451	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	0	17	theme	composite	27:35	arg1	aerogel					37:43	A multifunctional chitosan composite aerogel	0:43	A multifunctional chitosan composite aerogel for PPCPs adsorption.	0:65	A multifunctional chitosan composite aerogel for PPCPs adsorption.					
36241325	0	18	theme	chitosan	18:25	arg1	aerogel					37:43	A multifunctional chitosan composite aerogel	0:43	A multifunctional chitosan composite aerogel for PPCPs adsorption.	0:65	A multifunctional chitosan composite aerogel for PPCPs adsorption.					
36241325	4	19	contain	has	615:617	arg2	filtration					642:651	bacterial filtration	632:651	bacterial filtration	632:651	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	19	contain	has	615:617	arg2	antifouling					619:629	antifouling	619:629	antifouling	619:629	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	19	contain	has	615:617	arg1	aerogel					607:613	the chitosan composite aerogel	584:613	the chitosan composite aerogel	584:613	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	19	contain	has	615:617	arg2	separation					667:676	oil-water separation	657:676	oil-water separation	657:676	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	3	20	dep	adsorption	506:515	arg1	the					502:504	the	502:504	the	502:504	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	21	theme	composite	597:605	arg1	aerogel					607:613	the chitosan composite aerogel	584:613	the chitosan composite aerogel	584:613	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	22	dep	antifouling	619:629	arg1	abilities					678:686	abilities	678:686	abilities	678:686	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	2	23	theme	adsorbents	221:230	arg1	development					200:210	the development	196:210	the development of novel adsorbents to remove them	196:245	Therefore, the development of novel adsorbents to remove them is strongly anticipated.					
36241325	3	24	theme	aerogel	387:393	arg1	preparation					355:365	the preparation	351:365	the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS)	351:496	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	2	25	theme	novel	215:219	arg1	adsorbents					221:230	novel adsorbents	215:230	novel adsorbents	215:230	Therefore, the development of novel adsorbents to remove them is strongly anticipated.					
36241325	4	26	theme	PPCPs	703:707	arg1	performance					720:730	excellent PPCPs adsorption performance	693:730	excellent PPCPs adsorption performance	693:730	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	0	27	theme	PPCPs	49:53	arg1	adsorption					55:64	PPCPs adsorption	49:64	PPCPs adsorption	49:64	A multifunctional chitosan composite aerogel for PPCPs adsorption.					
36241325	3	28	theme	improved	290:297	arg1	method					326:331	an improved dual ice-template assembly method	287:331	an improved dual ice-template assembly method	287:331	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	29	from	PPCPs	809:813	arg1	water					818:822	water	818:822	water	818:822	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	30	theme	excellent	693:701	arg1	performance					720:730	excellent PPCPs adsorption performance	693:730	excellent PPCPs adsorption performance	693:730	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	31	dep	has	615:617	arg1	option					770:775	a viable option	761:775	a viable option for long-lasting adsorbents for PPCPs in water	761:822	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	31	dep	has	615:617	arg1	which					746:750	which	746:750	which	746:750	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	3	32	theme	sulfobetaine-modified	459:479	arg1	SB-CS					491:495	SB-CS	491:495	SB-CS	491:495	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	32	theme	sulfobetaine-modified	459:479	arg1	chitosan					481:488	sulfobetaine-modified chitosan	459:488	sulfobetaine-modified chitosan (SB-CS)	459:496	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	33	from	water	541:545	arg1	removal					521:527	removal	521:527	removal	521:527	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	3	33	from	water	541:545	arg1	adsorption					506:515	adsorption	506:515	adsorption	506:515	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	34	theme	adsorption	709:718	arg1	performance					720:730	excellent PPCPs adsorption performance	693:730	excellent PPCPs adsorption performance	693:730	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	3	35	theme	assembly	317:324	arg1	method					326:331	an improved dual ice-template assembly method	287:331	an improved dual ice-template assembly method	287:331	In this study, an improved dual ice-template assembly method had been used for the preparation of ZIF-67/QGO/SB-CS aerogel through ZIF-67, benzoquinone-modified graphene oxide (QGO), and sulfobetaine-modified chitosan (SB-CS) for the adsorption and removal of PPCPs in water.					
36241325	4	36	theme	chitosan	588:595	arg1	aerogel					607:613	the chitosan composite aerogel	584:613	the chitosan composite aerogel	584:613	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	37	theme	long-lasting	781:792	arg1	adsorbents					794:803	long-lasting adsorbents	781:803	long-lasting adsorbents	781:803	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
36241325	4	38	theme	oil-water	657:665	arg1	separation					667:676	oil-water separation	657:676	oil-water separation	657:676	We reported for the first time that the chitosan composite aerogel has antifouling, bacterial filtration and oil-water separation abilities with excellent PPCPs adsorption performance and reusable, which would be a viable option for long-lasting adsorbents for PPCPs in water.					
35451187	4	0	theme	coordination	913:924	arg1	bonds					926:930	iron-catechol coordination bonds	899:930	iron-catechol coordination bonds	899:930	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	7	1	theme	inherent	1457:1464	arg1	activity					1480:1487	inherent antimicrobial activity	1457:1487	inherent antimicrobial activity	1457:1487	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	0	2	theme	Photothermal	103:114	arg1	Activity					116:123	Photothermal Activity	103:123	Photothermal Activity	103:123	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	6	3	theme	in	1115:1116	arg1	experiments					1123:1133	The in vitro and in vivo experiments	1098:1133	The in vitro and in vivo experiments	1098:1133	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	0	4	theme	Infected	129:136	arg1	Healing					144:150	Infected Wound Healing	129:150	Infected Wound Healing	129:150	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	7	5	theme	remarkable	1387:1396	arg1	potential					1398:1406	remarkable potential	1387:1406	remarkable potential for bacteria-infected wound healing	1387:1442	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	2	6	theme	wound	313:317	arg1	dressing					319:326	wound dressing	313:326	wound dressing	313:326	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	4	7	with	bonds	853:857	arg1	AHA					890:892	AHA	890:892	AHA	890:892	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	4	7	with	bonds	853:857	arg1	acid					884:887	aldehyde hyaluronic acid	864:887	aldehyde hyaluronic acid (AHA)	864:893	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	7	8	theme	antioxidant	1490:1500	arg1	capability					1502:1511	antioxidant capability	1490:1511	antioxidant capability	1490:1511	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	5	9	theme	Fe3+	985:988	arg1	presence					973:980	The presence	969:980	The presence of Fe3+	969:988	The presence of Fe3+ can also promote covalent polymerization of dopamine, which endows the hydrogel with photothermal capacity.					
35451187	0	10	theme	Self-Adhesive	0:12	arg1	Hydrogel					62:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel	0:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.	0:151	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	7	11	theme	wound	1430:1434	arg1	healing					1436:1442	bacteria-infected wound healing	1412:1442	bacteria-infected wound healing	1412:1442	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	3	12	theme	bacteria-infected	747:763	arg1	wounds					765:770	bacteria-infected wounds	747:770	bacteria-infected wounds	747:770	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	3	13	theme	-based	536:541	arg1	hydrogel					553:560	a hyaluronic acid (HA)-based composite hydrogel	514:560	a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions	514:645	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	6	14	theme	in	1102:1103	arg1	experiments					1123:1133	The in vitro and in vivo experiments	1098:1133	The in vitro and in vivo experiments	1098:1133	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	0	15	theme	Wound	138:142	arg1	Healing					144:150	Infected Wound Healing	129:150	Infected Wound Healing	129:150	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	3	16	theme	healing	728:734	arg1	process					736:742	healing process	728:742	healing process of bacteria-infected wounds	728:770	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	2	17	theme	composite	290:298	arg1	hydrogels					300:308	many composite hydrogels	285:308	many composite hydrogels as wound dressing	285:326	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	0	18	theme	Hyaluronic	14:23	arg1	Hydrogel					62:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel	0:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.	0:151	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	3	19	theme	process	736:742	arg1	acceleration					712:723	acceleration	712:723	acceleration of healing process of bacteria-infected wounds	712:770	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	3	19	theme	process	736:742	arg1	promotion					698:706	photothermal-assisted promotion	676:706	photothermal-assisted promotion	676:706	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	4	20	theme	hyaluronic	873:882	arg1	AHA					890:892	AHA	890:892	AHA	890:892	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	4	20	theme	hyaluronic	873:882	arg1	acid					884:887	aldehyde hyaluronic acid	864:887	aldehyde hyaluronic acid (AHA)	864:893	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	3	21	theme	dopamine-substituted	578:597	arg1	DAP					622:624	DAP	622:624	DAP	622:624	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	3	21	theme	dopamine-substituted	578:597	arg1	peptide					613:619	a dopamine-substituted antimicrobial peptide	576:619	a dopamine-substituted antimicrobial peptide (DAP)	576:625	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	2	22	theme	infected	476:483	arg1	healing					491:497	the infected wound healing	472:497	the infected wound healing	472:497	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	7	23	theme	photothermal	1518:1529	arg1	effect					1531:1536	photothermal effect	1518:1536	photothermal effect	1518:1536	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	4	24	theme	aldehyde	864:871	arg1	AHA					890:892	AHA	890:892	AHA	890:892	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	4	24	theme	aldehyde	864:871	arg1	acid					884:887	aldehyde hyaluronic acid	864:887	aldehyde hyaluronic acid (AHA)	864:893	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	3	25	theme	antimicrobial	599:611	arg1	DAP					622:624	DAP	622:624	DAP	622:624	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	3	25	theme	antimicrobial	599:611	arg1	peptide					613:619	a dopamine-substituted antimicrobial peptide	576:619	a dopamine-substituted antimicrobial peptide (DAP)	576:625	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	4	26	with	bonds	926:930	arg1	AHA					890:892	AHA	890:892	AHA	890:892	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	4	26	with	bonds	926:930	arg1	acid					884:887	aldehyde hyaluronic acid	864:887	aldehyde hyaluronic acid (AHA)	864:893	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	2	27	theme	photothermal	389:400	arg1	hydrogels					402:410	photothermal hydrogels	389:410	photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing	389:497	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	0	28	theme	Peptide	44:50	arg1	Hydrogel					62:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel	0:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.	0:151	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	7	29	theme	bacteria-infected	1412:1428	arg1	healing					1436:1442	bacteria-infected wound healing	1412:1442	bacteria-infected wound healing	1412:1442	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	6	30	dep	in	1102:1103	arg1	vitro					1105:1109	vitro	1105:1109	vitro	1105:1109	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	6	31	theme	collagen	1269:1276	arg1	deposition					1278:1287	accelerated collagen deposition	1257:1287	accelerated collagen deposition	1257:1287	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	7	32	theme	multifunctional	1342:1356	arg1	hydrogel					1368:1375	the multifunctional composite hydrogel	1338:1375	the multifunctional composite hydrogel	1338:1375	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	0	33	theme	Acid/Antimicrobial	25:42	arg1	Hydrogel					62:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel	0:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.	0:151	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	3	34	theme	wounds	765:770	arg1	process					736:742	healing process	728:742	healing process of bacteria-infected wounds	728:770	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	4	35	theme	antimicrobial	794:806	arg1	agent					808:812	antimicrobial agent	794:812	antimicrobial agent	794:812	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	6	36	theme	wound	1209:1213	arg1	healing					1215:1221	the infected wound healing	1196:1221	the infected wound healing process	1196:1229	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	6	37	theme	composite	1150:1158	arg1	hydrogel					1160:1167	the composite hydrogel	1146:1167	the composite hydrogel	1146:1167	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	7	38	theme	composite	1358:1366	arg1	hydrogel					1368:1375	the multifunctional composite hydrogel	1338:1375	the multifunctional composite hydrogel	1338:1375	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	3	39	theme	hyaluronic	516:525	arg1	acid					527:530	hyaluronic acid	516:530	hyaluronic acid	516:530	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	4	40	theme	composite	949:957	arg1	hydrogel					959:966	the composite hydrogel	945:966	the composite hydrogel	945:966	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	5	41	theme	dopamine	1034:1041	arg1	polymerization					1016:1029	covalent polymerization	1007:1029	covalent polymerization	1007:1029	The presence of Fe3+ can also promote covalent polymerization of dopamine, which endows the hydrogel with photothermal capacity.					
35451187	0	42	theme	Composite	52:60	arg1	Hydrogel					62:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel	0:69	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.	0:151	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	6	43	theme	accelerated	1257:1267	arg1	deposition					1278:1287	accelerated collagen deposition	1257:1287	accelerated collagen deposition	1257:1287	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	0	44	theme	Antioxidant	76:86	arg1	Capability					88:97	Antioxidant Capability	76:97	Antioxidant Capability	76:97	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	4	45	theme	iron-catechol	899:911	arg1	bonds					926:930	iron-catechol coordination bonds	899:930	iron-catechol coordination bonds	899:930	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	4	46	theme	base	848:851	arg1	bonds					853:857	Schiff's base bonds	839:857	Schiff's base bonds with aldehyde hyaluronic acid (AHA)	839:893	DAP, serving as both antimicrobial agent and ROS-scavenger, forms Schiff's base bonds with aldehyde hyaluronic acid (AHA) and iron-catechol coordination bonds to reinforce the composite hydrogel.					
35451187	3	47	dep	-based	536:541	arg1	acid					527:530	hyaluronic acid	516:530	hyaluronic acid	516:530	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	6	48	theme	infected	1200:1207	arg1	healing					1215:1221	the infected wound healing	1196:1221	the infected wound healing process	1196:1229	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	7	49	contain	possesses	1377:1385	arg2	potential					1398:1406	remarkable potential	1387:1406	remarkable potential for bacteria-infected wound healing	1387:1442	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	7	49	contain	possesses	1377:1385	arg1	hydrogel					1368:1375	the multifunctional composite hydrogel	1338:1375	the multifunctional composite hydrogel	1338:1375	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	6	50	dep	in	1115:1116	arg1	vivo					1118:1121	vivo	1118:1121	vivo	1118:1121	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	1	51	theme	Bacterial	153:161	arg1	infection					163:171	Bacterial infection	153:171	Bacterial infection	153:171	Bacterial infection can delay wound healing, causing wounds to deteriorate and even threaten the patient's life.					
35451187	6	52	theme	healing	1215:1221	arg1	process					1223:1229	the infected wound healing process	1196:1229	the infected wound healing process	1196:1229	The in vitro and in vivo experiments prove that the composite hydrogel can effectively accelerate the infected wound healing process, including antibacterial, accelerated collagen deposition, and re-epithelization.					
35451187	3	53	theme	photothermal-assisted	676:696	arg1	promotion					698:706	photothermal-assisted promotion	676:706	photothermal-assisted promotion	676:706	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	2	54	theme	many	285:288	arg1	hydrogels					300:308	many composite hydrogels	285:308	many composite hydrogels as wound dressing	285:326	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	7	55	theme	antimicrobial	1466:1478	arg1	activity					1480:1487	inherent antimicrobial activity	1457:1487	inherent antimicrobial activity	1457:1487	This study suggests that the multifunctional composite hydrogel possesses remarkable potential for bacteria-infected wound healing by combining inherent antimicrobial activity, antioxidant capability, and photothermal effect.					
35451187	3	56	theme	composite	543:551	arg1	hydrogel					553:560	a hyaluronic acid (HA)-based composite hydrogel	514:560	a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions	514:645	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	5	57	theme	covalent	1007:1014	arg1	polymerization					1016:1029	covalent polymerization	1007:1029	covalent polymerization	1007:1029	The presence of Fe3+ can also promote covalent polymerization of dopamine, which endows the hydrogel with photothermal capacity.					
35451187	1	58	theme	wound	183:187	arg1	healing					189:195	wound healing	183:195	wound healing	183:195	Bacterial infection can delay wound healing, causing wounds to deteriorate and even threaten the patient's life.					
35451187	5	59	theme	photothermal	1075:1086	arg1	capacity					1088:1095	photothermal capacity	1075:1095	photothermal capacity	1075:1095	The presence of Fe3+ can also promote covalent polymerization of dopamine, which endows the hydrogel with photothermal capacity.					
35451187	2	60	dep	antimicrobial	417:429	arg1	properties					447:456	properties	447:456	properties	447:456	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	2	61	with	hydrogels	402:410	arg1	antioxidant					435:445	antioxidant	435:445	antioxidant	435:445	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	2	61	with	hydrogels	402:410	arg1	antimicrobial					417:429	antimicrobial	417:429	antimicrobial	417:429	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
35451187	3	62	theme	Iron	631:634	arg1	ions					642:645	Iron (III) ions	631:645	Iron (III) ions	631:645	In this work, a hyaluronic acid (HA)-based composite hydrogel consisting of a dopamine-substituted antimicrobial peptide (DAP) and Iron (III) ions is developed, which exhibits photothermal-assisted promotion and acceleration of healing process of bacteria-infected wounds.					
35451187	0	63	with	Hydrogel	62:69	arg1	Capability					88:97	Antioxidant Capability	76:97	Antioxidant Capability	76:97	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	0	63	with	Hydrogel	62:69	arg1	Activity					116:123	Photothermal Activity	103:123	Photothermal Activity	103:123	Self-Adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.					
35451187	2	64	theme	wound	485:489	arg1	healing					491:497	the infected wound healing	472:497	the infected wound healing	472:497	Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal hydrogels with antimicrobial and antioxidant properties to accelerate the infected wound healing.					
37254345	9	0	theme	potential	1485:1493	arg1	mechanisms					1495:1504	the potential mechanisms	1481:1504	the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods	1481:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	6	1	theme	cellular	1151:1158	arg1	structure					1160:1168	its less damaged cellular structure	1134:1168	its less damaged cellular structure	1134:1168	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	3	2	theme	processing	466:475	arg1	methods					477:483	The processing methods	462:483	The processing methods applied	462:491	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	2	theme	processing	466:475	arg1	flaking-boiling					498:512	flaking-boiling	498:512	flaking-boiling	498:512	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	2	theme	processing	466:475	arg1	flake					518:522	HB flake	515:522	HB flake	515:522	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	3	theme	HB	515:516	arg1	methods					477:483	The processing methods	462:483	The processing methods applied	462:491	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	3	theme	HB	515:516	arg1	flaking-boiling					498:512	flaking-boiling	498:512	flaking-boiling	498:512	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	3	theme	HB	515:516	arg1	flake					518:522	HB flake	515:522	HB flake	515:522	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	9	4	theme	cell	1513:1516	arg1	integrity					1523:1531	cell wall integrity	1513:1531	cell wall integrity	1513:1531	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	7	5	theme	fatty	1268:1272	arg1	acids					1274:1278	total short-chain fatty acids	1250:1278	total short-chain fatty acids	1250:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	4	6	theme	Puffed	604:609	arg1	HB					611:612	Puffed HB	604:612	Puffed HB	604:612	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	7	7	theme	HB	1296:1297	arg1	flake					1299:1303	HB flake	1296:1303	HB flake	1296:1303	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	7	8	theme	total	1250:1254	arg1	acids					1274:1278	total short-chain fatty acids	1250:1278	total short-chain fatty acids	1250:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	6	9	theme	β-glucan	1118:1125	arg1	digestibility					1080:1092	the lowest starch digestibility	1062:1092	the lowest starch digestibility	1062:1092	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	6	9	theme	β-glucan	1118:1125	arg1	β-glucan					1118:1125	β-glucan	1118:1125	β-glucan	1118:1125	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	6	9	theme	β-glucan	1118:1125	arg1	amount					1108:1113	the least amount	1098:1113	the least amount of β-glucan due to its less damaged cellular structure	1098:1168	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	2	10	from	effects	325:331	arg1	barley					377:382	highland barley	368:382	highland barley	368:382	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	10	from	effects	325:331	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	10	from	effects	325:331	arg1	one					385:387	one	385:387	one	385:387	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	6	11	theme	gastroduodenal	1016:1029	arg1	digestion					1031:1039	in vitro gastroduodenal digestion	1007:1039	in vitro gastroduodenal digestion	1007:1039	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	5	12	theme	emptying	773:780	arg1	half-time					752:760	The half-time	748:760	The half-time of gastric emptying (t1/2)	748:787	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	5	12	theme	emptying	773:780	arg1	slowest					797:803	the slowest	793:803	the slowest for Tsamba (132.3 min)	793:826	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	7	13	theme	in	1227:1228	arg1	production					1236:1245	a 21% and 18% higher in vitro production	1206:1245	a 21% and 18% higher in vitro production of total short-chain fatty acids	1206:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	0	14	theme	highland	126:133	arg1	foods					142:146	highland barley foods	126:146	highland barley foods	126:146	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	9	15	theme	in	1564:1565	arg1	digestibility					1580:1592	in vitro starch digestibility	1564:1592	in vitro starch digestibility	1564:1592	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	6	16	theme	least	1102:1106	arg1	β-glucan					1118:1125	β-glucan	1118:1125	β-glucan	1118:1125	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	6	16	theme	least	1102:1106	arg1	amount					1108:1113	the least amount	1098:1113	the least amount of β-glucan due to its less damaged cellular structure	1098:1168	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	4	17	theme	damaged	646:652	arg1	content					661:667	damaged starch content	646:667	damaged starch content	646:667	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	0	18	theme	foods	142:146	arg1	digestibility					80:92	starch digestibility	73:92	starch digestibility	73:92	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	0	18	theme	foods	142:146	arg1	emptying					51:58	gastric emptying	43:58	gastric emptying	43:58	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	0	18	theme	foods	142:146	arg1	performance					111:121	fermentation performance	98:121	fermentation performance	98:121	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	8	19	dep	in	1408:1409	arg1	vitro					1411:1415	vitro	1411:1415	vitro	1411:1415	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	3	20	theme	Puffed	541:546	arg1	HB					548:549	Puffed HB	541:549	Puffed HB	541:549	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	21	dep	flaking-boiling	498:512	arg1	methods					477:483	The processing methods	462:483	The processing methods applied	462:491	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	21	dep	flaking-boiling	498:512	arg1	flaking-boiling					498:512	flaking-boiling	498:512	flaking-boiling	498:512	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	3	21	dep	flaking-boiling	498:512	arg1	flake					518:522	HB flake	515:522	HB flake	515:522	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	9	22	theme	starch	1573:1578	arg1	digestibility					1580:1592	in vitro starch digestibility	1564:1592	in vitro starch digestibility	1564:1592	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	4	23	theme	content	661:667	arg1	levels					636:641	higher levels	629:641	higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity	629:731	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	5	24	theme	HB	840:841	arg1	122.5 min					850:858	122.5 min	850:858	122.5 min	850:858	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	5	24	theme	HB	840:841	arg1	flake					843:847	HB flake	840:847	HB flake (122.5 min)	840:859	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	6	25	theme	starch	1073:1078	arg1	digestibility					1080:1092	the lowest starch digestibility	1062:1092	the lowest starch digestibility	1062:1092	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	5	26	theme	digesta	992:998	arg1	viscosity					971:979	its high viscosity	962:979	its high viscosity of gastric digesta	962:998	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	9	27	theme	in	1599:1600	arg1	fermentation					1614:1625	in vitro fecal fermentation	1599:1625	in vitro fecal fermentation of highland barley foods	1599:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	8	28	theme	undigested	1329:1338	arg1	starch					1340:1345	undigested starch	1329:1345	undigested starch of Puffed HB after in vitro gastroduodenal digestion	1329:1398	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	0	29	theme	in	64:65	arg1	digestibility					80:92	starch digestibility	73:92	starch digestibility	73:92	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	3	30	dep	sand-roasting	526:538	arg1	HB					548:549	Puffed HB	541:549	Puffed HB	541:549	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	9	31	theme	fecal	1608:1612	arg1	fermentation					1614:1625	in vitro fecal fermentation	1599:1625	in vitro fecal fermentation of highland barley foods	1599:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	0	32	theme	starch	73:78	arg1	digestibility					80:92	starch digestibility	73:92	starch digestibility	73:92	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	5	33	theme	high	966:969	arg1	viscosity					971:979	its high viscosity	962:979	its high viscosity of gastric digesta	962:998	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	5	34	theme	Puffed	865:870	arg1	84.0 min					876:883	84.0 min	876:883	84.0 min	876:883	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	5	34	theme	Puffed	865:870	arg1	HB					872:873	Puffed HB	865:873	Puffed HB (84.0 min)	865:884	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	8	35	theme	HB	1357:1358	arg1	starch					1340:1345	undigested starch	1329:1345	undigested starch of Puffed HB after in vitro gastroduodenal digestion	1329:1398	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	36	theme	relative	710:717	arg1	crystallinity					719:731	relative crystallinity	710:731	relative crystallinity	710:731	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	9	37	theme	barley	1639:1644	arg1	foods					1646:1650	highland barley foods	1630:1650	highland barley foods	1630:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	8	38	theme	in	1366:1367	arg1	digestion					1390:1398	in vitro gastroduodenal digestion	1366:1398	in vitro gastroduodenal digestion	1366:1398	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	39	theme	starch	670:675	arg1	order					699:703	starch short-range molecular order	670:703	starch short-range molecular order	670:703	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	2	40	theme	processing	346:355	arg1	methods					357:363	different processing methods	336:363	different processing methods	336:363	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	0	41	dep	in	64:65	arg1	vitro					67:71	vitro	67:71	vitro	67:71	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	8	42	theme	gastroduodenal	1375:1388	arg1	digestion					1390:1398	in vitro gastroduodenal digestion	1366:1398	in vitro gastroduodenal digestion	1366:1398	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	43	theme	molecular	689:697	arg1	order					699:703	starch short-range molecular order	670:703	starch short-range molecular order	670:703	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	7	44	theme	Puffed	1184:1189	arg1	HB					1191:1192	Puffed HB	1184:1192	Puffed HB	1184:1192	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	2	45	theme	worldwide	432:440	arg1	barley					377:382	highland barley	368:382	highland barley	368:382	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	45	theme	worldwide	432:440	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	45	theme	worldwide	432:440	arg1	one					385:387	one	385:387	one	385:387	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	0	46	theme	wall	25:28	arg1	integrity					30:38	cell wall integrity	20:38	cell wall integrity	20:38	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	5	47	theme	slowest	902:908	arg1	rate					927:930	the slowest gastric emptying rate	898:930	the slowest gastric emptying rate	898:930	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	2	48	theme	whole	419:423	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	1	49	theme	cells	293:297	arg1	walls					299:303	cells walls	293:303	cells walls	293:303	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	5	50	theme	emptying	918:925	arg1	rate					927:930	the slowest gastric emptying rate	898:930	the slowest gastric emptying rate	898:930	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	7	51	theme	acids	1274:1278	arg1	production					1236:1245	a 21% and 18% higher in vitro production	1206:1245	a 21% and 18% higher in vitro production of total short-chain fatty acids	1206:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	8	52	theme	β-glucan	1439:1446	arg1	fermentation					1423:1434	in vitro fecal fermentation	1408:1434	in vitro fecal fermentation of β-glucan	1408:1446	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	6	53	dep	in	1007:1008	arg1	vitro					1010:1014	vitro	1010:1014	vitro	1010:1014	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	1	54	theme	compounds	224:232	arg1	composition					188:198	composition	188:198	composition	188:198	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	1	54	theme	compounds	224:232	arg1	bioavailability					205:219	bioavailability	205:219	bioavailability	205:219	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	1	54	theme	compounds	224:232	arg1	structure					177:185	structure	177:185	structure	177:185	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	4	55	dep	showed	597:602	arg1	had					625:627	had	625:627	showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake	597:745	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	1	56	theme	whole	237:241	arg1	grains					243:248	whole grains	237:248	whole grains	237:248	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	6	57	theme	damaged	1143:1149	arg1	structure					1160:1168	its less damaged cellular structure	1134:1168	its less damaged cellular structure	1134:1168	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	9	58	theme	wall	1518:1521	arg1	integrity					1523:1531	cell wall integrity	1513:1531	cell wall integrity	1513:1531	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	6	59	theme	Puffed	1042:1047	arg1	HB					1049:1050	Puffed HB	1042:1050	Puffed HB	1042:1050	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	9	60	dep	in	1564:1565	arg1	vitro					1567:1571	vitro	1567:1571	vitro	1567:1571	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	7	61	dep	in	1227:1228	arg1	vitro					1230:1234	vitro	1230:1234	vitro	1230:1234	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	7	62	theme	short-chain	1256:1266	arg1	acids					1274:1278	total short-chain fatty acids	1250:1278	total short-chain fatty acids	1250:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	9	63	dep	in	1599:1600	arg1	vitro					1602:1606	vitro	1602:1606	vitro	1602:1606	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	5	64	theme	gastric	765:771	arg1	t1/2					783:786	t1/2	783:786	t1/2	783:786	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	5	64	theme	gastric	765:771	arg1	emptying					773:780	gastric emptying	765:780	gastric emptying (t1/2)	765:787	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	9	65	theme	gastric	1546:1552	arg1	emptying					1554:1561	the gastric emptying	1542:1561	the gastric emptying	1542:1561	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	0	66	theme	barley	135:140	arg1	foods					142:146	highland barley foods	126:146	highland barley foods	126:146	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	3	67	dep	sand-roasting-milling	557:577	arg1	Tsamba					580:585	Tsamba	580:585	Tsamba	580:585	The processing methods applied were flaking-boiling (HB flake), sand-roasting (Puffed HB), and sand-roasting-milling (Tsamba).					
37254345	7	68	theme	higher	1220:1225	arg1	production					1236:1245	a 21% and 18% higher in vitro production	1206:1245	a 21% and 18% higher in vitro production of total short-chain fatty acids	1206:1278	Furthermore, Puffed HB resulted in a 21% and 18% higher in vitro production of total short-chain fatty acids than Tsamba and HB flake, respectively.					
37254345	1	69	from	bioavailability	205:219	arg1	grains					243:248	whole grains	237:248	whole grains	237:248	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	1	70	from	composition	188:198	arg1	grains					243:248	whole grains	237:248	whole grains	237:248	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	4	71	theme	starch	654:659	arg1	content					661:667	damaged starch content	646:667	damaged starch content	646:667	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	1	72	from	structure	177:185	arg1	grains					243:248	whole grains	237:248	whole grains	237:248	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	6	73	theme	lowest	1066:1071	arg1	digestibility					1080:1092	the lowest starch digestibility	1062:1092	the lowest starch digestibility	1062:1092	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	8	74	theme	Puffed	1350:1355	arg1	HB					1357:1358	Puffed HB	1350:1358	Puffed HB	1350:1358	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	75	theme	higher	629:634	arg1	levels					636:641	higher levels	629:641	higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity	629:731	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	4	76	theme	order	699:703	arg1	levels					636:641	higher levels	629:641	higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity	629:731	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	0	77	theme	fermentation	98:109	arg1	performance					111:121	fermentation performance	98:121	fermentation performance	98:121	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	9	78	theme	highland	1630:1637	arg1	foods					1646:1650	highland barley foods	1630:1650	highland barley foods	1630:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	2	79	theme	methods	357:363	arg1	effects					325:331	the effects	321:331	the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide,	321:441	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	5	80	theme	gastric	984:990	arg1	digesta					992:998	gastric digesta	984:998	gastric digesta	984:998	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	9	81	theme	foods	1646:1650	arg1	emptying					1554:1561	the gastric emptying	1542:1561	the gastric emptying	1542:1561	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	9	81	theme	foods	1646:1650	arg1	fermentation					1614:1625	in vitro fecal fermentation	1599:1625	in vitro fecal fermentation of highland barley foods	1599:1650	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	9	81	theme	foods	1646:1650	arg1	digestibility					1580:1592	in vitro starch digestibility	1564:1592	in vitro starch digestibility	1564:1592	Our study provided insight into the potential mechanisms of how cell wall integrity affected the gastric emptying, in vitro starch digestibility, and in vitro fecal fermentation of highland barley foods.					
37254345	2	82	theme	different	336:344	arg1	methods					357:363	different processing methods	336:363	different processing methods	336:363	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	0	83	theme	cell	20:23	arg1	integrity					30:38	cell wall integrity	20:38	cell wall integrity	20:38	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	8	84	theme	in	1408:1409	arg1	fermentation					1423:1434	in vitro fecal fermentation	1408:1434	in vitro fecal fermentation of β-glucan	1408:1446	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	85	theme	short-range	677:687	arg1	order					699:703	starch short-range molecular order	670:703	starch short-range molecular order	670:703	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	0	86	theme	integrity	30:38	arg1	contribution					4:15	The contribution	0:15	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.	0:147	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	2	87	theme	grains	425:430	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	8	88	theme	fecal	1417:1421	arg1	fermentation					1423:1434	in vitro fecal fermentation	1408:1434	in vitro fecal fermentation of β-glucan	1408:1446	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	1	89	dep	structure	177:185	arg1	the					173:175	the	173:175	the	173:175	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	2	90	theme	highland	368:375	arg1	barley					377:382	highland barley	368:382	highland barley	368:382	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	90	theme	highland	368:375	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	2	90	theme	highland	368:375	arg1	one					385:387	one	385:387	one	385:387	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	0	91	theme	gastric	43:49	arg1	emptying					51:58	gastric emptying	43:58	gastric emptying	43:58	The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods.					
37254345	5	92	theme	gastric	910:916	arg1	rate					927:930	the slowest gastric emptying rate	898:930	the slowest gastric emptying rate	898:930	The half-time of gastric emptying (t1/2) was the slowest for Tsamba (132.3 min) compared to HB flake (122.5 min) and Puffed HB (84.0 min), indicating the slowest gastric emptying rate, which could be attributed to its high viscosity of gastric digesta.					
37254345	6	93	theme	in	1007:1008	arg1	digestion					1031:1039	in vitro gastroduodenal digestion	1007:1039	in vitro gastroduodenal digestion	1007:1039	After in vitro gastroduodenal digestion, Puffed HB exhibited the lowest starch digestibility and the least amount of β-glucan due to its less damaged cellular structure.					
37254345	2	94	theme	produced	410:417	arg1	worldwide					432:440	the mostly widely produced whole grains worldwide	392:440	the mostly widely produced whole grains worldwide	392:440	In this study, the effects of different processing methods on highland barley, one of the mostly widely produced whole grains worldwide, were investigated.					
37254345	1	95	theme	walls	299:303	arg1	processing					266:275	processing	266:275	processing	266:275	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	1	95	theme	walls	299:303	arg1	role					285:288	the role	281:288	the role of cells walls	281:303	Studies have shown that the structure, composition, and bioavailability of compounds in whole grains are affected by processing and the role of cells walls.					
37254345	4	96	theme	crystallinity	719:731	arg1	levels					636:641	higher levels	629:641	higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity	629:731	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37254345	8	97	dep	in	1366:1367	arg1	vitro					1369:1373	vitro	1369:1373	vitro	1369:1373	Besides, undigested starch of Puffed HB after in vitro gastroduodenal digestion delayed in vitro fecal fermentation of β-glucan.					
37254345	4	98	theme	HB	738:739	arg1	flake					741:745	HB flake	738:745	HB flake	738:745	Results showed Puffed HB and Tsamba had higher levels of damaged starch content, starch short-range molecular order, and relative crystallinity than HB flake.					
37364945	7	0	theme	water	1450:1454	arg1	interactions					1456:1467	the water interactions	1446:1467	the water interactions of CNF-based products	1446:1489	WBE shows great potential for managing the water interactions of CNF-based products.					
37364945	2	1	theme	natural	303:309	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	1	theme	natural	303:309	arg1	source					311:316	an underrated natural source	289:316	an underrated natural source of bioactive phenolic compounds	289:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	0	2	theme	bark	77:80	arg1	extract					82:88	willow bark extract	70:88	willow bark extract	70:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	2	3	theme	underrated	292:301	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	3	theme	underrated	292:301	arg1	source					311:316	an underrated natural source	289:316	an underrated natural source of bioactive phenolic compounds	289:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	5	4	theme	CNF	1197:1199	arg1	network					1201:1207	the CNF network	1193:1207	the CNF network in aqueous environment	1193:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	5	theme	flocculation	1074:1085	arg1	tendency					1087:1094	the flocculation tendency	1070:1094	the flocculation tendency	1070:1094	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	6	theme	pure	1115:1118	arg1	CNFs					1140:1143	pure and salt-containing CNFs	1115:1143	pure and salt-containing CNFs	1115:1143	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	2	7	used	used	257:260	arg2	we					254:255	we	254:255	we	254:255	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	5	8	from	environment	1220:1230	arg1	integrity					1180:1188	the structural integrity	1165:1188	the structural integrity of the CNF network in aqueous environment	1165:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	7	9	theme	great	1417:1421	arg1	potential					1423:1431	great potential	1417:1431	great potential for managing the water interactions of CNF-based products	1417:1489	WBE shows great potential for managing the water interactions of CNF-based products.					
37364945	5	10	from	network	1201:1207	arg1	environment					1220:1230	aqueous environment	1212:1230	aqueous environment	1212:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	3	11	theme	native	494:499	arg1	CNFs					527:530	native, mechanically fibrillated CNFs	494:530	native, mechanically fibrillated CNFs	494:530	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	5	12	from	flowability	1007:1017	arg1	strains					1050:1056	high shear strains	1039:1056	high shear strains	1039:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	13	theme	high	1039:1042	arg1	strains					1050:1056	high shear strains	1039:1056	high shear strains	1039:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	3	14	theme	WBE	480:482	arg1	introduction					464:475	the introduction	460:475	the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs	460:554	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	5	15	theme	salt	808:811	arg1	ions					813:816	the salt ions	804:816	the salt ions	804:816	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	6	16	theme	thorough	1341:1348	arg1	investigations					1350:1363	more thorough investigations	1336:1363	more thorough investigations of biocompatibility of natural materials	1336:1404	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	3	17	theme	5-7	664:666	arg1	times					668:672	5-7 times	664:672	5-7 times	664:672	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	2	18	theme	mechanical	423:432	arg1	properties					434:443	their mechanical properties	417:443	their mechanical properties	417:443	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	1	19	used	used	137:140	arg2	CNFs					114:117	CNFs	114:117	CNFs	114:117	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	1	19	used	used	137:140	arg2	nanofibrils					101:111	Cellulose nanofibrils	91:111	Cellulose nanofibrils (CNFs)	91:118	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	1	19	used	used	137:140	arg2	precursors					145:154	precursors	145:154	precursors for foams, films and composites, where water interactions are of great importance	145:236	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	6	20	theme	biocompatibility	1368:1383	arg1	investigations					1350:1363	more thorough investigations	1336:1363	more thorough investigations of biocompatibility of natural materials	1336:1404	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	2	21	theme	compounds	340:348	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	21	theme	compounds	340:348	arg1	source					311:316	an underrated natural source	289:316	an underrated natural source of bioactive phenolic compounds	289:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	3	22	from	ratio	643:647	arg1	water					652:656	water	652:656	water	652:656	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	4	23	theme	chemical	686:693	arg1	analysis					695:702	A detailed chemical analysis	675:702	A detailed chemical analysis	675:702	A detailed chemical analysis revealed that WBE is composed of several phenolic compounds in addition to potassium salts.					
37364945	2	24	theme	phenolic	331:338	arg1	compounds					340:348	bioactive phenolic compounds	321:348	bioactive phenolic compounds	321:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	5	25	from	strains	1050:1056	arg1	flowability					1007:1017	the flowability	1003:1017	the flowability of the hydrogels at high shear strains	1003:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	25	from	strains	1050:1056	arg1	hydrogels					1026:1034	the hydrogels	1022:1034	the hydrogels at high shear strains	1022:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	1	26	theme	Cellulose	91:99	arg1	precursors					145:154	precursors	145:154	precursors for foams, films and composites, where water interactions are of great importance	145:236	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	1	26	theme	Cellulose	91:99	arg1	CNFs					114:117	CNFs	114:117	CNFs	114:117	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	1	26	theme	Cellulose	91:99	arg1	nanofibrils					101:111	Cellulose nanofibrils	91:111	Cellulose nanofibrils (CNFs)	91:118	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	7	27	theme	CNF-based	1472:1480	arg1	products					1482:1489	CNF-based products	1472:1489	CNF-based products	1472:1489	WBE shows great potential for managing the water interactions of CNF-based products.					
37364945	2	28	theme	bioactive	321:329	arg1	compounds					340:348	bioactive phenolic compounds	321:348	bioactive phenolic compounds	321:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	29	theme	CNF	381:383	arg1	hydrogels					385:393	CNF hydrogels	381:393	CNF hydrogels	381:393	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	4	30	theme	detailed	677:684	arg1	analysis					695:702	A detailed chemical analysis	675:702	A detailed chemical analysis	675:702	A detailed chemical analysis revealed that WBE is composed of several phenolic compounds in addition to potassium salts.					
37364945	6	31	theme	hemolysis	1281:1289	arg1	activity					1291:1298	hemolysis activity	1281:1298	hemolysis activity	1281:1298	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	5	32	theme	important	975:983	arg1	role					985:988	an important role	972:988	an important role	972:988	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	2	33	theme	bark	269:272	arg1	source					311:316	an underrated natural source	289:316	an underrated natural source of bioactive phenolic compounds	289:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	33	theme	bark	269:272	arg1	WBE					283:285	WBE	283:285	WBE	283:285	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	33	theme	bark	269:272	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	33	theme	bark	269:272	arg1	modifier					368:375	a plant-based modifier	354:375	a plant-based modifier for CNF hydrogels	354:393	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	0	34	theme	water	11:15	arg1	interactions					17:28	the water interactions	7:28	the water interactions of cellulose nanofibril hydrogels using willow bark extract	7:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	3	35	theme	hydrogels	606:614	arg1	modulus					591:597	the storage modulus	579:597	the storage modulus of the hydrogels	579:614	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	2	36	theme	willow	262:267	arg1	source					311:316	an underrated natural source	289:316	an underrated natural source of bioactive phenolic compounds	289:348	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	36	theme	willow	262:267	arg1	WBE					283:285	WBE	283:285	WBE	283:285	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	36	theme	willow	262:267	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	36	theme	willow	262:267	arg1	modifier					368:375	a plant-based modifier	354:375	a plant-based modifier for CNF hydrogels	354:393	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	37	theme	plant-based	356:366	arg1	extract					274:280	willow bark extract	262:280	willow bark extract (WBE)	262:286	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	2	37	theme	plant-based	356:366	arg1	modifier					368:375	a plant-based modifier	354:375	a plant-based modifier for CNF hydrogels	354:393	In this study, we used willow bark extract (WBE), an underrated natural source of bioactive phenolic compounds, as a plant-based modifier for CNF hydrogels, without compromising their mechanical properties.					
37364945	0	38	theme	cellulose	33:41	arg1	hydrogels					54:62	cellulose nanofibril hydrogels	33:62	cellulose nanofibril hydrogels using willow bark extract	33:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	5	39	theme	salt-containing	1124:1138	arg1	CNFs					1140:1143	pure and salt-containing CNFs	1115:1143	pure and salt-containing CNFs	1115:1143	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	7	40	theme	products	1482:1489	arg1	interactions					1456:1467	the water interactions	1446:1467	the water interactions of CNF-based products	1446:1489	WBE shows great potential for managing the water interactions of CNF-based products.					
37364945	6	41	theme	bark	1258:1261	arg1	extract					1263:1269	the willow bark extract	1247:1269	the willow bark extract	1247:1269	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	6	42	theme	natural	1388:1394	arg1	materials					1396:1404	natural materials	1388:1404	natural materials	1388:1404	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	1	43	theme	water	195:199	arg1	interactions					201:212	water interactions	195:212	water interactions	195:212	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
37364945	0	44	theme	hydrogels	54:62	arg1	interactions					17:28	the water interactions	7:28	the water interactions of cellulose nanofibril hydrogels using willow bark extract	7:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	6	45	theme	willow	1251:1256	arg1	extract					1263:1269	the willow bark extract	1247:1269	the willow bark extract	1247:1269	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	5	46	theme	hydrogels	1026:1034	arg1	flowability					1007:1017	the flowability	1003:1017	the flowability of the hydrogels at high shear strains	1003:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	4	47	theme	potassium	779:787	arg1	salts					789:793	potassium salts	779:793	potassium salts	779:793	A detailed chemical analysis revealed that WBE is composed of several phenolic compounds in addition to potassium salts.					
37364945	5	48	theme	shear	1044:1048	arg1	strains					1050:1056	high shear strains	1039:1056	high shear strains	1039:1056	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	6	49	theme	materials	1396:1404	arg1	biocompatibility					1368:1383	biocompatibility	1368:1383	biocompatibility of natural materials	1368:1404	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	0	50	theme	nanofibril	43:52	arg1	hydrogels					54:62	cellulose nanofibril hydrogels	33:62	cellulose nanofibril hydrogels using willow bark extract	33:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	5	51	from	integrity	1180:1188	arg1	environment					1220:1230	aqueous environment	1212:1230	aqueous environment	1212:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	3	52	theme	swelling	634:641	arg1	ratio					643:647	their swelling ratio	628:647	their swelling ratio in water up to 5-7 times	628:672	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	3	53	theme	TEMPO-oxidized	536:549	arg1	CNFs					551:554	TEMPO-oxidized CNFs	536:554	TEMPO-oxidized CNFs	536:554	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	5	54	theme	denser	868:873	arg1	networks					879:886	denser CNF networks	868:886	denser CNF networks	868:886	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	4	55	theme	several	737:743	arg1	compounds					754:762	several phenolic compounds	737:762	several phenolic compounds in addition to potassium salts	737:793	A detailed chemical analysis revealed that WBE is composed of several phenolic compounds in addition to potassium salts.					
37364945	3	56	theme	storage	583:589	arg1	modulus					591:597	the storage modulus	579:597	the storage modulus of the hydrogels	579:614	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	5	57	theme	CNF	875:877	arg1	networks					879:886	denser CNF networks	868:886	denser CNF networks	868:886	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	58	located	observed	1103:1110	arg2	tendency					1087:1094	the flocculation tendency	1070:1094	the flocculation tendency	1070:1094	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	58	located	observed	1103:1110	arg1	CNFs					1140:1143	pure and salt-containing CNFs	1115:1143	pure and salt-containing CNFs	1115:1143	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	59	theme	phenolic	893:900	arg1	compounds					902:910	the phenolic compounds - which adsorbed readily on the cellulose surfaces -	889:963	the phenolic compounds - which adsorbed readily on the cellulose surfaces -	889:963	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	3	60	dep	native	494:499	arg1	fibrillated					515:525	fibrillated	515:525	fibrillated	515:525	We found that the introduction of WBE into both native, mechanically fibrillated CNFs and TEMPO-oxidized CNFs increased considerably the storage modulus of the hydrogels and reduced their swelling ratio in water up to 5-7 times.					
37364945	0	61	theme	willow	70:75	arg1	extract					82:88	willow bark extract	70:88	willow bark extract	70:88	Tuning the water interactions of cellulose nanofibril hydrogels using willow bark extract.					
37364945	5	62	theme	network	1201:1207	arg1	integrity					1180:1188	the structural integrity	1165:1188	the structural integrity of the CNF network in aqueous environment	1165:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	63	theme	cellulose	944:952	arg1	surfaces					954:961	the cellulose surfaces	940:961	the cellulose surfaces	940:961	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	64	theme	aqueous	1212:1218	arg1	environment					1220:1230	aqueous environment	1212:1230	aqueous environment	1212:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	5	65	theme	structural	1169:1178	arg1	integrity					1180:1188	the structural integrity	1165:1188	the structural integrity of the CNF network in aqueous environment	1165:1230	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	6	66	theme	investigations	1350:1363	arg1	importance					1322:1331	the importance	1318:1331	the importance of more thorough investigations of biocompatibility of natural materials	1318:1404	Surprisingly, the willow bark extract exhibited hemolysis activity, which highlights the importance of more thorough investigations of biocompatibility of natural materials.					
37364945	4	67	theme	phenolic	745:752	arg1	compounds					754:762	several phenolic compounds	737:762	several phenolic compounds in addition to potassium salts	737:793	A detailed chemical analysis revealed that WBE is composed of several phenolic compounds in addition to potassium salts.					
37364945	5	68	dep	compounds	902:910	arg1	adsorbed					920:927	adsorbed	920:927	adsorbed readily on the cellulose surfaces	920:961	Whereas the salt ions reduced the repulsion between fibrils and created denser CNF networks, the phenolic compounds - which adsorbed readily on the cellulose surfaces - played an important role in assisting the flowability of the hydrogels at high shear strains by reducing the flocculation tendency, often observed in pure and salt-containing CNFs, and contributed to the structural integrity of the CNF network in aqueous environment.					
37364945	1	69	theme	great	221:225	arg1	importance					227:236	great importance	221:236	great importance	221:236	Cellulose nanofibrils (CNFs) are increasingly used as precursors for foams, films and composites, where water interactions are of great importance.					
35290806	7	0	theme	current	1282:1288	arg1	density					1290:1296	the current density	1278:1296	the current density	1278:1296	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	7	1	theme	good	1208:1211	arg1	capability					1218:1227	good rate capability	1208:1227	good rate capability	1208:1227	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	4	2	theme	fabric	755:760	arg1	surface					706:712	the surface	702:712	the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF)	702:768	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	3	3	from	area	579:582	arg1	supercapacitors					626:640	the supercapacitors	622:640	the supercapacitors	622:640	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	6	4	theme	specific	1074:1081	arg1	capacitance					1083:1093	a prominent specific capacitance	1062:1093	a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2	1062:1125	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	3	5	dep	the	427:429	arg1	help					431:434	help	431:434	help	431:434	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	1	6	theme	hierarchical	204:215	arg1	structure					224:232	hierarchical porous structure	204:232	hierarchical porous structure	204:232	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	6	7	theme	prominent	1064:1072	arg1	capacitance					1083:1093	a prominent specific capacitance	1062:1093	a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2	1062:1125	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	8	8	theme	maximum	1472:1478	arg1	capacitance					1495:1505	the maximum areal specific capacitance	1468:1505	the maximum areal specific capacitance of 1748.0 mF·cm-2	1468:1523	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	9	theme	0.88 mW·cm-2	1613:1624	arg1	density					1602:1608	a power density	1594:1608	a power density of 0.88 mW·cm-2	1594:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	9	10	theme	high-performance	1725:1740	arg1	substrate					1762:1770	high-performance flexible conductive substrate	1725:1770	high-performance flexible conductive substrate in the supercapacitors	1725:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	8	11	theme	fabric	1440:1445	arg1	electrodes					1447:1456	the optimized composite fabric electrodes	1416:1456	the optimized composite fabric electrodes	1416:1456	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	4	12	theme	conductive	782:791	arg1	framework					793:801	the conductive framework	778:801	the conductive framework	778:801	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	6	13	theme	composite	964:972	arg1	electrode					974:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	2	14	theme	loading	323:329	arg1	mass					331:334	a high loading mass	316:334	a high loading mass of electroactive materials for outstanding electrochemical performance	316:405	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	6	15	theme	high	1001:1004	arg1	conductivity					1017:1028	a high electrical conductivity	999:1028	a high electrical conductivity of 285.9 ± 1.2 S·cm-1	999:1050	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	3	16	theme	flexible	588:595	arg1	substrates					608:617	flexible conductive substrates	588:617	flexible conductive substrates	588:617	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	1	17	used	used	130:133	arg2	substrates					151:160	freestanding substrates	138:160	freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility	138:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	1	17	used	used	130:133	arg2	Fabrics					112:118	Fabrics	112:118	Fabrics	112:118	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	4	18	theme	nonwoven	746:753	arg1	c-CVF					763:767	c-CVF	763:767	c-CVF	763:767	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	18	theme	nonwoven	746:753	arg1	fabric					755:760	crosslinked chitosan-viscose nonwoven fabric	717:760	crosslinked chitosan-viscose nonwoven fabric (c-CVF)	717:768	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	6	19	theme	PPy/MWCNT/c-CVF	948:962	arg1	electrode					974:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	2	20	theme	high	318:321	arg1	mass					331:334	a high loading mass	316:334	a high loading mass of electroactive materials for outstanding electrochemical performance	316:405	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	1	21	theme	porous	217:222	arg1	structure					224:232	hierarchical porous structure	204:232	hierarchical porous structure	204:232	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	3	22	theme	swelling	444:451	arg1	property					453:460	high swelling property	439:460	high swelling property of chitosan	439:472	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	6	23	theme	optimized	938:946	arg1	electrode					974:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode	934:982	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	7	24	theme	high	1187:1190	arg1	flexibility					1192:1202	a high flexibility	1185:1202	a high flexibility	1185:1202	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	4	25	theme	multi-walled	649:660	arg1	MWCNTs					680:685	MWCNTs	680:685	MWCNTs	680:685	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	25	theme	multi-walled	649:660	arg1	nanotubes					669:677	multi-walled carbon nanotubes	649:677	multi-walled carbon nanotubes (MWCNTs)	649:686	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	3	26	theme	chitosan-viscose	479:494	arg1	fabric					505:510	the chitosan-viscose nonwoven fabric	475:510	the chitosan-viscose nonwoven fabric (CVF)	475:516	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	3	26	theme	chitosan-viscose	479:494	arg1	CVF					513:515	CVF	513:515	CVF	513:515	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	7	27	theme	%	1247:1247	arg1	capacitance					1249:1259	the 70.3% capacitance	1239:1259	the 70.3% capacitance	1239:1259	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	6	28	from	2 mA·cm-2	1117:1125	arg1	conductivity					1017:1028	a high electrical conductivity	999:1028	a high electrical conductivity of 285.9 ± 1.2 S·cm-1	999:1050	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	6	28	from	2 mA·cm-2	1117:1125	arg1	capacitance					1083:1093	a prominent specific capacitance	1062:1093	a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2	1062:1125	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	9	29	from	substrate	1762:1770	arg1	supercapacitors					1779:1793	the supercapacitors	1775:1793	the supercapacitors	1775:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	3	30	theme	chitosan	465:472	arg1	property					453:460	high swelling property	439:460	high swelling property of chitosan	439:472	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	0	31	theme	Swelling-reconstructed	0:21	arg1	chitosan-viscose					23:38	Swelling-reconstructed chitosan-viscose	0:38	Swelling-reconstructed chitosan-viscose	0:38	Swelling-reconstructed chitosan-viscose nonwoven fabric for high-performance quasi-solid-state supercapacitors.					
35290806	2	32	theme	materials	353:361	arg1	mass					331:334	a high loading mass	316:334	a high loading mass of electroactive materials for outstanding electrochemical performance	316:405	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	9	33	theme	blended	1687:1693	arg1	structure					1711:1719	the blended nonwoven fabric structure	1683:1719	the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors	1683:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	1	34	theme	excellent	238:246	arg1	flexibility					259:269	excellent mechanical flexibility	238:269	excellent mechanical flexibility	238:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	5	35	theme	in-situ	852:858	arg1	polymerization					872:885	in-situ interfacial polymerization	852:885	in-situ interfacial polymerization	852:885	Subsequently, polypyrrole (PPy) is deposited by in-situ interfacial polymerization on the above conductive MWCNT/c-CVF substrate.					
35290806	7	36	theme	composite	1151:1159	arg1	electrode					1161:1169	the prepared composite electrode	1138:1169	the prepared composite electrode	1138:1169	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	9	37	theme	flexible	1742:1749	arg1	substrate					1762:1770	high-performance flexible conductive substrate	1725:1770	high-performance flexible conductive substrate in the supercapacitors	1725:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	2	38	theme	electroactive	339:351	arg1	materials					353:361	electroactive materials	339:361	electroactive materials	339:361	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	1	39	theme	mechanical	248:257	arg1	flexibility					259:269	excellent mechanical flexibility	238:269	excellent mechanical flexibility	238:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	5	40	theme	interfacial	860:870	arg1	polymerization					872:885	in-situ interfacial polymerization	852:885	in-situ interfacial polymerization	852:885	Subsequently, polypyrrole (PPy) is deposited by in-situ interfacial polymerization on the above conductive MWCNT/c-CVF substrate.					
35290806	6	41	theme	285.9 ± 1.2 S·cm-1	1033:1050	arg1	conductivity					1017:1028	a high electrical conductivity	999:1028	a high electrical conductivity of 285.9 ± 1.2 S·cm-1	999:1050	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	6	41	theme	285.9 ± 1.2 S·cm-1	1033:1050	arg1	capacitance					1083:1093	a prominent specific capacitance	1062:1093	a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2	1062:1125	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	3	42	theme	surface	571:577	arg1	area					579:582	its specific surface area	558:582	its specific surface area for flexible conductive substrates in the supercapacitors	558:640	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	8	43	theme	energy	1558:1563	arg1	density					1565:1571	the outstanding energy density	1542:1571	the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2	1542:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	4	44	link	crosslinked	717:727	arg1	c-CVF					763:767	c-CVF	763:767	c-CVF	763:767	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	44	link	crosslinked	717:727	arg1	fabric					755:760	crosslinked chitosan-viscose nonwoven fabric	717:760	crosslinked chitosan-viscose nonwoven fabric (c-CVF)	717:768	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	0	45	theme	high-performance	60:75	arg1	supercapacitors					95:109	high-performance quasi-solid-state supercapacitors	60:109	high-performance quasi-solid-state supercapacitors	60:109	Swelling-reconstructed chitosan-viscose nonwoven fabric for high-performance quasi-solid-state supercapacitors.					
35290806	8	46	theme	symmetric	1369:1377	arg1	supercapacitor					1379:1392	the quasi-solid-state symmetric supercapacitor	1347:1392	the quasi-solid-state symmetric supercapacitor	1347:1392	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	47	theme	outstanding	1546:1556	arg1	density					1565:1571	the outstanding energy density	1542:1571	the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2	1542:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	3	48	theme	nonwoven	496:503	arg1	fabric					505:510	the chitosan-viscose nonwoven fabric	475:510	the chitosan-viscose nonwoven fabric (CVF)	475:516	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	3	48	theme	nonwoven	496:503	arg1	CVF					513:515	CVF	513:515	CVF	513:515	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	5	49	theme	conductive	900:909	arg1	substrate					923:931	the above conductive MWCNT/c-CVF substrate	890:931	the above conductive MWCNT/c-CVF substrate	890:931	Subsequently, polypyrrole (PPy) is deposited by in-situ interfacial polymerization on the above conductive MWCNT/c-CVF substrate.					
35290806	7	50	theme	prepared	1142:1149	arg1	electrode					1161:1169	the prepared composite electrode	1138:1169	the prepared composite electrode	1138:1169	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	8	51	theme	quasi-solid-state	1351:1367	arg1	supercapacitor					1379:1392	the quasi-solid-state symmetric supercapacitor	1347:1392	the quasi-solid-state symmetric supercapacitor	1347:1392	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	52	theme	specific	1486:1493	arg1	capacitance					1495:1505	the maximum areal specific capacitance	1468:1505	the maximum areal specific capacitance of 1748.0 mF·cm-2	1468:1523	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	9	53	theme	nonwoven	1695:1702	arg1	structure					1711:1719	the blended nonwoven fabric structure	1683:1719	the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors	1683:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	3	54	theme	high	439:442	arg1	property					453:460	high swelling property	439:460	high swelling property of chitosan	439:472	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	6	55	theme	electrical	1006:1015	arg1	conductivity					1017:1028	a high electrical conductivity	999:1028	a high electrical conductivity of 285.9 ± 1.2 S·cm-1	999:1050	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	8	56	theme	1748.0 mF·cm-2	1510:1523	arg1	capacitance					1495:1505	the maximum areal specific capacitance	1468:1505	the maximum areal specific capacitance of 1748.0 mF·cm-2	1468:1523	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	0	57	theme	quasi-solid-state	77:93	arg1	supercapacitors					95:109	high-performance quasi-solid-state supercapacitors	60:109	high-performance quasi-solid-state supercapacitors	60:109	Swelling-reconstructed chitosan-viscose nonwoven fabric for high-performance quasi-solid-state supercapacitors.					
35290806	3	58	theme	conductive	597:606	arg1	substrates					608:617	flexible conductive substrates	588:617	flexible conductive substrates	588:617	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	7	59	theme	rate	1213:1216	arg1	capability					1218:1227	good rate capability	1208:1227	good rate capability	1208:1227	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	1	60	theme	energy	166:171	arg1	devices					181:187	energy storage devices	166:187	energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility	166:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	6	61	theme	10112.9 mF·cm-2	1098:1112	arg1	conductivity					1017:1028	a high electrical conductivity	999:1028	a high electrical conductivity of 285.9 ± 1.2 S·cm-1	999:1050	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	6	61	theme	10112.9 mF·cm-2	1098:1112	arg1	capacitance					1083:1093	a prominent specific capacitance	1062:1093	a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2	1062:1125	The optimized PPy/MWCNT/c-CVF composite electrode shows not only a high electrical conductivity of 285.9 ± 1.2 S·cm-1, but also a prominent specific capacitance of 10112.9 mF·cm-2 at 2 mA·cm-2.					
35290806	8	62	theme	155.4 μWh·cm-2	1576:1589	arg1	density					1565:1571	the outstanding energy density	1542:1571	the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2	1542:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	62	theme	155.4 μWh·cm-2	1576:1589	arg1	2 mA·cm-2					1528:1536	2 mA·cm-2	1528:1536	2 mA·cm-2	1528:1536	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	9	63	theme	conductive	1751:1760	arg1	substrate					1762:1770	high-performance flexible conductive substrate	1725:1770	high-performance flexible conductive substrate in the supercapacitors	1725:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	4	64	theme	crosslinked	717:727	arg1	c-CVF					763:767	c-CVF	763:767	c-CVF	763:767	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	64	theme	crosslinked	717:727	arg1	fabric					755:760	crosslinked chitosan-viscose nonwoven fabric	717:760	crosslinked chitosan-viscose nonwoven fabric (c-CVF)	717:768	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	1	65	theme	storage	173:179	arg1	devices					181:187	energy storage devices	166:187	energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility	166:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	1	66	theme	freestanding	138:149	arg1	Fabrics					112:118	Fabrics	112:118	Fabrics	112:118	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	1	66	theme	freestanding	138:149	arg1	substrates					151:160	freestanding substrates	138:160	freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility	138:269	Fabrics are often used as freestanding substrates for energy storage devices owing to their hierarchical porous structure and excellent mechanical flexibility.					
35290806	4	67	theme	carbon	662:667	arg1	MWCNTs					680:685	MWCNTs	680:685	MWCNTs	680:685	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	67	theme	carbon	662:667	arg1	nanotubes					669:677	multi-walled carbon nanotubes	649:677	multi-walled carbon nanotubes (MWCNTs)	649:686	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	8	68	theme	power	1596:1600	arg1	density					1602:1608	a power density	1594:1608	a power density of 0.88 mW·cm-2	1594:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	9	69	theme	effective	1649:1657	arg1	approach					1659:1666	an effective approach	1646:1666	an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors	1646:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	2	70	theme	outstanding	367:377	arg1	performance					395:405	outstanding electrochemical performance	367:405	outstanding electrochemical performance	367:405	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	8	71	theme	optimized	1420:1428	arg1	electrodes					1447:1456	the optimized composite fabric electrodes	1416:1456	the optimized composite fabric electrodes	1416:1456	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	2	72	theme	electrochemical	379:393	arg1	performance					395:405	outstanding electrochemical performance	367:405	outstanding electrochemical performance	367:405	However, it is still a challenge to achieve a high loading mass of electroactive materials for outstanding electrochemical performance.					
35290806	8	73	theme	areal	1480:1484	arg1	capacitance					1495:1505	the maximum areal specific capacitance	1468:1505	the maximum areal specific capacitance of 1748.0 mF·cm-2	1468:1523	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	74	theme	composite	1430:1438	arg1	electrodes					1447:1456	the optimized composite fabric electrodes	1416:1456	the optimized composite fabric electrodes	1416:1456	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	4	75	theme	chitosan-viscose	729:744	arg1	c-CVF					763:767	c-CVF	763:767	c-CVF	763:767	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	4	75	theme	chitosan-viscose	729:744	arg1	fabric					755:760	crosslinked chitosan-viscose nonwoven fabric	717:760	crosslinked chitosan-viscose nonwoven fabric (c-CVF)	717:768	Then, multi-walled carbon nanotubes (MWCNTs) are coated on the surface of crosslinked chitosan-viscose nonwoven fabric (c-CVF) to form the conductive framework.					
35290806	5	76	theme	MWCNT/c-CVF	911:921	arg1	substrate					923:931	the above conductive MWCNT/c-CVF substrate	890:931	the above conductive MWCNT/c-CVF substrate	890:931	Subsequently, polypyrrole (PPy) is deposited by in-situ interfacial polymerization on the above conductive MWCNT/c-CVF substrate.					
35290806	9	77	theme	fabric	1704:1709	arg1	structure					1711:1719	the blended nonwoven fabric structure	1683:1719	the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors	1683:1793	This work provides an effective approach to reconstruct the blended nonwoven fabric structure for high-performance flexible conductive substrate in the supercapacitors.					
35290806	7	78	theme	70.3	1243:1246	arg1	%					1247:1247	%	1247:1247	%	1247:1247	Moreover, the prepared composite electrode also exhibits a high flexibility and good rate capability, in which the 70.3% capacitance is retained when the current density increases from 2 mA·cm-2 to 10 mA·cm-2.					
35290806	3	79	theme	specific	562:569	arg1	area					579:582	its specific surface area	558:582	its specific surface area for flexible conductive substrates in the supercapacitors	558:640	In this work, with the help of high swelling property of chitosan, the chitosan-viscose nonwoven fabric (CVF) is successfully reconstructed to expand its specific surface area for flexible conductive substrates in the supercapacitors.					
35290806	8	80	from	density	1602:1608	arg1	density					1565:1571	the outstanding energy density	1542:1571	the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2	1542:1624	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35290806	8	80	from	density	1602:1608	arg1	2 mA·cm-2					1528:1536	2 mA·cm-2	1528:1536	2 mA·cm-2	1528:1536	Besides, the quasi-solid-state symmetric supercapacitor, being assembled with the optimized composite fabric electrodes, produces the maximum areal specific capacitance of 1748.0 mF·cm-2 at 2 mA·cm-2 and the outstanding energy density of 155.4 μWh·cm-2 at a power density of 0.88 mW·cm-2.					
35032269	4	0	theme	31.30 mg g-1	660:671	arg1	capacities					629:638	Adsorption capacities	618:638	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX	618:690	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	7	1	theme	reported	1336:1343	arg1	beads					1345:1349	the reported beads	1332:1349	the reported beads towards removing antibiotics from pharmaceutical industry wastewater	1332:1418	These results showed a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater.					
35032269	5	2	theme	composite	843:851	arg1	beads					853:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	6	3	theme	CFX	1009:1011	arg1	adsorption					984:993	The adsorption	980:993	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads	980:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	1	4	theme	tetracycline	248:259	arg1	antibiotics					308:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	1	5	theme	antibiotics	308:318	arg1	removal					237:243	the removal	233:243	the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	233:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	6	6	from	TC	998:999	arg1	surface					1020:1026	the surface	1016:1026	the surface of Fe3O4-functionalized MIL101(Fe) chitosan	1016:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	3	7	theme	pseudo-second-ord	497:513	arg1	model					526:530	pseudo-second-ord er kinetic model	497:530	pseudo-second-ord er kinetic model	497:530	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	0	8	from	streams	59:65	arg1	removal					23:29	Sustainable adsorptive removal	0:29	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.	0:129	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	3	9	theme	er	515:516	arg1	model					526:530	pseudo-second-ord er kinetic model	497:530	pseudo-second-ord er kinetic model	497:530	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	5	10	theme	chitosan	834:841	arg1	beads					853:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	5	11	theme	Fe3O4-functionalized	802:821	arg1	beads					853:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads	798:857	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	0	12	theme	composite	114:122	arg1	beads					124:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	1	13	theme	aqueous	325:331	arg1	streams					333:339	aqueous streams	325:339	aqueous streams	325:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	6	14	from	DC	1002:1003	arg1	surface					1020:1026	the surface	1016:1026	the surface of Fe3O4-functionalized MIL101(Fe) chitosan	1016:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	5	15	theme	remarkable	914:923	arg1	ability					938:944	a remarkable regeneration ability	912:944	a remarkable regeneration ability over up to 5 cycles	912:964	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	5	16	dep	5	957:957	arg1	to					954:955	to	954:955	to	954:955	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	1	17	theme	recyclable	161:170	arg1	beads					223:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads	161:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	161:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	0	18	theme	chitosan	105:112	arg1	beads					124:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	4	19	theme	composite	781:789	arg1	beads					791:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	5	20	theme	regeneration	925:936	arg1	ability					938:944	a remarkable regeneration ability	912:944	a remarkable regeneration ability over up to 5 cycles	912:964	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	1	21	theme	Fe3O4-functionalized	172:191	arg1	beads					223:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads	161:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	161:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	0	22	theme	adsorptive	12:21	arg1	removal					23:29	Sustainable adsorptive removal	0:29	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.	0:129	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	2	23	theme	contact	449:455	arg1	time					457:460	contact time	449:460	contact time	449:460	More than 99% removal efficiency for each antibiotic was achieved at optimum pH, dosage, concentration and contact time.					
35032269	6	24	theme	composite	1072:1080	arg1	beads					1082:1086	composite beads	1072:1086	composite beads	1072:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	4	25	theme	45.33	643:647	arg1	capacities					629:638	Adsorption capacities	618:638	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX	618:690	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	0	26	theme	Sustainable	0:10	arg1	removal					23:29	Sustainable adsorptive removal	0:29	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.	0:129	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	27	theme	π-π	1108:1110	arg1	interaction					1112:1122	the π-π interaction	1104:1122	the π-π interaction	1104:1122	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	5	28	theme	regeneration	886:897	arg1	ability					899:905	their regeneration ability	880:905	their regeneration ability	880:905	The Fe3O4-functionalized MIL101(Fe) chitosan composite beads were also tested for their regeneration ability, and a remarkable regeneration ability over up to 5 cycles was observed.					
35032269	0	29	theme	aqueous	51:57	arg1	streams					59:65	aqueous streams	51:65	aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads	51:128	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	30	theme	TC	998:999	arg1	adsorption					984:993	The adsorption	980:993	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads	980:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	6	31	theme	DC	1002:1003	arg1	adsorption					984:993	The adsorption	980:993	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads	980:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	6	32	theme	aqueous	1264:1270	arg1	solution					1272:1279	the aqueous solution	1260:1279	the aqueous solution	1260:1279	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	6	33	from	adsorption	984:993	arg1	surface					1020:1026	the surface	1016:1026	the surface of Fe3O4-functionalized MIL101(Fe) chitosan	1016:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	3	34	theme	kinetic	518:524	arg1	model					526:530	pseudo-second-ord er kinetic model	497:530	pseudo-second-ord er kinetic model	497:530	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	3	35	theme	coefficient	563:573	arg1	values					575:580	correlation coefficient values	551:580	correlation coefficient values close to 1	551:591	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	3	36	with	suitable	537:544	arg1	values					575:580	correlation coefficient values	551:580	correlation coefficient values close to 1	551:591	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	1	37	theme	doxycycline	267:277	arg1	antibiotics					308:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	6	38	theme	Fe	1059:1060	arg1	chitosan					1063:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	4	39	theme	33.20	650:654	arg1	capacities					629:638	Adsorption capacities	618:638	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX	618:690	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	2	40	dep	efficiency	364:373	arg1	%					354:354	%	354:354	%	354:354	More than 99% removal efficiency for each antibiotic was achieved at optimum pH, dosage, concentration and contact time.					
35032269	6	41	dep	TC	998:999	arg1	beads					1082:1086	composite beads	1072:1086	composite beads	1072:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	1	42	theme	chitosan	204:211	arg1	beads					223:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads	161:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	161:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	0	43	theme	antibiotics	34:44	arg1	removal					23:29	Sustainable adsorptive removal	0:29	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.	0:129	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	44	from	deprotonation	1223:1235	arg1	solution					1272:1279	the aqueous solution	1260:1279	the aqueous solution	1260:1279	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	6	45	theme	electrostatic	1139:1151	arg1	interaction					1153:1163	electrostatic interaction	1139:1163	electrostatic interaction between the antibiotics	1139:1187	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	1	46	theme	composite	213:221	arg1	beads					223:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads	161:227	recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	161:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	7	47	attach	removing	1359:1366	arg1	industry					1400:1407	industry	1400:1407	industry	1400:1407	These results showed a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater.					
35032269	7	47	attach	removing	1359:1366	arg2	beads					1345:1349	the reported beads	1332:1349	the reported beads towards removing antibiotics from pharmaceutical industry wastewater	1332:1418	These results showed a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater.					
35032269	6	48	theme	cation	1241:1246	arg1	exchange					1248:1255	cation exchange	1241:1255	cation exchange	1241:1255	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	6	49	from	exchange	1248:1255	arg1	solution					1272:1279	the aqueous solution	1260:1279	the aqueous solution	1260:1279	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	4	50	theme	chitosan	772:779	arg1	beads					791:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	2	51	theme	optimum	411:417	arg1	pH					419:420	optimum pH	411:420	optimum pH	411:420	More than 99% removal efficiency for each antibiotic was achieved at optimum pH, dosage, concentration and contact time.					
35032269	7	52	dep	industry	1400:1407	arg1	wastewater					1409:1418	wastewater	1409:1418	pharmaceutical industry wastewater	1385:1418	These results showed a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater.					
35032269	6	53	from	protonation	1210:1220	arg1	solution					1272:1279	the aqueous solution	1260:1279	the aqueous solution	1260:1279	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	7	54	theme	good	1305:1308	arg1	prospect					1310:1317	a good prospect	1303:1317	a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater	1303:1418	These results showed a good prospect for applying the reported beads towards removing antibiotics from pharmaceutical industry wastewater.					
35032269	3	55	theme	correlation	551:561	arg1	values					575:580	correlation coefficient values	551:580	correlation coefficient values close to 1	551:591	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	6	56	theme	MIL101	1052:1057	arg1	chitosan					1063:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	1	57	theme	ciprofloxacin	288:300	arg1	antibiotics					308:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics	248:318	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
35032269	4	58	theme	synthesized	728:738	arg1	beads					791:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	59	theme	Fe3O4-functionalized	1031:1050	arg1	chitosan					1063:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	Fe3O4-functionalized MIL101(Fe) chitosan	1031:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	3	60	theme	adsorption	472:481	arg1	isotherms					483:491	Langmuir adsorption isotherms	463:491	Langmuir adsorption isotherms	463:491	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	0	61	theme	Fe3O4-functionalized	73:92	arg1	beads					124:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Fe3O4-functionalized MIL101(Fe) chitosan composite beads	73:128	Sustainable adsorptive removal of antibiotics from aqueous streams using Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	2	62	theme	removal	356:362	arg1	efficiency					364:373	More than 99% removal efficiency	342:373	More than 99% removal efficiency for each antibiotic	342:393	More than 99% removal efficiency for each antibiotic was achieved at optimum pH, dosage, concentration and contact time.					
35032269	2	63	dep	%	354:354	arg1	99					352:353	99	352:353	99	352:353	More than 99% removal efficiency for each antibiotic was achieved at optimum pH, dosage, concentration and contact time.					
35032269	6	64	from	CFX	1009:1011	arg1	surface					1020:1026	the surface	1016:1026	the surface of Fe3O4-functionalized MIL101(Fe) chitosan	1016:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	3	65	theme	Langmuir	463:470	arg1	adsorption					472:481	Langmuir adsorption	463:481	Langmuir adsorption isotherms	463:491	Langmuir adsorption isotherms and pseudo-second-ord er kinetic model were suitable with correlation coefficient values close to 1 for all the antibiotics.					
35032269	4	66	theme	Adsorption	618:627	arg1	capacities					629:638	Adsorption capacities	618:638	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX	618:690	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	67	theme	chitosan	1063:1070	arg1	surface					1020:1026	the surface	1016:1026	the surface of Fe3O4-functionalized MIL101(Fe) chitosan	1016:1070	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	4	68	theme	Fe3O4-functionalized	740:759	arg1	beads					791:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads	724:795	Adsorption capacities of 45.33, 33.20 and 31.30 mg g-1 for TC, DC and CFX, respectively, were reported by the synthesized Fe3O4-functionalized MIL101(Fe) chitosan composite beads.					
35032269	6	69	from	surface	1020:1026	arg1	adsorption					984:993	The adsorption	980:993	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads	980:1086	The adsorption of TC, DC and CFX on the surface of Fe3O4-functionalized MIL101(Fe) chitosan composite beads was governed by the π-π interaction, H-bonding and electrostatic interaction between the antibiotics and adsorbent due to protonation, deprotonation and cation exchange in the aqueous solution.					
35032269	1	70	from	streams	333:339	arg1	removal					237:243	the removal	233:243	the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams	233:339	In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline (DC) and ciprofloxacin (CFX) antibiotics from aqueous streams.					
36863677	10	0	contain	has	935:937	arg1	NFC					931:933	NFC	931:933	NFC	931:933	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	10	0	contain	has	935:937	arg2	crystallinity					944:956	high crystallinity	939:956	high crystallinity	939:956	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	11	1	theme	thermal	1049:1055	arg1	stability					1057:1065	good thermal stability	1044:1065	good thermal stability	1044:1065	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	5	2	theme	Particle	391:398	arg1	homogeneity					400:410	Particle homogeneity	391:410	Particle homogeneity	391:410	Particle homogeneity, turbidity, and microstructure of the suspensions were evaluated.					
36863677	11	3	theme	Thermogravimetric	959:975	arg1	TGA					987:989	TGA	987:989	TGA	987:989	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	11	3	theme	Thermogravimetric	959:975	arg1	analysis					977:984	Thermogravimetric analysis	959:984	Thermogravimetric analysis (TGA)	959:990	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	13	4	from	score	1279:1283	arg1	index					1311:1315	a quality index	1301:1315	a quality index	1301:1315	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	9	5	theme	transmission	834:845	arg1	TEM					868:870	TEM	868:870	TEM	868:870	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	9	5	theme	transmission	834:845	arg1	microscopy					856:865	transmission electron microscopy	834:865	transmission electron microscopy (TEM)	834:871	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	13	6	theme	quality	1303:1309	arg1	index					1311:1315	a quality index	1301:1315	a quality index	1301:1315	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	13	7	theme	points	1291:1296	arg1	score					1279:1283	its score	1275:1283	its score of 72 points on a quality index	1275:1315	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	6	8	theme	physical-mechanical	511:529	arg1	properties					531:540	the optical and physical-mechanical properties	495:540	the optical and physical-mechanical properties of the nanopapers	495:558	Correspondingly, the optical and physical-mechanical properties of the nanopapers were investigated.					
36863677	9	9	theme	electron	847:854	arg1	TEM					868:870	TEM	868:870	TEM	868:870	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	9	9	theme	electron	847:854	arg1	microscopy					856:865	transmission electron microscopy	834:865	transmission electron microscopy (TEM)	834:871	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	1	10	dep	cactus	149:154	arg1	Cereus					156:161	Cereus	156:161	Cereus	156:161	In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC.					
36863677	10	11	theme	high	939:942	arg1	crystallinity					944:956	high crystallinity	939:956	high crystallinity	939:956	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	6	12	theme	optical	499:505	arg1	properties					531:540	the optical and physical-mechanical properties	495:540	the optical and physical-mechanical properties of the nanopapers	495:558	Correspondingly, the optical and physical-mechanical properties of the nanopapers were investigated.					
36863677	4	13	theme	quality	376:382	arg1	index					384:388	a quality index	374:388	a quality index	374:388	The NFC was characterized according to its properties and scored based on a quality index.					
36863677	7	14	theme	chemical	583:590	arg1	constituents					592:603	The chemical constituents	579:603	The chemical constituents of the material	579:619	The chemical constituents of the material were analyzed.					
36863677	11	15	theme	mechanical	1076:1085	arg1	properties					1087:1096	good mechanical properties	1071:1096	good mechanical properties	1071:1096	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	1	16	theme	cactus	149:154	arg1	DC					172:173	cactus Cereus jamacaru DC	149:173	cactus Cereus jamacaru DC	149:173	In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC.					
36863677	7	17	theme	material	612:619	arg1	constituents					592:603	The chemical constituents	579:603	The chemical constituents of the material	579:619	The chemical constituents of the material were analyzed.					
36863677	13	18	theme	facile	1364:1369	arg1	material					1323:1330	this material	1318:1330	this material	1318:1330	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	13	18	theme	facile	1364:1369	arg1	source					1387:1392	an attractive, facile, and innovative source	1349:1392	an attractive, facile, and innovative source for obtaining NFC	1349:1410	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	0	19	theme	nanopaper	62:70	arg1	production					72:81	nanopaper production	62:81	nanopaper production	62:81	Mandacaru cactus as a source of nanofibrillated cellulose for nanopaper production.					
36863677	9	20	theme	morphological	732:744	arg1	investigation					746:758	The morphological investigation	728:758	The morphological investigation	728:758	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	1	21	theme	jamacaru	163:170	arg1	DC					172:173	cactus Cereus jamacaru DC	149:173	cactus Cereus jamacaru DC	149:173	In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC.					
36863677	8	22	theme	suspension	716:725	arg1	stability					695:703	the stability	691:703	the stability of the NFC suspension	691:725	The sedimentation test and the zeta potential analyzed the stability of the NFC suspension.					
36863677	8	23	theme	NFC	712:714	arg1	suspension					716:725	the NFC suspension	708:725	the NFC suspension	708:725	The sedimentation test and the zeta potential analyzed the stability of the NFC suspension.					
36863677	12	24	from	sectors	1173:1179	arg1	interesting					1158:1168	interesting	1158:1168	interesting	1158:1168	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	12	24	from	sectors	1173:1179	arg1	application					1130:1140	the application	1126:1140	the application of mandacaru	1126:1153	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	5	25	theme	suspensions	450:460	arg1	homogeneity					400:410	Particle homogeneity	391:410	Particle homogeneity	391:410	Particle homogeneity, turbidity, and microstructure of the suspensions were evaluated.					
36863677	5	25	theme	suspensions	450:460	arg1	turbidity					413:421	turbidity	413:421	turbidity	413:421	Particle homogeneity, turbidity, and microstructure of the suspensions were evaluated.					
36863677	5	25	theme	suspensions	450:460	arg1	microstructure					428:441	microstructure	428:441	microstructure	428:441	Particle homogeneity, turbidity, and microstructure of the suspensions were evaluated.					
36863677	12	26	theme	composite	1248:1256	arg1	materials					1258:1266	composite materials	1248:1266	composite materials	1248:1266	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	3	27	theme	alkaline	245:252	arg1	treatment					254:262	alkaline treatment	245:262	alkaline treatment	245:262	The technique adopted includes alkaline treatment, bleaching, and grinding treatment.					
36863677	11	28	theme	material	1105:1112	arg1	stability					1057:1065	good thermal stability	1044:1065	good thermal stability	1044:1065	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	11	28	theme	material	1105:1112	arg1	properties					1087:1096	good mechanical properties	1071:1096	good mechanical properties	1071:1096	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	13	29	theme	innovative	1376:1385	arg1	material					1323:1330	this material	1318:1330	this material	1318:1330	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	13	29	theme	innovative	1376:1385	arg1	source					1387:1392	an attractive, facile, and innovative source	1349:1392	an attractive, facile, and innovative source for obtaining NFC	1349:1410	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	13	30	theme	attractive	1352:1361	arg1	material					1323:1330	this material	1318:1330	this material	1318:1330	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	13	30	theme	attractive	1352:1361	arg1	source					1387:1392	an attractive, facile, and innovative source	1349:1392	an attractive, facile, and innovative source for obtaining NFC	1349:1410	Given its score of 72 points on a quality index, this material was presented as an attractive, facile, and innovative source for obtaining NFC.					
36863677	12	31	from	interesting	1158:1168	arg1	packaging					1189:1197	packaging	1189:1197	packaging	1189:1197	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	12	31	from	interesting	1158:1168	arg1	materials					1258:1266	composite materials	1248:1266	composite materials	1248:1266	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	12	31	from	interesting	1158:1168	arg1	development					1221:1231	electronic device development	1203:1231	electronic device development	1203:1231	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	12	31	from	interesting	1158:1168	arg1	sectors					1173:1179	sectors	1173:1179	sectors such as packaging and electronic device development	1173:1231	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	9	32	theme	environmental	780:792	arg1	ESEM					824:827	ESEM	824:827	ESEM	824:827	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	9	32	theme	environmental	780:792	arg1	microscopy					812:821	environmental scanning electron microscopy	780:821	environmental scanning electron microscopy (ESEM)	780:828	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	2	33	dep	production	202:211	arg1	mandacaru					177:185	mandacaru	177:185	mandacaru	177:185	(mandacaru) for nanopaper production.					
36863677	0	34	theme	cellulose	48:56	arg1	cactus					10:15	cactus	10:15	cactus	10:15	Mandacaru cactus as a source of nanofibrillated cellulose for nanopaper production.					
36863677	0	34	theme	cellulose	48:56	arg1	source					22:27	a source	20:27	a source of nanofibrillated cellulose for nanopaper production	20:81	Mandacaru cactus as a source of nanofibrillated cellulose for nanopaper production.					
36863677	3	35	theme	grinding	280:287	arg1	treatment					289:297	grinding treatment	280:297	grinding treatment	280:297	The technique adopted includes alkaline treatment, bleaching, and grinding treatment.					
36863677	12	36	theme	electronic	1203:1212	arg1	development					1221:1231	electronic device development	1203:1231	electronic device development	1203:1231	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	2	37	theme	nanopaper	192:200	arg1	production					202:211	nanopaper production	192:211	nanopaper production	192:211	(mandacaru) for nanopaper production.					
36863677	1	38	theme	nanofibrillated	98:112	arg1	NFC					125:127	NFC	125:127	NFC	125:127	In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC.					
36863677	1	38	theme	nanofibrillated	98:112	arg1	cellulose					114:122	nanofibrillated cellulose	98:122	nanofibrillated cellulose (NFC)	98:128	In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC.					
36863677	0	39	theme	nanofibrillated	32:46	arg1	cellulose					48:56	nanofibrillated cellulose	32:56	nanofibrillated cellulose	32:56	Mandacaru cactus as a source of nanofibrillated cellulose for nanopaper production.					
36863677	11	40	theme	mechanical	996:1005	arg1	analysis					1007:1014	mechanical analysis	996:1014	mechanical analysis	996:1014	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	12	41	theme	device	1214:1219	arg1	development					1221:1231	electronic device development	1203:1231	electronic device development	1203:1231	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	8	42	theme	sedimentation	640:652	arg1	test					654:657	The sedimentation test	636:657	The sedimentation test	636:657	The sedimentation test and the zeta potential analyzed the stability of the NFC suspension.					
36863677	9	43	theme	electron	803:810	arg1	ESEM					824:827	ESEM	824:827	ESEM	824:827	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	9	43	theme	electron	803:810	arg1	microscopy					812:821	environmental scanning electron microscopy	780:821	environmental scanning electron microscopy (ESEM)	780:828	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	12	44	from	materials	1258:1266	arg1	interesting					1158:1168	interesting	1158:1168	interesting	1158:1168	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	11	45	theme	good	1044:1047	arg1	stability					1057:1065	good thermal stability	1044:1065	good thermal stability	1044:1065	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	11	46	used	used	1026:1029	arg2	analysis					977:984	Thermogravimetric analysis	959:984	Thermogravimetric analysis (TGA)	959:990	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	11	46	used	used	1026:1029	arg2	analysis					1007:1014	mechanical analysis	996:1014	mechanical analysis	996:1014	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	11	46	used	used	1026:1029	arg2	TGA					987:989	TGA	987:989	TGA	987:989	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
36863677	10	47	theme	diffraction	880:890	arg1	analysis					898:905	X-ray diffraction (XRD) analysis	874:905	X-ray diffraction (XRD) analysis	874:905	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	9	48	theme	scanning	794:801	arg1	ESEM					824:827	ESEM	824:827	ESEM	824:827	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	9	48	theme	scanning	794:801	arg1	microscopy					812:821	environmental scanning electron microscopy	780:821	environmental scanning electron microscopy (ESEM)	780:828	The morphological investigation was performed using environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM).					
36863677	10	49	theme	X-ray	874:878	arg1	XRD					893:895	XRD	893:895	XRD	893:895	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	10	49	theme	X-ray	874:878	arg1	diffraction					880:890	X-ray diffraction	874:890	X-ray diffraction (XRD) analysis	874:905	X-ray diffraction (XRD) analysis revealed that Mandacaru NFC has high crystallinity.					
36863677	6	50	theme	nanopapers	549:558	arg1	properties					531:540	the optical and physical-mechanical properties	495:540	the optical and physical-mechanical properties of the nanopapers	495:558	Correspondingly, the optical and physical-mechanical properties of the nanopapers were investigated.					
36863677	5	51	gly	homogeneity	400:410	arg1	suspensions					450:460	the suspensions	446:460	the suspensions	446:460	Particle homogeneity, turbidity, and microstructure of the suspensions were evaluated.					
36863677	12	52	theme	mandacaru	1145:1153	arg1	interesting					1158:1168	interesting	1158:1168	interesting	1158:1168	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	12	52	theme	mandacaru	1145:1153	arg1	application					1130:1140	the application	1126:1140	the application of mandacaru	1126:1153	Therefore, the application of mandacaru is interesting in sectors such as packaging and electronic device development, as well as in composite materials.					
36863677	8	53	theme	zeta	667:670	arg1	potential					672:680	the zeta potential	663:680	the zeta potential	663:680	The sedimentation test and the zeta potential analyzed the stability of the NFC suspension.					
36863677	11	54	theme	good	1071:1074	arg1	properties					1087:1096	good mechanical properties	1071:1096	good mechanical properties	1071:1096	Thermogravimetric analysis (TGA) and mechanical analysis were also used and revealed good thermal stability and good mechanical properties of the material.					
35843401	6	0	theme	properties	1236:1245	arg1	evolution					1202:1210	The evolution	1198:1210	The evolution of the melt rheological properties of the different compositions	1198:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	6	0	theme	properties	1236:1245	arg1	properties					1309:1318	the mechanical and optical properties	1282:1318	the mechanical and optical properties of the films with and without a short annealing treatment	1282:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	5	1	theme	nucleating	1049:1058	arg1	agents					1060:1065	the different nucleating agents	1035:1065	the different nucleating agents	1035:1065	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	2	2	theme	poly	511:514	arg1	poly					511:514	poly	511:514	poly(ethylene glycol) (PEG)	511:537	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	2	theme	poly	511:514	arg1	glycol					525:530	ethylene glycol	516:530	ethylene glycol	516:530	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	2	theme	poly	511:514	arg1	amount					501:506	a small amount	493:506	a small amount of poly(ethylene glycol) (PEG)	493:537	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	2	theme	poly	511:514	arg1	PEG					534:536	PEG	534:536	PEG	534:536	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	4	3	theme	crystallization	786:800	arg1	half-time					802:810	The crystallization half-time	782:810	The crystallization half-time	782:810	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	5	4	theme	highest	1110:1116	arg1	γp					1118:1119	the highest γp	1106:1119	the highest γp	1106:1119	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	4	5	theme	surface	877:883	arg1	properties					885:894	surface properties	877:894	surface properties	877:894	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	1	6	theme	several	200:206	arg1	NPs					232:234	NPs	232:234	NPs	232:234	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	6	theme	several	200:206	arg1	nanoparticles					217:229	several biobased nanoparticles	200:229	several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs),	200:437	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	6	7	theme	melt	1219:1222	arg1	properties					1236:1245	the melt rheological properties	1215:1245	the melt rheological properties of the different compositions	1215:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	1	8	theme	cellulose	299:307	arg1	nanofibrils					309:319	cellulose nanofibrils	299:319	cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs)	299:436	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	6	9	theme	short	1352:1356	arg1	treatment					1368:1376	a short annealing treatment	1350:1376	a short annealing treatment	1350:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	3	10	theme	secondary	753:761	arg1	theory					774:779	Avrami's and Lauritzen-Hoffman's secondary nucleation theory	720:779	Avrami's and Lauritzen-Hoffman's secondary nucleation theory	720:779	The nucleation efficiency was investigated by differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory.					
35843401	1	11	theme	biobased	208:215	arg1	NPs					232:234	NPs	232:234	NPs	232:234	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	11	theme	biobased	208:215	arg1	nanoparticles					217:229	several biobased nanoparticles	200:229	several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs),	200:437	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	5	12	with	nanofiller	1090:1099	arg1	γp					1118:1119	the highest γp	1106:1119	the highest γp	1106:1119	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	2	13	theme	small	495:499	arg1	poly					511:514	poly	511:514	poly(ethylene glycol) (PEG)	511:537	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	13	theme	small	495:499	arg1	glycol					525:530	ethylene glycol	516:530	ethylene glycol	516:530	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	13	theme	small	495:499	arg1	amount					501:506	a small amount	493:506	a small amount of poly(ethylene glycol) (PEG)	493:537	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	13	theme	small	495:499	arg1	PEG					534:536	PEG	534:536	PEG	534:536	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	5	14	theme	nucleating	1177:1186	arg1	aptitude					1188:1195	the most effective nucleating aptitude	1158:1195	the most effective nucleating aptitude	1158:1195	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	1	15	theme	nanoparticles	217:229	arg1	PLLA					191:194	PLLA	191:194	PLLA	191:194	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	15	theme	nanoparticles	217:229	arg1	poly-L-					169:175	poly-L-	169:175	poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs),	169:437	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	15	theme	nanoparticles	217:229	arg1	acid					184:187	lactic acid	177:187	lactic acid	177:187	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	4	16	dep	found	816:820	arg1	followed					957:964	followed	957:964	followed by ChNCs, SNCs and LCNFs	957:989	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	0	17	theme	rheological	81:91	arg1	agents					20:25	Biobased nucleation agents	0:25	Biobased nucleation agents for poly-L-(lactic acid)	0:50	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	17	theme	rheological	81:91	arg1	properties					108:117	rheological and mechanical properties	81:117	properties	108:117	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	1	18	theme	nucleating	145:154	arg1	aptitude					156:163	the nucleating aptitude	141:163	the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs),	141:437	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	0	19	theme	nucleation	9:18	arg1	agents					20:25	Biobased nucleation agents	0:25	Biobased nucleation agents for poly-L-(lactic acid)	0:50	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	19	theme	nucleation	9:18	arg1	properties					108:117	rheological and mechanical properties	81:117	properties	108:117	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	19	theme	nucleation	9:18	arg1	acid					46:49	lactic acid	39:49	lactic acid	39:49	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	6	20	theme	rheological	1224:1234	arg1	properties					1236:1245	the melt rheological properties	1215:1245	the melt rheological properties of the different compositions	1215:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	2	21	theme	ethylene	516:523	arg1	poly					511:514	poly	511:514	poly(ethylene glycol) (PEG)	511:537	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	2	21	theme	ethylene	516:523	arg1	glycol					525:530	ethylene glycol	516:530	ethylene glycol	516:530	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	1	22	theme	starch	395:400	arg1	nanocrystals					402:413	starch nanocrystals	395:413	starch nanocrystals (CNCs, ChNCs and SNCs)	395:436	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	2	23	theme	nanofiller	605:614	arg1	content					616:622	the same nanofiller content	596:622	the same nanofiller content of 1 wt%	596:631	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	0	24	theme	Biobased	0:7	arg1	agents					20:25	Biobased nucleation agents	0:25	Biobased nucleation agents for poly-L-(lactic acid)	0:50	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	24	theme	Biobased	0:7	arg1	properties					108:117	rheological and mechanical properties	81:117	properties	108:117	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	24	theme	Biobased	0:7	arg1	acid					46:49	lactic acid	39:49	lactic acid	39:49	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	6	25	theme	mechanical	1286:1295	arg1	properties					1309:1318	the mechanical and optical properties	1282:1318	the mechanical and optical properties of the films with and without a short annealing treatment	1282:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	5	26	theme	different	1039:1047	arg1	agents					1060:1065	the different nucleating agents	1035:1065	the different nucleating agents	1035:1065	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	2	27	theme	single	459:464	arg1	step					482:485	A single melt-processing step	457:485	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs	457:560	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	3	28	theme	scanning	693:700	arg1	calorimetry					702:712	differential scanning calorimetry	680:712	differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory	680:779	The nucleation efficiency was investigated by differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory.					
35843401	6	29	theme	films	1327:1331	arg1	evolution					1202:1210	The evolution	1198:1210	The evolution of the melt rheological properties of the different compositions	1198:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	6	29	theme	films	1327:1331	arg1	properties					1309:1318	the mechanical and optical properties	1282:1318	the mechanical and optical properties of the films with and without a short annealing treatment	1282:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	4	30	theme	lowest	917:922	arg1	time					924:927	the lowest time	913:927	the lowest time observed for CNFs and CNCs	913:954	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	4	31	theme	NPs	903:905	arg1	morphology					862:871	morphology	862:871	morphology	862:871	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	4	31	theme	NPs	903:905	arg1	properties					885:894	surface properties	877:894	surface properties	877:894	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	0	32	theme	mechanical	97:106	arg1	agents					20:25	Biobased nucleation agents	0:25	Biobased nucleation agents for poly-L-(lactic acid)	0:50	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	32	theme	mechanical	97:106	arg1	properties					108:117	rheological and mechanical properties	81:117	properties	108:117	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	5	33	theme	effective	1167:1175	arg1	aptitude					1188:1195	the most effective nucleating aptitude	1158:1195	the most effective nucleating aptitude	1158:1195	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	6	34	theme	annealing	1358:1366	arg1	treatment					1368:1376	a short annealing treatment	1350:1376	a short annealing treatment	1350:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	5	35	theme	agents	1060:1065	arg1	components					1021:1030	the surface energy components	1002:1030	the surface energy components of the different nucleating agents	1002:1065	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	0	36	from	Effect	54:59	arg1	crystallization					64:78	crystallization	64:78	crystallization	64:78	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	6	37	theme	optical	1301:1307	arg1	properties					1309:1318	the mechanical and optical properties	1282:1318	the mechanical and optical properties of the films with and without a short annealing treatment	1282:1376	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	2	38	theme	%	631:631	arg1	content					616:622	the same nanofiller content	596:622	the same nanofiller content of 1 wt%	596:631	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	1	39	theme	lactic	177:182	arg1	poly-L-					169:175	poly-L-	169:175	poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs),	169:437	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	39	theme	lactic	177:182	arg1	acid					184:187	lactic acid	177:187	lactic acid	177:187	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	2	40	with	films	585:589	arg1	content					616:622	the same nanofiller content	596:622	the same nanofiller content of 1 wt%	596:631	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	1	41	theme	different	242:250	arg1	morphologies					252:263	different morphologies	242:263	different morphologies	242:263	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	41	theme	different	242:250	arg1	nanofibrils					309:319	cellulose nanofibrils	299:319	cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs)	299:436	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	6	42	theme	compositions	1264:1275	arg1	properties					1236:1245	the melt rheological properties	1215:1245	the melt rheological properties of the different compositions	1215:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	3	43	theme	nucleation	638:647	arg1	efficiency					649:658	The nucleation efficiency	634:658	The nucleation efficiency	634:658	The nucleation efficiency was investigated by differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory.					
35843401	1	44	with	nanoparticles	217:229	arg1	morphologies					252:263	different morphologies	242:263	different morphologies	242:263	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	44	with	nanoparticles	217:229	arg1	properties					277:286	surface properties	269:286	surface properties	269:286	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	44	with	nanoparticles	217:229	arg1	nanofibrils					309:319	cellulose nanofibrils	299:319	cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs)	299:436	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	0	45	theme	lactic	39:44	arg1	agents					20:25	Biobased nucleation agents	0:25	Biobased nucleation agents for poly-L-(lactic acid)	0:50	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	0	45	theme	lactic	39:44	arg1	acid					46:49	lactic acid	39:49	lactic acid	39:49	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	5	46	theme	surface	1006:1012	arg1	components					1021:1030	the surface energy components	1002:1030	the surface energy components of the different nucleating agents	1002:1065	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	1	47	theme	surface	269:275	arg1	properties					277:286	surface properties	269:286	surface properties	269:286	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	47	theme	surface	269:275	arg1	nanofibrils					309:319	cellulose nanofibrils	299:319	cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs)	299:436	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	5	48	contain	had	1121:1123	arg2	t1/2					1136:1139	the lowest t1/2	1125:1139	the lowest t1/2	1125:1139	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	5	48	contain	had	1121:1123	arg1	nanofiller					1090:1099	the nanofiller	1086:1099	the nanofiller with the highest γp	1086:1119	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	5	49	theme	lowest	1129:1134	arg1	t1/2					1136:1139	the lowest t1/2	1125:1139	the lowest t1/2	1125:1139	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35843401	2	50	theme	melt-processing	466:480	arg1	step					482:485	A single melt-processing step	457:485	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs	457:560	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	0	51	dep	agents	20:25	arg1	Effect					54:59	Effect	54:59	Effect on crystallization	54:78	Biobased nucleation agents for poly-L-(lactic acid) - Effect on crystallization, rheological and mechanical properties.					
35843401	2	52	theme	same	600:603	arg1	content					616:622	the same nanofiller content	596:622	the same nanofiller content of 1 wt%	596:631	A single melt-processing step using a small amount of poly(ethylene glycol) (PEG) as carrier for the NPs was adopted to prepare films with the same nanofiller content of 1 wt%.					
35843401	4	53	dep	morphology	862:871	arg1	the					858:860	the	858:860	the	858:860	The crystallization half-time was found to change considerably according to the morphology and surface properties of the NPs, with the lowest time observed for CNFs and CNCs, followed by ChNCs, SNCs and LCNFs.					
35843401	3	54	theme	nucleation	763:772	arg1	theory					774:779	Avrami's and Lauritzen-Hoffman's secondary nucleation theory	720:779	Avrami's and Lauritzen-Hoffman's secondary nucleation theory	720:779	The nucleation efficiency was investigated by differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory.					
35843401	6	55	theme	different	1254:1262	arg1	compositions					1264:1275	the different compositions	1250:1275	the different compositions	1250:1275	The evolution of the melt rheological properties of the different compositions, and the mechanical and optical properties of the films with and without a short annealing treatment were also studied.					
35843401	1	56	dep	lignin	338:343	arg1	LCNFs					346:350	LCNFs	346:350	LCNFs	346:350	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	56	dep	lignin	338:343	arg1	CNFs					356:359	CNFs	356:359	CNFs	356:359	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	3	57	theme	differential	680:691	arg1	calorimetry					702:712	differential scanning calorimetry	680:712	differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory	680:779	The nucleation efficiency was investigated by differential scanning calorimetry using Avrami's and Lauritzen-Hoffman's secondary nucleation theory.					
35843401	1	58	theme	present	127:133	arg1	work					135:138	the present work	123:138	the present work	123:138	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	59	dep	nanocrystals	402:413	arg1	ChNCs					422:426	ChNCs	422:426	ChNCs	422:426	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	59	dep	nanocrystals	402:413	arg1	CNCs					416:419	CNCs	416:419	CNCs	416:419	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	1	59	dep	nanocrystals	402:413	arg1	SNCs					432:435	SNCs	432:435	SNCs	432:435	In the present work, the nucleating aptitude for poly-L-(lactic acid) (PLLA) of several biobased nanoparticles (NPs) with different morphologies and surface properties, including cellulose nanofibrils with and without lignin (LCNFs and CNFs) as well as cellulose, chitin and starch nanocrystals (CNCs, ChNCs and SNCs), was investigated.					
35843401	5	60	theme	energy	1014:1019	arg1	components					1021:1030	the surface energy components	1002:1030	the surface energy components of the different nucleating agents	1002:1065	Comparing the surface energy components of the different nucleating agents, it was found that the nanofiller with the highest γp had the lowest t1/2 and demonstrated the most effective nucleating aptitude.					
35753382	2	0	dep	polymers	456:463	arg1	dextran					549:555	dextran	549:555	dextran	549:555	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	0	dep	polymers	456:463	arg1	polyvinylpyrrolidone					485:504	polyvinylpyrrolidone	485:504	polyvinylpyrrolidone	485:504	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	0	dep	polymers	456:463	arg1	alcohol					476:482	polyvinyl alcohol	466:482	polyvinyl alcohol	466:482	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	0	dep	polymers	456:463	arg1	starch					541:546	hydroxyethyl starch	528:546	hydroxyethyl starch	528:546	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	0	dep	polymers	456:463	arg1	glycol					520:525	polyethylene glycol	507:525	polyethylene glycol	507:525	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	10	1	theme	media	1917:1921	arg1	toxicity					1888:1895	the toxicity	1884:1895	the toxicity of serum-/xeno-free media	1884:1921	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	5	2	theme	thermomechanical	1173:1188	arg1	analysis					1190:1197	thermomechanical analysis	1173:1197	thermomechanical analysis (TMA)	1173:1203	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	5	2	theme	thermomechanical	1173:1188	arg1	TMA					1200:1202	TMA	1200:1202	TMA	1200:1202	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	6	3	theme	ice	1287:1289	arg1	ice					1287:1289	ice	1287:1289	ice	1287:1289	The results showed that the medium based on Dex40 did not decrease the amount of ice formed.					
35753382	6	3	theme	ice	1287:1289	arg1	amount					1277:1282	the amount	1273:1282	the amount of ice formed	1273:1296	The results showed that the medium based on Dex40 did not decrease the amount of ice formed.					
35753382	5	4	theme	serum-/xeno-free	1032:1047	arg1	medium					1049:1054	this serum-/xeno-free medium	1027:1054	this serum-/xeno-free medium	1027:1054	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	3	5	from	dextran	755:761	arg1	course					698:703	the course	694:703	the course of this study	694:717	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	8	6	theme	cell-damaging	1406:1418	arg1	recrystallization					1481:1497	recrystallization	1481:1497	recrystallization of NaCl	1481:1505	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	6	theme	cell-damaging	1406:1418	arg1	crystallization/melting					1456:1478	eutectic crystallization/melting	1447:1478	eutectic crystallization/melting	1447:1478	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	6	theme	cell-damaging	1406:1418	arg1	processes					1429:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	6	theme	cell-damaging	1406:1418	arg1	derivatives					1520:1530	Me2SO derivatives	1514:1530	Me2SO derivatives	1514:1530	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	0	7	theme	dimethyl	98:105	arg1	sulfoxide					107:115	dimethyl sulfoxide	98:115	dimethyl sulfoxide	98:115	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	5	8	theme	medium	1049:1054	arg1	action					1017:1022	the cryoprotective action	998:1022	the cryoprotective action of this serum-/xeno-free medium	998:1054	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	2	9	theme	polyvinyl	466:474	arg1	dextran					549:555	dextran	549:555	dextran	549:555	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	9	theme	polyvinyl	466:474	arg1	polyvinylpyrrolidone					485:504	polyvinylpyrrolidone	485:504	polyvinylpyrrolidone	485:504	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	9	theme	polyvinyl	466:474	arg1	alcohol					476:482	polyvinyl alcohol	466:482	polyvinyl alcohol	466:482	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	9	theme	polyvinyl	466:474	arg1	starch					541:546	hydroxyethyl starch	528:546	hydroxyethyl starch	528:546	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	9	theme	polyvinyl	466:474	arg1	glycol					520:525	polyethylene glycol	507:525	polyethylene glycol	507:525	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	5	10	with	comparison	1076:1085	arg1	serum					1092:1096	serum	1092:1096	serum	1092:1096	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	5	10	with	comparison	1076:1085	arg1	media					1120:1124	albumin-containing media	1101:1124	albumin-containing media	1101:1124	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	7	11	theme	other	1325:1329	arg1	separation					1337:1346	other phase separation	1325:1346	other phase separation	1325:1346	However, it could undergo other phase separation and phase transformation to form glassy states.					
35753382	5	12	theme	differential	1129:1140	arg1	DSC					1164:1166	DSC	1164:1166	DSC	1164:1166	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	5	12	theme	differential	1129:1140	arg1	calorimetry					1151:1161	differential scanning calorimetry	1129:1161	differential scanning calorimetry (DSC)	1129:1167	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	4	13	theme	end	873:875	arg1	temperatures					877:888	different end temperatures	863:888	different end temperatures (-30, -50, -50 and -196 °C)	863:916	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	7	14	theme	phase	1352:1356	arg1	transformation					1358:1371	phase transformation	1352:1371	phase transformation	1352:1371	However, it could undergo other phase separation and phase transformation to form glassy states.					
35753382	2	15	theme	cells	595:599	arg1	cryopreservation					562:577	cryopreservation	562:577	cryopreservation of interstitial cells (ICs) of rat testis	562:619	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	7	16	theme	phase	1331:1335	arg1	separation					1337:1346	other phase separation	1325:1346	other phase separation	1325:1346	However, it could undergo other phase separation and phase transformation to form glassy states.					
35753382	5	17	theme	scanning	1142:1149	arg1	DSC					1164:1166	DSC	1164:1166	DSC	1164:1166	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	5	17	theme	scanning	1142:1149	arg1	calorimetry					1151:1161	differential scanning calorimetry	1129:1161	differential scanning calorimetry (DSC)	1129:1167	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	9	18	theme	cell	1709:1712	arg1	survival					1714:1721	cell survival	1709:1721	cell survival	1709:1721	This was in good correlation with indicators of cell survival.					
35753382	2	19	theme	polyethylene	507:518	arg1	glycol					520:525	polyethylene glycol	507:525	polyethylene glycol	507:525	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	19	theme	polyethylene	507:518	arg1	alcohol					476:482	polyvinyl alcohol	466:482	polyvinyl alcohol	466:482	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	5	20	theme	cryoprotective	1002:1015	arg1	action					1017:1022	the cryoprotective action	998:1022	the cryoprotective action of this serum-/xeno-free medium	998:1054	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	1	21	from	difficulty	287:296	arg1	sterilization					301:313	sterilization	301:313	sterilization	301:313	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	10	22	theme	serum-/xeno-free	1900:1915	arg1	media					1917:1921	serum-/xeno-free media	1900:1921	serum-/xeno-free media	1900:1921	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	4	23	theme	different	863:871	arg1	temperatures					877:888	different end temperatures	863:888	different end temperatures (-30, -50, -50 and -196 °C)	863:916	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	2	24	theme	combinations	379:390	arg1	use					372:374	the use	368:374	the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis	368:619	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	25	theme	rat	610:612	arg1	testis					614:619	rat testis	610:619	rat testis	610:619	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	26	theme	cryoprotection	654:667	arg1	mechanism					641:649	the mechanism	637:649	the mechanism of cryoprotection of such compositions	637:688	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	8	27	theme	Dex40	1642:1646	arg1	media					1654:1658	the Dex40 based media	1638:1658	the Dex40 based media	1638:1658	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	0	28	theme	Phase	0:4	arg1	transitions					6:16	Phase transitions	0:16	Phase transitions	0:16	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	1	29	theme	composition	271:281	arg1	difficulty					287:296	difficulty	287:296	difficulty in sterilization	287:313	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	1	29	theme	composition	271:281	arg1	instability					256:266	instability	256:266	instability of composition	256:281	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	1	29	theme	composition	271:281	arg1	contamination					241:253	probable contamination	232:253	probable contamination	232:253	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	3	30	theme	best	724:727	arg1	combination					729:739	the best combination	720:739	the best combination	720:739	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	3	30	theme	best	724:727	arg1	dextran					755:761	100 mg/ml dextran	745:761	100 mg/ml dextran (M.m. 40 kDa) (Dex40)	745:783	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	1	31	from	instability	256:266	arg1	sterilization					301:313	sterilization	301:313	sterilization	301:313	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	8	32	theme	NaCl	1502:1505	arg1	recrystallization					1481:1497	recrystallization	1481:1497	recrystallization of NaCl	1481:1505	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	2	33	theme	agent	423:427	arg1	combinations					379:390	combinations	379:390	combinations of a permeating cryoprotective agent (Me2SO)	379:435	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	33	theme	agent	423:427	arg1	polymers					456:463	non-permeating polymers	441:463	non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran)	441:556	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	4	34	theme	temperature	937:947	arg1	intervals					949:957	intervals	949:957	intervals	949:957	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	3	35	theme	study	713:717	arg1	course					698:703	the course	694:703	the course of this study	694:717	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	10	36	theme	lower	1786:1790	arg1	0.7 M					1808:1812	0.7 M	1808:1812	0.7 M	1808:1812	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	10	36	theme	lower	1786:1790	arg1	concentrations					1792:1805	lower concentrations	1786:1805	lower concentrations (0.7 M)	1786:1813	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	2	37	theme	cryoprotective	408:421	arg1	Me2SO					430:434	Me2SO	430:434	Me2SO	430:434	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	37	theme	cryoprotective	408:421	arg1	agent					423:427	a permeating cryoprotective agent	395:427	a permeating cryoprotective agent (Me2SO)	395:435	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	0	38	theme	cryoprotection	36:49	arg1	mechanisms					22:31	mechanisms	22:31	mechanisms	22:31	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	0	38	theme	cryoprotection	36:49	arg1	transitions					6:16	Phase transitions	0:16	Phase transitions	0:16	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	5	39	theme	albumin-containing	1101:1118	arg1	media					1120:1124	albumin-containing media	1101:1124	albumin-containing media	1101:1124	Then, the cryoprotective action of this serum-/xeno-free medium was investigated in comparison with serum or albumin-containing media by differential scanning calorimetry (DSC) and thermomechanical analysis (TMA).					
35753382	1	40	from	contamination	241:253	arg1	sterilization					301:313	sterilization	301:313	sterilization	301:313	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	2	41	theme	permeating	397:406	arg1	Me2SO					430:434	Me2SO	430:434	Me2SO	430:434	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	41	theme	permeating	397:406	arg1	agent					423:427	a permeating cryoprotective agent	395:427	a permeating cryoprotective agent (Me2SO)	395:435	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	3	42	theme	100 mg/ml	745:753	arg1	40 kDa					769:774	40 kDa	769:774	40 kDa	769:774	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	3	42	theme	100 mg/ml	745:753	arg1	Dex40					778:782	Dex40	778:782	Dex40	778:782	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	3	42	theme	100 mg/ml	745:753	arg1	combination					729:739	the best combination	720:739	the best combination	720:739	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	3	42	theme	100 mg/ml	745:753	arg1	dextran					755:761	100 mg/ml dextran	745:761	100 mg/ml dextran (M.m. 40 kDa) (Dex40)	745:783	In the course of this study, the best combination was 100 mg/ml dextran (M.m. 40 kDa) (Dex40) with 0.7 M Me2SO in Ham's F12.					
35753382	9	43	theme	good	1673:1676	arg1	correlation					1678:1688	good correlation	1673:1688	good correlation with indicators of cell survival	1673:1721	This was in good correlation with indicators of cell survival.					
35753382	9	44	theme	survival	1714:1721	arg1	indicators					1695:1704	indicators	1695:1704	indicators of cell survival	1695:1721	This was in good correlation with indicators of cell survival.					
35753382	2	45	theme	polymers	456:463	arg1	use					372:374	the use	368:374	the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis	368:619	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	46	theme	hydroxyethyl	528:539	arg1	starch					541:546	hydroxyethyl starch	528:546	hydroxyethyl starch	528:546	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	46	theme	hydroxyethyl	528:539	arg1	alcohol					476:482	polyvinyl alcohol	466:482	polyvinyl alcohol	466:482	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	47	theme	interstitial	582:593	arg1	ICs					602:604	ICs	602:604	ICs	602:604	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	47	theme	interstitial	582:593	arg1	cells					595:599	interstitial cells	582:599	interstitial cells (ICs)	582:605	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	0	48	theme	media	71:75	arg1	cryoprotection					36:49	cryoprotection	36:49	cryoprotection of serum-/xeno-free media	36:75	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	8	49	theme	eutectic	1447:1454	arg1	crystallization/melting					1456:1478	eutectic crystallization/melting	1447:1478	eutectic crystallization/melting	1447:1478	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	2	50	theme	research	339:346	arg1	objectives					320:329	The objectives	316:329	The objectives of this research	316:346	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	51	theme	non-permeating	441:454	arg1	polymers					456:463	non-permeating polymers	441:463	non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran)	441:556	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	8	52	theme	Potential	1396:1404	arg1	recrystallization					1481:1497	recrystallization	1481:1497	recrystallization of NaCl	1481:1505	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	52	theme	Potential	1396:1404	arg1	crystallization/melting					1456:1478	eutectic crystallization/melting	1447:1478	eutectic crystallization/melting	1447:1478	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	52	theme	Potential	1396:1404	arg1	processes					1429:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	52	theme	Potential	1396:1404	arg1	derivatives					1520:1530	Me2SO derivatives	1514:1530	Me2SO derivatives	1514:1530	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	2	53	theme	testis	614:619	arg1	cryopreservation					562:577	cryopreservation	562:577	cryopreservation of interstitial cells (ICs) of rat testis	562:619	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	2	54	theme	compositions	677:688	arg1	cryoprotection					654:667	cryoprotection	654:667	cryoprotection of such compositions	654:688	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	10	55	from	Me2SO	1777:1781	arg1	0.7 M					1808:1812	0.7 M	1808:1812	0.7 M	1808:1812	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	10	55	from	Me2SO	1777:1781	arg1	concentrations					1792:1805	lower concentrations	1786:1805	lower concentrations (0.7 M)	1786:1813	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	8	56	theme	specific	1585:1592	arg1	intervals					1606:1614	specific temperature intervals	1585:1614	specific temperature intervals	1585:1614	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	57	theme	Me2SO	1514:1518	arg1	derivatives					1520:1530	Me2SO derivatives	1514:1530	Me2SO derivatives	1514:1530	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	10	58	theme	serum-containing	1833:1848	arg1	1.4 M					1857:1861	1.4 M	1857:1861	1.4 M	1857:1861	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	10	58	theme	serum-containing	1833:1848	arg1	media					1850:1854	serum-containing media	1833:1854	serum-containing media (1.4 M)	1833:1862	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	9	59	with	correlation	1678:1688	arg1	indicators					1695:1704	indicators	1695:1704	indicators of cell survival	1695:1721	This was in good correlation with indicators of cell survival.					
35753382	2	60	theme	such	672:675	arg1	compositions					677:688	such compositions	672:688	such compositions	672:688	The objectives of this research were to investigate the use of combinations of a permeating cryoprotective agent (Me2SO) and non-permeating polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, hydroxyethyl starch, dextran) for cryopreservation of interstitial cells (ICs) of rat testis, and to propose the mechanism of cryoprotection of such compositions.					
35753382	4	61	theme	IC	983:984	arg1	loss					986:989	the IC loss	979:989	the IC loss	979:989	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	10	62	theme	Dex40	1757:1761	arg1	application					1742:1752	the application	1738:1752	the application of Dex40	1738:1761	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	1	63	theme	serum-/xeno-free	137:152	arg1	media					154:158	serum-/xeno-free media	137:158	serum-/xeno-free media	137:158	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	4	64	dep	temperatures	877:888	arg1	-196 °C					909:915	-196 °C	909:915	-196 °C	909:915	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	4	64	dep	temperatures	877:888	arg1	-50					901:903	-50	901:903	-50	901:903	The ICs were additionally cooled and warmed to different end temperatures (-30, -50, -50 and -196 °C) to determine which temperature intervals contributed most to the IC loss.					
35753382	8	65	theme	based	1648:1652	arg1	media					1654:1658	the Dex40 based media	1638:1658	the Dex40 based media	1638:1658	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	66	theme	physical	1420:1427	arg1	recrystallization					1481:1497	recrystallization	1481:1497	recrystallization of NaCl	1481:1505	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	66	theme	physical	1420:1427	arg1	crystallization/melting					1456:1478	eutectic crystallization/melting	1447:1478	eutectic crystallization/melting	1447:1478	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	66	theme	physical	1420:1427	arg1	processes					1429:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	66	theme	physical	1420:1427	arg1	derivatives					1520:1530	Me2SO derivatives	1514:1530	Me2SO derivatives	1514:1530	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	67	located	observed	1626:1633	arg2	derivatives					1520:1530	Me2SO derivatives	1514:1530	Me2SO derivatives	1514:1530	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	67	located	observed	1626:1633	arg2	crystallization/melting					1456:1478	eutectic crystallization/melting	1447:1478	eutectic crystallization/melting	1447:1478	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	67	located	observed	1626:1633	arg2	processes					1429:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes	1396:1437	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	67	located	observed	1626:1633	arg1	media					1654:1658	the Dex40 based media	1638:1658	the Dex40 based media	1638:1658	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	67	located	observed	1626:1633	arg2	recrystallization					1481:1497	recrystallization	1481:1497	recrystallization of NaCl	1481:1505	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	1	68	theme	media	154:158	arg1	development					122:132	The development	118:132	The development of serum-/xeno-free media	118:158	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
35753382	8	69	theme	temperature	1594:1604	arg1	intervals					1606:1614	specific temperature intervals	1585:1614	specific temperature intervals	1585:1614	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	70	theme	serum-containing	1542:1557	arg1	media					1559:1563	serum-containing media	1542:1563	serum-containing media	1542:1563	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	0	71	theme	serum-/xeno-free	54:69	arg1	media					71:75	serum-/xeno-free media	54:75	serum-/xeno-free media	54:75	Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide.					
35753382	7	72	theme	glassy	1381:1386	arg1	states					1388:1393	glassy states	1381:1393	glassy states	1381:1393	However, it could undergo other phase separation and phase transformation to form glassy states.					
35753382	8	73	dep	processes	1429:1437	arg1	taking					1569:1574	taking	1569:1574	taking place in specific temperature intervals	1569:1614	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	8	73	dep	processes	1429:1437	arg1	found					1533:1537	found	1533:1537	found in serum-containing media	1533:1563	Potential cell-damaging physical processes such as eutectic crystallization/melting, recrystallization of NaCl and/or Me2SO derivatives, found in serum-containing media and taking place in specific temperature intervals, were not observed in the Dex40 based media.					
35753382	10	74	theme	using	1771:1775	arg1	Me2SO					1777:1781	using Me2SO	1771:1781	using Me2SO in lower concentrations (0.7 M)	1771:1813	Additionally, the application of Dex40 allowed using Me2SO in lower concentrations (0.7 M) than required for serum-containing media (1.4 M), which may decrease the toxicity of serum-/xeno-free media.					
35753382	1	75	theme	probable	232:239	arg1	contamination					241:253	probable contamination	232:253	probable contamination	232:253	The development of serum-/xeno-free media may help avoid the drawbacks of using serum and its components, such as probable contamination, instability of composition, or difficulty in sterilization.					
36991224	4	0	theme	absorption	438:447	arg1	wavelength					449:458	The maximum absorption wavelength	426:458	The maximum absorption wavelength of the composite film	426:480	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	9	1	theme	acid	1110:1113	arg1	content					1115:1121	ascorbic acid content	1101:1121	ascorbic acid content in dates	1101:1130	In the meantime, the fall of ascorbic acid content in dates was postponed, and E. coli survivability was increased.					
36991224	5	2	theme	absorption	563:572	arg1	dependent					617:625	dependent	617:625	dependent	617:625	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	5	2	theme	absorption	563:572	arg1	intensity					574:582	the UV absorption intensity	556:582	the UV absorption intensity of the composite film	556:604	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	7	3	theme	characteristics	902:916	arg1	measurement					812:822	the measurement	808:822	the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics	808:916	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	0	4	theme	mycosporine-like	99:114	arg1	acids					122:126	mycosporine-like amino acids	99:126	mycosporine-like amino acids	99:126	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	6	5	theme	storage	724:730	arg1	period					732:737	the 7 days storage period	713:737	the 7 days storage period	713:737	The composite film exhibited excellent stability during the 7 days storage period.					
36991224	5	6	theme	composite	591:599	arg1	film					601:604	the composite film	587:604	the composite film	587:604	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	10	7	theme	high	1278:1281	arg1	potential					1283:1291	a high potential	1276:1291	a high potential for usage in food packaging materials	1276:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	2	8	from	haitanensis	295:305	arg1	extraction					257:266	the extraction	253:266	the extraction of MAAs from Dried pyropia haitanensis	253:305	RESULTS In this study, the extraction of MAAs from Dried pyropia haitanensis was obtained.					
36991224	4	9	theme	MAAs	528:531	arg1	solution					533:540	MAAs solution	528:540	MAAs solution	528:540	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	5	10	theme	film	601:604	arg1	dependent					617:625	dependent	617:625	dependent	617:625	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	5	10	theme	film	601:604	arg1	intensity					574:582	the UV absorption intensity	556:582	the UV absorption intensity of the composite film	556:604	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	9	11	theme	ascorbic	1101:1108	arg1	acid					1110:1113	ascorbic acid	1101:1113	ascorbic acid content in dates	1101:1130	In the meantime, the fall of ascorbic acid content in dates was postponed, and E. coli survivability was increased.					
36991224	2	12	theme	MAAs	271:274	arg1	extraction					257:266	the extraction	253:266	the extraction of MAAs from Dried pyropia haitanensis	253:305	RESULTS In this study, the extraction of MAAs from Dried pyropia haitanensis was obtained.					
36991224	8	13	theme	actual	939:944	arg1	investigation					961:973	the actual anti-UV effect investigation	935:973	the actual anti-UV effect investigation	935:973	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	8	14	theme	value	1001:1005	arg1	increase					980:987	the increase	976:987	the increase of peroxide value and an acid value of grease under FOM film coverage	976:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	7	15	theme	visual	895:900	arg1	characteristics					902:916	visual characteristics	895:916	visual characteristics	895:916	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	7	16	theme	water	842:846	arg1	rate					867:870	water vapor transmission rate	842:870	water vapor transmission rate	842:870	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	0	17	theme	amino	116:120	arg1	acids					122:126	mycosporine-like amino acids	99:126	mycosporine-like amino acids	99:126	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	4	18	theme	maximum	430:436	arg1	wavelength					449:458	The maximum absorption wavelength	426:458	The maximum absorption wavelength of the composite film	426:480	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	5	19	theme	UV	560:561	arg1	dependent					617:625	dependent	617:625	dependent	617:625	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	5	19	theme	UV	560:561	arg1	intensity					574:582	the UV absorption intensity	556:582	the UV absorption intensity of the composite film	556:604	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	7	20	theme	transmission	877:888	arg1	measurement					812:822	the measurement	808:822	the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics	808:916	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	3	21	with	embedded	377:384	arg1	MAAs					391:394	MAAs	391:394	MAAs (0-0.3% w/w)	391:407	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	3	21	with	embedded	377:384	arg1	%					402:402	0-0.3% w/w	397:406	0-0.3% w/w	397:406	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	3	22	dep	films	371:375	arg1	embedded					377:384	embedded	377:384	embedded	377:384	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	0	23	theme	starch	73:78	arg1	film					80:83	starch film	73:83	starch film	73:83	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	7	24	theme	physicochemical	744:758	arg1	features					760:767	The physicochemical features	740:767	The physicochemical features of composite film	740:785	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	6	25	theme	7 days	717:722	arg1	period					732:737	the 7 days storage period	713:737	the 7 days storage period	713:737	The composite film exhibited excellent stability during the 7 days storage period.					
36991224	7	26	theme	film	782:785	arg1	features					760:767	The physicochemical features	740:767	The physicochemical features of composite film	740:785	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	0	27	theme	UV-resistance	19:31	arg1	capability					33:42	the UV-resistance capability	15:42	the UV-resistance capability of the fish	15:54	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	8	28	theme	value	1019:1023	arg1	increase					980:987	the increase	976:987	the increase of peroxide value and an acid value of grease under FOM film coverage	976:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	7	29	theme	oil	873:875	arg1	transmission					877:888	oil transmission	873:888	oil transmission	873:888	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	2	30	theme	pyropia	287:293	arg1	haitanensis					295:305	Dried pyropia haitanensis	281:305	Dried pyropia haitanensis	281:305	RESULTS In this study, the extraction of MAAs from Dried pyropia haitanensis was obtained.					
36991224	10	31	theme	food	1306:1309	arg1	materials					1321:1329	food packaging materials	1306:1329	food packaging materials	1306:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	1	32	theme	strongest	193:201	arg1	MAAs					140:143	BACKGROUND MAAs	129:143	BACKGROUND MAAs (mycosporine-like amino acids)	129:174	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	32	theme	strongest	193:201	arg1	guardians					209:217	the strongest solar guardians	189:217	the strongest solar guardians in nature	189:227	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	3	33	theme	starch	351:356	arg1	films					371:375	Fish gelatin(FG) and oxidized starch(OS)composite films	321:375	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w)	321:407	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	8	34	theme	acid	1014:1017	arg1	value					1019:1023	an acid value	1011:1023	an acid value of grease under FOM film coverage	1011:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	10	35	theme	packaging	1311:1319	arg1	materials					1321:1329	food packaging materials	1306:1329	food packaging materials	1306:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	2	36	theme	Dried	281:285	arg1	haitanensis					295:305	Dried pyropia haitanensis	281:305	Dried pyropia haitanensis	281:305	RESULTS In this study, the extraction of MAAs from Dried pyropia haitanensis was obtained.					
36991224	1	37	theme	solar	203:207	arg1	MAAs					140:143	BACKGROUND MAAs	129:143	BACKGROUND MAAs (mycosporine-like amino acids)	129:174	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	37	theme	solar	203:207	arg1	guardians					209:217	the strongest solar guardians	189:217	the strongest solar guardians in nature	189:227	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	8	38	theme	grease	1028:1033	arg1	value					1001:1005	peroxide value	992:1005	peroxide value	992:1005	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	8	38	theme	grease	1028:1033	arg1	value					1019:1023	an acid value	1011:1023	an acid value of grease under FOM film coverage	1011:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	7	39	theme	composite	772:780	arg1	film					782:785	composite film	772:785	composite film	772:785	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	0	40	theme	capability	33:42	arg1	Improvement					0:10	Improvement	0:10	Improvement of the UV-resistance capability of the fish	0:54	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	4	41	theme	film	477:480	arg1	wavelength					449:458	The maximum absorption wavelength	426:458	The maximum absorption wavelength of the composite film	426:480	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	5	42	theme	MAAs	651:654	arg1	concentration					634:646	the concentration	630:646	the concentration of MAAs	630:654	Furthermore, the UV absorption intensity of the composite film was highly dependent on the concentration of MAAs.					
36991224	3	43	theme	oxidized	342:349	arg1	OS					358:359	OS	358:359	OS	358:359	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	3	43	theme	oxidized	342:349	arg1	starch					351:356	oxidized starch	342:356	oxidized starch(OS)	342:360	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	1	44	from	guardians	209:217	arg1	nature					222:227	nature	222:227	nature	222:227	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	3	45	theme	w/w	404:406	arg1	MAAs					391:394	MAAs	391:394	MAAs (0-0.3% w/w)	391:407	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	3	45	theme	w/w	404:406	arg1	%					402:402	0-0.3% w/w	397:406	0-0.3% w/w	397:406	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	0	46	theme	fish	51:54	arg1	capability					33:42	the UV-resistance capability	15:42	the UV-resistance capability of the fish	15:54	Improvement of the UV-resistance capability of the fish gelatin-oxidized starch film via inserting mycosporine-like amino acids.					
36991224	4	47	theme	composite	467:475	arg1	film					477:480	the composite film	463:480	the composite film	463:480	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	8	48	theme	FOM	1041:1043	arg1	coverage					1050:1057	FOM film coverage	1041:1057	FOM film coverage	1041:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	9	49	theme	E.	1151:1152	arg1	survivability					1159:1171	E. coli survivability	1151:1171	E. coli survivability	1151:1171	In the meantime, the fall of ascorbic acid content in dates was postponed, and E. coli survivability was increased.					
36991224	10	50	dep	suggest	1211:1217	arg1	has					1272:1274	has	1272:1274	suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials	1211:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	10	51	from	usage	1297:1301	arg1	materials					1321:1329	food packaging materials	1306:1329	food packaging materials	1306:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	3	52	theme	composite	361:369	arg1	films					371:375	Fish gelatin(FG) and oxidized starch(OS)composite films	321:375	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w)	321:407	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	9	53	theme	coli	1154:1157	arg1	survivability					1159:1171	E. coli survivability	1151:1171	E. coli survivability	1151:1171	In the meantime, the fall of ascorbic acid content in dates was postponed, and E. coli survivability was increased.					
36991224	8	54	theme	peroxide	992:999	arg1	value					1001:1005	peroxide value	992:1005	peroxide value	992:1005	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	6	55	theme	excellent	686:694	arg1	stability					696:704	excellent stability	686:704	excellent stability	686:704	The composite film exhibited excellent stability during the 7 days storage period.					
36991224	1	56	theme	BACKGROUND	129:138	arg1	MAAs					140:143	BACKGROUND MAAs	129:143	BACKGROUND MAAs (mycosporine-like amino acids)	129:174	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	56	theme	BACKGROUND	129:138	arg1	guardians					209:217	the strongest solar guardians	189:217	the strongest solar guardians in nature	189:227	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	56	theme	BACKGROUND	129:138	arg1	acids					169:173	mycosporine-like amino acids	146:173	mycosporine-like amino acids	146:173	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	7	57	theme	transmission	854:865	arg1	rate					867:870	water vapor transmission rate	842:870	water vapor transmission rate	842:870	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	8	58	theme	effect	954:959	arg1	investigation					961:973	the actual anti-UV effect investigation	935:973	the actual anti-UV effect investigation	935:973	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	10	59	with	film	1227:1230	arg1	anti-ultraviolet					1255:1270	anti-ultraviolet	1255:1270	anti-ultraviolet	1255:1270	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	10	59	with	film	1227:1230	arg1	biodegradable					1237:1249	biodegradable	1237:1249	biodegradable	1237:1249	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	8	60	theme	anti-UV	946:952	arg1	investigation					961:973	the actual anti-UV effect investigation	935:973	the actual anti-UV effect investigation	935:973	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	9	61	from	content	1115:1121	arg1	dates					1126:1130	dates	1126:1130	dates	1126:1130	In the meantime, the fall of ascorbic acid content in dates was postponed, and E. coli survivability was increased.					
36991224	7	62	theme	rate	867:870	arg1	measurement					812:822	the measurement	808:822	the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics	808:916	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	8	63	theme	film	1045:1048	arg1	coverage					1050:1057	FOM film coverage	1041:1057	FOM film coverage	1041:1057	Furthermore, in the actual anti-UV effect investigation, the increase of peroxide value and an acid value of grease under FOM film coverage was delayed.					
36991224	10	64	dep	CONCLUSION	1188:1197	arg1	suggest					1211:1217	suggest	1211:1217	suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials	1211:1329	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	10	65	theme	FOM	1223:1225	arg1	film					1227:1230	the FOM film	1219:1230	the FOM film with biodegradable and anti-ultraviolet	1219:1270	CONCLUSION Our results suggest the FOM film with biodegradable and anti-ultraviolet has a high potential for usage in food packaging materials.					
36991224	7	66	theme	water	827:831	arg1	content					833:839	water content	827:839	water content	827:839	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	3	67	theme	Fish	321:324	arg1	FG					334:335	FG	334:335	FG	334:335	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	3	67	theme	Fish	321:324	arg1	gelatin					326:332	Fish gelatin	321:332	Fish gelatin(FG)	321:336	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	2	68	dep	RESULTS	230:236	arg1	obtained					311:318	obtained	311:318	was obtained	307:318	RESULTS In this study, the extraction of MAAs from Dried pyropia haitanensis was obtained.					
36991224	4	69	with	consistent	512:521	arg1	solution					533:540	MAAs solution	528:540	MAAs solution	528:540	The maximum absorption wavelength of the composite film appeared at 334 nm, which was consistent with MAAs solution.					
36991224	6	70	theme	composite	661:669	arg1	film					671:674	The composite film	657:674	The composite film	657:674	The composite film exhibited excellent stability during the 7 days storage period.					
36991224	1	71	theme	mycosporine-like	146:161	arg1	MAAs					140:143	BACKGROUND MAAs	129:143	BACKGROUND MAAs (mycosporine-like amino acids)	129:174	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	71	theme	mycosporine-like	146:161	arg1	acids					169:173	mycosporine-like amino acids	146:173	mycosporine-like amino acids	146:173	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	7	72	theme	vapor	848:852	arg1	rate					867:870	water vapor transmission rate	842:870	water vapor transmission rate	842:870	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36991224	3	73	theme	gelatin	326:332	arg1	films					371:375	Fish gelatin(FG) and oxidized starch(OS)composite films	321:375	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w)	321:407	Fish gelatin(FG) and oxidized starch(OS)composite films embedded with MAAs (0-0.3% w/w) were fabricated.					
36991224	1	74	theme	amino	163:167	arg1	MAAs					140:143	BACKGROUND MAAs	129:143	BACKGROUND MAAs (mycosporine-like amino acids)	129:174	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	1	74	theme	amino	163:167	arg1	acids					169:173	mycosporine-like amino acids	146:173	mycosporine-like amino acids	146:173	BACKGROUND MAAs (mycosporine-like amino acids) are known as the strongest solar guardians in nature.					
36991224	7	75	theme	content	833:839	arg1	measurement					812:822	the measurement	808:822	the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics	808:916	The physicochemical features of composite film were demonstrated by the measurement of water content, water vapor transmission rate, oil transmission, and visual characteristics.					
36943068	9	0	from	%	1407:1407	arg1	days					1414:1417	7 days	1412:1417	7 days	1412:1417	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	2	1	theme	segment-based	294:306	arg1	tPU					336:338	tPU	336:338	tPU	336:338	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	2	1	theme	segment-based	294:306	arg1	polyurethane					322:333	novel ternary soft segment-based biodegradable polyurethane	275:333	novel ternary soft segment-based biodegradable polyurethane (tPU)	275:339	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	4	2	theme	cells	701:705	arg1	vitality					669:676	good vitality	664:676	good vitality (91.3%) of neural stem cells (NSCs) among various tPUs	664:731	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	2	theme	cells	701:705	arg1	%					683:683	91.3%	679:683	91.3%	679:683	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	2	3	theme	ternary	281:287	arg1	tPU					336:338	tPU	336:338	tPU	336:338	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	2	3	theme	ternary	281:287	arg1	polyurethane					322:333	novel ternary soft segment-based biodegradable polyurethane	275:333	novel ternary soft segment-based biodegradable polyurethane (tPU)	275:339	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	6	4	theme	high-resolution	1003:1017	arg1	bioprinting					1035:1045	high-resolution (∼80 μm nozzle) bioprinting	1003:1045	high-resolution (∼80 μm nozzle) bioprinting	1003:1045	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	6	5	dep	high-resolution	1003:1017	arg1	nozzle					1027:1032	nozzle	1027:1032	nozzle	1027:1032	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	1	6	theme	Three-dimensional	106:122	arg1	technology					170:179	an emerging manufacturing technology	144:179	an emerging manufacturing technology to print materials with cells for tissue engineering applications	144:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	1	6	theme	Three-dimensional	106:122	arg1	bioprinting					129:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	1	7	theme	tissue	215:220	arg1	applications					234:245	tissue engineering applications	215:245	tissue engineering applications	215:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	9	8	theme	PUC	1351:1353	arg1	hydrogel					1365:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	8	9	theme	post-crosslinking	1309:1325	arg1	process					1327:1333	a post-crosslinking process	1307:1333	a post-crosslinking process	1307:1333	The PUC hydrogel demonstrated self-healing properties and bioprintability without the need for a post-crosslinking process.					
36943068	7	10	theme	chitosan	1193:1200	arg1	hydrogel					1202:1209	a self-healing chitosan hydrogel	1178:1209	a self-healing chitosan hydrogel	1178:1209	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	9	11	theme	cell	1383:1386	arg1	proliferation					1388:1400	cell proliferation	1383:1400	cell proliferation (∼300% in 7 days)	1383:1418	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	7	12	theme	new	1063:1065	arg1	series					1067:1072	a new series	1061:1072	a new series of double network polyurethane-chitosan composite (PUC) hydrogels	1061:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	13	from	poly	512:515	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	1	14	theme	manufacturing	156:168	arg1	technology					170:179	an emerging manufacturing technology	144:179	an emerging manufacturing technology to print materials with cells for tissue engineering applications	144:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	1	14	theme	manufacturing	156:168	arg1	bioprinting					129:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	0	15	theme	tissue	86:91	arg1	engineering					93:103	soft neural tissue engineering	74:103	soft neural tissue engineering	74:103	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	5	16	theme	tPU2	749:752	arg1	constructs					754:763	The bioprinted tPU2 constructs	734:763	The bioprinted tPU2 constructs	734:763	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	3	17	theme	soft	381:384	arg1	segment					386:392	The ternary soft segment	369:392	The ternary soft segment	369:392	The ternary soft segment included poly(ε-caprolactone) (PCL), polylactide, and poly(3-hydroxybutyrate) (PHB).					
36943068	10	18	dep	bioprinting	1594:1604	arg1	applications					1629:1640	applications	1629:1640	applications	1629:1640	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	4	19	theme	tan δ	629:633	arg1	value					635:639	a greater tan δ value	619:639	a greater tan δ value (∼0.64)	619:647	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	19	theme	tan δ	629:633	arg1	∼0.64					642:646	∼0.64	642:646	∼0.64	642:646	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	9	20	theme	neural	1424:1429	arg1	differentiation					1431:1445	neural differentiation	1424:1445	neural differentiation of NSCs	1424:1453	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	4	21	theme	poly	512:515	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	9	22	dep	proliferation	1388:1400	arg1	%					1407:1407	∼300%	1403:1407	∼300%	1403:1407	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	10	23	theme	bioink	1535:1540	arg1	formulae					1508:1515	new formulae	1504:1515	new formulae of a polyurethane bioink	1504:1540	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	10	23	theme	bioink	1535:1540	arg1	bioink					1580:1585	a polyurethane-chitosan composite bioink	1546:1585	a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications	1546:1640	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	0	24	theme	double	15:20	arg1	composite					52:60	double network polyurethane-chitosan composite	15:60	double network polyurethane-chitosan composite	15:60	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	10	25	theme	tissue	1610:1615	arg1	engineering					1617:1627	tissue engineering	1610:1627	tissue engineering	1610:1627	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	6	26	theme	network	880:886	arg1	hydrogels					898:906	double network composite hydrogels	873:906	double network composite hydrogels	873:906	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	8	27	theme	self-healing	1242:1253	arg1	properties					1255:1264	self-healing properties	1242:1264	self-healing properties	1242:1264	The PUC hydrogel demonstrated self-healing properties and bioprintability without the need for a post-crosslinking process.					
36943068	0	28	theme	polyurethane-chitosan	30:50	arg1	composite					52:60	double network polyurethane-chitosan composite	15:60	double network polyurethane-chitosan composite	15:60	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	4	29	from	PCL	507:509	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	7	30	theme	hydrogels	1130:1138	arg1	series					1067:1072	a new series	1061:1072	a new series of double network polyurethane-chitosan composite (PUC) hydrogels	1061:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	0	31	theme	soft	74:77	arg1	engineering					93:103	soft neural tissue engineering	74:103	soft neural tissue engineering	74:103	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	4	32	theme	neural	689:694	arg1	NSCs					708:711	NSCs	708:711	NSCs	708:711	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	32	theme	neural	689:694	arg1	cells					701:705	neural stem cells	689:705	neural stem cells (NSCs)	689:712	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	10	33	theme	composite	1570:1578	arg1	bioink					1580:1585	a polyurethane-chitosan composite bioink	1546:1585	a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications	1546:1640	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	4	34	from	segment	496:502	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	35	dep	ratio	550:554	arg1	 0.1					570:573	 0.1	570:573	 0.1	570:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	35	dep	ratio	550:554	arg1	 0.2 					564:568	 0.2 	564:568	 0.2 	564:568	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	7	36	theme	PUC	1125:1127	arg1	hydrogels					1130:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	37	theme	PCL	507:509	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	2	38	theme	waterborne	347:356	arg1	processes					358:366	waterborne processes	347:366	waterborne processes	347:366	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	1	39	with	materials	190:198	arg1	cells					205:209	cells	205:209	cells for tissue engineering applications	205:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	7	40	theme	composite	1114:1122	arg1	hydrogels					1130:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	41	theme	PHB	535:537	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	5	42	theme	NSCs	844:847	arg1	differentiation					825:839	neural differentiation	818:839	neural differentiation of NSCs	818:847	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	5	42	theme	NSCs	844:847	arg1	proliferation					782:794	cell proliferation	777:794	cell proliferation (∼200% in 7 days)	777:812	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	7	43	theme	network	1084:1090	arg1	hydrogels					1130:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	2	44	theme	biodegradable	308:320	arg1	tPU					336:338	tPU	336:338	tPU	336:338	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	2	44	theme	biodegradable	308:320	arg1	polyurethane					322:333	novel ternary soft segment-based biodegradable polyurethane	275:333	novel ternary soft segment-based biodegradable polyurethane (tPU)	275:339	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	4	45	theme	various	720:726	arg1	tPUs					728:731	various tPUs	720:731	various tPUs	720:731	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	2	46	theme	soft	289:292	arg1	tPU					336:338	tPU	336:338	tPU	336:338	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	2	46	theme	soft	289:292	arg1	polyurethane					322:333	novel ternary soft segment-based biodegradable polyurethane	275:333	novel ternary soft segment-based biodegradable polyurethane (tPU)	275:339	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	1	47	theme	print	184:188	arg1	materials					190:198	print materials	184:198	print materials with cells for tissue engineering applications	184:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	4	48	theme	stem	696:699	arg1	NSCs					708:711	NSCs	708:711	NSCs	708:711	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	48	theme	stem	696:699	arg1	cells					701:705	neural stem cells	689:705	neural stem cells (NSCs)	689:712	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	49	from	PHB	535:537	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	50	from	ratio	550:554	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	9	51	theme	bioprinted	1340:1349	arg1	hydrogel					1365:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	4	52	theme	0.7 	559:562	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	9	53	theme	composite	1355:1363	arg1	hydrogel					1365:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel	1336:1372	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	9	54	theme	tPU2	1471:1474	arg1	bioink					1476:1481	the tPU2 bioink	1467:1481	the tPU2 bioink	1467:1481	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	2	55	theme	novel	275:279	arg1	tPU					336:338	tPU	336:338	tPU	336:338	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	2	55	theme	novel	275:279	arg1	polyurethane					322:333	novel ternary soft segment-based biodegradable polyurethane	275:333	novel ternary soft segment-based biodegradable polyurethane (tPU)	275:339	In this study, we prepared novel ternary soft segment-based biodegradable polyurethane (tPU) using waterborne processes.					
36943068	5	56	theme	cell	777:780	arg1	proliferation					782:794	cell proliferation	777:794	cell proliferation (∼200% in 7 days)	777:812	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	0	57	theme	neural	79:84	arg1	engineering					93:103	soft neural tissue engineering	74:103	soft neural tissue engineering	74:103	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	1	58	theme	emerging	147:154	arg1	technology					170:179	an emerging manufacturing technology	144:179	an emerging manufacturing technology to print materials with cells for tissue engineering applications	144:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	1	58	theme	emerging	147:154	arg1	bioprinting					129:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting	106:139	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	7	59	theme	self-healing	1180:1191	arg1	hydrogel					1202:1209	a self-healing chitosan hydrogel	1178:1209	a self-healing chitosan hydrogel	1178:1209	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	60	theme	lower	588:592	arg1	stiffness					594:602	lower stiffness	588:602	lower stiffness (∼2.3 kPa)	588:613	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	60	theme	lower	588:592	arg1	kPa					610:612	∼2.3 kPa	605:612	∼2.3 kPa	605:612	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	5	61	theme	bioprinted	738:747	arg1	constructs					754:763	The bioprinted tPU2 constructs	734:763	The bioprinted tPU2 constructs	734:763	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	4	62	theme	soft	491:494	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	1	63	dep	Three-dimensional	106:122	arg1	3D					125:126	3D	125:126	3D	125:126	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	5	64	dep	proliferation	782:794	arg1	%					801:801	∼200%	797:801	∼200% in 7 days	797:811	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	6	65	theme	composite	941:949	arg1	hydrogels					951:959	the composite hydrogels	937:959	the composite hydrogels	937:959	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	4	66	dep	D	517:517	arg1	L-lactide					519:527	L-lactide	519:527	L-lactide	519:527	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	3	67	theme	ternary	373:379	arg1	segment					386:392	The ternary soft segment	369:392	The ternary soft segment	369:392	The ternary soft segment included poly(ε-caprolactone) (PCL), polylactide, and poly(3-hydroxybutyrate) (PHB).					
36943068	10	68	theme	new	1504:1506	arg1	formulae					1508:1515	new formulae	1504:1515	new formulae of a polyurethane bioink	1504:1540	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	4	69	theme	greater	621:627	arg1	value					635:639	a greater tan δ value	619:639	a greater tan δ value (∼0.64)	619:647	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	69	theme	greater	621:627	arg1	∼0.64					642:646	∼0.64	642:646	∼0.64	642:646	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	0	70	theme	network	22:28	arg1	composite					52:60	double network polyurethane-chitosan composite	15:60	double network polyurethane-chitosan composite	15:60	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	6	71	theme	composite	888:896	arg1	hydrogels					898:906	double network composite hydrogels	873:906	double network composite hydrogels	873:906	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	8	72	theme	PUC	1216:1218	arg1	hydrogel					1220:1227	The PUC hydrogel	1212:1227	The PUC hydrogel	1212:1227	The PUC hydrogel demonstrated self-healing properties and bioprintability without the need for a post-crosslinking process.					
36943068	10	73	theme	polyurethane	1522:1533	arg1	bioink					1535:1540	a polyurethane bioink	1520:1540	a polyurethane bioink	1520:1540	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	0	74	theme	composite	52:60	arg1	Development					0:10	Development	0:10	Development of double network polyurethane-chitosan composite	0:60	Development of double network polyurethane-chitosan composite bioinks for soft neural tissue engineering.					
36943068	1	75	theme	engineering	222:232	arg1	applications					234:245	tissue engineering applications	215:245	tissue engineering applications	215:245	Three-dimensional (3D) bioprinting is an emerging manufacturing technology to print materials with cells for tissue engineering applications.					
36943068	9	76	theme	NSCs	1450:1453	arg1	differentiation					1431:1445	neural differentiation	1424:1445	neural differentiation of NSCs	1424:1453	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	9	76	theme	NSCs	1450:1453	arg1	proliferation					1388:1400	cell proliferation	1383:1400	cell proliferation (∼300% in 7 days)	1383:1418	The bioprinted PUC composite hydrogel promoted cell proliferation (∼300% in 7 days) and neural differentiation of NSCs better than the tPU2 bioink.					
36943068	6	77	theme	double	873:878	arg1	hydrogels					898:906	double network composite hydrogels	873:906	double network composite hydrogels	873:906	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	6	78	theme	good	968:971	arg1	biocompatibility					973:988	good biocompatibility	968:988	good biocompatibility	968:988	Meanwhile, tPU2 formed double network composite hydrogels with gelatin or agarose, and the composite hydrogels showed good biocompatibility and achieved high-resolution (∼80 μm nozzle) bioprinting.					
36943068	10	79	theme	polyurethane-chitosan	1548:1568	arg1	bioink					1580:1585	a polyurethane-chitosan composite bioink	1546:1585	a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications	1546:1640	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
36943068	5	80	from	%	801:801	arg1	days					808:811	7 days	806:811	7 days	806:811	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	5	81	theme	neural	818:823	arg1	differentiation					825:839	neural differentiation	818:839	neural differentiation of NSCs	818:847	The bioprinted tPU2 constructs facilitated cell proliferation (∼200% in 7 days) and neural differentiation of NSCs.					
36943068	7	82	theme	polyurethane-chitosan	1092:1112	arg1	hydrogels					1130:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	83	theme	good	664:667	arg1	vitality					669:676	good vitality	664:676	good vitality (91.3%) of neural stem cells (NSCs) among various tPUs	664:731	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	83	theme	good	664:667	arg1	%					683:683	91.3%	679:683	91.3%	679:683	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	4	84	with	tPU2	479:482	arg1	segment					496:502	a soft segment	489:502	a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1	489:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	7	85	theme	double	1077:1082	arg1	hydrogels					1130:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	double network polyurethane-chitosan composite (PUC) hydrogels	1077:1138	In addition, a new series of double network polyurethane-chitosan composite (PUC) hydrogels were developed by combining tPU2 with a self-healing chitosan hydrogel.					
36943068	4	86	theme	molar	544:548	arg1	ratio					550:554	a molar ratio	542:554	a molar ratio of 0.7 : 0.2 : 0.1	542:573	tPU2 with a soft segment of PCL, poly(D,L-lactide), and PHB in a molar ratio of 0.7 : 0.2 : 0.1 demonstrated lower stiffness (∼2.3 kPa) and a greater tan δ value (∼0.64) and maintained good vitality (91.3%) of neural stem cells (NSCs) among various tPUs.					
36943068	10	87	theme	3D	1591:1592	arg1	bioprinting					1594:1604	3D bioprinting	1591:1604	3D bioprinting	1591:1604	This study revealed new formulae of a polyurethane bioink and a polyurethane-chitosan composite bioink for 3D bioprinting and tissue engineering applications.					
35390253	0	0	theme	Two-Phase	76:84	arg1	Systems					86:92	Aqueous Two-Phase Systems	68:92	Aqueous Two-Phase Systems	68:92	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	6	1	theme	Fourier-transform	1071:1087	arg1	spectroscopy					1098:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	3	2	theme	surface	529:535	arg1	spinning					537:544	free surface spinning	524:544	free surface spinning into dry fibers	524:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	0	3	theme	Aqueous	68:74	arg1	Systems					86:92	Aqueous Two-Phase Systems	68:92	Aqueous Two-Phase Systems	68:92	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	2	4	theme	dextran	365:371	arg1	solutions					352:360	immiscible solutions	341:360	immiscible solutions of dextran and polyethylene oxide	341:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	1	5	contain	have	114:117	arg2	applications					128:139	numerous applications	119:139	numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine	119:256	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	1	5	contain	have	114:117	arg1	fibers					107:112	Core-sheath fibers	95:112	Core-sheath fibers	95:112	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	7	6	theme	core	1150:1153	arg1	diameter					1155:1162	the core diameter	1146:1162	the core diameter	1146:1162	Tuning of the core diameter is also demonstrated by varying the weight percentage of dextran added to the reservoir from which the fibers are formed.					
35390253	4	7	theme	core-sheath	782:792	arg1	flow					794:797	a liquid-liquid core-sheath flow	766:797	a liquid-liquid core-sheath flow that is drawn into a liquid bridge	766:832	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	0	8	theme	Systems	86:92	arg1	Spinning					56:63	Free Surface Spinning	43:63	Free Surface Spinning of Aqueous Two-Phase Systems	43:92	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	7	9	theme	diameter	1155:1162	arg1	Tuning					1136:1141	Tuning	1136:1141	Tuning of the core diameter	1136:1162	Tuning of the core diameter is also demonstrated by varying the weight percentage of dextran added to the reservoir from which the fibers are formed.					
35390253	4	10	theme	liquid-liquid	768:780	arg1	flow					794:797	a liquid-liquid core-sheath flow	766:797	a liquid-liquid core-sheath flow that is drawn into a liquid bridge	766:832	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	4	11	theme	solutions	740:748	arg1	flows					702:706	complex flows	694:706	complex flows of the phase-separating polymer solutions	694:748	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	4	12	theme	polymer	732:738	arg1	solutions					740:748	the phase-separating polymer solutions	711:748	the phase-separating polymer solutions	711:748	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	2	13	from	solutions	352:360	arg1	generation					303:312	the generation	299:312	the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide	299:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	6	14	theme	attenuated	1043:1052	arg1	spectroscopy					1098:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	1	15	theme	advanced	178:185	arg1	manufacturing					187:199	advanced manufacturing	178:199	advanced manufacturing to materials for drug delivery and regenerative medicine	178:256	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	2	16	theme	tunable	278:284	arg1	approach					286:293	a simple and tunable approach	265:293	a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide	265:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	6	17	theme	confocal	1115:1122	arg1	microscopy					1124:1133	confocal microscopy	1115:1133	confocal microscopy	1115:1133	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	3	18	theme	dry	551:553	arg1	fibers					555:560	dry fibers	551:560	dry fibers	551:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	2	19	theme	fibers	329:334	arg1	generation					303:312	the generation	299:312	the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide	299:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	5	20	theme	core-sheath	876:886	arg1	fiber					888:892	a core-sheath fiber	874:892	a core-sheath fiber through extensional flow	874:917	This liquid bridge then elongates into a core-sheath fiber through extensional flow as the contacting substrate is withdrawn.					
35390253	7	21	theme	dextran	1221:1227	arg1	percentage					1207:1216	the weight percentage	1196:1216	the weight percentage of dextran added to the reservoir from which the fibers are formed	1196:1283	Tuning of the core diameter is also demonstrated by varying the weight percentage of dextran added to the reservoir from which the fibers are formed.					
35390253	6	22	theme	fibers	994:999	arg1	structure					977:985	The core-sheath structure	961:985	The core-sheath structure of the fibers produced by this approach	961:1025	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	2	23	theme	core-sheath	317:327	arg1	fibers					329:334	core-sheath fibers	317:334	core-sheath fibers	317:334	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	3	24	theme	polymer	453:459	arg1	molecules					461:469	polymer molecules	453:469	polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers	453:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	0	25	theme	Polymer	25:31	arg1	Fibers					33:38	Core-Sheath Polymer Fibers	13:38	Core-Sheath Polymer Fibers	13:38	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	4	26	dep	substrate	651:659	arg1	such					662:665	such	662:665	such	662:665	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	1	27	theme	Core-sheath	95:105	arg1	fibers					107:112	Core-sheath fibers	95:112	Core-sheath fibers	95:112	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	5	28	theme	liquid	840:845	arg1	bridge					847:852	This liquid bridge	835:852	This liquid bridge	835:852	This liquid bridge then elongates into a core-sheath fiber through extensional flow as the contacting substrate is withdrawn.					
35390253	0	29	theme	Core-Sheath	13:23	arg1	Fibers					33:38	Core-Sheath Polymer Fibers	13:38	Core-Sheath Polymer Fibers	13:38	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	4	30	theme	core-sheath	592:602	arg1	fibers					604:609	these core-sheath fibers	586:609	these core-sheath fibers	586:609	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	1	31	theme	drug	218:221	arg1	delivery					223:230	drug delivery	218:230	drug delivery	218:230	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	3	32	theme	free	524:527	arg1	spinning					537:544	free surface spinning	524:544	free surface spinning into dry fibers	524:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	6	33	theme	reflection	1060:1069	arg1	spectroscopy					1098:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	0	34	theme	Fibers	33:38	arg1	Formation					0:8	Formation	0:8	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.	0:93	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	6	35	theme	core-sheath	965:975	arg1	structure					977:985	The core-sheath structure	961:985	The core-sheath structure of the fibers produced by this approach	961:1025	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	4	36	theme	liquid	820:825	arg1	bridge					827:832	a liquid bridge	818:832	a liquid bridge	818:832	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	3	37	theme	dextran	482:488	arg1	phases					513:518	the dextran and polyethylene oxide phases	478:518	the dextran and polyethylene oxide phases for free surface spinning into dry fibers	478:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	0	38	theme	Surface	48:54	arg1	Spinning					56:63	Free Surface Spinning	43:63	Free Surface Spinning of Aqueous Two-Phase Systems	43:92	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	6	39	theme	total	1054:1058	arg1	spectroscopy					1098:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	3	40	theme	molecules	461:469	arg1	entanglement					437:448	entanglement	437:448	entanglement	437:448	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	3	41	theme	polyethylene	494:505	arg1	oxide					507:511	polyethylene oxide	494:511	polyethylene oxide	494:511	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	0	42	theme	Free	43:46	arg1	Spinning					56:63	Free Surface Spinning	43:63	Free Surface Spinning of Aqueous Two-Phase Systems	43:92	Formation of Core-Sheath Polymer Fibers by Free Surface Spinning of Aqueous Two-Phase Systems.					
35390253	4	43	with	contact	630:636	arg1	substrate					651:659	a solid substrate	643:659	a solid substrate (such as a microneedle)	643:683	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	1	44	theme	numerous	119:126	arg1	applications					128:139	numerous applications	119:139	numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine	119:256	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	7	45	theme	weight	1200:1205	arg1	percentage					1207:1216	the weight percentage	1196:1216	the weight percentage of dextran added to the reservoir from which the fibers are formed	1196:1283	Tuning of the core diameter is also demonstrated by varying the weight percentage of dextran added to the reservoir from which the fibers are formed.					
35390253	5	46	theme	contacting	926:935	arg1	substrate					937:945	the contacting substrate	922:945	the contacting substrate	922:945	This liquid bridge then elongates into a core-sheath fiber through extensional flow as the contacting substrate is withdrawn.					
35390253	4	47	theme	complex	694:700	arg1	flows					702:706	complex flows	694:706	complex flows of the phase-separating polymer solutions	694:748	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	2	48	theme	immiscible	341:350	arg1	solutions					352:360	immiscible solutions	341:360	immiscible solutions of dextran and polyethylene oxide	341:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	1	49	theme	regenerative	236:247	arg1	medicine					249:256	regenerative medicine	236:256	regenerative medicine	236:256	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	2	50	theme	simple	267:272	arg1	approach					286:293	a simple and tunable approach	265:293	a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide	265:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	1	51	theme	composite	154:162	arg1	materials					164:172	composite materials	154:172	composite materials	154:172	Core-sheath fibers have numerous applications ranging from composite materials for advanced manufacturing to materials for drug delivery and regenerative medicine.					
35390253	3	52	theme	oxide	507:511	arg1	phases					513:518	the dextran and polyethylene oxide phases	478:518	the dextran and polyethylene oxide phases for free surface spinning into dry fibers	478:560	This approach exploits the entanglement of polymer molecules within the dextran and polyethylene oxide phases for free surface spinning into dry fibers.					
35390253	5	53	theme	extensional	902:912	arg1	flow					914:917	extensional flow	902:917	extensional flow	902:917	This liquid bridge then elongates into a core-sheath fiber through extensional flow as the contacting substrate is withdrawn.					
35390253	6	54	theme	infrared	1089:1096	arg1	spectroscopy					1098:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	attenuated total reflection Fourier-transform infrared spectroscopy	1043:1109	The core-sheath structure of the fibers produced by this approach is confirmed by attenuated total reflection Fourier-transform infrared spectroscopy and confocal microscopy.					
35390253	2	55	theme	oxide	390:394	arg1	solutions					352:360	immiscible solutions	341:360	immiscible solutions of dextran and polyethylene oxide	341:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	4	56	theme	solid	645:649	arg1	substrate					651:659	a solid substrate	643:659	a solid substrate (such as a microneedle)	643:683	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35390253	2	57	theme	polyethylene	377:388	arg1	oxide					390:394	polyethylene oxide	377:394	polyethylene oxide	377:394	Here, a simple and tunable approach for the generation of core-sheath fibers from immiscible solutions of dextran and polyethylene oxide is described.					
35390253	4	58	theme	phase-separating	715:730	arg1	solutions					740:748	the phase-separating polymer solutions	711:748	the phase-separating polymer solutions	711:748	The mechanism by which these core-sheath fibers are produced after contact with a solid substrate (such as a microneedle) involves complex flows of the phase-separating polymer solutions, giving rise to a liquid-liquid core-sheath flow that is drawn into a liquid bridge.					
35950076	6	0	theme	mice	946:949	arg1	edema					955:959	mice paw edema	946:959	mice paw edema of 86% and 75%	946:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	7	1	theme	anti-inflammatory	1107:1123	arg1	effect					1125:1130	the highest anti-inflammatory effect	1095:1130	the highest anti-inflammatory effect	1095:1130	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	2	2	theme	Graells	374:380	arg1	Methods					327:333	Methods The powdered leaves	327:353	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv	327:408	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	8	3	dep	the	1204:1206	arg1	leaves					1208:1213	leaves	1208:1213	leaves extracts of B. coriacea and U. leptocladon	1208:1256	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	1	4	theme	extracts	262:269	arg1	activities					207:216	the anti-inflammatory activities	185:216	the anti-inflammatory activities	185:216	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	1	4	theme	extracts	262:269	arg1	composition					236:246	phytochemical composition	222:246	phytochemical composition	222:246	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	8	5	theme	cardiac	1303:1309	arg1	glycoside					1311:1319	cardiac glycoside	1303:1319	cardiac glycoside	1303:1319	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	9	6	contain	contain	1451:1457	arg2	phytochemicals					1459:1472	phytochemicals	1459:1472	phytochemicals with anti-inflammatory activities	1459:1506	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	9	6	contain	contain	1451:1457	arg1	extracts					1395:1402	The crude leaves extracts	1378:1402	The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv	1378:1449	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	1	7	theme	study	163:167	arg1	objective					145:153	The objective	141:153	The objective of this study	141:167	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	9	8	theme	anti-inflammatory	1479:1495	arg1	activities					1497:1506	anti-inflammatory activities	1479:1506	anti-inflammatory activities	1479:1506	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	9	9	dep	crude	1382:1386	arg1	leaves					1388:1393	leaves	1388:1393	leaves	1388:1393	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	1	10	dep	Background	130:139	arg1	was					169:171	was	169:171	was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	169:324	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	8	11	theme	saponins	1357:1364	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	0	12	theme	Graells	93:99	arg1	Extracts					65:72	Extracts	65:72	Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv	65:127	Anti-Inflammatory and Phytochemical Analysis of the Crude Leaves Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv.					
35950076	6	13	theme	percent	924:930	arg1	inhibition					932:941	percent inhibition	924:941	percent inhibition on mice paw edema of 86% and 75%	924:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	7	14	theme	highest	1099:1105	arg1	effect					1125:1130	the highest anti-inflammatory effect	1095:1130	the highest anti-inflammatory effect	1095:1130	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	3	15	theme	Graells	540:546	arg1	extracts					512:519	extracts	512:519	extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	512:574	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	9	16	theme	Oliv	1446:1449	arg1	extracts					1395:1402	The crude leaves extracts	1378:1402	The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv	1378:1449	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	8	17	theme	alkaloids	1292:1300	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	9	18	theme	crude	1382:1386	arg1	extracts					1395:1402	The crude leaves extracts	1378:1402	The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv	1378:1449	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	7	19	theme	Oliv	1083:1086	arg1	fraction					1044:1051	The ethanol fraction	1032:1051	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv	1032:1086	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	7	19	theme	Oliv	1083:1086	arg1	mg/kg					1058:1062	100 mg/kg	1054:1062	100 mg/kg	1054:1062	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	6	20	theme	leptocladon	852:862	arg1	Results					841:847	Results	841:847	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg)	841:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	20	theme	leptocladon	852:862	arg1	Oliv					864:867	U. leptocladon Oliv	849:867	U. leptocladon Oliv (200 mg/kg)	849:879	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	20	theme	leptocladon	852:862	arg1	mg/kg					874:878	200 mg/kg	870:878	200 mg/kg	870:878	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	3	21	theme	Oliv	571:574	arg1	extracts					512:519	extracts	512:519	extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	512:574	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	8	22	theme	leptocladon	1246:1256	arg1	extracts					1215:1222	extracts	1215:1222	extracts of B. coriacea and U. leptocladon	1215:1256	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	4	23	theme	extracts	717:724	arg1	composition					691:701	phytochemical composition	677:701	phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	677:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	3	24	theme	the	501:503	arg1	activity					489:496	Anti-inflammatory activity	471:496	Anti-inflammatory activity of the	471:503	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	4	25	theme	Standard	634:641	arg1	methods					643:649	Standard methods	634:649	Standard methods	634:649	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	4	26	theme	composition	691:701	arg1	analysis					665:672	analysis	665:672	analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	665:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	8	27	theme	phytochemical	1178:1190	arg1	analysis					1192:1199	The phytochemical analysis	1174:1199	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon	1174:1256	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	3	28	theme	Anti-inflammatory	471:487	arg1	activity					489:496	Anti-inflammatory activity	471:496	Anti-inflammatory activity of the	471:503	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	7	29	theme	U.	1068:1069	arg1	Oliv					1083:1086	U. leptocladon Oliv	1068:1086	U. leptocladon Oliv	1068:1086	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	3	30	theme	edema	621:625	arg1	model					627:631	carrageenan-induced paw edema model	597:631	carrageenan-induced paw edema model	597:631	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	6	31	dep	Results	841:847	arg1	Results					841:847	Results	841:847	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg)	841:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	31	dep	Results	841:847	arg1	Oliv					864:867	U. leptocladon Oliv	849:867	U. leptocladon Oliv (200 mg/kg)	849:879	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	31	dep	Results	841:847	arg1	mg/kg					874:878	200 mg/kg	870:878	200 mg/kg	870:878	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	31	dep	Results	841:847	arg1	mg/kg					910:914	200 mg/kg	906:914	200 mg/kg	906:914	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	31	dep	Results	841:847	arg1	Graells					897:903	B. coriacea Graells	885:903	B. coriacea Graells (200 mg/kg)	885:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	2	32	theme	Oliv	405:408	arg1	Methods					327:333	Methods The powdered leaves	327:353	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv	327:408	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	0	33	theme	Anti-Inflammatory	0:16	arg1	Analysis					36:43	Anti-Inflammatory and Phytochemical Analysis	0:43	Anti-Inflammatory and Phytochemical Analysis of the Crude	0:56	Anti-Inflammatory and Phytochemical Analysis of the Crude Leaves Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv.					
35950076	1	34	theme	Graells	290:296	arg1	extracts					262:269	the leaves extracts	251:269	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	251:324	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	7	35	theme	leptocladon	1071:1081	arg1	Oliv					1083:1086	U. leptocladon Oliv	1068:1086	U. leptocladon Oliv	1068:1086	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	2	36	dep	powdered	339:346	arg1	leaves					348:353	leaves	348:353	leaves	348:353	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	6	37	theme	carrageenan	995:1005	arg1	injection					1007:1015	carrageenan injection	995:1015	carrageenan injection	995:1015	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	7	38	theme	carrageenan	1151:1161	arg1	injection					1163:1171	carrageenan injection	1151:1171	carrageenan injection	1151:1171	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	6	39	theme	%	974:974	arg1	edema					955:959	mice paw edema	946:959	mice paw edema of 86% and 75%	946:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	9	40	with	phytochemicals	1459:1472	arg1	activities					1497:1506	anti-inflammatory activities	1479:1506	anti-inflammatory activities	1479:1506	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	3	41	theme	carrageenan-induced	597:615	arg1	edema					621:625	carrageenan-induced paw edema	597:625	carrageenan-induced paw edema model	597:631	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	2	42	theme	soxhlet	443:449	arg1	methods					462:468	soxhlet extraction methods	443:468	soxhlet extraction methods	443:468	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	2	43	theme	extraction	451:460	arg1	methods					462:468	soxhlet extraction methods	443:468	soxhlet extraction methods	443:468	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	6	44	dep	B.	885:886	arg1	coriacea					888:895	coriacea	888:895	coriacea	888:895	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	0	45	theme	Oliv	124:127	arg1	Extracts					65:72	Extracts	65:72	Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv	65:127	Anti-Inflammatory and Phytochemical Analysis of the Crude Leaves Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv.					
35950076	1	46	dep	the	251:253	arg1	leaves					255:260	leaves	255:260	leaves	255:260	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	3	47	theme	paw	617:619	arg1	edema					621:625	carrageenan-induced paw edema	597:625	carrageenan-induced paw edema model	597:631	Anti-inflammatory activity of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv were evaluated using carrageenan-induced paw edema model.					
35950076	4	48	theme	phytochemical	677:689	arg1	composition					691:701	phytochemical composition	677:701	phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	677:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	5	49	theme	variance	831:838	arg1	analysis					819:826	one way analysis	811:826	one way analysis of variance	811:838	Data analysis was done using one way analysis of variance.					
35950076	4	50	used	used	656:659	arg2	methods					643:649	Standard methods	634:649	Standard methods	634:649	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	4	51	dep	the	706:708	arg1	leaves					710:715	leaves	710:715	leaves	710:715	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	4	52	theme	the	706:708	arg1	extracts					717:724	the leaves extracts	706:724	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	706:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	9	53	theme	Graells	1419:1425	arg1	extracts					1395:1402	The crude leaves extracts	1378:1402	The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv	1378:1449	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	1	54	theme	Oliv	321:324	arg1	extracts					262:269	the leaves extracts	251:269	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	251:324	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	5	55	theme	Data	782:785	arg1	analysis					787:794	Data analysis	782:794	Data analysis	782:794	Data analysis was done using one way analysis of variance.					
35950076	9	56	dep	Conclusion	1367:1376	arg1	contain					1451:1457	contain	1451:1457	contain phytochemicals with anti-inflammatory activities	1451:1506	Conclusion The crude leaves extracts of B. coriacea Graells and U. leptocladon Oliv contain phytochemicals with anti-inflammatory activities.					
35950076	8	57	theme	the	1204:1206	arg1	analysis					1192:1199	The phytochemical analysis	1174:1199	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon	1174:1256	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	1	58	theme	phytochemical	222:234	arg1	composition					236:246	phytochemical composition	222:246	phytochemical composition	222:246	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	6	59	theme	%	966:966	arg1	edema					955:959	mice paw edema	946:959	mice paw edema of 86% and 75%	946:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	8	60	theme	phenols	1334:1340	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	6	61	from	inhibition	932:941	arg1	edema					955:959	mice paw edema	946:959	mice paw edema of 86% and 75%	946:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	4	62	theme	Oliv	776:779	arg1	extracts					717:724	the leaves extracts	706:724	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	706:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	0	63	theme	Crude	52:56	arg1	Analysis					36:43	Anti-Inflammatory and Phytochemical Analysis	0:43	Anti-Inflammatory and Phytochemical Analysis of the Crude	0:56	Anti-Inflammatory and Phytochemical Analysis of the Crude Leaves Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv.					
35950076	6	64	theme	B.	885:886	arg1	Results					841:847	Results	841:847	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg)	841:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	64	theme	B.	885:886	arg1	Graells					897:903	B. coriacea Graells	885:903	B. coriacea Graells (200 mg/kg)	885:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	64	theme	B.	885:886	arg1	mg/kg					910:914	200 mg/kg	906:914	200 mg/kg	906:914	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	8	65	theme	tannins	1283:1289	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	6	66	theme	U.	849:850	arg1	Results					841:847	Results	841:847	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg)	841:915	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	66	theme	U.	849:850	arg1	Oliv					864:867	U. leptocladon Oliv	849:867	U. leptocladon Oliv (200 mg/kg)	849:879	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	6	66	theme	U.	849:850	arg1	mg/kg					874:878	200 mg/kg	870:878	200 mg/kg	870:878	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	8	67	theme	quinones	1343:1350	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	7	68	theme	ethanol	1036:1042	arg1	fraction					1044:1051	The ethanol fraction	1032:1051	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv	1032:1086	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	7	68	theme	ethanol	1036:1042	arg1	mg/kg					1058:1062	100 mg/kg	1054:1062	100 mg/kg	1054:1062	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	8	69	theme	glycoside	1311:1319	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	2	70	dep	Methods	327:333	arg1	powdered					339:346	powdered	339:346	powdered	339:346	Methods The powdered leaves of Boscia coriacea Graells and Uvaria leptocladon Oliv were extracted by maceration and soxhlet extraction methods.					
35950076	8	71	theme	flavonoids	1322:1331	arg1	presence					1271:1278	the presence	1267:1278	the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins	1267:1364	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	1	72	theme	anti-inflammatory	189:205	arg1	activities					207:216	the anti-inflammatory activities	185:216	the anti-inflammatory activities	185:216	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	4	73	theme	Graells	745:751	arg1	extracts					717:724	the leaves extracts	706:724	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	706:779	Standard methods were used for analysis of phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	8	74	theme	coriacea	1230:1237	arg1	extracts					1215:1222	extracts	1215:1222	extracts of B. coriacea and U. leptocladon	1215:1256	The phytochemical analysis of the leaves extracts of B. coriacea and U. leptocladon revealed the presence of tannins, alkaloids, cardiac glycoside, flavonoids, phenols, quinones, and saponins.					
35950076	1	75	theme	the	251:253	arg1	extracts					262:269	the leaves extracts	251:269	the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv	251:324	Background The objective of this study was to evaluate the anti-inflammatory activities and phytochemical composition of the leaves extracts of Boscia coriacea Graells and Uvaria leptocladon Oliv.					
35950076	5	76	theme	way	815:817	arg1	analysis					819:826	one way analysis	811:826	one way analysis of variance	811:838	Data analysis was done using one way analysis of variance.					
35950076	6	77	theme	paw	951:953	arg1	edema					955:959	mice paw edema	946:959	mice paw edema of 86% and 75%	946:974	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35950076	0	78	theme	Phytochemical	22:34	arg1	Analysis					36:43	Anti-Inflammatory and Phytochemical Analysis	0:43	Anti-Inflammatory and Phytochemical Analysis of the Crude	0:56	Anti-Inflammatory and Phytochemical Analysis of the Crude Leaves Extracts of Boscia Coriacea Graells and Uvaria Leptocladon Oliv.					
35950076	7	79	theme	injection	1163:1171	arg1	hours					1142:1146	six hours	1138:1146	six hours of carrageenan injection	1138:1171	The ethanol fraction (100 mg/kg) of U. leptocladon Oliv showed the highest anti-inflammatory effect after six hours of carrageenan injection.					
35950076	6	80	theme	injection	1007:1015	arg1	hours					986:990	six hours	982:990	six hours of carrageenan injection	982:1015	Results U. leptocladon Oliv (200 mg/kg) and B. coriacea Graells (200 mg/kg) showed percent inhibition on mice paw edema of 86% and 75% after six hours of carrageenan injection, respectively.					
35026219	2	0	from	propionate	438:447	arg1	solvents					504:511	organic solvents	496:511	organic solvents	496:511	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	1	1	theme	biobased	168:175	arg1	products					177:184	fully biobased products	162:184	fully biobased products with functionality	162:203	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	1	2	theme	increasing	256:265	arg1	demand					267:272	the increasing demand	252:272	the increasing demand for environmental sustainability	252:305	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	4	3	theme	visible	876:882	arg1	transmittance					890:902	71% visible light transmittance	872:902	71% visible light transmittance	872:902	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	1	4	with	products	177:184	arg1	functionality					191:203	functionality	191:203	functionality	191:203	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	5	5	theme	UV	968:969	arg1	light					971:975	Nearly 100% UV light	956:975	Nearly 100% UV light	956:975	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	1	6	theme	petroleum-based	341:355	arg1	counterparts					357:368	petroleum-based counterparts	341:368	petroleum-based counterparts	341:368	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	3	7	theme	green	728:732	arg1	solvent					745:751	a green processing solvent	726:751	a green processing solvent	726:751	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	3	7	theme	green	728:732	arg1	ethanol/water					709:721	acidic ethanol/water	702:721	acidic ethanol/water	702:721	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	1	8	theme	environmental	278:290	arg1	sustainability					292:305	environmental sustainability	278:305	environmental sustainability	278:305	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	3	9	theme	processing	734:743	arg1	solvent					745:751	a green processing solvent	726:751	a green processing solvent	726:751	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	3	9	theme	processing	734:743	arg1	ethanol/water					709:721	acidic ethanol/water	702:721	acidic ethanol/water	702:721	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	4	10	theme	5	785:785	arg1	%					786:786	%	786:786	%	786:786	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	4	11	dep	%	846:846	arg1	98					844:845	98	844:845	98	844:845	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	2	12	with	propionate	438:447	arg1	solubility					482:491	significantly improved solubility	459:491	significantly improved solubility	459:491	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	6	13	theme	novel	1126:1130	arg1	films					1147:1151	novel fully biobased films	1126:1151	novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications	1126:1239	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	6	14	theme	packaging	1218:1226	arg1	applications					1228:1239	potential packaging applications	1208:1239	potential packaging applications	1208:1239	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	4	15	theme	UV	848:849	arg1	light					851:855	approximately 98% UV light	830:855	approximately 98% UV light	830:855	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	2	16	theme	forest	561:566	arg1	residuals					576:584	the forest harvest residuals	557:584	the forest harvest residuals	557:584	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	5	17	theme	%	996:996	arg1	addition					1002:1009	20% OSL addition	994:1009	20% OSL addition	994:1009	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	6	18	theme	potential	1208:1216	arg1	applications					1228:1239	potential packaging applications	1208:1239	potential packaging applications	1208:1239	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	1	19	theme	green	210:214	arg1	fashion					216:222	a green fashion	208:222	a green fashion	208:222	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	6	20	theme	biobased	1138:1145	arg1	films					1147:1151	novel fully biobased films	1126:1151	novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications	1126:1239	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	5	21	theme	visible	1016:1022	arg1	transmittance					1030:1042	visible light transmittance	1016:1042	visible light transmittance	1016:1042	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	2	22	theme	organic	496:502	arg1	solvents					504:511	organic solvents	496:511	organic solvents	496:511	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	6	23	with	films	1147:1151	arg1	protection					1193:1202	excellent UV protection	1180:1202	excellent UV protection	1180:1202	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	6	23	with	films	1147:1151	arg1	transparency					1163:1174	high transparency	1158:1174	high transparency	1158:1174	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	5	24	theme	light	1024:1028	arg1	transmittance					1030:1042	visible light transmittance	1016:1042	visible light transmittance	1016:1042	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	4	25	theme	CP	813:814	arg1	film					816:819	the CP film	809:819	the CP film	809:819	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	2	26	theme	chitin	431:436	arg1	CP					450:451	CP	450:451	CP	450:451	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	2	26	theme	chitin	431:436	arg1	propionate					438:447	chitin propionate	431:447	chitin propionate (CP) with significantly improved solubility in organic solvents	431:511	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	1	27	theme	white	321:325	arg1	"					336:336	"white pollution"	320:336	"white pollution" by petroleum-based counterparts	320:368	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	4	28	theme	tensile	905:911	arg1	properties					925:934	tensile and thermal properties	905:934	tensile and thermal properties	905:934	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	5	29	dep	%	966:966	arg1	100					963:965	100	963:965	100	963:965	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	0	30	theme	biocomposite	61:72	arg1	films					74:78	fully biocomposite films	55:78	fully biocomposite films based on chitin and lignin using ethanol/water as processing solvents	55:148	Developing highly transparent yet ultraviolet blocking fully biocomposite films based on chitin and lignin using ethanol/water as processing solvents.					
35026219	1	31	theme	pollution	327:335	arg1	"					336:336	"white pollution"	320:336	"white pollution" by petroleum-based counterparts	320:368	Developing fully biobased products with functionality in a green fashion is highly desirable to meet the increasing demand for environmental sustainability and mitigate "white pollution" by petroleum-based counterparts.					
35026219	5	32	theme	20	994:995	arg1	%					996:996	%	996:996	%	996:996	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	2	33	from	shells	396:401	arg1	chitin					377:382	chitin	377:382	chitin from shrimp shells	377:401	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	6	34	theme	alternative	1094:1104	arg1	solution					1106:1113	an alternative solution	1091:1113	an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications	1091:1239	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	2	35	theme	improved	473:480	arg1	solubility					482:491	significantly improved solubility	459:491	significantly improved solubility	459:491	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	0	36	theme	processing	130:139	arg1	solvents					141:148	processing solvents	130:148	processing solvents	130:148	Developing highly transparent yet ultraviolet blocking fully biocomposite films based on chitin and lignin using ethanol/water as processing solvents.					
35026219	0	36	theme	processing	130:139	arg1	ethanol/water					113:125	ethanol/water	113:125	ethanol/water	113:125	Developing highly transparent yet ultraviolet blocking fully biocomposite films based on chitin and lignin using ethanol/water as processing solvents.					
35026219	5	37	theme	OSL	998:1000	arg1	addition					1002:1009	20% OSL addition	994:1009	20% OSL addition	994:1009	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	3	38	theme	biobased	597:604	arg1	composite					606:614	The fully biobased composite	587:614	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker	587:667	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	6	39	theme	UV	1190:1191	arg1	protection					1193:1202	excellent UV protection	1180:1202	excellent UV protection	1180:1202	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	4	40	theme	light	884:888	arg1	transmittance					890:902	71% visible light transmittance	872:902	71% visible light transmittance	872:902	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	6	41	theme	excellent	1180:1188	arg1	protection					1193:1202	excellent UV protection	1180:1202	excellent UV protection	1180:1202	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	4	42	theme	OSL	788:790	arg1	addition					792:799	the 5% OSL addition	781:799	the 5% OSL addition	781:799	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	2	43	theme	harvest	568:574	arg1	residuals					576:584	the forest harvest residuals	557:584	the forest harvest residuals	557:584	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	4	44	theme	%	786:786	arg1	addition					792:799	the 5% OSL addition	781:799	the 5% OSL addition	781:799	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	5	45	dep	light	971:975	arg1	%					966:966	%	966:966	%	966:966	Nearly 100% UV light was blocked with 20% OSL addition, but visible light transmittance was moderately sacrificed.					
35026219	2	46	theme	shrimp	389:394	arg1	shells					396:401	shrimp shells	389:401	shrimp shells	389:401	Here, chitin from shrimp shells was propionylated to obtain chitin propionate (CP) with significantly improved solubility in organic solvents, organosolv lignin (OSL) was extracted from the forest harvest residuals.					
35026219	4	47	dep	light	851:855	arg1	%					846:846	%	846:846	%	846:846	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
35026219	3	48	theme	acidic	702:707	arg1	solvent					745:751	a green processing solvent	726:751	a green processing solvent	726:751	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	3	48	theme	acidic	702:707	arg1	ethanol/water					709:721	acidic ethanol/water	702:721	acidic ethanol/water	702:721	The fully biobased composite consisting of CP as a matrix and OSL as a UV-blocker were successfully prepared using acidic ethanol/water as a green processing solvent.					
35026219	6	49	theme	high	1158:1161	arg1	transparency					1163:1174	high transparency	1158:1174	high transparency	1158:1174	This study provides an alternative solution to produce novel fully biobased films with high transparency yet excellent UV protection for potential packaging applications.					
35026219	4	50	theme	thermal	917:923	arg1	properties					925:934	tensile and thermal properties	905:934	tensile and thermal properties	905:934	The results indicated that the 5% OSL addition enabled the CP film to block approximately 98% UV light while allowing 71% visible light transmittance; tensile and thermal properties were also retained.					
36274222	9	0	theme	corn	1595:1598	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	0	theme	corn	1595:1598	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	6	1	theme	1	1088:1088	arg1	response					1076:1083	the fluoro-switching response	1055:1083	the fluoro-switching response	1055:1083	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	11	2	dep	antibiotics	2016:2026	arg1	the					2012:2014	the	2012:2014	the	2012:2014	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	3	3	theme	toxic	641:645	arg1	oxo-anions					647:656	toxic oxo-anions	641:656	toxic oxo-anions	641:656	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	11	4	theme	appropriate	2057:2067	arg1	antibiotics					2016:2026	antibiotics	2016:2026	antibiotics	2016:2026	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	7	5	theme	HOMO-LUMO	1218:1226	arg1	levels					1235:1240	the HOMO-LUMO energy levels	1214:1240	the HOMO-LUMO energy levels of fluorophore and analytes	1214:1268	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	1	6	theme	natural	258:264	arg1	resources					266:274	several natural resources	250:274	several natural resources which is one of the major consequences for fatality to human health	250:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	11	7	theme	carcinogenic	2100:2111	arg1	"					2137:2137	carcinogenic drug molecule "roxarsone"	2100:2137	carcinogenic drug molecule "roxarsone" in food specimens	2100:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	3	8	theme	ppb	665:667	arg1	level					669:673	the ppb level	661:673	the ppb level	661:673	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	4	9	theme	turn-off	812:819	arg1	"					820:820	"turn-off"	811:820	"turn-off"	811:820	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	3	10	from	level	669:673	arg1	detection					612:620	the selective detection	598:620	the selective detection of antibiotics and toxic oxo-anions at the ppb level	598:673	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	11	11	from	analysis	2088:2095	arg1	specimens					2147:2155	food specimens	2142:2155	food specimens	2142:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	1	12	theme	antibiotics	186:196	arg1	growth					206:211	the growth	202:211	the growth of industry	202:223	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	1	12	theme	antibiotics	186:196	arg1	use					179:181	Frequent use	170:181	Frequent use of antibiotics	170:196	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	10	13	theme	"	1920:1920	arg1	response					1922:1929	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1847:1929	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	0	14	theme	Reversible	111:120	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	14	theme	Reversible	111:120	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	3	15	theme	-based	544:549	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	15	theme	-based	544:549	arg1	MOF					576:578	MOF	576:578	MOF	576:578	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	15	theme	-based	544:549	arg1	1					582:582	1	582:582	1	582:582	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	15	theme	-based	544:549	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	8	16	theme	nitro-group-containing	1434:1455	arg1	"					1472:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	11	17	theme	molecule	2118:2125	arg1	"					2137:2137	carcinogenic drug molecule "roxarsone"	2100:2137	carcinogenic drug molecule "roxarsone" in food specimens	2100:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	9	18	theme	useful	1646:1651	arg1	features					1663:1670	its useful potential features	1642:1670	its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price	1642:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	18	theme	useful	1646:1651	arg1	biocompatibility					1680:1695	biocompatibility	1680:1695	biocompatibility	1680:1695	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	18	theme	useful	1646:1651	arg1	price					1762:1766	low commercial price	1747:1766	low commercial price	1747:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	18	theme	useful	1646:1651	arg1	flexibility					1730:1740	good flexibility	1725:1740	good flexibility	1725:1740	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	3	19	used	used	589:592	arg2	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	19	used	used	589:592	arg2	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	10	20	theme	visual	1797:1802	arg1	detection					1804:1812	visual detection	1797:1812	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	8	21	theme	"	1472:1472	arg1	detection					1406:1414	the detection	1402:1414	the detection of a carcinogenic nitro-group-containing drug "roxarsone"	1402:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	11	22	theme	@	1944:1944	arg1	CS					1945:1946	1@CS	1943:1946	1@CS	1943:1946	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	9	23	theme	environment	1502:1512	arg1	view					1478:1481	view	1478:1481	view of the sustainable environment along with quick-responsive merit of 1	1478:1551	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	6	24	theme	extensive	992:1000	arg1	investigation					1014:1026	An extensive theoretical investigation	989:1026	An extensive theoretical investigation	989:1026	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	0	25	theme	Sustainable	50:60	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	25	theme	Sustainable	50:60	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	9	26	dep	in	1557:1558	arg1	situ					1560:1563	situ	1560:1563	situ	1560:1563	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	0	27	theme	Starch	67:72	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	27	theme	Starch	67:72	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	5	28	theme	reversible	872:881	arg1	"					934:934	fluorescence "on-off-on"	911:934	fluorescence "on-off-on"	911:934	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	5	28	theme	reversible	872:881	arg1	phenomena					900:908	The antibiotic-triggered reversible fluoro-switching phenomena	847:908	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on")	847:935	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	9	29	theme	innocuous	1714:1722	arg1	biocompatibility					1680:1695	biocompatibility	1680:1695	biocompatibility	1680:1695	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	11	30	theme	promising	1961:1969	arg1	material					1985:1992	a promising smart sensing material	1959:1992	a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	1959:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	9	31	theme	1	1551:1551	arg1	merit					1542:1546	quick-responsive merit	1525:1546	quick-responsive merit of 1	1525:1551	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	5	32	theme	fluorescence	911:922	arg1	"					934:934	fluorescence "on-off-on"	911:934	fluorescence "on-off-on"	911:934	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	5	32	theme	fluorescence	911:922	arg1	phenomena					900:908	The antibiotic-triggered reversible fluoro-switching phenomena	847:908	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on")	847:935	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	9	33	theme	good	1725:1728	arg1	flexibility					1730:1740	good flexibility	1725:1740	good flexibility	1725:1740	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	4	34	theme	dissimilar	727:736	arg1	sulfadiazine					749:760	the electronically dissimilar antibiotic sulfadiazine	708:760	the electronically dissimilar antibiotic sulfadiazine	708:760	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	6	35	theme	fluoro-switching	1059:1074	arg1	response					1076:1083	the fluoro-switching response	1055:1083	the fluoro-switching response	1055:1083	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	2	36	theme	hazardous	444:452	arg1	organics					454:461	those hazardous organics	438:461	those hazardous organics	438:461	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	8	37	theme	detection	1362:1370	arg1	ability					1372:1378	the versatile detection ability	1348:1378	the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone"	1348:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	2	38	theme	sensing	366:372	arg1	materials					374:382	smart sensing materials	360:382	smart sensing materials	360:382	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	1	39	theme	resources	266:274	arg1	pollution					237:245	the pollution	233:245	the pollution of several natural resources which is one of the major consequences for fatality to human health	233:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	5	40	theme	on-off-on	925:933	arg1	"					934:934	fluorescence "on-off-on"	911:934	fluorescence "on-off-on"	911:934	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	5	40	theme	on-off-on	925:933	arg1	phenomena					900:908	The antibiotic-triggered reversible fluoro-switching phenomena	847:908	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on")	847:935	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	7	41	theme	sensing	1314:1320	arg1	activity					1322:1329	such a fluoro-switchable sensing activity	1289:1329	such a fluoro-switchable sensing activity	1289:1329	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	9	42	theme	low	1747:1749	arg1	price					1762:1766	low commercial price	1747:1766	low commercial price	1747:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	1	43	dep	human	331:335	arg1	to					328:329	to	328:329	to	328:329	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	2	44	theme	ultrasensitive	410:423	arg1	detection					425:433	ultrasensitive detection	410:433	ultrasensitive detection of those hazardous organics	410:461	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	4	45	dep	"	805:805	arg1	processes					822:830	processes	822:830	processes	822:830	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	9	46	theme	gel	1569:1571	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	46	theme	gel	1569:1571	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	3	47	theme	selective	602:610	arg1	detection					612:620	the selective detection	598:620	the selective detection of antibiotics and toxic oxo-anions at the ppb level	598:673	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	4	48	theme	fluorescence	784:795	arg1	"					805:805	fluorescence "turn-on"	784:805	fluorescence "turn-on"	784:805	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	4	49	theme	turn-on	798:804	arg1	"					805:805	fluorescence "turn-on"	784:805	fluorescence "turn-on"	784:805	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	10	50	theme	fluoro-switchable	1879:1895	arg1	"					1920:1920	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on"	1847:1920	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	3	51	theme	bonded	491:496	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	51	theme	bonded	491:496	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	1	52	theme	major	296:300	arg1	consequences					302:313	the major consequences	292:313	the major consequences for fatality to human health	292:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	9	53	theme	@	1585:1585	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	53	theme	@	1585:1585	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	10	54	theme	above	1821:1825	arg1	analytes					1827:1834	the above analytes	1817:1834	the above analytes	1817:1834	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	3	55	theme	porous	475:480	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	55	theme	porous	475:480	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	1	56	theme	industry	216:223	arg1	growth					206:211	the growth	202:211	the growth of industry	202:223	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	1	56	theme	industry	216:223	arg1	use					179:181	Frequent use	170:181	Frequent use of antibiotics	170:196	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	8	57	theme	carcinogenic	1421:1432	arg1	"					1472:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	3	58	theme	free-NH2	521:528	arg1	moiety					530:535	a free-NH2 moiety	519:535	a free-NH2 moiety	519:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	9	59	theme	=	1593:1593	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	59	theme	=	1593:1593	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	11	60	from	specimens	2147:2155	arg1	analysis					2088:2095	the real-field analysis	2073:2095	the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	2073:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	11	61	from	"	2137:2137	arg1	specimens					2147:2155	food specimens	2142:2155	food specimens	2142:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	11	62	theme	real-field	2077:2086	arg1	analysis					2088:2095	the real-field analysis	2073:2095	the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	2073:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	7	63	theme	energy	1228:1233	arg1	levels					1235:1240	the HOMO-LUMO energy levels	1214:1240	the HOMO-LUMO energy levels of fluorophore and analytes	1214:1268	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	3	64	theme	oxo-anions	647:656	arg1	detection					612:620	the selective detection	598:620	the selective detection of antibiotics and toxic oxo-anions at the ppb level	598:673	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	1	65	theme	several	250:256	arg1	resources					266:274	several natural resources	250:274	several natural resources which is one of the major consequences for fatality to human health	250:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	6	66	theme	oxo-anions	1151:1160	arg1	sensing					1140:1146	the sensing	1136:1146	the sensing of oxo-anions	1136:1160	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	10	67	theme	colorimetric	1897:1908	arg1	"					1920:1920	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on"	1847:1920	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	1	68	theme	Frequent	170:177	arg1	use					179:181	Frequent use	170:181	Frequent use of antibiotics	170:196	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	11	69	theme	food	2142:2145	arg1	specimens					2147:2155	food specimens	2142:2155	food specimens	2142:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	11	70	theme	drug	2113:2116	arg1	"					2137:2137	carcinogenic drug molecule "roxarsone"	2100:2137	carcinogenic drug molecule "roxarsone" in food specimens	2100:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	10	71	theme	reversible	1868:1877	arg1	"					1920:1920	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on"	1847:1920	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	3	72	theme	metal-organic	551:563	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	72	theme	metal-organic	551:563	arg1	MOF					576:578	MOF	576:578	MOF	576:578	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	72	theme	metal-organic	551:563	arg1	1					582:582	1	582:582	1	582:582	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	72	theme	metal-organic	551:563	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	10	73	theme	analytes	1827:1834	arg1	response					1922:1929	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1847:1929	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	10	73	theme	analytes	1827:1834	arg1	detection					1804:1812	visual detection	1797:1812	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	11	74	theme	smart	1971:1975	arg1	material					1985:1992	a promising smart sensing material	1959:1992	a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	1959:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	11	75	theme	antibiotics	2016:2026	arg1	monitoring					1998:2007	monitoring	1998:2007	monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	1998:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	8	76	theme	drug	1457:1460	arg1	"					1472:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	6	77	theme	antibiotics	1115:1125	arg1	class					1106:1110	a class	1104:1110	a class of antibiotics	1104:1125	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	10	78	theme	on-off-on	1911:1919	arg1	"					1920:1920	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on"	1847:1920	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	9	79	theme	quick-responsive	1525:1540	arg1	merit					1542:1546	quick-responsive merit	1525:1546	quick-responsive merit of 1	1525:1551	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	8	80	theme	roxarsone	1463:1471	arg1	"					1472:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	a carcinogenic nitro-group-containing drug "roxarsone"	1419:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	11	81	theme	1	1943:1943	arg1	@					1944:1944	@	1944:1944	@	1944:1944	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	5	82	theme	fluoro-switching	883:898	arg1	"					934:934	fluorescence "on-off-on"	911:934	fluorescence "on-off-on"	911:934	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	5	82	theme	fluoro-switching	883:898	arg1	phenomena					900:908	The antibiotic-triggered reversible fluoro-switching phenomena	847:908	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on")	847:935	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	9	83	theme	potential	1653:1661	arg1	features					1663:1670	its useful potential features	1642:1670	its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price	1642:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	83	theme	potential	1653:1661	arg1	biocompatibility					1680:1695	biocompatibility	1680:1695	biocompatibility	1680:1695	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	83	theme	potential	1653:1661	arg1	price					1762:1766	low commercial price	1747:1766	low commercial price	1747:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	83	theme	potential	1653:1661	arg1	flexibility					1730:1740	good flexibility	1725:1740	good flexibility	1725:1740	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	10	84	theme	MOF	1773:1775	arg1	composite					1777:1785	The MOF composite	1769:1785	The MOF composite	1769:1785	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	9	85	theme	sustainable	1490:1500	arg1	environment					1502:1512	the sustainable environment	1486:1512	the sustainable environment	1486:1512	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	6	86	theme	theoretical	1002:1012	arg1	investigation					1014:1026	An extensive theoretical investigation	989:1026	An extensive theoretical investigation	989:1026	An extensive theoretical investigation was performed to establish the fluoro-switching response of 1, triggered by a class of antibiotics and also the sensing of oxo-anions.					
36274222	11	87	theme	oxo-anions	2032:2041	arg1	monitoring					1998:2007	monitoring	1998:2007	monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	1998:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	0	88	theme	Corn	62:65	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	88	theme	Corn	62:65	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	89	theme	Gel	74:76	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	89	theme	Gel	74:76	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	5	90	theme	antibiotic-triggered	851:870	arg1	"					934:934	fluorescence "on-off-on"	911:934	fluorescence "on-off-on"	911:934	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	5	90	theme	antibiotic-triggered	851:870	arg1	phenomena					900:908	The antibiotic-triggered reversible fluoro-switching phenomena	847:908	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on")	847:935	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	1	91	theme	human	331:335	arg1	health					337:342	fatality to human health	319:342	fatality to human health	319:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	11	92	theme	sensing	1977:1983	arg1	material					1985:1992	a promising smart sensing material	1959:1992	a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	1959:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	0	93	theme	Fluoro-Switchable	93:109	arg1	Sensor					122:127	a Fluoro-Switchable Reversible Sensor	91:127	a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions	91:167	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	0	93	theme	Fluoro-Switchable	93:109	arg1	Composite					78:86	Sustainable Corn Starch Gel Composite	50:86	Sustainable Corn Starch Gel Composite	50:86	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	2	94	theme	materials	374:382	arg1	Exploration					345:355	Exploration	345:355	Exploration of smart sensing materials	345:382	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	0	95	theme	Luminescent	7:17	arg1	MOF					19:21	Highly Luminescent MOF	0:21	Highly Luminescent MOF	0:21	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	9	96	theme	in	1557:1558	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	96	theme	in	1557:1558	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	7	97	theme	fluoro-switchable	1296:1312	arg1	activity					1322:1329	such a fluoro-switchable sensing activity	1289:1329	such a fluoro-switchable sensing activity	1289:1329	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	11	98	theme	"	2137:2137	arg1	analysis					2088:2095	the real-field analysis	2073:2095	the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens	2073:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
36274222	8	99	theme	versatile	1352:1360	arg1	ability					1372:1378	the versatile detection ability	1348:1378	the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone"	1348:1472	Sensor 1 showed the versatile detection ability which is reflected by the detection of a carcinogenic nitro-group-containing drug "roxarsone".					
36274222	2	100	theme	smart	360:364	arg1	materials					374:382	smart sensing materials	360:382	smart sensing materials	360:382	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	9	101	theme	CS	1590:1591	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	101	theme	CS	1590:1591	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	102	theme	MOF	1565:1567	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	102	theme	MOF	1565:1567	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	103	theme	commercial	1751:1760	arg1	price					1762:1766	low commercial price	1747:1766	low commercial price	1747:1766	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	3	104	theme	robust	468:473	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	104	theme	robust	468:473	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	0	105	dep	In	31:32	arg1	Situ					34:37	Situ	34:37	Situ	34:37	Highly Luminescent MOF and Its In Situ Fabricated Sustainable Corn Starch Gel Composite as a Fluoro-Switchable Reversible Sensor Triggered by Antibiotics and Oxo-Anions.					
36274222	7	106	theme	analytes	1261:1268	arg1	levels					1235:1240	the HOMO-LUMO energy levels	1214:1240	the HOMO-LUMO energy levels of fluorophore and analytes	1214:1268	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	2	107	theme	organics	454:461	arg1	detection					425:433	ultrasensitive detection	410:433	ultrasensitive detection of those hazardous organics	410:461	Exploration of smart sensing materials is highly anticipated for ultrasensitive detection of those hazardous organics.					
36274222	3	108	theme	antibiotics	625:635	arg1	detection					612:620	the selective detection	598:620	the selective detection of antibiotics and toxic oxo-anions at the ppb level	598:673	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	1	109	theme	consequences	302:313	arg1	one					285:287	one	285:287	one	285:287	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	1	109	theme	consequences	302:313	arg1	consequences					302:313	the major consequences	292:313	the major consequences for fatality to human health	292:342	Frequent use of antibiotics and the growth of industry lead to the pollution of several natural resources which is one of the major consequences for fatality to human health.					
36274222	9	110	theme	CS	1586:1587	arg1	composite					1573:1581	an in situ MOF gel composite	1554:1581	an in situ MOF gel composite (1@CS; CS = corn starch)	1554:1606	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	9	110	theme	CS	1586:1587	arg1	starch					1600:1605	1@CS; CS = corn starch	1584:1605	1@CS; CS = corn starch	1584:1605	In view of the sustainable environment along with quick-responsive merit of 1, an in situ MOF gel composite (1@CS; CS = corn starch) is prepared using 1 and CS due to its useful potential features such as biocompatibility, toxicologically innocuous, good flexibility, and low commercial price.					
36274222	7	111	theme	fluorophore	1245:1255	arg1	levels					1235:1240	the HOMO-LUMO energy levels	1214:1240	the HOMO-LUMO energy levels of fluorophore and analytes	1214:1268	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	4	112	theme	antibiotic	738:747	arg1	sulfadiazine					749:760	the electronically dissimilar antibiotic sulfadiazine	708:760	the electronically dissimilar antibiotic sulfadiazine	708:760	The framework is able to detect the electronically dissimilar antibiotic sulfadiazine and nitrofurazone via fluorescence "turn-on" and "turn-off" processes, respectively.					
36274222	3	113	theme	hydrogen	482:489	arg1	network					498:504	The robust porous hydrogen bonded network	464:504	The robust porous hydrogen bonded network encompassing a free-NH2 moiety	464:535	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	3	113	theme	hydrogen	482:489	arg1	framework					565:573	Zn(II)-based metal-organic framework	538:573	Zn(II)-based metal-organic framework (MOF) (1)	538:583	The robust porous hydrogen bonded network encompassing a free-NH2 moiety, Zn(II)-based metal-organic framework (MOF) (1), is used for the selective detection of antibiotics and toxic oxo-anions at the ppb level.					
36274222	5	114	theme	fluorimetric	968:979	arg1	method					981:986	the fluorimetric method	964:986	the fluorimetric method	964:986	The antibiotic-triggered reversible fluoro-switching phenomena (fluorescence "on-off-on") are also observed by using the fluorimetric method.					
36274222	7	115	theme	levels	1235:1240	arg1	interchange					1199:1209	the interchange	1195:1209	the interchange of the HOMO-LUMO energy levels of fluorophore and analytes	1195:1268	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	7	115	theme	levels	1235:1240	arg1	responsible					1273:1283	responsible	1273:1283	responsible	1273:1283	This investigation reveals that the interchange of the HOMO-LUMO energy levels of fluorophore and analytes is responsible for such a fluoro-switchable sensing activity.					
36274222	10	116	theme	antibiotic-triggered	1847:1866	arg1	"					1920:1920	antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on"	1847:1920	visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response	1797:1929	The MOF composite exhibited visual detection of the above analytes as well as antibiotic-triggered reversible fluoro-switchable colorimetric "on-off-on" response.					
36274222	11	117	theme	roxarsone	2128:2136	arg1	"					2137:2137	carcinogenic drug molecule "roxarsone"	2100:2137	carcinogenic drug molecule "roxarsone" in food specimens	2100:2155	Therefore, 1@CS represents a promising smart sensing material for monitoring of the antibiotics and oxo-anions, particularly appropriate for the real-field analysis of carcinogenic drug molecule "roxarsone" in food specimens.					
35725199	1	0	theme	food	231:234	arg1	industry					236:243	food industry	231:243	food industry	231:243	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	6	1	theme	same	1014:1017	arg1	profile					1037:1043	the same butyrate-dominant profile	1010:1043	the same butyrate-dominant profile with KGM	1010:1052	KOGM, owned the same butyrate-dominant profile with KGM, was utilized fast.					
35725199	8	2	theme	propionate-dominant	1187:1205	arg1	pattern					1207:1213	a propionate-dominant pattern	1185:1213	a propionate-dominant pattern	1185:1213	Severe deacetylation reduced fermentability and led DKGM to a propionate-dominant pattern.					
35725199	6	3	used	utilized	1059:1066	arg2	KOGM					998:1001	KOGM	998:1001	KOGM	998:1001	KOGM, owned the same butyrate-dominant profile with KGM, was utilized fast.					
35725199	4	4	theme	distinct	782:789	arg1	composition					801:811	the distinct microbial composition	778:811	the distinct microbial composition	778:811	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	1	5	from	glucomannan	303:313	arg1	distinct					282:289	distinct	282:289	distinct	282:289	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	0	6	theme	microbiota	105:114	arg1	diversity					76:84	diversity	76:84	diversity	76:84	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	0	6	theme	microbiota	105:114	arg1	outputs					90:96	outputs	90:96	outputs	90:96	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	4	7	theme	binding	691:697	arg1	ability					699:705	water binding ability	685:705	water binding ability	685:705	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	2	8	theme	physicochemical	374:388	arg1	properties					390:399	physicochemical properties	374:399	physicochemical properties	374:399	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	0	9	theme	gut	101:103	arg1	microbiota					105:114	gut microbiota	101:114	gut microbiota	101:114	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	6	10	theme	butyrate-dominant	1019:1035	arg1	profile					1037:1043	the same butyrate-dominant profile	1010:1043	the same butyrate-dominant profile with KGM	1010:1052	KOGM, owned the same butyrate-dominant profile with KGM, was utilized fast.					
35725199	3	11	theme	structural	527:536	arg1	complexity					538:547	structural complexity	527:547	structural complexity of KGM	527:554	This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism.					
35725199	5	12	theme	Catenibacterium	892:906	arg1	abundances					878:887	higher abundances	871:887	higher abundances of Catenibacterium and Megasphaera	871:922	Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM.					
35725199	2	13	theme	following	443:451	arg1	outcomes					453:460	the following outcomes	439:460	the following outcomes	439:460	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	2	14	theme	structures	359:368	arg1	roles					335:339	the roles	331:339	the roles of their distinct structures and physicochemical properties in directing microbiota community	331:433	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	2	14	theme	structures	359:368	arg1	outcomes					453:460	the following outcomes	439:460	the following outcomes	439:460	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	0	15	theme	Structural	0:9	arg1	complexity					11:20	Structural complexity	0:20	Structural complexity of Konjac glucomannan and its derivatives	0:62	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	7	16	theme	highest	1101:1107	arg1	fermentability					1109:1122	the highest fermentability	1097:1122	the highest fermentability	1097:1122	However, KGM possessed the highest fermentability.					
35725199	0	17	dep	diversity	76:84	arg1	the					72:74	the	72:74	the	72:74	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	2	18	theme	distinct	350:357	arg1	structures					359:368	their distinct structures	344:368	their distinct structures	344:368	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	0	19	theme	Konjac	25:30	arg1	glucomannan					32:42	Konjac glucomannan	25:42	Konjac glucomannan	25:42	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	3	20	theme	KGM	552:554	arg1	complexity					538:547	structural complexity	527:547	structural complexity of KGM	527:554	This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism.					
35725199	3	20	theme	KGM	552:554	arg1	metabolism					590:599	microbial metabolism	580:599	microbial metabolism	580:599	This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism.					
35725199	3	20	theme	KGM	552:554	arg1	derivatives					564:574	its derivatives	560:574	its derivatives	560:574	This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism.					
35725199	2	21	theme	microbiota	414:423	arg1	community					425:433	microbiota community	414:433	microbiota community	414:433	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	7	22	contain	possessed	1087:1095	arg1	KGM					1083:1085	KGM	1083:1085	KGM	1083:1085	However, KGM possessed the highest fermentability.					
35725199	7	22	contain	possessed	1087:1095	arg2	fermentability					1109:1122	the highest fermentability	1097:1122	the highest fermentability	1097:1122	However, KGM possessed the highest fermentability.					
35725199	5	23	theme	higher	871:876	arg1	abundances					878:887	higher abundances	871:887	higher abundances of Catenibacterium and Megasphaera	871:922	Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM.					
35725199	4	24	theme	water	685:689	arg1	ability					699:705	water binding ability	685:705	water binding ability	685:705	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	4	25	theme	chain	663:667	arg1	aggregation					669:679	molecular chain aggregation	653:679	molecular chain aggregation	653:679	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	0	26	theme	glucomannan	32:42	arg1	complexity					11:20	Structural complexity	0:20	Structural complexity of Konjac glucomannan and its derivatives	0:62	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	1	27	theme	Konjac	296:301	arg1	glucomannan					303:313	Konjac glucomannan	296:313	Konjac glucomannan (KGM)	296:319	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	1	27	theme	Konjac	296:301	arg1	KGM					316:318	KGM	316:318	KGM	316:318	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	6	28	with	profile	1037:1043	arg1	KGM					1050:1052	KGM	1050:1052	KGM	1050:1052	KOGM, owned the same butyrate-dominant profile with KGM, was utilized fast.					
35725199	2	29	theme	properties	390:399	arg1	roles					335:339	the roles	331:339	the roles of their distinct structures and physicochemical properties in directing microbiota community	331:433	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	2	29	theme	properties	390:399	arg1	outcomes					453:460	the following outcomes	439:460	the following outcomes	439:460	However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood.					
35725199	0	30	theme	derivatives	52:62	arg1	complexity					11:20	Structural complexity	0:20	Structural complexity of Konjac glucomannan and its derivatives	0:62	Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota.					
35725199	1	31	from	derivatives	216:226	arg1	industry					236:243	food industry	231:243	food industry	231:243	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	5	32	from	abundances	878:887	arg1	distinctive					856:866	distinctive	856:866	distinctive	856:866	Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM.					
35725199	8	33	theme	Severe	1125:1130	arg1	deacetylation					1132:1144	Severe deacetylation	1125:1144	Severe deacetylation	1125:1144	Severe deacetylation reduced fermentability and led DKGM to a propionate-dominant pattern.					
35725199	3	34	theme	microbial	580:588	arg1	metabolism					590:599	microbial metabolism	580:599	microbial metabolism	580:599	This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism.					
35725199	5	35	from	distinctive	856:866	arg1	abundances					878:887	higher abundances	871:887	higher abundances of Catenibacterium and Megasphaera	871:922	Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM.					
35725199	4	36	theme	outcomes	817:824	arg1	profile					826:832	outcomes profile	817:832	outcomes profile	817:832	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	4	37	theme	enzymatic	744:752	arg1	degradation					754:764	enzymatic degradation	744:764	enzymatic degradation	744:764	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	5	38	theme	Megasphaera	912:922	arg1	abundances					878:887	higher abundances	871:887	higher abundances of Catenibacterium and Megasphaera	871:922	Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM.					
35725199	4	39	theme	microbial	791:799	arg1	composition					801:811	the distinct microbial composition	778:811	the distinct microbial composition	778:811	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	1	40	theme	used	211:214	arg1	derivatives					216:226	two most widely used derivatives	195:226	two most widely used derivatives in food industry	195:243	Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM).					
35725199	4	41	theme	molecular	653:661	arg1	aggregation					669:679	molecular chain aggregation	653:679	molecular chain aggregation	653:679	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
35725199	4	42	theme	structural	622:631	arg1	alterations					633:643	structural alterations	622:643	structural alterations	622:643	Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile.					
36649873	2	0	theme	food	377:380	arg1	wastes					382:387	food wastes	377:387	food wastes	377:387	BC was cost-effectively produced by utilizing food wastes, and PGPE was ex situ impregnated into its hydrogel.					
36649873	6	1	theme	re-wetting	925:934	arg1	cycles					936:941	three consecutive re-wetting cycles	907:941	three consecutive re-wetting cycles	907:941	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	10	2	theme	50 	1557:1559	arg1	%					1560:1560	%	1560:1560	%	1560:1560	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	9	3	theme	inhibition	1424:1433	arg1	zone					1416:1419	a 17 mm zone	1408:1419	a 17 mm zone of inhibition against S. aureus	1408:1451	The BC-PGPE composite produced a 17 mm zone of inhibition against S. aureus, while no inhibition zone was formed against E. coli.					
36649873	3	4	theme	BC	568:569	arg1	morphology					545:554	a nanofibrous and microporous morphology	515:554	a nanofibrous and microporous morphology of pristine BC	515:569	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	7	5	theme	plate	1117:1121	arg1	count					1123:1127	plate count	1117:1127	plate count	1117:1127	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	3	6	theme	BC-PGPE	604:610	arg1	composite					612:620	BC-PGPE composite	604:620	BC-PGPE composite	604:620	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	9	7	theme	inhibition	1463:1472	arg1	zone					1474:1477	no inhibition zone	1460:1477	no inhibition zone	1460:1477	The BC-PGPE composite produced a 17 mm zone of inhibition against S. aureus, while no inhibition zone was formed against E. coli.					
36649873	3	8	theme	microporous	533:543	arg1	morphology					545:554	a nanofibrous and microporous morphology	515:554	a nanofibrous and microporous morphology of pristine BC	515:569	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	4	9	theme	chemical	684:691	arg1	interaction					693:703	the chemical interaction	680:703	the chemical interaction of PGPE with BC nanofibers	680:730	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	5	10	theme	%	759:759	arg1	water					761:765	97 % water	756:765	97 % water of its dry weight	756:783	BC-PGPE composite held 97 % water of its dry weight and retained it for more than 48 h.					
36649873	7	11	theme	minimum	1055:1061	arg1	MBC					1091:1093	MBC	1091:1093	MBC	1091:1093	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	7	11	theme	minimum	1055:1061	arg1	concentration					1076:1088	minimum bactericidal concentration	1055:1088	minimum bactericidal concentration (MBC)	1055:1094	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	10	12	theme	aureus	1592:1597	arg1	growth					1579:1584	the growth	1575:1584	the growth of S. aureus and E. coli	1575:1609	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	11	13	theme	dressing	1726:1733	arg1	material					1735:1742	a promising antibacterial wound dressing material	1694:1742	a promising antibacterial wound dressing material	1694:1742	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	11	13	theme	dressing	1726:1733	arg1	composite					1675:1683	BC-PGPE composite	1667:1683	BC-PGPE composite	1667:1683	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	5	14	theme	BC-PGPE	733:739	arg1	composite					741:749	BC-PGPE composite	733:749	BC-PGPE composite	733:749	BC-PGPE composite held 97 % water of its dry weight and retained it for more than 48 h.					
36649873	11	15	theme	antibacterial	1706:1718	arg1	material					1735:1742	a promising antibacterial wound dressing material	1694:1742	a promising antibacterial wound dressing material	1694:1742	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	11	15	theme	antibacterial	1706:1718	arg1	composite					1675:1683	BC-PGPE composite	1667:1683	BC-PGPE composite	1667:1683	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	7	16	theme	inhibitory	1023:1032	arg1	MIC					1049:1051	MIC	1049:1051	MIC	1049:1051	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	7	16	theme	inhibitory	1023:1032	arg1	concentration					1034:1046	minimum inhibitory concentration	1015:1046	minimum inhibitory concentration (MIC)	1015:1052	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	1	17	theme	bacterial	179:187	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	0	18	theme	potential	103:111	arg1	applications					124:135	potential biomedical applications	103:135	potential biomedical applications	103:135	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	3	19	theme	scanning	457:464	arg1	observation					496:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	5	20	theme	dry	774:776	arg1	weight					778:783	its dry weight	770:783	its dry weight	770:783	BC-PGPE composite held 97 % water of its dry weight and retained it for more than 48 h.					
36649873	7	21	theme	BC-PGPE	978:984	arg1	composite					986:994	the BC-PGPE composite	974:994	the BC-PGPE composite	974:994	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	7	22	dep	concentration	1034:1046	arg1	methods					1129:1135	methods	1129:1135	methods	1129:1135	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	3	23	theme	FE-SEM	488:493	arg1	observation					496:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	0	24	theme	low-cost	15:22	arg1	cellulose-pomegranate					34:54	low-cost bacterial cellulose-pomegranate	15:54	low-cost bacterial cellulose-pomegranate	15:54	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	1	25	theme	potential	296:304	arg1	applications					317:328	potential biomedical applications	296:328	potential biomedical applications	296:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	3	26	theme	microscopic	475:485	arg1	observation					496:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	0	27	theme	cellulose-pomegranate	34:54	arg1	Development					0:10	Development	0:10	Development of low-cost bacterial cellulose-pomegranate	0:54	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	6	28	theme	pristine	889:896	arg1	BC					898:899	pristine BC	889:899	pristine BC	889:899	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	8	29	with	composite	1306:1314	arg1	BC					1321:1322	BC	1321:1322	BC	1321:1322	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	0	30	theme	extract-based	61:73	arg1	composite					89:97	extract-based antibacterial composite	61:97	extract-based antibacterial composite for potential biomedical applications	61:135	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	10	31	theme	BC-PGPE	1520:1526	arg1	composite					1528:1536	BC-PGPE composite	1520:1536	BC-PGPE composite	1520:1536	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	11	32	theme	promising	1696:1704	arg1	material					1735:1742	a promising antibacterial wound dressing material	1694:1742	a promising antibacterial wound dressing material	1694:1742	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	11	32	theme	promising	1696:1704	arg1	composite					1675:1683	BC-PGPE composite	1667:1683	BC-PGPE composite	1667:1683	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	8	33	theme	PGPE	1142:1145	arg1	extract					1147:1153	The PGPE extract	1138:1153	The PGPE extract	1138:1153	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	6	34	theme	better	853:858	arg1	capabilities					871:882	better reswelling capabilities	853:882	better reswelling capabilities	853:882	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	4	35	theme	infrared	641:648	arg1	spectroscopy					657:668	infrared (FTIR) spectroscopy	641:668	infrared (FTIR) spectroscopy	641:668	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	10	36	theme	100 	1547:1550	arg1	%					1551:1551	%	1551:1551	%	1551:1551	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	1	37	theme	peel	272:275	arg1	extract					277:283	pomegranate (Punica granatum L.) peel extract	239:283	pomegranate (Punica granatum L.) peel extract (PGPE)	239:290	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	37	theme	peel	272:275	arg1	Punica					252:257	Punica	252:257	Punica	252:257	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	37	theme	peel	272:275	arg1	PGPE					286:289	PGPE	286:289	PGPE	286:289	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	8	38	theme	antimicrobial	1167:1179	arg1	activity					1181:1188	good antimicrobial activity	1162:1188	good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC	1162:1322	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	4	39	with	interaction	693:703	arg1	nanofibers					721:730	BC nanofibers	718:730	BC nanofibers	718:730	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	6	40	theme	BC-PGPE	825:831	arg1	composite					833:841	The BC-PGPE composite	821:841	The BC-PGPE composite	821:841	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	10	41	theme	%	1560:1560	arg1	reduction					1562:1570	a 100 % and 50 % reduction	1545:1570	a 100 % and 50 % reduction in the growth of S. aureus and E. coli	1545:1609	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	11	42	theme	study	1647:1651	arg1	findings					1630:1637	The findings	1626:1637	The findings of this study	1626:1651	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	3	43	theme	pristine	559:566	arg1	BC					568:569	pristine BC	559:569	pristine BC	559:569	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	1	44	theme	BC	200:201	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	6	45	theme	consecutive	913:923	arg1	cycles					936:941	three consecutive re-wetting cycles	907:941	three consecutive re-wetting cycles	907:941	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	1	46	theme	-based	203:208	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	4	47	theme	PGPE	708:711	arg1	interaction					693:703	the chemical interaction	680:703	the chemical interaction of PGPE with BC nanofibers	680:730	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	10	48	theme	coli	1606:1609	arg1	growth					1579:1584	the growth	1575:1584	the growth of S. aureus and E. coli	1575:1609	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	5	49	theme	97 	756:758	arg1	%					759:759	%	759:759	%	759:759	BC-PGPE composite held 97 % water of its dry weight and retained it for more than 48 h.					
36649873	4	50	dep	Fourier	623:629	arg1	transform					631:639	transform	631:639	transform infrared (FTIR) spectroscopy	631:668	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	1	51	theme	antibacterial	210:222	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	52	theme	pomegranate	239:249	arg1	extract					277:283	pomegranate (Punica granatum L.) peel extract	239:283	pomegranate (Punica granatum L.) peel extract (PGPE)	239:290	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	52	theme	pomegranate	239:249	arg1	Punica					252:257	Punica	252:257	Punica	252:257	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	52	theme	pomegranate	239:249	arg1	PGPE					286:289	PGPE	286:289	PGPE	286:289	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	53	dep	Punica	252:257	arg1	L.					268:269	Punica granatum L.	252:269	Punica granatum L.	252:269	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	8	54	theme	extract	1294:1300	arg1	form					1286:1289	the form	1282:1289	the form of extract	1282:1300	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	3	55	theme	composite	612:620	arg1	development					589:599	the development	585:599	the development of BC-PGPE composite	585:620	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	7	56	theme	bactericidal	1063:1074	arg1	MBC					1091:1093	MBC	1091:1093	MBC	1091:1093	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	7	56	theme	bactericidal	1063:1074	arg1	concentration					1076:1088	minimum bactericidal concentration	1055:1088	minimum bactericidal concentration (MBC)	1055:1094	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	5	57	theme	weight	778:783	arg1	water					761:765	97 % water	756:765	97 % water of its dry weight	756:783	BC-PGPE composite held 97 % water of its dry weight and retained it for more than 48 h.					
36649873	4	58	dep	infrared	641:648	arg1	FTIR					651:654	FTIR	651:654	FTIR	651:654	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	1	59	theme	low-cost	170:177	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	4	60	theme	BC	718:719	arg1	nanofibers					721:730	BC nanofibers	718:730	BC nanofibers	718:730	Fourier transform infrared (FTIR) spectroscopy indicated the chemical interaction of PGPE with BC nanofibers.					
36649873	11	61	theme	wound	1720:1724	arg1	material					1735:1742	a promising antibacterial wound dressing material	1694:1742	a promising antibacterial wound dressing material	1694:1742	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	11	61	theme	wound	1720:1724	arg1	composite					1675:1683	BC-PGPE composite	1667:1683	BC-PGPE composite	1667:1683	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	0	62	theme	biomedical	113:122	arg1	applications					124:135	potential biomedical applications	103:135	potential biomedical applications	103:135	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	1	63	theme	cellulose	189:197	arg1	composite					224:232	low-cost bacterial cellulose (BC)-based antibacterial composite	170:232	low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications	170:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	8	64	dep	aureus	1213:1218	arg1	composite					1306:1314	composite	1306:1314	composite	1306:1314	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	8	64	dep	aureus	1213:1218	arg1	both					1274:1277	both	1274:1277	both	1274:1277	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	8	65	theme	better	1341:1346	arg1	activity					1348:1355	relatively better activity	1330:1355	relatively better activity against the former	1330:1374	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	7	66	theme	minimum	1015:1021	arg1	MIC					1049:1051	MIC	1049:1051	MIC	1049:1051	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	7	66	theme	minimum	1015:1021	arg1	concentration					1034:1046	minimum inhibitory concentration	1015:1046	minimum inhibitory concentration (MIC)	1015:1052	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	3	67	theme	electron	466:473	arg1	observation					496:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	7	68	theme	composite	986:994	arg1	activity					962:969	The antibacterial activity	944:969	The antibacterial activity of the BC-PGPE composite	944:994	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	3	69	theme	Field-emission	442:455	arg1	observation					496:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation	442:506	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	0	70	theme	bacterial	24:32	arg1	cellulose-pomegranate					34:54	low-cost bacterial cellulose-pomegranate	15:54	low-cost bacterial cellulose-pomegranate	15:54	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	8	71	dep	both	1274:1277	arg1	form					1286:1289	the form	1282:1289	the form of extract	1282:1300	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	11	72	theme	BC-PGPE	1667:1673	arg1	composite					1675:1683	BC-PGPE composite	1667:1683	BC-PGPE composite	1667:1683	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	11	72	theme	BC-PGPE	1667:1673	arg1	material					1735:1742	a promising antibacterial wound dressing material	1694:1742	a promising antibacterial wound dressing material	1694:1742	The findings of this study indicate that BC-PGPE composite could be a promising antibacterial wound dressing material.					
36649873	1	73	theme	biomedical	306:315	arg1	applications					317:328	potential biomedical applications	296:328	potential biomedical applications	296:328	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	74	with	composite	224:232	arg1	extract					277:283	pomegranate (Punica granatum L.) peel extract	239:283	pomegranate (Punica granatum L.) peel extract (PGPE)	239:290	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	74	with	composite	224:232	arg1	Punica					252:257	Punica	252:257	Punica	252:257	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	1	74	with	composite	224:232	arg1	PGPE					286:289	PGPE	286:289	PGPE	286:289	This study was aimed to develop low-cost bacterial cellulose (BC)-based antibacterial composite with pomegranate (Punica granatum L.) peel extract (PGPE) for potential biomedical applications.					
36649873	8	75	dep	coli	1252:1255	arg1	Gram-negative					1258:1270	Gram-negative	1258:1270	Gram-negative	1258:1270	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	0	76	theme	antibacterial	75:87	arg1	composite					89:97	extract-based antibacterial composite	61:97	extract-based antibacterial composite for potential biomedical applications	61:135	Development of low-cost bacterial cellulose-pomegranate peel extract-based antibacterial composite for potential biomedical applications.					
36649873	9	77	theme	BC-PGPE	1381:1387	arg1	composite					1389:1397	The BC-PGPE composite	1377:1397	The BC-PGPE composite	1377:1397	The BC-PGPE composite produced a 17 mm zone of inhibition against S. aureus, while no inhibition zone was formed against E. coli.					
36649873	7	78	theme	disc	1097:1100	arg1	diffusion					1102:1110	disc diffusion	1097:1110	disc diffusion	1097:1110	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	3	79	theme	nanofibrous	517:527	arg1	morphology					545:554	a nanofibrous and microporous morphology	515:554	a nanofibrous and microporous morphology of pristine BC	515:569	Field-emission scanning electron microscopic (FE-SEM) observation showed a nanofibrous and microporous morphology of pristine BC and confirmed the development of BC-PGPE composite.					
36649873	7	80	theme	antibacterial	948:960	arg1	activity					962:969	The antibacterial activity	944:969	The antibacterial activity of the BC-PGPE composite	944:994	The antibacterial activity of the BC-PGPE composite was determined via minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), disc diffusion, and plate count methods.					
36649873	6	81	theme	reswelling	860:869	arg1	capabilities					871:882	better reswelling capabilities	853:882	better reswelling capabilities	853:882	The BC-PGPE composite exhibited better reswelling capabilities than pristine BC after three consecutive re-wetting cycles.					
36649873	9	82	theme	17 mm	1410:1414	arg1	zone					1416:1419	a 17 mm zone	1408:1419	a 17 mm zone of inhibition against S. aureus	1408:1451	The BC-PGPE composite produced a 17 mm zone of inhibition against S. aureus, while no inhibition zone was formed against E. coli.					
36649873	8	83	theme	good	1162:1165	arg1	activity					1181:1188	good antimicrobial activity	1162:1188	good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC	1162:1322	The PGPE extract showed good antimicrobial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative), both in the form of extract and composite with BC, with relatively better activity against the former.					
36649873	10	84	from	reduction	1562:1570	arg1	growth					1579:1584	the growth	1575:1584	the growth of S. aureus and E. coli	1575:1609	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
36649873	10	85	theme	%	1551:1551	arg1	reduction					1562:1570	a 100 % and 50 % reduction	1545:1570	a 100 % and 50 % reduction in the growth of S. aureus and E. coli	1545:1609	Furthermore, BC-PGPE composite caused a 100 % and 50 % reduction in the growth of S. aureus and E. coli, respectively.					
35988977	6	0	theme	-151	822:825	arg1	K					803:803	K	803:803	K	803:803	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
35988977	6	0	theme	-151	822:825	arg1	enthalpy					810:817	enthalpy	810:817	enthalpy of -151 and -95.5 kJ/mol	810:842	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
35988977	2	1	with	coacervation	296:307	arg1	SPP					409:411	SPP	409:411	SPP	409:411	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	1	with	coacervation	296:307	arg1	protein					400:406	soluble pea protein	388:406	soluble pea protein (SPP)	388:412	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	8	2	theme	new	1040:1042	arg1	alternatives					1044:1055	new alternatives	1040:1055	new alternatives for encapsulation of bioactive compounds	1040:1096	GA1 resulted in stronger interactions with SPP, offering new alternatives for encapsulation of bioactive compounds.					
35988977	2	3	theme	complex	288:294	arg1	coacervation					296:307	the complex coacervation	284:307	the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP)	284:412	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	4	dep	arabic	329:334	arg1	senegal-GA1					349:359	Acacia senegal-GA1	342:359	Acacia senegal-GA1	342:359	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	4	dep	arabic	329:334	arg1	seyal-GA2					372:380	Acacia seyal-GA2	365:380	Acacia seyal-GA2	365:380	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	0	5	theme	complex	72:78	arg1	coacervation					80:91	complex coacervation	72:91	complex coacervation	72:91	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	5	6	theme	0.7	784:786	arg1	Entropy					773:779	Entropy	773:779	Entropy of 0.7 and 0.5 kJ/mol.	773:802	Entropy of 0.7 and 0.5 kJ/mol.					
35988977	2	7	theme	secondary	465:473	arg1	structure					475:483	the secondary structure	461:483	the secondary structure of SPP	461:490	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	3	8	theme	SPP	665:667	arg1	structure					652:660	the secondary structure	638:660	the secondary structure of SPP	638:667	The maximum formation of coacervates occurred at SPP:GA 3:1 (w/w) and pH 3.5-4.0 with changes in the secondary structure of SPP.					
35988977	7	9	theme	energy	975:980	arg1	values					950:955	the negative values	937:955	the negative values of the Gibbs free energy	937:980	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	4	10	theme	GA1	670:672	arg1	combination					674:684	GA1 combination	670:684	GA1 combination	670:684	GA1 combination resulted in higher binding constant, implying a stronger affinity between SPP and GA1.					
35988977	1	11	theme	charged	168:174	arg1	biopolymers					176:186	two oppositely charged biopolymers	153:186	two oppositely charged biopolymers	153:186	Complex coacervation is an encapsulation process involving two oppositely charged biopolymers.					
35988977	3	12	theme	secondary	642:650	arg1	structure					652:660	the secondary structure	638:660	the secondary structure of SPP	638:667	The maximum formation of coacervates occurred at SPP:GA 3:1 (w/w) and pH 3.5-4.0 with changes in the secondary structure of SPP.					
35988977	4	13	theme	binding	705:711	arg1	constant					713:720	higher binding constant	698:720	higher binding constant	698:720	GA1 combination resulted in higher binding constant, implying a stronger affinity between SPP and GA1.					
35988977	2	14	theme	Acacia	365:370	arg1	seyal-GA2					372:380	Acacia seyal-GA2	365:380	Acacia seyal-GA2	365:380	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	7	15	theme	Gibbs	964:968	arg1	energy					975:980	the Gibbs free energy	960:980	the Gibbs free energy	960:980	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	2	16	theme	types	316:320	arg1	coacervation					296:307	the complex coacervation	284:307	the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP)	284:412	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	5	17	theme	0.5 kJ/mol	792:801	arg1	Entropy					773:779	Entropy	773:779	Entropy of 0.7 and 0.5 kJ/mol.	773:802	Entropy of 0.7 and 0.5 kJ/mol.					
35988977	7	18	theme	free	970:973	arg1	energy					975:980	the Gibbs free energy	960:980	the Gibbs free energy	960:980	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	0	19	theme	gum	12:14	arg1	arabic					16:21	gum arabic	12:21	gum arabic	12:21	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	4	20	theme	stronger	734:741	arg1	affinity					743:750	a stronger affinity	732:750	a stronger affinity between SPP and GA1	732:770	GA1 combination resulted in higher binding constant, implying a stronger affinity between SPP and GA1.					
35988977	3	21	theme	maximum	545:551	arg1	formation					553:561	The maximum formation	541:561	The maximum formation of coacervates	541:576	The maximum formation of coacervates occurred at SPP:GA 3:1 (w/w) and pH 3.5-4.0 with changes in the secondary structure of SPP.					
35988977	8	22	with	interactions	1008:1019	arg1	SPP					1026:1028	SPP	1026:1028	SPP	1026:1028	GA1 resulted in stronger interactions with SPP, offering new alternatives for encapsulation of bioactive compounds.					
35988977	2	23	theme	pea	396:398	arg1	SPP					409:411	SPP	409:411	SPP	409:411	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	23	theme	pea	396:398	arg1	protein					400:406	soluble pea protein	388:406	soluble pea protein (SPP)	388:412	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	8	24	theme	bioactive	1078:1086	arg1	compounds					1088:1096	bioactive compounds	1078:1096	bioactive compounds	1078:1096	GA1 resulted in stronger interactions with SPP, offering new alternatives for encapsulation of bioactive compounds.					
35988977	2	25	theme	UV/vis	493:498	arg1	absorbance					500:509	UV/vis absorbance	493:509	UV/vis absorbance	493:509	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	1	26	theme	Complex	94:100	arg1	coacervation					102:113	Complex coacervation	94:113	Complex coacervation	94:113	Complex coacervation is an encapsulation process involving two oppositely charged biopolymers.					
35988977	1	26	theme	Complex	94:100	arg1	process					135:141	an encapsulation process	118:141	an encapsulation process involving two oppositely charged biopolymers	118:186	Complex coacervation is an encapsulation process involving two oppositely charged biopolymers.					
35988977	2	27	theme	soluble	388:394	arg1	SPP					409:411	SPP	409:411	SPP	409:411	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	27	theme	soluble	388:394	arg1	protein					400:406	soluble pea protein	388:406	soluble pea protein (SPP)	388:412	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	7	28	theme	negative	941:948	arg1	values					950:955	the negative values	937:955	the negative values of the Gibbs free energy	937:980	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	0	29	from	protein	61:67	arg1	coacervation					80:91	complex coacervation	72:91	complex coacervation	72:91	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	0	30	theme	arabic	16:21	arg1	type					4:7	The type	0:7	The type of gum arabic	0:21	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	3	31	from	changes	627:633	arg1	structure					652:660	the secondary structure	638:660	the secondary structure of SPP	638:667	The maximum formation of coacervates occurred at SPP:GA 3:1 (w/w) and pH 3.5-4.0 with changes in the secondary structure of SPP.					
35988977	2	32	theme	SPP	488:490	arg1	structure					475:483	the secondary structure	461:483	the secondary structure of SPP	461:490	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	32	theme	SPP	488:490	arg1	turbidity					438:446	turbidity	438:446	turbidity	438:446	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	32	theme	SPP	488:490	arg1	parameters					529:538	thermodynamic parameters	515:538	thermodynamic parameters	515:538	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	32	theme	SPP	488:490	arg1	morphology					449:458	morphology	449:458	morphology	449:458	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	32	theme	SPP	488:490	arg1	absorbance					500:509	UV/vis absorbance	493:509	UV/vis absorbance	493:509	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	32	theme	SPP	488:490	arg1	potential					427:435	Zeta potential	422:435	Zeta potential	422:435	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	8	33	theme	compounds	1088:1096	arg1	encapsulation					1061:1073	encapsulation	1061:1073	encapsulation of bioactive compounds	1061:1096	GA1 resulted in stronger interactions with SPP, offering new alternatives for encapsulation of bioactive compounds.					
35988977	2	34	theme	Zeta	422:425	arg1	potential					427:435	Zeta potential	422:435	Zeta potential	422:435	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	35	with	interaction	247:257	arg1	protein					264:270	protein	264:270	protein	264:270	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	8	36	theme	stronger	999:1006	arg1	interactions					1008:1019	stronger interactions	999:1019	stronger interactions with SPP	999:1028	GA1 resulted in stronger interactions with SPP, offering new alternatives for encapsulation of bioactive compounds.					
35988977	6	37	dep	GA2	878:880	arg1	GA1					866:868	GA1	866:868	GA1	866:868	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
35988977	6	37	dep	GA2	878:880	arg1	SPP					874:876	SPP	874:876	SPP	874:876	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
35988977	2	38	theme	gum	221:223	arg1	arabic					225:230	gum arabic	221:230	gum arabic	221:230	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	39	theme	arabic	225:230	arg1	compositions					205:216	different compositions	195:216	different compositions of gum arabic	195:230	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	7	40	theme	complex	887:893	arg1	coacervation					895:906	The complex coacervation	883:906	The complex coacervation	883:906	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	7	40	theme	complex	887:893	arg1	spontaneous					912:922	spontaneous	912:922	spontaneous	912:922	The complex coacervation was spontaneous as proved by the negative values of the Gibbs free energy.					
35988977	2	41	theme	arabic	329:334	arg1	types					316:320	two types	312:320	two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2)	312:381	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	42	theme	thermodynamic	515:527	arg1	parameters					529:538	thermodynamic parameters	515:538	thermodynamic parameters	515:538	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	43	theme	gum	325:327	arg1	arabic					329:334	gum arabic	325:334	gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2)	325:381	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	2	43	theme	gum	325:327	arg1	GA					337:338	GA	337:338	GA	337:338	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	4	44	theme	higher	698:703	arg1	constant					713:720	higher binding constant	698:720	higher binding constant	698:720	GA1 combination resulted in higher binding constant, implying a stronger affinity between SPP and GA1.					
35988977	1	45	theme	encapsulation	121:133	arg1	coacervation					102:113	Complex coacervation	94:113	Complex coacervation	94:113	Complex coacervation is an encapsulation process involving two oppositely charged biopolymers.					
35988977	1	45	theme	encapsulation	121:133	arg1	process					135:141	an encapsulation process	118:141	an encapsulation process involving two oppositely charged biopolymers	118:186	Complex coacervation is an encapsulation process involving two oppositely charged biopolymers.					
35988977	0	46	theme	pea	57:59	arg1	protein					61:67	soluble pea protein	49:67	soluble pea protein in complex coacervation	49:91	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	2	47	theme	different	195:203	arg1	compositions					205:216	different compositions	195:216	different compositions of gum arabic	195:230	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	3	48	theme	coacervates	566:576	arg1	formation					553:561	The maximum formation	541:561	The maximum formation of coacervates	541:576	The maximum formation of coacervates occurred at SPP:GA 3:1 (w/w) and pH 3.5-4.0 with changes in the secondary structure of SPP.					
35988977	0	49	with	interactions	31:42	arg1	protein					61:67	soluble pea protein	49:67	soluble pea protein in complex coacervation	49:91	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	2	50	theme	Acacia	342:347	arg1	senegal-GA1					349:359	Acacia senegal-GA1	342:359	Acacia senegal-GA1	342:359	Since different compositions of gum arabic may affect its interaction with protein, we studied the complex coacervation of two types of gum arabic (GA) (Acacia senegal-GA1 and Acacia seyal-GA2) with soluble pea protein (SPP) through Zeta potential, turbidity, morphology, the secondary structure of SPP, UV/vis absorbance and thermodynamic parameters.					
35988977	0	51	theme	soluble	49:55	arg1	protein					61:67	soluble pea protein	49:67	soluble pea protein in complex coacervation	49:91	The type of gum arabic affects interactions with soluble pea protein in complex coacervation.					
35988977	6	52	theme	-95.5 kJ/mol	831:842	arg1	K					803:803	K	803:803	K	803:803	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
35988977	6	52	theme	-95.5 kJ/mol	831:842	arg1	enthalpy					810:817	enthalpy	810:817	enthalpy of -151 and -95.5 kJ/mol	810:842	K, and enthalpy of -151 and -95.5 kJ/mol were obtained for SPP:GA1 and SPP:GA2.					
36526855	7	0	from	contrast	1159:1166	arg1	prothrombin					1226:1236	the prothrombin	1222:1236	the prothrombin of the shark	1222:1249	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	0	from	contrast	1159:1166	arg1	N-glycosylated					1261:1274	N-glycosylated	1261:1274	N-glycosylated	1261:1274	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	8	1	theme	coagulation	1361:1371	arg1	factors					1373:1379	blood coagulation factors	1355:1379	blood coagulation factors in a cartilaginous fish	1355:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	5	2	theme	shark	826:830	arg1	prothrombin					832:842	the shark prothrombin	822:842	the shark prothrombin	822:842	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	1	3	theme	system	250:255	arg1	Prothrombin					182:192	Prothrombin	182:192	Prothrombin	182:192	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	1	3	theme	system	250:255	arg1	precursor					215:223	a serine protease precursor	197:223	a serine protease precursor of the blood coagulation system	197:255	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	7	4	gly	N-glycosylated	1261:1274	arg1	prothrombin					1226:1236	the prothrombin	1222:1236	the prothrombin of the shark	1222:1249	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	4	gly	N-glycosylated	1261:1274	arg2	N-glycosylated					1261:1274	N-glycosylated	1261:1274	N-glycosylated	1261:1274	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	4	gly	N-glycosylated	1261:1274	arg1	N-glycosylated					1261:1274	N-glycosylated	1261:1274	N-glycosylated	1261:1274	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	4	gly	N-glycosylated	1261:1274	arg1	contrast					1159:1166	contrast	1159:1166	contrast	1159:1166	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	4	gly	N-glycosylated	1261:1274	arg2	prothrombin					1226:1236	the prothrombin	1222:1236	the prothrombin of the shark	1222:1249	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	0	5	from	properties	7:16	arg1	japonicus					68:76	the bullhead shark Heterodontus japonicus	36:76	the bullhead shark Heterodontus japonicus	36:76	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	8	6	theme	blood	1355:1359	arg1	factors					1373:1379	blood coagulation factors	1355:1379	blood coagulation factors in a cartilaginous fish	1355:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	6	7	from	121st	980:984	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	2	8	theme	bullhead	335:342	arg1	fish					329:332	a cartilaginous fish	313:332	a cartilaginous fish	313:332	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	2	8	theme	bullhead	335:342	arg1	shark					344:348	bullhead shark	335:348	bullhead shark (Heterodontus japonicus)	335:373	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	2	8	theme	bullhead	335:342	arg1	japonicus					364:372	Heterodontus japonicus	351:372	Heterodontus japonicus	351:372	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	2	9	theme	primary	277:283	arg1	structure					285:293	the primary structure	273:293	the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus),	273:374	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	0	10	theme	first	83:87	arg1	report					89:94	the first report	79:94	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	6	11	from	179th	987:991	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	5	12	theme	amino	889:893	arg1	sequence					900:907	its amino acid sequence	885:907	its amino acid sequence	885:907	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	4	13	theme	acid	667:670	arg1	sequence					672:679	the amino acid sequence	657:679	the amino acid sequence of the shark prothrombin	657:704	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	0	14	theme	purification	99:110	arg1	report					89:94	the first report	79:94	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	4	15	theme	amino	661:665	arg1	sequence					672:679	the amino acid sequence	657:679	the amino acid sequence of the shark prothrombin	657:704	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	5	16	theme	acid	895:898	arg1	sequence					900:907	its amino acid sequence	885:907	its amino acid sequence	885:907	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	5	17	theme	molecular	804:812	arg1	110 kDa					860:866	110 kDa	860:866	110 kDa	860:866	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	5	17	theme	molecular	804:812	arg1	mass					814:817	The apparent molecular mass	791:817	The apparent molecular mass of the shark prothrombin on SDS-PAGE	791:854	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	7	18	theme	7-kDa	1205:1209	arg1	N-glycans					1211:1219	only 7-kDa N-glycans	1200:1219	only 7-kDa N-glycans	1200:1219	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	4	19	located	found	648:652	arg2	residues					589:596	Two arginine residues	576:596	Two arginine residues that should be cleaved by activated factor X	576:641	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	4	19	located	found	648:652	arg1	sequence					672:679	the amino acid sequence	657:679	the amino acid sequence of the shark prothrombin	657:704	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	4	20	theme	cleavage	731:738	arg1	sites					740:744	the two cleavage sites	723:744	the two cleavage sites for thrombin or meizothrombin	723:774	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	6	21	from	79th	967:970	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	8	22	from	characterization	1335:1350	arg1	fish					1400:1403	a cartilaginous fish	1384:1403	a cartilaginous fish	1384:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	5	23	theme	apparent	795:802	arg1	110 kDa					860:866	110 kDa	860:866	110 kDa	860:866	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	5	23	theme	apparent	795:802	arg1	mass					814:817	The apparent molecular mass	791:817	The apparent molecular mass of the shark prothrombin on SDS-PAGE	791:854	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	5	24	theme	prothrombin	832:842	arg1	110 kDa					860:866	110 kDa	860:866	110 kDa	860:866	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	5	24	theme	prothrombin	832:842	arg1	mass					814:817	The apparent molecular mass	791:817	The apparent molecular mass of the shark prothrombin on SDS-PAGE	791:854	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	6	25	theme	shark	1045:1049	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	8	26	theme	cartilaginous	1386:1398	arg1	fish					1400:1403	a cartilaginous fish	1384:1403	a cartilaginous fish	1384:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	4	27	theme	factor	634:639	arg1	X					641:641	activated factor X	624:641	activated factor X	624:641	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	0	28	theme	Unique	0:5	arg1	properties					7:16	Unique properties	0:16	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	6	29	from	108th	973:977	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	2	30	theme	prothrombin	298:308	arg1	structure					285:293	the primary structure	273:293	the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus),	273:374	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	6	31	theme	Potential	921:929	arg1	sites					947:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	4	32	theme	activated	624:632	arg1	X					641:641	activated factor X	624:641	activated factor X	624:641	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	0	33	theme	prothrombin	21:31	arg1	properties					7:16	Unique properties	0:16	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	3	34	theme	homologues	564:573	arg1	case					537:540	the case	533:540	the case of reported mammalian homologues	533:573	Bullhead shark prothrombin was found to be comprised of four domains, as in the case of reported mammalian homologues.					
36526855	0	35	theme	characterization	116:131	arg1	report					89:94	the first report	79:94	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	7	36	theme	shark	1245:1249	arg1	prothrombin					1226:1236	the prothrombin	1222:1236	the prothrombin of the shark	1222:1249	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	36	theme	shark	1245:1249	arg1	N-glycosylated					1261:1274	N-glycosylated	1261:1274	N-glycosylated	1261:1274	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	4	37	theme	prothrombin	694:704	arg1	sequence					672:679	the amino acid sequence	657:679	the amino acid sequence of the shark prothrombin	657:704	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	6	38	from	residues	1029:1036	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	5	39	from	mass	814:817	arg1	SDS-PAGE					847:854	SDS-PAGE	847:854	SDS-PAGE	847:854	The apparent molecular mass of the shark prothrombin on SDS-PAGE was 110 kDa, whereas that of its amino acid sequence was 65 kDa.					
36526855	6	40	with	treatment	1068:1076	arg1	N-glycosidase					1083:1095	N-glycosidase	1083:1095	N-glycosidase	1083:1095	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	4	41	theme	shark	688:692	arg1	prothrombin					694:704	the shark prothrombin	684:704	the shark prothrombin	684:704	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	1	42	theme	serine	199:204	arg1	Prothrombin					182:192	Prothrombin	182:192	Prothrombin	182:192	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	1	42	theme	serine	199:204	arg1	precursor					215:223	a serine protease precursor	197:223	a serine protease precursor of the blood coagulation system	197:255	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	6	43	theme	527th	1012:1016	arg1	residues					1029:1036	527th asparagine residues	1012:1036	527th asparagine residues in the shark prothrombin	1012:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	7	44	theme	human	1171:1175	arg1	prothrombin					1177:1187	human prothrombin	1171:1187	human prothrombin	1171:1187	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	3	45	theme	reported	545:552	arg1	homologues					564:573	reported mammalian homologues	545:573	reported mammalian homologues	545:573	Bullhead shark prothrombin was found to be comprised of four domains, as in the case of reported mammalian homologues.					
36526855	1	46	theme	protease	206:213	arg1	Prothrombin					182:192	Prothrombin	182:192	Prothrombin	182:192	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	1	46	theme	protease	206:213	arg1	precursor					215:223	a serine protease precursor	197:223	a serine protease precursor of the blood coagulation system	197:255	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	2	47	theme	blood	443:447	arg1	plasma					449:454	the blood plasma	439:454	the blood plasma	439:454	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	8	48	dep	purification	1318:1329	arg1	the					1314:1316	the	1314:1316	the	1314:1316	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	3	49	theme	mammalian	554:562	arg1	homologues					564:573	reported mammalian homologues	545:573	reported mammalian homologues	545:573	Bullhead shark prothrombin was found to be comprised of four domains, as in the case of reported mammalian homologues.					
36526855	0	50	theme	shark	49:53	arg1	japonicus					68:76	the bullhead shark Heterodontus japonicus	36:76	the bullhead shark Heterodontus japonicus	36:76	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	0	51	theme	coagulation	144:154	arg1	factor					156:161	a blood coagulation factor	136:161	a blood coagulation factor	136:161	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	6	52	located	found	958:962	arg1	79th					967:970	79th	967:970	79th	967:970	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	108th					973:977	108th	973:977	108th	973:977	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	199th					994:998	199th	994:998	199th	994:998	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	residues					1029:1036	527th asparagine residues	1012:1036	527th asparagine residues in the shark prothrombin	1012:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	507th					1001:1005	507th	1001:1005	507th	1001:1005	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	121st					980:984	121st	980:984	121st	980:984	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg2	sites					947:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	52	located	found	958:962	arg1	179th					987:991	179th	987:991	179th	987:991	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	3	53	theme	shark	466:470	arg1	prothrombin					472:482	Bullhead shark prothrombin	457:482	Bullhead shark prothrombin	457:482	Bullhead shark prothrombin was found to be comprised of four domains, as in the case of reported mammalian homologues.					
36526855	0	54	theme	bullhead	40:47	arg1	japonicus					68:76	the bullhead shark Heterodontus japonicus	36:76	the bullhead shark Heterodontus japonicus	36:76	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	8	55	from	fish	1400:1403	arg1	characterization					1335:1350	characterization	1335:1350	characterization	1335:1350	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	8	55	from	fish	1400:1403	arg1	purification					1318:1329	purification	1318:1329	purification	1318:1329	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	0	56	theme	blood	138:142	arg1	factor					156:161	a blood coagulation factor	136:161	a blood coagulation factor	136:161	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	6	57	theme	molecular	1109:1117	arg1	mass					1119:1122	the molecular mass	1105:1122	the molecular mass to 65 kDa	1105:1132	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	2	58	theme	fish	329:332	arg1	prothrombin					298:308	prothrombin	298:308	prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus),	298:374	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	7	59	from	N-glycosylated	1261:1274	arg1	contrast					1159:1166	contrast	1159:1166	contrast	1159:1166	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	60	contain	has	1196:1198	arg2	N-glycans					1211:1219	only 7-kDa N-glycans	1200:1219	only 7-kDa N-glycans	1200:1219	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	7	60	contain	has	1196:1198	arg1	contrast					1159:1166	contrast	1159:1166	contrast	1159:1166	This indicates that, in contrast to human prothrombin, which has only 7-kDa N-glycans, the prothrombin of the shark is highly N-glycosylated.					
36526855	4	61	theme	sites	740:744	arg1	sites					740:744	the two cleavage sites	723:744	the two cleavage sites for thrombin or meizothrombin	723:774	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	4	61	theme	sites	740:744	arg1	one					716:718	one	716:718	one	716:718	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	2	62	theme	cartilaginous	315:327	arg1	fish					329:332	a cartilaginous fish	313:332	a cartilaginous fish	313:332	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	2	62	theme	cartilaginous	315:327	arg1	shark					344:348	bullhead shark	335:348	bullhead shark (Heterodontus japonicus)	335:373	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	6	63	from	507th	1001:1005	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	0	64	theme	factor	156:161	arg1	characterization					116:131	characterization	116:131	characterization	116:131	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	0	64	theme	factor	156:161	arg1	purification					99:110	purification	99:110	purification	99:110	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	0	65	from	report	89:94	arg1	Chondrichthyes					166:179	Chondrichthyes	166:179	Chondrichthyes	166:179	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	6	66	from	199th	994:998	arg1	prothrombin					1051:1061	the shark prothrombin	1041:1061	the shark prothrombin	1041:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	3	67	theme	Bullhead	457:464	arg1	prothrombin					472:482	Bullhead shark prothrombin	457:482	Bullhead shark prothrombin	457:482	Bullhead shark prothrombin was found to be comprised of four domains, as in the case of reported mammalian homologues.					
36526855	6	68	theme	asparagine	1018:1027	arg1	residues					1029:1036	527th asparagine residues	1012:1036	527th asparagine residues in the shark prothrombin	1012:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	8	69	from	purification	1318:1329	arg1	fish					1400:1403	a cartilaginous fish	1384:1403	a cartilaginous fish	1384:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	8	70	from	factors	1373:1379	arg1	fish					1400:1403	a cartilaginous fish	1384:1403	a cartilaginous fish	1384:1403	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	0	71	dep	properties	7:16	arg1	report					89:94	the first report	79:94	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.	0:180	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	4	72	theme	arginine	580:587	arg1	residues					589:596	Two arginine residues	576:596	Two arginine residues that should be cleaved by activated factor X	576:641	Two arginine residues that should be cleaved by activated factor X were found in the amino acid sequence of the shark prothrombin, but only one of the two cleavage sites for thrombin or meizothrombin was conserved.					
36526855	2	73	theme	Heterodontus	351:362	arg1	shark					344:348	bullhead shark	335:348	bullhead shark (Heterodontus japonicus)	335:373	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	2	73	theme	Heterodontus	351:362	arg1	japonicus					364:372	Heterodontus japonicus	351:372	Heterodontus japonicus	351:372	In this study, the primary structure of prothrombin of a cartilaginous fish, bullhead shark (Heterodontus japonicus), was determined using RNA-Seq and the protein was purified from the blood plasma.					
36526855	1	74	theme	blood	232:236	arg1	system					250:255	the blood coagulation system	228:255	the blood coagulation system	228:255	Prothrombin is a serine protease precursor of the blood coagulation system.					
36526855	0	75	theme	Heterodontus	55:66	arg1	japonicus					68:76	the bullhead shark Heterodontus japonicus	36:76	the bullhead shark Heterodontus japonicus	36:76	Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes.					
36526855	8	76	theme	factors	1373:1379	arg1	characterization					1335:1350	characterization	1335:1350	characterization	1335:1350	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	8	76	theme	factors	1373:1379	arg1	purification					1318:1329	purification	1318:1329	purification	1318:1329	This study is the first to report on the purification and characterization of blood coagulation factors in a cartilaginous fish.					
36526855	6	77	theme	N-glycosylation	931:945	arg1	sites					947:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	121st					980:984	121st	980:984	121st	980:984	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	507th					1001:1005	507th	1001:1005	507th	1001:1005	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	179th					987:991	179th	987:991	179th	987:991	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	residues					1029:1036	527th asparagine residues	1012:1036	527th asparagine residues in the shark prothrombin	1012:1061	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	79th					967:970	79th	967:970	79th	967:970	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	sites					947:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites	921:951	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	108th					973:977	108th	973:977	108th	973:977	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	6	78	gly	N-glycosylation	931:945	arg2	199th					994:998	199th	994:998	199th	994:998	Potential N-glycosylation sites were found at 79th, 108th, 121st, 179th, 199th, 507th, and 527th asparagine residues in the shark prothrombin, and treatment with N-glycosidase reduced the molecular mass to 65 kDa.					
36526855	1	79	theme	coagulation	238:248	arg1	system					250:255	the blood coagulation system	228:255	the blood coagulation system	228:255	Prothrombin is a serine protease precursor of the blood coagulation system.					
35605720	0	0	theme	surface	93:99	arg1	methodology					101:111	response surface methodology	84:111	response surface methodology for food packaging applications	84:143	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	2	1	theme	Aloe	494:497	arg1	vera					499:502	Aloe vera	494:502	Aloe vera (AV)	494:507	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	2	1	theme	Aloe	494:497	arg1	AV					505:506	AV	505:506	AV	505:506	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	8	2	used	used	1455:1458	arg2	it					1443:1444	it	1443:1444	it	1443:1444	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	5	3	dep	permeability	975:986	arg1	water					963:967	alginate's thermal, water vapor permeability	943:986	water	963:967	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	0	4	theme	response	84:91	arg1	methodology					101:111	response surface methodology	84:111	response surface methodology for food packaging applications	84:143	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	8	5	theme	film	1437:1440	arg1	properties					1389:1398	the outstanding physical, UV-shielding, and antimicrobial properties	1331:1398	the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film	1331:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	1	6	theme	alginate	189:196	arg1	characteristics					170:184	the outstanding characteristics	154:184	the outstanding characteristics of alginate	154:196	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	8	7	theme	antimicrobial	1375:1387	arg1	properties					1389:1398	the outstanding physical, UV-shielding, and antimicrobial properties	1331:1398	the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film	1331:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	2	8	theme	zinc	513:516	arg1	oxide					518:522	zinc oxide	513:522	zinc oxide	513:522	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	5	9	theme	ZnO-NPs	912:918	arg1	incorporation					883:895	The incorporation	879:895	The incorporation of both AV and ZnO-NPs	879:918	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	10	theme	thermal	954:960	arg1	permeability					975:986	alginate's thermal, water vapor permeability	943:986	permeability	975:986	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	10	theme	thermal	954:960	arg1	properties					1024:1033	mechanical and antimicrobial properties	995:1033	mechanical and antimicrobial properties	995:1033	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	10	theme	thermal	954:960	arg1	WVP					989:991	WVP	989:991	WVP	989:991	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	8	11	theme	UV-shielding	1357:1368	arg1	properties					1389:1398	the outstanding physical, UV-shielding, and antimicrobial properties	1331:1398	the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film	1331:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	4	12	used	used	814:817	arg2	XRD					805:807	XRD	805:807	XRD	805:807	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	4	12	used	used	814:817	arg2	diffraction					792:802	the wide-angle X-ray diffraction	771:802	the wide-angle X-ray diffraction (XRD)	771:808	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	1	13	theme	wide	288:291	arg1	usage					293:297	its wide usage	284:297	its wide usage in food packaging	284:315	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	0	14	theme	packaging	122:130	arg1	applications					132:143	food packaging applications	117:143	food packaging applications	117:143	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	5	15	theme	antimicrobial	1010:1022	arg1	properties					1024:1033	mechanical and antimicrobial properties	995:1033	mechanical and antimicrobial properties	995:1033	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	15	theme	antimicrobial	1010:1022	arg1	permeability					975:986	alginate's thermal, water vapor permeability	943:986	permeability	975:986	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	4	16	theme	wide-angle	775:784	arg1	XRD					805:807	XRD	805:807	XRD	805:807	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	4	16	theme	wide-angle	775:784	arg1	diffraction					792:802	the wide-angle X-ray diffraction	771:802	the wide-angle X-ray diffraction (XRD)	771:808	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	7	17	theme	fruits	1282:1287	arg1	shelf-life					1261:1270	the shelf-life	1257:1270	the shelf-life of tomato fruits	1257:1287	The optimized alginate film incorporated with both ZnO-NPs and AV significantly extended the shelf-life of tomato fruits up to 16 days without any defects.					
35605720	2	18	theme	alginate-based	387:400	arg1	coating					409:415	an alginate-based edible coating	384:415	an alginate-based edible coating of the best optimized UV-shielding properties	384:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	0	19	theme	food	117:120	arg1	applications					132:143	food packaging applications	117:143	food packaging applications	117:143	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	8	20	theme	food	1475:1478	arg1	industries					1490:1499	food packaging industries	1475:1499	food packaging industries	1475:1499	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	5	21	theme	AV	905:906	arg1	incorporation					883:895	The incorporation	879:895	The incorporation of both AV and ZnO-NPs	879:918	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	7	22	theme	tomato	1275:1280	arg1	fruits					1282:1287	tomato fruits	1275:1287	tomato fruits	1275:1287	The optimized alginate film incorporated with both ZnO-NPs and AV significantly extended the shelf-life of tomato fruits up to 16 days without any defects.					
35605720	2	23	theme	properties	452:461	arg1	coating					409:415	an alginate-based edible coating	384:415	an alginate-based edible coating of the best optimized UV-shielding properties	384:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	3	24	theme	ZnO-NPs	669:675	arg1	compositions					617:628	the optimized compositions	603:628	the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%)	603:686	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	1	25	from	usage	293:297	arg1	packaging					307:315	food packaging	302:315	food packaging	302:315	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	2	26	theme	UV-shielding	439:450	arg1	properties					452:461	the best optimized UV-shielding properties	420:461	the best optimized UV-shielding properties	420:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	4	27	theme	X-ray	786:790	arg1	XRD					805:807	XRD	805:807	XRD	805:807	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	4	27	theme	X-ray	786:790	arg1	diffraction					792:802	the wide-angle X-ray diffraction	771:802	the wide-angle X-ray diffraction (XRD)	771:808	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	3	28	theme	optimized	553:561	arg1	UV-transmittance					571:586	The optimized minimum UV-transmittance	549:586	The optimized minimum UV-transmittance	549:586	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	3	28	theme	optimized	553:561	arg1	%					596:596	4.96%	592:596	4.96%	592:596	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	0	29	theme	edible	30:35	arg1	coatings					37:44	alginate-based edible coatings	15:44	alginate-based edible coatings of optimized UV-barrier properties	15:79	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	6	30	theme	UV-barrier	1117:1126	arg1	properties					1128:1137	excellent UV-barrier properties	1107:1137	excellent UV-barrier properties	1107:1137	In addition, the films incorporated with both AV and ZnO-NPs exhibited excellent UV-barrier properties compared with neat alginate.					
35605720	5	31	theme	mechanical	995:1004	arg1	properties					1024:1033	mechanical and antimicrobial properties	995:1033	mechanical and antimicrobial properties	995:1033	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	31	theme	mechanical	995:1004	arg1	permeability					975:986	alginate's thermal, water vapor permeability	943:986	permeability	975:986	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	1	32	theme	bad	215:217	arg1	UV-barrier					219:228	bad UV-barrier	215:228	bad UV-barrier	215:228	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	0	33	theme	alginate-based	15:28	arg1	coatings					37:44	alginate-based edible coatings	15:44	alginate-based edible coatings of optimized UV-barrier properties	15:79	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	1	34	theme	food	302:305	arg1	packaging					307:315	food packaging	302:315	food packaging	302:315	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	3	35	theme	alginate	633:640	arg1	compositions					617:628	the optimized compositions	603:628	the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%)	603:686	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	7	36	theme	optimized	1172:1180	arg1	film					1191:1194	The optimized alginate film	1168:1194	The optimized alginate film incorporated with both ZnO-NPs and AV	1168:1232	The optimized alginate film incorporated with both ZnO-NPs and AV significantly extended the shelf-life of tomato fruits up to 16 days without any defects.					
35605720	7	37	theme	alginate	1182:1189	arg1	film					1191:1194	The optimized alginate film	1168:1194	The optimized alginate film incorporated with both ZnO-NPs and AV	1168:1232	The optimized alginate film incorporated with both ZnO-NPs and AV significantly extended the shelf-life of tomato fruits up to 16 days without any defects.					
35605720	2	38	theme	nanoparticles	524:536	arg1	incorporation					472:484	the incorporation	468:484	the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs)	468:546	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	8	39	theme	alginate/AV/ZnO-NPs	1417:1435	arg1	film					1437:1440	the optimized alginate/AV/ZnO-NPs film	1403:1440	the optimized alginate/AV/ZnO-NPs film	1403:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	4	40	theme	coating	745:751	arg1	preparation					753:763	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	0	41	theme	coatings	37:44	arg1	Development					0:10	Development	0:10	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.	0:144	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	2	42	theme	oxide	518:522	arg1	ZnO-NPs					539:545	ZnO-NPs	539:545	ZnO-NPs	539:545	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	2	42	theme	oxide	518:522	arg1	nanoparticles					524:536	both Aloe vera (AV) and zinc oxide nanoparticles	489:536	both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs)	489:546	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	3	43	used	used	693:696	arg2	compositions					617:628	the optimized compositions	603:628	the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%)	603:686	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	2	44	theme	optimized	429:437	arg1	properties					452:461	the best optimized UV-shielding properties	420:461	the best optimized UV-shielding properties	420:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	1	45	theme	water	231:235	arg1	barrier					237:243	water barrier	231:243	water barrier	231:243	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	0	46	theme	UV-barrier	59:68	arg1	properties					70:79	optimized UV-barrier properties	49:79	optimized UV-barrier properties	49:79	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	0	47	theme	properties	70:79	arg1	coatings					37:44	alginate-based edible coatings	15:44	alginate-based edible coatings of optimized UV-barrier properties	15:79	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	3	48	theme	minimum	563:569	arg1	UV-transmittance					571:586	The optimized minimum UV-transmittance	549:586	The optimized minimum UV-transmittance	549:586	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	3	48	theme	minimum	563:569	arg1	%					596:596	4.96%	592:596	4.96%	592:596	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	0	49	theme	optimized	49:57	arg1	properties					70:79	optimized UV-barrier properties	49:79	optimized UV-barrier properties	49:79	Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications.					
35605720	8	50	theme	outstanding	1335:1345	arg1	properties					1389:1398	the outstanding physical, UV-shielding, and antimicrobial properties	1331:1398	the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film	1331:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	8	51	theme	optimized	1407:1415	arg1	film					1437:1440	the optimized alginate/AV/ZnO-NPs film	1403:1440	the optimized alginate/AV/ZnO-NPs film	1403:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	5	52	theme	vapor	969:973	arg1	permeability					975:986	alginate's thermal, water vapor permeability	943:986	permeability	975:986	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	52	theme	vapor	969:973	arg1	properties					1024:1033	mechanical and antimicrobial properties	995:1033	mechanical and antimicrobial properties	995:1033	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	5	52	theme	vapor	969:973	arg1	WVP					989:991	WVP	989:991	WVP	989:991	The incorporation of both AV and ZnO-NPs significantly improved alginate's thermal, water vapor permeability (WVP), mechanical and antimicrobial properties.					
35605720	6	53	theme	excellent	1107:1115	arg1	properties					1128:1137	excellent UV-barrier properties	1107:1137	excellent UV-barrier properties	1107:1137	In addition, the films incorporated with both AV and ZnO-NPs exhibited excellent UV-barrier properties compared with neat alginate.					
35605720	3	54	theme	AV	652:653	arg1	compositions					617:628	the optimized compositions	603:628	the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%)	603:686	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	4	55	theme	edible	738:743	arg1	preparation					753:763	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	2	56	theme	Box-Behnken	336:346	arg1	design					348:353	Box-Behnken design	336:353	Box-Behnken design (BBD)	336:359	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	2	56	theme	Box-Behnken	336:346	arg1	BBD					356:358	BBD	356:358	BBD	356:358	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	4	57	used	used	708:711	arg2	FTIR					699:702	FTIR	699:702	FTIR	699:702	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	6	58	theme	neat	1153:1156	arg1	alginate					1158:1165	neat alginate	1153:1165	neat alginate	1153:1165	In addition, the films incorporated with both AV and ZnO-NPs exhibited excellent UV-barrier properties compared with neat alginate.					
35605720	3	59	theme	optimized	607:615	arg1	compositions					617:628	the optimized compositions	603:628	the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%)	603:686	The optimized minimum UV-transmittance was 4.96% when the optimized compositions of alginate (1.05 g), AV (2.95 g), and ZnO-NPs (4.93 wt%) were used.					
35605720	8	60	theme	physical	1347:1354	arg1	properties					1389:1398	the outstanding physical, UV-shielding, and antimicrobial properties	1331:1398	the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film	1331:1440	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	2	61	theme	edible	402:407	arg1	coating					409:415	an alginate-based edible coating	384:415	an alginate-based edible coating of the best optimized UV-shielding properties	384:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	4	62	theme	successful	727:736	arg1	preparation					753:763	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components	723:876	FTIR was used to verify the successful edible coating preparation while the wide-angle X-ray diffraction (XRD) was used to identify the interactions between the film's components.					
35605720	8	63	theme	packaging	1480:1488	arg1	industries					1490:1499	food packaging industries	1475:1499	food packaging industries	1475:1499	Due to the outstanding physical, UV-shielding, and antimicrobial properties of the optimized alginate/AV/ZnO-NPs film, it could be used potentially in food packaging industries.					
35605720	1	64	theme	outstanding	158:168	arg1	characteristics					170:184	the outstanding characteristics	154:184	the outstanding characteristics of alginate	154:196	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
35605720	2	65	theme	vera	499:502	arg1	ZnO-NPs					539:545	ZnO-NPs	539:545	ZnO-NPs	539:545	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	2	65	theme	vera	499:502	arg1	nanoparticles					524:536	both Aloe vera (AV) and zinc oxide nanoparticles	489:536	both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs)	489:546	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	2	66	theme	best	424:427	arg1	properties					452:461	the best optimized UV-shielding properties	420:461	the best optimized UV-shielding properties	420:461	For this concern, Box-Behnken design (BBD) was applied to prepare an alginate-based edible coating of the best optimized UV-shielding properties upon the incorporation of both Aloe vera (AV) and zinc oxide nanoparticles (ZnO-NPs).					
35605720	1	67	theme	antimicrobial	250:262	arg1	properties					264:273	antimicrobial properties	250:273	antimicrobial properties limiting its wide usage in food packaging	250:315	Despite the outstanding characteristics of alginate, it suffers from bad UV-barrier, water barrier, and antimicrobial properties limiting its wide usage in food packaging.					
37119919	0	0	theme	gum	83:85	arg1	films					94:98	gum active films	83:98	gum active films for apple preservation	83:121	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	8	1	theme	%	1173:1173	arg1	rate					1162:1165	total polyphenol retention rate	1135:1165	total polyphenol retention rate of 91 % and 72 %, respectively	1135:1196	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	8	1	theme	%	1173:1173	arg1	C					1129:1129	vitamin C	1121:1129	vitamin C	1121:1129	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	6	2	theme	weight	925:930	arg1	loss					932:935	weight loss	925:935	weight loss	925:935	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	5	3	theme	PXG	705:707	arg1	films					709:713	PXG films	705:713	PXG films	705:713	PXG films also demonstrated inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.					
37119919	7	4	theme	loss	1016:1019	arg1	rate					1021:1024	The weight loss rate	1005:1024	The weight loss rate of PXG150	1005:1034	The weight loss rate of PXG150 was decreased from (8.58 ± 0.6)% (control) to (4.15 ± 0.19)%.					
37119919	6	5	theme	5th	996:998	arg1	day					1000:1002	the 5th day	992:1002	the 5th day	992:1002	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	10	6	theme	food	1512:1515	arg1	material					1527:1534	an excellent food packaging material	1499:1534	an excellent food packaging material	1499:1534	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	10	6	theme	food	1512:1515	arg1	it					1488:1489	it	1488:1489	it	1488:1489	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	3	7	theme	Sample	314:319	arg1	GSE					346:348	contain 100 mg/L GSE	329:348	contain 100 mg/L GSE	329:348	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	7	theme	Sample	314:319	arg1	PXG100					321:326	Sample PXG100	314:326	Sample PXG100 (contain 100 mg/L GSE)	314:349	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	0	8	from	Effects	0:6	arg1	properties					37:46	the properties	33:46	the properties of pullulan	33:58	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	7	9	theme	weight	1009:1014	arg1	rate					1021:1024	The weight loss rate	1005:1024	The weight loss rate of PXG150	1005:1034	The weight loss rate of PXG150 was decreased from (8.58 ± 0.6)% (control) to (4.15 ± 0.19)%.					
37119919	3	10	from	break	461:465	arg1	strength					409:416	tensile strength	401:416	tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%	401:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	10	from	break	461:465	arg1	elongation					447:456	the elongation	443:456	the elongation at break of (22.60 ± 0.48)%	443:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	10	from	break	461:465	arg1	16.62 ± 1.27 MPa					421:436	16.62 ± 1.27 MPa	421:436	16.62 ± 1.27 MPa	421:436	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	11	theme	%	484:484	arg1	elongation					447:456	the elongation	443:456	the elongation at break of (22.60 ± 0.48)%	443:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	11	theme	%	484:484	arg1	16.62 ± 1.27 MPa					421:436	16.62 ± 1.27 MPa	421:436	16.62 ± 1.27 MPa	421:436	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	1	12	theme	composite	211:219	arg1	extract					135:141	Grape seed extract	124:141	Grape seed extract (GSE)	124:147	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	12	theme	composite	211:219	arg1	film					221:224	composite film	211:224	composite film (PP/XG/GSE or PXG)	211:243	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	0	13	theme	active	87:92	arg1	films					94:98	gum active films	83:98	gum active films for apple preservation	83:121	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	3	14	dep	GSE	346:348	arg1	contain					329:335	contain	329:335	contain	329:335	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	9	15	dep	antibacterial	1303:1315	arg1	antioxidant					1318:1328	antioxidant	1318:1328	antioxidant	1318:1328	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	1	16	theme	seed	130:133	arg1	GSE					144:146	GSE	144:146	GSE	144:146	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	16	theme	seed	130:133	arg1	extract					135:141	Grape seed extract	124:141	Grape seed extract (GSE)	124:147	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	16	theme	seed	130:133	arg1	film					221:224	composite film	211:224	composite film (PP/XG/GSE or PXG)	211:243	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	0	17	theme	apple	104:108	arg1	preservation					110:121	apple preservation	104:121	apple preservation	104:121	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	4	18	theme	scavenging	604:613	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	18	theme	scavenging	604:613	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	18	theme	scavenging	604:613	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	19	theme	ABTS	590:593	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	19	theme	ABTS	590:593	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	19	theme	ABTS	590:593	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	9	20	theme	water	1381:1385	arg1	properties					1330:1339	the antibacterial, antioxidant properties	1299:1339	the antibacterial, antioxidant properties	1299:1339	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	20	theme	water	1381:1385	arg1	resistance					1387:1396	water resistance	1381:1396	water resistance	1381:1396	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	10	21	theme	apples	1474:1479	arg1	life					1456:1459	the shelf life	1446:1459	the shelf life of fresh-cut apples, which it will be an excellent food packaging material	1446:1534	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	4	22	theme	2,2'-azino-bis-	532:546	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	22	theme	2,2'-azino-bis-	532:546	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	22	theme	2,2'-azino-bis-	532:546	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	5	23	from	effects	744:750	arg1	coli					790:793	Escherichia coli	778:793	Escherichia coli	778:793	PXG films also demonstrated inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.					
37119919	5	23	from	effects	744:750	arg1	subtilis					809:816	Bacillus subtilis	800:816	Bacillus subtilis	800:816	PXG films also demonstrated inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.					
37119919	5	23	from	effects	744:750	arg1	aureus					770:775	Staphylococcus aureus	755:775	Staphylococcus aureus	755:775	PXG films also demonstrated inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.					
37119919	8	24	theme	%	1182:1182	arg1	rate					1162:1165	total polyphenol retention rate	1135:1165	total polyphenol retention rate of 91 % and 72 %, respectively	1135:1196	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	8	24	theme	%	1182:1182	arg1	C					1129:1129	vitamin C	1121:1129	vitamin C	1121:1129	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	10	25	theme	fresh-cut	1464:1472	arg1	apples					1474:1479	fresh-cut apples	1464:1479	fresh-cut apples	1464:1479	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	3	26	theme	100 mg/L	337:344	arg1	GSE					346:348	contain 100 mg/L GSE	329:348	contain 100 mg/L GSE	329:348	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	3	26	theme	100 mg/L	337:344	arg1	PXG100					321:326	Sample PXG100	314:326	Sample PXG100 (contain 100 mg/L GSE)	314:349	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	7	27	theme	4.15 ± 0.19	1083:1093	arg1	%					1095:1095	(4.15 ± 0.19)%	1082:1095	(4.15 ± 0.19)%	1082:1095	The weight loss rate of PXG150 was decreased from (8.58 ± 0.6)% (control) to (4.15 ± 0.19)%.					
37119919	2	28	theme	observed	250:257	arg1	morphology					269:278	The observed composite morphology	246:278	The observed composite morphology	246:278	The observed composite morphology indicated their biocompatibility.					
37119919	3	29	theme	mechanical	373:382	arg1	properties					384:393	the best mechanical properties	364:393	the best mechanical properties	364:393	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	4	30	theme	2,2-diphenyl-1-picrylhydrazyl	491:519	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	30	theme	2,2-diphenyl-1-picrylhydrazyl	491:519	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	30	theme	2,2-diphenyl-1-picrylhydrazyl	491:519	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	10	31	theme	excellent	1502:1510	arg1	material					1527:1534	an excellent food packaging material	1499:1534	an excellent food packaging material	1499:1534	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	10	31	theme	excellent	1502:1510	arg1	it					1488:1489	it	1488:1489	it	1488:1489	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	9	32	theme	PXG	1401:1403	arg1	films					1415:1419	PXG composite films	1401:1419	PXG composite films	1401:1419	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	1	33	theme	pullulan	162:169	arg1	gum					199:201	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	0	34	theme	seed	17:20	arg1	extract					22:28	grape seed extract	11:28	grape seed extract	11:28	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	8	35	theme	retention	1152:1160	arg1	rate					1162:1165	total polyphenol retention rate	1135:1165	total polyphenol retention rate of 91 % and 72 %, respectively	1135:1196	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	8	36	theme	polyphenol	1141:1150	arg1	rate					1162:1165	total polyphenol retention rate	1135:1165	total polyphenol retention rate of 91 % and 72 %, respectively	1135:1196	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	9	37	theme	composite	1405:1413	arg1	films					1415:1419	PXG composite films	1401:1419	PXG composite films	1401:1419	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	1	38	theme	polysaccharide	171:184	arg1	gum					199:201	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	0	39	theme	grape	11:15	arg1	extract					22:28	grape seed extract	11:28	grape seed extract	11:28	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	9	40	theme	UV	1363:1364	arg1	properties					1330:1339	the antibacterial, antioxidant properties	1299:1339	the antibacterial, antioxidant properties	1299:1339	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	40	theme	UV	1363:1364	arg1	protection					1366:1375	UV protection	1363:1375	UV protection	1363:1375	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	3	41	theme	16.62 ± 1.27 MPa	421:436	arg1	strength					409:416	tensile strength	401:416	tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%	401:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	6	42	theme	PXG	823:825	arg1	films					827:831	The PXG films	819:831	The PXG films	819:831	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	1	43	theme	PP	187:188	arg1	gum					199:201	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	4	44	theme	PXG150	627:632	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	44	theme	PXG150	627:632	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	44	theme	PXG150	627:632	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	3	45	theme	tensile	401:407	arg1	strength					409:416	tensile strength	401:416	tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%	401:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	0	46	theme	extract	22:28	arg1	Effects					0:6	Effects	0:6	Effects of grape seed extract on the properties of pullulan	0:58	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	6	47	theme	apples	880:885	arg1	life					862:865	the shelf life	852:865	the shelf life of fresh-cut apples	852:885	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	3	48	theme	best	368:371	arg1	properties					384:393	the best mechanical properties	364:393	the best mechanical properties	364:393	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	9	49	theme	antibacterial	1303:1315	arg1	properties					1330:1339	the antibacterial, antioxidant properties	1299:1339	the antibacterial, antioxidant properties	1299:1339	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	49	theme	antibacterial	1303:1315	arg1	strength					1353:1360	mechanical strength	1342:1360	mechanical strength	1342:1360	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	49	theme	antibacterial	1303:1315	arg1	protection					1366:1375	UV protection	1363:1375	UV protection	1363:1375	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	49	theme	antibacterial	1303:1315	arg1	resistance					1387:1396	water resistance	1381:1396	water resistance	1381:1396	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	4	50	theme	radical	596:602	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	50	theme	radical	596:602	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	50	theme	radical	596:602	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	7	51	theme	PXG150	1029:1034	arg1	rate					1021:1024	The weight loss rate	1005:1024	The weight loss rate of PXG150	1005:1034	The weight loss rate of PXG150 was decreased from (8.58 ± 0.6)% (control) to (4.15 ± 0.19)%.					
37119919	6	52	theme	fresh-cut	870:878	arg1	apples					880:885	fresh-cut apples	870:885	fresh-cut apples	870:885	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	3	53	from	strength	409:416	arg1	break					461:465	break	461:465	break	461:465	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	8	54	theme	total	1135:1139	arg1	rate					1162:1165	total polyphenol retention rate	1135:1165	total polyphenol retention rate of 91 % and 72 %, respectively	1135:1196	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	5	55	theme	inhibitory	733:742	arg1	effects					744:750	inhibitory effects	733:750	inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis	733:816	PXG films also demonstrated inhibitory effects on Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.					
37119919	10	56	theme	packaging	1517:1525	arg1	material					1527:1534	an excellent food packaging material	1499:1534	an excellent food packaging material	1499:1534	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	10	56	theme	packaging	1517:1525	arg1	it					1488:1489	it	1488:1489	it	1488:1489	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	3	57	theme	elongation	447:456	arg1	strength					409:416	tensile strength	401:416	tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%	401:484	Sample PXG100 (contain 100 mg/L GSE) demonstrated the best mechanical properties, with tensile strength of 16.62 ± 1.27 MPa, and the elongation at break of (22.60 ± 0.48)%.					
37119919	1	58	dep	film	221:224	arg1	PXG					240:242	PXG	240:242	PXG	240:242	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	58	dep	film	221:224	arg1	PP/XG/GSE					227:235	PP/XG/GSE	227:235	PP/XG/GSE	227:235	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	59	theme	Grape	124:128	arg1	GSE					144:146	GSE	144:146	GSE	144:146	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	59	theme	Grape	124:128	arg1	extract					135:141	Grape seed extract	124:141	Grape seed extract (GSE)	124:147	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	59	theme	Grape	124:128	arg1	film					221:224	composite film	211:224	composite film (PP/XG/GSE or PXG)	211:243	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	1	60	theme	/xanthan	190:197	arg1	gum					199:201	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	pullulan polysaccharide (PP)/xanthan gum (XG)	162:206	Grape seed extract (GSE) was added to pullulan polysaccharide (PP)/xanthan gum (XG) as composite film (PP/XG/GSE or PXG).					
37119919	8	61	theme	control	1239:1245	arg1	sample					1247:1252	the control sample	1235:1252	the control sample	1235:1252	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	2	62	theme	composite	259:267	arg1	morphology					269:278	The observed composite morphology	246:278	The observed composite morphology	246:278	The observed composite morphology indicated their biocompatibility.					
37119919	4	63	theme	3-ethylbenzothiazoline-6-sulphonic	548:581	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	63	theme	3-ethylbenzothiazoline-6-sulphonic	548:581	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	63	theme	3-ethylbenzothiazoline-6-sulphonic	548:581	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	0	64	theme	pullulan	51:58	arg1	properties					37:46	the properties	33:46	the properties of pullulan	33:58	Effects of grape seed extract on the properties of pullulan polysaccharide/xanthan gum active films for apple preservation.					
37119919	6	65	theme	vitamin	953:959	arg1	C					961:961	more vitamin C	948:961	more vitamin C	948:961	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	8	66	theme	vitamin	1121:1127	arg1	C					1129:1129	vitamin C	1121:1129	vitamin C	1121:1129	It was able to achieve vitamin C and total polyphenol retention rate of 91 % and 72 %, respectively, which was significantly higher that the control sample.					
37119919	6	67	theme	total	967:971	arg1	polyphenol					973:982	total polyphenol	967:982	total polyphenol	967:982	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	9	68	theme	mechanical	1342:1351	arg1	properties					1330:1339	the antibacterial, antioxidant properties	1299:1339	the antibacterial, antioxidant properties	1299:1339	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	9	68	theme	mechanical	1342:1351	arg1	strength					1353:1360	mechanical strength	1342:1360	mechanical strength	1342:1360	Therefore, GSE had contributed in enhancing the antibacterial, antioxidant properties, mechanical strength, UV protection and water resistance in PXG composite films.					
37119919	10	69	theme	shelf	1450:1454	arg1	life					1456:1459	the shelf life	1446:1459	the shelf life of fresh-cut apples, which it will be an excellent food packaging material	1446:1534	This effectively extend the shelf life of fresh-cut apples, which it will be an excellent food packaging material.					
37119919	6	70	theme	shelf	856:860	arg1	life					862:865	the shelf life	852:865	the shelf life of fresh-cut apples	852:885	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
37119919	4	71	theme	acid	583:586	arg1	highest					643:649	highest	643:649	highest	643:649	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	71	theme	acid	583:586	arg1	activity					615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	activity	615:622	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	4	71	theme	acid	583:586	arg1	DPPH					522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity	487:622	DPPH	522:525	The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity of PXG150 were the highest at (81.52 ± 1.57)% and (90.85 ± 1.54)%, respectively.					
37119919	6	72	theme	loss	932:935	arg1	rate					917:920	the rate	913:920	the rate of weight loss	913:935	The PXG films could also prolong the shelf life of fresh-cut apples because it could decrease the rate of weight loss and retain more vitamin C and total polyphenol even on the 5th day.					
36441906	12	0	theme	artificial	2169:2178	arg1	keratoplasty					2180:2191	artificial keratoplasty	2169:2191	artificial keratoplasty	2169:2191	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	7	1	theme	excellent	1223:1231	arg1	transmittance					1239:1251	excellent light transmittance	1223:1251	excellent light transmittance (up to 95.96%)	1223:1266	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	7	1	theme	excellent	1223:1231	arg1	%					1265:1265	up to 95.96%	1254:1265	up to 95.96%	1254:1265	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	11	2	theme	current	1990:1996	arg1	industry					2016:2023	the current cosmetic medicine industry	1986:2023	the current cosmetic medicine industry owing to its long-term safety records for over 15 years	1986:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	10	3	theme	corneal	1799:1805	arg1	cells					1815:1819	The rabbit corneal stromal cells	1788:1819	The rabbit corneal stromal cells cultured in vitro	1788:1837	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	11	4	theme	medicine	2007:2014	arg1	industry					2016:2023	the current cosmetic medicine industry	1986:2023	the current cosmetic medicine industry owing to its long-term safety records for over 15 years	1986:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	11	5	theme	safety	2048:2053	arg1	records					2055:2061	its long-term safety records	2034:2061	its long-term safety records for over 15 years	2034:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	11	6	theme	cosmetic	1998:2005	arg1	industry					2016:2023	the current cosmetic medicine industry	1986:2023	the current cosmetic medicine industry owing to its long-term safety records for over 15 years	1986:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	4	7	theme	mechanical	694:703	arg1	properties					705:714	mechanical properties	694:714	mechanical properties	694:714	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	2	8	theme	new	311:313	arg1	cornea					326:331	a new artificial cornea	309:331	a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties	309:446	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	5	9	theme	diglycidyl	884:893	arg1	BDDE					902:905	BDDE	902:905	BDDE	902:905	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	9	theme	diglycidyl	884:893	arg1	ether					895:899	1,4-butanediol diglycidyl ether	869:899	1,4-butanediol diglycidyl ether (BDDE)	869:906	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	9	theme	diglycidyl	884:893	arg1	agent					938:942	the chemical cross-linking agent	911:942	the chemical cross-linking agent	911:942	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	11	10	theme	HA	1971:1972	arg1	products					1974:1981	most HA products	1966:1981	most HA products	1966:1981	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	4	11	theme	artificial	648:657	arg1	keratoplasty					659:670	artificial keratoplasty	648:670	artificial keratoplasty	648:670	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	3	12	theme	horizontal	579:588	arg1	reactor					602:608	a horizontal rotary drum reactor	577:608	a horizontal rotary drum reactor	577:608	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	5	13	theme	BNC/HA	834:839	arg1	membrane					851:858	the BNC/HA composite membrane	830:858	the BNC/HA composite membrane	830:858	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	9	14	theme	three-dimensional	1611:1627	arg1	scaffold					1637:1644	the three-dimensional network scaffold	1607:1644	the three-dimensional network scaffold of BNC	1607:1651	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	4	15	theme	membrane	731:738	arg1	transparency					677:688	transparency	677:688	transparency	677:688	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	4	15	theme	membrane	731:738	arg1	properties					705:714	mechanical properties	694:714	mechanical properties	694:714	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	8	16	theme	composite	1273:1281	arg1	membrane					1283:1290	The composite membrane	1269:1290	The composite membrane	1269:1290	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	5	17	theme	cross-linking	924:936	arg1	agent					938:942	the chemical cross-linking agent	911:942	the chemical cross-linking agent	911:942	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	17	theme	cross-linking	924:936	arg1	ether					895:899	1,4-butanediol diglycidyl ether	869:899	1,4-butanediol diglycidyl ether (BDDE)	869:906	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	6	18	theme	moisture	1026:1033	arg1	ability					1045:1051	moisture retention ability	1026:1051	moisture retention ability	1026:1051	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	9	19	theme	BNC	1649:1651	arg1	characteristics					1683:1697	the high water absorption characteristics	1657:1697	the high water absorption characteristics of HA	1657:1703	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	9	19	theme	BNC	1649:1651	arg1	scaffold					1637:1644	the three-dimensional network scaffold	1607:1644	the three-dimensional network scaffold of BNC	1607:1651	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	10	20	contain	had	1884:1886	arg2	cytocompatibility					1898:1914	excellent cytocompatibility	1888:1914	excellent cytocompatibility	1888:1914	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	10	20	contain	had	1884:1886	arg1	cornea					1866:1871	the artificial cornea substitute	1851:1882	the artificial cornea substitute	1851:1882	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	0	21	theme	Artificial	80:89	arg1	Cornea					91:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	8	22	theme	burst	1449:1453	arg1	kPa					1478:1480	about 130 kPa	1468:1480	about 130 kPa	1468:1480	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	22	theme	burst	1449:1453	arg1	pressure					1455:1462	the maximum burst pressure	1437:1462	the maximum burst pressure	1437:1462	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	11	23	theme	used	1945:1948	arg1	BDDE					1917:1920	BDDE	1917:1920	BDDE	1917:1920	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	11	23	theme	used	1945:1948	arg1	cross-linker					1950:1961	the most frequently used cross-linker	1925:1961	the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years	1925:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	4	24	theme	new	723:725	arg1	membrane					731:738	the new BNC membrane	719:738	the new BNC membrane	719:738	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	1	25	theme	corneal	190:196	arg1	transplantation					198:212	donor corneal transplantation	184:212	donor corneal transplantation	184:212	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	9	26	theme	water	1666:1670	arg1	characteristics					1683:1697	the high water absorption characteristics	1657:1697	the high water absorption characteristics of HA	1657:1703	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	12	27	theme	surface	2203:2209	arg1	repair					2211:2216	ocular surface repair	2196:2216	ocular surface repair	2196:2216	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	6	28	theme	mechanical	988:997	arg1	properties					999:1008	mechanical properties	988:1008	mechanical properties	988:1008	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	12	29	theme	great	2150:2154	arg1	potential					2156:2164	great potential	2150:2164	great potential	2150:2164	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	3	30	theme	new	451:453	arg1	membrane					485:492	A new bacterial nanocellulose (BNC) membrane	449:492	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission	449:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	0	31	theme	Transplantation	125:139	arg1	Application					102:112	Application	102:112	Application of Corneal Transplantation	102:139	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	6	32	theme	composite	1083:1091	arg1	membranes					1093:1101	the composite membranes	1079:1101	the composite membranes	1079:1101	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	9	33	theme	HA	1702:1703	arg1	characteristics					1683:1697	the high water absorption characteristics	1657:1697	the high water absorption characteristics of HA	1657:1703	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	9	33	theme	HA	1702:1703	arg1	scaffold					1637:1644	the three-dimensional network scaffold	1607:1644	the three-dimensional network scaffold of BNC	1607:1651	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	1	34	theme	corneal	160:166	arg1	damage					168:173	corneal damage	160:173	corneal damage	160:173	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	0	35	theme	Cornea	91:96	arg1	Evaluation					16:25	Evaluation	16:25	Evaluation	16:25	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	0	35	theme	Cornea	91:96	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	12	36	theme	composite	2104:2112	arg1	hydrogel					2114:2121	the BNC/HA composite hydrogel	2093:2121	the BNC/HA composite hydrogel cross-linked with BDDE	2093:2144	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	2	37	theme	suture	395:400	arg1	resistance					402:411	suture resistance	395:411	suture resistance	395:411	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	3	38	theme	BNC	480:482	arg1	membrane					485:492	A new bacterial nanocellulose (BNC) membrane	449:492	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission	449:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	7	39	theme	ether	1166:1170	arg1	bond					1172:1175	the ether bond	1162:1175	the ether bond	1162:1175	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	3	40	theme	nanocellulose	465:477	arg1	membrane					485:492	A new bacterial nanocellulose (BNC) membrane	449:492	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission	449:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	2	41	theme	great	418:422	arg1	properties					437:446	great moisturizing properties	418:446	great moisturizing properties	418:446	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	0	42	theme	Bacterial	30:38	arg1	Cornea					91:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	9	43	theme	high	1732:1735	arg1	content					1743:1749	high water content	1732:1749	high water content	1732:1749	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	8	44	theme	normal	1507:1512	arg1	IOP					1514:1516	the normal IOP	1503:1516	the normal IOP	1503:1516	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	45	theme	normal	1386:1391	arg1	pressure					1405:1412	the human normal intraocular pressure	1376:1412	the human normal intraocular pressure (IOP) (1.33-2.80 kPa)	1376:1434	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	45	theme	normal	1386:1391	arg1	kPa					1431:1433	1.33-2.80 kPa	1421:1433	1.33-2.80 kPa	1421:1433	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	45	theme	normal	1386:1391	arg1	IOP					1415:1417	IOP	1415:1417	IOP	1415:1417	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	3	46	theme	anisotropic	499:509	arg1	properties					522:531	anisotropic mechanical properties	499:531	anisotropic mechanical properties	499:531	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	0	47	theme	Acid	65:68	arg1	Cornea					91:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	10	48	theme	excellent	1888:1896	arg1	cytocompatibility					1898:1914	excellent cytocompatibility	1888:1914	excellent cytocompatibility	1888:1914	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	9	49	theme	high	1755:1758	arg1	ability					1779:1785	high moisture retention ability	1755:1785	high moisture retention ability	1755:1785	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	3	50	theme	high	537:540	arg1	transmission					548:559	high light transmission	537:559	high light transmission	537:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	8	51	theme	amniotic	1571:1578	arg1	membrane					1580:1587	the human amniotic membrane	1561:1587	the human amniotic membrane (0.1 N)	1561:1595	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	51	theme	amniotic	1571:1578	arg1	N					1594:1594	0.1 N	1590:1594	0.1 N	1590:1594	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	1	52	theme	corneas	256:262	arg1	worldwide					264:272	donor corneas worldwide	250:272	donor corneas worldwide	250:272	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	9	53	theme	retention	1769:1777	arg1	ability					1779:1785	high moisture retention ability	1755:1785	high moisture retention ability	1755:1785	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	4	54	theme	potential	625:633	arg1	material					635:642	a potential material	623:642	a potential material for artificial keratoplasty	623:670	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	10	55	theme	stromal	1807:1813	arg1	cells					1815:1819	The rabbit corneal stromal cells	1788:1819	The rabbit corneal stromal cells cultured in vitro	1788:1837	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	2	56	theme	excellent	362:370	arg1	properties					380:389	excellent optical properties	362:389	excellent optical properties	362:389	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	7	57	theme	light	1233:1237	arg1	transmittance					1239:1251	excellent light transmittance	1223:1251	excellent light transmittance (up to 95.96%)	1223:1266	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	7	57	theme	light	1233:1237	arg1	%					1265:1265	up to 95.96%	1254:1265	up to 95.96%	1254:1265	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	10	58	theme	rabbit	1792:1797	arg1	cells					1815:1819	The rabbit corneal stromal cells	1788:1819	The rabbit corneal stromal cells cultured in vitro	1788:1837	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	2	59	theme	artificial	315:324	arg1	cornea					326:331	a new artificial cornea	309:331	a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties	309:446	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	8	60	theme	mechanical	1309:1318	arg1	properties					1320:1329	excellent mechanical properties	1299:1329	excellent mechanical properties	1299:1329	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	3	61	with	membrane	485:492	arg1	transmission					548:559	high light transmission	537:559	high light transmission	537:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	3	61	with	membrane	485:492	arg1	properties					522:531	anisotropic mechanical properties	499:531	anisotropic mechanical properties	499:531	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	7	62	theme	BNC	1147:1149	arg1	network					1151:1157	the BNC network	1143:1157	the BNC network by the ether bond	1143:1175	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	3	63	theme	rotary	590:595	arg1	reactor					602:608	a horizontal rotary drum reactor	577:608	a horizontal rotary drum reactor	577:608	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	5	64	theme	1,4-butanediol	869:882	arg1	BDDE					902:905	BDDE	902:905	BDDE	902:905	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	64	theme	1,4-butanediol	869:882	arg1	ether					895:899	1,4-butanediol diglycidyl ether	869:899	1,4-butanediol diglycidyl ether (BDDE)	869:906	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	64	theme	1,4-butanediol	869:882	arg1	agent					938:942	the chemical cross-linking agent	911:942	the chemical cross-linking agent	911:942	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	11	65	theme	long-term	2038:2046	arg1	records					2055:2061	its long-term safety records	2034:2061	its long-term safety records for over 15 years	2034:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	10	66	theme	artificial	1855:1864	arg1	cornea					1866:1871	the artificial cornea substitute	1851:1882	the artificial cornea substitute	1851:1882	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	3	67	theme	drum	597:600	arg1	reactor					602:608	a horizontal rotary drum reactor	577:608	a horizontal rotary drum reactor	577:608	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	6	68	theme	light	967:971	arg1	transmittance					973:985	light transmittance	967:985	light transmittance	967:985	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	2	69	theme	good	338:341	arg1	cytocompatibility					343:359	good cytocompatibility	338:359	good cytocompatibility	338:359	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	5	70	theme	composite	841:849	arg1	membrane					851:858	the BNC/HA composite membrane	830:858	the BNC/HA composite membrane	830:858	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	11	71	theme	most	1966:1969	arg1	products					1974:1981	most HA products	1966:1981	most HA products	1966:1981	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	7	72	theme	composite	1186:1194	arg1	membrane					1196:1203	the composite membrane	1182:1203	the composite membrane	1182:1203	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	9	73	theme	network	1629:1635	arg1	scaffold					1637:1644	the three-dimensional network scaffold	1607:1644	the three-dimensional network scaffold of BNC	1607:1651	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	4	74	theme	BNC	727:729	arg1	membrane					731:738	the new BNC membrane	719:738	the new BNC membrane	719:738	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	5	75	theme	chemical	915:922	arg1	agent					938:942	the chemical cross-linking agent	911:942	the chemical cross-linking agent	911:942	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	75	theme	chemical	915:922	arg1	ether					895:899	1,4-butanediol diglycidyl ether	869:899	1,4-butanediol diglycidyl ether (BDDE)	869:906	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	6	76	theme	retention	1035:1043	arg1	ability					1045:1051	moisture retention ability	1026:1051	moisture retention ability	1026:1051	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	8	77	theme	maximum	1441:1447	arg1	kPa					1478:1480	about 130 kPa	1468:1480	about 130 kPa	1468:1480	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	77	theme	maximum	1441:1447	arg1	pressure					1455:1462	the maximum burst pressure	1437:1462	the maximum burst pressure	1437:1462	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	5	78	theme	hyaluronic	769:778	arg1	acid					780:783	hyaluronic acid	769:783	hyaluronic acid (HA)	769:788	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	5	78	theme	hyaluronic	769:778	arg1	HA					786:787	HA	786:787	HA	786:787	Thus, hyaluronic acid (HA) was introduced in the BNC to synthesize the BNC/HA composite membrane by using 1,4-butanediol diglycidyl ether (BDDE) as the chemical cross-linking agent.					
36441906	9	79	contain	had	1728:1730	arg2	content					1743:1749	high water content	1732:1749	high water content	1732:1749	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	9	79	contain	had	1728:1730	arg2	ability					1779:1785	high moisture retention ability	1755:1785	high moisture retention ability	1755:1785	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	9	79	contain	had	1728:1730	arg1	cornea					1721:1726	the artificial cornea	1706:1726	the artificial cornea	1706:1726	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	12	80	theme	ocular	2196:2201	arg1	repair					2211:2216	ocular surface repair	2196:2216	ocular surface repair	2196:2216	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	1	81	theme	donor	184:188	arg1	transplantation					198:212	donor corneal transplantation	184:212	donor corneal transplantation	184:212	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	6	82	theme	water	1011:1015	arg1	content					1017:1023	water content	1011:1023	water content	1011:1023	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	9	83	theme	high	1661:1664	arg1	characteristics					1683:1697	the high water absorption characteristics	1657:1697	the high water absorption characteristics of HA	1657:1703	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	7	84	from	network	1151:1157	arg1	fixed					1134:1138	fixed	1134:1138	fixed	1134:1138	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	8	85	theme	excellent	1299:1307	arg1	properties					1320:1329	excellent mechanical properties	1299:1329	excellent mechanical properties	1299:1329	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	0	86	theme	Corneal	117:123	arg1	Transplantation					125:139	Corneal Transplantation	117:139	Corneal Transplantation	117:139	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	9	87	theme	absorption	1672:1681	arg1	characteristics					1683:1697	the high water absorption characteristics	1657:1697	the high water absorption characteristics of HA	1657:1703	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	12	88	contain	has	2146:2148	arg1	hydrogel					2114:2121	the BNC/HA composite hydrogel	2093:2121	the BNC/HA composite hydrogel cross-linked with BDDE	2093:2144	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	12	88	contain	has	2146:2148	arg2	potential					2156:2164	great potential	2150:2164	great potential	2150:2164	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	7	89	dep	95.96	1260:1264	arg1	to					1257:1258	to	1257:1258	to	1257:1258	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	6	90	theme	membranes	1093:1101	arg1	ability					1045:1051	moisture retention ability	1026:1051	moisture retention ability	1026:1051	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	6	90	theme	membranes	1093:1101	arg1	cytocompatibility					1058:1074	cytocompatibility	1058:1074	cytocompatibility	1058:1074	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	6	90	theme	membranes	1093:1101	arg1	transmittance					973:985	light transmittance	967:985	light transmittance	967:985	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	6	90	theme	membranes	1093:1101	arg1	content					1017:1023	water content	1011:1023	water content	1011:1023	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	6	90	theme	membranes	1093:1101	arg1	micro-morphology					949:964	The micro-morphology	945:964	The micro-morphology	945:964	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	6	90	theme	membranes	1093:1101	arg1	properties					999:1008	mechanical properties	988:1008	mechanical properties	988:1008	The micro-morphology, light transmittance, mechanical properties, water content, moisture retention ability, and cytocompatibility of the composite membranes were further evaluated.					
36441906	10	91	dep	cornea	1866:1871	arg1	substitute					1873:1882	substitute	1873:1882	substitute	1873:1882	The rabbit corneal stromal cells cultured in vitro showed that the artificial cornea substitute had excellent cytocompatibility.					
36441906	1	92	theme	serious	230:236	arg1	scarcity					238:245	a serious scarcity	228:245	a serious scarcity of donor corneas worldwide	228:272	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	3	93	theme	bacterial	455:463	arg1	membrane					485:492	A new bacterial nanocellulose (BNC) membrane	449:492	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission	449:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	12	94	theme	BNC/HA	2097:2102	arg1	hydrogel					2114:2121	the BNC/HA composite hydrogel	2093:2121	the BNC/HA composite hydrogel cross-linked with BDDE	2093:2144	Therefore, the BNC/HA composite hydrogel cross-linked with BDDE has great potential in artificial keratoplasty or ocular surface repair.					
36441906	9	95	theme	artificial	1710:1719	arg1	cornea					1721:1726	the artificial cornea	1706:1726	the artificial cornea	1706:1726	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	8	96	theme	tensile	1350:1356	arg1	strength					1358:1365	its tensile strength	1346:1365	its tensile strength	1346:1365	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	2	97	theme	moisturizing	424:435	arg1	properties					437:446	great moisturizing properties	418:446	great moisturizing properties	418:446	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	0	98	theme	Nanocellulose/Hyaluronic	40:63	arg1	Cornea					91:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	2	99	with	cornea	326:331	arg1	resistance					402:411	suture resistance	395:411	suture resistance	395:411	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	2	99	with	cornea	326:331	arg1	properties					437:446	great moisturizing properties	418:446	great moisturizing properties	418:446	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	2	99	with	cornea	326:331	arg1	cytocompatibility					343:359	good cytocompatibility	338:359	good cytocompatibility	338:359	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	2	99	with	cornea	326:331	arg1	properties					380:389	excellent optical properties	362:389	excellent optical properties	362:389	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	11	100	from	cross-linker	1950:1961	arg1	products					1974:1981	most HA products	1966:1981	most HA products	1966:1981	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	11	100	from	cross-linker	1950:1961	arg1	industry					2016:2023	the current cosmetic medicine industry	1986:2023	the current cosmetic medicine industry owing to its long-term safety records for over 15 years	1986:2079	BDDE is the most frequently used cross-linker in most HA products in the current cosmetic medicine industry owing to its long-term safety records for over 15 years.					
36441906	8	101	theme	IOP	1514:1516	arg1	kPa					1478:1480	about 130 kPa	1468:1480	about 130 kPa	1468:1480	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	101	theme	IOP	1514:1516	arg1	times					1489:1493	46-97 times	1483:1493	46-97 times that of the normal IOP	1483:1516	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	0	102	theme	Composite	70:78	arg1	Cornea					91:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea	30:96	Preparation and Evaluation of Bacterial Nanocellulose/Hyaluronic Acid Composite Artificial Cornea for Application of Corneal Transplantation.					
36441906	9	103	theme	water	1737:1741	arg1	content					1743:1749	high water content	1732:1749	high water content	1732:1749	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	7	104	from	fixed	1134:1138	arg1	network					1151:1157	the BNC network	1143:1157	the BNC network by the ether bond	1143:1175	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	8	105	theme	human	1380:1384	arg1	pressure					1405:1412	the human normal intraocular pressure	1376:1412	the human normal intraocular pressure (IOP) (1.33-2.80 kPa)	1376:1434	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	105	theme	human	1380:1384	arg1	kPa					1431:1433	1.33-2.80 kPa	1421:1433	1.33-2.80 kPa	1421:1433	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	105	theme	human	1380:1384	arg1	IOP					1415:1417	IOP	1415:1417	IOP	1415:1417	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	3	106	theme	mechanical	511:520	arg1	properties					522:531	anisotropic mechanical properties	499:531	anisotropic mechanical properties	499:531	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	8	107	theme	human	1565:1569	arg1	membrane					1580:1587	the human amniotic membrane	1561:1587	the human amniotic membrane (0.1 N)	1561:1595	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	107	theme	human	1565:1569	arg1	N					1594:1594	0.1 N	1590:1594	0.1 N	1590:1594	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	108	theme	suture	1527:1532	arg1	force					1534:1538	its suture force	1523:1538	its suture force	1523:1538	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	109	theme	intraocular	1393:1403	arg1	pressure					1405:1412	the human normal intraocular pressure	1376:1412	the human normal intraocular pressure (IOP) (1.33-2.80 kPa)	1376:1434	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	109	theme	intraocular	1393:1403	arg1	kPa					1431:1433	1.33-2.80 kPa	1421:1433	1.33-2.80 kPa	1421:1433	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	8	109	theme	intraocular	1393:1403	arg1	IOP					1415:1417	IOP	1415:1417	IOP	1415:1417	The composite membrane showed excellent mechanical properties, for instance, its tensile strength exceeded the human normal intraocular pressure (IOP) (1.33-2.80 kPa), the maximum burst pressure was about 130 kPa, 46-97 times that of the normal IOP, and its suture force was close to that of the human amniotic membrane (0.1 N).					
36441906	2	110	theme	optical	372:378	arg1	properties					380:389	excellent optical properties	362:389	excellent optical properties	362:389	In this study, we aimed to design a new artificial cornea with good cytocompatibility, excellent optical properties and suture resistance, and great moisturizing properties.					
36441906	1	111	theme	donor	250:254	arg1	worldwide					264:272	donor corneas worldwide	250:272	donor corneas worldwide	250:272	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36441906	4	112	dep	transparency	677:688	arg1	the					673:675	the	673:675	the	673:675	However, as a potential material for artificial keratoplasty, the transparency and mechanical properties of the new BNC membrane were not satisfactory.					
36441906	9	113	theme	moisture	1760:1767	arg1	ability					1779:1785	high moisture retention ability	1755:1785	high moisture retention ability	1755:1785	Based on the three-dimensional network scaffold of BNC and the high water absorption characteristics of HA, the artificial cornea had high water content and high moisture retention ability.					
36441906	7	114	contain	have	1218:1221	arg2	%					1265:1265	up to 95.96%	1254:1265	up to 95.96%	1254:1265	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	7	114	contain	have	1218:1221	arg1	membrane					1196:1203	the composite membrane	1182:1203	the composite membrane	1182:1203	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	7	114	contain	have	1218:1221	arg2	transmittance					1239:1251	excellent light transmittance	1223:1251	excellent light transmittance (up to 95.96%)	1223:1266	HA was fixed in the BNC network by the ether bond, and the composite membrane was found to have excellent light transmittance (up to 95.96%).					
36441906	3	115	theme	light	542:546	arg1	transmission					548:559	high light transmission	537:559	high light transmission	537:559	A new bacterial nanocellulose (BNC) membrane with anisotropic mechanical properties and high light transmission was produced in a horizontal rotary drum reactor.					
36441906	1	116	theme	worldwide	264:272	arg1	scarcity					238:245	a serious scarcity	228:245	a serious scarcity of donor corneas worldwide	228:272	The treatment for corneal damage requires donor corneal transplantation, but there is a serious scarcity of donor corneas worldwide.					
36924868	6	0	theme	adsorption	953:962	arg1	capacity					964:971	an adsorption capacity	950:971	an adsorption capacity of about 26 mg/g	950:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	7	1	theme	blue	1024:1027	arg1	methylene					1014:1022	methylene blue	1014:1027	methylene blue	1014:1027	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	2	2	theme	ideal	357:361	arg1	adsorbents					363:372	the ideal adsorbents	353:372	the ideal adsorbents	353:372	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	1	3	theme	aqueous	257:263	arg1	solutions					265:273	aqueous solutions	257:273	aqueous solutions	257:273	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	0	4	theme	alginate-based	65:78	arg1	hydrogels					80:88	alginate-based hydrogels	65:88	alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid	65:138	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	3	5	from	separation	402:411	arg1	processes					427:435	adsorption processes	416:435	adsorption processes	416:435	Due to their low separation in adsorption processes, embedding into alginate and obtaining composite beads are suggested as a suitable strategy.					
36924868	9	6	theme	hydrogen	1332:1339	arg1	bonding					1341:1347	hydrogen bonding	1332:1347	hydrogen bonding	1332:1347	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	4	7	theme	-sawdust/UiO-66-NH2	571:589	arg1	beads					600:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	5	8	theme	methyl	745:750	arg1	orange					752:757	methyl orange	745:757	methyl orange	745:757	This sorbent indicated an excellent selectivity for removing methylene blue versus methyl orange in a binary system.					
36924868	9	9	theme	blue	1257:1260	arg1	methylene					1247:1255	methylene blue	1247:1260	methylene blue	1247:1260	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	2	10	theme	Zr-based	292:299	arg1	framework					315:323	Zr-based metal-organic framework	292:323	Zr-based metal-organic framework (UiO-66-NH2)	292:336	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	2	10	theme	Zr-based	292:299	arg1	UiO-66-NH2					326:335	UiO-66-NH2	326:335	UiO-66-NH2	326:335	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	10	11	theme	Ca-alginate/CA-sawdust/UiO-66-NH2	1433:1465	arg1	beads					1476:1480	Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1433:1480	Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1433:1480	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	10	12	theme	dye	1522:1524	arg1	removal					1526:1532	cationic dye removal	1513:1532	cationic dye removal	1513:1532	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	6	13	theme	blue	823:826	arg1	amount = 80 mg					797:810	adsorbent amount = 80 mg	787:810	adsorbent amount = 80 mg	787:810	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	13	theme	blue	823:826	arg1	time = 420 min					865:878	contact time = 420 min	857:878	contact time = 420 min	857:878	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	13	theme	blue	823:826	arg1	pH = 6					779:784	pH = 6	779:784	pH = 6	779:784	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	13	theme	blue	823:826	arg1	concentration = 10 mg/L					828:850	methylene blue concentration = 10 mg/L	813:850	methylene blue concentration = 10 mg/L	813:850	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	13	theme	blue	823:826	arg1	parameters					905:914	optimal parameters	897:914	optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g	897:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	14	with	adsorption	934:943	arg1	capacity					964:971	an adsorption capacity	950:971	an adsorption capacity of about 26 mg/g	950:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	0	15	theme	acid-sawdust/UiO-66-NH2	109:131	arg1	hybrid					133:138	citric acid-sawdust/UiO-66-NH2 hybrid	102:138	citric acid-sawdust/UiO-66-NH2 hybrid	102:138	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	6	16	theme	blue	929:932	arg1	adsorption					934:943	methylene blue adsorption	919:943	methylene blue adsorption with an adsorption capacity of about 26 mg/g	919:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	8	17	theme	regeneration	1116:1127	arg1	test					1129:1132	The regeneration test	1112:1132	The regeneration test	1112:1132	The regeneration test demonstrated methylene blue removal efficiency higher than about 89 % after 9 cycles.					
36924868	7	18	theme	removal	995:1001	arg1	process					1003:1009	The removal process	991:1009	The removal process of methylene blue	991:1027	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	1	19	theme	sustainable	183:193	arg1	method					209:214	a sustainable and effective method	181:214	a sustainable and effective method for removing contaminants like dyes from aqueous solutions	181:273	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	0	20	theme	citric	102:107	arg1	hybrid					133:138	citric acid-sawdust/UiO-66-NH2 hybrid	102:138	citric acid-sawdust/UiO-66-NH2 hybrid	102:138	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	9	21	theme	aromatic	1378:1385	arg1	rings					1387:1391	the aromatic rings	1374:1391	the aromatic rings	1374:1391	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	4	22	theme	hydrogel	591:598	arg1	beads					600:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	10	23	theme	cationic	1513:1520	arg1	removal					1526:1532	cationic dye removal	1513:1532	cationic dye removal	1513:1532	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	9	24	theme	rings	1387:1391	arg1	interactions					1358:1369	π-π interactions	1354:1369	π-π interactions	1354:1369	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	9	24	theme	rings	1387:1391	arg1	bonding					1341:1347	hydrogen bonding	1332:1347	hydrogen bonding	1332:1347	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	8	25	theme	higher	1181:1186	arg1	efficiency					1170:1179	methylene blue removal efficiency	1147:1179	methylene blue removal efficiency higher than about 89 % after 9 cycles	1147:1217	The regeneration test demonstrated methylene blue removal efficiency higher than about 89 % after 9 cycles.					
36924868	3	26	theme	adsorption	416:425	arg1	processes					427:435	adsorption processes	416:435	adsorption processes	416:435	Due to their low separation in adsorption processes, embedding into alginate and obtaining composite beads are suggested as a suitable strategy.					
36924868	0	27	theme	Comparative	0:10	arg1	study					12:16	Comparative study	0:16	Comparative study for removal of cationic and anionic dyes	0:57	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	5	28	theme	blue	733:736	arg1	methylene					723:731	methylene blue	723:736	methylene blue	723:736	This sorbent indicated an excellent selectivity for removing methylene blue versus methyl orange in a binary system.					
36924868	6	29	theme	adsorbent	787:795	arg1	amount = 80 mg					797:810	adsorbent amount = 80 mg	787:810	adsorbent amount = 80 mg	787:810	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	29	theme	adsorbent	787:795	arg1	time = 420 min					865:878	contact time = 420 min	857:878	contact time = 420 min	857:878	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	29	theme	adsorbent	787:795	arg1	pH = 6					779:784	pH = 6	779:784	pH = 6	779:784	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	29	theme	adsorbent	787:795	arg1	concentration = 10 mg/L					828:850	methylene blue concentration = 10 mg/L	813:850	methylene blue concentration = 10 mg/L	813:850	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	29	theme	adsorbent	787:795	arg1	parameters					905:914	optimal parameters	897:914	optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g	897:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	10	30	theme	beads	1476:1480	arg1	potential					1420:1428	the potential	1416:1428	the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1416:1480	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	10	30	theme	beads	1476:1480	arg1	bio-sorbent					1497:1507	a selective bio-sorbent	1485:1507	a selective bio-sorbent for cationic dye removal	1485:1532	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	6	31	from	parameters	905:914	arg1	adsorption					934:943	methylene blue adsorption	919:943	methylene blue adsorption with an adsorption capacity of about 26 mg/g	919:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	4	32	theme	acid	562:565	arg1	beads					600:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	8	33	theme	blue	1157:1160	arg1	efficiency					1170:1179	methylene blue removal efficiency	1147:1179	methylene blue removal efficiency higher than about 89 % after 9 cycles	1147:1217	The regeneration test demonstrated methylene blue removal efficiency higher than about 89 % after 9 cycles.					
36924868	10	34	theme	hydrogel	1467:1474	arg1	beads					1476:1480	Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1433:1480	Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1433:1480	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	1	35	theme	effective	199:207	arg1	method					209:214	a sustainable and effective method	181:214	a sustainable and effective method for removing contaminants like dyes from aqueous solutions	181:273	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	7	36	theme	linear	1038:1043	arg1	isotherm					1056:1063	linear Freundlich isotherm	1038:1063	linear Freundlich isotherm	1038:1063	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	9	37	theme	adsorbent	1287:1295	arg1	surface					1297:1303	the adsorbent surface	1283:1303	the adsorbent surface	1283:1303	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	2	38	theme	metal-organic	301:313	arg1	framework					315:323	Zr-based metal-organic framework	292:323	Zr-based metal-organic framework (UiO-66-NH2)	292:336	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	2	38	theme	metal-organic	301:313	arg1	UiO-66-NH2					326:335	UiO-66-NH2	326:335	UiO-66-NH2	326:335	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	0	39	theme	cationic	33:40	arg1	dyes					54:57	cationic and anionic dyes	33:57	cationic and anionic dyes	33:57	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	4	40	used	used	611:614	arg2	beads					600:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	6	41	theme	optimal	897:903	arg1	amount = 80 mg					797:810	adsorbent amount = 80 mg	787:810	adsorbent amount = 80 mg	787:810	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	41	theme	optimal	897:903	arg1	time = 420 min					865:878	contact time = 420 min	857:878	contact time = 420 min	857:878	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	41	theme	optimal	897:903	arg1	pH = 6					779:784	pH = 6	779:784	pH = 6	779:784	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	41	theme	optimal	897:903	arg1	concentration = 10 mg/L					828:850	methylene blue concentration = 10 mg/L	813:850	methylene blue concentration = 10 mg/L	813:850	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	41	theme	optimal	897:903	arg1	parameters					905:914	optimal parameters	897:914	optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g	897:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	10	42	theme	selective	1487:1495	arg1	bio-sorbent					1497:1507	a selective bio-sorbent	1485:1507	a selective bio-sorbent for cationic dye removal	1485:1532	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	10	42	theme	selective	1487:1495	arg1	potential					1420:1428	the potential	1416:1428	the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads	1416:1480	These results confirm the potential of Ca-alginate/CA-sawdust/UiO-66-NH2 hydrogel beads as a selective bio-sorbent for cationic dye removal.					
36924868	1	43	from	solutions	265:273	arg1	dyes					247:250	dyes	247:250	dyes from aqueous solutions	247:273	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	9	44	attach	attached	1271:1278	arg1	surface					1297:1303	the adsorbent surface	1283:1303	the adsorbent surface	1283:1303	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	9	44	attach	attached	1271:1278	arg2	methylene					1247:1255	methylene blue	1247:1260	methylene blue	1247:1260	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	4	45	theme	dyes	648:651	arg1	removal					653:659	cationic and anionic dyes removal	627:659	cationic and anionic dyes removal	627:659	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	0	46	theme	anionic	46:52	arg1	dyes					54:57	cationic and anionic dyes	33:57	cationic and anionic dyes	33:57	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	6	47	theme	26 mg/g	982:988	arg1	capacity					964:971	an adsorption capacity	950:971	an adsorption capacity of about 26 mg/g	950:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	7	48	theme	nonlinear	1069:1077	arg1	models					1104:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	3	49	theme	low	398:400	arg1	separation					402:411	their low separation	392:411	their low separation in adsorption processes	392:435	Due to their low separation in adsorption processes, embedding into alginate and obtaining composite beads are suggested as a suitable strategy.					
36924868	4	50	theme	Ca-alginate/citric	543:560	arg1	CA					568:569	CA	568:569	CA	568:569	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	4	50	theme	Ca-alginate/citric	543:560	arg1	acid					562:565	Ca-alginate/citric acid	543:565	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	5	51	theme	excellent	688:696	arg1	selectivity					698:708	an excellent selectivity	685:708	an excellent selectivity for removing methylene blue versus methyl orange in a binary system	685:776	This sorbent indicated an excellent selectivity for removing methylene blue versus methyl orange in a binary system.					
36924868	9	52	theme	electrostatic	1317:1329	arg1	bonding					1341:1347	hydrogen bonding	1332:1347	hydrogen bonding	1332:1347	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	7	53	theme	Freundlich	1045:1054	arg1	isotherm					1056:1063	linear Freundlich isotherm	1038:1063	linear Freundlich isotherm	1038:1063	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	4	54	theme	achieved	534:541	arg1	beads					600:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads	530:604	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	7	55	theme	pseudo-2nd-order	1079:1094	arg1	models					1104:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	1	56	theme	Nowadays	141:148	arg1	challenge					157:165	Nowadays, a big challenge	141:165	challenge	157:165	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	7	57	theme	kinetic	1096:1102	arg1	models					1104:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	nonlinear pseudo-2nd-order kinetic models	1069:1109	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	6	58	theme	contact	857:863	arg1	time = 420 min					865:878	contact time = 420 min	857:878	contact time = 420 min	857:878	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	58	theme	contact	857:863	arg1	amount = 80 mg					797:810	adsorbent amount = 80 mg	787:810	adsorbent amount = 80 mg	787:810	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	58	theme	contact	857:863	arg1	pH = 6					779:784	pH = 6	779:784	pH = 6	779:784	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	58	theme	contact	857:863	arg1	concentration = 10 mg/L					828:850	methylene blue concentration = 10 mg/L	813:850	methylene blue concentration = 10 mg/L	813:850	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	6	58	theme	contact	857:863	arg1	parameters					905:914	optimal parameters	897:914	optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g	897:988	pH = 6, adsorbent amount = 80 mg, methylene blue concentration = 10 mg/L, and contact time = 420 min were achieved as optimal parameters on methylene blue adsorption with an adsorption capacity of about 26 mg/g.					
36924868	2	59	used	used	379:382	arg2	UiO-66-NH2					326:335	UiO-66-NH2	326:335	UiO-66-NH2	326:335	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	2	59	used	used	379:382	arg2	framework					315:323	Zr-based metal-organic framework	292:323	Zr-based metal-organic framework (UiO-66-NH2)	292:336	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	2	59	used	used	379:382	arg2	sawdust					342:348	sawdust	342:348	sawdust as the ideal adsorbents	342:372	In this regard, Zr-based metal-organic framework (UiO-66-NH2) and sawdust as the ideal adsorbents were used.					
36924868	9	60	dep	bonding	1341:1347	arg1	the					1313:1315	the	1313:1315	the	1313:1315	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	3	61	theme	composite	476:484	arg1	beads					486:490	composite beads	476:490	composite beads	476:490	Due to their low separation in adsorption processes, embedding into alginate and obtaining composite beads are suggested as a suitable strategy.					
36924868	5	62	theme	binary	764:769	arg1	system					771:776	a binary system	762:776	a binary system	762:776	This sorbent indicated an excellent selectivity for removing methylene blue versus methyl orange in a binary system.					
36924868	4	63	theme	anionic	640:646	arg1	removal					653:659	cationic and anionic dyes removal	627:659	cationic and anionic dyes removal	627:659	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	3	64	theme	suitable	511:518	arg1	strategy					520:527	a suitable strategy	509:527	a suitable strategy	509:527	Due to their low separation in adsorption processes, embedding into alginate and obtaining composite beads are suggested as a suitable strategy.					
36924868	4	65	theme	cationic	627:634	arg1	removal					653:659	cationic and anionic dyes removal	627:659	cationic and anionic dyes removal	627:659	The achieved Ca-alginate/citric acid (CA)-sawdust/UiO-66-NH2 hydrogel beads were used to compare cationic and anionic dyes removal.					
36924868	0	66	theme	dyes	54:57	arg1	removal					22:28	removal	22:28	removal of cationic and anionic dyes	22:57	Comparative study for removal of cationic and anionic dyes using alginate-based hydrogels filled with citric acid-sawdust/UiO-66-NH2 hybrid.					
36924868	9	67	theme	π-π	1354:1356	arg1	interactions					1358:1369	π-π interactions	1354:1369	π-π interactions	1354:1369	According to the outcomes, methylene blue could be attached to the adsorbent surface through the electrostatic, hydrogen bonding, and π-π interactions of the aromatic rings.					
36924868	7	68	theme	methylene	1014:1022	arg1	process					1003:1009	The removal process	991:1009	The removal process of methylene blue	991:1027	The removal process of methylene blue followed linear Freundlich isotherm and nonlinear pseudo-2nd-order kinetic models.					
36924868	1	69	theme	big	153:155	arg1	challenge					157:165	Nowadays, a big challenge	141:165	challenge	157:165	Nowadays, a big challenge is developing a sustainable and effective method for removing contaminants like dyes from aqueous solutions.					
36924868	8	70	theme	removal	1162:1168	arg1	efficiency					1170:1179	methylene blue removal efficiency	1147:1179	methylene blue removal efficiency higher than about 89 % after 9 cycles	1147:1217	The regeneration test demonstrated methylene blue removal efficiency higher than about 89 % after 9 cycles.					
36208813	3	0	with	CS-PLE	476:481	arg1	propertiese					519:529	antibacterial propertiese	505:529	antibacterial propertiese	505:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	3	0	with	CS-PLE	476:481	arg1	antioxidant					489:499	antioxidant	489:499	antioxidant	489:499	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	8	1	theme	CS-PLEs	1328:1334	arg1	study					1319:1323	the study	1315:1323	the study of CS-PLEs	1315:1334	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	2	2	theme	food	356:359	arg1	materials					371:379	biodegradable food packaging materials	342:379	biodegradable food packaging materials	342:379	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	4	3	theme	CS	725:726	arg1	film					728:731	CS film	725:731	CS film	725:731	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	5	4	theme	appending	1073:1081	arg1	proportion					1083:1092	the appending proportion	1069:1092	the appending proportion of PLE	1069:1099	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	4	5	theme	appropriate	812:822	arg1	protocols					837:845	appropriate experimental protocols	812:845	appropriate experimental protocols	812:845	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	2	6	theme	biodegradable	342:354	arg1	materials					371:379	biodegradable food packaging materials	342:379	biodegradable food packaging materials	342:379	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	4	7	theme	experimental	824:835	arg1	protocols					837:845	appropriate experimental protocols	812:845	appropriate experimental protocols	812:845	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	5	8	theme	total	958:962	arg1	content					973:979	total phenolic content	958:979	total phenolic content of CS film	958:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	3	9	theme	leaf	563:566	arg1	PLE					577:579	PLE	577:579	PLE	577:579	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	3	9	theme	leaf	563:566	arg1	extract					568:574	peony leaf extract	557:574	peony leaf extract (PLE)	557:580	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	2	10	theme	plant	300:304	arg1	extract					329:335	plant leaf (e.g. peony leaf) extract	300:335	plant leaf (e.g. peony leaf) extract	300:335	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	4	11	theme	PLE	791:793	arg1	concentrations					773:786	different concentrations	763:786	different concentrations of PLE	763:793	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	8	12	theme	environmental	1450:1462	arg1	pollution					1464:1472	environmental pollution	1450:1472	environmental pollution	1450:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	4	13	theme	series	698:703	arg1	properties					656:665	physical properties	647:665	physical properties	647:665	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	4	13	theme	series	698:703	arg1	activities					682:691	biological activities	671:691	biological activities	671:691	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	1	14	theme	leaf	59:62	arg1	film					82:85	leaf extract composite film	59:85	leaf extract composite film	59:85	leaf extract composite film and its application in sustainable active food packaging.					
36208813	3	15	theme	composite	460:468	arg1	CS-PLE					476:481	a novel green bioactive composite film (CS-PLE)	436:482	a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese	436:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	4	16	theme	physical	647:654	arg1	properties					656:665	physical properties	647:665	physical properties	647:665	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	4	17	theme	biological	671:680	arg1	activities					682:691	biological activities	671:691	biological activities	671:691	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	1	18	theme	extract	64:70	arg1	film					82:85	leaf extract composite film	59:85	leaf extract composite film	59:85	leaf extract composite film and its application in sustainable active food packaging.					
36208813	5	19	theme	PLE	890:892	arg1	addition					878:885	addition	878:885	addition of PLE	878:892	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	1	20	theme	composite	72:80	arg1	film					82:85	leaf extract composite film	59:85	leaf extract composite film	59:85	leaf extract composite film and its application in sustainable active food packaging.					
36208813	5	21	theme	CS	984:985	arg1	film					987:990	CS film	984:990	CS film	984:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	6	22	contain	had	1166:1168	arg1	CS-PLEs					1158:1164	CS-PLEs	1158:1164	CS-PLEs	1158:1164	Furthermore, CS-PLEs had better inhibiting effect on bacteria.					
36208813	6	22	contain	had	1166:1168	arg2	effect					1188:1193	better inhibiting effect	1170:1193	better inhibiting effect	1170:1193	Furthermore, CS-PLEs had better inhibiting effect on bacteria.					
36208813	6	23	theme	inhibiting	1177:1186	arg1	effect					1188:1193	better inhibiting effect	1170:1193	better inhibiting effect	1170:1193	Furthermore, CS-PLEs had better inhibiting effect on bacteria.					
36208813	5	24	theme	phenolic	964:971	arg1	content					973:979	total phenolic content	958:979	total phenolic content of CS film	958:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	2	25	theme	peony	317:321	arg1	leaf					323:326	peony leaf	317:326	peony leaf	317:326	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	5	26	theme	%	1053:1053	arg1	%					1062:1062	60.6 % ~ 73.2 %	1048:1062	60.6 % ~ 73.2 % with the appending proportion of PLE	1048:1099	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	8	27	theme	materials	1401:1409	arg1	preparation					1371:1381	the preparation	1367:1381	the preparation of food packaging materials that are green alternatives and reduce environmental pollution	1367:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	5	28	theme	%	1112:1112	arg1	%					1122:1122	0.1 wt% ~ 0.7 wt%	1106:1122	0.1 wt% ~ 0.7 wt% compared to CS film	1106:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	6	29	theme	better	1170:1175	arg1	effect					1188:1193	better inhibiting effect	1170:1193	better inhibiting effect	1170:1193	Furthermore, CS-PLEs had better inhibiting effect on bacteria.					
36208813	2	30	dep	leaf	323:326	arg1	e.g.					312:315	e.g.	312:315	e.g.	312:315	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	7	31	theme	CS-PLE	1217:1222	arg1	apples					1243:1248	CS-PLE (0.7 wt%) wrapping apples	1217:1248	CS-PLE (0.7 wt%) wrapping apples	1217:1248	Notably, CS-PLE (0.7 wt%) wrapping apples showed the least degree of browning among all the groups.					
36208813	5	32	theme	UV-A	949:952	arg1	performance					934:944	the barrier performance	922:944	the barrier performance of UV-A and total phenolic content of CS film	922:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	32	theme	UV-A	949:952	arg1	activities					1013:1022	the antioxidant activities	997:1022	the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film	997:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	32	theme	UV-A	949:952	arg1	stability					911:919	thermal stability	903:919	thermal stability	903:919	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	7	33	theme	browning	1277:1284	arg1	degree					1267:1272	the least degree	1257:1272	the least degree of browning among all the groups	1257:1305	Notably, CS-PLE (0.7 wt%) wrapping apples showed the least degree of browning among all the groups.					
36208813	5	34	theme	 ~ 0.7 wt	1113:1121	arg1	%					1122:1122	0.1 wt% ~ 0.7 wt%	1106:1122	0.1 wt% ~ 0.7 wt% compared to CS film	1106:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	7	35	theme	least	1261:1265	arg1	degree					1267:1272	the least degree	1257:1272	the least degree of browning among all the groups	1257:1305	Notably, CS-PLE (0.7 wt%) wrapping apples showed the least degree of browning among all the groups.					
36208813	4	36	theme	films	708:712	arg1	series					698:703	a series	696:703	a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE,	696:794	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	3	37	theme	novel	438:442	arg1	CS-PLE					476:481	a novel green bioactive composite film (CS-PLE)	436:482	a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese	436:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	0	38	theme	chitosan/peony	15:28	arg1	Preparation					0:10	Preparation	0:10	Preparation of chitosan/peony (Paeonia suffruticosa Andr.)	0:57	Preparation of chitosan/peony (Paeonia suffruticosa Andr.)					
36208813	2	39	theme	perishability	177:189	arg1	problem					161:167	the problem	157:167	the problem of food perishability	157:189	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	2	39	theme	perishability	177:189	arg1	pollution					213:221	the environmental pollution	195:221	the environmental pollution of plastic packaging	195:242	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	2	40	theme	leaf	306:309	arg1	extract					329:335	plant leaf (e.g. peony leaf) extract	300:335	plant leaf (e.g. peony leaf) extract	300:335	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	5	41	theme	film	987:990	arg1	content					973:979	total phenolic content	958:979	total phenolic content of CS film	958:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	41	theme	film	987:990	arg1	UV-A					949:952	UV-A	949:952	UV-A	949:952	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	3	42	theme	green	444:448	arg1	CS-PLE					476:481	a novel green bioactive composite film (CS-PLE)	436:482	a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese	436:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	5	43	theme	barrier	926:932	arg1	performance					934:944	the barrier performance	922:944	the barrier performance of UV-A and total phenolic content of CS film	922:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	7	44	dep	CS-PLE	1217:1222	arg1	%					1231:1231	0.7 wt%	1225:1231	0.7 wt%	1225:1231	Notably, CS-PLE (0.7 wt%) wrapping apples showed the least degree of browning among all the groups.					
36208813	2	45	theme	food	172:175	arg1	perishability					177:189	food perishability	172:189	food perishability	172:189	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	5	46	theme	content	973:979	arg1	performance					934:944	the barrier performance	922:944	the barrier performance of UV-A and total phenolic content of CS film	922:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	46	theme	content	973:979	arg1	activities					1013:1022	the antioxidant activities	997:1022	the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film	997:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	46	theme	content	973:979	arg1	stability					911:919	thermal stability	903:919	thermal stability	903:919	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	7	47	theme	wrapping	1234:1241	arg1	apples					1243:1248	CS-PLE (0.7 wt%) wrapping apples	1217:1248	CS-PLE (0.7 wt%) wrapping apples	1217:1248	Notably, CS-PLE (0.7 wt%) wrapping apples showed the least degree of browning among all the groups.					
36208813	3	48	theme	peony	557:561	arg1	PLE					577:579	PLE	577:579	PLE	577:579	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	3	48	theme	peony	557:561	arg1	extract					568:574	peony leaf extract	557:574	peony leaf extract (PLE)	557:580	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	5	49	theme	CS	1136:1137	arg1	film					1139:1142	CS film	1136:1142	CS film	1136:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	8	50	theme	new	1350:1352	arg1	strategy					1354:1361	a new strategy	1348:1361	a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution	1348:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	2	51	theme	packaging	234:242	arg1	problem					161:167	the problem	157:167	the problem of food perishability	157:189	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	2	51	theme	packaging	234:242	arg1	pollution					213:221	the environmental pollution	195:221	the environmental pollution of plastic packaging	195:242	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	5	52	theme	PLE	1097:1099	arg1	proportion					1083:1092	the appending proportion	1069:1092	the appending proportion of PLE	1069:1099	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	2	53	theme	plastic	226:232	arg1	packaging					234:242	plastic packaging	226:242	plastic packaging	226:242	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	3	54	theme	film	470:473	arg1	CS-PLE					476:481	a novel green bioactive composite film (CS-PLE)	436:482	a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese	436:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	8	55	theme	packaging	1391:1399	arg1	materials					1401:1409	food packaging materials	1386:1409	food packaging materials that are green alternatives and reduce environmental pollution	1386:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	8	55	theme	packaging	1391:1399	arg1	alternatives					1426:1437	green alternatives	1420:1437	green alternatives	1420:1437	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	3	56	theme	casting	627:633	arg1	method					635:640	the solution casting method	614:640	the solution casting method	614:640	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	1	57	theme	sustainable	110:120	arg1	packaging					134:142	sustainable active food packaging	110:142	sustainable active food packaging	110:142	leaf extract composite film and its application in sustainable active food packaging.					
36208813	5	58	theme	0.1 wt	1106:1111	arg1	%					1122:1122	0.1 wt% ~ 0.7 wt%	1106:1122	0.1 wt% ~ 0.7 wt% compared to CS film	1106:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	59	theme	thermal	903:909	arg1	stability					911:919	thermal stability	903:919	thermal stability	903:919	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	2	60	theme	environmental	199:211	arg1	pollution					213:221	the environmental pollution	195:221	the environmental pollution of plastic packaging	195:242	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	3	61	theme	chitosan	587:594	arg1	film					601:604	chitosan (CS) film	587:604	chitosan (CS) film	587:604	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	4	62	theme	different	763:771	arg1	concentrations					773:786	different concentrations	763:786	different concentrations of PLE	763:793	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36208813	1	63	theme	active	122:127	arg1	packaging					134:142	sustainable active food packaging	110:142	sustainable active food packaging	110:142	leaf extract composite film and its application in sustainable active food packaging.					
36208813	1	64	from	application	95:105	arg1	packaging					134:142	sustainable active food packaging	110:142	sustainable active food packaging	110:142	leaf extract composite film and its application in sustainable active food packaging.					
36208813	3	65	theme	antibacterial	505:517	arg1	propertiese					519:529	antibacterial propertiese	505:529	antibacterial propertiese	505:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	5	66	theme	antioxidant	1001:1011	arg1	activities					1013:1022	the antioxidant activities	997:1022	the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film	997:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	2	67	theme	active	257:262	arg1	key					390:392	key	390:392	key	390:392	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	2	67	theme	active	257:262	arg1	packaging					264:272	the natural active packaging	245:272	the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials	245:379	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	5	68	theme	CS-PLEs	1027:1033	arg1	performance					934:944	the barrier performance	922:944	the barrier performance of UV-A and total phenolic content of CS film	922:990	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	68	theme	CS-PLEs	1027:1033	arg1	activities					1013:1022	the antioxidant activities	997:1022	the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film	997:1142	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	5	68	theme	CS-PLEs	1027:1033	arg1	stability					911:919	thermal stability	903:919	thermal stability	903:919	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	1	69	theme	food	129:132	arg1	packaging					134:142	sustainable active food packaging	110:142	sustainable active food packaging	110:142	leaf extract composite film and its application in sustainable active food packaging.					
36208813	1	70	from	film	82:85	arg1	packaging					134:142	sustainable active food packaging	110:142	sustainable active food packaging	110:142	leaf extract composite film and its application in sustainable active food packaging.					
36208813	3	71	theme	bioactive	450:458	arg1	CS-PLE					476:481	a novel green bioactive composite film (CS-PLE)	436:482	a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese	436:529	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	3	72	theme	solution	618:625	arg1	method					635:640	the solution casting method	614:640	the solution casting method	614:640	In the study, a novel green bioactive composite film (CS-PLE) with antioxidant and antibacterial propertiese was developed by blending peony leaf extract (PLE) into chitosan (CS) film through the solution casting method.					
36208813	2	73	theme	natural	249:255	arg1	key					390:392	key	390:392	key	390:392	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	2	73	theme	natural	249:255	arg1	packaging					264:272	the natural active packaging	245:272	the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials	245:379	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	8	74	theme	green	1420:1424	arg1	materials					1401:1409	food packaging materials	1386:1409	food packaging materials that are green alternatives and reduce environmental pollution	1386:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	8	74	theme	green	1420:1424	arg1	alternatives					1426:1437	green alternatives	1420:1437	green alternatives	1420:1437	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	5	75	with	%	1062:1062	arg1	proportion					1083:1092	the appending proportion	1069:1092	the appending proportion of PLE	1069:1099	The results demonstrated that addition of PLE improved thermal stability, the barrier performance of UV-A and total phenolic content of CS film, and the antioxidant activities of CS-PLEs increased by 60.6 % ~ 73.2 % with the appending proportion of PLE from 0.1 wt% ~ 0.7 wt% compared to CS film.					
36208813	8	76	theme	food	1386:1389	arg1	materials					1401:1409	food packaging materials	1386:1409	food packaging materials that are green alternatives and reduce environmental pollution	1386:1472	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	8	76	theme	food	1386:1389	arg1	alternatives					1426:1437	green alternatives	1420:1437	green alternatives	1420:1437	Hence, the study of CS-PLEs can provide a new strategy for the preparation of food packaging materials that are green alternatives and reduce environmental pollution.					
36208813	0	77	dep	Preparation	0:10	arg1	Andr					52:55	Andr	52:55	Andr	52:55	Preparation of chitosan/peony (Paeonia suffruticosa Andr.)					
36208813	2	78	theme	packaging	361:369	arg1	materials					371:379	biodegradable food packaging materials	342:379	biodegradable food packaging materials	342:379	Considering the problem of food perishability and the environmental pollution of plastic packaging, the natural active packaging prepared by incorporating plant leaf (e.g. peony leaf) extract into biodegradable food packaging materials may be a key to addressing these issues.					
36208813	4	79	dep	properties	656:665	arg1	The					643:645	The	643:645	The	643:645	The physical properties and biological activities of a series of films, including CS film and CS-PLEs incorporated with different concentrations of PLE, were studied by appropriate experimental protocols.					
36906206	1	0	from	AMG	348:350	arg1	study					360:364	this study	355:364	this study	355:364	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	0	1	theme	gel	165:167	arg1	properties					106:115	the texture and rheology properties	81:115	the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel	81:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	5	2	theme	composite	1041:1049	arg1	gels					1051:1054	KGM/AMG composite gels	1033:1054	KGM/AMG composite gels	1033:1054	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	6	3	theme	potential	1100:1108	arg1	value					1119:1123	the zeta potential absolute value	1091:1123	the zeta potential absolute value	1091:1123	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	4	4	dep	2.0 	875:878	arg1	to					872:873	to	872:873	to	872:873	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	2	5	dep	spectroscopy	521:532	arg1	analysis					608:615	analysis	608:615	analysis	608:615	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	3	6	theme	AMG	649:651	arg1	content					653:659	the AMG content	645:659	the AMG content	645:659	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	6	7	theme	ions	1078:1081	arg1	addition					1061:1068	The addition	1057:1068	The addition of salt ions	1057:1081	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	4	8	theme	G	792:792	arg1	*					793:793	G*	792:793	G*	792:793	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	0	9	theme	rheology	97:104	arg1	properties					106:115	the texture and rheology properties	81:115	the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel	81:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	1	10	theme	gelling	185:191	arg1	property					193:200	the gelling property	181:200	the gelling property of konjac gum (KGM)	181:220	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	7	11	theme	KGM/AMG	1221:1227	arg1	gels					1239:1242	the KGM/AMG composite gels	1217:1242	the KGM/AMG composite gels	1217:1242	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	7	11	theme	KGM/AMG	1221:1227	arg1	gels					1280:1283	non-covalent gels	1267:1283	non-covalent gels	1267:1283	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	6	12	theme	rheological	1154:1164	arg1	properties					1166:1175	rheological properties	1154:1175	rheological properties	1154:1175	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	1	13	theme	gel	317:319	arg1	type					309:312	a novel type	301:312	a novel type of gel	301:319	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	2	14	dep	transform	502:510	arg1	infrared					512:519	infrared	512:519	transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis	502:615	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	0	15	theme	gum/Abelmoschus	127:141	arg1	gel					165:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	3	16	theme	gels	747:750	arg1	strength					717:724	the gel strength	709:724	the gel strength of KGM/AMG composite gels	709:750	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	2	17	theme	composite	463:471	arg1	gels					473:476	KGM/AMG composite gels	455:476	KGM/AMG composite gels	455:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	8	18	theme	hydrogen	1321:1328	arg1	bonding					1330:1336	hydrogen bonding	1321:1336	hydrogen bonding	1321:1336	The non-covalent linkages included hydrogen bonding and electrostatic interactions.					
36906206	2	19	theme	dynamic	579:585	arg1	behavior					599:606	dynamic rheological behavior	579:606	dynamic rheological behavior	579:606	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	9	20	dep	properties	1411:1420	arg1	the					1407:1409	the	1407:1409	the	1407:1409	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	0	21	theme	gum	151:153	arg1	gel					165:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	3	22	theme	KGM/AMG	729:735	arg1	gels					747:750	KGM/AMG composite gels	729:750	KGM/AMG composite gels	729:750	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	4	23	theme	gels	823:826	arg1	*					793:793	G*	792:793	G*	792:793	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	23	theme	gels	823:826	arg1	resilience					776:785	resilience	776:785	resilience	776:785	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	23	theme	gels	823:826	arg1	G					788:788	G'	788:789	G'	788:789	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	23	theme	gels	823:826	arg1	*					800:800	η*	799:800	η*	799:800	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	23	theme	gels	823:826	arg1	Hardness					753:760	Hardness	753:760	Hardness	753:760	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	23	theme	gels	823:826	arg1	springiness					763:773	springiness	763:773	springiness	763:773	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	3	24	theme	salt	686:689	arg1	ions					691:694	salt ions	686:694	salt ions	686:694	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	0	25	theme	temperature	52:62	arg1	Effects					0:6	Effects	0:6	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.	0:168	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	1	26	theme	medic	284:288	arg1	AMG					295:297	AMG	295:297	AMG	295:297	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	26	theme	medic	284:288	arg1	gum					290:292	Abelmoschus manihot (L.) medic gum	259:292	Abelmoschus manihot (L.) medic gum (AMG)	259:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	2	27	theme	content	386:392	arg1	effects					371:377	The effects	367:377	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels	367:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	0	28	theme	salt	68:71	arg1	ions					73:76	salt ions	68:76	salt ions	68:76	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	5	29	theme	High-temperature	941:956	arg1	treatment					958:966	High-temperature treatment	941:966	High-temperature treatment	941:966	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	2	30	theme	ions	424:427	arg1	effects					371:377	The effects	367:377	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels	367:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	0	31	from	Effects	0:6	arg1	properties					106:115	the texture and rheology properties	81:115	the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel	81:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	2	32	theme	zeta	542:545	arg1	potential					547:555	zeta potential	542:555	zeta potential	542:555	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	4	33	theme	KGM/AMG	805:811	arg1	gels					823:826	KGM/AMG composite gels	805:826	KGM/AMG composite gels	805:826	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	5	34	dep	texture	995:1001	arg1	the					991:993	the	991:993	the	991:993	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	0	35	theme	texture	85:91	arg1	properties					106:115	the texture and rheology properties	81:115	the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel	81:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	2	36	from	effects	371:377	arg1	characteristics					436:450	the characteristics	432:450	the characteristics of KGM/AMG composite gels	432:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	2	37	theme	heating	395:401	arg1	temperature					403:413	heating temperature	395:413	heating temperature	395:413	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	1	38	theme	application	238:248	arg1	value					250:254	the application value	234:254	the application value of Abelmoschus manihot (L.) medic gum (AMG)	234:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	9	39	theme	KGM/AMG	1449:1455	arg1	gels					1467:1470	KGM/AMG composite gels	1449:1470	KGM/AMG composite gels	1449:1470	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	0	40	theme	Abelmoschus	11:21	arg1	content					35:41	Abelmoschus manihot gum content	11:41	Abelmoschus manihot gum content	11:41	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	9	41	theme	gels	1467:1470	arg1	properties					1411:1420	properties	1411:1420	properties	1411:1420	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	9	41	theme	gels	1467:1470	arg1	mechanism					1436:1444	formation mechanism	1426:1444	formation mechanism	1426:1444	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	0	42	theme	gum	31:33	arg1	content					35:41	Abelmoschus manihot gum content	11:41	Abelmoschus manihot gum content	11:41	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	1	43	theme	manihot	271:277	arg1	AMG					295:297	AMG	295:297	AMG	295:297	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	43	theme	manihot	271:277	arg1	gum					290:292	Abelmoschus manihot (L.) medic gum	259:292	Abelmoschus manihot (L.) medic gum (AMG)	259:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	44	theme	L.	280:281	arg1	AMG					295:297	AMG	295:297	AMG	295:297	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	44	theme	L.	280:281	arg1	gum					290:292	Abelmoschus manihot (L.) medic gum	259:292	Abelmoschus manihot (L.) medic gum (AMG)	259:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	45	theme	konjac	205:210	arg1	KGM					217:219	KGM	217:219	KGM	217:219	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	45	theme	konjac	205:210	arg1	gum					212:214	konjac gum	205:214	konjac gum (KGM)	205:220	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	9	46	theme	KGM	1514:1516	arg1	value					1505:1509	the application value	1489:1509	the application value of KGM and AMG	1489:1524	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	5	47	theme	KGM/AMG	1033:1039	arg1	gels					1051:1054	KGM/AMG composite gels	1033:1054	KGM/AMG composite gels	1033:1054	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	9	48	theme	AMG	1522:1524	arg1	value					1505:1509	the application value	1489:1509	the application value of KGM and AMG	1489:1524	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	6	49	theme	absolute	1110:1117	arg1	value					1119:1123	the zeta potential absolute value	1091:1123	the zeta potential absolute value	1091:1123	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	5	50	theme	gels	1051:1054	arg1	texture					995:1001	texture	995:1001	texture	995:1001	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	5	50	theme	gels	1051:1054	arg1	properties					1019:1028	rheological properties	1007:1028	rheological properties	1007:1028	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	6	51	theme	zeta	1095:1098	arg1	value					1119:1123	the zeta potential absolute value	1091:1123	the zeta potential absolute value	1091:1123	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	7	52	theme	non-covalent	1267:1278	arg1	gels					1239:1242	the KGM/AMG composite gels	1217:1242	the KGM/AMG composite gels	1217:1242	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	7	52	theme	non-covalent	1267:1278	arg1	gels					1280:1283	non-covalent gels	1267:1283	non-covalent gels	1267:1283	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	4	53	theme	%	929:929	arg1	%					938:938	2.0 % to 3.5 %	925:938	2.0 % to 3.5 %	925:938	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	6	54	theme	KGM/AMG	1180:1186	arg1	gels					1198:1201	KGM/AMG composite gels	1180:1201	KGM/AMG composite gels	1180:1201	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	6	55	dep	texture	1142:1148	arg1	the					1138:1140	the	1138:1140	the	1138:1140	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	8	56	theme	non-covalent	1290:1301	arg1	linkages					1303:1310	The non-covalent linkages	1286:1310	The non-covalent linkages	1286:1310	The non-covalent linkages included hydrogen bonding and electrostatic interactions.					
36906206	0	57	theme	konjac	120:125	arg1	gel					165:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	7	58	theme	composite	1229:1237	arg1	gels					1239:1242	the KGM/AMG composite gels	1217:1242	the KGM/AMG composite gels	1217:1242	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	7	58	theme	composite	1229:1237	arg1	gels					1280:1283	non-covalent gels	1267:1283	non-covalent gels	1267:1283	Furthermore, the KGM/AMG composite gels could be classified as non-covalent gels.					
36906206	0	59	theme	manihot	143:149	arg1	gel					165:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	2	60	dep	Fourier	494:500	arg1	transform					502:510	transform	502:510	transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis	502:615	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	2	61	theme	gels	473:476	arg1	characteristics					436:450	the characteristics	432:450	the characteristics of KGM/AMG composite gels	432:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	2	62	theme	rheological	587:597	arg1	behavior					599:606	dynamic rheological behavior	579:606	dynamic rheological behavior	579:606	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	3	63	theme	heating	662:668	arg1	temperature					670:680	heating temperature	662:680	heating temperature	662:680	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	0	64	theme	composite	155:163	arg1	gel					165:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	konjac gum/Abelmoschus manihot gum composite gel	120:167	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	2	65	theme	KGM/AMG	455:461	arg1	gels					473:476	KGM/AMG composite gels	455:476	KGM/AMG composite gels	455:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	8	66	theme	electrostatic	1342:1354	arg1	interactions					1356:1367	electrostatic interactions	1342:1367	electrostatic interactions	1342:1367	The non-covalent linkages included hydrogen bonding and electrostatic interactions.					
36906206	1	67	from	KGM	340:342	arg1	study					360:364	this study	355:364	this study	355:364	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	3	68	theme	composite	737:745	arg1	gels					747:750	KGM/AMG composite gels	729:750	KGM/AMG composite gels	729:750	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	4	69	theme	composite	813:821	arg1	gels					823:826	KGM/AMG composite gels	805:826	KGM/AMG composite gels	805:826	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	4	70	theme	η	799:799	arg1	*					800:800	η*	799:800	η*	799:800	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	0	71	theme	ions	73:76	arg1	Effects					0:6	Effects	0:6	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.	0:168	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	1	72	theme	gum	290:292	arg1	value					250:254	the application value	234:254	the application value of Abelmoschus manihot (L.) medic gum (AMG)	234:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	4	73	dep	%	938:938	arg1	to					931:932	to	931:932	to	931:932	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	2	74	theme	AMG	382:384	arg1	content					386:392	AMG content	382:392	AMG content	382:392	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	2	75	theme	salt	419:422	arg1	ions					424:427	salt ions	419:427	salt ions	419:427	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	3	76	theme	gel	713:715	arg1	strength					717:724	the gel strength	709:724	the gel strength of KGM/AMG composite gels	709:750	The results indicated that the AMG content, heating temperature and salt ions could affect the gel strength of KGM/AMG composite gels.					
36906206	6	77	theme	gels	1198:1201	arg1	texture					1142:1148	texture	1142:1148	texture	1142:1148	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	6	77	theme	gels	1198:1201	arg1	properties					1166:1175	rheological properties	1154:1175	rheological properties	1154:1175	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	9	78	theme	formation	1426:1434	arg1	mechanism					1436:1444	formation mechanism	1426:1444	formation mechanism	1426:1444	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	2	79	theme	temperature	403:413	arg1	effects					371:377	The effects	367:377	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels	367:476	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	1	80	theme	novel	303:307	arg1	type					309:312	a novel type	301:312	a novel type of gel	301:319	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	2	81	theme	texture	558:564	arg1	analysis					566:573	texture analysis	558:573	texture analysis	558:573	The effects of AMG content, heating temperature and salt ions on the characteristics of KGM/AMG composite gels were studied by Fourier transform infrared spectroscopy (FTIR), zeta potential, texture analysis and dynamic rheological behavior analysis.					
36906206	0	82	theme	manihot	23:29	arg1	content					35:41	Abelmoschus manihot gum content	11:41	Abelmoschus manihot gum content	11:41	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	5	83	theme	rheological	1007:1017	arg1	properties					1019:1028	rheological properties	1007:1028	rheological properties	1007:1028	High-temperature treatment significantly enhanced the texture and rheological properties of KGM/AMG composite gels.					
36906206	9	84	theme	composite	1457:1465	arg1	gels					1467:1470	KGM/AMG composite gels	1449:1470	KGM/AMG composite gels	1449:1470	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	6	85	theme	salt	1073:1076	arg1	ions					1078:1081	salt ions	1073:1081	salt ions	1073:1081	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	0	86	theme	content	35:41	arg1	Effects					0:6	Effects	0:6	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.	0:168	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	1	87	theme	Abelmoschus	259:269	arg1	AMG					295:297	AMG	295:297	AMG	295:297	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	1	87	theme	Abelmoschus	259:269	arg1	gum					290:292	Abelmoschus manihot (L.) medic gum	259:292	Abelmoschus manihot (L.) medic gum (AMG)	259:298	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36906206	4	88	theme	AMG	843:845	arg1	content					847:853	AMG content	843:853	AMG content	843:853	Hardness, springiness, resilience, G', G* and η* of KGM/AMG composite gels increased when AMG content increased from 0 to 2.0 %, but they decreased when AMG increased from 2.0 % to 3.5 %.					
36906206	6	89	theme	composite	1188:1196	arg1	gels					1198:1201	KGM/AMG composite gels	1180:1201	KGM/AMG composite gels	1180:1201	The addition of salt ions reduced the zeta potential absolute value and weakened the texture and rheological properties of KGM/AMG composite gels.					
36906206	0	90	theme	heating	44:50	arg1	temperature					52:62	heating temperature	44:62	heating temperature	44:62	Effects of Abelmoschus manihot gum content, heating temperature and salt ions on the texture and rheology properties of konjac gum/Abelmoschus manihot gum composite gel.					
36906206	9	91	theme	application	1493:1503	arg1	value					1505:1509	the application value	1489:1509	the application value of KGM and AMG	1489:1524	These findings would help understand the properties and formation mechanism of KGM/AMG composite gels and help improve the application value of KGM and AMG.					
36906206	1	92	theme	gum	212:214	arg1	property					193:200	the gelling property	181:200	the gelling property of konjac gum (KGM)	181:220	To improve the gelling property of konjac gum (KGM) and enhance the application value of Abelmoschus manihot (L.) medic gum (AMG), a novel type of gel was prepared using KGM and AMG in this study.					
36427613	0	0	theme	eliminating	103:113	arg1	biofilm					115:121	eliminating biofilm and multidrug-resistant bacteria	103:154	biofilm	115:121	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	3	1	theme	based	759:763	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	4	2	theme	good	915:918	arg1	degradability					920:932	good degradability	915:932	good degradability	915:932	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	1	3	theme	wound	202:206	arg1	infection					208:216	wound infection	202:216	wound infection	202:216	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	7	4	theme	wound	1520:1524	arg1	healing					1526:1532	the best wound healing	1511:1532	the best wound healing rate	1511:1537	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	8	5	theme	multifunctional	1623:1637	arg1	hydrogel					1639:1646	the multifunctional hydrogel	1619:1646	the multifunctional hydrogel	1619:1646	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	2	6	theme	prolonged	535:543	arg1	unhealing					545:553	prolonged unhealing	535:553	prolonged unhealing	535:553	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	5	7	theme	CAC/PDA/Cu	949:958	arg1	hydrogel					966:973	the CAC/PDA/Cu(H2O2) hydrogel	945:973	the CAC/PDA/Cu(H2O2) hydrogel	945:973	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	5	8	theme	anti-inflammatory	1015:1031	arg1	effects					1033:1039	antibacterial, and anti-inflammatory effects	996:1039	antibacterial, and anti-inflammatory effects	996:1039	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	3	9	theme	Alg	754:756	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	2	10	theme	corresponding	335:347	arg1	functions					360:368	corresponding biological functions	335:368	corresponding biological functions	335:368	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	3	11	theme	multifunctional	614:628	arg1	hydrogel					630:637	a multifunctional hydrogel	612:637	a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2)	612:800	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	7	12	theme	CAC/PDA/Cu	1475:1484	arg1	hydrogel					1492:1499	CAC/PDA/Cu(H2O2) hydrogel	1475:1499	CAC/PDA/Cu(H2O2) hydrogel	1475:1499	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	5	13	theme	PDA/Cu	1133:1138	arg1	coatings					1146:1153	the composite PDA/Cu(H2O2) coatings	1119:1153	the composite PDA/Cu(H2O2) coatings	1119:1153	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	6	14	theme	excellent	1209:1217	arg1	effects					1231:1237	excellent therapeutic effects	1209:1237	excellent therapeutic effects	1209:1237	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	8	15	from	potential	1734:1742	arg1	therapy					1751:1757	the therapy	1747:1757	the therapy for wound healing	1747:1775	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	8	16	theme	promising	1724:1732	arg1	potential					1734:1742	promising potential	1724:1742	promising potential in the therapy for wound healing	1724:1775	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	7	17	theme	healing	1526:1532	arg1	rate					1534:1537	the best wound healing rate	1511:1537	the best wound healing rate	1511:1537	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	6	18	dep	illustrates	1197:1207	arg1	reduce					1374:1379	reduce	1374:1379	reduce inflammatory expression	1374:1403	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	6	18	dep	illustrates	1197:1207	arg1	shorten					1443:1449	shorten	1443:1449	shorten the wound healing time	1443:1472	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	6	18	dep	illustrates	1197:1207	arg1	promote					1406:1412	promote	1406:1412	promote angiogenesis	1406:1425	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	4	19	theme	mechanical	888:897	arg1	properties					899:908	adequate mechanical properties	879:908	adequate mechanical properties	879:908	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	4	20	theme	CAC/PDA/Cu	816:825	arg1	features					842:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	5	21	theme	composite	1123:1131	arg1	H2O2					1140:1143	H2O2	1140:1143	H2O2	1140:1143	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	5	21	theme	composite	1123:1131	arg1	PDA/Cu					1133:1138	the composite PDA/Cu	1119:1138	the composite PDA/Cu(H2O2) coatings	1119:1153	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	0	22	theme	multidrug-resistant	127:145	arg1	bacteria					147:154	eliminating biofilm and multidrug-resistant bacteria	103:154	bacteria	147:154	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	4	23	theme	adequate	879:886	arg1	properties					899:908	adequate mechanical properties	879:908	adequate mechanical properties	879:908	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	4	24	theme	prepared	807:814	arg1	features					842:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	2	25	theme	vascular	505:512	arg1	damage					514:519	vascular damage	505:519	vascular damage	505:519	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	7	26	theme	best	1515:1518	arg1	healing					1526:1532	the best wound healing	1511:1532	the best wound healing rate	1511:1537	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	6	27	theme	infection	1305:1313	arg1	models					1315:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	2	28	theme	traditional	371:381	arg1	dressings					389:397	traditional wound dressings	371:397	traditional wound dressings	371:397	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	3	29	from	deposition	694:703	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	1	30	theme	accompanying	226:237	arg1	response					262:269	the accompanying excessive inflammatory response	222:269	the accompanying excessive inflammatory response	222:269	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	1	30	theme	accompanying	226:237	arg1	problems					287:294	the daunting problems	274:294	the daunting problems in wound treatment	274:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	0	31	theme	Carboxymethyl	0:12	arg1	hydrogels					39:47	Carboxymethyl chitosan/sodium alginate hydrogels	0:47	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria	0:154	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	6	32	theme	induced-rat	1293:1303	arg1	models					1315:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	5	33	theme	wound	1086:1090	arg1	healing					1092:1098	wound healing	1086:1098	wound healing	1086:1098	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	1	34	theme	excessive	239:247	arg1	response					262:269	the accompanying excessive inflammatory response	222:269	the accompanying excessive inflammatory response	222:269	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	1	34	theme	excessive	239:247	arg1	problems					287:294	the daunting problems	274:294	the daunting problems in wound treatment	274:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	0	35	theme	wound	164:168	arg1	healing					170:176	wound healing	164:176	wound healing	164:176	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	6	36	theme	aureus	1279:1284	arg1	models					1315:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models	1242:1320	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	2	37	theme	functions	360:368	arg1	lack					327:330	the lack	323:330	the lack of corresponding biological functions	323:368	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	4	38	theme	excellent	851:859	arg1	biocompatibility					861:876	excellent biocompatibility	851:876	excellent biocompatibility	851:876	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	2	39	theme	excessive	477:485	arg1	inflammation					487:498	excessive inflammation	477:498	excessive inflammation	477:498	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	0	40	theme	alginate	30:37	arg1	hydrogels					39:47	Carboxymethyl chitosan/sodium alginate hydrogels	0:47	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria	0:154	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	6	41	theme	therapeutic	1219:1229	arg1	effects					1231:1237	excellent therapeutic effects	1209:1237	excellent therapeutic effects	1209:1237	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	7	42	theme	H2O2	1486:1489	arg1	hydrogel					1492:1499	CAC/PDA/Cu(H2O2) hydrogel	1475:1499	CAC/PDA/Cu(H2O2) hydrogel	1475:1499	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	3	43	theme	chitosan	722:729	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	2	44	theme	biological	349:358	arg1	functions					360:368	corresponding biological functions	335:368	corresponding biological functions	335:368	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	4	45	dep	biocompatibility	861:876	arg1	features					842:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	0	46	theme	polydopamine	54:65	arg1	coatings					67:74	polydopamine coatings	54:74	polydopamine coatings	54:74	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	3	47	theme	rapid	669:673	arg1	PDA					689:691	PDA	689:691	PDA	689:691	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	3	47	theme	rapid	669:673	arg1	polydopamine					675:686	rapid polydopamine	669:686	H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2)	650:800	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	6	48	theme	wound	1455:1459	arg1	healing					1461:1467	the wound healing	1451:1467	the wound healing time	1451:1472	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	6	49	theme	inflammatory	1381:1392	arg1	expression					1394:1403	inflammatory expression	1381:1403	inflammatory expression	1381:1403	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	3	50	theme	polydopamine	675:686	arg1	deposition					694:703	H2O2/CuSO4-induced rapid polydopamine (PDA) deposition	650:703	H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2)	650:800	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	0	51	with	hydrogels	39:47	arg1	coatings					67:74	polydopamine coatings	54:74	polydopamine coatings	54:74	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	2	52	theme	local	460:464	arg1	infection					466:474	local infection	460:474	local infection	460:474	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	3	53	theme	carboxymethyl	708:720	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	8	54	theme	wound	1763:1767	arg1	healing					1769:1775	wound healing	1763:1775	wound healing	1763:1775	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	3	55	theme	/sodium	736:742	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	3	56	theme	H2O2/CuSO4-induced	650:667	arg1	deposition					694:703	H2O2/CuSO4-induced rapid polydopamine (PDA) deposition	650:703	H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2)	650:800	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	5	57	theme	H2O2	960:963	arg1	hydrogel					966:973	the CAC/PDA/Cu(H2O2) hydrogel	945:973	the CAC/PDA/Cu(H2O2) hydrogel	945:973	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	8	58	theme	facile	1659:1664	arg1	approach					1680:1687	a facile and efficient approach	1657:1687	a facile and efficient approach to wound management	1657:1707	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	3	59	theme	alginate	744:751	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	1	60	theme	daunting	278:285	arg1	response					262:269	the accompanying excessive inflammatory response	222:269	the accompanying excessive inflammatory response	222:269	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	1	60	theme	daunting	278:285	arg1	problems					287:294	the daunting problems	274:294	the daunting problems in wound treatment	274:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	1	61	from	problems	287:294	arg1	treatment					305:313	wound treatment	299:313	wound treatment	299:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	3	62	theme	CMC	732:734	arg1	hydrogel					765:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel	708:772	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	5	63	theme	antibacterial	996:1008	arg1	effects					1033:1039	antibacterial, and anti-inflammatory effects	996:1039	antibacterial, and anti-inflammatory effects	996:1039	Moreover, the CAC/PDA/Cu(H2O2) hydrogel can not only realize antibacterial, and anti-inflammatory effects, but also promote angiogenesis to accelerate wound healing in vitro thanks to the composite PDA/Cu(H2O2) coatings.					
36427613	2	64	theme	wound	383:387	arg1	dressings					389:397	traditional wound dressings	371:397	traditional wound dressings	371:397	Due to the lack of corresponding biological functions, traditional wound dressings cannot effectively protect the wound and are prone to induce local infection, excessive inflammation, and vascular damage, resulting in prolonged unhealing.					
36427613	8	65	theme	efficient	1670:1678	arg1	approach					1680:1687	a facile and efficient approach	1657:1687	a facile and efficient approach to wound management	1657:1707	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	6	66	theme	healing	1461:1467	arg1	time					1469:1472	the wound healing time	1451:1472	the wound healing time	1451:1472	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	8	67	theme	wound	1692:1696	arg1	management					1698:1707	wound management	1692:1707	wound management	1692:1707	Thus, the multifunctional hydrogel provides a facile and efficient approach to wound management and represents promising potential in the therapy for wound healing.					
36427613	4	68	theme	hydrogel	833:840	arg1	features					842:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features	803:849	The prepared CAC/PDA/Cu(H2O2) hydrogel features excellent biocompatibility, adequate mechanical properties, and good degradability.					
36427613	1	69	theme	inflammatory	249:260	arg1	response					262:269	the accompanying excessive inflammatory response	222:269	the accompanying excessive inflammatory response	222:269	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	1	69	theme	inflammatory	249:260	arg1	problems					287:294	the daunting problems	274:294	the daunting problems in wound treatment	274:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
36427613	3	70	theme	mussel-inspired	564:578	arg1	strategy					580:587	a mussel-inspired strategy	562:587	a mussel-inspired strategy	562:587	Here, a mussel-inspired strategy was adopted to prepare a multifunctional hydrogel created by H2O2/CuSO4-induced rapid polydopamine (PDA) deposition on carboxymethyl chitosan (CMC)/sodium alginate (Alg) based hydrogel, termed as CAC/PDA/Cu(H2O2).					
36427613	6	71	theme	H2O2	1182:1185	arg1	hydrogel					1188:1195	CAC/PDA/Cu(H2O2) hydrogel	1171:1195	CAC/PDA/Cu(H2O2) hydrogel	1171:1195	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	0	72	theme	promising	79:87	arg1	dressings					89:97	promising dressings	79:97	promising dressings for eliminating biofilm and multidrug-resistant bacteria	79:154	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	6	73	theme	CAC/PDA/Cu	1171:1180	arg1	hydrogel					1188:1195	CAC/PDA/Cu(H2O2) hydrogel	1171:1195	CAC/PDA/Cu(H2O2) hydrogel	1171:1195	Significantly, CAC/PDA/Cu(H2O2) hydrogel illustrates excellent therapeutic effects in Methicillin-resistant Staphylococcus aureus (MRSA) induced-rat infection models, which can efficiently eliminate MRSA, dramatically reduce inflammatory expression, promote angiogenesis, and ultimately shorten the wound healing time.					
36427613	7	74	dep	days	1542:1545	arg1	11					1567:1568	11	1567:1568	11	1567:1568	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	7	74	dep	days	1542:1545	arg1	14					1592:1593	14	1592:1593	14	1592:1593	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	7	74	dep	days	1542:1545	arg1	%					1609:1609	97.86 ± 0.66 %	1596:1609	97.86 ± 0.66 %	1596:1609	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	7	74	dep	days	1542:1545	arg1	%					1563:1563	80.63 ± 2.44 %	1550:1563	80.63 ± 2.44 %	1550:1563	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	7	74	dep	days	1542:1545	arg1	%					1584:1584	92.45 ± 2.26 %	1571:1584	92.45 ± 2.26 %	1571:1584	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	7	74	dep	days	1542:1545	arg1	7					1547:1547	7	1547:1547	7	1547:1547	CAC/PDA/Cu(H2O2) hydrogel exhibited the best wound healing rate on days 7 (80.63 ± 2.44 %), 11 (92.45 ± 2.26 %), and 14 (97.86 ± 0.66 %).					
36427613	0	75	theme	chitosan/sodium	14:28	arg1	hydrogels					39:47	Carboxymethyl chitosan/sodium alginate hydrogels	0:47	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria	0:154	Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.					
36427613	1	76	theme	wound	299:303	arg1	treatment					305:313	wound treatment	299:313	wound treatment	299:313	Microorganisms induced wound infection and the accompanying excessive inflammatory response is the daunting problems in wound treatment.					
35045344	7	0	theme	blue	1171:1174	arg1	methylene					1161:1169	methylene blue	1161:1174	methylene blue	1161:1174	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	1	located	found	1192:1196	arg2	52.3 mg/g					1204:1212	52.3 mg/g	1204:1212	52.3 mg/g	1204:1212	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	1	located	found	1192:1196	arg2	capacities					1147:1156	The maximum adsorption capacities	1124:1156	The maximum adsorption capacities of methylene blue	1124:1174	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	1	located	found	1192:1196	arg1	20 °C					1180:1184	20 °C	1180:1184	20 °C	1180:1184	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	0	2	theme	methylene	163:171	arg1	dye					178:180	methylene blue dye	163:180	methylene blue dye	163:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	8	3	theme	order	1386:1390	arg1	kinetics					1392:1399	pseudo second order kinetics	1372:1399	pseudo second order kinetics	1372:1399	The adsorption process followed Freundlich isotherm and pseudo second order kinetics.					
35045344	1	4	theme	simple	230:235	arg1	strategy					237:244	a simple strategy	228:244	a simple strategy to realize new materials with added benefits	228:289	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	0	5	theme	porphyrinto	78:88	arg1	II					96:97	II	96:97	II	96:97	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	5	theme	porphyrinto	78:88	arg1	zinc					91:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc	34:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II)	34:98	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	2	6	theme	2,4,6-trimethylphenyl	321:341	arg1	zinc					357:360	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	307:364	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads	307:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	6	7	theme	calcium	959:965	arg1	ions					967:970	calcium ions	959:970	calcium ions	959:970	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	2	8	theme	dye	484:486	arg1	removal					462:468	the removal	458:468	the removal of a cationic dye from aqueous solution	458:508	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	7	9	theme	sodium	1279:1284	arg1	beads					1295:1299	plain sodium alginate beads	1273:1299	plain sodium alginate beads	1273:1299	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	0	10	theme	dye	178:180	arg1	adsorption					149:158	improved adsorption	140:158	improved adsorption of methylene blue dye	140:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	7	11	theme	alginate	1286:1293	arg1	beads					1295:1299	plain sodium alginate beads	1273:1299	plain sodium alginate beads	1273:1299	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	4	12	theme	porphyrinto	721:731	arg1	complex					743:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	6	13	theme	small	1091:1095	arg1	decrease					1097:1104	a small decrease	1089:1104	a small decrease of residual mass	1089:1121	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	0	14	theme	zinc	91:94	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	14	theme	zinc	91:94	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	15	theme	blue	173:176	arg1	dye					178:180	methylene blue dye	163:180	methylene blue dye	163:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	6	16	theme	biopolymer	943:952	arg1	groups					929:934	hydroxyl and carboxylate groups	904:934	groups	929:934	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	16	theme	biopolymer	943:952	arg1	biopolymer					943:952	the biopolymer	939:952	the biopolymer	939:952	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	7	17	theme	adsorption	1136:1145	arg1	52.3 mg/g					1204:1212	52.3 mg/g	1204:1212	52.3 mg/g	1204:1212	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	17	theme	adsorption	1136:1145	arg1	capacities					1147:1156	The maximum adsorption capacities	1124:1156	The maximum adsorption capacities of methylene blue	1124:1174	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	5	18	theme	composite	867:875	arg1	beads					877:881	spherical and smooth composite beads	846:881	spherical and smooth composite beads	846:881	The morphological micrographs showed spherical and smooth composite beads.					
35045344	4	19	theme	H-bonding	792:800	arg1	mode					803:806	non-covalent interaction (H-bonding) mode	766:806	non-covalent interaction (H-bonding) mode	766:806	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	2	20	theme	alginate	383:390	arg1	beads					396:400	sodium alginate gel beads	376:400	sodium alginate gel beads	376:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	4	21	theme	zinc	734:737	arg1	complex					743:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	6	22	theme	2,4,6-trimethylphenyl	1011:1031	arg1	zinc					1047:1050	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	5	23	theme	smooth	860:865	arg1	beads					877:881	spherical and smooth composite beads	846:881	spherical and smooth composite beads	846:881	The morphological micrographs showed spherical and smooth composite beads.					
35045344	7	24	theme	composite	1248:1256	arg1	beads					1258:1262	sodium alginate composite beads	1232:1262	sodium alginate composite beads (3%)	1232:1267	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	24	theme	composite	1248:1256	arg1	%					1266:1266	3%	1265:1266	3%	1265:1266	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	6	25	theme	mass	1118:1121	arg1	decrease					1097:1104	a small decrease	1089:1104	a small decrease of residual mass	1089:1121	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	26	theme	zinc	1047:1050	arg1	crosslinking					888:899	The crosslinking	884:899	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions	884:970	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	26	theme	zinc	1047:1050	arg1	incorporation					980:992	the incorporation	976:992	the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix	976:1075	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	27	theme	carboxylate	917:927	arg1	groups					929:934	hydroxyl and carboxylate groups	904:934	groups	929:934	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	27	theme	carboxylate	917:927	arg1	biopolymer					943:952	the biopolymer	939:952	the biopolymer	939:952	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	4	28	theme	meso-tetrakis	684:696	arg1	complex					743:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	9	29	theme	thermodynamic	1406:1418	arg1	study					1420:1424	The thermodynamic study	1402:1424	The thermodynamic study	1402:1424	The thermodynamic study displayed an exothermic and non-spontaneous process.					
35045344	5	30	theme	morphological	813:825	arg1	micrographs					827:837	The morphological micrographs	809:837	The morphological micrographs	809:837	The morphological micrographs showed spherical and smooth composite beads.					
35045344	2	31	theme	aqueous	493:499	arg1	solution					501:508	aqueous solution	493:508	aqueous solution	493:508	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	1	32	theme	new	257:259	arg1	materials					261:269	new materials	257:269	new materials with added benefits	257:289	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	6	33	with	crosslinking	888:899	arg1	ions					967:970	calcium ions	959:970	calcium ions	959:970	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	34	theme	residual	1109:1116	arg1	mass					1118:1121	residual mass	1109:1121	residual mass	1109:1121	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	35	theme	porphyrinto	1034:1044	arg1	zinc					1047:1050	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	0	36	theme	sodium	110:115	arg1	beads					130:134	sodium alginate gel beads	110:134	sodium alginate gel beads for improved adsorption of methylene blue dye	110:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	1	37	with	materials	261:269	arg1	benefits					282:289	added benefits	276:289	added benefits	276:289	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	4	38	theme	2,4,6-trimethylphenyl	698:718	arg1	complex					743:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex	684:749	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	2	39	theme	gel	392:394	arg1	beads					396:400	sodium alginate gel beads	376:400	sodium alginate gel beads	376:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	7	40	theme	sodium	1232:1237	arg1	beads					1258:1262	sodium alginate composite beads	1232:1262	sodium alginate composite beads (3%)	1232:1267	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	40	theme	sodium	1232:1237	arg1	%					1266:1266	3%	1265:1266	3%	1265:1266	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	6	41	theme	groups	929:934	arg1	crosslinking					888:899	The crosslinking	884:899	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions	884:970	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	41	theme	groups	929:934	arg1	incorporation					980:992	the incorporation	976:992	the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix	976:1075	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	42	with	incorporation	980:992	arg1	ions					967:970	calcium ions	959:970	calcium ions	959:970	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	3	43	theme	chemical	515:522	arg1	structure					524:532	The chemical structure	511:532	The chemical structure of the prepared composite beads	511:564	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	1	44	theme	Chemical	183:190	arg1	modification					192:203	Chemical modification	183:203	Chemical modification of a biopolymer	183:219	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	0	45	theme	new	36:38	arg1	II					96:97	II	96:97	II	96:97	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	45	theme	new	36:38	arg1	zinc					91:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc	34:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II)	34:98	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	1	46	theme	added	276:280	arg1	benefits					282:289	added benefits	276:289	added benefits	276:289	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	0	47	theme	gel	126:128	arg1	beads					130:134	sodium alginate gel beads	110:134	sodium alginate gel beads for improved adsorption of methylene blue dye	110:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	3	48	theme	XRD	595:597	arg1	techniques					611:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	3	49	theme	composite	550:558	arg1	beads					560:564	the prepared composite beads	537:564	the prepared composite beads	537:564	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	2	50	theme	sodium	376:381	arg1	beads					396:400	sodium alginate gel beads	376:400	sodium alginate gel beads	376:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	8	51	theme	adsorption	1320:1329	arg1	process					1331:1337	The adsorption process	1316:1337	The adsorption process	1316:1337	The adsorption process followed Freundlich isotherm and pseudo second order kinetics.					
35045344	0	52	theme	alginate	117:124	arg1	beads					130:134	sodium alginate gel beads	110:134	sodium alginate gel beads for improved adsorption of methylene blue dye	110:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	3	53	theme	beads	560:564	arg1	structure					524:532	The chemical structure	511:532	The chemical structure of the prepared composite beads	511:564	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	6	54	theme	meso-tetrakis	997:1009	arg1	zinc					1047:1050	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	997:1054	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	55	theme	hydroxyl	904:911	arg1	groups					929:934	hydroxyl and carboxylate groups	904:934	groups	929:934	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	6	55	theme	hydroxyl	904:911	arg1	biopolymer					943:952	the biopolymer	939:952	the biopolymer	939:952	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	4	56	theme	non-covalent	766:777	arg1	mode					803:806	non-covalent interaction (H-bonding) mode	766:806	non-covalent interaction (H-bonding) mode	766:806	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	3	57	theme	SEM	590:592	arg1	techniques					611:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	4	58	theme	interaction	779:789	arg1	mode					803:806	non-covalent interaction (H-bonding) mode	766:806	non-covalent interaction (H-bonding) mode	766:806	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	6	59	theme	alginate	1061:1068	arg1	matrix					1070:1075	alginate matrix	1061:1075	alginate matrix	1061:1075	The crosslinking of hydroxyl and carboxylate groups of the biopolymer with calcium ions and the incorporation of meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) into alginate matrix resulted in a small decrease of residual mass.					
35045344	4	60	theme	sodium	658:663	arg1	beads					674:678	the sodium alginate beads	654:678	the sodium alginate beads	654:678	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	0	61	theme	meso-tetrakis	40:52	arg1	II					96:97	II	96:97	II	96:97	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	61	theme	meso-tetrakis	40:52	arg1	zinc					91:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc	34:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II)	34:98	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	9	62	theme	non-spontaneous	1454:1468	arg1	process					1470:1476	an exothermic and non-spontaneous process	1436:1476	an exothermic and non-spontaneous process	1436:1476	The thermodynamic study displayed an exothermic and non-spontaneous process.					
35045344	2	63	used	used	449:452	arg2	zinc					357:360	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	307:364	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads	307:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	3	64	theme	prepared	541:548	arg1	beads					560:564	the prepared composite beads	537:564	the prepared composite beads	537:564	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	7	65	theme	methylene	1161:1169	arg1	52.3 mg/g					1204:1212	52.3 mg/g	1204:1212	52.3 mg/g	1204:1212	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	65	theme	methylene	1161:1169	arg1	capacities					1147:1156	The maximum adsorption capacities	1124:1156	The maximum adsorption capacities of methylene blue	1124:1174	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	2	66	theme	meso-tetrakis	307:319	arg1	zinc					357:360	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	307:364	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads	307:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	8	67	theme	pseudo	1372:1377	arg1	kinetics					1392:1399	pseudo second order kinetics	1372:1399	pseudo second order kinetics	1372:1399	The adsorption process followed Freundlich isotherm and pseudo second order kinetics.					
35045344	8	68	theme	Freundlich	1348:1357	arg1	isotherm					1359:1366	Freundlich isotherm	1348:1366	Freundlich isotherm	1348:1366	The adsorption process followed Freundlich isotherm and pseudo second order kinetics.					
35045344	7	69	theme	plain	1273:1277	arg1	beads					1295:1299	plain sodium alginate beads	1273:1299	plain sodium alginate beads	1273:1299	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	4	70	theme	Analytical	623:632	arg1	data					634:637	Analytical data	623:637	Analytical data	623:637	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	9	71	theme	exothermic	1439:1448	arg1	process					1470:1476	an exothermic and non-spontaneous process	1436:1476	an exothermic and non-spontaneous process	1436:1476	The thermodynamic study displayed an exothermic and non-spontaneous process.					
35045344	0	72	theme	improved	140:147	arg1	adsorption					149:158	improved adsorption	140:158	improved adsorption of methylene blue dye	140:180	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	8	73	theme	second	1379:1384	arg1	kinetics					1392:1399	pseudo second order kinetics	1372:1399	pseudo second order kinetics	1372:1399	The adsorption process followed Freundlich isotherm and pseudo second order kinetics.					
35045344	3	74	theme	FT-IR	583:587	arg1	techniques					611:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	4	75	theme	alginate	665:672	arg1	beads					674:678	the sodium alginate beads	654:678	the sodium alginate beads	654:678	Analytical data suggested that the sodium alginate beads and meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) complex interacted via non-covalent interaction (H-bonding) mode.					
35045344	1	76	theme	biopolymer	210:219	arg1	modification					192:203	Chemical modification	183:203	Chemical modification of a biopolymer	183:219	Chemical modification of a biopolymer offers a simple strategy to realize new materials with added benefits.					
35045344	3	77	theme	TGA/DTG	603:609	arg1	techniques					611:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	FT-IR, SEM, XRD and TGA/DTG techniques	583:620	The chemical structure of the prepared composite beads was confirmed by FT-IR, SEM, XRD and TGA/DTG techniques.					
35045344	7	78	theme	alginate	1239:1246	arg1	beads					1258:1262	sodium alginate composite beads	1232:1262	sodium alginate composite beads (3%)	1232:1267	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	78	theme	alginate	1239:1246	arg1	%					1266:1266	3%	1265:1266	3%	1265:1266	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	5	79	theme	spherical	846:854	arg1	beads					877:881	spherical and smooth composite beads	846:881	spherical and smooth composite beads	846:881	The morphological micrographs showed spherical and smooth composite beads.					
35045344	0	80	theme	2,4,6-trimethylphenyl	55:75	arg1	II					96:97	II	96:97	II	96:97	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	0	80	theme	2,4,6-trimethylphenyl	55:75	arg1	zinc					91:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc	34:94	a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II)	34:98	Synthesis and characterization of a new meso-tetrakis (2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads for improved adsorption of methylene blue dye.					
35045344	2	81	from	solution	501:508	arg1	removal					462:468	the removal	458:468	the removal of a cationic dye from aqueous solution	458:508	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	2	82	theme	porphyrinto	344:354	arg1	zinc					357:360	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II)	307:364	meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads	307:400	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
35045344	7	83	theme	maximum	1128:1134	arg1	52.3 mg/g					1204:1212	52.3 mg/g	1204:1212	52.3 mg/g	1204:1212	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	7	83	theme	maximum	1128:1134	arg1	capacities					1147:1156	The maximum adsorption capacities	1124:1156	The maximum adsorption capacities of methylene blue	1124:1174	The maximum adsorption capacities of methylene blue, at 20 °C, were found to be 52.3 mg/g and 34.8 mg/g for sodium alginate composite beads (3%) and plain sodium alginate beads, respectively.					
35045344	2	84	theme	cationic	475:482	arg1	dye					484:486	a cationic dye	473:486	a cationic dye	473:486	In this paper, meso-tetrakis(2,4,6-trimethylphenyl) porphyrinto) zinc(II) supported sodium alginate gel beads were successfully prepared, characterized, and used for the removal of a cationic dye from aqueous solution.					
37059554	0	0	theme	hydrogel	99:106	arg1	fabrication					43:53	the fabrication	39:53	the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors	39:125	Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors.					
37059554	7	1	theme	human	1347:1351	arg1	beings					1353:1358	human beings	1347:1358	human beings	1347:1358	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	4	2	theme	xylan-based	674:684	arg1	hydrogels					686:694	corresponding xylan-based hydrogels	660:694	corresponding xylan-based hydrogels	660:694	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	0	3	theme	xylan-based	87:97	arg1	hydrogel					99:106	highly stretchable and tough xylan-based hydrogel	58:106	highly stretchable and tough xylan-based hydrogel	58:106	Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors.					
37059554	7	4	theme	synthesized	1224:1234	arg1	able					1263:1266	able	1263:1266	able	1263:1266	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	4	theme	synthesized	1224:1234	arg1	hydrogels					1248:1256	the synthesized xylan-based hydrogels	1220:1256	the synthesized xylan-based hydrogels	1220:1256	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	4	theme	synthesized	1224:1234	arg1	sensor					1312:1317	a reliable and sensitive strain sensor	1280:1317	a reliable and sensitive strain sensor	1280:1317	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	4	5	theme	corresponding	660:672	arg1	hydrogels					686:694	corresponding xylan-based hydrogels	660:694	corresponding xylan-based hydrogels	660:694	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	0	6	theme	strain	112:117	arg1	sensors					119:125	strain sensors	112:125	strain sensors	112:125	Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors.					
37059554	4	7	theme	compositions	580:591	arg1	effect					560:565	The effect	556:565	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels	556:694	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	5	8	theme	different	784:792	arg1	components					794:803	different components	784:803	different components to dissipate energies	784:825	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	3	9	theme	novel	445:449	arg1	stretchable					451:461	a novel stretchable	443:461	a novel stretchable	443:461	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	5	10	theme	derivative	871:880	arg1	orientation					850:860	the strain-induced orientation	831:860	the strain-induced orientation of rosin derivative during the stretching	831:902	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	5	10	theme	derivative	871:880	arg1	components					794:803	different components	784:803	different components to dissipate energies	784:825	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	7	11	theme	beings	1353:1358	arg1	movements					1334:1342	the movements	1330:1342	the movements of human beings	1330:1358	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	12	theme	reliable	1282:1289	arg1	hydrogels					1248:1256	the synthesized xylan-based hydrogels	1220:1256	the synthesized xylan-based hydrogels	1220:1256	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	12	theme	reliable	1282:1289	arg1	sensor					1312:1317	a reliable and sensitive strain sensor	1280:1317	a reliable and sensitive strain sensor	1280:1317	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	8	13	theme	natural	1485:1491	arg1	feature					1493:1499	the natural feature	1481:1499	the natural feature of bio-based resources	1481:1522	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	2	14	theme	renewable	382:390	arg1	xylan					392:396	renewable xylan	382:396	renewable xylan	382:396	However, it still remains a great challenge to simultaneously own satisfactory stretchability and toughness, particularly when incorporating renewable xylan to offer sustainability.					
37059554	8	15	theme	conductive	1427:1436	arg1	hydrogel					1450:1457	conductive xylan-based hydrogel	1427:1457	conductive xylan-based hydrogel	1427:1457	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	4	16	from	effect	560:565	arg1	properties					611:620	the mechanical properties	596:620	the mechanical properties	596:620	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	4	16	from	effect	560:565	arg1	properties					646:655	the physicochemical properties	626:655	the physicochemical properties	626:655	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	5	17	theme	hydrogels	972:980	arg1	strain					935:940	strain	935:940	strain	935:940	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	5	17	theme	hydrogels	972:980	arg1	toughness					947:955	toughness	947:955	toughness	947:955	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	5	17	theme	hydrogels	972:980	arg1	strength					925:932	the highest tensile strength	905:932	the highest tensile strength	905:932	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	8	18	theme	bio-based	1504:1512	arg1	resources					1514:1522	bio-based resources	1504:1522	bio-based resources	1504:1522	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	1	19	theme	various	219:225	arg1	applications					227:238	various applications	219:238	various applications	219:238	Stretchable and tough polysaccharide-based functional hydrogels have gained popularity for various applications.					
37059554	4	20	theme	hydrogels	686:694	arg1	properties					611:620	the mechanical properties	596:620	the mechanical properties	596:620	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	4	20	theme	hydrogels	686:694	arg1	properties					646:655	the physicochemical properties	626:655	the physicochemical properties	626:655	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	5	21	theme	tensile	917:923	arg1	strength					925:932	the highest tensile strength	905:932	the highest tensile strength	905:932	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	2	22	theme	satisfactory	307:318	arg1	stretchability					320:333	own satisfactory stretchability	303:333	own satisfactory stretchability	303:333	However, it still remains a great challenge to simultaneously own satisfactory stretchability and toughness, particularly when incorporating renewable xylan to offer sustainability.					
37059554	5	23	theme	highest	909:915	arg1	strength					925:932	the highest tensile strength	905:932	the highest tensile strength	905:932	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	5	24	theme	multiple	743:750	arg1	interactions					765:776	the multiple non-covalent interactions	739:776	the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching	739:902	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	3	25	theme	conductive	485:494	arg1	hydrogel					496:503	tough xylan-based conductive hydrogel	467:503	tough xylan-based conductive hydrogel	467:503	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	0	26	theme	Strain-induced	0:13	arg1	orientation					15:25	Strain-induced orientation	0:25	Strain-induced orientation	0:25	Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors.					
37059554	4	27	theme	physicochemical	630:644	arg1	properties					646:655	the physicochemical properties	626:655	the physicochemical properties	626:655	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	5	28	theme	non-covalent	752:763	arg1	interactions					765:776	the multiple non-covalent interactions	739:776	the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching	739:902	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	7	29	theme	xylan-based	1236:1246	arg1	able					1263:1266	able	1263:1266	able	1263:1266	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	29	theme	xylan-based	1236:1246	arg1	hydrogels					1248:1256	the synthesized xylan-based hydrogels	1220:1256	the synthesized xylan-based hydrogels	1220:1256	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	29	theme	xylan-based	1236:1246	arg1	sensor					1312:1317	a reliable and sensitive strain sensor	1280:1317	a reliable and sensitive strain sensor	1280:1317	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	8	30	theme	new	1381:1383	arg1	insights					1385:1392	new insights	1381:1392	new insights	1381:1392	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	7	31	theme	sensitive	1295:1303	arg1	hydrogels					1248:1256	the synthesized xylan-based hydrogels	1220:1256	the synthesized xylan-based hydrogels	1220:1256	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	31	theme	sensitive	1295:1303	arg1	sensor					1312:1317	a reliable and sensitive strain sensor	1280:1317	a reliable and sensitive strain sensor	1280:1317	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	5	32	theme	xylan-based	960:970	arg1	hydrogels					972:980	xylan-based hydrogels	960:980	xylan-based hydrogels	960:980	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	7	33	theme	strain	1305:1310	arg1	hydrogels					1248:1256	the synthesized xylan-based hydrogels	1220:1256	the synthesized xylan-based hydrogels	1220:1256	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	7	33	theme	strain	1305:1310	arg1	sensor					1312:1317	a reliable and sensitive strain sensor	1280:1317	a reliable and sensitive strain sensor	1280:1317	Finally, the synthesized xylan-based hydrogels were able to serve as a reliable and sensitive strain sensor to monitor the movements of human beings.					
37059554	6	34	theme	conductive	1094:1103	arg1	MXene					1081:1085	MXene	1081:1085	MXene	1081:1085	Furthermore, by incorporating MXene as the conductive fillers, the strength and toughness of hydrogels were further enhanced to 0.51 MPa and 5.95 ± 1.19 MJ/m3.					
37059554	6	34	theme	conductive	1094:1103	arg1	fillers					1105:1111	the conductive fillers	1090:1111	the conductive fillers	1090:1111	Furthermore, by incorporating MXene as the conductive fillers, the strength and toughness of hydrogels were further enhanced to 0.51 MPa and 5.95 ± 1.19 MJ/m3.					
37059554	5	35	theme	strain-induced	835:848	arg1	orientation					850:860	the strain-induced orientation	831:860	the strain-induced orientation of rosin derivative during the stretching	831:902	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	3	36	theme	rosin	538:542	arg1	derivative					544:553	rosin derivative	538:553	rosin derivative	538:553	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	3	37	theme	tough	467:471	arg1	hydrogel					496:503	tough xylan-based conductive hydrogel	467:503	tough xylan-based conductive hydrogel	467:503	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	2	38	theme	great	269:273	arg1	challenge					275:283	a great challenge	267:283	a great challenge to simultaneously own satisfactory stretchability and toughness, particularly when incorporating renewable xylan to offer sustainability	267:420	However, it still remains a great challenge to simultaneously own satisfactory stretchability and toughness, particularly when incorporating renewable xylan to offer sustainability.					
37059554	3	39	theme	natural	519:525	arg1	feature					527:533	the natural feature	515:533	the natural feature of rosin derivative	515:553	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	3	40	theme	xylan-based	473:483	arg1	hydrogel					496:503	tough xylan-based conductive hydrogel	467:503	tough xylan-based conductive hydrogel	467:503	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	4	41	theme	mechanical	600:609	arg1	properties					611:620	the mechanical properties	596:620	the mechanical properties	596:620	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
37059554	5	42	dep	components	794:803	arg1	dissipate					808:816	dissipate	808:816	to dissipate energies	805:825	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	8	43	theme	xylan-based	1438:1448	arg1	hydrogel					1450:1457	conductive xylan-based hydrogel	1427:1457	conductive xylan-based hydrogel	1427:1457	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	0	44	theme	stretchable	65:75	arg1	hydrogel					99:106	highly stretchable and tough xylan-based hydrogel	58:106	highly stretchable and tough xylan-based hydrogel	58:106	Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors.					
37059554	5	45	theme	rosin	865:869	arg1	derivative					871:880	rosin derivative	865:880	rosin derivative	865:880	Owing to the multiple non-covalent interactions among different components to dissipate energies and the strain-induced orientation of rosin derivative during the stretching, the highest tensile strength, strain, and toughness of xylan-based hydrogels could reach 0.34 MPa, 2098.4 %, and 3.79 ± 0.95 MJ/m3, respectively.					
37059554	8	46	theme	resources	1514:1522	arg1	feature					1493:1499	the natural feature	1481:1499	the natural feature of bio-based resources	1481:1522	This study provides new insights to develop stretchable and tough conductive xylan-based hydrogel, especially utilizing the natural feature of bio-based resources.					
37059554	1	47	theme	Stretchable	128:138	arg1	hydrogels					182:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels have gained popularity for various applications.					
37059554	6	48	dep	strength	1118:1125	arg1	the					1114:1116	the	1114:1116	the	1114:1116	Furthermore, by incorporating MXene as the conductive fillers, the strength and toughness of hydrogels were further enhanced to 0.51 MPa and 5.95 ± 1.19 MJ/m3.					
37059554	2	49	theme	own	303:305	arg1	stretchability					320:333	own satisfactory stretchability	303:333	own satisfactory stretchability	303:333	However, it still remains a great challenge to simultaneously own satisfactory stretchability and toughness, particularly when incorporating renewable xylan to offer sustainability.					
37059554	1	50	theme	tough	144:148	arg1	hydrogels					182:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels have gained popularity for various applications.					
37059554	1	51	theme	polysaccharide-based	150:169	arg1	hydrogels					182:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels have gained popularity for various applications.					
37059554	3	52	theme	derivative	544:553	arg1	feature					527:533	the natural feature	515:533	the natural feature of rosin derivative	515:553	Herein, we describe a novel stretchable and tough xylan-based conductive hydrogel utilizing the natural feature of rosin derivative.					
37059554	1	53	theme	functional	171:180	arg1	hydrogels					182:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels	128:190	Stretchable and tough polysaccharide-based functional hydrogels have gained popularity for various applications.					
37059554	6	54	theme	hydrogels	1144:1152	arg1	toughness					1131:1139	toughness	1131:1139	toughness	1131:1139	Furthermore, by incorporating MXene as the conductive fillers, the strength and toughness of hydrogels were further enhanced to 0.51 MPa and 5.95 ± 1.19 MJ/m3.					
37059554	6	54	theme	hydrogels	1144:1152	arg1	strength					1118:1125	strength	1118:1125	strength	1118:1125	Furthermore, by incorporating MXene as the conductive fillers, the strength and toughness of hydrogels were further enhanced to 0.51 MPa and 5.95 ± 1.19 MJ/m3.					
37059554	4	55	theme	different	570:578	arg1	compositions					580:591	different compositions	570:591	different compositions	570:591	The effect of different compositions on the mechanical properties and the physicochemical properties of corresponding xylan-based hydrogels were systematically investigated.					
35725162	6	0	theme	output	1089:1094	arg1	power					1096:1100	an output power	1086:1100	an output power of approximately 4.9 W/m2 in osmotic energy harvesting	1086:1155	This system could deliver an output power of approximately 4.9 W/m2 in osmotic energy harvesting.					
35725162	3	1	theme	osmotic	745:751	arg1	conversion					760:769	osmotic energy conversion	745:769	osmotic energy conversion	745:769	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	6	2	from	power	1096:1100	arg1	harvesting					1146:1155	osmotic energy harvesting	1131:1155	osmotic energy harvesting	1131:1155	This system could deliver an output power of approximately 4.9 W/m2 in osmotic energy harvesting.					
35725162	1	3	theme	seek	188:191	arg1	environment					212:222	seek comfortable living environment	188:222	seek comfortable living environment	188:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	4	theme	-modified	572:580	arg1	nanochannels					590:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	3	5	theme	energy	753:758	arg1	conversion					760:769	osmotic energy conversion	745:769	osmotic energy conversion	745:769	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	7	6	theme	transport	1211:1219	arg1	principle					1221:1229	a simple photothermal-gating ion transport principle	1178:1229	a simple photothermal-gating ion transport principle in laminar RC membrane	1178:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	4	7	theme	inducing	811:818	arg1	changes					832:838	inducing temperature changes	811:838	inducing temperature changes	811:838	Nanochannels are activated upon photo, inducing temperature changes result in PLL molecule structure shifted from α-helix to β-sheet.					
35725162	1	8	theme	photo	298:302	arg1	gating					304:309	photo gating	298:309	photo gating	298:309	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	5	9	from	temperatures	961:972	arg1	ratio					942:946	the rectification ratio	924:946	the rectification ratio at different temperatures	924:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	5	9	from	temperatures	961:972	arg1	difference					910:919	The difference	906:919	The difference in the rectification ratio at different temperatures	906:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	7	10	theme	photothermal-gating	1187:1205	arg1	principle					1221:1229	a simple photothermal-gating ion transport principle	1178:1229	a simple photothermal-gating ion transport principle in laminar RC membrane	1178:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	6	11	theme	energy	1139:1144	arg1	harvesting					1146:1155	osmotic energy harvesting	1131:1155	osmotic energy harvesting	1131:1155	This system could deliver an output power of approximately 4.9 W/m2 in osmotic energy harvesting.					
35725162	4	12	theme	PLL	850:852	arg1	structure					863:871	PLL molecule structure	850:871	PLL molecule structure shifted from α-helix to β-sheet	850:903	Nanochannels are activated upon photo, inducing temperature changes result in PLL molecule structure shifted from α-helix to β-sheet.					
35725162	4	13	theme	molecule	854:861	arg1	structure					863:871	PLL molecule structure	850:871	PLL molecule structure shifted from α-helix to β-sheet	850:903	Nanochannels are activated upon photo, inducing temperature changes result in PLL molecule structure shifted from α-helix to β-sheet.					
35725162	1	14	theme	comfortable	193:203	arg1	environment					212:222	seek comfortable living environment	188:222	seek comfortable living environment	188:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	7	15	theme	RC	1242:1243	arg1	membrane					1245:1252	laminar RC membrane	1234:1252	laminar RC membrane	1234:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	7	16	theme	ion	1207:1209	arg1	principle					1221:1229	a simple photothermal-gating ion transport principle	1178:1229	a simple photothermal-gating ion transport principle in laminar RC membrane	1178:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	1	17	theme	living	205:210	arg1	environment					212:222	seek comfortable living environment	188:222	seek comfortable living environment	188:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	0	18	theme	regenerated	8:18	arg1	membrane					30:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	0	19	theme	Laminar	0:6	arg1	membrane					30:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	3	20	theme	ion	732:734	arg1	flux					736:739	ion flux	732:739	ion flux	732:739	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	1	21	from	sensors	145:151	arg1	system					178:183	the mammalian sensory system	156:183	the mammalian sensory system to seek comfortable living environment	156:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	22	theme	cellulose	429:437	arg1	membrane					444:451	laminar regenerated cellulose (RC) membrane	409:451	laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	409:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	23	link	superbase-derived	518:534	arg1	liquid					542:547	liquid	542:547	liquid	542:547	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	24	theme	terephthalate	616:628	arg1	substrate					636:644	polyethylene terephthalate (PET) substrate	603:644	polyethylene terephthalate (PET) substrate	603:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	1	25	theme	acute	127:131	arg1	sensors					145:151	acute temperature sensors	127:151	acute temperature sensors in the mammalian sensory system to seek comfortable living environment	127:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	0	26	theme	cellulose	20:28	arg1	membrane					30:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane	0:37	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	1	27	theme	photothermal	319:330	arg1	membrane					356:363	photothermal controlled nanochannels membrane	319:363	photothermal controlled nanochannels membrane	319:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	28	theme	polyethylene	603:614	arg1	PET					631:633	PET	631:633	PET	631:633	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	28	theme	polyethylene	603:614	arg1	terephthalate					616:628	polyethylene terephthalate	603:628	polyethylene terephthalate (PET) substrate	603:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	1	29	theme	temperature	133:143	arg1	sensors					145:151	acute temperature sensors	127:151	acute temperature sensors in the mammalian sensory system to seek comfortable living environment	127:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	30	theme	regenerated	417:427	arg1	membrane					444:451	laminar regenerated cellulose (RC) membrane	409:451	laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	409:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	1	31	theme	controlled	332:341	arg1	membrane					356:363	photothermal controlled nanochannels membrane	319:363	photothermal controlled nanochannels membrane	319:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	6	32	theme	osmotic	1131:1137	arg1	harvesting					1146:1155	osmotic energy harvesting	1131:1155	osmotic energy harvesting	1131:1155	This system could deliver an output power of approximately 4.9 W/m2 in osmotic energy harvesting.					
35725162	5	33	theme	different	951:959	arg1	temperatures					961:972	different temperatures	951:972	different temperatures	951:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	1	34	theme	temperature	238:248	arg1	nanochannels					258:269	temperature sensing nanochannels	238:269	temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane	238:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	5	35	theme	rectification	928:940	arg1	ratio					942:946	the rectification ratio	924:946	the rectification ratio at different temperatures	924:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	1	36	theme	nanochannels	343:354	arg1	membrane					356:363	photothermal controlled nanochannels membrane	319:363	photothermal controlled nanochannels membrane	319:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	37	theme	conical	582:588	arg1	nanochannels					590:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	1	38	theme	sensing	250:256	arg1	nanochannels					258:269	temperature sensing nanochannels	238:269	temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane	238:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	0	39	theme	photothermal-gating	69:87	arg1	harvesting					103:112	high-performance photothermal-gating osmotic power harvesting	52:112	high-performance photothermal-gating osmotic power harvesting	52:112	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	7	40	from	principle	1221:1229	arg1	membrane					1245:1252	laminar RC membrane	1234:1252	laminar RC membrane	1234:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	2	41	dep	liquid	542:547	arg1	substrate					636:644	polyethylene terephthalate (PET) substrate	603:644	polyethylene terephthalate (PET) substrate	603:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	3	42	theme	gating	702:707	arg1	modifiers					709:717	gating modifiers	702:717	gating modifiers	702:717	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	3	42	theme	gating	702:707	arg1	nanoparticles					653:665	Fe3O4 nanoparticles	647:665	Fe3O4 nanoparticles	647:665	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	5	43	theme	photothermal-dependent	993:1014	arg1	opening					1016:1022	photothermal-dependent opening	993:1022	photothermal-dependent opening	993:1022	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	0	44	theme	high-performance	52:67	arg1	harvesting					103:112	high-performance photothermal-gating osmotic power harvesting	52:112	high-performance photothermal-gating osmotic power harvesting	52:112	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	3	45	theme	Fe3O4	647:651	arg1	nanoparticles					653:665	Fe3O4 nanoparticles	647:665	Fe3O4 nanoparticles	647:665	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	3	45	theme	Fe3O4	647:651	arg1	modifiers					709:717	gating modifiers	702:717	gating modifiers	702:717	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	7	46	theme	laminar	1234:1240	arg1	membrane					1245:1252	laminar RC membrane	1234:1252	laminar RC membrane	1234:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	2	47	theme	laminar	409:415	arg1	membrane					444:451	laminar regenerated cellulose (RC) membrane	409:451	laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	409:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	3	48	theme	RC	687:688	arg1	membrane					690:697	RC membrane	687:697	RC membrane	687:697	Fe3O4 nanoparticles are introduced into RC membrane as gating modifiers, controlling ion flux and osmotic energy conversion.					
35725162	5	49	from	difference	910:919	arg1	ratio					942:946	the rectification ratio	924:946	the rectification ratio at different temperatures	924:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	5	49	from	difference	910:919	arg1	temperatures					961:972	different temperatures	951:972	different temperatures	951:972	The difference in the rectification ratio at different temperatures is associated with photothermal-dependent opening and closing, its maximum is 116.76.					
35725162	4	50	theme	temperature	820:830	arg1	changes					832:838	inducing temperature changes	811:838	inducing temperature changes	811:838	Nanochannels are activated upon photo, inducing temperature changes result in PLL molecule structure shifted from α-helix to β-sheet.					
35725162	6	51	theme	4.9 W/m2	1119:1126	arg1	power					1096:1100	an output power	1086:1100	an output power of approximately 4.9 W/m2 in osmotic energy harvesting	1086:1155	This system could deliver an output power of approximately 4.9 W/m2 in osmotic energy harvesting.					
35725162	1	52	attach	linked	288:293	arg2	nanochannels					258:269	temperature sensing nanochannels	238:269	temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane	238:363	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	1	52	attach	linked	288:293	arg1	gating					304:309	photo gating	298:309	photo gating	298:309	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	1	53	theme	mammalian	160:168	arg1	system					178:183	the mammalian sensory system	156:183	the mammalian sensory system to seek comfortable living environment	156:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	7	54	theme	simple	1180:1185	arg1	principle					1221:1229	a simple photothermal-gating ion transport principle	1178:1229	a simple photothermal-gating ion transport principle in laminar RC membrane	1178:1252	Our results suggest a simple photothermal-gating ion transport principle in laminar RC membrane.					
35725162	0	55	theme	power	97:101	arg1	harvesting					103:112	high-performance photothermal-gating osmotic power harvesting	52:112	high-performance photothermal-gating osmotic power harvesting	52:112	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	2	56	theme	membrane	444:451	arg1	membrane					444:451	laminar regenerated cellulose (RC) membrane	409:451	laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	409:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	56	theme	membrane	444:451	arg1	composite					396:404	the composite	392:404	the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	392:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	1	57	theme	sensory	170:176	arg1	system					178:183	the mammalian sensory system	156:183	the mammalian sensory system to seek comfortable living environment	156:222	Inspired by acute temperature sensors in the mammalian sensory system to seek comfortable living environment, we construct temperature sensing nanochannels that are tightly linked to photo gating to form photothermal controlled nanochannels membrane.					
35725162	2	58	theme	RC	440:441	arg1	membrane					444:451	laminar regenerated cellulose (RC) membrane	409:451	laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate	409:644	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	0	59	theme	osmotic	89:95	arg1	harvesting					103:112	high-performance photothermal-gating osmotic power harvesting	52:112	high-performance photothermal-gating osmotic power harvesting	52:112	Laminar regenerated cellulose membrane employed for high-performance photothermal-gating osmotic power harvesting.					
35725162	2	60	from	regeneration	479:490	arg1	nanochannels					590:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	60	from	regeneration	479:490	arg1	liquid					542:547	liquid	542:547	liquid	542:547	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	61	from	dissolution	463:473	arg1	nanochannels					590:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	poly-l-lysine (PLL)-modified conical nanochannels	553:601	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	61	from	dissolution	463:473	arg1	liquid					542:547	liquid	542:547	liquid	542:547	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	62	theme	cellulose	495:503	arg1	regeneration					479:490	regeneration	479:490	regeneration	479:490	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35725162	2	62	theme	cellulose	495:503	arg1	dissolution					463:473	dissolution	463:473	dissolution	463:473	This membrane arises from the composite of laminar regenerated cellulose (RC) membrane formed by dissolution and regeneration of cellulose in the novel superbase-derived ionic liquid and poly-l-lysine (PLL)-modified conical nanochannels polyethylene terephthalate (PET) substrate.					
35034580	7	0	theme	alginate	1098:1105	arg1	gel					1107:1109	alginate gel	1098:1109	alginate gel	1098:1109	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	0	1	from	property	15:22	arg1	gel					64:66	alginate gel	55:66	alginate gel for ofloxacin in the wastewater	55:98	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	2	2	with	particles	423:431	arg1	polymers					438:445	polymers	438:445	polymers	438:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	3	theme	good	324:327	arg1	way					329:331	a good way	322:331	a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers	322:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	3	theme	good	324:327	arg1	synthesis					293:301	In-situ MOF synthesis	281:301	In-situ MOF synthesis in alginate gel	281:317	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	1	4	theme	powder	217:222	arg1	form					224:227	powder form	217:227	powder form	217:227	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	4	5	from	ZIF-8	645:649	arg1	gel					663:665	alginate gel	654:665	alginate gel	654:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	2	6	from	synthesis	293:301	arg1	gel					315:317	alginate gel	306:317	alginate gel	306:317	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	7	7	theme	ZIF-8	1089:1093	arg1	material					1134:1141	an appropriate material	1119:1141	an appropriate material for the removal of ofloxacin in the wastewater	1119:1188	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	7	7	theme	ZIF-8	1089:1093	arg1	synthesis					1076:1084	in-situ synthesis	1068:1084	in-situ synthesis of ZIF-8 in alginate gel	1068:1109	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	7	8	from	material	1134:1141	arg1	wastewater					1179:1188	the wastewater	1175:1188	the wastewater	1175:1188	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	4	9	dep	mg/g	790:793	arg1	160.6 ± 1.3					778:788	160.6 ± 1.3	778:788	160.6 ± 1.3	778:788	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	7	10	theme	appropriate	1122:1132	arg1	material					1134:1141	an appropriate material	1119:1141	an appropriate material for the removal of ofloxacin in the wastewater	1119:1188	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	7	10	theme	appropriate	1122:1132	arg1	synthesis					1076:1084	in-situ synthesis	1068:1084	in-situ synthesis of ZIF-8 in alginate gel	1068:1109	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	4	11	theme	in-situ	624:630	arg1	synthesis					632:640	in-situ synthesis	624:640	in-situ synthesis of ZIF-8 in alginate gel	624:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	3	12	contain	has	574:576	arg1	synthesis					456:464	In-situ synthesis	448:464	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel	448:524	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	3	12	contain	has	574:576	arg2	pores					583:587	many pores	578:587	many pores inside	578:594	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	4	13	theme	ofloxacin	695:703	arg1	%					690:690	97.7 ± 0.9%	680:690	97.7 ± 0.9% of ofloxacin	680:703	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	4	13	theme	ofloxacin	695:703	arg1	ofloxacin					695:703	ofloxacin	695:703	ofloxacin	695:703	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	6	14	theme	adsorption	976:985	arg1	efficiency					987:996	the adsorption efficiency	972:996	the adsorption efficiency	972:996	Moreover, the adsorption efficiency can reach 85.5% even after four cycles of adsorption.					
35034580	3	15	with	beads	544:548	arg1	wrinkles					561:568	rough wrinkles	555:568	rough wrinkles	555:568	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	1	16	theme	general	201:207	arg1	MOFs					209:212	the general MOFs	197:212	the general MOFs in powder form	197:227	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	1	16	theme	general	201:207	arg1	disadvantageous					232:246	disadvantageous	232:246	disadvantageous	232:246	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	1	17	theme	pollutants	185:194	arg1	removal					166:172	the removal	162:172	the removal of organic pollutants	162:194	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	2	18	theme	MOF	349:351	arg1	different					395:403	different	395:403	different	395:403	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	18	theme	MOF	349:351	arg1	composite					353:361	an MOF composite	346:361	an MOF composite	346:361	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	0	19	theme	adsorption	4:13	arg1	property					15:22	The adsorption property	0:22	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.	0:99	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	2	20	from	particles	423:431	arg1	different					395:403	different	395:403	different	395:403	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	20	from	particles	423:431	arg1	composite					353:361	an MOF composite	346:361	an MOF composite	346:361	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	7	21	theme	in-situ	1068:1074	arg1	material					1134:1141	an appropriate material	1119:1141	an appropriate material for the removal of ofloxacin in the wastewater	1119:1188	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	7	21	theme	in-situ	1068:1074	arg1	synthesis					1076:1084	in-situ synthesis	1068:1084	in-situ synthesis of ZIF-8 in alginate gel	1068:1109	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	4	22	from	gel	663:665	arg1	synthesis					632:640	in-situ synthesis	624:640	in-situ synthesis of ZIF-8 in alginate gel	624:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	2	23	theme	MOF	289:291	arg1	way					329:331	a good way	322:331	a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers	322:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	23	theme	MOF	289:291	arg1	synthesis					293:301	In-situ MOF synthesis	281:301	In-situ MOF synthesis in alginate gel	281:317	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	3	24	theme	inside	589:594	arg1	pores					583:587	many pores	578:587	many pores inside	578:594	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	3	25	from	synthesis	456:464	arg1	gel					522:524	alginate gel	513:524	alginate gel	513:524	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	2	26	theme	In-situ	281:287	arg1	way					329:331	a good way	322:331	a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers	322:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	2	26	theme	In-situ	281:287	arg1	synthesis					293:301	In-situ MOF synthesis	281:301	In-situ MOF synthesis in alginate gel	281:317	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	4	27	theme	alginate	654:661	arg1	gel					663:665	alginate gel	654:665	alginate gel	654:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	1	28	theme	practical	257:265	arg1	applications					267:278	their practical applications	251:278	their practical applications	251:278	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	5	29	theme	gel	887:889	arg1	adsorption					904:913	the solvent exchange and gel microchannel adsorption	862:913	adsorption	904:913	During the adsorption, ofloxacin is first brought into the gel by the solvent exchange and gel microchannel adsorption, and it can then be absorbed by in-situ ZIF-8.					
35034580	7	30	from	synthesis	1076:1084	arg1	gel					1107:1109	alginate gel	1098:1109	alginate gel	1098:1109	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	5	31	theme	solvent	866:872	arg1	exchange					874:881	the solvent exchange and gel microchannel adsorption	862:913	exchange	874:881	During the adsorption, ofloxacin is first brought into the gel by the solvent exchange and gel microchannel adsorption, and it can then be absorbed by in-situ ZIF-8.					
35034580	1	32	theme	organic	177:183	arg1	pollutants					185:194	organic pollutants	177:194	organic pollutants	177:194	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	0	33	theme	synthesis	35:43	arg1	property					15:22	The adsorption property	0:22	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.	0:99	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	0	34	from	gel	64:66	arg1	wastewater					89:98	the wastewater	85:98	the wastewater	85:98	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	4	35	theme	equilibrium	737:747	arg1	mg/g					790:793	mg/g	790:793	mg/g	790:793	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	4	35	theme	equilibrium	737:747	arg1	capacity					760:767	the equilibrium adsorption capacity	733:767	the equilibrium adsorption capacity	733:767	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	2	36	theme	many	367:370	arg1	applications					372:383	many applications	367:383	many applications	367:383	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	0	37	theme	in-situ	27:33	arg1	synthesis					35:43	in-situ synthesis	27:43	in-situ synthesis of MOF	27:50	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	3	38	theme	beads	544:548	arg1	form					536:539	the form	532:539	the form of beads with rough wrinkles	532:568	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	0	39	theme	MOF	48:50	arg1	synthesis					35:43	in-situ synthesis	27:43	in-situ synthesis of MOF	27:50	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	1	40	from	MOFs	209:212	arg1	form					224:227	powder form	217:227	powder form	217:227	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	3	41	theme	many	578:581	arg1	pores					583:587	many pores	578:587	many pores inside	578:594	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	3	42	theme	In-situ	448:454	arg1	synthesis					456:464	In-situ synthesis	448:464	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel	448:524	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	2	43	theme	blending	410:417	arg1	particles					423:431	blending MOF particles	410:431	blending MOF particles with polymers	410:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	4	44	theme	adsorption	749:758	arg1	mg/g					790:793	mg/g	790:793	mg/g	790:793	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	4	44	theme	adsorption	749:758	arg1	capacity					760:767	the equilibrium adsorption capacity	733:767	the equilibrium adsorption capacity	733:767	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	7	45	theme	ofloxacin	1162:1170	arg1	removal					1151:1157	the removal	1147:1157	the removal of ofloxacin	1147:1170	We believe that in-situ synthesis of ZIF-8 in alginate gel will be an appropriate material for the removal of ofloxacin in the wastewater.					
35034580	5	46	theme	in-situ	947:953	arg1	ZIF-8					955:959	in-situ ZIF-8	947:959	in-situ ZIF-8	947:959	During the adsorption, ofloxacin is first brought into the gel by the solvent exchange and gel microchannel adsorption, and it can then be absorbed by in-situ ZIF-8.					
35034580	4	47	theme	ofloxacin	710:718	arg1	solution					720:727	ofloxacin solution	710:727	ofloxacin solution	710:727	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	1	48	theme	metal-organic	110:122	arg1	MOFs					136:139	MOFs	136:139	MOFs	136:139	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	1	48	theme	metal-organic	110:122	arg1	frameworks					124:133	metal-organic frameworks	110:133	metal-organic frameworks (MOFs)	110:140	Although metal-organic frameworks (MOFs) are advantageous to the removal of organic pollutants, the general MOFs in powder form is disadvantageous to their practical applications.					
35034580	3	49	theme	alginate	513:520	arg1	gel					522:524	alginate gel	513:524	alginate gel	513:524	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	5	50	theme	microchannel	891:902	arg1	adsorption					904:913	the solvent exchange and gel microchannel adsorption	862:913	adsorption	904:913	During the adsorption, ofloxacin is first brought into the gel by the solvent exchange and gel microchannel adsorption, and it can then be absorbed by in-situ ZIF-8.					
35034580	4	51	theme	ZIF-8	645:649	arg1	synthesis					632:640	in-situ synthesis	624:640	in-situ synthesis of ZIF-8 in alginate gel	624:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	2	52	theme	alginate	306:313	arg1	gel					315:317	alginate gel	306:317	alginate gel	306:317	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	0	53	theme	alginate	55:62	arg1	gel					64:66	alginate gel	55:66	alginate gel for ofloxacin in the wastewater	55:98	The adsorption property of in-situ synthesis of MOF in alginate gel for ofloxacin in the wastewater.					
35034580	3	54	theme	Imidazolate	478:488	arg1	synthesis					456:464	In-situ synthesis	448:464	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel	448:524	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	4	55	from	synthesis	632:640	arg1	gel					663:665	alginate gel	654:665	alginate gel	654:665	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
35034580	6	56	theme	adsorption	1040:1049	arg1	cycles					1030:1035	four cycles	1025:1035	four cycles of adsorption	1025:1049	Moreover, the adsorption efficiency can reach 85.5% even after four cycles of adsorption.					
35034580	2	57	theme	MOF	419:421	arg1	particles					423:431	blending MOF particles	410:431	blending MOF particles with polymers	410:445	In-situ MOF synthesis in alginate gel is a good way to fabricate an MOF composite for many applications, which is different from blending MOF particles with polymers.					
35034580	3	58	theme	rough	555:559	arg1	wrinkles					561:568	rough wrinkles	555:568	rough wrinkles	555:568	In-situ synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) in alginate gel is in the form of beads with rough wrinkles and has many pores inside.					
35034580	4	59	dep	160.6 ± 1.3	778:788	arg1	to					775:776	to	775:776	to	775:776	When used as an absorbent, in-situ synthesis of ZIF-8 in alginate gel could remove 97.7 ± 0.9% of ofloxacin from ofloxacin solution and the equilibrium adsorption capacity is up to 160.6 ± 1.3 mg/g.					
37025081	3	0	dep	have	756:759	arg1	make					836:839	make	836:839	make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds	836:923	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	2	1	theme	high	607:610	arg1	potential					612:620	high potential	607:620	high potential to help address this health problem	607:656	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	3	2	theme	process	867:873	arg1	use					841:843	use	841:843	use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds	841:923	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	1	3	theme	defects	254:260	arg1	incidence					236:244	the incidence	232:244	the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically	232:393	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	2	4	theme	carboxymethylcellulose	470:491	arg1	design					412:417	the design	408:417	the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure	408:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	0	5	from	activity	11:18	arg1	3D					93:94	3D	93:94	3D	93:94	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	8	6	with	demeanor	1729:1736	arg1	models					1747:1752	rat models	1743:1752	rat models	1743:1752	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	1	7	theme	regenerative	171:182	arg1	osteogenesis					184:195	regenerative osteogenesis	171:195	regenerative osteogenesis	171:195	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	2	8	theme	carbonate	518:526	arg1	design					412:417	the design	408:417	the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure	408:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	9	theme	structure	590:598	arg1	terms					560:564	terms	560:564	terms of composition and bone structure	560:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	10	theme	calcium	510:516	arg1	carbonate					518:526	calcium carbonate	510:526	calcium carbonate	510:526	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	11	with	design	412:417	arg1	characteristics					541:555	similar characteristics	533:555	similar characteristics in terms of composition and bone structure	533:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	12	theme	bone	585:588	arg1	structure					590:598	bone structure	585:598	bone structure	585:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	13	theme	health	643:648	arg1	problem					650:656	this health problem	638:656	this health problem	638:656	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	3	14	theme	three-dimensional	885:901	arg1	scaffolds					915:923	three-dimensional (3D) porous scaffolds	885:923	three-dimensional (3D) porous scaffolds	885:923	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	3	15	theme	polymer	810:816	arg1	chains					818:823	the polymer chains	806:823	the polymer chains used	806:828	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	8	16	theme	calcium	1526:1532	arg1	scaffolds					1555:1563	the calcium carbonate-containing scaffolds	1522:1563	the calcium carbonate-containing scaffolds stabilized by physical bonds	1522:1592	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	6	17	theme	calcium	1275:1281	arg1	deposits					1283:1290	calcium deposits	1275:1290	calcium deposits in the materials with CaCO3 and ZnO	1275:1326	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	6	18	theme	designed	1179:1186	arg1	scaffolds					1188:1196	the designed scaffolds	1175:1196	the designed scaffolds	1175:1196	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	8	19	theme	future	1698:1703	arg1	tests					1705:1709	future tests	1698:1709	future tests	1698:1709	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	0	20	theme	physical	120:127	arg1	links					129:133	physical links	120:133	physical links for bone tissue engineering	120:161	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	3	21	theme	research	709:716	arg1	scaffolds					691:699	the scaffolds	687:699	the scaffolds of this research	687:716	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	3	22	theme	chains	818:823	arg1	biofunctionality					765:780	the biofunctionality	761:780	the biofunctionality of the active groups of the polymer chains used	761:828	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	8	23	theme	carbonate-containing	1534:1553	arg1	scaffolds					1555:1563	the calcium carbonate-containing scaffolds	1522:1563	the calcium carbonate-containing scaffolds stabilized by physical bonds	1522:1592	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	7	24	theme	type	1441:1444	arg1	antibodies					1456:1465	runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies	1379:1465	runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies	1379:1465	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	2	25	theme	chitosan	460:467	arg1	scaffold					447:454	scaffold	447:454	scaffold	447:454	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	25	theme	chitosan	460:467	arg1	carboxymethylcellulose					470:491	carboxymethylcellulose	470:491	carboxymethylcellulose	470:491	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	25	theme	chitosan	460:467	arg1	oxide					499:503	zinc oxide	494:503	zinc oxide	494:503	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	25	theme	chitosan	460:467	arg1	biomaterial					434:444	a polymeric biomaterial	422:444	a polymeric biomaterial (scaffold) of chitosan	422:467	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	25	theme	chitosan	460:467	arg1	carbonate					518:526	calcium carbonate	510:526	calcium carbonate	510:526	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	6	26	with	analyzes	1234:1241	arg1	staining					1261:1268	alizarin red staining	1248:1268	alizarin red staining	1248:1268	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	0	27	dep	scaffolds	96:104	arg1	stabilized					106:115	stabilized	106:115	scaffolds stabilized by physical links for bone tissue engineering	96:161	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	8	28	theme	rat	1743:1745	arg1	models					1747:1752	rat models	1743:1752	rat models	1743:1752	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	0	29	theme	Biological	0:9	arg1	activity					11:18	Biological activity	0:18	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D	0:94	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	8	30	theme	physical	1579:1586	arg1	bonds					1588:1592	physical bonds	1579:1592	physical bonds	1579:1592	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	6	31	theme	red	1257:1259	arg1	staining					1261:1268	alizarin red staining	1248:1268	alizarin red staining	1248:1268	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	3	32	theme	porous	908:913	arg1	scaffolds					915:923	three-dimensional (3D) porous scaffolds	885:923	three-dimensional (3D) porous scaffolds	885:923	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	1	33	theme	clinical	210:217	arg1	need					219:222	a clinical need	208:222	a clinical need	208:222	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	2	34	theme	biomaterial	434:444	arg1	design					412:417	the design	408:417	the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure	408:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	1	35	theme	pathologies	285:295	arg1	problems					365:372	problems	365:372	problems presented surgically	365:393	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	1	35	theme	pathologies	285:295	arg1	pathologies					285:295	pathologies	285:295	pathologies ranging from congenital anomalies to traumatic injuries	285:351	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	1	35	theme	pathologies	285:295	arg1	groups					275:280	groups	275:280	groups of pathologies ranging from congenital anomalies to traumatic injuries	275:351	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	0	36	theme	bone	139:142	arg1	engineering					151:161	bone tissue engineering	139:161	bone tissue engineering	139:161	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	7	37	theme	factor	1406:1411	arg1	type					1413:1416	runt-related transcription factor type 2	1379:1418	runt-related transcription factor type 2 (RUNX2)	1379:1426	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	7	37	theme	factor	1406:1411	arg1	RUNX2					1421:1425	RUNX2	1421:1425	RUNX2	1421:1425	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	7	38	theme	type	1413:1416	arg1	antibodies					1456:1465	runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies	1379:1465	runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies	1379:1465	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	2	39	theme	polymeric	424:432	arg1	scaffold					447:454	scaffold	447:454	scaffold	447:454	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	2	39	theme	polymeric	424:432	arg1	biomaterial					434:444	a polymeric biomaterial	422:444	a polymeric biomaterial (scaffold) of chitosan	422:467	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	7	40	theme	collagen	1432:1439	arg1	type					1441:1444	collagen type 1	1432:1446	collagen type 1 (COL-1)	1432:1454	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	7	40	theme	collagen	1432:1439	arg1	COL-1					1449:1453	COL-1	1449:1453	COL-1	1449:1453	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	6	41	theme	biocompatibility	1139:1154	arg1	tests					1156:1160	The biocompatibility tests	1135:1160	The biocompatibility tests	1135:1160	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	8	42	theme	bone	1758:1761	arg1	studies					1775:1781	bone engineering studies	1758:1781	bone engineering studies	1758:1781	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	0	43	theme	oxide	62:66	arg1	activity					11:18	Biological activity	0:18	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D	0:94	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	3	44	theme	physical	735:742	arg1	hydrogel					744:751	a physical hydrogel	733:751	a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds	733:923	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	2	45	theme	similar	533:539	arg1	characteristics					541:555	similar characteristics	533:555	similar characteristics in terms of composition and bone structure	533:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	6	46	theme	alizarin	1248:1255	arg1	staining					1261:1268	alizarin red staining	1248:1268	alizarin red staining	1248:1268	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	7	47	theme	Osteoinduction	1329:1342	arg1	assays					1344:1349	Osteoinduction assays	1329:1349	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies	1329:1465	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	1	48	theme	due	225:227	arg1	need					219:222	a clinical need	208:222	a clinical need	208:222	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	0	49	theme	chitosan-carboxymethylcellulose-zinc	25:60	arg1	oxide					62:66	a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate	23:88	oxide	62:66	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	1	50	theme	congenital	310:319	arg1	anomalies					321:329	congenital anomalies	310:329	congenital anomalies	310:329	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	0	51	theme	tissue	144:149	arg1	engineering					151:161	bone tissue engineering	139:161	bone tissue engineering	139:161	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	3	52	theme	active	789:794	arg1	groups					796:801	the active groups	785:801	the active groups	785:801	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	0	53	theme	calcium	72:78	arg1	carbonate					80:88	a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate	23:88	carbonate	80:88	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	5	54	dep	cell	1101:1104	arg1	viability					1124:1132	viability	1124:1132	viability	1124:1132	The scaffolds presented morphology with pore size and interconnectivity that favor the need for cell proliferation and viability.					
37025081	5	54	dep	cell	1101:1104	arg1	proliferation					1106:1118	proliferation	1106:1118	proliferation	1106:1118	The scaffolds presented morphology with pore size and interconnectivity that favor the need for cell proliferation and viability.					
37025081	8	55	theme	engineering	1763:1773	arg1	studies					1775:1781	bone engineering studies	1758:1781	bone engineering studies	1758:1781	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	2	56	theme	zinc	494:497	arg1	oxide					499:503	zinc oxide	494:503	zinc oxide	494:503	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	7	57	theme	transcription	1392:1404	arg1	factor					1406:1411	runt-related transcription factor	1379:1411	runt-related transcription factor type 2 (RUNX2)	1379:1426	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	7	58	from	expression	1475:1484	arg1	cells					1504:1508	differentiated cells	1489:1508	differentiated cells	1489:1508	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	8	59	from	use	1691:1693	arg1	tests					1705:1709	future tests	1698:1709	future tests	1698:1709	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	2	60	theme	composition	569:579	arg1	terms					560:564	terms	560:564	terms of composition and bone structure	560:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	4	61	theme	biological	950:959	arg1	properties					961:970	The physicochemical and biological properties	926:970	The physicochemical and biological properties of the scaffolds	926:987	The physicochemical and biological properties of the scaffolds were evaluated.					
37025081	3	62	dep	three-dimensional	885:901	arg1	3D					904:905	3D	904:905	3D	904:905	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	1	63	theme	traumatic	334:342	arg1	injuries					344:351	traumatic injuries	334:351	traumatic injuries	334:351	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37025081	5	64	theme	pore	1045:1048	arg1	size					1050:1053	pore size	1045:1053	pore size	1045:1053	The scaffolds presented morphology with pore size and interconnectivity that favor the need for cell proliferation and viability.					
37025081	4	65	theme	scaffolds	979:987	arg1	properties					961:970	The physicochemical and biological properties	926:970	The physicochemical and biological properties of the scaffolds	926:987	The physicochemical and biological properties of the scaffolds were evaluated.					
37025081	3	66	theme	groups	796:801	arg1	biofunctionality					765:780	the biofunctionality	761:780	the biofunctionality of the active groups of the polymer chains used	761:828	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	7	67	theme	runt-related	1379:1390	arg1	factor					1406:1411	runt-related transcription factor	1379:1411	runt-related transcription factor type 2 (RUNX2)	1379:1426	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	6	68	with	materials	1299:1307	arg1	ZnO					1324:1326	ZnO	1324:1326	ZnO	1324:1326	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	6	68	with	materials	1299:1307	arg1	CaCO3					1314:1318	CaCO3	1314:1318	CaCO3	1314:1318	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	6	69	from	deposits	1283:1290	arg1	materials					1299:1307	the materials	1295:1307	the materials with CaCO3 and ZnO	1295:1326	The biocompatibility tests confirm that the designed scaffolds do not present cytotoxicity and the analyzes with alizarin red staining show calcium deposits in the materials with CaCO3 and ZnO.					
37025081	2	70	theme	oxide	499:503	arg1	design					412:417	the design	408:417	the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure	408:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	7	71	theme	osteogenic	1354:1363	arg1	lineage					1365:1371	osteogenic lineage	1354:1371	osteogenic lineage	1354:1371	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	8	72	contain	have	1594:1597	arg1	scaffolds					1555:1563	the calcium carbonate-containing scaffolds	1522:1563	the calcium carbonate-containing scaffolds stabilized by physical bonds	1522:1592	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	8	72	contain	have	1594:1597	arg2	characteristics					1599:1613	characteristics	1599:1613	characteristics	1599:1613	Therefore, the calcium carbonate-containing scaffolds stabilized by physical bonds have characteristics of being non-cytotoxic, bioactive, and osteoinductive, which motivate their use in future tests to evaluate their demeanor with rat models for bone engineering studies.					
37025081	0	73	theme	carbonate	80:88	arg1	activity					11:18	Biological activity	0:18	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D	0:94	Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering.					
37025081	7	74	theme	differentiated	1489:1502	arg1	cells					1504:1508	differentiated cells	1489:1508	differentiated cells	1489:1508	Osteoinduction assays to osteogenic lineage using runt-related transcription factor type 2 (RUNX2) and collagen type 1 (COL-1) antibodies allowed expression in differentiated cells.					
37025081	2	75	from	characteristics	541:555	arg1	terms					560:564	terms	560:564	terms of composition and bone structure	560:598	This is why the design of a polymeric biomaterial (scaffold) of chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms of composition and bone structure offers high potential to help address this health problem.					
37025081	4	76	theme	physicochemical	930:944	arg1	properties					961:970	The physicochemical and biological properties	926:970	The physicochemical and biological properties of the scaffolds	926:987	The physicochemical and biological properties of the scaffolds were evaluated.					
37025081	3	77	theme	lyophilization	852:865	arg1	process					867:873	the lyophilization process	848:873	the lyophilization process	848:873	The technique for obtaining the scaffolds of this research was to develop a physical hydrogel to have the biofunctionality of the active groups of the polymer chains used, then make use of the lyophilization process to obtain three-dimensional (3D) porous scaffolds.					
37025081	1	78	theme	bone	249:252	arg1	defects					254:260	bone defects	249:260	bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically	249:393	Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups of pathologies ranging from congenital anomalies to traumatic injuries, as well as problems presented surgically.					
37148947	5	0	dep	rate	730:733	arg1	the					713:715	the	713:715	the	713:715	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	4	1	theme	orange	595:600	arg1	dyes					602:605	reactive orange dyes	586:605	reactive orange dyes	586:605	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	4	2	theme	as-prepared	444:454	arg1	membranes					468:476	The as-prepared nanofibrous membranes	440:476	The as-prepared nanofibrous membranes	440:476	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	1	3	theme	excellent	161:169	arg1	conductivity					182:193	its excellent electrical conductivity	157:193	its excellent electrical conductivity	157:193	Polyaniline is widely used in the field of electrochemistry due to its excellent electrical conductivity.					
37148947	4	4	theme	reactive	586:593	arg1	orange					595:600	reactive orange	586:600	reactive orange dyes	586:605	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	5	5	theme	dye	717:719	arg1	rate					730:733	dye transfer rate	717:733	dye transfer rate	717:733	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	7	6	theme	conductive	1038:1047	arg1	polymer					1049:1055	conductive polymer	1038:1055	conductive polymer	1038:1055	This study provides a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment.					
37148947	6	7	theme	spontaneous	951:961	arg1	adsorption					973:982	spontaneous monolayer adsorption	951:982	spontaneous monolayer adsorption	951:982	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	6	7	theme	spontaneous	951:961	arg1	adsorption					912:921	the adsorption	908:921	the adsorption of the two anionic dyes	908:945	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	5	8	theme	transfer	721:728	arg1	rate					730:733	dye transfer rate	717:733	dye transfer rate	717:733	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	5	9	theme	composite	788:796	arg1	membrane					798:805	the composite membrane	784:805	the composite membrane	784:805	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	4	10	theme	618.0 mg/g	549:558	arg1	capacity					522:529	significantly improved adsorption capacity	488:529	significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane	488:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	4	11	theme	nanofibrous	456:466	arg1	membranes					468:476	The as-prepared nanofibrous membranes	440:476	The as-prepared nanofibrous membranes	440:476	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	1	12	theme	electrical	171:180	arg1	conductivity					182:193	its excellent electrical conductivity	157:193	its excellent electrical conductivity	157:193	Polyaniline is widely used in the field of electrochemistry due to its excellent electrical conductivity.					
37148947	5	13	theme	membrane	798:805	arg1	conductivity					768:779	the enhanced conductivity	755:779	the enhanced conductivity of the composite membrane	755:805	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	4	14	theme	blue	573:576	arg1	acid					568:571	acid blue 113	568:580	acid blue 113	568:580	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	3	15	with	membranes	334:342	arg1	diameter					357:364	average diameter	349:364	average diameter ranging from 200 to 300 nm	349:391	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	0	16	theme	dye	9:11	arg1	adsorption					13:22	Enhanced dye adsorption	0:22	Enhanced dye adsorption with conductive polyaniline	0:50	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	6	17	theme	anionic	934:940	arg1	dyes					942:945	the two anionic dyes	926:945	the two anionic dyes	926:945	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	5	18	theme	doped	686:690	arg1	polyaniline					692:702	The doped polyaniline	682:702	The doped polyaniline	682:702	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	7	19	theme	feasible	1007:1014	arg1	strategy					1016:1023	a feasible strategy	1005:1023	a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment	1005:1136	This study provides a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment.					
37148947	3	20	theme	average	349:355	arg1	diameter					357:364	average diameter	349:364	average diameter ranging from 200 to 300 nm	349:391	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	0	21	theme	Enhanced	0:7	arg1	adsorption					13:22	Enhanced dye adsorption	0:22	Enhanced dye adsorption with conductive polyaniline	0:50	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	6	22	theme	thermodynamic	879:891	arg1	data					893:896	thermodynamic data	879:896	thermodynamic data	879:896	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	3	23	theme	chitosan/polyaniline	291:310	arg1	membranes					334:342	chitosan/polyaniline nanofibrous composite membranes	291:342	chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm	291:391	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	6	24	theme	rate-limiting	855:867	arg1	step					869:872	the rate-limiting step	851:872	the rate-limiting step	851:872	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	6	24	theme	rate-limiting	855:867	arg1	chemisorption					833:845	chemisorption	833:845	chemisorption	833:845	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	3	25	theme	nanofibrous	312:322	arg1	membranes					334:342	chitosan/polyaniline nanofibrous composite membranes	291:342	chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm	291:391	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	6	26	theme	dyes	942:945	arg1	adsorption					973:982	spontaneous monolayer adsorption	951:982	spontaneous monolayer adsorption	951:982	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	6	26	theme	dyes	942:945	arg1	adsorption					912:921	the adsorption	908:921	the adsorption of the two anionic dyes	908:945	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	5	27	theme	enhanced	759:766	arg1	conductivity					768:779	the enhanced conductivity	755:779	the enhanced conductivity of the composite membrane	755:805	The doped polyaniline promoted the dye transfer rate and capacity due to the enhanced conductivity of the composite membrane.					
37148947	2	28	theme	adsorption	250:259	arg1	property					261:268	enhancing adsorption property	240:268	enhancing adsorption property	240:268	However, its effectiveness and mechanism of enhancing adsorption property are unclear.					
37148947	0	29	theme	conductive	29:38	arg1	polyaniline					40:50	conductive polyaniline	29:50	conductive polyaniline	29:50	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	2	30	theme	enhancing	240:248	arg1	property					261:268	enhancing adsorption property	240:268	enhancing adsorption property	240:268	However, its effectiveness and mechanism of enhancing adsorption property are unclear.					
37148947	7	31	theme	performance	1090:1100	arg1	adsorbents					1102:1111	high performance adsorbents	1085:1111	high performance adsorbents for wastewater treatment	1085:1136	This study provides a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment.					
37148947	0	32	theme	chitosan	58:65	arg1	membranes					79:87	chitosan nanofibrous membranes	58:87	chitosan nanofibrous membranes	58:87	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	4	33	theme	814.9 mg/g	534:543	arg1	capacity					522:529	significantly improved adsorption capacity	488:529	significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane	488:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	0	34	with	adsorption	13:22	arg1	polyaniline					40:50	conductive polyaniline	29:50	conductive polyaniline	29:50	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	6	35	theme	monolayer	963:971	arg1	adsorption					973:982	spontaneous monolayer adsorption	951:982	spontaneous monolayer adsorption	951:982	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	6	35	theme	monolayer	963:971	arg1	adsorption					912:921	the adsorption	908:921	the adsorption of the two anionic dyes	908:945	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	3	36	dep	300 nm	386:391	arg1	to					383:384	to	383:384	to	383:384	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	6	37	theme	Kinetic	808:814	arg1	data					816:819	Kinetic data	808:819	Kinetic data	808:819	Kinetic data showed that chemisorption was the rate-limiting step, and thermodynamic data indicated the adsorption of the two anionic dyes was spontaneous monolayer adsorption.					
37148947	1	38	used	used	112:115	arg2	Polyaniline					90:100	Polyaniline	90:100	Polyaniline	90:100	Polyaniline is widely used in the field of electrochemistry due to its excellent electrical conductivity.					
37148947	3	39	theme	composite	324:332	arg1	membranes					334:342	chitosan/polyaniline nanofibrous composite membranes	291:342	chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm	291:391	Herein, chitosan/polyaniline nanofibrous composite membranes with average diameter ranging from 200 to 300 nm were fabricated by electrospinning technology.					
37148947	7	40	theme	high	1085:1088	arg1	adsorbents					1102:1111	high performance adsorbents	1085:1111	high performance adsorbents for wastewater treatment	1085:1136	This study provides a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment.					
37148947	4	41	theme	pure	658:661	arg1	membrane					672:679	pure chitosan membrane	658:679	pure chitosan membrane	658:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	7	42	theme	wastewater	1117:1126	arg1	treatment					1128:1136	wastewater treatment	1117:1136	wastewater treatment	1117:1136	This study provides a feasible strategy to introduce conductive polymer into adsorbent to construct high performance adsorbents for wastewater treatment.					
37148947	4	43	theme	adsorption	511:520	arg1	capacity					522:529	significantly improved adsorption capacity	488:529	significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane	488:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	1	44	theme	electrochemistry	133:148	arg1	field					124:128	the field	120:128	the field of electrochemistry due to its excellent electrical conductivity	120:193	Polyaniline is widely used in the field of electrochemistry due to its excellent electrical conductivity.					
37148947	4	45	theme	improved	502:509	arg1	capacity					522:529	significantly improved adsorption capacity	488:529	significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane	488:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
37148947	0	46	theme	nanofibrous	67:77	arg1	membranes					79:87	chitosan nanofibrous membranes	58:87	chitosan nanofibrous membranes	58:87	Enhanced dye adsorption with conductive polyaniline doped chitosan nanofibrous membranes.					
37148947	2	47	theme	property	261:268	arg1	mechanism					227:235	mechanism	227:235	mechanism	227:235	However, its effectiveness and mechanism of enhancing adsorption property are unclear.					
37148947	2	47	theme	property	261:268	arg1	effectiveness					209:221	effectiveness	209:221	effectiveness	209:221	However, its effectiveness and mechanism of enhancing adsorption property are unclear.					
37148947	4	48	theme	chitosan	663:670	arg1	membrane					672:679	pure chitosan membrane	658:679	pure chitosan membrane	658:679	The as-prepared nanofibrous membranes exhibited significantly improved adsorption capacity of 814.9 mg/g and 618.0 mg/g towards acid blue 113 and reactive orange dyes, which were 121.8 % and 99.4 % higher than that of pure chitosan membrane.					
36088011	0	0	theme	life	87:90	arg1	extension					92:100	shelf life extension	81:100	shelf life extension of food	81:108	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	0	1	theme	shelf	81:85	arg1	extension					92:100	shelf life extension	81:100	shelf life extension of food	81:108	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	2	2	theme	lignin	340:345	arg1	nanocrystals					361:372	modified lignin and cellulose nanocrystals	331:372	modified lignin and cellulose nanocrystals	331:372	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36088011	1	3	theme	packaging	249:257	arg1	industry					259:266	the packaging industry	245:266	the packaging industry	245:266	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	6	4	from	results	1047:1053	arg1	packaging					1063:1071	food packaging	1058:1071	food packaging	1058:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	4	5	theme	food	772:775	arg1	packaging					777:785	food packaging	772:785	food packaging	772:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	6	6	theme	maximum	975:981	arg1	absorption					983:992	a maximum absorption	973:992	a maximum absorption of the UV light	973:1008	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	4	7	theme	films	597:601	arg1	modification					544:555	The chemical modification	531:555	The chemical modification	531:555	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	7	theme	films	597:601	arg1	range					584:588	the in-use temperature range	561:588	the in-use temperature range of the films	561:601	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	5	8	theme	smooth	909:914	arg1	texture					916:922	smooth texture	909:922	smooth texture of films	909:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	3	9	theme	alkylation	455:464	arg1	process					466:472	the alkylation process	451:472	the alkylation process followed by chemical modification using epichlorohydrin	451:528	The lignin was extracted via the alkylation process followed by chemical modification using epichlorohydrin.					
36088011	6	10	theme	great	1041:1045	arg1	results					1047:1053	450-200 nm and great results	1026:1053	450-200 nm and great results in food packaging	1026:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	0	11	theme	food	105:108	arg1	extension					92:100	shelf life extension	81:100	shelf life extension of food	81:108	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	6	12	from	range	1017:1021	arg1	packaging					1063:1071	food packaging	1058:1071	food packaging	1058:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	4	13	theme	packaging	777:785	arg1	thermo-sealing					754:767	the thermo-sealing	750:767	the thermo-sealing of food packaging	750:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	6	14	theme	food	1058:1061	arg1	packaging					1063:1071	food packaging	1058:1071	food packaging	1058:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	1	15	theme	natural	179:185	arg1	sources					187:193	natural sources	179:193	natural sources	179:193	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	0	16	theme	food	12:15	arg1	film					27:30	Intelligent food packaging film	0:30	Intelligent food packaging film	0:30	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	4	17	theme	temperature	572:582	arg1	range					584:588	the in-use temperature range	561:588	the in-use temperature range of the films	561:601	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	18	theme	lignin	674:679	arg1	modification					658:669	the chemical modification	645:669	the chemical modification of lignin	645:679	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	0	19	theme	Intelligent	0:10	arg1	film					27:30	Intelligent food packaging film	0:30	Intelligent food packaging film	0:30	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	4	20	theme	in-use	565:570	arg1	range					584:588	the in-use temperature range	561:588	the in-use temperature range of the films	561:601	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	2	21	dep	produced	313:320	arg1	both					375:378	both	375:378	both	375:378	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36088011	5	22	theme	smallest	870:877	arg1	size					879:882	the smallest size	866:882	the smallest size around 300 nm generating smooth texture of films	866:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	6	23	theme	results	1047:1053	arg1	range					1017:1021	the range	1013:1021	the range of 450-200 nm and great results in food packaging	1013:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	5	24	theme	films	927:931	arg1	texture					916:922	smooth texture	909:922	smooth texture of films	909:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	2	25	theme	UV-protection	288:300	arg1	films					302:306	the UV-protection films	284:306	the UV-protection films	284:306	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36088011	6	26	theme	450-200 nm	1026:1035	arg1	results					1047:1053	450-200 nm and great results	1026:1053	450-200 nm and great results in food packaging	1026:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	0	27	theme	packaging	17:25	arg1	film					27:30	Intelligent food packaging film	0:30	Intelligent food packaging film	0:30	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	4	28	theme	thermal	694:700	arg1	parameter					733:741	an essential parameter	720:741	an essential parameter during the thermo-sealing of food packaging	720:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	28	theme	thermal	694:700	arg1	property					702:709	the thermal property	690:709	the thermal property which is an essential parameter during the thermo-sealing of food packaging	690:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	28	theme	thermal	694:700	arg1	FTIR					625:628	FTIR	625:628	FTIR	625:628	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	28	theme	thermal	694:700	arg1	TGA					634:636	TGA	634:636	TGA	634:636	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	2	29	theme	Argania	404:410	arg1	nutshell					412:419	the Argania nutshell	400:419	the Argania nutshell	400:419	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36088011	0	30	theme	lignin	43:48	arg1	nanocrystals					64:75	lignin and cellulose nanocrystals	43:75	lignin and cellulose nanocrystals for shelf life extension of food	43:108	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	3	31	theme	chemical	486:493	arg1	modification					495:506	chemical modification	486:506	chemical modification using epichlorohydrin	486:528	The lignin was extracted via the alkylation process followed by chemical modification using epichlorohydrin.					
36088011	6	32	theme	produced	947:954	arg1	films					956:960	the produced films	943:960	the produced films	943:960	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	5	33	theme	acid	835:838	arg1	treatment					851:859	acid hydrolysis treatment	835:859	acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films	835:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	4	34	theme	chemical	535:542	arg1	modification					544:555	The chemical modification	531:555	The chemical modification	531:555	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	6	35	theme	UV	1001:1002	arg1	light					1004:1008	the UV light	997:1008	the UV light	997:1008	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	5	36	theme	hydrolysis	840:849	arg1	treatment					851:859	acid hydrolysis treatment	835:859	acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films	835:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	0	37	theme	cellulose	54:62	arg1	nanocrystals					64:75	lignin and cellulose nanocrystals	43:75	lignin and cellulose nanocrystals for shelf life extension of food	43:108	Intelligent food packaging film containing lignin and cellulose nanocrystals for shelf life extension of food.					
36088011	2	38	theme	modified	331:338	arg1	nanocrystals					361:372	modified lignin and cellulose nanocrystals	331:372	modified lignin and cellulose nanocrystals	331:372	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36088011	1	39	theme	UV-protection	115:127	arg1	films					129:133	The UV-protection films	111:133	The UV-protection films based on renewable materials extracted from natural sources	111:193	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	1	39	theme	UV-protection	115:127	arg1	one					205:207	one	205:207	one	205:207	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	1	39	theme	UV-protection	115:127	arg1	targets					233:239	the most interesting targets	212:239	the most interesting targets for the packaging industry	212:266	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	5	40	with	treatment	851:859	arg1	size					879:882	the smallest size	866:882	the smallest size around 300 nm generating smooth texture of films	866:931	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	6	41	theme	light	1004:1008	arg1	absorption					983:992	a maximum absorption	973:992	a maximum absorption of the UV light	973:1008	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	4	42	theme	essential	723:731	arg1	parameter					733:741	an essential parameter	720:741	an essential parameter during the thermo-sealing of food packaging	720:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	42	theme	essential	723:731	arg1	property					702:709	the thermal property	690:709	the thermal property which is an essential parameter during the thermo-sealing of food packaging	690:785	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	42	theme	essential	723:731	arg1	FTIR					625:628	FTIR	625:628	FTIR	625:628	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	4	42	theme	essential	723:731	arg1	TGA					634:636	TGA	634:636	TGA	634:636	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	6	43	from	packaging	1063:1071	arg1	range					1017:1021	the range	1013:1021	the range of 450-200 nm and great results in food packaging	1013:1071	Finally, the produced films were shown a maximum absorption of the UV light in the range of 450-200 nm and great results in food packaging.					
36088011	1	44	theme	renewable	144:152	arg1	materials					154:162	renewable materials	144:162	renewable materials extracted from natural sources	144:193	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	1	45	theme	interesting	221:231	arg1	targets					233:239	the most interesting targets	212:239	the most interesting targets for the packaging industry	212:266	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	4	46	theme	chemical	649:656	arg1	modification					658:669	the chemical modification	645:669	the chemical modification of lignin	645:679	The chemical modification and the in-use temperature range of the films were investigated via FTIR and TGA, where the chemical modification of lignin improves the thermal property which is an essential parameter during the thermo-sealing of food packaging.					
36088011	1	47	theme	targets	233:239	arg1	targets					233:239	the most interesting targets	212:239	the most interesting targets for the packaging industry	212:266	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	1	47	theme	targets	233:239	arg1	one					205:207	one	205:207	one	205:207	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	1	47	theme	targets	233:239	arg1	films					129:133	The UV-protection films	111:133	The UV-protection films based on renewable materials extracted from natural sources	111:193	The UV-protection films based on renewable materials extracted from natural sources are being one of the most interesting targets for the packaging industry.					
36088011	5	48	theme	other	795:799	arg1	hand					801:804	the other hand	791:804	the other hand	791:804	On the other hand, the CNCs were extracted via acid hydrolysis treatment with the smallest size around 300 nm generating smooth texture of films.					
36088011	2	49	theme	cellulose	351:359	arg1	nanocrystals					361:372	modified lignin and cellulose nanocrystals	331:372	modified lignin and cellulose nanocrystals	331:372	In this paper, the UV-protection films were produced based on modified lignin and cellulose nanocrystals, both were extracted from the Argania nutshell.					
36614324	9	0	theme	well-known	1535:1544	arg1	activity					1556:1563	the well-known catalytic activity	1531:1563	the well-known catalytic activity of the couple Ce3+/Ce4+	1531:1587	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	1	1	theme	worldwide	149:157	arg1	cause					134:138	a leading cause	124:138	a leading cause of death worldwide	124:157	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	1	1	theme	worldwide	149:157	arg1	Cancer					114:119	Cancer	114:119	Cancer	114:119	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	1	2	theme	oxygen	235:240	arg1	species					242:248	reactive oxygen species	226:248	reactive oxygen species	226:248	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	9	3	theme	catalytic	1546:1554	arg1	activity					1556:1563	the well-known catalytic activity	1531:1563	the well-known catalytic activity of the couple Ce3+/Ce4+	1531:1587	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	3	4	theme	major	494:498	arg1	problem					500:506	the major problem	490:506	the major problem related to its use	490:525	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	4	theme	major	494:498	arg1	bioavailability					544:558	its poor oral bioavailability	530:558	its poor oral bioavailability	530:558	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	0	5	theme	Therapeutics	100:111	arg1	Stabilization					83:95	Stabilization	83:95	Stabilization	83:95	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	0	5	theme	Therapeutics	100:111	arg1	Delivery					70:77	Delivery	70:77	Delivery	70:77	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	3	6	theme	mesoporous	659:668	arg1	silica					670:675	mesoporous silica	659:675	mesoporous silica	659:675	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	9	7	theme	activity	1504:1511	arg1	tests					1513:1517	catalase mimetic activity tests	1487:1517	catalase mimetic activity tests	1487:1517	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	5	8	theme	different	907:915	arg1	compositions					917:928	different compositions	907:928	different compositions	907:928	Finally, various MGs at different compositions have been included in alginate beads.					
36614324	10	9	theme	radical	1621:1627	arg1	effect					1640:1645	an extremely good radical scavenging effect	1603:1645	an extremely good radical scavenging effect of curcumin	1603:1657	In addition, an extremely good radical scavenging effect of curcumin has been demonstrated.					
36614324	10	10	theme	curcumin	1650:1657	arg1	effect					1640:1645	an extremely good radical scavenging effect	1603:1645	an extremely good radical scavenging effect of curcumin	1603:1657	In addition, an extremely good radical scavenging effect of curcumin has been demonstrated.					
36614324	5	11	from	compositions	917:928	arg1	MGs					900:902	various MGs	892:902	various MGs at different compositions	892:928	Finally, various MGs at different compositions have been included in alginate beads.					
36614324	11	12	theme	enzymatic-like	1731:1744	arg1	activity					1746:1753	an enzymatic-like activity	1728:1753	an enzymatic-like activity	1728:1753	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	8	13	theme	synergic	1420:1427	arg1	effect					1429:1434	a synergic effect	1418:1434	a synergic effect of cerium and curcumin	1418:1457	For all beads obtained, a curcumin release sufficient to achieve the antioxidant threshold has been reached, and a synergic effect of cerium and curcumin is observed.					
36614324	6	14	theme	beads	1170:1174	arg1	curcumin					1140:1147	curcumin	1140:1147	curcumin	1140:1147	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	6	14	theme	beads	1170:1174	arg1	part					1158:1161	both part	1153:1161	part	1158:1161	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	6	14	theme	beads	1170:1174	arg1	Ce3+/Ce4+					1126:1134	Ce3+/Ce4+	1126:1134	Ce3+/Ce4+	1126:1134	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	6	15	theme	In	968:969	arg1	studies					977:983	In vitro studies	968:983	In vitro studies	968:983	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	5	16	theme	various	892:898	arg1	MGs					900:902	various MGs	892:902	various MGs at different compositions	892:928	Finally, various MGs at different compositions have been included in alginate beads.					
36614324	4	17	theme	curcumin	873:880	arg1	curcumin					873:880	curcumin	873:880	curcumin	873:880	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	4	17	theme	curcumin	873:880	arg1	%					868:868	4 to 6%	862:868	4 to 6% of curcumin	862:880	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	8	18	theme	cerium	1439:1444	arg1	effect					1429:1434	a synergic effect	1418:1434	a synergic effect of cerium and curcumin	1418:1457	For all beads obtained, a curcumin release sufficient to achieve the antioxidant threshold has been reached, and a synergic effect of cerium and curcumin is observed.					
36614324	9	19	dep	Ce3+/Ce4+	1579:1587	arg1	couple					1572:1577	couple	1572:1577	couple	1572:1577	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	0	20	theme	Alginate	0:7	arg1	Beads					9:13	Alginate Beads	0:13	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin	0:67	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	6	21	theme	hybrid	1003:1008	arg1	materials					1010:1018	these hybrid materials	997:1018	these hybrid materials	997:1018	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	2	22	theme	due	371:373	arg1	candidate					361:369	an interesting candidate	346:369	an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	346:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	2	22	theme	due	371:373	arg1	curcumin					328:335	curcumin	328:335	curcumin	328:335	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	3	23	theme	related	508:514	arg1	problem					500:506	the major problem	490:506	the major problem related to its use	490:525	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	23	theme	related	508:514	arg1	bioavailability					544:558	its poor oral bioavailability	530:558	its poor oral bioavailability	530:558	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	9	24	theme	Ce3+/Ce4+	1579:1587	arg1	activity					1556:1563	the well-known catalytic activity	1531:1563	the well-known catalytic activity of the couple Ce3+/Ce4+	1531:1587	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	8	25	theme	curcumin	1450:1457	arg1	effect					1429:1434	a synergic effect	1418:1434	a synergic effect of cerium and curcumin	1418:1457	For all beads obtained, a curcumin release sufficient to achieve the antioxidant threshold has been reached, and a synergic effect of cerium and curcumin is observed.					
36614324	3	26	theme	oral	539:542	arg1	problem					500:506	the major problem	490:506	the major problem related to its use	490:525	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	26	theme	oral	539:542	arg1	bioavailability					544:558	its poor oral bioavailability	530:558	its poor oral bioavailability	530:558	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	11	27	theme	drug	1771:1774	arg1	systems					1785:1791	drug delivery systems	1771:1791	drug delivery systems for curcumin-targeted dosing	1771:1820	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	11	27	theme	drug	1771:1774	arg1	systems					1703:1709	these systems	1697:1709	these systems	1697:1709	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	2	28	theme	anti-tumor	424:433	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	1	29	theme	major	257:261	arg1	role					263:266	a major role	255:266	a major role	255:266	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	4	30	theme	various	692:698	arg1	systems					700:706	various systems	692:706	various systems	692:706	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	2	31	theme	interesting	349:359	arg1	candidate					361:369	an interesting candidate	346:369	an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	346:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	2	31	theme	interesting	349:359	arg1	curcumin					328:335	curcumin	328:335	curcumin	328:335	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	0	32	theme	Cerium-Doped	26:37	arg1	Mesoporous					39:48	Cerium-Doped Mesoporous Glass and Curcumin	26:67	Mesoporous	39:48	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	5	33	theme	alginate	952:959	arg1	beads					961:965	alginate beads	952:965	alginate beads	952:965	Finally, various MGs at different compositions have been included in alginate beads.					
36614324	0	34	dep	Delivery	70:77	arg1	Beads					9:13	Alginate Beads	0:13	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin	0:67	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	2	35	theme	anti-inflammatory	405:421	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	6	36	theme	synergic	1091:1098	arg1	effect					1100:1105	a synergic effect	1089:1105	a synergic effect	1089:1105	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	3	37	theme	poor	534:537	arg1	problem					500:506	the major problem	490:506	the major problem related to its use	490:525	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	37	theme	poor	534:537	arg1	bioavailability					544:558	its poor oral bioavailability	530:558	its poor oral bioavailability	530:558	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	2	38	theme	antioxidant	392:402	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	2	39	theme	anti-infection	450:463	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	8	40	dep	curcumin	1331:1338	arg1	release					1340:1346	release	1340:1346	release sufficient to achieve the antioxidant threshold	1340:1394	For all beads obtained, a curcumin release sufficient to achieve the antioxidant threshold has been reached, and a synergic effect of cerium and curcumin is observed.					
36614324	11	41	theme	curcumin-targeted	1797:1813	arg1	dosing					1815:1820	curcumin-targeted dosing	1797:1820	curcumin-targeted dosing	1797:1820	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	11	42	theme	delivery	1776:1783	arg1	systems					1785:1791	drug delivery systems	1771:1791	drug delivery systems for curcumin-targeted dosing	1771:1820	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	11	42	theme	delivery	1776:1783	arg1	systems					1703:1709	these systems	1697:1709	these systems	1697:1709	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	2	43	theme	versatile	382:390	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	1	44	theme	aberrant	281:288	arg1	homeostasis					297:307	aberrant cancer homeostasis	281:307	aberrant cancer homeostasis	281:307	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	9	45	theme	mimetic	1496:1502	arg1	tests					1513:1517	catalase mimetic activity tests	1487:1517	catalase mimetic activity tests	1487:1517	Moreover, from catalase mimetic activity tests, we confirm the well-known catalytic activity of the couple Ce3+/Ce4+.					
36614324	2	46	from	candidate	361:369	arg1	scenario					318:325	this scenario	313:325	this scenario	313:325	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	1	47	theme	homeostatic	202:212	arg1	errors					214:219	homeostatic errors	202:219	homeostatic errors	202:219	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	1	48	theme	cancer	290:295	arg1	homeostasis					297:307	aberrant cancer homeostasis	281:307	aberrant cancer homeostasis	281:307	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	3	49	theme	small	608:612	arg1	particles					614:622	small particles	608:622	small particles	608:622	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	49	theme	small	608:612	arg1	beads					642:646	hydrogel beads	633:646	hydrogel beads containing mesoporous silica	633:675	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	4	50	theme	cerium-containing	778:794	arg1	MGs					796:798	cerium-containing MGs	778:798	cerium-containing MGs	778:798	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	7	51	theme	swelling	1182:1189	arg1	tests					1191:1195	swelling tests	1182:1195	swelling tests	1182:1195	From swelling tests, it is possible to confirm a controlled curcumin release compartmentalized into the gastrointestinal tract.					
36614324	2	52	theme	anti-HIV	436:443	arg1	properties					465:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties	378:474	In this scenario, curcumin could be an interesting candidate due to its versatile antioxidant, anti-inflammatory, anti-tumor, anti-HIV, and anti-infection properties.					
36614324	3	53	theme	hydrogel	633:640	arg1	beads					642:646	hydrogel beads	633:646	hydrogel beads containing mesoporous silica	633:675	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	0	54	dep	Mesoporous	39:48	arg1	Glass					50:54	Glass	50:54	Glass	50:54	Alginate Beads Containing Cerium-Doped Mesoporous Glass and Curcumin: Delivery and Stabilization of Therapeutics.					
36614324	6	55	theme	effective	1049:1057	arg1	delivery					1059:1066	effective delivery	1049:1066	effective delivery	1049:1066	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	7	56	from	tests	1191:1195	arg1	possible					1204:1211	possible	1204:1211	possible	1204:1211	From swelling tests, it is possible to confirm a controlled curcumin release compartmentalized into the gastrointestinal tract.					
36614324	8	57	theme	antioxidant	1374:1384	arg1	threshold					1386:1394	the antioxidant threshold	1370:1394	the antioxidant threshold	1370:1394	For all beads obtained, a curcumin release sufficient to achieve the antioxidant threshold has been reached, and a synergic effect of cerium and curcumin is observed.					
36614324	4	58	theme	silica	756:761	arg1	glasses					763:769	mesoporous silica glasses	745:769	mesoporous silica glasses (MGs)	745:775	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	4	58	theme	silica	756:761	arg1	MGs					772:774	MGs	772:774	MGs	772:774	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	1	59	theme	leading	126:132	arg1	cause					134:138	a leading cause	124:138	a leading cause of death worldwide	124:157	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	1	59	theme	leading	126:132	arg1	Cancer					114:119	Cancer	114:119	Cancer	114:119	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	6	60	theme	curcumin	1071:1078	arg1	stabilization					1031:1043	stabilization	1031:1043	stabilization	1031:1043	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	6	60	theme	curcumin	1071:1078	arg1	delivery					1059:1066	effective delivery	1049:1066	effective delivery	1049:1066	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	10	61	theme	good	1616:1619	arg1	effect					1640:1645	an extremely good radical scavenging effect	1603:1645	an extremely good radical scavenging effect of curcumin	1603:1657	In addition, an extremely good radical scavenging effect of curcumin has been demonstrated.					
36614324	6	62	dep	In	968:969	arg1	vitro					971:975	vitro	971:975	vitro	971:975	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	10	63	theme	scavenging	1629:1638	arg1	effect					1640:1645	an extremely good radical scavenging effect	1603:1645	an extremely good radical scavenging effect of curcumin	1603:1657	In addition, an extremely good radical scavenging effect of curcumin has been demonstrated.					
36614324	4	64	theme	mesoporous	745:754	arg1	glasses					763:769	mesoporous silica glasses	745:769	mesoporous silica glasses (MGs)	745:775	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	4	64	theme	mesoporous	745:754	arg1	MGs					772:774	MGs	772:774	MGs	772:774	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	3	65	contain	containing	648:657	arg2	silica					670:675	mesoporous silica	659:675	mesoporous silica	659:675	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	3	65	contain	containing	648:657	arg1	beads					642:646	hydrogel beads	633:646	hydrogel beads containing mesoporous silica	633:675	Nonetheless, the major problem related to its use is its poor oral bioavailability, which can be overcome by encapsulating it into small particles, such as hydrogel beads containing mesoporous silica.					
36614324	11	66	used	used	1763:1766	arg2	systems					1703:1709	these systems	1697:1709	these systems	1697:1709	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	11	66	used	used	1763:1766	arg2	systems					1785:1791	drug delivery systems	1771:1791	drug delivery systems for curcumin-targeted dosing	1771:1820	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	7	67	theme	curcumin	1237:1244	arg1	release					1246:1252	a controlled curcumin release	1224:1252	a controlled curcumin release compartmentalized into the gastrointestinal tract	1224:1302	From swelling tests, it is possible to confirm a controlled curcumin release compartmentalized into the gastrointestinal tract.					
36614324	4	68	dep	6	867:867	arg1	to					864:865	to	864:865	to	864:865	In this work, various systems have been synthesized: starting from mesoporous silica glasses (MGs), cerium-containing MGs have been produced; then, these systems have been loaded with 4 to 6% of curcumin.					
36614324	7	69	theme	controlled	1226:1235	arg1	release					1246:1252	a controlled curcumin release	1224:1252	a controlled curcumin release compartmentalized into the gastrointestinal tract	1224:1302	From swelling tests, it is possible to confirm a controlled curcumin release compartmentalized into the gastrointestinal tract.					
36614324	11	70	theme	able	1712:1715	arg1	systems					1785:1791	drug delivery systems	1771:1791	drug delivery systems for curcumin-targeted dosing	1771:1820	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	11	70	theme	able	1712:1715	arg1	systems					1703:1709	these systems	1697:1709	these systems	1697:1709	In conclusion, these systems, able to promote an enzymatic-like activity, can be used as drug delivery systems for curcumin-targeted dosing.					
36614324	6	71	dep	part	1158:1161	arg1	both					1153:1156	both	1153:1156	both	1153:1156	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	6	72	dep	stabilization	1031:1043	arg1	the					1027:1029	the	1027:1029	the	1027:1029	In vitro studies showed that these hybrid materials enable the stabilization and effective delivery of curcumin and that a synergic effect can be achieved if Ce3+/Ce4+ and curcumin are both part of the beads.					
36614324	1	73	theme	death	143:147	arg1	worldwide					149:157	death worldwide	143:157	death worldwide	143:157	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36614324	7	74	theme	gastrointestinal	1281:1296	arg1	tract					1298:1302	the gastrointestinal tract	1277:1302	the gastrointestinal tract	1277:1302	From swelling tests, it is possible to confirm a controlled curcumin release compartmentalized into the gastrointestinal tract.					
36614324	1	75	theme	reactive	226:233	arg1	species					242:248	reactive oxygen species	226:248	reactive oxygen species	226:248	Cancer is a leading cause of death worldwide, its genesis and progression are caused by homeostatic errors, and reactive oxygen species play a major role in promoting aberrant cancer homeostasis.					
36934823	6	0	theme	gas	1042:1044	arg1	detection					1046:1054	NH3 gas detection	1038:1054	NH3 gas detection	1038:1054	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	7	1	from	50 ppm	1154:1159	arg1	range					1112:1116	the linear range	1101:1116	the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm	1101:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	7	1	from	50 ppm	1154:1159	arg1	concentration					1129:1141	NH3 gas concentration	1121:1141	NH3 gas concentration	1121:1141	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	7	2	theme	linear	1105:1110	arg1	range					1112:1116	the linear range	1101:1116	the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm	1101:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	4	3	theme	film	607:610	arg1	layer					612:616	(A)film layer	604:616	(A)film layer	604:616	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	6	4	theme	NH3	1038:1040	arg1	detection					1046:1054	NH3 gas detection	1038:1054	NH3 gas detection	1038:1054	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	7	5	theme	NH3	1121:1123	arg1	concentration					1129:1141	NH3 gas concentration	1121:1141	NH3 gas concentration	1121:1141	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	5	6	theme	dual	751:754	arg1	interactions					756:767	dual interactions	751:767	dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time	751:843	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	9	7	theme	NH3	1519:1521	arg1	field					1534:1538	the NH3 gas sensor field	1515:1538	the NH3 gas sensor field	1515:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	8	8	theme	Sensor	1259:1264	arg1	performances					1266:1277	Sensor performances	1259:1277	Sensor performances	1259:1277	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	0	9	theme	Behnken	87:93	arg1	design					95:100	Box Behnken design	83:100	Box Behnken design	83:100	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	3	10	theme	Box-Behnken	548:558	arg1	Design					560:565	Box-Behnken Design	548:565	Box-Behnken Design	548:565	The NH3 gas detection optimization was evaluated using Box-Behnken Design.					
36934823	0	11	dep	grafted	33:39	arg1	polyaniline					41:51	polyaniline	41:51	grafted polyaniline for ammonia gas detection via Box Behnken design	33:100	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	8	12	theme	NH3	1336:1338	arg1	gas					1340:1342	NH3 gas	1336:1342	NH3 gas	1336:1342	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	7	13	theme	linear	1182:1187	arg1	curve					1201:1205	a linear calibration curve	1180:1205	a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm	1180:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	0	14	theme	Box	83:85	arg1	design					95:100	Box Behnken design	83:100	Box Behnken design	83:100	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	9	15	theme	sensor	1527:1532	arg1	field					1534:1538	the NH3 gas sensor field	1515:1538	the NH3 gas sensor field	1515:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	7	16	theme	calibration	1189:1199	arg1	curve					1201:1205	a linear calibration curve	1180:1205	a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm	1180:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	5	17	theme	significant	859:869	arg1	factors					871:877	the significant factors	855:877	the significant factors	855:877	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	9	18	theme	economical	1494:1503	arg1	Ch-g-PANI					1462:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	9	18	theme	economical	1494:1503	arg1	sensor					1505:1510	an inexpensive and economical sensor	1475:1510	an inexpensive and economical sensor in the NH3 gas sensor field	1475:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	2	19	theme	Scanning	328:335	arg1	microscopy					346:355	Scanning electron microscopy	328:355	Scanning electron microscopy (SEM)	328:361	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	2	19	theme	Scanning	328:335	arg1	SEM					358:360	SEM	358:360	SEM	358:360	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	5	20	theme	contact	796:802	arg1	time					804:807	(C)contact time	793:807	(C)contact time	793:807	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	8	21	theme	interfering	1361:1371	arg1	gases					1373:1377	the common interfering gases	1350:1377	the common interfering gases	1350:1377	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	4	22	theme	physical	579:586	arg1	%					630:630	(B)loading %	619:630	(B)loading %	619:630	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	4	22	theme	physical	579:586	arg1	factors					588:594	physical factors	579:594	physical factors such as (A)film layer, (B)loading %, and (C)contact time	579:651	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	4	22	theme	physical	579:586	arg1	time					648:651	(C)contact time	637:651	(C)contact time	637:651	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	4	22	theme	physical	579:586	arg1	layer					612:616	(A)film layer	604:616	(A)film layer	604:616	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	6	23	theme	highest	931:937	arg1	sensitivity					939:949	the highest sensitivity	927:949	the highest sensitivity	927:949	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	4	24	theme	loading	622:628	arg1	%					630:630	(B)loading %	619:630	(B)loading %	619:630	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	8	25	theme	common	1354:1359	arg1	gases					1373:1377	the common interfering gases	1350:1377	the common interfering gases	1350:1377	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	4	26	dep	time	648:651	arg1	C					638:638	C	638:638	C	638:638	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	2	27	theme	elemental	364:372	arg1	mapping					374:380	elemental mapping	364:380	elemental mapping	364:380	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	4	28	theme	variance	709:716	arg1	analysis					697:704	the analysis	693:704	the analysis of variance (ANOVA)	693:724	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	5	29	theme	film	780:783	arg1	layer					785:789	(A)film layer	777:789	(A)film layer	777:789	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	6	30	theme	contact	1013:1019	arg1	10 min					1027:1032	10 min	1027:1032	10 min	1027:1032	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	6	30	theme	contact	1013:1019	arg1	time					1021:1024	(C)contact time (10 min)	1010:1033	(C)contact time (10 min)	1010:1033	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	0	31	theme	fungal	19:24	arg1	chitin					26:31	fungal chitin	19:31	fungal chitin	19:31	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	2	32	dep	transform	429:437	arg1	infrared					439:446	infrared	439:446	transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy	429:490	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	7	33	dep	50 ppm	1154:1159	arg1	to					1151:1152	to	1151:1152	to	1151:1152	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	1	34	theme	wild	159:162	arg1	mushrooms					164:172	wild mushrooms	159:172	wild mushrooms	159:172	In this work, chitin (Ch) was chemically extracted from wild mushrooms and then grafted to polyaniline (PANI) to form a composite (Ch-g-PANI) to detect ammonia (NH3) gas.					
36934823	7	35	theme	optimized	1067:1075	arg1	Ch-g-PANI					1077:1085	the optimized Ch-g-PANI	1063:1085	the optimized Ch-g-PANI	1063:1085	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	6	36	dep	time	1021:1024	arg1	C					1011:1011	C	1011:1011	C	1011:1011	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	2	37	dep	Fourier	421:427	arg1	transform					429:437	transform	429:437	transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy	429:490	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	5	38	theme	contact	832:838	arg1	time					840:843	(C)contact time	829:843	(C)contact time	829:843	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	4	39	dep	layer	612:616	arg1	A					605:605	A	605:605	A	605:605	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	5	40	theme	loading	817:823	arg1	%					825:825	(B)loading %	814:825	(B)loading %	814:825	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	9	41	theme	mushroom-sourced	1445:1460	arg1	Ch-g-PANI					1462:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	9	41	theme	mushroom-sourced	1445:1460	arg1	sensor					1505:1510	an inexpensive and economical sensor	1475:1510	an inexpensive and economical sensor in the NH3 gas sensor field	1475:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	3	42	theme	detection	505:513	arg1	optimization					515:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization was evaluated using Box-Behnken Design.					
36934823	5	43	dep	time	804:807	arg1	C					794:794	C	794:794	C	794:794	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	0	44	theme	chitin	26:31	arg1	optimization					3:14	An optimization	0:14	An optimization of fungal chitin	0:31	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	7	45	theme	15.03 ppm	1248:1256	arg1	limit					1239:1243	a detection limit	1227:1243	a detection limit of 15.03 ppm	1227:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	7	45	theme	15.03 ppm	1248:1256	arg1	R2 = 0.994					1212:1221	R2 = 0.994	1212:1221	R2 = 0.994	1212:1221	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	7	46	from	range	1112:1116	arg1	50 ppm					1154:1159	50 ppm	1154:1159	50 ppm	1154:1159	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	2	47	theme	electron	337:344	arg1	microscopy					346:355	Scanning electron microscopy	328:355	Scanning electron microscopy (SEM)	328:361	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	2	47	theme	electron	337:344	arg1	SEM					358:360	SEM	358:360	SEM	358:360	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	2	48	theme	thermogravimetric	383:399	arg1	TGA					411:413	TGA	411:413	TGA	411:413	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	2	48	theme	thermogravimetric	383:399	arg1	analysis					401:408	thermogravimetric analysis	383:408	thermogravimetric analysis (TGA)	383:414	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	9	49	from	sensor	1505:1510	arg1	field					1534:1538	the NH3 gas sensor field	1515:1538	the NH3 gas sensor field	1515:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	3	50	theme	NH3	497:499	arg1	optimization					515:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization was evaluated using Box-Behnken Design.					
36934823	6	51	theme	significant	901:911	arg1	interactions					913:924	these significant interactions	895:924	these significant interactions	895:924	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	7	52	theme	gas	1125:1127	arg1	concentration					1129:1141	NH3 gas concentration	1121:1141	NH3 gas concentration	1121:1141	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	6	53	dep	loading	991:997	arg1	B					989:989	B	989:989	B	989:989	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	8	54	contain	possess	1307:1313	arg1	films					1301:1305	Ch-g-PANI films	1291:1305	Ch-g-PANI films	1291:1305	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	8	54	contain	possess	1307:1313	arg2	selectivity					1320:1330	high selectivity	1315:1330	high selectivity for NH3 gas among the common interfering gases	1315:1377	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	3	55	theme	gas	501:503	arg1	optimization					515:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization	493:526	The NH3 gas detection optimization was evaluated using Box-Behnken Design.					
36934823	7	56	with	curve	1201:1205	arg1	limit					1239:1243	a detection limit	1227:1243	a detection limit of 15.03 ppm	1227:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	7	56	with	curve	1201:1205	arg1	R2 = 0.994					1212:1221	R2 = 0.994	1212:1221	R2 = 0.994	1212:1221	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	4	57	dep	%	630:630	arg1	B					620:620	B	620:620	B	620:620	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	9	58	theme	inexpensive	1478:1488	arg1	Ch-g-PANI					1462:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	9	58	theme	inexpensive	1478:1488	arg1	sensor					1505:1510	an inexpensive and economical sensor	1475:1510	an inexpensive and economical sensor in the NH3 gas sensor field	1475:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	1	59	theme	ammonia	255:261	arg1	gas					269:271	ammonia (NH3) gas	255:271	ammonia (NH3) gas	255:271	In this work, chitin (Ch) was chemically extracted from wild mushrooms and then grafted to polyaniline (PANI) to form a composite (Ch-g-PANI) to detect ammonia (NH3) gas.					
36934823	6	60	theme	film	972:975	arg1	3					984:984	3	984:984	3	984:984	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	6	60	theme	film	972:975	arg1	layer					977:981	(A)film layer	969:981	(A)film layer (3)	969:985	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	8	61	theme	Ch-g-PANI	1291:1299	arg1	films					1301:1305	Ch-g-PANI films	1291:1305	Ch-g-PANI films	1291:1305	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	2	62	theme	UV-Vis	472:477	arg1	spectroscopy					479:490	UV-Vis spectroscopy	472:490	UV-Vis spectroscopy	472:490	The Ch-g-PANI was comprehensively characterized using Scanning electron microscopy (SEM), elemental mapping, thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) and UV-Vis spectroscopy.					
36934823	4	63	theme	contact	640:646	arg1	time					648:651	(C)contact time	637:651	(C)contact time	637:651	Typically, physical factors such as (A)film layer, (B)loading %, and (C)contact time were investigated and validated through the analysis of variance (ANOVA).					
36934823	8	64	theme	high	1315:1318	arg1	selectivity					1320:1330	high selectivity	1315:1330	high selectivity for NH3 gas among the common interfering gases	1315:1377	Sensor performances showed that Ch-g-PANI films possess high selectivity for NH3 gas among the common interfering gases and the film can be reused for up to 6 cycles.					
36934823	7	65	theme	detection	1229:1237	arg1	limit					1239:1243	a detection limit	1227:1243	a detection limit of 15.03 ppm	1227:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	0	66	theme	gas	65:67	arg1	detection					69:77	ammonia gas detection	57:77	ammonia gas detection	57:77	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	9	67	theme	gas	1523:1525	arg1	field					1534:1538	the NH3 gas sensor field	1515:1538	the NH3 gas sensor field	1515:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	5	68	dep	layer	785:789	arg1	A					778:778	A	778:778	A	778:778	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	5	69	dep	%	825:825	arg1	B					815:815	B	815:815	B	815:815	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
36934823	0	70	theme	ammonia	57:63	arg1	detection					69:77	ammonia gas detection	57:77	ammonia gas detection	57:77	An optimization of fungal chitin grafted polyaniline for ammonia gas detection via Box Behnken design.					
36934823	7	71	theme	concentration	1129:1141	arg1	range					1112:1116	the linear range	1101:1116	the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm	1101:1256	Then, the optimized Ch-g-PANI was tested in the linear range of NH3 gas concentration from 10 to 50 ppm, which resulted in a linear calibration curve with R2 = 0.994 and a detection limit of 15.03 ppm.					
36934823	9	72	theme	new	1441:1443	arg1	Ch-g-PANI					1462:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	the new mushroom-sourced Ch-g-PANI	1437:1470	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	9	72	theme	new	1441:1443	arg1	sensor					1505:1510	an inexpensive and economical sensor	1475:1510	an inexpensive and economical sensor in the NH3 gas sensor field	1475:1538	Therefore, the new mushroom-sourced Ch-g-PANI is an inexpensive and economical sensor in the NH3 gas sensor field.					
36934823	6	73	dep	layer	977:981	arg1	A					970:970	A	970:970	A	970:970	By considering these significant interactions, the highest sensitivity was obtained when (A)film layer (3), (B)loading (5 %), and (C)contact time (10 min) in NH3 gas detection.					
36934823	5	74	dep	time	840:843	arg1	C					830:830	C	830:830	C	830:830	The ANOVA revealed that dual interactions between (A)film layer - (C)contact time, and (B)loading % - (C)contact time are among the significant factors.					
35176325	0	0	theme	dextran	102:108	arg1	sulfate					110:116	dextran sulfate	102:116	dextran sulfate	102:116	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	4	1	theme	microbiota	809:818	arg1	fermentation					789:800	fermentation	789:800	fermentation of gut microbiota	789:818	In addition, Ax-Alg can well tolerate the conditions in the mouth, stomach and small intestine and reach the colon where Ax was released due to fermentation of gut microbiota.					
35176325	7	2	theme	better	1202:1207	arg1	effect					1209:1214	better effect	1202:1214	better effect	1202:1214	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	6	3	with	correlation	1154:1164	arg1	colitis					1182:1188	ulcerative colitis	1171:1188	ulcerative colitis	1171:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	8	4	from	application	1387:1397	arg1	foods					1440:1444	the foods	1436:1444	the foods	1436:1444	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	8	5	theme	colon	1463:1467	arg1	diseases					1469:1476	colon diseases	1463:1476	colon diseases	1463:1476	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	4	6	theme	gut	805:807	arg1	microbiota					809:818	gut microbiota	805:818	gut microbiota	805:818	In addition, Ax-Alg can well tolerate the conditions in the mouth, stomach and small intestine and reach the colon where Ax was released due to fermentation of gut microbiota.					
35176325	3	7	dep	maintain	563:570	arg1	heat					630:633	heat	630:633	heat	630:633	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	3	7	dep	maintain	563:570	arg1	pH					626:627	pH	626:627	pH	626:627	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	3	7	dep	maintain	563:570	arg1	ion					639:641	ion	639:641	ion	639:641	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	0	8	from	Fabrication	0:10	arg1	sulfate					110:116	dextran sulfate	102:116	dextran sulfate	102:116	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	6	9	theme	Bacteroidetes	1114:1126	arg1	members					1128:1134	Bacteroidetes members	1114:1134	Bacteroidetes members that had positive correlation with ulcerative colitis	1114:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	1	10	dep	Astaxanthin	161:171	arg1	Ax					174:175	Ax	174:175	Ax	174:175	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	5	11	theme	sodium-induced	880:893	arg1	colitis					895:901	dextran sulfate sodium-induced colitis	864:901	dextran sulfate sodium-induced colitis	864:901	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	3	12	dep	in	524:525	arg1	vitro					527:531	vitro	527:531	vitro	527:531	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	3	13	theme	in	524:525	arg1	models					533:538	The in vitro models	520:538	The in vitro models	520:538	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	2	14	theme	high-pressure	409:421	arg1	spraying					423:430	high-pressure spraying	409:430	high-pressure spraying	409:430	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	0	15	theme	ulcerative	133:142	arg1	colitis					144:150	ulcerative colitis	133:150	ulcerative colitis in mice	133:158	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	1	16	with	Astaxanthin	161:171	arg1	activity					204:211	a strong antioxidant activity	183:211	a strong antioxidant activity	183:211	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	4	17	theme	small	724:728	arg1	conditions					687:696	the conditions	683:696	the conditions in the mouth	683:709	In addition, Ax-Alg can well tolerate the conditions in the mouth, stomach and small intestine and reach the colon where Ax was released due to fermentation of gut microbiota.					
35176325	4	17	theme	small	724:728	arg1	intestine					730:738	small intestine	724:738	small intestine	724:738	In addition, Ax-Alg can well tolerate the conditions in the mouth, stomach and small intestine and reach the colon where Ax was released due to fermentation of gut microbiota.					
35176325	8	18	theme	system	1426:1431	arg1	application					1387:1397	the application	1383:1397	the application of colon-targeted delivery system in the foods	1383:1444	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	8	18	theme	system	1426:1431	arg1	treatment					1450:1458	treatment	1450:1458	treatment of colon diseases	1450:1476	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	1	19	theme	strong	185:190	arg1	activity					204:211	a strong antioxidant activity	183:211	a strong antioxidant activity	183:211	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	8	20	theme	diseases	1469:1476	arg1	application					1387:1397	the application	1383:1397	the application of colon-targeted delivery system in the foods	1383:1444	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	8	20	theme	diseases	1469:1476	arg1	treatment					1450:1458	treatment	1450:1458	treatment of colon diseases	1450:1476	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	1	21	theme	antioxidant	192:202	arg1	activity					204:211	a strong antioxidant activity	183:211	a strong antioxidant activity	183:211	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	5	22	theme	Mice	821:824	arg1	experiment					826:835	Mice experiment	821:835	Mice experiment	821:835	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	0	23	theme	colon-targeted	36:49	arg1	microspheres					60:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	6	24	theme	other	1024:1028	arg1	hand					1030:1033	the other hand	1020:1033	the other hand	1020:1033	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	8	25	theme	colon-targeted	1402:1415	arg1	system					1426:1431	colon-targeted delivery system	1402:1431	colon-targeted delivery system	1402:1431	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	7	26	theme	Ax	1336:1337	arg1	effect					1326:1331	the synergistic effect	1310:1331	the synergistic effect of Ax and alginate	1310:1350	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	0	27	theme	astaxanthin-enriched	15:34	arg1	microspheres					60:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	1	28	theme	unsaturated	289:299	arg1	structure					301:309	its highly unsaturated structure	278:309	its highly unsaturated structure	278:309	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	5	29	theme	disease	927:933	arg1	index					944:948	disease activity index	927:948	disease activity index	927:948	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	5	30	theme	weight	914:919	arg1	loss					921:924	weight loss	914:924	weight loss	914:924	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	3	31	from	integrity	587:595	arg1	conditions					614:623	the different conditions	600:623	the different conditions	600:623	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	2	32	theme	ionic	436:440	arg1	gelation					442:449	ionic gelation	436:449	ionic gelation	436:449	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	0	33	theme	microspheres	60:71	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres	0:71	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	0	33	theme	microspheres	60:71	arg1	effect					92:97	its beneficial effect	77:97	its beneficial effect on dextran sulfate	77:116	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	5	34	theme	dextran	864:870	arg1	sulfate					872:878	dextran sulfate	864:878	dextran sulfate sodium-induced colitis	864:901	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	2	35	from	range	485:489	arg1	diameter					510:517	a diameter	508:517	a diameter	508:517	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	6	36	theme	positive	1145:1152	arg1	correlation					1154:1164	positive correlation	1145:1164	positive correlation with ulcerative colitis	1145:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	0	37	theme	alginate	51:58	arg1	microspheres					60:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	astaxanthin-enriched colon-targeted alginate microspheres	15:71	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	0	38	from	effect	92:97	arg1	sulfate					110:116	dextran sulfate	102:116	dextran sulfate	102:116	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	7	39	theme	alginate	1343:1350	arg1	effect					1326:1331	the synergistic effect	1310:1331	the synergistic effect of Ax and alginate	1310:1350	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	1	40	theme	human	230:234	arg1	health					236:241	human health	230:241	human health	230:241	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	1	41	theme	poor	315:318	arg1	water-solubility					320:335	poor water-solubility	315:335	poor water-solubility	315:335	Astaxanthin (Ax) with a strong antioxidant activity is beneficial to human health, but its application is limited by its highly unsaturated structure and poor water-solubility.					
35176325	2	42	theme	0.5-3.2 μm	494:503	arg1	range					485:489	the range	481:489	the range of 0.5-3.2 μm	481:503	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	6	43	theme	microbiota	1061:1070	arg1	composition					1072:1082	the gut microbiota composition	1053:1082	the gut microbiota composition	1053:1082	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	2	44	theme	alginate	365:372	arg1	Ax-Alg					385:390	Ax-Alg	385:390	Ax-Alg	385:390	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	2	44	theme	alginate	365:372	arg1	particles					374:382	Ax-enriched colon targeted alginate particles	338:382	Ax-enriched colon targeted alginate particles (Ax-Alg)	338:391	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	0	45	from	colitis	144:150	arg1	mice					155:158	mice	155:158	mice	155:158	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	3	46	theme	structural	576:585	arg1	integrity					587:595	the structural integrity	572:595	the structural integrity in the different conditions	572:623	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	7	47	theme	ulcerative	1236:1245	arg1	colitis					1247:1253	ulcerative colitis	1236:1253	ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate	1236:1350	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	2	48	theme	targeted	356:363	arg1	Ax-Alg					385:390	Ax-Alg	385:390	Ax-Alg	385:390	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	2	48	theme	targeted	356:363	arg1	particles					374:382	Ax-enriched colon targeted alginate particles	338:382	Ax-enriched colon targeted alginate particles (Ax-Alg)	338:391	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	4	49	from	conditions	687:696	arg1	mouth					705:709	the mouth	701:709	the mouth	701:709	In addition, Ax-Alg can well tolerate the conditions in the mouth, stomach and small intestine and reach the colon where Ax was released due to fermentation of gut microbiota.					
35176325	5	50	theme	mucosal	959:965	arg1	integrity					967:975	colonic mucosal integrity	951:975	colonic mucosal integrity	951:975	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	5	51	theme	oxidative	999:1007	arg1	damage					1009:1014	oxidative damage	999:1014	oxidative damage	999:1014	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	6	52	theme	ulcerative	1171:1180	arg1	colitis					1182:1188	ulcerative colitis	1171:1188	ulcerative colitis	1171:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	2	53	theme	colon	350:354	arg1	Ax-Alg					385:390	Ax-Alg	385:390	Ax-Alg	385:390	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	2	53	theme	colon	350:354	arg1	particles					374:382	Ax-enriched colon targeted alginate particles	338:382	Ax-enriched colon targeted alginate particles (Ax-Alg)	338:391	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	6	54	theme	gut	1057:1059	arg1	composition					1072:1082	the gut microbiota composition	1053:1082	the gut microbiota composition	1053:1082	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	5	55	theme	activity	935:942	arg1	index					944:948	disease activity index	927:948	disease activity index	927:948	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	7	56	theme	colitis	1247:1253	arg1	treatment					1223:1231	the treatment	1219:1231	the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate	1219:1350	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	7	57	theme	synergistic	1314:1324	arg1	effect					1326:1331	the synergistic effect	1310:1331	the synergistic effect of Ax and alginate	1310:1350	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	8	58	from	treatment	1450:1458	arg1	foods					1440:1444	the foods	1436:1444	the foods	1436:1444	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	2	59	theme	Ax-enriched	338:348	arg1	Ax-Alg					385:390	Ax-Alg	385:390	Ax-Alg	385:390	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	2	59	theme	Ax-enriched	338:348	arg1	particles					374:382	Ax-enriched colon targeted alginate particles	338:382	Ax-enriched colon targeted alginate particles (Ax-Alg)	338:391	Ax-enriched colon targeted alginate particles (Ax-Alg) was prepared by high-pressure spraying and ionic gelation, and most of particles was in the range of 0.5-3.2 μm in a diameter.					
35176325	5	60	theme	sulfate	872:878	arg1	colitis					895:901	dextran sulfate sodium-induced colitis	864:901	dextran sulfate sodium-induced colitis	864:901	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	8	61	theme	delivery	1417:1424	arg1	system					1426:1431	colon-targeted delivery system	1402:1431	colon-targeted delivery system	1402:1431	This study can be helpful for the application of colon-targeted delivery system in the foods and treatment of colon diseases.					
35176325	7	62	theme	oil-in-water	1260:1271	arg1	emulsion					1273:1280	oil-in-water emulsion	1260:1280	oil-in-water emulsion	1260:1280	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	5	63	theme	colonic	951:957	arg1	integrity					967:975	colonic mucosal integrity	951:975	colonic mucosal integrity	951:975	Mice experiment showed that Ax-Alg reduced dextran sulfate sodium-induced colitis, involving weight loss, disease activity index, colonic mucosal integrity and inflammation, and oxidative damage.					
35176325	6	64	theme	members	1128:1134	arg1	abundances					1100:1109	the abundances	1096:1109	the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis	1096:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	0	65	theme	beneficial	81:90	arg1	effect					92:97	its beneficial effect	77:97	its beneficial effect on dextran sulfate	77:116	Fabrication of astaxanthin-enriched colon-targeted alginate microspheres and its beneficial effect on dextran sulfate sodium-induced ulcerative colitis in mice.					
35176325	3	66	theme	different	604:612	arg1	conditions					614:623	the different conditions	600:623	the different conditions	600:623	The in vitro models showed that Ax-Alg can maintain the structural integrity in the different conditions (pH, heat and ion).					
35176325	7	67	contain	had	1198:1200	arg1	Ax-Alg					1191:1196	Ax-Alg	1191:1196	Ax-Alg	1191:1196	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	7	67	contain	had	1198:1200	arg2	effect					1209:1214	better effect	1202:1214	better effect	1202:1214	Ax-Alg had better effect on the treatment of ulcerative colitis than oil-in-water emulsion, which can be attributed to the synergistic effect of Ax and alginate.					
35176325	6	68	contain	had	1141:1143	arg1	members					1128:1134	Bacteroidetes members	1114:1134	Bacteroidetes members that had positive correlation with ulcerative colitis	1114:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
35176325	6	68	contain	had	1141:1143	arg2	correlation					1154:1164	positive correlation	1145:1164	positive correlation with ulcerative colitis	1145:1188	On the other hand, Ax-Alg regulated the gut microbiota composition and reduced the abundances of Bacteroidetes members that had positive correlation with ulcerative colitis.					
36167100	0	0	theme	oxide	80:84	arg1	nanohybids					86:95	graphene oxide nanohybids	71:95	graphene oxide nanohybids	71:95	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	4	1	theme	AOGO	648:651	arg1	nanohybrids					653:663	AOGO nanohybrids	648:663	AOGO nanohybrids	648:663	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	1	2	theme	metal	158:162	arg1	decontamination					164:178	metal decontamination	158:178	metal decontamination of water using copper {Cu (II)} as a model pollutant	158:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	1	3	theme	model	217:221	arg1	pollutant					223:231	a model pollutant	215:231	a model pollutant	215:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	1	3	theme	model	217:221	arg1	}					210:210	copper {Cu (II)}	195:210	copper {Cu (II)}	195:210	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	0	4	theme	graphene	71:78	arg1	nanohybids					86:95	graphene oxide nanohybids	71:95	graphene oxide nanohybids	71:95	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	6	5	dep	transform	847:855	arg1	infrared					857:864	infrared	857:864	transform infrared spectroscopy (FTIR)	847:884	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	2	6	from	solutions	385:393	arg1	removal					364:370	the Cu (II) removal	352:370	the Cu (II) removal from aqueous solutions	352:393	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	2	7	theme	chitosan	259:266	arg1	beads					250:254	Novel composite beads	234:254	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO)	234:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	4	8	theme	amidoxime	623:631	arg1	groups					633:638	amidoxime groups	623:638	amidoxime groups	623:638	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	9	theme	graphene	562:569	arg1	GO-g-PAN					578:585	GO-g-PAN	578:585	GO-g-PAN	578:585	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	9	theme	graphene	562:569	arg1	oxide					571:575	polyacrylonitrile grafted graphene oxide	536:575	polyacrylonitrile grafted graphene oxide (GO-g-PAN)	536:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	8	10	dep	conditions	1179:1188	arg1	pH					1214:1215	pH	1214:1215	pH	1214:1215	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	10	dep	conditions	1179:1188	arg1	conditions					1179:1188	different conditions	1169:1188	different conditions (initial concentration, pH, and contact time)	1169:1234	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	10	dep	conditions	1179:1188	arg1	concentration					1199:1211	initial concentration	1191:1211	initial concentration	1191:1211	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	10	dep	conditions	1179:1188	arg1	time					1230:1233	contact time	1222:1233	contact time	1222:1233	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	9	11	theme	composite	1275:1283	arg1	beads					1285:1289	composite beads	1275:1289	composite beads	1275:1289	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	2	12	theme	oxide	299:303	arg1	beads					250:254	Novel composite beads	234:254	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO)	234:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	8	13	theme	Cu	1114:1115	arg1	adsorption					1100:1109	The adsorption	1096:1109	The adsorption of Cu (II) onto CP/AOGO composite beads	1096:1149	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	3	14	theme	silanized	478:486	arg1	substrate					503:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	For this purpose, acrylonitrile was first polymerized onto a gamma-irradiated and silanized graphene oxide substrate.					
36167100	2	15	theme	Cu	356:357	arg1	removal					364:370	the Cu (II) removal	352:370	the Cu (II) removal from aqueous solutions	352:393	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	4	16	theme	grafted	554:560	arg1	GO-g-PAN					578:585	GO-g-PAN	578:585	GO-g-PAN	578:585	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	16	theme	grafted	554:560	arg1	oxide					571:575	polyacrylonitrile grafted graphene oxide	536:575	polyacrylonitrile grafted graphene oxide (GO-g-PAN)	536:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	17	theme	polyacrylonitrile	536:552	arg1	GO-g-PAN					578:585	GO-g-PAN	578:585	GO-g-PAN	578:585	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	17	theme	polyacrylonitrile	536:552	arg1	oxide					571:575	polyacrylonitrile grafted graphene oxide	536:575	polyacrylonitrile grafted graphene oxide (GO-g-PAN)	536:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	2	18	theme	composite	240:248	arg1	beads					250:254	Novel composite beads	234:254	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO)	234:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	1	19	theme	water	183:187	arg1	decontamination					164:178	metal decontamination	158:178	metal decontamination of water using copper {Cu (II)} as a model pollutant	158:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	2	20	theme	graphene	290:297	arg1	AOGO					306:309	AOGO	306:309	AOGO	306:309	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	2	20	theme	graphene	290:297	arg1	oxide					299:303	amidoxime grafted graphene oxide	272:303	amidoxime grafted graphene oxide (AOGO)	272:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	6	21	theme	structural	908:917	arg1	changes					919:925	the structural changes	904:925	the structural changes	904:925	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	2	22	theme	grafted	282:288	arg1	AOGO					306:309	AOGO	306:309	AOGO	306:309	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	2	22	theme	grafted	282:288	arg1	oxide					299:303	amidoxime grafted graphene oxide	272:303	amidoxime grafted graphene oxide (AOGO)	272:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	1	23	theme	copper	195:200	arg1	pollutant					223:231	a model pollutant	215:231	a model pollutant	215:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	1	23	theme	copper	195:200	arg1	}					210:210	copper {Cu (II)}	195:210	copper {Cu (II)}	195:210	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	2	24	theme	aqueous	377:383	arg1	solutions					385:393	aqueous solutions	377:393	aqueous solutions	377:393	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	8	25	theme	contact	1222:1228	arg1	conditions					1179:1188	different conditions	1169:1188	different conditions (initial concentration, pH, and contact time)	1169:1234	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	25	theme	contact	1222:1228	arg1	time					1230:1233	contact time	1222:1233	contact time	1222:1233	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	6	26	used	used	890:893	arg2	Fourier					839:845	Fourier	839:845	Fourier transform infrared spectroscopy (FTIR)	839:884	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	1	27	theme	{	202:202	arg1	pollutant					223:231	a model pollutant	215:231	a model pollutant	215:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	1	27	theme	{	202:202	arg1	}					210:210	copper {Cu (II)}	195:210	copper {Cu (II)}	195:210	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	0	28	theme	copper	11:16	arg1	Removal					0:6	Removal	0:6	Removal of copper using chitosan beads embedded with amidoxime	0:61	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	8	29	theme	initial	1191:1197	arg1	conditions					1179:1188	different conditions	1169:1188	different conditions (initial concentration, pH, and contact time)	1169:1234	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	29	theme	initial	1191:1197	arg1	concentration					1199:1211	initial concentration	1191:1211	initial concentration	1191:1211	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	1	30	theme	Cu	203:204	arg1	pollutant					223:231	a model pollutant	215:231	a model pollutant	215:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	1	30	theme	Cu	203:204	arg1	}					210:210	copper {Cu (II)}	195:210	copper {Cu (II)}	195:210	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	8	31	theme	composite	1135:1143	arg1	beads					1145:1149	CP/AOGO composite beads	1127:1149	CP/AOGO composite beads	1127:1149	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	4	32	theme	nitrile	518:524	arg1	GO-g-PAN					578:585	GO-g-PAN	578:585	GO-g-PAN	578:585	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	32	theme	nitrile	518:524	arg1	oxide					571:575	polyacrylonitrile grafted graphene oxide	536:575	polyacrylonitrile grafted graphene oxide (GO-g-PAN)	536:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	32	theme	nitrile	518:524	arg1	groups					526:531	The nitrile groups	514:531	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN)	514:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	9	33	from	solutions	1322:1330	arg1	potential					1262:1270	the potential	1258:1270	the potential of composite beads in copper removal from aqueous solutions	1258:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	9	33	from	solutions	1322:1330	arg1	removal					1301:1307	copper removal	1294:1307	copper removal from aqueous solutions	1294:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	5	34	theme	composite	814:822	arg1	beads					832:836	composite CP/AOGO beads	814:836	composite CP/AOGO beads	814:836	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	6	35	theme	beads	974:978	arg1	formation					951:959	the formation	947:959	the formation of composite beads	947:978	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	0	36	theme	chitosan	24:31	arg1	beads					33:37	chitosan beads	24:37	chitosan beads embedded with amidoxime	24:61	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	5	37	theme	polyvinyl	729:737	arg1	alcohol					739:745	polyvinyl alcohol	729:745	polyvinyl alcohol (PVA)	729:751	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	5	37	theme	polyvinyl	729:737	arg1	PVA					748:750	PVA	748:750	PVA	748:750	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	6	38	theme	composite	964:972	arg1	beads					974:978	composite beads	964:978	composite beads	964:978	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	5	39	theme	alcohol	739:745	arg1	blend					702:706	a blend	700:706	a blend of chitosan (CS) and polyvinyl alcohol (PVA)	700:751	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	5	40	theme	CP/AOGO	824:830	arg1	beads					832:836	composite CP/AOGO beads	814:836	composite CP/AOGO beads	814:836	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	8	41	theme	CP/AOGO	1127:1133	arg1	beads					1145:1149	CP/AOGO composite beads	1127:1149	CP/AOGO composite beads	1127:1149	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	7	42	dep	microscopic	999:1009	arg1	SEM					1012:1014	SEM	1012:1014	SEM	1012:1014	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	8	43	theme	different	1169:1177	arg1	pH					1214:1215	pH	1214:1215	pH	1214:1215	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	43	theme	different	1169:1177	arg1	conditions					1179:1188	different conditions	1169:1188	different conditions (initial concentration, pH, and contact time)	1169:1234	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	43	theme	different	1169:1177	arg1	concentration					1199:1211	initial concentration	1191:1211	initial concentration	1191:1211	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	8	43	theme	different	1169:1177	arg1	time					1230:1233	contact time	1222:1233	contact time	1222:1233	The adsorption of Cu (II) onto CP/AOGO composite beads was studied under different conditions (initial concentration, pH, and contact time).					
36167100	7	44	theme	microscopic	999:1009	arg1	analysis					1017:1024	Scanning electron microscopic (SEM) analysis	981:1024	Scanning electron microscopic (SEM) analysis	981:1024	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	0	45	theme	embedded	39:46	arg1	beads					33:37	chitosan beads	24:37	chitosan beads embedded with amidoxime	24:61	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	9	46	theme	beads	1285:1289	arg1	potential					1262:1270	the potential	1258:1270	the potential of composite beads in copper removal from aqueous solutions	1258:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	9	47	from	potential	1262:1270	arg1	removal					1301:1307	copper removal	1294:1307	copper removal from aqueous solutions	1294:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	9	47	from	potential	1262:1270	arg1	solutions					1322:1330	aqueous solutions	1314:1330	aqueous solutions	1314:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	7	48	theme	spherical	1075:1083	arg1	structure					1085:1093	a well-developed spherical structure	1058:1093	a well-developed spherical structure	1058:1093	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	2	49	theme	Novel	234:238	arg1	beads					250:254	Novel composite beads	234:254	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO)	234:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	1	50	theme	biopolymer-based	120:135	arg1	system					147:152	a biopolymer-based composite system	118:152	a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant	118:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	9	51	theme	copper	1294:1299	arg1	removal					1301:1307	copper removal	1294:1307	copper removal from aqueous solutions	1294:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
36167100	3	52	theme	graphene	488:495	arg1	substrate					503:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	For this purpose, acrylonitrile was first polymerized onto a gamma-irradiated and silanized graphene oxide substrate.					
36167100	3	53	theme	oxide	497:501	arg1	substrate					503:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	For this purpose, acrylonitrile was first polymerized onto a gamma-irradiated and silanized graphene oxide substrate.					
36167100	2	54	used	used	343:346	arg2	beads					250:254	Novel composite beads	234:254	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO)	234:310	Novel composite beads of chitosan and amidoxime grafted graphene oxide (AOGO) were successfully prepared and used for the Cu (II) removal from aqueous solutions.					
36167100	1	55	theme	composite	137:145	arg1	system					147:152	a biopolymer-based composite system	118:152	a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant	118:231	This study explores a biopolymer-based composite system for metal decontamination of water using copper {Cu (II)} as a model pollutant.					
36167100	4	56	theme	oxide	571:575	arg1	GO-g-PAN					578:585	GO-g-PAN	578:585	GO-g-PAN	578:585	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	56	theme	oxide	571:575	arg1	oxide					571:575	polyacrylonitrile grafted graphene oxide	536:575	polyacrylonitrile grafted graphene oxide (GO-g-PAN)	536:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	4	56	theme	oxide	571:575	arg1	groups					526:531	The nitrile groups	514:531	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN)	514:586	The nitrile groups of polyacrylonitrile grafted graphene oxide (GO-g-PAN) were then chemically modified into amidoxime groups to form AOGO nanohybrids.					
36167100	5	57	theme	chitosan	711:718	arg1	blend					702:706	a blend	700:706	a blend of chitosan (CS) and polyvinyl alcohol (PVA)	700:751	These nanohybrids were mixed with a blend of chitosan (CS) and polyvinyl alcohol (PVA) and crosslinked using tetraethylorthosilicate (TEOS) to form composite CP/AOGO beads.					
36167100	7	58	contain	had	1054:1056	arg1	beads					1048:1052	the beads	1044:1052	the beads	1044:1052	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	7	58	contain	had	1054:1056	arg2	structure					1085:1093	a well-developed spherical structure	1058:1093	a well-developed spherical structure	1058:1093	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	0	59	with	embedded	39:46	arg1	amidoxime					53:61	amidoxime	53:61	amidoxime	53:61	Removal of copper using chitosan beads embedded with amidoxime grafted graphene oxide nanohybids.					
36167100	3	60	theme	gamma-irradiated	457:472	arg1	substrate					503:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	a gamma-irradiated and silanized graphene oxide substrate	455:511	For this purpose, acrylonitrile was first polymerized onto a gamma-irradiated and silanized graphene oxide substrate.					
36167100	6	61	dep	Fourier	839:845	arg1	transform					847:855	transform	847:855	transform infrared spectroscopy (FTIR)	847:884	Fourier transform infrared spectroscopy (FTIR) was used to study the structural changes at each step during the formation of composite beads.					
36167100	7	62	theme	well-developed	1060:1073	arg1	structure					1085:1093	a well-developed spherical structure	1058:1093	a well-developed spherical structure	1058:1093	Scanning electron microscopic (SEM) analysis demonstrated that the beads had a well-developed spherical structure.					
36167100	9	63	theme	aqueous	1314:1320	arg1	solutions					1322:1330	aqueous solutions	1314:1330	aqueous solutions	1314:1330	The results revealed the potential of composite beads in copper removal from aqueous solutions.					
35944110	8	0	theme	immune	1633:1638	arg1	effect					1640:1645	the immune effect	1629:1645	the immune effect of oral vaccination	1629:1665	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	1	1	theme	aquaculture	274:284	arg1	industry					286:293	the largemouth bass aquaculture industry	254:293	the largemouth bass aquaculture industry in China	254:302	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	0	2	theme	immune	91:96	arg1	effect					98:103	the immune effect	87:103	the immune effect against Micropterus salmoides rhabdovirus	87:145	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	6	3	dep	indexes	1000:1006	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	3	dep	indexes	1000:1006	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	3	dep	indexes	1000:1006	arg1	phosphatase					1014:1024	acid phosphatase	1009:1024	acid phosphatase	1009:1024	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	3	dep	indexes	1000:1006	arg1	phosphatase					1036:1046	alkaline phosphatase	1027:1046	alkaline phosphatase	1027:1046	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	3	dep	indexes	1000:1006	arg1	dismutase					1060:1068	superoxide dismutase	1049:1068	superoxide dismutase	1049:1068	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	4	4	gly	glycoprotein	660:671	arg1	glycoprotein					660:671	MSRV glycoprotein	655:671	MSRV glycoprotein (G2 protein)	655:684	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	4	4	gly	glycoprotein	660:671	arg1	protein					677:683	G2 protein	674:683	G2 protein	674:683	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	8	5	theme	oral	1650:1653	arg1	vaccination					1655:1665	oral vaccination	1650:1665	oral vaccination	1650:1665	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	6	6	theme	physiological	986:998	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	6	theme	physiological	986:998	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	6	theme	physiological	986:998	arg1	phosphatase					1014:1024	acid phosphatase	1009:1024	acid phosphatase	1009:1024	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	6	theme	physiological	986:998	arg1	phosphatase					1036:1046	alkaline phosphatase	1027:1046	alkaline phosphatase	1027:1046	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	6	theme	physiological	986:998	arg1	dismutase					1060:1068	superoxide dismutase	1049:1068	superoxide dismutase	1049:1068	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	0	7	theme	Micropterus	113:123	arg1	salmoides					125:133	Micropterus salmoides	113:133	Micropterus salmoides rhabdovirus	113:145	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	7	8	theme	lethal	1313:1318	arg1	dose					1320:1323	a lethal dose	1311:1323	a lethal dose of MSRV	1311:1331	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	4	9	theme	largemouth	753:762	arg1	bass					764:767	largemouth bass	753:767	largemouth bass	753:767	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	4	10	theme	alginate-chitosan	578:594	arg1	microsphere					606:616	alginate-chitosan composite microsphere	578:616	alginate-chitosan composite microsphere	578:616	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	8	11	theme	immune	1685:1690	arg1	protection					1692:1701	better immune protection	1678:1701	better immune protection effect against MSRV infection	1678:1731	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	8	12	theme	vaccine	1589:1595	arg1	carrier					1597:1603	the vaccine carrier	1585:1603	the vaccine carrier	1585:1603	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	4	13	theme	immune	709:714	arg1	effect					716:721	the immune effect	705:721	the immune effect of the microsphere vaccine on largemouth bass	705:767	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	7	14	theme	40 μg	1450:1454	arg1	fish					1460:1463	40 μg per fish	1450:1463	40 μg per fish	1450:1463	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	14	theme	40 μg	1450:1454	arg1	group					1443:1447	SA-CS-G2 group	1434:1447	SA-CS-G2 group (40 μg per fish)	1434:1464	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	6	15	theme	antioxidant	1080:1090	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	15	theme	antioxidant	1080:1090	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	3	16	theme	vaccination	528:538	arg1	development					508:518	the development	504:518	the development of oral vaccination	504:538	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	8	17	theme	vaccination	1655:1665	arg1	effect					1640:1645	the immune effect	1629:1645	the immune effect of oral vaccination	1629:1665	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	4	18	theme	glycoprotein	660:671	arg1	segment					644:650	the second segment	633:650	the second segment of MSRV glycoprotein (G2 protein)	633:684	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	0	19	theme	salmoides	125:133	arg1	rhabdovirus					135:145	Micropterus salmoides rhabdovirus	113:145	Micropterus salmoides rhabdovirus	113:145	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	7	20	theme	SA-CS-G2	1434:1441	arg1	fish					1460:1463	40 μg per fish	1450:1463	40 μg per fish	1450:1463	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	20	theme	SA-CS-G2	1434:1441	arg1	group					1443:1447	SA-CS-G2 group	1434:1447	SA-CS-G2 group (40 μg per fish)	1434:1464	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	5	21	theme	Largemouth	770:779	arg1	bass					781:784	Largemouth bass	770:784	Largemouth bass	770:784	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	8	22	dep	protection	1692:1701	arg1	effect					1703:1708	effect	1703:1708	better immune protection effect against MSRV infection	1678:1731	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	5	23	theme	intragastric	806:817	arg1	immunization					819:830	intragastric immunization	806:830	intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2)	806:884	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	8	24	theme	better	1678:1683	arg1	protection					1692:1701	better immune protection	1678:1701	better immune protection effect against MSRV infection	1678:1731	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	3	25	theme	chitosan	455:462	arg1	SA-CS					478:482	SA-CS	478:482	SA-CS	478:482	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	25	theme	chitosan	455:462	arg1	kind					393:396	a kind	391:396	a kind of sustained and controlled release system	391:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	25	theme	chitosan	455:462	arg1	microspheres					464:475	alginate and chitosan microspheres	442:475	microspheres	464:475	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	0	26	theme	recombinant	4:14	arg1	vaccine					24:30	The recombinant subunit vaccine	0:30	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere	0:76	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	1	27	dep	salmoides	182:190	arg1	MSRV					205:208	MSRV	205:208	MSRV	205:208	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	1	27	dep	salmoides	182:190	arg1	rhabdovirus					192:202	rhabdovirus	192:202	Micropterus salmoides rhabdovirus (MSRV)	170:209	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	8	28	theme	alginate-chitosan	1551:1567	arg1	microspheres					1569:1580	alginate-chitosan microspheres	1551:1580	alginate-chitosan microspheres as the vaccine carrier	1551:1603	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	4	29	theme	G2	674:675	arg1	glycoprotein					660:671	MSRV glycoprotein	655:671	MSRV glycoprotein (G2 protein)	655:684	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	4	29	theme	G2	674:675	arg1	protein					677:683	G2 protein	674:683	G2 protein	674:683	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	3	30	theme	sustained	401:409	arg1	system					434:439	sustained and controlled release system	401:439	sustained and controlled release system	401:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	2	31	theme	potential	337:345	arg1	Vaccination					305:315	Vaccination	305:315	Vaccination	305:315	Vaccination was considered as a potential way to prevent and control this disease.					
35944110	2	31	theme	potential	337:345	arg1	way					347:349	a potential way	335:349	a potential way to prevent and control this disease	335:385	Vaccination was considered as a potential way to prevent and control this disease.					
35944110	3	32	theme	alginate	442:449	arg1	SA-CS					478:482	SA-CS	478:482	SA-CS	478:482	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	32	theme	alginate	442:449	arg1	kind					393:396	a kind	391:396	a kind of sustained and controlled release system	391:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	32	theme	alginate	442:449	arg1	microspheres					464:475	alginate and chitosan microspheres	442:475	microspheres	464:475	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	6	33	theme	antibody	954:961	arg1	levels					963:968	serum antibody levels	948:968	serum antibody levels	948:968	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	34	theme	G2	1237:1238	arg1	groups					1240:1245	G2 groups	1237:1245	G2 groups	1237:1245	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	4	35	theme	vaccine	742:748	arg1	effect					716:721	the immune effect	705:721	the immune effect of the microsphere vaccine on largemouth bass	705:767	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	6	36	theme	total	1074:1078	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	36	theme	total	1074:1078	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	4	37	theme	second	637:642	arg1	segment					644:650	the second segment	633:650	the second segment of MSRV glycoprotein (G2 protein)	633:684	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	0	38	theme	subunit	16:22	arg1	vaccine					24:30	The recombinant subunit vaccine	0:30	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere	0:76	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	6	39	theme	serum	948:952	arg1	levels					963:968	serum antibody levels	948:968	serum antibody levels	948:968	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	4	40	theme	microsphere	730:740	arg1	vaccine					742:748	the microsphere vaccine	726:748	the microsphere vaccine	726:748	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	1	41	theme	substantial	223:233	arg1	losses					244:249	substantial economic losses	223:249	substantial economic losses	223:249	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	3	42	theme	release	426:432	arg1	system					434:439	sustained and controlled release system	401:439	sustained and controlled release system	401:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	7	43	theme	G2	1510:1511	arg1	group					1513:1517	G2 group	1510:1517	G2 group (25.8%)	1510:1525	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	43	theme	G2	1510:1511	arg1	%					1524:1524	25.8%	1520:1524	25.8%	1520:1524	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	44	theme	relative	1381:1388	arg1	survival					1401:1408	the highest relative percentage survival	1369:1408	the highest relative percentage survival (54.8%)	1369:1416	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	44	theme	relative	1381:1388	arg1	%					1415:1415	54.8%	1411:1415	54.8%	1411:1415	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	45	theme	MSRV	1328:1331	arg1	dose					1320:1323	a lethal dose	1311:1323	a lethal dose of MSRV	1311:1331	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	1	46	theme	economic	235:242	arg1	losses					244:249	substantial economic losses	223:249	substantial economic losses	223:249	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	3	47	theme	system	434:439	arg1	kind					393:396	a kind	391:396	a kind of sustained and controlled release system	391:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	47	theme	system	434:439	arg1	microspheres					464:475	alginate and chitosan microspheres	442:475	microspheres	464:475	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	7	48	theme	per	1456:1458	arg1	fish					1460:1463	40 μg per fish	1450:1463	40 μg per fish	1450:1463	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	48	theme	per	1456:1458	arg1	group					1443:1447	SA-CS-G2 group	1434:1447	SA-CS-G2 group (40 μg per fish)	1434:1464	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	1	49	from	industry	286:293	arg1	China					298:302	China	298:302	China	298:302	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	6	50	theme	acid	1009:1012	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	50	theme	acid	1009:1012	arg1	phosphatase					1014:1024	acid phosphatase	1009:1024	acid phosphatase	1009:1024	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	7	51	theme	highest	1373:1379	arg1	survival					1401:1408	the highest relative percentage survival	1369:1408	the highest relative percentage survival (54.8%)	1369:1416	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	51	theme	highest	1373:1379	arg1	%					1415:1415	54.8%	1411:1415	54.8%	1411:1415	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	6	52	theme	alkaline	1027:1034	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	52	theme	alkaline	1027:1034	arg1	phosphatase					1036:1046	alkaline phosphatase	1027:1046	alkaline phosphatase	1027:1046	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	53	theme	immune	922:927	arg1	response					929:936	a stronger immune response	911:936	a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α)	911:1175	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	8	54	theme	MSRV	1718:1721	arg1	infection					1723:1731	MSRV infection	1718:1731	MSRV infection	1718:1731	This study showed that alginate-chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.					
35944110	6	55	theme	gene	1139:1142	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	phosphatase					1036:1046	alkaline phosphatase	1027:1046	alkaline phosphatase	1027:1046	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	levels					963:968	serum antibody levels	948:968	serum antibody levels	948:968	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	phosphatase					1014:1024	acid phosphatase	1009:1024	acid phosphatase	1009:1024	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	dismutase					1060:1068	superoxide dismutase	1049:1068	superoxide dismutase	1049:1068	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	55	theme	gene	1139:1142	arg1	expression					1110:1119	the expression	1106:1119	the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α)	1106:1175	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	0	56	theme	alginate-chitosan	48:64	arg1	microsphere					66:76	alginate-chitosan microsphere	48:76	alginate-chitosan microsphere	48:76	The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus.					
35944110	6	57	theme	stronger	913:920	arg1	response					929:936	a stronger immune response	911:936	a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α)	911:1175	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	3	58	used	used	496:499	arg2	SA-CS					478:482	SA-CS	478:482	SA-CS	478:482	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	58	used	used	496:499	arg2	microspheres					464:475	alginate and chitosan microspheres	442:475	microspheres	464:475	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	3	58	used	used	496:499	arg2	kind					393:396	a kind	391:396	a kind of sustained and controlled release system	391:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	6	59	theme	immune-related	1124:1137	arg1	IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α					1145:1174	IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α	1145:1174	IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α	1145:1174	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	59	theme	immune-related	1124:1137	arg1	gene					1139:1142	immune-related gene	1124:1142	immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α)	1124:1175	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	4	60	from	effect	716:721	arg1	bass					764:767	largemouth bass	753:767	largemouth bass	753:767	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	6	61	theme	SA-CS-G2	1207:1214	arg1	groups					1216:1221	SA-CS-G2 groups	1207:1221	SA-CS-G2 groups compared with G2 groups when fish were vaccinated	1207:1271	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	7	62	theme	percentage	1390:1399	arg1	survival					1401:1408	the highest relative percentage survival	1369:1408	the highest relative percentage survival (54.8%)	1369:1416	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	62	theme	percentage	1390:1399	arg1	%					1415:1415	54.8%	1411:1415	54.8%	1411:1415	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	2	63	dep	way	347:349	arg1	control					366:372	control	366:372	control this disease	366:385	Vaccination was considered as a potential way to prevent and control this disease.					
35944110	2	63	dep	way	347:349	arg1	prevent					354:360	prevent	354:360	prevent	354:360	Vaccination was considered as a potential way to prevent and control this disease.					
35944110	4	64	theme	microsphere	606:616	arg1	king					570:573	king	570:573	king	570:573	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	6	65	theme	superoxide	1049:1058	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	65	theme	superoxide	1049:1058	arg1	dismutase					1060:1068	superoxide dismutase	1049:1068	superoxide dismutase	1049:1068	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	3	66	theme	oral	523:526	arg1	vaccination					528:538	oral vaccination	523:538	oral vaccination	523:538	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	4	67	theme	composite	596:604	arg1	microsphere					606:616	alginate-chitosan composite microsphere	578:616	alginate-chitosan composite microsphere	578:616	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	5	68	theme	different	835:843	arg1	SA-CS					862:866	SA-CS	862:866	SA-CS	862:866	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	68	theme	different	835:843	arg1	PBS					857:859	PBS	857:859	PBS	857:859	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	68	theme	different	835:843	arg1	SA-CS-G2					876:883	SA-CS-G2	876:883	SA-CS-G2	876:883	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	68	theme	different	835:843	arg1	treatments					845:854	different treatments	835:854	different treatments (PBS, SA-CS, G2 and SA-CS-G2)	835:884	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	68	theme	different	835:843	arg1	G2					869:870	G2	869:870	G2	869:870	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	3	69	theme	controlled	415:424	arg1	system					434:439	sustained and controlled release system	401:439	sustained and controlled release system	401:439	As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA-CS) are widely used in the development of oral vaccination for fish.					
35944110	4	70	theme	MSRV	655:658	arg1	glycoprotein					660:671	MSRV glycoprotein	655:671	MSRV glycoprotein (G2 protein)	655:684	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	4	70	theme	MSRV	655:658	arg1	protein					677:683	G2 protein	674:683	G2 protein	674:683	Here, we prepared a king of alginate-chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass.					
35944110	1	71	theme	largemouth	258:267	arg1	industry					286:293	the largemouth bass aquaculture industry	254:293	the largemouth bass aquaculture industry in China	254:302	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	6	72	theme	immune-related	971:984	arg1	capacity					1092:1099	total antioxidant capacity	1074:1099	total antioxidant capacity	1074:1099	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	72	theme	immune-related	971:984	arg1	indexes					1000:1006	immune-related physiological indexes	971:1006	immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity)	971:1100	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	72	theme	immune-related	971:984	arg1	phosphatase					1014:1024	acid phosphatase	1009:1024	acid phosphatase	1009:1024	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	72	theme	immune-related	971:984	arg1	phosphatase					1036:1046	alkaline phosphatase	1027:1046	alkaline phosphatase	1027:1046	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	6	72	theme	immune-related	971:984	arg1	dismutase					1060:1068	superoxide dismutase	1049:1068	superoxide dismutase	1049:1068	The results showed that a stronger immune response including serum antibody levels, immune-related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune-related gene (IgM、IL-8、IL-1β、CD4、TGF-β、TNF-α) can be induced obviously with SA-CS-G2 groups compared with G2 groups when fish were vaccinated.					
35944110	7	73	located	observed	1422:1429	arg2	survival					1401:1408	the highest relative percentage survival	1369:1408	the highest relative percentage survival (54.8%)	1369:1416	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	73	located	observed	1422:1429	arg2	%					1415:1415	54.8%	1411:1415	54.8%	1411:1415	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	73	located	observed	1422:1429	arg1	group					1443:1447	SA-CS-G2 group	1434:1447	SA-CS-G2 group (40 μg per fish)	1434:1464	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	7	73	located	observed	1422:1429	arg1	fish					1460:1463	40 μg per fish	1450:1463	40 μg per fish	1450:1463	Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA-CS-G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%).					
35944110	5	74	dep	treatments	845:854	arg1	treatments					845:854	different treatments	835:854	different treatments (PBS, SA-CS, G2 and SA-CS-G2)	835:884	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	74	dep	treatments	845:854	arg1	SA-CS					862:866	SA-CS	862:866	SA-CS	862:866	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	74	dep	treatments	845:854	arg1	PBS					857:859	PBS	857:859	PBS	857:859	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	74	dep	treatments	845:854	arg1	SA-CS-G2					876:883	SA-CS-G2	876:883	SA-CS-G2	876:883	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	5	74	dep	treatments	845:854	arg1	G2					869:870	G2	869:870	G2	869:870	Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA-CS, G2 and SA-CS-G2).					
35944110	1	75	theme	Micropterus	170:180	arg1	salmoides					182:190	Micropterus salmoides rhabdovirus (MSRV)	170:209	Micropterus salmoides rhabdovirus (MSRV)	170:209	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
35944110	1	76	theme	bass	269:272	arg1	industry					286:293	the largemouth bass aquaculture industry	254:293	the largemouth bass aquaculture industry in China	254:302	The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China.					
36372485	4	0	theme	microfibrous	565:576	arg1	materials					588:596	conventional microfibrous cellulose materials	552:596	conventional microfibrous cellulose materials	552:596	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	7	1	theme	silver	1099:1104	arg1	composites					1129:1138	silver nanoparticle-cellulose composites	1099:1138	silver nanoparticle-cellulose composites with bactericidal activities	1099:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	8	2	theme	functional	1226:1235	arg1	materials					1237:1245	cellulose-based functional materials	1210:1245	cellulose-based functional materials with nanostructures designed via molecular self-assembly	1210:1302	Our findings promote the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly.					
36372485	1	3	theme	sustainable	175:185	arg1	nanofibers					142:151	cellulose nanofibers	132:151	cellulose nanofibers	132:151	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	1	3	theme	sustainable	175:185	arg1	Nanocelluloses					108:121	Nanocelluloses	108:121	Nanocelluloses	108:121	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	1	3	theme	sustainable	175:185	arg1	nanomaterials					187:199	sustainable nanomaterials	175:199	sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner	175:276	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	1	3	theme	sustainable	175:185	arg1	nanocrystals					157:168	nanocrystals	157:168	nanocrystals	157:168	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	7	4	theme	nanoparticle-cellulose	1106:1127	arg1	composites					1129:1138	silver nanoparticle-cellulose composites	1099:1138	silver nanoparticle-cellulose composites with bactericidal activities	1099:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	4	5	theme	materials	588:596	arg1	nanostructuring					533:547	bottom-up nanostructuring	523:547	bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy	523:635	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	5	6	theme	partial	737:743	arg1	dissolution					745:755	partial dissolution	737:755	partial dissolution	737:755	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	3	7	theme	conventional	408:419	arg1	materials					432:440	conventional cellulosic materials	408:440	conventional cellulosic materials	408:440	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	3	8	theme	creating	379:386	arg1	nanostructures					388:401	creating nanostructures	379:401	creating nanostructures from conventional cellulosic materials including paper and cloth	379:466	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	3	8	theme	creating	379:386	arg1	paper					452:456	paper	452:456	paper	452:456	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	3	8	theme	creating	379:386	arg1	cloth					462:466	cloth	462:466	cloth	462:466	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	4	9	theme	bottom-up	523:531	arg1	nanostructuring					533:547	bottom-up nanostructuring	523:547	bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy	523:635	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	4	10	theme	conventional	552:563	arg1	materials					588:596	conventional microfibrous cellulose materials	552:596	conventional microfibrous cellulose materials	552:596	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	5	11	theme	aqueous	705:711	arg1	acid					724:727	aqueous phosphoric acid	705:727	aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose	705:783	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	12	theme	cellulose	653:661	arg1	paper					673:677	paper	673:677	paper	673:677	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	12	theme	cellulose	653:661	arg1	material					663:670	a precursor cellulose material	641:670	a precursor cellulose material	641:670	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	13	dep	dissolution	745:755	arg1	the					733:735	the	733:735	the	733:735	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	14	theme	phosphoric	713:722	arg1	acid					724:727	aqueous phosphoric acid	705:727	aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose	705:783	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	3	15	from	materials	432:440	arg1	nanostructures					388:401	creating nanostructures	379:401	creating nanostructures from conventional cellulosic materials including paper and cloth	379:466	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	3	15	from	materials	432:440	arg1	paper					452:456	paper	452:456	paper	452:456	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	3	15	from	materials	432:440	arg1	cloth					462:466	cloth	462:466	cloth	462:466	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	0	16	theme	Nanospiked	0:9	arg1	paper					11:15	Nanospiked paper	0:15	Nanospiked paper	0:15	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	8	17	theme	cellulose-based	1210:1224	arg1	materials					1237:1245	cellulose-based functional materials	1210:1245	cellulose-based functional materials with nanostructures designed via molecular self-assembly	1210:1302	Our findings promote the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly.					
36372485	3	18	theme	cellulosic	421:430	arg1	materials					432:440	conventional cellulosic materials	408:440	conventional cellulosic materials	408:440	However, creating nanostructures from conventional cellulosic materials including paper and cloth remains challenging.					
36372485	2	19	theme	new	337:339	arg1	applications					341:352	new applications	337:352	new applications of biopolymers	337:367	These nanomaterials and their assemblies are facilitating new applications of biopolymers.					
36372485	6	20	from	assemblies	976:985	arg1	surfaces					1005:1012	the microfiber surfaces	990:1012	the microfiber surfaces	990:1012	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	8	21	theme	materials	1237:1245	arg1	development					1195:1205	the development	1191:1205	the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly	1191:1302	Our findings promote the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly.					
36372485	6	22	from	cello-oligosaccharides	845:866	arg1	state					883:887	a dissolved state	871:887	a dissolved state	871:887	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	8	23	with	materials	1237:1245	arg1	nanostructures					1252:1265	nanostructures	1252:1265	nanostructures designed via molecular self-assembly	1252:1302	Our findings promote the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly.					
36372485	1	24	theme	natural	235:241	arg1	materials					247:255	natural raw materials	235:255	natural raw materials	235:255	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	0	25	theme	cellulose	31:39	arg1	materials					41:49	Microfibrous cellulose materials	18:49	Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly	18:105	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	4	26	theme	molecular	604:612	arg1	strategy					628:635	a molecular self-assembly strategy	602:635	a molecular self-assembly strategy	602:635	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	5	27	theme	microfibrous	807:818	arg1	structure					820:828	its microfibrous structure	803:828	its microfibrous structure	803:828	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	6	28	theme	nanospike-like	961:974	arg1	assemblies					976:985	nanospike-like assemblies	961:985	nanospike-like assemblies on the microfiber surfaces	961:1012	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	0	29	theme	Microfibrous	18:29	arg1	materials					41:49	Microfibrous cellulose materials	18:49	Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly	18:105	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	6	30	theme	dissolved	873:881	arg1	state					883:887	a dissolved state	871:887	a dissolved state	871:887	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	1	31	theme	raw	243:245	arg1	materials					247:255	natural raw materials	235:255	natural raw materials	235:255	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	8	32	theme	molecular	1280:1288	arg1	self-assembly					1290:1302	molecular self-assembly	1280:1302	molecular self-assembly	1280:1302	Our findings promote the development of cellulose-based functional materials with nanostructures designed via molecular self-assembly.					
36372485	0	33	dep	materials	41:49	arg1	paper					11:15	Nanospiked paper	0:15	Nanospiked paper	0:15	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	6	34	theme	microfiber	994:1003	arg1	surfaces					1005:1012	the microfiber surfaces	990:1012	the microfiber surfaces	990:1012	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	0	35	theme	nanostructured	51:64	arg1	materials					41:49	Microfibrous cellulose materials	18:49	Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly	18:105	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	1	36	theme	cellulose	132:140	arg1	nanofibers					142:151	cellulose nanofibers	132:151	cellulose nanofibers	132:151	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36372485	7	37	theme	nanospiked	1029:1038	arg1	precursor					1072:1080	a precursor	1070:1080	a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities	1070:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	7	37	theme	nanospiked	1029:1038	arg1	papers					1040:1045	The resultant nanospiked papers	1015:1045	The resultant nanospiked papers	1015:1045	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	4	38	theme	self-assembly	614:626	arg1	strategy					628:635	a molecular self-assembly strategy	602:635	a molecular self-assembly strategy	602:635	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	5	39	theme	precursor	643:651	arg1	paper					673:677	paper	673:677	paper	673:677	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	39	theme	precursor	643:651	arg1	material					663:670	a precursor cellulose material	641:670	a precursor cellulose material	641:670	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	40	theme	cellulose	775:783	arg1	hydrolysis					761:770	hydrolysis	761:770	hydrolysis	761:770	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	5	40	theme	cellulose	775:783	arg1	dissolution					745:755	partial dissolution	737:755	partial dissolution	737:755	As a precursor cellulose material, paper was allowed to swell with aqueous phosphoric acid for the partial dissolution and hydrolysis of cellulose while maintaining its microfibrous structure.					
36372485	6	41	theme	generated	835:843	arg1	cello-oligosaccharides					845:866	The generated cello-oligosaccharides	831:866	The generated cello-oligosaccharides in a dissolved state	831:887	The generated cello-oligosaccharides in a dissolved state started to self-assemble upon adding water as a coagulant, resulting in nanospike-like assemblies on the microfiber surfaces.					
36372485	2	42	theme	biopolymers	357:367	arg1	applications					341:352	new applications	337:352	new applications of biopolymers	337:367	These nanomaterials and their assemblies are facilitating new applications of biopolymers.					
36372485	7	43	theme	bactericidal	1145:1156	arg1	activities					1158:1167	bactericidal activities	1145:1167	bactericidal activities	1145:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	7	44	theme	resultant	1019:1027	arg1	precursor					1072:1080	a precursor	1070:1080	a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities	1070:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	7	44	theme	resultant	1019:1027	arg1	papers					1040:1045	The resultant nanospiked papers	1015:1045	The resultant nanospiked papers	1015:1045	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	0	45	theme	partial	70:76	arg1	hydrolysis					78:87	partial hydrolysis	70:87	partial hydrolysis	70:87	Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly.					
36372485	4	46	theme	cellulose	578:586	arg1	materials					588:596	conventional microfibrous cellulose materials	552:596	conventional microfibrous cellulose materials	552:596	Herein, we report an approach for bottom-up nanostructuring of conventional microfibrous cellulose materials via a molecular self-assembly strategy.					
36372485	7	47	with	composites	1129:1138	arg1	activities					1158:1167	bactericidal activities	1145:1167	bactericidal activities	1145:1167	The resultant nanospiked papers were found to serve as a precursor for synthesizing silver nanoparticle-cellulose composites with bactericidal activities.					
36372485	1	48	theme	top-down	262:269	arg1	manner					271:276	a top-down manner	260:276	a top-down manner	260:276	Nanocelluloses, such as cellulose nanofibers and nanocrystals, are sustainable nanomaterials that are generally extracted from natural raw materials in a top-down manner.					
36925247	6	0	theme	DOX	1346:1348	arg1	chemotherapy					1330:1341	chemotherapy	1330:1341	chemotherapy of DOX	1330:1348	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	6	0	theme	DOX	1346:1348	arg1	MPDA					1324:1327	MPDA	1324:1327	MPDA	1324:1327	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	5	1	theme	@	1090:1090	arg1	complex					1078:1084	the curcumin-cyclodextrin host-guest inclusion complex	1031:1084	the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1031:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	1	theme	@	1090:1090	arg1	NH2-CD					1091:1096	CUR@NH2-CD	1087:1096	CUR@NH2-CD	1087:1096	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	6	2	theme	chemotherapy	1330:1341	arg1	efficacy					1312:1319	the admired photothermal efficacy	1287:1319	the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1287:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	7	3	contain	has	1428:1430	arg1	hydrogel					1419:1426	the composite hydrogel	1405:1426	the composite hydrogel	1405:1426	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	7	3	contain	has	1428:1430	arg2	prospect					1440:1447	a broad prospect	1432:1447	a broad prospect	1432:1447	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	0	4	theme	photothermal-chemo	99:116	arg1	therapy					118:124	simultaneous photothermal-chemo therapy	86:124	simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	86:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	6	5	theme	effect	1277:1282	arg1	virtue					1249:1254	virtue	1249:1254	virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1249:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	0	6	with	therapy	118:124	arg1	capacity					159:166	anti-inflammatory capacity	141:166	anti-inflammatory capacity	141:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	2	7	theme	blurred	365:371	arg1	boundary					373:380	the blurred boundary	361:380	the blurred boundary between normal and necrotic tissues	361:416	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	1	8	theme	local	288:292	arg1	temperature					299:309	local high temperature	288:309	local high temperature	288:309	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	0	9	theme	cancer	129:134	arg1	therapy					118:124	simultaneous photothermal-chemo therapy	86:124	simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	86:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	7	10	theme	broad	1434:1438	arg1	prospect					1440:1447	a broad prospect	1432:1447	a broad prospect	1432:1447	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	1	11	theme	high	294:297	arg1	temperature					299:309	local high temperature	288:309	local high temperature	288:309	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	4	12	theme	DOX	913:915	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	12	theme	DOX	913:915	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	12	theme	DOX	913:915	arg1	reservoir					900:908	a reservoir	898:908	a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release	898:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	5	13	theme	complex	1078:1084	arg1	addition					1019:1026	the addition	1015:1026	the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1015:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	14	from	hydrogel	1116:1123	arg1	addition					1019:1026	the addition	1015:1026	the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1015:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	0	15	theme	anti-inflammatory	141:157	arg1	capacity					159:166	anti-inflammatory capacity	141:166	anti-inflammatory capacity	141:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	4	16	theme	MPDA	815:818	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	16	theme	MPDA	815:818	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	16	theme	MPDA	815:818	arg1	reservoir					900:908	a reservoir	898:908	a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release	898:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	2	17	theme	serious	511:517	arg1	inflammation					519:530	serious inflammation	511:530	serious inflammation in local tissues	511:547	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	5	18	theme	CUR	1087:1089	arg1	complex					1078:1084	the curcumin-cyclodextrin host-guest inclusion complex	1031:1084	the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1031:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	18	theme	CUR	1087:1089	arg1	NH2-CD					1091:1096	CUR@NH2-CD	1087:1096	CUR@NH2-CD	1087:1096	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	4	19	theme	drug	992:995	arg1	release					997:1003	pulsed drug release	985:1003	pulsed drug release	985:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	7	20	theme	composite	1409:1417	arg1	hydrogel					1419:1426	the composite hydrogel	1405:1426	the composite hydrogel	1405:1426	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	6	21	theme	MPDA	1324:1327	arg1	efficacy					1312:1319	the admired photothermal efficacy	1287:1319	the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1287:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	2	22	theme	excessive	485:493	arg1	heat					495:498	excessive heat	485:498	excessive heat	485:498	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	6	23	theme	tumor	1221:1225	arg1	inhibition					1227:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	5	24	from	addition	1019:1026	arg1	hydrogel					1116:1123	the composite hydrogel	1102:1123	the composite hydrogel	1102:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	3	25	theme	composite	572:580	arg1	hydrogel					582:589	an injectable composite hydrogel	558:589	an injectable composite hydrogel	558:589	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	4	26	dep	good	940:943	arg1	photothermal					945:956	photothermal	945:956	photothermal	945:956	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	2	27	theme	necrotic	401:408	arg1	tissues					410:416	normal and necrotic tissues	390:416	normal and necrotic tissues	390:416	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	0	28	theme	Injectable	0:9	arg1	nano-composite					11:24	Injectable nano-composite	0:24	Injectable nano-composite	0:24	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	3	29	theme	delivery	721:728	arg1	substrate					730:738	the delivery substrate	717:738	the delivery substrate for functional substances	717:764	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	29	theme	delivery	721:728	arg1	bonds					689:693	the imine bonds	679:693	the imine bonds	679:693	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	6	30	theme	Hepa1-6	1213:1219	arg1	inhibition					1227:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	2	31	theme	irregular	332:340	arg1	edges					342:346	the irregular edges	328:346	the irregular edges of tumor	328:355	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	0	32	theme	acid-chitosan	56:68	arg1	derivatives					70:80	hyaluronic acid-chitosan derivatives	45:80	hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	45:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	5	33	theme	curcumin-cyclodextrin	1035:1055	arg1	complex					1078:1084	the curcumin-cyclodextrin host-guest inclusion complex	1031:1084	the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1031:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	33	theme	curcumin-cyclodextrin	1035:1055	arg1	NH2-CD					1091:1096	CUR@NH2-CD	1087:1096	CUR@NH2-CD	1087:1096	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	34	from	complex	1078:1084	arg1	hydrogel					1116:1123	the composite hydrogel	1102:1123	the composite hydrogel	1102:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	6	35	theme	efficacy	1312:1319	arg1	effect					1277:1282	the comprehensive effect	1259:1282	the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1259:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	1	36	theme	widespread	223:232	arg1	attention					234:242	widespread attention	223:242	widespread attention	223:242	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	4	37	theme	gel	774:776	arg1	medium					778:783	the gel medium	770:783	the gel medium	770:783	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	6	38	theme	photothermal	1299:1310	arg1	efficacy					1312:1319	the admired photothermal efficacy	1287:1319	the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1287:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	3	39	theme	injectable	561:570	arg1	hydrogel					582:589	an injectable composite hydrogel	558:589	an injectable composite hydrogel	558:589	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	2	40	theme	treatment	433:441	arg1	cannot					443:448	the desirable treatment cannot	419:448	the desirable treatment cannot	419:448	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	0	41	theme	hyaluronic	45:54	arg1	derivatives					70:80	hyaluronic acid-chitosan derivatives	45:80	hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	45:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	6	42	theme	anti-inflammatory	1354:1370	arg1	efficacy					1312:1319	the admired photothermal efficacy	1287:1319	the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1287:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	6	43	theme	admired	1291:1297	arg1	efficacy					1312:1319	the admired photothermal efficacy	1287:1319	the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1287:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	3	44	theme	hydroxypropyl	645:657	arg1	HPCS					669:672	HPCS	669:672	HPCS	669:672	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	44	theme	hydroxypropyl	645:657	arg1	chitosan					659:666	hydroxypropyl chitosan	645:666	hydroxypropyl chitosan (HPCS)	645:673	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	2	45	theme	desirable	423:431	arg1	cannot					443:448	the desirable treatment cannot	419:448	the desirable treatment cannot	419:448	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	4	46	theme	conversion	958:967	arg1	performance					969:979	the good photothermal conversion performance	936:979	the good photothermal conversion performance	936:979	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	47	theme	good	940:943	arg1	performance					969:979	the good photothermal conversion performance	936:979	the good photothermal conversion performance	936:979	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	5	48	theme	host-guest	1057:1066	arg1	complex					1078:1084	the curcumin-cyclodextrin host-guest inclusion complex	1031:1084	the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1031:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	48	theme	host-guest	1057:1066	arg1	NH2-CD					1091:1096	CUR@NH2-CD	1087:1096	CUR@NH2-CD	1087:1096	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	6	49	theme	favorable	1199:1207	arg1	inhibition					1227:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	favorable the Hepa1-6 tumor inhibition	1199:1236	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	4	50	theme	pulsed	985:990	arg1	release					997:1003	pulsed drug release	985:1003	pulsed drug release	985:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	2	51	theme	local	535:539	arg1	tissues					541:547	local tissues	535:547	local tissues	535:547	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	4	52	theme	efficiency	864:873	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	52	theme	efficiency	864:873	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	5	53	theme	inclusion	1068:1076	arg1	complex					1078:1084	the curcumin-cyclodextrin host-guest inclusion complex	1031:1084	the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel	1031:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	5	53	theme	inclusion	1068:1076	arg1	NH2-CD					1091:1096	CUR@NH2-CD	1087:1096	CUR@NH2-CD	1087:1096	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	4	54	theme	polydopamine	801:812	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	54	theme	polydopamine	801:812	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	54	theme	polydopamine	801:812	arg1	reservoir					900:908	a reservoir	898:908	a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release	898:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	2	55	theme	single	469:474	arg1	PTT					476:478	the single PTT	465:478	the single PTT	465:478	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	4	56	theme	high	859:862	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	56	theme	high	859:862	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	2	57	from	inflammation	519:530	arg1	tissues					541:547	local tissues	535:547	local tissues	535:547	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	4	58	theme	mesoporous	790:799	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	58	theme	mesoporous	790:799	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	58	theme	mesoporous	790:799	arg1	reservoir					900:908	a reservoir	898:908	a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release	898:1003	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	5	59	theme	composite	1106:1114	arg1	hydrogel					1116:1123	the composite hydrogel	1102:1123	the composite hydrogel	1102:1123	Besides, the addition of the curcumin-cyclodextrin host-guest inclusion complex (CUR@NH2-CD) in the composite hydrogel could reduce the inflammation caused by PTT.					
36925247	7	60	theme	therapy	1479:1485	arg1	field					1456:1460	the field	1452:1460	the field of comprehensive therapy for tumor	1452:1495	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	3	61	theme	functional	744:753	arg1	substances					755:764	functional substances	744:764	functional substances	744:764	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	6	62	theme	comprehensive	1263:1275	arg1	effect					1277:1282	the comprehensive effect	1259:1282	the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR	1259:1377	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	7	63	theme	comprehensive	1465:1477	arg1	therapy					1479:1485	comprehensive therapy	1465:1485	comprehensive therapy for tumor	1465:1495	It can be predicted that the composite hydrogel has a broad prospect in the field of comprehensive therapy for tumor.					
36925247	6	64	theme	composite	1174:1182	arg1	hydrogel					1184:1191	The composite hydrogel	1170:1191	The composite hydrogel	1170:1191	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	1	65	theme	Nowadays	169:176	arg1	PTT					205:207	PTT	205:207	PTT	205:207	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	1	65	theme	Nowadays	169:176	arg1	therapy					196:202	Nowadays, the photothermal therapy	169:202	therapy	196:202	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	4	66	theme	photothermal	875:886	arg1	nanoparticles					821:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	the mesoporous polydopamine (MPDA) nanoparticles	786:833	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	4	66	theme	photothermal	875:886	arg1	agent					888:892	the high efficiency photothermal agent	855:892	the high efficiency photothermal agent	855:892	In the gel medium, the mesoporous polydopamine (MPDA) nanoparticles are incorporated as the high efficiency photothermal agent and a reservoir of DOX, which can achieve the good photothermal conversion performance and pulsed drug release.					
36925247	0	67	dep	hydrogels	26:34	arg1	based					36:40	based	36:40	hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	26:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	2	68	theme	tumor	351:355	arg1	boundary					373:380	the blurred boundary	361:380	the blurred boundary between normal and necrotic tissues	361:416	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	2	68	theme	tumor	351:355	arg1	edges					342:346	the irregular edges	328:346	the irregular edges of tumor	328:355	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	0	69	theme	simultaneous	86:97	arg1	therapy					118:124	simultaneous photothermal-chemo therapy	86:124	simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity	86:166	Injectable nano-composite hydrogels based on hyaluronic acid-chitosan derivatives for simultaneous photothermal-chemo therapy of cancer with anti-inflammatory capacity.					
36925247	3	70	theme	oxidized	610:617	arg1	OHA					636:638	OHA	636:638	OHA	636:638	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	70	theme	oxidized	610:617	arg1	acid					630:633	the oxidized hyaluronic acid	606:633	the oxidized hyaluronic acid (OHA)	606:639	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	1	71	with	tumors	276:281	arg1	temperature					299:309	local high temperature	288:309	local high temperature	288:309	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	2	72	theme	normal	390:395	arg1	tissues					410:416	normal and necrotic tissues	390:416	normal and necrotic tissues	390:416	However, due to the irregular edges of tumor and the blurred boundary between normal and necrotic tissues, the desirable treatment cannot be achieved by the single PTT, and excessive heat will cause serious inflammation in local tissues.					
36925247	1	73	theme	killing	268:274	arg1	tumors					276:281	rapidly killing tumors	260:281	rapidly killing tumors with local high temperature	260:309	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	6	74	theme	CUR	1375:1377	arg1	anti-inflammatory					1354:1370	anti-inflammatory	1354:1370	anti-inflammatory	1354:1370	The composite hydrogel shows favorable the Hepa1-6 tumor inhibition in vivo by virtue of the comprehensive effect of the admired photothermal efficacy of MPDA, chemotherapy of DOX and anti-inflammatory of CUR.					
36925247	3	75	theme	imine	683:687	arg1	bonds					689:693	the imine bonds	679:693	the imine bonds	679:693	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	75	theme	imine	683:687	arg1	substrate					730:738	the delivery substrate	717:738	the delivery substrate for functional substances	717:764	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	76	theme	hyaluronic	619:628	arg1	OHA					636:638	OHA	636:638	OHA	636:638	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	3	76	theme	hyaluronic	619:628	arg1	acid					630:633	the oxidized hyaluronic acid	606:633	the oxidized hyaluronic acid (OHA)	606:639	Herein, an injectable composite hydrogel is prepared by the oxidized hyaluronic acid (OHA) and hydroxypropyl chitosan (HPCS) via the imine bonds, which is employed as the delivery substrate for functional substances.					
36925247	1	77	theme	photothermal	183:194	arg1	PTT					205:207	PTT	205:207	PTT	205:207	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
36925247	1	77	theme	photothermal	183:194	arg1	therapy					196:202	Nowadays, the photothermal therapy	169:202	therapy	196:202	Nowadays, the photothermal therapy (PTT) has received widespread attention and research by rapidly killing tumors with local high temperature.					
35272498	12	0	theme	Impact	1820:1825	arg1	control					1845:1851	Impact statement Precise control	1820:1851	Impact statement Precise control over the release of therapeutic agents	1820:1890	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	14	1	theme	therapeutic	2234:2244	arg1	agents					2246:2251	other therapeutic agents	2228:2251	other therapeutic agents	2228:2251	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	6	2	theme	titanium	884:891	arg1	disks					893:897	commercially pure titanium disks	866:897	commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD)	866:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	7	3	theme	Cu	1082:1083	arg1	kinetics					1093:1100	the Cu release kinetics	1078:1100	the Cu release kinetics	1078:1100	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	8	4	theme	gingival	1151:1158	arg1	fibroblasts					1160:1170	Human gingival fibroblasts	1145:1170	Human gingival fibroblasts	1145:1170	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	11	5	theme	EPD	1666:1668	arg1	method					1670:1675	the EPD method	1662:1675	the EPD method	1662:1675	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	11	5	theme	EPD	1666:1668	arg1	suitable					1680:1687	suitable	1680:1687	suitable	1680:1687	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	5	6	theme	bioactive	631:639	arg1	glass					641:645	mesoporous bioactive glass	620:645	mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu	620:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	5	6	theme	bioactive	631:639	arg1	MBG					648:650	MBG	648:650	MBG	648:650	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	9	7	contain	containing	1419:1428	arg2	Cu-MBG					1447:1452	Cu-MBG	1447:1452	Cu-MBG	1447:1452	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	7	contain	containing	1419:1428	arg2	Cu-free					1458:1464	Cu-free	1458:1464	Cu-free	1458:1464	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	7	contain	containing	1419:1428	arg1	coatings					1410:1417	coatings	1410:1417	coatings containing equal amounts of Cu-MBG and Cu-free MBG	1410:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	7	contain	containing	1419:1428	arg2	amounts					1436:1442	equal amounts	1430:1442	equal amounts of Cu-MBG and Cu-free MBG	1430:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	2	8	theme	soft	284:287	arg1	integration					296:306	soft tissue integration	284:306	soft tissue integration	284:306	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	6	9	theme	coatings	854:861	arg1	series					834:839	a series	832:839	a series of composite coatings	832:861	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	8	10	theme	highest	1240:1246	arg1	Cu					1258:1259	Cu	1258:1259	Cu	1258:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	8	10	theme	highest	1240:1246	arg1	amount					1248:1253	the highest amount	1236:1253	the highest amount of Cu	1236:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	6	11	theme	MBG	759:761	arg1	nanoparticles					763:775	Cu-free MBG nanoparticles	751:775	Cu-free MBG nanoparticles	751:775	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	9	12	theme	Cu-MBG	1447:1452	arg1	Cu-free					1458:1464	Cu-free	1458:1464	Cu-free	1458:1464	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	12	theme	Cu-MBG	1447:1452	arg1	Cu-MBG					1447:1452	Cu-MBG	1447:1452	Cu-MBG	1447:1452	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	12	theme	Cu-MBG	1447:1452	arg1	amounts					1436:1442	equal amounts	1430:1442	equal amounts of Cu-MBG and Cu-free MBG	1430:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	6	13	theme	implants	953:960	arg1	components					934:943	transmucosal components	921:943	transmucosal components of bone implants through electrophoretic deposition (EPD)	921:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	7	14	theme	composite	1044:1052	arg1	coatings					1054:1061	the composite coatings	1040:1061	the composite coatings	1040:1061	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	9	15	theme	Cu-free	1458:1464	arg1	Cu-free					1458:1464	Cu-free	1458:1464	Cu-free	1458:1464	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	15	theme	Cu-free	1458:1464	arg1	Cu-MBG					1447:1452	Cu-MBG	1447:1452	Cu-MBG	1447:1452	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	15	theme	Cu-free	1458:1464	arg1	amounts					1436:1442	equal amounts	1430:1442	equal amounts of Cu-MBG and Cu-free MBG	1430:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	10	16	dep	fivefold	1582:1589	arg1	up					1576:1577	up	1576:1577	up	1576:1577	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
35272498	6	17	theme	transmucosal	921:932	arg1	components					934:943	transmucosal components	921:943	transmucosal components of bone implants through electrophoretic deposition (EPD)	921:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	7	18	theme	MBG	1027:1029	arg1	ratio					1031:1035	the Cu-MBG:MBG ratio	1016:1035	the Cu-MBG:MBG ratio of the composite coatings	1016:1061	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	2	19	theme	dental	229:234	arg1	abutments					244:252	dental implant abutments	229:252	dental implant abutments	229:252	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	11	20	theme	endothelial	1764:1774	arg1	migration					1781:1789	endothelial cell migration	1764:1789	endothelial cell migration	1764:1789	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	5	21	theme	Cu	691:692	arg1	Cu					691:692	Cu	691:692	Cu	691:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	5	21	theme	Cu	691:692	arg1	amounts					680:686	various amounts	672:686	various amounts of Cu	672:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	0	22	theme	Antibacterial	77:89	arg1	Properties					91:100	Angiogenic and Antibacterial Properties	62:100	Angiogenic and Antibacterial Properties	62:100	Tailoring Copper-Doped Bioactive Glass/Chitosan Coatings with Angiogenic and Antibacterial Properties.					
35272498	13	23	theme	deposition	2090:2099	arg1	technique					2101:2109	the electrophoretic deposition technique	2070:2109	the electrophoretic deposition technique	2070:2109	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	7	24	theme	Cu-MBG	1020:1025	arg1	ratio					1031:1035	the Cu-MBG:MBG ratio	1016:1035	the Cu-MBG:MBG ratio of the composite coatings	1016:1061	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	1	25	theme	drugs	187:191	arg1	delivery					175:182	delivery	175:182	delivery of drugs	175:191	Implant coatings are frequently applied to modulate tissue response and delivery of drugs.					
35272498	1	25	theme	drugs	187:191	arg1	response					162:169	tissue response	155:169	tissue response	155:169	Implant coatings are frequently applied to modulate tissue response and delivery of drugs.					
35272498	14	26	theme	processing	2144:2153	arg1	conditions					2155:2164	the flexibility and mild processing conditions	2119:2164	the flexibility and mild processing conditions of this technique	2119:2182	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	13	27	theme	ions	2059:2062	arg1	release					2012:2018	the release	2008:2018	the release of angiogenic and antibacterial copper ions	2008:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	6	28	theme	electrophoretic	970:984	arg1	EPD					998:1000	EPD	998:1000	EPD	998:1000	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	6	28	theme	electrophoretic	970:984	arg1	deposition					986:995	electrophoretic deposition	970:995	electrophoretic deposition (EPD)	970:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	9	29	theme	migration	1303:1311	arg1	highest					1399:1405	highest	1399:1405	highest	1399:1405	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	29	theme	migration	1303:1311	arg1	rate					1313:1316	The migration rate	1299:1316	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings	1299:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	1	30	theme	Implant	103:109	arg1	coatings					111:118	Implant coatings	103:118	Implant coatings	103:118	Implant coatings are frequently applied to modulate tissue response and delivery of drugs.					
35272498	4	31	theme	coating	487:493	arg1	method					506:511	a bottom-up coating deposition method	475:511	a bottom-up coating deposition method based on nanoparticle assembly	475:542	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	3	32	theme	Cu	387:388	arg1	loading					390:396	Cu loading	387:396	Cu loading	387:396	However, precise control over Cu loading and release kinetics remains a major challenge.					
35272498	4	33	theme	local	557:561	arg1	release					563:569	local release	557:569	local release of Cu ions from implant surfaces	557:602	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	0	34	theme	Bioactive	23:31	arg1	Coatings					48:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Tailoring Copper-Doped Bioactive Glass/Chitosan Coatings with Angiogenic and Antibacterial Properties.					
35272498	9	35	theme	umbilical	1327:1335	arg1	cells					1354:1358	human umbilical vein endothelial cells	1321:1358	human umbilical vein endothelial cells cultured on the composite coatings	1321:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	6	36	theme	composite	844:852	arg1	coatings					854:861	composite coatings	844:861	composite coatings	844:861	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	7	37	theme	coating	1125:1131	arg1	properties					1133:1142	other coating properties	1119:1142	other coating properties	1119:1142	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	9	38	theme	endothelial	1342:1352	arg1	cells					1354:1358	human umbilical vein endothelial cells	1321:1358	human umbilical vein endothelial cells cultured on the composite coatings	1321:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	12	39	theme	major	1902:1906	arg1	challenge					1908:1916	a major challenge	1900:1916	a major challenge for implant coatings	1900:1937	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	2	40	from	coatings	217:224	arg1	abutments					244:252	dental implant abutments	229:252	dental implant abutments	229:252	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	0	41	theme	Angiogenic	62:71	arg1	Properties					91:100	Angiogenic and Antibacterial Properties	62:100	Angiogenic and Antibacterial Properties	62:100	Tailoring Copper-Doped Bioactive Glass/Chitosan Coatings with Angiogenic and Antibacterial Properties.					
35272498	13	42	theme	copper	2052:2057	arg1	ions					2059:2062	angiogenic and antibacterial copper ions	2023:2062	angiogenic and antibacterial copper ions	2023:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	14	43	used	used	2208:2211	arg2	method					2189:2194	our method	2185:2194	our method	2185:2194	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	12	44	theme	therapeutic	1873:1883	arg1	agents					1885:1890	therapeutic agents	1873:1890	therapeutic agents	1873:1890	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	10	45	theme	gingivalis	1565:1574	arg1	growth					1541:1546	the growth	1537:1546	the growth of Porphyromonas gingivalis up to fivefold	1537:1589	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
35272498	11	46	theme	dental	1733:1738	arg1	implants					1740:1747	dental implants	1733:1747	dental implants	1733:1747	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	6	47	theme	Cu-doped	728:735	arg1	Cu-MBG					742:747	Cu-MBG	742:747	Cu-MBG	742:747	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	6	47	theme	Cu-doped	728:735	arg1	MBG					737:739	these Cu-doped MBG	722:739	these Cu-doped MBG (Cu-MBG)	722:748	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	6	48	theme	model	902:906	arg1	surfaces					908:915	model surfaces	902:915	model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD)	902:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	12	49	theme	statement	1827:1835	arg1	control					1845:1851	Impact statement Precise control	1820:1851	Impact statement Precise control over the release of therapeutic agents	1820:1890	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	7	50	theme	release	1085:1091	arg1	kinetics					1093:1100	the Cu release kinetics	1078:1100	the Cu release kinetics	1078:1100	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	5	51	theme	glass	641:645	arg1	nanoparticles					653:665	mesoporous bioactive glass (MBG) nanoparticles	620:665	mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu	620:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	4	52	theme	ions	577:580	arg1	release					563:569	local release	557:569	local release of Cu ions from implant surfaces	557:602	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	14	53	theme	other	2228:2232	arg1	agents					2246:2251	other therapeutic agents	2228:2251	other therapeutic agents	2228:2251	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	8	54	with	coatings	1222:1229	arg1	Cu					1258:1259	Cu	1258:1259	Cu	1258:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	8	54	with	coatings	1222:1229	arg1	amount					1248:1253	the highest amount	1236:1253	the highest amount of Cu	1236:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	13	55	theme	cost-effective	1981:1994	arg1	way					1996:1998	a simple and cost-effective way	1968:1998	a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions	1968:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	6	56	theme	pure	879:882	arg1	disks					893:897	commercially pure titanium disks	866:897	commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD)	866:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	4	57	theme	implant	587:593	arg1	surfaces					595:602	implant surfaces	587:602	implant surfaces	587:602	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	5	58	theme	mesoporous	620:629	arg1	glass					641:645	mesoporous bioactive glass	620:645	mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu	620:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	5	58	theme	mesoporous	620:629	arg1	MBG					648:650	MBG	648:650	MBG	648:650	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	2	59	theme	tissue	289:294	arg1	integration					296:306	soft tissue integration	284:306	soft tissue integration	284:306	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	9	60	theme	equal	1430:1434	arg1	Cu-free					1458:1464	Cu-free	1458:1464	Cu-free	1458:1464	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	60	theme	equal	1430:1434	arg1	Cu-MBG					1447:1452	Cu-MBG	1447:1452	Cu-MBG	1447:1452	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	60	theme	equal	1430:1434	arg1	amounts					1436:1442	equal amounts	1430:1442	equal amounts of Cu-MBG and Cu-free MBG	1430:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	8	61	theme	Human	1145:1149	arg1	fibroblasts					1160:1170	Human gingival fibroblasts	1145:1170	Human gingival fibroblasts	1145:1170	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	7	62	theme	coatings	1054:1061	arg1	ratio					1031:1035	the Cu-MBG:MBG ratio	1016:1035	the Cu-MBG:MBG ratio of the composite coatings	1016:1061	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	10	63	theme	uncoated	1605:1612	arg1	implants					1614:1621	uncoated implants	1605:1621	uncoated implants	1605:1621	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
35272498	6	64	theme	Cu-free	751:757	arg1	nanoparticles					763:775	Cu-free MBG nanoparticles	751:775	Cu-free MBG nanoparticles	751:775	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	6	65	theme	bone	948:951	arg1	implants					953:960	bone implants	948:960	bone implants through electrophoretic deposition (EPD)	948:1001	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	8	66	theme	composite	1192:1200	arg1	coatings					1202:1209	the composite coatings	1188:1209	the composite coatings	1188:1209	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	8	67	theme	Cu	1258:1259	arg1	Cu					1258:1259	Cu	1258:1259	Cu	1258:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	8	67	theme	Cu	1258:1259	arg1	amount					1248:1253	the highest amount	1236:1253	the highest amount of Cu	1236:1259	Human gingival fibroblasts proliferated on the composite coatings except for coatings with the highest amount of Cu, which inhibited their proliferation.					
35272498	14	68	theme	technique	2174:2182	arg1	conditions					2155:2164	the flexibility and mild processing conditions	2119:2164	the flexibility and mild processing conditions of this technique	2119:2182	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	5	69	theme	various	672:678	arg1	Cu					691:692	Cu	691:692	Cu	691:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	5	69	theme	various	672:678	arg1	amounts					680:686	various amounts	672:686	various amounts of Cu	672:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	2	70	theme	implant	236:242	arg1	abutments					244:252	dental implant abutments	229:252	dental implant abutments	229:252	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	13	71	theme	simple	1970:1975	arg1	way					1996:1998	a simple and cost-effective way	1968:1998	a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions	1968:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	1	72	theme	tissue	155:160	arg1	response					162:169	tissue response	155:169	tissue response	155:169	Implant coatings are frequently applied to modulate tissue response and delivery of drugs.					
35272498	11	73	theme	cell	1776:1779	arg1	migration					1781:1789	endothelial cell migration	1764:1789	endothelial cell migration	1764:1789	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	4	74	theme	nanoparticle	522:533	arg1	assembly					535:542	nanoparticle assembly	522:542	nanoparticle assembly	522:542	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	11	75	theme	bacterial	1802:1810	arg1	growth					1812:1817	bacterial growth	1802:1817	bacterial growth	1802:1817	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	4	76	from	surfaces	595:602	arg1	release					563:569	local release	557:569	local release of Cu ions from implant surfaces	557:602	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	4	77	theme	bottom-up	477:485	arg1	method					506:511	a bottom-up coating deposition method	475:511	a bottom-up coating deposition method based on nanoparticle assembly	475:542	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	14	78	theme	mild	2139:2142	arg1	processing					2144:2153	mild processing	2139:2153	mild processing	2139:2153	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	12	79	theme	implant	1922:1928	arg1	coatings					1930:1937	implant coatings	1922:1937	implant coatings	1922:1937	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	3	80	theme	precise	366:372	arg1	control					374:380	precise control	366:380	precise control over Cu loading and release kinetics	366:417	However, precise control over Cu loading and release kinetics remains a major challenge.					
35272498	4	81	theme	deposition	495:504	arg1	method					506:511	a bottom-up coating deposition method	475:511	a bottom-up coating deposition method based on nanoparticle assembly	475:542	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	14	82	theme	flexibility	2123:2133	arg1	conditions					2155:2164	the flexibility and mild processing conditions	2119:2164	the flexibility and mild processing conditions of this technique	2119:2182	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	0	83	theme	Copper-Doped	10:21	arg1	Coatings					48:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Tailoring Copper-Doped Bioactive Glass/Chitosan Coatings with Angiogenic and Antibacterial Properties.					
35272498	13	84	theme	electrophoretic	2074:2088	arg1	technique					2101:2109	the electrophoretic deposition technique	2070:2109	the electrophoretic deposition technique	2070:2109	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	14	85	theme	implant	2258:2264	arg1	surfaces					2266:2273	implant surfaces	2258:2273	implant surfaces	2258:2273	Due to the flexibility and mild processing conditions of this technique, our method can also be used to incorporate other therapeutic agents onto implant surfaces.					
35272498	3	86	theme	release	402:408	arg1	kinetics					410:417	release kinetics	402:417	release kinetics	402:417	However, precise control over Cu loading and release kinetics remains a major challenge.					
35272498	0	87	theme	Glass/Chitosan	33:46	arg1	Coatings					48:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Copper-Doped Bioactive Glass/Chitosan Coatings	10:55	Tailoring Copper-Doped Bioactive Glass/Chitosan Coatings with Angiogenic and Antibacterial Properties.					
35272498	9	88	theme	human	1321:1325	arg1	cells					1354:1358	human umbilical vein endothelial cells	1321:1358	human umbilical vein endothelial cells cultured on the composite coatings	1321:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	4	89	theme	Cu	574:575	arg1	ions					577:580	Cu ions	574:580	Cu ions	574:580	In this study, we introduced a bottom-up coating deposition method based on nanoparticle assembly to allow for local release of Cu ions from implant surfaces.					
35272498	11	90	theme	nanoparticle-based	1700:1717	arg1	coatings					1719:1726	nanoparticle-based coatings	1700:1726	nanoparticle-based coatings	1700:1726	In conclusion, our data indicate that the EPD method is suitable to deposit nanoparticle-based coatings onto dental implants, which enhance endothelial cell migration and reduce bacterial growth.					
35272498	7	91	theme	other	1119:1123	arg1	properties					1133:1142	other coating properties	1119:1142	other coating properties	1119:1142	By changing the Cu-MBG:MBG ratio of the composite coatings, we controlled the Cu release kinetics without changing other coating properties.					
35272498	9	92	theme	vein	1337:1340	arg1	cells					1354:1358	human umbilical vein endothelial cells	1321:1358	human umbilical vein endothelial cells cultured on the composite coatings	1321:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	3	93	theme	major	429:433	arg1	challenge					435:443	a major challenge	427:443	a major challenge	427:443	However, precise control over Cu loading and release kinetics remains a major challenge.					
35272498	10	94	theme	Antibacterial	1471:1483	arg1	tests					1485:1489	Antibacterial tests	1471:1489	Antibacterial tests	1471:1489	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
35272498	9	95	dep	Cu-MBG	1447:1452	arg1	MBG					1466:1468	MBG	1466:1468	MBG	1466:1468	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	13	96	theme	angiogenic	2023:2032	arg1	ions					2059:2062	angiogenic and antibacterial copper ions	2023:2062	angiogenic and antibacterial copper ions	2023:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	9	97	theme	cells	1354:1358	arg1	highest					1399:1405	highest	1399:1405	highest	1399:1405	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	9	97	theme	cells	1354:1358	arg1	rate					1313:1316	The migration rate	1299:1316	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings	1299:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	12	98	theme	Precise	1837:1843	arg1	control					1845:1851	Impact statement Precise control	1820:1851	Impact statement Precise control over the release of therapeutic agents	1820:1890	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	13	99	theme	antibacterial	2038:2050	arg1	ions					2059:2062	angiogenic and antibacterial copper ions	2023:2062	angiogenic and antibacterial copper ions	2023:2062	In this study, we introduce a simple and cost-effective way to tune the release of angiogenic and antibacterial copper ions using the electrophoretic deposition technique.					
35272498	12	100	theme	agents	1885:1890	arg1	release					1862:1868	the release	1858:1868	the release of therapeutic agents	1858:1890	Impact statement Precise control over the release of therapeutic agents remains a major challenge for implant coatings.					
35272498	10	101	theme	Cu-containing	1506:1518	arg1	coatings					1520:1527	Cu-containing coatings	1506:1527	Cu-containing coatings	1506:1527	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
35272498	2	102	theme	-containing	205:215	arg1	coatings					217:224	Copper (Cu)-containing coatings	194:224	Copper (Cu)-containing coatings on dental implant abutments	194:252	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	2	103	theme	peri-implant	332:343	arg1	infections					345:354	peri-implant infections	332:354	peri-implant infections	332:354	Copper (Cu)-containing coatings on dental implant abutments have been proposed to improve soft tissue integration and reduce the risk for peri-implant infections.					
35272498	9	104	theme	composite	1376:1384	arg1	coatings					1386:1393	the composite coatings	1372:1393	the composite coatings	1372:1393	The migration rate of human umbilical vein endothelial cells cultured on the composite coatings was highest on coatings containing equal amounts of Cu-MBG and Cu-free MBG.					
35272498	6	105	theme	chitosan	801:808	arg1	solution					810:817	chitosan solution	801:817	chitosan solution	801:817	Subsequently, we suspended these Cu-doped MBG (Cu-MBG), Cu-free MBG nanoparticles, or mixtures thereof in chitosan solution and prepared a series of composite coatings on commercially pure titanium disks as model surfaces for transmucosal components of bone implants through electrophoretic deposition (EPD).					
35272498	5	106	with	nanoparticles	653:665	arg1	Cu					691:692	Cu	691:692	Cu	691:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	5	106	with	nanoparticles	653:665	arg1	amounts					680:686	various amounts	672:686	various amounts of Cu	672:692	We first doped mesoporous bioactive glass (MBG) nanoparticles with various amounts of Cu.					
35272498	10	107	theme	Porphyromonas	1551:1563	arg1	gingivalis					1565:1574	Porphyromonas gingivalis	1551:1574	Porphyromonas gingivalis	1551:1574	Antibacterial tests confirmed that Cu-containing coatings reduced the growth of Porphyromonas gingivalis up to fivefold compared with uncoated implants.					
36368100	0	0	theme	extrusion	75:83	arg1	processing					85:94	extrusion processing	75:94	extrusion processing	75:94	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	3	1	theme	docking	665:671	arg1	studies					673:679	Molecular docking studies	655:679	Molecular docking studies	655:679	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	1	2	theme	glutelin/rice	146:158	arg1	composites					167:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	2	3	theme	hydrogen	565:572	arg1	bonds					574:578	new hydrogen bonds	561:578	new hydrogen bonds	561:578	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	3	4	theme	small	808:812	arg1	sugars					824:829	glutelin and small molecular sugars	795:829	glutelin and small molecular sugars produced by starch degradation	795:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	2	5	theme	rice	485:488	arg1	starch					490:495	rice starch	485:495	rice starch	485:495	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	2	6	theme	glutelin	629:636	arg1	γ-carbons					616:624	γ-carbons	616:624	γ-carbons	616:624	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	2	6	theme	glutelin	629:636	arg1	δ-					609:610	δ-	609:610	δ-	609:610	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	1	7	theme	starch	160:165	arg1	composites					167:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	3	8	theme	molecular	814:822	arg1	sugars					824:829	glutelin and small molecular sugars	795:829	glutelin and small molecular sugars produced by starch degradation	795:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	5	9	theme	rice	1092:1095	arg1	starch					1097:1102	rice starch	1092:1102	rice starch	1092:1102	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	5	10	theme	reconstituted	1163:1175	arg1	products					1182:1189	reconstituted rice products	1163:1189	reconstituted rice products using extrusion processing	1163:1216	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	3	11	theme	glutelin	795:802	arg1	sugars					824:829	glutelin and small molecular sugars	795:829	glutelin and small molecular sugars produced by starch degradation	795:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	1	12	theme	molecular	348:356	arg1	level					358:362	the molecular level	344:362	the molecular level	344:362	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	4	13	theme	binding	1018:1024	arg1	interactions					1026:1037	these binding interactions	1012:1037	these binding interactions	1012:1037	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	5	14	theme	starch	1097:1102	arg1	mechanism					1079:1087	the interaction mechanism	1063:1087	the interaction mechanism of rice starch and glutelin	1063:1115	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	3	15	from	information	873:883	arg1	sites					896:900	binding sites	888:900	binding sites	888:900	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	4	16	theme	electron	926:933	arg1	SEM					947:949	SEM	947:949	SEM	947:949	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	4	16	theme	electron	926:933	arg1	microscopy					935:944	scanning electron microscopy	917:944	scanning electron microscopy (SEM)	917:950	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	5	17	theme	rice	1177:1180	arg1	products					1182:1189	reconstituted rice products	1163:1189	reconstituted rice products using extrusion processing	1163:1216	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	2	18	dep	carbonyl	599:606	arg1	γ-carbons					616:624	γ-carbons	616:624	γ-carbons	616:624	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	2	18	dep	carbonyl	599:606	arg1	δ-					609:610	δ-	609:610	δ-	609:610	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	5	19	theme	glutelin	1108:1115	arg1	mechanism					1079:1087	the interaction mechanism	1063:1087	the interaction mechanism of rice starch and glutelin	1063:1115	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	3	20	theme	binding	888:894	arg1	sites					896:900	binding sites	888:900	binding sites	888:900	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	2	21	theme	hydrophobic	433:443	arg1	interactions					445:456	hydrophobic interactions	433:456	hydrophobic interactions	433:456	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	3	22	theme	simultaneous	713:724	arg1	occurrence					726:735	the simultaneous occurrence	709:735	the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation	709:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	3	23	theme	reaction	778:785	arg1	occurrence					726:735	the simultaneous occurrence	709:735	the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation	709:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	0	24	theme	interaction	18:28	arg1	mechanism					30:38	the interaction mechanism	14:38	the interaction mechanism of glutelin and rice starch during extrusion processing	14:94	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	1	25	theme	interaction	274:284	arg1	mechanism					286:294	the interaction mechanism	270:294	the interaction mechanism of glutelin and rice starch	270:322	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	0	26	theme	specific	109:116	arg1	energy					129:134	specific mechanical energy	109:134	specific mechanical energy	109:134	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	4	27	theme	uniform	971:977	arg1	structures					990:999	dense and uniform flake-like structures	961:999	dense and uniform flake-like structures induced by these binding interactions	961:1037	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	1	28	theme	twin-screw	198:207	arg1	extrusion					209:217	twin-screw extrusion	198:217	twin-screw extrusion at various specific mechanical energies (SME)	198:263	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	5	29	theme	theoretical	1125:1135	arg1	references					1137:1146	theoretical references	1125:1146	theoretical references for generating reconstituted rice products using extrusion processing	1125:1216	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	4	30	theme	scanning	917:924	arg1	SEM					947:949	SEM	947:949	SEM	947:949	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	4	30	theme	scanning	917:924	arg1	microscopy					935:944	scanning electron microscopy	917:944	scanning electron microscopy (SEM)	917:950	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	2	31	theme	glutelin	409:416	arg1	structure					396:404	the structure	392:404	the structure of glutelin	392:416	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	0	32	theme	energy	129:134	arg1	role					101:104	The role	97:104	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.	0:135	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	5	33	theme	interaction	1067:1077	arg1	mechanism					1079:1087	the interaction mechanism	1063:1087	the interaction mechanism of rice starch and glutelin	1063:1115	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	4	34	theme	flake-like	979:988	arg1	structures					990:999	dense and uniform flake-like structures	961:999	dense and uniform flake-like structures induced by these binding interactions	961:1037	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	1	35	theme	glutelin	299:306	arg1	mechanism					286:294	the interaction mechanism	270:294	the interaction mechanism of glutelin and rice starch	270:322	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	0	36	theme	mechanical	118:127	arg1	energy					129:134	specific mechanical energy	109:134	specific mechanical energy	109:134	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	0	37	dep	glutelin	43:50	arg1	starch					61:66	starch	61:66	starch	61:66	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	1	38	theme	various	222:228	arg1	energies					250:257	various specific mechanical energies	222:257	various specific mechanical energies (SME)	222:263	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	1	38	theme	various	222:228	arg1	SME					260:262	SME	260:262	SME	260:262	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	2	39	theme	hydrogen	462:469	arg1	bonds					471:475	hydrogen bonds	462:475	hydrogen bonds	462:475	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	3	40	theme	Millard	744:750	arg1	reaction					752:759	the Millard reaction	740:759	the Millard reaction	740:759	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	1	41	from	energies	250:257	arg1	extrusion					209:217	twin-screw extrusion	198:217	twin-screw extrusion at various specific mechanical energies (SME)	198:263	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	5	42	theme	extrusion	1197:1205	arg1	processing					1207:1216	extrusion processing	1197:1216	extrusion processing	1197:1216	Overall, insights into the interaction mechanism of rice starch and glutelin provide theoretical references for generating reconstituted rice products using extrusion processing.					
36368100	0	43	theme	glutelin	43:50	arg1	mechanism					30:38	the interaction mechanism	14:38	the interaction mechanism of glutelin and rice starch during extrusion processing	14:94	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	1	44	theme	rice	312:315	arg1	starch					317:322	rice starch	312:322	rice starch	312:322	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	2	45	theme	new	561:563	arg1	bonds					574:578	new hydrogen bonds	561:578	new hydrogen bonds	561:578	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	3	46	theme	non-covalent	765:776	arg1	reaction					778:785	non-covalent reaction	765:785	non-covalent reaction	765:785	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	1	47	theme	starch	317:322	arg1	mechanism					286:294	the interaction mechanism	270:294	the interaction mechanism of glutelin and rice starch	270:322	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	2	48	theme	Tyr	650:652	arg1	carbonyl					599:606	the carbonyl	595:606	the carbonyl (δ- and γ-carbons of glutelin)	595:637	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	2	48	theme	Tyr	650:652	arg1	C-1					643:645	C-1	643:645	C-1 of Tyr	643:652	The results indicated that the structure of glutelin was destroyed, hydrophobic interactions and hydrogen bonds between rice starch and glutelin were formed and enhanced as the SME increased, and new hydrogen bonds were formed at the carbonyl (δ- and γ-carbons of glutelin) and C-1 of Tyr.					
36368100	3	49	theme	starch	843:848	arg1	degradation					850:860	starch degradation	843:860	starch degradation	843:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	1	50	theme	specific	230:237	arg1	energies					250:257	various specific mechanical energies	222:257	various specific mechanical energies (SME)	222:263	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	1	50	theme	specific	230:237	arg1	SME					260:262	SME	260:262	SME	260:262	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	1	51	theme	mechanical	239:248	arg1	energies					250:257	various specific mechanical energies	222:257	various specific mechanical energies (SME)	222:263	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	1	51	theme	mechanical	239:248	arg1	SME					260:262	SME	260:262	SME	260:262	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	4	52	theme	dense	961:965	arg1	structures					990:999	dense and uniform flake-like structures	961:999	dense and uniform flake-like structures induced by these binding interactions	961:1037	Additionally, scanning electron microscopy (SEM) revealed dense and uniform flake-like structures induced by these binding interactions.					
36368100	0	53	theme	rice	56:59	arg1	mechanism					30:38	the interaction mechanism	14:38	the interaction mechanism of glutelin and rice starch during extrusion processing	14:94	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	3	54	theme	Molecular	655:663	arg1	studies					673:679	Molecular docking studies	655:679	Molecular docking studies	655:679	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
36368100	0	55	dep	Insights	0:7	arg1	role					101:104	The role	97:104	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.	0:135	Insights into the interaction mechanism of glutelin and rice starch during extrusion processing: The role of specific mechanical energy.					
36368100	1	56	theme	Extruded	137:144	arg1	composites					167:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites	137:176	Extruded glutelin/rice starch composites were prepared using twin-screw extrusion at various specific mechanical energies (SME), and the interaction mechanism of glutelin and rice starch was investigated at the molecular level.					
36368100	3	57	theme	reaction	752:759	arg1	occurrence					726:735	the simultaneous occurrence	709:735	the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation	709:860	Molecular docking studies confirmed that SME promoted the simultaneous occurrence of the Millard reaction and non-covalent reaction between glutelin and small molecular sugars produced by starch degradation, providing information on binding sites.					
35032491	2	0	from	morphologies	434:445	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	3	1	theme	plasticization	765:778	arg1	process					780:786	the plasticization process	761:786	the plasticization process	761:786	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	2	2	from	soil	598:601	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	3	theme	properties	508:517	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	6	4	with	biocomposites	1216:1228	arg1	resistance					1251:1260	higher moisture resistance	1235:1260	higher moisture resistance	1235:1260	The incorporation of PHBV microparticles leads to biocomposites with higher moisture resistance.					
35032491	4	5	theme	starch	917:922	arg1	matrix					924:929	the thermoplastic starch matrix	899:929	the thermoplastic starch matrix	899:929	The microparticles were homogeneously dispersed in the thermoplastic starch matrix without suffering any deformation or breaking during the processing.					
35032491	1	6	theme	new	175:177	arg1	composites					209:218	new green and fully biodegradable composites	175:218	new green and fully biodegradable composites	175:218	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	2	7	from	crystallinity	448:460	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	1	8	theme	different	264:272	arg1	isosorbide					285:294	isosorbide	285:294	isosorbide	285:294	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	1	8	theme	different	264:272	arg1	amounts					274:280	two different amounts	260:280	two different amounts of isosorbide	260:294	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	5	9	theme	modulus	1036:1042	arg1	values					1044:1049	adequate storage modulus values	1019:1049	adequate storage modulus values	1019:1049	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	2	10	from	interactions	474:485	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	11	from	properties	508:517	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	5	12	theme	PHBV	1145:1148	arg1	microparticles					1150:1163	PHBV microparticles	1145:1163	PHBV microparticles	1145:1163	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	6	13	theme	microparticles	1192:1205	arg1	incorporation					1170:1182	The incorporation	1166:1182	The incorporation of PHBV microparticles	1166:1205	The incorporation of PHBV microparticles leads to biocomposites with higher moisture resistance.					
35032491	2	14	theme	evaluation	534:543	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	7	15	theme	time	1342:1345	arg1	period					1332:1337	a short period	1324:1337	a short period of time	1324:1345	All the biocomposites were completely biodegraded in soil in a short period of time.					
35032491	2	16	theme	microparticle	657:669	arg1	amount					671:676	microparticle amount	657:676	microparticle amount	657:676	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	17	theme	amount	671:676	arg1	function					622:629	function	622:629	function of the plasticizer and/or microparticle amount	622:676	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	1	18	theme	green	179:183	arg1	composites					209:218	new green and fully biodegradable composites	175:218	new green and fully biodegradable composites	175:218	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	2	19	theme	structural	463:472	arg1	interactions					474:485	structural interactions	463:485	structural interactions	463:485	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	4	20	theme	thermoplastic	903:915	arg1	matrix					924:929	the thermoplastic starch matrix	899:929	the thermoplastic starch matrix	899:929	The microparticles were homogeneously dispersed in the thermoplastic starch matrix without suffering any deformation or breaking during the processing.					
35032491	8	21	from	applications	1424:1435	arg1	industry					1454:1461	the packaging industry	1440:1461	the packaging industry	1440:1461	The performed study demonstrated that these biocomposites could be used for applications in the packaging industry.					
35032491	8	22	theme	packaging	1444:1452	arg1	industry					1454:1461	the packaging industry	1440:1461	the packaging industry	1440:1461	The performed study demonstrated that these biocomposites could be used for applications in the packaging industry.					
35032491	2	23	dep	plasticizer	638:648	arg1	the					634:636	the	634:636	the	634:636	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	24	theme	plasticizer	638:648	arg1	function					622:629	function	622:629	function of the plasticizer and/or microparticle amount	622:676	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	5	25	theme	storage	1028:1034	arg1	modulus					1036:1042	adequate storage modulus	1019:1042	adequate storage modulus values	1019:1049	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	3	26	theme	structural	725:734	arg1	interactions					736:747	structural interactions	725:747	structural interactions	725:747	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	2	27	theme	crystallinity	448:460	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	5	28	with	Biocomposites	1000:1012	arg1	values					1044:1049	adequate storage modulus values	1019:1049	adequate storage modulus values	1019:1049	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	0	29	dep	microparticles	92:105	arg1	behavior					123:130	behavior	123:130	behavior under environmental factors	123:158	Isosorbide plasticized corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors.					
35032491	0	29	dep	microparticles	92:105	arg1	Properties					108:117	Properties	108:117	Properties	108:117	Isosorbide plasticized corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors.					
35032491	1	30	theme	biodegradable	195:207	arg1	composites					209:218	new green and fully biodegradable composites	175:218	new green and fully biodegradable composites	175:218	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	1	31	theme	isosorbide	285:294	arg1	isosorbide					285:294	isosorbide	285:294	isosorbide	285:294	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	1	31	theme	isosorbide	285:294	arg1	amounts					274:280	two different amounts	260:280	two different amounts of isosorbide	260:294	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	2	32	theme	biodegradability	578:593	arg1	crystallinity					448:460	crystallinity	448:460	crystallinity	448:460	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	32	theme	biodegradability	578:593	arg1	interactions					474:485	structural interactions	463:485	structural interactions	463:485	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	32	theme	biodegradability	578:593	arg1	morphologies					434:445	their morphologies	428:445	their morphologies	428:445	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	32	theme	biodegradability	578:593	arg1	properties					508:517	dynamomechanical properties	491:517	dynamomechanical properties	491:517	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	32	theme	biodegradability	578:593	arg1	evaluation					534:543	the evaluation	530:543	the evaluation of their moisture resistance and biodegradability in soil	530:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	6	33	theme	higher	1235:1240	arg1	resistance					1251:1260	higher moisture resistance	1235:1260	higher moisture resistance	1235:1260	The incorporation of PHBV microparticles leads to biocomposites with higher moisture resistance.					
35032491	8	34	theme	performed	1352:1360	arg1	study					1362:1366	The performed study	1348:1366	The performed study	1348:1366	The performed study demonstrated that these biocomposites could be used for applications in the packaging industry.					
35032491	0	35	theme	corn	23:26	arg1	starch					28:33	corn starch	23:33	corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors	23:158	Isosorbide plasticized corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors.					
35032491	0	36	theme	environmental	138:150	arg1	factors					152:158	environmental factors	138:158	environmental factors	138:158	Isosorbide plasticized corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors.					
35032491	8	37	used	used	1415:1418	arg2	biocomposites					1392:1404	these biocomposites	1386:1404	these biocomposites	1386:1404	The performed study demonstrated that these biocomposites could be used for applications in the packaging industry.					
35032491	6	38	theme	moisture	1242:1249	arg1	resistance					1251:1260	higher moisture resistance	1235:1260	higher moisture resistance	1235:1260	The incorporation of PHBV microparticles leads to biocomposites with higher moisture resistance.					
35032491	2	39	theme	dynamomechanical	491:506	arg1	properties					508:517	dynamomechanical properties	491:517	dynamomechanical properties	491:517	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	40	theme	resistance	563:572	arg1	crystallinity					448:460	crystallinity	448:460	crystallinity	448:460	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	40	theme	resistance	563:572	arg1	interactions					474:485	structural interactions	463:485	structural interactions	463:485	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	40	theme	resistance	563:572	arg1	morphologies					434:445	their morphologies	428:445	their morphologies	428:445	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	40	theme	resistance	563:572	arg1	properties					508:517	dynamomechanical properties	491:517	dynamomechanical properties	491:517	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	2	40	theme	resistance	563:572	arg1	evaluation					534:543	the evaluation	530:543	the evaluation of their moisture resistance and biodegradability in soil	530:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	1	41	theme	melt	395:398	arg1	processing					400:409	melt processing	395:409	melt processing	395:409	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	5	42	dep	TPS	1081:1083	arg1	filled					1124:1129	filled	1124:1129	filled with 5 wt% of PHBV microparticles	1124:1163	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	5	42	dep	TPS	1081:1083	arg1	plasticized					1085:1095	plasticized	1085:1095	plasticized with 35% of isosorbide	1085:1118	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	2	43	theme	moisture	554:561	arg1	resistance					563:572	their moisture resistance	548:572	their moisture resistance	548:572	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	5	44	theme	microparticles	1150:1163	arg1	%					1140:1140	5 wt%	1136:1140	5 wt% of PHBV microparticles	1136:1163	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	5	44	theme	microparticles	1150:1163	arg1	microparticles					1150:1163	PHBV microparticles	1145:1163	PHBV microparticles	1145:1163	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	2	45	theme	interactions	474:485	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	1	46	theme	poly	310:313	arg1	microparticles					362:375	poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles	310:375	poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles	310:375	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	5	47	theme	isosorbide	1109:1118	arg1	isosorbide					1109:1118	isosorbide	1109:1118	isosorbide	1109:1118	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	5	47	theme	isosorbide	1109:1118	arg1	%					1104:1104	35%	1102:1104	35% of isosorbide	1102:1118	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	0	48	theme	poly	47:50	arg1	microparticles					92:105	poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles	47:105	poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors	47:158	Isosorbide plasticized corn starch filled with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microparticles: Properties and behavior under environmental factors.					
35032491	3	49	theme	melting	812:818	arg1	conditions					831:840	the melting processing conditions	808:840	the melting processing conditions used	808:845	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	2	50	from	evaluation	534:543	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	3	51	theme	processing	820:829	arg1	conditions					831:840	the melting processing conditions	808:840	the melting processing conditions used	808:845	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	3	52	theme	crystallinity	707:719	arg1	analysis					683:690	The analysis	679:690	The analysis of morphology, crystallinity and structural interactions	679:747	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	1	53	theme	corn	230:233	arg1	starch					235:240	corn starch	230:240	corn starch	230:240	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	2	54	from	analysis	416:423	arg1	soil					598:601	soil	598:601	soil	598:601	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
35032491	5	55	theme	adequate	1019:1026	arg1	modulus					1036:1042	adequate storage modulus	1019:1042	adequate storage modulus values	1019:1049	Biocomposites with adequate storage modulus values were obtained, especially the TPS plasticized with 35% of isosorbide and filled with 5 wt% of PHBV microparticles.					
35032491	3	56	theme	morphology	695:704	arg1	analysis					683:690	The analysis	679:690	The analysis of morphology, crystallinity and structural interactions	679:747	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	1	57	dep	composites	209:218	arg1	filled					300:305	filled	300:305	filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles	300:375	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	1	57	dep	composites	209:218	arg1	plasticized					243:253	plasticized	243:253	plasticized with two different amounts of isosorbide	243:294	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	1	57	dep	composites	209:218	arg1	based					221:225	based	221:225	based on corn starch	221:240	In this work, new green and fully biodegradable composites, based on corn starch, plasticized with two different amounts of isosorbide and filled by poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microparticles, were obtained by melt processing.					
35032491	6	58	theme	PHBV	1187:1190	arg1	microparticles					1192:1205	PHBV microparticles	1187:1205	PHBV microparticles	1187:1205	The incorporation of PHBV microparticles leads to biocomposites with higher moisture resistance.					
35032491	7	59	theme	short	1326:1330	arg1	period					1332:1337	a short period	1324:1337	a short period of time	1324:1345	All the biocomposites were completely biodegraded in soil in a short period of time.					
35032491	3	60	theme	interactions	736:747	arg1	analysis					683:690	The analysis	679:690	The analysis of morphology, crystallinity and structural interactions	679:747	The analysis of morphology, crystallinity and structural interactions showed that the plasticization process was completed under the melting processing conditions used.					
35032491	2	61	theme	morphologies	434:445	arg1	analysis					416:423	The analysis	412:423	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil,	412:602	The analysis of their morphologies, crystallinity, structural interactions and dynamomechanical properties as well as the evaluation of their moisture resistance and biodegradability in soil, were performed in function of the plasticizer and/or microparticle amount.					
36241260	0	0	theme	muscle	95:100	arg1	engineering					109:119	smooth muscle tissue engineering	88:119	smooth muscle tissue engineering	88:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	1	1	theme	tissues	182:188	arg1	Reconstruction					122:135	Reconstruction	122:135	Reconstruction of multilayered and functional smooth muscle tissues	122:188	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	4	2	theme	pure	644:647	arg1	scaffolds					655:663	pure CS/SF scaffolds	644:663	pure CS/SF scaffolds	644:663	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	0	3	theme	smooth	88:93	arg1	engineering					109:119	smooth muscle tissue engineering	88:119	smooth muscle tissue engineering	88:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	2	4	theme	mechanical	407:416	arg1	properties					418:427	limited mechanical properties	399:427	limited mechanical properties	399:427	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	7	5	theme	tissue	1225:1230	arg1	engineering					1232:1242	smooth muscle tissue engineering	1211:1242	smooth muscle tissue engineering	1211:1242	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	3	6	theme	extracellular	454:466	arg1	matrix					468:473	the natural extracellular matrix	442:473	the natural extracellular matrix	442:473	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	0	7	theme	tissue	102:107	arg1	engineering					109:119	smooth muscle tissue engineering	88:119	smooth muscle tissue engineering	88:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	6	8	theme	cells	1005:1009	arg1	proliferation					957:969	proliferation	957:969	proliferation	957:969	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	6	8	theme	cells	1005:1009	arg1	infiltration					975:986	infiltration	975:986	infiltration	975:986	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	4	9	theme	cell	795:798	arg1	adhesion					800:807	cell adhesion	795:807	cell adhesion	795:807	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	2	10	from	advantages	243:252	arg1	regeneration					282:293	three-dimensional tissue regeneration	257:293	three-dimensional tissue regeneration owing to the interconnected macroporous structure	257:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	5	11	from	increase	920:927	arg1	modulus					944:950	compressive modulus	932:950	compressive modulus	932:950	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	7	12	theme	smooth	1211:1216	arg1	engineering					1232:1242	smooth muscle tissue engineering	1211:1242	smooth muscle tissue engineering	1211:1242	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	5	13	theme	compressive	932:942	arg1	modulus					944:950	compressive modulus	932:950	compressive modulus	932:950	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	4	14	theme	pore	734:737	arg1	size					739:742	pore size	734:742	pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation	734:825	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	4	15	theme	CS/SF	649:653	arg1	scaffolds					655:663	pure CS/SF scaffolds	644:663	pure CS/SF scaffolds	644:663	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	6	16	theme	smooth	991:996	arg1	SMCs					1012:1015	SMCs	1012:1015	SMCs	1012:1015	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	6	16	theme	smooth	991:996	arg1	cells					1005:1009	smooth muscle cells	991:1009	smooth muscle cells (SMCs)	991:1016	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	5	17	theme	mechanical	869:878	arg1	properties					880:889	the mechanical properties	865:889	the mechanical properties of scaffolds	865:902	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	2	18	theme	macroporous	323:333	arg1	structure					335:343	the interconnected macroporous structure	304:343	the interconnected macroporous structure	304:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	0	19	theme	fibroin	14:20	arg1	biomimic					22:29	Chitosan/silk fibroin biomimic	0:29	Chitosan/silk fibroin biomimic	0:29	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	6	20	theme	muscle	998:1003	arg1	SMCs					1012:1015	SMCs	1012:1015	SMCs	1012:1015	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	6	20	theme	muscle	998:1003	arg1	cells					1005:1009	smooth muscle cells	991:1009	smooth muscle cells (SMCs)	991:1016	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	3	21	theme	electrospun	494:504	arg1	NFs					518:520	NFs	518:520	NFs	518:520	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	3	21	theme	electrospun	494:504	arg1	nanofibers					506:515	cellulose acetate electrospun nanofibers	476:515	cellulose acetate electrospun nanofibers (NFs)	476:521	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	0	22	theme	Chitosan/silk	0:12	arg1	biomimic					22:29	Chitosan/silk fibroin biomimic	0:29	Chitosan/silk fibroin biomimic	0:29	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	5	23	theme	six-fold	911:918	arg1	increase					920:927	a six-fold increase	909:927	a six-fold increase in compressive modulus	909:950	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	6	24	theme	nanofibers	1065:1074	arg1	existence					1052:1060	the existence	1048:1060	the existence of nanofibers	1048:1074	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	1	25	dep	challenge	200:208	arg1	nowadays					210:217	nowadays	210:217	nowadays	210:217	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	7	26	theme	muscle	1218:1223	arg1	engineering					1232:1242	smooth muscle tissue engineering	1211:1242	smooth muscle tissue engineering	1211:1242	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	4	27	theme	roughened	703:711	arg1	surface					713:719	roughened surface	703:719	roughened surface	703:719	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	3	28	theme	cryogel	574:580	arg1	scaffolds					582:590	chitosan/silk fibroin (CS/SF) cryogel scaffolds	544:590	chitosan/silk fibroin (CS/SF) cryogel scaffolds	544:590	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	2	29	contain	possess	229:235	arg2	advantages					243:252	great advantages	237:252	great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure	237:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	2	29	contain	possess	229:235	arg1	Cryogels					220:227	Cryogels	220:227	Cryogels	220:227	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	3	30	theme	cellulose	476:484	arg1	NFs					518:520	NFs	518:520	NFs	518:520	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	3	30	theme	cellulose	476:484	arg1	nanofibers					506:515	cellulose acetate electrospun nanofibers	476:515	cellulose acetate electrospun nanofibers (NFs)	476:521	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	7	31	theme	genes	1174:1178	arg1	expression					1140:1149	higher expression	1133:1149	higher expression of contraction-related genes	1133:1178	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	3	32	theme	acetate	486:492	arg1	NFs					518:520	NFs	518:520	NFs	518:520	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	3	32	theme	acetate	486:492	arg1	nanofibers					506:515	cellulose acetate electrospun nanofibers	476:515	cellulose acetate electrospun nanofibers (NFs)	476:521	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	6	33	dep	proliferation	957:969	arg1	The					953:955	The	953:955	The	953:955	The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers.					
36241260	2	34	theme	tissue	275:280	arg1	regeneration					282:293	three-dimensional tissue regeneration	257:293	three-dimensional tissue regeneration owing to the interconnected macroporous structure	257:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	0	35	theme	acetate	65:71	arg1	nanofibers					73:82	cellulose acetate nanofibers	55:82	cellulose acetate nanofibers for smooth muscle tissue engineering	55:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	5	36	theme	scaffolds	894:902	arg1	properties					880:889	the mechanical properties	865:889	the mechanical properties of scaffolds	865:902	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	2	37	theme	three-dimensional	257:273	arg1	regeneration					282:293	three-dimensional tissue regeneration	257:293	three-dimensional tissue regeneration owing to the interconnected macroporous structure	257:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	2	38	theme	limited	399:405	arg1	properties					418:427	limited mechanical properties	399:427	limited mechanical properties	399:427	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	0	39	theme	cellulose	55:63	arg1	nanofibers					73:82	cellulose acetate nanofibers	55:82	cellulose acetate nanofibers for smooth muscle tissue engineering	55:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	7	40	theme	contraction-related	1154:1172	arg1	genes					1174:1178	contraction-related genes	1154:1178	contraction-related genes	1154:1178	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	2	41	theme	great	237:241	arg1	advantages					243:252	great advantages	237:252	great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure	237:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	1	42	theme	multilayered	140:151	arg1	tissues					182:188	multilayered and functional smooth muscle tissues	140:188	multilayered and functional smooth muscle tissues	140:188	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	7	43	theme	higher	1133:1138	arg1	expression					1140:1149	higher expression	1133:1149	higher expression of contraction-related genes	1133:1178	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	2	44	theme	interconnected	308:321	arg1	structure					335:343	the interconnected macroporous structure	304:343	the interconnected macroporous structure	304:343	Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties.					
36241260	0	45	dep	scaffolds	31:39	arg1	reinforced					41:50	reinforced	41:50	scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering	31:119	Chitosan/silk fibroin biomimic scaffolds reinforced by cellulose acetate nanofibers for smooth muscle tissue engineering.					
36241260	7	46	theme	CS/SF/NFs	1103:1111	arg1	scaffolds					1113:1121	CS/SF/NFs scaffolds	1103:1121	CS/SF/NFs scaffolds	1103:1121	Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.					
36241260	4	47	theme	CS/SF/NFs	666:674	arg1	scaffolds					686:694	CS/SF/NFs composite scaffolds	666:694	CS/SF/NFs composite scaffolds	666:694	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	4	48	dep	size	739:742	arg1	263.1 ± 75.7 μm					765:779	263.1 ± 75.7 μm	765:779	263.1 ± 75.7 μm	765:779	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	4	48	dep	size	739:742	arg1	216.2 ± 65.3 μm					745:759	216.2 ± 65.3 μm	745:759	216.2 ± 65.3 μm	745:759	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36241260	1	49	theme	functional	157:166	arg1	tissues					182:188	multilayered and functional smooth muscle tissues	140:188	multilayered and functional smooth muscle tissues	140:188	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	1	50	theme	smooth	168:173	arg1	tissues					182:188	multilayered and functional smooth muscle tissues	140:188	multilayered and functional smooth muscle tissues	140:188	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	3	51	theme	natural	446:452	arg1	matrix					468:473	the natural extracellular matrix	442:473	the natural extracellular matrix	442:473	Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.					
36241260	5	52	theme	nanofibers	845:854	arg1	Incorporation					828:840	Incorporation	828:840	Incorporation of nanofibers	828:854	Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus.					
36241260	1	53	theme	muscle	175:180	arg1	tissues					182:188	multilayered and functional smooth muscle tissues	140:188	multilayered and functional smooth muscle tissues	140:188	Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays.					
36241260	4	54	theme	composite	676:684	arg1	scaffolds					686:694	CS/SF/NFs composite scaffolds	666:694	CS/SF/NFs composite scaffolds	666:694	Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation.					
36040454	0	0	theme	neuromorphic	88:99	arg1	computing					101:109	neuromorphic computing	88:109	neuromorphic computing	88:109	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	4	1	theme	conductance	550:560	arg1	tuning					562:567	linear conductance tuning	543:567	linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors	543:744	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	7	2	theme	computational	1113:1125	arg1	applications					1163:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	This work verifies the feasibility of using biopolymers for future high-performance computational and wearable/implantable electronic applications.					
36040454	4	3	theme	analog	728:733	arg1	memristors					735:744	previously reported biomaterial-based analog memristors	690:744	previously reported biomaterial-based analog memristors	690:744	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	6	4	theme	ideal	998:1002	arg1	device					1013:1018	an ideal synaptic device	995:1018	an ideal synaptic device (95.7%)	995:1026	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	4	theme	ideal	998:1002	arg1	%					1025:1025	95.7%	1021:1025	95.7%	1021:1025	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	5	5	theme	Ag	800:801	arg1	filaments					803:811	Ag filaments	800:811	Ag filaments	800:811	AgNO3 is doped to ι-car to suppress the formation of Ag filaments, thereby eliminating uneven Joule heating.					
36040454	4	6	theme	biomaterial-based	710:726	arg1	memristors					735:744	previously reported biomaterial-based analog memristors	690:744	previously reported biomaterial-based analog memristors	690:744	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	7	theme	conduction	615:624	arg1	>2000					634:638	>2000	634:638	>2000	634:638	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	7	theme	conduction	615:624	arg1	states					626:631	more enriched conduction states	601:631	more enriched conduction states (>2000)	601:639	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	6	8	theme	doping-enhanced	920:934	arg1	accuracy					948:955	a doping-enhanced recognition accuracy	918:955	a doping-enhanced recognition accuracy (93.8%)	918:963	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	8	theme	doping-enhanced	920:934	arg1	%					962:962	93.8%	958:962	93.8%	958:962	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	7	9	theme	future	1089:1094	arg1	applications					1163:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	This work verifies the feasibility of using biopolymers for future high-performance computational and wearable/implantable electronic applications.					
36040454	7	10	theme	high-performance	1096:1111	arg1	applications					1163:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	This work verifies the feasibility of using biopolymers for future high-performance computational and wearable/implantable electronic applications.					
36040454	1	11	theme	promising	151:159	arg1	method					161:166	a promising method	149:166	a promising method for resolving the traditional von Neumann bottleneck	149:219	Neuromorphic computing is considered a promising method for resolving the traditional von Neumann bottleneck.					
36040454	1	12	theme	traditional	186:196	arg1	bottleneck					210:219	the traditional von Neumann bottleneck	182:219	the traditional von Neumann bottleneck	182:219	Neuromorphic computing is considered a promising method for resolving the traditional von Neumann bottleneck.					
36040454	7	13	theme	electronic	1152:1161	arg1	applications					1163:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	This work verifies the feasibility of using biopolymers for future high-performance computational and wearable/implantable electronic applications.					
36040454	4	14	theme	linear	543:548	arg1	tuning					562:567	linear conductance tuning	543:567	linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors	543:744	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	3	15	theme	based	454:458	arg1	memristor					460:468	iota-carrageenan (ι-car) based memristor	429:468	iota-carrageenan (ι-car) based memristor	429:468	In this work, a AgNO3 doped iota-carrageenan (ι-car) based memristor is proposed to resolve the non-linear limitation.					
36040454	1	16	theme	von	198:200	arg1	bottleneck					210:219	the traditional von Neumann bottleneck	182:219	the traditional von Neumann bottleneck	182:219	Neuromorphic computing is considered a promising method for resolving the traditional von Neumann bottleneck.					
36040454	0	17	theme	based	11:15	arg1	synapses					28:35	Biopolymer based artificial synapses	0:35	Biopolymer based artificial synapses	0:35	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	2	18	theme	limited	374:380	arg1	states					393:398	limited conduction states	374:398	limited conduction states	374:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	1	19	theme	Neumann	202:208	arg1	bottleneck					210:219	the traditional von Neumann bottleneck	182:219	the traditional von Neumann bottleneck	182:219	Neuromorphic computing is considered a promising method for resolving the traditional von Neumann bottleneck.					
36040454	5	20	theme	uneven	834:839	arg1	heating					847:853	uneven Joule heating	834:853	uneven Joule heating	834:853	AgNO3 is doped to ι-car to suppress the formation of Ag filaments, thereby eliminating uneven Joule heating.					
36040454	5	21	theme	Joule	841:845	arg1	heating					847:853	uneven Joule heating	834:853	uneven Joule heating	834:853	AgNO3 is doped to ι-car to suppress the formation of Ag filaments, thereby eliminating uneven Joule heating.					
36040454	1	22	theme	Neuromorphic	112:123	arg1	computing					125:133	Neuromorphic computing	112:133	Neuromorphic computing	112:133	Neuromorphic computing is considered a promising method for resolving the traditional von Neumann bottleneck.					
36040454	4	23	theme	power	657:661	arg1	consumption					663:673	much lower power consumption	646:673	much lower power consumption (∼3.6 μW)	646:683	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	23	theme	power	657:661	arg1	μW					681:682	∼3.6 μW	676:682	∼3.6 μW	676:682	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	0	24	theme	artificial	17:26	arg1	synapses					28:35	Biopolymer based artificial synapses	0:35	Biopolymer based artificial synapses	0:35	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	4	25	theme	enriched	606:613	arg1	>2000					634:638	>2000	634:638	>2000	634:638	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	25	theme	enriched	606:613	arg1	states					626:631	more enriched conduction states	601:631	more enriched conduction states (>2000)	601:639	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	2	26	theme	poor	355:358	arg1	linearity					360:368	poor linearity	355:368	poor linearity	355:368	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	4	27	theme	lower	651:655	arg1	consumption					663:673	much lower power consumption	646:673	much lower power consumption (∼3.6 μW)	646:683	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	27	theme	lower	651:655	arg1	μW					681:682	∼3.6 μW	676:682	∼3.6 μW	676:682	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	0	28	theme	linear	44:49	arg1	tuning					63:68	linear conductance tuning	44:68	linear conductance tuning	44:68	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	6	29	theme	digits	892:897	arg1	learning					867:874	deep learning	862:874	deep learning of hand-written digits	862:897	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	29	theme	digits	892:897	arg1	application					905:915	an application	902:915	an application	902:915	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	5	30	theme	filaments	803:811	arg1	formation					787:795	the formation	783:795	the formation of Ag filaments	783:811	AgNO3 is doped to ι-car to suppress the formation of Ag filaments, thereby eliminating uneven Joule heating.					
36040454	6	31	theme	hand-written	879:890	arg1	digits					892:897	hand-written digits	879:897	hand-written digits	879:897	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	2	32	theme	popular	272:278	arg1	synapses					259:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	32	theme	popular	272:278	arg1	units					280:284	popular units	272:284	popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states	272:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	3	33	theme	non-linear	497:506	arg1	limitation					508:517	the non-linear limitation	493:517	the non-linear limitation	493:517	In this work, a AgNO3 doped iota-carrageenan (ι-car) based memristor is proposed to resolve the non-linear limitation.					
36040454	7	34	theme	wearable/implantable	1131:1150	arg1	applications					1163:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	future high-performance computational and wearable/implantable electronic applications	1089:1174	This work verifies the feasibility of using biopolymers for future high-performance computational and wearable/implantable electronic applications.					
36040454	4	35	theme	higher	576:581	arg1	∼104					594:597	∼104	594:597	∼104	594:597	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	35	theme	higher	576:581	arg1	endurance					583:591	a higher endurance	574:591	a higher endurance (∼104)	574:598	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	0	36	theme	conductance	51:61	arg1	tuning					63:68	linear conductance tuning	44:68	linear conductance tuning	44:68	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	2	37	theme	artificial	248:257	arg1	synapses					259:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	37	theme	artificial	248:257	arg1	units					280:284	popular units	272:284	popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states	272:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	6	38	theme	deep	862:865	arg1	learning					867:874	deep learning	862:874	deep learning of hand-written digits	862:897	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	38	theme	deep	862:865	arg1	application					905:915	an application	902:915	an application	902:915	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	2	39	theme	biomaterial-based	230:246	arg1	synapses					259:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	39	theme	biomaterial-based	230:246	arg1	units					280:284	popular units	272:284	popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states	272:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	40	theme	computing	316:324	arg1	systems					326:332	neuromorphic computing systems	303:332	neuromorphic computing systems	303:332	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	4	41	with	tuning	562:567	arg1	>2000					634:638	>2000	634:638	>2000	634:638	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	41	with	tuning	562:567	arg1	consumption					663:673	much lower power consumption	646:673	much lower power consumption (∼3.6 μW)	646:683	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	41	with	tuning	562:567	arg1	endurance					583:591	a higher endurance	574:591	a higher endurance (∼104)	574:598	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	41	with	tuning	562:567	arg1	μW					681:682	∼3.6 μW	676:682	∼3.6 μW	676:682	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	41	with	tuning	562:567	arg1	∼104					594:597	∼104	594:597	∼104	594:597	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	4	41	with	tuning	562:567	arg1	states					626:631	more enriched conduction states	601:631	more enriched conduction states (>2000)	601:639	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	6	42	theme	recognition	936:946	arg1	accuracy					948:955	a doping-enhanced recognition accuracy	918:955	a doping-enhanced recognition accuracy (93.8%)	918:963	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	42	theme	recognition	936:946	arg1	%					962:962	93.8%	958:962	93.8%	958:962	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	2	43	theme	Natural	222:228	arg1	synapses					259:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses	222:266	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	43	theme	Natural	222:228	arg1	units					280:284	popular units	272:284	popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states	272:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	44	theme	neuromorphic	303:314	arg1	systems					326:332	neuromorphic computing systems	303:332	neuromorphic computing systems	303:332	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	2	45	theme	conduction	382:391	arg1	states					393:398	limited conduction states	374:398	limited conduction states	374:398	Natural biomaterial-based artificial synapses are popular units for constructing neuromorphic computing systems while suffering from poor linearity and limited conduction states.					
36040454	0	46	dep	based	11:15	arg1	Biopolymer					0:9	Biopolymer	0:9	Biopolymer	0:9	Biopolymer based artificial synapses enable linear conductance tuning and low-power for neuromorphic computing.					
36040454	4	47	theme	reported	701:708	arg1	memristors					735:744	previously reported biomaterial-based analog memristors	690:744	previously reported biomaterial-based analog memristors	690:744	The memristor presents linear conductance tuning with a higher endurance (∼104), more enriched conduction states (>2000), and much lower power consumption (∼3.6 μW) than previously reported biomaterial-based analog memristors.					
36040454	6	48	theme	synaptic	1004:1011	arg1	device					1013:1018	an ideal synaptic device	995:1018	an ideal synaptic device (95.7%)	995:1026	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
36040454	6	48	theme	synaptic	1004:1011	arg1	%					1025:1025	95.7%	1021:1025	95.7%	1021:1025	Using deep learning of hand-written digits as an application, a doping-enhanced recognition accuracy (93.8%) is achieved, close to that of an ideal synaptic device (95.7%).					
35863928	6	0	theme	Relative	940:947	arg1	analysis					962:969	Relative quantitative analysis	940:969	Relative quantitative analysis	940:969	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	5	1	theme	online	909:914	arg1	spectrometry					926:937	online HPLC-mass spectrometry	909:937	online HPLC-mass spectrometry	909:937	The isomers were then qualitatively and quantitatively compared at different lactation stages using online HPLC-mass spectrometry.					
35863928	2	2	from	abundant	319:326	arg1	milk					336:339	goat milk	331:339	goat milk	331:339	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	6	3	theme	isomers	1029:1035	arg1	content					993:999	the total content	983:999	the total content of the 5 galactosyl lactose isomers	983:1035	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	6	3	theme	isomers	1029:1035	arg1	highest					1041:1047	highest	1041:1047	highest	1041:1047	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	0	4	theme	isomers	95:101	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	9	5	theme	2	1312:1312	arg1	times					1314:1318	times	1314:1318	times	1314:1318	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	10	6	from	isomers	1558:1564	arg1	colostrum					1569:1577	colostrum	1569:1577	colostrum (32.3 mg/L)	1569:1589	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	6	from	isomers	1558:1564	arg1	mg/L					1585:1588	32.3 mg/L	1580:1588	32.3 mg/L	1580:1588	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	5	7	theme	HPLC-mass	916:924	arg1	spectrometry					926:937	online HPLC-mass spectrometry	909:937	online HPLC-mass spectrometry	909:937	The isomers were then qualitatively and quantitatively compared at different lactation stages using online HPLC-mass spectrometry.					
35863928	2	8	from	milk	336:339	arg1	abundant					319:326	abundant	319:326	abundant	319:326	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	6	9	theme	lactose	1021:1027	arg1	isomers					1029:1035	the 5 galactosyl lactose isomers	1004:1035	the 5 galactosyl lactose isomers	1004:1035	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	3	10	theme	goat	449:452	arg1	lactose					470:476	goat milk galactosyl lactose	449:476	goat milk galactosyl lactose	449:476	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	11	11	from	lactose	1822:1828	arg1	milk					1838:1841	goat milk	1833:1841	goat milk	1833:1841	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	3	12	dep	separated	483:491	arg1	lactose					583:589	β4'-galactosyl lactose	568:589	β4'-galactosyl lactose (β4'-GL)	568:598	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	lactose					616:622	α3'-galactosyl lactose	601:622	α3'-galactosyl lactose (α3'-GL)	601:631	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	lactose					517:523	β6'-galactosyl lactose	502:523	β6'-galactosyl lactose (β6'-GL)	502:532	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	lactose					550:556	α6'-galactosyl lactose	535:556	α6'-galactosyl lactose (α6'-GL)	535:565	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	lactose					653:659	β3'-galactosyl lactose	638:659	β3'-galactosyl lactose (β3'-GL)	638:668	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	α3'-GL					625:630	α3'-GL	625:630	α3'-GL	625:630	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	α6'-GL					559:564	α6'-GL	559:564	α6'-GL	559:564	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	β3'-GL					662:667	β3'-GL	662:667	β3'-GL	662:667	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	β4'-GL					592:597	β4'-GL	592:597	β4'-GL	592:597	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	12	dep	separated	483:491	arg1	β6'-GL					526:531	β6'-GL	526:531	β6'-GL	526:531	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	6	13	theme	galactosyl	1010:1019	arg1	isomers					1029:1035	the 5 galactosyl lactose isomers	1004:1035	the 5 galactosyl lactose isomers	1004:1035	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	0	14	theme	goat	108:111	arg1	milk					113:116	goat milk	108:116	goat milk	108:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	4	15	theme	galactooligosaccharide	720:741	arg1	products					743:750	commercial galactooligosaccharide products	709:750	commercial galactooligosaccharide products	709:750	This composition differs from that of commercial galactooligosaccharide products, which comprise mainly β-configuration oligosaccharides.					
35863928	0	16	theme	different	121:129	arg1	stages					141:146	different lactation stages	121:146	different lactation stages	121:146	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	10	17	theme	transitional	1628:1639	arg1	mg/L					1652:1655	88.1 mg/L	1647:1655	88.1 mg/L	1647:1655	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	17	theme	transitional	1628:1639	arg1	milk					1641:1644	transitional milk	1628:1644	transitional milk (88.1 mg/L)	1628:1656	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	2	18	theme	galactosyl	297:306	arg1	lactose					308:314	galactosyl lactose	297:314	galactosyl lactose	297:314	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	1	19	theme	galactosyl	196:205	arg1	lactose					207:213	galactosyl lactose	196:213	galactosyl lactose	196:213	Galactooligosaccharides are composed mainly of galactosyl lactose, which is important for infant growth and as a functional food additive.					
35863928	0	20	from	comparison	47:56	arg1	milk					113:116	goat milk	108:116	goat milk	108:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	11	21	from	structure	1785:1793	arg1	milk					1838:1841	goat milk	1833:1841	goat milk	1833:1841	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	11	22	theme	quantitative	1723:1734	arg1	basis					1736:1740	an important quantitative basis	1710:1740	an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food	1710:1891	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	7	23	theme	main	1105:1108	arg1	β3'-GL					1090:1095	β3'-GL	1090:1095	β3'-GL	1090:1095	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	7	23	theme	main	1105:1108	arg1	isomer					1110:1115	the main isomer	1101:1115	the main isomer in colostrum	1101:1128	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	5	24	theme	different	876:884	arg1	stages					896:901	different lactation stages	876:901	different lactation stages	876:901	The isomers were then qualitatively and quantitatively compared at different lactation stages using online HPLC-mass spectrometry.					
35863928	0	25	theme	Qualitative	0:10	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	9	26	theme	α3'-GL	1293:1298	arg1	content					1300:1306	α3'-GL content	1293:1306	α3'-GL content	1293:1306	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	11	27	from	function	1799:1806	arg1	milk					1838:1841	goat milk	1833:1841	goat milk	1833:1841	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	2	28	theme	goat	331:334	arg1	milk					336:339	goat milk	331:339	goat milk	331:339	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	9	29	from	times	1314:1318	arg1	milk					1401:1404	mature milk	1394:1404	mature milk	1394:1404	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	9	29	from	times	1314:1318	arg1	colostrum					1335:1343	colostrum	1335:1343	colostrum	1335:1343	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	5	30	theme	lactation	886:894	arg1	stages					896:901	different lactation stages	876:901	different lactation stages	876:901	The isomers were then qualitatively and quantitatively compared at different lactation stages using online HPLC-mass spectrometry.					
35863928	0	31	theme	mass	29:32	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	7	32	from	isomer	1110:1115	arg1	colostrum					1120:1128	colostrum	1120:1128	colostrum	1120:1128	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	7	32	from	isomer	1110:1115	arg1	milk					1188:1191	transitional and mature milk	1164:1191	transitional and mature milk	1164:1191	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	9	33	dep	5	1448:1448	arg1	higher					1462:1467	higher	1462:1467	higher	1462:1467	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	10	34	from	milk	1669:1672	arg1	α3'-GL					1596:1601	α3'-GL	1596:1601	α3'-GL	1596:1601	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	34	from	milk	1669:1672	arg1	abundant					1616:1623	abundant	1616:1623	abundant	1616:1623	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	3	35	theme	α6'-galactosyl	535:548	arg1	lactose					550:556	α6'-galactosyl lactose	535:556	α6'-galactosyl lactose (α6'-GL)	535:565	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	35	theme	α6'-galactosyl	535:548	arg1	α6'-GL					559:564	α6'-GL	559:564	α6'-GL	559:564	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	36	theme	milk	454:457	arg1	lactose					470:476	goat milk galactosyl lactose	449:476	goat milk galactosyl lactose	449:476	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	0	37	theme	quantitative	16:27	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	11	38	theme	important	1713:1721	arg1	basis					1736:1740	an important quantitative basis	1710:1740	an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food	1710:1891	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	0	39	theme	lactation	131:139	arg1	stages					141:146	different lactation stages	121:146	different lactation stages	121:146	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	11	40	theme	lactose	1822:1828	arg1	function					1799:1806	function	1799:1806	function	1799:1806	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	11	40	theme	lactose	1822:1828	arg1	structure					1785:1793	structure	1785:1793	structure	1785:1793	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	3	41	theme	galactosyl	459:468	arg1	lactose					470:476	goat milk galactosyl lactose	449:476	goat milk galactosyl lactose	449:476	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	6	42	theme	total	987:991	arg1	content					993:999	the total content	983:999	the total content of the 5 galactosyl lactose isomers	983:1035	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	6	42	theme	total	987:991	arg1	highest					1041:1047	highest	1041:1047	highest	1041:1047	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	3	43	theme	β4'-galactosyl	568:581	arg1	β4'-GL					592:597	β4'-GL	592:597	β4'-GL	592:597	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	43	theme	β4'-galactosyl	568:581	arg1	lactose					583:589	β4'-galactosyl lactose	568:589	β4'-galactosyl lactose (β4'-GL)	568:598	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	7	44	theme	main	1149:1152	arg1	α3'-GL					1134:1139	α3'-GL	1134:1139	α3'-GL	1134:1139	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	7	44	theme	main	1149:1152	arg1	isomer					1154:1159	the main isomer	1145:1159	the main isomer in transitional and mature milk	1145:1191	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	0	45	theme	spectrometry	34:45	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	7	46	theme	transitional	1164:1175	arg1	milk					1188:1191	transitional and mature milk	1164:1191	transitional and mature milk	1164:1191	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	3	47	theme	α3'-galactosyl	601:614	arg1	α3'-GL					625:630	α3'-GL	625:630	α3'-GL	625:630	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	47	theme	α3'-galactosyl	601:614	arg1	lactose					616:622	α3'-galactosyl lactose	601:622	α3'-galactosyl lactose (α3'-GL)	601:631	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	1	48	theme	infant	239:244	arg1	growth					246:251	infant growth	239:251	infant growth	239:251	Galactooligosaccharides are composed mainly of galactosyl lactose, which is important for infant growth and as a functional food additive.					
35863928	0	49	theme	characteristic	61:74	arg1	isomers					95:101	characteristic galactosyl lactose isomers	61:101	characteristic galactosyl lactose isomers from goat milk	61:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	9	50	theme	transitional	1368:1379	arg1	milk					1381:1384	transitional milk	1368:1384	transitional milk	1368:1384	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	6	51	theme	goat	1065:1068	arg1	milk					1070:1073	transitional goat milk	1052:1073	transitional goat milk	1052:1073	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	9	52	dep	times	1314:1318	arg1	higher					1320:1325	higher	1320:1325	higher	1320:1325	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	10	53	theme	mature	1662:1667	arg1	milk					1669:1672	mature milk	1662:1672	mature milk (36.3 mg/L)	1662:1684	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	53	theme	mature	1662:1667	arg1	mg/L					1680:1683	36.3 mg/L	1675:1683	36.3 mg/L	1675:1683	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	54	theme	quantitative	1493:1504	arg1	analysis					1506:1513	Absolute quantitative analysis	1484:1513	Absolute quantitative analysis	1484:1513	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	11	55	theme	functional	1877:1886	arg1	food					1888:1891	a functional food	1875:1891	a functional food	1875:1891	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	2	56	theme	complex	346:352	arg1	structure					354:362	its complex structure	342:362	its complex structure	342:362	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	4	57	theme	β-configuration	775:789	arg1	oligosaccharides					791:806	mainly β-configuration oligosaccharides	768:806	mainly β-configuration oligosaccharides	768:806	This composition differs from that of commercial galactooligosaccharide products, which comprise mainly β-configuration oligosaccharides.					
35863928	10	58	theme	Absolute	1484:1491	arg1	analysis					1506:1513	Absolute quantitative analysis	1484:1513	Absolute quantitative analysis	1484:1513	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	3	59	theme	β3'-galactosyl	638:651	arg1	β3'-GL					662:667	β3'-GL	662:667	β3'-GL	662:667	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	59	theme	β3'-galactosyl	638:651	arg1	lactose					653:659	β3'-galactosyl lactose	638:659	β3'-galactosyl lactose (β3'-GL)	638:668	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	11	60	theme	galactosyl	1811:1820	arg1	lactose					1822:1828	galactosyl lactose	1811:1828	galactosyl lactose in goat milk	1811:1841	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	7	61	from	isomer	1154:1159	arg1	colostrum					1120:1128	colostrum	1120:1128	colostrum	1120:1128	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	7	61	from	isomer	1154:1159	arg1	milk					1188:1191	transitional and mature milk	1164:1191	transitional and mature milk	1164:1191	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	3	62	theme	lactose	470:476	arg1	isomers					438:444	5 isomers	436:444	5 isomers of goat milk galactosyl lactose	436:476	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	4	63	theme	commercial	709:718	arg1	products					743:750	commercial galactooligosaccharide products	709:750	commercial galactooligosaccharide products	709:750	This composition differs from that of commercial galactooligosaccharide products, which comprise mainly β-configuration oligosaccharides.					
35863928	6	64	theme	transitional	1052:1063	arg1	milk					1070:1073	transitional goat milk	1052:1073	transitional goat milk	1052:1073	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	8	65	dep	β6'-Galactosyl	1194:1207	arg1	lactose					1209:1215	lactose	1209:1215	lactose	1209:1215	β6'-Galactosyl lactose and β4'-GL tended to increase and then decrease during lactation.					
35863928	0	66	from	milk	113:116	arg1	isomers					95:101	characteristic galactosyl lactose isomers	61:101	characteristic galactosyl lactose isomers from goat milk	61:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	0	66	from	milk	113:116	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	11	67	from	milk	1838:1841	arg1	function					1799:1806	function	1799:1806	function	1799:1806	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	11	67	from	milk	1838:1841	arg1	structure					1785:1793	structure	1785:1793	structure	1785:1793	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	11	68	theme	goat	1833:1836	arg1	milk					1838:1841	goat milk	1833:1841	goat milk	1833:1841	These findings provide an important quantitative basis for understanding the relationship between structure and function of galactosyl lactose in goat milk, as well as its exploitation as a functional food.					
35863928	9	69	theme	mature	1394:1399	arg1	milk					1401:1404	mature milk	1394:1404	mature milk	1394:1404	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	0	70	theme	lactose	87:93	arg1	isomers					95:101	characteristic galactosyl lactose isomers	61:101	characteristic galactosyl lactose isomers from goat milk	61:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	2	71	theme	isomers	412:418	arg1	analysis					396:403	analysis	396:403	analysis	396:403	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	2	71	theme	isomers	412:418	arg1	separation					381:390	separation	381:390	separation	381:390	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	10	72	from	abundant	1616:1623	arg1	mg/L					1652:1655	88.1 mg/L	1647:1655	88.1 mg/L	1647:1655	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	72	from	abundant	1616:1623	arg1	milk					1669:1672	mature milk	1662:1672	mature milk (36.3 mg/L)	1662:1684	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	72	from	abundant	1616:1623	arg1	mg/L					1680:1683	36.3 mg/L	1675:1683	36.3 mg/L	1675:1683	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	72	from	abundant	1616:1623	arg1	milk					1641:1644	transitional milk	1628:1644	transitional milk (88.1 mg/L)	1628:1656	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	3	73	theme	β6'-galactosyl	502:515	arg1	β6'-GL					526:531	β6'-GL	526:531	β6'-GL	526:531	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	3	73	theme	β6'-galactosyl	502:515	arg1	lactose					517:523	β6'-galactosyl lactose	502:523	β6'-galactosyl lactose (β6'-GL)	502:532	In this study, 5 isomers of goat milk galactosyl lactose were separated by HPLC: β6'-galactosyl lactose (β6'-GL), α6'-galactosyl lactose (α6'-GL), β4'-galactosyl lactose (β4'-GL), α3'-galactosyl lactose (α3'-GL), and β3'-galactosyl lactose (β3'-GL).					
35863928	9	74	from	5	1448:1448	arg1	contrast					1410:1417	contrast	1410:1417	contrast	1410:1417	Moreover, α3'-GL content was 2 times higher than in colostrum and 10 times higher in transitional milk than in mature milk; in contrast, for β3'-GL, the values were 5 and 2 times higher, respectively.					
35863928	0	75	from	stages	141:146	arg1	comparison					47:56	Qualitative and quantitative mass spectrometry comparison	0:56	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.	0:147	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	0	76	theme	galactosyl	76:85	arg1	isomers					95:101	characteristic galactosyl lactose isomers	61:101	characteristic galactosyl lactose isomers from goat milk	61:116	Qualitative and quantitative mass spectrometry comparison of characteristic galactosyl lactose isomers from goat milk at different lactation stages.					
35863928	6	77	theme	quantitative	949:960	arg1	analysis					962:969	Relative quantitative analysis	940:969	Relative quantitative analysis	940:969	Relative quantitative analysis showed that the total content of the 5 galactosyl lactose isomers was highest in transitional goat milk.					
35863928	2	78	dep	separation	381:390	arg1	the					377:379	the	377:379	the	377:379	Although galactosyl lactose is abundant in goat milk, its complex structure has hindered the separation and analysis of its isomers.					
35863928	10	79	from	milk	1641:1644	arg1	α3'-GL					1596:1601	α3'-GL	1596:1601	α3'-GL	1596:1601	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	79	from	milk	1641:1644	arg1	abundant					1616:1623	abundant	1616:1623	abundant	1616:1623	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	7	80	theme	mature	1181:1186	arg1	milk					1188:1191	transitional and mature milk	1164:1191	transitional and mature milk	1164:1191	Specifically, β3'-GL was the main isomer in colostrum and α3'-GL was the main isomer in transitional and mature milk.					
35863928	10	81	theme	abundant	1549:1556	arg1	β3'-GL					1529:1534	β3'-GL	1529:1534	β3'-GL	1529:1534	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
35863928	10	81	theme	abundant	1549:1556	arg1	isomers					1558:1564	the most abundant isomers	1540:1564	the most abundant isomers	1540:1564	Absolute quantitative analysis revealed that β3'-GL was the most abundant isomers in colostrum (32.3 mg/L), and α3'-GL was the most abundant in transitional milk (88.1 mg/L) and mature milk (36.3 mg/L).					
36668845	3	0	theme	Cooked	450:455	arg1	meat					457:460	Cooked meat	450:460	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	9	1	theme	dry-fermented	1408:1420	arg1	products					1427:1434	dry-fermented meat products	1408:1434	dry-fermented meat products	1408:1434	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	3	2	theme	0.2	616:618	arg1	%					619:619	%	619:619	%	619:619	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	6	3	theme	growth	1041:1046	arg1	rate					1048:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	6	4	theme	mean	1029:1032	arg1	rate					1048:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	9	5	theme	novel	1437:1441	arg1	media					1452:1456	novel suitable media	1437:1456	novel suitable media such as CMA2-based media	1437:1481	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	9	5	theme	novel	1437:1441	arg1	media					1477:1481	CMA2-based media	1466:1481	CMA2-based media	1466:1481	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	7	6	theme	solid	1190:1194	arg1	SPE					1214:1216	SPE	1214:1216	SPE	1214:1216	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	7	6	theme	solid	1190:1194	arg1	extraction					1202:1211	solid phase extraction	1190:1211	solid phase extraction (SPE)	1190:1217	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	3	7	theme	novel	488:492	arg1	medium					513:518	a novel complex meat-based medium	486:518	a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	486:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	7	theme	novel	488:492	arg1	agar					462:465	Cooked meat agar	450:465	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	1	8	theme	similar	168:174	arg1	compositions					155:166	compositions	155:166	compositions similar to those of dry-fermented meat products	155:214	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	9	theme	yeast	621:625	arg1	extract					627:633	0.2% yeast extract	616:633	0.2% yeast extract	616:633	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	10	dep	variations	530:539	arg1	CMA2GYE					641:647	CMA2GYE	641:647	CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	641:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	10	dep	variations	530:539	arg1	variations					530:539	four variations	525:539	four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	525:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	10	dep	variations	530:539	arg1	CMA2YE					585:590	CMA2YE	585:590	CMA2YE (CMA2 supplemented with 0.2% yeast extract)	585:634	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	10	dep	variations	530:539	arg1	CMA2G					542:546	CMA2G	542:546	CMA2G (CMA2 supplemented with 1% glucose)	542:582	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	11	dep	CMA2G	542:546	arg1	CMA2					549:552	CMA2	549:552	CMA2 supplemented with 1% glucose	549:581	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	4	12	theme	A.	739:740	arg1	suspension					760:769	an A. parasiticus spore suspension	736:769	an A. parasiticus spore suspension (105 spores/mL)	736:785	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	4	12	theme	A.	739:740	arg1	spores/mL					776:784	105 spores/mL	772:784	105 spores/mL	772:784	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	8	13	theme	highest	1224:1230	arg1	concentration					1237:1249	The highest AFB1 concentration	1220:1249	The highest AFB1 concentration in meat-based media	1220:1269	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	8	14	dep	±	1331:1331	arg1	media					1344:1348	2367 ng/mL media	1333:1348	13,502 ± 2367 ng/mL media	1324:1348	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	3	15	theme	meat-based	502:511	arg1	medium					513:518	a novel complex meat-based medium	486:518	a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	486:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	15	theme	meat-based	502:511	arg1	agar					462:465	Cooked meat agar	450:465	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	4	16	theme	spore	754:758	arg1	suspension					760:769	an A. parasiticus spore suspension	736:769	an A. parasiticus spore suspension (105 spores/mL)	736:785	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	4	16	theme	spore	754:758	arg1	spores/mL					776:784	105 spores/mL	772:784	105 spores/mL	772:784	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	3	17	theme	1	673:673	arg1	%					674:674	%	674:674	%	674:674	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	10	18	theme	meat	1593:1596	arg1	products					1598:1605	dry-fermented meat products	1579:1605	dry-fermented meat products	1579:1605	This finding could represent a potential concern with regard to the production of dry-fermented meat products.					
36668845	1	19	theme	study	112:116	arg1	aim					93:95	The aim	89:95	The aim of the present study	89:116	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	20	theme	yeast	693:697	arg1	extract					699:705	0.2% yeast extract	688:705	0.2% yeast extract	688:705	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	2	21	theme	AFB1	444:447	arg1	AFB1					444:447	AFB1	444:447	AFB1	444:447	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	2	21	theme	AFB1	444:447	arg1	amount					434:439	a high amount	427:439	a high amount of AFB1	427:447	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	8	22	theme	meat-based	1254:1263	arg1	media					1265:1269	meat-based media	1254:1269	meat-based media	1254:1269	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	1	23	theme	kinetics	300:307	arg1	growth					258:263	the growth	254:263	the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production	254:341	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	24	theme	0.2	688:690	arg1	%					691:691	%	691:691	%	691:691	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	0	25	theme	Novel	65:69	arg1	Media					82:86	a Novel Meat-Based Media	63:86	a Novel Meat-Based Media	63:86	Production of Aflatoxin B1 by Aspergillus parasiticus Grown on a Novel Meat-Based Media.					
36668845	1	26	theme	aflatoxin	312:320	arg1	AFB1					326:329	AFB1	326:329	AFB1	326:329	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	1	26	theme	aflatoxin	312:320	arg1	B1					322:323	aflatoxin B1	312:323	aflatoxin B1 (AFB1) production	312:341	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	1	27	theme	meat-based	133:142	arg1	media					144:148	meat-based media	133:148	meat-based media with compositions similar to those of dry-fermented meat products	133:214	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	5	28	theme	cooked	960:965	arg1	meat					967:970	cooked meat	960:970	cooked meat agar	960:975	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	2	29	theme	previous	351:358	arg1	experiments					360:370	our previous experiments	347:370	our previous experiments	347:370	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	8	30	from	concentration	1237:1249	arg1	media					1265:1269	meat-based media	1254:1269	meat-based media	1254:1269	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	5	31	theme	growth	902:907	arg1	medium					909:914	the growth medium	898:914	the growth medium	898:914	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	2	32	theme	A.	398:399	arg1	ŽMJ7					413:416	the strain A. parasiticus ŽMJ7	387:416	the strain A. parasiticus ŽMJ7	387:416	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	7	33	theme	Reversed-phase	1085:1098	arg1	analysis					1111:1118	Reversed-phase UPLC-MS/MS analysis	1085:1118	Reversed-phase UPLC-MS/MS analysis	1085:1118	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	8	34	theme	incubation	1312:1321	arg1	days					1304:1307	15 days	1301:1307	15 days of incubation (13,502 ± 2367 ng/mL media)	1301:1349	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	0	35	theme	Aflatoxin	14:22	arg1	B1					24:25	Aflatoxin B1	14:25	Aflatoxin B1	14:25	Production of Aflatoxin B1 by Aspergillus parasiticus Grown on a Novel Meat-Based Media.					
36668845	5	36	theme	meat	967:970	arg1	CMA1					954:957	control medium CMA1	939:957	control medium CMA1 (cooked meat agar) as an already known meat-based medium	939:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	5	36	theme	meat	967:970	arg1	agar					972:975	cooked meat agar	960:975	cooked meat agar	960:975	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	7	37	from	concentration	1156:1168	arg1	combination					1173:1183	combination	1173:1183	combination with solid phase extraction (SPE)	1173:1217	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	5	38	theme	A.	833:834	arg1	phase					852:856	The A. parasiticus lag phase	829:856	The A. parasiticus lag phase	829:856	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	8	39	theme	2367	1333:1336	arg1	ng/mL					1338:1342	ng/mL	1338:1342	ng/mL	1338:1342	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	5	40	theme	medium	947:952	arg1	CMA1					954:957	control medium CMA1	939:957	control medium CMA1 (cooked meat agar) as an already known meat-based medium	939:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	5	40	theme	medium	947:952	arg1	agar					972:975	cooked meat agar	960:975	cooked meat agar	960:975	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	5	41	theme	lag	848:850	arg1	phase					852:856	The A. parasiticus lag phase	829:856	The A. parasiticus lag phase	829:856	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	5	42	theme	known	992:996	arg1	medium					1009:1014	an already known meat-based medium	981:1014	an already known meat-based medium	981:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	3	43	theme	%	573:573	arg1	glucose					575:581	1% glucose	572:581	1% glucose	572:581	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	44	theme	meat	457:460	arg1	medium					513:518	a novel complex meat-based medium	486:518	a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	486:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	44	theme	meat	457:460	arg1	CMA2					468:471	CMA2	468:471	CMA2	468:471	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	44	theme	meat	457:460	arg1	agar					462:465	Cooked meat agar	450:465	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	9	45	theme	AFB1	1389:1392	arg1	production					1394:1403	AFB1 production	1389:1403	AFB1 production in dry-fermented meat products	1389:1434	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	5	46	theme	control	939:945	arg1	CMA1					954:957	control medium CMA1	939:957	control medium CMA1 (cooked meat agar) as an already known meat-based medium	939:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	5	46	theme	control	939:945	arg1	agar					972:975	cooked meat agar	960:975	cooked meat agar	960:975	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	4	47	dep	A.	739:740	arg1	parasiticus					742:752	parasiticus	742:752	parasiticus	742:752	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	4	48	dep	15	820:821	arg1	to					817:818	to	817:818	to	817:818	Media were inoculated with an A. parasiticus spore suspension (105 spores/mL) and incubated at 25 °C for up to 15 days.					
36668845	9	49	theme	meat	1422:1425	arg1	products					1427:1434	dry-fermented meat products	1408:1434	dry-fermented meat products	1408:1434	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	3	50	theme	%	619:619	arg1	extract					627:633	0.2% yeast extract	616:633	0.2% yeast extract	616:633	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	6	51	theme	colony	1034:1039	arg1	rate					1048:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	6	52	theme	highest	1021:1027	arg1	rate					1048:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	9	53	theme	suitable	1443:1450	arg1	media					1452:1456	novel suitable media	1437:1456	novel suitable media such as CMA2-based media	1437:1481	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	9	53	theme	suitable	1443:1450	arg1	media					1477:1481	CMA2-based media	1466:1481	CMA2-based media	1466:1481	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	7	54	theme	phase	1196:1200	arg1	SPE					1214:1216	SPE	1214:1216	SPE	1214:1216	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	7	54	theme	phase	1196:1200	arg1	extraction					1202:1211	solid phase extraction	1190:1211	solid phase extraction (SPE)	1190:1217	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	5	55	dep	A.	833:834	arg1	parasiticus					836:846	parasiticus	836:846	parasiticus	836:846	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	10	56	theme	potential	1528:1536	arg1	concern					1538:1544	a potential concern	1526:1544	a potential concern with regard to the production of dry-fermented meat products	1526:1605	This finding could represent a potential concern with regard to the production of dry-fermented meat products.					
36668845	3	57	used	used	478:481	arg2	agar					462:465	Cooked meat agar	450:465	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	57	used	used	478:481	arg2	CMA2					468:471	CMA2	468:471	CMA2	468:471	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	57	used	used	478:481	arg2	medium					513:518	a novel complex meat-based medium	486:518	a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	486:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	9	58	theme	CMA2-based	1466:1475	arg1	media					1477:1481	CMA2-based media	1466:1481	CMA2-based media	1466:1481	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	8	59	theme	AFB1	1232:1235	arg1	concentration					1237:1249	The highest AFB1 concentration	1220:1249	The highest AFB1 concentration in meat-based media	1220:1269	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	3	60	theme	complex	494:500	arg1	medium					513:518	a novel complex meat-based medium	486:518	a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	486:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	60	theme	complex	494:500	arg1	agar					462:465	Cooked meat agar	450:465	Cooked meat agar (CMA2)	450:472	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	9	61	from	production	1394:1403	arg1	products					1427:1434	dry-fermented meat products	1408:1434	dry-fermented meat products	1408:1434	The results showed that for studying AFB1 production in dry-fermented meat products, novel suitable media such as CMA2-based media are required.					
36668845	7	62	theme	AFB1	1151:1154	arg1	concentration					1156:1168	the AFB1 concentration	1147:1168	the AFB1 concentration in combination with solid phase extraction (SPE)	1147:1217	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	10	63	theme	products	1598:1605	arg1	production					1565:1574	the production	1561:1574	the production of dry-fermented meat products	1561:1605	This finding could represent a potential concern with regard to the production of dry-fermented meat products.					
36668845	1	64	theme	present	104:110	arg1	study					112:116	the present study	100:116	the present study	100:116	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	65	theme	%	674:674	arg1	glucose					676:682	1% glucose	673:682	1% glucose	673:682	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	8	66	dep	incubation	1312:1321	arg1	±					1331:1331	13,502 ±	1324:1331	13,502 ± 2367 ng/mL media	1324:1348	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	10	67	theme	dry-fermented	1579:1591	arg1	products					1598:1605	dry-fermented meat products	1579:1605	dry-fermented meat products	1579:1605	This finding could represent a potential concern with regard to the production of dry-fermented meat products.					
36668845	1	68	theme	meat	202:205	arg1	products					207:214	dry-fermented meat products	188:214	dry-fermented meat products	188:214	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	0	69	theme	Meat-Based	71:80	arg1	Media					82:86	a Novel Meat-Based Media	63:86	a Novel Meat-Based Media	63:86	Production of Aflatoxin B1 by Aspergillus parasiticus Grown on a Novel Meat-Based Media.					
36668845	2	70	theme	high	429:432	arg1	AFB1					444:447	AFB1	444:447	AFB1	444:447	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	2	70	theme	high	429:432	arg1	amount					434:439	a high amount	427:439	a high amount of AFB1	427:447	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	3	71	theme	%	691:691	arg1	extract					699:705	0.2% yeast extract	688:705	0.2% yeast extract	688:705	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	1	72	theme	B1	322:323	arg1	production					332:341	aflatoxin B1 (AFB1) production	312:341	aflatoxin B1 (AFB1) production	312:341	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	73	with	medium	513:518	arg1	CMA2GYE					641:647	CMA2GYE	641:647	CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	641:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	73	with	medium	513:518	arg1	variations					530:539	four variations	525:539	four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract)	525:706	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	73	with	medium	513:518	arg1	CMA2YE					585:590	CMA2YE	585:590	CMA2YE (CMA2 supplemented with 0.2% yeast extract)	585:634	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	73	with	medium	513:518	arg1	CMA2G					542:546	CMA2G	542:546	CMA2G (CMA2 supplemented with 1% glucose)	542:582	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	3	74	dep	CMA2GYE	641:647	arg1	CMA2					650:653	CMA2	650:653	CMA2 supplemented with 1% glucose and 0.2% yeast extract	650:705	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	8	75	located	detected	1275:1282	arg1	CMA2GYE					1287:1293	CMA2GYE	1287:1293	CMA2GYE	1287:1293	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	8	75	located	detected	1275:1282	arg2	concentration					1237:1249	The highest AFB1 concentration	1220:1249	The highest AFB1 concentration in meat-based media	1220:1269	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	7	76	theme	UPLC-MS/MS	1100:1109	arg1	analysis					1111:1118	Reversed-phase UPLC-MS/MS analysis	1085:1118	Reversed-phase UPLC-MS/MS analysis	1085:1118	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	7	77	with	combination	1173:1183	arg1	SPE					1214:1216	SPE	1214:1216	SPE	1214:1216	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	7	77	with	combination	1173:1183	arg1	extraction					1202:1211	solid phase extraction	1190:1211	solid phase extraction (SPE)	1190:1217	Reversed-phase UPLC-MS/MS analysis was performed to determine the AFB1 concentration in combination with solid phase extraction (SPE).					
36668845	1	78	theme	production	332:341	arg1	kinetics					300:307	the kinetics	296:307	the kinetics of aflatoxin B1 (AFB1) production	296:341	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	2	79	dep	A.	398:399	arg1	parasiticus					401:411	parasiticus	401:411	parasiticus	401:411	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	2	80	theme	strain	391:396	arg1	ŽMJ7					413:416	the strain A. parasiticus ŽMJ7	387:416	the strain A. parasiticus ŽMJ7	387:416	In our previous experiments, we found that the strain A. parasiticus ŽMJ7 produced a high amount of AFB1.					
36668845	0	81	theme	B1	24:25	arg1	Production					0:9	Production	0:9	Production of Aflatoxin B1 by Aspergillus parasiticus	0:52	Production of Aflatoxin B1 by Aspergillus parasiticus Grown on a Novel Meat-Based Media.					
36668845	3	82	dep	CMA2YE	585:590	arg1	CMA2					593:596	CMA2	593:596	CMA2 supplemented with 0.2% yeast extract	593:633	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	6	83	located	observed	1057:1064	arg2	rate					1048:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate	1017:1051	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	6	83	located	observed	1057:1064	arg1	CMA2G					1078:1082	CMA2G	1078:1082	CMA2G	1078:1082	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	6	83	located	observed	1057:1064	arg1	CMA2					1069:1072	CMA2	1069:1072	CMA2	1069:1072	The highest mean colony growth rate was observed on CMA2 and CMA2G.					
36668845	8	84	theme	ng/mL	1338:1342	arg1	media					1344:1348	2367 ng/mL media	1333:1348	13,502 ± 2367 ng/mL media	1324:1348	The highest AFB1 concentration in meat-based media was detected in CMA2GYE after 15 days of incubation (13,502 ± 2367 ng/mL media).					
36668845	1	85	theme	parasiticus	280:290	arg1	growth					258:263	the growth	254:263	the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production	254:341	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	5	86	theme	CMA1	954:957	arg1	exception					926:934	the exception	922:934	the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium	922:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	1	87	with	media	144:148	arg1	compositions					155:166	compositions	155:166	compositions similar to those of dry-fermented meat products	155:214	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36668845	3	88	theme	1	572:572	arg1	%					573:573	%	573:573	%	573:573	Cooked meat agar (CMA2) was used as a novel complex meat-based medium with four variations: CMA2G (CMA2 supplemented with 1% glucose), CMA2YE (CMA2 supplemented with 0.2% yeast extract), and CMA2GYE (CMA2 supplemented with 1% glucose and 0.2% yeast extract).					
36668845	5	89	theme	meat-based	998:1007	arg1	medium					1009:1014	an already known meat-based medium	981:1014	an already known meat-based medium	981:1014	The A. parasiticus lag phase lasted less than 1 day, irrespective of the growth medium, with the exception of control medium CMA1 (cooked meat agar) as an already known meat-based medium.					
36668845	1	90	theme	dry-fermented	188:200	arg1	products					207:214	dry-fermented meat products	188:214	dry-fermented meat products	188:214	The aim of the present study was to develop meat-based media with compositions similar to those of dry-fermented meat products and to evaluate their use in studying the growth of Aspergillus parasiticus and the kinetics of aflatoxin B1 (AFB1) production.					
36925480	7	0	theme	located	1294:1300	arg1	C-terminally					1281:1292	C-terminally	1281:1292	C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference	1281:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	9	1	theme	activity	1630:1637	arg1	effect					1648:1653	the activity boosting effect	1626:1653	the activity boosting effect of the added reducing agents L-cysteine and DTT	1626:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	2	2	theme	Lactobacillaceae	298:313	arg1	family					315:320	the aciduric Lactobacillaceae family	285:320	the aciduric Lactobacillaceae family	285:320	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	12	3	theme	biofilm	2073:2079	arg1	dynamics					2081:2088	complex biofilm dynamics	2065:2088	complex biofilm dynamics	2065:2088	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	3	4	theme	high	608:611	arg1	similarity					630:639	a high protein backbone similarity	606:639	a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition	606:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	5	5	theme	hydrolytic	921:930	arg1	proteins					941:948	proteins	941:948	proteins with a high O-glycan occurrence	941:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	5	5	theme	hydrolytic	921:930	arg1	sites					932:936	multiple hydrolytic sites	912:936	multiple hydrolytic sites of proteins with a high O-glycan occurrence	912:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	12	6	theme	mucin	2043:2047	arg1	degradation					2049:2059	mucin degradation	2043:2059	mucin degradation	2043:2059	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	3	7	dep	MdpL	544:547	arg1	protease					566:573	Mucin degrading protease	550:573	Mucin degrading protease from Limosilactobacillus	550:598	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	1	8	theme	predominant	120:130	arg1	glycoprotein					132:143	the predominant glycoprotein	116:143	the predominant glycoprotein in saliva	116:153	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	8	theme	predominant	120:130	arg1	MUC5B					107:111	MUC5B	107:111	MUC5B	107:111	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	11	9	theme	mucin	1872:1876	arg1	protease					1888:1895	a highly conserved mucin degrading protease	1853:1895	a highly conserved mucin degrading protease from L. fermentum	1853:1913	Here we have characterized a highly conserved mucin degrading protease from L. fermentum.					
36925480	1	10	gly	glycoprotein	132:143	arg1	glycoprotein					132:143	the predominant glycoprotein	116:143	the predominant glycoprotein in saliva	116:153	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	10	gly	glycoprotein	132:143	arg1	MUC5B					107:111	MUC5B	107:111	MUC5B	107:111	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	5	11	theme	substrate	882:890	arg1	preference					892:901	the substrate preference	878:901	the substrate preference	878:901	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	8	12	theme	complex	1507:1513	arg1	system					1515:1520	a complex system	1505:1520	a complex system that establishes a reducing environment	1505:1560	To secure proper enzyme folding and optimal conditions for activity, L. fermentum incorporates a complex system that establishes a reducing environment.					
36925480	4	13	theme	bacterial	748:756	arg1	surface					763:769	the bacterial cell surface	744:769	the bacterial cell surface	744:769	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	3	14	theme	backbone	621:628	arg1	similarity					630:639	a high protein backbone similarity	606:639	a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition	606:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	1	15	from	maintenance	200:210	arg1	cavity					259:264	the oral cavity	250:264	the oral cavity	250:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	15	from	maintenance	200:210	arg1	instrumental					162:173	instrumental	162:173	instrumental	162:173	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	5	16	theme	high	957:960	arg1	occurrence					971:980	a high O-glycan occurrence	955:980	a high O-glycan occurrence	955:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	4	17	theme	close	775:779	arg1	proximity					781:789	close proximity	775:789	close proximity	775:789	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	0	18	from	fermentum	96:104	arg1	Characterization					0:15	Characterization	0:15	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.	0:105	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	0	18	from	fermentum	96:104	arg1	protease					55:62	a highly conserved MUC5B-degrading protease	20:62	a highly conserved MUC5B-degrading protease	20:62	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	0	18	from	fermentum	96:104	arg1	MdpL					65:68	MdpL	65:68	MdpL	65:68	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	7	19	theme	sequence	1389:1396	arg1	preference					1398:1407	a limited sequence preference	1379:1407	a limited sequence preference	1379:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	10	20	theme	neutral	1741:1747	arg1	pH					1749:1750	neutral pH 5.5-7.0	1741:1758	neutral pH 5.5-7.0	1741:1758	High activity was retained in low to neutral pH 5.5-7.0, but the enzyme was completely inhibited in the presence of Zn2+.					
36925480	9	21	theme	overall	1581:1587	arg1	conditions					1598:1607	overall reducing conditions	1581:1607	overall reducing conditions	1581:1607	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	5	22	with	proteins	941:948	arg1	occurrence					971:980	a high O-glycan occurrence	955:980	a high O-glycan occurrence	955:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	12	23	theme	discovered	1954:1963	arg1	O-glycanase					1965:1975	the recently discovered O-glycanase	1941:1975	the recently discovered O-glycanase	1941:1975	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	9	24	theme	conditions	1598:1607	arg1	importance					1567:1576	The importance	1563:1576	The importance of overall reducing conditions	1563:1607	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	2	25	from	role	331:334	arg1	biofilms					339:346	biofilms	339:346	biofilms	339:346	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	0	26	from	Characterization	0:15	arg1	fermentum					96:104	Limosilactobacillus fermentum	76:104	Limosilactobacillus fermentum	76:104	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	3	27	from	Limosilactobacillus	580:598	arg1	protease					566:573	Mucin degrading protease	550:573	Mucin degrading protease from Limosilactobacillus	550:598	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	1	28	from	establishment	182:194	arg1	cavity					259:264	the oral cavity	250:264	the oral cavity	250:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	28	from	establishment	182:194	arg1	instrumental					162:173	instrumental	162:173	instrumental	162:173	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	2	29	theme	systems	416:422	arg1	genera					390:395	different genera	380:395	different genera of the proteolytic systems involved in the nutritional utilization of mucins	380:472	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	1	30	from	glycoprotein	132:143	arg1	saliva					148:153	saliva	148:153	saliva	148:153	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	7	31	theme	limited	1381:1387	arg1	preference					1398:1407	a limited sequence preference	1379:1407	a limited sequence preference	1379:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	9	32	theme	reducing	1589:1596	arg1	conditions					1598:1607	overall reducing conditions	1581:1607	overall reducing conditions	1581:1607	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	8	33	theme	proper	1420:1425	arg1	folding					1434:1440	proper enzyme folding	1420:1440	proper enzyme folding	1420:1440	To secure proper enzyme folding and optimal conditions for activity, L. fermentum incorporates a complex system that establishes a reducing environment.					
36925480	9	34	theme	boosting	1639:1646	arg1	effect					1648:1653	the activity boosting effect	1626:1653	the activity boosting effect of the added reducing agents L-cysteine and DTT	1626:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	11	35	from	fermentum	1905:1913	arg1	protease					1888:1895	a highly conserved mucin degrading protease	1853:1895	a highly conserved mucin degrading protease from L. fermentum	1853:1913	Here we have characterized a highly conserved mucin degrading protease from L. fermentum.					
36925480	4	36	theme	molecular	842:850	arg1	fragments					859:867	low molecular weight fragments	838:867	low molecular weight fragments	838:867	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	2	37	theme	nutritional	440:450	arg1	utilization					452:462	the nutritional utilization	436:462	the nutritional utilization of mucins	436:472	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	3	38	theme	degrading	556:564	arg1	protease					566:573	Mucin degrading protease	550:573	Mucin degrading protease from Limosilactobacillus	550:598	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	6	39	theme	immunoglobulins	1081:1095	arg1	proteolysis					1066:1076	proteolysis	1066:1076	proteolysis of immunoglobulins	1066:1095	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	8	40	theme	optimal	1446:1452	arg1	conditions					1454:1463	optimal conditions	1446:1463	optimal conditions for activity	1446:1476	To secure proper enzyme folding and optimal conditions for activity, L. fermentum incorporates a complex system that establishes a reducing environment.					
36925480	6	41	from	MUC5B	1190:1194	arg1	terms					1199:1203	terms	1199:1203	terms of glycosylation and structure	1199:1234	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	0	42	theme	conserved	29:37	arg1	MdpL					65:68	MdpL	65:68	MdpL	65:68	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	0	42	theme	conserved	29:37	arg1	protease					55:62	a highly conserved MUC5B-degrading protease	20:62	a highly conserved MUC5B-degrading protease	20:62	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	9	43	theme	added	1662:1666	arg1	agents					1677:1682	the added reducing agents	1658:1682	the added reducing agents L-cysteine and DTT	1658:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	43	theme	added	1662:1666	arg1	DTT					1699:1701	DTT	1699:1701	DTT	1699:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	43	theme	added	1662:1666	arg1	L-cysteine					1684:1693	L-cysteine	1684:1693	L-cysteine	1684:1693	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	0	44	theme	protease	55:62	arg1	Characterization					0:15	Characterization	0:15	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.	0:105	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	9	45	theme	agents	1677:1682	arg1	effect					1648:1653	the activity boosting effect	1626:1653	the activity boosting effect of the added reducing agents L-cysteine and DTT	1626:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	1	46	theme	biofilms	238:245	arg1	establishment					182:194	establishment	182:194	establishment	182:194	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	46	theme	biofilms	238:245	arg1	maintenance					200:210	maintenance	200:210	maintenance	200:210	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	7	47	theme	larger	1335:1340	arg1	residues					1314:1321	hydrophobic residues	1302:1321	hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference	1302:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	12	48	theme	dynamics	2081:2088	arg1	understanding					2026:2038	our understanding	2022:2038	our understanding of mucin degradation and complex biofilm dynamics	2022:2088	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	7	49	theme	hydrophobic	1302:1312	arg1	residues					1314:1321	hydrophobic residues	1302:1321	hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference	1302:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	2	50	theme	family	315:320	arg1	Investigations					267:280	Investigations	267:280	Investigations of the aciduric Lactobacillaceae family	267:320	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	2	50	theme	family	315:320	arg1	role					331:334	its role	327:334	its role in biofilms	327:346	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	12	51	theme	degradation	2049:2059	arg1	understanding					2026:2038	our understanding	2022:2038	our understanding of mucin degradation and complex biofilm dynamics	2022:2088	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	7	52	from	residues	1314:1321	arg1	peptides					1326:1333	peptides	1326:1333	peptides	1326:1333	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	6	53	theme	glycosylation	1208:1220	arg1	terms					1199:1203	terms	1199:1203	terms of glycosylation and structure	1199:1234	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	3	54	with	protease	499:506	arg1	similarity					630:639	a high protein backbone similarity	606:639	a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition	606:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	2	55	theme	aciduric	289:296	arg1	family					315:320	the aciduric Lactobacillaceae family	285:320	the aciduric Lactobacillaceae family	285:320	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	12	56	theme	complex	2065:2071	arg1	dynamics					2081:2088	complex biofilm dynamics	2065:2088	complex biofilm dynamics	2065:2088	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	9	57	dep	agents	1677:1682	arg1	agents					1677:1682	the added reducing agents	1658:1682	the added reducing agents L-cysteine and DTT	1658:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	57	dep	agents	1677:1682	arg1	DTT					1699:1701	DTT	1699:1701	DTT	1699:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	57	dep	agents	1677:1682	arg1	L-cysteine					1684:1693	L-cysteine	1684:1693	L-cysteine	1684:1693	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	5	58	theme	multiple	912:919	arg1	proteins					941:948	proteins	941:948	proteins with a high O-glycan occurrence	941:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	5	58	theme	multiple	912:919	arg1	sites					932:936	multiple hydrolytic sites	912:936	multiple hydrolytic sites of proteins with a high O-glycan occurrence	912:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	3	59	from	fermentum	533:541	arg1	protease					499:506	a protease	497:506	a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition	497:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	10	60	theme	Zn2+	1820:1823	arg1	presence					1808:1815	the presence	1804:1815	the presence of Zn2+	1804:1823	High activity was retained in low to neutral pH 5.5-7.0, but the enzyme was completely inhibited in the presence of Zn2+.					
36925480	6	61	theme	similar	1179:1185	arg1	glycoproteins					1165:1177	glycoproteins	1165:1177	glycoproteins similar to MUC5B in terms of glycosylation and structure	1165:1234	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	1	62	from	cavity	259:264	arg1	establishment					182:194	establishment	182:194	establishment	182:194	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	62	from	cavity	259:264	arg1	maintenance					200:210	maintenance	200:210	maintenance	200:210	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	63	theme	multi-species	215:227	arg1	biofilms					238:245	multi-species eubiotic biofilms	215:245	multi-species eubiotic biofilms in the oral cavity	215:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	12	64	theme	enzyme	1997:2002	arg1	groups					2004:2009	O-glycoprotease enzyme groups	1981:2009	O-glycoprotease enzyme groups	1981:2009	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	11	65	theme	degrading	1878:1886	arg1	protease					1888:1895	a highly conserved mucin degrading protease	1853:1895	a highly conserved mucin degrading protease from L. fermentum	1853:1913	Here we have characterized a highly conserved mucin degrading protease from L. fermentum.					
36925480	3	66	theme	protein	613:619	arg1	similarity					630:639	a high protein backbone similarity	606:639	a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition	606:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	11	67	theme	conserved	1862:1870	arg1	protease					1888:1895	a highly conserved mucin degrading protease	1853:1895	a highly conserved mucin degrading protease from L. fermentum	1853:1913	Here we have characterized a highly conserved mucin degrading protease from L. fermentum.					
36925480	1	68	from	biofilms	238:245	arg1	cavity					259:264	the oral cavity	250:264	the oral cavity	250:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	5	69	theme	O-glycan	962:969	arg1	occurrence					971:980	a high O-glycan occurrence	955:980	a high O-glycan occurrence	955:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	8	70	theme	reducing	1541:1548	arg1	environment					1550:1560	a reducing environment	1539:1560	a reducing environment	1539:1560	To secure proper enzyme folding and optimal conditions for activity, L. fermentum incorporates a complex system that establishes a reducing environment.					
36925480	4	71	theme	cell	758:761	arg1	surface					763:769	the bacterial cell surface	744:769	the bacterial cell surface	744:769	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	6	72	theme	structure	1226:1234	arg1	terms					1199:1203	terms	1199:1203	terms of glycosylation and structure	1199:1234	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	5	73	theme	proteins	941:948	arg1	proteins					941:948	proteins	941:948	proteins with a high O-glycan occurrence	941:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	5	73	theme	proteins	941:948	arg1	sites					932:936	multiple hydrolytic sites	912:936	multiple hydrolytic sites of proteins with a high O-glycan occurrence	912:980	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	12	74	theme	O-glycoprotease	1981:1995	arg1	groups					2004:2009	O-glycoprotease enzyme groups	1981:2009	O-glycoprotease enzyme groups	1981:2009	MdpL, that together with the recently discovered O-glycanase and O-glycoprotease enzyme groups, increases our understanding of mucin degradation and complex biofilm dynamics.					
36925480	1	75	from	instrumental	162:173	arg1	establishment					182:194	establishment	182:194	establishment	182:194	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	1	75	from	instrumental	162:173	arg1	maintenance					200:210	maintenance	200:210	maintenance	200:210	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	3	76	with	similarity	630:639	arg1	commensals					646:655	commensals	646:655	commensals that exploit mucins for attachment and nutrition	646:704	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	6	77	theme	protease	1121:1128	arg1	activity					1130:1137	general protease activity	1113:1137	general protease activity	1113:1137	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	6	78	gly	glycoproteins	1165:1177	arg1	glycoproteins					1165:1177	glycoproteins	1165:1177	glycoproteins similar to MUC5B in terms of glycosylation and structure	1165:1234	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	2	79	theme	proteolytic	404:414	arg1	systems					416:422	the proteolytic systems	400:422	the proteolytic systems involved in the nutritional utilization of mucins	400:472	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	7	80	dep	located	1294:1300	arg1	residues					1314:1321	hydrophobic residues	1302:1321	hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference	1302:1407	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	2	81	theme	mucins	467:472	arg1	utilization					452:462	the nutritional utilization	436:462	the nutritional utilization of mucins	436:472	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	10	82	theme	High	1704:1707	arg1	activity					1709:1716	High activity	1704:1716	High activity	1704:1716	High activity was retained in low to neutral pH 5.5-7.0, but the enzyme was completely inhibited in the presence of Zn2+.					
36925480	8	83	theme	enzyme	1427:1432	arg1	folding					1434:1440	proper enzyme folding	1420:1440	proper enzyme folding	1420:1440	To secure proper enzyme folding and optimal conditions for activity, L. fermentum incorporates a complex system that establishes a reducing environment.					
36925480	0	84	theme	MUC5B-degrading	39:53	arg1	MdpL					65:68	MdpL	65:68	MdpL	65:68	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	0	84	theme	MUC5B-degrading	39:53	arg1	protease					55:62	a highly conserved MUC5B-degrading protease	20:62	a highly conserved MUC5B-degrading protease	20:62	Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum.					
36925480	2	85	from	Investigations	267:280	arg1	biofilms					339:346	biofilms	339:346	biofilms	339:346	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	7	86	theme	amino	1350:1354	arg1	acids					1356:1360	20 amino acids	1347:1360	20 amino acids	1347:1360	MdpL preferentially hydrolyzed C-terminally located hydrophobic residues in peptides larger than 20 amino acids, which hinted at a limited sequence preference.					
36925480	4	87	theme	low	838:840	arg1	fragments					859:867	low molecular weight fragments	838:867	low molecular weight fragments	838:867	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	9	88	theme	reducing	1668:1675	arg1	agents					1677:1682	the added reducing agents	1658:1682	the added reducing agents L-cysteine and DTT	1658:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	88	theme	reducing	1668:1675	arg1	DTT					1699:1701	DTT	1699:1701	DTT	1699:1701	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	9	88	theme	reducing	1668:1675	arg1	L-cysteine					1684:1693	L-cysteine	1684:1693	L-cysteine	1684:1693	The importance of overall reducing conditions was confirmed by the activity boosting effect of the added reducing agents L-cysteine and DTT.					
36925480	4	89	theme	weight	852:857	arg1	fragments					859:867	low molecular weight fragments	838:867	low molecular weight fragments	838:867	MdpL was shown to be associated with the bacterial cell surface, in close proximity to MUC5B, which was sequentially degraded into low molecular weight fragments.					
36925480	2	90	theme	different	380:388	arg1	genera					390:395	different genera	380:395	different genera of the proteolytic systems involved in the nutritional utilization of mucins	380:472	Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins.					
36925480	1	91	theme	eubiotic	229:236	arg1	biofilms					238:245	multi-species eubiotic biofilms	215:245	multi-species eubiotic biofilms in the oral cavity	215:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
36925480	5	92	theme	O-glycans	1040:1048	arg1	presence					1028:1035	the presence	1024:1035	the presence of O-glycans	1024:1048	Mapping the substrate preference revealed multiple hydrolytic sites of proteins with a high O-glycan occurrence, although hydrolysis was not dependent on the presence of O-glycans.					
36925480	6	93	theme	general	1113:1119	arg1	activity					1130:1137	general protease activity	1113:1137	general protease activity	1113:1137	However, since proteolysis of immunoglobulins was absent, and general protease activity was low, a preference for glycoproteins similar to MUC5B in terms of glycosylation and structure is suggested.					
36925480	3	94	theme	Mucin	550:554	arg1	protease					566:573	Mucin degrading protease	550:573	Mucin degrading protease from Limosilactobacillus	550:598	We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading protease from Limosilactobacillus) with a high protein backbone similarity with commensals that exploit mucins for attachment and nutrition.					
36925480	1	95	theme	oral	254:257	arg1	cavity					259:264	the oral cavity	250:264	the oral cavity	250:264	MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity.					
35408623	0	0	theme	Sugar	83:87	arg1	Types					74:78	Different Types	64:78	Different Types of Sugar	64:87	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	3	1	theme	NMR	289:291	arg1	experiments					317:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	5	2	theme	water	732:736	arg1	molecules					738:746	water molecules	732:746	water molecules	732:746	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	6	3	theme	sample	845:850	arg1	composition					852:862	the sample composition	841:862	the sample composition (the type of sugar and/or the presence of SPI)	841:909	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	1	4	theme	sugar	165:169	arg1	types					156:160	different types	146:160	different types of sugar	146:169	Starch-based confectionery products were prepared using different types of sugar.					
35408623	3	5	theme	spin-lattice	293:304	arg1	experiments					317:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	0	6	from	Dynamics	6:13	arg1	Products					45:52	Starch Based Confectionery Products	18:52	Starch Based Confectionery Products	18:52	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	3	7	theme	different	460:468	arg1	types					476:480	different sugar types	460:480	different sugar types	460:480	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	8	8	theme	complementary	1095:1107	arg1	measurements					1109:1120	the complementary measurements	1091:1120	the complementary measurements	1091:1120	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	8	theme	complementary	1095:1107	arg1	properties					1132:1141	physical properties	1123:1141	physical properties of the products, such as the moisture content, water activity and texture,	1123:1216	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	9	theme	thermogravimetric	1270:1286	arg1	analysis					1288:1295	thermogravimetric analysis	1270:1295	thermogravimetric analysis	1270:1295	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	2	10	dep	using	187:191	arg1	addition					175:182	addition	175:182	addition	175:182	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	4	11	theme	water	651:655	arg1	molecules					657:665	water molecules	651:665	water molecules characterized by different mobility	651:701	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	6	12	from	influence	828:836	arg1	mobility					924:931	the water mobility	914:931	the water mobility	914:931	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	8	13	theme	water	1190:1194	arg1	activity					1196:1203	water activity	1190:1203	water activity	1190:1203	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	14	theme	moisture	1172:1179	arg1	content					1181:1187	the moisture content	1168:1187	the moisture content	1168:1187	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	5	15	theme	translation	708:718	arg1	dynamics					720:727	The translation dynamics	704:727	The translation dynamics of water molecules	704:746	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	6	16	theme	composition	852:862	arg1	influence					828:836	The influence	824:836	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility	824:931	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	0	17	theme	Confectionery	31:43	arg1	Products					45:52	Starch Based Confectionery Products	18:52	Starch Based Confectionery Products	18:52	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	3	18	theme	SPI	486:488	arg1	influence					447:455	the influence	443:455	the influence of different sugar types and SPI on the dynamics of water in composite gel systems	443:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	3	19	theme	products	366:373	arg1	collection					352:361	the collection	348:361	the collection of products	348:373	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	5	20	theme	molecules	738:746	arg1	dynamics					720:727	The translation dynamics	704:727	The translation dynamics of water molecules	704:746	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	3	21	theme	water	509:513	arg1	dynamics					497:504	the dynamics	493:504	the dynamics of water in composite gel systems	493:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	0	22	theme	Water	0:4	arg1	Dynamics					6:13	Water Dynamics	0:13	Water Dynamics in Starch Based Confectionery Products	0:52	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	6	23	theme	water	918:922	arg1	mobility					924:931	the water mobility	914:931	the water mobility	914:931	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	7	24	theme	water	1029:1033	arg1	dynamics					1035:1042	water dynamics	1029:1042	water dynamics for samples including sucrose	1029:1072	The results indicate that the addition of soy protein does not affect water dynamics for samples including sucrose.					
35408623	1	25	theme	Starch-based	90:101	arg1	products					117:124	Starch-based confectionery products	90:124	Starch-based confectionery products	90:124	Starch-based confectionery products were prepared using different types of sugar.					
35408623	0	26	theme	Starch	18:23	arg1	Products					45:52	Starch Based Confectionery Products	18:52	Starch Based Confectionery Products	18:52	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	3	27	from	influence	447:455	arg1	dynamics					497:504	the dynamics	493:504	the dynamics of water in composite gel systems	493:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	1	28	theme	confectionery	103:115	arg1	products					117:124	Starch-based confectionery products	90:124	Starch-based confectionery products	90:124	Starch-based confectionery products were prepared using different types of sugar.					
35408623	5	29	theme	dedicated	796:804	arg1	model					817:821	a dedicated relaxation model	794:821	a dedicated relaxation model	794:821	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	8	30	theme	X-ray	1248:1252	arg1	diffraction					1254:1264	X-ray diffraction	1248:1264	X-ray diffraction	1248:1264	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	6	31	theme	sugar	877:881	arg1	type					869:872	the type	865:872	the type of sugar	865:881	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	5	32	theme	relaxation	806:815	arg1	model					817:821	a dedicated relaxation model	794:821	a dedicated relaxation model	794:821	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	3	33	theme	frequency	386:394	arg1	range					396:400	a broad frequency range	378:400	a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems	378:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	7	34	theme	soy	1001:1003	arg1	protein					1005:1011	soy protein	1001:1011	soy protein	1001:1011	The results indicate that the addition of soy protein does not affect water dynamics for samples including sucrose.					
35408623	5	35	theme	model	817:821	arg1	terms					785:789	terms	785:789	terms of a dedicated relaxation model	785:821	The translation dynamics of water molecules has been quantitatively described in terms of a dedicated relaxation model.					
35408623	2	36	theme	soy	235:237	arg1	isolate					247:253	soy protein isolate	235:253	soy protein isolate (SPI)	235:259	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	2	36	theme	soy	235:237	arg1	SPI					256:258	SPI	256:258	SPI	256:258	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	4	37	theme	relaxation	587:596	arg1	contributions					598:610	relaxation contributions	587:610	relaxation contributions associated with two different pools of water molecules characterized by different mobility	587:701	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	0	38	theme	Based	25:29	arg1	Products					45:52	Starch Based Confectionery Products	18:52	Starch Based Confectionery Products	18:52	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	6	39	theme	SPI	906:908	arg1	presence					894:901	the presence	890:901	the presence of SPI	890:908	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	6	40	dep	composition	852:862	arg1	presence					894:901	the presence	890:901	the presence of SPI	890:908	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	6	40	dep	composition	852:862	arg1	type					869:872	the type	865:872	the type of sugar	865:881	The influence of the sample composition (the type of sugar and/or the presence of SPI) on the water mobility was thoroughly discussed.					
35408623	8	41	theme	products	1150:1157	arg1	measurements					1109:1120	the complementary measurements	1091:1120	the complementary measurements	1091:1120	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	41	theme	products	1150:1157	arg1	properties					1132:1141	physical properties	1123:1141	physical properties of the products, such as the moisture content, water activity and texture,	1123:1216	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	3	42	theme	composite	518:526	arg1	systems					532:538	composite gel systems	518:538	composite gel systems	518:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	7	43	theme	protein	1005:1011	arg1	addition					989:996	the addition	985:996	the addition of soy protein	985:1011	The results indicate that the addition of soy protein does not affect water dynamics for samples including sucrose.					
35408623	3	44	theme	broad	380:384	arg1	range					396:400	a broad frequency range	378:400	a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems	378:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	3	45	theme	1H	286:287	arg1	experiments					317:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	3	46	theme	gel	528:530	arg1	systems					532:538	composite gel systems	518:538	composite gel systems	518:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	4	47	theme	molecules	657:665	arg1	pools					642:646	two different pools	628:646	two different pools of water molecules characterized by different mobility	628:701	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	3	48	from	dynamics	497:504	arg1	systems					532:538	composite gel systems	518:538	composite gel systems	518:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	4	49	theme	different	632:640	arg1	pools					642:646	two different pools	628:646	two different pools of water molecules characterized by different mobility	628:701	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	4	50	theme	different	684:692	arg1	mobility					694:701	different mobility	684:701	different mobility	684:701	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	4	51	theme	relaxation	545:554	arg1	data					556:559	The relaxation data	541:559	The relaxation data	541:559	The relaxation data have been decomposed into relaxation contributions associated with two different pools of water molecules characterized by different mobility.					
35408623	8	52	theme	analysis	1288:1295	arg1	terms					1239:1243	terms	1239:1243	terms of X-ray diffraction and thermogravimetric analysis	1239:1295	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	53	theme	physical	1123:1130	arg1	measurements					1109:1120	the complementary measurements	1091:1120	the complementary measurements	1091:1120	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	8	53	theme	physical	1123:1130	arg1	properties					1132:1141	physical properties	1123:1141	physical properties of the products, such as the moisture content, water activity and texture,	1123:1216	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	1	54	theme	different	146:154	arg1	types					156:160	different types	146:160	different types of sugar	146:169	Starch-based confectionery products were prepared using different types of sugar.					
35408623	8	55	theme	diffraction	1254:1264	arg1	terms					1239:1243	terms	1239:1243	terms of X-ray diffraction and thermogravimetric analysis	1239:1295	In addition, as the complementary measurements, physical properties of the products, such as the moisture content, water activity and texture, were investigated in terms of X-ray diffraction and thermogravimetric analysis.					
35408623	3	56	theme	relaxation	306:315	arg1	experiments					317:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments	286:327	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	2	57	theme	different	193:201	arg1	sugar					203:207	different sugar	193:207	different sugar	193:207	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	3	58	theme	sugar	470:474	arg1	types					476:480	different sugar types	460:480	different sugar types	460:480	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	0	59	theme	Different	64:72	arg1	Types					74:78	Different Types	64:78	Different Types of Sugar	64:87	Water Dynamics in Starch Based Confectionery Products including Different Types of Sugar.					
35408623	2	60	theme	protein	239:245	arg1	isolate					247:253	soy protein isolate	235:253	soy protein isolate (SPI)	235:259	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	2	60	theme	protein	239:245	arg1	SPI					256:258	SPI	256:258	SPI	256:258	In addition to using different sugar, starch was replaced with soy protein isolate (SPI) in some of the products.					
35408623	3	61	from	KHz	409:411	arg1	range					396:400	a broad frequency range	378:400	a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems	378:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35408623	3	62	theme	types	476:480	arg1	influence					447:455	the influence	443:455	the influence of different sugar types and SPI on the dynamics of water in composite gel systems	443:538	1H NMR spin-lattice relaxation experiments were performed for the collection of products in a broad frequency range from 4 KHz to 30 MHz to get insight into the influence of different sugar types and SPI on the dynamics of water in composite gel systems.					
35779652	0	0	theme	noncompressible	124:138	arg1	hemorrhage					140:149	noncompressible hemorrhage	124:149	noncompressible hemorrhage	124:149	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	4	1	theme	rapid	1058:1062	arg1	recovery					1092:1099	rapid water/blood-triggered shape recovery	1058:1099	rapid water/blood-triggered shape recovery	1058:1099	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	1	theme	rapid	1058:1062	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	6	2	dep	incision	1448:1455	arg1	bleeding					1457:1464	bleeding	1457:1464	bleeding	1457:1464	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	6	3	theme	bleeding	1394:1401	arg1	time					1403:1406	the bleeding time	1390:1406	the bleeding time	1390:1406	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	2	4	theme	crosslinkers	427:438	arg1	use					410:412	the use	406:412	the use of non-toxic crosslinkers to prepare cryogels for noncompressible hemorrhage	406:489	However, the use of non-toxic crosslinkers to prepare cryogels for noncompressible hemorrhage remains a challenge.					
35779652	6	5	theme	liver	1470:1474	arg1	hemorrhage					1492:1501	liver noncompressible hemorrhage	1470:1501	liver noncompressible hemorrhage	1470:1501	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	3	6	theme	polydopamine	721:732	arg1	PDA-NPs					749:755	PDA-NPs	749:755	PDA-NPs	749:755	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	6	theme	polydopamine	721:732	arg1	nanoparticles					734:746	polydopamine nanoparticles	721:746	polydopamine nanoparticles (PDA-NPs)	721:756	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	6	7	theme	incision	1448:1455	arg1	volume					1432:1437	the bleeding volume	1419:1437	the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage	1419:1501	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	1	8	theme	sharp	220:224	arg1	objects					226:232	sharp objects	220:232	sharp objects	220:232	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	3	9	theme	good	642:645	arg1	properties					658:667	the good hemostatic properties	638:667	the good hemostatic properties of chitosan (CS) and human-like collagen (HLC)	638:714	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	10	theme	biocompatible	597:609	arg1	crosslinker					611:621	a biocompatible crosslinker	595:621	a biocompatible crosslinker	595:621	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	10	theme	biocompatible	597:609	arg1	dextran					577:583	oxidized dextran	568:583	oxidized dextran (ODex)	568:590	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	1	11	theme	noncompressible	317:331	arg1	applications					344:355	noncompressible hemorrhage applications	317:355	noncompressible hemorrhage applications owing to their shape-memory properties	317:394	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	5	12	theme	procoagulant	1189:1200	arg1	ability					1202:1208	strong procoagulant ability	1182:1208	strong procoagulant ability	1182:1208	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	4	13	theme	water/blood-triggered	1064:1084	arg1	recovery					1092:1099	rapid water/blood-triggered shape recovery	1058:1099	rapid water/blood-triggered shape recovery	1058:1099	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	13	theme	water/blood-triggered	1064:1084	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	1	14	theme	hemorrhage	333:342	arg1	applications					344:355	noncompressible hemorrhage applications	317:355	noncompressible hemorrhage applications owing to their shape-memory properties	317:394	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	4	15	theme	mechanical	1030:1039	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	15	theme	mechanical	1030:1039	arg1	performance					1041:1051	robust mechanical performance	1023:1051	robust mechanical performance	1023:1051	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	16	theme	CS/HLC/ODex/PDA-NPs	888:906	arg1	cryogels					915:922	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels	884:922	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels	884:922	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	7	17	theme	good	1530:1533	arg1	biocompatibility					1535:1550	good biocompatibility	1530:1550	good biocompatibility	1530:1550	Meanwhile, CHOP exhibited good biocompatibility and biodegradability, and could promote wound healing.					
35779652	5	18	theme	strong	1182:1187	arg1	ability					1202:1208	strong procoagulant ability	1182:1208	strong procoagulant ability	1182:1208	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	0	19	theme	wound	155:159	arg1	healing					161:167	wound healing	155:167	wound healing	155:167	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	6	20	theme	liver	1442:1446	arg1	incision					1448:1455	liver incision bleeding and liver noncompressible hemorrhage	1442:1501	incision	1448:1455	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	2	21	theme	noncompressible	464:478	arg1	hemorrhage					480:489	noncompressible hemorrhage	464:489	noncompressible hemorrhage	464:489	However, the use of non-toxic crosslinkers to prepare cryogels for noncompressible hemorrhage remains a challenge.					
35779652	5	22	theme	high	1211:1214	arg1	adhesion					1216:1223	high adhesion	1211:1223	high adhesion to blood cells and fibrinogen	1211:1253	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	6	23	theme	hemorrhage	1492:1501	arg1	volume					1432:1437	the bleeding volume	1419:1437	the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage	1419:1501	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	5	24	dep	In	1102:1103	arg1	vitro					1105:1109	vitro	1105:1109	vitro	1105:1109	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	0	25	theme	Oxidized	0:7	arg1	dextran					9:15	Oxidized dextran	0:15	Oxidized dextran	0:15	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	8	26	theme	hemostatic	1668:1677	arg1	dressing					1679:1686	a promising hemostatic dressing	1656:1686	a promising hemostatic dressing	1656:1686	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	8	26	theme	hemostatic	1668:1677	arg1	cryogels					1639:1646	CHOP cryogels	1634:1646	CHOP cryogels	1634:1646	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	1	27	theme	higher	243:248	arg1	mortality					257:265	higher trauma mortality	243:265	higher trauma mortality	243:265	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	0	28	theme	polysaccharide/protein/polydopamine	29:63	arg1	cryogels					75:82	polysaccharide/protein/polydopamine composite cryogels	29:82	polysaccharide/protein/polydopamine composite cryogels	29:82	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	3	29	theme	shape	797:801	arg1	speed					812:816	the shape recovery speed	793:816	the shape recovery speed of the cryogels	793:832	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	4	30	theme	powerful	981:988	arg1	capacity					1013:1020	powerful water/blood absorption capacity	981:1020	powerful water/blood absorption capacity	981:1020	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	30	theme	powerful	981:988	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	3	31	theme	hemostatic	860:869	arg1	performance					871:881	their hemostatic performance	854:881	their hemostatic performance	854:881	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	6	32	theme	hemostatic	1327:1336	arg1	tests					1338:1342	In vivo hemostatic tests	1319:1342	In vivo hemostatic tests	1319:1342	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	1	33	theme	trauma	250:255	arg1	mortality					257:265	higher trauma mortality	243:265	higher trauma mortality	243:265	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	3	34	theme	collagen	701:708	arg1	properties					658:667	the good hemostatic properties	638:667	the good hemostatic properties of chitosan (CS) and human-like collagen (HLC)	638:714	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	2	35	theme	non-toxic	417:425	arg1	crosslinkers					427:438	non-toxic crosslinkers	417:438	non-toxic crosslinkers	417:438	However, the use of non-toxic crosslinkers to prepare cryogels for noncompressible hemorrhage remains a challenge.					
35779652	3	36	theme	cryogels	539:546	arg1	series					529:534	a series	527:534	a series of cryogels	527:546	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	4	37	theme	shape	1086:1090	arg1	recovery					1092:1099	rapid water/blood-triggered shape recovery	1058:1099	rapid water/blood-triggered shape recovery	1058:1099	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	37	theme	shape	1086:1090	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	3	38	theme	oxidized	568:575	arg1	crosslinker					611:621	a biocompatible crosslinker	595:621	a biocompatible crosslinker	595:621	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	38	theme	oxidized	568:575	arg1	ODex					586:589	ODex	586:589	ODex	586:589	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	38	theme	oxidized	568:575	arg1	dextran					577:583	oxidized dextran	568:583	oxidized dextran (ODex)	568:590	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	4	39	theme	absorption	1002:1011	arg1	capacity					1013:1020	powerful water/blood absorption capacity	981:1020	powerful water/blood absorption capacity	981:1020	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	39	theme	absorption	1002:1011	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	5	40	theme	In	1102:1103	arg1	coagulation					1111:1121	In vitro coagulation and coagulation mechanism tests	1102:1153	coagulation	1111:1121	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	0	41	theme	composite	65:73	arg1	cryogels					75:82	polysaccharide/protein/polydopamine composite cryogels	29:82	polysaccharide/protein/polydopamine composite cryogels	29:82	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	1	42	theme	shape-memory	372:383	arg1	properties					385:394	their shape-memory properties	366:394	their shape-memory properties	366:394	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	4	43	theme	water/blood	990:1000	arg1	capacity					1013:1020	powerful water/blood absorption capacity	981:1020	powerful water/blood absorption capacity	981:1020	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	43	theme	water/blood	990:1000	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	6	44	theme	bleeding	1423:1430	arg1	volume					1432:1437	the bleeding volume	1419:1437	the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage	1419:1501	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	3	45	theme	cryogels	825:832	arg1	speed					812:816	the shape recovery speed	793:816	the shape recovery speed of the cryogels	793:832	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	7	46	theme	wound	1592:1596	arg1	healing					1598:1604	wound healing	1592:1604	wound healing	1592:1604	Meanwhile, CHOP exhibited good biocompatibility and biodegradability, and could promote wound healing.					
35779652	4	47	theme	robust	1023:1028	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	47	theme	robust	1023:1028	arg1	performance					1041:1051	robust mechanical performance	1023:1051	robust mechanical performance	1023:1051	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	0	48	theme	multiple	89:96	arg1	efficacies					109:118	multiple hemostatic efficacies	89:118	multiple hemostatic efficacies for noncompressible hemorrhage and wound healing	89:167	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35779652	4	49	theme	interconnected	943:956	arg1	recovery					1092:1099	rapid water/blood-triggered shape recovery	1058:1099	rapid water/blood-triggered shape recovery	1058:1099	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	49	theme	interconnected	943:956	arg1	capacity					1013:1020	powerful water/blood absorption capacity	981:1020	powerful water/blood absorption capacity	981:1020	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	49	theme	interconnected	943:956	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	49	theme	interconnected	943:956	arg1	performance					1041:1051	robust mechanical performance	1023:1051	robust mechanical performance	1023:1051	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	3	50	theme	human-like	690:699	arg1	collagen					701:708	human-like collagen	690:708	human-like collagen (HLC)	690:714	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	3	50	theme	human-like	690:699	arg1	HLC					711:713	HLC	711:713	HLC	711:713	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	1	51	contain	have	281:284	arg1	cryogels					272:279	cryogels	272:279	cryogels	272:279	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	1	51	contain	have	281:284	arg2	potential					292:300	great potential	286:300	great potential	286:300	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	5	52	theme	blood	1228:1232	arg1	cells					1234:1238	blood cells	1228:1238	blood cells	1228:1238	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	3	53	theme	recovery	803:810	arg1	speed					812:816	the shape recovery speed	793:816	the shape recovery speed of the cryogels	793:832	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	5	54	theme	coagulation	1127:1137	arg1	tests					1149:1153	In vitro coagulation and coagulation mechanism tests	1102:1153	tests	1149:1153	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	3	55	theme	hemostatic	647:656	arg1	properties					658:667	the good hemostatic properties	638:667	the good hemostatic properties of chitosan (CS) and human-like collagen (HLC)	638:714	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	1	56	theme	Noncompressible	170:184	arg1	hemorrhage					186:195	Noncompressible hemorrhage	170:195	Noncompressible hemorrhage caused by gunshots and sharp objects	170:232	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	6	57	theme	noncompressible	1476:1490	arg1	hemorrhage					1492:1501	liver noncompressible hemorrhage	1470:1501	liver noncompressible hemorrhage	1470:1501	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	5	58	theme	mechanism	1139:1147	arg1	tests					1149:1153	In vitro coagulation and coagulation mechanism tests	1102:1153	tests	1149:1153	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	5	59	theme	intrinsic	1299:1307	arg1	pathways					1309:1316	intrinsic pathways	1299:1316	intrinsic pathways	1299:1316	In vitro coagulation and coagulation mechanism tests showed that CHOP exhibited strong procoagulant ability, high adhesion to blood cells and fibrinogen, and the capacity to activate platelets and intrinsic pathways.					
35779652	4	60	theme	macroporous	958:968	arg1	recovery					1092:1099	rapid water/blood-triggered shape recovery	1058:1099	rapid water/blood-triggered shape recovery	1058:1099	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	60	theme	macroporous	958:968	arg1	capacity					1013:1020	powerful water/blood absorption capacity	981:1020	powerful water/blood absorption capacity	981:1020	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	60	theme	macroporous	958:968	arg1	structure					970:978	a highly interconnected macroporous structure	934:978	a highly interconnected macroporous structure	934:978	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	4	60	theme	macroporous	958:968	arg1	performance					1041:1051	robust mechanical performance	1023:1051	robust mechanical performance	1023:1051	The CS/HLC/ODex/PDA-NPs (CHOP) cryogels presented a highly interconnected macroporous structure, powerful water/blood absorption capacity, robust mechanical performance, and rapid water/blood-triggered shape recovery.					
35779652	6	61	theme	In	1319:1320	arg1	tests					1338:1342	In vivo hemostatic tests	1319:1342	In vivo hemostatic tests	1319:1342	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	8	62	theme	CHOP	1634:1637	arg1	dressing					1679:1686	a promising hemostatic dressing	1656:1686	a promising hemostatic dressing	1656:1686	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	8	62	theme	CHOP	1634:1637	arg1	cryogels					1639:1646	CHOP cryogels	1634:1646	CHOP cryogels	1634:1646	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	3	63	theme	chitosan	672:679	arg1	properties					658:667	the good hemostatic properties	638:667	the good hemostatic properties of chitosan (CS) and human-like collagen (HLC)	638:714	In this study, a series of cryogels were prepared using oxidized dextran (ODex) as a biocompatible crosslinker, combined with the good hemostatic properties of chitosan (CS) and human-like collagen (HLC), and polydopamine nanoparticles (PDA-NPs) were also introduced to strengthen the shape recovery speed of the cryogels and further enhance their hemostatic performance.					
35779652	8	64	theme	promising	1658:1666	arg1	dressing					1679:1686	a promising hemostatic dressing	1656:1686	a promising hemostatic dressing	1656:1686	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	8	64	theme	promising	1658:1666	arg1	cryogels					1639:1646	CHOP cryogels	1634:1646	CHOP cryogels	1634:1646	These results suggest that CHOP cryogels will be a promising hemostatic dressing.					
35779652	6	65	dep	In	1319:1320	arg1	vivo					1322:1325	vivo	1322:1325	vivo	1322:1325	In vivo hemostatic tests indicated that CHOP could effectively shorten the bleeding time and reduce the bleeding volume of liver incision bleeding and liver noncompressible hemorrhage.					
35779652	1	66	theme	great	286:290	arg1	potential					292:300	great potential	286:300	great potential	286:300	Noncompressible hemorrhage caused by gunshots and sharp objects leads to higher trauma mortality, and cryogels have great potential in controlling noncompressible hemorrhage applications owing to their shape-memory properties.					
35779652	0	67	theme	hemostatic	98:107	arg1	efficacies					109:118	multiple hemostatic efficacies	89:118	multiple hemostatic efficacies for noncompressible hemorrhage and wound healing	89:167	Oxidized dextran crosslinked polysaccharide/protein/polydopamine composite cryogels with multiple hemostatic efficacies for noncompressible hemorrhage and wound healing.					
35605498	0	0	theme	cations	111:117	arg1	uptake					85:90	the efficient uptake	71:90	the efficient uptake of hazardous metal cations and catalysis in polluted water	71:149	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	6	1	theme	nanoparticles	1392:1404	arg1	development					1374:1384	the in situ development	1362:1384	the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol	1362:1529	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	6	2	theme	Cu2+-adsorbing	1309:1322	arg1	support					1350:1356	a support	1348:1356	a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol	1348:1529	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	6	2	theme	Cu2+-adsorbing	1309:1322	arg1	hydrogel					1324:1331	the Cu2+-adsorbing hydrogel	1305:1331	the Cu2+-adsorbing hydrogel	1305:1331	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	1	3	theme	reliable	361:368	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	3	4	theme	multi-ion	791:799	arg1	system					812:817	a multi-ion adsorption system	789:817	a multi-ion adsorption system	789:817	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	0	5	theme	metal	105:109	arg1	cations					111:117	hazardous metal cations	95:117	hazardous metal cations	95:117	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	3	6	with	cations	849:855	arg1	selectivity					878:888	slightly higher selectivity	862:888	slightly higher selectivity for Cu2+	862:897	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	6	7	dep	in	1366:1367	arg1	situ					1369:1372	situ	1369:1372	situ	1369:1372	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	1	8	theme	novel	175:179	arg1	group					207:211	a novel ecofriendly bilayer-amine group	173:211	a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	173:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	3	9	theme	mixed	837:841	arg1	cations					849:855	mixed metal cations	837:855	mixed metal cations with slightly higher selectivity for Cu2+	837:897	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	3	10	theme	adsorption	801:810	arg1	system					812:817	a multi-ion adsorption system	789:817	a multi-ion adsorption system	789:817	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	0	11	theme	catalysis	123:131	arg1	uptake					85:90	the efficient uptake	71:90	the efficient uptake of hazardous metal cations and catalysis in polluted water	71:149	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	2	12	theme	Zn2+	560:563	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	3	13	theme	metal	843:847	arg1	cations					849:855	mixed metal cations	837:855	mixed metal cations with slightly higher selectivity for Cu2+	837:897	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	5	14	theme	metal	1226:1230	arg1	adsorption					1236:1245	>40% metal ion adsorption	1221:1245	>40% metal ion adsorption	1221:1245	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	2	15	theme	abundant	474:481	arg1	sites					494:498	abundant adsorptive sites	474:498	abundant adsorptive sites	474:498	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	0	16	from	uptake	85:90	arg1	water					145:149	polluted water	136:149	polluted water	136:149	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	2	17	theme	~277.7	602:607	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	18	theme	4-NP	1682:1685	arg1	effluents					1696:1704	4-NP polluted effluents	1682:1704	4-NP polluted effluents	1682:1704	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	5	19	theme	ion	1232:1234	arg1	adsorption					1236:1245	>40% metal ion adsorption	1221:1245	>40% metal ion adsorption	1221:1245	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	0	20	theme	polluted	136:143	arg1	water					145:149	polluted water	136:149	polluted water	136:149	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	2	21	theme	~434.8	594:599	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	6	22	theme	4-nitrophenol	1493:1505	arg1	transformation					1475:1488	the transformation	1471:1488	the transformation of 4-nitrophenol (4-NP) to 4-aminophenol	1471:1529	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	4	23	theme	metal	1134:1138	arg1	ions					1140:1143	metal ions	1134:1143	metal ions	1134:1143	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	24	theme	ecofriendly	181:191	arg1	group					207:211	a novel ecofriendly bilayer-amine group	173:211	a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	173:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	4	25	theme	binding	1006:1012	arg1	mechanism					1014:1022	a plausible binding mechanism	994:1022	a plausible binding mechanism of metal cations on the as-prepared hydrogel	994:1067	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	26	theme	effective	374:382	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	5	27	theme	>40	1221:1223	arg1	%					1224:1224	%	1224:1224	%	1224:1224	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	1	28	theme	nickel	430:435	arg1	ions					444:447	nickel (Ni2+) ions	430:447	nickel (Ni2+) ions	430:447	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	7	29	theme	effluents	1696:1704	arg1	remediation					1643:1653	remediation	1643:1653	remediation of heavy metal cations and 4-NP polluted effluents	1643:1704	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	1	30	theme	bilayer-amine	193:205	arg1	group					207:211	a novel ecofriendly bilayer-amine group	173:211	a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	173:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	0	31	theme	cellulose-chitosan	29:46	arg1	hydrogel					58:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel	0:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.	0:150	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	6	32	theme	Cu	1389:1390	arg1	nanoparticles					1392:1404	Cu nanoparticles	1389:1404	Cu nanoparticles	1389:1404	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	4	33	theme	spectrometric	970:982	arg1	analyses					984:991	Fourier-transform-infrared spectrometric analyses	943:991	Fourier-transform-infrared spectrometric analyses	943:991	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	4	34	theme	X-ray	919:923	arg1	photoelectron					925:937	X-ray photoelectron	919:937	X-ray photoelectron	919:937	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	3	35	theme	higher	871:876	arg1	selectivity					878:888	slightly higher selectivity	862:888	slightly higher selectivity for Cu2+	862:897	In a multi-ion adsorption system, hydrogel removes mixed metal cations with slightly higher selectivity for Cu2+.					
35605498	0	36	theme	Amine-bilayer-functionalized	0:27	arg1	hydrogel					58:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel	0:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.	0:150	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	7	37	theme	heavy	1658:1662	arg1	cations					1670:1676	heavy metal cations	1658:1676	heavy metal cations	1658:1676	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	2	38	theme	Ni2+	570:573	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	1	39	theme	Ni2+	438:441	arg1	ions					444:447	nickel (Ni2+) ions	430:447	nickel (Ni2+) ions	430:447	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	2	40	theme	Langmuir	755:762	arg1	models					764:769	Langmuir models	755:769	Langmuir models	755:769	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	41	theme	metal	1664:1668	arg1	cations					1670:1676	heavy metal cations	1658:1676	heavy metal cations	1658:1676	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	2	42	theme	MCC-PDA-PEI/CS-PDA-PEI	505:526	arg1	hydrogel					528:535	the MCC-PDA-PEI/CS-PDA-PEI hydrogel	501:535	the MCC-PDA-PEI/CS-PDA-PEI hydrogel	501:535	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	2	43	theme	~261.8 mg/g	614:624	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	4	44	theme	hydrogel	1103:1110	arg1	groups					1123:1128	hydrogel functional groups	1103:1128	hydrogel functional groups	1103:1128	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	45	theme	microcrystalline	226:241	arg1	hydrogel					273:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	0	46	theme	composite	48:56	arg1	hydrogel					58:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel	0:65	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.	0:150	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	7	47	theme	highly-efficient	1586:1601	arg1	ecofriendly					1559:1569	a novel ecofriendly	1551:1569	a novel ecofriendly	1551:1569	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	6	48	theme	catalytic	1430:1438	arg1	performance					1440:1450	excellent catalytic performance	1420:1450	excellent catalytic performance	1420:1450	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	7	49	theme	cations	1670:1676	arg1	remediation					1643:1653	remediation	1643:1653	remediation of heavy metal cations and 4-NP polluted effluents	1643:1704	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	1	50	theme	cellulose	243:251	arg1	hydrogel					273:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	4	51	theme	plausible	996:1004	arg1	mechanism					1014:1022	a plausible binding mechanism	994:1022	a plausible binding mechanism of metal cations on the as-prepared hydrogel	994:1067	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	52	theme	copper	398:403	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	2	53	with	system	668:673	arg1	kinetics					695:702	the adsorption kinetics	680:702	the adsorption kinetics	680:702	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	4	54	from	mechanism	1014:1022	arg1	hydrogel					1060:1067	the as-prepared hydrogel	1044:1067	the as-prepared hydrogel	1044:1067	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	5	55	theme	%	1224:1224	arg1	adsorption					1236:1245	>40% metal ion adsorption	1221:1245	>40% metal ion adsorption	1221:1245	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	4	56	theme	as-prepared	1048:1058	arg1	hydrogel					1060:1067	the as-prepared hydrogel	1044:1067	the as-prepared hydrogel	1044:1067	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	57	theme	ions	444:447	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	1	58	theme	MCC	254:256	arg1	hydrogel					273:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	6	59	theme	excellent	1420:1428	arg1	performance					1440:1450	excellent catalytic performance	1420:1450	excellent catalytic performance	1420:1450	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	2	60	theme	adsorptive	483:492	arg1	sites					494:498	abundant adsorptive sites	474:498	abundant adsorptive sites	474:498	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	2	61	theme	Cu2+	554:557	arg1	adsorbabilities					575:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities	544:589	excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively	544:638	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	62	theme	novel	1553:1557	arg1	ecofriendly					1559:1569	a novel ecofriendly	1551:1569	a novel ecofriendly	1551:1569	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	2	63	theme	single-ion	646:655	arg1	system					668:673	a single-ion adsorption system	644:673	a single-ion adsorption system with the adsorption kinetics	644:702	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	64	theme	reusable	1572:1579	arg1	ecofriendly					1559:1569	a novel ecofriendly	1551:1569	a novel ecofriendly	1551:1569	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	0	65	theme	efficient	75:83	arg1	uptake					85:90	the efficient uptake	71:90	the efficient uptake of hazardous metal cations and catalysis in polluted water	71:149	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	5	66	theme	adsorption/desorption	1164:1184	arg1	experiments					1186:1196	the repetitive adsorption/desorption experiments	1149:1196	the repetitive adsorption/desorption experiments	1149:1196	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	2	67	theme	excellent	544:552	arg1	Cu2+					554:557	excellent Cu2+	544:557	excellent Cu2+	544:557	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	68	dep	reusable	1572:1579	arg1	adsorbent					1603:1611	adsorbent	1603:1611	adsorbent	1603:1611	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	1	69	theme	zinc	413:416	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	2	70	theme	adsorption	657:666	arg1	system					668:673	a single-ion adsorption system	644:673	a single-ion adsorption system with the adsorption kinetics	644:702	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	2	71	theme	adsorption	684:693	arg1	kinetics					695:702	the adsorption kinetics	680:702	the adsorption kinetics	680:702	Owing to abundant adsorptive sites, the MCC-PDA-PEI/CS-PDA-PEI hydrogel showed excellent Cu2+, Zn2+, and Ni2+ adsorbabilities of ~434.8, ~277.7, and ~261.8 mg/g, respectively, in a single-ion adsorption system with the adsorption kinetics and isotherm complied with pseudo-second-order and Langmuir models, respectively.					
35605498	7	72	theme	polluted	1687:1694	arg1	effluents					1696:1704	4-NP polluted effluents	1682:1704	4-NP polluted effluents	1682:1704	This work provides a novel ecofriendly, reusable, and highly-efficient adsorbent, as well as a biocatalyst for remediation of heavy metal cations and 4-NP polluted effluents.					
35605498	6	73	theme	in	1366:1367	arg1	development					1374:1384	the in situ development	1362:1384	the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol	1362:1529	Furthermore, the Cu2+-adsorbing hydrogel could serve as a support for the in situ development of Cu nanoparticles, which showed excellent catalytic performance as demonstrated by the transformation of 4-nitrophenol (4-NP) to 4-aminophenol.					
35605498	1	74	theme	/chitosan	258:266	arg1	hydrogel					273:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	0	75	theme	hazardous	95:103	arg1	cations					111:117	hazardous metal cations	95:117	hazardous metal cations	95:117	Amine-bilayer-functionalized cellulose-chitosan composite hydrogel for the efficient uptake of hazardous metal cations and catalysis in polluted water.					
35605498	1	76	from	effluents	454:462	arg1	extraction					384:393	reliable and effective extraction	361:393	reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents	361:462	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35605498	5	77	theme	desorption	1251:1260	arg1	capacities					1262:1271	desorption capacities	1251:1271	desorption capacities	1251:1271	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	4	78	theme	Fourier-transform-infrared	943:968	arg1	analyses					984:991	Fourier-transform-infrared spectrometric analyses	943:991	Fourier-transform-infrared spectrometric analyses	943:991	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	5	79	theme	repetitive	1153:1162	arg1	experiments					1186:1196	the repetitive adsorption/desorption experiments	1149:1196	the repetitive adsorption/desorption experiments	1149:1196	In the repetitive adsorption/desorption experiments, the hydrogel retained >40% metal ion adsorption and desorption capacities after four cycles.					
35605498	4	80	theme	cations	1033:1039	arg1	mechanism					1014:1022	a plausible binding mechanism	994:1022	a plausible binding mechanism of metal cations on the as-prepared hydrogel	994:1067	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	4	81	theme	metal	1027:1031	arg1	cations					1033:1039	metal cations	1027:1039	metal cations	1027:1039	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	4	82	theme	functional	1112:1121	arg1	groups					1123:1128	hydrogel functional groups	1103:1128	hydrogel functional groups	1103:1128	In accordance with X-ray photoelectron and Fourier-transform-infrared spectrometric analyses, a plausible binding mechanism of metal cations on the as-prepared hydrogel was proposed by chelation between hydrogel functional groups and metal ions.					
35605498	1	83	theme	CS	269:270	arg1	hydrogel					273:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	microcrystalline cellulose (MCC)/chitosan (CS) hydrogel	226:280	Herein, we represent a novel ecofriendly bilayer-amine group incorporated microcrystalline cellulose (MCC)/chitosan (CS) hydrogel, fabricated via integrating polydopamine (PDA) and polyethyleneimine (PEI) for reliable and effective extraction of copper (Cu2+), zinc (Zn2+), and nickel (Ni2+) ions from effluents.					
35698320	4	0	theme	CS-based	534:541	arg1	material					543:550	a CS-based material	532:550	a CS-based material	532:550	Herein, we designed a CS-based material via integrating CS into the network of polyimine (PI), which shows thermomechanical processability similar to plastics.					
35698320	7	1	theme	materials	1123:1131	arg1	production					1093:1102	the production	1089:1102	the production of next-generation materials	1089:1131	Notably, CPs can be easily degraded and 100% recycled for the production of next-generation materials.					
35698320	8	2	theme	sustainable	1195:1205	arg1	plastic					1230:1236	plastic	1230:1236	plastic	1230:1236	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	8	2	theme	sustainable	1195:1205	arg1	materials					1215:1223	green and sustainable biomass materials	1185:1223	green and sustainable biomass materials	1185:1223	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	6	3	theme	multi-layer	1007:1017	arg1	laminating					1019:1028	multi-layer laminating	1007:1028	multi-layer laminating	1007:1028	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	8	4	theme	alternative	1156:1166	arg1	route					1168:1172	an alternative route	1153:1172	an alternative route to produce green and sustainable biomass materials as a plastic substitute	1153:1247	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	6	5	theme	excellent	895:903	arg1	stability					922:930	excellent thermal/chemical stability	895:930	excellent thermal/chemical stability	895:930	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	1	6	theme	sustainable	207:217	arg1	materials					230:238	sustainable substitute materials	207:238	sustainable substitute materials	207:238	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	2	7	theme	potential	339:347	arg1	candidate					349:357	a potential candidate	337:357	a potential candidate for plastic substitution	337:382	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	2	7	theme	potential	339:347	arg1	chitosan					300:307	chitosan	300:307	chitosan (CS)	300:312	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	3	8	theme	CS-based	401:408	arg1	materials					410:418	CS-based materials	401:418	CS-based materials	401:418	Conventionally, CS-based materials are fabricated through a solution-processing procedure due to the high crystallinity of CS.					
35698320	5	9	theme	dynamic	714:720	arg1	bond					728:731	dynamic imine bond	714:731	dynamic imine bond	714:731	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	5	10	theme	dynamic	788:794	arg1	network					806:812	a thermo-processable dynamic composite network	767:812	a thermo-processable dynamic composite network	767:812	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	6	11	theme	mechanical	870:879	arg1	re-healing					978:987	re-healing	978:987	re-healing	978:987	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	11	theme	mechanical	870:879	arg1	performances					881:892	exceptional mechanical performances	858:892	exceptional mechanical performances	858:892	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	11	theme	mechanical	870:879	arg1	reprocessing					990:1001	reprocessing	990:1001	reprocessing	990:1001	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	11	theme	mechanical	870:879	arg1	laminating					1019:1028	multi-layer laminating	1007:1028	multi-layer laminating	1007:1028	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	12	dep	plastic	830:836	arg1	substitutes					838:848	substitutes	838:848	substitutes	838:848	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	3	13	theme	high	486:489	arg1	crystallinity					491:503	the high crystallinity	482:503	the high crystallinity of CS	482:509	Conventionally, CS-based materials are fabricated through a solution-processing procedure due to the high crystallinity of CS.					
35698320	5	14	theme	composite	796:804	arg1	network					806:812	a thermo-processable dynamic composite network	767:812	a thermo-processable dynamic composite network	767:812	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	8	15	dep	plastic	1230:1236	arg1	substitute					1238:1247	substitute	1238:1247	substitute	1238:1247	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	6	16	theme	exceptional	858:868	arg1	re-healing					978:987	re-healing	978:987	re-healing	978:987	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	16	theme	exceptional	858:868	arg1	performances					881:892	exceptional mechanical performances	858:892	exceptional mechanical performances	858:892	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	16	theme	exceptional	858:868	arg1	reprocessing					990:1001	reprocessing	990:1001	reprocessing	990:1001	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	16	theme	exceptional	858:868	arg1	laminating					1019:1028	multi-layer laminating	1007:1028	multi-layer laminating	1007:1028	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	1	17	theme	increasing	111:120	arg1	burden					136:141	The increasing environmental burden	107:141	The increasing environmental burden generated by disposable plastic wastes	107:180	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	1	18	theme	materials	230:238	arg1	development					192:202	the development	188:202	the development of sustainable substitute materials	188:238	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	0	19	theme	chitosan-based	19:32	arg1	plastic					34:40	Thermo-processable chitosan-based plastic	0:40	Thermo-processable chitosan-based plastic	0:40	Thermo-processable chitosan-based plastic substitute with self-adaptiveness and closed-loop recyclability.					
35698320	5	20	theme	Strong	672:677	arg1	interactions					679:690	Strong interactions	672:690	Strong interactions	672:690	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	1	21	theme	environmental	122:134	arg1	burden					136:141	The increasing environmental burden	107:141	The increasing environmental burden generated by disposable plastic wastes	107:180	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	0	22	theme	Thermo-processable	0:17	arg1	plastic					34:40	Thermo-processable chitosan-based plastic	0:40	Thermo-processable chitosan-based plastic	0:40	Thermo-processable chitosan-based plastic substitute with self-adaptiveness and closed-loop recyclability.					
35698320	4	23	theme	polyimine	591:599	arg1	network					580:586	the network	576:586	the network	576:586	Herein, we designed a CS-based material via integrating CS into the network of polyimine (PI), which shows thermomechanical processability similar to plastics.					
35698320	1	24	theme	emergent	243:250	arg1	task					252:255	an emergent task	240:255	an emergent task	240:255	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	stability					922:930	excellent thermal/chemical stability	895:930	excellent thermal/chemical stability	895:930	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	laminating					1019:1028	multi-layer laminating	1007:1028	multi-layer laminating	1007:1028	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	re-healing					978:987	re-healing	978:987	re-healing	978:987	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	performances					881:892	exceptional mechanical performances	858:892	exceptional mechanical performances	858:892	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	series					939:944	a series	937:944	a series of self-adaptiveness	937:965	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	6	25	theme	self-adaptiveness	949:965	arg1	reprocessing					990:1001	reprocessing	990:1001	reprocessing	990:1001	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	7	26	dep	%	1074:1074	arg1	100					1071:1073	100	1071:1073	100	1071:1073	Notably, CPs can be easily degraded and 100% recycled for the production of next-generation materials.					
35698320	2	27	theme	plastic	363:369	arg1	substitution					371:382	plastic substitution	363:382	plastic substitution	363:382	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	8	28	theme	green	1185:1189	arg1	plastic					1230:1236	plastic	1230:1236	plastic	1230:1236	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	8	28	theme	green	1185:1189	arg1	materials					1215:1223	green and sustainable biomass materials	1185:1223	green and sustainable biomass materials	1185:1223	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	2	29	theme	abundant	277:284	arg1	bioresources					286:297	the most abundant bioresources	268:297	the most abundant bioresources	268:297	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	3	30	theme	due	475:477	arg1	procedure					465:473	a solution-processing procedure	443:473	a solution-processing procedure due to the high crystallinity of CS	443:509	Conventionally, CS-based materials are fabricated through a solution-processing procedure due to the high crystallinity of CS.					
35698320	5	31	theme	thermo-processable	769:786	arg1	network					806:812	a thermo-processable dynamic composite network	767:812	a thermo-processable dynamic composite network	767:812	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	3	32	theme	CS	508:509	arg1	crystallinity					491:503	the high crystallinity	482:503	the high crystallinity of CS	482:509	Conventionally, CS-based materials are fabricated through a solution-processing procedure due to the high crystallinity of CS.					
35698320	0	33	theme	closed-loop	80:90	arg1	recyclability					92:104	closed-loop recyclability	80:104	closed-loop recyclability	80:104	Thermo-processable chitosan-based plastic substitute with self-adaptiveness and closed-loop recyclability.					
35698320	5	34	theme	imine	722:726	arg1	bond					728:731	dynamic imine bond	714:731	dynamic imine bond	714:731	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	1	35	theme	disposable	156:165	arg1	wastes					175:180	disposable plastic wastes	156:180	disposable plastic wastes	156:180	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	3	36	theme	solution-processing	445:463	arg1	procedure					465:473	a solution-processing procedure	443:473	a solution-processing procedure due to the high crystallinity of CS	443:509	Conventionally, CS-based materials are fabricated through a solution-processing procedure due to the high crystallinity of CS.					
35698320	1	37	dep	materials	230:238	arg1	substitute					219:228	substitute	219:228	substitute	219:228	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	1	38	theme	plastic	167:173	arg1	wastes					175:180	disposable plastic wastes	156:180	disposable plastic wastes	156:180	The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task.					
35698320	7	39	theme	next-generation	1107:1121	arg1	materials					1123:1131	next-generation materials	1107:1131	next-generation materials	1107:1131	Notably, CPs can be easily degraded and 100% recycled for the production of next-generation materials.					
35698320	8	40	theme	biomass	1207:1213	arg1	plastic					1230:1236	plastic	1230:1236	plastic	1230:1236	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	8	40	theme	biomass	1207:1213	arg1	materials					1215:1223	green and sustainable biomass materials	1185:1223	green and sustainable biomass materials	1185:1223	This work provides an alternative route to produce green and sustainable biomass materials as a plastic substitute.					
35698320	5	41	theme	hydrogen	737:744	arg1	bond					746:749	hydrogen bond	737:749	hydrogen bond	737:749	Strong interactions were achieved through dynamic imine bond and hydrogen bond and thus formed a thermo-processable dynamic composite network.					
35698320	4	42	theme	thermomechanical	619:634	arg1	processability					636:649	thermomechanical processability	619:649	thermomechanical processability similar to plastics	619:669	Herein, we designed a CS-based material via integrating CS into the network of polyimine (PI), which shows thermomechanical processability similar to plastics.					
35698320	6	43	theme	thermal/chemical	905:920	arg1	stability					922:930	excellent thermal/chemical stability	895:930	excellent thermal/chemical stability	895:930	These CS-based plastic substitutes exhibit exceptional mechanical performances, excellent thermal/chemical stability, and a series of self-adaptiveness, including re-healing, reprocessing and multi-layer laminating.					
35698320	2	44	theme	bioresources	286:297	arg1	chitosan					300:307	chitosan	300:307	chitosan (CS)	300:312	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	2	44	theme	bioresources	286:297	arg1	bioresources					286:297	the most abundant bioresources	268:297	the most abundant bioresources	268:297	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	2	44	theme	bioresources	286:297	arg1	one					261:263	one	261:263	one	261:263	As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidate for plastic substitution.					
35698320	4	45	theme	similar	651:657	arg1	processability					636:649	thermomechanical processability	619:649	thermomechanical processability similar to plastics	619:669	Herein, we designed a CS-based material via integrating CS into the network of polyimine (PI), which shows thermomechanical processability similar to plastics.					
37334819	8	0	theme	gut	1467:1469	arg1	microbiota					1471:1480	gut microbiota	1467:1480	gut microbiota	1467:1480	The dietary composition could be exploited to manage colitis by attenuating inflammation, restoring the intestinal barrier, and regulating gut microbiota.					
37334819	1	1	theme	starch	158:163	arg1	role					140:143	the role	136:143	the role of resistant starch in promoting intestinal health	136:194	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	6	2	theme	necrosis	827:834	arg1	factor-α					836:843	tumor necrosis factor-α	821:843	tumor necrosis factor-α	821:843	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	0	3	theme	C57BL/6J	84:91	arg1	Mice					93:96	C57BL/6J Mice	84:96	C57BL/6J Mice	84:96	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	6	4	from	expression	998:1007	arg1	colon					1072:1076	the colon	1068:1076	the colon	1068:1076	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	5	theme	cytokines	795:803	arg1	group					788:792	the DSS group	780:792	the DSS group	780:792	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	5	theme	cytokines	795:803	arg1	levels					805:810	cytokines levels	795:810	cytokines levels	795:810	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	6	theme	treatment	929:937	arg1	group					939:943	RS5 treatment group	925:943	RS5 treatment group	925:943	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	7	7	theme	RS5	1145:1147	arg1	treatment					1149:1157	RS5 treatment	1145:1157	RS5 treatment	1145:1157	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	6	8	from	expression	961:970	arg1	colon					1072:1076	the colon	1068:1076	the colon	1068:1076	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	2	9	from	effect	308:313	arg1	colitis					349:355	colitis	349:355	colitis	349:355	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	6	10	theme	RS5	925:927	arg1	group					939:943	RS5 treatment group	925:943	RS5 treatment group	925:943	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	7	11	theme	Bacteroides	1243:1253	arg1	abundance					1230:1238	the abundance	1226:1238	the abundance of Bacteroides	1226:1253	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	4	12	theme	sodium-induced	452:465	arg1	colitis					467:473	dextran sulfate sodium-induced colitis	436:473	dextran sulfate sodium-induced colitis	436:473	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	5	13	with	mice	748:751	arg1	colitis					758:764	colitis	758:764	colitis	758:764	The RS5 treatment significantly attenuated weight loss, splenomegaly, colon shortening, and pathological damage in mice with colitis.					
37334819	2	14	from	mechanism	329:337	arg1	colitis					349:355	colitis	349:355	colitis	349:355	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	2	15	theme	RS5	342:344	arg1	effect					308:313	effect	308:313	effect	308:313	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	2	15	theme	RS5	342:344	arg1	mechanism					329:337	potential mechanism	319:337	potential mechanism	319:337	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	4	16	theme	sulfate	444:450	arg1	colitis					467:473	dextran sulfate sodium-induced colitis	436:473	dextran sulfate sodium-induced colitis	436:473	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	6	17	theme	mucin	1012:1016	arg1	expression					998:1007	the expression	994:1007	the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon	994:1076	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	17	theme	mucin	1012:1016	arg1	expression					961:970	the gene expression	952:970	the gene expression of interleukin-10	952:988	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	18	theme	gene	956:959	arg1	expression					961:970	the gene expression	952:970	the gene expression of interleukin-10	952:988	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	3	19	theme	lauric	413:418	arg1	acid					420:423	lauric acid	413:423	lauric acid	413:423	We prepared RS5 complexes by combining pea starch with lauric acid.					
37334819	5	20	theme	pathological	725:736	arg1	damage					738:743	pathological damage	725:743	pathological damage	725:743	The RS5 treatment significantly attenuated weight loss, splenomegaly, colon shortening, and pathological damage in mice with colitis.					
37334819	0	21	theme	Pea	0:2	arg1	Complex					23:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	1	22	theme	intestinal	178:187	arg1	health					189:194	intestinal health	178:194	intestinal health	178:194	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	0	23	theme	Starch-Lauric	4:16	arg1	Complex					23:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	6	24	from	interleukin-6	849:861	arg1	serum					871:875	serum	871:875	serum	871:875	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	24	from	interleukin-6	849:861	arg1	tissue					887:892	colon tissue	881:892	colon tissue	881:892	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	5	25	theme	colon	703:707	arg1	shortening					709:718	colon shortening	703:718	colon shortening	703:718	The RS5 treatment significantly attenuated weight loss, splenomegaly, colon shortening, and pathological damage in mice with colitis.					
37334819	6	26	theme	tumor	821:825	arg1	factor-α					836:843	tumor necrosis factor-α	821:843	tumor necrosis factor-α	821:843	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	4	27	with	Mice	426:429	arg1	colitis					467:473	dextran sulfate sodium-induced colitis	436:473	dextran sulfate sodium-induced colitis	436:473	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	3	28	theme	RS5	370:372	arg1	complexes					374:382	RS5 complexes	370:382	RS5 complexes	370:382	We prepared RS5 complexes by combining pea starch with lauric acid.					
37334819	2	29	dep	effect	308:313	arg1	the					304:306	the	304:306	the	304:306	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	4	30	theme	normal	519:524	arg1	saline					526:531	normal saline	519:531	normal saline (10 mL/kg)	519:542	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	4	30	theme	normal	519:524	arg1	10 mL/kg					534:541	10 mL/kg	534:541	10 mL/kg	534:541	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	1	31	theme	previous	103:110	arg1	documentation					112:124	The previous documentation	99:124	The previous documentation	99:124	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	4	32	theme	pea	579:581	arg1	complex					602:608	pea starch-lauric acid complex	579:608	pea starch-lauric acid complex	579:608	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	0	33	theme	Acid	18:21	arg1	Complex					23:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex	0:29	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	6	34	dep	Compare	767:773	arg1	decreased					912:920	decreased	912:920	decreased in RS5 treatment group	912:943	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	35	theme	interleukin-10	975:988	arg1	expression					998:1007	the expression	994:1007	the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon	994:1076	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	35	theme	interleukin-10	975:988	arg1	expression					961:970	the gene expression	952:970	the gene expression of interleukin-10	952:988	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	0	36	theme	Dextran	42:48	arg1	Sulfate					50:56	Dextran Sulfate	42:56	Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice	42:96	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	7	37	theme	colitis	1199:1205	arg1	mice					1207:1210	colitis mice	1199:1210	colitis mice	1199:1210	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	7	38	theme	mice	1207:1210	arg1	structure					1186:1194	the gut microbiota structure	1167:1194	the gut microbiota structure of colitis mice	1167:1210	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	4	39	theme	acid	597:600	arg1	complex					602:608	pea starch-lauric acid complex	579:608	pea starch-lauric acid complex	579:608	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	3	40	theme	pea	397:399	arg1	starch					401:406	pea starch	397:406	pea starch	397:406	We prepared RS5 complexes by combining pea starch with lauric acid.					
37334819	6	41	theme	colon	881:885	arg1	tissue					887:892	colon tissue	881:892	colon tissue	881:892	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	5	42	theme	weight	676:681	arg1	loss					683:686	weight loss	676:686	weight loss	676:686	The RS5 treatment significantly attenuated weight loss, splenomegaly, colon shortening, and pathological damage in mice with colitis.					
37334819	4	43	theme	dextran	436:442	arg1	sulfate					444:450	dextran sulfate	436:450	dextran sulfate sodium-induced colitis	436:473	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	1	44	from	effect	207:212	arg1	colitis					247:253	colitis	247:253	colitis	247:253	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	4	45	theme	starch-lauric	583:595	arg1	complex					602:608	pea starch-lauric acid complex	579:608	pea starch-lauric acid complex	579:608	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	0	46	theme	Sodium-Induced	58:71	arg1	Colitis					73:79	Dextran Sulfate Sodium-Induced Colitis	42:79	Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice	42:96	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	0	47	from	Colitis	73:79	arg1	Mice					93:96	C57BL/6J Mice	84:96	C57BL/6J Mice	84:96	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	8	48	theme	dietary	1332:1338	arg1	composition					1340:1350	The dietary composition	1328:1350	The dietary composition	1328:1350	The dietary composition could be exploited to manage colitis by attenuating inflammation, restoring the intestinal barrier, and regulating gut microbiota.					
37334819	0	49	theme	Sulfate	50:56	arg1	Colitis					73:79	Dextran Sulfate Sodium-Induced Colitis	42:79	Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice	42:96	Pea Starch-Lauric Acid Complex Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6J Mice.					
37334819	2	50	theme	potential	319:327	arg1	mechanism					329:337	potential mechanism	319:337	potential mechanism	319:337	This study aimed to investigate the effect and potential mechanism of RS5 in colitis.					
37334819	7	51	theme	gut	1171:1173	arg1	structure					1186:1194	the gut microbiota structure	1167:1194	the gut microbiota structure of colitis mice	1167:1210	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	6	52	theme	DSS	784:786	arg1	group					788:792	the DSS group	780:792	the DSS group	780:792	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	52	theme	DSS	784:786	arg1	levels					805:810	cytokines levels	795:810	cytokines levels	795:810	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	7	53	theme	microbiota	1175:1184	arg1	structure					1186:1194	the gut microbiota structure	1167:1194	the gut microbiota structure of colitis mice	1167:1210	In addition, RS5 treatment altered the gut microbiota structure of colitis mice by increasing the abundance of Bacteroides and decreasing Turicibacter, Oscillospira, Odoribacter, and Akkermansia.					
37334819	1	54	theme	starch-lipid	217:228	arg1	RS5					239:241	RS5	239:241	RS5	239:241	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	1	54	theme	starch-lipid	217:228	arg1	complex					230:236	starch-lipid complex	217:236	starch-lipid complex (RS5)	217:242	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	5	55	theme	RS5	637:639	arg1	treatment					641:649	The RS5 treatment	633:649	The RS5 treatment	633:649	The RS5 treatment significantly attenuated weight loss, splenomegaly, colon shortening, and pathological damage in mice with colitis.					
37334819	6	56	theme	zonula	1021:1026	arg1	occludens-1					1028:1038	zonula occludens-1	1021:1038	zonula occludens-1	1021:1038	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	56	theme	zonula	1021:1026	arg1	mucin					1012:1016	mucin 2	1012:1018	mucin 2	1012:1018	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	1	57	theme	complex	230:236	arg1	effect					207:212	the effect	203:212	the effect of starch-lipid complex (RS5) on colitis	203:253	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
37334819	4	58	from	effects	568:574	arg1	mice					613:616	mice	613:616	mice	613:616	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	6	59	theme	treatment	1115:1123	arg1	group					1125:1129	RS5 treatment group	1111:1129	RS5 treatment group	1111:1129	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	4	60	theme	complex	602:608	arg1	effects					568:574	the effects	564:574	the effects of pea starch-lauric acid complex on mice	564:616	Mice with dextran sulfate sodium-induced colitis were treated with either RS5 (3.25 g/kg) or normal saline (10 mL/kg) for seven days, and the effects of pea starch-lauric acid complex on mice were observed.					
37334819	6	61	from	factor-α	836:843	arg1	serum					871:875	serum	871:875	serum	871:875	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	6	61	from	factor-α	836:843	arg1	tissue					887:892	colon tissue	881:892	colon tissue	881:892	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	8	62	theme	intestinal	1432:1441	arg1	barrier					1443:1449	the intestinal barrier	1428:1449	the intestinal barrier	1428:1449	The dietary composition could be exploited to manage colitis by attenuating inflammation, restoring the intestinal barrier, and regulating gut microbiota.					
37334819	6	63	theme	RS5	1111:1113	arg1	group					1125:1129	RS5 treatment group	1111:1129	RS5 treatment group	1111:1129	Compare with the DSS group, cytokines levels, such as tumor necrosis factor-α and interleukin-6 in both serum and colon tissue was significantly decreased in RS5 treatment group, while the gene expression of interleukin-10 and the expression of mucin 2, zonula occludens-1, Occludin, and claudin-1 in the colon was significantly upregulated in RS5 treatment group.					
37334819	1	64	theme	resistant	148:156	arg1	starch					158:163	resistant starch	148:163	resistant starch	148:163	The previous documentation has shown the role of resistant starch in promoting intestinal health, while the effect of starch-lipid complex (RS5) on colitis remains unclear.					
35946873	4	0	theme	void	1081:1084	arg1	volume					1086:1091	the total void volume	1071:1091	the total void volume of the unit cell structure	1071:1118	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	1	theme	porous	994:999	arg1	materials					1001:1009	crystalline porous materials	982:1009	crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure)	982:1119	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	0	2	theme	Surface	57:63	arg1	Curvature					65:73	Every Surface Curvature	51:73	Every Surface Curvature	51:73	Surface Assessment via Grid Evaluation (SuAVE) for Every Surface Curvature and Cavity Shape.					
35946873	5	3	with	systems	1159:1165	arg1	density					1190:1196	high and low atom density	1172:1196	high and low atom density	1172:1196	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	1	4	theme	SuAVE	137:141	arg1	software					144:151	grid evaluation (SuAVE) software	120:151	grid evaluation (SuAVE) software	120:151	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	5	5	theme	high	1172:1175	arg1	density					1190:1196	high and low atom density	1172:1196	high and low atom density	1172:1196	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	0	6	theme	Cavity	79:84	arg1	Shape					86:90	Cavity Shape	79:90	Cavity Shape	79:90	Surface Assessment via Grid Evaluation (SuAVE) for Every Surface Curvature and Cavity Shape.					
35946873	4	7	dep	diameter	1023:1030	arg1	e.g.					1012:1015	e.g.	1012:1015	e.g.	1012:1015	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	8	theme	principal	934:942	arg1	moment					944:949	principal moment	934:949	principal moment of inertia	934:960	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	5	9	theme	lipid	1253:1257	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	9	theme	lipid	1253:1257	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	4	10	theme	density	729:735	arg1	profiles					737:744	density profiles	729:744	density profiles	729:744	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	3	11	theme	SuAVE	524:528	arg1	developments					508:519	novel developments	502:519	novel developments of SuAVE	502:528	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	5	12	theme	chemical	1231:1238	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	12	theme	chemical	1231:1238	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	12	theme	chemical	1231:1238	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	12	theme	chemical	1231:1238	arg1	set					1275:1277	a set	1273:1277	a set of selected metal-organic frameworks	1273:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	1	13	theme	structural	229:238	arg1	properties					240:249	structural properties	229:249	structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	229:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	14	theme	average	918:924	arg1	radius					926:931	average radius	918:931	average radius	918:931	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	15	from	version	689:695	arg1	available					663:671	available	663:671	available	663:671	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	3	16	theme	novel	502:506	arg1	developments					508:519	novel developments	502:519	novel developments of SuAVE	502:528	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	4	17	theme	total	1055:1059	arg1	area					1061:1064	total area	1055:1064	total area	1055:1064	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	18	theme	soft	887:890	arg1	matter					892:897	soft matter	887:897	soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness)	887:976	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	5	19	theme	metal-organic	1291:1303	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	20	theme	selected	1282:1289	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	4	21	theme	analyses	646:653	arg1	repertoire					612:621	the repertoire	608:621	the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure)	608:1119	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	21	theme	analyses	646:653	arg1	analyses					646:653	curvature-dependent analyses	626:653	curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	626:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	22	dep	matter	892:897	arg1	radius					926:931	average radius	918:931	average radius	918:931	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	22	dep	matter	892:897	arg1	sphericity					906:915	sphericity	906:915	sphericity	906:915	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	22	dep	matter	892:897	arg1	roundness					967:975	roundness	967:975	roundness	967:975	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	22	dep	matter	892:897	arg1	moment					944:949	principal moment	934:949	principal moment of inertia	934:960	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	23	theme	atom	338:341	arg1	coarseness					343:352	atom coarseness	338:352	atom coarseness	338:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	24	theme	curvature	825:833	arg1	angle					835:839	surface curvature angle	817:839	surface curvature angle	817:839	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	25	theme	structure	1110:1118	arg1	volume					1047:1052	internal void volume	1033:1052	internal void volume	1033:1052	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	25	theme	structure	1110:1118	arg1	area					1061:1064	total area	1055:1064	total area	1055:1064	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	25	theme	structure	1110:1118	arg1	volume					1086:1091	the total void volume	1071:1091	the total void volume of the unit cell structure	1071:1118	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	25	theme	structure	1110:1118	arg1	diameter					1023:1030	pore diameter	1018:1030	pore diameter	1018:1030	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	3	26	theme	closed	539:544	arg1	surfaces					546:553	closed surfaces	539:553	closed surfaces	539:553	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	1	27	theme	properties	240:249	arg1	calculations					213:224	the calculations	209:224	the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	209:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	28	theme	surface	817:823	arg1	angle					835:839	surface curvature angle	817:839	surface curvature angle	817:839	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	29	theme	void	1042:1045	arg1	volume					1047:1052	internal void volume	1033:1052	internal void volume	1033:1052	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	30	theme	available	663:671	arg1	analyses					646:653	curvature-dependent analyses	626:653	curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	626:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	0	31	theme	Grid	23:26	arg1	SuAVE					40:44	SuAVE	40:44	SuAVE	40:44	Surface Assessment via Grid Evaluation (SuAVE) for Every Surface Curvature and Cavity Shape.					
35946873	0	31	theme	Grid	23:26	arg1	Evaluation					28:37	Grid Evaluation	23:37	Grid Evaluation (SuAVE) for Every Surface Curvature and Cavity Shape	23:90	Surface Assessment via Grid Evaluation (SuAVE) for Every Surface Curvature and Cavity Shape.					
35946873	7	32	from	https	1441:1445	arg1	available					1426:1434	available	1426:1434	available	1426:1434	SuAVE is freely available from https://github.com/SuAVE-Software/source and https://www.biomatsite.net/.					
35946873	6	33	from	compiler	1379:1386	arg1	benefits					1363:1370	benefits	1363:1370	benefits	1363:1370	The SuAVE software v2.0 is fully parallel and benefits from a compiler that supports OpenMP.					
35946873	4	34	theme	internal	1033:1040	arg1	volume					1047:1052	internal void volume	1033:1052	internal void volume	1033:1052	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	6	35	theme	SuAVE	1321:1325	arg1	software					1327:1334	The SuAVE software v2.0	1317:1339	The SuAVE software v2.0	1317:1339	The SuAVE software v2.0 is fully parallel and benefits from a compiler that supports OpenMP.					
35946873	6	35	theme	SuAVE	1321:1325	arg1	parallel					1350:1357	parallel	1350:1357	parallel	1350:1357	The SuAVE software v2.0 is fully parallel and benefits from a compiler that supports OpenMP.					
35946873	1	36	theme	chemical	254:261	arg1	interfaces					263:272	chemical interfaces	254:272	chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	254:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	37	theme	membrane	747:754	arg1	thickness					756:764	membrane thickness	747:764	membrane thickness	747:764	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	38	theme	coarseness	343:352	arg1	asymmetry					314:322	asymmetry	314:322	asymmetry	314:322	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	1	38	theme	coarseness	343:352	arg1	level					329:333	level	329:333	level	329:333	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	1	38	theme	coarseness	343:352	arg1	composition					301:311	the chemical composition	288:311	the chemical composition	288:311	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	39	theme	previous	680:687	arg1	version					689:695	the previous version	676:695	the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	676:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	40	theme	inertia	954:960	arg1	roundness					967:975	roundness	967:975	roundness	967:975	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	40	theme	inertia	954:960	arg1	sphericity					906:915	sphericity	906:915	sphericity	906:915	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	40	theme	inertia	954:960	arg1	radius					926:931	average radius	918:931	average radius	918:931	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	40	theme	inertia	954:960	arg1	moment					944:949	principal moment	934:949	principal moment of inertia	934:960	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	41	theme	interfaces	263:272	arg1	properties					240:249	structural properties	229:249	structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	229:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	42	dep	sphericity	906:915	arg1	e.g.					900:903	e.g.	900:903	e.g.	900:903	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	43	theme	curvature-dependent	626:644	arg1	analyses					646:653	curvature-dependent analyses	626:653	curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	626:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	3	44	theme	cavity	567:572	arg1	shapes					574:579	complex cavity shapes	559:579	complex cavity shapes	559:579	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	5	45	theme	distinct	1222:1229	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	45	theme	distinct	1222:1229	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	45	theme	distinct	1222:1229	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	45	theme	distinct	1222:1229	arg1	set					1275:1277	a set	1273:1277	a set of selected metal-organic frameworks	1273:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	2	46	theme	geometry	379:386	arg1	techniques					388:397	differential geometry techniques	366:397	differential geometry techniques	366:397	It employs differential geometry techniques, enabling the representation of chemical surfaces as fully differentiable.					
35946873	5	47	theme	low	1181:1183	arg1	density					1190:1196	high and low atom density	1172:1196	high and low atom density	1172:1196	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	4	48	theme	crystalline	982:992	arg1	materials					1001:1009	crystalline porous materials	982:1009	crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure)	982:1119	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	3	49	attach	present	494:500	arg2	we					491:492	we	491:492	we	491:492	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	3	49	attach	present	494:500	arg1	article					482:488	this article	477:488	this article	477:488	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	2	50	theme	differential	366:377	arg1	techniques					388:397	differential geometry techniques	366:397	differential geometry techniques	366:397	It employs differential geometry techniques, enabling the representation of chemical surfaces as fully differentiable.					
35946873	2	51	theme	surfaces	440:447	arg1	representation					413:426	the representation	409:426	the representation of chemical surfaces	409:447	It employs differential geometry techniques, enabling the representation of chemical surfaces as fully differentiable.					
35946873	5	52	theme	chemical	1150:1157	arg1	systems					1159:1165	chemical systems	1150:1165	chemical systems with high and low atom density	1150:1196	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	2	53	theme	chemical	431:438	arg1	surfaces					440:447	chemical surfaces	431:447	chemical surfaces	431:447	It employs differential geometry techniques, enabling the representation of chemical surfaces as fully differentiable.					
35946873	4	54	theme	new	853:855	arg1	functionalities					857:871	new functionalities	853:871	new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure)	853:1119	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	7	55	dep	https	1441:1445	arg1	//github.com/SuAVE-Software/source					1447:1480	//github.com/SuAVE-Software/source	1447:1480	//github.com/SuAVE-Software/source	1447:1480	SuAVE is freely available from https://github.com/SuAVE-Software/source and https://www.biomatsite.net/.					
35946873	7	55	dep	https	1441:1445	arg1	https					1441:1445	https	1441:1445	https://github.com/SuAVE-Software/source and https://www.biomatsite.net/	1441:1512	SuAVE is freely available from https://github.com/SuAVE-Software/source and https://www.biomatsite.net/.					
35946873	7	55	dep	https	1441:1445	arg1	//www.biomatsite.net/					1492:1512	//www.biomatsite.net/	1492:1512	https://github.com/SuAVE-Software/source and https://www.biomatsite.net/	1441:1512	SuAVE is freely available from https://github.com/SuAVE-Software/source and https://www.biomatsite.net/.					
35946873	7	55	dep	https	1441:1445	arg1	https					1486:1490	https	1486:1490	https	1486:1490	SuAVE is freely available from https://github.com/SuAVE-Software/source and https://www.biomatsite.net/.					
35946873	3	56	theme	complex	559:565	arg1	shapes					574:579	complex cavity shapes	559:579	complex cavity shapes	559:579	In this article, we present novel developments of SuAVE to treat closed surfaces and complex cavity shapes.					
35946873	4	57	theme	cell	1105:1108	arg1	structure					1110:1118	the unit cell structure	1096:1118	the unit cell structure	1096:1118	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	58	theme	surface	97:103	arg1	assessment					105:114	The surface assessment	93:114	The surface assessment via grid evaluation (SuAVE) software	93:151	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	59	theme	pore	1018:1021	arg1	diameter					1023:1030	pore diameter	1018:1030	pore diameter	1018:1030	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	60	theme	chemical	292:299	arg1	composition					301:311	the chemical composition	288:311	the chemical composition	288:311	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	1	61	from	effect	186:191	arg1	calculations					213:224	the calculations	209:224	the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	209:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	5	62	theme	frameworks	1305:1314	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	62	theme	frameworks	1305:1314	arg1	set					1275:1277	a set	1273:1277	a set of selected metal-organic frameworks	1273:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	62	theme	frameworks	1305:1314	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	62	theme	frameworks	1305:1314	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	4	63	theme	unit	1100:1103	arg1	structure					1110:1118	the unit cell structure	1096:1118	the unit cell structure	1096:1118	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	5	64	theme	atom	1185:1188	arg1	density					1190:1196	high and low atom density	1172:1196	high and low atom density	1172:1196	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	4	65	theme	applicable	873:882	arg1	functionalities					857:871	new functionalities	853:871	new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure)	853:1119	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	66	theme	total	1075:1079	arg1	volume					1086:1091	the total void volume	1071:1091	the total void volume of the unit cell structure	1071:1118	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	4	67	dep	area	713:716	arg1	e.g.					707:710	e.g.	707:710	e.g.	707:710	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	5	68	dep	systems	1240:1246	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	68	dep	systems	1240:1246	arg1	set					1275:1277	a set	1273:1277	a set of selected metal-organic frameworks	1273:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	68	dep	systems	1240:1246	arg1	frameworks					1305:1314	selected metal-organic frameworks	1282:1314	selected metal-organic frameworks	1282:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	68	dep	systems	1240:1246	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	69	theme	A	1259:1259	arg1	vesicle					1261:1267	the lipid A vesicle	1249:1267	the lipid A vesicle	1249:1267	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	5	69	theme	A	1259:1259	arg1	systems					1240:1246	two distinct chemical systems	1218:1246	two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks	1218:1314	SuAVE can accurately handle chemical systems with high and low atom density as demonstrated for two distinct chemical systems: the lipid A vesicle and a set of selected metal-organic frameworks.					
35946873	1	70	theme	grid	120:123	arg1	software					144:151	grid evaluation (SuAVE) software	120:151	grid evaluation (SuAVE) software	120:151	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	71	from	available	663:671	arg1	version					689:695	the previous version	676:695	the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	676:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	72	theme	curvature	196:204	arg1	effect					186:191	the effect	182:191	the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness	182:352	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	73	theme	deuterium-order	767:781	arg1	parameters					783:792	deuterium-order parameters	767:792	deuterium-order parameters	767:792	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
35946873	1	74	theme	evaluation	125:134	arg1	software					144:151	grid evaluation (SuAVE) software	120:151	grid evaluation (SuAVE) software	120:151	The surface assessment via grid evaluation (SuAVE) software was developed to account for the effect of curvature in the calculations of structural properties of chemical interfaces regardless of the chemical composition, asymmetry, and level of atom coarseness.					
35946873	4	75	theme	SuAVE	700:704	arg1	version					689:695	the previous version	676:695	the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle)	676:840	These developments expand the repertoire of curvature-dependent analyses already available in the previous version of SuAVE (e.g., area per lipid, density profiles, membrane thickness, deuterium-order parameters, volume per lipid, and surface curvature angle) to include new functionalities applicable to soft matter (e.g., sphericity, average radius, principal moment of inertia, and roundness) and crystalline porous materials (e.g., pore diameter, internal void volume, total area, and the total void volume of the unit cell structure).					
37268071	4	0	theme	130.0°	956:961	arg1	angle					947:951	contact angle	939:951	contact angle of 130.0°	939:961	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	6	1	theme	first	1279:1283	arg1	cycle					1285:1289	the first cycle	1275:1289	the first cycle	1275:1289	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	4	2	dep	hydrophobicity	923:936	arg1	angle					947:951	contact angle	939:951	contact angle of 130.0°	939:961	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	3	3	theme	rapid	687:691	arg1	deposition					701:710	rapid in situ deposition	687:710	rapid in situ deposition of poly(methyl trichlorosilane) (PMTS)	687:749	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	6	4	theme	same	1258:1261	arg1	level					1263:1267	almost the same level	1247:1267	almost the same level as in the first cycle	1247:1289	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	5	5	theme	C-g-PEI-PMTS	1037:1048	arg1	aerogel					1026:1032	the composite aerogel	1012:1032	the composite aerogel of C-g-PEI-PMTS	1012:1048	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	5	5	theme	C-g-PEI-PMTS	1037:1048	arg1	Meanwhile					1001:1009	Meanwhile	1001:1009	Meanwhile	1001:1009	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	3	6	theme	in	693:694	arg1	deposition					701:710	rapid in situ deposition	687:710	rapid in situ deposition of poly(methyl trichlorosilane) (PMTS)	687:749	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	7	7	theme	trichloromethane-water	1337:1358	arg1	mixtures					1360:1367	the trichloromethane-water mixtures	1333:1367	the trichloromethane-water mixtures	1333:1367	The filtration separation efficiency for the trichloromethane-water mixtures remained at 99 % after 50 cycles, demonstrating encouraging reusability.					
37268071	7	8	theme	encouraging	1417:1427	arg1	reusability					1429:1439	encouraging reusability	1417:1439	encouraging reusability	1417:1439	The filtration separation efficiency for the trichloromethane-water mixtures remained at 99 % after 50 cycles, demonstrating encouraging reusability.					
37268071	8	9	theme	separation	1636:1645	arg1	fields					1616:1621	the fields	1612:1621	the fields of oil/water separation	1612:1645	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	8	10	theme	compressible	1517:1528	arg1	properties					1546:1555	highly compressible and hydrophobic properties	1510:1555	highly compressible and hydrophobic properties	1510:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	4	11	theme	ultralight	871:880	arg1	advantages					857:866	the advantages	853:866	the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %)	853:998	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	8	12	theme	oil/water	1626:1634	arg1	separation					1636:1645	oil/water separation	1626:1645	oil/water separation	1626:1645	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	13	theme	oxidized-NFC	585:596	arg1	use					578:580	the combined use	565:580	the combined use	565:580	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	1	14	theme	oil/water	292:300	arg1	separation					302:311	oil/water separation	292:311	oil/water separation	292:311	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	8	15	with	aerogel	1497:1503	arg1	properties					1546:1555	highly compressible and hydrophobic properties	1510:1555	highly compressible and hydrophobic properties	1510:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	16	theme	methyl	720:725	arg1	poly					715:718	poly	715:718	poly(methyl trichlorosilane) (PMTS)	715:749	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	16	theme	methyl	720:725	arg1	trichlorosilane					727:741	methyl trichlorosilane	720:741	methyl trichlorosilane	720:741	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	8	17	from	applications	1589:1600	arg1	fields					1616:1621	the fields	1612:1621	the fields of oil/water separation	1612:1645	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	18	theme	combined	569:576	arg1	use					578:580	the combined use	565:580	the combined use	565:580	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	2	19	theme	cellulose	410:418	arg1	aerogel					420:426	a hydrophobic nanofibrillated cellulose aerogel	380:426	a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation	380:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	4	20	theme	hydrophobicity	923:936	arg1	advantages					857:866	the advantages	853:866	the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %)	853:998	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	8	21	theme	hydrophobic	1534:1544	arg1	properties					1546:1555	highly compressible and hydrophobic properties	1510:1555	highly compressible and hydrophobic properties	1510:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	22	theme	aerogel	473:479	arg1	matrix					481:486	an aerogel matrix	470:486	an aerogel matrix of C-g-PEI with multiple cross-linked network structures	470:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	23	theme	poly	715:718	arg1	deposition					701:710	rapid in situ deposition	687:710	rapid in situ deposition of poly(methyl trichlorosilane) (PMTS)	687:749	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	6	24	theme	various	1226:1232	arg1	oils					1234:1237	various oils	1226:1237	various oils	1226:1237	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	1	25	theme	Nanofibrillated	104:118	arg1	aerogels					142:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	25	theme	Nanofibrillated	104:118	arg1	materials					173:181	ideal oil-sorbent materials	155:181	ideal oil-sorbent materials	155:181	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	26	theme	poor	192:195	arg1	stability					208:216	the poor structural stability	188:216	the poor structural stability	188:216	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	27	theme	separation	302:311	arg1	fields					282:287	the fields	278:287	the fields of oil/water separation	278:311	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	8	28	dep	strategy	1467:1474	arg1	prepare					1479:1485	prepare	1479:1485	to prepare NFC-based aerogel with highly compressible and hydrophobic properties	1476:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	2	29	theme	nanofibrillated	394:408	arg1	aerogel					420:426	a hydrophobic nanofibrillated cellulose aerogel	380:426	a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation	380:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	3	30	dep	in	693:694	arg1	situ					696:699	situ	696:699	situ	696:699	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	31	with	matrix	481:486	arg1	structures					534:543	multiple cross-linked network structures	504:543	multiple cross-linked network structures	504:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	6	32	theme	aerogel	1210:1216	arg1	capacity					1194:1201	the sorption capacity	1181:1201	the sorption capacity of the aerogel towards various oils	1181:1237	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	3	33	theme	C-g-PEI	491:497	arg1	matrix					481:486	an aerogel matrix	470:486	an aerogel matrix of C-g-PEI with multiple cross-linked network structures	470:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	4	34	theme	porosity	903:910	arg1	advantages					857:866	the advantages	853:866	the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %)	853:998	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	5	35	theme	composite	1016:1024	arg1	aerogel					1026:1032	the composite aerogel	1012:1032	the composite aerogel of C-g-PEI-PMTS	1012:1048	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	5	35	theme	composite	1016:1024	arg1	Meanwhile					1001:1009	Meanwhile	1001:1009	Meanwhile	1001:1009	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	2	36	theme	present	321:327	arg1	work					329:332	the present work	317:332	the present work	317:332	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	1	37	theme	ideal	155:159	arg1	aerogels					142:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	37	theme	ideal	155:159	arg1	materials					173:181	ideal oil-sorbent materials	155:181	ideal oil-sorbent materials	155:181	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	0	38	theme	cellulose	52:60	arg1	aerogels					62:69	cellulose aerogels	52:69	cellulose aerogels	52:69	Highly compressible and hydrophobic nanofibrillated cellulose aerogels for cyclic oil/water separation.					
37268071	2	39	theme	facile	347:352	arg1	strategy					354:361	a facile strategy	345:361	a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation	345:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	4	40	theme	ONC-based	811:819	arg1	C-g-PEI-PMTS					830:841	C-g-PEI-PMTS	830:841	C-g-PEI-PMTS	830:841	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	4	40	theme	ONC-based	811:819	arg1	aerogel					821:827	The resulting ONC-based aerogel	797:827	The resulting ONC-based aerogel (C-g-PEI-PMTS)	797:842	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	1	41	theme	structural	197:206	arg1	stability					208:216	the poor structural stability	188:216	the poor structural stability	188:216	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	2	42	theme	oil/water	439:447	arg1	separation					449:458	cyclic oil/water separation	432:458	cyclic oil/water separation	432:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	5	43	theme	simple	1105:1110	arg1	method					1133:1138	a simple mechanical squeezing method	1103:1138	a simple mechanical squeezing method	1103:1138	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	3	44	theme	diglycidyl	650:659	arg1	EGDE					668:671	EGDE	668:671	EGDE	668:671	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	44	theme	diglycidyl	650:659	arg1	ether					661:665	ethylene glycol diglycidyl ether	634:665	ethylene glycol diglycidyl ether (EGDE)	634:672	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	4	45	theme	resulting	801:809	arg1	C-g-PEI-PMTS					830:841	C-g-PEI-PMTS	830:841	C-g-PEI-PMTS	830:841	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	4	45	theme	resulting	801:809	arg1	aerogel					821:827	The resulting ONC-based aerogel	797:827	The resulting ONC-based aerogel (C-g-PEI-PMTS)	797:842	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	2	46	theme	cyclic	432:437	arg1	separation					449:458	cyclic oil/water separation	432:458	cyclic oil/water separation	432:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	4	47	theme	elasticity	979:988	arg1	advantages					857:866	the advantages	853:866	the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %)	853:998	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	3	48	theme	low-temperature	761:775	arg1	reaction					787:794	a low-temperature gas-solid reaction	759:794	a low-temperature gas-solid reaction	759:794	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	1	49	from	applications	262:273	arg1	fields					282:287	the fields	278:287	the fields of oil/water separation	278:311	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	3	50	theme	ether	661:665	arg1	use					578:580	the combined use	565:580	the combined use	565:580	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	51	theme	polyethyleneimine	605:621	arg1	use					578:580	the combined use	565:580	the combined use	565:580	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	8	52	theme	NFC-based	1487:1495	arg1	aerogel					1497:1503	NFC-based aerogel	1487:1503	NFC-based aerogel with highly compressible and hydrophobic properties	1487:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	53	theme	network	526:532	arg1	structures					534:543	multiple cross-linked network structures	504:543	multiple cross-linked network structures	504:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	4	54	theme	remarkable	968:977	arg1	elasticity					979:988	remarkable elasticity	968:988	remarkable elasticity (95.86 %)	968:998	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	4	54	theme	remarkable	968:977	arg1	%					997:997	95.86 %	991:997	95.86 %	991:997	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	5	55	theme	squeezing	1123:1131	arg1	method					1133:1138	a simple mechanical squeezing method	1103:1138	a simple mechanical squeezing method	1103:1138	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	3	56	link	cross-linked	513:524	arg1	structures					534:543	multiple cross-linked network structures	504:543	multiple cross-linked network structures	504:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	8	57	theme	efficient	1457:1465	arg1	strategy					1467:1474	an efficient strategy	1454:1474	an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties	1454:1555	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	4	58	theme	contact	939:945	arg1	angle					947:951	contact angle	939:951	contact angle of 130.0°	939:961	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	1	59	theme	-based	135:140	arg1	aerogels					142:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	59	theme	-based	135:140	arg1	materials					173:181	ideal oil-sorbent materials	155:181	ideal oil-sorbent materials	155:181	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	6	60	from	level	1263:1267	arg1	cycle					1285:1289	the first cycle	1275:1289	the first cycle	1275:1289	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	4	61	theme	high	898:901	arg1	porosity					903:910	high porosity	898:910	high porosity (95.73 %)	898:920	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	4	61	theme	high	898:901	arg1	%					919:919	95.73 %	913:919	95.73 %	913:919	The resulting ONC-based aerogel (C-g-PEI-PMTS) exhibits the advantages of ultralight (53.80 mg/cm3), high porosity (95.73 %), hydrophobicity (contact angle of 130.0°) and remarkable elasticity (95.86 %).					
37268071	6	62	theme	sorption	1185:1192	arg1	capacity					1194:1201	the sorption capacity	1181:1201	the sorption capacity of the aerogel towards various oils	1181:1237	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	3	63	theme	ethylene	634:641	arg1	EGDE					668:671	EGDE	668:671	EGDE	668:671	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	63	theme	ethylene	634:641	arg1	ether					661:665	ethylene glycol diglycidyl ether	634:665	ethylene glycol diglycidyl ether (EGDE)	634:672	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	64	theme	multiple	504:511	arg1	structures					534:543	multiple cross-linked network structures	504:543	multiple cross-linked network structures	504:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	8	65	theme	NFC	1605:1607	arg1	applications					1589:1600	the applications	1585:1600	the applications of NFC in the fields of oil/water separation	1585:1645	In summary, an efficient strategy to prepare NFC-based aerogel with highly compressible and hydrophobic properties is developed, which expands the applications of NFC in the fields of oil/water separation.					
37268071	3	66	theme	glycol	643:648	arg1	EGDE					668:671	EGDE	668:671	EGDE	668:671	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	66	theme	glycol	643:648	arg1	ether					661:665	ethylene glycol diglycidyl ether	634:665	ethylene glycol diglycidyl ether (EGDE)	634:672	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	3	67	theme	cross-linked	513:524	arg1	structures					534:543	multiple cross-linked network structures	504:543	multiple cross-linked network structures	504:543	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	1	68	theme	practical	252:260	arg1	applications					262:273	their practical applications	246:273	their practical applications in the fields of oil/water separation	246:311	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	0	69	theme	oil/water	82:90	arg1	separation					92:101	cyclic oil/water separation	75:101	cyclic oil/water separation	75:101	Highly compressible and hydrophobic nanofibrillated cellulose aerogels for cyclic oil/water separation.					
37268071	7	70	theme	separation	1307:1316	arg1	efficiency					1318:1327	The filtration separation efficiency	1292:1327	The filtration separation efficiency for the trichloromethane-water mixtures	1292:1367	The filtration separation efficiency for the trichloromethane-water mixtures remained at 99 % after 50 cycles, demonstrating encouraging reusability.					
37268071	2	71	theme	hydrophobic	382:392	arg1	aerogel					420:426	a hydrophobic nanofibrillated cellulose aerogel	380:426	a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation	380:458	In the present work, we report a facile strategy for constructing a hydrophobic nanofibrillated cellulose aerogel for cyclic oil/water separation.					
37268071	7	72	theme	filtration	1296:1305	arg1	efficiency					1318:1327	The filtration separation efficiency	1292:1327	The filtration separation efficiency for the trichloromethane-water mixtures	1292:1367	The filtration separation efficiency for the trichloromethane-water mixtures remained at 99 % after 50 cycles, demonstrating encouraging reusability.					
37268071	3	73	theme	gas-solid	777:785	arg1	reaction					787:794	a low-temperature gas-solid reaction	759:794	a low-temperature gas-solid reaction	759:794	Briefly, an aerogel matrix of C-g-PEI with multiple cross-linked network structures was constructed via the combined use of oxidized-NFC (ONC), polyethyleneimine (PEI), and ethylene glycol diglycidyl ether (EGDE), followed by rapid in situ deposition of poly(methyl trichlorosilane) (PMTS) through a low-temperature gas-solid reaction.					
37268071	0	74	theme	cyclic	75:80	arg1	separation					92:101	cyclic oil/water separation	75:101	cyclic oil/water separation	75:101	Highly compressible and hydrophobic nanofibrillated cellulose aerogels for cyclic oil/water separation.					
37268071	5	75	theme	oil	1076:1078	arg1	sorption-desorption					1080:1098	oil sorption-desorption	1076:1098	oil sorption-desorption by a simple mechanical squeezing method	1076:1138	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
37268071	6	76	theme	sorption-desorption	1160:1178	arg1	10 cycles					1147:1155	10 cycles	1147:1155	10 cycles of sorption-desorption	1147:1178	After 10 cycles of sorption-desorption, the sorption capacity of the aerogel towards various oils reached almost the same level as in the first cycle.					
37268071	1	77	theme	oil-sorbent	161:171	arg1	aerogels					142:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels	104:149	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	1	77	theme	oil-sorbent	161:171	arg1	materials					173:181	ideal oil-sorbent materials	155:181	ideal oil-sorbent materials	155:181	Nanofibrillated cellulose (NFC)-based aerogels are ideal oil-sorbent materials, but the poor structural stability and hydrophilicity restrain their practical applications in the fields of oil/water separation.					
37268071	5	78	theme	mechanical	1112:1121	arg1	method					1133:1138	a simple mechanical squeezing method	1103:1138	a simple mechanical squeezing method	1103:1138	Meanwhile, the composite aerogel of C-g-PEI-PMTS is extremely suitable for oil sorption-desorption by a simple mechanical squeezing method.					
36364069	9	0	theme	biopolymeric	1388:1399	arg1	composites					1401:1410	biopolymeric composites	1388:1410	biopolymeric composites	1388:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	4	1	theme	starting	649:656	arg1	point					658:662	a good starting point	642:662	a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides	642:743	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
36364069	6	2	theme	lignosulfonamide	966:981	arg1	structure					935:943	the lignin structure	924:943	the lignin structure	924:943	Spectroscopic measurements confirmed the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide.					
36364069	6	2	theme	lignosulfonamide	966:981	arg1	formation					953:961	the formation	949:961	the formation of lignosulfonamide	949:981	Spectroscopic measurements confirmed the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide.					
36364069	3	3	theme	modification	516:527	arg1	procedure					529:537	a two-step modification procedure	505:537	a two-step modification procedure	505:537	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	2	4	theme	pulping	297:303	arg1	industries					305:314	the paper and wood pulping industries	278:314	industries	305:314	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	6	5	theme	Spectroscopic	848:860	arg1	measurements					862:873	Spectroscopic measurements	848:873	Spectroscopic measurements	848:873	Spectroscopic measurements confirmed the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide.					
36364069	7	6	theme	visible	1154:1160	arg1	surface					1146:1152	the surface	1142:1152	the surface visible on the SEM imaging	1142:1179	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	4	7	theme	knowledge	687:695	arg1	state					678:682	the state	674:682	the state of knowledge	674:695	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
36364069	4	8	theme	lignosulfonamides	727:743	arg1	properties					713:722	the properties	709:722	the properties of lignosulfonamides	709:743	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
36364069	1	9	theme	occurring	175:183	arg1	polymers					193:200	the most commonly occurring natural polymers	157:200	the most commonly occurring natural polymers	157:200	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	7	10	theme	minute	1110:1115	arg1	changes					1131:1137	only minute morphological changes	1105:1137	only minute morphological changes of the surface visible on the SEM imaging	1105:1179	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	3	11	theme	lignin	495:500	arg1	derivatives					480:490	sulfonamide derivatives	468:490	sulfonamide derivatives of lignin	468:500	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	9	12	theme	new	1425:1427	arg1	class					1429:1433	a new class	1423:1433	a new class of functional, value-added, sustainable additives	1423:1483	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	9	13	with	derivatives	1332:1342	arg1	application					1361:1371	a potential application	1349:1371	a potential application as a filler in biopolymeric composites	1349:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	1	14	theme	aromatic	87:94	arg1	macromolecule					96:108	a highly aromatic macromolecule	78:108	a highly aromatic macromolecule building plant cells	78:129	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	1	14	theme	aromatic	87:94	arg1	polymers					193:200	the most commonly occurring natural polymers	157:200	the most commonly occurring natural polymers	157:200	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	1	14	theme	aromatic	87:94	arg1	two					150:152	two	150:152	two	150:152	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	2	15	theme	method	355:360	arg1	result					319:324	a result	317:324	a result of the used lignin isolation method	317:360	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	2	15	theme	method	355:360	arg1	paper					282:286	the paper and wood pulping industries	278:314	paper	282:286	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	7	16	theme	surface	1146:1152	arg1	changes					1131:1137	only minute morphological changes	1105:1137	only minute morphological changes of the surface visible on the SEM imaging	1105:1179	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	9	17	theme	As-prepared	1301:1311	arg1	derivatives					1332:1342	As-prepared sulfonamide lignin derivatives	1301:1342	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites	1301:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	9	18	theme	potential	1351:1359	arg1	application					1361:1371	a potential application	1349:1371	a potential application as a filler in biopolymeric composites	1349:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	2	19	theme	wood	292:295	arg1	industries					305:314	the paper and wood pulping industries	278:314	industries	305:314	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	8	20	theme	improved	1227:1234	arg1	parameters					1236:1245	improved parameters	1227:1245	improved parameters of thermal stability in relation to the raw material	1227:1298	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	2	21	theme	isolation	345:353	arg1	method					355:360	the used lignin isolation method	329:360	the used lignin isolation method	329:360	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	9	22	theme	sulfonamide	1313:1323	arg1	derivatives					1332:1342	As-prepared sulfonamide lignin derivatives	1301:1342	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites	1301:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	3	23	used	used	425:428	arg2	lignosulfonate					407:420	sodium lignosulfonate	400:420	sodium lignosulfonate	400:420	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	3	23	used	used	425:428	arg2	material					444:451	a starting material	433:451	a starting material	433:451	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	1	24	theme	polymers	193:200	arg1	two					150:152	two	150:152	two	150:152	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	1	24	theme	polymers	193:200	arg1	polymers					193:200	the most commonly occurring natural polymers	157:200	the most commonly occurring natural polymers	157:200	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	1	24	theme	polymers	193:200	arg1	macromolecule					96:108	a highly aromatic macromolecule	78:108	a highly aromatic macromolecule building plant cells	78:129	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	9	25	theme	lignin	1325:1330	arg1	derivatives					1332:1342	As-prepared sulfonamide lignin derivatives	1301:1342	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites	1301:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	7	26	theme	modification	1050:1061	arg1	procedure					1063:1071	the modification procedure	1046:1071	the modification procedure	1046:1071	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	1	27	theme	plant	119:123	arg1	cells					125:129	plant cells	119:129	plant cells	119:129	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	2	28	theme	lignin	338:343	arg1	method					355:360	the used lignin isolation method	329:360	the used lignin isolation method	329:360	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	0	29	theme	Stable	44:49	arg1	Lignosulfonamides					51:67	Thermally Stable Lignosulfonamides	34:67	Thermally Stable Lignosulfonamides	34:67	Synthesis and Characterization of Thermally Stable Lignosulfonamides.					
36364069	6	30	theme	lignin	928:933	arg1	structure					935:943	the lignin structure	924:943	the lignin structure	924:943	Spectroscopic measurements confirmed the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide.					
36364069	9	31	theme	additives	1475:1483	arg1	class					1429:1433	a new class	1423:1433	a new class of functional, value-added, sustainable additives	1423:1483	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	2	32	theme	sulfite	369:375	arg1	process					377:383	sulfite process	369:383	sulfite process	369:383	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	2	33	theme	technical	232:240	arg1	lignin					242:247	technical lignin	232:247	technical lignin	232:247	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	1	34	theme	natural	185:191	arg1	polymers					193:200	the most commonly occurring natural polymers	157:200	the most commonly occurring natural polymers	157:200	Lignin, a highly aromatic macromolecule building plant cells, and cellulose are two of the most commonly occurring natural polymers.					
36364069	3	35	theme	sodium	400:405	arg1	lignosulfonate					407:420	sodium lignosulfonate	400:420	sodium lignosulfonate	400:420	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	3	35	theme	sodium	400:405	arg1	material					444:451	a starting material	433:451	a starting material	433:451	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	4	36	theme	good	644:647	arg1	point					658:662	a good starting point	642:662	a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides	642:743	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
36364069	7	37	theme	morphological	1117:1129	arg1	changes					1131:1137	only minute morphological changes	1105:1137	only minute morphological changes of the surface visible on the SEM imaging	1105:1179	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	8	38	theme	thermal	1250:1256	arg1	stability					1258:1266	thermal stability	1250:1266	thermal stability	1250:1266	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	8	39	theme	obtained	1186:1193	arg1	materials					1195:1203	The obtained materials	1182:1203	The obtained materials	1182:1203	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	9	40	from	filler	1378:1383	arg1	composites					1401:1410	biopolymeric composites	1388:1410	biopolymeric composites	1388:1410	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	3	41	theme	starting	435:442	arg1	lignosulfonate					407:420	sodium lignosulfonate	400:420	sodium lignosulfonate	400:420	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	3	41	theme	starting	435:442	arg1	material					444:451	a starting material	433:451	a starting material	433:451	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	0	42	theme	Lignosulfonamides	51:67	arg1	Characterization					14:29	Characterization	14:29	Characterization	14:29	Synthesis and Characterization of Thermally Stable Lignosulfonamides.					
36364069	0	42	theme	Lignosulfonamides	51:67	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and Characterization of Thermally Stable Lignosulfonamides.					
36364069	6	43	theme	dihexylamine	906:917	arg1	incorporation					889:901	the incorporation	885:901	the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide	885:981	Spectroscopic measurements confirmed the incorporation of dihexylamine into the lignin structure and the formation of lignosulfonamide.					
36364069	2	44	dep	process	377:383	arg1	i.e.					363:366	i.e.	363:366	i.e.	363:366	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	7	45	theme	SEM	1169:1171	arg1	imaging					1173:1179	the SEM imaging	1165:1179	the SEM imaging	1165:1179	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	8	46	theme	stability	1258:1266	arg1	parameters					1236:1245	improved parameters	1227:1245	improved parameters of thermal stability in relation to the raw material	1227:1298	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	2	47	from	by-product	264:273	arg1	industries					305:314	the paper and wood pulping industries	278:314	industries	305:314	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	2	47	from	by-product	264:273	arg1	result					319:324	a result	317:324	a result of the used lignin isolation method	317:360	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	2	47	from	by-product	264:273	arg1	paper					282:286	the paper and wood pulping industries	278:314	paper	282:286	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	7	48	theme	crystalline	988:998	arg1	structure					1000:1008	The crystalline structure	984:1008	The crystalline structure of the material	984:1024	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	3	49	theme	two-step	507:514	arg1	procedure					529:537	a two-step modification procedure	505:537	a two-step modification procedure	505:537	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	4	50	theme	lignin	568:573	arg1	modification					575:586	the lignin modification	564:586	the lignin modification	564:586	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
36364069	7	51	theme	material	1017:1024	arg1	structure					1000:1008	The crystalline structure	984:1008	The crystalline structure of the material	984:1024	The crystalline structure of the material was not affected by the modification procedure, as evidenced by the WAXD, with only minute morphological changes of the surface visible on the SEM imaging.					
36364069	8	52	theme	raw	1287:1289	arg1	material					1291:1298	the raw material	1283:1298	the raw material	1283:1298	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	9	53	dep	functional	1438:1447	arg1	sustainable					1463:1473	sustainable	1463:1473	sustainable	1463:1473	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	9	53	dep	functional	1438:1447	arg1	value-added					1450:1460	value-added	1450:1460	value-added	1450:1460	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	9	54	theme	functional	1438:1447	arg1	additives					1475:1483	functional, value-added, sustainable additives	1438:1483	functional, value-added, sustainable additives	1438:1483	As-prepared sulfonamide lignin derivatives with a potential application as a filler in biopolymeric composites may become a new class of functional, value-added, sustainable additives.					
36364069	3	55	theme	sulfonamide	468:478	arg1	derivatives					480:490	sulfonamide derivatives	468:490	sulfonamide derivatives of lignin	468:500	In this work, sodium lignosulfonate is used as a starting material to manufacture sulfonamide derivatives of lignin in a two-step modification procedure.					
36364069	2	56	theme	lignin	242:247	arg1	Lignosulfonate					203:216	Lignosulfonate	203:216	Lignosulfonate	203:216	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	2	56	theme	lignin	242:247	arg1	grade					223:227	a grade	221:227	a grade	221:227	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	8	57	from	parameters	1236:1245	arg1	relation					1271:1278	relation	1271:1278	relation to the raw material	1271:1298	The obtained materials were characterized by improved parameters of thermal stability in relation to the raw material.					
36364069	2	58	theme	used	333:336	arg1	method					355:360	the used lignin isolation method	329:360	the used lignin isolation method	329:360	Lignosulfonate is a grade of technical lignin, obtained as a by-product in the paper and wood pulping industries, a result of the used lignin isolation method, i.e., sulfite process.					
36364069	4	59	theme	modification	575:586	arg1	direction					551:559	this direction	546:559	this direction of the lignin modification	546:586	Since this direction of the lignin modification is rather rarely investigated and discussed, it makes a good starting point to expand the state of knowledge and explore the properties of lignosulfonamides.					
37015281	0	0	theme	chemical-mechanical	75:93	arg1	treatment					95:103	a chemical-mechanical treatment	73:103	a chemical-mechanical treatment under mild conditions	73:125	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	4	1	theme	fiber	940:944	arg1	diameter					946:953	fiber diameter	940:953	fiber diameter from 16.56 to 5.48 μm	940:975	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	1	2	from	available	175:183	arg1	quantities					194:203	large quantities	188:203	large quantities	188:203	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	3	theme	corn	163:166	arg1	cob					168:170	corn cob	163:170	corn cob	163:170	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	4	4	theme	morphological	758:770	arg1	variation					772:780	the morphological variation	754:780	the morphological variation	754:780	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	7	5	theme	low	1515:1517	arg1	cost					1519:1522	a relatively low cost	1502:1522	a relatively low cost	1502:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	7	6	theme	conventional	1437:1448	arg1	blender					1461:1467	a conventional high-speed blender	1435:1467	a conventional high-speed blender in a mild condition process with a relatively low cost	1435:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	6	7	theme	NCC	1254:1256	arg1	characteristic					1236:1249	this characteristic	1231:1249	this characteristic of NCC	1231:1256	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	3	8	theme	high	629:632	arg1	yields					634:639	yields	634:639	yields	634:639	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	1	9	theme	various	248:254	arg1	applications					256:267	various applications	248:267	various applications	248:267	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	2	10	theme	conventional	498:509	arg1	blender					522:528	a conventional high-speed blender	496:528	a conventional high-speed blender	496:528	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	7	11	with	pathway	1550:1556	arg1	cost					1519:1522	a relatively low cost	1502:1522	a relatively low cost	1502:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	6	12	theme	various	1316:1322	arg1	fields					1324:1329	various fields	1316:1329	various fields of polymer composites	1316:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	4	13	from	fiber	838:842	arg1	dimension					786:794	dimension	786:794	dimension	786:794	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	13	from	fiber	838:842	arg1	variation					772:780	the morphological variation	754:780	the morphological variation	754:780	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	7	14	from	blender	1461:1467	arg1	process					1489:1495	a mild condition process	1472:1495	a mild condition process	1472:1495	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	4	15	theme	electron	718:725	arg1	SEM					739:741	SEM	739:741	SEM	739:741	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	15	theme	electron	718:725	arg1	microscopy					727:736	Scanning electron microscopy	709:736	Scanning electron microscopy (SEM)	709:742	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	7	16	attach	isolating	1396:1404	arg2	method					1385:1390	a method	1383:1390	a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved	1383:1597	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	7	16	attach	isolating	1396:1404	arg1	waste					1423:1427	corncob waste	1415:1427	corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield	1415:1572	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	7	17	theme	corncob	1415:1421	arg1	waste					1423:1427	corncob waste	1415:1427	corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield	1415:1572	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	6	18	from	agent	1307:1311	arg1	fields					1324:1329	various fields	1316:1329	various fields of polymer composites	1316:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	7	19	with	yield	1568:1572	arg1	cost					1519:1522	a relatively low cost	1502:1522	a relatively low cost	1502:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	4	20	dep	5.48 μm	969:975	arg1	to					966:967	to	966:967	to	966:967	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	2	21	theme	low	381:383	arg1	50 °C					398:402	50 °C	398:402	50 °C	398:402	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	21	theme	low	381:383	arg1	temperature					385:395	low temperature	381:395	low temperature (50 °C)	381:403	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	0	22	theme	mild	111:114	arg1	conditions					116:125	mild conditions	111:125	mild conditions	111:125	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	5	23	theme	fiber	1064:1068	arg1	diameters					1070:1078	fiber diameters	1064:1078	fiber diameters ranging between 9.35 nm and 6.51 nm	1064:1114	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	7	24	from	yield	1568:1572	arg1	process					1489:1495	a mild condition process	1472:1495	a mild condition process	1472:1495	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	2	25	theme	shorter	422:428	arg1	extraction					435:444	a relatively shorter time extraction	409:444	a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender	409:528	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	25	theme	shorter	422:428	arg1	30 min					447:452	30 min	447:452	30 min	447:452	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	0	26	theme	yield	5:9	arg1	production					11:20	High yield production	0:20	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.	0:126	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	4	27	from	5.48 μm	969:975	arg1	decrease					928:935	a decrease	926:935	a decrease in fiber diameter from 16.56 to 5.48 μm	926:975	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	27	from	5.48 μm	969:975	arg1	diameter					946:953	fiber diameter	940:953	fiber diameter from 16.56 to 5.48 μm	940:975	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	6	28	contain	has	1258:1260	arg2	potential					1266:1274	the potential to be applied as a reinforcing agent in various fields of polymer composites	1262:1351	the potential to be applied as a reinforcing agent in various fields of polymer composites	1262:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	6	28	contain	has	1258:1260	arg1	characteristic					1236:1249	this characteristic	1231:1249	this characteristic of NCC	1231:1256	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	0	29	theme	High	0:3	arg1	production					11:20	High yield production	0:20	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.	0:126	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	4	30	theme	delignification	822:836	arg1	DF					845:846	DF	845:846	DF	845:846	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	30	theme	delignification	822:836	arg1	fiber					838:842	delignification fiber	822:842	delignification fiber (DF)	822:847	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	5	31	theme	microscopy	1000:1009	arg1	images					1017:1022	Transmission electron microscopy (TEM) images	978:1022	Transmission electron microscopy (TEM) images	978:1022	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	1	32	theme	large	188:192	arg1	quantities					194:203	large quantities	188:203	large quantities	188:203	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	4	33	from	cellulose	850:858	arg1	dimension					786:794	dimension	786:794	dimension	786:794	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	33	from	cellulose	850:858	arg1	variation					772:780	the morphological variation	754:780	the morphological variation	754:780	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	6	34	theme	high	1174:1177	arg1	stability					1187:1195	relatively high thermal stability	1163:1195	relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites	1163:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	5	35	theme	nano-scale	1038:1047	arg1	dimension					1049:1057	the nano-scale dimension	1034:1057	the nano-scale dimension	1034:1057	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	5	36	theme	electron	991:998	arg1	TEM					1012:1014	TEM	1012:1014	TEM	1012:1014	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	5	36	theme	electron	991:998	arg1	microscopy					1000:1009	Transmission electron microscopy	978:1009	Transmission electron microscopy (TEM) images	978:1022	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	2	37	theme	nanocrystalline	298:312	arg1	cellulose					314:322	nanocrystalline cellulose	298:322	nanocrystalline cellulose	298:322	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	6	38	dep	437 °C.	1217:1223	arg1	has					1258:1260	has	1258:1260	has the potential to be applied as a reinforcing agent in various fields of polymer composites	1258:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	6	39	theme	Thermogravimetric	1117:1133	arg1	analysis					1135:1142	Thermogravimetric analysis	1117:1142	Thermogravimetric analysis	1117:1142	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	4	40	from	fiber	810:814	arg1	dimension					786:794	dimension	786:794	dimension	786:794	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	40	from	fiber	810:814	arg1	variation					772:780	the morphological variation	754:780	the morphological variation	754:780	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	3	41	from	cobs	576:579	arg1	NCC					531:533	NCC	531:533	NCC from cellulose	531:548	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	3	41	from	cobs	576:579	arg1	α-cellulose					554:564	α-cellulose	554:564	α-cellulose from corn cobs	554:579	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	0	42	theme	cellulose	41:49	arg1	production					11:20	High yield production	0:20	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.	0:126	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	2	43	theme	sulfuric	338:345	arg1	 w/v					372:375	30 % w/v	368:375	30 % w/v	368:375	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	43	theme	sulfuric	338:345	arg1	concentrations					352:365	mild sulfuric acid concentrations	333:365	mild sulfuric acid concentrations (30 % w/v)	333:376	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	7	44	theme	condition	1479:1487	arg1	process					1489:1495	a mild condition process	1472:1495	a mild condition process	1472:1495	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	0	45	theme	nanocrystalline	25:39	arg1	cellulose					41:49	nanocrystalline cellulose	25:49	nanocrystalline cellulose	25:49	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	7	46	theme	high	1563:1566	arg1	yield					1568:1572	high yield	1563:1572	high yield	1563:1572	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	2	47	theme	high-speed	511:520	arg1	blender					522:528	a conventional high-speed blender	496:528	a conventional high-speed blender	496:528	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	7	48	theme	mild	1474:1477	arg1	process					1489:1495	a mild condition process	1472:1495	a mild condition process	1472:1495	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	4	49	theme	cob	806:808	arg1	fiber					810:814	corn cob fiber	801:814	corn cob fiber (CF)	801:819	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	49	theme	cob	806:808	arg1	CF					817:818	CF	817:818	CF	817:818	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	0	50	theme	corn	56:59	arg1	cob					61:63	corn cob	56:63	corn cob	56:63	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	4	51	theme	pretreatment	900:911	arg1	stage					913:917	each pretreatment stage	895:917	each pretreatment stage	895:917	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	0	52	from	cob	61:63	arg1	production					11:20	High yield production	0:20	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.	0:126	High yield production of nanocrystalline cellulose from corn cob through a chemical-mechanical treatment under mild conditions.					
37015281	5	53	theme	Transmission	978:989	arg1	TEM					1012:1014	TEM	1012:1014	TEM	1012:1014	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	5	53	theme	Transmission	978:989	arg1	microscopy					1000:1009	Transmission electron microscopy	978:1009	Transmission electron microscopy (TEM) images	978:1022	Transmission electron microscopy (TEM) images confirmed the nano-scale dimension with fiber diameters ranging between 9.35 nm and 6.51 nm.					
37015281	2	54	theme	acid	347:350	arg1	 w/v					372:375	30 % w/v	368:375	30 % w/v	368:375	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	54	theme	acid	347:350	arg1	concentrations					352:365	mild sulfuric acid concentrations	333:365	mild sulfuric acid concentrations (30 % w/v)	333:376	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	55	theme	time	430:433	arg1	extraction					435:444	a relatively shorter time extraction	409:444	a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender	409:528	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	55	theme	time	430:433	arg1	30 min					447:452	30 min	447:452	30 min	447:452	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	6	56	theme	reinforcing	1295:1305	arg1	agent					1307:1311	a reinforcing agent	1293:1311	a reinforcing agent in various fields of polymer composites	1293:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	4	57	from	α-cellulose	865:875	arg1	dimension					786:794	dimension	786:794	dimension	786:794	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	57	from	α-cellulose	865:875	arg1	variation					772:780	the morphological variation	754:780	the morphological variation	754:780	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	3	58	theme	corn	571:574	arg1	cobs					576:579	corn cobs	571:579	corn cobs	571:579	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	1	59	from	quantities	194:203	arg1	available					175:183	available	175:183	available	175:183	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	60	theme	Agricultural	128:139	arg1	waste					149:153	Agricultural biomass waste	128:153	Agricultural biomass waste such as corn cob	128:170	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	60	theme	Agricultural	128:139	arg1	materials					234:242	renewable materials	224:242	renewable materials for various applications	224:267	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	4	61	from	decrease	928:935	arg1	diameter					946:953	fiber diameter	940:953	fiber diameter from 16.56 to 5.48 μm	940:975	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	61	from	decrease	928:935	arg1	5.48 μm					969:975	5.48 μm	969:975	5.48 μm	969:975	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	6	62	theme	polymer	1334:1340	arg1	composites					1342:1351	polymer composites	1334:1351	polymer composites	1334:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	3	63	theme	%	676:676	arg1	yields					634:639	yields	634:639	yields	634:639	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	3	63	theme	%	676:676	arg1	crystallinities					645:659	crystallinities	645:659	crystallinities	645:659	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	7	64	with	blender	1461:1467	arg1	cost					1519:1522	a relatively low cost	1502:1522	a relatively low cost	1502:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	1	65	theme	biomass	141:147	arg1	waste					149:153	Agricultural biomass waste	128:153	Agricultural biomass waste such as corn cob	128:170	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	65	theme	biomass	141:147	arg1	materials					234:242	renewable materials	224:242	renewable materials for various applications	224:267	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	3	66	from	cellulose	540:548	arg1	NCC					531:533	NCC	531:533	NCC from cellulose	531:548	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	3	66	from	cellulose	540:548	arg1	α-cellulose					554:564	α-cellulose	554:564	α-cellulose from corn cobs	554:579	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	7	67	theme	friendly	1541:1548	arg1	pathway					1550:1556	environmentally friendly pathway	1525:1556	environmentally friendly pathway	1525:1556	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	2	68	theme	Corn	270:273	arg1	cob					275:277	Corn cob	270:277	Corn cob	270:277	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	7	69	theme	high-speed	1450:1459	arg1	blender					1461:1467	a conventional high-speed blender	1435:1467	a conventional high-speed blender in a mild condition process with a relatively low cost	1435:1522	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	6	70	theme	thermal	1179:1185	arg1	stability					1187:1195	relatively high thermal stability	1163:1195	relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites	1163:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	4	71	theme	Scanning	709:716	arg1	SEM					739:741	SEM	739:741	SEM	739:741	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	71	theme	Scanning	709:716	arg1	microscopy					727:736	Scanning electron microscopy	709:736	Scanning electron microscopy (SEM)	709:742	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	2	72	theme	mild	333:336	arg1	 w/v					372:375	30 % w/v	368:375	30 % w/v	368:375	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	72	theme	mild	333:336	arg1	concentrations					352:365	mild sulfuric acid concentrations	333:365	mild sulfuric acid concentrations (30 % w/v)	333:376	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	73	theme	mechanical	469:478	arg1	treatment					480:488	mechanical treatment	469:488	mechanical treatment using a conventional high-speed blender	469:528	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	1	74	used	used	216:219	arg2	materials					234:242	renewable materials	224:242	renewable materials for various applications	224:267	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	74	used	used	216:219	arg2	waste					149:153	Agricultural biomass waste	128:153	Agricultural biomass waste such as corn cob	128:170	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	4	75	theme	corn	801:804	arg1	fiber					810:814	corn cob fiber	801:814	corn cob fiber (CF)	801:819	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	4	75	theme	corn	801:804	arg1	CF					817:818	CF	817:818	CF	817:818	Scanning electron microscopy (SEM) evaluated the morphological variation and dimension from corn cob fiber (CF), delignification fiber (DF), cellulose, and α-cellulose, which shows that each pretreatment stage causes a decrease in fiber diameter from 16.56 to 5.48 μm.					
37015281	2	76	theme	%	371:371	arg1	 w/v					372:375	30 % w/v	368:375	30 % w/v	368:375	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	76	theme	%	371:371	arg1	concentrations					352:365	mild sulfuric acid concentrations	333:365	mild sulfuric acid concentrations (30 % w/v)	333:376	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	7	77	from	pathway	1550:1556	arg1	process					1489:1495	a mild condition process	1472:1495	a mild condition process	1472:1495	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	1	78	theme	renewable	224:232	arg1	materials					234:242	renewable materials	224:242	renewable materials for various applications	224:267	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	1	78	theme	renewable	224:232	arg1	waste					149:153	Agricultural biomass waste	128:153	Agricultural biomass waste such as corn cob	128:170	Agricultural biomass waste such as corn cob is available in large quantities and can be used as renewable materials for various applications.					
37015281	6	79	theme	composites	1342:1351	arg1	fields					1324:1329	various fields	1316:1329	various fields of polymer composites	1316:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	3	80	theme	%	692:692	arg1	yields					634:639	yields	634:639	yields	634:639	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	3	80	theme	%	692:692	arg1	crystallinities					645:659	crystallinities	645:659	crystallinities	645:659	NCC from cellulose and α-cellulose from corn cobs have been successfully isolated with relatively high yields and crystallinities of 50.07-65.33 % and 65.5-69.9 %, respectively.					
37015281	7	81	theme	environmentally	1525:1539	arg1	pathway					1550:1556	environmentally friendly pathway	1525:1556	environmentally friendly pathway	1525:1556	Finally, this study presents a method for isolating NCC from corncob waste using a conventional high-speed blender in a mild condition process with a relatively low cost, environmentally friendly pathway, and high yield that was still preserved.					
37015281	2	82	theme	30 	368:370	arg1	 w/v					372:375	30 % w/v	368:375	30 % w/v	368:375	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	2	82	theme	30 	368:370	arg1	concentrations					352:365	mild sulfuric acid concentrations	333:365	mild sulfuric acid concentrations (30 % w/v)	333:376	Corn cob was converted into nanocrystalline cellulose by using mild sulfuric acid concentrations (30 % w/v) at low temperature (50 °C) and a relatively shorter time extraction (30 min) combined with mechanical treatment using a conventional high-speed blender.					
37015281	6	83	contain	has	1159:1161	arg2	stability					1187:1195	relatively high thermal stability	1163:1195	relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites	1163:1351	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
37015281	6	83	contain	has	1159:1161	arg1	NCC					1155:1157	NCC	1155:1157	NCC	1155:1157	Thermogravimetric analysis shows that NCC has relatively high thermal stability ranging from 429 to 437 °C. Thus, this characteristic of NCC has the potential to be applied as a reinforcing agent in various fields of polymer composites.					
35388964	0	0	theme	Conductive	85:94	arg1	Composites					96:105	Conductive Composites	85:105	Conductive Composites	85:105	Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites.					
35388964	1	1	theme	working	162:168	arg1	range					170:174	a broader working range	152:174	a broader working range	152:174	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	7	2	theme	human-body-related	1178:1195	arg1	tests					1205:1209	human-body-related sensing tests	1178:1209	human-body-related sensing tests	1178:1209	Finally, human-body-related sensing tests and a self-correction system in fitness are designed and demonstrated.					
35388964	6	3	theme	small-angle	1097:1107	arg1	scattering					1115:1124	in situ small-angle x-ray scattering	1089:1124	in situ small-angle x-ray scattering	1089:1124	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	5	4	theme	conductors	897:906	arg1	range					882:886	the working range	870:886	the working range (93%) of conductors based on AP-SS without polyrotaxanes	870:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	4	theme	conductors	897:906	arg1	%					891:891	93%	889:891	93%	889:891	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	4	5	theme	polymer	597:603	arg1	PU-SS					617:621	PU-SS	617:621	PU-SS	617:621	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	4	5	theme	polymer	597:603	arg1	substrates					605:614	polymer substrates	597:614	polymer substrates (PU-SS)	597:622	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	0	6	theme	Composites	96:105	arg1	Stretchability					67:80	the Stretchability	63:80	the Stretchability of Conductive Composites	63:105	Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites.					
35388964	6	7	theme	scattering	1115:1124	arg1	change					1072:1077	morphological change	1058:1077	morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments	1058:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	5	8	theme	higher	858:863	arg1	times					852:856	two times	848:856	two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	848:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	9	theme	polyrotaxanes	824:836	arg1	nature					814:819	the sliding nature	802:819	the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	802:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	10	theme	long	733:736	arg1	range					746:750	a long sensing range	731:750	a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	731:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	10	theme	long	733:736	arg1	%					756:756	190%	753:756	190%	753:756	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	2	11	theme	inhomogeneous	344:356	arg1	breakage					358:365	the inhomogeneous breakage	340:365	the inhomogeneous breakage of the conductive network	340:391	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	5	12	theme	sliding	806:812	arg1	nature					814:819	the sliding nature	802:819	the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	802:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	13	attach	derived	789:795	arg1	nature					814:819	the sliding nature	802:819	the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	802:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	13	attach	derived	789:795	arg2	dissipation					777:787	the energy dissipation	766:787	the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	766:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	2	14	theme	soft	284:287	arg1	elastomers					289:298	soft elastomers	284:298	soft elastomers	284:298	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	3	15	theme	self-healable	440:452	arg1	conductor					454:462	a highly stretchable and self-healable conductor	415:462	a highly stretchable and self-healable conductor	415:462	Here, a highly stretchable and self-healable conductor is reported by adopting polyrotaxane and disulfide bonds into the binding layer.					
35388964	5	16	theme	sensing	738:744	arg1	range					746:750	a long sensing range	731:750	a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	731:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	16	theme	sensing	738:744	arg1	%					756:756	190%	753:756	190%	753:756	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	17	theme	energy	770:775	arg1	dissipation					777:787	the energy dissipation	766:787	the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	766:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	0	18	theme	Sliding	0:6	arg1	Molecules					21:29	Sliding Cyclodextrin Molecules	0:29	Sliding Cyclodextrin Molecules along Polymer Chains	0:50	Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites.					
35388964	0	19	theme	Cyclodextrin	8:19	arg1	Molecules					21:29	Sliding Cyclodextrin Molecules	0:29	Sliding Cyclodextrin Molecules along Polymer Chains	0:50	Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites.					
35388964	3	20	theme	stretchable	424:434	arg1	conductor					454:462	a highly stretchable and self-healable conductor	415:462	a highly stretchable and self-healable conductor	415:462	Here, a highly stretchable and self-healable conductor is reported by adopting polyrotaxane and disulfide bonds into the binding layer.					
35388964	1	21	with	demand	112:117	arg1	range					170:174	a broader working range	152:174	a broader working range	152:174	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	2	22	theme	working	319:325	arg1	range					327:331	low working range	315:331	low working range due to the inhomogeneous breakage of the conductive network	315:391	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	2	23	theme	network	385:391	arg1	breakage					358:365	the inhomogeneous breakage	340:365	the inhomogeneous breakage of the conductive network	340:391	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	7	24	theme	sensing	1197:1203	arg1	tests					1205:1209	human-body-related sensing tests	1178:1209	human-body-related sensing tests	1178:1209	Finally, human-body-related sensing tests and a self-correction system in fitness are designed and demonstrated.					
35388964	2	25	theme	low	315:317	arg1	range					327:331	low working range	315:331	low working range due to the inhomogeneous breakage of the conductive network	315:391	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	4	26	theme	silver	628:633	arg1	nanowires					635:643	silver nanowires	628:643	silver nanowires (AgNWs)	628:651	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	4	26	theme	silver	628:633	arg1	AgNWs					646:650	AgNWs	646:650	AgNWs	646:650	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	6	27	theme	in	1089:1090	arg1	scattering					1115:1124	in situ small-angle x-ray scattering	1089:1124	in situ small-angle x-ray scattering	1089:1124	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	6	28	theme	x-ray	1109:1113	arg1	scattering					1115:1124	in situ small-angle x-ray scattering	1089:1124	in situ small-angle x-ray scattering	1089:1124	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	6	29	theme	AgNWs	1082:1086	arg1	change					1072:1077	morphological change	1058:1077	morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments	1058:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	2	30	theme	conductive	374:383	arg1	network					385:391	the conductive network	370:391	the conductive network	370:391	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	5	31	theme	working	874:880	arg1	range					882:886	the working range	870:886	the working range (93%) of conductors based on AP-SS without polyrotaxanes	870:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	31	theme	working	874:880	arg1	%					891:891	93%	889:891	93%	889:891	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	32	theme	stretchable	704:714	arg1	conductor					716:724	the stretchable conductor	700:724	the stretchable conductor	700:724	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	6	33	theme	effect	984:989	arg1	mechanism					963:971	the mechanism	959:971	the mechanism of sliding effect for the polyrotaxanes in the elastomers	959:1029	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	1	34	theme	wide	194:197	arg1	application					199:209	wide application	194:209	wide application in wearable sensors and e-skin	194:240	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	1	35	theme	wearable	214:221	arg1	sensors					223:229	wearable sensors	214:229	wearable sensors	214:229	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	0	36	theme	Polymer	37:43	arg1	Chains					45:50	Polymer Chains	37:50	Polymer Chains	37:50	Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites.					
35388964	5	37	theme	due	759:761	arg1	range					746:750	a long sensing range	731:750	a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes	731:943	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	5	37	theme	due	759:761	arg1	%					756:756	190%	753:756	190%	753:756	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	6	38	dep	in	1089:1090	arg1	situ					1092:1095	situ	1092:1095	situ	1092:1095	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	6	39	theme	sliding	976:982	arg1	effect					984:989	sliding effect	976:989	sliding effect	976:989	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	7	40	theme	self-correction	1217:1231	arg1	system					1233:1238	a self-correction system	1215:1238	a self-correction system	1215:1238	Finally, human-body-related sensing tests and a self-correction system in fitness are designed and demonstrated.					
35388964	6	41	theme	experiments	1156:1166	arg1	change					1072:1077	morphological change	1058:1077	morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments	1058:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	3	42	theme	disulfide	505:513	arg1	bonds					515:519	disulfide bonds	505:519	disulfide bonds	505:519	Here, a highly stretchable and self-healable conductor is reported by adopting polyrotaxane and disulfide bonds into the binding layer.					
35388964	6	43	theme	relaxation	1145:1154	arg1	experiments					1156:1166	stress relaxation experiments	1138:1166	stress relaxation experiments	1138:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	1	44	from	application	199:209	arg1	e-skin					235:240	e-skin	235:240	e-skin	235:240	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	1	44	from	application	199:209	arg1	sensors					223:229	wearable sensors	214:229	wearable sensors	214:229	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	1	45	theme	stretchable	123:133	arg1	electronics					135:145	stretchable electronics	123:145	stretchable electronics	123:145	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35388964	4	46	theme	binding	549:555	arg1	PR-SS					564:568	PR-SS	564:568	PR-SS	564:568	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	4	46	theme	binding	549:555	arg1	layer					557:561	The binding layer	545:561	The binding layer (PR-SS)	545:569	The binding layer (PR-SS) builds the bridge between polymer substrates (PU-SS) and silver nanowires (AgNWs).					
35388964	5	47	theme	sliding	675:681	arg1	molecules					683:691	sliding molecules	675:691	sliding molecules	675:691	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	6	48	theme	stress	1138:1143	arg1	experiments					1156:1166	stress relaxation experiments	1138:1166	stress relaxation experiments	1138:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	6	49	from	polyrotaxanes	999:1011	arg1	elastomers					1020:1029	the elastomers	1016:1029	the elastomers	1016:1029	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	6	50	theme	morphological	1058:1070	arg1	change					1072:1077	morphological change	1058:1077	morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments	1058:1166	Furthermore, the mechanism of sliding effect for the polyrotaxanes in the elastomers is investigated by SEM for morphological change of AgNWs, in situ small-angle x-ray scattering, as well as stress relaxation experiments.					
35388964	5	51	theme	molecules	683:691	arg1	incorporation					658:670	The incorporation	654:670	The incorporation of sliding molecules	654:691	The incorporation of sliding molecules endows the stretchable conductor with a long sensing range (190%) due to the energy dissipation derived from the sliding nature of polyrotaxanes, which is two times higher than the working range (93%) of conductors based on AP-SS without polyrotaxanes.					
35388964	7	52	from	system	1233:1238	arg1	fitness					1243:1249	fitness	1243:1249	fitness	1243:1249	Finally, human-body-related sensing tests and a self-correction system in fitness are designed and demonstrated.					
35388964	2	53	theme	stretchable	252:262	arg1	conductors					264:273	stretchable conductors	252:273	stretchable conductors based on soft elastomers	252:298	However, stretchable conductors based on soft elastomers always exhibit low working range due to the inhomogeneous breakage of the conductive network when stretched.					
35388964	3	54	theme	binding	530:536	arg1	layer					538:542	the binding layer	526:542	the binding layer	526:542	Here, a highly stretchable and self-healable conductor is reported by adopting polyrotaxane and disulfide bonds into the binding layer.					
35388964	7	55	from	tests	1205:1209	arg1	fitness					1243:1249	fitness	1243:1249	fitness	1243:1249	Finally, human-body-related sensing tests and a self-correction system in fitness are designed and demonstrated.					
35388964	1	56	theme	broader	154:160	arg1	range					170:174	a broader working range	152:174	a broader working range	152:174	The demand for stretchable electronics with a broader working range is increasing for wide application in wearable sensors and e-skin.					
35421653	6	0	theme	hardness	939:946	arg1	value					948:952	the final hardness value	929:952	the final hardness value of the fruits coated with composite films	929:994	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	6	0	theme	hardness	939:946	arg1	4.94 ± 0.23 kg/cm3					1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	2	1	theme	good	344:347	arg1	stability					357:365	good thermal stability	344:365	good thermal stability	344:365	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	1	2	theme	phosphonium	237:247	arg1	bromide					249:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide	207:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP)	207:266	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	1	2	theme	phosphonium	237:247	arg1	HA-CS-NP					258:265	HA-CS-NP	258:265	HA-CS-NP	258:265	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	7	3	theme	broad	1144:1148	arg1	prospects					1150:1158	broad prospects	1144:1158	broad prospects	1144:1158	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	0	4	theme	phosphate	111:119	arg1	salt					121:124	quaternary phosphate salt	100:124	quaternary phosphate salt	100:124	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	3	5	from	elongation	479:488	arg1	ratio					544:548	the weight ratio	533:548	the weight ratio of 3/7	533:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	3	6	theme	composite	515:523	arg1	film					525:528	HA-CS-NP/PVA composite film	502:528	HA-CS-NP/PVA composite film at the weight ratio of 3/7	502:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	6	7	theme	rot	1059:1061	arg1	index					1063:1067	the rot index	1055:1067	the rot index	1055:1067	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	0	8	theme	quaternary	100:109	arg1	salt					121:124	quaternary phosphate salt	100:124	quaternary phosphate salt	100:124	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	3	9	theme	film	525:528	arg1	elongation					479:488	elongation	479:488	elongation	479:488	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	3	9	theme	film	525:528	arg1	strength					466:473	tensile strength	458:473	tensile strength	458:473	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	4	10	theme	Mango	660:664	arg1	lagenarium					669:678	Mango C. lagenarium	660:678	Mango C. lagenarium	660:678	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	3	11	from	break	493:497	arg1	elongation					479:488	elongation	479:488	elongation	479:488	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	3	11	from	break	493:497	arg1	strength					466:473	tensile strength	458:473	tensile strength	458:473	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	4	12	from	rates	632:636	arg1	lagenarium					669:678	Mango C. lagenarium	660:678	Mango C. lagenarium	660:678	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	4	12	from	rates	632:636	arg1	day					713:715	day 6	713:717	day 6	713:717	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	4	13	theme	inhibition	621:630	arg1	rates					632:636	the inhibition rates	617:636	the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium	617:678	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	4	13	theme	inhibition	621:630	arg1	%					742:742	up to 80.92 ± 4.12%	724:742	up to 80.92 ± 4.12%	724:742	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	7	14	theme	multifunctional	1103:1117	arg1	coating					1132:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	3	15	theme	HA-CS-NP/PVA	502:513	arg1	film					525:528	HA-CS-NP/PVA composite film	502:528	HA-CS-NP/PVA composite film at the weight ratio of 3/7	502:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	7	16	theme	food	1182:1185	arg1	packaging					1187:1195	food packaging	1182:1195	food packaging	1182:1195	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	2	17	theme	multifunctional	293:307	arg1	film					334:337	a multifunctional food packaging composite film	291:337	a multifunctional food packaging composite film with good thermal stability and antibacterial functions	291:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	2	18	theme	antibacterial	371:383	arg1	functions					385:393	antibacterial functions	371:393	antibacterial functions	371:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	2	19	theme	vinyl	432:436	arg1	poly					426:429	poly	426:429	poly (vinyl alcohol) (PVA)	426:451	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	2	19	theme	vinyl	432:436	arg1	alcohol					438:444	vinyl alcohol	432:444	vinyl alcohol	432:444	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	5	20	theme	weight	773:778	arg1	loss					780:783	the weight loss	769:783	the weight loss of experimental groups	769:806	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	5	21	theme	experimental	788:799	arg1	groups					801:806	experimental groups	788:806	experimental groups	788:806	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	5	22	dep	reduced	893:899	arg1	23.96 ± 2.46 g/206 ± 7.25 g					813:839	23.96 ± 2.46 g/206 ± 7.25 g	813:839	23.96 ± 2.46 g/206 ± 7.25 g	813:839	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	5	22	dep	reduced	893:899	arg1	papaya					884:889	papaya	884:889	papaya	884:889	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	5	22	dep	reduced	893:899	arg1	mangoes					842:848	mangoes	842:848	mangoes	842:848	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	5	22	dep	reduced	893:899	arg1	59.45 ± 3.06 g/496 ± 6.37 g					855:881	59.45 ± 3.06 g/496 ± 6.37 g	855:881	59.45 ± 3.06 g/496 ± 6.37 g	855:881	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	3	23	from	strength	466:473	arg1	ratio					544:548	the weight ratio	533:548	the weight ratio of 3/7	533:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	0	24	dep	ammonium	82:89	arg1	salt					91:94	salt	91:94	salt	91:94	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	0	24	dep	ammonium	82:89	arg1	salt					121:124	quaternary phosphate salt	100:124	quaternary phosphate salt	100:124	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	5	25	theme	CK	759:760	arg1	group					762:766	CK group	759:766	CK group	759:766	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	4	26	theme	Papaya	684:689	arg1	gloeosporioides					694:708	Papaya C. gloeosporioides	684:708	Papaya C. gloeosporioides	684:708	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	0	27	theme	derivatives	45:55	arg1	characterization					16:31	characterization	16:31	characterization	16:31	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	0	27	theme	derivatives	45:55	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	0	28	theme	tropical	144:151	arg1	preservation					159:170	tropical fruit preservation	144:170	tropical fruit preservation	144:170	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	6	29	theme	composite	980:988	arg1	films					990:994	composite films	980:994	composite films	980:994	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	6	30	theme	fruits	961:966	arg1	value					948:952	the final hardness value	929:952	the final hardness value of the fruits coated with composite films	929:994	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	6	30	theme	fruits	961:966	arg1	4.94 ± 0.23 kg/cm3					1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	0	31	theme	chitosan	36:43	arg1	derivatives					45:55	chitosan derivatives	36:55	chitosan derivatives	36:55	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	0	32	from	ammonium	82:89	arg1	preservation					159:170	tropical fruit preservation	144:170	tropical fruit preservation	144:170	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	0	33	from	effect	134:139	arg1	preservation					159:170	tropical fruit preservation	144:170	tropical fruit preservation	144:170	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	1	34	theme	5-Carboxypentyl	208:222	arg1	bromide					249:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide	207:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP)	207:266	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	1	34	theme	5-Carboxypentyl	208:222	arg1	HA-CS-NP					258:265	HA-CS-NP	258:265	HA-CS-NP	258:265	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	7	35	theme	HA-CS-NP/PVA	1119:1130	arg1	coating					1132:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	3	36	theme	tensile	458:464	arg1	strength					466:473	tensile strength	458:473	tensile strength	458:473	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	4	37	dep	80.92 ± 4.12	730:741	arg1	to					727:728	to	727:728	to	727:728	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	2	38	with	film	334:337	arg1	functions					385:393	antibacterial functions	371:393	antibacterial functions	371:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	2	38	with	film	334:337	arg1	stability					357:365	good thermal stability	344:365	good thermal stability	344:365	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	0	39	theme	fruit	153:157	arg1	preservation					159:170	tropical fruit preservation	144:170	tropical fruit preservation	144:170	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	3	40	theme	3/7	553:555	arg1	ratio					544:548	the weight ratio	533:548	the weight ratio of 3/7	533:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	2	41	theme	composite	324:332	arg1	film					334:337	a multifunctional food packaging composite film	291:337	a multifunctional food packaging composite film with good thermal stability and antibacterial functions	291:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	3	42	theme	weight	537:542	arg1	ratio					544:548	the weight ratio	533:548	the weight ratio of 3/7	533:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	4	43	theme	HA-CS-NP	641:648	arg1	rates					632:636	the inhibition rates	617:636	the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium	617:678	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	4	43	theme	HA-CS-NP	641:648	arg1	%					742:742	up to 80.92 ± 4.12%	724:742	up to 80.92 ± 4.12%	724:742	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	2	44	theme	packaging	314:322	arg1	film					334:337	a multifunctional food packaging composite film	291:337	a multifunctional food packaging composite film with good thermal stability and antibacterial functions	291:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	4	45	theme	C.	691:692	arg1	gloeosporioides					694:708	Papaya C. gloeosporioides	684:708	Papaya C. gloeosporioides	684:708	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	3	46	dep	strength	466:473	arg1	The					454:456	The	454:456	The	454:456	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	2	47	theme	food	309:312	arg1	film					334:337	a multifunctional food packaging composite film	291:337	a multifunctional food packaging composite film with good thermal stability and antibacterial functions	291:393	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	4	48	theme	C.	666:667	arg1	lagenarium					669:678	Mango C. lagenarium	660:678	Mango C. lagenarium	660:678	And, the inhibition rates of HA-CS-NP (0.5%) on Mango C. lagenarium and Papaya C. gloeosporioides on day 6 were up to 80.92 ± 4.12%.					
35421653	7	49	contain	has	1140:1142	arg2	prospects					1150:1158	broad prospects	1144:1158	broad prospects	1144:1158	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	7	49	contain	has	1140:1142	arg1	coating					1132:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating	1099:1138	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	5	50	theme	groups	801:806	arg1	loss					780:783	the weight loss	769:783	the weight loss of experimental groups	769:806	Compared with CK group, the weight loss of experimental groups were 23.96 ± 2.46 g/206 ± 7.25 g (mangoes) and 59.45 ± 3.06 g/496 ± 6.37 g (papaya), reduced by 35.76 ± 1.15%.					
35421653	3	51	from	ratio	544:548	arg1	elongation					479:488	elongation	479:488	elongation	479:488	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	3	51	from	ratio	544:548	arg1	strength					466:473	tensile strength	458:473	tensile strength	458:473	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	3	51	from	ratio	544:548	arg1	film					525:528	HA-CS-NP/PVA composite film	502:528	HA-CS-NP/PVA composite film at the weight ratio of 3/7	502:555	The tensile strength and elongation at break of HA-CS-NP/PVA composite film at the weight ratio of 3/7 were 20.32 ± 1.02 MPa and 65.73 ± 3.29%, respectively.					
35421653	1	52	theme	triphenyl	226:234	arg1	bromide					249:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide	207:255	(5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP)	207:266	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	1	52	theme	triphenyl	226:234	arg1	HA-CS-NP					258:265	HA-CS-NP	258:265	HA-CS-NP	258:265	In this paper, HACC modified with (5-Carboxypentyl) (triphenyl) phosphonium bromide (HA-CS-NP) was synthesized.					
35421653	0	53	theme	quaternary	71:80	arg1	ammonium					82:89	quaternary ammonium salt and quaternary phosphate salt	71:124	quaternary ammonium salt and quaternary phosphate salt	71:124	Preparation and characterization of chitosan derivatives modified with quaternary ammonium salt and quaternary phosphate salt and its effect on tropical fruit preservation.					
35421653	7	54	theme	packaging	1187:1195	arg1	application					1167:1177	the application	1163:1177	the application of food packaging	1163:1195	The multifunctional HA-CS-NP/PVA coating has broad prospects in the application of food packaging.					
35421653	2	55	theme	thermal	349:355	arg1	stability					357:365	good thermal stability	344:365	good thermal stability	344:365	Then, a multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated by HA-CS-NP and poly (vinyl alcohol) (PVA).					
35421653	6	56	theme	final	933:937	arg1	value					948:952	the final hardness value	929:952	the final hardness value of the fruits coated with composite films	929:994	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35421653	6	56	theme	final	933:937	arg1	4.94 ± 0.23 kg/cm3					1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	4.94 ± 0.23 kg/cm3	1000:1017	Moreover, the final hardness value of the fruits coated with composite films was 4.94 ± 0.23 kg/cm3 and increased by 20.79 ± 1.04%, and the rot index was reduced by 71.43 ± 3.24%.					
35789841	4	0	theme	activity	776:783	arg1	strategy					815:822	an activity pattern-based differentiation strategy	773:822	an activity pattern-based differentiation strategy for aglycone sterics	773:843	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	5	1	theme	sterics-selective	927:943	arg1	remodeling					952:961	aglycone sterics-selective glycan remodeling	918:961	aglycone sterics-selective glycan remodeling in a complex biological environment	918:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	3	2	theme	glycan	559:564	arg1	remodeling					566:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	6	3	with	adjustment	1042:1051	arg1	cues					1067:1070	external cues	1058:1070	external cues	1058:1070	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	4	4	theme	polymer	656:662	arg1	length					664:669	tuning polymer length	649:669	tuning polymer length	649:669	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	6	5	theme	remodeling	1193:1202	arg1	enhancement					1167:1177	an unexpected enhancement	1153:1177	an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells	1153:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	6	6	theme	polymer	1027:1033	arg1	length					1035:1040	the polymer length	1023:1040	the polymer length adjustment with external cues	1023:1070	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	6	7	theme	remodeling	1236:1245	arg1	remodeling					1193:1202	glycolipid remodeling	1182:1202	glycolipid remodeling	1182:1202	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	6	7	theme	remodeling	1236:1245	arg1	control					1218:1224	temporal control	1209:1224	temporal control of glycan remodeling on live cells	1209:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	2	8	theme	remodeling	389:398	arg1	selectivity					367:377	the selectivity	363:377	the selectivity of glycan remodeling	363:398	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	4	9	theme	tuning	649:654	arg1	length					664:669	tuning polymer length	649:669	tuning polymer length	649:669	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	6	10	theme	glycan	1229:1234	arg1	remodeling					1236:1245	glycan remodeling	1229:1245	glycan remodeling	1229:1245	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	3	11	theme	functional	603:612	arg1	polymers					614:621	functional polymers	603:621	functional polymers from glycoenzyme	603:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	6	12	theme	multi-faceted	1117:1129	arg1	fashion					1131:1137	a multi-faceted fashion	1115:1137	a multi-faceted fashion	1115:1137	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	4	13	theme	composites	699:708	arg1	series					674:679	a series	672:679	a series of enzyme-polymer composites with varying substrate permeability	672:744	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	3	14	theme	polymers	614:621	arg1	grafting					591:598	controlled grafting	580:598	controlled grafting of functional polymers from glycoenzyme	580:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	6	15	from	control	1218:1224	arg1	cells					1255:1259	live cells	1250:1259	live cells	1250:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	16	theme	glycans	80:86	arg1	remodeling					66:75	Precision remodeling	56:75	Precision remodeling of glycans in their native environments	56:115	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	3	17	theme	aglycone	522:529	arg1	remodeling					566:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	5	18	theme	remodeling	952:961	arg1	implementation					864:877	the implementation	860:877	the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment	860:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	1	19	contain	has	184:186	arg2	implications					215:226	important biotechnological implications	188:226	important biotechnological implications	188:226	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	1	19	contain	has	184:186	arg1	remodeling					66:75	Precision remodeling	56:75	Precision remodeling of glycans in their native environments	56:115	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	5	20	theme	glycan	945:950	arg1	remodeling					952:961	aglycone sterics-selective glycan remodeling	918:961	aglycone sterics-selective glycan remodeling in a complex biological environment	918:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	2	21	theme	complex	457:463	arg1	scenarios					476:484	complex biological scenarios	457:484	complex biological scenarios	457:484	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	6	22	theme	unexpected	1156:1165	arg1	enhancement					1167:1177	an unexpected enhancement	1153:1177	an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells	1153:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	23	from	remodeling	66:75	arg1	environments					104:115	their native environments	91:115	their native environments	91:115	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	1	24	theme	biotechnological	198:213	arg1	implications					215:226	important biotechnological implications	188:226	important biotechnological implications	188:226	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	5	25	from	screening	903:911	arg1	environment					987:997	a complex biological environment	966:997	a complex biological environment	966:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	6	26	theme	glycolipid	1182:1191	arg1	remodeling					1193:1202	glycolipid remodeling	1182:1202	glycolipid remodeling	1182:1202	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	3	27	theme	sterics-selective	531:547	arg1	remodeling					566:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	5	28	theme	complex	968:974	arg1	environment					987:997	a complex biological environment	966:997	a complex biological environment	966:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	5	29	theme	screening	903:911	arg1	implementation					864:877	the implementation	860:877	the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment	860:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	6	30	from	enhancement	1167:1177	arg1	cells					1255:1259	live cells	1250:1259	live cells	1250:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	31	theme	native	97:102	arg1	environments					104:115	their native environments	91:115	their native environments	91:115	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	5	32	theme	biological	976:985	arg1	environment					987:997	a complex biological environment	966:997	a complex biological environment	966:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	6	33	from	remodeling	1193:1202	arg1	cells					1255:1259	live cells	1250:1259	live cells	1250:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	2	34	theme	diversity	350:358	arg1	influence					321:329	the influence	317:329	the influence of aglycone-steric diversity on the selectivity of glycan remodeling	317:398	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	5	35	from	environment	987:997	arg1	implementation					864:877	the implementation	860:877	the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment	860:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	0	36	theme	glycan	37:42	arg1	remodeling					44:53	enzymatic glycan remodeling	27:53	enzymatic glycan remodeling	27:53	Aglycone sterics-selective enzymatic glycan remodeling.					
35789841	4	37	theme	aglycone	828:835	arg1	sterics					837:843	aglycone sterics	828:843	aglycone sterics	828:843	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	2	38	theme	aglycone-steric	334:348	arg1	diversity					350:358	aglycone-steric diversity	334:358	aglycone-steric diversity	334:358	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	2	39	theme	biological	465:474	arg1	scenarios					476:484	complex biological scenarios	457:484	complex biological scenarios	457:484	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	0	40	theme	enzymatic	27:35	arg1	remodeling					44:53	enzymatic glycan remodeling	27:53	enzymatic glycan remodeling	27:53	Aglycone sterics-selective enzymatic glycan remodeling.					
35789841	6	41	theme	aglycone-steric	1084:1098	arg1	selectivity					1100:1110	aglycone-steric selectivity	1084:1110	aglycone-steric selectivity	1084:1110	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	42	theme	important	188:196	arg1	implications					215:226	important biotechnological implications	188:226	important biotechnological implications	188:226	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	1	43	theme	clinical	241:248	arg1	diagnosis					250:258	clinical diagnosis	241:258	clinical diagnosis	241:258	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	4	44	theme	pattern-based	785:797	arg1	strategy					815:822	an activity pattern-based differentiation strategy	773:822	an activity pattern-based differentiation strategy for aglycone sterics	773:843	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	4	45	theme	substrate	723:731	arg1	permeability					733:744	varying substrate permeability	715:744	varying substrate permeability	715:744	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	1	46	theme	diagnosis	250:258	arg1	fields					231:236	fields	231:236	fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth	231:305	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	6	47	theme	control	1218:1224	arg1	enhancement					1167:1177	an unexpected enhancement	1153:1177	an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells	1153:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	4	48	theme	enzyme-polymer	684:697	arg1	composites					699:708	enzyme-polymer composites	684:708	enzyme-polymer composites with varying substrate permeability	684:744	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	5	49	from	remodeling	952:961	arg1	environment					987:997	a complex biological environment	966:997	a complex biological environment	966:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	4	50	theme	varying	715:721	arg1	permeability					733:744	varying substrate permeability	715:744	varying substrate permeability	715:744	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	2	51	theme	glycan	382:387	arg1	remodeling					389:398	glycan remodeling	382:398	glycan remodeling	382:398	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	5	52	theme	partner	895:901	arg1	screening					903:911	glycolipid's partner screening	882:911	glycolipid's partner screening	882:911	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	6	53	theme	external	1058:1065	arg1	cues					1067:1070	external cues	1058:1070	external cues	1058:1070	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	3	54	theme	remodeling	566:575	arg1	achievement					507:517	the achievement	503:517	the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme	503:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	3	55	theme	enzymatic	549:557	arg1	remodeling					566:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	aglycone sterics-selective enzymatic glycan remodeling	522:575	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	4	56	theme	differentiation	799:813	arg1	strategy					815:822	an activity pattern-based differentiation strategy	773:822	an activity pattern-based differentiation strategy for aglycone sterics	773:843	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	5	57	from	implementation	864:877	arg1	environment					987:997	a complex biological environment	966:997	a complex biological environment	966:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	1	58	dep	diagnosis	250:258	arg1	forth					301:305	forth	301:305	forth	301:305	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	1	59	theme	glycan-mediated	146:160	arg1	events					173:178	glycan-mediated biological events	146:178	glycan-mediated biological events	146:178	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	3	60	from	glycoenzyme	628:638	arg1	grafting					591:598	controlled grafting	580:598	controlled grafting of functional polymers from glycoenzyme	580:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	3	60	from	glycoenzyme	628:638	arg1	polymers					614:621	functional polymers	603:621	functional polymers from glycoenzyme	603:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	1	61	theme	glyco-immune	261:272	arg1	therapy					285:291	glyco-immune checkpoint therapy	261:291	glyco-immune checkpoint therapy	261:291	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	6	62	theme	live	1250:1253	arg1	cells					1255:1259	live cells	1250:1259	live cells	1250:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	6	63	from	cells	1255:1259	arg1	enhancement					1167:1177	an unexpected enhancement	1153:1177	an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells	1153:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	64	theme	biological	162:171	arg1	events					173:178	glycan-mediated biological events	146:178	glycan-mediated biological events	146:178	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	2	65	from	influence	321:329	arg1	selectivity					367:377	the selectivity	363:377	the selectivity of glycan remodeling	363:398	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	1	66	theme	checkpoint	274:283	arg1	therapy					285:291	glyco-immune checkpoint therapy	261:291	glyco-immune checkpoint therapy	261:291	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	4	67	with	composites	699:708	arg1	permeability					733:744	varying substrate permeability	715:744	varying substrate permeability	715:744	Through tuning polymer length, a series of enzyme-polymer composites with varying substrate permeability are prepared, which afford an activity pattern-based differentiation strategy for aglycone sterics.					
35789841	1	68	theme	Precision	56:64	arg1	remodeling					66:75	Precision remodeling	56:75	Precision remodeling of glycans in their native environments	56:115	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	2	69	from	application	442:452	arg1	scenarios					476:484	complex biological scenarios	457:484	complex biological scenarios	457:484	However, the influence of aglycone-steric diversity on the selectivity of glycan remodeling has been largely overlooked, limiting the application in complex biological scenarios.					
35789841	6	70	theme	temporal	1209:1216	arg1	control					1218:1224	temporal control	1209:1224	temporal control of glycan remodeling on live cells	1209:1259	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	1	71	theme	therapy	285:291	arg1	fields					231:236	fields	231:236	fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth	231:305	Precision remodeling of glycans in their native environments is pivotal for understanding glycan-mediated biological events and has important biotechnological implications in fields of clinical diagnosis, glyco-immune checkpoint therapy, and so forth.					
35789841	6	72	theme	adjustment	1042:1051	arg1	length					1035:1040	the polymer length	1023:1040	the polymer length adjustment with external cues	1023:1070	We further orchestrate the polymer length adjustment with external cues to regulate aglycone-steric selectivity in a multi-faceted fashion, resulting in an unexpected enhancement of glycolipid remodeling, and temporal control of glycan remodeling on live cells.					
35789841	5	73	theme	aglycone	918:925	arg1	remodeling					952:961	aglycone sterics-selective glycan remodeling	918:961	aglycone sterics-selective glycan remodeling in a complex biological environment	918:997	This leads to the implementation of glycolipid's partner screening, and aglycone sterics-selective glycan remodeling in a complex biological environment.					
35789841	3	74	theme	controlled	580:589	arg1	grafting					591:598	controlled grafting	580:598	controlled grafting of functional polymers from glycoenzyme	580:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35789841	3	75	from	grafting	591:598	arg1	glycoenzyme					628:638	glycoenzyme	628:638	glycoenzyme	628:638	Here, we report the achievement of aglycone sterics-selective enzymatic glycan remodeling by controlled grafting of functional polymers from glycoenzyme.					
35597888	6	0	from	data	920:923	arg1	model					893:897	an ecology model	882:897	an ecology model	882:897	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	4	1	theme	long-term	474:482	arg1	dynamics					484:491	the long-term dynamics	470:491	the long-term dynamics of the gut microbiome	470:513	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	9	2	theme	gut	1542:1544	arg1	microbiome					1546:1555	synthetic and natural human gut microbiome	1514:1555	microbiome	1546:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	8	3	theme	resistant	1455:1463	arg1	starch					1465:1470	dietary resistant starch	1447:1470	dietary resistant starch	1447:1470	We showed that our methods and major findings were generalizable to dietary resistant starch.					
35597888	5	4	theme	rapid	753:757	arg1	response					759:766	a generally rapid response	741:766	a generally rapid response followed by gradual stabilization to new equilibria	741:818	We found that inulin produced a generally rapid response followed by gradual stabilization to new equilibria, and those dynamics were baseline-dependent.					
35597888	6	5	theme	baseline	1092:1099	arg1	dependence					1101:1110	the baseline dependence	1088:1110	the baseline dependence of microbiome density and community composition dynamics	1088:1167	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	7	6	theme	SCFAs	1345:1349	arg1	prediction					1331:1340	the prediction	1327:1340	the prediction of SCFAs	1327:1349	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	3	7	theme	baseline	344:351	arg1	microbiome					357:366	their baseline gut microbiome	338:366	their baseline gut microbiome	338:366	Previous research showed that each individual's response to fibers depends on their baseline gut microbiome, but the ecology driving microbiota remodeling during fiber intake remained unclear.					
35597888	7	8	theme	inulin	1251:1256	arg1	responders					1258:1267	inulin responders	1251:1267	inulin responders	1251:1267	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	9	9	dep	fiber	1580:1584	arg1	response					1560:1567	response	1560:1567	response	1560:1567	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	10	10	theme	dietary	1747:1753	arg1	changes					1755:1761	dietary changes	1747:1761	dietary changes	1747:1761	This study emphasizes the importance of ecological modeling to understand microbiome responses to dietary changes and the need for personalized interventions.					
35597888	2	11	dep	composition	160:170	arg1	the					156:158	the	156:158	the	156:158	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	6	12	theme	ecology	885:891	arg1	model					893:897	an ecology model	882:897	an ecology model	882:897	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	10	13	theme	personalized	1780:1791	arg1	interventions					1793:1805	personalized interventions	1780:1805	personalized interventions	1780:1805	This study emphasizes the importance of ecological modeling to understand microbiome responses to dietary changes and the need for personalized interventions.					
35597888	3	14	theme	fiber	422:426	arg1	intake					428:433	fiber intake	422:433	fiber intake	422:433	Previous research showed that each individual's response to fibers depends on their baseline gut microbiome, but the ecology driving microbiota remodeling during fiber intake remained unclear.					
35597888	4	15	theme	isogenic	554:561	arg1	mice					563:566	isogenic mice	554:566	isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose	554:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	10	16	theme	modeling	1700:1707	arg1	importance					1675:1684	the importance	1671:1684	the importance of ecological modeling	1671:1707	This study emphasizes the importance of ecological modeling to understand microbiome responses to dietary changes and the need for personalized interventions.					
35597888	9	17	theme	dietary	1572:1578	arg1	fiber					1580:1584	dietary fiber	1572:1584	dietary fiber	1572:1584	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	4	18	theme	fiber	628:632	arg1	inulin					634:639	the fermentable fiber inulin	612:639	the fermentable fiber inulin	612:639	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	6	19	dep	inulin	1013:1018	arg1	response					1001:1008	response	1001:1008	response	1001:1008	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	7	20	theme	gut	1304:1306	arg1	variation					1291:1299	inter-individual variation	1274:1299	inter-individual variation of gut	1274:1306	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	1	21	theme	Dietary	72:78	arg1	fibers					80:85	Dietary fibers	72:85	Dietary fibers	72:85	Dietary fibers are generally thought to benefit intestinal health.					
35597888	7	22	theme	inter-individual	1274:1289	arg1	variation					1291:1299	inter-individual variation	1274:1299	inter-individual variation of gut	1274:1306	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	4	23	theme	resistant	645:653	arg1	starch					655:660	resistant starch	645:660	resistant starch	645:660	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	0	24	theme	Ecological	0:9	arg1	dynamics					11:18	Ecological dynamics	0:18	Ecological dynamics of the gut	0:29	Ecological dynamics of the gut microbiome in response to dietary fiber.					
35597888	10	25	theme	microbiome	1723:1732	arg1	responses					1734:1742	microbiome responses	1723:1742	microbiome responses to dietary changes and the need for personalized interventions	1723:1805	This study emphasizes the importance of ecological modeling to understand microbiome responses to dietary changes and the need for personalized interventions.					
35597888	0	26	dep	fiber	65:69	arg1	response					45:52	response	45:52	response	45:52	Ecological dynamics of the gut microbiome in response to dietary fiber.					
35597888	6	27	theme	interspecies	1053:1064	arg1	competition					1066:1076	interspecies competition	1053:1076	interspecies competition	1053:1076	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	3	28	theme	gut	353:355	arg1	microbiome					357:366	their baseline gut microbiome	338:366	their baseline gut microbiome	338:366	Previous research showed that each individual's response to fibers depends on their baseline gut microbiome, but the ecology driving microbiota remodeling during fiber intake remained unclear.					
35597888	4	29	theme	fatty	531:535	arg1	acids					537:541	short-chain fatty acids	519:541	short-chain fatty acids (SCFAs)	519:549	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	4	29	theme	fatty	531:535	arg1	SCFAs					544:548	SCFAs	544:548	SCFAs	544:548	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	3	30	theme	Previous	260:267	arg1	research					269:276	Previous research	260:276	Previous research	260:276	Previous research showed that each individual's response to fibers depends on their baseline gut microbiome, but the ecology driving microbiota remodeling during fiber intake remained unclear.					
35597888	8	31	theme	major	1410:1414	arg1	findings					1416:1423	major findings	1410:1423	major findings	1410:1423	We showed that our methods and major findings were generalizable to dietary resistant starch.					
35597888	10	32	theme	ecological	1689:1698	arg1	modeling					1700:1707	ecological modeling	1689:1707	ecological modeling	1689:1707	This study emphasizes the importance of ecological modeling to understand microbiome responses to dietary changes and the need for personalized interventions.					
35597888	6	33	theme	density	1126:1132	arg1	dynamics					1160:1167	microbiome density and community composition dynamics	1115:1167	microbiome density and community composition dynamics	1115:1167	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	6	34	theme	dynamics	1160:1167	arg1	dependence					1101:1110	the baseline dependence	1088:1110	the baseline dependence of microbiome density and community composition dynamics	1088:1167	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	6	35	theme	time-series	908:918	arg1	data					920:923	the time-series data	904:923	the time-series data	904:923	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	7	36	theme	responders	1258:1267	arg1	abundance					1238:1246	the abundance	1234:1246	the abundance of inulin responders	1234:1267	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	7	37	theme	Fecal	1170:1174	arg1	levels					1176:1181	Fecal levels	1170:1181	Fecal levels	1170:1181	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	7	37	theme	Fecal	1170:1174	arg1	propionate					1201:1210	propionate	1201:1210	propionate	1201:1210	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	6	38	theme	community	1138:1146	arg1	composition					1148:1158	community composition	1138:1158	community composition	1138:1158	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	6	39	theme	baseline	1030:1037	arg1	abundance					1039:1047	baseline abundance	1030:1047	baseline abundance	1030:1047	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	9	40	theme	inferred	1604:1611	arg1	interactions					1626:1637	interspecies interactions	1613:1637	the inferred interspecies interactions	1600:1637	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	4	41	theme	fermentable	616:626	arg1	inulin					634:639	the fermentable fiber inulin	612:639	the fermentable fiber inulin	612:639	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	0	42	theme	gut	27:29	arg1	dynamics					11:18	Ecological dynamics	0:18	Ecological dynamics of the gut	0:29	Ecological dynamics of the gut microbiome in response to dietary fiber.					
35597888	4	43	theme	microbiome	504:513	arg1	dynamics					484:491	the long-term dynamics	470:491	the long-term dynamics of the gut microbiome	470:513	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	4	43	theme	microbiome	504:513	arg1	SCFAs					544:548	SCFAs	544:548	SCFAs	544:548	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	4	43	theme	microbiome	504:513	arg1	acids					537:541	short-chain fatty acids	519:541	short-chain fatty acids (SCFAs)	519:549	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	3	44	theme	microbiota	393:402	arg1	remodeling					404:413	microbiota remodeling	393:413	microbiota remodeling during fiber intake	393:433	Previous research showed that each individual's response to fibers depends on their baseline gut microbiome, but the ecology driving microbiota remodeling during fiber intake remained unclear.					
35597888	5	45	theme	new	805:807	arg1	equilibria					809:818	new equilibria	805:818	new equilibria	805:818	We found that inulin produced a generally rapid response followed by gradual stabilization to new equilibria, and those dynamics were baseline-dependent.					
35597888	9	46	theme	time-series	1494:1504	arg1	data					1506:1509	time-series data	1494:1509	time-series data of synthetic and natural human gut microbiome	1494:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	2	47	from	impacts	145:151	arg1	composition					160:170	composition	160:170	composition	160:170	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	2	47	from	impacts	145:151	arg1	function					186:193	metabolic function	176:193	metabolic function	176:193	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	4	48	theme	gut	500:502	arg1	microbiome					504:513	the gut microbiome	496:513	the gut microbiome	496:513	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	6	49	theme	bacteria	952:959	arg1	bacteria					952:959	bacteria	952:959	bacteria	952:959	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	6	49	theme	bacteria	952:959	arg1	group					943:947	a group	941:947	a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics	941:1167	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	2	50	theme	microbiome	206:215	arg1	composition					160:170	composition	160:170	composition	160:170	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	2	50	theme	microbiome	206:215	arg1	function					186:193	metabolic function	176:193	metabolic function	176:193	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	9	51	theme	microbiome	1546:1555	arg1	data					1506:1509	time-series data	1494:1509	time-series data of synthetic and natural human gut microbiome	1494:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	4	52	theme	fiber	694:698	arg1	cellulose					700:708	the non-fermentable fiber cellulose	674:708	the non-fermentable fiber cellulose	674:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	5	53	theme	gradual	780:786	arg1	stabilization					788:800	gradual stabilization	780:800	gradual stabilization to new equilibria	780:818	We found that inulin produced a generally rapid response followed by gradual stabilization to new equilibria, and those dynamics were baseline-dependent.					
35597888	4	54	theme	short-chain	519:529	arg1	acids					537:541	short-chain fatty acids	519:541	short-chain fatty acids (SCFAs)	519:549	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	4	54	theme	short-chain	519:529	arg1	SCFAs					544:548	SCFAs	544:548	SCFAs	544:548	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	2	55	theme	gut	202:204	arg1	microbiome					206:215	the gut microbiome	198:215	the gut microbiome	198:215	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	4	56	theme	non-fermentable	678:692	arg1	cellulose					700:708	the non-fermentable fiber cellulose	674:708	the non-fermentable fiber cellulose	674:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	7	57	theme	learning	1362:1369	arg1	models					1371:1376	machine learning models	1354:1376	machine learning models	1354:1376	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	4	58	with	mice	563:566	arg1	baselines					593:601	distinct microbiota baselines	573:601	distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose	573:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	9	59	theme	interspecies	1613:1624	arg1	interactions					1626:1637	interspecies interactions	1613:1637	the inferred interspecies interactions	1600:1637	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	9	60	theme	synthetic	1514:1522	arg1	microbiome					1546:1555	synthetic and natural human gut microbiome	1514:1555	microbiome	1546:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	4	61	theme	distinct	573:580	arg1	baselines					593:601	distinct microbiota baselines	573:601	distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose	573:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35597888	7	62	dep	microbiome	1308:1317	arg1	impeded					1319:1325	impeded	1319:1325	impeded	1319:1325	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	1	63	theme	intestinal	120:129	arg1	health					131:136	intestinal health	120:136	intestinal health	120:136	Dietary fibers are generally thought to benefit intestinal health.					
35597888	6	64	theme	composition	1148:1158	arg1	dynamics					1160:1167	microbiome density and community composition dynamics	1115:1167	microbiome density and community composition dynamics	1115:1167	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	0	65	theme	dietary	57:63	arg1	fiber					65:69	dietary fiber	57:69	dietary fiber	57:69	Ecological dynamics of the gut microbiome in response to dietary fiber.					
35597888	2	66	theme	metabolic	176:184	arg1	function					186:193	metabolic function	176:193	metabolic function	176:193	Their impacts on the composition and metabolic function of the gut microbiome, however, vary greatly across individuals.					
35597888	8	67	theme	dietary	1447:1453	arg1	starch					1465:1470	dietary resistant starch	1447:1470	dietary resistant starch	1447:1470	We showed that our methods and major findings were generalizable to dietary resistant starch.					
35597888	9	68	theme	natural	1528:1534	arg1	microbiome					1546:1555	synthetic and natural human gut microbiome	1514:1555	microbiome	1546:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	6	69	theme	microbiome	1115:1124	arg1	density					1126:1132	microbiome density	1115:1132	microbiome density	1115:1132	We parameterized an ecology model from the time-series data, which revealed a group of bacteria whose growth significantly increased in response to inulin and whose baseline abundance and interspecies competition explained the baseline dependence of microbiome density and community composition dynamics.					
35597888	7	70	theme	SCFAs	1186:1190	arg1	levels					1176:1181	Fecal levels	1170:1181	Fecal levels	1170:1181	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	7	70	theme	SCFAs	1186:1190	arg1	propionate					1201:1210	propionate	1201:1210	propionate	1201:1210	Fecal levels of SCFAs, such as propionate, were associated with the abundance of inulin responders, yet inter-individual variation of gut microbiome impeded the prediction of SCFAs by machine learning models.					
35597888	9	71	theme	human	1536:1540	arg1	microbiome					1546:1555	synthetic and natural human gut microbiome	1514:1555	microbiome	1546:1555	Finally, we analyzed time-series data of synthetic and natural human gut microbiome in response to dietary fiber and validated the inferred interspecies interactions in vitro.					
35597888	4	72	theme	microbiota	582:591	arg1	baselines					593:601	distinct microbiota baselines	573:601	distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose	573:708	Here, we studied the long-term dynamics of the gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin and resistant starch compared to the non-fermentable fiber cellulose.					
35376973	7	0	theme	nitric	1174:1179	arg1	synthase					1187:1194	inducible nitric oxide synthase	1164:1194	inducible nitric oxide synthase (iNOS)	1164:1201	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	0	theme	nitric	1174:1179	arg1	iNOS					1197:1200	iNOS	1197:1200	iNOS	1197:1200	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	1	theme	factor	1338:1343	arg1	TGF-β1					1349:1354	TGF-β1	1349:1354	TGF-β1	1349:1354	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	1	theme	factor	1338:1343	arg1	β1					1345:1346	the anti-inflammatory mediator transforming growth factor β1	1287:1346	the anti-inflammatory mediator transforming growth factor β1 (TGF-β1)	1287:1355	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	10	2	theme	colonic	1920:1926	arg1	inflammation					1928:1939	ABx-induced colonic inflammation	1908:1939	ABx-induced colonic inflammation	1908:1939	• ITFs delayed the recovery of ABx-induced colonic inflammation.					
35376973	12	3	theme	B	2031:2031	arg1	cells					2033:2037	Treg and B cells	2022:2037	cells	2033:2037	• ITFs delayed the recovery of Treg and B cells in the LP.					
35376973	3	4	theme	ABx	483:485	arg1	treatment					487:495	ABx treatment	483:495	ABx treatment	483:495	Our results showed that ABx treatment can induce gut microbiota dysbiosis and intestinal inflammation in mice.					
35376973	7	5	theme	transforming	1318:1329	arg1	TGF-β1					1349:1354	TGF-β1	1349:1354	TGF-β1	1349:1354	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	5	theme	transforming	1318:1329	arg1	β1					1345:1346	the anti-inflammatory mediator transforming growth factor β1	1287:1346	the anti-inflammatory mediator transforming growth factor β1 (TGF-β1)	1287:1355	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	4	6	theme	ITF	597:599	arg1	supplementation					601:615	ITF supplementation	597:615	ITF supplementation	597:615	After 4 weeks of recovery, ITF supplementation restored the composition of the intestinal microbial community.					
35376973	6	7	from	recovery	978:985	arg1	propria					1001:1007	the lamina propria	990:1007	the lamina propria (LP)	990:1012	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	6	7	from	recovery	978:985	arg1	LP					1010:1011	LP	1010:1011	LP	1010:1011	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	7	8	theme	anti-inflammatory	1291:1307	arg1	TGF-β1					1349:1354	TGF-β1	1349:1354	TGF-β1	1349:1354	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	8	theme	anti-inflammatory	1291:1307	arg1	β1					1345:1346	the anti-inflammatory mediator transforming growth factor β1	1287:1346	the anti-inflammatory mediator transforming growth factor β1 (TGF-β1)	1287:1355	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	3	9	theme	gut	508:510	arg1	dysbiosis					523:531	gut microbiota dysbiosis	508:531	gut microbiota dysbiosis	508:531	Our results showed that ABx treatment can induce gut microbiota dysbiosis and intestinal inflammation in mice.					
35376973	8	10	theme	ITFs	1593:1596	arg1	influence					1580:1588	the influence	1576:1588	the influence of ITFs on the host's intestinal status	1576:1628	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	8	10	theme	ITFs	1593:1596	arg1	beneficial					1644:1653	beneficial	1644:1653	beneficial	1644:1653	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	7	11	theme	-17A	1514:1517	arg1	secretion					1456:1464	the secretion	1452:1464	the secretion of the proinflammatory cytokine interleukin (IL)-17A	1452:1517	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	8	12	from	beneficial	1644:1653	arg1	context					1662:1668	the context	1658:1668	the context of ABx-induced biological disorder	1658:1703	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	5	13	theme	diamine	809:815	arg1	oxidase					817:823	diamine oxidase	809:823	diamine oxidase (DAO) activity	809:838	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	5	13	theme	diamine	809:815	arg1	DAO					826:828	DAO	826:828	DAO	826:828	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	6	14	theme	ITF	910:912	arg1	supplementation					914:928	ITF supplementation	910:928	ITF supplementation	910:928	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	10	15	theme	inflammation	1928:1939	arg1	recovery					1896:1903	the recovery	1892:1903	the recovery of ABx-induced colonic inflammation	1892:1939	• ITFs delayed the recovery of ABx-induced colonic inflammation.					
35376973	4	16	theme	recovery	587:594	arg1	4 weeks					576:582	4 weeks	576:582	4 weeks of recovery	576:594	After 4 weeks of recovery, ITF supplementation restored the composition of the intestinal microbial community.					
35376973	3	17	theme	intestinal	537:546	arg1	inflammation					548:559	intestinal inflammation	537:559	intestinal inflammation	537:559	Our results showed that ABx treatment can induce gut microbiota dysbiosis and intestinal inflammation in mice.					
35376973	1	18	theme	intestinal	196:205	arg1	function					214:221	the intestinal immune function	192:221	the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	192:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	7	19	theme	interleukin	1498:1508	arg1	-17A					1514:1517	the proinflammatory cytokine interleukin (IL)-17A	1469:1517	the proinflammatory cytokine interleukin (IL)-17A	1469:1517	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	9	20	theme	•	1805:1805	arg1	ITFs					1807:1810	• ITFs	1805:1810	• ITFs	1805:1810	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	4	21	theme	microbial	660:668	arg1	community					670:678	the intestinal microbial community	645:678	the intestinal microbial community	645:678	After 4 weeks of recovery, ITF supplementation restored the composition of the intestinal microbial community.					
35376973	7	22	theme	proinflammatory	1473:1487	arg1	IL					1511:1512	IL	1511:1512	IL	1511:1512	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	22	theme	proinflammatory	1473:1487	arg1	interleukin					1498:1508	the proinflammatory cytokine interleukin	1469:1508	the proinflammatory cytokine interleukin (IL)-17A	1469:1517	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	1	23	from	function	214:221	arg1	context					230:236	the context	226:236	the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	226:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	5	24	from	activity	831:838	arg1	serum					890:894	serum	890:894	serum	890:894	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	7	25	theme	inducible	1164:1172	arg1	synthase					1187:1194	inducible nitric oxide synthase	1164:1194	inducible nitric oxide synthase (iNOS)	1164:1201	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	25	theme	inducible	1164:1172	arg1	iNOS					1197:1200	iNOS	1197:1200	iNOS	1197:1200	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	5	26	theme	lipopolysaccharide	854:871	arg1	content					879:885	increased lipopolysaccharide (LPS) content	844:885	increased lipopolysaccharide (LPS) content in serum	844:894	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	5	27	theme	ITF	726:728	arg1	supplementation					730:744	ITF supplementation	726:744	ITF supplementation	726:744	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	9	28	theme	microbial	1844:1852	arg1	composition					1864:1874	microbial community composition	1844:1874	microbial community composition	1844:1874	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	10	29	theme	•	1877:1877	arg1	ITFs					1879:1882	• ITFs	1877:1882	• ITFs	1877:1882	• ITFs delayed the recovery of ABx-induced colonic inflammation.					
35376973	0	30	theme	mice	91:94	arg1	function					60:67	the intestinal immune function	38:67	the intestinal immune function of antibiotic-treated mice	38:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	1	31	from	effect	130:135	arg1	function					214:221	the intestinal immune function	192:221	the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	192:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	6	32	theme	regulatory	942:951	arg1	cell					962:965	regulatory T (Treg) cell	942:965	regulatory T (Treg) cell	942:965	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	9	33	theme	composition	1864:1874	arg1	recovery					1832:1839	the recovery	1828:1839	the recovery of microbial community composition	1828:1874	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	7	34	theme	proinflammatory	1129:1143	arg1	genes					1145:1149	certain proinflammatory genes	1121:1149	certain proinflammatory genes	1121:1149	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	34	theme	proinflammatory	1129:1143	arg1	α					1230:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α	1164:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α)	1164:1238	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	8	35	theme	biological	1685:1694	arg1	disorder					1696:1703	ABx-induced biological disorder	1673:1703	ABx-induced biological disorder	1673:1703	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	2	36	dep	mice	310:313	arg1	8-9 weeks					316:324	8-9 weeks	316:324	8-9 weeks of age	316:331	BALB/c mice (8-9 weeks of age) were treated with an ABx for 3 weeks and then allowed to recover spontaneously or with ITF supplementation (5%) for 4 weeks.					
35376973	6	37	theme	lamina	994:999	arg1	propria					1001:1007	the lamina propria	990:1007	the lamina propria (LP)	990:1012	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	6	37	theme	lamina	994:999	arg1	LP					1010:1011	LP	1010:1011	LP	1010:1011	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	7	38	theme	relative	1098:1105	arg1	expression					1107:1116	the relative expression	1094:1116	the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon	1094:1252	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	1	39	theme	cocktail	277:284	arg1	treatment					292:300	antibiotic cocktail (ABx) treatment	266:300	antibiotic cocktail (ABx) treatment	266:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	8	40	from	influence	1580:1588	arg1	status					1623:1628	the host's intestinal status	1601:1628	the host's intestinal status	1601:1628	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	0	41	theme	fructans	26:33	arg1	effect					4:9	The effect	0:9	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice	0:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	7	42	theme	A	1417:1417	arg1	secretion					1379:1387	the secretion	1375:1387	the secretion of secretory immunoglobulin A (SIgA) in the colon	1375:1437	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	43	theme	factor	1223:1228	arg1	α					1230:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α	1164:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α)	1164:1238	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	43	theme	factor	1223:1228	arg1	Tnf-α					1233:1237	Tnf-α	1233:1237	Tnf-α	1233:1237	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	0	44	theme	immune	53:58	arg1	function					60:67	the intestinal immune function	38:67	the intestinal immune function of antibiotic-treated mice	38:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	12	45	theme	Treg	2022:2025	arg1	cells					2033:2037	Treg and B cells	2022:2037	cells	2033:2037	• ITFs delayed the recovery of Treg and B cells in the LP.					
35376973	7	46	theme	ITF	1064:1066	arg1	supplementation					1068:1082	ITF supplementation	1064:1082	ITF supplementation	1064:1082	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	47	theme	secretory	1392:1400	arg1	SIgA					1420:1423	SIgA	1420:1423	SIgA	1420:1423	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	47	theme	secretory	1392:1400	arg1	A					1417:1417	secretory immunoglobulin A	1392:1417	secretory immunoglobulin A (SIgA)	1392:1424	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	48	theme	tumour	1207:1212	arg1	factor					1223:1228	tumour necrosis factor	1207:1228	tumour necrosis factor	1207:1228	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	10	49	theme	ABx-induced	1908:1918	arg1	inflammation					1928:1939	ABx-induced colonic inflammation	1908:1939	ABx-induced colonic inflammation	1908:1939	• ITFs delayed the recovery of ABx-induced colonic inflammation.					
35376973	12	50	theme	•	1991:1991	arg1	ITFs					1993:1996	• ITFs	1991:1996	• ITFs	1991:1996	• ITFs delayed the recovery of Treg and B cells in the LP.					
35376973	1	51	theme	immune	207:212	arg1	function					214:221	the intestinal immune function	192:221	the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	192:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	8	52	theme	disorder	1696:1703	arg1	context					1662:1668	the context	1658:1668	the context of ABx-induced biological disorder	1658:1703	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	6	53	theme	cell	973:976	arg1	recovery					978:985	the regulatory T (Treg) cell and B cell recovery	938:985	the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP)	938:1012	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	0	54	theme	intestinal	42:51	arg1	function					60:67	the intestinal immune function	38:67	the intestinal immune function of antibiotic-treated mice	38:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	7	55	theme	spontaneous	1042:1052	arg1	recovery					1054:1061	spontaneous recovery	1042:1061	spontaneous recovery	1042:1061	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	2	56	theme	age	329:331	arg1	8-9 weeks					316:324	8-9 weeks	316:324	8-9 weeks of age	316:331	BALB/c mice (8-9 weeks of age) were treated with an ABx for 3 weeks and then allowed to recover spontaneously or with ITF supplementation (5%) for 4 weeks.					
35376973	7	57	theme	oxide	1181:1185	arg1	synthase					1187:1194	inducible nitric oxide synthase	1164:1194	inducible nitric oxide synthase (iNOS)	1164:1201	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	57	theme	oxide	1181:1185	arg1	iNOS					1197:1200	iNOS	1197:1200	iNOS	1197:1200	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	9	58	theme	findings	1741:1748	arg1	significance					1719:1730	the significance	1715:1730	the significance of these findings	1715:1748	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	1	59	theme	dysbiosis	241:249	arg1	context					230:236	the context	226:236	the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	226:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	7	60	theme	β1	1345:1346	arg1	secretion					1274:1282	the secretion	1270:1282	the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum	1270:1364	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	1	61	theme	inulin-type	161:171	arg1	ITFs					183:186	ITFs	183:186	ITFs	183:186	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	1	61	theme	inulin-type	161:171	arg1	fructans					173:180	inulin-type fructans	161:180	inulin-type fructans (ITFs)	161:187	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	11	62	theme	SIgA	1985:1988	arg1	secretion					1961:1969	the secretion	1957:1969	the secretion of TGF-β1 and SIgA	1957:1988	• ITFs reduced the secretion of TGF-β1 and SIgA.					
35376973	7	63	theme	growth	1331:1336	arg1	TGF-β1					1349:1354	TGF-β1	1349:1354	TGF-β1	1349:1354	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	63	theme	growth	1331:1336	arg1	β1					1345:1346	the anti-inflammatory mediator transforming growth factor β1	1287:1346	the anti-inflammatory mediator transforming growth factor β1 (TGF-β1)	1287:1355	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	11	64	theme	TGF-β1	1974:1979	arg1	secretion					1961:1969	the secretion	1957:1969	the secretion of TGF-β1 and SIgA	1957:1988	• ITFs reduced the secretion of TGF-β1 and SIgA.					
35376973	7	65	theme	mediator	1309:1316	arg1	TGF-β1					1349:1354	TGF-β1	1349:1354	TGF-β1	1349:1354	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	65	theme	mediator	1309:1316	arg1	β1					1345:1346	the anti-inflammatory mediator transforming growth factor β1	1287:1346	the anti-inflammatory mediator transforming growth factor β1 (TGF-β1)	1287:1355	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	9	66	theme	advanced	1776:1783	arg1	studies					1785:1791	advanced studies KEY POINTS	1776:1802	advanced studies KEY POINTS	1776:1802	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	9	67	theme	KEY	1793:1795	arg1	POINTS					1797:1802	KEY POINTS	1793:1802	advanced studies KEY POINTS	1776:1802	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	5	68	theme	oxidase	817:823	arg1	activity					831:838	diamine oxidase (DAO) activity	809:838	diamine oxidase (DAO) activity	809:838	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	7	69	theme	cytokine	1489:1496	arg1	IL					1511:1512	IL	1511:1512	IL	1511:1512	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	69	theme	cytokine	1489:1496	arg1	interleukin					1498:1508	the proinflammatory cytokine interleukin	1469:1508	the proinflammatory cytokine interleukin (IL)-17A	1469:1517	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	3	70	theme	microbiota	512:521	arg1	dysbiosis					523:531	gut microbiota dysbiosis	508:531	gut microbiota dysbiosis	508:531	Our results showed that ABx treatment can induce gut microbiota dysbiosis and intestinal inflammation in mice.					
35376973	11	71	theme	•	1942:1942	arg1	ITFs					1944:1947	• ITFs	1942:1947	• ITFs	1942:1947	• ITFs reduced the secretion of TGF-β1 and SIgA.					
35376973	8	72	from	context	1662:1668	arg1	influence					1580:1588	the influence	1576:1588	the influence of ITFs on the host's intestinal status	1576:1628	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	8	72	from	context	1662:1668	arg1	beneficial					1644:1653	beneficial	1644:1653	beneficial	1644:1653	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	8	73	theme	intestinal	1612:1621	arg1	status					1623:1628	the host's intestinal status	1601:1628	the host's intestinal status	1601:1628	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	6	74	theme	B	971:971	arg1	cell					973:976	B cell	971:976	B cell	971:976	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	4	75	theme	community	670:678	arg1	composition					630:640	the composition	626:640	the composition of the intestinal microbial community	626:678	After 4 weeks of recovery, ITF supplementation restored the composition of the intestinal microbial community.					
35376973	5	76	theme	spontaneous	704:714	arg1	recovery					716:723	spontaneous recovery	704:723	spontaneous recovery	704:723	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	5	77	theme	increased	844:852	arg1	content					879:885	increased lipopolysaccharide (LPS) content	844:885	increased lipopolysaccharide (LPS) content in serum	844:894	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	6	78	theme	cell	962:965	arg1	recovery					978:985	the regulatory T (Treg) cell and B cell recovery	938:985	the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP)	938:1012	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	0	79	theme	antibiotic-treated	72:89	arg1	mice					91:94	antibiotic-treated mice	72:94	antibiotic-treated mice	72:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	5	80	from	recovery	767:774	arg1	intestine					783:791	the intestine	779:791	the intestine	779:791	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	1	81	with	supplementation	140:154	arg1	ITFs					183:186	ITFs	183:186	ITFs	183:186	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	1	81	with	supplementation	140:154	arg1	fructans					173:180	inulin-type fructans	161:180	inulin-type fructans (ITFs)	161:187	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	9	82	dep	studies	1785:1791	arg1	POINTS					1797:1802	KEY POINTS	1793:1802	advanced studies KEY POINTS	1776:1802	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	1	83	theme	supplementation	140:154	arg1	effect					130:135	the effect	126:135	the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment	126:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	6	84	theme	Treg	956:959	arg1	cell					962:965	regulatory T (Treg) cell	942:965	regulatory T (Treg) cell	942:965	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	0	85	from	effect	4:9	arg1	function					60:67	the intestinal immune function	38:67	the intestinal immune function of antibiotic-treated mice	38:94	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	7	86	theme	genes	1145:1149	arg1	expression					1107:1116	the relative expression	1094:1116	the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon	1094:1252	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	6	87	theme	T	953:953	arg1	cell					962:965	regulatory T (Treg) cell	942:965	regulatory T (Treg) cell	942:965	In addition, ITF supplementation delayed the regulatory T (Treg) cell and B cell recovery in the lamina propria (LP).					
35376973	9	88	theme	community	1854:1862	arg1	composition					1864:1874	microbial community composition	1844:1874	microbial community composition	1844:1874	However, the significance of these findings needs to be determined by advanced studies KEY POINTS: • ITFs did not promote the recovery of microbial community composition.					
35376973	7	89	theme	certain	1121:1127	arg1	genes					1145:1149	certain proinflammatory genes	1121:1149	certain proinflammatory genes	1121:1149	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	89	theme	certain	1121:1127	arg1	α					1230:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α	1164:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α)	1164:1238	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	90	from	expression	1107:1116	arg1	colon					1248:1252	the colon	1244:1252	the colon	1244:1252	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	8	91	theme	ABx-induced	1673:1683	arg1	disorder					1696:1703	ABx-induced biological disorder	1673:1703	ABx-induced biological disorder	1673:1703	In conclusion, these data supported the hypothesis that the influence of ITFs on the host's intestinal status is not always beneficial in the context of ABx-induced biological disorder.					
35376973	0	92	theme	inulin-type	14:24	arg1	fructans					26:33	inulin-type fructans	14:33	inulin-type fructans	14:33	The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.					
35376973	1	93	theme	antibiotic	266:275	arg1	treatment					292:300	antibiotic cocktail (ABx) treatment	266:300	antibiotic cocktail (ABx) treatment	266:300	This study aimed to evaluate the effect of supplementation with inulin-type fructans (ITFs) on the intestinal immune function in the context of dysbiosis resulting from antibiotic cocktail (ABx) treatment.					
35376973	5	94	from	content	879:885	arg1	serum					890:894	serum	890:894	serum	890:894	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	12	95	theme	cells	2033:2037	arg1	recovery					2010:2017	the recovery	2006:2017	the recovery of Treg and B cells in the LP	2006:2047	• ITFs delayed the recovery of Treg and B cells in the LP.					
35376973	7	96	from	secretion	1274:1282	arg1	serum					1360:1364	serum	1360:1364	serum	1360:1364	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	97	theme	necrosis	1214:1221	arg1	factor					1223:1228	tumour necrosis factor	1207:1228	tumour necrosis factor	1207:1228	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	2	98	theme	ITF	421:423	arg1	%					443:443	5%	442:443	5%	442:443	BALB/c mice (8-9 weeks of age) were treated with an ABx for 3 weeks and then allowed to recover spontaneously or with ITF supplementation (5%) for 4 weeks.					
35376973	2	98	theme	ITF	421:423	arg1	supplementation					425:439	ITF supplementation	421:439	ITF supplementation (5%) for 4 weeks	421:456	BALB/c mice (8-9 weeks of age) were treated with an ABx for 3 weeks and then allowed to recover spontaneously or with ITF supplementation (5%) for 4 weeks.					
35376973	5	99	theme	inflammation	754:765	arg1	recovery					767:774	inflammation recovery	754:774	inflammation recovery in the intestine	754:791	However, compared with spontaneous recovery, ITF supplementation delayed inflammation recovery in the intestine and upregulated diamine oxidase (DAO) activity and increased lipopolysaccharide (LPS) content in serum.					
35376973	7	100	theme	immunoglobulin	1402:1415	arg1	SIgA					1420:1423	SIgA	1420:1423	SIgA	1420:1423	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	100	theme	immunoglobulin	1402:1415	arg1	A					1417:1417	secretory immunoglobulin A	1392:1417	secretory immunoglobulin A (SIgA)	1392:1424	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	2	101	theme	BALB/c	303:308	arg1	mice					310:313	BALB/c mice	303:313	BALB/c mice (8-9 weeks of age)	303:332	BALB/c mice (8-9 weeks of age) were treated with an ABx for 3 weeks and then allowed to recover spontaneously or with ITF supplementation (5%) for 4 weeks.					
35376973	12	102	from	recovery	2010:2017	arg1	LP					2046:2047	the LP	2042:2047	the LP	2042:2047	• ITFs delayed the recovery of Treg and B cells in the LP.					
35376973	7	103	from	secretion	1379:1387	arg1	colon					1433:1437	the colon	1429:1437	the colon	1429:1437	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	104	theme	synthase	1187:1194	arg1	α					1230:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α	1164:1230	inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α)	1164:1238	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	7	104	theme	synthase	1187:1194	arg1	Tnf-α					1233:1237	Tnf-α	1233:1237	Tnf-α	1233:1237	Furthermore, compared with spontaneous recovery, ITF supplementation inhibited the relative expression of certain proinflammatory genes, such as for inducible nitric oxide synthase (iNOS) and tumour necrosis factor α (Tnf-α), in the colon, but it reduced the secretion of the anti-inflammatory mediator transforming growth factor β1 (TGF-β1) in serum, reduced the secretion of secretory immunoglobulin A (SIgA) in the colon and promoted the secretion of the proinflammatory cytokine interleukin (IL)-17A.					
35376973	4	105	theme	intestinal	649:658	arg1	community					670:678	the intestinal microbial community	645:678	the intestinal microbial community	645:678	After 4 weeks of recovery, ITF supplementation restored the composition of the intestinal microbial community.					
36327703	10	0	with	consistent	1727:1736	arg1	response					1765:1772	an early foreign body response	1743:1772	an early foreign body response	1743:1772	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	7	1	theme	response	1215:1222	arg1	P < 0.001					1234:1242	P < 0.001	1234:1242	P < 0.001	1234:1242	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	7	1	theme	response	1215:1222	arg1	in vitro					1224:1231	a stronger proinflammatory, M1-like macrophage response in vitro	1168:1231	a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001)	1168:1243	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	10	2	theme	potato	1806:1811	arg1	crystals					1820:1827	potato starch crystals	1806:1827	potato starch crystals	1806:1827	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	3	theme	such	1841:1844	arg1	cell					1846:1849	no such cell or connective tissue deposition	1838:1881	cell	1846:1849	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	7	4	theme	proinflammatory	1179:1193	arg1	P < 0.001					1234:1242	P < 0.001	1234:1242	P < 0.001	1234:1242	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	7	4	theme	proinflammatory	1179:1193	arg1	in vitro					1224:1231	a stronger proinflammatory, M1-like macrophage response in vitro	1168:1231	a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001)	1168:1243	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	1	5	theme	postoperative	180:192	arg1	complications					194:206	intraoperative and postoperative complications	161:206	intraoperative and postoperative complications	161:206	INTRODUCTION Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications.					
36327703	8	6	theme	in vivo	1337:1343	arg1	site					1354:1357	the in vivo surgical site	1333:1357	the in vivo surgical site	1333:1357	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	10	7	theme	Collagen	1673:1680	arg1	deposition					1682:1691	Collagen deposition	1673:1691	Collagen deposition	1673:1691	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	8	theme	tissue	1865:1870	arg1	deposition					1872:1881	no such cell or connective tissue deposition	1838:1881	deposition	1872:1881	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	5	9	theme	high	909:912	arg1	resorbable					935:944	high crystallinity/slowly resorbable	909:944	high crystallinity/slowly resorbable	909:944	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	6	10	theme	degradation	1021:1031	arg1	products					1033:1040	their degradation products	1015:1040	their degradation products	1015:1040	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	8	11	theme	site	1354:1357	arg1	examination					1318:1328	Histologic examination	1307:1328	Histologic examination of the in vivo surgical site	1307:1357	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	5	12	theme	extracellular	875:887	arg1	matrix					889:894	extracellular matrix	875:894	extracellular matrix (UBM-ECM)	875:904	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	12	theme	extracellular	875:887	arg1	UBM-ECM					897:903	UBM-ECM	897:903	UBM-ECM	897:903	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	8	13	located	present	1478:1484	arg2	PerClot					1441:1447	PerClot	1441:1447	PerClot	1441:1447	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	13	located	present	1478:1484	arg1	28 d					1489:1492	28 d	1489:1492	28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining	1489:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	13	located	present	1478:1484	arg2	starch					1460:1465	potato starch	1453:1465	potato starch	1453:1465	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	6	14	dep	RESULTS	985:991	arg1	articles					1002:1009	All test articles	993:1009	All test articles	993:1009	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	6	14	dep	RESULTS	985:991	arg1	products					1033:1040	their degradation products	1015:1040	their degradation products	1015:1040	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	10	15	theme	cell	1709:1712	arg1	accumulation					1714:1725	mononuclear cell accumulation	1697:1725	mononuclear cell accumulation	1697:1725	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	2	16	theme	coagulation	243:253	arg1	promotion					224:232	promotion	224:232	promotion of rapid coagulation, resorption, and biocompatibility	224:287	In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes.					
36327703	8	17	theme	Histologic	1307:1316	arg1	examination					1318:1328	Histologic examination	1307:1328	Histologic examination of the in vivo surgical site	1307:1357	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	6	18	theme	test	997:1000	arg1	articles					1002:1009	All test articles	993:1009	All test articles	993:1009	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	3	19	theme	polysaccharide	334:347	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	19	theme	polysaccharide	334:347	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	8	20	theme	complete	1377:1384	arg1	degradation					1386:1396	the almost complete degradation	1366:1396	the almost complete degradation of Arista	1366:1406	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	7	21	dep	proinflammatory	1179:1193	arg1	stronger					1170:1177	stronger	1170:1177	stronger	1170:1177	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	7	21	dep	proinflammatory	1179:1193	arg1	M1-like					1196:1202	M1-like	1196:1202	M1-like	1196:1202	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	3	22	theme	Plant	315:319	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	22	theme	Plant	315:319	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	8	23	theme	light	1536:1540	arg1	microscopy					1542:1551	polarized light microscopy	1526:1551	polarized light microscopy	1526:1551	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	10	24	theme	Arista	1908:1913	arg1	Arista					1908:1913	Arista	1908:1913	Arista	1908:1913	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	24	theme	Arista	1908:1913	arg1	placement					1926:1934	UBM-ECM placement	1918:1934	UBM-ECM placement	1918:1934	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	24	theme	Arista	1908:1913	arg1	site					1900:1903	the site	1896:1903	the site of Arista or UBM-ECM placement	1896:1934	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	6	25	theme	cell	1086:1089	arg1	viability					1091:1099	cell viability	1086:1099	cell viability	1086:1099	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	3	26	theme	effective	370:378	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	26	theme	effective	370:378	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	2	27	theme	resorption	256:265	arg1	promotion					224:232	promotion	224:232	promotion of rapid coagulation, resorption, and biocompatibility	224:287	In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes.					
36327703	4	28	theme	purified/hydrolyzed	537:555	arg1	powder					564:569	a purified/hydrolyzed starch powder	535:569	a purified/hydrolyzed starch powder that is rapidly resorbed in vivo	535:602	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	4	28	theme	purified/hydrolyzed	537:555	arg1	Arista					525:530	Arista	525:530	Arista	525:530	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	3	29	theme	starch-based	321:332	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	29	theme	starch-based	321:332	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	1	30	theme	intraoperative	161:174	arg1	complications					194:206	intraoperative and postoperative complications	161:206	intraoperative and postoperative complications	161:206	INTRODUCTION Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications.					
36327703	3	31	theme	hemostatic	396:405	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	31	theme	hemostatic	396:405	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	0	32	theme	Hemostat	79:86	arg1	Powders					88:94	Two Starch-Based Hemostat Powders	62:94	Two Starch-Based Hemostat Powders	62:94	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	10	33	theme	early	1746:1750	arg1	response					1765:1772	an early foreign body response	1743:1772	an early foreign body response	1743:1772	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	0	34	theme	Resorption	27:36	arg1	Study					14:18	A Comparative Study	0:18	A Comparative Study of the Resorption	0:36	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	0	34	theme	Resorption	27:36	arg1	Response					49:56	Immune Response	42:56	Immune Response for Two Starch-Based Hemostat Powders	42:94	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	6	35	theme	bone-marrow	1127:1137	arg1	macrophages					1139:1149	bone-marrow macrophages	1127:1149	bone-marrow macrophages	1127:1149	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	5	36	theme	urinary	859:865	arg1	starch					848:853	potato starch	841:853	potato starch	841:853	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	36	theme	urinary	859:865	arg1	bladder					867:873	urinary bladder	859:873	urinary bladder	859:873	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	36	theme	urinary	859:865	arg1	controls					961:968	prohealing controls	950:968	prohealing controls	950:968	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	1	37	theme	INTRODUCTION	97:108	arg1	hemostats					117:125	INTRODUCTION Powder hemostats	97:125	INTRODUCTION Powder hemostats	97:125	INTRODUCTION Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications.					
36327703	10	38	theme	body	1760:1763	arg1	response					1765:1772	an early foreign body response	1743:1772	an early foreign body response	1743:1772	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	39	theme	UBM-ECM	1918:1924	arg1	placement					1926:1934	UBM-ECM placement	1918:1934	UBM-ECM placement	1918:1934	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	4	40	theme	starch	557:562	arg1	powder					564:569	a purified/hydrolyzed starch powder	535:569	a purified/hydrolyzed starch powder that is rapidly resorbed in vivo	535:602	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	4	40	theme	starch	557:562	arg1	Arista					525:530	Arista	525:530	Arista	525:530	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	8	41	with	identifiable	1508:1519	arg1	microscopy					1542:1551	polarized light microscopy	1526:1551	polarized light microscopy	1526:1551	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	41	with	identifiable	1508:1519	arg1	staining					1584:1591	periodic acid Schiff (PAS) staining	1557:1591	periodic acid Schiff (PAS) staining	1557:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	4	42	theme	crystalline	665:675	arg1	form					677:680	a crystalline form	663:680	a crystalline form	663:680	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	7	43	theme	source	1287:1292	arg1	composition					1294:1304	source composition	1287:1304	source composition	1287:1304	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	7	44	theme	macrophage	1204:1213	arg1	P < 0.001					1234:1242	P < 0.001	1234:1242	P < 0.001	1234:1242	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	7	44	theme	macrophage	1204:1213	arg1	in vitro					1224:1231	a stronger proinflammatory, M1-like macrophage response in vitro	1168:1231	a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001)	1168:1243	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	10	45	theme	starch	1813:1818	arg1	crystals					1820:1827	potato starch crystals	1806:1827	potato starch crystals	1806:1827	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	8	46	theme	acid	1566:1569	arg1	staining					1584:1591	periodic acid Schiff (PAS) staining	1557:1591	periodic acid Schiff (PAS) staining	1557:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	4	47	theme	slow	627:630	arg1	resorption					632:641	slow resorption	627:641	slow resorption	627:641	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	5	48	theme	present	712:718	arg1	study					720:724	the present study	708:724	the present study	708:724	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	49	dep	starch	848:853	arg1	matrix					889:894	extracellular matrix	875:894	extracellular matrix (UBM-ECM)	875:904	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	49	dep	starch	848:853	arg1	UBM-ECM					897:903	UBM-ECM	897:903	UBM-ECM	897:903	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	2	50	theme	desirable	293:301	arg1	attributes					303:312	desirable attributes	293:312	desirable attributes	293:312	In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes.					
36327703	5	51	theme	cellular	743:750	arg1	response					752:759	the cellular response	739:759	the cellular response to the hemostatic agents PerClot and Arista	739:803	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	10	52	theme	connective	1854:1863	arg1	deposition					1872:1881	no such cell or connective tissue deposition	1838:1881	deposition	1872:1881	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	8	53	from	28 d	1489:1492	arg1	present					1478:1484	present	1478:1484	present	1478:1484	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	54	theme	identifiable	1508:1519	arg1	crystals					1499:1506	crystals	1499:1506	crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining	1499:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	5	55	theme	prohealing	950:959	arg1	starch					848:853	potato starch	841:853	potato starch	841:853	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	55	theme	prohealing	950:959	arg1	bladder					867:873	urinary bladder	859:873	urinary bladder	859:873	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	55	theme	prohealing	950:959	arg1	controls					961:968	prohealing controls	950:968	prohealing controls	950:968	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	9	56	theme	Macrophage	1594:1603	arg1	in vivo					1615:1621	Macrophage phenotype in vivo	1594:1621	Macrophage phenotype in vivo	1594:1621	Macrophage phenotype in vivo showed no differences between PerClot and Arista.					
36327703	8	57	theme	surgical	1345:1352	arg1	site					1354:1357	the in vivo surgical site	1333:1357	the in vivo surgical site	1333:1357	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	7	58	from	differences	1272:1282	arg1	composition					1294:1304	source composition	1287:1304	source composition	1287:1304	PerClot induced a stronger proinflammatory, M1-like macrophage response in vitro (P < 0.001) than Arista, likely due to differences in source composition.					
36327703	10	59	theme	mononuclear	1697:1707	arg1	accumulation					1714:1725	mononuclear cell accumulation	1697:1725	mononuclear cell accumulation	1697:1725	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	8	60	with	28 d	1489:1492	arg1	crystals					1499:1506	crystals	1499:1506	crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining	1499:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	2	61	theme	rapid	237:241	arg1	coagulation					243:253	rapid coagulation	237:253	rapid coagulation	237:253	In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes.					
36327703	1	62	theme	Powder	110:115	arg1	hemostats					117:125	INTRODUCTION Powder hemostats	97:125	INTRODUCTION Powder hemostats	97:125	INTRODUCTION Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications.					
36327703	3	63	theme	hemostat	349:356	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	63	theme	hemostat	349:356	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	2	64	theme	biocompatibility	272:287	arg1	promotion					224:232	promotion	224:232	promotion of rapid coagulation, resorption, and biocompatibility	224:287	In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes.					
36327703	5	65	dep	agents	779:784	arg1	PerClot					786:792	PerClot	786:792	PerClot	786:792	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	65	dep	agents	779:784	arg1	agents					779:784	the hemostatic agents PerClot and Arista	764:803	the hemostatic agents PerClot and Arista	764:803	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	65	dep	agents	779:784	arg1	Arista					798:803	Arista	798:803	Arista	798:803	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	8	66	theme	periodic	1557:1564	arg1	staining					1584:1591	periodic acid Schiff (PAS) staining	1557:1591	periodic acid Schiff (PAS) staining	1557:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	5	67	theme	crystallinity/slowly	914:933	arg1	resorbable					935:944	high crystallinity/slowly resorbable	909:944	high crystallinity/slowly resorbable	909:944	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	8	68	theme	Schiff	1571:1576	arg1	staining					1584:1591	periodic acid Schiff (PAS) staining	1557:1591	periodic acid Schiff (PAS) staining	1557:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	69	theme	Arista	1401:1406	arg1	degradation					1386:1396	the almost complete degradation	1366:1396	the almost complete degradation of Arista	1366:1406	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	0	70	theme	Starch-Based	66:77	arg1	Powders					88:94	Two Starch-Based Hemostat Powders	62:94	Two Starch-Based Hemostat Powders	62:94	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	8	71	theme	PAS	1579:1581	arg1	staining					1584:1591	periodic acid Schiff (PAS) staining	1557:1591	periodic acid Schiff (PAS) staining	1557:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	5	72	theme	hemostatic	768:777	arg1	PerClot					786:792	PerClot	786:792	PerClot	786:792	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	72	theme	hemostatic	768:777	arg1	agents					779:784	the hemostatic agents PerClot and Arista	764:803	the hemostatic agents PerClot and Arista	764:803	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	72	theme	hemostatic	768:777	arg1	Arista					798:803	Arista	798:803	Arista	798:803	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	9	73	theme	phenotype	1605:1613	arg1	in vivo					1615:1621	Macrophage phenotype in vivo	1594:1621	Macrophage phenotype in vivo	1594:1621	Macrophage phenotype in vivo showed no differences between PerClot and Arista.					
36327703	6	74	theme	cytocompatible	1047:1060	arg1	in vitro					1062:1069	cytocompatible in vitro	1047:1069	cytocompatible in vitro	1047:1069	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	1	75	dep	valuable	131:138	arg1	adjuncts					140:147	adjuncts	140:147	adjuncts to minimize intraoperative and postoperative complications	140:206	INTRODUCTION Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications.					
36327703	3	76	theme	used	391:394	arg1	powders					358:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders	315:364	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	3	76	theme	used	391:394	arg1	agents					407:412	effective and widely used hemostatic agents	370:412	effective and widely used hemostatic agents	370:412	Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in vivo degradability.					
36327703	0	77	theme	Comparative	2:12	arg1	Study					14:18	A Comparative Study	0:18	A Comparative Study of the Resorption	0:36	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	6	78	theme	macrophages	1139:1149	arg1	activity					1115:1122	metabolic activity	1105:1122	metabolic activity	1105:1122	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	6	78	theme	macrophages	1139:1149	arg1	viability					1091:1099	cell viability	1086:1099	cell viability	1086:1099	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	10	79	theme	consistent	1727:1736	arg1	deposition					1682:1691	Collagen deposition	1673:1691	Collagen deposition	1673:1691	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	5	80	used	used	836:839	arg2	we					727:728	we	727:728	we	727:728	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	8	81	attach	present	1478:1484	arg2	PerClot					1441:1447	PerClot	1441:1447	PerClot	1441:1447	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	81	attach	present	1478:1484	arg1	28 d					1489:1492	28 d	1489:1492	28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining	1489:1591	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	8	81	attach	present	1478:1484	arg2	starch					1460:1465	potato starch	1453:1465	potato starch	1453:1465	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	6	82	theme	metabolic	1105:1113	arg1	activity					1115:1122	metabolic activity	1105:1122	metabolic activity	1105:1122	RESULTS All test articles and their degradation products were cytocompatible in vitro as measured by cell viability and metabolic activity of bone-marrow macrophages.					
36327703	10	83	theme	placement	1926:1934	arg1	Arista					1908:1913	Arista	1908:1913	Arista	1908:1913	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	83	theme	placement	1926:1934	arg1	placement					1926:1934	UBM-ECM placement	1918:1934	UBM-ECM placement	1918:1934	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	10	83	theme	placement	1926:1934	arg1	site					1900:1903	the site	1896:1903	the site of Arista or UBM-ECM placement	1896:1934	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	8	84	theme	potato	1453:1458	arg1	starch					1460:1465	potato starch	1453:1465	potato starch	1453:1465	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	10	85	theme	foreign	1752:1758	arg1	response					1765:1772	an early foreign body response	1743:1772	an early foreign body response	1743:1772	Collagen deposition and mononuclear cell accumulation consistent with an early foreign body response were present around PerClot and potato starch crystals, whereas no such cell or connective tissue deposition was noted at the site of Arista or UBM-ECM placement.					
36327703	0	86	theme	Immune	42:47	arg1	Response					49:56	Immune Response	42:56	Immune Response for Two Starch-Based Hemostat Powders	42:94	A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders.					
36327703	5	87	dep	MATERIALS	683:691	arg1	compared					730:737	compared	730:737	compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo	730:829	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	87	dep	MATERIALS	683:691	arg1	used					836:839	used	836:839	used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively	836:982	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	8	88	theme	polarized	1526:1534	arg1	microscopy					1542:1551	polarized light microscopy	1526:1551	polarized light microscopy	1526:1551	Histologic examination of the in vivo surgical site showed the almost complete degradation of Arista after 12 h (day 0), whereas both PerClot and potato starch were still present at 28 d with crystals identifiable with polarized light microscopy and periodic acid Schiff (PAS) staining.					
36327703	4	89	theme	form	677:680	arg1	preservation					647:658	preservation	647:658	preservation	647:658	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	4	89	theme	form	677:680	arg1	resorption					632:641	slow resorption	627:641	slow resorption	627:641	For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.					
36327703	5	90	theme	potato	841:846	arg1	starch					848:853	potato starch	841:853	potato starch	841:853	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	90	theme	potato	841:846	arg1	bladder					867:873	urinary bladder	859:873	urinary bladder	859:873	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
36327703	5	90	theme	potato	841:846	arg1	controls					961:968	prohealing controls	950:968	prohealing controls	950:968	MATERIALS AND METHODS In the present study, we compared the cellular response to the hemostatic agents PerClot and Arista both in vitro and in vivo, and used potato starch and urinary bladder extracellular matrix (UBM-ECM) as high crystallinity/slowly resorbable and prohealing controls, respectively.					
37101209	7	0	theme	longer	1430:1435	arg1	colons					1437:1442	longer colons	1430:1442	longer colons	1430:1442	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	6	1	theme	16S	1053:1055	arg1	analysis					1068:1075	16S microbiome analysis	1053:1075	16S microbiome analysis	1053:1075	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	1	theme	16S	1053:1055	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	11	2	theme	colon	2264:2268	arg1	epithelium					2270:2279	the colon epithelium	2260:2279	the colon epithelium	2260:2279	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	1	3	theme	epithelial	282:291	arg1	barrier					293:299	the gut epithelial barrier	274:299	the gut epithelial barrier	274:299	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	6	4	theme	intake	1174:1179	arg1	impact					1157:1162	the impact	1153:1162	the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment	1153:1260	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	7	5	theme	intestinal	1378:1387	arg1	cells					1394:1398	intestinal stem cells	1378:1398	intestinal stem cells	1378:1398	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	10	6	theme	epithelium	2060:2069	arg1	effect					2075:2080	an effect	2072:2080	an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22	2072:2152	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	10	6	theme	epithelium	2060:2069	arg1	remodeling					2036:2045	a homeostatic remodeling	2022:2045	a homeostatic remodeling of the colon epithelium	2022:2069	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	6	7	theme	modified	1118:1125	arg1	models					1133:1138	genetically modified mouse models	1106:1138	genetically modified mouse models	1106:1138	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	7	theme	modified	1118:1125	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	11	8	theme	complex	2175:2181	arg1	kingdom					2189:2195	complex cross kingdom and cross cell type interactions	2175:2228	kingdom	2189:2195	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	6	9	theme	colonic	1188:1194	arg1	epithelium					1196:1205	the colonic epithelium	1184:1205	the colonic epithelium	1184:1205	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	1	10	theme	epithelial	221:230	arg1	cells					232:236	epithelial cells	221:236	epithelial cells	221:236	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	11	11	theme	type	2212:2215	arg1	interactions					2217:2228	complex cross kingdom and cross cell type interactions	2175:2228	interactions	2217:2228	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	5	12	theme	cellulose	917:925	arg1	cellulose					917:925	the insoluble fiber cellulose	897:925	the insoluble fiber cellulose	897:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	12	theme	cellulose	917:925	arg1	%					892:892	5%	891:892	5% of the insoluble fiber cellulose	891:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	9	13	theme	pivotal	1639:1645	arg1	role					1647:1650	the pivotal role	1635:1650	the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment	1635:1705	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	9	14	theme	system	1889:1894	arg1	crosstalk					1896:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	5	15	theme	METHODS	846:852	arg1	Mice					854:857	METHODS Mice	846:857	METHODS Mice	846:857	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	7	16	theme	diet	1310:1313	arg1	consumption					1288:1298	the consumption	1284:1298	the consumption of inulin diet	1284:1313	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	4	17	theme	inulin	691:696	arg1	consumption					698:708	inulin consumption	691:708	inulin consumption	691:708	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	1	18	theme	intestinal	144:153	arg1	cells					160:164	intestinal stem cells	144:164	intestinal stem cells	144:164	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	9	19	theme	T	1658:1658	arg1	lymphocytes					1660:1670	γδ T lymphocytes	1655:1670	γδ T lymphocytes	1655:1670	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	6	20	theme	local	1237:1241	arg1	compartment					1250:1260	the local immune compartment	1233:1260	the local immune compartment	1233:1260	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	5	21	theme	insoluble	901:909	arg1	cellulose					917:925	the insoluble fiber cellulose	897:925	the insoluble fiber cellulose	897:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	22	contain	containing	880:889	arg1	diet					875:878	a diet	873:878	a diet containing 5% of the insoluble fiber cellulose	873:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	22	contain	containing	880:889	arg2	cellulose					917:925	the insoluble fiber cellulose	897:925	the insoluble fiber cellulose	897:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	22	contain	containing	880:889	arg2	%					892:892	5%	891:892	5% of the insoluble fiber cellulose	891:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	3	23	theme	health	607:612	arg1	improvement					614:624	health improvement	607:624	health improvement in mice and humans	607:643	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	10	24	theme	γδ	2116:2117	arg1	cells					2121:2125	γδ T cells	2116:2125	γδ T cells	2116:2125	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	1	25	dep	BACKGROUND	101:110	arg1	essential					241:249	essential	241:249	essential	241:249	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	1	25	dep	BACKGROUND	101:110	arg1	proliferation					127:139	The continuous proliferation	112:139	The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells	112:236	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	10	26	theme	intestinal	1989:1998	arg1	cells					2005:2009	intestinal stem cells	1989:2009	intestinal stem cells	1989:2009	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	9	27	from	role	1647:1650	arg1	microenvironment					1690:1705	this microenvironment	1685:1705	this microenvironment	1685:1705	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	7	28	theme	inulin	1303:1308	arg1	diet					1310:1313	inulin diet	1303:1313	inulin diet	1303:1313	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	11	29	theme	luminal	2288:2294	arg1	environment					2296:2306	the luminal environment	2284:2306	the luminal environment in steady state	2284:2322	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	6	30	from	impact	1157:1162	arg1	compartment					1250:1260	the local immune compartment	1233:1260	the local immune compartment	1233:1260	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	30	from	impact	1157:1162	arg1	epithelium					1196:1205	the colonic epithelium	1184:1205	the colonic epithelium	1184:1205	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	30	from	impact	1157:1162	arg1	bacteria					1219:1226	intestinal bacteria	1208:1226	intestinal bacteria	1208:1226	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	1	31	theme	cells	160:164	arg1	essential					241:249	essential	241:249	essential	241:249	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	1	31	theme	cells	160:164	arg1	proliferation					127:139	The continuous proliferation	112:139	The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells	112:236	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	2	32	theme	understood	405:414	arg1	question					416:423	an important, but poorly understood question	380:423	an important, but poorly understood question	380:423	How these processes are tuned by diet and gut microbiome is an important, but poorly understood question.					
37101209	6	33	theme	cell	1031:1034	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	33	theme	cell	1031:1034	arg1	transcriptomics					1036:1050	host cell transcriptomics	1026:1050	host cell transcriptomics	1026:1050	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	9	34	theme	inulin	1715:1720	arg1	diet					1722:1725	the inulin diet	1711:1725	the inulin diet	1711:1725	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	10	35	dep	CONCLUSION	1907:1916	arg1	indicates					1929:1937	indicates	1929:1937	indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22	1929:2152	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	2	36	dep	diet	353:356	arg1	microbiome					366:375	microbiome	366:375	microbiome	366:375	How these processes are tuned by diet and gut microbiome is an important, but poorly understood question.					
37101209	0	37	theme	Inulin	0:5	arg1	diet					7:10	Inulin diet	0:10	Inulin diet	0:10	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	0	38	dep	epithelium	89:98	arg1	remodeling					70:79	remodeling	70:79	remodeling	70:79	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	8	39	theme	inulin-altered	1478:1491	arg1	microbiota					1497:1506	the inulin-altered gut microbiota	1474:1506	the inulin-altered gut microbiota	1474:1506	This effect was dependent on the inulin-altered gut microbiota, as no modulations were observed in animals deprived of microbiota, nor in mice fed cellulose-enriched diets.					
37101209	10	40	theme	IL-22	2148:2152	arg1	microbiota					2104:2113	the gut microbiota	2096:2113	the gut microbiota	2096:2113	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	10	40	theme	IL-22	2148:2152	arg1	presence					2136:2143	the presence	2132:2143	the presence of IL-22	2132:2152	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	10	40	theme	IL-22	2148:2152	arg1	cells					2121:2125	γδ T cells	2116:2125	γδ T cells	2116:2125	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	4	41	theme	colonic	738:744	arg1	bacteria					746:753	colonic bacteria	738:753	colonic bacteria	738:753	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	3	42	theme	Dietary	426:432	arg1	fibers					442:447	Dietary soluble fibers	426:447	Dietary soluble fibers	426:447	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	3	42	theme	Dietary	426:432	arg1	inulin					458:463	inulin	458:463	inulin	458:463	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	0	43	theme	diet-microbiota-immune	29:50	arg1	interactions					57:68	complex diet-microbiota-immune cell interactions	21:68	complex diet-microbiota-immune cell interactions	21:68	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	3	44	theme	soluble	434:440	arg1	fibers					442:447	Dietary soluble fibers	426:447	Dietary soluble fibers	426:447	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	3	44	theme	soluble	434:440	arg1	inulin					458:463	inulin	458:463	inulin	458:463	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	5	45	theme	inulin	979:984	arg1	inulin					979:984	inulin	979:984	inulin	979:984	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	45	theme	inulin	979:984	arg1	%					974:974	an additional 10%	958:974	an additional 10% of inulin	958:984	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	11	46	from	environment	2296:2306	arg1	state					2318:2322	steady state	2311:2322	steady state	2311:2322	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	4	47	theme	stem	783:786	arg1	functions					794:802	intestinal stem cells functions	772:802	intestinal stem cells functions	772:802	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	5	48	theme	additional	961:970	arg1	inulin					979:984	inulin	979:984	inulin	979:984	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	5	48	theme	additional	961:970	arg1	%					974:974	an additional 10%	958:974	an additional 10% of inulin	958:984	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	10	49	theme	cells	2005:2009	arg1	activity					1977:1984	the activity	1973:1984	the activity of intestinal stem cells	1973:2009	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	2	50	theme	important	383:391	arg1	question					416:423	an important, but poorly understood question	380:423	an important, but poorly understood question	380:423	How these processes are tuned by diet and gut microbiome is an important, but poorly understood question.					
37101209	6	51	theme	microbiome	1057:1066	arg1	analysis					1068:1075	16S microbiome analysis	1053:1075	16S microbiome analysis	1053:1075	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	51	theme	microbiome	1057:1066	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	9	52	theme	cell	1789:1792	arg1	population					1794:1803	this T cell population	1782:1803	this T cell population	1782:1803	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	1	53	theme	gut	278:280	arg1	barrier					293:299	the gut epithelial barrier	274:299	the gut epithelial barrier	274:299	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	7	54	theme	deeper	1412:1417	arg1	crypts					1419:1424	deeper crypts	1412:1424	deeper crypts	1412:1424	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	8	55	located	observed	1532:1539	arg1	animals					1544:1550	animals	1544:1550	animals deprived of microbiota	1544:1573	This effect was dependent on the inulin-altered gut microbiota, as no modulations were observed in animals deprived of microbiota, nor in mice fed cellulose-enriched diets.					
37101209	8	55	located	observed	1532:1539	arg2	modulations					1515:1525	no modulations	1512:1525	no modulations	1512:1525	This effect was dependent on the inulin-altered gut microbiota, as no modulations were observed in animals deprived of microbiota, nor in mice fed cellulose-enriched diets.					
37101209	10	56	theme	homeostatic	2024:2034	arg1	effect					2075:2080	an effect	2072:2080	an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22	2072:2152	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	10	56	theme	homeostatic	2024:2034	arg1	remodeling					2036:2045	a homeostatic remodeling	2022:2045	a homeostatic remodeling of the colon epithelium	2022:2069	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	3	57	theme	gut	536:538	arg1	epithelium					540:549	the gut bacterial community and gut epithelium	504:549	epithelium	540:549	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	1	58	theme	barrier	293:299	arg1	maintenance					259:269	the maintenance	255:269	the maintenance of the gut epithelial barrier and its functions	255:317	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	7	59	theme	stem	1389:1392	arg1	cells					1394:1398	intestinal stem cells	1378:1398	intestinal stem cells	1378:1398	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	11	60	theme	cross	2183:2187	arg1	kingdom					2189:2195	complex cross kingdom and cross cell type interactions	2175:2228	kingdom	2189:2195	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	6	61	theme	intestinal	1208:1217	arg1	bacteria					1219:1226	intestinal bacteria	1208:1226	intestinal bacteria	1208:1226	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	1	62	theme	regulated	192:200	arg1	differentiation					202:216	their tightly regulated differentiation	178:216	their tightly regulated differentiation to epithelial cells	178:236	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	7	63	theme	cells	1394:1398	arg1	proliferation					1361:1373	the proliferation	1357:1373	the proliferation of intestinal stem cells	1357:1398	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	4	64	theme	epithelial	824:833	arg1	structure					835:843	the epithelial structure	820:843	the epithelial structure	820:843	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	6	65	theme	mouse	1127:1131	arg1	models					1133:1138	genetically modified mouse models	1106:1138	genetically modified mouse models	1106:1138	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	65	theme	mouse	1127:1131	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	10	66	theme	colon	2054:2058	arg1	epithelium					2060:2069	the colon epithelium	2050:2069	the colon epithelium	2050:2069	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	11	67	theme	cell	2207:2210	arg1	interactions					2217:2228	complex cross kingdom and cross cell type interactions	2175:2228	interactions	2217:2228	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	9	68	theme	diet-microbiota-epithelium-immune	1855:1887	arg1	crosstalk					1896:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	7	69	theme	colon	1326:1330	arg1	epithelium					1332:1341	the colon epithelium	1322:1341	the colon epithelium	1322:1341	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	9	70	theme	γδ	1655:1656	arg1	lymphocytes					1660:1670	γδ T lymphocytes	1655:1670	γδ T lymphocytes	1655:1670	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	6	71	theme	inulin	1167:1172	arg1	intake					1174:1179	inulin intake	1167:1179	inulin intake	1167:1179	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	10	72	theme	gut	2100:2102	arg1	microbiota					2104:2113	the gut microbiota	2096:2113	the gut microbiota	2096:2113	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	6	73	theme	immune	1243:1248	arg1	compartment					1250:1260	the local immune compartment	1233:1260	the local immune compartment	1233:1260	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	1	74	theme	stem	155:158	arg1	cells					160:164	intestinal stem cells	144:164	intestinal stem cells	144:164	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	9	75	theme	lymphocytes	1660:1670	arg1	role					1647:1650	the pivotal role	1635:1650	the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment	1635:1705	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	9	76	from	importance	1837:1846	arg1	crosstalk					1896:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	the diet-microbiota-epithelium-immune system crosstalk	1851:1904	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	10	77	theme	inulin	1958:1963	arg1	intake					1948:1953	the intake	1944:1953	the intake of inulin	1944:1963	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	0	78	theme	gut	85:87	arg1	epithelium					89:98	the gut epithelium	81:98	the gut epithelium	81:98	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	9	79	theme	IL-22	1676:1680	arg1	role					1647:1650	the pivotal role	1635:1650	the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment	1635:1705	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	10	80	theme	T	2119:2119	arg1	cells					2121:2125	γδ T cells	2116:2125	γδ T cells	2116:2125	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	12	81	dep	Abstract	2331:2338	arg1	Video					2325:2329	Video	2325:2329	Video	2325:2329	Video Abstract.					
37101209	5	82	theme	same	934:937	arg1	diet					939:942	the same diet	930:942	the same diet enriched with an additional 10% of inulin	930:984	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	11	83	theme	epithelium	2270:2279	arg1	adaptation					2246:2255	the adaptation	2242:2255	the adaptation of the colon epithelium to the luminal environment in steady state	2242:2322	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	4	84	theme	bacteria	746:753	arg1	composition					723:733	the composition	719:733	the composition of colonic bacteria	719:753	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	11	85	theme	steady	2311:2316	arg1	state					2318:2322	steady state	2311:2322	steady state	2311:2322	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	3	86	from	improvement	614:624	arg1	humans					638:643	humans	638:643	humans	638:643	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	3	86	from	improvement	614:624	arg1	mice					629:632	mice	629:632	mice	629:632	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	5	87	theme	fiber	911:915	arg1	cellulose					917:925	the insoluble fiber cellulose	897:925	the insoluble fiber cellulose	897:925	METHODS Mice were fed with a diet containing 5% of the insoluble fiber cellulose or the same diet enriched with an additional 10% of inulin.					
37101209	6	88	theme	host	1026:1029	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	88	theme	host	1026:1029	arg1	transcriptomics					1036:1050	host cell transcriptomics	1026:1050	host cell transcriptomics	1026:1050	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	8	89	theme	gut	1493:1495	arg1	microbiota					1497:1506	the inulin-altered gut microbiota	1474:1506	the inulin-altered gut microbiota	1474:1506	This effect was dependent on the inulin-altered gut microbiota, as no modulations were observed in animals deprived of microbiota, nor in mice fed cellulose-enriched diets.					
37101209	0	90	theme	complex	21:27	arg1	interactions					57:68	complex diet-microbiota-immune cell interactions	21:68	complex diet-microbiota-immune cell interactions	21:68	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	1	91	theme	functions	309:317	arg1	maintenance					259:269	the maintenance	255:269	the maintenance of the gut epithelial barrier and its functions	255:317	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	1	92	theme	continuous	116:125	arg1	essential					241:249	essential	241:249	essential	241:249	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	1	92	theme	continuous	116:125	arg1	proliferation					127:139	The continuous proliferation	112:139	The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells	112:236	BACKGROUND The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	germ-free					1078:1086	germ-free	1078:1086	germ-free	1078:1086	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	combination					995:1005	a combination	993:1005	a combination of histochemistry	993:1023	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	gnotobiotic					1089:1099	gnotobiotic	1089:1099	gnotobiotic	1089:1099	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	models					1133:1138	genetically modified mouse models	1106:1138	genetically modified mouse models	1106:1138	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	analysis					1068:1075	16S microbiome analysis	1053:1075	16S microbiome analysis	1053:1075	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	6	93	theme	histochemistry	1010:1023	arg1	transcriptomics					1036:1050	host cell transcriptomics	1026:1050	host cell transcriptomics	1026:1050	Using a combination of histochemistry, host cell transcriptomics, 16S microbiome analysis, germ-free, gnotobiotic, and genetically modified mouse models, we analyzed the impact of inulin intake on the colonic epithelium, intestinal bacteria, and the local immune compartment.					
37101209	11	94	theme	cross	2201:2205	arg1	interactions					2217:2228	complex cross kingdom and cross cell type interactions	2175:2228	interactions	2217:2228	Our study indicates complex cross kingdom and cross cell type interactions involved in the adaptation of the colon epithelium to the luminal environment in steady state.					
37101209	3	95	theme	gut	508:510	arg1	community					522:530	the gut bacterial community and gut epithelium	504:549	community	522:530	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
37101209	0	96	theme	cell	52:55	arg1	interactions					57:68	complex diet-microbiota-immune cell interactions	21:68	complex diet-microbiota-immune cell interactions	21:68	Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.					
37101209	7	97	dep	RESULTS	1263:1269	arg1	show					1274:1277	show	1274:1277	show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons	1274:1442	RESULTS We show that the consumption of inulin diet alters the colon epithelium by increasing the proliferation of intestinal stem cells, leading to deeper crypts and longer colons.					
37101209	9	98	theme	T	1787:1787	arg1	population					1794:1803	this T cell population	1782:1803	this T cell population	1782:1803	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	9	99	theme	epithelium	1744:1753	arg1	remodeling					1755:1764	epithelium remodeling	1744:1764	epithelium remodeling	1744:1764	We also describe the pivotal role of γδ T lymphocytes and IL-22 in this microenvironment, as the inulin diet failed to induce epithelium remodeling in mice lacking this T cell population or cytokine, highlighting their importance in the diet-microbiota-epithelium-immune system crosstalk.					
37101209	4	100	theme	intestinal	772:781	arg1	functions					794:802	intestinal stem cells functions	772:802	intestinal stem cells functions	772:802	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	8	101	theme	cellulose-enriched	1592:1609	arg1	diets					1611:1615	cellulose-enriched diets	1592:1615	cellulose-enriched diets	1592:1615	This effect was dependent on the inulin-altered gut microbiota, as no modulations were observed in animals deprived of microbiota, nor in mice fed cellulose-enriched diets.					
37101209	10	102	theme	stem	2000:2003	arg1	cells					2005:2009	intestinal stem cells	1989:2009	intestinal stem cells	1989:2009	CONCLUSION This study indicates that the intake of inulin affects the activity of intestinal stem cells and drives a homeostatic remodeling of the colon epithelium, an effect that requires the gut microbiota, γδ T cells, and the presence of IL-22.					
37101209	4	103	theme	cells	788:792	arg1	functions					794:802	intestinal stem cells functions	772:802	intestinal stem cells functions	772:802	In this study, we tested the hypothesis that inulin consumption modifies the composition of colonic bacteria and this impacts intestinal stem cells functions, thus affecting the epithelial structure.					
37101209	3	104	theme	bacterial	512:520	arg1	community					522:530	the gut bacterial community and gut epithelium	504:549	community	522:530	Dietary soluble fibers, such as inulin, are known for their ability to impact the gut bacterial community and gut epithelium, and their consumption has been usually associated with health improvement in mice and humans.					
36842393	0	0	theme	blood	99:103	arg1	coagulation					105:115	blood coagulation	99:115	blood coagulation	99:115	A nanofiber/sponge double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing.					
36842393	8	1	theme	composite	1529:1537	arg1	membrane					1539:1546	the composite membrane	1525:1546	the composite membrane	1525:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	4	2	theme	hemostatic	841:850	arg1	efficiency					852:861	in vivo hemostatic efficiency	833:861	in vivo hemostatic efficiency	833:861	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	2	3	theme	quaternized	369:379	arg1	QCS12					391:395	QCS12	391:395	QCS12	391:395	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	3	theme	quaternized	369:379	arg1	chitosan					381:388	quaternized chitosan	369:388	quaternized chitosan (QCS12)	369:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	9	4	theme	potential	1601:1609	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	4	theme	potential	1601:1609	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	7	5	theme	collagen	1229:1236	arg1	deposition					1238:1247	collagen deposition	1229:1247	collagen deposition	1229:1247	QCP promoted collagen deposition and re-epithelization to accelerate healing and suppress scars in the full-thickness acute wound models.					
36842393	1	6	theme	severe	192:197	arg1	damage					199:204	severe damage	192:204	severe damage to the wounds	192:218	Uncontrolled bleeding and bacterial infections cause severe damage to the wounds and remain a clinical challenge.					
36842393	8	7	theme	certain	1480:1486	arg1	resistance					1488:1497	a certain resistance	1478:1497	a certain resistance to bacterial infection of the composite membrane	1478:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	8	8	theme	high	1449:1452	arg1	efficiency					1462:1471	high healing efficiency	1449:1471	high healing efficiency with a certain resistance to bacterial infection of the composite membrane	1449:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	5	9	theme	significant	941:951	arg1	invasion					968:975	significant anti-microbial invasion	941:975	significant anti-microbial invasion	941:975	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	8	10	theme	incision	1402:1409	arg1	model					1411:1415	the chronic skin incision model	1385:1415	the chronic skin incision model of diabetes mellitus	1385:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	4	11	with	stability	768:776	arg1	skin					823:826	natural skin	815:826	natural skin	815:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	6	12	theme	desirable	1164:1172	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	12	theme	desirable	1164:1172	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	12	theme	desirable	1164:1172	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	12	theme	desirable	1164:1172	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	12	theme	desirable	1164:1172	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	13	theme	other	1158:1162	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	13	theme	other	1158:1162	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	13	theme	other	1158:1162	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	13	theme	other	1158:1162	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	13	theme	other	1158:1162	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	5	14	theme	anti-microbial	953:966	arg1	invasion					968:975	significant anti-microbial invasion	941:975	significant anti-microbial invasion	941:975	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	2	15	theme	membrane	311:318	arg1	QCP					321:323	a nanofiber/sponge bilayered composite membrane (QCP)	272:324	a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12)	272:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	5	16	theme	base	905:908	arg1	bonds					868:872	The bonds	864:872	The bonds of the N-quaternary and Schiff base	864:908	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	6	17	theme	fine	1084:1087	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	17	theme	fine	1084:1087	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	17	theme	fine	1084:1087	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	17	theme	fine	1084:1087	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	17	theme	fine	1084:1087	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	2	18	theme	composite	301:309	arg1	QCP					321:323	a nanofiber/sponge bilayered composite membrane (QCP)	272:324	a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12)	272:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	19	theme	joint	401:405	arg1	approaches					407:416	joint approaches	401:416	joint approaches of electrospinning and freeze-drying	401:453	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	0	20	theme	wound	124:128	arg1	healing					130:136	wound healing	124:136	wound healing	124:136	A nanofiber/sponge double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing.					
36842393	6	21	theme	negligible	1126:1135	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	21	theme	negligible	1126:1135	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	21	theme	negligible	1126:1135	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	21	theme	negligible	1126:1135	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	21	theme	negligible	1126:1135	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	7	22	theme	wound	1340:1344	arg1	models					1346:1351	the full-thickness acute wound models	1315:1351	the full-thickness acute wound models	1315:1351	QCP promoted collagen deposition and re-epithelization to accelerate healing and suppress scars in the full-thickness acute wound models.					
36842393	2	23	theme	bilayered	291:299	arg1	QCP					321:323	a nanofiber/sponge bilayered composite membrane (QCP)	272:324	a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12)	272:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	8	24	theme	bacterial	1502:1510	arg1	infection					1512:1520	bacterial infection	1502:1520	bacterial infection of the composite membrane	1502:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	2	25	contain	containing	326:335	arg2	silicone					349:356	quaternized silicone	337:356	quaternized silicone (QP12)	337:363	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	25	contain	containing	326:335	arg2	QP12					359:362	QP12	359:362	QP12	359:362	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	25	contain	containing	326:335	arg2	chitosan					381:388	quaternized chitosan	369:388	quaternized chitosan (QCS12)	369:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	25	contain	containing	326:335	arg1	QCP					321:323	a nanofiber/sponge bilayered composite membrane (QCP)	272:324	a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12)	272:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	25	contain	containing	326:335	arg2	QCS12					391:395	QCS12	391:395	QCS12	391:395	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	4	26	dep	in	833:834	arg1	vivo					836:839	vivo	836:839	vivo	836:839	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg2	0.22 ± 0.01 g/					723:736	0.22 ± 0.01 g/(cm2·24 h)	723:746	0.22 ± 0.01 g/(cm2·24 h)	723:746	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg2	efficiency					852:861	in vivo hemostatic efficiency	833:861	in vivo hemostatic efficiency	833:861	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg2	stability					768:776	available thermal stability	750:776	available thermal stability	750:776	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg2	permeability					709:720	feasible permeability	700:720	feasible permeability (0.22 ± 0.01 g/(cm2·24 h))	700:747	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg2	properties					799:808	suitable mechanical properties	779:808	suitable mechanical properties with natural skin	779:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	27	contain	possessed	690:698	arg1	membrane					681:688	The QCP composite membrane	663:688	The QCP composite membrane	663:688	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	28	theme	in	833:834	arg1	efficiency					852:861	in vivo hemostatic efficiency	833:861	in vivo hemostatic efficiency	833:861	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	2	29	theme	quaternized	337:347	arg1	QP12					359:362	QP12	359:362	QP12	359:362	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	2	29	theme	quaternized	337:347	arg1	silicone					349:356	quaternized silicone	337:356	quaternized silicone (QP12)	337:363	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	9	30	theme	hemostatic	1629:1638	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	30	theme	hemostatic	1629:1638	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	31	theme	antibacterial	1611:1623	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	31	theme	antibacterial	1611:1623	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	7	32	from	scars	1306:1310	arg1	models					1346:1351	the full-thickness acute wound models	1315:1351	the full-thickness acute wound models	1315:1351	QCP promoted collagen deposition and re-epithelization to accelerate healing and suppress scars in the full-thickness acute wound models.					
36842393	5	33	theme	composite	916:924	arg1	membranes					926:934	composite membranes	916:934	composite membranes	916:934	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	0	34	theme	composite	34:42	arg1	membrane					44:51	double-layered composite membrane	19:51	double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing	19:136	A nanofiber/sponge double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing.					
36842393	4	35	theme	suitable	779:786	arg1	properties					799:808	suitable mechanical properties	779:808	suitable mechanical properties with natural skin	779:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	36	theme	composite	671:679	arg1	membrane					681:688	The QCP composite membrane	663:688	The QCP composite membrane	663:688	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	8	37	theme	diabetes	1420:1427	arg1	mellitus					1429:1436	diabetes mellitus	1420:1436	diabetes mellitus	1420:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	3	38	contain	containing	616:625	arg2	QP12					657:660	QP12	657:660	QP12	657:660	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	38	contain	containing	616:625	arg2	PCL					648:650	PCL	648:650	PCL	648:650	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	38	contain	containing	616:625	arg1	QCS12					577:581	QCS12	577:581	QCS12	577:581	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	38	contain	containing	616:625	arg2	poly-ε-caprolactone					627:645	poly-ε-caprolactone	627:645	poly-ε-caprolactone (PCL)	627:651	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	2	39	theme	freeze-drying	441:453	arg1	approaches					407:416	joint approaches	401:416	joint approaches of electrospinning and freeze-drying	401:453	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	4	40	theme	available	750:758	arg1	stability					768:776	available thermal stability	750:776	available thermal stability	750:776	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	6	41	theme	excellent	1190:1198	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	41	theme	excellent	1190:1198	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	41	theme	excellent	1190:1198	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	41	theme	excellent	1190:1198	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	41	theme	excellent	1190:1198	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	4	42	theme	QCP	667:669	arg1	membrane					681:688	The QCP composite membrane	663:688	The QCP composite membrane	663:688	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	9	43	theme	QCP	1569:1571	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	43	theme	QCP	1569:1571	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	2	44	theme	electrospinning	421:435	arg1	approaches					407:416	joint approaches	401:416	joint approaches of electrospinning and freeze-drying	401:453	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	0	45	theme	capable	53:59	arg1	membrane					44:51	double-layered composite membrane	19:51	double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing	19:136	A nanofiber/sponge double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing.					
36842393	6	46	theme	skin	1137:1140	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	46	theme	skin	1137:1140	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	46	theme	skin	1137:1140	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	46	theme	skin	1137:1140	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	46	theme	skin	1137:1140	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	5	47	theme	healing	1010:1016	arg1	process					1018:1024	the wound healing process	1000:1024	the wound healing process	1000:1024	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	6	48	theme	wound	1200:1204	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	48	theme	wound	1200:1204	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	48	theme	wound	1200:1204	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	48	theme	wound	1200:1204	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	48	theme	wound	1200:1204	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	2	49	theme	wound	492:496	arg1	dressing					498:505	wound dressing	492:505	wound dressing	492:505	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	4	50	theme	mechanical	788:797	arg1	properties					799:808	suitable mechanical properties	779:808	suitable mechanical properties with natural skin	779:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	1	51	theme	clinical	233:240	arg1	challenge					242:250	a clinical challenge	231:250	a clinical challenge	231:250	Uncontrolled bleeding and bacterial infections cause severe damage to the wounds and remain a clinical challenge.					
36842393	8	52	with	efficiency	1462:1471	arg1	resistance					1488:1497	a certain resistance	1478:1497	a certain resistance to bacterial infection of the composite membrane	1478:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	8	53	theme	skin	1397:1400	arg1	model					1411:1415	the chronic skin incision model	1385:1415	the chronic skin incision model of diabetes mellitus	1385:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	4	54	theme	natural	815:821	arg1	skin					823:826	natural skin	815:826	natural skin	815:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	8	55	theme	chronic	1389:1395	arg1	model					1411:1415	the chronic skin incision model	1385:1415	the chronic skin incision model of diabetes mellitus	1385:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	5	56	theme	N-quaternary	881:892	arg1	base					905:908	the N-quaternary and Schiff base	877:908	base	905:908	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	3	57	contain	containing	547:556	arg2	COL					568:570	COL	568:570	COL	568:570	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	57	contain	containing	547:556	arg1	QCC					542:544	QCC	542:544	QCC	542:544	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	57	contain	containing	547:556	arg2	collagen					558:565	collagen	558:565	collagen (COL)	558:571	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	57	contain	containing	547:556	arg2	QCS12					577:581	QCS12	577:581	QCS12	577:581	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	57	contain	containing	547:556	arg1	sponge					534:539	a sponge	532:539	a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12	532:660	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	8	58	theme	membrane	1539:1546	arg1	infection					1512:1520	bacterial infection	1502:1520	bacterial infection of the composite membrane	1502:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	5	59	theme	eligible	1034:1041	arg1	microenvironment					1043:1058	an eligible microenvironment	1031:1058	an eligible microenvironment	1031:1058	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	8	60	theme	mellitus	1429:1436	arg1	model					1411:1415	the chronic skin incision model	1385:1415	the chronic skin incision model of diabetes mellitus	1385:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	1	61	theme	Uncontrolled	139:150	arg1	infections					175:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections cause severe damage to the wounds and remain a clinical challenge.					
36842393	5	62	theme	wound	1004:1008	arg1	healing					1010:1016	the wound healing	1000:1016	the wound healing process	1000:1024	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	8	63	theme	healing	1454:1460	arg1	efficiency					1462:1471	high healing efficiency	1449:1471	high healing efficiency with a certain resistance to bacterial infection of the composite membrane	1449:1546	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	2	64	theme	nanofiber/sponge	274:289	arg1	QCP					321:323	a nanofiber/sponge bilayered composite membrane (QCP)	272:324	a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12)	272:396	Here, we developed a nanofiber/sponge bilayered composite membrane (QCP) containing quaternized silicone (QP12) and quaternized chitosan (QCS12) by joint approaches of electrospinning and freeze-drying and investigated their potential for wound dressing.					
36842393	9	65	theme	wound	1640:1644	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	65	theme	wound	1640:1644	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	1	66	theme	bleeding	152:159	arg1	infections					175:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections cause severe damage to the wounds and remain a clinical challenge.					
36842393	4	67	with	efficiency	852:861	arg1	skin					823:826	natural skin	815:826	natural skin	815:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	9	68	theme	composite	1573:1581	arg1	dressing					1646:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	a potential antibacterial and hemostatic wound dressing	1599:1653	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	9	68	theme	composite	1573:1581	arg1	membrane					1583:1590	the QCP composite membrane	1565:1590	the QCP composite membrane	1565:1590	Taken together, the QCP composite membrane may be a potential antibacterial and hemostatic wound dressing.					
36842393	4	69	theme	thermal	760:766	arg1	stability					768:776	available thermal stability	750:776	available thermal stability	750:776	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	70	theme	feasible	700:707	arg1	0.22 ± 0.01 g/					723:736	0.22 ± 0.01 g/(cm2·24 h)	723:746	0.22 ± 0.01 g/(cm2·24 h)	723:746	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	70	theme	feasible	700:707	arg1	permeability					709:720	feasible permeability	700:720	feasible permeability (0.22 ± 0.01 g/(cm2·24 h))	700:747	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	8	71	from	evaluation	1371:1380	arg1	model					1411:1415	the chronic skin incision model	1385:1415	the chronic skin incision model of diabetes mellitus	1385:1436	Furthermore, the evaluation in the chronic skin incision model of diabetes mellitus manifested high healing efficiency with a certain resistance to bacterial infection of the composite membrane.					
36842393	5	72	theme	Schiff	898:903	arg1	base					905:908	the N-quaternary and Schiff base	877:908	base	905:908	The bonds of the N-quaternary and Schiff base endow composite membranes with significant anti-microbial invasion, potentially enhancing the wound healing process with an eligible microenvironment.					
36842393	7	73	theme	full-thickness	1319:1332	arg1	models					1346:1351	the full-thickness acute wound models	1315:1351	the full-thickness acute wound models	1315:1351	QCP promoted collagen deposition and re-epithelization to accelerate healing and suppress scars in the full-thickness acute wound models.					
36842393	3	74	theme	nanofibrous	589:599	arg1	membrane					601:608	a nanofibrous membrane	587:608	a nanofibrous membrane (MQP)	587:614	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	3	74	theme	nanofibrous	589:599	arg1	MQP					611:613	MQP	611:613	MQP	611:613	The QCP was composed of a sponge (QCC) containing collagen (COL) and QCS12 and a nanofibrous membrane (MQP) containing poly-ε-caprolactone (PCL) and QP12.					
36842393	7	75	theme	acute	1334:1338	arg1	models					1346:1351	the full-thickness acute wound models	1315:1351	the full-thickness acute wound models	1315:1351	QCP promoted collagen deposition and re-epithelization to accelerate healing and suppress scars in the full-thickness acute wound models.					
36842393	1	76	theme	bacterial	165:173	arg1	infections					175:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections	139:184	Uncontrolled bleeding and bacterial infections cause severe damage to the wounds and remain a clinical challenge.					
36842393	4	77	with	properties	799:808	arg1	skin					823:826	natural skin	815:826	natural skin	815:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	4	78	with	permeability	709:720	arg1	skin					823:826	natural skin	815:826	natural skin	815:826	The QCP composite membrane possessed feasible permeability (0.22 ± 0.01 g/(cm2·24 h)), available thermal stability, suitable mechanical properties with natural skin, and in vivo hemostatic efficiency.					
36842393	0	79	theme	double-layered	19:32	arg1	membrane					44:51	double-layered composite membrane	19:51	double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing	19:136	A nanofiber/sponge double-layered composite membrane capable of inhibiting infection and promoting blood coagulation during wound healing.					
36842393	6	80	theme	low	1108:1110	arg1	hemocompatibility					1089:1105	fine hemocompatibility	1084:1105	fine hemocompatibility	1084:1105	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	80	theme	low	1108:1110	arg1	cytotoxicity					1112:1123	low cytotoxicity	1108:1123	low cytotoxicity	1108:1123	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	80	theme	low	1108:1110	arg1	dressing					1206:1213	an excellent wound dressing	1187:1213	an excellent wound dressing	1187:1213	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	80	theme	low	1108:1110	arg1	biosafety					1174:1182	other desirable biosafety	1158:1182	other desirable biosafety	1158:1182	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36842393	6	80	theme	low	1108:1110	arg1	irritation					1142:1151	negligible skin irritation	1126:1151	negligible skin irritation	1126:1151	Meanwhile, QCP evinced fine hemocompatibility, low cytotoxicity, negligible skin irritation, and other desirable biosafety as an excellent wound dressing.					
36524824	0	0	theme	Mycobacteria	85:96	arg1	Synthesis					32:40	Synthesis	32:40	Synthesis via the Staudinger Reaction	32:68	Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.					
36524824	0	0	theme	Mycobacteria	85:96	arg1	Capture					74:80	Capture	74:80	Capture of Mycobacteria	74:96	Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.					
36524824	3	1	theme	1:1	640:642	arg1	ratio					664:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	1	2	theme	HEMA	158:161	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	4	3	theme	perfluorophenyl	912:926	arg1	nitrene					928:934	the photogenerated singlet perfluorophenyl nitrene	885:934	the photogenerated singlet perfluorophenyl nitrene	885:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	8	4	theme	naked	1492:1496	arg1	eye					1498:1500	the naked eye	1488:1500	the naked eye	1488:1500	In addition, the captured bacteria could be visualized by the naked eye under the illumination of a hand-held UV lamp.					
36524824	3	5	theme	trehalose	506:514	arg1	density					495:501	The grafting density	482:501	The grafting density of trehalose	482:514	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	5	6	theme	Mycobacterium	1089:1101	arg1	smegmatis					1103:1111	Mycobacterium smegmatis	1089:1111	Mycobacterium smegmatis	1089:1111	To demonstrate the ability of the trehalose glycopolymer to capture mycobacteria, arrays of the trehalose glycopolymer were fabricated and treated with Mycobacterium smegmatis.					
36524824	2	7	theme	room	371:374	arg1	temperature					376:386	room temperature	371:386	room temperature	371:386	The reaction occurred rapidly at room temperature without the use of any catalyst, giving the trehalose glycopolymers over 68% yield after 1 h.					
36524824	7	8	theme	glycopolymer	1416:1427	arg1	concentration					1385:1397	the concentration	1381:1397	the concentration of the trehalose glycopolymer	1381:1427	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	4	9	theme	insertion	863:871	arg1	reaction					873:880	the C-H insertion reaction	855:880	the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene	855:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	5	10	theme	trehalose	1033:1041	arg1	glycopolymer					1043:1054	the trehalose glycopolymer	1029:1054	the trehalose glycopolymer	1029:1054	To demonstrate the ability of the trehalose glycopolymer to capture mycobacteria, arrays of the trehalose glycopolymer were fabricated and treated with Mycobacterium smegmatis.					
36524824	3	11	theme	copolymer	541:549	arg1	composition					551:561	the copolymer composition	537:561	the copolymer composition in poly(HEMA-co-HEMA-PFPA)	537:588	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	8	12	theme	hand-held	1530:1538	arg1	lamp					1543:1546	a hand-held UV lamp	1528:1546	a hand-held UV lamp	1528:1546	In addition, the captured bacteria could be visualized by the naked eye under the illumination of a hand-held UV lamp.					
36524824	3	13	theme	grafting	486:493	arg1	density					495:501	The grafting density	482:501	The grafting density of trehalose	482:514	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	6	14	theme	optical	1131:1137	arg1	fluorescence					1140:1151	the optical, fluorescence, and scanning electron microscopy	1127:1185	fluorescence	1140:1151	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	7	15	from	trehalose	1327:1335	arg1	glycopolymer					1354:1365	the trehalose glycopolymer	1340:1365	the trehalose glycopolymer	1340:1365	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	2	16	theme	catalyst	411:418	arg1	use					400:402	the use	396:402	the use of any catalyst	396:418	The reaction occurred rapidly at room temperature without the use of any catalyst, giving the trehalose glycopolymers over 68% yield after 1 h.					
36524824	3	17	theme	HEMA/HEMA-PFPA	644:657	arg1	ratio					664:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	4	18	theme	thin	778:781	arg1	layer					831:835	the adhesion layer	818:835	the adhesion layer	818:835	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	18	theme	thin	778:781	arg1	film					783:786	a thin film	776:786	a thin film of poly(HEMA-co-HEMA-PFPA)	776:813	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	0	19	theme	Trehalose-Grafted	0:16	arg1	Glycopolymer					18:29	Trehalose-Grafted Glycopolymer	0:29	Trehalose-Grafted Glycopolymer	0:29	Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.					
36524824	6	20	from	fluorescence	1140:1151	arg1	Results					1114:1120	Results	1114:1120	Results from the optical, fluorescence, and scanning electron microscopy	1114:1185	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	2	21	theme	%	463:463	arg1	yield					465:469	68% yield	461:469	68% yield after 1 h	461:479	The reaction occurred rapidly at room temperature without the use of any catalyst, giving the trehalose glycopolymers over 68% yield after 1 h.					
36524824	3	22	theme	feed	659:662	arg1	ratio					664:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	1:1 HEMA/HEMA-PFPA feed ratio	640:668	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	4	23	theme	poly	791:794	arg1	layer					831:835	the adhesion layer	818:835	the adhesion layer	818:835	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	23	theme	poly	791:794	arg1	film					783:786	a thin film	776:786	a thin film of poly(HEMA-co-HEMA-PFPA)	776:813	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	5	24	theme	glycopolymer	1043:1054	arg1	arrays					1019:1024	arrays	1019:1024	arrays of the trehalose glycopolymer	1019:1054	To demonstrate the ability of the trehalose glycopolymer to capture mycobacteria, arrays of the trehalose glycopolymer were fabricated and treated with Mycobacterium smegmatis.					
36524824	2	25	theme	68	461:462	arg1	%					463:463	%	463:463	%	463:463	The reaction occurred rapidly at room temperature without the use of any catalyst, giving the trehalose glycopolymers over 68% yield after 1 h.					
36524824	3	26	from	ratio	664:668	arg1	TP2					623:625	TP2	623:625	TP2	623:625	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	26	from	ratio	664:668	arg1	TP1					610:612	TP1	610:612	TP1	610:612	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	26	from	ratio	664:668	arg1	%					607:607	6.1%	604:607	6.1% (TP1)	604:613	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	26	from	ratio	664:668	arg1	%					620:620	37%	618:620	37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio	618:668	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	1	27	theme	new	101:103	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	2	28	theme	trehalose	432:440	arg1	glycopolymers					442:454	the trehalose glycopolymers	428:454	the trehalose glycopolymers	428:454	The reaction occurred rapidly at room temperature without the use of any catalyst, giving the trehalose glycopolymers over 68% yield after 1 h.					
36524824	8	29	theme	UV	1540:1541	arg1	lamp					1543:1546	a hand-held UV lamp	1528:1546	a hand-held UV lamp	1528:1546	In addition, the captured bacteria could be visualized by the naked eye under the illumination of a hand-held UV lamp.					
36524824	1	30	theme	trehalose-grafted	105:121	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	7	31	theme	mycobacteria	1278:1289	arg1	mycobacteria					1278:1289	mycobacteria	1278:1289	mycobacteria	1278:1289	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	7	31	theme	mycobacteria	1278:1289	arg1	amount					1268:1273	The amount	1264:1273	The amount of mycobacteria	1264:1289	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	4	32	attach	attached	727:734	arg3	slides					745:750	glass slides	739:750	glass slides	739:750	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	32	attach	attached	727:734	arg2	glycopolymer					699:710	The trehalose glycopolymer	685:710	The trehalose glycopolymer	685:710	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	32	attach	attached	727:734	arg3	wafers					763:768	silicon wafers	755:768	silicon wafers	755:768	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	33	theme	C-H	859:861	arg1	reaction					873:880	the C-H insertion reaction	855:880	the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene	855:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	7	34	dep	captured	1291:1298	arg1	increased					1300:1308	increased	1300:1308	captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer	1291:1427	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	3	35	from	10:1	631:634	arg1	TP2					623:625	TP2	623:625	TP2	623:625	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	35	from	10:1	631:634	arg1	TP1					610:612	TP1	610:612	TP1	610:612	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	35	from	10:1	631:634	arg1	%					607:607	6.1%	604:607	6.1% (TP1)	604:613	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	35	from	10:1	631:634	arg1	%					620:620	37%	618:620	37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio	618:668	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	1	36	theme	diphenylphosphine-derivatized	297:325	arg1	trehalose					327:335	a diphenylphosphine-derivatized trehalose	295:335	a diphenylphosphine-derivatized trehalose	295:335	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	4	37	theme	silicon	755:761	arg1	wafers					763:768	silicon wafers	755:768	silicon wafers	755:768	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	8	38	theme	lamp	1543:1546	arg1	illumination					1512:1523	the illumination	1508:1523	the illumination of a hand-held UV lamp	1508:1546	In addition, the captured bacteria could be visualized by the naked eye under the illumination of a hand-held UV lamp.					
36524824	4	39	theme	adhesion	822:829	arg1	layer					831:835	the adhesion layer	818:835	the adhesion layer	818:835	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	39	theme	adhesion	822:829	arg1	film					783:786	a thin film	776:786	a thin film of poly(HEMA-co-HEMA-PFPA)	776:813	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	7	40	theme	trehalose	1344:1352	arg1	glycopolymer					1354:1365	the trehalose glycopolymer	1340:1365	the trehalose glycopolymer	1340:1365	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	1	41	theme	poly	123:126	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	0	42	theme	Staudinger	50:59	arg1	Reaction					61:68	the Staudinger Reaction	46:68	the Staudinger Reaction	46:68	Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.					
36524824	5	43	theme	glycopolymer	981:992	arg1	ability					956:962	the ability	952:962	the ability of the trehalose glycopolymer to capture mycobacteria	952:1016	To demonstrate the ability of the trehalose glycopolymer to capture mycobacteria, arrays of the trehalose glycopolymer were fabricated and treated with Mycobacterium smegmatis.					
36524824	5	44	theme	trehalose	971:979	arg1	glycopolymer					981:992	the trehalose glycopolymer	967:992	the trehalose glycopolymer	967:992	To demonstrate the ability of the trehalose glycopolymer to capture mycobacteria, arrays of the trehalose glycopolymer were fabricated and treated with Mycobacterium smegmatis.					
36524824	6	45	theme	trehalose	1240:1248	arg1	glycopolymer					1250:1261	the trehalose glycopolymer	1236:1261	the trehalose glycopolymer	1236:1261	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	3	46	from	composition	551:561	arg1	HEMA-co-HEMA-PFPA					571:587	HEMA-co-HEMA-PFPA	571:587	HEMA-co-HEMA-PFPA	571:587	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	3	46	from	composition	551:561	arg1	poly					566:569	poly	566:569	poly(HEMA-co-HEMA-PFPA)	566:588	The grafting density of trehalose can be controlled by the copolymer composition in poly(HEMA-co-HEMA-PFPA), resulting in 6.1% (TP1) or 37% (TP2) at 10:1 and 1:1 HEMA/HEMA-PFPA feed ratio, respectively.					
36524824	8	47	theme	captured	1447:1454	arg1	bacteria					1456:1463	the captured bacteria	1443:1463	the captured bacteria	1443:1463	In addition, the captured bacteria could be visualized by the naked eye under the illumination of a hand-held UV lamp.					
36524824	4	48	theme	glass	739:743	arg1	slides					745:750	glass slides	739:750	glass slides	739:750	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	0	49	dep	Synthesis	32:40	arg1	Glycopolymer					18:29	Trehalose-Grafted Glycopolymer	0:29	Trehalose-Grafted Glycopolymer	0:29	Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.					
36524824	1	50	theme	2-hydroxyethyl	128:141	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	4	51	theme	trehalose	689:697	arg1	glycopolymer					699:710	The trehalose glycopolymer	685:710	The trehalose glycopolymer	685:710	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	7	52	theme	trehalose	1406:1414	arg1	glycopolymer					1416:1427	the trehalose glycopolymer	1402:1427	the trehalose glycopolymer	1402:1427	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	6	53	theme	scanning	1158:1165	arg1	microscopy					1176:1185	the optical, fluorescence, and scanning electron microscopy	1127:1185	microscopy	1176:1185	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	1	54	theme	methacrylate	143:154	arg1	glycopolymer					164:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer	99:175	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	4	55	theme	singlet	904:910	arg1	nitrene					928:934	the photogenerated singlet perfluorophenyl nitrene	885:934	the photogenerated singlet perfluorophenyl nitrene	885:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	7	56	theme	percent	1319:1325	arg1	trehalose					1327:1335	the percent trehalose	1315:1335	the percent trehalose in the trehalose glycopolymer	1315:1365	The amount of mycobacteria captured increased with the percent trehalose in the trehalose glycopolymer and also with the concentration of the trehalose glycopolymer.					
36524824	6	57	from	microscopy	1176:1185	arg1	Results					1114:1120	Results	1114:1120	Results from the optical, fluorescence, and scanning electron microscopy	1114:1185	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	1	58	theme	-mediated	229:237	arg1	reaction					250:257	the perfluorophenyl azide (PFPA)-mediated Staudinger reaction	197:257	the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose	197:335	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
36524824	4	59	theme	photogenerated	889:902	arg1	nitrene					928:934	the photogenerated singlet perfluorophenyl nitrene	885:934	the photogenerated singlet perfluorophenyl nitrene	885:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	4	60	theme	nitrene	928:934	arg1	reaction					873:880	the C-H insertion reaction	855:880	the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene	855:934	The trehalose glycopolymer was covalently attached on glass slides or silicon wafers using a thin film of poly(HEMA-co-HEMA-PFPA) as the adhesion layer, achieved through the C-H insertion reaction of the photogenerated singlet perfluorophenyl nitrene.					
36524824	6	61	theme	electron	1167:1174	arg1	microscopy					1176:1185	the optical, fluorescence, and scanning electron microscopy	1127:1185	microscopy	1176:1185	Results from the optical, fluorescence, and scanning electron microscopy showed that mycobacteria were indeed captured on the trehalose glycopolymer.					
36524824	1	62	theme	Staudinger	239:248	arg1	reaction					250:257	the perfluorophenyl azide (PFPA)-mediated Staudinger reaction	197:257	the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose	197:335	A new trehalose-grafted poly(2-hydroxyethyl methacrylate) (HEMA) glycopolymer was synthesized via the perfluorophenyl azide (PFPA)-mediated Staudinger reaction between poly(HEMA-co-HEMA-PFPA) and a diphenylphosphine-derivatized trehalose.					
35131519	11	0	theme	PE	1448:1449	arg1	definition					1434:1443	the widely accepted definition	1414:1443	the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line	1414:1500	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	1	theme	stroma	1577:1582	arg1	extension					1552:1560	a direct extension	1543:1560	a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line	1543:1704	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	1	theme	stroma	1577:1582	arg1	it					1537:1538	it	1537:1538	it	1537:1538	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	2	theme	corneal	1569:1575	arg1	stroma					1577:1582	the corneal stroma	1565:1582	the corneal stroma	1565:1582	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	4	3	theme	trabeculectomy	511:524	arg1	specimens					526:534	2 trabeculectomy specimens	509:534	2 trabeculectomy specimens	509:534	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	5	4	theme	PE	678:679	arg1	composition					663:673	the extracellular matrix composition	638:673	the extracellular matrix composition of PE	638:679	Immunohistochemistry was performed on 5 specimens to characterize the extracellular matrix composition of PE.					
35131519	11	5	dep	CONCLUSIONS	1387:1397	arg1	contrast					1402:1409	contrast	1402:1409	contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line	1402:1500	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	2	6	theme	Case	344:347	arg1	series					349:354	DESIGN Case series	337:354	DESIGN Case series.	337:355	DESIGN Case series.					
35131519	4	7	dep	specimens	477:485	arg1	n =					488:490	n = 9	488:492	n = 9; 7 autopsy and 2 trabeculectomy specimens	488:534	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	7	8	theme	trabecular	939:948	arg1	n =					960:962	n = 1	960:964	n = 1	960:964	These nubs were located anterior to Schwalbe's line (n = 4), posteriorly (n = 1), partially embedded in the trabecular meshwork (n = 1), or at Schwalbe's line (n = 2).					
35131519	7	8	theme	trabecular	939:948	arg1	meshwork					950:957	the trabecular meshwork	935:957	the trabecular meshwork (n = 1)	935:965	These nubs were located anterior to Schwalbe's line (n = 4), posteriorly (n = 1), partially embedded in the trabecular meshwork (n = 1), or at Schwalbe's line (n = 2).					
35131519	11	9	with	extension	1552:1560	arg1	locations					1598:1606	variable locations	1589:1606	variable locations	1589:1606	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	9	10	theme	keratan	1210:1216	arg1	sulfate					1218:1224	keratan sulfate	1210:1224	keratan sulfate	1210:1224	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	9	11	from	PE	1266:1267	arg1	similar					1239:1245	similar	1239:1245	similar	1239:1245	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	4	12	theme	METHODS	412:418	arg1	Sections					420:427	METHODS Sections	412:427	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens)	412:535	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	6	13	theme	collagen	740:747	arg1	nubs					724:727	nubs	724:727	nubs	724:727	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	1	14	theme	peripheral	249:258	arg1	variable					280:287	a peripheral corneal stromal nub variable	247:287	a peripheral corneal stromal nub variable in location with abnormal extracellular matrix	247:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	8	15	theme	corneal	1082:1088	arg1	stroma					1090:1095	the corneal stroma	1078:1095	the corneal stroma	1078:1095	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	1	16	theme	posterior	123:131	arg1	PE					146:147	PE	146:147	PE	146:147	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	16	theme	posterior	123:131	arg1	embryotoxon					133:143	posterior embryotoxon	123:143	posterior embryotoxon (PE)	123:148	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	6	17	theme	Descemet	812:819	arg1	membrane					821:828	Descemet membrane	812:828	Descemet membrane	812:828	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	9	18	from	similar	1239:1245	arg1	PE					1266:1267	PE	1266:1267	PE	1266:1267	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	6	19	theme	whorled	732:738	arg1	collagen					740:747	whorled collagen	732:747	whorled collagen extending from the corneal stroma	732:781	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	7	20	from	meshwork	950:957	arg1	embedded					923:930	embedded	923:930	embedded	923:930	These nubs were located anterior to Schwalbe's line (n = 4), posteriorly (n = 1), partially embedded in the trabecular meshwork (n = 1), or at Schwalbe's line (n = 2).					
35131519	10	21	theme	immunohistochemical	1357:1375	arg1	features					1377:1384	its immunohistochemical features	1353:1384	its immunohistochemical features	1353:1384	MAIN OUTCOME MEASURES Identify location of PE and its immunohistochemical features.					
35131519	1	22	from	variable	280:287	arg1	location					292:299	location	292:299	location	292:299	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	3	23	from	patients	394:401	arg1	specimens					379:387	specimens	379:387	specimens from patients with PE	379:409	PARTICIPANTS Archived specimens from patients with PE.					
35131519	5	24	theme	matrix	656:661	arg1	composition					663:673	the extracellular matrix composition	638:673	the extracellular matrix composition of PE	638:679	Immunohistochemistry was performed on 5 specimens to characterize the extracellular matrix composition of PE.					
35131519	1	25	with	variable	280:287	arg1	matrix					329:334	abnormal extracellular matrix	306:334	abnormal extracellular matrix	306:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	9	26	theme	sulfate	1218:1224	arg1	staining					1226:1233	Lumican and keratan sulfate staining	1198:1233	Lumican and keratan sulfate staining	1198:1233	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	0	27	theme	Posterior	0:8	arg1	Embryotoxon					10:20	Posterior Embryotoxon	0:20	Posterior Embryotoxon Revisited	0:30	Posterior Embryotoxon Revisited: An Immunohistologic Study.					
35131519	4	28	theme	light	554:558	arg1	microscopy					560:569	light microscopy	554:569	light microscopy	554:569	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	12	29	theme	corneal	1813:1819	arg1	stroma					1821:1826	corneal stroma	1813:1826	corneal stroma	1813:1826	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	10	30	theme	OUTCOME	1308:1314	arg1	MEASURES					1316:1323	MAIN OUTCOME MEASURES	1303:1323	MAIN OUTCOME MEASURES	1303:1323	MAIN OUTCOME MEASURES Identify location of PE and its immunohistochemical features.					
35131519	1	31	theme	immunopathologic	94:109	arg1	features					111:118	the immunopathologic features	90:118	the immunopathologic features of posterior embryotoxon (PE)	90:148	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	10	32	theme	PE	1346:1347	arg1	location					1334:1341	location	1334:1341	location of PE	1334:1347	MAIN OUTCOME MEASURES Identify location of PE and its immunohistochemical features.					
35131519	10	32	theme	PE	1346:1347	arg1	features					1377:1384	its immunohistochemical features	1353:1384	its immunohistochemical features	1353:1384	MAIN OUTCOME MEASURES Identify location of PE and its immunohistochemical features.					
35131519	8	33	theme	collagen	1106:1113	arg1	staining					1119:1126	collagen III staining	1106:1126	collagen III staining	1106:1126	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	1	34	theme	stromal	268:274	arg1	variable					280:287	a peripheral corneal stromal nub variable	247:287	a peripheral corneal stromal nub variable in location with abnormal extracellular matrix	247:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	8	35	dep	focal	1132:1136	arg1	intense					1156:1162	intense	1156:1162	intense	1156:1162	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	10	36	theme	MAIN	1303:1306	arg1	MEASURES					1316:1323	MAIN OUTCOME MEASURES	1303:1323	MAIN OUTCOME MEASURES	1303:1323	MAIN OUTCOME MEASURES Identify location of PE and its immunohistochemical features.					
35131519	1	37	theme	anterior	185:192	arg1	line					215:218	an anterior displaced Schwalbe's line	182:218	an anterior displaced Schwalbe's line	182:218	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	37	theme	anterior	185:192	arg1	it					172:173	it	172:173	it	172:173	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	38	theme	nub	276:278	arg1	variable					280:287	a peripheral corneal stromal nub variable	247:287	a peripheral corneal stromal nub variable in location with abnormal extracellular matrix	247:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	4	39	from	specimens	477:485	arg1	Sections					420:427	METHODS Sections	412:427	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens)	412:535	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	12	40	theme	matrix	1791:1796	arg1	similar					1802:1808	similar	1802:1808	similar	1802:1808	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	12	40	theme	matrix	1791:1796	arg1	composition					1757:1767	the composition	1753:1767	the composition of PE's extracellular matrix	1753:1796	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	3	41	with	patients	394:401	arg1	PE					408:409	PE	408:409	PE	408:409	PARTICIPANTS Archived specimens from patients with PE.					
35131519	1	42	theme	displaced	194:202	arg1	line					215:218	an anterior displaced Schwalbe's line	182:218	an anterior displaced Schwalbe's line	182:218	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	42	theme	displaced	194:202	arg1	it					172:173	it	172:173	it	172:173	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	0	43	theme	Immunohistologic	36:51	arg1	Study					53:57	An Immunohistologic Study	33:57	An Immunohistologic Study	33:57	Posterior Embryotoxon Revisited: An Immunohistologic Study.					
35131519	4	44	dep	n =	488:490	arg1	specimens					526:534	2 trabeculectomy specimens	509:534	2 trabeculectomy specimens	509:534	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	4	44	dep	n =	488:490	arg1	autopsy					497:503	7 autopsy	495:503	7 autopsy	495:503	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	8	45	theme	I	1023:1023	arg1	labeling					1025:1032	collagen I labeling	1014:1032	collagen I labeling of the PE stroma	1014:1049	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	6	46	theme	Posterior	690:698	arg1	embryotoxon					700:710	Posterior embryotoxon	690:710	Posterior embryotoxon	690:710	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	8	47	theme	corneal	1182:1188	arg1	stroma					1190:1195	the corneal stroma	1178:1195	the corneal stroma	1178:1195	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	8	48	theme	collagen	1014:1021	arg1	labeling					1025:1032	collagen I labeling	1014:1032	collagen I labeling of the PE stroma	1014:1049	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	0	49	dep	Study	53:57	arg1	Embryotoxon					10:20	Posterior Embryotoxon	0:20	Posterior Embryotoxon Revisited	0:30	Posterior Embryotoxon Revisited: An Immunohistologic Study.					
35131519	12	50	theme	staining	1857:1864	arg1	intensity					1866:1874	staining intensity	1857:1874	staining intensity	1857:1874	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	12	51	theme	Immunohistochemical	1707:1725	arg1	examination					1727:1737	Immunohistochemical examination	1707:1737	Immunohistochemical examination	1707:1737	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	11	52	theme	variable	1589:1596	arg1	locations					1598:1606	variable locations	1589:1606	variable locations	1589:1606	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	53	theme	histologic	1503:1512	arg1	evidence					1514:1521	histologic evidence	1503:1521	histologic evidence	1503:1521	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	2	54	theme	DESIGN	337:342	arg1	series					349:354	DESIGN Case series	337:354	DESIGN Case series.	337:355	DESIGN Case series.					
35131519	9	55	theme	Lumican	1198:1204	arg1	staining					1226:1233	Lumican and keratan sulfate staining	1198:1233	Lumican and keratan sulfate staining	1198:1233	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	11	56	theme	direct	1545:1550	arg1	extension					1552:1560	a direct extension	1543:1560	a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line	1543:1704	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	56	theme	direct	1545:1550	arg1	it					1537:1538	it	1537:1538	it	1537:1538	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	5	57	theme	extracellular	642:654	arg1	composition					663:673	the extracellular matrix composition	638:673	the extracellular matrix composition of PE	638:679	Immunohistochemistry was performed on 5 specimens to characterize the extracellular matrix composition of PE.					
35131519	11	58	theme	Schwalbe	1488:1495	arg1	line					1497:1500	a prominent, anteriorly displaced Schwalbe line	1454:1500	a prominent, anteriorly displaced Schwalbe line	1454:1500	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	1	59	theme	embryotoxon	133:143	arg1	features					111:118	the immunopathologic features	90:118	the immunopathologic features of posterior embryotoxon (PE)	90:148	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	60	theme	abnormal	306:313	arg1	matrix					329:334	abnormal extracellular matrix	306:334	abnormal extracellular matrix	306:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	8	61	theme	PE	1041:1042	arg1	stroma					1044:1049	the PE stroma	1037:1049	the PE stroma	1037:1049	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	11	62	theme	attenuated	1630:1639	arg1	membrane					1650:1657	the attenuated Descemet membrane	1626:1657	the attenuated Descemet membrane	1626:1657	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	11	63	theme	prominent	1456:1464	arg1	line					1497:1500	a prominent, anteriorly displaced Schwalbe line	1454:1500	a prominent, anteriorly displaced Schwalbe line	1454:1500	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	1	64	theme	corneal	260:266	arg1	variable					280:287	a peripheral corneal stromal nub variable	247:287	a peripheral corneal stromal nub variable in location with abnormal extracellular matrix	247:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	65	dep	PURPOSE	60:66	arg1	describes					80:88	describes	80:88	describes the immunopathologic features of posterior embryotoxon (PE)	80:148	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	1	65	dep	PURPOSE	60:66	arg1	demonstrates					154:165	demonstrates	154:165	demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix	154:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	4	66	dep	formalin-fixed	443:456	arg1	paraffin-embedded					459:475	paraffin-embedded	459:475	paraffin-embedded	459:475	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	4	67	theme	formalin-fixed	443:456	arg1	specimens					477:485	archived formalin-fixed, paraffin-embedded specimens	434:485	archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens)	434:535	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	6	68	theme	corneal	768:774	arg1	stroma					776:781	the corneal stroma	764:781	the corneal stroma	764:781	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	12	69	theme	extracellular	1777:1789	arg1	matrix					1791:1796	PE's extracellular matrix	1772:1796	PE's extracellular matrix	1772:1796	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	9	70	theme	corneal	1287:1293	arg1	stroma					1295:1300	the corneal stroma	1283:1300	the corneal stroma	1283:1300	Lumican and keratan sulfate staining was similar or less intense in PE compared with the corneal stroma.					
35131519	4	71	theme	archived	434:441	arg1	specimens					477:485	archived formalin-fixed, paraffin-embedded specimens	434:485	archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens)	434:535	METHODS Sections from archived formalin-fixed, paraffin-embedded specimens (n = 9; 7 autopsy and 2 trabeculectomy specimens) were examined by light microscopy.					
35131519	11	72	dep	prominent	1456:1464	arg1	displaced					1478:1486	displaced	1478:1486	displaced	1478:1486	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	7	73	from	embedded	923:930	arg1	n =					960:962	n = 1	960:964	n = 1	960:964	These nubs were located anterior to Schwalbe's line (n = 4), posteriorly (n = 1), partially embedded in the trabecular meshwork (n = 1), or at Schwalbe's line (n = 2).					
35131519	7	73	from	embedded	923:930	arg1	meshwork					950:957	the trabecular meshwork	935:957	the trabecular meshwork (n = 1)	935:965	These nubs were located anterior to Schwalbe's line (n = 4), posteriorly (n = 1), partially embedded in the trabecular meshwork (n = 1), or at Schwalbe's line (n = 2).					
35131519	11	74	theme	Descemet	1641:1648	arg1	membrane					1650:1657	the attenuated Descemet membrane	1626:1657	the attenuated Descemet membrane	1626:1657	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
35131519	8	75	theme	stroma	1044:1049	arg1	labeling					1025:1032	collagen I labeling	1014:1032	collagen I labeling of the PE stroma	1014:1049	Qualitatively, collagen I labeling of the PE stroma was similar or weaker than the corneal stroma, whereas collagen III staining was focal and slightly more intense compared with the corneal stroma.					
35131519	1	76	theme	extracellular	315:327	arg1	matrix					329:334	abnormal extracellular matrix	306:334	abnormal extracellular matrix	306:334	PURPOSE This series describes the immunopathologic features of posterior embryotoxon (PE) and demonstrates that it is not an anterior displaced Schwalbe's line as commonly described, but a peripheral corneal stromal nub variable in location with abnormal extracellular matrix.					
35131519	6	77	dep	RESULTS	682:688	arg1	appeared					712:719	appeared	712:719	appeared	712:719	RESULTS Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stroma, lined in some instances, by Descemet membrane.					
35131519	12	78	from	variability	1842:1852	arg1	intensity					1866:1874	staining intensity	1857:1874	staining intensity	1857:1874	Immunohistochemical examination revealed that the composition of PE's extracellular matrix was similar to corneal stroma but with some variability in staining intensity.					
35131519	11	79	theme	accepted	1425:1432	arg1	definition					1434:1443	the widely accepted definition	1414:1443	the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line	1414:1500	CONCLUSIONS In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalbe's line.					
37028623	2	0	theme	absorption	491:500	arg1	kinetics					502:509	absorption kinetics	491:509	absorption kinetics of the developed film	491:531	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	9	1	used	used	1413:1416	arg2	film					1389:1392	this film	1384:1392	this film	1384:1392	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	9	1	used	used	1413:1416	arg2	layer					1453:1457	a UV-blocking layer	1439:1457	a UV-blocking layer with potential biodegradability and good moisture resistance	1439:1518	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	1	2	theme	different	268:276	arg1	concentrations					278:291	different concentrations	268:291	different concentrations of titanium dioxide (TiO2)	268:318	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	5	3	link	crosslinked	858:868	arg1	film					870:873	crosslinked film	858:873	crosslinked film	858:873	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	7	4	theme	absorption	1042:1051	arg1	study					1061:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	5	5	theme	crosslinked	858:868	arg1	film					870:873	crosslinked film	858:873	crosslinked film	858:873	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	6	6	theme	films	949:953	arg1	Surface					924:930	Surface	924:930	Surface of the developed films	924:953	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	7	7	theme	correlation	1166:1176	arg1	coefficient					1178:1188	a correlation coefficient ≥0.99	1164:1194	a correlation coefficient ≥0.99	1164:1194	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	9	8	theme	flax	1540:1543	arg1	mucilage					1550:1557	pure flax seed mucilage	1535:1557	pure flax seed mucilage	1535:1557	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	4	9	theme	>21 days	797:804	arg1	biodegradation					779:792	biodegradation	779:792	biodegradation of >21 days	779:804	Crosslinking agent and TiO2 resulted in a prolonged period of biodegradation of >21 days when compared to neat film.					
37028623	5	10	theme	films	917:921	arg1	times					892:896	3 times	890:896	3 times of non-crosslinked films	890:921	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	6	11	contain	has	955:957	arg2	cracks					962:967	no cracks	959:967	no cracks	959:967	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	6	11	contain	has	955:957	arg1	Surface					924:930	Surface	924:930	Surface of the developed films	924:953	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	6	12	theme	developed	939:947	arg1	films					949:953	the developed films	935:953	the developed films	935:953	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	0	13	theme	calcium	103:109	arg1	chloride					111:118	calcium chloride	103:118	calcium chloride	103:118	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	8	14	with	film	1257:1260	arg1	TiO2					1273:1276	1 wt% TiO2	1267:1276	1 wt% TiO2	1267:1276	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	14	with	film	1257:1260	arg1	CaCl2					1288:1292	5 wt% CaCl2	1282:1292	5 wt% CaCl2	1282:1292	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	7	15	dep	model	1153:1157	arg1	controlled					1213:1222	controlled	1213:1222	was controlled by inter-particle diffusion	1209:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	1	16	theme	titanium	296:303	arg1	TiO2					314:317	TiO2	314:317	TiO2	314:317	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	1	16	theme	titanium	296:303	arg1	dioxide					305:311	titanium dioxide	296:311	titanium dioxide (TiO2)	296:318	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	2	17	theme	developed	518:526	arg1	film					528:531	the developed film	514:531	the developed film	514:531	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	8	18	theme	1 wt	1267:1270	arg1	TiO2					1273:1276	1 wt% TiO2	1267:1276	1 wt% TiO2	1267:1276	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	7	19	theme	pseudo-second-order	1125:1143	arg1	model					1153:1157	a pseudo-second-order kinetic model	1123:1157	a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion	1123:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	8	20	theme	rate	1312:1315	arg1	k1					1328:1329	k1	1328:1329	k1	1328:1329	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	20	theme	rate	1312:1315	arg1	constants					1317:1325	the lowest rate constants	1301:1325	the lowest rate constants (k1) of 0.27 and (k2) of 0.029	1301:1356	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	1	21	theme	biodegradable	183:195	arg1	films					207:211	potentially biodegradable composite films	171:211	potentially biodegradable composite films	171:211	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	9	22	with	layer	1453:1457	arg1	resistance					1509:1518	good moisture resistance	1495:1518	good moisture resistance	1495:1518	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	9	22	with	layer	1453:1457	arg1	biodegradability					1474:1489	potential biodegradability	1464:1489	potential biodegradability	1464:1489	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	3	23	from	%	714:714	arg1	%					702:702	54.1 %	697:702	54.1 % from 43.6 %	697:714	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	7	24	theme	Moisture	1033:1040	arg1	study					1061:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	8	25	theme	lowest	1305:1310	arg1	k1					1328:1329	k1	1328:1329	k1	1328:1329	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	25	theme	lowest	1305:1310	arg1	constants					1317:1325	the lowest rate constants	1301:1325	the lowest rate constants (k1) of 0.27 and (k2) of 0.029	1301:1356	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	26	theme	0.27	1335:1338	arg1	k1					1328:1329	k1	1328:1329	k1	1328:1329	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	26	theme	0.27	1335:1338	arg1	constants					1317:1325	the lowest rate constants	1301:1325	the lowest rate constants (k1) of 0.27 and (k2) of 0.029	1301:1356	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	1	27	theme	composite	197:205	arg1	films					207:211	potentially biodegradable composite films	171:211	potentially biodegradable composite films	171:211	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	0	28	theme	biodegradable	12:24	arg1	film					26:29	UV-blocking biodegradable film	0:29	UV-blocking biodegradable film	0:29	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	4	29	theme	neat	823:826	arg1	film					828:831	neat film	823:831	neat film	823:831	Crosslinking agent and TiO2 resulted in a prolonged period of biodegradation of >21 days when compared to neat film.					
37028623	0	30	theme	UV-blocking	0:10	arg1	film					26:29	UV-blocking biodegradable film	0:29	UV-blocking biodegradable film	0:29	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	1	31	theme	dioxide	305:311	arg1	concentrations					278:291	different concentrations	268:291	different concentrations of titanium dioxide (TiO2)	268:318	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	7	32	theme	kinetic	1053:1059	arg1	study					1061:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study	1033:1065	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	3	33	theme	5 wt	574:577	arg1	TiO2					580:583	5 wt% TiO2	574:583	5 wt% TiO2	574:583	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	6	34	theme	electron	1012:1019	arg1	microscope					1021:1030	scanning electron microscope	1003:1030	scanning electron microscope	1003:1030	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	8	35	theme	0.029	1352:1356	arg1	0.27					1335:1338	0.27	1335:1338	0.27	1335:1338	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	35	theme	0.029	1352:1356	arg1	k2					1345:1346	k2	1345:1346	k2	1345:1346	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	35	theme	0.029	1352:1356	arg1	0.029					1352:1356	0.029	1352:1356	0.029	1352:1356	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	8	36	theme	%	1271:1271	arg1	TiO2					1273:1276	1 wt% TiO2	1267:1276	1 wt% TiO2	1267:1276	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	4	37	theme	Crosslinking	717:728	arg1	agent					730:734	Crosslinking agent	717:734	Crosslinking agent	717:734	Crosslinking agent and TiO2 resulted in a prolonged period of biodegradation of >21 days when compared to neat film.					
37028623	4	38	theme	biodegradation	779:792	arg1	period					769:774	a prolonged period	757:774	a prolonged period of biodegradation of >21 days	757:804	Crosslinking agent and TiO2 resulted in a prolonged period of biodegradation of >21 days when compared to neat film.					
37028623	6	39	theme	scanning	1003:1010	arg1	microscope					1021:1030	scanning electron microscope	1003:1030	scanning electron microscope	1003:1030	Surface of the developed films has no cracks and agglomerates as observed from scanning electron microscope.					
37028623	2	40	theme	optical	423:429	arg1	kinetics					502:509	absorption kinetics	491:509	absorption kinetics of the developed film	491:531	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	2	40	theme	optical	423:429	arg1	color					452:456	color	452:456	color	452:456	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	2	40	theme	optical	423:429	arg1	biodegradability					469:484	potential biodegradability	459:484	potential biodegradability	459:484	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	2	40	theme	optical	423:429	arg1	properties					431:440	the physical, surface, and optical properties	396:440	properties	431:440	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	0	41	theme	packaging	129:137	arg1	applications					139:150	food packaging applications	124:150	food packaging applications	124:150	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	5	42	theme	non-crosslinked	901:915	arg1	films					917:921	non-crosslinked films	901:921	non-crosslinked films	901:921	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	5	43	theme	swelling	840:847	arg1	index					849:853	swelling index	840:853	swelling index of crosslinked film	840:873	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	0	44	theme	flaxseed	40:47	arg1	mucilage/pectin					49:63	flaxseed mucilage/pectin	40:63	flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications	40:150	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	8	45	theme	%	1286:1286	arg1	CaCl2					1288:1292	5 wt% CaCl2	1282:1292	5 wt% CaCl2	1282:1292	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	0	46	theme	food	124:127	arg1	applications					139:150	food packaging applications	124:150	food packaging applications	124:150	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	1	47	theme	flax	233:236	arg1	mucilage					243:250	flax seed mucilage	233:250	flax seed mucilage	233:250	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	2	48	theme	physical	400:407	arg1	surface					410:416	the physical, surface, and optical properties	396:440	surface	410:416	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	3	49	theme	total	621:625	arg1	change					633:638	a total color change	619:638	a total color change (ΔE) of 23.441 ± 0.54	619:660	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	3	49	theme	total	621:625	arg1	ΔE					641:642	ΔE	641:642	ΔE	641:642	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	3	50	theme	UV	594:595	arg1	property					605:612	UV barrier property	594:612	UV barrier property	594:612	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	9	51	theme	seed	1545:1548	arg1	mucilage					1550:1557	pure flax seed mucilage	1535:1557	pure flax seed mucilage	1535:1557	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	1	52	theme	seed	238:241	arg1	mucilage					243:250	flax seed mucilage	233:250	flax seed mucilage	233:250	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	2	53	theme	potential	459:467	arg1	biodegradability					469:484	potential biodegradability	459:484	potential biodegradability	459:484	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	3	54	theme	color	627:631	arg1	change					633:638	a total color change	619:638	a total color change (ΔE) of 23.441 ± 0.54	619:660	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	3	54	theme	color	627:631	arg1	ΔE					641:642	ΔE	641:642	ΔE	641:642	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	3	55	theme	%	578:578	arg1	TiO2					580:583	5 wt% TiO2	574:583	5 wt% TiO2	574:583	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	5	56	theme	film	870:873	arg1	index					849:853	swelling index	840:853	swelling index of crosslinked film	840:873	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	7	57	theme	best-fit	1099:1106	arg1	data					1108:1111	best-fit data	1099:1111	best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion	1099:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	9	58	theme	UV-blocking	1441:1451	arg1	film					1389:1392	this film	1384:1392	this film	1384:1392	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	9	58	theme	UV-blocking	1441:1451	arg1	layer					1453:1457	a UV-blocking layer	1439:1457	a UV-blocking layer with potential biodegradability and good moisture resistance	1439:1518	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	3	59	theme	TiO2	580:583	arg1	addition					562:569	addition	562:569	addition of 5 wt% TiO2	562:583	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	9	60	theme	pectin	1562:1567	arg1	films					1569:1573	pectin films	1562:1573	pectin films	1562:1573	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	1	61	theme	calcium	341:347	arg1	CaCl2					359:363	CaCl2	359:363	CaCl2	359:363	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	1	61	theme	calcium	341:347	arg1	chloride					349:356	calcium chloride	341:356	calcium chloride (CaCl2)	341:364	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	3	62	theme	23.441 ± 0.54	648:660	arg1	change					633:638	a total color change	619:638	a total color change (ΔE) of 23.441 ± 0.54	619:660	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	3	62	theme	23.441 ± 0.54	648:660	arg1	ΔE					641:642	ΔE	641:642	ΔE	641:642	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	9	63	theme	pure	1535:1538	arg1	mucilage					1550:1557	pure flax seed mucilage	1535:1557	pure flax seed mucilage	1535:1557	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	7	64	contain	have	1094:1097	arg2	data					1108:1111	best-fit data	1099:1111	best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion	1099:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	7	64	contain	have	1094:1097	arg1	films					1088:1092	all the films	1080:1092	all the films	1080:1092	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	9	65	theme	moisture	1500:1507	arg1	resistance					1509:1518	good moisture resistance	1495:1518	good moisture resistance	1495:1518	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	9	66	theme	good	1495:1498	arg1	resistance					1509:1518	good moisture resistance	1495:1518	good moisture resistance	1495:1518	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	9	67	theme	potential	1464:1472	arg1	biodegradability					1474:1489	potential biodegradability	1464:1489	potential biodegradability	1464:1489	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	8	68	theme	5 wt	1282:1285	arg1	CaCl2					1288:1292	5 wt% CaCl2	1282:1292	5 wt% CaCl2	1282:1292	The film with 1 wt% TiO2 and 5 wt% CaCl2 showed the lowest rate constants (k1) of 0.27 and (k2) of 0.029.					
37028623	7	69	theme	inter-particle	1227:1240	arg1	diffusion					1242:1250	inter-particle diffusion	1227:1250	inter-particle diffusion	1227:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	0	70	theme	titanium	82:89	arg1	dioxide					91:97	titanium dioxide	82:97	titanium dioxide	82:97	UV-blocking biodegradable film based on flaxseed mucilage/pectin impregnated with titanium dioxide and calcium chloride for food packaging applications.					
37028623	3	71	theme	barrier	597:603	arg1	property					605:612	UV barrier property	594:612	UV barrier property	594:612	From the observations made, addition of 5 wt% TiO2 enhanced UV barrier property with a total color change (ΔE) of 23.441 ± 0.54 and increased its crystallinity to 54.1 % from 43.6 %.					
37028623	9	72	theme	food	1421:1424	arg1	packaging					1426:1434	food packaging	1421:1434	food packaging	1421:1434	The results suggest that this film can be potentially used in food packaging as a UV-blocking layer with potential biodegradability and good moisture resistance as compared to pure flax seed mucilage or pectin films.					
37028623	1	73	theme	UV	155:156	arg1	blocking					158:165	A UV blocking	153:165	A UV blocking	153:165	A UV blocking and potentially biodegradable composite films are fabricated from flax seed mucilage and pectin with different concentrations of titanium dioxide (TiO2) and crosslinked with calcium chloride (CaCl2).					
37028623	5	74	link	non-crosslinked	901:915	arg1	films					917:921	non-crosslinked films	901:921	non-crosslinked films	901:921	Also, swelling index of crosslinked film was reduced by 3 times of non-crosslinked films.					
37028623	4	75	theme	prolonged	759:767	arg1	period					769:774	a prolonged period	757:774	a prolonged period of biodegradation of >21 days	757:804	Crosslinking agent and TiO2 resulted in a prolonged period of biodegradation of >21 days when compared to neat film.					
37028623	7	76	theme	kinetic	1145:1151	arg1	model					1153:1157	a pseudo-second-order kinetic model	1123:1157	a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion	1123:1250	Moisture absorption kinetic study reveals that all the films have best-fit data following a pseudo-second-order kinetic model with a correlation coefficient ≥0.99 and the rate was controlled by inter-particle diffusion.					
37028623	2	77	theme	film	528:531	arg1	kinetics					502:509	absorption kinetics	491:509	absorption kinetics of the developed film	491:531	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	2	77	theme	film	528:531	arg1	color					452:456	color	452:456	color	452:456	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
37028623	2	77	theme	film	528:531	arg1	biodegradability					469:484	potential biodegradability	459:484	potential biodegradability	459:484	This study aimed to evaluate the physical, surface, and optical properties including color, potential biodegradability, and absorption kinetics of the developed film.					
35802969	0	0	theme	moisture	82:89	arg1	foods					91:95	sucrose-rich and low moisture foods	61:95	sucrose-rich and low moisture foods	61:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	1	1	theme	amino	323:327	arg1	acid					329:332	amino acid	323:332	amino acid	323:332	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	4	2	theme	sugar	838:842	arg1	degradation					844:854	sugar degradation	838:854	sugar degradation	838:854	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	5	3	theme	lysine	1216:1221	arg1	residue					1223:1229	lysine residue	1216:1229	lysine residue	1216:1229	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	0	4	theme	low	78:80	arg1	foods					91:95	sucrose-rich and low moisture foods	61:95	sucrose-rich and low moisture foods	61:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	0	5	from	modeling	8:15	arg1	foods					91:95	sucrose-rich and low moisture foods	61:95	sucrose-rich and low moisture foods	61:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	2	6	theme	seed	562:565	arg1	roasting					526:533	roasting	526:533	roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond	526:595	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	7	theme	acids	456:460	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	5	8	theme	N-ε-fructoselysine	1158:1175	arg1	oxidation					1145:1153	oxidation	1145:1153	oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively	1145:1243	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	3	9	from	difference	684:693	arg1	compositional					698:710	compositional	698:710	compositional	698:710	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	3	9	from	difference	684:693	arg1	characteristics					732:746	physicochemical characteristics	716:746	physicochemical characteristics	716:746	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	2	10	theme	Maillard	487:494	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	3	11	theme	different	627:635	arg1	model					637:641	A slightly different model	616:641	A slightly different model	616:641	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	2	12	theme	pumpkin	554:560	arg1	seed					562:565	pumpkin seed	554:565	pumpkin seed	554:565	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	13	theme	low	258:260	arg1	foods					271:275	low moisture foods	258:275	low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	258:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	14	theme	sucrose	338:344	arg1	acid					329:332	amino acid	323:332	amino acid	323:332	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	14	theme	sucrose	338:344	arg1	sucrose					338:344	sucrose	338:344	sucrose	338:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	14	theme	sucrose	338:344	arg1	amount					313:318	a moderate amount	302:318	a moderate amount of amino acid and sucrose	302:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	2	15	theme	almond	590:595	arg1	roasting					526:533	roasting	526:533	roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond	526:595	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	16	theme	moisture	262:269	arg1	foods					271:275	low moisture foods	258:275	low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	258:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	0	17	theme	roasted	109:115	arg1	nuts					117:120	roasted nuts	109:120	roasted nuts	109:120	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	3	18	dep	compositional	698:710	arg1	expressed					751:759	expressed	751:759	expressed by principal component analysis	751:791	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	3	19	theme	principal	764:772	arg1	analysis					784:791	principal component analysis	764:791	principal component analysis	764:791	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	2	20	theme	protein-bound	423:435	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	21	theme	amino	450:454	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	22	from	pH	288:289	arg1	foods					271:275	low moisture foods	258:275	low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	258:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	22	from	pH	288:289	arg1	reactions					245:253	Maillard and caramelization reactions	217:253	reactions	245:253	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	0	23	theme	Kinetic	0:6	arg1	modeling					8:15	Kinetic modeling	0:15	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods	0:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	4	24	theme	pumpkin	925:931	arg1	seeds					933:937	pumpkin seeds	925:937	pumpkin seeds	925:937	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	2	25	theme	products	475:482	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	25	theme	products	475:482	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	25	theme	products	475:482	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	25	theme	products	475:482	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	25	theme	products	475:482	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	25	theme	products	475:482	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	26	theme	restricted	352:361	arg1	amount					363:368	a restricted amount	350:368	a restricted amount reducing sugar	350:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	4	27	theme	5-hydroxymethylfurfural	857:879	arg1	formation					881:889	5-hydroxymethylfurfural formation	857:889	5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal	857:985	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	1	28	theme	acid	329:332	arg1	acid					329:332	amino acid	323:332	amino acid	323:332	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	28	theme	acid	329:332	arg1	sucrose					338:344	sucrose	338:344	sucrose	338:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	28	theme	acid	329:332	arg1	amount					313:318	a moderate amount	302:318	a moderate amount of amino acid and sucrose	302:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	2	29	theme	flaxseed	568:575	arg1	roasting					526:533	roasting	526:533	roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond	526:595	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	0	30	theme	Maillard	20:27	arg1	reactions					48:56	Maillard and caramelization reactions	20:56	reactions	48:56	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	3	31	theme	component	774:782	arg1	analysis					784:791	principal component analysis	764:791	principal component analysis	764:791	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	1	32	theme	multiresponse	173:185	arg1	approach					204:211	a multiresponse kinetic modeling approach	171:211	a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	171:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	2	33	theme	free	445:448	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	34	theme	neutral	280:286	arg1	pH					288:289	neutral pH	280:289	neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	280:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	2	35	theme	sucrose	414:420	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	35	theme	sucrose	414:420	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	35	theme	sucrose	414:420	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	35	theme	sucrose	414:420	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	35	theme	sucrose	414:420	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	35	theme	sucrose	414:420	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	36	contain	containing	291:300	arg2	amount					313:318	a moderate amount	302:318	a moderate amount of amino acid and sucrose	302:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	36	contain	containing	291:300	arg2	amount					363:368	a restricted amount	350:368	a restricted amount reducing sugar	350:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	36	contain	containing	291:300	arg1	pH					288:289	neutral pH	280:289	neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	280:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	36	contain	containing	291:300	arg2	sucrose					338:344	sucrose	338:344	sucrose	338:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	36	contain	containing	291:300	arg2	acid					329:332	amino acid	323:332	amino acid	323:332	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	37	theme	kinetic	187:193	arg1	approach					204:211	a multiresponse kinetic modeling approach	171:211	a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	171:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	0	38	theme	caramelization	33:46	arg1	reactions					48:56	Maillard and caramelization reactions	20:56	reactions	48:56	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	1	39	from	reactions	245:253	arg1	foods					271:275	low moisture foods	258:275	low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	258:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	39	from	reactions	245:253	arg1	pH					288:289	neutral pH	280:289	neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	280:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	40	theme	modeling	195:202	arg1	approach					204:211	a multiresponse kinetic modeling approach	171:211	a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar	171:383	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	4	41	theme	Heyns	991:995	arg1	product					997:1003	Heyns product	991:1003	Heyns product to 1-deoxyglucosone	991:1023	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	5	42	theme	methylglyoxal	1197:1209	arg1	N-ε-fructoselysine					1158:1175	N-ε-fructoselysine	1158:1175	N-ε-fructoselysine	1158:1175	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	5	42	theme	methylglyoxal	1197:1209	arg1	reaction					1185:1192	the reaction	1181:1192	the reaction of methylglyoxal with lysine residue	1181:1229	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	2	43	theme	reaction	496:503	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	43	theme	reaction	496:503	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	43	theme	reaction	496:503	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	43	theme	reaction	496:503	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	43	theme	reaction	496:503	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	43	theme	reaction	496:503	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	44	theme	certain	467:473	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	45	theme	lysine	437:442	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	3	46	theme	physicochemical	716:730	arg1	characteristics					732:746	physicochemical characteristics	716:746	physicochemical characteristics	716:746	A slightly different model was proposed for pumpkin seed due to its difference in compositional and physicochemical characteristics as expressed by principal component analysis.					
35802969	2	47	theme	seed	548:551	arg1	roasting					526:533	roasting	526:533	roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond	526:595	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	4	48	theme	N-ε-fructoselysine	957:974	arg1	conversion					943:952	the conversion	939:952	the conversion of N-ε-fructoselysine to glyoxal	939:985	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	4	48	theme	N-ε-fructoselysine	957:974	arg1	seeds					933:937	pumpkin seeds	925:937	pumpkin seeds	925:937	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	4	49	theme	3-deoxyglucosone	807:822	arg1	formation					824:832	3-deoxyglucosone formation	807:832	3-deoxyglucosone formation via sugar degradation	807:854	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	5	50	theme	reaction	1185:1192	arg1	oxidation					1145:1153	oxidation	1145:1153	oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively	1145:1243	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	0	51	theme	reactions	48:56	arg1	modeling					8:15	Kinetic modeling	0:15	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods	0:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	1	52	theme	moderate	304:311	arg1	acid					329:332	amino acid	323:332	amino acid	323:332	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	52	theme	moderate	304:311	arg1	sucrose					338:344	sucrose	338:344	sucrose	338:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	1	52	theme	moderate	304:311	arg1	amount					313:318	a moderate amount	302:318	a moderate amount of amino acid and sucrose	302:344	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	2	53	theme	sunflower	538:546	arg1	seed					548:551	sunflower seed	538:551	sunflower seed	538:551	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	4	54	from	3-deoxyglucosone	896:911	arg1	conversion					943:952	the conversion	939:952	the conversion of N-ε-fructoselysine to glyoxal	939:985	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	4	54	from	3-deoxyglucosone	896:911	arg1	seeds					933:937	pumpkin seeds	925:937	pumpkin seeds	925:937	Accordingly, 3-deoxyglucosone formation via sugar degradation; 5-hydroxymethylfurfural formation from 3-deoxyglucosone and only in pumpkin seeds the conversion of N-ε-fructoselysine to glyoxal and Heyns product to 1-deoxyglucosone were found to be quantitatively important.					
35802969	2	55	theme	peanut	578:583	arg1	roasting					526:533	roasting	526:533	roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond	526:595	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	5	56	with	N-ε-fructoselysine	1158:1175	arg1	residue					1223:1229	lysine residue	1216:1229	lysine residue	1216:1229	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	2	57	from	change	390:395	arg1	products					475:482	certain products	467:482	certain products	467:482	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	57	from	change	390:395	arg1	amount					404:409	the amount	400:409	the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction	400:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	57	from	change	390:395	arg1	sucrose					414:420	sucrose	414:420	sucrose	414:420	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	57	from	change	390:395	arg1	acids					456:460	free amino acids	445:460	free amino acids	445:460	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	57	from	change	390:395	arg1	reaction					496:503	Maillard reaction	487:503	Maillard reaction	487:503	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	2	57	from	change	390:395	arg1	lysine					437:442	protein-bound lysine	423:442	protein-bound lysine	423:442	The change in the amount of sucrose, protein-bound lysine, free amino acids, and certain products of Maillard reaction was monitored during roasting of sunflower seed, pumpkin seed, flaxseed, peanut, and almond at 160 and 180 °C.					
35802969	1	58	theme	Maillard	217:224	arg1	reactions					245:253	Maillard and caramelization reactions	217:253	reactions	245:253	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	0	59	theme	sucrose-rich	61:72	arg1	foods					91:95	sucrose-rich and low moisture foods	61:95	sucrose-rich and low moisture foods	61:95	Kinetic modeling of Maillard and caramelization reactions in sucrose-rich and low moisture foods applied for roasted nuts and seeds.					
35802969	1	60	theme	kinetic	135:141	arg1	model					143:147	A kinetic model	133:147	A kinetic model	133:147	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
35802969	5	61	with	reaction	1185:1192	arg1	residue					1223:1229	lysine residue	1216:1229	lysine residue	1216:1229	N-ε-carboxymethyllysine and N-ε-carboxyethyllysine mainly originated through oxidation of N-ε-fructoselysine and the reaction of methylglyoxal with lysine residue, respectively.					
35802969	1	62	theme	caramelization	230:243	arg1	reactions					245:253	Maillard and caramelization reactions	217:253	reactions	245:253	A kinetic model was proposed by using a multiresponse kinetic modeling approach for Maillard and caramelization reactions in low moisture foods at neutral pH containing a moderate amount of amino acid and sucrose but a restricted amount reducing sugar.					
37116842	1	0	theme	practical	382:390	arg1	implementation					392:405	the practical implementation	378:405	the practical implementation	378:405	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	8	1	theme	new	1384:1386	arg1	insight					1388:1394	new insight	1384:1394	new insight for modifying and fabricating electrode materials for practical CDI applications	1384:1475	This study may provide new insight for modifying and fabricating electrode materials for practical CDI applications.					
37116842	0	2	theme	carbon	103:108	arg1	aerogel					110:116	carboxymethyl cellulose carbon aerogel	79:116	carboxymethyl cellulose carbon aerogel	79:116	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	3	3	theme	particles	871:879	arg1	agglomeration					854:866	the agglomeration	850:866	the agglomeration of particles	850:879	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	0	4	theme	metal-organic	122:134	arg1	framework					136:144	metal-organic framework	122:144	metal-organic framework for capacitive deionization	122:172	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	4	5	from	carboxyl	904:911	arg1	CMC					936:938	CMC	936:938	CMC	936:938	Furthermore, numerous carboxyl and hydroxyl groups on CMC enhanced the hydrophilicity of materials.					
37116842	3	6	theme	ZIF-8	576:580	arg1	presence					564:571	The presence	560:571	The presence of ZIF-8	560:580	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	6	7	theme	three-electrode	1169:1183	arg1	system					1185:1190	a three-electrode system	1167:1190	a three-electrode system	1167:1190	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	1	8	theme	low	303:305	arg1	rate					323:326	the low salt adsorption rate	299:326	the low salt adsorption rate of benchmark carbon materials	299:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	8	9	theme	electrode	1426:1434	arg1	materials					1436:1444	electrode materials	1426:1444	electrode materials	1426:1444	This study may provide new insight for modifying and fabricating electrode materials for practical CDI applications.					
37116842	4	10	theme	hydroxyl	917:924	arg1	groups					926:931	numerous carboxyl and hydroxyl groups	895:931	groups	926:931	Furthermore, numerous carboxyl and hydroxyl groups on CMC enhanced the hydrophilicity of materials.					
37116842	5	11	theme	excellent	1042:1050	arg1	conductivity					1052:1063	excellent conductivity	1042:1063	excellent conductivity	1042:1063	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	11	theme	excellent	1042:1050	arg1	area					1090:1093	a high specific surface area	1066:1093	a high specific surface area	1066:1093	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	1	12	theme	salt	307:310	arg1	rate					323:326	the low salt adsorption rate	299:326	the low salt adsorption rate of benchmark carbon materials	299:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	2	13	used	utilized	419:426	arg2	we					416:417	we	416:417	we	416:417	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	6	14	theme	specific	1203:1210	arg1	capacitance					1212:1222	the total specific capacitance	1193:1222	the total specific capacitance of the ZIF-8/CMC-CA electrode	1193:1252	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	6	14	theme	specific	1203:1210	arg1	357.14 F g-1					1258:1269	357.14 F g-1	1258:1269	357.14 F g-1	1258:1269	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	6	15	theme	electrode	1244:1252	arg1	capacitance					1212:1222	the total specific capacitance	1193:1222	the total specific capacitance of the ZIF-8/CMC-CA electrode	1193:1252	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	6	15	theme	electrode	1244:1252	arg1	357.14 F g-1					1258:1269	357.14 F g-1	1258:1269	357.14 F g-1	1258:1269	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	7	16	from	2.02 mg g-1 min-1	1312:1328	arg1	solution					1351:1358	a 500 mg L-1 NaCl solution	1333:1358	a 500 mg L-1 NaCl solution	1333:1358	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	5	17	dep	entry	1140:1144	arg1	the					1130:1132	the	1130:1132	the	1130:1132	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	8	18	theme	CDI	1460:1462	arg1	applications					1464:1475	practical CDI applications	1450:1475	practical CDI applications	1450:1475	This study may provide new insight for modifying and fabricating electrode materials for practical CDI applications.					
37116842	1	19	theme	porous	211:216	arg1	materials					218:226	porous materials	211:226	porous materials	211:226	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	3	20	theme	good	766:769	arg1	structure					789:797	a good three-dimensional structure	764:797	a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles	764:839	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	4	21	theme	numerous	895:902	arg1	carboxyl					904:911	numerous carboxyl and hydroxyl groups	895:931	carboxyl	904:911	Furthermore, numerous carboxyl and hydroxyl groups on CMC enhanced the hydrophilicity of materials.					
37116842	3	22	theme	three-dimensional	771:787	arg1	structure					789:797	a good three-dimensional structure	764:797	a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles	764:839	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	23	theme	pore	609:612	arg1	structure					614:622	the pore structure	605:622	the pore structure of the material	605:638	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	2	24	theme	cellulose	442:450	arg1	sodium					452:457	carboxymethyl cellulose sodium	428:457	carboxymethyl cellulose sodium (CMC)	428:463	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	2	24	theme	cellulose	442:450	arg1	skeleton					479:486	the carbon skeleton	468:486	the carbon skeleton	468:486	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	2	24	theme	cellulose	442:450	arg1	CMC					460:462	CMC	460:462	CMC	460:462	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	1	25	theme	adsorption	312:321	arg1	rate					323:326	the low salt adsorption rate	299:326	the low salt adsorption rate of benchmark carbon materials	299:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	7	26	theme	adsorption	1276:1285	arg1	rate					1287:1290	The adsorption rate	1272:1290	The adsorption rate of ZIF-8/CMC-CA	1272:1306	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	7	26	theme	adsorption	1276:1285	arg1	2.02 mg g-1 min-1					1312:1328	2.02 mg g-1 min-1	1312:1328	2.02 mg g-1 min-1	1312:1328	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	2	27	theme	carboxymethyl	428:440	arg1	sodium					452:457	carboxymethyl cellulose sodium	428:457	carboxymethyl cellulose sodium (CMC)	428:463	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	2	27	theme	carboxymethyl	428:440	arg1	skeleton					479:486	the carbon skeleton	468:486	the carbon skeleton	468:486	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	2	27	theme	carboxymethyl	428:440	arg1	CMC					460:462	CMC	460:462	CMC	460:462	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	0	28	theme	hierarchical	39:50	arg1	carbon					59:64	heteroatom-doped hierarchical porous carbon	22:64	heteroatom-doped hierarchical porous carbon	22:64	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	5	29	theme	high	1068:1071	arg1	conductivity					1052:1063	excellent conductivity	1042:1063	excellent conductivity	1042:1063	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	29	theme	high	1068:1071	arg1	area					1090:1093	a high specific surface area	1066:1093	a high specific surface area	1066:1093	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	2	30	theme	carbon	472:477	arg1	sodium					452:457	carboxymethyl cellulose sodium	428:457	carboxymethyl cellulose sodium (CMC)	428:463	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	2	30	theme	carbon	472:477	arg1	skeleton					479:486	the carbon skeleton	468:486	the carbon skeleton	468:486	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	0	31	theme	capacitive	150:159	arg1	deionization					161:172	capacitive deionization	150:172	capacitive deionization	150:172	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	4	32	theme	materials	971:979	arg1	hydrophilicity					953:966	the hydrophilicity	949:966	the hydrophilicity of materials	949:979	Furthermore, numerous carboxyl and hydroxyl groups on CMC enhanced the hydrophilicity of materials.					
37116842	5	33	theme	interconnected	993:1006	arg1	structure					1008:1016	the interconnected structure	989:1016	the interconnected structure	989:1016	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	1	34	theme	sustainable	237:247	arg1	solution					249:256	a sustainable solution	235:256	a sustainable solution for providing affordable freshwater	235:292	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	0	35	theme	carbon	59:64	arg1	Nanoarchitectonics					0:17	Nanoarchitectonics	0:17	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon	0:64	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	1	36	theme	benchmark	331:339	arg1	materials					348:356	benchmark carbon materials	331:356	benchmark carbon materials	331:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	3	37	theme	material	631:638	arg1	structure					614:622	the pore structure	605:622	the pore structure of the material	605:638	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	7	38	theme	NaCl	1346:1349	arg1	solution					1351:1358	a 500 mg L-1 NaCl solution	1333:1358	a 500 mg L-1 NaCl solution	1333:1358	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	0	39	theme	porous	52:57	arg1	carbon					59:64	heteroatom-doped hierarchical porous carbon	22:64	heteroatom-doped hierarchical porous carbon	22:64	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	1	40	theme	carbon	341:346	arg1	materials					348:356	benchmark carbon materials	331:356	benchmark carbon materials	331:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	2	41	theme	carbon	511:516	arg1	aerogel					518:524	a composite carbon aerogel	499:524	a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA)	499:557	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	5	42	theme	specific	1073:1080	arg1	conductivity					1052:1063	excellent conductivity	1042:1063	excellent conductivity	1042:1063	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	42	theme	specific	1073:1080	arg1	area					1090:1093	a high specific surface area	1066:1093	a high specific surface area	1066:1093	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	2	43	theme	composite	501:509	arg1	aerogel					518:524	a composite carbon aerogel	499:524	a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA)	499:557	Herein, we utilized carboxymethyl cellulose sodium (CMC) as the carbon skeleton to produce a composite carbon aerogel loaded with ZIF-8 (ZIF-8/CMC-CA).					
37116842	1	44	theme	materials	348:356	arg1	rate					323:326	the low salt adsorption rate	299:326	the low salt adsorption rate of benchmark carbon materials	299:356	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	5	45	theme	rapid	1134:1138	arg1	entry					1140:1144	rapid entry	1134:1144	rapid entry	1134:1144	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	46	theme	surface	1082:1088	arg1	conductivity					1052:1063	excellent conductivity	1042:1063	excellent conductivity	1042:1063	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	46	theme	surface	1082:1088	arg1	area					1090:1093	a high specific surface area	1066:1093	a high specific surface area	1066:1093	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	3	47	dep	nanoparticles	582:594	arg1	improved					596:603	improved	596:603	nanoparticles improved the pore structure of the material	582:638	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	48	dep	CMC	751:753	arg1	provided					755:762	provided	755:762	provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles	755:839	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	5	49	theme	ions	1158:1161	arg1	exit					1150:1153	exit	1150:1153	exit	1150:1153	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	5	49	theme	ions	1158:1161	arg1	entry					1140:1144	rapid entry	1134:1144	rapid entry	1134:1144	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	7	50	theme	500 mg L-1	1335:1344	arg1	solution					1351:1358	a 500 mg L-1 NaCl solution	1333:1358	a 500 mg L-1 NaCl solution	1333:1358	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	3	51	dep	provided	755:762	arg1	reduced					842:848	reduced	842:848	reduced the agglomeration of particles	842:879	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	52	theme	derived	720:726	arg1	ZIF-8-C					737:743	ZIF-8-C	737:743	ZIF-8-C	737:743	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	52	theme	derived	720:726	arg1	carbons					728:734	ZIF-8 derived carbons	714:734	ZIF-8 derived carbons (ZIF-8-C)	714:744	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	52	theme	derived	720:726	arg1	CMC					751:753	the CMC	747:753	the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles	747:879	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	53	theme	certain	655:661	arg1	capacitance					670:680	a certain pseudo capacitance	653:680	a certain pseudo capacitance	653:680	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	8	54	theme	practical	1450:1458	arg1	applications					1464:1475	practical CDI applications	1450:1475	practical CDI applications	1450:1475	This study may provide new insight for modifying and fabricating electrode materials for practical CDI applications.					
37116842	6	55	from	357.14 F g-1	1258:1269	arg1	system					1185:1190	a three-electrode system	1167:1190	a three-electrode system	1167:1190	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	6	56	theme	total	1197:1201	arg1	capacitance					1212:1222	the total specific capacitance	1193:1222	the total specific capacitance of the ZIF-8/CMC-CA electrode	1193:1252	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	6	56	theme	total	1197:1201	arg1	357.14 F g-1					1258:1269	357.14 F g-1	1258:1269	357.14 F g-1	1258:1269	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	3	57	theme	pseudo	663:668	arg1	capacitance					670:680	a certain pseudo capacitance	653:680	a certain pseudo capacitance	653:680	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	1	58	theme	Capacitive	175:184	arg1	CDI					200:202	CDI	200:202	CDI	200:202	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	1	58	theme	Capacitive	175:184	arg1	deionization					186:197	Capacitive deionization	175:197	Capacitive deionization (CDI) using porous materials	175:226	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	1	59	theme	affordable	272:281	arg1	freshwater					283:292	affordable freshwater	272:292	affordable freshwater	272:292	Capacitive deionization (CDI) using porous materials offers a sustainable solution for providing affordable freshwater, but the low salt adsorption rate of benchmark carbon materials significantly limit the practical implementation.					
37116842	0	60	theme	cellulose	93:101	arg1	aerogel					110:116	carboxymethyl cellulose carbon aerogel	79:116	carboxymethyl cellulose carbon aerogel	79:116	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	5	61	theme	suitable	1108:1115	arg1	channels					1117:1124	suitable channels	1108:1124	suitable channels for the rapid entry and exit of ions	1108:1161	Due to the interconnected structure, ZIF-8/CMC-CA exhibited excellent conductivity, a high specific surface area, and offered suitable channels for the rapid entry and exit of ions.					
37116842	6	62	theme	ZIF-8/CMC-CA	1231:1242	arg1	electrode					1244:1252	the ZIF-8/CMC-CA electrode	1227:1252	the ZIF-8/CMC-CA electrode	1227:1252	In a three-electrode system, the total specific capacitance of the ZIF-8/CMC-CA electrode was 357.14 F g-1.					
37116842	7	63	theme	ZIF-8/CMC-CA	1295:1306	arg1	rate					1287:1290	The adsorption rate	1272:1290	The adsorption rate of ZIF-8/CMC-CA	1272:1306	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	7	63	theme	ZIF-8/CMC-CA	1295:1306	arg1	2.02 mg g-1 min-1					1312:1328	2.02 mg g-1 min-1	1312:1328	2.02 mg g-1 min-1	1312:1328	The adsorption rate of ZIF-8/CMC-CA was 2.02 mg g-1 min-1 in a 500 mg L-1 NaCl solution.					
37116842	3	64	link	derived	720:726	arg1	ZIF-8-C					737:743	ZIF-8-C	737:743	ZIF-8-C	737:743	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	64	link	derived	720:726	arg1	carbons					728:734	ZIF-8 derived carbons	714:734	ZIF-8 derived carbons (ZIF-8-C)	714:744	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	64	link	derived	720:726	arg1	CMC					751:753	the CMC	747:753	the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles	747:879	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	3	65	theme	ZIF-8	821:825	arg1	nanoparticles					827:839	ZIF-8 nanoparticles	821:839	ZIF-8 nanoparticles	821:839	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
37116842	0	66	theme	carboxymethyl	79:91	arg1	aerogel					110:116	carboxymethyl cellulose carbon aerogel	79:116	carboxymethyl cellulose carbon aerogel	79:116	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	4	67	from	groups	926:931	arg1	CMC					936:938	CMC	936:938	CMC	936:938	Furthermore, numerous carboxyl and hydroxyl groups on CMC enhanced the hydrophilicity of materials.					
37116842	0	68	theme	heteroatom-doped	22:37	arg1	carbon					59:64	heteroatom-doped hierarchical porous carbon	22:64	heteroatom-doped hierarchical porous carbon	22:64	Nanoarchitectonics of heteroatom-doped hierarchical porous carbon derived from carboxymethyl cellulose carbon aerogel and metal-organic framework for capacitive deionization.					
37116842	3	69	theme	nanoparticles	827:839	arg1	dispersion					807:816	the dispersion	803:816	the dispersion of ZIF-8 nanoparticles	803:839	The presence of ZIF-8 nanoparticles improved the pore structure of the material and provides a certain pseudo capacitance by introducing N. Compared with ZIF-8 derived carbons (ZIF-8-C), the CMC provided a good three-dimensional structure for the dispersion of ZIF-8 nanoparticles, reduced the agglomeration of particles.					
36877072	15	0	dep	in	2374:2375	arg1	vivo					2377:2380	vivo	2377:2380	vivo	2377:2380	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	1	1	theme	coronavirus	266:276	arg1	disease					278:284	the worldwide coronavirus disease	252:284	the worldwide coronavirus disease 2019 (COVID-19) pandemic	252:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	8	2	theme	species-dependent	1003:1019	arg1	reticulum					1033:1041	species-dependent endoplasmic reticulum	1003:1041	species-dependent endoplasmic reticulum stress-like responses in human cells	1003:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	3	theme	reticulum	1033:1041	arg1	responses					1055:1063	species-dependent endoplasmic reticulum stress-like responses	1003:1063	species-dependent endoplasmic reticulum stress-like responses in human cells	1003:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	11	4	theme	virulence	1466:1474	arg1	gene					1476:1479	a key unique virulence gene	1453:1479	a key unique virulence gene of SARS-CoV-2	1453:1493	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	11	4	theme	virulence	1466:1474	arg1	ORF8					1438:1441	ORF8	1438:1441	ORF8	1438:1441	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	15	5	theme	ORF8	2407:2410	arg1	discrepancy					2392:2402	the superficially known in vivo virulence discrepancy	2350:2402	the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients	2350:2447	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	5	theme	ORF8	2407:2410	arg1	mouse					2453:2457	mouse	2453:2457	mouse	2453:2457	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	6	6	theme	human	825:829	arg1	calnexin					831:838	calnexin	831:838	calnexin	831:838	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36877072	2	7	theme	known	376:380	arg1	proteins					382:389	known proteins	376:389	known proteins	376:389	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	2	7	theme	known	376:380	arg1	proteins					412:419	accessory proteins	402:419	accessory proteins of other coronaviruses	402:442	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	5	8	theme	molecular	660:668	arg1	functions					670:678	the unbiased molecular functions	647:678	the unbiased molecular functions of ORF8	647:686	Here, the unbiased molecular functions of ORF8 are also demonstrated.					
36877072	9	9	theme	SARS-CoV-2	1280:1289	arg1	replication					1291:1301	SARS-CoV-2 replication	1280:1301	SARS-CoV-2 replication	1280:1301	ORF8 overexpression facilitates SARS-CoV-2 replication.					
36877072	2	10	theme	novel	316:320	arg1	homologous					360:369	homologous	360:369	homologous	360:369	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	2	10	theme	novel	316:320	arg1	protein					338:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	7	11	theme	ORF8-binding	859:870	arg1	Calnexin					881:888	Calnexin	881:888	Calnexin	881:888	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	11	theme	ORF8-binding	859:870	arg1	sites					872:876	The key ORF8-binding sites	851:876	The key ORF8-binding sites of Calnexin and HSPA5	851:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	11	theme	ORF8-binding	859:870	arg1	HSPA5					894:898	HSPA5	894:898	HSPA5	894:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	8	12	theme	human	1068:1072	arg1	cells					1074:1078	human cells	1068:1078	human cells	1068:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	14	13	theme	molecular	1962:1970	arg1	function					1972:1979	The molecular function	1958:1979	The molecular function of ORF8	1958:1987	The molecular function of ORF8 has not been clearly known until now.					
36877072	1	14	theme	viral	221:225	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	14	theme	viral	221:225	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	12	15	theme	genomic	1668:1674	arg1	structure					1676:1684	their genomic structure	1662:1684	their genomic structure	1662:1684	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	4	16	gly	glycosylation	590:602	arg1	site					635:638	the N78 site	627:638	the N78 site	627:638	Oligomannose-type glycosylation has been identified at the N78 site.					
36877072	10	17	theme	stress-like	1309:1319	arg1	responses					1321:1329	stress-like responses	1309:1329	stress-like responses	1309:1329	Both stress-like responses and viral replication induced by ORF8 have been shown to result from triggering the Calnexin switch.					
36877072	12	18	theme	SARS-CoV	1647:1654	arg1	homolog					1636:1642	a homolog	1634:1642	a homolog of SARS-CoV	1634:1654	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	12	18	theme	SARS-CoV	1647:1654	arg1	IMPORTANCE					1578:1587	IMPORTANCE	1578:1587	IMPORTANCE Although SARS-CoV-2	1578:1607	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	3	19	contain	contains	450:457	arg2	peptide					482:488	a 15-amino-acid signal peptide	459:488	a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum	459:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	3	19	contain	contains	450:457	arg1	ORF8					445:448	ORF8	445:448	ORF8	445:448	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	1	20	theme	acute	160:164	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	20	theme	acute	160:164	arg1	SARS-CoV-2					202:211	SARS-CoV-2	202:211	SARS-CoV-2	202:211	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	20	theme	acute	160:164	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	0	21	theme	Virus	92:96	arg1	Replication					98:108	Virus Replication	92:108	Virus Replication	92:108	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	1	22	theme	syndrome	178:185	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	22	theme	syndrome	178:185	arg1	SARS-CoV-2					202:211	SARS-CoV-2	202:211	SARS-CoV-2	202:211	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	22	theme	syndrome	178:185	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	8	23	from	increases	1168:1176	arg1	effectors					1205:1213	other stress-responding effectors	1181:1213	other stress-responding effectors	1181:1213	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	23	from	increases	1168:1176	arg1	CHOP					1226:1229	CHOP	1226:1229	CHOP	1226:1229	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	23	from	increases	1168:1176	arg1	DERL3					1241:1245	DERL3	1241:1245	DERL3	1241:1245	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	23	from	increases	1168:1176	arg1	EDEM					1232:1235	EDEM	1232:1235	EDEM	1232:1235	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	15	24	theme	protein	2108:2114	arg1	characteristics					2069:2083	the unbiased molecular characteristics	2046:2083	the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein	2046:2114	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	12	25	theme	ORF8	1747:1750	arg1	genes					1752:1756	the ORF8 genes	1743:1756	the ORF8 genes of SARS-CoV and SARS-CoV-2	1743:1783	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	12	25	theme	ORF8	1747:1750	arg1	distinct					1789:1796	distinct	1789:1796	distinct	1789:1796	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	2	26	theme	accessory	402:410	arg1	proteins					412:419	accessory proteins	402:419	accessory proteins of other coronaviruses	402:442	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	13	27	theme	host	1874:1877	arg1	proteins					1879:1886	host proteins	1874:1886	host proteins	1874:1886	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	15	28	theme	in	2374:2375	arg1	discrepancy					2392:2402	the superficially known in vivo virulence discrepancy	2350:2402	the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients	2350:2447	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	13	29	theme	SARS-CoV-2	1946:1955	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	29	theme	SARS-CoV-2	1946:1955	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	0	30	theme	SARS-CoV-2	0:9	arg1	Protein					16:22	SARS-CoV-2 ORF8 Protein	0:22	SARS-CoV-2 ORF8 Protein	0:22	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	7	31	theme	core	945:948	arg1	domain					968:973	the core substrate-binding domain	941:973	the core substrate-binding domain	941:973	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	11	32	theme	human-specific	1549:1562	arg1	pathogenesis					1564:1575	COVID-19-specific and/or human-specific pathogenesis	1524:1575	COVID-19-specific and/or human-specific pathogenesis	1524:1575	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	2	33	theme	coronaviruses	430:442	arg1	proteins					412:419	accessory proteins	402:419	accessory proteins of other coronaviruses	402:442	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	15	34	theme	known	2368:2372	arg1	discrepancy					2392:2402	the superficially known in vivo virulence discrepancy	2350:2402	the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients	2350:2447	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	13	35	theme	special	1920:1926	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	35	theme	special	1920:1926	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	11	36	theme	COVID-19-specific	1524:1540	arg1	pathogenesis					1564:1575	COVID-19-specific and/or human-specific pathogenesis	1524:1575	COVID-19-specific and/or human-specific pathogenesis	1524:1575	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	3	37	theme	15-amino-acid	461:473	arg1	peptide					482:488	a 15-amino-acid signal peptide	459:488	a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum	459:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	0	38	theme	Endoplasmic	32:42	arg1	Reticulum					44:52	Endoplasmic Reticulum	32:52	Endoplasmic Reticulum Stress-like Responses	32:74	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	8	39	theme	PDIA4	1143:1147	arg1	upregulation					1149:1160	PDIA4 upregulation	1143:1160	PDIA4 upregulation	1143:1160	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	15	40	theme	unbiased	2050:2057	arg1	characteristics					2069:2083	the unbiased molecular characteristics	2046:2083	the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein	2046:2114	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	10	41	theme	Calnexin	1415:1422	arg1	switch					1424:1429	the Calnexin switch	1411:1429	the Calnexin switch	1411:1429	Both stress-like responses and viral replication induced by ORF8 have been shown to result from triggering the Calnexin switch.					
36877072	0	42	theme	Stress-like	54:64	arg1	Responses					66:74	Endoplasmic Reticulum Stress-like Responses	32:74	Endoplasmic Reticulum Stress-like Responses	32:74	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	2	43	with	homologous	360:369	arg1	proteins					382:389	known proteins	376:389	known proteins	376:389	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	2	43	with	homologous	360:369	arg1	proteins					412:419	accessory proteins	402:419	accessory proteins of other coronaviruses	402:442	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	15	44	theme	controllable	2177:2188	arg1	responses					2224:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	45	theme	mouse	2308:2312	arg1	cells					2314:2318	mouse cells	2308:2318	human but not mouse cells	2294:2318	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	4	46	theme	N78	631:633	arg1	site					635:638	the N78 site	627:638	the N78 site	627:638	Oligomannose-type glycosylation has been identified at the N78 site.					
36877072	3	47	theme	mature	527:532	arg1	protein					534:540	the mature protein	523:540	the mature protein	523:540	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	15	48	theme	SARS-CoV-2-infected	2420:2438	arg1	patients					2440:2447	SARS-CoV-2-infected patients	2420:2447	SARS-CoV-2-infected patients	2420:2447	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	8	49	theme	other	1181:1185	arg1	effectors					1205:1213	other stress-responding effectors	1181:1213	other stress-responding effectors	1181:1213	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	49	theme	other	1181:1185	arg1	CHOP					1226:1229	CHOP	1226:1229	CHOP	1226:1229	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	49	theme	other	1181:1185	arg1	DERL3					1241:1245	DERL3	1241:1245	DERL3	1241:1245	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	49	theme	other	1181:1185	arg1	EDEM					1232:1235	EDEM	1232:1235	EDEM	1232:1235	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	1	50	theme	worldwide	256:264	arg1	disease					278:284	the worldwide coronavirus disease	252:284	the worldwide coronavirus disease 2019 (COVID-19) pandemic	252:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	8	51	theme	endoplasmic	1021:1031	arg1	reticulum					1033:1041	species-dependent endoplasmic reticulum	1003:1041	species-dependent endoplasmic reticulum stress-like responses in human cells	1003:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	52	from	responses	1055:1063	arg1	cells					1074:1078	human cells	1068:1078	human cells	1068:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	5	53	theme	ORF8	683:686	arg1	functions					670:678	the unbiased molecular functions	647:678	the unbiased molecular functions of ORF8	647:686	Here, the unbiased molecular functions of ORF8 are also demonstrated.					
36877072	3	54	theme	endoplasmic	549:559	arg1	reticulum					561:569	the endoplasmic reticulum	545:569	the endoplasmic reticulum	545:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	8	55	theme	stress-like	1043:1053	arg1	responses					1055:1063	species-dependent endoplasmic reticulum stress-like responses	1003:1063	species-dependent endoplasmic reticulum stress-like responses in human cells	1003:1078	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	11	56	theme	unique	1459:1464	arg1	gene					1476:1479	a key unique virulence gene	1453:1479	a key unique virulence gene of SARS-CoV-2	1453:1493	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	11	56	theme	unique	1459:1464	arg1	ORF8					1438:1441	ORF8	1438:1441	ORF8	1438:1441	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	9	57	theme	ORF8	1248:1251	arg1	overexpression					1253:1266	ORF8 overexpression	1248:1266	ORF8 overexpression	1248:1266	ORF8 overexpression facilitates SARS-CoV-2 replication.					
36877072	7	58	theme	HSPA5	894:898	arg1	Calnexin					881:888	Calnexin	881:888	Calnexin	881:888	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	58	theme	HSPA5	894:898	arg1	sites					872:876	The key ORF8-binding sites	851:876	The key ORF8-binding sites of Calnexin and HSPA5	851:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	58	theme	HSPA5	894:898	arg1	HSPA5					894:898	HSPA5	894:898	HSPA5	894:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	6	59	from	fold	738:741	arg1	manner					767:772	a glycan-independent manner	746:772	a glycan-independent manner	746:772	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36877072	13	60	theme	little	1838:1843	arg1	homology					1845:1852	little homology	1838:1852	little homology with other viral or host proteins	1838:1886	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	5	61	theme	unbiased	651:658	arg1	functions					670:678	the unbiased molecular functions	647:678	the unbiased molecular functions of ORF8	647:686	Here, the unbiased molecular functions of ORF8 are also demonstrated.					
36877072	2	62	theme	SARS-CoV-2	322:331	arg1	homologous					360:369	homologous	360:369	homologous	360:369	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	2	62	theme	SARS-CoV-2	322:331	arg1	protein					338:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	7	63	theme	Calnexin	881:888	arg1	Calnexin					881:888	Calnexin	881:888	Calnexin	881:888	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	63	theme	Calnexin	881:888	arg1	sites					872:876	The key ORF8-binding sites	851:876	The key ORF8-binding sites of Calnexin and HSPA5	851:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	63	theme	Calnexin	881:888	arg1	HSPA5					894:898	HSPA5	894:898	HSPA5	894:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	14	64	theme	ORF8	1984:1987	arg1	function					1972:1979	The molecular function	1958:1979	The molecular function of ORF8	1958:1987	The molecular function of ORF8 has not been clearly known until now.					
36877072	0	65	theme	Unbiased	137:144	arg1	Study					146:150	an Unbiased Study	134:150	an Unbiased Study	134:150	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	15	66	theme	virus	2250:2254	arg1	replication					2256:2266	virus replication	2250:2266	virus replication	2250:2266	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	12	67	theme	genes	1712:1716	arg1	homologous					1731:1740	homologous	1731:1740	homologous	1731:1740	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	12	67	theme	genes	1712:1716	arg1	majority					1694:1701	the majority	1690:1701	the majority of their genes	1690:1716	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	3	68	from	peptide	482:488	arg1	terminus					499:506	the N terminus	493:506	the N terminus that localizes the mature protein to the endoplasmic reticulum	493:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	13	69	theme	ORF8	1814:1817	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	69	theme	ORF8	1814:1817	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	7	70	theme	key	855:857	arg1	Calnexin					881:888	Calnexin	881:888	Calnexin	881:888	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	70	theme	key	855:857	arg1	sites					872:876	The key ORF8-binding sites	851:876	The key ORF8-binding sites of Calnexin and HSPA5	851:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	7	70	theme	key	855:857	arg1	HSPA5					894:898	HSPA5	894:898	HSPA5	894:898	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	1	71	theme	Severe	153:158	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	71	theme	Severe	153:158	arg1	SARS-CoV-2					202:211	SARS-CoV-2	202:211	SARS-CoV-2	202:211	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	71	theme	Severe	153:158	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	15	72	from	Calnexin	2282:2289	arg1	human					2294:2298	human	2294:2298	human	2294:2298	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	72	from	Calnexin	2282:2289	arg1	cells					2314:2318	mouse cells	2308:2318	human but not mouse cells	2294:2318	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	1	73	theme	respiratory	166:176	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	73	theme	respiratory	166:176	arg1	SARS-CoV-2					202:211	SARS-CoV-2	202:211	SARS-CoV-2	202:211	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	73	theme	respiratory	166:176	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	12	74	theme	SARS-CoV	1761:1768	arg1	genes					1752:1756	the ORF8 genes	1743:1756	the ORF8 genes of SARS-CoV and SARS-CoV-2	1743:1783	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	12	74	theme	SARS-CoV	1761:1768	arg1	distinct					1789:1796	distinct	1789:1796	distinct	1789:1796	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	10	75	theme	viral	1335:1339	arg1	replication					1341:1351	viral replication	1335:1351	viral replication	1335:1351	Both stress-like responses and viral replication induced by ORF8 have been shown to result from triggering the Calnexin switch.					
36877072	8	76	theme	IRE1	1100:1103	arg1	branch					1105:1110	the IRE1 branch	1096:1110	the IRE1 branch	1096:1110	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	12	77	theme	SARS-CoV-2	1774:1783	arg1	genes					1752:1756	the ORF8 genes	1743:1756	the ORF8 genes of SARS-CoV and SARS-CoV-2	1743:1783	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	12	77	theme	SARS-CoV-2	1774:1783	arg1	distinct					1789:1796	distinct	1789:1796	distinct	1789:1796	IMPORTANCE Although SARS-CoV-2 is basically regarded as a homolog of SARS-CoV, with their genomic structure and the majority of their genes being highly homologous, the ORF8 genes of SARS-CoV and SARS-CoV-2 are distinct.					
36877072	13	78	theme	SARS-CoV-2	1803:1812	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	78	theme	SARS-CoV-2	1803:1812	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	79	theme	virulence	1928:1936	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	79	theme	virulence	1928:1936	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	2	80	theme	ORF8	333:336	arg1	homologous					360:369	homologous	360:369	homologous	360:369	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	2	80	theme	ORF8	333:336	arg1	protein					338:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein	312:344	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	1	81	theme	responsible	236:246	arg1	pathogen					227:234	the viral pathogen	217:234	the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic	217:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	1	81	theme	responsible	236:246	arg1	coronavirus					187:197	Severe acute respiratory syndrome coronavirus 2	153:199	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	153:212	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	6	82	theme	immunoglobulin-like	718:736	arg1	fold					738:741	an immunoglobulin-like fold	715:741	an immunoglobulin-like fold in a glycan-independent manner	715:772	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36877072	0	83	theme	ORF8	11:14	arg1	Protein					16:22	SARS-CoV-2 ORF8 Protein	0:22	SARS-CoV-2 ORF8 Protein	0:22	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	8	84	theme	intensive	1123:1131	arg1	HSPA5					1133:1137	intensive HSPA5	1123:1137	intensive HSPA5	1123:1137	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	4	85	theme	Oligomannose-type	572:588	arg1	glycosylation					590:602	Oligomannose-type glycosylation	572:602	Oligomannose-type glycosylation	572:602	Oligomannose-type glycosylation has been identified at the N78 site.					
36877072	15	86	theme	virulence	2382:2390	arg1	discrepancy					2392:2402	the superficially known in vivo virulence discrepancy	2350:2402	the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients	2350:2447	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	7	87	theme	substrate-binding	950:966	arg1	domain					968:973	the core substrate-binding domain	941:973	the core substrate-binding domain	941:973	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	15	88	theme	ORF8	2103:2106	arg1	protein					2108:2114	the SARS-CoV-2 ORF8 protein	2088:2114	the SARS-CoV-2 ORF8 protein	2088:2114	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	89	dep	generated	2156:2164	arg1	reticulum					2202:2210	endoplasmic reticulum	2190:2210	endoplasmic reticulum	2190:2210	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	90	theme	SARS-CoV-2	2092:2101	arg1	protein					2108:2114	the SARS-CoV-2 ORF8 protein	2088:2114	the SARS-CoV-2 ORF8 protein	2088:2114	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	13	91	with	homology	1845:1852	arg1	viral					1865:1869	viral	1865:1869	viral	1865:1869	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	91	with	homology	1845:1852	arg1	proteins					1879:1886	host proteins	1874:1886	host proteins	1874:1886	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	92	theme	novel	1914:1918	arg1	gene					1938:1941	a novel special virulence gene	1912:1941	a novel special virulence gene of SARS-CoV-2	1912:1955	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	13	92	theme	novel	1914:1918	arg1	protein					1819:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein	1799:1825	The SARS-CoV-2 ORF8 protein also shows little homology with other viral or host proteins and is thus regarded as a novel special virulence gene of SARS-CoV-2.					
36877072	2	93	theme	other	424:428	arg1	coronaviruses					430:442	other coronaviruses	424:442	other coronaviruses	424:442	The novel SARS-CoV-2 ORF8 protein is not highly homologous with known proteins, including accessory proteins of other coronaviruses.					
36877072	0	94	theme	Reticulum	44:52	arg1	Responses					66:74	Endoplasmic Reticulum Stress-like Responses	32:74	Endoplasmic Reticulum Stress-like Responses	32:74	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	1	95	theme	pandemic	302:309	arg1	disease					278:284	the worldwide coronavirus disease	252:284	the worldwide coronavirus disease 2019 (COVID-19) pandemic	252:309	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic.					
36877072	15	96	theme	stress-like	2212:2222	arg1	responses					2224:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	6	97	theme	endogenous	794:803	arg1	ORF8					805:808	both exogenous and endogenous ORF8	775:808	both exogenous and endogenous ORF8	775:808	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36877072	3	98	theme	signal	475:480	arg1	peptide					482:488	a 15-amino-acid signal peptide	459:488	a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum	459:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	15	99	theme	endoplasmic	2190:2200	arg1	reticulum					2202:2210	endoplasmic reticulum	2190:2210	endoplasmic reticulum	2190:2210	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	15	100	theme	molecular	2059:2067	arg1	characteristics					2069:2083	the unbiased molecular characteristics	2046:2083	the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein	2046:2114	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	6	101	theme	exogenous	780:788	arg1	ORF8					805:808	both exogenous and endogenous ORF8	775:808	both exogenous and endogenous ORF8	775:808	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36877072	0	102	dep	Induces	24:30	arg1	Study					146:150	an Unbiased Study	134:150	an Unbiased Study	134:150	SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.					
36877072	3	103	theme	N	497:497	arg1	terminus					499:506	the N terminus	493:506	the N terminus that localizes the mature protein to the endoplasmic reticulum	493:569	ORF8 contains a 15-amino-acid signal peptide in the N terminus that localizes the mature protein to the endoplasmic reticulum.					
36877072	7	104	theme	globular	921:928	arg1	domain					930:935	the globular domain	917:935	the globular domain	917:935	The key ORF8-binding sites of Calnexin and HSPA5 are indicated on the globular domain and the core substrate-binding domain, respectively.					
36877072	11	105	theme	SARS-CoV-2	1484:1493	arg1	gene					1476:1479	a key unique virulence gene	1453:1479	a key unique virulence gene of SARS-CoV-2	1453:1493	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	11	105	theme	SARS-CoV-2	1484:1493	arg1	ORF8					1438:1441	ORF8	1438:1441	ORF8	1438:1441	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	8	106	theme	stress-responding	1187:1203	arg1	effectors					1205:1213	other stress-responding effectors	1181:1213	other stress-responding effectors	1181:1213	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	106	theme	stress-responding	1187:1203	arg1	CHOP					1226:1229	CHOP	1226:1229	CHOP	1226:1229	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	106	theme	stress-responding	1187:1203	arg1	DERL3					1241:1245	DERL3	1241:1245	DERL3	1241:1245	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	8	106	theme	stress-responding	1187:1203	arg1	EDEM					1232:1235	EDEM	1232:1235	EDEM	1232:1235	ORF8 induces species-dependent endoplasmic reticulum stress-like responses in human cells exclusively via the IRE1 branch, including intensive HSPA5 and PDIA4 upregulation, with increases in other stress-responding effectors, including CHOP, EDEM and DERL3.					
36877072	15	107	theme	generated	2156:2164	arg1	responses					2224:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	rapidly generated but highly controllable endoplasmic reticulum stress-like responses	2148:2232	Our results reveal the unbiased molecular characteristics of the SARS-CoV-2 ORF8 protein and demonstrate that it induces rapidly generated but highly controllable endoplasmic reticulum stress-like responses and facilitates virus replication by triggering Calnexin in human but not mouse cells, providing an explanation for the superficially known in vivo virulence discrepancy of ORF8 between SARS-CoV-2-infected patients and mouse.					
36877072	11	108	theme	key	1455:1457	arg1	gene					1476:1479	a key unique virulence gene	1453:1479	a key unique virulence gene of SARS-CoV-2	1453:1493	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	11	108	theme	key	1455:1457	arg1	ORF8					1438:1441	ORF8	1438:1441	ORF8	1438:1441	Thus, ORF8 serves as a key unique virulence gene of SARS-CoV-2, potentially contributing to COVID-19-specific and/or human-specific pathogenesis.					
36877072	6	109	theme	glycan-independent	748:765	arg1	manner					767:772	a glycan-independent manner	746:772	a glycan-independent manner	746:772	Via an immunoglobulin-like fold in a glycan-independent manner, both exogenous and endogenous ORF8 interacts with human calnexin and HSPA5.					
36383320	0	0	theme	magnetic	85:92	arg1	composite					94:102	a green magnetic composite	77:102	a green magnetic composite	77:102	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	1	1	theme	naphthalene	312:322	arg1	adsorption					298:307	the adsorption	294:307	the adsorption of naphthalene from effluents	294:337	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	0	2	theme	aromatic	37:44	arg1	hydrocarbon					46:56	naphthalene polycyclic aromatic hydrocarbon	14:56	naphthalene polycyclic aromatic hydrocarbon from wastewater	14:72	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	1	3	theme	magnetic	150:157	arg1	mCS/GO					169:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	3	4	theme	initial	662:668	arg1	significant					720:730	significant	720:730	significant	720:730	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	3	4	theme	initial	662:668	arg1	concentration					670:682	the initial concentration	658:682	the initial concentration of NAP	658:689	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	8	5	theme	fifth	1567:1571	arg1	cycle					1573:1577	the fifth cycle	1563:1577	the fifth cycle	1563:1577	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	0	6	theme	green	79:83	arg1	composite					94:102	a green magnetic composite	77:102	a green magnetic composite	77:102	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	3	7	theme	CCD	627:629	arg1	experiment					632:641	a central composite design (CCD) experiment	599:641	a central composite design (CCD) experiment	599:641	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	9	8	theme	green	1584:1588	arg1	composite					1590:1598	The green composite	1580:1598	The green composite	1580:1598	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	9	9	theme	river	1647:1651	arg1	samples					1659:1665	river water samples	1647:1665	river water samples	1647:1665	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	1	10	theme	composite	159:167	arg1	mCS/GO					169:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	4	11	theme	π-π	821:823	arg1	interactions					841:852	π-π and hydrophobic interactions	821:852	π-π and hydrophobic interactions	821:852	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	2	12	theme	crystallographic	485:500	arg1	properties					528:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	0	13	from	Adsorption	0:9	arg1	wastewater					63:72	wastewater	63:72	wastewater	63:72	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	4	14	theme	hydrophobic	829:839	arg1	interactions					841:852	π-π and hydrophobic interactions	821:852	π-π and hydrophobic interactions	821:852	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	6	15	theme	responsible	1153:1163	arg1	physisorption					1122:1134	physisorption	1122:1134	physisorption	1122:1134	The thermodynamic study indicated physisorption as the mechanism responsible for the NAP adsorption.					
36383320	6	15	theme	responsible	1153:1163	arg1	mechanism					1143:1151	the mechanism	1139:1151	the mechanism responsible for the NAP adsorption	1139:1186	The thermodynamic study indicated physisorption as the mechanism responsible for the NAP adsorption.					
36383320	11	16	theme	adsorption	1918:1927	arg1	process					1929:1935	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	0	17	from	wastewater	63:72	arg1	hydrocarbon					46:56	naphthalene polycyclic aromatic hydrocarbon	14:56	naphthalene polycyclic aromatic hydrocarbon from wastewater	14:72	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	0	17	from	wastewater	63:72	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite	0:102	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	2	18	dep	structural	453:462	arg1	XPS					470:472	XPS	470:472	XPS	470:472	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	2	18	dep	structural	453:462	arg1	BET					465:467	BET	465:467	BET	465:467	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	2	18	dep	structural	453:462	arg1	FTIR					478:481	FTIR	478:481	FTIR	478:481	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	8	19	theme	maximum	1297:1303	arg1	capacity					1316:1323	The maximum adsorption capacity	1293:1323	The maximum adsorption capacity (qmax) of the green mCS/GO	1293:1350	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	19	theme	maximum	1297:1303	arg1	334.37 mg g-1					1356:1368	334.37 mg g-1	1356:1368	334.37 mg g-1	1356:1368	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	19	theme	maximum	1297:1303	arg1	qmax					1326:1329	qmax	1326:1329	qmax	1326:1329	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	5	20	dep	kinetic	986:992	arg1	studies					1010:1016	studies	1010:1016	studies	1010:1016	However, the adjustment to the PSO and Freundlich models, obtained through kinetic and equilibrium studies, indicated that chemisorption also influences the adsorptive process.					
36383320	8	21	theme	consecutive	1472:1482	arg1	cycles					1484:1489	five consecutive cycles	1467:1489	five consecutive cycles	1467:1489	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	2	22	dep	thermal	435:441	arg1	TG/DTG					444:449	TG/DTG	444:449	TG/DTG	444:449	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	11	23	theme	aromatic	1890:1897	arg1	PAHs					1912:1915	PAHs	1912:1915	PAHs	1912:1915	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	11	23	theme	aromatic	1890:1897	arg1	hydrocarbon					1899:1909	polycyclic aromatic hydrocarbon	1879:1909	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	9	24	theme	real	1720:1723	arg1	applications					1725:1736	real applications	1720:1736	real applications	1720:1736	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	2	25	theme	different	380:388	arg1	techniques					407:416	different characterization techniques	380:416	different characterization techniques	380:416	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	9	26	theme	method	1710:1715	arg1	feasibility					1691:1701	the feasibility	1687:1701	the feasibility of the method in real applications	1687:1736	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	8	27	dep	75	1553:1554	arg1	to					1550:1551	to	1550:1551	to	1550:1551	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	5	28	theme	adjustment	924:933	arg1	models					961:966	the adjustment to the PSO and Freundlich models	920:966	the adjustment to the PSO and Freundlich models	920:966	However, the adjustment to the PSO and Freundlich models, obtained through kinetic and equilibrium studies, indicated that chemisorption also influences the adsorptive process.					
36383320	8	29	theme	NAP	1510:1512	arg1	recovery					1514:1521	NAP recovery	1510:1521	NAP recovery	1510:1521	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	11	30	theme	polycyclic	1879:1888	arg1	PAHs					1912:1915	PAHs	1912:1915	PAHs	1912:1915	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	11	30	theme	polycyclic	1879:1888	arg1	hydrocarbon					1899:1909	polycyclic aromatic hydrocarbon	1879:1909	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	11	31	theme	first	1822:1826	arg1	it					1812:1813	it	1812:1813	it	1812:1813	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	11	31	theme	first	1822:1826	arg1	time					1828:1831	the first time	1818:1831	the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1818:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	9	32	theme	water	1653:1657	arg1	samples					1659:1665	river water samples	1647:1665	river water samples	1647:1665	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	9	33	theme	NAP	1638:1640	arg1	adsorption					1624:1633	the adsorption	1620:1633	the adsorption of NAP from river water samples	1620:1665	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	0	34	theme	polycyclic	26:35	arg1	hydrocarbon					46:56	naphthalene polycyclic aromatic hydrocarbon	14:56	naphthalene polycyclic aromatic hydrocarbon from wastewater	14:72	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	11	35	dep	time	1828:1831	arg1	recycled					1860:1867	recycled	1860:1867	was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1856:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	0	36	theme	graphene	126:133	arg1	oxide					135:139	graphene oxide	126:139	graphene oxide	126:139	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	1	37	theme	water	198:202	arg1	agent					283:287	a crosslinking agent	268:287	a crosslinking agent	268:287	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	1	37	theme	water	198:202	arg1	agent					236:240	a reducing agent	225:240	a reducing agent	225:240	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	1	37	theme	water	198:202	arg1	extract					213:219	water hyacinth extract	198:219	water hyacinth extract	198:219	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	0	38	theme	naphthalene	14:24	arg1	hydrocarbon					46:56	naphthalene polycyclic aromatic hydrocarbon	14:56	naphthalene polycyclic aromatic hydrocarbon from wastewater	14:72	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	1	39	theme	crosslinking	270:281	arg1	agent					283:287	a crosslinking agent	268:287	a crosslinking agent	268:287	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	1	39	theme	crosslinking	270:281	arg1	extract					213:219	water hyacinth extract	198:219	water hyacinth extract	198:219	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	4	40	theme	main	864:867	arg1	physisorption					798:810	physisorption	798:810	physisorption	798:810	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	4	40	theme	main	864:867	arg1	mechanism					869:877	the main mechanism	860:877	the main mechanism involved in the NAP adsorption	860:908	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	8	41	theme	green	1397:1401	arg1	mCS/GO					1403:1408	the green mCS/GO	1393:1408	the green mCS/GO	1393:1408	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	6	42	theme	thermodynamic	1092:1104	arg1	study					1106:1110	The thermodynamic study	1088:1110	The thermodynamic study	1088:1110	The thermodynamic study indicated physisorption as the mechanism responsible for the NAP adsorption.					
36383320	8	43	theme	recovery	1514:1521	arg1	percentage					1496:1505	the percentage	1492:1505	the percentage of NAP recovery	1492:1521	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	0	44	theme	hydrocarbon	46:56	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite	0:102	Adsorption of naphthalene polycyclic aromatic hydrocarbon from wastewater by a green magnetic composite based on chitosan and graphene oxide.					
36383320	3	45	theme	NAP	687:689	arg1	dosage					709:714	the adsorbent dosage	695:714	the adsorbent dosage	695:714	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	3	45	theme	NAP	687:689	arg1	significant					720:730	significant	720:730	significant	720:730	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	3	45	theme	NAP	687:689	arg1	concentration					670:682	the initial concentration	658:682	the initial concentration of NAP	658:689	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	2	46	dep	crystallographic	485:500	arg1	XRD					503:505	XRD	503:505	XRD	503:505	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	8	47	theme	mCS/GO	1345:1350	arg1	capacity					1316:1323	The maximum adsorption capacity	1293:1323	The maximum adsorption capacity (qmax) of the green mCS/GO	1293:1350	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	47	theme	mCS/GO	1345:1350	arg1	334.37 mg g-1					1356:1368	334.37 mg g-1	1356:1368	334.37 mg g-1	1356:1368	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	47	theme	mCS/GO	1345:1350	arg1	qmax					1326:1329	qmax	1326:1329	qmax	1326:1329	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	48	from	20 °C.	1373:1378	arg1	capacity					1316:1323	The maximum adsorption capacity	1293:1323	The maximum adsorption capacity (qmax) of the green mCS/GO	1293:1350	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	48	from	20 °C.	1373:1378	arg1	334.37 mg g-1					1356:1368	334.37 mg g-1	1356:1368	334.37 mg g-1	1356:1368	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	1	49	from	effluents	329:337	arg1	adsorption					298:307	the adsorption	294:307	the adsorption of naphthalene from effluents	294:337	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	2	50	theme	structural	453:462	arg1	properties					528:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	9	51	from	feasibility	1691:1701	arg1	applications					1725:1736	real applications	1720:1736	real applications	1720:1736	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	2	52	theme	thermal	435:441	arg1	properties					528:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	2	53	theme	characterization	390:405	arg1	techniques					407:416	different characterization techniques	380:416	different characterization techniques	380:416	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	4	54	theme	NAP	895:897	arg1	adsorption					899:908	the NAP adsorption	891:908	the NAP adsorption	891:908	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	8	55	theme	adsorption	1305:1314	arg1	capacity					1316:1323	The maximum adsorption capacity	1293:1323	The maximum adsorption capacity (qmax) of the green mCS/GO	1293:1350	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	55	theme	adsorption	1305:1314	arg1	334.37 mg g-1					1356:1368	334.37 mg g-1	1356:1368	334.37 mg g-1	1356:1368	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	8	55	theme	adsorption	1305:1314	arg1	qmax					1326:1329	qmax	1326:1329	qmax	1326:1329	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	3	56	theme	adsorbent	699:707	arg1	dosage					709:714	the adsorbent dosage	695:714	the adsorbent dosage	695:714	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	3	56	theme	adsorbent	699:707	arg1	significant					720:730	significant	720:730	significant	720:730	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	7	57	contain	has	1209:1211	arg1	adsorbent					1199:1207	adsorbent	1199:1207	adsorbent	1199:1207	Also, the adsorbent has high affinity for the adsorbate and the process is spontaneous and endothermic.					
36383320	7	57	contain	has	1209:1211	arg2	affinity					1218:1225	high affinity	1213:1225	high affinity for the adsorbate	1213:1243	Also, the adsorbent has high affinity for the adsorbate and the process is spontaneous and endothermic.					
36383320	3	58	theme	design	619:624	arg1	experiment					632:641	a central composite design (CCD) experiment	599:641	a central composite design (CCD) experiment	599:641	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	4	59	theme	adsorption	765:774	arg1	assays					776:781	The adsorption assays	761:781	The adsorption assays	761:781	The adsorption assays indicated that physisorption, through π-π and hydrophobic interactions, were the main mechanism involved in the NAP adsorption.					
36383320	9	60	from	samples	1659:1665	arg1	adsorption					1624:1633	the adsorption	1620:1633	the adsorption of NAP from river water samples	1620:1665	The green composite was also applied in the adsorption of NAP from river water samples, aiming to evaluate the feasibility of the method in real applications.					
36383320	2	61	theme	textural	513:520	arg1	properties					528:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties	431:537	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	8	62	theme	green	1339:1343	arg1	mCS/GO					1345:1350	the green mCS/GO	1335:1350	the green mCS/GO	1335:1350	The maximum adsorption capacity (qmax) of the green mCS/GO was 334.37 mg g-1 at 20 °C. Furthermore, the green mCS/GO was effectively regenerated with methanol and reused for five consecutive cycles, the percentage of NAP recovery went from approximately 91 to 75% after the fifth cycle.					
36383320	3	63	theme	adsorption	740:749	arg1	capacity					751:758	the adsorption capacity	736:758	the adsorption capacity	736:758	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	11	64	theme	hydrocarbon	1899:1909	arg1	process					1929:1935	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	the polycyclic aromatic hydrocarbon (PAHs) adsorption process	1875:1935	From what we know, this it is the first time that a green adsorbent was recycled after the polycyclic aromatic hydrocarbon (PAHs) adsorption process.					
36383320	3	65	theme	central	601:607	arg1	experiment					632:641	a central composite design (CCD) experiment	599:641	a central composite design (CCD) experiment	599:641	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	6	66	theme	NAP	1173:1175	arg1	adsorption					1177:1186	the NAP adsorption	1169:1186	the NAP adsorption	1169:1186	The thermodynamic study indicated physisorption as the mechanism responsible for the NAP adsorption.					
36383320	2	67	theme	green	344:348	arg1	composite					350:358	The green composite	340:358	The green composite	340:358	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	2	68	dep	textural	513:520	arg1	SEM					523:525	SEM	523:525	SEM	523:525	The green composite was evaluated using different characterization techniques to determine its thermal (TG/DTG), structural (BET, XPS and FTIR), crystallographic (XRD), and textural (SEM) properties in natura and post-adsorption.					
36383320	3	69	theme	composite	609:617	arg1	experiment					632:641	a central composite design (CCD) experiment	599:641	a central composite design (CCD) experiment	599:641	The results obtained through a central composite design (CCD) experiment indicated that the initial concentration of NAP and the adsorbent dosage are significant for the adsorption capacity.					
36383320	10	70	theme	adsorption	1743:1752	arg1	%					1785:1785	approximately 70%	1769:1785	approximately 70%	1769:1785	The adsorption efficiency was approximately 70%.					
36383320	10	70	theme	adsorption	1743:1752	arg1	efficiency					1754:1763	The adsorption efficiency	1739:1763	The adsorption efficiency	1739:1763	The adsorption efficiency was approximately 70%.					
36383320	5	71	dep	PSO	942:944	arg1	the					938:940	the	938:940	the	938:940	However, the adjustment to the PSO and Freundlich models, obtained through kinetic and equilibrium studies, indicated that chemisorption also influences the adsorptive process.					
36383320	7	72	theme	high	1213:1216	arg1	affinity					1218:1225	high affinity	1213:1225	high affinity for the adsorbate	1213:1243	Also, the adsorbent has high affinity for the adsorbate and the process is spontaneous and endothermic.					
36383320	1	73	theme	reducing	227:234	arg1	agent					236:240	a reducing agent	225:240	a reducing agent	225:240	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	1	73	theme	reducing	227:234	arg1	extract					213:219	water hyacinth extract	198:219	water hyacinth extract	198:219	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36383320	5	74	theme	adsorptive	1068:1077	arg1	process					1079:1085	the adsorptive process	1064:1085	the adsorptive process	1064:1085	However, the adjustment to the PSO and Freundlich models, obtained through kinetic and equilibrium studies, indicated that chemisorption also influences the adsorptive process.					
36383320	1	75	theme	green	144:148	arg1	mCS/GO					169:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO	142:174	A green magnetic composite mCS/GO was synthesized using water hyacinth extract, as a reducing agent, and proanthocyanidin, as a crosslinking agent, for the adsorption of naphthalene from effluents.					
36135751	4	0	theme	oxygen	949:954	arg1	species					956:962	reactive oxygen species	940:962	reactive oxygen species scavenging	940:973	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	7	1	theme	Antarctic	1558:1566	arg1	extracts					1581:1588	the Antarctic marine algae extracts	1554:1588	the Antarctic marine algae extracts	1554:1588	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	8	2	theme	marine	1804:1809	arg1	algae					1811:1815	Antarctic marine algae	1794:1815	Antarctic marine algae	1794:1815	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	8	3	theme	barrier	2043:2049	arg1	function					2051:2058	the protective barrier function	2028:2058	the protective barrier function of the intestine and skin	2028:2084	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	6	4	from	compounds	1372:1380	arg1	extracts					1390:1397	the extracts	1386:1397	the extracts	1386:1397	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	7	5	theme	cell	1600:1603	arg1	viability					1605:1613	cell viability	1600:1613	cell viability	1600:1613	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	4	6	theme	cell	921:924	arg1	viability					926:934	cell viability	921:934	cell viability	921:934	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	7	theme	intestine	2067:2075	arg1	function					2051:2058	the protective barrier function	2028:2058	the protective barrier function of the intestine and skin	2028:2084	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	6	8	theme	antioxidant	1436:1446	arg1	activities					1448:1457	antioxidant activities	1436:1457	antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals	1436:1538	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	5	9	theme	extracts	1142:1149	arg1	activities					1124:1133	the barrier-protective activities	1101:1133	the barrier-protective activities of the extracts	1101:1149	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	4	10	from	properties	485:494	arg1	cells					532:536	epithelial cells	521:536	epithelial cells	521:536	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	5	11	theme	intestinal	1154:1163	arg1	lines					1187:1191	intestinal and keratinocyte cell lines	1154:1191	lines	1187:1191	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	2	12	theme	organs	244:249	arg1	function					226:233	the epithelial barrier function	203:233	the epithelial barrier function of these organs	203:249	Strengthening the epithelial barrier function of these organs is critical for maintaining homeostasis against inflammatory stimuli.					
36135751	8	13	theme	compounds	1924:1932	arg1	properties					1910:1919	the bioactive properties	1896:1919	the bioactive properties of compounds produced by Antarctic marine algae	1896:1967	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	4	14	theme	polar	499:503	arg1	algae					512:516	polar marine algae	499:516	polar marine algae on epithelial cells of the intestine and skin	499:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	6	15	theme	several	1342:1348	arg1	acids					1356:1360	several fatty acids	1342:1360	several fatty acids	1342:1360	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	5	16	theme	barrier-protective	1105:1122	arg1	activities					1124:1133	the barrier-protective activities	1101:1133	the barrier-protective activities of the extracts	1101:1149	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	3	17	theme	Recent	321:326	arg1	studies					328:334	Recent studies	321:334	Recent studies	321:334	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	8	18	theme	skin	2081:2084	arg1	function					2051:2058	the protective barrier function	2028:2058	the protective barrier function of the intestine and skin	2028:2084	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	4	19	theme	chromatography-mass	773:791	arg1	spectrometry					793:804	gas chromatography-mass spectrometry	769:804	gas chromatography-mass spectrometry	769:804	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	20	theme	marine	1956:1961	arg1	algae					1963:1967	Antarctic marine algae	1946:1967	Antarctic marine algae	1946:1967	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	7	21	theme	ultraviolet	1744:1754	arg1	radiation					1756:1764	ultraviolet radiation	1744:1764	ultraviolet radiation	1744:1764	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	6	22	theme	bioactive	1311:1319	arg1	compounds					1321:1329	bioactive compounds	1311:1329	bioactive compounds	1311:1329	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	6	22	theme	bioactive	1311:1319	arg1	acids					1356:1360	several fatty acids	1342:1360	several fatty acids	1342:1360	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	3	23	theme	polar	349:353	arg1	algae					362:366	polar marine algae	349:366	polar marine algae	349:366	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	3	23	theme	polar	349:353	arg1	resource					394:401	a promising bioactive resource	372:401	a promising bioactive resource	372:401	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	6	24	theme	oxygen	1494:1499	arg1	species					1501:1507	intracellular reactive oxygen species	1471:1507	intracellular reactive oxygen species	1471:1507	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	5	25	theme	electrical	1222:1231	arg1	resistance					1233:1242	transepithelial electrical resistance	1206:1242	transepithelial electrical resistance	1206:1242	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	3	26	theme	bioactive	384:392	arg1	algae					362:366	polar marine algae	349:366	polar marine algae	349:366	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	3	26	theme	bioactive	384:392	arg1	resource					394:401	a promising bioactive resource	372:401	a promising bioactive resource	372:401	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	4	27	theme	intestine	545:553	arg1	algae					512:516	polar marine algae	499:516	polar marine algae on epithelial cells of the intestine and skin	499:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	28	theme	protective	822:831	arg1	activities					833:842	the protective activities	818:842	the protective activities of the extracts on human intestinal and keratinocyte cell lines	818:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	6	29	from	compounds	1321:1329	arg1	extracts					1390:1397	the extracts	1386:1397	the extracts	1386:1397	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	0	30	theme	Barrier	86:92	arg1	Integrity					94:102	Epithelial Barrier Integrity	75:102	Epithelial Barrier Integrity	75:102	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	5	31	theme	keratinocyte	1169:1180	arg1	lines					1187:1191	intestinal and keratinocyte cell lines	1154:1191	lines	1187:1191	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	4	32	theme	algae	512:516	arg1	properties					485:494	the bioactive properties	471:494	the bioactive properties of polar marine algae on epithelial cells of the intestine and skin	471:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	33	theme	Antarctic	1794:1802	arg1	algae					1811:1815	Antarctic marine algae	1794:1815	Antarctic marine algae	1794:1815	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	5	34	theme	real-time	1047:1055	arg1	reaction					1074:1081	real-time polymerase chain reaction	1047:1081	real-time polymerase chain reaction	1047:1081	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	4	35	theme	epithelial	521:530	arg1	cells					532:536	epithelial cells	521:536	epithelial cells	521:536	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	0	36	theme	Antarctic	0:8	arg1	Algae					17:21	Antarctic Marine Algae	0:21	Antarctic Marine Algae Extracts as a Potential Natural Resource	0:62	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	0	37	theme	Algae	17:21	arg1	Extracts					23:30	Antarctic Marine Algae Extracts	0:30	Antarctic Marine Algae Extracts as a Potential Natural Resource	0:62	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	4	38	theme	skin	559:562	arg1	algae					512:516	polar marine algae	499:516	polar marine algae on epithelial cells of the intestine and skin	499:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	39	theme	cell	897:900	arg1	lines					902:906	human intestinal and keratinocyte cell lines	863:906	human intestinal and keratinocyte cell lines	863:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	0	40	theme	Potential	37:45	arg1	Resource					55:62	a Potential Natural Resource	35:62	a Potential Natural Resource	35:62	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	5	41	theme	dextran	1269:1275	arg1	flux					1277:1280	fluorescence-labeled dextran flux	1248:1280	fluorescence-labeled dextran flux	1248:1280	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	2	42	theme	barrier	218:224	arg1	function					226:233	the epithelial barrier function	203:233	the epithelial barrier function of these organs	203:249	Strengthening the epithelial barrier function of these organs is critical for maintaining homeostasis against inflammatory stimuli.					
36135751	4	43	theme	extracts	851:858	arg1	activities					833:842	the protective activities	818:842	the protective activities of the extracts on human intestinal and keratinocyte cell lines	818:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	5	44	theme	chain	1068:1072	arg1	reaction					1074:1081	real-time polymerase chain reaction	1047:1081	real-time polymerase chain reaction	1047:1081	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	4	45	theme	human	863:867	arg1	lines					902:906	human intestinal and keratinocyte cell lines	863:906	human intestinal and keratinocyte cell lines	863:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	46	dep	intestine	545:553	arg1	the					541:543	the	541:543	the	541:543	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	47	theme	protective	2032:2041	arg1	function					2051:2058	the protective barrier function	2028:2058	the protective barrier function of the intestine and skin	2028:2084	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	8	48	theme	polar	1854:1858	arg1	environments					1860:1871	polar environments	1854:1871	polar environments	1854:1871	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	4	49	theme	reactive	940:947	arg1	species					956:962	reactive oxygen species	940:962	reactive oxygen species scavenging	940:973	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	7	50	theme	marine	1568:1573	arg1	extracts					1581:1588	the Antarctic marine algae extracts	1554:1588	the Antarctic marine algae extracts	1554:1588	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	4	51	theme	grandifolius	628:639	arg1	extracts					576:583	extracts	576:583	extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica	576:713	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	52	from	cells	532:536	arg1	properties					485:494	the bioactive properties	471:494	the bioactive properties of polar marine algae on epithelial cells of the intestine and skin	471:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	2	53	theme	inflammatory	299:310	arg1	stimuli					312:318	inflammatory stimuli	299:318	inflammatory stimuli	299:318	Strengthening the epithelial barrier function of these organs is critical for maintaining homeostasis against inflammatory stimuli.					
36135751	1	54	theme	external	167:174	arg1	environment					176:186	the external environment	163:186	the external environment	163:186	The intestine and skin provide crucial protection against the external environment.					
36135751	6	55	theme	specific	1522:1529	arg1	radicals					1531:1538	specific radicals	1522:1538	specific radicals	1522:1538	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	7	56	theme	algae	1575:1579	arg1	extracts					1581:1588	the Antarctic marine algae extracts	1554:1588	the Antarctic marine algae extracts	1554:1588	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	4	57	theme	antarctica	704:713	arg1	extracts					576:583	extracts	576:583	extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica	576:713	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	6	58	theme	lipid	1366:1370	arg1	compounds					1372:1380	lipid compounds	1366:1380	lipid compounds	1366:1380	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	6	58	theme	lipid	1366:1370	arg1	acids					1356:1360	several fatty acids	1342:1360	several fatty acids	1342:1360	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	4	59	from	algae	512:516	arg1	cells					532:536	epithelial cells	521:536	epithelial cells	521:536	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	60	theme	antarcticus	676:686	arg1	extracts					576:583	extracts	576:583	extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica	576:713	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	61	theme	bioactive	1900:1908	arg1	properties					1910:1919	the bioactive properties	1896:1919	the bioactive properties of compounds produced by Antarctic marine algae	1896:1967	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	4	62	theme	marine	505:510	arg1	algae					512:516	polar marine algae	499:516	polar marine algae on epithelial cells of the intestine and skin	499:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	6	63	theme	fatty	1350:1354	arg1	acids					1356:1360	several fatty acids	1342:1360	several fatty acids	1342:1360	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	4	64	theme	species	956:962	arg1	scavenging					964:973	reactive oxygen species scavenging	940:973	reactive oxygen species scavenging	940:973	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	65	theme	extracts	754:761	arg1	profiles					738:745	the compound profiles	725:745	the compound profiles of the extracts using gas chromatography-mass spectrometry	725:804	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	66	theme	bioactive	475:483	arg1	properties					485:494	the bioactive properties	471:494	the bioactive properties of polar marine algae on epithelial cells of the intestine and skin	471:562	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	4	67	theme	gas	769:771	arg1	spectrometry					793:804	gas chromatography-mass spectrometry	769:804	gas chromatography-mass spectrometry	769:804	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	68	theme	Antarctic	1946:1954	arg1	algae					1963:1967	Antarctic marine algae	1946:1967	Antarctic marine algae	1946:1967	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	1	69	theme	crucial	136:142	arg1	protection					144:153	crucial protection	136:153	crucial protection against the external environment	136:186	The intestine and skin provide crucial protection against the external environment.					
36135751	8	70	dep	intestine	2067:2075	arg1	the					2063:2065	the	2063:2065	the	2063:2065	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	4	71	theme	compound	729:736	arg1	profiles					738:745	the compound profiles	725:745	the compound profiles of the extracts using gas chromatography-mass spectrometry	725:804	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	6	72	theme	intracellular	1471:1483	arg1	species					1501:1507	intracellular reactive oxygen species	1471:1507	intracellular reactive oxygen species	1471:1507	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	0	73	theme	Epithelial	75:84	arg1	Integrity					94:102	Epithelial Barrier Integrity	75:102	Epithelial Barrier Integrity	75:102	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	5	74	theme	transepithelial	1206:1220	arg1	resistance					1233:1242	transepithelial electrical resistance	1206:1242	transepithelial electrical resistance	1206:1242	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	7	75	theme	cells	1705:1709	arg1	integrity					1692:1700	the barrier integrity	1680:1700	the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation	1680:1764	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	3	76	theme	marine	355:360	arg1	algae					362:366	polar marine algae	349:366	polar marine algae	349:366	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	3	76	theme	marine	355:360	arg1	resource					394:401	a promising bioactive resource	372:401	a promising bioactive resource	372:401	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	6	77	theme	reactive	1485:1492	arg1	species					1501:1507	intracellular reactive oxygen species	1471:1507	intracellular reactive oxygen species	1471:1507	We identified bioactive compounds, including several fatty acids and lipid compounds, in the extracts, and found that the extracts perform antioxidant activities that remove intracellular reactive oxygen species and scavenge specific radicals.					
36135751	4	78	from	activities	833:842	arg1	lines					902:906	human intestinal and keratinocyte cell lines	863:906	human intestinal and keratinocyte cell lines	863:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	8	79	used	used	1988:1991	arg2	properties					1910:1919	the bioactive properties	1896:1919	the bioactive properties of compounds produced by Antarctic marine algae	1896:1967	These results suggest that Antarctic marine algae have optimized their composition for polar environments, and furthermore, that the bioactive properties of compounds produced by Antarctic marine algae can potentially be used to develop therapeutics to promote the protective barrier function of the intestine and skin.					
36135751	5	80	theme	cell	1182:1185	arg1	lines					1187:1191	intestinal and keratinocyte cell lines	1154:1191	lines	1187:1191	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	3	81	theme	promising	374:382	arg1	algae					362:366	polar marine algae	349:366	polar marine algae	349:366	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	3	81	theme	promising	374:382	arg1	resource					394:401	a promising bioactive resource	372:401	a promising bioactive resource	372:401	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	0	82	theme	Marine	10:15	arg1	Algae					17:21	Antarctic Marine Algae	0:21	Antarctic Marine Algae Extracts as a Potential Natural Resource	0:62	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	5	83	theme	immune	1001:1006	arg1	responses					1008:1016	immune responses	1001:1016	immune responses modulated by the extracts by real-time polymerase chain reaction	1001:1081	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	7	84	theme	barrier	1684:1690	arg1	integrity					1692:1700	the barrier integrity	1680:1700	the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation	1680:1764	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36135751	4	85	theme	intestinal	869:878	arg1	lines					902:906	human intestinal and keratinocyte cell lines	863:906	human intestinal and keratinocyte cell lines	863:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	0	86	theme	Natural	47:53	arg1	Resource					55:62	a Potential Natural Resource	35:62	a Potential Natural Resource	35:62	Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.					
36135751	5	87	theme	fluorescence-labeled	1248:1267	arg1	flux					1277:1280	fluorescence-labeled dextran flux	1248:1280	fluorescence-labeled dextran flux	1248:1280	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	3	88	theme	extreme	434:440	arg1	environments					442:453	extreme environments	434:453	extreme environments	434:453	Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments.					
36135751	4	89	theme	keratinocyte	884:895	arg1	lines					902:906	human intestinal and keratinocyte cell lines	863:906	human intestinal and keratinocyte cell lines	863:906	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	5	90	theme	polymerase	1057:1066	arg1	reaction					1074:1081	real-time polymerase chain reaction	1047:1081	real-time polymerase chain reaction	1047:1081	In addition, we assessed immune responses modulated by the extracts by real-time polymerase chain reaction, and we monitored the barrier-protective activities of the extracts on intestinal and keratinocyte cell lines by measuring transepithelial electrical resistance and fluorescence-labeled dextran flux, respectively.					
36135751	4	91	theme	cartilagineum	652:664	arg1	extracts					576:583	extracts	576:583	extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica	576:713	To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestinal and keratinocyte cell lines by measuring cell viability and reactive oxygen species scavenging.					
36135751	2	92	theme	epithelial	207:216	arg1	function					226:233	the epithelial barrier function	203:233	the epithelial barrier function of these organs	203:249	Strengthening the epithelial barrier function of these organs is critical for maintaining homeostasis against inflammatory stimuli.					
36135751	7	93	theme	inflammatory	1640:1651	arg1	stimulation					1653:1663	inflammatory stimulation	1640:1663	inflammatory stimulation	1640:1663	Furthermore, the Antarctic marine algae extracts increased cell viability, protected cells against inflammatory stimulation, and increased the barrier integrity of cells damaged by lipopolysaccharide or ultraviolet radiation.					
36876789	0	0	theme	different	79:87	arg1	strategies					102:111	two different pretreatment strategies	75:111	two different pretreatment strategies	75:111	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	1	1	theme	xylan-rich	143:152	arg1	wastes					167:172	abundant xylan-rich agricultural wastes	134:172	abundant xylan-rich agricultural wastes	134:172	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	1	1	theme	xylan-rich	143:152	arg1	cobs					119:122	Corn cobs	114:122	Corn cobs (CCs)	114:128	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	4	2	theme	alkali	569:574	arg1	route					589:593	alkali pretreatment route	569:593	alkali pretreatment route	569:593	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	1	3	theme	agricultural	154:165	arg1	wastes					167:172	abundant xylan-rich agricultural wastes	134:172	abundant xylan-rich agricultural wastes	134:172	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	1	3	theme	agricultural	154:165	arg1	cobs					119:122	Corn cobs	114:122	Corn cobs (CCs)	114:128	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	0	4	theme	strategies	102:111	arg1	Assessment					61:70	Assessment	61:70	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.	0:112	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	2	5	theme	enzymes	328:334	arg1	set					288:290	a set	286:290	a set	286:290	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	5	theme	enzymes	328:334	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	4	6	theme	hydrothermal	702:713	arg1	pretreatment					715:726	hydrothermal pretreatment	702:726	hydrothermal pretreatment using a combination of GH10 and GH11 enzymes	702:771	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	3	7	theme	samples	524:530	arg1	composition					478:488	chemical composition	469:488	chemical composition	469:488	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	3	7	theme	samples	524:530	arg1	structure					503:511	physical structure	494:511	physical structure	494:511	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	2	8	from	set	288:290	arg1	families					355:362	GH10 and GH11 families	341:362	families	355:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	0	9	theme	pretreatment	89:100	arg1	strategies					102:111	two different pretreatment strategies	75:111	two different pretreatment strategies	75:111	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	4	10	theme	pretreatment	576:587	arg1	route					589:593	alkali pretreatment route	569:593	alkali pretreatment route	569:593	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	5	11	theme	sustainable	819:829	arg1	valorization					841:852	ecologically sustainable enzymatic valorization	806:852	ecologically sustainable enzymatic valorization of CCs	806:859	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	0	12	from	cobs	55:58	arg1	production					10:19	Enzymatic production	0:19	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.	0:112	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	5	13	theme	valorization	841:852	arg1	promise					795:801	a promise	793:801	a promise of ecologically sustainable enzymatic valorization of CCs	793:859	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	3	14	theme	CCs	520:522	arg1	samples					524:530	the CCs samples	516:530	the CCs samples	516:530	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	3	15	theme	chemical	469:476	arg1	composition					478:488	chemical composition	469:488	chemical composition	469:488	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	4	16	theme	biomass	637:643	arg1	gram					621:624	gram	621:624	gram of initial biomass	621:643	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	5	17	theme	CCs	857:859	arg1	valorization					841:852	ecologically sustainable enzymatic valorization	806:852	ecologically sustainable enzymatic valorization of CCs	806:859	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	0	18	theme	Enzymatic	0:8	arg1	production					10:19	Enzymatic production	0:19	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.	0:112	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	2	19	contain	have	371:374	arg2	restrictions					386:397	different restrictions	376:397	different restrictions for xylan substitutions	376:421	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	19	contain	have	371:374	arg1	set					288:290	a set	286:290	a set	286:290	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	19	contain	have	371:374	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	20	theme	GH11	350:353	arg1	families					355:362	GH10 and GH11 families	341:362	families	355:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	0	21	theme	xylooligosaccharides	24:43	arg1	production					10:19	Enzymatic production	0:19	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.	0:112	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	2	22	theme	pretreatment	235:246	arg1	hydrothermal					266:277	hydrothermal	266:277	hydrothermal	266:277	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	22	theme	pretreatment	235:246	arg1	alkali					255:260	alkali	255:260	alkali	255:260	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	22	theme	pretreatment	235:246	arg1	routs					248:252	two different pretreatment routs	221:252	two different pretreatment routs	221:252	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	23	theme	xylan	403:407	arg1	substitutions					409:421	xylan substitutions	403:421	xylan substitutions	403:421	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	1	24	theme	Corn	114:117	arg1	CCs					125:127	CCs	125:127	CCs	125:127	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	1	24	theme	Corn	114:117	arg1	cobs					119:122	Corn cobs	114:122	Corn cobs (CCs)	114:128	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	1	24	theme	Corn	114:117	arg1	wastes					167:172	abundant xylan-rich agricultural wastes	134:172	abundant xylan-rich agricultural wastes	134:172	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	0	25	theme	corn	50:53	arg1	cobs					55:58	corn cobs	50:58	corn cobs	50:58	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	5	26	theme	XOS	889:891	arg1	production					893:902	sustainable XOS production	877:902	sustainable XOS production	877:902	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	4	27	theme	initial	629:635	arg1	biomass					637:643	initial biomass	629:643	initial biomass	629:643	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	2	28	theme	different	376:384	arg1	restrictions					386:397	different restrictions	376:397	different restrictions for xylan substitutions	376:421	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	29	from	families	355:362	arg1	set					288:290	a set	286:290	a set	286:290	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	29	from	families	355:362	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	5	30	theme	enzymatic	831:839	arg1	valorization					841:852	ecologically sustainable enzymatic valorization	806:852	ecologically sustainable enzymatic valorization of CCs	806:859	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	3	31	from	impacts	437:443	arg1	composition					478:488	chemical composition	469:488	chemical composition	469:488	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	3	31	from	impacts	437:443	arg1	structure					503:511	physical structure	494:511	physical structure	494:511	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	2	32	theme	exo-acting	317:326	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	33	theme	GH10	341:344	arg1	families					355:362	GH10 and GH11 families	341:362	families	355:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	34	theme	XOS	197:199	arg1	yields					201:206	CCs XOS yields	193:206	CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal,	193:278	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	3	35	theme	physical	494:501	arg1	structure					503:511	physical structure	494:511	physical structure	494:511	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	4	36	theme	115 mg/g	676:683	arg1	yield					667:671	an overall XOS yield	652:671	an overall XOS yield of 115 mg/g	652:683	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	2	37	theme	CCs	193:195	arg1	yields					201:206	CCs XOS yields	193:206	CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal,	193:278	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	4	38	theme	enzymes	765:771	arg1	combination					736:746	a combination	734:746	a combination of GH10 and GH11 enzymes	734:771	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	4	39	theme	overall	655:661	arg1	yield					667:671	an overall XOS yield	652:671	an overall XOS yield of 115 mg/g	652:683	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	2	40	theme	endo-	307:311	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	4	41	theme	GH10	751:754	arg1	enzymes					765:771	GH10 and GH11 enzymes	751:771	enzymes	765:771	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	5	42	theme	sustainable	877:887	arg1	production					893:902	sustainable XOS production	877:902	sustainable XOS production	877:902	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	4	43	theme	GH11	760:763	arg1	enzymes					765:771	GH10 and GH11 enzymes	751:771	enzymes	765:771	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	2	44	theme	recombinant	295:305	arg1	enzymes					328:334	recombinant endo- and exo-acting enzymes	295:334	recombinant endo- and exo-acting enzymes from GH10 and GH11 families	295:362	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	3	45	theme	pretreatments	452:464	arg1	impacts					437:443	impacts	437:443	impacts of the pretreatments on chemical composition and physical structure of the CCs samples	437:530	Furthermore, impacts of the pretreatments on chemical composition and physical structure of the CCs samples were evaluated.					
36876789	5	46	theme	green	866:870	arg1	"					871:871	"green"	865:871	"green"	865:871	These results hold a promise of ecologically sustainable enzymatic valorization of CCs via "green" and sustainable XOS production.					
36876789	0	47	dep	production	10:19	arg1	Assessment					61:70	Assessment	61:70	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.	0:112	Enzymatic production of xylooligosaccharides from corn cobs: Assessment of two different pretreatment strategies.					
36876789	4	48	theme	XOS	663:665	arg1	yield					667:671	an overall XOS yield	652:671	an overall XOS yield of 115 mg/g	652:683	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	4	49	theme	XOS	613:615	arg1	59 mg					604:608	59 mg	604:608	59 mg of XOS	604:615	We demonstrated that alkali pretreatment route rendered 59 mg of XOS per gram of initial biomass, while an overall XOS yield of 115 mg/g was achieved via hydrothermal pretreatment using a combination of GH10 and GH11 enzymes.					
36876789	2	50	theme	different	225:233	arg1	hydrothermal					266:277	hydrothermal	266:277	hydrothermal	266:277	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	50	theme	different	225:233	arg1	alkali					255:260	alkali	255:260	alkali	255:260	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	2	50	theme	different	225:233	arg1	routs					248:252	two different pretreatment routs	221:252	two different pretreatment routs	221:252	Here, we compared CCs XOS yields obtained via two different pretreatment routs, alkali and hydrothermal, using a set of recombinant endo- and exo-acting enzymes from GH10 and GH11 families, which have different restrictions for xylan substitutions.					
36876789	1	51	theme	abundant	134:141	arg1	wastes					167:172	abundant xylan-rich agricultural wastes	134:172	abundant xylan-rich agricultural wastes	134:172	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
36876789	1	51	theme	abundant	134:141	arg1	cobs					119:122	Corn cobs	114:122	Corn cobs (CCs)	114:128	Corn cobs (CCs) are abundant xylan-rich agricultural wastes.					
35727166	0	0	theme	oxygen	91:96	arg1	species					98:104	reactive oxygen species	82:104	reactive oxygen species	82:104	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase.					
35727166	5	1	theme	HA	741:742	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	8	2	from	weight	1604:1609	arg1	material					1654:1661	the range 500-2000 kDa and cross-linked material	1614:1661	the range 500-2000 kDa and cross-linked material without CS	1614:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	3	theme	cross-linked	1641:1652	arg1	material					1654:1661	the range 500-2000 kDa and cross-linked material	1614:1661	the range 500-2000 kDa and cross-linked material without CS	1614:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	4	4	theme	temporal	552:559	arg1	effect					573:578	only temporal therapeutic effect	547:578	only temporal therapeutic effect	547:578	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
35727166	0	5	theme	reactive	82:89	arg1	species					98:104	reactive oxygen species	82:104	reactive oxygen species	82:104	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase.					
35727166	6	6	theme	range	1042:1046	arg1	devices					1107:1113	medical devices	1099:1113	medical devices	1099:1113	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	6	6	theme	range	1042:1046	arg1	500-2000 kDa					1048:1059	the range 500-2000 kDa	1038:1059	the range 500-2000 kDa	1038:1059	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	8	7	link	cross-linked	1641:1652	arg1	material					1654:1661	the range 500-2000 kDa and cross-linked material	1614:1661	the range 500-2000 kDa and cross-linked material without CS	1614:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	7	8	theme	model	1247:1251	arg1	SF					1256:1257	model OA SF	1247:1257	model OA SF	1247:1257	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	6	9	from	weights	1027:1033	arg1	devices					1107:1113	medical devices	1099:1113	medical devices	1099:1113	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	6	9	from	weights	1027:1033	arg1	500-2000 kDa					1048:1059	the range 500-2000 kDa	1038:1059	the range 500-2000 kDa	1038:1059	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	8	10	theme	molecular	1594:1602	arg1	weight					1604:1609	molecular weight	1594:1609	molecular weight in the range 500-2000 kDa and cross-linked material without CS	1594:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	2	11	theme	properties	281:290	arg1	loss					243:246	the loss	239:246	the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	239:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	7	12	theme	scientific	1192:1201	arg1	literature					1203:1212	scientific literature	1192:1212	scientific literature	1192:1212	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	2	13	theme	tribological	268:279	arg1	properties					281:290	viscoelastic and tribological properties	251:290	viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	251:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	4	14	theme	therapeutic	561:571	arg1	effect					573:578	only temporal therapeutic effect	547:578	only temporal therapeutic effect	547:578	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
35727166	5	15	theme	cross-linked	705:716	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	6	16	theme	viscosupplementation	1119:1138	arg1	treatment					1140:1148	viscosupplementation treatment	1119:1148	viscosupplementation treatment	1119:1148	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	5	17	theme	weight	790:795	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	8	18	with	solutions	1579:1587	arg1	weight					1604:1609	molecular weight	1594:1609	molecular weight in the range 500-2000 kDa and cross-linked material without CS	1594:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	19	theme	observed	1355:1362	arg1	results					1364:1370	The observed results	1351:1370	The observed results	1351:1370	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	5	20	theme	online	803:808	arg1	determination					810:822	online determination	803:822	online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase	803:898	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	5	21	theme	tyramine	718:725	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	6	22	theme	HA	989:990	arg1	solutions					992:1000	HA solutions	989:1000	HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment	989:1148	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	8	23	theme	HA	1576:1577	arg1	solutions					1579:1587	HA solutions	1576:1587	HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS	1576:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	2	24	theme	viscoelastic	251:262	arg1	properties					281:290	viscoelastic and tribological properties	251:290	viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	251:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	1	25	theme	common	164:169	arg1	disorders					187:195	the most common musculoskeletal disorders	155:195	the most common musculoskeletal disorders in the world	155:208	Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world.					
35727166	0	26	theme	composite	2:10	arg1	device					12:17	A composite device	0:17	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase	0:122	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase.					
35727166	6	27	theme	viscosupplement	954:968	arg1	properties					930:939	Rheological and tribological properties	901:939	properties	930:939	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	7	28	theme	clinical	1170:1177	arg1	practice					1179:1186	clinical practice	1170:1186	clinical practice	1170:1186	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	1	29	theme	musculoskeletal	171:185	arg1	disorders					187:195	the most common musculoskeletal disorders	155:195	the most common musculoskeletal disorders in the world	155:208	Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world.					
35727166	8	30	theme	healthy	1491:1497	arg1	SF					1499:1500	healthy SF	1491:1500	healthy SF	1491:1500	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	4	31	theme	viscosupplementation	509:528	arg1	products					530:537	current viscosupplementation products	501:537	current viscosupplementation products	501:537	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
35727166	2	32	theme	fluid	304:308	arg1	properties					281:290	viscoelastic and tribological properties	251:290	viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	251:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	1	33	theme	disorders	187:195	arg1	one					148:150	one	148:150	one	148:150	Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world.					
35727166	1	33	theme	disorders	187:195	arg1	disorders					187:195	the most common musculoskeletal disorders	155:195	the most common musculoskeletal disorders in the world	155:208	Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world.					
35727166	4	34	theme	current	501:507	arg1	products					530:537	current viscosupplementation products	501:537	current viscosupplementation products	501:537	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
35727166	5	35	dep	HA	741:742	arg1	HA					797:798	HA	797:798	HA	797:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	8	36	with	comparable	1475:1484	arg1	SF					1499:1500	healthy SF	1491:1500	healthy SF	1491:1500	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	2	37	theme	synovial	295:302	arg1	SF					311:312	SF	311:312	SF	311:312	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	2	37	theme	synovial	295:302	arg1	fluid					304:308	synovial fluid	295:308	synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	295:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	5	38	theme	molecular	780:788	arg1	weight					790:795	high molecular weight	775:795	high molecular weight	775:795	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	5	39	theme	high	775:778	arg1	weight					790:795	high molecular weight	775:795	high molecular weight	775:795	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	8	40	dep	viscosity	1435:1443	arg1	moduli					1467:1472	elastic, and viscous moduli	1446:1472	elastic, and viscous moduli	1446:1472	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	5	41	theme	properties	840:849	arg1	determination					810:822	online determination	803:822	online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase	803:898	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	5	42	theme	chondroitin	745:755	arg1	CS					766:767	CS	766:767	CS	766:767	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	5	42	theme	chondroitin	745:755	arg1	sulfate					757:763	chondroitin sulfate	745:763	chondroitin sulfate (CS)	745:768	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	7	43	theme	OA	1253:1254	arg1	SF					1256:1257	model OA SF	1247:1257	model OA SF	1247:1257	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	5	44	theme	viscoelastic	827:838	arg1	properties					840:849	viscoelastic properties	827:849	viscoelastic properties loss during degradation by ROS and hyaluronidase	827:898	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	2	45	theme	oxygen	370:375	arg1	ROS					386:388	ROS	386:388	ROS	386:388	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	2	45	theme	oxygen	370:375	arg1	species					377:383	reactive oxygen species	361:383	reactive oxygen species (ROS)	361:389	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	0	46	theme	viscosupplementation	23:42	arg1	treatment					44:52	viscosupplementation treatment	23:52	viscosupplementation treatment	23:52	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase.					
35727166	6	47	theme	tribological	917:928	arg1	properties					930:939	Rheological and tribological properties	901:939	properties	930:939	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	5	48	theme	sulfate	757:763	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	7	49	theme	final	1304:1308	arg1	properties					1310:1319	final properties	1304:1319	final properties	1304:1319	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	6	50	with	solutions	992:1000	arg1	weights					1027:1033	different molecular weights	1007:1033	different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment	1007:1148	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	2	51	theme	reactive	361:368	arg1	ROS					386:388	ROS	386:388	ROS	386:388	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	2	51	theme	reactive	361:368	arg1	species					377:383	reactive oxygen species	361:383	reactive oxygen species (ROS)	361:389	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	8	52	theme	longer	1559:1564	arg1	time					1566:1569	a significantly longer time	1543:1569	a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS	1543:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	5	53	theme	novel	649:653	arg1	device					655:660	a novel device	647:660	a novel device for viscosupplementation (NV)	647:690	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	6	54	theme	developed	944:952	arg1	viscosupplement					954:968	developed viscosupplement	944:968	developed viscosupplement	944:968	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	3	55	theme	ways	446:449	arg1	ways					446:449	the ways	442:449	the ways how to effectively restore SF functions	442:489	Viscosupplementation is one of the ways how to effectively restore SF functions.					
35727166	3	55	theme	ways	446:449	arg1	one					435:437	one	435:437	one	435:437	Viscosupplementation is one of the ways how to effectively restore SF functions.					
35727166	0	56	theme	resistant	54:62	arg1	device					12:17	A composite device	0:17	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase	0:122	A composite device for viscosupplementation treatment resistant to degradation by reactive oxygen species and hyaluronidase.					
35727166	6	57	theme	Rheological	901:911	arg1	properties					930:939	Rheological and tribological properties	901:939	properties	930:939	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	6	58	used	used	1091:1094	arg2	devices					1107:1113	medical devices	1099:1113	medical devices	1099:1113	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	6	58	used	used	1091:1094	arg2	500-2000 kDa					1048:1059	the range 500-2000 kDa	1038:1059	the range 500-2000 kDa	1038:1059	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	8	59	theme	elastic	1446:1452	arg1	moduli					1467:1472	elastic, and viscous moduli	1446:1472	elastic, and viscous moduli	1446:1472	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	60	theme	rheological	1411:1421	arg1	viscosity					1435:1443	viscosity	1435:1443	viscosity	1435:1443	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	60	theme	rheological	1411:1421	arg1	properties					1423:1432	appropriate rheological properties	1399:1432	appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF	1399:1500	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	61	theme	appropriate	1399:1409	arg1	viscosity					1435:1443	viscosity	1435:1443	viscosity	1435:1443	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	61	theme	appropriate	1399:1409	arg1	properties					1423:1432	appropriate rheological properties	1399:1432	appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF	1399:1500	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	5	62	dep	properties	840:849	arg1	loss					851:854	loss	851:854	loss	851:854	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	6	63	theme	molecular	1017:1025	arg1	weights					1027:1033	different molecular weights	1007:1033	different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment	1007:1148	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	7	64	theme	ratio	1266:1270	arg1	vol/vol					1277:1283	vol/vol	1277:1283	vol/vol	1277:1283	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	7	64	theme	ratio	1266:1270	arg1	1:1					1272:1274	the ratio 1:1	1262:1274	the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint	1262:1348	Moreover, based on clinical practice and scientific literature all samples were also diluted by model OA SF in the ratio 1:1 (vol/vol) to better predict final properties after injection to the joint.					
35727166	5	65	link	cross-linked	705:716	arg1	derivative					727:736	the cross-linked tyramine derivative	701:736	the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA	701:798	In this article we describe a novel device for viscosupplementation (NV) based on the cross-linked tyramine derivative of HA, chondroitin sulfate (CS), and high molecular weight HA by online determination of viscoelastic properties loss during degradation by ROS and hyaluronidase.					
35727166	2	66	theme	hyaluronic	337:346	arg1	HA					354:355	HA	354:355	HA	354:355	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	2	66	theme	hyaluronic	337:346	arg1	acid					348:351	hyaluronic acid	337:351	hyaluronic acid (HA)	337:356	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	6	67	theme	different	1007:1015	arg1	weights					1027:1033	different molecular weights	1007:1033	different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment	1007:1148	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	8	68	theme	viscous	1459:1465	arg1	moduli					1467:1472	elastic, and viscous moduli	1446:1472	elastic, and viscous moduli	1446:1472	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	1	69	from	disorders	187:195	arg1	world					204:208	the world	200:208	the world	200:208	Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world.					
35727166	2	70	theme	acid	348:351	arg1	degradation					322:332	degradation	322:332	degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases	322:408	OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases.					
35727166	8	71	theme	500-2000 kDa	1624:1635	arg1	material					1654:1661	the range 500-2000 kDa and cross-linked material	1614:1661	the range 500-2000 kDa and cross-linked material without CS	1614:1672	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	4	72	theme	biological	597:606	arg1	half-life					608:616	short biological half-life	591:616	short biological half-life	591:616	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
35727166	8	73	theme	comparable	1475:1484	arg1	viscosity					1435:1443	viscosity	1435:1443	viscosity	1435:1443	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	8	73	theme	comparable	1475:1484	arg1	properties					1423:1432	appropriate rheological properties	1399:1432	appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF	1399:1500	The observed results confirmed that NV exhibits appropriate rheological properties (viscosity, elastic, and viscous moduli) comparable with healthy SF and maintain them during degradation for a significantly longer time than HA solutions with molecular weight in the range 500-2000 kDa and cross-linked material without CS.					
35727166	6	74	theme	medical	1099:1105	arg1	devices					1107:1113	medical devices	1099:1113	medical devices	1099:1113	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	6	74	theme	medical	1099:1105	arg1	500-2000 kDa					1048:1059	the range 500-2000 kDa	1038:1059	the range 500-2000 kDa	1038:1059	Rheological and tribological properties of developed viscosupplement were compared with HA solutions with different molecular weights in the range 500-2000 kDa, which are currently commonly used as medical devices for viscosupplementation treatment.					
35727166	3	75	theme	SF	478:479	arg1	functions					481:489	SF functions	478:489	SF functions	478:489	Viscosupplementation is one of the ways how to effectively restore SF functions.					
35727166	4	76	theme	short	591:595	arg1	half-life					608:616	short biological half-life	591:616	short biological half-life	591:616	However, current viscosupplementation products provide only temporal therapeutic effect because of short biological half-life.					
36184513	9	0	theme	cell	1245:1248	arg1	membrane					1250:1257	the cell membrane	1241:1257	the cell membrane	1241:1257	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	1	1	theme	cell	142:145	arg1	properties					156:165	excellent cell adhesion properties	132:165	excellent cell adhesion properties	132:165	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	7	2	theme	hydrophobic	840:850	arg1	XR8-matrices					852:863	hydrophobic XR8-matrices	840:863	hydrophobic XR8-matrices	840:863	However, hydrophobic XR8-matrices tended to promote cell proliferation to a less extent.					
36184513	4	3	theme	residues	545:552	arg1	half					512:515	half	512:515	half of the original R8 arginine residues	512:552	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	0	4	theme	Octa-arginine	65:77	arg1	Properties					51:60	Cell Adhesion Properties	37:60	Cell Adhesion Properties of Octa-arginine	37:77	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	1	5	theme	adhesion	147:154	arg1	properties					156:165	excellent cell adhesion properties	132:165	excellent cell adhesion properties	132:165	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	4	6	theme	arginine	536:543	arg1	residues					545:552	the original R8 arginine residues	520:552	the original R8 arginine residues	520:552	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	0	7	from	Effect	0:5	arg1	Properties					51:60	Cell Adhesion Properties	37:60	Cell Adhesion Properties of Octa-arginine	37:77	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	6	8	theme	amino	819:823	arg1	X					787:787	X	787:787	X	787:787	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	6	8	theme	amino	819:823	arg1	acid					825:828	a hydrophobic or aromatic amino acid	793:828	a hydrophobic or aromatic amino acid	793:828	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	6	9	theme	cell	766:769	arg1	attachment					771:780	slightly better cell attachment	750:780	slightly better cell attachment	750:780	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	2	10	theme	integrin	286:293	arg1	β1					295:296	integrin β1	286:296	integrin β1	286:296	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	6	11	theme	better	759:764	arg1	attachment					771:780	slightly better cell attachment	750:780	slightly better cell attachment	750:780	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	1	12	with	peptide	119:125	arg1	properties					156:165	excellent cell adhesion properties	132:165	excellent cell adhesion properties	132:165	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	8	13	theme	cell	969:972	arg1	adhesion					974:981	cell adhesion	969:981	cell adhesion	969:981	Eventually, YR8-matrix most efficiently promoted cell adhesion, spreading, and proliferation among the XR8-matrices tested.					
36184513	7	14	theme	less	907:910	arg1	extent					912:917	a less extent	905:917	a less extent	905:917	However, hydrophobic XR8-matrices tended to promote cell proliferation to a less extent.					
36184513	9	15	theme	XR8-matrices	1167:1178	arg1	activity					1155:1162	the biological activity	1140:1162	the biological activity of XR8-matrices	1140:1178	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	3	16	theme	specific	408:415	arg1	composition					425:435	specific peptide composition	408:435	specific peptide composition	408:435	However, it is not clear how these properties are affected by specific peptide composition and if they could be improved.					
36184513	7	17	theme	cell	883:886	arg1	proliferation					888:900	cell proliferation	883:900	cell proliferation	883:900	However, hydrophobic XR8-matrices tended to promote cell proliferation to a less extent.					
36184513	10	18	theme	promising	1278:1286	arg1	peptide					1302:1308	a promising cell-adhesive peptide	1276:1308	a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials	1276:1372	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	10	18	theme	promising	1278:1286	arg1	YR8					1269:1271	YR8	1269:1271	YR8	1269:1271	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	3	19	theme	peptide	417:423	arg1	composition					425:435	specific peptide composition	408:435	specific peptide composition	408:435	However, it is not clear how these properties are affected by specific peptide composition and if they could be improved.					
36184513	0	20	theme	Acid	16:19	arg1	Substitution					21:32	Amino Acid Substitution	10:32	Amino Acid Substitution	10:32	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	10	21	theme	cell	1333:1336	arg1	substrates					1346:1355	cell culture substrates	1333:1355	cell culture substrates	1333:1355	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	0	22	theme	Amino	10:14	arg1	Substitution					21:32	Amino Acid Substitution	10:32	Amino Acid Substitution	10:32	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	4	23	theme	R8	533:534	arg1	residues					545:552	the original R8 arginine residues	520:552	the original R8 arginine residues	520:552	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	5	24	theme	substitution	644:655	arg1	effect					630:635	the effect	626:635	the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices	626:725	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	4	25	theme	XR8	489:491	arg1	peptides					493:500	XR8 peptides	489:500	XR8 peptides	489:500	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	4	26	theme	original	524:531	arg1	residues					545:552	the original R8 arginine residues	520:552	the original R8 arginine residues	520:552	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	2	27	theme	Surface-immobilized	168:186	arg1	R8					188:189	Surface-immobilized R8	168:189	Surface-immobilized R8	168:189	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	0	28	theme	Substitution	21:32	arg1	Effect					0:5	Effect	0:5	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.	0:78	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	5	29	theme	cell	660:663	arg1	adhesion					665:672	cell adhesion	660:672	cell adhesion	660:672	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	6	30	theme	aromatic	810:817	arg1	X					787:787	X	787:787	X	787:787	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	6	30	theme	aromatic	810:817	arg1	acid					825:828	a hydrophobic or aromatic amino acid	793:828	a hydrophobic or aromatic amino acid	793:828	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	0	31	theme	Adhesion	42:49	arg1	Properties					51:60	Cell Adhesion Properties	37:60	Cell Adhesion Properties of Octa-arginine	37:77	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	9	32	theme	biological	1144:1153	arg1	activity					1155:1162	the biological activity	1140:1162	the biological activity of XR8-matrices	1140:1178	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	2	33	theme	surface	225:231	arg1	receptors					233:241	cell surface receptors	220:241	cell surface receptors	220:241	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	33	theme	surface	225:231	arg1	proteoglycans					268:280	heparan sulfate proteoglycans	252:280	heparan sulfate proteoglycans	252:280	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	33	theme	surface	225:231	arg1	β1					295:296	integrin β1	286:296	integrin β1	286:296	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	10	34	theme	cell-adhesive	1288:1300	arg1	peptide					1302:1308	a promising cell-adhesive peptide	1276:1308	a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials	1276:1372	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	10	34	theme	cell-adhesive	1288:1300	arg1	YR8					1269:1271	YR8	1269:1271	YR8	1269:1271	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	0	35	theme	Cell	37:40	arg1	Properties					51:60	Cell Adhesion Properties	37:60	Cell Adhesion Properties of Octa-arginine	37:77	Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine.					
36184513	10	36	theme	substrates	1346:1355	arg1	development					1318:1328	the development	1314:1328	the development of cell culture substrates and biomaterials	1314:1372	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	6	37	theme	hydrophobic	795:805	arg1	X					787:787	X	787:787	X	787:787	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	6	37	theme	hydrophobic	795:805	arg1	acid					825:828	a hydrophobic or aromatic amino acid	793:828	a hydrophobic or aromatic amino acid	793:828	The XR8-matrix showed slightly better cell attachment when X was a hydrophobic or aromatic amino acid.					
36184513	2	38	theme	cell	220:223	arg1	receptors					233:241	cell surface receptors	220:241	cell surface receptors	220:241	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	38	theme	cell	220:223	arg1	proteoglycans					268:280	heparan sulfate proteoglycans	252:280	heparan sulfate proteoglycans	252:280	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	38	theme	cell	220:223	arg1	β1					295:296	integrin β1	286:296	integrin β1	286:296	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	9	39	theme	residue	1109:1115	arg1	X					1117:1117	residue X	1109:1117	residue X	1109:1117	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	10	40	theme	biomaterials	1361:1372	arg1	development					1318:1328	the development	1314:1328	the development of cell culture substrates and biomaterials	1314:1372	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	9	41	theme	small	1222:1226	arg1	peptides					1228:1235	small peptides	1222:1235	small peptides	1222:1235	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	2	42	theme	sulfate	260:266	arg1	proteoglycans					268:280	heparan sulfate proteoglycans	252:280	heparan sulfate proteoglycans	252:280	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	9	43	theme	X	1117:1117	arg1	properties					1095:1104	the properties	1091:1104	the properties of residue X	1091:1117	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	1	44	theme	cell-permeable	104:117	arg1	peptide					119:125	a cell-permeable peptide	102:125	a cell-permeable peptide with excellent cell adhesion properties	102:165	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	1	44	theme	cell-permeable	104:117	arg1	Octa-arginine					80:92	Octa-arginine	80:92	Octa-arginine (R8)	80:97	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	5	45	from	effect	630:635	arg1	proliferation					678:690	proliferation	678:690	proliferation	678:690	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	5	45	from	effect	630:635	arg1	adhesion					665:672	cell adhesion	660:672	cell adhesion	660:672	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	5	45	from	effect	630:635	arg1	matrices					718:725	XR8-conjugated agarose matrices	695:725	XR8-conjugated agarose matrices	695:725	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	2	46	theme	cell	200:203	arg1	attachment					205:214	cell attachment	200:214	cell attachment	200:214	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	47	theme	heparan	252:258	arg1	proteoglycans					268:280	heparan sulfate proteoglycans	252:280	heparan sulfate proteoglycans	252:280	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	2	48	dep	cell	312:315	arg1	spreading					317:325	spreading	317:325	spreading	317:325	Surface-immobilized R8 mediates cell attachment via cell surface receptors, such as heparan sulfate proteoglycans and integrin β1, and promotes cell spreading and proliferation.					
36184513	5	49	theme	XR8-conjugated	695:708	arg1	matrices					718:725	XR8-conjugated agarose matrices	695:725	XR8-conjugated agarose matrices	695:725	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	10	50	theme	culture	1338:1344	arg1	substrates					1346:1355	cell culture substrates	1333:1355	cell culture substrates	1333:1355	Further, YR8 is a promising cell-adhesive peptide for the development of cell culture substrates and biomaterials.					
36184513	5	51	theme	agarose	710:716	arg1	matrices					718:725	XR8-conjugated agarose matrices	695:725	XR8-conjugated agarose matrices	695:725	We then aimed to investigate the effect of the substitution on cell adhesion and proliferation on XR8-conjugated agarose matrices.					
36184513	9	52	theme	major	1126:1130	arg1	role					1132:1135	a major role	1124:1135	a major role	1124:1135	Collectively, these observations indicate that the properties of residue X play a major role in the biological activity of XR8-matrices and shed light on the interaction between small peptides and the cell membrane.					
36184513	1	53	theme	excellent	132:140	arg1	properties					156:165	excellent cell adhesion properties	132:165	excellent cell adhesion properties	132:165	Octa-arginine (R8) is a cell-permeable peptide with excellent cell adhesion properties.					
36184513	4	54	theme	amino	581:585	arg1	X					593:593	X	593:593	X	593:593	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
36184513	4	54	theme	amino	581:585	arg1	acid					587:590	another amino acid	573:590	another amino acid (X)	573:594	Here, we synthesized XR8 peptides, in which half of the original R8 arginine residues were replaced with another amino acid (X).					
35989404	4	0	theme	methacrylate	492:503	arg1	MOF					505:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	4	0	theme	methacrylate	492:503	arg1	material					457:464	a composite material	445:464	a composite material (chitosan-UiO-66-glycidyl methacrylate MOF)	445:508	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	11	1	theme	novel	1550:1554	arg1	composite					1568:1576	a novel synthesized composite	1548:1576	a novel synthesized composite with enhanced recyclability	1548:1604	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	7	2	with	m2/g	922:925	arg1	volume					945:950	a total pore volume	932:950	a total pore volume of 0.51 cm3/g	932:964	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	2	with	m2/g	922:925	arg1	stability					978:986	thermal stability	970:986	thermal stability of up to 400 [Formula	970:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	5	3	theme	BET	638:640	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	9	4	theme	pseudo-second-order	1282:1300	arg1	equation					1307:1314	the pseudo-second-order rate equation	1278:1314	the pseudo-second-order rate equation	1278:1314	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	6	5	theme	ion	835:837	arg1	concentration					839:851	initial metal ion concentration	821:851	initial metal ion concentration	821:851	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	7	6	theme	[Formula	1001:1008	arg1	volume					945:950	a total pore volume	932:950	a total pore volume of 0.51 cm3/g	932:964	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	6	theme	[Formula	1001:1008	arg1	stability					978:986	thermal stability	970:986	thermal stability of up to 400 [Formula	970:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	7	theme	large	896:900	arg1	area					910:913	a large surface area	894:913	a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula	894:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	2	8	from	entities	284:291	arg1	result					251:256	a result	249:256	a result	249:256	As a result, metal removal from water entities must be addressed soon.					
35989404	2	8	from	entities	284:291	arg1	removal					265:271	metal removal	259:271	metal removal from water entities	259:291	As a result, metal removal from water entities must be addressed soon.					
35989404	9	9	theme	rate	1302:1305	arg1	equation					1307:1314	the pseudo-second-order rate equation	1278:1314	the pseudo-second-order rate equation	1278:1314	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	10	10	theme	consecutive	1442:1452	arg1	cycles					1454:1459	5 consecutive cycles	1440:1459	5 consecutive cycles	1440:1459	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	6	11	theme	metal	829:833	arg1	concentration					839:851	initial metal ion concentration	821:851	initial metal ion concentration	821:851	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	5	12	theme	FT-IR	643:647	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	2	13	theme	metal	259:263	arg1	result					251:256	a result	249:256	a result	249:256	As a result, metal removal from water entities must be addressed soon.					
35989404	2	13	theme	metal	259:263	arg1	removal					265:271	metal removal	259:271	metal removal from water entities	259:291	As a result, metal removal from water entities must be addressed soon.					
35989404	11	14	theme	industrial	1661:1670	arg1	wastewater					1672:1681	industrial wastewater	1661:1681	industrial wastewater	1661:1681	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	3	15	theme	Various	317:323	arg1	chitosan					353:360	chitosan	353:360	chitosan	353:360	Various adsorbents such as MOFs and chitosan have demonstrated promising results in water treatment.					
35989404	3	15	theme	Various	317:323	arg1	adsorbents					325:334	Various adsorbents	317:334	Various adsorbents such as MOFs and chitosan	317:360	Various adsorbents such as MOFs and chitosan have demonstrated promising results in water treatment.					
35989404	3	15	theme	Various	317:323	arg1	MOFs					344:347	MOFs	344:347	MOFs	344:347	Various adsorbents such as MOFs and chitosan have demonstrated promising results in water treatment.					
35989404	4	16	theme	composite	447:455	arg1	MOF					505:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	4	16	theme	composite	447:455	arg1	material					457:464	a composite material	445:464	a composite material (chitosan-UiO-66-glycidyl methacrylate MOF)	445:508	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	8	17	theme	adsorption	1051:1060	arg1	isotherms					1062:1070	the adsorption isotherms	1047:1070	the adsorption isotherms	1047:1070	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	5	18	theme	FE-SEM	620:625	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	0	19	dep	adsorption	80:89	arg1	Insight					0:6	Insight	0:6	Insight into microwave-assisted synthesis of the chitosan-MOF composite	0:70	Insight into microwave-assisted synthesis of the chitosan-MOF composite: Pb(II) adsorption.					
35989404	1	20	theme	environmental	168:180	arg1	issues					182:187	significant environmental issues	156:187	significant environmental issues owing to direct and indirect releases into water bodies	156:243	Heavy metal contamination has increased over the globe, causing significant environmental issues owing to direct and indirect releases into water bodies.					
35989404	0	21	theme	chitosan-MOF	49:60	arg1	composite					62:70	the chitosan-MOF composite	45:70	the chitosan-MOF composite	45:70	Insight into microwave-assisted synthesis of the chitosan-MOF composite: Pb(II) adsorption.					
35989404	4	22	theme	chitosan-UiO-66-glycidyl	467:490	arg1	MOF					505:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	chitosan-UiO-66-glycidyl methacrylate MOF	467:507	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	4	22	theme	chitosan-UiO-66-glycidyl	467:490	arg1	material					457:464	a composite material	445:464	a composite material (chitosan-UiO-66-glycidyl methacrylate MOF)	445:508	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	5	23	theme	EDX	628:630	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	1	24	theme	significant	156:166	arg1	issues					182:187	significant environmental issues	156:187	significant environmental issues owing to direct and indirect releases into water bodies	156:243	Heavy metal contamination has increased over the globe, causing significant environmental issues owing to direct and indirect releases into water bodies.					
35989404	6	25	theme	initial	821:827	arg1	concentration					839:851	initial metal ion concentration	821:851	initial metal ion concentration	821:851	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	10	26	theme	effectiveness	1420:1432	arg1	effectiveness					1420:1432	its removal effectiveness	1408:1432	its removal effectiveness	1408:1432	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	10	26	theme	effectiveness	1420:1432	arg1	%					1403:1403	83.45%	1398:1403	83.45% of its removal effectiveness	1398:1432	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	5	27	dep	structure	546:554	arg1	The					542:544	The	542:544	The	542:544	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	3	28	theme	water	401:405	arg1	treatment					407:415	water treatment	401:415	water treatment	401:415	Various adsorbents such as MOFs and chitosan have demonstrated promising results in water treatment.					
35989404	8	29	theme	isotherms	1062:1070	arg1	kinetics					1073:1080	kinetics	1073:1080	kinetics	1073:1080	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	29	theme	isotherms	1062:1070	arg1	thermodynamics					1087:1100	thermodynamics	1087:1100	thermodynamics	1087:1100	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	29	theme	isotherms	1062:1070	arg1	analysis					1035:1042	an analysis	1032:1042	an analysis of the adsorption isotherms	1032:1070	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	5	30	theme	XRD	633:635	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	5	31	theme	chitosan-MOF	578:589	arg1	composite					591:599	the chitosan-MOF composite	574:599	the chitosan-MOF composite	574:599	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	10	32	theme	metal	1510:1514	arg1	recovery					1516:1523	metal recovery	1510:1523	metal recovery	1510:1523	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	7	33	theme	thermal	970:976	arg1	stability					978:986	thermal stability	970:986	thermal stability of up to 400 [Formula	970:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	5	34	theme	composite	591:599	arg1	structure					546:554	structure	546:554	structure	546:554	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	5	34	theme	composite	591:599	arg1	morphology					560:569	morphology	560:569	morphology	560:569	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	2	35	theme	water	278:282	arg1	entities					284:291	water entities	278:291	water entities	278:291	As a result, metal removal from water entities must be addressed soon.					
35989404	11	36	with	composite	1568:1576	arg1	recyclability					1592:1604	enhanced recyclability	1583:1604	enhanced recyclability	1583:1604	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	6	37	from	solution	721:728	arg1	adsorption					687:696	the adsorption	683:696	the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite	683:760	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	0	38	theme	microwave-assisted	13:30	arg1	synthesis					32:40	microwave-assisted synthesis	13:40	microwave-assisted synthesis of the chitosan-MOF composite	13:70	Insight into microwave-assisted synthesis of the chitosan-MOF composite: Pb(II) adsorption.					
35989404	7	39	theme	pore	940:943	arg1	volume					945:950	a total pore volume	932:950	a total pore volume of 0.51 cm3/g	932:964	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	6	40	theme	contact	807:813	arg1	time					815:818	contact time	807:818	contact time	807:818	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	1	41	theme	Heavy	92:96	arg1	contamination					104:116	Heavy metal contamination	92:116	Heavy metal contamination	92:116	Heavy metal contamination has increased over the globe, causing significant environmental issues owing to direct and indirect releases into water bodies.					
35989404	8	42	theme	excellent	1132:1140	arg1	fit					1142:1144	an excellent fit	1129:1144	an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609)	1129:1210	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	7	43	contain	has	890:892	arg2	area					910:913	a large surface area	894:913	a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula	894:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	43	contain	has	890:892	arg1	composite					880:888	The composite	876:888	The composite	876:888	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	44	theme	cm3/g	960:964	arg1	volume					945:950	a total pore volume	932:950	a total pore volume of 0.51 cm3/g	932:964	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	7	44	theme	cm3/g	960:964	arg1	stability					978:986	thermal stability	970:986	thermal stability of up to 400 [Formula	970:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	4	45	theme	present	422:428	arg1	study					430:434	The present study	418:434	The present study	418:434	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	11	46	theme	enhanced	1583:1590	arg1	recyclability					1592:1604	enhanced recyclability	1583:1604	enhanced recyclability	1583:1604	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	8	47	theme	Langmuir	1107:1114	arg1	model					1116:1120	the Langmuir model	1103:1120	the Langmuir model	1103:1120	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	4	48	theme	microwave-assisted	515:532	arg1	method					534:539	a microwave-assisted method	513:539	a microwave-assisted method	513:539	The present study prepared a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) by a microwave-assisted method.					
35989404	10	49	theme	adsorbent	1496:1504	arg1	it					1476:1477	it	1476:1477	it	1476:1477	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	10	49	theme	adsorbent	1496:1504	arg1	sustainable					1484:1494	a sustainable	1482:1494	a sustainable adsorbent for metal recovery	1482:1523	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	11	50	theme	synthesized	1556:1566	arg1	composite					1568:1576	a novel synthesized composite	1548:1576	a novel synthesized composite with enhanced recyclability	1548:1604	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	8	51	with	fit	1142:1144	arg1	X2 = 3.609					1200:1209	X2 = 3.609	1200:1209	X2 = 3.609	1200:1209	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	51	with	fit	1142:1144	arg1	R2 = 0.99					1172:1180	R2 = 0.99	1172:1180	R2 = 0.99	1172:1180	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	51	with	fit	1142:1144	arg1	chi-squared					1187:1197	chi-squared	1187:1197	chi-squared	1187:1197	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	51	with	fit	1142:1144	arg1	data					1166:1169	the adsorption data	1151:1169	the adsorption data (R2 = 0.99)	1151:1181	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	0	52	theme	composite	62:70	arg1	synthesis					32:40	microwave-assisted synthesis	13:40	microwave-assisted synthesis of the chitosan-MOF composite	13:70	Insight into microwave-assisted synthesis of the chitosan-MOF composite: Pb(II) adsorption.					
35989404	9	53	theme	adsorption	1217:1226	arg1	reaction					1265:1272	a spontaneous exothermic reaction	1240:1272	a spontaneous exothermic reaction	1240:1272	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	9	53	theme	adsorption	1217:1226	arg1	process					1228:1234	The adsorption process	1213:1234	The adsorption process	1213:1234	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	6	54	theme	aqueous	713:719	arg1	solution					721:728	aqueous solution	713:728	aqueous solution	713:728	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	1	55	theme	metal	98:102	arg1	contamination					104:116	Heavy metal contamination	92:116	Heavy metal contamination	92:116	Heavy metal contamination has increased over the globe, causing significant environmental issues owing to direct and indirect releases into water bodies.					
35989404	3	56	theme	promising	380:388	arg1	results					390:396	promising results	380:396	promising results	380:396	Various adsorbents such as MOFs and chitosan have demonstrated promising results in water treatment.					
35989404	11	57	theme	higher	1612:1617	arg1	potential					1619:1627	a higher potential	1610:1627	a higher potential for eliminating pollutants from industrial wastewater	1610:1681	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	7	58	theme	m2/g	922:925	arg1	area					910:913	a large surface area	894:913	a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula	894:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	8	59	theme	adsorption	1155:1164	arg1	R2 = 0.99					1172:1180	R2 = 0.99	1172:1180	R2 = 0.99	1172:1180	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	8	59	theme	adsorption	1155:1164	arg1	data					1166:1169	the adsorption data	1151:1169	the adsorption data (R2 = 0.99)	1151:1181	Following an analysis of the adsorption isotherms, kinetics, and thermodynamics, the Langmuir model showed an excellent fit with the adsorption data (R2 = 0.99) and chi-squared (X2 = 3.609).					
35989404	6	60	theme	adsorbent	858:866	arg1	dosage					868:873	adsorbent dosage	858:873	adsorbent dosage	858:873	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	5	61	theme	TGA	654:656	arg1	techniques					658:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques	620:667	The structure and morphology of the chitosan-MOF composite were studied using FE-SEM, EDX, XRD, BET, FT-IR, and TGA techniques.					
35989404	6	62	theme	batch	780:784	arg1	study					786:790	a batch study	778:790	a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage	778:873	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	9	63	theme	spontaneous	1242:1252	arg1	reaction					1265:1272	a spontaneous exothermic reaction	1240:1272	a spontaneous exothermic reaction	1240:1272	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	9	63	theme	spontaneous	1242:1252	arg1	process					1228:1234	The adsorption process	1213:1234	The adsorption process	1213:1234	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	7	64	theme	total	934:938	arg1	volume					945:950	a total pore volume	932:950	a total pore volume of 0.51 cm3/g	932:964	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	6	65	theme	Pb	701:702	arg1	adsorption					687:696	the adsorption	683:696	the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite	683:760	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	9	66	theme	kinetic	1327:1333	arg1	profile					1335:1341	the kinetic profile	1323:1341	the kinetic profile	1323:1341	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	6	67	theme	chitosan-MOF	739:750	arg1	composite					752:760	the chitosan-MOF composite	735:760	the chitosan-MOF composite	735:760	In addition, the adsorption of Pb(II) from aqueous solution onto the chitosan-MOF composite was analyzed in a batch study concerning pH, contact time, initial metal ion concentration, and adsorbent dosage.					
35989404	9	68	theme	exothermic	1254:1263	arg1	reaction					1265:1272	a spontaneous exothermic reaction	1240:1272	a spontaneous exothermic reaction	1240:1272	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	9	68	theme	exothermic	1254:1263	arg1	process					1228:1234	The adsorption process	1213:1234	The adsorption process	1213:1234	The adsorption process was a spontaneous exothermic reaction and the pseudo-second-order rate equation fitted the kinetic profile well.					
35989404	0	69	theme	Pb	73:74	arg1	adsorption					80:89	Pb(II) adsorption	73:89	Pb(II) adsorption	73:89	Insight into microwave-assisted synthesis of the chitosan-MOF composite: Pb(II) adsorption.					
35989404	11	70	with	potential	1619:1627	arg1	recyclability					1592:1604	enhanced recyclability	1583:1604	enhanced recyclability	1583:1604	This study introduces a novel synthesized composite with enhanced recyclability and a higher potential for eliminating pollutants from industrial wastewater.					
35989404	7	71	dep	400	997:999	arg1	to					994:995	to	994:995	to	994:995	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	10	72	theme	removal	1412:1418	arg1	effectiveness					1420:1432	its removal effectiveness	1408:1432	its removal effectiveness	1408:1432	Moreover, the composite is recyclable, retaining 83.45% of its removal effectiveness after 5 consecutive cycles, demonstrating it as a sustainable adsorbent for metal recovery.					
35989404	7	73	theme	surface	902:908	arg1	area					910:913	a large surface area	894:913	a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula	894:1008	The composite has a large surface area of 867 m2/g with a total pore volume of 0.51 cm3/g and thermal stability of up to 400 [Formula: see text].					
35989404	1	74	theme	water	232:236	arg1	bodies					238:243	water bodies	232:243	water bodies	232:243	Heavy metal contamination has increased over the globe, causing significant environmental issues owing to direct and indirect releases into water bodies.					
35952638	8	0	theme	moldable	1208:1215	arg1	properties					1232:1241	the characteristic moldable and injectable properties	1189:1241	the characteristic moldable and injectable properties	1189:1241	In addition, the characteristic moldable and injectable properties made ETAC a promising scaffold for clinical applications.					
35952638	6	1	theme	defect	966:971	arg1	site					973:976	the defect site	962:976	the defect site	962:976	Although the group TAC also produced noticeable bone in the defect site, the healing quality was improved and regeneration was faster after adding ECM.					
35952638	5	2	theme	cancellous	836:845	arg1	bone					847:850	cancellous bone	836:850	cancellous bone	836:850	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
35952638	2	3	theme	β-TCP	392:396	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	8	4	theme	injectable	1221:1230	arg1	properties					1232:1241	the characteristic moldable and injectable properties	1189:1241	the characteristic moldable and injectable properties	1189:1241	In addition, the characteristic moldable and injectable properties made ETAC a promising scaffold for clinical applications.					
35952638	6	5	theme	group	919:923	arg1	TAC					925:927	the group TAC	915:927	the group TAC	915:927	Although the group TAC also produced noticeable bone in the defect site, the healing quality was improved and regeneration was faster after adding ECM.					
35952638	2	6	theme	nanocellulose	313:325	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	7	theme	hydrogel	347:354	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	0	8	link	tissue-derived	6:19	arg1	ECM					21:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	6	9	from	bone	954:957	arg1	site					973:976	the defect site	962:976	the defect site	962:976	Although the group TAC also produced noticeable bone in the defect site, the healing quality was improved and regeneration was faster after adding ECM.					
35952638	6	10	theme	noticeable	943:952	arg1	bone					954:957	noticeable bone	943:957	noticeable bone in the defect site	943:976	Although the group TAC also produced noticeable bone in the defect site, the healing quality was improved and regeneration was faster after adding ECM.					
35952638	5	11	theme	defect	865:870	arg1	model					872:876	the femur defect model	855:876	the femur defect model of rabbits	855:887	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
35952638	2	12	theme	composite	292:300	arg1	beads					302:306	such composite beads	287:306	such composite beads	287:306	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	8	13	theme	promising	1255:1263	arg1	scaffold					1265:1272	a promising scaffold	1253:1272	a promising scaffold for clinical applications	1253:1298	In addition, the characteristic moldable and injectable properties made ETAC a promising scaffold for clinical applications.					
35952638	1	14	theme	engineering	197:207	arg1	edge					182:185	a competitive edge	168:185	a competitive edge of tissue engineering due to faster and more consistent healing	168:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	1	14	theme	engineering	197:207	arg1	regeneration					122:133	Guided bone regeneration	110:133	Guided bone regeneration with osteoinductive scaffolds	110:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	3	15	contain	containing	523:532	arg1	group					517:521	the beads' group	506:521	the beads' group containing ECM-β-TCP-alginate-nanocellulose (ETAC)	506:572	Interestingly, it was observed that the beads' group containing ECM-β-TCP-alginate-nanocellulose (ETAC) was more cytocompatible than the others comprised ofβ-TCP-alginate-nanocellulose (TAC) and alginate-nanocellulose (AC).					
35952638	3	15	contain	containing	523:532	arg2	ETAC					568:571	ETAC	568:571	ETAC	568:571	Interestingly, it was observed that the beads' group containing ECM-β-TCP-alginate-nanocellulose (ETAC) was more cytocompatible than the others comprised ofβ-TCP-alginate-nanocellulose (TAC) and alginate-nanocellulose (AC).					
35952638	3	15	contain	containing	523:532	arg2	ECM-β-TCP-alginate-nanocellulose					534:565	ECM-β-TCP-alginate-nanocellulose	534:565	ECM-β-TCP-alginate-nanocellulose (ETAC)	534:572	Interestingly, it was observed that the beads' group containing ECM-β-TCP-alginate-nanocellulose (ETAC) was more cytocompatible than the others comprised ofβ-TCP-alginate-nanocellulose (TAC) and alginate-nanocellulose (AC).					
35952638	7	16	theme	x-ray	1153:1157	arg1	microtomography					1159:1173	x-ray microtomography	1153:1173	x-ray microtomography	1153:1173	This conclusion was not only confirmed by micro-anatomical analysis but also demonstrated with x-ray microtomography.					
35952638	2	17	theme	such	287:290	arg1	beads					302:306	such composite beads	287:306	such composite beads	287:306	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	4	18	theme	ETAC	713:716	arg1	beads					718:722	ETAC beads	713:722	ETAC beads	713:722	Cell attachment on ETAC beads was dramatically increased with time.					
35952638	0	19	theme	tissue-derived	6:19	arg1	ECM					21:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	8	20	theme	characteristic	1193:1206	arg1	properties					1232:1241	the characteristic moldable and injectable properties	1189:1241	the characteristic moldable and injectable properties	1189:1241	In addition, the characteristic moldable and injectable properties made ETAC a promising scaffold for clinical applications.					
35952638	1	21	theme	Guided	110:115	arg1	edge					182:185	a competitive edge	168:185	a competitive edge of tissue engineering due to faster and more consistent healing	168:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	1	21	theme	Guided	110:115	arg1	regeneration					122:133	Guided bone regeneration	110:133	Guided bone regeneration with osteoinductive scaffolds	110:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	2	22	theme	extracellular	429:441	arg1	matrix					443:448	liver-derived extracellular matrix	415:448	liver-derived extracellular matrix (ECM)	415:454	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	22	theme	extracellular	429:441	arg1	ECM					451:453	ECM	451:453	ECM	451:453	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	0	23	theme	Liver	0:4	arg1	ECM					21:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM	0:23	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	8	24	theme	clinical	1278:1285	arg1	applications					1287:1298	clinical applications	1278:1298	clinical applications	1278:1298	In addition, the characteristic moldable and injectable properties made ETAC a promising scaffold for clinical applications.					
35952638	1	25	theme	bone	117:120	arg1	edge					182:185	a competitive edge	168:185	a competitive edge of tissue engineering due to faster and more consistent healing	168:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	1	25	theme	bone	117:120	arg1	regeneration					122:133	Guided bone regeneration	110:133	Guided bone regeneration with osteoinductive scaffolds	110:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	1	26	theme	faster	216:221	arg1	healing					243:249	faster and more consistent healing	216:249	faster and more consistent healing	216:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	2	27	theme	reinforced	327:336	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	4	28	from	attachment	699:708	arg1	beads					718:722	ETAC beads	713:722	ETAC beads	713:722	Cell attachment on ETAC beads was dramatically increased with time.					
35952638	4	29	theme	Cell	694:697	arg1	attachment					699:708	Cell attachment	694:708	Cell attachment on ETAC beads	694:722	Cell attachment on ETAC beads was dramatically increased with time.					
35952638	2	30	theme	alginate	338:345	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	1	31	theme	tissue	190:195	arg1	engineering					197:207	tissue engineering	190:207	tissue engineering	190:207	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	0	32	theme	composite	59:67	arg1	beads					69:73	nanocellulose-alginate-TCP composite beads	32:73	nanocellulose-alginate-TCP composite beads	32:73	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	2	33	link	liver-derived	415:427	arg1	matrix					443:448	liver-derived extracellular matrix	415:448	liver-derived extracellular matrix (ECM)	415:454	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	33	link	liver-derived	415:427	arg1	ECM					451:453	ECM	451:453	ECM	451:453	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	34	theme	present	259:265	arg1	study					267:271	the present study	255:271	the present study	255:271	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	35	theme	liver-derived	415:427	arg1	matrix					443:448	liver-derived extracellular matrix	415:448	liver-derived extracellular matrix (ECM)	415:454	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	35	theme	liver-derived	415:427	arg1	ECM					451:453	ECM	451:453	ECM	451:453	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	1	36	theme	consistent	232:241	arg1	healing					243:249	faster and more consistent healing	216:249	faster and more consistent healing	216:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	0	37	theme	nanocellulose-alginate-TCP	32:57	arg1	beads					69:73	nanocellulose-alginate-TCP composite beads	32:73	nanocellulose-alginate-TCP composite beads	32:73	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	7	38	theme	micro-anatomical	1100:1115	arg1	analysis					1117:1124	micro-anatomical analysis	1100:1124	micro-anatomical analysis	1100:1124	This conclusion was not only confirmed by micro-anatomical analysis but also demonstrated with x-ray microtomography.					
35952638	6	39	theme	healing	983:989	arg1	quality					991:997	the healing quality	979:997	the healing quality	979:997	Although the group TAC also produced noticeable bone in the defect site, the healing quality was improved and regeneration was faster after adding ECM.					
35952638	5	40	theme	cortical	823:830	arg1	uniform					815:821	uniform cortical	815:830	uniform cortical	815:830	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
35952638	1	41	theme	osteoinductive	140:153	arg1	scaffolds					155:163	osteoinductive scaffolds	140:163	osteoinductive scaffolds	140:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	5	42	theme	femur	859:863	arg1	model					872:876	the femur defect model	855:876	the femur defect model of rabbits	855:887	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
35952638	2	43	theme	phosphate	381:389	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	44	theme	carriedβ-tricalcium	361:379	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	45	theme	that	356:359	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	0	46	theme	bone	91:94	arg1	regeneration					96:107	accelerated bone regeneration	79:107	accelerated bone regeneration	79:107	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	1	47	theme	competitive	170:180	arg1	edge					182:185	a competitive edge	168:185	a competitive edge of tissue engineering due to faster and more consistent healing	168:249	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	1	47	theme	competitive	170:180	arg1	regeneration					122:133	Guided bone regeneration	110:133	Guided bone regeneration with osteoinductive scaffolds	110:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	0	48	theme	accelerated	79:89	arg1	regeneration					96:107	accelerated bone regeneration	79:107	accelerated bone regeneration	79:107	Liver tissue-derived ECM loaded nanocellulose-alginate-TCP composite beads for accelerated bone regeneration.					
35952638	5	49	theme	rabbits	881:887	arg1	model					872:876	the femur defect model	855:876	the femur defect model of rabbits	855:887	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
35952638	2	50	from	porcine	461:467	arg1	matrix					443:448	liver-derived extracellular matrix	415:448	liver-derived extracellular matrix (ECM)	415:454	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	50	from	porcine	461:467	arg1	nano-powder					399:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder	313:409	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	2	50	from	porcine	461:467	arg1	ECM					451:453	ECM	451:453	ECM	451:453	In the present study, we developed such composite beads with nanocellulose reinforced alginate hydrogel that carriedβ-tricalcium phosphate (β-TCP) nano-powder and liver-derived extracellular matrix (ECM) from porcine.					
35952638	1	51	with	regeneration	122:133	arg1	scaffolds					155:163	osteoinductive scaffolds	140:163	osteoinductive scaffolds	140:163	Guided bone regeneration with osteoinductive scaffolds is a competitive edge of tissue engineering due to faster and more consistent healing.					
35952638	5	52	theme	ETAC	795:798	arg1	beads					800:804	ETAC beads	795:804	ETAC beads	795:804	In parallel within vitroresults, ETAC beads produced uniform cortical and cancellous bone in the femur defect model of rabbits within 2 months.					
36446507	5	0	theme	framework	869:877	arg1	materials					879:887	the synthesized dynamic covalent framework materials	836:887	the synthesized dynamic covalent framework materials	836:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	6	1	theme	self-healing	1031:1042	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	4	2	theme	self-healing	777:788	arg1	characteristics					790:804	self-healing characteristics	777:804	self-healing characteristics	777:804	It was demonstrated that the chitosan-based framework materials could undergo a dynamic transamidation reaction to exhibit self-healing characteristics.					
36446507	6	3	theme	novel	987:991	arg1	approach					993:1000	a novel approach	985:1000	a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block	985:1139	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	2	4	theme	acid	405:408	arg1	groups					421:426	residual carboxylic acid functional groups	385:426	residual carboxylic acid functional groups	385:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	6	5	theme	building	1126:1133	arg1	chitosan					1110:1117	chitosan	1110:1117	chitosan	1110:1117	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	6	5	theme	building	1126:1133	arg1	block					1135:1139	the building block	1122:1139	the building block	1122:1139	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	2	6	theme	tripodal	445:452	arg1	reactions					468:476	tripodal cross-linking reactions	445:476	tripodal cross-linking reactions without the need of any catalyst	445:509	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	1	7	theme	one-pot/ultrasonic-assisted	201:227	arg1	reaction					239:246	one-pot/ultrasonic-assisted amidation reaction	201:246	one-pot/ultrasonic-assisted amidation reaction	201:246	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	6	8	theme	biodegradable	1016:1028	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	2	9	theme	carboxylic	394:403	arg1	acid					405:408	residual carboxylic acid	385:408	residual carboxylic acid functional groups	385:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	2	10	theme	Chitosan-based	345:358	arg1	materials					370:378	Chitosan-based framework materials	345:378	Chitosan-based framework materials with residual carboxylic acid functional groups	345:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	3	11	theme	exchange	556:563	arg1	capable					540:546	capable	540:546	capable	540:546	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	3	11	theme	exchange	556:563	arg1	materials					525:533	The obtained materials	512:533	The obtained materials	512:533	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	2	12	theme	framework	360:368	arg1	materials					370:378	Chitosan-based framework materials	345:378	Chitosan-based framework materials with residual carboxylic acid functional groups	345:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	5	13	theme	materials	879:887	arg1	properties					822:831	The structural properties	807:831	The structural properties of the synthesized dynamic covalent framework materials	807:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	2	14	theme	residual	385:392	arg1	acid					405:408	residual carboxylic acid	385:408	residual carboxylic acid functional groups	385:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	5	15	theme	tripodal	940:947	arg1	cross-linkers					949:961	the tripodal cross-linkers	936:961	the tripodal cross-linkers	936:961	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	3	16	theme	participation	587:599	arg1	effect					607:612	neighboring group participation (NGP) effect	569:612	neighboring group participation (NGP) effect	569:612	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	1	17	theme	amidation	229:237	arg1	reaction					239:246	one-pot/ultrasonic-assisted amidation reaction	201:246	one-pot/ultrasonic-assisted amidation reaction	201:246	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	5	18	theme	synthesized	840:850	arg1	materials					879:887	the synthesized dynamic covalent framework materials	836:887	the synthesized dynamic covalent framework materials	836:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	0	19	theme	pH-responsive	14:26	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	3	20	theme	group	581:585	arg1	NGP					602:604	NGP	602:604	NGP	602:604	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	3	20	theme	group	581:585	arg1	participation					587:599	group participation	581:599	neighboring group participation (NGP) effect	569:612	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	1	21	theme	first	102:106	arg1	unit					313:316	the linker unit	302:316	the linker unit	302:316	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	21	theme	first	102:106	arg1	example					108:114	a first example	100:114	a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	100:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	4	22	theme	transamidation	742:755	arg1	reaction					757:764	a dynamic transamidation reaction	732:764	a dynamic transamidation reaction to exhibit self-healing characteristics	732:804	It was demonstrated that the chitosan-based framework materials could undergo a dynamic transamidation reaction to exhibit self-healing characteristics.					
36446507	0	23	theme	Catalyst-free	0:12	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	3	24	theme	dynamic	627:633	arg1	networks					644:651	their dynamic covalent networks	621:651	their dynamic covalent networks	621:651	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	4	25	theme	dynamic	734:740	arg1	reaction					757:764	a dynamic transamidation reaction	732:764	a dynamic transamidation reaction to exhibit self-healing characteristics	732:804	It was demonstrated that the chitosan-based framework materials could undergo a dynamic transamidation reaction to exhibit self-healing characteristics.					
36446507	0	26	theme	dynamic	43:49	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	1	27	theme	linker	306:311	arg1	unit					313:316	the linker unit	302:316	the linker unit	302:316	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	27	theme	linker	306:311	arg1	example					108:114	a first example	100:114	a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	100:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	28	theme	citric	259:264	arg1	acid					266:269	citric acid	259:269	citric acid (CA)	259:274	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	28	theme	citric	259:264	arg1	CA					272:273	CA	272:273	CA	272:273	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	0	29	theme	chitosan-based	28:41	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	6	30	theme	adsorbent	1084:1092	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	2	31	with	materials	370:378	arg1	groups					421:426	residual carboxylic acid functional groups	385:426	residual carboxylic acid functional groups	385:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	1	32	theme	chitosan-based	119:132	arg1	materials					161:169	chitosan-based dynamic covalent framework materials	119:169	chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	119:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	4	33	theme	chitosan-based	683:696	arg1	materials					708:716	the chitosan-based framework materials	679:716	the chitosan-based framework materials	679:716	It was demonstrated that the chitosan-based framework materials could undergo a dynamic transamidation reaction to exhibit self-healing characteristics.					
36446507	0	34	theme	framework	60:68	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	3	35	theme	bond	551:554	arg1	exchange					556:563	bond exchange	551:563	bond exchange	551:563	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	6	36	theme	mixed-dye	1074:1082	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	5	37	dep	type	912:915	arg1	the					908:910	the	908:910	the	908:910	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	5	38	theme	cross-linkers	949:961	arg1	composition					921:931	composition	921:931	composition	921:931	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	5	38	theme	cross-linkers	949:961	arg1	type					912:915	type	912:915	type	912:915	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	0	39	theme	covalent	51:58	arg1	materials					70:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials	0:78	Catalyst-free pH-responsive chitosan-based dynamic covalent framework materials.					
36446507	1	40	theme	moderate	324:331	arg1	conditions					333:342	moderate conditions	324:342	moderate conditions	324:342	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	5	41	theme	structural	811:820	arg1	properties					822:831	The structural properties	807:831	The structural properties of the synthesized dynamic covalent framework materials	807:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	2	42	theme	cross-linking	454:466	arg1	reactions					468:476	tripodal cross-linking reactions	445:476	tripodal cross-linking reactions without the need of any catalyst	445:509	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	6	43	theme	selective	1064:1072	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	3	44	theme	covalent	635:642	arg1	networks					644:651	their dynamic covalent networks	621:651	their dynamic covalent networks	621:651	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	1	45	theme	dynamic	134:140	arg1	materials					161:169	chitosan-based dynamic covalent framework materials	119:169	chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	119:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	2	46	theme	functional	410:419	arg1	groups					421:426	residual carboxylic acid functional groups	385:426	residual carboxylic acid functional groups	385:426	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36446507	1	47	theme	covalent	142:149	arg1	materials					161:169	chitosan-based dynamic covalent framework materials	119:169	chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	119:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	6	48	theme	pH-responsive	1045:1057	arg1	materials					1094:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials	1016:1102	This study showcased a novel approach to synthesize biodegradable, self-healing, pH-responsive, and selective mixed-dye adsorbent materials using chitosan as the building block.					
36446507	1	49	theme	framework	151:159	arg1	materials					161:169	chitosan-based dynamic covalent framework materials	119:169	chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	119:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	50	theme	materials	161:169	arg1	unit					313:316	the linker unit	302:316	the linker unit	302:316	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	50	theme	materials	161:169	arg1	example					108:114	a first example	100:114	a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA)	100:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	5	51	theme	dynamic	852:858	arg1	materials					879:887	the synthesized dynamic covalent framework materials	836:887	the synthesized dynamic covalent framework materials	836:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	3	52	theme	obtained	516:523	arg1	capable					540:546	capable	540:546	capable	540:546	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	3	52	theme	obtained	516:523	arg1	materials					525:533	The obtained materials	512:533	The obtained materials	512:533	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	3	53	theme	neighboring	569:579	arg1	effect					607:612	neighboring group participation (NGP) effect	569:612	neighboring group participation (NGP) effect	569:612	The obtained materials were capable of bond exchange via neighboring group participation (NGP) effect within their dynamic covalent networks.					
36446507	1	54	theme	trimesic	279:286	arg1	TMA					294:296	TMA	294:296	TMA	294:296	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	1	54	theme	trimesic	279:286	arg1	acid					288:291	trimesic acid	279:291	trimesic acid (TMA)	279:297	This study reports a first example of chitosan-based dynamic covalent framework materials successfully prepared through one-pot/ultrasonic-assisted amidation reaction via either citric acid (CA) or trimesic acid (TMA) as the linker unit under moderate conditions.					
36446507	5	55	theme	covalent	860:867	arg1	materials					879:887	the synthesized dynamic covalent framework materials	836:887	the synthesized dynamic covalent framework materials	836:887	The structural properties of the synthesized dynamic covalent framework materials were controlled by the type and composition of the tripodal cross-linkers.					
36446507	4	56	theme	framework	698:706	arg1	materials					708:716	the chitosan-based framework materials	679:716	the chitosan-based framework materials	679:716	It was demonstrated that the chitosan-based framework materials could undergo a dynamic transamidation reaction to exhibit self-healing characteristics.					
36446507	2	57	theme	catalyst	502:509	arg1	need					490:493	the need	486:493	the need of any catalyst	486:509	Chitosan-based framework materials with residual carboxylic acid functional groups were obtained by tripodal cross-linking reactions without the need of any catalyst.					
36209863	7	0	theme	DFT	1111:1113	arg1	calculations					1115:1126	DFT calculations	1111:1126	DFT calculations	1111:1126	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	2	1	theme	DFT	409:411	arg1	calculations					414:425	density functional theory (DFT) calculations	382:425	density functional theory (DFT) calculations	382:425	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	5	2	theme	air-water	797:805	arg1	interface					807:815	air-water interface	797:815	air-water interface	797:815	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	0	3	theme	nanobubbles	92:102	arg1	Role					84:87	Role	84:87	Role of nanobubbles	84:102	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	0	4	from	Adsorption	0:9	arg1	carbon					57:62	granular activated carbon	38:62	granular activated carbon	38:62	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	7	5	with	PFAAs	1043:1047	arg1	chains					1066:1071	shorter C-F chains	1054:1071	shorter C-F chains	1054:1071	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	0	6	dep	supported	64:72	arg1	Role					84:87	Role	84:87	Role of nanobubbles	84:102	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	5	7	from	groups	777:782	arg1	CS					791:792	CS	791:792	CS	791:792	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	5	7	from	groups	777:782	arg1	interface					807:815	air-water interface	797:815	air-water interface	797:815	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	5	8	with	PFAAs	712:716	arg1	chains					734:739	longer C-F chains	723:739	longer C-F chains	723:739	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	6	9	dep	form	910:913	arg1	solution					898:905	solution	898:905	solution	898:905	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
36209863	6	10	from	groups	980:985	arg1	CS					990:991	CS	990:991	CS through electrostatic interactions	990:1026	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
36209863	4	11	theme	surface	682:688	arg1	differences					699:709	surface activity differences	682:709	surface activity differences	682:709	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	0	12	theme	activated	47:55	arg1	carbon					57:62	granular activated carbon	38:62	granular activated carbon	38:62	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	7	13	theme	shorter	1054:1060	arg1	chains					1066:1071	shorter C-F chains	1054:1071	shorter C-F chains	1054:1071	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	8	14	attach	derived	1312:1318	arg1	groups					1355:1360	the abundant protonated amino groups	1325:1360	the abundant protonated amino groups	1325:1360	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	8	14	attach	derived	1312:1318	arg2	interactions					1267:1278	the electrostatic interactions	1249:1278	the electrostatic interactions between CS and PFAAs	1249:1299	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	5	15	theme	amino	771:775	arg1	groups					777:782	amino groups	771:782	amino groups on the CS or air-water interface on composite adsorbents	771:839	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	8	16	theme	abundant	1329:1336	arg1	groups					1355:1360	the abundant protonated amino groups	1325:1360	the abundant protonated amino groups	1325:1360	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	6	17	theme	amino	974:978	arg1	groups					980:985	protonated amino groups	963:985	protonated amino groups on CS through electrostatic interactions	963:1026	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
36209863	5	18	theme	longer	723:728	arg1	chains					734:739	longer C-F chains	723:739	longer C-F chains	723:739	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	3	19	theme	composite	476:484	arg1	CS/GAC					497:502	the composite adsorbent (CS/GAC)	472:503	the composite adsorbent (CS/GAC)	472:503	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	6	20	theme	protonated	963:972	arg1	groups					980:985	protonated amino groups	963:985	protonated amino groups on CS through electrostatic interactions	963:1026	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
36209863	0	21	theme	acids	29:33	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of perfluoroalkyl acids on granular activated carbon	0:62	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	2	22	theme	activated	252:260	arg1	GAC					270:272	GAC	270:272	GAC	270:272	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	22	theme	activated	252:260	arg1	carbon					262:267	granular activated carbon	243:267	granular activated carbon (GAC)	243:273	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	23	theme	adsorption	339:348	arg1	process					350:356	the adsorption process	335:356	the adsorption process	335:356	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	0	24	theme	perfluoroalkyl	14:27	arg1	acids					29:33	perfluoroalkyl acids	14:33	perfluoroalkyl acids	14:33	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	4	25	with	PFAAs	601:605	arg1	lengths					628:634	different chain lengths	612:634	different chain lengths	612:634	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	3	26	theme	acid	552:555	arg1	rate					526:529	the removal rate	514:529	the removal rate of perfluorooctanoic acid	514:555	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	2	27	theme	granular	243:250	arg1	GAC					270:272	GAC	270:272	GAC	270:272	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	27	theme	granular	243:250	arg1	carbon					262:267	granular activated carbon	243:267	granular activated carbon (GAC)	243:273	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	28	from	chitosan	226:233	arg1	GAC					270:272	GAC	270:272	GAC	270:272	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	28	from	chitosan	226:233	arg1	carbon					262:267	granular activated carbon	243:267	granular activated carbon (GAC)	243:273	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	0	29	theme	granular	38:45	arg1	carbon					57:62	granular activated carbon	38:62	granular activated carbon	38:62	Adsorption of perfluoroalkyl acids on granular activated carbon supported chitosan: Role of nanobubbles.					
36209863	4	30	contain	have	636:639	arg2	mechanisms					662:671	different adsorption mechanisms	641:671	different adsorption mechanisms owing to surface activity differences	641:709	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	4	30	contain	have	636:639	arg1	PFAAs					601:605	PFAAs	601:605	PFAAs with different chain lengths	601:634	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	3	31	theme	CS/GAC	497:502	arg1	use					465:467	the use	461:467	the use of the composite adsorbent (CS/GAC)	461:503	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	1	32	theme	growing	184:190	arg1	threat					116:121	The safety threat	105:121	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water	105:177	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	1	32	theme	growing	184:190	arg1	concern					192:198	a growing concern	182:198	a growing concern	182:198	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	2	33	theme	theory	401:406	arg1	calculations					414:425	density functional theory (DFT) calculations	382:425	density functional theory (DFT) calculations	382:425	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	7	34	theme	C-F	1062:1064	arg1	chains					1066:1071	shorter C-F chains	1054:1071	shorter C-F chains	1054:1071	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	5	35	theme	C-F	730:732	arg1	chains					734:739	longer C-F chains	723:739	longer C-F chains	723:739	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	2	36	theme	nanobubbles	320:330	arg1	role					312:315	the role	308:315	the role of nanobubbles in the adsorption process	308:356	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	2	37	theme	functional	390:399	arg1	calculations					414:425	density functional theory (DFT) calculations	382:425	density functional theory (DFT) calculations	382:425	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	8	38	theme	electrostatic	1253:1265	arg1	interactions					1267:1278	the electrostatic interactions	1249:1278	the electrostatic interactions between CS and PFAAs	1249:1299	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	3	39	theme	perfluorooctanoic	534:550	arg1	acid					552:555	perfluorooctanoic acid	534:555	perfluorooctanoic acid	534:555	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	3	40	theme	adsorbent	486:494	arg1	CS/GAC					497:502	the composite adsorbent (CS/GAC)	472:503	the composite adsorbent (CS/GAC)	472:503	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	1	41	theme	safety	109:114	arg1	threat					116:121	The safety threat	105:121	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water	105:177	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	1	41	theme	safety	109:114	arg1	concern					192:198	a growing concern	182:198	a growing concern	182:198	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	2	42	theme	density	382:388	arg1	calculations					414:425	density functional theory (DFT) calculations	382:425	density functional theory (DFT) calculations	382:425	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	7	43	theme	short-chain	1161:1171	arg1	PFAAs					1173:1177	short-chain PFAAs	1161:1177	short-chain PFAAs	1161:1177	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	8	44	theme	protonated	1338:1347	arg1	groups					1355:1360	the abundant protonated amino groups	1325:1360	the abundant protonated amino groups	1325:1360	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	3	45	theme	removal	518:524	arg1	rate					526:529	the removal rate	514:529	the removal rate of perfluorooctanoic acid	514:555	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	2	46	from	role	312:315	arg1	process					350:356	the adsorption process	335:356	the adsorption process	335:356	In this study, we loaded chitosan (CS) on granular activated carbon (GAC) to adsorb PFAAs, and we explored the role of nanobubbles in the adsorption process through experiments and density functional theory (DFT) calculations.					
36209863	4	47	theme	chain	622:626	arg1	lengths					628:634	different chain lengths	612:634	different chain lengths	612:634	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	4	48	theme	adsorption	651:660	arg1	mechanisms					662:671	different adsorption mechanisms	641:671	different adsorption mechanisms owing to surface activity differences	641:709	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	4	49	theme	activity	690:697	arg1	differences					699:709	surface activity differences	682:709	surface activity differences	682:709	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	4	50	theme	different	641:649	arg1	mechanisms					662:671	different adsorption mechanisms	641:671	different adsorption mechanisms owing to surface activity differences	641:709	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	4	51	theme	different	612:620	arg1	lengths					628:634	different chain lengths	612:634	different chain lengths	612:634	PFAAs with different chain lengths have different adsorption mechanisms owing to surface activity differences.					
36209863	5	52	theme	composite	820:828	arg1	adsorbents					830:839	composite adsorbents	820:839	composite adsorbents	820:839	PFAAs with longer C-F chains can be directly enriched with amino groups on the CS or air-water interface on composite adsorbents.					
36209863	7	53	theme	electrostatic	1201:1213	arg1	interactions					1215:1226	electrostatic interactions	1201:1226	electrostatic interactions	1201:1226	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	1	54	theme	Perfluoroalkyl	132:145	arg1	acids					147:151	Perfluoroalkyl acids	132:151	Perfluoroalkyl acids (PFAAs)	132:159	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	1	54	theme	Perfluoroalkyl	132:145	arg1	PFAAs					154:158	PFAAs	154:158	PFAAs	154:158	The safety threat posed by Perfluoroalkyl acids (PFAAs) in drinking water is a growing concern.					
36209863	6	55	theme	nanobubble-PFAA	915:929	arg1	colloids					931:938	nanobubble-PFAA colloids	915:938	nanobubble-PFAA colloids	915:938	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
36209863	3	56	theme	nanobubbles	588:598	arg1	assistance					574:583	the assistance	570:583	the assistance of nanobubbles	570:598	Compared with GAC, we found that the use of the composite adsorbent (CS/GAC) enhanced the removal rate of perfluorooctanoic acid by 136% with the assistance of nanobubbles.					
36209863	8	57	theme	amino	1349:1353	arg1	groups					1355:1360	the abundant protonated amino groups	1325:1360	the abundant protonated amino groups	1325:1360	We also proved that the electrostatic interactions between CS and PFAAs are mainly derived from the abundant protonated amino groups.					
36209863	7	58	theme	PFAAs	1173:1177	arg1	adsorption					1147:1156	the adsorption	1143:1156	the adsorption of short-chain PFAAs	1143:1177	We found that PFAAs with shorter C-F chains are less affected by nanobubbles, and DFT calculations indicated that the adsorption of short-chain PFAAs is mainly affected by electrostatic interactions.					
36209863	6	59	theme	electrostatic	1001:1013	arg1	interactions					1015:1026	electrostatic interactions	1001:1026	electrostatic interactions	1001:1026	Additionally, PFAAs can be enriched with nanobubbles in solution to form nanobubble-PFAA colloids, which are adsorbed by protonated amino groups on CS through electrostatic interactions.					
37220975	1	0	theme	biochemical	275:285	arg1	characteristics					287:301	physiological biochemical characteristics	261:301	physiological biochemical characteristics	261:301	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	10	1	theme	VOC	2172:2174	arg1	composition					2176:2186	the changed VOC composition	2160:2186	the changed VOC composition	2160:2186	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	3	2	theme	Isochrysis	731:740	arg1	galbana					742:748	high quality microalgal food Isochrysis galbana	702:748	high quality microalgal food Isochrysis galbana	702:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	12	3	theme	biochemical	2529:2539	arg1	metabolism					2541:2550	biochemical metabolism	2529:2550	biochemical metabolism	2529:2550	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	13	4	theme	multiple	2753:2760	arg1	bioactivities					2762:2774	multiple bioactivities	2753:2774	multiple bioactivities	2753:2774	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	10	5	theme	acids	2208:2212	arg1	degradation					2218:2228	degradation	2218:2228	degradation of free amino acids	2218:2248	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	10	5	theme	acids	2208:2212	arg1	oxidation					2189:2197	oxidation	2189:2197	oxidation of fatty acids	2189:2212	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	3	6	theme	microalgal	715:724	arg1	galbana					742:748	high quality microalgal food Isochrysis galbana	702:748	high quality microalgal food Isochrysis galbana	702:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	9	7	theme	high	2080:2083	arg1	density					2085:2091	high density	2080:2091	high density of KV	2080:2097	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	8	8	theme	global	1815:1820	arg1	composition					1822:1832	The global composition	1811:1832	The global composition of FAs	1811:1839	The global composition of FAs did not significantly vary among the groups.					
37220975	10	9	theme	free	2233:2236	arg1	acids					2244:2248	free amino acids	2233:2248	free amino acids	2233:2248	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	7	10	theme	galbana	1678:1684	arg1	control					1686:1692	the pure I. galbana control	1666:1692	the pure I. galbana control	1666:1692	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	4	11	theme	clam	1052:1055	arg1	rate					1040:1043	The survival rate	1027:1043	The survival rate of the clam	1027:1055	The survival rate of the clam showed dinoflagellate density and species specificity.					
37220975	12	12	theme	seafood	2556:2562	arg1	qulity					2564:2569	seafood qulity	2556:2569	seafood qulity	2556:2569	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	6	13	theme	protein	1435:1441	arg1	metabolism					1443:1452	protein metabolism	1435:1452	protein metabolism	1435:1452	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	11	14	theme	flavor	2423:2428	arg1	quality					2430:2436	food flavor quality	2418:2436	food flavor quality	2418:2436	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	4	15	theme	dinoflagellate	1064:1077	arg1	density					1079:1085	dinoflagellate density	1064:1085	dinoflagellate density	1064:1085	The survival rate of the clam showed dinoflagellate density and species specificity.					
37220975	0	16	theme	dinoflagellate	125:138	arg1	species					140:146	the dinoflagellate species	121:146	the dinoflagellate species Karlodinium veneficum and K. zhouanum	121:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	0	16	theme	dinoflagellate	125:138	arg1	Karlodinium					148:158	Karlodinium	148:158	Karlodinium	148:158	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	0	16	theme	dinoflagellate	125:138	arg1	K.					174:175	K.	174:175	K.	174:175	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	7	17	located	present	1631:1637	arg1	samples					1652:1658	the field samples	1642:1658	the field samples	1642:1658	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	17	located	present	1631:1637	arg2	it					1620:1621	it	1620:1621	it	1620:1621	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	1	18	theme	bivalves	321:328	arg1	growth					250:255	growth	250:255	growth	250:255	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	1	18	theme	bivalves	321:328	arg1	characteristics					287:301	physiological biochemical characteristics	261:301	physiological biochemical characteristics	261:301	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	12	19	theme	clam	2578:2581	arg1	metabolism					2541:2550	biochemical metabolism	2529:2550	biochemical metabolism	2529:2550	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	12	19	theme	clam	2578:2581	arg1	qulity					2564:2569	seafood qulity	2556:2569	seafood qulity	2556:2569	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	13	20	with	KZ	2607:2608	arg1	density					2624:2630	moderate density	2615:2630	moderate density	2615:2630	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	3	21	theme	manila	773:778	arg1	clam					780:783	feeding manila clam	765:783	feeding manila clam	765:783	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	22	theme	species	635:641	arg1	densities					606:614	Different densities	596:614	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana	596:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	13	23	theme	high-valued	2726:2736	arg1	carnosine					2713:2721	carnosine	2713:2721	carnosine	2713:2721	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	13	23	theme	high-valued	2726:2736	arg1	substance					2738:2746	a high-valued substance	2724:2746	a high-valued substance with multiple bioactivities	2724:2774	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	7	24	theme	weight	1553:1558	arg1	84.74 ± 8.59 μg/g					1521:1537	84.74 ± 8.59 μg/g	1521:1537	84.74 ± 8.59 μg/g of muscle wet weight	1521:1558	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	10	25	theme	acids	2244:2248	arg1	degradation					2218:2228	degradation	2218:2228	degradation of free amino acids	2218:2248	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	10	25	theme	acids	2244:2248	arg1	oxidation					2189:2197	oxidation	2189:2197	oxidation of fatty acids	2189:2212	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	3	26	theme	14-day	814:819	arg1	culture					831:837	a 14-day temporary culture	812:837	a 14-day temporary culture	812:837	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	0	27	dep	Karlodinium	148:158	arg1	veneficum					160:168	Karlodinium veneficum	148:168	Karlodinium veneficum	148:168	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	7	28	theme	muscle	1542:1547	arg1	weight					1553:1558	muscle wet weight	1542:1558	muscle wet weight	1542:1558	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	29	theme	pure	1670:1673	arg1	control					1686:1692	the pure I. galbana control	1666:1692	the pure I. galbana control	1666:1692	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	6	30	theme	glycogen	1360:1367	arg1	contents					1377:1384	the glycogen and FAA contents	1356:1384	the glycogen and FAA contents	1356:1384	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	9	31	theme	fatty	2127:2131	arg1	acids					2133:2137	fatty acids	2127:2137	fatty acids	2127:2137	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	7	32	theme	field	1646:1650	arg1	samples					1652:1658	the field samples	1642:1658	the field samples	1642:1658	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	9	33	theme	endogenous	1911:1920	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	33	theme	endogenous	1911:1920	arg1	acid					1951:1954	linoleic acid	1942:1954	linoleic acid	1942:1954	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	33	theme	endogenous	1911:1920	arg1	acid					1972:1975	α-linolenic acid	1960:1975	α-linolenic acid	1960:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	3	34	theme	biochemical	880:890	arg1	metabolites					892:902	the critical biochemical metabolites	867:902	the critical biochemical metabolites	867:902	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	34	theme	biochemical	880:890	arg1	glycogen					912:919	glycogen	912:919	glycogen	912:919	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	34	theme	biochemical	880:890	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	0	35	from	Changes	0:6	arg1	metabolites					23:33	biochemical metabolites	11:33	biochemical metabolites in manila clam	11:48	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	3	36	theme	organic	975:981	arg1	VOCs					994:997	VOCs	994:997	VOCs	994:997	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	36	theme	organic	975:981	arg1	compounds					983:991	volatile organic compounds	966:991	volatile organic compounds (VOCs)	966:998	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	36	theme	organic	975:981	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	0	37	theme	high-quality	81:92	arg1	feed					105:108	high-quality microalgal feed	81:108	high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum	81:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	3	38	theme	free	922:925	arg1	FAAs					940:943	FAAs	940:943	FAAs	940:943	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	38	theme	free	922:925	arg1	glycogen					912:919	glycogen	912:919	glycogen	912:919	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	38	theme	free	922:925	arg1	acids					953:957	fatty acids	947:957	fatty acids (FAs)	947:963	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	38	theme	free	922:925	arg1	metabolites					892:902	the critical biochemical metabolites	867:902	the critical biochemical metabolites	867:902	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	38	theme	free	922:925	arg1	compounds					983:991	volatile organic compounds	966:991	volatile organic compounds (VOCs)	966:998	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	38	theme	free	922:925	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	7	39	theme	carnosine	1493:1501	arg1	carnosine					1493:1501	carnosine	1493:1501	carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight)	1493:1559	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	39	theme	carnosine	1493:1501	arg1	Amount					1483:1488	Amount	1483:1488	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight)	1483:1559	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	9	40	theme	linoleic	1942:1949	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	40	theme	linoleic	1942:1949	arg1	acid					1951:1954	linoleic acid	1942:1954	linoleic acid	1942:1954	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	41	theme	acids	2133:2137	arg1	metabolisms					2112:2122	the metabolisms	2108:2122	the metabolisms of fatty acids	2108:2137	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	11	42	theme	more	2389:2392	arg1	taste					2400:2404	a more fishy taste	2387:2404	a more fishy taste	2387:2404	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	0	43	theme	temporary	58:66	arg1	culture					68:74	a temporary culture	56:74	a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum	56:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	6	44	theme	FAA	1373:1375	arg1	contents					1377:1384	the glycogen and FAA contents	1356:1384	the glycogen and FAA contents	1356:1384	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	1	45	theme	filter-feeding	306:319	arg1	bivalves					321:328	filter-feeding bivalves	306:328	filter-feeding bivalves	306:328	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	2	46	theme	mariculture	477:487	arg1	organism					489:496	the mariculture organism	473:496	the mariculture organism	473:496	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	0	47	theme	biochemical	11:21	arg1	metabolites					23:33	biochemical metabolites	11:33	biochemical metabolites in manila clam	11:48	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	7	48	located	detected	1565:1572	arg2	Amount					1483:1488	Amount	1483:1488	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight)	1483:1559	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	48	located	detected	1565:1572	arg1	groups					1606:1611	all the dinoflagellate-mixed groups	1577:1611	all the dinoflagellate-mixed groups	1577:1611	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	48	located	detected	1565:1572	arg2	carnosine					1493:1501	carnosine	1493:1501	carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight)	1493:1559	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	49	theme	dinoflagellate-mixed	1585:1604	arg1	groups					1606:1611	all the dinoflagellate-mixed groups	1577:1611	all the dinoflagellate-mixed groups	1577:1611	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	2	50	theme	seafood	454:460	arg1	quality					462:468	seafood quality	454:468	seafood quality of the mariculture organism	454:496	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	7	51	attach	present	1631:1637	arg1	control					1686:1692	the pure I. galbana control	1666:1692	the pure I. galbana control	1666:1692	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	51	attach	present	1631:1637	arg1	samples					1652:1658	the field samples	1642:1658	the field samples	1642:1658	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	51	attach	present	1631:1637	arg2	it					1620:1621	it	1620:1621	it	1620:1621	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	6	52	theme	KV	1346:1347	arg1	group					1349:1353	the high-density KV group	1329:1353	the high-density KV group	1329:1353	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	5	53	theme	KV	1129:1130	arg1	group					1132:1136	The high-density KV group	1112:1136	The high-density KV group	1112:1136	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	13	54	from	beneficial	2657:2666	arg1	aquaculture					2671:2681	aquaculture	2671:2681	aquaculture	2671:2681	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	9	55	theme	KV	2021:2022	arg1	group					2024:2028	the high-density KV group	2004:2028	the high-density KV group	2004:2028	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	13	56	from	KZ	2607:2608	arg1	feed					2639:2642	the feed	2635:2642	the feed	2635:2642	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	7	57	theme	anti-stress	1738:1748	arg1	activities					1750:1759	the anti-stress activities	1734:1759	the anti-stress activities when the clam was exposed to the dinoflagellates	1734:1808	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	3	58	dep	K.	673:674	arg1	zhouanum					676:683	K. zhouanum	673:683	K. zhouanum (KZ)	673:688	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	59	theme	quality	707:713	arg1	galbana					742:748	high quality microalgal food Isochrysis galbana	702:748	high quality microalgal food Isochrysis galbana	702:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	2	60	theme	mariculture	397:407	arg1	areas					409:413	mariculture areas	397:413	mariculture areas	397:413	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	1	61	theme	physiological	261:273	arg1	characteristics					287:301	physiological biochemical characteristics	261:301	physiological biochemical characteristics	261:301	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	10	62	theme	composition	2176:2186	arg1	results					2149:2155	the results	2145:2155	the results of the changed VOC composition	2145:2186	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	2	63	from	biomass	375:381	arg1	areas					409:413	mariculture areas	397:413	mariculture areas	397:413	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	13	64	from	aquaculture	2671:2681	arg1	beneficial					2657:2666	beneficial	2657:2666	beneficial	2657:2666	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	9	65	theme	other	2050:2054	arg1	groups					2056:2061	the other groups	2046:2061	all the other groups	2042:2061	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	0	66	with	culture	68:74	arg1	feed					105:108	high-quality microalgal feed	81:108	high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum	81:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	13	67	theme	moderate	2615:2622	arg1	density					2624:2630	moderate density	2615:2630	moderate density	2615:2630	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	10	68	theme	changed	2164:2170	arg1	composition					2176:2186	the changed VOC composition	2160:2186	the changed VOC composition	2160:2186	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	2	69	from	blooms	387:392	arg1	areas					409:413	mariculture areas	397:413	mariculture areas	397:413	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	3	70	from	metabolites	892:902	arg1	clam					1007:1010	the clam	1003:1010	the clam	1003:1010	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	4	71	theme	species	1091:1097	arg1	specificity					1099:1109	species specificity	1091:1109	species specificity	1091:1109	The survival rate of the clam showed dinoflagellate density and species specificity.					
37220975	2	72	dep	understood	584:593	arg1	affected					502:509	affected	502:509	are affected by the dinoflagellates, especially those at nonfatal levels	498:569	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	10	73	theme	fatty	2202:2206	arg1	acids					2208:2212	fatty acids	2202:2212	fatty acids	2202:2212	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	7	74	from	samples	1652:1658	arg1	present					1631:1637	present	1631:1637	present	1631:1637	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	3	75	theme	food	726:729	arg1	galbana					742:748	high quality microalgal food Isochrysis galbana	702:748	high quality microalgal food Isochrysis galbana	702:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	1	76	theme	Phytoplankton	187:199	arg1	composition					201:211	Phytoplankton composition	187:211	Phytoplankton composition	187:211	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	1	76	theme	Phytoplankton	187:199	arg1	factor					229:234	an important factor	216:234	an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves	216:328	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	7	77	theme	I.	1675:1676	arg1	control					1686:1692	the pure I. galbana control	1666:1692	the pure I. galbana control	1666:1692	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	3	78	theme	feeding	765:771	arg1	clam					780:783	feeding manila clam	765:783	feeding manila clam	765:783	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	8	79	theme	FAs	1837:1839	arg1	composition					1822:1832	The global composition	1811:1832	The global composition of FAs	1811:1839	The global composition of FAs did not significantly vary among the groups.					
37220975	3	80	theme	Different	596:604	arg1	densities					606:614	Different densities	596:614	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana	596:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	81	dep	K.	651:652	arg1	veneficum					654:662	K. veneficum (KV)	651:667	K. veneficum (KV)	651:667	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	1	82	dep	growth	250:255	arg1	the					246:248	the	246:248	the	246:248	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	9	83	theme	KV	2096:2097	arg1	density					2085:2091	high density	2080:2091	high density of KV	2080:2097	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	1	84	theme	important	219:227	arg1	composition					201:211	Phytoplankton composition	187:211	Phytoplankton composition	187:211	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	1	84	theme	important	219:227	arg1	factor					229:234	an important factor	216:234	an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves	216:328	Phytoplankton composition is an important factor affecting the growth and physiological biochemical characteristics of filter-feeding bivalves.					
37220975	13	85	with	substance	2738:2746	arg1	bioactivities					2762:2774	multiple bioactivities	2753:2774	multiple bioactivities	2753:2774	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	3	86	theme	Karlodinium	623:633	arg1	K.					673:674	K.	673:674	K.	673:674	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	86	theme	Karlodinium	623:633	arg1	species					635:641	two Karlodinium species	619:641	two Karlodinium species	619:641	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	86	theme	Karlodinium	623:633	arg1	K.					651:652	K.	651:652	K.	651:652	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	0	87	dep	K.	174:175	arg1	zhouanum					177:184	K. zhouanum	174:184	K. zhouanum	174:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	7	88	theme	wet	1549:1551	arg1	weight					1553:1558	muscle wet weight	1542:1558	muscle wet weight	1542:1558	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	5	89	from	concentrations	1242:1255	arg1	KZ					1232:1233	KZ	1232:1233	KZ at low concentrations	1232:1255	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	11	90	theme	increased	2307:2315	arg1	aldehydes					2331:2339	aldehydes	2331:2339	aldehydes	2331:2339	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	11	90	theme	increased	2307:2315	arg1	VOCs					2317:2320	The increased VOCs	2303:2320	The increased VOCs	2303:2320	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	7	91	dep	carnosine	1493:1501	arg1	49.91 ± 14.64					1504:1516	49.91 ± 14.64	1504:1516	49.91 ± 14.64	1504:1516	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	9	92	theme	PUFA	1926:1929	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	92	theme	PUFA	1926:1929	arg1	acid					1951:1954	linoleic acid	1942:1954	linoleic acid	1942:1954	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	92	theme	PUFA	1926:1929	arg1	acid					1972:1975	α-linolenic acid	1960:1975	α-linolenic acid	1960:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	2	93	theme	increasing	340:349	arg1	trend					351:355	the increasing trend	336:355	the increasing trend in dinoflagellate biomass and blooms in mariculture areas	336:413	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	10	94	theme	amino	2238:2242	arg1	acids					2244:2248	free amino acids	2233:2248	free amino acids	2233:2248	From the results of the changed VOC composition, oxidation of fatty acids and degradation of free amino acids might occur in the clams exposed to dinoflagellates.					
37220975	5	95	dep	%	1162:1162	arg1	to					1157:1158	to	1157:1158	to	1157:1158	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	3	96	theme	temporary	821:829	arg1	culture					831:837	a 14-day temporary culture	812:837	a 14-day temporary culture	812:837	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	6	97	theme	high-density	1333:1344	arg1	group					1349:1353	the high-density KV group	1329:1353	the high-density KV group	1329:1353	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	0	98	dep	species	140:146	arg1	species					140:146	the dinoflagellate species	121:146	the dinoflagellate species Karlodinium veneficum and K. zhouanum	121:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	0	98	dep	species	140:146	arg1	Karlodinium					148:158	Karlodinium	148:158	Karlodinium	148:158	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	0	98	dep	species	140:146	arg1	K.					174:175	K.	174:175	K.	174:175	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	0	99	from	metabolites	23:33	arg1	clam					45:48	manila clam	38:48	manila clam	38:48	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	7	100	from	present	1631:1637	arg1	control					1686:1692	the pure I. galbana control	1666:1692	the pure I. galbana control	1666:1692	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	7	100	from	present	1631:1637	arg1	samples					1652:1658	the field samples	1642:1658	the field samples	1642:1658	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	5	101	theme	galbana	1195:1201	arg1	control					1203:1209	the pure I. galbana control	1183:1209	the pure I. galbana control	1183:1209	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	13	102	theme	carnosine	2713:2721	arg1	content					2702:2708	the content	2698:2708	the content of carnosine, a high-valued substance with multiple bioactivities	2698:2774	However, KZ with moderate density in the feed seemed to be beneficial in aquaculture for increasing the content of carnosine, a high-valued substance with multiple bioactivities.					
37220975	11	103	theme	decreased	2346:2354	arg1	1-octen-3-ol					2356:2367	decreased 1-octen-3-ol	2346:2367	decreased 1-octen-3-ol	2346:2367	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	9	104	theme	C18	1922:1924	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	104	theme	C18	1922:1924	arg1	acid					1951:1954	linoleic acid	1942:1954	linoleic acid	1942:1954	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	104	theme	C18	1922:1924	arg1	acid					1972:1975	α-linolenic acid	1960:1975	α-linolenic acid	1960:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	11	105	theme	food	2418:2421	arg1	quality					2430:2436	food flavor quality	2418:2436	food flavor quality	2418:2436	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	0	106	theme	microalgal	94:103	arg1	feed					105:108	high-quality microalgal feed	81:108	high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum	81:184	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	12	107	theme	present	2493:2499	arg1	study					2501:2505	This present study	2488:2505	This present study	2488:2505	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	2	108	from	trend	351:355	arg1	blooms					387:392	blooms	387:392	blooms	387:392	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	2	108	from	trend	351:355	arg1	biomass					375:381	dinoflagellate biomass	360:381	dinoflagellate biomass	360:381	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	11	109	theme	fishy	2394:2398	arg1	taste					2400:2404	a more fishy taste	2387:2404	a more fishy taste	2387:2404	The increased VOCs, such as aldehydes, and decreased 1-octen-3-ol probably produced a more fishy taste and reduced food flavor quality when the clam was exposed to the dinoflagellates.					
37220975	9	110	theme	precursors	1931:1940	arg1	contents					1895:1902	contents	1895:1902	contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1895:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	12	111	dep	metabolism	2541:2550	arg1	the					2525:2527	the	2525:2527	the	2525:2527	This present study demonstrated that the biochemical metabolism and seafood qulity of the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	FAAs					940:943	FAAs	940:943	FAAs	940:943	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	glycogen					912:919	glycogen	912:919	glycogen	912:919	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	acids					953:957	fatty acids	947:957	fatty acids (FAs)	947:963	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	metabolites					892:902	the critical biochemical metabolites	867:902	the critical biochemical metabolites	867:902	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	compounds					983:991	volatile organic compounds	966:991	volatile organic compounds (VOCs)	966:998	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	112	theme	amino	927:931	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	2	113	theme	nonfatal	555:562	arg1	levels					564:569	nonfatal levels	555:569	nonfatal levels	555:569	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	2	114	theme	physio-biochemical	424:441	arg1	traits					443:448	the physio-biochemical traits	420:448	the physio-biochemical traits	420:448	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	2	115	theme	organism	489:496	arg1	traits					443:448	the physio-biochemical traits	420:448	the physio-biochemical traits	420:448	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	2	115	theme	organism	489:496	arg1	quality					462:468	seafood quality	454:468	seafood quality of the mariculture organism	454:496	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	9	116	theme	α-linolenic	1960:1970	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	116	theme	α-linolenic	1960:1970	arg1	acid					1972:1975	α-linolenic acid	1960:1975	α-linolenic acid	1960:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	5	117	theme	low	1238:1240	arg1	concentrations					1242:1255	low concentrations	1238:1255	low concentrations	1238:1255	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	5	118	theme	survival	1148:1155	arg1	%					1162:1162	survival to 32%	1148:1162	survival to 32%	1148:1162	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	0	119	theme	manila	38:43	arg1	clam					45:48	manila clam	38:48	manila clam	38:48	Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum.					
37220975	5	120	theme	pure	1187:1190	arg1	control					1203:1209	the pure I. galbana control	1183:1209	the pure I. galbana control	1183:1209	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	5	121	theme	high-density	1116:1127	arg1	group					1132:1136	The high-density KV group	1112:1136	The high-density KV group	1112:1136	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	6	122	dep	decreased	1386:1394	arg1	p < 0.05					1397:1404	p < 0.05	1397:1404	p < 0.05	1397:1404	In the high-density KV group, the glycogen and FAA contents decreased (p < 0.05), indicating that energy and protein metabolism were significantly affected.					
37220975	9	123	theme	high-density	2008:2019	arg1	group					2024:2028	the high-density KV group	2004:2028	the high-density KV group	2004:2028	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	124	dep	precursors	1931:1940	arg1	precursors					1931:1940	the endogenous C18 PUFA precursors	1907:1940	the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid	1907:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	124	dep	precursors	1931:1940	arg1	acid					1951:1954	linoleic acid	1942:1954	linoleic acid	1942:1954	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	9	124	dep	precursors	1931:1940	arg1	acid					1972:1975	α-linolenic acid	1960:1975	α-linolenic acid	1960:1975	However, contents of the endogenous C18 PUFA precursors linoleic acid and α-linolenic acid significantly decreased in the high-density KV group compared to all the other groups, indicating that high density of KV affected the metabolisms of fatty acids.					
37220975	3	125	theme	fatty	947:951	arg1	acids					953:957	fatty acids	947:957	fatty acids (FAs)	947:963	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	125	theme	fatty	947:951	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	125	theme	fatty	947:951	arg1	FAs					960:962	FAs	960:962	FAs	960:962	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	7	126	from	control	1686:1692	arg1	present					1631:1637	present	1631:1637	present	1631:1637	Amount of carnosine (49.91 ± 14.64 to 84.74 ± 8.59 μg/g of muscle wet weight) was detected in all the dinoflagellate-mixed groups, while it was not present in the field samples or in the pure I. galbana control, showing that carnosine participated in the anti-stress activities when the clam was exposed to the dinoflagellates.					
37220975	4	127	theme	survival	1031:1038	arg1	rate					1040:1043	The survival rate	1027:1043	The survival rate of the clam	1027:1055	The survival rate of the clam showed dinoflagellate density and species specificity.					
37220975	2	128	theme	dinoflagellate	360:373	arg1	biomass					375:381	dinoflagellate biomass	360:381	dinoflagellate biomass	360:381	With the increasing trend in dinoflagellate biomass and blooms in mariculture areas, how the physio-biochemical traits and seafood quality of the mariculture organism are affected by the dinoflagellates, especially those at nonfatal levels, is not well understood.					
37220975	3	129	theme	volatile	966:973	arg1	VOCs					994:997	VOCs	994:997	VOCs	994:997	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	129	theme	volatile	966:973	arg1	compounds					983:991	volatile organic compounds	966:991	volatile organic compounds (VOCs)	966:998	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	129	theme	volatile	966:973	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	130	theme	high	702:705	arg1	galbana					742:748	high quality microalgal food Isochrysis galbana	702:748	high quality microalgal food Isochrysis galbana	702:748	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	5	131	theme	I.	1192:1193	arg1	control					1203:1209	the pure I. galbana control	1183:1209	the pure I. galbana control	1183:1209	The high-density KV group inhibited survival to 32% lower than that of the pure I. galbana control, respectively, while KZ at low concentrations did not significantly affect the survival compared with the control.					
37220975	3	132	theme	critical	871:878	arg1	metabolites					892:902	the critical biochemical metabolites	867:902	the critical biochemical metabolites	867:902	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	132	theme	critical	871:878	arg1	glycogen					912:919	glycogen	912:919	glycogen	912:919	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
37220975	3	132	theme	critical	871:878	arg1	acids					933:937	free amino acids	922:937	free amino acids (FAAs)	922:944	Different densities of two Karlodinium species, namely K. veneficum (KV) and K. zhouanum (KZ), mixed with high quality microalgal food Isochrysis galbana was applied in feeding manila clam Ruditapes philippinarum in a 14-day temporary culture, to comparatively study how the critical biochemical metabolites such as glycogen, free amino acids (FAAs), fatty acids (FAs), volatile organic compounds (VOCs) in the clam were affected.					
35421802	10	0	theme	great	1586:1590	arg1	promise					1592:1598	great promise	1586:1598	great promise for further cultivated meat research	1586:1635	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	10	1	contain	have	1581:1584	arg2	promise					1592:1598	great promise	1586:1598	great promise for further cultivated meat research	1586:1635	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	10	1	contain	have	1581:1584	arg1	findings					1572:1579	these findings	1566:1579	these findings	1566:1579	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	2	2	theme	scaffolding	369:379	arg1	compositions					381:392	two plant-protein-enriched scaffolding compositions	342:392	two plant-protein-enriched scaffolding compositions	342:392	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	2	theme	scaffolding	369:379	arg1	platforms					446:454	3D-printable platforms	433:454	3D-printable platforms for bovine satellite cells (BSC) maturation	433:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	7	3	theme	PPI-enriched	1232:1243	arg1	bioinks					1245:1251	PPI-enriched bioinks	1232:1251	PPI-enriched bioinks	1232:1251	Finally, cellular bioprinting was demonstrated with PPI-enriched bioinks.					
35421802	8	4	theme	Cell	1254:1257	arg1	post-printing					1268:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	2	5	theme	plant-protein-enriched	346:367	arg1	compositions					381:392	two plant-protein-enriched scaffolding compositions	342:392	two plant-protein-enriched scaffolding compositions	342:392	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	5	theme	plant-protein-enriched	346:367	arg1	platforms					446:454	3D-printable platforms	433:454	3D-printable platforms for bovine satellite cells (BSC) maturation	433:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	10	6	theme	further	1604:1610	arg1	research					1628:1635	further cultivated meat research	1604:1635	further cultivated meat research	1604:1635	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	6	7	theme	fabricated	1083:1092	arg1	constructs					1094:1103	Successfully fabricated constructs	1070:1103	Successfully fabricated constructs with well-defined geometries	1070:1132	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	8	8	located	observed	1286:1293	arg2	post-printing					1268:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	8	8	located	observed	1286:1293	arg1	configurations					1314:1327	two cultivation configurations	1298:1327	two cultivation configurations	1298:1327	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	10	9	theme	animal-derived	1439:1452	arg1	materials					1454:1462	animal-derived materials	1439:1462	animal-derived materials	1439:1462	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	3	10	theme	soy	543:545	arg1	SPI					564:566	SPI	564:566	SPI	564:566	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	10	theme	soy	543:545	arg1	isolate					555:561	soy protein isolate	543:561	soy protein isolate (SPI)	543:567	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	5	11	theme	Extrusion	944:952	arg1	3D-printing					960:970	Extrusion based 3D-printing	944:970	Extrusion based 3D-printing with the two compositions	944:996	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	3	12	theme	protein	547:553	arg1	SPI					564:566	SPI	564:566	SPI	564:566	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	12	theme	protein	547:553	arg1	isolate					555:561	soy protein isolate	543:561	soy protein isolate (SPI)	543:567	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	4	13	dep	BSC	914:916	arg1	spreading					918:926	spreading	918:926	spreading	918:926	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	1	14	theme	Cultivated	79:88	arg1	meat					90:93	Cultivated meat	79:93	Cultivated meat	79:93	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	2	15	theme	promising	282:290	arg1	method					292:297	a promising method	280:297	a promising method for creating thick and complex structures	280:339	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	15	theme	promising	282:290	arg1	3D-printing					265:275	3D-printing	265:275	3D-printing	265:275	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	9	16	theme	3D-printed	1404:1413	arg1	constructs					1424:1433	3D-printed cellular constructs	1404:1433	3D-printed cellular constructs	1404:1433	Moreover, cells could mature within 3D-printed cellular constructs.					
35421802	5	17	dep	edible	1033:1038	arg1	removable					1041:1049	removable	1041:1049	removable	1041:1049	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	10	18	theme	cultivated	1612:1621	arg1	research					1628:1635	further cultivated meat research	1604:1635	further cultivated meat research	1604:1635	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	10	19	theme	fabrication	1493:1503	arg1	process					1505:1511	our scaffold fabrication process	1480:1511	our scaffold fabrication process	1480:1511	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	2	20	theme	3D-printable	433:444	arg1	compositions					381:392	two plant-protein-enriched scaffolding compositions	342:392	two plant-protein-enriched scaffolding compositions	342:392	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	20	theme	3D-printable	433:444	arg1	platforms					446:454	3D-printable platforms	433:454	3D-printable platforms for bovine satellite cells (BSC) maturation	433:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	4	21	theme	Mold-based	761:770	arg1	scaffolds					789:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	5	22	with	3D-printing	960:970	arg1	compositions					985:996	the two compositions	977:996	the two compositions	977:996	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	3	23	with	Mixtures	501:508	arg1	alginate					587:594	RGD-modified alginate	574:594	RGD-modified alginate (Alginate(RGD))	574:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	0	24	theme	3D-printable	0:11	arg1	scaffolds					36:44	3D-printable plant protein-enriched scaffolds	0:44	3D-printable plant protein-enriched scaffolds for cultivated meat development	0:76	3D-printable plant protein-enriched scaffolds for cultivated meat development.					
35421802	9	25	theme	cellular	1415:1422	arg1	constructs					1424:1433	3D-printed cellular constructs	1404:1433	3D-printed cellular constructs	1404:1433	Moreover, cells could mature within 3D-printed cellular constructs.					
35421802	0	26	theme	plant	13:17	arg1	scaffolds					36:44	3D-printable plant protein-enriched scaffolds	0:44	3D-printable plant protein-enriched scaffolds for cultivated meat development	0:76	3D-printable plant protein-enriched scaffolds for cultivated meat development.					
35421802	6	27	with	constructs	1094:1103	arg1	geometries					1123:1132	well-defined geometries	1110:1132	well-defined geometries	1110:1132	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	10	28	theme	meat	1623:1626	arg1	research					1628:1635	further cultivated meat research	1604:1635	further cultivated meat research	1604:1635	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	10	29	theme	scaffold	1484:1491	arg1	process					1505:1511	our scaffold fabrication process	1480:1511	our scaffold fabrication process	1480:1511	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	1	30	theme	tissue	105:110	arg1	engineering					112:122	tissue engineering	105:122	tissue engineering (TE) concepts to create sustainable, edible muscle tissues	105:181	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	1	30	theme	tissue	105:110	arg1	TE					125:126	TE	125:126	TE	125:126	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	7	31	theme	cellular	1189:1196	arg1	bioprinting					1198:1208	cellular bioprinting	1189:1208	cellular bioprinting	1189:1208	Finally, cellular bioprinting was demonstrated with PPI-enriched bioinks.					
35421802	3	32	dep	alginate	587:594	arg1	RGD					606:608	RGD	606:608	RGD	606:608	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	32	dep	alginate	587:594	arg1	Alginate					597:604	Alginate	597:604	Alginate(RGD)	597:609	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	2	33	theme	satellite	467:475	arg1	BSC					484:486	BSC	484:486	BSC	484:486	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	33	theme	satellite	467:475	arg1	cells					477:481	bovine satellite cells	460:481	bovine satellite cells (BSC) maturation	460:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	34	theme	thick	312:316	arg1	structures					330:339	thick and complex structures	312:339	thick and complex structures	312:339	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	35	theme	bovine	460:465	arg1	BSC					484:486	BSC	484:486	BSC	484:486	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	2	35	theme	bovine	460:465	arg1	cells					477:481	bovine satellite cells	460:481	bovine satellite cells (BSC) maturation	460:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	10	36	link	animal-derived	1439:1452	arg1	materials					1454:1462	animal-derived materials	1439:1462	animal-derived materials	1439:1462	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	4	37	theme	unhindered	903:912	arg1	BSC					914:916	unhindered BSC spreading and maturation	903:941	BSC	914:916	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	1	38	dep	sustainable	148:158	arg1	edible					161:166	edible	161:166	edible	161:166	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	5	39	theme	based	954:958	arg1	3D-printing					960:970	Extrusion based 3D-printing	944:970	Extrusion based 3D-printing with the two compositions	944:996	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	0	40	theme	protein-enriched	19:34	arg1	scaffolds					36:44	3D-printable plant protein-enriched scaffolds	0:44	3D-printable plant protein-enriched scaffolds for cultivated meat development	0:76	3D-printable plant protein-enriched scaffolds for cultivated meat development.					
35421802	10	41	theme	low	1547:1549	arg1	risk					1560:1563	its low allergic risk	1543:1563	its low allergic risk	1543:1563	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	5	42	theme	agar	1051:1054	arg1	bath					1064:1067	an edible, removable agar support bath	1030:1067	an edible, removable agar support bath	1030:1067	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	1	43	theme	muscle	168:173	arg1	tissues					175:181	sustainable, edible muscle tissues	148:181	sustainable, edible muscle tissues	148:181	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	1	44	theme	rising	203:208	arg1	demands					223:229	the rising meat product demands	199:229	the rising meat product demands	199:229	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	0	45	theme	cultivated	50:59	arg1	development					66:76	cultivated meat development	50:76	cultivated meat development	50:76	3D-printable plant protein-enriched scaffolds for cultivated meat development.					
35421802	3	46	theme	potential	720:728	arg1	bioinks					730:736	potential bioinks	720:736	potential bioinks for cellular printing	720:758	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	46	theme	potential	720:728	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	5	47	theme	support	1056:1062	arg1	bath					1064:1067	an edible, removable agar support bath	1030:1067	an edible, removable agar support bath	1030:1067	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	1	48	theme	meat	210:213	arg1	demands					223:229	the rising meat product demands	199:229	the rising meat product demands	199:229	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	4	49	theme	elevated	809:816	arg1	stability					818:826	elevated stability	809:826	elevated stability	809:826	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	1	50	theme	product	215:221	arg1	demands					223:229	the rising meat product demands	199:229	the rising meat product demands	199:229	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	8	51	theme	recovery	1259:1266	arg1	post-printing					1268:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing	1254:1280	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	3	52	theme	protein	517:523	arg1	isolate					525:531	pea protein isolate	513:531	pea protein isolate (PPI)	513:537	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	52	theme	protein	517:523	arg1	PPI					534:536	PPI	534:536	PPI	534:536	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	5	53	theme	edible	1033:1038	arg1	bath					1064:1067	an edible, removable agar support bath	1030:1067	an edible, removable agar support bath	1030:1067	Extrusion based 3D-printing with the two compositions was then developed, while using an edible, removable agar support bath.					
35421802	8	54	theme	∼80-90	1339:1344	arg1	%					1345:1345	%	1345:1345	%	1345:1345	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	0	55	theme	meat	61:64	arg1	development					66:76	cultivated meat development	50:76	cultivated meat development	50:76	3D-printable plant protein-enriched scaffolds for cultivated meat development.					
35421802	3	56	theme	cellular	742:749	arg1	printing					751:758	cellular printing	742:758	cellular printing	742:758	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	10	57	theme	allergic	1551:1558	arg1	risk					1560:1563	its low allergic risk	1543:1563	its low allergic risk	1543:1563	As animal-derived materials were avoided in our scaffold fabrication process, and pea-protein is known for its low allergic risk, these findings have great promise for further cultivated meat research.					
35421802	3	58	theme	RGD-modified	574:585	arg1	alginate					587:594	RGD-modified alginate	574:594	RGD-modified alginate (Alginate(RGD))	574:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	59	theme	isolate	525:531	arg1	bioinks					730:736	potential bioinks	720:736	potential bioinks for cellular printing	720:758	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	59	theme	isolate	525:531	arg1	scaffolds					670:678	prefabricated mold-based and 3D-printed scaffolds	630:678	prefabricated mold-based and 3D-printed scaffolds for BSC cultivation	630:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	59	theme	isolate	525:531	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	60	theme	pea	513:515	arg1	isolate					525:531	pea protein isolate	513:531	pea protein isolate (PPI)	513:537	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	60	theme	pea	513:515	arg1	PPI					534:536	PPI	534:536	PPI	534:536	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	61	theme	3D-printed	659:668	arg1	scaffolds					670:678	prefabricated mold-based and 3D-printed scaffolds	630:678	prefabricated mold-based and 3D-printed scaffolds for BSC cultivation	630:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	61	theme	3D-printed	659:668	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	4	62	theme	enriched	780:787	arg1	scaffolds					789:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	3	63	theme	isolate	555:561	arg1	bioinks					730:736	potential bioinks	720:736	potential bioinks for cellular printing	720:758	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	63	theme	isolate	555:561	arg1	scaffolds					670:678	prefabricated mold-based and 3D-printed scaffolds	630:678	prefabricated mold-based and 3D-printed scaffolds for BSC cultivation	630:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	63	theme	isolate	555:561	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	64	theme	prefabricated	630:642	arg1	scaffolds					670:678	prefabricated mold-based and 3D-printed scaffolds	630:678	prefabricated mold-based and 3D-printed scaffolds for BSC cultivation	630:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	64	theme	prefabricated	630:642	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	4	65	theme	protein	772:778	arg1	scaffolds					789:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds	761:797	Mold-based protein enriched scaffolds exhibited elevated stability and stiffness compared to ones made of Alginate(RGD) alone, while allowing unhindered BSC spreading and maturation.					
35421802	2	66	theme	complex	322:328	arg1	structures					330:339	thick and complex structures	312:339	thick and complex structures	312:339	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	3	67	theme	mold-based	644:653	arg1	scaffolds					670:678	prefabricated mold-based and 3D-printed scaffolds	630:678	prefabricated mold-based and 3D-printed scaffolds for BSC cultivation	630:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	3	67	theme	mold-based	644:653	arg1	Mixtures					501:508	Mixtures	501:508	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD))	501:610	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	6	68	dep	BSC	1144:1146	arg1	differentiation					1163:1177	differentiation	1163:1177	differentiation	1163:1177	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	6	68	dep	BSC	1144:1146	arg1	attachment					1148:1157	attachment	1148:1157	attachment	1148:1157	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	6	68	dep	BSC	1144:1146	arg1	BSC					1144:1146	BSC attachment and differentiation	1144:1177	BSC attachment and differentiation	1144:1177	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	8	69	theme	cultivation	1302:1312	arg1	configurations					1314:1327	two cultivation configurations	1298:1327	two cultivation configurations	1298:1327	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	1	70	theme	sustainable	148:158	arg1	tissues					175:181	sustainable, edible muscle tissues	148:181	sustainable, edible muscle tissues	148:181	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35421802	8	71	theme	%	1345:1345	arg1	viability					1347:1355	∼80-90% viability	1339:1355	∼80-90% viability	1339:1355	Cell recovery post-printing was observed in two cultivation configurations, reaching ∼80-90% viability over time.					
35421802	3	72	theme	BSC	684:686	arg1	cultivation					688:698	BSC cultivation	684:698	BSC cultivation	684:698	Mixtures of pea protein isolate (PPI) and soy protein isolate (SPI) with RGD-modified alginate (Alginate(RGD)) were evaluated as prefabricated mold-based and 3D-printed scaffolds for BSC cultivation, and ultimately, as potential bioinks for cellular printing.					
35421802	6	73	theme	well-defined	1110:1121	arg1	geometries					1123:1132	well-defined geometries	1110:1132	well-defined geometries	1110:1132	Successfully fabricated constructs with well-defined geometries supported BSC attachment and differentiation.					
35421802	2	74	theme	cells	477:481	arg1	maturation					489:498	bovine satellite cells (BSC) maturation	460:498	bovine satellite cells (BSC) maturation	460:498	As 3D-printing is a promising method for creating thick and complex structures, two plant-protein-enriched scaffolding compositions were primarily assessed in our work as 3D-printable platforms for bovine satellite cells (BSC) maturation.					
35421802	1	75	theme	global	241:246	arg1	consequences					248:259	their global consequences	235:259	their global consequences	235:259	Cultivated meat harnesses tissue engineering (TE) concepts to create sustainable, edible muscle tissues, for addressing the rising meat product demands and their global consequences.					
35385162	0	0	theme	Rabbit	86:91	arg1	Model					93:97	a Rabbit Model	84:97	a Rabbit Model	84:97	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	3	1	theme	cartilage	315:323	arg1	plasticity					325:334	auricular cartilage plasticity	305:334	auricular cartilage plasticity	305:334	Here, we aimed to examine why auricular cartilage plasticity appeared to diminish with age.					
35385162	5	2	theme	experimental	543:554	arg1	rabbits					518:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	5	2	theme	experimental	543:554	arg1	animal					556:561	the experimental animal	539:561	the experimental animal	539:561	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	16	3	theme	mature	1531:1536	arg1	cartilage					1538:1546	mature cartilage	1531:1546	mature cartilage	1531:1546	Young's modulus was significantly higher in mature cartilage.					
35385162	14	4	theme	elastin	1361:1367	arg1	fiber					1369:1373	elastin fiber	1361:1373	elastin fiber	1361:1373	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	10	5	theme	Safranin	1000:1007	arg1	O					1009:1009	Safranin O	1000:1009	Safranin O	1000:1009	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	13	6	theme	smaller	1210:1216	arg1	angles					1218:1223	smaller angles	1210:1223	smaller angles	1210:1223	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	15	7	theme	water	1422:1426	arg1	content					1428:1434	The water content	1418:1434	The water content	1418:1434	The water content, DNA content, and cell density decreased with age.					
35385162	4	8	theme	morphological	449:461	arg1	properties					463:472	the biomechanical, biochemical, and morphological properties	413:472	the biomechanical, biochemical, and morphological properties of auricular cartilage	413:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	0	9	from	Changes	0:6	arg1	Model					93:97	a Rabbit Model	84:97	a Rabbit Model	84:97	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	4	10	theme	age-related	390:400	arg1	changes					402:408	age-related changes	390:408	age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage	390:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	11	11	theme	DNA	1072:1074	arg1	content					1076:1082	DNA content	1072:1082	DNA content	1072:1082	Water content, DNA content, and cell density were also analyzed.					
35385162	8	12	theme	Folding	767:773	arg1	duration					775:782	Folding duration	767:782	Folding duration	767:782	Folding duration ranged from 1 day to 5 days to 10 days.					
35385162	17	13	dep	CONCLUSIONS	1549:1559	arg1	established					1583:1593	established	1583:1593	established an animal model of ear molding	1583:1624	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	17	13	dep	CONCLUSIONS	1549:1559	arg1	demonstrated					1630:1641	demonstrated	1630:1641	demonstrated that immature cartilage was associated with better plasticity	1630:1703	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	4	14	theme	cartilage	487:495	arg1	properties					463:472	the biomechanical, biochemical, and morphological properties	413:472	the biomechanical, biochemical, and morphological properties of auricular cartilage	413:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	18	15	theme	ECM	1799:1801	arg1	accumulation					1783:1794	the accumulation	1779:1794	the accumulation of ECM	1779:1801	We also found that the cartilage's biomechanical property increased with the accumulation of ECM.					
35385162	5	16	theme	New	506:508	arg1	rabbits					518:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	5	16	theme	New	506:508	arg1	animal					556:561	the experimental animal	539:561	the experimental animal	539:561	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	19	17	theme	shape	1856:1860	arg1	plasticity					1862:1871	age-related shape plasticity	1844:1871	age-related shape plasticity	1844:1871	The biomechanical change could underlie age-related shape plasticity.					
35385162	9	18	theme	retained	864:871	arg1	angle					878:882	the retained fold angle	860:882	the retained fold angle	860:882	Photographs were taken to calculate the retained fold angle.					
35385162	4	19	theme	auricular	477:485	arg1	cartilage					487:495	auricular cartilage	477:495	auricular cartilage	477:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	16	20	theme	Young	1487:1491	arg1	modulus					1495:1501	Young's modulus	1487:1501	Young's modulus	1487:1501	Young's modulus was significantly higher in mature cartilage.					
35385162	4	21	from	changes	402:408	arg1	properties					463:472	the biomechanical, biochemical, and morphological properties	413:472	the biomechanical, biochemical, and morphological properties of auricular cartilage	413:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	5	22	theme	Zealand	510:516	arg1	rabbits					518:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	5	22	theme	Zealand	510:516	arg1	animal					556:561	the experimental animal	539:561	the experimental animal	539:561	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	1	23	theme	auricular	165:173	arg1	deformities					175:185	auricular deformities	165:185	auricular deformities	165:185	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	9	24	theme	fold	873:876	arg1	angle					878:882	the retained fold angle	860:882	the retained fold angle	860:882	Photographs were taken to calculate the retained fold angle.					
35385162	10	25	theme	elastic	1012:1018	arg1	Gieson					1024:1029	elastic Van Gieson	1012:1029	elastic Van Gieson	1012:1029	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	13	26	theme	longer	1282:1287	arg1	time					1289:1292	a longer time	1280:1292	a longer time	1280:1292	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	13	27	contain	had	1206:1208	arg2	angles					1218:1223	smaller angles	1210:1223	smaller angles	1210:1223	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	13	27	contain	had	1206:1208	arg1	ears					1201:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	11	28	theme	cell	1089:1092	arg1	density					1094:1100	cell density	1089:1100	cell density	1089:1100	Water content, DNA content, and cell density were also analyzed.					
35385162	10	29	theme	Van	1020:1022	arg1	Gieson					1024:1029	elastic Van Gieson	1012:1029	elastic Van Gieson	1012:1029	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	15	30	theme	cell	1454:1457	arg1	density					1459:1465	cell density	1454:1465	cell density	1454:1465	The water content, DNA content, and cell density decreased with age.					
35385162	4	31	theme	biochemical	432:442	arg1	properties					463:472	the biomechanical, biochemical, and morphological properties	413:472	the biomechanical, biochemical, and morphological properties of auricular cartilage	413:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	17	32	theme	ear	1614:1616	arg1	molding					1618:1624	ear molding	1614:1624	ear molding	1614:1624	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	14	33	theme	Cartilage	1295:1303	arg1	compositions					1312:1323	Cartilage matrix compositions	1295:1323	Cartilage matrix compositions	1295:1323	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	33	theme	Cartilage	1295:1303	arg1	glycosaminoglycan					1336:1352	glycosaminoglycan	1336:1352	glycosaminoglycan (GAG)	1336:1358	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	33	theme	Cartilage	1295:1303	arg1	fiber					1369:1373	elastin fiber	1361:1373	elastin fiber	1361:1373	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	33	theme	Cartilage	1295:1303	arg1	collagen					1380:1387	collagen	1380:1387	collagen	1380:1387	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	7	34	theme	adhesive	741:748	arg1	strips					759:764	adhesive fixation strips	741:764	adhesive fixation strips	741:764	Rabbits' ears were splinted and folded using adhesive fixation strips.					
35385162	0	35	theme	Auricular	23:31	arg1	Plasticity					43:52	Age-related Auricular Cartilage Plasticity	11:52	Age-related Auricular Cartilage Plasticity	11:52	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	10	36	theme	extracellular	910:922	arg1	ECM					932:934	ECM	932:934	ECM	932:934	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	10	36	theme	extracellular	910:922	arg1	matrix					924:929	extracellular matrix	910:929	extracellular matrix (ECM) content	910:943	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	17	37	theme	better	1687:1692	arg1	plasticity					1694:1703	better plasticity	1687:1703	better plasticity	1687:1703	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	17	38	theme	molding	1618:1624	arg1	model					1605:1609	an animal model	1595:1609	an animal model of ear molding	1595:1624	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	1	39	theme	OBJECTIVES	100:109	arg1	molding					115:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	1	39	theme	OBJECTIVES	100:109	arg1	technique					138:146	an emerging technique	126:146	an emerging technique that can correct auricular deformities	126:185	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	6	40	theme	young	637:641	arg1	2M					654:655	2M	654:655	2M	654:655	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	6	40	theme	young	637:641	arg1	[2 months					643:651	young [2 months	637:651	young [2 months (2M)]	637:657	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	0	41	theme	Age-related	11:21	arg1	Plasticity					43:52	Age-related Auricular Cartilage Plasticity	11:52	Age-related Auricular Cartilage Plasticity	11:52	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	12	42	theme	Nano	1169:1172	arg1	indenter					1174:1181	a Nano indenter	1167:1181	a Nano indenter	1167:1181	Biomechanical properties were measured using a Nano indenter.					
35385162	2	43	theme	Treatment	188:196	arg1	time					209:212	Treatment initiation time	188:212	Treatment initiation time	188:212	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	43	theme	Treatment	188:196	arg1	determinant					247:257	the most important prognostic determinant	217:257	the most important prognostic determinant of ear molding	217:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	1	44	theme	Ear	111:113	arg1	molding					115:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	1	44	theme	Ear	111:113	arg1	technique					138:146	an emerging technique	126:146	an emerging technique that can correct auricular deformities	126:185	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	14	45	theme	matrix	1305:1310	arg1	compositions					1312:1323	Cartilage matrix compositions	1295:1323	Cartilage matrix compositions	1295:1323	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	45	theme	matrix	1305:1310	arg1	glycosaminoglycan					1336:1352	glycosaminoglycan	1336:1352	glycosaminoglycan (GAG)	1336:1358	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	45	theme	matrix	1305:1310	arg1	fiber					1369:1373	elastin fiber	1361:1373	elastin fiber	1361:1373	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	14	45	theme	matrix	1305:1310	arg1	collagen					1380:1387	collagen	1380:1387	collagen	1380:1387	Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development.					
35385162	0	46	theme	Plasticity	43:52	arg1	Changes					0:6	Changes	0:6	Changes of Age-related Auricular Cartilage Plasticity	0:52	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	0	46	theme	Plasticity	43:52	arg1	Property					72:79	Biomechanical Property	58:79	Biomechanical Property	58:79	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	13	47	theme	RESULTS	1184:1190	arg1	ears					1201:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	5	48	theme	METHODS	498:504	arg1	rabbits					518:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	5	48	theme	METHODS	498:504	arg1	animal					556:561	the experimental animal	539:561	the experimental animal	539:561	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	19	49	theme	biomechanical	1808:1820	arg1	change					1822:1827	The biomechanical change	1804:1827	The biomechanical change	1804:1827	The biomechanical change could underlie age-related shape plasticity.					
35385162	0	50	theme	Cartilage	33:41	arg1	Plasticity					43:52	Age-related Auricular Cartilage Plasticity	11:52	Age-related Auricular Cartilage Plasticity	11:52	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	6	51	dep	0 day	596:600	arg1	rabbits					687:693	rabbits	687:693	rabbits	687:693	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	13	52	theme	Immature	1192:1199	arg1	ears					1201:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears	1184:1204	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	2	53	theme	prognostic	236:245	arg1	time					209:212	Treatment initiation time	188:212	Treatment initiation time	188:212	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	53	theme	prognostic	236:245	arg1	determinant					247:257	the most important prognostic determinant	217:257	the most important prognostic determinant of ear molding	217:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	10	54	theme	matrix	924:929	arg1	content					937:943	extracellular matrix (ECM) content	910:943	extracellular matrix (ECM) content	910:943	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	0	55	theme	Biomechanical	58:70	arg1	Property					72:79	Biomechanical Property	58:79	Biomechanical Property	58:79	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	7	56	theme	fixation	750:757	arg1	strips					759:764	adhesive fixation strips	741:764	adhesive fixation strips	741:764	Rabbits' ears were splinted and folded using adhesive fixation strips.					
35385162	17	57	theme	animal	1598:1603	arg1	model					1605:1609	an animal model	1595:1609	an animal model of ear molding	1595:1624	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	0	58	from	Property	72:79	arg1	Model					93:97	a Rabbit Model	84:97	a Rabbit Model	84:97	Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.					
35385162	2	59	theme	important	226:234	arg1	time					209:212	Treatment initiation time	188:212	Treatment initiation time	188:212	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	59	theme	important	226:234	arg1	determinant					247:257	the most important prognostic determinant	217:257	the most important prognostic determinant of ear molding	217:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	15	60	theme	DNA	1437:1439	arg1	content					1441:1447	DNA content	1437:1447	DNA content	1437:1447	The water content, DNA content, and cell density decreased with age.					
35385162	6	61	theme	immature	576:583	arg1	0 day					596:600	immature [postnatal 0 day	576:600	immature [postnatal 0 day (P0)	576:605	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	6	61	theme	immature	576:583	arg1	P0					603:604	P0	603:604	P0	603:604	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	3	62	theme	auricular	305:313	arg1	plasticity					325:334	auricular cartilage plasticity	305:334	auricular cartilage plasticity	305:334	Here, we aimed to examine why auricular cartilage plasticity appeared to diminish with age.					
35385162	12	63	theme	Biomechanical	1122:1134	arg1	properties					1136:1145	Biomechanical properties	1122:1145	Biomechanical properties	1122:1145	Biomechanical properties were measured using a Nano indenter.					
35385162	4	64	theme	biomechanical	417:429	arg1	properties					463:472	the biomechanical, biochemical, and morphological properties	413:472	the biomechanical, biochemical, and morphological properties of auricular cartilage	413:495	Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage.					
35385162	20	65	theme	EVIDENCE	1883:1890	arg1	LEVEL					1874:1878	LEVEL	1874:1878	LEVEL OF EVIDENCE	1874:1890	LEVEL OF EVIDENCE NA Laryngoscope, 133:88-94, 2023.					
35385162	10	66	theme	Cartilage	885:893	arg1	morphology					895:904	Cartilage morphology	885:904	Cartilage morphology	885:904	Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome).					
35385162	19	67	theme	age-related	1844:1854	arg1	plasticity					1862:1871	age-related shape plasticity	1844:1871	age-related shape plasticity	1844:1871	The biomechanical change could underlie age-related shape plasticity.					
35385162	18	68	theme	biomechanical	1741:1753	arg1	property					1755:1762	the cartilage's biomechanical property	1725:1762	the cartilage's biomechanical property	1725:1762	We also found that the cartilage's biomechanical property increased with the accumulation of ECM.					
35385162	13	69	theme	strip	1231:1235	arg1	removal					1237:1243	strip removal	1231:1243	strip removal	1231:1243	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
35385162	17	70	theme	immature	1648:1655	arg1	cartilage					1657:1665	immature cartilage	1648:1665	immature cartilage	1648:1665	CONCLUSIONS Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity.					
35385162	2	71	theme	molding	266:272	arg1	time					209:212	Treatment initiation time	188:212	Treatment initiation time	188:212	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	71	theme	molding	266:272	arg1	determinant					247:257	the most important prognostic determinant	217:257	the most important prognostic determinant of ear molding	217:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	1	72	theme	emerging	129:136	arg1	molding					115:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding	100:121	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	1	72	theme	emerging	129:136	arg1	technique					138:146	an emerging technique	126:146	an emerging technique that can correct auricular deformities	126:185	OBJECTIVES Ear molding is an emerging technique that can correct auricular deformities.					
35385162	2	73	theme	initiation	198:207	arg1	time					209:212	Treatment initiation time	188:212	Treatment initiation time	188:212	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	73	theme	initiation	198:207	arg1	determinant					247:257	the most important prognostic determinant	217:257	the most important prognostic determinant of ear molding	217:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	2	74	theme	ear	262:264	arg1	molding					266:272	ear molding	262:272	ear molding	262:272	Treatment initiation time is the most important prognostic determinant of ear molding.					
35385162	6	75	theme	mature	664:669	arg1	6M					682:683	6M	682:683	6M	682:683	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	6	75	theme	mature	664:669	arg1	[6 months					671:679	mature [6 months	664:679	mature [6 months (6M)]	664:685	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	5	76	used	used	531:534	arg2	rabbits					518:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits	498:524	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	5	76	used	used	531:534	arg2	animal					556:561	the experimental animal	539:561	the experimental animal	539:561	METHODS New Zealand rabbits were used as the experimental animal.					
35385162	6	77	theme	[postnatal	585:594	arg1	0 day					596:600	immature [postnatal 0 day	576:600	immature [postnatal 0 day (P0)	576:605	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	6	77	theme	[postnatal	585:594	arg1	P0					603:604	P0	603:604	P0	603:604	We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits.					
35385162	11	78	theme	Water	1057:1061	arg1	content					1063:1069	Water content	1057:1069	Water content	1057:1069	Water content, DNA content, and cell density were also analyzed.					
35385162	13	79	theme	angled	1254:1259	arg1	deformation					1261:1271	the angled deformation	1250:1271	the angled deformation	1250:1271	RESULTS Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time.					
36323015	7	0	theme	54.4 	917:921	arg1	%					922:922	%	922:922	%	922:922	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	5	1	theme	droplets	778:785	arg1	congregating					787:798	droplets congregating	778:798	droplets congregating	778:798	CLSM showed that the oil droplets were coated with covering layer formed by ZPAAPs, which effectively prevented droplets congregating.					
36323015	7	2	contain	contained	907:915	arg2	ZPAAPEs					893:899	ZPAAPEs	893:899	ZPAAPEs	893:899	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	7	2	contain	contained	907:915	arg1	ZPAAPEs					893:899	ZPAAPEs	893:899	ZPAAPEs	893:899	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	7	2	contain	contained	907:915	arg1	addition					883:890	addition	883:890	addition	883:890	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	7	2	contain	contained	907:915	arg2	curcumin					924:931	54.4 % curcumin	917:931	54.4 % curcumin after storage for 15 d.	917:955	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	0	3	theme	delivery	110:117	arg1	studies					119:125	delivery studies	110:125	delivery studies	110:125	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	7	4	theme	curcumin	984:991	arg1	bioavailability					965:979	the bioavailability	961:979	the bioavailability of curcumin	961:991	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	3	5	theme	visual	560:565	arg1	observation					567:577	visual observation	560:577	visual observation	560:577	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	1	6	used	used	163:166	arg2	Proanthocyanidins					128:144	Proanthocyanidins	128:144	Proanthocyanidins (Pas)	128:150	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	1	6	used	used	163:166	arg2	Pas					147:149	Pas	147:149	Pas	147:149	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	2	7	theme	Pas	285:287	arg1	effect					275:280	the effect	271:280	the effect of Pas on the stability of Pickering emulsions	271:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	4	8	from	stable	597:602	arg1	range					636:640	the range	632:640	the range of 0.1 ∼ 0.7 oil phase	632:663	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	8	9	from	delivery	1121:1128	arg1	fields					1161:1166	the food and pharmaceutical fields	1133:1166	the food and pharmaceutical fields	1133:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	6	10	theme	rheological	805:815	arg1	results					817:823	The rheological results	801:823	The rheological results	801:823	The rheological results indicated that ZPAAPEs had elastic gel-like structure.					
36323015	2	11	theme	effect	275:280	arg1	advantage					258:266	advantage	258:266	advantage of the effect of Pas on the stability of Pickering emulsions	258:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	2	12	theme	potential	467:475	arg1	capacity					486:493	potential delivery capacity	467:493	potential delivery capacity	467:493	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	8	13	theme	pharmaceutical	1146:1159	arg1	fields					1161:1166	the food and pharmaceutical fields	1133:1166	the food and pharmaceutical fields	1133:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	2	14	theme	Pickering	309:317	arg1	emulsions					319:327	Pickering emulsions	309:327	Pickering emulsions	309:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	8	15	theme	nutrient	1112:1119	arg1	delivery					1121:1128	nutrient delivery	1112:1128	nutrient delivery in the food and pharmaceutical fields	1112:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	0	16	theme	Pickering	0:8	arg1	emulsions					10:18	Pickering emulsions	0:18	Pickering emulsions	0:18	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	8	17	theme	controllable	1060:1071	arg1	fabrication					1073:1083	the controllable fabrication	1056:1083	the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields	1056:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	2	18	from	advantage	258:266	arg1	stability					296:304	the stability	292:304	the stability of Pickering emulsions	292:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	1	19	theme	functional	190:199	arg1	foods					201:205	functional foods	190:205	functional foods	190:205	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	8	20	theme	Pickering	1088:1096	arg1	emulsions					1098:1106	Pickering emulsions	1088:1106	Pickering emulsions	1088:1106	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	1	21	theme	foods	201:205	arg1	preparation					175:185	the preparation	171:185	the preparation of functional foods due to their diverse biological activities	171:248	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	2	22	theme	Pickering	442:450	arg1	emulsions					452:460	Pickering emulsions	442:460	Pickering emulsions	442:460	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	3	23	located	found	551:555	arg2	appearance					500:509	The appearance	496:509	The appearance of the emulsion	496:525	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	3	23	located	found	551:555	arg2	pink					531:534	pink	531:534	pink which could be found in visual observation	531:577	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	3	23	located	found	551:555	arg1	observation					567:577	visual observation	560:577	visual observation	560:577	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	6	24	contain	had	848:850	arg2	structure					869:877	elastic gel-like structure	852:877	elastic gel-like structure	852:877	The rheological results indicated that ZPAAPEs had elastic gel-like structure.					
36323015	6	24	contain	had	848:850	arg1	ZPAAPEs					840:846	ZPAAPEs	840:846	ZPAAPEs	840:846	The rheological results indicated that ZPAAPEs had elastic gel-like structure.					
36323015	0	25	theme	ternary	64:70	arg1	ZPAAPs					84:89	ZPAAPs	84:89	ZPAAPs	84:89	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	0	25	theme	ternary	64:70	arg1	composites					72:81	zein-proanthocyanidins-pectin ternary composites	34:81	zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies	34:125	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	5	26	theme	covering	717:724	arg1	layer					726:730	covering layer	717:730	covering layer formed by ZPAAPs, which effectively prevented droplets congregating	717:798	CLSM showed that the oil droplets were coated with covering layer formed by ZPAAPs, which effectively prevented droplets congregating.					
36323015	4	27	theme	phase	659:663	arg1	range					636:640	the range	632:640	the range of 0.1 ∼ 0.7 oil phase	632:663	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	0	28	theme	zein-proanthocyanidins-pectin	34:62	arg1	ZPAAPs					84:89	ZPAAPs	84:89	ZPAAPs	84:89	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	0	28	theme	zein-proanthocyanidins-pectin	34:62	arg1	composites					72:81	zein-proanthocyanidins-pectin ternary composites	34:81	zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies	34:125	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	8	29	theme	emulsions	1098:1106	arg1	fabrication					1073:1083	the controllable fabrication	1056:1083	the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields	1056:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	1	30	dep	diverse	220:226	arg1	biological					228:237	biological	228:237	biological	228:237	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	0	31	dep	composites	72:81	arg1	Construction					93:104	Construction	93:104	Construction	93:104	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	0	31	dep	composites	72:81	arg1	studies					119:125	delivery studies	110:125	delivery studies	110:125	Pickering emulsions stabilized by zein-proanthocyanidins-pectin ternary composites (ZPAAPs): Construction and delivery studies.					
36323015	4	32	theme	oil	655:657	arg1	phase					659:663	0.1 ∼ 0.7 oil phase	645:663	0.1 ∼ 0.7 oil phase	645:663	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	8	33	theme	food	1137:1140	arg1	fields					1161:1166	the food and pharmaceutical fields	1133:1166	the food and pharmaceutical fields	1133:1166	These studies may contribute to the controllable fabrication of Pickering emulsions for nutrient delivery in the food and pharmaceutical fields.					
36323015	2	34	theme	delivery	477:484	arg1	capacity					486:493	potential delivery capacity	467:493	potential delivery capacity	467:493	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	5	35	theme	oil	687:689	arg1	droplets					691:698	the oil droplets	683:698	the oil droplets	683:698	CLSM showed that the oil droplets were coated with covering layer formed by ZPAAPs, which effectively prevented droplets congregating.					
36323015	7	36	theme	%	1015:1015	arg1	±					1017:1017	39.7 % ± 0.3	1010:1021	39.7 % ± 0.3	1010:1021	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	3	37	theme	emulsion	518:525	arg1	pink					531:534	pink	531:534	pink which could be found in visual observation	531:577	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	3	37	theme	emulsion	518:525	arg1	appearance					500:509	The appearance	496:509	The appearance of the emulsion	496:525	The appearance of the emulsion was pink which could be found in visual observation.					
36323015	6	38	theme	gel-like	860:867	arg1	structure					869:877	elastic gel-like structure	852:877	elastic gel-like structure	852:877	The rheological results indicated that ZPAAPEs had elastic gel-like structure.					
36323015	2	39	from	effect	275:280	arg1	stability					296:304	the stability	292:304	the stability of Pickering emulsions	292:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	1	40	theme	diverse	220:226	arg1	activities					239:248	their diverse biological activities	214:248	their diverse biological activities	214:248	Proanthocyanidins (Pas) are widely used in the preparation of functional foods due to their diverse biological activities.					
36323015	6	41	theme	elastic	852:858	arg1	structure					869:877	elastic gel-like structure	852:877	elastic gel-like structure	852:877	The rheological results indicated that ZPAAPEs had elastic gel-like structure.					
36323015	2	42	theme	emulsions	319:327	arg1	stability					296:304	the stability	292:304	the stability of Pickering emulsions	292:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	7	43	theme	%	922:922	arg1	curcumin					924:931	54.4 % curcumin	917:931	54.4 % curcumin after storage for 15 d.	917:955	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	4	44	from	range	636:640	arg1	stable					597:602	stable	597:602	stable	597:602	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	4	44	from	range	636:640	arg1	emulsion					584:591	The emulsion	580:591	The emulsion	580:591	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	7	45	theme	39.7 	1010:1014	arg1	%					1015:1015	%	1015:1015	%	1015:1015	In addition, ZPAAPEs still contained 54.4 % curcumin after storage for 15 d. And the bioavailability of curcumin was increased to 39.7 % ± 0.3.					
36323015	2	46	theme	ternary	387:393	arg1	ZPAAPs					407:412	ZPAAPs	407:412	ZPAAPs	407:412	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	2	46	theme	ternary	387:393	arg1	composites					395:404	the zein-proanthocyanidins-pectin ternary composites	353:404	the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer	353:427	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	4	47	theme	long-term	611:619	arg1	storage					621:627	long-term storage	611:627	long-term storage	611:627	The emulsion was stable during long-term storage in the range of 0.1 ∼ 0.7 oil phase.					
36323015	2	48	theme	zein-proanthocyanidins-pectin	357:385	arg1	ZPAAPs					407:412	ZPAAPs	407:412	ZPAAPs	407:412	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	2	48	theme	zein-proanthocyanidins-pectin	357:385	arg1	composites					395:404	the zein-proanthocyanidins-pectin ternary composites	353:404	the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer	353:427	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
36323015	2	49	from	stability	296:304	arg1	advantage					258:266	advantage	258:266	advantage of the effect of Pas on the stability of Pickering emulsions	258:327	Taking advantage of the effect of Pas on the stability of Pickering emulsions, this study constructed the zein-proanthocyanidins-pectin ternary composites (ZPAAPs) as stabilizer to establish Pickering emulsions with potential delivery capacity.					
35468430	9	0	theme	emergency	1827:1835	arg1	treatments					1837:1846	emergency treatments	1827:1846	emergency treatments	1827:1846	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	4	1	theme	crosslinked	706:716	arg1	hydrogels					728:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	4	2	theme	hydrogels	728:736	arg1	types					658:662	two types	654:662	two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	654:736	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	2	3	theme	sufficient	384:393	arg1	strength					406:413	sufficient mechanical strength	384:413	sufficient mechanical strength	384:413	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	9	4	theme	high	1787:1790	arg1	strength					1792:1799	high strength	1787:1799	high strength	1787:1799	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	4	5	theme	microgels	626:634	arg1	kinds					617:621	Three kinds	611:621	Three kinds of microgels	611:634	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	8	6	theme	emergency	1369:1377	arg1	performance					1391:1401	emergency application performance	1369:1401	emergency application performance	1369:1401	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	7	7	theme	whole	1152:1156	arg1	process					1168:1174	the whole operation process	1148:1174	the whole operation process	1148:1174	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	5	8	theme	high-strength	919:931	arg1	hydrogels					933:941	high-strength hydrogels	919:941	high-strength hydrogels	919:941	After mixing with water, all these microgels could undergo a quick hydration process and then transform into high-strength hydrogels in situ through H-bonds.					
35468430	4	9	theme	preformed	718:726	arg1	hydrogels					728:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	7	10	theme	operation	1158:1166	arg1	process					1168:1174	the whole operation process	1148:1174	the whole operation process	1148:1174	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	2	11	theme	formed	309:314	arg1	hydrogels					316:324	current in-situ formed hydrogels	293:324	current in-situ formed hydrogels	293:324	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	2	12	theme	laborious	336:344	arg1	process					368:374	a laborious precursor preparation process	334:374	a laborious precursor preparation process	334:374	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	4	13	theme	hydrogen	667:674	arg1	H-bonds					683:689	H-bonds	683:689	H-bonds	683:689	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	4	13	theme	hydrogen	667:674	arg1	bonds					676:680	hydrogen bonds	667:680	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC)	667:704	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	3	14	theme	emergency	590:598	arg1	treatment					600:608	emergency treatment	590:608	emergency treatment	590:608	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	9	15	with	hydrogels	1734:1742	arg1	ability					1775:1781	convenient gel-transition ability	1749:1781	convenient gel-transition ability	1749:1781	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	9	15	with	hydrogels	1734:1742	arg1	strength					1792:1799	high strength	1787:1799	high strength	1787:1799	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	2	16	theme	in-situ	301:307	arg1	hydrogels					316:324	current in-situ formed hydrogels	293:324	current in-situ formed hydrogels	293:324	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	1	17	theme	convenient	151:160	arg1	process					177:183	a convenient gel transition process	149:183	a convenient gel transition process	149:183	High-strength hydrogels formed in situ through a convenient gel transition process are highly desirable for emergency treatment due to their ability to quickly respond to accidents.					
35468430	8	18	theme	stored	1574:1579	arg1	microgels					1581:1589	the stored microgels	1570:1589	the stored microgels to hemostasis	1570:1603	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	9	19	theme	formed	1712:1717	arg1	hydrogels					1734:1742	the in-situ formed microgel-based hydrogels	1700:1742	the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength	1700:1799	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	3	20	theme	transition	498:507	arg1	capable					468:474	capable	468:474	capable	468:474	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	2	21	theme	current	293:299	arg1	hydrogels					316:324	current in-situ formed hydrogels	293:324	current in-situ formed hydrogels	293:324	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	6	22	theme	hydration	1104:1112	arg1	cost					1089:1092	the cost	1085:1092	the cost of longer hydration	1085:1112	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	6	22	theme	hydration	1104:1112	arg1	time					1128:1131	operation time	1118:1131	operation time	1118:1131	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	5	23	theme	hydration	877:885	arg1	process					887:893	a quick hydration process	869:893	a quick hydration process	869:893	After mixing with water, all these microgels could undergo a quick hydration process and then transform into high-strength hydrogels in situ through H-bonds.					
35468430	7	24	theme	resultant	1226:1234	arg1	hydrogels					1236:1244	the resultant hydrogels	1222:1244	the resultant hydrogels	1222:1244	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	8	25	theme	application	1379:1389	arg1	performance					1391:1401	emergency application performance	1369:1401	emergency application performance	1369:1401	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	6	26	theme	higher	1047:1052	arg1	strength					1065:1072	higher mechanical strength	1047:1072	higher mechanical strength	1047:1072	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	8	27	theme	hemostatic	1428:1437	arg1	CHP					1447:1449	commercial chitosan hemostatic powder (CHP)	1408:1450	commercial chitosan hemostatic powder (CHP)	1408:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	6	28	theme	operation	1118:1126	arg1	time					1128:1131	operation time	1118:1131	operation time	1118:1131	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	7	29	theme	megapascal-level	1270:1285	arg1	strength					1299:1306	maximally megapascal-level compressive strength	1260:1306	maximally megapascal-level compressive strength	1260:1306	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	1	30	theme	High-strength	102:114	arg1	hydrogels					116:124	High-strength hydrogels	102:124	High-strength hydrogels formed in situ through a convenient gel transition process	102:183	High-strength hydrogels formed in situ through a convenient gel transition process are highly desirable for emergency treatment due to their ability to quickly respond to accidents.					
35468430	7	31	theme	storage	1331:1337	arg1	modulus					1339:1345	kilopascal storage modulus	1320:1345	kilopascal storage modulus	1320:1345	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	3	32	theme	microgels	448:456	arg1	series					438:443	a series	436:443	a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment	436:608	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	0	33	theme	Microgel-integrated	0:18	arg1	hydrogel					50:57	Microgel-integrated, high-strength in-situ formed hydrogel	0:57	Microgel-integrated, high-strength in-situ formed hydrogel	0:57	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	8	34	theme	whole	1540:1544	arg1	process					1546:1552	the whole process	1536:1552	the whole process from taking out the stored microgels to hemostasis	1536:1603	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	4	35	theme	excellent	757:765	arg1	stability					767:775	excellent stability	757:775	excellent stability	757:775	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	8	36	theme	powder	1439:1444	arg1	CHP					1447:1449	commercial chitosan hemostatic powder (CHP)	1408:1450	commercial chitosan hemostatic powder (CHP)	1408:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	1	37	theme	emergency	210:218	arg1	treatment					220:228	emergency treatment	210:228	emergency treatment due to their ability to quickly respond to accidents	210:281	High-strength hydrogels formed in situ through a convenient gel transition process are highly desirable for emergency treatment due to their ability to quickly respond to accidents.					
35468430	7	38	theme	several	1201:1207	arg1	minutes					1209:1215	several minutes	1201:1215	several minutes	1201:1215	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	9	39	theme	convenient	1749:1758	arg1	ability					1775:1781	convenient gel-transition ability	1749:1781	convenient gel-transition ability	1749:1781	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	0	40	dep	formed	43:48	arg1	in-situ					35:41	in-situ	35:41	in-situ	35:41	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	4	41	link	crosslinked	706:716	arg1	hydrogels					728:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	667:736	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	6	42	link	crosslinked	998:1008	arg1	microgels					1010:1018	stronger H-bond crosslinked microgels	982:1018	stronger H-bond crosslinked microgels	982:1018	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	3	43	theme	in-situ	490:496	arg1	transition					498:507	convenient in-situ transition	479:507	convenient in-situ transition to high-strength hydrogels from their easily portable form	479:566	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	6	44	theme	crosslinked	998:1008	arg1	microgels					1010:1018	stronger H-bond crosslinked microgels	982:1018	stronger H-bond crosslinked microgels	982:1018	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	4	45	dep	crosslinked	706:716	arg1	H-bonds					683:689	H-bonds	683:689	H-bonds	683:689	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	4	45	dep	crosslinked	706:716	arg1	bonds					676:680	hydrogen bonds	667:680	hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC)	667:704	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	8	46	theme	performance	1391:1401	arg1	comparison					1355:1364	the comparison	1351:1364	the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP)	1351:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	3	47	theme	portable	554:561	arg1	form					563:566	their easily portable form	541:566	their easily portable form	541:566	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	6	48	theme	H-bond	991:996	arg1	microgels					1010:1018	stronger H-bond crosslinked microgels	982:1018	stronger H-bond crosslinked microgels	982:1018	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	7	49	dep	megapascal-level	1270:1285	arg1	compressive					1287:1297	compressive	1287:1297	compressive	1287:1297	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	8	50	with	comparison	1355:1364	arg1	CHP					1447:1449	commercial chitosan hemostatic powder (CHP)	1408:1450	commercial chitosan hemostatic powder (CHP)	1408:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	4	51	dep	H-bonds	683:689	arg1	OH⋯OC					692:696	OH⋯OC	692:696	OH⋯OC	692:696	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	4	51	dep	H-bonds	683:689	arg1	NH⋯OC					699:703	NH⋯OC	699:703	NH⋯OC	699:703	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	6	52	theme	longer	1097:1102	arg1	hydration					1104:1112	longer hydration	1097:1112	longer hydration	1097:1112	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	0	53	theme	formed	43:48	arg1	hydrogel					50:57	Microgel-integrated, high-strength in-situ formed hydrogel	0:57	Microgel-integrated, high-strength in-situ formed hydrogel	0:57	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	6	54	theme	stronger	982:989	arg1	microgels					1010:1018	stronger H-bond crosslinked microgels	982:1018	stronger H-bond crosslinked microgels	982:1018	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	3	55	theme	convenient	479:488	arg1	transition					498:507	convenient in-situ transition	479:507	convenient in-situ transition to high-strength hydrogels from their easily portable form	479:566	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	0	56	theme	timely	67:72	arg1	treatment					91:99	timely emergency trauma treatment	67:99	timely emergency trauma treatment	67:99	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	8	57	theme	chitosan	1419:1426	arg1	CHP					1447:1449	commercial chitosan hemostatic powder (CHP)	1408:1450	commercial chitosan hemostatic powder (CHP)	1408:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	7	58	theme	modulus	1339:1345	arg1	tens					1312:1315	tens	1312:1315	tens of kilopascal storage modulus	1312:1345	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	7	58	theme	modulus	1339:1345	arg1	strength					1299:1306	maximally megapascal-level compressive strength	1260:1306	maximally megapascal-level compressive strength	1260:1306	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	9	59	theme	microgel-based	1719:1732	arg1	hydrogels					1734:1742	the in-situ formed microgel-based hydrogels	1700:1742	the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength	1700:1799	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	1	60	theme	transition	166:175	arg1	process					177:183	a convenient gel transition process	149:183	a convenient gel transition process	149:183	High-strength hydrogels formed in situ through a convenient gel transition process are highly desirable for emergency treatment due to their ability to quickly respond to accidents.					
35468430	3	61	from	form	563:566	arg1	transition					498:507	convenient in-situ transition	479:507	convenient in-situ transition to high-strength hydrogels from their easily portable form	479:566	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	4	62	attach	derived	641:647	arg2	kinds					617:621	Three kinds	611:621	Three kinds of microgels	611:634	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	4	62	attach	derived	641:647	arg1	types					658:662	two types	654:662	two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels	654:736	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	6	63	with	hydrogels	1032:1040	arg1	strength					1065:1072	higher mechanical strength	1047:1072	higher mechanical strength	1047:1072	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35468430	2	64	theme	preparation	356:366	arg1	process					368:374	a laborious precursor preparation process	334:374	a laborious precursor preparation process	334:374	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	9	65	theme	great	1808:1812	arg1	potential					1814:1822	great potential	1808:1822	great potential	1808:1822	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	4	66	theme	room	792:795	arg1	temperature					797:807	room temperature	792:807	room temperature	792:807	Three kinds of microgels were derived from two types of hydrogen bonds (H-bonds; OH⋯OC, NH⋯OC) crosslinked preformed hydrogels, and all exhibited excellent stability when stored at room temperature.					
35468430	2	67	theme	precursor	346:354	arg1	process					368:374	a laborious precursor preparation process	334:374	a laborious precursor preparation process	334:374	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	8	68	theme	commercial	1408:1417	arg1	CHP					1447:1449	commercial chitosan hemostatic powder (CHP)	1408:1450	commercial chitosan hemostatic powder (CHP)	1408:1450	In the comparison of emergency application performance with commercial chitosan hemostatic powder (CHP), we found that the microgels could stop accidental bleeding almost immediately, and the whole process from taking out the stored microgels to hemostasis could be completed within 15 s, which was superior to CHP.					
35468430	7	69	theme	kilopascal	1320:1329	arg1	modulus					1339:1345	kilopascal storage modulus	1320:1345	kilopascal storage modulus	1320:1345	Nevertheless, the whole operation process could be finished within several minutes, and the resultant hydrogels could exhibit maximally megapascal-level compressive strength and tens of kilopascal storage modulus.					
35468430	0	70	theme	trauma	84:89	arg1	treatment					91:99	timely emergency trauma treatment	67:99	timely emergency trauma treatment	67:99	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	5	71	theme	quick	871:875	arg1	process					887:893	a quick hydration process	869:893	a quick hydration process	869:893	After mixing with water, all these microgels could undergo a quick hydration process and then transform into high-strength hydrogels in situ through H-bonds.					
35468430	1	72	theme	gel	162:164	arg1	process					177:183	a convenient gel transition process	149:183	a convenient gel transition process	149:183	High-strength hydrogels formed in situ through a convenient gel transition process are highly desirable for emergency treatment due to their ability to quickly respond to accidents.					
35468430	3	73	theme	high-strength	512:524	arg1	hydrogels					526:534	high-strength hydrogels	512:534	high-strength hydrogels	512:534	Herein, we reported a series of microgels that were capable of convenient in-situ transition to high-strength hydrogels from their easily portable form, thereby facilitating emergency treatment.					
35468430	0	74	theme	emergency	74:82	arg1	treatment					91:99	timely emergency trauma treatment	67:99	timely emergency trauma treatment	67:99	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	0	75	dep	Microgel-integrated	0:18	arg1	high-strength					21:33	high-strength	21:33	high-strength	21:33	Microgel-integrated, high-strength in-situ formed hydrogel enables timely emergency trauma treatment.					
35468430	9	76	dep	formed	1712:1717	arg1	in-situ					1704:1710	in-situ	1704:1710	in-situ	1704:1710	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	2	77	theme	mechanical	395:404	arg1	strength					406:413	sufficient mechanical strength	384:413	sufficient mechanical strength	384:413	However, current in-situ formed hydrogels require a laborious precursor preparation process or lack sufficient mechanical strength.					
35468430	9	78	theme	gel-transition	1760:1773	arg1	ability					1775:1781	convenient gel-transition ability	1749:1781	convenient gel-transition ability	1749:1781	Overall, the results indicated that the in-situ formed microgel-based hydrogels with convenient gel-transition ability and high strength showed great potential in emergency treatments.					
35468430	6	79	theme	mechanical	1054:1063	arg1	strength					1065:1072	higher mechanical strength	1047:1072	higher mechanical strength	1047:1072	Specifically, stronger H-bond crosslinked microgels could build hydrogels with higher mechanical strength, albeit at the cost of longer hydration and operation time.					
35856349	6	0	theme	Next	1115:1118	arg1	UK					1162:1163	UK	1162:1163	UK	1162:1163	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	0	theme	Next	1115:1118	arg1	points					1144:1149	Pro Taper Next Obturators gutta-percha points	1105:1149	Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1105:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	16	1	theme	resin	2250:2254	arg1	cement					2265:2270	The self-adhesive resin modified cement	2232:2270	The self-adhesive resin modified cement	2232:2270	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	16	2	theme	photo-activated	2349:2363	arg1	photosensitizer					2365:2379	respective photo-activated photosensitizer	2338:2379	respective photo-activated photosensitizer (chitosan, TB & Clp6)	2338:2401	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	1	3	theme	self-adhesive	242:254	arg1	resin					256:260	self-adhesive resin	242:260	self-adhesive resin	242:260	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	15	4	theme	significant	2137:2147	arg1	difference					2149:2158	statistically significant difference	2123:2158	statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05)	2123:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	8	5	dep	G1	1377:1378	arg1	TB					1415:1416	13-15 mg/mL TB	1403:1416	13-15 mg/mL TB	1403:1416	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	8	5	dep	G1	1377:1378	arg1	chitosan					1381:1388	chitosan	1381:1388	G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6	1377:1429	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	8	5	dep	G1	1377:1378	arg1	G2					1399:1400	G2	1399:1400	G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6	1377:1429	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	8	5	dep	G1	1377:1378	arg1	Clp6					1426:1429	Clp6	1426:1429	G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6	1377:1429	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	8	5	dep	G1	1377:1378	arg1	G3					1422:1423	G3	1422:1423	G3	1422:1423	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	16	6	theme	utmost	2281:2286	arg1	strength					2293:2300	utmost bond strength	2281:2300	utmost bond strength	2281:2300	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	13	7	theme	prior	1882:1886	arg1	±					1949:1949	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	16	8	with	pre-treatment	2305:2317	arg1	photosensitizer					2365:2379	respective photo-activated photosensitizer	2338:2379	respective photo-activated photosensitizer (chitosan, TB & Clp6)	2338:2401	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	9	9	theme	modified	1509:1516	arg1	n=11					1540:1543	n=11	1540:1543	n=11	1540:1543	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	9	9	theme	modified	1509:1516	arg1	cement					1532:1537	conventional (n=11) and resin modified self-adhesive cement	1479:1537	conventional (n=11) and resin modified self-adhesive cement (n=11)	1479:1544	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	0	10	theme	modified	113:120	arg1	posts					138:142	resin modified composite fiber posts	107:142	resin modified composite fiber posts	107:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	8	11	theme	13-15	1403:1407	arg1	TB					1415:1416	13-15 mg/mL TB	1403:1416	13-15 mg/mL TB	1403:1416	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	0	12	theme	fiber	132:136	arg1	posts					138:142	resin modified composite fiber posts	107:142	resin modified composite fiber posts	107:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	16	13	dep	photosensitizer	2365:2379	arg1	Clp6					2397:2400	TB & Clp6	2392:2400	TB & Clp6	2392:2400	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	16	13	dep	photosensitizer	2365:2379	arg1	chitosan					2382:2389	chitosan	2382:2389	chitosan	2382:2389	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	1	14	theme	tensile	196:202	arg1	BS					204:205	the tensile BS	192:205	the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	192:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	15	15	theme	materials	2198:2206	arg1	strength					2168:2175	bond strength	2163:2175	bond strength of the luting dental materials (p ≤ 0.05)	2163:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	14	16	theme	lowest	2052:2057	arg1	strength					2064:2071	lowest bond strength	2052:2071	statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31)	2015:2089	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	14	16	theme	lowest	2052:2057	arg1	±					2083:2083	276.62 N ± 4.31	2074:2088	276.62 N ± 4.31	2074:2088	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	16	17	dep	GIC	2431:2433	arg1	contrast					2406:2413	contrast	2406:2413	contrast	2406:2413	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	13	18	theme	self-adhesive	1841:1853	arg1	resin					1855:1859	self-adhesive resin	1841:1859	self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1841:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	1	19	dep	conventional	225:236	arg1	cement					275:280	modified GIC cement	262:280	modified GIC cement	262:280	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	7	20	theme	peso	1334:1337	arg1	reamers					1339:1345	peso reamers	1334:1345	peso reamers	1334:1345	After incubation for seven days in an environment mimicking oral cavity, post space was created using peso reamers.					
35856349	11	21	theme	bond	1656:1659	arg1	fracture/failure					1661:1676	bond fracture/failure	1656:1676	bond fracture/failure	1656:1676	The type of bond fracture/failure was evaluated under 30x magnification.					
35856349	0	22	theme	different	58:66	arg1	luting					68:73	different luting	58:73	different luting	58:73	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	1	23	theme	radicular	312:320	arg1	dentin					322:327	post-space radicular dentin	301:327	post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	301:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	8	24	dep	chitosan	1381:1388	arg1	mg/mL					1392:1396	3 mg/mL	1390:1396	G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6	1377:1429	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	2	25	theme	specific	496:503	arg1	criteria					525:532	specific exclusion/inclusion criteria	496:532	specific exclusion/inclusion criteria	496:532	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	5	26	theme	rotary	942:947	arg1	UK					989:990	UK	989:990	UK	989:990	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	5	26	theme	rotary	942:947	arg1	NiTi					949:952	Next rotary NiTi	937:952	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl	928:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	2	27	theme	thorough	546:553	arg1	debridement					555:565	thorough debridement	546:565	thorough debridement of plaque/calculus	546:584	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	14	28	theme	≤	2044:2044	arg1	p					2042:2042	p ≤ 0.05	2042:2049	p ≤ 0.05	2042:2049	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	4	29	theme	samples	777:783	arg1	region					763:768	The radicular region	749:768	The radicular region of the samples	749:783	The radicular region of the samples was entrenched perpendicularly in heat cure resin modified acrylic.					
35856349	1	30	theme	photo-activated	342:356	arg1	photosensitizer					358:372	various photo-activated photosensitizer	334:372	various photo-activated photosensitizer (chitosan, TB and Clp6)	334:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	4	31	theme	heat	819:822	arg1	resin					829:833	heat cure resin	819:833	heat cure resin modified acrylic	819:850	The radicular region of the samples was entrenched perpendicularly in heat cure resin modified acrylic.					
35856349	5	32	theme	continuous	1005:1014	arg1	irrigation					1016:1025	continuous irrigation	1005:1025	continuous irrigation with NaOCl	1005:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	2	33	theme	extracted	447:455	arg1	pre-molars					468:477	Sixty-six orthodontically extracted mandibular pre-molars	421:477	Sixty-six orthodontically extracted mandibular pre-molars	421:477	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	16	34	theme	&	2395:2395	arg1	Clp6					2397:2400	TB & Clp6	2392:2400	TB & Clp6	2392:2400	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	16	34	theme	&	2395:2395	arg1	chitosan					2382:2389	chitosan	2382:2389	chitosan	2382:2389	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	15	35	theme	dental	2191:2196	arg1	p					2209:2209	p ≤ 0.05	2209:2216	p ≤ 0.05	2209:2216	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	15	35	theme	dental	2191:2196	arg1	materials					2198:2206	the luting dental materials	2180:2206	the luting dental materials (p ≤ 0.05)	2180:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	0	36	dep	cements	75:81	arg1	used					83:86	used	83:86	cements used for cementation of resin modified composite fiber posts	75:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	15	37	from	difference	2149:2158	arg1	strength					2168:2175	bond strength	2163:2175	bond strength of the luting dental materials (p ≤ 0.05)	2163:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	10	38	theme	prior	1615:1619	arg1	hrs					1611:1613	48 hrs	1608:1613	48 hrs prior to tensile BS testing	1608:1641	The specimens were incubated for 48 hrs prior to tensile BS testing.					
35856349	0	39	theme	photosensitizers	10:25	arg1	Effect					0:5	Effect	0:5	Effect of photosensitizers on modulating bond strength of different luting	0:73	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	1	40	theme	GIC	271:273	arg1	cement					275:280	modified GIC cement	262:280	modified GIC cement	262:280	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	7	41	theme	post	1305:1308	arg1	space					1310:1314	post space	1305:1314	post space	1305:1314	After incubation for seven days in an environment mimicking oral cavity, post space was created using peso reamers.					
35856349	6	42	theme	paper	1067:1071	arg1	points					1073:1078	paper points	1067:1078	paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1067:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	12	43	theme	respective	1798:1807	arg1	groups					1809:1814	respective groups	1798:1814	respective groups	1798:1814	The tensile BS was statistically analyzed using ANOVA trailed by Tukey's test to respective groups.					
35856349	3	44	theme	selected	667:674	arg1	teeth					676:680	The selected teeth	663:680	The selected teeth	663:680	The selected teeth were sectioned from the cement-enamel junction removing the crown.					
35856349	1	45	dep	photosensitizer	358:372	arg1	Clp6					392:395	Clp6	392:395	Clp6	392:395	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	1	45	dep	photosensitizer	358:372	arg1	TB					385:386	TB	385:386	TB	385:386	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	1	45	dep	photosensitizer	358:372	arg1	chitosan					375:382	chitosan	375:382	chitosan	375:382	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	3	46	theme	cement-enamel	706:718	arg1	junction					720:727	the cement-enamel junction	702:727	the cement-enamel junction removing the crown	702:746	The selected teeth were sectioned from the cement-enamel junction removing the crown.					
35856349	10	47	theme	tensile	1624:1630	arg1	testing					1635:1641	tensile BS testing	1624:1641	tensile BS testing	1624:1641	The specimens were incubated for 48 hrs prior to tensile BS testing.					
35856349	16	48	dep	CONCLUSIONS	2220:2230	arg1	revealed					2272:2279	revealed	2272:2279	revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC	2272:2433	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	12	49	theme	tensile	1721:1727	arg1	BS					1729:1730	The tensile BS	1717:1730	The tensile BS	1717:1730	The tensile BS was statistically analyzed using ANOVA trailed by Tukey's test to respective groups.					
35856349	5	50	theme	ProTaper	928:935	arg1	files					993:997	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files	928:997	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl	928:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	13	51	theme	tensile	1929:1935	arg1	BS					1937:1938	highest tensile BS	1921:1938	highest tensile BS	1921:1938	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	1	52	theme	FPs	210:212	arg1	BS					204:205	the tensile BS	192:205	the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	192:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	6	53	theme	Obturators	1120:1129	arg1	UK					1162:1163	UK	1162:1163	UK	1162:1163	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	53	theme	Obturators	1120:1129	arg1	points					1144:1149	Pro Taper Next Obturators gutta-percha points	1105:1149	Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1105:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	5	54	with	irrigation	1016:1025	arg1	NaOCl					1032:1036	NaOCl	1032:1036	NaOCl	1032:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	13	55	theme	291.47	1940:1945	arg1	±					1949:1949	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	15	56	theme	≤	2211:2211	arg1	p					2209:2209	p ≤ 0.05	2209:2216	p ≤ 0.05	2209:2216	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	15	56	theme	≤	2211:2211	arg1	materials					2198:2206	the luting dental materials	2180:2206	the luting dental materials (p ≤ 0.05)	2180:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	16	57	theme	TB	2392:2393	arg1	Clp6					2397:2400	TB & Clp6	2392:2400	TB & Clp6	2392:2400	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	16	57	theme	TB	2392:2393	arg1	chitosan					2382:2389	chitosan	2382:2389	chitosan	2382:2389	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	7	58	from	incubation	1238:1247	arg1	environment					1270:1280	an environment	1267:1280	an environment mimicking oral cavity	1267:1302	After incubation for seven days in an environment mimicking oral cavity, post space was created using peso reamers.					
35856349	6	59	theme	Taper	1109:1113	arg1	UK					1162:1163	UK	1162:1163	UK	1162:1163	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	59	theme	Taper	1109:1113	arg1	points					1144:1149	Pro Taper Next Obturators gutta-percha points	1105:1149	Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1105:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	16	60	theme	self-adhesive	2236:2248	arg1	cement					2265:2270	The self-adhesive resin modified cement	2232:2270	The self-adhesive resin modified cement	2232:2270	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	2	61	theme	Chloramine	618:627	arg1	T					629:629	Chloramine T	618:629	Chloramine T	618:629	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	2	62	from	immersion	605:613	arg1	T					629:629	Chloramine T	618:629	Chloramine T	618:629	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	16	63	theme	modified	2256:2263	arg1	cement					2265:2270	The self-adhesive resin modified cement	2232:2270	The self-adhesive resin modified cement	2232:2270	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	1	64	theme	study	170:174	arg1	aim					159:161	The aim	155:161	The aim of the study	155:174	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	13	65	dep	FPs	1825:1827	arg1	luted					1829:1833	luted	1829:1833	FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1825:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	5	66	theme	canal	909:913	arg1	shaping					915:921	canal shaping	909:921	canal shaping	909:921	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	14	67	theme	N	2081:2081	arg1	strength					2064:2071	lowest bond strength	2052:2071	statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31)	2015:2089	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	14	67	theme	N	2081:2081	arg1	±					2083:2083	276.62 N ± 4.31	2074:2088	276.62 N ± 4.31	2074:2088	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	0	68	theme	composite	122:130	arg1	posts					138:142	resin modified composite fiber posts	107:142	resin modified composite fiber posts	107:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	16	69	theme	bond	2288:2291	arg1	strength					2293:2300	utmost bond strength	2281:2300	utmost bond strength	2281:2300	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	2	70	theme	plaque/calculus	570:584	arg1	debridement					555:565	thorough debridement	546:565	thorough debridement of plaque/calculus	546:584	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	8	71	theme	mg/mL	1409:1413	arg1	TB					1415:1416	13-15 mg/mL TB	1403:1416	13-15 mg/mL TB	1403:1416	The space was disinfected by G1: chitosan 3 mg/mL; G2: 13-15 mg/mL TB and G3: Clp6.					
35856349	9	72	theme	conventional	1479:1490	arg1	n=11					1540:1543	n=11	1540:1543	n=11	1540:1543	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	9	72	theme	conventional	1479:1490	arg1	cement					1532:1537	conventional (n=11) and resin modified self-adhesive cement	1479:1537	conventional (n=11) and resin modified self-adhesive cement (n=11)	1479:1544	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	6	73	dep	ADSEAL	1178:1183	arg1	Meta					1186:1189	Meta	1186:1189	Meta Biomed, Chungcheongbuk-do, South Korea	1186:1228	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	0	74	theme	posts	138:142	arg1	cementation					92:102	cementation	92:102	cementation of resin modified composite fiber posts	92:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	14	75	dep	significant	2029:2039	arg1	p					2042:2042	p ≤ 0.05	2042:2049	p ≤ 0.05	2042:2049	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	6	76	dep	Meta	1186:1189	arg1	South					1218:1222	South	1218:1222	South	1218:1222	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	76	dep	Meta	1186:1189	arg1	Chungcheongbuk-do					1199:1215	Chungcheongbuk-do	1199:1215	Chungcheongbuk-do	1199:1215	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	76	dep	Meta	1186:1189	arg1	Korea					1224:1228	Korea	1224:1228	Korea	1224:1228	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	14	77	theme	bond	2059:2062	arg1	strength					2064:2071	lowest bond strength	2052:2071	statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31)	2015:2089	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	14	77	theme	bond	2059:2062	arg1	±					2083:2083	276.62 N ± 4.31	2074:2088	276.62 N ± 4.31	2074:2088	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	5	78	theme	NiTi	949:952	arg1	files					993:997	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files	928:997	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl	928:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	4	79	theme	radicular	753:761	arg1	region					763:768	The radicular region	749:768	The radicular region of the samples	749:783	The radicular region of the samples was entrenched perpendicularly in heat cure resin modified acrylic.					
35856349	0	80	theme	luting	68:73	arg1	strength					46:53	bond strength	41:53	bond strength of different luting	41:73	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	15	81	theme	Intra-group	2092:2102	arg1	analysis					2104:2111	Intra-group analysis	2092:2111	Intra-group analysis	2092:2111	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	2	82	theme	exclusion/inclusion	505:523	arg1	criteria					525:532	specific exclusion/inclusion criteria	496:532	specific exclusion/inclusion criteria	496:532	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	11	83	theme	fracture/failure	1661:1676	arg1	type					1648:1651	The type	1644:1651	The type of bond fracture/failure	1644:1676	The type of bond fracture/failure was evaluated under 30x magnification.					
35856349	1	84	theme	dentin	322:327	arg1	disinfection					285:296	disinfection	285:296	disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	285:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	5	85	theme	Next	937:940	arg1	UK					989:990	UK	989:990	UK	989:990	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	5	85	theme	Next	937:940	arg1	NiTi					949:952	Next rotary NiTi	937:952	ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl	928:1036	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	1	86	theme	various	334:340	arg1	photosensitizer					358:372	various photo-activated photosensitizer	334:372	various photo-activated photosensitizer (chitosan, TB and Clp6)	334:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	1	87	with	dentin	322:327	arg1	photosensitizer					358:372	various photo-activated photosensitizer	334:372	various photo-activated photosensitizer (chitosan, TB and Clp6)	334:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	16	88	theme	respective	2338:2347	arg1	photosensitizer					2365:2379	respective photo-activated photosensitizer	2338:2379	respective photo-activated photosensitizer (chitosan, TB & Clp6)	2338:2401	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	0	89	theme	resin	107:111	arg1	posts					138:142	resin modified composite fiber posts	107:142	resin modified composite fiber posts	107:142	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	6	90	theme	Pro	1105:1107	arg1	UK					1162:1163	UK	1162:1163	UK	1162:1163	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	90	theme	Pro	1105:1107	arg1	points					1144:1149	Pro Taper Next Obturators gutta-percha points	1105:1149	Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1105:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	14	91	theme	significant	2029:2039	arg1	strength					2064:2071	lowest bond strength	2052:2071	statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31)	2015:2089	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	14	91	theme	significant	2029:2039	arg1	±					2083:2083	276.62 N ± 4.31	2074:2088	276.62 N ± 4.31	2074:2088	On the contrary, post-space disinfected by Clp6 displayed statistically significant (p ≤ 0.05) lowest bond strength (276.62 N ± 4.31).					
35856349	9	92	theme	resin	1503:1507	arg1	n=11					1540:1543	n=11	1540:1543	n=11	1540:1543	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	9	92	theme	resin	1503:1507	arg1	cement					1532:1537	conventional (n=11) and resin modified self-adhesive cement	1479:1537	conventional (n=11) and resin modified self-adhesive cement (n=11)	1479:1544	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	15	93	theme	bond	2163:2166	arg1	strength					2168:2175	bond strength	2163:2175	bond strength of the luting dental materials (p ≤ 0.05)	2163:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	9	94	dep	conventional	1479:1490	arg1	n=11					1493:1496	n=11	1493:1496	n=11	1493:1496	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	5	95	theme	pulpal	857:862	arg1	tissue					864:869	The pulpal tissue	853:869	The pulpal tissue	853:869	The pulpal tissue was detached using K-files trailed by canal shaping with ProTaper Next rotary NiTi (Dentsply Sirona, Gloucestershire, UK) files under continuous irrigation with NaOCl.					
35856349	1	96	theme	modified	262:269	arg1	cement					275:280	modified GIC cement	262:280	modified GIC cement	262:280	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	9	97	theme	self-adhesive	1518:1530	arg1	n=11					1540:1543	n=11	1540:1543	n=11	1540:1543	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	9	97	theme	self-adhesive	1518:1530	arg1	cement					1532:1537	conventional (n=11) and resin modified self-adhesive cement	1479:1537	conventional (n=11) and resin modified self-adhesive cement (n=11)	1479:1544	After photo-irridation the FPs were luted with conventional (n=11) and resin modified self-adhesive cement (n=11) for each group respectively.					
35856349	13	98	with	cement	1870:1875	arg1	±					1949:1949	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	1	99	dep	OBJECTIVE	145:153	arg1	was					176:178	was	176:178	was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	176:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	0	100	theme	bond	41:44	arg1	strength					46:53	bond strength	41:53	bond strength of different luting	41:73	Effect of photosensitizers on modulating bond strength of different luting cements used for cementation of resin modified composite fiber posts.					
35856349	15	101	theme	luting	2184:2189	arg1	p					2209:2209	p ≤ 0.05	2209:2216	p ≤ 0.05	2209:2216	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	15	101	theme	luting	2184:2189	arg1	materials					2198:2206	the luting dental materials	2180:2206	the luting dental materials (p ≤ 0.05)	2180:2217	Intra-group analysis displayed statistically significant difference in bond strength of the luting dental materials (p ≤ 0.05).					
35856349	7	102	theme	oral	1292:1295	arg1	cavity					1297:1302	oral cavity	1292:1302	oral cavity	1292:1302	After incubation for seven days in an environment mimicking oral cavity, post space was created using peso reamers.					
35856349	13	103	theme	N	1947:1947	arg1	±					1949:1949	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36	1882:1954	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	16	104	theme	conventional	2418:2429	arg1	GIC					2431:2433	conventional GIC	2418:2433	conventional GIC	2418:2433	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	2	105	theme	mandibular	457:466	arg1	pre-molars					468:477	Sixty-six orthodontically extracted mandibular pre-molars	421:477	Sixty-six orthodontically extracted mandibular pre-molars	421:477	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	2	106	dep	MATERIALS	399:407	arg1	trailed					535:541	trailed	535:541	trailed by thorough debridement of plaque/calculus	535:584	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	2	106	dep	MATERIALS	399:407	arg1	disinfected					590:600	disinfected	590:600	disinfected by immersion in Chloramine T	590:629	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	2	106	dep	MATERIALS	399:407	arg1	selected					484:491	selected	484:491	selected on specific exclusion/inclusion criteria	484:532	MATERIALS AND METHODS Sixty-six orthodontically extracted mandibular pre-molars were selected on specific exclusion/inclusion criteria, trailed by thorough debridement of plaque/calculus and disinfected by immersion in Chloramine T trihydrate solution for 48 hrs.					
35856349	16	107	theme	post-space	2322:2331	arg1	pre-treatment					2305:2317	pre-treatment	2305:2317	pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6)	2305:2401	CONCLUSIONS The self-adhesive resin modified cement revealed utmost bond strength on pre-treatment of post-space with respective photo-activated photosensitizer (chitosan, TB & Clp6) in contrast to conventional GIC.					
35856349	10	108	theme	BS	1632:1633	arg1	testing					1635:1641	tensile BS testing	1624:1641	tensile BS testing	1624:1641	The specimens were incubated for 48 hrs prior to tensile BS testing.					
35856349	1	109	theme	post-space	301:310	arg1	dentin					322:327	post-space radicular dentin	301:327	post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6)	301:396	OBJECTIVE The aim of the study was to evaluate the tensile BS of FPs luted with conventional and self-adhesive resin modified GIC cement on disinfection of post-space radicular dentin with various photo-activated photosensitizer (chitosan, TB and Clp6).					
35856349	4	110	theme	cure	824:827	arg1	resin					829:833	heat cure resin	819:833	heat cure resin modified acrylic	819:850	The radicular region of the samples was entrenched perpendicularly in heat cure resin modified acrylic.					
35856349	13	111	theme	highest	1921:1927	arg1	BS					1937:1938	highest tensile BS	1921:1938	highest tensile BS	1921:1938	RESULTS FPs luted using self-adhesive resin modified cement with prior to disinfection by TBs displayed highest tensile BS 291.47 N ± 5.36.					
35856349	6	112	theme	gutta-percha	1131:1142	arg1	UK					1162:1163	UK	1162:1163	UK	1162:1163	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
35856349	6	112	theme	gutta-percha	1131:1142	arg1	points					1144:1149	Pro Taper Next Obturators gutta-percha points	1105:1149	Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea)	1105:1229	The canals were dried using paper points trailed by obturation by Pro Taper Next Obturators gutta-percha points (Dentsply, UK) coated with ADSEAL (Meta Biomed, Chungcheongbuk-do, South Korea).					
34995607	7	0	contain	had	1182:1184	arg2	prospect					1198:1205	application prospect	1186:1205	application prospect	1186:1205	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	7	0	contain	had	1182:1184	arg1	membrane					1173:1180	The prepared composite membrane	1150:1180	The prepared composite membrane	1150:1180	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	6	1	from	decrease	1004:1011	arg1	strength					1024:1031	tensile strength	1016:1031	tensile strength	1016:1031	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	1	from	decrease	1004:1011	arg1	retention					1041:1049	the retention	1037:1049	the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles	1037:1147	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	5	2	theme	characteristic	825:838	arg1	leachable					859:867	the toxicity characteristic leaching procedure leachable	812:867	the toxicity characteristic leaching procedure leachable	812:867	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	1	3	theme	arsenic	188:194	arg1	matter					239:244	a matter	237:244	a matter of great concern	237:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	3	theme	arsenic	188:194	arg1	removal					177:183	Simultaneous removal	164:183	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil	164:226	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	0	4	theme	simultaneous	109:120	arg1	removal					122:128	simultaneous removal	109:128	simultaneous removal of arsenic and cadmium from soil	109:161	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	7	5	theme	application	1186:1196	arg1	prospect					1198:1205	application prospect	1186:1205	application prospect	1186:1205	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	0	6	theme	arsenic	133:139	arg1	removal					122:128	simultaneous removal	109:128	simultaneous removal of arsenic and cadmium from soil	109:161	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	7	7	theme	co-polluted	1239:1249	arg1	soil					1251:1254	As and Cd co-polluted soil	1229:1254	As and Cd co-polluted soil	1229:1254	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	7	8	theme	soil	1251:1254	arg1	remediation					1214:1224	the remediation	1210:1224	the remediation of As and Cd co-polluted soil	1210:1254	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	1	9	theme	great	249:253	arg1	concern					255:261	great concern	249:261	great concern	249:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	10	dep	arsenic	188:194	arg1	As					197:198	As	197:198	As	197:198	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	2	11	theme	loading	374:380	arg1	ferrihydrite					398:409	loading manganese-doped ferrihydrite	374:409	loading manganese-doped ferrihydrite on cellulose mesh	374:427	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	1	12	theme	concern	255:261	arg1	removal					177:183	Simultaneous removal	164:183	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil	164:226	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	12	theme	concern	255:261	arg1	matter					239:244	a matter	237:244	a matter of great concern	237:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	0	13	theme	cadmium	145:151	arg1	removal					122:128	simultaneous removal	109:128	simultaneous removal of arsenic and cadmium from soil	109:161	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	6	14	theme	%	1064:1064	arg1	strength					1024:1031	tensile strength	1016:1031	tensile strength	1016:1031	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	14	theme	%	1064:1064	arg1	retention					1041:1049	the retention	1037:1049	the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles	1037:1147	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	5	15	theme	leaching	840:847	arg1	leachable					859:867	the toxicity characteristic leaching procedure leachable	812:867	the toxicity characteristic leaching procedure leachable	812:867	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	6	16	theme	membrane	971:978	arg1	reusability					946:956	reusability	946:956	reusability	946:956	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	16	theme	membrane	971:978	arg1	stability					932:940	stability	932:940	stability	932:940	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	2	17	theme	composite	336:344	arg1	membranes					346:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	3	18	theme	obtained	475:482	arg1	membranes					494:502	The obtained composite membranes	471:502	The obtained composite membranes	471:502	The obtained composite membranes exhibited excellent mechanical properties and could be easily separated from soil.					
34995607	0	19	theme	ferrihydrite/cellulose/polyvinyl	16:47	arg1	membrane					67:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane	0:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.	0:162	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	7	20	theme	prepared	1154:1161	arg1	membrane					1173:1180	The prepared composite membrane	1150:1180	The prepared composite membrane	1150:1180	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	2	21	theme	alcohol	328:334	arg1	membranes					346:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	2	22	theme	cellulose	414:422	arg1	mesh					424:427	cellulose mesh	414:427	cellulose mesh	414:427	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	0	23	theme	Manganese-doped	0:14	arg1	membrane					67:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane	0:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.	0:162	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	6	24	theme	composite	961:969	arg1	membrane					971:978	composite membrane	961:978	composite membrane	961:978	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	2	25	from	ferrihydrite	398:409	arg1	mesh					424:427	cellulose mesh	414:427	cellulose mesh	414:427	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	2	26	theme	ferrihydrite/cellulose/polyvinyl	295:326	arg1	membranes					346:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	1	27	theme	cadmium	205:211	arg1	matter					239:244	a matter	237:244	a matter of great concern	237:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	27	theme	cadmium	205:211	arg1	removal					177:183	Simultaneous removal	164:183	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil	164:226	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	0	28	theme	composite	57:65	arg1	membrane					67:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane	0:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.	0:162	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	5	29	theme	composite	723:731	arg1	membrane					733:740	the composite membrane	719:740	the composite membrane	719:740	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	2	30	theme	manganese-doped	279:293	arg1	membranes					346:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes	279:354	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	2	31	theme	polyvinyl	452:460	arg1	alcohol					462:468	polyvinyl alcohol	452:468	polyvinyl alcohol	452:468	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
34995607	0	32	theme	alcohol	49:55	arg1	membrane					67:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane	0:74	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.	0:162	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	5	33	from	dosage	764:769	arg1	soil					756:759	polluted soil	747:759	polluted soil at dosage of 0.3% (w/w)	747:783	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	6	34	theme	Cd	1081:1082	arg1	III					1072:1074	III	1072:1074	III	1072:1074	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	34	theme	Cd	1081:1082	arg1	Cd					1081:1082	Cd(II)	1081:1086	Cd(II)	1081:1086	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	34	theme	Cd	1081:1082	arg1	As					1069:1070	As	1069:1070	As	1069:1070	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	34	theme	Cd	1081:1082	arg1	%					1056:1056	94%	1054:1056	94%	1054:1056	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	34	theme	Cd	1081:1082	arg1	%					1064:1064	96%	1062:1064	96% of As(III) and Cd(II) removal efficiency	1062:1105	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	3	35	theme	excellent	514:522	arg1	properties					535:544	excellent mechanical properties	514:544	excellent mechanical properties	514:544	The obtained composite membranes exhibited excellent mechanical properties and could be easily separated from soil.					
34995607	4	36	theme	Cd	616:617	arg1	11.11 mg/g					666:675	11.11 mg/g	666:675	11.11 mg/g	666:675	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	4	36	theme	Cd	616:617	arg1	capacities					602:611	The adsorption capacities	587:611	The adsorption capacities of Cd(II) and As(III) on the composite membrane	587:659	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	5	37	theme	procedure	849:857	arg1	leachable					859:867	the toxicity characteristic leaching procedure leachable	812:867	the toxicity characteristic leaching procedure leachable	812:867	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	3	38	theme	composite	484:492	arg1	membranes					494:502	The obtained composite membranes	471:502	The obtained composite membranes	471:502	The obtained composite membranes exhibited excellent mechanical properties and could be easily separated from soil.					
34995607	5	39	theme	polluted	747:754	arg1	soil					756:759	polluted soil	747:759	polluted soil at dosage of 0.3% (w/w)	747:783	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	6	40	dep	stability	932:940	arg1	The					928:930	The	928:930	The	928:930	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	5	41	theme	leachable	859:867	arg1	efficiency					798:807	the removal efficiency	786:807	the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd	786:877	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	5	42	theme	%	777:777	arg1	dosage					764:769	dosage	764:769	dosage of 0.3% (w/w)	764:783	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	6	43	dep	As	1069:1070	arg1	efficiency					1096:1105	removal efficiency	1088:1105	removal efficiency	1088:1105	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	5	44	theme	removal	790:796	arg1	efficiency					798:807	the removal efficiency	786:807	the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd	786:877	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	4	45	theme	adsorption	591:600	arg1	11.11 mg/g					666:675	11.11 mg/g	666:675	11.11 mg/g	666:675	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	4	45	theme	adsorption	591:600	arg1	capacities					602:611	The adsorption capacities	587:611	The adsorption capacities of Cd(II) and As(III) on the composite membrane	587:659	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	0	46	dep	membrane	67:74	arg1	adsorbent					95:103	adsorbent	95:103	adsorbent	95:103	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	7	47	theme	As	1229:1230	arg1	soil					1251:1254	As and Cd co-polluted soil	1229:1254	As and Cd co-polluted soil	1229:1254	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	1	48	from	soil	223:226	arg1	matter					239:244	a matter	237:244	a matter of great concern	237:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	48	from	soil	223:226	arg1	removal					177:183	Simultaneous removal	164:183	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil	164:226	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	3	49	theme	mechanical	524:533	arg1	properties					535:544	excellent mechanical properties	514:544	excellent mechanical properties	514:544	The obtained composite membranes exhibited excellent mechanical properties and could be easily separated from soil.					
34995607	6	50	theme	tensile	1016:1022	arg1	strength					1024:1031	tensile strength	1016:1031	tensile strength	1016:1031	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	51	theme	removal	1088:1094	arg1	efficiency					1096:1105	removal efficiency	1088:1105	removal efficiency	1088:1105	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	5	52	theme	toxicity	816:823	arg1	leachable					859:867	the toxicity characteristic leaching procedure leachable	812:867	the toxicity characteristic leaching procedure leachable	812:867	After mixing the composite membrane with polluted soil at dosage of 0.3% (w/w), the removal efficiency of the toxicity characteristic leaching procedure leachable As and Cd reached 65% and 69% respectively with one cycle.					
34995607	1	53	theme	Simultaneous	164:175	arg1	matter					239:244	a matter	237:244	a matter of great concern	237:261	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	1	53	theme	Simultaneous	164:175	arg1	removal					177:183	Simultaneous removal	164:183	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil	164:226	Simultaneous removal of arsenic (As) and cadmium (Cd) from soil has been a matter of great concern.					
34995607	7	54	theme	composite	1163:1171	arg1	membrane					1173:1180	The prepared composite membrane	1150:1180	The prepared composite membrane	1150:1180	The prepared composite membrane had application prospect in the remediation of As and Cd co-polluted soil.					
34995607	6	55	theme	adsorption	1131:1140	arg1	cycles					1142:1147	four adsorption cycles	1126:1147	four adsorption cycles	1126:1147	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	4	56	theme	composite	642:650	arg1	membrane					652:659	the composite membrane	638:659	the composite membrane	638:659	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	6	57	theme	As	1069:1070	arg1	III					1072:1074	III	1072:1074	III	1072:1074	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	57	theme	As	1069:1070	arg1	Cd					1081:1082	Cd(II)	1081:1086	Cd(II)	1081:1086	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	57	theme	As	1069:1070	arg1	As					1069:1070	As	1069:1070	As	1069:1070	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	57	theme	As	1069:1070	arg1	%					1056:1056	94%	1054:1056	94%	1054:1056	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	57	theme	As	1069:1070	arg1	%					1064:1064	96%	1062:1064	96% of As(III) and Cd(II) removal efficiency	1062:1105	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	58	theme	%	1056:1056	arg1	strength					1024:1031	tensile strength	1016:1031	tensile strength	1016:1031	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	6	58	theme	%	1056:1056	arg1	retention					1041:1049	the retention	1037:1049	the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles	1037:1147	The stability and reusability of composite membrane were demonstrated by no decrease in tensile strength and the retention of 94% and 96% of As(III) and Cd(II) removal efficiency respectively after four adsorption cycles.					
34995607	0	59	from	soil	158:161	arg1	removal					122:128	simultaneous removal	109:128	simultaneous removal of arsenic and cadmium from soil	109:161	Manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membrane: Easily recyclable adsorbent for simultaneous removal of arsenic and cadmium from soil.					
34995607	4	60	theme	As	627:628	arg1	11.11 mg/g					666:675	11.11 mg/g	666:675	11.11 mg/g	666:675	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	4	60	theme	As	627:628	arg1	capacities					602:611	The adsorption capacities	587:611	The adsorption capacities of Cd(II) and As(III) on the composite membrane	587:659	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	4	61	from	capacities	602:611	arg1	membrane					652:659	the composite membrane	638:659	the composite membrane	638:659	The adsorption capacities of Cd(II) and As(III) on the composite membrane were 11.11 mg/g and 72.08 mg/g respectively.					
34995607	2	62	theme	manganese-doped	382:396	arg1	ferrihydrite					398:409	loading manganese-doped ferrihydrite	374:409	loading manganese-doped ferrihydrite on cellulose mesh	374:427	In this study, manganese-doped ferrihydrite/cellulose/polyvinyl alcohol composite membranes were prepared via loading manganese-doped ferrihydrite on cellulose mesh and then wrapping with polyvinyl alcohol.					
36758760	0	0	theme	enhanced	85:92	arg1	proliferation					112:124	enhanced adipose stem cell proliferation	85:124	enhanced adipose stem cell proliferation	85:124	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	8	1	theme	scaffolds	1452:1460	arg1	analysis					1427:1434	SEM analysis	1423:1434	SEM analysis of ADSCs seeded scaffolds	1423:1460	Fluorescence PKH26 stained images and SEM analysis of ADSCs seeded scaffolds revealed biocompatible nature.					
36758760	3	2	theme	zinc	547:550	arg1	nanoparticles					558:570	zinc oxide nanoparticles	547:570	zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	547:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	5	3	theme	Fabricated	951:960	arg1	gels					962:965	Fabricated gels	951:965	Fabricated gels	951:965	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	4	4	dep	spectroscopy	893:904	arg1	analysis					941:948	analysis	941:948	analysis	941:948	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	5	5	theme	controlled	1055:1064	arg1	kinetics					1074:1081	controlled release kinetics	1055:1081	controlled release kinetics of ZnO-NPs	1055:1092	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	2	6	theme	composite	385:393	arg1	scaffold					395:402	a porous hydrogel composite scaffold	367:402	a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds	367:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	8	7	theme	biocompatible	1471:1483	arg1	nature					1485:1490	biocompatible nature	1471:1490	biocompatible nature	1471:1490	Fluorescence PKH26 stained images and SEM analysis of ADSCs seeded scaffolds revealed biocompatible nature.					
36758760	0	8	theme	stem	102:105	arg1	proliferation					112:124	enhanced adipose stem cell proliferation	85:124	enhanced adipose stem cell proliferation	85:124	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	6	9	dep	In	1095:1096	arg1	vitro					1098:1102	vitro	1098:1102	vitro	1098:1102	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	10	theme	MTT	1198:1200	arg1	assay					1234:1238	MTT and lactate dehydrogenase (LDH) assay	1198:1238	MTT and lactate dehydrogenase (LDH) assay	1198:1238	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	2	11	dep	scaffold	395:402	arg1	alginate					422:429	sodium alginate	415:429	sodium alginate	415:429	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	2	11	dep	scaffold	395:402	arg1	elastin					435:441	elastin	435:441	elastin	435:441	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	2	11	dep	scaffold	395:402	arg1	chitosan					405:412	chitosan	405:412	chitosan	405:412	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	7	12	theme	ZnO-NPs	1355:1361	arg1	loading					1344:1350	the successful loading	1329:1350	the successful loading of ZnO-NPs into these scaffolds	1329:1382	The SEM and XRD analysis confirmed the successful loading of ZnO-NPs into these scaffolds.					
36758760	1	13	theme	cellular	288:295	arg1	attachment					297:306	cellular attachment	288:306	cellular attachment	288:306	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	0	14	theme	adipose	94:100	arg1	proliferation					112:124	enhanced adipose stem cell proliferation	85:124	enhanced adipose stem cell proliferation	85:124	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	0	15	with	gel	76:78	arg1	properties					144:153	antibacterial properties	130:153	antibacterial properties	130:153	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	0	15	with	gel	76:78	arg1	proliferation					112:124	enhanced adipose stem cell proliferation	85:124	enhanced adipose stem cell proliferation	85:124	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	6	16	theme	adipose	1168:1174	arg1	ADSCs					1188:1192	ADSCs	1188:1192	ADSCs	1188:1192	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	16	theme	adipose	1168:1174	arg1	cells					1181:1185	human adipose stem cells	1162:1185	human adipose stem cells (ADSCs)	1162:1193	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	17	theme	In	1095:1096	arg1	cytocompatibility					1104:1120	In vitro cytocompatibility	1095:1120	In vitro cytocompatibility of the composite	1095:1137	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	9	18	contain	have	1550:1553	arg2	potential					1555:1563	potential	1555:1563	potential	1555:1563	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	9	18	contain	have	1550:1553	arg1	gels					1545:1548	the developed composite gels	1521:1548	the developed composite gels	1521:1548	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	3	19	dep	ZnO-NPs	577:583	arg1	i.e.					572:575	i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w)	572:617	zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	547:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	7	20	theme	successful	1333:1342	arg1	loading					1344:1350	the successful loading	1329:1350	the successful loading of ZnO-NPs into these scaffolds	1329:1382	The SEM and XRD analysis confirmed the successful loading of ZnO-NPs into these scaffolds.					
36758760	6	21	theme	human	1162:1166	arg1	ADSCs					1188:1192	ADSCs	1188:1192	ADSCs	1188:1192	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	21	theme	human	1162:1166	arg1	cells					1181:1185	human adipose stem cells	1162:1185	human adipose stem cells (ADSCs)	1162:1193	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	1	22	theme	choice	192:197	arg1	material					180:187	the material	176:187	the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation	176:324	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	1	22	theme	choice	192:197	arg1	Hydrogels					156:164	Hydrogels	156:164	Hydrogels	156:164	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	0	23	theme	cell	107:110	arg1	proliferation					112:124	enhanced adipose stem cell proliferation	85:124	enhanced adipose stem cell proliferation	85:124	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	analysis					993:1000	SEM analysis	989:1000	SEM analysis	989:1000	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	ratio					1023:1027	swelling ratio	1014:1027	swelling ratio	1014:1027	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	kinetics					1074:1081	controlled release kinetics	1055:1081	controlled release kinetics of ZnO-NPs	1055:1092	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	FTIR					1003:1006	FTIR	1003:1006	FTIR	1003:1006	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	XRD					1009:1011	XRD	1009:1011	XRD	1009:1011	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	5	24	theme	ZnO-NPs	1086:1092	arg1	behavior					1042:1049	degradation behavior	1030:1049	degradation behavior	1030:1049	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	9	25	theme	wound	1611:1615	arg1	treatment					1617:1625	chronic wound treatment	1603:1625	chronic wound treatment	1603:1625	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	2	26	theme	chronic	462:468	arg1	wounds					475:480	chronic skin wounds	462:480	chronic skin wounds	462:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	2	27	theme	skin	470:473	arg1	wounds					475:480	chronic skin wounds	462:480	chronic skin wounds	462:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	2	28	theme	sodium	415:420	arg1	alginate					422:429	sodium alginate	415:429	sodium alginate	415:429	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	0	29	theme	Freeze	0:5	arg1	oxide					56:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	3	30	theme	antibacterial	740:752	arg1	activities					754:763	good antibacterial activities	735:763	good antibacterial activities	735:763	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	6	31	theme	dehydrogenase	1214:1226	arg1	assay					1234:1238	MTT and lactate dehydrogenase (LDH) assay	1198:1238	MTT and lactate dehydrogenase (LDH) assay	1198:1238	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	0	32	theme	/zinc	50:54	arg1	oxide					56:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	0	33	theme	chitosan-elastin‑sodium	17:39	arg1	oxide					56:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	0	34	theme	antibacterial	130:142	arg1	properties					144:153	antibacterial properties	130:153	antibacterial properties	130:153	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	9	35	theme	chronic	1603:1609	arg1	treatment					1617:1625	chronic wound treatment	1603:1625	chronic wound treatment	1603:1625	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	3	36	dep	nanoparticles	558:570	arg1	ZnO-NPs					577:583	ZnO-NPs	577:583	zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	547:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	3	36	dep	nanoparticles	558:570	arg1	w/w					614:616	0, 0.001, 0.01, 0.1 and 1 % w/w	586:616	0, 0.001, 0.01, 0.1 and 1 % w/w	586:616	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	6	37	theme	lactate	1206:1212	arg1	LDH					1229:1231	LDH	1229:1231	LDH	1229:1231	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	37	theme	lactate	1206:1212	arg1	dehydrogenase					1214:1226	lactate dehydrogenase	1206:1226	lactate dehydrogenase (LDH)	1206:1232	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	1	38	theme	regenerative	203:214	arg1	applications					225:236	regenerative medicine applications	203:236	regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation	203:324	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	9	39	theme	developed	1525:1533	arg1	gels					1545:1548	the developed composite gels	1521:1548	the developed composite gels	1521:1548	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	6	40	theme	stem	1176:1179	arg1	ADSCs					1188:1192	ADSCs	1188:1192	ADSCs	1188:1192	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	40	theme	stem	1176:1179	arg1	cells					1181:1185	human adipose stem cells	1162:1185	human adipose stem cells (ADSCs)	1162:1193	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	2	41	theme	present	331:337	arg1	study					339:343	The present study	327:343	The present study	327:343	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	1	42	theme	medicine	216:223	arg1	applications					225:236	regenerative medicine applications	203:236	regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation	203:324	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	3	43	theme	good	735:738	arg1	activities					754:763	good antibacterial activities	735:763	good antibacterial activities	735:763	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	4	44	theme	Scanning	821:828	arg1	SEM					851:853	SEM	851:853	SEM	851:853	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	44	theme	Scanning	821:828	arg1	microscopy					839:848	Scanning electron microscopy	821:848	Scanning electron microscopy (SEM) analysis	821:863	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	0	45	theme	alginate	41:48	arg1	oxide					56:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
36758760	4	46	dep	transform	874:882	arg1	infrared					884:891	infrared	884:891	transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis	874:948	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	3	47	theme	antimicrobial	626:638	arg1	agent					640:644	the antimicrobial agent	622:644	the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	622:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	3	48	theme	%	612:612	arg1	ZnO-NPs					577:583	ZnO-NPs	577:583	zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	547:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	3	48	theme	%	612:612	arg1	w/w					614:616	0, 0.001, 0.01, 0.1 and 1 % w/w	586:616	0, 0.001, 0.01, 0.1 and 1 % w/w	586:616	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	1	49	theme	due	238:240	arg1	applications					225:236	regenerative medicine applications	203:236	regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation	203:324	Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation.					
36758760	4	50	dep	Fourier	866:872	arg1	transform					874:882	transform	874:882	transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis	874:948	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	3	51	dep	S.	714:715	arg1	aureus					717:722	S. aureus	714:722	S. aureus	714:722	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	5	52	theme	release	1066:1072	arg1	kinetics					1074:1081	controlled release kinetics	1055:1081	controlled release kinetics of ZnO-NPs	1055:1092	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	4	53	theme	microscopy	839:848	arg1	analysis					856:863	Scanning electron microscopy (SEM) analysis	821:863	Scanning electron microscopy (SEM) analysis	821:863	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	53	theme	microscopy	839:848	arg1	spectroscopy					807:818	UV visible spectroscopy	796:818	UV visible spectroscopy	796:818	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	2	54	theme	hydrogel	376:383	arg1	scaffold					395:402	a porous hydrogel composite scaffold	367:402	a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds	367:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	2	55	theme	wounds	475:480	arg1	repair					452:457	the repair	448:457	the repair of chronic skin wounds	448:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	4	56	theme	X-ray	917:921	arg1	XRD					936:938	XRD	936:938	XRD	936:938	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	56	theme	X-ray	917:921	arg1	diffraction					923:933	X-ray diffraction	917:933	X-ray diffraction (XRD)	917:939	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	5	57	theme	swelling	1014:1021	arg1	ratio					1023:1027	swelling ratio	1014:1027	swelling ratio	1014:1027	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	4	58	theme	electron	830:837	arg1	SEM					851:853	SEM	851:853	SEM	851:853	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	58	theme	electron	830:837	arg1	microscopy					839:848	Scanning electron microscopy	821:848	Scanning electron microscopy (SEM) analysis	821:863	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	3	59	theme	oxide	552:556	arg1	nanoparticles					558:570	zinc oxide nanoparticles	547:570	zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	547:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	2	60	theme	porous	369:374	arg1	scaffold					395:402	a porous hydrogel composite scaffold	367:402	a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds	367:480	The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds.					
36758760	8	61	theme	Fluorescence	1385:1396	arg1	PKH26					1398:1402	Fluorescence PKH26	1385:1402	Fluorescence PKH26	1385:1402	Fluorescence PKH26 stained images and SEM analysis of ADSCs seeded scaffolds revealed biocompatible nature.					
36758760	6	62	theme	SEM	1261:1263	arg1	analysis					1265:1272	SEM analysis	1261:1272	SEM analysis	1261:1272	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	7	63	theme	XRD	1306:1308	arg1	analysis					1310:1317	The SEM and XRD analysis	1294:1317	analysis	1310:1317	The SEM and XRD analysis confirmed the successful loading of ZnO-NPs into these scaffolds.					
36758760	4	64	theme	UV	796:797	arg1	Fourier					866:872	Fourier	866:872	Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis	866:948	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	64	theme	UV	796:797	arg1	analysis					856:863	Scanning electron microscopy (SEM) analysis	821:863	Scanning electron microscopy (SEM) analysis	821:863	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	64	theme	UV	796:797	arg1	spectroscopy					807:818	UV visible spectroscopy	796:818	UV visible spectroscopy	796:818	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	9	65	theme	tissue	1580:1585	arg1	engineering					1587:1597	tissue engineering	1580:1597	tissue engineering	1580:1597	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	6	66	theme	composite	1129:1137	arg1	cytocompatibility					1104:1120	In vitro cytocompatibility	1095:1120	In vitro cytocompatibility of the composite	1095:1137	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	6	67	theme	PKH26	1278:1282	arg1	staining					1284:1291	PKH26 staining	1278:1291	PKH26 staining	1278:1291	In vitro cytocompatibility of the composite was investigated using human adipose stem cells (ADSCs) by MTT and lactate dehydrogenase (LDH) assay, further assessed by SEM analysis and PKH26 staining.					
36758760	9	68	theme	composite	1535:1543	arg1	gels					1545:1548	the developed composite gels	1521:1548	the developed composite gels	1521:1548	The findings suggested that the developed composite gels have potential clinically for tissue engineering and chronic wound treatment.					
36758760	8	69	theme	seeded	1445:1450	arg1	scaffolds					1452:1460	ADSCs seeded scaffolds	1439:1460	ADSCs seeded scaffolds	1439:1460	Fluorescence PKH26 stained images and SEM analysis of ADSCs seeded scaffolds revealed biocompatible nature.					
36758760	5	70	theme	SEM	989:991	arg1	analysis					993:1000	SEM analysis	989:1000	SEM analysis	989:1000	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	3	71	theme	varying	521:527	arg1	concentrations					529:542	varying concentrations	521:542	varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	521:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	8	72	theme	SEM	1423:1425	arg1	analysis					1427:1434	SEM analysis	1423:1434	SEM analysis of ADSCs seeded scaffolds	1423:1460	Fluorescence PKH26 stained images and SEM analysis of ADSCs seeded scaffolds revealed biocompatible nature.					
36758760	5	73	theme	degradation	1030:1040	arg1	behavior					1042:1049	degradation behavior	1030:1049	degradation behavior	1030:1049	Fabricated gels were characterized by SEM analysis, FTIR, XRD, swelling ratio, degradation behavior and controlled release kinetics of ZnO-NPs.					
36758760	7	74	theme	SEM	1298:1300	arg1	analysis					1310:1317	The SEM and XRD analysis	1294:1317	analysis	1310:1317	The SEM and XRD analysis confirmed the successful loading of ZnO-NPs into these scaffolds.					
36758760	3	75	theme	Chitosan-based	483:496	arg1	hydrogel					498:505	Chitosan-based hydrogel	483:505	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	483:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	3	76	theme	nanoparticles	558:570	arg1	concentrations					529:542	varying concentrations	521:542	varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus)	521:723	Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.e. ZnO-NPs (0, 0.001, 0.01, 0.1 and 1 % w/w) as the antimicrobial agent tested against Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) exhibited good antibacterial activities.					
36758760	4	77	theme	visible	799:805	arg1	Fourier					866:872	Fourier	866:872	Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis	866:948	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	77	theme	visible	799:805	arg1	analysis					856:863	Scanning electron microscopy (SEM) analysis	821:863	Scanning electron microscopy (SEM) analysis	821:863	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	4	77	theme	visible	799:805	arg1	spectroscopy					807:818	UV visible spectroscopy	796:818	UV visible spectroscopy	796:818	ZnO-NPs were characterized by UV visible spectroscopy, Scanning electron microscopy (SEM) analysis, Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis.					
36758760	0	78	theme	gelation	7:14	arg1	oxide					56:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide	0:60	Freeze gelation (chitosan-elastin‑sodium alginate)/zinc oxide nanocomposite gel with enhanced adipose stem cell proliferation and antibacterial properties.					
37003583	11	0	theme	real	1505:1508	arg1	samples					1516:1522	real water samples	1505:1522	real water samples	1505:1522	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	7	1	theme	enhanced	843:850	arg1	reduction					862:870	the enhanced selective reduction	839:870	the enhanced selective reduction of toxins and hydrogen production	839:904	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	8	2	theme	catalytic	957:965	arg1	reduction					967:975	Effective catalytic reduction	947:975	Effective catalytic reduction	947:975	Effective catalytic reduction and hydrogen generation was successfully achieved with Co0@ZnPc-CH and ZnPc-CH.					
37003583	9	3	theme	fast	1167:1170	arg1	kinetics					1187:1194	the fast 4-NP reduction kinetics	1163:1194	the fast 4-NP reduction kinetics (K = 0.611 min-1)	1163:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	9	3	theme	fast	1167:1170	arg1	min-1					1207:1211	K = 0.611 min-1	1197:1211	K = 0.611 min-1	1197:1211	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	2	4	theme	overall	326:332	arg1	cost					343:346	the overall reaction cost	322:346	the overall reaction cost	322:346	A catalyst must be recovered and re-used effectively and economically to lower the overall reaction cost.					
37003583	11	5	theme	Co0	1381:1383	arg1	ZnPc-CH					1385:1391	Co0@ZnPc-CH	1381:1391	Co0@ZnPc-CH	1381:1391	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	6	6	theme	ZnPc-CH	770:776	arg1	surface					787:793	ZnPc-CH hydrogel surface	770:793	ZnPc-CH hydrogel surface	770:793	Metal nanoparticles (M0) based on Cu0, Ag0, Ni0, Co0 and Fe0 were decorated inside and on ZnPc-CH hydrogel surface.					
37003583	1	7	theme	organic	209:215	arg1	reactions					232:240	various organic transformation reactions	201:240	various organic transformation reactions	201:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	5	8	theme	metal	659:663	arg1	nanoparticles					665:677	the loaded metal nanoparticles	648:677	the loaded metal nanoparticles	648:677	The ZnPc-CH support facilitate the easy recovery of the loaded metal nanoparticles.					
37003583	7	9	theme	@	812:812	arg1	ZnPc-CH					813:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	7	10	theme	developed	800:808	arg1	ZnPc-CH					813:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	9	11	theme	@	1088:1088	arg1	ZnPc-CH					1089:1095	Co0@ZnPc-CH	1085:1095	Co0@ZnPc-CH	1085:1095	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	12	12	theme	H2	1575:1576	arg1	quantity					1563:1570	same quantity	1558:1570	same quantity of H2 throughout 4 continuous cycles of durability testing	1558:1629	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	9	13	from	reduction	1113:1121	arg1	8.0 min					1150:1156	8.0 min	1150:1156	8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1)	1150:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	1	14	theme	Metal	146:150	arg1	nanoparticles					152:164	Metal nanoparticles	146:164	Metal nanoparticles	146:164	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	6	15	theme	Metal	680:684	arg1	M0					701:702	M0	701:702	M0	701:702	Metal nanoparticles (M0) based on Cu0, Ag0, Ni0, Co0 and Fe0 were decorated inside and on ZnPc-CH hydrogel surface.					
37003583	6	15	theme	Metal	680:684	arg1	nanoparticles					686:698	Metal nanoparticles	680:698	Metal nanoparticles (M0) based on Cu0, Ag0, Ni0, Co0 and Fe0	680:739	Metal nanoparticles (M0) based on Cu0, Ag0, Ni0, Co0 and Fe0 were decorated inside and on ZnPc-CH hydrogel surface.					
37003583	3	16	theme	catalyst	367:374	arg1	recovery					353:360	The recovery	349:360	The recovery of a catalyst	349:374	The recovery of a catalyst remains a challenge due to their extreme small size.					
37003583	4	17	theme	catalytic	452:460	arg1	nanoparticles					468:480	catalytic metal nanoparticles	452:480	catalytic metal nanoparticles	452:480	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	11	18	theme	catalyst	1432:1439	arg1	recycling					1415:1423	recycling	1415:1423	recycling of the catalyst	1415:1439	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	0	19	theme	Bifunctional	73:84	arg1	catalysts					86:94	Bifunctional catalysts	73:94	metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production	52:143	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	1	20	theme	catalytic	179:187	arg1	activity					189:196	high catalytic activity	174:196	high catalytic activity in various organic transformation reactions	174:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	11	21	theme	4-NP	1485:1488	arg1	treatment					1490:1498	4-NP treatment	1485:1498	4-NP treatment	1485:1498	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	1	22	from	activity	189:196	arg1	reactions					232:240	various organic transformation reactions	201:240	various organic transformation reactions	201:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	8	23	theme	hydrogen	981:988	arg1	generation					990:999	hydrogen generation	981:999	hydrogen generation	981:999	Effective catalytic reduction and hydrogen generation was successfully achieved with Co0@ZnPc-CH and ZnPc-CH.					
37003583	8	24	theme	@	1035:1035	arg1	ZnPc-CH					1036:1042	Co0@ZnPc-CH	1032:1042	Co0@ZnPc-CH	1032:1042	Effective catalytic reduction and hydrogen generation was successfully achieved with Co0@ZnPc-CH and ZnPc-CH.					
37003583	5	25	theme	easy	631:634	arg1	recovery					636:643	the easy recovery	627:643	the easy recovery of the loaded metal nanoparticles	627:677	The ZnPc-CH support facilitate the easy recovery of the loaded metal nanoparticles.					
37003583	12	26	theme	testing	1623:1629	arg1	cycles					1602:1607	4 continuous cycles	1589:1607	4 continuous cycles of durability testing	1589:1629	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	10	27	theme	fast	1261:1264	arg1	generation					1269:1278	fast H2 generation	1261:1278	fast H2 generation	1261:1278	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	0	28	theme	hydrogen	125:132	arg1	production					134:143	hydrogen production	125:143	hydrogen production	125:143	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	3	29	theme	small	417:421	arg1	size					423:426	their extreme small size	403:426	their extreme small size	403:426	The recovery of a catalyst remains a challenge due to their extreme small size.					
37003583	9	30	theme	Co0	1085:1087	arg1	ZnPc-CH					1089:1095	Co0@ZnPc-CH	1085:1095	Co0@ZnPc-CH	1085:1095	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	0	31	theme	Chitosan	0:7	arg1	hydrogel					9:16	Chitosan hydrogel	0:16	Chitosan hydrogel anchored phthalocyanine	0:40	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	5	32	theme	ZnPc-CH	600:606	arg1	support					608:614	The ZnPc-CH support	596:614	The ZnPc-CH support	596:614	The ZnPc-CH support facilitate the easy recovery of the loaded metal nanoparticles.					
37003583	12	33	theme	continuous	1591:1600	arg1	cycles					1602:1607	4 continuous cycles	1589:1607	4 continuous cycles of durability testing	1589:1629	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	9	34	theme	4-NP	1172:1175	arg1	kinetics					1187:1194	the fast 4-NP reduction kinetics	1163:1194	the fast 4-NP reduction kinetics (K = 0.611 min-1)	1163:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	9	34	theme	4-NP	1172:1175	arg1	min-1					1207:1211	K = 0.611 min-1	1197:1211	K = 0.611 min-1	1197:1211	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	10	35	theme	high	1285:1288	arg1	rate					1304:1307	high H2 generation rate	1285:1307	high H2 generation rate (HGR = 4100 mLg-1min-1)	1285:1331	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	10	35	theme	high	1285:1288	arg1	mLg-1min-1					1321:1330	HGR = 4100 mLg-1min-1	1310:1330	HGR = 4100 mLg-1min-1	1310:1330	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	0	36	theme	anchored	18:25	arg1	phthalocyanine					27:40	Chitosan hydrogel anchored phthalocyanine	0:40	Chitosan hydrogel anchored phthalocyanine	0:40	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	4	37	theme	catalyst	578:585	arg1	support					587:593	catalyst support	578:593	catalyst support	578:593	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	9	38	theme	complete	1104:1111	arg1	reduction					1113:1121	complete reduction	1104:1121	complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1)	1104:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	0	39	dep	nanoparticles	58:70	arg1	catalysts					86:94	Bifunctional catalysts	73:94	metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production	52:143	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	9	40	theme	reduction	1177:1185	arg1	kinetics					1187:1194	the fast 4-NP reduction kinetics	1163:1194	the fast 4-NP reduction kinetics (K = 0.611 min-1)	1163:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	9	40	theme	reduction	1177:1185	arg1	min-1					1207:1211	K = 0.611 min-1	1197:1211	K = 0.611 min-1	1197:1211	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	10	41	theme	generation	1293:1302	arg1	rate					1304:1307	high H2 generation rate	1285:1307	high H2 generation rate (HGR = 4100 mLg-1min-1)	1285:1331	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	10	41	theme	generation	1293:1302	arg1	mLg-1min-1					1321:1330	HGR = 4100 mLg-1min-1	1310:1330	HGR = 4100 mLg-1min-1	1310:1330	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	7	42	theme	production	895:904	arg1	reduction					862:870	the enhanced selective reduction	839:870	the enhanced selective reduction of toxins and hydrogen production	839:904	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	12	43	theme	catalyst	1768:1775	arg1	effectiveness					1747:1759	the effectiveness	1743:1759	the effectiveness of the catalyst to be applied to H2 production on large scale	1743:1821	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	11	44	theme	Metal	1361:1365	arg1	leaching					1367:1374	Metal leaching	1361:1374	Metal leaching from Co0@ZnPc-CH	1361:1391	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	8	45	theme	Effective	947:955	arg1	reduction					967:975	Effective catalytic reduction	947:975	Effective catalytic reduction	947:975	Effective catalytic reduction and hydrogen generation was successfully achieved with Co0@ZnPc-CH and ZnPc-CH.					
37003583	5	46	theme	nanoparticles	665:677	arg1	recovery					636:643	the easy recovery	627:643	the easy recovery of the loaded metal nanoparticles	627:677	The ZnPc-CH support facilitate the easy recovery of the loaded metal nanoparticles.					
37003583	7	47	used	utilized	826:833	arg2	ZnPc-CH					813:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	11	48	theme	@	1384:1384	arg1	ZnPc-CH					1385:1391	Co0@ZnPc-CH	1381:1391	Co0@ZnPc-CH	1381:1391	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	11	49	theme	water	1510:1514	arg1	samples					1516:1522	real water samples	1505:1522	real water samples	1505:1522	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	2	50	theme	reaction	334:341	arg1	cost					343:346	the overall reaction cost	322:346	the overall reaction cost	322:346	A catalyst must be recovered and re-used effectively and economically to lower the overall reaction cost.					
37003583	7	51	theme	selective	852:860	arg1	reduction					862:870	the enhanced selective reduction	839:870	the enhanced selective reduction of toxins and hydrogen production	839:904	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	4	52	theme	research	437:444	arg1	work					446:449	this research work	432:449	this research work	432:449	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	6	53	theme	hydrogel	778:785	arg1	surface					787:793	ZnPc-CH hydrogel surface	770:793	ZnPc-CH hydrogel surface	770:793	Metal nanoparticles (M0) based on Cu0, Ag0, Ni0, Co0 and Fe0 were decorated inside and on ZnPc-CH hydrogel surface.					
37003583	1	54	theme	various	201:207	arg1	reactions					232:240	various organic transformation reactions	201:240	various organic transformation reactions	201:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	12	55	theme	continuous	1710:1719	arg1	reactions					1721:1729	continuous reactions	1710:1729	continuous reactions	1710:1729	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	5	56	theme	loaded	652:657	arg1	nanoparticles					665:677	the loaded metal nanoparticles	648:677	the loaded metal nanoparticles	648:677	The ZnPc-CH support facilitate the easy recovery of the loaded metal nanoparticles.					
37003583	1	57	theme	transformation	217:230	arg1	reactions					232:240	various organic transformation reactions	201:240	various organic transformation reactions	201:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	7	58	theme	M0	810:811	arg1	ZnPc-CH					813:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH	796:819	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	11	59	from	ZnPc-CH	1385:1391	arg1	leaching					1367:1374	Metal leaching	1361:1374	Metal leaching from Co0@ZnPc-CH	1361:1391	Metal leaching from Co0@ZnPc-CH was negligible during recycling of the catalyst, suggesting that it could be implemented to 4-NP treatment from real water samples.					
37003583	12	60	theme	same	1558:1561	arg1	quantity					1563:1570	same quantity	1558:1570	same quantity of H2 throughout 4 continuous cycles of durability testing	1558:1629	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	2	61	dep	cost	343:346	arg1	lower					316:320	lower	316:320	lower	316:320	A catalyst must be recovered and re-used effectively and economically to lower the overall reaction cost.					
37003583	4	62	theme	metal	462:466	arg1	nanoparticles					468:480	catalytic metal nanoparticles	452:480	catalytic metal nanoparticles	452:480	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	1	63	theme	high	174:177	arg1	activity					189:196	high catalytic activity	174:196	high catalytic activity in various organic transformation reactions	174:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	12	64	theme	high	1688:1691	arg1	stability					1693:1701	high stability	1688:1701	high stability	1688:1701	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	4	65	theme	chitosan	531:538	arg1	CH					550:551	CH	550:551	CH	550:551	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	4	65	theme	chitosan	531:538	arg1	hydrogel					540:547	chitosan hydrogel	531:547	chitosan hydrogel (CH)	531:552	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	0	66	theme	pollutants	100:109	arg1	reduction					111:119	pollutants reduction	100:119	pollutants reduction	100:119	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	8	67	theme	Co0	1032:1034	arg1	ZnPc-CH					1036:1042	Co0@ZnPc-CH	1032:1042	Co0@ZnPc-CH	1032:1042	Effective catalytic reduction and hydrogen generation was successfully achieved with Co0@ZnPc-CH and ZnPc-CH.					
37003583	10	68	theme	developed	1225:1233	arg1	catalysts					1235:1243	the developed catalysts	1221:1243	the developed catalysts	1221:1243	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	9	69	theme	optimized	1063:1071	arg1	conditions					1073:1082	optimized conditions	1063:1082	optimized conditions	1063:1082	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	10	70	theme	H2	1266:1267	arg1	generation					1269:1278	fast H2 generation	1261:1278	fast H2 generation	1261:1278	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	7	71	theme	NaBH4	940:944	arg1	hydrolysis					926:935	hydrolysis	926:935	hydrolysis	926:935	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	7	71	theme	NaBH4	940:944	arg1	methanolysis					909:920	methanolysis	909:920	methanolysis	909:920	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	12	72	theme	durability	1612:1621	arg1	testing					1623:1629	durability testing	1612:1629	durability testing	1612:1629	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	0	73	theme	hydrogel	9:16	arg1	phthalocyanine					27:40	Chitosan hydrogel anchored phthalocyanine	0:40	Chitosan hydrogel anchored phthalocyanine	0:40	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	10	74	theme	H2	1290:1291	arg1	rate					1304:1307	high H2 generation rate	1285:1307	high H2 generation rate (HGR = 4100 mLg-1min-1)	1285:1331	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	10	74	theme	H2	1290:1291	arg1	mLg-1min-1					1321:1330	HGR = 4100 mLg-1min-1	1310:1330	HGR = 4100 mLg-1min-1	1310:1330	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	3	75	theme	extreme	409:415	arg1	size					423:426	their extreme small size	403:426	their extreme small size	403:426	The recovery of a catalyst remains a challenge due to their extreme small size.					
37003583	0	76	theme	metal	52:56	arg1	nanoparticles					58:70	metal nanoparticles	52:70	metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production	52:143	Chitosan hydrogel anchored phthalocyanine supported metal nanoparticles: Bifunctional catalysts for pollutants reduction and hydrogen production.					
37003583	4	77	dep	Zn-phthalocyanine	502:518	arg1	composite					554:562	composite	554:562	composite	554:562	In this research work, catalytic metal nanoparticles were synthesized on Zn-phthalocyanine (ZnPc) and chitosan hydrogel (CH) composite which acts as catalyst support.					
37003583	12	78	theme	large	1811:1815	arg1	scale					1817:1821	large scale	1811:1821	large scale	1811:1821	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	9	79	theme	4-nitrophenol	1126:1138	arg1	reduction					1113:1121	complete reduction	1104:1121	complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1)	1104:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	7	80	theme	hydrogen	886:893	arg1	production					895:904	hydrogen production	886:904	hydrogen production	886:904	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	12	81	theme	H2	1794:1795	arg1	production					1797:1806	H2 production	1794:1806	H2 production	1794:1806	Similarly, ZnPc-CH could produce same quantity of H2 throughout 4 continuous cycles of durability testing without any deactivation and leaching and ZnPc-CH showed high stability within continuous reactions, indicating the effectiveness of the catalyst to be applied to H2 production on large scale.					
37003583	10	82	theme	optimized	1339:1347	arg1	conditions					1349:1358	optimized conditions	1339:1358	optimized conditions	1339:1358	Among the developed catalysts, ZnPc-CH showed fast H2 generation with high H2 generation rate (HGR = 4100 mLg-1min-1) under optimized conditions.					
37003583	7	83	theme	toxins	875:880	arg1	reduction					862:870	the enhanced selective reduction	839:870	the enhanced selective reduction of toxins and hydrogen production	839:904	The developed M0@ZnPc-CH were utilized for the enhanced selective reduction of toxins and hydrogen production by methanolysis and hydrolysis of NaBH4.					
37003583	9	84	with	8.0 min	1150:1156	arg1	kinetics					1187:1194	the fast 4-NP reduction kinetics	1163:1194	the fast 4-NP reduction kinetics (K = 0.611 min-1)	1163:1212	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	9	84	with	8.0 min	1150:1156	arg1	min-1					1207:1211	K = 0.611 min-1	1197:1211	K = 0.611 min-1	1197:1211	Under optimized conditions, Co0@ZnPc-CH showed complete reduction of 4-nitrophenol (4-NP) in 8.0 min with the fast 4-NP reduction kinetics (K = 0.611 min-1).					
37003583	1	85	contain	possess	166:172	arg1	nanoparticles					152:164	Metal nanoparticles	146:164	Metal nanoparticles	146:164	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
37003583	1	85	contain	possess	166:172	arg2	activity					189:196	high catalytic activity	174:196	high catalytic activity in various organic transformation reactions	174:240	Metal nanoparticles possess high catalytic activity in various organic transformation reactions.					
36235783	0	0	theme	Milk	78:81	arg1	Composition					99:109	Breast Milk Oligosaccharide Composition	71:109	Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China	71:141	Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China.					
36235783	7	1	theme	milk	1239:1242	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	1	theme	milk	1239:1242	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	3	2	dep	OBJECTIVES	381:390	arg1	investigated					395:406	investigated	395:406	investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population	395:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	3	3	from	concentrations	465:478	arg1	population					517:526	a general pregnant and postpartum population	483:526	a general pregnant and postpartum population	483:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	1	4	theme	Human	155:159	arg1	HMOs					184:187	HMOs	184:187	HMOs	184:187	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	4	theme	Human	155:159	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	4	theme	Human	155:159	arg1	oligosaccharides					166:181	BACKGROUND Human milk oligosaccharides	144:181	BACKGROUND Human milk oligosaccharides (HMOs)	144:188	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	4	theme	Human	155:159	arg1	group					196:200	a group	194:200	a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants	194:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	5	theme	pivotal	240:246	arg1	benefits					248:255	pivotal benefits	240:255	pivotal benefits	240:255	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	0	6	theme	Breast	71:76	arg1	Composition					99:109	Breast Milk Oligosaccharide Composition	71:109	Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China	71:141	Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China.					
36235783	5	7	theme	different	690:698	arg1	HMOs					700:703	Six different HMOs	686:703	Six different HMOs	686:703	Six different HMOs were detected in mothers' milk.					
36235783	1	8	theme	milk	161:164	arg1	HMOs					184:187	HMOs	184:187	HMOs	184:187	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	8	theme	milk	161:164	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	8	theme	milk	161:164	arg1	oligosaccharides					166:181	BACKGROUND Human milk oligosaccharides	144:181	BACKGROUND Human milk oligosaccharides (HMOs)	144:188	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	8	theme	milk	161:164	arg1	group					196:200	a group	194:200	a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants	194:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	4	9	theme	frequency	599:607	arg1	questionnaires					609:622	the corresponding food frequency questionnaires	576:622	the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers	576:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	2	10	theme	maternal	288:295	arg1	diet					297:300	maternal diet	288:300	maternal diet	288:300	Whether maternal diet is associated with breastmilk HMO composition has not been well-characterized.					
36235783	0	11	theme	Oligosaccharide	83:97	arg1	Composition					99:109	Breast Milk Oligosaccharide Composition	71:109	Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China	71:141	Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China.					
36235783	7	12	theme	metal	1159:1163	arg1	elements					1165:1172	metal elements	1159:1172	metal elements	1159:1172	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	3	13	theme	postpartum	506:515	arg1	population					517:526	a general pregnant and postpartum population	483:526	a general pregnant and postpartum population	483:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	7	14	theme	lacto-N-tetraose	1330:1345	arg1	levels					1308:1313	lacto-N-tetraose levels	1291:1313	lacto-N-tetraose levels	1291:1313	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	14	theme	lacto-N-tetraose	1330:1345	arg1	sum					1323:1325	the sum	1319:1325	the sum of lacto-N-tetraose and lacto-N-neotetraose	1319:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	15	theme	vitamin	875:881	arg1	nutrients					853:861	plant nutrients	847:861	plant nutrients	847:861	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	15	theme	vitamin	875:881	arg1	C					883:883	vitamin C	875:883	vitamin C	875:883	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	3	16	theme	HMO	461:463	arg1	concentrations					465:478	HMO concentrations	461:478	HMO concentrations	461:478	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	1	17	theme	breastfed	261:269	arg1	infants					271:277	breastfed infants	261:277	breastfed infants	261:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	7	18	theme	vitamin	959:965	arg1	B2					967:968	vitamin B2	959:968	vitamin B2	959:968	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	4	19	theme	postpartum	637:646	arg1	days					648:651	0-400 postpartum days	631:651	0-400 postpartum days from 277 mothers	631:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	7	20	theme	lacto-N-tetraose	1291:1306	arg1	levels					1308:1313	lacto-N-tetraose levels	1291:1313	lacto-N-tetraose levels	1291:1313	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	6	21	theme	mixed-effects	809:821	arg1	model					823:827	a linear mixed-effects model	800:827	a linear mixed-effects model	800:827	The correlation between nutrients and HMOs were analyzed using a linear mixed-effects model.					
36235783	7	22	theme	vitamin	864:870	arg1	nutrients					853:861	plant nutrients	847:861	plant nutrients	847:861	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	22	theme	vitamin	864:870	arg1	A					872:872	vitamin A	864:872	vitamin A	864:872	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	23	theme	lacto-N-neotetraose	1351:1369	arg1	levels					1308:1313	lacto-N-tetraose levels	1291:1313	lacto-N-tetraose levels	1291:1313	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	23	theme	lacto-N-neotetraose	1351:1369	arg1	sum					1323:1325	the sum	1319:1325	the sum of lacto-N-tetraose and lacto-N-neotetraose	1319:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	24	theme	plant	847:851	arg1	nutrients					853:861	plant nutrients	847:861	plant nutrients	847:861	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	24	theme	plant	847:851	arg1	A					872:872	vitamin A	864:872	vitamin A	864:872	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	24	theme	plant	847:851	arg1	C					883:883	vitamin C	875:883	vitamin C	875:883	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	24	theme	plant	847:851	arg1	vegetables					889:898	vegetables	889:898	vegetables as positive predictors of 3-fucosyllactose	889:941	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	6	25	theme	linear	802:807	arg1	model					823:827	a linear mixed-effects model	800:827	a linear mixed-effects model	800:827	The correlation between nutrients and HMOs were analyzed using a linear mixed-effects model.					
36235783	5	26	located	detected	710:717	arg2	HMOs					700:703	Six different HMOs	686:703	Six different HMOs	686:703	Six different HMOs were detected in mothers' milk.					
36235783	5	26	located	detected	710:717	arg1	milk					731:734	mothers' milk	722:734	mothers' milk	722:734	Six different HMOs were detected in mothers' milk.					
36235783	3	27	theme	general	485:491	arg1	population					517:526	a general pregnant and postpartum population	483:526	a general pregnant and postpartum population	483:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	4	28	theme	food	594:597	arg1	questionnaires					609:622	the corresponding food frequency questionnaires	576:622	the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers	576:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	7	29	theme	positive	1113:1120	arg1	predictors					1122:1131	positive predictors	1113:1131	positive predictors for 3'-sialyllactose	1113:1152	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	30	theme	positive	975:982	arg1	predictors					984:993	positive predictors	975:993	positive predictors for 2'-fucosyllactose level	975:1021	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	3	31	theme	pregnant	493:500	arg1	population					517:526	a general pregnant and postpartum population	483:526	a general pregnant and postpartum population	483:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	3	32	theme	dietary	433:439	arg1	intake					450:455	dietary nutrient intake	433:455	dietary nutrient intake	433:455	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	4	33	theme	corresponding	580:592	arg1	questionnaires					609:622	the corresponding food frequency questionnaires	576:622	the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers	576:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	7	34	theme	metal	1093:1097	arg1	elements					1099:1106	metal elements	1093:1106	metal elements	1093:1106	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	8	35	theme	HMO	1496:1498	arg1	concentrations					1500:1513	HMO concentrations	1496:1513	HMO concentrations	1496:1513	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	36	dep	CONCLUSIONS	1372:1382	arg1	show					1396:1399	show	1396:1399	show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations	1396:1513	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	4	37	from	mothers	662:668	arg1	days					648:651	0-400 postpartum days	631:651	0-400 postpartum days from 277 mothers	631:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	0	38	theme	Metal	25:29	arg1	Elements					31:38	Metal Elements	25:38	Metal Elements	25:38	Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China.					
36235783	4	39	theme	breast	552:557	arg1	samples					564:570	383 breast milk samples	548:570	383 breast milk samples	548:570	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	3	40	theme	nutrient	441:448	arg1	intake					450:455	dietary nutrient intake	433:455	dietary nutrient intake	433:455	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	8	41	theme	metal	1431:1435	arg1	vegetables					1406:1415	vegetables	1406:1415	vegetables	1406:1415	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	41	theme	metal	1431:1435	arg1	vitamins					1418:1425	vitamins	1418:1425	vitamins	1418:1425	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	41	theme	metal	1431:1435	arg1	elements					1437:1444	metal elements	1431:1444	metal elements	1431:1444	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	41	theme	metal	1431:1435	arg1	components					1458:1467	dietary components	1450:1467	dietary components positively associated with HMO concentrations	1450:1513	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	7	42	theme	2'-fucosyllactose	1038:1054	arg1	predictors					984:993	positive predictors	975:993	positive predictors for 2'-fucosyllactose level	975:1021	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	42	theme	2'-fucosyllactose	1038:1054	arg1	sum					1031:1033	the sum	1027:1033	the sum of 2'-fucosyllactose and 3-fucosyllactose	1027:1075	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	4	43	dep	METHODS	529:535	arg1	collected					675:683	collected	675:683	were collected	670:683	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	4	44	theme	383	548:550	arg1	samples					564:570	383 breast milk samples	548:570	383 breast milk samples	548:570	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	8	45	theme	dietary	1450:1456	arg1	vitamins					1418:1425	vitamins	1418:1425	vitamins	1418:1425	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	45	theme	dietary	1450:1456	arg1	vegetables					1406:1415	vegetables	1406:1415	vegetables	1406:1415	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	45	theme	dietary	1450:1456	arg1	components					1458:1467	dietary components	1450:1467	dietary components positively associated with HMO concentrations	1450:1513	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	8	45	theme	dietary	1450:1456	arg1	elements					1437:1444	metal elements	1431:1444	metal elements	1431:1444	CONCLUSIONS The results show that vegetables, vitamins and metal elements are dietary components positively associated with HMO concentrations.					
36235783	7	46	theme	levels	1308:1313	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	46	theme	levels	1308:1313	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	4	47	theme	samples	564:570	arg1	total					539:543	A total	537:543	A total of 383 breast milk samples	537:570	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	4	47	theme	samples	564:570	arg1	questionnaires					609:622	the corresponding food frequency questionnaires	576:622	the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers	576:668	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	7	48	theme	HMOs	1229:1232	arg1	sum					1210:1212	the sum	1206:1212	the sum of all the six HMOs	1206:1232	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	0	49	from	Mothers	117:123	arg1	China					137:141	China	137:141	China	137:141	Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China.					
36235783	4	50	theme	milk	559:562	arg1	samples					564:570	383 breast milk samples	548:570	383 breast milk samples	548:570	METHODS A total of 383 breast milk samples and the corresponding food frequency questionnaires during 0-400 postpartum days from 277 mothers were collected.					
36235783	7	51	theme	3-fucosyllactose	1060:1075	arg1	predictors					984:993	positive predictors	975:993	positive predictors for 2'-fucosyllactose level	975:1021	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	51	theme	3-fucosyllactose	1060:1075	arg1	sum					1031:1033	the sum	1027:1033	the sum of 2'-fucosyllactose and 3-fucosyllactose	1027:1075	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	2	52	theme	HMO	332:334	arg1	composition					336:346	breastmilk HMO composition	321:346	breastmilk HMO composition	321:346	Whether maternal diet is associated with breastmilk HMO composition has not been well-characterized.					
36235783	7	53	theme	vitamin	944:950	arg1	B1					952:953	vitamin B1	944:953	vitamin B1	944:953	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	1	54	theme	breast	205:210	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	3	55	from	intake	450:455	arg1	population					517:526	a general pregnant and postpartum population	483:526	a general pregnant and postpartum population	483:526	OBJECTIVES We investigated the associations between dietary nutrient intake and HMO concentrations in a general pregnant and postpartum population.					
36235783	2	56	theme	breastmilk	321:330	arg1	composition					336:346	breastmilk HMO composition	321:346	breastmilk HMO composition	321:346	Whether maternal diet is associated with breastmilk HMO composition has not been well-characterized.					
36235783	1	57	theme	milk	212:215	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	7	58	theme	lactose	1248:1254	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	58	theme	lactose	1248:1254	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	59	theme	sum	1323:1325	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	59	theme	sum	1323:1325	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	60	theme	positive	1269:1276	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	60	theme	positive	1269:1276	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	61	theme	3-fucosyllactose	926:941	arg1	predictors					912:921	positive predictors	903:921	positive predictors of 3-fucosyllactose	903:941	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	1	62	theme	carbohydrates	217:229	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	62	theme	carbohydrates	217:229	arg1	oligosaccharides					166:181	BACKGROUND Human milk oligosaccharides	144:181	BACKGROUND Human milk oligosaccharides (HMOs)	144:188	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	62	theme	carbohydrates	217:229	arg1	group					196:200	a group	194:200	a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants	194:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	7	63	dep	RESULTS	830:836	arg1	predictors					1122:1131	positive predictors	1113:1131	positive predictors for 3'-sialyllactose	1113:1152	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	63	dep	RESULTS	830:836	arg1	predictor					1278:1286	a positive predictor	1267:1286	a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose	1267:1369	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	63	dep	RESULTS	830:836	arg1	predictors					984:993	positive predictors	975:993	positive predictors for 2'-fucosyllactose level	975:1021	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	63	dep	RESULTS	830:836	arg1	found					841:845	found	841:845	found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose	841:941	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	63	dep	RESULTS	830:836	arg1	associated					1190:1199	associated	1190:1199	were positively associated with the sum of all the six HMOs	1174:1232	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	63	dep	RESULTS	830:836	arg1	intake					1256:1261	the milk and lactose intake	1235:1261	intake	1256:1261	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	7	64	theme	2'-fucosyllactose	999:1015	arg1	level					1017:1021	2'-fucosyllactose level	999:1021	2'-fucosyllactose level	999:1021	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
36235783	1	65	theme	BACKGROUND	144:153	arg1	HMOs					184:187	HMOs	184:187	HMOs	184:187	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	65	theme	BACKGROUND	144:153	arg1	carbohydrates					217:229	breast milk carbohydrates	205:229	breast milk carbohydrates exerting pivotal benefits for breastfed infants	205:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	65	theme	BACKGROUND	144:153	arg1	oligosaccharides					166:181	BACKGROUND Human milk oligosaccharides	144:181	BACKGROUND Human milk oligosaccharides (HMOs)	144:188	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	1	65	theme	BACKGROUND	144:153	arg1	group					196:200	a group	194:200	a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants	194:277	BACKGROUND Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants.					
36235783	7	66	theme	positive	903:910	arg1	predictors					912:921	positive predictors	903:921	positive predictors of 3-fucosyllactose	903:941	RESULTS We found plant nutrients, vitamin A, vitamin C and vegetables as positive predictors of 3-fucosyllactose; vitamin B1 and vitamin B2 were positive predictors for 2'-fucosyllactose level and the sum of 2'-fucosyllactose and 3-fucosyllactose; tocopherol and metal elements were positive predictors for 3'-sialyllactose; and metal elements were positively associated with the sum of all the six HMOs; the milk and lactose intake was a positive predictor of lacto-N-tetraose levels and the sum of lacto-N-tetraose and lacto-N-neotetraose.					
35850070	6	0	theme	isotherm	1098:1105	arg1	models					1107:1112	the Langmuir and Sips isotherm models	1076:1112	models	1107:1112	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	6	1	theme	maximum	1119:1125	arg1	capacities					1138:1147	the maximum adsorption capacities	1115:1147	the maximum adsorption capacities	1115:1147	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	6	1	theme	maximum	1119:1125	arg1	high					1159:1162	high	1159:1162	high	1159:1162	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	5	2	theme	time	924:927	arg1	evolution					929:937	The time evolution	920:937	The time evolution	920:937	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	3	3	theme	contaminant	709:719	arg1	processes					686:694	The sorption processes	673:694	The sorption processes of the model contaminant, crystal violet (CV),	673:741	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	5	4	theme	two-model	960:968	arg1	model					991:995	a two-model, pseudo second-order model	958:995	a two-model, pseudo second-order model (CG and CGC)	958:1008	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	6	5	theme	Sips	1093:1096	arg1	models					1107:1112	the Langmuir and Sips isotherm models	1076:1112	models	1107:1112	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	2	6	theme	functional	542:551	arg1	groups					553:558	functional groups	542:558	functional groups	542:558	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	1	7	dep	cellulose	353:361	arg1	CTCD					371:374	CTCD	371:374	CTCD	371:374	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	7	dep	cellulose	353:361	arg1	CT					364:365	CT	364:365	CT	364:365	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	9	8	theme	samples	1539:1545	arg1	treatment					1510:1518	the treatment	1506:1518	the treatment of real wastewater samples	1506:1545	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	0	9	from	Cellulose	0:8	arg1	race					87:90	the race	83:90	the race	83:90	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	9	10	theme	dyes	1481:1484	arg1	removal					1461:1467	almost complete removal	1445:1467	almost complete removal of cationic dyes	1445:1484	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	5	11	theme	first-order	1021:1031	arg1	model					1033:1037	pseudo first-order model	1014:1037	pseudo first-order model	1014:1037	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	1	12	theme	cellulose	307:315	arg1	types					298:302	two types	294:302	two types of cellulose (CGC and CC)	294:328	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	12	theme	cellulose	307:315	arg1	CC					326:327	CC	326:327	CC	326:327	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	12	theme	cellulose	307:315	arg1	CGC					318:320	CGC	318:320	CGC	318:320	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	12	theme	cellulose	307:315	arg1	grounds					280:286	coffee grounds	273:286	coffee grounds (CG)	273:291	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	2	13	theme	FTIR	654:657	arg1	spectroscopy					659:670	FTIR spectroscopy	654:670	FTIR spectroscopy	654:670	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	3	14	theme	model	703:707	arg1	contaminant					709:719	the model contaminant	699:719	the model contaminant	699:719	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	3	14	theme	model	703:707	arg1	violet					730:735	crystal violet	722:735	crystal violet (CV)	722:740	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	0	15	from	grounds	38:44	arg1	race					87:90	the race	83:90	the race	83:90	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	0	16	theme	sustainable	180:190	arg1	development					192:202	sustainable development	180:202	sustainable development	180:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	3	17	theme	equilibrium	772:782	arg1	models					784:789	kinetics and equilibrium models	759:789	kinetics and equilibrium models	759:789	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	6	18	from	case	1172:1175	arg1	capacities					1138:1147	the maximum adsorption capacities	1115:1147	the maximum adsorption capacities	1115:1147	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	6	18	from	case	1172:1175	arg1	high					1159:1162	high	1159:1162	high	1159:1162	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	2	19	theme	obtained	567:574	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	7	20	theme	adsorption	1231:1240	arg1	capacity					1242:1249	the adsorption capacity	1227:1249	the adsorption capacity of the near-natural materials	1227:1279	Moreover, the adsorption capacity of the near-natural materials remained even higher after five regeneration cycles.					
35850070	1	21	dep	β-cyclodextrin	395:408	arg1	CD-1					411:414	CD-1	411:414	CD-1	411:414	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	21	dep	β-cyclodextrin	395:408	arg1	CD-2					420:423	CD-2	420:423	CD-2	420:423	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	7	22	theme	near-natural	1258:1269	arg1	materials					1271:1279	the near-natural materials	1254:1279	the near-natural materials	1254:1279	Moreover, the adsorption capacity of the near-natural materials remained even higher after five regeneration cycles.					
35850070	5	23	dep	two-model	960:968	arg1	pseudo					971:976	pseudo	971:976	pseudo	971:976	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	3	24	theme	kinetics	759:766	arg1	models					784:789	kinetics and equilibrium models	759:789	kinetics and equilibrium models	759:789	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	2	25	dep	composition	501:511	arg1	The					497:499	The	497:499	The	497:499	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	1	26	dep	types	298:302	arg1	types					298:302	two types	294:302	two types of cellulose (CGC and CC)	294:328	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	26	dep	types	298:302	arg1	CC					326:327	CC	326:327	CC	326:327	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	26	dep	types	298:302	arg1	CGC					318:320	CGC	318:320	CGC	318:320	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	0	27	theme	development	192:202	arg1	principles					166:175	the principles	162:175	the principles of sustainable development	162:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	9	28	theme	cationic	1472:1479	arg1	dyes					1481:1484	cationic dyes	1472:1484	cationic dyes	1472:1484	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	4	29	theme	slowest	875:881	arg1	adsorption					883:892	the slowest adsorption	871:892	the slowest adsorption	871:892	The results showed, that using CTCD, the dye was adsorbed rapidly in 1 min and the slowest adsorption occurred in 20 min by CG.					
35850070	0	30	theme	highest	100:106	arg1	capacity					117:124	the highest sorption capacity	96:124	the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development	96:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	1	31	theme	cross-linked	382:393	arg1	β-cyclodextrin					395:408	cross-linked β-cyclodextrin	382:408	cross-linked β-cyclodextrin (CD-1 and CD-2)	382:424	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	31	theme	cross-linked	382:393	arg1	adsorbents					441:450	adsorbents	441:450	adsorbents	441:450	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	32	theme	different	226:234	arg1	materials					236:244	seven different materials	220:244	seven different materials	220:244	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	9	33	theme	real	1523:1526	arg1	samples					1539:1545	real wastewater samples	1523:1545	real wastewater samples	1523:1545	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	0	34	from	β-cyclodextrin	65:78	arg1	race					87:90	the race	83:90	the race	83:90	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	1	35	from	wastewater	485:494	arg1	dyes					471:474	dyes	471:474	dyes from the wastewater	471:494	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	35	from	wastewater	485:494	arg1	removal					460:466	the removal	456:466	the removal of dyes from the wastewater	456:494	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	36	theme	dyes	471:474	arg1	removal					460:466	the removal	456:466	the removal of dyes from the wastewater	456:494	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	9	37	located	observed	1490:1497	arg2	removal					1461:1467	almost complete removal	1445:1467	almost complete removal of cationic dyes	1445:1484	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	9	37	located	observed	1490:1497	arg1	addition					1435:1442	addition	1435:1442	addition	1435:1442	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	0	38	theme	coffee	31:36	arg1	grounds					38:44	coffee grounds	31:44	coffee grounds	31:44	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	1	39	theme	coffee	273:278	arg1	types					298:302	two types	294:302	two types of cellulose (CGC and CC)	294:328	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	39	theme	coffee	273:278	arg1	CG					289:290	CG	289:290	CG	289:290	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	39	theme	coffee	273:278	arg1	types					335:339	two types	331:339	two types of modified cellulose (CT and CTCD)	331:375	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	39	theme	coffee	273:278	arg1	grounds					280:286	coffee grounds	273:286	coffee grounds (CG)	273:291	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	9	40	theme	wastewater	1528:1537	arg1	samples					1539:1545	real wastewater samples	1523:1545	real wastewater samples	1523:1545	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	6	41	from	high	1159:1162	arg1	case					1172:1175	each case	1167:1175	each case ranging from 1092.24 to 1220.40 mg g-1	1167:1214	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	5	42	theme	pseudo	1014:1019	arg1	model					1033:1037	pseudo first-order model	1014:1037	pseudo first-order model	1014:1037	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	0	43	theme	sorption	108:115	arg1	capacity					117:124	the highest sorption capacity	96:124	the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development	96:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	2	44	from	morphology	514:523	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	45	from	composition	501:511	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	0	46	theme	cationic	129:136	arg1	dyes					138:141	cationic dyes	129:141	cationic dyes in accordance with the principles of sustainable development	129:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	7	47	theme	materials	1271:1279	arg1	capacity					1242:1249	the adsorption capacity	1227:1249	the adsorption capacity of the near-natural materials	1227:1279	Moreover, the adsorption capacity of the near-natural materials remained even higher after five regeneration cycles.					
35850070	1	48	from	removal	460:466	arg1	wastewater					485:494	the wastewater	481:494	the wastewater	481:494	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	2	49	from	presence	530:537	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	50	attach	presence	530:537	arg2	groups					553:558	functional groups	542:558	functional groups	542:558	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	50	attach	presence	530:537	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	51	theme	groups	553:558	arg1	morphology					514:523	morphology	514:523	morphology	514:523	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	51	theme	groups	553:558	arg1	presence					530:537	presence	530:537	presence	530:537	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	2	51	theme	groups	553:558	arg1	composition					501:511	composition	501:511	composition	501:511	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	7	52	theme	regeneration	1313:1324	arg1	cycles					1326:1331	five regeneration cycles	1308:1331	five regeneration cycles	1308:1331	Moreover, the adsorption capacity of the near-natural materials remained even higher after five regeneration cycles.					
35850070	2	53	theme	sorption	576:583	arg1	materials					585:593	the obtained sorption materials	563:593	the obtained sorption materials	563:593	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	6	54	theme	adsorption	1127:1136	arg1	capacities					1138:1147	the maximum adsorption capacities	1115:1147	the maximum adsorption capacities	1115:1147	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	6	54	theme	adsorption	1127:1136	arg1	high					1159:1162	high	1159:1162	high	1159:1162	According to the Langmuir and Sips isotherm models, the maximum adsorption capacities were very high in each case ranging from 1092.24 to 1220.40 mg g-1.					
35850070	0	55	theme	dyes	138:141	arg1	capacity					117:124	the highest sorption capacity	96:124	the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development	96:202	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	1	56	theme	modified	344:351	arg1	cellulose					353:361	modified cellulose	344:361	modified cellulose (CT and CTCD)	344:375	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	3	57	theme	crystal	722:728	arg1	CV					738:739	CV	738:739	CV	738:739	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	3	57	theme	crystal	722:728	arg1	contaminant					709:719	the model contaminant	699:719	the model contaminant	699:719	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	3	57	theme	crystal	722:728	arg1	violet					730:735	crystal violet	722:735	crystal violet (CV)	722:740	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
35850070	1	58	link	cross-linked	382:393	arg1	β-cyclodextrin					395:408	cross-linked β-cyclodextrin	382:408	cross-linked β-cyclodextrin (CD-1 and CD-2)	382:424	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	58	link	cross-linked	382:393	arg1	adsorbents					441:450	adsorbents	441:450	adsorbents	441:450	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	5	59	theme	second-order	978:989	arg1	model					991:995	a two-model, pseudo second-order model	958:995	a two-model, pseudo second-order model (CG and CGC)	958:1008	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	1	60	theme	cellulose	353:361	arg1	grounds					280:286	coffee grounds	273:286	coffee grounds (CG)	273:291	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	1	60	theme	cellulose	353:361	arg1	types					335:339	two types	331:339	two types of modified cellulose (CT and CTCD)	331:375	In this study, seven different materials were analyzed and includes coffee grounds (CG), two types of cellulose (CGC and CC), two types of modified cellulose (CT and CTCD), and cross-linked β-cyclodextrin (CD-1 and CD-2) were tested as adsorbents for the removal of dyes from the wastewater.					
35850070	9	61	theme	complete	1452:1459	arg1	removal					1461:1467	almost complete removal	1445:1467	almost complete removal of cationic dyes	1445:1484	In addition, almost complete removal of cationic dyes was observed during the treatment of real wastewater samples.					
35850070	5	62	theme	rest	1046:1049	arg1	adsorbents					1051:1060	the rest adsorbents	1042:1060	the rest adsorbents	1042:1060	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	0	63	from	derivatives	18:28	arg1	race					87:90	the race	83:90	the race	83:90	Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development.					
35850070	5	64	dep	model	991:995	arg1	CGC					1005:1007	CGC	1005:1007	CGC	1005:1007	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	5	64	dep	model	991:995	arg1	CG					998:999	CG	998:999	CG	998:999	The time evolution was adjusted using a two-model, pseudo second-order model (CG and CGC) and pseudo first-order model in the rest adsorbents.					
35850070	2	65	theme	elemental	617:625	arg1	analysis					627:634	elemental analysis	617:634	elemental analysis	617:634	The composition, morphology, and presence of functional groups in the obtained sorption materials were characterized by elemental analysis, SEM, TG/DTA, and FTIR spectroscopy.					
35850070	3	66	theme	sorption	677:684	arg1	processes					686:694	The sorption processes	673:694	The sorption processes of the model contaminant, crystal violet (CV),	673:741	The sorption processes of the model contaminant, crystal violet (CV), were studied by kinetics and equilibrium models.					
36184140	6	0	theme	near	1072:1075	arg1	times					1081:1085	near 2.2 times	1072:1085	near 2.2 times higher in comparison with its performance in dark conditions	1072:1146	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	4	1	theme	alginate	740:747	arg1	beads					749:753	alginate beads	740:753	alginate beads loaded with bimetallic nanoparticles	740:790	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	1	2	theme	hybrid	165:170	arg1	materials					172:180	hybrid materials	165:180	hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	165:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	4	3	theme	kinetic	827:833	arg1	kapp					845:848	kapp	845:848	kapp	845:848	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	4	3	theme	kinetic	827:833	arg1	constant					835:842	a 5.4-fold higher apparent kinetic constant	800:842	a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts	800:884	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	1	4	theme	hydrogel	280:287	arg1	beads					289:293	organic bio-based hydrogel beads	262:293	organic bio-based hydrogel beads	262:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	6	5	from	performance	1117:1127	arg1	conditions					1137:1146	dark conditions	1132:1146	dark conditions	1132:1146	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	1	6	theme	materials	172:180	arg1	series					155:160	a series	153:160	a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	153:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	4	7	theme	apparent	818:825	arg1	kapp					845:848	kapp	845:848	kapp	845:848	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	4	7	theme	apparent	818:825	arg1	constant					835:842	a 5.4-fold higher apparent kinetic constant	800:842	a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts	800:884	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	6	8	theme	catalysts	1046:1054	arg1	activity					1030:1037	The activity	1026:1037	The activity of the catalysts	1026:1054	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	4	9	theme	higher	811:816	arg1	kapp					845:848	kapp	845:848	kapp	845:848	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	4	9	theme	higher	811:816	arg1	constant					835:842	a 5.4-fold higher apparent kinetic constant	800:842	a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts	800:884	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	1	10	dep	synthesis	97:105	arg1	the					93:95	the	93:95	the	93:95	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	3	11	dep	reconstruction	631:644	arg1	scan					626:629	scan	626:629	scan	626:629	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	5	12	theme	plasmonic	925:933	arg1	properties					935:944	the plasmonic properties	921:944	the plasmonic properties given by the nanoparticles	921:971	Additionally, taking advantage of the plasmonic properties given by the nanoparticles is that the materials were tested as photocatalysts.					
36184140	6	13	theme	dark	1132:1135	arg1	conditions					1137:1146	dark conditions	1132:1146	dark conditions	1132:1146	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	0	14	theme	CuAu	0:3	arg1	catalysts					35:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts supported on alginate biohydrogels.					
36184140	0	15	theme	bimetallic	5:14	arg1	catalysts					35:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts supported on alginate biohydrogels.					
36184140	1	16	theme	inorganic	194:202	arg1	nanoparticles					235:247	inorganic plasmonic mono- and bimetallic nanoparticles	194:247	inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	194:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	2	17	theme	systems	472:478	arg1	composition					445:455	the metal composition	435:455	the metal composition of the alloyed systems	435:478	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	6	18	with	comparison	1097:1106	arg1	performance					1117:1127	its performance	1113:1127	its performance in dark conditions	1113:1146	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	2	19	theme	plasmon	348:354	arg1	resonance					356:364	a localized surface plasmon resonance	328:364	a localized surface plasmon resonance	328:364	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	1	20	theme	plasmonic	204:212	arg1	nanoparticles					235:247	inorganic plasmonic mono- and bimetallic nanoparticles	194:247	inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	194:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	2	21	theme	alloyed	464:470	arg1	systems					472:478	the alloyed systems	460:478	the alloyed systems	460:478	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	2	22	theme	surface	340:346	arg1	resonance					356:364	a localized surface plasmon resonance	328:364	a localized surface plasmon resonance	328:364	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	1	23	theme	mono-	214:218	arg1	nanoparticles					235:247	inorganic plasmonic mono- and bimetallic nanoparticles	194:247	inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	194:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	0	24	theme	plasmonic-enhanced	16:33	arg1	catalysts					35:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts	0:43	CuAu bimetallic plasmonic-enhanced catalysts supported on alginate biohydrogels.					
36184140	2	25	theme	localized	330:338	arg1	resonance					356:364	a localized surface plasmon resonance	328:364	a localized surface plasmon resonance	328:364	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	1	26	theme	series	155:160	arg1	characterization					108:123	characterization	108:123	characterization	108:123	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	1	26	theme	series	155:160	arg1	properties					139:148	catalytic properties	129:148	catalytic properties	129:148	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	1	26	theme	series	155:160	arg1	synthesis					97:105	synthesis	97:105	synthesis	97:105	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	2	27	theme	metal	439:443	arg1	composition					445:455	the metal composition	435:455	the metal composition of the alloyed systems	435:478	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	4	28	theme	monometallic	860:871	arg1	counterparts					873:884	its monometallic counterparts	856:884	its monometallic counterparts	856:884	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	2	29	theme	light	404:408	arg1	absorption					410:419	a maximum light absorption	394:419	a maximum light absorption correlated to the metal composition of the alloyed systems	394:478	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	1	30	theme	bimetallic	224:233	arg1	nanoparticles					235:247	inorganic plasmonic mono- and bimetallic nanoparticles	194:247	inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads	194:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	3	31	theme	samples	661:667	arg1	reconstruction					631:644	μCT scan reconstruction	622:644	μCT scan reconstruction of lyophilized samples	622:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	3	32	theme	μCT	622:624	arg1	reconstruction					631:644	μCT scan reconstruction	622:644	μCT scan reconstruction of lyophilized samples	622:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	4	33	theme	Catalytic	670:678	arg1	essays					680:685	Catalytic essays	670:685	Catalytic essays for the reduction of 4-nitrophenol	670:720	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	1	34	theme	catalytic	129:137	arg1	properties					139:148	catalytic properties	129:148	catalytic properties	129:148	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	0	35	theme	alginate	58:65	arg1	biohydrogels					67:78	alginate biohydrogels	58:78	alginate biohydrogels	58:78	CuAu bimetallic plasmonic-enhanced catalysts supported on alginate biohydrogels.					
36184140	3	36	with	agreement	575:583	arg1	free-volume					594:604	the free-volume	590:604	the free-volume calculated from μCT scan reconstruction of lyophilized samples	590:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	2	37	theme	visible	373:379	arg1	region					381:386	the visible region	369:386	the visible region	369:386	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	5	38	theme	properties	935:944	arg1	advantage					908:916	advantage	908:916	advantage of the plasmonic properties given by the nanoparticles	908:971	Additionally, taking advantage of the plasmonic properties given by the nanoparticles is that the materials were tested as photocatalysts.					
36184140	4	39	theme	4-nitrophenol	708:720	arg1	reduction					695:703	the reduction	691:703	the reduction of 4-nitrophenol	691:720	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	3	40	theme	total	519:523	arg1	content					531:537	a total water content	517:537	a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples	517:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	3	41	theme	good	570:573	arg1	agreement					575:583	good agreement	570:583	good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples	570:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	2	42	theme	bimetallic	300:309	arg1	materials					311:319	The bimetallic materials	296:319	The bimetallic materials	296:319	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	3	43	theme	lyophilized	649:659	arg1	samples					661:667	lyophilized samples	649:667	lyophilized samples	649:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	3	44	theme	water	525:529	arg1	content					531:537	a total water content	517:537	a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples	517:667	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	4	45	theme	bimetallic	767:776	arg1	nanoparticles					778:790	bimetallic nanoparticles	767:790	bimetallic nanoparticles	767:790	Catalytic essays for the reduction of 4-nitrophenol demonstrated that alginate beads loaded with bimetallic nanoparticles exhibit a 5.4-fold higher apparent kinetic constant (kapp) than its monometallic counterparts.					
36184140	6	46	theme	higher	1087:1092	arg1	times					1081:1085	near 2.2 times	1072:1085	near 2.2 times higher in comparison with its performance in dark conditions	1072:1146	The activity of the catalysts was enhanced by near 2.2 times higher in comparison with its performance in dark conditions.					
36184140	3	47	theme	Thermogravimetric	481:497	arg1	analysis					499:506	Thermogravimetric analysis	481:506	Thermogravimetric analysis	481:506	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	2	48	theme	maximum	396:402	arg1	absorption					410:419	a maximum light absorption	394:419	a maximum light absorption correlated to the metal composition of the alloyed systems	394:478	The bimetallic materials showed a localized surface plasmon resonance in the visible region, with a maximum light absorption correlated to the metal composition of the alloyed systems.					
36184140	1	49	theme	organic	262:268	arg1	beads					289:293	organic bio-based hydrogel beads	262:293	organic bio-based hydrogel beads	262:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
36184140	3	50	theme	w/w	552:554	arg1	%					550:550	90 % w/w	547:554	90 % w/w	547:554	Thermogravimetric analysis revealed a total water content near to 90 % w/w, which was in good agreement with the free-volume calculated from μCT scan reconstruction of lyophilized samples.					
36184140	1	51	theme	bio-based	270:278	arg1	beads					289:293	organic bio-based hydrogel beads	262:293	organic bio-based hydrogel beads	262:293	We describe the synthesis, characterization and catalytic properties of a series of hybrid materials composed of inorganic plasmonic mono- and bimetallic nanoparticles supported on organic bio-based hydrogel beads.					
37182632	2	0	dep	concentrations	320:333	arg1	3					336:336	3	336:336	3	336:336	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	2	0	dep	concentrations	320:333	arg1	%					350:350	9 wt%	346:350	9 wt%	346:350	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	2	0	dep	concentrations	320:333	arg1	6					339:339	6	339:339	6	339:339	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	0	1	theme	trioxide	107:114	arg1	microbicidal					21:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	0	1	theme	trioxide	107:114	arg1	evaluation					48:57	catalytic evaluation	38:57	catalytic evaluation	38:57	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	3	2	theme	different	494:502	arg1	structure					504:512	their different structure	488:512	their different structure	488:512	PVP/CS polymers showed attractive attention because of their different structure, functionality, and architecture control as dopant to WO3.					
37182632	6	3	from	caliper	1187:1193	arg1	mm					1198:1199	mm	1198:1199	mm	1198:1199	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	0	4	theme	evidential	132:141	arg1	analysis					153:160	evidential in-silico analysis	132:160	evidential in-silico analysis	132:160	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	6	5	dep	coli	1103:1106	arg1	coli					1112:1115	E. coli	1109:1115	E. coli	1109:1115	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	4	6	theme	electron-hole	716:728	arg1	issues					736:741	the recombination electron-hole pairs issues	698:741	the recombination electron-hole pairs issues	698:741	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	5	7	dep	efficiency	898:907	arg1	depletion					937:945	dye depletion	933:945	dye depletion	933:945	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	2	8	theme	Various	312:318	arg1	concentrations					320:333	Various concentrations	312:333	Various concentrations (3, 6, and 9 wt%) of PVP	312:358	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	1	9	theme	synthesized	196:206	arg1	nanocomposites					232:245	hydrothermally synthesized tungsten trioxide (WO3) nanocomposites	181:245	hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS)	181:296	In this research, hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS) were studied.					
37182632	6	10	theme	coli	1103:1106	arg1	pathogen					1118:1125	Escherichia coli (E. coli) pathogen	1091:1125	Escherichia coli (E. coli) pathogen	1091:1125	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	4	11	theme	gap	664:666	arg1	reduction					668:676	band gap reduction	659:676	band gap reduction	659:676	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	11	theme	gap	664:666	arg1	size					653:656	crystallite size	641:656	crystallite size (band gap reduction)	641:677	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	12	theme	antimicrobial	812:824	arg1	activity					826:833	improved catalytic and antimicrobial activity	789:833	activity	826:833	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	13	theme	ternary	606:612	arg1	WO3					601:603	the WO3	597:603	the WO3 (ternary composite)	597:623	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	13	theme	ternary	606:612	arg1	composite					614:622	ternary composite	606:622	ternary composite	606:622	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	6	14	theme	high	1138:1141	arg1	concentrations					1143:1156	low and high concentrations	1130:1156	low and high concentrations	1130:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	7	15	theme	PVP/CS-doped	1285:1296	arg1	nanostructures					1302:1315	PVP/CS-doped WO3 nanostructures	1285:1315	PVP/CS-doped WO3 nanostructures	1285:1315	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	1	16	theme	trioxide	217:224	arg1	nanocomposites					232:245	hydrothermally synthesized tungsten trioxide (WO3) nanocomposites	181:245	hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS)	181:296	In this research, hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS) were studied.					
37182632	0	17	theme	in-silico	143:151	arg1	analysis					153:160	evidential in-silico analysis	132:160	evidential in-silico analysis	132:160	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	2	18	theme	nanocomposites	417:430	arg1	nanocomposites					417:430	binary system (CS-WO3) nanocomposites	394:430	binary system (CS-WO3) nanocomposites	394:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	2	18	theme	nanocomposites	417:430	arg1	amount					384:389	a fixed amount	376:389	a fixed amount of binary system (CS-WO3) nanocomposites	376:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	6	19	theme	produced	1059:1066	arg1	nanostructures					1068:1081	Antimicrobial effectiveness of produced nanostructures	1028:1081	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations	1028:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	5	20	theme	synthesized	840:850	arg1	nanocomposites					852:865	The synthesized nanocomposites	836:865	The synthesized nanocomposites	836:865	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	0	21	theme	synergistic	9:19	arg1	microbicidal					21:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	6	22	theme	low	1130:1132	arg1	concentrations					1143:1156	low and high concentrations	1130:1156	low and high concentrations	1130:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	6	23	theme	of	1056:1057	arg1	nanostructures					1068:1081	Antimicrobial effectiveness of produced nanostructures	1028:1081	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations	1028:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	4	24	theme	recombination	702:714	arg1	issues					736:741	the recombination electron-hole pairs issues	698:741	the recombination electron-hole pairs issues	698:741	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	6	25	from	concentrations	1143:1156	arg1	nanostructures					1068:1081	Antimicrobial effectiveness of produced nanostructures	1028:1081	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations	1028:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	6	26	theme	Antimicrobial	1028:1040	arg1	nanostructures					1068:1081	Antimicrobial effectiveness of produced nanostructures	1028:1081	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations	1028:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	0	27	theme	In-vitro	0:7	arg1	microbicidal					21:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal	0:32	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	5	28	theme	dye	933:935	arg1	depletion					937:945	dye depletion	933:945	dye depletion	933:945	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	4	29	theme	crystallite	641:651	arg1	reduction					668:676	band gap reduction	659:676	band gap reduction	659:676	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	29	theme	crystallite	641:651	arg1	size					653:656	crystallite size	641:656	crystallite size (band gap reduction)	641:677	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	2	30	theme	CS-WO3	409:414	arg1	nanocomposites					417:430	binary system (CS-WO3) nanocomposites	394:430	binary system (CS-WO3) nanocomposites	394:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	3	31	dep	structure	504:512	arg1	control					547:553	control	547:553	control	547:553	PVP/CS polymers showed attractive attention because of their different structure, functionality, and architecture control as dopant to WO3.					
37182632	2	32	theme	system	401:406	arg1	nanocomposites					417:430	binary system (CS-WO3) nanocomposites	394:430	binary system (CS-WO3) nanocomposites	394:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	1	33	theme	tungsten	208:215	arg1	WO3					227:229	WO3	227:229	WO3	227:229	In this research, hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS) were studied.					
37182632	1	33	theme	tungsten	208:215	arg1	trioxide					217:224	tungsten trioxide	208:224	hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS)	181:296	In this research, hydrothermally synthesized tungsten trioxide (WO3) nanocomposites doped polyvinylpyrrolidone (PVP) and chitosan (CS) were studied.					
37182632	2	34	theme	binary	394:399	arg1	nanocomposites					417:430	binary system (CS-WO3) nanocomposites	394:430	binary system (CS-WO3) nanocomposites	394:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	7	35	theme	WO3	1298:1300	arg1	nanostructures					1302:1315	PVP/CS-doped WO3 nanostructures	1285:1315	PVP/CS-doped WO3 nanostructures	1285:1315	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	0	36	theme	catalytic	38:46	arg1	evaluation					48:57	catalytic evaluation	38:57	catalytic evaluation	38:57	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	7	37	theme	nanostructures	1302:1315	arg1	experiments					1253:1263	docking experiments	1245:1263	docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli	1245:1353	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	5	38	dep	revealed	867:874	arg1	NaBH4					992:996	NaBH4	992:996	NaBH4	992:996	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	3	39	theme	PVP/CS	433:438	arg1	polymers					440:447	PVP/CS polymers	433:447	PVP/CS polymers	433:447	PVP/CS polymers showed attractive attention because of their different structure, functionality, and architecture control as dopant to WO3.					
37182632	0	40	theme	polyvinylpyrrolidone/chitosan	62:90	arg1	trioxide					107:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	5	41	theme	significant	876:886	arg1	efficiency					898:907	significant catalytic efficiency	876:907	significant catalytic efficiency	876:907	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	5	42	theme	%	955:955	arg1	efficiency					898:907	significant catalytic efficiency	876:907	significant catalytic efficiency	876:907	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	5	42	theme	%	955:955	arg1	methylene					913:921	methylene blue	913:926	methylene blue (MB)	913:931	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	5	42	theme	%	955:955	arg1	MB					929:930	MB	929:930	MB	929:930	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	7	43	theme	docking	1245:1251	arg1	experiments					1253:1263	docking experiments	1245:1263	docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli	1245:1353	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	7	44	theme	enzymes	1387:1393	arg1	pathway					1412:1418	the plausible pathway	1398:1418	the plausible pathway	1398:1418	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	7	44	theme	enzymes	1387:1393	arg1	blockage					1365:1372	blockage	1365:1372	blockage of aforesaid enzymes	1365:1393	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	2	45	theme	fixed	378:382	arg1	nanocomposites					417:430	binary system (CS-WO3) nanocomposites	394:430	binary system (CS-WO3) nanocomposites	394:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	2	45	theme	fixed	378:382	arg1	amount					384:389	a fixed amount	376:389	a fixed amount of binary system (CS-WO3) nanocomposites	376:430	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37182632	5	46	theme	neutral	1002:1008	arg1	media					1021:1025	neutral and acidic media	1002:1025	neutral and acidic media	1002:1025	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	7	47	theme	coli	1350:1353	arg1	FabI					1330:1333	FabI	1330:1333	FabI	1330:1333	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	7	47	theme	coli	1350:1353	arg1	DHFR					1321:1324	DHFR	1321:1324	DHFR	1321:1324	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	5	48	theme	blue	923:926	arg1	methylene					913:921	methylene blue	913:926	methylene blue (MB)	913:931	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	5	48	theme	blue	923:926	arg1	MB					929:930	MB	929:930	MB	929:930	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	7	49	theme	microbicidal	1224:1235	arg1	action					1237:1242	their microbicidal action	1218:1242	their microbicidal action	1218:1242	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	4	50	theme	active	762:767	arg1	sites					769:773	the active sites	758:773	the active sites	758:773	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	3	51	theme	attractive	456:465	arg1	attention					467:475	attractive attention	456:475	attractive attention	456:475	PVP/CS polymers showed attractive attention because of their different structure, functionality, and architecture control as dopant to WO3.					
37182632	4	52	theme	pairs	730:734	arg1	issues					736:741	the recombination electron-hole pairs issues	698:741	the recombination electron-hole pairs issues	698:741	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	7	53	theme	aforesaid	1377:1385	arg1	enzymes					1387:1393	aforesaid enzymes	1377:1393	aforesaid enzymes	1377:1393	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	7	54	theme	plausible	1402:1410	arg1	pathway					1412:1418	the plausible pathway	1398:1418	the plausible pathway	1398:1418	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	7	54	theme	plausible	1402:1410	arg1	blockage					1365:1372	blockage	1365:1372	blockage of aforesaid enzymes	1365:1393	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	5	55	theme	acidic	1014:1019	arg1	media					1021:1025	neutral and acidic media	1002:1025	neutral and acidic media	1002:1025	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	6	56	theme	Vernier	1179:1185	arg1	caliper					1187:1193	Vernier caliper	1179:1193	Vernier caliper in mm	1179:1199	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	5	57	theme	catalytic	888:896	arg1	efficiency					898:907	significant catalytic efficiency	876:907	significant catalytic efficiency	876:907	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	0	58	theme	tungsten	98:105	arg1	trioxide					107:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	7	59	theme	CS-doped	1268:1275	arg1	WO3					1277:1279	CS-doped WO3	1268:1279	CS-doped WO3	1268:1279	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	5	60	theme	reducing	976:983	arg1	agent					985:989	reducing agent	976:989	reducing agent	976:989	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	7	61	theme	WO3	1277:1279	arg1	experiments					1253:1263	docking experiments	1245:1263	docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli	1245:1353	Furthermore, to their microbicidal action, docking experiments of CS-doped WO3 and PVP/CS-doped WO3 nanostructures for DHFR and FabI of Escherichia coli suggested blockage of aforesaid enzymes as the plausible pathway.					
37182632	4	62	theme	band	659:662	arg1	reduction					668:676	band gap reduction	659:676	band gap reduction	659:676	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	4	62	theme	band	659:662	arg1	size					653:656	crystallite size	641:656	crystallite size (band gap reduction)	641:677	The PVP/CS encapsulates the WO3 (ternary composite), which controls crystallite size (band gap reduction), rapidly overcomes the recombination electron-hole pairs issues, and generates the active sites, resulting in improved catalytic and antimicrobial activity.					
37182632	6	63	theme	effectiveness	1042:1054	arg1	nanostructures					1068:1081	Antimicrobial effectiveness of produced nanostructures	1028:1081	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations	1028:1156	Antimicrobial effectiveness of produced nanostructures towards Escherichia coli (E. coli) pathogen at low and high concentrations were investigated by Vernier caliper in mm.					
37182632	0	64	theme	doped	92:96	arg1	trioxide					107:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	polyvinylpyrrolidone/chitosan doped tungsten trioxide	62:114	In-vitro synergistic microbicidal and catalytic evaluation of polyvinylpyrrolidone/chitosan doped tungsten trioxide nanoplates with evidential in-silico analysis.					
37182632	5	65	theme	agent	985:989	arg1	presence					964:971	the presence	960:971	the presence of reducing agent	960:989	The synthesized nanocomposites revealed significant catalytic efficiency and methylene blue (MB) dye depletion of 99.9 % in the presence of reducing agent (NaBH4) in neutral and acidic media.					
37182632	2	66	theme	PVP	356:358	arg1	concentrations					320:333	Various concentrations	312:333	Various concentrations (3, 6, and 9 wt%) of PVP	312:358	Various concentrations (3, 6, and 9 wt%) of PVP were doped into a fixed amount of binary system (CS-WO3) nanocomposites.					
37126959	6	0	from	phases	1031:1036	arg1	forms					1059:1063	the forms	1055:1063	the forms of quartz and whewellite	1055:1088	Calcium and silicon reported to be in crystalline phases respectively, in the forms of quartz and whewellite.					
37126959	6	1	theme	crystalline	1019:1029	arg1	phases					1031:1036	crystalline phases	1019:1036	crystalline phases respectively	1019:1049	Calcium and silicon reported to be in crystalline phases respectively, in the forms of quartz and whewellite.					
37126959	1	2	theme	severe	251:256	arg1	impacts					272:278	severe environmental impacts	251:278	severe environmental impacts	251:278	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	7	3	theme	cassava	1164:1170	arg1	peel					1172:1175	cassava peel	1164:1175	cassava peel	1164:1175	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	3	4	theme	potential	506:514	arg1	utilisation					516:526	potential utilisation	506:526	potential utilisation as alternative biodegradable food packaging matrices	506:579	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	1	5	theme	environmental	258:270	arg1	impacts					272:278	severe environmental impacts	251:278	severe environmental impacts	251:278	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	7	6	theme	potential	1138:1146	arg1	matrices					1214:1221	matrices	1214:1221	matrices for biodegradable food packaging	1214:1254	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	7	6	theme	potential	1138:1146	arg1	valorisation					1148:1159	the potential valorisation	1134:1159	the potential valorisation of cassava peel and bagasse with special interest	1134:1209	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	2	7	theme	food	355:358	arg1	packaging					360:368	biodegradable food packaging	341:368	biodegradable food packaging	341:368	However, these can be raw materials for biodegradable food packaging.					
37126959	3	8	theme	food	557:560	arg1	matrices					572:579	alternative biodegradable food packaging matrices	531:579	alternative biodegradable food packaging matrices	531:579	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	4	9	from	starches	609:616	arg1	peel					629:632	cassava peel	621:632	cassava peel	621:632	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	4	9	from	starches	609:616	arg1	bagasse					638:644	bagasse	638:644	bagasse	638:644	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	3	10	theme	packaging	562:570	arg1	matrices					572:579	alternative biodegradable food packaging matrices	531:579	alternative biodegradable food packaging matrices	531:579	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	0	11	theme	fibrous	100:106	arg1	wastes					124:129	starch-rich fibrous agro-industrial wastes	88:129	starch-rich fibrous agro-industrial wastes for biodegradable food packaging	88:162	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	3	12	dep	morphological	392:404	arg1	thermal					417:423	thermal	417:423	thermal	417:423	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	3	12	dep	morphological	392:404	arg1	chemical					407:414	chemical	407:414	chemical	407:414	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	3	13	theme	alternative	531:541	arg1	matrices					572:579	alternative biodegradable food packaging matrices	531:579	alternative biodegradable food packaging matrices	531:579	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	0	14	theme	starch-rich	88:98	arg1	wastes					124:129	starch-rich fibrous agro-industrial wastes	88:129	starch-rich fibrous agro-industrial wastes for biodegradable food packaging	88:162	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	4	15	theme	Residual	600:607	arg1	starches					609:616	Residual starches	600:616	Residual starches in cassava peel and bagasse	600:644	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	3	16	theme	biodegradable	543:555	arg1	matrices					572:579	alternative biodegradable food packaging matrices	531:579	alternative biodegradable food packaging matrices	531:579	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	3	17	theme	crystalline	437:447	arg1	phases					449:454	crystalline phases	437:454	crystalline phases	437:454	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	7	18	theme	beneficial	1097:1106	arg1	characteristics					1108:1122	These beneficial characteristics	1091:1122	These beneficial characteristics	1091:1122	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	6	19	theme	whewellite	1079:1088	arg1	forms					1059:1063	the forms	1055:1063	the forms of quartz and whewellite	1055:1088	Calcium and silicon reported to be in crystalline phases respectively, in the forms of quartz and whewellite.					
37126959	4	20	theme	cassava	699:705	arg1	starch					707:712	commercial cassava starch	688:712	commercial cassava starch	688:712	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	4	21	theme	commercial	688:697	arg1	starch					707:712	commercial cassava starch	688:712	commercial cassava starch	688:712	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	0	22	theme	properties	26:35	arg1	Investigation					0:12	Investigation	0:12	Investigation of critical properties of Cassava (Manihot esculenta)	0:66	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	6	23	theme	quartz	1068:1073	arg1	forms					1059:1063	the forms	1055:1063	the forms of quartz and whewellite	1055:1088	Calcium and silicon reported to be in crystalline phases respectively, in the forms of quartz and whewellite.					
37126959	1	24	theme	fibrous	194:200	arg1	bagasse					182:188	bagasse	182:188	bagasse	182:188	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	24	theme	fibrous	194:200	arg1	wastes					231:236	fibrous, starch-rich agro-industrial wastes	194:236	fibrous, starch-rich agro-industrial wastes	194:236	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	24	theme	fibrous	194:200	arg1	peel					173:176	Cassava peel	165:176	Cassava peel	165:176	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	0	25	theme	critical	17:24	arg1	properties					26:35	critical properties	17:35	critical properties of Cassava (Manihot esculenta)	17:66	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	0	26	theme	agro-industrial	108:122	arg1	wastes					124:129	starch-rich fibrous agro-industrial wastes	88:129	starch-rich fibrous agro-industrial wastes for biodegradable food packaging	88:162	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	1	27	theme	Cassava	165:171	arg1	bagasse					182:188	bagasse	182:188	bagasse	182:188	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	27	theme	Cassava	165:171	arg1	peel					173:176	Cassava peel	165:176	Cassava peel	165:176	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	27	theme	Cassava	165:171	arg1	wastes					231:236	fibrous, starch-rich agro-industrial wastes	194:236	fibrous, starch-rich agro-industrial wastes	194:236	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	3	28	theme	chemical	461:468	arg1	compositions					470:481	chemical compositions	461:481	chemical compositions	461:481	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	0	29	theme	Cassava	40:46	arg1	properties					26:35	critical properties	17:35	critical properties of Cassava (Manihot esculenta)	17:66	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	0	30	theme	biodegradable	135:147	arg1	packaging					154:162	biodegradable food packaging	135:162	biodegradable food packaging	135:162	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	5	31	theme	cassava	892:898	arg1	peel					900:903	cassava peel	892:903	cassava peel (97.1 (2) %)	892:916	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	5	31	theme	cassava	892:898	arg1	%					915:915	97.1 (2) %	906:915	97.1 (2) %	906:915	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	7	32	theme	food	1241:1244	arg1	packaging					1246:1254	biodegradable food packaging	1227:1254	biodegradable food packaging	1227:1254	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	4	33	dep	similar	667:673	arg1	whereas					715:721	whereas	715:721	whereas	715:721	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	1	34	theme	agro-industrial	215:229	arg1	bagasse					182:188	bagasse	182:188	bagasse	182:188	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	34	theme	agro-industrial	215:229	arg1	wastes					231:236	fibrous, starch-rich agro-industrial wastes	194:236	fibrous, starch-rich agro-industrial wastes	194:236	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	1	34	theme	agro-industrial	215:229	arg1	peel					173:176	Cassava peel	165:176	Cassava peel	165:176	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	0	35	theme	Manihot	49:55	arg1	Cassava					40:46	Cassava	40:46	Cassava (Manihot esculenta)	40:66	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	0	35	theme	Manihot	49:55	arg1	esculenta					57:65	Manihot esculenta	49:65	Manihot esculenta	49:65	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	2	36	theme	biodegradable	341:353	arg1	packaging					360:368	biodegradable food packaging	341:368	biodegradable food packaging	341:368	However, these can be raw materials for biodegradable food packaging.					
37126959	0	37	theme	food	149:152	arg1	packaging					154:162	biodegradable food packaging	135:162	biodegradable food packaging	135:162	Investigation of critical properties of Cassava (Manihot esculenta) peel and bagasse as starch-rich fibrous agro-industrial wastes for biodegradable food packaging.					
37126959	5	38	theme	starch	973:978	arg1	presence					961:968	the presence	957:968	the presence of starch	957:978	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	7	39	with	valorisation	1148:1159	arg1	interest					1202:1209	special interest	1194:1209	special interest	1194:1209	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	7	40	theme	biodegradable	1227:1239	arg1	packaging					1246:1254	biodegradable food packaging	1227:1254	biodegradable food packaging	1227:1254	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	4	41	with	similar	667:673	arg1	that					680:683	that	680:683	that	680:683	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	2	42	theme	raw	323:325	arg1	materials					327:335	raw materials	323:335	raw materials	323:335	However, these can be raw materials for biodegradable food packaging.					
37126959	4	43	theme	cassava	621:627	arg1	peel					629:632	cassava peel	621:632	cassava peel	621:632	Residual starches in cassava peel and bagasse were morphologically similar with that of commercial cassava starch, whereas potassium (8570 ± 56 mg/kg), and calcium (5300 ± 147 mg/kg) were highly abounded in peel and bagasse respectively.					
37126959	7	44	theme	peel	1172:1175	arg1	matrices					1214:1221	matrices	1214:1221	matrices for biodegradable food packaging	1214:1254	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	7	44	theme	peel	1172:1175	arg1	valorisation					1148:1159	the potential valorisation	1134:1159	the potential valorisation of cassava peel and bagasse with special interest	1134:1209	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	5	45	theme	α-amylose	867:875	arg1	dihydrate					877:885	α-amylose dihydrate	867:885	α-amylose dihydrate	867:885	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	1	46	dep	fibrous	194:200	arg1	starch-rich					203:213	starch-rich	203:213	starch-rich	203:213	Cassava peel and bagasse are fibrous, starch-rich agro-industrial wastes, which cause severe environmental impacts upon their disposal.					
37126959	5	47	theme	crystalline	848:858	arg1	phase					860:864	The major crystalline phase	838:864	The major crystalline phase	838:864	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	7	48	theme	special	1194:1200	arg1	interest					1202:1209	special interest	1194:1209	special interest	1194:1209	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	3	49	theme	morphological	392:404	arg1	properties					425:434	their morphological, chemical, thermal properties	386:434	their morphological, chemical, thermal properties	386:434	In this study, their morphological, chemical, thermal properties, crystalline phases, and chemical compositions were investigated, and potential utilisation as alternative biodegradable food packaging matrices has been assessed.					
37126959	5	50	theme	major	842:846	arg1	phase					860:864	The major crystalline phase	838:864	The major crystalline phase	838:864	The major crystalline phase, α-amylose dihydrate, for cassava peel (97.1 (2) %) and bagasse (99.0 (3) %) point towards the presence of starch.					
37126959	7	51	theme	bagasse	1181:1187	arg1	matrices					1214:1221	matrices	1214:1221	matrices for biodegradable food packaging	1214:1254	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
37126959	7	51	theme	bagasse	1181:1187	arg1	valorisation					1148:1159	the potential valorisation	1134:1159	the potential valorisation of cassava peel and bagasse with special interest	1134:1209	These beneficial characteristics suggested the potential valorisation of cassava peel and bagasse with special interest as matrices for biodegradable food packaging.					
35045329	8	0	theme	similar	1171:1177	arg1	proteins					1190:1197	similar structural proteins	1171:1197	similar structural proteins	1171:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	6	1	theme	chitin	804:809	arg1	comparable					822:831	comparable	822:831	comparable	822:831	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	6	1	theme	chitin	804:809	arg1	content					811:817	The high chitin content	795:817	The high chitin content	795:817	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	5	2	from	linkages	767:774	arg1	chrysalis					784:792	each chrysalis	779:792	each chrysalis	779:792	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	0	3	theme	Structural	79:88	arg1	Framework					90:98	Common Chitin-Rich Structural Framework	60:98	Common Chitin-Rich Structural Framework for Monarchs and Swallowtails	60:128	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	8	4	theme	CPMAS	1131:1135	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	1	5	theme	specific	268:275	arg1	chemistry					277:285	specific chemistry	268:285	specific chemistry in nature's complex systems	268:313	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	8	6	theme	underlying	1224:1233	arg1	principles					1242:1251	underlying design principles	1224:1251	underlying design principles	1224:1251	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	5	7	theme	present	705:711	arg1	component					694:702	the major polysaccharide component	669:702	the major polysaccharide component	669:702	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	5	7	theme	present	705:711	arg1	Chitin					659:664	Chitin	659:664	Chitin	659:664	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	8	8	theme	13C	1127:1129	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	6	9	theme	insect	866:871	arg1	exoskeletons					873:884	the highest chitin-containing insect exoskeletons	836:884	the highest chitin-containing insect exoskeletons	836:884	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	7	10	theme	chitinases	933:942	arg1	presence					921:928	the presence	917:928	the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis	917:1103	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	8	11	theme	principles	1242:1251	arg1	presence					1212:1219	the presence	1208:1219	the presence of underlying design principles	1208:1251	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	8	12	theme	identical	1117:1125	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	6	13	theme	chitin-containing	848:864	arg1	exoskeletons					873:884	the highest chitin-containing insect exoskeletons	836:884	the highest chitin-containing insect exoskeletons	836:884	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	3	14	theme	Swallowtail	544:554	arg1	butterflies					556:566	Monarch and Swallowtail butterflies	532:566	butterflies	556:566	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	8	15	theme	design	1235:1240	arg1	principles					1242:1251	underlying design principles	1224:1251	underlying design principles	1224:1251	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	6	16	theme	highest	840:846	arg1	exoskeletons					873:884	the highest chitin-containing insect exoskeletons	836:884	the highest chitin-containing insect exoskeletons	836:884	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	3	17	theme	chemical	455:462	arg1	composition					464:474	chemical composition	455:474	chemical composition	455:474	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	8	18	theme	chitin	1265:1270	arg1	partners					1284:1291	chitin and protein partners	1265:1291	partners	1284:1291	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	5	19	theme	major	673:677	arg1	component					694:702	the major polysaccharide component	669:702	the major polysaccharide component	669:702	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	5	19	theme	major	673:677	arg1	Chitin					659:664	Chitin	659:664	Chitin	659:664	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	2	20	theme	butterfly	395:403	arg1	form					405:408	butterfly form	395:408	butterfly form	395:408	The chrysalis exoskeleton is revealed and shed as a caterpillar transitions to butterfly form.					
35045329	0	21	theme	Chemical	0:7	arg1	Composition					23:33	Chemical and Molecular Composition	0:33	Composition	23:33	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	4	22	theme	chrysalis	581:589	arg1	composition					591:601	The chrysalis composition	577:601	The chrysalis composition	577:601	The chrysalis composition was remarkably similar between Monarch and Swallowtail.					
35045329	4	22	theme	chrysalis	581:589	arg1	similar					618:624	similar	618:624	similar	618:624	The chrysalis composition was remarkably similar between Monarch and Swallowtail.					
35045329	5	23	theme	polysaccharide	679:692	arg1	component					694:702	the major polysaccharide component	669:702	the major polysaccharide component	669:702	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	5	23	theme	polysaccharide	679:692	arg1	Chitin					659:664	Chitin	659:664	Chitin	659:664	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	2	24	theme	chrysalis	320:328	arg1	transitions					380:390	a caterpillar transitions	366:390	a caterpillar transitions to butterfly form	366:408	The chrysalis exoskeleton is revealed and shed as a caterpillar transitions to butterfly form.					
35045329	2	24	theme	chrysalis	320:328	arg1	exoskeleton					330:340	The chrysalis exoskeleton	316:340	The chrysalis exoskeleton	316:340	The chrysalis exoskeleton is revealed and shed as a caterpillar transitions to butterfly form.					
35045329	1	25	theme	awe-inspiring	189:201	arg1	metamorphosis					135:147	The metamorphosis	131:147	The metamorphosis of a caterpillar into a butterfly	131:181	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	1	25	theme	awe-inspiring	189:201	arg1	example					203:209	an awe-inspiring example	186:209	an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems	186:313	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	8	26	theme	protein	1276:1282	arg1	partners					1284:1291	chitin and protein partners	1265:1291	partners	1284:1291	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	1	27	from	chemistry	277:285	arg1	systems					307:313	nature's complex systems	290:313	nature's complex systems	290:313	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	7	28	theme	chrysalis	1002:1010	arg1	proteins					1033:1040	cuticular proteins	1023:1040	synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis	970:1103	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	7	28	theme	chrysalis	1002:1010	arg1	remodeling					984:993	remodeling	984:993	remodeling	984:993	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	7	28	theme	chrysalis	1002:1010	arg1	synthesis					970:978	synthesis	970:978	synthesis	970:978	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	0	29	theme	Molecular	13:21	arg1	Composition					23:33	Chemical and Molecular Composition	0:33	Composition	23:33	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	1	30	theme	complex	299:305	arg1	systems					307:313	nature's complex systems	290:313	nature's complex systems	290:313	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	5	31	theme	catechol-type	753:765	arg1	linkages					767:774	catechol-type linkages	753:774	catechol-type linkages in each chrysalis	753:792	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	7	32	theme	Proteomics	887:896	arg1	analyses					898:905	Proteomics analyses	887:905	Proteomics analyses	887:905	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	3	33	theme	solid-state	423:433	arg1	NMR					435:437	solid-state NMR	423:437	solid-state NMR	423:437	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	7	34	theme	cuticular	1023:1031	arg1	proteins					1033:1040	cuticular proteins	1023:1040	synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis	970:1103	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	8	35	theme	NMR	1137:1139	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	3	36	from	composition	464:474	arg1	chrysalides					509:519	the chrysalides	505:519	the chrysalides from which Monarch and Swallowtail butterflies emerged	505:574	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	1	37	theme	extraordinary	218:230	arg1	functions					232:240	extraordinary functions	218:240	extraordinary functions	218:240	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	8	38	theme	proteins	1190:1197	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	0	39	theme	Chrysalis	42:50	arg1	Composition					23:33	Chemical and Molecular Composition	0:33	Composition	23:33	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	8	40	theme	chrysalis	1157:1165	arg1	spectra					1141:1147	The nearly identical 13C CPMAS NMR spectra	1106:1147	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins	1106:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	3	41	from	types	480:484	arg1	chrysalides					509:519	the chrysalides	505:519	the chrysalides from which Monarch and Swallowtail butterflies emerged	505:574	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	8	42	theme	structural	1179:1188	arg1	proteins					1190:1197	similar structural proteins	1171:1197	similar structural proteins	1171:1197	The nearly identical 13C CPMAS NMR spectra of each chrysalis and similar structural proteins supports the presence of underlying design principles integrating chitin and protein partners to elaborate the chrysalis.					
35045329	3	43	dep	composition	464:474	arg1	the					451:453	the	451:453	the	451:453	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	6	44	theme	high	799:802	arg1	comparable					822:831	comparable	822:831	comparable	822:831	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	6	44	theme	high	799:802	arg1	content					811:817	The high chitin content	795:817	The high chitin content	795:817	The high chitin content is comparable to the highest chitin-containing insect exoskeletons.					
35045329	3	45	theme	biomolecules	489:500	arg1	types					480:484	types	480:484	types	480:484	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	3	45	theme	biomolecules	489:500	arg1	composition					464:474	chemical composition	455:474	chemical composition	455:474	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	7	46	theme	chrysalis	1095:1103	arg1	integrity					1078:1086	the structural integrity	1063:1086	the structural integrity of the chrysalis	1063:1103	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	1	47	theme	caterpillar	154:164	arg1	metamorphosis					135:147	The metamorphosis	131:147	The metamorphosis of a caterpillar into a butterfly	131:181	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	1	47	theme	caterpillar	154:164	arg1	example					203:209	an awe-inspiring example	186:209	an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems	186:313	The metamorphosis of a caterpillar into a butterfly is an awe-inspiring example of how extraordinary functions are made possible through specific chemistry in nature's complex systems.					
35045329	5	48	from	catechols	740:748	arg1	chrysalis					784:792	each chrysalis	779:792	each chrysalis	779:792	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35045329	0	49	theme	Chitin-Rich	67:77	arg1	Framework					90:98	Common Chitin-Rich Structural Framework	60:98	Common Chitin-Rich Structural Framework for Monarchs and Swallowtails	60:128	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	7	50	theme	structural	1067:1076	arg1	integrity					1078:1086	the structural integrity	1063:1086	the structural integrity of the chrysalis	1063:1103	Proteomics analyses indicated the presence of chitinases that could be involved in synthesis and remodeling of the chrysalis as well as cuticular proteins which play a role in the structural integrity of the chrysalis.					
35045329	3	51	theme	Monarch	532:538	arg1	butterflies					556:566	Monarch and Swallowtail butterflies	532:566	butterflies	556:566	We employed solid-state NMR to evaluate the chemical composition and types of biomolecules in the chrysalides from which Monarch and Swallowtail butterflies emerged.					
35045329	0	52	theme	Common	60:65	arg1	Framework					90:98	Common Chitin-Rich Structural Framework	60:98	Common Chitin-Rich Structural Framework for Monarchs and Swallowtails	60:128	Chemical and Molecular Composition of the Chrysalis Reveals Common Chitin-Rich Structural Framework for Monarchs and Swallowtails.					
35045329	2	53	theme	caterpillar	368:378	arg1	exoskeleton					330:340	The chrysalis exoskeleton	316:340	The chrysalis exoskeleton	316:340	The chrysalis exoskeleton is revealed and shed as a caterpillar transitions to butterfly form.					
35045329	2	53	theme	caterpillar	368:378	arg1	transitions					380:390	a caterpillar transitions	366:390	a caterpillar transitions to butterfly form	366:408	The chrysalis exoskeleton is revealed and shed as a caterpillar transitions to butterfly form.					
35045329	5	54	from	proteins	727:734	arg1	chrysalis					784:792	each chrysalis	779:792	each chrysalis	779:792	Chitin is the major polysaccharide component, present together with proteins and catechols or catechol-type linkages in each chrysalis.					
35367269	0	0	theme	molecules	115:123	arg1	encapsulation					69:81	encapsulation	69:81	encapsulation	69:81	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	0	0	theme	molecules	115:123	arg1	release					98:104	controlled release	87:104	controlled release of scent molecules	87:123	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	7	1	theme	scent	1180:1184	arg1	pattern					1158:1164	a sustained release pattern	1138:1164	a sustained release pattern of the loaded scent	1138:1184	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	7	2	theme	controlled	1025:1034	arg1	microcapsules					1041:1053	controlled size microcapsules	1025:1053	controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process	1025:1129	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	0	3	theme	scent	109:113	arg1	molecules					115:123	scent molecules	109:123	scent molecules	109:123	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	1	4	from	sources	188:194	arg1	foods					166:170	nutritious foods	155:170	nutritious foods from non-animal sources	155:194	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	1	4	from	sources	188:194	arg1	meats					138:142	Plant-based meats	126:142	Plant-based meats	126:142	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	3	5	theme	desirable	549:557	arg1	flavor					569:574	a desirable meat-like flavor	547:574	a desirable meat-like flavor to consumers	547:587	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	8	6	theme	plant-based	1482:1492	arg1	meat					1494:1497	the plant-based meat	1478:1497	the plant-based meat	1478:1497	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	4	7	theme	hybrid	687:692	arg1	hydrogels					694:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	In this study, we prepared thermoresponsive gelatin-alginate hybrid hydrogels to control the release of scent molecules.					
35367269	7	8	theme	loaded	1173:1178	arg1	scent					1180:1184	the loaded scent	1169:1184	the loaded scent	1169:1184	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	8	9	theme	food	1410:1413	arg1	additives					1415:1423	food additives	1410:1423	food additives that can control the release of scent molecules from the plant-based meat during cooking	1410:1512	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	8	10	theme	potential	1357:1365	arg1	use					1367:1369	the potential use	1353:1369	the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking	1353:1512	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	3	11	theme	conventional	517:528	arg1	meat					530:533	conventional meat	517:533	conventional meat	517:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	4	12	theme	scent	730:734	arg1	molecules					736:744	scent molecules	730:744	scent molecules	730:744	In this study, we prepared thermoresponsive gelatin-alginate hybrid hydrogels to control the release of scent molecules.					
35367269	3	13	theme	Plant-based	389:399	arg1	meat					401:404	Plant-based meat	389:404	Plant-based meat	389:404	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	1	14	theme	conventional	269:280	arg1	production					287:296	conventional meat production	269:296	conventional meat production	269:296	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	3	15	theme	scent	490:494	arg1	mechanism					504:512	the scent release mechanism	486:512	the scent release mechanism of conventional meat	486:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	0	16	theme	semi-interpenetrating	17:37	arg1	networks					56:63	semi-interpenetrating gelatin-alginate networks	17:63	semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules	17:123	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	7	17	theme	2-fold	1272:1277	arg1	range					1279:1283	an approximately 2-fold range	1255:1283	an approximately 2-fold range	1255:1283	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	7	18	theme	sustained	1140:1148	arg1	pattern					1158:1164	a sustained release pattern	1138:1164	a sustained release pattern of the loaded scent	1138:1184	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	6	19	theme	sIPN	855:858	arg1	formation					860:868	sIPN formation	855:868	sIPN formation	855:868	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	2	20	theme	rapid	361:365	arg1	growth					367:372	the rapid growth	357:372	the rapid growth of its market	357:386	Interest in plant-based meat has increased and is driving the rapid growth of its market.					
35367269	3	21	theme	similar	475:481	arg1	system					468:473	a temperature-dependent scent release system	430:473	a temperature-dependent scent release system similar to the scent release mechanism of conventional meat	430:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	7	22	theme	extrusion	1113:1121	arg1	process					1123:1129	an electrostatic extrusion process	1096:1129	an electrostatic extrusion process	1096:1129	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	7	23	theme	release	1150:1156	arg1	pattern					1158:1164	a sustained release pattern	1138:1164	a sustained release pattern of the loaded scent	1138:1184	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	1	24	theme	Plant-based	126:136	arg1	foods					166:170	nutritious foods	155:170	nutritious foods from non-animal sources	155:194	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	1	24	theme	Plant-based	126:136	arg1	meats					138:142	Plant-based meats	126:142	Plant-based meats	126:142	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	2	25	from	Interest	299:306	arg1	meat					323:326	plant-based meat	311:326	plant-based meat	311:326	Interest in plant-based meat has increased and is driving the rapid growth of its market.					
35367269	7	26	theme	scent	1204:1208	arg1	rate					1218:1221	the scent release rate	1200:1221	the scent release rate	1200:1221	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	3	27	theme	higher	600:605	arg1	acceptance					614:623	higher market acceptance	600:623	higher market acceptance	600:623	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	6	28	theme	external	894:901	arg1	temperature					947:957	temperature	947:957	temperature	947:957	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	6	28	theme	external	894:901	arg1	force					926:930	shear force	920:930	shear force	920:930	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	6	28	theme	external	894:901	arg1	stimuli					903:909	external stimuli	894:909	external stimuli	894:909	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	6	28	theme	external	894:901	arg1	swelling					933:940	swelling	933:940	swelling	933:940	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	0	29	theme	gelatin-alginate	39:54	arg1	networks					56:63	semi-interpenetrating gelatin-alginate networks	17:63	semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules	17:123	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	3	30	theme	market	607:612	arg1	acceptance					614:623	higher market acceptance	600:623	higher market acceptance	600:623	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	8	31	from	meat	1494:1497	arg1	release					1446:1452	the release	1442:1452	the release of scent molecules from the plant-based meat	1442:1497	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	1	32	theme	negative	230:237	arg1	externalities					239:251	the negative externalities	226:251	the negative externalities associated with conventional meat production	226:296	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	3	33	theme	release	460:466	arg1	system					468:473	a temperature-dependent scent release system	430:473	a temperature-dependent scent release system similar to the scent release mechanism of conventional meat	430:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	6	34	theme	scent	1005:1009	arg1	release					985:991	a sustained release	973:991	a sustained release of the meat scent	973:1009	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	5	35	theme	gelatin-alginate	770:785	arg1	hydrogels					787:795	gelatin-alginate hydrogels	770:795	gelatin-alginate hydrogels	770:795	The polymer network of gelatin-alginate hydrogels was reinforced by a semi-interpenetrating network (sIPN).					
35367269	7	36	theme	alginate	1302:1309	arg1	concentration					1311:1323	the alginate concentration	1298:1323	the alginate concentration	1298:1323	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	8	37	theme	molecules	1463:1471	arg1	release					1446:1452	the release	1442:1452	the release of scent molecules from the plant-based meat	1442:1497	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	3	38	theme	release	496:502	arg1	mechanism					504:512	the scent release mechanism	486:512	the scent release mechanism of conventional meat	486:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	6	39	theme	meat	1000:1003	arg1	scent					1005:1009	the meat scent	996:1009	the meat scent	996:1009	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	5	40	theme	hydrogels	787:795	arg1	network					759:765	The polymer network	747:765	The polymer network of gelatin-alginate hydrogels	747:795	The polymer network of gelatin-alginate hydrogels was reinforced by a semi-interpenetrating network (sIPN).					
35367269	8	41	theme	edible	1374:1379	arg1	macromolecules					1392:1405	edible biological macromolecules	1374:1405	edible biological macromolecules	1374:1405	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	4	42	theme	gelatin-alginate	670:685	arg1	hydrogels					694:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	In this study, we prepared thermoresponsive gelatin-alginate hybrid hydrogels to control the release of scent molecules.					
35367269	0	43	theme	controlled	87:96	arg1	release					98:104	controlled release	87:104	controlled release of scent molecules	87:123	Thermoresponsive semi-interpenetrating gelatin-alginate networks for encapsulation and controlled release of scent molecules.					
35367269	6	44	theme	shear	920:924	arg1	force					926:930	shear force	920:930	shear force	920:930	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	7	45	theme	same	1075:1078	arg1	composition					1080:1090	the same composition	1071:1090	the same composition	1071:1090	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	2	46	theme	market	381:386	arg1	growth					367:372	the rapid growth	357:372	the rapid growth of its market	357:386	Interest in plant-based meat has increased and is driving the rapid growth of its market.					
35367269	3	47	theme	scent	454:458	arg1	system					468:473	a temperature-dependent scent release system	430:473	a temperature-dependent scent release system similar to the scent release mechanism of conventional meat	430:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	7	48	theme	electrostatic	1099:1111	arg1	process					1123:1129	an electrostatic extrusion process	1096:1129	an electrostatic extrusion process	1096:1129	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	8	49	theme	macromolecules	1392:1405	arg1	use					1367:1369	the potential use	1353:1369	the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking	1353:1512	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	2	50	theme	plant-based	311:321	arg1	meat					323:326	plant-based meat	311:326	plant-based meat	311:326	Interest in plant-based meat has increased and is driving the rapid growth of its market.					
35367269	8	51	theme	scent	1457:1461	arg1	molecules					1463:1471	scent molecules	1457:1471	scent molecules	1457:1471	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	1	52	theme	nutritious	155:164	arg1	foods					166:170	nutritious foods	155:170	nutritious foods from non-animal sources	155:194	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	1	52	theme	nutritious	155:164	arg1	meats					138:142	Plant-based meats	126:142	Plant-based meats	126:142	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	5	53	theme	polymer	751:757	arg1	network					759:765	The polymer network	747:765	The polymer network of gelatin-alginate hydrogels	747:795	The polymer network of gelatin-alginate hydrogels was reinforced by a semi-interpenetrating network (sIPN).					
35367269	8	54	theme	biological	1381:1390	arg1	macromolecules					1392:1405	edible biological macromolecules	1374:1405	edible biological macromolecules	1374:1405	These observations suggest the potential use of edible biological macromolecules as food additives that can control the release of scent molecules from the plant-based meat during cooking.					
35367269	7	55	theme	size	1036:1039	arg1	microcapsules					1041:1053	controlled size microcapsules	1025:1053	controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process	1025:1129	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	4	56	theme	molecules	736:744	arg1	release					719:725	the release	715:725	the release of scent molecules	715:744	In this study, we prepared thermoresponsive gelatin-alginate hybrid hydrogels to control the release of scent molecules.					
35367269	3	57	theme	meat	530:533	arg1	mechanism					504:512	the scent release mechanism	486:512	the scent release mechanism of conventional meat	486:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	5	58	theme	semi-interpenetrating	817:837	arg1	network					839:845	a semi-interpenetrating network	815:845	a semi-interpenetrating network (sIPN)	815:852	The polymer network of gelatin-alginate hydrogels was reinforced by a semi-interpenetrating network (sIPN).					
35367269	5	58	theme	semi-interpenetrating	817:837	arg1	sIPN					848:851	sIPN	848:851	sIPN	848:851	The polymer network of gelatin-alginate hydrogels was reinforced by a semi-interpenetrating network (sIPN).					
35367269	3	59	theme	meat-like	559:567	arg1	flavor					569:574	a desirable meat-like flavor	547:574	a desirable meat-like flavor to consumers	547:587	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	1	60	theme	meat	282:285	arg1	production					287:296	conventional meat production	269:296	conventional meat production	269:296	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	3	61	theme	temperature-dependent	432:452	arg1	system					468:473	a temperature-dependent scent release system	430:473	a temperature-dependent scent release system similar to the scent release mechanism of conventional meat	430:533	Plant-based meat should be equipped with a temperature-dependent scent release system similar to the scent release mechanism of conventional meat, to deliver a desirable meat-like flavor to consumers and obtain higher market acceptance.					
35367269	6	62	theme	sustained	975:983	arg1	release					985:991	a sustained release	973:991	a sustained release of the meat scent	973:1009	sIPN formation conferred resistance to external stimuli, such as shear force, swelling, and temperature, resulting in a sustained release of the meat scent.					
35367269	7	63	theme	release	1210:1216	arg1	rate					1218:1221	the scent release rate	1200:1221	the scent release rate	1200:1221	In addition, controlled size microcapsules fabricated from the same composition via an electrostatic extrusion process showed a sustained release pattern of the loaded scent at 70 °C, and the scent release rate was precisely controlled within an approximately 2-fold range by adjusting the alginate concentration.					
35367269	1	64	theme	non-animal	177:186	arg1	sources					188:194	non-animal sources	177:194	non-animal sources	177:194	Plant-based meats, which are nutritious foods from non-animal sources, provide clues for addressing the negative externalities associated with conventional meat production.					
35367269	4	65	theme	thermoresponsive	653:668	arg1	hydrogels					694:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	thermoresponsive gelatin-alginate hybrid hydrogels	653:702	In this study, we prepared thermoresponsive gelatin-alginate hybrid hydrogels to control the release of scent molecules.					
35833511	6	0	theme	hard	959:962	arg1	crowders					964:971	hard crowders	959:971	hard crowders	959:971	However, our simulations indicate that elongated macromolecules, such as double-stranded DNA pieces, can diffuse comparably or even faster in hard crowders.					
35833511	7	1	theme	different	1050:1058	arg1	tracers					1060:1066	different tracers	1050:1066	different tracers	1050:1066	We relate these effects to the volume excluded by soft and hard crowders to different tracers.					
35833511	2	2	theme	composition	356:366	arg1	subdiffusion					297:308	anomalous subdiffusion	287:308	anomalous subdiffusion	287:308	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	2	2	theme	composition	356:366	arg1	effects					319:325	the effects	315:325	the effects of interactions, shapes, and composition	315:366	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	4	3	theme	most	583:586	arg1	cases					588:592	most cases	583:592	most cases	583:592	We find that in most cases, soft crowders slow down the diffusion less effectively than hard crowders like Ficoll.					
35833511	6	4	theme	elongated	856:864	arg1	macromolecules					866:879	elongated macromolecules	856:879	elongated macromolecules	856:879	However, our simulations indicate that elongated macromolecules, such as double-stranded DNA pieces, can diffuse comparably or even faster in hard crowders.					
35833511	6	4	theme	elongated	856:864	arg1	pieces					910:915	double-stranded DNA pieces	890:915	double-stranded DNA pieces	890:915	However, our simulations indicate that elongated macromolecules, such as double-stranded DNA pieces, can diffuse comparably or even faster in hard crowders.					
35833511	8	5	dep	softness	1095:1102	arg1	the					1091:1093	the	1091:1093	the	1091:1093	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	1	6	from	metabolism	166:175	arg1	essential					117:125	essential	117:125	essential	117:125	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	1	7	from	Diffusion	62:70	arg1	environment					102:112	a macromolecularly crowded environment	75:112	a macromolecularly crowded environment	75:112	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	3	8	theme	macromolecular	541:554	arg1	diffusion					556:564	macromolecular diffusion	541:564	macromolecular diffusion	541:564	Herein, we use Brownian dynamics simulations to study how the softness of crowders affects macromolecular diffusion.					
35833511	5	9	theme	occupied	705:712	arg1	fraction					721:728	a 30% occupied volume fraction	699:728	a 30% occupied volume fraction	699:728	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	5	10	theme	volume	714:719	arg1	fraction					721:728	a 30% occupied volume fraction	699:728	a 30% occupied volume fraction	699:728	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	2	11	theme	anomalous	287:295	arg1	subdiffusion					297:308	anomalous subdiffusion	287:308	anomalous subdiffusion	287:308	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	8	12	theme	relevant	1190:1197	arg1	crowding					1180:1187	crowding	1180:1187	crowding	1180:1187	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	4	13	theme	hard	655:658	arg1	crowders					660:667	hard crowders	655:667	hard crowders like Ficoll	655:679	We find that in most cases, soft crowders slow down the diffusion less effectively than hard crowders like Ficoll.					
35833511	1	14	theme	macromolecularly	77:92	arg1	environment					102:112	a macromolecularly crowded environment	75:112	a macromolecularly crowded environment	75:112	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	5	15	theme	size	811:814	arg1	crowders					790:797	soft crowders	785:797	soft crowders of the same size	785:814	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	1	16	theme	crowded	94:100	arg1	environment					102:112	a macromolecularly crowded environment	75:112	a macromolecularly crowded environment	75:112	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	1	17	theme	gene	194:197	arg1	transcription					199:211	gene transcription	194:211	gene transcription	194:211	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	5	18	theme	soft	785:788	arg1	crowders					790:797	soft crowders	785:797	soft crowders of the same size	785:814	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	8	19	theme	macromolecules	1117:1130	arg1	factors					1144:1150	crucial factors	1136:1150	crucial factors determining diffusion under crowding, relevant to diverse intracellular environments	1136:1235	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	8	19	theme	macromolecules	1117:1130	arg1	shape					1108:1112	shape	1108:1112	shape	1108:1112	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	8	19	theme	macromolecules	1117:1130	arg1	softness					1095:1102	softness	1095:1102	softness	1095:1102	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	3	20	theme	crowders	524:531	arg1	softness					512:519	the softness	508:519	the softness of crowders	508:531	Herein, we use Brownian dynamics simulations to study how the softness of crowders affects macromolecular diffusion.					
35833511	3	21	theme	Brownian	465:472	arg1	simulations					483:493	Brownian dynamics simulations	465:493	Brownian dynamics simulations	465:493	Herein, we use Brownian dynamics simulations to study how the softness of crowders affects macromolecular diffusion.					
35833511	2	22	theme	shapes	344:349	arg1	subdiffusion					297:308	anomalous subdiffusion	287:308	anomalous subdiffusion	287:308	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	2	22	theme	shapes	344:349	arg1	effects					319:325	the effects	315:325	the effects of interactions, shapes, and composition	315:366	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	2	23	theme	macromolecules	406:419	arg1	softness					394:401	softness	394:401	softness	394:401	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	2	23	theme	macromolecules	406:419	arg1	compactness					379:389	compactness	379:389	compactness	379:389	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	5	24	theme	same	806:809	arg1	size					811:814	the same size	802:814	the same size	802:814	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	6	25	theme	DNA	906:908	arg1	pieces					910:915	double-stranded DNA pieces	890:915	double-stranded DNA pieces	890:915	However, our simulations indicate that elongated macromolecules, such as double-stranded DNA pieces, can diffuse comparably or even faster in hard crowders.					
35833511	7	26	dep	soft	1024:1027	arg1	crowders					1038:1045	crowders	1038:1045	crowders to different tracers	1038:1066	We relate these effects to the volume excluded by soft and hard crowders to different tracers.					
35833511	2	27	theme	theoretical	238:248	arg1	work					267:270	theoretical and experimental work	238:270	theoretical and experimental work	238:270	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	8	28	theme	intracellular	1210:1222	arg1	environments					1224:1235	diverse intracellular environments	1202:1235	diverse intracellular environments	1202:1235	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	6	29	theme	double-stranded	890:904	arg1	pieces					910:915	double-stranded DNA pieces	890:915	double-stranded DNA pieces	890:915	However, our simulations indicate that elongated macromolecules, such as double-stranded DNA pieces, can diffuse comparably or even faster in hard crowders.					
35833511	8	30	theme	crucial	1136:1142	arg1	factors					1144:1150	crucial factors	1136:1150	crucial factors determining diffusion under crowding, relevant to diverse intracellular environments	1136:1235	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	8	30	theme	crucial	1136:1142	arg1	shape					1108:1112	shape	1108:1112	shape	1108:1112	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	8	30	theme	crucial	1136:1142	arg1	softness					1095:1102	softness	1095:1102	softness	1095:1102	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	5	31	from	diffusion	735:743	arg1	Ficoll70					748:755	Ficoll70	748:755	Ficoll70	748:755	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	1	32	theme	many	131:134	arg1	processes					150:158	many intracellular processes	131:158	many intracellular processes	131:158	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	2	33	dep	compactness	379:389	arg1	the					375:377	the	375:377	the	375:377	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	1	34	theme	intracellular	136:148	arg1	processes					150:158	many intracellular processes	131:158	many intracellular processes	131:158	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	5	35	dep	occupied	705:712	arg1	%					703:703	30%	701:703	30%	701:703	For instance, at a 30% occupied volume fraction, the diffusion in Ficoll70 is about 20% slower than in soft crowders of the same size.					
35833511	2	36	theme	interactions	330:341	arg1	subdiffusion					297:308	anomalous subdiffusion	287:308	anomalous subdiffusion	287:308	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	2	36	theme	interactions	330:341	arg1	effects					319:325	the effects	315:325	the effects of interactions, shapes, and composition	315:366	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	3	37	theme	dynamics	474:481	arg1	simulations					483:493	Brownian dynamics simulations	465:493	Brownian dynamics simulations	465:493	Herein, we use Brownian dynamics simulations to study how the softness of crowders affects macromolecular diffusion.					
35833511	8	38	theme	diverse	1202:1208	arg1	environments					1224:1235	diverse intracellular environments	1202:1235	diverse intracellular environments	1202:1235	Our results show that the softness and shape of macromolecules are crucial factors determining diffusion under crowding, relevant to diverse intracellular environments.					
35833511	4	39	theme	down	614:617	arg1	diffusion					623:631	the diffusion	619:631	slow down the diffusion	609:631	We find that in most cases, soft crowders slow down the diffusion less effectively than hard crowders like Ficoll.					
35833511	2	40	theme	experimental	254:265	arg1	work					267:270	theoretical and experimental work	238:270	theoretical and experimental work	238:270	So far, theoretical and experimental work has focused on anomalous subdiffusion, and the effects of interactions, shapes, and composition, while the compactness or softness of macromolecules has received less attention.					
35833511	1	41	from	catalysis	181:189	arg1	essential					117:125	essential	117:125	essential	117:125	Diffusion in a macromolecularly crowded environment is essential for many intracellular processes, from metabolism and catalysis to gene transcription and translation.					
35833511	4	42	theme	slow	609:612	arg1	diffusion					623:631	the diffusion	619:631	slow down the diffusion	609:631	We find that in most cases, soft crowders slow down the diffusion less effectively than hard crowders like Ficoll.					
35364194	7	0	theme	polymer	1213:1219	arg1	materials					1221:1229	polymer materials	1213:1229	polymer materials	1213:1229	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	6	1	theme	shish-kebab	972:982	arg1	structures					984:993	more PLA shish-kebab structures	963:993	more PLA shish-kebab structures	963:993	At the same time, due to this coupling effect, more PLA shish-kebab structures were induced at the interface.					
35364194	1	2	theme	polylactic	231:240	arg1	acid					242:245	polylactic acid	231:245	polylactic acid (PLA)	231:251	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	1	2	theme	polylactic	231:240	arg1	PLA					248:250	PLA	248:250	PLA	248:250	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	7	3	theme	great	1104:1108	arg1	significance					1110:1121	great significance	1104:1121	great significance	1104:1121	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	1	4	theme	unbalanced	139:148	arg1	properties					161:170	unbalanced mechanical properties	139:170	unbalanced mechanical properties	139:170	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	1	5	theme	acid	242:245	arg1	problems					219:226	two major problems	209:226	two major problems of polylactic acid (PLA)	209:251	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	7	6	theme	materials	1221:1229	arg1	toughness					1200:1208	toughness	1200:1208	toughness	1200:1208	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	7	6	theme	materials	1221:1229	arg1	strength					1187:1194	strength	1187:1194	strength	1187:1194	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	7	7	theme	toughness	1200:1208	arg1	balance					1176:1182	the balance	1172:1182	the balance of strength and toughness of polymer materials	1172:1229	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	4	8	theme	crystallization	792:806	arg1	behavior					808:815	the crystallization behavior	788:815	the crystallization behavior of PLA	788:822	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	7	9	theme	special	1031:1037	arg1	structure					1052:1060	This special hierarchical structure	1026:1060	This special hierarchical structure composed of CNC and PLA Shish-Kebab	1026:1096	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	5	10	theme	shish	848:852	arg1	length					854:859	PLA shish length	844:859	PLA shish length from 251 nm to 889 nm	844:881	CNC could increase PLA shish length from 251 nm to 889 nm under the action of shear field.					
35364194	4	11	theme	field	755:759	arg1	effect					719:724	the coupling effect	706:724	the coupling effect of CNC and strong shear flow field	706:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	6	12	theme	more	963:966	arg1	structures					984:993	more PLA shish-kebab structures	963:993	more PLA shish-kebab structures	963:993	At the same time, due to this coupling effect, more PLA shish-kebab structures were induced at the interface.					
35364194	5	13	theme	PLA	844:846	arg1	length					854:859	PLA shish length	844:859	PLA shish length from 251 nm to 889 nm	844:881	CNC could increase PLA shish length from 251 nm to 889 nm under the action of shear field.					
35364194	1	14	theme	mechanical	150:159	arg1	properties					161:170	unbalanced mechanical properties	139:170	unbalanced mechanical properties	139:170	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	7	15	theme	PLA	1082:1084	arg1	Shish-Kebab					1086:1096	PLA Shish-Kebab	1082:1096	PLA Shish-Kebab	1082:1096	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	4	16	theme	flow	750:753	arg1	field					755:759	strong shear flow field	737:759	strong shear flow field	737:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	0	17	dep	strength	81:88	arg1	the					77:79	the	77:79	the	77:79	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	0	17	dep	strength	81:88	arg1	balance					104:110	balance	104:110	balance	104:110	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	6	18	theme	PLA	968:970	arg1	structures					984:993	more PLA shish-kebab structures	963:993	more PLA shish-kebab structures	963:993	At the same time, due to this coupling effect, more PLA shish-kebab structures were induced at the interface.					
35364194	0	19	theme	coupling	4:11	arg1	effect					13:18	The coupling effect	0:18	The coupling effect of cellulose nanocrystal and strong shear field	0:66	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	2	20	theme	shearing	329:336	arg1	field					338:342	strong shearing field	322:342	strong shearing field	322:342	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	0	21	theme	Polylactide	115:125	arg1	toughness					94:102	toughness	94:102	toughness	94:102	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	0	21	theme	Polylactide	115:125	arg1	strength					81:88	strength	81:88	strength	81:88	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	4	22	theme	strong	737:742	arg1	field					755:759	strong shear flow field	737:759	strong shear flow field	737:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	1	23	theme	heat	181:184	arg1	resistance					186:195	poor heat resistance	176:195	poor heat resistance	176:195	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	3	24	theme	PLA	518:520	arg1	toughness					505:513	the toughness	501:513	the toughness of PLA	501:520	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	4	25	theme	composites	637:646	arg1	microstructure					611:624	The microstructure	607:624	The microstructure of PLA/CNC composites	607:646	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	0	26	theme	nanocrystal	33:43	arg1	effect					13:18	The coupling effect	0:18	The coupling effect of cellulose nanocrystal and strong shear field	0:66	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	7	27	theme	important	1139:1147	arg1	guidance					1149:1156	important guidance	1139:1156	important guidance for achieving the balance of strength and toughness of polymer materials	1139:1229	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	3	28	theme	softening	537:545	arg1	temperature					547:557	the vicat softening temperature	527:557	the vicat softening temperature of DPIM PLA/CNC	527:573	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	1	29	theme	poor	176:179	arg1	resistance					186:195	poor heat resistance	176:195	poor heat resistance	176:195	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	2	30	theme	hierarchical	360:371	arg1	structure					373:381	a unique hierarchical structure	351:381	a unique hierarchical structure	351:381	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	0	31	theme	cellulose	23:31	arg1	nanocrystal					33:43	cellulose nanocrystal	23:43	cellulose nanocrystal	23:43	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	7	32	theme	hierarchical	1039:1050	arg1	structure					1052:1060	This special hierarchical structure	1026:1060	This special hierarchical structure composed of CNC and PLA Shish-Kebab	1026:1096	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	4	33	theme	CNC	729:731	arg1	effect					719:724	the coupling effect	706:724	the coupling effect of CNC and strong shear flow field	706:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	2	34	theme	unique	353:358	arg1	structure					373:381	a unique hierarchical structure	351:381	a unique hierarchical structure	351:381	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	0	35	theme	strong	49:54	arg1	field					62:66	strong shear field	49:66	strong shear field	49:66	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	4	36	theme	PLA	820:822	arg1	behavior					808:815	the crystallization behavior	788:815	the crystallization behavior of PLA	788:822	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	3	37	theme	pure	398:401	arg1	PLA					403:405	pure PLA	398:405	pure PLA	398:405	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	4	38	theme	shear	744:748	arg1	field					755:759	strong shear flow field	737:759	strong shear flow field	737:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	3	39	theme	PLA/CNC	437:443	arg1	strength					420:427	the tensile strength	408:427	the tensile strength of DPIM PLA/CNC	408:443	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	6	40	theme	coupling	946:953	arg1	effect					955:960	this coupling effect	941:960	this coupling effect	941:960	At the same time, due to this coupling effect, more PLA shish-kebab structures were induced at the interface.					
35364194	3	41	theme	vicat	531:535	arg1	temperature					547:557	the vicat softening temperature	527:557	the vicat softening temperature of DPIM PLA/CNC	527:573	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	5	42	from	251 nm	866:871	arg1	length					854:859	PLA shish length	844:859	PLA shish length from 251 nm to 889 nm	844:881	CNC could increase PLA shish length from 251 nm to 889 nm under the action of shear field.					
35364194	4	43	theme	coupling	710:717	arg1	effect					719:724	the coupling effect	706:724	the coupling effect of CNC and strong shear flow field	706:759	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	3	44	theme	PLA/CNC	567:573	arg1	temperature					547:557	the vicat softening temperature	527:557	the vicat softening temperature of DPIM PLA/CNC	527:573	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	6	45	theme	same	923:926	arg1	time					928:931	the same time	919:931	the same time	919:931	At the same time, due to this coupling effect, more PLA shish-kebab structures were induced at the interface.					
35364194	2	46	theme	Cellulose	290:298	arg1	nanocrystal					300:310	Cellulose nanocrystal	290:310	Cellulose nanocrystal (CNC)	290:316	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	2	46	theme	Cellulose	290:298	arg1	CNC					313:315	CNC	313:315	CNC	313:315	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	5	47	theme	shear	903:907	arg1	field					909:913	shear field	903:913	shear field	903:913	CNC could increase PLA shish length from 251 nm to 889 nm under the action of shear field.					
35364194	3	48	theme	DPIM	432:435	arg1	PLA/CNC					437:443	DPIM PLA/CNC	432:443	DPIM PLA/CNC	432:443	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	1	49	theme	major	213:217	arg1	problems					219:226	two major problems	209:226	two major problems of polylactic acid (PLA)	209:251	Up to now, unbalanced mechanical properties and poor heat resistance have become two major problems of polylactic acid (PLA).					
35364194	0	50	theme	field	62:66	arg1	effect					13:18	The coupling effect	0:18	The coupling effect of cellulose nanocrystal and strong shear field	0:66	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	7	51	theme	strength	1187:1194	arg1	balance					1176:1182	the balance	1172:1182	the balance of strength and toughness of polymer materials	1172:1229	This special hierarchical structure composed of CNC and PLA Shish-Kebab is of great significance and can provide important guidance for achieving the balance of strength and toughness of polymer materials.					
35364194	5	52	theme	field	909:913	arg1	action					893:898	the action	889:898	the action of shear field	889:913	CNC could increase PLA shish length from 251 nm to 889 nm under the action of shear field.					
35364194	3	53	theme	tensile	412:418	arg1	strength					420:427	the tensile strength	408:427	the tensile strength of DPIM PLA/CNC	408:443	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	2	54	theme	strong	322:327	arg1	field					338:342	strong shearing field	322:342	strong shearing field	322:342	In this study, the coupling between Cellulose nanocrystal (CNC) and strong shearing field formed a unique hierarchical structure.					
35364194	0	55	theme	shear	56:60	arg1	field					62:66	strong shear field	49:66	strong shear field	49:66	The coupling effect of cellulose nanocrystal and strong shear field achieved the strength and toughness balance of Polylactide.					
35364194	3	56	theme	DPIM	562:565	arg1	PLA/CNC					567:573	DPIM PLA/CNC	562:573	DPIM PLA/CNC	562:573	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35364194	4	57	theme	PLA/CNC	629:635	arg1	composites					637:646	PLA/CNC composites	629:646	PLA/CNC composites	629:646	The microstructure of PLA/CNC composites was analyzed by SEM, SAXS and WAXD, and it was found that the coupling effect of CNC and strong shear flow field could significantly change the crystallization behavior of PLA.					
35364194	3	58	dep	155 °C	599:604	arg1	to					596:597	to	596:597	to	596:597	Compared with pure PLA, the tensile strength of DPIM PLA/CNC increased from 57.9 MPa to 79.6 MPa without sacrificing the toughness of PLA, and the vicat softening temperature of DPIM PLA/CNC increased from 60 °C to 155 °C.					
35176322	0	0	theme	alginate	91:98	arg1	hydrogels					114:122	photocrosslinked alginate nanocomposite hydrogels	74:122	photocrosslinked alginate nanocomposite hydrogels	74:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	6	1	theme	glassier	914:921	arg1	structure					923:931	a glassier structure	912:931	a glassier structure	912:931	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	1	2	theme	high	266:269	arg1	ratio					278:282	their high aspect ratio	260:282	their high aspect ratio	260:282	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	0	3	theme	photocrosslinked	74:89	arg1	hydrogels					114:122	photocrosslinked alginate nanocomposite hydrogels	74:122	photocrosslinked alginate nanocomposite hydrogels	74:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	6	4	theme	significant	944:954	arg1	reinforcement					956:968	a more significant reinforcement	937:968	a more significant reinforcement to the hydrogel	937:984	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	8	5	theme	degradation	1451:1461	arg1	energy					1433:1438	the activation energy	1418:1438	the activation energy of thermal degradation	1418:1461	Finally, both nanoparticle types produced an increase in the activation energy of thermal degradation.					
35176322	4	6	theme	macromonomers	716:728	arg1	nanoparticles					749:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	1	7	theme	aspect	271:276	arg1	ratio					278:282	their high aspect ratio	260:282	their high aspect ratio	260:282	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	0	8	theme	hydrogels	114:122	arg1	properties					60:69	properties	60:69	properties of photocrosslinked alginate nanocomposite hydrogels	60:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	0	9	from	Effect	0:5	arg1	properties					60:69	properties	60:69	properties of photocrosslinked alginate nanocomposite hydrogels	60:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	4	10	theme	nanofibers	778:787	arg1	photopolymerization					670:688	photopolymerization	670:688	photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers	670:798	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	0	11	theme	nanocomposite	100:112	arg1	hydrogels					114:122	photocrosslinked alginate nanocomposite hydrogels	74:122	photocrosslinked alginate nanocomposite hydrogels	74:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	3	12	theme	one-dimensional	517:531	arg1	nanoparticles					533:545	low aspect ratio one-dimensional nanoparticles	500:545	low aspect ratio one-dimensional nanoparticles	500:545	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	7	13	theme	due	1311:1313	arg1	structure					1301:1309	a more connected network structure	1276:1309	a more connected network structure due to the higher aspect ratio of the nanofibers	1276:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	2	14	theme	continuous	292:301	arg1	fibers					303:308	continuous fibers	292:308	continuous fibers	292:308	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	7	15	theme	nanofibers	1349:1358	arg1	ratio					1336:1340	the higher aspect ratio	1318:1340	the higher aspect ratio of the nanofibers	1318:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	16	theme	2.5-fold	1232:1239	arg1	decrease					1241:1248	2.5-fold decrease	1232:1248	2.5-fold decrease	1232:1248	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	16	theme	2.5-fold	1232:1239	arg1	capacity					1222:1229	a lower swelling capacity	1205:1229	a lower swelling capacity (2.5-fold decrease)	1205:1249	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	2	17	with	composites	314:323	arg1	fibers					336:341	short fibers	330:341	short fibers	330:341	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	1	18	theme	exciting	191:198	arg1	type					200:203	an exciting type	188:203	an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio	188:282	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	7	19	theme	swelling	1213:1220	arg1	decrease					1241:1248	2.5-fold decrease	1232:1248	2.5-fold decrease	1232:1248	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	19	theme	swelling	1213:1220	arg1	capacity					1222:1229	a lower swelling capacity	1205:1229	a lower swelling capacity (2.5-fold decrease)	1205:1249	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	5	20	theme	main	805:808	arg1	difference					810:819	The main difference	801:819	The main difference between the nanoparticles	801:845	The main difference between the nanoparticles lies in their length.					
35176322	2	21	theme	short	330:334	arg1	fibers					336:341	short fibers	330:341	short fibers	330:341	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	2	22	theme	cylindrical	383:393	arg1	surface					395:401	the cylindrical surface	379:401	the cylindrical surface of the fiber	379:414	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	2	23	theme	fiber	432:436	arg1	ends					438:441	the fiber ends	428:441	the fiber ends	428:441	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	3	24	theme	rheological	554:564	arg1	properties					588:597	the rheological, swelling and thermal properties	550:597	the rheological, swelling and thermal properties of nanocomposite hydrogels	550:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	6	25	theme	%	1030:1030	arg1	concentration					1007:1019	the concentration	1003:1019	the concentration of 0.5 wt%	1003:1030	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	0	26	theme	aspect	14:19	arg1	nanoparticles					43:55	low aspect ratio one-dimensional nanoparticles	10:55	low aspect ratio one-dimensional nanoparticles	10:55	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	4	27	theme	nanowires	764:772	arg1	photopolymerization					670:688	photopolymerization	670:688	photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers	670:798	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	3	28	from	influence	473:481	arg1	properties					588:597	the rheological, swelling and thermal properties	550:597	the rheological, swelling and thermal properties of nanocomposite hydrogels	550:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	3	29	theme	nanoparticles	533:545	arg1	length					490:495	the length	486:495	the length of low aspect ratio one-dimensional nanoparticles	486:545	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	1	30	theme	filler	208:213	arg1	type					200:203	an exciting type	188:203	an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio	188:282	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	0	31	theme	low	10:12	arg1	nanoparticles					43:55	low aspect ratio one-dimensional nanoparticles	10:55	low aspect ratio one-dimensional nanoparticles	10:55	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	3	32	theme	low	500:502	arg1	nanoparticles					533:545	low aspect ratio one-dimensional nanoparticles	500:545	low aspect ratio one-dimensional nanoparticles	500:545	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	1	33	theme	One-dimensional	125:139	arg1	wires					171:175	wires	171:175	wires	171:175	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	1	33	theme	One-dimensional	125:139	arg1	nanoparticles					141:153	One-dimensional nanoparticles	125:153	One-dimensional nanoparticles such as fibers	125:168	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	1	33	theme	One-dimensional	125:139	arg1	fibers					163:168	fibers	163:168	fibers	163:168	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	4	34	theme	alginate	707:714	arg1	macromonomers					716:728	alginate macromonomers	707:728	alginate macromonomers	707:728	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	0	35	theme	one-dimensional	27:41	arg1	nanoparticles					43:55	low aspect ratio one-dimensional nanoparticles	10:55	low aspect ratio one-dimensional nanoparticles	10:55	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	4	36	theme	aluminum	734:741	arg1	oxide					743:747	aluminum oxide	734:747	aluminum oxide	734:747	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	4	37	theme	nanocomposite	642:654	arg1	hydrogels					656:664	nanocomposite hydrogels	642:664	nanocomposite hydrogels	642:664	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	2	38	theme	fiber	410:414	arg1	surface					395:401	the cylindrical surface	379:401	the cylindrical surface of the fiber	379:414	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	0	39	theme	ratio	21:25	arg1	nanoparticles					43:55	low aspect ratio one-dimensional nanoparticles	10:55	low aspect ratio one-dimensional nanoparticles	10:55	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	6	40	theme	0.5 wt	1024:1029	arg1	%					1030:1030	0.5 wt%	1024:1030	0.5 wt%	1024:1030	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	3	41	theme	thermal	580:586	arg1	properties					588:597	the rheological, swelling and thermal properties	550:597	the rheological, swelling and thermal properties of nanocomposite hydrogels	550:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	1	42	theme	nanocomposite	229:241	arg1	hydrogels					243:251	nanocomposite hydrogels	229:251	nanocomposite hydrogels	229:251	One-dimensional nanoparticles such as fibers, wires, represent an exciting type of filler for obtaining nanocomposite hydrogels due to their high aspect ratio.					
35176322	7	43	theme	nanofibers	1170:1179	arg1	incorporation					1153:1165	the incorporation	1149:1165	the incorporation of nanofibers	1149:1179	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	0	44	link	photocrosslinked	74:89	arg1	hydrogels					114:122	photocrosslinked alginate nanocomposite hydrogels	74:122	photocrosslinked alginate nanocomposite hydrogels	74:122	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	4	45	theme	oxide	743:747	arg1	nanoparticles					749:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	0	46	theme	nanoparticles	43:55	arg1	Effect					0:5	Effect	0:5	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.	0:123	Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels.					
35176322	3	47	theme	swelling	567:574	arg1	properties					588:597	the rheological, swelling and thermal properties	550:597	the rheological, swelling and thermal properties of nanocomposite hydrogels	550:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	2	48	theme	stress	344:349	arg1	transfer					351:358	stress transfer	344:358	stress transfer	344:358	Unlike continuous fibers, in composites with short fibers, stress transfer occurs not only at the cylindrical surface of the fiber but also at the fiber ends.					
35176322	7	49	theme	connected	1283:1291	arg1	structure					1301:1309	a more connected network structure	1276:1309	a more connected network structure due to the higher aspect ratio of the nanofibers	1276:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	8	50	theme	thermal	1443:1449	arg1	degradation					1451:1461	thermal degradation	1443:1461	thermal degradation	1443:1461	Finally, both nanoparticle types produced an increase in the activation energy of thermal degradation.					
35176322	3	51	theme	nanocomposite	602:614	arg1	hydrogels					616:624	nanocomposite hydrogels	602:624	nanocomposite hydrogels	602:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	7	52	theme	network	1293:1299	arg1	structure					1301:1309	a more connected network structure	1276:1309	a more connected network structure due to the higher aspect ratio of the nanofibers	1276:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	8	53	theme	nanoparticle	1375:1386	arg1	types					1388:1392	both nanoparticle types	1370:1392	both nanoparticle types	1370:1392	Finally, both nanoparticle types produced an increase in the activation energy of thermal degradation.					
35176322	6	54	theme	Longer	869:874	arg1	nanoparticles					876:888	Longer nanoparticles	869:888	Longer nanoparticles (nanofibers)	869:901	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	6	54	theme	Longer	869:874	arg1	nanofibers					891:900	nanofibers	891:900	nanofibers	891:900	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	3	55	theme	hydrogels	616:624	arg1	properties					588:597	the rheological, swelling and thermal properties	550:597	the rheological, swelling and thermal properties of nanocomposite hydrogels	550:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	4	56	theme	nanoparticles	749:761	arg1	photopolymerization					670:688	photopolymerization	670:688	photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers	670:798	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	7	57	theme	higher	1322:1327	arg1	ratio					1336:1340	the higher aspect ratio	1318:1340	the higher aspect ratio of the nanofibers	1318:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	58	theme	aspect	1329:1334	arg1	ratio					1336:1340	the higher aspect ratio	1318:1340	the higher aspect ratio of the nanofibers	1318:1358	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	3	59	theme	length	490:495	arg1	influence					473:481	the influence	469:481	the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels	469:624	This work aimed to study the influence of the length of low aspect ratio one-dimensional nanoparticles on the rheological, swelling and thermal properties of nanocomposite hydrogels.					
35176322	7	60	with	hydrogels	1190:1198	arg1	decrease					1241:1248	2.5-fold decrease	1232:1248	2.5-fold decrease	1232:1248	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	60	with	hydrogels	1190:1198	arg1	capacity					1222:1229	a lower swelling capacity	1205:1229	a lower swelling capacity (2.5-fold decrease)	1205:1249	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	6	61	theme	complex	1036:1042	arg1	modulus					1044:1050	the complex modulus	1032:1050	the complex modulus	1032:1050	Longer nanoparticles (nanofibers) provided a glassier structure and a more significant reinforcement to the hydrogel, for example, at the concentration of 0.5 wt% the complex modulus increased approximately 2-fold and 8-fold for nanowires and nanofibers, respectively.					
35176322	8	62	from	increase	1406:1413	arg1	energy					1433:1438	the activation energy	1418:1438	the activation energy of thermal degradation	1418:1461	Finally, both nanoparticle types produced an increase in the activation energy of thermal degradation.					
35176322	7	63	theme	lower	1207:1211	arg1	decrease					1241:1248	2.5-fold decrease	1232:1248	2.5-fold decrease	1232:1248	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	7	63	theme	lower	1207:1211	arg1	capacity					1222:1229	a lower swelling capacity	1205:1229	a lower swelling capacity (2.5-fold decrease)	1205:1249	Similarly, the incorporation of nanofibers produced hydrogels with a lower swelling capacity (2.5-fold decrease), which was attributed to a more connected network structure due to the higher aspect ratio of the nanofibers.					
35176322	4	64	theme	methacrylated	693:705	arg1	nanoparticles					749:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	methacrylated alginate macromonomers and aluminum oxide nanoparticles	693:761	We synthesized nanocomposite hydrogels via photopolymerization of methacrylated alginate macromonomers and aluminum oxide nanoparticles, nanowires and nanofibers as fillers.					
35176322	8	65	theme	activation	1422:1431	arg1	energy					1433:1438	the activation energy	1418:1438	the activation energy of thermal degradation	1418:1461	Finally, both nanoparticle types produced an increase in the activation energy of thermal degradation.					
36353948	2	0	theme	selected	443:450	arg1	size					460:463	the selected serving size	439:463	the selected serving size	439:463	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	0	1	from	content	20:26	arg1	practice					49:56	clinical practice	40:56	clinical practice	40:56	Interpreting FODMAP content of foods in clinical practice.					
36353948	1	2	theme	discrepancies	127:139	arg1	issue					118:122	the important issue	104:122	the important issue of discrepancies in the FODMAP food-composition data published by various sources	104:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	2	3	from	differences	381:391	arg1	ratings					403:409	FODMAP ratings	396:409	FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content	396:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	1	4	from	issue	118:122	arg1	data					172:175	the FODMAP food-composition data	144:175	the FODMAP food-composition data published by various sources	144:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	2	5	theme	cut-off	472:478	arg1	criteria					480:487	cut-off criteria	472:487	cut-off criteria for high or low content	472:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	6	theme	FODMAP	355:360	arg1	content					362:368	FODMAP content	355:368	FODMAP content	355:368	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	7	dep	Martin	229:234	arg1	al					239:240	Martin et al	229:240	Martin et al	229:240	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	1	8	theme	FODMAP	148:153	arg1	data					172:175	the FODMAP food-composition data	144:175	the FODMAP food-composition data published by various sources	144:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	0	9	theme	FODMAP	13:18	arg1	content					20:26	FODMAP content	13:26	FODMAP content of foods in clinical practice	13:56	Interpreting FODMAP content of foods in clinical practice.					
36353948	2	10	from	differences	424:434	arg1	size					460:463	the selected serving size	439:463	the selected serving size	439:463	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	1	11	theme	food-composition	155:170	arg1	data					172:175	the FODMAP food-composition data	144:175	the FODMAP food-composition data published by various sources	144:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	2	12	theme	FODMAP	396:401	arg1	ratings					403:409	FODMAP ratings	396:409	FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content	396:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	13	theme	true	335:338	arg1	differences					340:350	true differences	335:350	true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content	335:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	14	theme	size	276:279	arg1	indication					254:263	no indication	251:263	no indication of serving size	251:279	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	15	theme	low	501:503	arg1	content					505:511	high or low content	493:511	high or low content	493:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	16	theme	serving	268:274	arg1	size					276:279	serving size	268:279	serving size	268:279	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	1	17	theme	various	190:196	arg1	sources					198:204	various sources	190:204	various sources	190:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	0	18	theme	foods	31:35	arg1	content					20:26	FODMAP content	13:26	FODMAP content of foods in clinical practice	13:56	Interpreting FODMAP content of foods in clinical practice.					
36353948	2	19	theme	high	493:496	arg1	content					505:511	high or low content	493:511	high or low content	493:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	20	dep	content	362:368	arg1	differences					381:391	differences	381:391	differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content	381:511	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	2	21	from	differences	340:350	arg1	content					362:368	FODMAP content	355:368	FODMAP content	355:368	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36353948	0	22	theme	clinical	40:47	arg1	practice					49:56	clinical practice	40:56	clinical practice	40:56	Interpreting FODMAP content of foods in clinical practice.					
36353948	1	23	theme	important	108:116	arg1	issue					118:122	the important issue	104:122	the important issue of discrepancies in the FODMAP food-composition data published by various sources	104:204	The article by San Mauro Martin et al raises the important issue of discrepancies in the FODMAP food-composition data published by various sources.					
36353948	2	24	theme	serving	452:458	arg1	size					460:463	the selected serving size	439:463	the selected serving size	439:463	The Table compiled by Martin et al provided no indication of serving size, so it is not clear whether the discrepancies reflect true differences in FODMAP content, or simply differences in FODMAP ratings arising from differences in the selected serving size and/or cut-off criteria for high or low content.					
36862579	7	0	dep	C18 	1013:1016	arg1	ω7c					1046:1048	ω7c	1046:1048	ω7c	1046:1048	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	0	dep	C18 	1013:1016	arg1	 0					1031:1032	 0	1031:1032	 0	1031:1032	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	0	dep	C18 	1013:1016	arg1	C16 					1026:1029	C16 	1026:1029	C16 	1026:1029	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	0	dep	C18 	1013:1016	arg1	C16 					1038:1041	C16 	1038:1041	C16 	1038:1041	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	6	1	theme	strain	822:827	arg1	genomes					811:817	the genomes	807:817	the genomes of strain GE09T and M. algicola Z1T	807:853	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	4	2	theme	nucleotide	539:548	arg1	identity					550:557	average nucleotide identity	531:557	average nucleotide identity	531:557	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	6	3	theme	carbohydrate-active	768:786	arg1	enzymes					788:794	The different carbohydrate-active enzymes	754:794	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T	754:853	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	8	4	theme	lipid	1061:1065	arg1	profile					1067:1073	The polar lipid profile	1051:1073	The polar lipid profile	1051:1073	The polar lipid profile showed phosphatidylglycerol and phosphatidylethanolamine.					
36862579	10	5	dep	name	1317:1320	arg1	sp					1356:1357	Marinagarivorans cellulosilyticus sp	1322:1357	the name Marinagarivorans cellulosilyticus sp	1313:1357	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	4	6	theme	average	531:537	arg1	identity					550:557	average nucleotide identity	531:557	average nucleotide identity	531:557	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	8	7	theme	polar	1055:1059	arg1	profile					1067:1073	The polar lipid profile	1051:1073	The polar lipid profile	1051:1073	The polar lipid profile showed phosphatidylglycerol and phosphatidylethanolamine.					
36862579	3	8	theme	97.4 	507:511	arg1	%					512:512	%	512:512	%	512:512	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	9	theme	%	512:512	arg1	relative					497:504	the closest relative	485:504	the closest relative (97.4 % similarity)	485:524	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	9	theme	%	512:512	arg1	similarity					514:523	97.4 % similarity	507:523	97.4 % similarity	507:523	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	10	10	theme	strain	1223:1228	arg1	GE09T					1230:1234	strain GE09T	1223:1234	strain GE09T	1223:1234	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	4	11	theme	identity	550:557	arg1	%					653:653	72.5 and 21.2 %	639:653	72.5 and 21.2 %	639:653	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	4	11	theme	identity	550:557	arg1	values					593:598	The average nucleotide identity and digital DNA-DNA hybridization values	527:598	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T	527:632	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	1	12	dep	Japan	113:117	arg1	off					96:98	off	96:98	off	96:98	nov., a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan.					
36862579	11	13	theme	type	1366:1369	arg1	35003T					1400:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	nov. (type strain GE09T=DSM 113420T=JCM 35003T).					
36862579	2	14	dep	Gram-stain-negative	234:252	arg1	aerobic					263:269	aerobic	263:269	aerobic	263:269	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	2	14	dep	Gram-stain-negative	234:252	arg1	motile					255:260	motile	255:260	motile	255:260	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	2	15	from	plate	206:210	arg1	sea					224:226	the deep sea	215:226	the deep sea	215:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	4	16	theme	digital	563:569	arg1	hybridization					579:591	digital DNA-DNA hybridization	563:591	digital DNA-DNA hybridization	563:591	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	10	17	from	species	1253:1259	arg1	Marinagarivorans					1274:1289	the genus Marinagarivorans	1264:1289	the genus Marinagarivorans	1264:1289	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	0	18	theme	cellulosilyticus	17:32	arg1	sp					34:35	cellulosilyticus sp	17:35	cellulosilyticus sp	17:35	Marinagarivorans cellulosilyticus sp.					
36862579	2	19	theme	strain	131:136	arg1	GE09T					138:142	strain GE09T	131:142	strain GE09T	131:142	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	7	20	theme	strain	995:1000	arg1	GE09T					1002:1006	strain GE09T	995:1006	strain GE09T	995:1006	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	21	theme	GE09T	1002:1006	arg1	C18 					1013:1016	C18 	1013:1016	C18 	1013:1016	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	21	theme	GE09T	1002:1006	arg1	acids					986:990	The major cellular fatty acids	961:990	The major cellular fatty acids of strain GE09T	961:1006	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	1	22	attach	isolated	69:76	arg2	bacterium					59:67	a cellulolytic bacterium	44:67	a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan	44:117	nov., a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan.					
36862579	1	22	attach	isolated	69:76	arg1	deep-sea					87:94	the deep-sea	83:94	the deep-sea	83:94	nov., a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan.					
36862579	6	23	theme	different	758:766	arg1	enzymes					788:794	The different carbohydrate-active enzymes	754:794	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T	754:853	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	9	24	theme	major	1137:1141	arg1	Q-8					1167:1169	Q-8	1167:1169	Q-8	1167:1169	The major respiratory quinone was Q-8.					
36862579	9	24	theme	major	1137:1141	arg1	quinone					1155:1161	The major respiratory quinone	1133:1161	The major respiratory quinone	1133:1161	The major respiratory quinone was Q-8.					
36862579	10	25	theme	new	1249:1251	arg1	species					1253:1259	a new species	1247:1259	a new species	1247:1259	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	6	26	theme	sources	910:916	arg1	terms					887:891	terms	887:891	terms of target energy sources	887:916	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	9	27	theme	respiratory	1143:1153	arg1	Q-8					1167:1169	Q-8	1167:1169	Q-8	1167:1169	The major respiratory quinone was Q-8.					
36862579	9	27	theme	respiratory	1143:1153	arg1	quinone					1155:1161	The major respiratory quinone	1133:1161	The major respiratory quinone	1133:1161	The major respiratory quinone was Q-8.					
36862579	6	28	theme	energy	903:908	arg1	sources					910:916	target energy sources	896:916	target energy sources	896:916	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	2	29	theme	immersed	175:182	arg1	plate					206:210	an artificially immersed nanofibrous cellulose plate	159:210	an artificially immersed nanofibrous cellulose plate in the deep sea	159:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	3	30	theme	agar	476:479	arg1	Z1T					450:452	Z1T	450:452	Z1T	450:452	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	30	theme	agar	476:479	arg1	degrader					464:471	a marine degrader	455:471	a marine degrader of agar	455:479	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	11	31	theme	strain	1371:1376	arg1	35003T					1400:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	nov. (type strain GE09T=DSM 113420T=JCM 35003T).					
36862579	11	32	theme	113420T=JCM	1388:1398	arg1	35003T					1400:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	nov. (type strain GE09T=DSM 113420T=JCM 35003T).					
36862579	2	33	from	GE09T	138:142	arg1	Cells					120:124	Cells	120:124	Cells	120:124	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	2	34	theme	only	317:320	arg1	nutrient					322:329	their only nutrient	311:329	their only nutrient	311:329	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	5	35	theme	Strain	670:675	arg1	GE09T					677:681	Strain GE09T	670:681	Strain GE09T	670:681	Strain GE09T degraded cellulose, xylan and pectin, but not starch, chitin and agar.					
36862579	6	36	theme	target	896:901	arg1	sources					910:916	target energy sources	896:916	target energy sources	896:916	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	11	37	theme	GE09T=DSM	1378:1386	arg1	35003T					1400:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	nov. (type strain GE09T=DSM 113420T=JCM 35003T).					
36862579	6	38	theme	isolation	937:945	arg1	environments					947:958	their isolation environments	931:958	their isolation environments	931:958	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	7	39	theme	major	965:969	arg1	C18 					1013:1016	C18 	1013:1016	C18 	1013:1016	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	39	theme	major	965:969	arg1	acids					986:990	The major cellular fatty acids	961:990	The major cellular fatty acids of strain GE09T	961:1006	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	3	40	theme	Strain	332:337	arg1	relative					497:504	the closest relative	485:504	the closest relative (97.4 % similarity)	485:524	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	40	theme	Strain	332:337	arg1	GE09T					339:343	Strain GE09T	332:343	Strain GE09T	332:343	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	41	theme	Cellvibrionaceae	373:388	arg1	members					362:368	members	362:368	members of Cellvibrionaceae	362:388	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	2	42	theme	deep	219:222	arg1	sea					224:226	the deep sea	215:226	the deep sea	215:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	7	43	theme	cellular	971:978	arg1	C18 					1013:1016	C18 	1013:1016	C18 	1013:1016	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	43	theme	cellular	971:978	arg1	acids					986:990	The major cellular fatty acids	961:990	The major cellular fatty acids of strain GE09T	961:1006	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	6	44	from	differences	872:882	arg1	terms					887:891	terms	887:891	terms of target energy sources	887:916	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	10	45	theme	cellulosilyticus	1339:1354	arg1	sp					1356:1357	Marinagarivorans cellulosilyticus sp	1322:1357	the name Marinagarivorans cellulosilyticus sp	1313:1357	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	2	46	attach	isolated	145:152	arg1	plate					206:210	an artificially immersed nanofibrous cellulose plate	159:210	an artificially immersed nanofibrous cellulose plate in the deep sea	159:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	2	46	attach	isolated	145:152	arg2	Cells					120:124	Cells	120:124	Cells	120:124	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	6	47	dep	genomes	811:817	arg1	Z1T					851:853	Z1T	851:853	Z1T	851:853	The different carbohydrate-active enzymes encoded in the genomes of strain GE09T and M. algicola Z1T highlights their differences in terms of target energy sources and reflects their isolation environments.					
36862579	7	48	theme	fatty	980:984	arg1	C18 					1013:1016	C18 	1013:1016	C18 	1013:1016	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	7	48	theme	fatty	980:984	arg1	acids					986:990	The major cellular fatty acids	961:990	The major cellular fatty acids of strain GE09T	961:1006	The major cellular fatty acids of strain GE09T were C18 : 1 ω7c, C16 : 0 and C16 : 1 ω7c.					
36862579	10	49	theme	taxonomic	1196:1204	arg1	characteristics					1206:1220	these distinct taxonomic characteristics	1181:1220	these distinct taxonomic characteristics	1181:1220	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	1	50	dep	bacterium	59:67	arg1	nov.					38:41	nov.	38:41	nov.	38:41	nov., a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan.					
36862579	4	51	theme	DNA-DNA	571:577	arg1	hybridization					579:591	digital DNA-DNA hybridization	563:591	digital DNA-DNA hybridization	563:591	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	2	52	theme	cellulose	196:204	arg1	plate					206:210	an artificially immersed nanofibrous cellulose plate	159:210	an artificially immersed nanofibrous cellulose plate in the deep sea	159:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	0	53	dep	sp	34:35	arg1	Marinagarivorans					0:15	Marinagarivorans	0:15	Marinagarivorans	0:15	Marinagarivorans cellulosilyticus sp.					
36862579	10	54	theme	genus	1268:1272	arg1	Marinagarivorans					1274:1289	the genus Marinagarivorans	1264:1289	the genus Marinagarivorans	1264:1289	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	3	55	theme	marine	457:462	arg1	Z1T					450:452	Z1T	450:452	Z1T	450:452	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	55	theme	marine	457:462	arg1	degrader					464:471	a marine degrader	455:471	a marine degrader of agar	455:479	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	2	56	theme	nanofibrous	184:194	arg1	plate					206:210	an artificially immersed nanofibrous cellulose plate	159:210	an artificially immersed nanofibrous cellulose plate in the deep sea	159:226	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	2	57	theme	Gram-stain-negative	234:252	arg1	cells					271:275	Gram-stain-negative, motile, aerobic cells	234:275	Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient	234:329	Cells from strain GE09T, isolated from an artificially immersed nanofibrous cellulose plate in the deep sea, were Gram-stain-negative, motile, aerobic cells that could grow with cellulose as their only nutrient.					
36862579	10	58	theme	Marinagarivorans	1322:1337	arg1	sp					1356:1357	Marinagarivorans cellulosilyticus sp	1322:1357	the name Marinagarivorans cellulosilyticus sp	1313:1357	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	1	59	theme	cellulolytic	46:57	arg1	bacterium					59:67	a cellulolytic bacterium	44:67	a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan	44:117	nov., a cellulolytic bacterium isolated from the deep-sea off Noma-misaki, Japan.					
36862579	11	60	dep	nov	1360:1362	arg1	35003T					1400:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	type strain GE09T=DSM 113420T=JCM 35003T	1366:1405	nov. (type strain GE09T=DSM 113420T=JCM 35003T).					
36862579	3	61	theme	closest	489:495	arg1	relative					497:504	the closest relative	485:504	the closest relative (97.4 % similarity)	485:524	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	61	theme	closest	489:495	arg1	GE09T					339:343	Strain GE09T	332:343	Strain GE09T	332:343	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	3	61	theme	closest	489:495	arg1	similarity					514:523	97.4 % similarity	507:523	97.4 % similarity	507:523	Strain GE09T was placed among members of Cellvibrionaceae, in the Gammaproteobacteria, with Marinagarivorans algicola Z1T, a marine degrader of agar, as the closest relative (97.4 % similarity).					
36862579	10	62	theme	distinct	1187:1194	arg1	characteristics					1206:1220	these distinct taxonomic characteristics	1181:1220	these distinct taxonomic characteristics	1181:1220	Based on these distinct taxonomic characteristics, strain GE09T represents a new species in the genus Marinagarivorans, for which we propose the name Marinagarivorans cellulosilyticus sp.					
36862579	4	63	theme	hybridization	579:591	arg1	%					653:653	72.5 and 21.2 %	639:653	72.5 and 21.2 %	639:653	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
36862579	4	63	theme	hybridization	579:591	arg1	values					593:598	The average nucleotide identity and digital DNA-DNA hybridization values	527:598	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T	527:632	The average nucleotide identity and digital DNA-DNA hybridization values between GE09T and M. algicola Z1T were 72.5 and 21.2 %, respectively.					
35617102	0	0	theme	Alginate/Polyacrylamide/Gallium	76:106	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	7	1	theme	sensor	1181:1186	arg1	device					1188:1193	the flexible sensor device	1168:1193	the flexible sensor device constructed from it	1168:1213	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	0	2	theme	Sodium	69:74	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	4	3	theme	excellent	553:561	arg1	properties					574:583	excellent mechanical properties	553:583	excellent mechanical properties	553:583	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	7	4	theme	S	1104:1104	arg1	m-1					1106:1108	1.9 S m-1	1100:1108	1.9 S m-1	1100:1108	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	4	theme	S	1104:1104	arg1	conductivity					1086:1097	the electrical conductivity	1071:1097	the electrical conductivity (1.9 S m-1) of the hydrogel	1071:1125	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	5	5	theme	flexible	636:643	arg1	sensor					645:650	a flexible sensor	634:650	a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate	634:737	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	6	6	theme	MJ	911:912	arg1	m-3					914:916	2.25 MJ m-3	906:916	2.25 MJ m-3	906:916	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	6	theme	MJ	911:912	arg1	high-toughness					890:903	a high-toughness	888:903	a high-toughness (2.25 MJ m-3)	888:917	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	7	7	theme	flexible	1172:1179	arg1	device					1188:1193	the flexible sensor device	1168:1193	the flexible sensor device constructed from it	1168:1213	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	0	8	theme	Composite	108:116	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	5	9	theme	sodium	723:728	arg1	alginate					730:737	sodium alginate	723:737	sodium alginate	723:737	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	10	theme	reactive	788:795	arg1	filler					809:814	a "reactive" conductive filler	785:814	a "reactive" conductive filler	785:814	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	10	theme	reactive	788:795	arg1	gallium					774:780	liquid metallic gallium	758:780	liquid metallic gallium	758:780	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	6	11	theme	elastic	838:844	arg1	modulus					846:852	a low elastic modulus	832:852	a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance	832:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	11	theme	elastic	838:844	arg1	kPa					858:860	30 kPa	855:860	30 kPa	855:860	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	2	12	theme	sensors	292:298	arg1	application					270:280	The application	266:280	The application of strain sensors prepared using them in human health monitoring and humanoid robotics	266:367	The application of strain sensors prepared using them in human health monitoring and humanoid robotics is developing rapidly.					
35617102	1	13	theme	classic	176:182	arg1	material					193:200	a classic flexible material	174:200	a classic flexible material	174:200	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	1	13	theme	classic	176:182	arg1	potential					224:232	great potential	218:232	great potential in wearable electronic devices	218:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	5	14	theme	"	796:796	arg1	filler					809:814	a "reactive" conductive filler	785:814	a "reactive" conductive filler	785:814	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	14	theme	"	796:796	arg1	gallium					774:780	liquid metallic gallium	758:780	liquid metallic gallium	758:780	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	8	15	theme	voice	1459:1463	arg1	motions					1375:1381	various human motions	1361:1381	various human motions	1361:1381	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	15	theme	voice	1459:1463	arg1	recognition					1465:1475	voice recognition	1459:1475	voice recognition	1459:1475	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	15	theme	voice	1459:1463	arg1	expression					1436:1445	tiny facial expression	1424:1445	tiny facial expression	1424:1445	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	15	theme	voice	1459:1463	arg1	bending					1412:1418	large-scale joint bending	1394:1418	large-scale joint bending	1394:1418	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	5	16	theme	strain-sensitive	667:682	arg1	hydrogel					694:701	a highly strain-sensitive skin-like hydrogel	658:701	a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate	658:737	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	6	17	theme	low	834:836	arg1	modulus					846:852	a low elastic modulus	832:852	a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance	832:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	17	theme	low	834:836	arg1	kPa					858:860	30 kPa	855:860	30 kPa	855:860	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	2	18	theme	strain	285:290	arg1	sensors					292:298	strain sensors	285:298	strain sensors	285:298	The application of strain sensors prepared using them in human health monitoring and humanoid robotics is developing rapidly.					
35617102	1	19	theme	flexible	184:191	arg1	material					193:200	a classic flexible material	174:200	a classic flexible material	174:200	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	1	19	theme	flexible	184:191	arg1	potential					224:232	great potential	218:232	great potential in wearable electronic devices	218:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	0	20	theme	Elastic	7:13	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	6	21	theme	tensile	944:950	arg1	deformation					952:962	a large tensile deformation	936:962	a large tensile deformation (1400%)	936:970	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	21	theme	tensile	944:950	arg1	%					969:969	1400%	965:969	1400%	965:969	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	5	22	theme	skin-like	684:692	arg1	hydrogel					694:701	a highly strain-sensitive skin-like hydrogel	658:701	a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate	658:737	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	23	theme	conductive	798:807	arg1	filler					809:814	a "reactive" conductive filler	785:814	a "reactive" conductive filler	785:814	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	23	theme	conductive	798:807	arg1	gallium					774:780	liquid metallic gallium	758:780	liquid metallic gallium	758:780	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	2	24	theme	health	329:334	arg1	monitoring					336:345	human health monitoring	323:345	human health monitoring	323:345	The application of strain sensors prepared using them in human health monitoring and humanoid robotics is developing rapidly.					
35617102	7	25	theme	high	1145:1148	arg1	transparency					1150:1161	high transparency	1145:1161	high transparency	1145:1161	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	4	26	theme	conductivity	605:616	arg1	integration					538:548	the integration	534:548	the integration of excellent mechanical properties and high electrical conductivity	534:616	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	9	27	theme	human-computer	1534:1547	arg1	communication					1549:1561	human-computer communication	1534:1561	human-computer communication	1534:1561	Furthermore, it might even be used for human-computer communication.					
35617102	0	28	with	Hydrogel	118:125	arg1	Toughness					132:140	Toughness	132:140	Toughness	132:140	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	2	29	theme	human	323:327	arg1	monitoring					336:345	human health monitoring	323:345	human health monitoring	323:345	The application of strain sensors prepared using them in human health monitoring and humanoid robotics is developing rapidly.					
35617102	8	30	theme	hydrogel	1331:1338	arg1	sensor					1340:1345	the hydrogel sensor	1327:1345	the hydrogel sensor	1327:1345	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	breathing					1448:1456	breathing	1448:1456	breathing	1448:1456	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	motions					1375:1381	various human motions	1361:1381	various human motions	1361:1381	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	recognition					1465:1475	voice recognition	1459:1475	voice recognition	1459:1475	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	expression					1436:1445	tiny facial expression	1424:1445	tiny facial expression	1424:1445	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	handwriting					1482:1492	handwriting	1482:1492	handwriting	1482:1492	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	result					1319:1324	a result	1317:1324	a result	1317:1324	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	31	theme	various	1361:1367	arg1	bending					1412:1418	large-scale joint bending	1394:1418	large-scale joint bending	1394:1418	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	0	32	theme	Sensitive	16:24	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	4	33	theme	electrical	594:603	arg1	conductivity					605:616	high electrical conductivity	589:616	high electrical conductivity	589:616	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	5	34	theme	liquid	758:763	arg1	filler					809:814	a "reactive" conductive filler	785:814	a "reactive" conductive filler	785:814	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	34	theme	liquid	758:763	arg1	gallium					774:780	liquid metallic gallium	758:780	liquid metallic gallium	758:780	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	35	theme	metallic	765:772	arg1	filler					809:814	a "reactive" conductive filler	785:814	a "reactive" conductive filler	785:814	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	35	theme	metallic	765:772	arg1	gallium					774:780	liquid metallic gallium	758:780	liquid metallic gallium	758:780	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	8	36	theme	human	1369:1373	arg1	breathing					1448:1456	breathing	1448:1456	breathing	1448:1456	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	motions					1375:1381	various human motions	1361:1381	various human motions	1361:1381	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	recognition					1465:1475	voice recognition	1459:1475	voice recognition	1459:1475	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	expression					1436:1445	tiny facial expression	1424:1445	tiny facial expression	1424:1445	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	handwriting					1482:1492	handwriting	1482:1492	handwriting	1482:1492	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	result					1319:1324	a result	1317:1324	a result	1317:1324	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	8	36	theme	human	1369:1373	arg1	bending					1412:1418	large-scale joint bending	1394:1418	large-scale joint bending	1394:1418	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	0	37	theme	Stretchable	27:37	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	5	38	with	hydrogel	694:701	arg1	acrylamide					708:717	acrylamide	708:717	acrylamide	708:717	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	5	38	with	hydrogel	694:701	arg1	alginate					730:737	sodium alginate	723:737	sodium alginate	723:737	In this study, a flexible sensor using a highly strain-sensitive skin-like hydrogel with acrylamide and sodium alginate was designed using liquid metallic gallium as a "reactive" conductive filler.					
35617102	0	39	theme	Strain	156:161	arg1	Sensor					163:168	a Flexible Strain Sensor	145:168	a Flexible Strain Sensor	145:168	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	3	40	theme	large-tensile-deformation	456:480	arg1	high-toughness					440:453	a high-toughness	438:453	a high-toughness	438:453	However, it is still a challenge to fabricate a high-toughness, large-tensile-deformation, strain-sensitive.					
35617102	1	41	theme	great	218:222	arg1	material					193:200	a classic flexible material	174:200	a classic flexible material	174:200	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	1	41	theme	great	218:222	arg1	potential					224:232	great potential	218:232	great potential in wearable electronic devices	218:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	4	42	theme	properties	574:583	arg1	integration					538:548	the integration	534:548	the integration of excellent mechanical properties and high electrical conductivity	534:616	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	0	43	theme	Flexible	147:154	arg1	Sensor					163:168	a Flexible Strain Sensor	145:168	a Flexible Strain Sensor	145:168	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	7	44	theme	hydrogel	1118:1125	arg1	m-1					1106:1108	1.9 S m-1	1100:1108	1.9 S m-1	1100:1108	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	44	theme	hydrogel	1118:1125	arg1	conductivity					1086:1097	the electrical conductivity	1071:1097	the electrical conductivity (1.9 S m-1) of the hydrogel	1071:1125	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	4	45	theme	mechanical	563:572	arg1	properties					574:583	excellent mechanical properties	553:583	excellent mechanical properties	553:583	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	1	46	from	potential	224:232	arg1	devices					257:263	wearable electronic devices	237:263	wearable electronic devices	237:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	8	47	theme	facial	1429:1434	arg1	expression					1436:1445	tiny facial expression	1424:1445	tiny facial expression	1424:1445	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	4	48	theme	high	589:592	arg1	conductivity					605:616	high electrical conductivity	589:616	high electrical conductivity	589:616	and human-skin-fit hydrogel with the integration of excellent mechanical properties and high electrical conductivity.					
35617102	8	49	theme	large-scale	1394:1404	arg1	bending					1412:1418	large-scale joint bending	1394:1418	large-scale joint bending	1394:1418	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	7	50	theme	electrical	1075:1084	arg1	m-1					1106:1108	1.9 S m-1	1100:1108	1.9 S m-1	1100:1108	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	50	theme	electrical	1075:1084	arg1	conductivity					1086:1097	the electrical conductivity	1071:1097	the electrical conductivity (1.9 S m-1) of the hydrogel	1071:1125	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	2	51	theme	humanoid	351:358	arg1	robotics					360:367	humanoid robotics	351:367	humanoid robotics	351:367	The application of strain sensors prepared using them in human health monitoring and humanoid robotics is developing rapidly.					
35617102	6	52	theme	large	938:942	arg1	deformation					952:962	a large tensile deformation	936:962	a large tensile deformation (1400%)	936:970	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	52	theme	large	938:942	arg1	%					969:969	1400%	965:969	1400%	965:969	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	53	theme	similar	863:869	arg1	modulus					846:852	a low elastic modulus	832:852	a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance	832:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	53	theme	similar	863:869	arg1	kPa					858:860	30 kPa	855:860	30 kPa	855:860	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	3	54	dep	large-tensile-deformation	456:480	arg1	strain-sensitive					483:498	strain-sensitive	483:498	strain-sensitive	483:498	However, it is still a challenge to fabricate a high-toughness, large-tensile-deformation, strain-sensitive.					
35617102	6	55	theme	excellent	993:1001	arg1	resistance					1011:1020	excellent fatigue resistance	993:1020	excellent fatigue resistance	993:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	56	theme	fatigue	1003:1009	arg1	resistance					1011:1020	excellent fatigue resistance	993:1020	excellent fatigue resistance	993:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	7	57	theme	gallium	1049:1055	arg1	addition					1037:1044	the addition	1033:1044	the addition of gallium	1033:1055	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	58	theme	=	1298:1298	arg1	pressure					1275:1282	pressure	1275:1282	pressure (gauge factor = 0.455 kPa-1)	1275:1311	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	58	theme	=	1298:1298	arg1	kPa-1					1306:1310	gauge factor = 0.455 kPa-1	1285:1310	gauge factor = 0.455 kPa-1	1285:1310	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	9	59	used	used	1525:1528	arg2	it					1508:1509	it	1508:1509	it	1508:1509	Furthermore, it might even be used for human-computer communication.					
35617102	1	60	theme	wearable	237:244	arg1	devices					257:263	wearable electronic devices	237:263	wearable electronic devices	237:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	0	61	theme	Conductive	58:67	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	8	62	theme	joint	1406:1410	arg1	bending					1412:1418	large-scale joint bending	1394:1418	large-scale joint bending	1394:1418	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	7	63	theme	gauge	1285:1289	arg1	pressure					1275:1282	pressure	1275:1282	pressure (gauge factor = 0.455 kPa-1)	1275:1311	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	63	theme	gauge	1285:1289	arg1	kPa-1					1306:1310	gauge factor = 0.455 kPa-1	1285:1310	gauge factor = 0.455 kPa-1	1285:1310	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	1	64	theme	electronic	246:255	arg1	devices					257:263	wearable electronic devices	237:263	wearable electronic devices	237:263	As a classic flexible material, hydrogels show great potential in wearable electronic devices.					
35617102	0	65	theme	Skin-Inspired	44:56	arg1	Hydrogel					118:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel	0:125	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.	0:169	Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor.					
35617102	8	66	theme	tiny	1424:1427	arg1	expression					1436:1445	tiny facial expression	1424:1445	tiny facial expression	1424:1445	As a result, the hydrogel sensor could monitor various human motions, including large-scale joint bending and tiny facial expression, breathing, voice recognition, and handwriting.					
35617102	7	67	theme	factor	1291:1296	arg1	pressure					1275:1282	pressure	1275:1282	pressure (gauge factor = 0.455 kPa-1)	1275:1311	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	67	theme	factor	1291:1296	arg1	kPa-1					1306:1310	gauge factor = 0.455 kPa-1	1285:1310	gauge factor = 0.455 kPa-1	1285:1310	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	7	68	theme	high	1222:1225	arg1	sensitivity					1227:1237	high sensitivity	1222:1237	high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1)	1222:1311	Moreover, the addition of gallium might enhance the electrical conductivity (1.9 S m-1) of the hydrogel while maintaining high transparency, and the flexible sensor device constructed from it showed high sensitivity to strain (gauge factor = 4.08) and pressure (gauge factor = 0.455 kPa-1).					
35617102	6	69	contain	had	828:830	arg2	kPa					858:860	30 kPa	855:860	30 kPa	855:860	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	69	contain	had	828:830	arg1	sensor					821:826	The sensor	817:826	The sensor	817:826	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35617102	6	69	contain	had	828:830	arg2	modulus					846:852	a low elastic modulus	832:852	a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance	832:1020	The sensor had a low elastic modulus (30 kPa) similar to that of skin, a high-toughness (2.25 MJ m-3), self-stiffness, a large tensile deformation (1400%), recoverability, and excellent fatigue resistance.					
35654194	11	0	contain	has	1722:1724	arg1	Gel/CS/PPy					1711:1720	the synthesized Gel/CS/PPy	1695:1720	the synthesized Gel/CS/PPy	1695:1720	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	11	0	contain	has	1722:1724	arg2	potential					1732:1740	great potential	1726:1740	great potential	1726:1740	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	9	1	theme	optimal	1381:1387	arg1	condition					1399:1407	The optimal operating condition	1377:1407	The optimal operating condition for Cr	1377:1414	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	1	theme	optimal	1381:1387	arg1	dose					1449:1452	pH = 3; 2 g/L dose	1435:1452	pH = 3; 2 g/L dose of Gel/CS/PPy	1435:1466	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	1	2	theme	certain	220:226	arg1	conditions					228:237	certain conditions	220:237	certain conditions	220:237	Cr (VI) exists in anion form and can be reduced to positive charged Cr (III) under certain conditions.					
35654194	11	3	theme	concentration	1778:1790	arg1	Cr					1792:1793	low concentration Cr (VI) treatment in water	1774:1817	low concentration Cr (VI) treatment in water	1774:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	10	4	theme	purity	1615:1620	arg1	chromium					1622:1629	high purity chromium	1610:1629	high purity chromium	1610:1629	Since Gel/CS/PPy is composed of organic components, high purity chromium can be recovered by simple calcination method later.					
35654194	2	5	theme	charged	253:259	arg1	Cr					261:262	positive charged Cr (III)	244:268	positive charged Cr (III)	244:268	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	6	6	theme	Cr	1022:1023	arg1	conversion					1008:1017	The conversion	1004:1017	The conversion of Cr (VI) and Cr (III)	1004:1041	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	6	6	theme	Cr	1022:1023	arg1	effect					1061:1066	its promoting effect	1047:1066	its promoting effect on readsorption	1047:1082	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	6	7	dep	Cr	1022:1023	arg1	VI					1026:1027	VI	1026:1027	VI	1026:1027	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	11	8	dep	Cr	1792:1793	arg1	treatment					1800:1808	treatment	1800:1808	low concentration Cr (VI) treatment in water	1774:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	11	8	dep	Cr	1792:1793	arg1	VI					1796:1797	VI	1796:1797	VI	1796:1797	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	5	9	theme	Fourier	822:828	arg1	spectroscopy					849:860	Fourier transform-infrared spectroscopy	822:860	Fourier transform-infrared spectroscopy (FT-IR)	822:868	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	9	theme	Fourier	822:828	arg1	FT-IR					863:867	FT-IR	863:867	FT-IR	863:867	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	7	10	dep	Cr	1174:1175	arg1	VI					1178:1179	VI	1178:1179	VI	1178:1179	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	11	11	theme	great	1726:1730	arg1	potential					1732:1740	great potential	1726:1740	great potential	1726:1740	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	7	12	theme	excellent	1186:1194	arg1	ability					1211:1217	excellent photocatalytic ability	1186:1217	excellent photocatalytic ability	1186:1217	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	5	13	theme	zeta	929:932	arg1	potential					934:942	zeta potential	929:942	zeta potential	929:942	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	1	14	theme	charged	197:203	arg1	Cr					205:206	positive charged Cr (III)	188:212	positive charged Cr (III)	188:212	Cr (VI) exists in anion form and can be reduced to positive charged Cr (III) under certain conditions.					
35654194	0	15	from	transformation	53:66	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	10	16	theme	simple	1651:1656	arg1	method					1670:1675	simple calcination method	1651:1675	simple calcination method	1651:1675	Since Gel/CS/PPy is composed of organic components, high purity chromium can be recovered by simple calcination method later.					
35654194	5	17	theme	electron	795:802	arg1	SEM					816:818	SEM	816:818	SEM	816:818	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	17	theme	electron	795:802	arg1	microscopy					804:813	scanning electron microscopy	786:813	scanning electron microscopy (SEM)	786:819	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	11	18	theme	practical	1749:1757	arg1	application					1759:1769	the practical application	1745:1769	the practical application of low concentration Cr (VI) treatment in water	1745:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	5	19	theme	Universal	914:922	arg1	analyzer					904:911	texture analyzer	896:911	texture analyzer (Universal TA)	896:926	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	19	theme	Universal	914:922	arg1	TA					924:925	Universal TA	914:925	Universal TA	914:925	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	9	20	theme	Gel/CS/PPy	1457:1466	arg1	condition					1399:1407	The optimal operating condition	1377:1407	The optimal operating condition for Cr	1377:1414	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	20	theme	Gel/CS/PPy	1457:1466	arg1	dose					1449:1452	pH = 3; 2 g/L dose	1435:1452	pH = 3; 2 g/L dose of Gel/CS/PPy	1435:1466	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	20	theme	Gel/CS/PPy	1457:1466	arg1	mg/g					1524:1527	about 106.8 mg/g	1512:1527	about 106.8 mg/g	1512:1527	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	20	theme	Gel/CS/PPy	1457:1466	arg1	capacity					1488:1495	the adsorption capacity	1473:1495	the adsorption capacity of Cr	1473:1501	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	8	21	used	used	1292:1295	arg2	Gel/CS/PPy					1266:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	0	22	theme	metal-free	71:80	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	8	23	dep	Cr	1307:1308	arg1	VI					1311:1312	VI	1311:1312	VI	1311:1312	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	1	24	theme	anion	155:159	arg1	form					161:164	anion form	155:164	anion form	155:164	Cr (VI) exists in anion form and can be reduced to positive charged Cr (III) under certain conditions.					
35654194	4	25	theme	cyclic	586:591	arg1	process					604:610	a cyclic enrichment process	584:610	a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr	584:674	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	0	26	theme	reductive	97:105	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	9	27	dep	mg/g	1524:1527	arg1	VI					1504:1505	VI	1504:1505	VI	1504:1505	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	28	theme	adsorption	1477:1486	arg1	mg/g					1524:1527	about 106.8 mg/g	1512:1527	about 106.8 mg/g	1512:1527	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	28	theme	adsorption	1477:1486	arg1	capacity					1488:1495	the adsorption capacity	1473:1495	the adsorption capacity of Cr	1473:1501	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	0	29	theme	composite	117:125	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	5	30	theme	infrared	973:980	arg1	UV-vis-NIR					991:1000	UV-vis-NIR	991:1000	UV-vis-NIR	991:1000	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	30	theme	infrared	973:980	arg1	spectra					982:988	ultraviolet-visible-near infrared spectra	948:988	ultraviolet-visible-near infrared spectra (UV-vis-NIR)	948:1001	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	2	31	used	used	285:288	arg2	Cr					261:262	positive charged Cr (III)	244:268	positive charged Cr (III)	244:268	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	0	32	theme	Cyclic	0:5	arg1	enrichment					7:16	Cyclic enrichment	0:16	Cyclic enrichment of chromium	0:28	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	7	33	theme	good	1145:1148	arg1	capacity					1161:1168	good adsorption capacity	1145:1168	good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III)	1145:1247	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	4	34	theme	enrichment	593:602	arg1	process					604:610	a cyclic enrichment process	584:610	a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr	584:674	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	3	35	dep	prepared	428:435	arg1	VI					420:421	VI	420:421	VI	420:421	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	2	36	theme	chromium	346:353	arg1	accumulation					330:341	cyclic accumulation	323:341	cyclic accumulation of chromium	323:353	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	3	37	theme	ion	374:376	arg1	material					389:396	an ion imprinting material	371:396	an ion imprinting material for adsorption of Cr	371:417	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	4	38	theme	Gel/CS/PPy	700:709	arg1	hydrogel					711:718	Gel/CS/PPy hydrogel	700:718	Gel/CS/PPy hydrogel	700:718	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	3	39	theme	Cr	416:417	arg1	adsorption					402:411	adsorption	402:411	adsorption of Cr	402:417	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	0	40	theme	valence	39:45	arg1	transformation					53:66	valence state transformation	39:66	valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel	39:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	5	41	theme	texture	896:902	arg1	analyzer					904:911	texture analyzer	896:911	texture analyzer (Universal TA)	896:926	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	41	theme	texture	896:902	arg1	TA					924:925	Universal TA	914:925	Universal TA	914:925	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	2	42	dep	achieve	315:321	arg1	VI					308:309	VI	308:309	VI	308:309	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	8	43	theme	adsorption	1331:1340	arg1	efficiency					1342:1351	good adsorption efficiency	1326:1351	good adsorption efficiency	1326:1351	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	9	44	theme	operating	1389:1397	arg1	condition					1399:1407	The optimal operating condition	1377:1407	The optimal operating condition for Cr	1377:1414	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	44	theme	operating	1389:1397	arg1	dose					1449:1452	pH = 3; 2 g/L dose	1435:1452	pH = 3; 2 g/L dose of Gel/CS/PPy	1435:1466	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	11	45	theme	Cr	1792:1793	arg1	application					1759:1769	the practical application	1745:1769	the practical application of low concentration Cr (VI) treatment in water	1745:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	10	46	theme	high	1610:1613	arg1	chromium					1622:1629	high purity chromium	1610:1629	high purity chromium	1610:1629	Since Gel/CS/PPy is composed of organic components, high purity chromium can be recovered by simple calcination method later.					
35654194	2	47	theme	positive	244:251	arg1	Cr					261:262	positive charged Cr (III)	244:268	positive charged Cr (III)	244:268	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	4	48	theme	Cr	563:564	arg1	conversion					549:558	the conversion	545:558	the conversion of Cr	545:564	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	7	49	dep	Cr	1229:1230	arg1	VI					1233:1234	VI	1233:1234	VI	1233:1234	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	7	49	dep	Cr	1229:1230	arg1	Cr					1240:1241	Cr (III)	1240:1247	Cr (VI) to Cr (III)	1229:1247	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	7	49	dep	Cr	1229:1230	arg1	to					1237:1238	to	1237:1238	to	1237:1238	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	11	50	from	water	1813:1817	arg1	application					1759:1769	the practical application	1745:1769	the practical application of low concentration Cr (VI) treatment in water	1745:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	9	51	dep	dose	1449:1452	arg1	VI					1417:1418	VI	1417:1418	VI	1417:1418	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	3	52	theme	Gel/CS	492:497	arg1	network					509:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	1	53	theme	positive	188:195	arg1	Cr					205:206	positive charged Cr (III)	188:212	positive charged Cr (III)	188:212	Cr (VI) exists in anion form and can be reduced to positive charged Cr (III) under certain conditions.					
35654194	9	54	theme	=	1438:1438	arg1	condition					1399:1407	The optimal operating condition	1377:1407	The optimal operating condition for Cr	1377:1414	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	54	theme	=	1438:1438	arg1	dose					1449:1452	pH = 3; 2 g/L dose	1435:1452	pH = 3; 2 g/L dose of Gel/CS/PPy	1435:1466	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	6	55	theme	promoting	1051:1059	arg1	effect					1061:1066	its promoting effect	1047:1066	its promoting effect on readsorption	1047:1082	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	10	56	theme	calcination	1658:1668	arg1	method					1670:1675	simple calcination method	1651:1675	simple calcination method	1651:1675	Since Gel/CS/PPy is composed of organic components, high purity chromium can be recovered by simple calcination method later.					
35654194	3	57	theme	gelatin/chitosan	474:489	arg1	network					509:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	5	58	theme	scanning	786:793	arg1	SEM					816:818	SEM	816:818	SEM	816:818	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	58	theme	scanning	786:793	arg1	microscopy					804:813	scanning electron microscopy	786:813	scanning electron microscopy (SEM)	786:819	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	11	59	theme	low	1774:1776	arg1	Cr					1792:1793	low concentration Cr (VI) treatment in water	1774:1817	low concentration Cr (VI) treatment in water	1774:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	8	60	theme	Cr	1250:1251	arg1	Gel/CS/PPy					1266:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	7	61	contain	has	1141:1143	arg2	capacity					1161:1168	good adsorption capacity	1145:1168	good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III)	1145:1247	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	7	61	contain	has	1141:1143	arg1	Gel/CS/PPy					1130:1139	Gel/CS/PPy	1130:1139	Gel/CS/PPy	1130:1139	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	9	62	theme	g/L	1445:1447	arg1	condition					1399:1407	The optimal operating condition	1377:1407	The optimal operating condition for Cr	1377:1414	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	62	theme	g/L	1445:1447	arg1	dose					1449:1452	pH = 3; 2 g/L dose	1435:1452	pH = 3; 2 g/L dose of Gel/CS/PPy	1435:1466	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	6	63	from	effect	1061:1066	arg1	readsorption					1071:1082	readsorption	1071:1082	readsorption	1071:1082	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	11	64	from	application	1759:1769	arg1	water					1813:1817	water	1813:1817	water	1813:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	3	65	theme	hydrogel	500:507	arg1	network					509:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	5	66	theme	Gel/CS/PPy	758:767	arg1	structure					741:749	structure	741:749	structure	741:749	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	66	theme	Gel/CS/PPy	758:767	arg1	composition					725:735	The composition	721:735	The composition	721:735	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	8	67	theme	-loaded	1258:1264	arg1	Gel/CS/PPy					1266:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy	1250:1275	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	6	68	theme	Cr	1034:1035	arg1	conversion					1008:1017	The conversion	1004:1017	The conversion of Cr (VI) and Cr (III)	1004:1041	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	6	68	theme	Cr	1034:1035	arg1	effect					1061:1066	its promoting effect	1047:1066	its promoting effect on readsorption	1047:1082	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	0	69	theme	photocatalytic	82:95	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	3	70	from	polypyrrole	451:461	arg1	network					509:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	a gelatin/chitosan (Gel/CS) hydrogel network	472:515	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	0	71	theme	imprinted	107:115	arg1	hydrogel					127:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	metal-free photocatalytic reductive imprinted composite hydrogel	71:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	5	72	theme	transform-infrared	830:847	arg1	spectroscopy					849:860	Fourier transform-infrared spectroscopy	822:860	Fourier transform-infrared spectroscopy (FT-IR)	822:868	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	72	theme	transform-infrared	830:847	arg1	FT-IR					863:867	FT-IR	863:867	FT-IR	863:867	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	11	73	theme	synthesized	1699:1709	arg1	Gel/CS/PPy					1711:1720	the synthesized Gel/CS/PPy	1695:1720	the synthesized Gel/CS/PPy	1695:1720	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
35654194	5	74	theme	ultraviolet-visible-near	948:971	arg1	UV-vis-NIR					991:1000	UV-vis-NIR	991:1000	UV-vis-NIR	991:1000	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	5	74	theme	ultraviolet-visible-near	948:971	arg1	spectra					982:988	ultraviolet-visible-near infrared spectra	948:988	ultraviolet-visible-near infrared spectra (UV-vis-NIR)	948:1001	The composition and structure of the Gel/CS/PPy were analyzed by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), thermogravimetric (TGA), texture analyzer (Universal TA), zeta potential and ultraviolet-visible-near infrared spectra (UV-vis-NIR).					
35654194	7	75	theme	adsorption	1150:1159	arg1	capacity					1161:1168	good adsorption capacity	1145:1168	good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III)	1145:1247	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	2	76	theme	cyclic	323:328	arg1	accumulation					330:341	cyclic accumulation	323:341	cyclic accumulation of chromium	323:353	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	9	77	theme	Cr	1500:1501	arg1	mg/g					1524:1527	about 106.8 mg/g	1512:1527	about 106.8 mg/g	1512:1527	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	9	77	theme	Cr	1500:1501	arg1	capacity					1488:1495	the adsorption capacity	1473:1495	the adsorption capacity of Cr	1473:1501	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	6	78	from	conversion	1008:1017	arg1	readsorption					1071:1082	readsorption	1071:1082	readsorption	1071:1082	The conversion of Cr (VI) and Cr (III) and its promoting effect on readsorption were verified by XPS.					
35654194	0	79	theme	chromium	21:28	arg1	enrichment					7:16	Cyclic enrichment	0:16	Cyclic enrichment of chromium	0:28	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	1	80	dep	exists	145:150	arg1	VI					141:142	VI	141:142	VI	141:142	Cr (VI) exists in anion form and can be reduced to positive charged Cr (III) under certain conditions.					
35654194	4	81	dep	established	685:695	arg1	Based					536:540	Based	536:540	Based on the conversion of Cr	536:564	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	4	81	dep	established	685:695	arg1	VI					677:678	VI	677:678	VI	677:678	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	4	81	dep	established	685:695	arg1	VI					567:568	VI	567:568	VI	567:568	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	3	82	theme	imprinting	378:387	arg1	material					389:396	an ion imprinting material	371:396	an ion imprinting material for adsorption of Cr	371:417	In this paper, an ion imprinting material for adsorption of Cr (VI) was prepared by dispersing polypyrrole (PPy) in a gelatin/chitosan (Gel/CS) hydrogel network, named Gel/CS/PPy.					
35654194	0	83	theme	state	47:51	arg1	transformation					53:66	valence state transformation	39:66	valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel	39:134	Cyclic enrichment of chromium based on valence state transformation in metal-free photocatalytic reductive imprinted composite hydrogel.					
35654194	8	84	theme	good	1326:1329	arg1	efficiency					1342:1351	good adsorption efficiency	1326:1351	good adsorption efficiency	1326:1351	Cr (III)-loaded Gel/CS/PPy can be further used to adsorb Cr (VI) and showed good adsorption efficiency even after four cycles.					
35654194	2	85	theme	absorbing	294:302	arg1	Cr					304:305	absorbing Cr	294:305	absorbing Cr	294:305	Can positive charged Cr (III) be continually used for absorbing Cr (VI) to achieve cyclic accumulation of chromium?					
35654194	7	86	theme	photocatalytic	1196:1209	arg1	ability					1211:1217	excellent photocatalytic ability	1186:1217	excellent photocatalytic ability	1186:1217	The results showed that Gel/CS/PPy has good adsorption capacity for Cr (VI) and excellent photocatalytic ability to reduce Cr (VI) to Cr (III).					
35654194	4	87	theme	Cr	673:674	arg1	adsorption-photoreduction-fixation-readsorption					622:668	adsorption-photoreduction-fixation-readsorption	622:668	adsorption-photoreduction-fixation-readsorption of Cr	622:674	Based on the conversion of Cr (VI) to Cr (III), a cyclic enrichment process including adsorption-photoreduction-fixation-readsorption of Cr (VI) was established in Gel/CS/PPy hydrogel.					
35654194	9	88	theme	adsorption	1539:1548	arg1	cycles					1550:1555	six adsorption cycles	1535:1555	six adsorption cycles	1535:1555	The optimal operating condition for Cr (VI) adsorption is pH = 3; 2 g/L dose of Gel/CS/PPy; and the adsorption capacity of Cr (VI) was about 106.8 mg/g after six adsorption cycles.					
35654194	10	89	theme	organic	1590:1596	arg1	components					1598:1607	organic components	1590:1607	organic components	1590:1607	Since Gel/CS/PPy is composed of organic components, high purity chromium can be recovered by simple calcination method later.					
35654194	11	90	from	Cr	1792:1793	arg1	water					1813:1817	water	1813:1817	water	1813:1817	Therefore, the synthesized Gel/CS/PPy has great potential in the practical application of low concentration Cr (VI) treatment in water.					
37217054	2	0	theme	disposed	545:552	arg1	conditions					554:563	disposed conditions	545:563	disposed conditions	545:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	8	1	theme	extract	1635:1641	arg1	introduction					1593:1604	the minute introduction	1582:1604	the minute introduction of plant-derived anthocyanin extract into it	1582:1649	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	2	2	theme	underutilized	405:417	arg1	sources					419:425	underutilized sources	405:425	underutilized sources	405:425	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	9	3	from	changes	1710:1716	arg1	color					1721:1725	color	1721:1725	color	1721:1725	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	0	4	theme	yam	83:85	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	4	theme	yam	83:85	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	1	5	from	resources	359:367	arg1	production					333:342	biodegradable bioplastic production	308:342	biodegradable bioplastic production from renewable resources	308:367	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	6	6	theme	starch	1186:1191	arg1	bioplastics					1193:1203	starch bioplastics	1186:1203	starch bioplastics	1186:1203	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	1	7	theme	current	161:167	arg1	scenario					169:176	The current scenario	157:176	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources	157:277	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	9	8	from	change	1743:1748	arg1	value					1760:1764	the pH value	1753:1764	the pH value	1753:1764	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	9	9	theme	produced	1656:1663	arg1	film					1689:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	8	10	theme	anthocyanin	1623:1633	arg1	extract					1635:1641	plant-derived anthocyanin extract	1609:1641	plant-derived anthocyanin extract	1609:1641	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	3	11	theme	undesirable	613:623	arg1	qualities					625:633	some undesirable qualities	608:633	some undesirable qualities	608:633	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	5	12	theme	citric	1058:1063	arg1	modifier					1091:1098	modifier	1091:1098	modifier	1091:1098	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	5	12	theme	citric	1058:1063	arg1	CA					1071:1072	CA	1071:1072	CA	1071:1072	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	5	12	theme	citric	1058:1063	arg1	acid					1065:1068	citric acid	1058:1068	citric acid (CA)	1058:1073	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	6	13	theme	maximum	1255:1261	arg1	strength					1271:1278	maximum tensile strength	1255:1278	maximum tensile strength of 24.60 MPa	1255:1291	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	6	13	theme	maximum	1255:1261	arg1	result					1340:1345	the best possible experimental result	1309:1345	the best possible experimental result	1309:1345	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	9	14	theme	smart	1806:1810	arg1	material					1827:1834	a smart food packaging material	1804:1834	a smart food packaging material	1804:1834	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	4	15	theme	eco-friendly	827:838	arg1	process					861:867	an eco-friendly and energy-efficient process	824:867	an eco-friendly and energy-efficient process which was further utilized for bioplastic production	824:920	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	3	16	theme	Pristine	566:573	arg1	production					586:595	Pristine bioplastic production	566:595	Pristine bioplastic production	566:595	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	7	17	theme	biodegradability	1352:1367	arg1	feature					1369:1375	The biodegradability feature	1348:1375	The biodegradability feature	1348:1375	The biodegradability feature was further highlighted through soil burial test.					
37217054	8	18	link	plant-derived	1609:1621	arg1	extract					1635:1641	plant-derived anthocyanin extract	1609:1641	plant-derived anthocyanin extract	1609:1641	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	9	19	theme	distinct	1701:1708	arg1	changes					1710:1716	distinct changes	1701:1716	distinct changes in color	1701:1725	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	2	20	theme	viable	432:437	arg1	option					439:444	a viable option	430:444	a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions	430:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	2	20	theme	viable	432:437	arg1	production					389:398	Starch bioplastics production	370:398	Starch bioplastics production from underutilized sources	370:425	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	6	21	theme	different	1160:1168	arg1	compositions					1170:1181	The different compositions	1156:1181	The different compositions of starch bioplastics	1156:1203	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	2	22	dep	non-toxic	479:487	arg1	benign					506:511	benign	506:511	benign	506:511	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	2	22	dep	non-toxic	479:487	arg1	biodegradable					525:537	biodegradable	525:537	biodegradable	525:537	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	4	23	theme	energy-efficient	844:859	arg1	process					861:867	an eco-friendly and energy-efficient process	824:867	an eco-friendly and energy-efficient process which was further utilized for bioplastic production	824:920	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	9	24	theme	pH-sensitive	1665:1676	arg1	film					1689:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	7	25	theme	soil	1409:1412	arg1	test					1421:1424	soil burial test	1409:1424	soil burial test	1409:1424	The biodegradability feature was further highlighted through soil burial test.					
37217054	4	26	theme	yams	811:814	arg1	yams					811:814	yams	811:814	yams	811:814	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	4	26	theme	yams	811:814	arg1	variety					800:806	a local variety	792:806	a local variety of yams	792:814	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	1	27	theme	environmental	181:193	arg1	pollution					195:203	environmental pollution	181:203	environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources	181:277	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	8	28	theme	plant-derived	1609:1621	arg1	extract					1635:1641	plant-derived anthocyanin extract	1609:1641	plant-derived anthocyanin extract	1609:1641	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	3	29	theme	further	654:660	arg1	modification					662:673	further modification in order to elevate its potential applicability in real-world scenarios	654:745	further modification in order to elevate its potential applicability in real-world scenarios	654:745	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	1	30	theme	pollution	195:203	arg1	scenario					169:176	The current scenario	157:176	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources	157:277	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	0	31	theme	biodegradable	22:34	arg1	bioplastic					36:45	A mechanically robust biodegradable bioplastic	0:45	A mechanically robust biodegradable bioplastic of citric acid	0:60	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	32	theme	spoilage	121:128	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	32	theme	spoilage	121:128	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	2	33	from	sources	419:425	arg1	option					439:444	a viable option	430:444	a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions	430:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	2	33	from	sources	419:425	arg1	production					389:398	Starch bioplastics production	370:398	Starch bioplastics production from underutilized sources	370:425	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	8	34	theme	produced	1497:1504	arg1	bioplastic					1506:1515	the produced bioplastic	1493:1515	the produced bioplastic	1493:1515	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	4	35	used	utilized	887:894	arg2	process					861:867	an eco-friendly and energy-efficient process	824:867	an eco-friendly and energy-efficient process which was further utilized for bioplastic production	824:920	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	9	36	theme	pH	1757:1758	arg1	value					1760:1764	the pH value	1753:1764	the pH value	1753:1764	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	0	37	theme	robust	15:20	arg1	bioplastic					36:45	A mechanically robust biodegradable bioplastic	0:45	A mechanically robust biodegradable bioplastic of citric acid	0:60	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	1	38	theme	biodegradable	308:320	arg1	production					333:342	biodegradable bioplastic production	308:342	biodegradable bioplastic production from renewable resources	308:367	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	0	39	theme	fish	116:119	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	39	theme	fish	116:119	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	3	40	theme	bioplastic	575:584	arg1	production					586:595	Pristine bioplastic production	566:595	Pristine bioplastic production	566:595	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	9	41	theme	bioplastic	1678:1687	arg1	film					1689:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	5	42	theme	produced	927:934	arg1	bioplastic					943:952	The produced virgin bioplastic	923:952	The produced virgin bioplastic	923:952	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	7	43	theme	burial	1414:1419	arg1	test					1421:1424	soil burial test	1409:1424	soil burial test	1409:1424	The biodegradability feature was further highlighted through soil burial test.					
37217054	1	44	theme	bioplastic	322:331	arg1	production					333:342	biodegradable bioplastic production	308:342	biodegradable bioplastic production from renewable resources	308:367	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	0	45	theme	smart	145:149	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	45	theme	smart	145:149	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	5	46	theme	virgin	936:941	arg1	bioplastic					943:952	The produced virgin bioplastic	923:952	The produced virgin bioplastic	923:952	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	4	47	theme	bioplastic	900:909	arg1	production					911:920	bioplastic production	900:920	bioplastic production	900:920	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	5	48	theme	physical	971:978	arg1	modification					980:991	physical modification	971:991	physical modification through the introduction of plasticizers such as glycerol	971:1049	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	1	49	theme	non-biodegradable	215:231	arg1	plastic					233:239	non-biodegradable plastic	215:239	non-biodegradable plastic	215:239	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	0	50	theme	auto-detecting	130:143	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	50	theme	auto-detecting	130:143	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	8	51	theme	minute	1586:1591	arg1	introduction					1593:1604	the minute introduction	1582:1604	the minute introduction of plant-derived anthocyanin extract into it	1582:1649	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	5	52	theme	plasticizers	1021:1032	arg1	introduction					1005:1016	the introduction	1001:1016	the introduction of plasticizers such as glycerol	1001:1049	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	2	53	theme	packaging	450:458	arg1	materials					460:468	packaging materials	450:468	packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions	450:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	0	54	theme	acid	57:60	arg1	bioplastic					36:45	A mechanically robust biodegradable bioplastic	0:45	A mechanically robust biodegradable bioplastic of citric acid	0:60	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	3	55	theme	real-world	726:735	arg1	scenarios					737:745	real-world scenarios	726:745	real-world scenarios	726:745	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	6	56	theme	possible	1318:1325	arg1	strength					1271:1278	maximum tensile strength	1255:1278	maximum tensile strength of 24.60 MPa	1255:1291	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	6	56	theme	possible	1318:1325	arg1	result					1340:1345	the best possible experimental result	1309:1345	the best possible experimental result	1309:1345	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	8	57	theme	protection	1481:1490	arg1	function					1452:1459	their general function	1438:1459	their general function of preservation and protection	1438:1490	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	0	58	theme	citric	50:55	arg1	acid					57:60	citric acid	50:60	citric acid	50:60	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	1	59	theme	renewable	349:357	arg1	resources					359:367	renewable resources	349:367	renewable resources	349:367	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	9	60	theme	food	1812:1815	arg1	material					1827:1834	a smart food packaging material	1804:1834	a smart food packaging material	1804:1834	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	9	61	contain	has	1776:1778	arg1	film					1689:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film	1652:1692	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	9	61	contain	has	1776:1778	arg2	potential					1780:1788	potential	1780:1788	potential	1780:1788	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	2	62	theme	bioplastics	377:387	arg1	option					439:444	a viable option	430:444	a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions	430:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	2	62	theme	bioplastics	377:387	arg1	production					389:398	Starch bioplastics production	370:398	Starch bioplastics production from underutilized sources	370:425	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	8	63	theme	pH-sensitive	1537:1548	arg1	spoilage					1555:1562	pH-sensitive food spoilage	1537:1562	pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it	1537:1649	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	5	64	theme	desired	1124:1130	arg1	film					1150:1153	the desired starch bioplastic film	1120:1153	the desired starch bioplastic film	1120:1153	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	3	65	theme	potential	699:707	arg1	applicability					709:721	its potential applicability	695:721	its potential applicability	695:721	Pristine bioplastic production results in some undesirable qualities and hence requires further modification in order to elevate its potential applicability in real-world scenarios.					
37217054	6	66	theme	experimental	1327:1338	arg1	strength					1271:1278	maximum tensile strength	1255:1278	maximum tensile strength of 24.60 MPa	1255:1291	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	6	66	theme	experimental	1327:1338	arg1	result					1340:1345	the best possible experimental result	1309:1345	the best possible experimental result	1309:1345	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	2	67	theme	Starch	370:375	arg1	option					439:444	a viable option	430:444	a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions	430:563	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	2	67	theme	Starch	370:375	arg1	production					389:398	Starch bioplastics production	370:398	Starch bioplastics production from underutilized sources	370:425	Starch bioplastics production from underutilized sources is a viable option for packaging materials that are non-toxic, environmentally benign, and easily biodegradable under disposed conditions.					
37217054	8	68	theme	preservation	1464:1475	arg1	function					1452:1459	their general function	1438:1459	their general function of preservation and protection	1438:1490	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	6	69	theme	tensile	1263:1269	arg1	strength					1271:1278	maximum tensile strength	1255:1278	maximum tensile strength of 24.60 MPa	1255:1291	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	6	69	theme	tensile	1263:1269	arg1	result					1340:1345	the best possible experimental result	1309:1345	the best possible experimental result	1309:1345	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	5	70	theme	starch	1132:1137	arg1	film					1150:1153	the desired starch bioplastic film	1120:1153	the desired starch bioplastic film	1120:1153	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	6	71	theme	24.60 MPa	1283:1291	arg1	strength					1271:1278	maximum tensile strength	1255:1278	maximum tensile strength of 24.60 MPa	1255:1291	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	6	71	theme	24.60 MPa	1283:1291	arg1	result					1340:1345	the best possible experimental result	1309:1345	the best possible experimental result	1309:1345	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	9	72	theme	extreme	1735:1741	arg1	change					1743:1748	an extreme change	1732:1748	an extreme change in the pH value	1732:1764	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
37217054	4	73	theme	local	794:798	arg1	yams					811:814	yams	811:814	yams	811:814	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	4	73	theme	local	794:798	arg1	variety					800:806	a local variety	792:806	a local variety of yams	792:814	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	8	74	theme	general	1444:1450	arg1	function					1452:1459	their general function	1438:1459	their general function of preservation and protection	1438:1490	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	1	75	theme	depleting	245:253	arg1	resources					269:277	depleting non-renewable resources	245:277	depleting non-renewable resources	245:277	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	0	76	theme	plasticized	71:81	arg1	starch					87:92	plasticized yam starch	71:92	plasticized yam starch	71:92	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	0	76	theme	plasticized	71:81	arg1	film					151:154	a fish spoilage auto-detecting smart film	114:154	a fish spoilage auto-detecting smart film	114:154	A mechanically robust biodegradable bioplastic of citric acid modified plasticized yam starch with anthocyanin as a fish spoilage auto-detecting smart film.					
37217054	5	77	theme	bioplastic	1139:1148	arg1	film					1150:1153	the desired starch bioplastic film	1120:1153	the desired starch bioplastic film	1120:1153	The produced virgin bioplastic was subjected to physical modification through the introduction of plasticizers such as glycerol, while citric acid (CA) was employed as modifier in order to produce the desired starch bioplastic film.					
37217054	8	78	theme	spoilage	1555:1562	arg1	detection					1564:1572	pH-sensitive food spoilage detection	1537:1572	pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it	1537:1649	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	6	79	theme	bioplastics	1193:1203	arg1	compositions					1170:1181	The different compositions	1156:1181	The different compositions of starch bioplastics	1156:1203	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	1	80	theme	non-renewable	255:267	arg1	resources					269:277	depleting non-renewable resources	245:277	depleting non-renewable resources	245:277	The current scenario of environmental pollution caused by non-biodegradable plastic and depleting non-renewable resources has called upon the need for biodegradable bioplastic production from renewable resources.					
37217054	6	81	theme	mechanical	1229:1238	arg1	properties					1240:1249	their mechanical properties	1223:1249	their mechanical properties	1223:1249	The different compositions of starch bioplastics were analyzed for their mechanical properties and maximum tensile strength of 24.60 MPa was observed as the best possible experimental result.					
37217054	8	82	theme	food	1550:1553	arg1	spoilage					1555:1562	pH-sensitive food spoilage	1537:1562	pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it	1537:1649	Apart from their general function of preservation and protection, the produced bioplastic can be employed for pH-sensitive food spoilage detection through the minute introduction of plant-derived anthocyanin extract into it.					
37217054	4	83	theme	yam	762:764	arg1	starch					766:771	yam starch	762:771	yam starch	762:771	In this work, yam starch was extracted from a local variety of yams through an eco-friendly and energy-efficient process which was further utilized for bioplastic production.					
37217054	9	84	theme	packaging	1817:1825	arg1	material					1827:1834	a smart food packaging material	1804:1834	a smart food packaging material	1804:1834	The produced pH-sensitive bioplastic film showed distinct changes in color upon an extreme change in the pH value and hence has potential to be used as a smart food packaging material.					
36239887	0	0	theme	membrane	59:66	arg1	strategy					7:14	Design strategy	0:14	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.	0:125	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	3	1	theme	effective	632:640	arg1	strategy					655:662	a simple but effective step-by-step strategy	619:662	a simple but effective step-by-step strategy	619:662	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	7	2	theme	@	1276:1276	arg1	composite					1289:1297	BC@MIL-100(Fe) composite	1274:1297	BC@MIL-100(Fe) composite	1274:1297	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	2	3	theme	PPCPs	314:318	arg1	kind					298:301	a kind	296:301	a kind of harmful PPCPs	296:318	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	2	3	theme	PPCPs	314:318	arg1	diclofenac					321:330	diclofenac sodium (DCF)	321:343	diclofenac sodium (DCF)	321:343	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	1	4	theme	extensive	223:231	arg1	attention					233:241	extensive attention	223:241	extensive attention	223:241	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	0	5	theme	composite	49:57	arg1	membrane					59:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	7	6	theme	adsorption	1311:1320	arg1	efficiency					1322:1331	high adsorption efficiency	1306:1331	high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption	1306:1428	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	6	7	theme	equilibrium	1157:1167	arg1	30 min					1175:1180	30 min	1175:1180	30 min	1175:1180	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	7	theme	equilibrium	1157:1167	arg1	time					1169:1172	short equilibrium time	1151:1172	short equilibrium time (30 min)	1151:1181	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	2	8	theme	harmful	306:312	arg1	PPCPs					314:318	harmful PPCPs	306:318	harmful PPCPs	306:318	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	8	9	theme	electrostatic	1539:1551	arg1	interaction					1553:1563	electrostatic interaction	1539:1563	electrostatic interaction	1539:1563	The results demonstrated that the adsorption mechanism may involve π-π interaction, H-bond interaction, and electrostatic interaction.					
36239887	8	10	theme	adsorption	1465:1474	arg1	mechanism					1476:1484	the adsorption mechanism	1461:1484	the adsorption mechanism	1461:1484	The results demonstrated that the adsorption mechanism may involve π-π interaction, H-bond interaction, and electrostatic interaction.					
36239887	4	11	theme	obvious	860:866	arg1	structure					879:887	obvious core-shell structure	860:887	obvious core-shell structure	860:887	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	3	12	theme	simple	621:626	arg1	strategy					655:662	a simple but effective step-by-step strategy	619:662	a simple but effective step-by-step strategy	619:662	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	6	13	theme	short	1151:1155	arg1	30 min					1175:1180	30 min	1175:1180	30 min	1175:1180	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	13	theme	short	1151:1155	arg1	time					1169:1172	short equilibrium time	1151:1172	short equilibrium time (30 min)	1151:1181	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	14	theme	BC	1056:1057	arg1	membrane					1081:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	3	15	theme	composite	488:496	arg1	membranes					498:506	network structure composite membranes	470:506	network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	470:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	5	16	theme	@	910:910	arg1	MIL-100					911:917	the BC@MIL-100	904:917	the BC@MIL-100(Fe)	904:921	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	5	16	theme	@	910:910	arg1	Fe					919:920	Fe	919:920	Fe	919:920	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	4	17	theme	@	671:671	arg1	membrane					694:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	6	18	theme	composite	1071:1079	arg1	membrane					1081:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	4	19	theme	Fe	680:681	arg1	membrane					694:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	0	20	from	water	120:124	arg1	removal					86:92	the efficient removal	72:92	the efficient removal of diclofenac sodium from water	72:124	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	7	21	theme	high	1306:1309	arg1	efficiency					1322:1331	high adsorption efficiency	1306:1331	high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption	1306:1428	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	7	22	theme	DCF	1246:1248	arg1	solution					1264:1271	low DCF concentration solution	1242:1271	low DCF concentration solution	1242:1271	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	2	23	dep	diclofenac	321:330	arg1	DCF					340:342	DCF	340:342	DCF	340:342	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	2	23	dep	diclofenac	321:330	arg1	sodium					332:337	sodium	332:337	diclofenac sodium (DCF)	321:343	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	1	24	theme	personal	147:154	arg1	products					161:168	personal care products	147:168	personal care products (PPCPs)	147:176	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	1	24	theme	personal	147:154	arg1	PPCPs					171:175	PPCPs	171:175	PPCPs	171:175	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	0	25	theme	efficient	76:84	arg1	removal					86:92	the efficient removal	72:92	the efficient removal of diclofenac sodium from water	72:124	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	3	26	theme	step-by-step	642:653	arg1	strategy					655:662	a simple but effective step-by-step strategy	619:662	a simple but effective step-by-step strategy	619:662	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	7	27	theme	successive	1388:1397	arg1	adsorptions					1399:1409	five successive adsorptions	1383:1409	five successive adsorptions without desorption	1383:1428	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	3	28	theme	structure	478:486	arg1	membranes					498:506	network structure composite membranes	470:506	network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	470:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	1	29	theme	care	156:159	arg1	products					161:168	personal care products	147:168	personal care products (PPCPs)	147:176	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	1	29	theme	care	156:159	arg1	PPCPs					171:175	PPCPs	171:175	PPCPs	171:175	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	6	30	theme	as-obtained	1044:1054	arg1	membrane					1081:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	31	theme	chemical	1127:1134	arg1	stability					1136:1144	high chemical stability	1122:1144	high chemical stability	1122:1144	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	3	32	theme	one-dimensional	522:536	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	0	33	theme	Design	0:5	arg1	strategy					7:14	Design strategy	0:14	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.	0:125	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	6	34	theme	high	1122:1125	arg1	stability					1136:1144	high chemical stability	1122:1144	high chemical stability	1122:1144	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	7	35	theme	periodic	1336:1343	arg1	test					1345:1348	periodic test	1336:1348	periodic test	1336:1348	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	4	36	theme	BC	669:670	arg1	membrane					694:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	2	37	theme	water	377:381	arg1	environment					383:393	water environment	377:393	water environment	377:393	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	0	38	theme	diclofenac	97:106	arg1	sodium					108:113	diclofenac sodium	97:113	diclofenac sodium	97:113	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	7	39	theme	concentration	1250:1262	arg1	solution					1264:1271	low DCF concentration solution	1242:1271	low DCF concentration solution	1242:1271	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	4	40	theme	cellulose	753:761	arg1	nanofiber					763:771	bacterial cellulose nanofiber	743:771	bacterial cellulose nanofiber	743:771	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	7	41	theme	BC	1274:1275	arg1	composite					1289:1297	BC@MIL-100(Fe) composite	1274:1297	BC@MIL-100(Fe) composite	1274:1297	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	3	42	theme	network	470:476	arg1	structure					478:486	network structure	470:486	network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	470:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	0	43	theme	@	36:36	arg1	membrane					59:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	1	44	theme	human	263:267	arg1	health					269:274	human health	263:274	human health	263:274	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	6	45	theme	adsorption	1193:1202	arg1	296 mg g-1					1214:1223	296 mg g-1	1214:1223	296 mg g-1	1214:1223	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	45	theme	adsorption	1193:1202	arg1	capacity					1204:1211	high adsorption capacity	1188:1211	high adsorption capacity (296 mg g-1)	1188:1224	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	2	46	located	detected	365:372	arg1	environment					383:393	water environment	377:393	water environment	377:393	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	2	46	located	detected	365:372	arg2	diclofenac					321:330	diclofenac sodium (DCF)	321:343	diclofenac sodium (DCF)	321:343	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	2	46	located	detected	365:372	arg2	kind					298:301	a kind	296:301	a kind of harmful PPCPs	296:318	As a kind of harmful PPCPs, diclofenac sodium (DCF) has been frequently detected in water environment, which needs to be removed effectively.					
36239887	3	47	theme	well-defined	543:554	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	6	48	theme	Fe	1067:1068	arg1	membrane					1081:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	7	49	theme	Fe	1285:1286	arg1	composite					1289:1297	BC@MIL-100(Fe) composite	1274:1297	BC@MIL-100(Fe) composite	1274:1297	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	0	50	theme	BC	34:35	arg1	membrane					59:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	0	51	theme	sodium	108:113	arg1	removal					86:92	the efficient removal	72:92	the efficient removal of diclofenac sodium from water	72:124	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	5	52	theme	good	982:985	arg1	properties					987:996	good properties	982:996	good properties	982:996	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	0	53	theme	self-assembled	19:32	arg1	membrane					59:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	1	54	theme	typical	181:187	arg1	pollutant					198:206	typical emerging pollutant	181:206	typical emerging pollutant	181:206	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	3	55	theme	@	591:591	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	6	56	theme	convenient	1100:1109	arg1	recycling					1111:1119	convenient recycling	1100:1119	convenient recycling	1100:1119	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	9	57	theme	new	1589:1591	arg1	finding					1593:1599	the new finding	1585:1599	the new finding to understand the removing of DCF from water environment	1585:1656	This work proposes the new finding to understand the removing of DCF from water environment.					
36239887	5	58	contain	possessed	932:940	arg1	MIL-100					911:917	the BC@MIL-100	904:917	the BC@MIL-100(Fe)	904:921	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	5	58	contain	possessed	932:940	arg1	Fe					919:920	Fe	919:920	Fe	919:920	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	5	58	contain	possessed	932:940	arg2	architecture					952:963	favorable architecture	942:963	favorable architecture	942:963	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	5	59	theme	favorable	942:950	arg1	architecture					952:963	favorable architecture	942:963	favorable architecture	942:963	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	9	60	theme	water	1640:1644	arg1	environment					1646:1656	water environment	1640:1656	water environment	1640:1656	This work proposes the new finding to understand the removing of DCF from water environment.					
36239887	4	61	theme	bacterial	743:751	arg1	nanofiber					763:771	bacterial cellulose nanofiber	743:771	bacterial cellulose nanofiber	743:771	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	8	62	theme	π-π	1498:1500	arg1	interaction					1502:1512	π-π interaction	1498:1512	π-π interaction	1498:1512	The results demonstrated that the adsorption mechanism may involve π-π interaction, H-bond interaction, and electrostatic interaction.					
36239887	5	63	theme	BC	908:909	arg1	MIL-100					911:917	the BC@MIL-100	904:917	the BC@MIL-100(Fe)	904:921	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	5	63	theme	BC	908:909	arg1	Fe					919:920	Fe	919:920	Fe	919:920	Impressively, the BC@MIL-100(Fe) not only possessed favorable architecture but also behaved good properties to adsorb DCF from water.					
36239887	4	64	theme	three-dimensional	707:723	arg1	network					725:731	three-dimensional network	707:731	three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure	707:887	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	3	65	theme	core-shell	556:565	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	6	66	theme	high	1188:1191	arg1	296 mg g-1					1214:1223	296 mg g-1	1214:1223	296 mg g-1	1214:1223	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	6	66	theme	high	1188:1191	arg1	capacity					1204:1211	high adsorption capacity	1188:1211	high adsorption capacity (296 mg g-1)	1188:1224	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	7	67	from	efficiency	1322:1331	arg1	test					1345:1348	periodic test	1336:1348	periodic test	1336:1348	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	1	68	theme	emerging	189:196	arg1	pollutant					198:206	typical emerging pollutant	181:206	typical emerging pollutant	181:206	Pharmaceuticals and personal care products (PPCPs) as typical emerging pollutant have attracted extensive attention due to the risks to human health and environment.					
36239887	4	69	theme	composite	684:692	arg1	membrane					694:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	3	70	theme	Fe	601:602	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	3	71	theme	BC	588:589	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	7	72	theme	low	1242:1244	arg1	solution					1264:1271	low DCF concentration solution	1242:1271	low DCF concentration solution	1242:1271	Strikingly, in low DCF concentration solution, BC@MIL-100(Fe) composite showed high adsorption efficiency in periodic test, which can still reach 70% after five successive adsorptions without desorption.					
36239887	8	73	theme	H-bond	1515:1520	arg1	interaction					1522:1532	H-bond interaction	1515:1532	H-bond interaction	1515:1532	The results demonstrated that the adsorption mechanism may involve π-π interaction, H-bond interaction, and electrostatic interaction.					
36239887	3	74	theme	bacterial	567:575	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	6	75	theme	@	1058:1058	arg1	membrane					1081:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	the as-obtained BC@MIL-100(Fe) composite membrane	1040:1088	As we expected, the as-obtained BC@MIL-100(Fe) composite membrane exhibited convenient recycling, high chemical stability, and short equilibrium time (30 min) with high adsorption capacity (296 mg g-1).					
36239887	4	76	contain	has	703:705	arg2	network					725:731	three-dimensional network	707:731	three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure	707:887	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	4	76	contain	has	703:705	arg1	membrane					694:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane	665:701	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36239887	0	77	theme	Fe	45:46	arg1	membrane					59:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	self-assembled BC@MIL-100(Fe) composite membrane	19:66	Design strategy of self-assembled BC@MIL-100(Fe) composite membrane for the efficient removal of diclofenac sodium from water.					
36239887	3	78	theme	cellulose	577:585	arg1	nanofibers					605:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers	522:614	Herein, we successfully fabricated network structure composite membranes consisting of one-dimensional (1D) well-defined core-shell bacterial cellulose (BC)@MIL-100 (Fe) nanofibers by a simple but effective step-by-step strategy.					
36239887	4	79	theme	core-shell	868:877	arg1	structure					879:887	obvious core-shell structure	860:887	obvious core-shell structure	860:887	The BC@MIL-100(Fe) composite membrane has three-dimensional network utilizing bacterial cellulose nanofiber as template, which was observed as the MIL-100(Fe) grew on the nanofiber uniformly and obvious core-shell structure.					
36235274	3	0	theme	hydrophobic	595:605	arg1	materials					607:615	more hydrophobic materials	590:615	more hydrophobic materials	590:615	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	2	1	theme	sorption	519:526	arg1	DVS					529:531	dynamic vapor sorption (DVS)	505:532	dynamic vapor sorption (DVS)	505:532	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	1	2	theme	TPS	153:155	arg1	materials					158:166	thermoplastic starch (TPS) materials	131:166	thermoplastic starch (TPS) materials for food packaging	131:185	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	4	3	theme	FT-IR	747:751	arg1	study					753:757	FT-IR study	747:757	FT-IR study of the material surface and inner core	747:796	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	3	4	theme	%	708:708	arg1	blend					715:719	the 2%-FASE blend	703:719	the 2%-FASE blend	703:719	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	3	5	dep	ratio	636:640	arg1	whatever					618:625	whatever	618:625	whatever	618:625	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	2	6	theme	vapor	513:517	arg1	DVS					529:531	dynamic vapor sorption (DVS)	505:532	dynamic vapor sorption (DVS)	505:532	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	2	7	theme	ratios	322:327	arg1	total					297:301	A total	295:301	A total of three different ratios of FASE (2%, 5% and 10%)	295:352	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	4	8	theme	hydrophobicity	901:914	arg1	increase					872:879	the increase	868:879	the increase of material surface hydrophobicity	868:914	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	3	9	theme	-FASE	709:713	arg1	blend					715:719	the 2%-FASE blend	703:719	the 2%-FASE blend	703:719	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	4	10	theme	core	793:796	arg1	study					753:757	FT-IR study	747:757	FT-IR study of the material surface and inner core	747:796	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	2	11	theme	dynamic	505:511	arg1	DVS					529:531	dynamic vapor sorption (DVS)	505:532	dynamic vapor sorption (DVS)	505:532	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	2	12	theme	behaviors	547:555	arg1	properties					444:453	physico-chemical properties	427:453	physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	427:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	3	13	theme	10	736:737	arg1	%					738:738	%	738:738	%	738:738	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	1	14	theme	starch	234:239	arg1	esters					206:211	fatty acid starch esters	188:211	fatty acid starch esters (FASE)	188:218	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	14	theme	starch	234:239	arg1	tri-laurate					241:251	starch tri-laurate	234:251	specifically starch tri-laurate	221:251	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	2	15	theme	physico-chemical	427:442	arg1	properties					444:453	physico-chemical properties	427:453	physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	427:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	6	16	theme	materials	1122:1130	arg1	properties					1095:1104	tensile properties	1087:1104	tensile properties of starch-based materials with humidity rate	1087:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	2	17	theme	tensile	539:545	arg1	behaviors					547:555	tensile behaviors	539:555	tensile behaviors	539:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	3	18	theme	2	707:707	arg1	%					708:708	%	708:708	%	708:708	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	2	19	theme	different	312:320	arg1	ratios					322:327	three different ratios	306:327	three different ratios of FASE (2%, 5% and 10%)	306:352	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	6	20	theme	starch-based	1109:1120	arg1	materials					1122:1130	starch-based materials	1109:1130	starch-based materials with humidity rate	1109:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	3	21	with	TPS	567:569	arg1	FASE					576:579	FASE	576:579	FASE	576:579	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	5	22	theme	surface	930:936	arg1	hydrophobicity					938:951	this surface hydrophobicity	925:951	this surface hydrophobicity	925:951	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	2	23	theme	FASE	417:420	arg1	influence					404:412	the influence	400:412	the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	400:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	5	24	theme	blending	954:961	arg1	TPS					963:965	blending TPS	954:965	blending TPS with FASE	954:975	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	6	25	theme	FASE	1255:1258	arg1	%					1267:1267	FASE ratio 2%	1255:1267	FASE ratio 2%	1255:1267	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	2	26	dep	FASE	332:335	arg1	%					339:339	2%	338:339	2%	338:339	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	2	26	dep	FASE	332:335	arg1	%					343:343	5%	342:343	5%	342:343	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	2	26	dep	FASE	332:335	arg1	%					351:351	10%	349:351	10%	349:351	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	2	27	dep	blends	467:472	arg1	i.e.					475:478	TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	458:555	i.e.	475:478	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	6	28	theme	stress	1221:1226	arg1	decrease					1201:1208	a decrease	1199:1208	a decrease of maximal stress of 10-30%	1199:1236	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	2	29	theme	DVS	529:531	arg1	properties					444:453	physico-chemical properties	427:453	physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	427:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	5	30	theme	sorption	1009:1016	arg1	behavior					1018:1025	blend vapor sorption behavior	997:1025	blend vapor sorption behavior	997:1025	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	5	31	theme	vapor	1003:1007	arg1	behavior					1018:1025	blend vapor sorption behavior	997:1025	blend vapor sorption behavior	997:1025	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	1	32	theme	food	172:175	arg1	packaging					177:185	food packaging	172:185	food packaging	172:185	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	6	33	theme	FASE	1187:1190	arg1	ratio					1192:1196	FASE ratio	1187:1196	FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%)	1187:1276	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	3	34	dep	leads	581:585	arg1	ratio					636:640	the FASE ratio	627:640	the FASE ratio	627:640	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	6	35	theme	tensile	1087:1093	arg1	properties					1095:1104	tensile properties	1087:1104	tensile properties of starch-based materials with humidity rate	1087:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	6	36	theme	humidity	1137:1144	arg1	rate					1146:1149	humidity rate	1137:1149	humidity rate	1137:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	4	37	theme	material	766:773	arg1	surface					775:781	the material surface	762:781	the material surface	762:781	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	6	38	theme	%	1236:1236	arg1	stress					1221:1226	maximal stress	1213:1226	maximal stress of 10-30%	1213:1236	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	6	39	theme	ratio	1260:1264	arg1	%					1267:1267	FASE ratio 2%	1255:1267	FASE ratio 2%	1255:1267	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	3	40	theme	FASE	631:634	arg1	ratio					636:640	the FASE ratio	627:640	the FASE ratio	627:640	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	2	41	theme	blends	467:472	arg1	properties					444:453	physico-chemical properties	427:453	physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	427:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	1	42	theme	fatty	188:192	arg1	FASE					214:217	FASE	214:217	FASE	214:217	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	42	theme	fatty	188:192	arg1	esters					206:211	fatty acid starch esters	188:211	fatty acid starch esters (FASE)	188:218	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	42	theme	fatty	188:192	arg1	tri-laurate					241:251	starch tri-laurate	234:251	specifically starch tri-laurate	221:251	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	0	43	theme	Starch	46:51	arg1	Hydrophobization					12:27	the Hydrophobization	8:27	the Hydrophobization of Thermoplastic Starch	8:51	Towards the Hydrophobization of Thermoplastic Starch Using Fatty Acid Starch Ester as Additive.					
36235274	2	44	theme	TPS/FASE	458:465	arg1	blends					467:472	TPS/FASE blends	458:472	TPS/FASE blends	458:472	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	6	45	theme	properties	1095:1104	arg1	variability					1072:1082	the variability	1068:1082	the variability of tensile properties of starch-based materials with humidity rate	1068:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	1	46	theme	acid	194:197	arg1	FASE					214:217	FASE	214:217	FASE	214:217	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	46	theme	acid	194:197	arg1	esters					206:211	fatty acid starch esters	188:211	fatty acid starch esters (FASE)	188:218	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	46	theme	acid	194:197	arg1	tri-laurate					241:251	starch tri-laurate	234:251	specifically starch tri-laurate	221:251	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	0	47	theme	Thermoplastic	32:44	arg1	Starch					46:51	Thermoplastic Starch	32:51	Thermoplastic Starch	32:51	Towards the Hydrophobization of Thermoplastic Starch Using Fatty Acid Starch Ester as Additive.					
36235274	1	48	theme	TPS	277:279	arg1	formulations					281:292	TPS formulations	277:292	TPS formulations	277:292	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	4	49	theme	surface	775:781	arg1	study					753:757	FT-IR study	747:757	FT-IR study of the material surface and inner core	747:796	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	3	50	dep	90°	695:697	arg1	99°					724:726	99°	724:726	99°	724:726	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	3	50	dep	90°	695:697	arg1	to					721:722	to	721:722	to	721:722	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	1	51	theme	starch	199:204	arg1	FASE					214:217	FASE	214:217	FASE	214:217	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	51	theme	starch	199:204	arg1	esters					206:211	fatty acid starch esters	188:211	fatty acid starch esters (FASE)	188:218	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	1	51	theme	starch	199:204	arg1	tri-laurate					241:251	starch tri-laurate	234:251	specifically starch tri-laurate	221:251	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	2	52	theme	TPS	372:374	arg1	formulation					376:386	the TPS formulation	368:386	the TPS formulation	368:386	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	3	53	theme	contact	667:673	arg1	angles					675:680	initially measured contact angles	648:680	initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend	648:744	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	2	54	theme	hydrophobicity	489:502	arg1	properties					444:453	physico-chemical properties	427:453	physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors	427:555	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	0	55	theme	Acid	65:68	arg1	Ester					77:81	Fatty Acid Starch Ester	59:81	Fatty Acid Starch Ester	59:81	Towards the Hydrophobization of Thermoplastic Starch Using Fatty Acid Starch Ester as Additive.					
36235274	6	56	theme	maximal	1213:1219	arg1	stress					1221:1226	maximal stress	1213:1226	maximal stress of 10-30%	1213:1236	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	1	57	theme	surface	105:111	arg1	hydrophobicity					113:126	surface hydrophobicity	105:126	surface hydrophobicity	105:126	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	4	58	theme	material	839:846	arg1	surface					848:854	the material surface	835:854	the material surface	835:854	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	5	59	theme	blend	997:1001	arg1	behavior					1018:1025	blend vapor sorption behavior	997:1025	blend vapor sorption behavior	997:1025	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	2	60	theme	surface	481:487	arg1	hydrophobicity					489:502	surface hydrophobicity	481:502	surface hydrophobicity	481:502	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	4	61	from	surface	848:854	arg1	located					824:830	located	824:830	located	824:830	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	6	62	theme	ductile	1295:1301	arg1	materials					1303:1311	more ductile materials	1290:1311	more ductile materials	1290:1311	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	3	63	theme	measured	658:665	arg1	angles					675:680	initially measured contact angles	648:680	initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend	648:744	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	4	64	located	located	824:830	arg1	surface					848:854	the material surface	835:854	the material surface	835:854	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	4	64	located	located	824:830	arg2	FASE					809:812	FASE	809:812	FASE	809:812	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	5	65	with	TPS	963:965	arg1	FASE					972:975	FASE	972:975	FASE	972:975	Despite this surface hydrophobicity, blending TPS with FASE seems not to affect blend vapor sorption behavior.					
36235274	3	66	theme	Blending	558:565	arg1	TPS					567:569	Blending TPS	558:569	Blending TPS with FASE	558:579	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	6	67	theme	behavior	1046:1053	arg1	perspective					1055:1065	a mechanical behavior perspective	1033:1065	a mechanical behavior perspective	1033:1065	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	1	68	theme	thermoplastic	131:143	arg1	materials					158:166	thermoplastic starch (TPS) materials	131:166	thermoplastic starch (TPS) materials for food packaging	131:185	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	6	69	dep	ratio	1192:1196	arg1	observed					1242:1249	observed	1242:1249	was observed for FASE ratio 2% and 10%	1238:1275	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	0	70	theme	Starch	70:75	arg1	Ester					77:81	Fatty Acid Starch Ester	59:81	Fatty Acid Starch Ester	59:81	Towards the Hydrophobization of Thermoplastic Starch Using Fatty Acid Starch Ester as Additive.					
36235274	4	71	theme	surface	893:899	arg1	hydrophobicity					901:914	material surface hydrophobicity	884:914	material surface hydrophobicity	884:914	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	6	72	theme	mechanical	1035:1044	arg1	perspective					1055:1065	a mechanical behavior perspective	1033:1065	a mechanical behavior perspective	1033:1065	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	4	73	theme	material	884:891	arg1	hydrophobicity					901:914	material surface hydrophobicity	884:914	material surface hydrophobicity	884:914	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
36235274	1	74	theme	starch	145:150	arg1	materials					158:166	thermoplastic starch (TPS) materials	131:166	thermoplastic starch (TPS) materials for food packaging	131:185	To bring surface hydrophobicity to thermoplastic starch (TPS) materials for food packaging, fatty acid starch esters (FASE), specifically starch tri-laurate, were incorporated into TPS formulations.					
36235274	6	75	with	materials	1122:1130	arg1	rate					1146:1149	humidity rate	1137:1149	humidity rate	1137:1149	From a mechanical behavior perspective, the variability of tensile properties of starch-based materials with humidity rate is slightly reduced with increasing FASE ratio (a decrease of maximal stress of 10-30% was observed for FASE ratio 2% and 10%), leading to more ductile materials.					
36235274	0	76	theme	Fatty	59:63	arg1	Ester					77:81	Fatty Acid Starch Ester	59:81	Fatty Acid Starch Ester	59:81	Towards the Hydrophobization of Thermoplastic Starch Using Fatty Acid Starch Ester as Additive.					
36235274	2	77	theme	FASE	332:335	arg1	ratios					322:327	three different ratios	306:327	three different ratios of FASE (2%, 5% and 10%)	306:352	A total of three different ratios of FASE (2%, 5% and 10%) were added to the TPS formulation to evaluate the influence of FASE onto physico-chemical properties of TPS/FASE blends, i.e., surface hydrophobicity, dynamic vapor sorption (DVS), and tensile behaviors.					
36235274	3	78	theme	%	738:738	arg1	-blend					739:744	the 10%-blend	732:744	the 10%-blend	732:744	Blending TPS with FASE leads to more hydrophobic materials, whatever the FASE ratio, with initially measured contact angles ranging from 90° for the 2%-FASE blend to 99° for the 10%-blend.					
36235274	4	79	theme	inner	787:791	arg1	core					793:796	inner core	787:796	inner core	787:796	FT-IR study of the material surface and inner core shows that FASE is mainly located at the material surface, justifying the increase of material surface hydrophobicity.					
37321752	0	0	theme	sensors	109:115	arg1	design					117:122	sensors design	109:122	sensors design	109:122	Polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) modified cellulose as promising material for sensors design.					
37321752	2	1	theme	thermal	389:395	arg1	stability					397:405	thermal stability	389:405	thermal stability	389:405	The morphology, mechanical properties, thermal stability, and electrical conductivity were investigated by means of several complementary techniques.					
37321752	4	2	theme	promising	636:644	arg1	performance					646:656	the promising performance	632:656	the promising performance of this material	632:673	Based on the promising performance of this material, novel device functions and wearable applications have been tested.					
37321752	3	3	theme	Cell/PANI-PAMPSA	561:576	arg1	composite					578:586	the Cell/PANI-PAMPSA composite	557:586	the Cell/PANI-PAMPSA composite	557:586	The obtained results highlight the excellent features of the Cell/PANI-PAMPSA composite with respect to the Cell/PANI one.					
37321752	1	4	theme	cellulose	296:304	arg1	aniline					314:320	aniline	314:320	aniline	314:320	A material based on cellulose coated with polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA) was synthesized in a simple way starting from cellulose fibres, aniline and using PAMPSA as dopant.					
37321752	1	4	theme	cellulose	296:304	arg1	fibres					306:311	cellulose fibres	296:311	cellulose fibres	296:311	A material based on cellulose coated with polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA) was synthesized in a simple way starting from cellulose fibres, aniline and using PAMPSA as dopant.					
37321752	3	5	theme	Cell/PANI	608:616	arg1	one					618:620	the Cell/PANI one	604:620	the Cell/PANI one	604:620	The obtained results highlight the excellent features of the Cell/PANI-PAMPSA composite with respect to the Cell/PANI one.					
37321752	5	6	dep	sensors	835:841	arg1	ii					809:810	ii	809:810	ii	809:810	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	6	7	used	used	1050:1053	arg2	system					1034:1039	Cell/PANI-PAMPSA system	1017:1039	Cell/PANI-PAMPSA system	1017:1039	To our knowledge, this is the first time that Cell/PANI-PAMPSA system has been used for such applications.					
37321752	5	8	dep	rate	930:933	arg1	monitoring					959:968	activity monitoring	950:968	activity monitoring	950:968	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	2	9	theme	electrical	412:421	arg1	conductivity					423:434	electrical conductivity	412:434	electrical conductivity	412:434	The morphology, mechanical properties, thermal stability, and electrical conductivity were investigated by means of several complementary techniques.					
37321752	6	10	theme	first	1001:1005	arg1	time					1007:1010	the first time that Cell/PANI-PAMPSA system has been used for such applications	997:1075	the first time that Cell/PANI-PAMPSA system has been used for such applications	997:1075	To our knowledge, this is the first time that Cell/PANI-PAMPSA system has been used for such applications.					
37321752	6	10	theme	first	1001:1005	arg1	this					989:992	this	989:992	this	989:992	To our knowledge, this is the first time that Cell/PANI-PAMPSA system has been used for such applications.					
37321752	2	11	theme	complementary	474:486	arg1	techniques					488:497	several complementary techniques	466:497	several complementary techniques	466:497	The morphology, mechanical properties, thermal stability, and electrical conductivity were investigated by means of several complementary techniques.					
37321752	2	12	theme	several	466:472	arg1	techniques					488:497	several complementary techniques	466:497	several complementary techniques	466:497	The morphology, mechanical properties, thermal stability, and electrical conductivity were investigated by means of several complementary techniques.					
37321752	5	13	theme	possible	761:768	arg1	use					777:779	its possible single use	757:779	its possible single use as: i) humidity sensors and ii) disposable biomedical sensors	757:841	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	1	14	theme	2-acrylamido-2-methyl-1-propanesulfonic	185:223	arg1	polyaniline/poly					167:182	polyaniline/poly	167:182	polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA)	167:248	A material based on cellulose coated with polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA) was synthesized in a simple way starting from cellulose fibres, aniline and using PAMPSA as dopant.					
37321752	1	14	theme	2-acrylamido-2-methyl-1-propanesulfonic	185:223	arg1	acid					225:228	2-acrylamido-2-methyl-1-propanesulfonic acid	185:228	2-acrylamido-2-methyl-1-propanesulfonic acid	185:228	A material based on cellulose coated with polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA) was synthesized in a simple way starting from cellulose fibres, aniline and using PAMPSA as dopant.					
37321752	4	15	theme	device	682:687	arg1	functions					689:697	novel device functions	676:697	novel device functions	676:697	Based on the promising performance of this material, novel device functions and wearable applications have been tested.					
37321752	5	16	theme	activity	950:957	arg1	monitoring					959:968	activity monitoring	950:968	activity monitoring	950:968	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	5	17	theme	single	770:775	arg1	use					777:779	its possible single use	757:779	its possible single use as: i) humidity sensors and ii) disposable biomedical sensors	757:841	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	4	18	theme	wearable	703:710	arg1	applications					712:723	wearable applications	703:723	wearable applications	703:723	Based on the promising performance of this material, novel device functions and wearable applications have been tested.					
37321752	5	19	theme	disposable	813:822	arg1	sensors					835:841	disposable biomedical sensors	813:841	ii) disposable biomedical sensors	809:841	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	5	20	dep	sensors	797:803	arg1	i					785:785	i	785:785	i	785:785	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	6	21	theme	Cell/PANI-PAMPSA	1017:1032	arg1	system					1034:1039	Cell/PANI-PAMPSA system	1017:1039	Cell/PANI-PAMPSA system	1017:1039	To our knowledge, this is the first time that Cell/PANI-PAMPSA system has been used for such applications.					
37321752	5	22	theme	immediate	854:862	arg1	services					875:882	immediate diagnostic services	854:882	immediate diagnostic services as close to the patient	854:906	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	3	23	theme	obtained	504:511	arg1	results					513:519	The obtained results	500:519	The obtained results	500:519	The obtained results highlight the excellent features of the Cell/PANI-PAMPSA composite with respect to the Cell/PANI one.					
37321752	5	24	theme	biomedical	824:833	arg1	sensors					835:841	disposable biomedical sensors	813:841	ii) disposable biomedical sensors	809:841	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	2	25	theme	mechanical	366:375	arg1	properties					377:386	mechanical properties	366:386	mechanical properties	366:386	The morphology, mechanical properties, thermal stability, and electrical conductivity were investigated by means of several complementary techniques.					
37321752	4	26	theme	material	666:673	arg1	performance					646:656	the promising performance	632:656	the promising performance of this material	632:673	Based on the promising performance of this material, novel device functions and wearable applications have been tested.					
37321752	5	27	theme	diagnostic	864:873	arg1	services					875:882	immediate diagnostic services	854:882	immediate diagnostic services as close to the patient	854:906	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	3	28	theme	excellent	535:543	arg1	features					545:552	the excellent features	531:552	the excellent features of the Cell/PANI-PAMPSA composite	531:586	The obtained results highlight the excellent features of the Cell/PANI-PAMPSA composite with respect to the Cell/PANI one.					
37321752	1	29	theme	simple	271:276	arg1	way					278:280	a simple way	269:280	a simple way starting from cellulose fibres, aniline	269:320	A material based on cellulose coated with polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) (Cell/PANI-PAMPSA) was synthesized in a simple way starting from cellulose fibres, aniline and using PAMPSA as dopant.					
37321752	5	30	theme	humidity	788:795	arg1	sensors					797:803	humidity sensors	788:803	: i) humidity sensors	783:803	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
37321752	6	31	theme	such	1059:1062	arg1	applications					1064:1075	such applications	1059:1075	such applications	1059:1075	To our knowledge, this is the first time that Cell/PANI-PAMPSA system has been used for such applications.					
37321752	3	32	theme	composite	578:586	arg1	features					545:552	the excellent features	531:552	the excellent features of the Cell/PANI-PAMPSA composite	531:586	The obtained results highlight the excellent features of the Cell/PANI-PAMPSA composite with respect to the Cell/PANI one.					
37321752	4	33	theme	novel	676:680	arg1	functions					689:697	novel device functions	676:697	novel device functions	676:697	Based on the promising performance of this material, novel device functions and wearable applications have been tested.					
37321752	0	34	theme	promising	86:94	arg1	material					96:103	promising material	86:103	promising material for sensors design	86:122	Polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) modified cellulose as promising material for sensors design.					
37321752	0	35	theme	2-acrylamido-2-methyl-1-propanesulfonic	18:56	arg1	Polyaniline/poly					0:15	Polyaniline/poly	0:15	Polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid)	0:62	Polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) modified cellulose as promising material for sensors design.					
37321752	0	35	theme	2-acrylamido-2-methyl-1-propanesulfonic	18:56	arg1	acid					58:61	2-acrylamido-2-methyl-1-propanesulfonic acid	18:61	2-acrylamido-2-methyl-1-propanesulfonic acid	18:61	Polyaniline/poly (2-acrylamido-2-methyl-1-propanesulfonic acid) modified cellulose as promising material for sensors design.					
37321752	5	36	theme	heart	924:928	arg1	rate					930:933	heart rate	924:933	heart rate	924:933	We focused on its possible single use as: i) humidity sensors and ii) disposable biomedical sensors to provide immediate diagnostic services as close to the patient as possible for heart rate or respiration activity monitoring.					
35193017	0	0	theme	hydrophobic	99:109	arg1	peptides					111:118	hydrophobic peptides	99:118	hydrophobic peptides	99:118	Improving emulsifying properties of carboxylated microcrystalline cellulose by calcium bridging to hydrophobic peptides.					
35193017	5	1	theme	CC-Ca-HP	795:802	arg1	emulsion					804:811	the CC-Ca-HP emulsion	791:811	the CC-Ca-HP emulsion	791:811	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	5	2	theme	Further	664:670	arg1	analysis					672:679	Further analysis	664:679	Further analysis of the steady flow characteristics and dynamic viscoelastic properties	664:750	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	2	3	theme	successful	344:353	arg1	attachment					355:364	the successful attachment	340:364	the successful attachment of HP to CC	340:376	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	4	4	theme	emulsifying	598:608	arg1	stability					610:618	remarkable emulsifying stability	587:618	remarkable emulsifying stability	587:618	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
35193017	6	5	theme	gastrointestinal	949:964	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	6	theme	simulated	939:947	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	1	7	theme	microcrystalline	179:194	arg1	cellulose					196:204	microcrystalline cellulose	179:204	microcrystalline cellulose	179:204	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	4	8	theme	remarkable	587:596	arg1	stability					610:618	remarkable emulsifying stability	587:618	remarkable emulsifying stability	587:618	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
35193017	6	9	from	oxidation	990:998	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	5	10	theme	network	763:769	arg1	structure					771:779	a network structure	761:779	a network structure formed in the CC-Ca-HP emulsion	761:811	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	6	11	from	bioaccessibility	901:916	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	12	theme	oil	1147:1149	arg1	droplets					1151:1158	oil droplets	1147:1158	oil droplets	1147:1158	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	13	theme	oxidation	1022:1030	arg1	condition					1032:1040	the accelerated oxidation condition	1006:1040	the accelerated oxidation condition	1006:1040	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	14	theme	zeaxanthin	921:930	arg1	acids					884:888	free fatty acids	873:888	free fatty acids	873:888	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	14	theme	zeaxanthin	921:930	arg1	bioaccessibility					901:916	increased bioaccessibility	891:916	increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion	891:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	14	theme	zeaxanthin	921:930	arg1	oxidation					990:998	less oil oxidation	981:998	less oil oxidation	981:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	15	theme	CC-Ca-HP	828:835	arg1	emulsion					837:844	the CC-Ca-HP emulsion	824:844	the CC-Ca-HP emulsion	824:844	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	1	16	theme	cellulose	196:204	arg1	properties					165:174	the emulsifying properties	149:174	the emulsifying properties of microcrystalline cellulose	149:204	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	6	17	from	release	862:868	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	18	theme	stable	1063:1068	arg1	structure					1070:1078	the stable structure	1059:1078	the stable structure of CC-Ca-HP imparted by Ca2+-bridging	1059:1116	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	0	19	theme	emulsifying	10:20	arg1	properties					22:31	emulsifying properties	10:31	emulsifying properties of carboxylated microcrystalline cellulose	10:74	Improving emulsifying properties of carboxylated microcrystalline cellulose by calcium bridging to hydrophobic peptides.					
35193017	6	20	theme	bioaccessibility	901:916	arg1	release					862:868	a marked release	853:868	a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation	853:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	21	theme	accelerated	1010:1020	arg1	condition					1032:1040	the accelerated oxidation condition	1006:1040	the accelerated oxidation condition	1006:1040	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	5	22	theme	flow	695:698	arg1	characteristics					700:714	the steady flow characteristics	684:714	the steady flow characteristics	684:714	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	4	23	theme	composite	555:563	arg1	CC-Ca-HP					565:572	The Ca2+-bridged composite CC-Ca-HP	538:572	The Ca2+-bridged composite CC-Ca-HP	538:572	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
35193017	2	24	theme	FTIR	303:306	arg1	analysis					324:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	2	25	theme	HP	369:370	arg1	attachment					355:364	the successful attachment	340:364	the successful attachment of HP to CC	340:376	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	4	26	theme	Ca2+-bridged	542:553	arg1	CC-Ca-HP					565:572	The Ca2+-bridged composite CC-Ca-HP	538:572	The Ca2+-bridged composite CC-Ca-HP	538:572	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
35193017	5	27	theme	dynamic	720:726	arg1	properties					741:750	dynamic viscoelastic properties	720:750	dynamic viscoelastic properties	720:750	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	6	28	from	acids	884:888	arg1	digestion					966:974	the simulated gastrointestinal digestion	935:974	the simulated gastrointestinal digestion	935:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	29	theme	gastric	1198:1204	arg1	conditions					1206:1215	the harsh gastric conditions	1188:1215	the harsh gastric conditions	1188:1215	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	5	30	theme	viscoelastic	728:739	arg1	properties					741:750	dynamic viscoelastic properties	720:750	dynamic viscoelastic properties	720:750	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	6	31	theme	increased	891:899	arg1	bioaccessibility					901:916	increased bioaccessibility	891:916	increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion	891:974	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	32	theme	harsh	1192:1196	arg1	conditions					1206:1215	the harsh gastric conditions	1188:1215	the harsh gastric conditions	1188:1215	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	0	33	theme	microcrystalline	49:64	arg1	cellulose					66:74	carboxylated microcrystalline cellulose	36:74	carboxylated microcrystalline cellulose	36:74	Improving emulsifying properties of carboxylated microcrystalline cellulose by calcium bridging to hydrophobic peptides.					
35193017	6	34	theme	oxidation	990:998	arg1	release					862:868	a marked release	853:868	a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation	853:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	5	35	theme	properties	741:750	arg1	analysis					672:679	Further analysis	664:679	Further analysis of the steady flow characteristics and dynamic viscoelastic properties	664:750	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	6	36	theme	CC-Ca-HP	1083:1090	arg1	structure					1070:1078	the stable structure	1059:1078	the stable structure of CC-Ca-HP imparted by Ca2+-bridging	1059:1116	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	2	37	theme	salt	388:391	arg1	bridge					393:398	a salt bridge	386:398	a salt bridge	386:398	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	0	38	theme	carboxylated	36:47	arg1	cellulose					66:74	carboxylated microcrystalline cellulose	36:74	carboxylated microcrystalline cellulose	36:74	Improving emulsifying properties of carboxylated microcrystalline cellulose by calcium bridging to hydrophobic peptides.					
35193017	6	39	theme	oil	986:988	arg1	oxidation					990:998	less oil oxidation	981:998	less oil oxidation	981:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	40	theme	acids	884:888	arg1	release					862:868	a marked release	853:868	a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation	853:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	3	41	theme	particle	445:452	arg1	ζ-potential					508:518	ζ-potential	508:518	ζ-potential	508:518	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	41	theme	particle	445:452	arg1	characteristics					454:468	the particle characteristics	441:468	the particle characteristics	441:468	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	41	theme	particle	445:452	arg1	wettability					525:535	wettability	525:535	wettability	525:535	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	41	theme	particle	445:452	arg1	size					502:505	particle size	493:505	particle size	493:505	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	5	42	theme	steady	688:693	arg1	characteristics					700:714	the steady flow characteristics	684:714	the steady flow characteristics	684:714	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	6	43	theme	fatty	878:882	arg1	acids					884:888	free fatty acids	873:888	free fatty acids	873:888	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	0	44	theme	cellulose	66:74	arg1	properties					22:31	emulsifying properties	10:31	emulsifying properties of carboxylated microcrystalline cellulose	10:74	Improving emulsifying properties of carboxylated microcrystalline cellulose by calcium bridging to hydrophobic peptides.					
35193017	3	45	theme	CC-Ca-HP	473:480	arg1	ζ-potential					508:518	ζ-potential	508:518	ζ-potential	508:518	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	45	theme	CC-Ca-HP	473:480	arg1	characteristics					454:468	the particle characteristics	441:468	the particle characteristics	441:468	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	45	theme	CC-Ca-HP	473:480	arg1	wettability					525:535	wettability	525:535	wettability	525:535	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	3	45	theme	CC-Ca-HP	473:480	arg1	size					502:505	particle size	493:505	particle size	493:505	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	6	46	theme	free	873:876	arg1	acids					884:888	free fatty acids	873:888	free fatty acids	873:888	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	3	47	theme	particle	493:500	arg1	size					502:505	particle size	493:505	particle size	493:505	The Ca2+-bridging significantly changed the particle characteristics of CC-Ca-HP, including particle size, ζ-potential, and wettability.					
35193017	5	48	theme	characteristics	700:714	arg1	analysis					672:679	Further analysis	664:679	Further analysis of the steady flow characteristics and dynamic viscoelastic properties	664:750	Further analysis of the steady flow characteristics and dynamic viscoelastic properties revealed a network structure formed in the CC-Ca-HP emulsion.					
35193017	2	49	theme	spectra	316:322	arg1	analysis					324:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	2	50	theme	XRD	312:314	arg1	analysis					324:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis	303:331	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	1	51	theme	hydrophobic	244:254	arg1	peptides					268:275	hydrophobic oat globule peptides	244:275	hydrophobic oat globule peptides	244:275	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	6	52	theme	marked	855:860	arg1	release					862:868	a marked release	853:868	a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation	853:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	1	53	theme	emulsifying	153:163	arg1	properties					165:174	the emulsifying properties	149:174	the emulsifying properties of microcrystalline cellulose	149:204	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	1	54	theme	oat	256:258	arg1	peptides					268:275	hydrophobic oat globule peptides	244:275	hydrophobic oat globule peptides	244:275	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	2	55	attach	attachment	355:364	arg1	CC					375:376	CC	375:376	CC	375:376	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	2	55	attach	attachment	355:364	arg2	HP					369:370	HP	369:370	HP	369:370	FTIR and XRD spectra analysis proved the successful attachment of HP to CC through a salt bridge.					
35193017	1	56	theme	globule	260:266	arg1	peptides					268:275	hydrophobic oat globule peptides	244:275	hydrophobic oat globule peptides	244:275	This study aimed to improve the emulsifying properties of microcrystalline cellulose by carboxylating (CC) and bridging to hydrophobic oat globule peptides (HP) via Ca2+ (CC-Ca-HP).					
35193017	6	57	theme	droplets	1151:1158	arg1	aggregation					1132:1142	the aggregation	1128:1142	the aggregation of oil droplets	1128:1158	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	6	58	from	digestion	966:974	arg1	release					862:868	a marked release	853:868	a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation	853:998	Moreover, the CC-Ca-HP emulsion showed a marked release of free fatty acids, increased bioaccessibility of zeaxanthin in the simulated gastrointestinal digestion, and less oil oxidation under the accelerated oxidation condition, indicating that the stable structure of CC-Ca-HP imparted by Ca2+-bridging prevented the aggregation of oil droplets as collision occurred under the harsh gastric conditions.					
35193017	4	59	theme	nonbridged	638:647	arg1	CC-HP					656:660	CC-HP	656:660	CC-HP	656:660	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
35193017	4	59	theme	nonbridged	638:647	arg1	blend					649:653	the nonbridged blend	634:653	the nonbridged blend (CC-HP)	634:661	The Ca2+-bridged composite CC-Ca-HP demonstrated remarkable emulsifying stability compared with the nonbridged blend (CC-HP).					
36184142	0	0	theme	regeneration	105:116	arg1	regulation					86:95	sequential regulation	75:95	sequential regulation of bone regeneration	75:116	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	2	1	theme	osteogenic	584:593	arg1	protein					614:620	osteogenic bone morphogenetic protein 2	584:622	osteogenic bone morphogenetic protein 2 (BMP-2)	584:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	1	theme	osteogenic	584:593	arg1	BMP-2					625:629	BMP-2	625:629	BMP-2	625:629	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	4	2	theme	hydrogel	815:822	arg1	composite					824:832	the hydrogel composite	811:832	the hydrogel composite	811:832	Then, the hydrogel composite allows NIR-light-responsive release of BMP-2, which maximizes its osteoinductive effects.					
36184142	1	3	theme	main	183:186	arg1	osteogenesis					158:169	poor osteogenesis	153:169	poor osteogenesis	153:169	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	3	theme	main	183:186	arg1	reaction					140:147	inflammatory reaction	127:147	inflammatory reaction	127:147	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	3	theme	main	183:186	arg1	causes					188:193	the two main causes	175:193	the two main causes of failure for bone-defect healing	175:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	0	4	theme	bone	100:103	arg1	regeneration					105:116	bone regeneration	100:116	bone regeneration	100:116	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	2	5	theme	magnesium-calcium	397:413	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	6	dep	drug	567:570	arg1	BMP-2					625:629	BMP-2	625:629	BMP-2	625:629	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	6	dep	drug	567:570	arg1	protein					614:620	osteogenic bone morphogenetic protein 2	584:622	osteogenic bone morphogenetic protein 2 (BMP-2)	584:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	6	dep	drug	567:570	arg1	aspirin					572:578	aspirin	572:578	aspirin	572:578	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	7	theme	carbonate	415:423	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	4	8	theme	NIR-light-responsive	841:860	arg1	release					862:868	NIR-light-responsive release	841:868	NIR-light-responsive release	841:868	Then, the hydrogel composite allows NIR-light-responsive release of BMP-2, which maximizes its osteoinductive effects.					
36184142	2	9	theme	thermo-responsive	462:478	arg1	hydrogel					502:509	a thermo-responsive hydroxybutyl chitosan hydrogel	460:509	a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	460:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	6	10	theme	alternative	1121:1131	arg1	strategy					1133:1140	an efficient alternative strategy	1108:1140	an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering	1108:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	4	11	theme	osteoinductive	900:913	arg1	effects					915:921	its osteoinductive effects	896:921	its osteoinductive effects	896:921	Then, the hydrogel composite allows NIR-light-responsive release of BMP-2, which maximizes its osteoinductive effects.					
36184142	1	12	theme	failure	198:204	arg1	osteogenesis					158:169	poor osteogenesis	153:169	poor osteogenesis	153:169	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	12	theme	failure	198:204	arg1	reaction					140:147	inflammatory reaction	127:147	inflammatory reaction	127:147	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	12	theme	failure	198:204	arg1	causes					188:193	the two main causes	175:193	the two main causes of failure for bone-defect healing	175:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	0	13	theme	dual-responsive	2:16	arg1	hydrogel					62:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel	0:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.	0:117	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	2	14	theme	near-infrared	340:352	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	4	15	theme	BMP-2	873:877	arg1	release					862:868	NIR-light-responsive release	841:868	NIR-light-responsive release	841:868	Then, the hydrogel composite allows NIR-light-responsive release of BMP-2, which maximizes its osteoinductive effects.					
36184142	5	16	theme	new-bone	1055:1062	arg1	formation					1064:1072	new-bone formation	1055:1072	new-bone formation	1055:1072	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	5	17	theme	calvaria-defect	940:954	arg1	model					956:960	an SD rat calvaria-defect model	930:960	an SD rat calvaria-defect model	930:960	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	6	18	theme	efficient	1111:1119	arg1	strategy					1133:1140	an efficient alternative strategy	1108:1140	an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering	1108:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	1	19	theme	Delayed	119:125	arg1	osteogenesis					158:169	poor osteogenesis	153:169	poor osteogenesis	153:169	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	19	theme	Delayed	119:125	arg1	causes					188:193	the two main causes	175:193	the two main causes of failure for bone-defect healing	175:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	19	theme	Delayed	119:125	arg1	reaction					140:147	inflammatory reaction	127:147	inflammatory reaction	127:147	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	20	theme	bone-defect	210:220	arg1	healing					222:228	bone-defect healing	210:228	bone-defect healing	210:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	0	21	theme	hydroxybutyl	40:51	arg1	hydrogel					62:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel	0:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.	0:117	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	1	22	theme	inflammatory	127:138	arg1	osteogenesis					158:169	poor osteogenesis	153:169	poor osteogenesis	153:169	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	22	theme	inflammatory	127:138	arg1	causes					188:193	the two main causes	175:193	the two main causes of failure for bone-defect healing	175:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	22	theme	inflammatory	127:138	arg1	reaction					140:147	inflammatory reaction	127:147	inflammatory reaction	127:147	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	0	23	theme	polydopamine-modified	18:38	arg1	hydrogel					62:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel	0:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.	0:117	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	2	24	theme	anti-inflammatory	549:565	arg1	drug					567:570	the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	545:630	the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	545:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	5	25	theme	sequential	967:976	arg1	release					995:1001	the sequential and controllable release	963:1001	the sequential and controllable release achieved by the hydrogel	963:1026	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	2	26	theme	-light-responsive	359:375	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	6	27	theme	tissue	1207:1212	arg1	engineering					1214:1224	bone tissue engineering	1202:1224	bone tissue engineering	1202:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	2	28	theme	chitosan	493:500	arg1	hydrogel					502:509	a thermo-responsive hydroxybutyl chitosan hydrogel	460:509	a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	460:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	29	theme	drug	567:570	arg1	delivery					533:540	sequential delivery	522:540	sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	522:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	6	30	theme	current	1085:1091	arg1	study					1093:1097	the current study	1081:1097	the current study	1081:1097	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	0	31	theme	chitosan	53:60	arg1	hydrogel					62:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel	0:69	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.	0:117	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	2	32	theme	sequential	522:531	arg1	delivery					533:540	sequential delivery	522:540	sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	522:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	5	33	theme	controllable	982:993	arg1	release					995:1001	the sequential and controllable release	963:1001	the sequential and controllable release achieved by the hydrogel	963:1026	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	2	34	theme	hydroxybutyl	480:491	arg1	hydrogel					502:509	a thermo-responsive hydroxybutyl chitosan hydrogel	460:509	a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2)	460:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	0	35	theme	sequential	75:84	arg1	regulation					86:95	sequential regulation	75:95	sequential regulation of bone regeneration	75:116	A dual-responsive polydopamine-modified hydroxybutyl chitosan hydrogel for sequential regulation of bone regeneration.					
36184142	6	36	theme	bone	1202:1205	arg1	engineering					1214:1224	bone tissue engineering	1202:1224	bone tissue engineering	1202:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	2	37	theme	polydopamine-coated	377:395	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	5	38	theme	SD	933:934	arg1	model					956:960	an SD rat calvaria-defect model	930:960	an SD rat calvaria-defect model	930:960	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	3	39	theme	hydrogel	677:684	arg1	composite					686:694	the hydrogel composite	673:694	the hydrogel composite	673:694	By initially releasing aspirin rapidly, the hydrogel composite efficiently ameliorates early-stage inflammatory reaction and promotes transition to the regenerative phase.					
36184142	1	40	theme	poor	153:156	arg1	osteogenesis					158:169	poor osteogenesis	153:169	poor osteogenesis	153:169	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	40	theme	poor	153:156	arg1	reaction					140:147	inflammatory reaction	127:147	inflammatory reaction	127:147	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	1	40	theme	poor	153:156	arg1	causes					188:193	the two main causes	175:193	the two main causes of failure for bone-defect healing	175:228	Delayed inflammatory reaction and poor osteogenesis are the two main causes of failure for bone-defect healing.					
36184142	3	41	theme	inflammatory	732:743	arg1	reaction					745:752	early-stage inflammatory reaction	720:752	early-stage inflammatory reaction	720:752	By initially releasing aspirin rapidly, the hydrogel composite efficiently ameliorates early-stage inflammatory reaction and promotes transition to the regenerative phase.					
36184142	2	42	theme	hydrogel	284:291	arg1	composite					293:301	a dual-responsive hydrogel composite	266:301	a dual-responsive hydrogel composite	266:301	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	43	theme	present	251:257	arg1	study					259:263	the present study	247:263	the present study	247:263	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	44	theme	dual-responsive	268:282	arg1	composite					293:301	a dual-responsive hydrogel composite	266:301	a dual-responsive hydrogel composite	266:301	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	45	theme	NIR	355:357	arg1	microspheres					425:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres	340:436	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	46	theme	morphogenetic	600:612	arg1	protein					614:620	osteogenic bone morphogenetic protein 2	584:622	osteogenic bone morphogenetic protein 2 (BMP-2)	584:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	46	theme	morphogenetic	600:612	arg1	BMP-2					625:629	BMP-2	625:629	BMP-2	625:629	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	3	47	theme	regenerative	785:796	arg1	phase					798:802	the regenerative phase	781:802	the regenerative phase	781:802	By initially releasing aspirin rapidly, the hydrogel composite efficiently ameliorates early-stage inflammatory reaction and promotes transition to the regenerative phase.					
36184142	6	48	theme	therapeutic	1173:1183	arg1	biomaterials					1185:1196	multifunctional therapeutic biomaterials	1157:1196	multifunctional therapeutic biomaterials for bone tissue engineering	1157:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36184142	2	49	theme	bone	595:598	arg1	protein					614:620	osteogenic bone morphogenetic protein 2	584:622	osteogenic bone morphogenetic protein 2 (BMP-2)	584:630	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	2	49	theme	bone	595:598	arg1	BMP-2					625:629	BMP-2	625:629	BMP-2	625:629	Accordingly, in the present study, a dual-responsive hydrogel composite was successfully fabricated in which near-infrared (NIR)-light-responsive polydopamine-coated magnesium-calcium carbonate microspheres are incorporated into a thermo-responsive hydroxybutyl chitosan hydrogel to provide sequential delivery of the anti-inflammatory drug aspirin and osteogenic bone morphogenetic protein 2 (BMP-2).					
36184142	3	50	theme	early-stage	720:730	arg1	reaction					745:752	early-stage inflammatory reaction	720:752	early-stage inflammatory reaction	720:752	By initially releasing aspirin rapidly, the hydrogel composite efficiently ameliorates early-stage inflammatory reaction and promotes transition to the regenerative phase.					
36184142	5	51	theme	rat	936:938	arg1	model					956:960	an SD rat calvaria-defect model	930:960	an SD rat calvaria-defect model	930:960	Using an SD rat calvaria-defect model, the sequential and controllable release achieved by the hydrogel is demonstrated to promote new-bone formation.					
36184142	6	52	theme	multifunctional	1157:1171	arg1	biomaterials					1185:1196	multifunctional therapeutic biomaterials	1157:1196	multifunctional therapeutic biomaterials for bone tissue engineering	1157:1224	Thus, the current study provides an efficient alternative strategy for developing multifunctional therapeutic biomaterials for bone tissue engineering.					
36330858	0	0	theme	tea	99:101	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	5	1	with	GTE	978:980	arg1	pH					989:990	a pH	987:990	a pH of 7.4	987:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	3	2	theme	composite	684:692	arg1	particles					694:702	CS-Gel-GTE composite particles	673:702	CS-Gel-GTE composite particles	673:702	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	0	3	theme	chitosan-gelatin-green	76:97	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	6	4	theme	composite	1055:1063	arg1	particles					1065:1073	the composite particles	1051:1073	the composite particles	1051:1073	A cellular study was also performed to investigate the composite particles' cell viability and neuroprotective effects.					
36330858	0	5	theme	composite	111:119	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	8	6	theme	protein	1404:1410	arg1	expression					1412:1421	α-syn protein expression	1398:1421	α-syn protein expression	1398:1421	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	0	7	theme	extract	103:109	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	8	8	theme	α-syn	1398:1402	arg1	expression					1412:1421	α-syn protein expression	1398:1421	α-syn protein expression	1398:1421	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	5	9	theme	7.4	995:997	arg1	pH					989:990	a pH	987:990	a pH of 7.4	987:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	2	10	theme	excellent	547:555	arg1	properties					569:578	excellent antioxidant properties	547:578	excellent antioxidant properties for therapeutic purposes in PD	547:609	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	4	11	theme	various	794:800	arg1	methods					819:825	various characterization methods	794:825	various characterization methods	794:825	The composite particles were investigated using various characterization methods.					
36330858	7	12	from	viability	1153:1161	arg1	apoptosis					1199:1207	cell apoptosis	1194:1207	cell apoptosis	1194:1207	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	5	13	theme	release	948:954	arg1	time					956:959	a prolonged release time	936:959	a prolonged release time of nine days for GTE with a pH of 7.4	936:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	0	14	theme	particles	121:129	arg1	fabrication					32:42	fabrication	32:42	fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	32:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	1	15	theme	minor	385:389	arg1	effects					396:402	minor side effects	385:402	minor side effects	385:402	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	7	16	theme	significant	1169:1179	arg1	reduction					1181:1189	a significant reduction	1167:1189	a significant reduction in cell apoptosis	1167:1207	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	7	17	theme	cell	1148:1151	arg1	viability					1153:1161	enhanced cell viability	1139:1161	enhanced cell viability	1139:1161	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	8	18	theme	oxygen	1310:1315	arg1	ROS					1326:1328	ROS	1326:1328	ROS	1326:1328	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	8	18	theme	oxygen	1310:1315	arg1	species					1317:1323	reactive oxygen species	1301:1323	reactive oxygen species (ROS)	1301:1329	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	0	19	theme	green	2:6	arg1	approach					19:26	A green and facile approach	0:26	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	0:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	1	20	theme	side	391:394	arg1	effects					396:402	minor side effects	385:402	minor side effects	385:402	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	5	21	with	particles	921:929	arg1	time					956:959	a prolonged release time	936:959	a prolonged release time of nine days for GTE with a pH of 7.4	936:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	0	22	with	particles	121:129	arg1	effects					173:179	neuroprotective and Neurotherapeutic effects	136:179	neuroprotective and Neurotherapeutic effects	136:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	2	23	theme	chitosan-gelatin-green	458:479	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	1	24	theme	disease	302:308	arg1	treatment					277:285	the treatment	273:285	the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects	273:402	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	8	25	theme	species	1317:1323	arg1	formation					1288:1296	the formation	1284:1296	the formation of reactive oxygen species (ROS)	1284:1329	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	3	26	theme	innovative	615:624	arg1	system					655:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	0	27	theme	facile	12:17	arg1	approach					19:26	A green and facile approach	0:26	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	0:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	7	28	theme	cell	1194:1197	arg1	apoptosis					1199:1207	cell apoptosis	1194:1207	cell apoptosis	1194:1207	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	8	29	theme	enzyme	1367:1372	arg1	expression					1374:1383	tyrosine hydroxylase (TH) enzyme expression	1341:1383	tyrosine hydroxylase (TH) enzyme expression	1341:1383	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	2	30	theme	biocompatible	426:438	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	0	31	theme	neuroprotective	136:150	arg1	effects					173:179	neuroprotective and Neurotherapeutic effects	136:179	neuroprotective and Neurotherapeutic effects	136:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	9	32	theme	PD	1486:1487	arg1	treatment					1489:1497	PD treatment	1486:1497	PD treatment	1486:1497	Overall, this study offers exquisite natural biomaterials for PD treatment.					
36330858	6	33	theme	neuroprotective	1095:1109	arg1	effects					1111:1117	neuroprotective effects	1095:1117	neuroprotective effects	1095:1117	A cellular study was also performed to investigate the composite particles' cell viability and neuroprotective effects.					
36330858	2	34	theme	novel	420:424	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	2	35	theme	therapeutic	584:594	arg1	purposes					596:603	therapeutic purposes	584:603	therapeutic purposes in PD	584:609	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	8	36	theme	tyrosine	1341:1348	arg1	TH					1363:1364	TH	1363:1364	TH	1363:1364	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	8	36	theme	tyrosine	1341:1348	arg1	hydroxylase					1350:1360	tyrosine hydroxylase	1341:1360	tyrosine hydroxylase (TH) enzyme expression	1341:1383	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	1	37	dep	design	207:212	arg1	The					203:205	The	203:205	The	203:205	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	2	38	theme	composite	506:514	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	1	39	theme	bio-inspired	233:244	arg1	materials					246:254	bio-inspired materials	233:254	bio-inspired materials	233:254	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	2	40	theme	CS-Gel-GTE	494:503	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	7	41	from	reduction	1181:1189	arg1	apoptosis					1199:1207	cell apoptosis	1194:1207	cell apoptosis	1194:1207	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	0	42	theme	Neurotherapeutic	156:171	arg1	effects					173:179	neuroprotective and Neurotherapeutic effects	136:179	neuroprotective and Neurotherapeutic effects	136:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	3	43	theme	only	707:710	arg1	1 min					712:716	only 1 min	707:716	only 1 min using a single-step method	707:743	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	2	44	theme	biodegradable	444:456	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	1	45	theme	materials	246:254	arg1	design					207:212	design	207:212	design	207:212	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	1	45	theme	materials	246:254	arg1	fabrication					218:228	fabrication	218:228	fabrication	218:228	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	8	46	theme	reactive	1301:1308	arg1	ROS					1326:1328	ROS	1326:1328	ROS	1326:1328	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	8	46	theme	reactive	1301:1308	arg1	species					1317:1323	reactive oxygen species	1301:1323	reactive oxygen species (ROS)	1301:1329	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	6	47	theme	cellular	1002:1009	arg1	study					1011:1015	A cellular study	1000:1015	A cellular study	1000:1015	A cellular study was also performed to investigate the composite particles' cell viability and neuroprotective effects.					
36330858	0	48	theme	In	182:183	arg1	evaluation					191:200	In vitro evaluation	182:200	In vitro evaluation	182:200	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	3	49	theme	angle-dependent	626:640	arg1	system					655:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	0	50	dep	evaluation	191:200	arg1	approach					19:26	A green and facile approach	0:26	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	0:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	2	51	theme	extract	485:491	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	7	52	theme	enhanced	1139:1146	arg1	viability					1153:1161	enhanced cell viability	1139:1161	enhanced cell viability	1139:1161	The results showed enhanced cell viability and a significant reduction in cell apoptosis.					
36330858	3	53	theme	electrospray	642:653	arg1	system					655:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system	612:660	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	8	54	theme	hydroxylase	1350:1360	arg1	expression					1374:1383	tyrosine hydroxylase (TH) enzyme expression	1341:1383	tyrosine hydroxylase (TH) enzyme expression	1341:1383	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	5	55	dep	facile	849:854	arg1	addition					831:838	addition	831:838	addition	831:838	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	1	56	theme	remarkable	328:337	arg1	properties					351:360	their remarkable antioxidant properties	322:360	their remarkable antioxidant properties	322:360	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	4	57	theme	composite	750:758	arg1	particles					760:768	The composite particles	746:768	The composite particles	746:768	The composite particles were investigated using various characterization methods.					
36330858	0	58	dep	In	182:183	arg1	vitro					185:189	vitro	185:189	vitro	185:189	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	8	59	theme	synthesized	1227:1237	arg1	biomaterials					1239:1250	the synthesized biomaterials	1223:1250	the synthesized biomaterials	1223:1250	In addition, the synthesized biomaterials showed the potential to inhibit the formation of reactive oxygen species (ROS), increase tyrosine hydroxylase (TH) enzyme expression and decrease α-syn protein expression.					
36330858	3	60	theme	single-step	726:736	arg1	method					738:743	a single-step method	724:743	a single-step method	724:743	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	9	61	theme	natural	1461:1467	arg1	biomaterials					1469:1480	exquisite natural biomaterials	1451:1480	exquisite natural biomaterials for PD treatment	1451:1497	Overall, this study offers exquisite natural biomaterials for PD treatment.					
36330858	4	62	theme	characterization	802:817	arg1	methods					819:825	various characterization methods	794:825	various characterization methods	794:825	The composite particles were investigated using various characterization methods.					
36330858	9	63	theme	exquisite	1451:1459	arg1	biomaterials					1469:1480	exquisite natural biomaterials	1451:1480	exquisite natural biomaterials for PD treatment	1451:1497	Overall, this study offers exquisite natural biomaterials for PD treatment.					
36330858	0	64	theme	anti-Parkinson	61:74	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	5	65	theme	prolonged	938:946	arg1	time					956:959	a prolonged release time	936:959	a prolonged release time of nine days for GTE with a pH of 7.4	936:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	3	66	theme	CS-Gel-GTE	673:682	arg1	particles					694:702	CS-Gel-GTE composite particles	673:702	CS-Gel-GTE composite particles	673:702	An innovative angle-dependent electrospray system fabricated CS-Gel-GTE composite particles in only 1 min using a single-step method.					
36330858	5	67	theme	particles	921:929	arg1	formation					908:916	the formation	904:916	the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4	904:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	5	68	theme	days	969:972	arg1	time					956:959	a prolonged release time	936:959	a prolonged release time of nine days for GTE with a pH of 7.4	936:997	In addition to being facile and cost-effective, our methodology resulted in the formation of particles with a prolonged release time of nine days for GTE with a pH of 7.4.					
36330858	6	69	theme	cell	1076:1079	arg1	viability					1081:1089	cell viability	1076:1089	cell viability	1076:1089	A cellular study was also performed to investigate the composite particles' cell viability and neuroprotective effects.					
36330858	0	70	theme	biocompatible	47:59	arg1	particles					121:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles	47:129	biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects	47:179	A green and facile approach for fabrication of biocompatible anti-Parkinson chitosan-gelatin-green tea extract composite particles with neuroprotective and Neurotherapeutic effects: In vitro evaluation.					
36330858	1	71	theme	antioxidant	339:349	arg1	properties					351:360	their remarkable antioxidant properties	322:360	their remarkable antioxidant properties	322:360	The design and fabrication of bio-inspired materials are valuable for the treatment of Parkinson's disease (PD) due to their remarkable antioxidant properties, biocompatibility, and minor side effects.					
36330858	2	72	from	purposes	596:603	arg1	PD					608:609	PD	608:609	PD	608:609	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	2	73	theme	tea	481:483	arg1	particles					516:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles	420:524	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36330858	2	74	theme	antioxidant	557:567	arg1	properties					569:578	excellent antioxidant properties	547:578	excellent antioxidant properties for therapeutic purposes in PD	547:609	In this study, novel biocompatible and biodegradable chitosan-gelatin-green tea extract (CS-Gel-GTE) composite particles were fabricated with excellent antioxidant properties for therapeutic purposes in PD.					
36796561	0	0	theme	particulate	102:112	arg1	matter					114:119	particulate matter	102:119	particulate matter	102:119	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	5	1	theme	scanning	805:812	arg1	microscopy					823:832	scanning electron microscopy	805:832	scanning electron microscopy (SEM)	805:838	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	5	1	theme	scanning	805:812	arg1	SEM					835:837	SEM	835:837	SEM	835:837	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	1	2	theme	cellulose	159:167	arg1	CNC					183:185	CNC	183:185	CNC	183:185	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	1	2	theme	cellulose	159:167	arg1	nanocrystals					169:180	cellulose nanocrystals	159:180	cellulose nanocrystals (CNC) from sugarcane leaves (SCL)	159:214	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	7	3	theme	tensile	1033:1039	arg1	index					1041:1045	the highest tensile index	1021:1045	the highest tensile index of 3.001 MPa	1021:1058	The CNC/GO-2 recorded the highest tensile index of 3.001 MPa.					
36796561	11	4	theme	potential	1303:1311	arg1	bioresource					1313:1323	a potential bioresource	1301:1323	a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria	1301:1472	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	11	4	theme	potential	1303:1311	arg1	SCL					1294:1296	SCL	1294:1296	SCL	1294:1296	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	5	5	theme	diffraction	867:877	arg1	analysis					885:892	X-ray diffraction (XRD) analysis	861:892	X-ray diffraction (XRD) analysis of crystal lattice	861:911	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	11	6	theme	high-efficiency	1384:1398	arg1	membrane					1407:1414	high-efficiency filter membrane	1384:1414	high-efficiency filter membrane	1384:1414	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	2	7	dep	CNC	283:285	arg1	GO					322:323	GO	322:323	GO	322:323	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	9	8	theme	removal	1134:1140	arg1	efficiency					1142:1151	The highest removal efficiency	1122:1151	The highest removal efficiency of 98.08 %	1122:1162	The highest removal efficiency of 98.08 % was recorded for CNC/GO-2.					
36796561	4	9	theme	electron	585:592	arg1	microscope					594:603	transmission electron microscope	572:603	transmission electron microscope	572:603	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	0	10	theme	matter	114:119	arg1	removal					91:97	efficient removal	81:97	efficient removal of particulate matter	81:119	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	3	11	theme	steam-exploded	488:501	arg1	fibers					516:521	steam-exploded and bleached fibers	488:521	steam-exploded and bleached fibers	488:521	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	4	12	from	particles	656:664	arg1	range					673:677	the range	669:677	the range of 7.3 nm and 150 nm for diameter and length, respectively	669:736	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	13	theme	transmission	572:583	arg1	microscope					594:603	transmission electron microscope	572:603	transmission electron microscope	572:603	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	11	14	theme	filter	1400:1405	arg1	membrane					1407:1414	high-efficiency filter membrane	1384:1414	high-efficiency filter membrane	1384:1414	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	11	15	theme	particulate	1420:1430	arg1	removal					1439:1445	particulate matter removal	1420:1445	particulate matter removal	1420:1445	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	7	16	theme	3.001 MPa	1050:1058	arg1	index					1041:1045	the highest tensile index	1021:1045	the highest tensile index of 3.001 MPa	1021:1058	The CNC/GO-2 recorded the highest tensile index of 3.001 MPa.					
36796561	5	17	theme	electron	814:821	arg1	microscopy					823:832	scanning electron microscopy	805:832	scanning electron microscopy (SEM)	805:838	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	5	17	theme	electron	814:821	arg1	SEM					835:837	SEM	835:837	SEM	835:837	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	11	18	theme	matter	1432:1437	arg1	removal					1439:1445	particulate matter removal	1420:1445	particulate matter removal	1420:1445	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	5	19	theme	crystal	897:903	arg1	lattice					905:911	crystal lattice	897:911	crystal lattice	897:911	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	11	20	theme	membrane	1407:1414	arg1	nanocrystals					1352:1363	cellulose nanocrystals	1342:1363	cellulose nanocrystals	1342:1363	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	11	20	theme	membrane	1407:1414	arg1	fabrication					1369:1379	fabrication	1369:1379	fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria	1369:1472	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	3	21	theme	untreated	434:442	arg1	%					464:464	untreated SCL to 78.44 ± 0.56 %	434:464	untreated SCL to 78.44 ± 0.56 %	434:464	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	5	22	theme	membranes	776:784	arg1	Morphologies					739:750	Morphologies	739:750	Morphologies of the fiber and CNC/GO membranes	739:784	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	11	23	theme	cellulose	1342:1350	arg1	nanocrystals					1352:1363	cellulose nanocrystals	1342:1363	cellulose nanocrystals	1342:1363	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	2	24	theme	graphene	306:313	arg1	oxide					315:319	the CNC and varying amount graphene oxide	279:319	oxide	315:319	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	6	25	theme	CNC	941:943	arg1	index					932:936	The crystallinity index	914:936	The crystallinity index of CNC	914:943	The crystallinity index of CNC decreased with the addition of GO into the membranes.					
36796561	3	26	from	%	483:483	arg1	%					464:464	untreated SCL to 78.44 ± 0.56 %	434:464	untreated SCL to 78.44 ± 0.56 %	434:464	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	3	26	from	%	483:483	arg1	fibers					516:521	steam-exploded and bleached fibers	488:521	steam-exploded and bleached fibers	488:521	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	2	27	theme	amount	299:304	arg1	oxide					315:319	the CNC and varying amount graphene oxide	279:319	oxide	315:319	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	10	28	theme	sample	1286:1291	arg1	>300 CFU					1266:1273	>300 CFU	1266:1273	>300 CFU of control sample	1266:1291	CNC/GO-2 membrane reduced growth of Escherichia coli to 65 CFU compared to >300 CFU of control sample.					
36796561	2	29	theme	filtration	355:364	arg1	technique					366:374	vacuum filtration technique	348:374	vacuum filtration technique	348:374	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	0	30	theme	nanocrystal/graphene	34:53	arg1	membrane					68:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	4	31	theme	force	545:549	arg1	microscopy					551:560	Atomic force microscopy	538:560	Atomic force microscopy (AFM)	538:566	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	31	theme	force	545:549	arg1	TEM					606:608	TEM	606:608	TEM	606:608	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	31	theme	force	545:549	arg1	AFM					563:565	AFM	563:565	AFM	563:565	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	7	32	theme	highest	1025:1031	arg1	index					1041:1045	the highest tensile index	1021:1045	the highest tensile index of 3.001 MPa	1021:1058	The CNC/GO-2 recorded the highest tensile index of 3.001 MPa.					
36796561	9	33	theme	%	1162:1162	arg1	efficiency					1142:1151	The highest removal efficiency	1122:1151	The highest removal efficiency of 98.08 %	1122:1162	The highest removal efficiency of 98.08 % was recorded for CNC/GO-2.					
36796561	2	34	theme	varying	291:297	arg1	oxide					315:319	the CNC and varying amount graphene oxide	279:319	oxide	315:319	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	10	35	theme	control	1278:1284	arg1	sample					1286:1291	control sample	1278:1291	control sample	1278:1291	CNC/GO-2 membrane reduced growth of Escherichia coli to 65 CFU compared to >300 CFU of control sample.					
36796561	4	36	theme	CNC	614:616	arg1	microscopy					551:560	Atomic force microscopy	538:560	Atomic force microscopy (AFM)	538:566	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	36	theme	CNC	614:616	arg1	TEM					606:608	TEM	606:608	TEM	606:608	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	36	theme	CNC	614:616	arg1	microscope					594:603	transmission electron microscope	572:603	transmission electron microscope	572:603	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	36	theme	CNC	614:616	arg1	AFM					563:565	AFM	563:565	AFM	563:565	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	0	37	theme	cellulose	24:32	arg1	membrane					68:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	5	38	theme	lattice	905:911	arg1	analysis					885:892	X-ray diffraction (XRD) analysis	861:892	X-ray diffraction (XRD) analysis of crystal lattice	861:911	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	3	39	theme	bleached	507:514	arg1	fibers					516:521	steam-exploded and bleached fibers	488:521	steam-exploded and bleached fibers	488:521	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	0	40	theme	filter	61:66	arg1	membrane					68:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	6	41	theme	crystallinity	918:930	arg1	index					932:936	The crystallinity index	914:936	The crystallinity index of CNC	914:943	The crystallinity index of CNC decreased with the addition of GO into the membranes.					
36796561	4	42	theme	nanosized	646:654	arg1	particles					656:664	nanosized particles	646:664	nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively	646:736	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	3	43	theme	SCL	444:446	arg1	%					464:464	untreated SCL to 78.44 ± 0.56 %	434:464	untreated SCL to 78.44 ± 0.56 %	434:464	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	0	44	theme	oxide	55:59	arg1	membrane					68:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	cellulose nanocrystal/graphene oxide filter membrane	24:75	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	5	45	theme	fiber	759:763	arg1	membranes					776:784	the fiber and CNC/GO membranes	755:784	membranes	776:784	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	3	46	theme	α-cellulose	381:391	arg1	content					393:399	The α-cellulose content	377:399	The α-cellulose content	377:399	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	8	47	theme	removal	1065:1071	arg1	efficiency					1073:1082	The removal efficiency	1061:1082	The removal efficiency	1061:1082	The removal efficiency increases with increasing GO content.					
36796561	5	48	theme	CNC/GO	769:774	arg1	membranes					776:784	the fiber and CNC/GO membranes	755:784	membranes	776:784	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	4	49	theme	Atomic	538:543	arg1	microscopy					551:560	Atomic force microscopy	538:560	Atomic force microscopy (AFM)	538:566	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	49	theme	Atomic	538:543	arg1	TEM					606:608	TEM	606:608	TEM	606:608	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	49	theme	Atomic	538:543	arg1	AFM					563:565	AFM	563:565	AFM	563:565	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	8	50	dep	content	1113:1119	arg1	GO					1110:1111	GO	1110:1111	GO	1110:1111	The removal efficiency increases with increasing GO content.					
36796561	1	51	from	sugarcane	193:201	arg1	CNC					183:185	CNC	183:185	CNC	183:185	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	1	51	from	sugarcane	193:201	arg1	nanocrystals					169:180	cellulose nanocrystals	159:180	cellulose nanocrystals (CNC) from sugarcane leaves (SCL)	159:214	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	4	52	theme	7.3 nm	682:687	arg1	range					673:677	the range	669:677	the range of 7.3 nm and 150 nm for diameter and length, respectively	669:736	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	1	53	theme	study	139:143	arg1	goal					126:129	The goal	122:129	The goal of this study	122:143	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	4	54	attach	isolated	618:625	arg1	SCL					632:634	SCL	632:634	SCL	632:634	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	4	54	attach	isolated	618:625	arg2	CNC					614:616	CNC	614:616	CNC isolated from SCL	614:634	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	2	55	theme	Filter	248:253	arg1	membranes					255:263	Filter membranes	248:263	Filter membranes consisting of the CNC and varying amount graphene oxide (GO)	248:324	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	11	56	theme	fabrication	1369:1379	arg1	isolation					1329:1337	isolation	1329:1337	isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria	1329:1472	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	4	57	theme	150 nm	693:698	arg1	range					673:677	the range	669:677	the range of 7.3 nm and 150 nm for diameter and length, respectively	669:736	Atomic force microscopy (AFM) and transmission electron microscope (TEM) of CNC isolated from SCL indicated nanosized particles in the range of 7.3 nm and 150 nm for diameter and length, respectively.					
36796561	10	58	theme	CNC/GO-2	1191:1198	arg1	membrane					1200:1207	CNC/GO-2 membrane	1191:1207	CNC/GO-2 membrane	1191:1207	CNC/GO-2 membrane reduced growth of Escherichia coli to 65 CFU compared to >300 CFU of control sample.					
36796561	11	59	theme	bacteria	1465:1472	arg1	inhibition					1451:1460	inhibition	1451:1460	inhibition of bacteria	1451:1472	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	11	59	theme	bacteria	1465:1472	arg1	removal					1439:1445	particulate matter removal	1420:1445	particulate matter removal	1420:1445	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	11	60	theme	nanocrystals	1352:1363	arg1	isolation					1329:1337	isolation	1329:1337	isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria	1329:1472	SCL is a potential bioresource for isolation of cellulose nanocrystals and fabrication of high-efficiency filter membrane for particulate matter removal and inhibition of bacteria.					
36796561	1	61	dep	sugarcane	193:201	arg1	leaves					203:208	leaves	203:208	leaves	203:208	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36796561	3	62	from	%	429:429	arg1	%					464:464	untreated SCL to 78.44 ± 0.56 %	434:464	untreated SCL to 78.44 ± 0.56 %	434:464	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	3	62	from	%	429:429	arg1	fibers					516:521	steam-exploded and bleached fibers	488:521	steam-exploded and bleached fibers	488:521	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	2	63	theme	vacuum	348:353	arg1	technique					366:374	vacuum filtration technique	348:374	vacuum filtration technique	348:374	Filter membranes consisting of the CNC and varying amount graphene oxide (GO) were fabricated using vacuum filtration technique.					
36796561	6	64	theme	GO	976:977	arg1	addition					964:971	the addition	960:971	the addition of GO into the membranes	960:996	The crystallinity index of CNC decreased with the addition of GO into the membranes.					
36796561	0	65	theme	efficient	81:89	arg1	removal					91:97	efficient removal	81:97	efficient removal of particulate matter	81:119	Sugarcane leave-derived cellulose nanocrystal/graphene oxide filter membrane for efficient removal of particulate matter.					
36796561	3	66	dep	%	464:464	arg1	to					448:449	to	448:449	to	448:449	The α-cellulose content increased from 53.56 ± 0.49 % in untreated SCL to 78.44 ± 0.56 % and 84.99 ± 0.44 % in steam-exploded and bleached fibers, respectively.					
36796561	9	67	theme	highest	1126:1132	arg1	efficiency					1142:1151	The highest removal efficiency	1122:1151	The highest removal efficiency of 98.08 %	1122:1162	The highest removal efficiency of 98.08 % was recorded for CNC/GO-2.					
36796561	5	68	theme	X-ray	861:865	arg1	diffraction					867:877	X-ray diffraction	861:877	X-ray diffraction (XRD) analysis of crystal lattice	861:911	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	5	68	theme	X-ray	861:865	arg1	XRD					880:882	XRD	880:882	XRD	880:882	Morphologies of the fiber and CNC/GO membranes were determined by scanning electron microscopy (SEM) and crystallinity by X-ray diffraction (XRD) analysis of crystal lattice.					
36796561	10	69	theme	coli	1239:1242	arg1	growth					1217:1222	growth	1217:1222	growth of Escherichia coli	1217:1242	CNC/GO-2 membrane reduced growth of Escherichia coli to 65 CFU compared to >300 CFU of control sample.					
36796561	1	70	theme	filter	230:235	arg1	membranes					237:245	filter membranes	230:245	filter membranes	230:245	The goal of this study is to isolate cellulose nanocrystals (CNC) from sugarcane leaves (SCL) and fabricate filter membranes.					
36328271	0	0	theme	silk	84:87	arg1	fibroin					89:95	silk fibroin	84:95	silk fibroin with biological activity and hyperthermia application	84:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	1	1	theme	current	159:165	arg1	study					167:171	the current study	155:171	the current study	155:171	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	7	2	theme	nanocomposite	1141:1153	arg1	behavior					1105:1112	the hyperthermia behavior	1088:1112	the hyperthermia behavior of the fabricated magnetic nanocomposite	1088:1153	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	8	3	theme	future	1306:1311	arg1	studies					1313:1319	future studies	1306:1319	future studies	1306:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	8	4	theme	proposed	1228:1235	arg1	nanocomposite					1237:1249	The proposed nanocomposite	1224:1249	The proposed nanocomposite	1224:1249	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	8	4	theme	proposed	1228:1235	arg1	candidate					1261:1269	a good candidate	1254:1269	a good candidate for wound dressing applications in future studies	1254:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	5	5	theme	red	866:868	arg1	RBCs					883:886	RBCs	883:886	RBCs	883:886	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	5	5	theme	red	866:868	arg1	cells					876:880	red blood cells	866:880	red blood cells (RBCs)	866:887	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	3	6	from	usage	465:469	arg1	applications					518:529	hyperthermia applications	505:529	hyperthermia applications	505:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	7	7	theme	hyperthermia	1092:1103	arg1	behavior					1105:1112	the hyperthermia behavior	1088:1112	the hyperthermia behavior of the fabricated magnetic nanocomposite	1088:1153	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	1	8	theme	nanocomposite	297:309	arg1	scaffold					311:318	a nanocomposite scaffold	295:318	a nanocomposite scaffold	295:318	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	6	9	theme	nanocomposite	1064:1076	arg1	cytotoxicity					1023:1034	the cytotoxicity	1019:1034	the cytotoxicity of the synthesized magnetic nanocomposite	1019:1076	Furthermore, an MTT assay was utilized to assess the cytotoxicity of the synthesized magnetic nanocomposite.					
36328271	0	10	with	embedded	70:77	arg1	fibroin					89:95	silk fibroin	84:95	silk fibroin with biological activity and hyperthermia application	84:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	5	11	theme	blood	870:874	arg1	RBCs					883:886	RBCs	883:886	RBCs	883:886	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	5	11	theme	blood	870:874	arg1	cells					876:880	red blood cells	866:880	red blood cells (RBCs)	866:887	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	4	12	theme	thermogravimetric	643:659	arg1	TGA					671:673	TGA	671:673	TGA	671:673	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	12	theme	thermogravimetric	643:659	arg1	analysis					661:668	thermogravimetric analysis	643:668	thermogravimetric analysis (TGA)	643:674	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	12	theme	thermogravimetric	643:659	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	13	theme	sample	757:762	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	13	theme	sample	757:762	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	13	theme	sample	757:762	arg1	VSM					778:780	VSM	778:780	VSM	778:780	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	5	14	theme	cells	876:880	arg1	%					861:861	about 100 %	851:861	about 100 % of red blood cells (RBCs)	851:887	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	5	14	theme	cells	876:880	arg1	RBCs					883:886	RBCs	883:886	RBCs	883:886	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	5	14	theme	cells	876:880	arg1	cells					876:880	red blood cells	866:880	red blood cells (RBCs)	866:887	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	8	15	from	applications	1290:1301	arg1	studies					1313:1319	future studies	1306:1319	future studies	1306:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	2	16	theme	silk	342:345	arg1	SF					356:357	SF	356:357	SF	356:357	With the addition of silk fibroin (SF), the strength of the synthesized composite was increased.					
36328271	2	16	theme	silk	342:345	arg1	fibroin					347:353	silk fibroin	342:353	silk fibroin (SF)	342:358	With the addition of silk fibroin (SF), the strength of the synthesized composite was increased.					
36328271	0	17	theme	biological	102:111	arg1	activity					113:120	biological activity	102:120	biological activity	102:120	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	4	18	theme	Vibrating-	746:755	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	18	theme	Vibrating-	746:755	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	18	theme	Vibrating-	746:755	arg1	VSM					778:780	VSM	778:780	VSM	778:780	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	6	19	theme	synthesized	1043:1053	arg1	nanocomposite					1064:1076	the synthesized magnetic nanocomposite	1039:1076	the synthesized magnetic nanocomposite	1039:1076	Furthermore, an MTT assay was utilized to assess the cytotoxicity of the synthesized magnetic nanocomposite.					
36328271	1	20	theme	sodium	174:179	arg1	alginate					181:188	sodium alginate	174:188	sodium alginate (SA)	174:193	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	1	20	theme	sodium	174:179	arg1	SA					191:192	SA	191:192	SA	191:192	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	0	21	theme	novel	2:6	arg1	nanocomposite					17:29	A novel magnetic nanocomposite	0:29	A novel magnetic nanocomposite	0:29	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	4	22	theme	field	589:593	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	22	theme	field	589:593	arg1	analysis					661:668	thermogravimetric analysis	643:668	thermogravimetric analysis (TGA)	643:674	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	22	theme	field	589:593	arg1	infrared					697:704	infrared	697:704	infrared	697:704	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	22	theme	field	589:593	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	22	theme	field	589:593	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	22	theme	field	589:593	arg1	FE-SEM					634:639	FE-SEM	634:639	FE-SEM	634:639	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	3	23	theme	magnetic	479:486	arg1	nanocomposite					488:500	this magnetic nanocomposite	474:500	this magnetic nanocomposite in hyperthermia applications	474:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	4	24	theme	electron	613:620	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	24	theme	electron	613:620	arg1	analysis					661:668	thermogravimetric analysis	643:668	thermogravimetric analysis (TGA)	643:674	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	24	theme	electron	613:620	arg1	infrared					697:704	infrared	697:704	infrared	697:704	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	24	theme	electron	613:620	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	24	theme	electron	613:620	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	24	theme	electron	613:620	arg1	FE-SEM					634:639	FE-SEM	634:639	FE-SEM	634:639	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	7	25	theme	specific	1178:1185	arg1	73.53 W/g					1213:1221	73.53 W/g	1213:1221	73.53 W/g	1213:1221	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	7	25	theme	specific	1178:1185	arg1	rate					1198:1201	the specific absorption rate	1174:1201	the specific absorption rate (SAR)	1174:1207	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	4	26	theme	emission	595:602	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	26	theme	emission	595:602	arg1	analysis					661:668	thermogravimetric analysis	643:668	thermogravimetric analysis (TGA)	643:674	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	26	theme	emission	595:602	arg1	infrared					697:704	infrared	697:704	infrared	697:704	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	26	theme	emission	595:602	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	26	theme	emission	595:602	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	26	theme	emission	595:602	arg1	FE-SEM					634:639	FE-SEM	634:639	FE-SEM	634:639	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	3	27	theme	nanocomposite	488:500	arg1	usage					465:469	the usage	461:469	the usage of this magnetic nanocomposite in hyperthermia applications	461:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	4	28	theme	scanning	604:611	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	28	theme	scanning	604:611	arg1	analysis					661:668	thermogravimetric analysis	643:668	thermogravimetric analysis (TGA)	643:674	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	28	theme	scanning	604:611	arg1	infrared					697:704	infrared	697:704	infrared	697:704	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	28	theme	scanning	604:611	arg1	magnetometer					764:775	Vibrating- sample magnetometer	746:775	Vibrating- sample magnetometer (VSM)	746:781	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	28	theme	scanning	604:611	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	28	theme	scanning	604:611	arg1	FE-SEM					634:639	FE-SEM	634:639	FE-SEM	634:639	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	1	29	theme	calcium	236:242	arg1	chloride					244:251	calcium chloride	236:251	calcium chloride	236:251	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	0	30	theme	hyperthermia	126:137	arg1	application					139:149	hyperthermia application	126:149	hyperthermia application	126:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	0	31	with	fibroin	89:95	arg1	application					139:149	hyperthermia application	126:149	hyperthermia application	126:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	0	31	with	fibroin	89:95	arg1	activity					113:120	biological activity	102:120	biological activity	102:120	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	0	32	theme	magnetic	8:15	arg1	nanocomposite					17:29	A novel magnetic nanocomposite	0:29	A novel magnetic nanocomposite	0:29	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	1	33	theme	chloride	244:251	arg1	presence					224:231	the presence	220:231	the presence of calcium chloride as a cross-linker	220:269	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	6	34	theme	magnetic	1055:1062	arg1	nanocomposite					1064:1076	the synthesized magnetic nanocomposite	1039:1076	the synthesized magnetic nanocomposite	1039:1076	Furthermore, an MTT assay was utilized to assess the cytotoxicity of the synthesized magnetic nanocomposite.					
36328271	3	35	from	applications	518:529	arg1	usage					465:469	the usage	461:469	the usage of this magnetic nanocomposite in hyperthermia applications	461:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	4	36	theme	scaffold	559:566	arg1	properties					540:549	Various properties	532:549	Various properties of this scaffold	532:566	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	5	37	theme	nanocomposite	819:831	arg1	assay					796:800	A hemolytic assay	784:800	A hemolytic assay of this magnetic nanocomposite	784:831	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	8	38	theme	dressing	1281:1288	arg1	applications					1290:1301	wound dressing applications	1275:1301	wound dressing applications in future studies	1275:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	7	39	theme	absorption	1187:1196	arg1	73.53 W/g					1213:1221	73.53 W/g	1213:1221	73.53 W/g	1213:1221	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	7	39	theme	absorption	1187:1196	arg1	rate					1198:1201	the specific absorption rate	1174:1201	the specific absorption rate (SAR)	1174:1207	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	2	40	theme	composite	393:401	arg1	strength					365:372	the strength	361:372	the strength of the synthesized composite	361:401	With the addition of silk fibroin (SF), the strength of the synthesized composite was increased.					
36328271	8	41	theme	wound	1275:1279	arg1	applications					1290:1301	wound dressing applications	1275:1301	wound dressing applications in future studies	1275:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	1	42	theme	tannic	199:204	arg1	TA					212:213	TA	212:213	TA	212:213	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	1	42	theme	tannic	199:204	arg1	acid					206:209	tannic acid	199:209	tannic acid (TA)	199:214	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	0	43	theme	acid	56:59	arg1	hydrogel					61:68	alginate-tannic acid hydrogel	40:68	alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application	40:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	8	44	theme	good	1256:1259	arg1	nanocomposite					1237:1249	The proposed nanocomposite	1224:1249	The proposed nanocomposite	1224:1249	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	8	44	theme	good	1256:1259	arg1	candidate					1261:1269	a good candidate	1254:1269	a good candidate for wound dressing applications in future studies	1254:1319	The proposed nanocomposite is a good candidate for wound dressing applications in future studies.					
36328271	7	45	theme	fabricated	1121:1130	arg1	nanocomposite					1141:1153	the fabricated magnetic nanocomposite	1117:1153	the fabricated magnetic nanocomposite	1117:1153	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	3	46	theme	Fe3O4	418:422	arg1	MNPs					448:451	MNPs	448:451	MNPs	448:451	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	3	46	theme	Fe3O4	418:422	arg1	nanoparticles					433:445	Fe3O4 magnetic nanoparticles	418:445	Fe3O4 magnetic nanoparticles (MNPs)	418:452	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	0	47	theme	alginate-tannic	40:54	arg1	hydrogel					61:68	alginate-tannic acid hydrogel	40:68	alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application	40:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	5	48	theme	2 mg/ml	920:926	arg1	concentration					903:915	a concentration	901:915	a concentration of 2 mg/ml	901:926	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	3	49	theme	hyperthermia	505:516	arg1	applications					518:529	hyperthermia applications	505:529	hyperthermia applications	505:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	3	50	theme	magnetic	424:431	arg1	MNPs					448:451	MNPs	448:451	MNPs	448:451	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	3	50	theme	magnetic	424:431	arg1	nanoparticles					433:445	Fe3O4 magnetic nanoparticles	418:445	Fe3O4 magnetic nanoparticles (MNPs)	418:452	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	1	51	used	used	277:280	arg2	acid					206:209	tannic acid	199:209	tannic acid (TA)	199:214	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	1	51	used	used	277:280	arg2	TA					212:213	TA	212:213	TA	212:213	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	1	51	used	used	277:280	arg2	SA					191:192	SA	191:192	SA	191:192	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	1	51	used	used	277:280	arg2	alginate					181:188	sodium alginate	174:188	sodium alginate (SA)	174:193	In the current study, sodium alginate (SA) and tannic acid (TA), in the presence of calcium chloride as a cross-linker, were used to fabricate a nanocomposite scaffold.					
36328271	4	52	theme	energy	715:720	arg1	EDX					740:742	EDX	740:742	EDX	740:742	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	52	theme	energy	715:720	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	52	theme	energy	715:720	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	5	53	theme	magnetic	810:817	arg1	nanocomposite					819:831	this magnetic nanocomposite	805:831	this magnetic nanocomposite	805:831	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	7	54	dep	rate	1198:1201	arg1	SAR					1204:1206	SAR	1204:1206	SAR	1204:1206	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36328271	4	55	theme	Various	532:538	arg1	properties					540:549	Various properties	532:549	Various properties of this scaffold	532:566	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	0	56	theme	embedded	70:77	arg1	hydrogel					61:68	alginate-tannic acid hydrogel	40:68	alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application	40:149	A novel magnetic nanocomposite based on alginate-tannic acid hydrogel embedded with silk fibroin with biological activity and hyperthermia application.					
36328271	2	57	theme	fibroin	347:353	arg1	addition					330:337	the addition	326:337	the addition of silk fibroin (SF)	326:358	With the addition of silk fibroin (SF), the strength of the synthesized composite was increased.					
36328271	6	58	used	utilized	1000:1007	arg2	assay					990:994	an MTT assay	983:994	an MTT assay	983:994	Furthermore, an MTT assay was utilized to assess the cytotoxicity of the synthesized magnetic nanocomposite.					
36328271	5	59	theme	hemolytic	786:794	arg1	assay					796:800	A hemolytic assay	784:800	A hemolytic assay of this magnetic nanocomposite	784:831	A hemolytic assay of this magnetic nanocomposite demonstrated that about 100 % of red blood cells (RBCs) survived at a concentration of 2 mg/ml, proving this scaffold is hemocompatible.					
36328271	3	60	from	nanocomposite	488:500	arg1	applications					518:529	hyperthermia applications	505:529	hyperthermia applications	505:529	Fe3O4 magnetic nanoparticles (MNPs) led to the usage of this magnetic nanocomposite in hyperthermia applications.					
36328271	2	61	theme	synthesized	381:391	arg1	composite					393:401	the synthesized composite	377:401	the synthesized composite	377:401	With the addition of silk fibroin (SF), the strength of the synthesized composite was increased.					
36328271	4	62	theme	dispersive	722:731	arg1	EDX					740:742	EDX	740:742	EDX	740:742	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	62	theme	dispersive	722:731	arg1	microscope					622:631	field emission scanning electron microscope	589:631	field emission scanning electron microscope (FE-SEM)	589:640	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	4	62	theme	dispersive	722:731	arg1	X-Ray					733:737	energy dispersive X-Ray	715:737	energy dispersive X-Ray (EDX)	715:743	Various properties of this scaffold were investigated by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), energy dispersive X-Ray (EDX), Vibrating- sample magnetometer (VSM).					
36328271	6	63	theme	MTT	986:988	arg1	assay					990:994	an MTT assay	983:994	an MTT assay	983:994	Furthermore, an MTT assay was utilized to assess the cytotoxicity of the synthesized magnetic nanocomposite.					
36328271	7	64	theme	magnetic	1132:1139	arg1	nanocomposite					1141:1153	the fabricated magnetic nanocomposite	1117:1153	the fabricated magnetic nanocomposite	1117:1153	Finally, the hyperthermia behavior of the fabricated magnetic nanocomposite was evaluated, and the specific absorption rate (SAR) was 73.53 W/g.					
36435461	5	0	theme	adsorption	715:724	arg1	process					726:732	a dynamic adsorption process	705:732	a dynamic adsorption process	705:732	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	8	1	theme	orange	1148:1153	arg1	solution					1121:1128	a mixed dye solution	1109:1128	a mixed dye solution of anionic methyl orange (MO) and MB	1109:1165	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	5	2	theme	PLA/PBAT-MEFB	774:786	arg1	m-2 h-1					805:811	1214 L m-2 h-1	798:811	1214 L m-2 h-1	798:811	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	5	2	theme	PLA/PBAT-MEFB	774:786	arg1	membrane					788:795	the PLA/PBAT-MEFB membrane	770:795	the PLA/PBAT-MEFB membrane (1214 L m-2 h-1)	770:812	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	6	3	theme	PLA/PBAT	916:923	arg1	membrane					925:932	the PLA/PBAT membrane	912:932	the PLA/PBAT membrane	912:932	The PLA/PBAT-MEFB membrane removed 97.2 % of MB while the PLA/PBAT membrane removed only 58.7 %.					
36435461	5	4	theme	L	846:846	arg1	membrane					832:839	the PLA/PBAT membrane	819:839	the PLA/PBAT membrane (371 L m-2 h-1)	819:855	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	5	4	theme	L	846:846	arg1	m-2 h-1					848:854	371 L m-2 h-1	842:854	371 L m-2 h-1	842:854	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	9	5	theme	separation	1345:1354	arg1	performance					1356:1366	a satisfactory separation performance	1330:1366	a satisfactory separation performance	1330:1366	Moreover, this membrane could be easily regenerated and maintained a satisfactory separation performance over several cycles.					
36435461	2	6	theme	cellulose	337:345	arg1	microfiber					347:356	functionalized cellulose microfiber	322:356	functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB)	322:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	8	7	theme	methyl	1141:1146	arg1	orange					1148:1153	anionic methyl orange	1133:1153	anionic methyl orange (MO)	1133:1158	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	8	7	theme	methyl	1141:1146	arg1	MO					1156:1157	MO	1156:1157	MO	1156:1157	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	0	8	theme	cellulose	96:104	arg1	microfiber					106:115	carboxylated cellulose microfiber	83:115	carboxylated cellulose microfiber from empty fruit bunch	83:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	7	9	from	groups	1069:1074	arg1	MEFB					1079:1082	MEFB	1079:1082	MEFB	1079:1082	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	0	10	with	polylactide	66:76	arg1	microfiber					106:115	carboxylated cellulose microfiber	83:115	carboxylated cellulose microfiber from empty fruit bunch	83:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	5	11	theme	PLA/PBAT	823:830	arg1	membrane					832:839	the PLA/PBAT membrane	819:839	the PLA/PBAT membrane (371 L m-2 h-1)	819:855	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	5	11	theme	PLA/PBAT	823:830	arg1	m-2 h-1					848:854	371 L m-2 h-1	842:854	371 L m-2 h-1	842:854	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	0	12	theme	carboxylated	83:94	arg1	microfiber					106:115	carboxylated cellulose microfiber	83:115	carboxylated cellulose microfiber from empty fruit bunch	83:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	4	13	theme	pseudo-second	542:554	arg1	order					556:560	the pseudo-second order	538:560	the pseudo-second order	538:560	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	10	14	theme	biocomposite	1468:1479	arg1	membrane					1481:1488	the proposed biocomposite membrane	1455:1488	the proposed biocomposite membrane	1455:1488	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	4	15	dep	blue	651:654	arg1	MB					657:658	MB	657:658	MB	657:658	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	9	16	theme	satisfactory	1332:1343	arg1	performance					1356:1366	a satisfactory separation performance	1330:1366	a satisfactory separation performance	1330:1366	Moreover, this membrane could be easily regenerated and maintained a satisfactory separation performance over several cycles.					
36435461	5	17	theme	L	803:803	arg1	m-2 h-1					805:811	1214 L m-2 h-1	798:811	1214 L m-2 h-1	798:811	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	5	17	theme	L	803:803	arg1	membrane					788:795	the PLA/PBAT-MEFB membrane	770:795	the PLA/PBAT-MEFB membrane (1214 L m-2 h-1)	770:812	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	6	18	theme	MB	903:904	arg1	MB					903:904	MB	903:904	MB	903:904	The PLA/PBAT-MEFB membrane removed 97.2 % of MB while the PLA/PBAT membrane removed only 58.7 %.					
36435461	6	18	theme	MB	903:904	arg1	%					898:898	97.2 %	893:898	97.2 % of MB	893:904	The PLA/PBAT-MEFB membrane removed 97.2 % of MB while the PLA/PBAT membrane removed only 58.7 %.					
36435461	7	19	theme	carboxyl	1060:1067	arg1	groups					1069:1074	the abundant carboxyl groups	1047:1074	the abundant carboxyl groups in MEFB	1047:1082	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	2	20	theme	butylene	251:258	arg1	polylactide					228:238	A polylactide	226:238	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend	226:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	20	theme	butylene	251:258	arg1	adipate-co-terephthalate					260:283	butylene adipate-co-terephthalate	251:283	butylene adipate-co-terephthalate	251:283	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	8	21	theme	anionic	1133:1139	arg1	orange					1148:1153	anionic methyl orange	1133:1153	anionic methyl orange (MO)	1133:1158	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	8	21	theme	anionic	1133:1139	arg1	MO					1156:1157	MO	1156:1157	MO	1156:1157	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	10	22	theme	selective	1508:1516	arg1	filtration					1518:1527	selective filtration	1508:1527	selective filtration	1508:1527	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	10	23	theme	economical	1431:1440	arg1	preparation					1442:1452	its economical preparation	1427:1452	its economical preparation	1427:1452	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	10	24	used	used	1499:1502	arg2	membrane					1481:1488	the proposed biocomposite membrane	1455:1488	the proposed biocomposite membrane	1455:1488	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	4	25	theme	dye	637:639	arg1	adsorption					610:619	the adsorption	606:619	the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes	606:699	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	0	26	theme	Selective	0:8	arg1	separation					10:19	Selective separation	0:19	Selective separation of dyes by green composite membrane	0:55	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	4	27	theme	batch	512:516	arg1	process					529:535	a batch adsorption process	510:535	a batch adsorption process	510:535	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	7	28	theme	adsorption	998:1007	arg1	efficiency					1009:1018	its adsorption efficiency	994:1018	its adsorption efficiency toward MB	994:1028	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	2	29	theme	polymer	293:299	arg1	blend					301:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend	226:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend	226:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	4	30	from	adsorption	610:619	arg1	PLA/PBAT					664:671	PLA/PBAT	664:671	PLA/PBAT	664:671	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	4	30	from	adsorption	610:619	arg1	membranes					691:699	PLA/PBAT-MEFB membranes	677:699	PLA/PBAT-MEFB membranes	677:699	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	2	31	theme	fruit	369:373	arg1	EFB					382:384	EFB	382:384	EFB	382:384	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	31	theme	fruit	369:373	arg1	bunch					375:379	empty fruit bunch	363:379	empty fruit bunch (EFB) modified with maleic anhydride (MEFB)	363:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	0	32	theme	dyes	24:27	arg1	separation					10:19	Selective separation	0:19	Selective separation of dyes by green composite membrane	0:55	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	8	33	theme	PLA/PBAT-MEFB	1183:1195	arg1	membrane					1197:1204	the PLA/PBAT-MEFB membrane	1179:1204	the PLA/PBAT-MEFB membrane	1179:1204	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	0	34	theme	fruit	128:132	arg1	bunch					134:138	empty fruit bunch	122:138	empty fruit bunch	122:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	8	35	theme	dye	1117:1119	arg1	solution					1121:1128	a mixed dye solution	1109:1128	a mixed dye solution of anionic methyl orange (MO) and MB	1109:1165	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	1	36	theme	induced	192:198	arg1	process					217:223	a non-solvent induced phase separation process	178:223	a non-solvent induced phase separation process	178:223	A bio-based membrane was prepared by a non-solvent induced phase separation process.					
36435461	4	37	theme	PLA/PBAT-MEFB	677:689	arg1	membranes					691:699	PLA/PBAT-MEFB membranes	677:699	PLA/PBAT-MEFB membranes	677:699	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	0	38	theme	empty	122:126	arg1	bunch					134:138	empty fruit bunch	122:138	empty fruit bunch	122:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	1	39	theme	phase	200:204	arg1	process					217:223	a non-solvent induced phase separation process	178:223	a non-solvent induced phase separation process	178:223	A bio-based membrane was prepared by a non-solvent induced phase separation process.					
36435461	0	40	theme	green	32:36	arg1	membrane					48:55	green composite membrane	32:55	green composite membrane	32:55	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	4	41	theme	adsorption	518:527	arg1	process					529:535	a batch adsorption process	510:535	a batch adsorption process	510:535	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	8	42	theme	MB	1164:1165	arg1	solution					1121:1128	a mixed dye solution	1109:1128	a mixed dye solution of anionic methyl orange (MO) and MB	1109:1165	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	1	43	theme	non-solvent	180:190	arg1	process					217:223	a non-solvent induced phase separation process	178:223	a non-solvent induced phase separation process	178:223	A bio-based membrane was prepared by a non-solvent induced phase separation process.					
36435461	1	44	theme	separation	206:215	arg1	process					217:223	a non-solvent induced phase separation process	178:223	a non-solvent induced phase separation process	178:223	A bio-based membrane was prepared by a non-solvent induced phase separation process.					
36435461	4	45	theme	blue	651:654	arg1	dye					637:639	the cationic dye	624:639	the cationic dye methylene blue (MB)	624:659	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	5	46	theme	pure	735:738	arg1	flux					746:749	pure water flux	735:749	pure water flux	735:749	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	2	47	theme	polylactide	228:238	arg1	blend					301:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend	226:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend	226:305	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	48	from	bunch	375:379	arg1	microfiber					347:356	functionalized cellulose microfiber	322:356	functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB)	322:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	10	49	theme	proposed	1459:1466	arg1	membrane					1481:1488	the proposed biocomposite membrane	1455:1488	the proposed biocomposite membrane	1455:1488	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	5	50	theme	water	740:744	arg1	flux					746:749	pure water flux	735:749	pure water flux	735:749	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	6	51	theme	PLA/PBAT-MEFB	862:874	arg1	membrane					876:883	The PLA/PBAT-MEFB membrane	858:883	The PLA/PBAT-MEFB membrane	858:883	The PLA/PBAT-MEFB membrane removed 97.2 % of MB while the PLA/PBAT membrane removed only 58.7 %.					
36435461	8	52	theme	mixed	1111:1115	arg1	solution					1121:1128	a mixed dye solution	1109:1128	a mixed dye solution of anionic methyl orange (MO) and MB	1109:1165	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	9	53	theme	several	1373:1379	arg1	cycles					1381:1386	several cycles	1373:1386	several cycles	1373:1386	Moreover, this membrane could be easily regenerated and maintained a satisfactory separation performance over several cycles.					
36435461	2	54	theme	functionalized	322:335	arg1	microfiber					347:356	functionalized cellulose microfiber	322:356	functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB)	322:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	0	55	theme	composite	38:46	arg1	membrane					48:55	green composite membrane	32:55	green composite membrane	32:55	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	7	56	theme	membrane	981:988	arg1	efficiency					1009:1018	its adsorption efficiency	994:1018	its adsorption efficiency toward MB	994:1028	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	7	56	theme	membrane	981:988	arg1	hydrophilicity					959:972	The hydrophilicity	955:972	The hydrophilicity of the membrane	955:988	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	4	57	theme	cationic	628:635	arg1	dye					637:639	the cationic dye	624:639	the cationic dye methylene blue (MB)	624:659	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	7	58	theme	abundant	1051:1058	arg1	groups					1069:1074	the abundant carboxyl groups	1047:1074	the abundant carboxyl groups in MEFB	1047:1082	The hydrophilicity of the membrane and its adsorption efficiency toward MB were improved by the abundant carboxyl groups in MEFB.					
36435461	3	59	theme	water	443:447	arg1	angle					457:461	the water contact angle	439:461	the water contact angle	439:461	MEFB reduced the water contact angle and increased the porosity of the membrane.					
36435461	4	60	theme	Langmuir	566:573	arg1	models					584:589	Langmuir isotherm models	566:589	Langmuir isotherm models	566:589	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
36435461	3	61	theme	membrane	497:504	arg1	porosity					481:488	the porosity	477:488	the porosity of the membrane	477:504	MEFB reduced the water contact angle and increased the porosity of the membrane.					
36435461	8	62	theme	filtration	1087:1096	arg1	test					1098:1101	A filtration test	1085:1101	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB	1085:1165	A filtration test using a mixed dye solution of anionic methyl orange (MO) and MB showed that the PLA/PBAT-MEFB membrane rapidly adsorbed MB while permitting MO to pass through.					
36435461	3	63	theme	contact	449:455	arg1	angle					457:461	the water contact angle	439:461	the water contact angle	439:461	MEFB reduced the water contact angle and increased the porosity of the membrane.					
36435461	0	64	from	bunch	134:138	arg1	microfiber					106:115	carboxylated cellulose microfiber	83:115	carboxylated cellulose microfiber from empty fruit bunch	83:138	Selective separation of dyes by green composite membrane based on polylactide with carboxylated cellulose microfiber from empty fruit bunch.					
36435461	10	65	theme	membrane	1402:1409	arg1	performance					1411:1421	the membrane performance	1398:1421	the membrane performance	1398:1421	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	2	66	theme	maleic	401:406	arg1	MEFB					419:422	MEFB	419:422	MEFB	419:422	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	66	theme	maleic	401:406	arg1	anhydride					408:416	maleic anhydride	401:416	maleic anhydride (MEFB)	401:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	67	theme	empty	363:367	arg1	EFB					382:384	EFB	382:384	EFB	382:384	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	2	67	theme	empty	363:367	arg1	bunch					375:379	empty fruit bunch	363:379	empty fruit bunch (EFB) modified with maleic anhydride (MEFB)	363:423	A polylactide (PLA)/poly(butylene adipate-co-terephthalate) (PBAT) polymer blend was mixed with functionalized cellulose microfiber from empty fruit bunch (EFB) modified with maleic anhydride (MEFB).					
36435461	5	68	theme	dynamic	707:713	arg1	process					726:732	a dynamic adsorption process	705:732	a dynamic adsorption process	705:732	In a dynamic adsorption process, pure water flux was higher through the PLA/PBAT-MEFB membrane (1214 L m-2 h-1) than the PLA/PBAT membrane (371 L m-2 h-1).					
36435461	1	69	theme	bio-based	143:151	arg1	membrane					153:160	A bio-based membrane	141:160	A bio-based membrane	141:160	A bio-based membrane was prepared by a non-solvent induced phase separation process.					
36435461	10	70	theme	wastewater	1533:1542	arg1	treatment					1544:1552	wastewater treatment	1533:1552	wastewater treatment	1533:1552	Based on the membrane performance and its economical preparation, the proposed biocomposite membrane could be used for selective filtration and wastewater treatment.					
36435461	4	71	theme	isotherm	575:582	arg1	models					584:589	Langmuir isotherm models	566:589	Langmuir isotherm models	566:589	In a batch adsorption process, the pseudo-second order and Langmuir isotherm models best described the adsorption of the cationic dye methylene blue (MB) on PLA/PBAT and PLA/PBAT-MEFB membranes.					
35228076	8	0	theme	metal	1063:1067	arg1	ions					1069:1072	common metal ions	1056:1072	common metal ions in single-metal systems	1056:1096	Moreover, common metal ions in single-metal systems only slightly affected this process.					
35228076	9	1	theme	characterization	1163:1178	arg1	results					1139:1145	The results	1135:1145	The results of instrumental characterization and natural water application	1135:1208	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	0	2	theme	chitosan	101:108	arg1	investigation					16:28	investigation	16:28	investigation	16:28	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	0	2	theme	chitosan	101:108	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	5	3	theme	Batch	746:750	arg1	experiments					752:762	Batch experiments	746:762	Batch experiments	746:762	Batch experiments indicated that the pH and adsorbent dose strongly influenced UO22+ adsorption.					
35228076	8	4	theme	single-metal	1077:1088	arg1	systems					1090:1096	single-metal systems	1077:1096	single-metal systems	1077:1096	Moreover, common metal ions in single-metal systems only slightly affected this process.					
35228076	0	5	theme	efficient	121:129	arg1	adsorption					131:140	highly efficient adsorption	114:140	highly efficient adsorption of uranyl ions from radioactive effluents	114:182	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	10	6	theme	radioactive	1614:1624	arg1	effluents					1626:1634	radioactive effluents	1614:1634	radioactive effluents	1614:1634	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	9	7	theme	dominant	1329:1336	arg1	structure					1251:1259	the highly developed pore structure	1225:1259	the highly developed pore structure	1225:1259	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	7	theme	dominant	1329:1336	arg1	contributors					1349:1360	dominant adsorption contributors	1329:1360	dominant adsorption contributors besides amino and hydroxyl groups	1329:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	8	theme	natural	1184:1190	arg1	application					1198:1208	natural water application	1184:1208	natural water application	1184:1208	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	10	9	theme	chitosan	1555:1562	arg1	modification					1564:1575	chitosan modification	1555:1575	chitosan modification	1555:1575	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	9	10	theme	adsorption	1338:1347	arg1	structure					1251:1259	the highly developed pore structure	1225:1259	the highly developed pore structure	1225:1259	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	10	theme	adsorption	1338:1347	arg1	contributors					1349:1360	dominant adsorption contributors	1329:1360	dominant adsorption contributors besides amino and hydroxyl groups	1329:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	11	theme	water	1192:1196	arg1	application					1198:1208	natural water application	1184:1208	natural water application	1184:1208	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	0	12	from	effluents	174:182	arg1	adsorption					131:140	highly efficient adsorption	114:140	highly efficient adsorption of uranyl ions from radioactive effluents	114:182	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	10	13	theme	modification	1564:1575	arg1	practices					1601:1609	chitosan modification and further remediation practices	1555:1609	chitosan modification and further remediation practices of radioactive effluents	1555:1634	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	7	14	theme	UO22+	965:969	arg1	adsorption					971:980	UO22+ adsorption	965:980	UO22+ adsorption by MCTPP	965:989	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	7	14	theme	UO22+	965:969	arg1	process					1037:1043	an endothermic single-layer adsorption process	998:1043	an endothermic single-layer adsorption process	998:1043	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	10	15	theme	mechanism	1511:1519	arg1	identification					1478:1491	identification	1478:1491	identification	1478:1491	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	10	15	theme	mechanism	1511:1519	arg1	UO22+					1468:1472	UO22+	1468:1472	UO22+	1468:1472	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	10	16	theme	effluents	1626:1634	arg1	practices					1601:1609	chitosan modification and further remediation practices	1555:1609	chitosan modification and further remediation practices of radioactive effluents	1555:1634	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	10	17	theme	valuable	1534:1541	arg1	guidance					1543:1550	valuable guidance	1534:1550	valuable guidance to chitosan modification and further remediation practices of radioactive effluents	1534:1634	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	1	18	theme	potassium	211:219	arg1	tripolyphosphate					221:236	potassium tripolyphosphate	211:236	potassium tripolyphosphate (CTPP)	211:243	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	1	18	theme	potassium	211:219	arg1	CTPP					239:242	CTPP	239:242	CTPP	239:242	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	9	19	theme	amino	1370:1374	arg1	groups					1389:1394	amino and hydroxyl groups	1370:1394	groups	1389:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	20	from	groups	1291:1296	arg1	composites					1313:1322	synthesized composites	1301:1322	synthesized composites	1301:1322	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	7	21	theme	adsorption	1026:1035	arg1	adsorption					971:980	UO22+ adsorption	965:980	UO22+ adsorption by MCTPP	965:989	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	7	21	theme	adsorption	1026:1035	arg1	process					1037:1043	an endothermic single-layer adsorption process	998:1043	an endothermic single-layer adsorption process	998:1043	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	10	22	theme	material	1433:1440	arg1	development					1408:1418	Successful development	1397:1418	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism	1397:1519	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	5	23	theme	UO22+	825:829	arg1	adsorption					831:840	UO22+ adsorption	825:840	UO22+ adsorption	825:840	Batch experiments indicated that the pH and adsorbent dose strongly influenced UO22+ adsorption.					
35228076	10	24	theme	Successful	1397:1406	arg1	development					1408:1418	Successful development	1397:1418	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism	1397:1519	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	4	25	theme	pure	662:665	arg1	chitosan					667:674	chitosan	667:674	chitosan	667:674	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP were 374.93, 780.89, and 1487.72 mg/g, respectively.					
35228076	0	26	theme	ions	152:155	arg1	adsorption					131:140	highly efficient adsorption	114:140	highly efficient adsorption of uranyl ions from radioactive effluents	114:182	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	9	27	theme	hydroxyl	1380:1387	arg1	groups					1389:1394	amino and hydroxyl groups	1370:1394	groups	1389:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	7	28	theme	adsorption	929:938	arg1	isotherms					940:948	The adsorption isotherms	925:948	The adsorption isotherms	925:948	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	2	29	theme	process	508:514	arg1	mechanisms					479:488	interactive mechanisms	467:488	interactive mechanisms	467:488	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	2	29	theme	process	508:514	arg1	factors					428:434	The influential factors	412:434	The influential factors	412:434	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	2	29	theme	process	508:514	arg1	requirements					449:460	operational requirements	437:460	operational requirements	437:460	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	0	30	theme	uranyl	145:150	arg1	ions					152:155	uranyl ions	145:155	uranyl ions	145:155	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	10	31	theme	remediation	1589:1599	arg1	practices					1601:1609	chitosan modification and further remediation practices	1555:1609	chitosan modification and further remediation practices of radioactive effluents	1555:1634	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	9	32	theme	developed	1236:1244	arg1	structure					1251:1259	the highly developed pore structure	1225:1259	the highly developed pore structure	1225:1259	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	32	theme	developed	1236:1244	arg1	contributors					1349:1360	dominant adsorption contributors	1329:1360	dominant adsorption contributors besides amino and hydroxyl groups	1329:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	2	33	theme	adsorption	497:506	arg1	process					508:514	the adsorption process	493:514	the adsorption process	493:514	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	0	34	theme	monochloroacetic	39:54	arg1	chitosan					101:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	9	35	theme	application	1198:1208	arg1	results					1139:1145	The results	1135:1145	The results of instrumental characterization and natural water application	1135:1208	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	0	36	theme	radioactive	162:172	arg1	effluents					174:182	radioactive effluents	162:182	radioactive effluents	162:182	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	0	37	dep	fortified	61:69	arg1	tripolyphosphate-crosslinked					72:99	tripolyphosphate-crosslinked	72:99	tripolyphosphate-crosslinked	72:99	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	9	38	theme	pore	1246:1249	arg1	structure					1251:1259	the highly developed pore structure	1225:1259	the highly developed pore structure	1225:1259	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	38	theme	pore	1246:1249	arg1	contributors					1349:1360	dominant adsorption contributors	1329:1360	dominant adsorption contributors besides amino and hydroxyl groups	1329:1394	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	9	39	from	structure	1251:1259	arg1	composites					1313:1322	synthesized composites	1301:1322	synthesized composites	1301:1322	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	0	40	theme	novel	33:37	arg1	chitosan					101:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	4	41	theme	adsorption	636:645	arg1	capacities					647:656	The maximum adsorption capacities	624:656	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP	624:691	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP were 374.93, 780.89, and 1487.72 mg/g, respectively.					
35228076	4	41	theme	adsorption	636:645	arg1	374.93					698:703	374.93	698:703	374.93	698:703	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP were 374.93, 780.89, and 1487.72 mg/g, respectively.					
35228076	10	42	theme	novel	1427:1431	arg1	material					1433:1440	the novel material	1423:1440	the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism	1423:1519	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	1	43	theme	monochloroacetic-acid-modified	249:278	arg1	chitosan					280:287	monochloroacetic-acid-modified chitosan	249:287	monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP)	249:339	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	0	44	theme	fortified	61:69	arg1	chitosan					101:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	4	45	theme	maximum	628:634	arg1	capacities					647:656	The maximum adsorption capacities	624:656	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP	624:691	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP were 374.93, 780.89, and 1487.72 mg/g, respectively.					
35228076	4	45	theme	maximum	628:634	arg1	374.93					698:703	374.93	698:703	374.93	698:703	The maximum adsorption capacities for pure chitosan, CTPP, and MCTPP were 374.93, 780.89, and 1487.72 mg/g, respectively.					
35228076	10	46	theme	further	1581:1587	arg1	remediation					1589:1599	further remediation	1581:1599	further remediation	1581:1599	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	6	47	theme	most	862:865	arg1	UO22+					867:871	most UO22+	862:871	most UO22+	862:871	MCTPP could adsorb most UO22+ within 15 min, and equilibrium was reached by ~1 h.					
35228076	2	48	theme	influential	416:426	arg1	factors					428:434	The influential factors	412:434	The influential factors	412:434	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	0	49	theme	acid	56:59	arg1	chitosan					101:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan	33:108	Fabrication and investigation of novel monochloroacetic acid fortified, tripolyphosphate-crosslinked chitosan for highly efficient adsorption of uranyl ions from radioactive effluents.					
35228076	1	50	theme	acidic	382:387	arg1	effluents					401:409	acidic radioactive effluents	382:409	acidic radioactive effluents	382:409	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	5	51	theme	adsorbent	790:798	arg1	dose					800:803	adsorbent dose	790:803	adsorbent dose	790:803	Batch experiments indicated that the pH and adsorbent dose strongly influenced UO22+ adsorption.					
35228076	9	52	theme	abundant	1265:1272	arg1	groups					1291:1296	abundant tripolyphosphate groups	1265:1296	abundant tripolyphosphate groups	1265:1296	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	7	53	theme	endothermic	1001:1011	arg1	adsorption					971:980	UO22+ adsorption	965:980	UO22+ adsorption by MCTPP	965:989	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	7	53	theme	endothermic	1001:1011	arg1	process					1037:1043	an endothermic single-layer adsorption process	998:1043	an endothermic single-layer adsorption process	998:1043	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	1	54	theme	radioactive	389:399	arg1	effluents					401:409	acidic radioactive effluents	382:409	acidic radioactive effluents	382:409	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	9	55	theme	tripolyphosphate	1274:1289	arg1	groups					1291:1296	abundant tripolyphosphate groups	1265:1296	abundant tripolyphosphate groups	1265:1296	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	7	56	theme	single-layer	1013:1024	arg1	adsorption					971:980	UO22+ adsorption	965:980	UO22+ adsorption by MCTPP	965:989	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	7	56	theme	single-layer	1013:1024	arg1	process					1037:1043	an endothermic single-layer adsorption process	998:1043	an endothermic single-layer adsorption process	998:1043	The adsorption isotherms indicated that UO22+ adsorption by MCTPP may be an endothermic single-layer adsorption process.					
35228076	10	57	theme	adsorption	1500:1509	arg1	mechanism					1511:1519	the adsorption mechanism	1496:1519	the adsorption mechanism	1496:1519	Successful development of the novel material for efficiently adsorbing UO22+ and identification of the adsorption mechanism will provide valuable guidance to chitosan modification and further remediation practices of radioactive effluents.					
35228076	8	58	theme	common	1056:1061	arg1	ions					1069:1072	common metal ions	1056:1072	common metal ions in single-metal systems	1056:1096	Moreover, common metal ions in single-metal systems only slightly affected this process.					
35228076	3	59	theme	mesh-structured	554:568	arg1	composites					570:579	The mesh-structured composites	550:579	The mesh-structured composites	550:579	The mesh-structured composites adsorbed UO22+ most effectively at pH 5.0.					
35228076	8	60	from	ions	1069:1072	arg1	systems					1090:1096	single-metal systems	1077:1096	single-metal systems	1077:1096	Moreover, common metal ions in single-metal systems only slightly affected this process.					
35228076	2	61	theme	interactive	467:477	arg1	mechanisms					479:488	interactive mechanisms	467:488	interactive mechanisms	467:488	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	9	62	theme	synthesized	1301:1311	arg1	composites					1313:1322	synthesized composites	1301:1322	synthesized composites	1301:1322	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	2	63	theme	operational	437:447	arg1	requirements					449:460	operational requirements	437:460	operational requirements	437:460	The influential factors, operational requirements, and interactive mechanisms of the adsorption process were systematically investigated.					
35228076	9	64	theme	instrumental	1150:1161	arg1	characterization					1163:1178	instrumental characterization	1150:1178	instrumental characterization	1150:1178	The results of instrumental characterization and natural water application suggested that the highly developed pore structure and abundant tripolyphosphate groups in synthesized composites were dominant adsorption contributors besides amino and hydroxyl groups.					
35228076	1	65	theme	potassium	306:314	arg1	MCTPP					334:338	MCTPP	334:338	MCTPP	334:338	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35228076	1	65	theme	potassium	306:314	arg1	tripolyphosphate					316:331	potassium tripolyphosphate	306:331	potassium tripolyphosphate (MCTPP)	306:339	Chitosan crosslinked with potassium tripolyphosphate (CTPP) and monochloroacetic-acid-modified chitosan crosslinked with potassium tripolyphosphate (MCTPP) were synthesized for removing UO22+ from acidic radioactive effluents.					
35570042	2	0	dep	lactose	465:471	arg1	pH					494:495	pH	494:495	pH	494:495	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	0	dep	lactose	465:471	arg1	count					487:491	somatic cell count	474:491	somatic cell count	474:491	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	0	dep	lactose	465:471	arg1	count					512:516	bacterial count	502:516	bacterial count	502:516	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	11	1	theme	mean	2378:2381	arg1	error					2390:2394	the root mean square error	2369:2394	the root mean square error of validation (RMSEVAL)	2369:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	7	2	theme	2	1392:1392	arg1	%					1394:1394	%	1394:1394	%	1394:1394	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	15	3	theme	direct	3083:3088	arg1	improvement					3098:3108	the direct genetic improvement	3079:3108	the direct genetic improvement of cheese production	3079:3129	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	3	4	dep	procedure	796:804	arg1	method					815:820	9-MilCA method	807:820	9-MilCA method	807:820	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	2	5	theme	somatic	474:480	arg1	count					487:491	somatic cell count	474:491	somatic cell count	474:491	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	3	6	theme	individual	760:769	arg1	procedure					796:804	an individual laboratory cheese-making procedure	757:804	an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations	757:885	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	2	7	theme	prediction	652:661	arg1	accuracy					663:670	prediction accuracy	652:670	prediction accuracy of the %CY formulas	652:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	9	8	theme	CY	1840:1841	arg1	formulas					1854:1861	the %CY predictive formulas	1835:1861	the %CY predictive formulas	1835:1861	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	6	9	theme	multiple	1166:1173	arg1	models					1193:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	11	10	theme	validation	2399:2408	arg1	error					2390:2394	the root mean square error	2369:2394	the root mean square error of validation (RMSEVAL)	2369:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	11	10	theme	validation	2399:2408	arg1	R2VAL					2358:2362	R2VAL	2358:2362	R2VAL	2358:2362	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	11	10	theme	validation	2399:2408	arg1	validation					2346:2355	validation	2346:2355	validation (R2VAL)	2346:2363	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	15	11	theme	milk	3004:3007	arg1	traits					3009:3014	milk traits	3004:3014	milk traits	3004:3014	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	12	12	with	formula	2433:2439	arg1	accuracy					2466:2473	the best prediction accuracy	2446:2473	the best prediction accuracy	2446:2473	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	13	13	theme	low	2686:2688	arg1	effect					2690:2695	a low effect	2684:2695	a low effect of the 9-MilCA method and, indirectly, its high repeatability	2684:2757	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	3	14	dep	method	815:820	arg1	mL					825:826	9 mL	823:826	9 mL of milk per observation	823:850	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	6	15	theme	Single	1155:1160	arg1	models					1193:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	10	16	theme	best	2173:2176	arg1	model					2178:2182	the best model	2169:2182	the best model	2169:2182	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	1	17	theme	milk	173:176	arg1	composition					178:188	milk composition	173:188	milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	173:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	2	18	theme	udder	440:444	arg1	indicators					453:462	udder health indicators	440:462	udder health indicators (lactose, somatic cell count, pH, and bacterial count)	440:517	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	3	19	theme	cheese-making	782:794	arg1	procedure					796:804	an individual laboratory cheese-making procedure	757:804	an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations	757:885	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	12	20	theme	%	2558:2558	arg1	CYCURD					2559:2564	%CYCURD	2558:2564	%CYCURD	2558:2564	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	15	21	theme	breeds	3063:3068	arg1	indices					3043:3049	the composite selection indices	3019:3049	the composite selection indices of specific breeds	3019:3068	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	2	22	from	effects	641:647	arg1	accuracy					663:670	prediction accuracy	652:670	prediction accuracy of the %CY formulas	652:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	6	23	theme	health	1309:1314	arg1	indicators					1316:1325	indirect udder health indicators	1294:1325	indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1294:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	9	24	dep	formula	1767:1773	arg1	i.e.					1747:1750	i.e.	1747:1750	i.e.	1747:1750	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	9	25	theme	cheese-making	1889:1901	arg1	procedure					1903:1911	the laboratory cheese-making procedure	1874:1911	the laboratory cheese-making procedure (within-animal validation, WAV)	1874:1943	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	1	26	theme	goat	204:207	arg1	samples					209:215	individual goat samples	193:215	individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	193:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	6	27	theme	indirect	1294:1301	arg1	indicators					1316:1325	indirect udder health indicators	1294:1325	indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1294:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	15	28	theme	specific	3054:3061	arg1	breeds					3063:3068	specific breeds	3054:3068	specific breeds	3054:3068	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	10	29	theme	CY	2107:2108	arg1	accuracy					2128:2135	the %CY traits prediction accuracy	2102:2135	the %CY traits prediction accuracy	2102:2135	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	11	30	theme	Fitting	2262:2268	arg1	statistics					2270:2279	Fitting statistics	2262:2279	Fitting statistics of the formulas	2262:2295	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	0	31	from	samples	103:109	arg1	composition					70:80	milk composition	65:80	milk composition from individual goat samples	65:109	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	2	32	theme	fresh	534:538	arg1	traits					526:531	%CY traits	522:531	%CY traits (fresh curd, milk solids, and water retained in the curd)	522:589	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	32	theme	fresh	534:538	arg1	curd					540:543	fresh curd	534:543	fresh curd	534:543	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	15	33	from	influence	2991:2999	arg1	indices					3043:3049	the composite selection indices	3019:3049	the composite selection indices of specific breeds	3019:3068	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	13	34	theme	method	2712:2717	arg1	effect					2690:2695	a low effect	2684:2695	a low effect of the 9-MilCA method and, indirectly, its high repeatability	2684:2757	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	15	35	theme	composite	3023:3031	arg1	indices					3043:3049	the composite selection indices	3019:3049	the composite selection indices of specific breeds	3019:3068	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	9	36	theme	prediction	1719:1728	arg1	accuracy					1730:1737	the best prediction accuracy	1710:1737	the best prediction accuracy	1710:1737	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	15	37	theme	cheese	3113:3118	arg1	production					3120:3129	cheese production	3113:3129	cheese production	3113:3129	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	6	38	theme	regression	1182:1191	arg1	models					1193:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	13	39	theme	repeatability	2745:2757	arg1	effect					2690:2695	a low effect	2684:2695	a low effect of the 9-MilCA method and, indirectly, its high repeatability	2684:2757	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	2	40	theme	components	398:407	arg1	fat					410:412	fat	410:412	fat	410:412	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	40	theme	components	398:407	arg1	contribution					371:382	the contribution	367:382	(1) the contribution of major milk components	363:407	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	40	theme	components	398:407	arg1	casein					428:433	casein	428:433	casein	428:433	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	40	theme	components	398:407	arg1	protein					415:421	protein	415:421	protein	415:421	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	40	theme	components	398:407	arg1	indicators					453:462	udder health indicators	440:462	udder health indicators (lactose, somatic cell count, pH, and bacterial count)	440:517	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	6	41	theme	cell	1350:1353	arg1	count					1355:1359	somatic cell count	1342:1359	somatic cell count	1342:1359	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	12	42	theme	%	2582:2582	arg1	CYWATER					2583:2589	%CYWATER	2582:2589	%CYWATER	2582:2589	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	1	43	dep	traits	251:256	arg1	water					288:292	water	288:292	water	288:292	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	43	dep	traits	251:256	arg1	traits					251:256	cheese yield (%CY) traits	232:256	cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	232:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	43	dep	traits	251:256	arg1	curd					265:268	fresh curd	259:268	fresh curd	259:268	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	43	dep	traits	251:256	arg1	solids					276:281	milk solids	271:281	milk solids	271:281	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	0	44	theme	individual	87:96	arg1	samples					103:109	individual goat samples	87:109	individual goat samples	87:109	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	11	45	theme	formulas	2288:2295	arg1	statistics					2270:2279	Fitting statistics	2262:2279	Fitting statistics of the formulas	2262:2295	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	2	46	theme	bacterial	502:510	arg1	count					512:516	bacterial count	502:516	bacterial count	502:516	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	47	from	method	614:619	arg1	accuracy					663:670	prediction accuracy	652:670	prediction accuracy of the %CY formulas	652:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	12	48	theme	%	2567:2567	arg1	CYSOLIDS					2568:2575	%CYSOLIDS	2567:2575	%CYSOLIDS	2567:2575	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	9	49	theme	first	1959:1963	arg1	observation					1969:1979	the first %CY observation	1955:1979	the first %CY observation within animal	1955:1993	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	6	50	theme	components	1256:1265	arg1	combinations					1226:1237	different combinations	1216:1237	different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1216:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	51	dep	components	1256:1265	arg1	fat					1268:1270	fat	1268:1270	fat	1268:1270	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	51	dep	components	1256:1265	arg1	casein					1282:1287	casein	1282:1287	casein	1282:1287	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	51	dep	components	1256:1265	arg1	protein					1273:1279	protein	1273:1279	protein	1273:1279	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	15	52	theme	genetic	3090:3096	arg1	improvement					3098:3108	the direct genetic improvement	3079:3108	the direct genetic improvement of cheese production	3079:3129	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	5	53	theme	%	1039:1039	arg1	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	53	theme	%	1039:1039	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	53	theme	%	1039:1039	arg1	CYCURD					1045:1050	%CYCURD	1044:1050	%CYCURD	1044:1050	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	53	theme	%	1039:1039	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	53	theme	%	1039:1039	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	0	54	theme	Predictive	0:9	arg1	formulas					11:18	Predictive formulas	0:18	Predictive formulas for different measures of cheese	0:51	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	9	55	theme	CY	1966:1967	arg1	observation					1969:1979	the first %CY observation	1955:1979	the first %CY observation within animal	1955:1993	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	6	56	theme	standard	1242:1249	arg1	components					1256:1265	standard milk components	1242:1265	standard milk components (fat, protein, casein)	1242:1288	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	3	57	theme	%	697:697	arg1	traits					701:706	The %CY traits	693:706	The %CY traits	693:706	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	3	58	from	goats	744:748	arg1	duplicate					725:733	duplicate	725:733	duplicate from 600 goats	725:748	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	2	59	theme	CY	680:681	arg1	formulas					683:690	the %CY formulas	675:690	the %CY formulas	675:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	60	theme	%	522:522	arg1	traits					526:531	%CY traits	522:531	%CY traits (fresh curd, milk solids, and water retained in the curd)	522:589	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	60	theme	%	522:522	arg1	curd					540:543	fresh curd	534:543	fresh curd	534:543	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	60	theme	%	522:522	arg1	water					563:567	water	563:567	water	563:567	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	11	61	theme	determination	2329:2341	arg1	coefficient					2314:2324	coefficient	2314:2324	coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL)	2314:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	13	62	theme	WAV	2611:2613	arg1	procedure					2615:2623	The WAV procedure	2607:2623	The WAV procedure	2607:2623	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	5	63	from	solids	1060:1065	arg1	curd					1117:1120	the curd	1113:1120	the curd	1113:1120	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	2	64	theme	major	387:391	arg1	components					398:407	major milk components	387:407	major milk components	387:407	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	6	65	theme	bacterial	1370:1378	arg1	count					1380:1384	bacterial count	1370:1384	bacterial count	1370:1384	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	10	66	theme	stratified	2058:2067	arg1	SCrV					2074:2077	SCrV	2074:2077	SCrV	2074:2077	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	10	66	theme	stratified	2058:2067	arg1	CrV					2069:2071	a stratified CrV	2056:2071	a stratified CrV (SCrV)	2056:2078	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	14	67	theme	CY	2894:2895	arg1	formulas					2908:2915	%CY predictive formulas	2893:2915	%CY predictive formulas	2893:2915	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	12	68	dep	fat	2503:2505	arg1	=					2531:2531	=	2531:2531	=	2531:2531	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	12	69	theme	CY	2484:2485	arg1	traits					2487:2492	all %CY traits	2479:2492	all %CY traits	2479:2492	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	9	70	theme	secondary	1790:1798	arg1	analysis					1800:1807	a secondary analysis	1788:1807	a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV)	1788:1943	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	0	71	theme	cheese	46:51	arg1	measures					34:41	different measures	24:41	different measures of cheese	24:51	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	1	72	theme	milk	271:274	arg1	solids					276:281	milk solids	271:281	milk solids	271:281	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	3	73	theme	observations	874:885	arg1	total					859:863	a total	857:863	a total of 1,200 observations	857:885	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	5	74	theme	response	1135:1142	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	74	theme	response	1135:1142	arg1	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	74	theme	response	1135:1142	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	74	theme	response	1135:1142	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	12	75	theme	best	2450:2453	arg1	accuracy					2466:2473	the best prediction accuracy	2446:2473	the best prediction accuracy	2446:2473	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	1	76	theme	samples	209:215	arg1	composition					178:188	milk composition	173:188	milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	173:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	9	77	theme	formulas	1854:1861	arg1	accuracy					1823:1830	the accuracy	1819:1830	the accuracy of the %CY predictive formulas	1819:1861	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	7	78	theme	%	1394:1394	arg1	observations					1398:1409	The 2 %CY observations	1388:1409	The 2 %CY observations within animal	1388:1423	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	15	79	theme	selection	3033:3041	arg1	indices					3043:3049	the composite selection indices	3019:3049	the composite selection indices of specific breeds	3019:3068	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	2	80	theme	breed	635:639	arg1	effects					641:647	(3) goat breed effects	626:647	(3) goat breed effects on prediction accuracy of the %CY formulas	626:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	14	81	theme	%	2795:2795	arg1	CYCURD					2796:2801	%CYCURD	2795:2801	%CYCURD	2795:2801	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	15	82	theme	traits	3009:3014	arg1	influence					2991:2999	the influence	2987:2999	the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production	2987:3129	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	1	83	theme	yield	239:243	arg1	water					288:292	water	288:292	water	288:292	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	83	theme	yield	239:243	arg1	traits					251:256	cheese yield (%CY) traits	232:256	cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	232:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	83	theme	yield	239:243	arg1	curd					265:268	fresh curd	259:268	fresh curd	259:268	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	11	84	theme	square	2383:2388	arg1	error					2390:2394	the root mean square error	2369:2394	the root mean square error of validation (RMSEVAL)	2369:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	2	85	theme	cell	482:485	arg1	count					487:491	somatic cell count	474:491	somatic cell count	474:491	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	10	86	theme	remaining	2232:2240	arg1	one					2242:2244	the remaining one	2228:2244	the remaining one	2228:2244	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	9	87	theme	%	1839:1839	arg1	formulas					1854:1861	the %CY predictive formulas	1835:1861	the %CY predictive formulas	1835:1861	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	1	88	theme	%	246:246	arg1	yield					239:243	cheese yield	232:243	cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	232:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	88	theme	%	246:246	arg1	CY					247:248	%CY	246:248	%CY	246:248	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	9	89	theme	VAL	2038:2040	arg1	set					2042:2044	the VAL set	2034:2044	the VAL set	2034:2044	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	15	90	theme	production	3120:3129	arg1	improvement					3098:3108	the direct genetic improvement	3079:3108	the direct genetic improvement of cheese production	3079:3129	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	5	91	theme	retained	1090:1097	arg1	CYWATER					1101:1107	%CYWATER	1100:1107	%CYWATER	1100:1107	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	91	theme	retained	1090:1097	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	91	theme	retained	1090:1097	arg1	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	91	theme	retained	1090:1097	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	91	theme	retained	1090:1097	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	9	92	theme	predictive	1843:1852	arg1	formulas					1854:1861	the %CY predictive formulas	1835:1861	the %CY predictive formulas	1835:1861	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	14	93	theme	large	2773:2777	arg1	differences					2779:2789	large differences	2773:2789	large differences for %CYCURD and %CYWATER among breeds	2773:2827	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	5	94	theme	%	1068:1068	arg1	CYSOLIDS					1069:1076	%CYSOLIDS	1068:1076	%CYSOLIDS	1068:1076	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	94	theme	%	1068:1068	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	13	95	theme	9-MilCA	2704:2710	arg1	method					2712:2717	the 9-MilCA method	2700:2717	the 9-MilCA method	2700:2717	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	7	96	theme	calibration	1548:1558	arg1	set					1566:1568	the calibration (CAL) set	1544:1568	the calibration (CAL) set	1544:1568	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	2	97	dep	method	614:619	arg1	2					593:593	2	593:593	2	593:593	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	3	98	theme	laboratory	771:780	arg1	procedure					796:804	an individual laboratory cheese-making procedure	757:804	an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations	757:885	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	14	99	theme	%	2807:2807	arg1	CYWATER					2808:2814	%CYWATER	2807:2814	%CYWATER	2807:2814	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	11	100	theme	validation	2346:2355	arg1	determination					2329:2341	determination	2329:2341	determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL)	2329:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	6	101	theme	indicators	1316:1325	arg1	combinations					1226:1237	different combinations	1216:1237	different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1216:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	7	102	theme	validation	1585:1594	arg1	set					1602:1604	the validation (VAL) set	1581:1604	the validation (VAL) set	1581:1604	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	9	103	theme	laboratory	1878:1887	arg1	procedure					1903:1911	the laboratory cheese-making procedure	1874:1911	the laboratory cheese-making procedure (within-animal validation, WAV)	1874:1943	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	1	104	theme	individual	193:202	arg1	samples					209:215	individual goat samples	193:215	individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	193:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	11	105	theme	root	2373:2376	arg1	error					2390:2394	the root mean square error	2369:2394	the root mean square error of validation (RMSEVAL)	2369:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	6	106	theme	udder	1303:1307	arg1	indicators					1316:1325	indirect udder health indicators	1294:1325	indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1294:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	2	107	theme	milk	546:549	arg1	solids					551:556	milk solids	546:556	milk solids	546:556	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	9	108	theme	procedure	1903:1911	arg1	part					1866:1869	part	1866:1869	part of the laboratory cheese-making procedure (within-animal validation, WAV)	1866:1943	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	6	109	theme	different	1216:1224	arg1	combinations					1226:1237	different combinations	1216:1237	different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count)	1216:1385	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	7	110	theme	observations	1505:1516	arg1	observations					1505:1516	observations	1505:1516	observations	1505:1516	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	7	110	theme	observations	1505:1516	arg1	%					1500:1500	80%	1498:1500	80% of observations	1498:1516	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	6	111	dep	indicators	1316:1325	arg1	UHI					1328:1330	UHI	1328:1330	UHI	1328:1330	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	10	112	theme	traits	2110:2115	arg1	accuracy					2128:2135	the %CY traits prediction accuracy	2102:2135	the %CY traits prediction accuracy	2102:2135	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	11	113	theme	error	2390:2394	arg1	determination					2329:2341	determination	2329:2341	determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL)	2329:2418	Fitting statistics of the formulas were assessed by coefficient of determination of validation (R2VAL) and the root mean square error of validation (RMSEVAL).					
35570042	9	114	theme	within-animal	1914:1926	arg1	validation					1928:1937	within-animal validation	1914:1937	within-animal validation	1914:1937	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	9	114	theme	within-animal	1914:1926	arg1	WAV					1940:1942	WAV	1940:1942	WAV	1940:1942	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	10	115	theme	VAL	2253:2255	arg1	set					2257:2259	the VAL set	2249:2259	the VAL set	2249:2259	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	6	116	dep	UHI	1328:1330	arg1	count					1380:1384	bacterial count	1370:1384	bacterial count	1370:1384	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	116	dep	UHI	1328:1330	arg1	lactose					1333:1339	lactose	1333:1339	lactose	1333:1339	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	116	dep	UHI	1328:1330	arg1	pH					1362:1363	pH	1362:1363	pH	1362:1363	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	6	116	dep	UHI	1328:1330	arg1	count					1355:1359	somatic cell count	1342:1359	somatic cell count	1342:1359	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	2	117	theme	health	446:451	arg1	indicators					453:462	udder health indicators	440:462	udder health indicators (lactose, somatic cell count, pH, and bacterial count)	440:517	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	10	118	theme	%	2106:2106	arg1	accuracy					2128:2135	the %CY traits prediction accuracy	2102:2135	the %CY traits prediction accuracy	2102:2135	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	9	119	theme	best	1714:1717	arg1	accuracy					1730:1737	the best prediction accuracy	1710:1737	the best prediction accuracy	1710:1737	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	0	120	theme	milk	65:68	arg1	composition					70:80	milk composition	65:80	milk composition from individual goat samples	65:109	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	1	121	theme	study	134:138	arg1	objective					116:124	The objective	112:124	The objective of this study	112:138	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	2	122	dep	traits	526:531	arg1	traits					526:531	%CY traits	522:531	%CY traits (fresh curd, milk solids, and water retained in the curd)	522:589	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	122	dep	traits	526:531	arg1	curd					540:543	fresh curd	534:543	fresh curd	534:543	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	122	dep	traits	526:531	arg1	solids					551:556	milk solids	546:556	milk solids	546:556	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	122	dep	traits	526:531	arg1	water					563:567	water	563:567	water	563:567	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	10	123	theme	goat	2144:2147	arg1	breeds					2149:2154	goat breeds	2144:2154	goat breeds	2144:2154	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	7	124	theme	VAL	1597:1599	arg1	set					1602:1604	the validation (VAL) set	1581:1604	the validation (VAL) set	1581:1604	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	2	125	dep	contribution	371:382	arg1	1					364:364	1	364:364	1	364:364	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	6	126	theme	linear	1175:1180	arg1	models					1193:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models	1155:1198	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	2	127	theme	milk	393:396	arg1	components					398:407	major milk components	387:407	major milk components	387:407	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	6	128	theme	somatic	1342:1348	arg1	count					1355:1359	somatic cell count	1342:1359	somatic cell count	1342:1359	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	2	129	from	traits	526:531	arg1	accuracy					663:670	prediction accuracy	652:670	prediction accuracy of the %CY formulas	652:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	0	130	theme	goat	98:101	arg1	samples					103:109	individual goat samples	87:109	individual goat samples	87:109	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	3	131	theme	9-MilCA	807:813	arg1	method					815:820	9-MilCA method	807:820	9-MilCA method	807:820	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	14	132	theme	fundamental	2859:2869	arg1	breed					2848:2852	the breed	2844:2852	the breed	2844:2852	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	14	132	theme	fundamental	2859:2869	arg1	factor					2871:2876	a fundamental factor	2857:2876	a fundamental factor to consider in %CY predictive formulas	2857:2915	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	13	133	dep	higher	2638:2643	arg1	R2VAL					2632:2636	R2VAL	2632:2636	R2VAL	2632:2636	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	3	134	theme	milk	831:834	arg1	mL					825:826	9 mL	823:826	9 mL of milk per observation	823:850	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	9	135	dep	procedure	1903:1911	arg1	validation					1928:1937	within-animal validation	1914:1937	within-animal validation	1914:1937	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	9	135	dep	procedure	1903:1911	arg1	WAV					1940:1942	WAV	1940:1942	WAV	1940:1942	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	5	136	theme	%	1100:1100	arg1	CYWATER					1101:1107	%CYWATER	1100:1107	%CYWATER	1100:1107	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	136	theme	%	1100:1100	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	137	theme	Fresh	1033:1037	arg1	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	137	theme	Fresh	1033:1037	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	137	theme	Fresh	1033:1037	arg1	CYCURD					1045:1050	%CYCURD	1044:1050	%CYCURD	1044:1050	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	137	theme	Fresh	1033:1037	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	137	theme	Fresh	1033:1037	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	2	138	theme	specific	321:328	arg1	aims					330:333	The specific aims	317:333	The specific aims	317:333	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	9	139	theme	%	1965:1965	arg1	observation					1969:1979	the first %CY observation	1955:1979	the first %CY observation within animal	1955:1993	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	6	140	theme	milk	1251:1254	arg1	components					1256:1265	standard milk components	1242:1265	standard milk components (fat, protein, casein)	1242:1288	Single and multiple linear regression models were tested via different combinations of standard milk components (fat, protein, casein) and indirect udder health indicators (UHI; lactose, somatic cell count, pH, and bacterial count).					
35570042	13	141	theme	high	2740:2743	arg1	repeatability					2745:2757	its high repeatability	2736:2757	its high repeatability	2736:2757	The WAV procedure showed R2VAL higher than those obtained in CrV, evidencing a low effect of the 9-MilCA method and, indirectly, its high repeatability.					
35570042	5	142	from	CY	1040:1041	arg1	curd					1117:1120	the curd	1113:1120	the curd	1113:1120	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	2	143	theme	formulas	683:690	arg1	accuracy					663:670	prediction accuracy	652:670	prediction accuracy of the %CY formulas	652:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	144	theme	CY	523:524	arg1	traits					526:531	%CY traits	522:531	%CY traits (fresh curd, milk solids, and water retained in the curd)	522:589	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	144	theme	CY	523:524	arg1	curd					540:543	fresh curd	534:543	fresh curd	534:543	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	144	theme	CY	523:524	arg1	water					563:567	water	563:567	water	563:567	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	10	145	theme	prediction	2117:2126	arg1	accuracy					2128:2135	the %CY traits prediction accuracy	2102:2135	the %CY traits prediction accuracy	2102:2135	Finally, a stratified CrV (SCrV) was adopted to assess the %CY traits prediction accuracy across goat breeds, again using the best model, in which 5 breeds were included in CAL and the remaining one in the VAL set.					
35570042	0	146	theme	different	24:32	arg1	measures					34:41	different measures	24:41	different measures of cheese	24:51	Predictive formulas for different measures of cheese yield using milk composition from individual goat samples.					
35570042	7	147	theme	CrV	1464:1466	arg1	scheme					1469:1474	a cross-validation (CrV) scheme	1444:1474	a cross-validation (CrV) scheme	1444:1474	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	3	148	theme	CY	698:699	arg1	traits					701:706	The %CY traits	693:706	The %CY traits	693:706	The %CY traits were analyzed in duplicate from 600 goats, using an individual laboratory cheese-making procedure (9-MilCA method; 9 mL of milk per observation) for a total of 1,200 observations.					
35570042	5	149	used	used	1127:1130	arg2	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	CYCURD					1045:1050	%CYCURD	1044:1050	%CYCURD	1044:1050	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	CYSOLIDS					1069:1076	%CYSOLIDS	1068:1076	%CYSOLIDS	1068:1076	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	149	used	used	1127:1130	arg2	CYWATER					1101:1107	%CYWATER	1100:1107	%CYWATER	1100:1107	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	2	150	theme	%	679:679	arg1	formulas					683:690	the %CY formulas	675:690	the %CY formulas	675:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	12	151	theme	%	2483:2483	arg1	traits					2487:2492	all %CY traits	2479:2492	all %CY traits	2479:2492	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	1	152	theme	fresh	259:263	arg1	traits					251:256	cheese yield (%CY) traits	232:256	cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	232:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	152	theme	fresh	259:263	arg1	curd					265:268	fresh curd	259:268	fresh curd	259:268	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	7	153	theme	cross-validation	1446:1461	arg1	scheme					1469:1474	a cross-validation (CrV) scheme	1444:1474	a cross-validation (CrV) scheme	1444:1474	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	15	154	theme	milk	2957:2960	arg1	composition					2962:2972	milk composition	2957:2972	milk composition	2957:2972	These results may be useful to monitor milk composition and quantify the influence of milk traits in the composite selection indices of specific breeds, and for the direct genetic improvement of cheese production.					
35570042	14	155	theme	%	2893:2893	arg1	formulas					2908:2915	%CY predictive formulas	2893:2915	%CY predictive formulas	2893:2915	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	12	156	theme	prediction	2455:2464	arg1	accuracy					2466:2473	the best prediction accuracy	2446:2473	the best prediction accuracy	2446:2473	In CrV, the formula with the best prediction accuracy for all %CY traits included fat, casein, and UHI (R2VAL = 0.65, 0.96, and 0.23 for %CYCURD, %CYSOLIDS, and %CYWATER, respectively).					
35570042	2	157	dep	assess	343:348	arg1	quantify					354:361	quantify	354:361	quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas	354:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	5	158	theme	total	1054:1058	arg1	CYSOLIDS					1069:1076	%CYSOLIDS	1068:1076	%CYSOLIDS	1068:1076	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	158	theme	total	1054:1058	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	158	theme	total	1054:1058	arg1	variables					1144:1152	response variables	1135:1152	response variables	1135:1152	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	158	theme	total	1054:1058	arg1	water					1084:1088	water retained (%CYWATER)	1084:1108	water retained (%CYWATER)	1084:1108	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	158	theme	total	1054:1058	arg1	solids					1060:1065	total solids	1054:1065	total solids (%CYSOLIDS)	1054:1077	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	4	159	dep	breeds	936:941	arg1	breeds					936:941	6 breeds	934:941	6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva)	934:1030	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	4	159	dep	breeds	936:941	arg1	Alpi					989:992	Alpi	989:992	Alpi	989:992	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	4	159	dep	breeds	936:941	arg1	Primitiva					1021:1029	Primitiva	1021:1029	Primitiva	1021:1029	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	4	159	dep	breeds	936:941	arg1	Murciano-Granadina					952:969	Murciano-Granadina	952:969	Murciano-Granadina	952:969	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	4	159	dep	breeds	936:941	arg1	Maltese					995:1001	Maltese	995:1001	Maltese	995:1001	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	4	159	dep	breeds	936:941	arg1	Sarda					1004:1008	Sarda	1004:1008	Sarda	1004:1008	Goats were reared in 36 herds and belonged to 6 breeds (Saanen, Murciano-Granadina, Camosciata delle Alpi, Maltese, Sarda, and Sarda Primitiva).					
35570042	9	160	used	used	1780:1783	arg2	model					1693:1697	the model	1689:1697	the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula)	1689:1774	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	2	161	theme	cheese-making	600:612	arg1	method					614:619	the cheese-making method	596:619	(2) the cheese-making method	592:619	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	162	dep	effects	641:647	arg1	3					627:627	3	627:627	3	627:627	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	2	163	dep	indicators	453:462	arg1	lactose					465:471	lactose	465:471	lactose	465:471	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	14	164	theme	predictive	2897:2906	arg1	formulas					2908:2915	%CY predictive formulas	2893:2915	%CY predictive formulas	2893:2915	In the SCrV, large differences for %CYCURD and %CYWATER among breeds evidenced that the breed is a fundamental factor to consider in %CY predictive formulas.					
35570042	7	165	theme	CY	1395:1396	arg1	observations					1398:1409	The 2 %CY observations	1388:1409	The 2 %CY observations within animal	1388:1423	The 2 %CY observations within animal were averaged, and a cross-validation (CrV) scheme was adopted, in which 80% of observations were randomly assigned to the calibration (CAL) set and 20% to the validation (VAL) set.					
35570042	5	166	from	water	1084:1088	arg1	curd					1117:1120	the curd	1113:1120	the curd	1113:1120	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	9	167	theme	comprehensive	1753:1765	arg1	formula					1767:1773	comprehensive formula	1753:1773	comprehensive formula	1753:1773	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	9	167	theme	comprehensive	1753:1765	arg1	CrV					1742:1744	CrV	1742:1744	CrV (i.e., comprehensive formula)	1742:1774	Further, the model presenting the best prediction accuracy in CrV (i.e., comprehensive formula) was used in a secondary analysis to assess the accuracy of the %CY predictive formulas as part of the laboratory cheese-making procedure (within-animal validation, WAV), in which the first %CY observation within animal was assigned to CAL, and the second to the VAL set.					
35570042	2	168	theme	goat	630:633	arg1	effects					641:647	(3) goat breed effects	626:647	(3) goat breed effects on prediction accuracy of the %CY formulas	626:690	The specific aims were to assess and quantify (1) the contribution of major milk components (fat, protein, and casein) and udder health indicators (lactose, somatic cell count, pH, and bacterial count) on %CY traits (fresh curd, milk solids, and water retained in the curd); (2) the cheese-making method; and (3) goat breed effects on prediction accuracy of the %CY formulas.					
35570042	5	169	theme	%	1044:1044	arg1	CY					1040:1041	Fresh %CY	1033:1041	Fresh %CY (%CYCURD)	1033:1051	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	5	169	theme	%	1044:1044	arg1	CYCURD					1045:1050	%CYCURD	1044:1050	%CYCURD	1044:1050	Fresh %CY (%CYCURD), total solids (%CYSOLIDS), and water retained (%CYWATER) in the curd were used as response variables.					
35570042	1	170	theme	cheese	232:237	arg1	yield					239:243	cheese yield	232:243	cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd)	232:314	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
35570042	1	170	theme	cheese	232:237	arg1	CY					247:248	%CY	246:248	%CY	246:248	The objective of this study was to develop formulas based on milk composition of individual goat samples for predicting cheese yield (%CY) traits (fresh curd, milk solids, and water retained in the curd).					
36547866	5	0	theme	nitrogen	789:796	arg1	sources					798:804	additional nitrogen sources	778:804	additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds	778:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	9	1	theme	colloidal	1606:1614	arg1	chitin					1616:1621	colloidal chitin	1606:1621	colloidal chitin	1606:1621	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	5	2	theme	carbon	695:700	arg1	sources					702:708	The best carbon sources	686:708	The best carbon sources	686:708	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	2	theme	carbon	695:700	arg1	powder					715:720	powder	715:720	powder	715:720	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	3	theme	mealworms	736:744	arg1	molting					725:731	molting	725:731	molting of mealworms (MMP)	725:750	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	1	4	theme	Hermetia	151:158	arg1	insects					142:148	rotten insects	135:148	rotten insects (Hermetia illucens)	135:168	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	1	4	theme	Hermetia	151:158	arg1	illucens					160:167	Hermetia illucens	151:167	Hermetia illucens	151:167	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	8	5	theme	shells	1380:1385	arg1	MMP					1351:1353	MMP	1351:1353	MMP	1351:1353	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	5	theme	shells	1380:1385	arg1	powder					1363:1368	the powder	1359:1368	the powder of shrimp shells (SSP)	1359:1391	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	5	theme	shells	1380:1385	arg1	chitin					1343:1348	colloidal chitin	1333:1348	colloidal chitin	1333:1348	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	5	theme	shells	1380:1385	arg1	SSP					1388:1390	SSP	1388:1390	SSP	1388:1390	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	0	6	theme	chitinolytic	75:86	arg1	enzymes					88:94	chitinolytic enzymes	75:94	chitinolytic enzymes from two Talaromyces sp	75:118	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	3	7	from	fly	428:430	arg1	Hi-4					364:367	allahabadensis Hi-4	349:367	allahabadensis Hi-4	349:367	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	7	from	fly	428:430	arg1	Talaromyces					337:347	two fungi Talaromyces	327:347	two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly	327:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	7	from	fly	428:430	arg1	Hi-5					397:400	Talaromyces funiculosus Hi-5	373:400	Talaromyces funiculosus Hi-5	373:400	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	6	8	theme	colloidal	995:1003	arg1	chitin					987:992	Pure chitin	982:992	Pure chitin (colloidal chitin)	982:1011	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	6	8	theme	colloidal	995:1003	arg1	chitin					1005:1010	colloidal chitin	995:1010	colloidal chitin	995:1010	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	9	9	from	amounts	1459:1465	arg1	MMP					1507:1509	MMP	1507:1509	MMP	1507:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	9	from	amounts	1459:1465	arg1	SSP					1499:1501	SSP	1499:1501	SSP	1499:1501	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	5	10	theme	surface	967:973	arg1	plots					975:979	the 3D response surface plots	951:979	the 3D response surface plots	951:979	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	3	11	theme	Talaromyces	373:383	arg1	Talaromyces					337:347	two fungi Talaromyces	327:347	two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly	327:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	11	theme	Talaromyces	373:383	arg1	Hi-5					397:400	Talaromyces funiculosus Hi-5	373:400	Talaromyces funiculosus Hi-5	373:400	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	9	12	theme	chitin	1470:1475	arg1	oligosaccharides					1477:1492	chitin oligosaccharides	1470:1492	chitin oligosaccharides from SSP and MMP	1470:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	5	13	theme	Hi-5	909:912	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	13	theme	Hi-5	909:912	arg1	U/gds					915:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	9	14	from	1/17	1534:1537	arg1	comparison					1592:1601	comparison	1592:1601	comparison to colloidal chitin	1592:1621	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	3	15	theme	allahabadensis	349:362	arg1	Hi-4					364:367	allahabadensis Hi-4	349:367	allahabadensis Hi-4	349:367	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	15	theme	allahabadensis	349:362	arg1	Talaromyces					337:347	two fungi Talaromyces	327:347	two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly	327:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	10	16	theme	polymerization	1756:1769	arg1	degree					1746:1751	higher degree	1739:1751	higher degree of polymerization (4-6)	1739:1775	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	2	17	theme	chitinous	286:294	arg1	waste					296:300	untreated natural chitinous waste	268:300	untreated natural chitinous waste	268:300	It is difficult to produce chitin oligosaccharides by hydrolyzing untreated natural chitinous waste directly.					
36547866	10	18	with	oligosaccharides	1717:1732	arg1	degree					1746:1751	higher degree	1739:1751	higher degree of polymerization (4-6)	1739:1775	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	0	19	theme	Talaromyces	105:115	arg1	sp					117:118	two Talaromyces sp	101:118	two Talaromyces sp	101:118	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	4	20	theme	chitinolytic	524:535	arg1	enzymes					537:543	The chitinolytic enzymes	520:543	The chitinolytic enzymes	520:543	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36547866	2	21	theme	natural	278:284	arg1	waste					296:300	untreated natural chitinous waste	268:300	untreated natural chitinous waste	268:300	It is difficult to produce chitin oligosaccharides by hydrolyzing untreated natural chitinous waste directly.					
36547866	7	22	theme	optimum	1161:1167	arg1	lower					1232:1236	lower	1232:1236	lower	1232:1236	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	7	22	theme	optimum	1161:1167	arg1	temperature					1169:1179	The optimum temperature	1157:1179	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi)	1157:1225	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	10	23	from	applications	1838:1849	arg1	medicine					1854:1861	medicine	1854:1861	medicine	1854:1861	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	10	23	from	applications	1838:1849	arg1	products					1874:1881	health products	1867:1881	health products	1867:1881	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	1	24	theme	solid	176:180	arg1	fermentation					188:199	solid state fermentation	176:199	solid state fermentation	176:199	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	3	25	theme	rotten	407:412	arg1	fly					428:430	rotten black soldier fly	407:430	rotten black soldier fly	407:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	6	26	theme	Pure	982:985	arg1	chitin					987:992	Pure chitin	982:992	Pure chitin (colloidal chitin)	982:1011	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	6	26	theme	Pure	982:985	arg1	chitin					1005:1010	colloidal chitin	995:1010	colloidal chitin	995:1010	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	5	27	theme	best	690:693	arg1	sources					702:708	The best carbon sources	686:708	The best carbon sources	686:708	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	27	theme	best	690:693	arg1	powder					715:720	powder	715:720	powder	715:720	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	10	28	theme	main	1628:1631	arg1	GlcNAc					1665:1670	GlcNAc	1665:1670	GlcNAc for colloidal chitin, (GlcNAc)2 for MMP	1665:1710	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	10	28	theme	main	1628:1631	arg1	components					1633:1642	The main components	1624:1642	The main components of the products	1624:1658	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	1	29	theme	state	182:186	arg1	fermentation					188:199	solid state fermentation	176:199	solid state fermentation	176:199	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	0	30	theme	degrading	17:25	arg1	chitinous					35:43	degrading natural chitinous	17:43	degrading natural chitinous	17:43	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	6	31	used	used	1072:1075	arg2	chitin					987:992	Pure chitin	982:992	Pure chitin (colloidal chitin)	982:1011	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	6	31	used	used	1072:1075	arg2	chitin					1005:1010	colloidal chitin	995:1010	colloidal chitin	995:1010	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	6	31	used	used	1072:1075	arg2	substrates					1035:1044	natural chitinous substrates	1017:1044	natural chitinous substrates (represented by MMP)	1017:1065	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	5	32	theme	3D	955:956	arg1	plots					975:979	the 3D response surface plots	951:979	the 3D response surface plots	951:979	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	33	theme	enzyme	850:855	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	33	theme	enzyme	850:855	arg1	production					857:866	the maximum chitinolytic enzyme production	825:866	the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4)	825:889	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	34	theme	chitinolytic	837:848	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	34	theme	chitinolytic	837:848	arg1	production					857:866	the maximum chitinolytic enzyme production	825:866	the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4)	825:889	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	9	35	theme	oligosaccharides	1477:1492	arg1	oligosaccharides					1477:1492	chitin oligosaccharides	1470:1492	chitin oligosaccharides from SSP and MMP	1470:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	35	theme	oligosaccharides	1477:1492	arg1	1/17					1534:1537	1/17	1534:1537	1/17	1534:1537	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	35	theme	oligosaccharides	1477:1492	arg1	amounts					1459:1465	The amounts	1455:1465	The amounts of chitin oligosaccharides from SSP and MMP	1455:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	5	36	theme	response	958:965	arg1	plots					975:979	the 3D response surface plots	951:979	the 3D response surface plots	951:979	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	3	37	theme	morphological	496:508	arg1	analyses					510:517	multigene phylogenetic and morphological analyses	469:517	multigene phylogenetic and morphological analyses	469:517	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	0	38	theme	chitinous	35:43	arg1	potential					4:12	The potential	0:12	The potential of degrading natural chitinous	0:43	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	4	39	theme	growth	596:601	arg1	conditions					603:612	the growth conditions	592:612	the growth conditions	592:612	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36547866	7	40	theme	hydrolyzing	1185:1195	arg1	MMP					1197:1199	hydrolyzing MMP	1185:1199	hydrolyzing MMP (40 °C both in two fungi)	1185:1225	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	2	41	theme	chitin	229:234	arg1	oligosaccharides					236:251	chitin oligosaccharides	229:251	chitin oligosaccharides	229:251	It is difficult to produce chitin oligosaccharides by hydrolyzing untreated natural chitinous waste directly.					
36547866	3	42	theme	multigene	469:477	arg1	analyses					510:517	multigene phylogenetic and morphological analyses	469:517	multigene phylogenetic and morphological analyses	469:517	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	0	43	theme	natural	27:33	arg1	chitinous					35:43	degrading natural chitinous	17:43	degrading natural chitinous	17:43	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	4	44	theme	state	568:572	arg1	fermentation					574:585	solid state fermentation	562:585	solid state fermentation	562:585	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36547866	3	45	dep	Talaromyces	337:347	arg1	Hi-4					364:367	allahabadensis Hi-4	349:367	allahabadensis Hi-4	349:367	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	45	dep	Talaromyces	337:347	arg1	Talaromyces					337:347	two fungi Talaromyces	327:347	two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly	327:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	45	dep	Talaromyces	337:347	arg1	Hi-5					397:400	Talaromyces funiculosus Hi-5	373:400	Talaromyces funiculosus Hi-5	373:400	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	5	46	theme	maximum	829:835	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	46	theme	maximum	829:835	arg1	production					857:866	the maximum chitinolytic enzyme production	825:866	the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4)	825:889	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	3	47	theme	phylogenetic	479:490	arg1	analyses					510:517	multigene phylogenetic and morphological analyses	469:517	multigene phylogenetic and morphological analyses	469:517	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	48	theme	black	414:418	arg1	fly					428:430	rotten black soldier fly	407:430	rotten black soldier fly	407:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	4	49	theme	solid	562:566	arg1	fermentation					574:585	solid state fermentation	562:585	solid state fermentation	562:585	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36547866	3	50	theme	soldier	420:426	arg1	fly					428:430	rotten black soldier fly	407:430	rotten black soldier fly	407:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	5	51	theme	molting	725:731	arg1	sources					702:708	The best carbon sources	686:708	The best carbon sources	686:708	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	51	theme	molting	725:731	arg1	powder					715:720	powder	715:720	powder	715:720	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	0	52	from	sp	117:118	arg1	enzymes					88:94	chitinolytic enzymes	75:94	chitinolytic enzymes from two Talaromyces sp	75:118	The potential of degrading natural chitinous wastes to oligosaccharides by chitinolytic enzymes from two Talaromyces sp.					
36547866	7	53	theme	room	1252:1255	arg1	temperature					1257:1267	room temperature	1252:1267	room temperature	1252:1267	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	9	54	from	MMP	1507:1509	arg1	oligosaccharides					1477:1492	chitin oligosaccharides	1470:1492	chitin oligosaccharides from SSP and MMP	1470:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	54	from	MMP	1507:1509	arg1	1/17					1534:1537	1/17	1534:1537	1/17	1534:1537	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	54	from	MMP	1507:1509	arg1	amounts					1459:1465	The amounts	1455:1465	The amounts of chitin oligosaccharides from SSP and MMP	1455:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	8	55	used	used	1398:1401	arg2	chitin					1343:1348	colloidal chitin	1333:1348	colloidal chitin	1333:1348	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	55	used	used	1398:1401	arg2	powder					1363:1368	the powder	1359:1368	the powder of shrimp shells (SSP)	1359:1391	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	55	used	used	1398:1401	arg2	SSP					1388:1390	SSP	1388:1390	SSP	1388:1390	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	8	55	used	used	1398:1401	arg2	MMP					1351:1353	MMP	1351:1353	MMP	1351:1353	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	7	56	dep	MMP	1197:1199	arg1	both					1208:1211	both	1208:1211	both	1208:1211	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	5	57	from	sources	798:804	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	57	from	sources	798:804	arg1	production					857:866	the maximum chitinolytic enzyme production	825:866	the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4)	825:889	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	57	from	sources	798:804	arg1	U/gds					915:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	2	58	theme	untreated	268:276	arg1	waste					296:300	untreated natural chitinous waste	268:300	untreated natural chitinous waste	268:300	It is difficult to produce chitin oligosaccharides by hydrolyzing untreated natural chitinous waste directly.					
36547866	10	59	theme	products	1651:1658	arg1	GlcNAc					1665:1670	GlcNAc	1665:1670	GlcNAc for colloidal chitin, (GlcNAc)2 for MMP	1665:1710	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	10	59	theme	products	1651:1658	arg1	components					1633:1642	The main components	1624:1642	The main components of the products	1624:1658	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	6	60	theme	crude	1114:1118	arg1	enzymes					1120:1126	crude enzymes	1114:1126	crude enzymes obtained from the two fungi	1114:1154	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	8	61	theme	colloidal	1333:1341	arg1	chitin					1343:1348	colloidal chitin	1333:1348	colloidal chitin	1333:1348	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	6	62	theme	chitinous	1025:1033	arg1	substrates					1035:1044	natural chitinous substrates	1017:1044	natural chitinous substrates (represented by MMP)	1017:1065	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	3	63	dep	Talaromyces	373:383	arg1	funiculosus					385:395	funiculosus	385:395	funiculosus	385:395	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	10	64	theme	colloidal	1676:1684	arg1	GlcNAc					1695:1700	(GlcNAc)2	1694:1702	(GlcNAc)2 for MMP	1694:1710	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	10	64	theme	colloidal	1676:1684	arg1	chitin					1686:1691	colloidal chitin	1676:1691	colloidal chitin	1676:1691	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	1	65	theme	rotten	135:140	arg1	insects					142:148	rotten insects	135:148	rotten insects (Hermetia illucens)	135:168	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	1	65	theme	rotten	135:140	arg1	illucens					160:167	Hermetia illucens	151:167	Hermetia illucens	151:167	isolated from rotten insects (Hermetia illucens) under solid state fermentation.					
36547866	9	66	from	SSP	1499:1501	arg1	oligosaccharides					1477:1492	chitin oligosaccharides	1470:1492	chitin oligosaccharides from SSP and MMP	1470:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	66	from	SSP	1499:1501	arg1	1/17					1534:1537	1/17	1534:1537	1/17	1534:1537	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	9	66	from	SSP	1499:1501	arg1	amounts					1459:1465	The amounts	1455:1465	The amounts of chitin oligosaccharides from SSP and MMP	1455:1509	The amounts of chitin oligosaccharides from SSP and MMP were about 1/6 (Hi-4), 1/17 (Hi-5) and 1/8 (Hi-4), 1/10 (Hi-5), respectively, in comparison to colloidal chitin.					
36547866	6	67	theme	natural	1017:1023	arg1	substrates					1035:1044	natural chitinous substrates	1017:1044	natural chitinous substrates (represented by MMP)	1017:1065	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	3	68	theme	fungi	331:335	arg1	Hi-4					364:367	allahabadensis Hi-4	349:367	allahabadensis Hi-4	349:367	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	68	theme	fungi	331:335	arg1	Talaromyces					337:347	two fungi Talaromyces	327:347	two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly	327:430	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	3	68	theme	fungi	331:335	arg1	Hi-5					397:400	Talaromyces funiculosus Hi-5	373:400	Talaromyces funiculosus Hi-5	373:400	In this study, two fungi Talaromyces allahabadensis Hi-4 and Talaromyces funiculosus Hi-5 from rotten black soldier fly were isolated and identified through multigene phylogenetic and morphological analyses.					
36547866	5	69	theme	46.80 ± 3.30	871:882	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	69	theme	46.80 ± 3.30	871:882	arg1	production					857:866	the maximum chitinolytic enzyme production	825:866	the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4)	825:889	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	69	theme	46.80 ± 3.30	871:882	arg1	U/gds					915:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	8	70	theme	shrimp	1373:1378	arg1	shells					1380:1385	shrimp shells	1373:1385	shrimp shells	1373:1385	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	7	71	theme	colloidal	1274:1282	arg1	chitin					1284:1289	colloidal chitin	1274:1289	colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5)	1274:1325	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	5	72	theme	55.07 ± 2.48	895:906	arg1	fungi					813:817	two fungi	809:817	two fungi	809:817	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	5	72	theme	55.07 ± 2.48	895:906	arg1	U/gds					915:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	55.07 ± 2.48 (Hi-5) U/gds	895:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	10	73	theme	health	1867:1872	arg1	products					1874:1881	health products	1867:1881	health products	1867:1881	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	4	74	theme	composite	668:676	arg1	design					678:683	central composite design	660:683	central composite design	660:683	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36547866	5	75	theme	additional	778:787	arg1	sources					798:804	additional nitrogen sources	778:804	additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds	778:919	The best carbon sources were powder of molting of mealworms (MMP) and there was no need for additional nitrogen sources in two fungi, then the maximum chitinolytic enzyme production of 46.80 ± 3.30 (Hi-4) and 55.07 ± 2.48 (Hi-5) U/gds were achieved after analyzing the 3D response surface plots.					
36547866	10	76	theme	higher	1739:1744	arg1	degree					1746:1751	higher degree	1739:1751	higher degree of polymerization (4-6)	1739:1775	The main components of the products were GlcNAc for colloidal chitin, (GlcNAc)2 for MMP, and oligosaccharides with higher degree of polymerization (4-6) were obtained when hydrolyzing SSP, which is significant for applications in medicine and health products.					
36547866	7	77	dep	chitin	1284:1289	arg1	55 °C					1292:1296	55 °C	1292:1296	55 °C	1292:1296	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	7	77	dep	chitin	1284:1289	arg1	45 °C					1311:1315	45 °C	1311:1315	45 °C	1311:1315	The optimum temperature for hydrolyzing MMP (40 °C both in two fungi) were lower and closer to room temperature than colloidal chitin (55 °C for Hi-4 and 45 °C for Hi-5).					
36547866	6	78	theme	degradation	1089:1099	arg1	abilities					1101:1109	degradation abilities	1089:1109	degradation abilities	1089:1109	Pure chitin (colloidal chitin) and natural chitinous substrates (represented by MMP) were used to optimize degradation abilities by crude enzymes obtained from the two fungi.					
36547866	8	79	theme	5-day	1436:1440	arg1	degradation					1442:1452	5-day degradation	1436:1452	5-day degradation	1436:1452	Then colloidal chitin, MMP and the powder of shrimp shells (SSP) were used for analyzing the products after 5-day degradation.					
36547866	4	80	theme	central	660:666	arg1	design					678:683	central composite design	660:683	central composite design	660:683	The chitinolytic enzymes were produced by solid state fermentation, and the growth conditions were optimized by combining single-factor and central composite design.					
36296474	4	0	theme	investigations	321:334	arg1	series					297:302	A series	295:302	A series of comprehensive investigations on its chemical constituents and bioactivities	295:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	11	1	theme	antioxidant	1237:1247	arg1	activity					1249:1256	prominent antioxidant activity	1227:1256	prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods	1227:1300	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	9	2	theme	%	873:873	arg1	±					867:867	9.41 ±	862:867	9.41 ± 0.03%	862:873	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	2	3	theme	tikoua	163:168	arg1	Bur					170:172	Ficus tikoua Bur	157:172	Ficus tikoua Bur	157:172	Although the fruit of Ficus tikoua Bur.					
36296474	13	4	theme	functional	1790:1799	arg1	food					1801:1804	functional food	1790:1804	functional food	1790:1804	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	3	5	theme	chemical	240:247	arg1	composition					264:274	its chemical and biological composition	236:274	its chemical and biological composition	236:274	has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear.					
36296474	4	6	theme	first	408:412	arg1	time					414:417	the first time	404:417	the first time	404:417	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	11	7	theme	ABTS	1272:1275	arg1	methods					1294:1300	ABTS, DPPH, and FRAPS methods	1272:1300	ABTS, DPPH, and FRAPS methods	1272:1300	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	13	8	theme	tikoua	1759:1764	arg1	fruit					1747:1751	the fruit	1743:1751	the fruit of F. tikoua	1743:1764	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	13	8	theme	tikoua	1759:1764	arg1	source					1780:1785	a reliable source	1769:1785	a reliable source of functional food	1769:1804	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	3	9	dep	China	215:219	arg1	unclear					286:292	unclear	286:292	unclear	286:292	has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear.					
36296474	8	10	theme	fatty	700:704	arg1	acids					706:710	The fatty acids	696:710	The fatty acids	696:710	The fatty acids are mainly composed of linolenic acid (61.27%) and linoleic acid (22.79%).					
36296474	12	11	from	expression	1504:1513	arg1	cytoplasm					1548:1556	the cytoplasm	1544:1556	the cytoplasm	1544:1556	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	6	12	theme	tikoua	577:582	arg1	Bur					584:586	that Ficus tikoua Bur	566:586	that Ficus tikoua Bur	566:586	GC-MS analysis of the lipid components demonstrated that Ficus tikoua Bur.					
36296474	3	13	theme	biological	253:262	arg1	composition					264:274	its chemical and biological composition	236:274	its chemical and biological composition	236:274	has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear.					
36296474	9	14	theme	0.03	869:872	arg1	%					873:873	%	873:873	%	873:873	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	11	15	theme	flavonoid	1198:1206	arg1	extracts					1208:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	8	16	theme	linolenic	735:743	arg1	acid					745:748	linolenic acid	735:748	linolenic acid (61.27%)	735:757	The fatty acids are mainly composed of linolenic acid (61.27%) and linoleic acid (22.79%).					
36296474	8	16	theme	linolenic	735:743	arg1	%					756:756	61.27%	751:756	61.27%	751:756	The fatty acids are mainly composed of linolenic acid (61.27%) and linoleic acid (22.79%).					
36296474	9	17	theme	total	908:912	arg1	polyphenols					914:924	total polyphenols	908:924	total polyphenols (0.86 ± 0.01 g/100 g)	908:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	9	17	theme	total	908:912	arg1	g					945:945	0.86 ± 0.01 g/100 g	927:945	0.86 ± 0.01 g/100 g	927:945	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	3	18	from	people	205:210	arg1	China					215:219	China	215:219	China	215:219	has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear.					
36296474	12	19	theme	c-Jun	1591:1595	arg1	translocation					1574:1586	the translocation	1570:1586	the translocation of c-Jun and p65 to the nucleus	1570:1618	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	13	20	theme	F.	1756:1757	arg1	tikoua					1759:1764	F. tikoua	1756:1764	F. tikoua	1756:1764	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	7	21	theme	fatty	640:644	arg1	acids					646:650	fatty acids	640:650	fatty acids	640:650	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	11	22	theme	DPPH	1278:1281	arg1	methods					1294:1300	ABTS, DPPH, and FRAPS methods	1272:1300	ABTS, DPPH, and FRAPS methods	1272:1300	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	12	23	dep	enhancing	1388:1396	arg1	decreasing					1489:1498	decreasing	1489:1498	significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm	1475:1556	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	4	24	from	constituents	352:363	arg1	series					297:302	A series	295:302	A series of comprehensive investigations on its chemical constituents and bioactivities	295:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	7	25	theme	wholesome	609:617	arg1	constituents					619:630	some wholesome constituents	604:630	some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols	604:693	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	25	theme	wholesome	609:617	arg1	phytosterols					682:693	phytosterols	682:693	phytosterols	682:693	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	25	theme	wholesome	609:617	arg1	vitamins					653:660	vitamins	653:660	vitamins	653:660	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	25	theme	wholesome	609:617	arg1	triterpenoids					663:675	triterpenoids	663:675	triterpenoids	663:675	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	25	theme	wholesome	609:617	arg1	acids					646:650	fatty acids	640:650	fatty acids	640:650	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	12	26	theme	p65	1528:1530	arg1	proteins					1532:1539	p65 proteins	1528:1539	p65 proteins	1528:1539	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	11	27	theme	polyphenol	1166:1175	arg1	extracts					1208:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	11	28	theme	polysaccharide	1150:1163	arg1	extracts					1208:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	0	29	theme	Systematical	0:11	arg1	Investigations					24:37	Systematical Ingredient Investigations	0:37	Systematical Ingredient Investigations of Ficus tikoua	0:53	Systematical Ingredient Investigations of Ficus tikoua Bur.					
36296474	10	30	theme	total	1008:1012	arg1	polysaccharide					1014:1027	the total polysaccharide	1004:1027	the total polysaccharide	1004:1027	The analysis of monosaccharide composition showed that the total polysaccharide mainly consists of glucose, glucuronic acid, xylose, arabinose, mannose, galactose, galacturonic acid, and rhamnose.					
36296474	12	31	theme	PI3K/AKT	1692:1699	arg1	pathway					1711:1717	the PI3K/AKT signaling pathway	1688:1717	the PI3K/AKT signaling pathway	1688:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	1	32	theme	Different	114:122	arg1	Fractions					124:132	Different Fractions	114:132	Different Fractions	114:132	Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions.					
36296474	12	33	theme	c-Jun	1518:1522	arg1	expression					1504:1513	the expression	1500:1513	the expression of c-Jun and p65 proteins in the cytoplasm	1500:1556	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	0	34	theme	Ficus	42:46	arg1	tikoua					48:53	Ficus tikoua	42:53	Ficus tikoua	42:53	Systematical Ingredient Investigations of Ficus tikoua Bur.					
36296474	0	35	dep	Bur	55:57	arg1	Investigations					24:37	Systematical Ingredient Investigations	0:37	Systematical Ingredient Investigations of Ficus tikoua	0:53	Systematical Ingredient Investigations of Ficus tikoua Bur.					
36296474	4	36	theme	chemical	343:350	arg1	constituents					352:363	its chemical constituents	339:363	its chemical constituents	339:363	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	9	37	theme	high	831:834	arg1	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	2	38	theme	Bur	170:172	arg1	fruit					148:152	the fruit	144:152	the fruit of Ficus tikoua Bur	144:172	Although the fruit of Ficus tikoua Bur.					
36296474	7	39	contain	contains	595:602	arg2	triterpenoids					663:675	triterpenoids	663:675	triterpenoids	663:675	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	39	contain	contains	595:602	arg2	acids					646:650	fatty acids	640:650	fatty acids	640:650	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	39	contain	contains	595:602	arg2	phytosterols					682:693	phytosterols	682:693	phytosterols	682:693	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	39	contain	contains	595:602	arg1	fruit					589:593	fruit	589:593	fruit	589:593	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	39	contain	contains	595:602	arg2	constituents					619:630	some wholesome constituents	604:630	some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols	604:693	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	7	39	contain	contains	595:602	arg2	vitamins					653:660	vitamins	653:660	vitamins	653:660	fruit contains some wholesome constituents such as fatty acids, vitamins, triterpenoids, and phytosterols.					
36296474	12	40	theme	significant	1349:1359	arg1	effect					1378:1383	significant immunomodulatory effect	1349:1383	significant immunomodulatory effect	1349:1383	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	41	theme	phosphorylation	1640:1654	arg1	level					1656:1660	the phosphorylation level	1636:1660	the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway	1636:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	9	42	theme	protein	853:859	arg1	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	9	43	theme	total	877:881	arg1	acids					889:893	total amino acids	877:893	total amino acids (9.28%)	877:901	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	9	43	theme	total	877:881	arg1	%					900:900	9.28%	896:900	9.28%	896:900	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	11	44	theme	prominent	1227:1235	arg1	activity					1249:1256	prominent antioxidant activity	1227:1256	prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods	1227:1300	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	6	45	theme	GC-MS	514:518	arg1	analysis					520:527	GC-MS analysis	514:527	GC-MS analysis of the lipid components	514:551	GC-MS analysis of the lipid components demonstrated that Ficus tikoua Bur.					
36296474	6	46	theme	components	542:551	arg1	analysis					520:527	GC-MS analysis	514:527	GC-MS analysis of the lipid components	514:551	GC-MS analysis of the lipid components demonstrated that Ficus tikoua Bur.					
36296474	2	47	theme	Ficus	157:161	arg1	Bur					170:172	Ficus tikoua Bur	157:172	Ficus tikoua Bur	157:172	Although the fruit of Ficus tikoua Bur.					
36296474	13	48	theme	food	1801:1804	arg1	fruit					1747:1751	the fruit	1743:1751	the fruit of F. tikoua	1743:1764	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	13	48	theme	food	1801:1804	arg1	source					1780:1785	a reliable source	1769:1785	a reliable source of functional food	1769:1804	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	5	49	theme	main	483:486	arg1	compounds					437:445	six compounds	433:445	six compounds	433:445	As a result, six compounds were isolated and identified as the main components in this fruit.					
36296474	5	49	theme	main	483:486	arg1	components					488:497	the main components	479:497	the main components in this fruit	479:511	As a result, six compounds were isolated and identified as the main components in this fruit.					
36296474	12	50	theme	p65	1601:1603	arg1	translocation					1574:1586	the translocation	1570:1586	the translocation of c-Jun and p65 to the nucleus	1570:1618	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	9	51	theme	amino	883:887	arg1	acids					889:893	total amino acids	877:893	total amino acids (9.28%)	877:901	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	9	51	theme	amino	883:887	arg1	%					900:900	9.28%	896:900	9.28%	896:900	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	11	52	theme	ethanol	1185:1191	arg1	extracts					1208:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	9	53	theme	acids	889:893	arg1	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	13	54	theme	reliable	1771:1778	arg1	fruit					1747:1751	the fruit	1743:1751	the fruit of F. tikoua	1743:1764	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	13	54	theme	reliable	1771:1778	arg1	source					1780:1785	a reliable source	1769:1785	a reliable source of functional food	1769:1804	This study proved that the fruit of F. tikoua is a reliable source of functional food.					
36296474	4	55	from	bioactivities	369:381	arg1	series					297:302	A series	295:302	A series of comprehensive investigations on its chemical constituents and bioactivities	295:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	6	56	theme	Ficus	571:575	arg1	Bur					584:586	that Ficus tikoua Bur	566:586	that Ficus tikoua Bur	566:586	GC-MS analysis of the lipid components demonstrated that Ficus tikoua Bur.					
36296474	12	57	theme	COX-2	1450:1454	arg1	expression					1427:1436	expression	1427:1436	expression of iNOS and COX-2 in RAW264.7 cells	1427:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	57	theme	COX-2	1450:1454	arg1	release					1402:1408	the release	1398:1408	the release of cytokines	1398:1421	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	11	58	theme	water	1178:1182	arg1	extracts					1208:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts	1146:1215	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	1	59	theme	Fractions	124:132	arg1	Effects					103:109	Immunoregulatory and Antioxidant Effects	70:109	Immunoregulatory and Antioxidant Effects of Different Fractions	70:132	Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions.					
36296474	1	59	theme	Fractions	124:132	arg1	Fruit					60:64	Fruit	60:64	Fruit	60:64	Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions.					
36296474	12	60	theme	RAW264.7	1459:1466	arg1	cells					1468:1472	RAW264.7 cells	1459:1472	RAW264.7 cells	1459:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	9	61	contain	contains	811:818	arg1	fruit					805:809	this fruit	800:809	this fruit	800:809	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	9	61	contain	contains	811:818	arg2	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	4	62	from	investigations	321:334	arg1	bioactivities					369:381	bioactivities	369:381	bioactivities	369:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	4	62	from	investigations	321:334	arg1	constituents					352:363	its chemical constituents	339:363	its chemical constituents	339:363	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	9	63	theme	polyphenols	914:924	arg1	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	12	64	theme	iNOS	1441:1444	arg1	expression					1427:1436	expression	1427:1436	expression of iNOS and COX-2 in RAW264.7 cells	1427:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	64	theme	iNOS	1441:1444	arg1	release					1402:1408	the release	1398:1408	the release of cytokines	1398:1421	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	10	65	theme	composition	980:990	arg1	analysis					953:960	The analysis	949:960	The analysis of monosaccharide composition	949:990	The analysis of monosaccharide composition showed that the total polysaccharide mainly consists of glucose, glucuronic acid, xylose, arabinose, mannose, galactose, galacturonic acid, and rhamnose.					
36296474	10	66	theme	galacturonic	1113:1124	arg1	acid					1126:1129	galacturonic acid	1113:1129	galacturonic acid	1113:1129	The analysis of monosaccharide composition showed that the total polysaccharide mainly consists of glucose, glucuronic acid, xylose, arabinose, mannose, galactose, galacturonic acid, and rhamnose.					
36296474	12	67	from	expression	1427:1436	arg1	cells					1468:1472	RAW264.7 cells	1459:1472	RAW264.7 cells	1459:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	68	theme	cytokines	1413:1421	arg1	expression					1427:1436	expression	1427:1436	expression of iNOS and COX-2 in RAW264.7 cells	1427:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	68	theme	cytokines	1413:1421	arg1	release					1402:1408	the release	1398:1408	the release of cytokines	1398:1421	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	4	69	theme	comprehensive	307:319	arg1	investigations					321:334	comprehensive investigations	307:334	comprehensive investigations on its chemical constituents and bioactivities	307:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	11	70	theme	FRAPS	1288:1292	arg1	methods					1294:1300	ABTS, DPPH, and FRAPS methods	1272:1300	ABTS, DPPH, and FRAPS methods	1272:1300	The polysaccharide, polyphenol, water, ethanol, and flavonoid extracts exhibited prominent antioxidant activity determined by ABTS, DPPH, and FRAPS methods.					
36296474	8	71	theme	linoleic	763:770	arg1	%					783:783	22.79%	778:783	22.79%	778:783	The fatty acids are mainly composed of linolenic acid (61.27%) and linoleic acid (22.79%).					
36296474	8	71	theme	linoleic	763:770	arg1	acid					772:775	linoleic acid	763:775	linoleic acid (22.79%)	763:784	The fatty acids are mainly composed of linolenic acid (61.27%) and linoleic acid (22.79%).					
36296474	10	72	theme	monosaccharide	965:978	arg1	composition					980:990	monosaccharide composition	965:990	monosaccharide composition	965:990	The analysis of monosaccharide composition showed that the total polysaccharide mainly consists of glucose, glucuronic acid, xylose, arabinose, mannose, galactose, galacturonic acid, and rhamnose.					
36296474	1	73	theme	Immunoregulatory	70:85	arg1	Effects					103:109	Immunoregulatory and Antioxidant Effects	70:109	Immunoregulatory and Antioxidant Effects of Different Fractions	70:132	Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions.					
36296474	4	74	from	series	297:302	arg1	bioactivities					369:381	bioactivities	369:381	bioactivities	369:381	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	4	74	from	series	297:302	arg1	constituents					352:363	its chemical constituents	339:363	its chemical constituents	339:363	A series of comprehensive investigations on its chemical constituents and bioactivities were carried out for the first time.					
36296474	3	75	theme	montanic	196:203	arg1	people					205:210	montanic people	196:210	montanic people in China for centuries, its chemical and biological composition was still unclear	196:292	has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear.					
36296474	0	76	theme	Ingredient	13:22	arg1	Investigations					24:37	Systematical Ingredient Investigations	0:37	Systematical Ingredient Investigations of Ficus tikoua	0:53	Systematical Ingredient Investigations of Ficus tikoua Bur.					
36296474	12	77	from	release	1402:1408	arg1	cells					1468:1472	RAW264.7 cells	1459:1472	RAW264.7 cells	1459:1472	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	6	78	theme	lipid	536:540	arg1	components					542:551	the lipid components	532:551	the lipid components	532:551	GC-MS analysis of the lipid components demonstrated that Ficus tikoua Bur.					
36296474	1	79	theme	Antioxidant	91:101	arg1	Effects					103:109	Immunoregulatory and Antioxidant Effects	70:109	Immunoregulatory and Antioxidant Effects of Different Fractions	70:132	Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions.					
36296474	12	80	theme	proteins	1532:1539	arg1	expression					1504:1513	the expression	1500:1513	the expression of c-Jun and p65 proteins in the cytoplasm	1500:1556	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	81	theme	signaling	1701:1709	arg1	pathway					1711:1717	the PI3K/AKT signaling pathway	1688:1717	the PI3K/AKT signaling pathway	1688:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	0	82	theme	tikoua	48:53	arg1	Investigations					24:37	Systematical Ingredient Investigations	0:37	Systematical Ingredient Investigations of Ficus tikoua	0:53	Systematical Ingredient Investigations of Ficus tikoua Bur.					
36296474	9	83	dep	protein	853:859	arg1	±					867:867	9.41 ±	862:867	9.41 ± 0.03%	862:873	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	12	84	theme	immunomodulatory	1361:1376	arg1	effect					1378:1383	significant immunomodulatory effect	1349:1383	significant immunomodulatory effect	1349:1383	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	9	85	theme	relative	822:829	arg1	content					836:842	a relative high content	820:842	a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g)	820:946	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	12	86	theme	PDK1	1680:1683	arg1	level					1656:1660	the phosphorylation level	1636:1660	the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway	1636:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	87	theme	Akt	1665:1667	arg1	level					1656:1660	the phosphorylation level	1636:1660	the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway	1636:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	88	theme	total	1318:1322	arg1	Meanwhile					1303:1311	Meanwhile	1303:1311	Meanwhile	1303:1311	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	12	88	theme	total	1318:1322	arg1	polysaccharide					1324:1337	the total polysaccharide	1314:1337	the total polysaccharide	1314:1337	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	5	89	from	components	488:497	arg1	fruit					507:511	this fruit	502:511	this fruit	502:511	As a result, six compounds were isolated and identified as the main components in this fruit.					
36296474	12	90	theme	PI3K	1670:1673	arg1	level					1656:1660	the phosphorylation level	1636:1660	the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway	1636:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	9	91	theme	crude	847:851	arg1	protein					853:859	crude protein	847:859	crude protein (9.41 ± 0.03%)	847:874	Furthermore, this fruit contains a relative high content of crude protein (9.41 ± 0.03%), total amino acids (9.28%), and total polyphenols (0.86 ± 0.01 g/100 g).					
36296474	12	92	from	level	1656:1660	arg1	pathway					1711:1717	the PI3K/AKT signaling pathway	1688:1717	the PI3K/AKT signaling pathway	1688:1717	Meanwhile, the total polysaccharide exhibited significant immunomodulatory effect by enhancing the release of cytokines and expression of iNOS and COX-2 in RAW264.7 cells, significantly decreasing the expression of c-Jun and p65 proteins in the cytoplasm; increasing the translocation of c-Jun and p65 to the nucleus; and regulating the phosphorylation level of Akt, PI3K, and PDK1 in the PI3K/AKT signaling pathway.					
36296474	10	93	theme	glucuronic	1057:1066	arg1	acid					1068:1071	glucuronic acid	1057:1071	glucuronic acid	1057:1071	The analysis of monosaccharide composition showed that the total polysaccharide mainly consists of glucose, glucuronic acid, xylose, arabinose, mannose, galactose, galacturonic acid, and rhamnose.					
36075306	4	0	theme	mouse	774:778	arg1	experiments					780:790	the mouse experiments	770:790	the mouse experiments	770:790	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	1	1	theme	glucose	117:123	arg1	glycogen					87:94	Liver glycogen	81:94	Liver glycogen	81:94	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	1	1	theme	glucose	117:123	arg1	polymer					125:131	a highly branched glucose polymer	99:131	a highly branched glucose polymer	99:131	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	3	2	with	humans	616:621	arg1	diabetes					628:635	diabetes	628:635	diabetes	628:635	Here we tested if this α-particle fragility also occurred in liver glycogen obtained from humans with diabetes.					
36075306	4	3	from	ran	795:797	arg1	parallel					802:809	parallel	802:809	parallel	802:809	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	0	4	theme	pilot	68:72	arg1	study					74:78	A pilot study	66:78	A pilot study	66:78	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	2	5	from	models	364:369	arg1	fragile					290:296	fragile	290:296	fragile	290:296	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	6	theme	disease	517:523	arg1	characteristic					495:508	the poor blood-sugar homeostasis characteristic	462:508	the poor blood-sugar homeostasis characteristic of the disease	462:523	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	7	dep	fragile	290:296	arg1	up					308:309	breaking up	299:309	breaking up into smaller particles in certain solvents	299:352	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	5	8	dep	groups	962:967	arg1	both					941:944	both	941:944	both	941:944	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	5	8	dep	groups	962:967	arg1	mouse					956:960	mouse	956:960	mouse	956:960	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	2	9	theme	glycogen	426:433	arg1	particles					435:443	the resulting small glycogen particles	406:443	the resulting small glycogen particles	406:443	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	4	10	theme	diabetic	676:683	arg1	humans					685:690	diabetic humans	676:690	diabetic humans	676:690	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	4	11	from	humans	685:690	arg1	glycogen					662:669	liver glycogen	656:669	liver glycogen from diabetic humans	656:690	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	0	12	dep	study	74:78	arg1	fragility					4:12	The fragility	0:12	The fragility of liver glycogen from humans with type 2 diabetes	0:63	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	1	13	theme	larger	205:210	arg1	particles					224:232	larger composite α particles	205:232	larger composite α particles	205:232	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	2	14	theme	small	420:424	arg1	particles					435:443	the resulting small glycogen particles	406:443	the resulting small glycogen particles	406:443	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	0	15	from	humans	37:42	arg1	fragility					4:12	The fragility	0:12	The fragility of liver glycogen from humans with type 2 diabetes	0:63	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	5	16	dep	both	941:944	arg1	human					946:950	human	946:950	human	946:950	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	4	17	theme	non-diabetic	726:737	arg1	humans					739:744	non-diabetic humans	726:744	non-diabetic humans	726:744	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	2	18	theme	resulting	410:418	arg1	particles					435:443	the resulting small glycogen particles	406:443	the resulting small glycogen particles	406:443	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	19	from	fragile	290:296	arg1	models					364:369	mouse models	358:369	mouse models of diabetes	358:381	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	5	20	theme	candidate	846:854	arg1	proteins					856:863	three candidate proteins	840:863	three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes)	840:936	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	2	21	theme	smaller	316:322	arg1	particles					324:332	smaller particles	316:332	smaller particles in certain solvents	316:352	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	4	22	theme	liver	656:660	arg1	glycogen					662:669	liver glycogen	656:669	liver glycogen from diabetic humans	656:690	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	6	23	from	different	1092:1100	arg1	glycogen					1114:1121	diabetic glycogen	1105:1121	diabetic glycogen	1105:1121	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	1	24	theme	β	142:142	arg1	particles					144:152	β particles	142:152	β particles (~20 nm in diameter)	142:173	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	1	25	theme	composite	212:220	arg1	particles					224:232	larger composite α particles	205:232	larger composite α particles	205:232	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	0	26	theme	liver	17:21	arg1	glycogen					23:30	liver glycogen	17:30	liver glycogen	17:30	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	2	27	theme	mouse	358:362	arg1	models					364:369	mouse models	358:369	mouse models of diabetes	358:381	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	1	28	theme	α	222:222	arg1	particles					224:232	larger composite α particles	205:232	larger composite α particles	205:232	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	2	29	theme	poor	466:469	arg1	characteristic					495:508	the poor blood-sugar homeostasis characteristic	462:508	the poor blood-sugar homeostasis characteristic of the disease	462:523	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	30	theme	α	243:243	arg1	particles					245:253	Hepatic α particles	235:253	Hepatic α particles	235:253	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	4	31	from	humans	739:744	arg1	ran					795:797	ran	795:797	ran	795:797	It was found that liver glycogen from diabetic humans was indeed more fragile than from non-diabetic humans, which was also seen in the mouse experiments we ran in parallel.					
36075306	2	32	theme	Hepatic	235:241	arg1	particles					245:253	Hepatic α particles	235:253	Hepatic α particles	235:253	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	33	theme	certain	337:343	arg1	solvents					345:352	certain solvents	337:352	certain solvents	337:352	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	0	34	theme	glycogen	23:30	arg1	fragility					4:12	The fragility	0:12	The fragility of liver glycogen from humans with type 2 diabetes	0:63	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	3	35	theme	α-particle	549:558	arg1	fragility					560:568	this α-particle fragility	544:568	this α-particle fragility	544:568	Here we tested if this α-particle fragility also occurred in liver glycogen obtained from humans with diabetes.					
36075306	1	36	dep	particles	144:152	arg1	~20 nm					155:160	~20 nm	155:160	~20 nm in diameter	155:172	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	6	37	from	glycogen	1114:1121	arg1	different					1092:1100	different	1092:1100	different	1092:1100	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	5	38	theme	glycogen	895:902	arg1	proteins					904:911	differentially expressed glycogen proteins	870:911	differentially expressed glycogen proteins (Diabetes/ Non-diabetes)	870:936	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	5	38	theme	glycogen	895:902	arg1	Non-diabetes					924:935	Non-diabetes	924:935	Non-diabetes	924:935	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	1	39	theme	Liver	81:85	arg1	glycogen					87:94	Liver glycogen	81:94	Liver glycogen	81:94	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	1	39	theme	Liver	81:85	arg1	polymer					125:131	a highly branched glucose polymer	99:131	a highly branched glucose polymer	99:131	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	2	40	theme	diabetes	374:381	arg1	models					364:369	mouse models	358:369	mouse models of diabetes	358:381	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	6	41	theme	diabetes	1139:1146	arg1	prevention					1148:1157	diabetes prevention	1139:1157	diabetes prevention	1139:1157	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	2	42	from	particles	324:332	arg1	solvents					345:352	certain solvents	337:352	certain solvents	337:352	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	2	43	theme	homeostasis	483:493	arg1	characteristic					495:508	the poor blood-sugar homeostasis characteristic	462:508	the poor blood-sugar homeostasis characteristic of the disease	462:523	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	6	44	dep	holds	1042:1046	arg1	α					1057:1057	α	1057:1057	α	1057:1057	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	1	45	from	~20 nm	155:160	arg1	diameter					165:172	diameter	165:172	diameter	165:172	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	2	46	theme	blood-sugar	471:481	arg1	characteristic					495:508	the poor blood-sugar homeostasis characteristic	462:508	the poor blood-sugar homeostasis characteristic of the disease	462:523	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	5	47	theme	Proteomic	812:820	arg1	analysis					822:829	Proteomic analysis	812:829	Proteomic analysis	812:829	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	5	48	theme	expressed	885:893	arg1	proteins					904:911	differentially expressed glycogen proteins	870:911	differentially expressed glycogen proteins (Diabetes/ Non-diabetes)	870:936	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	5	48	theme	expressed	885:893	arg1	Non-diabetes					924:935	Non-diabetes	924:935	Non-diabetes	924:935	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
36075306	6	49	theme	binding	1019:1025	arg1	mechanism					1027:1035	the binding mechanism	1015:1035	the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management	1015:1172	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	3	50	theme	liver	587:591	arg1	glycogen					593:600	liver glycogen	587:600	liver glycogen obtained from humans with diabetes	587:635	Here we tested if this α-particle fragility also occurred in liver glycogen obtained from humans with diabetes.					
36075306	6	51	dep	α	1057:1057	arg1	relevant					1127:1134	relevant	1127:1134	relevant	1127:1134	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	0	52	with	humans	37:42	arg1	diabetes					56:63	type 2 diabetes	49:63	type 2 diabetes	49:63	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	2	53	theme	breaking	299:306	arg1	up					308:309	breaking up	299:309	breaking up into smaller particles in certain solvents	299:352	Hepatic α particles have been shown to be structurally fragile (breaking up into smaller particles in certain solvents) in mouse models of diabetes; if occurring in vivo, the resulting small glycogen particles could exacerbate the poor blood-sugar homeostasis characteristic of the disease.					
36075306	0	54	theme	type	49:52	arg1	diabetes					56:63	type 2 diabetes	49:63	type 2 diabetes	49:63	The fragility of liver glycogen from humans with type 2 diabetes: A pilot study.					
36075306	6	55	theme	diabetic	1105:1112	arg1	glycogen					1114:1121	diabetic glycogen	1105:1121	diabetic glycogen	1105:1121	Identifying these proteins may give clues to the binding mechanism that holds together α particles together, which, being different in diabetic glycogen, is relevant to diabetes prevention and management.					
36075306	1	56	theme	branched	108:115	arg1	glycogen					87:94	Liver glycogen	81:94	Liver glycogen	81:94	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	1	56	theme	branched	108:115	arg1	polymer					125:131	a highly branched glucose polymer	99:131	a highly branched glucose polymer	99:131	Liver glycogen is a highly branched glucose polymer found as β particles (~20 nm in diameter), which can bind together into larger composite α particles.					
36075306	5	57	from	proteins	904:911	arg1	proteins					856:863	three candidate proteins	840:863	three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes)	840:936	Proteomic analysis revealed three candidate proteins from differentially expressed glycogen proteins (Diabetes/ Non-diabetes) in both human and mouse groups.					
35728636	9	0	theme	rat	1870:1872	arg1	model					1901:1905	a rat full-thickness skin wounds model	1868:1905	a rat full-thickness skin wounds model	1868:1905	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	8	1	theme	TTO	1613:1615	arg1	release					1595:1601	the release	1591:1601	the release of SA and TTO as a natural product	1591:1636	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	3	2	theme	different	566:574	arg1	layer					705:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer	657:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	2	theme	different	566:574	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	2	theme	different	566:574	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	9	3	theme	skin	1889:1892	arg1	model					1901:1905	a rat full-thickness skin wounds model	1868:1905	a rat full-thickness skin wounds model	1868:1905	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	10	4	theme	asymmetric	1931:1940	arg1	film					1942:1945	this versatile asymmetric film	1916:1945	this versatile asymmetric film	1916:1945	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	6	5	theme	antibacterial	1287:1299	arg1	properties					1301:1310	good antibacterial properties	1282:1310	good antibacterial properties	1282:1310	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	2	6	theme	chitosan-based	282:295	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	6	7	theme	bactericidal	1183:1194	arg1	concentration					1196:1208	the minimum inhibition and bactericidal concentration	1156:1208	concentration	1196:1208	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	9	8	theme	model	1901:1905	arg1	healing					1857:1863	the healing	1853:1863	the healing of a rat full-thickness skin wounds model	1853:1905	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	3	9	theme	hydrophilic	595:605	arg1	chitosan					607:614	hydrophilic chitosan	595:614	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	9	theme	hydrophilic	595:605	arg1	CS					617:618	CS	617:618	CS	617:618	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	2	10	theme	repair	326:331	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	1	11	theme	wound	208:212	arg1	microenvironment					188:203	the moist microenvironment	178:203	the moist microenvironment of wound	178:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	2	12	theme	asymmetric	309:318	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	3	13	theme	repair	639:644	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	13	theme	repair	639:644	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	1	14	theme	clinical	225:232	arg1	challenge					234:242	a clinical challenge	223:242	a clinical challenge in skin tissue healing	223:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	1	14	theme	clinical	225:232	arg1	damage					140:145	Oxidative stress damage	123:145	Oxidative stress damage caused by free radicals around the moist microenvironment of wound	123:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	9	15	theme	excellent	1705:1713	arg1	biocompatibility					1715:1730	excellent biocompatibility	1705:1730	excellent biocompatibility	1705:1730	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	10	16	contain	possesses	1947:1955	arg1	film					1942:1945	this versatile asymmetric film	1916:1945	this versatile asymmetric film	1916:1945	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	10	16	contain	possesses	1947:1955	arg2	potential					1963:1971	great potential	1957:1971	great potential for clinical management of wound healing and related soft tissue regeneration	1957:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	10	17	theme	clinical	1977:1984	arg1	management					1986:1995	clinical management	1977:1995	clinical management of wound healing and related soft tissue regeneration	1977:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	3	18	theme	SF	635:636	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	18	theme	SF	635:636	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	4	19	theme	skin	922:925	arg1	repair					927:932	skin repair	922:932	skin repair	922:932	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	8	20	theme	DPPH	1494:1497	arg1	rates					1499:1503	the DPPH rates	1490:1503	the DPPH rates of BAWRC film	1490:1517	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	8	20	theme	DPPH	1494:1497	arg1	%					1535:1535	up to 64.7 %	1524:1535	up to 64.7 %	1524:1535	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	10	21	theme	related	2018:2024	arg1	regeneration					2038:2049	related soft tissue regeneration	2018:2049	related soft tissue regeneration	2018:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	5	22	theme	infection	1057:1065	arg1	risk					1049:1052	the risk	1045:1052	the risk of infection	1045:1065	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	3	23	theme	chitosan	607:614	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	23	theme	chitosan	607:614	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	5	24	theme	distinctive	939:949	arg1	structure					962:970	The distinctive asymmetric structure	935:970	The distinctive asymmetric structure of BAWRC film	935:984	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	9	25	theme	good	1737:1740	arg1	capacity					1756:1763	good antibacterial capacity	1737:1763	good antibacterial capacity	1737:1763	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	6	26	theme	BAWRC	1217:1221	arg1	film					1223:1226	the BAWRC film	1213:1226	the BAWRC film	1213:1226	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	10	27	theme	healing	2006:2012	arg1	management					1986:1995	clinical management	1977:1995	clinical management of wound healing and related soft tissue regeneration	1977:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	0	28	theme	film	83:86	arg1	Construction					0:11	Construction	0:11	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.	0:121	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	7	29	from	effect	1451:1456	arg1	bacteriostasis					1461:1474	bacteriostasis	1461:1474	bacteriostasis	1461:1474	The content of biofilm formation was significantly reduced when the concentration of TTO exceeds 5 mg/mL, indicating TTO shows a positive effect on bacteriostasis.					
35728636	8	30	theme	film	1514:1517	arg1	rates					1499:1503	the DPPH rates	1490:1503	the DPPH rates of BAWRC film	1490:1517	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	8	30	theme	film	1514:1517	arg1	%					1535:1535	up to 64.7 %	1524:1535	up to 64.7 %	1524:1535	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	7	31	theme	TTO	1398:1400	arg1	concentration					1381:1393	the concentration	1377:1393	the concentration of TTO	1377:1400	The content of biofilm formation was significantly reduced when the concentration of TTO exceeds 5 mg/mL, indicating TTO shows a positive effect on bacteriostasis.					
35728636	4	32	theme	-entrapped	770:779	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	3	33	dep	layers	587:592	arg1	layer					705:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer	657:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	33	dep	layers	587:592	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	33	dep	layers	587:592	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	10	34	theme	tissue	2031:2036	arg1	regeneration					2038:2049	related soft tissue regeneration	2018:2049	related soft tissue regeneration	2018:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	0	35	theme	wound	108:112	arg1	healing					114:120	wound healing	108:120	wound healing	108:120	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	2	36	theme	self-assembly	446:458	arg1	technology					460:469	layer-by-layer self-assembly technology	431:469	layer-by-layer self-assembly technology for accelerated wound healing	431:499	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	5	37	theme	skin	1118:1121	arg1	healing					1129:1135	deep skin wound healing	1113:1135	deep skin wound healing	1113:1135	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	4	38	theme	ascorbate	756:764	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	2	39	theme	tissue	395:400	arg1	strategy					414:421	facilitated endogenous tissue engineering strategy	372:421	facilitated endogenous tissue engineering strategy	372:421	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	2	40	theme	accelerated	475:485	arg1	healing					493:499	accelerated wound healing	475:499	accelerated wound healing	475:499	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	9	41	theme	NIH3T3	1810:1815	arg1	cell					1817:1820	the NIH3T3 cell	1806:1820	the NIH3T3 cell	1806:1820	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	3	42	theme	asymmetric	506:515	arg1	characteristics					517:531	The asymmetric characteristics	502:531	The asymmetric characteristics	502:531	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	0	43	theme	chitosan-based	16:29	arg1	antioxidant					42:52	chitosan-based asymmetric antioxidant	16:52	chitosan-based asymmetric antioxidant	16:52	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	5	44	theme	BAWRC	975:979	arg1	film					981:984	BAWRC film	975:984	BAWRC film	975:984	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	7	45	theme	formation	1336:1344	arg1	content					1317:1323	The content	1313:1323	The content of biofilm formation	1313:1344	The content of biofilm formation was significantly reduced when the concentration of TTO exceeds 5 mg/mL, indicating TTO shows a positive effect on bacteriostasis.					
35728636	3	46	theme	tree	690:693	arg1	TTO					700:702	TTO	700:702	TTO	700:702	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	46	theme	tree	690:693	arg1	oil					695:697	a hydrophobic bacteriostatic tea tree oil	657:697	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	2	47	theme	layer-by-layer	431:444	arg1	technology					460:469	layer-by-layer self-assembly technology	431:469	layer-by-layer self-assembly technology for accelerated wound healing	431:499	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	0	48	theme	antioxidant	42:52	arg1	Construction					0:11	Construction	0:11	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.	0:121	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	3	49	theme	bacteriostatic	671:684	arg1	TTO					700:702	TTO	700:702	TTO	700:702	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	49	theme	bacteriostatic	671:684	arg1	oil					695:697	a hydrophobic bacteriostatic tea tree oil	657:697	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	0	50	theme	anti-inflammatory	58:74	arg1	film					83:86	anti-inflammatory repair film	58:86	anti-inflammatory repair film	58:86	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	4	51	theme	acid	806:809	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	2	52	theme	BAWRC	344:348	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	8	53	theme	natural	1622:1628	arg1	product					1630:1636	a natural product	1620:1636	a natural product	1620:1636	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	3	54	theme	functional	576:585	arg1	layer					705:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer	657:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	54	theme	functional	576:585	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	54	theme	functional	576:585	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	1	55	theme	skin	247:250	arg1	healing					259:265	skin tissue healing	247:265	skin tissue healing	247:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	8	56	from	%	1535:1535	arg1	addition					1480:1487	addition	1480:1487	addition	1480:1487	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	3	57	theme	rough	718:722	arg1	surface					724:730	a rough surface	716:730	a rough surface	716:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	8	58	theme	free	1655:1658	arg1	scavenging					1668:1677	free radical scavenging	1655:1677	free radical scavenging	1655:1677	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	4	59	theme	hydrophilic	869:879	arg1	layer					881:885	the hydrophilic layer	865:885	the hydrophilic layer	865:885	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	9	60	theme	full-thickness	1874:1887	arg1	model					1901:1905	a rat full-thickness skin wounds model	1868:1905	a rat full-thickness skin wounds model	1868:1905	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	2	61	theme	bioinspired	297:307	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	3	62	theme	/silk	620:624	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	62	theme	/silk	620:624	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	9	63	theme	wounds	1894:1899	arg1	model					1901:1905	a rat full-thickness skin wounds model	1868:1905	a rat full-thickness skin wounds model	1868:1905	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	10	64	theme	versatile	1921:1929	arg1	film					1942:1945	this versatile asymmetric film	1916:1945	this versatile asymmetric film	1916:1945	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	6	65	theme	good	1282:1285	arg1	properties					1301:1310	good antibacterial properties	1282:1310	good antibacterial properties	1282:1310	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	2	66	theme	novel	276:280	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	1	67	theme	moist	182:186	arg1	microenvironment					188:203	the moist microenvironment	178:203	the moist microenvironment of wound	178:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	2	68	theme	composite	333:341	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	7	69	theme	positive	1442:1449	arg1	effect					1451:1456	a positive effect	1440:1456	a positive effect on bacteriostasis	1440:1474	The content of biofilm formation was significantly reduced when the concentration of TTO exceeds 5 mg/mL, indicating TTO shows a positive effect on bacteriostasis.					
35728636	10	70	theme	great	1957:1961	arg1	potential					1963:1971	great potential	1957:1971	great potential for clinical management of wound healing and related soft tissue regeneration	1957:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	2	71	theme	wound	320:324	arg1	film					351:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film	274:354	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	6	72	theme	minimum	1160:1166	arg1	inhibition					1168:1177	the minimum inhibition and bactericidal concentration	1156:1208	inhibition	1168:1177	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	6	72	theme	minimum	1160:1166	arg1	1.25					1233:1236	1.25	1233:1236	1.25	1233:1236	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	9	73	theme	BAWRC	1684:1688	arg1	film					1690:1693	The BAWRC film	1680:1693	The BAWRC film	1680:1693	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	5	74	theme	external	1076:1083	arg1	environment					1085:1095	the external environment	1072:1095	the external environment	1072:1095	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	1	75	theme	stress	133:138	arg1	challenge					234:242	a clinical challenge	223:242	a clinical challenge in skin tissue healing	223:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	1	75	theme	stress	133:138	arg1	damage					140:145	Oxidative stress damage	123:145	Oxidative stress damage caused by free radicals around the moist microenvironment of wound	123:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	4	76	theme	antioxidant	897:907	arg1	response					909:916	antioxidant response	897:916	antioxidant response	897:916	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	1	77	from	challenge	234:242	arg1	healing					259:265	skin tissue healing	247:265	skin tissue healing	247:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	5	78	theme	synergistic	1001:1011	arg1	effects					1013:1019	synergistic effects	1001:1019	synergistic effects	1001:1019	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	8	79	theme	BAWRC	1508:1512	arg1	film					1514:1517	BAWRC film	1508:1517	BAWRC film	1508:1517	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	6	80	theme	film	1223:1226	arg1	inhibition					1168:1177	the minimum inhibition and bactericidal concentration	1156:1208	inhibition	1168:1177	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	6	80	theme	film	1223:1226	arg1	concentration					1196:1208	the minimum inhibition and bactericidal concentration	1156:1208	concentration	1196:1208	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	6	80	theme	film	1223:1226	arg1	1.25					1233:1236	1.25	1233:1236	1.25	1233:1236	Results show that the minimum inhibition and bactericidal concentration of the BAWRC film were 1.25 and 6.25 mg/mL, respectively, demonstrating good antibacterial properties.					
35728636	3	81	with	layer	646:650	arg1	surface					724:730	a rough surface	716:730	a rough surface	716:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	1	82	theme	free	157:160	arg1	radicals					162:169	free radicals	157:169	free radicals around the moist microenvironment of wound	157:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	9	83	theme	antibacterial	1742:1754	arg1	capacity					1756:1763	good antibacterial capacity	1737:1763	good antibacterial capacity	1737:1763	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	3	84	theme	fibroin	626:632	arg1	layer					646:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	hydrophilic chitosan (CS)/silk fibroin (SF) repair layer	595:650	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	84	theme	fibroin	626:632	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	10	85	theme	wound	2000:2004	arg1	healing					2006:2012	wound healing	2000:2012	wound healing	2000:2012	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	10	86	theme	regeneration	2038:2049	arg1	management					1986:1995	clinical management	1977:1995	clinical management of wound healing and related soft tissue regeneration	1977:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	0	87	theme	healing	114:120	arg1	acceleration					92:103	acceleration	92:103	acceleration of wound healing	92:120	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	5	88	theme	film	981:984	arg1	structure					962:970	The distinctive asymmetric structure	935:970	The distinctive asymmetric structure of BAWRC film	935:984	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	10	89	theme	soft	2026:2029	arg1	regeneration					2038:2049	related soft tissue regeneration	2018:2049	related soft tissue regeneration	2018:2049	Herein, this versatile asymmetric film possesses great potential for clinical management of wound healing and related soft tissue regeneration.					
35728636	5	90	theme	deep	1113:1116	arg1	healing					1129:1135	deep skin wound healing	1113:1135	deep skin wound healing	1113:1135	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	4	91	theme	poly	781:784	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	2	92	theme	engineering	402:412	arg1	strategy					414:421	facilitated endogenous tissue engineering strategy	372:421	facilitated endogenous tissue engineering strategy	372:421	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	5	93	theme	wound	1123:1127	arg1	healing					1129:1135	deep skin wound healing	1113:1135	deep skin wound healing	1113:1135	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	5	94	theme	asymmetric	951:960	arg1	structure					962:970	The distinctive asymmetric structure	935:970	The distinctive asymmetric structure of BAWRC film	935:984	The distinctive asymmetric structure of BAWRC film endows it with synergistic effects, i.e., protects against the risk of infection from the external environment and facilitates deep skin wound healing.					
35728636	2	95	theme	wound	487:491	arg1	healing					493:499	accelerated wound healing	475:499	accelerated wound healing	475:499	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	4	96	theme	sodium	749:754	arg1	SA					767:768	SA	767:768	SA	767:768	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	4	96	theme	sodium	749:754	arg1	ascorbate					756:764	sodium ascorbate	749:764	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	2	97	theme	endogenous	384:393	arg1	strategy					414:421	facilitated endogenous tissue engineering strategy	372:421	facilitated endogenous tissue engineering strategy	372:421	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	0	98	theme	asymmetric	31:40	arg1	antioxidant					42:52	chitosan-based asymmetric antioxidant	16:52	chitosan-based asymmetric antioxidant	16:52	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	7	99	theme	biofilm	1328:1334	arg1	formation					1336:1344	biofilm formation	1328:1344	biofilm formation	1328:1344	The content of biofilm formation was significantly reduced when the concentration of TTO exceeds 5 mg/mL, indicating TTO shows a positive effect on bacteriostasis.					
35728636	9	100	theme	cell	1817:1820	arg1	adhesion					1776:1783	adhesion	1776:1783	adhesion	1776:1783	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	9	100	theme	cell	1817:1820	arg1	proliferation					1789:1801	proliferation	1789:1801	proliferation	1789:1801	The BAWRC film exhibited excellent biocompatibility, and good antibacterial capacity, enhancing adhesion and proliferation of the NIH3T3 cell in vitro, further facilitating the healing of a rat full-thickness skin wounds model.					
35728636	3	101	theme	tea	686:688	arg1	TTO					700:702	TTO	700:702	TTO	700:702	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	101	theme	tea	686:688	arg1	oil					695:697	a hydrophobic bacteriostatic tea tree oil	657:697	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	2	102	theme	facilitated	372:382	arg1	strategy					414:421	facilitated endogenous tissue engineering strategy	372:421	facilitated endogenous tissue engineering strategy	372:421	Here, a novel chitosan-based bioinspired asymmetric wound repair composite (BAWRC) film was designed by facilitated endogenous tissue engineering strategy through layer-by-layer self-assembly technology for accelerated wound healing.					
35728636	3	103	theme	hydrophobic	659:669	arg1	TTO					700:702	TTO	700:702	TTO	700:702	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	103	theme	hydrophobic	659:669	arg1	oil					695:697	a hydrophobic bacteriostatic tea tree oil	657:697	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	4	104	theme	PLGA	813:816	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	0	105	theme	repair	76:81	arg1	film					83:86	anti-inflammatory repair film	58:86	anti-inflammatory repair film	58:86	Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing.					
35728636	1	106	theme	Oxidative	123:131	arg1	challenge					234:242	a clinical challenge	223:242	a clinical challenge in skin tissue healing	223:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	1	106	theme	Oxidative	123:131	arg1	damage					140:145	Oxidative stress damage	123:145	Oxidative stress damage caused by free radicals around the moist microenvironment of wound	123:212	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
35728636	3	107	theme	oil	695:697	arg1	layer					705:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer	657:709	a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	657:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	3	107	theme	oil	695:697	arg1	layers					587:592	two different functional layers	562:592	two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface	562:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	4	108	theme	lactic-co-glycolic	787:804	arg1	microspheres					819:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres	749:830	Simultaneously, sodium ascorbate (SA)-entrapped poly (lactic-co-glycolic acid) (PLGA) microspheres are distributed homogeneously in the hydrophilic layer to induce antioxidant response for skin repair.					
35728636	8	109	theme	radical	1660:1666	arg1	scavenging					1668:1677	free radical scavenging	1655:1677	free radical scavenging	1655:1677	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	8	110	theme	SA	1606:1607	arg1	release					1595:1601	the release	1591:1601	the release of SA and TTO as a natural product	1591:1636	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	8	111	dep	64.7 	1530:1534	arg1	to					1527:1528	to	1527:1528	to	1527:1528	In addition, the DPPH rates of BAWRC film were up to 64.7 % after incubation for 12 h, which was ascribed to that the release of SA and TTO as a natural product could accelerate free radical scavenging.					
35728636	3	112	with	layer	705:709	arg1	surface					724:730	a rough surface	716:730	a rough surface	716:730	The asymmetric characteristics were skillfully reflected by two different functional layers: hydrophilic chitosan (CS)/silk fibroin (SF) repair layer, and a hydrophobic bacteriostatic tea tree oil (TTO) layer with a rough surface.					
35728636	1	113	theme	tissue	252:257	arg1	healing					259:265	skin tissue healing	247:265	skin tissue healing	247:265	Oxidative stress damage caused by free radicals around the moist microenvironment of wound has been a clinical challenge in skin tissue healing.					
36181445	2	0	theme	soluble	583:589	arg1	DFs					591:593	5% w/v low-viscosity soluble DFs	562:593	5% w/v low-viscosity soluble DFs in drinking water for 2 weeks	562:623	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	7	1	theme	particular	1247:1256	arg1	α-cyclodextrin					1258:1271	particular α-cyclodextrin	1247:1271	particular α-cyclodextrin	1247:1271	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	0	2	theme	Intestinal	167:176	arg1	Inflammation					178:189	Intestinal Inflammation	167:189	Intestinal Inflammation	167:189	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	3	theme	low-viscosity	257:269	arg1	DFs					295:297	DFs	295:297	DFs	295:297	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	3	theme	low-viscosity	257:269	arg1	fibers					287:292	four low-viscosity soluble dietary fibers	252:292	four low-viscosity soluble dietary fibers (DFs)	252:298	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	9	4	theme	exploratory	1560:1570	arg1	study					1572:1576	This exploratory study	1555:1576	This exploratory study	1555:1576	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	2	5	theme	w/v	565:567	arg1	DFs					591:593	5% w/v low-viscosity soluble DFs	562:593	5% w/v low-viscosity soluble DFs in drinking water for 2 weeks	562:623	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	6	6	theme	pTregs	1204:1209	arg1	induction					1183:1191	marked induction	1176:1191	marked induction of colonic pTregs	1176:1209	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	1	7	theme	dietary	279:285	arg1	DFs					295:297	DFs	295:297	DFs	295:297	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	7	theme	dietary	279:285	arg1	fibers					287:292	four low-viscosity soluble dietary fibers	252:292	four low-viscosity soluble dietary fibers (DFs)	252:298	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	3	8	theme	rRNA	681:684	arg1	sequencing					686:695	16S rRNA sequencing	677:695	16S rRNA sequencing	677:695	The gut microbiota composition is determined using 16S rRNA sequencing.					
36181445	1	9	theme	regulatory	457:466	arg1	pTregs					477:482	pTregs	477:482	pTregs	477:482	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	9	theme	regulatory	457:466	arg1	cells					470:474	colonic peripherally induced regulatory T cells	428:474	colonic peripherally induced regulatory T cells (pTregs)	428:483	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	6	10	theme	marked	1176:1181	arg1	induction					1183:1191	marked induction	1176:1191	marked induction of colonic pTregs	1176:1209	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	1	11	theme	cells	470:474	arg1	production					402:411	short-chain fatty acid (SCFA) production	372:411	short-chain fatty acid (SCFA) production	372:411	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	11	theme	cells	470:474	arg1	colitis					503:509	experimental colitis	490:509	experimental colitis	490:509	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	11	theme	cells	470:474	arg1	proportion					414:423	proportion	414:423	proportion of colonic peripherally induced regulatory T cells (pTregs)	414:483	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	2	12	theme	RESULTS	532:538	arg1	Mice					540:543	METHODS AND RESULTS Mice	520:543	METHODS AND RESULTS Mice	520:543	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	0	13	theme	Preventive	119:128	arg1	Application					130:140	A Possible Preventive Application	108:140	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	14	theme	fatty	384:388	arg1	production					402:411	short-chain fatty acid (SCFA) production	372:411	short-chain fatty acid (SCFA) production	372:411	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	5	15	theme	low-viscosity	808:820	arg1	DFs					830:832	All low-viscosity soluble DFs	804:832	All low-viscosity soluble DFs	804:832	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	2	16	theme	METHODS	520:526	arg1	Mice					540:543	METHODS AND RESULTS Mice	520:543	METHODS AND RESULTS Mice	520:543	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	8	17	theme	abundance	1481:1489	arg1	terms					1462:1466	terms	1462:1466	terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development	1462:1552	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	2	18	theme	5	562:562	arg1	%					563:563	%	563:563	%	563:563	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	8	19	theme	SCFA	1492:1495	arg1	concentration					1497:1509	SCFA concentration	1492:1509	SCFA concentration	1492:1509	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	7	20	from	fibers	1236:1241	arg1	α-cyclodextrin					1258:1271	particular α-cyclodextrin	1247:1271	particular α-cyclodextrin	1247:1271	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	4	21	theme	Luminal	698:704	arg1	SCFAs					706:710	Luminal SCFAs	698:710	Luminal SCFAs	698:710	Luminal SCFAs are quantified by gas chromatography, and colonic pTregs are analyzed using flow cytometry.					
36181445	6	22	theme	low-viscosity	1023:1035	arg1	DFs					1045:1047	two low-viscosity soluble DFs	1019:1047	two low-viscosity soluble DFs	1019:1047	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	8	23	theme	population	1518:1527	arg1	terms					1462:1466	terms	1462:1466	terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development	1462:1552	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	8	24	theme	CONCLUSION	1345:1354	arg1	Mice					1356:1359	CONCLUSION Mice	1345:1359	CONCLUSION Mice administered any low-viscosity soluble DF	1345:1401	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	1	25	from	proportion	414:423	arg1	mice					514:517	mice	514:517	mice	514:517	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	5	26	theme	bacteria	867:874	arg1	growth					846:851	the growth	842:851	the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens	842:935	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	1	27	from	production	402:411	arg1	mice					514:517	mice	514:517	mice	514:517	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	8	28	theme	development	1542:1552	arg1	terms					1462:1466	terms	1462:1466	terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development	1462:1552	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	8	29	theme	low-viscosity	1378:1390	arg1	DF					1400:1401	any low-viscosity soluble DF	1374:1401	any low-viscosity soluble DF	1374:1401	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	1	30	theme	microbiota	348:357	arg1	composition					359:369	microbiota composition	348:369	microbiota composition	348:369	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	9	31	theme	α-cyclodextrin	1610:1623	arg1	strategy					1643:1650	a possible strategy	1632:1650	a possible strategy for the prevention of colitis	1632:1680	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	9	31	theme	α-cyclodextrin	1610:1623	arg1	administration					1592:1605	administration	1592:1605	administration of α-cyclodextrin	1592:1623	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	6	32	theme	commensal	1089:1097	arg1	bacteria					1099:1106	commensal bacteria	1089:1106	commensal bacteria	1089:1106	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	8	33	theme	comparable	1408:1417	arg1	compositions					1434:1445	comparable gut microbiota compositions	1408:1445	comparable gut microbiota compositions	1408:1445	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	1	34	theme	fibers	287:292	arg1	impact					242:247	the impact	238:247	the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment	238:333	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	35	from	colitis	503:509	arg1	mice					514:517	mice	514:517	mice	514:517	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	8	36	theme	microbiota	1423:1432	arg1	compositions					1434:1445	comparable gut microbiota compositions	1408:1445	comparable gut microbiota compositions	1408:1445	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	9	37	theme	possible	1634:1641	arg1	strategy					1643:1650	a possible strategy	1632:1650	a possible strategy for the prevention of colitis	1632:1680	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	9	37	theme	possible	1634:1641	arg1	administration					1592:1605	administration	1592:1605	administration of α-cyclodextrin	1592:1623	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	4	38	theme	flow	788:791	arg1	cytometry					793:801	flow cytometry	788:801	flow cytometry	788:801	Luminal SCFAs are quantified by gas chromatography, and colonic pTregs are analyzed using flow cytometry.					
36181445	0	39	theme	Soluble	28:34	arg1	Fibers					44:49	Low-Viscosity Soluble Dietary Fibers	14:49	Low-Viscosity Soluble Dietary Fibers	14:49	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	7	40	theme	colitis	1324:1330	arg1	model					1338:1342	a colitis mouse model	1322:1342	a colitis mouse model	1322:1342	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	0	41	theme	Intestinal	54:63	arg1	Microenvironment					65:80	Intestinal Microenvironment	54:80	Intestinal Microenvironment	54:80	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	42	dep	SCOPE	192:196	arg1	is					224:225	is	224:225	is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice	224:517	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	0	43	theme	Fibers	44:49	arg1	Impact					4:9	The Impact	0:9	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	44	theme	intestinal	307:316	arg1	microenvironment					318:333	the intestinal microenvironment	303:333	the intestinal microenvironment	303:333	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	9	45	theme	colitis	1674:1680	arg1	prevention					1660:1669	the prevention	1656:1669	the prevention of colitis	1656:1680	This exploratory study suggests that administration of α-cyclodextrin may be a possible strategy for the prevention of colitis.					
36181445	7	46	theme	anti-inflammatory	1290:1306	arg1	properties					1308:1317	remarkable anti-inflammatory properties	1279:1317	remarkable anti-inflammatory properties	1279:1317	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	3	47	theme	gut	630:632	arg1	composition					645:655	The gut microbiota composition	626:655	The gut microbiota composition	626:655	The gut microbiota composition is determined using 16S rRNA sequencing.					
36181445	8	48	theme	bacterial	1471:1479	arg1	abundance					1481:1489	bacterial abundance	1471:1489	bacterial abundance	1471:1489	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	3	49	theme	16S	677:679	arg1	sequencing					686:695	16S rRNA sequencing	677:695	16S rRNA sequencing	677:695	The gut microbiota composition is determined using 16S rRNA sequencing.					
36181445	2	50	theme	low-viscosity	569:581	arg1	DFs					591:593	5% w/v low-viscosity soluble DFs	562:593	5% w/v low-viscosity soluble DFs in drinking water for 2 weeks	562:623	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	0	51	from	Inflammation	178:189	arg1	Application					130:140	A Possible Preventive Application	108:140	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	52	theme	colonic	428:434	arg1	pTregs					477:482	pTregs	477:482	pTregs	477:482	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	52	theme	colonic	428:434	arg1	cells					470:474	colonic peripherally induced regulatory T cells	428:474	colonic peripherally induced regulatory T cells (pTregs)	428:483	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	53	theme	soluble	271:277	arg1	DFs					295:297	DFs	295:297	DFs	295:297	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	53	theme	soluble	271:277	arg1	fibers					287:292	four low-viscosity soluble dietary fibers	252:292	four low-viscosity soluble dietary fibers (DFs)	252:298	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	2	54	theme	%	563:563	arg1	DFs					591:593	5% w/v low-viscosity soluble DFs	562:593	5% w/v low-viscosity soluble DFs in drinking water for 2 weeks	562:623	METHODS AND RESULTS Mice are administered 5% w/v low-viscosity soluble DFs in drinking water for 2 weeks.					
36181445	6	55	theme	colonic	1196:1202	arg1	pTregs					1204:1209	colonic pTregs	1196:1209	colonic pTregs	1196:1209	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	1	56	theme	induced	449:455	arg1	pTregs					477:482	pTregs	477:482	pTregs	477:482	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	56	theme	induced	449:455	arg1	cells					470:474	colonic peripherally induced regulatory T cells	428:474	colonic peripherally induced regulatory T cells (pTregs)	428:483	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	57	theme	T	468:468	arg1	pTregs					477:482	pTregs	477:482	pTregs	477:482	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	57	theme	T	468:468	arg1	cells					470:474	colonic peripherally induced regulatory T cells	428:474	colonic peripherally induced regulatory T cells (pTregs)	428:483	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	0	58	theme	Alpha-Cyclodextrin	145:162	arg1	Application					130:140	A Possible Preventive Application	108:140	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	59	theme	acid	390:393	arg1	production					402:411	short-chain fatty acid (SCFA) production	372:411	short-chain fatty acid (SCFA) production	372:411	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	5	60	theme	soluble	822:828	arg1	DFs					830:832	All low-viscosity soluble DFs	804:832	All low-viscosity soluble DFs	804:832	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	8	61	theme	concentration	1497:1509	arg1	terms					1462:1466	terms	1462:1466	terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development	1462:1552	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	1	62	from	impact	242:247	arg1	microenvironment					318:333	the intestinal microenvironment	303:333	the intestinal microenvironment	303:333	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	63	theme	SCFA	396:399	arg1	production					402:411	short-chain fatty acid (SCFA) production	372:411	short-chain fatty acid (SCFA) production	372:411	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	8	64	theme	pTreg	1512:1516	arg1	population					1518:1527	pTreg population	1512:1527	pTreg population	1512:1527	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	6	65	theme	soluble	1037:1043	arg1	DFs					1045:1047	two low-viscosity soluble DFs	1019:1047	two low-viscosity soluble DFs	1019:1047	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	6	66	theme	propionate	1140:1149	arg1	accumulation					1124:1135	the accumulation	1120:1135	the accumulation of propionate and butyrate	1120:1162	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	5	67	theme	beneficial	856:865	arg1	muciniphila					896:906	muciniphila	896:906	muciniphila	896:906	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	5	67	theme	beneficial	856:865	arg1	acidifaciens					924:935	acidifaciens	924:935	acidifaciens	924:935	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	5	67	theme	beneficial	856:865	arg1	bacteria					867:874	beneficial bacteria	856:874	beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens	856:935	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	8	68	theme	colitis	1534:1540	arg1	development					1542:1552	colitis development	1534:1552	colitis development	1534:1552	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	0	69	theme	Experimental	86:97	arg1	Colitis					99:105	Experimental Colitis	86:105	Experimental Colitis	86:105	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	0	70	from	Impact	4:9	arg1	Microenvironment					65:80	Intestinal Microenvironment	54:80	Intestinal Microenvironment	54:80	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	0	70	from	Impact	4:9	arg1	Colitis					99:105	Experimental Colitis	86:105	Experimental Colitis	86:105	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	5	71	theme	pathogenic	956:965	arg1	bacteria					967:974	pathogenic bacteria	956:974	pathogenic bacteria such as Clostridium perfringens	956:1006	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	5	71	theme	pathogenic	956:965	arg1	perfringens					996:1006	Clostridium perfringens	984:1006	Clostridium perfringens	984:1006	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	4	72	theme	gas	730:732	arg1	chromatography					734:747	gas chromatography	730:747	gas chromatography	730:747	Luminal SCFAs are quantified by gas chromatography, and colonic pTregs are analyzed using flow cytometry.					
36181445	0	73	theme	Possible	110:117	arg1	Application					130:140	A Possible Preventive Application	108:140	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	1	74	theme	composition	359:369	arg1	terms					339:343	terms	339:343	terms of microbiota composition	339:369	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	1	75	theme	study	218:222	arg1	purpose					202:208	The purpose	198:208	The purpose of this study	198:222	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	6	76	theme	bacteria	1099:1106	arg1	abundance					1076:1084	the abundance	1072:1084	the abundance of commensal bacteria	1072:1106	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	8	77	theme	soluble	1392:1398	arg1	DF					1400:1401	any low-viscosity soluble DF	1374:1401	any low-viscosity soluble DF	1374:1401	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	1	78	theme	short-chain	372:382	arg1	production					402:411	short-chain fatty acid (SCFA) production	372:411	short-chain fatty acid (SCFA) production	372:411	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	0	79	theme	Low-Viscosity	14:26	arg1	Fibers					44:49	Low-Viscosity Soluble Dietary Fibers	14:49	Low-Viscosity Soluble Dietary Fibers	14:49	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	7	80	theme	mouse	1332:1336	arg1	model					1338:1342	a colitis mouse model	1322:1342	a colitis mouse model	1322:1342	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	8	81	theme	gut	1419:1421	arg1	compositions					1434:1445	comparable gut microbiota compositions	1408:1445	comparable gut microbiota compositions	1408:1445	CONCLUSION Mice administered any low-viscosity soluble DF show comparable gut microbiota compositions, but differ in terms of bacterial abundance, SCFA concentration, pTreg population, and colitis development.					
36181445	0	82	theme	Dietary	36:42	arg1	Fibers					44:49	Low-Viscosity Soluble Dietary Fibers	14:49	Low-Viscosity Soluble Dietary Fibers	14:49	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	6	83	theme	butyrate	1155:1162	arg1	accumulation					1124:1135	the accumulation	1120:1135	the accumulation of propionate and butyrate	1120:1162	Moreover, two low-viscosity soluble DFs significantly increase the abundance of commensal bacteria and promote the accumulation of propionate and butyrate, leading to marked induction of colonic pTregs.					
36181445	3	84	theme	microbiota	634:643	arg1	composition					645:655	The gut microbiota composition	626:655	The gut microbiota composition	626:655	The gut microbiota composition is determined using 16S rRNA sequencing.					
36181445	5	85	theme	Clostridium	984:994	arg1	perfringens					996:1006	Clostridium perfringens	984:1006	Clostridium perfringens	984:1006	All low-viscosity soluble DFs promote the growth of beneficial bacteria such as Akkermansia muciniphila and Bacteroides acidifaciens, while eliminating pathogenic bacteria such as Clostridium perfringens.					
36181445	7	86	theme	remarkable	1279:1288	arg1	properties					1308:1317	remarkable anti-inflammatory properties	1279:1317	remarkable anti-inflammatory properties	1279:1317	Consistently, these two fibers, in particular α-cyclodextrin, show remarkable anti-inflammatory properties in a colitis mouse model.					
36181445	0	87	from	Alpha-Cyclodextrin	145:162	arg1	Inflammation					178:189	Intestinal Inflammation	167:189	Intestinal Inflammation	167:189	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	4	88	theme	colonic	754:760	arg1	pTregs					762:767	colonic pTregs	754:767	colonic pTregs	754:767	Luminal SCFAs are quantified by gas chromatography, and colonic pTregs are analyzed using flow cytometry.					
36181445	1	89	theme	experimental	490:501	arg1	colitis					503:509	experimental colitis	490:509	experimental colitis	490:509	SCOPE The purpose of this study is to compare the impact of four low-viscosity soluble dietary fibers (DFs) on the intestinal microenvironment, in terms of microbiota composition, short-chain fatty acid (SCFA) production, proportion of colonic peripherally induced regulatory T cells (pTregs), and experimental colitis in mice.					
36181445	0	90	dep	Impact	4:9	arg1	Application					130:140	A Possible Preventive Application	108:140	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.	0:190	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
36181445	0	91	from	Application	130:140	arg1	Inflammation					178:189	Intestinal Inflammation	167:189	Intestinal Inflammation	167:189	The Impact of Low-Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha-Cyclodextrin in Intestinal Inflammation.					
35183725	6	0	theme	proposed	914:921	arg1	strategy					923:930	The proposed strategy	910:930	The proposed strategy	910:930	The proposed strategy was applied to upgrade orange peel waste and sugarcane bagasse to demonstrate how it can be applied.					
35183725	3	1	theme	existing	501:508	arg1	routes					510:515	existing routes	501:515	existing routes	501:515	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	5	2	theme	decision	779:786	arg1	tools					788:792	decision tools	779:792	decision tools to designers	779:805	This strategy aims to give decision tools to designers to filter and reduce the number of options to be considered when proposing an alternative biomass use.					
35183725	7	3	theme	biorefineries	1129:1141	arg1	design					1143:1148	the biorefineries design	1125:1148	the biorefineries design	1125:1148	In conclusion, selecting of bioprocesses and considering the proposed strategycould improve the biorefineries design.					
35183725	3	4	theme	routes	510:515	arg1	compendium					487:496	compendium	487:496	compendium of existing routes	487:515	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	1	5	theme	process	245:251	arg1	designers					253:261	process designers	245:261	process designers	245:261	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	0	6	theme	design	96:101	arg1	step					103:106	the conceptual design step	81:106	the conceptual design step	81:106	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	0	7	from	Analysis	0:7	arg1	step					103:106	the conceptual design step	81:106	the conceptual design step	81:106	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	4	8	theme	bioprocesses	604:615	arg1	selection					617:625	a supported bioprocesses selection	592:625	a supported bioprocesses selection	592:625	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	0	9	theme	conceptual	85:94	arg1	step					103:106	the conceptual design step	81:106	the conceptual design step	81:106	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	5	10	theme	biomass	897:903	arg1	use					905:907	an alternative biomass use	882:907	an alternative biomass use	882:907	This strategy aims to give decision tools to designers to filter and reduce the number of options to be considered when proposing an alternative biomass use.					
35183725	4	11	theme	supported	594:602	arg1	selection					617:625	a supported bioprocesses selection	592:625	a supported bioprocesses selection	592:625	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	2	12	theme	designed	275:282	arg1	processes					284:292	Conceptual designed processes	264:292	Conceptual designed processes	264:292	Conceptual designed processes do not overcome this stage because aspects such as context and technological readiness level are left aside.					
35183725	6	13	theme	sugarcane	977:985	arg1	bagasse					987:993	sugarcane bagasse	977:993	sugarcane bagasse	977:993	The proposed strategy was applied to upgrade orange peel waste and sugarcane bagasse to demonstrate how it can be applied.					
35183725	7	14	theme	proposed	1094:1101	arg1	strategycould					1103:1115	the proposed strategycould	1090:1115	the proposed strategycould	1090:1115	In conclusion, selecting of bioprocesses and considering the proposed strategycould improve the biorefineries design.					
35183725	2	15	theme	Conceptual	264:273	arg1	processes					284:292	Conceptual designed processes	264:292	Conceptual designed processes	264:292	Conceptual designed processes do not overcome this stage because aspects such as context and technological readiness level are left aside.					
35183725	1	16	theme	Process	169:175	arg1	sustainability					177:190	Process sustainability	169:190	Process sustainability	169:190	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	4	17	theme	material	686:693	arg1	context					703:709	the context	699:709	the context where biomass is produced and processed	699:749	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	4	17	theme	material	686:693	arg1	composition					663:673	the chemical composition	650:673	the chemical composition of the raw material	650:693	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	4	18	theme	raw	682:684	arg1	material					686:693	the raw material	678:693	the raw material	678:693	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	0	19	theme	routes	16:21	arg1	Analysis					0:7	Analysis	0:7	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.	0:167	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	6	20	theme	peel	962:965	arg1	waste					967:971	upgrade orange peel waste	947:971	upgrade orange peel waste	947:971	The proposed strategy was applied to upgrade orange peel waste and sugarcane bagasse to demonstrate how it can be applied.					
35183725	3	21	theme	sustainable	526:536	arg1	development					538:548	sustainable development	526:548	sustainable development	526:548	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	0	22	theme	biomass	27:33	arg1	processing					35:44	biomass processing	27:44	biomass processing towards sustainable development	27:76	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	6	23	theme	orange	955:960	arg1	waste					967:971	upgrade orange peel waste	947:971	upgrade orange peel waste	947:971	The proposed strategy was applied to upgrade orange peel waste and sugarcane bagasse to demonstrate how it can be applied.					
35183725	5	24	theme	options	842:848	arg1	number					832:837	the number	828:837	the number of options to be considered when proposing an alternative biomass use	828:907	This strategy aims to give decision tools to designers to filter and reduce the number of options to be considered when proposing an alternative biomass use.					
35183725	3	25	theme	different	446:454	arg1	routes					467:472	different processing routes	446:472	different processing routes	446:472	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	6	26	theme	upgrade	947:953	arg1	waste					967:971	upgrade orange peel waste	947:971	upgrade orange peel waste	947:971	The proposed strategy was applied to upgrade orange peel waste and sugarcane bagasse to demonstrate how it can be applied.					
35183725	3	27	theme	processing	456:465	arg1	routes					467:472	different processing routes	446:472	different processing routes	446:472	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	8	28	theme	more	1160:1163	arg1	bioprocesses					1165:1176	more bioprocesses	1160:1176	more bioprocesses	1160:1176	Even so, more bioprocesses must be included.					
35183725	3	29	dep	consider	437:444	arg1	compendium					487:496	compendium	487:496	compendium of existing routes	487:515	This paper proposes a strategy to consider different processing routes for biomass (compendium of existing routes) towards sustainable development.					
35183725	0	30	theme	portfolio	158:166	arg1	compendium					131:140	the compendium	127:140	the compendium of bioprocesses portfolio	127:166	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	1	31	theme	most	212:215	arg1	issues					229:234	the most challenging issues	208:234	the most challenging issues faced by process designers	208:261	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	0	32	theme	bioprocesses	145:156	arg1	portfolio					158:166	bioprocesses portfolio	145:166	bioprocesses portfolio	145:166	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	5	33	theme	alternative	885:895	arg1	use					905:907	an alternative biomass use	882:907	an alternative biomass use	882:907	This strategy aims to give decision tools to designers to filter and reduce the number of options to be considered when proposing an alternative biomass use.					
35183725	1	34	theme	challenging	217:227	arg1	issues					229:234	the most challenging issues	208:234	the most challenging issues faced by process designers	208:261	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	4	35	theme	chemical	654:661	arg1	composition					663:673	the chemical composition	650:673	the chemical composition of the raw material	650:693	The strategy comprises five stages where a supported bioprocesses selection is made by considering the chemical composition of the raw material and the context where biomass is produced and processed.					
35183725	2	36	theme	readiness	371:379	arg1	level					381:385	technological readiness level	357:385	technological readiness level	357:385	Conceptual designed processes do not overcome this stage because aspects such as context and technological readiness level are left aside.					
35183725	1	37	theme	issues	229:234	arg1	issues					229:234	the most challenging issues	208:234	the most challenging issues faced by process designers	208:261	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	1	37	theme	issues	229:234	arg1	one					201:203	one	201:203	one	201:203	Process sustainability has been one of the most challenging issues faced by process designers.					
35183725	0	38	theme	sustainable	54:64	arg1	development					66:76	sustainable development	54:76	sustainable development	54:76	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	0	39	dep	Analysis	0:7	arg1	Strategy					109:116	Strategy	109:116	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.	0:167	Analysis of the routes for biomass processing towards sustainable development in the conceptual design step: Strategy based on the compendium of bioprocesses portfolio.					
35183725	2	40	theme	technological	357:369	arg1	level					381:385	technological readiness level	357:385	technological readiness level	357:385	Conceptual designed processes do not overcome this stage because aspects such as context and technological readiness level are left aside.					
37270119	5	0	theme	low	775:777	arg1	reflectance					779:789	its extremely low reflectance	761:789	its extremely low reflectance of electromagnetic waves	761:814	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	5	1	theme	electromagnetic	879:893	arg1	layer					844:848	the outermost layer	830:848	the outermost layer of the material	830:864	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	5	1	theme	electromagnetic	879:893	arg1	waves					895:899	more electromagnetic waves	874:899	more electromagnetic waves	874:899	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	8	2	theme	excellent	1297:1305	arg1	surface					1307:1313	excellent surface	1297:1313	excellent surface	1297:1313	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	7	3	theme	SBTFX-Y	1089:1095	arg1	films					1097:1101	the SBTFX-Y films	1085:1101	the SBTFX-Y films	1085:1101	What's more, the SBTFX-Y films show excellent mechanical properties, hydrophobicity and flexibility.					
37270119	5	4	theme	electromagnetic	794:808	arg1	waves					810:814	electromagnetic waves	794:814	electromagnetic waves	794:814	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	4	5	theme	waves	691:695	arg1	waves					691:695	radio waves	685:695	radio waves	685:695	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	4	5	theme	waves	691:695	arg1	amount					675:680	a large amount	667:680	a large amount of radio waves	667:695	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	5	6	theme	more	874:877	arg1	layer					844:848	the outermost layer	830:848	the outermost layer of the material	830:864	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	5	6	theme	more	874:877	arg1	waves					895:899	more electromagnetic waves	874:899	more electromagnetic waves	874:899	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	3	7	theme	Ti3C2Tx/Fe3O4	388:400	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	7	theme	Ti3C2Tx/Fe3O4	388:400	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	7	theme	Ti3C2Tx/Fe3O4	388:400	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	8	theme	BC	425:426	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	8	theme	BC	425:426	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	8	theme	BC	425:426	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	9	theme	BC/Fe3O4	564:571	arg1	layers					554:559	layers	554:559	layers of BC/Fe3O4	554:571	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	6	10	theme	shielding	981:989	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	10	theme	shielding	981:989	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	3	11	theme	&	402:402	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	11	theme	&	402:402	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	11	theme	&	402:402	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	1	12	from	problem	180:186	arg1	society					198:204	society	198:204	society	198:204	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	8	13	theme	EMI	1272:1274	arg1	films					1286:1290	high-performance EMI shielding films	1255:1290	high-performance EMI shielding films	1255:1290	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	6	14	theme	45 μm	1055:1059	arg1	thickness					1061:1069	45 μm thickness	1055:1069	45 μm thickness	1055:1069	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	3	15	theme	layers	554:559	arg1	layers					581:586	the layers	577:586	the layers of Ti3C2Tx/Fe3O4	577:603	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	15	theme	layers	554:559	arg1	number					544:549	the number	540:549	the number of layers of BC/Fe3O4	540:571	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	8	16	theme	new	1228:1230	arg1	strategy					1232:1239	a new strategy	1226:1239	a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties	1226:1339	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	3	17	theme	hydrophobic	474:484	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	17	theme	hydrophobic	474:484	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	17	theme	hydrophobic	474:484	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	18	theme	MXene	382:386	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	18	theme	MXene	382:386	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	18	theme	MXene	382:386	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	7	19	dep	show	1103:1106	arg1	flexibility					1160:1170	flexibility	1160:1170	flexibility	1160:1170	What's more, the SBTFX-Y films show excellent mechanical properties, hydrophobicity and flexibility.					
37270119	7	19	dep	show	1103:1106	arg1	hydrophobicity					1141:1154	hydrophobicity	1141:1154	hydrophobicity	1141:1154	What's more, the SBTFX-Y films show excellent mechanical properties, hydrophobicity and flexibility.					
37270119	1	20	theme	Electromagnetic	128:142	arg1	EM					145:146	EM	145:146	EM	145:146	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	1	20	theme	Electromagnetic	128:142	arg1	pollution					149:157	Electromagnetic (EM) pollution	128:157	Electromagnetic (EM) pollution	128:157	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	3	21	theme	electromagnetic	486:500	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	21	theme	electromagnetic	486:500	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	21	theme	electromagnetic	486:500	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	0	22	theme	cellulose/Fe3O4/methyltrimethoxylsilane	16:54	arg1	film					65:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film	0:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.	0:126	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	6	23	theme	68 dB	1010:1014	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	23	theme	68 dB	1010:1014	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	5	24	theme	material	857:864	arg1	waves					895:899	more electromagnetic waves	874:899	more electromagnetic waves	874:899	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	5	24	theme	material	857:864	arg1	layer					844:848	the outermost layer	830:848	the outermost layer of the material	830:864	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	0	25	theme	MXene/bacterial	0:14	arg1	film					65:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film	0:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.	0:126	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	6	26	theme	EMI	976:978	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	26	theme	EMI	976:978	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	3	27	theme	Ti3C2Tx/Fe3O4	591:603	arg1	layers					581:586	the layers	577:586	the layers of Ti3C2Tx/Fe3O4	577:603	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	27	theme	Ti3C2Tx/Fe3O4	591:603	arg1	number					544:549	the number	540:549	the number of layers of BC/Fe3O4	540:571	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	1	28	theme	human	220:224	arg1	lives					226:230	human lives	220:230	human lives	220:230	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	3	29	theme	bacterial	404:412	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	29	theme	bacterial	404:412	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	29	theme	bacterial	404:412	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	5	30	theme	@	819:819	arg1	Fe3O4					820:824	BC@Fe3O4	817:824	BC@Fe3O4	817:824	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	1	31	dep	problem	180:186	arg1	affects					212:218	affects	212:218	affects human lives	212:230	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	3	32	theme	cellulose	414:422	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	32	theme	cellulose	414:422	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	32	theme	cellulose	414:422	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	6	33	theme	interference	962:973	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	33	theme	interference	962:973	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	2	34	theme	shielding	328:336	arg1	applications					338:349	electromagnetic interference (EMI) shielding applications	293:349	electromagnetic interference (EMI) shielding applications	293:349	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	7	35	theme	mechanical	1118:1127	arg1	properties					1129:1138	excellent mechanical properties	1108:1138	excellent mechanical properties	1108:1138	What's more, the SBTFX-Y films show excellent mechanical properties, hydrophobicity and flexibility.					
37270119	7	36	theme	excellent	1108:1116	arg1	properties					1129:1138	excellent mechanical properties	1108:1138	excellent mechanical properties	1108:1138	What's more, the SBTFX-Y films show excellent mechanical properties, hydrophobicity and flexibility.					
37270119	6	37	theme	electromagnetic	946:960	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	37	theme	electromagnetic	946:960	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	5	38	theme	outermost	834:842	arg1	waves					895:899	more electromagnetic waves	874:899	more electromagnetic waves	874:899	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	5	38	theme	outermost	834:842	arg1	layer					844:848	the outermost layer	830:848	the outermost layer of the material	830:864	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	3	39	theme	flexible	465:472	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	39	theme	flexible	465:472	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	39	theme	flexible	465:472	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	40	theme	shielding	502:510	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	40	theme	shielding	502:510	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	40	theme	shielding	502:510	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	0	41	theme	flexible	56:63	arg1	film					65:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film	0:68	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.	0:126	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	6	42	theme	maximum	938:944	arg1	efficiency					991:1000	The maximum electromagnetic interference (EMI) shielding efficiency	934:1000	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB	934:1014	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	6	42	theme	maximum	938:944	arg1	SE					1003:1004	SE	1003:1004	SE	1003:1004	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	3	43	theme	MTMS	459:462	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	43	theme	MTMS	459:462	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	43	theme	MTMS	459:462	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	8	44	theme	high-performance	1255:1270	arg1	films					1286:1290	high-performance EMI shielding films	1255:1290	high-performance EMI shielding films	1255:1290	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	8	45	theme	unique	1177:1182	arg1	structure					1195:1203	The unique stratified structure	1173:1203	The unique stratified structure of the film	1173:1215	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	0	46	with	film	65:68	arg1	hydrophobic					75:85	hydrophobic	75:85	hydrophobic	75:85	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	3	47	theme	film	512:515	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	47	theme	film	512:515	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	47	theme	film	512:515	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	0	48	theme	effective	91:99	arg1	shielding					117:125	effective electromagnetic shielding	91:125	effective electromagnetic shielding	91:125	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	8	49	theme	stratified	1184:1193	arg1	structure					1195:1203	The unique stratified structure	1173:1203	The unique stratified structure of the film	1173:1215	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	2	50	theme	strong	252:257	arg1	materials					279:287	strong and highly flexible materials	252:287	strong and highly flexible materials	252:287	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	8	51	theme	shielding	1276:1284	arg1	films					1286:1290	high-performance EMI shielding films	1255:1290	high-performance EMI shielding films	1255:1290	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	3	52	theme	/Fe3O4&Methyltrimethoxysilane	428:456	arg1	Y					533:533	Y	533:533	Y	533:533	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	52	theme	/Fe3O4&Methyltrimethoxysilane	428:456	arg1	X					527:527	X	527:527	X	527:527	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	3	52	theme	/Fe3O4&Methyltrimethoxysilane	428:456	arg1	SBTFX-Y					518:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y	380:524	Herein, a MXene Ti3C2Tx/Fe3O4 & bacterial cellulose (BC)/Fe3O4&Methyltrimethoxysilane (MTMS) flexible hydrophobic electromagnetic shielding film (SBTFX-Y, X and Y were the number of layers of BC/Fe3O4 and the layers of Ti3C2Tx/Fe3O4), was fabricated.					
37270119	4	53	theme	polarization	705:716	arg1	relaxation					718:727	polarization relaxation	705:727	polarization relaxation	705:727	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	4	54	theme	large	669:673	arg1	waves					691:695	radio waves	685:695	radio waves	685:695	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	4	54	theme	large	669:673	arg1	amount					675:680	a large amount	667:680	a large amount of radio waves	667:695	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	2	55	theme	electromagnetic	293:307	arg1	applications					338:349	electromagnetic interference (EMI) shielding applications	293:349	electromagnetic interference (EMI) shielding applications	293:349	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	4	56	theme	conduction	733:742	arg1	loss					744:747	conduction loss	733:747	conduction loss	733:747	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	5	57	theme	waves	810:814	arg1	reflectance					779:789	its extremely low reflectance	761:789	its extremely low reflectance of electromagnetic waves	761:814	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37270119	6	58	theme	composite	1037:1045	arg1	film					1047:1050	the composite film	1033:1050	the composite film at 45 μm thickness	1033:1069	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	1	59	theme	serious	172:178	arg1	problem					180:186	a serious problem	170:186	a serious problem in modern society as it affects human lives	170:230	Electromagnetic (EM) pollution has become a serious problem in modern society as it affects human lives.					
37270119	8	60	theme	mechanical	1319:1328	arg1	properties					1330:1339	mechanical properties	1319:1339	mechanical properties	1319:1339	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	4	61	theme	MXene	645:649	arg1	Ti3C2Tx					651:657	MXene Ti3C2Tx	645:657	MXene Ti3C2Tx	645:657	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	2	62	theme	materials	279:287	arg1	urgent					364:369	urgent	364:369	urgent	364:369	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	2	62	theme	materials	279:287	arg1	fabrication					237:247	The fabrication	233:247	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications	233:349	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	6	63	from	thickness	1061:1069	arg1	film					1047:1050	the composite film	1033:1050	the composite film at 45 μm thickness	1033:1069	The maximum electromagnetic interference (EMI) shielding efficiency (SE) of 68 dB was achieved for the composite film at 45 μm thickness.					
37270119	4	64	theme	radio	685:689	arg1	waves					691:695	radio waves	685:695	radio waves	685:695	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	8	65	theme	film	1212:1215	arg1	structure					1195:1203	The unique stratified structure	1173:1203	The unique stratified structure of the film	1173:1215	The unique stratified structure of the film provides a new strategy for designing high-performance EMI shielding films with excellent surface and mechanical properties.					
37270119	4	66	theme	prepared	630:637	arg1	film					639:642	the prepared film	626:642	the prepared film	626:642	In the prepared film, MXene Ti3C2Tx absorbs a large amount of radio waves through polarization relaxation and conduction loss.					
37270119	0	67	theme	electromagnetic	101:115	arg1	shielding					117:125	effective electromagnetic shielding	91:125	effective electromagnetic shielding	91:125	MXene/bacterial cellulose/Fe3O4/methyltrimethoxylsilane flexible film with hydrophobic for effective electromagnetic shielding.					
37270119	2	68	theme	flexible	270:277	arg1	materials					279:287	strong and highly flexible materials	252:287	strong and highly flexible materials	252:287	The fabrication of strong and highly flexible materials for electromagnetic interference (EMI) shielding applications is extremely urgent.					
37270119	5	69	theme	BC	817:818	arg1	Fe3O4					820:824	BC@Fe3O4	817:824	BC@Fe3O4	817:824	Because of its extremely low reflectance of electromagnetic waves, BC@Fe3O4, as the outermost layer of the material, allows more electromagnetic waves to incident inside the material.					
37173013	5	0	theme	delivery	1568:1575	arg1	system					1577:1582	low-leakage drug delivery system	1551:1582	low-leakage drug delivery system	1551:1582	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	3	1	theme	hydrolyzed	714:723	arg1	starch					725:730	the enzymatic hydrolyzed starch	700:730	the enzymatic hydrolyzed starch	700:730	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	2	theme	porous	968:973	arg1	surface					975:981	The porous surface	964:981	The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein	964:1066	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	5	3	theme	natural	1473:1479	arg1	material					1433:1440	The wall material	1424:1440	The wall material	1424:1440	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	3	theme	natural	1473:1479	arg1	friendly					1501:1508	natural and environmentally friendly	1473:1508	natural and environmentally friendly	1473:1508	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	3	theme	natural	1473:1479	arg1	method					1462:1467	the preparation method	1446:1467	the preparation method	1446:1467	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	0	4	theme	sunscreen	88:96	arg1	agents					98:103	organic sunscreen agents	80:103	organic sunscreen agents	80:103	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	3	5	theme	whey	1055:1058	arg1	protein					1060:1066	whey protein	1055:1066	whey protein	1055:1066	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	5	6	theme	good	1522:1525	arg1	prospect					1539:1546	a good application prospect	1520:1546	a good application prospect	1520:1546	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	4	7	theme	irradiation	1390:1400	arg1	intensity					1402:1410	the irradiation intensity	1386:1410	the irradiation intensity of 25 w/m2	1386:1421	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	0	8	dep	protection	116:125	arg1	performance					127:137	performance	127:137	performance	127:137	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	1	9	theme	SPF	273:275	arg1	value					277:281	the SPF value	269:281	the SPF value	269:281	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	5	10	theme	application	1527:1537	arg1	prospect					1539:1546	a good application prospect	1520:1546	a good application prospect	1520:1546	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	4	11	theme	SPF	1217:1219	arg1	value					1221:1225	the SPF value	1213:1225	the SPF value of the lotion containing sunscreen microcapsules	1213:1274	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	12	theme	lotion	1234:1239	arg1	value					1221:1225	the SPF value	1213:1225	the SPF value of the lotion containing sunscreen microcapsules	1213:1274	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	13	dep	lotion	1144:1149	arg1	containing					1151:1160	containing	1151:1160	containing the same amount of sunscreen	1151:1189	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	13	dep	lotion	1144:1149	arg1	encapsulated					1199:1210	encapsulated	1199:1210	encapsulated	1199:1210	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	3	14	theme	specific	827:834	arg1	volume					836:841	the specific volume	823:841	the specific volume	823:841	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	15	theme	porous	741:746	arg1	structure					748:756	a porous structure	739:756	a porous structure	739:756	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	16	theme	starch	990:995	arg1	surface					975:981	The porous surface	964:981	The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein	964:1066	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	2	17	theme	wall	390:393	arg1	materials					395:403	wall materials	390:403	wall materials	390:403	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	17	theme	wall	390:393	arg1	starch					363:368	modified porous corn starch	342:368	modified porous corn starch	342:368	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	17	theme	wall	390:393	arg1	protein					379:385	whey protein	374:385	whey protein	374:385	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	0	18	theme	UV	113:114	arg1	protection					116:125	its UV protection performance and stability	109:151	protection	116:125	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	0	19	theme	starch	39:44	arg1	microcapsules					56:68	enzymolysis porous corn starch composite microcapsules	15:68	enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability	15:151	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	4	20	theme	sunscreen	1181:1189	arg1	sunscreen					1181:1189	sunscreen	1181:1189	sunscreen	1181:1189	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	20	theme	sunscreen	1181:1189	arg1	amount					1171:1176	the same amount	1162:1176	the same amount of sunscreen	1162:1189	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	1	21	theme	natural	171:177	arg1	microcapsule					213:224	a natural composite wall material sunscreen microcapsule	169:224	a natural composite wall material sunscreen microcapsule	169:224	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	5	22	theme	low-leakage	1551:1561	arg1	system					1577:1582	low-leakage drug delivery system	1551:1582	low-leakage drug delivery system	1551:1582	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	1	23	theme	composite	179:187	arg1	microcapsule					213:224	a natural composite wall material sunscreen microcapsule	169:224	a natural composite wall material sunscreen microcapsule	169:224	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	1	24	theme	wall	189:192	arg1	microcapsule					213:224	a natural composite wall material sunscreen microcapsule	169:224	a natural composite wall material sunscreen microcapsule	169:224	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	0	25	theme	porous	27:32	arg1	microcapsules					56:68	enzymolysis porous corn starch composite microcapsules	15:68	enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability	15:151	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	3	26	theme	X-ray	763:767	arg1	pattern					781:787	its X-ray diffraction pattern	759:787	its X-ray diffraction pattern	759:787	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	5	27	theme	wall	1428:1431	arg1	material					1433:1440	The wall material	1424:1440	The wall material	1424:1440	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	27	theme	wall	1428:1431	arg1	friendly					1501:1508	natural and environmentally friendly	1473:1508	natural and environmentally friendly	1473:1508	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	27	theme	wall	1428:1431	arg1	method					1462:1467	the preparation method	1446:1467	the preparation method	1446:1467	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	3	28	dep	increased	867:875	arg1	compared					915:922	compared	915:922	compared with those before enzymatic hydrolyzed	915:961	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	4	29	theme	microcapsules	1334:1346	arg1	photostability					1306:1319	the photostability	1302:1319	the photostability of sunscreen microcapsules	1302:1346	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	30	theme	penetration	1085:1095	arg1	rate					1097:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	1	31	theme	material	194:201	arg1	microcapsule					213:224	a natural composite wall material sunscreen microcapsule	169:224	a natural composite wall material sunscreen microcapsule	169:224	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	0	32	theme	enzymolysis	15:25	arg1	microcapsules					56:68	enzymolysis porous corn starch composite microcapsules	15:68	enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability	15:151	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	4	33	theme	sunscreen	1252:1260	arg1	microcapsules					1262:1274	sunscreen microcapsules	1252:1274	sunscreen microcapsules	1252:1274	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	2	34	theme	benzoic	465:471	arg1	acid					473:476	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid	427:476	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	1	35	theme	sunscreen	203:211	arg1	microcapsule					213:224	a natural composite wall material sunscreen microcapsule	169:224	a natural composite wall material sunscreen microcapsule	169:224	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	2	36	theme	hexyl	478:482	arg1	ester					484:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	36	theme	hexyl	478:482	arg1	agents					420:425	the sunscreen agents	406:425	the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate	406:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	4	37	contain	containing	1241:1250	arg2	microcapsules					1262:1274	sunscreen microcapsules	1252:1274	sunscreen microcapsules	1252:1274	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	37	contain	containing	1241:1250	arg1	lotion					1234:1239	the lotion	1230:1239	the lotion containing sunscreen microcapsules	1230:1274	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	38	theme	120 h	1069:1073	arg1	rate					1097:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	2	39	theme	sunscreen	410:418	arg1	ester					484:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	39	theme	sunscreen	410:418	arg1	methoxycinnamate					505:520	ethylhexyl methoxycinnamate	494:520	ethylhexyl methoxycinnamate	494:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	39	theme	sunscreen	410:418	arg1	agents					420:425	the sunscreen agents	406:425	the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate	406:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	0	40	theme	corn	34:37	arg1	microcapsules					56:68	enzymolysis porous corn starch composite microcapsules	15:68	enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability	15:151	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	1	41	theme	embedded	309:316	arg1	agents					328:333	the embedded sunscreen agents	305:333	the embedded sunscreen agents	305:333	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	2	42	theme	acid	473:476	arg1	ester					484:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	42	theme	acid	473:476	arg1	agents					420:425	the sunscreen agents	406:425	the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate	406:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	3	43	theme	diffraction	769:779	arg1	pattern					781:787	its X-ray diffraction pattern	759:787	its X-ray diffraction pattern	759:787	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	4	44	theme	sunscreen	1075:1083	arg1	rate					1097:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate	1069:1100	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	0	45	theme	microcapsules	56:68	arg1	Preparation					0:10	Preparation	0:10	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.	0:152	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	1	46	theme	sunscreen	318:326	arg1	agents					328:333	the embedded sunscreen agents	305:333	the embedded sunscreen agents	305:333	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	5	47	theme	drug	1563:1566	arg1	system					1577:1582	low-leakage drug delivery system	1551:1582	low-leakage drug delivery system	1551:1582	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	48	contain	have	1515:1518	arg1	material					1433:1440	The wall material	1424:1440	The wall material	1424:1440	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	48	contain	have	1515:1518	arg1	friendly					1501:1508	natural and environmentally friendly	1473:1508	natural and environmentally friendly	1473:1508	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	48	contain	have	1515:1518	arg1	method					1462:1467	the preparation method	1446:1467	the preparation method	1446:1467	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	48	contain	have	1515:1518	arg2	prospect					1539:1546	a good application prospect	1520:1546	a good application prospect	1520:1546	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	3	49	theme	embedding	599:607	arg1	rate					609:612	The embedding rate	595:612	The embedding rate of the obtained sunscreen microcapsules	595:652	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	49	theme	embedding	599:607	arg1	%					664:664	32.71 %	658:664	32.71 %	658:664	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	2	50	theme	corn	358:361	arg1	materials					395:403	wall materials	390:403	wall materials	390:403	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	50	theme	corn	358:361	arg1	starch					363:368	modified porous corn starch	342:368	modified porous corn starch	342:368	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	50	theme	corn	358:361	arg1	protein					379:385	whey protein	374:385	whey protein	374:385	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	0	51	theme	composite	46:54	arg1	microcapsules					56:68	enzymolysis porous corn starch composite microcapsules	15:68	enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability	15:151	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	1	52	theme	agents	328:333	arg1	photostability					287:300	photostability	287:300	photostability	287:300	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	1	52	theme	agents	328:333	arg1	value					277:281	the SPF value	269:281	the SPF value	269:281	In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents.					
37173013	2	53	dep	agents	420:425	arg1	ester					484:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester	427:488	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	53	dep	agents	420:425	arg1	methoxycinnamate					505:520	ethylhexyl methoxycinnamate	494:520	ethylhexyl methoxycinnamate	494:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	53	dep	agents	420:425	arg1	agents					420:425	the sunscreen agents	406:425	the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate	406:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	5	54	theme	preparation	1450:1460	arg1	material					1433:1440	The wall material	1424:1440	The wall material	1424:1440	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	54	theme	preparation	1450:1460	arg1	friendly					1501:1508	natural and environmentally friendly	1473:1508	natural and environmentally friendly	1473:1508	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	54	theme	preparation	1450:1460	arg1	method					1462:1467	the preparation method	1446:1467	the preparation method	1446:1467	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	2	55	theme	porous	351:356	arg1	materials					395:403	wall materials	390:403	wall materials	390:403	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	55	theme	porous	351:356	arg1	starch					363:368	modified porous corn starch	342:368	modified porous corn starch	342:368	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	55	theme	porous	351:356	arg1	protein					379:385	whey protein	374:385	whey protein	374:385	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	5	56	theme	environmentally	1485:1499	arg1	material					1433:1440	The wall material	1424:1440	The wall material	1424:1440	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	56	theme	environmentally	1485:1499	arg1	friendly					1501:1508	natural and environmentally friendly	1473:1508	natural and environmentally friendly	1473:1508	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	5	56	theme	environmentally	1485:1499	arg1	method					1462:1467	the preparation method	1446:1467	the preparation method	1446:1467	The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.					
37173013	3	57	theme	microcapsules	640:652	arg1	rate					609:612	The embedding rate	595:612	The embedding rate of the obtained sunscreen microcapsules	595:652	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	57	theme	microcapsules	640:652	arg1	%					664:664	32.71 %	658:664	32.71 %	658:664	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	4	58	theme	same	1166:1169	arg1	sunscreen					1181:1189	sunscreen	1181:1189	sunscreen	1181:1189	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	4	58	theme	same	1166:1169	arg1	amount					1171:1176	the same amount	1162:1176	the same amount of sunscreen	1162:1189	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	2	59	theme	modified	342:349	arg1	materials					395:403	wall materials	390:403	wall materials	390:403	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	59	theme	modified	342:349	arg1	starch					363:368	modified porous corn starch	342:368	modified porous corn starch	342:368	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	59	theme	modified	342:349	arg1	protein					379:385	whey protein	374:385	whey protein	374:385	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	3	60	theme	average	674:680	arg1	size					682:685	the average size	670:685	the average size	670:685	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	61	theme	oil	847:849	arg1	rate					862:865	oil absorption rate	847:865	oil absorption rate	847:865	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	62	dep	%	664:664	arg1	surface					975:981	The porous surface	964:981	The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein	964:1066	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	0	63	theme	organic	80:86	arg1	agents					98:103	organic sunscreen agents	80:103	organic sunscreen agents	80:103	Preparation of enzymolysis porous corn starch composite microcapsules embedding organic sunscreen agents and its UV protection performance and stability.					
37173013	4	64	theme	w/m2	1418:1421	arg1	intensity					1402:1410	the irradiation intensity	1386:1410	the irradiation intensity of 25 w/m2	1386:1421	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
37173013	3	65	theme	obtained	621:628	arg1	microcapsules					640:652	the obtained sunscreen microcapsules	617:652	the obtained sunscreen microcapsules	617:652	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	66	theme	absorption	851:860	arg1	rate					862:865	oil absorption rate	847:865	oil absorption rate	847:865	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	2	67	theme	ethylhexyl	494:503	arg1	methoxycinnamate					505:520	ethylhexyl methoxycinnamate	494:520	ethylhexyl methoxycinnamate	494:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	67	theme	ethylhexyl	494:503	arg1	agents					420:425	the sunscreen agents	406:425	the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate	406:520	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	3	68	theme	enzymatic	704:712	arg1	starch					725:730	the enzymatic hydrolyzed starch	700:730	the enzymatic hydrolyzed starch	700:730	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	3	69	theme	sunscreen	630:638	arg1	microcapsules					640:652	the obtained sunscreen microcapsules	617:652	the obtained sunscreen microcapsules	617:652	The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein.					
37173013	2	70	theme	whey	374:377	arg1	materials					395:403	wall materials	390:403	wall materials	390:403	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	70	theme	whey	374:377	arg1	starch					363:368	modified porous corn starch	342:368	modified porous corn starch	342:368	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	2	70	theme	whey	374:377	arg1	protein					379:385	whey protein	374:385	whey protein	374:385	Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification.					
37173013	4	71	theme	sunscreen	1324:1332	arg1	microcapsules					1334:1346	sunscreen microcapsules	1324:1346	sunscreen microcapsules	1324:1346	120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m2.					
36731707	3	0	theme	acid	561:564	arg1	cross-linking					512:524	the simultaneous cross-linking	495:524	the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions	495:584	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	4	1	theme	SCTF	613:616	arg1	cryogels					618:625	the prepared SCTF cryogels	600:625	the prepared SCTF cryogels	600:625	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	7	2	theme	chemodynamic	1133:1144	arg1	CDT					1155:1157	CDT	1155:1157	CDT	1155:1157	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	7	2	theme	chemodynamic	1133:1144	arg1	therapy					1146:1152	chemodynamic therapy	1133:1152	chemodynamic therapy (CDT)	1133:1158	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	9	3	theme	developed	1462:1470	arg1	materials					1482:1490	the developed composite materials	1458:1490	the developed composite materials	1458:1490	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	1	4	theme	Uncontrolled	137:148	arg1	cause					171:175	a main cause	164:175	a main cause of pre-hospital death	164:197	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	1	4	theme	Uncontrolled	137:148	arg1	hemorrhage					150:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	9	5	from	applications	1575:1586	arg1	future					1595:1600	future	1595:1600	future	1595:1600	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	0	6	theme	Alginate	0:7	arg1	cryogels					28:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	4	7	theme	Fe3+/SA-based	689:701	arg1	skeleton					706:713	Fe3+/SA-based 3D skeleton	689:713	Fe3+/SA-based 3D skeleton for collagen (CA)	689:731	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	9	8	theme	composite	1472:1480	arg1	materials					1482:1490	the developed composite materials	1458:1490	the developed composite materials	1458:1490	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	4	9	theme	phenolic	660:667	arg1	networks					669:676	Fe3+/TA-based metal phenolic networks	640:676	Fe3+/TA-based metal phenolic networks (MPNs)	640:683	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	4	9	theme	phenolic	660:667	arg1	MPNs					679:682	MPNs	679:682	MPNs	679:682	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	7	10	theme	photothermal	1105:1116	arg1	PTT					1127:1129	PTT	1127:1129	PTT	1127:1129	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	7	10	theme	photothermal	1105:1116	arg1	therapy					1118:1124	the synergistic photothermal therapy	1089:1124	the synergistic photothermal therapy (PTT)	1089:1130	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	2	11	theme	fast	331:334	arg1	hemostasis					336:345	fast hemostasis	331:345	fast hemostasis	331:345	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	5	12	theme	TA	880:881	arg1	activity					815:822	photothermal-enhanced Fenton activity	786:822	photothermal-enhanced Fenton activity	786:822	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	12	theme	TA	880:881	arg1	effect					778:783	photothermal effect	765:783	photothermal effect	765:783	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	12	theme	TA	880:881	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	6	13	theme	in	983:984	arg1	assays					1004:1009	in vitro and in vivo assays	983:1009	in vitro and in vivo assays	983:1009	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	2	14	theme	pre-hospital	254:265	arg1	treatment					277:285	pre-hospital emergency treatment	254:285	pre-hospital emergency treatment	254:285	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	5	15	theme	Fe2+	887:890	arg1	activity					815:822	photothermal-enhanced Fenton activity	786:822	photothermal-enhanced Fenton activity	786:822	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	15	theme	Fe2+	887:890	arg1	effect					778:783	photothermal effect	765:783	photothermal effect	765:783	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	15	theme	Fe2+	887:890	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	8	16	theme	healing-accelerating	1327:1346	arg1	effects					1348:1354	their outstanding healing-accelerating effects	1309:1354	their outstanding healing-accelerating effects	1309:1354	Eventually, their outstanding healing-accelerating effects were confirmed via animal experiments, which were attributed to the presence of CA and TA.					
36731707	2	17	theme	dressings	241:249	arg1	importance					210:219	the importance	206:219	the importance of hemostatic wound dressings in pre-hospital emergency treatment	206:285	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	9	18	theme	wound	1547:1551	arg1	dressing					1553:1560	multifunctional wound dressing	1531:1560	multifunctional wound dressing	1531:1560	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	6	19	theme	intrinsic	958:966	arg1	porosity					973:980	the intrinsic high porosity	954:980	the intrinsic high porosity	954:980	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	6	20	dep	in	983:984	arg1	vitro					986:990	vitro	986:990	vitro	986:990	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	2	21	theme	novel	288:292	arg1	materials					304:312	novel composite materials	288:312	novel composite materials	288:312	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	5	22	theme	photothermal	765:776	arg1	effect					778:783	photothermal effect	765:783	photothermal effect	765:783	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	6	23	theme	SCTF	1029:1032	arg1	cryogels					1034:1041	SCTF cryogels	1029:1041	SCTF cryogels	1029:1041	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	4	24	theme	collagen	719:726	arg1	CA					729:730	collagen (CA)	719:731	collagen (CA)	719:731	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	7	25	theme	cryogels	1261:1268	arg1	efficacy					1244:1251	the bactericidal efficacy	1227:1251	the bactericidal efficacy of SCTF cryogels	1227:1268	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	1	26	theme	pre-hospital	180:191	arg1	death					193:197	pre-hospital death	180:197	pre-hospital death	180:197	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	0	27	theme	accelerated	110:120	arg1	healing					128:134	accelerated wound healing	110:134	accelerated wound healing	110:134	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	6	28	contain	possessed	1043:1051	arg1	cryogels					1034:1041	SCTF cryogels	1029:1041	SCTF cryogels	1029:1041	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	6	28	contain	possessed	1043:1051	arg2	capacity					1069:1076	good hemostatic capacity	1053:1076	good hemostatic capacity	1053:1076	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	7	29	theme	bactericidal	1231:1242	arg1	efficacy					1244:1251	the bactericidal efficacy	1227:1251	the bactericidal efficacy of SCTF cryogels	1227:1268	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	5	30	theme	dual-responsive	844:858	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	2	31	theme	wound	410:414	arg1	healing					416:422	wound healing	410:422	wound healing	410:422	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	3	32	theme	sodium	529:534	arg1	SA					546:547	SA	546:547	SA	546:547	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	3	32	theme	sodium	529:534	arg1	alginate					536:543	sodium alginate	529:543	sodium alginate (SA)	529:548	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	0	33	theme	photothermal	15:26	arg1	cryogels					28:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	2	34	with	ablation	370:377	arg1	resistance					395:404	negligible resistance	384:404	negligible resistance	384:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	1	35	theme	main	166:169	arg1	cause					171:175	a main cause	164:175	a main cause of pre-hospital death	164:197	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	1	35	theme	main	166:169	arg1	hemorrhage					150:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	5	36	theme	Fenton	808:813	arg1	activity					815:822	photothermal-enhanced Fenton activity	786:822	photothermal-enhanced Fenton activity	786:822	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	7	37	theme	pH/photothermal	1164:1178	arg1	chemo-therapy					1191:1203	pH/photothermal responsive chemo-therapy	1164:1203	pH/photothermal responsive chemo-therapy	1164:1203	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	6	38	theme	hemostatic	1058:1067	arg1	capacity					1069:1076	good hemostatic capacity	1053:1076	good hemostatic capacity	1053:1076	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	3	39	theme	multifunctional	446:460	arg1	cryogels					467:474	multifunctional SCTF cryogels	446:474	multifunctional SCTF cryogels	446:474	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	0	40	theme	antibacterial	71:83	arg1	therapy					98:104	enhanced antibacterial chemodynamic therapy	62:104	enhanced antibacterial chemodynamic therapy	62:104	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	2	41	theme	negligible	384:393	arg1	resistance					395:404	negligible resistance	384:404	negligible resistance	384:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	2	42	theme	hemostatic	224:233	arg1	dressings					241:249	hemostatic wound dressings	224:249	hemostatic wound dressings	224:249	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	2	43	with	healing	416:422	arg1	resistance					395:404	negligible resistance	384:404	negligible resistance	384:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	2	44	dep	hemostasis	336:345	arg1	acceleration					424:435	acceleration	424:435	acceleration	424:435	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	3	45	theme	tannic	554:559	arg1	acid					561:564	tannic acid	554:564	tannic acid (TA)	554:569	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	3	45	theme	tannic	554:559	arg1	TA					567:568	TA	567:568	TA	567:568	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	3	46	theme	Fe3+	576:579	arg1	ions					581:584	Fe3+ ions	576:584	Fe3+ ions	576:584	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	2	47	from	importance	210:219	arg1	treatment					277:285	pre-hospital emergency treatment	254:285	pre-hospital emergency treatment	254:285	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	4	48	theme	prepared	604:611	arg1	cryogels					618:625	the prepared SCTF cryogels	600:625	the prepared SCTF cryogels	600:625	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	1	49	theme	death	193:197	arg1	cause					171:175	a main cause	164:175	a main cause of pre-hospital death	164:197	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	1	49	theme	death	193:197	arg1	hemorrhage					150:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage	137:159	Uncontrolled hemorrhage is a main cause of pre-hospital death.					
36731707	2	50	theme	synergistic	348:358	arg1	ablation					370:377	synergistic bacterial ablation	348:377	synergistic bacterial ablation with negligible resistance	348:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	6	51	theme	in	996:997	arg1	assays					1004:1009	in vitro and in vivo assays	983:1009	in vitro and in vivo assays	983:1009	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	3	52	with	cross-linking	512:524	arg1	ions					581:584	Fe3+ ions	576:584	Fe3+ ions	576:584	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	9	53	theme	new	1504:1506	arg1	strategy					1508:1515	new strategy	1504:1515	new strategy	1504:1515	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	4	54	theme	metal	654:658	arg1	networks					669:676	Fe3+/TA-based metal phenolic networks	640:676	Fe3+/TA-based metal phenolic networks (MPNs)	640:683	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	4	54	theme	metal	654:658	arg1	MPNs					679:682	MPNs	679:682	MPNs	679:682	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	2	55	theme	emergency	267:275	arg1	treatment					277:285	pre-hospital emergency treatment	254:285	pre-hospital emergency treatment	254:285	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	9	56	theme	multifunctional	1531:1545	arg1	dressing					1553:1560	multifunctional wound dressing	1531:1560	multifunctional wound dressing	1531:1560	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	6	57	theme	high	968:971	arg1	porosity					973:980	the intrinsic high porosity	954:980	the intrinsic high porosity	954:980	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	7	58	theme	synergistic	1093:1103	arg1	PTT					1127:1129	PTT	1127:1129	PTT	1127:1129	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	7	58	theme	synergistic	1093:1103	arg1	therapy					1118:1124	the synergistic photothermal therapy	1089:1124	the synergistic photothermal therapy (PTT)	1089:1130	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	5	59	with	endowed	739:745	arg1	activity					815:822	photothermal-enhanced Fenton activity	786:822	photothermal-enhanced Fenton activity	786:822	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	59	with	endowed	739:745	arg1	effect					778:783	photothermal effect	765:783	photothermal effect	765:783	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	59	with	endowed	739:745	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	8	60	theme	outstanding	1315:1325	arg1	effects					1348:1354	their outstanding healing-accelerating effects	1309:1354	their outstanding healing-accelerating effects	1309:1354	Eventually, their outstanding healing-accelerating effects were confirmed via animal experiments, which were attributed to the presence of CA and TA.					
36731707	7	61	theme	responsive	1180:1189	arg1	chemo-therapy					1191:1203	pH/photothermal responsive chemo-therapy	1164:1203	pH/photothermal responsive chemo-therapy	1164:1203	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	2	62	theme	composite	294:302	arg1	materials					304:312	novel composite materials	288:312	novel composite materials	288:312	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	6	63	theme	good	1053:1056	arg1	capacity					1069:1076	good hemostatic capacity	1053:1076	good hemostatic capacity	1053:1076	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	6	64	dep	in	996:997	arg1	vivo					999:1002	vivo	999:1002	vivo	999:1002	Due to the intrinsic high porosity, in vitro and in vivo assays demonstrated that SCTF cryogels possessed good hemostatic capacity.					
36731707	0	65	theme	chemodynamic	85:96	arg1	therapy					98:104	enhanced antibacterial chemodynamic therapy	62:104	enhanced antibacterial chemodynamic therapy	62:104	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	9	66	theme	clinical	1566:1573	arg1	applications					1575:1586	clinical applications	1566:1586	clinical applications in the future	1566:1600	Therefore, the developed composite materials could offer new strategy on exploiting multifunctional wound dressing for clinical applications in the future.					
36731707	4	67	theme	3D	703:704	arg1	skeleton					706:713	Fe3+/SA-based 3D skeleton	689:713	Fe3+/SA-based 3D skeleton for collagen (CA)	689:731	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	7	68	theme	SCTF	1256:1259	arg1	cryogels					1261:1268	SCTF cryogels	1256:1268	SCTF cryogels	1256:1268	Moreover, the synergistic photothermal therapy (PTT), chemodynamic therapy (CDT) and pH/photothermal responsive chemo-therapy dramatically enhanced the bactericidal efficacy of SCTF cryogels both in vitro and in vivo.					
36731707	5	69	theme	antibacterial	923:935	arg1	capacity					937:944	the antibacterial capacity	919:944	the antibacterial capacity	919:944	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	2	70	with	hemostasis	336:345	arg1	resistance					395:404	negligible resistance	384:404	negligible resistance	384:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	8	71	theme	animal	1375:1380	arg1	experiments					1382:1392	animal experiments	1375:1392	animal experiments	1375:1392	Eventually, their outstanding healing-accelerating effects were confirmed via animal experiments, which were attributed to the presence of CA and TA.					
36731707	0	72	theme	wound	122:126	arg1	healing					128:134	accelerated wound healing	110:134	accelerated wound healing	110:134	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	3	73	theme	simultaneous	499:510	arg1	cross-linking					512:524	the simultaneous cross-linking	495:524	the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions	495:584	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	5	74	theme	pH/photothermal	828:842	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	5	75	theme	release	860:866	arg1	property					868:875	pH/photothermal dual-responsive release property	828:875	pH/photothermal dual-responsive release property	828:875	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	3	76	theme	alginate	536:543	arg1	cross-linking					512:524	the simultaneous cross-linking	495:524	the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions	495:584	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	5	77	theme	photothermal-enhanced	786:806	arg1	activity					815:822	photothermal-enhanced Fenton activity	786:822	photothermal-enhanced Fenton activity	786:822	MPNs endowed the cryogels with photothermal effect, photothermal-enhanced Fenton activity and pH/photothermal dual-responsive release property of TA and Fe2+, which were beneficial for the antibacterial capacity.					
36731707	8	78	theme	CA	1436:1437	arg1	presence					1424:1431	the presence	1420:1431	the presence of CA and TA	1420:1444	Eventually, their outstanding healing-accelerating effects were confirmed via animal experiments, which were attributed to the presence of CA and TA.					
36731707	0	79	theme	enhanced	62:69	arg1	therapy					98:104	enhanced antibacterial chemodynamic therapy	62:104	enhanced antibacterial chemodynamic therapy	62:104	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
36731707	3	80	theme	SCTF	462:465	arg1	cryogels					467:474	multifunctional SCTF cryogels	446:474	multifunctional SCTF cryogels	446:474	Herein, multifunctional SCTF cryogels were fabricated by the simultaneous cross-linking of sodium alginate (SA) and tannic acid (TA) with Fe3+ ions.					
36731707	2	81	theme	wound	235:239	arg1	dressings					241:249	hemostatic wound dressings	224:249	hemostatic wound dressings	224:249	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	8	82	theme	TA	1443:1444	arg1	presence					1424:1431	the presence	1420:1431	the presence of CA and TA	1420:1444	Eventually, their outstanding healing-accelerating effects were confirmed via animal experiments, which were attributed to the presence of CA and TA.					
36731707	2	83	theme	bacterial	360:368	arg1	ablation					370:377	synergistic bacterial ablation	348:377	synergistic bacterial ablation with negligible resistance	348:404	Given the importance of hemostatic wound dressings in pre-hospital emergency treatment, novel composite materials are required for fast hemostasis, synergistic bacterial ablation with negligible resistance and wound healing acceleration.					
36731707	4	84	theme	Fe3+/TA-based	640:652	arg1	networks					669:676	Fe3+/TA-based metal phenolic networks	640:676	Fe3+/TA-based metal phenolic networks (MPNs)	640:683	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	4	84	theme	Fe3+/TA-based	640:652	arg1	MPNs					679:682	MPNs	679:682	MPNs	679:682	As a result, the prepared SCTF cryogels consisted of Fe3+/TA-based metal phenolic networks (MPNs) and Fe3+/SA-based 3D skeleton for collagen (CA).					
36731707	0	85	theme	based	9:13	arg1	cryogels					28:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels	0:35	Alginate based photothermal cryogels boost ferrous-supply for enhanced antibacterial chemodynamic therapy and accelerated wound healing.					
35622280	6	0	theme	film	957:960	arg1	diffusion					962:970	film diffusion	957:970	film diffusion	957:970	The kinetic data for all the phenolic pollutants follow the pseudo-second-order model, and the rate was controlled by film diffusion.					
35622280	7	1	theme	phenolic	1030:1037	arg1	pollutants					1039:1048	phenolic pollutants	1030:1048	phenolic pollutants	1030:1048	Thermodynamic data revealed that the process of removing phenolic pollutants is spontaneous and endothermic.					
35622280	1	2	theme	consisting	182:191	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	2	theme	consisting	182:191	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	9	3	dep	78	1269:1270	arg1	to					1266:1267	to	1266:1267	to	1266:1267	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	0	4	theme	oxide	100:104	arg1	composite					106:114	reduced graphene oxide composite	83:114	reduced graphene oxide composite adsorbent for treatment of phenolic wastewater	83:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	5	5	theme	maximum	705:711	arg1	uptake					713:718	The maximum uptake	701:718	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol	701:769	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol was 702.853, 659.475, and 674.155 mg/g, respectively, at 25 ± 1 °C.					
35622280	5	5	theme	maximum	705:711	arg1	702.853					775:781	702.853	775:781	702.853	775:781	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol was 702.853, 659.475, and 674.155 mg/g, respectively, at 25 ± 1 °C.					
35622280	9	6	theme	synthetic	1221:1229	arg1	effluents					1242:1250	synthetic industrial effluents	1221:1250	synthetic industrial effluents	1221:1250	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	1	7	theme	reduced	193:199	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	7	theme	reduced	193:199	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	4	8	theme	isotherm	629:636	arg1	data					638:641	The isotherm data	625:641	The isotherm data	625:641	The isotherm data were more suitably fitted by the Langmuir isotherm model.					
35622280	2	9	from	solution	506:513	arg1	composite					464:472	the synthesized composite	448:472	the synthesized composite	448:472	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	9	from	solution	506:513	arg1	adsorbent					480:488	adsorbent	480:488	adsorbent	480:488	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	9	10	theme	industrial	1231:1240	arg1	effluents					1242:1250	synthetic industrial effluents	1221:1250	synthetic industrial effluents	1221:1250	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	10	11	theme	synthesized	1392:1402	arg1	composite					1404:1412	the synthesized composite	1388:1412	the synthesized composite	1388:1412	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	1	12	theme	phenolic	324:331	arg1	wastewater					333:342	phenolic wastewater	324:342	phenolic wastewater	324:342	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	0	13	theme	adsorbent	116:124	arg1	composite					106:114	reduced graphene oxide composite	83:114	reduced graphene oxide composite adsorbent for treatment of phenolic wastewater	83:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	3	14	theme	time	576:579	arg1	60 min					581:586	adsorption time 60 min	565:586	adsorption time 60 min	565:586	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	1	15	theme	wastewater	333:342	arg1	treatment					311:319	the treatment	307:319	the treatment of phenolic wastewater	307:342	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	8	16	used	used	1103:1106	arg2	composite					1086:1094	The composite	1082:1094	The composite	1082:1094	The composite can be used up to five cycles with a small reduction in the removal.					
35622280	10	17	theme	phenolic	1468:1475	arg1	pollutants					1477:1486	phenolic pollutants	1468:1486	phenolic pollutants from wastewater	1468:1502	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	6	18	theme	kinetic	843:849	arg1	data					851:854	The kinetic data	839:854	The kinetic data for all the phenolic pollutants	839:886	The kinetic data for all the phenolic pollutants follow the pseudo-second-order model, and the rate was controlled by film diffusion.					
35622280	2	19	theme	Batch	345:349	arg1	study					351:355	Batch study	345:355	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol)	345:427	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	1	20	theme	graphene	201:208	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	20	theme	graphene	201:208	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	8	21	from	reduction	1139:1147	arg1	removal					1156:1162	the removal	1152:1162	the removal	1152:1162	The composite can be used up to five cycles with a small reduction in the removal.					
35622280	1	22	theme	oxide-functionalized	210:229	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	22	theme	oxide-functionalized	210:229	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	8	23	dep	five	1114:1117	arg1	to					1111:1112	to	1111:1112	to	1111:1112	The composite can be used up to five cycles with a small reduction in the removal.					
35622280	1	24	theme	beta-cyclodextrin	231:247	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	24	theme	beta-cyclodextrin	231:247	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	10	25	from	wastewater	1493:1502	arg1	pollutants					1477:1486	phenolic pollutants	1468:1486	phenolic pollutants from wastewater	1468:1502	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	10	26	theme	high	1362:1365	arg1	capacity					1378:1385	high adsorption capacity	1362:1385	high adsorption capacity	1362:1385	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	1	27	theme	epichlorohydrin	249:263	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	27	theme	epichlorohydrin	249:263	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	0	28	theme	epichlorohydrin	19:33	arg1	β-cyclodextrin					48:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	0	29	theme	wastewater	152:161	arg1	treatment					130:138	treatment	130:138	treatment of phenolic wastewater	130:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	0	30	link	cross-linked	35:46	arg1	β-cyclodextrin					48:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	2	31	theme	pollutants	369:378	arg1	study					351:355	Batch study	345:355	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol)	345:427	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	4	32	theme	isotherm	685:692	arg1	model					694:698	the Langmuir isotherm model	672:698	the Langmuir isotherm model	672:698	The isotherm data were more suitably fitted by the Langmuir isotherm model.					
35622280	0	33	theme	novel	13:17	arg1	β-cyclodextrin					48:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	0	34	theme	phenolic	143:150	arg1	wastewater					152:161	phenolic wastewater	143:161	phenolic wastewater	143:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	2	35	theme	phenolic	360:367	arg1	pollutants					369:378	phenolic pollutants	360:378	phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol)	360:427	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	35	theme	phenolic	360:367	arg1	2-chlorophenol					401:414	2-chlorophenol	401:414	2-chlorophenol	401:414	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	35	theme	phenolic	360:367	arg1	phenol					421:426	phenol	421:426	phenol	421:426	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	35	theme	phenolic	360:367	arg1	2,4-dichlorophenol					381:398	2,4-dichlorophenol	381:398	2,4-dichlorophenol	381:398	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	4	36	theme	Langmuir	676:683	arg1	model					694:698	the Langmuir isotherm model	672:698	the Langmuir isotherm model	672:698	The isotherm data were more suitably fitted by the Langmuir isotherm model.					
35622280	0	37	theme	β-cyclodextrin	48:61	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin	0:61	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	8	38	theme	small	1133:1137	arg1	reduction					1139:1147	a small reduction	1131:1147	a small reduction in the removal	1131:1162	The composite can be used up to five cycles with a small reduction in the removal.					
35622280	10	39	theme	rapid	1341:1345	arg1	adsorption					1347:1356	the remarkably rapid adsorption	1326:1356	the remarkably rapid adsorption	1326:1356	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	0	40	theme	cross-linked	35:46	arg1	β-cyclodextrin					48:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	novel epichlorohydrin cross-linked β-cyclodextrin	13:61	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	6	41	theme	pseudo-second-order	899:917	arg1	model					919:923	the pseudo-second-order model	895:923	the pseudo-second-order model	895:923	The kinetic data for all the phenolic pollutants follow the pseudo-second-order model, and the rate was controlled by film diffusion.					
35622280	2	42	theme	aqueous	498:504	arg1	solution					506:513	an aqueous solution	495:513	an aqueous solution	495:513	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	3	43	theme	optimized	520:528	arg1	parameters					530:539	The optimized parameters	516:539	The optimized parameters	516:539	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	3	43	theme	optimized	520:528	arg1	25 °C					558:562	temperature 25 °C	546:562	temperature 25 °C	546:562	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	9	44	theme	Adsorption	1165:1174	arg1	performance					1176:1186	Adsorption performance	1165:1186	Adsorption performance of the synthesized composite for synthetic industrial effluents	1165:1250	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	2	45	dep	pollutants	369:378	arg1	pollutants					369:378	phenolic pollutants	360:378	phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol)	360:427	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	45	dep	pollutants	369:378	arg1	2-chlorophenol					401:414	2-chlorophenol	401:414	2-chlorophenol	401:414	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	45	dep	pollutants	369:378	arg1	phenol					421:426	phenol	421:426	phenol	421:426	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	45	dep	pollutants	369:378	arg1	2,4-dichlorophenol					381:398	2,4-dichlorophenol	381:398	2,4-dichlorophenol	381:398	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	5	46	from	25 ± 1 °C	828:836	arg1	uptake					713:718	The maximum uptake	701:718	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol	701:769	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol was 702.853, 659.475, and 674.155 mg/g, respectively, at 25 ± 1 °C.					
35622280	5	46	from	25 ± 1 °C	828:836	arg1	702.853					775:781	702.853	775:781	702.853	775:781	The maximum uptake for 2,4-dichlorophenol, phenol, and 2-chlorophenol was 702.853, 659.475, and 674.155 mg/g, respectively, at 25 ± 1 °C.					
35622280	9	47	theme	60 min	1293:1298	arg1	time					1311:1314	60 min adsorption time	1293:1314	60 min adsorption time	1293:1314	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	3	48	theme	adsorption	565:574	arg1	60 min					581:586	adsorption time 60 min	565:586	adsorption time 60 min	565:586	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	7	49	theme	Thermodynamic	973:985	arg1	data					987:990	Thermodynamic data	973:990	Thermodynamic data	973:990	Thermodynamic data revealed that the process of removing phenolic pollutants is spontaneous and endothermic.					
35622280	9	50	theme	adsorption	1300:1309	arg1	time					1311:1314	60 min adsorption time	1293:1314	60 min adsorption time	1293:1314	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	10	51	theme	adsorption	1367:1376	arg1	capacity					1378:1385	high adsorption capacity	1362:1385	high adsorption capacity	1362:1385	Based on the remarkably rapid adsorption and high adsorption capacity, the synthesized composite can be considered an efficient adsorbent for treating phenolic pollutants from wastewater.					
35622280	3	52	theme	temperature	546:556	arg1	parameters					530:539	The optimized parameters	516:539	The optimized parameters	516:539	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	3	52	theme	temperature	546:556	arg1	25 °C					558:562	temperature 25 °C	546:562	temperature 25 °C	546:562	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	3	53	theme	dosage	608:613	arg1	0.25 g/L					615:622	dosage 0.25 g/L	608:622	dosage 0.25 g/L	608:622	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	6	54	theme	phenolic	868:875	arg1	pollutants					877:886	all the phenolic pollutants	860:886	all the phenolic pollutants	860:886	The kinetic data for all the phenolic pollutants follow the pseudo-second-order model, and the rate was controlled by film diffusion.					
35622280	3	55	theme	solution	589:596	arg1	pH					598:599	solution pH 7	589:601	solution pH 7	589:601	The optimized parameters were temperature 25 °C, adsorption time 60 min, solution pH 7, and dosage 0.25 g/L.					
35622280	0	56	theme	graphene	91:98	arg1	composite					106:114	reduced graphene oxide composite	83:114	reduced graphene oxide composite adsorbent for treatment of phenolic wastewater	83:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	9	57	theme	synthesized	1195:1205	arg1	composite					1207:1215	the synthesized composite	1191:1215	the synthesized composite	1191:1215	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	1	58	theme	novel	166:170	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	58	theme	novel	166:170	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	2	59	theme	synthesized	452:462	arg1	composite					464:472	the synthesized composite	448:472	the synthesized composite	448:472	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	2	59	theme	synthesized	452:462	arg1	adsorbent					480:488	adsorbent	480:488	adsorbent	480:488	Batch study of phenolic pollutants (2,4-dichlorophenol, 2-chlorophenol, and phenol) was analyzed using the synthesized composite as an adsorbent from an aqueous solution.					
35622280	9	60	dep	%	1271:1271	arg1	78					1269:1270	78	1269:1270	78	1269:1270	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	0	61	theme	reduced	83:89	arg1	composite					106:114	reduced graphene oxide composite	83:114	reduced graphene oxide composite adsorbent for treatment of phenolic wastewater	83:161	Synthesis of novel epichlorohydrin cross-linked β-cyclodextrin functionalized with reduced graphene oxide composite adsorbent for treatment of phenolic wastewater.					
35622280	9	62	theme	composite	1207:1215	arg1	performance					1176:1186	Adsorption performance	1165:1186	Adsorption performance of the synthesized composite for synthetic industrial effluents	1165:1250	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
35622280	1	63	theme	composite	172:180	arg1	RGO-βCD-ECH					274:284	RGO-βCD-ECH	274:284	RGO-βCD-ECH	274:284	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	1	63	theme	composite	172:180	arg1	polymer					265:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer	164:271	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH)	164:285	A novel composite consisting reduced graphene oxide-functionalized beta-cyclodextrin epichlorohydrin polymer (RGO-βCD-ECH) was synthesized for the treatment of phenolic wastewater.					
35622280	9	64	dep	removal	1273:1279	arg1	%					1271:1271	%	1271:1271	%	1271:1271	Adsorption performance of the synthesized composite for synthetic industrial effluents shows that up to 78% removal occurred in 60 min adsorption time.					
36724850	0	0	theme	different	95:103	arg1	dyes					114:117	different cationic dyes	95:117	different cationic dyes	95:117	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	9	1	theme	adsorption	1072:1081	arg1	%					1160:1160	0.009 and 0.156 wt%	1142:1160	0.009 and 0.156 wt%	1142:1160	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	9	1	theme	adsorption	1072:1081	arg1	efficiency					1083:1092	The maximum adsorption efficiency	1060:1092	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye	1060:1136	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	3	2	theme	functional	481:490	arg1	groups					492:497	polar functional groups	475:497	polar functional groups	475:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	2	3	from	abundant	304:311	arg1	nature					316:321	nature	316:321	nature	316:321	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	4	4	theme	native	560:565	arg1	NCNCs					591:595	NCNCs	591:595	NCNCs	591:595	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	4	4	theme	native	560:565	arg1	nanocrystals					577:588	native cellulose nanocrystals	560:588	native cellulose nanocrystals (NCNCs)	560:596	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	5	5	theme	dye	725:727	arg1	performance					737:747	dye removal performance	725:747	dye removal performance	725:747	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	7	6	theme	cellulose	869:877	arg1	MCNCs					893:897	MCNCs	893:897	MCNCs	893:897	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	7	6	theme	cellulose	869:877	arg1	nanocrystals					879:890	modified cellulose nanocrystals	860:890	modified cellulose nanocrystals (MCNCs)	860:898	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	2	7	theme	various	349:355	arg1	rice					384:387	rice	384:387	rice	384:387	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	7	theme	various	349:355	arg1	sources					357:363	various sources	349:363	various sources	349:363	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	7	theme	various	349:355	arg1	cotton					376:381	cotton	376:381	cotton	376:381	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	7	theme	various	349:355	arg1	wheat					390:394	wheat	390:394	wheat	390:394	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	7	theme	various	349:355	arg1	plants					401:406	plants	401:406	plants	401:406	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	12	8	from	groundwork	1429:1438	arg1	sector					1515:1520	the industrial sector	1500:1520	the industrial sector	1500:1520	This research lays the groundwork for environmentally friendly fabrication and consumption in the industrial sector.					
36724850	7	9	theme	nanocrystals	879:890	arg1	ability					849:855	The ability	845:855	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye	845:958	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	2	10	from	nature	316:321	arg1	abundant					304:311	abundant	304:311	abundant	304:311	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	4	11	theme	nanocrystals	577:588	arg1	surface					549:555	the surface	545:555	the surface of native cellulose nanocrystals (NCNCs)	545:596	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	0	12	theme	cationic	105:112	arg1	dyes					114:117	different cationic dyes	95:117	different cationic dyes	95:117	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	5	13	theme	long	684:687	arg1	time					689:692	a long time	682:692	a long time	682:692	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	9	14	theme	NCNCs	1097:1101	arg1	%					1160:1160	0.009 and 0.156 wt%	1142:1160	0.009 and 0.156 wt%	1142:1160	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	9	14	theme	NCNCs	1097:1101	arg1	efficiency					1083:1092	The maximum adsorption efficiency	1060:1092	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye	1060:1136	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	4	15	theme	cellulose	567:575	arg1	NCNCs					591:595	NCNCs	591:595	NCNCs	591:595	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	4	15	theme	cellulose	567:575	arg1	nanocrystals					577:588	native cellulose nanocrystals	560:588	native cellulose nanocrystals (NCNCs)	560:596	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	5	16	used	used	638:641	arg2	anhydride					608:616	Succinic anhydride	599:616	Succinic anhydride	599:616	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	5	17	theme	Succinic	599:606	arg1	anhydride					608:616	Succinic anhydride	599:616	Succinic anhydride	599:616	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	7	18	theme	modified	860:867	arg1	MCNCs					893:897	MCNCs	893:897	MCNCs	893:897	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	7	18	theme	modified	860:867	arg1	nanocrystals					879:890	modified cellulose nanocrystals	860:890	modified cellulose nanocrystals (MCNCs)	860:898	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	10	19	theme	adhesive	1185:1192	arg1	properties					1194:1203	adhesive properties	1185:1203	adhesive properties	1185:1203	The investigation for adhesive properties is based on the strength and toughness of MCNCs.					
36724850	9	20	theme	MCNCs	1107:1111	arg1	%					1160:1160	0.009 and 0.156 wt%	1142:1160	0.009 and 0.156 wt%	1142:1160	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	9	20	theme	MCNCs	1107:1111	arg1	efficiency					1083:1092	The maximum adsorption efficiency	1060:1092	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye	1060:1136	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	10	21	theme	MCNCs	1247:1251	arg1	toughness					1234:1242	toughness	1234:1242	toughness	1234:1242	The investigation for adhesive properties is based on the strength and toughness of MCNCs.					
36724850	10	21	theme	MCNCs	1247:1251	arg1	strength					1221:1228	strength	1221:1228	strength	1221:1228	The investigation for adhesive properties is based on the strength and toughness of MCNCs.					
36724850	3	22	theme	renewable	418:426	arg1	materials					436:444	renewable biomass materials	418:444	renewable biomass materials with a high concentration of polar functional groups	418:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	3	22	theme	renewable	418:426	arg1	CNCs					409:412	CNCs	409:412	CNCs	409:412	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	8	23	theme	cationic	1045:1052	arg1	dyes					1054:1057	the two different cationic dyes	1027:1057	the two different cationic dyes	1027:1057	The MCNCs exhibited high adsorption affinity for the two different cationic dyes.					
36724850	8	24	theme	different	1035:1043	arg1	dyes					1054:1057	the two different cationic dyes	1027:1057	the two different cationic dyes	1027:1057	The MCNCs exhibited high adsorption affinity for the two different cationic dyes.					
36724850	7	25	theme	blue	951:954	arg1	dye					956:958	cationic golden yellow dye and methylene blue dye	910:958	dye	956:958	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	8	26	theme	adsorption	1003:1012	arg1	affinity					1014:1021	high adsorption affinity	998:1021	high adsorption affinity for the two different cationic dyes	998:1057	The MCNCs exhibited high adsorption affinity for the two different cationic dyes.					
36724850	4	27	used	used	511:514	arg2	study					505:509	This study	500:509	This study	500:509	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	12	28	theme	industrial	1504:1513	arg1	sector					1515:1520	the industrial sector	1500:1520	the industrial sector	1500:1520	This research lays the groundwork for environmentally friendly fabrication and consumption in the industrial sector.					
36724850	9	29	theme	cationic	1125:1132	arg1	dye					1134:1136	the cationic dye	1121:1136	the cationic dye	1121:1136	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	6	30	dep	morphology	754:763	arg1	The					750:752	The	750:752	The	750:752	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	3	31	with	materials	436:444	arg1	concentration					458:470	a high concentration	451:470	a high concentration of polar functional groups	451:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	3	32	theme	groups	492:497	arg1	concentration					458:470	a high concentration	451:470	a high concentration of polar functional groups	451:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	11	33	theme	E-51	1339:1342	arg1	system					1350:1355	E-51 epoxy system	1339:1355	E-51 epoxy system	1339:1355	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	1	34	theme	clean	212:216	arg1	environment					228:238	a clean and green environment	210:238	a clean and green environment	210:238	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	5	35	theme	removal	729:735	arg1	performance					737:747	dye removal performance	725:747	dye removal performance	725:747	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	3	36	theme	polar	475:479	arg1	groups					492:497	polar functional groups	475:497	polar functional groups	475:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	8	37	theme	high	998:1001	arg1	affinity					1014:1021	high adsorption affinity	998:1021	high adsorption affinity for the two different cationic dyes	998:1057	The MCNCs exhibited high adsorption affinity for the two different cationic dyes.					
36724850	6	38	theme	&	814:814	arg1	FTIR					804:807	FTIR	804:807	FTIR	804:807	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	6	38	theme	&	814:814	arg1	DTG					816:818	TGA & DTG	810:818	TGA & DTG	810:818	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	11	39	theme	epoxy	1344:1348	arg1	system					1350:1355	E-51 epoxy system	1339:1355	E-51 epoxy system	1339:1355	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	3	40	theme	biomass	428:434	arg1	materials					436:444	renewable biomass materials	418:444	renewable biomass materials with a high concentration of polar functional groups	418:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	3	40	theme	biomass	428:434	arg1	CNCs					409:412	CNCs	409:412	CNCs	409:412	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	11	41	theme	tensile	1282:1288	arg1	strength					1290:1297	tensile strength	1282:1297	tensile strength (2350 MPa)	1282:1308	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	11	41	theme	tensile	1282:1288	arg1	2350 MPa					1300:1307	2350 MPa	1300:1307	2350 MPa	1300:1307	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	6	42	theme	TGA	810:812	arg1	FTIR					804:807	FTIR	804:807	FTIR	804:807	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	6	42	theme	TGA	810:812	arg1	DTG					816:818	TGA & DTG	810:818	TGA & DTG	810:818	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	7	43	theme	golden	919:924	arg1	dye					933:935	cationic golden yellow dye and methylene blue dye	910:958	dye	933:935	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	1	44	theme	green	222:226	arg1	environment					228:238	a clean and green environment	210:238	a clean and green environment	210:238	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	0	45	theme	modified	55:62	arg1	nanocrystals					74:85	modified cellulose nanocrystals	55:85	modified cellulose nanocrystals	55:85	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	12	46	theme	friendly	1460:1467	arg1	fabrication					1469:1479	environmentally friendly fabrication	1444:1479	environmentally friendly fabrication	1444:1479	This research lays the groundwork for environmentally friendly fabrication and consumption in the industrial sector.					
36724850	7	47	theme	methylene	941:949	arg1	dye					956:958	cationic golden yellow dye and methylene blue dye	910:958	dye	956:958	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	7	48	theme	yellow	926:931	arg1	dye					933:935	cationic golden yellow dye and methylene blue dye	910:958	dye	933:935	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	11	49	theme	3 wt	1388:1391	arg1	composites					1394:1403	3 wt% composites	1388:1403	3 wt% composites	1388:1403	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	5	50	theme	sealant	660:666	arg1	chemicals					668:676	sealant chemicals	660:676	sealant chemicals	660:676	Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance.					
36724850	1	51	theme	efficient	130:138	arg1	removal					140:146	efficient removal	130:146	efficient removal of polluted materials	130:168	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	4	52	theme	succinic	516:523	arg1	anhydride					525:533	succinic anhydride	516:533	succinic anhydride	516:533	This study used succinic anhydride to modify the surface of native cellulose nanocrystals (NCNCs).					
36724850	7	53	theme	cationic	910:917	arg1	dye					933:935	cationic golden yellow dye and methylene blue dye	910:958	dye	933:935	The ability of modified cellulose nanocrystals (MCNCs) to adsorb cationic golden yellow dye and methylene blue dye was investigated.					
36724850	3	54	theme	high	453:456	arg1	concentration					458:470	a high concentration	451:470	a high concentration of polar functional groups	451:497	CNCs are renewable biomass materials with a high concentration of polar functional groups.					
36724850	1	55	theme	environment	228:238	arg1	sustainability					192:205	the sustainability	188:205	the sustainability of a clean and green environment	188:238	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	11	56	dep	demonstrated	1260:1271	arg1	improved					1273:1280	improved	1273:1280	demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites	1260:1403	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	10	57	dep	strength	1221:1228	arg1	the					1217:1219	the	1217:1219	the	1217:1219	The investigation for adhesive properties is based on the strength and toughness of MCNCs.					
36724850	0	58	theme	nanocrystals	74:85	arg1	characterization					11:26	characterization	11:26	characterization	11:26	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	0	58	theme	nanocrystals	74:85	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	0	58	theme	nanocrystals	74:85	arg1	adsorption					32:41	adsorption	32:41	adsorption	32:41	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	6	59	theme	CNCs	785:788	arg1	modification					769:780	modification	769:780	modification	769:780	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	6	59	theme	CNCs	785:788	arg1	morphology					754:763	morphology	754:763	morphology	754:763	The morphology and modification of CNCs studied using FTIR, TGA & DTG, XRD, SEM, AFM, and TEM.					
36724850	2	60	theme	cellulose	269:277	arg1	Nanomaterials					241:253	Nanomaterials	241:253	Nanomaterials	241:253	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	60	theme	cellulose	269:277	arg1	CNCs					293:296	CNCs	293:296	CNCs	293:296	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	2	60	theme	cellulose	269:277	arg1	nanocrystals					279:290	cellulose nanocrystals	269:290	particularly cellulose nanocrystals (CNCs)	256:297	Nanomaterials, particularly cellulose nanocrystals (CNCs), are abundant in nature and can be extracted from various sources, including cotton, rice, wheat, and plants.					
36724850	1	61	theme	polluted	151:158	arg1	materials					160:168	polluted materials	151:168	polluted materials	151:168	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	11	62	theme	curing	1363:1368	arg1	agent					1370:1374	a curing agent	1361:1374	a curing agent	1361:1374	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36724850	12	63	theme	environmentally	1444:1458	arg1	fabrication					1469:1479	environmentally friendly fabrication	1444:1479	environmentally friendly fabrication	1444:1479	This research lays the groundwork for environmentally friendly fabrication and consumption in the industrial sector.					
36724850	0	64	theme	cellulose	64:72	arg1	nanocrystals					74:85	modified cellulose nanocrystals	55:85	modified cellulose nanocrystals	55:85	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	0	65	dep	Synthesis	0:8	arg1	behavior					43:50	behavior	43:50	behavior	43:50	Synthesis, characterization and adsorption behavior of modified cellulose nanocrystals towards different cationic dyes.					
36724850	9	66	theme	maximum	1064:1070	arg1	%					1160:1160	0.009 and 0.156 wt%	1142:1160	0.009 and 0.156 wt%	1142:1160	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	9	66	theme	maximum	1064:1070	arg1	efficiency					1083:1092	The maximum adsorption efficiency	1060:1092	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye	1060:1136	The maximum adsorption efficiency of NCNCs and MCNCs towards the cationic dye was 0.009 and 0.156 wt%.					
36724850	1	67	theme	materials	160:168	arg1	removal					140:146	efficient removal	130:146	efficient removal of polluted materials	130:168	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	1	67	theme	materials	160:168	arg1	Green					120:124	Green	120:124	Green	120:124	Green and efficient removal of polluted materials are essential for the sustainability of a clean and green environment.					
36724850	11	68	theme	%	1392:1392	arg1	composites					1394:1403	3 wt% composites	1388:1403	3 wt% composites	1388:1403	MCNCs demonstrated improved tensile strength (2350 MPa) and modulus (13.9 MPa) using E-51 epoxy system and a curing agent compared to 3 wt% composites.					
36508768	3	0	with	presence	620:627	arg1	plenty					680:685	plenty	680:685	plenty of OH-functional groups	680:709	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	3	0	with	presence	620:627	arg1	area					671:674	large surface area	657:674	large surface area	657:674	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	7	1	theme	-12.3	1123:1127	arg1	%					1122:1122	%	1122:1122	%	1122:1122	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	1	2	theme	polylactic	145:154	arg1	PLA					162:164	PLA	162:164	PLA	162:164	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	2	theme	polylactic	145:154	arg1	acid					156:159	polylactic acid	145:159	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	3	theme	electrospun	226:236	arg1	nanofibers					238:247	Cellulose electrospun nanofibers	216:247	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	2	4	theme	Fourier	450:456	arg1	evaluation					406:415	the evaluation	402:415	the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction	402:547	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	1	5	theme	thin-film	306:314	arg1	TFME					334:337	TFME	334:337	TFME	334:337	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	5	theme	thin-film	306:314	arg1	micro-extraction					316:331	thin-film micro-extraction	306:331	thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis	306:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	9	6	theme	analytes	1562:1569	arg1	extraction					1537:1546	the extraction	1533:1546	the extraction of the target analytes in various samples	1533:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	1	7	theme	acid	156:159	arg1	sorbent					294:300	a novel sorbent	286:300	a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis	286:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	7	theme	acid	156:159	arg1	composite					132:140	the composite	128:140	the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	128:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	7	theme	acid	156:159	arg1	acid					156:159	polylactic acid	145:159	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	7	8	theme	5.2	1119:1121	arg1	%					1122:1122	%	1122:1122	%	1122:1122	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	2	9	from	evaluation	406:415	arg1	approved					606:613	approved	606:613	approved	606:613	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	9	from	evaluation	406:415	arg1	fabrication					565:575	the successful fabrication	550:575	the successful fabrication of composite nanaofibers	550:600	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	10	theme	nanaofibers	590:600	arg1	approved					606:613	approved	606:613	approved	606:613	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	10	theme	nanaofibers	590:600	arg1	fabrication					565:575	the successful fabrication	550:575	the successful fabrication of composite nanaofibers	550:600	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	7	11	theme	fiber	1054:1058	arg1	deviations					1078:1087	fiber relative standard deviations	1054:1087	fiber relative standard deviations	1054:1087	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	4	12	theme	main	781:784	arg1	parameters					786:795	various main parameters	773:795	various main parameters	773:795	The effect of various main parameters on extraction efficiency was evaluated.					
36508768	0	13	theme	pesticides	90:99	arg1	extraction					76:85	extraction	76:85	extraction of pesticides from food samples	76:117	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	3	14	theme	extraction	736:745	arg1	efficiency					747:756	PLA extraction efficiency	732:756	PLA extraction efficiency	732:756	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	2	15	theme	composite	580:588	arg1	nanaofibers					590:600	composite nanaofibers	580:600	composite nanaofibers	580:600	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	4	16	theme	various	773:779	arg1	parameters					786:795	various main parameters	773:795	various main parameters	773:795	The effect of various main parameters on extraction efficiency was evaluated.					
36508768	9	17	from	samples	1582:1588	arg1	extraction					1537:1546	the extraction	1533:1546	the extraction of the target analytes in various samples	1533:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	2	18	theme	dispersive	497:506	arg1	spectroscopy					514:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	5	19	dep	ng	897:898	arg1	1.5					893:895	1.5	893:895	1.5	893:895	The LODs (based on S/N = 3) were in the range of 1.0 to 1.5 ng mL-1.					
36508768	8	20	theme	ng	1232:1233	arg1	mL-1					1235:1238	3.0-1900.0 ng mL-1	1221:1238	3.0-1900.0 ng mL-1 for metribuzin and ethofumasate	1221:1270	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	0	21	theme	food	106:109	arg1	samples					111:117	food samples	106:117	food samples	106:117	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	9	22	theme	target	1555:1560	arg1	analytes					1562:1569	the target analytes	1551:1569	the target analytes in various samples	1551:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	6	23	dep	%	997:997	arg1	%					1011:1011	-6.4%	1007:1011	-6.4%	1007:1011	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	4	24	theme	parameters	786:795	arg1	effect					763:768	The effect	759:768	The effect of various main parameters on extraction efficiency	759:820	The effect of various main parameters on extraction efficiency was evaluated.					
36508768	9	25	theme	developed	1339:1347	arg1	method					1349:1354	The developed method	1335:1354	The developed method	1335:1354	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	3	26	theme	PLA	732:734	arg1	efficiency					747:756	PLA extraction efficiency	732:756	PLA extraction efficiency	732:756	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	7	27	theme	%	1128:1128	arg1	range					1110:1114	the range	1106:1114	the range of 5.2%-12.3%	1106:1128	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	4	28	from	effect	763:768	arg1	efficiency					811:820	extraction efficiency	800:820	extraction efficiency	800:820	The effect of various main parameters on extraction efficiency was evaluated.					
36508768	3	29	theme	groups	704:709	arg1	plenty					680:685	plenty	680:685	plenty of OH-functional groups	680:709	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	3	29	theme	groups	704:709	arg1	area					671:674	large surface area	657:674	large surface area	657:674	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	3	30	theme	OH-functional	690:702	arg1	groups					704:709	OH-functional groups	690:709	OH-functional groups	690:709	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	9	31	from	analytes	1562:1569	arg1	samples					1582:1588	various samples	1574:1588	various samples	1574:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	9	32	theme	prominent	1504:1512	arg1	PLA/r-MIL-88A/Cellulose					1471:1493	the PLA/r-MIL-88A/Cellulose	1467:1493	the PLA/r-MIL-88A/Cellulose	1467:1493	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	9	32	theme	prominent	1504:1512	arg1	film					1524:1527	a prominent composite film	1502:1527	a prominent composite film for the extraction of the target analytes in various samples	1502:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	7	33	located	observed	1094:1101	arg2	fiber					1045:1049	the fiber	1041:1049	the fiber to fiber relative standard deviations	1041:1087	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	7	33	located	observed	1094:1101	arg1	range					1110:1114	the range	1106:1114	the range of 5.2%-12.3%	1106:1128	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	7	33	located	observed	1094:1101	arg1	addition					1031:1038	addition	1031:1038	addition	1031:1038	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	1	34	dep	acid	156:159	arg1	nanofibers					238:247	Cellulose electrospun nanofibers	216:247	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	34	dep	acid	156:159	arg1	r-MIL-88A					204:212	r-MIL-88A	204:212	r-MIL-88A	204:212	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	34	dep	acid	156:159	arg1	framework					193:201	Iron-based metal-organic framework	168:201	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	3	35	theme	surface	663:669	arg1	area					671:674	large surface area	657:674	large surface area	657:674	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	0	36	theme	composite	27:35	arg1	Application					0:10	Application	0:10	Application of electrospun composite	0:35	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	9	37	theme	various	1574:1580	arg1	samples					1582:1588	various samples	1574:1588	various samples	1574:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	9	38	from	extraction	1537:1546	arg1	samples					1582:1588	various samples	1574:1588	various samples	1574:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	1	39	theme	Iron-based	168:177	arg1	r-MIL-88A					204:212	r-MIL-88A	204:212	r-MIL-88A	204:212	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	39	theme	Iron-based	168:177	arg1	framework					193:201	Iron-based metal-organic framework	168:201	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	0	40	theme	electrospun	15:25	arg1	composite					27:35	electrospun composite	15:35	electrospun composite	15:35	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	9	41	theme	fruit	1376:1380	arg1	juice					1382:1386	fruit juice	1376:1386	fruit juice	1376:1386	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	2	42	theme	diffraction	537:547	arg1	evaluation					406:415	the evaluation	402:415	the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction	402:547	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	3	43	theme	large	657:661	arg1	area					671:674	large surface area	657:674	large surface area	657:674	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	8	44	theme	3.0-1900.0	1221:1230	arg1	ng					1232:1233	ng	1232:1233	ng	1232:1233	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	1	45	theme	metal-organic	179:191	arg1	r-MIL-88A					204:212	r-MIL-88A	204:212	r-MIL-88A	204:212	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	45	theme	metal-organic	179:191	arg1	framework					193:201	Iron-based metal-organic framework	168:201	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	7	46	theme	standard	1069:1076	arg1	deviations					1078:1087	fiber relative standard deviations	1054:1087	fiber relative standard deviations	1054:1087	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	5	47	theme	mL-1	900:903	arg1	range					877:881	the range	873:881	the range of 1.0 to 1.5 ng mL-1	873:903	The LODs (based on S/N = 3) were in the range of 1.0 to 1.5 ng mL-1.					
36508768	2	48	theme	X-ray	531:535	arg1	diffraction					537:547	X-ray diffraction	531:547	X-ray diffraction	531:547	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	1	49	theme	selected	348:355	arg1	pesticides					357:366	four selected pesticides	343:366	four selected pesticides followed by GC-FID analysis	343:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	8	50	theme	optimized	1144:1152	arg1	factors					1154:1160	the optimized factors	1140:1160	the optimized factors	1140:1160	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	6	51	theme	%	997:997	arg1	range					978:982	the range	974:982	the range of 4.8% - 5.6% and 5.2%-6.4%, respectively	974:1025	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	2	52	theme	microscopy	438:447	arg1	evaluation					406:415	the evaluation	402:415	the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction	402:547	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	6	53	theme	standard	939:946	arg1	RSDs					960:963	RSDs	960:963	RSDs	960:963	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	6	53	theme	standard	939:946	arg1	deviations					948:957	relative standard deviations	930:957	Intra-day and inter-day relative standard deviations (RSDs)	906:964	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	1	54	theme	pesticides	357:366	arg1	TFME					334:337	TFME	334:337	TFME	334:337	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	54	theme	pesticides	357:366	arg1	micro-extraction					316:331	thin-film micro-extraction	306:331	thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis	306:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	2	55	theme	energy	490:495	arg1	spectroscopy					514:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	56	theme	electron	429:436	arg1	microscopy					438:447	scanning electron microscopy	420:447	scanning electron microscopy	420:447	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	6	57	theme	relative	930:937	arg1	RSDs					960:963	RSDs	960:963	RSDs	960:963	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	6	57	theme	relative	930:937	arg1	deviations					948:957	relative standard deviations	930:957	Intra-day and inter-day relative standard deviations (RSDs)	906:964	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	2	58	dep	transform	458:466	arg1	infrared					468:475	infrared	468:475	transform infrared spectroscopy energy dispersive X-ray spectroscopy	458:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	59	theme	X-ray	508:512	arg1	spectroscopy					514:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	5	60	dep	1.5	893:895	arg1	to					890:891	to	890:891	to	890:891	The LODs (based on S/N = 3) were in the range of 1.0 to 1.5 ng mL-1.					
36508768	2	61	theme	scanning	420:427	arg1	microscopy					438:447	scanning electron microscopy	420:447	scanning electron microscopy	420:447	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	6	62	theme	inter-day	920:928	arg1	RSDs					960:963	RSDs	960:963	RSDs	960:963	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	6	62	theme	inter-day	920:928	arg1	deviations					948:957	relative standard deviations	930:957	Intra-day and inter-day relative standard deviations (RSDs)	906:964	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	2	63	dep	Fourier	450:456	arg1	transform					458:466	transform	458:466	transform infrared spectroscopy energy dispersive X-ray spectroscopy	458:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	0	64	from	samples	111:117	arg1	extraction					76:85	extraction	76:85	extraction of pesticides from food samples	76:117	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	3	65	theme	r-MIL-88A/Cellulose	632:650	arg1	presence					620:627	The presence	616:627	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups	616:709	The presence of r-MIL-88A/Cellulose with large surface area and plenty of OH-functional groups results in improving PLA extraction efficiency.					
36508768	1	66	theme	novel	288:292	arg1	sorbent					294:300	a novel sorbent	286:300	a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis	286:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	66	theme	novel	288:292	arg1	composite					132:140	the composite	128:140	the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	128:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	1	66	theme	novel	288:292	arg1	acid					156:159	polylactic acid	145:159	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	2	67	theme	successful	554:563	arg1	approved					606:613	approved	606:613	approved	606:613	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	2	67	theme	successful	554:563	arg1	fabrication					565:575	the successful fabrication	550:575	the successful fabrication of composite nanaofibers	550:600	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	1	68	theme	GC-FID	380:385	arg1	analysis					387:394	GC-FID analysis	380:394	GC-FID analysis	380:394	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36508768	7	69	theme	relative	1060:1067	arg1	deviations					1078:1087	fiber relative standard deviations	1054:1087	fiber relative standard deviations	1054:1087	In addition, the fiber to fiber relative standard deviations were observed in the range of 5.2%-12.3%.					
36508768	5	70	dep	mL-1	900:903	arg1	ng					897:898	ng	897:898	ng	897:898	The LODs (based on S/N = 3) were in the range of 1.0 to 1.5 ng mL-1.					
36508768	4	71	theme	extraction	800:809	arg1	efficiency					811:820	extraction efficiency	800:820	extraction efficiency	800:820	The effect of various main parameters on extraction efficiency was evaluated.					
36508768	8	72	theme	mL-1	1235:1238	arg1	range					1212:1216	the range	1208:1216	the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate	1208:1270	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	6	73	theme	%	990:990	arg1	range					978:982	the range	974:982	the range of 4.8% - 5.6% and 5.2%-6.4%, respectively	974:1025	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	2	74	theme	spectroscopy	477:488	arg1	spectroscopy					514:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	spectroscopy energy dispersive X-ray spectroscopy	477:525	From the evaluation of scanning electron microscopy, Fourier transform infrared spectroscopy energy dispersive X-ray spectroscopy and X-ray diffraction, the successful fabrication of composite nanaofibers was approved.					
36508768	8	75	theme	linearity	1174:1182	arg1	ranges					1184:1189	acceptable linearity ranges	1163:1189	acceptable linearity ranges	1163:1189	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	9	76	theme	composite	1514:1522	arg1	PLA/r-MIL-88A/Cellulose					1471:1493	the PLA/r-MIL-88A/Cellulose	1467:1493	the PLA/r-MIL-88A/Cellulose	1467:1493	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	9	76	theme	composite	1514:1522	arg1	film					1524:1527	a prominent composite film	1502:1527	a prominent composite film for the extraction of the target analytes in various samples	1502:1588	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	8	77	theme	acceptable	1163:1172	arg1	ranges					1184:1189	acceptable linearity ranges	1163:1189	acceptable linearity ranges	1163:1189	By using the optimized factors, acceptable linearity ranges were obtained in the range of 3.0-1900.0 ng mL-1 for metribuzin and ethofumasate, and 5.0-2000.0 for atrazine and ametryn (R2 = 0.9913-0.9967).					
36508768	0	78	theme	efficient	54:62	arg1	sorbent					64:70	an efficient sorbent	51:70	an efficient sorbent for extraction of pesticides from food samples	51:117	Application of electrospun composite nanofibers as an efficient sorbent for extraction of pesticides from food samples.					
36508768	6	79	theme	Intra-day	906:914	arg1	RSDs					960:963	RSDs	960:963	RSDs	960:963	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	6	79	theme	Intra-day	906:914	arg1	deviations					948:957	relative standard deviations	930:957	Intra-day and inter-day relative standard deviations (RSDs)	906:964	Intra-day and inter-day relative standard deviations (RSDs) were in the range of 4.8% - 5.6% and 5.2%-6.4%, respectively.					
36508768	9	80	theme	honey	1410:1414	arg1	samples					1416:1422	honey samples	1410:1422	honey samples	1410:1422	The developed method was investigated in fruit juice, vegetables, milk and honey samples, and recoveries (79.3-95.6%) indicate that the PLA/r-MIL-88A/Cellulose can be a prominent composite film for the extraction of the target analytes in various samples.					
36508768	1	81	theme	Cellulose	216:224	arg1	nanofibers					238:247	Cellulose electrospun nanofibers	216:247	polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers	145:247	Herein, the composite of polylactic acid (PLA)/ Iron-based metal-organic framework (r-MIL-88A)/ Cellulose electrospun nanofibers was fabricated; and then, applied as a novel sorbent for thin-film micro-extraction (TFME) of four selected pesticides followed by GC-FID analysis.					
36720331	7	0	theme	Composite	1109:1117	arg1	membranes					1127:1135	Composite fibrous membranes	1109:1135	Composite fibrous membranes containing 2 wt% of ZnO-NPs	1109:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	4	1	theme	study	497:501	arg1	a					520:520	a	520:520	a	520:520	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	1	theme	study	497:501	arg1	three-fold					508:517	three-fold	508:517	three-fold	508:517	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	1	theme	study	497:501	arg1	objectives					478:487	The objectives	474:487	The objectives of this study	474:501	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	8	2	theme	devoid	1452:1457	arg1	membranes					1442:1450	the membranes	1438:1450	the membranes devoid of ZnO-NPs	1438:1468	In addition, composite membranes showed remarkable epithelialization, neovascularization, and anti-inflammatory response than that of the membranes devoid of ZnO-NPs.					
36720331	1	3	theme	promising	155:163	arg1	platform					165:172	a promising platform	153:172	a promising platform for wound healing	153:190	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	9	4	theme	composite	1491:1499	arg1	membranes					1509:1517	these composite fibrous membranes	1485:1517	these composite fibrous membranes	1485:1517	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	0	5	theme	zinc	75:78	arg1	oxide					80:84	zinc oxide	75:84	zinc oxide	75:84	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	5	6	theme	oxidation	858:866	arg1	degrees					868:874	different oxidation degrees	848:874	different oxidation degrees (Dox (%))	848:884	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	6	7	theme	uniform	993:999	arg1	fibers					1001:1006	smooth and uniform fibers	982:1006	smooth and uniform fibers	982:1006	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	6	8	theme	stable	1071:1076	arg1	membranes					1098:1106	structurally stable and water-insoluble membranes	1058:1106	structurally stable and water-insoluble membranes	1058:1106	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	2	9	used	used	367:370	arg2	alginate					344:351	Sodium alginate	337:351	Sodium alginate (SA)	337:356	Sodium alginate (SA) is being used for different types of applications.					
36720331	2	9	used	used	367:370	arg2	SA					354:355	SA	354:355	SA	354:355	Sodium alginate (SA) is being used for different types of applications.					
36720331	4	10	theme	zinc	668:671	arg1	oxide					673:677	zinc oxide	668:677	zinc oxide nanoparticles (ZnO-NPs)	668:701	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	1	11	theme	antibacterial	266:278	arg1	properties					302:311	antibacterial and anti-inflammatory properties	266:311	antibacterial and anti-inflammatory properties	266:311	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	0	12	theme	wound	111:115	arg1	healing					117:123	wound healing	111:123	wound healing	111:123	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	6	13	theme	smooth	982:987	arg1	fibers					1001:1006	smooth and uniform fibers	982:1006	smooth and uniform fibers	982:1006	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	4	14	theme	antibacterial	723:735	arg1	properties					759:768	antibacterial and anti-inflammatory properties	723:768	antibacterial and anti-inflammatory properties as well as biocompatibility of membranes	723:809	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	2	15	theme	applications	395:406	arg1	types					386:390	different types	376:390	different types of applications	376:406	Sodium alginate (SA) is being used for different types of applications.					
36720331	6	16	dep	OSA	956:958	arg1	Dox					961:963	Dox	961:963	Dox	961:963	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	6	16	dep	OSA	956:958	arg1	%					970:970	~48 %	966:970	~48 %	966:970	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	4	17	theme	membranes	801:809	arg1	properties					759:768	antibacterial and anti-inflammatory properties	723:768	antibacterial and anti-inflammatory properties as well as biocompatibility of membranes	723:809	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	17	theme	membranes	801:809	arg1	biocompatibility					781:796	biocompatibility	781:796	antibacterial and anti-inflammatory properties as well as biocompatibility of membranes	723:809	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	5	18	theme	molar	917:921	arg1	ratio					923:927	the molar ratio	913:927	the molar ratio of sodium periodate to SA	913:953	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	1	19	theme	wound	178:182	arg1	healing					184:190	wound healing	178:190	wound healing	178:190	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	7	20	theme	fibrous	1119:1125	arg1	membranes					1127:1135	Composite fibrous membranes	1109:1135	Composite fibrous membranes containing 2 wt% of ZnO-NPs	1109:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	4	21	theme	fibrous	623:629	arg1	membranes					631:639	composite fibrous membranes	613:639	composite fibrous membranes	613:639	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	2	22	theme	Sodium	337:342	arg1	SA					354:355	SA	354:355	SA	354:355	Sodium alginate (SA) is being used for different types of applications.					
36720331	2	22	theme	Sodium	337:342	arg1	alginate					344:351	Sodium alginate	337:351	Sodium alginate (SA)	337:356	Sodium alginate (SA) is being used for different types of applications.					
36720331	7	23	theme	good	1175:1178	arg1	biocompatibility					1180:1195	good biocompatibility	1175:1195	good biocompatibility	1175:1195	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	3	24	theme	poor	422:425	arg1	spinnability					427:438	the poor spinnability	418:438	the poor spinnability of SA	418:444	However, the poor spinnability of SA restricts its applications.					
36720331	6	25	theme	water-insoluble	1082:1096	arg1	membranes					1098:1106	structurally stable and water-insoluble membranes	1058:1106	structurally stable and water-insoluble membranes	1058:1106	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	4	26	theme	sodium	546:551	arg1	OSA					563:565	OSA	563:565	OSA	563:565	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	26	theme	sodium	546:551	arg1	alginate					553:560	oxidized sodium alginate	537:560	oxidized sodium alginate (OSA)	537:566	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	5	27	dep	degrees	868:874	arg1	Dox					877:879	Dox	877:879	Dox (%)	877:883	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	5	27	dep	degrees	868:874	arg1	%					882:882	%	882:882	%	882:882	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	2	28	theme	different	376:384	arg1	types					386:390	different types	376:390	different types of applications	376:406	Sodium alginate (SA) is being used for different types of applications.					
36720331	0	29	theme	sodium	22:27	arg1	alginate					29:36	oxidized sodium alginate	13:36	oxidized sodium alginate	13:36	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	1	30	theme	anti-inflammatory	284:300	arg1	properties					302:311	antibacterial and anti-inflammatory properties	266:311	antibacterial and anti-inflammatory properties	266:311	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	9	31	theme	fibrous	1501:1507	arg1	membranes					1509:1517	these composite fibrous membranes	1485:1517	these composite fibrous membranes	1485:1517	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	0	32	theme	oxidized	13:20	arg1	alginate					29:36	oxidized sodium alginate	13:36	oxidized sodium alginate	13:36	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	8	33	theme	remarkable	1344:1353	arg1	epithelialization					1355:1371	remarkable epithelialization	1344:1371	remarkable epithelialization	1344:1371	In addition, composite membranes showed remarkable epithelialization, neovascularization, and anti-inflammatory response than that of the membranes devoid of ZnO-NPs.					
36720331	6	34	theme	dihydrazide	1027:1037	arg1	ADH					1040:1042	ADH	1040:1042	ADH	1040:1042	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	6	34	theme	dihydrazide	1027:1037	arg1	%					1015:1015	0.5 wt%	1009:1015	0.5 wt% of adipic dihydrazide (ADH)	1009:1043	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	6	34	theme	dihydrazide	1027:1037	arg1	dihydrazide					1027:1037	adipic dihydrazide	1020:1037	adipic dihydrazide (ADH)	1020:1043	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	7	35	theme	bactericidal	1201:1212	arg1	effect					1214:1219	bactericidal effect	1201:1219	bactericidal effect	1201:1219	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	7	36	dep	coli	1241:1244	arg1	coli					1250:1253	E. coli	1247:1253	E. coli	1247:1253	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	4	37	theme	composite	613:621	arg1	membranes					631:639	composite fibrous membranes	613:639	composite fibrous membranes	613:639	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	0	38	theme	alginate	29:36	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide	0:84	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	1	39	theme	angiogenic	317:326	arg1	ability					328:334	angiogenic ability	317:334	angiogenic ability	317:334	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	4	40	dep	fabricate	603:611	arg1	b					597:597	b	597:597	b	597:597	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	9	41	theme	healing	1557:1563	arg1	applications					1565:1576	wound healing applications	1551:1576	wound healing applications	1551:1576	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	7	42	dep	aureus	1275:1280	arg1	aureus					1286:1291	S. aureus	1283:1291	S. aureus	1283:1291	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	0	43	theme	electrospun	46:56	arg1	bio-hybrids					58:68	its electrospun bio-hybrids	42:68	its electrospun bio-hybrids	42:68	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	4	44	dep	three-fold	508:517	arg1	a					520:520	a	520:520	a	520:520	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	44	dep	three-fold	508:517	arg1	three-fold					508:517	three-fold	508:517	three-fold	508:517	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	44	dep	three-fold	508:517	arg1	objectives					478:487	The objectives	474:487	The objectives of this study	474:501	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	45	theme	oxidized	537:544	arg1	OSA					563:565	OSA	563:565	OSA	563:565	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	45	theme	oxidized	537:544	arg1	alginate					553:560	oxidized sodium alginate	537:560	oxidized sodium alginate (OSA)	537:566	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	9	46	theme	broad	1528:1532	arg1	implications					1534:1545	broad implications	1528:1545	broad implications for wound healing applications	1528:1576	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	6	47	theme	adipic	1020:1025	arg1	ADH					1040:1042	ADH	1040:1042	ADH	1040:1042	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	6	47	theme	adipic	1020:1025	arg1	dihydrazide					1027:1037	adipic dihydrazide	1020:1037	adipic dihydrazide (ADH)	1020:1043	OSA (Dox, ~48 %) afforded smooth and uniform fibers; 0.5 wt% of adipic dihydrazide (ADH) evolved into structurally stable and water-insoluble membranes.					
36720331	8	48	theme	composite	1317:1325	arg1	membranes					1327:1335	composite membranes	1317:1335	composite membranes	1317:1335	In addition, composite membranes showed remarkable epithelialization, neovascularization, and anti-inflammatory response than that of the membranes devoid of ZnO-NPs.					
36720331	4	49	theme	oxide	673:677	arg1	nanoparticles					679:691	zinc oxide nanoparticles	668:691	zinc oxide nanoparticles (ZnO-NPs)	668:701	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	4	49	theme	oxide	673:677	arg1	ZnO-NPs					694:700	ZnO-NPs	694:700	ZnO-NPs	694:700	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	7	50	theme	ZnO-NPs	1157:1163	arg1	ZnO-NPs					1157:1163	ZnO-NPs	1157:1163	ZnO-NPs	1157:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	7	50	theme	ZnO-NPs	1157:1163	arg1	%					1152:1152	2 wt%	1148:1152	2 wt% of ZnO-NPs	1148:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	4	51	theme	anti-inflammatory	741:757	arg1	properties					759:768	antibacterial and anti-inflammatory properties	723:768	antibacterial and anti-inflammatory properties as well as biocompatibility of membranes	723:809	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	0	52	with	Synthesis	0:8	arg1	oxide					80:84	zinc oxide	75:84	zinc oxide	75:84	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	1	53	theme	Electrospun	126:136	arg1	fibers					138:143	Electrospun fibers	126:143	Electrospun fibers	126:143	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	1	54	theme	requisite	212:220	arg1	properties					302:311	antibacterial and anti-inflammatory properties	266:311	antibacterial and anti-inflammatory properties	266:311	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	1	54	theme	requisite	212:220	arg1	ability					328:334	angiogenic ability	317:334	angiogenic ability	317:334	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	1	54	theme	requisite	212:220	arg1	characteristics					222:236	requisite characteristics	212:236	requisite characteristics	212:236	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36720331	9	55	contain	have	1523:1526	arg2	implications					1534:1545	broad implications	1528:1545	broad implications for wound healing applications	1528:1576	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	9	55	contain	have	1523:1526	arg1	membranes					1509:1517	these composite fibrous membranes	1485:1517	these composite fibrous membranes	1485:1517	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	8	56	theme	anti-inflammatory	1398:1414	arg1	response					1416:1423	anti-inflammatory response	1398:1423	anti-inflammatory response	1398:1423	In addition, composite membranes showed remarkable epithelialization, neovascularization, and anti-inflammatory response than that of the membranes devoid of ZnO-NPs.					
36720331	9	57	theme	wound	1551:1555	arg1	applications					1565:1576	wound healing applications	1551:1576	wound healing applications	1551:1576	Conclusively, these composite fibrous membranes may have broad implications for wound healing applications.					
36720331	5	58	theme	different	848:856	arg1	degrees					868:874	different oxidation degrees	848:874	different oxidation degrees (Dox (%))	848:884	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	5	59	theme	sodium	932:937	arg1	periodate					939:947	sodium periodate	932:947	sodium periodate	932:947	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	8	60	theme	ZnO-NPs	1462:1468	arg1	devoid					1452:1457	devoid	1452:1457	devoid	1452:1457	In addition, composite membranes showed remarkable epithelialization, neovascularization, and anti-inflammatory response than that of the membranes devoid of ZnO-NPs.					
36720331	3	61	theme	SA	443:444	arg1	spinnability					427:438	the poor spinnability	418:438	the poor spinnability of SA	418:444	However, the poor spinnability of SA restricts its applications.					
36720331	0	62	theme	bio-hybrids	58:68	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide	0:84	Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.					
36720331	5	63	theme	periodate	939:947	arg1	ratio					923:927	the molar ratio	913:927	the molar ratio of sodium periodate to SA	913:953	OSA displaying different oxidation degrees (Dox (%)) was synthesized by varying the molar ratio of sodium periodate to SA.					
36720331	7	64	contain	containing	1137:1146	arg2	ZnO-NPs					1157:1163	ZnO-NPs	1157:1163	ZnO-NPs	1157:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	7	64	contain	containing	1137:1146	arg1	membranes					1127:1135	Composite fibrous membranes	1109:1135	Composite fibrous membranes containing 2 wt% of ZnO-NPs	1109:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	7	64	contain	containing	1137:1146	arg2	%					1152:1152	2 wt%	1148:1152	2 wt% of ZnO-NPs	1148:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	4	65	dep	decipher	714:721	arg1	c					708:708	c	708:708	c	708:708	The objectives of this study were three-fold: a) to synthesize oxidized sodium alginate (OSA) to improve its spinnability, b) to fabricate composite fibrous membranes by blending OSA along with zinc oxide nanoparticles (ZnO-NPs), and c) to decipher antibacterial and anti-inflammatory properties as well as biocompatibility of membranes in vitro and in vivo.					
36720331	7	66	theme	2 wt	1148:1151	arg1	ZnO-NPs					1157:1163	ZnO-NPs	1157:1163	ZnO-NPs	1157:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	7	66	theme	2 wt	1148:1151	arg1	%					1152:1152	2 wt%	1148:1152	2 wt% of ZnO-NPs	1148:1163	Composite fibrous membranes containing 2 wt% of ZnO-NPs displayed good biocompatibility and bactericidal effect against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in vitro.					
36720331	1	67	theme	wound	242:246	arg1	repair					248:253	wound repair	242:253	wound repair	242:253	Electrospun fibers provide a promising platform for wound healing; however, they lack requisite characteristics for wound repair, including antibacterial and anti-inflammatory properties and angiogenic ability.					
36175379	2	0	theme	lower	486:490	arg1	free-					492:496	lower free-	486:496	lower free-	486:496	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	2	1	theme	glucose	613:619	arg1	content					593:599	the content	589:599	the content of maltose, glucose and maltotriose	589:635	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	3	2	dep	observed	896:903	arg1	%					910:910	2.92%	906:910	2.92%	906:910	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	3	2	dep	observed	896:903	arg1	%					920:920	3.09%	916:920	3.09%	916:920	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	1	3	theme	commercial	140:149	arg1	Malt					158:161	Malt 1	158:163	Malt 1	158:163	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	3	theme	commercial	140:149	arg1	Malt					169:172	Malt 2	169:174	Malt 2	169:174	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	3	theme	commercial	140:149	arg1	malts					151:155	Canadian and French commercial malts	120:155	Canadian and French commercial malts (Malt 1 and Malt 2)	120:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	4	from	effects	70:76	arg1	efficiency					188:197	mashing efficiency	180:197	mashing efficiency	180:197	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	4	from	effects	70:76	arg1	production					204:213	production	204:213	production of violate compounds during fermentation	204:254	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	5	5	theme	malt	1083:1086	arg1	removal					1096:1102	malt protein removal	1083:1102	malt protein removal by Neutrase	1083:1114	This suggests that malt protein removal by Neutrase impairs the production of volatile compounds.					
36175379	2	6	theme	α-amylase	529:537	arg1	activity					546:553	higher α-amylase enzyme activity	522:553	higher α-amylase enzyme activity	522:553	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	0	7	from	Impacts	0:6	arg1	efficiency					54:63	yeast fermentation efficiency	35:63	yeast fermentation efficiency	35:63	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	2	8	theme	maltose	604:610	arg1	content					593:599	the content	589:599	the content of maltose, glucose and maltotriose	589:635	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	1	9	theme	violate	218:224	arg1	compounds					226:234	violate compounds	218:234	violate compounds	218:234	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	2	10	theme	higher	522:527	arg1	activity					546:553	higher α-amylase enzyme activity	522:553	higher α-amylase enzyme activity	522:553	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	3	11	theme	increased	706:714	arg1	ratio					732:736	the increased glucose/maltose ratio	702:736	the increased glucose/maltose ratio after Neutrase addition	702:760	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	1	12	theme	compounds	226:234	arg1	efficiency					188:197	mashing efficiency	180:197	mashing efficiency	180:197	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	12	theme	compounds	226:234	arg1	production					204:213	production	204:213	production of violate compounds during fermentation	204:254	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	13	theme	headspace-solid-phase	325:345	arg1	chromatography					302:315	high performance liquid chromatography	278:315	high performance liquid chromatography (HPLC)	278:322	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	13	theme	headspace-solid-phase	325:345	arg1	microextraction					347:361	headspace-solid-phase microextraction	325:361	headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	325:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	5	14	theme	volatile	1142:1149	arg1	compounds					1151:1159	volatile compounds	1142:1159	volatile compounds	1142:1159	This suggests that malt protein removal by Neutrase impairs the production of volatile compounds.					
36175379	5	15	theme	compounds	1151:1159	arg1	production					1128:1137	the production	1124:1137	the production of volatile compounds	1124:1159	This suggests that malt protein removal by Neutrase impairs the production of volatile compounds.					
36175379	1	16	dep	malts	151:155	arg1	Malt					158:161	Malt 1	158:163	Malt 1	158:163	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	16	dep	malts	151:155	arg1	Malt					169:172	Malt 2	169:174	Malt 2	169:174	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	16	dep	malts	151:155	arg1	malts					151:155	Canadian and French commercial malts	120:155	Canadian and French commercial malts (Malt 1 and Malt 2)	120:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	2	17	theme	maltotriose	625:635	arg1	content					593:599	the content	589:599	the content of maltose, glucose and maltotriose	589:635	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	3	18	theme	glucose/maltose	716:730	arg1	ratio					732:736	the increased glucose/maltose ratio	702:736	the increased glucose/maltose ratio after Neutrase addition	702:760	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	3	19	theme	Neutrase	744:751	arg1	addition					753:760	Neutrase addition	744:760	Neutrase addition	744:760	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	2	20	theme	glucose	663:669	arg1	content					671:677	only glucose content	658:677	only glucose content	658:677	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	1	21	theme	malt	81:84	arg1	removal					94:100	malt protein removal	81:100	malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2)	81:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	0	22	theme	protein	16:22	arg1	removal					24:30	malt protein removal	11:30	malt protein removal	11:30	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	2	23	theme	only	658:661	arg1	content					671:677	only glucose content	658:677	only glucose content	658:677	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	1	24	theme	protein	86:92	arg1	removal					94:100	malt protein removal	81:100	malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2)	81:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	0	25	theme	malt	11:14	arg1	removal					24:30	malt protein removal	11:30	malt protein removal	11:30	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	1	26	theme	removal	94:100	arg1	effects					70:76	The effects	66:76	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation	66:254	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	3	27	theme	significant	867:877	arg1	differences					879:889	no significant differences	864:889	no significant differences	864:889	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	1	28	theme	gas	376:378	arg1	spectrometry					400:411	gas chromatography-mass spectrometry	376:411	gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	376:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	0	29	theme	removal	24:30	arg1	Impacts					0:6	Impacts	0:6	Impacts of malt protein removal on yeast fermentation efficiency	0:63	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	3	30	theme	higher	769:774	arg1	concentration					784:796	higher ethanol concentration	769:796	higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%)	769:841	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	2	31	theme	enzyme	539:544	arg1	activity					546:553	higher α-amylase enzyme activity	522:553	higher α-amylase enzyme activity	522:553	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	1	32	theme	chromatography-mass	380:398	arg1	spectrometry					400:411	gas chromatography-mass spectrometry	376:411	gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	376:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	2	33	theme	HPLC	439:442	arg1	results					444:450	HPLC results	439:450	HPLC results	439:450	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	2	34	contain	containing	475:484	arg1	Malt					468:471	Malt 1	468:473	Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity	468:553	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	2	34	contain	containing	475:484	arg2	total-β-amylase					502:516	total-β-amylase	502:516	total-β-amylase	502:516	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	2	34	contain	containing	475:484	arg2	activity					546:553	higher α-amylase enzyme activity	522:553	higher α-amylase enzyme activity	522:553	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	2	34	contain	containing	475:484	arg2	free-					492:496	lower free-	486:496	lower free-	486:496	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	5	35	theme	protein	1088:1094	arg1	removal					1096:1102	malt protein removal	1083:1102	malt protein removal by Neutrase	1083:1114	This suggests that malt protein removal by Neutrase impairs the production of volatile compounds.					
36175379	0	36	theme	fermentation	41:52	arg1	efficiency					54:63	yeast fermentation efficiency	35:63	yeast fermentation efficiency	35:63	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	1	37	theme	high	278:281	arg1	HPLC					318:321	HPLC	318:321	HPLC	318:321	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	37	theme	high	278:281	arg1	chromatography					302:315	high performance liquid chromatography	278:315	high performance liquid chromatography (HPLC)	278:322	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	37	theme	high	278:281	arg1	microextraction					347:361	headspace-solid-phase microextraction	325:361	headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	325:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	38	theme	spectrometry	400:411	arg1	HS-SMPE-GC-MS					423:435	HS-SMPE-GC-MS	423:435	HS-SMPE-GC-MS	423:435	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	38	theme	spectrometry	400:411	arg1	analysis					413:420	gas chromatography-mass spectrometry analysis	376:420	gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	376:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	0	39	theme	yeast	35:39	arg1	efficiency					54:63	yeast fermentation efficiency	35:63	yeast fermentation efficiency	35:63	Impacts of malt protein removal on yeast fermentation efficiency.					
36175379	1	40	theme	performance	283:293	arg1	HPLC					318:321	HPLC	318:321	HPLC	318:321	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	40	theme	performance	283:293	arg1	chromatography					302:315	high performance liquid chromatography	278:315	high performance liquid chromatography (HPLC)	278:322	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	40	theme	performance	283:293	arg1	microextraction					347:361	headspace-solid-phase microextraction	325:361	headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	325:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	41	theme	liquid	295:300	arg1	HPLC					318:321	HPLC	318:321	HPLC	318:321	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	41	theme	liquid	295:300	arg1	chromatography					302:315	high performance liquid chromatography	278:315	high performance liquid chromatography (HPLC)	278:322	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	41	theme	liquid	295:300	arg1	microextraction					347:361	headspace-solid-phase microextraction	325:361	headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS)	325:436	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	3	42	dep	Neutrase	816:823	arg1	%					830:830	4.06%	826:830	4.06%	826:830	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	3	42	dep	Neutrase	816:823	arg1	%					840:840	2.09%	836:840	2.09%	836:840	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36175379	1	43	theme	mashing	180:186	arg1	efficiency					188:197	mashing efficiency	180:197	mashing efficiency	180:197	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	44	theme	Canadian	120:127	arg1	Malt					158:161	Malt 1	158:163	Malt 1	158:163	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	44	theme	Canadian	120:127	arg1	Malt					169:172	Malt 2	169:174	Malt 2	169:174	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	44	theme	Canadian	120:127	arg1	malts					151:155	Canadian and French commercial malts	120:155	Canadian and French commercial malts (Malt 1 and Malt 2)	120:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	4	45	theme	compounds	1009:1017	arg1	composition					1019:1029	compounds composition	1009:1029	compounds composition	1009:1029	HS-SPME-GC-MS showed that for Malt 1 and Malt 2, Neutrase not influenced the violate compounds composition, whereas reduced their contents.					
36175379	2	46	dep	increased	579:587	arg1	whereas					638:644	whereas	638:644	whereas	638:644	HPLC results showed that for Malt 1 containing lower free- and total-β-amylase but higher α-amylase enzyme activity, Neutrase significantly increased the content of maltose, glucose and maltotriose, whereas for Malt 2, only glucose content increased.					
36175379	1	47	theme	French	133:138	arg1	Malt					158:161	Malt 1	158:163	Malt 1	158:163	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	47	theme	French	133:138	arg1	Malt					169:172	Malt 2	169:174	Malt 2	169:174	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	1	47	theme	French	133:138	arg1	malts					151:155	Canadian and French commercial malts	120:155	Canadian and French commercial malts (Malt 1 and Malt 2)	120:175	The effects of malt protein removal by Neutrase using Canadian and French commercial malts (Malt 1 and Malt 2) on mashing efficiency, and production of violate compounds during fermentation were determined using high performance liquid chromatography (HPLC), headspace-solid-phase microextraction coupled with gas chromatography-mass spectrometry analysis (HS-SMPE-GC-MS).					
36175379	3	48	theme	ethanol	776:782	arg1	concentration					784:796	higher ethanol concentration	769:796	higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%)	769:841	For Malt 1, the increased glucose/maltose ratio after Neutrase addition led to higher ethanol concentration than that with no Neutrase (4.06% vs. 2.09%), whereas for Malt 2, no significant differences were observed (2.92% vs. 3.09%).					
36427578	4	0	theme	specific	824:831	arg1	area					841:844	specific surface area	824:844	specific surface area	824:844	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	4	1	with	area	888:891	arg1	material					934:941	the material	930:941	the material	930:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	9	2	theme	chitosan-biochar	1715:1730	arg1	material					1742:1749	the chitosan-biochar composite material	1711:1749	the chitosan-biochar composite material	1711:1749	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	8	3	theme	%	1548:1548	arg1	Nocardioides					1529:1540	Nocardioides	1529:1540	Nocardioides (26.79%-33.09%)	1529:1556	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	8	3	theme	%	1548:1548	arg1	%					1555:1555	26.79%-33.09%	1543:1555	26.79%-33.09%	1543:1555	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	6	4	theme	new	1201:1203	arg1	-NH-CO-					1219:1225	a new chemical bond -NH-CO-	1199:1225	a new chemical bond -NH-CO-	1199:1225	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	3	5	theme	chitosan	489:496	arg1	biochar					513:519	0.1% biochar	508:519	0.1% biochar	508:519	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	5	theme	chitosan	489:496	arg1	6 h					560:562	freeze-drying 6 h	546:562	freeze-drying 6 h	546:562	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	5	theme	chitosan	489:496	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	5	theme	chitosan	489:496	arg1	acid					474:477	1% (v/v) acetic acid	458:477	1% (v/v) acetic acid	458:477	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	5	theme	chitosan	489:496	arg1	solution					536:543	4% (v/v) NaOH solution	522:543	4% (v/v) NaOH solution	522:543	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	6	6	from	-COOH	1173:1177	arg1	biochar					1182:1188	biochar	1182:1188	biochar	1182:1188	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	4	7	theme	area	841:844	arg1	analysis					812:819	the analysis	808:819	the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material	808:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	7	8	theme	microorganism	1355:1367	arg1	method					1369:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	5	9	dep	adhered	987:993	arg1	the					960:962	the	960:962	the	960:962	SEM showed that the bacterial successfully adhered to the surface and internal of the material.					
36427578	2	10	theme	microbial	299:307	arg1	agent					309:313	a compound microbial agent	288:313	a compound microbial agent	288:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	7	11	theme	composite	1333:1341	arg1	method					1369:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	9	12	theme	high	1755:1758	arg1	value					1772:1776	high application value	1755:1776	high application value	1755:1776	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	2	13	dep	carrier	266:272	arg1	immobilize					277:286	immobilize	277:286	to immobilize a compound microbial agent	274:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	3	14	theme	%	511:511	arg1	biochar					513:519	0.1% biochar	508:519	0.1% biochar	508:519	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	14	theme	%	511:511	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	1	15	theme	microorganisms	191:204	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	15	theme	microorganisms	191:204	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	8	16	theme	%	1596:1596	arg1	Dietzia					1583:1589	Dietzia	1583:1589	Dietzia	1583:1589	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	8	16	theme	%	1596:1596	arg1	%					1602:1602	1.84%-5.56%	1592:1602	1.84%-5.56%	1592:1602	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	2	17	from	role	397:400	arg1	remediation					409:419	the remediation	405:419	the remediation of oil-contaminated soil	405:444	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	7	18	theme	crude	1303:1307	arg1	oil					1309:1311	crude oil	1303:1311	crude oil by chitosan-biochar composite immobilized microorganism method	1303:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	3	19	theme	%	523:523	arg1	solution					536:543	4% (v/v) NaOH solution	522:543	4% (v/v) NaOH solution	522:543	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	19	theme	%	523:523	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	4	20	theme	contact	880:886	arg1	area					888:891	the contact area	876:891	the contact area of microorganisms	876:909	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	4	21	theme	pore	850:853	arg1	size					855:858	pore size	850:858	pore size	850:858	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	0	22	from	bioremediation	71:84	arg1	soil					102:105	soil	102:105	soil	102:105	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	4	23	theme	material	664:671	arg1	surfacearea					645:655	The specific surfacearea	632:655	The specific surfacearea of the material	632:671	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	3	24	theme	NaOH	531:534	arg1	solution					536:543	4% (v/v) NaOH solution	522:543	4% (v/v) NaOH solution	522:543	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	24	theme	NaOH	531:534	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	7	25	theme	soil	1277:1280	arg1	remediation					1245:1255	remediation	1245:1255	remediation of oil-contaminated soil	1245:1280	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	6	26	theme	bond	1214:1217	arg1	-NH-CO-					1219:1225	a new chemical bond -NH-CO-	1199:1225	a new chemical bond -NH-CO-	1199:1225	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	6	27	theme	covalent	1128:1135	arg1	combination					1137:1147	the covalent combination	1124:1147	the covalent combination of -NH2	1124:1155	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	6	27	theme	covalent	1128:1135	arg1	synthesis					1080:1088	the synthesis	1076:1088	the synthesis of composite carrier material	1076:1118	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	9	28	theme	new	1824:1826	arg1	strategy					1828:1835	a new strategy	1822:1835	a new strategy for bioremediation of oil-contaminated soil	1822:1879	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	4	29	theme	specific	636:643	arg1	surfacearea					645:655	The specific surfacearea	632:655	The specific surfacearea of the material	632:671	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	6	30	from	chitosan	1160:1167	arg1	biochar					1182:1188	biochar	1182:1188	biochar	1182:1188	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	3	31	dep	%	523:523	arg1	v/v					526:528	v/v	526:528	v/v	526:528	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	0	32	theme	crude	89:93	arg1	oil					95:97	crude oil	89:97	crude oil	89:97	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	1	33	theme	friendly	170:177	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	33	theme	friendly	170:177	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	6	34	from	combination	1137:1147	arg1	-COOH					1173:1177	-COOH	1173:1177	-COOH	1173:1177	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	6	34	from	combination	1137:1147	arg1	chitosan					1160:1167	chitosan	1160:1167	chitosan	1160:1167	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	5	35	theme	material	1030:1037	arg1	adhered					987:993	adhered	987:993	adhered	987:993	SEM showed that the bacterial successfully adhered to the surface and internal of the material.					
36427578	3	36	dep	%	481:481	arg1	m/v					484:486	m/v	484:486	m/v	484:486	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	9	37	theme	soil	1876:1879	arg1	bioremediation					1841:1854	bioremediation	1841:1854	bioremediation of oil-contaminated soil	1841:1879	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	2	38	theme	oil-contaminated	424:439	arg1	soil					441:444	oil-contaminated soil	424:444	oil-contaminated soil	424:444	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	8	39	theme	exogenous	1664:1672	arg1	bacteria					1674:1681	exogenous bacteria	1664:1681	exogenous bacteria	1664:1681	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	7	40	theme	remediation	1245:1255	arg1	days					1237:1240	60 days	1234:1240	60 days of remediation of oil-contaminated soil	1234:1280	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	3	41	theme	1	458:458	arg1	%					459:459	%	459:459	%	459:459	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	4	42	theme	average	705:711	arg1	size					718:721	the average pore size	701:721	the average pore size	701:721	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	0	43	theme	chitosan-biochar	8:23	arg1	strategy					51:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	3	44	theme	0.1	508:510	arg1	%					511:511	%	511:511	%	511:511	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	8	45	theme	oil-degrading	1470:1482	arg1	bacteria					1484:1491	several oil-degrading bacteria	1462:1491	several oil-degrading bacteria	1462:1491	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	0	46	theme	microorganism	37:49	arg1	strategy					51:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	2	47	contain	contained	315:323	arg1	composite					251:259	the chitosan-biochar composite	230:259	the chitosan-biochar composite as a carrier to immobilize a compound microbial agent	230:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	2	47	contain	contained	315:323	arg2	aeruginosa					337:346	Pseudomonas aeruginosa	325:346	Pseudomonas aeruginosa	325:346	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	2	47	contain	contained	315:323	arg1	study					223:227	this study	218:227	this study	218:227	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	2	47	contain	contained	315:323	arg2	licheniformis					361:373	Bacillus licheniformis	352:373	Bacillus licheniformis	352:373	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	2	47	contain	contained	315:323	arg2	composite					251:259	the chitosan-biochar composite	230:259	the chitosan-biochar composite as a carrier to immobilize a compound microbial agent	230:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	7	48	theme	natural	1425:1431	arg1	remediation					1433:1443	natural remediation	1425:1443	natural remediation	1425:1443	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	3	49	dep	%	459:459	arg1	v/v					462:464	v/v	462:464	v/v	462:464	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	50	theme	chitosan-biochar	577:592	arg1	material					604:611	the optimal chitosan-biochar composite material	565:611	the optimal chitosan-biochar composite material	565:611	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	4	51	with	oil	921:923	arg1	material					934:941	the material	930:941	the material	930:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	8	52	theme	genus	1506:1510	arg1	level					1512:1516	genus level	1506:1516	genus level	1506:1516	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	3	53	theme	3	480:480	arg1	%					481:481	%	481:481	%	481:481	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	6	54	theme	composite	1093:1101	arg1	material					1111:1118	composite carrier material	1093:1118	composite carrier material	1093:1118	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	3	55	theme	acetic	467:472	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	55	theme	acetic	467:472	arg1	acid					474:477	1% (v/v) acetic acid	458:477	1% (v/v) acetic acid	458:477	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	6	56	theme	chemical	1205:1212	arg1	-NH-CO-					1219:1225	a new chemical bond -NH-CO-	1199:1225	a new chemical bond -NH-CO-	1199:1225	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	9	57	theme	composite	1732:1740	arg1	material					1742:1749	the chitosan-biochar composite material	1711:1749	the chitosan-biochar composite material	1711:1749	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	9	58	contain	has	1751:1753	arg2	value					1772:1776	high application value	1755:1776	high application value	1755:1776	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	9	58	contain	has	1751:1753	arg1	material					1742:1749	the chitosan-biochar composite material	1711:1749	the chitosan-biochar composite material	1711:1749	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	4	59	theme	surface	833:839	arg1	area					841:844	specific surface area	824:844	specific surface area	824:844	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	6	60	theme	material	1111:1118	arg1	synthesis					1080:1088	the synthesis	1076:1088	the synthesis of composite carrier material	1076:1118	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	6	60	theme	material	1111:1118	arg1	combination					1137:1147	the covalent combination	1124:1147	the covalent combination of -NH2	1124:1155	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	2	61	theme	compound	290:297	arg1	agent					309:313	a compound microbial agent	288:313	a compound microbial agent	288:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	1	62	theme	immobilized	179:189	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	62	theme	immobilized	179:189	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	4	63	theme	biochar	792:798	arg1	addition					780:787	the addition	776:787	the addition of biochar	776:798	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	7	64	theme	immobilized	1343:1353	arg1	method					1369:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	9	65	theme	application	1760:1770	arg1	value					1772:1776	high application value	1755:1776	high application value	1755:1776	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	7	66	theme	chitosan-biochar	1316:1331	arg1	method					1369:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	chitosan-biochar composite immobilized microorganism method	1316:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	3	67	theme	4	522:522	arg1	%					523:523	%	523:523	%	523:523	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	8	68	theme	1.84	1592:1595	arg1	Dietzia					1583:1589	Dietzia	1583:1589	Dietzia	1583:1589	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	8	68	theme	1.84	1592:1595	arg1	%					1602:1602	1.84%-5.56%	1592:1602	1.84%-5.56%	1592:1602	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	7	69	theme	oil	1309:1311	arg1	%					1385:1385	45.82%	1380:1385	45.82%	1380:1385	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	7	69	theme	oil	1309:1311	arg1	rate					1295:1298	the removal rate	1283:1298	the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method	1283:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	9	70	theme	crude	1790:1794	arg1	oil					1796:1798	crude oil	1790:1798	crude oil	1790:1798	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	5	71	dep	showed	948:953	arg1	internal					1014:1021	internal	1014:1021	internal	1014:1021	SEM showed that the bacterial successfully adhered to the surface and internal of the material.					
36427578	5	71	dep	showed	948:953	arg1	adhered					987:993	adhered	987:993	adhered	987:993	SEM showed that the bacterial successfully adhered to the surface and internal of the material.					
36427578	2	72	theme	chitosan-biochar	234:249	arg1	composite					251:259	the chitosan-biochar composite	230:259	the chitosan-biochar composite as a carrier to immobilize a compound microbial agent	230:313	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	1	73	theme	chitosan-biochar	112:127	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	73	theme	chitosan-biochar	112:127	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	7	74	theme	removal	1287:1293	arg1	%					1385:1385	45.82%	1380:1385	45.82%	1380:1385	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	7	74	theme	removal	1287:1293	arg1	rate					1295:1298	the removal rate	1283:1298	the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method	1283:1374	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	6	75	theme	-NH2	1152:1155	arg1	combination					1137:1147	the covalent combination	1124:1147	the covalent combination of -NH2	1124:1155	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	6	75	theme	-NH2	1152:1155	arg1	synthesis					1080:1088	the synthesis	1076:1088	the synthesis of composite carrier material	1076:1118	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	4	76	theme	size	855:858	arg1	analysis					812:819	the analysis	808:819	the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material	808:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	3	77	theme	freeze-drying	546:558	arg1	6 h					560:562	freeze-drying 6 h	546:562	freeze-drying 6 h	546:562	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	77	theme	freeze-drying	546:558	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	1	78	theme	clean	144:148	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	78	theme	clean	144:148	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	4	79	theme	crude	915:919	arg1	oil					921:923	crude oil	915:923	crude oil with the material	915:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	7	80	theme	oil-contaminated	1260:1275	arg1	soil					1277:1280	oil-contaminated soil	1260:1280	oil-contaminated soil	1260:1280	After 60 days of remediation of oil-contaminated soil, the removal rate of crude oil by chitosan-biochar composite immobilized microorganism method was 45.82%, which was 21.26% higher than that of natural remediation.					
36427578	0	81	theme	oil	95:97	arg1	bioremediation					71:84	bioremediation	71:84	bioremediation of crude oil in soil	71:105	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	1	82	theme	environmentally	154:168	arg1	carrier					206:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	a clean and environmentally friendly immobilized microorganisms carrier	142:212	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	1	82	theme	environmentally	154:168	arg1	composite					129:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite	108:137	The chitosan-biochar composite is a clean and environmentally friendly immobilized microorganisms carrier.					
36427578	9	83	theme	oil-contaminated	1859:1874	arg1	soil					1876:1879	oil-contaminated soil	1859:1879	oil-contaminated soil	1859:1879	The results indicated that the chitosan-biochar composite material has high application value in removing crude oil, and further provides a new strategy for bioremediation of oil-contaminated soil.					
36427578	4	84	theme	pore	713:716	arg1	size					718:721	the average pore size	701:721	the average pore size	701:721	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	4	85	theme	microorganisms	896:909	arg1	oil					921:923	crude oil	915:923	crude oil with the material	915:941	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	4	85	theme	microorganisms	896:909	arg1	area					888:891	the contact area	876:891	the contact area of microorganisms	876:909	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	0	86	theme	novel	2:6	arg1	strategy					51:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	8	87	theme	several	1462:1468	arg1	bacteria					1484:1491	several oil-degrading bacteria	1462:1491	several oil-degrading bacteria	1462:1491	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	3	88	theme	%	459:459	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	88	theme	%	459:459	arg1	acid					474:477	1% (v/v) acetic acid	458:477	1% (v/v) acetic acid	458:477	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	0	89	theme	immobilized	25:35	arg1	strategy					51:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy	0:58	A novel chitosan-biochar immobilized microorganism strategy to enhance bioremediation of crude oil in soil.					
36427578	3	90	theme	composite	594:602	arg1	material					604:611	the optimal chitosan-biochar composite material	565:611	the optimal chitosan-biochar composite material	565:611	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	91	theme	optimal	569:575	arg1	material					604:611	the optimal chitosan-biochar composite material	565:611	the optimal chitosan-biochar composite material	565:611	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	2	92	theme	soil	441:444	arg1	remediation					409:419	the remediation	405:419	the remediation of oil-contaminated soil	405:444	In this study, the chitosan-biochar composite as a carrier to immobilize a compound microbial agent contained Pseudomonas aeruginosa and Bacillus licheniformis, and investigated its role in the remediation of oil-contaminated soil.					
36427578	4	93	dep	165.2980 nm	758:768	arg1	130.2260 nm					743:753	130.2260 nm	743:753	130.2260 nm	743:753	The specific surfacearea of the material increased to 1.725 m2/g and the average pore size also increased from 130.2260 nm to 165.2980 nm after the addition of biochar through the analysis of specific surface area and pore size, which enlarged the contact area of microorganisms and crude oil with the material.					
36427578	3	94	theme	%	481:481	arg1	biochar					513:519	0.1% biochar	508:519	0.1% biochar	508:519	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	94	theme	%	481:481	arg1	6 h					560:562	freeze-drying 6 h	546:562	freeze-drying 6 h	546:562	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	94	theme	%	481:481	arg1	solution					498:505	3% (m/v) chitosan solution	480:505	3% (m/v) chitosan solution	480:505	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	94	theme	%	481:481	arg1	acid					474:477	1% (v/v) acetic acid	458:477	1% (v/v) acetic acid	458:477	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	3	94	theme	%	481:481	arg1	solution					536:543	4% (v/v) NaOH solution	522:543	4% (v/v) NaOH solution	522:543	When using 1% (v/v) acetic acid, 3% (m/v) chitosan solution, 0.1% biochar, 4% (v/v) NaOH solution, freeze-drying 6 h, the optimal chitosan-biochar composite material could be obtained.					
36427578	6	95	theme	carrier	1103:1109	arg1	material					1111:1118	composite carrier material	1093:1118	composite carrier material	1093:1118	Using FTIR, the results showed that the synthesis of composite carrier material was the covalent combination of -NH2 on chitosan and -COOH on biochar, forming a new chemical bond -NH-CO-.					
36427578	8	96	theme	%	1573:1573	arg1	Bacillus					1559:1566	Bacillus	1559:1566	Bacillus (3.01%-4.10%)	1559:1580	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36427578	8	96	theme	%	1573:1573	arg1	%					1579:1579	3.01%-4.10%	1569:1579	3.01%-4.10%	1569:1579	Simultaneously, several oil-degrading bacteria increased at genus level, including Nocardioides (26.79%-33.09%), Bacillus (3.01%-4.10%), Dietzia (1.84%-5.56%), Pseudomonas (0-0.78%), among which Pseudomonas belongs to exogenous bacteria.					
36565040	10	0	from	hDPSCs	1844:1849	arg1	day					1854:1856	day 21	1854:1859	day 21	1854:1859	CSHA significantly upregulated VEGF and DSPP levels on hDPSCs on day 21 compared with day 7 (p < .05).					
36565040	15	1	theme	effective	2509:2517	arg1	agent					2532:2536	an effective pulp capping agent	2506:2536	an effective pulp capping agent	2506:2536	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	8	2	theme	HAp	1630:1632	arg1	CMC					1638:1640	CMC	1638:1640	CMC	1638:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	2	theme	HAp	1630:1632	arg1	groups					1615:1620	the characteristic functional groups	1585:1620	the characteristic functional groups of both HAp and CMC	1585:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	2	theme	HAp	1630:1632	arg1	HAp					1630:1632	HAp	1630:1632	HAp	1630:1632	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	3	3	theme	scanning	541:548	arg1	microscopy					559:568	scanning electron microscopy	541:568	scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy	541:673	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	15	4	theme	in-vivo	2591:2597	arg1	studies					2606:2612	in-vivo animal studies	2591:2612	in-vivo animal studies	2591:2612	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	12	5	theme	increased	2041:2049	arg1	ALP					2051:2053	increased ALP and ARS activity	2041:2070	ALP	2051:2053	However, CSHA exhibited increased ALP and ARS activity with an intense OPN staining compared with Biodentine after 14 days (p < .05).					
36565040	6	6	theme	Red	1187:1189	arg1	ARS					1201:1203	ARS	1201:1203	ARS	1201:1203	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	6	6	theme	Red	1187:1189	arg1	Staining					1191:1198	Alizarin Red Staining	1178:1198	Alizarin Red Staining (ARS)	1178:1204	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	5	7	theme	odontogenic	799:809	arg1	abilities					827:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	14	8	theme	mineralization	2352:2365	arg1	activity					2367:2374	enhanced mineralization activity	2343:2374	enhanced mineralization activity	2343:2374	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	14	9	theme	OPN	2432:2434	arg1	activity					2436:2443	increased ALP, ARS and OPN activity	2409:2443	increased ALP, ARS and OPN activity on day 14	2409:2453	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	7	10	theme	post	1395:1398	arg1	p < .05					1411:1417	p < .05	1411:1417	p < .05	1411:1417	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	7	10	theme	post	1395:1398	arg1	tests					1404:1408	appropriate post hoc tests	1383:1408	appropriate post hoc tests (p < .05)	1383:1418	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	1	11	from	Biodentine	286:295	arg1	hDPSCs					330:335	hDPSCs	330:335	hDPSCs	330:335	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	11	from	Biodentine	286:295	arg1	cells					323:327	human dental pulp stem cells	300:327	human dental pulp stem cells (hDPSCs)	300:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	13	12	theme	CSHA	2253:2256	arg1	differentiation					2202:2216	the odontogenic differentiation and biomineralization abilities	2186:2248	differentiation	2202:2216	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	13	12	theme	CSHA	2253:2256	arg1	abilities					2240:2248	the odontogenic differentiation and biomineralization abilities	2186:2248	abilities	2240:2248	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	3	13	theme	energy-dispersive	575:591	arg1	spectroscopy					599:610	energy-dispersive X-ray spectroscopy	575:610	energy-dispersive X-ray spectroscopy	575:610	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	5	14	theme	vascular	868:875	arg1	VEGF					904:907	VEGF	904:907	VEGF	904:907	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	14	theme	vascular	868:875	arg1	DSPP					943:946	DSPP	943:946	DSPP	943:946	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	14	theme	vascular	868:875	arg1	factor					896:901	vascular endothelial growth factor	868:901	vascular endothelial growth factor (VEGF)	868:908	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	9	15	from	bioactivity	1658:1668	arg1	SBF					1673:1675	SBF	1673:1675	SBF	1673:1675	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	9	16	theme	apatite-like	1688:1699	arg1	crystals					1701:1708	apatite-like crystals	1688:1708	apatite-like crystals	1688:1708	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	4	17	theme	In-vitro	676:683	arg1	bioactivity					685:695	In-vitro bioactivity and pH assessments	676:714	bioactivity	685:695	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	3	18	theme	X-ray	613:617	arg1	diffraction					619:629	X-ray diffraction	613:629	X-ray diffraction	613:629	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	5	19	theme	growth	889:894	arg1	VEGF					904:907	VEGF	904:907	VEGF	904:907	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	19	theme	growth	889:894	arg1	DSPP					943:946	DSPP	943:946	DSPP	943:946	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	19	theme	growth	889:894	arg1	factor					896:901	vascular endothelial growth factor	868:901	vascular endothelial growth factor (VEGF)	868:908	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	8	20	theme	Characterization	1429:1444	arg1	experiments					1446:1456	RESULTS Characterization experiments	1421:1456	RESULTS Characterization experiments	1421:1456	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	4	21	theme	simulated	740:748	arg1	SBF					762:764	SBF	762:764	SBF	762:764	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	4	21	theme	simulated	740:748	arg1	fluid					755:759	simulated body fluid	740:759	simulated body fluid (SBF) for 28 days	740:777	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	9	22	dep	in	1771:1772	arg1	vitro					1774:1778	vitro	1774:1778	vitro	1774:1778	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	9	23	dep	28 days	1762:1768	arg1	studies					1780:1786	in vitro studies	1771:1786	28 days' in vitro studies	1762:1786	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	10	24	theme	VEGF	1820:1823	arg1	levels					1834:1839	VEGF and DSPP levels	1820:1839	levels	1834:1839	CSHA significantly upregulated VEGF and DSPP levels on hDPSCs on day 21 compared with day 7 (p < .05).					
36565040	1	25	theme	differentiation	150:164	arg1	potential					166:174	the odontogenic differentiation potential	134:174	the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs)	134:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	6	26	theme	Cell	1028:1031	arg1	viability/proliferation					1033:1055	Cell viability/proliferation and biomineralization abilities	1028:1087	viability/proliferation	1033:1055	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	9	27	theme	pH	1738:1739	arg1	value					1741:1745	a consistent pH value	1725:1745	a consistent pH value of 7.70	1725:1753	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	8	28	theme	porous	1469:1474	arg1	microstructure					1476:1489	a porous microstructure	1467:1489	a porous microstructure of CSHA	1467:1497	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	0	29	theme	human	89:93	arg1	cells					112:116	human dental pulp stem cells	89:116	human dental pulp stem cells	89:116	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	5	30	theme	Dentine	914:920	arg1	sialophosphoprotein					922:940	Dentine sialophosphoprotein	914:940	Dentine sialophosphoprotein	914:940	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	31	theme	angiogenic	784:793	arg1	abilities					827:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	1	32	theme	composite	181:189	arg1	CSHA					201:204	CSHA	201:204	CSHA	201:204	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	32	theme	composite	181:189	arg1	scaffold					191:198	a composite scaffold	179:198	a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs)	179:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	11	33	theme	statistical	1982:1992	arg1	p > .05					2007:2013	p > .05	2007:2013	p > .05	2007:2013	Further, CSHA supported cell viability/proliferation over 14 days like Biodentine with no statistical differences (p > .05).					
36565040	11	33	theme	statistical	1982:1992	arg1	differences					1994:2004	no statistical differences	1979:2004	no statistical differences (p > .05)	1979:2014	Further, CSHA supported cell viability/proliferation over 14 days like Biodentine with no statistical differences (p > .05).					
36565040	13	34	theme	significant	2273:2283	arg1	VEGF					2285:2288	significant VEGF	2273:2288	significant VEGF	2273:2288	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	13	35	from	differentiation	2202:2216	arg1	hDPSCs					2261:2266	hDPSCs	2261:2266	hDPSCs with significant VEGF and DSPP gene upregulations	2261:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	11	36	with	Biodentine	1963:1972	arg1	p > .05					2007:2013	p > .05	2007:2013	p > .05	2007:2013	Further, CSHA supported cell viability/proliferation over 14 days like Biodentine with no statistical differences (p > .05).					
36565040	11	36	with	Biodentine	1963:1972	arg1	differences					1994:2004	no statistical differences	1979:2004	no statistical differences (p > .05)	1979:2014	Further, CSHA supported cell viability/proliferation over 14 days like Biodentine with no statistical differences (p > .05).					
36565040	5	37	from	markers	949:955	arg1	hDPSCs					969:974	cultured hDPSCs	960:974	cultured hDPSCs	960:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	7	38	theme	Friedman	1331:1338	arg1	tests					1340:1344	Friedman tests	1331:1344	Friedman tests	1331:1344	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	3	39	with	microscopy	559:568	arg1	Fourier					635:641	Fourier	635:641	Fourier transform infrared spectroscopy	635:673	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	3	39	with	microscopy	559:568	arg1	spectroscopy					599:610	energy-dispersive X-ray spectroscopy	575:610	energy-dispersive X-ray spectroscopy	575:610	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	3	39	with	microscopy	559:568	arg1	diffraction					619:629	X-ray diffraction	613:629	X-ray diffraction	613:629	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	13	40	with	hDPSCs	2261:2266	arg1	VEGF					2285:2288	significant VEGF	2273:2288	significant VEGF	2273:2288	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	13	40	with	hDPSCs	2261:2266	arg1	upregulations					2304:2316	DSPP gene upregulations	2294:2316	DSPP gene upregulations	2294:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	6	41	theme	CSHA	1092:1095	arg1	abilities					1079:1087	Cell viability/proliferation and biomineralization abilities	1028:1087	abilities	1079:1087	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	6	41	theme	CSHA	1092:1095	arg1	viability/proliferation					1033:1055	Cell viability/proliferation and biomineralization abilities	1028:1087	viability/proliferation	1033:1055	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	0	42	theme	nano-hydroxyapatite	20:38	arg1	Characterization					0:15	Characterization	0:15	Characterization of nano-hydroxyapatite	0:38	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	5	43	theme	flow	979:982	arg1	cytometry					984:992	flow cytometry	979:992	flow cytometry	979:992	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	13	44	theme	DSPP	2294:2297	arg1	upregulations					2304:2316	DSPP gene upregulations	2294:2316	DSPP gene upregulations	2294:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	5	45	theme	factor	896:901	arg1	markers					949:955	vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers	868:955	vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs	868:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	1	46	theme	dental	306:311	arg1	hDPSCs					330:335	hDPSCs	330:335	hDPSCs	330:335	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	46	theme	dental	306:311	arg1	cells					323:327	human dental pulp stem cells	300:327	human dental pulp stem cells (hDPSCs)	300:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	0	47	theme	carboxymethyl	53:65	arg1	composite					76:84	carboxymethyl chitosan composite	53:84	carboxymethyl chitosan composite	53:84	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	8	48	theme	Ca/P	1557:1560	arg1	ratio					1568:1572	1.67 Ca/P molar ratio	1552:1572	1.67 Ca/P molar ratio	1552:1572	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	10	49	theme	DSPP	1829:1832	arg1	levels					1834:1839	VEGF and DSPP levels	1820:1839	levels	1834:1839	CSHA significantly upregulated VEGF and DSPP levels on hDPSCs on day 21 compared with day 7 (p < .05).					
36565040	6	50	dep	assay	1134:1138	arg1	expression					1228:1237	expression	1228:1237	expression on hDPSCs following 7 and 14 days	1228:1271	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	14	51	theme	ARS	2424:2426	arg1	activity					2436:2443	increased ALP, ARS and OPN activity	2409:2443	increased ALP, ARS and OPN activity on day 14	2409:2453	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	1	52	theme	stem	318:321	arg1	hDPSCs					330:335	hDPSCs	330:335	hDPSCs	330:335	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	52	theme	stem	318:321	arg1	cells					323:327	human dental pulp stem cells	300:327	human dental pulp stem cells (hDPSCs)	300:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	6	53	theme	phosphatase	1150:1160	arg1	activity					1168:1175	alkaline phosphatase (ALP) activity	1141:1175	alkaline phosphatase (ALP) activity	1141:1175	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	14	54	theme	ALP	2419:2421	arg1	activity					2436:2443	increased ALP, ARS and OPN activity	2409:2443	increased ALP, ARS and OPN activity on day 14	2409:2453	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	3	55	theme	Physicochemical	489:503	arg1	characterization					505:520	Physicochemical characterization	489:520	Physicochemical characterization	489:520	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	5	56	from	hDPSCs	969:974	arg1	expression					854:863	expression	854:863	expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs	854:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	6	57	theme	MTT	1130:1132	arg1	assay					1134:1138	MTT assay	1130:1138	MTT assay	1130:1138	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	8	58	theme	characteristic	1589:1602	arg1	CMC					1638:1640	CMC	1638:1640	CMC	1638:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	58	theme	characteristic	1589:1602	arg1	groups					1615:1620	the characteristic functional groups	1585:1620	the characteristic functional groups of both HAp and CMC	1585:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	58	theme	characteristic	1589:1602	arg1	HAp					1630:1632	HAp	1630:1632	HAp	1630:1632	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	15	59	theme	pulp	2519:2522	arg1	agent					2532:2536	an effective pulp capping agent	2506:2536	an effective pulp capping agent	2506:2536	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	13	60	from	abilities	2240:2248	arg1	hDPSCs					2261:2266	hDPSCs	2261:2266	hDPSCs with significant VEGF and DSPP gene upregulations	2261:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	15	61	theme	animal	2599:2604	arg1	studies					2606:2612	in-vivo animal studies	2591:2612	in-vivo animal studies	2591:2612	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	1	62	theme	scaffold	191:198	arg1	potential					166:174	the odontogenic differentiation potential	134:174	the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs)	134:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	6	63	theme	Alizarin	1178:1185	arg1	ARS					1201:1203	ARS	1201:1203	ARS	1201:1203	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	6	63	theme	Alizarin	1178:1185	arg1	Staining					1191:1198	Alizarin Red Staining	1178:1198	Alizarin Red Staining (ARS)	1178:1204	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	12	64	theme	intense	2080:2086	arg1	staining					2092:2099	an intense OPN staining	2077:2099	an intense OPN staining compared with Biodentine after 14 days (p < .05)	2077:2148	However, CSHA exhibited increased ALP and ARS activity with an intense OPN staining compared with Biodentine after 14 days (p < .05).					
36565040	15	65	contain	has	2478:2480	arg1	scaffold					2469:2476	The nHAp-CMC scaffold	2456:2476	The nHAp-CMC scaffold	2456:2476	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	15	65	contain	has	2478:2480	arg2	potential					2486:2494	the potential to act as an effective pulp capping agent	2482:2536	the potential to act as an effective pulp capping agent	2482:2536	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	9	66	theme	7.70	1750:1753	arg1	value					1741:1745	a consistent pH value	1725:1745	a consistent pH value of 7.70	1725:1753	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	14	67	theme	enhanced	2343:2350	arg1	activity					2367:2374	enhanced mineralization activity	2343:2374	enhanced mineralization activity	2343:2374	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	7	68	theme	hoc	1400:1402	arg1	p < .05					1411:1417	p < .05	1411:1417	p < .05	1411:1417	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	7	68	theme	hoc	1400:1402	arg1	tests					1404:1408	appropriate post hoc tests	1383:1408	appropriate post hoc tests (p < .05)	1383:1418	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	4	69	theme	pH	701:702	arg1	assessments					704:714	In-vitro bioactivity and pH assessments	676:714	assessments	704:714	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	3	70	theme	electron	550:557	arg1	microscopy					559:568	scanning electron microscopy	541:568	scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy	541:673	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	8	71	theme	RESULTS	1421:1427	arg1	experiments					1446:1456	RESULTS Characterization experiments	1421:1456	RESULTS Characterization experiments	1421:1456	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	7	72	theme	appropriate	1383:1393	arg1	p < .05					1411:1417	p < .05	1411:1417	p < .05	1411:1417	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	7	72	theme	appropriate	1383:1393	arg1	tests					1404:1408	appropriate post hoc tests	1383:1408	appropriate post hoc tests (p < .05)	1383:1418	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	12	73	theme	ARS	2059:2061	arg1	activity					2063:2070	increased ALP and ARS activity	2041:2070	activity	2063:2070	However, CSHA exhibited increased ALP and ARS activity with an intense OPN staining compared with Biodentine after 14 days (p < .05).					
36565040	5	74	theme	endothelial	877:887	arg1	VEGF					904:907	VEGF	904:907	VEGF	904:907	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	74	theme	endothelial	877:887	arg1	DSPP					943:946	DSPP	943:946	DSPP	943:946	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	74	theme	endothelial	877:887	arg1	factor					896:901	vascular endothelial growth factor	868:901	vascular endothelial growth factor (VEGF)	868:908	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	3	75	theme	X-ray	593:597	arg1	spectroscopy					599:610	energy-dispersive X-ray spectroscopy	575:610	energy-dispersive X-ray spectroscopy	575:610	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	15	76	theme	nHAp-CMC	2460:2467	arg1	scaffold					2469:2476	The nHAp-CMC scaffold	2456:2476	The nHAp-CMC scaffold	2456:2476	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	7	77	theme	way	1361:1363	arg1	anova					1365:1369	one way anova	1357:1369	one way anova followed by appropriate post hoc tests (p < .05)	1357:1418	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	13	78	theme	gene	2299:2302	arg1	upregulations					2304:2316	DSPP gene upregulations	2294:2316	DSPP gene upregulations	2294:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	1	79	theme	odontogenic	138:148	arg1	potential					166:174	the odontogenic differentiation potential	134:174	the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs)	134:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	9	80	theme	consistent	1727:1736	arg1	value					1741:1745	a consistent pH value	1725:1745	a consistent pH value of 7.70	1725:1753	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	4	81	theme	body	750:753	arg1	SBF					762:764	SBF	762:764	SBF	762:764	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	4	81	theme	body	750:753	arg1	fluid					755:759	simulated body fluid	740:759	simulated body fluid (SBF) for 28 days	740:777	In-vitro bioactivity and pH assessments were done by soaking in simulated body fluid (SBF) for 28 days.					
36565040	6	82	from	expression	1228:1237	arg1	14 days					1265:1271	14 days	1265:1271	14 days	1265:1271	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	6	82	from	expression	1228:1237	arg1	hDPSCs					1242:1247	hDPSCs	1242:1247	hDPSCs following 7	1242:1259	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	0	83	theme	dental	95:100	arg1	cells					112:116	human dental pulp stem cells	89:116	human dental pulp stem cells	89:116	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	13	84	theme	biomineralization	2222:2238	arg1	abilities					2240:2248	the odontogenic differentiation and biomineralization abilities	2186:2248	abilities	2240:2248	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	8	85	theme	CSHA	1494:1497	arg1	microstructure					1476:1489	a porous microstructure	1467:1489	a porous microstructure of CSHA	1467:1497	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	0	86	theme	stem	107:110	arg1	cells					112:116	human dental pulp stem cells	89:116	human dental pulp stem cells	89:116	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	5	87	theme	sialophosphoprotein	922:940	arg1	markers					949:955	vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers	868:955	vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs	868:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	2	88	theme	water	449:453	arg1	medium					455:460	water medium	449:460	water medium followed by freeze-drying	449:486	METHODOLOGY A CSHA scaffold was prepared through an ultrasonication route by adding nHAp and CMC (1:5 w/w) in water medium followed by freeze-drying.					
36565040	8	89	theme	pore	1504:1507	arg1	diameter					1509:1516	pore diameter	1504:1516	pore diameter ranging between 60 and 200 μm	1504:1546	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	2	90	dep	METHODOLOGY	339:349	arg1	scaffold					358:365	A CSHA scaffold	351:365	METHODOLOGY A CSHA scaffold	339:365	METHODOLOGY A CSHA scaffold was prepared through an ultrasonication route by adding nHAp and CMC (1:5 w/w) in water medium followed by freeze-drying.					
36565040	5	91	from	expression	854:863	arg1	hDPSCs					969:974	cultured hDPSCs	960:974	cultured hDPSCs	960:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	5	92	theme	markers	949:955	arg1	expression					854:863	expression	854:863	expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs	854:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	9	93	theme	in	1771:1772	arg1	studies					1780:1786	in vitro studies	1771:1786	28 days' in vitro studies	1762:1786	CSHA displayed bioactivity in SBF by forming apatite-like crystals and maintained a consistent pH value of 7.70 during 28 days' in vitro studies.					
36565040	13	94	dep	CONCLUSION	2151:2160	arg1	highlighted					2174:2184	highlighted	2174:2184	highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations	2174:2316	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	5	95	theme	cultured	960:967	arg1	hDPSCs					969:974	cultured hDPSCs	960:974	cultured hDPSCs	960:974	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	7	96	theme	Kruskal	1312:1318	arg1	Wallis					1320:1325	Kruskal Wallis	1312:1325	Kruskal Wallis	1312:1325	Data were statistically analysed with Kruskal Wallis and Friedman tests as well as one way anova followed by appropriate post hoc tests (p < .05).					
36565040	14	97	from	activity	2436:2443	arg1	day					2448:2450	day 14	2448:2453	day 14	2448:2453	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	13	98	theme	odontogenic	2190:2200	arg1	differentiation					2202:2216	the odontogenic differentiation and biomineralization abilities	2186:2248	differentiation	2202:2216	CONCLUSION The results highlighted the odontogenic differentiation and biomineralization abilities of CSHA on hDPSCs with significant VEGF and DSPP gene upregulations.					
36565040	0	99	theme	chitosan	67:74	arg1	composite					76:84	carboxymethyl chitosan composite	53:84	carboxymethyl chitosan composite	53:84	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	1	100	theme	human	300:304	arg1	hDPSCs					330:335	hDPSCs	330:335	hDPSCs	330:335	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	100	theme	human	300:304	arg1	cells					323:327	human dental pulp stem cells	300:327	human dental pulp stem cells (hDPSCs)	300:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	3	101	dep	Fourier	635:641	arg1	transform					643:651	transform	643:651	transform infrared spectroscopy	643:673	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	6	102	theme	biomineralization	1061:1077	arg1	abilities					1079:1087	Cell viability/proliferation and biomineralization abilities	1028:1087	abilities	1079:1087	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	8	103	theme	molar	1562:1566	arg1	ratio					1568:1572	1.67 Ca/P molar ratio	1552:1572	1.67 Ca/P molar ratio	1552:1572	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	2	104	theme	ultrasonication	391:405	arg1	route					407:411	an ultrasonication route	388:411	an ultrasonication route	388:411	METHODOLOGY A CSHA scaffold was prepared through an ultrasonication route by adding nHAp and CMC (1:5 w/w) in water medium followed by freeze-drying.					
36565040	5	105	theme	differentiation	811:825	arg1	abilities					827:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities	780:835	The angiogenic and odontogenic differentiation abilities were assessed by expression of vascular endothelial growth factor (VEGF) and Dentine sialophosphoprotein (DSPP) markers on cultured hDPSCs by flow cytometry and RT-qPCR at 7, 14 and 21 days.					
36565040	1	106	theme	pulp	313:316	arg1	hDPSCs					330:335	hDPSCs	330:335	hDPSCs	330:335	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	106	theme	pulp	313:316	arg1	cells					323:327	human dental pulp stem cells	300:327	human dental pulp stem cells (hDPSCs)	300:336	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	12	107	theme	OPN	2088:2090	arg1	staining					2092:2099	an intense OPN staining	2077:2099	an intense OPN staining compared with Biodentine after 14 days (p < .05)	2077:2148	However, CSHA exhibited increased ALP and ARS activity with an intense OPN staining compared with Biodentine after 14 days (p < .05).					
36565040	8	108	theme	CMC	1638:1640	arg1	CMC					1638:1640	CMC	1638:1640	CMC	1638:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	108	theme	CMC	1638:1640	arg1	groups					1615:1620	the characteristic functional groups	1585:1620	the characteristic functional groups of both HAp and CMC	1585:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	108	theme	CMC	1638:1640	arg1	HAp					1630:1632	HAp	1630:1632	HAp	1630:1632	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	11	109	theme	cell	1916:1919	arg1	viability/proliferation					1921:1943	cell viability/proliferation	1916:1943	cell viability/proliferation	1916:1943	Further, CSHA supported cell viability/proliferation over 14 days like Biodentine with no statistical differences (p > .05).					
36565040	6	110	theme	alkaline	1141:1148	arg1	ALP					1163:1165	ALP	1163:1165	ALP	1163:1165	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	6	110	theme	alkaline	1141:1148	arg1	phosphatase					1150:1160	alkaline phosphatase	1141:1160	alkaline phosphatase (ALP) activity	1141:1175	Cell viability/proliferation and biomineralization abilities of CSHA were compared with Biodentine by MTT assay, alkaline phosphatase (ALP) activity, Alizarin Red Staining (ARS) and osteopontin (OPN) expression on hDPSCs following 7 and 14 days.					
36565040	14	111	theme	increased	2409:2417	arg1	activity					2436:2443	increased ALP, ARS and OPN activity	2409:2443	increased ALP, ARS and OPN activity on day 14	2409:2453	Further, CSHA exhibited enhanced mineralization activity than Biodentine, as evidenced by increased ALP, ARS and OPN activity on day 14.					
36565040	3	112	dep	transform	643:651	arg1	infrared					653:660	infrared	653:660	transform infrared spectroscopy	643:673	Physicochemical characterization was achieved using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy.					
36565040	8	113	theme	functional	1604:1613	arg1	CMC					1638:1640	CMC	1638:1640	CMC	1638:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	113	theme	functional	1604:1613	arg1	groups					1615:1620	the characteristic functional groups	1585:1620	the characteristic functional groups of both HAp and CMC	1585:1640	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	8	113	theme	functional	1604:1613	arg1	HAp					1630:1632	HAp	1630:1632	HAp	1630:1632	RESULTS Characterization experiments revealed a porous microstructure of CSHA with pore diameter ranging between 60 and 200 μm and 1.67 Ca/P molar ratio along with the characteristic functional groups of both HAp and CMC.					
36565040	0	114	theme	pulp	102:105	arg1	cells					112:116	human dental pulp stem cells	89:116	human dental pulp stem cells	89:116	Characterization of nano-hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells.					
36565040	2	115	theme	CSHA	353:356	arg1	scaffold					358:365	A CSHA scaffold	351:365	METHODOLOGY A CSHA scaffold	339:365	METHODOLOGY A CSHA scaffold was prepared through an ultrasonication route by adding nHAp and CMC (1:5 w/w) in water medium followed by freeze-drying.					
36565040	15	116	theme	capping	2524:2530	arg1	agent					2532:2536	an effective pulp capping agent	2506:2536	an effective pulp capping agent	2506:2536	The nHAp-CMC scaffold has the potential to act as an effective pulp capping agent; however, this needs to be further validated through in-vivo animal studies.					
36565040	1	117	theme	carboxymethyl	252:264	arg1	CMC					276:278	CMC	276:278	CMC	276:278	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
36565040	1	117	theme	carboxymethyl	252:264	arg1	chitosan					266:273	carboxymethyl chitosan	252:273	carboxymethyl chitosan (CMC)	252:279	AIM To compare the odontogenic differentiation potential of a composite scaffold (CSHA) comprising of nano-hydroxyapatite (nHAp) and carboxymethyl chitosan (CMC) with Biodentine on human dental pulp stem cells (hDPSCs).					
37086768	5	0	from	45 °C	838:842	arg1	capacity					810:817	a maximum biosorption capacity	788:817	a maximum biosorption capacity of 0.671 mmol/g at 45 °C	788:842	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	7	1	dep	particles	977:985	arg1	reuse					987:991	reuse	987:991	reuse	987:991	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	7	1	dep	particles	977:985	arg1	recovery					1002:1009	Ce3+ recovery	997:1009	Ce3+ recovery	997:1009	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	7	1	dep	particles	977:985	arg1	particles					977:985	The particles reuse and Ce3+ recovery	973:1009	The particles reuse and Ce3+ recovery	973:1009	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	1	2	theme	secondary	255:263	arg1	sources					265:271	secondary sources	255:271	secondary sources	255:271	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	0	3	theme	Kinetics	99:106	arg1	studies					147:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	1	4	from	perspective	332:342	arg1	strategy					288:295	a promising strategy	276:295	a promising strategy	276:295	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	1	5	theme	essential	169:177	arg1	element					179:185	an essential element	166:185	an essential element for several applications in industry	166:222	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	1	5	theme	essential	169:177	arg1	Cerium					156:161	Cerium	156:161	Cerium	156:161	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	8	6	theme	textural	1222:1229	arg1	properties					1231:1240	textural properties	1222:1240	textural properties	1222:1240	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	7	7	theme	0.1 mol/L	1031:1039	arg1	HCl					1041:1043	0.1 mol/L HCl	1031:1043	0.1 mol/L HCl	1031:1043	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	0	8	theme	equilibrium	109:119	arg1	studies					147:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	7	9	theme	Ce3+	997:1000	arg1	recovery					1002:1009	Ce3+ recovery	997:1009	Ce3+ recovery	997:1009	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	7	9	theme	Ce3+	997:1000	arg1	particles					977:985	The particles reuse and Ce3+ recovery	973:1009	The particles reuse and Ce3+ recovery	973:1009	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	5	10	theme	equilibrium	766:776	arg1	data					778:781	the equilibrium data	762:781	the equilibrium data	762:781	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	3	11	theme	ionic	555:559	arg1	imprinting					561:570	ionic imprinting	555:570	ionic imprinting	555:570	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	0	12	theme	thermodynamic	122:134	arg1	studies					147:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	5	13	theme	biosorption	798:808	arg1	capacity					810:817	a maximum biosorption capacity	788:817	a maximum biosorption capacity of 0.671 mmol/g at 45 °C	788:842	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	2	14	theme	effective	393:401	arg1	biosorption					363:373	biosorption	363:373	biosorption	363:373	For this purpose, biosorption is a low-cost and effective alternative.					
37086768	2	14	theme	effective	393:401	arg1	alternative					403:413	a low-cost and effective alternative	378:413	a low-cost and effective alternative	378:413	For this purpose, biosorption is a low-cost and effective alternative.					
37086768	5	15	theme	maximum	790:796	arg1	capacity					810:817	a maximum biosorption capacity	788:817	a maximum biosorption capacity of 0.671 mmol/g at 45 °C	788:842	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	4	16	theme	kinetic	582:588	arg1	assays					590:595	the kinetic assays	578:595	the kinetic assays	578:595	From the kinetic assays, it was verified that the uptake of Ce3+ followed the pseudo-second-order model and was mainly controlled by external diffusion.					
37086768	1	17	theme	several	191:197	arg1	applications					199:210	several applications	191:210	several applications in industry	191:222	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	0	18	theme	Cerium	0:5	arg1	biosorption					7:17	Cerium biosorption	0:17	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting	0:96	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	1	19	theme	promising	278:286	arg1	strategy					288:295	a promising strategy	276:295	a promising strategy	276:295	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	2	20	theme	low-cost	380:387	arg1	biosorption					363:373	biosorption	363:373	biosorption	363:373	For this purpose, biosorption is a low-cost and effective alternative.					
37086768	2	20	theme	low-cost	380:387	arg1	alternative					403:413	a low-cost and effective alternative	378:413	a low-cost and effective alternative	378:413	For this purpose, biosorption is a low-cost and effective alternative.					
37086768	0	21	theme	alginate/vermiculite-based	24:49	arg1	particles					51:59	alginate/vermiculite-based particles	24:59	alginate/vermiculite-based particles functionalized with ionic imprinting	24:96	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	0	22	theme	reuse	141:145	arg1	studies					147:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Kinetics, equilibrium, thermodynamic, and reuse studies	99:153	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	3	23	theme	aqueous	469:475	arg1	solutions					477:485	aqueous solutions	469:485	aqueous solutions	469:485	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	8	24	theme	thermal	1258:1264	arg1	resistance					1266:1275	thermal resistance	1258:1275	thermal resistance	1258:1275	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	5	25	theme	Langmuir	730:737	arg1	model					739:743	The Langmuir model	726:743	The Langmuir model	726:743	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	7	26	dep	HCl	1041:1043	arg1	solutions					1064:1072	solutions	1064:1072	solutions	1064:1072	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	resistance					1266:1275	thermal resistance	1258:1275	thermal resistance	1258:1275	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	groups					1306:1311	functional groups	1295:1311	functional groups of the biosorbent	1295:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	properties					1231:1240	textural properties	1222:1240	textural properties	1222:1240	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	composition					1278:1288	composition	1278:1288	composition	1278:1288	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	biosorbent					1320:1329	the biosorbent	1316:1329	the biosorbent	1316:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	crystallinity					1243:1255	crystallinity	1243:1255	crystallinity	1243:1255	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	27	theme	biosorbent	1320:1329	arg1	morphology					1210:1219	the morphology	1206:1219	the morphology	1206:1219	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	3	28	theme	present	420:426	arg1	work					428:431	The present work	416:431	The present work	416:431	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	8	29	theme	posted	1167:1172	arg1	biosorption					1179:1189	posted Ce3+ biosorption	1167:1189	posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent	1167:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	6	30	theme	quantities	894:903	arg1	evaluation					862:871	The evaluation	858:871	The evaluation of the thermodynamic quantities	858:903	The evaluation of the thermodynamic quantities revealed that the process occurs spontaneously and endothermically.					
37086768	3	31	theme	Ce3+	459:462	arg1	recovery					447:454	the recovery	443:454	the recovery of Ce3+ from aqueous solutions	443:485	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	1	32	theme	economic	305:312	arg1	perspective					332:342	an economic and environmental perspective	302:342	an economic and environmental perspective	302:342	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	7	33	theme	biosorption/desorption	1099:1120	arg1	cycles					1089:1094	up to four cycles	1078:1094	up to four cycles of biosorption/desorption	1078:1120	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	6	34	theme	thermodynamic	880:892	arg1	quantities					894:903	the thermodynamic quantities	876:903	the thermodynamic quantities	876:903	The evaluation of the thermodynamic quantities revealed that the process occurs spontaneously and endothermically.					
37086768	4	35	theme	pseudo-second-order	651:669	arg1	model					671:675	the pseudo-second-order model	647:675	the pseudo-second-order model	647:675	From the kinetic assays, it was verified that the uptake of Ce3+ followed the pseudo-second-order model and was mainly controlled by external diffusion.					
37086768	0	36	theme	ionic	81:85	arg1	imprinting					87:96	ionic imprinting	81:96	ionic imprinting	81:96	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
37086768	7	37	dep	four	1084:1087	arg1	to					1081:1082	to	1081:1082	to	1081:1082	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	1	38	dep	recovering	236:245	arg1	strategy					288:295	a promising strategy	276:295	a promising strategy	276:295	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	5	39	theme	0.671 mmol/g	822:833	arg1	capacity					810:817	a maximum biosorption capacity	788:817	a maximum biosorption capacity of 0.671 mmol/g at 45 °C	788:842	The Langmuir model better described the equilibrium data, and a maximum biosorption capacity of 0.671 mmol/g at 45 °C was attained.					
37086768	1	40	theme	environmental	318:330	arg1	perspective					332:342	an economic and environmental perspective	302:342	an economic and environmental perspective	302:342	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	7	41	theme	1.0 mol/L	1048:1056	arg1	CaCl2					1058:1062	1.0 mol/L CaCl2	1048:1062	1.0 mol/L CaCl2	1048:1062	The particles reuse and Ce3+ recovery were achieved using 0.1 mol/L HCl or 1.0 mol/L CaCl2 solutions for up to four cycles of biosorption/desorption.					
37086768	3	42	from	solutions	477:485	arg1	recovery					447:454	the recovery	443:454	the recovery of Ce3+ from aqueous solutions	443:485	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	8	43	theme	Ce3+	1174:1177	arg1	biosorption					1179:1189	posted Ce3+ biosorption	1167:1189	posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent	1167:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	3	44	theme	alginate/vermiculite-based	493:518	arg1	particles					520:528	alginate/vermiculite-based particles	493:528	alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting	493:570	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	3	44	theme	alginate/vermiculite-based	493:518	arg1	ALEV					531:534	ALEV	531:534	ALEV	531:534	The present work evaluated the recovery of Ce3+ from aqueous solutions using alginate/vermiculite-based particles (ALEV) functionalized by ionic imprinting.					
37086768	1	45	from	applications	199:210	arg1	industry					215:222	industry	215:222	industry	215:222	Cerium is an essential element for several applications in industry, therefore, recovering it from secondary sources is a promising strategy from an economic and environmental perspective.					
37086768	4	46	theme	external	706:713	arg1	diffusion					715:723	external diffusion	706:723	external diffusion	706:723	From the kinetic assays, it was verified that the uptake of Ce3+ followed the pseudo-second-order model and was mainly controlled by external diffusion.					
37086768	8	47	theme	functional	1295:1304	arg1	groups					1306:1311	functional groups	1295:1311	functional groups of the biosorbent	1295:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	8	47	theme	functional	1295:1304	arg1	biosorbent					1320:1329	the biosorbent	1316:1329	the biosorbent	1316:1329	The biosorbent was characterized before and posted Ce3+ biosorption to investigate the morphology, textural properties, crystallinity, thermal resistance, composition, and functional groups of the biosorbent.					
37086768	4	48	theme	Ce3+	633:636	arg1	uptake					623:628	the uptake	619:628	the uptake of Ce3+	619:636	From the kinetic assays, it was verified that the uptake of Ce3+ followed the pseudo-second-order model and was mainly controlled by external diffusion.					
37086768	0	49	dep	studies	147:153	arg1	biosorption					7:17	Cerium biosorption	0:17	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting	0:96	Cerium biosorption onto alginate/vermiculite-based particles functionalized with ionic imprinting: Kinetics, equilibrium, thermodynamic, and reuse studies.					
35454093	11	0	theme	mg	1315:1316	arg1	N-deficiency					1297:1308	N-deficiency	1297:1308	N-deficiency (213 mg g-1)	1297:1321	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	11	0	theme	mg	1315:1316	arg1	g-1					1318:1320	213 mg g-1	1311:1320	213 mg g-1	1311:1320	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	10	1	theme	fluorescence	1186:1197	arg1	crosstalk					1208:1216	fluorescence emission crosstalk	1186:1216	fluorescence emission crosstalk with phycocyanin	1186:1233	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	14	2	theme	PHB	1546:1548	arg1	formation					1550:1558	PHB formation	1546:1558	PHB formation	1546:1558	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	9	3	theme	fluorescence-based	1025:1042	arg1	monitoring					1044:1053	fluorescence-based monitoring	1025:1053	fluorescence-based monitoring	1025:1053	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	7	4	theme	three-stage	662:672	arg1	process					686:692	a three-stage cultivation process	660:692	a three-stage cultivation process	660:692	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	7	5	theme	cultivation	674:684	arg1	process					686:692	a three-stage cultivation process	660:692	a three-stage cultivation process	660:692	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	4	6	theme	PHB	497:499	arg1	synthesis					484:492	the high-yield synthesis	469:492	the high-yield synthesis of PHB	469:499	So far, only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB have been reported.					
35454093	11	7	theme	highest	1240:1246	arg1	yields					1252:1257	The highest PHB yields	1236:1257	The highest PHB yields	1236:1257	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	12	8	theme	glycogen	1328:1335	arg1	pool					1337:1340	The glycogen pool	1324:1340	The glycogen pool	1324:1340	The glycogen pool was reduced in all cultures during mixotrophy, while lipid composition was not affected.					
35454093	14	9	theme	storage	1525:1531	arg1	capacity					1533:1540	the high carbon storage capacity	1509:1540	the high carbon storage capacity	1509:1540	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	10	10	theme	red	1167:1169	arg1	Nile					1162:1165	Nile red	1162:1169	Nile red	1162:1169	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	2	11	theme	promising	153:161	arg1	source					163:168	a promising source	151:168	a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB)	151:266	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	2	11	theme	promising	153:161	arg1	Cyanobacteria					133:145	Cyanobacteria	133:145	Cyanobacteria	133:145	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	11	12	theme	PHB	1248:1250	arg1	yields					1252:1257	The highest PHB yields	1236:1257	The highest PHB yields	1236:1257	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	9	13	dep	dyes	981:984	arg1	dyes					981:984	the fluorescent dyes	965:984	the fluorescent dyes LipidGreen2 and Nile red	965:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	13	dep	dyes	981:984	arg1	Nile					1002:1005	Nile red	1002:1009	Nile red	1002:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	13	dep	dyes	981:984	arg1	LipidGreen2					986:996	LipidGreen2	986:996	LipidGreen2	986:996	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	14	theme	PHB	1080:1082	arg1	monitoring					1044:1053	fluorescence-based monitoring	1025:1053	fluorescence-based monitoring	1025:1053	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	14	theme	PHB	1080:1082	arg1	visualization					1063:1075	the visualization	1059:1075	the visualization of PHB	1059:1082	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	7	15	theme	mixotrophic	801:811	arg1	stage					824:828	a subsequent mixotrophic deficiency stage	788:828	a subsequent mixotrophic deficiency stage	788:828	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	10	16	theme	Nile	1162:1165	arg1	application					1147:1157	the application	1143:1157	the application of Nile red	1143:1169	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	4	17	theme	suitable	456:463	arg1	species					448:454	cyanobacterial species	433:454	cyanobacterial species suitable for the high-yield synthesis of PHB	433:499	So far, only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB have been reported.					
35454093	5	18	theme	elemental	575:583	arg1	composition					585:595	elemental composition	575:595	elemental composition	575:595	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	1	19	theme	Poly	57:60	arg1	Production					81:90	Poly(3-hydroxybutyrate) Production	57:90	Poly(3-hydroxybutyrate) Production	57:90	NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions.					
35454093	7	20	theme	deficiency	813:822	arg1	stage					824:828	a subsequent mixotrophic deficiency stage	788:828	a subsequent mixotrophic deficiency stage	788:828	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	4	21	theme	high-yield	473:482	arg1	synthesis					484:492	the high-yield synthesis	469:492	the high-yield synthesis of PHB	469:499	So far, only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB have been reported.					
35454093	0	22	theme	Leptolyngbya	0:11	arg1	sp					13:14	Leptolyngbya sp	0:14	Leptolyngbya sp.	0:15	Leptolyngbya sp.					
35454093	14	23	theme	carbon	1518:1523	arg1	capacity					1533:1540	the high carbon storage capacity	1509:1540	the high carbon storage capacity	1509:1540	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	5	24	theme	Leptolyngbya	600:611	arg1	sp					613:614	Leptolyngbya sp	600:614	Leptolyngbya sp	600:614	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	5	25	theme	PHB	547:549	arg1	formation					551:559	the PHB formation	543:559	the PHB formation	543:559	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	13	26	theme	mg	1493:1494	arg1	N-deficiency					1475:1486	N-deficiency	1475:1486	N-deficiency (217 mg g-1)	1475:1499	The highest glycogen yield was formed under N-deficiency (217 mg g-1).					
35454093	13	26	theme	mg	1493:1494	arg1	g-1					1496:1498	217 mg g-1	1489:1498	217 mg g-1	1489:1498	The highest glycogen yield was formed under N-deficiency (217 mg g-1).					
35454093	7	27	theme	subsequent	790:799	arg1	stage					824:828	a subsequent mixotrophic deficiency stage	788:828	a subsequent mixotrophic deficiency stage	788:828	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	3	28	theme	heterotrophic	370:382	arg1	systems					398:404	heterotrophic PHB-producing systems	370:404	heterotrophic PHB-producing systems	370:404	The auto-phototrophic biomass formation is based on light and CO2, which is an advantage compared to heterotrophic PHB-producing systems.					
35454093	5	29	theme	sp	613:614	arg1	formation					551:559	the PHB formation	543:559	the PHB formation	543:559	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	5	29	theme	sp	613:614	arg1	composition					585:595	elemental composition	575:595	elemental composition	575:595	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	5	29	theme	sp	613:614	arg1	biomass					562:568	biomass	562:568	biomass	562:568	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	13	30	theme	highest	1435:1441	arg1	yield					1452:1456	The highest glycogen yield	1431:1456	The highest glycogen yield	1431:1456	The highest glycogen yield was formed under N-deficiency (217 mg g-1).					
35454093	11	31	theme	325	1281:1283	arg1	mg					1285:1286	mg	1285:1286	mg	1285:1286	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	7	32	theme	NP-depleted	752:762	arg1	stage					777:781	NP-depleted phototrophic stage	752:781	NP-depleted phototrophic stage	752:781	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	15	33	theme	promising	1596:1604	arg1	NIVA-CYA					1578:1585	NIVA-CYA 255	1578:1589	NIVA-CYA 255	1578:1589	NIVA-CYA 255 is a promising candidate for PHB production.					
35454093	15	33	theme	promising	1596:1604	arg1	candidate					1606:1614	a promising candidate	1594:1614	a promising candidate for PHB production	1594:1633	NIVA-CYA 255 is a promising candidate for PHB production.					
35454093	3	34	theme	auto-phototrophic	273:289	arg1	formation					299:307	The auto-phototrophic biomass formation	269:307	The auto-phototrophic biomass formation	269:307	The auto-phototrophic biomass formation is based on light and CO2, which is an advantage compared to heterotrophic PHB-producing systems.					
35454093	2	35	theme	sustainable	178:188	arg1	production					190:199	the sustainable production	174:199	the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB)	174:266	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	7	36	theme	phototrophic	764:775	arg1	stage					777:781	NP-depleted phototrophic stage	752:781	NP-depleted phototrophic stage	752:781	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	9	37	used	used	1016:1019	arg2	dyes					981:984	the fluorescent dyes	965:984	the fluorescent dyes LipidGreen2 and Nile red	965:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	37	used	used	1016:1019	arg2	Nile					1002:1005	Nile red	1002:1009	Nile red	1002:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	37	used	used	1016:1019	arg2	LipidGreen2					986:996	LipidGreen2	986:996	LipidGreen2	986:996	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	10	38	with	crosstalk	1208:1216	arg1	phycocyanin					1223:1233	phycocyanin	1223:1233	phycocyanin	1223:1233	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	14	39	dep	sp	1574:1575	arg1	capacity					1533:1540	the high carbon storage capacity	1509:1540	the high carbon storage capacity	1509:1540	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	14	39	dep	sp	1574:1575	arg1	formation					1550:1558	PHB formation	1546:1558	PHB formation	1546:1558	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	16	40	theme	Further	1636:1642	arg1	work					1644:1647	Further work	1636:1647	Further work	1636:1647	Further work will focus on upscaling to a technical scale and monitoring the formation by LipidGreen2-based fluorometry.					
35454093	4	41	theme	species	448:454	arg1	handful					422:428	only a handful	415:428	only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB	415:499	So far, only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB have been reported.					
35454093	8	42	theme	extracted	880:888	arg1	PHB					905:907	The extracted cyanobacterial PHB	876:907	The extracted cyanobacterial PHB	876:907	The extracted cyanobacterial PHB was confirmed by FTIR- and GC-MS analyses.					
35454093	3	43	theme	PHB-producing	384:396	arg1	systems					398:404	heterotrophic PHB-producing systems	370:404	heterotrophic PHB-producing systems	370:404	The auto-phototrophic biomass formation is based on light and CO2, which is an advantage compared to heterotrophic PHB-producing systems.					
35454093	16	44	theme	technical	1678:1686	arg1	scale					1688:1692	a technical scale	1676:1692	a technical scale	1676:1692	Further work will focus on upscaling to a technical scale and monitoring the formation by LipidGreen2-based fluorometry.					
35454093	4	45	theme	cyanobacterial	433:446	arg1	species					448:454	cyanobacterial species	433:454	cyanobacterial species suitable for the high-yield synthesis of PHB	433:499	So far, only a handful of cyanobacterial species suitable for the high-yield synthesis of PHB have been reported.					
35454093	5	46	theme	present	528:534	arg1	study					536:540	the present study	524:540	the present study	524:540	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
35454093	1	47	theme	Mixotrophic	98:108	arg1	Conditions					121:130	Mixotrophic Deficiency Conditions	98:130	Mixotrophic Deficiency Conditions	98:130	NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions.					
35454093	9	48	theme	fluorescent	969:979	arg1	dyes					981:984	the fluorescent dyes	965:984	the fluorescent dyes LipidGreen2 and Nile red	965:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	48	theme	fluorescent	969:979	arg1	Nile					1002:1005	Nile red	1002:1009	Nile red	1002:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	48	theme	fluorescent	969:979	arg1	LipidGreen2					986:996	LipidGreen2	986:996	LipidGreen2	986:996	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	10	49	theme	PHB	1117:1119	arg1	quantification					1121:1134	PHB quantification	1117:1134	PHB quantification	1117:1134	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	2	50	theme	bioplastics	218:228	arg1	production					190:199	the sustainable production	174:199	the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB)	174:266	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	12	51	theme	lipid	1395:1399	arg1	composition					1401:1411	lipid composition	1395:1411	lipid composition	1395:1411	The glycogen pool was reduced in all cultures during mixotrophy, while lipid composition was not affected.					
35454093	1	52	theme	Deficiency	110:119	arg1	Conditions					121:130	Mixotrophic Deficiency Conditions	98:130	Mixotrophic Deficiency Conditions	98:130	NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions.					
35454093	8	53	dep	FTIR-	926:930	arg1	analyses					942:949	analyses	942:949	analyses	942:949	The extracted cyanobacterial PHB was confirmed by FTIR- and GC-MS analyses.					
35454093	3	54	theme	biomass	291:297	arg1	formation					299:307	The auto-phototrophic biomass formation	269:307	The auto-phototrophic biomass formation	269:307	The auto-phototrophic biomass formation is based on light and CO2, which is an advantage compared to heterotrophic PHB-producing systems.					
35454093	2	55	theme	biodegradable	204:216	arg1	poly					238:241	poly	238:241	poly(3-hydroxybutyrate) (PHB)	238:266	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	2	55	theme	biodegradable	204:216	arg1	bioplastics					218:228	biodegradable bioplastics	204:228	biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB)	204:266	Cyanobacteria are a promising source for the sustainable production of biodegradable bioplastics such as poly(3-hydroxybutyrate) (PHB).					
35454093	13	56	theme	glycogen	1443:1450	arg1	yield					1452:1456	The highest glycogen yield	1431:1456	The highest glycogen yield	1431:1456	The highest glycogen yield was formed under N-deficiency (217 mg g-1).					
35454093	8	57	theme	cyanobacterial	890:903	arg1	PHB					905:907	The extracted cyanobacterial PHB	876:907	The extracted cyanobacterial PHB	876:907	The extracted cyanobacterial PHB was confirmed by FTIR- and GC-MS analyses.					
35454093	16	58	theme	LipidGreen2-based	1726:1742	arg1	fluorometry					1744:1754	LipidGreen2-based fluorometry	1726:1754	LipidGreen2-based fluorometry	1726:1754	Further work will focus on upscaling to a technical scale and monitoring the formation by LipidGreen2-based fluorometry.					
35454093	10	59	theme	emission	1199:1206	arg1	crosstalk					1208:1216	fluorescence emission crosstalk	1186:1216	fluorescence emission crosstalk with phycocyanin	1186:1233	LipidGreen2 was well suited for PHB quantification, while the application of Nile red was limited by fluorescence emission crosstalk with phycocyanin.					
35454093	7	60	theme	growth	723:728	arg1	stage					730:734	a growth stage	721:734	a growth stage	721:734	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	14	61	theme	high	1513:1516	arg1	capacity					1533:1540	the high carbon storage capacity	1509:1540	the high carbon storage capacity	1509:1540	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	11	62	located	detected	1264:1271	arg1	g-1					1288:1290	325 mg g-1	1281:1290	325 mg g-1	1281:1290	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	11	62	located	detected	1264:1271	arg1	N-deficiency					1297:1308	N-deficiency	1297:1308	N-deficiency (213 mg g-1)	1297:1321	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	11	62	located	detected	1264:1271	arg1	NP-					1276:1278	NP-	1276:1278	NP- (325 mg g-1)	1276:1291	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	11	62	located	detected	1264:1271	arg1	g-1					1318:1320	213 mg g-1	1311:1320	213 mg g-1	1311:1320	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	11	62	located	detected	1264:1271	arg2	yields					1252:1257	The highest PHB yields	1236:1257	The highest PHB yields	1236:1257	The highest PHB yields were detected in NP- (325 mg g-1) and N-deficiency (213 mg g-1).					
35454093	7	63	theme	sodium	844:849	arg1	supplementation					859:873	sodium acetate supplementation	844:873	sodium acetate supplementation	844:873	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	15	64	theme	PHB	1620:1622	arg1	production					1624:1633	PHB production	1620:1633	PHB production	1620:1633	NIVA-CYA 255 is a promising candidate for PHB production.					
35454093	9	65	theme	red	1007:1009	arg1	dyes					981:984	the fluorescent dyes	965:984	the fluorescent dyes LipidGreen2 and Nile red	965:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	9	65	theme	red	1007:1009	arg1	Nile					1002:1005	Nile red	1002:1009	Nile red	1002:1009	Furthermore, the fluorescent dyes LipidGreen2 and Nile red were used for fluorescence-based monitoring and the visualization of PHB.					
35454093	7	66	theme	acetate	851:857	arg1	supplementation					859:873	sodium acetate supplementation	844:873	sodium acetate supplementation	844:873	Therefore, a three-stage cultivation process was applied, consisting of a growth stage; an N-, P-, and NP-depleted phototrophic stage; and a subsequent mixotrophic deficiency stage, initiated by sodium acetate supplementation.					
35454093	14	67	theme	Leptolyngbya	1561:1572	arg1	sp					1574:1575	Leptolyngbya sp	1561:1575	Leptolyngbya sp	1561:1575	Due to the high carbon storage capacity and PHB formation, Leptolyngbya sp.					
35454093	1	68	theme	Promising	33:41	arg1	Candidate					43:51	a Promising Candidate	31:51	a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions	31:130	NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions.					
35454093	1	68	theme	Promising	33:41	arg1	NIVA-CYA					17:24	NIVA-CYA	17:24	NIVA-CYA	17:24	NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions.					
35454093	5	69	dep	formation	551:559	arg1	study					536:540	the present study	524:540	the present study	524:540	In the present study, the PHB formation, biomass, and elemental composition of Leptolyngbya sp.					
37384658	3	0	theme	chemical	497:504	arg1	composition					506:516	the chemical composition	493:516	the chemical composition of sawdust	493:527	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	1	1	theme	mushrooms	237:245	arg1	profile					219:225	the nutritional profile	203:225	the nutritional profile of oyster mushrooms (Pleurotus ostreatus)	203:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	2	2	with	mushroom	413:420	arg1	preferences					443:453	desired dietary preferences	427:453	desired dietary preferences	427:453	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
37384658	10	3	theme	low	1576:1578	arg1	pH					1580:1581	low pH	1576:1581	low pH (slightly acidic to slightly basic)	1576:1617	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	1	4	theme	Pleurotus	248:256	arg1	mushrooms					237:245	oyster mushrooms	230:245	oyster mushrooms (Pleurotus ostreatus)	230:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	1	4	theme	Pleurotus	248:256	arg1	ostreatus					258:266	Pleurotus ostreatus	248:266	Pleurotus ostreatus	248:266	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	3	5	from	influence	480:488	arg1	macronutrients					536:549	macronutrients	536:549	macronutrients	536:549	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	3	5	from	influence	480:488	arg1	content					559:565	ash content	555:565	ash content	555:565	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	0	6	from	composition	95:105	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	6	from	composition	95:105	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	1	7	theme	chemical	168:175	arg1	composition					177:187	chemical composition	168:187	chemical composition of sawdust	168:198	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	3	8	theme	ash	555:557	arg1	content					559:565	ash content	555:565	ash content	555:565	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	0	9	theme	oyster	116:121	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	9	theme	oyster	116:121	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	3	10	theme	mushrooms	587:595	arg1	macronutrients					536:549	macronutrients	536:549	macronutrients	536:549	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	3	10	theme	mushrooms	587:595	arg1	content					559:565	ash content	555:565	ash content	555:565	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	4	11	theme	C-N	705:707	arg1	ratio					709:713	the C-N ratio	701:713	the C-N ratio	701:713	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	3	12	theme	pearl	574:578	arg1	mushrooms					587:595	the pearl oyster mushrooms	570:595	the pearl oyster mushrooms	570:595	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	8	13	theme	oyster	1308:1313	arg1	mushrooms					1315:1323	oyster mushrooms	1308:1323	oyster mushrooms	1308:1323	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	5	14	theme	ash	885:887	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	10	15	with	sawdust	1563:1569	arg1	pH					1580:1581	low pH	1576:1581	low pH (slightly acidic to slightly basic)	1576:1617	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	0	16	from	macronutrients	72:85	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	16	from	macronutrients	72:85	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	11	17	theme	crude	1719:1723	arg1	content					1731:1737	high crude fiber content	1714:1737	high crude fiber content	1714:1737	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	5	18	theme	crude	852:856	arg1	protein					858:864	crude protein	852:864	crude protein	852:864	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	10	19	dep	pH	1580:1581	arg1	acidic					1593:1598	acidic	1593:1598	acidic	1593:1598	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	0	20	from	Influence	0:8	arg1	levels					52:57	the levels	48:57	the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus)	48:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	10	21	theme	high	1536:1539	arg1	content					1549:1555	high protein content	1536:1555	high protein content	1536:1555	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	11	22	from	rich	1674:1677	arg1	hemicelluloses					1682:1695	hemicelluloses	1682:1695	hemicelluloses	1682:1695	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	7	23	dep	efficiency	1136:1145	arg1	%					1153:1153	44-50%	1148:1153	biological efficiency: 44-50%	1125:1153	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	0	24	theme	macronutrients	72:85	arg1	levels					52:57	the levels	48:57	the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus)	48:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	9	25	theme	significant	1384:1394	arg1	effect					1396:1401	a significant effect	1382:1401	a significant effect (p<0.05)	1382:1410	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	9	25	theme	significant	1384:1394	arg1	p<0.05					1404:1409	p<0.05	1404:1409	p<0.05	1404:1409	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	3	26	dep	macronutrients	536:549	arg1	the					532:534	the	532:534	the	532:534	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	11	27	from	hemicelluloses	1682:1695	arg1	rich					1674:1677	rich	1674:1677	rich	1674:1677	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	11	28	theme	low	1702:1704	arg1	fat					1706:1708	low fat	1702:1708	low fat	1702:1708	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	0	29	theme	ash	91:93	arg1	composition					95:105	ash composition	91:105	ash composition	91:105	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	2	30	theme	dietary	435:441	arg1	preferences					443:453	desired dietary preferences	427:453	desired dietary preferences	427:453	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
37384658	7	31	from	kg	1080:1081	arg1	yield					1049:1053	The yield	1045:1053	The yield of the mushroom (on 0.05 kg of sawdust)	1045:1093	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	11	32	theme	high	1714:1717	arg1	content					1731:1737	high crude fiber content	1714:1737	high crude fiber content	1714:1737	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	8	33	theme	sawdust	1233:1239	arg1	pH					1223:1224	pH	1223:1224	pH of the sawdust	1223:1239	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	10	34	theme	mushroom	1497:1504	arg1	producers					1506:1514	the mushroom producers	1493:1514	the mushroom producers	1493:1514	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	5	35	theme	oyster	904:909	arg1	mushroom					911:918	the oyster mushroom	900:918	the oyster mushroom cultivated on the sawdust	900:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	7	36	theme	carbohydrates	1169:1181	arg1	%					1220:1220	56.28%	1215:1220	56.28%	1215:1220	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	7	36	theme	carbohydrates	1169:1181	arg1	constituent					1183:1193	the average carbohydrates constituent	1157:1193	the average carbohydrates constituent in the mushroom	1157:1209	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	4	37	theme	wood	796:799	arg1	species					801:807	tropical wood species	787:807	tropical wood species	787:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	7	38	theme	mushroom	1062:1069	arg1	yield					1049:1053	The yield	1045:1053	The yield of the mushroom (on 0.05 kg of sawdust)	1045:1093	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	0	39	theme	content	26:32	arg1	Influence					0:8	Influence	0:8	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).	0:153	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	9	40	contain	had	1378:1380	arg1	hemicelluloses					1358:1371	The hemicelluloses	1354:1371	The hemicelluloses	1354:1371	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	9	40	contain	had	1378:1380	arg2	p<0.05					1404:1409	p<0.05	1404:1409	p<0.05	1404:1409	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	9	40	contain	had	1378:1380	arg2	effect					1396:1401	a significant effect	1382:1401	a significant effect (p<0.05)	1382:1410	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	0	41	theme	sawdust	37:43	arg1	content					26:32	the chemical content	13:32	the chemical content of sawdust	13:43	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	1	42	theme	significant	288:298	arg1	attention					309:317	significant research attention	288:317	significant research attention	288:317	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	4	43	theme	mixed	768:772	arg1	sawdust					774:780	mixed sawdust	768:780	mixed sawdust	768:780	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	7	44	from	constituent	1183:1193	arg1	mushroom					1202:1209	the mushroom	1198:1209	the mushroom	1198:1209	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	10	45	dep	acidic	1593:1598	arg1	basic					1612:1616	basic	1612:1616	basic	1612:1616	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	10	45	dep	acidic	1593:1598	arg1	to					1600:1601	to	1600:1601	to	1600:1601	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	3	46	theme	composition	506:516	arg1	influence					480:488	the influence	476:488	the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms	476:595	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	9	47	theme	fiber	1454:1458	arg1	minerals					1430:1437	the mushroom's minerals	1415:1437	the mushroom's minerals	1415:1437	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	9	47	theme	fiber	1454:1458	arg1	content					1460:1466	crude fiber content	1448:1466	crude fiber content	1448:1466	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	4	48	theme	American	602:609	arg1	Materials					632:640	The American Standard for Testing Materials	598:640	The American Standard for Testing Materials	598:640	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	10	49	theme	protein	1541:1547	arg1	content					1549:1555	high protein content	1536:1555	high protein content	1536:1555	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	1	50	theme	oyster	230:235	arg1	mushrooms					237:245	oyster mushrooms	230:245	oyster mushrooms (Pleurotus ostreatus)	230:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	1	50	theme	oyster	230:235	arg1	ostreatus					258:266	Pleurotus ostreatus	248:266	Pleurotus ostreatus	248:266	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	3	51	theme	sawdust	521:527	arg1	composition					506:516	the chemical composition	493:516	the chemical composition of sawdust	493:527	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	5	52	theme	fat	834:836	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	4	53	theme	other	646:650	arg1	protocols					668:676	other widely accepted protocols	646:676	other widely accepted protocols	646:676	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	4	54	theme	accepted	659:666	arg1	protocols					668:676	other widely accepted protocols	646:676	other widely accepted protocols	646:676	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	0	55	theme	Pearl	110:114	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	55	theme	Pearl	110:114	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	1	56	theme	composition	177:187	arg1	Influence					155:163	Influence	155:163	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus)	155:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	8	57	theme	ash	1293:1295	arg1	content					1297:1303	ash content	1293:1303	ash content of oyster mushrooms	1293:1323	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	57	theme	ash	1293:1295	arg1	protein					1262:1268	the crude protein	1252:1268	the crude protein	1252:1268	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	3	58	theme	oyster	580:585	arg1	mushrooms					587:595	the pearl oyster mushrooms	570:595	the pearl oyster mushrooms	570:595	This study assessed the influence of the chemical composition of sawdust on the macronutrients and ash content of the pearl oyster mushrooms.					
37384658	5	59	theme	fibre	845:849	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	1	60	theme	sawdust	192:198	arg1	composition					177:187	chemical composition	168:187	chemical composition of sawdust	168:198	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	0	61	from	levels	52:57	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	61	from	levels	52:57	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	62	theme	Pleurotus	133:141	arg1	mushroom					123:130	Pearl oyster mushroom	110:130	Pearl oyster mushroom (Pleurotus ostreatus)	110:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	0	62	theme	Pleurotus	133:141	arg1	ostreatus					143:151	Pleurotus ostreatus	133:151	Pleurotus ostreatus	133:151	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	4	63	from	species	801:807	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	5	64	theme	carbohydrate	867:878	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	7	65	from	mushroom	1062:1069	arg1	kg					1080:1081	0.05 kg	1075:1081	0.05 kg of sawdust	1075:1092	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	8	66	theme	mushrooms	1315:1323	arg1	content					1297:1303	ash content	1293:1303	ash content of oyster mushrooms	1293:1323	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	66	theme	mushrooms	1315:1323	arg1	p<0.05					1326:1331	p<0.05	1326:1331	p<0.05	1326:1331	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	66	theme	mushrooms	1315:1323	arg1	protein					1262:1268	the crude protein	1252:1268	the crude protein	1252:1268	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	66	theme	mushrooms	1315:1323	arg1	fat					1285:1287	fat	1285:1287	fat	1285:1287	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	10	67	from	sawdust	1563:1569	arg1	mushroom					1633:1640	the oyster mushroom	1622:1640	the oyster mushroom	1622:1640	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	4	68	theme	ratio	709:713	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	10	69	theme	oyster	1626:1631	arg1	mushroom					1633:1640	the oyster mushroom	1622:1640	the oyster mushroom	1622:1640	The study revealed that the mushroom producers would likely obtain high protein content using sawdust with low pH (slightly acidic to slightly basic) in the oyster mushroom.					
37384658	6	70	theme	largest	973:979	arg1	component					981:989	the largest component	969:989	the largest component of the sawdust (47.82%)	969:1013	Cellulose constituted the largest component of the sawdust (47.82%), followed by lignin (33.29%).					
37384658	7	71	from	yield	1049:1053	arg1	kg					1080:1081	0.05 kg	1075:1081	0.05 kg of sawdust	1075:1092	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	0	72	theme	important	62:70	arg1	macronutrients					72:85	important macronutrients	62:85	important macronutrients	62:85	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	11	73	theme	rich	1674:1677	arg1	substrates					1662:1671	substrates	1662:1671	substrates	1662:1671	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	1	74	from	Influence	155:163	arg1	profile					219:225	the nutritional profile	203:225	the nutritional profile of oyster mushrooms (Pleurotus ostreatus)	203:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	5	75	theme	protein	858:864	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	5	76	theme	mushroom	911:918	arg1	content					889:895	the fat, crude fibre, crude protein, carbohydrate, and ash content	830:895	the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust	830:944	The study evaluated the fat, crude fibre, crude protein, carbohydrate, and ash content of the oyster mushroom cultivated on the sawdust.					
37384658	4	77	theme	hemicellulose	728:740	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	0	78	theme	composition	95:105	arg1	levels					52:57	the levels	48:57	the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus)	48:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	11	79	contain	had	1698:1700	arg2	content					1731:1737	high crude fiber content	1714:1737	high crude fiber content	1714:1737	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	11	79	contain	had	1698:1700	arg1	Mushrooms					1643:1651	Mushrooms	1643:1651	Mushrooms grown on substrates, rich in hemicelluloses,	1643:1696	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	11	79	contain	had	1698:1700	arg2	fat					1706:1708	low fat	1702:1708	low fat	1702:1708	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	4	80	theme	cellulose	746:754	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	2	81	theme	specific	374:381	arg1	sawdust					383:389	specific sawdust	374:389	specific sawdust for the production of mushroom with desired dietary preferences	374:453	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
37384658	2	82	theme	desired	427:433	arg1	preferences					443:453	desired dietary preferences	427:453	desired dietary preferences	427:453	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
37384658	4	83	theme	pH	716:717	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	0	84	theme	chemical	17:24	arg1	content					26:32	the chemical content	13:32	the chemical content of sawdust	13:43	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	4	85	used	used	683:686	arg2	protocols					668:676	other widely accepted protocols	646:676	other widely accepted protocols	646:676	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	4	85	used	used	683:686	arg2	Materials					632:640	The American Standard for Testing Materials	598:640	The American Standard for Testing Materials	598:640	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	7	86	theme	average	1161:1167	arg1	%					1220:1220	56.28%	1215:1220	56.28%	1215:1220	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	7	86	theme	average	1161:1167	arg1	constituent					1183:1193	the average carbohydrates constituent	1157:1193	the average carbohydrates constituent in the mushroom	1157:1209	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	2	87	theme	mushroom	413:420	arg1	production					399:408	the production	395:408	the production of mushroom with desired dietary preferences	395:453	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
37384658	4	88	theme	lignin	720:725	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	11	89	theme	fiber	1725:1729	arg1	content					1731:1737	high crude fiber content	1714:1737	high crude fiber content	1714:1737	Mushrooms grown on substrates, rich in hemicelluloses, had low fat and high crude fiber content.					
37384658	6	90	theme	sawdust	998:1004	arg1	component					981:989	the largest component	969:989	the largest component of the sawdust (47.82%)	969:1013	Cellulose constituted the largest component of the sawdust (47.82%), followed by lignin (33.29%).					
37384658	7	91	dep	540.9	1116:1120	arg1	to					1113:1114	to	1113:1114	to	1113:1114	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	4	92	theme	tropical	787:794	arg1	species					801:807	tropical wood species	787:807	tropical wood species	787:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	7	93	theme	sawdust	1086:1092	arg1	kg					1080:1081	0.05 kg	1075:1081	0.05 kg of sawdust	1075:1092	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	8	94	theme	crude	1256:1260	arg1	content					1297:1303	ash content	1293:1303	ash content of oyster mushrooms	1293:1323	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	94	theme	crude	1256:1260	arg1	carbohydrate					1271:1282	carbohydrate	1271:1282	carbohydrate	1271:1282	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	94	theme	crude	1256:1260	arg1	protein					1262:1268	the crude protein	1252:1268	the crude protein	1252:1268	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	8	94	theme	crude	1256:1260	arg1	fat					1285:1287	fat	1285:1287	fat	1285:1287	pH of the sawdust influenced the crude protein, carbohydrate, fat and ash content of oyster mushrooms (p<0.05) most significantly.					
37384658	1	95	theme	research	300:307	arg1	attention					309:317	significant research attention	288:317	significant research attention	288:317	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	0	96	from	mushroom	123:130	arg1	levels					52:57	the levels	48:57	the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus)	48:152	Influence of the chemical content of sawdust on the levels of important macronutrients and ash composition in Pearl oyster mushroom (Pleurotus ostreatus).					
37384658	7	97	dep	ranged	1095:1100	arg1	efficiency					1136:1145	biological efficiency	1125:1145	biological efficiency: 44-50%	1125:1153	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	1	98	theme	nutritional	207:217	arg1	profile					219:225	the nutritional profile	203:225	the nutritional profile of oyster mushrooms (Pleurotus ostreatus)	203:267	Influence of chemical composition of sawdust on the nutritional profile of oyster mushrooms (Pleurotus ostreatus) has yet to receive significant research attention.					
37384658	9	99	theme	crude	1448:1452	arg1	minerals					1430:1437	the mushroom's minerals	1415:1437	the mushroom's minerals	1415:1437	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	9	99	theme	crude	1448:1452	arg1	content					1460:1466	crude fiber content	1448:1466	crude fiber content	1448:1466	The hemicelluloses also had a significant effect (p<0.05) on the mushroom's minerals, fat and crude fiber content.					
37384658	7	100	theme	biological	1125:1134	arg1	efficiency					1136:1145	biological efficiency	1125:1145	biological efficiency: 44-50%	1125:1153	The yield of the mushroom (on 0.05 kg of sawdust) ranged from 490.1 to 540.9 g (biological efficiency: 44-50%); the average carbohydrates constituent in the mushroom was 56.28%.					
37384658	4	101	theme	sawdust	774:780	arg1	contents					756:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents	701:763	the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species	701:807	The American Standard for Testing Materials and other widely accepted protocols were used to determine the C-N ratio, pH, lignin, hemicellulose and cellulose contents of mixed sawdust from tropical wood species.					
37384658	2	102	theme	mushroom	347:354	arg1	growers					356:362	mushroom growers	347:362	mushroom growers	347:362	This information will help mushroom growers to select specific sawdust for the production of mushroom with desired dietary preferences.					
35143802	0	0	theme	hydroxide/chitosan	79:96	arg1	composite					105:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	7	1	theme	maximum	1100:1106	arg1	806.4 mg/g					1132:1141	806.4 mg/g	1132:1141	806.4 mg/g	1132:1141	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	7	1	theme	maximum	1100:1106	arg1	capacity					1119:1126	The maximum adsorption capacity	1096:1126	The maximum adsorption capacity	1096:1126	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	9	2	from	results	1424:1430	arg1	evident					1405:1411	evident	1405:1411	evident	1405:1411	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	8	3	theme	EBT	1305:1307	arg1	adsorption					1309:1318	EBT adsorption	1305:1318	EBT adsorption	1305:1318	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	6	4	theme	Redlich	977:983	arg1	R2 > 0.98					1011:1019	R2 > 0.98	1011:1019	R2 > 0.98	1011:1019	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	6	4	theme	Redlich	977:983	arg1	models					1003:1008	Redlich Peterson isotherm models	977:1008	Redlich Peterson isotherm models (R2 > 0.98)	977:1020	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	0	5	theme	double	72:77	arg1	composite					105:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	7	6	theme	adsorption	1108:1117	arg1	806.4 mg/g					1132:1141	806.4 mg/g	1132:1141	806.4 mg/g	1132:1141	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	7	6	theme	adsorption	1108:1117	arg1	capacity					1119:1126	The maximum adsorption capacity	1096:1126	The maximum adsorption capacity	1096:1126	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	5	7	dep	showed	825:830	arg1	fitting					839:845	fitting	839:845	showed better fitting to the pseudo-second order model	825:878	The kinetic results showed better fitting to the pseudo-second order model, and equilibrium was achieved within 30 min.					
35143802	0	8	dep	Performance	116:126	arg1	evaluation					128:137	evaluation	128:137	evaluation	128:137	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	0	9	theme	hybrid	98:103	arg1	composite					105:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	0	10	from	water	44:48	arg1	removal					9:15	removal	9:15	removal of Eriochrome Black T from water	9:48	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	9	11	theme	efficient	1505:1513	arg1	bio-adsorbent					1515:1527	an efficient bio-adsorbent	1502:1527	an efficient bio-adsorbent to effectively purify dye-contaminated water streams	1502:1580	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	1	12	theme	layered	255:261	arg1	CuFe					281:284	CuFe	281:284	CuFe	281:284	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	1	12	theme	layered	255:261	arg1	hydroxide					270:278	layered double hydroxide	255:278	layered double hydroxide (CuFe)	255:285	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	7	13	theme	pristine	1166:1173	arg1	476.19 mg/g					1183:1193	476.19 mg/g	1183:1193	476.19 mg/g	1183:1193	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	7	13	theme	pristine	1166:1173	arg1	B-CuFe					1175:1180	pristine B-CuFe	1166:1180	pristine B-CuFe (476.19 mg/g)	1166:1194	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	5	14	theme	kinetic	809:815	arg1	results					817:823	The kinetic results	805:823	The kinetic results	805:823	The kinetic results showed better fitting to the pseudo-second order model, and equilibrium was achieved within 30 min.					
35143802	2	15	theme	resultant	393:401	arg1	composite					403:411	The resultant composite	389:411	The resultant composite	389:411	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	4	16	dep	functionalities	704:718	arg1	-C-O					726:729	-C-O	726:729	-C-O	726:729	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	16	dep	functionalities	704:718	arg1	MMO					747:749	MMO	747:749	MMO	747:749	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	16	dep	functionalities	704:718	arg1	-OH					732:734	-OH	732:734	-OH	732:734	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	16	dep	functionalities	704:718	arg1	functionalities					704:718	abundant surface functionalities	687:718	abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO)	687:750	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	16	dep	functionalities	704:718	arg1	-CO					721:723	-CO	721:723	-CO	721:723	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	16	dep	functionalities	704:718	arg1	-NO3					737:740	-NO3	737:740	-NO3	737:740	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	6	17	theme	EBT	1038:1040	arg1	removal					1042:1048	the EBT removal	1034:1048	the EBT removal	1034:1048	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	2	18	theme	black	463:467	arg1	EBT					472:474	EBT	472:474	EBT	472:474	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	2	18	theme	black	463:467	arg1	T					469:469	Eriochrome black T	452:469	Eriochrome black T (EBT)	452:475	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	8	19	dep	analysis	1241:1248	arg1	XPS					1260:1262	XPS	1260:1262	XPS	1260:1262	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	8	19	dep	analysis	1241:1248	arg1	FTIR					1251:1254	FTIR	1251:1254	FTIR	1251:1254	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	1	20	theme	research	188:195	arg1	work					197:200	this research work	183:200	this research work	183:200	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	2	21	theme	adsorptive	430:439	arg1	removal					441:447	adsorptive removal	430:447	adsorptive removal of Eriochrome black T (EBT) from water	430:486	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	2	22	theme	T	469:469	arg1	removal					441:447	adsorptive removal	430:447	adsorptive removal of Eriochrome black T (EBT) from water	430:486	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	3	23	contain	containing	551:560	arg2	CS					570:571	10 wt % CS	562:571	10 wt % CS	562:571	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	3	23	contain	containing	551:560	arg1	B-CuFe-CS					541:549	the B-CuFe-CS	537:549	the B-CuFe-CS containing 10 wt % CS	537:571	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	3	24	theme	10 wt	562:566	arg1	CS					570:571	10 wt % CS	562:571	10 wt % CS	562:571	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	4	25	theme	abundant	687:694	arg1	-C-O					726:729	-C-O	726:729	-C-O	726:729	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	25	theme	abundant	687:694	arg1	MMO					747:749	MMO	747:749	MMO	747:749	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	25	theme	abundant	687:694	arg1	-OH					732:734	-OH	732:734	-OH	732:734	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	25	theme	abundant	687:694	arg1	functionalities					704:718	abundant surface functionalities	687:718	abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO)	687:750	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	25	theme	abundant	687:694	arg1	-CO					721:723	-CO	721:723	-CO	721:723	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	25	theme	abundant	687:694	arg1	-NO3					737:740	-NO3	737:740	-NO3	737:740	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	1	26	theme	double	263:268	arg1	CuFe					281:284	CuFe	281:284	CuFe	281:284	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	1	26	theme	double	263:268	arg1	hydroxide					270:278	layered double hydroxide	255:278	layered double hydroxide (CuFe)	255:285	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	3	27	theme	%	568:568	arg1	CS					570:571	10 wt % CS	562:571	10 wt % CS	562:571	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	9	28	theme	coupling	1437:1444	arg1	B-CuFe					1446:1451	coupling B-CuFe	1437:1451	coupling B-CuFe composite with bio-filler (chitosan)	1437:1488	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	0	29	theme	Eriochrome	20:29	arg1	T					37:37	Eriochrome Black T	20:37	Eriochrome Black T	20:37	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	9	30	dep	composite	1453:1461	arg1	with					1463:1466	with	1463:1466	with	1463:1466	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	8	31	theme	chemical	1357:1364	arg1	interactions					1385:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	8	32	theme	electrostatic	1342:1354	arg1	interactions					1385:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	3	33	with	structure	599:607	arg1	characteristics					651:665	better crystallographic and textural characteristics	614:665	better crystallographic and textural characteristics	614:665	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	1	34	theme	novel	205:209	arg1	composite					218:226	a novel hybrid composite	203:226	a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS)	203:315	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	0	35	theme	T	37:37	arg1	removal					9:15	removal	9:15	removal of Eriochrome Black T from water	9:48	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	9	36	theme	water	1568:1572	arg1	streams					1574:1580	dye-contaminated water streams	1551:1580	dye-contaminated water streams	1551:1580	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	1	37	theme	ultrasonication-assisted	339:362	arg1	method					381:386	an ultrasonication-assisted co-precipitation method	336:386	an ultrasonication-assisted co-precipitation method	336:386	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	8	38	theme	anion-exchange	1370:1383	arg1	interactions					1385:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	electrostatic, chemical and anion-exchange interactions	1342:1396	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	1	39	theme	hybrid	211:216	arg1	composite					218:226	a novel hybrid composite	203:226	a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS)	203:315	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	0	40	theme	Black	31:35	arg1	T					37:37	Eriochrome Black T	20:37	Eriochrome Black T	20:37	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	6	41	theme	Equilibrium	925:935	arg1	data					937:940	Equilibrium data	925:940	Equilibrium data	925:940	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	2	42	theme	Eriochrome	452:461	arg1	EBT					472:474	EBT	472:474	EBT	472:474	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	2	42	theme	Eriochrome	452:461	arg1	T					469:469	Eriochrome black T	452:469	Eriochrome black T (EBT)	452:475	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	1	43	theme	co-precipitation	364:379	arg1	method					381:386	an ultrasonication-assisted co-precipitation method	336:386	an ultrasonication-assisted co-precipitation method	336:386	In this research work, a novel hybrid composite consisting of biochar (B), layered double hydroxide (CuFe) and chitosan (CS) (B-CuFe-CS) was produced using an ultrasonication-assisted co-precipitation method.					
35143802	3	44	theme	heterogeneous	585:597	arg1	structure					599:607	a heterogeneous structure	583:607	a heterogeneous structure with better crystallographic and textural characteristics	583:665	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	5	45	theme	pseudo-second	854:866	arg1	model					874:878	the pseudo-second order model	850:878	the pseudo-second order model	850:878	The kinetic results showed better fitting to the pseudo-second order model, and equilibrium was achieved within 30 min.					
35143802	7	46	theme	many	1200:1203	arg1	adsorbents					1211:1220	many other adsorbents	1200:1220	many other adsorbents	1200:1220	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	3	47	theme	textural	642:649	arg1	characteristics					651:665	better crystallographic and textural characteristics	614:665	better crystallographic and textural characteristics	614:665	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	0	48	theme	BBD-RSM	162:168	arg1	approach					170:177	BBD-RSM approach	162:177	BBD-RSM approach	162:177	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	2	49	from	water	482:486	arg1	removal					441:447	adsorptive removal	430:447	adsorptive removal of Eriochrome black T (EBT) from water	430:486	The resultant composite was employed for adsorptive removal of Eriochrome black T (EBT) from water.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	-C-O					726:729	-C-O	726:729	-C-O	726:729	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	MMO					747:749	MMO	747:749	MMO	747:749	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	-OH					732:734	-OH	732:734	-OH	732:734	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	functionalities					704:718	abundant surface functionalities	687:718	abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO)	687:750	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	-CO					721:723	-CO	721:723	-CO	721:723	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	50	with	B-CuFe-CS	672:680	arg1	-NO3					737:740	-NO3	737:740	-NO3	737:740	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	51	theme	enhanced	776:783	arg1	removal					785:791	enhanced removal	776:791	enhanced removal	776:791	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	8	52	theme	spectroscopic	1227:1239	arg1	analysis					1241:1248	The spectroscopic analysis	1223:1248	The spectroscopic analysis (FTIR and XPS)	1223:1263	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	8	53	theme	experimental	1269:1280	arg1	results					1282:1288	experimental results	1269:1288	experimental results	1269:1288	The spectroscopic analysis (FTIR and XPS) and experimental results suggested that EBT adsorption is mainly governed by electrostatic, chemical and anion-exchange interactions.					
35143802	9	54	theme	dye-contaminated	1551:1566	arg1	streams					1574:1580	dye-contaminated water streams	1551:1580	dye-contaminated water streams	1551:1580	It is evident from these results that coupling B-CuFe composite with bio-filler (chitosan) resulted in an efficient bio-adsorbent to effectively purify dye-contaminated water streams.					
35143802	3	55	theme	crystallographic	621:636	arg1	characteristics					651:665	better crystallographic and textural characteristics	614:665	better crystallographic and textural characteristics	614:665	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	4	56	theme	surface	696:702	arg1	-C-O					726:729	-C-O	726:729	-C-O	726:729	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	56	theme	surface	696:702	arg1	MMO					747:749	MMO	747:749	MMO	747:749	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	56	theme	surface	696:702	arg1	-OH					732:734	-OH	732:734	-OH	732:734	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	56	theme	surface	696:702	arg1	functionalities					704:718	abundant surface functionalities	687:718	abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO)	687:750	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	56	theme	surface	696:702	arg1	-CO					721:723	-CO	721:723	-CO	721:723	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	4	56	theme	surface	696:702	arg1	-NO3					737:740	-NO3	737:740	-NO3	737:740	The B-CuFe-CS with abundant surface functionalities (-CO, -C-O, -OH, -NO3, and MMO), facilitates faster and enhanced removal of the EBT.					
35143802	0	57	theme	biochar/layered	56:70	arg1	composite					105:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	biochar/layered double hydroxide/chitosan hybrid composite	56:113	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	6	58	theme	monolayer	1074:1082	arg1	adsorption					1084:1093	monolayer adsorption	1074:1093	monolayer adsorption	1074:1093	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	5	59	theme	order	868:872	arg1	model					874:878	the pseudo-second order model	850:878	the pseudo-second order model	850:878	The kinetic results showed better fitting to the pseudo-second order model, and equilibrium was achieved within 30 min.					
35143802	6	60	theme	isotherm	994:1001	arg1	R2 > 0.98					1011:1019	R2 > 0.98	1011:1019	R2 > 0.98	1011:1019	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	6	60	theme	isotherm	994:1001	arg1	models					1003:1008	Redlich Peterson isotherm models	977:1008	Redlich Peterson isotherm models (R2 > 0.98)	977:1020	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	7	61	theme	other	1205:1209	arg1	adsorbents					1211:1220	many other adsorbents	1200:1220	many other adsorbents	1200:1220	The maximum adsorption capacity was 806.4 mg/g, which was higher than pristine B-CuFe (476.19 mg/g) and many other adsorbents.					
35143802	0	62	dep	Enhanced	0:7	arg1	optimization					143:154	optimization	143:154	optimization	143:154	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	0	62	dep	Enhanced	0:7	arg1	Performance					116:126	Performance	116:126	Performance	116:126	Enhanced removal of Eriochrome Black T from water using biochar/layered double hydroxide/chitosan hybrid composite: Performance evaluation and optimization using BBD-RSM approach.					
35143802	3	63	theme	Physicochemical	489:503	arg1	characterization					505:520	Physicochemical characterization	489:520	Physicochemical characterization	489:520	Physicochemical characterization indicated that the B-CuFe-CS containing 10 wt % CS exhibited a heterogeneous structure with better crystallographic and textural characteristics.					
35143802	6	64	theme	Peterson	985:992	arg1	R2 > 0.98					1011:1019	R2 > 0.98	1011:1019	R2 > 0.98	1011:1019	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35143802	6	64	theme	Peterson	985:992	arg1	models					1003:1008	Redlich Peterson isotherm models	977:1008	Redlich Peterson isotherm models (R2 > 0.98)	977:1020	Equilibrium data was well explained by Langmuir and Redlich Peterson isotherm models (R2 > 0.98), indicating the EBT removal onto B-CuFe-CS followed monolayer adsorption.					
35830768	1	0	theme	recycled	373:380	arg1	RPET/CNC					416:423	RPET/CNC	416:423	RPET/CNC	416:423	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	0	theme	recycled	373:380	arg1	nanocrystals					402:413	recycled polyester/cellulose nanocrystals	373:413	recycled polyester/cellulose nanocrystals (RPET/CNC)	373:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	0	1	theme	cellulose	87:95	arg1	nanocrystals					97:108	cellulose nanocrystals	87:108	cellulose nanocrystals	87:108	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	1	2	theme	polyester/cellulose	382:400	arg1	RPET/CNC					416:423	RPET/CNC	416:423	RPET/CNC	416:423	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	2	theme	polyester/cellulose	382:400	arg1	nanocrystals					402:413	recycled polyester/cellulose nanocrystals	373:413	recycled polyester/cellulose nanocrystals (RPET/CNC)	373:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	10	3	theme	photochromic	1593:1604	arg1	activity					1606:1613	quick and reversible fluorescence photochromic activity	1559:1613	quick and reversible fluorescence photochromic activity	1559:1613	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	10	4	theme	RPET/CNC	1532:1539	arg1	substrates					1541:1550	the luminescent RPET/CNC substrates	1516:1550	the luminescent RPET/CNC substrates	1516:1550	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	1	5	theme	light	180:184	arg1	protection					186:195	ultraviolet (UV) light protection	163:195	ultraviolet (UV) light protection	163:195	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	6	theme	varying	273:279	arg1	ratios					281:286	varying ratios	273:286	varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	273:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	5	7	theme	spectroscopic	857:869	arg1	profiles					871:878	spectroscopic profiles	857:878	spectroscopic profiles of excitation/emission and decay/lifetime	857:920	Photoluminescence characteristics were also studied using spectroscopic profiles of excitation/emission and decay/lifetime.					
35830768	1	8	theme	nanocrystals	402:413	arg1	nanocrystals					402:413	recycled polyester/cellulose nanocrystals	373:413	recycled polyester/cellulose nanocrystals (RPET/CNC)	373:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	8	theme	nanocrystals	402:413	arg1	composite					360:368	a composite	358:368	a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	358:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	10	9	theme	fluorescence	1580:1591	arg1	activity					1606:1613	quick and reversible fluorescence photochromic activity	1559:1613	quick and reversible fluorescence photochromic activity	1559:1613	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	10	10	theme	luminescent	1520:1530	arg1	substrates					1541:1550	the luminescent RPET/CNC substrates	1516:1550	the luminescent RPET/CNC substrates	1516:1550	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	8	11	contain	had	1305:1307	arg1	window					1298:1303	the afterglow RPET/CNC smart window	1269:1303	the afterglow RPET/CNC smart window	1269:1303	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	8	11	contain	had	1305:1307	arg2	intensities					1325:1335	phosphorescence intensities	1309:1335	phosphorescence intensities of 428, 493, and 523 nm	1309:1359	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	8	12	theme	phosphorescence	1309:1323	arg1	intensities					1325:1335	phosphorescence intensities	1309:1335	phosphorescence intensities of 428, 493, and 523 nm	1309:1359	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	0	13	from	polyester	61:69	arg1	Photoluminescent					0:15	Photoluminescent	0:15	Photoluminescent	0:15	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	0	13	from	polyester	61:69	arg1	window					40:45	photochromic smart window	21:45	photochromic smart window	21:45	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	10	14	theme	reversible	1569:1578	arg1	activity					1606:1613	quick and reversible fluorescence photochromic activity	1559:1613	quick and reversible fluorescence photochromic activity	1559:1613	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	3	15	used	used	515:518	arg2	crosslinker					549:559	crosslinker	549:559	crosslinker	549:559	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	3	15	used	used	515:518	arg2	drier					565:569	drier	565:569	drier	565:569	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	3	15	used	used	515:518	arg2	nanocrystals					497:508	Cellulose nanocrystals	487:508	Cellulose nanocrystals	487:508	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	7	16	dep	Internationale	1185:1198	arg1	l'					1203:1204	Commission Internationale de l'	1174:1204	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	8	17	theme	428	1340:1342	arg1	intensities					1325:1335	phosphorescence intensities	1309:1335	phosphorescence intensities of 428, 493, and 523 nm	1309:1359	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	9	18	theme	hydrophobic	1453:1463	arg1	activity					1465:1472	hydrophobic activity	1453:1472	hydrophobic activity	1453:1472	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	10	19	theme	UV	1631:1632	arg1	radiation					1634:1642	UV radiation	1631:1642	UV radiation	1631:1642	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	4	20	theme	composite	718:726	arg1	bulk					728:731	the recycled polyester/cellulose nanocrystals composite bulk	672:731	the recycled polyester/cellulose nanocrystals composite bulk without agglomeration	672:753	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	4	21	theme	RPET/CNC	778:785	arg1	substrates					787:796	transparent RPET/CNC substrates	766:796	transparent RPET/CNC substrates	766:796	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	5	22	theme	excitation/emission	883:901	arg1	profiles					871:878	spectroscopic profiles	857:878	spectroscopic profiles of excitation/emission and decay/lifetime	857:920	Photoluminescence characteristics were also studied using spectroscopic profiles of excitation/emission and decay/lifetime.					
35830768	9	23	theme	activity	1465:1472	arg1	evidence					1398:1405	evidence	1398:1405	evidence of improved UV shielding, photostability, and hydrophobic activity	1398:1472	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	7	24	theme	nanocomposite	1031:1043	arg1	window					1051:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	1	25	with	windows	117:123	arg1	protection					186:195	ultraviolet (UV) light protection	163:195	ultraviolet (UV) light protection	163:195	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	25	with	windows	117:123	arg1	transparency					203:214	high transparency	198:214	high transparency	198:214	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	25	with	windows	117:123	arg1	phosphorescence					146:160	long-persistent phosphorescence	130:160	long-persistent phosphorescence	130:160	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	25	with	windows	117:123	arg1	rigidity					226:233	high rigidity	221:233	high rigidity	221:233	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	4	26	theme	nanoscale	627:635	arg1	particles					637:645	The phosphor nanoscale particles	614:645	The phosphor nanoscale particles	614:645	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	4	27	theme	phosphor	618:625	arg1	particles					637:645	The phosphor nanoscale particles	614:645	The phosphor nanoscale particles	614:645	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	7	28	theme	smart	1045:1049	arg1	window					1051:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	1	29	theme	high	198:201	arg1	transparency					203:214	high transparency	198:214	high transparency	198:214	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	9	30	theme	photostability	1433:1446	arg1	evidence					1398:1405	evidence	1398:1405	evidence of improved UV shielding, photostability, and hydrophobic activity	1398:1472	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	1	31	theme	lanthanide-activated	291:310	arg1	particles					341:349	lanthanide-activated aluminate phosphor nanoscale particles	291:349	lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	291:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	1	32	theme	Smart	111:115	arg1	windows					117:123	Smart windows	111:123	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity	111:233	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	7	33	theme	waste/cellulose	1002:1016	arg1	nanocrystals					1018:1029	recycled polyester waste/cellulose nanocrystals	983:1029	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	2	34	theme	Cellulose	427:435	arg1	nanocrystals					437:448	Cellulose nanocrystals	427:448	Cellulose nanocrystals	427:448	Cellulose nanocrystals were prepared from rice straw waste.					
35830768	0	35	theme	smart	34:38	arg1	window					40:45	photochromic smart window	21:45	photochromic smart window	21:45	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	1	36	theme	aluminate	312:320	arg1	particles					341:349	lanthanide-activated aluminate phosphor nanoscale particles	291:349	lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	291:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	7	37	theme	laboratory	1221:1230	arg1	parameters					1239:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	6	38	theme	hardness	927:934	arg1	efficiency					936:945	The hardness efficiency	923:945	The hardness efficiency	923:945	The hardness efficiency was also examined.					
35830768	7	39	theme	nanocrystals	1018:1029	arg1	window					1051:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	3	40	theme	low	523:525	arg1	concentration					527:539	low concentration	523:539	low concentration	523:539	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	0	41	theme	photochromic	21:32	arg1	window					40:45	photochromic smart window	21:45	photochromic smart window	21:45	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	1	42	theme	phosphor	322:329	arg1	particles					341:349	lanthanide-activated aluminate phosphor nanoscale particles	291:349	lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	291:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	7	43	theme	colour	1232:1237	arg1	parameters					1239:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	7	44	theme	polyester	992:1000	arg1	nanocrystals					1018:1029	recycled polyester waste/cellulose nanocrystals	983:1029	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	7	45	theme	recycled	983:990	arg1	nanocrystals					1018:1029	recycled polyester waste/cellulose nanocrystals	983:1029	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	2	46	theme	straw	474:478	arg1	waste					480:484	rice straw waste	469:484	rice straw waste	469:484	Cellulose nanocrystals were prepared from rice straw waste.					
35830768	1	47	theme	nanoscale	331:339	arg1	particles					341:349	lanthanide-activated aluminate phosphor nanoscale particles	291:349	lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	291:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	7	48	theme	CIE	1216:1218	arg1	parameters					1239:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	2	49	theme	rice	469:472	arg1	waste					480:484	rice straw waste	469:484	rice straw waste	469:484	Cellulose nanocrystals were prepared from rice straw waste.					
35830768	3	50	theme	Cellulose	487:495	arg1	nanocrystals					497:508	Cellulose nanocrystals	487:508	Cellulose nanocrystals	487:508	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	3	50	theme	Cellulose	487:495	arg1	crosslinker					549:559	crosslinker	549:559	crosslinker	549:559	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	3	50	theme	Cellulose	487:495	arg1	drier					565:569	drier	565:569	drier	565:569	Cellulose nanocrystals were used at low concentration as both crosslinker and drier to improve both transparency and hardness.					
35830768	1	51	theme	high	221:224	arg1	rigidity					226:233	high rigidity	221:233	high rigidity	221:233	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	8	52	theme	523 nm	1354:1359	arg1	intensities					1325:1335	phosphorescence intensities	1309:1335	phosphorescence intensities of 428, 493, and 523 nm	1309:1359	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	1	53	theme	particles	341:349	arg1	ratios					281:286	varying ratios	273:286	varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC)	273:424	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	8	54	theme	493	1345:1347	arg1	intensities					1325:1335	phosphorescence intensities	1309:1335	phosphorescence intensities of 428, 493, and 523 nm	1309:1359	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	10	55	theme	quick	1559:1563	arg1	activity					1606:1613	quick and reversible fluorescence photochromic activity	1559:1613	quick and reversible fluorescence photochromic activity	1559:1613	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	7	56	theme	éclairage	1205:1213	arg1	parameters					1239:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	7	57	theme	transparent	971:981	arg1	window					1051:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window	966:1056	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	7	58	theme	Internationale	1185:1198	arg1	parameters					1239:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	Commission Internationale de l'éclairage (CIE) laboratory colour parameters	1174:1248	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	1	59	theme	long-persistent	130:144	arg1	phosphorescence					146:160	long-persistent phosphorescence	130:160	long-persistent phosphorescence	130:160	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	0	60	theme	recycled	52:59	arg1	polyester					61:69	recycled polyester	52:69	recycled polyester	52:69	Photoluminescent and photochromic smart window from recycled polyester reinforced with cellulose nanocrystals.					
35830768	4	61	theme	transparent	766:776	arg1	substrates					787:796	transparent RPET/CNC substrates	766:796	transparent RPET/CNC substrates	766:796	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	7	62	theme	UV	1096:1097	arg1	light					1099:1103	UV light	1096:1103	UV light to strong green	1096:1119	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	7	63	theme	strong	1108:1113	arg1	green					1115:1119	strong green	1108:1119	strong green	1108:1119	This transparent recycled polyester waste/cellulose nanocrystals nanocomposite smart window has been shown to change colour under UV light to strong green and to greenish-yellow when it is dark, as proved by Commission Internationale de l'éclairage (CIE) laboratory colour parameters.					
35830768	5	64	theme	Photoluminescence	799:815	arg1	characteristics					817:831	Photoluminescence characteristics	799:831	Photoluminescence characteristics	799:831	Photoluminescence characteristics were also studied using spectroscopic profiles of excitation/emission and decay/lifetime.					
35830768	4	65	theme	recycled	676:683	arg1	nanocrystals					705:716	recycled polyester/cellulose nanocrystals	676:716	the recycled polyester/cellulose nanocrystals composite bulk without agglomeration	672:753	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	9	66	theme	improved	1410:1417	arg1	shielding					1422:1430	improved UV shielding	1410:1430	improved UV shielding	1410:1430	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	8	67	theme	afterglow	1273:1281	arg1	window					1298:1303	the afterglow RPET/CNC smart window	1269:1303	the afterglow RPET/CNC smart window	1269:1303	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	1	68	theme	ultraviolet	163:173	arg1	light					180:184	ultraviolet (UV) light	163:184	ultraviolet (UV) light protection	163:195	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	8	69	theme	RPET/CNC	1283:1290	arg1	window					1298:1303	the afterglow RPET/CNC smart window	1269:1303	the afterglow RPET/CNC smart window	1269:1303	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	10	70	dep	ratio	1509:1513	arg1	presence					1482:1489	presence	1482:1489	presence	1482:1489	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	10	70	dep	ratio	1509:1513	arg1	the					1478:1480	the	1478:1480	the	1478:1480	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	8	71	theme	smart	1292:1296	arg1	window					1298:1303	the afterglow RPET/CNC smart window	1269:1303	the afterglow RPET/CNC smart window	1269:1303	It was found that the afterglow RPET/CNC smart window had phosphorescence intensities of 428, 493, and 523 nm upon excitation at 368 nm.					
35830768	9	72	theme	UV	1419:1420	arg1	shielding					1422:1430	improved UV shielding	1410:1430	improved UV shielding	1410:1430	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	10	73	theme	phosphor	1500:1507	arg1	ratio					1509:1513	a low phosphor ratio	1494:1513	a low phosphor ratio	1494:1513	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	4	74	theme	nanocrystals	705:716	arg1	bulk					728:731	the recycled polyester/cellulose nanocrystals composite bulk	672:731	the recycled polyester/cellulose nanocrystals composite bulk without agglomeration	672:753	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35830768	5	75	theme	decay/lifetime	907:920	arg1	profiles					871:878	spectroscopic profiles	857:878	spectroscopic profiles of excitation/emission and decay/lifetime	857:920	Photoluminescence characteristics were also studied using spectroscopic profiles of excitation/emission and decay/lifetime.					
35830768	9	76	theme	shielding	1422:1430	arg1	evidence					1398:1405	evidence	1398:1405	evidence of improved UV shielding, photostability, and hydrophobic activity	1398:1472	There was evidence of improved UV shielding, photostability, and hydrophobic activity.					
35830768	10	77	theme	low	1496:1498	arg1	ratio					1509:1513	a low phosphor ratio	1494:1513	a low phosphor ratio	1494:1513	In the presence of a low phosphor ratio, the luminescent RPET/CNC substrates showed quick and reversible fluorescence photochromic activity when exposed to UV radiation.					
35830768	1	78	theme	UV	176:177	arg1	light					180:184	ultraviolet (UV) light	163:184	ultraviolet (UV) light protection	163:195	Smart windows with long-persistent phosphorescence, ultraviolet (UV) light protection, high transparency, and high rigidity were developed by easily immobilizing varying ratios of lanthanide-activated aluminate phosphor nanoscale particles within a composite of recycled polyester/cellulose nanocrystals (RPET/CNC).					
35830768	4	79	theme	polyester/cellulose	685:703	arg1	nanocrystals					705:716	recycled polyester/cellulose nanocrystals	676:716	the recycled polyester/cellulose nanocrystals composite bulk without agglomeration	672:753	The phosphor nanoscale particles must be distributed into the recycled polyester/cellulose nanocrystals composite bulk without agglomeration to produce transparent RPET/CNC substrates.					
35709870	4	0	theme	hydrophobic	852:862	arg1	interactions					864:875	hydrophobic interactions	852:875	hydrophobic interactions with polymer segments	852:897	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	3	1	theme	buffer	599:604	arg1	substance					606:614	the buffer substance	595:614	the buffer substance	595:614	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	1	2	from	range	275:279	arg1	interaction					121:131	the interaction	117:131	the interaction	117:131	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	2	from	range	275:279	arg1	soluble					261:267	soluble	261:267	soluble	261:267	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	4	3	theme	phase	911:915	arg1	separation					917:926	no phase separation	908:926	no phase separation	908:926	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	3	4	from	dependence	653:662	arg1	enthalpy					711:718	the ionization enthalpy	696:718	the ionization enthalpy of the buffer	696:732	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	4	5	theme	pH	745:746	arg1	pH > 8					756:761	pH > 8	756:761	pH > 8	756:761	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	4	5	theme	pH	745:746	arg1	values					748:753	higher pH values	738:753	higher pH values (pH > 8)	738:762	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	0	6	theme	alkaline	87:94	arg1	media					96:100	alkaline media	87:100	alkaline media	87:100	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	0	7	from	Peculiarities	0:12	arg1	acidic					76:81	acidic	76:81	acidic	76:81	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	0	7	from	Peculiarities	0:12	arg1	media					96:100	alkaline media	87:100	alkaline media	87:100	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	5	8	theme	compositions	1093:1104	arg1	preparation					1050:1060	preparation	1050:1060	preparation of pharmaceutical and cosmetic compositions containing anionic surfactants	1050:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	2	9	theme	RA-CHI/SDS	475:484	arg1	interaction					486:496	RA-CHI/SDS interaction	475:496	RA-CHI/SDS interaction	475:496	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	3	10	theme	ionization	700:709	arg1	enthalpy					711:718	the ionization enthalpy	696:718	the ionization enthalpy of the buffer	696:732	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	4	11	theme	SDS	823:825	arg1	micellization					827:839	SDS micellization	823:839	SDS micellization	823:839	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	5	12	contain	containing	1106:1115	arg1	compositions					1093:1104	pharmaceutical and cosmetic compositions	1065:1104	pharmaceutical and cosmetic compositions containing anionic surfactants	1065:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	5	12	contain	containing	1106:1115	arg2	surfactants					1125:1135	anionic surfactants	1117:1135	anionic surfactants	1117:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	4	13	theme	polymer	882:888	arg1	segments					890:897	polymer segments	882:897	polymer segments	882:897	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	1	14	theme	isothermic	378:387	arg1	ITC					412:414	ITC	412:414	ITC	412:414	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	14	theme	isothermic	378:387	arg1	calorimetry					399:409	isothermic titration calorimetry	378:409	isothermic titration calorimetry (ITC)	378:415	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	15	theme	charged	156:162	arg1	sulfate					190:196	the negatively charged surfactant sodium dodecyl sulfate	141:196	the negatively charged surfactant sodium dodecyl sulfate (SDS)	141:202	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	15	theme	charged	156:162	arg1	SDS					199:201	SDS	199:201	SDS	199:201	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	3	16	from	substance	606:614	arg1	transfer					581:588	proton transfer	574:588	proton transfer from the buffer substance to chitosan	574:626	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	1	17	theme	wide	310:313	arg1	range					318:322	a wide pH range	308:322	a wide pH range including alkaline media	308:347	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	17	theme	wide	310:313	arg1	media					343:347	alkaline media	334:347	alkaline media	334:347	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	18	theme	titration	389:397	arg1	ITC					412:414	ITC	412:414	ITC	412:414	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	18	theme	titration	389:397	arg1	calorimetry					399:409	isothermic titration calorimetry	378:409	isothermic titration calorimetry (ITC)	378:415	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	19	theme	surfactant	164:173	arg1	sulfate					190:196	the negatively charged surfactant sodium dodecyl sulfate	141:196	the negatively charged surfactant sodium dodecyl sulfate (SDS)	141:202	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	19	theme	surfactant	164:173	arg1	SDS					199:201	SDS	199:201	SDS	199:201	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	20	theme	sodium	175:180	arg1	sulfate					190:196	the negatively charged surfactant sodium dodecyl sulfate	141:196	the negatively charged surfactant sodium dodecyl sulfate (SDS)	141:202	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	20	theme	sodium	175:180	arg1	SDS					199:201	SDS	199:201	SDS	199:201	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	0	21	theme	interaction	21:31	arg1	Peculiarities					0:12	Peculiarities	0:12	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.	0:101	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	4	22	with	interactions	864:875	arg1	segments					890:897	polymer segments	882:897	polymer segments	882:897	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	4	23	theme	higher	738:743	arg1	pH > 8					756:761	pH > 8	756:761	pH > 8	756:761	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	4	23	theme	higher	738:743	arg1	values					748:753	higher pH values	738:753	higher pH values (pH > 8)	738:762	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	1	24	theme	dodecyl	182:188	arg1	sulfate					190:196	the negatively charged surfactant sodium dodecyl sulfate	141:196	the negatively charged surfactant sodium dodecyl sulfate (SDS)	141:202	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	24	theme	dodecyl	182:188	arg1	SDS					199:201	SDS	199:201	SDS	199:201	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	2	25	from	exothermic	501:510	arg1	pH 7.4					466:471	pH 7.4	466:471	pH 7.4	466:471	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	2	25	from	exothermic	501:510	arg1	medium					458:463	the weakly alkaline medium	438:463	the weakly alkaline medium (pH 7.4)	438:472	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	2	26	theme	alkaline	449:456	arg1	pH 7.4					466:471	pH 7.4	466:471	pH 7.4	466:471	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	2	26	theme	alkaline	449:456	arg1	medium					458:463	the weakly alkaline medium	438:463	the weakly alkaline medium (pH 7.4)	438:472	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	1	27	theme	pH	315:316	arg1	range					318:322	a wide pH range	308:322	a wide pH range including alkaline media	308:347	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	27	theme	pH	315:316	arg1	media					343:347	alkaline media	334:347	alkaline media	334:347	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	0	28	theme	sodium	36:41	arg1	sulfate					51:57	sodium dodecyl sulfate	36:57	sodium dodecyl sulfate	36:57	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	1	29	dep	pH 12	287:291	arg1	up					281:282	up	281:282	up	281:282	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	2	30	theme	weakly	442:447	arg1	pH 7.4					466:471	pH 7.4	466:471	pH 7.4	466:471	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	2	30	theme	weakly	442:447	arg1	medium					458:463	the weakly alkaline medium	438:463	the weakly alkaline medium (pH 7.4)	438:472	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	5	31	theme	cosmetic	1084:1091	arg1	compositions					1093:1104	pharmaceutical and cosmetic compositions	1065:1104	pharmaceutical and cosmetic compositions containing anionic surfactants	1065:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	4	32	theme	interaction	786:796	arg1	mechanism					773:781	another mechanism	765:781	another mechanism of interaction	765:796	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	3	33	theme	measured	671:678	arg1	release					685:691	the measured heat release	667:691	the measured heat release	667:691	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	0	34	with	interaction	21:31	arg1	chitosan					64:71	chitosan	64:71	chitosan	64:71	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	0	35	theme	sulfate	51:57	arg1	interaction					21:31	the interaction	17:31	the interaction of sodium dodecyl sulfate with chitosan	17:71	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	1	36	theme	pH	272:273	arg1	range					275:279	pH range	272:279	pH range	272:279	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	37	theme	alkaline	334:341	arg1	media					343:347	alkaline media	334:347	alkaline media	334:347	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	0	38	theme	dodecyl	43:49	arg1	sulfate					51:57	sodium dodecyl sulfate	36:57	sodium dodecyl sulfate	36:57	Peculiarities of the interaction of sodium dodecyl sulfate with chitosan in acidic and alkaline media.					
35709870	5	39	theme	pharmaceutical	1065:1078	arg1	compositions					1093:1104	pharmaceutical and cosmetic compositions	1065:1104	pharmaceutical and cosmetic compositions containing anionic surfactants	1065:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	5	40	theme	chitosan	1037:1044	arg1	application					1022:1032	application	1022:1032	application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants	1022:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	3	41	theme	proton	574:579	arg1	transfer					581:588	proton transfer	574:588	proton transfer from the buffer substance to chitosan	574:626	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	3	42	theme	release	685:691	arg1	dependence					653:662	the dependence	649:662	the dependence of the measured heat release on the ionization enthalpy of the buffer	649:732	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	1	43	theme	light	352:356	arg1	LS					370:371	LS	370:371	LS	370:371	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	43	theme	light	352:356	arg1	scattering					358:367	light scattering	352:367	light scattering (LS)	352:372	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	4	44	located	observed	801:808	arg1	pH > 8					756:761	pH > 8	756:761	pH > 8	756:761	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	4	44	located	observed	801:808	arg1	values					748:753	higher pH values	738:753	higher pH values (pH > 8)	738:762	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	4	44	located	observed	801:808	arg2	mechanism					773:781	another mechanism	765:781	another mechanism of interaction	765:796	At higher pH values (pH > 8), another mechanism of interaction is observed that include SDS micellization induced by hydrophobic interactions with polymer segments, so that no phase separation occurred in these mixtures.					
35709870	3	45	theme	buffer	727:732	arg1	enthalpy					711:718	the ionization enthalpy	696:718	the ionization enthalpy of the buffer	696:732	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	2	46	from	medium	458:463	arg1	exothermic					501:510	exothermic	501:510	exothermic	501:510	It is shown that in the weakly alkaline medium (pH 7.4), RA-CHI/SDS interaction is exothermic and cooperative.					
35709870	3	47	theme	heat	680:683	arg1	release					685:691	the measured heat release	667:691	the measured heat release	667:691	This interaction is found to be coupled with proton transfer from the buffer substance to chitosan as it is revealed by the dependence of the measured heat release on the ionization enthalpy of the buffer.					
35709870	5	48	theme	anionic	1117:1123	arg1	surfactants					1125:1135	anionic surfactants	1117:1135	anionic surfactants	1117:1135	The results obtained can contribute to expand the knowledge about application of chitosan for preparation of pharmaceutical and cosmetic compositions containing anionic surfactants.					
35709870	1	49	theme	N-reacetylated	218:231	arg1	RA-CHI					243:248	RA-CHI	243:248	RA-CHI	243:248	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
35709870	1	49	theme	N-reacetylated	218:231	arg1	chitosan					233:240	partially N-reacetylated chitosan	208:240	partially N-reacetylated chitosan (RA-CHI)	208:249	In this work, the interaction between the negatively charged surfactant sodium dodecyl sulfate (SDS) and partially N-reacetylated chitosan (RA-CHI), which is soluble at pH range up to pH 12, is studied in a wide pH range including alkaline media by light scattering (LS) and isothermic titration calorimetry (ITC).					
36056675	9	0	theme	calcium	1587:1593	arg1	ions					1595:1598	calcium ions	1587:1598	calcium ions	1587:1598	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	3	1	theme	biological	611:620	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	2	from	type	425:428	arg1	composition					528:538	the composition	524:538	the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	524:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	0	3	dep	gelatine	127:134	arg1	release					153:159	release	153:159	release	153:159	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	8	4	theme	cells	1453:1457	arg1	viability					1436:1444	the printability and high viability	1410:1444	the printability and high viability of the cells after printing	1410:1472	For the selected material (2A9GM), the printability and high viability of the cells after printing were confirmed.					
36056675	0	5	theme	mechanical	68:77	arg1	properties					79:88	their mechanical properties	62:88	their mechanical properties	62:88	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	9	6	from	change	1647:1652	arg1	viability					1661:1669	the viability	1657:1669	the viability of the cells encapsulated in the bioink	1657:1709	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	7	7	theme	cell	1334:1337	arg1	attachment					1339:1348	cell attachment	1334:1348	cell attachment	1334:1348	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	1	8	theme	Alginate-gelatin	162:177	arg1	hydrogels					179:187	Alginate-gelatin hydrogels	162:187	Alginate-gelatin hydrogels	162:187	Alginate-gelatin hydrogels are the most commonly used materials for 3D bioprinting.					
36056675	1	8	theme	Alginate-gelatin	162:177	arg1	materials					216:224	the most commonly used materials	193:224	the most commonly used materials for 3D bioprinting	193:243	Alginate-gelatin hydrogels are the most commonly used materials for 3D bioprinting.					
36056675	6	9	theme	modulus	1082:1088	arg1	value					1090:1094	the Young's modulus value	1070:1094	the Young's modulus value	1070:1094	Moreover, an increase in gelatin content leads to an increase in the Young's modulus value, irrespectively of the solvent in which the hydrogels were prepared.					
36056675	3	10	from	printability	678:689	arg1	composition					528:538	the composition	524:538	the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	524:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	11	theme	contents	501:508	arg1	type					425:428	the type	421:428	the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	421:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	6	12	theme	gelatin	1030:1036	arg1	content					1038:1044	gelatin content	1030:1044	gelatin content	1030:1044	Moreover, an increase in gelatin content leads to an increase in the Young's modulus value, irrespectively of the solvent in which the hydrogels were prepared.					
36056675	5	13	theme	highest	987:993	arg1	rigidity					995:1002	the highest rigidity	983:1002	the highest rigidity	983:1002	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	7	14	theme	NH2	1286:1288	arg1	groups					1290:1295	free NH and NH2 groups	1274:1295	groups	1290:1295	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	2	15	theme	very	352:355	arg1	composition					357:367	their very composition	346:367	their very composition	346:367	Their printability depends on their properties, and these derive from the way they are prepared and their very composition.					
36056675	6	16	from	increase	1058:1065	arg1	value					1090:1094	the Young's modulus value	1070:1094	the Young's modulus value	1070:1094	Moreover, an increase in gelatin content leads to an increase in the Young's modulus value, irrespectively of the solvent in which the hydrogels were prepared.					
36056675	9	17	theme	amount	1568:1573	arg1	release					1575:1581	gelatin amount release	1560:1581	gelatin amount release	1560:1581	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	3	18	theme	deionized	442:450	arg1	water					452:456	deionized water	442:456	deionized water	442:456	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	7	19	theme	free	1274:1277	arg1	NH					1279:1280	free NH and NH2 groups	1274:1295	NH	1279:1280	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	9	20	theme	cells	1678:1682	arg1	viability					1661:1669	the viability	1657:1669	the viability of the cells encapsulated in the bioink	1657:1709	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	0	21	theme	cell	104:107	arg1	viability					109:117	cell viability	104:117	cell viability	104:117	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	3	22	from	properties	655:664	arg1	composition					528:538	the composition	524:538	the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	524:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	7	23	theme	chemical	1178:1185	arg1	structure					1187:1195	the chemical structure	1174:1195	the chemical structure	1174:1195	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	3	24	dep	hydrogel	543:550	arg1	alginate					563:570	2% wt/vol alginate	553:570	2% wt/vol alginate	553:570	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	25	theme	physicochemical	623:637	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	0	26	theme	Solvent	0:6	arg1	types					8:12	Solvent types	0:12	Solvent types used for the preparation of hydrogels	0:50	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	8	27	theme	selected	1383:1390	arg1	2A9GM					1402:1406	2A9GM	1402:1406	2A9GM	1402:1406	For the selected material (2A9GM), the printability and high viability of the cells after printing were confirmed.					
36056675	8	27	theme	selected	1383:1390	arg1	material					1392:1399	the selected material	1379:1399	the selected material (2A9GM)	1379:1407	For the selected material (2A9GM), the printability and high viability of the cells after printing were confirmed.					
36056675	7	28	theme	culture	1229:1235	arg1	medium					1237:1242	a culture medium	1227:1242	a culture medium for bioink preparation	1227:1265	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	3	29	theme	gelatin	513:519	arg1	contents					501:508	contents	501:508	contents of gelatin	501:519	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	29	theme	gelatin	513:519	arg1	solvent					433:439	solvent	433:439	solvent (deionized water, phosphate buffer, and culture medium)	433:495	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	30	from	hydrogel	543:550	arg1	printability					678:689	printability	678:689	printability	678:689	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	30	from	hydrogel	543:550	arg1	ability					699:705	the ability	695:705	the ability of cells to proliferate in the printed structures	695:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	30	from	hydrogel	543:550	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	5	31	theme	water	873:877	arg1	use					856:858	The use	852:858	The use of deionized water as a solvent	852:890	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	3	32	theme	mechanical	644:653	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	5	33	theme	deionized	863:871	arg1	water					873:877	deionized water	863:877	deionized water	863:877	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	1	34	theme	used	211:214	arg1	hydrogels					179:187	Alginate-gelatin hydrogels	162:187	Alginate-gelatin hydrogels	162:187	Alginate-gelatin hydrogels are the most commonly used materials for 3D bioprinting.					
36056675	1	34	theme	used	211:214	arg1	materials					216:224	the most commonly used materials	193:224	the most commonly used materials for 3D bioprinting	193:243	Alginate-gelatin hydrogels are the most commonly used materials for 3D bioprinting.					
36056675	3	35	theme	study	396:400	arg1	aim					385:387	the aim	381:387	the aim of the study	381:400	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	0	36	theme	calcium	140:146	arg1	ions					148:151	calcium ions	140:151	calcium ions	140:151	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	3	37	theme	9	580:580	arg1	%					581:581	%	581:581	%	581:581	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	5	38	with	polymer	970:976	arg1	rigidity					995:1002	the highest rigidity	983:1002	the highest rigidity	983:1002	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	3	39	dep	alginate	563:570	arg1	wt/vol					583:588	9% wt/vol	580:588	9% wt/vol	580:588	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	39	dep	alginate	563:570	arg1	%					574:574	6%	573:574	6%	573:574	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	39	dep	alginate	563:570	arg1	gelatin					593:599	gelatin	593:599	gelatin	593:599	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	9	40	theme	cross-linking	1529:1541	arg1	agent					1543:1547	the cross-linking agent	1525:1547	the cross-linking agent	1525:1547	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	3	41	theme	solvent	433:439	arg1	type					425:428	the type	421:428	the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	421:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	0	42	theme	hydrogels	42:50	arg1	preparation					27:37	the preparation	23:37	the preparation of hydrogels	23:50	Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release.					
36056675	9	43	theme	agent	1543:1547	arg1	concentration					1508:1520	the concentration	1504:1520	the concentration of the cross-linking agent	1504:1547	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	5	44	theme	cross-linking	925:937	arg1	degree					915:920	the highest degree	903:920	the highest degree of cross-linking of hydrogels	903:950	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	9	45	theme	gelatin	1560:1566	arg1	release					1575:1581	gelatin amount release	1560:1581	gelatin amount release	1560:1581	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	3	46	theme	phosphate	459:467	arg1	buffer					469:474	phosphate buffer	459:474	phosphate buffer	459:474	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	8	47	theme	printability	1414:1425	arg1	viability					1436:1444	the printability and high viability	1410:1444	the printability and high viability of the cells after printing	1410:1472	For the selected material (2A9GM), the printability and high viability of the cells after printing were confirmed.					
36056675	3	48	from	ability	699:705	arg1	composition					528:538	the composition	524:538	the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	524:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	5	49	theme	hydrogels	942:950	arg1	cross-linking					925:937	cross-linking	925:937	cross-linking of hydrogels	925:950	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	3	50	theme	hydrogel	543:550	arg1	composition					528:538	the composition	524:538	the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures	524:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	5	51	theme	highest	907:913	arg1	degree					915:920	the highest degree	903:920	the highest degree of cross-linking of hydrogels	903:950	The use of deionized water as a solvent results in the highest degree of cross-linking of hydrogels, thus obtaining a polymer with the highest rigidity.					
36056675	4	52	theme	hydrogel	814:821	arg1	biocompatible					837:849	biocompatible	837:849	biocompatible	837:849	The results obtained revealed that all the manufactured hydrogel materials are biocompatible.					
36056675	4	52	theme	hydrogel	814:821	arg1	materials					823:831	all the manufactured hydrogel materials	793:831	all the manufactured hydrogel materials	793:831	The results obtained revealed that all the manufactured hydrogel materials are biocompatible.					
36056675	3	53	theme	gelatin	593:599	arg1	wt/vol					583:588	9% wt/vol	580:588	9% wt/vol	580:588	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	53	theme	gelatin	593:599	arg1	%					574:574	6%	573:574	6%	573:574	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	53	theme	gelatin	593:599	arg1	gelatin					593:599	gelatin	593:599	gelatin	593:599	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	6	54	from	increase	1018:1025	arg1	content					1038:1044	gelatin content	1030:1044	gelatin content	1030:1044	Moreover, an increase in gelatin content leads to an increase in the Young's modulus value, irrespectively of the solvent in which the hydrogels were prepared.					
36056675	2	55	dep	way	320:322	arg1	prepared					333:340	prepared	333:340	are prepared	329:340	Their printability depends on their properties, and these derive from the way they are prepared and their very composition.					
36056675	7	56	theme	bioink	1248:1253	arg1	preparation					1255:1265	bioink preparation	1248:1265	bioink preparation	1248:1265	Based on the chemical structure, it is more reasonable to use a culture medium for bioink preparation due to free NH and NH2 groups being present, which are ligands for cell attachment and their proliferation.					
36056675	1	57	theme	3D	230:231	arg1	bioprinting					233:243	3D bioprinting	230:243	3D bioprinting	230:243	Alginate-gelatin hydrogels are the most commonly used materials for 3D bioprinting.					
36056675	4	58	theme	manufactured	801:812	arg1	biocompatible					837:849	biocompatible	837:849	biocompatible	837:849	The results obtained revealed that all the manufactured hydrogel materials are biocompatible.					
36056675	4	58	theme	manufactured	801:812	arg1	materials					823:831	all the manufactured hydrogel materials	793:831	all the manufactured hydrogel materials	793:831	The results obtained revealed that all the manufactured hydrogel materials are biocompatible.					
36056675	3	59	theme	%	581:581	arg1	wt/vol					583:588	9% wt/vol	580:588	9% wt/vol	580:588	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	60	dep	solvent	433:439	arg1	water					452:456	deionized water	442:456	deionized water	442:456	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	60	dep	solvent	433:439	arg1	buffer					469:474	phosphate buffer	459:474	phosphate buffer	459:474	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	60	dep	solvent	433:439	arg1	medium					489:494	culture medium	481:494	culture medium	481:494	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	61	theme	printed	738:744	arg1	structures					746:755	the printed structures	734:755	the printed structures	734:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	62	theme	cells	710:714	arg1	printability					678:689	printability	678:689	printability	678:689	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	62	theme	cells	710:714	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	62	theme	cells	710:714	arg1	ability					699:705	the ability	695:705	the ability of cells to proliferate in the printed structures	695:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	63	theme	%	554:554	arg1	alginate					563:570	2% wt/vol alginate	553:570	2% wt/vol alginate	553:570	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	64	theme	culture	481:487	arg1	medium					489:494	culture medium	481:494	culture medium	481:494	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	65	from	composition	528:538	arg1	printability					678:689	printability	678:689	printability	678:689	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	65	from	composition	528:538	arg1	ability					699:705	the ability	695:705	the ability of cells to proliferate in the printed structures	695:755	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	65	from	composition	528:538	arg1	properties					655:664	their biological, physicochemical, and mechanical properties	605:664	their biological, physicochemical, and mechanical properties	605:664	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	3	66	theme	wt/vol	556:561	arg1	alginate					563:570	2% wt/vol alginate	553:570	2% wt/vol alginate	553:570	Therefore, the aim of the study was to investigate the type of solvent (deionized water, phosphate buffer, and culture medium) and contents of gelatin in the composition of hydrogel (2% wt/vol alginate, 6% and 9% wt/vol of gelatin) on their biological, physicochemical, and mechanical properties, as well as printability and the ability of cells to proliferate in the printed structures.					
36056675	9	67	dep	release	1575:1581	arg1	release					1600:1606	release	1600:1606	release	1600:1606	In this case, the concentration of the cross-linking agent influences gelatin amount release and calcium ions release, and these two processes determine the change in the viability of the cells encapsulated in the bioink.					
36056675	8	68	theme	high	1431:1434	arg1	viability					1436:1444	the printability and high viability	1410:1444	the printability and high viability of the cells after printing	1410:1472	For the selected material (2A9GM), the printability and high viability of the cells after printing were confirmed.					
35617884	3	0	theme	biogenic	643:650	arg1	BAs					660:662	BAs	660:662	BAs	660:662	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	0	theme	biogenic	643:650	arg1	amines					652:657	biogenic amines	643:657	biogenic amines (BAs)	643:663	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	1	theme	communities	901:911	arg1	diversity					878:886	Acinetobacter.The diversity	860:886	Acinetobacter.The diversity of bacterial communities	860:911	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	2	theme	fresh	258:262	arg1	pompano					264:270	fresh pompano	258:270	fresh pompano (Trachinotus ovatus)	258:291	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	3	3	theme	stage	975:979	arg1	end					968:970	the end	964:970	the end of stage	964:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	4	theme	ultrasound-assisted	156:174	arg1	chitosan					176:183	ultrasound-assisted chitosan	156:183	ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage	156:318	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	3	5	theme	high-throughput	762:776	arg1	technology					789:798	high-throughput sequencing technology	762:798	high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage	762:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	6	theme	pompano	264:270	arg1	composition					243:253	microbial composition	233:253	microbial composition	233:253	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	1	6	theme	pompano	264:270	arg1	quality					221:227	quality	221:227	quality	221:227	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	8	7	from	difference	1374:1383	arg1	composition					1398:1408	bacterial composition	1388:1408	bacterial composition	1388:1408	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	2	8	dep	treated	361:367	arg1	grafted					467:473	grafted	467:473	grafted caffeic acid coating with ultrasound-assisted (USG)	467:525	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	3	9	theme	sequencing	778:787	arg1	technology					789:798	high-throughput sequencing technology	762:798	high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage	762:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	8	10	theme	spoilage	1541:1548	arg1	microorganisms					1550:1563	spoilage microorganisms	1541:1563	spoilage microorganisms	1541:1563	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	8	10	theme	spoilage	1541:1548	arg1	microorganisms					1514:1527	microorganisms	1514:1527	microorganisms	1514:1527	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	2	11	theme	caffeic	475:481	arg1	acid					483:486	caffeic acid	475:486	caffeic acid coating with ultrasound-assisted (USG)	475:525	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	8	12	theme	CK	1422:1423	arg1	samples					1437:1443	the CK and treated samples	1418:1443	the CK and treated samples	1418:1443	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	3	13	theme	initial	920:926	arg1	stage					928:932	the initial stage	916:932	the initial stage was more diverse than that at the end of stage	916:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	14	theme	major	818:822	arg1	bacteria					824:831	the major bacteria	814:831	the major bacteria genus of fresh samples	814:854	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	0	15	theme	pompano	113:119	arg1	quality					76:82	quality	76:82	quality	76:82	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	0	15	theme	pompano	113:119	arg1	composition					98:108	microbial composition	88:108	microbial composition	88:108	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	4	16	theme	USG	1022:1024	arg1	treatment					1026:1034	the USG treatment	1018:1034	the USG treatment	1018:1034	With the extension of storage time, the USG treatment could maintain the microbial diversity.					
35617884	3	17	theme	bacteria	824:831	arg1	genus					833:837	the major bacteria genus	814:837	the major bacteria genus of fresh samples	814:854	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	18	theme	chitosan	176:183	arg1	effects					145:151	The effects	141:151	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days	141:330	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	8	19	theme	treated	1429:1435	arg1	samples					1437:1443	the CK and treated samples	1418:1443	the CK and treated samples	1418:1443	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	7	20	from	communities	1257:1267	arg1	treatments					1287:1296	all treatments	1283:1296	all treatments	1283:1296	The microbial communities of samples in all treatments were changed during storage.					
35617884	2	21	theme	grafted	420:426	arg1	G					450:450	G	450:450	G	450:450	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	2	21	theme	grafted	420:426	arg1	coating					441:447	chitosan grafted caffeic acid coating	411:447	chitosan grafted caffeic acid coating (G)	411:451	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	1	22	theme	caffeic	193:199	arg1	acid					201:204	caffeic acid	193:204	caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus)	193:291	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	2	23	theme	chitosan	411:418	arg1	G					450:450	G	450:450	G	450:450	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	2	23	theme	chitosan	411:418	arg1	coating					441:447	chitosan grafted caffeic acid coating	411:447	chitosan grafted caffeic acid coating (G)	411:451	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	8	24	theme	significant	1362:1372	arg1	difference					1374:1383	a significant difference	1360:1383	a significant difference in bacterial composition between the CK and treated samples	1360:1443	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	0	25	dep	quality	76:82	arg1	the					72:74	the	72:74	the	72:74	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	3	26	theme	fresh	842:846	arg1	samples					848:854	fresh samples	842:854	fresh samples	842:854	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	0	27	theme	chitosan	31:38	arg1	Effects					0:6	Effects	0:6	Effects of ultrasound-assisted chitosan	0:38	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	0	28	theme	ice	128:130	arg1	storage					132:138	ice storage	128:138	ice storage	128:138	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	3	29	theme	samples	848:854	arg1	genus					833:837	the major bacteria genus	814:837	the major bacteria genus of fresh samples	814:854	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	0	30	theme	ultrasound-assisted	11:29	arg1	chitosan					31:38	ultrasound-assisted chitosan	11:38	ultrasound-assisted chitosan	11:38	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	5	31	theme	dominant	1080:1087	arg1	Shewanella					1104:1113	Shewanella	1104:1113	Shewanella	1104:1113	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	5	31	theme	dominant	1080:1087	arg1	microbiota					1089:1098	The dominant microbiota	1076:1098	The dominant microbiota	1076:1098	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	5	32	from	Brochothrix	1119:1129	arg1	group					1141:1145	the CK group	1134:1145	the CK group	1134:1145	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	8	33	theme	storage	1341:1347	arg1	end					1334:1336	the end	1330:1336	the end of storage	1330:1347	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	4	34	theme	microbial	1055:1063	arg1	diversity					1065:1073	the microbial diversity	1051:1073	the microbial diversity	1051:1073	With the extension of storage time, the USG treatment could maintain the microbial diversity.					
35617884	4	35	theme	storage	1004:1010	arg1	time					1012:1015	storage time	1004:1015	storage time	1004:1015	With the extension of storage time, the USG treatment could maintain the microbial diversity.					
35617884	0	36	theme	caffeic	48:54	arg1	acid					56:59	caffeic acid	48:59	caffeic acid coating on the quality and microbial composition of pompano during ice storage	48:138	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
35617884	3	37	theme	corrupt	604:610	arg1	TBA					638:640	TBA	638:640	TBA	638:640	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	37	theme	corrupt	604:610	arg1	hypoxanthine					666:677	hypoxanthine	666:677	hypoxanthine (Hx)	666:682	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	37	theme	corrupt	604:610	arg1	substances					612:621	corrupt substances	604:621	corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR)	604:715	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	37	theme	corrupt	604:610	arg1	riboside					702:709	hypoxanthine riboside	689:709	hypoxanthine riboside (HxR)	689:715	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	37	theme	corrupt	604:610	arg1	amines					652:657	biogenic amines	643:657	biogenic amines (BAs)	643:663	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	37	theme	corrupt	604:610	arg1	TVB-N					631:635	TVB-N	631:635	TVB-N	631:635	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	2	38	dep	ultrasound	394:403	arg1	US					406:407	US	406:407	US	406:407	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	4	39	theme	time	1012:1015	arg1	extension					991:999	the extension	987:999	the extension of storage time	987:1015	With the extension of storage time, the USG treatment could maintain the microbial diversity.					
35617884	1	40	theme	ice	308:310	arg1	storage					312:318	ice storage	308:318	ice storage	308:318	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	5	41	from	Shewanella	1104:1113	arg1	group					1141:1145	the CK group	1134:1145	the CK group	1134:1145	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	2	42	theme	acid	436:439	arg1	G					450:450	G	450:450	G	450:450	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	2	42	theme	acid	436:439	arg1	coating					441:447	chitosan grafted caffeic acid coating	411:447	chitosan grafted caffeic acid coating (G)	411:451	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	3	43	theme	hypoxanthine	689:700	arg1	HxR					712:714	HxR	712:714	HxR	712:714	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	43	theme	hypoxanthine	689:700	arg1	riboside					702:709	hypoxanthine riboside	689:709	hypoxanthine riboside (HxR)	689:715	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	7	44	theme	samples	1272:1278	arg1	communities					1257:1267	The microbial communities	1243:1267	The microbial communities of samples in all treatments	1243:1296	The microbial communities of samples in all treatments were changed during storage.					
35617884	6	45	from	Brochothrix	1186:1196	arg1	groups					1209:1214	treated groups	1201:1214	treated groups	1201:1214	In addition, Brochothrix in treated groups was effectively decreased.					
35617884	2	46	theme	caffeic	428:434	arg1	G					450:450	G	450:450	G	450:450	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	2	46	theme	caffeic	428:434	arg1	coating					441:447	chitosan grafted caffeic acid coating	411:447	chitosan grafted caffeic acid coating (G)	411:451	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	6	47	theme	treated	1201:1207	arg1	groups					1209:1214	treated groups	1201:1214	treated groups	1201:1214	In addition, Brochothrix in treated groups was effectively decreased.					
35617884	8	48	theme	microorganisms	1514:1527	arg1	growth					1504:1509	the growth	1500:1509	the growth of microorganisms, especially spoilage microorganisms	1500:1563	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	3	49	theme	Acinetobacter.The	860:876	arg1	diversity					878:886	Acinetobacter.The diversity	860:886	Acinetobacter.The diversity of bacterial communities	860:911	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	5	50	theme	storage	1164:1170	arg1	24 days					1153:1159	24 days	1153:1159	24 days of storage	1153:1170	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	3	51	theme	substances	612:621	arg1	formation					591:599	the formation	587:599	the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR)	587:715	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	52	dep	quality	221:227	arg1	the					217:219	the	217:219	the	217:219	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	3	53	theme	CK	738:739	arg1	results					751:757	the CK group.The results	734:757	the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage	734:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	1	54	theme	microbial	233:241	arg1	composition					243:253	microbial composition	233:253	microbial composition	233:253	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	1	55	dep	pompano	264:270	arg1	ovatus					285:290	Trachinotus ovatus	273:290	Trachinotus ovatus	273:290	The effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of fresh pompano (Trachinotus ovatus) fillets during ice storage for 24 days were evaluated.					
35617884	8	56	theme	quality	1581:1587	arg1	deterioration					1589:1601	the quality deterioration	1577:1601	the quality deterioration caused by bacteria	1577:1620	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	2	57	theme	distilled	372:380	arg1	CK					389:390	CK	389:390	CK	389:390	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	2	57	theme	distilled	372:380	arg1	water					382:386	distilled water	372:386	distilled water (CK)	372:391	Samples were treated by distilled water (CK), ultrasound (US), chitosan grafted caffeic acid coating (G), and chitosan grafted caffeic acid coating with ultrasound-assisted (USG).					
35617884	3	58	theme	group.The	741:749	arg1	results					751:757	the CK group.The results	734:757	the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage	734:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	5	59	theme	CK	1138:1139	arg1	group					1141:1145	the CK group	1134:1145	the CK group	1134:1145	The dominant microbiota was Shewanella and Brochothrix in the CK group after 24 days of storage.					
35617884	8	60	theme	bacterial	1388:1396	arg1	composition					1398:1408	bacterial composition	1388:1408	bacterial composition	1388:1408	At the end of storage, there was a significant difference in bacterial composition between the CK and treated samples, indicating that the treatment can effectively inhibit the growth of microorganisms, especially spoilage microorganisms, and reduce the quality deterioration caused by bacteria.					
35617884	7	61	theme	microbial	1247:1255	arg1	communities					1257:1267	The microbial communities	1243:1267	The microbial communities of samples in all treatments	1243:1296	The microbial communities of samples in all treatments were changed during storage.					
35617884	3	62	theme	bacterial	891:899	arg1	communities					901:911	bacterial communities	891:911	bacterial communities	891:911	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	63	from	stage	928:932	arg1	diversity					878:886	Acinetobacter.The diversity	860:886	Acinetobacter.The diversity of bacterial communities	860:911	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	3	64	theme	technology	789:798	arg1	results					751:757	the CK group.The results	734:757	the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage	734:979	Results showed that samples treated with USG could inhibit the formation of corrupt substances such as TVB-N, TBA, biogenic amines (BAs), hypoxanthine (Hx), and hypoxanthine riboside (HxR) when compared to the CK group.The results of high-throughput sequencing technology observed that the major bacteria genus of fresh samples was Acinetobacter.The diversity of bacterial communities at the initial stage was more diverse than that at the end of stage.					
35617884	0	65	theme	microbial	88:96	arg1	composition					98:108	microbial composition	88:108	microbial composition	88:108	Effects of ultrasound-assisted chitosan grafted caffeic acid coating on the quality and microbial composition of pompano during ice storage.					
36368363	0	0	theme	anti-oxidation	84:97	arg1	abilities					111:119	high anti-oxidation and anti-UV abilities	79:119	high anti-oxidation and anti-UV abilities	79:119	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	6	1	theme	radical	817:823	arg1	rate					836:839	The free radical scavenging rate	808:839	The free radical scavenging rate of CCA film and CCAF film	808:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	5	2	theme	%	805:805	arg1	increase					788:795	an increase	785:795	an increase of 73.5 %	785:805	The TS of the CCAF film increased from 42.6 MPa to 73.9 MPa with an increase of 73.5 %.					
36368363	4	3	theme	pure	700:703	arg1	film					714:717	pure chitosan film	700:717	pure chitosan film	700:717	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	6	4	theme	pure	885:888	arg1	film					899:902	pure chitosan film	885:902	pure chitosan film	885:902	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	0	5	theme	high	79:82	arg1	abilities					111:119	high anti-oxidation and anti-UV abilities	79:119	high anti-oxidation and anti-UV abilities	79:119	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	6	6	theme	free	812:815	arg1	rate					836:839	The free radical scavenging rate	808:839	The free radical scavenging rate of CCA film and CCAF film	808:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	3	7	theme	tensile	473:479	arg1	TS					491:492	TS	491:492	TS	491:492	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	3	7	theme	tensile	473:479	arg1	strength					481:488	the tensile strength	469:488	the tensile strength (TS)	469:493	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	1	8	theme	CCAF	235:238	arg1	films					251:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	0	9	theme	anti-UV	103:109	arg1	abilities					111:119	high anti-oxidation and anti-UV abilities	79:119	high anti-oxidation and anti-UV abilities	79:119	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	7	10	theme	resistance	965:974	arg1	property					976:983	The UV resistance property	958:983	The UV resistance property of the CCAF solution	958:1004	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	7	11	theme	UV	1059:1060	arg1	rate					1070:1073	the UV barrier rate	1055:1073	the UV barrier rate	1055:1073	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	9	12	theme	more	1357:1360	arg1	applications					1362:1373	more applications	1357:1373	more applications	1357:1373	Besides, the composite film also showed excellent antibacterial properties, which provided the possibility for more applications.					
36368363	8	13	theme	CCAF	1165:1168	arg1	film					1170:1173	CCAF film	1165:1173	CCAF film	1165:1173	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	1	14	theme	composite	241:249	arg1	films					251:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	0	15	link	Multi-crosslinked	0:16	arg1	films					35:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	4	16	theme	chitosan	705:712	arg1	film					714:717	pure chitosan film	700:717	pure chitosan film	700:717	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	7	17	theme	UV	962:963	arg1	property					976:983	The UV resistance property	958:983	The UV resistance property of the CCAF solution	958:1004	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	0	18	theme	Multi-crosslinked	0:16	arg1	films					35:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	3	19	theme	covalent	408:415	arg1	bonds					417:421	covalent bonds	408:421	covalent bonds	408:421	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	0	20	theme	network	18:24	arg1	films					35:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	7	21	theme	barrier	1062:1068	arg1	rate					1070:1073	the UV barrier rate	1055:1073	the UV barrier rate	1055:1073	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	3	22	used	used	327:330	arg2	Fe3+					318:321	Fe3+	318:321	Fe3+	318:321	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	2	23	theme	covalent	283:290	arg1	bonds					292:296	covalent bonds	283:296	covalent bonds	283:296	CA was used to introduce covalent bonds and hydrogen bonds.					
36368363	3	24	theme	hydrogen	390:397	arg1	bond					399:402	hydrogen bond	390:402	hydrogen bond	390:402	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	3	25	theme	coordination	351:362	arg1	bonds					364:368	metal coordination bonds	345:368	metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance	345:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	4	26	theme	CA	659:660	arg1	addition					638:645	the addition	634:645	the addition of 0.3 mmol CA	634:660	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	5	27	theme	CCAF	734:737	arg1	film					739:742	the CCAF film	730:742	the CCAF film	730:742	The TS of the CCAF film increased from 42.6 MPa to 73.9 MPa with an increase of 73.5 %.					
36368363	6	28	theme	film	862:865	arg1	rate					836:839	The free radical scavenging rate	808:839	The free radical scavenging rate of CCA film and CCAF film	808:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	8	29	theme	25.71 	1189:1194	arg1	reduction					1197:1205	a 25.71 % reduction	1187:1205	a 25.71 % reduction	1187:1205	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	30	theme	vapor	1102:1106	arg1	WVT					1122:1124	The water vapor transmission (WVT) and water vapor permeability	1092:1154	WVT	1122:1124	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	30	theme	vapor	1102:1106	arg1	WVP					1157:1159	WVP	1157:1159	WVP	1157:1159	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	0	31	theme	chitosan	26:33	arg1	films					35:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films	0:39	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	6	32	theme	CCAF	857:860	arg1	film					862:865	CCAF film	857:865	CCAF film	857:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	8	33	theme	film	1170:1173	arg1	permeability					1143:1154	The water vapor transmission (WVT) and water vapor permeability	1092:1154	permeability	1143:1154	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	33	theme	film	1170:1173	arg1	WVT					1122:1124	The water vapor transmission (WVT) and water vapor permeability	1092:1154	WVT	1122:1124	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	33	theme	film	1170:1173	arg1	WVP					1157:1159	WVP	1157:1159	WVP	1157:1159	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	3	34	theme	antioxidant	508:518	arg1	properties					520:529	the antioxidant properties	504:529	the antioxidant properties	504:529	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	8	35	theme	water	1096:1100	arg1	WVT					1122:1124	The water vapor transmission (WVT) and water vapor permeability	1092:1154	WVT	1122:1124	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	35	theme	water	1096:1100	arg1	WVP					1157:1159	WVP	1157:1159	WVP	1157:1159	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	0	36	theme	caffeic	52:58	arg1	acid					60:63	caffeic acid	52:63	caffeic acid	52:63	Multi-crosslinked network chitosan films containing caffeic acid and Fe3+ with high anti-oxidation and anti-UV abilities.					
36368363	9	37	theme	excellent	1286:1294	arg1	properties					1310:1319	excellent antibacterial properties	1286:1319	excellent antibacterial properties	1286:1319	Besides, the composite film also showed excellent antibacterial properties, which provided the possibility for more applications.					
36368363	4	38	theme	chitosan/caffeic	596:611	arg1	CCA					619:621	CCA	619:621	CCA	619:621	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	4	38	theme	chitosan/caffeic	596:611	arg1	acid					613:616	chitosan/caffeic acid	596:616	chitosan/caffeic acid (CCA) film	596:627	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	1	39	theme	chitosan	178:185	arg1	solution					187:194	chitosan solution	178:194	chitosan solution	178:194	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	6	40	theme	film	848:851	arg1	rate					836:839	The free radical scavenging rate	808:839	The free radical scavenging rate of CCA film and CCAF film	808:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	8	41	theme	vapor	1137:1141	arg1	permeability					1143:1154	The water vapor transmission (WVT) and water vapor permeability	1092:1154	permeability	1143:1154	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	6	42	theme	chitosan	890:897	arg1	film					899:902	pure chitosan film	885:902	pure chitosan film	885:902	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	8	43	theme	transmission	1108:1119	arg1	WVT					1122:1124	The water vapor transmission (WVT) and water vapor permeability	1092:1154	WVT	1122:1124	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	43	theme	transmission	1108:1119	arg1	WVP					1157:1159	WVP	1157:1159	WVP	1157:1159	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	7	44	theme	CCAF	992:995	arg1	solution					997:1004	the CCAF solution	988:1004	the CCAF solution	988:1004	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	6	45	theme	CCA	844:846	arg1	film					848:851	CCA film	844:851	CCA film	844:851	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	3	46	link	multi-crosslinked	433:449	arg1	system					451:456	a multi-crosslinked system	431:456	a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance	431:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	3	47	theme	UV	535:536	arg1	performance					549:559	UV resistance performance	535:559	UV resistance performance	535:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	4	48	theme	0.3 mmol	650:657	arg1	CA					659:660	0.3 mmol CA	650:660	0.3 mmol CA	650:660	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	7	49	theme	solution	997:1004	arg1	property					976:983	The UV resistance property	958:983	The UV resistance property of the CCAF solution	958:1004	The UV resistance property of the CCAF solution was tested at 365 nm and the results showed that the UV barrier rate reached 99.99 %.					
36368363	9	50	theme	antibacterial	1296:1308	arg1	properties					1310:1319	excellent antibacterial properties	1286:1319	excellent antibacterial properties	1286:1319	Besides, the composite film also showed excellent antibacterial properties, which provided the possibility for more applications.					
36368363	3	51	theme	resistance	538:547	arg1	performance					549:559	UV resistance performance	535:559	UV resistance performance	535:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	9	52	theme	composite	1259:1267	arg1	film					1269:1272	the composite film	1255:1272	the composite film	1255:1272	Besides, the composite film also showed excellent antibacterial properties, which provided the possibility for more applications.					
36368363	2	53	theme	hydrogen	302:309	arg1	bonds					311:315	hydrogen bonds	302:315	hydrogen bonds	302:315	CA was used to introduce covalent bonds and hydrogen bonds.					
36368363	2	54	used	used	265:268	arg2	CA					258:259	CA	258:259	CA	258:259	CA was used to introduce covalent bonds and hydrogen bonds.					
36368363	8	55	theme	%	1195:1195	arg1	reduction					1197:1205	a 25.71 % reduction	1187:1205	a 25.71 % reduction	1187:1205	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	3	56	theme	multi-crosslinked	433:449	arg1	system					451:456	a multi-crosslinked system	431:456	a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance	431:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	3	57	dep	enhance	461:467	arg1	improve					496:502	improve	496:502	improve the antioxidant properties and UV resistance performance	496:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	4	58	with	TS	590:591	arg1	addition					638:645	the addition	634:645	the addition of 0.3 mmol CA	634:660	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	5	59	theme	film	739:742	arg1	TS					724:725	The TS	720:725	The TS of the CCAF film	720:742	The TS of the CCAF film increased from 42.6 MPa to 73.9 MPa with an increase of 73.5 %.					
36368363	4	60	theme	film	624:627	arg1	TS					590:591	the TS	586:591	the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA	586:660	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	8	61	theme	water	1131:1135	arg1	permeability					1143:1154	The water vapor transmission (WVT) and water vapor permeability	1092:1154	permeability	1143:1154	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	8	62	theme	chitosan	1231:1238	arg1	film					1240:1243	the chitosan film	1227:1243	the chitosan film	1227:1243	The water vapor transmission (WVT) and water vapor permeability (WVP) of CCAF film both showed a 25.71 % reduction compared to that of the chitosan film.					
36368363	1	63	theme	caffeic	137:143	arg1	acid					145:148	caffeic acid	137:148	caffeic acid (CA)	137:153	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	1	63	theme	caffeic	137:143	arg1	CA					151:152	CA	151:152	CA	151:152	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	4	64	theme	acid	613:616	arg1	film					624:627	chitosan/caffeic acid (CCA) film	596:627	chitosan/caffeic acid (CCA) film	596:627	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	1	65	theme	chitosan/caffeic	207:222	arg1	films					251:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36368363	6	66	theme	scavenging	825:834	arg1	rate					836:839	The free radical scavenging rate	808:839	The free radical scavenging rate of CCA film and CCAF film	808:865	The free radical scavenging rate of CCA film and CCAF film, in comparison to pure chitosan film, were improved by 155.7 % and 148.24 %, respectively.					
36368363	4	67	dep	increased	666:674	arg1	compared					686:693	compared	686:693	compared with pure chitosan film	686:717	The results showed that the TS of chitosan/caffeic acid (CCA) film with the addition of 0.3 mmol CA was increased by 36.6 % compared with pure chitosan film.					
36368363	3	68	theme	metal	345:349	arg1	bonds					364:368	metal coordination bonds	345:368	metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance	345:559	Fe3+ was used to introduce metal coordination bonds which combined with hydrogen bond and covalent bonds to form a multi-crosslinked system to enhance the tensile strength (TS), improve the antioxidant properties and UV resistance performance.					
36368363	1	69	theme	acid/Fe3+	224:232	arg1	films					251:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	chitosan/caffeic acid/Fe3+ (CCAF) composite films	207:255	In this study, caffeic acid (CA) and Fe3+ were added to chitosan solution to prepare chitosan/caffeic acid/Fe3+ (CCAF) composite films.					
36235046	9	0	theme	compressive	1188:1198	arg1	strength					1200:1207	The compressive strength	1184:1207	The compressive strength of the composite cellulose aerogel with durian rind-based CNF	1184:1269	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	4	1	theme	good	510:513	arg1	dispersion					515:524	good dispersion	510:524	good dispersion	510:524	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	5	2	theme	durian	782:787	arg1	CNF					800:802	durian rind-based CNF	782:802	durian rind-based CNF	782:802	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	6	3	theme	CNF	926:928	arg1	concentration					909:921	the concentration	905:921	the concentration of CNF	905:928	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	6	4	theme	significant	936:946	arg1	effect					948:953	a significant effect	934:953	a significant effect	934:953	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	0	5	from	Preparation	6:16	arg1	Aerogel					82:88	Aerogel	82:88	Aerogel	82:88	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	7	6	theme	sheet	1055:1059	arg1	structure					1061:1069	a sheet structure	1053:1069	a sheet structure	1053:1069	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	2	7	theme	treatment	317:325	arg1	power					297:301	The power	293:301	The power of ultrasonic treatment	293:325	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	7	8	theme	1	1036:1036	arg1	%					1037:1037	%	1037:1037	%	1037:1037	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	3	9	theme	several	482:488	arg1	micrometers					490:500	several micrometers	482:500	several micrometers	482:500	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	9	10	with	strength	1200:1207	arg1	CNF					1267:1269	durian rind-based CNF	1249:1269	durian rind-based CNF	1249:1269	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	1	11	theme	agricultural	230:241	arg1	rinds					269:273	agricultural and forestry waste durian rinds	230:273	agricultural and forestry waste durian rinds	230:273	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	11	theme	agricultural	230:241	arg1	materials					282:290	raw materials	278:290	raw materials	278:290	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	7	12	theme	compression	1113:1123	arg1	performance					1125:1135	the strongest compression performance	1099:1135	the strongest compression performance	1099:1135	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	9	13	theme	composite	1216:1224	arg1	aerogel					1236:1242	the composite cellulose aerogel	1212:1242	the composite cellulose aerogel	1212:1242	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	3	14	theme	micrometers	490:500	arg1	diameter					446:453	a diameter	444:453	a diameter of 8-20 nm	444:464	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	3	14	theme	micrometers	490:500	arg1	length					472:477	a length	470:477	a length of several micrometers	470:500	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	4	15	theme	form	588:591	arg1	hydrogel					593:600	form hydrogel	588:600	form hydrogel	588:600	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	5	16	theme	microscopic	669:679	arg1	morphology					681:690	microscopic morphology	669:690	microscopic morphology	669:690	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	3	17	contain	had	440:442	arg2	length					472:477	a length	470:477	a length of several micrometers	470:500	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	3	17	contain	had	440:442	arg2	diameter					446:453	a diameter	444:453	a diameter of 8-20 nm	444:464	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	3	17	contain	had	440:442	arg1	CNF					436:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	5	18	theme	rind-based	789:798	arg1	CNF					800:802	durian rind-based CNF	782:802	durian rind-based CNF	782:802	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	2	19	theme	molecular	375:383	arg1	weight					385:390	low molecular weight	371:390	low molecular weight liquid DMSO	371:402	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	1	20	theme	energy	140:145	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	5	21	theme	composite	739:747	arg1	aerogels					759:766	composite cellulose aerogels	739:766	composite cellulose aerogels	739:766	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	6	22	dep	microstructure	962:975	arg1	the					958:960	the	958:960	the	958:960	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	5	23	theme	CNF	722:724	arg1	aerogels					726:733	CNF aerogels	722:733	CNF aerogels	722:733	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	5	24	theme	aerogels	759:766	arg1	morphology					681:690	microscopic morphology	669:690	microscopic morphology	669:690	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	5	24	theme	aerogels	759:766	arg1	properties					708:717	compressive properties	696:717	compressive properties	696:717	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	1	25	theme	consumption	147:157	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	5	26	theme	cellulose	749:757	arg1	aerogels					759:766	composite cellulose aerogels	739:766	composite cellulose aerogels	739:766	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	9	27	theme	durian	1249:1254	arg1	CNF					1267:1269	durian rind-based CNF	1249:1269	durian rind-based CNF	1249:1269	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	4	28	contain	had	506:508	arg1	It					503:504	It	503:504	It	503:504	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	4	28	contain	had	506:508	arg2	stability					530:538	stability	530:538	stability	530:538	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	4	28	contain	had	506:508	arg2	dispersion					515:524	good dispersion	510:524	good dispersion	510:524	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	9	29	theme	cellulose	1226:1234	arg1	aerogel					1236:1242	the composite cellulose aerogel	1212:1242	the composite cellulose aerogel	1212:1242	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	1	30	theme	preparation	159:169	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	0	31	theme	Green	0:4	arg1	Preparation					6:16	Green Preparation	0:16	Green Preparation of Durian Rind-Based Cellulose Nanofiber	0:57	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	1	32	theme	forestry	247:254	arg1	rinds					269:273	agricultural and forestry waste durian rinds	230:273	agricultural and forestry waste durian rinds	230:273	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	32	theme	forestry	247:254	arg1	materials					282:290	raw materials	278:290	raw materials	278:290	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	6	33	contain	had	930:932	arg1	concentration					909:921	the concentration	905:921	the concentration of CNF	905:928	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	6	33	contain	had	930:932	arg2	effect					948:953	a significant effect	934:953	a significant effect	934:953	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	4	34	theme	room	605:608	arg1	temperature					610:620	room temperature	605:620	room temperature	605:620	It had good dispersion and stability in water, and could spontaneously cross-link to form hydrogel at room temperature when the concentration was more than 0.5%.					
36235046	0	35	theme	Durian	21:26	arg1	Nanofiber					49:57	Durian Rind-Based Cellulose Nanofiber	21:57	Durian Rind-Based Cellulose Nanofiber	21:57	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	1	36	theme	waste	256:260	arg1	rinds					269:273	agricultural and forestry waste durian rinds	230:273	agricultural and forestry waste durian rinds	230:273	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	36	theme	waste	256:260	arg1	materials					282:290	raw materials	278:290	raw materials	278:290	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	7	37	contain	had	1095:1097	arg1	structure					1061:1069	a sheet structure	1053:1069	a sheet structure	1053:1069	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	7	37	contain	had	1095:1097	arg2	performance					1125:1135	the strongest compression performance	1099:1135	the strongest compression performance	1099:1135	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	6	38	theme	mechanical	981:990	arg1	properties					992:1001	mechanical properties	981:1001	mechanical properties	981:1001	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	2	39	theme	weight	385:390	arg1	DMSO					399:402	low molecular weight liquid DMSO	371:402	low molecular weight liquid DMSO	371:402	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	2	40	theme	liquid	392:397	arg1	DMSO					399:402	low molecular weight liquid DMSO	371:402	low molecular weight liquid DMSO	371:402	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	1	41	theme	durian	262:267	arg1	rinds					269:273	agricultural and forestry waste durian rinds	230:273	agricultural and forestry waste durian rinds	230:273	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	41	theme	durian	262:267	arg1	materials					282:290	raw materials	278:290	raw materials	278:290	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	7	42	theme	CNF	1019:1021	arg1	aerogel					1023:1029	The CNF aerogel	1015:1029	The CNF aerogel with 1% CNF	1015:1041	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	1	43	theme	low	136:138	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	44	theme	cellulose	181:189	arg1	CNF					202:204	CNF	202:204	CNF	202:204	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	44	theme	cellulose	181:189	arg1	nanofiber					191:199	cellulose nanofiber	181:199	cellulose nanofiber (CNF)	181:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	0	45	theme	Cellulose	39:47	arg1	Nanofiber					49:57	Durian Rind-Based Cellulose Nanofiber	21:57	Durian Rind-Based Cellulose Nanofiber	21:57	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	7	46	theme	strongest	1103:1111	arg1	performance					1125:1135	the strongest compression performance	1099:1135	the strongest compression performance	1099:1135	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	2	47	theme	low	371:373	arg1	weight					385:390	low molecular weight	371:390	low molecular weight liquid DMSO	371:402	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	6	48	theme	aerogel	1006:1012	arg1	properties					992:1001	mechanical properties	981:1001	mechanical properties	981:1001	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	6	48	theme	aerogel	1006:1012	arg1	microstructure					962:975	microstructure	962:975	microstructure	962:975	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	1	49	theme	nanofiber	191:199	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	0	50	theme	Rind-Based	28:37	arg1	Nanofiber					49:57	Durian Rind-Based Cellulose Nanofiber	21:57	Durian Rind-Based Cellulose Nanofiber	21:57	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	5	51	theme	aerogels	726:733	arg1	morphology					681:690	microscopic morphology	669:690	microscopic morphology	669:690	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	5	51	theme	aerogels	726:733	arg1	properties					708:717	compressive properties	696:717	compressive properties	696:717	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	0	52	from	Application	67:77	arg1	Aerogel					82:88	Aerogel	82:88	Aerogel	82:88	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	3	53	theme	durian	418:423	arg1	CNF					436:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	8	54	theme	CNF	1154:1156	arg1	aerogels					1158:1165	CNF aerogels	1154:1165	CNF aerogels	1154:1165	The porosity of CNF aerogels was high to 99%.					
36235046	1	55	theme	raw	278:280	arg1	rinds					269:273	agricultural and forestry waste durian rinds	230:273	agricultural and forestry waste durian rinds	230:273	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	1	55	theme	raw	278:280	arg1	materials					282:290	raw materials	278:290	raw materials	278:290	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	9	56	theme	rind-based	1256:1265	arg1	CNF					1267:1269	durian rind-based CNF	1249:1269	durian rind-based CNF	1249:1269	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	9	57	theme	aerogel	1236:1242	arg1	strength					1200:1207	The compressive strength	1184:1207	The compressive strength of the composite cellulose aerogel with durian rind-based CNF	1184:1269	The compressive strength of the composite cellulose aerogel with durian rind-based CNF was effectively enhanced.					
36235046	2	58	theme	ultrasonic	306:315	arg1	treatment					317:325	ultrasonic treatment	306:325	ultrasonic treatment	306:325	The power of ultrasonic treatment was successfully reduced to only 360 W with low molecular weight liquid DMSO.					
36235046	0	59	theme	Nanofiber	49:57	arg1	Preparation					6:16	Green Preparation	0:16	Green Preparation of Durian Rind-Based Cellulose Nanofiber	0:57	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	0	59	theme	Nanofiber	49:57	arg1	Application					67:77	Its Application	63:77	Its Application in Aerogel	63:88	Green Preparation of Durian Rind-Based Cellulose Nanofiber and Its Application in Aerogel.					
36235046	5	60	dep	morphology	681:690	arg1	The					665:667	The	665:667	The	665:667	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	7	61	theme	%	1037:1037	arg1	CNF					1039:1041	1% CNF	1036:1041	1% CNF	1036:1041	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	3	62	theme	nm	463:464	arg1	diameter					446:453	a diameter	444:453	a diameter of 8-20 nm	444:464	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	3	62	theme	nm	463:464	arg1	length					472:477	a length	470:477	a length of several micrometers	470:500	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	1	63	theme	green	108:112	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	8	64	dep	99	1179:1180	arg1	to					1176:1177	to	1176:1177	to	1176:1177	The porosity of CNF aerogels was high to 99%.					
36235046	7	65	with	aerogel	1023:1029	arg1	CNF					1039:1041	1% CNF	1036:1041	1% CNF	1036:1041	The CNF aerogel with 1% CNF exhibited a sheet structure braced by fibers, which had the strongest compression performance.					
36235046	3	66	theme	obtained	409:416	arg1	CNF					436:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	3	67	theme	rind-based	425:434	arg1	CNF					436:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF	405:438	The obtained durian rind-based CNF had a diameter of 8-20 nm and a length of several micrometers.					
36235046	8	68	theme	aerogels	1158:1165	arg1	porosity					1142:1149	The porosity	1138:1149	The porosity of CNF aerogels	1138:1165	The porosity of CNF aerogels was high to 99%.					
36235046	8	68	theme	aerogels	1158:1165	arg1	%					1181:1181	high to 99%	1171:1181	high to 99%	1171:1181	The porosity of CNF aerogels was high to 99%.					
36235046	5	69	theme	compressive	696:706	arg1	properties					708:717	compressive properties	696:717	compressive properties	696:717	The microscopic morphology and compressive properties of CNF aerogels and composite cellulose aerogels prepared from durian rind-based CNF were evaluated.					
36235046	6	70	theme	volume	872:877	arg1	shrinkage					879:887	the volume shrinkage	868:887	the volume shrinkage of aerogel	868:898	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
36235046	1	71	theme	efficient	122:130	arg1	method					171:176	a green, highly efficient and low energy consumption preparation method	106:176	a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF)	106:205	In this study, a green, highly efficient and low energy consumption preparation method of cellulose nanofiber (CNF) was developed by using agricultural and forestry waste durian rinds as raw materials.					
36235046	6	72	theme	aerogel	892:898	arg1	shrinkage					879:887	the volume shrinkage	868:887	the volume shrinkage of aerogel	868:898	It was found that CNF could effectively prevent the volume shrinkage of aerogel, and the concentration of CNF had a significant effect on the microstructure and mechanical properties of aerogel.					
37119898	0	0	theme	Kyoho	83:87	arg1	preservation					96:107	Kyoho grapes preservation	83:107	Kyoho grapes preservation	83:107	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	7	1	theme	active	1148:1153	arg1	material					1155:1162	an active material	1145:1162	an active material for food packaging	1145:1181	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	7	1	theme	active	1148:1153	arg1	membranes					1079:1087	nanofibrous composite membranes	1057:1087	nanofibrous composite membranes based on CS-Nano-ZnO and Cur	1057:1116	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	7	2	theme	composite	1069:1077	arg1	material					1155:1162	an active material	1145:1162	an active material for food packaging	1145:1181	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	7	2	theme	composite	1069:1077	arg1	membranes					1079:1087	nanofibrous composite membranes	1057:1087	nanofibrous composite membranes based on CS-Nano-ZnO and Cur	1057:1116	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	2	3	contain	had	404:406	arg2	PDI = 0.32 ± 0.10					495:511	PDI = 0.32 ± 0.10	495:511	PDI = 0.32 ± 0.10	495:511	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	3	contain	had	404:406	arg2	distribution					481:492	a generally uniform particle size distribution	447:492	a generally uniform particle size distribution (PDI = 0.32 ± 0.10)	447:512	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	3	contain	had	404:406	arg2	size					418:421	a minimum size	408:421	a minimum size (404.67 ± 42.35 nm)	408:441	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	3	contain	had	404:406	arg2	404.67 ± 42.35 nm					424:440	404.67 ± 42.35 nm	424:440	404.67 ± 42.35 nm	424:440	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	3	contain	had	404:406	arg1	CS-Nano-ZnO					392:402	the prepared CS-Nano-ZnO	379:402	the prepared CS-Nano-ZnO	379:402	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	7	4	theme	nanofibrous	1057:1067	arg1	material					1155:1162	an active material	1145:1162	an active material for food packaging	1145:1181	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	7	4	theme	nanofibrous	1057:1067	arg1	membranes					1079:1087	nanofibrous composite membranes	1057:1087	nanofibrous composite membranes based on CS-Nano-ZnO and Cur	1057:1116	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	5	5	theme	good	940:943	arg1	fruit					945:949	good fruit	940:949	good fruit	940:949	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	0	6	theme	grapes	89:94	arg1	preservation					96:107	Kyoho grapes preservation	83:107	Kyoho grapes preservation	83:107	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	5	7	theme	fruit	945:949	arg1	rate					932:935	a higher rate	923:935	a higher rate of good fruit (60.25 ± 1.46 %)	923:966	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	5	7	theme	fruit	945:949	arg1	%					965:965	60.25 ± 1.46 %	952:965	60.25 ± 1.46 %	952:965	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	5	7	theme	fruit	945:949	arg1	quality					911:917	good quality	906:917	good quality	906:917	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	3	8	theme	composite	519:527	arg1	membrane					535:542	The composite fiber membrane	515:542	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5	515:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	7	9	used	used	1137:1140	arg2	membranes					1079:1087	nanofibrous composite membranes	1057:1087	nanofibrous composite membranes based on CS-Nano-ZnO and Cur	1057:1116	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	7	9	used	used	1137:1140	arg2	material					1155:1162	an active material	1145:1162	an active material for food packaging	1145:1181	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	5	10	theme	grape	837:841	arg1	berries					843:849	grape berries	837:849	grape berries wrapped with composite fiber membrane	837:887	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	2	11	theme	size	476:479	arg1	distribution					481:492	a generally uniform particle size distribution	447:492	a generally uniform particle size distribution (PDI = 0.32 ± 0.10)	447:512	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	11	theme	size	476:479	arg1	PDI = 0.32 ± 0.10					495:511	PDI = 0.32 ± 0.10	495:511	PDI = 0.32 ± 0.10	495:511	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	0	12	theme	Nanofibrous	0:10	arg1	membranes					22:30	Nanofibrous composite membranes	0:30	Nanofibrous composite membranes	0:30	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	0	13	theme	composite	12:20	arg1	membranes					22:30	Nanofibrous composite membranes	0:30	Nanofibrous composite membranes	0:30	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	1	14	theme	sodium	181:186	arg1	SA					198:199	SA	198:199	SA	198:199	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	14	theme	sodium	181:186	arg1	alginate					188:195	sodium alginate	181:195	sodium alginate (SA)	181:200	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	2	15	theme	minimum	410:416	arg1	404.67 ± 42.35 nm					424:440	404.67 ± 42.35 nm	424:440	404.67 ± 42.35 nm	424:440	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	15	theme	minimum	410:416	arg1	size					418:421	a minimum size	408:421	a minimum size (404.67 ± 42.35 nm)	408:441	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	3	16	theme	Cur	549:551	arg1	ratio					571:575	Cur: CS-Nano-ZnO mass ratio	549:575	Cur: CS-Nano-ZnO mass ratio of 5:5	549:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	5	17	theme	Kyoho	791:795	arg1	trial					817:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	3	18	theme	fiber	529:533	arg1	membrane					535:542	The composite fiber membrane	515:542	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5	515:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	5	19	theme	fresh-keeping	803:815	arg1	trial					817:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	5	20	theme	higher	925:930	arg1	rate					932:935	a higher rate	923:935	a higher rate of good fruit (60.25 ± 1.46 %)	923:966	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	5	20	theme	higher	925:930	arg1	%					965:965	60.25 ± 1.46 %	952:965	60.25 ± 1.46 %	952:965	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	3	21	theme	vapor	609:613	arg1	permeability					615:626	water vapor permeability	603:626	water vapor permeability	603:626	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	1	22	theme	Nanofibrous	110:120	arg1	membranes					132:140	Nanofibrous composite membranes	110:140	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur)	110:273	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	2	23	theme	prepared	383:390	arg1	CS-Nano-ZnO					392:402	the prepared CS-Nano-ZnO	379:402	the prepared CS-Nano-ZnO	379:402	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	0	24	theme	chitosan-nano	41:53	arg1	oxide					60:64	chitosan-nano zinc oxide	41:64	chitosan-nano zinc oxide	41:64	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	5	25	theme	good	906:909	arg1	quality					911:917	good quality	906:917	good quality	906:917	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	3	26	with	membrane	535:542	arg1	ratio					571:575	Cur: CS-Nano-ZnO mass ratio	549:575	Cur: CS-Nano-ZnO mass ratio of 5:5	549:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	3	27	theme	mass	566:569	arg1	ratio					571:575	Cur: CS-Nano-ZnO mass ratio	549:575	Cur: CS-Nano-ZnO mass ratio of 5:5	549:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	3	28	theme	best	598:601	arg1	permeability					615:626	water vapor permeability	603:626	water vapor permeability	603:626	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	5	29	theme	storage	985:991	arg1	12 days					974:980	12 days	974:980	12 days of storage	974:991	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	6	30	theme	shelf	998:1002	arg1	life					1004:1007	The shelf life	994:1007	The shelf life of grape	994:1016	The shelf life of grape was extended by at least 4 days.					
37119898	5	31	theme	composite	864:872	arg1	membrane					880:887	composite fiber membrane	864:887	composite fiber membrane	864:887	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	3	32	theme	water	603:607	arg1	permeability					615:626	water vapor permeability	603:626	water vapor permeability	603:626	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	1	33	theme	composite	122:130	arg1	membranes					132:140	Nanofibrous composite membranes	110:140	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur)	110:273	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	0	34	theme	zinc	55:58	arg1	oxide					60:64	chitosan-nano zinc oxide	41:64	chitosan-nano zinc oxide	41:64	Nanofibrous composite membranes based on chitosan-nano zinc oxide and curcumin for Kyoho grapes preservation.					
37119898	3	35	theme	CS-Nano-ZnO	554:564	arg1	ratio					571:575	Cur: CS-Nano-ZnO mass ratio	549:575	Cur: CS-Nano-ZnO mass ratio of 5:5	549:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	4	36	theme	inhibitory	665:674	arg1	rates					676:680	the inhibitory rates	661:680	the inhibitory rates against Escherichia coli and Staphylococcus aureus	661:731	Furthermore, the inhibitory rates against Escherichia coli and Staphylococcus aureus were 91.93 ± 2.07 % and 93.00 ± 0.83 %, respectively.					
37119898	4	36	theme	inhibitory	665:674	arg1	%					751:751	91.93 ± 2.07 %	738:751	91.93 ± 2.07 %	738:751	Furthermore, the inhibitory rates against Escherichia coli and Staphylococcus aureus were 91.93 ± 2.07 % and 93.00 ± 0.83 %, respectively.					
37119898	1	37	theme	ultrasonic	292:301	arg1	processing					303:312	ultrasonic processing	292:312	ultrasonic processing	292:312	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	38	theme	chitosan-nano	203:215	arg1	CS-Nano-ZnO					243:253	CS-Nano-ZnO	243:253	CS-Nano-ZnO	243:253	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	38	theme	chitosan-nano	203:215	arg1	nanoparticles					228:240	chitosan-nano zinc oxide nanoparticles	203:240	chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO)	203:254	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	5	39	theme	grape	797:801	arg1	trial					817:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial	787:821	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	5	40	theme	fiber	874:878	arg1	membrane					880:887	composite fiber membrane	864:887	composite fiber membrane	864:887	The Kyoho grape fresh-keeping trial revealed that grape berries wrapped with composite fiber membrane still maintained good quality and a higher rate of good fruit (60.25 ± 1.46 %) after 12 days of storage.					
37119898	1	41	theme	zinc	217:220	arg1	CS-Nano-ZnO					243:253	CS-Nano-ZnO	243:253	CS-Nano-ZnO	243:253	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	41	theme	zinc	217:220	arg1	nanoparticles					228:240	chitosan-nano zinc oxide nanoparticles	203:240	chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO)	203:254	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	2	42	theme	particle	467:474	arg1	distribution					481:492	a generally uniform particle size distribution	447:492	a generally uniform particle size distribution (PDI = 0.32 ± 0.10)	447:512	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	42	theme	particle	467:474	arg1	PDI = 0.32 ± 0.10					495:511	PDI = 0.32 ± 0.10	495:511	PDI = 0.32 ± 0.10	495:511	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	6	43	theme	grape	1012:1016	arg1	life					1004:1007	The shelf life	994:1007	The shelf life of grape	994:1016	The shelf life of grape was extended by at least 4 days.					
37119898	1	44	theme	polyvinyl	156:164	arg1	alcohol					166:172	polyvinyl alcohol	156:172	polyvinyl alcohol (PVA)	156:178	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	44	theme	polyvinyl	156:164	arg1	PVA					175:177	PVA	175:177	PVA	175:177	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	7	45	theme	food	1168:1171	arg1	packaging					1173:1181	food packaging	1168:1181	food packaging	1168:1181	Thus, nanofibrous composite membranes based on CS-Nano-ZnO and Cur was expected to be used as an active material for food packaging.					
37119898	1	46	theme	oxide	222:226	arg1	CS-Nano-ZnO					243:253	CS-Nano-ZnO	243:253	CS-Nano-ZnO	243:253	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	1	46	theme	oxide	222:226	arg1	nanoparticles					228:240	chitosan-nano zinc oxide nanoparticles	203:240	chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO)	203:254	Nanofibrous composite membranes consisting of polyvinyl alcohol (PVA), sodium alginate (SA), chitosan-nano zinc oxide nanoparticles (CS-Nano-ZnO) and curcumin (Cur) were prepared by ultrasonic processing and electrospinning.					
37119898	2	47	theme	uniform	459:465	arg1	distribution					481:492	a generally uniform particle size distribution	447:492	a generally uniform particle size distribution (PDI = 0.32 ± 0.10)	447:512	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	2	47	theme	uniform	459:465	arg1	PDI = 0.32 ± 0.10					495:511	PDI = 0.32 ± 0.10	495:511	PDI = 0.32 ± 0.10	495:511	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
37119898	3	48	theme	5:5	580:582	arg1	ratio					571:575	Cur: CS-Nano-ZnO mass ratio	549:575	Cur: CS-Nano-ZnO mass ratio of 5:5	549:582	The composite fiber membrane with Cur: CS-Nano-ZnO mass ratio of 5:5 exhibited the best water vapor permeability, strain and stress.					
37119898	2	49	theme	ultrasonic	344:353	arg1	power					355:359	the ultrasonic power	340:359	the ultrasonic power	340:359	When the ultrasonic power was set to 100 W, the prepared CS-Nano-ZnO had a minimum size (404.67 ± 42.35 nm) and a generally uniform particle size distribution (PDI = 0.32 ± 0.10).					
36855862	11	0	theme	millimeter-scale	1445:1460	arg1	ATPS					1462:1465	millimeter-scale ATPS	1445:1465	millimeter-scale ATPS	1445:1465	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	11	1	theme	10	1567:1568	arg1	mM					1570:1571	mM	1570:1571	mM	1570:1571	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	7	2	theme	fluorescein	828:838	arg1	FITC					856:859	FITC	856:859	FITC	856:859	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	2	theme	fluorescein	828:838	arg1	isothiocyanate					840:853	fluorescein isothiocyanate	828:853	fluorescein isothiocyanate (FITC)	828:860	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	2	theme	fluorescein	828:838	arg1	isolation					804:812	partitioning-induced isolation	783:812	partitioning-induced isolation	783:812	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	4	3	theme	two-phase	442:450	arg1	system					452:457	the aqueous two-phase system	430:457	the aqueous two-phase system (ATPS)	430:464	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	4	3	theme	two-phase	442:450	arg1	ATPS					460:463	ATPS	460:463	ATPS	460:463	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	4	theme	10	1431:1432	arg1	mM					1434:1435	mM	1434:1435	mM	1434:1435	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	5	theme	centimeter-scale	1294:1309	arg1	ATPS					1311:1314	centimeter-scale ATPS	1294:1314	centimeter-scale ATPS	1294:1314	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	2	6	theme	Conventional	175:186	arg1	labeling					188:195	Conventional labeling	175:195	Conventional labeling	175:195	Conventional labeling requires washing to remove the excess fluorescent labels and reduce the noise signals.					
36855862	8	7	theme	dextran	1073:1079	arg1	fractions					1030:1038	mass fractions	1025:1038	mass fractions	1025:1038	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	7	theme	dextran	1073:1079	arg1	weights					1013:1019	different molecular weights	993:1019	different molecular weights	993:1019	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	7	theme	dextran	1073:1079	arg1	concentrations					1127:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	9	8	theme	bioanalytical	1263:1275	arg1	applications					1277:1288	various bioanalytical applications	1255:1288	various bioanalytical applications	1255:1288	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
36855862	11	9	from	Da	1531:1532	arg1	PBS					1573:1575	10 mM PBS	1567:1575	10 mM PBS	1567:1575	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	7	10	theme	partitioning-induced	783:802	arg1	isothiocyanate					840:853	fluorescein isothiocyanate	828:853	fluorescein isothiocyanate (FITC)	828:860	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	10	theme	partitioning-induced	783:802	arg1	isolation					804:812	partitioning-induced isolation	783:812	partitioning-induced isolation	783:812	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	11	11	theme	wt	1515:1516	arg1	Da					1531:1532	15 wt % PEG 35,000 Da	1512:1532	15 wt % PEG 35,000 Da	1512:1532	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	4	12	theme	partitioning-induced	481:500	arg1	isolation					502:510	the partitioning-induced isolation	477:510	the partitioning-induced isolation of labeled analytes from background signals	477:554	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	2	13	theme	noise	269:273	arg1	signals					275:281	the noise signals	265:281	the noise signals	265:281	Conventional labeling requires washing to remove the excess fluorescent labels and reduce the noise signals.					
36855862	12	14	theme	analyte	1598:1604	arg1	dilutions					1606:1614	analyte dilutions	1598:1614	analyte dilutions	1598:1614	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	3	15	theme	specialized	333:343	arg1	equipment					345:353	specialized equipment	333:353	specialized equipment	333:353	These pretreatments are labor intensive and need specialized equipment, hindering portable applications in resource-limited areas.					
36855862	8	16	theme	polyethylene	1043:1054	arg1	PEG					1064:1066	PEG	1064:1066	PEG	1064:1066	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	16	theme	polyethylene	1043:1054	arg1	glycol					1056:1061	polyethylene glycol	1043:1061	polyethylene glycol (PEG)	1043:1067	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	11	17	theme	5	1538:1538	arg1	wt					1540:1541	wt	1540:1541	wt	1540:1541	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	11	18	from	ATPS	1462:1465	arg1	analyte					1472:1478	the analyte	1468:1478	the analyte	1468:1478	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	11	18	from	ATPS	1462:1465	arg1	enriched					1483:1490	enriched	1483:1490	enriched	1483:1490	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	1	19	theme	analytes	165:172	arg1	labeling					153:160	labeling	153:160	labeling of analytes	153:172	Most fluorescence-based bioanalytical applications need labeling of analytes.					
36855862	10	20	theme	optimized	1321:1329	arg1	ratios					1344:1349	the optimized distribution ratios	1317:1349	the optimized distribution ratios of IgG and FITC	1317:1365	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	20	theme	optimized	1321:1329	arg1	91.682					1371:1376	91.682	1371:1376	91.682	1371:1376	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	0	21	theme	Aqueous	71:77	arg1	System					89:94	Multiscaled Aqueous Two-Phase System	59:94	Multiscaled Aqueous Two-Phase System	59:94	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	3	22	theme	portable	366:373	arg1	applications					375:386	portable applications	366:386	portable applications in resource-limited areas	366:412	These pretreatments are labor intensive and need specialized equipment, hindering portable applications in resource-limited areas.					
36855862	6	23	theme	intrinsic	697:705	arg1	differences					716:726	intrinsic affinity differences	697:726	intrinsic affinity differences between analytes and excess labels	697:761	ATPS-based isolation is driven by intrinsic affinity differences between analytes and excess labels.					
36855862	8	24	theme	different	1085:1093	arg1	concentrations					1127:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	12	25	theme	analyte	1725:1731	arg1	0.982					1754:1758	0.982	1754:1758	0.982	1754:1758	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	12	25	theme	analyte	1725:1731	arg1	concentrations					1733:1746	the analyte concentrations	1721:1746	the analyte concentrations (R2 = 0.982)	1721:1759	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	4	26	theme	processing	570:579	arg1	steps					581:585	extra processing steps	564:585	extra processing steps	564:585	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	27	theme	IgG	1354:1356	arg1	ratios					1344:1349	the optimized distribution ratios	1317:1349	the optimized distribution ratios of IgG and FITC	1317:1365	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	27	theme	IgG	1354:1356	arg1	91.682					1371:1376	91.682	1371:1376	91.682	1371:1376	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	8	28	theme	saline	1114:1119	arg1	concentrations					1127:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	4	29	theme	analytes	523:530	arg1	isolation					502:510	the partitioning-induced isolation	477:510	the partitioning-induced isolation of labeled analytes from background signals	477:554	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	30	theme	distribution	1331:1342	arg1	ratios					1344:1349	the optimized distribution ratios	1317:1349	the optimized distribution ratios of IgG and FITC	1317:1365	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	30	theme	distribution	1331:1342	arg1	91.682					1371:1376	91.682	1371:1376	91.682	1371:1376	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	4	31	theme	background	537:546	arg1	signals					548:554	background signals	537:554	background signals	537:554	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	9	32	theme	operational	1168:1178	arg1	scales					1180:1185	Various operational scales	1160:1185	Various operational scales of our approach	1160:1201	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
36855862	0	33	theme	Partitioning-Induced	0:19	arg1	Isolation					21:29	Partitioning-Induced Isolation	0:29	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.	0:95	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	5	34	theme	high	642:645	arg1	concentrations					647:660	sufficiently high concentrations	629:660	sufficiently high concentrations	629:660	ATPS is formed by mixing two polymers at sufficiently high concentrations.					
36855862	1	35	theme	fluorescence-based	102:119	arg1	applications					135:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications need labeling of analytes.					
36855862	10	36	from	Da	1425:1426	arg1	PBS					1437:1439	10 mM PBS	1431:1439	10 mM PBS	1431:1439	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	11	37	theme	PEG	1520:1522	arg1	Da					1531:1532	15 wt % PEG 35,000 Da	1512:1532	15 wt % PEG 35,000 Da	1512:1532	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	7	38	theme	interfering	881:891	arg1	fluorophore					893:903	the interfering fluorophore	877:903	the interfering fluorophore	877:903	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	6	39	theme	excess	749:754	arg1	labels					756:761	excess labels	749:761	excess labels	749:761	ATPS-based isolation is driven by intrinsic affinity differences between analytes and excess labels.					
36855862	9	40	theme	approach	1194:1201	arg1	scales					1180:1185	Various operational scales	1160:1185	Various operational scales of our approach	1160:1201	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
36855862	8	41	theme	different	993:1001	arg1	weights					1013:1019	different molecular weights	993:1019	different molecular weights	993:1019	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	10	42	theme	dextran	1410:1416	arg1	Da					1425:1426	dextran 10,000 Da	1410:1426	dextran 10,000 Da	1410:1426	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	8	43	theme	mass	1025:1028	arg1	fractions					1030:1038	mass fractions	1025:1038	mass fractions	1025:1038	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	2	44	theme	excess	228:233	arg1	labels					247:252	the excess fluorescent labels	224:252	the excess fluorescent labels	224:252	Conventional labeling requires washing to remove the excess fluorescent labels and reduce the noise signals.					
36855862	6	45	theme	affinity	707:714	arg1	differences					716:726	intrinsic affinity differences	697:726	intrinsic affinity differences between analytes and excess labels	697:761	ATPS-based isolation is driven by intrinsic affinity differences between analytes and excess labels.					
36855862	9	46	theme	various	1255:1261	arg1	applications					1277:1288	various bioanalytical applications	1255:1288	various bioanalytical applications	1255:1288	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
36855862	8	47	theme	glycol	1056:1061	arg1	fractions					1030:1038	mass fractions	1025:1038	mass fractions	1025:1038	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	47	theme	glycol	1056:1061	arg1	weights					1013:1019	different molecular weights	993:1019	different molecular weights	993:1019	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	47	theme	glycol	1056:1061	arg1	concentrations					1127:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	different phosphate-buffered saline (PBS) concentrations	1085:1140	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	11	48	theme	mM	1570:1571	arg1	PBS					1573:1575	10 mM PBS	1567:1575	10 mM PBS	1567:1575	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	7	49	used	used	941:944	arg2	analyte					953:959	the analyte	949:959	the analyte	949:959	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	49	used	used	941:944	arg2	IgG					933:935	IgG	933:935	IgG	933:935	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	49	used	used	941:944	arg2	antibody					923:930	a monoclonal antibody	910:930	a monoclonal antibody (IgG)	910:936	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	4	50	from	signals	548:554	arg1	isolation					502:510	the partitioning-induced isolation	477:510	the partitioning-induced isolation of labeled analytes from background signals	477:554	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	51	theme	FITC	1362:1365	arg1	ratios					1344:1349	the optimized distribution ratios	1317:1349	the optimized distribution ratios of IgG and FITC	1317:1365	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	51	theme	FITC	1362:1365	arg1	91.682					1371:1376	91.682	1371:1376	91.682	1371:1376	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	4	52	theme	aqueous	434:440	arg1	system					452:457	the aqueous two-phase system	430:457	the aqueous two-phase system (ATPS)	430:464	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	4	52	theme	aqueous	434:440	arg1	ATPS					460:463	ATPS	460:463	ATPS	460:463	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	6	53	theme	ATPS-based	663:672	arg1	isolation					674:682	ATPS-based isolation	663:682	ATPS-based isolation	663:682	ATPS-based isolation is driven by intrinsic affinity differences between analytes and excess labels.					
36855862	12	54	theme	picoliter	1634:1642	arg1	droplets					1644:1651	picoliter droplets	1634:1651	picoliter droplets	1634:1651	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	7	55	theme	monoclonal	912:921	arg1	antibody					923:930	a monoclonal antibody	910:930	a monoclonal antibody (IgG)	910:936	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	55	theme	monoclonal	912:921	arg1	analyte					953:959	the analyte	949:959	the analyte	949:959	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	7	55	theme	monoclonal	912:921	arg1	IgG					933:935	IgG	933:935	IgG	933:935	To demonstrate the partitioning-induced isolation and analysis, fluorescein isothiocyanate (FITC) is selected as the interfering fluorophore, and a monoclonal antibody (IgG) is used as the analyte.					
36855862	4	56	theme	labeled	515:521	arg1	analytes					523:530	labeled analytes	515:530	labeled analytes	515:530	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	57	from	91.682	1371:1376	arg1	ATPS					1311:1314	centimeter-scale ATPS	1294:1314	centimeter-scale ATPS	1294:1314	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	10	58	theme	PEG	1394:1396	arg1	Da					1403:1404	PEG 6000 Da	1394:1404	PEG 6000 Da	1394:1404	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	11	59	from	enriched	1483:1490	arg1	ATPS					1462:1465	millimeter-scale ATPS	1445:1465	millimeter-scale ATPS	1445:1465	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	3	60	from	applications	375:386	arg1	areas					408:412	resource-limited areas	391:412	resource-limited areas	391:412	These pretreatments are labor intensive and need specialized equipment, hindering portable applications in resource-limited areas.					
36855862	11	61	theme	35,000	1524:1529	arg1	Da					1531:1532	15 wt % PEG 35,000 Da	1512:1532	15 wt % PEG 35,000 Da	1512:1532	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	0	62	theme	Two-Phase	79:87	arg1	System					89:94	Multiscaled Aqueous Two-Phase System	59:94	Multiscaled Aqueous Two-Phase System	59:94	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	11	63	theme	%	1543:1543	arg1	Da					1561:1562	5 wt % dextran 500,000 Da	1538:1562	5 wt % dextran 500,000 Da	1538:1562	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	11	64	from	Da	1561:1562	arg1	PBS					1573:1575	10 mM PBS	1567:1575	10 mM PBS	1567:1575	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	12	65	theme	microscale	1581:1590	arg1	ATPS					1592:1595	microscale ATPS	1581:1595	microscale ATPS	1581:1595	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	3	66	theme	resource-limited	391:406	arg1	areas					408:412	resource-limited areas	391:412	resource-limited areas	391:412	These pretreatments are labor intensive and need specialized equipment, hindering portable applications in resource-limited areas.					
36855862	4	67	theme	extra	564:568	arg1	steps					581:585	extra processing steps	564:585	extra processing steps	564:585	Herein, we use the aqueous two-phase system (ATPS) to realize the partitioning-induced isolation of labeled analytes from background signals without extra processing steps.					
36855862	10	68	from	Da	1403:1404	arg1	PBS					1437:1439	10 mM PBS	1431:1439	10 mM PBS	1431:1439	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	11	69	theme	dextran	1545:1551	arg1	Da					1561:1562	5 wt % dextran 500,000 Da	1538:1562	5 wt % dextran 500,000 Da	1538:1562	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	8	70	theme	phosphate-buffered	1095:1112	arg1	saline					1114:1119	phosphate-buffered saline	1095:1119	different phosphate-buffered saline (PBS) concentrations	1085:1140	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	8	70	theme	phosphate-buffered	1095:1112	arg1	PBS					1122:1124	PBS	1122:1124	PBS	1122:1124	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	11	71	theme	wt	1540:1541	arg1	Da					1561:1562	5 wt % dextran 500,000 Da	1538:1562	5 wt % dextran 500,000 Da	1538:1562	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	12	72	theme	measured	1662:1669	arg1	fluorescence					1671:1682	the measured fluorescence	1658:1682	the measured fluorescence	1658:1682	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	9	73	theme	Various	1160:1166	arg1	scales					1180:1185	Various operational scales	1160:1185	Various operational scales of our approach	1160:1201	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
36855862	1	74	theme	Most	97:100	arg1	applications					135:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications need labeling of analytes.					
36855862	11	75	theme	%	1518:1518	arg1	Da					1531:1532	15 wt % PEG 35,000 Da	1512:1532	15 wt % PEG 35,000 Da	1512:1532	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	0	76	theme	Analyte	34:40	arg1	Isolation					21:29	Partitioning-Induced Isolation	0:29	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.	0:95	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	1	77	theme	bioanalytical	121:133	arg1	applications					135:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications	97:146	Most fluorescence-based bioanalytical applications need labeling of analytes.					
36855862	12	78	dep	intensities	1684:1694	arg1	correlated					1705:1714	correlated	1705:1714	intensities linearly correlated with the analyte concentrations (R2 = 0.982)	1684:1759	In microscale ATPS, analyte dilutions are isolated into picoliter droplets, and the measured fluorescence intensities linearly correlated with the analyte concentrations (R2 = 0.982).					
36855862	11	79	theme	15	1512:1513	arg1	wt					1515:1516	wt	1515:1516	wt	1515:1516	In millimeter-scale ATPS, the analyte is enriched to 6.067 fold using 15 wt % PEG 35,000 Da and 5 wt % dextran 500,000 Da in 10 mM PBS.					
36855862	0	80	theme	Analysis	46:53	arg1	Isolation					21:29	Partitioning-Induced Isolation	0:29	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.	0:95	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	8	81	theme	ATPS	974:977	arg1	compositions					979:990	ATPS compositions	974:990	ATPS compositions	974:990	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	0	82	theme	Multiscaled	59:69	arg1	System					89:94	Multiscaled Aqueous Two-Phase System	59:94	Multiscaled Aqueous Two-Phase System	59:94	Partitioning-Induced Isolation of Analyte and Analysis via Multiscaled Aqueous Two-Phase System.					
36855862	8	83	theme	molecular	1003:1011	arg1	weights					1013:1019	different molecular weights	993:1019	different molecular weights	993:1019	To optimize ATPS compositions, different molecular weights and mass fractions of polyethylene glycol (PEG) and dextran and different phosphate-buffered saline (PBS) concentrations are investigated.					
36855862	2	84	theme	fluorescent	235:245	arg1	labels					247:252	the excess fluorescent labels	224:252	the excess fluorescent labels	224:252	Conventional labeling requires washing to remove the excess fluorescent labels and reduce the noise signals.					
36855862	10	85	theme	mM	1434:1435	arg1	PBS					1437:1439	10 mM PBS	1431:1439	10 mM PBS	1431:1439	In centimeter-scale ATPS, the optimized distribution ratios of IgG and FITC are 91.682 and 0.998 using PEG 6000 Da and dextran 10,000 Da in 10 mM PBS.					
36855862	9	86	with	compatibility	1236:1248	arg1	applications					1277:1288	various bioanalytical applications	1255:1288	various bioanalytical applications	1255:1288	Various operational scales of our approach are demonstrated, suggesting its compatibility with various bioanalytical applications.					
35879284	3	0	theme	genetic	661:667	arg1	elements					669:676	functional genetic elements	650:676	functional genetic elements	650:676	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	5	1	theme	betaine	978:984	arg1	biosynthesis					986:997	betaine biosynthesis	978:997	betaine biosynthesis	978:997	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	3	2	from	genus	509:513	arg1	KMC					518:520	KMC	518:520	KMC	518:520	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	5	3	theme	polyamines	1000:1009	arg1	biosynthesis					1011:1022	polyamines biosynthesis	1000:1022	polyamines biosynthesis	1000:1022	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	0	4	from	Genomes	21:27	arg1	Kombucha					54:61	Kombucha	54:61	Kombucha	54:61	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	1	5	theme	health	269:274	arg1	benefits					276:283	health benefits	269:283	health benefits	269:283	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	5	6	theme	specific	884:891	arg1	features					904:911	specific functional features	884:911	specific functional features	884:911	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	6	7	theme	space	1431:1435	arg1	travelers					1437:1445	space travelers	1431:1445	space travelers	1431:1445	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	5	8	theme	important	1173:1181	arg1	roles					1183:1187	important roles	1173:1187	important roles	1173:1187	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	6	9	theme	extraterrestrial	1338:1353	arg1	stress					1355:1360	the extraterrestrial stress	1334:1360	the extraterrestrial stress	1334:1360	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	5	10	theme	TA	1097:1098	arg1	system					1101:1106	type II toxin-antitoxin (TA) system	1072:1106	type II toxin-antitoxin (TA) system	1072:1106	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	0	11	theme	Extraterrestrial	128:143	arg1	Stresses					145:152	Extraterrestrial Stresses	128:152	Extraterrestrial Stresses	128:152	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	3	12	theme	predominant	497:507	arg1	genomes					446:452	metagenome-assembled genomes	425:452	metagenome-assembled genomes (MAGs)	425:459	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	12	theme	predominant	497:507	arg1	genus					509:513	a predominant genus	495:513	a predominant genus in KMC	495:520	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	6	13	theme	KMC	1423:1425	arg1	composition					1408:1418	minimal microbial composition	1390:1418	minimal microbial composition of KMC for space travelers	1390:1445	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	5	14	theme	K.	779:780	arg1	hansenii					848:855	K. hansenii	845:855	K. hansenii	845:855	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	14	theme	K.	779:780	arg1	keystone					862:869	keystone	862:869	keystone	862:869	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	14	theme	K.	779:780	arg1	MAG					792:794	K. oboediens MAG	779:794	K. oboediens MAG	779:794	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	6	15	theme	microbial	1398:1406	arg1	composition					1408:1418	minimal microbial composition	1390:1418	minimal microbial composition of KMC for space travelers	1390:1445	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	0	16	from	Kombucha	54:61	arg1	Genomes					21:27	Metagenome-Assembled Genomes	0:27	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions	0:93	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	4	17	dep	K.	737:738	arg1	oboediens					740:748	K. oboediens	737:748	K. oboediens	737:748	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	5	18	theme	type	1072:1075	arg1	system					1101:1106	type II toxin-antitoxin (TA) system	1072:1106	type II toxin-antitoxin (TA) system	1072:1106	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	2	19	theme	conditions	371:380	arg1	effect					351:356	the effect	347:356	the effect of Mars-like conditions on the KMC	347:391	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	2	19	theme	conditions	371:380	arg1	part					289:292	part	289:292	part of the BIOlogy and Mars EXperiment (BIOMEX) project	289:344	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	0	20	theme	Metagenome-Assembled	0:19	arg1	Genomes					21:27	Metagenome-Assembled Genomes	0:27	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions	0:93	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	2	21	theme	Mars	313:316	arg1	project					338:344	the BIOlogy and Mars EXperiment (BIOMEX) project	297:344	the BIOlogy and Mars EXperiment (BIOMEX) project	297:344	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	2	21	theme	Mars	313:316	arg1	BIOMEX					330:335	BIOMEX	330:335	BIOMEX	330:335	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	3	22	from	roles	543:547	arg1	KMC					556:558	the KMC	552:558	the KMC after exposure to Mars-like conditions (outside the International Space Station)	552:639	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	2	23	theme	Mars-like	361:369	arg1	conditions					371:380	Mars-like conditions	361:380	Mars-like conditions	361:380	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	0	24	theme	Komagataeibacter	32:47	arg1	Genomes					21:27	Metagenome-Assembled Genomes	0:27	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions	0:93	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	2	25	from	effect	351:356	arg1	KMC					389:391	the KMC	385:391	the KMC	385:391	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	6	26	theme	minimal	1390:1396	arg1	composition					1408:1418	minimal microbial composition	1390:1418	minimal microbial composition of KMC for space travelers	1390:1445	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	1	27	theme	acid	214:217	arg1	bacteria					219:226	acetic acid bacteria	207:226	acetic acid bacteria	207:226	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	5	28	theme	K.	845:846	arg1	hansenii					848:855	K. hansenii	845:855	K. hansenii	845:855	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	28	theme	K.	845:846	arg1	keystone					862:869	keystone	862:869	keystone	862:869	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	28	theme	K.	845:846	arg1	MAG					792:794	K. oboediens MAG	779:794	K. oboediens MAG	779:794	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	2	29	theme	BIOlogy	301:307	arg1	project					338:344	the BIOlogy and Mars EXperiment (BIOMEX) project	297:344	the BIOlogy and Mars EXperiment (BIOMEX) project	297:344	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	2	29	theme	BIOlogy	301:307	arg1	BIOMEX					330:335	BIOMEX	330:335	BIOMEX	330:335	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	5	30	theme	oboediens	782:790	arg1	hansenii					848:855	K. hansenii	845:855	K. hansenii	845:855	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	30	theme	oboediens	782:790	arg1	keystone					862:869	keystone	862:869	keystone	862:869	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	30	theme	oboediens	782:790	arg1	MAG					792:794	K. oboediens MAG	779:794	K. oboediens MAG	779:794	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	3	31	theme	Komagataeibacter	468:483	arg1	genomes					446:452	metagenome-assembled genomes	425:452	metagenome-assembled genomes (MAGs)	425:459	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	31	theme	Komagataeibacter	468:483	arg1	genus					509:513	a predominant genus	495:513	a predominant genus in KMC	495:520	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	31	theme	Komagataeibacter	468:483	arg1	MAGs					455:458	MAGs	455:458	MAGs	455:458	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	1	32	theme	acetic	207:212	arg1	bacteria					219:226	acetic acid bacteria	207:226	acetic acid bacteria	207:226	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	3	33	theme	metagenome-assembled	425:444	arg1	genomes					446:452	metagenome-assembled genomes	425:452	metagenome-assembled genomes (MAGs)	425:459	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	33	theme	metagenome-assembled	425:444	arg1	genus					509:513	a predominant genus	495:513	a predominant genus in KMC	495:520	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	33	theme	metagenome-assembled	425:444	arg1	MAGs					455:458	MAGs	455:458	MAGs	455:458	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	5	34	with	KMCs	874:877	arg1	features					904:911	specific functional features	884:911	specific functional features	884:911	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	35	theme	toxin-antitoxin	1080:1094	arg1	system					1101:1106	type II toxin-antitoxin (TA) system	1072:1106	type II toxin-antitoxin (TA) system	1072:1106	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	36	theme	related	957:963	arg1	genes					951:955	(iii) genes	945:955	(iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production	945:1160	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	37	dep	keystone	862:869	arg1	i					776:776	i	776:776	i	776:776	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	37	dep	keystone	862:869	arg1	tolerate					916:923	tolerate	916:923	to tolerate extreme stress	913:938	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	37	dep	keystone	862:869	arg1	complex					814:820	complex	814:820	complex	814:820	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	37	dep	keystone	862:869	arg1	play					1168:1171	play	1168:1171	could play important roles in the resilience of KMC after exposure to Mars-like stress	1162:1247	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	37	dep	keystone	862:869	arg1	ii					841:842	ii	841:842	ii	841:842	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	38	theme	sulfate-sulfur	1025:1038	arg1	pathway					1053:1059	sulfate-sulfur assimilation pathway	1025:1059	sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system	1025:1106	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	39	theme	extreme	925:931	arg1	stress					933:938	extreme stress	925:938	extreme stress	925:938	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	40	theme	Mars-like	1232:1240	arg1	stress					1242:1247	Mars-like stress	1232:1247	Mars-like stress	1232:1247	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	2	41	theme	project	338:344	arg1	effect					351:356	the effect	347:356	the effect of Mars-like conditions on the KMC	347:391	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	2	41	theme	project	338:344	arg1	part					289:292	part	289:292	part of the BIOlogy and Mars EXperiment (BIOMEX) project	289:344	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	5	42	theme	assimilation	1040:1051	arg1	pathway					1053:1059	sulfate-sulfur assimilation pathway	1025:1059	sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system	1025:1106	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	2	43	dep	BIOlogy	301:307	arg1	the					297:299	the	297:299	the	297:299	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	2	43	dep	BIOlogy	301:307	arg1	EXperiment					318:327	EXperiment	318:327	EXperiment	318:327	As part of the BIOlogy and Mars EXperiment (BIOMEX) project, the effect of Mars-like conditions on the KMC was analyzed.					
35879284	1	44	theme	Kombucha	155:162	arg1	KMC					187:189	KMC	187:189	KMC	187:189	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	1	44	theme	Kombucha	155:162	arg1	community					176:184	Kombucha mutualistic community	155:184	Kombucha mutualistic community (KMC)	155:190	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	3	45	theme	International	612:624	arg1	Space					626:630	International Space	612:630	the International Space Station	608:638	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	3	46	theme	Mars-like	578:586	arg1	conditions					588:597	Mars-like conditions	578:597	Mars-like conditions	578:597	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	1	47	theme	mutualistic	164:174	arg1	KMC					187:189	KMC	187:189	KMC	187:189	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	1	47	theme	mutualistic	164:174	arg1	community					176:184	Kombucha mutualistic community	155:184	Kombucha mutualistic community (KMC)	155:190	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	4	48	dep	MAGs	700:703	arg1	K.					737:738	K.	737:738	K.	737:738	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	4	48	dep	MAGs	700:703	arg1	K.					706:707	K.	706:707	K.	706:707	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	4	48	dep	MAGs	700:703	arg1	K.					719:720	K.	719:720	K.	719:720	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	4	48	dep	MAGs	700:703	arg1	MAGs					700:703	three MAGs	694:703	three MAGs: K. hansenii, K. rhaeticus, and K. oboediens	694:748	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	3	49	theme	Space	626:630	arg1	Station					632:638	the International Space Station	608:638	the International Space Station	608:638	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	5	50	theme	functional	893:902	arg1	features					904:911	specific functional features	884:911	specific functional features	884:911	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	51	theme	KMC	1210:1212	arg1	resilience					1196:1205	the resilience	1192:1205	the resilience of KMC after exposure to Mars-like stress	1192:1247	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	52	theme	cellulose	1141:1149	arg1	production					1151:1160	cellulose production	1141:1160	cellulose production	1141:1160	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	1	53	theme	fermented	250:258	arg1	tea					260:262	fermented tea	250:262	fermented tea	250:262	Kombucha mutualistic community (KMC) is composed by acetic acid bacteria and yeasts, producing fermented tea with health benefits.					
35879284	0	54	theme	Mars-Like	74:82	arg1	Conditions					84:93	Mars-Like Conditions	74:93	Mars-Like Conditions	74:93	Metagenome-Assembled Genomes of Komagataeibacter from Kombucha Exposed to Mars-Like Conditions Reveal the Secrets in Tolerating Extraterrestrial Stresses.					
35879284	3	55	theme	functional	650:659	arg1	elements					669:676	functional genetic elements	650:676	functional genetic elements	650:676	Here, we analyzed metagenome-assembled genomes (MAGs) of the Komagataeibacter, which is a predominant genus in KMC, to understand their roles in the KMC after exposure to Mars-like conditions (outside the International Space Station) based on functional genetic elements.					
35879284	6	56	theme	potential	1272:1280	arg1	mechanisms					1282:1291	the potential mechanisms	1268:1291	the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers	1268:1445	Our findings show the potential mechanisms through which Komagataeibacter tolerates the extraterrestrial stress and will help to understand minimal microbial composition of KMC for space travelers.					
35879284	4	57	dep	K.	719:720	arg1	rhaeticus					722:730	K. rhaeticus	719:730	K. rhaeticus	719:730	We constructed three MAGs: K. hansenii, K. rhaeticus, and K. oboediens.					
35879284	5	58	theme	sensing	1116:1122	arg1	system					1129:1134	quorum sensing (QS) system	1109:1134	quorum sensing (QS) system	1109:1134	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	59	theme	quorum	1109:1114	arg1	QS					1125:1126	QS	1125:1126	QS	1125:1126	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
35879284	5	59	theme	quorum	1109:1114	arg1	sensing					1116:1122	quorum sensing	1109:1122	quorum sensing (QS) system	1109:1134	Our results showed that (i) K. oboediens MAG functionally more complex than K. hansenii, (ii) K. hansenii is a keystone in KMCs with specific functional features to tolerate extreme stress, and (iii) genes related to the PPDK, betaine biosynthesis, polyamines biosynthesis, sulfate-sulfur assimilation pathway as well as type II toxin-antitoxin (TA) system, quorum sensing (QS) system, and cellulose production could play important roles in the resilience of KMC after exposure to Mars-like stress.					
36270465	12	0	theme	quality	1751:1757	arg1	attributes					1759:1768	quality attributes	1751:1768	quality attributes of filler binders	1751:1786	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	6	1	attach	derived	959:965	arg1	literature					972:981	literature	972:981	literature	972:981	The model variables were derived from literature and calibrated with data.					
36270465	6	1	attach	derived	959:965	arg2	variables					944:952	The model variables	934:952	The model variables	934:952	The model variables were derived from literature and calibrated with data.					
36270465	7	2	theme	strong	1047:1052	arg1	r2 = 0.982					1067:1076	r2 = 0.982	1067:1076	r2 = 0.982	1067:1076	After optimization, the model shows a strong correlation (r2 = 0.982) between measured and predicted disintegration times.					
36270465	7	2	theme	strong	1047:1052	arg1	correlation					1054:1064	a strong correlation	1045:1064	a strong correlation (r2 = 0.982) between measured and predicted disintegration times	1045:1129	After optimization, the model shows a strong correlation (r2 = 0.982) between measured and predicted disintegration times.					
36270465	2	3	theme	lactose	307:313	arg1	properties					315:324	lactose properties	307:324	lactose properties	307:324	The current research aims to model the impact of lactose properties on disintegration time.					
36270465	1	4	theme	disintegration	221:234	arg1	behavior					236:243	the disintegration behavior	217:243	the disintegration behavior of a tablet	217:255	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	3	5	theme	parameters	450:459	arg1	impact					374:379	the impact	370:379	the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration	370:477	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	9	6	theme	tablet	1369:1374	arg1	disintegration					1376:1389	faster tablet disintegration	1362:1389	faster tablet disintegration	1362:1389	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	8	7	theme	size	1219:1222	arg1	distribution					1224:1235	the pore size distribution	1210:1235	the pore size distribution	1210:1235	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	2	8	from	impact	297:302	arg1	time					344:347	disintegration time	329:347	disintegration time	329:347	The current research aims to model the impact of lactose properties on disintegration time.					
36270465	4	9	theme	5 	619:620	arg1	%					621:621	%	621:621	%	621:621	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	1	10	theme	raw	150:152	arg1	properties					163:172	the raw material properties	146:172	the raw material properties of filler excipients	146:193	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	4	11	theme	w/w	622:624	arg1	sodium					637:642	5 %w/w diclofenac sodium	619:642	5 %w/w diclofenac sodium	619:642	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	10	12	theme	direct	1549:1554	arg1	driver					1556:1561	a direct driver	1547:1561	a direct driver for disintegration	1547:1580	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	10	12	theme	direct	1549:1554	arg1	strength					1516:1523	Tablet tensile strength	1501:1523	Tablet tensile strength	1501:1523	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	13	13	theme	formulation	1908:1918	arg1	development					1920:1930	quality-by-design formulation development	1890:1930	quality-by-design formulation development	1890:1930	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	5	14	theme	potential	800:808	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	14	theme	potential	800:808	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	14	theme	potential	800:808	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	14	theme	potential	800:808	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	14	theme	potential	800:808	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	12	15	theme	obtained	1695:1702	arg1	insights					1704:1711	The obtained insights	1691:1711	The obtained insights	1691:1711	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	2	16	theme	current	262:268	arg1	research					270:277	The current research	258:277	The current research	258:277	The current research aims to model the impact of lactose properties on disintegration time.					
36270465	1	17	theme	filler	177:182	arg1	excipients					184:193	filler excipients	177:193	filler excipients	177:193	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	8	18	theme	investigated	1142:1153	arg1	variables					1155:1163	all investigated variables	1138:1163	all investigated variables	1138:1163	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	8	19	theme	pore	1214:1217	arg1	distribution					1224:1235	the pore size distribution	1210:1235	the pore size distribution	1210:1235	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	0	20	from	study	58:62	arg1	polymorphism					80:91	polymorphism	80:91	polymorphism	80:91	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	0	20	from	study	58:62	arg1	porosity					67:74	porosity	67:74	porosity	67:74	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	4	21	theme	w/w	648:650	arg1	stearate					662:669	1 %w/w magnesium stearate	645:669	1 %w/w magnesium stearate	645:669	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	1	22	contain	have	199:202	arg1	properties					163:172	the raw material properties	146:172	the raw material properties of filler excipients	146:193	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	1	22	contain	have	199:202	arg2	impact					207:212	an impact	204:212	an impact on the disintegration behavior of a tablet	204:255	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	9	23	theme	lactose	1436:1442	arg1	monohydrate					1444:1454	lactose monohydrate	1436:1454	lactose monohydrate compared to anhydrous and amorphous lactose	1436:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	9	24	theme	monohydrate	1444:1454	arg1	rate					1428:1431	the slower dissolution rate	1405:1431	the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose	1405:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	4	25	theme	1 	645:646	arg1	%					647:647	%	647:647	%	647:647	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	9	26	theme	amorphous	1482:1490	arg1	lactose					1492:1498	amorphous lactose	1482:1498	amorphous lactose	1482:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	13	27	used	used	1861:1864	arg2	study					1838:1842	This study	1833:1842	This study	1833:1842	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	13	27	used	used	1861:1864	arg2	point					1880:1884	a starting point	1869:1884	a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration	1869:2009	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	3	28	theme	lactose	384:390	arg1	polymorphism					392:403	lactose polymorphism	384:403	lactose polymorphism	384:403	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	4	29	theme	2 	675:676	arg1	%					677:677	%	677:677	%	677:677	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	7	30	theme	predicted	1100:1108	arg1	times					1125:1129	predicted disintegration times	1100:1129	predicted disintegration times	1100:1129	After optimization, the model shows a strong correlation (r2 = 0.982) between measured and predicted disintegration times.					
36270465	4	31	theme	w/w	678:680	arg1	sodium					697:702	2 %w/w croscarmellose sodium	675:702	2 %w/w croscarmellose sodium	675:702	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	3	32	theme	tensile	413:419	arg1	strength					421:428	tablet tensile strength	406:428	tablet tensile strength	406:428	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	12	33	theme	disintegration	1817:1830	arg1	prediction					1796:1805	the prediction	1792:1805	the prediction of tablet disintegration	1792:1830	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	5	34	theme	pore	878:881	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	34	theme	pore	878:881	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	34	theme	pore	878:881	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	34	theme	pore	878:881	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	34	theme	pore	878:881	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	4	35	theme	different	512:520	arg1	qualities					530:538	Six different lactose qualities	508:538	Six different lactose qualities	508:538	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	11	36	theme	tablet	1647:1652	arg1	strength					1662:1669	tablet tensile strength	1647:1669	tablet tensile strength	1647:1669	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	8	37	theme	polymorphic	1170:1180	arg1	composition					1182:1192	the polymorphic composition	1166:1192	the polymorphic composition of lactose	1166:1203	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	0	38	theme	type	22:25	arg1	impact					4:9	The impact	0:9	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.	0:92	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	12	39	theme	filler	1773:1778	arg1	binders					1780:1786	filler binders	1773:1786	filler binders	1773:1786	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	3	40	theme	first	358:362	arg1	time					364:367	the first time	354:367	the first time	354:367	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	13	41	theme	tablet	1989:1994	arg1	disintegration					1996:2009	tablet disintegration	1989:2009	tablet disintegration	1989:2009	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	3	42	theme	pore	435:438	arg1	parameters					450:459	pore structure parameters	435:459	pore structure parameters	435:459	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	9	43	from	tablets	1345:1351	arg1	concentration					1305:1317	A higher concentration	1296:1317	A higher concentration of lactose monohydrate in tablets	1296:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	9	44	theme	lactose	1322:1328	arg1	monohydrate					1330:1340	lactose monohydrate	1322:1340	lactose monohydrate in tablets	1322:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	9	45	from	monohydrate	1330:1340	arg1	tablets					1345:1351	tablets	1345:1351	tablets	1345:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	5	46	theme	tensile	916:922	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	46	theme	tensile	916:922	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	46	theme	tensile	916:922	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	46	theme	tensile	916:922	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	46	theme	tensile	916:922	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	10	47	theme	tensile	1508:1514	arg1	driver					1556:1561	a direct driver	1547:1561	a direct driver for disintegration	1547:1580	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	10	47	theme	tensile	1508:1514	arg1	strength					1516:1523	Tablet tensile strength	1501:1523	Tablet tensile strength	1501:1523	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	13	48	theme	mechanistic	1959:1969	arg1	models					1971:1976	mechanistic models	1959:1976	mechanistic models	1959:1976	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	2	49	theme	disintegration	329:342	arg1	time					344:347	disintegration time	329:347	disintegration time	329:347	The current research aims to model the impact of lactose properties on disintegration time.					
36270465	12	50	theme	attributes	1759:1768	arg1	importance					1737:1746	the importance	1733:1746	the importance of quality attributes of filler binders for the prediction of tablet disintegration	1733:1830	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	4	51	theme	different	571:579	arg1	fractions					587:595	different solid fractions	571:595	different solid fractions	571:595	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	11	52	theme	size	1601:1604	arg1	driver					1631:1636	a mutual driver	1622:1636	a mutual driver for both tablet tensile strength and disintegration	1622:1688	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	11	52	theme	size	1601:1604	arg1	distribution					1606:1617	the pore size distribution	1592:1617	the pore size distribution	1592:1617	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	2	53	theme	properties	315:324	arg1	impact					297:302	the impact	293:302	the impact of lactose properties on disintegration time	293:347	The current research aims to model the impact of lactose properties on disintegration time.					
36270465	9	54	theme	faster	1362:1367	arg1	disintegration					1376:1389	faster tablet disintegration	1362:1389	faster tablet disintegration	1362:1389	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	11	55	theme	mutual	1624:1629	arg1	driver					1631:1636	a mutual driver	1622:1636	a mutual driver for both tablet tensile strength and disintegration	1622:1688	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	11	55	theme	mutual	1624:1629	arg1	distribution					1606:1617	the pore size distribution	1592:1617	the pore size distribution	1592:1617	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	13	56	theme	quality-by-design	1890:1906	arg1	development					1920:1930	quality-by-design formulation development	1890:1930	quality-by-design formulation development	1890:1930	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	1	57	theme	material	154:161	arg1	properties					163:172	the raw material properties	146:172	the raw material properties of filler excipients	146:193	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	4	58	theme	%	621:621	arg1	sodium					637:642	5 %w/w diclofenac sodium	619:642	5 %w/w diclofenac sodium	619:642	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	9	59	theme	slower	1409:1414	arg1	rate					1428:1431	the slower dissolution rate	1405:1431	the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose	1405:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	4	60	theme	fractions	587:595	arg1	tablets					560:566	tablets	560:566	tablets of different solid fractions	560:595	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	5	61	theme	disintegration	770:783	arg1	time					785:788	the disintegration time	766:788	the disintegration time	766:788	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	1	62	from	impact	207:212	arg1	behavior					236:243	the disintegration behavior	217:243	the disintegration behavior of a tablet	217:255	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	4	63	theme	%	647:647	arg1	stearate					662:669	1 %w/w magnesium stearate	645:669	1 %w/w magnesium stearate	645:669	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	5	64	theme	lactose	855:861	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	64	theme	lactose	855:861	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	64	theme	lactose	855:861	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	64	theme	lactose	855:861	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	64	theme	lactose	855:861	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	9	65	dep	leads	1353:1357	arg1	explained					1392:1400	explained	1392:1400	explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose	1392:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	4	66	theme	magnesium	652:660	arg1	stearate					662:669	1 %w/w magnesium stearate	645:669	1 %w/w magnesium stearate	645:669	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	13	67	theme	starting	1871:1878	arg1	study					1838:1842	This study	1833:1842	This study	1833:1842	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	13	67	theme	starting	1871:1878	arg1	point					1880:1884	a starting point	1869:1884	a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration	1869:2009	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
36270465	0	68	theme	integral	49:56	arg1	study					58:62	An integral study	46:62	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.	0:92	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	6	69	theme	model	938:942	arg1	variables					944:952	The model variables	934:952	The model variables	934:952	The model variables were derived from literature and calibrated with data.					
36270465	4	70	theme	diclofenac	626:635	arg1	sodium					637:642	5 %w/w diclofenac sodium	619:642	5 %w/w diclofenac sodium	619:642	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	9	71	from	concentration	1305:1317	arg1	tablets					1345:1351	tablets	1345:1351	tablets	1345:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	5	72	theme	polymorphic	824:834	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	72	theme	polymorphic	824:834	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	72	theme	polymorphic	824:834	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	72	theme	polymorphic	824:834	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	72	theme	polymorphic	824:834	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	0	73	from	impact	4:9	arg1	disintegration					30:43	disintegration	30:43	disintegration	30:43	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	5	74	theme	size	883:886	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	74	theme	size	883:886	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	74	theme	size	883:886	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	74	theme	size	883:886	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	74	theme	size	883:886	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	8	75	theme	tablet	1268:1273	arg1	disintegration					1275:1288	tablet disintegration	1268:1288	tablet disintegration	1268:1288	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	4	76	theme	croscarmellose	682:695	arg1	sodium					697:702	2 %w/w croscarmellose sodium	675:702	2 %w/w croscarmellose sodium	675:702	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	7	77	theme	disintegration	1110:1123	arg1	times					1125:1129	predicted disintegration times	1100:1129	predicted disintegration times	1100:1129	After optimization, the model shows a strong correlation (r2 = 0.982) between measured and predicted disintegration times.					
36270465	8	78	theme	lactose	1197:1203	arg1	composition					1182:1192	the polymorphic composition	1166:1192	the polymorphic composition of lactose	1166:1203	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	8	78	theme	lactose	1197:1203	arg1	distribution					1224:1235	the pore size distribution	1210:1235	the pore size distribution	1210:1235	Among all investigated variables, the polymorphic composition of lactose, and the pore size distribution have been identified to affect tablet disintegration most.					
36270465	3	79	theme	polymorphism	392:403	arg1	impact					374:379	the impact	370:379	the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration	370:477	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	12	80	from	guidance	1721:1728	arg1	importance					1737:1746	the importance	1733:1746	the importance of quality attributes of filler binders for the prediction of tablet disintegration	1733:1830	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	0	81	theme	lactose	14:20	arg1	type					22:25	lactose type	14:25	lactose type	14:25	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	1	82	theme	tablet	250:255	arg1	behavior					236:243	the disintegration behavior	217:243	the disintegration behavior of a tablet	217:255	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	4	83	theme	lactose	522:528	arg1	qualities					530:538	Six different lactose qualities	508:538	Six different lactose qualities	508:538	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	4	84	theme	%	677:677	arg1	sodium					697:702	2 %w/w croscarmellose sodium	675:702	2 %w/w croscarmellose sodium	675:702	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	3	85	theme	strength	421:428	arg1	impact					374:379	the impact	370:379	the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration	370:477	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	5	86	theme	linear	707:712	arg1	built					724:728	built	724:728	built	724:728	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	86	theme	linear	707:712	arg1	model					714:718	A linear model	705:718	A linear model	705:718	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	1	87	theme	excipients	184:193	arg1	properties					163:172	the raw material properties	146:172	the raw material properties of filler excipients	146:193	Besides factors such as disintegrant and lubricant, the raw material properties of filler excipients can have an impact on the disintegration behavior of a tablet.					
36270465	3	88	theme	tablet	406:411	arg1	strength					421:428	tablet tensile strength	406:428	tablet tensile strength	406:428	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	9	89	theme	higher	1298:1303	arg1	concentration					1305:1317	A higher concentration	1296:1317	A higher concentration of lactose monohydrate in tablets	1296:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	9	90	theme	dissolution	1416:1426	arg1	rate					1428:1431	the slower dissolution rate	1405:1431	the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose	1405:1498	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	4	91	with	formulation	602:612	arg1	sodium					697:702	2 %w/w croscarmellose sodium	675:702	2 %w/w croscarmellose sodium	675:702	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	4	91	with	formulation	602:612	arg1	sodium					637:642	5 %w/w diclofenac sodium	619:642	5 %w/w diclofenac sodium	619:642	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	4	91	with	formulation	602:612	arg1	stearate					662:669	1 %w/w magnesium stearate	645:669	1 %w/w magnesium stearate	645:669	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	3	92	theme	structure	440:448	arg1	parameters					450:459	pore structure parameters	435:459	pore structure parameters	435:459	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	12	93	theme	tablet	1810:1815	arg1	disintegration					1817:1830	tablet disintegration	1810:1830	tablet disintegration	1810:1830	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	5	94	theme	tablet	909:914	arg1	strength					924:931	the tablet tensile strength	905:931	the tablet tensile strength	905:931	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	94	theme	tablet	909:914	arg1	distribution					888:899	pore size distribution	878:899	pore size distribution	878:899	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	94	theme	tablet	909:914	arg1	variables					810:818	potential variables	800:818	potential variables	800:818	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	94	theme	tablet	909:914	arg1	composition					836:846	the polymorphic composition	820:846	the polymorphic composition of the lactose	820:861	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	5	94	theme	tablet	909:914	arg1	porosity					868:875	the porosity	864:875	the porosity	864:875	A linear model was built to identify which parameters impact the disintegration time, using as potential variables the polymorphic composition of the lactose, the porosity, pore size distribution and the tablet tensile strength.					
36270465	12	95	theme	binders	1780:1786	arg1	attributes					1759:1768	quality attributes	1751:1768	quality attributes of filler binders	1751:1786	The obtained insights provide guidance on the importance of quality attributes of filler binders for the prediction of tablet disintegration.					
36270465	11	96	theme	tensile	1654:1660	arg1	strength					1662:1669	tablet tensile strength	1647:1669	tablet tensile strength	1647:1669	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	3	97	from	impact	374:379	arg1	disintegration					464:477	disintegration	464:477	disintegration	464:477	For the first time, the impact of lactose polymorphism, tablet tensile strength, and pore structure parameters on disintegration were evaluated in one study.					
36270465	9	98	theme	monohydrate	1330:1340	arg1	concentration					1305:1317	A higher concentration	1296:1317	A higher concentration of lactose monohydrate in tablets	1296:1351	A higher concentration of lactose monohydrate in tablets leads to faster tablet disintegration, explained by the slower dissolution rate of lactose monohydrate compared to anhydrous and amorphous lactose.					
36270465	0	99	dep	impact	4:9	arg1	study					58:62	An integral study	46:62	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.	0:92	The impact of lactose type on disintegration: An integral study on porosity and polymorphism.					
36270465	4	100	theme	solid	581:585	arg1	fractions					587:595	different solid fractions	571:595	different solid fractions	571:595	Six different lactose qualities were compacted into tablets of different solid fractions in a formulation with 5 %w/w diclofenac sodium, 1 %w/w magnesium stearate and 2 %w/w croscarmellose sodium.					
36270465	10	101	theme	Tablet	1501:1506	arg1	driver					1556:1561	a direct driver	1547:1561	a direct driver for disintegration	1547:1580	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	10	101	theme	Tablet	1501:1506	arg1	strength					1516:1523	Tablet tensile strength	1501:1523	Tablet tensile strength	1501:1523	Tablet tensile strength was not identified as a direct driver for disintegration.					
36270465	11	102	theme	pore	1596:1599	arg1	driver					1631:1636	a mutual driver	1622:1636	a mutual driver for both tablet tensile strength and disintegration	1622:1688	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	11	102	theme	pore	1596:1599	arg1	distribution					1606:1617	the pore size distribution	1592:1617	the pore size distribution	1592:1617	Instead, the pore size distribution is a mutual driver for both tablet tensile strength and disintegration.					
36270465	13	103	theme	models	1971:1976	arg1	development					1944:1954	the development	1940:1954	the development of mechanistic models to predict tablet disintegration	1940:2009	This study can therefore be used as a starting point for quality-by-design formulation development and for the development of mechanistic models to predict tablet disintegration.					
37201890	6	0	theme	contact	979:985	arg1	angle					987:991	contact angle	979:991	contact angle	979:991	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	3	1	theme	photoswitching/back-switching	484:512	arg1	behavior					514:521	The photoswitching/back-switching behavior	480:521	The photoswitching/back-switching behavior of the samples	480:536	The photoswitching/back-switching behavior of the samples was investigated using varied LED irradiation sources.					
37201890	1	2	theme	crucial	211:217	arg1	processes					154:162	The light-induced processes	136:162	The light-induced processes performed by photofunctional polymer films	136:205	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	1	2	theme	crucial	211:217	arg1	aspects					219:225	crucial aspects	211:225	crucial aspects of developing integrated energy storage devices properly	211:282	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	8	3	theme	handleability	1491:1503	arg1	attributes					1505:1514	handleability attributes	1491:1514	handleability attributes	1491:1514	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	7	4	theme	dihedral	1274:1281	arg1	angles					1283:1288	the dihedral angles	1270:1288	the dihedral angles	1270:1288	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	2	5	from	series	379:384	arg1	compositions					466:477	different compositions	456:477	different compositions	456:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	2	6	theme	cellulose	398:406	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	8	7	dep	potential	1521:1529	arg1	uses					1531:1534	uses	1531:1534	uses	1531:1534	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	4	8	theme	acetate/azobenzene	664:681	arg1	films					683:687	cellulose acetate/azobenzene films	654:687	cellulose acetate/azobenzene films	654:687	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	5	9	theme	PEG	811:813	arg1	2.5 mJ					874:879	2.5 mJ	874:879	2.5 mJ	874:879	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	5	9	theme	PEG	811:813	arg1	enthalpies					797:806	the melting enthalpies	785:806	the melting enthalpies of PEG before and after being irradiated with blue LED light	785:867	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	6	10	theme	polarized	1035:1043	arg1	microscopy					1051:1060	polarized light microscopy	1035:1060	polarized light microscopy (PLM)	1035:1066	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	10	theme	polarized	1035:1043	arg1	PLM					1063:1065	PLM	1063:1065	PLM	1063:1065	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	7	11	theme	theoretical	1176:1186	arg1	calculations					1199:1210	theoretical electronic calculations	1176:1210	theoretical electronic calculations	1176:1210	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	2	12	theme	acetate/azobenzene	408:425	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	3	13	theme	LED	568:570	arg1	sources					584:590	varied LED irradiation sources	561:590	varied LED irradiation sources	561:590	The photoswitching/back-switching behavior of the samples was investigated using varied LED irradiation sources.					
37201890	3	14	theme	irradiation	572:582	arg1	sources					584:590	varied LED irradiation sources	561:590	varied LED irradiation sources	561:590	The photoswitching/back-switching behavior of the samples was investigated using varied LED irradiation sources.					
37201890	1	15	theme	integrated	241:250	arg1	devices					267:273	integrated energy storage devices	241:273	integrated energy storage devices	241:273	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	7	16	theme	cellulose	1367:1375	arg1	monomer					1385:1391	cellulose acetate monomer	1367:1391	cellulose acetate monomer	1367:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	4	17	theme	cellulose	654:662	arg1	films					683:687	cellulose acetate/azobenzene films	654:687	cellulose acetate/azobenzene films	654:687	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	5	18	theme	blue	854:857	arg1	light					863:867	blue LED light	854:867	blue LED light	854:867	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	7	19	theme	consistent	1223:1232	arg1	approach					1234:1241	a consistent approach	1221:1241	a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer	1221:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	2	20	theme	films	447:451	arg1	series					379:384	a series	377:384	a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	377:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	7	21	theme	cis	1337:1339	arg1	isomer					1341:1346	the trans and cis isomer	1323:1346	the trans and cis isomer in the presence of cellulose acetate monomer	1323:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	7	22	theme	non-covalent	1294:1305	arg1	interaction					1307:1317	non-covalent interaction	1294:1317	non-covalent interaction	1294:1317	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	8	23	theme	light	1575:1579	arg1	energy					1581:1586	light energy	1575:1586	light energy	1575:1586	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	2	24	theme	handleable	436:445	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	0	25	theme	Photoswitching/back-switching	0:28	arg1	assessment					30:39	Photoswitching/back-switching assessment	0:39	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light	0:117	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	7	26	theme	electronic	1188:1197	arg1	calculations					1199:1210	theoretical electronic calculations	1176:1210	theoretical electronic calculations	1176:1210	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	2	27	theme	properties	363:372	arg1	study					342:346	study	342:346	study	342:346	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	2	27	theme	properties	363:372	arg1	preparation					307:317	preparation	307:317	preparation	307:317	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	2	27	theme	properties	363:372	arg1	characterization					320:335	characterization	320:335	characterization	320:335	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	1	28	theme	energy	252:257	arg1	devices					267:273	integrated energy storage devices	241:273	integrated energy storage devices	241:273	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	0	29	theme	biobased	44:51	arg1	films					93:97	biobased cellulose acetate/azobenzene handleable films	44:97	biobased cellulose acetate/azobenzene handleable films	44:97	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	6	30	used	used	1108:1111	arg2	TGA					973:975	TGA	973:975	TGA	973:975	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	AFM					1098:1100	AFM	1098:1100	AFM	1098:1100	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	spectroscopy					941:952	FTIR and UV-visible spectroscopy	921:952	FTIR and UV-visible spectroscopy	921:952	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	calorimetry					1016:1026	differential scanning calorimetry	994:1026	differential scanning calorimetry (DSC)	994:1032	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	angle					987:991	contact angle	979:991	contact angle	979:991	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	DSC					1029:1031	DSC	1029:1031	DSC	1029:1031	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	microscopy					1051:1060	polarized light microscopy	1035:1060	polarized light microscopy (PLM)	1035:1066	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	PLM					1063:1065	PLM	1063:1065	PLM	1063:1065	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	thermogravimetry					955:970	thermogravimetry	955:970	thermogravimetry (TGA)	955:976	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	30	used	used	1108:1111	arg2	microscopy					1086:1095	atomic force microscopy	1073:1095	atomic force microscopy (AFM)	1073:1101	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	2	31	theme	optical	355:361	arg1	properties					363:372	the optical properties	351:372	the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	351:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	1	32	theme	storage	259:265	arg1	devices					267:273	integrated energy storage devices	241:273	integrated energy storage devices	241:273	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	8	33	from	potential	1521:1529	arg1	harvesting					1539:1548	harvesting	1539:1548	harvesting	1539:1548	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	7	34	from	isomer	1341:1346	arg1	presence					1355:1362	the presence	1351:1362	the presence of cellulose acetate monomer	1351:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	8	35	theme	study	1414:1418	arg1	results					1398:1404	The results	1394:1404	The results of this study	1394:1418	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	4	36	theme	back-switching	702:715	arg1	process					717:723	the back-switching process	698:723	the back-switching process's effect	698:732	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	0	37	theme	acetate/azobenzene	63:80	arg1	films					93:97	biobased cellulose acetate/azobenzene handleable films	44:97	biobased cellulose acetate/azobenzene handleable films	44:97	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	8	38	dep	materials	1470:1478	arg1	converting					1551:1560	converting	1551:1560	converting	1551:1560	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	8	38	dep	materials	1470:1478	arg1	storing					1567:1573	storing	1567:1573	storing light energy	1567:1586	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	8	38	dep	materials	1470:1478	arg1	displaying					1480:1489	displaying	1480:1489	displaying handleability attributes with potential uses in harvesting	1480:1548	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	5	39	theme	melting	789:795	arg1	2.5 mJ					874:879	2.5 mJ	874:879	2.5 mJ	874:879	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	5	39	theme	melting	789:795	arg1	enthalpies					797:806	the melting enthalpies	785:806	the melting enthalpies of PEG before and after being irradiated with blue LED light	785:867	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	6	40	theme	force	1080:1084	arg1	microscopy					1086:1095	atomic force microscopy	1073:1095	atomic force microscopy (AFM)	1073:1101	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	40	theme	force	1080:1084	arg1	AFM					1098:1100	AFM	1098:1100	AFM	1098:1100	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	8	41	theme	CA/Az1	1434:1439	arg1	films					1441:1445	CA/Az1 films	1434:1445	CA/Az1 films	1434:1445	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	8	41	theme	CA/Az1	1434:1439	arg1	materials					1470:1478	viable photoactive materials	1451:1478	viable photoactive materials	1451:1478	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	3	42	theme	samples	530:536	arg1	behavior					514:521	The photoswitching/back-switching behavior	480:521	The photoswitching/back-switching behavior of the samples	480:536	The photoswitching/back-switching behavior of the samples was investigated using varied LED irradiation sources.					
37201890	0	43	theme	cellulose	53:61	arg1	films					93:97	biobased cellulose acetate/azobenzene handleable films	44:97	biobased cellulose acetate/azobenzene handleable films	44:97	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	4	44	theme	ethylene	612:619	arg1	glycol					621:626	ethylene glycol	612:626	ethylene glycol	612:626	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	4	44	theme	ethylene	612:619	arg1	poly					607:610	poly	607:610	poly(ethylene glycol) (PEG)	607:633	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	5	45	theme	LED	859:861	arg1	light					863:867	blue LED light	854:867	blue LED light	854:867	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	2	46	theme	different	456:464	arg1	compositions					466:477	different compositions	456:477	different compositions	456:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	0	47	theme	films	93:97	arg1	assessment					30:39	Photoswitching/back-switching assessment	0:39	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light	0:117	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	6	48	theme	scanning	1007:1014	arg1	DSC					1029:1031	DSC	1029:1031	DSC	1029:1031	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	48	theme	scanning	1007:1014	arg1	calorimetry					1016:1026	differential scanning calorimetry	994:1026	differential scanning calorimetry (DSC)	994:1032	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	49	theme	FTIR	921:924	arg1	spectroscopy					941:952	FTIR and UV-visible spectroscopy	921:952	FTIR and UV-visible spectroscopy	921:952	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	50	theme	sample	1145:1150	arg1	films					1152:1156	the sample films	1141:1156	the sample films	1141:1156	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	2	51	theme	biobased	389:396	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	0	52	theme	handleable	82:91	arg1	films					93:97	biobased cellulose acetate/azobenzene handleable films	44:97	biobased cellulose acetate/azobenzene handleable films	44:97	Photoswitching/back-switching assessment of biobased cellulose acetate/azobenzene handleable films under visible-light LED irradiation.					
37201890	6	53	theme	differential	994:1005	arg1	DSC					1029:1031	DSC	1029:1031	DSC	1029:1031	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	53	theme	differential	994:1005	arg1	calorimetry					1016:1026	differential scanning calorimetry	994:1026	differential scanning calorimetry (DSC)	994:1032	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	3	54	theme	varied	561:566	arg1	sources					584:590	varied LED irradiation sources	561:590	varied LED irradiation sources	561:590	The photoswitching/back-switching behavior of the samples was investigated using varied LED irradiation sources.					
37201890	7	55	from	change	1260:1265	arg1	angles					1283:1288	the dihedral angles	1270:1288	the dihedral angles	1270:1288	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	7	55	from	change	1260:1265	arg1	interaction					1307:1317	non-covalent interaction	1294:1317	non-covalent interaction	1294:1317	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	7	56	theme	trans	1327:1331	arg1	isomer					1341:1346	the trans and cis isomer	1323:1346	the trans and cis isomer in the presence of cellulose acetate monomer	1323:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	6	57	theme	films	1152:1156	arg1	characterization					1121:1136	the characterization	1117:1136	the characterization of the sample films	1117:1156	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	8	58	theme	photoactive	1458:1468	arg1	films					1441:1445	CA/Az1 films	1434:1445	CA/Az1 films	1434:1445	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	8	58	theme	photoactive	1458:1468	arg1	materials					1470:1478	viable photoactive materials	1451:1478	viable photoactive materials	1451:1478	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	5	59	with	irradiated	838:847	arg1	light					863:867	blue LED light	854:867	blue LED light	854:867	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	1	60	theme	photofunctional	177:191	arg1	films					201:205	photofunctional polymer films	177:205	photofunctional polymer films	177:205	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	1	61	theme	light-induced	140:152	arg1	aspects					219:225	crucial aspects	211:225	crucial aspects of developing integrated energy storage devices properly	211:282	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	1	61	theme	light-induced	140:152	arg1	processes					154:162	The light-induced processes	136:162	The light-induced processes performed by photofunctional polymer films	136:205	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	6	62	theme	light	1045:1049	arg1	microscopy					1051:1060	polarized light microscopy	1035:1060	polarized light microscopy (PLM)	1035:1066	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	62	theme	light	1045:1049	arg1	PLM					1063:1065	PLM	1063:1065	PLM	1063:1065	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	8	63	theme	viable	1451:1456	arg1	films					1441:1445	CA/Az1 films	1434:1445	CA/Az1 films	1434:1445	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	8	63	theme	viable	1451:1456	arg1	materials					1470:1478	viable photoactive materials	1451:1478	viable photoactive materials	1451:1478	The results of this study revealed that CA/Az1 films are viable photoactive materials displaying handleability attributes with potential uses in harvesting, converting, and storing light energy.					
37201890	2	64	from	compositions	466:477	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	2	64	from	compositions	466:477	arg1	series					379:384	a series	377:384	a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	377:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	1	65	theme	polymer	193:199	arg1	films					201:205	photofunctional polymer films	177:205	photofunctional polymer films	177:205	The light-induced processes performed by photofunctional polymer films are crucial aspects of developing integrated energy storage devices properly.					
37201890	2	66	theme	series	379:384	arg1	properties					363:372	the optical properties	351:372	the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	351:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	6	67	theme	UV-visible	930:939	arg1	spectroscopy					941:952	FTIR and UV-visible spectroscopy	921:952	FTIR and UV-visible spectroscopy	921:952	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	68	theme	atomic	1073:1078	arg1	microscopy					1086:1095	atomic force microscopy	1073:1095	atomic force microscopy (AFM)	1073:1101	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	6	68	theme	atomic	1073:1078	arg1	AFM					1098:1100	AFM	1098:1100	AFM	1098:1100	Conveniently, FTIR and UV-visible spectroscopy, thermogravimetry (TGA), contact angle, differential scanning calorimetry (DSC), polarized light microscopy (PLM), and atomic force microscopy (AFM) were used for the characterization of the sample films.					
37201890	7	69	theme	monomer	1385:1391	arg1	presence					1355:1362	the presence	1351:1362	the presence of cellulose acetate monomer	1351:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	2	70	theme	CA/Az1	428:433	arg1	films					447:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films	389:451	biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions	389:477	Herein, we report the preparation, characterization, and study of the optical properties of a series of biobased cellulose acetate/azobenzene (CA/Az1) handleable films at different compositions.					
37201890	7	71	theme	acetate	1377:1383	arg1	monomer					1385:1391	cellulose acetate monomer	1367:1391	cellulose acetate monomer	1367:1391	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
37201890	5	72	dep	enthalpies	797:806	arg1	before					815:820	before	815:820	before	815:820	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	5	72	dep	enthalpies	797:806	arg1	irradiated					838:847	irradiated	838:847	irradiated	838:847	Interestingly, the melting enthalpies of PEG before and after being irradiated with blue LED light were 2.5 mJ and 0.8 mJ, respectively.					
37201890	4	73	theme	fabricated	752:761	arg1	films					763:767	the fabricated films	748:767	the fabricated films	748:767	Additionally, poly(ethylene glycol) (PEG) was deposited onto cellulose acetate/azobenzene films to study the back-switching process's effect and nature in the fabricated films.					
37201890	7	74	theme	energetic	1250:1258	arg1	change					1260:1265	the energetic change	1246:1265	the energetic change in the dihedral angles and non-covalent interaction	1246:1317	Complementarily, theoretical electronic calculations provided a consistent approach to the energetic change in the dihedral angles and non-covalent interaction for the trans and cis isomer in the presence of cellulose acetate monomer.					
36681216	4	0	theme	scavenging	868:877	arg1	capacities					879:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	0	theme	scavenging	868:877	arg1	higher					1015:1020	higher	1015:1020	higher	1015:1020	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	5	1	from	TP	1332:1333	arg1	beads					1347:1351	SA-based beads	1338:1351	SA-based beads	1338:1351	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	3	2	theme	compositions	757:768	arg1	values					770:775	the polyphenolic compositions values	740:775	the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system	740:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	4	3	theme	free-radical	855:866	arg1	capacities					879:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	3	theme	free-radical	855:866	arg1	higher					1015:1020	higher	1015:1020	higher	1015:1020	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	1	4	theme	34.54 	336:341	arg1	%					342:342	%	342:342	%	342:342	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	2	5	from	37 °C	450:454	arg1	storage					439:445	the 30-day storage	428:445	the 30-day storage at 37 °C	428:454	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	2	6	with	solutions	507:515	arg1	pH = 7.0					534:541	pH = 7.0	534:541	pH = 7.0	534:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	2	6	with	solutions	507:515	arg1	pH = 4.0					522:529	pH = 4.0	522:529	pH = 4.0	522:529	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	5	7	theme	solution	1305:1312	arg1	network					1291:1297	the network	1287:1297	the network of SA solution for encapsulating TP in SA-based beads	1287:1351	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	4	8	with	beads	931:935	arg1	CHs					942:944	CHs	942:944	CHs after sterilization at 98 °C or 121 °C for 30 min	942:994	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	2	9	dep	%	575:575	arg1	to					566:567	to	566:567	to	566:567	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	2	10	from	solutions	507:515	arg1	CHs					496:498	CHs	496:498	CHs at the solutions with pH = 4.0 or pH = 7.0	496:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	6	11	theme	nutritive	1453:1461	arg1	compounds					1463:1471	hydrophilic nutritive compounds	1441:1471	hydrophilic nutritive compounds based on CHs in SA-based beads	1441:1502	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	5	12	theme	SA-based	1338:1345	arg1	beads					1347:1351	SA-based beads	1338:1351	SA-based beads	1338:1351	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	3	13	theme	TP	780:781	arg1	values					770:775	the polyphenolic compositions values	740:775	the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system	740:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	4	14	theme	ferric-reducing	894:908	arg1	power					922:926	ferric-reducing antioxidant power	894:926	ferric-reducing antioxidant power	894:926	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	2	15	theme	retention	461:469	arg1	rate					471:474	the retention rate	457:474	the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0	457:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	1	16	theme	85.06 	347:352	arg1	%					342:342	%	342:342	%	342:342	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	2	17	theme	%	564:564	arg1	%					575:575	61.10 % to 80.21 %	558:575	61.10 % to 80.21 %	558:575	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	5	18	theme	scanning	1151:1158	arg1	microscope					1160:1169	confocal laser scanning microscope	1136:1169	confocal laser scanning microscope	1136:1169	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	6	19	theme	compounds	1463:1471	arg1	development					1426:1436	development	1426:1436	development	1426:1436	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	6	19	theme	compounds	1463:1471	arg1	design					1415:1420	co-encapsulation design	1398:1420	co-encapsulation design	1398:1420	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	0	20	theme	storage	110:116	arg1	stability					118:126	the storage stability	106:126	the storage stability	106:126	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	2	21	theme	%	592:592	arg1	%					603:603	67.72 % to 80.47 %	586:603	67.72 % to 80.47 %	586:603	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	3	22	theme	CHs	692:694	arg1	addition					680:687	the addition	676:687	the addition of CHs at 0.5 %	676:703	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	3	23	theme	values	770:775	arg1	retention					727:735	a greater retention	717:735	a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system	717:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	4	24	theme	DPPH	840:843	arg1	capacities					879:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	24	theme	DPPH	840:843	arg1	higher					1015:1020	higher	1015:1020	higher	1015:1020	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	0	25	from	efficiency	34:43	arg1	beads					96:100	beads	96:100	beads	96:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	4	26	theme	ABTS+	849:853	arg1	capacities					879:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	26	theme	ABTS+	849:853	arg1	higher					1015:1020	higher	1015:1020	higher	1015:1020	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	5	27	from	complexes	1204:1212	arg1	combination					1224:1234	combination	1224:1234	combination to TP	1224:1240	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	6	28	theme	hydrophilic	1441:1451	arg1	compounds					1463:1471	hydrophilic nutritive compounds	1441:1471	hydrophilic nutritive compounds based on CHs in SA-based beads	1441:1502	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	0	29	theme	Collagen	0:7	arg1	hydrolysates					9:20	Collagen hydrolysates	0:20	Collagen hydrolysates	0:20	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	4	30	theme	antioxidant	910:920	arg1	power					922:926	ferric-reducing antioxidant power	894:926	ferric-reducing antioxidant power	894:926	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	0	31	from	stability	118:126	arg1	beads					96:100	beads	96:100	beads	96:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	1	32	theme	encapsulation	288:300	arg1	rate					302:305	an encapsulation rate	285:305	an encapsulation rate of tea polyphenols (TP)	285:329	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	1	32	theme	encapsulation	288:300	arg1	TP					327:328	TP	327:328	TP	327:328	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	0	33	theme	commercial	134:143	arg1	sterilization					145:157	commercial sterilization	134:157	commercial sterilization	134:157	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	5	34	theme	CHs	1217:1219	arg1	complexes					1204:1212	tightly non-covalent complexes	1183:1212	tightly non-covalent complexes of CHs in combination to TP	1183:1240	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	4	35	theme	beads	931:935	arg1	capacities					879:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	the DPPH and ABTS+ free-radical scavenging capacities	836:888	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	35	theme	beads	931:935	arg1	higher					1015:1020	higher	1015:1020	higher	1015:1020	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	4	35	theme	beads	931:935	arg1	power					922:926	ferric-reducing antioxidant power	894:926	ferric-reducing antioxidant power	894:926	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	0	36	from	beads	96:100	arg1	efficiency					34:43	the efficiency	30:43	the efficiency of sodium alginate-encapsulated tea polyphenols in beads	30:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	0	36	from	beads	96:100	arg1	stability					118:126	the storage stability	106:126	the storage stability	106:126	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	3	37	theme	UPLC-Orbitrap-MS	797:812	arg1	system					814:819	UPLC-Orbitrap-MS system	797:819	UPLC-Orbitrap-MS system	797:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	1	38	theme	-based	204:209	arg1	beads					211:215	sodium alginates (SA)-based beads	183:215	sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs)	183:259	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	2	39	theme	30-day	432:437	arg1	storage					439:445	the 30-day storage	428:445	the 30-day storage at 37 °C	428:454	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	5	40	theme	particle	1087:1094	arg1	size					1096:1099	particle size	1087:1099	particle size	1087:1099	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	3	41	from	%	703:703	arg1	addition					680:687	the addition	676:687	the addition of CHs at 0.5 %	676:703	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	1	42	theme	mass	364:367	arg1	ratio					369:373	the mass ratio	360:373	the mass ratio of SA: CHs	360:384	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	2	43	dep	%	603:603	arg1	to					594:595	to	594:595	to	594:595	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	6	44	theme	co-encapsulation	1398:1413	arg1	design					1415:1420	co-encapsulation design	1398:1420	co-encapsulation design	1398:1420	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	1	45	theme	tea	310:312	arg1	polyphenols					314:324	tea polyphenols	310:324	tea polyphenols	310:324	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	2	46	theme	TP	479:480	arg1	rate					471:474	the retention rate	457:474	the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0	457:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	0	47	from	polyphenols	81:91	arg1	beads					96:100	beads	96:100	beads	96:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	5	48	from	combination	1224:1234	arg1	complexes					1204:1212	tightly non-covalent complexes	1183:1212	tightly non-covalent complexes of CHs in combination to TP	1183:1240	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	0	49	theme	alginate-encapsulated	55:75	arg1	polyphenols					81:91	sodium alginate-encapsulated tea polyphenols	48:91	sodium alginate-encapsulated tea polyphenols in beads	48:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	1	50	theme	polyphenols	314:324	arg1	rate					302:305	an encapsulation rate	285:305	an encapsulation rate of tea polyphenols (TP)	285:329	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	1	50	theme	polyphenols	314:324	arg1	TP					327:328	TP	327:328	TP	327:328	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	1	51	dep	%	342:342	arg1	to					344:345	to	344:345	to	344:345	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	0	52	theme	sodium	48:53	arg1	polyphenols					81:91	sodium alginate-encapsulated tea polyphenols	48:91	sodium alginate-encapsulated tea polyphenols in beads	48:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	1	53	theme	SA	378:379	arg1	CHs					382:384	SA: CHs	378:384	SA: CHs	378:384	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	5	54	from	CHs	1217:1219	arg1	combination					1224:1234	combination	1224:1234	combination to TP	1224:1240	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	4	55	from	121 °C	978:983	arg1	sterilization					952:964	sterilization	952:964	sterilization at 98 °C or 121 °C for 30 min	952:994	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	3	56	theme	greater	719:725	arg1	retention					727:735	a greater retention	717:735	a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system	717:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	5	57	theme	SA	1302:1303	arg1	solution					1305:1312	SA solution	1302:1312	SA solution for encapsulating TP in SA-based beads	1302:1351	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	6	58	dep	design	1415:1420	arg1	the					1394:1396	the	1394:1396	the	1394:1396	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	5	59	theme	UV	1116:1117	arg1	spectroscopy					1119:1130	UV spectroscopy	1116:1130	UV spectroscopy	1116:1130	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	1	60	theme	CHs	382:384	arg1	ratio					369:373	the mass ratio	360:373	the mass ratio of SA: CHs	360:384	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	6	61	theme	SA-based	1489:1496	arg1	beads					1498:1502	SA-based beads	1489:1502	SA-based beads	1489:1502	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	4	62	from	98 °C	969:973	arg1	sterilization					952:964	sterilization	952:964	sterilization at 98 °C or 121 °C for 30 min	952:994	Additionally, the DPPH and ABTS+ free-radical scavenging capacities and ferric-reducing antioxidant power of beads with CHs after sterilization at 98 °C or 121 °C for 30 min were significantly higher than which without CHs.					
36681216	5	63	theme	non-covalent	1191:1202	arg1	complexes					1204:1212	tightly non-covalent complexes	1183:1212	tightly non-covalent complexes of CHs in combination to TP	1183:1240	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	1	64	theme	collagen	233:240	arg1	hydrolysates					242:253	collagen hydrolysates	233:253	collagen hydrolysates (CHs)	233:259	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	1	64	theme	collagen	233:240	arg1	CHs					256:258	CHs	256:258	CHs	256:258	This study showed that sodium alginates (SA)-based beads reinforced with collagen hydrolysates (CHs) significantly increased an encapsulation rate of tea polyphenols (TP) from 34.54 % to 85.06 % when the mass ratio of SA: CHs increased from1.5:0 to 1.5:0.5.					
36681216	0	65	theme	polyphenols	81:91	arg1	efficiency					34:43	the efficiency	30:43	the efficiency of sodium alginate-encapsulated tea polyphenols in beads	30:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	0	65	theme	polyphenols	81:91	arg1	stability					118:126	the storage stability	106:126	the storage stability	106:126	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	2	66	from	rate	471:474	arg1	beads					485:489	beads	485:489	beads with CHs at the solutions with pH = 4.0 or pH = 7.0	485:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	5	67	theme	laser	1145:1149	arg1	microscope					1160:1169	confocal laser scanning microscope	1136:1169	confocal laser scanning microscope	1136:1169	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	6	68	from	CHs	1482:1484	arg1	beads					1498:1502	SA-based beads	1489:1502	SA-based beads	1489:1502	These findings provided suggestions for the co-encapsulation design and development of hydrophilic nutritive compounds based on CHs in SA-based beads.					
36681216	2	69	with	beads	485:489	arg1	CHs					496:498	CHs	496:498	CHs at the solutions with pH = 4.0 or pH = 7.0	496:541	And after the 30-day storage at 37 °C, the retention rate of TP in beads with CHs at the solutions with pH = 4.0 or pH = 7.0 increased from 61.10 % to 80.21 %, or from 67.72 % to 80.47 % after sterilization at 98 °C or 121 °C for 30 min, respectively.					
36681216	0	70	theme	tea	77:79	arg1	polyphenols					81:91	sodium alginate-encapsulated tea polyphenols	48:91	sodium alginate-encapsulated tea polyphenols in beads	48:100	Collagen hydrolysates improve the efficiency of sodium alginate-encapsulated tea polyphenols in beads and the storage stability after commercial sterilization.					
36681216	5	71	theme	confocal	1136:1143	arg1	microscope					1160:1169	confocal laser scanning microscope	1136:1169	confocal laser scanning microscope	1136:1169	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
36681216	3	72	theme	polyphenolic	744:755	arg1	values					770:775	the polyphenolic compositions values	740:775	the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system	740:819	Also, the addition of CHs at 0.5 % resulted in a greater retention of the polyphenolic compositions values of TP determined by UPLC-Orbitrap-MS system.					
36681216	5	73	theme	Physical	1046:1053	arg1	phenomena					1055:1063	Physical phenomena	1046:1063	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope	1046:1169	Physical phenomena based on ζ-potential, particle size, fluorescence, UV spectroscopy and confocal laser scanning microscope showed that tightly non-covalent complexes of CHs in combination to TP could be uniformly and stably distributed in the network of SA solution for encapsulating TP in SA-based beads.					
37182969	7	0	theme	tissue	1452:1457	arg1	scaffolds					1471:1479	additive manufactured tissue engineering scaffolds	1430:1479	additive manufactured tissue engineering scaffolds	1430:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	0	1	theme	dimensional	95:105	arg1	printing					107:114	three dimensional printing	89:114	three dimensional printing	89:114	A self-healing nanocomposite double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing.					
37182969	6	2	theme	nanofiber	1163:1171	arg1	cross-linkers					1173:1185	nanofiber cross-linkers	1163:1185	nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds	1163:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	6	3	theme	imine	1306:1310	arg1	bonds					1312:1316	dynamic 3D imine bonds	1295:1316	dynamic 3D imine bonds	1295:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	4	4	theme	carboxyl	896:903	arg1	chitosan					912:919	carboxyl methyl chitosan	896:919	carboxyl methyl chitosan	896:919	To do this, amino group-rich gelatin was first created by combining gelatin with carboxyl methyl chitosan.					
37182969	4	5	theme	amino	827:831	arg1	gelatin					844:850	amino group-rich gelatin	827:850	amino group-rich gelatin	827:850	To do this, amino group-rich gelatin was first created by combining gelatin with carboxyl methyl chitosan.					
37182969	1	6	theme	ongoing	295:301	arg1	challenge					303:311	an ongoing challenge	292:311	an ongoing challenge	292:311	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	7	7	theme	ncDA	1359:1362	arg1	hydrogel					1372:1379	our self-healing ncDA gelatin hydrogel	1342:1379	our self-healing ncDA gelatin hydrogel	1342:1379	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	7	8	theme	gelatin	1364:1370	arg1	hydrogel					1372:1379	our self-healing ncDA gelatin hydrogel	1342:1379	our self-healing ncDA gelatin hydrogel	1342:1379	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	5	9	theme	self-healing	936:947	arg1	hydrogel					962:969	a self-healing ncDN gelatin hydrogel	934:969	a self-healing ncDN gelatin hydrogel	934:969	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	1	10	theme	additive	193:200	arg1	scaffolds					234:242	additive manufactured tissue engineering scaffolds	193:242	additive manufactured tissue engineering scaffolds	193:242	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	2	11	theme	hydrogel	512:519	arg1	fabrication					468:478	fabrication	468:478	fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing	468:570	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	2	11	theme	hydrogel	512:519	arg1	challenge					583:591	a challenge	581:591	a challenge	581:591	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	6	12	theme	double	1246:1251	arg1	networks					1253:1260	the double networks	1242:1260	the double networks of Gel/CMCh	1242:1272	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	4	13	theme	group-rich	833:842	arg1	gelatin					844:850	amino group-rich gelatin	827:850	amino group-rich gelatin	827:850	To do this, amino group-rich gelatin was first created by combining gelatin with carboxyl methyl chitosan.					
37182969	1	14	theme	manufactured	202:213	arg1	scaffolds					234:242	additive manufactured tissue engineering scaffolds	193:242	additive manufactured tissue engineering scaffolds	193:242	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	7	15	theme	self-healing	1346:1357	arg1	hydrogel					1372:1379	our self-healing ncDA gelatin hydrogel	1342:1379	our self-healing ncDA gelatin hydrogel	1342:1379	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	1	16	theme	tissue	215:220	arg1	scaffolds					234:242	additive manufactured tissue engineering scaffolds	193:242	additive manufactured tissue engineering scaffolds	193:242	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	1	17	theme	Extrusion-based	117:131	arg1	printing					156:163	Extrusion-based three-dimensional (3D) printing	117:163	Extrusion-based three-dimensional (3D) printing of gelatin	117:174	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	1	18	theme	engineering	222:232	arg1	scaffolds					234:242	additive manufactured tissue engineering scaffolds	193:242	additive manufactured tissue engineering scaffolds	193:242	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	0	19	theme	double	29:34	arg1	hydrogel					76:83	double network bacterial nanocellulose/gelatin hydrogel	29:83	double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing	29:114	A self-healing nanocomposite double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing.					
37182969	7	20	theme	manufactured	1439:1450	arg1	scaffolds					1471:1479	additive manufactured tissue engineering scaffolds	1430:1479	additive manufactured tissue engineering scaffolds	1430:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	5	21	theme	bacterial	1117:1125	arg1	dBNC					1142:1145	dBNC	1142:1145	dBNC	1142:1145	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	21	theme	bacterial	1117:1125	arg1	nanocellulose					1127:1139	dialdehyde-functionalized bacterial nanocellulose	1091:1139	dialdehyde-functionalized bacterial nanocellulose (dBNC)	1091:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	1	22	theme	three-dimensional	133:149	arg1	printing					156:163	Extrusion-based three-dimensional (3D) printing	117:163	Extrusion-based three-dimensional (3D) printing of gelatin	117:174	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	2	23	theme	37 °C.	454:459	arg1	temperature					439:449	physiological temperature	425:449	physiological temperature of 37 °C.	425:459	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	3	24	theme	self-healing	613:624	arg1	hydrogel					670:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	5	25	theme	imine	1010:1014	arg1	bonds					1016:1020	imine bonds	1010:1020	imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC)	1010:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	3	26	theme	high	699:702	arg1	thermo-processability					704:724	high thermo-processability	699:724	high thermo-processability	699:724	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	7	27	theme	promising	1412:1420	arg1	ink					1422:1424	a promising ink	1410:1424	a promising ink for additive manufactured tissue engineering scaffolds	1410:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	7	27	theme	promising	1412:1420	arg1	potential					1397:1405	great potential	1391:1405	great potential	1391:1405	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	5	28	theme	dialdehyde-functionalized	1091:1115	arg1	dBNC					1142:1145	dBNC	1142:1145	dBNC	1142:1145	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	28	theme	dialdehyde-functionalized	1091:1115	arg1	nanocellulose					1127:1139	dialdehyde-functionalized bacterial nanocellulose	1091:1139	dialdehyde-functionalized bacterial nanocellulose (dBNC)	1091:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	1	29	theme	gelatin	168:174	arg1	printing					156:163	Extrusion-based three-dimensional (3D) printing	117:163	Extrusion-based three-dimensional (3D) printing of gelatin	117:174	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	0	30	theme	bacterial	44:52	arg1	hydrogel					76:83	double network bacterial nanocellulose/gelatin hydrogel	29:83	double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing	29:114	A self-healing nanocomposite double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing.					
37182969	5	31	theme	ncDN	949:952	arg1	hydrogel					962:969	a self-healing ncDN gelatin hydrogel	934:969	a self-healing ncDN gelatin hydrogel	934:969	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	7	32	theme	great	1391:1395	arg1	ink					1422:1424	a promising ink	1410:1424	a promising ink for additive manufactured tissue engineering scaffolds	1410:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	7	32	theme	great	1391:1395	arg1	potential					1397:1405	great potential	1391:1405	great potential	1391:1405	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	0	33	theme	network	36:42	arg1	hydrogel					76:83	double network bacterial nanocellulose/gelatin hydrogel	29:83	double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing	29:114	A self-healing nanocomposite double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing.					
37182969	2	34	theme	gelatin	504:510	arg1	hydrogel					512:519	a thermo-processable gelatin hydrogel	483:519	a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing	483:570	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	3	35	theme	ncDN	656:659	arg1	hydrogel					670:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	2	36	theme	physiological	425:437	arg1	temperature					439:449	physiological temperature	425:449	physiological temperature of 37 °C.	425:459	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	2	37	theme	thermo-processable	485:502	arg1	hydrogel					512:519	a thermo-processable gelatin hydrogel	483:519	a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing	483:570	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	5	38	theme	gelatin	954:960	arg1	hydrogel					962:969	a self-healing ncDN gelatin hydrogel	934:969	a self-healing ncDN gelatin hydrogel	934:969	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	3	39	theme	nanocomposite	626:638	arg1	hydrogel					670:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	0	40	theme	nanocellulose/gelatin	54:74	arg1	hydrogel					76:83	double network bacterial nanocellulose/gelatin hydrogel	29:83	double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing	29:114	A self-healing nanocomposite double network bacterial nanocellulose/gelatin hydrogel for three dimensional printing.					
37182969	4	41	theme	methyl	905:910	arg1	chitosan					912:919	carboxyl methyl chitosan	896:919	carboxyl methyl chitosan	896:919	To do this, amino group-rich gelatin was first created by combining gelatin with carboxyl methyl chitosan.					
37182969	5	42	theme	nanocellulose	1127:1139	arg1	blend					1034:1038	the blend	1030:1038	the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC)	1030:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	3	43	theme	double-network	640:653	arg1	hydrogel					670:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	6	44	theme	dynamic	1295:1301	arg1	bonds					1312:1316	dynamic 3D imine bonds	1295:1316	dynamic 3D imine bonds	1295:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	3	45	theme	mechanical	743:752	arg1	strength					754:761	mechanical strength	743:761	mechanical strength	743:761	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	5	46	theme	methyl	1060:1065	arg1	Gel/CMCh					1077:1084	Gel/CMCh	1077:1084	Gel/CMCh	1077:1084	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	46	theme	methyl	1060:1065	arg1	chitosan					1067:1074	gelatin/carboxyl methyl chitosan	1043:1074	gelatin/carboxyl methyl chitosan (Gel/CMCh)	1043:1085	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	47	theme	in-situ	989:995	arg1	formation					997:1005	an in-situ formation	986:1005	an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC)	986:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	48	theme	bonds	1016:1020	arg1	formation					997:1005	an in-situ formation	986:1005	an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC)	986:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	49	theme	gelatin/carboxyl	1043:1058	arg1	Gel/CMCh					1077:1084	Gel/CMCh	1077:1084	Gel/CMCh	1077:1084	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	5	49	theme	gelatin/carboxyl	1043:1058	arg1	chitosan					1067:1074	gelatin/carboxyl methyl chitosan	1043:1074	gelatin/carboxyl methyl chitosan (Gel/CMCh)	1043:1085	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	6	50	theme	bonds	1312:1316	arg1	formation					1282:1290	formation	1282:1290	formation of dynamic 3D imine bonds	1282:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	5	51	theme	chitosan	1067:1074	arg1	blend					1034:1038	the blend	1030:1038	the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC)	1030:1146	Afterwards, a self-healing ncDN gelatin hydrogel was formed via an in-situ formation of imine bonds between the blend of gelatin/carboxyl methyl chitosan (Gel/CMCh) and dialdehyde-functionalized bacterial nanocellulose (dBNC).					
37182969	2	52	theme	mild	356:359	arg1	temperatures					361:372	mild temperatures	356:372	mild temperatures	356:372	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	1	53	theme	thermal	259:265	arg1	instability					267:277	gelatin's thermal instability	249:277	gelatin's thermal instability	249:277	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	2	54	theme	additive	549:556	arg1	manufacturing					558:570	extrusion-based additive manufacturing	533:570	extrusion-based additive manufacturing	533:570	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	6	55	theme	capable	1187:1193	arg1	cross-linkers					1173:1185	nanofiber cross-linkers	1163:1185	nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds	1163:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	6	56	theme	3D	1303:1304	arg1	bonds					1312:1316	dynamic 3D imine bonds	1295:1316	dynamic 3D imine bonds	1295:1316	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	6	57	theme	Gel/CMCh	1265:1272	arg1	networks					1253:1260	the double networks	1242:1260	the double networks of Gel/CMCh	1242:1272	dBNC plays as nanofiber cross-linkers capable of simultaneously crosslinking and reinforcing the double networks of Gel/CMCh through formation of dynamic 3D imine bonds.					
37182969	1	58	dep	three-dimensional	133:149	arg1	3D					152:153	3D	152:153	3D	152:153	Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge.					
37182969	7	59	theme	additive	1430:1437	arg1	scaffolds					1471:1479	additive manufactured tissue engineering scaffolds	1430:1479	additive manufactured tissue engineering scaffolds	1430:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	2	60	theme	extrusion-based	533:547	arg1	manufacturing					558:570	extrusion-based additive manufacturing	533:570	extrusion-based additive manufacturing	533:570	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	7	61	theme	engineering	1459:1469	arg1	scaffolds					1471:1479	additive manufactured tissue engineering scaffolds	1430:1479	additive manufactured tissue engineering scaffolds	1430:1479	Based on our findings, our self-healing ncDA gelatin hydrogel displayed great potential as a promising ink for additive manufactured tissue engineering scaffolds.					
37182969	3	62	theme	gelatin	662:668	arg1	hydrogel					670:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	a self-healing nanocomposite double-network (ncDN) gelatin hydrogel	611:677	To achieve this, a self-healing nanocomposite double-network (ncDN) gelatin hydrogel was fabricated with high thermo-processability, shear-thinning, mechanical strength, self-healing, self-recovery, and biocompatibility.					
37182969	2	63	theme	significant	386:396	arg1	which					375:379	which	375:379	which	375:379	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
37182969	2	63	theme	significant	386:396	arg1	limitation					398:407	a significant limitation	384:407	a significant limitation for using it at physiological temperature of 37 °C.	384:459	The gelatin tends to suddenly collapse at mild temperatures, which is a significant limitation for using it at physiological temperature of 37 °C. Hence, fabrication of a thermo-processable gelatin hydrogel adapted for extrusion-based additive manufacturing is still a challenge.					
35764109	0	0	theme	aqueous	89:95	arg1	solution					97:104	aqueous solution	89:104	aqueous solution	89:104	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	7	1	theme	capacity	1201:1208	arg1	rate					1220:1223	the adsorption capacity retention rate	1186:1223	the adsorption capacity retention rate of CP	1186:1229	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	1	theme	capacity	1201:1208	arg1	%					1246:1246	71.32%	1241:1246	71.32%	1241:1246	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	8	2	from	microspheres	1334:1345	arg1	pollution					1417:1425	dyeing wastewater pollution	1399:1425	dyeing wastewater pollution	1399:1425	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	8	2	from	microspheres	1334:1345	arg1	printing					1386:1393	printing	1386:1393	printing	1386:1393	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	6	3	theme	adsorption	1104:1113	arg1	process					1115:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	6	4	theme	calculation	1021:1031	arg1	results					1033:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	1	5	theme	high	237:240	arg1	toxicity					242:249	its high toxicity	233:249	its high toxicity	233:249	Hexavalent chromium is widely used in industrial fields, but its pollution has posed a great threat to the environment due to its high toxicity.					
35764109	8	6	theme	Cr	1376:1377	arg1	removal					1365:1371	the effective removal	1351:1371	the effective removal of Cr(VI)	1351:1381	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	2	7	theme	chitosan-based	265:278	arg1	biosorbent					292:301	a chitosan-based microsphere biosorbent	263:301	a chitosan-based microsphere biosorbent (CP)	263:306	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	2	7	theme	chitosan-based	265:278	arg1	CP					304:305	CP	304:305	CP	304:305	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	4	8	theme	R	707:707	arg1	rate					646:649	the removal rate	634:649	the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR)	634:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	6	9	theme	chemical	1095:1102	arg1	process					1115:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	7	10	theme	retention	1210:1218	arg1	rate					1220:1223	the adsorption capacity retention rate	1186:1223	the adsorption capacity retention rate of CP	1186:1229	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	10	theme	retention	1210:1218	arg1	%					1246:1246	71.32%	1241:1246	71.32%	1241:1246	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	4	11	theme	50 mg L-1	675:683	arg1	EBBR					710:713	EBBR	710:713	EBBR	710:713	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	11	theme	50 mg L-1	675:683	arg1	R					707:707	50 mg L-1 Eriochrome blue-black R	675:707	50 mg L-1 Eriochrome blue-black R (EBBR)	675:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	7	12	theme	microspheres	1142:1153	arg1	CP					1155:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	6	13	theme	monolayer	1080:1088	arg1	process					1115:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	4	14	theme	CP	616:617	arg1	0.25 g L-1					622:631	0.25 g L-1	622:631	0.25 g L-1	622:631	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	14	theme	CP	616:617	arg1	CP					616:617	CP	616:617	CP	616:617	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	14	theme	CP	616:617	arg1	amount					606:611	the amount	602:611	the amount of CP	602:617	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	15	dep	Cr	664:665	arg1	VI					667:668	VI	667:668	VI	667:668	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	5	16	theme	adsorption	787:796	arg1	180 min					811:817	180 min	811:817	180 min	811:817	The time required for CP to reach adsorption equilibrium (180 min) was significantly shorter than that of chitosan microspheres (540 min), and the adsorption rate was significantly improved.					
35764109	5	16	theme	adsorption	787:796	arg1	equilibrium					798:808	adsorption equilibrium	787:808	adsorption equilibrium (180 min)	787:818	The time required for CP to reach adsorption equilibrium (180 min) was significantly shorter than that of chitosan microspheres (540 min), and the adsorption rate was significantly improved.					
35764109	4	17	theme	removal	638:644	arg1	rate					646:649	the removal rate	634:649	the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR)	634:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	7	18	theme	adsorption	1259:1268	arg1	cycles					1270:1275	four adsorption cycles	1254:1275	four adsorption cycles	1254:1275	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	19	theme	composite	1132:1140	arg1	CP					1155:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	0	20	theme	composite	15:23	arg1	microspheres					25:36	Chitosan-based composite microspheres	0:36	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.	0:105	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	0	21	from	treatment	42:50	arg1	solution					97:104	aqueous solution	89:104	aqueous solution	89:104	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	6	22	theme	thermodynamic	1007:1019	arg1	calculation					1021:1031	thermodynamic calculation	1007:1031	thermodynamic calculation	1007:1031	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	3	23	theme	chitosan	558:565	arg1	168.91 mg g-1					581:593	168.91 mg g-1	581:593	168.91 mg g-1	581:593	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	3	23	theme	chitosan	558:565	arg1	microspheres					567:578	chitosan microspheres	558:578	chitosan microspheres (168.91 mg g-1)	558:594	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	6	24	theme	model	997:1001	arg1	results					1033:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	2	25	theme	polymerization	379:392	arg1	method					394:399	inverse emulsion polymerization method	362:399	inverse emulsion polymerization method	362:399	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	0	26	theme	Chitosan-based	0:13	arg1	microspheres					25:36	Chitosan-based composite microspheres	0:36	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.	0:105	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	1	27	used	used	137:140	arg2	chromium					118:125	Hexavalent chromium	107:125	Hexavalent chromium	107:125	Hexavalent chromium is widely used in industrial fields, but its pollution has posed a great threat to the environment due to its high toxicity.					
35764109	8	28	theme	prepared	1307:1314	arg1	microspheres					1334:1345	an easily prepared and biomass-based microspheres	1297:1345	an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption	1297:1444	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	2	29	theme	emulsion	370:377	arg1	method					394:399	inverse emulsion polymerization method	362:399	inverse emulsion polymerization method	362:399	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	1	30	theme	Hexavalent	107:116	arg1	chromium					118:125	Hexavalent chromium	107:125	Hexavalent chromium	107:125	Hexavalent chromium is widely used in industrial fields, but its pollution has posed a great threat to the environment due to its high toxicity.					
35764109	3	31	theme	adsorption	453:462	arg1	capacity					464:471	the maximum adsorption capacity	441:471	the maximum adsorption capacity of composite microspheres	441:497	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	4	32	theme	blue-black	696:705	arg1	EBBR					710:713	EBBR	710:713	EBBR	710:713	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	32	theme	blue-black	696:705	arg1	R					707:707	50 mg L-1 Eriochrome blue-black R	675:707	50 mg L-1 Eriochrome blue-black R (EBBR)	675:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	7	33	theme	Biomass	1124:1130	arg1	CP					1155:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	5	34	theme	chitosan	859:866	arg1	microspheres					868:879	chitosan microspheres	859:879	chitosan microspheres (540 min)	859:889	The time required for CP to reach adsorption equilibrium (180 min) was significantly shorter than that of chitosan microspheres (540 min), and the adsorption rate was significantly improved.					
35764109	5	34	theme	chitosan	859:866	arg1	540 min					882:888	540 min	882:888	540 min	882:888	The time required for CP to reach adsorption equilibrium (180 min) was significantly shorter than that of chitosan microspheres (540 min), and the adsorption rate was significantly improved.					
35764109	2	35	theme	microsphere	280:290	arg1	biosorbent					292:301	a chitosan-based microsphere biosorbent	263:301	a chitosan-based microsphere biosorbent (CP)	263:306	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	2	35	theme	microsphere	280:290	arg1	CP					304:305	CP	304:305	CP	304:305	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	8	36	theme	biomass-based	1320:1332	arg1	microspheres					1334:1345	an easily prepared and biomass-based microspheres	1297:1345	an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption	1297:1444	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	1	37	theme	great	194:198	arg1	threat					200:205	a great threat	192:205	a great threat to the environment due to its high toxicity	192:249	Hexavalent chromium is widely used in industrial fields, but its pollution has posed a great threat to the environment due to its high toxicity.					
35764109	3	38	theme	optimal	412:418	arg1	pH = 3					432:437	pH = 3	432:437	pH = 3	432:437	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	3	38	theme	optimal	412:418	arg1	conditions					420:429	the optimal conditions	408:429	the optimal conditions (pH = 3)	408:438	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	8	39	theme	effective	1355:1363	arg1	removal					1365:1371	the effective removal	1351:1371	the effective removal of Cr(VI)	1351:1381	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	6	40	theme	kinetic	989:995	arg1	model					997:1001	pseudo-second-order kinetic model	969:1001	pseudo-second-order kinetic model	969:1001	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	6	41	theme	model	962:966	arg1	results					1033:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results	944:1039	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	4	42	theme	Cr	664:665	arg1	rate					646:649	the removal rate	634:649	the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR)	634:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	8	43	theme	dyeing	1399:1404	arg1	pollution					1417:1425	dyeing wastewater pollution	1399:1425	dyeing wastewater pollution	1399:1425	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	3	44	theme	maximum	445:451	arg1	capacity					464:471	the maximum adsorption capacity	441:471	the maximum adsorption capacity of composite microspheres	441:497	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	0	45	theme	chromium	66:73	arg1	treatment					42:50	treatment	42:50	treatment of hexavalent chromium and EBBR from aqueous solution	42:104	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	6	46	theme	isotherm	953:960	arg1	model					962:966	Langmuir isotherm model	944:966	Langmuir isotherm model	944:966	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	3	47	theme	microspheres	486:497	arg1	capacity					464:471	the maximum adsorption capacity	441:471	the maximum adsorption capacity of composite microspheres	441:497	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	0	48	theme	hexavalent	55:64	arg1	chromium					66:73	chromium	66:73	chromium	66:73	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	8	49	theme	wastewater	1406:1415	arg1	pollution					1417:1425	dyeing wastewater pollution	1399:1425	dyeing wastewater pollution	1399:1425	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	1	50	theme	industrial	145:154	arg1	fields					156:161	industrial fields	145:161	industrial fields	145:161	Hexavalent chromium is widely used in industrial fields, but its pollution has posed a great threat to the environment due to its high toxicity.					
35764109	7	51	contain	has	1158:1160	arg1	CP					1155:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP	1124:1156	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	51	contain	has	1158:1160	arg2	selectivity					1170:1180	obvious selectivity	1162:1180	obvious selectivity	1162:1180	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	4	52	theme	Eriochrome	685:694	arg1	EBBR					710:713	EBBR	710:713	EBBR	710:713	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	4	52	theme	Eriochrome	685:694	arg1	R					707:707	50 mg L-1 Eriochrome blue-black R	675:707	50 mg L-1 Eriochrome blue-black R (EBBR)	675:714	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	6	53	theme	endothermic	1055:1065	arg1	process					1115:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	6	54	theme	Langmuir	944:951	arg1	model					962:966	Langmuir isotherm model	944:966	Langmuir isotherm model	944:966	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	8	55	dep	Cr	1376:1377	arg1	VI					1379:1380	VI	1379:1380	VI	1379:1380	This work proposed an easily prepared and biomass-based microspheres for the effective removal of Cr(VI) in printing and dyeing wastewater pollution through adsorption.					
35764109	5	56	theme	adsorption	900:909	arg1	rate					911:914	the adsorption rate	896:914	the adsorption rate	896:914	The time required for CP to reach adsorption equilibrium (180 min) was significantly shorter than that of chitosan microspheres (540 min), and the adsorption rate was significantly improved.					
35764109	3	57	theme	composite	476:484	arg1	microspheres					486:497	composite microspheres	476:497	composite microspheres	476:497	Under the optimal conditions (pH = 3), the maximum adsorption capacity of composite microspheres can reach 299.89 mg g-1, which is much higher than that of chitosan microspheres (168.91 mg g-1).					
35764109	6	58	theme	spontaneous	1067:1077	arg1	process					1115:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	an endothermic spontaneous, monolayer, and chemical adsorption process	1052:1121	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	0	59	theme	EBBR	79:82	arg1	treatment					42:50	treatment	42:50	treatment of hexavalent chromium and EBBR from aqueous solution	42:104	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	0	60	from	solution	97:104	arg1	EBBR					79:82	EBBR	79:82	EBBR	79:82	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	0	60	from	solution	97:104	arg1	treatment					42:50	treatment	42:50	treatment of hexavalent chromium and EBBR from aqueous solution	42:104	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	0	60	from	solution	97:104	arg1	chromium					66:73	chromium	66:73	chromium	66:73	Chitosan-based composite microspheres for treatment of hexavalent chromium and EBBR from aqueous solution.					
35764109	6	61	theme	pseudo-second-order	969:987	arg1	model					997:1001	pseudo-second-order kinetic model	969:1001	pseudo-second-order kinetic model	969:1001	Langmuir isotherm model, pseudo-second-order kinetic model and thermodynamic calculation results penetrated an endothermic spontaneous, monolayer, and chemical adsorption process.					
35764109	2	62	theme	inverse	362:368	arg1	method					394:399	inverse emulsion polymerization method	362:399	inverse emulsion polymerization method	362:399	We created a chitosan-based microsphere biosorbent (CP) by combining polyethyleneimine with chitosan adopting inverse emulsion polymerization method.					
35764109	7	63	theme	adsorption	1190:1199	arg1	rate					1220:1223	the adsorption capacity retention rate	1186:1223	the adsorption capacity retention rate of CP	1186:1229	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	63	theme	adsorption	1190:1199	arg1	%					1246:1246	71.32%	1241:1246	71.32%	1241:1246	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	64	theme	CP	1228:1229	arg1	rate					1220:1223	the adsorption capacity retention rate	1186:1223	the adsorption capacity retention rate of CP	1186:1229	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	7	64	theme	CP	1228:1229	arg1	%					1246:1246	71.32%	1241:1246	71.32%	1241:1246	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35764109	4	65	theme	50 mg L-1	654:662	arg1	Cr					664:665	50 mg L-1 Cr	654:665	50 mg L-1 Cr(VI)	654:669	When the amount of CP is 0.25 g L-1, the removal rate of 50 mg L-1 Cr(VI) and 50 mg L-1 Eriochrome blue-black R (EBBR) can reach 95% and 99%, respectively.					
35764109	7	66	theme	obvious	1162:1168	arg1	selectivity					1170:1180	obvious selectivity	1162:1180	obvious selectivity	1162:1180	Biomass composite microspheres CP has obvious selectivity and the adsorption capacity retention rate of CP was still 71.32% after four adsorption cycles.					
35298857	6	0	theme	modulus	960:966	arg1	contrast					968:975	The modulus contrast	956:975	The modulus contrast between the stiff and soft phases	956:1009	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	3	1	from	contrast	487:494	arg1	hydrogels					499:507	hydrogels	499:507	hydrogels	499:507	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	8	2	with	hydrogels	1415:1423	arg1	groups					1441:1446	functional groups	1430:1446	functional groups that can coordinate with metal ions	1430:1482	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	1	3	theme	high	171:174	arg1	toughness					176:184	high toughness	171:184	high toughness	171:184	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	4	4	theme	Fe3+	550:553	arg1	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	4	theme	Fe3+	550:553	arg1	/CA-complex					555:565	Fe3+ /CA-complex	550:565	Fe3+ /CA-complex	550:565	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	5	theme	ions	815:818	arg1	photoreduction					790:803	photoreduction	790:803	photoreduction of ferric ions (Fe3+ )	790:826	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	8	6	from	potential	1283:1291	arg1	synthesis					1300:1308	the synthesis	1296:1308	the synthesis of smart hydrogels with light-programmable mechanical performances	1296:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	4	7	theme	Ferric	522:527	arg1	cross-linker					604:615	a light-responsive ionic cross-linker	579:615	a light-responsive ionic cross-linker	579:615	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	7	theme	Ferric	522:527	arg1	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	7	theme	Ferric	522:527	arg1	/CA-complex					555:565	Fe3+ /CA-complex	550:565	Fe3+ /CA-complex	550:565	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	8	theme	ferric	808:813	arg1	ions					815:818	ferric ions	808:818	ferric ions (Fe3+ )	808:826	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	8	theme	ferric	808:813	arg1	Fe3+					821:824	Fe3+	821:824	Fe3+	821:824	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	2	9	theme	toughening	308:317	arg1	strategy					319:326	a toughening strategy	306:326	a toughening strategy for hydrogels based on the controlling of modulus heterogeneity	306:390	This inspires a toughening strategy for hydrogels based on the controlling of modulus heterogeneity.					
35298857	6	10	theme	several	1041:1047	arg1	factors					1059:1065	several influence factors	1041:1065	several influence factors	1041:1065	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	8	11	theme	smart	1313:1317	arg1	hydrogels					1319:1327	smart hydrogels	1313:1327	smart hydrogels with light-programmable mechanical performances	1313:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	4	12	used	used	571:574	arg2	/CA-complex					555:565	Fe3+ /CA-complex	550:565	Fe3+ /CA-complex	550:565	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	12	used	used	571:574	arg2	cross-linker					604:615	a light-responsive ionic cross-linker	579:615	a light-responsive ionic cross-linker	579:615	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	12	used	used	571:574	arg2	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	6	13	theme	modulus	1083:1089	arg1	contrast					1091:1098	the maximum modulus contrast	1071:1098	the maximum modulus contrast	1071:1098	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	4	14	dep	form	721:724	arg1	realize					748:754	realize	748:754	realize light-triggered softening through photoreduction of ferric ions (Fe3+ )	748:826	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	3	15	theme	large	481:485	arg1	contrast					487:494	large contrast	481:494	large contrast in hydrogels	481:507	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	0	16	theme	Mechanical	105:114	arg1	Toughening					116:125	Mechanical Toughening	105:125	Mechanical Toughening	105:125	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	4	17	theme	acid	536:539	arg1	cross-linker					604:615	a light-responsive ionic cross-linker	579:615	a light-responsive ionic cross-linker	579:615	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	17	theme	acid	536:539	arg1	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	17	theme	acid	536:539	arg1	/CA-complex					555:565	Fe3+ /CA-complex	550:565	Fe3+ /CA-complex	550:565	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	7	18	theme	stripe-patterned	1160:1175	arg1	hydrogel					1177:1184	the stripe-patterned hydrogel	1156:1184	the stripe-patterned hydrogel	1156:1184	As a result, the toughness of the stripe-patterned hydrogel is enhanced by 3.5 times comparing to that hydrogel without a pattern.					
35298857	6	19	theme	factors	1059:1065	arg1	control					1030:1036	control	1030:1036	control of several influence factors	1030:1065	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	5	20	theme	soft	899:902	arg1	segments					904:911	alternating stiff and soft segments	877:911	alternating stiff and soft segments	877:911	Based on this, a stripe-patterned hydrogel with alternating stiff and soft segments can be fabricated through photopatterning.					
35298857	0	21	theme	Facile	2:7	arg1	Approach					9:16	A Facile Approach	0:16	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application	0:92	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	4	22	theme	citric	529:534	arg1	acid					536:539	citric acid	529:539	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	1	23	from	tissues	146:152	arg1	nature					157:162	nature	157:162	nature	157:162	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	8	24	theme	great	1277:1281	arg1	potential					1283:1291	great potential	1277:1291	great potential in the synthesis of smart hydrogels with light-programmable mechanical performances	1277:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	5	25	with	hydrogel	863:870	arg1	segments					904:911	alternating stiff and soft segments	877:911	alternating stiff and soft segments	877:911	Based on this, a stripe-patterned hydrogel with alternating stiff and soft segments can be fabricated through photopatterning.					
35298857	4	26	theme	light-responsive	581:596	arg1	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	26	theme	light-responsive	581:596	arg1	cross-linker					604:615	a light-responsive ionic cross-linker	579:615	a light-responsive ionic cross-linker	579:615	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	8	27	with	hydrogels	1319:1327	arg1	performances					1364:1375	light-programmable mechanical performances	1334:1375	light-programmable mechanical performances	1334:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	1	28	theme	anisotropic	201:211	arg1	structures					213:222	anisotropic structures	201:222	anisotropic structures with spatially regulated composition and modulus	201:271	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	8	29	theme	functional	1430:1439	arg1	groups					1441:1446	functional groups	1430:1446	functional groups that can coordinate with metal ions	1430:1482	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	3	30	theme	facile	403:408	arg1	approach					410:417	a facile approach	401:417	a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels	401:507	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	7	31	theme	hydrogel	1177:1184	arg1	result					1131:1136	a result	1129:1136	a result	1129:1136	As a result, the toughness of the stripe-patterned hydrogel is enhanced by 3.5 times comparing to that hydrogel without a pattern.					
35298857	7	31	theme	hydrogel	1177:1184	arg1	toughness					1143:1151	the toughness	1139:1151	the toughness of the stripe-patterned hydrogel	1139:1184	As a result, the toughness of the stripe-patterned hydrogel is enhanced by 3.5 times comparing to that hydrogel without a pattern.					
35298857	4	32	theme	Alg/PAAm	670:677	arg1	hydrogel					680:687	an alginate/polyacrylamide (Alg/PAAm) hydrogel	642:687	an alginate/polyacrylamide (Alg/PAAm) hydrogel	642:687	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	3	33	theme	spatial	446:452	arg1	heterogeneity					462:474	light-regulated spatial modulus heterogeneity	430:474	light-regulated spatial modulus heterogeneity	430:474	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	4	34	theme	ionic	598:602	arg1	complex					541:547	Ferric citric acid complex	522:547	Ferric citric acid complex (Fe3+ /CA-complex)	522:566	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	4	34	theme	ionic	598:602	arg1	cross-linker					604:615	a light-responsive ionic cross-linker	579:615	a light-responsive ionic cross-linker	579:615	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	1	35	with	structures	213:222	arg1	modulus					265:271	modulus	265:271	modulus	265:271	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	1	35	with	structures	213:222	arg1	composition					249:259	spatially regulated composition	229:259	spatially regulated composition	229:259	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	6	36	theme	maximum	1075:1081	arg1	contrast					1091:1098	the maximum modulus contrast	1071:1098	the maximum modulus contrast	1071:1098	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	6	37	theme	soft	999:1002	arg1	phases					1004:1009	the stiff and soft phases	985:1009	the stiff and soft phases	985:1009	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	5	38	theme	alternating	877:887	arg1	segments					904:911	alternating stiff and soft segments	877:911	alternating stiff and soft segments	877:911	Based on this, a stripe-patterned hydrogel with alternating stiff and soft segments can be fabricated through photopatterning.					
35298857	0	39	theme	Anisotropic	22:32	arg1	Hydrogel					34:41	Anisotropic Hydrogel	22:41	Anisotropic Hydrogel	22:41	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	3	40	theme	modulus	454:460	arg1	heterogeneity					462:474	light-regulated spatial modulus heterogeneity	430:474	light-regulated spatial modulus heterogeneity	430:474	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	1	41	theme	regulated	239:247	arg1	composition					249:259	spatially regulated composition	229:259	spatially regulated composition	229:259	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	0	42	theme	Light-Regulated	48:62	arg1	Stiffness					64:72	Light-Regulated Stiffness	48:72	Light-Regulated Stiffness	48:72	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	6	43	theme	stiff	989:993	arg1	phases					1004:1009	the stiff and soft phases	985:1009	the stiff and soft phases	985:1009	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	0	44	with	Approach	9:16	arg1	Stiffness					64:72	Light-Regulated Stiffness	48:72	Light-Regulated Stiffness	48:72	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	0	44	with	Approach	9:16	arg1	Application					82:92	Its Application	78:92	Its Application	78:92	A Facile Approach for Anisotropic Hydrogel with Light-Regulated Stiffness and Its Application to Achieve Mechanical Toughening.					
35298857	2	45	theme	modulus	370:376	arg1	heterogeneity					378:390	modulus heterogeneity	370:390	modulus heterogeneity	370:390	This inspires a toughening strategy for hydrogels based on the controlling of modulus heterogeneity.					
35298857	3	46	theme	light-regulated	430:444	arg1	heterogeneity					462:474	light-regulated spatial modulus heterogeneity	430:474	light-regulated spatial modulus heterogeneity	430:474	Herein, a facile approach to realize light-regulated spatial modulus heterogeneity with large contrast in hydrogels is proposed.					
35298857	1	47	theme	Many	128:131	arg1	tissues					146:152	Many load-bearing tissues	128:152	Many load-bearing tissues in nature	128:162	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	1	48	theme	load-bearing	133:144	arg1	tissues					146:152	Many load-bearing tissues	128:152	Many load-bearing tissues in nature	128:162	Many load-bearing tissues in nature obtain high toughness by fabricating anisotropic structures with spatially regulated composition and modulus at the macroscale.					
35298857	8	49	theme	hydrogels	1319:1327	arg1	synthesis					1300:1308	the synthesis	1296:1308	the synthesis of smart hydrogels with light-programmable mechanical performances	1296:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	4	50	theme	light-triggered	756:770	arg1	softening					772:780	light-triggered softening	756:780	light-triggered softening	756:780	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35298857	5	51	theme	stiff	889:893	arg1	segments					904:911	alternating stiff and soft segments	877:911	alternating stiff and soft segments	877:911	Based on this, a stripe-patterned hydrogel with alternating stiff and soft segments can be fabricated through photopatterning.					
35298857	8	52	theme	metal	1473:1477	arg1	ions					1479:1482	metal ions	1473:1482	metal ions	1473:1482	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	8	53	theme	mechanical	1353:1362	arg1	performances					1364:1375	light-programmable mechanical performances	1334:1375	light-programmable mechanical performances	1334:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	6	54	theme	influence	1049:1057	arg1	factors					1059:1065	several influence factors	1041:1065	several influence factors	1041:1065	The modulus contrast between the stiff and soft phases can be adjusted by control of several influence factors and the maximum modulus contrast can reach up to 87 times.					
35298857	5	55	theme	stripe-patterned	846:861	arg1	hydrogel					863:870	a stripe-patterned hydrogel	844:870	a stripe-patterned hydrogel with alternating stiff and soft segments	844:911	Based on this, a stripe-patterned hydrogel with alternating stiff and soft segments can be fabricated through photopatterning.					
35298857	8	56	theme	light-programmable	1334:1351	arg1	performances					1364:1375	light-programmable mechanical performances	1334:1375	light-programmable mechanical performances	1334:1375	This approach shows great potential in the synthesis of smart hydrogels with light-programmable mechanical performances, and may be widely applicable for the hydrogels with functional groups that can coordinate with metal ions.					
35298857	4	57	theme	alginate/polyacrylamide	645:667	arg1	hydrogel					680:687	an alginate/polyacrylamide (Alg/PAAm) hydrogel	642:687	an alginate/polyacrylamide (Alg/PAAm) hydrogel	642:687	Ferric citric acid complex (Fe3+ /CA-complex) is used as a light-responsive ionic cross-linker, which can first stiffen an alginate/polyacrylamide (Alg/PAAm) hydrogel by coordinating with the Alg to form another network, then realize light-triggered softening through photoreduction of ferric ions (Fe3+ ).					
35337499	0	0	theme	mats	109:112	arg1	ability					86:92	the esophageal regeneration ability	58:92	the esophageal regeneration ability of nanofibrous mats	58:112	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	9	1	theme	promising	1555:1563	arg1	mats					1541:1544	LBL-structured nanofibrous mats	1514:1544	LBL-structured nanofibrous mats	1514:1544	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	9	1	theme	promising	1555:1563	arg1	materials					1565:1573	very promising materials	1550:1573	very promising materials for esophageal replacement to reduce the incidence of postoperative complications	1550:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	1	2	theme	potential	258:266	arg1	risk					268:271	a common potential risk	249:271	a common potential risk	249:271	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	1	2	theme	potential	258:266	arg1	infection					236:244	postoperative bacterial infection	212:244	postoperative bacterial infection	212:244	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	0	3	theme	nanofibrous	97:107	arg1	mats					109:112	nanofibrous mats	97:112	nanofibrous mats	97:112	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	9	4	theme	complications	1643:1655	arg1	incidence					1616:1624	the incidence	1612:1624	the incidence of postoperative complications	1612:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	8	5	theme	In	1341:1342	arg1	experiments					1356:1366	In vivo animal experiments	1341:1366	In vivo animal experiments	1341:1366	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	8	6	theme	nanofibrous	1399:1409	arg1	beneficial					1421:1430	beneficial	1421:1430	beneficial	1421:1430	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	8	6	theme	nanofibrous	1399:1409	arg1	mats					1411:1414	the LBL-structured nanofibrous mats	1380:1414	the LBL-structured nanofibrous mats	1380:1414	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	4	7	theme	nylon	566:570	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	7	8	theme	nanofibrous	1195:1205	arg1	mats					1207:1210	the nanofibrous mats	1191:1210	the nanofibrous mats modified by CS and COL	1191:1233	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	9	9	from	materials	1565:1573	arg1	summary					1505:1511	summary	1505:1511	summary	1505:1511	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	2	10	theme	esophageal	305:314	arg1	stents					316:321	artificial esophageal stents	294:321	artificial esophageal stents	294:321	Current research on artificial esophageal stents is lacking and less than satisfactory.					
35337499	6	11	theme	bacteria	1134:1141	arg1	inhibition					1093:1102	more than 90% inhibition	1079:1102	more than 90% inhibition of gram-positive and negative bacteria	1079:1141	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	4	12	theme	N6	575:576	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	3	13	theme	excellent	388:396	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	8	14	theme	animal	1349:1354	arg1	experiments					1356:1366	In vivo animal experiments	1341:1366	In vivo animal experiments	1341:1366	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	2	15	theme	artificial	294:303	arg1	stents					316:321	artificial esophageal stents	294:321	artificial esophageal stents	294:321	Current research on artificial esophageal stents is lacking and less than satisfactory.					
35337499	3	16	theme	Artificial	362:371	arg1	materials					373:381	Artificial materials	362:381	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time	362:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	6	17	contain	possessed	1026:1034	arg1	mats					1021:1024	the LBL-structured nanofibrous mats	990:1024	the LBL-structured nanofibrous mats	990:1024	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	6	17	contain	possessed	1026:1034	arg2	activity					1060:1067	excellent antibacterial activity	1036:1067	excellent antibacterial activity	1036:1067	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	7	18	theme	cell	1159:1162	arg1	experiments					1164:1174	cell experiments	1159:1174	cell experiments	1159:1174	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	6	19	theme	excellent	1036:1044	arg1	activity					1060:1067	excellent antibacterial activity	1036:1067	excellent antibacterial activity	1036:1067	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	4	20	theme	layer-by-layer	624:637	arg1	LBL					654:656	LBL	654:656	LBL	654:656	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	4	20	theme	layer-by-layer	624:637	arg1	self-assembly					639:651	layer-by-layer self-assembly	624:651	layer-by-layer self-assembly (LBL)	624:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	3	21	theme	cytocompatible	429:442	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	5	22	theme	LBL	959:961	arg1	modification					963:974	LBL modification	959:974	LBL modification	959:974	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	8	23	dep	In	1341:1342	arg1	vivo					1344:1347	vivo	1344:1347	vivo	1344:1347	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	0	24	theme	layer-by-layer	18:31	arg1	deposition					33:42	Chitosan/collagen layer-by-layer deposition	0:42	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.	0:113	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	7	25	theme	epithelial	1297:1306	arg1	cell					1308:1311	human esophageal epithelial cell adhesion and proliferation	1280:1338	cell	1308:1311	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	5	26	theme	composite	907:915	arg1	mats					929:932	the composite nanofibrous mats	903:932	the composite nanofibrous mats	903:932	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	7	27	theme	experiments	1164:1174	arg1	results					1148:1154	The results	1144:1154	The results of cell experiments	1144:1174	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	1	28	theme	recent	194:199	arg1	years					201:205	recent years	194:205	recent years	194:205	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	0	29	theme	Chitosan/collagen	0:16	arg1	deposition					33:42	Chitosan/collagen layer-by-layer deposition	0:42	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.	0:113	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	5	30	dep	morphology	753:762	arg1	the					741:743	the	741:743	the	741:743	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	5	31	theme	nanofibrous	917:927	arg1	mats					929:932	the composite nanofibrous mats	903:932	the composite nanofibrous mats	903:932	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	3	32	theme	same	462:465	arg1	time					467:470	the same time	458:470	the same time	458:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	3	33	theme	mechanical	398:407	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	5	34	theme	obtained	664:671	arg1	mats					685:688	The obtained nanofibrous mats	660:688	The obtained nanofibrous mats	660:688	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	7	35	theme	excellent	1239:1247	arg1	biocompatibility					1249:1264	excellent biocompatibility	1239:1264	excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation	1239:1338	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	5	36	theme	mats	929:932	arg1	properties					889:898	The mechanical properties	874:898	COL. The mechanical properties of the composite nanofibrous mats	869:932	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	9	37	theme	postoperative	1629:1641	arg1	complications					1643:1655	postoperative complications	1629:1655	postoperative complications	1629:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	5	38	theme	mats	812:815	arg1	hydrophilicity					768:781	hydrophilicity	768:781	hydrophilicity	768:781	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	5	38	theme	mats	812:815	arg1	morphology					753:762	surface morphology	745:762	surface morphology	745:762	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	5	39	theme	nanofibrous	800:810	arg1	mats					812:815	the composite nanofibrous mats	786:815	the composite nanofibrous mats	786:815	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	5	40	theme	nanofibrous	673:683	arg1	mats					685:688	The obtained nanofibrous mats	660:688	The obtained nanofibrous mats	660:688	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	5	41	theme	composite	790:798	arg1	mats					812:815	the composite nanofibrous mats	786:815	the composite nanofibrous mats	786:815	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	4	42	theme	SF	593:594	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	5	43	theme	surface	745:751	arg1	morphology					753:762	surface morphology	745:762	surface morphology	745:762	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	7	44	theme	esophageal	1286:1295	arg1	cell					1308:1311	human esophageal epithelial cell adhesion and proliferation	1280:1338	cell	1308:1311	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	9	45	theme	LBL-structured	1514:1527	arg1	mats					1541:1544	LBL-structured nanofibrous mats	1514:1544	LBL-structured nanofibrous mats	1514:1544	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	9	45	theme	LBL-structured	1514:1527	arg1	materials					1565:1573	very promising materials	1550:1573	very promising materials for esophageal replacement to reduce the incidence of postoperative complications	1550:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	3	46	contain	have	478:481	arg1	materials					373:381	Artificial materials	362:381	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time	362:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	3	46	contain	have	478:481	arg2	potential					489:497	great potential	483:497	great potential	483:497	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	4	47	theme	composite	597:605	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	1	48	theme	postoperative	212:224	arg1	risk					268:271	a common potential risk	249:271	a common potential risk	249:271	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	1	48	theme	postoperative	212:224	arg1	infection					236:244	postoperative bacterial infection	212:244	postoperative bacterial infection	212:244	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	6	49	theme	nanofibrous	1009:1019	arg1	mats					1021:1024	the LBL-structured nanofibrous mats	990:1024	the LBL-structured nanofibrous mats	990:1024	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	8	50	theme	control	1487:1493	arg1	group					1495:1499	the control group	1483:1499	the control group	1483:1499	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	3	51	with	materials	373:381	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	3	52	theme	great	483:487	arg1	potential					489:497	great potential	483:497	great potential	483:497	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	0	53	theme	regeneration	73:84	arg1	ability					86:92	the esophageal regeneration ability	58:92	the esophageal regeneration ability of nanofibrous mats	58:112	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	5	54	theme	CS	862:863	arg1	deposition					848:857	the deposition	844:857	the deposition of CS	844:863	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	8	55	theme	LBL-structured	1384:1397	arg1	beneficial					1421:1430	beneficial	1421:1430	beneficial	1421:1430	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	8	55	theme	LBL-structured	1384:1397	arg1	mats					1411:1414	the LBL-structured nanofibrous mats	1380:1414	the LBL-structured nanofibrous mats	1380:1414	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	6	56	dep	inhibition	1093:1102	arg1	%					1091:1091	%	1091:1091	%	1091:1091	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	5	57	theme	mechanical	878:887	arg1	properties					889:898	The mechanical properties	874:898	COL. The mechanical properties of the composite nanofibrous mats	869:932	The obtained nanofibrous mats were characterized, and the results indicated that the surface morphology and hydrophilicity of the composite nanofibrous mats were obviously improved by the deposition of CS and COL. The mechanical properties of the composite nanofibrous mats were also improved after LBL modification.					
35337499	0	58	theme	esophageal	62:71	arg1	ability					86:92	the esophageal regeneration ability	58:92	the esophageal regeneration ability of nanofibrous mats	58:112	Chitosan/collagen layer-by-layer deposition for improving the esophageal regeneration ability of nanofibrous mats.					
35337499	9	59	theme	nanofibrous	1529:1539	arg1	mats					1541:1544	LBL-structured nanofibrous mats	1514:1544	LBL-structured nanofibrous mats	1514:1544	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	9	59	theme	nanofibrous	1529:1539	arg1	materials					1565:1573	very promising materials	1550:1573	very promising materials for esophageal replacement to reduce the incidence of postoperative complications	1550:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	6	60	dep	%	1091:1091	arg1	90					1089:1090	90	1089:1090	90	1089:1090	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	7	61	theme	human	1280:1284	arg1	cell					1308:1311	human esophageal epithelial cell adhesion and proliferation	1280:1338	cell	1308:1311	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	1	62	theme	diverse	134:140	arg1	array					142:146	a diverse array	132:146	a diverse array of esophageal diseases	132:169	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	8	63	theme	esophageal	1450:1459	arg1	defects					1461:1467	esophageal defects	1450:1467	esophageal defects	1450:1467	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	2	64	theme	Current	274:280	arg1	research					282:289	Current research	274:289	Current research on artificial esophageal stents	274:321	Current research on artificial esophageal stents is lacking and less than satisfactory.					
35337499	6	65	theme	LBL-structured	994:1007	arg1	mats					1021:1024	the LBL-structured nanofibrous mats	990:1024	the LBL-structured nanofibrous mats	990:1024	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	1	66	theme	array	142:146	arg1	morbidity					119:127	The morbidity	115:127	The morbidity of a diverse array of esophageal diseases	115:169	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	2	67	from	research	282:289	arg1	stents					316:321	artificial esophageal stents	294:321	artificial esophageal stents	294:321	Current research on artificial esophageal stents is lacking and less than satisfactory.					
35337499	4	68	theme	/silk	578:582	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	7	69	dep	cell	1308:1311	arg1	adhesion					1313:1320	adhesion	1313:1320	adhesion	1313:1320	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	6	70	theme	negative	1125:1132	arg1	bacteria					1134:1141	gram-positive and negative bacteria	1107:1141	gram-positive and negative bacteria	1107:1141	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	6	71	theme	gram-positive	1107:1119	arg1	bacteria					1134:1141	gram-positive and negative bacteria	1107:1141	gram-positive and negative bacteria	1107:1141	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	1	72	theme	bacterial	226:234	arg1	risk					268:271	a common potential risk	249:271	a common potential risk	249:271	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	1	72	theme	bacterial	226:234	arg1	infection					236:244	postoperative bacterial infection	212:244	postoperative bacterial infection	212:244	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	8	73	theme	defects	1461:1467	arg1	healing					1439:1445	the healing	1435:1445	the healing of esophageal defects	1435:1467	In vivo animal experiments showed that the LBL-structured nanofibrous mats were beneficial to the healing of esophageal defects compared with the control group.					
35337499	6	74	theme	antibacterial	1046:1058	arg1	activity					1060:1067	excellent antibacterial activity	1036:1067	excellent antibacterial activity	1036:1067	In addition, the LBL-structured nanofibrous mats possessed excellent antibacterial activity, reaching more than 90% inhibition of gram-positive and negative bacteria.					
35337499	1	75	theme	esophageal	151:160	arg1	diseases					162:169	esophageal diseases	151:169	esophageal diseases	151:169	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	3	76	theme	antimicrobial	410:422	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	9	77	theme	esophageal	1579:1588	arg1	replacement					1590:1600	esophageal replacement	1579:1600	esophageal replacement to reduce the incidence of postoperative complications	1579:1655	In summary, LBL-structured nanofibrous mats are very promising materials for esophageal replacement to reduce the incidence of postoperative complications.					
35337499	7	78	contain	had	1235:1237	arg1	mats					1207:1210	the nanofibrous mats	1191:1210	the nanofibrous mats modified by CS and COL	1191:1233	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	7	78	contain	had	1235:1237	arg2	biocompatibility					1249:1264	excellent biocompatibility	1239:1264	excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation	1239:1338	The results of cell experiments indicated that the nanofibrous mats modified by CS and COL had excellent biocompatibility for promoting human esophageal epithelial cell adhesion and proliferation.					
35337499	4	79	theme	fibroin	584:590	arg1	nanofibers					607:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers	566:616	nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL)	566:657	In this study, chitosan (CS) and collagen (COL) were deposited on nylon 6 (N6)/silk fibroin (SF) composite nanofibers using layer-by-layer self-assembly (LBL).					
35337499	3	80	from	time	467:470	arg1	properties					444:453	excellent mechanical, antimicrobial, and cytocompatible properties	388:453	excellent mechanical, antimicrobial, and cytocompatible properties at the same time	388:470	Artificial materials with excellent mechanical, antimicrobial, and cytocompatible properties at the same time still have great potential.					
35337499	1	81	theme	diseases	162:169	arg1	array					142:146	a diverse array	132:146	a diverse array of esophageal diseases	132:169	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	1	82	theme	common	251:256	arg1	risk					268:271	a common potential risk	249:271	a common potential risk	249:271	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35337499	1	82	theme	common	251:256	arg1	infection					236:244	postoperative bacterial infection	212:244	postoperative bacterial infection	212:244	The morbidity of a diverse array of esophageal diseases has been increasing in recent years, and postoperative bacterial infection is a common potential risk.					
35290975	4	0	from	factor	604:609	arg1	bioinks					641:647	alginate-based bioinks	626:647	alginate-based bioinks	626:647	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	13	1	theme	medium	1764:1769	arg1	composition					1732:1742	the composition	1728:1742	the composition of the cell culture medium	1728:1769	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	12	2	dep	printable	1600:1608	arg1	fibroblasts					1584:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	2	dep	printable	1600:1608	arg1	using					1610:1614	using	1610:1614	using multiple nozzle sizes	1610:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	2	dep	printable	1600:1608	arg1	printable					1600:1608	printable	1600:1608	printable	1600:1608	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	14	3	theme	bioscaffolds	1923:1934	arg1	development					1953:1963	robust bioscaffolds forin vitromodel development	1916:1963	robust bioscaffolds forin vitromodel development	1916:1963	Ultimately, the study outlines a methodology for formulating a bioink that will result in robust bioscaffolds forin vitromodel development.					
35290975	6	4	dep	formulation	945:955	arg1	the					941:943	the	941:943	the	941:943	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	2	5	theme	scalable	344:351	arg1	method					370:375	a scalable, high-throughput method	342:375	a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition	342:446	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	11	6	contain	had	1514:1516	arg2	effect					1547:1552	no statistically significant effect	1518:1552	no statistically significant effect	1518:1552	In contrast, fibrinogen and nanofibril concentration had no statistically significant effect.					
35290975	11	6	contain	had	1514:1516	arg1	fibrinogen					1474:1483	fibrinogen	1474:1483	fibrinogen	1474:1483	In contrast, fibrinogen and nanofibril concentration had no statistically significant effect.					
35290975	11	6	contain	had	1514:1516	arg1	concentration					1500:1512	nanofibril concentration	1489:1512	nanofibril concentration	1489:1512	In contrast, fibrinogen and nanofibril concentration had no statistically significant effect.					
35290975	13	7	theme	degradation	1792:1802	arg1	rate					1804:1807	the degradation rate	1788:1807	the degradation rate of the hydrogel	1788:1823	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	10	8	theme	mechanical	1390:1399	arg1	integrity					1401:1409	mechanical integrity	1390:1409	mechanical integrity	1390:1409	The DoE demonstrated that mechanical integrity increased with increasing alginate concentration.					
35290975	3	9	from	terms	511:515	arg1	process					462:468	the process	458:468	the process of formulating bioinks	458:491	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	3	9	from	terms	511:515	arg1	complex					500:506	complex	500:506	complex	500:506	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	3	10	theme	bioscaffold	560:570	arg1	integrity					545:553	the mechanical integrity	530:553	the mechanical integrity of a bioscaffold and viability of cells	530:593	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	9	11	from	effects	1216:1222	arg1	bioink					1231:1236	the bioink	1227:1236	the bioink	1227:1236	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	7	12	theme	bioink	1079:1084	arg1	durability					1086:1095	bioink durability	1079:1095	bioink durability	1079:1095	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	2	13	dep	scalable	344:351	arg1	high-throughput					354:368	high-throughput	354:368	high-throughput	354:368	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	12	14	theme	cell	1671:1674	arg1	viability					1676:1684	fibroblast cell viability	1660:1684	fibroblast cell viability	1660:1684	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	6	15	theme	DoE	862:864	arg1	approach					867:874	a Design of Experiments (DoE) approach	837:874	a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink	837:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	7	16	theme	hydrogel	1055:1062	arg1	composition					1064:1074	hydrogel composition	1055:1074	hydrogel composition	1055:1074	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	14	17	theme	robust	1916:1921	arg1	development					1953:1963	robust bioscaffolds forin vitromodel development	1916:1963	robust bioscaffolds forin vitromodel development	1916:1963	Ultimately, the study outlines a methodology for formulating a bioink that will result in robust bioscaffolds forin vitromodel development.					
35290975	12	18	theme	fibroblast	1660:1669	arg1	viability					1676:1684	fibroblast cell viability	1660:1684	fibroblast cell viability	1660:1684	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	14	19	theme	forin	1936:1940	arg1	development					1953:1963	robust bioscaffolds forin vitromodel development	1916:1963	robust bioscaffolds forin vitromodel development	1916:1963	Ultimately, the study outlines a methodology for formulating a bioink that will result in robust bioscaffolds forin vitromodel development.					
35290975	7	20	theme	cell	1115:1118	arg1	viability					1120:1128	cell viability	1115:1128	cell viability	1115:1128	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	7	21	theme	composition	1064:1074	arg1	effects					1044:1050	the effects	1040:1050	the effects of hydrogel composition on bioink durability	1040:1095	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	3	22	theme	mechanical	534:543	arg1	integrity					545:553	the mechanical integrity	530:553	the mechanical integrity of a bioscaffold and viability of cells	530:593	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	10	23	theme	alginate	1437:1444	arg1	concentration					1446:1458	alginate concentration	1437:1458	alginate concentration	1437:1458	The DoE demonstrated that mechanical integrity increased with increasing alginate concentration.					
35290975	6	24	theme	Experiments	849:859	arg1	approach					867:874	a Design of Experiments (DoE) approach	837:874	a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink	837:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	13	25	theme	hydrogel	1816:1823	arg1	rate					1804:1807	the degradation rate	1788:1807	the degradation rate of the hydrogel	1788:1823	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	2	26	theme	precise	382:388	arg1	control					390:396	precise control	382:396	precise control over biomaterial scaffold and cellular deposition	382:446	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	14	27	theme	vitromodel	1942:1951	arg1	development					1953:1963	robust bioscaffolds forin vitromodel development	1916:1963	robust bioscaffolds forin vitromodel development	1916:1963	Ultimately, the study outlines a methodology for formulating a bioink that will result in robust bioscaffolds forin vitromodel development.					
35290975	7	28	from	effects	1044:1050	arg1	durability					1086:1095	bioink durability	1079:1095	bioink durability	1079:1095	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	1	29	dep	three-dimensional	148:164	arg1	3D					167:168	3D	167:168	3D	167:168	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	9	30	dep	extrudability	1273:1285	arg1	determined					1315:1324	determined	1315:1324	determined by dynamic mechanical analysis (DMA)	1315:1361	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	5	31	theme	extended	796:803	arg1	culture					812:818	extended tissue culture	796:818	extended tissue culture	796:818	It must allow cells to replace the bioscaffold with extracellular matrix (ECM), yet remain durable during extended tissue culture.					
35290975	12	32	theme	containing	1573:1582	arg1	fibroblasts					1584:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	32	theme	containing	1573:1582	arg1	using					1610:1614	using	1610:1614	using multiple nozzle sizes	1610:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	32	theme	containing	1573:1582	arg1	printable					1600:1608	printable	1600:1608	printable	1600:1608	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	3	33	from	complex	500:506	arg1	terms					511:515	terms	511:515	terms of balancing the mechanical integrity of a bioscaffold and viability of cells	511:593	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	2	34	theme	cellular	428:435	arg1	deposition					437:446	cellular deposition	428:446	cellular deposition	428:446	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	3	35	theme	viability	576:584	arg1	integrity					545:553	the mechanical integrity	530:553	the mechanical integrity of a bioscaffold and viability of cells	530:593	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	12	36	theme	nozzle	1625:1630	arg1	sizes					1632:1636	multiple nozzle sizes	1616:1636	multiple nozzle sizes	1616:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	6	37	theme	of	846:847	arg1	approach					867:874	a Design of Experiments (DoE) approach	837:874	a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink	837:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	1	38	theme	tissue	99:104	arg1	engineering					106:116	tissue engineering	99:116	tissue engineering	99:116	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	3	39	theme	formulating	473:483	arg1	bioinks					485:491	formulating bioinks	473:491	formulating bioinks	473:491	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	12	40	theme	multiple	1616:1623	arg1	sizes					1632:1636	multiple nozzle sizes	1616:1636	multiple nozzle sizes	1616:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	6	41	theme	Design	839:844	arg1	approach					867:874	a Design of Experiments (DoE) approach	837:874	a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink	837:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	1	42	theme	rapid	189:193	arg1	screening					195:203	rapid screening	189:203	rapid screening	189:203	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	13	43	theme	cell	1751:1754	arg1	medium					1764:1769	the cell culture medium	1747:1769	the cell culture medium	1747:1769	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	6	44	theme	variables	919:927	arg1	dependencies					894:905	the dependencies	890:905	the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink	890:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	12	45	theme	optimized	1559:1567	arg1	fibroblasts					1584:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	45	theme	optimized	1559:1567	arg1	using					1610:1614	using	1610:1614	using multiple nozzle sizes	1610:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	45	theme	optimized	1559:1567	arg1	printable					1600:1608	printable	1600:1608	printable	1600:1608	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	1	46	theme	screening	195:203	arg1	studies					226:232	rapid screening and characterization studies	189:232	rapid screening and characterization studies	189:232	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	0	47	theme	robust	47:52	arg1	ink					54:56	a robust ink	45:56	a robust ink for bioprinting	45:72	Design of experiments approach to developing a robust ink for bioprinting.					
35290975	6	48	theme	multiple	910:917	arg1	variables					919:927	multiple variables	910:927	multiple variables involved in the formulation and processing of an alginate-based bioink	910:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	4	49	theme	key	600:602	arg1	factor					604:609	One key factor	596:609	One key factor	596:609	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	4	49	theme	key	600:602	arg1	rate					657:660	the rate	653:660	the rate of bioscaffold dissolution	653:687	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	9	50	theme	dynamic	1329:1335	arg1	DMA					1358:1360	DMA	1358:1360	DMA	1358:1360	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	9	50	theme	dynamic	1329:1335	arg1	analysis					1348:1355	dynamic mechanical analysis	1329:1355	dynamic mechanical analysis (DMA)	1329:1361	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	7	51	theme	DoE	1018:1020	arg1	focus					1005:1009	The focus	1001:1009	The focus of the DoE	1001:1020	The focus of the DoE was to understand the effects of hydrogel composition on bioink durability while maintaining cell viability.					
35290975	3	52	theme	cells	589:593	arg1	bioscaffold					560:570	bioscaffold	560:570	bioscaffold	560:570	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	3	52	theme	cells	589:593	arg1	viability					576:584	viability	576:584	viability	576:584	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	13	53	theme	DMA	1687:1689	arg1	characterization					1691:1706	DMA characterization	1687:1706	DMA characterization	1687:1706	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	9	54	theme	mechanical	1337:1346	arg1	DMA					1358:1360	DMA	1358:1360	DMA	1358:1360	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	9	54	theme	mechanical	1337:1346	arg1	analysis					1348:1355	dynamic mechanical analysis	1329:1355	dynamic mechanical analysis (DMA)	1329:1361	Their effects on the bioink were then measured with respect to extrudability, strength, and stiffness as determined by dynamic mechanical analysis (DMA).					
35290975	1	55	dep	intensive	256:264	arg1	time					241:244	time	241:244	time	241:244	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	11	56	theme	significant	1535:1545	arg1	effect					1547:1552	no statistically significant effect	1518:1552	no statistically significant effect	1518:1552	In contrast, fibrinogen and nanofibril concentration had no statistically significant effect.					
35290975	3	57	theme	bioinks	485:491	arg1	process					462:468	the process	458:468	the process of formulating bioinks	458:491	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	3	57	theme	bioinks	485:491	arg1	complex					500:506	complex	500:506	complex	500:506	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	2	58	with	method	370:375	arg1	control					390:396	precise control	382:396	precise control over biomaterial scaffold and cellular deposition	382:446	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	5	59	theme	tissue	805:810	arg1	culture					812:818	extended tissue culture	796:818	extended tissue culture	796:818	It must allow cells to replace the bioscaffold with extracellular matrix (ECM), yet remain durable during extended tissue culture.					
35290975	12	60	theme	ink	1569:1571	arg1	fibroblasts					1584:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts	1555:1594	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	60	theme	ink	1569:1571	arg1	using					1610:1614	using	1610:1614	using multiple nozzle sizes	1610:1636	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	12	60	theme	ink	1569:1571	arg1	printable					1600:1608	printable	1600:1608	printable	1600:1608	The optimized ink containing fibroblasts was printable using multiple nozzle sizes while also supporting fibroblast cell viability.					
35290975	4	61	theme	bioscaffold	665:675	arg1	dissolution					677:687	bioscaffold dissolution	665:687	bioscaffold dissolution	665:687	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	1	62	theme	characterization	209:224	arg1	studies					226:232	rapid screening and characterization studies	189:232	rapid screening and characterization studies	189:232	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	5	63	theme	extracellular	742:754	arg1	matrix					756:761	extracellular matrix	742:761	extracellular matrix (ECM)	742:767	It must allow cells to replace the bioscaffold with extracellular matrix (ECM), yet remain durable during extended tissue culture.					
35290975	5	63	theme	extracellular	742:754	arg1	ECM					764:766	ECM	764:766	ECM	764:766	It must allow cells to replace the bioscaffold with extracellular matrix (ECM), yet remain durable during extended tissue culture.					
35290975	2	64	theme	biomaterial	403:413	arg1	scaffold					415:422	biomaterial scaffold	403:422	biomaterial scaffold	403:422	Bioprinting offers an opportunity to offset these limitations by providing a scalable, high-throughput method with precise control over biomaterial scaffold and cellular deposition.					
35290975	4	65	theme	alginate-based	626:639	arg1	bioinks					641:647	alginate-based bioinks	626:647	alginate-based bioinks	626:647	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	4	66	theme	dissolution	677:687	arg1	factor					604:609	One key factor	596:609	One key factor	596:609	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	4	66	theme	dissolution	677:687	arg1	rate					657:660	the rate	653:660	the rate of bioscaffold dissolution	653:687	One key factor, especially in alginate-based bioinks, is the rate of bioscaffold dissolution.					
35290975	1	67	from	advancements	83:94	arg1	engineering					106:116	tissue engineering	99:116	tissue engineering	99:116	Despite advancements in tissue engineering, the methods used to generate three-dimensional (3D)in vitromodels for rapid screening and characterization studies remain time and labor intensive.					
35290975	6	68	theme	bioink	993:998	arg1	processing					961:970	processing	961:970	processing	961:970	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	6	68	theme	bioink	993:998	arg1	formulation					945:955	formulation	945:955	formulation	945:955	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
35290975	13	69	theme	culture	1756:1762	arg1	medium					1764:1769	the cell culture medium	1747:1769	the cell culture medium	1747:1769	DMA characterization further showed that the composition of the cell culture medium did not modulate the degradation rate of the hydrogel.					
35290975	0	70	theme	experiments	10:20	arg1	Design					0:5	Design	0:5	Design of experiments	0:20	Design of experiments approach to developing a robust ink for bioprinting.					
35290975	3	71	dep	bioscaffold	560:570	arg1	a					558:558	a	558:558	a	558:558	However, the process of formulating bioinks can be complex in terms of balancing the mechanical integrity of a bioscaffold and viability of cells.					
35290975	11	72	theme	nanofibril	1489:1498	arg1	concentration					1500:1512	nanofibril concentration	1489:1512	nanofibril concentration	1489:1512	In contrast, fibrinogen and nanofibril concentration had no statistically significant effect.					
35290975	6	73	theme	alginate-based	978:991	arg1	bioink					993:998	an alginate-based bioink	975:998	an alginate-based bioink	975:998	This study uses a Design of Experiments (DoE) approach to understand the dependencies of multiple variables involved in the formulation and processing of an alginate-based bioink.					
36001265	8	0	theme	SC	1127:1128	arg1	composite					1140:1148	the SC@ZVI@CS-AA composite	1123:1148	the SC@ZVI@CS-AA composite	1123:1148	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	7	1	theme	SC	1061:1062	arg1	CS-AA					1068:1072	SC@ZVI@CS-AA	1061:1072	SC@ZVI@CS-AA	1061:1072	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	0	2	theme	composite	59:67	arg1	Preparation					0:10	Preparation	0:10	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite	0:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	0	2	theme	composite	59:67	arg1	study					73:77	study	73:77	study of its removal of groundwater Cr(VI)	73:114	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	1	3	theme	Cr	245:246	arg1	removal					234:240	the removal	230:240	the removal of Cr(VI)	230:250	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	2	4	dep	Cr	326:327	arg1	VI					329:330	VI	329:330	VI	329:330	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	6	5	theme	@	983:983	arg1	CS-AA					984:988	SC@ZVI@CS-AA	977:988	SC@ZVI@CS-AA	977:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	8	6	theme	ZVI	1130:1132	arg1	composite					1140:1148	the SC@ZVI@CS-AA composite	1123:1148	the SC@ZVI@CS-AA composite	1123:1148	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	8	7	theme	great	1157:1161	arg1	potential					1163:1171	great potential	1157:1171	great potential	1157:1171	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	3	8	theme	coexisting	508:517	arg1	ions					519:522	coexisting ions	508:522	coexisting ions	508:522	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	8	theme	coexisting	508:517	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	7	9	theme	@	1067:1067	arg1	CS-AA					1068:1072	SC@ZVI@CS-AA	1061:1072	SC@ZVI@CS-AA	1061:1072	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	6	10	dep	transform	875:883	arg1	infrared					885:892	infrared	885:892	transform infrared spectrometry	875:905	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	3	11	dep	investigated	554:565	arg1	VI					545:546	VI	545:546	VI	545:546	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	1	12	from	application	214:224	arg1	groundwater					255:265	groundwater	255:265	groundwater	255:265	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	7	13	contain	had	1074:1076	arg1	CS-AA					1068:1072	SC@ZVI@CS-AA	1061:1072	SC@ZVI@CS-AA	1061:1072	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	7	13	contain	had	1074:1076	arg2	performance					1101:1111	good cyclic adsorption performance	1078:1111	good cyclic adsorption performance	1078:1111	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	0	14	theme	removal	86:92	arg1	Preparation					0:10	Preparation	0:10	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite	0:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	0	14	theme	removal	86:92	arg1	study					73:77	study	73:77	study of its removal of groundwater Cr(VI)	73:114	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	3	15	theme	Cr	542:543	arg1	removal					531:537	the removal	527:537	the removal of Cr	527:543	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	4	16	theme	ZVI	607:609	arg1	CS-AA					611:615	SC@ZVI@CS-AA	604:615	SC@ZVI@CS-AA	604:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	4	17	theme	removal	572:578	arg1	efficiency					580:589	The removal efficiency	568:589	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA	568:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	6	18	theme	electron	812:819	arg1	microscopy					821:830	scanning electron microscopy	803:830	scanning electron microscopy	803:830	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	0	19	theme	ZVI	33:35	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	4	20	theme	@	606:606	arg1	CS-AA					611:615	SC@ZVI@CS-AA	604:615	SC@ZVI@CS-AA	604:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	6	21	theme	synchronous	912:922	arg1	analysis					932:939	synchronous thermal analysis	912:939	synchronous thermal analysis	912:939	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	4	22	dep	Cr	594:595	arg1	VI					597:598	VI	597:598	VI	597:598	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	7	23	theme	good	1078:1081	arg1	performance					1101:1111	good cyclic adsorption performance	1078:1111	good cyclic adsorption performance	1078:1111	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	6	24	theme	SC	977:978	arg1	CS-AA					984:988	SC@ZVI@CS-AA	977:988	SC@ZVI@CS-AA	977:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	2	25	theme	pseudo-second-order	348:366	arg1	model					368:372	a pseudo-second-order model	346:372	a pseudo-second-order model	346:372	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	8	26	theme	Cr	1195:1196	arg1	remediation					1180:1190	the remediation	1176:1190	the remediation of Cr(VI)-contaminated groundwater	1176:1225	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	1	27	dep	Cr	245:246	arg1	VI					248:249	VI	248:249	VI	248:249	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	4	28	theme	@	610:610	arg1	CS-AA					611:615	SC@ZVI@CS-AA	604:615	SC@ZVI@CS-AA	604:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	6	29	theme	ZVI	980:982	arg1	CS-AA					984:988	SC@ZVI@CS-AA	977:988	SC@ZVI@CS-AA	977:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	3	30	from	effects	438:444	arg1	removal					531:537	the removal	527:537	the removal of Cr	527:543	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	8	31	theme	@	1129:1129	arg1	composite					1140:1148	the SC@ZVI@CS-AA composite	1123:1148	the SC@ZVI@CS-AA composite	1123:1148	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	0	32	theme	sulfonated	17:26	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	6	33	dep	Cr	967:968	arg1	VI					970:971	VI	970:971	VI	970:971	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	0	34	theme	groundwater	97:107	arg1	Cr					109:110	groundwater Cr	97:110	groundwater Cr(VI)	97:114	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	6	35	theme	Cr	967:968	arg1	mechanism					954:962	the removal mechanism	942:962	the removal mechanism of Cr(VI) by SC@ZVI@CS-AA	942:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	7	36	theme	cyclic	1083:1088	arg1	performance					1101:1111	good cyclic adsorption performance	1078:1111	good cyclic adsorption performance	1078:1111	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	1	37	theme	new	137:139	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	37	theme	new	137:139	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	2	38	theme	ZVI	312:314	arg1	CS-AA					316:320	SC@ZVI@CS-AA	309:320	SC@ZVI@CS-AA	309:320	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	6	39	theme	thermal	924:930	arg1	analysis					932:939	synchronous thermal analysis	912:939	synchronous thermal analysis	912:939	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	3	40	theme	@	485:485	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	40	theme	@	485:485	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	7	41	theme	adsorption	1090:1099	arg1	performance					1101:1111	good cyclic adsorption performance	1078:1111	good cyclic adsorption performance	1078:1111	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	2	42	theme	SC	309:310	arg1	CS-AA					316:320	SC@ZVI@CS-AA	309:320	SC@ZVI@CS-AA	309:320	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	0	43	theme	@	32:32	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	8	44	dep	Cr	1195:1196	arg1	VI					1198:1199	VI	1198:1199	VI	1198:1199	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	8	44	dep	Cr	1195:1196	arg1	groundwater					1215:1225	-contaminated groundwater	1201:1225	Cr(VI)-contaminated groundwater	1195:1225	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	3	45	theme	ZVI	486:488	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	45	theme	ZVI	486:488	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	46	theme	material	449:456	arg1	ions					519:522	coexisting ions	508:522	coexisting ions	508:522	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	46	theme	material	449:456	arg1	pH					466:467	pH	466:467	pH	466:467	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	46	theme	material	449:456	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	46	theme	material	449:456	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	46	theme	material	449:456	arg1	temperature					470:480	temperature	470:480	temperature	470:480	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	1	47	theme	adsorbent	151:159	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	47	theme	adsorbent	151:159	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	0	48	theme	coal	28:31	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	8	49	theme	-contaminated	1201:1213	arg1	groundwater					1215:1225	-contaminated groundwater	1201:1225	Cr(VI)-contaminated groundwater	1195:1225	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	2	50	theme	adsorption	383:392	arg1	process					394:400	the adsorption process	379:400	the adsorption process	379:400	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	5	51	dep	Cr	736:737	arg1	VI					739:740	VI	739:740	VI	739:740	Thermodynamically, the adsorption of Cr(VI) proceeded spontaneously above 35 °C (ΔGθ < 0).					
36001265	2	52	theme	@	315:315	arg1	CS-AA					316:320	SC@ZVI@CS-AA	309:320	SC@ZVI@CS-AA	309:320	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	0	53	theme	@	36:36	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	3	54	theme	SC	483:484	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	54	theme	SC	483:484	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	4	55	theme	SC	604:605	arg1	CS-AA					611:615	SC@ZVI@CS-AA	604:615	SC@ZVI@CS-AA	604:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	0	56	theme	Cr	109:110	arg1	removal					86:92	its removal	82:92	its removal of groundwater Cr(VI)	82:114	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	6	57	theme	@	979:979	arg1	CS-AA					984:988	SC@ZVI@CS-AA	977:988	SC@ZVI@CS-AA	977:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	8	58	theme	CS-AA	1134:1138	arg1	composite					1140:1148	the SC@ZVI@CS-AA composite	1123:1148	the SC@ZVI@CS-AA composite	1123:1148	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	6	59	dep	Fourier	867:873	arg1	transform					875:883	transform	875:883	transform infrared spectrometry	875:905	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	6	60	theme	electrostatic	1008:1020	arg1	attraction					1022:1031	electrostatic attraction	1008:1031	electrostatic attraction	1008:1031	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	7	61	theme	@	1063:1063	arg1	CS-AA					1068:1072	SC@ZVI@CS-AA	1061:1072	SC@ZVI@CS-AA	1061:1072	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	5	62	theme	Cr	736:737	arg1	adsorption					722:731	the adsorption	718:731	the adsorption of Cr(VI)	718:741	Thermodynamically, the adsorption of Cr(VI) proceeded spontaneously above 35 °C (ΔGθ < 0).					
36001265	3	63	theme	ratios	458:463	arg1	effects					438:444	The effects	434:444	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr	434:543	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	1	64	theme	SC	162:163	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	64	theme	SC	162:163	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	8	65	theme	@	1133:1133	arg1	composite					1140:1148	the SC@ZVI@CS-AA composite	1123:1148	the SC@ZVI@CS-AA composite	1123:1148	Overall, the SC@ZVI@CS-AA composite showed great potential in the remediation of Cr(VI)-contaminated groundwater.					
36001265	3	66	theme	@	489:489	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	66	theme	@	489:489	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	7	67	theme	ZVI	1064:1066	arg1	CS-AA					1068:1072	SC@ZVI@CS-AA	1061:1072	SC@ZVI@CS-AA	1061:1072	In addition, SC@ZVI@CS-AA had good cyclic adsorption performance.					
36001265	6	68	theme	X-ray	833:837	arg1	spectroscopy					853:864	X-ray photoelectron spectroscopy	833:864	X-ray photoelectron spectroscopy	833:864	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	1	69	theme	@	164:164	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	69	theme	@	164:164	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	0	70	theme	acid	54:57	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	3	71	theme	CS-AA	490:494	arg1	ratios					458:463	material ratios	449:463	material ratios	449:463	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	3	71	theme	CS-AA	490:494	arg1	dosage					496:501	SC@ZVI@CS-AA dosage	483:501	SC@ZVI@CS-AA dosage	483:501	The effects of material ratios, pH, temperature, SC@ZVI@CS-AA dosage, and coexisting ions on the removal of Cr(VI) were investigated.					
36001265	6	72	theme	removal	946:952	arg1	mechanism					954:962	the removal mechanism	942:962	the removal mechanism of Cr(VI) by SC@ZVI@CS-AA	942:988	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	2	73	theme	@	311:311	arg1	CS-AA					316:320	SC@ZVI@CS-AA	309:320	SC@ZVI@CS-AA	309:320	The interaction between SC@ZVI@CS-AA and Cr(VI) conformed to a pseudo-second-order model, and the adsorption process was dominated by chemisorption.					
36001265	6	74	theme	photoelectron	839:851	arg1	spectroscopy					853:864	X-ray photoelectron spectroscopy	833:864	X-ray photoelectron spectroscopy	833:864	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	6	75	theme	scanning	803:810	arg1	microscopy					821:830	scanning electron microscopy	803:830	scanning electron microscopy	803:830	According to scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectrometry, and synchronous thermal analysis, the removal mechanism of Cr(VI) by SC@ZVI@CS-AA was attributed to electrostatic attraction and reduction.					
36001265	1	76	theme	ZVI	165:167	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	76	theme	ZVI	165:167	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	0	77	theme	chitosan-acrylic	37:52	arg1	composite					59:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	a sulfonated coal@ZVI@chitosan-acrylic acid composite	15:67	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	4	78	theme	Cr	594:595	arg1	efficiency					580:589	The removal efficiency	568:589	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA	568:615	The removal efficiency of Cr(VI) by SC@ZVI@CS-AA reached 95%, and the reaction was significantly inhibited when SO42- was present.					
36001265	0	79	dep	Cr	109:110	arg1	VI					112:113	VI	112:113	VI	112:113	Preparation of a sulfonated coal@ZVI@chitosan-acrylic acid composite and study of its removal of groundwater Cr(VI).					
36001265	1	80	theme	@	168:168	arg1	composite					141:149	a new composite adsorbent	135:159	a new composite adsorbent (SC@ZVI@CS-AA)	135:174	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
36001265	1	80	theme	@	168:168	arg1	CS-AA					169:173	SC@ZVI@CS-AA	162:173	SC@ZVI@CS-AA	162:173	In this research, a new composite adsorbent (SC@ZVI@CS-AA) was designed and synthesized, and its application for the removal of Cr(VI) in groundwater was investigated.					
35581085	7	0	theme	CSMA/β-TCP	1120:1129	arg1	hydrogel					1141:1148	the CSMA/β-TCP composite hydrogel	1116:1148	the CSMA/β-TCP composite hydrogel	1116:1148	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	1	1	theme	clinical	149:156	arg1	practice					158:165	clinical practice	149:165	clinical practice	149:165	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	3	2	theme	chitosan	329:336	arg1	methacryloyl					338:349	chitosan methacryloyl	329:349	chitosan methacryloyl (CSMA)	329:356	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	3	2	theme	chitosan	329:336	arg1	CSMA					352:355	CSMA	352:355	CSMA	352:355	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	7	3	theme	composite	1131:1139	arg1	hydrogel					1141:1148	the CSMA/β-TCP composite hydrogel	1116:1148	the CSMA/β-TCP composite hydrogel	1116:1148	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	2	4	theme	compatibility	299:311	arg1	requirements					254:265	the dual requirements	245:265	the dual requirements of mechanical strength and cell compatibility	245:311	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	5	5	theme	pathway	930:936	arg1	mechanism					897:905	the regulatory mechanism	882:905	the regulatory mechanism of the Hippo signaling pathway	882:936	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	4	6	theme	bone	601:604	arg1	BMSCs					637:641	BMSCs	637:641	BMSCs	637:641	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	6	theme	bone	601:604	arg1	cells					630:634	bone marrow mesenchymal stem cells	601:634	bone marrow mesenchymal stem cells (BMSCs)	601:642	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	3	7	theme	β-tricalcium	362:373	arg1	β-TCP					386:390	β-TCP	386:390	β-TCP	386:390	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	3	7	theme	β-tricalcium	362:373	arg1	phosphate					375:383	β-tricalcium phosphate	362:383	β-tricalcium phosphate (β-TCP)	362:391	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	1	8	from	problem	138:144	arg1	practice					158:165	clinical practice	149:165	clinical practice	149:165	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	2	9	theme	cell	294:297	arg1	compatibility					299:311	cell compatibility	294:311	cell compatibility	294:311	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	3	10	theme	strong	483:488	arg1	properties					501:510	strong mechanical properties	483:510	strong mechanical properties contributing to bone regeneration	483:544	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	3	11	contain	has	479:481	arg1	hydrogel					463:470	the CSMA/β-TCP composite hydrogel	438:470	the CSMA/β-TCP composite hydrogel	438:470	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	3	11	contain	has	479:481	arg2	properties					501:510	strong mechanical properties	483:510	strong mechanical properties contributing to bone regeneration	483:544	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	7	12	theme	immense	1095:1101	arg1	potential					1103:1111	the immense potential	1091:1111	the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy	1091:1177	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	6	13	contain	has	1012:1014	arg1	CSMA/β-TCP					1001:1010	CSMA/β-TCP	1001:1010	CSMA/β-TCP	1001:1010	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	6	13	contain	has	1012:1014	arg2	regeneration					1051:1062	bone regeneration	1046:1062	bone regeneration	1046:1062	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	6	13	contain	has	1012:1014	arg2	biocompatibility					1025:1040	adequate biocompatibility	1016:1040	adequate biocompatibility	1016:1040	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	1	14	theme	High-efficiency	76:90	arg1	problem					138:144	a pressing problem	127:144	a pressing problem in clinical practice	127:165	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	1	14	theme	High-efficiency	76:90	arg1	repair					92:97	High-efficiency repair	76:97	High-efficiency repair of critical bone defects	76:122	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	3	15	theme	mechanical	490:499	arg1	properties					501:510	strong mechanical properties	483:510	strong mechanical properties contributing to bone regeneration	483:544	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	3	16	theme	CSMA/β-TCP	442:451	arg1	hydrogel					463:470	the CSMA/β-TCP composite hydrogel	438:470	the CSMA/β-TCP composite hydrogel	438:470	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	0	17	theme	enhanced	13:20	arg1	scaffold					41:48	Mechanically enhanced composite hydrogel scaffold	0:48	Mechanically enhanced composite hydrogel scaffold for in situ bone	0:65	Mechanically enhanced composite hydrogel scaffold for in situ bone repairs.					
35581085	7	18	from	potential	1103:1111	arg1	therapy					1171:1177	bone regeneration therapy	1153:1177	bone regeneration therapy	1153:1177	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	5	19	theme	Hippo	914:918	arg1	pathway					930:936	the Hippo signaling pathway	910:936	the Hippo signaling pathway	910:936	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	4	20	theme	nodular	744:750	arg1	deposition					752:761	the nodular deposition	740:761	the nodular deposition of calcium	740:772	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	0	21	theme	hydrogel	32:39	arg1	scaffold					41:48	Mechanically enhanced composite hydrogel scaffold	0:48	Mechanically enhanced composite hydrogel scaffold for in situ bone	0:65	Mechanically enhanced composite hydrogel scaffold for in situ bone repairs.					
35581085	1	22	theme	critical	102:109	arg1	defects					116:122	critical bone defects	102:122	critical bone defects	102:122	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	5	23	theme	proteins	816:823	arg1	Meanwhile					775:783	Meanwhile	775:783	Meanwhile	775:783	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	23	theme	proteins	816:823	arg1	expressions					790:800	the expressions	786:800	the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin)	786:859	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	0	24	theme	composite	22:30	arg1	scaffold					41:48	Mechanically enhanced composite hydrogel scaffold	0:48	Mechanically enhanced composite hydrogel scaffold for in situ bone	0:65	Mechanically enhanced composite hydrogel scaffold for in situ bone repairs.					
35581085	2	25	theme	most	177:180	arg1	materials					205:213	most biological replacement materials	177:213	most biological replacement materials	177:213	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	1	26	theme	bone	111:114	arg1	defects					116:122	critical bone defects	102:122	critical bone defects	102:122	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	7	27	theme	bone	1153:1156	arg1	therapy					1171:1177	bone regeneration therapy	1153:1177	bone regeneration therapy	1153:1177	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	5	28	theme	regulatory	886:895	arg1	mechanism					897:905	the regulatory mechanism	882:905	the regulatory mechanism of the Hippo signaling pathway	882:936	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	3	29	theme	composite	453:461	arg1	hydrogel					463:470	the CSMA/β-TCP composite hydrogel	438:470	the CSMA/β-TCP composite hydrogel	438:470	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	7	30	theme	regeneration	1158:1169	arg1	therapy					1171:1177	bone regeneration therapy	1153:1177	bone regeneration therapy	1153:1177	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	0	31	dep	in	54:55	arg1	situ					57:60	situ	57:60	situ	57:60	Mechanically enhanced composite hydrogel scaffold for in situ bone repairs.					
35581085	6	32	theme	adequate	1016:1023	arg1	biocompatibility					1025:1040	adequate biocompatibility	1016:1040	adequate biocompatibility	1016:1040	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	7	33	theme	hydrogel	1141:1148	arg1	potential					1103:1111	the immense potential	1091:1111	the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy	1091:1177	These results demonstrate the immense potential of the CSMA/β-TCP composite hydrogel in bone regeneration therapy.					
35581085	5	34	theme	osteogenic	805:814	arg1	ALP					826:828	ALP	826:828	ALP	826:828	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	34	theme	osteogenic	805:814	arg1	proteins					816:823	osteogenic proteins	805:823	osteogenic proteins (ALP, osteocalcin, and osteopontin)	805:859	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	34	theme	osteogenic	805:814	arg1	osteocalcin					831:841	osteocalcin	831:841	osteocalcin	831:841	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	34	theme	osteogenic	805:814	arg1	osteopontin					848:858	osteopontin	848:858	osteopontin	848:858	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	1	35	theme	defects	116:122	arg1	problem					138:144	a pressing problem	127:144	a pressing problem in clinical practice	127:165	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	1	35	theme	defects	116:122	arg1	repair					92:97	High-efficiency repair	76:97	High-efficiency repair of critical bone defects	76:122	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	0	36	theme	in	54:55	arg1	bone					62:65	in situ bone	54:65	in situ bone	54:65	Mechanically enhanced composite hydrogel scaffold for in situ bone repairs.					
35581085	4	37	theme	alkaline	700:707	arg1	phosphatase					709:719	alkaline phosphatase	700:719	alkaline phosphatase (ALP)	700:725	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	37	theme	alkaline	700:707	arg1	ALP					722:724	ALP	722:724	ALP	722:724	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	38	theme	phosphatase	709:719	arg1	expression					686:695	the expression	682:695	the expression of alkaline phosphatase (ALP)	682:725	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	2	39	theme	mechanical	270:279	arg1	strength					281:288	mechanical strength	270:288	mechanical strength	270:288	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	5	40	theme	signaling	920:928	arg1	pathway					930:936	the Hippo signaling pathway	910:936	the Hippo signaling pathway	910:936	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	4	41	theme	mesenchymal	613:623	arg1	BMSCs					637:641	BMSCs	637:641	BMSCs	637:641	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	41	theme	mesenchymal	613:623	arg1	cells					630:634	bone marrow mesenchymal stem cells	601:634	bone marrow mesenchymal stem cells (BMSCs)	601:642	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	2	42	theme	strength	281:288	arg1	requirements					254:265	the dual requirements	245:265	the dual requirements of mechanical strength and cell compatibility	245:311	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	2	43	theme	replacement	193:203	arg1	materials					205:213	most biological replacement materials	177:213	most biological replacement materials	177:213	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	4	44	theme	calcium	766:772	arg1	deposition					752:761	the nodular deposition	740:761	the nodular deposition of calcium	740:772	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	1	45	theme	pressing	129:136	arg1	repair					92:97	High-efficiency repair	76:97	High-efficiency repair of critical bone defects	76:122	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	1	45	theme	pressing	129:136	arg1	problem					138:144	a pressing problem	127:144	a pressing problem in clinical practice	127:165	High-efficiency repair of critical bone defects is a pressing problem in clinical practice.					
35581085	4	46	theme	marrow	606:611	arg1	BMSCs					637:641	BMSCs	637:641	BMSCs	637:641	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	46	theme	marrow	606:611	arg1	cells					630:634	bone marrow mesenchymal stem cells	601:634	bone marrow mesenchymal stem cells (BMSCs)	601:642	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	2	47	theme	biological	182:191	arg1	materials					205:213	most biological replacement materials	177:213	most biological replacement materials	177:213	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	5	48	dep	proteins	816:823	arg1	ALP					826:828	ALP	826:828	ALP	826:828	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	48	dep	proteins	816:823	arg1	proteins					816:823	osteogenic proteins	805:823	osteogenic proteins (ALP, osteocalcin, and osteopontin)	805:859	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	48	dep	proteins	816:823	arg1	osteocalcin					831:841	osteocalcin	831:841	osteocalcin	831:841	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	5	48	dep	proteins	816:823	arg1	osteopontin					848:858	osteopontin	848:858	osteopontin	848:858	Meanwhile, the expressions of osteogenic proteins (ALP, osteocalcin, and osteopontin) were upregulated and the regulatory mechanism of the Hippo signaling pathway was verified.					
35581085	6	49	theme	bone	1046:1049	arg1	regeneration					1051:1062	bone regeneration	1046:1062	bone regeneration	1046:1062	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	3	50	theme	bone	528:531	arg1	regeneration					533:544	bone regeneration	528:544	bone regeneration	528:544	In this study, chitosan methacryloyl (CSMA) and β-tricalcium phosphate (β-TCP) were subjected to photo-crosslinking to form the CSMA/β-TCP composite hydrogel, which has strong mechanical properties contributing to bone regeneration.					
35581085	4	51	theme	cells	630:634	arg1	morphology					587:596	the morphology	583:596	the morphology of bone marrow mesenchymal stem cells (BMSCs)	583:642	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	6	52	theme	animal	962:967	arg1	experiments					969:979	animal experiments	962:979	animal experiments	962:979	Moreover, animal experiments have confirmed that CSMA/β-TCP has adequate biocompatibility and bone regeneration.					
35581085	2	53	theme	dual	249:252	arg1	requirements					254:265	the dual requirements	245:265	the dual requirements of mechanical strength and cell compatibility	245:311	However, most biological replacement materials do not simultaneously satisfy the dual requirements of mechanical strength and cell compatibility.					
35581085	4	54	theme	stem	625:628	arg1	BMSCs					637:641	BMSCs	637:641	BMSCs	637:641	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
35581085	4	54	theme	stem	625:628	arg1	cells					630:634	bone marrow mesenchymal stem cells	601:634	bone marrow mesenchymal stem cells (BMSCs)	601:642	In addition, its scaffold can alter the morphology of bone marrow mesenchymal stem cells (BMSCs), promote their proliferation, enhance the expression of alkaline phosphatase (ALP), and augment the nodular deposition of calcium.					
37348580	7	0	theme	recyclable	1069:1078	arg1	efficiency					1080:1089	excellent recyclable efficiency	1059:1089	excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions	1059:1152	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
37348580	6	1	theme	II	962:963	arg1	ions					966:969	chemical coordination Pb(II) ions	937:969	chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite	937:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	2	2	theme	Pb	469:470	arg1	ions					476:479	Pb(II) ions	469:479	Pb(II) ions	469:479	Its removal ability of Pb(II) ions from aqueous solution was investigated.					
37348580	2	3	from	solution	494:501	arg1	ability					458:464	Its removal ability	446:464	Its removal ability of Pb(II) ions from aqueous solution	446:501	Its removal ability of Pb(II) ions from aqueous solution was investigated.					
37348580	0	4	from	solution	150:157	arg1	removal					114:120	removal	114:120	removal of Pb(II) ions from aqueous solution	114:157	Chitosan cross-linked and grafted with epichlorohydrin and 2,4-dichlorobenzaldehyde as an efficient adsorbent for removal of Pb(II) ions from aqueous solution.					
37348580	3	5	theme	co-existing	627:637	arg1	ions					639:642	co-existing ions	627:642	co-existing ions	627:642	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	4	6	theme	ions	687:690	arg1	170 mg/g					696:703	170 mg/g	696:703	170 mg/g	696:703	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	4	6	theme	ions	687:690	arg1	capacity					668:675	The maximum adsorption capacity	645:675	The maximum adsorption capacity of Pb(II) ions	645:690	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	2	7	theme	aqueous	486:492	arg1	solution					494:501	aqueous solution	486:501	aqueous solution	486:501	Its removal ability of Pb(II) ions from aqueous solution was investigated.					
37348580	7	8	theme	other	1131:1135	arg1	ions					1149:1152	other heavy metal ions	1131:1152	other heavy metal ions	1131:1152	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
37348580	0	9	theme	Pb	125:126	arg1	ions					132:135	Pb(II) ions	125:135	Pb(II) ions	125:135	Chitosan cross-linked and grafted with epichlorohydrin and 2,4-dichlorobenzaldehyde as an efficient adsorbent for removal of Pb(II) ions from aqueous solution.					
37348580	5	10	theme	single-layer	792:803	arg1	model					823:827	single-layer Langmuir isotherm model	792:827	single-layer Langmuir isotherm model	792:827	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	4	11	theme	Pb	680:681	arg1	ions					687:690	Pb(II) ions	680:690	Pb(II) ions	680:690	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	5	12	theme	kinetics	863:870	arg1	model					872:876	the pseudo-second-order (PSO) kinetics model	833:876	the pseudo-second-order (PSO) kinetics model	833:876	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	6	13	theme	chemical	937:944	arg1	ions					966:969	chemical coordination Pb(II) ions	937:969	chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite	937:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	1	14	theme	Epichlorohydrin-modified	160:183	arg1	CS/24Cl/ECH					217:227	CS/24Cl/ECH	217:227	CS/24Cl/ECH	217:227	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	14	theme	Epichlorohydrin-modified	160:183	arg1	composite					206:214	Epichlorohydrin-modified chitosan-Schiff base composite	160:214	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction	160:262	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	2	15	theme	ions	476:479	arg1	ability					458:464	Its removal ability	446:464	Its removal ability of Pb(II) ions from aqueous solution	446:501	Its removal ability of Pb(II) ions from aqueous solution was investigated.					
37348580	1	16	theme	Differential	366:377	arg1	DSC					401:403	DSC	401:403	DSC	401:403	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	16	theme	Differential	366:377	arg1	calorimetry					388:398	Differential scanning calorimetry	366:398	Differential scanning calorimetry (DSC)	366:404	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	6	17	theme	CS/24Cl/ECH	1011:1021	arg1	composite					1023:1031	CS/24Cl/ECH composite	1011:1031	CS/24Cl/ECH composite	1011:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	1	18	theme	chitosan-Schiff	185:199	arg1	CS/24Cl/ECH					217:227	CS/24Cl/ECH	217:227	CS/24Cl/ECH	217:227	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	18	theme	chitosan-Schiff	185:199	arg1	composite					206:214	Epichlorohydrin-modified chitosan-Schiff base composite	160:214	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction	160:262	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	19	theme	scanning	379:386	arg1	DSC					401:403	DSC	401:403	DSC	401:403	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	19	theme	scanning	379:386	arg1	calorimetry					388:398	Differential scanning calorimetry	366:398	Differential scanning calorimetry (DSC)	366:404	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	6	20	theme	Pb	959:960	arg1	ions					966:969	chemical coordination Pb(II) ions	937:969	chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite	937:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	3	21	theme	CS/24-Cl/ECH	596:607	arg1	ions					639:642	co-existing ions	627:642	co-existing ions	627:642	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	3	21	theme	CS/24-Cl/ECH	596:607	arg1	dose					588:591	dose	588:591	dose of CS/24-Cl/ECH	588:607	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	3	21	theme	CS/24-Cl/ECH	596:607	arg1	pH					584:585	different initial pH	566:585	different initial pH	566:585	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	3	21	theme	CS/24-Cl/ECH	596:607	arg1	time					618:621	contact time	610:621	contact time	610:621	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	3	22	theme	Pb	539:540	arg1	ions					546:549	Pb(II) ions	539:549	Pb(II) ions	539:549	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	1	23	theme	base	201:204	arg1	CS/24Cl/ECH					217:227	CS/24Cl/ECH	217:227	CS/24Cl/ECH	217:227	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	23	theme	base	201:204	arg1	composite					206:214	Epichlorohydrin-modified chitosan-Schiff base composite	160:214	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction	160:262	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	5	24	theme	absorption	728:737	arg1	results					739:745	the absorption results	724:745	the absorption results	724:745	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	1	25	theme	Infra-Red	302:310	arg1	spectroscopy					312:323	Infra-Red spectroscopy	302:323	Infra-Red spectroscopy (FT-IR)	302:331	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	25	theme	Infra-Red	302:310	arg1	FT-IR					326:330	FT-IR	326:330	FT-IR	326:330	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	5	26	theme	pseudo-second-order	837:855	arg1	model					872:876	the pseudo-second-order (PSO) kinetics model	833:876	the pseudo-second-order (PSO) kinetics model	833:876	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	6	27	theme	composite	1023:1031	arg1	surface					1000:1006	the surface	996:1006	the surface of CS/24Cl/ECH composite	996:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	5	28	dep	pseudo-second-order	837:855	arg1	PSO					858:860	PSO	858:860	PSO	858:860	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	6	29	theme	active	980:985	arg1	sites					987:991	the active sites	976:991	the active sites on the surface of CS/24Cl/ECH composite	976:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	0	30	theme	ions	132:135	arg1	removal					114:120	removal	114:120	removal of Pb(II) ions from aqueous solution	114:157	Chitosan cross-linked and grafted with epichlorohydrin and 2,4-dichlorobenzaldehyde as an efficient adsorbent for removal of Pb(II) ions from aqueous solution.					
37348580	7	31	theme	potential	1109:1117	arg1	sorbent					1119:1125	potential sorbent	1109:1125	potential sorbent	1109:1125	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
37348580	3	32	theme	ions	546:549	arg1	adsorption					525:534	The adsorption	521:534	The adsorption of Pb(II) ions	521:549	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	6	33	theme	ions	914:917	arg1	mechanism					894:902	The absorption mechanism	879:902	The absorption mechanism of Pb(II) ions	879:917	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	5	34	theme	Pb	766:767	arg1	ions					773:776	Pb(II) ions	766:776	Pb(II) ions	766:776	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	6	35	theme	absorption	883:892	arg1	mechanism					894:902	The absorption mechanism	879:902	The absorption mechanism of Pb(II) ions	879:917	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	6	36	theme	Pb	907:908	arg1	ions					914:917	Pb(II) ions	907:917	Pb(II) ions	907:917	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	2	37	theme	removal	450:456	arg1	ability					458:464	Its removal ability	446:464	Its removal ability of Pb(II) ions from aqueous solution	446:501	Its removal ability of Pb(II) ions from aqueous solution was investigated.					
37348580	0	38	theme	aqueous	142:148	arg1	solution					150:157	aqueous solution	142:157	aqueous solution	142:157	Chitosan cross-linked and grafted with epichlorohydrin and 2,4-dichlorobenzaldehyde as an efficient adsorbent for removal of Pb(II) ions from aqueous solution.					
37348580	7	39	theme	heavy	1137:1141	arg1	ions					1149:1152	other heavy metal ions	1131:1152	other heavy metal ions	1131:1152	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
37348580	6	40	with	ions	966:969	arg1	sites					987:991	the active sites	976:991	the active sites on the surface of CS/24Cl/ECH composite	976:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	4	41	theme	maximum	649:655	arg1	170 mg/g					696:703	170 mg/g	696:703	170 mg/g	696:703	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	4	41	theme	maximum	649:655	arg1	capacity					668:675	The maximum adsorption capacity	645:675	The maximum adsorption capacity of Pb(II) ions	645:690	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	3	42	theme	contact	610:616	arg1	time					618:621	contact time	610:621	contact time	610:621	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	1	43	dep	Fourier	284:290	arg1	transform					292:300	transform	292:300	transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM)	292:443	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	6	44	from	sites	987:991	arg1	surface					1000:1006	the surface	996:1006	the surface of CS/24Cl/ECH composite	996:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	5	45	theme	Langmuir	805:812	arg1	model					823:827	single-layer Langmuir isotherm model	792:827	single-layer Langmuir isotherm model	792:827	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	1	46	theme	X-ray	334:338	arg1	XRD					360:362	XRD	360:362	XRD	360:362	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	46	theme	X-ray	334:338	arg1	diffraction					347:357	X-ray powder diffraction	334:357	X-ray powder diffraction (XRD)	334:363	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	47	theme	Scanning	410:417	arg1	SEM					440:442	SEM	440:442	SEM	440:442	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	47	theme	Scanning	410:417	arg1	microscope					428:437	Scanning electron microscope	410:437	Scanning electron microscope (SEM)	410:443	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	3	48	theme	different	566:574	arg1	pH					584:585	different initial pH	566:585	different initial pH	566:585	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	5	49	theme	isotherm	814:821	arg1	model					823:827	single-layer Langmuir isotherm model	792:827	single-layer Langmuir isotherm model	792:827	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	1	50	theme	electron	419:426	arg1	SEM					440:442	SEM	440:442	SEM	440:442	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	50	theme	electron	419:426	arg1	microscope					428:437	Scanning electron microscope	410:437	Scanning electron microscope (SEM)	410:443	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	3	51	theme	initial	576:582	arg1	pH					584:585	different initial pH	566:585	different initial pH	566:585	The adsorption of Pb(II) ions carried out at different initial pH, dose of CS/24-Cl/ECH, contact time and co-existing ions.					
37348580	4	52	theme	adsorption	657:666	arg1	170 mg/g					696:703	170 mg/g	696:703	170 mg/g	696:703	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	4	52	theme	adsorption	657:666	arg1	capacity					668:675	The maximum adsorption capacity	645:675	The maximum adsorption capacity of Pb(II) ions	645:690	The maximum adsorption capacity of Pb(II) ions was 170 mg/g.					
37348580	5	53	theme	ions	773:776	arg1	adsorption					752:761	the adsorption	748:761	the adsorption of Pb(II) ions	748:776	Finally, based on the absorption results, the adsorption of Pb(II) ions was fitted by single-layer Langmuir isotherm model and the pseudo-second-order (PSO) kinetics model.					
37348580	6	54	theme	coordination	946:957	arg1	ions					966:969	chemical coordination Pb(II) ions	937:969	chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite	937:1031	The absorption mechanism of Pb(II) ions was controlled by chemical coordination Pb(II) ions with the active sites on the surface of CS/24Cl/ECH composite.					
37348580	1	55	theme	one-pot	247:253	arg1	reaction					255:262	the one-pot reaction	243:262	the one-pot reaction	243:262	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	56	theme	powder	340:345	arg1	XRD					360:362	XRD	360:362	XRD	360:362	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	1	56	theme	powder	340:345	arg1	diffraction					347:357	X-ray powder diffraction	334:357	X-ray powder diffraction (XRD)	334:363	Epichlorohydrin-modified chitosan-Schiff base composite (CS/24Cl/ECH) prepared via the one-pot reaction as characterized by Fourier transform Infra-Red spectroscopy (FT-IR), X-ray powder diffraction (XRD), Differential scanning calorimetry (DSC) and Scanning electron microscope (SEM).					
37348580	7	57	theme	metal	1143:1147	arg1	ions					1149:1152	other heavy metal ions	1131:1152	other heavy metal ions	1131:1152	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
37348580	7	58	theme	excellent	1059:1067	arg1	efficiency					1080:1089	excellent recyclable efficiency	1059:1089	excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions	1059:1152	Also, CS/24Cl/ECH showed excellent recyclable efficiency up to 5 cycle and potential sorbent for other heavy metal ions.					
36933431	5	0	theme	encapsulation	813:825	arg1	efficiency					827:836	enhanced encapsulation efficiency	804:836	enhanced encapsulation efficiency	804:836	Furthermore, Nar/zein-HA nanoparticles showed favorable physical stability and enhanced encapsulation efficiency.					
36933431	4	1	theme	hydrogen-bonding	694:709	arg1	interactions					711:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	Moreover, the microstructure of Nar/zein-HA nanoparticles was maintained primarily by hydrophobic, electrostatic, and hydrogen-bonding interactions.					
36933431	0	2	theme	hyaluronic	81:90	arg1	acid					92:95	hyaluronic acid	81:95	hyaluronic acid	81:95	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	6	3	theme	Nar	933:935	arg1	digestion					920:928	simulated gastrointestinal digestion	893:928	simulated gastrointestinal digestion of Nar	893:935	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	1	4	theme	food	226:229	arg1	research					231:238	food research	226:238	food research	226:238	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	0	5	theme	efficient	101:109	arg1	delivery					111:118	efficient delivery	101:118	efficient delivery of naringenin	101:132	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	5	6	theme	favorable	771:779	arg1	stability					790:798	favorable physical stability	771:798	favorable physical stability	771:798	Furthermore, Nar/zein-HA nanoparticles showed favorable physical stability and enhanced encapsulation efficiency.					
36933431	7	7	theme	Nar	1031:1033	arg1	efficiency					1017:1026	the delivery efficiency	1004:1026	the delivery efficiency of Nar	1004:1033	Overall, these findings indicate that the delivery efficiency of Nar was improved by formulation of ternary nanoparticles.					
36933431	3	8	theme	0.146 ± 0.032	523:535	arg1	zeta-potentials					541:555	zeta-potentials	541:555	zeta-potentials of -19.0 ± 0.7 mV	541:573	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	8	theme	0.146 ± 0.032	523:535	arg1	indexes					512:518	polydispersity indexes	497:518	polydispersity indexes of 0.146 ± 0.032	497:535	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	8	theme	0.146 ± 0.032	523:535	arg1	sizes					472:476	particle sizes	463:476	particle sizes of 209.2 ± 1.9 nm	463:494	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	5	9	theme	physical	781:788	arg1	stability					790:798	favorable physical stability	771:798	favorable physical stability	771:798	Furthermore, Nar/zein-HA nanoparticles showed favorable physical stability and enhanced encapsulation efficiency.					
36933431	6	10	theme	antioxidant	857:867	arg1	capacity					869:876	antioxidant capacity	857:876	antioxidant capacity	857:876	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	3	11	theme	polydispersity	497:510	arg1	indexes					512:518	polydispersity indexes	497:518	polydispersity indexes of 0.146 ± 0.032	497:535	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	2	12	theme	zein	332:335	arg1	nanoparticles					337:349	zein nanoparticles	332:349	zein nanoparticles using an anti-solvent precipitation method	332:392	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	3	13	with	spherical	448:456	arg1	zeta-potentials					541:555	zeta-potentials	541:555	zeta-potentials of -19.0 ± 0.7 mV	541:573	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	13	with	spherical	448:456	arg1	indexes					512:518	polydispersity indexes	497:518	polydispersity indexes of 0.146 ± 0.032	497:535	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	13	with	spherical	448:456	arg1	sizes					472:476	particle sizes	463:476	particle sizes of 209.2 ± 1.9 nm	463:494	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	4	14	theme	hydrophobic	662:672	arg1	interactions					711:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	Moreover, the microstructure of Nar/zein-HA nanoparticles was maintained primarily by hydrophobic, electrostatic, and hydrogen-bonding interactions.					
36933431	6	15	from	release	882:888	arg1	digestion					920:928	simulated gastrointestinal digestion	893:928	simulated gastrointestinal digestion of Nar	893:935	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	3	16	theme	-19.0 ± 0.7 mV	560:573	arg1	zeta-potentials					541:555	zeta-potentials	541:555	zeta-potentials of -19.0 ± 0.7 mV	541:573	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	16	theme	-19.0 ± 0.7 mV	560:573	arg1	indexes					512:518	polydispersity indexes	497:518	polydispersity indexes of 0.146 ± 0.032	497:535	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	16	theme	-19.0 ± 0.7 mV	560:573	arg1	sizes					472:476	particle sizes	463:476	particle sizes of 209.2 ± 1.9 nm	463:494	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	6	17	dep	capacity	869:876	arg1	the					853:855	the	853:855	the	853:855	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	4	18	theme	electrostatic	675:687	arg1	interactions					711:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	hydrophobic, electrostatic, and hydrogen-bonding interactions	662:722	Moreover, the microstructure of Nar/zein-HA nanoparticles was maintained primarily by hydrophobic, electrostatic, and hydrogen-bonding interactions.					
36933431	7	19	theme	delivery	1008:1015	arg1	efficiency					1017:1026	the delivery efficiency	1004:1026	the delivery efficiency of Nar	1004:1033	Overall, these findings indicate that the delivery efficiency of Nar was improved by formulation of ternary nanoparticles.					
36933431	2	20	theme	anti-solvent	360:371	arg1	method					387:392	an anti-solvent precipitation method	357:392	an anti-solvent precipitation method	357:392	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	2	21	theme	precipitation	373:385	arg1	method					387:392	an anti-solvent precipitation method	357:392	an anti-solvent precipitation method	357:392	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	0	22	theme	naringenin	123:132	arg1	delivery					111:118	efficient delivery	101:118	efficient delivery of naringenin	101:132	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	1	23	theme	animal	183:188	arg1	tissues					190:196	animal tissues	183:196	animal tissues	183:196	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	0	24	theme	composite	42:50	arg1	nanoparticles					52:64	novel composite nanoparticles	36:64	novel composite nanoparticles	36:64	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	5	25	theme	Nar/zein-HA	738:748	arg1	nanoparticles					750:762	Nar/zein-HA nanoparticles	738:762	Nar/zein-HA nanoparticles	738:762	Furthermore, Nar/zein-HA nanoparticles showed favorable physical stability and enhanced encapsulation efficiency.					
36933431	3	26	theme	optimal	399:405	arg1	nanoparticles					419:431	The optimal Nar/zein-HA nanoparticles	395:431	The optimal Nar/zein-HA nanoparticles	395:431	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	26	theme	optimal	399:405	arg1	spherical					448:456	spherical	448:456	spherical	448:456	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	0	27	theme	novel	36:40	arg1	nanoparticles					52:64	novel composite nanoparticles	36:64	novel composite nanoparticles	36:64	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	1	28	located	found	174:178	arg2	acid					146:149	Hyaluronic acid	135:149	Hyaluronic acid (HA)	135:154	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	1	28	located	found	174:178	arg1	tissues					190:196	animal tissues	183:196	animal tissues	183:196	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	1	28	located	found	174:178	arg2	polymer					159:165	a polymer	157:165	a polymer mainly found in animal tissues	157:196	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	4	29	theme	nanoparticles	620:632	arg1	microstructure					590:603	the microstructure	586:603	the microstructure of Nar/zein-HA nanoparticles	586:632	Moreover, the microstructure of Nar/zein-HA nanoparticles was maintained primarily by hydrophobic, electrostatic, and hydrogen-bonding interactions.					
36933431	3	30	theme	Nar/zein-HA	407:417	arg1	nanoparticles					419:431	The optimal Nar/zein-HA nanoparticles	395:431	The optimal Nar/zein-HA nanoparticles	395:431	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	30	theme	Nar/zein-HA	407:417	arg1	spherical					448:456	spherical	448:456	spherical	448:456	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	2	31	theme	naringenin	296:305	arg1	improvement					281:291	delivery improvement	272:291	delivery improvement of naringenin (NAR)	272:311	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	0	32	theme	nanoparticles	52:64	arg1	characterization					16:31	characterization	16:31	characterization	16:31	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	0	32	theme	nanoparticles	52:64	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and characterization of novel composite nanoparticles using zein and hyaluronic acid for efficient delivery of naringenin.					
36933431	6	33	from	capacity	869:876	arg1	digestion					920:928	simulated gastrointestinal digestion	893:928	simulated gastrointestinal digestion of Nar	893:935	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	3	34	theme	particle	463:470	arg1	sizes					472:476	particle sizes	463:476	particle sizes of 209.2 ± 1.9 nm	463:494	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	6	35	theme	gastrointestinal	903:918	arg1	digestion					920:928	simulated gastrointestinal digestion	893:928	simulated gastrointestinal digestion of Nar	893:935	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	1	36	theme	Hyaluronic	135:144	arg1	HA					152:153	HA	152:153	HA	152:153	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	1	36	theme	Hyaluronic	135:144	arg1	acid					146:149	Hyaluronic acid	135:149	Hyaluronic acid (HA)	135:154	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	1	36	theme	Hyaluronic	135:144	arg1	polymer					159:165	a polymer	157:165	a polymer mainly found in animal tissues	157:196	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	6	37	theme	simulated	893:901	arg1	digestion					920:928	simulated gastrointestinal digestion	893:928	simulated gastrointestinal digestion of Nar	893:935	Additionally, the antioxidant capacity and release in simulated gastrointestinal digestion of Nar were significantly improved.					
36933431	7	38	theme	ternary	1066:1072	arg1	nanoparticles					1074:1086	ternary nanoparticles	1066:1086	ternary nanoparticles	1066:1086	Overall, these findings indicate that the delivery efficiency of Nar was improved by formulation of ternary nanoparticles.					
36933431	2	39	theme	delivery	272:279	arg1	improvement					281:291	delivery improvement	272:291	delivery improvement of naringenin (NAR)	272:311	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	2	40	used	used	263:266	arg2	it					256:257	it	256:257	it	256:257	In this study, it was used for delivery improvement of naringenin (NAR) by loading it into zein nanoparticles using an anti-solvent precipitation method.					
36933431	7	41	theme	nanoparticles	1074:1086	arg1	formulation					1051:1061	formulation	1051:1061	formulation of ternary nanoparticles	1051:1086	Overall, these findings indicate that the delivery efficiency of Nar was improved by formulation of ternary nanoparticles.					
36933431	3	42	theme	209.2 ± 1.9 nm	481:494	arg1	zeta-potentials					541:555	zeta-potentials	541:555	zeta-potentials of -19.0 ± 0.7 mV	541:573	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	42	theme	209.2 ± 1.9 nm	481:494	arg1	indexes					512:518	polydispersity indexes	497:518	polydispersity indexes of 0.146 ± 0.032	497:535	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	3	42	theme	209.2 ± 1.9 nm	481:494	arg1	sizes					472:476	particle sizes	463:476	particle sizes of 209.2 ± 1.9 nm	463:494	The optimal Nar/zein-HA nanoparticles were uniformly spherical with particle sizes of 209.2 ± 1.9 nm, polydispersity indexes of 0.146 ± 0.032 and zeta-potentials of -19.0 ± 0.7 mV.					
36933431	1	43	theme	important	208:216	arg1	role					218:221	an important role	205:221	an important role	205:221	Hyaluronic acid (HA), a polymer mainly found in animal tissues, plays an important role in food research.					
36933431	5	44	theme	enhanced	804:811	arg1	efficiency					827:836	enhanced encapsulation efficiency	804:836	enhanced encapsulation efficiency	804:836	Furthermore, Nar/zein-HA nanoparticles showed favorable physical stability and enhanced encapsulation efficiency.					
36933431	4	45	theme	Nar/zein-HA	608:618	arg1	nanoparticles					620:632	Nar/zein-HA nanoparticles	608:632	Nar/zein-HA nanoparticles	608:632	Moreover, the microstructure of Nar/zein-HA nanoparticles was maintained primarily by hydrophobic, electrostatic, and hydrogen-bonding interactions.					
36318285	6	0	theme	polyphenol-based	1261:1276	arg1	hydrogels					1289:1297	polyphenol-based cellulosic hydrogels	1261:1297	polyphenol-based cellulosic hydrogels	1261:1297	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	0	1	with	Hydrogels	57:65	arg1	Activity					86:93	Antibacterial Activity	72:93	Antibacterial Activity	72:93	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	1	2	theme	interest	172:179	arg1	topic					157:161	a topic	155:161	a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues	155:272	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	3	theme	viscoelastic	750:761	arg1	properties					763:772	the mechanical and viscoelastic properties	731:772	the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	731:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	1	4	theme	biological	255:264	arg1	tissues					266:272	biological tissues	255:272	biological tissues	255:272	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	5	theme	polymer	841:847	arg1	matrix					849:854	the polymer matrix	837:854	the polymer matrix	837:854	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	6	6	theme	rational	1242:1249	arg1	design					1251:1256	the rational design	1238:1256	the rational design of polyphenol-based cellulosic hydrogels	1238:1297	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	4	7	with	bonding	824:830	arg1	matrix					849:854	the polymer matrix	837:854	the polymer matrix	837:854	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	1	8	theme	tissues	266:272	arg1	features					243:250	the features	239:250	the features of biological tissues	239:272	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	9	theme	polyphenols	860:870	arg1	promotion					802:810	the promotion	798:810	the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	798:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	10	theme	gallic	551:556	arg1	acid					558:561	green tea-derived gallic acid	533:561	green tea-derived gallic acid	533:561	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	11	link	tea-derived	539:549	arg1	acid					558:561	green tea-derived gallic acid	533:561	green tea-derived gallic acid	533:561	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	4	12	theme	mechanical	735:744	arg1	properties					763:772	the mechanical and viscoelastic properties	731:772	the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	731:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	13	theme	vinyl	517:521	arg1	poly					512:515	poly	512:515	poly(vinyl alcohol)	512:530	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	13	theme	vinyl	517:521	arg1	alcohol					523:529	vinyl alcohol	517:529	vinyl alcohol	517:529	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	4	14	dep	%	706:706	arg1	up					693:694	up	693:694	up	693:694	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	4	15	theme	bonding	824:830	arg1	promotion					802:810	the promotion	798:810	the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	798:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	16	theme	green	533:537	arg1	acid					558:561	green tea-derived gallic acid	533:561	green tea-derived gallic acid	533:561	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	4	17	theme	hydrogen	815:822	arg1	bonding					824:830	hydrogen bonding	815:830	hydrogen bonding with the polymer matrix	815:854	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	2	18	theme	outstanding	278:288	arg1	strategy					290:297	An outstanding strategy	275:297	An outstanding strategy for preparing these materials	275:327	An outstanding strategy for preparing these materials relies on reversible and dynamic cross-links within the hydrogel matrix.					
36318285	1	19	theme	scientific	188:197	arg1	community					199:207	the scientific community	184:207	the scientific community due to their ability to mimic the features of biological tissues	184:272	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	0	20	theme	Supramolecular	18:31	arg1	Hydrogels					57:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels	0:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.	0:94	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	5	21	theme	remolding	1070:1078	arg1	ability					1080:1086	remolding ability	1070:1086	remolding ability	1070:1086	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	1	22	from	topic	157:161	arg1	community					199:207	the scientific community	184:207	the scientific community due to their ability to mimic the features of biological tissues	184:272	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	1	23	theme	ultratough	110:119	arg1	hydrogels					121:129	ultratough hydrogels	110:129	ultratough hydrogels	110:129	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	24	from	addition	644:651	arg1	concentrations					678:691	concentrations	678:691	concentrations up to 1.2 wt %	678:706	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	4	25	theme	@	658:658	arg1	nanofillers					663:673	TA@CNC nanofillers	656:673	TA@CNC nanofillers	656:673	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	0	26	theme	Ascidian-Inspired	0:16	arg1	Hydrogels					57:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels	0:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.	0:94	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	5	27	theme	antibacterial	1138:1150	arg1	properties					1152:1161	potential antibacterial properties	1128:1161	potential antibacterial properties	1128:1161	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	6	28	theme	new	1220:1222	arg1	prospects					1224:1232	new prospects	1220:1232	new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications	1220:1335	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	1	29	theme	hydrogels	121:129	arg1	design					100:105	The design	96:105	The design of ultratough hydrogels	96:129	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	30	theme	TA	656:657	arg1	nanofillers					663:673	TA@CNC nanofillers	656:673	TA@CNC nanofillers	656:673	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	0	31	theme	Nanocomposite	43:55	arg1	Hydrogels					57:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels	0:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.	0:94	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	4	32	theme	due	791:793	arg1	hydrogels					781:789	the hydrogels	777:789	the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	777:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	33	theme	stretchable	465:475	arg1	hydrogels					492:500	stretchable supramolecular hydrogels	465:500	stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	465:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	0	34	theme	Cellulose	33:41	arg1	Hydrogels					57:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels	0:65	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.	0:94	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	5	35	theme	excellent	958:966	arg1	&gt					997:999	&gt	997:999	&gt	997:999	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	35	theme	excellent	958:966	arg1	stretchability					968:981	excellent stretchability	958:981	excellent stretchability	958:981	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	3	36	theme	supramolecular	477:490	arg1	hydrogels					492:500	stretchable supramolecular hydrogels	465:500	stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	465:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	5	37	theme	supramolecular	905:918	arg1	associations					920:931	These supramolecular associations	899:931	These supramolecular associations	899:931	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	38	dep	&gt	997:999	arg1	%					1004:1004	340%	1001:1004	340%	1001:1004	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	38	dep	&gt	997:999	arg1	kPa					1011:1013	540 kPa	1007:1013	540 kPa	1007:1013	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	4	39	theme	hydrogels	781:789	arg1	properties					763:772	the mechanical and viscoelastic properties	731:772	the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions	731:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	6	40	theme	versatile	1170:1178	arg1	materials					1180:1188	These versatile materials	1164:1188	These versatile materials	1164:1188	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	3	41	theme	tannic	574:579	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	41	theme	tannic	574:579	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	5	42	theme	natural	1099:1105	arg1	polyphenols					1107:1117	the natural polyphenols	1095:1117	the natural polyphenols	1095:1117	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	6	43	theme	biomedical	1313:1322	arg1	applications					1324:1335	different biomedical applications	1303:1335	different biomedical applications	1303:1335	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	4	44	dep	bonding	824:830	arg1	interactions					885:896	π-π stacking interactions	872:896	π-π stacking interactions	872:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	5	45	theme	potential	1128:1136	arg1	properties					1152:1161	potential antibacterial properties	1128:1161	potential antibacterial properties	1128:1161	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	4	46	theme	stacking	876:883	arg1	interactions					885:896	π-π stacking interactions	872:896	π-π stacking interactions	872:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	47	theme	acid-coated	581:591	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	47	theme	acid-coated	581:591	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	0	48	theme	Antibacterial	72:84	arg1	Activity					86:93	Antibacterial Activity	72:93	Antibacterial Activity	72:93	Ascidian-Inspired Supramolecular Cellulose Nanocomposite Hydrogels with Antibacterial Activity.					
36318285	4	49	theme	π-π	872:874	arg1	interactions					885:896	π-π stacking interactions	872:896	π-π stacking interactions	872:896	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	50	theme	cellulose	593:601	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	50	theme	cellulose	593:601	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	2	51	theme	dynamic	354:360	arg1	cross-links					362:372	reversible and dynamic cross-links	339:372	reversible and dynamic cross-links within the hydrogel matrix	339:399	An outstanding strategy for preparing these materials relies on reversible and dynamic cross-links within the hydrogel matrix.					
36318285	4	52	with	polyphenols	860:870	arg1	matrix					849:854	the polymer matrix	837:854	the polymer matrix	837:854	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	3	53	theme	rigid	568:572	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	53	theme	rigid	568:572	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	6	54	theme	hydrogels	1289:1297	arg1	design					1251:1256	the rational design	1238:1256	the rational design of polyphenol-based cellulosic hydrogels	1238:1297	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	5	55	theme	low	1017:1019	arg1	transition					1046:1055	low thermoreversible gel-sol transition	1017:1055	low thermoreversible gel-sol transition (60 °C)	1017:1063	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	55	theme	low	1017:1019	arg1	°C					1061:1062	60 °C	1058:1062	60 °C	1058:1062	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	4	56	theme	CNC	659:661	arg1	nanofillers					663:673	TA@CNC nanofillers	656:673	TA@CNC nanofillers	656:673	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	4	57	theme	wt	703:704	arg1	%					706:706	1.2 wt %	699:706	1.2 wt %	699:706	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	5	58	with	hydrogels	943:951	arg1	stretchability					968:981	excellent stretchability	958:981	excellent stretchability	958:981	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	58	with	hydrogels	943:951	arg1	strength					987:994	strength	987:994	strength	987:994	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	58	with	hydrogels	943:951	arg1	transition					1046:1055	low thermoreversible gel-sol transition	1017:1055	low thermoreversible gel-sol transition (60 °C)	1017:1063	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	58	with	hydrogels	943:951	arg1	&gt					997:999	&gt	997:999	&gt	997:999	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	58	with	hydrogels	943:951	arg1	ability					1080:1086	remolding ability	1070:1086	remolding ability	1070:1086	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	58	with	hydrogels	943:951	arg1	°C					1061:1062	60 °C	1058:1062	60 °C	1058:1062	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	3	59	theme	tea-derived	539:549	arg1	acid					558:561	green tea-derived gallic acid	533:561	green tea-derived gallic acid	533:561	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	5	60	theme	thermoreversible	1021:1036	arg1	transition					1046:1055	low thermoreversible gel-sol transition	1017:1055	low thermoreversible gel-sol transition (60 °C)	1017:1063	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	60	theme	thermoreversible	1021:1036	arg1	°C					1061:1062	60 °C	1058:1062	60 °C	1058:1062	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	2	61	theme	reversible	339:348	arg1	cross-links					362:372	reversible and dynamic cross-links	339:372	reversible and dynamic cross-links within the hydrogel matrix	339:399	An outstanding strategy for preparing these materials relies on reversible and dynamic cross-links within the hydrogel matrix.					
36318285	6	62	theme	cellulosic	1278:1287	arg1	hydrogels					1289:1297	polyphenol-based cellulosic hydrogels	1261:1297	polyphenol-based cellulosic hydrogels	1261:1297	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	5	63	theme	gel-sol	1038:1044	arg1	transition					1046:1055	low thermoreversible gel-sol transition	1017:1055	low thermoreversible gel-sol transition (60 °C)	1017:1063	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	5	63	theme	gel-sol	1038:1044	arg1	°C					1061:1062	60 °C	1058:1062	60 °C	1058:1062	These supramolecular associations endow the hydrogels with excellent stretchability and strength (&gt;340%, 540 kPa), low thermoreversible gel-sol transition (60 °C), and remolding ability, while the natural polyphenols provided potential antibacterial properties.					
36318285	3	64	theme	TA	617:618	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	64	theme	TA	617:618	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	1	65	theme	great	166:170	arg1	interest					172:179	great interest	166:179	great interest	166:179	The design of ultratough hydrogels has recently emerged as a topic of great interest in the scientific community due to their ability to mimic the features of biological tissues.					
36318285	4	66	theme	nanofillers	663:673	arg1	addition					644:651	The addition	640:651	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt %	640:706	The addition of TA@CNC nanofillers in concentrations up to 1.2 wt % significantly impacted the mechanical and viscoelastic properties of the hydrogels due to the promotion of hydrogen bonding with the polymer matrix and polyphenols π-π stacking interactions.					
36318285	6	67	theme	different	1303:1311	arg1	applications					1324:1335	different biomedical applications	1303:1335	different biomedical applications	1303:1335	These versatile materials can be anticipated to open up new prospects for the rational design of polyphenol-based cellulosic hydrogels for different biomedical applications.					
36318285	3	68	theme	@	619:619	arg1	nanocrystals					603:614	rigid tannic acid-coated cellulose nanocrystals	568:614	rigid tannic acid-coated cellulose nanocrystals (TA@CNC)	568:623	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	3	68	theme	@	619:619	arg1	CNC					620:622	TA@CNC	617:622	TA@CNC	617:622	In this work, inspired by the composition of ascidians' tunic, stretchable supramolecular hydrogels combining poly(vinyl alcohol), green tea-derived gallic acid, and rigid tannic acid-coated cellulose nanocrystals (TA@CNC) were designed.					
36318285	2	69	theme	hydrogel	385:392	arg1	matrix					394:399	the hydrogel matrix	381:399	the hydrogel matrix	381:399	An outstanding strategy for preparing these materials relies on reversible and dynamic cross-links within the hydrogel matrix.					
35630596	6	0	from	phenolics	1115:1123	arg1	extracts					1148:1155	the flower and bark extracts	1128:1155	extracts	1148:1155	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	3	1	theme	bark	461:464	arg1	composition					436:446	composition	436:446	composition of V. opulus bark	436:464	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	1	theme	bark	461:464	arg1	flower					470:475	flower	470:475	flower	470:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	1	theme	bark	461:464	arg1	compounds					426:434	the phenolic compounds composition of V. opulus bark and flower	413:475	the phenolic compounds composition of V. opulus bark and flower	413:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	4	2	theme	148.87	777:782	arg1	µg/mL					784:788	148.87 µg/mL	777:788	148.87 µg/mL	777:788	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	1	3	theme	treatments	161:170	arg1	One					140:142	One	140:142	One	140:142	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	1	3	theme	treatments	161:170	arg1	treatments					161:170	the effective treatments	147:170	the effective treatments for diabetes	147:183	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	3	4	theme	potato	519:524	arg1	digestion					533:541	in vitro potato starch digestion	510:541	in vitro potato starch digestion	510:541	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	4	5	theme	tree-stage	704:713	arg1	digestion					725:733	tree-stage simulated digestion	704:733	tree-stage simulated digestion	704:733	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	5	6	theme	bark	814:817	arg1	extract					819:825	Phenolic bark extract	805:825	Phenolic bark extract	805:825	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	2	7	from	interest	331:338	arg1	inhibitors					351:360	natural inhibitors	343:360	natural inhibitors from various part of plants	343:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	2	7	from	interest	331:338	arg1	part					375:378	various part	367:378	various part of plants	367:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	3	8	theme	in	510:511	arg1	digestion					533:541	in vitro potato starch digestion	510:541	in vitro potato starch digestion	510:541	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	6	9	theme	prominent	1105:1113	arg1	phenolics					1115:1123	the most prominent phenolics	1096:1123	the most prominent phenolics in the flower and bark extracts	1096:1155	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	9	theme	prominent	1105:1113	arg1	acid					1013:1016	Chlorogenic acid	1001:1016	Chlorogenic acid (27.26% of total phenolics)	1001:1044	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	9	theme	prominent	1105:1113	arg1	-catechin					1053:1061	(+)-catechin	1050:1061	(+)-catechin (30.48% of total phenolics)	1050:1089	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	4	10	attach	released	669:676	arg2	glucose					661:667	glucose	661:667	glucose released from potato starch	661:695	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	4	10	attach	released	669:676	arg1	starch					690:695	potato starch	683:695	potato starch	683:695	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	0	11	theme	Hydrolases	119:128	arg1	Activity					130:137	Carbohydrate Hydrolases Activity	106:137	Carbohydrate Hydrolases Activity	106:137	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	7	12	dep	-catechin	1285:1293	arg1	α-glucosidase					1307:1319	α-glucosidase	1307:1319	α-glucosidase	1307:1319	Procyanidins may be responsible for the strongest V. opulus bark inhibitory activity against α-amylase, while (+)-catechin relative to α-glucosidase.					
35630596	7	12	dep	-catechin	1285:1293	arg1	+					1283:1283	+	1283:1283	+	1283:1283	Procyanidins may be responsible for the strongest V. opulus bark inhibitory activity against α-amylase, while (+)-catechin relative to α-glucosidase.					
35630596	4	13	theme	glucose	661:667	arg1	amount					651:656	the amount	647:656	the amount of glucose released from potato starch	647:695	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	4	13	theme	glucose	661:667	arg1	glucose					661:667	glucose	661:667	glucose released from potato starch	661:695	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	8	14	with	nutraceuticals	1451:1464	arg1	activity					1505:1512	antidiabetic activity	1492:1512	antidiabetic activity	1492:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	7	15	theme	strongest	1212:1220	arg1	activity					1248:1255	the strongest V. opulus bark inhibitory activity	1208:1255	the strongest V. opulus bark inhibitory activity against α-amylase	1208:1273	Procyanidins may be responsible for the strongest V. opulus bark inhibitory activity against α-amylase, while (+)-catechin relative to α-glucosidase.					
35630596	4	16	theme	phenolic	621:628	arg1	extracts					630:637	flower phenolic extracts	614:637	flower phenolic extracts	614:637	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	3	17	dep	in	510:511	arg1	vitro					513:517	vitro	513:517	vitro	513:517	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	0	18	theme	Extracts	63:70	arg1	Effects					20:26	In Vitro Inhibitory Effects	0:26	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.	0:138	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	8	19	theme	examination	1375:1385	arg1	basis					1358:1362	the basis	1354:1362	the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity	1354:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	5	20	dep	%	848:848	arg1	activity					873:880	more potent inhibitory activity	850:880	38.4% more potent inhibitory activity against α-amylase and α-glucosidase	844:916	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	3	21	from	effects	499:505	arg1	α-glucosidase					571:583	α-glucosidase	571:583	α-glucosidase	571:583	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	21	from	effects	499:505	arg1	α-amylase					557:565	α-amylase	557:565	α-amylase	557:565	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	21	from	effects	499:505	arg1	digestion					533:541	in vitro potato starch digestion	510:541	in vitro potato starch digestion	510:541	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	2	22	theme	various	367:373	arg1	part					375:378	various part	367:378	various part of plants	367:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	0	23	theme	Potato	88:93	arg1	Starch					95:100	Potato Starch	88:100	Potato Starch	88:100	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	0	24	theme	In	0:1	arg1	Effects					20:26	In Vitro Inhibitory Effects	0:26	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.	0:138	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	1	25	theme	α-amylase	251:259	arg1	inhibition					237:246	inhibition	237:246	inhibition of α-amylase and α-glucosidase in the digestive tract	237:300	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	5	26	theme	inhibitory	862:871	arg1	activity					873:880	more potent inhibitory activity	850:880	38.4% more potent inhibitory activity against α-amylase and α-glucosidase	844:916	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	8	27	theme	opulus	1412:1417	arg1	compounds					1424:1432	V. opulus bark compounds	1409:1432	V. opulus bark compounds	1409:1432	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	3	28	theme	phenolic	417:424	arg1	composition					436:446	composition	436:446	composition of V. opulus bark	436:464	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	28	theme	phenolic	417:424	arg1	flower					470:475	flower	470:475	flower	470:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	28	theme	phenolic	417:424	arg1	compounds					426:434	the phenolic compounds composition of V. opulus bark and flower	413:475	the phenolic compounds composition of V. opulus bark and flower	413:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	0	29	theme	Inhibitory	9:18	arg1	Effects					20:26	In Vitro Inhibitory Effects	0:26	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.	0:138	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	1	30	theme	α-glucosidase	265:277	arg1	inhibition					237:246	inhibition	237:246	inhibition of α-amylase and α-glucosidase in the digestive tract	237:300	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	8	31	theme	compounds	1424:1432	arg1	suitability					1394:1404	the suitability	1390:1404	the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity	1390:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	3	32	theme	V.	451:452	arg1	bark					461:464	V. opulus bark	451:464	V. opulus bark	451:464	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	0	33	theme	opulus	40:45	arg1	Bark					47:50	Viburnum opulus Bark	31:50	Viburnum opulus Bark	31:50	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	0	34	from	Effects	20:26	arg1	Digestion					75:83	Digestion	75:83	Digestion of Potato Starch and Carbohydrate Hydrolases Activity	75:137	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	5	35	theme	extracts	959:966	arg1	lower					972:976	lower	972:976	lower	972:976	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	5	35	theme	extracts	959:966	arg1	activity					941:948	the activity	937:948	the activity of plant extracts	937:966	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	6	36	theme	phenolics	1035:1043	arg1	%					1024:1024	27.26%	1019:1024	27.26% of total phenolics	1019:1043	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	36	theme	phenolics	1035:1043	arg1	phenolics					1035:1043	total phenolics	1029:1043	total phenolics	1029:1043	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	8	37	theme	nutraceuticals	1451:1464	arg1	components					1437:1446	components	1437:1446	components of nutraceuticals and functional foods with antidiabetic activity	1437:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	4	38	theme	equal	752:756	arg1	value					746:750	IC50 value	741:750	IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively	741:802	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	8	39	theme	functional	1470:1479	arg1	foods					1481:1485	functional foods	1470:1485	functional foods	1470:1485	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	3	40	dep	compounds	426:434	arg1	composition					436:446	composition	436:446	composition of V. opulus bark	436:464	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	40	dep	compounds	426:434	arg1	flower					470:475	flower	470:475	flower	470:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	40	dep	compounds	426:434	arg1	compounds					426:434	the phenolic compounds composition of V. opulus bark and flower	413:475	the phenolic compounds composition of V. opulus bark and flower	413:475	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	2	41	theme	great	325:329	arg1	interest					331:338	a great interest	323:338	a great interest in natural inhibitors from various part of plants	323:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	1	42	theme	glucose	226:232	arg1	absorption					212:221	the absorption	208:221	the absorption of glucose	208:232	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	6	43	theme	bark	1143:1146	arg1	extracts					1148:1155	the flower and bark extracts	1128:1155	extracts	1148:1155	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	3	44	theme	inhibitory	488:497	arg1	effects					499:505	their inhibitory effects	482:505	their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase	482:583	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	6	45	theme	flower	1132:1137	arg1	extracts					1148:1155	the flower and bark extracts	1128:1155	extracts	1148:1155	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	8	46	with	foods	1481:1485	arg1	activity					1505:1512	antidiabetic activity	1492:1512	antidiabetic activity	1492:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	1	47	theme	effective	151:159	arg1	treatments					161:170	the effective treatments	147:170	the effective treatments for diabetes	147:183	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	5	48	theme	Phenolic	805:812	arg1	extract					819:825	Phenolic bark extract	805:825	Phenolic bark extract	805:825	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	6	49	theme	total	1074:1078	arg1	phenolics					1080:1088	total phenolics	1074:1088	total phenolics	1074:1088	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	1	50	from	inhibition	237:246	arg1	tract					296:300	the digestive tract	282:300	the digestive tract	282:300	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	7	51	dep	strongest	1212:1220	arg1	opulus					1225:1230	opulus	1225:1230	opulus	1225:1230	Procyanidins may be responsible for the strongest V. opulus bark inhibitory activity against α-amylase, while (+)-catechin relative to α-glucosidase.					
35630596	7	51	dep	strongest	1212:1220	arg1	inhibitory					1237:1246	inhibitory	1237:1246	inhibitory	1237:1246	Procyanidins may be responsible for the strongest V. opulus bark inhibitory activity against α-amylase, while (+)-catechin relative to α-glucosidase.					
35630596	6	52	dep	-catechin	1053:1061	arg1	+					1051:1051	+	1051:1051	+	1051:1051	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	52	dep	-catechin	1053:1061	arg1	phenolics					1080:1088	total phenolics	1074:1088	total phenolics	1074:1088	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	52	dep	-catechin	1053:1061	arg1	%					1069:1069	30.48%	1064:1069	30.48% of total phenolics	1064:1088	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	0	53	theme	Activity	130:137	arg1	Digestion					75:83	Digestion	75:83	Digestion of Potato Starch and Carbohydrate Hydrolases Activity	75:137	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	8	54	theme	preliminary	1327:1337	arg1	study					1339:1343	This preliminary study	1322:1343	This preliminary study	1322:1343	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	3	55	theme	starch	526:531	arg1	digestion					533:541	in vitro potato starch digestion	510:541	in vitro potato starch digestion	510:541	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	0	56	theme	Carbohydrate	106:117	arg1	Activity					130:137	Carbohydrate Hydrolases Activity	106:137	Carbohydrate Hydrolases Activity	106:137	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	3	57	from	compounds	426:434	arg1	α-glucosidase					571:583	α-glucosidase	571:583	α-glucosidase	571:583	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	57	from	compounds	426:434	arg1	α-amylase					557:565	α-amylase	557:565	α-amylase	557:565	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	3	57	from	compounds	426:434	arg1	digestion					533:541	in vitro potato starch digestion	510:541	in vitro potato starch digestion	510:541	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	6	58	theme	phenolics	1080:1088	arg1	phenolics					1080:1088	total phenolics	1074:1088	total phenolics	1074:1088	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	58	theme	phenolics	1080:1088	arg1	%					1069:1069	30.48%	1064:1069	30.48% of total phenolics	1064:1088	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	0	59	theme	Flower	56:61	arg1	Extracts					63:70	Flower Extracts	56:70	Flower Extracts	56:70	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	8	60	theme	further	1367:1373	arg1	examination					1375:1385	further examination	1367:1385	further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity	1367:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	4	61	theme	flower	614:619	arg1	extracts					630:637	flower phenolic extracts	614:637	flower phenolic extracts	614:637	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	8	62	theme	suitability	1394:1404	arg1	examination					1375:1385	further examination	1367:1385	further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity	1367:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	0	63	theme	Starch	95:100	arg1	Digestion					75:83	Digestion	75:83	Digestion of Potato Starch and Carbohydrate Hydrolases Activity	75:137	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	6	64	theme	Chlorogenic	1001:1011	arg1	acid					1013:1016	Chlorogenic acid	1001:1016	Chlorogenic acid (27.26% of total phenolics)	1001:1044	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	64	theme	Chlorogenic	1001:1011	arg1	phenolics					1115:1123	the most prominent phenolics	1096:1123	the most prominent phenolics in the flower and bark extracts	1096:1155	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	64	theme	Chlorogenic	1001:1011	arg1	-catechin					1053:1061	(+)-catechin	1050:1061	(+)-catechin (30.48% of total phenolics)	1050:1089	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	8	65	theme	V.	1409:1410	arg1	compounds					1424:1432	V. opulus bark compounds	1409:1432	V. opulus bark compounds	1409:1432	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	4	66	theme	simulated	715:723	arg1	digestion					725:733	tree-stage simulated digestion	704:733	tree-stage simulated digestion	704:733	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	5	67	theme	potent	855:860	arg1	activity					873:880	more potent inhibitory activity	850:880	38.4% more potent inhibitory activity against α-amylase and α-glucosidase	844:916	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	8	68	theme	bark	1419:1422	arg1	compounds					1424:1432	V. opulus bark compounds	1409:1432	V. opulus bark compounds	1409:1432	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	2	69	theme	natural	343:349	arg1	inhibitors					351:360	natural inhibitors	343:360	natural inhibitors from various part of plants	343:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	4	70	theme	potato	683:688	arg1	starch					690:695	potato starch	683:695	potato starch	683:695	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	2	71	theme	plants	383:388	arg1	part					375:378	various part	367:378	various part of plants	367:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	0	72	theme	Viburnum	31:38	arg1	Bark					47:50	Viburnum opulus Bark	31:50	Viburnum opulus Bark	31:50	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	3	73	theme	present	398:404	arg1	study					406:410	the present study	394:410	the present study	394:410	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	6	74	dep	acid	1013:1016	arg1	%					1024:1024	27.26%	1019:1024	27.26% of total phenolics	1019:1043	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	6	74	dep	acid	1013:1016	arg1	phenolics					1035:1043	total phenolics	1029:1043	total phenolics	1029:1043	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	0	75	theme	Bark	47:50	arg1	Effects					20:26	In Vitro Inhibitory Effects	0:26	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.	0:138	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	1	76	theme	digestive	286:294	arg1	tract					296:300	the digestive tract	282:300	the digestive tract	282:300	One of the effective treatments for diabetes is to reduce and delay the absorption of glucose by inhibition of α-amylase and α-glucosidase in the digestive tract.					
35630596	5	77	theme	plant	953:957	arg1	extracts					959:966	plant extracts	953:966	plant extracts	953:966	Phenolic bark extract showed 34.9% and 38.4% more potent inhibitory activity against α-amylase and α-glucosidase, respectively, but the activity of plant extracts was lower than that of acarbose.					
35630596	4	78	theme	87.77	761:765	arg1	µg/mL					767:771	87.77 µg/mL	761:771	87.77 µg/mL	761:771	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
35630596	3	79	theme	opulus	454:459	arg1	bark					461:464	V. opulus bark	451:464	V. opulus bark	451:464	In the present study, the phenolic compounds composition of V. opulus bark and flower, and their inhibitory effects on in vitro potato starch digestion as well as on α-amylase and α-glucosidase, have been studied.					
35630596	0	80	dep	In	0:1	arg1	Vitro					3:7	Vitro	3:7	Vitro	3:7	In Vitro Inhibitory Effects of Viburnum opulus Bark and Flower Extracts on Digestion of Potato Starch and Carbohydrate Hydrolases Activity.					
35630596	6	81	theme	total	1029:1033	arg1	phenolics					1035:1043	total phenolics	1029:1043	total phenolics	1029:1043	Chlorogenic acid (27.26% of total phenolics) and (+)-catechin (30.48% of total phenolics) were the most prominent phenolics in the flower and bark extracts, respectively.					
35630596	8	82	theme	foods	1481:1485	arg1	components					1437:1446	components	1437:1446	components of nutraceuticals and functional foods with antidiabetic activity	1437:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	2	83	from	part	375:378	arg1	interest					331:338	a great interest	323:338	a great interest in natural inhibitors from various part of plants	323:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	2	83	from	part	375:378	arg1	inhibitors					351:360	natural inhibitors	343:360	natural inhibitors from various part of plants	343:388	Currently, there is a great interest in natural inhibitors from various part of plants.					
35630596	8	84	theme	antidiabetic	1492:1503	arg1	activity					1505:1512	antidiabetic activity	1492:1512	antidiabetic activity	1492:1512	This preliminary study provides the basis of further examination of the suitability of V. opulus bark compounds as components of nutraceuticals and functional foods with antidiabetic activity.					
35630596	4	85	theme	IC50	741:744	arg1	value					746:750	IC50 value	741:750	IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively	741:802	Bark and flower phenolic extracts reduced the amount of glucose released from potato starch during tree-stage simulated digestion, with IC50 value equal to 87.77 µg/mL and 148.87 µg/mL, respectively.					
36463841	4	0	theme	catalyst	855:862	arg1	stability					842:850	the stability	838:850	the stability of catalyst	838:862	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	5	1	theme	good	1037:1040	arg1	universality					1042:1053	good universality	1037:1053	good universality	1037:1053	Co3O4@BCC composite also exhibited good universality and reusability.					
36463841	0	2	theme	phenacetin	141:150	arg1	degradation					126:136	degradation	126:136	degradation of phenacetin	126:150	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	9	3	theme	quenching	1624:1632	arg1	experiments					1634:1644	quenching experiments	1624:1644	quenching experiments	1624:1644	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	3	4	theme	0.05 g/L	715:722	arg1	1.0 mM					730:735	1.0 mM	730:735	1.0 mM	730:735	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	4	theme	0.05 g/L	715:722	arg1	/PMS					724:727	Co3O4 (0.05 g/L)/PMS	708:727	Co3O4 (0.05 g/L)/PMS (1.0 mM)	708:736	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	9	5	theme	paramagnetic	1554:1565	arg1	EPR					1578:1580	EPR	1578:1580	EPR	1578:1580	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	5	theme	paramagnetic	1554:1565	arg1	resonance					1567:1575	electron paramagnetic resonance	1545:1575	electron paramagnetic resonance (EPR)	1545:1581	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	3	6	theme	/PMS	612:615	arg1	system					582:587	the system	578:587	the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min	578:638	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	9	7	theme	experiments	1634:1644	arg1	results					1534:1540	the results	1530:1540	the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2	1530:1661	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	10	8	theme	environmentally	1798:1812	arg1	friendly					1814:1821	fabricating environmentally friendly	1786:1821	fabricating environmentally friendly	1786:1821	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	7	9	theme	used	1257:1260	arg1	catalyst					1262:1269	the used catalyst	1253:1269	the used catalyst after the third run (calcination at 400 °C for 5 min)	1253:1323	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	7	10	theme	degradation	1173:1183	arg1	rate					1185:1188	The degradation rate	1169:1188	The degradation rate of PNT	1169:1195	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	7	11	theme	98.0	1223:1226	arg1	%					1218:1218	%	1218:1218	%	1218:1218	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	10	12	theme	PMS	1851:1853	arg1	activation					1855:1864	PMS activation	1851:1864	PMS activation	1851:1864	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	3	13	theme	Co3O4	708:712	arg1	1.0 mM					730:735	1.0 mM	730:735	1.0 mM	730:735	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	13	theme	Co3O4	708:712	arg1	/PMS					724:727	Co3O4 (0.05 g/L)/PMS	708:727	Co3O4 (0.05 g/L)/PMS (1.0 mM)	708:736	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	4	14	theme	Co3O4	805:809	arg1	nanoparticles					811:823	dispersed Co3O4 nanoparticles	795:823	a carrier not only dispersed Co3O4 nanoparticles	776:823	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	6	15	theme	CAP	1102:1104	arg1	SIZ					1094:1096	SIZ	1094:1096	SIZ	1094:1096	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	15	theme	CAP	1102:1104	arg1	BPA					1089:1091	BPA	1089:1091	BPA	1089:1091	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	15	theme	CAP	1102:1104	arg1	%					1084:1084	More than 90%	1072:1084	More than 90% of BPA, SIZ and CAP	1072:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	15	theme	CAP	1102:1104	arg1	CAP					1102:1104	CAP	1102:1104	CAP	1102:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	9	16	theme	possible	1453:1460	arg1	pathways					1462:1469	the possible pathways	1449:1469	the possible pathways of PNT degradation	1449:1488	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	10	17	theme	organic	1877:1883	arg1	pollutants					1885:1894	organic pollutants	1877:1894	organic pollutants	1877:1894	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	9	18	theme	HPLC-TOF-MS2	1650:1661	arg1	results					1534:1540	the results	1530:1540	the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2	1530:1661	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	8	19	theme	PNT	1383:1385	arg1	degradation					1387:1397	PNT degradation	1383:1397	PNT degradation	1383:1397	SO4•-, •OH and 1O2 were identified to be responsible for PNT degradation.					
36463841	2	20	theme	catalytic	482:490	arg1	performance					492:502	catalytic performance	482:502	catalytic performance	482:502	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	6	21	from	pH	1163:1164	arg1	15 min					1153:1158	15 min	1153:1158	15 min at pH 7	1153:1166	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	9	22	theme	activation	1417:1426	arg1	mechanism					1428:1436	the activation mechanism	1413:1436	the activation mechanism of PMS	1413:1443	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	10	23	theme	efficient	1827:1835	arg1	catalysts					1837:1845	efficient catalysts	1827:1845	efficient catalysts for PMS activation	1827:1864	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	4	24	dep	carrier	778:784	arg1	only					790:793	only	790:793	only	790:793	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	6	25	theme	SIZ	1094:1096	arg1	SIZ					1094:1096	SIZ	1094:1096	SIZ	1094:1096	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	25	theme	SIZ	1094:1096	arg1	BPA					1089:1091	BPA	1089:1091	BPA	1089:1091	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	25	theme	SIZ	1094:1096	arg1	%					1084:1084	More than 90%	1072:1084	More than 90% of BPA, SIZ and CAP	1072:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	25	theme	SIZ	1094:1096	arg1	CAP					1102:1104	CAP	1102:1104	CAP	1102:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	0	26	attach	derived	26:32	arg1	BCC					55:57	Co3O4@BCC	49:57	Co3O4@BCC	49:57	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	0	26	attach	derived	26:32	arg1	chitosan					39:46	chitosan	39:46	chitosan (Co3O4@BCC)	39:58	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	0	26	attach	derived	26:32	arg2	biochar					18:24	biochar	18:24	biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin	18:150	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	9	27	theme	resonance	1567:1575	arg1	results					1534:1540	the results	1530:1540	the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2	1530:1661	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	4	28	theme	dispersed	795:803	arg1	nanoparticles					811:823	dispersed Co3O4 nanoparticles	795:823	a carrier not only dispersed Co3O4 nanoparticles	776:823	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	7	29	from	400 °C	1307:1312	arg1	calcination					1292:1302	calcination	1292:1302	calcination	1292:1302	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	2	30	theme	experimental	396:407	arg1	designs					409:415	experimental designs	396:415	experimental designs	396:415	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	9	31	theme	PNT	1474:1476	arg1	degradation					1478:1488	PNT degradation	1474:1488	PNT degradation	1474:1488	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	4	32	theme	abundant	883:890	arg1	groups					906:911	abundant electron-rich groups	883:911	abundant electron-rich groups	883:911	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	10	33	theme	recycled	1717:1724	arg1	application					1688:1698	the application	1684:1698	the application of chitosan	1684:1710	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	10	33	theme	recycled	1717:1724	arg1	material					1726:1733	a recycled material	1715:1733	a recycled material	1715:1733	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	6	34	theme	BPA	1089:1091	arg1	SIZ					1094:1096	SIZ	1094:1096	SIZ	1094:1096	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	34	theme	BPA	1089:1091	arg1	BPA					1089:1091	BPA	1089:1091	BPA	1089:1091	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	34	theme	BPA	1089:1091	arg1	%					1084:1084	More than 90%	1072:1084	More than 90% of BPA, SIZ and CAP	1072:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	6	34	theme	BPA	1089:1091	arg1	CAP					1102:1104	CAP	1102:1104	CAP	1102:1104	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	7	35	theme	90	1216:1217	arg1	%					1218:1218	%	1218:1218	%	1218:1218	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	4	36	theme	reactive	971:978	arg1	ROS					996:998	ROS	996:998	ROS	996:998	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	4	36	theme	reactive	971:978	arg1	species					987:993	reactive oxygen species	971:993	reactive oxygen species (ROS)	971:999	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	1	37	theme	cobalt-based	237:248	arg1	catalyst					250:257	cobalt-based catalyst	237:257	cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT)	237:351	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	1	37	theme	cobalt-based	237:248	arg1	BCC					266:268	Co3O4@BCC	260:268	Co3O4@BCC	260:268	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	9	38	theme	PMS	1441:1443	arg1	mechanism					1428:1436	the activation mechanism	1413:1436	the activation mechanism of PMS	1413:1443	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	38	theme	PMS	1441:1443	arg1	pathways					1462:1469	the possible pathways	1449:1469	the possible pathways of PNT degradation	1449:1488	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	7	39	dep	run	1287:1289	arg1	calcination					1292:1302	calcination	1292:1302	calcination	1292:1302	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	2	40	theme	Various	354:360	arg1	technologies					379:390	Various characterization technologies	354:390	Various characterization technologies	354:390	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	2	41	theme	characterization	362:377	arg1	technologies					379:390	Various characterization technologies	354:390	Various characterization technologies	354:390	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	3	42	theme	rate	648:651	arg1	higher					674:679	higher	674:679	higher	674:679	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	42	theme	rate	648:651	arg1	constant					653:660	the rate constant	644:660	the rate constant	644:660	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	2	43	theme	BCC	513:515	arg1	properties					467:476	the physicochemical properties	447:476	the physicochemical properties	447:476	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	2	43	theme	BCC	513:515	arg1	performance					492:502	catalytic performance	482:502	catalytic performance	482:502	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	3	44	theme	Co3O4	592:596	arg1	1.0 mM					618:623	1.0 mM	618:623	1.0 mM	618:623	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	44	theme	Co3O4	592:596	arg1	/PMS					612:615	Co3O4@BCC (0.05 g/L)/PMS	592:615	Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min	592:638	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	4	45	theme	species	987:993	arg1	activation					931:940	the activation	927:940	the activation of PMS	927:947	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	4	45	theme	species	987:993	arg1	production					957:966	the production	953:966	the production of reactive oxygen species (ROS)	953:999	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	10	46	theme	chitosan	1703:1710	arg1	application					1688:1698	the application	1684:1698	the application of chitosan	1684:1710	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	10	46	theme	chitosan	1703:1710	arg1	material					1726:1733	a recycled material	1715:1733	a recycled material	1715:1733	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	2	47	theme	@	512:512	arg1	BCC					513:515	Co3O4@BCC	507:515	Co3O4@BCC	507:515	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	3	48	theme	@	597:597	arg1	1.0 mM					618:623	1.0 mM	618:623	1.0 mM	618:623	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	48	theme	@	597:597	arg1	/PMS					612:615	Co3O4@BCC (0.05 g/L)/PMS	592:615	Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min	592:638	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	4	49	theme	oxygen	980:985	arg1	ROS					996:998	ROS	996:998	ROS	996:998	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	4	49	theme	oxygen	980:985	arg1	species					987:993	reactive oxygen species	971:993	reactive oxygen species (ROS)	971:999	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	1	50	theme	Co3O4	260:264	arg1	catalyst					250:257	cobalt-based catalyst	237:257	cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT)	237:351	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	1	50	theme	Co3O4	260:264	arg1	BCC					266:268	Co3O4@BCC	260:268	Co3O4@BCC	260:268	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	2	51	theme	Co3O4	507:511	arg1	BCC					513:515	Co3O4@BCC	507:515	Co3O4@BCC	507:515	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	7	52	theme	PNT	1193:1195	arg1	rate					1185:1188	The degradation rate	1169:1188	The degradation rate of PNT	1169:1195	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	10	53	theme	fabricating	1786:1796	arg1	friendly					1814:1821	fabricating environmentally friendly	1786:1821	fabricating environmentally friendly	1786:1821	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	1	54	theme	bio-friendly	168:179	arg1	precursor					202:210	a bio-friendly and abundant biochar precursor	166:210	a bio-friendly and abundant biochar precursor	166:210	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	9	55	theme	X-ray	1584:1588	arg1	XPS					1618:1620	XPS	1618:1620	XPS	1618:1620	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	55	theme	X-ray	1584:1588	arg1	spectroscopy					1604:1615	X-ray photoelectron spectroscopy	1584:1615	X-ray photoelectron spectroscopy (XPS)	1584:1621	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	1	56	theme	@	265:265	arg1	catalyst					250:257	cobalt-based catalyst	237:257	cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT)	237:351	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	1	56	theme	@	265:265	arg1	BCC					266:268	Co3O4@BCC	260:268	Co3O4@BCC	260:268	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	6	57	theme	activated	1132:1140	arg1	PMS					1142:1144	Co3O4@BCC activated PMS	1122:1144	Co3O4@BCC activated PMS	1122:1144	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	2	58	theme	physicochemical	451:465	arg1	properties					467:476	the physicochemical properties	447:476	the physicochemical properties	447:476	Various characterization technologies and experimental designs were performed to investigate the physicochemical properties and catalytic performance of Co3O4@BCC.					
36463841	3	59	theme	phenacetin	541:550	arg1	10 mg/L					553:559	10 mg/L	553:559	10 mg/L	553:559	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	59	theme	phenacetin	541:550	arg1	phenacetin					541:550	phenacetin	541:550	phenacetin (10 mg/L)	541:560	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	59	theme	phenacetin	541:550	arg1	%					536:536	Approximately 99.0%	518:536	Approximately 99.0% of phenacetin (10 mg/L)	518:560	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	9	60	theme	degradation	1478:1488	arg1	mechanism					1428:1436	the activation mechanism	1413:1436	the activation mechanism of PMS	1413:1443	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	60	theme	degradation	1478:1488	arg1	pathways					1462:1469	the possible pathways	1449:1469	the possible pathways of PNT degradation	1449:1488	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	7	61	dep	%	1218:1218	arg1	to					1220:1221	to	1220:1221	to	1220:1221	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	9	62	theme	photoelectron	1590:1602	arg1	XPS					1618:1620	XPS	1618:1620	XPS	1618:1620	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	62	theme	photoelectron	1590:1602	arg1	spectroscopy					1604:1615	X-ray photoelectron spectroscopy	1584:1615	X-ray photoelectron spectroscopy (XPS)	1584:1621	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	5	63	theme	BCC	1008:1010	arg1	composite					1012:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite also exhibited good universality and reusability.					
36463841	6	64	theme	BCC	1128:1130	arg1	PMS					1142:1144	Co3O4@BCC activated PMS	1122:1144	Co3O4@BCC activated PMS	1122:1144	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	3	65	theme	0.05 g/L	603:610	arg1	1.0 mM					618:623	1.0 mM	618:623	1.0 mM	618:623	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	65	theme	0.05 g/L	603:610	arg1	/PMS					612:615	Co3O4@BCC (0.05 g/L)/PMS	592:615	Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min	592:638	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	5	66	theme	Co3O4	1002:1006	arg1	composite					1012:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite also exhibited good universality and reusability.					
36463841	9	67	theme	spectroscopy	1604:1615	arg1	results					1534:1540	the results	1530:1540	the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2	1530:1661	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	6	68	theme	@	1127:1127	arg1	BCC					1128:1130	Co3O4@BCC	1122:1130	Co3O4@BCC activated PMS	1122:1144	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	4	69	theme	PMS	945:947	arg1	activation					931:940	the activation	927:940	the activation of PMS	927:947	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	4	69	theme	PMS	945:947	arg1	production					957:966	the production	953:966	the production of reactive oxygen species (ROS)	953:999	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	6	70	theme	Co3O4	1122:1126	arg1	BCC					1128:1130	Co3O4@BCC	1122:1130	Co3O4@BCC activated PMS	1122:1144	More than 90% of BPA, SIZ and CAP was degraded by Co3O4@BCC activated PMS within 15 min at pH 7.					
36463841	3	71	theme	BCC	598:600	arg1	1.0 mM					618:623	1.0 mM	618:623	1.0 mM	618:623	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	3	71	theme	BCC	598:600	arg1	/PMS					612:615	Co3O4@BCC (0.05 g/L)/PMS	592:615	Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min	592:638	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	9	72	theme	electron	1545:1552	arg1	EPR					1578:1580	EPR	1578:1580	EPR	1578:1580	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	9	72	theme	electron	1545:1552	arg1	resonance					1567:1575	electron paramagnetic resonance	1545:1575	electron paramagnetic resonance (EPR)	1545:1581	Furthermore, the activation mechanism of PMS and the possible pathways of PNT degradation were reasonably speculated according to the results of electron paramagnetic resonance (EPR), X-ray photoelectron spectroscopy (XPS), quenching experiments and HPLC-TOF-MS2.					
36463841	3	73	theme	/PMS	724:727	arg1	system					698:703	the system	694:703	the system of Co3O4 (0.05 g/L)/PMS (1.0 mM)	694:736	Approximately 99.0% of phenacetin (10 mg/L) was degraded in the system of Co3O4@BCC (0.05 g/L)/PMS (1.0 mM) within 15 min and the rate constant was 6 times higher than that in the system of Co3O4 (0.05 g/L)/PMS (1.0 mM).					
36463841	1	74	theme	abundant	185:192	arg1	precursor					202:210	a bio-friendly and abundant biochar precursor	166:210	a bio-friendly and abundant biochar precursor	166:210	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	0	75	theme	@	54:54	arg1	BCC					55:57	Co3O4@BCC	49:57	Co3O4@BCC	49:57	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	0	75	theme	@	54:54	arg1	chitosan					39:46	chitosan	39:46	chitosan (Co3O4@BCC)	39:58	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	7	76	theme	third	1281:1285	arg1	run					1287:1289	the third run	1277:1289	the third run (calcination at 400 °C for 5 min)	1277:1323	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	1	77	theme	biochar	194:200	arg1	precursor					202:210	a bio-friendly and abundant biochar precursor	166:210	a bio-friendly and abundant biochar precursor	166:210	Chitosan, as a bio-friendly and abundant biochar precursor, was employed to prepare cobalt-based catalyst (Co3O4@BCC) by calcination for activating peroxymonosulfate (PMS) to degrade phenacetin (PNT).					
36463841	0	78	theme	Co3O4	49:53	arg1	BCC					55:57	Co3O4@BCC	49:57	Co3O4@BCC	49:57	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	0	78	theme	Co3O4	49:53	arg1	chitosan					39:46	chitosan	39:46	chitosan (Co3O4@BCC)	39:58	Co3O4 anchored on biochar derived from chitosan (Co3O4@BCC) as a catalyst to efficiently activate peroxymonosulfate (PMS) for degradation of phenacetin.					
36463841	7	79	theme	catalyst	1262:1269	arg1	regeneration					1237:1248	the regeneration	1233:1248	the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min)	1233:1323	The degradation rate of PNT was recovered from 90% to 98.0% via the regeneration of the used catalyst after the third run (calcination at 400 °C for 5 min).					
36463841	10	80	theme	feasible	1750:1757	arg1	strategy					1759:1766	a feasible strategy	1748:1766	a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants	1748:1894	This study explored the application of chitosan as a recycled material and provides a feasible strategy for designing and fabricating environmentally friendly and efficient catalysts for PMS activation to degrade organic pollutants.					
36463841	4	81	theme	electron-rich	892:904	arg1	groups					906:911	abundant electron-rich groups	883:911	abundant electron-rich groups	883:911	The results demonstrated that BCC as a carrier not only dispersed Co3O4 nanoparticles and improved the stability of catalyst, but also provided abundant electron-rich groups to facilitate the activation of PMS and the production of reactive oxygen species (ROS).					
36463841	5	82	theme	@	1007:1007	arg1	composite					1012:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite	1002:1020	Co3O4@BCC composite also exhibited good universality and reusability.					
36736518	3	0	from	effect	378:383	arg1	beads					582:586	beads	582:586	beads	582:586	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	0	from	effect	378:383	arg1	emulsions					568:576	the emulsions	564:576	the emulsions	564:576	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	4	1	theme	MEO	669:671	arg1	composition					682:692	MEO chemical composition	669:692	MEO chemical composition	669:692	MEO chemical composition and antimicrobial activity were assessed.					
36736518	3	2	theme	isolate	490:496	arg1	WPI					499:501	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	2	theme	isolate	490:496	arg1	concentration					447:459	emulsifier concentration	436:459	emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI))	436:503	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	0	3	theme	sodium	70:75	arg1	alginate					77:84	sodium alginate	70:84	sodium alginate	70:84	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	3	4	theme	composite	651:659	arg1	design					661:666	a rotatable central composite design	631:666	a rotatable central composite design	631:666	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	0	5	theme	whey	90:93	arg1	protein					95:101	whey protein	90:101	whey protein	90:101	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	3	6	theme	concentration	524:536	arg1	effect					378:383	The effect	374:383	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties	374:597	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	6	7	theme	beads	979:983	arg1	structure					962:970	the porous structure	951:970	the porous structure of the beads	951:983	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	0	8	dep	alginate	77:84	arg1	isolate					103:109	isolate	103:109	isolate	103:109	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	3	9	theme	cationic	510:517	arg1	concentration					524:536	cationic bath concentration	510:536	cationic bath concentration (0.05-0.3 mol/L CaCl2)	510:559	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	9	theme	cationic	510:517	arg1	CaCl2					554:558	0.05-0.3 mol/L CaCl2	539:558	0.05-0.3 mol/L CaCl2	539:558	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	2	10	dep	Origanum	333:340	arg1	L.					351:352	Origanum majorana L.	333:352	Origanum majorana L.	333:352	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	8	11	theme	appropriate	1290:1300	arg1	concentration					1169:1181	The intermediate concentration	1152:1181	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L)	1152:1262	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	11	theme	appropriate	1290:1300	arg1	conditions					1302:1311	the most appropriate conditions	1281:1311	the most appropriate conditions	1281:1311	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	3	12	theme	concentration	447:459	arg1	effect					378:383	The effect	374:383	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties	374:597	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	1	13	used	used	151:154	arg2	techniques					126:135	Encapsulation techniques	112:135	Encapsulation techniques	112:135	Encapsulation techniques are generally used to preserve the volatile compounds of essential oils.					
36736518	3	14	theme	alginate	395:402	arg1	0.5-2 g/100 mL					419:432	0.5-2 g/100 mL	419:432	0.5-2 g/100 mL	419:432	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	14	theme	alginate	395:402	arg1	concentration					404:416	sodium alginate concentration	388:416	sodium alginate concentration (0.5-2 g/100 mL)	388:433	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	8	15	theme	CaCl2	1244:1248	arg1	conditions					1302:1311	the most appropriate conditions	1281:1311	the most appropriate conditions	1281:1311	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	15	theme	CaCl2	1244:1248	arg1	concentration					1169:1181	The intermediate concentration	1152:1181	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L)	1152:1262	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	3	16	dep	emulsions	568:576	arg1	properties					588:597	properties	588:597	properties	588:597	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	2	17	theme	variables	264:272	arg1	influence					243:251	the influence	239:251	the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation	239:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	1	18	theme	volatile	172:179	arg1	compounds					181:189	the volatile compounds	168:189	the volatile compounds of essential oils	168:207	Encapsulation techniques are generally used to preserve the volatile compounds of essential oils.					
36736518	8	19	theme	intermediate	1156:1167	arg1	conditions					1302:1311	the most appropriate conditions	1281:1311	the most appropriate conditions	1281:1311	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	19	theme	intermediate	1156:1167	arg1	concentration					1169:1181	The intermediate concentration	1152:1181	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L)	1152:1262	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	7	20	theme	emulsion	1091:1098	arg1	viscosity					1100:1108	emulsion viscosity	1091:1108	emulsion viscosity	1091:1108	High alginate concentrations also increased emulsion viscosity, affecting positively beads' circularity.					
36736518	2	21	theme	oil	322:324	arg1	microencapsulation					281:298	the microencapsulation	277:298	the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation	277:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	22	theme	ionic	358:362	arg1	gelation					364:371	ionic gelation	358:371	ionic gelation	358:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	6	23	theme	High	899:902	arg1	concentrations					904:917	High concentrations	899:917	High concentrations of alginate and WPI	899:937	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	2	24	theme	essential	312:320	arg1	MEO					327:329	MEO	327:329	MEO	327:329	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	24	theme	essential	312:320	arg1	Origanum					333:340	Origanum	333:340	Origanum	333:340	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	24	theme	essential	312:320	arg1	oil					322:324	marjoram essential oil	303:324	marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation	303:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	25	from	influence	243:251	arg1	microencapsulation					281:298	the microencapsulation	277:298	the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation	277:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	3	26	theme	concentration	404:416	arg1	effect					378:383	The effect	374:383	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties	374:597	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	0	27	theme	essential	31:39	arg1	oil					41:43	marjoram essential oil	22:43	marjoram essential oil	22:43	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	8	28	theme	alginate	1193:1200	arg1	conditions					1302:1311	the most appropriate conditions	1281:1311	the most appropriate conditions	1281:1311	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	28	theme	alginate	1193:1200	arg1	concentration					1169:1181	The intermediate concentration	1152:1181	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L)	1152:1262	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	2	29	theme	marjoram	303:310	arg1	MEO					327:329	MEO	327:329	MEO	327:329	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	29	theme	marjoram	303:310	arg1	Origanum					333:340	Origanum	333:340	Origanum	333:340	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	2	29	theme	marjoram	303:310	arg1	oil					322:324	marjoram essential oil	303:324	marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation	303:371	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	1	30	theme	essential	194:202	arg1	oils					204:207	essential oils	194:207	essential oils	194:207	Encapsulation techniques are generally used to preserve the volatile compounds of essential oils.					
36736518	0	31	theme	marjoram	22:29	arg1	oil					41:43	marjoram essential oil	22:43	marjoram essential oil	22:43	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	6	32	theme	porous	955:960	arg1	structure					962:970	the porous structure	951:970	the porous structure of the beads	951:983	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	8	33	theme	high	1364:1367	arg1	efficiency					1383:1392	high encapsulation efficiency	1364:1392	high encapsulation efficiency	1364:1392	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	0	34	dep	additive	55:62	arg1	using					64:68	using	64:68	using sodium alginate and whey protein isolate	64:109	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	1	35	theme	oils	204:207	arg1	compounds					181:189	the volatile compounds	168:189	the volatile compounds of essential oils	168:207	Encapsulation techniques are generally used to preserve the volatile compounds of essential oils.					
36736518	5	36	theme	droplet	769:775	arg1	size					777:780	droplet size	769:780	droplet size	769:780	Emulsions were characterized for droplet size and viscosity, while the particles were analyzed for encapsulation efficiency, size and circularity, and morphology.					
36736518	3	37	theme	protein	482:488	arg1	WPI					499:501	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	37	theme	protein	482:488	arg1	concentration					447:459	emulsifier concentration	436:459	emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI))	436:503	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	7	38	theme	alginate	1052:1059	arg1	concentrations					1061:1074	High alginate concentrations	1047:1074	High alginate concentrations	1047:1074	High alginate concentrations also increased emulsion viscosity, affecting positively beads' circularity.					
36736518	0	39	theme	oil	41:43	arg1	Microencapsulation					0:17	Microencapsulation	0:17	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.	0:110	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	3	40	theme	sodium	388:393	arg1	0.5-2 g/100 mL					419:432	0.5-2 g/100 mL	419:432	0.5-2 g/100 mL	419:432	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	40	theme	sodium	388:393	arg1	concentration					404:416	sodium alginate concentration	388:416	sodium alginate concentration (0.5-2 g/100 mL)	388:433	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	8	41	theme	WPI	1219:1221	arg1	conditions					1302:1311	the most appropriate conditions	1281:1311	the most appropriate conditions	1281:1311	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	41	theme	WPI	1219:1221	arg1	concentration					1169:1181	The intermediate concentration	1152:1181	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L)	1152:1262	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	5	42	theme	encapsulation	835:847	arg1	efficiency					849:858	encapsulation efficiency	835:858	encapsulation efficiency	835:858	Emulsions were characterized for droplet size and viscosity, while the particles were analyzed for encapsulation efficiency, size and circularity, and morphology.					
36736518	6	43	theme	WPI	935:937	arg1	concentrations					904:917	High concentrations	899:917	High concentrations of alginate and WPI	899:937	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	8	44	theme	encapsulation	1369:1381	arg1	efficiency					1383:1392	high encapsulation efficiency	1364:1392	high encapsulation efficiency	1364:1392	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	3	45	theme	whey	477:480	arg1	WPI					499:501	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	45	theme	whey	477:480	arg1	concentration					447:459	emulsifier concentration	436:459	emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI))	436:503	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	7	46	theme	High	1047:1050	arg1	concentrations					1061:1074	High alginate concentrations	1047:1074	High alginate concentrations	1047:1074	High alginate concentrations also increased emulsion viscosity, affecting positively beads' circularity.					
36736518	3	47	theme	rotatable	633:641	arg1	design					661:666	a rotatable central composite design	631:666	a rotatable central composite design	631:666	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	8	48	with	beads	1324:1328	arg1	efficiency					1383:1392	high encapsulation efficiency	1364:1392	high encapsulation efficiency	1364:1392	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	48	with	beads	1324:1328	arg1	circularity					1348:1358	satisfactory circularity	1335:1358	satisfactory circularity	1335:1358	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	1	49	theme	Encapsulation	112:124	arg1	techniques					126:135	Encapsulation techniques	112:135	Encapsulation techniques	112:135	Encapsulation techniques are generally used to preserve the volatile compounds of essential oils.					
36736518	6	50	theme	alginate	922:929	arg1	concentrations					904:917	High concentrations	899:917	High concentrations of alginate and WPI	899:937	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	3	51	theme	central	643:649	arg1	design					661:666	a rotatable central composite design	631:666	a rotatable central composite design	631:666	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	2	52	theme	process	256:262	arg1	variables					264:272	process variables	256:272	process variables	256:272	This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation.					
36736518	4	53	theme	antimicrobial	698:710	arg1	activity					712:719	antimicrobial activity	698:719	antimicrobial activity	698:719	MEO chemical composition and antimicrobial activity were assessed.					
36736518	3	54	theme	bath	519:522	arg1	concentration					524:536	cationic bath concentration	510:536	cationic bath concentration (0.05-0.3 mol/L CaCl2)	510:559	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	54	theme	bath	519:522	arg1	CaCl2					554:558	0.05-0.3 mol/L CaCl2	539:558	0.05-0.3 mol/L CaCl2	539:558	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	8	55	theme	sodium	1186:1191	arg1	1.25 g/100 mL					1203:1215	1.25 g/100 mL	1203:1215	1.25 g/100 mL	1203:1215	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	8	55	theme	sodium	1186:1191	arg1	alginate					1193:1200	sodium alginate	1186:1200	sodium alginate (1.25 g/100 mL)	1186:1216	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	3	56	theme	0.5-2 g/100 mL	462:475	arg1	WPI					499:501	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	56	theme	0.5-2 g/100 mL	462:475	arg1	concentration					447:459	emulsifier concentration	436:459	emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI))	436:503	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	8	57	theme	satisfactory	1335:1346	arg1	circularity					1348:1358	satisfactory circularity	1335:1358	satisfactory circularity	1335:1358	The intermediate concentration of sodium alginate (1.25 g/100 mL), WPI (1.25 g/100 mL), and CaCl2 (0.175 mol/L) were selected as the most appropriate conditions to produce beads with satisfactory circularity and high encapsulation efficiency.					
36736518	6	58	theme	encapsulation	1021:1033	arg1	efficiency					1035:1044	encapsulation efficiency	1021:1044	encapsulation efficiency	1021:1044	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	3	59	theme	emulsifier	436:445	arg1	WPI					499:501	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	0.5-2 g/100 mL whey protein isolate (WPI)	462:502	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	59	theme	emulsifier	436:445	arg1	concentration					447:459	emulsifier concentration	436:459	emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI))	436:503	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	6	60	theme	mean	1003:1006	arg1	diameter					1008:1015	droplet mean diameter	995:1015	droplet mean diameter	995:1015	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	0	61	theme	additive	55:62	arg1	food					50:53	a food	48:53	a food additive using sodium alginate and whey protein isolate	48:109	Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate.					
36736518	6	62	theme	droplet	995:1001	arg1	diameter					1008:1015	droplet mean diameter	995:1015	droplet mean diameter	995:1015	High concentrations of alginate and WPI intensified the porous structure of the beads, reducing droplet mean diameter and encapsulation efficiency.					
36736518	3	63	theme	0.05-0.3 mol/L	539:552	arg1	concentration					524:536	cationic bath concentration	510:536	cationic bath concentration (0.05-0.3 mol/L CaCl2)	510:559	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	3	63	theme	0.05-0.3 mol/L	539:552	arg1	CaCl2					554:558	0.05-0.3 mol/L CaCl2	539:558	0.05-0.3 mol/L CaCl2	539:558	The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design.					
36736518	4	64	theme	chemical	673:680	arg1	composition					682:692	MEO chemical composition	669:692	MEO chemical composition	669:692	MEO chemical composition and antimicrobial activity were assessed.					
37031963	8	0	theme	lipoteichoic	1168:1179	arg1	acid					1181:1184	lipoteichoic acid	1168:1184	lipoteichoic acid	1168:1184	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
37031963	7	1	theme	functional	1049:1058	arg1	substances					1060:1069	functional substances	1049:1069	functional substances	1049:1069	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	0	2	theme	TK1501	24:29	arg1	soybeans					41:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	1	3	theme	intestinal	188:197	arg1	floras					199:204	intestinal floras	188:204	intestinal floras	188:204	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	7	4	used	used	1011:1014	arg2	carbohydrates					992:1004	soy carbohydrates	988:1004	soy carbohydrates	988:1004	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	1	5	theme	preservation	261:272	arg1	condition					274:282	the preservation condition	257:282	the preservation condition	257:282	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	0	6	theme	cell	124:127	arg1	function					129:136	intestinal cell function	113:136	intestinal cell function	113:136	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	11	7	theme	storage	1581:1587	arg1	condition					1589:1597	storage condition	1581:1597	storage condition	1581:1597	The fermented food may have a long shelf life and lax storage condition.					
37031963	10	8	theme	fermented	1400:1408	arg1	colitis					1430:1436	TK1501 fermented soybean alleviating colitis	1393:1436	TK1501 fermented soybean alleviating colitis	1393:1436	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	0	9	theme	intestinal	113:122	arg1	function					129:136	intestinal cell function	113:136	intestinal cell function	113:136	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	6	10	theme	dead	898:901	arg1	bacteria					903:910	live or dead bacteria	890:910	bacterial metabolites but not live or dead bacteria	860:910	However, the efficacy was associated with bacterial metabolites but not live or dead bacteria.					
37031963	10	11	theme	lipoteichoic	1490:1501	arg1	metabolites					1454:1464	metabolites	1454:1464	metabolites of TK1501	1454:1474	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	10	11	theme	lipoteichoic	1490:1501	arg1	acid					1503:1506	lipoteichoic acid	1490:1506	lipoteichoic acid	1490:1506	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	4	12	used	used	708:711	arg2	soybeans					672:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	4	12	used	used	708:711	arg2	metabolites					691:701	their metabolites	685:701	their metabolites	685:701	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	8	13	theme	colonic	1198:1204	arg1	macrophage					1206:1215	the colonic macrophage	1194:1215	the colonic macrophage	1194:1215	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
37031963	9	14	theme	macrophages	1357:1367	arg1	phagocytosis					1341:1352	the phagocytosis	1337:1352	the phagocytosis of macrophages	1337:1367	A cell experiment displayed that lipoteichoic acid could enhance the phagocytosis of macrophages.					
37031963	3	15	theme	fermented	516:524	arg1	food					526:529	fermented food	516:529	fermented food	516:529	In addition, the improving mechanisms of fermented food were investigated.					
37031963	2	16	theme	fermented	369:377	arg1	food					379:382	a fermented food	367:382	a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria	367:472	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	2	16	theme	fermented	369:377	arg1	helpful					392:398	helpful	392:398	helpful	392:398	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	4	17	theme	TK1501	655:660	arg1	soybeans					672:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	8	18	theme	mucin-2	1252:1258	arg1	expression					1260:1269	the mucin-2 expression	1248:1269	the mucin-2 expression	1248:1269	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
37031963	6	19	theme	live	890:893	arg1	bacteria					903:910	live or dead bacteria	890:910	bacterial metabolites but not live or dead bacteria	860:910	However, the efficacy was associated with bacterial metabolites but not live or dead bacteria.					
37031963	5	20	theme	TK1501	773:778	arg1	soybean					790:796	TK1501 fermented soybean	773:796	TK1501 fermented soybean	773:796	RESULTS In this study, TK1501 fermented soybean alleviated colitis.					
37031963	3	21	theme	food	526:529	arg1	mechanisms					502:511	the improving mechanisms	488:511	the improving mechanisms of fermented food	488:529	In addition, the improving mechanisms of fermented food were investigated.					
37031963	9	22	theme	cell	1274:1277	arg1	experiment					1279:1288	A cell experiment	1272:1288	A cell experiment	1272:1288	A cell experiment displayed that lipoteichoic acid could enhance the phagocytosis of macrophages.					
37031963	1	23	theme	live	210:213	arg1	bacteria					215:222	live bacteria	210:222	live bacteria	210:222	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	0	24	theme	Lactobacillus	0:12	arg1	soybeans					41:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	4	25	theme	Dextran	550:556	arg1	sodium					566:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	10	26	theme	TK1501	1469:1474	arg1	peptidoglycan					1512:1524	peptidoglycan	1512:1524	peptidoglycan	1512:1524	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	10	26	theme	TK1501	1469:1474	arg1	metabolites					1454:1464	metabolites	1454:1464	metabolites of TK1501	1454:1474	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	10	26	theme	TK1501	1469:1474	arg1	acid					1503:1506	lipoteichoic acid	1490:1506	lipoteichoic acid	1490:1506	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	4	27	theme	bowel	735:739	arg1	disease					741:747	inflammatory bowel disease	722:747	inflammatory bowel disease	722:747	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	11	28	theme	fermented	1531:1539	arg1	food					1541:1544	The fermented food	1527:1544	The fermented food	1527:1544	The fermented food may have a long shelf life and lax storage condition.					
37031963	4	29	theme	fermented	662:670	arg1	soybeans					672:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	2	30	theme	disease	423:429	arg1	treatment					431:439	inflammatory bowel disease treatment	404:439	inflammatory bowel disease treatment	404:439	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	8	31	theme	main	1096:1099	arg1	ingredient					1108:1117	the main active ingredient	1092:1117	the main active ingredient was lipoteichoic acid and peptidoglycan	1092:1157	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
37031963	7	32	theme	soybean	939:945	arg1	analysis					927:934	Compositional analysis	913:934	Compositional analysis of soybean before and after fermentation	913:975	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	2	33	theme	inflammatory	404:415	arg1	disease					423:429	inflammatory bowel disease	404:429	inflammatory bowel disease treatment	404:439	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	2	34	theme	bowel	417:421	arg1	disease					423:429	inflammatory bowel disease	404:429	inflammatory bowel disease treatment	404:439	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	3	35	theme	improving	492:500	arg1	mechanisms					502:511	the improving mechanisms	488:511	the improving mechanisms of fermented food	488:529	In addition, the improving mechanisms of fermented food were investigated.					
37031963	2	36	theme	bacteria	465:472	arg1	independent					445:455	independent	445:455	independent	445:455	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	4	37	theme	sulfate	558:564	arg1	sodium					566:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	11	38	theme	shelf	1562:1566	arg1	life					1568:1571	a long shelf life	1555:1571	a long shelf life	1555:1571	The fermented food may have a long shelf life and lax storage condition.					
37031963	4	39	dep	Lactobacillus	631:643	arg1	paracasei					645:653	paracasei	645:653	paracasei	645:653	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	4	40	theme	Lactobacillus	631:643	arg1	soybeans					672:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Lactobacillus paracasei TK1501 fermented soybeans	631:679	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	2	41	theme	live	460:463	arg1	bacteria					465:472	live bacteria	460:472	live bacteria	460:472	For those problems, we try to find a fermented food that is helpful for inflammatory bowel disease treatment but independent of live bacteria.					
37031963	5	42	theme	fermented	780:788	arg1	soybean					790:796	TK1501 fermented soybean	773:796	TK1501 fermented soybean	773:796	RESULTS In this study, TK1501 fermented soybean alleviated colitis.					
37031963	6	43	theme	bacterial	860:868	arg1	metabolites					870:880	bacterial metabolites	860:880	bacterial metabolites but not live or dead bacteria	860:910	However, the efficacy was associated with bacterial metabolites but not live or dead bacteria.					
37031963	0	44	theme	fermented	31:39	arg1	soybeans					41:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans	0:48	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	1	45	theme	shelf	233:237	arg1	short					247:251	short	247:251	short	247:251	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	1	45	theme	shelf	233:237	arg1	life					239:242	the shelf life	229:242	the shelf life	229:242	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	0	46	theme	sulfate	68:74	arg1	colitis					91:97	dextran sulfate sodium-induced colitis	60:97	dextran sulfate sodium-induced colitis	60:97	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	8	47	theme	lipoteichoic	1123:1134	arg1	acid					1136:1139	lipoteichoic acid	1123:1139	lipoteichoic acid	1123:1139	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
37031963	4	48	from	disease	610:616	arg1	mice					621:624	mice	621:624	mice	621:624	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	1	49	theme	BACKGROUNG	139:148	arg1	food					160:163	BACKGROUNG Probiotic food	139:163	BACKGROUNG Probiotic food	139:163	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	0	50	theme	dextran	60:66	arg1	sulfate					68:74	dextran sulfate	60:74	dextran sulfate sodium-induced colitis	60:97	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	5	51	dep	RESULTS	750:756	arg1	alleviated					798:807	alleviated	798:807	alleviated colitis	798:815	RESULTS In this study, TK1501 fermented soybean alleviated colitis.					
37031963	11	52	contain	have	1550:1553	arg2	life					1568:1571	a long shelf life	1555:1571	a long shelf life	1555:1571	The fermented food may have a long shelf life and lax storage condition.					
37031963	11	52	contain	have	1550:1553	arg1	food					1541:1544	The fermented food	1527:1544	The fermented food	1527:1544	The fermented food may have a long shelf life and lax storage condition.					
37031963	10	53	dep	CONCLUSION	1370:1379	arg1	general					1384:1390	general	1384:1390	general	1384:1390	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	1	54	theme	Probiotic	150:158	arg1	food					160:163	BACKGROUNG Probiotic food	139:163	BACKGROUNG Probiotic food	139:163	BACKGROUNG Probiotic food is healthy to regulate intestinal floras via live bacteria, but the shelf life is short and the preservation condition is demanding due to the bacteria being fragile.					
37031963	7	55	theme	Compositional	913:925	arg1	analysis					927:934	Compositional analysis	913:934	Compositional analysis of soybean before and after fermentation	913:975	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	7	56	theme	bacteria	1020:1027	arg1	growth					1029:1034	bacteria growth	1020:1034	bacteria growth	1020:1034	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	4	57	theme	inflammatory	722:733	arg1	disease					741:747	inflammatory bowel disease	722:747	inflammatory bowel disease	722:747	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	10	58	theme	soybean	1410:1416	arg1	colitis					1430:1436	TK1501 fermented soybean alleviating colitis	1393:1436	TK1501 fermented soybean alleviating colitis	1393:1436	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	4	59	theme	bowel	604:608	arg1	disease					610:616	inflammatory bowel disease	591:616	inflammatory bowel disease in mice	591:624	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	4	60	used	used	577:580	arg2	sodium					566:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium	550:571	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	9	61	theme	lipoteichoic	1305:1316	arg1	acid					1318:1321	lipoteichoic acid	1305:1321	lipoteichoic acid	1305:1321	A cell experiment displayed that lipoteichoic acid could enhance the phagocytosis of macrophages.					
37031963	4	62	theme	inflammatory	591:602	arg1	disease					610:616	inflammatory bowel disease	591:616	inflammatory bowel disease in mice	591:624	Dextran sulfate sodium was used to model inflammatory bowel disease in mice, and Lactobacillus paracasei TK1501 fermented soybeans and their metabolites were used to treat inflammatory bowel disease.					
37031963	10	63	from	CONCLUSION	1370:1379	arg1	dependent					1441:1449	dependent	1441:1449	dependent	1441:1449	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	10	64	theme	alleviating	1418:1428	arg1	colitis					1430:1436	TK1501 fermented soybean alleviating colitis	1393:1436	TK1501 fermented soybean alleviating colitis	1393:1436	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	11	65	theme	long	1557:1560	arg1	life					1568:1571	a long shelf life	1555:1571	a long shelf life	1555:1571	The fermented food may have a long shelf life and lax storage condition.					
37031963	10	66	from	dependent	1441:1449	arg1	CONCLUSION					1370:1379	CONCLUSION	1370:1379	CONCLUSION	1370:1379	CONCLUSION In general, TK1501 fermented soybean alleviating colitis is dependent on metabolites of TK1501, particularly lipoteichoic acid and peptidoglycan.					
37031963	0	67	theme	sodium-induced	76:89	arg1	colitis					91:97	dextran sulfate sodium-induced colitis	60:97	dextran sulfate sodium-induced colitis	60:97	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	0	68	dep	Lactobacillus	0:12	arg1	paracasei					14:22	paracasei	14:22	paracasei	14:22	Lactobacillus paracasei TK1501 fermented soybeans alleviate dextran sulfate sodium-induced colitis by regulating intestinal cell function.					
37031963	7	69	theme	soy	988:990	arg1	carbohydrates					992:1004	soy carbohydrates	988:1004	soy carbohydrates	988:1004	Compositional analysis of soybean before and after fermentation shows that soy carbohydrates were used for bacteria growth and produced functional substances.					
37031963	8	70	theme	active	1101:1106	arg1	ingredient					1108:1117	the main active ingredient	1092:1117	the main active ingredient was lipoteichoic acid and peptidoglycan	1092:1157	Further, we display the main active ingredient was lipoteichoic acid and peptidoglycan, because lipoteichoic acid reduced the colonic macrophage and peptidoglycan may increase the mucin-2 expression.					
36610579	1	0	theme	lactic	280:285	arg1	acid					287:290	lactic acid	280:290	lactic acid (LA)	280:295	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	0	theme	lactic	280:285	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	0	theme	lactic	280:285	arg1	LA					293:294	LA	293:294	LA	293:294	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	1	theme	methane	230:236	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	1	theme	methane	230:236	arg1	MSA					253:255	MSA	253:255	MSA	253:255	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	1	theme	methane	230:236	arg1	acid					247:250	methane sulfonic acid	230:250	methane sulfonic acid (MSA)	230:256	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	5	2	theme	ABTS	949:952	arg1	radical					954:960	ABTS radical	949:960	ABTS radical	949:960	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	3	3	theme	carbohydrates	553:565	arg1	terms					538:542	terms	538:542	terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %)	538:620	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	7	4	theme	organic	1064:1070	arg1	acids					1072:1076	organic acids	1064:1076	organic acids	1064:1076	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	7	4	theme	organic	1064:1070	arg1	candidates					1086:1095	good candidates	1081:1095	good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1081:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	1	5	theme	sulfonic	238:245	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	5	theme	sulfonic	238:245	arg1	MSA					253:255	MSA	253:255	MSA	253:255	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	5	theme	sulfonic	238:245	arg1	acid					247:250	methane sulfonic acid	230:250	methane sulfonic acid (MSA)	230:256	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	4	6	dep	SA	758:759	arg1	agents					787:792	precipitating agents	773:792	precipitating agents	773:792	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	2	7	theme	extract/g	471:479	arg1	SCB					481:483	14.5 g extract/g SCB	464:483	14.5 g extract/g SCB	464:483	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	2	7	theme	extract/g	471:479	arg1	SCB					459:461	SCB	459:461	SCB (14.5 g extract/g SCB)	459:484	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	7	8	theme	conventional	1181:1192	arg1	acid					1203:1206	the conventional sulfuric acid	1177:1206	the conventional sulfuric acid	1177:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	6	9	theme	bioactive	1025:1033	arg1	extracts					1035:1042	recover lignin bioactive extracts	1010:1042	recover lignin bioactive extracts	1010:1042	FA was the most promising alternative to SA to recover lignin bioactive extracts.					
36610579	3	10	from	similar	512:518	arg1	terms					538:542	terms	538:542	terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %)	538:620	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	3	10	from	similar	512:518	arg1	composition					523:533	composition	523:533	composition	523:533	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	3	11	theme	lignin	578:583	arg1	terms					538:542	terms	538:542	terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %)	538:620	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	2	12	theme	14.5 g	464:469	arg1	SCB					481:483	14.5 g extract/g SCB	464:483	14.5 g extract/g SCB	464:483	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	2	12	theme	14.5 g	464:469	arg1	SCB					459:461	SCB	459:461	SCB (14.5 g extract/g SCB)	459:484	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	1	13	theme	common	343:348	arg1	one					350:352	the most common one	334:352	the most common one used in industry	334:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	13	theme	common	343:348	arg1	acid					323:326	sulfuric acid	314:326	sulfuric acid (SA)	314:331	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	7	14	theme	biomass	1251:1257	arg1	valorization					1259:1270	this biomass valorization	1246:1270	this biomass valorization	1246:1270	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	2	15	theme	precipitation	404:416	arg1	yield					418:422	the highest precipitation yield	392:422	the highest precipitation yield	392:422	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	7	16	theme	alkaline	1134:1141	arg1	pulping					1143:1149	alkaline pulping	1134:1149	alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1134:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	4	17	located	observed	741:748	arg2	differences					709:719	differences	709:719	differences in composition	709:734	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	4	17	located	observed	741:748	arg1	terms					811:815	terms	811:815	terms of sugar content	811:832	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	1	18	theme	straw	159:163	arg1	liquors					186:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors	131:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	131:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	2	19	theme	highest	396:402	arg1	yield					418:422	the highest precipitation yield	392:422	the highest precipitation yield	392:422	Results showed that the highest precipitation yield was achieved by LA when applied to SCB (14.5 g extract/g SCB).					
36610579	4	20	theme	sugar	820:824	arg1	content					826:832	sugar content	820:832	sugar content	820:832	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	5	21	from	scavenging	935:944	arg1	extracts					899:906	the extracts	895:906	the extracts	895:906	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	5	21	from	scavenging	935:944	arg1	effective					918:926	effective	918:926	effective	918:926	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	0	22	theme	value-added	5:15	arg1	lignin					17:22	High value-added lignin	0:22	High value-added lignin	0:22	High value-added lignin extracts from sugarcane by-products.					
36610579	0	23	theme	High	0:3	arg1	lignin					17:22	High value-added lignin	0:22	High value-added lignin	0:22	High value-added lignin extracts from sugarcane by-products.					
36610579	7	24	theme	green	1227:1231	arg1	solution					1233:1240	a green solution	1225:1240	a green solution for this biomass valorization	1225:1270	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	5	25	theme	radical	954:960	arg1	scavenging					935:944	the scavenging	931:944	the scavenging of ABTS radical	931:960	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	5	26	from	effective	918:926	arg1	scavenging					935:944	the scavenging	931:944	the scavenging of ABTS radical	931:960	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	7	27	theme	SCS	1162:1164	arg1	pulping					1143:1149	alkaline pulping	1134:1149	alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1134:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	7	28	theme	sulfuric	1194:1201	arg1	acid					1203:1206	the conventional sulfuric acid	1177:1206	the conventional sulfuric acid	1177:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	1	29	theme	lignin	100:105	arg1	extracts					117:124	lignin bioactive extracts	100:124	lignin bioactive extracts	100:124	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	30	theme	alkaline	171:178	arg1	liquors					186:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors	131:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	131:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	FA					272:273	FA	272:273	FA	272:273	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	LA					293:294	LA	293:294	LA	293:294	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	MSA					253:255	MSA	253:255	MSA	253:255	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	acid					287:290	lactic acid	280:290	lactic acid (LA)	280:295	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	acid					247:250	methane sulfonic acid	230:250	methane sulfonic acid (MSA)	230:256	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	31	dep	agents	222:227	arg1	acid					266:269	formic acid	259:269	formic acid (FA)	259:274	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	32	theme	bioactive	107:115	arg1	extracts					117:124	lignin bioactive extracts	100:124	lignin bioactive extracts	100:124	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	33	theme	black	180:184	arg1	liquors					186:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors	131:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	131:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	0	34	theme	sugarcane	38:46	arg1	by-products					48:58	sugarcane by-products	38:58	sugarcane by-products	38:58	High value-added lignin extracts from sugarcane by-products.					
36610579	1	35	theme	formic	259:264	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	35	theme	formic	259:264	arg1	FA					272:273	FA	272:273	FA	272:273	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	35	theme	formic	259:264	arg1	acid					266:269	formic acid	259:269	formic acid (FA)	259:274	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	7	36	theme	acid	1203:1206	arg1	pulping					1143:1149	alkaline pulping	1134:1149	alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1134:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	7	37	theme	valuable	1111:1118	arg1	extracts					1120:1127	valuable extracts	1111:1127	valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1111:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	7	38	theme	SCB	1154:1156	arg1	pulping					1143:1149	alkaline pulping	1134:1149	alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1134:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	1	39	theme	sulfuric	314:321	arg1	one					350:352	the most common one	334:352	the most common one used in industry	334:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	39	theme	sulfuric	314:321	arg1	SA					329:330	SA	329:330	SA	329:330	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	39	theme	sulfuric	314:321	arg1	acid					323:326	sulfuric acid	314:326	sulfuric acid (SA)	314:331	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	4	40	theme	SCS	637:639	arg1	extracts					641:648	the SCS extracts	633:648	the SCS extracts	633:648	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	1	41	from	liquors	186:192	arg1	production					86:95	the production	82:95	the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	82:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	3	42	from	composition	523:533	arg1	similar					512:518	similar	512:518	similar	512:518	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	1	43	theme	acid	323:326	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	43	theme	acid	323:326	arg1	replacers					301:309	replacers	301:309	replacers of sulfuric acid (SA), the most common one used in industry	301:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	4	44	theme	similar	651:657	arg1	yields					659:664	similar yields	651:664	similar yields	651:664	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	1	45	theme	extracts	117:124	arg1	production					86:95	the production	82:95	the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	82:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	4	46	theme	content	826:832	arg1	terms					811:815	terms	811:815	terms of sugar content	811:832	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	3	47	theme	inorganics	599:608	arg1	terms					538:542	terms	538:542	terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %)	538:620	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	5	48	theme	scavenging	866:875	arg1	activity					877:884	radical scavenging activity	858:884	radical scavenging activity	858:884	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	5	49	theme	radical	858:864	arg1	activity					877:884	radical scavenging activity	858:884	radical scavenging activity	858:884	All extracts exhibited radical scavenging activity; overall the extracts were more effective in the scavenging of ABTS radical.					
36610579	3	50	theme	total	547:551	arg1	carbohydrates					553:565	total carbohydrates	547:565	total carbohydrates (61-70 %)	547:575	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	3	50	theme	total	547:551	arg1	%					574:574	61-70 %	568:574	61-70 %	568:574	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	3	51	theme	SCB	494:496	arg1	extracts					498:505	Lignin SCB extracts	487:505	Lignin SCB extracts	487:505	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	1	52	theme	sugarcane	131:139	arg1	SCB					150:152	SCB	150:152	SCB	150:152	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	52	theme	sugarcane	131:139	arg1	bagasse					141:147	sugarcane bagasse	131:147	sugarcane bagasse (SCB)	131:153	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	53	theme	greener	200:206	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	53	theme	greener	200:206	arg1	acid					287:290	lactic acid	280:290	lactic acid (LA)	280:295	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	53	theme	greener	200:206	arg1	replacers					301:309	replacers	301:309	replacers of sulfuric acid (SA), the most common one used in industry	301:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	53	theme	greener	200:206	arg1	acid					247:250	methane sulfonic acid	230:250	methane sulfonic acid (MSA)	230:256	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	53	theme	greener	200:206	arg1	acid					266:269	formic acid	259:269	formic acid (FA)	259:274	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	6	54	theme	promising	979:987	arg1	alternative					989:999	the most promising alternative	970:999	the most promising alternative to SA to recover lignin bioactive extracts	970:1042	FA was the most promising alternative to SA to recover lignin bioactive extracts.					
36610579	6	54	theme	promising	979:987	arg1	FA					963:964	FA	963:964	FA	963:964	FA was the most promising alternative to SA to recover lignin bioactive extracts.					
36610579	4	55	from	differences	709:719	arg1	composition					724:734	composition	724:734	composition	724:734	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
36610579	6	56	theme	lignin	1018:1023	arg1	extracts					1035:1042	recover lignin bioactive extracts	1010:1042	recover lignin bioactive extracts	1010:1042	FA was the most promising alternative to SA to recover lignin bioactive extracts.					
36610579	7	57	from	pulping	1143:1149	arg1	extracts					1120:1127	valuable extracts	1111:1127	valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1111:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	1	58	theme	bagasse	141:147	arg1	liquors					186:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors	131:192	sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry	131:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	59	theme	precipitating	208:220	arg1	agents					222:227	greener precipitating agents	200:227	greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA))	200:296	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	59	theme	precipitating	208:220	arg1	acid					287:290	lactic acid	280:290	lactic acid (LA)	280:295	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	59	theme	precipitating	208:220	arg1	replacers					301:309	replacers	301:309	replacers of sulfuric acid (SA), the most common one used in industry	301:369	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	59	theme	precipitating	208:220	arg1	acid					247:250	methane sulfonic acid	230:250	methane sulfonic acid (MSA)	230:256	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	1	59	theme	precipitating	208:220	arg1	acid					266:269	formic acid	259:269	formic acid (FA)	259:274	This study evaluates the production of lignin bioactive extracts from sugarcane bagasse (SCB) and straw (SCS) alkaline black liquors using greener precipitating agents (methane sulfonic acid (MSA), formic acid (FA) and lactic acid (LA)) as replacers of sulfuric acid (SA), the most common one used in industry.					
36610579	6	60	theme	recover	1010:1016	arg1	extracts					1035:1042	recover lignin bioactive extracts	1010:1042	recover lignin bioactive extracts	1010:1042	FA was the most promising alternative to SA to recover lignin bioactive extracts.					
36610579	3	61	from	terms	538:542	arg1	similar					512:518	similar	512:518	similar	512:518	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	3	62	theme	Lignin	487:492	arg1	extracts					498:505	Lignin SCB extracts	487:505	Lignin SCB extracts	487:505	Lignin SCB extracts were similar in composition in terms of total carbohydrates (61-70 %), lignin (22-30 %) and inorganics (1.6-2.6 %).					
36610579	7	63	theme	good	1081:1084	arg1	acids					1072:1076	organic acids	1064:1076	organic acids	1064:1076	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	7	63	theme	good	1081:1084	arg1	candidates					1086:1095	good candidates	1081:1095	good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid	1081:1206	This work suggests organic acids as good candidates for obtaining valuable extracts from alkaline pulping of SCB and SCS instead of the conventional sulfuric acid, thus suggesting a green solution for this biomass valorization.					
36610579	4	64	theme	precipitating	773:785	arg1	agents					787:792	precipitating agents	773:792	precipitating agents	773:792	Regarding the SCS extracts, similar yields were obtained among all extracts, however; differences in composition were observed between SA and greener precipitating agents, particularly in terms of sugar content.					
37062377	6	0	from	isotherms	897:905	arg1	MPB-ALG-1					925:933	MPB-ALG-1	925:933	MPB-ALG-1	925:933	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	4	1	theme	contact	595:601	arg1	time					603:606	contact time	595:606	contact time	595:606	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	9	2	theme	MPB-ALG-1	1275:1283	arg1	beads					1285:1289	MPB-ALG-1 beads	1275:1289	MPB-ALG-1 beads	1275:1289	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	9	2	theme	MPB-ALG-1	1275:1283	arg1	friendly					1325:1332	an environmentally friendly	1306:1332	an environmentally friendly	1306:1332	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	9	2	theme	MPB-ALG-1	1275:1283	arg1	adsorbent					1348:1356	adsorbent	1348:1356	adsorbent	1348:1356	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	0	3	theme	adsorbent	79:87	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	3	theme	adsorbent	79:87	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	1	4	theme	facile	292:297	arg1	method					299:304	a facile method	290:304	a facile method	290:304	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	9	5	theme	environmentally	1309:1323	arg1	beads					1285:1289	MPB-ALG-1 beads	1275:1289	MPB-ALG-1 beads	1275:1289	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	9	5	theme	environmentally	1309:1323	arg1	friendly					1325:1332	an environmentally friendly	1306:1332	an environmentally friendly	1306:1332	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	0	6	link	shell-derived	21:33	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	6	link	shell-derived	21:33	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	1	7	theme	H2O2	212:215	arg1	MPB					256:258	MPB	256:258	MPB	256:258	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	7	theme	H2O2	212:215	arg1	biochar					247:253	H2O2 modified peanut shell-derived biochar	212:253	H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix	212:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	5	8	from	pH 5	809:812	arg1	capacity					727:734	the maximum adsorption capacity	704:734	the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	704:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	8	from	pH 5	809:812	arg1	117.4 mg g-1					793:804	117.4 mg g-1	793:804	117.4 mg g-1	793:804	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	9	9	from	wastewater	1389:1398	arg1	removal					1366:1372	the removal	1362:1372	the removal of Cu(II) from wastewater	1362:1398	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	1	10	theme	modified	217:224	arg1	MPB					256:258	MPB	256:258	MPB	256:258	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	10	theme	modified	217:224	arg1	biochar					247:253	H2O2 modified peanut shell-derived biochar	212:253	H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix	212:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	4	11	theme	coexisting	635:644	arg1	ions					646:649	coexisting ions	635:649	coexisting ions	635:649	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	3	12	theme	adsorption	470:479	arg1	performance					481:491	Cu(II) adsorption performance	463:491	Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG	463:538	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	1	13	theme	peanut	226:231	arg1	MPB					256:258	MPB	256:258	MPB	256:258	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	13	theme	peanut	226:231	arg1	biochar					247:253	H2O2 modified peanut shell-derived biochar	212:253	H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix	212:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	2	14	theme	materials	348:356	arg1	properties					325:334	properties	325:334	properties	325:334	The structure and properties of prepared materials were characterized using FTIR, BET, SEM, and XPS.					
37062377	2	14	theme	materials	348:356	arg1	structure					311:319	structure	311:319	structure	311:319	The structure and properties of prepared materials were characterized using FTIR, BET, SEM, and XPS.					
37062377	0	15	theme	Cu	104:105	arg1	removal					93:99	removal	93:99	removal of Cu(II) from aqueous solution	93:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	8	16	theme	MPB-ALG-1	1176:1184	arg1	beads					1186:1190	MPB-ALG-1 beads	1176:1190	MPB-ALG-1 beads	1176:1190	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	9	17	theme	Cu	1377:1378	arg1	removal					1366:1372	the removal	1362:1372	the removal of Cu(II) from wastewater	1362:1398	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	2	18	dep	structure	311:319	arg1	The					307:309	The	307:309	The	307:309	The structure and properties of prepared materials were characterized using FTIR, BET, SEM, and XPS.					
37062377	2	19	theme	prepared	339:346	arg1	materials					348:356	prepared materials	339:356	prepared materials	339:356	The structure and properties of prepared materials were characterized using FTIR, BET, SEM, and XPS.					
37062377	5	20	theme	maximum	708:714	arg1	capacity					727:734	the maximum adsorption capacity	704:734	the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	704:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	20	theme	maximum	708:714	arg1	117.4 mg g-1					793:804	117.4 mg g-1	793:804	117.4 mg g-1	793:804	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	6	21	from	kinetics	884:891	arg1	MPB-ALG-1					925:933	MPB-ALG-1	925:933	MPB-ALG-1	925:933	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	3	22	theme	MPB	496:498	arg1	performance					481:491	Cu(II) adsorption performance	463:491	Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG	463:538	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	0	23	from	solution	124:131	arg1	removal					93:99	removal	93:99	removal of Cu(II) from aqueous solution	93:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	5	24	theme	adsorption	716:725	arg1	capacity					727:734	the maximum adsorption capacity	704:734	the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	704:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	24	theme	adsorption	716:725	arg1	117.4 mg g-1					793:804	117.4 mg g-1	793:804	117.4 mg g-1	793:804	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	1	25	theme	shell-derived	233:245	arg1	MPB					256:258	MPB	256:258	MPB	256:258	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	25	theme	shell-derived	233:245	arg1	biochar					247:253	H2O2 modified peanut shell-derived biochar	212:253	H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix	212:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	4	26	theme	initial	609:615	arg1	concentration					617:629	initial concentration	609:629	initial concentration	609:629	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	5	27	theme	MPB/alginate = 1:1	764:781	arg1	MPB-ALG-1					753:761	the optimized MPB-ALG-1	739:761	the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	739:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	27	theme	MPB/alginate = 1:1	764:781	arg1	%					786:786	MPB/alginate = 1:1 w/w%	764:786	MPB/alginate = 1:1 w/w%	764:786	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	8	28	theme	XPS	1218:1220	arg1	analysis					1222:1229	FTIR and XPS analysis	1209:1229	analysis	1222:1229	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	1	29	theme	novel	151:155	arg1	bead					167:170	a novel composite bead	149:170	a novel composite bead (MPB-ALG)	149:180	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	29	theme	novel	151:155	arg1	MPB-ALG					173:179	MPB-ALG	173:179	MPB-ALG	173:179	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	0	30	theme	shell-derived	21:33	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	30	theme	shell-derived	21:33	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	1	31	theme	composite	157:165	arg1	bead					167:170	a novel composite bead	149:170	a novel composite bead (MPB-ALG)	149:180	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	31	theme	composite	157:165	arg1	MPB-ALG					173:179	MPB-ALG	173:179	MPB-ALG	173:179	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	0	32	theme	peanut	14:19	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	32	theme	peanut	14:19	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	6	33	dep	kinetics	884:891	arg1	data					907:910	data	907:910	data	907:910	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	8	34	from	mechanisms	1152:1161	arg1	beads					1186:1190	MPB-ALG-1 beads	1176:1190	MPB-ALG-1 beads	1176:1190	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	5	35	theme	optimized	743:751	arg1	MPB-ALG-1					753:761	the optimized MPB-ALG-1	739:761	the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	739:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	35	theme	optimized	743:751	arg1	%					786:786	MPB/alginate = 1:1 w/w%	764:786	MPB/alginate = 1:1 w/w%	764:786	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	0	36	theme	composite	52:60	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	36	theme	composite	52:60	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	8	37	theme	Cu	1166:1167	arg1	mechanisms					1152:1161	the adsorption mechanisms	1137:1161	the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads	1137:1190	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	0	38	theme	aqueous	116:122	arg1	solution					124:131	aqueous solution	116:131	aqueous solution	116:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	3	39	theme	beads	516:520	arg1	performance					481:491	Cu(II) adsorption performance	463:491	Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG	463:538	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	4	40	theme	components	570:579	arg1	ions					646:649	coexisting ions	635:649	coexisting ions	635:649	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	4	40	theme	components	570:579	arg1	parameters					552:561	The effect parameters	541:561	The effect parameters of the components	541:579	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	4	40	theme	components	570:579	arg1	pH					591:592	solution pH	582:592	solution pH	582:592	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	4	40	theme	components	570:579	arg1	time					603:606	contact time	595:606	contact time	595:606	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	4	40	theme	components	570:579	arg1	concentration					617:629	initial concentration	609:629	initial concentration	609:629	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	5	41	theme	MPB-ALG-1	753:761	arg1	capacity					727:734	the maximum adsorption capacity	704:734	the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	704:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	41	theme	MPB-ALG-1	753:761	arg1	117.4 mg g-1					793:804	117.4 mg g-1	793:804	117.4 mg g-1	793:804	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	0	42	theme	biochar/alginate	35:50	arg1	beads					62:66	peanut shell-derived biochar/alginate composite beads	14:66	peanut shell-derived biochar/alginate composite beads	14:66	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	0	42	theme	biochar/alginate	35:50	arg1	green					73:77	a green	71:77	a green adsorbent for removal of Cu(II) from aqueous solution	71:131	H2O2 modified peanut shell-derived biochar/alginate composite beads as a green adsorbent for removal of Cu(II) from aqueous solution.					
37062377	9	43	used	used	1298:1301	arg2	adsorbent					1348:1356	adsorbent	1348:1356	adsorbent	1348:1356	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	9	43	used	used	1298:1301	arg2	beads					1285:1289	MPB-ALG-1 beads	1275:1289	MPB-ALG-1 beads	1275:1289	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	9	43	used	used	1298:1301	arg2	friendly					1325:1332	an environmentally friendly	1306:1332	an environmentally friendly	1306:1332	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	6	44	theme	adsorption	873:882	arg1	kinetics					884:891	The adsorption kinetics	869:891	The adsorption kinetics	869:891	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	7	45	theme	plain	1030:1034	arg1	beads					1040:1044	plain ALG beads	1030:1044	plain ALG beads	1030:1044	Compared with plain ALG beads, MPB-ALG-1 exhibited better reusability and anti-interference of coexisting ions.					
37062377	4	46	theme	effect	545:550	arg1	parameters					552:561	The effect parameters	541:561	The effect parameters of the components	541:579	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	3	47	theme	plain	501:505	arg1	beads					516:520	plain alginate beads	501:520	plain alginate beads (ALG)	501:526	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	3	47	theme	plain	501:505	arg1	ALG					523:525	ALG	523:525	ALG	523:525	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	6	48	theme	Elovich	958:964	arg1	model					974:978	Elovich kinetic model	958:978	Elovich kinetic model	958:978	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	6	49	theme	adsorption	995:1004	arg1	isotherm					1006:1013	Freundlich adsorption isotherm	984:1013	Freundlich adsorption isotherm	984:1013	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	1	50	theme	alginate	266:273	arg1	matrix					275:280	alginate matrix	266:280	alginate matrix	266:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	3	51	theme	alginate	507:514	arg1	beads					516:520	plain alginate beads	501:520	plain alginate beads (ALG)	501:526	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	3	51	theme	alginate	507:514	arg1	ALG					523:525	ALG	523:525	ALG	523:525	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	6	52	theme	Freundlich	984:993	arg1	isotherm					1006:1013	Freundlich adsorption isotherm	984:1013	Freundlich adsorption isotherm	984:1013	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	4	53	theme	solution	582:589	arg1	pH					591:592	solution pH	582:592	solution pH	582:592	The effect parameters of the components, solution pH, contact time, initial concentration and coexisting ions were studied systematically.					
37062377	3	54	theme	Batch	408:412	arg1	experiments					425:435	Batch adsorption experiments	408:435	Batch adsorption experiments	408:435	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	9	55	theme	experimental	1236:1247	arg1	results					1249:1255	The experimental results	1232:1255	The experimental results	1232:1255	The experimental results demonstrated that MPB-ALG-1 beads can be used as an environmentally friendly and efficient adsorbent for the removal of Cu(II) from wastewater.					
37062377	8	56	theme	FTIR	1209:1212	arg1	analysis					1222:1229	FTIR and XPS analysis	1209:1229	analysis	1222:1229	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	3	57	theme	MPB-ALG	532:538	arg1	performance					481:491	Cu(II) adsorption performance	463:491	Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG	463:538	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	3	58	theme	adsorption	414:423	arg1	experiments					425:435	Batch adsorption experiments	408:435	Batch adsorption experiments	408:435	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	6	59	theme	Cu	915:916	arg1	isotherms					897:905	isotherms	897:905	isotherms	897:905	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	6	59	theme	Cu	915:916	arg1	kinetics					884:891	The adsorption kinetics	869:891	The adsorption kinetics	869:891	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	8	60	theme	adsorption	1141:1150	arg1	mechanisms					1152:1161	the adsorption mechanisms	1137:1161	the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads	1137:1190	Finally, the adsorption mechanisms of Cu(II) on MPB-ALG-1 beads were revealed by FTIR and XPS analysis.					
37062377	6	61	theme	kinetic	966:972	arg1	model					974:978	Elovich kinetic model	958:978	Elovich kinetic model	958:978	The adsorption kinetics and isotherms data of Cu(II) on MPB-ALG-1 were well described by Elovich kinetic model and Freundlich adsorption isotherm.					
37062377	5	62	theme	w/w	783:785	arg1	MPB-ALG-1					753:761	the optimized MPB-ALG-1	739:761	the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%)	739:787	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	5	62	theme	w/w	783:785	arg1	%					786:786	MPB/alginate = 1:1 w/w%	764:786	MPB/alginate = 1:1 w/w%	764:786	The results showed that the maximum adsorption capacity of the optimized MPB-ALG-1 (MPB/alginate = 1:1 w/w%) was 117.4 mg g-1 at pH 5, which was much higher than that of MPB (37.4 mg g-1).					
37062377	7	63	theme	coexisting	1111:1120	arg1	ions					1122:1125	coexisting ions	1111:1125	coexisting ions	1111:1125	Compared with plain ALG beads, MPB-ALG-1 exhibited better reusability and anti-interference of coexisting ions.					
37062377	7	64	theme	ALG	1036:1038	arg1	beads					1040:1044	plain ALG beads	1030:1044	plain ALG beads	1030:1044	Compared with plain ALG beads, MPB-ALG-1 exhibited better reusability and anti-interference of coexisting ions.					
37062377	1	65	link	shell-derived	233:245	arg1	MPB					256:258	MPB	256:258	MPB	256:258	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	1	65	link	shell-derived	233:245	arg1	biochar					247:253	H2O2 modified peanut shell-derived biochar	212:253	H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix	212:280	In this study, a novel composite bead (MPB-ALG) was prepared by encapsulating H2O2 modified peanut shell-derived biochar (MPB) into alginate matrix through a facile method.					
37062377	3	66	theme	Cu	463:464	arg1	performance					481:491	Cu(II) adsorption performance	463:491	Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG	463:538	Batch adsorption experiments were performed to compare Cu(II) adsorption performance of MPB, plain alginate beads (ALG) and MPB-ALG.					
37062377	7	67	theme	ions	1122:1125	arg1	anti-interference					1090:1106	anti-interference	1090:1106	anti-interference	1090:1106	Compared with plain ALG beads, MPB-ALG-1 exhibited better reusability and anti-interference of coexisting ions.					
37062377	7	67	theme	ions	1122:1125	arg1	reusability					1074:1084	reusability	1074:1084	reusability	1074:1084	Compared with plain ALG beads, MPB-ALG-1 exhibited better reusability and anti-interference of coexisting ions.					
35026218	4	0	theme	77.070 mM	596:604	arg1	ratio					559:563	combination ratio	547:563	combination ratio of 1.05	547:571	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	0	theme	77.070 mM	596:604	arg1	pH					534:535	pH	534:535	pH of 5.903	534:544	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	0	theme	77.070 mM	596:604	arg1	strength					584:591	ionic strength	578:591	ionic strength of 77.070 mM	578:604	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	0	theme	77.070 mM	596:604	arg1	conditions					499:508	the optimal preparation conditions	475:508	the optimal preparation conditions for CS-WEG complex	475:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	5	1	theme	rheological	671:681	arg1	properties					683:692	rheological properties	671:692	rheological properties	671:692	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	4	2	theme	preparation	487:497	arg1	pH					534:535	pH	534:535	pH of 5.903	534:544	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	2	theme	preparation	487:497	arg1	conditions					499:508	the optimal preparation conditions	475:508	the optimal preparation conditions for CS-WEG complex	475:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	6	3	theme	complex	977:983	arg1	thinning					937:944	shear thinning	931:944	shear thinning	931:944	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	6	3	theme	complex	977:983	arg1	viscosity					960:968	increased viscosity	950:968	increased viscosity of the complex	950:983	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	8	4	theme	WEG	1312:1314	arg1	production					1298:1307	industrialized production	1283:1307	industrialized production of WEG	1283:1314	This study provides important ideas for improving industrialized production of WEG.					
35026218	2	5	used	used	321:324	arg2	interaction					267:277	electrostatic interaction	253:277	electrostatic interaction between chitosan (CS) and the protein	253:315	In this study, electrostatic interaction between chitosan (CS) and the protein was used to stabilize WEG.					
35026218	1	6	theme	Wheat-embryo	62:73	arg1	WEG					85:87	WEG	85:87	WEG	85:87	Wheat-embryo globulin (WEG) has been shown to confer health benefits, however, it often forms aggregates during industrial production, which decrease its quality and efficacy.					
35026218	1	6	theme	Wheat-embryo	62:73	arg1	globulin					75:82	Wheat-embryo globulin	62:82	Wheat-embryo globulin (WEG)	62:88	Wheat-embryo globulin (WEG) has been shown to confer health benefits, however, it often forms aggregates during industrial production, which decrease its quality and efficacy.					
35026218	4	7	theme	CS-WEG	514:519	arg1	complex					521:527	CS-WEG complex	514:527	CS-WEG complex	514:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	5	8	theme	particle	864:871	arg1	size					873:876	the particle size	860:876	the particle size	860:876	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	9	theme	zeta	801:804	arg1	potential					806:814	the zeta potential	797:814	the zeta potential	797:814	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	10	theme	dispersity	830:839	arg1	index					841:845	poly dispersity index	825:845	poly dispersity index	825:845	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	11	theme	zeta-potential	640:653	arg1	size					665:668	particle size	656:668	particle size	656:668	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	6	12	theme	shear	931:935	arg1	thinning					937:944	shear thinning	931:944	shear thinning	931:944	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	5	13	theme	poly	825:828	arg1	index					841:845	poly dispersity index	825:845	poly dispersity index	825:845	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	4	14	theme	1.05	568:571	arg1	ratio					559:563	combination ratio	547:563	combination ratio of 1.05	547:571	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	14	theme	1.05	568:571	arg1	pH					534:535	pH	534:535	pH of 5.903	534:544	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	14	theme	1.05	568:571	arg1	strength					584:591	ionic strength	578:591	ionic strength of 77.070 mM	578:604	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	14	theme	1.05	568:571	arg1	conditions					499:508	the optimal preparation conditions	475:508	the optimal preparation conditions for CS-WEG complex	475:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	5	15	theme	microscopy	711:720	arg1	characterization					616:631	characterization	616:631	characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite	616:737	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	16	theme	properties	683:692	arg1	characterization					616:631	characterization	616:631	characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite	616:737	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	3	17	theme	WEG	394:396	arg1	lowest					402:407	lowest	402:407	lowest	402:407	Initially, it was observed that the solubility of WEG was lowest in the pH range of 4-5, and its isoelectric point was 4.70.					
35026218	3	17	theme	WEG	394:396	arg1	solubility					380:389	the solubility	376:389	the solubility of WEG	376:396	Initially, it was observed that the solubility of WEG was lowest in the pH range of 4-5, and its isoelectric point was 4.70.					
35026218	7	18	theme	apparent	1100:1107	arg1	viscosity					1109:1117	the apparent viscosity	1096:1117	the apparent viscosity	1096:1117	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	8	19	theme	important	1253:1261	arg1	ideas					1263:1267	important ideas	1253:1267	important ideas	1253:1267	This study provides important ideas for improving industrialized production of WEG.					
35026218	7	20	theme	WEG	1156:1158	arg1	interaction					1141:1151	the electrostatic interaction	1123:1151	the electrostatic interaction	1123:1151	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	7	20	theme	WEG	1156:1158	arg1	viscosity					1109:1117	the apparent viscosity	1096:1117	the apparent viscosity	1096:1117	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	5	21	theme	CS	770:771	arg1	addition					758:765	addition	758:765	addition of CS	758:771	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	22	theme	composite	729:737	arg1	size					665:668	particle size	656:668	particle size	656:668	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	22	theme	composite	729:737	arg1	properties					683:692	rheological properties	671:692	rheological properties	671:692	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	5	22	theme	composite	729:737	arg1	microscopy					711:720	fluorescence microscopy	698:720	fluorescence microscopy	698:720	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	1	23	theme	industrial	174:183	arg1	production					185:194	industrial production	174:194	industrial production	174:194	Wheat-embryo globulin (WEG) has been shown to confer health benefits, however, it often forms aggregates during industrial production, which decrease its quality and efficacy.					
35026218	0	24	theme	storage	18:24	arg1	stability					26:34	storage stability	18:34	storage stability of wheat-embryo globulin	18:59	Chitosan improves storage stability of wheat-embryo globulin.					
35026218	4	25	theme	optimal	479:485	arg1	pH					534:535	pH	534:535	pH of 5.903	534:544	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	25	theme	optimal	479:485	arg1	conditions					499:508	the optimal preparation conditions	475:508	the optimal preparation conditions for CS-WEG complex	475:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	2	26	theme	electrostatic	253:265	arg1	interaction					267:277	electrostatic interaction	253:277	electrostatic interaction between chitosan (CS) and the protein	253:315	In this study, electrostatic interaction between chitosan (CS) and the protein was used to stabilize WEG.					
35026218	4	27	theme	5.903	540:544	arg1	ratio					559:563	combination ratio	547:563	combination ratio of 1.05	547:571	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	27	theme	5.903	540:544	arg1	pH					534:535	pH	534:535	pH of 5.903	534:544	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	27	theme	5.903	540:544	arg1	strength					584:591	ionic strength	578:591	ionic strength of 77.070 mM	578:604	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	4	27	theme	5.903	540:544	arg1	conditions					499:508	the optimal preparation conditions	475:508	the optimal preparation conditions for CS-WEG complex	475:527	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	0	28	theme	wheat-embryo	39:50	arg1	globulin					52:59	wheat-embryo globulin	39:59	wheat-embryo globulin	39:59	Chitosan improves storage stability of wheat-embryo globulin.					
35026218	6	29	theme	dispersion	1004:1013	arg1	stability					1015:1023	the dispersion stability	1000:1023	the dispersion stability	1000:1023	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	8	30	theme	industrialized	1283:1296	arg1	production					1298:1307	industrialized production	1283:1307	industrialized production of WEG	1283:1314	This study provides important ideas for improving industrialized production of WEG.					
35026218	7	31	theme	dispersion	1175:1184	arg1	stability					1186:1194	the dispersion stability	1171:1194	the dispersion stability	1171:1194	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	6	32	theme	increased	950:958	arg1	viscosity					960:968	increased viscosity	950:968	increased viscosity of the complex	950:983	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	5	33	dep	size	665:668	arg1	the					636:638	the	636:638	the	636:638	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	4	34	theme	combination	547:557	arg1	ratio					559:563	combination ratio	547:563	combination ratio of 1.05	547:571	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
35026218	5	35	theme	fluorescence	698:709	arg1	microscopy					711:720	fluorescence microscopy	698:720	fluorescence microscopy	698:720	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	7	36	dep	polymerized	1211:1221	arg1	it					1201:1202	it	1201:1202	it	1201:1202	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	0	37	theme	globulin	52:59	arg1	stability					26:34	storage stability	18:34	storage stability of wheat-embryo globulin	18:59	Chitosan improves storage stability of wheat-embryo globulin.					
35026218	3	38	theme	4-5	428:430	arg1	range					419:423	the pH range	412:423	the pH range of 4-5	412:430	Initially, it was observed that the solubility of WEG was lowest in the pH range of 4-5, and its isoelectric point was 4.70.					
35026218	7	39	with	polymerized	1211:1221	arg1	WEG					1228:1230	WEG	1228:1230	WEG	1228:1230	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	1	40	theme	health	115:120	arg1	benefits					122:129	health benefits	115:129	health benefits	115:129	Wheat-embryo globulin (WEG) has been shown to confer health benefits, however, it often forms aggregates during industrial production, which decrease its quality and efficacy.					
35026218	5	41	theme	certain	883:889	arg1	extent					891:896	a certain extent	881:896	a certain extent	881:896	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	3	42	theme	isoelectric	441:451	arg1	point					453:457	its isoelectric point	437:457	its isoelectric point	437:457	Initially, it was observed that the solubility of WEG was lowest in the pH range of 4-5, and its isoelectric point was 4.70.					
35026218	3	43	theme	pH	416:417	arg1	range					419:423	the pH range	412:423	the pH range of 4-5	412:430	Initially, it was observed that the solubility of WEG was lowest in the pH range of 4-5, and its isoelectric point was 4.70.					
35026218	5	44	theme	particle	656:663	arg1	size					665:668	particle size	656:668	particle size	656:668	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	6	45	theme	CS	921:922	arg1	addition					909:916	addition	909:916	addition of CS	909:922	Moreover, addition of CS caused shear thinning and increased viscosity of the complex, but decreased the dispersion stability over time.					
35026218	7	46	theme	electrostatic	1127:1139	arg1	interaction					1141:1151	the electrostatic interaction	1123:1151	the electrostatic interaction	1123:1151	In summary, these results revealed that CS mainly increased the apparent viscosity and the electrostatic interaction of WEG to improve the dispersion stability when it slowly polymerized with WEG.					
35026218	5	47	theme	size	665:668	arg1	characterization					616:631	characterization	616:631	characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite	616:737	Finally, characterization of the zeta-potential, particle size, rheological properties and fluorescence microscopy of the composite, it was found that addition of CS significantly increased the zeta potential, reduced poly dispersity index, and reduced the particle size to a certain extent.					
35026218	4	48	theme	ionic	578:582	arg1	strength					584:591	ionic strength	578:591	ionic strength of 77.070 mM	578:604	Next, the optimal preparation conditions for CS-WEG complex were pH of 5.903, combination ratio of 1.05, and ionic strength of 77.070 mM.					
36249563	0	0	from	diversity	14:22	arg1	glycome					55:61	fungal glycome	48:61	fungal glycome	48:61	Examining the diversity of structural motifs in fungal glycome.					
36249563	4	1	from	species	833:839	arg1	active					803:808	active	803:808	active	803:808	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	1	2	theme	analysis	130:137	arg1	results					94:100	the results	90:100	the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes	90:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	2	3	theme	degree	463:468	arg1	glycans					364:370	glycans	364:370	glycans	364:370	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	3	theme	degree	463:468	arg1	sizes					432:436	sizes	432:436	sizes of structures, branching degree and net charge	432:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	1	4	from	analysis	130:137	arg1	comparison					164:173	comparison	164:173	comparison with the prokaryotic and protistal glycomes	164:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	3	5	theme	diagnostic	662:671	arg1	tools					673:677	diagnostic tools	662:677	diagnostic tools	662:677	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	4	6	from	active	803:808	arg1	species					833:839	a particular fungal species	813:839	a particular fungal species	813:839	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	2	7	theme	monomeric	326:334	arg1	compositions					348:359	The monomeric and dimeric compositions	322:359	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge	322:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	1	8	theme	scientific	239:248	arg1	literature					250:259	the scientific literature	235:259	the scientific literature	235:259	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	3	9	theme	pathogenic	719:728	arg1	fungi					730:734	pathogenic fungi	719:734	pathogenic fungi	719:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	3	10	theme	obtained	503:510	arg1	information					512:522	The obtained information	499:522	The obtained information	499:522	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	3	11	theme	carbohydrate-based	683:700	arg1	vaccines					702:709	carbohydrate-based vaccines	683:709	carbohydrate-based vaccines against pathogenic fungi	683:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	0	12	theme	motifs	38:43	arg1	diversity					14:22	the diversity	10:22	the diversity of structural motifs in fungal glycome	10:61	Examining the diversity of structural motifs in fungal glycome.					
36249563	2	13	theme	glycans	364:370	arg1	compositions					348:359	The monomeric and dimeric compositions	322:359	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge	322:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	3	14	theme	vaccines	702:709	arg1	development					647:657	the development	643:657	the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	643:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	3	15	theme	molecular	558:566	arg1	markers					568:574	carbohydrate molecular markers	545:574	carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	545:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	1	16	theme	glycome	153:159	arg1	analysis					130:137	a systematic statistical analysis	105:137	a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes	105:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	4	17	theme	particular	815:824	arg1	species					833:839	a particular fungal species	813:839	a particular fungal species	813:839	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	2	18	theme	glycosidic	411:420	arg1	glycans					364:370	glycans	364:370	glycans	364:370	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	18	theme	glycosidic	411:420	arg1	linkages					422:429	glycosidic linkages	411:429	glycosidic linkages	411:429	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	1	19	attach	present	82:88	arg2	we					79:80	we	79:80	we	79:80	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	1	19	attach	present	82:88	arg1	paper					72:76	this paper	67:76	this paper	67:76	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	3	20	theme	carbohydrate	545:556	arg1	markers					568:574	carbohydrate molecular markers	545:574	carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	545:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	2	21	theme	dimeric	340:346	arg1	compositions					348:359	The monomeric and dimeric compositions	322:359	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge	322:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	22	theme	branching	453:461	arg1	degree					463:468	branching degree	453:468	branching degree	453:468	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	1	23	with	comparison	164:173	arg1	glycomes					210:217	the prokaryotic and protistal glycomes	180:217	the prokaryotic and protistal glycomes	180:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	3	24	theme	fungal	588:593	arg1	classes					595:601	various fungal classes	580:601	various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	580:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	2	25	theme	non-carbohydrate	379:394	arg1	glycans					364:370	glycans	364:370	glycans	364:370	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	25	theme	non-carbohydrate	379:394	arg1	modifications					396:408	their non-carbohydrate modifications	373:408	their non-carbohydrate modifications	373:408	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	0	26	theme	structural	27:36	arg1	motifs					38:43	structural motifs	27:43	structural motifs	27:43	Examining the diversity of structural motifs in fungal glycome.					
36249563	1	27	theme	prokaryotic	184:194	arg1	glycomes					210:217	the prokaryotic and protistal glycomes	180:217	the prokaryotic and protistal glycomes	180:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	0	28	theme	fungal	48:53	arg1	glycome					55:61	fungal glycome	48:61	fungal glycome	48:61	Examining the diversity of structural motifs in fungal glycome.					
36249563	1	29	theme	Carbohydrate	282:293	arg1	CSDB					315:318	CSDB	315:318	CSDB	315:318	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	1	29	theme	Carbohydrate	282:293	arg1	Database					305:312	the Carbohydrate Structure Database	278:312	the Carbohydrate Structure Database (CSDB)	278:319	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	2	30	theme	net	474:476	arg1	charge					478:483	net charge	474:483	net charge	474:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	4	31	theme	fungal	826:831	arg1	species					833:839	a particular fungal species	813:839	a particular fungal species	813:839	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	1	32	theme	Structure	295:303	arg1	CSDB					315:318	CSDB	315:318	CSDB	315:318	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	1	32	theme	Structure	295:303	arg1	Database					305:312	the Carbohydrate Structure Database	278:312	the Carbohydrate Structure Database (CSDB)	278:319	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	3	33	theme	various	580:586	arg1	classes					595:601	various fungal classes	580:601	various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	580:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	1	34	from	comparison	164:173	arg1	analysis					130:137	a systematic statistical analysis	105:137	a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes	105:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	4	35	theme	specific	773:780	arg1	glycosyltransferases					782:801	specific glycosyltransferases	773:801	specific glycosyltransferases active in a particular fungal species	773:839	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	1	36	from	glycome	153:159	arg1	comparison					164:173	comparison	164:173	comparison with the prokaryotic and protistal glycomes	164:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	1	37	theme	protistal	200:208	arg1	glycomes					210:217	the prokaryotic and protistal glycomes	180:217	the prokaryotic and protistal glycomes	180:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	2	38	theme	charge	478:483	arg1	glycans					364:370	glycans	364:370	glycans	364:370	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	38	theme	charge	478:483	arg1	sizes					432:436	sizes	432:436	sizes of structures, branching degree and net charge	432:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	4	39	theme	active	803:808	arg1	glycosyltransferases					782:801	specific glycosyltransferases	773:801	specific glycosyltransferases active in a particular fungal species	773:839	It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.					
36249563	1	40	theme	systematic	107:116	arg1	analysis					130:137	a systematic statistical analysis	105:137	a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes	105:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	1	41	theme	fungal	146:151	arg1	glycome					153:159	the fungal glycome	142:159	the fungal glycome in comparison with the prokaryotic and protistal glycomes	142:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36249563	2	42	theme	structures	441:450	arg1	glycans					364:370	glycans	364:370	glycans	364:370	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	2	42	theme	structures	441:450	arg1	sizes					432:436	sizes	432:436	sizes of structures, branching degree and net charge	432:483	The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed.					
36249563	3	43	theme	tools	673:677	arg1	development					647:657	the development	643:657	the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi	643:734	The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi.					
36249563	1	44	theme	statistical	118:128	arg1	analysis					130:137	a systematic statistical analysis	105:137	a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes	105:217	In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB).					
36958184	4	0	theme	grass	880:884	arg1	slices					891:896	grass carp slices	880:896	grass carp slices	880:896	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	3	1	theme	barrier	506:512	arg1	property					514:521	break and light barrier property	490:521	property	514:521	The addition enhanced the elongation at break and light barrier property of the films.					
36958184	0	2	theme	inclusion	92:100	arg1	complex					102:108	inclusion complex	92:108	inclusion complex	92:108	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	5	3	theme	shelf	1070:1074	arg1	life					1076:1079	the shelf life	1066:1079	the shelf life of fish muscle	1066:1094	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	2	4	theme	inclusion	358:366	arg1	complex					368:374	its sulfobutyl ether-β-cyclodextrin inclusion complex	322:374	its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S)	322:381	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	4	theme	inclusion	358:366	arg1	CA/S					377:380	CA/S	377:380	CA/S	377:380	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	4	5	theme	slices	891:896	arg1	preservation					864:875	preservation	864:875	preservation of grass carp slices	864:896	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	3	6	from	property	514:521	arg1	elongation					476:485	the elongation	472:485	the elongation at break and light barrier property of the films	472:534	The addition enhanced the elongation at break and light barrier property of the films.					
36958184	6	7	theme	environmentally	1173:1187	arg1	friendly					1189:1196	environmentally friendly	1173:1196	environmentally friendly	1173:1196	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	4	8	theme	carp	886:889	arg1	slices					891:896	grass carp slices	880:896	grass carp slices	880:896	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	9	theme	packaging	755:763	arg1	solution					765:772	the packaging solution	751:772	the packaging solution of gelatin combined CA and CA/S	751:804	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	10	from	%	689:689	arg1	period					702:707	initial period	694:707	initial period	694:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	5	11	theme	fish	1084:1087	arg1	muscle					1089:1094	fish muscle	1084:1094	fish muscle	1084:1094	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	4	12	theme	microorganisms	842:855	arg1	growth					832:837	the growth	828:837	the growth of microorganisms	828:855	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	1	13	theme	higher	210:215	arg1	activity					231:238	higher antibacterial activity	210:238	higher antibacterial activity	210:238	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	3	14	theme	films	530:534	arg1	property					514:521	break and light barrier property	490:521	property	514:521	The addition enhanced the elongation at break and light barrier property of the films.					
36958184	1	15	theme	packaging	181:189	arg1	film					191:194	the packaging film	177:194	the packaging film	177:194	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	0	16	from	cinnamaldehyde	37:50	arg1	preservation					140:151	fish preservation	135:151	fish preservation	135:151	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	6	17	with	system	1143:1148	arg1	antimicrobial					1155:1167	antimicrobial	1155:1167	antimicrobial	1155:1167	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	6	17	with	system	1143:1148	arg1	friendly					1189:1196	environmentally friendly	1173:1196	environmentally friendly	1173:1196	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	0	18	theme	gelatin	5:11	arg1	films					13:17	Fish gelatin films	0:17	Fish gelatin films	0:17	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	0	19	theme	Fish	0:3	arg1	films					13:17	Fish gelatin films	0:17	Fish gelatin films	0:17	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	6	20	theme	packaging	1133:1141	arg1	system					1143:1148	a promising food packaging system	1116:1148	a promising food packaging system with antimicrobial and environmentally friendly	1116:1196	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	4	21	from	72 h.	736:740	arg1	ratio					629:633	the most excellent inhibition ratio	599:633	the most excellent inhibition ratio	599:633	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	21	from	72 h.	736:740	arg1	%					731:731	still 82.97 ± 4.55%	713:731	still 82.97 ± 4.55% at 72 h.	713:740	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	21	from	72 h.	736:740	arg1	%					689:689	98.43 ± 1.11%	677:689	98.43 ± 1.11% in initial period	677:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	0	22	dep	ether-β-cyclodextrin	71:90	arg1	complex					102:108	inclusion complex	92:108	inclusion complex	92:108	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	2	23	theme	antibacterial	419:431	arg1	films					443:447	fish gelatin antibacterial composite films	406:447	fish gelatin antibacterial composite films	406:447	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	24	theme	composite	433:441	arg1	films					443:447	fish gelatin antibacterial composite films	406:447	fish gelatin antibacterial composite films	406:447	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	0	25	theme	fish	135:138	arg1	preservation					140:151	fish preservation	135:151	fish preservation	135:151	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	6	26	theme	promising	1118:1126	arg1	system					1143:1148	a promising food packaging system	1116:1148	a promising food packaging system with antimicrobial and environmentally friendly	1116:1196	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	2	27	theme	gelatin	411:417	arg1	films					443:447	fish gelatin antibacterial composite films	406:447	fish gelatin antibacterial composite films	406:447	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	3	28	theme	light	500:504	arg1	property					514:521	break and light barrier property	490:521	property	514:521	The addition enhanced the elongation at break and light barrier property of the films.					
36958184	1	29	theme	antibacterial	217:229	arg1	activity					231:238	higher antibacterial activity	210:238	higher antibacterial activity	210:238	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	2	30	theme	fish	406:409	arg1	gelatin					411:417	fish gelatin	406:417	fish gelatin antibacterial composite films	406:447	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	4	31	theme	initial	694:700	arg1	period					702:707	initial period	694:707	initial period	694:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	0	32	from	ether-β-cyclodextrin	71:90	arg1	preservation					140:151	fish preservation	135:151	fish preservation	135:151	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	5	33	theme	volatile	921:928	arg1	TVB-N					951:955	TVB-N	951:955	TVB-N	951:955	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	5	33	theme	volatile	921:928	arg1	nitrogen					941:948	the total volatile salt-based nitrogen	911:948	the total volatile salt-based nitrogen (TVB-N)	911:956	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	5	34	theme	muscle	1089:1094	arg1	life					1076:1079	the shelf life	1066:1079	the shelf life of fish muscle	1066:1094	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	2	35	theme	ether-β-cyclodextrin	337:356	arg1	complex					368:374	its sulfobutyl ether-β-cyclodextrin inclusion complex	322:374	its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S)	322:381	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	35	theme	ether-β-cyclodextrin	337:356	arg1	CA/S					377:380	CA/S	377:380	CA/S	377:380	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	4	36	theme	forming	542:548	arg1	solution					550:557	Film forming solution	537:557	Film forming solution incorporated with CA and CA/S	537:587	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	5	37	theme	active	1028:1033	arg1	coating					1035:1041	the active coating	1024:1041	the active coating	1024:1041	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	6	38	theme	food	1128:1131	arg1	system					1143:1148	a promising food packaging system	1116:1148	a promising food packaging system with antimicrobial and environmentally friendly	1116:1196	This work provided a promising food packaging system with antimicrobial and environmentally friendly.					
36958184	2	39	theme	sulfobutyl	326:335	arg1	complex					368:374	its sulfobutyl ether-β-cyclodextrin inclusion complex	322:374	its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S)	322:381	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	39	theme	sulfobutyl	326:335	arg1	CA/S					377:380	CA/S	377:380	CA/S	377:380	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	4	40	theme	Film	537:540	arg1	solution					550:557	Film forming solution	537:557	Film forming solution incorporated with CA and CA/S	537:587	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	0	41	from	application	120:130	arg1	preservation					140:151	fish preservation	135:151	fish preservation	135:151	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	4	42	theme	CA	794:795	arg1	solution					765:772	the packaging solution	751:772	the packaging solution of gelatin combined CA and CA/S	751:804	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	5	43	theme	salt-based	930:939	arg1	TVB-N					951:955	TVB-N	951:955	TVB-N	951:955	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	5	43	theme	salt-based	930:939	arg1	nitrogen					941:948	the total volatile salt-based nitrogen	911:948	the total volatile salt-based nitrogen (TVB-N)	911:956	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	4	44	from	%	731:731	arg1	period					702:707	initial period	694:707	initial period	694:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	45	theme	excellent	608:616	arg1	%					689:689	98.43 ± 1.11%	677:689	98.43 ± 1.11% in initial period	677:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	45	theme	excellent	608:616	arg1	ratio					629:633	the most excellent inhibition ratio	599:633	the most excellent inhibition ratio	599:633	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	46	theme	gelatin	777:783	arg1	CA					794:795	gelatin combined CA	777:795	gelatin combined CA	777:795	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	5	47	theme	total	915:919	arg1	TVB-N					951:955	TVB-N	951:955	TVB-N	951:955	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	5	47	theme	total	915:919	arg1	nitrogen					941:948	the total volatile salt-based nitrogen	911:948	the total volatile salt-based nitrogen (TVB-N)	911:956	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	4	48	theme	combined	785:792	arg1	CA					794:795	gelatin combined CA	777:795	gelatin combined CA	777:795	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	3	49	theme	break	490:494	arg1	property					514:521	break and light barrier property	490:521	property	514:521	The addition enhanced the elongation at break and light barrier property of the films.					
36958184	1	50	theme	initial	243:249	arg1	phase					251:255	initial phase	243:255	initial phase	243:255	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	1	51	contain	have	205:208	arg2	activity					231:238	higher antibacterial activity	210:238	higher antibacterial activity	210:238	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	1	51	contain	have	205:208	arg1	film					191:194	the packaging film	177:194	the packaging film	177:194	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	4	52	theme	CA/S	801:804	arg1	solution					765:772	the packaging solution	751:772	the packaging solution of gelatin combined CA and CA/S	751:804	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	1	53	theme	food	158:161	arg1	preservation					163:174	food preservation	158:174	food preservation	158:174	For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity.					
36958184	0	54	theme	sulfobutyl	60:69	arg1	ether-β-cyclodextrin					71:90	its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation	56:151	ether-β-cyclodextrin	71:90	Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.					
36958184	5	55	theme	storage	999:1005	arg1	end					992:994	the end	988:994	the end of storage	988:1005	Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10 mg/100 g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle.					
36958184	2	56	used	used	388:391	arg2	CA/S					377:380	CA/S	377:380	CA/S	377:380	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	56	used	used	388:391	arg2	complex					368:374	its sulfobutyl ether-β-cyclodextrin inclusion complex	322:374	its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S)	322:381	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	56	used	used	388:391	arg2	CA					314:315	CA	314:315	CA	314:315	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	2	56	used	used	388:391	arg2	cinnamaldehyde					298:311	cinnamaldehyde	298:311	cinnamaldehyde (CA)	298:316	In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films.					
36958184	4	57	theme	inhibition	618:627	arg1	%					689:689	98.43 ± 1.11%	677:689	98.43 ± 1.11% in initial period	677:707	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36958184	4	57	theme	inhibition	618:627	arg1	ratio					629:633	the most excellent inhibition ratio	599:633	the most excellent inhibition ratio	599:633	Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43 ± 1.11% in initial period and still 82.97 ± 4.55% at 72 h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices.					
36649872	5	0	theme	PANI	1006:1009	arg1	effect					996:1001	The synergistic effect	980:1001	The synergistic effect of PANI and CNT	980:1017	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	5	1	dep	retardancy	1061:1070	arg1	HRR					1073:1075	HRR	1073:1075	HRR	1073:1075	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	5	1	dep	retardancy	1061:1070	arg1	HRC					1086:1088	HRC	1086:1088	HRC	1086:1088	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	5	1	dep	retardancy	1061:1070	arg1	THR					1078:1080	THR	1078:1080	THR	1078:1080	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	3	2	theme	in-situ	591:597	arg1	polymerization					599:612	in-situ polymerization	591:612	in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer	591:672	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	1	3	theme	multifunctional	320:334	arg1	materials					336:344	multifunctional materials	320:344	multifunctional materials	320:344	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	4	4	theme	shielding	913:921	arg1	value					934:938	shielding efficiency value	913:938	shielding efficiency value of 26 dB at the X band	913:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	6	5	theme	material	1311:1318	arg1	durability					1293:1302	the durability	1289:1302	the durability of the material	1289:1318	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	3	6	theme	delignified	628:638	arg1	wood					640:643	delignified wood	628:643	delignified wood	628:643	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	1	7	theme	electromagnetic	150:164	arg1	materials					176:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	1	8	theme	materials	336:344	arg1	sustainability					256:269	the sustainability	252:269	the sustainability of biomass	252:280	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	1	8	theme	materials	336:344	arg1	adaptability					304:315	the environmental adaptability	286:315	the environmental adaptability of multifunctional materials	286:344	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	3	9	from	polymerization	599:612	arg1	coating					649:655	coating	649:655	coating	649:655	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	3	9	from	polymerization	599:612	arg1	wood					640:643	delignified wood	628:643	delignified wood	628:643	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	10	theme	electromagnetic	874:888	arg1	performance					900:910	electromagnetic shielding performance	874:910	electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz))	874:977	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	3	11	dep	wood	640:643	arg1	layer					668:672	a PDMS/CNT layer	657:672	a PDMS/CNT layer	657:672	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	12	theme	PDMS/CNT/PANI	799:811	arg1	WA					813:814	the PDMS/CNT/PANI WA	795:814	the PDMS/CNT/PANI WA	795:814	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	2	13	theme	aligned	423:429	arg1	platform					458:465	a good platform	451:465	a good platform for building cellulose-based materials	451:504	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	2	13	theme	aligned	423:429	arg1	cellulose					431:439	aligned cellulose	423:439	aligned cellulose	423:439	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	1	14	from	interest	211:218	arg1	industry					236:243	industry	236:243	industry	236:243	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	1	14	from	interest	211:218	arg1	academia					223:230	academia	223:230	academia	223:230	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	3	15	theme	aniline	617:623	arg1	polymerization					599:612	in-situ polymerization	591:612	in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer	591:672	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	16	theme	continuous	764:773	arg1	network					786:792	the constructed multilayer continuous conductive network	737:792	the constructed multilayer continuous conductive network	737:792	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	7	17	theme	new	1342:1344	arg1	strategy					1346:1353	a new strategy	1340:1353	a new strategy for developing sustainable and multifunctional electromagnetic shielding materials	1340:1436	This work provides a new strategy for developing sustainable and multifunctional electromagnetic shielding materials.					
36649872	4	18	theme	multilayer	753:762	arg1	network					786:792	the constructed multilayer continuous conductive network	737:792	the constructed multilayer continuous conductive network	737:792	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	4	19	from	band	958:961	arg1	value					934:938	shielding efficiency value	913:938	shielding efficiency value of 26 dB at the X band	913:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	6	20	theme	105°	1216:1219	arg1	angle					1207:1211	a water contact angle	1191:1211	a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material	1191:1318	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	4	21	dep	performance	900:910	arg1	value					934:938	shielding efficiency value	913:938	shielding efficiency value of 26 dB at the X band	913:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	2	22	theme	good	453:456	arg1	platform					458:465	a good platform	451:465	a good platform for building cellulose-based materials	451:504	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	2	22	theme	good	453:456	arg1	cellulose					431:439	aligned cellulose	423:439	aligned cellulose	423:439	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	4	23	theme	electrical	835:844	arg1	18.6 S/m					860:867	18.6 S/m	860:867	18.6 S/m	860:867	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	4	23	theme	electrical	835:844	arg1	conductivity					846:857	excellent electrical conductivity	825:857	excellent electrical conductivity (18.6 S/m)	825:868	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	24	theme	Biomass-based	120:132	arg1	materials					176:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	4	25	theme	conductive	775:784	arg1	network					786:792	the constructed multilayer continuous conductive network	737:792	the constructed multilayer continuous conductive network	737:792	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	26	theme	multifunctional	134:148	arg1	materials					176:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	0	27	theme	multifunctional	28:42	arg1	material					44:51	multifunctional material	28:51	multifunctional material for electromagnetic shielding, flame retardancy and antibacterial	28:117	Sustainable cellulose-based multifunctional material for electromagnetic shielding, flame retardancy and antibacterial.					
36649872	5	28	theme	excellent	1045:1053	arg1	retardancy					1061:1070	excellent flame retardancy	1045:1070	excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %)	1045:1126	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	2	29	with	substrate	408:416	arg1	platform					458:465	a good platform	451:465	a good platform for building cellulose-based materials	451:504	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	2	29	with	substrate	408:416	arg1	cellulose					431:439	aligned cellulose	423:439	aligned cellulose	423:439	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	2	30	theme	hemicellulose	373:385	arg1	wood					387:390	hemicellulose wood	373:390	hemicellulose wood	373:390	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	7	31	theme	shielding	1418:1426	arg1	materials					1428:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	This work provides a new strategy for developing sustainable and multifunctional electromagnetic shielding materials.					
36649872	0	32	theme	electromagnetic	57:71	arg1	shielding					73:81	electromagnetic shielding	57:81	electromagnetic shielding	57:81	Sustainable cellulose-based multifunctional material for electromagnetic shielding, flame retardancy and antibacterial.					
36649872	3	33	with	composite	533:541	arg1	structure					562:570	sandwich-like structure	548:570	sandwich-like structure	548:570	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	34	theme	constructed	741:751	arg1	network					786:792	the constructed multilayer continuous conductive network	737:792	the constructed multilayer continuous conductive network	737:792	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	5	35	theme	synergistic	984:994	arg1	effect					996:1001	The synergistic effect	980:1001	The synergistic effect of PANI and CNT	980:1017	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	2	36	theme	cellulose-based	480:494	arg1	materials					496:504	cellulose-based materials	480:504	cellulose-based materials	480:504	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	5	37	theme	significant	1132:1142	arg1	activity					1158:1165	significant antibacterial activity	1132:1165	significant antibacterial activity	1132:1165	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	4	38	theme	26 dB	943:947	arg1	value					934:938	shielding efficiency value	913:938	shielding efficiency value of 26 dB at the X band	913:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	39	theme	biomass	274:280	arg1	sustainability					256:269	the sustainability	252:269	the sustainability of biomass	252:280	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	1	39	theme	biomass	274:280	arg1	adaptability					304:315	the environmental adaptability	286:315	the environmental adaptability of multifunctional materials	286:344	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	5	40	theme	antibacterial	1144:1156	arg1	activity					1158:1165	significant antibacterial activity	1132:1165	significant antibacterial activity	1132:1165	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	4	41	theme	X	956:956	arg1	band					958:961	the X band	952:961	the X band	952:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	42	theme	shielding	166:174	arg1	materials					176:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials	120:184	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	5	43	with	endowed	1019:1025	arg1	activity					1158:1165	significant antibacterial activity	1132:1165	significant antibacterial activity	1132:1165	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	5	43	with	endowed	1019:1025	arg1	retardancy					1061:1070	excellent flame retardancy	1045:1070	excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %)	1045:1126	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	6	44	theme	protective	1254:1263	arg1	layer					1265:1269	a protective layer	1252:1269	a protective layer	1252:1269	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	6	44	theme	protective	1254:1263	arg1	material					1228:1235	the material	1224:1235	the material	1224:1235	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	7	45	theme	sustainable	1370:1380	arg1	materials					1428:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	This work provides a new strategy for developing sustainable and multifunctional electromagnetic shielding materials.					
36649872	4	46	theme	excellent	825:833	arg1	18.6 S/m					860:867	18.6 S/m	860:867	18.6 S/m	860:867	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	4	46	theme	excellent	825:833	arg1	conductivity					846:857	excellent electrical conductivity	825:857	excellent electrical conductivity (18.6 S/m)	825:868	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	7	47	theme	electromagnetic	1402:1416	arg1	materials					1428:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	This work provides a new strategy for developing sustainable and multifunctional electromagnetic shielding materials.					
36649872	4	48	theme	efficiency	923:932	arg1	value					934:938	shielding efficiency value	913:938	shielding efficiency value of 26 dB at the X band	913:961	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	3	49	theme	sandwich-like	548:560	arg1	structure					562:570	sandwich-like structure	548:570	sandwich-like structure	548:570	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	5	50	theme	flame	1055:1059	arg1	retardancy					1061:1070	excellent flame retardancy	1045:1070	excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %)	1045:1126	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	4	51	theme	natural	695:701	arg1	structure					723:731	the natural porous hierarchical structure	691:731	the natural porous hierarchical structure	691:731	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	5	52	theme	CNT	1015:1017	arg1	effect					996:1001	The synergistic effect	980:1001	The synergistic effect of PANI and CNT	980:1017	The synergistic effect of PANI and CNT endowed the material with excellent flame retardancy (HRR, THR and HRC decreased by 84 %, 53.4 % and 83.3 %) and significant antibacterial activity.					
36649872	4	53	theme	shielding	890:898	arg1	performance					900:910	electromagnetic shielding performance	874:910	electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz))	874:977	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	2	54	theme	porous	401:406	arg1	substrate					408:416	a porous substrate	399:416	a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials	399:504	After removing lignin and hemicellulose wood become a porous substrate with aligned cellulose, which is a good platform for building cellulose-based materials.					
36649872	6	55	theme	water	1193:1197	arg1	angle					1207:1211	a water contact angle	1191:1211	a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material	1191:1318	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	3	56	theme	cellulose	523:531	arg1	composite					533:541	a cellulose composite	521:541	a cellulose composite with sandwich-like structure	521:570	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	57	theme	hierarchical	710:721	arg1	structure					723:731	the natural porous hierarchical structure	691:731	the natural porous hierarchical structure	691:731	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	58	theme	extensive	201:209	arg1	interest					211:218	extensive interest	201:218	extensive interest in academia and industry	201:243	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	4	59	dep	value	934:938	arg1	8.2-12.4 GHz					964:975	8.2-12.4 GHz	964:975	8.2-12.4 GHz	964:975	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
36649872	1	60	theme	environmental	290:302	arg1	adaptability					304:315	the environmental adaptability	286:315	the environmental adaptability of multifunctional materials	286:344	Biomass-based multifunctional electromagnetic shielding materials have attracted extensive interest in academia and industry due to the sustainability of biomass and the environmental adaptability of multifunctional materials.					
36649872	0	61	theme	flame	84:88	arg1	retardancy					90:99	flame retardancy	84:99	flame retardancy	84:99	Sustainable cellulose-based multifunctional material for electromagnetic shielding, flame retardancy and antibacterial.					
36649872	6	62	theme	contact	1199:1205	arg1	angle					1207:1211	a water contact angle	1191:1211	a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material	1191:1318	Moreover, PDMS imparts a water contact angle of 105° to the material, which acts as a protective layer, further improves the durability of the material.					
36649872	7	63	theme	multifunctional	1386:1400	arg1	materials					1428:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	sustainable and multifunctional electromagnetic shielding materials	1370:1436	This work provides a new strategy for developing sustainable and multifunctional electromagnetic shielding materials.					
36649872	3	64	theme	PDMS/CNT	659:666	arg1	layer					668:672	a PDMS/CNT layer	657:672	a PDMS/CNT layer	657:672	In this work, a cellulose composite with sandwich-like structure was constructed by in-situ polymerization of aniline on delignified wood and coating a PDMS/CNT layer.					
36649872	4	65	theme	porous	703:708	arg1	structure					723:731	the natural porous hierarchical structure	691:731	the natural porous hierarchical structure	691:731	Benefiting from the natural porous hierarchical structure and the constructed multilayer continuous conductive network, the PDMS/CNT/PANI WA exhibits excellent electrical conductivity (18.6 S/m) and electromagnetic shielding performance (shielding efficiency value of 26 dB at the X band (8.2-12.4 GHz)).					
37194686	9	0	contain	has	1270:1272	arg1	CAPs-SF/MC					1259:1268	CAPs-SF/MC	1259:1268	CAPs-SF/MC	1259:1268	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	9	0	contain	has	1270:1272	arg2	biocompatibility					1279:1294	good biocompatibility	1274:1294	good biocompatibility with less cytotoxicity	1274:1317	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	7	1	contain	have	1044:1047	arg2	size					1059:1062	a smaller size	1049:1062	a smaller size	1049:1062	The CAPs in CAPs-SF/MC have a smaller size than those in CAPs-MC.					
37194686	7	1	contain	have	1044:1047	arg1	CAPs					1025:1028	The CAPs	1021:1028	The CAPs in CAPs-SF/MC	1021:1042	The CAPs in CAPs-SF/MC have a smaller size than those in CAPs-MC.					
37194686	9	2	theme	mouse	1349:1353	arg1	line					1374:1377	mouse preosteoblast cell line	1349:1377	mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC	1349:1413	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	9	2	theme	mouse	1349:1353	arg1	MC3T3-E1					1380:1387	MC3T3-E1	1380:1387	MC3T3-E1	1380:1387	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	11	3	theme	clinical	1648:1655	arg1	advantages					1657:1666	clinical advantages	1648:1666	clinical advantages	1648:1666	In conclusion SF incorporated into composite injectable hydrogel potentially improve biological characteristics and may provide clinical advantages.					
37194686	7	4	from	CAPs	1025:1028	arg1	CAPs-SF/MC					1033:1042	CAPs-SF/MC	1033:1042	CAPs-SF/MC	1033:1042	The CAPs in CAPs-SF/MC have a smaller size than those in CAPs-MC.					
37194686	4	5	theme	only	615:618	arg1	CAPs-MC					637:643	CAPs-MC	637:643	CAPs-MC	637:643	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	4	5	theme	only	615:618	arg1	methylcellulose					620:634	only methylcellulose	615:634	only methylcellulose (CAPs-MC)	615:644	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	4	6	theme	phosphate	533:541	arg1	particles					543:551	the calcium phosphate particles	521:551	the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels	521:654	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	10	7	theme	better	1447:1452	arg1	possibility					1454:1464	better possibility	1447:1464	better possibility	1447:1464	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	0	8	dep	in	125:126	arg1	vitro					128:132	vitro	128:132	vitro	128:132	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	11	9	theme	biological	1605:1614	arg1	characteristics					1616:1630	biological characteristics	1605:1630	biological characteristics	1605:1630	In conclusion SF incorporated into composite injectable hydrogel potentially improve biological characteristics and may provide clinical advantages.					
37194686	9	10	theme	cell	1369:1372	arg1	line					1374:1377	mouse preosteoblast cell line	1349:1377	mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC	1349:1413	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	9	10	theme	cell	1369:1372	arg1	MC3T3-E1					1380:1387	MC3T3-E1	1380:1387	MC3T3-E1	1380:1387	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	5	11	theme	CAPs-hydrogels	722:735	arg1	solutions					737:745	Both CAPs-hydrogels solutions	717:745	Both CAPs-hydrogels solutions	717:745	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	0	12	theme	in	125:126	arg1	evaluation					145:154	in vitro biological evaluation	125:154	in vitro biological evaluation	125:154	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	6	13	theme	hydrogel	938:945	arg1	matrix					947:952	the hydrogel matrix	934:952	the hydrogel matrix	934:952	The CAPs are evenly distributed throughout the hydrogel matrix and are capable transformed to bioactive hydroxyapatite at pH 7.4.					
37194686	8	14	theme	greater	1218:1224	arg1	ability					1226:1232	a greater ability	1216:1232	a greater ability to sustain CAPs release	1216:1256	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	3	15	theme	biodegradable	489:501	arg1	properties					503:512	its biocompatible and biodegradable properties	467:512	its biocompatible and biodegradable properties	467:512	Herein, silk fibroin (SF) is noticeable polymer regarding its biocompatible and biodegradable properties.					
37194686	2	16	theme	different	292:300	arg1	geometry					302:309	different geometry	292:309	different geometry of bone defect	292:324	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	1	17	theme	Bone	183:186	arg1	problem					218:224	a challenging problem	204:224	a challenging problem in orthopedic practice	204:247	Bone defect is still a challenging problem in orthopedic practice.					
37194686	1	17	theme	Bone	183:186	arg1	defect					188:193	Bone defect	183:193	Bone defect	183:193	Bone defect is still a challenging problem in orthopedic practice.					
37194686	0	18	theme	Calcium	0:6	arg1	phosphate					8:16	Calcium phosphate	0:16	Calcium phosphate incorporated in silk fibroin/methylcellulose	0:61	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	5	19	theme	~6 N	801:804	arg1	force					792:796	a low injectability force	772:796	a low injectability force of ~6 N	772:804	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	8	20	theme	Peppas-Sahlin	1187:1199	arg1	model					1201:1205	the Peppas-Sahlin model	1183:1205	the Peppas-Sahlin model	1183:1205	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	8	21	theme	gradual	1116:1122	arg1	degradation					1124:1134	gradual degradation	1116:1134	gradual degradation	1116:1134	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	11	22	theme	injectable	1565:1574	arg1	hydrogel					1576:1583	composite injectable hydrogel	1555:1583	composite injectable hydrogel	1555:1583	In conclusion SF incorporated into composite injectable hydrogel potentially improve biological characteristics and may provide clinical advantages.					
37194686	3	23	theme	silk	417:420	arg1	SF					431:432	SF	431:432	SF	431:432	Herein, silk fibroin (SF) is noticeable polymer regarding its biocompatible and biodegradable properties.					
37194686	3	23	theme	silk	417:420	arg1	fibroin					422:428	silk fibroin	417:428	silk fibroin (SF)	417:433	Herein, silk fibroin (SF) is noticeable polymer regarding its biocompatible and biodegradable properties.					
37194686	3	24	theme	noticeable	438:447	arg1	polymer					449:455	noticeable polymer	438:455	noticeable polymer regarding its biocompatible and biodegradable properties	438:512	Herein, silk fibroin (SF) is noticeable polymer regarding its biocompatible and biodegradable properties.					
37194686	8	25	theme	CAPs	1245:1248	arg1	release					1250:1256	CAPs release	1245:1256	CAPs release	1245:1256	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	5	26	theme	physiological	857:869	arg1	37°C					884:887	37°C	884:887	37°C	884:887	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	5	26	theme	physiological	857:869	arg1	temperature					871:881	physiological temperature	857:881	physiological temperature (37°C)	857:888	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	0	27	theme	biological	134:143	arg1	evaluation					145:154	in vitro biological evaluation	125:154	in vitro biological evaluation	125:154	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	2	28	theme	defect	319:324	arg1	geometry					302:309	different geometry	292:309	different geometry of bone defect	292:324	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	6	29	from	pH 7.4	1013:1018	arg1	hydroxyapatite					995:1008	bioactive hydroxyapatite	985:1008	bioactive hydroxyapatite at pH 7.4	985:1018	The CAPs are evenly distributed throughout the hydrogel matrix and are capable transformed to bioactive hydroxyapatite at pH 7.4.					
37194686	9	30	theme	good	1274:1277	arg1	biocompatibility					1279:1294	good biocompatibility	1274:1294	good biocompatibility with less cytotoxicity	1274:1317	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	2	31	theme	bone	314:317	arg1	defect					319:324	bone defect	314:324	bone defect	314:324	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	1	32	theme	challenging	206:216	arg1	problem					218:224	a challenging problem	204:224	a challenging problem in orthopedic practice	204:247	Bone defect is still a challenging problem in orthopedic practice.					
37194686	1	32	theme	challenging	206:216	arg1	defect					188:193	Bone defect	183:193	Bone defect	183:193	Bone defect is still a challenging problem in orthopedic practice.					
37194686	5	33	theme	low	774:776	arg1	force					792:796	a low injectability force	772:796	a low injectability force of ~6 N	772:804	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	2	34	theme	Injectable	250:259	arg1	bone					261:264	Injectable bone	250:264	Injectable bone	250:264	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	9	35	with	biocompatibility	1279:1294	arg1	cytotoxicity					1306:1317	less cytotoxicity	1301:1317	less cytotoxicity	1301:1317	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	4	36	theme	physicochemical	689:703	arg1	properties					705:714	their physicochemical properties	683:714	their physicochemical properties	683:714	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	0	37	theme	silk	34:37	arg1	fibroin/methylcellulose					39:61	silk fibroin/methylcellulose	34:61	silk fibroin/methylcellulose	34:61	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	5	38	theme	injectability	778:790	arg1	force					792:796	a low injectability force	772:796	a low injectability force of ~6 N	772:804	Both CAPs-hydrogels solutions can be administered with a low injectability force of ~6 N, and they require ~40-min to change to hydrogel at physiological temperature (37°C).					
37194686	1	39	from	problem	218:224	arg1	practice					240:247	orthopedic practice	229:247	orthopedic practice	229:247	Bone defect is still a challenging problem in orthopedic practice.					
37194686	3	40	theme	biocompatible	471:483	arg1	properties					503:512	its biocompatible and biodegradable properties	467:512	its biocompatible and biodegradable properties	467:512	Herein, silk fibroin (SF) is noticeable polymer regarding its biocompatible and biodegradable properties.					
37194686	0	41	theme	injectable	69:78	arg1	Preparation					90:100	injectable hydrogel: Preparation	69:100	injectable hydrogel: Preparation	69:100	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	0	42	theme	defect	165:170	arg1	treatment					172:180	bone defect treatment	160:180	bone defect treatment	160:180	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	9	43	theme	less	1301:1304	arg1	cytotoxicity					1306:1317	less cytotoxicity	1301:1317	less cytotoxicity	1301:1317	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	2	44	theme	bone	365:368	arg1	regeneration					370:381	bone regeneration	365:381	bone regeneration	365:381	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	9	45	theme	preosteoblast	1355:1367	arg1	line					1374:1377	mouse preosteoblast cell line	1349:1377	mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC	1349:1413	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	9	45	theme	preosteoblast	1355:1367	arg1	MC3T3-E1					1380:1387	MC3T3-E1	1380:1387	MC3T3-E1	1380:1387	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	6	46	theme	bioactive	985:993	arg1	hydroxyapatite					995:1008	bioactive hydroxyapatite	985:1008	bioactive hydroxyapatite at pH 7.4	985:1018	The CAPs are evenly distributed throughout the hydrogel matrix and are capable transformed to bioactive hydroxyapatite at pH 7.4.					
37194686	0	47	theme	bone	160:163	arg1	treatment					172:180	bone defect treatment	160:180	bone defect treatment	160:180	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	7	48	theme	smaller	1051:1057	arg1	size					1059:1062	a smaller size	1049:1062	a smaller size	1049:1062	The CAPs in CAPs-SF/MC have a smaller size than those in CAPs-MC.					
37194686	4	49	theme	silk	569:572	arg1	CAPs-SF/MC					599:608	CAPs-SF/MC	599:608	CAPs-SF/MC	599:608	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	4	49	theme	silk	569:572	arg1	fibroin/methylcellulose					574:596	silk fibroin/methylcellulose	569:596	silk fibroin/methylcellulose (CAPs-SF/MC)	569:609	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	8	50	theme	mechanism	1170:1178	arg1	prediction					1140:1149	prediction	1140:1149	prediction of the degradation mechanism by the Peppas-Sahlin model	1140:1205	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	4	51	dep	fibroin/methylcellulose	574:596	arg1	hydrogels					646:654	hydrogels	646:654	hydrogels	646:654	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
37194686	1	52	theme	orthopedic	229:238	arg1	practice					240:247	orthopedic practice	229:247	orthopedic practice	229:247	Bone defect is still a challenging problem in orthopedic practice.					
37194686	8	53	theme	degradation	1158:1168	arg1	mechanism					1170:1178	the degradation mechanism	1154:1178	the degradation mechanism by the Peppas-Sahlin model	1154:1205	Moreover, CAPs-SF/MC exhibit gradual degradation, as prediction of the degradation mechanism by the Peppas-Sahlin model and show a greater ability to sustain CAPs release.					
37194686	2	54	theme	biological	338:347	arg1	environment					349:359	biological environment for bone regeneration are attracting attention	338:406	biological environment for bone regeneration are attracting attention	338:406	Injectable bone substitutes that can fill different geometry of bone defect and improve biological environment for bone regeneration are attracting attention.					
37194686	11	55	theme	composite	1555:1563	arg1	hydrogel					1576:1583	composite injectable hydrogel	1555:1583	composite injectable hydrogel	1555:1583	In conclusion SF incorporated into composite injectable hydrogel potentially improve biological characteristics and may provide clinical advantages.					
37194686	10	56	contain	have	1442:1445	arg2	possibility					1454:1464	better possibility	1447:1464	better possibility	1447:1464	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	10	56	contain	have	1442:1445	arg1	hydrogels					1427:1435	CAPs-SF/MC hydrogels	1416:1435	CAPs-SF/MC hydrogels	1416:1435	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	9	57	theme	dose-dependent	1324:1337	arg1	manner					1339:1344	a dose-dependent manner	1322:1344	a dose-dependent manner	1322:1344	CAPs-SF/MC has good biocompatibility with less cytotoxicity in a dose-dependent manner on mouse preosteoblast cell line (MC3T3-E1) when compared to CAPs-MC.					
37194686	10	58	theme	CAPs-SF/MC	1416:1425	arg1	hydrogels					1427:1435	CAPs-SF/MC hydrogels	1416:1435	CAPs-SF/MC hydrogels	1416:1435	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	10	59	dep	cell	1480:1483	arg1	differentiation					1503:1517	differentiation	1503:1517	differentiation	1503:1517	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	10	59	dep	cell	1480:1483	arg1	proliferation					1485:1497	proliferation	1485:1497	proliferation	1485:1497	CAPs-SF/MC hydrogels also have better possibility for promoting cell proliferation and differentiation.					
37194686	0	60	theme	hydrogel	80:87	arg1	Preparation					90:100	injectable hydrogel: Preparation	69:100	injectable hydrogel: Preparation	69:100	Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment.					
37194686	4	61	theme	calcium	525:531	arg1	phosphate					533:541	calcium phosphate	525:541	the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels	521:654	Thus, the calcium phosphate particles incorporated in silk fibroin/methylcellulose (CAPs-SF/MC) and only methylcellulose (CAPs-MC) hydrogels are developed and compared their physicochemical properties.					
36088022	4	0	theme	hemostatic	657:666	arg1	effects					668:674	better hemostatic effects	650:674	better hemostatic effects	650:674	Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges.					
36088022	1	1	with	dressings	157:165	arg1	functions					172:180	functions	172:180	functions	172:180	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	1	1	with	dressings	157:165	arg1	healing					237:243	wound healing	231:243	wound healing	231:243	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	1	1	with	dressings	157:165	arg1	hemostasis					191:200	hemostasis	191:200	hemostasis	191:200	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	1	1	with	dressings	157:165	arg1	activity					217:224	antibacterial activity	203:224	antibacterial activity	203:224	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	6	2	theme	antioxidant	870:880	arg1	AuNPs					882:886	antioxidant AuNPs	870:886	antioxidant AuNPs	870:886	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	1	3	theme	dressings	157:165	arg1	development					122:132	The development	118:132	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing,	118:244	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	0	4	theme	shape	74:78	arg1	recovery					80:87	shape recovery	74:87	shape recovery	74:87	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	6	5	theme	faster	914:919	arg1	rate					935:938	a significantly faster wound healing rate	898:938	a significantly faster wound healing rate (reaching 41.6 % on day 3)	898:965	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	2	6	theme	stalk/chitin	324:335	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	6	theme	stalk/chitin	324:335	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	6	7	theme	cell	1033:1036	arg1	migration					1038:1046	cell migration	1033:1046	cell migration	1033:1046	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	6	8	theme	control	992:998	arg1	group					1009:1013	the CH (33.2 %) and control (12.6 %) group	972:1013	group	1009:1013	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	6	8	theme	control	992:998	arg1	%					1006:1006	12.6 %	1001:1006	12.6 %	1001:1006	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	5	9	theme	photothermal	709:720	arg1	effect					722:727	The photothermal effect	705:727	The photothermal effect of AuNPs	705:736	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	3	10	theme	porous	505:510	arg1	ability					541:547	the porous chitin sponge shape-recovery ability	501:547	the porous chitin sponge shape-recovery ability	501:547	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	2	11	theme	composite	337:345	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	11	theme	composite	337:345	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	1	12	theme	great	252:256	arg1	significance					258:269	great significance	252:269	great significance	252:269	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	5	13	theme	composite	750:758	arg1	sponge					760:765	the composite sponge	746:765	the composite sponge	746:765	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	4	14	theme	PVF	692:694	arg1	sponges					696:702	commercial PVF sponges	681:702	commercial PVF sponges	681:702	Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges.					
36088022	7	15	theme	composite	1118:1126	arg1	sponge					1128:1133	the multifunctional composite sponge	1098:1133	the multifunctional composite sponge with great biocompatibility in this work	1098:1174	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	0	16	with	sponge	62:67	arg1	recovery					80:87	shape recovery	74:87	shape recovery	74:87	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	3	17	theme	stalk	490:494	arg1	addition					467:474	The addition	463:474	The addition of AuNPs@corn stalk	463:494	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	4	18	theme	composite	626:634	arg1	sponge					636:641	the composite sponge	622:641	the composite sponge	622:641	Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges.					
36088022	0	19	theme	wound	103:107	arg1	healing					109:115	wound healing	103:115	wound healing	103:115	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	7	20	from	sponge	1128:1133	arg1	work					1171:1174	this work	1166:1174	this work	1166:1174	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	2	21	theme	stalk-embedded	420:433	arg1	nanoparticles					440:452	corn stalk-embedded gold nanoparticles	415:452	corn stalk-embedded gold nanoparticles (AuNPs)	415:460	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	21	theme	stalk-embedded	420:433	arg1	AuNPs					455:459	AuNPs	455:459	AuNPs	455:459	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	7	22	theme	great	1140:1144	arg1	biocompatibility					1146:1161	great biocompatibility	1140:1161	great biocompatibility	1140:1161	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	0	23	theme	antibacterial	3:15	arg1	corn					34:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	3	24	theme	corn	485:488	arg1	stalk					490:494	AuNPs@corn stalk	479:494	AuNPs@corn stalk	479:494	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	1	25	from	significance	258:269	arg1	applications					283:294	clinical applications	274:294	clinical applications	274:294	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	3	26	theme	shape-recovery	526:539	arg1	ability					541:547	the porous chitin sponge shape-recovery ability	501:547	the porous chitin sponge shape-recovery ability	501:547	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	2	27	theme	corn	415:418	arg1	nanoparticles					440:452	corn stalk-embedded gold nanoparticles	415:452	corn stalk-embedded gold nanoparticles (AuNPs)	415:460	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	27	theme	corn	415:418	arg1	AuNPs					455:459	AuNPs	455:459	AuNPs	455:459	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	6	28	dep	rate	935:938	arg1	reaching					941:948	reaching	941:948	reaching 41.6 % on day 3	941:964	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	0	29	theme	AuNPs	28:32	arg1	corn					34:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	7	30	theme	wound	1210:1214	arg1	healing					1216:1222	wound healing	1210:1222	wound healing	1210:1222	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	3	31	theme	chitin	512:517	arg1	ability					541:547	the porous chitin sponge shape-recovery ability	501:547	the porous chitin sponge shape-recovery ability	501:547	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	2	32	theme	chitin	396:401	arg1	matrix					403:408	the chitin matrix	392:408	the chitin matrix	392:408	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	0	33	theme	hemostatic	17:26	arg1	corn					34:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	1	34	theme	clinical	274:281	arg1	applications					283:294	clinical applications	274:294	clinical applications	274:294	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	3	35	theme	sponge	519:524	arg1	ability					541:547	the porous chitin sponge shape-recovery ability	501:547	the porous chitin sponge shape-recovery ability	501:547	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	6	36	theme	wound	921:925	arg1	rate					935:938	a significantly faster wound healing rate	898:938	a significantly faster wound healing rate (reaching 41.6 % on day 3)	898:965	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	3	37	theme	@	484:484	arg1	stalk					490:494	AuNPs@corn stalk	479:494	AuNPs@corn stalk	479:494	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	4	38	theme	commercial	681:690	arg1	sponges					696:702	commercial PVF sponges	681:702	commercial PVF sponges	681:702	Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges.					
36088022	6	39	theme	collagen	1066:1073	arg1	deposition					1075:1084	collagen deposition	1066:1084	collagen deposition	1066:1084	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	1	40	theme	antibacterial	203:215	arg1	activity					217:224	antibacterial activity	203:224	antibacterial activity	203:224	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	0	41	theme	@	33:33	arg1	corn					34:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn	0:37	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	6	42	theme	composite	842:850	arg1	sponge					852:857	composite sponge	842:857	composite sponge containing antioxidant AuNPs	842:886	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	7	43	theme	multifunctional	1102:1116	arg1	sponge					1128:1133	the multifunctional composite sponge	1098:1133	the multifunctional composite sponge with great biocompatibility in this work	1098:1174	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	6	44	contain	containing	859:868	arg1	sponge					852:857	composite sponge	842:857	composite sponge containing antioxidant AuNPs	842:886	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	6	44	contain	containing	859:868	arg2	AuNPs					882:886	antioxidant AuNPs	870:886	antioxidant AuNPs	870:886	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	0	45	theme	composite	52:60	arg1	sponge					62:67	composite sponge	52:67	composite sponge with shape recovery for promoting wound healing	52:115	An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing.					
36088022	5	46	theme	antibacterial	782:794	arg1	activity					796:803	excellent antibacterial activity	772:803	excellent antibacterial activity	772:803	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	7	47	theme	potential	1187:1195	arg1	strategy					1197:1204	a potential strategy	1185:1204	a potential strategy for wound healing	1185:1222	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	2	48	theme	corn	319:322	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	48	theme	corn	319:322	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	49	theme	gold	435:438	arg1	nanoparticles					440:452	corn stalk-embedded gold nanoparticles	415:452	corn stalk-embedded gold nanoparticles (AuNPs)	415:460	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	49	theme	gold	435:438	arg1	AuNPs					455:459	AuNPs	455:459	AuNPs	455:459	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	3	50	theme	improved	554:561	arg1	softness					563:570	improved softness	554:570	improved softness	554:570	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	3	51	theme	AuNPs	479:483	arg1	stalk					490:494	AuNPs@corn stalk	479:494	AuNPs@corn stalk	479:494	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	2	52	theme	@	318:318	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	52	theme	@	318:318	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	4	53	theme	better	650:655	arg1	effects					668:674	better hemostatic effects	650:674	better hemostatic effects	650:674	Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges.					
36088022	2	54	theme	AuNPs	313:317	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	54	theme	AuNPs	313:317	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	7	55	with	sponge	1128:1133	arg1	biocompatibility					1146:1161	great biocompatibility	1140:1161	great biocompatibility	1140:1161	Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing.					
36088022	3	56	theme	water	587:591	arg1	absorption					593:602	water absorption	587:602	water absorption	587:602	The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption.					
36088022	2	57	theme	novel	307:311	arg1	CCAu					355:358	CCAu	355:358	CCAu	355:358	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	2	57	theme	novel	307:311	arg1	sponge					347:352	a novel AuNPs@corn stalk/chitin composite sponge	305:352	a novel AuNPs@corn stalk/chitin composite sponge (CCAu)	305:359	Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs).					
36088022	5	58	theme	AuNPs	732:736	arg1	effect					722:727	The photothermal effect	705:727	The photothermal effect of AuNPs	705:736	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	1	59	theme	shape-memory	137:148	arg1	dressings					157:165	shape-memory sponge dressings	137:165	shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing,	137:244	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	1	60	theme	wound	231:235	arg1	healing					237:243	wound healing	231:243	wound healing	231:243	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36088022	5	61	theme	excellent	772:780	arg1	activity					796:803	excellent antibacterial activity	772:803	excellent antibacterial activity	772:803	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	6	62	theme	healing	927:933	arg1	rate					935:938	a significantly faster wound healing rate	898:938	a significantly faster wound healing rate (reaching 41.6 % on day 3)	898:965	In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition.					
36088022	5	63	with	endowed	738:744	arg1	activity					796:803	excellent antibacterial activity	772:803	excellent antibacterial activity	772:803	The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity.					
36088022	1	64	theme	sponge	150:155	arg1	dressings					157:165	shape-memory sponge dressings	137:165	shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing,	137:244	The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications.					
36264640	6	0	theme	large	898:902	arg1	area					921:924	a large specific surface area	896:924	a large specific surface area	896:924	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	6	1	theme	carbon	859:864	arg1	content					866:872	a high carbon content	852:872	a high carbon content	852:872	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	6	1	theme	carbon	859:864	arg1	porosity					882:889	a high porosity	875:889	a high porosity	875:889	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	3	2	theme	chemical	447:454	arg1	structure					468:476	chemical and crystal structure	447:476	structure	468:476	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	7	3	from	application	1173:1183	arg1	photocatalysis					1213:1226	photocatalysis	1213:1226	photocatalysis	1213:1226	It is believed that this study would provide an effective approach to preparing a photocatalyst and broaden the potential application of cellulose nanofibrils in photocatalysis.					
36264640	6	4	theme	high	854:857	arg1	content					866:872	a high carbon content	852:872	a high carbon content	852:872	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	6	4	theme	high	854:857	arg1	porosity					882:889	a high porosity	875:889	a high porosity	875:889	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	7	5	theme	potential	1163:1171	arg1	application					1173:1183	the potential application	1159:1183	the potential application of cellulose nanofibrils in photocatalysis	1159:1226	It is believed that this study would provide an effective approach to preparing a photocatalyst and broaden the potential application of cellulose nanofibrils in photocatalysis.					
36264640	3	6	theme	composition	434:444	arg1	terms					412:416	terms	412:416	terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties	412:525	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	6	7	theme	surface	913:919	arg1	area					921:924	a large specific surface area	896:924	a large specific surface area	896:924	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	7	8	theme	cellulose	1188:1196	arg1	nanofibrils					1198:1208	cellulose nanofibrils	1188:1208	cellulose nanofibrils	1188:1208	It is believed that this study would provide an effective approach to preparing a photocatalyst and broaden the potential application of cellulose nanofibrils in photocatalysis.					
36264640	4	9	theme	photocatalytic	588:601	arg1	CMCN					532:535	The CMCN	528:535	The CMCN	528:535	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	4	9	theme	photocatalytic	588:601	arg1	performance					603:613	good photocatalytic performance	583:613	good photocatalytic performance	583:613	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	4	9	theme	photocatalytic	588:601	arg1	photocatalyst					555:567	a photocatalyst	553:567	a photocatalyst	553:567	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	0	10	theme	Nanofibrils/Ti3C2T	38:55	arg1	Heterojunction					70:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.					
36264640	6	11	theme	nanofibrils	831:841	arg1	incorporation					804:816	the incorporation	800:816	the incorporation of cellulose nanofibrils	800:841	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	7	12	theme	nanofibrils	1198:1208	arg1	application					1173:1183	the potential application	1159:1183	the potential application of cellulose nanofibrils in photocatalysis	1159:1226	It is believed that this study would provide an effective approach to preparing a photocatalyst and broaden the potential application of cellulose nanofibrils in photocatalysis.					
36264640	4	13	theme	good	583:586	arg1	CMCN					532:535	The CMCN	528:535	The CMCN	528:535	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	4	13	theme	good	583:586	arg1	performance					603:613	good photocatalytic performance	583:613	good photocatalytic performance	583:613	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	4	13	theme	good	583:586	arg1	photocatalyst					555:567	a photocatalyst	553:567	a photocatalyst	553:567	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	6	14	theme	cellulose	821:829	arg1	nanofibrils					831:841	cellulose nanofibrils	821:841	cellulose nanofibrils	821:841	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	1	15	theme	Photocatalytic	126:139	arg1	pollutants					151:160	Photocatalytic degrading pollutants	126:160	Photocatalytic degrading pollutants driven by visible-light irradiation	126:196	Photocatalytic degrading pollutants driven by visible-light irradiation has attracted tremendous attention.					
36264640	3	16	theme	morphology	479:488	arg1	terms					412:416	terms	412:416	terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties	412:525	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	7	17	theme	effective	1099:1107	arg1	approach					1109:1116	an effective approach	1096:1116	an effective approach to preparing a photocatalyst	1096:1145	It is believed that this study would provide an effective approach to preparing a photocatalyst and broaden the potential application of cellulose nanofibrils in photocatalysis.					
36264640	1	18	theme	degrading	141:149	arg1	pollutants					151:160	Photocatalytic degrading pollutants	126:160	Photocatalytic degrading pollutants driven by visible-light irradiation	126:196	Photocatalytic degrading pollutants driven by visible-light irradiation has attracted tremendous attention.					
36264640	3	19	theme	crystal	460:466	arg1	structure					468:476	chemical and crystal structure	447:476	structure	468:476	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	3	20	theme	as-prepared	358:368	arg1	CMCN					370:373	The as-prepared CMCN	354:373	The as-prepared CMCN	354:373	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	3	21	theme	structure	468:476	arg1	terms					412:416	terms	412:416	terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties	412:525	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	3	22	theme	photoelectrochemical	495:514	arg1	properties					516:525	photoelectrochemical properties	495:525	photoelectrochemical properties	495:525	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	6	23	theme	photocatalytic	972:985	arg1	performance					987:997	the photocatalytic performance	968:997	the photocatalytic performance	968:997	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	5	24	theme	good	751:754	arg1	reusability					756:766	good reusability	751:766	good reusability	751:766	In addition, the CMCN as a photocatalyst exhibited good reusability and stability.					
36264640	0	25	theme	Cellulose	28:36	arg1	Heterojunction					70:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.					
36264640	3	26	theme	properties	516:525	arg1	terms					412:416	terms	412:416	terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties	412:525	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	0	27	theme	Carbonized	17:26	arg1	Heterojunction					70:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.					
36264640	4	28	theme	visible-light	674:686	arg1	conditions					688:697	visible-light conditions	674:697	visible-light conditions	674:697	The CMCN was explored as a photocatalyst and exhibited good photocatalytic performance in degrading MB (96.5%), RhB (95.4%), and TC (86.5%) under visible-light conditions.					
36264640	0	29	theme	Heterojunction	70:83	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.	0:124	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.					
36264640	6	30	theme	specific	904:911	arg1	area					921:924	a large specific surface area	896:924	a large specific surface area	896:924	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	0	31	theme	MXene/g-C3N4	57:68	arg1	Heterojunction					70:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction	15:83	Fabrication of a Carbonized Cellulose Nanofibrils/Ti3C2T MXene/g-C3N4 Heterojunction for Visible-Light-Driven Photocatalysis.					
36264640	6	32	theme	high	877:880	arg1	content					866:872	a high carbon content	852:872	a high carbon content	852:872	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	6	32	theme	high	877:880	arg1	porosity					882:889	a high porosity	875:889	a high porosity	875:889	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	1	33	theme	visible-light	172:184	arg1	irradiation					186:196	visible-light irradiation	172:196	visible-light irradiation	172:196	Photocatalytic degrading pollutants driven by visible-light irradiation has attracted tremendous attention.					
36264640	2	34	theme	nanofibrils/Ti3C2T	281:298	arg1	photocatalyst					325:337	a photocatalyst	323:337	a photocatalyst	323:337	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	34	theme	nanofibrils/Ti3C2T	281:298	arg1	CMCN					314:317	CMCN	314:317	CMCN	314:317	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	34	theme	nanofibrils/Ti3C2T	281:298	arg1	MXene/g-C3N4					300:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4	260:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN)	260:318	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	35	theme	cellulose	271:279	arg1	photocatalyst					325:337	a photocatalyst	323:337	a photocatalyst	323:337	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	35	theme	cellulose	271:279	arg1	CMCN					314:317	CMCN	314:317	CMCN	314:317	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	35	theme	cellulose	271:279	arg1	MXene/g-C3N4					300:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4	260:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN)	260:318	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	36	theme	carbonized	260:269	arg1	photocatalyst					325:337	a photocatalyst	323:337	a photocatalyst	323:337	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	36	theme	carbonized	260:269	arg1	CMCN					314:317	CMCN	314:317	CMCN	314:317	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	2	36	theme	carbonized	260:269	arg1	MXene/g-C3N4					300:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4	260:311	carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN)	260:318	One strategy of preparing carbonized cellulose nanofibrils/Ti3C2T MXene/g-C3N4 (CMCN) as a photocatalyst was developed.					
36264640	6	37	theme	high	1035:1038	arg1	stability					1040:1048	a high stability	1033:1048	a high stability	1033:1048	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	3	38	theme	chemical	425:432	arg1	composition					434:444	the chemical composition	421:444	the chemical composition	421:444	The as-prepared CMCN was comprehensively characterized in terms of the chemical composition, chemical and crystal structure, morphology, and photoelectrochemical properties.					
36264640	6	39	theme	electron	940:947	arg1	transfer					949:956	the electron transfer	936:956	the electron transfer	936:956	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	6	40	with	semiconductor	1014:1026	arg1	stability					1040:1048	a high stability	1033:1048	a high stability	1033:1048	It is found that the incorporation of cellulose nanofibrils provided a high carbon content, a high porosity, and a large specific surface area, enhanced the electron transfer, improved the photocatalytic performance, and ensured a semiconductor with a high stability.					
36264640	1	41	theme	tremendous	212:221	arg1	attention					223:231	tremendous attention	212:231	tremendous attention	212:231	Photocatalytic degrading pollutants driven by visible-light irradiation has attracted tremendous attention.					
36206838	0	0	theme	gel	83:85	arg1	strength					87:94	gel strength	83:94	gel strength	83:94	Low temperature and freezing pretreatment for konjac glucomannan powder to improve gel strength.					
36206838	5	1	contain	has	650:652	arg1	gel					596:598	The gel	592:598	The gel prepared by freezing KGM powder at -18 °C for 8 h	592:648	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	5	1	contain	has	650:652	arg2	strength					667:674	the best gel strength	654:674	the best gel strength	654:674	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	8	2	theme	experimental	982:993	arg1	result					995:1000	experimental result	982:1000	experimental result	982:1000	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	1	3	theme	widespread	140:149	arg1	interest					151:158	widespread interest	140:158	widespread interest in the field of food	140:179	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	4	4	theme	analysis	488:495	arg1	result					462:467	result	462:467	result of texture profile analysis (TPA)	462:501	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	4	4	theme	analysis	488:495	arg1	test					516:519	puncture test	507:519	puncture test	507:519	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	8	5	theme	hydrogen	1171:1178	arg1	bond					1180:1183	hydrogen bond	1171:1183	hydrogen bond	1171:1183	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	4	6	theme	profile	480:486	arg1	TPA					498:500	TPA	498:500	TPA	498:500	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	4	6	theme	profile	480:486	arg1	analysis					488:495	texture profile analysis	472:495	texture profile analysis (TPA)	472:501	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	3	7	theme	processing	312:321	arg1	24 h					341:344	24 h	341:344	24 h	341:344	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	7	theme	processing	312:321	arg1	12 h					335:338	12 h	335:338	12 h	335:338	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	7	theme	processing	312:321	arg1	8 h					330:332	8 h	330:332	8 h	330:332	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	7	theme	processing	312:321	arg1	48 h					350:353	48 h	350:353	48 h	350:353	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	7	theme	processing	312:321	arg1	times					323:327	different processing times	302:327	different processing times (8 h, 12 h, 24 h and 48 h)	302:354	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	6	8	theme	KGM	754:756	arg1	weight					744:749	The molecular weight	730:749	The molecular weight of KGM	730:756	The molecular weight of KGM decreased significantly after pretreatment (from 12.30 × 105 Da to 0.29 × 105 Da).					
36206838	1	9	from	interest	151:158	arg1	field					167:171	the field	163:171	the field of food	163:179	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	9	10	theme	gel	1258:1260	arg1	properties					1262:1271	the gel properties	1254:1271	the gel properties	1254:1271	This study provides a convenient and effective method for improving the gel properties.					
36206838	3	11	theme	texture	403:409	arg1	properties					411:420	the texture properties	399:420	the texture properties of gels	399:428	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	9	12	theme	convenient	1208:1217	arg1	method					1233:1238	a convenient and effective method	1206:1238	a convenient and effective method for improving the gel properties	1206:1271	This study provides a convenient and effective method for improving the gel properties.					
36206838	8	13	theme	KGM	1114:1116	arg1	chain					1128:1132	KGM molecular chain	1114:1132	KGM molecular chain entangled	1114:1142	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	8	14	theme	low	1032:1034	arg1	temperature					1036:1046	low temperature	1032:1046	low temperature	1032:1046	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	4	15	theme	good	562:565	arg1	characteristics					575:589	good texture characteristics	562:589	good texture characteristics	562:589	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	8	16	theme	bond	1180:1183	arg1	number					1161:1166	the number	1157:1166	the number of hydrogen bond	1157:1183	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	3	17	theme	different	302:310	arg1	24 h					341:344	24 h	341:344	24 h	341:344	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	17	theme	different	302:310	arg1	12 h					335:338	12 h	335:338	12 h	335:338	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	17	theme	different	302:310	arg1	8 h					330:332	8 h	330:332	8 h	330:332	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	17	theme	different	302:310	arg1	48 h					350:353	48 h	350:353	48 h	350:353	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	17	theme	different	302:310	arg1	times					323:327	different processing times	302:327	different processing times (8 h, 12 h, 24 h and 48 h)	302:354	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	6	18	theme	molecular	734:742	arg1	weight					744:749	The molecular weight	730:749	The molecular weight of KGM	730:756	The molecular weight of KGM decreased significantly after pretreatment (from 12.30 × 105 Da to 0.29 × 105 Da).					
36206838	6	19	dep	decreased	758:766	arg1	0.29 × 105 Da					825:837	0.29 × 105 Da	825:837	0.29 × 105 Da	825:837	The molecular weight of KGM decreased significantly after pretreatment (from 12.30 × 105 Da to 0.29 × 105 Da).					
36206838	2	20	theme	further	235:241	arg1	application					243:253	its further application	231:253	its further application	231:253	However, the low texture properties of gel limit its further application.					
36206838	5	21	theme	native	718:723	arg1	KGM					725:727	native KGM	718:727	native KGM	718:727	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	2	22	theme	low	195:197	arg1	properties					207:216	the low texture properties	191:216	the low texture properties of gel	191:223	However, the low texture properties of gel limit its further application.					
36206838	0	23	theme	Low	0:2	arg1	temperature					4:14	Low temperature	0:14	Low temperature	0:14	Low temperature and freezing pretreatment for konjac glucomannan powder to improve gel strength.					
36206838	6	24	dep	0.29 × 105 Da	825:837	arg1	12.30 × 105 Da					807:820	12.30 × 105 Da	807:820	12.30 × 105 Da	807:820	The molecular weight of KGM decreased significantly after pretreatment (from 12.30 × 105 Da to 0.29 × 105 Da).					
36206838	8	25	theme	denser	1098:1103	arg1	structures					1087:1096	structures	1087:1096	structures denser	1087:1103	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	0	26	theme	freezing	20:27	arg1	pretreatment					29:40	freezing pretreatment	20:40	freezing pretreatment for konjac	20:51	Low temperature and freezing pretreatment for konjac glucomannan powder to improve gel strength.					
36206838	1	27	theme	Konjac	97:102	arg1	KGM					117:119	KGM	117:119	KGM	117:119	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	1	27	theme	Konjac	97:102	arg1	glucomannan					104:114	Konjac glucomannan	97:114	Konjac glucomannan (KGM) gel	97:124	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	1	28	theme	food	176:179	arg1	field					167:171	the field	163:171	the field of food	163:179	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	4	29	theme	texture	472:478	arg1	TPA					498:500	TPA	498:500	TPA	498:500	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	4	29	theme	texture	472:478	arg1	analysis					488:495	texture profile analysis	472:495	texture profile analysis (TPA)	472:501	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	7	30	theme	water	945:949	arg1	composite					951:959	water composite	945:959	water composite	945:959	In addition, low temperature and freezing treatment can influence the rheological behavior and regulate water composite in gel.					
36206838	1	31	theme	glucomannan	104:114	arg1	gel					122:124	Konjac glucomannan (KGM) gel	97:124	Konjac glucomannan (KGM) gel	97:124	Konjac glucomannan (KGM) gel has attracted widespread interest in the field of food.					
36206838	5	32	theme	best	658:661	arg1	strength					667:674	the best gel strength	654:674	the best gel strength	654:674	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	8	33	theme	chain	1128:1132	arg1	entangled					1134:1142	KGM molecular chain entangled	1114:1142	KGM molecular chain entangled	1114:1142	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	5	34	theme	gel	663:665	arg1	strength					667:674	the best gel strength	654:674	the best gel strength	654:674	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	5	35	theme	KGM	725:727	arg1	times					704:708	1.6 times	700:708	1.6 times that of native KGM	700:727	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	5	35	theme	KGM	725:727	arg1	sample					683:688	the sample	679:688	the sample	679:688	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	2	36	theme	texture	199:205	arg1	properties					207:216	the low texture properties	191:216	the low texture properties of gel	191:223	However, the low texture properties of gel limit its further application.					
36206838	7	37	theme	freezing	874:881	arg1	treatment					883:891	freezing treatment	874:891	freezing treatment	874:891	In addition, low temperature and freezing treatment can influence the rheological behavior and regulate water composite in gel.					
36206838	8	38	theme	molecular	1118:1126	arg1	chain					1128:1132	KGM molecular chain	1114:1132	KGM molecular chain entangled	1114:1142	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	5	39	theme	KGM	621:623	arg1	powder					625:630	KGM powder	621:630	KGM powder	621:630	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	3	40	dep	temperatures	360:371	arg1	-80 °C					388:393	-80 °C	388:393	-80 °C	388:393	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	40	dep	temperatures	360:371	arg1	-18 °C					380:385	-18 °C	380:385	-18 °C	380:385	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	40	dep	temperatures	360:371	arg1	4 °C					374:377	4 °C	374:377	4 °C	374:377	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	8	41	theme	crystal	1070:1076	arg1	temperature					1036:1046	low temperature	1032:1046	low temperature	1032:1046	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	8	41	theme	crystal	1070:1076	arg1	growth					1056:1061	the growth	1052:1061	the growth of ice crystal	1052:1076	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	7	42	theme	rheological	911:921	arg1	behavior					923:930	the rheological behavior	907:930	the rheological behavior	907:930	In addition, low temperature and freezing treatment can influence the rheological behavior and regulate water composite in gel.					
36206838	3	43	from	effect	275:280	arg1	properties					411:420	the texture properties	399:420	the texture properties of gels	399:428	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	8	44	theme	ice	1066:1068	arg1	crystal					1070:1076	ice crystal	1066:1076	ice crystal	1066:1076	According to experimental result, it can be attributed to that low temperature and the growth of ice crystal can make structures denser, promote KGM molecular chain entangled and increase the number of hydrogen bond.					
36206838	9	45	theme	effective	1223:1231	arg1	method					1233:1238	a convenient and effective method	1206:1238	a convenient and effective method for improving the gel properties	1206:1271	This study provides a convenient and effective method for improving the gel properties.					
36206838	5	46	dep	times	704:708	arg1	that					710:713	that	710:713	that	710:713	The gel prepared by freezing KGM powder at -18 °C for 8 h has the best gel strength in the sample, which is 1.6 times that of native KGM.					
36206838	3	47	dep	times	323:327	arg1	times					323:327	different processing times	302:327	different processing times (8 h, 12 h, 24 h and 48 h)	302:354	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	47	dep	times	323:327	arg1	24 h					341:344	24 h	341:344	24 h	341:344	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	47	dep	times	323:327	arg1	12 h					335:338	12 h	335:338	12 h	335:338	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	47	dep	times	323:327	arg1	8 h					330:332	8 h	330:332	8 h	330:332	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	47	dep	times	323:327	arg1	48 h					350:353	48 h	350:353	48 h	350:353	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	48	theme	gels	425:428	arg1	properties					411:420	the texture properties	399:420	the texture properties of gels	399:428	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	3	49	theme	KGM	285:287	arg1	powder					289:294	KGM powder	285:294	KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C)	285:394	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	2	50	theme	gel	221:223	arg1	properties					207:216	the low texture properties	191:216	the low texture properties of gel	191:223	However, the low texture properties of gel limit its further application.					
36206838	7	51	theme	low	854:856	arg1	temperature					858:868	low temperature	854:868	low temperature	854:868	In addition, low temperature and freezing treatment can influence the rheological behavior and regulate water composite in gel.					
36206838	3	52	theme	powder	289:294	arg1	effect					275:280	the effect	271:280	the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels	271:428	In this study, the effect of KGM powder under different processing times (8 h, 12 h, 24 h and 48 h) and temperatures (4 °C, -18 °C, -80 °C) on the texture properties of gels were investigated.					
36206838	4	53	theme	texture	567:573	arg1	characteristics					575:589	good texture characteristics	562:589	good texture characteristics	562:589	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
36206838	4	54	theme	puncture	507:514	arg1	test					516:519	puncture test	507:519	puncture test	507:519	According to result of texture profile analysis (TPA) and puncture test, the gel prepared by pretreatment showed good texture characteristics.					
37329650	0	0	theme	mof-199	72:78	arg1	bio-composite					80:92	chitosan@mof-199 bio-composite	63:92	chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	63:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	6	1	theme	urine	1075:1079	arg1	samples					1091:1097	urine (80-112%) samples	1075:1097	urine (80-112%) samples	1075:1097	Relative recoveries (RR%) for plasma (77-99%), saliva (81-108%), and urine (80-112%) samples were obtained.					
37329650	9	2	theme	beta-blocker	1410:1421	arg1	extraction					1428:1437	beta-blocker drug extraction	1410:1437	beta-blocker drug extraction in biological samples	1410:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	5	3	dep	three	941:945	arg1	replicates					947:956	replicates	947:956	replicates	947:956	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	0	4	theme	@	71:71	arg1	bio-composite					80:92	chitosan@mof-199 bio-composite	63:92	chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	63:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	9	5	theme	drug	1423:1426	arg1	extraction					1428:1437	beta-blocker drug extraction	1410:1437	beta-blocker drug extraction in biological samples	1410:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	3	6	theme	chitosan	479:486	arg1	bio-composite					496:508	chitosan@MOF-199 bio-composite	479:508	chitosan@MOF-199 bio-composite	479:508	A green approach was applied for synthesizing chitosan@MOF-199 bio-composite, which was packed into the initial part of a metal spinal (22 gage).					
37329650	1	7	theme	beta-blocker	225:236	arg1	drugs					238:242	three beta-blocker drugs	219:242	extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples	211:305	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	7	8	theme	drug	1133:1136	arg1	profile					1146:1152	the drug release profile	1129:1152	the drug release profile of propranolol in urine	1129:1176	In this study, the drug release profile of propranolol in urine was evaluated.					
37329650	8	9	theme	highest	1221:1227	arg1	propranolol					1239:1249	propranolol	1239:1249	propranolol	1239:1249	The results showed that the highest amount of propranolol is released 4 h after taking the drug.					
37329650	8	9	theme	highest	1221:1227	arg1	amount					1229:1234	the highest amount	1217:1234	the highest amount of propranolol	1217:1249	The results showed that the highest amount of propranolol is released 4 h after taking the drug.					
37329650	4	10	theme	cycle	699:703	arg1	numbers					705:711	cycle numbers	699:711	cycle numbers	699:711	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	5	11	theme	=	865:865	arg1	detection					849:857	detection	849:857	detection (LODs = 1.5-4.5 µg L-1)	849:881	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	11	theme	=	865:865	arg1	1.5-4.5 µg L-1					867:880	LODs = 1.5-4.5 µg L-1	860:880	LODs = 1.5-4.5 µg L-1	860:880	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	12	theme	detection	849:857	arg1	deviations					906:915	relative standard deviations	888:915	relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1)	888:989	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	12	theme	detection	849:857	arg1	limits					839:844	limits	839:844	limits of detection (LODs = 1.5-4.5 µg L-1)	839:881	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	12	theme	detection	849:857	arg1	ranges					810:815	linear ranges	803:815	linear ranges (LRs = 5-600 µg L-1)	803:836	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	7	13	from	profile	1146:1152	arg1	urine					1172:1176	urine	1172:1176	urine	1172:1176	In this study, the drug release profile of propranolol in urine was evaluated.					
37329650	4	14	theme	effective	583:591	arg1	parameters					593:602	The effective parameters	579:602	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent	579:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	0	15	theme	saliva	103:108	arg1	plasma					111:116	human saliva, plasma, and urine samples	97:135	plasma	111:116	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	4	16	theme	sample	661:666	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	9	17	theme	biological	1442:1451	arg1	samples					1453:1459	biological samples	1442:1459	biological samples	1442:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	2	18	theme	performance	373:383	arg1	chromatography					392:405	high performance liquid chromatography	368:405	high performance liquid chromatography followed by UV detection	368:430	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	9	19	theme	effective	1332:1340	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	19	theme	effective	1332:1340	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	4	20	theme	adsorption	611:620	arg1	volume					723:728	volume	723:728	volume of eluent solvent	723:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	20	theme	adsorption	611:620	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	20	theme	adsorption	611:620	arg1	numbers					705:711	cycle numbers	699:711	cycle numbers	699:711	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	20	theme	adsorption	611:620	arg1	efficiencies					637:648	the adsorption and desorption efficiencies	607:648	efficiencies	637:648	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	20	theme	adsorption	611:620	arg1	type					714:717	type	714:717	type	714:717	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	20	theme	adsorption	611:620	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	1	21	theme	current	142:148	arg1	study					150:154	The current study	138:154	The current study	138:154	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	0	22	theme	human	97:101	arg1	plasma					111:116	human saliva, plasma, and urine samples	97:135	plasma	111:116	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	9	23	theme	user-friendly	1385:1397	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	23	theme	user-friendly	1385:1397	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	5	24	with	%	934:934	arg1	three					941:945	three	941:945	three	941:945	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	7	25	theme	release	1138:1144	arg1	profile					1146:1152	the drug release profile	1129:1152	the drug release profile of propranolol in urine	1129:1176	In this study, the drug release profile of propranolol in urine was evaluated.					
37329650	2	26	theme	UV	419:420	arg1	detection					422:430	UV detection	419:430	UV detection	419:430	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	4	27	theme	eluent	681:686	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	volume					723:728	volume	723:728	volume of eluent solvent	723:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	numbers					705:711	cycle numbers	699:711	cycle numbers	699:711	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	efficiencies					637:648	the adsorption and desorption efficiencies	607:648	efficiencies	637:648	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	type					714:717	type	714:717	type	714:717	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	28	from	parameters	593:602	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	2	29	theme	drugs	344:348	arg1	detection					327:335	detection	327:335	detection	327:335	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	2	29	theme	drugs	344:348	arg1	separation					312:321	separation	312:321	separation	312:321	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	5	30	dep	=	822:822	arg1	5-600 µg L-1					824:835	5-600 µg L-1	824:835	5-600 µg L-1	824:835	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	31	dep	=	924:924	arg1	concentration					962:974	concentration	962:974	concentration of 100 µg L-1	962:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	31	dep	=	924:924	arg1	%					934:934	4.7 -5.3%	926:934	4.7 -5.3% with three replicates	926:956	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	31	dep	=	924:924	arg1	100 µg L-1					979:988	100 µg L-1	979:988	100 µg L-1	979:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	32	theme	optimal	784:790	arg1	conditions					792:801	optimal conditions	784:801	optimal conditions	784:801	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	3	33	theme	initial	537:543	arg1	part					545:548	the initial part	533:548	the initial part of a metal spinal (22 gage)	533:576	A green approach was applied for synthesizing chitosan@MOF-199 bio-composite, which was packed into the initial part of a metal spinal (22 gage).					
37329650	0	34	theme	β-blocker	42:50	arg1	drugs					52:56	some β-blocker drugs	37:56	some β-blocker drugs	37:56	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	8	35	theme	propranolol	1239:1249	arg1	propranolol					1239:1249	propranolol	1239:1249	propranolol	1239:1249	The results showed that the highest amount of propranolol is released 4 h after taking the drug.					
37329650	8	35	theme	propranolol	1239:1249	arg1	amount					1229:1234	the highest amount	1217:1234	the highest amount of propranolol	1217:1249	The results showed that the highest amount of propranolol is released 4 h after taking the drug.					
37329650	5	36	theme	LODs	860:863	arg1	detection					849:857	detection	849:857	detection (LODs = 1.5-4.5 µg L-1)	849:881	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	36	theme	LODs	860:863	arg1	1.5-4.5 µg L-1					867:880	LODs = 1.5-4.5 µg L-1	860:880	LODs = 1.5-4.5 µg L-1	860:880	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	9	37	theme	reproducible	1360:1371	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	37	theme	reproducible	1360:1371	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	2	38	theme	liquid	385:390	arg1	chromatography					392:405	high performance liquid chromatography	368:405	high performance liquid chromatography followed by UV detection	368:430	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	0	39	theme	packed	19:24	arg1	sorbent					26:32	packed sorbent	19:32	packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	19:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	9	40	theme	obtained	1303:1310	arg1	results					1312:1318	the obtained results	1299:1318	the obtained results	1299:1318	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	4	41	theme	flow	688:691	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	1	42	theme	packed	186:191	arg1	MEPS					202:205	MEPS	202:205	MEPS	202:205	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	1	42	theme	packed	186:191	arg1	sorbent					193:199	packed sorbent	186:199	packed sorbent (MEPS)	186:206	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	9	43	theme	fast	1343:1346	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	43	theme	fast	1343:1346	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	1	44	dep	extract	211:217	arg1	atenolol					258:265	atenolol	258:265	atenolol	258:265	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	1	44	dep	extract	211:217	arg1	betaxolol					272:280	betaxolol	272:280	betaxolol	272:280	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	1	44	dep	extract	211:217	arg1	propranolol					245:255	propranolol	245:255	propranolol	245:255	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	1	44	dep	extract	211:217	arg1	drugs					238:242	three beta-blocker drugs	219:242	extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples	211:305	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	4	45	theme	solvent	740:746	arg1	volume					723:728	volume	723:728	volume of eluent solvent	723:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	45	theme	solvent	740:746	arg1	type					714:717	type	714:717	type	714:717	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	45	theme	solvent	740:746	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	45	theme	solvent	740:746	arg1	numbers					705:711	cycle numbers	699:711	cycle numbers	699:711	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	45	theme	solvent	740:746	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	5	46	with	concentration	962:974	arg1	three					941:945	three	941:945	three	941:945	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	2	47	theme	high	368:371	arg1	chromatography					392:405	high performance liquid chromatography	368:405	high performance liquid chromatography followed by UV detection	368:430	The separation and detection of the drugs were performed by high performance liquid chromatography followed by UV detection.					
37329650	4	48	theme	desorption	626:635	arg1	volume					723:728	volume	723:728	volume of eluent solvent	723:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	48	theme	desorption	626:635	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	48	theme	desorption	626:635	arg1	numbers					705:711	cycle numbers	699:711	cycle numbers	699:711	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	48	theme	desorption	626:635	arg1	efficiencies					637:648	the adsorption and desorption efficiencies	607:648	efficiencies	637:648	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	48	theme	desorption	626:635	arg1	type					714:717	type	714:717	type	714:717	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	4	48	theme	desorption	626:635	arg1	rate					693:696	eluent flow rate	681:696	eluent flow rate	681:696	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	9	49	from	extraction	1428:1437	arg1	samples					1453:1459	biological samples	1442:1459	biological samples	1442:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	5	50	theme	linear	803:808	arg1	ranges					810:815	linear ranges	803:815	linear ranges (LRs = 5-600 µg L-1)	803:836	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	4	51	theme	eluent	733:738	arg1	solvent					740:746	eluent solvent	733:746	eluent solvent	733:746	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	0	52	with	sorbent	26:32	arg1	bio-composite					80:92	chitosan@mof-199 bio-composite	63:92	chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	63:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	0	53	theme	drugs	52:56	arg1	sorbent					26:32	packed sorbent	19:32	packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	19:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	5	54	theme	100 µg L-1	979:988	arg1	concentration					962:974	concentration	962:974	concentration of 100 µg L-1	962:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	54	theme	100 µg L-1	979:988	arg1	%					934:934	4.7 -5.3%	926:934	4.7 -5.3% with three replicates	926:956	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	54	theme	100 µg L-1	979:988	arg1	100 µg L-1					979:988	100 µg L-1	979:988	100 µg L-1	979:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	55	theme	=	924:924	arg1	%					922:922	RSDs%	918:922	RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1	918:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	3	56	theme	green	435:439	arg1	approach					441:448	A green approach	433:448	A green approach	433:448	A green approach was applied for synthesizing chitosan@MOF-199 bio-composite, which was packed into the initial part of a metal spinal (22 gage).					
37329650	1	57	from	samples	299:305	arg1	extract					211:217	extract	211:217	extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples	211:305	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	0	58	theme	urine	123:127	arg1	samples					129:135	human saliva, plasma, and urine samples	97:135	samples	129:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	9	59	theme	green	1374:1378	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	59	theme	green	1374:1378	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	7	60	theme	propranolol	1157:1167	arg1	profile					1146:1152	the drug release profile	1129:1152	the drug release profile of propranolol in urine	1129:1176	In this study, the drug release profile of propranolol in urine was evaluated.					
37329650	5	61	theme	relative	888:895	arg1	deviations					906:915	relative standard deviations	888:915	relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1)	888:989	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	5	62	dep	ranges	810:815	arg1	LRs					818:820	LRs	818:820	LRs	818:820	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	6	63	theme	Relative	1006:1013	arg1	recoveries					1015:1024	Relative recoveries	1006:1024	Relative recoveries (RR%) for plasma (77-99%), saliva (81-108%), and urine (80-112%) samples	1006:1097	Relative recoveries (RR%) for plasma (77-99%), saliva (81-108%), and urine (80-112%) samples were obtained.					
37329650	6	63	theme	Relative	1006:1013	arg1	%					1029:1029	RR%	1027:1029	RR%	1027:1029	Relative recoveries (RR%) for plasma (77-99%), saliva (81-108%), and urine (80-112%) samples were obtained.					
37329650	5	64	theme	standard	897:904	arg1	deviations					906:915	relative standard deviations	888:915	relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1)	888:989	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	4	65	theme	solution	668:675	arg1	pH					677:678	sample solution pH	661:678	sample solution pH	661:678	The effective parameters on the adsorption and desorption efficiencies, including sample solution pH, eluent flow rate, cycle numbers, type and volume of eluent solvent were evaluated and optimized.					
37329650	0	66	theme	chitosan	63:70	arg1	bio-composite					80:92	chitosan@mof-199 bio-composite	63:92	chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples	63:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	0	67	from	bio-composite	80:92	arg1	samples					129:135	human saliva, plasma, and urine samples	97:135	samples	129:135	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	0	67	from	bio-composite	80:92	arg1	plasma					111:116	human saliva, plasma, and urine samples	97:135	plasma	111:116	Microextraction by packed sorbent of some β-blocker drugs with chitosan@mof-199 bio-composite in human saliva, plasma, and urine samples.					
37329650	3	68	theme	spinal	561:566	arg1	part					545:548	the initial part	533:548	the initial part of a metal spinal (22 gage)	533:576	A green approach was applied for synthesizing chitosan@MOF-199 bio-composite, which was packed into the initial part of a metal spinal (22 gage).					
37329650	5	69	dep	deviations	906:915	arg1	%					922:922	RSDs%	918:922	RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1	918:988	Under optimal conditions linear ranges (LRs = 5-600 µg L-1), limits of detection (LODs = 1.5-4.5 µg L-1), and relative standard deviations (RSDs% = 4.7 -5.3% with three replicates and concentration of 100 µg L-1) were obtained.					
37329650	3	70	theme	@	487:487	arg1	bio-composite					496:508	chitosan@MOF-199 bio-composite	479:508	chitosan@MOF-199 bio-composite	479:508	A green approach was applied for synthesizing chitosan@MOF-199 bio-composite, which was packed into the initial part of a metal spinal (22 gage).					
37329650	1	71	theme	biological	288:297	arg1	samples					299:305	biological samples	288:305	biological samples	288:305	The current study introduces microextraction by packed sorbent (MEPS) to extract three beta-blocker drugs (propranolol, atenolol, and betaxolol) from biological samples.					
37329650	9	72	theme	sensitive	1349:1357	arg1	method					1399:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method	1329:1404	an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples	1329:1459	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
37329650	9	72	theme	sensitive	1349:1357	arg1	this					1321:1324	this	1321:1324	this	1321:1324	Based on the obtained results, this is an effective, fast, sensitive, reproducible, green, and user-friendly method for beta-blocker drug extraction in biological samples.					
36174084	11	0	theme	larval	1919:1924	arg1	development					1926:1936	larval development	1919:1936	larval development	1919:1936	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	11	1	from	larvae	1826:1831	arg1	substrate					1812:1820	the substrate	1808:1820	the substrate	1808:1820	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	10	2	theme	marine-based	1542:1553	arg1	substrates					1561:1570	marine-based waste substrates	1542:1570	marine-based waste substrates	1542:1570	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	7	3	theme	nutritional	1292:1302	arg1	composition					1304:1314	their nutritional composition	1286:1314	their nutritional composition	1286:1314	Larval body weight was recorded daily to determine growth over time whereas larvae and substrates were sampled at the start and end of the trial and analysed for their nutritional composition.					
36174084	6	4	theme	chicken	1109:1115	arg1	feed					1117:1120	chicken feed	1109:1120	chicken feed	1109:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	11	5	theme	larval	1841:1846	arg1	lipid					1848:1852	larval lipid	1841:1852	larval lipid	1841:1852	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	1	6	theme	soldier	155:161	arg1	larvae					187:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	9	7	theme	fatty	1512:1516	arg1	acids					1518:1522	certain fatty acids	1504:1522	certain fatty acids	1504:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	6	8	theme	similar	1072:1078	arg1	composition					1094:1104	a similar macronutrient composition	1070:1104	a similar macronutrient composition to chicken feed	1070:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	10	9	theme	acids	1614:1618	arg1	share					1591:1595	a higher share	1582:1595	a higher share of omega-3 fatty acids	1582:1618	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	9	10	theme	substrate	1479:1487	arg1	composition					1460:1470	the nutritional composition	1444:1470	the nutritional composition of the substrate and larvae for certain fatty acids	1444:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	6	11	dep	feed	1018:1021	arg1	mixture					1024:1030	mixture	1024:1030	mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed	1024:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	1	12	theme	illucens	177:184	arg1	larvae					187:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	11	13	theme	amino	1864:1868	arg1	acid					1870:1873	amino acid	1864:1873	amino acid	1864:1873	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	0	14	theme	larval	108:113	arg1	composition					120:130	larval body composition	108:130	larval body composition	108:130	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	11	15	theme	ash	1793:1795	arg1	content					1797:1803	the ash content	1789:1803	the ash content in the substrate	1789:1820	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	5	16	theme	different	736:744	arg1	waste					764:768	different locally available waste	736:768	different locally available waste	736:768	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	3	17	theme	larval	473:478	arg1	composition					485:495	the larval body composition	469:495	the larval body composition	469:495	Hitherto, it remains unclear how and to what extent the larval body composition can be altered by the substrate.					
36174084	11	18	theme	chitin	1880:1885	arg1	content					1887:1893	chitin content	1880:1893	chitin content	1880:1893	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	12	19	theme	further	2115:2121	arg1	food					2123:2126	further food	2115:2126	further food	2115:2126	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	4	20	theme	body	614:617	arg1	composition					619:629	larval body composition	607:629	larval body composition	607:629	This study was therefore performed to examine the possibilities of modifying larval body composition using different rearing substrates.					
36174084	5	21	theme	mitigation	809:818	arg1	mussels					820:826	mitigation mussels	809:826	mitigation mussels (Mytilus edulis)	809:843	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	21	theme	mitigation	809:818	arg1	edulis					837:842	Mytilus edulis	829:842	Mytilus edulis	829:842	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	6	22	with	by-products	1052:1062	arg1	composition					1094:1104	a similar macronutrient composition	1070:1104	a similar macronutrient composition to chicken feed	1070:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	2	23	theme	nutritional	398:408	arg1	value					410:414	its nutritional value	394:414	its nutritional value	394:414	However, the type of rearing substrate also affects the larval body composition and thus its nutritional value.					
36174084	6	24	theme	chicken	1035:1041	arg1	feed					1043:1046	chicken feed	1035:1046	chicken feed	1035:1046	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	0	25	theme	soldier	57:63	arg1	larvae					89:94	black soldier fly (Hermetia illucens) larvae	51:94	black soldier fly (Hermetia illucens) larvae	51:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	10	26	theme	other	1646:1650	arg1	substrates					1652:1661	the other substrates	1642:1661	the other substrates	1642:1661	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	0	27	theme	illucens	79:86	arg1	larvae					89:94	black soldier fly (Hermetia illucens) larvae	51:94	black soldier fly (Hermetia illucens) larvae	51:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	6	28	with	feed	1043:1046	arg1	composition					1094:1104	a similar macronutrient composition	1070:1104	a similar macronutrient composition to chicken feed	1070:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	1	29	dep	matter	272:277	arg1	DM					280:281	DM	280:281	DM	280:281	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	30	theme	~30	295:297	arg1	%					298:298	%	298:298	%	298:298	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	12	31	theme	nutrients	2076:2084	arg1	composition					2053:2063	larval composition	2046:2063	larval composition of certain nutrients	2046:2084	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	1	32	theme	high	246:249	arg1	mass					241:244	body mass	236:244	body mass high in protein (~40% dry matter, DM) and lipid (~30% DM)	236:302	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	2	33	theme	substrate	334:342	arg1	type					318:321	the type	314:321	the type of rearing substrate	314:342	However, the type of rearing substrate also affects the larval body composition and thus its nutritional value.					
36174084	8	34	theme	body	1368:1371	arg1	composition					1373:1383	larval body composition	1361:1383	larval body composition	1361:1383	The type of rearing substrate affected both larval body composition and growth performance.					
36174084	4	35	theme	rearing	647:653	arg1	substrates					655:664	different rearing substrates	637:664	different rearing substrates	637:664	This study was therefore performed to examine the possibilities of modifying larval body composition using different rearing substrates.					
36174084	11	36	theme	positive	1753:1760	arg1	correlation					1769:1779	a strong positive linear correlation	1744:1779	a strong positive linear correlation between the ash content in the substrate and larvae	1744:1831	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	9	37	dep	substrate	1479:1487	arg1	the					1475:1477	the	1475:1477	the	1475:1477	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	6	38	theme	Larval	904:909	arg1	composition					911:921	Larval composition	904:921	Larval composition	904:921	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	0	39	theme	rearing	28:34	arg1	substrates					36:45	rearing substrates	28:45	rearing substrates for black soldier fly (Hermetia illucens) larvae	28:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	9	40	theme	clear	1421:1425	arg1	relation					1427:1434	a clear relation	1419:1434	a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids	1419:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	7	41	theme	body	1131:1134	arg1	weight					1136:1141	Larval body weight	1124:1141	Larval body weight	1124:1141	Larval body weight was recorded daily to determine growth over time whereas larvae and substrates were sampled at the start and end of the trial and analysed for their nutritional composition.					
36174084	2	42	theme	larval	361:366	arg1	composition					373:383	the larval body composition	357:383	the larval body composition	357:383	However, the type of rearing substrate also affects the larval body composition and thus its nutritional value.					
36174084	12	43	theme	larval	2001:2006	arg1	composition					2008:2018	larval composition	2001:2018	larval composition	2001:2018	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	5	44	theme	old	695:697	arg1	larvae					699:704	5-days old larvae	688:704	5-days old larvae	688:704	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	1	45	theme	dry	268:270	arg1	protein					254:260	protein	254:260	protein (~40% dry matter, DM)	254:282	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	45	theme	dry	268:270	arg1	matter					272:277	~40% dry matter	263:277	~40% dry matter	263:277	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	6	46	theme	chicken	986:992	arg1	feed					994:997	a commercial chicken feed	973:997	a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed)	973:1121	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	9	47	theme	nutritional	1448:1458	arg1	composition					1460:1470	the nutritional composition	1444:1470	the nutritional composition of the substrate and larvae for certain fatty acids	1444:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	10	48	theme	fatty	1702:1706	arg1	acids					1708:1712	omega-3 fatty acids	1694:1712	omega-3 fatty acids from the substrate	1694:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	0	49	theme	black	51:55	arg1	larvae					89:94	black soldier fly (Hermetia illucens) larvae	51:94	black soldier fly (Hermetia illucens) larvae	51:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	5	50	theme	waste	872:876	arg1	meal					878:881	shrimp waste meal	865:881	shrimp waste meal (Pandalus borealis)	865:901	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	50	theme	waste	872:876	arg1	borealis					893:900	Pandalus borealis	884:900	Pandalus borealis	884:900	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	0	51	from	Effects	97:103	arg1	performance					136:146	performance	136:146	performance	136:146	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	0	51	from	Effects	97:103	arg1	composition					120:130	larval body composition	108:130	larval body composition	108:130	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	10	52	theme	waste	1555:1559	arg1	substrates					1561:1570	marine-based waste substrates	1542:1570	marine-based waste substrates	1542:1570	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	1	53	from	high	246:249	arg1	protein					254:260	protein	254:260	protein (~40% dry matter, DM)	254:282	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	53	from	high	246:249	arg1	DM					300:301	~30% DM	295:301	~30% DM	295:301	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	53	from	high	246:249	arg1	lipid					288:292	lipid	288:292	lipid (~30% DM)	288:302	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	53	from	high	246:249	arg1	matter					272:277	~40% dry matter	263:277	~40% dry matter	263:277	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	54	theme	body	236:239	arg1	mass					241:244	body mass	236:244	body mass high in protein (~40% dry matter, DM) and lipid (~30% DM)	236:302	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	9	55	theme	larvae	1493:1498	arg1	composition					1460:1470	the nutritional composition	1444:1470	the nutritional composition of the substrate and larvae for certain fatty acids	1444:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	11	56	from	content	1797:1803	arg1	substrate					1812:1820	the substrate	1808:1820	the substrate	1808:1820	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	1	57	from	protein	254:260	arg1	high					246:249	high	246:249	high	246:249	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	10	58	theme	higher	1584:1589	arg1	share					1591:1595	a higher share	1582:1595	a higher share of omega-3 fatty acids	1582:1618	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	1	59	theme	Black	149:153	arg1	larvae					187:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	7	60	theme	trial	1263:1267	arg1	end					1252:1254	the start and end	1238:1254	end	1252:1254	Larval body weight was recorded daily to determine growth over time whereas larvae and substrates were sampled at the start and end of the trial and analysed for their nutritional composition.					
36174084	7	60	theme	trial	1263:1267	arg1	start					1242:1246	the start and end	1238:1254	start	1242:1246	Larval body weight was recorded daily to determine growth over time whereas larvae and substrates were sampled at the start and end of the trial and analysed for their nutritional composition.					
36174084	9	61	theme	certain	1504:1510	arg1	acids					1518:1522	certain fatty acids	1504:1522	certain fatty acids	1504:1522	There was a clear relation between the nutritional composition of the substrate and larvae for certain fatty acids.					
36174084	6	62	theme	mixed	1012:1016	arg1	feed					1018:1021	a mixed feed	1010:1021	a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed)	973:1121	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	6	63	theme	macronutrient	1080:1092	arg1	composition					1094:1104	a similar macronutrient composition	1070:1104	a similar macronutrient composition to chicken feed	1070:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	1	64	theme	fly	163:165	arg1	larvae					187:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	10	65	from	substrate	1723:1731	arg1	acids					1708:1712	omega-3 fatty acids	1694:1712	omega-3 fatty acids from the substrate	1694:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	10	65	from	substrate	1723:1731	arg1	accumulation					1678:1689	an accumulation	1675:1689	an accumulation of omega-3 fatty acids from the substrate	1675:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	10	66	theme	fatty	1608:1612	arg1	acids					1614:1618	omega-3 fatty acids	1600:1618	omega-3 fatty acids	1600:1618	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	1	67	theme	Hermetia	168:175	arg1	larvae					187:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae	149:192	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	5	68	dep	investigate	670:680	arg1	grain					802:806	brewer's spent grain	787:806	brewer's spent grain	787:806	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	68	dep	investigate	670:680	arg1	meal					878:881	shrimp waste meal	865:881	shrimp waste meal (Pandalus borealis)	865:901	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	68	dep	investigate	670:680	arg1	cake					855:858	rapeseed cake	846:858	rapeseed cake	846:858	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	68	dep	investigate	670:680	arg1	mussels					820:826	mitigation mussels	809:826	mitigation mussels (Mytilus edulis)	809:843	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	68	dep	investigate	670:680	arg1	borealis					893:900	Pandalus borealis	884:900	Pandalus borealis	884:900	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	68	dep	investigate	670:680	arg1	edulis					837:842	Mytilus edulis	829:842	Mytilus edulis	829:842	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	0	69	theme	body	115:118	arg1	composition					120:130	larval body composition	108:130	larval body composition	108:130	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	3	70	theme	body	480:483	arg1	composition					485:495	the larval body composition	469:495	the larval body composition	469:495	Hitherto, it remains unclear how and to what extent the larval body composition can be altered by the substrate.					
36174084	5	71	theme	spent	796:800	arg1	grain					802:806	brewer's spent grain	787:806	brewer's spent grain	787:806	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	12	72	theme	food	2123:2126	arg1	applications					2137:2148	further food and feed applications	2115:2148	further food and feed applications	2115:2148	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	6	73	theme	by-products	1052:1062	arg1	mixture					1024:1030	mixture	1024:1030	mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed	1024:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	5	74	from	days	728:731	arg1	by-products					774:784	by-products	774:784	by-products	774:784	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	74	from	days	728:731	arg1	waste					764:768	different locally available waste	736:768	different locally available waste	736:768	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	10	75	contain	contained	1572:1580	arg1	Larvae					1525:1530	Larvae	1525:1530	Larvae reared on marine-based waste substrates	1525:1570	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	10	75	contain	contained	1572:1580	arg2	share					1591:1595	a higher share	1582:1595	a higher share of omega-3 fatty acids	1582:1618	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	12	76	theme	feed	2132:2135	arg1	applications					2137:2148	further food and feed applications	2115:2148	further food and feed applications	2115:2148	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	6	77	theme	feed	1043:1046	arg1	mixture					1024:1030	mixture	1024:1030	mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed	1024:1120	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	4	78	theme	larval	607:612	arg1	composition					619:629	larval body composition	607:629	larval body composition	607:629	This study was therefore performed to examine the possibilities of modifying larval body composition using different rearing substrates.					
36174084	0	79	theme	fly	65:67	arg1	larvae					89:94	black soldier fly (Hermetia illucens) larvae	51:94	black soldier fly (Hermetia illucens) larvae	51:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	0	80	theme	Hermetia	70:77	arg1	larvae					89:94	black soldier fly (Hermetia illucens) larvae	51:94	black soldier fly (Hermetia illucens) larvae	51:94	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	8	81	theme	rearing	1329:1335	arg1	substrate					1337:1345	rearing substrate	1329:1345	rearing substrate	1329:1345	The type of rearing substrate affected both larval body composition and growth performance.					
36174084	12	82	theme	certain	2068:2074	arg1	nutrients					2076:2084	certain nutrients	2068:2084	certain nutrients	2068:2084	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	5	83	theme	rapeseed	846:853	arg1	cake					855:858	rapeseed cake	846:858	rapeseed cake	846:858	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	8	84	theme	larval	1361:1366	arg1	composition					1373:1383	larval body composition	1361:1383	larval body composition	1361:1383	The type of rearing substrate affected both larval body composition and growth performance.					
36174084	12	85	theme	larval	2046:2051	arg1	composition					2053:2063	larval composition	2046:2063	larval composition of certain nutrients	2046:2084	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	1	86	theme	%	298:298	arg1	DM					300:301	~30% DM	295:301	~30% DM	295:301	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	86	theme	%	298:298	arg1	lipid					288:292	lipid	288:292	lipid (~30% DM)	288:302	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	8	87	theme	substrate	1337:1345	arg1	type					1321:1324	The type	1317:1324	The type of rearing substrate	1317:1345	The type of rearing substrate affected both larval body composition and growth performance.					
36174084	1	88	from	lipid	288:292	arg1	high					246:249	high	246:249	high	246:249	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	5	89	theme	Mytilus	829:835	arg1	mussels					820:826	mitigation mussels	809:826	mitigation mussels (Mytilus edulis)	809:843	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	89	theme	Mytilus	829:835	arg1	edulis					837:842	Mytilus edulis	829:842	Mytilus edulis	829:842	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	2	90	theme	rearing	326:332	arg1	substrate					334:342	rearing substrate	326:342	rearing substrate	326:342	However, the type of rearing substrate also affects the larval body composition and thus its nutritional value.					
36174084	8	91	theme	growth	1389:1394	arg1	performance					1396:1406	growth performance	1389:1406	growth performance	1389:1406	The type of rearing substrate affected both larval body composition and growth performance.					
36174084	10	92	theme	omega-3	1694:1700	arg1	acids					1708:1712	omega-3 fatty acids	1694:1712	omega-3 fatty acids from the substrate	1694:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	4	93	theme	different	637:645	arg1	substrates					655:664	different rearing substrates	637:664	different rearing substrates	637:664	This study was therefore performed to examine the possibilities of modifying larval body composition using different rearing substrates.					
36174084	11	94	theme	linear	1762:1767	arg1	correlation					1769:1779	a strong positive linear correlation	1744:1779	a strong positive linear correlation between the ash content in the substrate and larvae	1744:1831	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	7	95	theme	Larval	1124:1129	arg1	weight					1136:1141	Larval body weight	1124:1141	Larval body weight	1124:1141	Larval body weight was recorded daily to determine growth over time whereas larvae and substrates were sampled at the start and end of the trial and analysed for their nutritional composition.					
36174084	2	96	theme	body	368:371	arg1	composition					373:383	the larval body composition	357:383	the larval body composition	357:383	However, the type of rearing substrate also affects the larval body composition and thus its nutritional value.					
36174084	12	97	theme	rearing	1975:1981	arg1	substrate					1983:1991	the rearing substrate	1971:1991	the rearing substrate	1971:1991	Overall, this study showed that the rearing substrate affects larval composition and development, and that larval composition of certain nutrients can be tailored depending on further food and feed applications.					
36174084	11	98	theme	strong	1746:1751	arg1	correlation					1769:1779	a strong positive linear correlation	1744:1779	a strong positive linear correlation between the ash content in the substrate and larvae	1744:1831	There was a strong positive linear correlation between the ash content in the substrate and larvae whereas larval lipid, protein, amino acid, and chitin content seemed more affected by larval development.					
36174084	5	99	theme	5-days	688:693	arg1	larvae					699:704	5-days old larvae	688:704	5-days old larvae	688:704	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	1	100	theme	%	266:266	arg1	protein					254:260	protein	254:260	protein (~40% dry matter, DM)	254:282	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	1	100	theme	%	266:266	arg1	matter					272:277	~40% dry matter	263:277	~40% dry matter	263:277	Black soldier fly (Hermetia illucens) larvae can convert biowaste and by-products into body mass high in protein (~40% dry matter, DM) and lipid (~30% DM).					
36174084	5	101	theme	Pandalus	884:891	arg1	meal					878:881	shrimp waste meal	865:881	shrimp waste meal (Pandalus borealis)	865:901	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	101	theme	Pandalus	884:891	arg1	borealis					893:900	Pandalus borealis	884:900	Pandalus borealis	884:900	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	0	102	dep	Biowaste	0:7	arg1	Effects					97:103	Effects	97:103	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.	0:147	Biowaste and by-products as rearing substrates for black soldier fly (Hermetia illucens) larvae: Effects on larval body composition and performance.					
36174084	6	103	theme	commercial	975:984	arg1	feed					994:997	a commercial chicken feed	973:997	a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed)	973:1121	Larval composition and performance were compared to larvae reared on a commercial chicken feed as well as a mixed feed (mixture of chicken feed and by-products, with a similar macronutrient composition to chicken feed).					
36174084	10	104	theme	acids	1708:1712	arg1	accumulation					1678:1689	an accumulation	1675:1689	an accumulation of omega-3 fatty acids from the substrate	1675:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	5	105	dep	different	736:744	arg1	available					754:762	available	754:762	available	754:762	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	10	106	from	accumulation	1678:1689	arg1	substrate					1723:1731	the substrate	1719:1731	the substrate	1719:1731	Larvae reared on marine-based waste substrates contained a higher share of omega-3 fatty acids than larvae reared on the other substrates, indicating an accumulation of omega-3 fatty acids from the substrate.					
36174084	5	107	theme	shrimp	865:870	arg1	meal					878:881	shrimp waste meal	865:881	shrimp waste meal (Pandalus borealis)	865:901	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36174084	5	107	theme	shrimp	865:870	arg1	borealis					893:900	Pandalus borealis	884:900	Pandalus borealis	884:900	To investigate this, 5-days old larvae were reared for seven days on different locally available waste and by-products: brewer's spent grain, mitigation mussels (Mytilus edulis), rapeseed cake, and shrimp waste meal (Pandalus borealis).					
36331041	7	0	theme	positive	1478:1485	arg1	association					1487:1497	a positive association	1476:1497	a positive association with conjugated bile acids and serum TC	1476:1537	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	1	theme	Proteobacteria	1431:1444	arg1	abundance					1418:1426	the abundance	1414:1426	the abundance of Proteobacteria and Lachnoclosteridium	1414:1467	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	4	2	theme	cholesterol	863:873	arg1	uptake					875:880	the hepatic cholesterol uptake	851:880	the hepatic cholesterol uptake	851:880	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	2	3	theme	male	369:372	arg1	mice					383:386	fifty male C57BL/6J mice	363:386	fifty male C57BL/6J mice	363:386	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	3	4	theme	cholesterol	676:686	arg1	concentrations					652:665	serum concentrations	646:665	serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C)	646:739	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	2	5	theme	treatment	476:484	arg1	groups					486:491	3 treatment groups	474:491	3 treatment groups	474:491	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	7	6	theme	Lachnoclosteridium	1450:1467	arg1	abundance					1418:1426	the abundance	1414:1426	the abundance of Proteobacteria and Lachnoclosteridium	1414:1467	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	4	7	theme	gene	824:827	arg1	expression					829:838	the gene expression	820:838	the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway	820:912	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	7	8	theme	Further	1204:1210	arg1	analysis					1224:1231	Further correlation analysis	1204:1231	Further correlation analysis	1204:1231	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	8	9	theme	favorable	1681:1689	arg1	composition					1708:1718	a favorable fecal microbiota composition	1679:1718	a favorable fecal microbiota composition	1679:1718	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	0	10	theme	acid	118:121	arg1	metabolism					123:132	the gut microbiota and bile acid metabolism	90:132	metabolism	123:132	Polysaccharides from Enteromorpha prolifera alleviate hypercholesterolemia via modulating the gut microbiota and bile acid metabolism.					
36331041	7	11	theme	fecal	1356:1360	arg1	acids					1378:1382	fecal conjugated bile acids	1356:1382	fecal conjugated bile acids	1356:1382	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	6	12	theme	conjugated	1181:1190	arg1	acids					1197:1201	fecal conjugated bile acids	1175:1201	fecal conjugated bile acids	1175:1201	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	6	13	theme	bile	1146:1149	arg1	profile					1156:1162	the fecal bile acid profile	1136:1162	the fecal bile acid profile	1136:1162	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	7	14	with	correlation	1256:1266	arg1	levels					1346:1351	the levels	1342:1351	the levels of fecal conjugated bile acids and serum TC and LDL-C	1342:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	3	15	theme	cholesterol	763:773	arg1	deposition					775:784	hepatic cholesterol deposition	755:784	hepatic cholesterol deposition	755:784	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	0	16	theme	bile	113:116	arg1	metabolism					123:132	the gut microbiota and bile acid metabolism	90:132	metabolism	123:132	Polysaccharides from Enteromorpha prolifera alleviate hypercholesterolemia via modulating the gut microbiota and bile acid metabolism.					
36331041	1	17	contain	possess	184:190	arg1	Polysaccharides					135:149	Polysaccharides	135:149	Polysaccharides from Enteromorpha prolifera (EP)	135:182	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	1	17	contain	possess	184:190	arg2	activities					212:221	multiple biological activities	192:221	multiple biological activities	192:221	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	4	18	theme	related	840:846	arg1	expression					829:838	the gene expression	820:838	the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway	820:912	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	6	19	theme	fecal	1140:1144	arg1	profile					1156:1162	the fecal bile acid profile	1136:1162	the fecal bile acid profile	1136:1162	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	7	20	with	association	1487:1497	arg1	acids					1520:1524	conjugated bile acids	1504:1524	conjugated bile acids	1504:1524	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	20	with	association	1487:1497	arg1	TC					1536:1537	serum TC	1530:1537	serum TC	1530:1537	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	2	21	theme	HFHC	505:508	arg1	diet					510:513	an HFHC diet	502:513	an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1)	502:588	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	8	22	theme	microbiota	1697:1706	arg1	composition					1708:1718	a favorable fecal microbiota composition	1679:1718	a favorable fecal microbiota composition	1679:1718	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	7	23	theme	acids	1378:1382	arg1	levels					1346:1351	the levels	1342:1351	the levels of fecal conjugated bile acids and serum TC and LDL-C	1342:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	24	theme	conjugated	1362:1371	arg1	acids					1378:1382	fecal conjugated bile acids	1356:1382	fecal conjugated bile acids	1356:1382	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	8	25	theme	fecal	1691:1695	arg1	composition					1708:1718	a favorable fecal microbiota composition	1679:1718	a favorable fecal microbiota composition	1679:1718	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	1	26	theme	multiple	192:199	arg1	activities					212:221	multiple biological activities	192:221	multiple biological activities	192:221	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	6	27	theme	acid	1085:1088	arg1	analysis					1098:1105	bile acid profile analysis	1080:1105	bile acid profile analysis	1080:1105	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	1	28	theme	biological	201:210	arg1	activities					212:221	multiple biological activities	192:221	multiple biological activities	192:221	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	2	29	theme	high-cholesterol	447:462	arg1	diet					464:467	a high-fat and high-cholesterol diet	432:467	a high-fat and high-cholesterol diet	432:467	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	3	30	theme	total	670:674	arg1	TC					689:690	TC	689:690	TC	689:690	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	3	30	theme	total	670:674	arg1	cholesterol					676:686	total cholesterol	670:686	total cholesterol (TC)	670:691	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	1	31	from	prolifera	169:177	arg1	Polysaccharides					135:149	Polysaccharides	135:149	Polysaccharides from Enteromorpha prolifera (EP)	135:182	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	7	32	theme	TC	1394:1395	arg1	levels					1346:1351	the levels	1342:1351	the levels of fecal conjugated bile acids and serum TC and LDL-C	1342:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	33	theme	Muribaculaceae	1294:1307	arg1	correlation					1256:1266	the negative correlation	1243:1266	the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C	1243:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	4	34	theme	synthetic	896:904	arg1	pathway					906:912	bile acid synthetic pathway	886:912	bile acid synthetic pathway	886:912	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	1	35	theme	gut	299:301	arg1	microbiota					303:312	the gut microbiota	295:312	the gut microbiota	295:312	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	2	36	theme	kg-1	578:581	arg1	day-1					583:587	kg-1 day-1	578:587	kg-1 day-1	578:587	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	8	37	theme	bile	1733:1736	arg1	metabolism					1743:1752	bile acid metabolism	1733:1752	bile acid metabolism	1733:1752	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	2	38	theme	high-fat	434:441	arg1	diet					464:467	a high-fat and high-cholesterol diet	432:467	a high-fat and high-cholesterol diet	432:467	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	3	39	theme	low-density	697:707	arg1	cholesterol					721:731	low-density lipoprotein cholesterol	697:731	low-density lipoprotein cholesterol (LDL-C)	697:739	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	3	39	theme	low-density	697:707	arg1	LDL-C					734:738	LDL-C	734:738	LDL-C	734:738	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	1	40	with	role	234:237	arg1	microbiota					303:312	the gut microbiota	295:312	the gut microbiota	295:312	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	6	41	theme	fecal	1175:1179	arg1	acids					1197:1201	fecal conjugated bile acids	1175:1201	fecal conjugated bile acids	1175:1201	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	7	42	dep	Muribaculaceae	1294:1307	arg1	abundance					1327:1335	abundance	1327:1335	abundance	1327:1335	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	8	43	theme	acid	1738:1741	arg1	metabolism					1743:1752	bile acid metabolism	1733:1752	bile acid metabolism	1733:1752	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	7	44	theme	serum	1530:1534	arg1	TC					1536:1537	serum TC	1530:1537	serum TC	1530:1537	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	45	theme	serum	1388:1392	arg1	TC					1394:1395	serum TC	1388:1395	serum TC	1388:1395	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	2	46	theme	different	533:541	arg1	dosages					543:549	different dosages	533:549	different dosages of EP (100, 200 and 300 mg kg-1 day-1)	533:588	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	7	47	theme	bile	1373:1376	arg1	acids					1378:1382	fecal conjugated bile acids	1356:1382	fecal conjugated bile acids	1356:1382	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	7	48	theme	bile	1515:1518	arg1	acids					1520:1524	conjugated bile acids	1504:1524	conjugated bile acids	1504:1524	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	2	49	theme	basal	417:421	arg1	diet					423:426	a basal diet	415:426	a basal diet	415:426	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	7	50	theme	Ileibacterium	1313:1325	arg1	correlation					1256:1266	the negative correlation	1243:1266	the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C	1243:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	1	51	from	relationship	277:288	arg1	hypercholesterolemia					248:267	hypercholesterolemia	248:267	hypercholesterolemia	248:267	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	6	52	theme	bile	1192:1195	arg1	acids					1197:1201	fecal conjugated bile acids	1175:1201	fecal conjugated bile acids	1175:1201	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	1	53	from	role	234:237	arg1	hypercholesterolemia					248:267	hypercholesterolemia	248:267	hypercholesterolemia	248:267	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	8	54	theme	above	1555:1559	arg1	findings					1561:1568	the above findings	1551:1568	the above findings	1551:1568	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	2	55	dep	mg	575:576	arg1	day-1					583:587	kg-1 day-1	578:587	kg-1 day-1	578:587	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	4	56	theme	hepatic	855:861	arg1	uptake					875:880	the hepatic cholesterol uptake	851:880	the hepatic cholesterol uptake	851:880	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	5	57	theme	norank_f_	1044:1052	arg1	Muribaculaceae					1054:1067	norank_f_ Muribaculaceae	1044:1067	norank_f_ Muribaculaceae	1044:1067	Apart from that, EP altered the gut microbiota, pre-dominantly increasing microbes associated with bile acid metabolism, such as norank_f_ Muribaculaceae.					
36331041	4	58	theme	EP	787:788	arg1	intervention					790:801	EP intervention	787:801	EP intervention	787:801	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	7	59	theme	negative	1247:1254	arg1	correlation					1256:1266	the negative correlation	1243:1266	the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C	1243:1405	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	4	60	theme	acid	891:894	arg1	pathway					906:912	bile acid synthetic pathway	886:912	bile acid synthetic pathway	886:912	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	3	61	theme	lipoprotein	709:719	arg1	cholesterol					721:731	low-density lipoprotein cholesterol	697:731	low-density lipoprotein cholesterol (LDL-C)	697:739	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	3	61	theme	lipoprotein	709:719	arg1	LDL-C					734:738	LDL-C	734:738	LDL-C	734:738	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	3	62	theme	serum	646:650	arg1	concentrations					652:665	serum concentrations	646:665	serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C)	646:739	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	7	63	theme	conjugated	1504:1513	arg1	acids					1520:1524	conjugated bile acids	1504:1524	conjugated bile acids	1504:1524	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	5	64	theme	bile	1014:1017	arg1	metabolism					1024:1033	bile acid metabolism	1014:1033	bile acid metabolism	1014:1033	Apart from that, EP altered the gut microbiota, pre-dominantly increasing microbes associated with bile acid metabolism, such as norank_f_ Muribaculaceae.					
36331041	6	65	theme	profile	1090:1096	arg1	analysis					1098:1105	bile acid profile analysis	1080:1105	bile acid profile analysis	1080:1105	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	3	66	theme	cholesterol	721:731	arg1	concentrations					652:665	serum concentrations	646:665	serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C)	646:739	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	3	67	theme	EP	622:623	arg1	intervention					625:636	EP intervention	622:636	EP intervention	622:636	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	1	68	with	relationship	277:288	arg1	microbiota					303:312	the gut microbiota	295:312	the gut microbiota	295:312	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	1	69	theme	Enteromorpha	156:167	arg1	EP					180:181	EP	180:181	EP	180:181	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	1	69	theme	Enteromorpha	156:167	arg1	prolifera					169:177	Enteromorpha prolifera	156:177	Enteromorpha prolifera (EP)	156:182	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	8	70	theme	cholesterol	1635:1645	arg1	metabolism					1647:1656	cholesterol metabolism	1635:1656	cholesterol metabolism	1635:1656	To sum up, the above findings revealed that EP may alleviate hypercholesterolemia and regulate cholesterol metabolism in ways that promote a favorable fecal microbiota composition and modulate bile acid metabolism.					
36331041	1	71	theme	EP	242:243	arg1	relationship					277:288	its relationship	273:288	its relationship with the gut microbiota	273:312	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	1	71	theme	EP	242:243	arg1	role					234:237	the role	230:237	the role of EP in hypercholesterolemia	230:267	Polysaccharides from Enteromorpha prolifera (EP) possess multiple biological activities, while the role of EP in hypercholesterolemia and its relationship with the gut microbiota have not been elucidated.					
36331041	2	72	theme	EP	554:555	arg1	dosages					543:549	different dosages	533:549	different dosages of EP (100, 200 and 300 mg kg-1 day-1)	533:588	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36331041	5	73	theme	acid	1019:1022	arg1	metabolism					1024:1033	bile acid metabolism	1014:1033	bile acid metabolism	1014:1033	Apart from that, EP altered the gut microbiota, pre-dominantly increasing microbes associated with bile acid metabolism, such as norank_f_ Muribaculaceae.					
36331041	5	74	theme	gut	947:949	arg1	microbiota					951:960	the gut microbiota	943:960	the gut microbiota	943:960	Apart from that, EP altered the gut microbiota, pre-dominantly increasing microbes associated with bile acid metabolism, such as norank_f_ Muribaculaceae.					
36331041	6	75	theme	bile	1080:1083	arg1	analysis					1098:1105	bile acid profile analysis	1080:1105	bile acid profile analysis	1080:1105	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	3	76	theme	hepatic	755:761	arg1	deposition					775:784	hepatic cholesterol deposition	755:784	hepatic cholesterol deposition	755:784	Here we show that EP intervention lowered serum concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and inhibited hepatic cholesterol deposition.					
36331041	0	77	theme	gut	94:96	arg1	microbiota					98:107	the gut microbiota and bile acid metabolism	90:132	microbiota	98:107	Polysaccharides from Enteromorpha prolifera alleviate hypercholesterolemia via modulating the gut microbiota and bile acid metabolism.					
36331041	4	78	theme	bile	886:889	arg1	pathway					906:912	bile acid synthetic pathway	886:912	bile acid synthetic pathway	886:912	EP intervention also upregulated the gene expression related to the hepatic cholesterol uptake and bile acid synthetic pathway.					
36331041	7	79	theme	correlation	1212:1222	arg1	analysis					1224:1231	Further correlation analysis	1204:1231	Further correlation analysis	1204:1231	Further correlation analysis indicated the negative correlation of Bacteroides, norank_f_ Muribaculaceae and Ileibacterium abundance with the levels of fecal conjugated bile acids and serum TC and LDL-C, while the abundance of Proteobacteria and Lachnoclosteridium showed a positive association with conjugated bile acids and serum TC.					
36331041	0	80	from	prolifera	34:42	arg1	Polysaccharides					0:14	Polysaccharides	0:14	Polysaccharides from Enteromorpha prolifera	0:42	Polysaccharides from Enteromorpha prolifera alleviate hypercholesterolemia via modulating the gut microbiota and bile acid metabolism.					
36331041	6	81	theme	acid	1151:1154	arg1	profile					1156:1162	the fecal bile acid profile	1136:1162	the fecal bile acid profile	1136:1162	Moreover, bile acid profile analysis revealed that EP could alter the fecal bile acid profile and reduce fecal conjugated bile acids.					
36331041	2	82	theme	C57BL/6J	374:381	arg1	mice					383:386	fifty male C57BL/6J mice	363:386	fifty male C57BL/6J mice	363:386	To address this issue, fifty male C57BL/6J mice were randomly subjected to a basal diet and a high-fat and high-cholesterol diet, and 3 treatment groups were fed an HFHC diet supplemented with different dosages of EP (100, 200 and 300 mg kg-1 day-1) for 12 weeks.					
36778266	7	0	theme	powerful	1162:1169	arg1	workflow					1171:1178	a powerful workflow	1160:1178	a powerful workflow to better understand the detailed molecular structures of the mucinome	1160:1249	Overall, we present a powerful workflow to better understand the detailed molecular structures of the mucinome.					
36778266	5	1	theme	TIM	952:954	arg1	family					956:961	the entire TIM family	941:961	the entire TIM family	941:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	1	2	theme	critical	170:177	arg1	roles					179:183	critical roles	170:183	critical roles	170:183	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	2	3	theme	immune	333:338	arg1	cells					340:344	immune cells	333:344	immune cells	333:344	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	5	4	theme	entire	945:950	arg1	family					956:961	the entire TIM family	941:961	the entire TIM family	941:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	6	5	theme	TIM-3	1047:1051	arg1	simulations					1032:1042	molecular dynamics (MD) simulations	1008:1042	molecular dynamics (MD) simulations of TIM-3 and -4	1008:1058	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	2	6	theme	proteins	299:306	arg1	immunoglobulin					246:259	the T cell immunoglobulin and mucin-domain containing family	235:294	immunoglobulin	246:259	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	6	theme	proteins	299:306	arg1	inhibitors					372:381	key checkpoint inhibitors	357:381	key checkpoint inhibitors in cancer	357:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	6	theme	proteins	299:306	arg1	family					289:294	the T cell immunoglobulin and mucin-domain containing family	235:294	family	289:294	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	5	7	theme	mucins	923:928	arg1	analysis					903:910	improved mass spectrometric analysis	875:910	improved mass spectrometric analysis of several mucins, including the entire TIM family	875:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	0	8	theme	mucinase	93:100	arg1	SmE					102:104	mucinase SmE	93:104	mucinase SmE	93:104	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	2	9	dep	proteins	299:306	arg1	TIM-1					309:313	TIM-1	309:313	TIM-1	309:313	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	5	10	theme	spectrometric	889:901	arg1	analysis					903:910	improved mass spectrometric analysis	875:910	improved mass spectrometric analysis of several mucins, including the entire TIM family	875:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	4	11	theme	mucin	682:686	arg1	backbone					701:708	the mucin glycoprotein backbone	678:708	the mucin glycoprotein backbone	678:708	Here, we present a mucinase (SmE) and demonstrate its ability to selectively cleave along the mucin glycoprotein backbone, similar to others of its kind.					
36778266	5	12	theme	unique	790:795	arg1	ability					797:803	the unique ability	786:803	the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family	786:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	4	13	theme	similar	711:717	arg1	backbone					701:708	the mucin glycoprotein backbone	678:708	the mucin glycoprotein backbone	678:708	Here, we present a mucinase (SmE) and demonstrate its ability to selectively cleave along the mucin glycoprotein backbone, similar to others of its kind.					
36778266	4	14	gly	glycoprotein	688:699	arg1	glycoprotein					688:699	the mucin glycoprotein backbone	678:708	the mucin glycoprotein backbone	678:708	Here, we present a mucinase (SmE) and demonstrate its ability to selectively cleave along the mucin glycoprotein backbone, similar to others of its kind.					
36778266	3	15	theme	dense	409:413	arg1	O-glycosylation					415:429	their dense O-glycosylation	403:429	their dense O-glycosylation	403:429	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	6	16	gly	glycosylation	1079:1091	arg1	proteins					1130:1137	these proteins	1124:1137	these proteins	1124:1137	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	2	17	theme	containing	278:287	arg1	family					289:294	the T cell immunoglobulin and mucin-domain containing family	235:294	family	289:294	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	18	theme	checkpoint	361:370	arg1	immunoglobulin					246:259	the T cell immunoglobulin and mucin-domain containing family	235:294	immunoglobulin	246:259	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	18	theme	checkpoint	361:370	arg1	inhibitors					372:381	key checkpoint inhibitors	357:381	key checkpoint inhibitors in cancer	357:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	19	theme	-3	316:317	arg1	TIM-1					309:313	TIM-1	309:313	TIM-1	309:313	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	20	theme	key	357:359	arg1	immunoglobulin					246:259	the T cell immunoglobulin and mucin-domain containing family	235:294	immunoglobulin	246:259	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	20	theme	key	357:359	arg1	inhibitors					372:381	key checkpoint inhibitors	357:381	key checkpoint inhibitors in cancer	357:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	0	21	theme	Glycoproteomic	0:13	arg1	landscape					15:23	Glycoproteomic landscape	0:23	Glycoproteomic landscape	0:23	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	0	22	theme	structural	29:38	arg1	dynamics					40:47	structural dynamics	29:47	structural dynamics	29:47	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	5	23	theme	several	915:921	arg1	mucins					923:928	several mucins	915:928	several mucins	915:928	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	5	23	theme	several	915:921	arg1	family					956:961	the entire TIM family	941:961	the entire TIM family	941:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	1	24	theme	biological	198:207	arg1	functions					209:217	biological functions	198:217	biological functions	198:217	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	1	25	gly	glycoproteins	120:132	arg1	glycoproteins					120:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	1	26	theme	Mucin-domain	107:118	arg1	glycoproteins					120:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	1	27	theme	functions	209:217	arg1	host					190:193	a host	188:193	a host of biological functions	188:217	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	5	28	theme	improved	875:882	arg1	analysis					903:910	improved mass spectrometric analysis	875:910	improved mass spectrometric analysis of several mucins, including the entire TIM family	875:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	1	29	gly	O-glycosylated	146:159	arg1	glycoproteins					120:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins	107:132	Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions.					
36778266	7	30	theme	detailed	1205:1212	arg1	structures					1224:1233	the detailed molecular structures	1201:1233	the detailed molecular structures of the mucinome	1201:1249	Overall, we present a powerful workflow to better understand the detailed molecular structures of the mucinome.					
36778266	2	31	theme	T	239:239	arg1	immunoglobulin					246:259	the T cell immunoglobulin and mucin-domain containing family	235:294	immunoglobulin	246:259	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	31	theme	T	239:239	arg1	inhibitors					372:381	key checkpoint inhibitors	357:381	key checkpoint inhibitors in cancer	357:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	5	32	theme	other	749:753	arg1	mucinases					755:763	other mucinases	749:763	other mucinases	749:763	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	6	33	theme	molecular	1008:1016	arg1	MD					1028:1029	MD	1028:1029	MD	1028:1029	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	6	33	theme	molecular	1008:1016	arg1	dynamics					1018:1025	molecular dynamics	1008:1025	molecular dynamics (MD) simulations of TIM-3 and -4	1008:1058	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	0	34	theme	family	56:61	arg1	checkpoints					70:80	TIM family immune checkpoints	52:80	TIM family immune checkpoints	52:80	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	3	35	theme	mucin	573:577	arg1	domains					579:585	mucin domains	573:585	mucin domains	573:585	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	6	36	theme	-4	1057:1058	arg1	simulations					1032:1042	molecular dynamics (MD) simulations	1008:1042	molecular dynamics (MD) simulations of TIM-3 and -4	1008:1058	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	3	37	theme	glycoproteomic	466:479	arg1	landscape					481:489	glycoproteomic landscape	466:489	glycoproteomic landscape	466:489	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	0	38	theme	TIM	52:54	arg1	checkpoints					70:80	TIM family immune checkpoints	52:80	TIM family immune checkpoints	52:80	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	2	39	from	inhibitors	372:381	arg1	cancer					386:391	cancer	386:391	cancer	386:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	3	40	theme	landscape	481:489	arg1	terms					457:461	terms	457:461	terms of glycoproteomic landscape and structural dynamics	457:513	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	7	41	theme	molecular	1214:1222	arg1	structures					1224:1233	the detailed molecular structures	1201:1233	the detailed molecular structures of the mucinome	1201:1249	Overall, we present a powerful workflow to better understand the detailed molecular structures of the mucinome.					
36778266	3	42	theme	structural	495:504	arg1	dynamics					506:513	structural dynamics	495:513	structural dynamics	495:513	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	2	43	theme	mucin-domain	265:276	arg1	family					289:294	the T cell immunoglobulin and mucin-domain containing family	235:294	family	289:294	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	44	theme	-4	320:321	arg1	TIM-1					309:313	TIM-1	309:313	TIM-1	309:313	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	6	45	theme	structural	1101:1110	arg1	features					1112:1119	structural features	1101:1119	structural features of these proteins	1101:1137	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	4	46	theme	kind	736:739	arg1	others					722:727	others	722:727	others of its kind	722:739	Here, we present a mucinase (SmE) and demonstrate its ability to selectively cleave along the mucin glycoprotein backbone, similar to others of its kind.					
36778266	7	47	theme	mucinome	1242:1249	arg1	structures					1224:1233	the detailed molecular structures	1201:1233	the detailed molecular structures of the mucinome	1201:1249	Overall, we present a powerful workflow to better understand the detailed molecular structures of the mucinome.					
36778266	3	48	dep	enigmatic	439:447	arg1	both					449:452	both	449:452	both	449:452	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	4	49	theme	glycoprotein	688:699	arg1	backbone					701:708	the mucin glycoprotein backbone	678:708	the mucin glycoprotein backbone	678:708	Here, we present a mucinase (SmE) and demonstrate its ability to selectively cleave along the mucin glycoprotein backbone, similar to others of its kind.					
36778266	5	50	theme	mass	884:887	arg1	analysis					903:910	improved mass spectrometric analysis	875:910	improved mass spectrometric analysis of several mucins, including the entire TIM family	875:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36778266	0	51	theme	checkpoints	70:80	arg1	landscape					15:23	Glycoproteomic landscape	0:23	Glycoproteomic landscape	0:23	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	0	51	theme	checkpoints	70:80	arg1	dynamics					40:47	structural dynamics	29:47	structural dynamics	29:47	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	6	52	theme	dynamics	1018:1025	arg1	simulations					1032:1042	molecular dynamics (MD) simulations	1008:1042	molecular dynamics (MD) simulations of TIM-3 and -4	1008:1058	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	3	53	theme	dynamics	506:513	arg1	terms					457:461	terms	457:461	terms of glycoproteomic landscape and structural dynamics	457:513	However, their dense O-glycosylation remains enigmatic both in terms of glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.					
36778266	6	54	theme	proteins	1130:1137	arg1	features					1112:1119	structural features	1101:1119	structural features of these proteins	1101:1137	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	6	55	theme	information	974:984	arg1	in-hand					986:992	this information in-hand	969:992	this information in-hand	969:992	With this information in-hand, we performed molecular dynamics (MD) simulations of TIM-3 and -4 to demonstrate how glycosylation affects structural features of these proteins.					
36778266	0	56	theme	immune	63:68	arg1	checkpoints					70:80	TIM family immune checkpoints	52:80	TIM family immune checkpoints	52:80	Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.					
36778266	2	57	theme	cell	241:244	arg1	immunoglobulin					246:259	the T cell immunoglobulin and mucin-domain containing family	235:294	immunoglobulin	246:259	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	2	57	theme	cell	241:244	arg1	inhibitors					372:381	key checkpoint inhibitors	357:381	key checkpoint inhibitors in cancer	357:391	In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells and act as key checkpoint inhibitors in cancer.					
36778266	5	58	theme	complex	845:851	arg1	glycans					853:859	extremely complex glycans	835:859	extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family	835:961	Unlike other mucinases, though, SmE harbors the unique ability to cleave at residues bearing extremely complex glycans which enabled improved mass spectrometric analysis of several mucins, including the entire TIM family.					
36613923	5	0	theme	wedge	697:701	arg1	"					702:702	"wedge"	696:702	"wedge"	696:702	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	5	1	theme	dynamics	606:613	arg1	simulations					615:625	molecular dynamics simulations	596:625	molecular dynamics simulations	596:625	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	2	theme	potential	305:313	arg1	drugs					324:328	potential antibody drugs	305:328	potential antibody drugs	305:328	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	6	3	theme	antibody	894:901	arg1	antibody					894:901	antibody	894:901	antibody	894:901	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	3	theme	antibody	894:901	arg1	residues					882:889	the key residues	874:889	the key residues of antibody	874:901	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	5	4	theme	"	702:702	arg1	role					688:691	a role	686:691	a role	686:691	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	5	5	theme	simulations	615:625	arg1	results					585:591	the results	581:591	the results of molecular dynamics simulations	581:625	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	5	6	theme	antibody	792:799	arg1	chain					783:787	the heavy chain	773:787	the heavy chain of antibody	773:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	7	theme	target	451:456	arg1	S309					367:370	antibody S309	358:370	antibody S309 from patients with SARS-CoV	358:398	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	7	theme	target	451:456	arg1	antigen					458:464	the target antigen	447:464	the target antigen	447:464	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	5	8	theme	RBD	676:678	arg1	surface					665:671	the surface	661:671	the surface of RBD	661:678	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	9	from	patients	377:384	arg1	S309					367:370	antibody S309	358:370	antibody S309 from patients with SARS-CoV	358:398	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	9	from	patients	377:384	arg1	antigen					458:464	the target antigen	447:464	the target antigen	447:464	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	9	from	patients	377:384	arg1	target					407:412	the target antibody and RBD	403:429	target	407:412	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	8	10	theme	design	1290:1295	arg1	method					1297:1302	the antibody design method	1277:1302	the antibody design method described in this work	1277:1325	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	4	11	with	Systems	467:473	arg1	non-glycosylated					501:516	non-glycosylated	501:516	non-glycosylated	501:516	Systems with RBD glycosylated and non-glycosylated were constructed to study the influence of glycosylation.					
36613923	4	11	with	Systems	467:473	arg1	glycosylated					484:495	glycosylated	484:495	glycosylated	484:495	Systems with RBD glycosylated and non-glycosylated were constructed to study the influence of glycosylation.					
36613923	3	12	theme	high	335:338	arg1	affinity					340:347	high affinity	335:347	high affinity	335:347	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	8	13	theme	drug	1398:1401	arg1	design					1403:1408	antibody drug design	1389:1408	antibody drug design	1389:1408	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	2	14	theme	way	257:259	arg1	way					257:259	the most effective way	238:259	the most effective way of combating SARS-CoV-2	238:283	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	2	14	theme	way	257:259	arg1	one					231:233	one	231:233	one	231:233	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	3	15	theme	S	434:434	arg1	protein					436:442	S protein	434:442	S protein	434:442	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	16	theme	antibody	315:322	arg1	drugs					324:328	potential antibody drugs	305:328	potential antibody drugs	305:328	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	17	theme	protein	436:442	arg1	S309					367:370	antibody S309	358:370	antibody S309 from patients with SARS-CoV	358:398	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	17	theme	protein	436:442	arg1	target					407:412	the target antibody and RBD	403:429	target	407:412	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	17	theme	protein	436:442	arg1	RBD					427:429	RBD	427:429	RBD	427:429	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	6	18	theme	mutants	982:988	arg1	G103A					990:994	G103A	990:994	G103A	990:994	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	18	theme	mutants	982:988	arg1	Y100W					1006:1010	Y100W	1006:1010	Y100W	1006:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	18	theme	mutants	982:988	arg1	affinities					959:968	the binding affinities	947:968	the binding affinities of antibody mutants G103A, P28W and Y100W	947:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	18	theme	mutants	982:988	arg1	stronger					1021:1028	stronger	1021:1028	stronger	1021:1028	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	18	theme	mutants	982:988	arg1	P28W					997:1000	P28W	997:1000	P28W	997:1000	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	2	19	theme	effective	247:255	arg1	way					257:259	the most effective way	238:259	the most effective way of combating SARS-CoV-2	238:283	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	6	20	theme	key	878:880	arg1	antibody					894:901	antibody	894:901	antibody	894:901	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	20	theme	key	878:880	arg1	residues					882:889	the key residues	874:889	the key residues of antibody	874:901	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	3	21	with	patients	377:384	arg1	SARS-CoV					391:398	SARS-CoV	391:398	SARS-CoV	391:398	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	6	22	theme	antibody	973:980	arg1	mutants					982:988	antibody mutants	973:988	antibody mutants	973:988	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	7	23	theme	heavy	1202:1206	arg1	chain					1208:1212	heavy chain	1202:1212	heavy chain	1202:1212	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	5	24	theme	L335-E340	721:729	arg1	region					731:736	the L335-E340 region	717:736	the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody	717:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	7	25	theme	binding	1144:1150	arg1	region					1152:1157	the binding region	1140:1157	the binding region of L335-K356	1140:1170	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	6	26	theme	binding	951:957	arg1	G103A					990:994	G103A	990:994	G103A	990:994	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	26	theme	binding	951:957	arg1	Y100W					1006:1010	Y100W	1006:1010	Y100W	1006:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	26	theme	binding	951:957	arg1	affinities					959:968	the binding affinities	947:968	the binding affinities of antibody mutants G103A, P28W and Y100W	947:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	26	theme	binding	951:957	arg1	stronger					1021:1028	stronger	1021:1028	stronger	1021:1028	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	26	theme	binding	951:957	arg1	P28W					997:1000	P28W	997:1000	P28W	997:1000	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	0	27	theme	High-Affinity	0:12	arg1	Antibodies					14:23	High-Affinity Antibodies	0:23	High-Affinity Antibodies Designing of SARS-CoV-2	0:47	High-Affinity Antibodies Designing of SARS-CoV-2 Based on Molecular Dynamics Simulations.					
36613923	5	28	theme	molecular	596:604	arg1	simulations					615:625	molecular dynamics simulations	596:625	molecular dynamics simulations	596:625	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	8	29	theme	theoretical	1339:1349	arg1	guidance					1351:1358	theoretical guidance	1339:1358	theoretical guidance	1339:1358	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	1	30	theme	tremendous	170:179	arg1	impact					181:186	a tremendous impact	168:186	a tremendous impact	168:186	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	2	31	theme	SARS-CoV-2	274:283	arg1	way					257:259	the most effective way	238:259	the most effective way of combating SARS-CoV-2	238:283	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	0	32	theme	Designing	25:33	arg1	Antibodies					14:23	High-Affinity Antibodies	0:23	High-Affinity Antibodies Designing of SARS-CoV-2	0:47	High-Affinity Antibodies Designing of SARS-CoV-2 Based on Molecular Dynamics Simulations.					
36613923	8	33	theme	antibody	1389:1396	arg1	design					1403:1408	antibody drug design	1389:1408	antibody drug design	1389:1408	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	2	34	theme	combating	264:272	arg1	SARS-CoV-2					274:283	combating SARS-CoV-2	264:283	combating SARS-CoV-2	264:283	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	5	35	theme	chain	783:787	arg1	region					763:768	the CDR3 region	754:768	the CDR3 region of the heavy chain of antibody	754:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	36	used	used	353:356	arg2	we					350:351	we	350:351	we	350:351	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	5	37	theme	heavy	777:781	arg1	chain					783:787	the heavy chain	773:787	the heavy chain of antibody	773:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	7	38	theme	L335-K356	1162:1170	arg1	region					1152:1157	the binding region	1140:1157	the binding region of L335-K356	1140:1170	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	0	39	theme	SARS-CoV-2	38:47	arg1	Designing					25:33	Designing	25:33	Designing	25:33	High-Affinity Antibodies Designing of SARS-CoV-2 Based on Molecular Dynamics Simulations.					
36613923	1	40	contain	had	164:166	arg1	pandemic					121:128	a global pandemic	112:128	a global pandemic	112:128	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	1	40	contain	had	164:166	arg2	impact					181:186	a tremendous impact	168:186	a tremendous impact	168:186	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	2	41	theme	drug	215:218	arg1	therapy					220:226	Antibody drug therapy	206:226	Antibody drug therapy	206:226	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	5	42	theme	CDR3	758:761	arg1	region					763:768	the CDR3 region	754:768	the CDR3 region of the heavy chain of antibody	754:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	43	theme	antibody	358:365	arg1	S309					367:370	antibody S309	358:370	antibody S309 from patients with SARS-CoV	358:398	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	43	theme	antibody	358:365	arg1	antigen					458:464	the target antigen	447:464	the target antigen	447:464	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	3	43	theme	antibody	358:365	arg1	target					407:412	the target antibody and RBD	403:429	target	407:412	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	5	44	theme	steric	632:637	arg1	effects					639:645	the steric effects	628:645	the steric effects of glycans on the surface of RBD	628:678	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	0	45	theme	Dynamics	68:75	arg1	Simulations					77:87	Molecular Dynamics Simulations	58:87	Molecular Dynamics Simulations	58:87	High-Affinity Antibodies Designing of SARS-CoV-2 Based on Molecular Dynamics Simulations.					
36613923	2	46	theme	Antibody	206:213	arg1	therapy					220:226	Antibody drug therapy	206:226	Antibody drug therapy	206:226	Antibody drug therapy is one of the most effective way of combating SARS-CoV-2.					
36613923	1	47	theme	global	114:119	arg1	pandemic					121:128	a global pandemic	112:128	a global pandemic	112:128	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	8	48	theme	time-saving	1366:1376	arg1	method					1378:1383	a time-saving method	1364:1383	a time-saving method for antibody drug design	1364:1408	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	6	49	dep	affinities	959:968	arg1	G103A					990:994	G103A	990:994	G103A	990:994	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	49	dep	affinities	959:968	arg1	affinities					959:968	the binding affinities	947:968	the binding affinities of antibody mutants G103A, P28W and Y100W	947:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	49	dep	affinities	959:968	arg1	Y100W					1006:1010	Y100W	1006:1010	Y100W	1006:1010	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	6	49	dep	affinities	959:968	arg1	P28W					997:1000	P28W	997:1000	P28W	997:1000	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	7	50	theme	structural	1238:1247	arg1	transition					1249:1258	structural transition	1238:1258	structural transition	1238:1258	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	7	51	dep	antigen	1179:1185	arg1	the					1175:1177	the	1175:1177	the	1175:1177	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	6	52	theme	G103A	1077:1081	arg1	mutant					1083:1088	the G103A mutant	1073:1088	the G103A mutant	1073:1088	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	3	53	dep	target	407:412	arg1	antibody					414:421	antibody	414:421	antibody	414:421	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	7	54	from	antigen	1179:1185	arg1	antibody					1221:1228	the antibody	1217:1228	the antibody	1217:1228	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	5	55	theme	contact	819:825	arg1	area					827:830	the contact area	815:830	the contact area between antigen and antibody	815:859	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	4	56	theme	glycosylation	561:573	arg1	influence					548:556	the influence	544:556	the influence of glycosylation	544:573	Systems with RBD glycosylated and non-glycosylated were constructed to study the influence of glycosylation.					
36613923	5	57	theme	glycans	650:656	arg1	effects					639:645	the steric effects	628:645	the steric effects of glycans on the surface of RBD	628:678	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	3	58	dep	design	298:303	arg1	to					295:296	to	295:296	to	295:296	In order to design potential antibody drugs with high affinity, we used antibody S309 from patients with SARS-CoV as the target antibody and RBD of S protein as the target antigen.					
36613923	8	59	theme	antibody	1281:1288	arg1	method					1297:1302	the antibody design method	1277:1302	the antibody design method described in this work	1277:1325	Taken together, the antibody design method described in this work can provide theoretical guidance and a time-saving method for antibody drug design.					
36613923	1	60	theme	new	133:135	arg1	pneumonia					143:151	new crown pneumonia	133:151	new crown pneumonia	133:151	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	6	61	theme	interaction	910:920	arg1	interface					922:930	the interaction interface	906:930	the interaction interface	906:930	By mutating the key residues of antibody at the interaction interface, we found that the binding affinities of antibody mutants G103A, P28W and Y100W were all stronger than that of the wild-type, especially for the G103A mutant.					
36613923	7	62	theme	chain	1208:1212	arg1	P28-Y32					1191:1197	P28-Y32	1191:1197	P28-Y32	1191:1197	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	7	62	theme	chain	1208:1212	arg1	antigen					1179:1185	antigen	1179:1185	antigen	1179:1185	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	7	63	from	P28-Y32	1191:1197	arg1	antibody					1221:1228	the antibody	1217:1228	the antibody	1217:1228	G103A significantly reduces the distance between the binding region of L335-K356 in the antigen and P28-Y32 of heavy chain in the antibody through structural transition.					
36613923	1	64	theme	crown	137:141	arg1	pneumonia					143:151	new crown pneumonia	133:151	new crown pneumonia	133:151	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	0	65	theme	Molecular	58:66	arg1	Simulations					77:87	Molecular Dynamics Simulations	58:87	Molecular Dynamics Simulations	58:87	High-Affinity Antibodies Designing of SARS-CoV-2 Based on Molecular Dynamics Simulations.					
36613923	4	66	dep	glycosylated	484:495	arg1	RBD					480:482	RBD	480:482	RBD	480:482	Systems with RBD glycosylated and non-glycosylated were constructed to study the influence of glycosylation.					
36613923	5	67	theme	RBD	741:743	arg1	region					731:736	the L335-E340 region	717:736	the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody	717:799	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
36613923	1	68	theme	pneumonia	143:151	arg1	pandemic					121:128	a global pandemic	112:128	a global pandemic	112:128	SARS-CoV-2 has led to a global pandemic of new crown pneumonia, which has had a tremendous impact on human society.					
36613923	5	69	from	effects	639:645	arg1	surface					665:671	the surface	661:671	the surface of RBD	661:678	From the results of molecular dynamics simulations, the steric effects of glycans on the surface of RBD plays a role of "wedge", which makes the L335-E340 region of RBD close to the CDR3 region of the heavy chain of antibody and increases the contact area between antigen and antibody.					
37086769	0	0	theme	sensitive	92:100	arg1	sensors					113:119	sensitive bioderived sensors	92:119	sensitive bioderived sensors	92:119	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	4	1	theme	virgin	857:862	arg1	nanoplatelets					867:879	virgin GO nanoplatelets	857:879	virgin GO nanoplatelets	857:879	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	0	2	link	bioderived	102:111	arg1	sensors					113:119	sensitive bioderived sensors	92:119	sensitive bioderived sensors	92:119	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	1	3	theme	nanocrystal	159:169	arg1	NPs					195:197	NPs	195:197	NPs	195:197	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	3	theme	nanocrystal	159:169	arg1	nanoparticles					180:192	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles	134:192	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	5	4	theme	viable	1238:1243	arg1	candidate					1245:1253	a viable candidate	1236:1253	a viable candidate for diabetes breath testing	1236:1281	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	4	5	theme	@	927:927	arg1	NPs					933:935	GO3@CNC3 NPs	924:935	GO3@CNC3 NPs	924:935	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	4	6	dep	nanoplatelets	867:879	arg1	GO					864:865	GO	864:865	GO	864:865	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	4	7	theme	GO3	924:926	arg1	NPs					933:935	GO3@CNC3 NPs	924:935	GO3@CNC3 NPs	924:935	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	0	8	theme	bioderived	102:111	arg1	sensors					113:119	sensitive bioderived sensors	92:119	sensitive bioderived sensors	92:119	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	2	9	theme	chemical	336:343	arg1	characteristics					345:359	chemical characteristics	336:359	chemical characteristics of these materials	336:378	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	1	10	theme	room	239:242	arg1	process					286:292	a room temperature-based simple modified hummers process	237:292	a room temperature-based simple modified hummers process	237:292	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	5	11	theme	breath	1268:1273	arg1	testing					1275:1281	diabetes breath testing	1259:1281	diabetes breath testing	1259:1281	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	5	12	theme	diabetes	1259:1266	arg1	testing					1275:1281	diabetes breath testing	1259:1281	diabetes breath testing	1259:1281	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	4	13	dep	sensor	1027:1032	arg1	GO					1024:1025	GO	1024:1025	GO	1024:1025	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	1	14	theme	GO	172:173	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	14	theme	GO	172:173	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	2	15	theme	other	475:479	arg1	techniques					481:490	other techniques	475:490	other techniques	475:490	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	5	16	theme	sub-ppm	1164:1170	arg1	concentrations					1172:1185	sub-ppm concentrations	1164:1185	sub-ppm concentrations as well as a detection limit of 5 ppm	1164:1223	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	1	17	theme	@	174:174	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	17	theme	@	174:174	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	0	18	theme	metal	15:19	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	3	19	theme	GO1	662:664	arg1	CNC1					666:669	GO1@CNC1	662:669	GO1@CNC1	662:669	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	3	20	theme	@	665:665	arg1	CNC1					666:669	GO1@CNC1	662:669	GO1@CNC1	662:669	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	2	21	theme	morphological	299:311	arg1	structures					313:322	The morphological structures	295:322	The morphological structures	295:322	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	22	theme	materials	370:378	arg1	structures					313:322	The morphological structures	295:322	The morphological structures	295:322	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	22	theme	materials	370:378	arg1	characteristics					345:359	chemical characteristics	336:359	chemical characteristics of these materials	336:378	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	0	23	theme	Supersensitive	0:13	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	1	24	theme	temperature-based	244:260	arg1	process					286:292	a room temperature-based simple modified hummers process	237:292	a room temperature-based simple modified hummers process	237:292	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	25	theme	simple	262:267	arg1	process					286:292	a room temperature-based simple modified hummers process	237:292	a room temperature-based simple modified hummers process	237:292	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	3	26	theme	as-prepared	519:529	arg1	nanoparticles					531:543	the as-prepared nanoparticles	515:543	the as-prepared nanoparticles	515:543	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	4	27	theme	highest	948:954	arg1	higher					993:998	higher	993:998	higher	993:998	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	4	27	theme	highest	948:954	arg1	response					956:963	the highest response	944:963	the highest response (60.88 at 5 ppm)	944:980	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	1	28	theme	nanoparticles	180:192	arg1	series					124:129	A series	122:129	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	122:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	0	29	theme	free	21:24	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	1	30	theme	modified	269:276	arg1	process					286:292	a room temperature-based simple modified hummers process	237:292	a room temperature-based simple modified hummers process	237:292	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	4	31	dep	response	956:963	arg1	5 ppm					975:979	5 ppm	975:979	5 ppm	975:979	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	4	32	dep	GO	760:761	arg1	showed					937:942	showed	937:942	showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported	937:1093	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	2	33	theme	X-ray	446:450	arg1	XRD					465:467	XRD	465:467	XRD	465:467	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	33	theme	X-ray	446:450	arg1	diffraction					452:462	X-ray diffraction	446:462	X-ray diffraction (XRD)	446:468	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	34	theme	transmission	406:417	arg1	TEM					440:442	TEM	440:442	TEM	440:442	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	34	theme	transmission	406:417	arg1	microscopy					428:437	transmission electron microscopy	406:437	transmission electron microscopy (TEM)	406:443	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	0	35	theme	graphene	46:53	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	1	36	theme	hummers	278:284	arg1	process					286:292	a room temperature-based simple modified hummers process	237:292	a room temperature-based simple modified hummers process	237:292	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	4	37	theme	better	793:798	arg1	characteristics					808:822	significantly better sensing characteristics	779:822	significantly better sensing characteristics	779:822	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	3	38	theme	crystallite	560:570	arg1	grains					572:577	crystallite grains	560:577	crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces	560:757	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	0	39	theme	synthesized	34:44	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	3	40	theme	@	675:675	arg1	CNC3					676:679	GO2@CNC3	672:679	GO2@CNC3	672:679	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	5	41	theme	detection	1200:1208	arg1	limit					1210:1214	a detection limit	1198:1214	sub-ppm concentrations as well as a detection limit of 5 ppm	1164:1223	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	3	42	with	grains	572:577	arg1	size					595:598	an average size	584:598	an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces	584:757	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	0	43	theme	@	60:60	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	0	44	theme	oxide	55:59	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	4	45	theme	virgin	1017:1022	arg1	sensor					1027:1032	the virgin GO sensor	1013:1032	the virgin GO sensor	1013:1032	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	5	46	theme	high	1128:1131	arg1	sensitivity					1133:1143	a high sensitivity	1126:1143	a high sensitivity towards acetone	1126:1159	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	4	47	dep	200 °C	1037:1042	arg1	operating					1044:1052	operating	1044:1052	operating temperature	1044:1064	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	4	47	dep	200 °C	1037:1042	arg1	including					1070:1078	including	1070:1078	including those reported	1070:1093	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	3	48	theme	GO2	672:674	arg1	CNC3					676:679	GO2@CNC3	672:679	GO2@CNC3	672:679	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	4	49	theme	CNC	763:765	arg1	NPs					767:769	@CNC NPs	762:769	@CNC NPs	762:769	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	3	50	theme	average	587:593	arg1	size					595:598	an average size	584:598	an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces	584:757	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	5	51	theme	5 ppm	1219:1223	arg1	limit					1210:1214	a detection limit	1198:1214	sub-ppm concentrations as well as a detection limit of 5 ppm	1164:1223	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	5	51	theme	5 ppm	1219:1223	arg1	concentrations					1172:1185	sub-ppm concentrations	1164:1185	sub-ppm concentrations as well as a detection limit of 5 ppm	1164:1223	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	1	52	theme	graphene	134:141	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	52	theme	graphene	134:141	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	4	53	theme	CNC3	928:931	arg1	NPs					933:935	GO3@CNC3 NPs	924:935	GO3@CNC3 NPs	924:935	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	3	54	theme	GO3	686:688	arg1	CNC3					690:693	GO3@CNC3	686:693	GO3@CNC3	686:693	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	4	55	theme	@	762:762	arg1	NPs					767:769	@CNC NPs	762:769	@CNC NPs	762:769	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	1	56	theme	oxide	143:147	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	56	theme	oxide	143:147	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	3	57	theme	OH	713:714	arg1	functionalities					722:736	OH &COOH functionalities	713:736	OH &COOH functionalities	713:736	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	3	58	theme	@	689:689	arg1	CNC3					690:693	GO3@CNC3	686:693	GO3@CNC3	686:693	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	2	59	theme	electron	419:426	arg1	TEM					440:442	TEM	440:442	TEM	440:442	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	2	59	theme	electron	419:426	arg1	microscopy					428:437	transmission electron microscopy	406:437	transmission electron microscopy (TEM)	406:443	The morphological structures, as well as chemical characteristics of these materials were characterized using, transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques.					
37086769	1	60	theme	@	148:148	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	60	theme	@	148:148	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	3	61	theme	&COOH	716:720	arg1	functionalities					722:736	OH &COOH functionalities	713:736	OH &COOH functionalities	713:736	The results show that the as-prepared nanoparticles are made up of crystallite grains with an average size of around 7.82, 14.69, 10.77, 7.82, and 12.51 nm for GO, CNC, GO1@CNC1, GO2@CNC3, and GO3@CNC3 respectively, and OH &COOH functionalities on the NPs' surfaces.					
37086769	0	62	theme	cellulose	61:69	arg1	nanocrystals					71:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals	0:82	Supersensitive metal free in-situ synthesized graphene oxide@cellulose nanocrystals acetone sensitive bioderived sensors.					
37086769	4	63	theme	optimal	900:906	arg1	sensor					908:913	the optimal sensor	896:913	the optimal sensor based on GO3@CNC3 NPs	896:935	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
37086769	5	64	contain	have	1121:1124	arg1	sensors					1113:1119	the sensors	1109:1119	the sensors	1109:1119	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	5	64	contain	have	1121:1124	arg2	sensitivity					1133:1143	a high sensitivity	1126:1143	a high sensitivity towards acetone	1126:1159	Furthermore, the sensors have a high sensitivity towards acetone in sub-ppm concentrations as well as a detection limit of 5 ppm, making it a viable candidate for diabetes breath testing.					
37086769	1	65	theme	cellulose	149:157	arg1	CNC					175:177	GO@CNC	172:177	GO@CNC	172:177	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	1	65	theme	cellulose	149:157	arg1	nanocrystal					159:169	graphene oxide@cellulose nanocrystal	134:169	graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs)	134:198	A series of graphene oxide@cellulose nanocrystal (GO@CNC) nanoparticles (NPs) were synthesized in this study using a room temperature-based simple modified hummers process.					
37086769	4	66	theme	sensing	800:806	arg1	characteristics					808:822	significantly better sensing characteristics	779:822	significantly better sensing characteristics	779:822	GO@CNC NPs exhibit significantly better sensing characteristics towards acetone when compared to virgin GO nanoplatelets; specifically, the optimal sensor based on GO3@CNC3 NPs showed the highest response (60.88 at 5 ppm), which was higher than that of the virgin GO sensor at 200 °C operating temperature and including those reported.					
36801223	1	0	theme	living	302:307	arg1	organisms					309:317	living organisms	302:317	living organisms	302:317	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	4	1	theme	FTIR	715:718	arg1	spectrum					720:727	the FTIR spectrum	711:727	the FTIR spectrum	711:727	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	11	2	theme	chelating	1557:1565	arg1	substrate					1567:1575	The CMCh-CFP chelating substrate	1544:1575	The CMCh-CFP chelating substrate	1544:1575	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	12	3	dep	dyes	1750:1753	arg1	reusability					1768:1778	reusability	1768:1778	reusability	1768:1778	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	12	3	dep	dyes	1750:1753	arg1	remediation					1755:1765	remediation	1755:1765	remediation	1755:1765	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	12	3	dep	dyes	1750:1753	arg1	biocompatibility					1784:1799	biocompatibility	1784:1799	biocompatibility	1784:1799	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	12	3	dep	dyes	1750:1753	arg1	dyes					1750:1753	dyes remediation, reusability and biocompatibility	1750:1799	dyes remediation, reusability and biocompatibility	1750:1799	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	3	4	theme	characterization	654:669	arg1	techniques					671:680	various characterization techniques	646:680	various characterization techniques	646:680	To improve solubility, metal adsorption and water decontamination, chitosan were modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.					
36801223	9	5	theme	0.9832	1332:1337	arg1	value					1323:1327	R2 value	1320:1327	R2 value of 0.9832 and 0.969	1320:1347	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	0	6	theme	Comparative	0:10	arg1	robustness					12:21	Comparative robustness	0:21	Comparative robustness	0:21	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	1	7	theme	natural	222:228	arg1	assets					230:235	industrialization natural assets	204:235	industrialization natural assets	204:235	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	9	8	theme	0.969	1343:1347	arg1	value					1323:1327	R2 value	1320:1327	R2 value of 0.9832 and 0.969	1320:1347	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	2	9	theme	sustainable	352:362	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	9	theme	sustainable	352:362	arg1	composite					364:372	robust and sustainable composite	341:372	robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	341:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	8	10	theme	potential	1138:1146	arg1	effectiveness					1148:1160	The potential effectiveness	1134:1160	The potential effectiveness of chitosan matrix	1134:1179	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	4	11	theme	group	767:771	arg1	substitution					737:748	substitution	737:748	substitution of carboxymethyl group in the chitosan	737:787	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	5	12	theme	proton	843:848	arg1	peaks					850:854	the characteristic proton peaks	824:854	the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm	824:897	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	2	13	theme	robust	341:346	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	13	theme	robust	341:346	arg1	composite					364:372	robust and sustainable composite	341:372	robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	341:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	14	theme	current	327:333	arg1	study					335:339	the current study	323:339	the current study	323:339	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	9	15	theme	0.0977	1373:1378	arg1	rate					1365:1368	a constant rate	1354:1368	a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1354:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	11	16	theme	cycles	1634:1639	arg1	batches					1623:1629	4th batches	1619:1629	4th batches of cycles	1619:1639	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	9	17	theme	0.2534 ml/min	1384:1396	arg1	rate					1365:1368	a constant rate	1354:1368	a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1354:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	7	18	theme	XRD	1120:1122	arg1	analysis					1124:1131	FTIR and XRD analysis	1111:1131	FTIR and XRD analysis	1111:1131	The antimony (Sb) loaded modified chitosan were confirmed by FTIR and XRD analysis.					
36801223	0	19	from	chitosan	128:135	arg1	perspective					166:176	environmental remediation perspective	140:176	environmental remediation perspective	140:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	4	20	from	substitution	737:748	arg1	chitosan					780:787	the chitosan	776:787	the chitosan	776:787	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	7	21	theme	FTIR	1111:1114	arg1	analysis					1124:1131	FTIR and XRD analysis	1111:1131	FTIR and XRD analysis	1111:1131	The antimony (Sb) loaded modified chitosan were confirmed by FTIR and XRD analysis.					
36801223	1	22	theme	rapid	190:194	arg1	race					196:199	the rapid race	186:199	the rapid race of industrialization natural assets like fresh water	186:252	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	4	23	theme	characteristic	687:700	arg1	bands					702:706	The characteristic bands	683:706	The characteristic bands in the FTIR spectrum	683:727	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	0	24	theme	chitosan/synthesized	93:112	arg1	chitosan					128:135	chitosan/synthesized carboxymethyl chitosan	93:135	chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective	93:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	2	25	from	composite	364:372	arg1	matrix					460:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	11	26	theme	<4 	1646:1648	arg1	%					1649:1649	%	1649:1649	%	1649:1649	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	5	27	located	observed	864:871	arg1	4.192 ppm					889:897	4.192 ppm	889:897	4.192 ppm	889:897	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	5	27	located	observed	864:871	arg2	CMCh					859:862	CMCh	859:862	CMCh observed at δ = 4.097 to 4.192 ppm	859:897	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	9	28	theme	carboxymethyl	1425:1437	arg1	chitosan					1439:1446	carboxymethyl chitosan	1425:1446	carboxymethyl chitosan respectively	1425:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	8	29	theme	matrix	1174:1179	arg1	effectiveness					1148:1160	The potential effectiveness	1134:1160	The potential effectiveness of chitosan matrix	1134:1179	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	0	30	theme	environmental	140:152	arg1	perspective					166:176	environmental remediation perspective	140:176	environmental remediation perspective	140:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	0	31	theme	in-situ	45:51	arg1	nanoarchitectonics					71:88	in-situ prepared antimony nanoarchitectonics	45:88	in-situ prepared antimony nanoarchitectonics	45:88	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	11	32	from	decrease	1651:1658	arg1	efficiency					1663:1672	efficiency	1663:1672	efficiency	1663:1672	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	3	33	theme	metal	508:512	arg1	adsorption					514:523	metal adsorption	508:523	metal adsorption	508:523	To improve solubility, metal adsorption and water decontamination, chitosan were modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.					
36801223	5	34	theme	1H	948:949	arg1	NMR					951:953	1H NMR	948:953	1H NMR	948:953	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	8	35	theme	reductive	1216:1224	arg1	removal					1226:1232	reductive removal	1216:1232	reductive removal of the Rhodamine b dye	1216:1255	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	6	36	theme	potentiometric	987:1000	arg1	analysis					1002:1009	potentiometric analysis	987:1009	potentiometric analysis	987:1009	The second order derivative of potentiometric analysis confirmed 0.83 degree of substitution.					
36801223	0	37	theme	nanoarchitectonics	71:88	arg1	sustainability					27:40	sustainability	27:40	sustainability	27:40	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	0	37	theme	nanoarchitectonics	71:88	arg1	robustness					12:21	Comparative robustness	0:21	Comparative robustness	0:21	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	9	38	theme	b	1268:1268	arg1	mitigation					1270:1279	Rhodamine b mitigation	1258:1279	Rhodamine b mitigation	1258:1279	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	3	39	theme	carboxymethyl	580:592	arg1	chitosan					594:601	carboxymethyl chitosan	580:601	carboxymethyl chitosan	580:601	To improve solubility, metal adsorption and water decontamination, chitosan were modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.					
36801223	5	40	theme	chitosan	936:943	arg1	methylation					921:931	O-carboxy methylation	911:931	O-carboxy methylation of chitosan by 1H NMR	911:953	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	8	41	theme	Rhodamine	1241:1249	arg1	dye					1253:1255	the Rhodamine b dye	1237:1255	the Rhodamine b dye	1237:1255	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	2	42	theme	in-situ	377:383	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	8	43	theme	dye	1253:1255	arg1	removal					1226:1232	reductive removal	1216:1232	reductive removal of the Rhodamine b dye	1216:1255	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	6	44	theme	second	960:965	arg1	derivative					973:982	The second order derivative	956:982	The second order derivative of potentiometric analysis	956:1009	The second order derivative of potentiometric analysis confirmed 0.83 degree of substitution.					
36801223	9	45	theme	first	1294:1298	arg1	kinetics					1306:1313	first order kinetics	1294:1313	first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1294:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	2	46	theme	chitosan	451:458	arg1	matrix					460:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	1	47	theme	lethal	284:289	arg1	effects					291:297	lethal effects	284:297	lethal effects	284:297	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	2	48	theme	chitosan/synthesized	416:435	arg1	matrix					460:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	11	49	theme	CMCh-CFP	1548:1555	arg1	substrate					1567:1575	The CMCh-CFP chelating substrate	1544:1575	The CMCh-CFP chelating substrate	1544:1575	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	9	50	theme	R2	1320:1321	arg1	value					1323:1327	R2 value	1320:1327	R2 value of 0.9832 and 0.969	1320:1347	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	3	51	theme	various	646:652	arg1	techniques					671:680	various characterization techniques	646:680	various characterization techniques	646:680	To improve solubility, metal adsorption and water decontamination, chitosan were modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.					
36801223	6	52	theme	substitution	1036:1047	arg1	degree					1026:1031	0.83 degree	1021:1031	0.83 degree of substitution	1021:1047	The second order derivative of potentiometric analysis confirmed 0.83 degree of substitution.					
36801223	2	53	from	nanoarchitectonics	394:411	arg1	matrix					460:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	54	theme	nanoarchitectonics	394:411	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	54	theme	nanoarchitectonics	394:411	arg1	composite					364:372	robust and sustainable composite	341:372	robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	341:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	10	55	theme	mitigation	1507:1516	arg1	efficiency					1518:1527	98.5 % mitigation efficiency	1500:1527	98.5 % mitigation efficiency	1500:1527	The Sb/CMCh-CFP enables us to achieve 98.5 % mitigation efficiency within 10 min.					
36801223	1	56	theme	industrialization	204:220	arg1	assets					230:235	industrialization natural assets	204:235	industrialization natural assets	204:235	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	0	57	theme	prepared	53:60	arg1	nanoarchitectonics					71:88	in-situ prepared antimony nanoarchitectonics	45:88	in-situ prepared antimony nanoarchitectonics	45:88	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	1	58	theme	assets	230:235	arg1	race					196:199	the rapid race	186:199	the rapid race of industrialization natural assets like fresh water	186:252	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	5	59	theme	characteristic	828:841	arg1	peaks					850:854	the characteristic proton peaks	824:854	the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm	824:897	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	12	60	located	found	1712:1716	arg1	terms					1741:1745	terms	1741:1745	terms of dyes remediation, reusability and biocompatibility	1741:1799	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	12	60	located	found	1712:1716	arg2	material					1699:1706	The in-situ synthesized material	1675:1706	The in-situ synthesized material	1675:1706	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	1	61	theme	fresh	242:246	arg1	water					248:252	fresh water	242:252	fresh water	242:252	Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms.					
36801223	12	62	theme	dyes	1750:1753	arg1	terms					1741:1745	terms	1741:1745	terms of dyes remediation, reusability and biocompatibility	1741:1799	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	4	63	theme	carboxymethyl	753:765	arg1	group					767:771	carboxymethyl group	753:771	carboxymethyl group	753:771	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	9	64	theme	constant	1356:1363	arg1	rate					1365:1368	a constant rate	1354:1368	a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1354:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	12	65	theme	tailored	1718:1725	arg1	composite					1727:1735	tailored composite	1718:1735	tailored composite	1718:1735	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	5	66	dep	4.192 ppm	889:897	arg1	to					886:887	to	886:887	to	886:887	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	12	67	theme	synthesized	1687:1697	arg1	material					1699:1706	The in-situ synthesized material	1675:1706	The in-situ synthesized material	1675:1706	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	11	68	theme	4th	1619:1621	arg1	batches					1623:1629	4th batches	1619:1629	4th batches of cycles	1619:1639	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	0	69	from	sustainability	27:40	arg1	chitosan					128:135	chitosan/synthesized carboxymethyl chitosan	93:135	chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective	93:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	11	70	theme	%	1649:1649	arg1	decrease					1651:1658	<4 % decrease	1646:1658	<4 % decrease in efficiency	1646:1672	The CMCh-CFP chelating substrate was found stable and efficient even after 4th batches of cycles with <4 % decrease in efficiency.					
36801223	0	71	theme	carboxymethyl	114:126	arg1	chitosan					128:135	chitosan/synthesized carboxymethyl chitosan	93:135	chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective	93:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	9	72	theme	loaded	1405:1410	arg1	chitosan					1412:1419	loaded chitosan	1405:1419	loaded chitosan	1405:1419	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	8	73	theme	chitosan	1165:1172	arg1	matrix					1174:1179	chitosan matrix	1165:1179	chitosan matrix	1165:1179	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	0	74	from	robustness	12:21	arg1	chitosan					128:135	chitosan/synthesized carboxymethyl chitosan	93:135	chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective	93:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	5	75	theme	CMCh	859:862	arg1	peaks					850:854	the characteristic proton peaks	824:854	the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm	824:897	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	0	76	theme	remediation	154:164	arg1	perspective					166:176	environmental remediation perspective	140:176	environmental remediation perspective	140:176	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	3	77	theme	water	529:533	arg1	decontamination					535:549	water decontamination	529:549	water decontamination	529:549	To improve solubility, metal adsorption and water decontamination, chitosan were modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.					
36801223	7	78	theme	modified	1075:1082	arg1	chitosan					1084:1091	modified chitosan	1075:1091	modified chitosan	1075:1091	The antimony (Sb) loaded modified chitosan were confirmed by FTIR and XRD analysis.					
36801223	10	79	theme	98.5 	1500:1504	arg1	%					1505:1505	%	1505:1505	%	1505:1505	The Sb/CMCh-CFP enables us to achieve 98.5 % mitigation efficiency within 10 min.					
36801223	9	80	dep	Sb	1402:1403	arg1	chitosan					1412:1419	loaded chitosan	1405:1419	loaded chitosan	1405:1419	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	5	81	theme	O-carboxy	911:919	arg1	methylation					921:931	O-carboxy methylation	911:931	O-carboxy methylation of chitosan by 1H NMR	911:953	This was further illustrated that the characteristic proton peaks of CMCh observed at δ = 4.097 to 4.192 ppm, suggesting O-carboxy methylation of chitosan by 1H NMR.					
36801223	6	82	theme	analysis	1002:1009	arg1	derivative					973:982	The second order derivative	956:982	The second order derivative of potentiometric analysis	956:1009	The second order derivative of potentiometric analysis confirmed 0.83 degree of substitution.					
36801223	9	83	theme	Rhodamine	1258:1266	arg1	b					1268:1268	Rhodamine b	1258:1268	Rhodamine b mitigation	1258:1279	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	4	84	from	bands	702:706	arg1	spectrum					720:727	the FTIR spectrum	711:727	the FTIR spectrum	711:727	The characteristic bands in the FTIR spectrum confirm substitution of carboxymethyl group in the chitosan.					
36801223	0	85	theme	antimony	62:69	arg1	nanoarchitectonics					71:88	in-situ prepared antimony nanoarchitectonics	45:88	in-situ prepared antimony nanoarchitectonics	45:88	Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.					
36801223	8	86	theme	b	1251:1251	arg1	dye					1253:1255	the Rhodamine b dye	1237:1255	the Rhodamine b dye	1237:1255	The potential effectiveness of chitosan matrix was determined and compared toward reductive removal of the Rhodamine b dye.					
36801223	2	87	from	matrix	460:465	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	87	from	matrix	460:465	arg1	composite					364:372	robust and sustainable composite	341:372	robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	341:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	2	88	theme	antimony	385:392	arg1	nanoarchitectonics					394:411	in-situ antimony nanoarchitectonics	377:411	in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix	377:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
36801223	6	89	theme	order	967:971	arg1	derivative					973:982	The second order derivative	956:982	The second order derivative of potentiometric analysis	956:1009	The second order derivative of potentiometric analysis confirmed 0.83 degree of substitution.					
36801223	12	90	dep	synthesized	1687:1697	arg1	in-situ					1679:1685	in-situ	1679:1685	in-situ	1679:1685	The in-situ synthesized material was found tailored composite, in terms of dyes remediation, reusability and biocompatibility as compared to chitosan.					
36801223	10	91	theme	%	1505:1505	arg1	efficiency					1518:1527	98.5 % mitigation efficiency	1500:1527	98.5 % mitigation efficiency	1500:1527	The Sb/CMCh-CFP enables us to achieve 98.5 % mitigation efficiency within 10 min.					
36801223	9	92	with	kinetics	1306:1313	arg1	rate					1365:1368	a constant rate	1354:1368	a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1354:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	9	92	with	kinetics	1306:1313	arg1	value					1323:1327	R2 value	1320:1327	R2 value of 0.9832 and 0.969	1320:1347	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	9	93	theme	order	1300:1304	arg1	kinetics					1306:1313	first order kinetics	1294:1313	first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively	1294:1459	Rhodamine b mitigation is following first order kinetics with R2 value of 0.9832 and 0.969 with a constant rate of 0.0977 and 0.2534 ml/min for Sb loaded chitosan and carboxymethyl chitosan respectively.					
36801223	2	94	theme	carboxymethyl	437:449	arg1	matrix					460:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	chitosan/synthesized carboxymethyl chitosan matrix	416:465	In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized.					
35834434	3	0	theme	CTS-ECM	307:313	arg1	scaffold					315:322	This CTS-ECM scaffold	302:322	This CTS-ECM scaffold	302:322	This CTS-ECM scaffold can improve cell adhesion and proliferation.					
35834434	4	1	theme	ECM	476:478	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	proportion					557:566	proportion	557:566	proportion of nitrogen element	557:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	indicators					618:627	indicators	618:627	indicators	618:627	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	1	theme	ECM	476:478	arg1	factors					548:554	factors	548:554	factors	548:554	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	0	2	theme	hepatocyte	87:96	arg1	culture					98:104	C3A hepatocyte culture	83:104	C3A hepatocyte culture	83:104	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	4	3	theme	EDC	495:497	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	proportion					557:566	proportion	557:566	proportion of nitrogen element	557:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	indicators					618:627	indicators	618:627	indicators	618:627	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	3	theme	EDC	495:497	arg1	factors					548:554	factors	548:554	factors	548:554	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	6	4	theme	optimal	759:765	arg1	scaffold					767:774	the optimal scaffold	755:774	the optimal scaffold	755:774	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	5	theme	ECM	795:797	arg1	concentration					799:811	ECM concentration	795:811	ECM concentration of 5 mg/mL	795:822	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	6	theme	EDC	825:827	arg1	concentration					829:841	EDC concentration	825:841	EDC concentration of 5 mg/mL	825:852	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	8	7	theme	culture	1124:1130	arg1	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	7	theme	culture	1124:1130	arg1	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	6	8	theme	NHS	866:868	arg1	1:1					876:878	NHS ratio 1:1	866:878	NHS ratio 1:1	866:878	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	8	9	used	used	1093:1096	arg2	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	9	used	used	1093:1096	arg2	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	7	10	theme	C3A	881:883	arg1	hepatocytes					885:895	C3A hepatocytes	881:895	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds	881:939	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	8	11	theme	hepatocyte	1113:1122	arg1	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	11	theme	hepatocyte	1113:1122	arg1	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	4	12	theme	orthogonal	394:403	arg1	test					405:408	an orthogonal test	391:408	an orthogonal test	391:408	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	7	13	theme	optimized	913:921	arg1	scaffolds					931:939	the optimized CTS-ECM scaffolds	909:939	the optimized CTS-ECM scaffolds	909:939	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	4	14	dep	ratio	528:532	arg1	to					521:522	to	521:522	to	521:522	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	1	15	from	part	143:146	arg1	device					171:176	bioartificial liver device	151:176	bioartificial liver device	151:176	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	2	16	dep	matrix	261:266	arg1	fabrics					293:299	fabrics	293:299	fabrics	293:299	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	7	17	theme	<i>p</i>	1027:1034	arg1	microcarriers					1012:1024	Cytodex3 microcarriers	1003:1024	Cytodex3 microcarriers (<i>p</i> &lt; 0.05)	1003:1045	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	7	17	theme	<i>p</i>	1027:1034	arg1	&lt					1036:1038	<i>p</i> &lt; 0.05	1027:1044	<i>p</i> &lt; 0.05	1027:1044	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	6	18	theme	ratio	870:874	arg1	1:1					876:878	NHS ratio 1:1	866:878	NHS ratio 1:1	866:878	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	4	19	theme	present	376:382	arg1	study					384:388	the present study	372:388	the present study	372:388	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	1	20	theme	Hepatocyte	107:116	arg1	part					143:146	an essential part	130:146	an essential part in bioartificial liver device	130:176	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	1	20	theme	Hepatocyte	107:116	arg1	scaffold					118:125	Hepatocyte scaffold	107:125	Hepatocyte scaffold	107:125	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	8	21	theme	promising	1103:1111	arg1	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	21	theme	promising	1103:1111	arg1	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	0	22	theme	liver	31:35	arg1	Optimization					0:11	Optimization	0:11	Optimization of decellularized liver	0:35	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	4	23	theme	NHS	524:526	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	proportion					557:566	proportion	557:566	proportion of nitrogen element	557:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	indicators					618:627	indicators	618:627	indicators	618:627	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	23	theme	NHS	524:526	arg1	factors					548:554	factors	548:554	factors	548:554	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	5	24	theme	C3A	678:680	arg1	hepatocytes					682:692	C3A hepatocytes	678:692	C3A hepatocytes	678:692	The cytocompatibility of the novel scaffold for C3A hepatocytes was analyzed in vitro.					
35834434	8	25	theme	liver	1169:1173	arg1	systems					1183:1189	bioartificial liver support systems	1155:1189	bioartificial liver support systems	1155:1189	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	7	26	theme	CTS-ECM	923:929	arg1	scaffolds					931:939	the optimized CTS-ECM scaffolds	909:939	the optimized CTS-ECM scaffolds	909:939	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	0	27	theme	decellularized	16:29	arg1	liver					31:35	decellularized liver	16:35	decellularized liver	16:35	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	6	28	theme	5 mg/mL	846:852	arg1	EDC					859:861	EDC	859:861	EDC to NHS ratio 1:1	859:878	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	28	theme	5 mg/mL	846:852	arg1	concentration					829:841	EDC concentration	825:841	EDC concentration of 5 mg/mL	825:852	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	28	theme	5 mg/mL	846:852	arg1	concentration					799:811	ECM concentration	795:811	ECM concentration of 5 mg/mL	795:822	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	4	29	theme	hydroxyproline	592:605	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	29	theme	hydroxyproline	592:605	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	29	theme	hydroxyproline	592:605	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	29	theme	hydroxyproline	592:605	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	0	30	theme	chitosan	53:60	arg1	scaffold					70:77	chitosan fibrous scaffold	53:77	chitosan fibrous scaffold for C3A hepatocyte culture	53:104	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	8	31	theme	composite	1060:1068	arg1	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	31	theme	composite	1060:1068	arg1	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	2	32	theme	extracellular	247:259	arg1	ECM					269:271	ECM	269:271	ECM	269:271	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	2	32	theme	extracellular	247:259	arg1	matrix					261:266	porcine liver extracellular matrix	233:266	porcine liver extracellular matrix (ECM)	233:272	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	8	33	theme	support	1175:1181	arg1	systems					1183:1189	bioartificial liver support systems	1155:1189	bioartificial liver support systems	1155:1189	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	34	theme	CTS/ECM	1052:1058	arg1	carrier					1132:1138	a promising hepatocyte culture carrier	1101:1138	a promising hepatocyte culture carrier	1101:1138	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	8	34	theme	CTS/ECM	1052:1058	arg1	scaffold					1070:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold	1048:1077	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	4	35	theme	composite	447:455	arg1	scaffold					457:464	the CTS/ECM composite scaffold	435:464	the CTS/ECM composite scaffold	435:464	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	2	36	theme	liver	241:245	arg1	ECM					269:271	ECM	269:271	ECM	269:271	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	2	36	theme	liver	241:245	arg1	matrix					261:266	porcine liver extracellular matrix	233:266	porcine liver extracellular matrix (ECM)	233:272	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	3	37	dep	cell	336:339	arg1	adhesion					341:348	adhesion	341:348	adhesion	341:348	This CTS-ECM scaffold can improve cell adhesion and proliferation.					
35834434	4	38	theme	CTS/ECM	439:445	arg1	scaffold					457:464	the CTS/ECM composite scaffold	435:464	the CTS/ECM composite scaffold	435:464	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	2	39	theme	porcine	233:239	arg1	ECM					269:271	ECM	269:271	ECM	269:271	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	2	39	theme	porcine	233:239	arg1	matrix					261:266	porcine liver extracellular matrix	233:266	porcine liver extracellular matrix (ECM)	233:272	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	7	40	theme	Cytodex3	1003:1010	arg1	microcarriers					1012:1024	Cytodex3 microcarriers	1003:1024	Cytodex3 microcarriers (<i>p</i> &lt; 0.05)	1003:1045	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	7	40	theme	Cytodex3	1003:1010	arg1	&lt					1036:1038	<i>p</i> &lt; 0.05	1027:1044	<i>p</i> &lt; 0.05	1027:1044	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	0	41	theme	fibrous	62:68	arg1	scaffold					70:77	chitosan fibrous scaffold	53:77	chitosan fibrous scaffold for C3A hepatocyte culture	53:104	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	5	42	theme	novel	659:663	arg1	scaffold					665:672	the novel scaffold	655:672	the novel scaffold for C3A hepatocytes	655:692	The cytocompatibility of the novel scaffold for C3A hepatocytes was analyzed in vitro.					
35834434	1	43	theme	essential	133:141	arg1	part					143:146	an essential part	130:146	an essential part in bioartificial liver device	130:176	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	1	43	theme	essential	133:141	arg1	scaffold					118:125	Hepatocyte scaffold	107:125	Hepatocyte scaffold	107:125	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	4	44	theme	EDC	517:519	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	proportion					557:566	proportion	557:566	proportion of nitrogen element	557:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	indicators					618:627	indicators	618:627	indicators	618:627	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	44	theme	EDC	517:519	arg1	factors					548:554	factors	548:554	factors	548:554	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	5	45	theme	scaffold	665:672	arg1	cytocompatibility					634:650	The cytocompatibility	630:650	The cytocompatibility of the novel scaffold for C3A hepatocytes	630:692	The cytocompatibility of the novel scaffold for C3A hepatocytes was analyzed in vitro.					
35834434	6	46	theme	5 mg/mL	816:822	arg1	EDC					859:861	EDC	859:861	EDC to NHS ratio 1:1	859:878	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	46	theme	5 mg/mL	816:822	arg1	concentration					829:841	EDC concentration	825:841	EDC concentration of 5 mg/mL	825:852	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	46	theme	5 mg/mL	816:822	arg1	concentration					799:811	ECM concentration	795:811	ECM concentration of 5 mg/mL	795:822	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	6	47	theme	orthogonal	721:730	arg1	test					732:735	The orthogonal test	717:735	The orthogonal test	717:735	The orthogonal test demonstrated that the optimal scaffold should be based on ECM concentration of 5 mg/mL, EDC concentration of 5 mg/mL, and EDC to NHS ratio 1:1.					
35834434	4	48	theme	nitrogen	571:578	arg1	element					580:586	nitrogen element	571:586	nitrogen element	571:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	2	49	theme	hepatocyte	204:213	arg1	scaffold					215:222	a novel hepatocyte scaffold	196:222	a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics	196:299	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	7	50	dep	stronger	948:955	arg1	proliferation					957:969	proliferation	957:969	proliferation	957:969	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	7	50	dep	stronger	948:955	arg1	functionality					975:987	functionality	975:987	functionality	975:987	C3A hepatocytes cultured on the optimized CTS-ECM scaffolds showed stronger proliferation and functionality than those on Cytodex3 microcarriers (<i>p</i> &lt; 0.05).					
35834434	0	51	theme	C3A	83:85	arg1	culture					98:104	C3A hepatocyte culture	83:104	C3A hepatocyte culture	83:104	Optimization of decellularized liver matrix-modified chitosan fibrous scaffold for C3A hepatocyte culture.					
35834434	2	52	theme	novel	198:202	arg1	scaffold					215:222	a novel hepatocyte scaffold	196:222	a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics	196:299	We have designed a novel hepatocyte scaffold based on porcine liver extracellular matrix (ECM) and chitosan (CTS) fabrics.					
35834434	1	53	theme	bioartificial	151:163	arg1	device					171:176	bioartificial liver device	151:176	bioartificial liver device	151:176	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	8	54	theme	bioartificial	1155:1167	arg1	systems					1183:1189	bioartificial liver support systems	1155:1189	bioartificial liver support systems	1155:1189	The CTS/ECM composite scaffold may be widely used as a promising hepatocyte culture carrier, especially in bioartificial liver support systems.					
35834434	1	55	theme	liver	165:169	arg1	device					171:176	bioartificial liver device	151:176	bioartificial liver device	151:176	Hepatocyte scaffold is an essential part in bioartificial liver device.					
35834434	4	56	theme	element	580:586	arg1	concentration					480:492	ECM concentration	476:492	ECM concentration	476:492	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	56	theme	element	580:586	arg1	proportion					557:566	proportion	557:566	proportion of nitrogen element	557:586	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	56	theme	element	580:586	arg1	content					607:613	hydroxyproline content	592:613	hydroxyproline content	592:613	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	56	theme	element	580:586	arg1	ratio					528:532	EDC to NHS ratio	517:532	EDC to NHS ratio	517:532	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	56	theme	element	580:586	arg1	concentration					499:511	EDC concentration	495:511	EDC concentration	495:511	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35834434	4	56	theme	element	580:586	arg1	factors					548:554	factors	548:554	factors	548:554	In the present study, an orthogonal test was designed to optimize the CTS/ECM composite scaffold, in which ECM concentration, EDC concentration and EDC to NHS ratio were taken as factors, proportion of nitrogen element and hydroxyproline content as indicators.					
35344341	5	0	contain	containing	1101:1110	arg2	structure					1140:1148	the shear-induced assembled structure	1112:1148	the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1112:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	5	0	contain	containing	1101:1110	arg1	domains					1093:1099	the anisotropic domains	1077:1099	the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1077:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	2	1	theme	suspensions	355:365	arg1	process					330:336	the drying process	319:336	the drying process of CNC/PEG mixed suspensions	319:365	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	1	2	from	influence	96:104	arg1	properties					142:151	the nanomechanical properties	123:151	the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	123:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	3	theme	anisotropic	250:260	arg1	phases					262:267	anisotropic phases	250:267	anisotropic phases	250:267	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	4	4	with	comparison	703:712	arg1	films					773:777	nonsheared films	762:777	nonsheared films	762:777	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	5	theme	CNC	179:181	arg1	glycol					197:202	cellulose nanocrystal (CNC)/polyethylene glycol	156:202	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	5	theme	CNC	179:181	arg1	PEG					205:207	PEG	205:207	PEG	205:207	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	6	theme	phases	262:267	arg1	distribution					234:245	the distribution	230:245	the distribution of anisotropic phases	230:267	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	6	theme	phases	262:267	arg1	influence					96:104	The influence	92:104	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	92:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	3	7	theme	shear	689:693	arg1	flow					695:698	shear flow	689:698	shear flow	689:698	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	8	theme	CNC/PEG	545:551	arg1	films					553:557	CNC/PEG films	545:557	CNC/PEG films	545:557	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	9	theme	polarized	562:570	arg1	POM					592:594	POM	592:594	POM	592:594	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	9	theme	polarized	562:570	arg1	microscopy					580:589	polarized optical microscopy	562:589	polarized optical microscopy (POM)	562:595	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	5	10	theme	experimental	927:938	arg1	evidence					940:947	this experimental evidence	922:947	this experimental evidence	922:947	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	3	11	theme	films	553:557	arg1	morphology					531:540	the morphology	527:540	the morphology of CNC/PEG films	527:557	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	12	theme	morphology	531:540	arg1	study					518:522	The detailed study	505:522	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis	505:614	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	2	13	theme	properties	457:466	arg1	mapping					429:435	the spatial mapping	417:435	the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation	417:502	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	2	14	theme	films	479:483	arg1	properties					457:466	local mechanical properties	440:466	local mechanical properties of CNC/PEG films	440:483	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	4	15	theme	nonsheared	762:771	arg1	films					773:777	nonsheared films	762:777	nonsheared films	762:777	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	16	theme	/polyethylene	183:195	arg1	glycol					197:202	cellulose nanocrystal (CNC)/polyethylene glycol	156:202	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	16	theme	/polyethylene	183:195	arg1	PEG					205:207	PEG	205:207	PEG	205:207	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	2	17	theme	mechanical	446:455	arg1	properties					457:466	local mechanical properties	440:466	local mechanical properties of CNC/PEG films	440:483	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	5	18	theme	anisotropic	1081:1091	arg1	domains					1093:1099	the anisotropic domains	1077:1099	the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1077:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	3	19	theme	optical	572:578	arg1	POM					592:594	POM	592:594	POM	592:594	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	19	theme	optical	572:578	arg1	microscopy					580:589	polarized optical microscopy	562:589	polarized optical microscopy (POM)	562:595	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	1	20	theme	glycol	197:202	arg1	films					220:224	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	2	21	theme	local	440:444	arg1	properties					457:466	local mechanical properties	440:466	local mechanical properties of CNC/PEG films	440:483	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	5	22	theme	particles	1157:1165	arg1	structure					1140:1148	the shear-induced assembled structure	1112:1148	the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1112:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	5	23	theme	shear-induced	1116:1128	arg1	structure					1140:1148	the shear-induced assembled structure	1112:1148	the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1112:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	1	24	theme	shear	109:113	arg1	flow					115:118	shear flow	109:118	shear flow	109:118	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	25	theme	various	289:295	arg1	ratios					305:310	various CNC/PEG ratios	289:310	various CNC/PEG ratios	289:310	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	4	26	theme	reduced	799:805	arg1	Er					824:825	Er	824:825	Er	824:825	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	26	theme	reduced	799:805	arg1	modulus					815:821	the improved reduced Young's modulus	786:821	the improved reduced Young's modulus (Er)	786:826	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	27	theme	flow	115:118	arg1	distribution					234:245	the distribution	230:245	the distribution of anisotropic phases	230:267	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	27	theme	flow	115:118	arg1	influence					96:104	The influence	92:104	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	92:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	2	28	theme	spatial	421:427	arg1	mapping					429:435	the spatial mapping	417:435	the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation	417:502	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	4	29	theme	data	721:724	arg1	comparison					703:712	A comparison	701:712	A comparison of the data obtained for shear-dried films with nonsheared films	701:777	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	30	theme	CNC/PEG	297:303	arg1	ratios					305:310	various CNC/PEG ratios	289:310	various CNC/PEG ratios	289:310	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	4	31	theme	separation	876:885	arg1	H					842:842	H	842:842	H	842:842	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	31	theme	separation	876:885	arg1	Er					824:825	Er	824:825	Er	824:825	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	31	theme	separation	876:885	arg1	hardness					832:839	hardness	832:839	hardness (H)	832:843	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	31	theme	separation	876:885	arg1	modulus					815:821	the improved reduced Young's modulus	786:821	the improved reduced Young's modulus (Er)	786:826	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	31	theme	separation	876:885	arg1	suppression					850:860	suppression	850:860	suppression of microphase separation	850:885	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	2	32	theme	mixed	349:353	arg1	suspensions					355:365	CNC/PEG mixed suspensions	341:365	CNC/PEG mixed suspensions	341:365	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	0	33	theme	Nanocrystals/Polyethylene	42:66	arg1	Films					85:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	4	34	theme	shear-dried	894:904	arg1	films					906:910	the shear-dried films	890:910	the shear-dried films	890:910	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	3	35	theme	mechanical	646:655	arg1	properties					657:666	the mechanical properties	642:666	the mechanical properties	642:666	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	1	36	theme	composite	210:218	arg1	films					220:224	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	2	37	theme	CNC/PEG	471:477	arg1	films					479:483	CNC/PEG films	471:483	CNC/PEG films	471:483	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	5	38	theme	assembled	1130:1138	arg1	structure					1140:1148	the shear-induced assembled structure	1112:1148	the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1112:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	0	39	theme	Cellulose	32:40	arg1	Films					85:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	4	40	theme	Young	807:811	arg1	Er					824:825	Er	824:825	Er	824:825	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	40	theme	Young	807:811	arg1	modulus					815:821	the improved reduced Young's modulus	786:821	the improved reduced Young's modulus (Er)	786:826	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	41	theme	films	220:224	arg1	properties					142:151	the nanomechanical properties	123:151	the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	123:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	0	42	theme	Composite	75:83	arg1	Films					85:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	3	43	theme	detailed	509:516	arg1	study					518:522	The detailed study	505:522	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis	505:614	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	1	44	from	distribution	234:245	arg1	properties					142:151	the nanomechanical properties	123:151	the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	123:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	2	45	theme	CNC/PEG	341:347	arg1	suspensions					355:365	CNC/PEG mixed suspensions	341:365	CNC/PEG mixed suspensions	341:365	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	0	46	theme	Glycol	68:73	arg1	Films					85:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Cellulose Nanocrystals/Polyethylene Glycol Composite Films	32:89	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	5	47	theme	domains	1093:1099	arg1	generation					1063:1072	the generation	1059:1072	the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1059:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	5	48	theme	microstructural	989:1003	arg1	transition					1005:1014	the microstructural transition	985:1014	the microstructural transition	985:1014	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	1	49	theme	nanomechanical	127:140	arg1	properties					142:151	the nanomechanical properties	123:151	the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	123:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	5	50	theme	CNC	1153:1155	arg1	particles					1157:1165	CNC particles	1153:1165	CNC particles coexisting with the elongated PEG microphases	1153:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	4	51	theme	microphase	865:874	arg1	separation					876:885	microphase separation	865:885	microphase separation	865:885	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	52	theme	shear-dried	739:749	arg1	films					751:755	shear-dried films	739:755	shear-dried films	739:755	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	2	53	dep	traced	385:390	arg1	followed					405:412	followed	405:412	followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation	405:502	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	5	54	theme	elongated	1187:1195	arg1	microphases					1201:1211	the elongated PEG microphases	1183:1211	the elongated PEG microphases	1183:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	2	55	theme	drying	323:328	arg1	process					330:336	the drying process	319:336	the drying process of CNC/PEG mixed suspensions	319:365	Here, the drying process of CNC/PEG mixed suspensions is systematically traced by rheology, followed by the spatial mapping of local mechanical properties of CNC/PEG films by nanoindentation.					
35344341	5	56	theme	shear-drying	1027:1038	arg1	process					1040:1046	the shear-drying process	1023:1046	the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases	1023:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
35344341	3	57	theme	image	601:605	arg1	analysis					607:614	image analysis	601:614	image analysis	601:614	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	1	58	theme	cellulose	156:164	arg1	glycol					197:202	cellulose nanocrystal (CNC)/polyethylene glycol	156:202	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	58	theme	cellulose	156:164	arg1	PEG					205:207	PEG	205:207	PEG	205:207	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	0	59	theme	Films	85:89	arg1	Nanomechanics					15:27	Nanomechanics	15:27	Nanomechanics	15:27	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	0	59	theme	Films	85:89	arg1	Anisotropy					0:9	Anisotropy	0:9	Anisotropy	0:9	Anisotropy and Nanomechanics of Cellulose Nanocrystals/Polyethylene Glycol Composite Films.					
35344341	3	60	theme	flow	695:698	arg1	properties					657:666	the mechanical properties	642:666	the mechanical properties	642:666	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	3	60	theme	flow	695:698	arg1	influence					676:684	the influence	672:684	the influence of shear flow	672:698	The detailed study of the morphology of CNC/PEG films by polarized optical microscopy (POM) and image analysis revealed the link between the mechanical properties and the influence of shear flow.					
35344341	4	61	theme	improved	790:797	arg1	Er					824:825	Er	824:825	Er	824:825	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	4	61	theme	improved	790:797	arg1	modulus					815:821	the improved reduced Young's modulus	786:821	the improved reduced Young's modulus (Er)	786:826	A comparison of the data obtained for shear-dried films with nonsheared films showed the improved reduced Young's modulus (Er) and hardness (H), and suppression of microphase separation in the shear-dried films.					
35344341	1	62	theme	nanocrystal	166:176	arg1	glycol					197:202	cellulose nanocrystal (CNC)/polyethylene glycol	156:202	cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films	156:224	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	1	62	theme	nanocrystal	166:176	arg1	PEG					205:207	PEG	205:207	PEG	205:207	The influence of shear flow on the nanomechanical properties of cellulose nanocrystal (CNC)/polyethylene glycol (PEG) composite films and the distribution of anisotropic phases are investigated at various CNC/PEG ratios.					
35344341	5	63	theme	PEG	1197:1199	arg1	microphases					1201:1211	the elongated PEG microphases	1183:1211	the elongated PEG microphases	1183:1211	Based on this experimental evidence, a mechanism is proposed to explain the microstructural transition during the shear-drying process leading to the generation of the anisotropic domains containing the shear-induced assembled structure of CNC particles coexisting with the elongated PEG microphases.					
36088002	6	0	theme	fuchsin	970:976	arg1	processes					951:959	the degradation processes	935:959	the degradation processes of basic fuchsin, methylene blue and sulfadiazine	935:1009	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	3	1	theme	photocatalytic	538:551	arg1	activity					553:560	relatively good visible light photocatalytic activity	508:560	relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics	508:609	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	6	2	theme	basic	964:968	arg1	fuchsin					970:976	basic fuchsin	964:976	basic fuchsin	964:976	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	1	3	theme	composite	175:183	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	2	4	theme	composite	356:364	arg1	membrane					366:373	the prepared composite membrane	343:373	the prepared composite membrane	343:373	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	5	theme	X-ray	320:324	arg1	diffraction					326:336	single-crystal X-ray diffraction	305:336	single-crystal X-ray diffraction	305:336	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	6	6	theme	first-order	1039:1049	arg1	kinetics					1060:1067	first-order reaction kinetics	1039:1067	first-order reaction kinetics	1039:1067	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	2	7	theme	single-crystal	305:318	arg1	diffraction					326:336	single-crystal X-ray diffraction	305:336	single-crystal X-ray diffraction	305:336	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	8	theme	prepared	347:354	arg1	membrane					366:373	the prepared composite membrane	343:373	the prepared composite membrane	343:373	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	4	9	theme	blue	745:748	arg1	methylene					735:743	methylene blue	735:748	methylene blue	735:748	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
36088002	3	10	theme	visible	524:530	arg1	light					532:536	relatively good visible light	508:536	relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics	508:609	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	7	11	theme	photo-Fenton	1159:1170	arg1	reaction					1172:1179	the photo-Fenton reaction	1155:1179	the photo-Fenton reaction	1155:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	1	12	theme	membrane	185:192	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	7	13	from	membrane	1143:1150	arg1	reaction					1172:1179	the photo-Fenton reaction	1155:1179	the photo-Fenton reaction	1155:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	3	14	dep	concentrations	634:647	arg1	the					614:616	the	614:616	the	614:616	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	3	14	dep	concentrations	634:647	arg1	presence					618:625	presence	618:625	presence	618:625	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	3	15	theme	organic	569:575	arg1	dyes					577:580	organic dyes	569:580	organic dyes	569:580	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	6	16	theme	degradation	939:949	arg1	processes					951:959	the degradation processes	935:959	the degradation processes of basic fuchsin, methylene blue and sulfadiazine	935:1009	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	4	17	theme	fuchsin	726:732	arg1	efficiencies					704:715	the degradation efficiencies	688:715	the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine	688:765	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
36088002	5	18	theme	good	849:852	arg1	activity					869:876	good photocatalytic activity	849:876	good photocatalytic activity	849:876	The composite membrane maintained good photocatalytic activity after four catalytic cycles.					
36088002	1	19	theme	novel	107:111	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	4	20	theme	basic	720:724	arg1	fuchsin					726:732	basic fuchsin	720:732	basic fuchsin	720:732	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
36088002	0	21	theme	acetate	30:36	arg1	membrane					48:55	cellulose acetate composite membrane	20:55	cellulose acetate composite membrane	20:55	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	5	22	theme	catalytic	889:897	arg1	cycles					899:904	four catalytic cycles	884:904	four catalytic cycles	884:904	The composite membrane maintained good photocatalytic activity after four catalytic cycles.					
36088002	7	23	theme	composite	1133:1141	arg1	membrane					1143:1150	the Fe-complex/CA composite membrane	1115:1150	the Fe-complex/CA composite membrane in the photo-Fenton reaction	1115:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	1	24	theme	Fe-complex	113:122	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	2	25	theme	diffuse	427:433	arg1	SEM					396:398	SEM	396:398	SEM	396:398	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	25	theme	diffuse	427:433	arg1	spectroscopy					447:458	FTIR and UV-Vis diffuse reflectance spectroscopy	411:458	spectroscopy	447:458	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	0	26	theme	cellulose	20:28	arg1	membrane					48:55	cellulose acetate composite membrane	20:55	cellulose acetate composite membrane	20:55	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	7	27	theme	membrane	1143:1150	arg1	mechanism					1102:1110	the photocatalytic mechanism	1083:1110	the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction	1083:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	1	28	theme	loaded	124:129	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	2	29	theme	UV-Vis	420:425	arg1	SEM					396:398	SEM	396:398	SEM	396:398	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	29	theme	UV-Vis	420:425	arg1	spectroscopy					447:458	FTIR and UV-Vis diffuse reflectance spectroscopy	411:458	spectroscopy	447:458	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	3	30	theme	light	532:536	arg1	activity					553:560	relatively good visible light photocatalytic activity	508:560	relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics	508:609	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	4	31	theme	degradation	692:702	arg1	efficiencies					704:715	the degradation efficiencies	688:715	the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine	688:765	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
36088002	3	32	theme	Fe-complex/CA	465:477	arg1	membrane					489:496	The Fe-complex/CA composite membrane	461:496	The Fe-complex/CA composite membrane	461:496	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	0	33	theme	composite	38:46	arg1	membrane					48:55	cellulose acetate composite membrane	20:55	cellulose acetate composite membrane	20:55	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	6	34	theme	sulfadiazine	998:1009	arg1	processes					951:959	the degradation processes	935:959	the degradation processes of basic fuchsin, methylene blue and sulfadiazine	935:1009	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	6	35	theme	reaction	1051:1058	arg1	kinetics					1060:1067	first-order reaction kinetics	1039:1067	first-order reaction kinetics	1039:1067	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	6	36	theme	Kinetic	907:913	arg1	studies					915:921	Kinetic studies	907:921	Kinetic studies	907:921	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	3	37	theme	H2O2	652:655	arg1	concentrations					634:647	low concentrations	630:647	low concentrations of H2O2	630:655	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	2	38	theme	FTIR	411:414	arg1	SEM					396:398	SEM	396:398	SEM	396:398	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	38	theme	FTIR	411:414	arg1	spectroscopy					447:458	FTIR and UV-Vis diffuse reflectance spectroscopy	411:458	spectroscopy	447:458	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	0	39	theme	excellent	62:70	arg1	activity					95:102	excellent photo-Fenton catalytic activity	62:102	excellent photo-Fenton catalytic activity	62:102	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	3	40	theme	low	630:632	arg1	concentrations					634:647	low concentrations	630:647	low concentrations of H2O2	630:655	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	1	41	theme	visible-light	131:143	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	7	42	theme	Fe-complex/CA	1119:1131	arg1	membrane					1143:1150	the Fe-complex/CA composite membrane	1115:1150	the Fe-complex/CA composite membrane in the photo-Fenton reaction	1115:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	6	43	theme	blue	989:992	arg1	methylene					979:987	methylene blue	979:992	methylene blue	979:992	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	5	44	theme	photocatalytic	854:867	arg1	activity					869:876	good photocatalytic activity	849:876	good photocatalytic activity	849:876	The composite membrane maintained good photocatalytic activity after four catalytic cycles.					
36088002	1	45	theme	active	145:150	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	6	46	theme	methylene	979:987	arg1	processes					951:959	the degradation processes	935:959	the degradation processes of basic fuchsin, methylene blue and sulfadiazine	935:1009	Kinetic studies showed that the degradation processes of basic fuchsin, methylene blue and sulfadiazine were all in accordance with first-order reaction kinetics.					
36088002	5	47	theme	composite	819:827	arg1	membrane					829:836	The composite membrane	815:836	The composite membrane	815:836	The composite membrane maintained good photocatalytic activity after four catalytic cycles.					
36088002	1	48	theme	cellulose	152:160	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	1	49	theme	tape	235:238	arg1	method					248:253	the tape casting method	231:253	the tape casting method	231:253	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	7	50	theme	photocatalytic	1087:1100	arg1	mechanism					1102:1110	the photocatalytic mechanism	1083:1110	the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction	1083:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	3	51	theme	sulfadiazine	586:597	arg1	antibiotics					599:609	sulfadiazine antibiotics	586:609	sulfadiazine antibiotics	586:609	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	7	52	from	reaction	1172:1179	arg1	mechanism					1102:1110	the photocatalytic mechanism	1083:1110	the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction	1083:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	1	53	theme	acetate	162:168	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	1	54	theme	casting	240:246	arg1	method					248:253	the tape casting method	231:253	the tape casting method	231:253	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	0	55	theme	catalytic	85:93	arg1	activity					95:102	excellent photo-Fenton catalytic activity	62:102	excellent photo-Fenton catalytic activity	62:102	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	3	56	theme	composite	479:487	arg1	membrane					489:496	The Fe-complex/CA composite membrane	461:496	The Fe-complex/CA composite membrane	461:496	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	4	57	theme	methylene	735:743	arg1	efficiencies					704:715	the degradation efficiencies	688:715	the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine	688:765	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
36088002	3	58	theme	good	519:522	arg1	light					532:536	relatively good visible light	508:536	relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics	508:609	The Fe-complex/CA composite membrane exhibited relatively good visible light photocatalytic activity toward organic dyes and sulfadiazine antibiotics in the presence of low concentrations of H2O2.					
36088002	7	59	from	mechanism	1102:1110	arg1	reaction					1172:1179	the photo-Fenton reaction	1155:1179	the photo-Fenton reaction	1155:1179	In addition, the photocatalytic mechanism of the Fe-complex/CA composite membrane in the photo-Fenton reaction was also discussed in detail.					
36088002	0	60	theme	photo-Fenton	72:83	arg1	activity					95:102	excellent photo-Fenton catalytic activity	62:102	excellent photo-Fenton catalytic activity	62:102	Fe-complex modified cellulose acetate composite membrane with excellent photo-Fenton catalytic activity.					
36088002	2	61	theme	reflectance	435:445	arg1	SEM					396:398	SEM	396:398	SEM	396:398	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	2	61	theme	reflectance	435:445	arg1	spectroscopy					447:458	FTIR and UV-Vis diffuse reflectance spectroscopy	411:458	spectroscopy	447:458	The Fe-complex was structurally characterized by single-crystal X-ray diffraction, and the prepared composite membrane was characterized by SEM, XPS, XRD, FTIR and UV-Vis diffuse reflectance spectroscopy.					
36088002	1	62	theme	CA	171:172	arg1	Fe-complex/CA					195:207	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA)	105:208	A novel Fe-complex loaded visible-light active cellulose acetate (CA) composite membrane (Fe-complex/CA) was fabricated using the tape casting method.					
36088002	4	63	theme	sulfadiazine	754:765	arg1	efficiencies					704:715	the degradation efficiencies	688:715	the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine	688:765	After irradiation for 60 min, the degradation efficiencies of basic fuchsin, methylene blue and sulfadiazine reached 100 %, 93.4 % and 95.7 %, respectively.					
35169269	11	0	theme	throughput	2764:2773	arg1	methods					2793:2799	future high throughput glycome profiling methods	2752:2799	future high throughput glycome profiling methods	2752:2799	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	5	1	used	utilized	1206:1213	arg2	%					1140:1140	the remaining 15-25%	1121:1140	the remaining 15-25%	1121:1140	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	1	used	utilized	1206:1213	arg2	oligosaccharides					1167:1182	soluble recalcitrant oligosaccharides	1146:1182	soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms	1146:1231	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	6	2	theme	recalcitrant	1297:1308	arg1	oligosaccharides					1310:1325	the soluble recalcitrant oligosaccharides	1285:1325	the soluble recalcitrant oligosaccharides	1285:1325	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	2	3	theme	bio-based	417:425	arg1	technologies					427:438	bio-based technologies	417:438	bio-based technologies	417:438	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	11	4	from	biomarkers	2875:2884	arg1	present					2864:2870	present	2864:2870	present	2864:2870	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	11	5	theme	future	2752:2757	arg1	methods					2793:2799	future high throughput glycome profiling methods	2752:2799	future high throughput glycome profiling methods	2752:2799	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	8	6	theme	laser	1963:1967	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	6	theme	laser	1963:1967	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	6	theme	laser	1963:1967	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	3	7	theme	present	605:611	arg1	carbohydrates					591:603	complex carbohydrates	583:603	complex carbohydrates present in plant cell wall	583:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	8	theme	glycome	1786:1792	arg1	profiling					1794:1802	glycome profiling	1786:1802	glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1786:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	7	9	theme	higher	1526:1531	arg1	degree					1533:1538	higher degree	1526:1538	higher degree of polymerization (DP) containing methylated uronic acid substitutions	1526:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	11	10	used	used	2813:2816	arg2	versions					2740:2747	more advanced versions	2726:2747	more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications	2726:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	4	11	theme	lignocellulosic	695:709	arg1	biomass					711:717	lignocellulosic biomass	695:717	lignocellulosic biomass	695:717	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	8	12	theme	ionization	1980:1989	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	12	theme	ionization	1980:1989	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	12	theme	ionization	1980:1989	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	3	13	theme	complex	583:589	arg1	carbohydrates					591:603	complex carbohydrates	583:603	complex carbohydrates present in plant cell wall	583:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	14	theme	structurally-informative	2045:2068	arg1	chromatography					2145:2158	gas chromatography	2141:2158	gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	2141:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	14	theme	structurally-informative	2045:2068	arg1	peaks					2081:2085	structurally-informative diagnostic peaks	2045:2085	structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra	2045:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	10	15	theme	linkage	2633:2639	arg1	analysis					2641:2648	specific linkage analysis	2624:2648	specific linkage analysis using mAbs in a high-throughput system	2624:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	8	16	theme	mass	2006:2009	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	16	theme	mass	2006:2009	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	16	theme	mass	2006:2009	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	17	theme	biomass	1816:1822	arg1	mAbs					1863:1866	mAbs	1863:1866	mAbs	1863:1866	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	17	theme	biomass	1816:1822	arg1	antibodies					1851:1860	plant biomass glycan specific monoclonal antibodies	1810:1860	plant biomass glycan specific monoclonal antibodies (mAbs)	1810:1867	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	7	18	contain	containing	1563:1572	arg1	DP					1559:1560	DP	1559:1560	DP	1559:1560	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	7	18	contain	containing	1563:1572	arg2	substitutions					1597:1609	methylated uronic acid substitutions	1574:1609	methylated uronic acid substitutions	1574:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	7	18	contain	containing	1563:1572	arg1	polymerization					1543:1556	polymerization	1543:1556	polymerization (DP) containing methylated uronic acid substitutions	1543:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	10	19	theme	based	2471:2475	arg1	method					2508:2513	a new biotin-coupling based oligosaccharide immobilization method	2449:2513	a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2449:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	11	20	from	present	2864:2870	arg1	biomarkers					2875:2884	biomarkers	2875:2884	biomarkers for diagnostic applications	2875:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	10	21	theme	high-throughput	2666:2680	arg1	system					2682:2687	a high-throughput system	2664:2687	a high-throughput system	2664:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	0	22	theme	mass	149:152	arg1	spectrometry					154:165	mass spectrometry	149:165	mass spectrometry	149:165	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	3	23	theme	plant	616:620	arg1	wall					627:630	plant cell wall	616:630	plant cell wall	616:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	24	theme	specific	1831:1838	arg1	mAbs					1863:1866	mAbs	1863:1866	mAbs	1863:1866	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	24	theme	specific	1831:1838	arg1	antibodies					1851:1860	plant biomass glycan specific monoclonal antibodies	1810:1860	plant biomass glycan specific monoclonal antibodies (mAbs)	1810:1867	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	1	25	theme	Recalcitrant	248:259	arg1	Oligosaccharides					261:276	Recalcitrant Oligosaccharides	248:276	Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover	248:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	4	26	theme	microbial	932:940	arg1	fermentation					942:953	microbial fermentation	932:953	microbial fermentation	932:953	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	11	27	theme	new	2695:2697	arg1	approach					2699:2706	This new approach	2690:2706	This new approach	2690:2706	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	6	28	theme	charcoal	1350:1357	arg1	combination					1335:1345	a combination	1333:1345	a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes	1333:1478	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	5	29	theme	sugars	1076:1081	arg1	%					1059:1059	only 75-85%	1049:1059	only 75-85% of the soluble sugars generated	1049:1091	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	29	theme	sugars	1076:1081	arg1	sugars					1107:1112	monomeric sugars	1097:1112	monomeric sugars	1097:1112	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	29	theme	sugars	1076:1081	arg1	sugars					1076:1081	the soluble sugars	1064:1081	the soluble sugars generated	1064:1091	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	1	30	from	Oligosaccharides	261:276	arg1	Stover					302:307	AFEX Pretreated Corn Stover	281:307	AFEX Pretreated Corn Stover	281:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	1	31	from	Stover	302:307	arg1	Analysis					236:243	Comprehensive Analysis	222:243	Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover	222:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	3	32	theme	simple	635:640	arg1	sugars					642:647	simple sugars	635:647	simple sugars such as glucose, xylose, and arabinose	635:686	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	3	32	theme	simple	635:640	arg1	glucose					657:663	glucose	657:663	glucose	657:663	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	3	32	theme	simple	635:640	arg1	arabinose					678:686	arabinose	678:686	arabinose	678:686	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	3	32	theme	simple	635:640	arg1	xylose					666:671	xylose	666:671	xylose	666:671	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	6	33	theme	soluble	1289:1295	arg1	oligosaccharides					1310:1325	the soluble recalcitrant oligosaccharides	1285:1325	the soluble recalcitrant oligosaccharides	1285:1325	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	10	34	theme	immobilization	2493:2506	arg1	method					2508:2513	a new biotin-coupling based oligosaccharide immobilization method	2449:2513	a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2449:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	1	35	theme	Novel	168:172	arg1	Methods					210:216	Novel Immunological and Mass Spectrometry Methods	168:216	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.	168:308	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	7	36	theme	lower	1674:1678	arg1	DP					1680:1681	lower DP	1674:1681	lower DP	1674:1681	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	3	37	from	wall	627:630	arg1	present					605:611	present	605:611	present	605:611	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	38	theme	sugar	1885:1889	arg1	linkages					1891:1898	sugar linkages	1885:1898	sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1885:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	0	39	from	structure	18:26	arg1	hydrolysate					80:90	hydrolysate	80:90	hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry	80:165	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	8	40	theme	ion	2107:2109	arg1	spectra					2132:2138	negative ion post-secondary decay spectra	2098:2138	negative ion post-secondary decay spectra	2098:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	5	41	theme	remaining	1125:1133	arg1	%					1140:1140	the remaining 15-25%	1121:1140	the remaining 15-25%	1121:1140	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	41	theme	remaining	1125:1133	arg1	oligosaccharides					1167:1182	soluble recalcitrant oligosaccharides	1146:1182	soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms	1146:1231	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	1	42	theme	Spectrometry	197:208	arg1	Methods					210:216	Novel Immunological and Mass Spectrometry Methods	168:216	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.	168:308	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	7	43	theme	commercial	1642:1651	arg1	mixtures					1660:1667	commercial enzyme mixtures	1642:1667	commercial enzyme mixtures	1642:1667	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	10	44	theme	soluble	2559:2565	arg1	oligosaccharides					2567:2582	the low DP soluble oligosaccharides	2548:2582	the low DP soluble oligosaccharides	2548:2582	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	4	45	theme	Ammonia	809:815	arg1	AFEX					834:837	AFEX	834:837	AFEX	834:837	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	45	theme	Ammonia	809:815	arg1	Expansion					823:831	Ammonia Fiber Expansion	809:831	Ammonia Fiber Expansion (AFEX)	809:838	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	3	46	from	present	605:611	arg1	wall					627:630	plant cell wall	616:630	plant cell wall	616:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	0	47	theme	biotin-based	114:125	arg1	profiling					135:143	high-throughput biotin-based glycome profiling	98:143	high-throughput biotin-based glycome profiling	98:143	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	8	48	theme	cell	1909:1912	arg1	walls					1914:1918	plant cell walls	1903:1918	plant cell walls	1903:1918	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	4	49	theme	desired	966:972	arg1	products					974:981	desired products	966:981	desired products	966:981	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	11	50	attach	present	2864:2870	arg1	biomarkers					2875:2884	biomarkers	2875:2884	biomarkers for diagnostic applications	2875:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	11	50	attach	present	2864:2870	arg2	oligosaccharides					2847:2862	oligosaccharides	2847:2862	oligosaccharides present in biomarkers for diagnostic applications	2847:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	6	51	dep	chromatography	1414:1427	arg1	properties					1458:1467	their inhibitory properties	1441:1467	their inhibitory properties	1441:1467	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	0	52	from	composition	32:42	arg1	hydrolysate					80:90	hydrolysate	80:90	hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry	80:165	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	2	53	used	used	397:400	arg2	biomass					326:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	2	53	used	used	397:400	arg2	alternative					351:361	a sustainable alternative	337:361	a sustainable alternative to fossil fuel	337:376	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	4	54	theme	thermochemical	776:789	arg1	treatment					791:799	thermochemical treatment	776:799	thermochemical treatment such as Ammonia Fiber Expansion (AFEX)	776:838	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	3	55	attach	present	605:611	arg1	wall					627:630	plant cell wall	616:630	plant cell wall	616:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	3	55	attach	present	605:611	arg2	carbohydrates					591:603	complex carbohydrates	583:603	complex carbohydrates present in plant cell wall	583:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	56	theme	oligosaccharide	2214:2228	arg1	linkages					2236:2243	oligosaccharide sugar linkages	2214:2243	oligosaccharide sugar linkages with and without derivatization	2214:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	11	57	theme	methods	2793:2799	arg1	versions					2740:2747	more advanced versions	2726:2747	more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications	2726:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	7	58	theme	uronic	1585:1590	arg1	substitutions					1597:1609	methylated uronic acid substitutions	1574:1609	methylated uronic acid substitutions	1574:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	6	59	theme	inhibitory	1447:1456	arg1	properties					1458:1467	their inhibitory properties	1441:1467	their inhibitory properties	1441:1467	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	5	60	theme	soluble	1146:1152	arg1	%					1140:1140	the remaining 15-25%	1121:1140	the remaining 15-25%	1121:1140	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	60	theme	soluble	1146:1152	arg1	oligosaccharides					1167:1182	soluble recalcitrant oligosaccharides	1146:1182	soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms	1146:1231	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	7	61	with	oligosaccharides	1504:1519	arg1	degree					1533:1538	higher degree	1526:1538	higher degree of polymerization (DP) containing methylated uronic acid substitutions	1526:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	1	62	theme	AFEX	281:284	arg1	Stover					302:307	AFEX Pretreated Corn Stover	281:307	AFEX Pretreated Corn Stover	281:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	0	63	dep	structure	18:26	arg1	the					14:16	the	14:16	the	14:16	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	1	64	theme	Corn	297:300	arg1	Stover					302:307	AFEX Pretreated Corn Stover	281:307	AFEX Pretreated Corn Stover	281:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	7	65	theme	polymerization	1543:1556	arg1	degree					1533:1538	higher degree	1526:1538	higher degree of polymerization (DP) containing methylated uronic acid substitutions	1526:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	5	66	theme	fungal	1015:1020	arg1	enzymes					1022:1028	commercial fungal enzymes	1004:1028	commercial fungal enzymes	1004:1028	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	11	67	theme	advanced	2731:2738	arg1	versions					2740:2747	more advanced versions	2726:2747	more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications	2726:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	8	68	theme	post-secondary	2111:2124	arg1	spectra					2132:2138	negative ion post-secondary decay spectra	2098:2138	negative ion post-secondary decay spectra	2098:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	69	theme	matrix-assisted	1947:1961	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	69	theme	matrix-assisted	1947:1961	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	69	theme	matrix-assisted	1947:1961	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	3	70	theme	cost	545:548	arg1	processes					562:570	cost competitive processes	545:570	cost competitive processes	545:570	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	8	71	theme	several	1740:1746	arg1	techniques					1762:1771	several complementary techniques	1740:1771	several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1740:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	11	72	theme	glycome	2775:2781	arg1	methods					2793:2799	future high throughput glycome profiling methods	2752:2799	future high throughput glycome profiling methods	2752:2799	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	8	73	theme	desorption	1969:1978	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	73	theme	desorption	1969:1978	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	73	theme	desorption	1969:1978	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	74	theme	techniques	1762:1771	arg1	use					1733:1735	the use	1729:1735	the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1729:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	11	75	theme	high	2759:2762	arg1	methods					2793:2799	future high throughput glycome profiling methods	2752:2799	future high throughput glycome profiling methods	2752:2799	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	8	76	theme	time-of-flight	1991:2004	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	76	theme	time-of-flight	1991:2004	arg1	MALDI-TOF-MS					2025:2036	MALDI-TOF-MS	2025:2036	MALDI-TOF-MS	2025:2036	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	76	theme	time-of-flight	1991:2004	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	2	77	theme	sustainable	339:349	arg1	alternative					351:361	a sustainable alternative	337:361	a sustainable alternative to fossil fuel	337:376	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	2	77	theme	sustainable	339:349	arg1	biomass					326:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	0	78	theme	recalcitrant	47:58	arg1	oligosaccharides					60:75	recalcitrant oligosaccharides	47:75	recalcitrant oligosaccharides	47:75	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	3	79	theme	cell	622:625	arg1	wall					627:630	plant cell wall	616:630	plant cell wall	616:630	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	1	80	theme	Comprehensive	222:234	arg1	Analysis					236:243	Comprehensive Analysis	222:243	Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover	222:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	10	81	theme	specific	2624:2631	arg1	analysis					2641:2648	specific linkage analysis	2624:2648	specific linkage analysis using mAbs in a high-throughput system	2624:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	6	82	theme	separation	1376:1385	arg1	combination					1335:1345	a combination	1333:1345	a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes	1333:1478	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	8	83	theme	plant	1810:1814	arg1	mAbs					1863:1866	mAbs	1863:1866	mAbs	1863:1866	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	83	theme	plant	1810:1814	arg1	antibodies					1851:1860	plant biomass glycan specific monoclonal antibodies	1810:1860	plant biomass glycan specific monoclonal antibodies (mAbs)	1810:1867	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	4	84	theme	enzyme	910:915	arg1	hydrolysis					917:926	enzyme hydrolysis	910:926	enzyme hydrolysis	910:926	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	5	85	theme	soluble	1068:1074	arg1	sugars					1076:1081	the soluble sugars	1064:1081	the soluble sugars generated	1064:1091	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	8	86	theme	glycan	1824:1829	arg1	mAbs					1863:1866	mAbs	1863:1866	mAbs	1863:1866	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	86	theme	glycan	1824:1829	arg1	antibodies					1851:1860	plant biomass glycan specific monoclonal antibodies	1810:1860	plant biomass glycan specific monoclonal antibodies (mAbs)	1810:1867	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	1	87	theme	Oligosaccharides	261:276	arg1	Analysis					236:243	Comprehensive Analysis	222:243	Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover	222:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	7	88	theme	neutral	1687:1693	arg1	oligosaccharides					1695:1710	neutral oligosaccharides	1687:1710	neutral oligosaccharides	1687:1710	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	6	89	theme	exclusion	1404:1412	arg1	chromatography					1414:1427	size exclusion chromatography	1399:1427	size exclusion chromatography	1399:1427	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	8	90	theme	diagnostic	2070:2079	arg1	chromatography					2145:2158	gas chromatography	2141:2158	gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	2141:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	90	theme	diagnostic	2070:2079	arg1	peaks					2081:2085	structurally-informative diagnostic peaks	2045:2085	structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra	2045:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	91	theme	monoclonal	1840:1849	arg1	mAbs					1863:1866	mAbs	1863:1866	mAbs	1863:1866	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	91	theme	monoclonal	1840:1849	arg1	antibodies					1851:1860	plant biomass glycan specific monoclonal antibodies	1810:1860	plant biomass glycan specific monoclonal antibodies (mAbs)	1810:1867	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	4	92	theme	biological	881:890	arg1	treatment					892:900	biological treatment	881:900	biological treatment	881:900	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	11	93	theme	present	2864:2870	arg1	oligosaccharides					2847:2862	oligosaccharides	2847:2862	oligosaccharides present in biomarkers for diagnostic applications	2847:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	10	94	theme	oligosaccharide	2477:2491	arg1	method					2508:2513	a new biotin-coupling based oligosaccharide immobilization method	2449:2513	a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2449:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	8	95	from	linkages	1891:1898	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	95	from	linkages	1891:1898	arg1	walls					1914:1918	plant cell walls	1903:1918	plant cell walls	1903:1918	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	95	from	linkages	1891:1898	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	96	theme	negative	2098:2105	arg1	spectra					2132:2138	negative ion post-secondary decay spectra	2098:2138	negative ion post-secondary decay spectra	2098:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	2	97	theme	Lignocellulosic	310:324	arg1	alternative					351:361	a sustainable alternative	337:361	a sustainable alternative to fossil fuel	337:376	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	2	97	theme	Lignocellulosic	310:324	arg1	biomass					326:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass	310:332	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	1	98	from	Analysis	236:243	arg1	Stover					302:307	AFEX Pretreated Corn Stover	281:307	AFEX Pretreated Corn Stover	281:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	1	99	theme	Immunological	174:186	arg1	Methods					210:216	Novel Immunological and Mass Spectrometry Methods	168:216	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.	168:308	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	7	100	theme	enzyme	1653:1658	arg1	mixtures					1660:1667	commercial enzyme mixtures	1642:1667	commercial enzyme mixtures	1642:1667	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	11	101	theme	diagnostic	2890:2899	arg1	applications					2901:2912	diagnostic applications	2890:2912	diagnostic applications	2890:2912	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	6	102	theme	size	1399:1402	arg1	chromatography					1414:1427	size exclusion chromatography	1399:1427	size exclusion chromatography	1399:1427	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	0	103	theme	high-throughput	98:112	arg1	profiling					135:143	high-throughput biotin-based glycome profiling	98:143	high-throughput biotin-based glycome profiling	98:143	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	6	104	from	chromatography	1414:1427	arg1	enzymes					1472:1478	enzymes	1472:1478	enzymes	1472:1478	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	1	105	theme	Mass	192:195	arg1	Methods					210:216	Novel Immunological and Mass Spectrometry Methods	168:216	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.	168:308	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	6	106	theme	celite-based	1363:1374	arg1	separation					1376:1385	celite-based separation	1363:1385	celite-based separation	1363:1385	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	0	107	theme	glycome	127:133	arg1	profiling					135:143	high-throughput biotin-based glycome profiling	98:143	high-throughput biotin-based glycome profiling	98:143	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	6	108	from	studies	1433:1439	arg1	enzymes					1472:1478	enzymes	1472:1478	enzymes	1472:1478	Previously, we successfully separated and purified the soluble recalcitrant oligosaccharides using a combination of charcoal and celite-based separation followed by size exclusion chromatography and studies their inhibitory properties on enzymes.					
35169269	10	109	theme	biotin-coupling	2455:2469	arg1	method					2508:2513	a new biotin-coupling based oligosaccharide immobilization method	2449:2513	a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2449:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	2	110	theme	fossil	366:371	arg1	fuel					373:376	fossil fuel	366:376	fossil fuel	366:376	Lignocellulosic biomass is a sustainable alternative to fossil fuel and is extensively used for developing bio-based technologies to produce products such as food, feed, fuel, and chemicals.					
35169269	10	111	theme	DP	2556:2557	arg1	oligosaccharides					2567:2582	the low DP soluble oligosaccharides	2548:2582	the low DP soluble oligosaccharides	2548:2582	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	8	112	theme	gas	2141:2143	arg1	chromatography					2145:2158	gas chromatography	2141:2158	gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	2141:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	112	theme	gas	2141:2143	arg1	peaks					2081:2085	structurally-informative diagnostic peaks	2045:2085	structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra	2045:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	5	113	theme	monomeric	1097:1105	arg1	sugars					1107:1112	monomeric sugars	1097:1112	monomeric sugars	1097:1112	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	113	theme	monomeric	1097:1105	arg1	%					1059:1059	only 75-85%	1049:1059	only 75-85% of the soluble sugars generated	1049:1091	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	113	theme	monomeric	1097:1105	arg1	sugars					1076:1081	the soluble sugars	1064:1081	the soluble sugars generated	1064:1091	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	8	114	theme	plant	1903:1907	arg1	walls					1914:1918	plant cell walls	1903:1918	plant cell walls	1903:1918	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	115	theme	decay	2126:2130	arg1	spectra					2132:2138	negative ion post-secondary decay spectra	2098:2138	negative ion post-secondary decay spectra	2098:2138	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	4	116	theme	Fiber	817:821	arg1	AFEX					834:837	AFEX	834:837	AFEX	834:837	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	116	theme	Fiber	817:821	arg1	Expansion					823:831	Ammonia Fiber Expansion	809:831	Ammonia Fiber Expansion (AFEX)	809:838	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	10	117	theme	low	2552:2554	arg1	oligosaccharides					2567:2582	the low DP soluble oligosaccharides	2548:2582	the low DP soluble oligosaccharides	2548:2582	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	8	118	theme	sugar	2230:2234	arg1	linkages					2236:2243	oligosaccharide sugar linkages	2214:2243	oligosaccharide sugar linkages with and without derivatization	2214:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	10	119	theme	new	2451:2453	arg1	method					2508:2513	a new biotin-coupling based oligosaccharide immobilization method	2449:2513	a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2449:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	8	120	theme	mass	2172:2175	arg1	GC-MS					2191:2195	GC-MS	2191:2195	GC-MS	2191:2195	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	120	theme	mass	2172:2175	arg1	spectrometry					2177:2188	mass spectrometry	2172:2188	mass spectrometry (GC-MS)	2172:2196	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	121	theme	enzymatic	1924:1932	arg1	spectrometry					2011:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry	1947:2022	matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1947:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	8	121	theme	enzymatic	1924:1932	arg1	hydrolysate					1934:1944	enzymatic hydrolysate	1924:1944	enzymatic hydrolysate	1924:1944	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35169269	11	122	theme	profiling	2783:2791	arg1	methods					2793:2799	future high throughput glycome profiling methods	2752:2799	future high throughput glycome profiling methods	2752:2799	This new approach will help develop more advanced versions of future high throughput glycome profiling methods that can be used to separate and characterize oligosaccharides present in biomarkers for diagnostic applications.					
35169269	4	123	theme	treatment	791:799	arg1	acid					848:851	dilute acid	841:851	dilute acid (DA)	841:856	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	123	theme	treatment	791:799	arg1	DA					854:855	DA	854:855	DA	854:855	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	123	theme	treatment	791:799	arg1	treatment					892:900	biological treatment	881:900	biological treatment	881:900	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	123	theme	treatment	791:799	arg1	combination					761:771	a combination	759:771	a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX)	759:838	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	9	124	dep	mAbs	2372:2375	arg1	mAbs					2372:2375	mAbs binding and characterization	2372:2404	mAbs binding and characterization	2372:2404	Since oligosaccharides (DP 4-20) are small, it is challenging to mobilize these molecules for mAbs binding and characterization.					
35169269	9	124	dep	mAbs	2372:2375	arg1	characterization					2389:2404	characterization	2389:2404	characterization	2389:2404	Since oligosaccharides (DP 4-20) are small, it is challenging to mobilize these molecules for mAbs binding and characterization.					
35169269	9	124	dep	mAbs	2372:2375	arg1	binding					2377:2383	binding	2377:2383	binding	2377:2383	Since oligosaccharides (DP 4-20) are small, it is challenging to mobilize these molecules for mAbs binding and characterization.					
35169269	4	125	theme	dilute	841:846	arg1	acid					848:851	dilute acid	841:851	dilute acid (DA)	841:856	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	4	125	theme	dilute	841:846	arg1	DA					854:855	DA	854:855	DA	854:855	Since lignocellulosic biomass is highly recalcitrant, it must undergo a combination of thermochemical treatment such as Ammonia Fiber Expansion (AFEX), dilute acid (DA), Ionic Liquid (IL) and biological treatment such as enzyme hydrolysis and microbial fermentation to produce desired products.					
35169269	0	126	theme	oligosaccharides	60:75	arg1	structure					18:26	structure	18:26	structure	18:26	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	0	126	theme	oligosaccharides	60:75	arg1	composition					32:42	composition	32:42	composition	32:42	Understanding the structure and composition of recalcitrant oligosaccharides in hydrolysate using high-throughput biotin-based glycome profiling and mass spectrometry.					
35169269	7	127	theme	acid	1592:1595	arg1	substitutions					1597:1609	methylated uronic acid substitutions	1574:1609	methylated uronic acid substitutions	1574:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	10	128	theme	micro-plate	2592:2602	arg1	surface					2604:2610	a micro-plate surface	2590:2610	a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system	2590:2687	To overcome this problem, we have applied a new biotin-coupling based oligosaccharide immobilization method that successfully tagged most of the low DP soluble oligosaccharides on to a micro-plate surface followed by specific linkage analysis using mAbs in a high-throughput system.					
35169269	3	129	theme	competitive	550:560	arg1	processes					562:570	cost competitive processes	545:570	cost competitive processes	545:570	The key to these technologies is to develop cost competitive processes to convert complex carbohydrates present in plant cell wall to simple sugars such as glucose, xylose, and arabinose.					
35169269	5	130	theme	recalcitrant	1154:1165	arg1	%					1140:1140	the remaining 15-25%	1121:1140	the remaining 15-25%	1121:1140	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	5	130	theme	recalcitrant	1154:1165	arg1	oligosaccharides					1167:1182	soluble recalcitrant oligosaccharides	1146:1182	soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms	1146:1231	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	7	131	theme	methylated	1574:1583	arg1	substitutions					1597:1609	methylated uronic acid substitutions	1574:1609	methylated uronic acid substitutions	1574:1609	We discovered that the oligosaccharides with higher degree of polymerization (DP) containing methylated uronic acid substitutions were more recalcitrant towards commercial enzyme mixtures than lower DP and neutral oligosaccharides.					
35169269	1	132	theme	Pretreated	286:295	arg1	Stover					302:307	AFEX Pretreated Corn Stover	281:307	AFEX Pretreated Corn Stover	281:307	Novel Immunological and Mass Spectrometry Methods for Comprehensive Analysis of Recalcitrant Oligosaccharides in AFEX Pretreated Corn Stover.					
35169269	5	133	theme	commercial	1004:1013	arg1	enzymes					1022:1028	commercial fungal enzymes	1004:1028	commercial fungal enzymes	1004:1028	However, when using commercial fungal enzymes during hydrolysis, only 75-85% of the soluble sugars generated are monomeric sugars, while the remaining 15-25% are soluble recalcitrant oligosaccharides that cannot be easily utilized by microorganisms.					
35169269	8	134	theme	complementary	1748:1760	arg1	techniques					1762:1771	several complementary techniques	1740:1771	several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization	1740:2275	Here, we report the use of several complementary techniques that include glycome profiling using plant biomass glycan specific monoclonal antibodies (mAbs) to characterize sugar linkages in plant cell walls and enzymatic hydrolysate, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using structurally-informative diagnostic peaks offered by negative ion post-secondary decay spectra, gas chromatography followed by mass spectrometry (GC-MS) to characterize oligosaccharide sugar linkages with and without derivatization.					
35697582	4	0	theme	BPH	869:871	arg1	tissue					890:895	human BPH ex vivo prostate tissue	863:895	human BPH ex vivo prostate tissue	863:895	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	6	1	theme	tissue	1102:1107	arg1	samples					1109:1115	the tissue samples	1098:1115	the tissue samples	1098:1115	Post-treatment, the hybrid gels and the tissue samples exhibited differential reduction in stiffness as measured by SWE.					
35697582	10	2	theme	useful	1899:1904	arg1	alternative					1921:1931	a useful cost-effective alternative	1897:1931	a useful cost-effective alternative for developing and evaluating different treatment protocols	1897:1991	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	2	3	theme	soft	367:370	arg1	tissues					372:378	soft tissues	367:378	soft tissues	367:378	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	4	dep	properties	326:335	arg1	the					313:315	the	313:315	the	313:315	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	9	5	theme	Young	1677:1681	arg1	modulus					1685:1691	comparable or higher Young's modulus	1656:1691	comparable or higher Young's modulus	1656:1691	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	9	6	theme	modulus	1685:1691	arg1	agarose					1645:1651	agarose	1645:1651	agarose of comparable or higher Young's modulus by a factor >10	1645:1707	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	3	7	with	hydrogel	639:646	arg1	toughness					658:666	high toughness	653:666	high toughness	653:666	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	9	8	theme	comparable	1656:1665	arg1	modulus					1685:1691	comparable or higher Young's modulus	1656:1691	comparable or higher Young's modulus	1656:1691	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	10	9	theme	different	1963:1971	arg1	protocols					1983:1991	different treatment protocols	1963:1991	different treatment protocols	1963:1991	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	2	10	theme	acoustic	317:324	arg1	properties					326:335	acoustic properties	317:335	acoustic properties	317:335	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	8	11	theme	tissue	1474:1479	arg1	samples					1481:1487	tissue samples	1474:1487	tissue samples	1474:1487	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	2	12	used	used	263:266	arg2	gels					248:251	Agarose and polyacrylamide gels	221:251	gels	248:251	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	10	13	theme	ex	1811:1812	arg1	tissue					1819:1824	BPH prostate ex vivo tissue	1798:1824	BPH prostate ex vivo tissue	1798:1824	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	4	14	theme	tissue	890:895	arg1	representative					845:858	representative	845:858	representative	845:858	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	4	14	theme	tissue	890:895	arg1	stiffness					735:743	The stiffness	731:743	The stiffness	731:743	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	8	15	theme	Phase	1310:1314	arg1	microscopy					1325:1334	Phase contrast microscopy	1310:1334	Phase contrast microscopy of the gel samples	1310:1353	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	10	16	theme	BPH	1798:1800	arg1	tissue					1819:1824	BPH prostate ex vivo tissue	1798:1824	BPH prostate ex vivo tissue	1798:1824	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	1	17	theme	Tissue-mimicking	97:112	arg1	gels					114:117	Tissue-mimicking gels	97:117	Tissue-mimicking gels	97:117	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	3	18	theme	transparent	627:637	arg1	hydrogel					639:646	an optically transparent hydrogel	614:646	an optically transparent hydrogel with high toughness	614:666	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	19	located	found	503:507	arg1	diseases					556:563	other diseases	550:563	other diseases that are potentially treatable with histotripsy	550:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	19	located	found	503:507	arg1	hyperplasia					528:538	benign prostate hyperplasia	512:538	benign prostate hyperplasia (BPH)	512:544	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	19	located	found	503:507	arg1	BPH					541:543	BPH	541:543	BPH	541:543	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	19	located	found	503:507	arg2	tissue					496:501	pathologic fibrous tissue	477:501	pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy	477:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	5	20	theme	excised	933:939	arg1	samples					960:966	excised ex vivo BPH tissue samples	933:966	excised ex vivo BPH tissue samples	933:966	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	7	21	theme	hyperechoic	1245:1255	arg1	zones					1257:1261	hyperechoic zones	1245:1261	hyperechoic zones	1245:1261	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	9	22	theme	hybrid	1553:1558	arg1	gel					1560:1562	the hybrid gel	1549:1562	the hybrid gel	1549:1562	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	8	23	theme	samples	1347:1353	arg1	microscopy					1325:1334	Phase contrast microscopy	1310:1334	Phase contrast microscopy of the gel samples	1310:1353	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	0	24	theme	Focused	67:73	arg1	Therapies					86:94	Focused Ultrasound Therapies	67:94	Focused Ultrasound Therapies	67:94	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	1	25	theme	treatment	175:183	arg1	parameters					185:194	histotripsy treatment parameters	163:194	histotripsy treatment parameters with immediate feedback	163:218	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	10	26	theme	histotripsy	1857:1867	arg1	treatment					1869:1877	histotripsy treatment	1857:1877	histotripsy treatment	1857:1877	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	9	27	located	observed	1593:1600	arg1	tissue					1613:1618	ex vivo tissue	1605:1618	ex vivo tissue	1605:1618	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	9	27	located	observed	1593:1600	arg2	what					1579:1582	what	1579:1582	what	1579:1582	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	2	28	theme	treatment	280:288	arg1	outcomes					290:297	treatment outcomes	280:297	treatment outcomes	280:297	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	4	29	theme	wave	773:776	arg1	SWE					792:794	shear wave elastography (SWE) and indentometry techniques	767:823	SWE	792:794	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	9	30	theme	ex	1605:1606	arg1	tissue					1613:1618	ex vivo tissue	1605:1618	ex vivo tissue	1605:1618	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	3	31	with	treatable	586:594	arg1	histotripsy					601:611	histotripsy	601:611	histotripsy	601:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	2	32	theme	connective	449:458	arg1	tissue					460:465	fibrous connective tissue	441:465	fibrous connective tissue	441:465	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	8	33	theme	target	1408:1413	arg1	dimensions					1422:1431	the target lesion dimensions	1404:1431	the target lesion dimensions	1404:1431	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	0	34	theme	Tough	15:19	arg1	Phantoms					30:37	Tough Hydrogel Phantoms	15:37	Tough Hydrogel Phantoms	15:37	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	5	35	theme	tissue	953:958	arg1	samples					960:966	excised ex vivo BPH tissue samples	933:966	excised ex vivo BPH tissue samples	933:966	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	0	36	theme	Phantoms	30:37	arg1	Development					0:10	Development	0:10	Development of Tough Hydrogel Phantoms	0:37	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	4	37	dep	ex	873:874	arg1	vivo					876:879	vivo	876:879	vivo	876:879	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	5	38	theme	different	1022:1030	arg1	frequencies					1049:1059	different pulse repetition frequencies	1022:1059	different pulse repetition frequencies	1022:1059	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	10	39	contain	have	1830:1833	arg1	hydrogels					1752:1760	the developed hydrogels	1738:1760	the developed hydrogels	1738:1760	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	10	39	contain	have	1830:1833	arg2	response					1845:1852	a similar response	1835:1852	a similar response to histotripsy treatment	1835:1877	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	10	40	theme	similar	1837:1843	arg1	response					1845:1852	a similar response	1835:1852	a similar response to histotripsy treatment	1835:1877	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	5	41	theme	repetition	1038:1047	arg1	frequencies					1049:1059	different pulse repetition frequencies	1022:1059	different pulse repetition frequencies	1022:1059	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	10	42	dep	useful	1899:1904	arg1	cost-effective					1906:1919	cost-effective	1906:1919	cost-effective	1906:1919	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	3	43	theme	pathologic	477:486	arg1	tissue					496:501	pathologic fibrous tissue	477:501	pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy	477:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	5	44	theme	700-kHz	988:994	arg1	transducer					1008:1017	a 700-kHz histotripsy transducer	986:1017	a 700-kHz histotripsy transducer	986:1017	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	6	45	theme	differential	1127:1138	arg1	reduction					1140:1148	differential reduction	1127:1148	differential reduction in stiffness	1127:1161	Post-treatment, the hybrid gels and the tissue samples exhibited differential reduction in stiffness as measured by SWE.					
35697582	4	46	theme	indentometry	801:812	arg1	techniques					814:823	shear wave elastography (SWE) and indentometry techniques	767:823	techniques	814:823	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	3	47	theme	prostate	519:526	arg1	BPH					541:543	BPH	541:543	BPH	541:543	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	47	theme	prostate	519:526	arg1	hyperplasia					528:538	benign prostate hyperplasia	512:538	benign prostate hyperplasia (BPH)	512:544	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	7	48	theme	liquified	1273:1281	arg1	areas					1283:1287	fully liquified areas	1267:1287	fully liquified areas	1267:1287	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	3	49	theme	polyacrylamide	702:715	arg1	that					682:685	that	682:685	that	682:685	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	49	theme	polyacrylamide	702:715	arg1	hybrid					692:697	a hybrid	690:697	a hybrid of polyacrylamide and alginate	690:728	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	2	50	theme	tissues	372:378	arg1	variety					356:362	a variety	354:362	a variety of soft tissues	354:378	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	50	theme	tissues	372:378	arg1	tissues					372:378	soft tissues	367:378	soft tissues	367:378	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	4	51	theme	human	863:867	arg1	tissue					890:895	human BPH ex vivo prostate tissue	863:895	human BPH ex vivo prostate tissue	863:895	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	9	52	theme	higher	1670:1675	arg1	modulus					1685:1691	comparable or higher Young's modulus	1656:1691	comparable or higher Young's modulus	1656:1691	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	5	53	dep	ex	941:942	arg1	vivo					944:947	vivo	944:947	vivo	944:947	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	10	54	theme	developed	1742:1750	arg1	hydrogels					1752:1760	the developed hydrogels	1738:1760	the developed hydrogels	1738:1760	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	3	55	theme	alginate	721:728	arg1	that					682:685	that	682:685	that	682:685	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	55	theme	alginate	721:728	arg1	hybrid					692:697	a hybrid	690:697	a hybrid of polyacrylamide and alginate	690:728	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	1	56	theme	immediate	201:209	arg1	feedback					211:218	immediate feedback	201:218	immediate feedback	201:218	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	10	57	theme	treatment	1973:1981	arg1	protocols					1983:1991	different treatment protocols	1963:1991	different treatment protocols	1963:1991	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	3	58	theme	other	550:554	arg1	diseases					556:563	other diseases	550:563	other diseases that are potentially treatable with histotripsy	550:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	5	59	theme	Different	898:906	arg1	compositions					916:927	Different phantom compositions	898:927	Different phantom compositions	898:927	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	10	60	dep	ex	1811:1812	arg1	vivo					1814:1817	vivo	1814:1817	vivo	1814:1817	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	10	61	theme	prostate	1802:1809	arg1	tissue					1819:1824	BPH prostate ex vivo tissue	1798:1824	BPH prostate ex vivo tissue	1798:1824	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	5	62	theme	phantom	908:914	arg1	compositions					916:927	Different phantom compositions	898:927	Different phantom compositions	898:927	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	4	63	theme	prostate	881:888	arg1	tissue					890:895	human BPH ex vivo prostate tissue	863:895	human BPH ex vivo prostate tissue	863:895	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	1	64	theme	cost-effective	129:142	arg1	medium					144:149	a cost-effective medium	127:149	a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback	127:218	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	8	65	theme	contrast	1316:1323	arg1	microscopy					1325:1334	Phase contrast microscopy	1310:1334	Phase contrast microscopy of the gel samples	1310:1353	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	4	66	theme	ex	873:874	arg1	tissue					890:895	human BPH ex vivo prostate tissue	863:895	human BPH ex vivo prostate tissue	863:895	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	10	67	located	found	1789:1793	arg2	elasticities					1776:1787	elasticities	1776:1787	elasticities found in BPH prostate ex vivo tissue	1776:1824	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	10	67	located	found	1789:1793	arg1	tissue					1819:1824	BPH prostate ex vivo tissue	1798:1824	BPH prostate ex vivo tissue	1798:1824	These results indicate that the developed hydrogels closely mimic elasticities found in BPH prostate ex vivo tissue and have a similar response to histotripsy treatment, thus making them a useful cost-effective alternative for developing and evaluating different treatment protocols.					
35697582	7	68	attach	present	1234:1240	arg2	areas					1223:1227	partially treated areas	1205:1227	partially treated areas	1205:1227	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	7	68	attach	present	1234:1240	arg1	ultrasound					1193:1202	B-mode ultrasound	1186:1202	B-mode ultrasound	1186:1202	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	9	69	dep	ex	1605:1606	arg1	vivo					1608:1611	vivo	1608:1611	vivo	1608:1611	The dose required to achieve liquefaction in the hybrid gel was similar to what has been observed in ex vivo tissue and greater than that of agarose of comparable or higher Young's modulus by a factor >10.					
35697582	0	70	theme	Ultrasound	75:84	arg1	Therapies					86:94	Focused Ultrasound Therapies	67:94	Focused Ultrasound Therapies	67:94	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	1	71	theme	histotripsy	163:173	arg1	parameters					185:194	histotripsy treatment parameters	163:194	histotripsy treatment parameters with immediate feedback	163:218	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	8	72	theme	gel	1343:1345	arg1	samples					1347:1353	the gel samples	1339:1353	the gel samples	1339:1353	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	7	73	theme	treated	1215:1221	arg1	areas					1223:1227	partially treated areas	1205:1227	partially treated areas	1205:1227	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	4	74	theme	shear	767:771	arg1	SWE					792:794	shear wave elastography (SWE) and indentometry techniques	767:823	SWE	792:794	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	8	75	with	consistent	1388:1397	arg1	dimensions					1422:1431	the target lesion dimensions	1404:1431	the target lesion dimensions	1404:1431	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	4	76	theme	elastography	778:789	arg1	SWE					792:794	shear wave elastography (SWE) and indentometry techniques	767:823	SWE	792:794	The stiffness was established using shear wave elastography (SWE) and indentometry techniques and was found to be representative of human BPH ex vivo prostate tissue.					
35697582	7	77	theme	B-mode	1186:1191	arg1	ultrasound					1193:1202	B-mode ultrasound	1186:1202	B-mode ultrasound	1186:1202	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	5	78	theme	ex	941:942	arg1	samples					960:966	excised ex vivo BPH tissue samples	933:966	excised ex vivo BPH tissue samples	933:966	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	6	79	theme	hybrid	1082:1087	arg1	gels					1089:1092	the hybrid gels	1078:1092	the hybrid gels	1078:1092	Post-treatment, the hybrid gels and the tissue samples exhibited differential reduction in stiffness as measured by SWE.					
35697582	2	80	theme	fibrous	441:447	arg1	tissue					460:465	fibrous connective tissue	441:465	fibrous connective tissue	441:465	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	8	81	theme	consistent	1388:1397	arg1	regions					1380:1386	regions	1380:1386	regions consistent with the target lesion dimensions	1380:1431	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	0	82	theme	Hydrogel	21:28	arg1	Phantoms					30:37	Tough Hydrogel Phantoms	15:37	Tough Hydrogel Phantoms	15:37	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	5	83	theme	BPH	949:951	arg1	samples					960:966	excised ex vivo BPH tissue samples	933:966	excised ex vivo BPH tissue samples	933:966	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	3	84	theme	high	653:656	arg1	toughness					658:666	high toughness	653:666	high toughness	653:666	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	8	85	theme	lesion	1415:1420	arg1	dimensions					1422:1431	the target lesion dimensions	1404:1431	the target lesion dimensions	1404:1431	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	6	86	from	reduction	1140:1148	arg1	stiffness					1153:1161	stiffness	1153:1161	stiffness	1153:1161	Post-treatment, the hybrid gels and the tissue samples exhibited differential reduction in stiffness as measured by SWE.					
35697582	2	87	theme	high	405:408	arg1	toughness					410:418	high toughness	405:418	high toughness	405:418	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	87	theme	high	405:408	arg1	characteristic					423:436	a characteristic	421:436	a characteristic of fibrous connective tissue	421:465	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	0	88	theme	Fibrous	48:54	arg1	Tissue					56:61	Fibrous Tissue	48:61	Fibrous Tissue for Focused Ultrasound Therapies	48:94	Development of Tough Hydrogel Phantoms to Mimic Fibrous Tissue for Focused Ultrasound Therapies.					
35697582	5	89	theme	pulse	1032:1036	arg1	frequencies					1049:1059	different pulse repetition frequencies	1022:1059	different pulse repetition frequencies	1022:1059	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	7	90	theme	hypoechoic	1292:1301	arg1	zones					1303:1307	hypoechoic zones	1292:1307	hypoechoic zones	1292:1307	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	2	91	theme	tissue	460:465	arg1	toughness					410:418	high toughness	405:418	high toughness	405:418	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	91	theme	tissue	460:465	arg1	characteristic					423:436	a characteristic	421:436	a characteristic of fibrous connective tissue	421:465	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	92	theme	polyacrylamide	233:246	arg1	gels					248:251	Agarose and polyacrylamide gels	221:251	gels	248:251	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	3	93	theme	benign	512:517	arg1	BPH					541:543	BPH	541:543	BPH	541:543	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	3	93	theme	benign	512:517	arg1	hyperplasia					528:538	benign prostate hyperplasia	512:538	benign prostate hyperplasia (BPH)	512:544	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	2	94	theme	variety	356:362	arg1	properties					326:335	acoustic properties	317:335	acoustic properties	317:335	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	2	94	theme	variety	356:362	arg1	stiffness					341:349	stiffness	341:349	stiffness	341:349	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	1	95	with	parameters	185:194	arg1	feedback					211:218	immediate feedback	201:218	immediate feedback	201:218	Tissue-mimicking gels provide a cost-effective medium to optimize histotripsy treatment parameters with immediate feedback.					
35697582	2	96	theme	Agarose	221:227	arg1	gels					248:251	Agarose and polyacrylamide gels	221:251	gels	248:251	Agarose and polyacrylamide gels are often used to evaluate treatment outcomes as they mimic the acoustic properties and stiffness of a variety of soft tissues, but they do not exhibit high toughness, a characteristic of fibrous connective tissue.					
35697582	3	97	theme	fibrous	488:494	arg1	tissue					496:501	pathologic fibrous tissue	477:501	pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy	477:611	To mimic pathologic fibrous tissue found in benign prostate hyperplasia (BPH) and other diseases that are potentially treatable with histotripsy, an optically transparent hydrogel with high toughness was developed that is a hybrid of polyacrylamide and alginate.					
35697582	8	98	from	liquefaction	1364:1375	arg1	regions					1380:1386	regions	1380:1386	regions consistent with the target lesion dimensions	1380:1431	Phase contrast microscopy of the gel samples revealed liquefaction in regions consistent with the target lesion dimensions and correlated to findings identified in tissue samples via histology.					
35697582	5	99	theme	histotripsy	996:1006	arg1	transducer					1008:1017	a 700-kHz histotripsy transducer	986:1017	a 700-kHz histotripsy transducer	986:1017	Different phantom compositions and excised ex vivo BPH tissue samples were treated with a 700-kHz histotripsy transducer at different pulse repetition frequencies.					
35697582	7	100	located	present	1234:1240	arg2	areas					1223:1227	partially treated areas	1205:1227	partially treated areas	1205:1227	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
35697582	7	100	located	present	1234:1240	arg1	ultrasound					1193:1202	B-mode ultrasound	1186:1202	B-mode ultrasound	1186:1202	On B-mode ultrasound, partially treated areas were present as hyperechoic zones and fully liquified areas as hypoechoic zones.					
36208556	1	0	from	supplement	337:346	arg1	fluid					359:363	gastric fluid	351:363	gastric fluid	351:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	5	1	theme	electrode	991:999	arg1	performances					1001:1012	electrode performances	991:1012	electrode performances	991:1012	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	0	2	theme	iron	156:159	arg1	supplement					161:170	iron supplement	156:170	iron supplement in simulated gastric fluid	156:197	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	1	3	theme	Fe	240:241	arg1	determination					223:235	Simultaneous selective determination	200:235	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ)	200:256	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	0	4	theme	selective	93:101	arg1	determination					103:115	simultaneous selective determination	80:115	simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ)	80:134	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	3	5	theme	carbon	575:580	arg1	N-CQDs					596:601	N-CQDs	596:601	N-CQDs	596:601	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	3	5	theme	carbon	575:580	arg1	dots					590:593	nitrogen-doped carbon quantum dots	560:593	nitrogen-doped carbon quantum dots (N-CQDs)	560:602	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	4	6	theme	glassy	777:782	arg1	GCE					802:804	GCE	802:804	GCE	802:804	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	4	6	theme	glassy	777:782	arg1	electrode					791:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode	750:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE)	750:805	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	4	7	theme	modified	768:775	arg1	GCE					802:804	GCE	802:804	GCE	802:804	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	4	7	theme	modified	768:775	arg1	electrode					791:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode	750:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE)	750:805	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	0	8	theme	Fe	120:121	arg1	determination					103:115	simultaneous selective determination	80:115	simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ)	80:134	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	4	9	theme	carbon	784:789	arg1	GCE					802:804	GCE	802:804	GCE	802:804	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	4	9	theme	carbon	784:789	arg1	electrode					791:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode	750:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE)	750:805	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	3	10	theme	various	460:466	arg1	characterizations					468:484	The various characterizations	456:484	The various characterizations	456:484	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	6	11	theme	differential	1141:1152	arg1	DPV					1173:1175	DPV	1173:1175	DPV	1173:1175	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	11	theme	differential	1141:1152	arg1	voltammetry					1160:1170	differential pulse voltammetry	1141:1170	differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF)	1141:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	0	12	from	supplement	161:170	arg1	fluid					193:197	simulated gastric fluid	175:197	simulated gastric fluid	175:197	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	1	13	theme	iron	299:302	arg1	study					290:294	the study	286:294	the study of iron ion tracking and release of iron supplement in gastric fluid	286:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	0	14	theme	gastric	185:191	arg1	fluid					193:197	simulated gastric fluid	175:197	simulated gastric fluid	175:197	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	6	15	theme	simulated	1244:1252	arg1	SGF					1269:1271	SGF	1269:1271	SGF	1269:1271	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	15	theme	simulated	1244:1252	arg1	fluid					1262:1266	simulated gastric fluid	1244:1266	simulated gastric fluid (SGF)	1244:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	1	16	from	release	321:327	arg1	fluid					359:363	gastric fluid	351:363	gastric fluid	351:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	1	17	theme	ion	304:306	arg1	tracking					308:315	ion tracking	304:315	ion tracking	304:315	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	0	18	theme	simulated	175:183	arg1	fluid					193:197	simulated gastric fluid	175:197	simulated gastric fluid	175:197	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	2	19	theme	composite	383:391	arg1	N-CQDs/AgNPs/β-CD					403:419	N-CQDs/AgNPs/β-CD	403:419	N-CQDs/AgNPs/β-CD	403:419	In this paper, a composite material (N-CQDs/AgNPs/β-CD) was prepared by a one-pot method.					
36208556	2	19	theme	composite	383:391	arg1	material					393:400	a composite material	381:400	a composite material (N-CQDs/AgNPs/β-CD)	381:420	In this paper, a composite material (N-CQDs/AgNPs/β-CD) was prepared by a one-pot method.					
36208556	6	20	theme	iron	1219:1222	arg1	supplementations					1224:1239	four iron supplementations	1214:1239	four iron supplementations in simulated gastric fluid (SGF)	1214:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	0	21	theme	Electrochemical	0:14	arg1	sensor					16:21	Electrochemical sensor	0:21	Electrochemical sensor	0:21	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	5	22	theme	impedance	912:920	arg1	EIS					936:938	EIS	936:938	EIS	936:938	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	5	22	theme	impedance	912:920	arg1	spectroscopy					922:933	electrochemical impedance spectroscopy	896:933	electrochemical impedance spectroscopy (EIS)	896:939	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	6	23	attach	released	1200:1207	arg2	DPV					1173:1175	DPV	1173:1175	DPV	1173:1175	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	23	attach	released	1200:1207	arg1	supplementations					1224:1239	four iron supplementations	1214:1239	four iron supplementations in simulated gastric fluid (SGF)	1214:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	23	attach	released	1200:1207	arg2	voltammetry					1160:1170	differential pulse voltammetry	1141:1170	differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF)	1141:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	3	24	theme	dots	590:593	arg1	surface					549:555	the surface	545:555	the surface of nitrogen-doped carbon quantum dots (N-CQDs)	545:602	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	5	25	theme	electrochemical	896:910	arg1	EIS					936:938	EIS	936:938	EIS	936:938	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	5	25	theme	electrochemical	896:910	arg1	spectroscopy					922:933	electrochemical impedance spectroscopy	896:933	electrochemical impedance spectroscopy (EIS)	896:939	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	3	26	theme	nitrogen-doped	560:573	arg1	N-CQDs					596:601	N-CQDs	596:601	N-CQDs	596:601	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	3	26	theme	nitrogen-doped	560:573	arg1	dots					590:593	nitrogen-doped carbon quantum dots	560:593	nitrogen-doped carbon quantum dots (N-CQDs)	560:602	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	1	27	theme	Fe	251:252	arg1	determination					223:235	Simultaneous selective determination	200:235	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ)	200:256	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	6	28	theme	Fe	1192:1193	arg1	DPV					1173:1175	DPV	1173:1175	DPV	1173:1175	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	28	theme	Fe	1192:1193	arg1	voltammetry					1160:1170	differential pulse voltammetry	1141:1170	differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF)	1141:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	4	29	theme	N-CQDs/AgNPs/β-CD	750:766	arg1	GCE					802:804	GCE	802:804	GCE	802:804	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	4	29	theme	N-CQDs/AgNPs/β-CD	750:766	arg1	electrode					791:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode	750:799	N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE)	750:805	Then, N-CQDs/AgNPs/β-CD modified glassy carbon electrode (GCE) was applied to detect Fe(II) and Fe(III) simultaneously.					
36208556	1	30	from	iron	299:302	arg1	fluid					359:363	gastric fluid	351:363	gastric fluid	351:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	5	31	theme	spectroscopy	922:933	arg1	results					941:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results	864:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results	864:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	6	32	theme	gastric	1254:1260	arg1	SGF					1269:1271	SGF	1269:1271	SGF	1269:1271	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	32	theme	gastric	1254:1260	arg1	fluid					1262:1266	simulated gastric fluid	1244:1266	simulated gastric fluid (SGF)	1244:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	1	33	theme	release	321:327	arg1	study					290:294	the study	286:294	the study of iron ion tracking and release of iron supplement in gastric fluid	286:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	5	34	theme	cyclic	868:873	arg1	voltammetry					875:885	The cyclic voltammetry	864:885	The cyclic voltammetry (CV)	864:890	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	5	34	theme	cyclic	868:873	arg1	CV					888:889	CV	888:889	CV	888:889	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	3	35	theme	silver	500:505	arg1	AgNPs					522:526	AgNPs	522:526	AgNPs	522:526	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	3	35	theme	silver	500:505	arg1	nanoparticles					507:519	the silver nanoparticles	496:519	the silver nanoparticles (AgNPs)	496:527	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	0	36	theme	N-CQDs/AgNPs/β-CD	32:48	arg1	nanomaterials					50:62	N-CQDs/AgNPs/β-CD nanomaterials	32:62	N-CQDs/AgNPs/β-CD nanomaterials	32:62	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	3	37	theme	Ag-O	664:667	arg1	bonds					669:673	Ag-O bonds	664:673	Ag-O bonds	664:673	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	0	38	theme	Fe	130:131	arg1	determination					103:115	simultaneous selective determination	80:115	simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ)	80:134	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	5	39	theme	voltammetry	875:885	arg1	results					941:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results	864:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results	864:947	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	1	40	dep	iron	299:302	arg1	tracking					308:315	ion tracking	304:315	ion tracking	304:315	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	2	41	theme	one-pot	440:446	arg1	method					448:453	a one-pot method	438:453	a one-pot method	438:453	In this paper, a composite material (N-CQDs/AgNPs/β-CD) was prepared by a one-pot method.					
36208556	6	42	theme	Fe	1181:1182	arg1	DPV					1173:1175	DPV	1173:1175	DPV	1173:1175	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	42	theme	Fe	1181:1182	arg1	voltammetry					1160:1170	differential pulse voltammetry	1141:1170	differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF)	1141:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	1	43	theme	iron	332:335	arg1	supplement					337:346	iron supplement	332:346	iron supplement in gastric fluid	332:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	5	44	theme	synergistic	1029:1039	arg1	effect					1041:1046	the synergistic effect	1025:1046	the synergistic effect between N-CQDs, AgNPs and β-CD	1025:1077	The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results confirmed that N-CQDs/AgNPs/β-CD enhanced electrode performances because of the synergistic effect between N-CQDs, AgNPs and β-CD.					
36208556	1	45	theme	supplement	337:346	arg1	iron					299:302	iron ion tracking and release of iron supplement in gastric fluid	299:363	iron	299:302	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	1	45	theme	supplement	337:346	arg1	release					321:327	release	321:327	release of iron supplement in gastric fluid	321:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	0	46	dep	irons	136:140	arg1	released					142:149	released	142:149	irons released from iron supplement in simulated gastric fluid	136:197	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	1	47	theme	great	264:268	arg1	significance					270:281	great significance	264:281	great significance	264:281	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	6	48	from	supplementations	1224:1239	arg1	SGF					1269:1271	SGF	1269:1271	SGF	1269:1271	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	48	from	supplementations	1224:1239	arg1	fluid					1262:1266	simulated gastric fluid	1244:1266	simulated gastric fluid (SGF)	1244:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	1	49	theme	Simultaneous	200:211	arg1	determination					223:235	Simultaneous selective determination	200:235	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ)	200:256	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	3	50	from	nanoparticles	704:716	arg1	surface					725:731	the surface	721:731	the surface of N-CQDs	721:741	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	1	51	theme	gastric	351:357	arg1	fluid					359:363	gastric fluid	351:363	gastric fluid	351:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	3	52	dep	confirmed	486:494	arg1	grew					529:532	grew	529:532	confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs)	486:602	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	3	53	theme	N-CQDs	736:741	arg1	surface					725:731	the surface	721:731	the surface of N-CQDs	721:741	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	1	54	theme	selective	213:221	arg1	determination					223:235	Simultaneous selective determination	200:235	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ)	200:256	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	0	55	theme	simultaneous	80:91	arg1	determination					103:115	simultaneous selective determination	80:115	simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ)	80:134	Electrochemical sensor based on N-CQDs/AgNPs/β-CD nanomaterials: Application to simultaneous selective determination of Fe(Ⅱ) and Fe(Ⅲ) irons released from iron supplement in simulated gastric fluid.					
36208556	3	56	theme	quantum	582:588	arg1	N-CQDs					596:601	N-CQDs	596:601	N-CQDs	596:601	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	3	56	theme	quantum	582:588	arg1	dots					590:593	nitrogen-doped carbon quantum dots	560:593	nitrogen-doped carbon quantum dots (N-CQDs)	560:602	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	1	57	from	fluid	359:363	arg1	iron					299:302	iron ion tracking and release of iron supplement in gastric fluid	299:363	iron	299:302	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	1	57	from	fluid	359:363	arg1	release					321:327	release	321:327	release of iron supplement in gastric fluid	321:363	Simultaneous selective determination of Fe (Ⅱ) and Fe (Ⅲ) is of great significance to the study of iron ion tracking and release of iron supplement in gastric fluid.					
36208556	3	58	theme	gourd-like	693:702	arg1	nanoparticles					704:716	gourd-like nanoparticles	693:716	gourd-like nanoparticles on the surface of N-CQDs	693:741	The various characterizations confirmed the silver nanoparticles (AgNPs) grew in situ on the surface of nitrogen-doped carbon quantum dots (N-CQDs), and the β-cyclodextrin (β-CD) and AgNPs linked together by Ag-O bonds finally presented gourd-like nanoparticles on the surface of N-CQDs.					
36208556	6	59	theme	pulse	1154:1158	arg1	DPV					1173:1175	DPV	1173:1175	DPV	1173:1175	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36208556	6	59	theme	pulse	1154:1158	arg1	voltammetry					1160:1170	differential pulse voltammetry	1141:1170	differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF)	1141:1272	The sensor was successfully applied for the determination by differential pulse voltammetry (DPV) of Fe(II) and Fe(III) released from four iron supplementations in simulated gastric fluid (SGF).					
36737178	2	0	contain	having	377:382	arg1	macrospheres					364:375	newly engineered chitosan macrospheres	338:375	newly engineered chitosan macrospheres having interconnected and interlaced network pores	338:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	0	contain	having	377:382	arg2	pores					422:426	interconnected and interlaced network pores	384:426	interconnected and interlaced network pores	384:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	0	contain	having	377:382	arg1	host					493:496	novel host	487:496	novel host for the effective immobilization of alkaline protease	487:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	4	1	theme	%	971:971	arg1	recovery					954:961	ultra-high activity recovery	934:961	ultra-high activity recovery of 92.4 % for alkaline protease	934:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	4	1	theme	%	971:971	arg1	43.8 ± 0.8 mg/g					914:928	43.8 ± 0.8 mg/g	914:928	43.8 ± 0.8 mg/g	914:928	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	3	2	theme	chitosan	691:698	arg1	chains					700:705	chitosan chains	691:705	chitosan chains	691:705	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	2	3	theme	network	414:420	arg1	pores					422:426	interconnected and interlaced network pores	384:426	interconnected and interlaced network pores	384:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	5	4	theme	structural	1044:1053	arg1	conformation					1055:1066	the structural conformation	1040:1066	the structural conformation of alkaline protease from inactivation	1040:1105	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	2	5	theme	protease	543:550	arg1	immobilization					516:529	the effective immobilization	502:529	the effective immobilization of alkaline protease	502:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	6	theme	interlaced	403:412	arg1	pores					422:426	interconnected and interlaced network pores	384:426	interconnected and interlaced network pores	384:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	0	7	theme	protease	97:104	arg1	immobilization					106:119	alkaline protease immobilization	88:119	alkaline protease immobilization with high activity and stability	88:152	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	4	8	theme	alkaline	977:984	arg1	protease					986:993	alkaline protease	977:993	alkaline protease	977:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	3	9	theme	pore-forming	609:620	arg1	agents					622:627	gas-induced pore-forming agents	597:627	gas-induced pore-forming agents	597:627	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	7	10	theme	widespread	1540:1549	arg1	utilization					1551:1561	widespread utilization	1540:1561	widespread utilization in various practical applications	1540:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	0	11	theme	alkaline	88:95	arg1	immobilization					106:119	alkaline protease immobilization	88:119	alkaline protease immobilization with high activity and stability	88:152	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	4	12	theme	as-developed	841:852	arg1	P2CSM					869:873	the as-developed porous support P2CSM	837:873	the as-developed porous support P2CSM	837:873	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	3	13	theme	agents	622:627	arg1	effect					568:573	The synergetic effect	553:573	The synergetic effect of SiO2 templates and gas-induced pore-forming agents	553:627	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	6	14	theme	free	1284:1287	arg1	protease					1298:1305	free alkaline protease	1284:1305	free alkaline protease	1284:1305	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	4	15	theme	activity	945:952	arg1	recovery					954:961	ultra-high activity recovery	934:961	ultra-high activity recovery of 92.4 % for alkaline protease	934:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	5	16	from	inactivation	1094:1105	arg1	conformation					1055:1066	the structural conformation	1040:1066	the structural conformation of alkaline protease from inactivation	1040:1105	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	7	17	theme	various	1566:1572	arg1	applications					1584:1595	various practical applications	1566:1595	various practical applications	1566:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	1	18	theme	enzymatic	187:195	arg1	Fabrication					155:165	Fabrication	155:165	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties	155:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	2	19	theme	effective	506:514	arg1	immobilization					516:529	the effective immobilization	502:529	the effective immobilization of alkaline protease	502:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	4	20	theme	ultra-high	934:943	arg1	recovery					954:961	ultra-high activity recovery	934:961	ultra-high activity recovery of 92.4 % for alkaline protease	934:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	3	21	theme	gas-induced	597:607	arg1	agents					622:627	gas-induced pore-forming agents	597:627	gas-induced pore-forming agents	597:627	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	6	22	theme	structural	1226:1235	arg1	stability					1237:1245	remarkably better structural stability	1208:1245	remarkably better structural stability	1208:1245	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	2	23	theme	dual	445:448	arg1	strategy					463:470	dual pore-forming strategy	445:470	dual pore-forming strategy	445:470	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	7	24	theme	highly-active	1504:1516	arg1	enzyme-composites					1518:1534	highly-active enzyme-composites	1504:1534	highly-active enzyme-composites for widespread utilization in various practical applications	1504:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	6	25	theme	P2CSM	1388:1392	arg1	activity					1367:1374	the residual activity	1354:1374	the residual activity of Protease@P2CSM	1354:1392	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	0	26	with	immobilization	106:119	arg1	stability					144:152	stability	144:152	stability	144:152	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	0	26	with	immobilization	106:119	arg1	activity					131:138	high activity	126:138	high activity	126:138	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	2	27	theme	chitosan	355:362	arg1	macrospheres					364:375	newly engineered chitosan macrospheres	338:375	newly engineered chitosan macrospheres having interconnected and interlaced network pores	338:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	27	theme	chitosan	355:362	arg1	host					493:496	novel host	487:496	novel host for the effective immobilization of alkaline protease	487:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	1	28	theme	enzymatic	305:313	arg1	bio-catalysis					315:327	enzymatic bio-catalysis	305:327	enzymatic bio-catalysis	305:327	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	4	29	theme	recovery	954:961	arg1	capacity					902:909	a maximum loading capacity	884:909	a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease	884:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	2	30	theme	engineered	344:353	arg1	macrospheres					364:375	newly engineered chitosan macrospheres	338:375	newly engineered chitosan macrospheres having interconnected and interlaced network pores	338:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	30	theme	engineered	344:353	arg1	host					493:496	novel host	487:496	novel host for the effective immobilization of alkaline protease	487:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	1	31	theme	excellent	213:221	arg1	affinity					223:230	excellent affinity	213:230	excellent affinity to enzymes and superior mass transfer properties	213:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	0	32	theme	chitosan	23:30	arg1	Construction					0:11	Construction	0:11	Construction of porous chitosan	0:30	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	4	33	theme	binding	822:828	arg1	sites					830:834	abundant available binding sites	803:834	abundant available binding sites	803:834	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	5	34	theme	flexible	1119:1126	arg1	interaction					1137:1147	the flexible covalent interaction	1115:1147	the flexible covalent interaction	1115:1147	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	6	35	theme	residual	1358:1365	arg1	activity					1367:1374	the residual activity	1354:1374	the residual activity of Protease@P2CSM	1354:1392	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	4	36	theme	exposed	783:789	arg1	surface					791:797	the highly exposed surface	772:797	the highly exposed surface	772:797	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	6	37	theme	Protease	1379:1386	arg1	P2CSM					1388:1392	Protease@P2CSM	1379:1392	Protease@P2CSM	1379:1392	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	5	38	theme	alkaline	1071:1078	arg1	protease					1080:1087	alkaline protease	1071:1087	alkaline protease	1071:1087	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	0	39	theme	porous	16:21	arg1	chitosan					23:30	porous chitosan	16:30	porous chitosan	16:30	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	0	40	theme	high	126:129	arg1	activity					131:138	high activity	126:138	high activity	126:138	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	6	41	theme	proteolytic	1329:1339	arg1	ability					1341:1347	excellent proteolytic ability	1319:1347	excellent proteolytic ability	1319:1347	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	6	42	theme	alkaline	1289:1296	arg1	protease					1298:1305	free alkaline protease	1284:1305	free alkaline protease	1284:1305	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	5	43	theme	protease	1080:1087	arg1	conformation					1055:1066	the structural conformation	1040:1066	the structural conformation of alkaline protease from inactivation	1040:1105	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	2	44	theme	alkaline	534:541	arg1	protease					543:550	alkaline protease	534:550	alkaline protease	534:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	3	45	theme	synergetic	557:566	arg1	effect					568:573	The synergetic effect	553:573	The synergetic effect of SiO2 templates and gas-induced pore-forming agents	553:627	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	1	46	contain	having	206:211	arg1	enzymatic					187:195	enzymatic	187:195	enzymatic	187:195	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	1	46	contain	having	206:211	arg2	affinity					223:230	excellent affinity	213:230	excellent affinity to enzymes and superior mass transfer properties	213:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	4	47	theme	maximum	886:892	arg1	capacity					902:909	a maximum loading capacity	884:909	a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease	884:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	2	48	theme	pore-forming	450:461	arg1	strategy					463:470	dual pore-forming strategy	445:470	dual pore-forming strategy	445:470	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	6	49	theme	better	1219:1224	arg1	stability					1237:1245	remarkably better structural stability	1208:1245	remarkably better structural stability	1208:1245	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	6	50	theme	Protease	1180:1187	arg1	P2CSM					1189:1193	Protease@P2CSM	1180:1193	Protease@P2CSM	1180:1193	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	0	51	theme	pore-forming	54:65	arg1	strategy					67:74	dual pore-forming strategy	49:74	dual pore-forming strategy	49:74	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	6	52	theme	consecutive	1433:1443	arg1	reuses					1445:1450	7 consecutive reuses	1431:1450	7 consecutive reuses	1431:1450	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	5	53	theme	covalent	1128:1135	arg1	interaction					1137:1147	the flexible covalent interaction	1115:1147	the flexible covalent interaction	1115:1147	P2CSM is competent to effectively stabilize the structural conformation of alkaline protease from inactivation through the flexible covalent interaction.					
36737178	1	54	dep	enzymatic	187:195	arg1	supports					197:204	supports	197:204	supports	197:204	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	6	55	theme	@	1387:1387	arg1	P2CSM					1388:1392	Protease@P2CSM	1379:1392	Protease@P2CSM	1379:1392	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	0	56	theme	dual	49:52	arg1	strategy					67:74	dual pore-forming strategy	49:74	dual pore-forming strategy	49:74	Construction of porous chitosan macrospheres via dual pore-forming strategy as host for alkaline protease immobilization with high activity and stability.					
36737178	6	57	theme	excellent	1319:1327	arg1	ability					1341:1347	excellent proteolytic ability	1319:1347	excellent proteolytic ability	1319:1347	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	4	58	theme	43.8 ± 0.8 mg/g	914:928	arg1	capacity					902:909	a maximum loading capacity	884:909	a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease	884:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	2	59	theme	interconnected	384:397	arg1	pores					422:426	interconnected and interlaced network pores	384:426	interconnected and interlaced network pores	384:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	3	60	theme	important	637:645	arg1	role					647:650	an important role	634:650	an important role	634:650	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	7	61	theme	practical	1574:1582	arg1	applications					1584:1595	various practical applications	1566:1595	various practical applications	1566:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	7	62	theme	promising	1474:1482	arg1	avenue					1484:1489	a promising avenue	1472:1489	a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications	1472:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	3	63	theme	chains	700:705	arg1	over-crosslinking					670:686	the over-crosslinking	666:686	the over-crosslinking of chitosan chains	666:705	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	4	64	theme	available	812:820	arg1	sites					830:834	abundant available binding sites	803:834	abundant available binding sites	803:834	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	1	65	theme	superior	247:254	arg1	properties					270:279	superior mass transfer properties	247:279	superior mass transfer properties	247:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	4	66	theme	support	861:867	arg1	P2CSM					869:873	the as-developed porous support P2CSM	837:873	the as-developed porous support P2CSM	837:873	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	3	67	theme	interior	738:745	arg1	porosity					747:754	interior porosity	738:754	interior porosity	738:754	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	4	68	theme	porous	854:859	arg1	P2CSM					869:873	the as-developed porous support P2CSM	837:873	the as-developed porous support P2CSM	837:873	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	4	69	theme	abundant	803:810	arg1	sites					830:834	abundant available binding sites	803:834	abundant available binding sites	803:834	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	7	70	from	utilization	1551:1561	arg1	applications					1584:1595	various practical applications	1566:1595	various practical applications	1566:1595	This work provides a promising avenue to construct highly-active enzyme-composites for widespread utilization in various practical applications.					
36737178	1	71	theme	mass	256:259	arg1	properties					270:279	superior mass transfer properties	247:279	superior mass transfer properties	247:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	3	72	theme	porosity	747:754	arg1	elevation					725:733	the elevation	721:733	the elevation of interior porosity	721:754	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	4	73	theme	loading	894:900	arg1	capacity					902:909	a maximum loading capacity	884:909	a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease	884:993	Benefited from the highly exposed surface and abundant available binding sites, the as-developed porous support P2CSM achieves a maximum loading capacity of 43.8 ± 0.8 mg/g and ultra-high activity recovery of 92.4 % for alkaline protease.					
36737178	6	74	theme	@	1188:1188	arg1	P2CSM					1189:1193	Protease@P2CSM	1180:1193	Protease@P2CSM	1180:1193	Considering these attributes, Protease@P2CSM demonstrates remarkably better structural stability, reusability and SDS-resistance than free alkaline protease, as well as excellent proteolytic ability, and the residual activity of Protease@P2CSM is evaluated as high as 70.3 % after 7 consecutive reuses.					
36737178	3	75	theme	SiO2	578:581	arg1	templates					583:591	SiO2 templates	578:591	SiO2 templates	578:591	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36737178	1	76	theme	transfer	261:268	arg1	properties					270:279	superior mass transfer properties	247:279	superior mass transfer properties	247:279	Fabrication of highly-efficient enzymatic supports having excellent affinity to enzymes and superior mass transfer properties is highly desirable for enzymatic bio-catalysis.					
36737178	2	77	theme	novel	487:491	arg1	macrospheres					364:375	newly engineered chitosan macrospheres	338:375	newly engineered chitosan macrospheres having interconnected and interlaced network pores	338:426	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	2	77	theme	novel	487:491	arg1	host					493:496	novel host	487:496	novel host for the effective immobilization of alkaline protease	487:550	Herein, newly engineered chitosan macrospheres having interconnected and interlaced network pores are prepared via dual pore-forming strategy and applied as novel host for the effective immobilization of alkaline protease.					
36737178	3	78	theme	templates	583:591	arg1	effect					568:573	The synergetic effect	553:573	The synergetic effect of SiO2 templates and gas-induced pore-forming agents	553:627	The synergetic effect of SiO2 templates and gas-induced pore-forming agents play an important role in inhibiting the over-crosslinking of chitosan chains and promoting the elevation of interior porosity.					
36243366	11	0	theme	anti-bacterial	2122:2135	arg1	invasion					2137:2144	anti-bacterial invasion	2122:2144	anti-bacterial invasion	2122:2144	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	8	1	theme	biomaterials	1607:1618	arg1	development					1576:1586	the development	1572:1586	the development of multifunctional biomaterials	1572:1618	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	2	2	theme	wound	377:381	arg1	dressing					383:390	functional wound dressing	366:390	functional wound dressing	366:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	14	3	theme	clinical	2512:2519	arg1	reconstruction					2526:2539	clinical skin reconstruction	2512:2539	clinical skin reconstruction	2512:2539	These results indicated the potential of FHoCP-based hydrogel for application in clinical skin reconstruction.					
36243366	6	4	theme	antibacterial	1195:1207	arg1	effects					1209:1215	antibacterial effects	1195:1215	antibacterial effects	1195:1215	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	10	5	theme	in	1965:1966	arg1	strategy					1982:1989	in situ gelation strategy	1965:1989	in situ gelation strategy	1965:1989	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	2	6	theme	exudate-absorbing	276:292	arg1	matrix					337:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix	266:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing	266:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	11	7	theme	in	2015:2016	arg1	gelation					2023:2030	in situ gelation	2015:2030	in situ gelation	2015:2030	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	14	8	theme	hydrogel	2484:2491	arg1	potential					2459:2467	the potential	2455:2467	the potential of FHoCP-based hydrogel for application in clinical skin reconstruction	2455:2539	These results indicated the potential of FHoCP-based hydrogel for application in clinical skin reconstruction.					
36243366	9	9	theme	excessive	1670:1678	arg1	exudates					1680:1687	excessive exudates	1670:1687	excessive exudates	1670:1687	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	3	10	theme	skeleton	577:584	arg1	material					586:593	the skeleton material	573:593	the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP)	573:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	10	theme	skeleton	577:584	arg1	copolymer					553:561	an innovative metal Fc-HA organic copolymer	519:561	an innovative metal Fc-HA organic copolymer (FHoC)	519:568	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	5	11	theme	composition	879:889	arg1	FHoCP					891:895	the simple composition FHoCP	868:895	the simple composition FHoCP	868:895	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	6	12	theme	fibroblast	1155:1164	arg1	migration					1166:1174	fibroblast migration	1155:1174	fibroblast migration	1155:1174	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	10	13	theme	gelation	1973:1980	arg1	strategy					1982:1989	in situ gelation strategy	1965:1989	in situ gelation strategy	1965:1989	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	0	14	theme	wound	130:134	arg1	healing					136:142	multi-modal wound healing	118:142	multi-modal wound healing	118:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	2	15	theme	exudate-locking	295:309	arg1	matrix					337:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix	266:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing	266:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	1	16	theme	wound	211:215	arg1	management					217:226	slow or non-healing wound management	191:226	slow or non-healing wound management	191:226	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	9	17	theme	stable	1707:1712	arg1	network					1723:1729	stable ECM-like network	1707:1729	stable ECM-like network	1707:1729	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	7	18	theme	chronic	1373:1379	arg1	wounds					1381:1386	chronic wounds	1373:1386	chronic wounds	1373:1386	This study suggested that FHoC biomaterial could accelerate the closure of chronic wounds.					
36243366	8	19	theme	-based	1425:1430	arg1	strategy					1449:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	11	20	dep	in	2015:2016	arg1	situ					2018:2021	situ	2018:2021	situ	2018:2021	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	12	21	theme	hydrophobic	2309:2319	arg1	migration					2344:2352	hydrophobic Fc improved fibroblast migration	2309:2352	hydrophobic Fc improved fibroblast migration	2309:2352	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	6	22	theme	wound	1283:1287	arg1	healing					1289:1295	wound healing	1283:1295	wound healing	1283:1295	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	1	23	theme	Exudate	145:151	arg1	management					153:162	Exudate management	145:162	Exudate management	145:162	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	12	24	theme	improved	2324:2331	arg1	migration					2344:2352	hydrophobic Fc improved fibroblast migration	2309:2352	hydrophobic Fc improved fibroblast migration	2309:2352	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	0	25	theme	organic	61:67	arg1	biomaterial					79:89	ferrocene-hyaluronic acid organic copolymer biomaterial	35:89	ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing	35:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	3	26	theme	metal-organic	405:417	arg1	frameworks					419:428	metal-organic frameworks	405:428	metal-organic frameworks	405:428	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	1	27	from	concern	180:186	arg1	management					217:226	slow or non-healing wound management	191:226	slow or non-healing wound management	191:226	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	9	28	theme	wound	1759:1763	arg1	healing					1765:1771	multimodal wound healing	1748:1771	multimodal wound healing activities	1748:1782	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	12	29	theme	hydrogel	2286:2293	arg1	backbone					2295:2302	the hydrogel backbone	2282:2302	the hydrogel backbone	2282:2302	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	1	30	theme	major	174:178	arg1	concern					180:186	a major concern	172:186	a major concern in slow or non-healing wound management	172:226	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	8	31	theme	solid	1474:1478	arg1	scaffold					1492:1499	a solid drug-loaded scaffold	1472:1499	a solid drug-loaded scaffold	1472:1499	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	5	32	dep	times	913:917	arg1	weight					923:928	its weight	919:928	150 times its weight of water	909:937	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	0	33	theme	exudate	95:101	arg1	management					103:112	exudate management	95:112	exudate management	95:112	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	5	34	theme	anti-bacterial	1086:1099	arg1	invasion					1101:1108	anti-bacterial invasion	1086:1108	anti-bacterial invasion	1086:1108	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	9	35	theme	ideal	1788:1792	arg1	Hydrogels					1648:1656	Hydrogels	1648:1656	Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities	1648:1782	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	9	35	theme	ideal	1788:1792	arg1	dressings					1794:1802	ideal dressings	1788:1802	ideal dressings for accelerating chronic wound contraction	1788:1845	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	5	36	dep	absorbed	900:907	arg1	5					897:897	5	897:897	5	897:897	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	5	37	theme	three-dimensional	961:977	arg1	network					979:985	a firm three-dimensional network	954:985	a firm three-dimensional network	954:985	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	5	37	theme	three-dimensional	961:977	arg1	barrier					1055:1061	a physical barrier	1044:1061	a physical barrier against hemostasis and anti-bacterial invasion	1044:1108	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	7	38	theme	FHoC	1324:1327	arg1	biomaterial					1329:1339	FHoC biomaterial	1324:1339	FHoC biomaterial	1324:1339	This study suggested that FHoC biomaterial could accelerate the closure of chronic wounds.					
36243366	8	39	theme	cell	1505:1508	arg1	therapies					1529:1537	cell or adjunctive drug therapies	1505:1537	therapies	1529:1537	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	4	40	theme	chains	726:731	arg1	rearrangement					701:713	the rearrangement	697:713	the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions	697:791	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	0	41	theme	In	0:1	arg1	strategy					17:24	In situ gelation strategy	0:24	In situ gelation strategy	0:24	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	9	42	theme	chronic	1821:1827	arg1	contraction					1835:1845	chronic wound contraction	1821:1845	chronic wound contraction	1821:1845	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	8	43	theme	adjunctive	1513:1522	arg1	therapies					1529:1537	cell or adjunctive drug therapies	1505:1537	therapies	1529:1537	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	0	44	theme	gelation	8:15	arg1	strategy					17:24	In situ gelation strategy	0:24	In situ gelation strategy	0:24	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	3	45	theme	organic	545:551	arg1	material					586:593	the skeleton material	573:593	the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP)	573:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	45	theme	organic	545:551	arg1	FHoC					564:567	FHoC	564:567	FHoC	564:567	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	45	theme	organic	545:551	arg1	copolymer					553:561	an innovative metal Fc-HA organic copolymer	519:561	an innovative metal Fc-HA organic copolymer (FHoC)	519:568	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	4	46	dep	promoted	688:695	arg1	improved					800:807	improved	800:807	improved hydrogel transition and the exudate-locking ability	800:859	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	8	47	dep	in	1432:1433	arg1	situ					1435:1438	situ	1435:1438	situ	1435:1438	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	5	48	theme	simple	872:877	arg1	FHoCP					891:895	the simple composition FHoCP	868:895	the simple composition FHoCP	868:895	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	5	49	theme	reducing	1009:1016	arg1	inflammation					1018:1029	reducing inflammation	1009:1029	reducing inflammation	1009:1029	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	6	50	dep	Meanwhile	1111:1119	arg1	multi-modal					1122:1132	multi-modal	1122:1132	multi-modal	1122:1132	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	2	51	theme	functional	366:375	arg1	dressing					383:390	functional wound dressing	366:390	functional wound dressing	366:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	0	52	theme	ferrocene-hyaluronic	35:54	arg1	biomaterial					79:89	ferrocene-hyaluronic acid organic copolymer biomaterial	35:89	ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing	35:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	11	53	theme	massive	2161:2167	arg1	exudates					2169:2176	massive exudates	2161:2176	massive exudates	2161:2176	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	8	54	theme	great	1552:1556	arg1	potential					1558:1566	great potential	1552:1566	great potential for the development of multifunctional biomaterials	1552:1618	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	10	55	theme	acid	1909:1912	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	55	theme	acid	1909:1912	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	8	56	theme	unique	1410:1415	arg1	strategy					1449:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	3	57	theme	pre-hydrogel	657:668	arg1	FHoCP					677:681	FHoCP	677:681	FHoCP	677:681	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	57	theme	pre-hydrogel	657:668	arg1	patch					670:674	a pre-hydrogel patch	655:674	a pre-hydrogel patch (FHoCP)	655:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	58	theme	metal	533:537	arg1	material					586:593	the skeleton material	573:593	the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP)	573:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	58	theme	metal	533:537	arg1	FHoC					564:567	FHoC	564:567	FHoC	564:567	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	58	theme	metal	533:537	arg1	copolymer					553:561	an innovative metal Fc-HA organic copolymer	519:561	an innovative metal Fc-HA organic copolymer (FHoC)	519:568	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	0	59	dep	In	0:1	arg1	situ					3:6	situ	3:6	situ	3:6	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	14	60	theme	skin	2521:2524	arg1	reconstruction					2526:2539	clinical skin reconstruction	2512:2539	clinical skin reconstruction	2512:2539	These results indicated the potential of FHoCP-based hydrogel for application in clinical skin reconstruction.					
36243366	9	61	theme	SIGNIFICANCE	1634:1645	arg1	STATEMENT					1621:1629	STATEMENT	1621:1629	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.	1621:1846	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	8	62	theme	multifunctional	1591:1605	arg1	biomaterials					1607:1618	multifunctional biomaterials	1591:1618	multifunctional biomaterials	1591:1618	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	10	63	theme	copolymer	1922:1930	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	63	theme	copolymer	1922:1930	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	12	64	theme	Fc	2321:2322	arg1	migration					2344:2352	hydrophobic Fc improved fibroblast migration	2309:2352	hydrophobic Fc improved fibroblast migration	2309:2352	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	11	65	theme	polymer	2045:2051	arg1	rearrangement					2059:2071	polymer chain rearrangement	2045:2071	polymer chain rearrangement	2045:2071	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	2	66	theme	massive	268:274	arg1	matrix					337:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix	266:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing	266:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	1	67	theme	slow	191:194	arg1	management					217:226	slow or non-healing wound management	191:226	slow or non-healing wound management	191:226	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	4	68	theme	exudate-locking	837:851	arg1	ability					853:859	the exudate-locking ability	833:859	the exudate-locking ability	833:859	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	2	69	theme	stable	316:321	arg1	matrix					337:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix	266:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing	266:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	3	70	dep	in	599:600	arg1	situ					602:605	situ	602:605	situ	602:605	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	1	71	theme	non-healing	199:209	arg1	management					217:226	slow or non-healing wound management	191:226	slow or non-healing wound management	191:226	Exudate management remains a major concern in slow or non-healing wound management.					
36243366	11	72	theme	chain	2053:2057	arg1	rearrangement					2059:2071	polymer chain rearrangement	2045:2071	polymer chain rearrangement	2045:2071	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	9	73	dep	STATEMENT	1621:1629	arg1	Hydrogels					1648:1656	Hydrogels	1648:1656	Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities	1648:1782	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	9	73	dep	STATEMENT	1621:1629	arg1	dressings					1794:1802	ideal dressings	1788:1802	ideal dressings for accelerating chronic wound contraction	1788:1845	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	3	74	theme	in	599:600	arg1	gelation					607:614	in situ gelation	599:614	in situ gelation	599:614	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	9	75	theme	ECM-like	1714:1721	arg1	network					1723:1729	stable ECM-like network	1707:1729	stable ECM-like network	1707:1729	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	7	76	theme	wounds	1381:1386	arg1	closure					1362:1368	the closure	1358:1368	the closure of chronic wounds	1358:1386	This study suggested that FHoC biomaterial could accelerate the closure of chronic wounds.					
36243366	8	77	theme	gelation	1440:1447	arg1	strategy					1449:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	this unique FHoCP(5)-based in situ gelation strategy	1405:1456	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	11	78	theme	physical	2086:2093	arg1	barrier					2095:2101	a physical barrier	2084:2101	a physical barrier for hemostasis and anti-bacterial invasion	2084:2144	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	12	79	theme	fibroblast	2333:2342	arg1	migration					2344:2352	hydrophobic Fc improved fibroblast migration	2309:2352	hydrophobic Fc improved fibroblast migration	2309:2352	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	12	80	theme	rigid	2247:2251	arg1	Fc					2253:2254	rigid Fc	2247:2254	rigid Fc	2247:2254	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	0	81	theme	copolymer	69:77	arg1	biomaterial					79:89	ferrocene-hyaluronic acid organic copolymer biomaterial	35:89	ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing	35:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	5	82	theme	physical	1046:1053	arg1	network					979:985	a firm three-dimensional network	954:985	a firm three-dimensional network	954:985	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	5	82	theme	physical	1046:1053	arg1	barrier					1055:1061	a physical barrier	1044:1061	a physical barrier against hemostasis and anti-bacterial invasion	1044:1108	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	9	83	theme	multimodal	1748:1757	arg1	healing					1765:1771	multimodal wound healing	1748:1771	multimodal wound healing activities	1748:1782	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	12	84	theme	backbone	2295:2302	arg1	core					2241:2244	the structural core	2226:2244	the structural core	2226:2244	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	12	84	theme	backbone	2295:2302	arg1	stability					2269:2277	the stability	2265:2277	the stability of the hydrogel backbone	2265:2302	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	9	85	theme	healing	1765:1771	arg1	activities					1773:1782	multimodal wound healing activities	1748:1782	multimodal wound healing activities	1748:1782	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	8	86	theme	drug-loaded	1480:1490	arg1	scaffold					1492:1499	a solid drug-loaded scaffold	1472:1499	a solid drug-loaded scaffold	1472:1499	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	4	87	theme	additional	741:750	arg1	microcrystalline					752:767	additional microcrystalline	741:767	additional microcrystalline	741:767	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	0	88	theme	multi-modal	118:128	arg1	healing					136:142	multi-modal wound healing	118:142	multi-modal wound healing	118:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	5	89	theme	firm	956:959	arg1	network					979:985	a firm three-dimensional network	954:985	a firm three-dimensional network	954:985	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	5	89	theme	firm	956:959	arg1	barrier					1055:1061	a physical barrier	1044:1061	a physical barrier against hemostasis and anti-bacterial invasion	1044:1108	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	8	90	theme	drug	1524:1527	arg1	therapies					1529:1537	cell or adjunctive drug therapies	1505:1537	therapies	1529:1537	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	10	91	theme	metal	1882:1886	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	91	theme	metal	1882:1886	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	4	92	theme	polymer	718:724	arg1	chains					726:731	polymer chains	718:731	polymer chains	718:731	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	5	93	theme	water	933:937	arg1	weight					923:928	its weight	919:928	150 times its weight of water	909:937	Thus, the simple composition FHoCP(5) absorbed 150 times its weight of water and maintained a firm three-dimensional network, which contributed to reducing inflammation and acted as a physical barrier against hemostasis and anti-bacterial invasion.					
36243366	14	94	from	potential	2459:2467	arg1	reconstruction					2526:2539	clinical skin reconstruction	2512:2539	clinical skin reconstruction	2512:2539	These results indicated the potential of FHoCP-based hydrogel for application in clinical skin reconstruction.					
36243366	9	95	theme	wound	1829:1833	arg1	contraction					1835:1845	chronic wound contraction	1821:1845	chronic wound contraction	1821:1845	STATEMENT OF SIGNIFICANCE: Hydrogels that absorb excessive exudates while maintaining stable ECM-like network as well as exert multimodal wound healing activities are ideal dressings for accelerating chronic wound contraction.					
36243366	10	96	dep	in	1965:1966	arg1	situ					1968:1971	situ	1968:1971	situ	1968:1971	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	4	97	theme	hydrophobic	773:783	arg1	regions					785:791	hydrophobic regions	773:791	hydrophobic regions	773:791	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	10	98	theme	innovative	1871:1880	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	98	theme	innovative	1871:1880	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	12	99	theme	structural	2230:2239	arg1	core					2241:2244	the structural core	2226:2244	the structural core	2226:2244	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	12	99	theme	structural	2230:2239	arg1	stability					2269:2277	the stability	2265:2277	the stability of the hydrogel backbone	2265:2302	As the structural core, rigid Fc enhanced the stability of the hydrogel backbone, and hydrophobic Fc improved fibroblast migration.					
36243366	3	100	theme	sandwich	456:463	arg1	Fc					476:477	Fc	476:477	Fc	476:477	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	100	theme	sandwich	456:463	arg1	ferrocene					465:473	sandwich ferrocene	456:473	sandwich ferrocene (Fc)	456:478	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	4	101	theme	hydrogel	809:816	arg1	transition					818:827	hydrogel transition	809:827	hydrogel transition	809:827	Fc promoted the rearrangement of polymer chains to form additional microcrystalline and hydrophobic regions, which improved hydrogel transition and the exudate-locking ability.					
36243366	14	102	theme	FHoCP-based	2472:2482	arg1	hydrogel					2484:2491	FHoCP-based hydrogel	2472:2491	FHoCP-based hydrogel	2472:2491	These results indicated the potential of FHoCP-based hydrogel for application in clinical skin reconstruction.					
36243366	3	103	theme	hyaluronic	485:494	arg1	HA					502:503	HA	502:503	HA	502:503	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	103	theme	hyaluronic	485:494	arg1	acid					496:499	hyaluronic acid	485:499	hyaluronic acid (HA)	485:504	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	0	104	theme	acid	56:59	arg1	biomaterial					79:89	ferrocene-hyaluronic acid organic copolymer biomaterial	35:89	ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing	35:142	In situ gelation strategy based on ferrocene-hyaluronic acid organic copolymer biomaterial for exudate management and multi-modal wound healing.					
36243366	8	105	dep	-based	1425:1430	arg1	in					1432:1433	in	1432:1433	in	1432:1433	We believe that this unique FHoCP(5)-based in situ gelation strategy could provide a solid drug-loaded scaffold for cell or adjunctive drug therapies, which holds great potential for the development of multifunctional biomaterials.					
36243366	11	106	theme	delayed	2201:2207	arg1	inflammation					2209:2220	delayed inflammation	2201:2220	delayed inflammation	2201:2220	Ferrocene (Fc) induced in situ gelation by promoting polymer chain rearrangement, acting as a physical barrier for hemostasis and anti-bacterial invasion, and absorbing massive exudates, resulting in reducing delayed inflammation.					
36243366	10	107	theme	organic	1914:1920	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	107	theme	organic	1914:1920	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	3	108	theme	innovative	522:531	arg1	material					586:593	the skeleton material	573:593	the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP)	573:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	108	theme	innovative	522:531	arg1	FHoC					564:567	FHoC	564:567	FHoC	564:567	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	108	theme	innovative	522:531	arg1	copolymer					553:561	an innovative metal Fc-HA organic copolymer	519:561	an innovative metal Fc-HA organic copolymer (FHoC)	519:568	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	6	109	theme	gelled	1243:1248	arg1	5					1256:1256	5	1256:1256	5	1256:1256	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	6	109	theme	gelled	1243:1248	arg1	FHoCP					1250:1254	the gelled FHoCP	1239:1254	the gelled FHoCP(5) guided by Fe to promote wound healing	1239:1295	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	10	110	theme	ferrocene-hyaluronic	1888:1907	arg1	FHoCP					1939:1943	FHoCP	1939:1943	FHoCP	1939:1943	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	10	110	theme	ferrocene-hyaluronic	1888:1907	arg1	patch					1932:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch	1868:1936	an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP)	1868:1944	Herein, we reported an innovative metal ferrocene-hyaluronic acid organic copolymer patch (FHoCP) and FHoCP-mediated in situ gelation strategy.					
36243366	2	111	theme	extracellular	323:335	arg1	matrix					337:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix	266:342	a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing	266:390	Therefore, there is a need to devise a massive exudate-absorbing, exudate-locking, and stable extracellular matrix structure-maintaining functional wound dressing.					
36243366	6	112	theme	Meanwhile	1111:1119	arg1	migration					1166:1174	fibroblast migration	1155:1174	fibroblast migration	1155:1174	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	6	112	theme	Meanwhile	1111:1119	arg1	effects					1209:1215	antibacterial effects	1195:1215	antibacterial effects	1195:1215	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	6	112	theme	Meanwhile	1111:1119	arg1	processes					1134:1142	Meanwhile, multi-modal processes	1111:1142	Meanwhile, multi-modal processes	1111:1142	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	6	112	theme	Meanwhile	1111:1119	arg1	angiogenesis					1177:1188	angiogenesis	1177:1188	angiogenesis	1177:1188	Meanwhile, multi-modal processes, including fibroblast migration, angiogenesis, and antibacterial effects, were integrated into the gelled FHoCP(5) guided by Fe to promote wound healing.					
36243366	3	113	theme	Fc-HA	539:543	arg1	material					586:593	the skeleton material	573:593	the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP)	573:682	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	113	theme	Fc-HA	539:543	arg1	FHoC					564:567	FHoC	564:567	FHoC	564:567	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36243366	3	113	theme	Fc-HA	539:543	arg1	copolymer					553:561	an innovative metal Fc-HA organic copolymer	519:561	an innovative metal Fc-HA organic copolymer (FHoC)	519:568	Inspired by metal-organic frameworks, we chemically introduced sandwich ferrocene (Fc) into hyaluronic acid (HA) to fabricate an innovative metal Fc-HA organic copolymer (FHoC) as the skeleton material for in situ gelation, which was then gently compressed into a pre-hydrogel patch (FHoCP).					
36779683	4	0	theme	water-soluble	902:914	arg1	Col					916:918	water-soluble Col	902:918	water-soluble Col (above 60% solution)	902:939	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	9	1	theme	synergistic	1824:1834	arg1	effects					1836:1842	The synergistic effects	1820:1842	The synergistic effects of Ns and Cs	1820:1855	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	5	2	contain	has	1180:1182	arg1	solution					1127:1134	50% solution	1123:1134	50% solution	1123:1134	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	2	contain	has	1180:1182	arg1	Col					1118:1120	water soluble Col	1104:1120	water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution)	1104:1178	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	2	contain	has	1180:1182	arg2	formation					1195:1203	good fiber formation	1184:1203	good fiber formation with mean diameter 384 ± 27 nm	1184:1234	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	7	3	from	biopolymers	1490:1500	arg1	bio-nanocomposite					1505:1521	bio-nanocomposite	1505:1521	bio-nanocomposite	1505:1521	All of the biopolymers in bio-nanocomposite improve the H-bonds, which accounts for enough tensile strength to withstand cell pulling force.					
36779683	1	4	theme	manufacturing	231:243	arg1	technology					245:254	advanced manufacturing technology	222:254	advanced manufacturing technology	222:254	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	2	5	theme	hybrid	381:386	arg1	bio-nanocomposites					388:405	hybrid bio-nanocomposites	381:405	hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs)	381:468	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	3	6	theme	cell	758:761	arg1	cytotoxicity					763:774	cell cytotoxicity	758:774	cell cytotoxicity	758:774	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	3	7	theme	Fiber	588:592	arg1	morphologies					594:605	Fiber morphologies	588:605	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites	588:857	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	6	8	theme	bio-polymers	1465:1476	arg1	effects					1454:1460	the synergistic effects	1438:1460	the synergistic effects of bio-polymers	1438:1476	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	7	9	theme	cell	1600:1603	arg1	force					1613:1617	cell pulling force	1600:1617	cell pulling force	1600:1617	All of the biopolymers in bio-nanocomposite improve the H-bonds, which accounts for enough tensile strength to withstand cell pulling force.					
36779683	3	10	theme	rabbit	802:807	arg1	model					809:813	rabbit model	802:813	rabbit model of the fabricated hybrid bio-nanocomposites	802:857	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	6	11	theme	gaseous	1381:1387	arg1	exchange					1389:1396	allowing gaseous exchange	1372:1396	allowing gaseous exchange	1372:1396	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	1	12	theme	bio-inscribed	278:290	arg1	materials					292:300	bio-inscribed materials	278:300	bio-inscribed materials	278:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	10	13	theme	hybrid	2084:2089	arg1	bio-composites					2091:2104	the fabricated hybrid bio-composites	2069:2104	the fabricated hybrid bio-composites	2069:2104	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	10	13	theme	hybrid	2084:2089	arg1	useful					2113:2118	useful	2113:2118	useful	2113:2118	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	3	14	theme	electron	624:631	arg1	microscope					633:642	scanning electron microscope	615:642	scanning electron microscope (SEM)	615:648	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	3	14	theme	electron	624:631	arg1	SEM					645:647	SEM	645:647	SEM	645:647	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	7	15	theme	tensile	1570:1576	arg1	strength					1578:1585	tensile strength	1570:1585	tensile strength	1570:1585	All of the biopolymers in bio-nanocomposite improve the H-bonds, which accounts for enough tensile strength to withstand cell pulling force.					
36779683	2	16	from	layer	536:540	arg1	ratio					557:561	a different ratio	545:561	a different ratio for tissue regeneration	545:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	9	17	theme	antibacterial	1912:1924	arg1	activity					1926:1933	antibacterial activity	1912:1933	antibacterial activity	1912:1933	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	3	18	theme	fabricated	822:831	arg1	bio-nanocomposites					840:857	the fabricated hybrid bio-nanocomposites	818:857	the fabricated hybrid bio-nanocomposites	818:857	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	9	19	dep	%	1982:1982	arg1	84					1980:1981	84	1980:1981	84	1980:1981	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	4	20	dep	%	929:929	arg1	solution					931:938	solution	931:938	above 60% solution	921:938	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	5	21	with	formation	1195:1203	arg1	diameter					1215:1222	mean diameter 384 ± 27 nm	1210:1234	mean diameter 384 ± 27 nm	1210:1234	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	22	theme	fiber	1189:1193	arg1	formation					1195:1203	good fiber formation	1184:1203	good fiber formation with mean diameter 384 ± 27 nm	1184:1234	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	23	theme	%	1125:1125	arg1	Col					1118:1120	water soluble Col	1104:1120	water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution)	1104:1178	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	23	theme	%	1125:1125	arg1	solution					1127:1134	50% solution	1123:1134	50% solution	1123:1134	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	8	24	theme	bacterial	1762:1770	arg1	action					1772:1777	bacterial action	1762:1777	bacterial action with 100% cell viability (cytotoxicity)	1762:1817	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	2	25	theme	different	547:555	arg1	ratio					557:561	a different ratio	545:561	a different ratio for tissue regeneration	545:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	3	26	theme	bio-nanocomposites	840:857	arg1	model					809:813	rabbit model	802:813	rabbit model of the fabricated hybrid bio-nanocomposites	802:857	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	6	27	theme	slow-drying	1290:1300	arg1	bio-nanocomposites					1309:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	8	28	dep	10	1692:1693	arg1	appeared					1725:1732	appeared	1725:1732	appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity)	1725:1817	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	6	29	theme	fast-absorbing	1271:1284	arg1	bio-nanocomposites					1309:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	5	30	theme	soluble	1110:1116	arg1	Col					1118:1120	water soluble Col	1104:1120	water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution)	1104:1178	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	30	theme	soluble	1110:1116	arg1	solution					1127:1134	50% solution	1123:1134	50% solution	1123:1134	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	2	31	theme	polyvinyl	511:519	arg1	PVA					531:533	PVA	531:533	PVA	531:533	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	31	theme	polyvinyl	511:519	arg1	chloride					521:528	polyvinyl chloride	511:528	polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration	511:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	8	32	theme	%	1787:1787	arg1	cytotoxicity					1805:1816	cytotoxicity	1805:1816	cytotoxicity	1805:1816	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	8	32	theme	%	1787:1787	arg1	viability					1794:1802	100% cell viability	1784:1802	100% cell viability (cytotoxicity)	1784:1817	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	4	33	theme	solution	1045:1052	arg1	tension					1030:1036	the surface tension	1018:1036	the surface tension of the solution (viscosity) to form fibers	1018:1079	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	0	34	theme	Collagen/Nigella	0:15	arg1	sativa/chitosan					17:31	Collagen/Nigella sativa/chitosan	0:31	Collagen/Nigella sativa/chitosan	0:31	Collagen/Nigella sativa/chitosan inscribed electrospun hybrid bio-nanocomposites for skin tissue engineering.					
36779683	1	35	theme	new	128:130	arg1	regeneration					139:150	The sophisticated new tissue regeneration	110:150	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials	110:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	6	36	theme	allowing	1372:1379	arg1	exchange					1389:1396	allowing gaseous exchange	1372:1396	allowing gaseous exchange	1372:1396	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	4	37	theme	surface	1022:1028	arg1	tension					1030:1036	the surface tension	1018:1036	the surface tension of the solution (viscosity) to form fibers	1018:1079	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	0	38	theme	tissue	90:95	arg1	engineering					97:107	skin tissue engineering	85:107	skin tissue engineering	85:107	Collagen/Nigella sativa/chitosan inscribed electrospun hybrid bio-nanocomposites for skin tissue engineering.					
36779683	9	39	theme	only	2001:2004	arg1	10 days					2006:2012	only 10 days	2001:2012	only 10 days	2001:2012	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	0	40	theme	hybrid	55:60	arg1	bio-nanocomposites					62:79	electrospun hybrid bio-nanocomposites	43:79	electrospun hybrid bio-nanocomposites for skin tissue engineering	43:107	Collagen/Nigella sativa/chitosan inscribed electrospun hybrid bio-nanocomposites for skin tissue engineering.					
36779683	4	41	dep	Col	916:918	arg1	%					929:929	above 60%	921:929	above 60% solution	921:938	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	3	42	theme	infrared	669:676	arg1	spectroscopy					678:689	infrared spectroscopy	669:689	infrared spectroscopy (FTIR)	669:696	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	3	42	theme	infrared	669:676	arg1	FTIR					692:695	FTIR	692:695	FTIR	692:695	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	9	43	from	closure	1990:1996	arg1	10 days					2006:2012	only 10 days	2001:2012	only 10 days	2001:2012	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	3	44	theme	moisture	699:706	arg1	management					708:717	moisture management	699:717	moisture management	699:717	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	6	45	theme	synergistic	1442:1452	arg1	effects					1454:1460	the synergistic effects	1438:1460	the synergistic effects of bio-polymers	1438:1476	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	5	46	theme	%	1168:1168	arg1	solution					1170:1177	25% solution	1166:1177	25% solution	1166:1177	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	46	theme	%	1168:1168	arg1	Ns					1162:1163	Ns	1162:1163	Ns (25% solution)	1162:1178	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	2	47	theme	sativa	436:441	arg1	oil					448:450	Nigella sativa (Ns) oil	428:450	Nigella sativa (Ns) oil	428:450	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	8	48	theme	antibacterial	1624:1636	arg1	10					1692:1693	10	1692:1693	10	1692:1693	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	8	48	theme	antibacterial	1624:1636	arg1	concentrations					1642:1655	The antibacterial ZOI concentrations	1620:1655	The antibacterial ZOI concentrations against S. aureus and E. coli	1620:1685	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	9	49	dep	closure	1990:1996	arg1	%					1982:1982	%	1982:1982	%	1982:1982	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	1	50	theme	research	317:324	arg1	interest					338:345	the research community's interest	313:345	the research community's interest	313:345	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	9	51	theme	control	2050:2056	arg1	model					2058:2062	the control model	2046:2062	the control model	2046:2062	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	6	52	theme	cell	1402:1405	arg1	migration					1407:1415	cell migration	1402:1415	cell migration	1402:1415	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	9	53	theme	Ns	1847:1848	arg1	effects					1836:1842	The synergistic effects	1820:1842	The synergistic effects of Ns and Cs	1820:1855	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	1	54	theme	advanced	222:229	arg1	technology					245:254	advanced manufacturing technology	222:254	advanced manufacturing technology	222:254	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	9	55	theme	Cs	1854:1855	arg1	effects					1836:1842	The synergistic effects	1820:1842	The synergistic effects of Ns and Cs	1820:1855	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	3	56	theme	antibacterial	734:746	arg1	activity					748:755	antibacterial activity	734:755	antibacterial activity	734:755	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	7	57	theme	pulling	1605:1611	arg1	force					1613:1617	cell pulling force	1600:1617	cell pulling force	1600:1617	All of the biopolymers in bio-nanocomposite improve the H-bonds, which accounts for enough tensile strength to withstand cell pulling force.					
36779683	9	58	theme	tissue	1865:1870	arg1	regeneration					1872:1883	tissue regeneration	1865:1883	tissue regeneration	1865:1883	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	3	59	theme	wound	780:784	arg1	healing					786:792	wound healing	780:792	wound healing	780:792	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	10	60	theme	skin	2124:2127	arg1	engineering					2136:2146	skin tissue engineering	2124:2146	skin tissue engineering	2124:2146	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	2	61	theme	tissue	567:572	arg1	regeneration					574:585	tissue regeneration	567:585	tissue regeneration	567:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	9	62	theme	native	1892:1897	arg1	Col					1899:1901	native Col	1892:1901	native Col	1892:1901	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	3	63	theme	scanning	615:622	arg1	microscope					633:642	scanning electron microscope	615:642	scanning electron microscope (SEM)	615:648	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	3	63	theme	scanning	615:622	arg1	SEM					645:647	SEM	645:647	SEM	645:647	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	10	64	theme	fabricated	2073:2082	arg1	bio-composites					2091:2104	the fabricated hybrid bio-composites	2069:2104	the fabricated hybrid bio-composites	2069:2104	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	10	64	theme	fabricated	2073:2082	arg1	useful					2113:2118	useful	2113:2118	useful	2113:2118	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	5	65	theme	mean	1210:1213	arg1	diameter					1215:1222	mean diameter 384 ± 27 nm	1210:1234	mean diameter 384 ± 27 nm	1210:1234	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	3	66	theme	hybrid	833:838	arg1	bio-nanocomposites					840:857	the fabricated hybrid bio-nanocomposites	818:857	the fabricated hybrid bio-nanocomposites	818:857	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	6	67	theme	moist	1339:1343	arg1	environment					1345:1355	a moist environment	1337:1355	a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation	1337:1433	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	1	68	theme	different	182:190	arg1	morphologies					192:203	different morphologies	182:203	different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials	182:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	1	69	theme	materials	292:300	arg1	inclusion					265:273	the inclusion	261:273	the inclusion of bio-inscribed materials	261:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	5	70	theme	good	1184:1187	arg1	formation					1195:1203	good fiber formation	1184:1203	good fiber formation with mean diameter 384 ± 27 nm	1184:1234	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	2	71	theme	chloride	521:528	arg1	layer					536:540	polyvinyl chloride (PVA) layer	511:540	polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration	511:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	9	72	theme	rabbit	1944:1949	arg1	model					1951:1955	the rabbit model	1940:1955	the rabbit model	1940:1955	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	6	73	theme	hybrid	1302:1307	arg1	bio-nanocomposites					1309:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites	1267:1326	The fast-absorbing and slow-drying hybrid bio-nanocomposites maintain a moist environment for wounds and allowing gaseous exchange for cell migration and proliferation by the synergistic effects of bio-polymers.					
36779683	2	74	with	bio-nanocomposites	388:405	arg1	chitosan					456:463	chitosan	456:463	chitosan (Cs)	456:468	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	74	with	bio-nanocomposites	388:405	arg1	oil					448:450	Nigella sativa (Ns) oil	428:450	Nigella sativa (Ns) oil	428:450	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	74	with	bio-nanocomposites	388:405	arg1	Col					422:424	Col	422:424	Col	422:424	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	74	with	bio-nanocomposites	388:405	arg1	collagen					412:419	collagen	412:419	collagen (Col)	412:425	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	74	with	bio-nanocomposites	388:405	arg1	Cs					466:467	Cs	466:467	Cs	466:467	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	4	75	theme	Taylor	955:960	arg1	cones					962:966	Taylor cones	955:966	Taylor cones	955:966	It is worth noting that water-soluble Col (above 60% solution) does not form Taylor cones during electrospinning because unable to overcome the surface tension of the solution (viscosity) to form fibers.					
36779683	2	76	from	electrospinning	492:506	arg1	layer					536:540	polyvinyl chloride (PVA) layer	511:540	polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration	511:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	10	77	theme	tissue	2129:2134	arg1	engineering					2136:2146	skin tissue engineering	2124:2146	skin tissue engineering	2124:2146	So, the fabricated hybrid bio-composites may be useful for skin tissue engineering.					
36779683	1	78	with	nanocomposite	163:175	arg1	morphologies					192:203	different morphologies	182:203	different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials	182:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	8	79	theme	100	1784:1786	arg1	%					1787:1787	%	1787:1787	%	1787:1787	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	1	80	theme	sophisticated	114:126	arg1	regeneration					139:150	The sophisticated new tissue regeneration	110:150	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials	110:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	9	81	theme	wound	1984:1988	arg1	closure					1990:1996	approximately 84% wound closure	1966:1996	approximately 84% wound closure	1966:1996	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	0	82	theme	electrospun	43:53	arg1	bio-nanocomposites					62:79	electrospun hybrid bio-nanocomposites	43:79	electrospun hybrid bio-nanocomposites for skin tissue engineering	43:107	Collagen/Nigella sativa/chitosan inscribed electrospun hybrid bio-nanocomposites for skin tissue engineering.					
36779683	5	83	theme	%	1146:1146	arg1	Cs					1140:1141	Cs	1140:1141	Cs (25% solution)	1140:1156	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	5	83	theme	%	1146:1146	arg1	solution					1148:1155	25% solution	1144:1155	25% solution	1144:1155	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	8	84	theme	cell	1789:1792	arg1	cytotoxicity					1805:1816	cytotoxicity	1805:1816	cytotoxicity	1805:1816	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	8	84	theme	cell	1789:1792	arg1	viability					1794:1802	100% cell viability	1784:1802	100% cell viability (cytotoxicity)	1784:1817	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	1	85	theme	tissue	132:137	arg1	regeneration					139:150	The sophisticated new tissue regeneration	110:150	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials	110:300	The sophisticated new tissue regeneration focused on nanocomposite with different morphologies achieved through advanced manufacturing technology with the inclusion of bio-inscribed materials has piqued the research community's interest.					
36779683	5	86	theme	porosity	1250:1257	arg1	degree					1240:1245	degree	1240:1245	degree of porosity	1240:1257	The results show that water soluble Col (50% solution) to Cs (25% solution) and Ns (25% solution) has good fiber formation with mean diameter 384 ± 27 nm and degree of porosity is 79%.					
36779683	0	87	theme	skin	85:88	arg1	engineering					97:107	skin tissue engineering	85:107	skin tissue engineering	85:107	Collagen/Nigella sativa/chitosan inscribed electrospun hybrid bio-nanocomposites for skin tissue engineering.					
36779683	2	88	theme	green	486:490	arg1	electrospinning					492:506	a bi-layered green electrospinning	473:506	a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration	473:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	9	89	theme	faster	2034:2039	arg1	times					2028:2032	1.5 times	2024:2032	1.5 times faster than the control model	2024:2062	The synergistic effects of Ns and Cs improve tissue regeneration, while native Col improves antibacterial activity, and the rabbit model achieves approximately 84% wound closure in only 10 days, which is 1.5 times faster than the control model.					
36779683	2	90	theme	Nigella	428:434	arg1	Ns					444:445	Ns	444:445	Ns	444:445	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	2	90	theme	Nigella	428:434	arg1	sativa					436:441	Nigella sativa	428:441	Nigella sativa (Ns) oil	428:450	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36779683	8	91	theme	ZOI	1638:1640	arg1	10					1692:1693	10	1692:1693	10	1692:1693	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	8	91	theme	ZOI	1638:1640	arg1	concentrations					1642:1655	The antibacterial ZOI concentrations	1620:1655	The antibacterial ZOI concentrations against S. aureus and E. coli	1620:1685	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	3	92	dep	Fourier	651:657	arg1	transform					659:667	transform	659:667	transform infrared spectroscopy (FTIR)	659:696	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	8	93	with	action	1772:1777	arg1	cytotoxicity					1805:1816	cytotoxicity	1805:1816	cytotoxicity	1805:1816	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	8	93	with	action	1772:1777	arg1	viability					1794:1802	100% cell viability	1784:1802	100% cell viability (cytotoxicity)	1784:1817	The antibacterial ZOI concentrations against S. aureus and E. coli were 10 and 8 mm, respectively, which appeared to be sufficient to inhibit bacterial action with 100% cell viability (cytotoxicity).					
36779683	3	94	theme	tensile	720:726	arg1	test					728:731	tensile test	720:731	tensile test	720:731	Fiber morphologies through scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), moisture management, tensile test, antibacterial activity, cell cytotoxicity and wound healing through rabbit model of the fabricated hybrid bio-nanocomposites were investigated.					
36779683	2	95	theme	bi-layered	475:484	arg1	electrospinning					492:506	a bi-layered green electrospinning	473:506	a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration	473:585	This research aims at developing hybrid bio-nanocomposites with collagen (Col), Nigella sativa (Ns) oil and chitosan (Cs) by a bi-layered green electrospinning on polyvinyl chloride (PVA) layer in a different ratio for tissue regeneration.					
36720197	5	0	theme	film	1111:1114	arg1	color					1116:1120	film color	1111:1120	film color	1111:1120	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	2	1	from	literature	405:414	arg1	present					390:396	present	390:396	present	390:396	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	1	2	theme	tunable	232:238	arg1	properties					263:272	tunable optical and mechanical properties	232:272	tunable optical and mechanical properties	232:272	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	0	3	theme	Nematic	79:85	arg1	Films					87:91	Iridescent Chiral Nematic Films	61:91	Iridescent Chiral Nematic Films	61:91	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	3	4	theme	different	579:587	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	7	5	theme	films	1422:1426	arg1	coassembly					1368:1377	coassembly	1368:1377	coassembly	1368:1377	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	7	5	theme	films	1422:1426	arg1	formation					1383:1391	formation	1383:1391	formation	1383:1391	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	2	6	attach	present	390:396	arg1	literature					405:414	the literature	401:414	the literature	401:414	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	2	6	attach	present	390:396	arg2	results					378:384	conflicting results	366:384	conflicting results	366:384	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	1	7	theme	optical	240:246	arg1	properties					263:272	tunable optical and mechanical properties	232:272	tunable optical and mechanical properties	232:272	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	6	8	theme	rheological	1246:1256	arg1	properties					1275:1284	interesting rheological and liquid-state properties	1234:1284	interesting rheological and liquid-state properties	1234:1284	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	0	9	from	Coassembly	0:9	arg1	Films					87:91	Iridescent Chiral Nematic Films	61:91	Iridescent Chiral Nematic Films	61:91	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	6	10	theme	hydroxyl	1158:1165	arg1	CNCs					1177:1180	CNCs	1177:1180	CNCs	1177:1180	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	6	10	theme	hydroxyl	1158:1165	arg1	groups					1167:1172	the hydroxyl groups	1154:1172	the hydroxyl groups of CNCs	1154:1180	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	5	11	theme	nematic	1062:1068	arg1	domains					1074:1080	chiral nematic CNC domains	1055:1080	chiral nematic CNC domains	1055:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	6	12	theme	interesting	1234:1244	arg1	properties					1275:1284	interesting rheological and liquid-state properties	1234:1284	interesting rheological and liquid-state properties	1234:1284	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	7	13	theme	greater	1442:1448	arg1	control					1450:1456	greater control	1442:1456	greater control over optical properties of future CNC-based materials	1442:1510	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	4	14	from	shift	881:885	arg1	color					895:899	film color	890:899	film color	890:899	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	7	15	theme	CNC-polymer	1336:1346	arg1	interactions					1348:1359	CNC-polymer interactions	1336:1359	CNC-polymer interactions	1336:1359	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	1	16	theme	mechanical	252:261	arg1	properties					263:272	tunable optical and mechanical properties	232:272	tunable optical and mechanical properties	232:272	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	4	17	theme	bathochromic	868:879	arg1	shift					881:885	a bathochromic shift	866:885	a bathochromic shift in film color with both increasing concentration and polymer molecular weight	866:963	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	3	18	theme	various	631:637	arg1	concentrations					639:652	various concentrations	631:652	various concentrations prior to obtaining iridescent composite thin films by solvent evaporation	631:726	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	7	19	theme	deeper	1312:1317	arg1	understanding					1319:1331	a deeper understanding	1310:1331	a deeper understanding of CNC-polymer interactions	1310:1359	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	6	20	theme	PAA	1132:1134	arg1	hydrogen					1136:1143	PAA hydrogen	1132:1143	PAA hydrogen	1132:1143	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	4	21	theme	increasing	911:920	arg1	concentration					922:934	increasing concentration	911:934	increasing concentration	911:934	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	3	22	theme	CNC	612:614	arg1	suspensions					616:626	CNC suspensions	612:626	CNC suspensions	612:626	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	5	23	theme	negligible	1090:1099	arg1	change					1101:1106	a negligible change	1088:1106	a negligible change in film color	1088:1120	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	2	24	theme	conflicting	366:376	arg1	results					378:384	conflicting results	366:384	conflicting results	366:384	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	4	25	theme	polymer	940:946	arg1	weight					958:963	polymer molecular weight	940:963	polymer molecular weight	940:963	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	4	26	theme	film	890:893	arg1	color					895:899	film color	890:899	film color	890:899	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	2	27	theme	polymers	301:308	arg1	influence					288:296	the influence	284:296	the influence of polymers on CNC self-assembly	284:329	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	1	28	theme	polymers	175:182	arg1	films					132:136	composite films	122:136	composite films of cellulose nanocrystals (CNCs) and polymers	122:182	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	6	29	theme	bathochromic	1198:1209	arg1	shift					1217:1221	a bathochromic color shift	1196:1221	a bathochromic color shift	1196:1221	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	5	30	theme	domains	1074:1080	arg1	size					1047:1050	the size	1043:1050	the size of chiral nematic CNC domains	1043:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	4	31	theme	rheological	772:782	arg1	analyses					784:791	spectroscopic, potentiometric, and rheological analyses	737:791	spectroscopic, potentiometric, and rheological analyses	737:791	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	7	32	theme	chiral	1407:1412	arg1	films					1422:1426	iridescent chiral nematic films	1396:1426	iridescent chiral nematic films	1396:1426	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	1	33	theme	Photonic	94:101	arg1	materials					103:111	Photonic materials	94:111	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers	94:182	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	0	34	theme	Nanocrystals	24:35	arg1	Coassembly					0:9	Coassembly	0:9	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.	0:92	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	6	35	theme	liquid-state	1262:1273	arg1	properties					1275:1284	interesting rheological and liquid-state properties	1234:1284	interesting rheological and liquid-state properties	1234:1284	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	0	36	theme	Cellulose	14:22	arg1	Nanocrystals					24:35	Cellulose Nanocrystals	14:35	Cellulose Nanocrystals	14:35	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	7	37	theme	future	1485:1490	arg1	materials					1502:1510	future CNC-based materials	1485:1510	future CNC-based materials	1485:1510	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	6	38	theme	color	1211:1215	arg1	shift					1217:1221	a bathochromic color shift	1196:1221	a bathochromic color shift	1196:1221	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	3	39	theme	acid	562:565	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	40	theme	water-soluble	462:474	arg1	PEG					508:510	PEG	508:510	PEG	508:510	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	40	theme	water-soluble	462:474	arg1	polymers-poly					476:488	three neutral, water-soluble polymers-poly	447:488	polymers-poly	476:488	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	40	theme	water-soluble	462:474	arg1	glycol					499:504	ethylene glycol	490:504	ethylene glycol	490:504	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	41	theme	ethylene	490:497	arg1	polymers-poly					476:488	three neutral, water-soluble polymers-poly	447:488	polymers-poly	476:488	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	41	theme	ethylene	490:497	arg1	glycol					499:504	ethylene glycol	490:504	ethylene glycol	490:504	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	0	42	theme	Neutral	41:47	arg1	Polymers					49:56	Neutral Polymers	41:56	Neutral Polymers	41:56	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	3	43	theme	prior	654:658	arg1	concentrations					639:652	various concentrations	631:652	various concentrations prior to obtaining iridescent composite thin films by solvent evaporation	631:726	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	4	44	theme	CNCs	848:851	arg1	surface					837:843	the surface	833:843	the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight	833:963	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	4	45	theme	spectroscopic	737:749	arg1	analyses					784:791	spectroscopic, potentiometric, and rheological analyses	737:791	spectroscopic, potentiometric, and rheological analyses	737:791	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	3	46	theme	vinyl	519:523	arg1	poly					514:517	poly	514:517	poly(vinyl pyrrolidone) (PVP)	514:542	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	46	theme	vinyl	519:523	arg1	pyrrolidone					525:535	vinyl pyrrolidone	519:535	vinyl pyrrolidone	519:535	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	47	theme	thin	694:697	arg1	films					699:703	iridescent composite thin films	673:703	iridescent composite thin films	673:703	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	5	48	from	change	1101:1106	arg1	color					1116:1120	film color	1111:1120	film color	1111:1120	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	5	49	theme	depletion	991:999	arg1	interactions					1001:1012	depletion interactions	991:1012	depletion interactions that result in a decrease in the size of chiral nematic CNC domains	991:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	5	50	theme	CNC	1070:1072	arg1	domains					1074:1080	chiral nematic CNC domains	1055:1080	chiral nematic CNC domains	1055:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	5	51	from	decrease	1031:1038	arg1	size					1047:1050	the size	1043:1050	the size of chiral nematic CNC domains	1043:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	5	52	theme	chiral	1055:1060	arg1	domains					1074:1080	chiral nematic CNC domains	1055:1080	chiral nematic CNC domains	1055:1080	In contrast, PEG induces depletion interactions that result in a decrease in the size of chiral nematic CNC domains, with a negligible change in film color.					
36720197	2	53	located	present	390:396	arg1	literature					405:414	the literature	401:414	the literature	401:414	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	2	53	located	present	390:396	arg2	results					378:384	conflicting results	366:384	conflicting results	366:384	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	4	54	theme	potentiometric	752:765	arg1	analyses					784:791	spectroscopic, potentiometric, and rheological analyses	737:791	spectroscopic, potentiometric, and rheological analyses	737:791	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	7	55	theme	interactions	1348:1359	arg1	understanding					1319:1331	a deeper understanding	1310:1331	a deeper understanding of CNC-polymer interactions	1310:1359	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	7	56	theme	optical	1463:1469	arg1	properties					1471:1480	optical properties	1463:1480	optical properties of future CNC-based materials	1463:1510	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	0	57	theme	Polymers	49:56	arg1	Coassembly					0:9	Coassembly	0:9	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.	0:92	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	3	58	theme	iridescent	673:682	arg1	films					699:703	iridescent composite thin films	673:703	iridescent composite thin films	673:703	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	59	theme	acrylic	554:560	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	1	60	theme	composite	122:130	arg1	films					132:136	composite films	122:136	composite films of cellulose nanocrystals (CNCs) and polymers	122:182	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	3	61	theme	composite	684:692	arg1	films					699:703	iridescent composite thin films	673:703	iridescent composite thin films	673:703	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	62	theme	-with	573:577	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	4	63	with	shift	881:885	arg1	concentration					922:934	increasing concentration	911:934	increasing concentration	911:934	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	4	63	with	shift	881:885	arg1	weight					958:963	polymer molecular weight	940:963	polymer molecular weight	940:963	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	2	64	theme	CNC	313:315	arg1	self-assembly					317:329	CNC self-assembly	313:329	CNC self-assembly	313:329	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	6	65	theme	CNCs	1177:1180	arg1	CNCs					1177:1180	CNCs	1177:1180	CNCs	1177:1180	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	6	65	theme	CNCs	1177:1180	arg1	groups					1167:1172	the hydroxyl groups	1154:1172	the hydroxyl groups of CNCs	1154:1180	Finally, PAA hydrogen bonds to the hydroxyl groups of CNCs, resulting in a bathochromic color shift along with interesting rheological and liquid-state properties.					
36720197	7	66	theme	nematic	1414:1420	arg1	films					1422:1426	iridescent chiral nematic films	1396:1426	iridescent chiral nematic films	1396:1426	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	3	67	theme	poly	549:552	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	2	68	from	present	390:396	arg1	literature					405:414	the literature	401:414	the literature	401:414	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	3	69	theme	neutral	453:459	arg1	PEG					508:510	PEG	508:510	PEG	508:510	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	69	theme	neutral	453:459	arg1	polymers-poly					476:488	three neutral, water-soluble polymers-poly	447:488	polymers-poly	476:488	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	69	theme	neutral	453:459	arg1	glycol					499:504	ethylene glycol	490:504	ethylene glycol	490:504	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	0	70	theme	Chiral	72:77	arg1	Films					87:91	Iridescent Chiral Nematic Films	61:91	Iridescent Chiral Nematic Films	61:91	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	3	71	theme	PAA	569:571	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	3	72	theme	molecular	589:597	arg1	weights					599:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	poly(acrylic acid) (PAA)-with different molecular weights	549:605	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
36720197	7	73	theme	materials	1502:1510	arg1	properties					1471:1480	optical properties	1463:1480	optical properties of future CNC-based materials	1463:1510	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	1	74	theme	cellulose	141:149	arg1	nanocrystals					151:162	cellulose nanocrystals	141:162	cellulose nanocrystals (CNCs)	141:169	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	1	74	theme	cellulose	141:149	arg1	CNCs					165:168	CNCs	165:168	CNCs	165:168	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	7	75	theme	CNC-based	1492:1500	arg1	materials					1502:1510	future CNC-based materials	1485:1510	future CNC-based materials	1485:1510	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	0	76	theme	Iridescent	61:70	arg1	Films					87:91	Iridescent Chiral Nematic Films	61:91	Iridescent Chiral Nematic Films	61:91	Coassembly of Cellulose Nanocrystals and Neutral Polymers in Iridescent Chiral Nematic Films.					
36720197	7	77	theme	iridescent	1396:1405	arg1	films					1422:1426	iridescent chiral nematic films	1396:1426	iridescent chiral nematic films	1396:1426	This work demonstrates a deeper understanding of CNC-polymer interactions during coassembly and formation of iridescent chiral nematic films, allowing for greater control over optical properties of future CNC-based materials.					
36720197	4	78	theme	molecular	948:956	arg1	weight					958:963	polymer molecular weight	940:963	polymer molecular weight	940:963	Through spectroscopic, potentiometric, and rheological analyses, we find that PVP physically adsorbs to the surface of CNCs resulting in a bathochromic shift in film color with both increasing concentration and polymer molecular weight.					
36720197	1	79	theme	nanocrystals	151:162	arg1	films					132:136	composite films	122:136	composite films of cellulose nanocrystals (CNCs) and polymers	122:182	Photonic materials based on composite films of cellulose nanocrystals (CNCs) and polymers are promising as they can be renewable and show tunable optical and mechanical properties.					
36720197	2	80	from	influence	288:296	arg1	self-assembly					317:329	CNC self-assembly	313:329	CNC self-assembly	313:329	However, the influence of polymers on CNC self-assembly is not always well understood, and conflicting results are present in the literature.					
36720197	3	81	theme	solvent	708:714	arg1	evaporation					716:726	solvent evaporation	708:726	solvent evaporation	708:726	In this study, we incorporate three neutral, water-soluble polymers-poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), and poly(acrylic acid) (PAA)-with different molecular weights into CNC suspensions at various concentrations prior to obtaining iridescent composite thin films by solvent evaporation.					
35467193	9	0	theme	river	1671:1675	arg1	water					1677:1681	river water	1671:1681	river water	1671:1681	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	7	1	theme	enthalpy	1400:1407	arg1	ΔHads					1417:1421	ΔHads	1417:1421	ΔHads	1417:1421	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	7	1	theme	enthalpy	1400:1407	arg1	change					1409:1414	the adsorption enthalpy change	1385:1414	the adsorption enthalpy change (ΔHads) of - 45 kJ/mol	1385:1437	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	4	2	theme	particles	812:820	arg1	addition					797:804	the addition	793:804	the addition of BG particles	793:820	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	7	3	dep	bonds	1326:1330	arg1	ii					1320:1321	ii	1320:1321	ii	1320:1321	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	8	4	theme	4.07 mg/g	1579:1587	arg1	values					1555:1560	adsorptive capacity (q0) values	1530:1560	adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively	1530:1601	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	4	5	theme	BG	809:810	arg1	particles					812:820	BG particles	809:820	BG particles	809:820	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	9	6	theme	humic	1728:1732	arg1	substances					1734:1743	humic substances	1728:1743	humic substances dissolved in natural water	1728:1770	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	1	7	theme	sugarcane	193:201	arg1	BG					212:213	BG	212:213	BG	212:213	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	7	theme	sugarcane	193:201	arg1	bagasse					203:209	sugarcane bagasse	193:209	sugarcane bagasse (BG)	193:214	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	5	8	theme	Freundlich	918:927	arg1	models					929:934	the Langmuir and Freundlich models	901:934	models	929:934	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	6	9	theme	dimensional	1115:1125	arg1	stability					1127:1135	dimensional stability	1115:1135	dimensional stability	1115:1135	Nevertheless, the addition of BG particles rendered outstanding mechanical reinforcement and dimensional stability to the adsorbents.					
35467193	7	10	theme	EE2	1349:1351	arg1	groups					1362:1367	HPMC and EE2 hydroxyl groups	1340:1367	groups	1362:1367	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	7	11	theme	H	1324:1324	arg1	bonds					1326:1330	(ii) H bonds	1319:1330	(ii) H bonds between HPMC and EE2 hydroxyl groups	1319:1367	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	8	12	from	solution	1490:1497	arg1	EE2					1473:1475	EE2	1473:1475	EE2 from aqueous solution	1473:1497	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	8	12	from	solution	1490:1497	arg1	experiments					1458:1468	Column adsorption experiments	1440:1468	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG	1440:1518	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	1	13	theme	fixed-bed	369:377	arg1	columns					379:385	fixed-bed columns	369:385	fixed-bed columns	369:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	5	14	theme	Langmuir	905:912	arg1	models					929:934	the Langmuir and Freundlich models	901:934	models	929:934	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	8	15	from	experiments	1458:1468	arg1	solution					1490:1497	aqueous solution	1482:1497	aqueous solution	1482:1497	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	8	15	from	experiments	1458:1468	arg1	HPMC50BG					1511:1518	HPMC50BG	1511:1518	HPMC50BG	1511:1518	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	8	15	from	experiments	1458:1468	arg1	HPMC					1502:1505	HPMC	1502:1505	HPMC	1502:1505	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	4	16	theme	surface	694:700	arg1	area					702:705	The porosity (~ 97%), specific surface area	663:705	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g)	663:724	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	4	16	theme	surface	694:700	arg1	m2/g					720:723	1.16 ± 0.10 m2/g	708:723	1.16 ± 0.10 m2/g	708:723	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	7	17	theme	EE2	1222:1224	arg1	methylene					1226:1234	EE2 methylene and aromatic groups	1222:1254	methylene	1226:1234	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	9	18	with	competition	1704:1714	arg1	substances					1734:1743	humic substances	1728:1743	humic substances dissolved in natural water	1728:1770	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	7	19	theme	hydrophobic	1189:1199	arg1	interactions					1201:1212	hydrophobic interactions	1189:1212	(i) hydrophobic interactions between EE2 methylene and aromatic groups	1185:1254	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	7	20	theme	HPMC	1260:1263	arg1	groups					1272:1277	HPMC methyl groups	1260:1277	HPMC methyl groups	1260:1277	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	3	21	theme	pure	565:568	arg1	208 ± 20 kPa					551:562	208 ± 20 kPa	551:562	208 ± 20 kPa (pure HPMC)	551:574	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	3	21	theme	pure	565:568	arg1	HPMC					570:573	pure HPMC	565:573	pure HPMC	565:573	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	1	22	theme	bagasse	203:209	arg1	microparticles					216:229	hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles	152:229	hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles	152:229	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	8	23	theme	adsorption	1447:1456	arg1	experiments					1458:1468	Column adsorption experiments	1440:1468	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG	1440:1518	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	6	24	theme	BG	1052:1053	arg1	particles					1055:1063	BG particles	1052:1063	BG particles	1052:1063	Nevertheless, the addition of BG particles rendered outstanding mechanical reinforcement and dimensional stability to the adsorbents.					
35467193	0	25	theme	Hydroxypropyl	0:12	arg1	bagasse					40:46	Hydroxypropyl methylcellulose-sugarcane bagasse	0:46	Hydroxypropyl methylcellulose-sugarcane bagasse	0:46	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	2	26	theme	BG	404:405	arg1	microparticles					407:420	BG microparticles	404:420	BG microparticles	404:420	HPMC chains and BG microparticles were crosslinked by the esterification with citric acid.					
35467193	0	27	theme	methylcellulose-sugarcane	14:38	arg1	bagasse					40:46	Hydroxypropyl methylcellulose-sugarcane bagasse	0:46	Hydroxypropyl methylcellulose-sugarcane bagasse	0:46	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	8	28	theme	Column	1440:1445	arg1	experiments					1458:1468	Column adsorption experiments	1440:1468	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG	1440:1518	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	7	29	theme	aromatic	1240:1247	arg1	groups					1249:1254	EE2 methylene and aromatic groups	1222:1254	groups	1249:1254	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	9	30	theme	EE2	1662:1664	arg1	adsorption					1648:1657	the adsorption	1644:1657	the adsorption of EE2 from river water	1644:1681	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	10	31	dep	83	1827:1828	arg1	to					1824:1825	to	1824:1825	to	1824:1825	The HPMC adsorbents could be recycled retaining up to 83% of the original efficiency.					
35467193	7	32	theme	methyl	1265:1270	arg1	groups					1272:1277	HPMC methyl groups	1260:1277	HPMC methyl groups	1260:1277	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	2	33	theme	citric	466:471	arg1	acid					473:476	citric acid	466:476	citric acid	466:476	HPMC chains and BG microparticles were crosslinked by the esterification with citric acid.					
35467193	1	34	theme	aqueous	298:304	arg1	solution					306:313	aqueous solution	298:313	aqueous solution in batch	298:322	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	35	from	solution	306:313	arg1	batch					318:322	batch	318:322	batch	318:322	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	35	from	solution	306:313	arg1	separation					252:261	the separation	248:261	the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns	248:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	4	36	theme	area	702:705	arg1	values					765:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values	663:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values	663:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	5	37	theme	composite	1002:1010	arg1	HPMC50BG					1012:1019	composite HPMC50BG	1002:1019	composite HPMC50BG	1002:1019	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	10	38	theme	efficiency	1847:1856	arg1	efficiency					1847:1856	the original efficiency	1834:1856	the original efficiency	1834:1856	The HPMC adsorbents could be recycled retaining up to 83% of the original efficiency.					
35467193	10	38	theme	efficiency	1847:1856	arg1	%					1829:1829	up to 83%	1821:1829	up to 83% of the original efficiency	1821:1856	The HPMC adsorbents could be recycled retaining up to 83% of the original efficiency.					
35467193	6	39	theme	mechanical	1086:1095	arg1	reinforcement					1097:1109	outstanding mechanical reinforcement	1074:1109	outstanding mechanical reinforcement	1074:1109	Nevertheless, the addition of BG particles rendered outstanding mechanical reinforcement and dimensional stability to the adsorbents.					
35467193	7	40	dep	interactions	1201:1212	arg1	i					1186:1186	i	1186:1186	i	1186:1186	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	9	41	theme	EE2	1719:1721	arg1	competition					1704:1714	the competition	1700:1714	the competition of EE2 with humic substances dissolved in natural water	1700:1770	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	10	42	theme	original	1838:1845	arg1	efficiency					1847:1856	the original efficiency	1834:1856	the original efficiency	1834:1856	The HPMC adsorbents could be recycled retaining up to 83% of the original efficiency.					
35467193	4	43	theme	degree	739:744	arg1	values					765:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values	663:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values	663:770	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	6	44	theme	outstanding	1074:1084	arg1	reinforcement					1097:1109	outstanding mechanical reinforcement	1074:1109	outstanding mechanical reinforcement	1074:1109	Nevertheless, the addition of BG particles rendered outstanding mechanical reinforcement and dimensional stability to the adsorbents.					
35467193	5	45	theme	adsorption	827:836	arg1	isotherms					838:846	The adsorption isotherms	823:846	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG	823:889	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	1	46	from	freshwater	355:364	arg1	columns					379:385	fixed-bed columns	369:385	fixed-bed columns	369:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	46	from	freshwater	355:364	arg1	separation					252:261	the separation	248:261	the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns	248:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	6	47	theme	particles	1055:1063	arg1	addition					1040:1047	the addition	1036:1047	the addition of BG particles	1036:1063	Nevertheless, the addition of BG particles rendered outstanding mechanical reinforcement and dimensional stability to the adsorbents.					
35467193	0	48	from	solution	108:115	arg1	removal					63:69	removal	63:69	removal of 17α-ethinylestradiol from aqueous solution and freshwater	63:130	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	3	49	theme	BG	613:614	arg1	particles					616:624	BG particles	613:624	BG particles added to HPMC	613:638	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	7	50	theme	hydroxyl	1353:1360	arg1	groups					1362:1367	HPMC and EE2 hydroxyl groups	1340:1367	groups	1362:1367	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	4	51	dep	porosity	667:674	arg1	%					681:681	~ 97%	677:681	~ 97%	677:681	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	4	51	dep	porosity	667:674	arg1	specific					685:692	specific	685:692	specific	685:692	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	8	52	theme	capacity	1541:1548	arg1	values					1555:1560	adsorptive capacity (q0) values	1530:1560	adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively	1530:1601	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	3	53	theme	particles	616:624	arg1	%					649:649	50 wt%	644:649	50 wt% (HPMC50BG)	644:660	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	3	53	theme	particles	616:624	arg1	content					602:608	the content	598:608	the content of BG particles added to HPMC	598:638	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	0	54	theme	17α-ethinylestradiol	74:93	arg1	removal					63:69	removal	63:69	removal of 17α-ethinylestradiol from aqueous solution and freshwater	63:130	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	8	55	theme	aqueous	1482:1488	arg1	solution					1490:1497	aqueous solution	1482:1497	aqueous solution	1482:1497	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	3	56	theme	wt	647:648	arg1	%					649:649	50 wt%	644:649	50 wt% (HPMC50BG)	644:660	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	3	56	theme	wt	647:648	arg1	content					602:608	the content	598:608	the content of BG particles added to HPMC	598:638	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	3	56	theme	wt	647:648	arg1	HPMC50BG					652:659	HPMC50BG	652:659	HPMC50BG	652:659	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	5	57	theme	HPMC	964:967	arg1	higher					982:987	higher	982:987	higher	982:987	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	5	57	theme	HPMC	964:967	arg1	capacity					952:959	the adsorption capacity	937:959	the adsorption capacity of HPMC	937:967	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	2	58	with	esterification	446:459	arg1	acid					473:476	citric acid	466:476	citric acid	466:476	HPMC chains and BG microparticles were crosslinked by the esterification with citric acid.					
35467193	10	59	theme	HPMC	1777:1780	arg1	adsorbents					1782:1791	The HPMC adsorbents	1773:1791	The HPMC adsorbents	1773:1791	The HPMC adsorbents could be recycled retaining up to 83% of the original efficiency.					
35467193	8	60	theme	EE2	1473:1475	arg1	experiments					1458:1468	Column adsorption experiments	1440:1468	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG	1440:1518	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	1	61	theme	hydroxypropyl	152:164	arg1	methylcellulose					166:180	hydroxypropyl methylcellulose	152:180	hydroxypropyl methylcellulose (HPMC)	152:187	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	61	theme	hydroxypropyl	152:164	arg1	HPMC					183:186	HPMC	183:186	HPMC	183:186	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	62	theme	aqueous	334:340	arg1	solution					342:349	aqueous solution	334:349	aqueous solution	334:349	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	9	63	from	water	1677:1681	arg1	adsorption					1648:1657	the adsorption	1644:1657	the adsorption of EE2 from river water	1644:1681	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	7	64	theme	FTIR	1296:1299	arg1	spectroscopy					1301:1312	FTIR spectroscopy	1296:1312	FTIR spectroscopy	1296:1312	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	7	65	theme	HPMC	1340:1343	arg1	groups					1362:1367	HPMC and EE2 hydroxyl groups	1340:1367	groups	1362:1367	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	1	66	theme	methylcellulose	166:180	arg1	microparticles					216:229	hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles	152:229	hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles	152:229	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	9	67	theme	natural	1758:1764	arg1	water					1766:1770	natural water	1758:1770	natural water	1758:1770	These values decreased considerably for the adsorption of EE2 from river water, probably due to the competition of EE2 with humic substances dissolved in natural water.					
35467193	4	68	theme	swelling	730:737	arg1	water/g					756:762	20 ± 1 g water/g	747:762	20 ± 1 g water/g	747:762	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	4	68	theme	swelling	730:737	arg1	degree					739:744	swelling degree	730:744	swelling degree (20 ± 1 g water/g)	730:763	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	7	69	theme	change	1409:1414	arg1	of - 45 kJ/mol					1424:1437	the adsorption enthalpy change (ΔHads) of - 45 kJ/mol	1385:1437	the adsorption enthalpy change (ΔHads) of - 45 kJ/mol	1385:1437	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	3	70	theme	modulus	516:522	arg1	values					524:529	compression modulus values	504:529	compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG)	504:660	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	3	71	theme	compression	504:514	arg1	values					524:529	compression modulus values	504:529	compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG)	504:660	The adsorbents presented compression modulus values that increased from 208 ± 20 kPa (pure HPMC) to 917 ± 90 kPa, when the content of BG particles added to HPMC was 50 wt% (HPMC50BG).					
35467193	0	72	theme	aqueous	100:106	arg1	solution					108:115	aqueous solution	100:115	aqueous solution	100:115	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	0	73	from	freshwater	121:130	arg1	removal					63:69	removal	63:69	removal of 17α-ethinylestradiol from aqueous solution and freshwater	63:130	Hydroxypropyl methylcellulose-sugarcane bagasse adsorbents for removal of 17α-ethinylestradiol from aqueous solution and freshwater.					
35467193	2	74	theme	HPMC	388:391	arg1	chains					393:398	HPMC chains	388:398	HPMC chains	388:398	HPMC chains and BG microparticles were crosslinked by the esterification with citric acid.					
35467193	8	75	theme	8.06 mg/g	1565:1573	arg1	values					1555:1560	adsorptive capacity (q0) values	1530:1560	adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively	1530:1601	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	8	76	theme	adsorptive	1530:1539	arg1	q0					1551:1552	q0	1551:1552	q0	1551:1552	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	8	76	theme	adsorptive	1530:1539	arg1	capacity					1541:1548	adsorptive capacity	1530:1548	adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively	1530:1601	Column adsorption experiments of EE2 from aqueous solution on HPMC and HPMC50BG indicated adsorptive capacity (q0) values of 8.06 mg/g and 4.07 mg/g, respectively.					
35467193	1	77	from	solution	342:349	arg1	columns					379:385	fixed-bed columns	369:385	fixed-bed columns	369:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	1	77	from	solution	342:349	arg1	separation					252:261	the separation	248:261	the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns	248:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
35467193	7	78	theme	adsorption	1389:1398	arg1	ΔHads					1417:1421	ΔHads	1417:1421	ΔHads	1417:1421	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	7	78	theme	adsorption	1389:1398	arg1	change					1409:1414	the adsorption enthalpy change	1385:1414	the adsorption enthalpy change (ΔHads) of - 45 kJ/mol	1385:1437	The adsorption was driven by (i) hydrophobic interactions between EE2 methylene and aromatic groups and HPMC methyl groups, as evidenced by FTIR spectroscopy, and (ii) H bonds between HPMC and EE2 hydroxyl groups, as revealed by the adsorption enthalpy change (ΔHads) of - 45 kJ/mol.					
35467193	5	79	theme	adsorption	941:950	arg1	higher					982:987	higher	982:987	higher	982:987	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	5	79	theme	adsorption	941:950	arg1	capacity					952:959	the adsorption capacity	937:959	the adsorption capacity of HPMC	937:967	The adsorption isotherms determined for EE2 on HPMC and on HPMC50BG fitted to the Langmuir and Freundlich models; the adsorption capacity of HPMC was slightly higher than that of composite HPMC50BG.					
35467193	4	80	theme	porosity	667:674	arg1	area					702:705	The porosity (~ 97%), specific surface area	663:705	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g)	663:724	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	4	80	theme	porosity	667:674	arg1	m2/g					720:723	1.16 ± 0.10 m2/g	708:723	1.16 ± 0.10 m2/g	708:723	The porosity (~ 97%), specific surface area (1.16 ± 0.10 m2/g) and swelling degree (20 ± 1 g water/g) values were not affected by the addition of BG particles.					
35467193	1	81	theme	17α-ethinylestradiol	266:285	arg1	separation					252:261	the separation	248:261	the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns	248:385	Adsorbents made of hydroxypropyl methylcellulose (HPMC) and sugarcane bagasse (BG) microparticles were applied for the separation of 17α-ethinylestradiol (EE2) from aqueous solution in batch, and from aqueous solution and freshwater in fixed-bed columns.					
36565172	0	0	theme	bone	91:94	arg1	protein-2					110:118	bone morphogenetic protein-2	91:118	bone morphogenetic protein-2	91:118	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	1	1	theme	healing	343:349	arg1	stage					329:333	each stage	324:333	each stage of bone healing	324:349	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	3	2	theme	bone	893:896	arg1	stages					905:910	early bone repair stages	887:910	early bone repair stages	887:910	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	3	3	theme	sustained	1001:1009	arg1	release					1011:1017	a sustained release	999:1017	a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs	999:1065	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	1	4	theme	complex	169:175	arg1	cascade					177:183	a complex cascade	167:183	a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs	167:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	4	theme	complex	169:175	arg1	healing					156:162	Bone healing	151:162	Bone healing	151:162	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	4	5	theme	TCP	1094:1096	arg1	scaffold					1098:1105	TCP scaffold	1094:1105	TCP scaffold	1094:1105	The composite coating and TCP scaffold can be conjugated due to the excellent adhesive property of PDA.					
36565172	0	6	theme	protein-2	110:118	arg1	release					120:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release	44:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration	44:148	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	1	7	theme	varying	360:366	arg1	types					368:372	varying types	360:372	varying types	360:372	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	5	8	theme	sustained	1236:1244	arg1	release					1246:1252	sustained release	1236:1252	sustained release of BMP-2, which can activate GFs for accelerating bone healing	1236:1315	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	2	9	theme	phosphate	625:633	arg1	scaffold					641:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	3	10	from	vascularization	868:882	arg1	stages					905:910	early bone repair stages	887:910	early bone repair stages	887:910	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	0	11	theme	morphogenetic	96:108	arg1	protein-2					110:118	bone morphogenetic protein-2	91:118	bone morphogenetic protein-2	91:118	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	3	12	theme	bone	965:968	arg1	formation					970:978	bone formation	965:978	bone formation	965:978	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	2	13	theme	calcium	617:623	arg1	scaffold					641:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	14	theme	alginate	765:772	arg1	PLL/OALG-NPs					789:800	PLL/OALG-NPs	789:800	PLL/OALG-NPs	789:800	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	14	theme	alginate	765:772	arg1	nanoparticles					774:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles	729:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs)	729:801	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	1	15	theme	osteogenic	289:298	arg1	GFs					315:317	osteogenic and angiogenic GFs	289:317	osteogenic and angiogenic GFs	289:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	2	16	theme	bone	506:509	arg1	BMP-2					536:540	BMP-2	536:540	BMP-2	536:540	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	16	theme	bone	506:509	arg1	protein-2					525:533	bone morphogenetic protein-2	506:533	bone morphogenetic protein-2 (BMP-2)	506:541	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	3	17	theme	due	912:914	arg1	vascularization					868:882	vascularization	868:882	vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs	868:956	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	2	18	theme	-decorated	597:606	arg1	scaffold					641:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	19	theme	tertiary	608:615	arg1	scaffold					641:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	20	theme	poly-L-lysine/oxidized	742:763	arg1	PLL/OALG-NPs					789:800	PLL/OALG-NPs	789:800	PLL/OALG-NPs	789:800	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	20	theme	poly-L-lysine/oxidized	742:763	arg1	nanoparticles					774:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles	729:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs)	729:801	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	21	theme	tunable	452:458	arg1	VEGF					496:499	VEGF	496:499	VEGF	496:499	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	21	theme	tunable	452:458	arg1	factor					488:493	tunable vascular endothelial growth factor	452:493	tunable vascular endothelial growth factor (VEGF)	452:500	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	22	theme	growth	481:486	arg1	VEGF					496:499	VEGF	496:499	VEGF	496:499	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	22	theme	growth	481:486	arg1	factor					488:493	tunable vascular endothelial growth factor	452:493	tunable vascular endothelial growth factor (VEGF)	452:500	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	4	23	theme	PDA	1167:1169	arg1	property					1155:1162	the excellent adhesive property	1132:1162	the excellent adhesive property of PDA	1132:1169	The composite coating and TCP scaffold can be conjugated due to the excellent adhesive property of PDA.					
36565172	2	24	theme	BMP-2-loaded	729:740	arg1	PLL/OALG-NPs					789:800	PLL/OALG-NPs	789:800	PLL/OALG-NPs	789:800	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	24	theme	BMP-2-loaded	729:740	arg1	nanoparticles					774:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles	729:786	BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs)	729:801	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	5	25	theme	BMP-2	1257:1261	arg1	release					1246:1252	sustained release	1236:1252	sustained release of BMP-2, which can activate GFs for accelerating bone healing	1236:1315	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	5	25	theme	BMP-2	1257:1261	arg1	release					1216:1222	the rapid release	1206:1222	the rapid release of VEGF	1206:1230	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	2	26	theme	scaffold	641:648	arg1	surface					566:572	the surface	562:572	the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	562:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	1	27	theme	coordinated	205:215	arg1	presentation					232:243	precisely coordinated spatiotemporal presentation	195:243	precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs	195:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	2	28	theme	composite	425:433	arg1	nanocoating					435:445	a composite nanocoating	423:445	a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs)	423:801	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	1	29	theme	angiogenic	304:313	arg1	GFs					315:317	osteogenic and angiogenic GFs	289:317	osteogenic and angiogenic GFs	289:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	2	30	theme	TCP	636:638	arg1	scaffold					641:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold	577:648	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	3	31	theme	CS/BSA-NPs	947:956	arg1	biodegradation					929:942	the rapid biodegradation	919:942	the rapid biodegradation of CS/BSA-NPs	919:956	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	1	32	theme	spatiotemporal	217:230	arg1	presentation					232:243	precisely coordinated spatiotemporal presentation	195:243	precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs	195:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	0	33	theme	composite	20:28	arg1	coatings					30:37	composite coatings	20:37	composite coatings	20:37	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	0	34	theme	bone	132:135	arg1	regeneration					137:148	bone regeneration	132:148	bone regeneration	132:148	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	1	35	theme	GFs	389:391	arg1	content					378:384	content	378:384	content of GFs	378:391	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	35	theme	GFs	389:391	arg1	types					368:372	varying types	360:372	varying types	360:372	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	2	36	theme	vascular	460:467	arg1	VEGF					496:499	VEGF	496:499	VEGF	496:499	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	36	theme	vascular	460:467	arg1	factor					488:493	tunable vascular endothelial growth factor	452:493	tunable vascular endothelial growth factor (VEGF)	452:500	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	0	37	theme	tunable	44:50	arg1	release					120:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release	44:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration	44:148	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	5	38	theme	composite	1176:1184	arg1	coating					1186:1192	The composite coating	1172:1192	The composite coating	1172:1192	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	3	39	theme	rapid	923:927	arg1	biodegradation					929:942	the rapid biodegradation	919:942	the rapid biodegradation of CS/BSA-NPs	919:956	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	2	40	theme	endothelial	469:479	arg1	VEGF					496:499	VEGF	496:499	VEGF	496:499	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	40	theme	endothelial	469:479	arg1	factor					488:493	tunable vascular endothelial growth factor	452:493	tunable vascular endothelial growth factor (VEGF)	452:500	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	41	theme	albumin	690:696	arg1	CS/BSA-NPs					713:722	CS/BSA-NPs	713:722	CS/BSA-NPs	713:722	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	41	theme	albumin	690:696	arg1	nanoparticles					698:710	VEGF-loaded chitosan/bovine serum albumin nanoparticles	656:710	VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs)	656:723	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	1	42	theme	multiple	248:255	arg1	GFs					315:317	osteogenic and angiogenic GFs	289:317	osteogenic and angiogenic GFs	289:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	42	theme	multiple	248:255	arg1	GFs					273:275	GFs	273:275	GFs	273:275	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	42	theme	multiple	248:255	arg1	factors					264:270	multiple growth factors	248:270	multiple growth factors (GFs)	248:276	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	0	43	theme	endothelial	61:71	arg1	factor					80:85	vascular endothelial growth factor	52:85	vascular endothelial growth factor	52:85	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	2	44	theme	serum	684:688	arg1	albumin					690:696	VEGF-loaded chitosan/bovine serum albumin	656:696	VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs)	656:723	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	0	45	theme	vascular	52:59	arg1	factor					80:85	vascular endothelial growth factor	52:85	vascular endothelial growth factor	52:85	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	3	46	from	PLL/OALG-NPs	1054:1065	arg1	release					1011:1017	a sustained release	999:1017	a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs	999:1065	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	5	47	theme	bone	1304:1307	arg1	healing					1309:1315	bone healing	1304:1315	bone healing	1304:1315	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	2	48	theme	chitosan/bovine	668:682	arg1	albumin					690:696	VEGF-loaded chitosan/bovine serum albumin	656:696	VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs)	656:723	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	4	49	theme	composite	1072:1080	arg1	coating					1082:1088	The composite coating	1068:1088	The composite coating	1068:1088	The composite coating and TCP scaffold can be conjugated due to the excellent adhesive property of PDA.					
36565172	3	50	theme	BMP-2	1022:1026	arg1	release					1011:1017	a sustained release	999:1017	a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs	999:1065	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	3	51	theme	repair	898:903	arg1	stages					905:910	early bone repair stages	887:910	early bone repair stages	887:910	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	2	52	theme	VEGF-loaded	656:666	arg1	albumin					690:696	VEGF-loaded chitosan/bovine serum albumin	656:696	VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs)	656:723	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	1	53	theme	growth	257:262	arg1	GFs					315:317	osteogenic and angiogenic GFs	289:317	osteogenic and angiogenic GFs	289:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	53	theme	growth	257:262	arg1	GFs					273:275	GFs	273:275	GFs	273:275	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	53	theme	growth	257:262	arg1	factors					264:270	multiple growth factors	248:270	multiple growth factors (GFs)	248:276	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	2	54	with	nanocoating	435:445	arg1	VEGF					496:499	VEGF	496:499	VEGF	496:499	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	54	with	nanocoating	435:445	arg1	factor					488:493	tunable vascular endothelial growth factor	452:493	tunable vascular endothelial growth factor (VEGF)	452:500	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	54	with	nanocoating	435:445	arg1	BMP-2					536:540	BMP-2	536:540	BMP-2	536:540	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	54	with	nanocoating	435:445	arg1	protein-2					525:533	bone morphogenetic protein-2	506:533	bone morphogenetic protein-2 (BMP-2)	506:541	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	3	55	theme	degrading	1044:1052	arg1	PLL/OALG-NPs					1054:1065	the slowly degrading PLL/OALG-NPs	1033:1065	the slowly degrading PLL/OALG-NPs	1033:1065	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	4	56	theme	adhesive	1146:1153	arg1	property					1155:1162	the excellent adhesive property	1132:1162	the excellent adhesive property of PDA	1132:1169	The composite coating and TCP scaffold can be conjugated due to the excellent adhesive property of PDA.					
36565172	1	57	theme	Bone	151:154	arg1	cascade					177:183	a complex cascade	167:183	a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs	167:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	57	theme	Bone	151:154	arg1	healing					156:162	Bone healing	151:162	Bone healing	151:162	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	1	58	theme	factors	264:270	arg1	presentation					232:243	precisely coordinated spatiotemporal presentation	195:243	precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs	195:317	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	0	59	theme	factor	80:85	arg1	release					120:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release	44:126	tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration	44:148	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	4	60	theme	excellent	1136:1144	arg1	property					1155:1162	the excellent adhesive property	1132:1162	the excellent adhesive property of PDA	1132:1169	The composite coating and TCP scaffold can be conjugated due to the excellent adhesive property of PDA.					
36565172	0	61	theme	growth	73:78	arg1	factor					80:85	vascular endothelial growth factor	52:85	vascular endothelial growth factor	52:85	Nanoparticles based composite coatings with tunable vascular endothelial growth factor and bone morphogenetic protein-2 release for bone regeneration.					
36565172	1	62	theme	bone	338:341	arg1	healing					343:349	bone healing	338:349	bone healing	338:349	Bone healing is a complex cascade involving precisely coordinated spatiotemporal presentation of multiple growth factors (GFs), including osteogenic and angiogenic GFs, and each stage of bone healing requires varying types and content of GFs.					
36565172	5	63	theme	VEGF	1227:1230	arg1	release					1246:1252	sustained release	1236:1252	sustained release of BMP-2, which can activate GFs for accelerating bone healing	1236:1315	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	5	63	theme	VEGF	1227:1230	arg1	release					1216:1222	the rapid release	1206:1222	the rapid release of VEGF	1206:1230	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	5	64	theme	rapid	1210:1214	arg1	release					1216:1222	the rapid release	1206:1222	the rapid release of VEGF	1206:1230	The composite coating can achieve the rapid release of VEGF and sustained release of BMP-2, which can activate GFs for accelerating bone healing.					
36565172	3	65	theme	early	887:891	arg1	stages					905:910	early bone repair stages	887:910	early bone repair stages	887:910	It was found that VEGF could be efficiently released to promote vascularization in early bone repair stages due to the rapid biodegradation of CS/BSA-NPs, while bone formation can be promoted by a sustained release of BMP-2 from the slowly degrading PLL/OALG-NPs.					
36565172	2	66	theme	morphogenetic	511:523	arg1	BMP-2					536:540	BMP-2	536:540	BMP-2	536:540	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
36565172	2	66	theme	morphogenetic	511:523	arg1	protein-2					525:533	bone morphogenetic protein-2	506:533	bone morphogenetic protein-2 (BMP-2)	506:541	In this study, we fabricated a composite nanocoating with tunable vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) that was coated on the surface of a polydopamine (PDA)-decorated tertiary calcium phosphate (TCP) scaffold using VEGF-loaded chitosan/bovine serum albumin nanoparticles (CS/BSA-NPs) and BMP-2-loaded poly-L-lysine/oxidized alginate nanoparticles (PLL/OALG-NPs).					
35981423	8	0	theme	nanocomposites	1048:1061	arg1	reinforcement					1013:1025	Significant reinforcement	1001:1025	Significant reinforcement of the medical-grade nanocomposites	1001:1061	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	3	1	theme	fabricated	401:410	arg1	materials					426:434	The fabricated nanocomposite materials	397:434	The fabricated nanocomposite materials	397:434	The fabricated nanocomposite materials were introduced in an SLA 3D printer for specimens manufacturing.					
35981423	4	2	theme	mechanical	506:515	arg1	performance					517:527	The mechanical performance	502:527	The mechanical performance	502:527	The mechanical performance was studied according to international standards.					
35981423	8	3	theme	medical-grade	1034:1046	arg1	nanocomposites					1048:1061	the medical-grade nanocomposites	1030:1061	the medical-grade nanocomposites	1030:1061	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	7	4	theme	Mechanical	974:983	arg1	DMA					995:997	DMA	995:997	DMA	995:997	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	7	4	theme	Mechanical	974:983	arg1	Analysis					985:992	Dynamic Mechanical Analysis	966:992	Dynamic Mechanical Analysis (DMA)	966:998	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	1	5	theme	medical-grade	155:167	arg1	resin					169:173	a medical-grade resin	153:173	a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology	153:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	7	6	theme	Thermogravimetric	896:912	arg1	TGA					924:926	TGA	924:926	TGA	924:926	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	7	6	theme	Thermogravimetric	896:912	arg1	Analysis					914:921	Thermogravimetric Analysis	896:921	Thermogravimetric Analysis (TGA)	896:927	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	2	7	with	ratios	371:376	arg1	resin					390:394	liquid resin	383:394	liquid resin	383:394	CNFs were shear stir blended at various weight ratios with liquid resin.					
35981423	6	8	theme	Scanning	747:754	arg1	Microscopy					765:774	Scanning Electron Microscopy	747:774	Scanning Electron Microscopy (SEM)	747:780	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	6	8	theme	Scanning	747:754	arg1	SEM					777:779	SEM	777:779	SEM	777:779	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	7	9	theme	thermal	835:841	arg1	properties					864:873	The thermal and thermomechanical properties	831:873	The thermal and thermomechanical properties	831:873	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	8	10	theme	tensile	1165:1171	arg1	strength					1173:1180	the tensile strength	1161:1180	the tensile strength	1161:1180	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	7	11	theme	Dynamic	966:972	arg1	DMA					995:997	DMA	995:997	DMA	995:997	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	7	11	theme	Dynamic	966:972	arg1	Analysis					985:992	Dynamic Mechanical Analysis	966:992	Dynamic Mechanical Analysis (DMA)	966:998	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	1	12	theme	Stereolithography	178:194	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	1	13	dep	processable	284:294	arg1	stiff					304:308	stiff	304:308	stiff	304:308	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	5	14	theme	tested	646:651	arg1	materials					653:661	all tested materials	642:661	all tested materials	642:661	Charpy Toughness and Vickers microhardness were calculated for all tested materials.					
35981423	5	15	theme	Charpy	579:584	arg1	Toughness					586:594	Charpy Toughness	579:594	Charpy Toughness	579:594	Charpy Toughness and Vickers microhardness were calculated for all tested materials.					
35981423	6	16	theme	tensile	726:732	arg1	specimens					734:742	fractured tensile specimens	716:742	fractured tensile specimens	716:742	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	0	17	theme	medical-grade	17:29	arg1	resin					31:35	High-performance medical-grade resin	0:35	High-performance medical-grade resin	0:35	High-performance medical-grade resin radically reinforced with cellulose nanofibers for 3D printing.					
35981423	8	18	theme	highest	1085:1091	arg1	values					1093:1098	the highest values	1081:1098	the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength)	1081:1181	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	8	19	theme	Significant	1001:1011	arg1	reinforcement					1013:1025	Significant reinforcement	1001:1025	Significant reinforcement of the medical-grade nanocomposites	1001:1061	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	6	20	theme	fractured	716:724	arg1	specimens					734:742	fractured tensile specimens	716:742	fractured tensile specimens	716:742	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	2	21	theme	weight	364:369	arg1	ratios					371:376	various weight ratios	356:376	various weight ratios with liquid resin	356:394	CNFs were shear stir blended at various weight ratios with liquid resin.					
35981423	0	22	theme	High-performance	0:15	arg1	resin					31:35	High-performance medical-grade resin	0:35	High-performance medical-grade resin	0:35	High-performance medical-grade resin radically reinforced with cellulose nanofibers for 3D printing.					
35981423	4	23	theme	international	554:566	arg1	standards					568:576	international standards	554:576	international standards	554:576	The mechanical performance was studied according to international standards.					
35981423	2	24	theme	various	356:362	arg1	ratios					371:376	various weight ratios	356:376	various weight ratios with liquid resin	356:394	CNFs were shear stir blended at various weight ratios with liquid resin.					
35981423	5	25	theme	Vickers	600:606	arg1	microhardness					608:620	Vickers microhardness	600:620	Vickers microhardness	600:620	Charpy Toughness and Vickers microhardness were calculated for all tested materials.					
35981423	7	26	theme	thermomechanical	847:862	arg1	properties					864:873	The thermal and thermomechanical properties	831:873	The thermal and thermomechanical properties	831:873	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	1	27	theme	SLA	197:199	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	1	28	theme	Cellulose	115:123	arg1	CNF					136:138	CNF	136:138	CNF	136:138	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	1	28	theme	Cellulose	115:123	arg1	NanoFiber					125:133	Cellulose NanoFiber	115:133	Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology	115:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	3	29	theme	SLA	458:460	arg1	printer					465:471	an SLA 3D printer	455:471	an SLA 3D printer for specimens manufacturing	455:499	The fabricated nanocomposite materials were introduced in an SLA 3D printer for specimens manufacturing.					
35981423	3	30	theme	nanocomposite	412:424	arg1	materials					426:434	The fabricated nanocomposite materials	397:434	The fabricated nanocomposite materials	397:434	The fabricated nanocomposite materials were introduced in an SLA 3D printer for specimens manufacturing.					
35981423	1	31	theme	Additive	202:209	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	7	32	theme	Differential	930:941	arg1	DSC					956:958	DSC	956:958	DSC	956:958	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	7	32	theme	Differential	930:941	arg1	Calorimetry					943:953	Differential Calorimetry	930:953	Differential Calorimetry (DSC)	930:959	The thermal and thermomechanical properties were investigated by Thermogravimetric Analysis (TGA), Differential Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA).					
35981423	1	33	theme	processable	284:294	arg1	bio-compound					310:321	an easily processable, highly stiff bio-compound	274:321	an easily processable, highly stiff bio-compound	274:321	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	6	34	theme	Atomic	786:791	arg1	AFM					811:813	AFM	811:813	AFM	811:813	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	6	34	theme	Atomic	786:791	arg1	Microscopy					799:808	Atomic Force Microscopy	786:808	Atomic Force Microscopy (AFM)	786:814	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	1	35	theme	Manufacturing	211:223	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	8	36	theme	1.0 wt	1120:1125	arg1	concentration					1128:1140	1.0 wt% concentration	1120:1140	1.0 wt% concentration (more than 100% at the tensile strength)	1120:1181	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	1	37	theme	NanoFiber	125:133	arg1	addition					141:148	Cellulose NanoFiber (CNF) addition	115:148	Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology	115:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	0	38	theme	cellulose	63:71	arg1	nanofibers					73:82	cellulose nanofibers	63:82	cellulose nanofibers for 3D printing	63:98	High-performance medical-grade resin radically reinforced with cellulose nanofibers for 3D printing.					
35981423	3	39	theme	specimens	477:485	arg1	manufacturing					487:499	specimens manufacturing	477:499	specimens manufacturing	477:499	The fabricated nanocomposite materials were introduced in an SLA 3D printer for specimens manufacturing.					
35981423	6	40	theme	surface	682:688	arg1	analysis					690:697	A microscopic and surface analysis	664:697	analysis	690:697	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	6	41	theme	Force	793:797	arg1	AFM					811:813	AFM	811:813	AFM	811:813	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	6	41	theme	Force	793:797	arg1	Microscopy					799:808	Atomic Force Microscopy	786:808	Atomic Force Microscopy (AFM)	786:814	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	2	42	from	ratios	371:376	arg1	blended					345:351	blended	345:351	blended	345:351	CNFs were shear stir blended at various weight ratios with liquid resin.					
35981423	3	43	theme	3D	462:463	arg1	printer					465:471	an SLA 3D printer	455:471	an SLA 3D printer for specimens manufacturing	455:499	The fabricated nanocomposite materials were introduced in an SLA 3D printer for specimens manufacturing.					
35981423	6	44	theme	Electron	756:763	arg1	Microscopy					765:774	Scanning Electron Microscopy	747:774	Scanning Electron Microscopy (SEM)	747:780	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	6	44	theme	Electron	756:763	arg1	SEM					777:779	SEM	777:779	SEM	777:779	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	8	45	theme	%	1126:1126	arg1	concentration					1128:1140	1.0 wt% concentration	1120:1140	1.0 wt% concentration (more than 100% at the tensile strength)	1120:1181	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	6	46	theme	microscopic	666:676	arg1	analysis					690:697	A microscopic and surface analysis	664:697	analysis	690:697	A microscopic and surface analysis was conducted on fractured tensile specimens by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM), respectively.					
35981423	1	47	theme	AM	226:227	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	0	48	theme	3D	88:89	arg1	printing					91:98	3D printing	88:98	3D printing	88:98	High-performance medical-grade resin radically reinforced with cellulose nanofibers for 3D printing.					
35981423	2	49	theme	liquid	383:388	arg1	resin					390:394	liquid resin	383:394	liquid resin	383:394	CNFs were shear stir blended at various weight ratios with liquid resin.					
35981423	1	50	theme	addition	141:148	arg1	effect					105:110	The effect	101:110	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology	101:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	8	51	from	strength	1173:1180	arg1	%					1156:1156	more than 100%	1143:1156	more than 100%	1143:1156	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35981423	1	52	from	resin	169:173	arg1	technology					230:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	Stereolithography (SLA) Additive Manufacturing (AM) technology	178:239	The effect of Cellulose NanoFiber (CNF) addition to a medical-grade resin in Stereolithography (SLA) Additive Manufacturing (AM) technology is reported, aiming to elaborate an easily processable, highly stiff bio-compound.					
35981423	8	53	dep	concentration	1128:1140	arg1	%					1156:1156	more than 100%	1143:1156	more than 100%	1143:1156	Significant reinforcement of the medical-grade nanocomposites is reported, with the highest values calculated to be at 1.0 wt% concentration (more than 100% at the tensile strength), while brittleness and rigidity were increased.					
35725155	0	0	theme	dodecyl	68:74	arg1	sulfate					76:82	sodium dodecyl sulfate	61:82	sodium dodecyl sulfate	61:82	A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate.					
35725155	3	1	theme	primary	709:715	arg1	complexes					731:739	primary electrostatic complexes	709:739	primary electrostatic complexes	709:739	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	4	2	from	formation	803:811	arg1	system					876:881	the binary chitosan/SDS system	852:881	the binary chitosan/SDS system	852:881	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	1	3	theme	system	142:147	arg1	Interaction					85:95	Interaction	85:95	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution	85:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	0	4	theme	sodium	61:66	arg1	sulfate					76:82	sodium dodecyl sulfate	61:82	sodium dodecyl sulfate	61:82	A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate.					
35725155	5	5	theme	cosmetic	1156:1163	arg1	compositions					1165:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	2	6	theme	CHI/SDS	340:346	arg1	complexes					348:356	insoluble CHI/SDS complexes	330:356	insoluble CHI/SDS complexes	330:356	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	4	7	theme	binding	989:995	arg1	mechanism					997:1005	a head-to-tail binding mechanism	974:1005	a head-to-tail binding mechanism with formation of elongated filamentous microstructures	974:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	8	from	aggregation	888:898	arg1	system					957:962	the ternary chitosan/NIS/SDS system	928:962	the ternary chitosan/NIS/SDS system	928:962	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	9	theme	nanoparticles	911:923	arg1	aggregation					888:898	the aggregation	884:898	the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system	884:962	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	1	10	theme	light	236:240	arg1	scattering					242:251	light scattering	236:251	light scattering	236:251	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	4	11	theme	head-to-tail	976:987	arg1	mechanism					997:1005	a head-to-tail binding mechanism	974:1005	a head-to-tail binding mechanism with formation of elongated filamentous microstructures	974:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	12	theme	complex	903:909	arg1	nanoparticles					911:923	complex nanoparticles	903:923	complex nanoparticles	903:923	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	2	13	theme	complexes	348:356	arg1	formation					317:325	The formation	313:325	The formation of insoluble CHI/SDS complexes	313:356	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	2	14	theme	NIS	491:493	arg1	concentration					495:507	NIS concentration	491:507	NIS concentration	491:507	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	2	15	theme	insoluble	330:338	arg1	complexes					348:356	insoluble CHI/SDS complexes	330:356	insoluble CHI/SDS complexes	330:356	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	3	16	theme	Soluble	510:516	arg1	complexes					531:539	Soluble chitosan/NIS complexes	510:539	Soluble chitosan/NIS complexes	510:539	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	1	17	theme	sodium	154:159	arg1	sulfate					169:175	sodium dodecyl sulfate	154:175	sodium dodecyl sulfate (SDS) in aqueous solution	154:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	1	17	theme	sodium	154:159	arg1	SDS					178:180	SDS	178:180	SDS	178:180	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	3	18	theme	electrostatic	717:729	arg1	complexes					731:739	primary electrostatic complexes	709:739	primary electrostatic complexes	709:739	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	4	19	theme	chitosan/SDS	863:874	arg1	system					876:881	the binary chitosan/SDS system	852:881	the binary chitosan/SDS system	852:881	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	3	20	theme	chitosan/NIS	518:529	arg1	complexes					531:539	Soluble chitosan/NIS complexes	510:539	Soluble chitosan/NIS complexes	510:539	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	5	21	theme	drug	1182:1185	arg1	systems					1196:1202	drug delivery systems	1182:1202	drug delivery systems containing mixed surfactants	1182:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	1	22	theme	dodecyl	161:167	arg1	sulfate					169:175	sodium dodecyl sulfate	154:175	sodium dodecyl sulfate (SDS) in aqueous solution	154:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	1	22	theme	dodecyl	161:167	arg1	SDS					178:180	SDS	178:180	SDS	178:180	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	0	23	theme	feasible	2:9	arg1	approach					11:18	A feasible approach	0:18	A feasible approach	0:18	A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate.					
35725155	3	24	theme	complexes	731:739	arg1	aggregation					694:704	aggregation	694:704	aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles	694:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	3	25	theme	hydrogen	745:752	arg1	bonding					754:760	hydrogen bonding	745:760	hydrogen bonding to complex nanoparticles	745:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	2	26	theme	micelle	431:437	arg1	concentration					439:451	critical micelle concentration	422:451	critical micelle concentration of NIS	422:458	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	3	27	theme	complex	765:771	arg1	nanoparticles					773:785	complex nanoparticles	765:785	complex nanoparticles	765:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	3	28	theme	molecular	665:673	arg1	weight					675:680	chitosan molecular weight	656:680	chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles	656:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	4	29	dep	formation	803:811	arg1	contrast					791:798	contrast	791:798	contrast	791:798	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	2	30	theme	critical	422:429	arg1	concentration					439:451	critical micelle concentration	422:451	critical micelle concentration of NIS	422:458	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	1	31	theme	electophoretic	254:267	arg1	mobility					269:276	electophoretic mobility	254:276	electophoretic mobility	254:276	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	4	32	theme	swarm-like	827:836	arg1	structures					838:847	asymmetric swarm-like structures	816:847	asymmetric swarm-like structures	816:847	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	3	33	theme	SDS	548:550	arg1	molecules					552:560	SDS molecules	548:560	SDS molecules	548:560	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	2	34	theme	chitosan	409:416	arg1	weight					399:404	molecular weight	389:404	molecular weight of chitosan	389:416	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	4	35	with	mechanism	997:1005	arg1	formation					1012:1020	formation	1012:1020	formation of elongated filamentous microstructures	1012:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	5	36	theme	mixed	1215:1219	arg1	surfactants					1221:1231	mixed surfactants	1215:1231	mixed surfactants	1215:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	5	37	theme	pharmaceutical	1137:1150	arg1	compositions					1165:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	5	38	contain	containing	1204:1213	arg2	surfactants					1221:1231	mixed surfactants	1215:1231	mixed surfactants	1215:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	5	38	contain	containing	1204:1213	arg1	systems					1196:1202	drug delivery systems	1182:1202	drug delivery systems containing mixed surfactants	1182:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	3	39	theme	mixed	582:586	arg1	complexes					605:613	mixed chitosan/NIS/SDS complexes	582:613	mixed chitosan/NIS/SDS complexes	582:613	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	4	40	theme	microstructures	1047:1061	arg1	formation					1012:1020	formation	1012:1020	formation of elongated filamentous microstructures	1012:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	1	41	theme	cryogenic	282:290	arg1	microscopy					301:310	cryogenic electron microscopy	282:310	cryogenic electron microscopy	282:310	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	2	42	from	increase	479:486	arg1	concentration					495:507	NIS concentration	491:507	NIS concentration	491:507	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	3	43	theme	chitosan/NIS/SDS	588:603	arg1	complexes					605:613	mixed chitosan/NIS/SDS complexes	582:613	mixed chitosan/NIS/SDS complexes	582:613	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	1	44	theme	aqueous	186:192	arg1	solution					194:201	aqueous solution	186:201	aqueous solution	186:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	2	45	theme	NIS	456:458	arg1	concentration					439:451	critical micelle concentration	422:451	critical micelle concentration of NIS	422:458	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	1	46	theme	electron	292:299	arg1	microscopy					301:310	cryogenic electron microscopy	282:310	cryogenic electron microscopy	282:310	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	5	47	theme	compositions	1165:1176	arg1	preparation					1097:1107	preparation	1097:1107	preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants	1097:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	4	48	theme	binary	856:861	arg1	system					876:881	the binary chitosan/SDS system	852:881	the binary chitosan/SDS system	852:881	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	5	49	theme	delivery	1187:1194	arg1	systems					1196:1202	drug delivery systems	1182:1202	drug delivery systems containing mixed surfactants	1182:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	1	50	theme	binary	100:105	arg1	system					142:147	binary chitosan/nonionic surfactant (NIS) system	100:147	binary chitosan/nonionic surfactant (NIS) system	100:147	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	5	51	theme	systems	1196:1202	arg1	preparation					1097:1107	preparation	1097:1107	preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants	1097:1231	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35725155	1	52	theme	chitosan/nonionic	107:123	arg1	system					142:147	binary chitosan/nonionic surfactant (NIS) system	100:147	binary chitosan/nonionic surfactant (NIS) system	100:147	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	4	53	theme	structures	838:847	arg1	formation					803:811	formation	803:811	formation of asymmetric swarm-like structures in the binary chitosan/SDS system	803:881	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	54	theme	chitosan/NIS/SDS	940:955	arg1	system					957:962	the ternary chitosan/NIS/SDS system	928:962	the ternary chitosan/NIS/SDS system	928:962	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	2	55	from	decrease	377:384	arg1	weight					399:404	molecular weight	389:404	molecular weight of chitosan	389:416	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	1	56	theme	surfactant	125:134	arg1	system					142:147	binary chitosan/nonionic surfactant (NIS) system	100:147	binary chitosan/nonionic surfactant (NIS) system	100:147	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	4	57	theme	elongated	1025:1033	arg1	microstructures					1047:1061	elongated filamentous microstructures	1025:1061	elongated filamentous microstructures	1025:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	58	theme	ternary	932:938	arg1	system					957:962	the ternary chitosan/NIS/SDS system	928:962	the ternary chitosan/NIS/SDS system	928:962	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	3	59	theme	chitosan	656:663	arg1	weight					675:680	chitosan molecular weight	656:680	chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles	656:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	3	60	theme	critical	625:632	arg1	value					634:638	a critical value	623:638	a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles	623:785	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	1	61	from	sulfate	169:175	arg1	solution					194:201	aqueous solution	186:201	aqueous solution	186:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	2	62	theme	molecular	389:397	arg1	weight					399:404	molecular weight	389:404	molecular weight of chitosan	389:416	The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration.					
35725155	3	63	theme	complexes	605:613	arg1	charge					572:577	the charge	568:577	the charge of mixed chitosan/NIS/SDS complexes	568:613	Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles.					
35725155	0	64	with	interaction	32:42	arg1	sulfate					76:82	sodium dodecyl sulfate	61:82	sodium dodecyl sulfate	61:82	A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate.					
35725155	1	65	theme	NIS	137:139	arg1	system					142:147	binary chitosan/nonionic surfactant (NIS) system	100:147	binary chitosan/nonionic surfactant (NIS) system	100:147	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	0	66	theme	chitosan	47:54	arg1	interaction					32:42	the interaction	28:42	the interaction of chitosan with sodium dodecyl sulfate	28:82	A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate.					
35725155	4	67	theme	filamentous	1035:1045	arg1	microstructures					1047:1061	elongated filamentous microstructures	1025:1061	elongated filamentous microstructures	1025:1061	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	4	68	theme	asymmetric	816:825	arg1	structures					838:847	asymmetric swarm-like structures	816:847	asymmetric swarm-like structures	816:847	In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures.					
35725155	1	69	with	Interaction	85:95	arg1	sulfate					169:175	sodium dodecyl sulfate	154:175	sodium dodecyl sulfate (SDS) in aqueous solution	154:201	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	1	69	with	Interaction	85:95	arg1	SDS					178:180	SDS	178:180	SDS	178:180	Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy.					
35725155	5	70	theme	stable	1130:1135	arg1	compositions					1165:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	microbiologically stable pharmaceutical and cosmetic compositions	1112:1176	The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.					
35700425	5	0	theme	doping	1206:1211	arg1	percentages					1213:1223	the doping percentages	1202:1223	the doping percentages of MOF in the membrane	1202:1246	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	0	theme	doping	1206:1211	arg1	Y					1189:1189	Y	1189:1189	Y	1189:1189	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	0	theme	doping	1206:1211	arg1	Z					1196:1196	Z	1196:1196	Z	1196:1196	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	0	theme	doping	1206:1211	arg1	X					1186:1186	X	1186:1186	X	1186:1186	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	7	1	theme	composite	1708:1716	arg1	membranes					1718:1726	related composite membranes	1700:1726	related composite membranes	1700:1726	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	2	2	theme	fumaric	539:545	arg1	acid					547:550	cheap fumaric acid	533:550	cheap fumaric acid	533:550	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	2	theme	fumaric	539:545	arg1	ligand					568:573	the bridging ligand	555:573	the bridging ligand	555:573	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	6	3	theme	CS/Im	1316:1320	arg1	MOF-801-Hf-4					1322:1333	CS/Im@MOF-801-Hf-4	1316:1333	CS/Im@MOF-801-Hf-4	1316:1333	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	1	4	theme	metal-organic	176:188	arg1	frameworks					190:199	Hafnium (Hf)-based UiO-66 series metal-organic frameworks	143:199	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs)	143:206	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	1	4	theme	metal-organic	176:188	arg1	MOFs					202:205	MOFs	202:205	MOFs	202:205	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	7	5	theme	Hf-based	1682:1689	arg1	MOFs					1691:1694	these Hf-based MOFs	1676:1694	these Hf-based MOFs	1676:1694	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	2	6	theme	bridging	559:566	arg1	acid					547:550	cheap fumaric acid	533:550	cheap fumaric acid	533:550	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	6	theme	bridging	559:566	arg1	ligand					568:573	the bridging ligand	555:573	the bridging ligand	555:573	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	7	theme	@	675:675	arg1	product					664:670	a doped product	656:670	a doped product	656:670	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	7	theme	@	675:675	arg1	MOF-801-Hf					676:685	Im@MOF-801-Hf	673:685	Im@MOF-801-Hf	673:685	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	0	8	theme	Membranes	132:140	arg1	Conductivities					34:47	the Proton Conductivities	23:47	the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes	23:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	4	9	theme	Im	848:849	arg1	MOF-801-Hf					851:860	Im@MOF-801-Hf	848:860	Im@MOF-801-Hf	848:860	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	10	theme	varying	1555:1561	arg1	degrees					1563:1569	varying degrees	1555:1569	varying degrees of enhancement	1555:1584	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	1	11	theme	few	357:359	arg1	studies					361:367	few studies	357:367	few studies on proton conductivity	357:390	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	4	12	theme	proton	821:826	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	12	theme	proton	821:826	arg1	times					895:899	times	895:899	times	895:899	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	12	theme	proton	821:826	arg1	S·cm-1					875:880	1.46 × 10-2 S·cm-1	863:880	1.46 × 10-2 S·cm-1	863:880	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	12	theme	proton	821:826	arg1	σ					842:842	σ	842:842	σ	842:842	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	13	theme	σ	1357:1357	arg1	values					1359:1364	the highest σ values	1345:1364	the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1	1345:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	3	14	theme	acid-base	774:782	arg1	stabilities					784:794	excellent thermal, water, and acid-base stabilities	744:794	excellent thermal, water, and acid-base stabilities	744:794	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	2	15	theme	room	510:513	arg1	temperature					515:525	room temperature	510:525	room temperature using cheap fumaric acid as the bridging ligand	510:573	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	6	16	dep	%	1438:1438	arg1	°C					1429:1430	°C	1429:1430	°C	1429:1430	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	6	16	dep	%	1438:1438	arg1	98					1436:1437	98	1436:1437	98	1436:1437	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	4	17	theme	10-2	870:873	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	17	theme	10-2	870:873	arg1	S·cm-1					875:880	1.46 × 10-2 S·cm-1	863:880	1.46 × 10-2 S·cm-1	863:880	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	18	theme	pure	1619:1622	arg1	CS					1624:1625	pure CS	1619:1625	pure CS	1619:1625	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	3	19	theme	Im	718:719	arg1	MOF-801-Hf					721:730	Im@MOF-801-Hf	718:730	Im@MOF-801-Hf	718:730	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	0	20	theme	Metal-Organic	66:78	arg1	Frameworks					80:89	Hafnium-Based Metal-Organic Frameworks	52:89	Hafnium-Based Metal-Organic Frameworks	52:89	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	2	21	theme	doped	658:662	arg1	product					664:670	a doped product	656:670	a doped product	656:670	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	21	theme	doped	658:662	arg1	MOF-801-Hf					676:685	Im@MOF-801-Hf	673:685	Im@MOF-801-Hf	673:685	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	7	22	theme	electrochemical	1753:1767	arg1	fields					1769:1774	electrochemical fields	1753:1774	electrochemical fields	1753:1774	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	6	23	theme	S·cm-1	1397:1402	arg1	values					1359:1364	the highest σ values	1345:1364	the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1	1345:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	4	24	theme	MOF-801-Hf	851:860	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	24	theme	MOF-801-Hf	851:860	arg1	times					895:899	times	895:899	times	895:899	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	24	theme	MOF-801-Hf	851:860	arg1	S·cm-1					875:880	1.46 × 10-2 S·cm-1	863:880	1.46 × 10-2 S·cm-1	863:880	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	24	theme	MOF-801-Hf	851:860	arg1	σ					842:842	σ	842:842	σ	842:842	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	2	25	theme	imidazole	585:593	arg1	units					595:599	imidazole units	585:599	imidazole units	585:599	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	3	26	theme	excellent	744:752	arg1	stabilities					784:794	excellent thermal, water, and acid-base stabilities	744:794	excellent thermal, water, and acid-base stabilities	744:794	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	0	27	theme	Chitosan	103:110	arg1	Membranes					132:140	Related Chitosan or Nafion Composite Membranes	95:140	Related Chitosan or Nafion Composite Membranes	95:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	6	28	theme	×	1390:1390	arg1	S·cm-1					1397:1402	2.14 × 10-2 S·cm-1	1385:1402	2.14 × 10-2 S·cm-1	1385:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	29	theme	CS/Im	1143:1147	arg1	fillers					1110:1116	fillers	1110:1116	fillers	1110:1116	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	29	theme	CS/Im	1143:1147	arg1	MOF-801-Hf-					1149:1159	CS/Im@MOF-801-Hf-	1143:1159	CS/Im@MOF-801-Hf-	1143:1159	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	0	30	theme	Nafion	115:120	arg1	Membranes					132:140	Related Chitosan or Nafion Composite Membranes	95:140	Related Chitosan or Nafion Composite Membranes	95:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	1	31	dep	-based	155:160	arg1	series					169:174	UiO-66 series	162:174	UiO-66 series	162:174	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	0	32	theme	Comparative	0:10	arg1	Studies					12:18	Comparative Studies	0:18	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.	0:141	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	6	33	theme	×	1374:1374	arg1	10-2					1376:1379	1.73 × 10-2	1369:1379	1.73 × 10-2	1369:1379	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	34	dep	Nafion/MOF-801-Hf-	1166:1183	arg1	percentages					1213:1223	the doping percentages	1202:1223	the doping percentages of MOF in the membrane	1202:1246	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	34	dep	Nafion/MOF-801-Hf-	1166:1183	arg1	Y					1189:1189	Y	1189:1189	Y	1189:1189	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	34	dep	Nafion/MOF-801-Hf-	1166:1183	arg1	Z					1196:1196	Z	1196:1196	Z	1196:1196	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	34	dep	Nafion/MOF-801-Hf-	1166:1183	arg1	X					1186:1186	X	1186:1186	X	1186:1186	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	6	35	theme	S·cm-1	1511:1516	arg1	value					1490:1494	a high σ value	1481:1494	a high σ value of 4.87 × 10-2 S·cm-1	1481:1516	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	36	theme	possible	1016:1023	arg1	value					1047:1051	their possible practical application value	1010:1051	their possible practical application value	1010:1051	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	6	37	theme	×	1504:1504	arg1	S·cm-1					1511:1516	4.87 × 10-2 S·cm-1	1499:1516	4.87 × 10-2 S·cm-1	1499:1516	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	0	38	theme	Proton	27:32	arg1	Conductivities					34:47	the Proton Conductivities	23:47	the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes	23:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	2	39	theme	Hf-based	411:418	arg1	Hf-UiO-66-fum					425:437	Hf-UiO-66-fum	425:437	Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf	425:488	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	39	theme	Hf-based	411:418	arg1	MOF					420:422	one Hf-based MOF	407:422	one Hf-based MOF	407:422	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	4	40	theme	×	868:868	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	40	theme	×	868:868	arg1	S·cm-1					875:880	1.46 × 10-2 S·cm-1	863:880	1.46 × 10-2 S·cm-1	863:880	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	41	theme	σ	1488:1488	arg1	value					1490:1494	a high σ value	1481:1494	a high σ value of 4.87 × 10-2 S·cm-1	1481:1516	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	7	42	from	potential	1740:1748	arg1	fields					1769:1774	electrochemical fields	1753:1774	electrochemical fields	1753:1774	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	4	43	dep	times	895:899	arg1	greater					901:907	greater	901:907	greater	901:907	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	5	44	theme	application	1035:1045	arg1	value					1047:1051	their possible practical application value	1010:1051	their possible practical application value	1010:1051	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	7	45	theme	great	1734:1738	arg1	potential					1740:1748	great potential	1734:1748	great potential in electrochemical fields	1734:1774	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	5	46	from	percentages	1213:1223	arg1	membrane					1239:1246	the membrane	1235:1246	the membrane	1235:1246	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	4	47	theme	×	939:939	arg1	S·cm-1					946:951	3.98 × 10-3 S·cm-1	934:951	3.98 × 10-3 S·cm-1	934:951	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	47	theme	×	939:939	arg1	MOF-801-Hf					922:931	MOF-801-Hf	922:931	MOF-801-Hf (3.98 × 10-3 S·cm-1)	922:952	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	48	theme	@	1321:1321	arg1	MOF-801-Hf-4					1322:1333	CS/Im@MOF-801-Hf-4	1316:1333	CS/Im@MOF-801-Hf-4	1316:1333	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	1	49	theme	gas	249:251	arg1	separation					253:262	gas separation	249:262	gas separation	249:262	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	2	50	theme	cheap	533:537	arg1	acid					547:550	cheap fumaric acid	533:550	cheap fumaric acid	533:550	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	50	theme	cheap	533:537	arg1	ligand					568:573	the bridging ligand	555:573	the bridging ligand	555:573	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	4	51	theme	relative	975:982	arg1	RH					994:995	RH	994:995	RH	994:995	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	51	theme	relative	975:982	arg1	humidity					984:991	100 °C and 98% relative humidity	960:991	100 °C and 98% relative humidity (RH)	960:996	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	5	52	theme	MOF	1228:1230	arg1	percentages					1213:1223	the doping percentages	1202:1223	the doping percentages of MOF in the membrane	1202:1246	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	52	theme	MOF	1228:1230	arg1	Y					1189:1189	Y	1189:1189	Y	1189:1189	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	52	theme	MOF	1228:1230	arg1	Z					1196:1196	Z	1196:1196	Z	1196:1196	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	52	theme	MOF	1228:1230	arg1	X					1186:1186	X	1186:1186	X	1186:1186	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	7	53	theme	related	1700:1706	arg1	membranes					1718:1726	related composite membranes	1700:1726	related composite membranes	1700:1726	Our study illustrates that these Hf-based MOFs and related composite membranes offer great potential in electrochemical fields.					
35700425	1	54	from	studies	361:367	arg1	conductivity					379:390	proton conductivity	372:390	proton conductivity	372:390	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	6	55	theme	enhancement	1574:1584	arg1	degrees					1563:1569	varying degrees	1555:1569	varying degrees of enhancement	1555:1584	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	4	56	theme	maximum	813:819	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	56	theme	maximum	813:819	arg1	times					895:899	times	895:899	times	895:899	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	56	theme	maximum	813:819	arg1	S·cm-1					875:880	1.46 × 10-2 S·cm-1	863:880	1.46 × 10-2 S·cm-1	863:880	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	56	theme	maximum	813:819	arg1	σ					842:842	σ	842:842	σ	842:842	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	6	57	theme	Nafion	1631:1636	arg1	membranes					1638:1646	pure CS and Nafion membranes	1619:1646	pure CS and Nafion membranes	1619:1646	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	58	theme	Nafion	1090:1095	arg1	membranes					1097:1105	Nafion membranes	1090:1105	Nafion membranes	1090:1105	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	1	59	theme	proton	372:377	arg1	conductivity					379:390	proton conductivity	372:390	proton conductivity	372:390	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	6	60	theme	highest	1349:1355	arg1	values					1359:1364	the highest σ values	1345:1364	the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1	1345:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	6	61	dep	RH	1440:1441	arg1	%					1438:1438	%	1438:1438	%	1438:1438	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	2	62	theme	Im	673:674	arg1	product					664:670	a doped product	656:670	a doped product	656:670	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	2	62	theme	Im	673:674	arg1	MOF-801-Hf					676:685	Im@MOF-801-Hf	673:685	Im@MOF-801-Hf	673:685	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	6	63	theme	CS	1624:1625	arg1	membranes					1638:1646	pure CS and Nafion membranes	1619:1646	pure CS and Nafion membranes	1619:1646	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	0	64	theme	Frameworks	80:89	arg1	Conductivities					34:47	the Proton Conductivities	23:47	the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes	23:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	4	65	dep	humidity	984:991	arg1	%					973:973	%	973:973	%	973:973	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	2	66	theme	UiO-66	447:452	arg1	structure					454:462	UiO-66 structure	447:462	UiO-66 structure	447:462	In this work, one Hf-based MOF, Hf-UiO-66-fum showing UiO-66 structure, also known as MOF-801-Hf, was synthesized at room temperature using cheap fumaric acid as the bridging ligand, and then imidazole units were successfully introduced into MOF-801-Hf to obatin a doped product, Im@MOF-801-Hf.					
35700425	6	67	theme	high	1483:1486	arg1	value					1490:1494	a high σ value	1481:1494	a high σ value of 4.87 × 10-2 S·cm-1	1481:1516	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	3	68	theme	@	720:720	arg1	MOF-801-Hf					721:730	Im@MOF-801-Hf	718:730	Im@MOF-801-Hf	718:730	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	0	69	theme	Related	95:101	arg1	Membranes					132:140	Related Chitosan or Nafion Composite Membranes	95:140	Related Chitosan or Nafion Composite Membranes	95:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	4	70	dep	%	973:973	arg1	98					971:972	98	971:972	98	971:972	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	70	dep	%	973:973	arg1	°C					964:965	°C	964:965	°C	964:965	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	1	71	theme	-based	155:160	arg1	frameworks					190:199	Hafnium (Hf)-based UiO-66 series metal-organic frameworks	143:199	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs)	143:206	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	1	71	theme	-based	155:160	arg1	MOFs					202:205	MOFs	202:205	MOFs	202:205	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	0	72	from	Studies	12:18	arg1	Conductivities					34:47	the Proton Conductivities	23:47	the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes	23:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	6	73	theme	original	1602:1609	arg1	MOFs					1611:1614	the original MOFs	1598:1614	the original MOFs	1598:1614	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	3	74	theme	water	763:767	arg1	stabilities					784:794	excellent thermal, water, and acid-base stabilities	744:794	excellent thermal, water, and acid-base stabilities	744:794	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	6	75	theme	10-2	1392:1395	arg1	S·cm-1					1397:1402	2.14 × 10-2 S·cm-1	1385:1402	2.14 × 10-2 S·cm-1	1385:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	4	76	theme	@	850:850	arg1	MOF-801-Hf					851:860	Im@MOF-801-Hf	848:860	Im@MOF-801-Hf	848:860	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	3	77	theme	thermal	754:760	arg1	stabilities					784:794	excellent thermal, water, and acid-base stabilities	744:794	excellent thermal, water, and acid-base stabilities	744:794	Note that both MOF-801-Hf and Im@MOF-801-Hf demonstrate excellent thermal, water, and acid-base stabilities.					
35700425	0	78	theme	Composite	122:130	arg1	Membranes					132:140	Related Chitosan or Nafion Composite Membranes	95:140	Related Chitosan or Nafion Composite Membranes	95:140	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	6	79	theme	2.14	1385:1388	arg1	S·cm-1					1397:1402	2.14 × 10-2 S·cm-1	1385:1402	2.14 × 10-2 S·cm-1	1385:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	80	theme	@	1148:1148	arg1	fillers					1110:1116	fillers	1110:1116	fillers	1110:1116	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	5	80	theme	@	1148:1148	arg1	MOF-801-Hf-					1149:1159	CS/Im@MOF-801-Hf-	1143:1159	CS/Im@MOF-801-Hf-	1143:1159	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	6	81	theme	10-2	1376:1379	arg1	values					1359:1364	the highest σ values	1345:1364	the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1	1345:1402	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	1	82	theme	reduction	265:273	arg1	reaction					275:282	reduction reaction	265:282	reduction reaction	265:282	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	6	83	theme	10-2	1506:1509	arg1	S·cm-1					1511:1516	4.87 × 10-2 S·cm-1	1499:1516	4.87 × 10-2 S·cm-1	1499:1516	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	5	84	theme	practical	1025:1033	arg1	value					1047:1051	their possible practical application value	1010:1051	their possible practical application value	1010:1051	To explore their possible practical application value, we doped them into chitosan (CS) or Nafion membranes as fillers, namely, CS/MOF-801-Hf-, CS/Im@MOF-801-Hf-, and Nafion/MOF-801-Hf- (X, Y, and Z are the doping percentages of MOF in the membrane, respectively).					
35700425	6	85	theme	4.87	1499:1502	arg1	×					1504:1504	×	1504:1504	×	1504:1504	Intriguingly, it was found that CS/MOF-801-Hf-6 and CS/Im@MOF-801-Hf-4 indicated the highest σ values of 1.73 × 10-2 and 2.14 × 10-2 S·cm-1, respectively, under 100 °C and 98% RH and Nafion/MOF-801-Hf-9 also revealed a high σ value of 4.87 × 10-2 S·cm-1 under 80 °C and 98% RH, which showed varying degrees of enhancement compared to the original MOFs or pure CS and Nafion membranes.					
35700425	0	86	theme	Hafnium-Based	52:64	arg1	Frameworks					80:89	Hafnium-Based Metal-Organic Frameworks	52:89	Hafnium-Based Metal-Organic Frameworks	52:89	Comparative Studies on the Proton Conductivities of Hafnium-Based Metal-Organic Frameworks and Related Chitosan or Nafion Composite Membranes.					
35700425	1	87	theme	other	289:293	arg1	aspects					295:301	other aspects	289:301	other aspects	289:301	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
35700425	4	88	theme	4	893:893	arg1	conductivity					828:839	the maximum proton conductivity	809:839	the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1)	809:881	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	88	theme	4	893:893	arg1	times					895:899	times	895:899	times	895:899	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	89	theme	10-3	941:944	arg1	S·cm-1					946:951	3.98 × 10-3 S·cm-1	934:951	3.98 × 10-3 S·cm-1	934:951	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	4	89	theme	10-3	941:944	arg1	MOF-801-Hf					922:931	MOF-801-Hf	922:931	MOF-801-Hf (3.98 × 10-3 S·cm-1)	922:952	Expectedly, the maximum proton conductivity (σ) of Im@MOF-801-Hf (1.46 × 10-2 S·cm-1) is nearly 4 times greater than that of MOF-801-Hf (3.98 × 10-3 S·cm-1) under 100 °C and 98% relative humidity (RH).					
35700425	1	90	theme	gas	236:238	arg1	storage					240:246	gas storage	236:246	gas storage	236:246	Hafnium (Hf)-based UiO-66 series metal-organic frameworks (MOFs) have been widely studied on gas storage, gas separation, reduction reaction, and other aspects since they were first prepared in 2012, but there are few studies on proton conductivity.					
36583973	0	0	theme	Mild-Temperature	77:92	arg1	Disinfection					113:124	Mild-Temperature Photothermal-Chemo Disinfection	77:124	Mild-Temperature Photothermal-Chemo Disinfection	77:124	When Iodine Meets Starch: On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection.					
36583973	2	1	theme	possible	389:396	arg1	damage					398:403	the possible damage	385:403	the possible damage to normal tissue caused by hyperthermia	385:443	However, the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia restrict its applications.					
36583973	5	2	theme	convenient	843:852	arg1	response					857:864	a convenient pH response	841:864	a convenient pH response	841:864	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	3	3	theme	generation	542:551	arg1	ability					521:527	the ability	517:527	the ability of on-demand generation of photothermal components	517:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	5	4	theme	combined	1075:1082	arg1	disinfection					1084:1095	photothermal-chemotherapy combined disinfection	1049:1095	photothermal-chemotherapy combined disinfection on demand	1049:1105	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	4	5	theme	iodine-adsorbed	740:754	arg1	NPs					791:793	NPs	791:793	NPs	791:793	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	4	5	theme	iodine-adsorbed	740:754	arg1	nanoparticles					776:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles	740:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix	740:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	3	6	theme	mild-temperature	584:599	arg1	disinfection					614:625	mild-temperature photothermal disinfection	584:625	mild-temperature photothermal disinfection by elegantly tuning	584:645	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	4	7	theme	hydrogel	816:823	arg1	matrix					825:830	a starch-based hydrogel matrix	801:830	a starch-based hydrogel matrix	801:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	1	8	theme	non-drug	283:290	arg1	resistance					292:301	non-drug resistance	283:301	non-drug resistance	283:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	0	9	theme	Photothermal-Chemo	94:111	arg1	Disinfection					113:124	Mild-Temperature Photothermal-Chemo Disinfection	77:124	Mild-Temperature Photothermal-Chemo Disinfection	77:124	When Iodine Meets Starch: On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection.					
36583973	4	10	with	nanoparticles	776:788	arg1	matrix					825:830	a starch-based hydrogel matrix	801:830	a starch-based hydrogel matrix	801:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	3	11	theme	photothermal	601:612	arg1	disinfection					614:625	mild-temperature photothermal disinfection	584:625	mild-temperature photothermal disinfection by elegantly tuning	584:645	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	6	12	theme	naked-eye	1315:1323	arg1	observation					1325:1335	naked-eye observation	1315:1335	naked-eye observation	1315:1335	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	3	13	theme	on-demand	532:540	arg1	generation					542:551	on-demand generation	532:551	on-demand generation of photothermal components	532:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	5	14	from	disinfection	1084:1095	arg1	demand					1100:1105	demand	1100:1105	demand	1100:1105	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	1	15	theme	resistance	292:301	arg1	advantages					233:242	its advantages	229:242	its advantages of high efficacy, wide pertinence, and non-drug resistance	229:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	4	16	theme	ZIF-8	770:774	arg1	NPs					791:793	NPs	791:793	NPs	791:793	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	4	16	theme	ZIF-8	770:774	arg1	nanoparticles					776:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles	740:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix	740:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	4	17	theme	starch-based	803:814	arg1	matrix					825:830	a starch-based hydrogel matrix	801:830	a starch-based hydrogel matrix	801:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	3	18	theme	components	569:578	arg1	generation					542:551	on-demand generation	532:551	on-demand generation of photothermal components	532:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	6	19	theme	composite	1157:1165	arg1	hydrogel					1167:1174	the composite hydrogel	1153:1174	the composite hydrogel	1153:1174	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	1	20	theme	increasing	201:210	arg1	strategy					156:163	an emerging antibacterial strategy	130:163	an emerging antibacterial strategy	130:163	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	20	theme	increasing	201:210	arg1	attention					212:220	increasing attention	201:220	increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance	201:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	5	21	theme	composite	871:879	arg1	hydrogel					881:888	the composite hydrogel	867:888	the composite hydrogel	867:888	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	5	22	theme	pH	854:855	arg1	response					857:864	a convenient pH response	841:864	a convenient pH response	841:864	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	6	23	theme	In	1108:1109	arg1	experiments					1131:1141	In vitro antibacterial experiments	1108:1141	In vitro antibacterial experiments	1108:1141	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	3	24	dep	binding	651:657	arg1	the					647:649	the	647:649	the	647:649	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	3	25	with	disinfection	614:625	arg1	ability					521:527	the ability	517:527	the ability of on-demand generation of photothermal components	517:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	6	26	dep	In	1108:1109	arg1	vitro					1111:1115	vitro	1111:1115	vitro	1111:1115	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	2	27	theme	observation	342:352	arg1	shielding					329:337	the unavoidable shielding	313:337	the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia	313:443	However, the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia restrict its applications.					
36583973	1	28	theme	due	222:224	arg1	strategy					156:163	an emerging antibacterial strategy	130:163	an emerging antibacterial strategy	130:163	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	28	theme	due	222:224	arg1	attention					212:220	increasing attention	201:220	increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance	201:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	8	29	theme	photothermal	1625:1636	arg1	disinfection					1638:1649	mild-temperature photothermal disinfection	1608:1649	mild-temperature photothermal disinfection	1608:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	5	30	theme	photothermal	1000:1011	arg1	agent					1013:1017	a photothermal agent and color indicator	998:1037	agent	1013:1017	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	2	31	theme	normal	408:413	arg1	tissue					415:420	normal tissue	408:420	normal tissue	408:420	However, the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia restrict its applications.					
36583973	6	32	theme	bacterial	1243:1251	arg1	metabolism					1253:1262	bacterial metabolism	1243:1262	bacterial metabolism	1243:1262	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	3	33	theme	composite	493:501	arg1	hydrogel					503:510	a composite hydrogel	491:510	a composite hydrogel with the ability of on-demand generation of photothermal components	491:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	6	34	theme	corresponding	1276:1288	arg1	changes					1296:1302	corresponding color changes	1276:1302	corresponding color changes	1276:1302	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	2	35	theme	unavoidable	317:327	arg1	shielding					329:337	the unavoidable shielding	313:337	the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia	313:443	However, the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia restrict its applications.					
36583973	8	36	from	breakthrough	1541:1552	arg1	generation					1567:1576	on-demand generation	1557:1576	on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection	1557:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	7	37	theme	mild	1489:1492	arg1	temperature					1494:1504	a mild temperature	1487:1504	a mild temperature of ∼41 °C	1487:1514	Meanwhile, under the combined treatment of heating/I2/Zn2+, the composite hydrogel can completely kill Escherichia coli and Staphylococcus aureus at a mild temperature of ∼41 °C.					
36583973	0	38	theme	On-Demand	26:34	arg1	Generation					36:45	On-Demand Generation	26:45	On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection	26:124	When Iodine Meets Starch: On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection.					
36583973	5	39	theme	color	1023:1027	arg1	indicator					1029:1037	a photothermal agent and color indicator	998:1037	indicator	1029:1037	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	6	40	theme	microenvironment	1216:1231	arg1	acidification					1195:1207	the acidification	1191:1207	the acidification of the microenvironment caused by bacterial metabolism	1191:1262	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	3	41	with	hydrogel	503:510	arg1	ability					521:527	the ability	517:527	the ability of on-demand generation of photothermal components	517:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	8	42	theme	hydrogels	1594:1602	arg1	generation					1567:1576	on-demand generation	1557:1576	on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection	1557:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	7	43	theme	°C	1513:1514	arg1	temperature					1494:1504	a mild temperature	1487:1504	a mild temperature of ∼41 °C	1487:1514	Meanwhile, under the combined treatment of heating/I2/Zn2+, the composite hydrogel can completely kill Escherichia coli and Staphylococcus aureus at a mild temperature of ∼41 °C.					
36583973	5	44	theme	iodine	924:929	arg1	functions					911:919	the triple functions	900:919	the triple functions	900:919	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	5	44	theme	iodine	924:929	arg1	disinfectant					950:961	a disinfectant	948:961	a disinfectant	948:961	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	1	45	theme	high	247:250	arg1	efficacy					252:259	high efficacy	247:259	high efficacy	247:259	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	8	46	theme	mild-temperature	1608:1623	arg1	disinfection					1638:1649	mild-temperature photothermal disinfection	1608:1649	mild-temperature photothermal disinfection	1608:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	6	47	theme	antibacterial	1117:1129	arg1	experiments					1131:1141	In vitro antibacterial experiments	1108:1141	In vitro antibacterial experiments	1108:1141	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	8	48	theme	photothermal	1581:1592	arg1	hydrogels					1594:1602	photothermal hydrogels	1581:1602	photothermal hydrogels for mild-temperature photothermal disinfection	1581:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	6	49	theme	color	1290:1294	arg1	changes					1296:1302	corresponding color changes	1276:1302	corresponding color changes	1276:1302	In vitro antibacterial experiments show that the composite hydrogel can respond to the acidification of the microenvironment caused by bacterial metabolism and produce corresponding color changes, realizing naked-eye observation.					
36583973	7	50	theme	combined	1359:1366	arg1	treatment					1368:1376	the combined treatment	1355:1376	the combined treatment of heating/I2/Zn2+	1355:1395	Meanwhile, under the combined treatment of heating/I2/Zn2+, the composite hydrogel can completely kill Escherichia coli and Staphylococcus aureus at a mild temperature of ∼41 °C.					
36583973	1	51	theme	emerging	133:140	arg1	strategy					156:163	an emerging antibacterial strategy	130:163	an emerging antibacterial strategy	130:163	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	51	theme	emerging	133:140	arg1	attention					212:220	increasing attention	201:220	increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance	201:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	3	52	theme	elegantly	630:638	arg1	tuning					640:645	elegantly tuning	630:645	elegantly tuning	630:645	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	5	53	theme	photothermal-chemotherapy	1049:1073	arg1	disinfection					1084:1095	photothermal-chemotherapy combined disinfection	1049:1095	photothermal-chemotherapy combined disinfection on demand	1049:1105	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	3	54	dep	hydrogel	503:510	arg1	release					663:669	release	663:669	release	663:669	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	3	54	dep	hydrogel	503:510	arg1	binding					651:657	binding	651:657	binding	651:657	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	1	55	theme	antibacterial	142:154	arg1	strategy					156:163	an emerging antibacterial strategy	130:163	an emerging antibacterial strategy	130:163	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	55	theme	antibacterial	142:154	arg1	attention					212:220	increasing attention	201:220	increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance	201:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	56	theme	efficacy	252:259	arg1	advantages					233:242	its advantages	229:242	its advantages of high efficacy, wide pertinence, and non-drug resistance	229:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	7	57	theme	composite	1402:1410	arg1	hydrogel					1412:1419	the composite hydrogel	1398:1419	the composite hydrogel	1398:1419	Meanwhile, under the combined treatment of heating/I2/Zn2+, the composite hydrogel can completely kill Escherichia coli and Staphylococcus aureus at a mild temperature of ∼41 °C.					
36583973	3	58	theme	starch	685:690	arg1	release					663:669	release	663:669	release	663:669	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	3	58	theme	starch	685:690	arg1	binding					651:657	binding	651:657	binding	651:657	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	3	59	theme	photothermal	556:567	arg1	components					569:578	photothermal components	556:578	photothermal components	556:578	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	2	60	theme	photothermal	357:368	arg1	components					370:379	photothermal components	357:379	photothermal components	357:379	However, the unavoidable shielding of observation by photothermal components and the possible damage to normal tissue caused by hyperthermia restrict its applications.					
36583973	0	61	theme	Hydrogels	63:71	arg1	Generation					36:45	On-Demand Generation	26:45	On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection	26:124	When Iodine Meets Starch: On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection.					
36583973	4	62	theme	composite	697:705	arg1	hydrogel					707:714	The composite hydrogel	693:714	The composite hydrogel	693:714	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	8	63	theme	on-demand	1557:1565	arg1	generation					1567:1576	on-demand generation	1557:1576	on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection	1557:1649	This study represents a breakthrough in on-demand generation of photothermal hydrogels for mild-temperature photothermal disinfection.					
36583973	5	64	theme	triple	904:909	arg1	functions					911:919	the triple functions	900:919	the triple functions	900:919	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	5	64	theme	triple	904:909	arg1	disinfectant					950:961	a disinfectant	948:961	a disinfectant	948:961	Through a convenient pH response, the composite hydrogel leverages the triple functions of iodine, which serves as a disinfectant and reacts with starch to generate a photothermal agent and color indicator, allowing photothermal-chemotherapy combined disinfection on demand.					
36583973	4	65	theme	pH-responsive	756:768	arg1	NPs					791:793	NPs	791:793	NPs	791:793	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	4	65	theme	pH-responsive	756:768	arg1	nanoparticles					776:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles	740:788	iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix	740:830	The composite hydrogel is obtained by blending iodine-adsorbed pH-responsive ZIF-8 nanoparticles (NPs) with a starch-based hydrogel matrix.					
36583973	1	66	theme	wide	262:265	arg1	pertinence					267:276	wide pertinence	262:276	wide pertinence	262:276	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	0	67	theme	Photothermal	50:61	arg1	Hydrogels					63:71	Photothermal Hydrogels	50:71	Photothermal Hydrogels	50:71	When Iodine Meets Starch: On-Demand Generation of Photothermal Hydrogels for Mild-Temperature Photothermal-Chemo Disinfection.					
36583973	3	68	theme	iodine	674:679	arg1	release					663:669	release	663:669	release	663:669	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	3	68	theme	iodine	674:679	arg1	binding					651:657	binding	651:657	binding	651:657	Herein, we propose a composite hydrogel with the ability of on-demand generation of photothermal components and mild-temperature photothermal disinfection by elegantly tuning the binding and release of iodine and starch.					
36583973	7	69	theme	heating/I2/Zn2+	1381:1395	arg1	treatment					1368:1376	the combined treatment	1355:1376	the combined treatment of heating/I2/Zn2+	1355:1395	Meanwhile, under the combined treatment of heating/I2/Zn2+, the composite hydrogel can completely kill Escherichia coli and Staphylococcus aureus at a mild temperature of ∼41 °C.					
36583973	1	70	theme	photothermal	166:177	arg1	disinfection					179:190	photothermal disinfection	166:190	photothermal disinfection	166:190	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
36583973	1	71	theme	pertinence	267:276	arg1	advantages					233:242	its advantages	229:242	its advantages of high efficacy, wide pertinence, and non-drug resistance	229:301	As an emerging antibacterial strategy, photothermal disinfection attracts increasing attention due to its advantages of high efficacy, wide pertinence, and non-drug resistance.					
35628396	0	0	theme	Promising	83:91	arg1	Healing					99:105	Promising Wound Healing	83:105	Promising Wound Healing Nanomaterials	83:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	5	1	theme	special	989:995	arg1	emphasis					997:1004	a special emphasis	987:1004	a special emphasis on the role played by the incorporated metal oxide	987:1055	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	4	2	theme	thrombine	873:881	arg1	time					883:886	thrombine time	873:886	thrombine time	873:886	Biological activity of the nano-composites films was also studied including their hemolytic activity, methemoglobin, prothrombin, and thrombine time.					
35628396	2	3	theme	transparent	543:553	arg1	shaping					521:527	their shaping	515:527	their shaping	515:527	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	3	theme	transparent	543:553	arg1	films					568:572	crake-free transparent and flexible films	532:572	crake-free transparent and flexible films	532:572	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	3	theme	transparent	543:553	arg1	growth					437:442	growth	437:442	growth	437:442	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	3	theme	transparent	543:553	arg1	entrapment					422:431	entrapment	422:431	entrapment	422:431	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	6	4	theme	films	1172:1176	arg1	inside					1158:1163	the ceramic phase embedded inside	1131:1163	the ceramic phase embedded inside of the films	1131:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	0	5	theme	Healing	99:105	arg1	Nanomaterials					107:119	Promising Wound Healing Nanomaterials	83:119	Promising Wound Healing Nanomaterials	83:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	5	6	from	emphasis	997:1004	arg1	role					1013:1016	the role	1009:1016	the role played by the incorporated metal oxide	1009:1055	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	1	7	theme	evaporation-induced	315:333	arg1	assembly					335:342	evaporation-induced assembly	315:342	evaporation-induced assembly	315:342	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	0	8	theme	Wound	93:97	arg1	Healing					99:105	Promising Wound Healing	83:105	Promising Wound Healing Nanomaterials	83:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	2	9	dep	entrapment	422:431	arg1	the					418:420	the	418:420	the	418:420	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	10	theme	disclosed	349:357	arg1	straightforward					371:385	straightforward	371:385	straightforward	371:385	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	10	theme	disclosed	349:357	arg1	approach					359:366	The disclosed approach	345:366	The disclosed approach	345:366	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	6	11	theme	ceramic	1135:1141	arg1	inside					1158:1163	the ceramic phase embedded inside	1131:1163	the ceramic phase embedded inside of the films	1131:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	1	12	dep	Micrometer-thicker	122:139	arg1	responsive					155:164	responsive	155:164	responsive	155:164	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	2	13	theme	set	449:451	arg1	shaping					521:527	their shaping	515:527	their shaping	515:527	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	13	theme	set	449:451	arg1	films					568:572	crake-free transparent and flexible films	532:572	crake-free transparent and flexible films	532:572	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	13	theme	set	449:451	arg1	growth					437:442	growth	437:442	growth	437:442	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	13	theme	set	449:451	arg1	entrapment					422:431	entrapment	422:431	entrapment	422:431	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	14	theme	glassy-like	456:466	arg1	oxide					474:478	glassy-like metal oxide	456:478	glassy-like metal oxide within the network of alginate	456:509	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	0	15	theme	Glassy-like	0:10	arg1	Oxide					18:22	Glassy-like Metal Oxide	0:22	Glassy-like Metal Oxide Particles	0:32	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	0	16	theme	Metal	12:16	arg1	Oxide					18:22	Glassy-like Metal Oxide	0:22	Glassy-like Metal Oxide Particles	0:32	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	6	17	theme	healing	1236:1242	arg1	purposes					1244:1251	wound healing purposes	1230:1251	wound healing purposes	1230:1251	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	6	18	theme	inside	1158:1163	arg1	response					1119:1126	the crucial biological response	1096:1126	the crucial biological response of the ceramic phase embedded inside of the films	1096:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	1	19	theme	alginate-metal	214:227	arg1	solution					248:255	alginate-metal alkoxide colloidal solution	214:255	alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly	214:342	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	2	20	theme	alginate	502:509	arg1	network					491:497	the network	487:497	the network of alginate	487:509	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	6	21	theme	comparative	1063:1073	arg1	study					1075:1079	This comparative study	1058:1079	This comparative study	1058:1079	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	6	22	theme	wound	1230:1234	arg1	healing					1236:1242	wound healing	1230:1242	wound healing purposes	1230:1251	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	1	23	theme	alkoxide	229:236	arg1	solution					248:255	alginate-metal alkoxide colloidal solution	214:255	alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly	214:342	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	5	24	theme	films	907:911	arg1	effect					893:898	The effect	889:898	The effect of the films on fibroblasts and keratinocytes of human skin	889:958	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	3	25	theme	alginate	624:631	arg1	solubilization					633:646	alginate solubilization	624:646	alginate solubilization	624:646	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	1	26	theme	colloidal	238:246	arg1	solution					248:255	alginate-metal alkoxide colloidal solution	214:255	alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly	214:342	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	0	27	theme	Oxide	18:22	arg1	Particles					24:32	Glassy-like Metal Oxide Particles	0:32	Glassy-like Metal Oxide Particles	0:32	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	5	28	theme	metal	1045:1049	arg1	oxide					1051:1055	the incorporated metal oxide	1028:1055	the incorporated metal oxide	1028:1055	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	6	29	theme	titanium	1184:1191	arg1	promising					1216:1224	promising	1216:1224	promising	1216:1224	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	6	29	theme	titanium	1184:1191	arg1	dioxide					1193:1199	titanium dioxide	1184:1199	titanium dioxide	1184:1199	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	2	30	theme	crake-free	532:541	arg1	shaping					521:527	their shaping	515:527	their shaping	515:527	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	30	theme	crake-free	532:541	arg1	films					568:572	crake-free transparent and flexible films	532:572	crake-free transparent and flexible films	532:572	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	30	theme	crake-free	532:541	arg1	growth					437:442	growth	437:442	growth	437:442	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	30	theme	crake-free	532:541	arg1	entrapment					422:431	entrapment	422:431	entrapment	422:431	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	4	31	theme	nano-composites	766:780	arg1	films					782:786	the nano-composites films	762:786	the nano-composites films	762:786	Biological activity of the nano-composites films was also studied including their hemolytic activity, methemoglobin, prothrombin, and thrombine time.					
35628396	4	32	theme	Biological	739:748	arg1	activity					750:757	Biological activity	739:757	Biological activity of the nano-composites films	739:786	Biological activity of the nano-composites films was also studied including their hemolytic activity, methemoglobin, prothrombin, and thrombine time.					
35628396	3	33	theme	metal	675:679	arg1	oxides					681:686	water-soluble metal oxides	661:686	water-soluble metal oxides wrapped in a biocompatible carbohydrate framework	661:736	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	6	34	theme	embedded	1149:1156	arg1	inside					1158:1163	the ceramic phase embedded inside	1131:1163	the ceramic phase embedded inside of the films	1131:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	2	35	theme	oxide	474:478	arg1	oxide					474:478	glassy-like metal oxide	456:478	glassy-like metal oxide within the network of alginate	456:509	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	35	theme	oxide	474:478	arg1	set					449:451	a set	447:451	a set of glassy-like metal oxide within the network of alginate	447:509	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	5	36	theme	skin	955:958	arg1	keratinocytes					932:944	keratinocytes	932:944	keratinocytes	932:944	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	5	36	theme	skin	955:958	arg1	fibroblasts					916:926	fibroblasts	916:926	fibroblasts	916:926	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	3	37	theme	carbohydrate	715:726	arg1	framework					728:736	a biocompatible carbohydrate framework	699:736	a biocompatible carbohydrate framework	699:736	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	2	38	theme	metal	468:472	arg1	oxide					474:478	glassy-like metal oxide	456:478	glassy-like metal oxide within the network of alginate	456:509	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	0	39	theme	Thicker	57:63	arg1	Films					74:78	Micrometer Thicker Alginate Films	46:78	Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials	46:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	2	40	theme	flexible	559:566	arg1	shaping					521:527	their shaping	515:527	their shaping	515:527	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	40	theme	flexible	559:566	arg1	films					568:572	crake-free transparent and flexible films	532:572	crake-free transparent and flexible films	532:572	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	40	theme	flexible	559:566	arg1	growth					437:442	growth	437:442	growth	437:442	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	2	40	theme	flexible	559:566	arg1	entrapment					422:431	entrapment	422:431	entrapment	422:431	The disclosed approach is straightforward and highly versatile, allowing the entrapment and growth of a set of glassy-like metal oxide within the network of alginate and their shaping as crake-free transparent and flexible films.					
35628396	1	41	theme	Micrometer-thicker	122:139	arg1	films					180:184	Micrometer-thicker, biologically responsive nanocomposite films	122:184	Micrometer-thicker, biologically responsive nanocomposite films	122:184	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	0	42	theme	Micrometer	46:55	arg1	Films					74:78	Micrometer Thicker Alginate Films	46:78	Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials	46:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	3	43	theme	water-soluble	661:673	arg1	oxides					681:686	water-soluble metal oxides	661:686	water-soluble metal oxides wrapped in a biocompatible carbohydrate framework	661:736	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	5	44	theme	incorporated	1032:1043	arg1	oxide					1051:1055	the incorporated metal oxide	1028:1055	the incorporated metal oxide	1028:1055	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	1	45	theme	sol-gel	269:275	arg1	chemistry					277:285	sol-gel chemistry	269:285	sol-gel chemistry	269:285	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	3	46	theme	aqueous	600:606	arg1	medium					608:613	aqueous medium	600:613	aqueous medium	600:613	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	3	47	theme	biocompatible	701:713	arg1	framework					728:736	a biocompatible carbohydrate framework	699:736	a biocompatible carbohydrate framework	699:736	Immersing these films in aqueous medium triggers alginate solubilization, and affords water-soluble metal oxides wrapped in a biocompatible carbohydrate framework.					
35628396	4	48	theme	hemolytic	821:829	arg1	activity					831:838	their hemolytic activity	815:838	their hemolytic activity	815:838	Biological activity of the nano-composites films was also studied including their hemolytic activity, methemoglobin, prothrombin, and thrombine time.					
35628396	6	49	theme	biological	1108:1117	arg1	response					1119:1126	the crucial biological response	1096:1126	the crucial biological response of the ceramic phase embedded inside of the films	1096:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	5	50	theme	human	949:953	arg1	skin					955:958	human skin	949:958	human skin	949:958	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	6	51	theme	phase	1143:1147	arg1	inside					1158:1163	the ceramic phase embedded inside	1131:1163	the ceramic phase embedded inside of the films	1131:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	1	52	theme	nanocomposite	166:178	arg1	films					180:184	Micrometer-thicker, biologically responsive nanocomposite films	122:184	Micrometer-thicker, biologically responsive nanocomposite films	122:184	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
35628396	6	53	theme	crucial	1100:1106	arg1	response					1119:1126	the crucial biological response	1096:1126	the crucial biological response of the ceramic phase embedded inside of the films	1096:1176	This comparative study sheds light on the crucial biological response of the ceramic phase embedded inside of the films, with titanium dioxide being the most promising for wound healing purposes.					
35628396	0	54	theme	Alginate	65:72	arg1	Films					74:78	Micrometer Thicker Alginate Films	46:78	Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials	46:119	Glassy-like Metal Oxide Particles Embedded on Micrometer Thicker Alginate Films as Promising Wound Healing Nanomaterials.					
35628396	5	55	from	effect	893:898	arg1	keratinocytes					932:944	keratinocytes	932:944	keratinocytes	932:944	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	5	55	from	effect	893:898	arg1	fibroblasts					916:926	fibroblasts	916:926	fibroblasts	916:926	The effect of the films on fibroblasts and keratinocytes of human skin was also investigated with a special emphasis on the role played by the incorporated metal oxide.					
35628396	4	56	theme	films	782:786	arg1	activity					750:757	Biological activity	739:757	Biological activity of the nano-composites films	739:786	Biological activity of the nano-composites films was also studied including their hemolytic activity, methemoglobin, prothrombin, and thrombine time.					
35628396	1	57	theme	solvent	291:297	arg1	removal					299:305	solvent removal	291:305	solvent removal through evaporation-induced assembly	291:342	Micrometer-thicker, biologically responsive nanocomposite films were prepared starting from alginate-metal alkoxide colloidal solution followed by sol-gel chemistry and solvent removal through evaporation-induced assembly.					
36076058	0	0	theme	gut	84:86	arg1	microbiome					88:97	the human gut microbiome	74:97	the human gut microbiome	74:97	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	5	1	theme	high-quality	795:806	arg1	MAGs					838:841	MAGs	838:841	MAGs	838:841	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	5	1	theme	high-quality	795:806	arg1	genomes					829:835	509 high-quality metagenome-assembled genomes	791:835	509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families	791:903	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	4	2	theme	controlled	720:729	arg1	gut					737:739	a controlled model gut	718:739	a controlled model gut using hybrid metagenome assemblies	718:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	2	3	theme	host	350:353	arg1	health					355:360	host health	350:360	host health	350:360	This is a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes.					
36076058	0	4	theme	human	78:82	arg1	microbiome					88:97	the human gut microbiome	74:97	the human gut microbiome	74:97	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	6	5	theme	starch	962:967	arg1	modules					977:983	starch binding modules	962:983	starch binding modules	962:983	Bacterial species identified as carrying genes encoding starch binding modules increased in abundance in response to starches.					
36076058	7	6	theme	starch	1162:1167	arg1	substrates					1169:1178	starch substrates	1162:1178	starch substrates for future study	1162:1195	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	4	7	from	carbohydrates	701:713	arg1	gut					737:739	a controlled model gut	718:739	a controlled model gut using hybrid metagenome assemblies	718:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	4	8	theme	species-level	595:607	arg1	variation					623:631	species-level compositional variation	595:631	species-level compositional variation	595:631	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	7	9	theme	future	1184:1189	arg1	study					1191:1195	future study	1184:1195	future study	1184:1195	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	4	10	theme	hybrid	747:752	arg1	assemblies					765:774	hybrid metagenome assemblies	747:774	hybrid metagenome assemblies	747:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	6	11	theme	binding	969:975	arg1	modules					977:983	starch binding modules	962:983	starch binding modules	962:983	Bacterial species identified as carrying genes encoding starch binding modules increased in abundance in response to starches.					
36076058	4	12	theme	single	642:647	arg1	microbiome					649:658	a single microbiome	640:658	a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies	640:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	2	13	theme	other	383:387	arg1	microbes					389:396	other microbes	383:396	other microbes	383:396	This is a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes.					
36076058	2	14	theme	symbiotic	253:261	arg1	This					243:246	This	243:246	This	243:246	This is a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes.					
36076058	2	14	theme	symbiotic	253:261	arg1	relationship					263:274	a symbiotic relationship	251:274	a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes	251:396	This is a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes.					
36076058	3	15	theme	carbohydrate	420:431	arg1	structure					433:441	carbohydrate structure	420:441	carbohydrate structure	420:441	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	0	16	theme	metagenome	7:16	arg1	assemblies					18:27	Hybrid metagenome assemblies	0:27	Hybrid metagenome assemblies	0:27	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	5	17	theme	metagenome-assembled	808:827	arg1	MAGs					838:841	MAGs	838:841	MAGs	838:841	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	5	17	theme	metagenome-assembled	808:827	arg1	genomes					829:835	509 high-quality metagenome-assembled genomes	791:835	509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families	791:903	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	7	18	theme	species	1113:1119	arg1	identification					1076:1089	identification	1076:1089	identification of several uncultured species with the functional potential	1076:1149	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	4	19	theme	distinct	692:699	arg1	carbohydrates					701:713	six structurally distinct carbohydrates	675:713	six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies	675:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	0	20	theme	Hybrid	0:5	arg1	assemblies					18:27	Hybrid metagenome assemblies	0:27	Hybrid metagenome assemblies	0:27	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	4	21	theme	metagenome	754:763	arg1	assemblies					765:774	hybrid metagenome assemblies	747:774	hybrid metagenome assemblies	747:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	1	22	theme	large	185:189	arg1	intestine					191:199	the large intestine	181:199	the large intestine	181:199	Complex carbohydrates that escape small intestinal digestion, are broken down in the large intestine by enzymes encoded by the gut microbiome.					
36076058	7	23	theme	functional	1130:1139	arg1	potential					1141:1149	the functional potential	1126:1149	the functional potential	1126:1149	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	1	24	theme	Complex	100:106	arg1	carbohydrates					108:120	Complex carbohydrates	100:120	Complex carbohydrates	100:120	Complex carbohydrates that escape small intestinal digestion, are broken down in the large intestine by enzymes encoded by the gut microbiome.					
36076058	5	25	theme	bacterial	861:869	arg1	classes					871:877	ten bacterial classes	857:877	ten bacterial classes	857:877	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	4	26	from	microbiome	649:658	arg1	response					663:670	response	663:670	response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies	663:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	3	27	theme	microbiota	456:465	arg1	composition					477:487	microbiota community composition	456:487	microbiota community composition	456:487	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	6	28	theme	Bacterial	906:914	arg1	species					916:922	Bacterial species	906:922	Bacterial species identified as carrying genes encoding starch binding modules	906:983	Bacterial species identified as carrying genes encoding starch binding modules increased in abundance in response to starches.					
36076058	7	29	with	species	1113:1119	arg1	potential					1141:1149	the functional potential	1126:1149	the functional potential	1126:1149	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	3	30	theme	structure	433:441	arg1	role					412:415	the role	408:415	the role	408:415	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	0	31	theme	carbohydrate	34:45	arg1	structure					47:55	carbohydrate structure	34:55	carbohydrate structure with function	34:69	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	5	32	theme	bacterial	886:894	arg1	families					896:903	28 bacterial families	883:903	28 bacterial families	883:903	We identified 509 high-quality metagenome-assembled genomes (MAGs) belonging to ten bacterial classes and 28 bacterial families.					
36076058	7	33	theme	uncultured	1102:1111	arg1	species					1113:1119	several uncultured species	1094:1119	several uncultured species with the functional potential	1094:1149	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	4	34	theme	compositional	609:621	arg1	variation					623:631	species-level compositional variation	595:631	species-level compositional variation	595:631	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	3	35	theme	community	467:475	arg1	composition					477:487	microbiota community composition	456:487	microbiota community composition	456:487	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	7	36	theme	metagenomics	1051:1062	arg1	use					1037:1039	The use	1033:1039	The use of hybrid metagenomics	1033:1062	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	4	37	theme	model	731:735	arg1	gut					737:739	a controlled model gut	718:739	a controlled model gut using hybrid metagenome assemblies	718:774	In this study we evaluate species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates in a controlled model gut using hybrid metagenome assemblies.					
36076058	1	38	theme	small	134:138	arg1	digestion					151:159	small intestinal digestion	134:159	small intestinal digestion	134:159	Complex carbohydrates that escape small intestinal digestion, are broken down in the large intestine by enzymes encoded by the gut microbiome.					
36076058	7	39	theme	several	1094:1100	arg1	species					1113:1119	several uncultured species	1094:1119	several uncultured species with the functional potential	1094:1149	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	1	40	theme	intestinal	140:149	arg1	digestion					151:159	small intestinal digestion	134:159	small intestinal digestion	134:159	Complex carbohydrates that escape small intestinal digestion, are broken down in the large intestine by enzymes encoded by the gut microbiome.					
36076058	2	41	theme	metabolic	316:324	arg1	products					326:333	metabolic products	316:333	metabolic products that influence host health and are exploited by other microbes	316:396	This is a symbiotic relationship between microbes and host, resulting in metabolic products that influence host health and are exploited by other microbes.					
36076058	7	42	theme	hybrid	1044:1049	arg1	metagenomics					1051:1062	hybrid metagenomics	1044:1062	hybrid metagenomics	1044:1062	The use of hybrid metagenomics has allowed identification of several uncultured species with the functional potential to degrade starch substrates for future study.					
36076058	3	43	theme	carbohydrate-degrading	511:532	arg1	microbes					534:541	carbohydrate-degrading microbes	511:541	carbohydrate-degrading microbes	511:541	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	1	44	theme	gut	227:229	arg1	microbiome					231:240	the gut microbiome	223:240	the gut microbiome	223:240	Complex carbohydrates that escape small intestinal digestion, are broken down in the large intestine by enzymes encoded by the gut microbiome.					
36076058	0	45	with	structure	47:55	arg1	function					62:69	function	62:69	function	62:69	Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome.					
36076058	3	46	theme	microbes	534:541	arg1	composition					477:487	microbiota community composition	456:487	microbiota community composition	456:487	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36076058	3	46	theme	microbes	534:541	arg1	succession					497:506	the succession	493:506	the succession of carbohydrate-degrading microbes	493:541	However, the role of carbohydrate structure in directing microbiota community composition and the succession of carbohydrate-degrading microbes, is not fully understood.					
36192964	9	0	theme	reversible	1326:1335	arg1	response					1340:1347	a sensitive and reversible pH response	1310:1347	a sensitive and reversible pH response	1310:1347	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	5	1	theme	cationic	663:670	arg1	biopolymer					672:681	A cationic biopolymer	661:681	A cationic biopolymer (chitosan)	661:692	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	1	theme	cationic	663:670	arg1	material					720:727	a scaffolding material	706:727	a scaffolding material	706:727	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	1	theme	cationic	663:670	arg1	chitosan					684:691	chitosan	684:691	chitosan	684:691	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	7	2	dep	Fourier	846:852	arg1	transform					854:862	transform	854:862	transform infrared spectroscopy and scanning electron microscopy analyses	854:926	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	3	3	theme	packaging	502:510	arg1	materials					512:520	environmentally friendly pH-sensitive packaging materials	464:520	environmentally friendly pH-sensitive packaging materials	464:520	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	9	4	theme	products	1430:1437	arg1	freshness					1401:1409	the freshness	1397:1409	the freshness of pork and shrimp products	1397:1437	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	8	5	theme	film	1180:1183	arg1	hydrophobicity					1132:1145	hydrophobicity	1132:1145	hydrophobicity	1132:1145	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	8	5	theme	film	1180:1183	arg1	properties					1162:1171	mechanical properties	1151:1171	mechanical properties	1151:1171	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	4	6	theme	Natural	523:529	arg1	anthocyanins					554:565	anthocyanins	554:565	anthocyanins	554:565	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	4	6	theme	Natural	523:529	arg1	pigments					544:551	Natural pH-sensitive pigments	523:551	Natural pH-sensitive pigments (anthocyanins)	523:566	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	6	7	theme	solvent	822:828	arg1	method					838:843	a simple solvent casting method	813:843	a simple solvent casting method	813:843	Composite film (LCNC-PCCE-chitosan) was produced using a simple solvent casting method.					
36192964	1	8	theme	packaging	157:165	arg1	materials					167:175	petroleum-based food packaging materials	136:175	petroleum-based food packaging materials	136:175	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	7	9	theme	scanning	890:897	arg1	microscopy					908:917	scanning electron microscopy	890:917	scanning electron microscopy	890:917	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	9	10	attach	presence	1251:1258	arg2	anthocyanins					1263:1274	anthocyanins	1263:1274	anthocyanins	1263:1274	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	9	10	attach	presence	1251:1258	arg1	PCCE					1283:1286	the PCCE	1279:1286	the PCCE	1279:1286	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	7	11	dep	spectroscopy	873:884	arg1	analyses					919:926	analyses	919:926	analyses	919:926	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	0	12	from	Development	0:10	arg1	meat					98:101	meat	98:101	meat	98:101	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	9	13	used	used	1370:1373	arg2	response					1340:1347	a sensitive and reversible pH response	1310:1347	a sensitive and reversible pH response	1310:1347	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	6	14	theme	simple	815:820	arg1	method					838:843	a simple solvent casting method	813:843	a simple solvent casting method	813:843	Composite film (LCNC-PCCE-chitosan) was produced using a simple solvent casting method.					
36192964	7	15	theme	electron	899:906	arg1	microscopy					908:917	scanning electron microscopy	890:917	scanning electron microscopy	890:917	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	8	16	theme	antioxidant	1198:1208	arg1	activity					1210:1217	antioxidant activity	1198:1217	antioxidant activity	1198:1217	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	3	17	theme	agricultural	368:379	arg1	extract					411:417	purple corncob extract	396:417	purple corncob extract	396:417	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	17	theme	agricultural	368:379	arg1	material					444:451	a raw material	438:451	a raw material	438:451	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	17	theme	agricultural	368:379	arg1	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	1	18	theme	food	152:155	arg1	materials					167:175	petroleum-based food packaging materials	136:175	petroleum-based food packaging materials	136:175	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	5	19	theme	film	745:748	arg1	matrix					750:755	the film matrix	741:755	the film matrix	741:755	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	20	used	used	698:701	arg2	chitosan					684:691	chitosan	684:691	chitosan	684:691	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	20	used	used	698:701	arg2	biopolymer					672:681	A cationic biopolymer	661:681	A cationic biopolymer (chitosan)	661:692	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	20	used	used	698:701	arg2	material					720:727	a scaffolding material	706:727	a scaffolding material	706:727	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	1	21	theme	materials	167:175	arg1	use					129:131	The use	125:131	The use of petroleum-based food packaging materials	125:175	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	3	22	dep	extract	411:417	arg1	PCCE					420:423	PCCE	420:423	PCCE	420:423	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	23	used	used	430:433	arg2	extract					411:417	purple corncob extract	396:417	purple corncob extract	396:417	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	23	used	used	430:433	arg2	material					444:451	a raw material	438:451	a raw material	438:451	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	23	used	used	430:433	arg2	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	9	24	theme	sensitive	1312:1320	arg1	response					1340:1347	a sensitive and reversible pH response	1310:1347	a sensitive and reversible pH response	1310:1347	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	2	25	theme	alternative	327:337	arg1	materials					339:347	smart and sustainable alternative materials	305:347	smart and sustainable alternative materials	305:347	Consequently, there is a great interest in developing smart and sustainable alternative materials.					
36192964	7	26	theme	infrared	864:871	arg1	spectroscopy					873:884	infrared spectroscopy	864:884	infrared spectroscopy	864:884	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	3	27	theme	purple	396:401	arg1	extract					411:417	purple corncob extract	396:417	purple corncob extract	396:417	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	27	theme	purple	396:401	arg1	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	0	28	from	application	83:93	arg1	meat					98:101	meat	98:101	meat	98:101	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	9	29	theme	anthocyanins	1263:1274	arg1	presence					1251:1258	The presence	1247:1258	The presence of anthocyanins in the PCCE	1247:1286	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	2	30	theme	sustainable	315:325	arg1	materials					339:347	smart and sustainable alternative materials	305:347	smart and sustainable alternative materials	305:347	Consequently, there is a great interest in developing smart and sustainable alternative materials.					
36192964	9	31	with	endowed	1288:1294	arg1	response					1340:1347	a sensitive and reversible pH response	1310:1347	a sensitive and reversible pH response	1310:1347	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	1	32	theme	environmental	188:200	arg1	damage					202:207	environmental damage	188:207	environmental damage	188:207	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	3	33	theme	waste	381:385	arg1	extract					411:417	purple corncob extract	396:417	purple corncob extract	396:417	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	33	theme	waste	381:385	arg1	material					444:451	a raw material	438:451	a raw material	438:451	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	33	theme	waste	381:385	arg1	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	8	34	theme	LCNC	1114:1117	arg1	addition					1102:1109	The addition	1098:1109	The addition of LCNC	1098:1117	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	0	35	theme	pH-responsive	15:27	arg1	materials					41:49	pH-responsive active film materials	15:49	pH-responsive active film materials based on purple corncob	15:73	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	4	36	theme	cellulose	590:598	arg1	LCNC					614:617	LCNC	614:617	LCNC	614:617	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	4	36	theme	cellulose	590:598	arg1	nanocrystals					600:611	lignin-containing cellulose nanocrystals	572:611	lignin-containing cellulose nanocrystals (LCNC)	572:618	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	5	37	theme	scaffolding	708:718	arg1	biopolymer					672:681	A cationic biopolymer	661:681	A cationic biopolymer (chitosan)	661:692	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	5	37	theme	scaffolding	708:718	arg1	material					720:727	a scaffolding material	706:727	a scaffolding material	706:727	A cationic biopolymer (chitosan) was used as a scaffolding material to assemble the film matrix.					
36192964	2	38	theme	smart	305:309	arg1	materials					339:347	smart and sustainable alternative materials	305:347	smart and sustainable alternative materials	305:347	Consequently, there is a great interest in developing smart and sustainable alternative materials.					
36192964	4	39	theme	purple	644:649	arg1	corncobs					651:658	the purple corncobs	640:658	the purple corncobs	640:658	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	0	40	theme	materials	41:49	arg1	Development					0:10	Development	0:10	Development of pH-responsive active film materials based on purple corncob	0:73	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	0	40	theme	materials	41:49	arg1	application					83:93	its application	79:93	its application in meat	79:101	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	4	41	theme	lignin-containing	572:588	arg1	LCNC					614:617	LCNC	614:617	LCNC	614:617	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	4	41	theme	lignin-containing	572:588	arg1	nanocrystals					600:611	lignin-containing cellulose nanocrystals	572:611	lignin-containing cellulose nanocrystals (LCNC)	572:618	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	0	42	theme	film	36:39	arg1	materials					41:49	pH-responsive active film materials	15:49	pH-responsive active film materials based on purple corncob	15:73	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	0	43	theme	active	29:34	arg1	materials					41:49	pH-responsive active film materials	15:49	pH-responsive active film materials based on purple corncob	15:73	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	1	44	theme	greenhouse	224:233	arg1	production					239:248	greenhouse gas production	224:248	greenhouse gas production	224:248	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	3	45	theme	corncob	403:409	arg1	extract					411:417	purple corncob extract	396:417	purple corncob extract	396:417	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	45	theme	corncob	403:409	arg1	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	4	46	theme	pH-sensitive	531:542	arg1	anthocyanins					554:565	anthocyanins	554:565	anthocyanins	554:565	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	4	46	theme	pH-sensitive	531:542	arg1	pigments					544:551	Natural pH-sensitive pigments	523:551	Natural pH-sensitive pigments (anthocyanins)	523:566	Natural pH-sensitive pigments (anthocyanins) and lignin-containing cellulose nanocrystals (LCNC) were extracted from the purple corncobs.					
36192964	7	47	theme	electrostatic	1070:1082	arg1	interactions					1084:1095	electrostatic interactions	1070:1095	electrostatic interactions	1070:1095	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	6	48	theme	Composite	758:766	arg1	LCNC-PCCE-chitosan					774:791	LCNC-PCCE-chitosan	774:791	LCNC-PCCE-chitosan	774:791	Composite film (LCNC-PCCE-chitosan) was produced using a simple solvent casting method.					
36192964	6	48	theme	Composite	758:766	arg1	film					768:771	Composite film	758:771	Composite film (LCNC-PCCE-chitosan)	758:792	Composite film (LCNC-PCCE-chitosan) was produced using a simple solvent casting method.					
36192964	3	49	theme	pH-sensitive	489:500	arg1	materials					512:520	environmentally friendly pH-sensitive packaging materials	464:520	environmentally friendly pH-sensitive packaging materials	464:520	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	7	50	theme	hydrogen	1049:1056	arg1	bonding					1058:1064	hydrogen bonding	1049:1064	hydrogen bonding	1049:1064	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	7	51	theme	chitosan	989:996	arg1	matrix					998:1003	the chitosan matrix	985:1003	the chitosan matrix	985:1003	Fourier transform infrared spectroscopy and scanning electron microscopy analyses showed that the PCCE and LCNC were well dispersed within the chitosan matrix and they interacted with the matrix through hydrogen bonding and electrostatic interactions.					
36192964	9	52	from	presence	1251:1258	arg1	PCCE					1283:1286	the PCCE	1279:1286	the PCCE	1279:1286	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	1	53	theme	gas	235:237	arg1	production					239:248	greenhouse gas production	224:248	greenhouse gas production	224:248	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	2	54	theme	great	276:280	arg1	interest					282:289	a great interest	274:289	a great interest in developing smart and sustainable alternative materials	274:347	Consequently, there is a great interest in developing smart and sustainable alternative materials.					
36192964	8	55	theme	UV-blocking	1223:1233	arg1	properties					1235:1244	UV-blocking properties	1223:1244	UV-blocking properties	1223:1244	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	9	56	theme	pork	1414:1417	arg1	products					1430:1437	pork and shrimp products	1414:1437	pork and shrimp products	1414:1437	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	9	57	from	changes	1386:1392	arg1	freshness					1401:1409	the freshness	1397:1409	the freshness of pork and shrimp products	1397:1437	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	3	58	theme	raw	440:442	arg1	material					444:451	a raw material	438:451	a raw material	438:451	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	3	58	theme	raw	440:442	arg1	product					387:393	an agricultural waste product	365:393	an agricultural waste product (purple corncob extract, PCCE)	365:424	In this study, an agricultural waste product (purple corncob extract, PCCE) was used as a raw material to prepare environmentally friendly pH-sensitive packaging materials.					
36192964	6	59	theme	casting	830:836	arg1	method					838:843	a simple solvent casting method	813:843	a simple solvent casting method	813:843	Composite film (LCNC-PCCE-chitosan) was produced using a simple solvent casting method.					
36192964	0	60	theme	purple	60:65	arg1	corncob					67:73	purple corncob	60:73	purple corncob	60:73	Development of pH-responsive active film materials based on purple corncob and its application in meat freshness monitoring.					
36192964	9	61	theme	pH	1337:1338	arg1	response					1340:1347	a sensitive and reversible pH response	1310:1347	a sensitive and reversible pH response	1310:1347	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36192964	8	62	dep	hydrophobicity	1132:1145	arg1	the					1128:1130	the	1128:1130	the	1128:1130	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	1	63	theme	petroleum-based	136:150	arg1	materials					167:175	petroleum-based food packaging materials	136:175	petroleum-based food packaging materials	136:175	The use of petroleum-based food packaging materials is causing environmental damage and increasing greenhouse gas production.					
36192964	8	64	theme	mechanical	1151:1160	arg1	properties					1162:1171	mechanical properties	1151:1171	mechanical properties	1151:1171	The addition of LCNC improved the hydrophobicity and mechanical properties of the film and imparted antioxidant activity and UV-blocking properties.					
36192964	9	65	theme	shrimp	1423:1428	arg1	products					1430:1437	pork and shrimp products	1414:1437	pork and shrimp products	1414:1437	The presence of anthocyanins in the PCCE endowed the film with a sensitive and reversible pH response, which could be well used to monitor changes in the freshness of pork and shrimp products.					
36346262	12	0	theme	%	1920:1920	arg1	%					1930:1930	0 wt% to 20 wt%	1916:1930	0 wt% to 20 wt%	1916:1930	The results indicate that increasing MgO content from 0 wt% to 20 wt% enhances each structure's compressive strength and elastic modulus.					
36346262	9	1	used	used	1459:1462	arg2	properties					1443:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	6	2	theme	biological	964:973	arg1	studies					975:981	biological studies	964:981	biological studies	964:981	The results of biological studies indicate that the apatite layer covered the majority of composite scaffold's surface and sealed the pores' surface.					
36346262	3	3	from	concentrations	461:474	arg1	alginate/MgO					441:452	alginate/MgO	441:452	alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	441:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	10	4	theme	mechanical	1664:1673	arg1	properties					1675:1684	the mechanical properties	1660:1684	the mechanical properties of scaffolds	1660:1697	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	7	5	theme	%	1272:1272	arg1	nanoparticles					1278:1290	20 wt% MgO nanoparticles	1267:1290	20 wt% MgO nanoparticles	1267:1290	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	10	6	theme	element	1619:1625	arg1	simulation					1627:1636	finite element simulation	1612:1636	finite element simulation	1612:1636	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	13	7	theme	biological	2028:2037	arg1	findings					2039:2046	the biological findings	2024:2046	the biological findings	2024:2046	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	12	8	theme	MgO	1899:1901	arg1	content					1903:1909	MgO content	1899:1909	MgO content	1899:1909	The results indicate that increasing MgO content from 0 wt% to 20 wt% enhances each structure's compressive strength and elastic modulus.					
36346262	11	9	theme	type	1829:1832	arg1	>σIWP					1855:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	3	10	theme	5 wt	486:489	arg1	%					490:490	5 wt%	486:490	5 wt%	486:490	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	10	11	used	used	1643:1646	arg2	experiment					1597:1606	experiment	1597:1606	experiment	1597:1606	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	10	11	used	used	1643:1646	arg2	simulation					1627:1636	finite element simulation	1612:1636	finite element simulation	1612:1636	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	13	12	theme	Perovskite	2090:2099	arg1	architecture					2113:2124	Perovskite type 1 (P1) architecture	2090:2124	Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2090:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	4	13	theme	fabricated	578:587	arg1	scaffolds					589:597	fabricated scaffolds	578:597	fabricated scaffolds	578:597	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	2	14	theme	scaffold	321:328	arg1	models					330:335	Three unique scaffold models	308:335	Three unique scaffold models	308:335	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	1	15	theme	L-lactic	202:209	arg1	PLA					217:219	PLA	217:219	PLA	217:219	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	1	15	theme	L-lactic	202:209	arg1	acid					211:214	Poly L-lactic acid	197:214	3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO	186:255	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	9	16	theme	material	1545:1552	arg1	properties					1554:1563	the material properties	1541:1563	the material properties	1541:1563	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	4	17	theme	phase	543:547	arg1	study					549:553	morphological and phase study	525:553	study	549:553	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	5	18	theme	antibacterial	834:846	arg1	activity					848:855	antibacterial activity	834:855	antibacterial activity	834:855	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	3	19	theme	%	498:498	arg1	concentrations					461:474	the concentrations	457:474	the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	457:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	0	20	theme	bone	140:143	arg1	regeneration					152:163	bone tissue regeneration	140:163	bone tissue regeneration	140:163	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	3	21	theme	20 wt	513:517	arg1	%					518:518	20 wt%	513:518	20 wt%	513:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	7	22	dep	100	1226:1228	arg1	MPA					1253:1255	130 MPA	1249:1255	100 (pure Alginate) to 130 MPA	1226:1255	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	7	22	dep	100	1226:1228	arg1	to					1246:1247	to	1246:1247	to	1246:1247	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	4	23	theme	Field	625:629	arg1	FESEM					670:674	FESEM	670:674	FESEM	670:674	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	23	theme	Field	625:629	arg1	Microscope					658:667	a Field Emission Scanning Electron Microscope	623:667	a Field Emission Scanning Electron Microscope (FESEM)	623:675	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	5	24	theme	body	931:934	arg1	SBF					943:945	SBF	943:945	SBF	943:945	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	5	24	theme	body	931:934	arg1	fluid					936:940	the simulated body fluid	917:940	the simulated body fluid (SBF)	917:946	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	11	25	theme	1>σPerovskite	1834:1846	arg1	>σIWP					1855:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	13	26	theme	Alginate/	2138:2146	arg1	MgO					2155:2157	Alginate/ 20 wt% MgO	2138:2157	Alginate/ 20 wt% MgO	2138:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	4	27	theme	Scanning	640:647	arg1	FESEM					670:674	FESEM	670:674	FESEM	670:674	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	27	theme	Scanning	640:647	arg1	Microscope					658:667	a Field Emission Scanning Electron Microscope	623:667	a Field Emission Scanning Electron Microscope (FESEM)	623:675	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	6	28	theme	surface	1060:1066	arg1	majority					1027:1034	the majority	1023:1034	the majority of composite scaffold's surface	1023:1066	The results of biological studies indicate that the apatite layer covered the majority of composite scaffold's surface and sealed the pores' surface.					
36346262	13	29	theme	%	2153:2153	arg1	MgO					2155:2157	Alginate/ 20 wt% MgO	2138:2157	Alginate/ 20 wt% MgO	2138:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	12	30	theme	compressive	1958:1968	arg1	strength					1970:1977	each structure's compressive strength	1941:1977	each structure's compressive strength	1941:1977	The results indicate that increasing MgO content from 0 wt% to 20 wt% enhances each structure's compressive strength and elastic modulus.					
36346262	0	31	theme	printed	62:68	arg1	acid					84:87	antibacterial 3D printed Poly L-lactic acid	45:87	antibacterial 3D printed Poly L-lactic acid	45:87	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	10	32	theme	scaffolds	1689:1697	arg1	properties					1675:1684	the mechanical properties	1660:1684	the mechanical properties of scaffolds	1660:1697	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	0	33	theme	L-lactic	75:82	arg1	acid					84:87	antibacterial 3D printed Poly L-lactic acid	45:87	antibacterial 3D printed Poly L-lactic acid	45:87	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	5	34	theme	scaffolds	797:805	arg1	characteristics					778:792	the biological characteristics	763:792	the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival	763:874	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	5	35	theme	cell	862:865	arg1	survival					867:874	cell survival	862:874	cell survival	862:874	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	4	36	theme	dispersive	685:694	arg1	EDS					710:712	EDS	710:712	EDS	710:712	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	36	theme	dispersive	685:694	arg1	spectroscopy					696:707	energy dispersive spectroscopy	678:707	energy dispersive spectroscopy (EDS)	678:713	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	0	37	dep	scaffolds	89:97	arg1	coated					99:104	coated	99:104	scaffolds coated with alginate/magnesium oxide for bone tissue regeneration	89:163	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	9	38	from	studies	1482:1488	arg1	scaffolds					1497:1505	the scaffolds	1493:1505	the scaffolds	1493:1505	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	7	39	theme	elastic	1196:1202	arg1	modulus					1204:1210	the elastic modulus	1192:1210	the elastic modulus	1192:1210	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	11	40	theme	compressive	1764:1774	arg1	strength					1776:1783	the compressive strength	1760:1783	the compressive strength of structures	1760:1797	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	1	41	theme	different	277:285	arg1	topologies					296:305	three different cellular topologies	271:305	three different cellular topologies	271:305	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	9	42	theme	material	1434:1441	arg1	properties					1443:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	11	43	theme	order	1811:1815	arg1	>σIWP					1855:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	0	44	theme	finite	16:21	arg1	simulation					31:40	finite element simulation	16:40	finite element simulation	16:40	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	13	45	theme	P1	2109:2110	arg1	architecture					2113:2124	Perovskite type 1 (P1) architecture	2090:2124	Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2090:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	4	46	theme	diffraction	726:736	arg1	analysis					744:751	X-ray diffraction (XRD) analysis	720:751	X-ray diffraction (XRD) analysis	720:751	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	2	47	theme	Perovskite	354:363	arg1	type					365:368	Perovskite type 1	354:370	Perovskite type 1 (P1)	354:375	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	2	47	theme	Perovskite	354:363	arg1	P1					373:374	P1	373:374	P1	373:374	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	0	48	theme	antibacterial	45:57	arg1	acid					84:87	antibacterial 3D printed Poly L-lactic acid	45:87	antibacterial 3D printed Poly L-lactic acid	45:87	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	9	49	theme	additional	1471:1480	arg1	studies					1482:1488	the additional studies	1467:1488	the additional studies on the scaffolds	1467:1505	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	6	50	theme	apatite	1001:1007	arg1	layer					1009:1013	the apatite layer	997:1013	the apatite layer	997:1013	The results of biological studies indicate that the apatite layer covered the majority of composite scaffold's surface and sealed the pores' surface.					
36346262	6	51	theme	composite	1039:1047	arg1	surface					1060:1066	composite scaffold's surface	1039:1066	composite scaffold's surface	1039:1066	The results of biological studies indicate that the apatite layer covered the majority of composite scaffold's surface and sealed the pores' surface.					
36346262	13	52	theme	research	2200:2207	arg1	candidate					2209:2217	the final research candidate	2190:2217	the final research candidate	2190:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	52	theme	research	2200:2207	arg1	response					2172:2179	the best response	2163:2179	the best response which is the final research candidate	2163:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	3	53	theme	0 wt	479:482	arg1	%					483:483	0 wt%	479:483	0 wt%	479:483	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	1	54	theme	3D-printed	186:195	arg1	scaffolds					222:230	3D-printed Poly L-lactic acid (PLA) scaffolds	186:230	3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO	186:255	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	13	55	theme	simulation	2052:2061	arg1	results					2063:2069	simulation results	2052:2069	simulation results	2052:2069	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	6	56	theme	studies	975:981	arg1	results					953:959	The results	949:959	The results of biological studies	949:981	The results of biological studies indicate that the apatite layer covered the majority of composite scaffold's surface and sealed the pores' surface.					
36346262	13	57	with	scaffold	2076:2083	arg1	architecture					2113:2124	Perovskite type 1 (P1) architecture	2090:2124	Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2090:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	3	58	theme	%	490:490	arg1	concentrations					461:474	the concentrations	457:474	the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	457:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	9	59	theme	best	1519:1522	arg1	candidate					1524:1532	the best candidate	1515:1532	the best candidate due to the material properties and architectures	1515:1581	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	7	60	theme	MgO	1274:1276	arg1	nanoparticles					1278:1290	20 wt% MgO nanoparticles	1267:1290	20 wt% MgO nanoparticles	1267:1290	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	10	61	theme	finite	1612:1617	arg1	simulation					1627:1636	finite element simulation	1612:1636	finite element simulation	1612:1636	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	9	62	theme	due	1534:1536	arg1	candidate					1524:1532	the best candidate	1515:1532	the best candidate due to the material properties and architectures	1515:1581	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	7	63	theme	20 wt	1267:1271	arg1	nanoparticles					1278:1290	20 wt% MgO nanoparticles	1267:1290	20 wt% MgO nanoparticles	1267:1290	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	1	64	theme	Poly	197:200	arg1	PLA					217:219	PLA	217:219	PLA	217:219	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	1	64	theme	Poly	197:200	arg1	acid					211:214	Poly L-lactic acid	197:214	3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO	186:255	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	5	65	theme	simulated	921:929	arg1	SBF					943:945	SBF	943:945	SBF	943:945	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	5	65	theme	simulated	921:929	arg1	fluid					936:940	the simulated body fluid	917:940	the simulated body fluid (SBF)	917:946	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	2	66	theme	unique	314:319	arg1	models					330:335	Three unique scaffold models	308:335	Three unique scaffold models	308:335	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	1	67	theme	acid	211:214	arg1	scaffolds					222:230	3D-printed Poly L-lactic acid (PLA) scaffolds	186:230	3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO	186:255	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	3	68	theme	15 wt	501:505	arg1	%					506:506	15 wt%	501:506	15 wt%	501:506	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	0	69	theme	tissue	145:150	arg1	regeneration					152:163	bone tissue regeneration	140:163	bone tissue regeneration	140:163	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	11	70	theme	type	1848:1851	arg1	>σIWP					1855:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	8	71	theme	presented	1297:1305	arg1	findings					1307:1314	The presented findings	1293:1314	The presented findings	1293:1314	The presented findings were compared to the results obtained by the experimental procedure and revealed satisfactory agreement.					
36346262	12	72	theme	elastic	1983:1989	arg1	modulus					1991:1997	elastic modulus	1983:1997	elastic modulus	1983:1997	The results indicate that increasing MgO content from 0 wt% to 20 wt% enhances each structure's compressive strength and elastic modulus.					
36346262	3	73	theme	%	506:506	arg1	concentrations					461:474	the concentrations	457:474	the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	457:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	7	74	theme	pure	1231:1234	arg1	100					1226:1228	100	1226:1228	100	1226:1228	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	7	74	theme	pure	1231:1234	arg1	Alginate					1236:1243	pure Alginate	1231:1243	pure Alginate	1231:1243	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	10	75	theme	compressive	1709:1719	arg1	deformation					1721:1731	the compressive deformation	1705:1731	the compressive deformation	1705:1731	Furthermore, experiment and finite element simulation were used to evaluate the mechanical properties of scaffolds under the compressive deformation.					
36346262	13	76	theme	20 wt	2148:2152	arg1	MgO					2155:2157	Alginate/ 20 wt% MgO	2138:2157	Alginate/ 20 wt% MgO	2138:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	3	77	theme	10 wt	493:497	arg1	%					498:498	10 wt%	493:498	10 wt%	493:498	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	4	78	theme	Emission	631:638	arg1	FESEM					670:674	FESEM	670:674	FESEM	670:674	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	78	theme	Emission	631:638	arg1	Microscope					658:667	a Field Emission Scanning Electron Microscope	623:667	a Field Emission Scanning Electron Microscope (FESEM)	623:675	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	0	79	theme	Poly	70:73	arg1	acid					84:87	antibacterial 3D printed Poly L-lactic acid	45:87	antibacterial 3D printed Poly L-lactic acid	45:87	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	3	80	theme	%	518:518	arg1	concentrations					461:474	the concentrations	457:474	the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	457:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	5	81	theme	biological	767:776	arg1	characteristics					778:792	the biological characteristics	763:792	the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival	763:874	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	4	82	theme	scaffolds	589:597	arg1	microstructure					560:573	the microstructure	556:573	the microstructure of fabricated scaffolds	556:597	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	0	83	theme	acid	84:87	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	0	83	theme	acid	84:87	arg1	simulation					31:40	finite element simulation	16:40	finite element simulation	16:40	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	1	84	dep	different	277:285	arg1	cellular					287:294	cellular	287:294	cellular	287:294	This study proposes 3D-printed Poly L-lactic acid (PLA) scaffolds coated with alginate/MgO, and includes three different cellular topologies.					
36346262	8	85	theme	experimental	1361:1372	arg1	procedure					1374:1382	the experimental procedure	1357:1382	the experimental procedure	1357:1382	The presented findings were compared to the results obtained by the experimental procedure and revealed satisfactory agreement.					
36346262	12	86	dep	%	1930:1930	arg1	to					1922:1923	to	1922:1923	to	1922:1923	The results indicate that increasing MgO content from 0 wt% to 20 wt% enhances each structure's compressive strength and elastic modulus.					
36346262	0	87	theme	alginate/magnesium	111:128	arg1	oxide					130:134	alginate/magnesium oxide	111:134	alginate/magnesium oxide for bone tissue regeneration	111:163	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	4	88	theme	energy	678:683	arg1	EDS					710:712	EDS	710:712	EDS	710:712	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	88	theme	energy	678:683	arg1	spectroscopy					696:707	energy dispersive spectroscopy	678:707	energy dispersive spectroscopy (EDS)	678:713	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	2	89	theme	Perovskite	378:387	arg1	type					389:392	Perovskite type 2	378:394	Perovskite type 2 (P2)	378:399	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	2	89	theme	Perovskite	378:387	arg1	P2					397:398	P2	397:398	P2	397:398	Three unique scaffold models were considered: Perovskite type 1 (P1), Perovskite type 2 (P2), and IWP.					
36346262	9	90	theme	RVE-achieved	1421:1432	arg1	properties					1443:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties	1421:1452	RVE-achieved material properties were used in the additional studies on the scaffolds to find the best candidate due to the material properties and architectures.					
36346262	8	91	theme	satisfactory	1397:1408	arg1	agreement					1410:1418	satisfactory agreement	1397:1418	satisfactory agreement	1397:1418	The presented findings were compared to the results obtained by the experimental procedure and revealed satisfactory agreement.					
36346262	4	92	theme	Electron	649:656	arg1	FESEM					670:674	FESEM	670:674	FESEM	670:674	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	92	theme	Electron	649:656	arg1	Microscope					658:667	a Field Emission Scanning Electron Microscope	623:667	a Field Emission Scanning Electron Microscope (FESEM)	623:675	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	0	93	theme	element	23:29	arg1	simulation					31:40	finite element simulation	16:40	finite element simulation	16:40	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	13	94	theme	type	2101:2104	arg1	architecture					2113:2124	Perovskite type 1 (P1) architecture	2090:2124	Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2090:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	11	95	theme	σPerovskite	1817:1827	arg1	>σIWP					1855:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	the order σPerovskite type 1>σPerovskite type 2 >σIWP	1807:1859	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	5	96	theme	soaking	906:912	arg1	21 days					895:901	21 days	895:901	21 days of soaking	895:912	Besides, the biological characteristics of scaffolds, such as biocompatibility, antibacterial activity, and cell survival were studied after 21 days of soaking in the simulated body fluid (SBF).					
36346262	0	97	theme	3D	59:60	arg1	acid					84:87	antibacterial 3D printed Poly L-lactic acid	45:87	antibacterial 3D printed Poly L-lactic acid	45:87	Fabrication and finite element simulation of antibacterial 3D printed Poly L-lactic acid scaffolds coated with alginate/magnesium oxide for bone tissue regeneration.					
36346262	13	98	theme	PLA	2072:2074	arg1	scaffold					2076:2083	PLA scaffold	2072:2083	PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2072:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	4	99	theme	X-ray	720:724	arg1	XRD					739:741	XRD	739:741	XRD	739:741	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	4	99	theme	X-ray	720:724	arg1	diffraction					726:736	X-ray diffraction	720:736	X-ray diffraction (XRD) analysis	720:751	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	13	100	contain	had	2159:2161	arg1	scaffold					2076:2083	PLA scaffold	2072:2083	PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO	2072:2157	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	100	contain	had	2159:2161	arg2	response					2172:2179	the best response	2163:2179	the best response which is the final research candidate	2163:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	100	contain	had	2159:2161	arg2	candidate					2209:2217	the final research candidate	2190:2217	the final research candidate	2190:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	101	theme	final	2194:2198	arg1	candidate					2209:2217	the final research candidate	2190:2217	the final research candidate	2190:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	101	theme	final	2194:2198	arg1	response					2172:2179	the best response	2163:2179	the best response which is the final research candidate	2163:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	7	102	theme	RVEs	1139:1142	arg1	properties					1112:1121	The material properties	1099:1121	The material properties of Alginate/MgO RVEs	1099:1142	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36346262	13	103	theme	best	2167:2170	arg1	candidate					2209:2217	the final research candidate	2190:2217	the final research candidate	2190:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	13	103	theme	best	2167:2170	arg1	response					2172:2179	the best response	2163:2179	the best response which is the final research candidate	2163:2217	In conclusion, based on the biological findings and simulation results, PLA scaffold with Perovskite type 1 (P1) architecture coated with Alginate/ 20 wt% MgO had the best response which is the final research candidate.					
36346262	11	104	theme	structures	1788:1797	arg1	strength					1776:1783	the compressive strength	1760:1783	the compressive strength of structures	1760:1797	According to the results, the compressive strength of structures follows the order σPerovskite type 1>σPerovskite type 2 >σIWP.					
36346262	4	105	theme	morphological	525:537	arg1	study					549:553	morphological and phase study	525:553	study	549:553	For morphological and phase study, the microstructure of fabricated scaffolds was characterized using a Field Emission Scanning Electron Microscope (FESEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis.					
36346262	3	106	theme	%	483:483	arg1	concentrations					461:474	the concentrations	457:474	the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%	457:518	Each scaffold was coated with alginate/MgO at the concentrations of 0 wt%, 5 wt%, 10 wt%, 15 wt%, and 20 wt%.					
36346262	7	107	theme	material	1103:1110	arg1	properties					1112:1121	The material properties	1099:1121	The material properties of Alginate/MgO RVEs	1099:1142	The material properties of Alginate/MgO RVEs were evaluated under PBC, and it described that the elastic modulus enhanced from 100 (pure Alginate) to 130 MPA by adding 20 wt% MgO nanoparticles.					
36876799	7	0	theme	phosphatase	1149:1159	arg1	formation					1127:1135	the formation	1123:1135	the formation of alkaline phosphatase and calcium nodules	1123:1179	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	3	1	theme	chitosan	496:503	arg1	Di					522:523	Di	522:523	Di	522:523	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	1	theme	chitosan	496:503	arg1	/diatomite					510:519	alginate (AG)/quaternized chitosan (Qch)/diatomite	470:519	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	8	2	theme	tooth	1274:1278	arg1	extraction					1280:1289	tooth extraction	1274:1289	tooth extraction	1274:1289	The designed bio-multifunctional sponges display great potential for trauma treatment after tooth extraction.					
36876799	0	3	theme	dry	107:109	arg1	socket					111:116	dry socket	107:116	dry socket	107:116	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	6	4	theme	prepared	877:884	arg1	sponges					886:892	The prepared sponges	873:892	The prepared sponges	873:892	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	1	5	theme	bone	251:254	arg1	resorption					256:265	the dry socket and bone resorption	232:265	resorption	256:265	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
36876799	8	6	theme	designed	1186:1193	arg1	sponges					1215:1221	The designed bio-multifunctional sponges	1182:1221	The designed bio-multifunctional sponges	1182:1221	The designed bio-multifunctional sponges display great potential for trauma treatment after tooth extraction.					
36876799	7	7	theme	alkaline	1140:1147	arg1	phosphatase					1149:1159	alkaline phosphatase	1140:1159	alkaline phosphatase	1140:1159	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	7	8	contain	have	1032:1035	arg1	sponges					1024:1030	the developed sponges	1010:1030	the developed sponges	1010:1030	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	7	8	contain	have	1032:1035	arg2	cytocompatibility					1047:1063	favorable cytocompatibility	1037:1063	favorable cytocompatibility	1037:1063	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	5	9	theme	porous	824:829	arg1	structure					831:839	a highly interconnected and hierarchical porous structure	783:839	a highly interconnected and hierarchical porous structure at the macro/micro/nano levels	783:870	The sponge shows a highly interconnected and hierarchical porous structure at the macro/micro/nano levels.					
36876799	5	10	theme	interconnected	792:805	arg1	structure					831:839	a highly interconnected and hierarchical porous structure	783:839	a highly interconnected and hierarchical porous structure at the macro/micro/nano levels	783:870	The sponge shows a highly interconnected and hierarchical porous structure at the macro/micro/nano levels.					
36876799	3	11	theme	alginate	470:477	arg1	Di					522:523	Di	522:523	Di	522:523	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	11	theme	alginate	470:477	arg1	/diatomite					510:519	alginate (AG)/quaternized chitosan (Qch)/diatomite	470:519	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	12	theme	/diatomite	510:519	arg1	sponges					526:532	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	2	13	theme	osteogenic	387:396	arg1	performances					398:409	antimicrobial, hemostatic, and osteogenic performances	356:409	antimicrobial, hemostatic, and osteogenic performances	356:409	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	0	14	theme	socket	111:116	arg1	prevention					93:102	the prevention	89:102	the prevention of dry socket	89:116	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	0	15	theme	Root-shaped	0:10	arg1	sponges					35:41	Root-shaped antibacterial alginate sponges	0:41	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.	0:117	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	1	16	theme	blood	183:187	arg1	clots					189:193	blood clots	183:193	blood clots	183:193	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
36876799	0	17	theme	antibacterial	12:24	arg1	sponges					35:41	Root-shaped antibacterial alginate sponges	0:41	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.	0:117	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	1	18	theme	clots	189:193	arg1	loss					175:178	loss	175:178	loss of blood clots	175:193	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
36876799	2	19	theme	clinical	439:446	arg1	applications					448:459	clinical applications	439:459	clinical applications	439:459	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	4	20	theme	root	704:707	arg1	shape					685:689	the shape	681:689	the shape of the tooth root, which could be well integrated into the alveolar fossa	681:763	The composite sponges are facilely made into the shape of the tooth root, which could be well integrated into the alveolar fossa.					
36876799	7	21	dep	in	966:967	arg1	vitro					969:973	vitro	969:973	vitro	969:973	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	2	22	theme	hemostatic	371:380	arg1	performances					398:409	antimicrobial, hemostatic, and osteogenic performances	356:409	antimicrobial, hemostatic, and osteogenic performances	356:409	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	8	23	theme	trauma	1251:1256	arg1	treatment					1258:1266	trauma treatment	1251:1266	trauma treatment	1251:1266	The designed bio-multifunctional sponges display great potential for trauma treatment after tooth extraction.					
36876799	5	24	from	levels	865:870	arg1	structure					831:839	a highly interconnected and hierarchical porous structure	783:839	a highly interconnected and hierarchical porous structure at the macro/micro/nano levels	783:870	The sponge shows a highly interconnected and hierarchical porous structure at the macro/micro/nano levels.					
36876799	2	25	theme	dry	424:426	arg1	sockets					428:434	dry sockets	424:434	dry sockets	424:434	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	0	26	theme	alginate	26:33	arg1	sponges					35:41	Root-shaped antibacterial alginate sponges	0:41	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.	0:117	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	1	27	theme	bacterial	200:208	arg1	infection					210:218	bacterial infection	200:218	bacterial infection	200:218	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
36876799	0	28	theme	enhanced	48:55	arg1	hemostasis					57:66	hemostasis	57:66	hemostasis	57:66	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	3	29	theme	/quaternized	483:494	arg1	Di					522:523	Di	522:523	Di	522:523	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	29	theme	/quaternized	483:494	arg1	/diatomite					510:519	alginate (AG)/quaternized chitosan (Qch)/diatomite	470:519	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	6	30	contain	possess	899:905	arg1	sponges					886:892	The prepared sponges	873:892	The prepared sponges	873:892	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	6	30	contain	possess	899:905	arg2	abilities					945:953	enhanced hemostatic and antibacterial abilities	907:953	enhanced hemostatic and antibacterial abilities	907:953	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	4	31	theme	composite	640:648	arg1	sponges					650:656	The composite sponges	636:656	The composite sponges	636:656	The composite sponges are facilely made into the shape of the tooth root, which could be well integrated into the alveolar fossa.					
36876799	6	32	theme	antibacterial	931:943	arg1	abilities					945:953	enhanced hemostatic and antibacterial abilities	907:953	enhanced hemostatic and antibacterial abilities	907:953	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	3	33	theme	Ca2+	581:584	arg1	cross-linking					586:598	Ca2+ cross-linking	581:598	Ca2+ cross-linking	581:598	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	0	34	with	sponges	35:41	arg1	osteogenesis					72:83	osteogenesis	72:83	osteogenesis	72:83	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	0	34	with	sponges	35:41	arg1	hemostasis					57:66	hemostasis	57:66	hemostasis	57:66	Root-shaped antibacterial alginate sponges with enhanced hemostasis and osteogenesis for the prevention of dry socket.					
36876799	5	35	theme	hierarchical	811:822	arg1	structure					831:839	a highly interconnected and hierarchical porous structure	783:839	a highly interconnected and hierarchical porous structure at the macro/micro/nano levels	783:870	The sponge shows a highly interconnected and hierarchical porous structure at the macro/micro/nano levels.					
36876799	7	36	theme	calcium	1165:1171	arg1	nodules					1173:1179	calcium nodules	1165:1179	calcium nodules	1165:1179	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	5	37	theme	macro/micro/nano	848:863	arg1	levels					865:870	the macro/micro/nano levels	844:870	the macro/micro/nano levels	844:870	The sponge shows a highly interconnected and hierarchical porous structure at the macro/micro/nano levels.					
36876799	7	38	theme	favorable	1037:1045	arg1	cytocompatibility					1047:1063	favorable cytocompatibility	1037:1063	favorable cytocompatibility	1037:1063	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	3	39	theme	lyophilization	612:625	arg1	methods					627:633	lyophilization methods	612:633	lyophilization methods	612:633	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	40	theme	electrostatic	554:566	arg1	interaction					568:578	electrostatic interaction	554:578	electrostatic interaction	554:578	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	7	41	theme	developed	1014:1022	arg1	sponges					1024:1030	the developed sponges	1010:1030	the developed sponges	1010:1030	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	1	42	theme	Tooth	119:123	arg1	extraction					125:134	Tooth extraction	119:134	Tooth extraction	119:134	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
36876799	7	43	theme	nodules	1173:1179	arg1	formation					1127:1135	the formation	1123:1135	the formation of alkaline phosphatase and calcium nodules	1123:1179	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	6	44	theme	hemostatic	916:925	arg1	abilities					945:953	enhanced hemostatic and antibacterial abilities	907:953	enhanced hemostatic and antibacterial abilities	907:953	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	2	45	theme	bio-multifunctional	310:328	arg1	scaffold					330:337	a bio-multifunctional scaffold	308:337	a bio-multifunctional scaffold	308:337	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	6	46	theme	enhanced	907:914	arg1	abilities					945:953	enhanced hemostatic and antibacterial abilities	907:953	enhanced hemostatic and antibacterial abilities	907:953	The prepared sponges also possess enhanced hemostatic and antibacterial abilities.					
36876799	4	47	theme	alveolar	750:757	arg1	fossa					759:763	the alveolar fossa	746:763	the alveolar fossa	746:763	The composite sponges are facilely made into the shape of the tooth root, which could be well integrated into the alveolar fossa.					
36876799	4	48	theme	tooth	698:702	arg1	root					704:707	the tooth root	694:707	the tooth root	694:707	The composite sponges are facilely made into the shape of the tooth root, which could be well integrated into the alveolar fossa.					
36876799	8	49	theme	bio-multifunctional	1195:1213	arg1	sponges					1215:1221	The designed bio-multifunctional sponges	1182:1221	The designed bio-multifunctional sponges	1182:1221	The designed bio-multifunctional sponges display great potential for trauma treatment after tooth extraction.					
36876799	8	50	theme	great	1231:1235	arg1	potential					1237:1245	great potential	1231:1245	great potential for trauma treatment after tooth extraction	1231:1289	The designed bio-multifunctional sponges display great potential for trauma treatment after tooth extraction.					
36876799	7	51	theme	cellular	975:982	arg1	assessment					984:993	in vitro cellular assessment	966:993	in vitro cellular assessment	966:993	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	3	52	theme	AG	480:481	arg1	Di					522:523	Di	522:523	Di	522:523	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	52	theme	AG	480:481	arg1	/diatomite					510:519	alginate (AG)/quaternized chitosan (Qch)/diatomite	470:519	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	53	theme	Qch	506:508	arg1	Di					522:523	Di	522:523	Di	522:523	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	3	53	theme	Qch	506:508	arg1	/diatomite					510:519	alginate (AG)/quaternized chitosan (Qch)/diatomite	470:519	alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges	470:532	Herein, alginate (AG)/quaternized chitosan (Qch)/diatomite (Di) sponges were fabricated via electrostatic interaction, Ca2+ cross-linking, as well as lyophilization methods.					
36876799	7	54	theme	in	966:967	arg1	assessment					984:993	in vitro cellular assessment	966:993	in vitro cellular assessment	966:993	Moreover, in vitro cellular assessment indicates that the developed sponges have favorable cytocompatibility and significantly facilitate osteogenesis by upregulating the formation of alkaline phosphatase and calcium nodules.					
36876799	2	55	theme	antimicrobial	356:368	arg1	performances					398:409	antimicrobial, hemostatic, and osteogenic performances	356:409	antimicrobial, hemostatic, and osteogenic performances	356:409	Thus, it is highly attractive to design a bio-multifunctional scaffold with outstanding antimicrobial, hemostatic, and osteogenic performances for avoiding dry sockets in clinical applications.					
36876799	1	56	theme	dry	236:238	arg1	socket					240:245	the dry socket and bone resorption	232:265	socket	240:245	Tooth extraction commonly causes uncontrolled bleeding, loss of blood clots, and bacterial infection, leading to the dry socket and bone resorption.					
35554807	3	0	theme	mean	600:603	arg1	size					610:613	a mean pore size	598:613	a mean pore size of around 3.8 nm	598:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	5	1	theme	BPA	1016:1018	arg1	concentrations					1020:1033	BPA concentrations	1016:1033	BPA concentrations in the range 25-100 mg/L	1016:1058	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	2	theme	Isotherm	782:789	arg1	model					791:795	Isotherm model	782:795	Isotherm model	782:795	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	3	from	C-AC	847:850	arg1	model					791:795	Isotherm model	782:795	Isotherm model	782:795	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	3	from	C-AC	847:850	arg1	study					810:814	kinetics study	801:814	kinetics study	801:814	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	1	4	theme	cellulose	218:226	arg1	efficiency					143:152	the efficiency	139:152	the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C)	139:233	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	5	5	from	concentrations	1020:1033	arg1	range					1042:1046	the range	1038:1046	the range 25-100 mg/L	1038:1058	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	3	6	with	volume	647:652	arg1	size					610:613	a mean pore size	598:613	a mean pore size of around 3.8 nm	598:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	2	7	theme	Low-cost	286:293	arg1	shells					328:333	Low-cost, renewable, and non-toxic shrimp shells	286:333	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose	286:354	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	5	8	theme	isotherm	932:939	arg1	model					941:945	the Langmuir adsorption isotherm model	908:945	the Langmuir adsorption isotherm model	908:945	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	0	9	theme	shrimp	100:105	arg1	cellulose					113:121	shrimp shell@cellulose	100:121	shrimp shell@cellulose	100:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	5	10	theme	kinetic	996:1002	arg1	results					1004:1010	kinetic results	996:1010	kinetic results	996:1010	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	11	from	model	791:795	arg1	C-AC					847:850	SS@C-AC	844:850	SS@C-AC	844:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	12	theme	BPA	837:839	arg1	adsorption					823:832	the adsorption	819:832	the adsorption of BPA on SS@C-AC	819:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	1	13	theme	SS	229:230	arg1	C					232:232	SS@C	229:232	SS@C	229:232	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	1	13	theme	SS	229:230	arg1	cellulose					218:226	cellulose	218:226	cellulose (SS@C)	218:233	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	5	14	with	agreement	893:901	arg1	model					941:945	the Langmuir adsorption isotherm model	908:945	the Langmuir adsorption isotherm model	908:945	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	15	theme	SS	844:845	arg1	C-AC					847:850	SS@C-AC	844:850	SS@C-AC	844:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	3	16	theme	SS	461:462	arg1	composite					491:499	a porous composite	482:499	a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	482:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	16	theme	SS	461:462	arg1	samples					469:475	SS@C-AC samples	461:475	SS@C-AC samples	461:475	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	17	with	area	574:577	arg1	size					610:613	a mean pore size	598:613	a mean pore size of around 3.8 nm	598:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	1	18	theme	@	231:231	arg1	C					232:232	SS@C	229:232	SS@C	229:232	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	1	18	theme	@	231:231	arg1	cellulose					218:226	cellulose	218:226	cellulose (SS@C)	218:233	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	0	19	theme	@	112:112	arg1	cellulose					113:121	shrimp shell@cellulose	100:121	shrimp shell@cellulose	100:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	6	20	theme	activation	1105:1114	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	20	theme	activation	1105:1114	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	20	theme	activation	1105:1114	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	5	21	theme	@	846:846	arg1	C-AC					847:850	SS@C-AC	844:850	SS@C-AC	844:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	1	22	theme	carbon	167:172	arg1	efficiency					143:152	the efficiency	139:152	the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C)	139:233	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	4	23	theme	values	718:723	arg1	influences					677:686	The influences	673:686	The influences of initial concentrations, pH values, and adsorption on BPA	673:746	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	0	24	theme	shell	107:111	arg1	cellulose					113:121	shrimp shell@cellulose	100:121	shrimp shell@cellulose	100:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	3	25	theme	pore	605:608	arg1	size					610:613	a mean pore size	598:613	a mean pore size of around 3.8 nm	598:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	2	26	dep	carbonized	361:370	arg1	followed					373:380	followed	373:380	followed by activation via CO2 and NaHCO3 to produce SS@C-AC	373:432	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	5	27	from	study	810:814	arg1	C-AC					847:850	SS@C-AC	844:850	SS@C-AC	844:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	2	28	theme	shrimp	321:326	arg1	shells					328:333	Low-cost, renewable, and non-toxic shrimp shells	286:333	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose	286:354	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	0	29	theme	efficient	7:15	arg1	adsorption					17:26	Highly efficient adsorption	0:26	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2	0:58	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	5	30	theme	25-100	1048:1053	arg1	mg/L					1055:1058	mg/L	1055:1058	mg/L	1055:1058	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	4	31	theme	adsorption	730:739	arg1	influences					677:686	The influences	673:686	The influences of initial concentrations, pH values, and adsorption on BPA	673:746	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	0	32	theme	carbon	70:75	arg1	composite					77:85	carbon composite	70:85	carbon composite derived from shrimp shell@cellulose	70:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	2	33	theme	non-toxic	311:319	arg1	shells					328:333	Low-cost, renewable, and non-toxic shrimp shells	286:333	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose	286:354	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	5	34	theme	mg/L	1055:1058	arg1	range					1042:1046	the range	1038:1046	the range 25-100 mg/L	1038:1058	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	35	theme	adsorption	823:832	arg1	model					791:795	Isotherm model	782:795	Isotherm model	782:795	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	5	35	theme	adsorption	823:832	arg1	study					810:814	kinetics study	801:814	kinetics study	801:814	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	6	36	theme	min	1127:1129	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	36	theme	min	1127:1129	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	36	theme	min	1127:1129	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	3	37	theme	mesoporous	636:645	arg1	volume					647:652	mesoporous volume	636:652	mesoporous volume of 1.83E-02 cm3/g	636:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	6	38	theme	BPA	1180:1182	arg1	removal					1184:1190	BPA removal	1180:1190	BPA removal of 81.78%	1180:1200	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	3	39	theme	@	463:463	arg1	composite					491:499	a porous composite	482:499	a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	482:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	39	theme	@	463:463	arg1	samples					469:475	SS@C-AC samples	461:475	SS@C-AC samples	461:475	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	6	40	theme	NaHCO3	1091:1096	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	40	theme	NaHCO3	1091:1096	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	40	theme	NaHCO3	1091:1096	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	5	41	dep	PFO	984:986	arg1	results					1004:1010	kinetic results	996:1010	kinetic results	996:1010	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	3	42	theme	specific	557:564	arg1	area					574:577	a relatively high specific surface area	539:577	a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm	539:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	42	theme	specific	557:564	arg1	m2/g					587:590	935.20 m2/g	580:590	935.20 m2/g	580:590	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	43	theme	C-AC	464:467	arg1	composite					491:499	a porous composite	482:499	a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	482:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	43	theme	C-AC	464:467	arg1	samples					469:475	SS@C-AC samples	461:475	SS@C-AC samples	461:475	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	0	44	theme	A	41:41	arg1	adsorption					17:26	Highly efficient adsorption	0:26	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2	0:58	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	3	45	theme	nm	629:630	arg1	size					610:613	a mean pore size	598:613	a mean pore size of around 3.8 nm	598:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	46	theme	surface	566:572	arg1	area					574:577	a relatively high specific surface area	539:577	a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm	539:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	46	theme	surface	566:572	arg1	m2/g					587:590	935.20 m2/g	580:590	935.20 m2/g	580:590	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	4	47	theme	concentrations	699:712	arg1	influences					677:686	The influences	673:686	The influences of initial concentrations, pH values, and adsorption on BPA	673:746	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	5	48	from	adsorption	823:832	arg1	C-AC					847:850	SS@C-AC	844:850	SS@C-AC	844:850	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	0	49	theme	Bisphenol	31:39	arg1	A					41:41	Bisphenol A	31:41	Bisphenol A using NaHCO3/CO2	31:58	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	4	50	theme	initial	691:697	arg1	concentrations					699:712	initial concentrations	691:712	initial concentrations	691:712	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	2	51	theme	@	428:428	arg1	C-AC					429:432	SS@C-AC	426:432	SS@C-AC	426:432	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	1	52	theme	Bisphenol	256:264	arg1	BPA					269:271	BPA	269:271	BPA	269:271	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	1	52	theme	Bisphenol	256:264	arg1	A					266:266	Bisphenol A	256:266	Bisphenol A (BPA) adsorption	256:283	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	6	53	theme	%	1200:1200	arg1	removal					1184:1190	BPA removal	1180:1190	BPA removal of 81.78%	1180:1200	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	3	54	theme	high	552:555	arg1	area					574:577	a relatively high specific surface area	539:577	a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm	539:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	54	theme	high	552:555	arg1	m2/g					587:590	935.20 m2/g	580:590	935.20 m2/g	580:590	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	4	55	theme	pH	715:716	arg1	values					718:723	pH values	715:723	pH values	715:723	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	6	56	from	800°C	1134:1138	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	56	from	800°C	1134:1138	arg1	min					1127:1129	90 min	1124:1129	90 min at 800°C	1124:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	56	from	800°C	1134:1138	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	56	from	800°C	1134:1138	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	1	57	theme	A	266:266	arg1	adsorption					274:283	Bisphenol A (BPA) adsorption	256:283	Bisphenol A (BPA) adsorption	256:283	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	3	58	theme	porous	484:489	arg1	composite					491:499	a porous composite	482:499	a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	482:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	58	theme	porous	484:489	arg1	samples					469:475	SS@C-AC samples	461:475	SS@C-AC samples	461:475	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	5	59	theme	kinetics	801:808	arg1	study					810:814	kinetics study	801:814	kinetics study	801:814	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	6	60	theme	impregnation	1065:1076	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	60	theme	impregnation	1065:1076	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	60	theme	impregnation	1065:1076	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	0	61	attach	derived	87:93	arg1	cellulose					113:121	shrimp shell@cellulose	100:121	shrimp shell@cellulose	100:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	0	61	attach	derived	87:93	arg2	composite					77:85	carbon composite	70:85	carbon composite derived from shrimp shell@cellulose	70:121	Highly efficient adsorption of Bisphenol A using NaHCO3/CO2 activated carbon composite derived from shrimp shell@cellulose.					
35554807	6	62	from	ratio	1078:1082	arg1	800°C					1134:1138	800°C	1134:1138	800°C	1134:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	5	63	theme	Langmuir	912:919	arg1	adsorption					921:930	the Langmuir adsorption	908:930	the Langmuir adsorption isotherm model	908:945	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	1	64	theme	shrimp	200:205	arg1	shell					207:211	the shrimp shell	196:211	the shrimp shell	196:211	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	2	65	theme	SS	426:427	arg1	C-AC					429:432	SS@C-AC	426:432	SS@C-AC	426:432	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	5	66	theme	adsorption	921:930	arg1	model					941:945	the Langmuir adsorption isotherm model	908:945	the Langmuir adsorption isotherm model	908:945	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	3	67	theme	mesoporous	506:515	arg1	structures					517:526	mesoporous structures	506:526	mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	506:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	4	68	from	influences	677:686	arg1	BPA					744:746	BPA	744:746	BPA	744:746	The influences of initial concentrations, pH values, and adsorption on BPA were investigated systematically.					
35554807	1	69	theme	activated	157:165	arg1	carbon					167:172	activated carbon	157:172	activated carbon (AC) synthesized from the shrimp shell	157:211	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	1	69	theme	activated	157:165	arg1	AC					175:176	AC	175:176	AC	175:176	In this study, the efficiency of activated carbon (AC) synthesized from the shrimp shell plus cellulose (SS@C) was optimized toward Bisphenol A (BPA) adsorption.					
35554807	6	70	theme	optimum	1149:1155	arg1	time					1116:1119	an activation time	1102:1119	an activation time of 90 min at 800°C	1102:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	70	theme	optimum	1149:1155	arg1	ratio					1078:1082	The impregnation ratio	1061:1082	The impregnation ratio of 1.5 NaHCO3	1061:1096	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	70	theme	optimum	1149:1155	arg1	conditions					1157:1166	the optimum conditions	1145:1166	the optimum conditions under which BPA removal of 81.78% was obtained	1145:1213	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	6	71	from	time	1116:1119	arg1	800°C					1134:1138	800°C	1134:1138	800°C	1134:1138	The impregnation ratio of 1.5 NaHCO3 and an activation time of 90 min at 800°C were the optimum conditions under which BPA removal of 81.78% was obtained.					
35554807	3	72	with	composite	491:499	arg1	structures					517:526	mesoporous structures	506:526	mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g	506:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	5	73	theme	obtained	871:878	arg1	data					880:883	the obtained data	867:883	the obtained data	867:883	Isotherm model and kinetics study of the adsorption of BPA on SS@C-AC exhibited that the obtained data were in agreement with the Langmuir adsorption isotherm model while there is no difference between PFO and PSO kinetic results for BPA concentrations in the range 25-100 mg/L.					
35554807	2	74	theme	renewable	296:304	arg1	shells					328:333	Low-cost, renewable, and non-toxic shrimp shells	286:333	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose	286:354	Low-cost, renewable, and non-toxic shrimp shells mixed with cellulose were carbonized, followed by activation via CO2 and NaHCO3 to produce SS@C-AC.					
35554807	3	75	theme	cm3/g	666:670	arg1	volume					647:652	mesoporous volume	636:652	mesoporous volume of 1.83E-02 cm3/g	636:670	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	75	theme	cm3/g	666:670	arg1	area					574:577	a relatively high specific surface area	539:577	a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm	539:630	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
35554807	3	75	theme	cm3/g	666:670	arg1	m2/g					587:590	935.20 m2/g	580:590	935.20 m2/g	580:590	The results revealed that SS@C-AC samples were a porous composite with mesoporous structures comprising a relatively high specific surface area (935.20 m2/g) with a mean pore size of around 3.8 nm and mesoporous volume of 1.83E-02 cm3/g.					
36363999	5	0	theme	chitosan	645:652	arg1	membrane					654:661	the chitosan membrane	641:661	the chitosan membrane	641:661	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	6	1	theme	specific	777:784	arg1	area					794:797	The specific surface area	773:797	The specific surface area of the chitosan membrane	773:822	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	9	2	theme	hydrogen	1310:1317	arg1	bonds					1319:1323	hydrogen bonds	1310:1323	hydrogen bonds	1310:1323	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	3	3	theme	gasification	432:443	arg1	slag					445:448	treated coal gasification slag	419:448	treated coal gasification slag	419:448	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	1	4	theme	heavy	195:199	arg1	ions					207:210	heavy metal ions	195:210	heavy metal ions	195:210	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	0	5	theme	Adsorption	76:85	arg1	Preparation					0:10	Preparation	0:10	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.	0:126	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	10	6	theme	membrane	1460:1467	arg1	properties					1433:1442	the mechanical properties	1418:1442	the mechanical properties of the chitosan membrane	1418:1467	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	7	7	theme	chitosan	977:984	arg1	membrane					986:993	the chitosan membrane	973:993	the chitosan membrane	973:993	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	5	8	theme	gasification	754:765	arg1	slag					767:770	coal gasification slag	749:770	coal gasification slag	749:770	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	1	9	theme	metal	201:205	arg1	ions					207:210	heavy metal ions	195:210	heavy metal ions	195:210	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	10	10	theme	coal	1383:1386	arg1	slag					1401:1404	coal gasification slag	1383:1404	coal gasification slag	1383:1404	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	0	11	from	Preparation	0:10	arg1	Water					121:125	Water	121:125	Water	121:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	8	12	theme	kinetics	1043:1050	arg1	analysis					1077:1084	the adsorption kinetics and adsorption mechanism analysis	1028:1084	the adsorption kinetics and adsorption mechanism analysis	1028:1084	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	5	13	theme	coal	749:752	arg1	slag					767:770	coal gasification slag	749:770	coal gasification slag	749:770	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	0	14	from	Water	121:125	arg1	Preparation					0:10	Preparation	0:10	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.	0:126	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	15	from	Membrane	59:66	arg1	Water					121:125	Water	121:125	Water	121:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	7	16	dep	μm	1014:1015	arg1	to					1007:1008	to	1007:1008	to	1007:1008	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	10	17	theme	mechanical	1422:1431	arg1	properties					1433:1442	the mechanical properties	1418:1442	the mechanical properties of the chitosan membrane	1418:1467	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	0	18	dep	Cr	102:103	arg1	VI					106:107	VI	106:107	VI	106:107	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	4	19	theme	membrane	508:515	arg1	mg/L					526:529	50.0 mg/L	521:529	50.0 mg/L	521:529	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	4	19	theme	membrane	508:515	arg1	Cr					455:456	The Cr (VI) maximum adsorption capacity of the composite membrane	451:515	The Cr (VI) maximum adsorption capacity of the composite membrane	451:515	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	5	20	theme	removal	625:631	arg1	rate					633:636	the removal rate	621:636	the removal rate of the chitosan membrane	621:661	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	5	20	theme	removal	625:631	arg1	%					689:689	only approximately 5.0%	667:689	only approximately 5.0%	667:689	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	10	21	theme	practical	1508:1516	arg1	application					1518:1528	the practical application	1504:1528	the practical application of the composite membrane	1504:1554	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	9	22	theme	gasification	1350:1361	arg1	slag					1363:1366	coal gasification slag	1345:1366	coal gasification slag	1345:1366	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	8	23	from	groups	1206:1211	arg1	chains					1230:1235	the molecular chains	1216:1235	the molecular chains of chitosan	1216:1247	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	3	24	theme	composite	356:364	arg1	material					375:382	a renewable composite membrane material	344:382	a renewable composite membrane material	344:382	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	0	25	theme	Cr	102:103	arg1	Adsorption					76:85	Its Adsorption	72:85	Its Adsorption	72:85	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	25	theme	Cr	102:103	arg1	Removal					91:97	Removal	91:97	Removal of Cr (VI) and RhB in Water	91:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	25	theme	Cr	102:103	arg1	Membrane					59:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	4	26	theme	composite	498:506	arg1	membrane					508:515	the composite membrane	494:515	the composite membrane	494:515	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	9	27	theme	slag	1363:1366	arg1	surface					1334:1340	the surface	1330:1340	the surface of coal gasification slag	1330:1366	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	7	28	dep	open	951:954	arg1	μm					1014:1015	80 μm to 110 μm	1001:1015	80 μm to 110 μm	1001:1015	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	3	29	theme	membrane	366:373	arg1	material					375:382	a renewable composite membrane material	344:382	a renewable composite membrane material	344:382	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	5	30	theme	membrane	654:661	arg1	rate					633:636	the removal rate	621:636	the removal rate of the chitosan membrane	621:661	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	5	30	theme	membrane	654:661	arg1	%					689:689	only approximately 5.0%	667:689	only approximately 5.0%	667:689	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	8	31	theme	coordination	1172:1183	arg1	bonds					1185:1189	coordination bonds	1172:1189	coordination bonds	1172:1189	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	11	32	theme	gasification	1652:1663	arg1	slag					1665:1668	coal gasification slag	1647:1668	coal gasification slag	1647:1668	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	10	33	theme	chitosan	1451:1458	arg1	membrane					1460:1467	the chitosan membrane	1447:1467	the chitosan membrane	1447:1467	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	4	34	theme	adsorption	471:480	arg1	capacity					482:489	maximum adsorption capacity	463:489	The Cr (VI) maximum adsorption capacity of the composite membrane	451:515	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	9	35	with	formation	1297:1305	arg1	surface					1334:1340	the surface	1330:1340	the surface of coal gasification slag	1330:1366	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	4	36	dep	Cr	455:456	arg1	VI					459:460	VI	459:460	VI	459:460	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	4	36	dep	Cr	455:456	arg1	capacity					482:489	maximum adsorption capacity	463:489	The Cr (VI) maximum adsorption capacity of the composite membrane	451:515	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	3	37	theme	renewable	346:354	arg1	material					375:382	a renewable composite membrane material	344:382	a renewable composite membrane material	344:382	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	7	38	theme	μm	1004:1005	arg1	μm					1014:1015	80 μm to 110 μm	1001:1015	80 μm to 110 μm	1001:1015	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	4	39	theme	maximum	463:469	arg1	capacity					482:489	maximum adsorption capacity	463:489	The Cr (VI) maximum adsorption capacity of the composite membrane	451:515	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	7	40	theme	coal	922:925	arg1	slag					940:943	coal gasification slag	922:943	coal gasification slag	922:943	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	8	41	theme	adsorption	1032:1041	arg1	kinetics					1043:1050	adsorption kinetics	1032:1050	adsorption kinetics	1032:1050	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	1	42	theme	many	150:153	arg1	dyes					186:189	dyes	186:189	dyes	186:189	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	1	42	theme	many	150:153	arg1	kinds					155:159	many kinds	150:159	many kinds	150:159	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	1	42	theme	many	150:153	arg1	ions					207:210	heavy metal ions	195:210	heavy metal ions	195:210	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	10	43	theme	gasification	1388:1399	arg1	slag					1401:1404	coal gasification slag	1383:1404	coal gasification slag	1383:1404	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	7	44	theme	gasification	927:938	arg1	slag					940:943	coal gasification slag	922:943	coal gasification slag	922:943	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	8	45	dep	kinetics	1043:1050	arg1	the					1028:1030	the	1028:1030	the	1028:1030	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	8	46	theme	bonds	1185:1189	arg1	formation					1159:1167	the formation	1155:1167	the formation of coordination bonds	1155:1189	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	9	47	theme	bonds	1319:1323	arg1	formation					1297:1305	the formation	1293:1305	the formation of hydrogen bonds with the surface of coal gasification slag	1293:1366	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	0	48	theme	Slag	44:47	arg1	Membrane					59:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	6	49	theme	membrane	815:822	arg1	area					794:797	The specific surface area	773:797	The specific surface area of the chitosan membrane	773:822	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	0	50	theme	RhB	114:116	arg1	Adsorption					76:85	Its Adsorption	72:85	Its Adsorption	72:85	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	50	theme	RhB	114:116	arg1	Removal					91:97	Removal	91:97	Removal of Cr (VI) and RhB in Water	91:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	50	theme	RhB	114:116	arg1	Membrane					59:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	51	from	Adsorption	76:85	arg1	Water					121:125	Water	121:125	Water	121:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	8	52	theme	amino	1200:1204	arg1	groups					1206:1211	the amino groups	1196:1211	the amino groups on the molecular chains of chitosan	1196:1247	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	6	53	theme	slag	900:903	arg1	introduction					866:877	the introduction	862:877	the introduction of coal gasification slag	862:903	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	8	54	theme	mechanism	1067:1075	arg1	analysis					1077:1084	the adsorption kinetics and adsorption mechanism analysis	1028:1084	the adsorption kinetics and adsorption mechanism analysis	1028:1084	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	6	55	theme	chitosan	806:813	arg1	membrane					815:822	the chitosan membrane	802:822	the chitosan membrane	802:822	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	5	56	theme	RhB	616:618	arg1	adsorption					602:611	the adsorption	598:611	the adsorption of RhB	598:618	For the adsorption of RhB, the removal rate of the chitosan membrane was only approximately 5.0%, but this value could be improved to 95.3% by introducing coal gasification slag.					
36363999	1	57	theme	pollutants	164:173	arg1	dyes					186:189	dyes	186:189	dyes	186:189	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	1	57	theme	pollutants	164:173	arg1	kinds					155:159	many kinds	150:159	many kinds	150:159	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	1	57	theme	pollutants	164:173	arg1	ions					207:210	heavy metal ions	195:210	heavy metal ions	195:210	At present, there are many kinds of pollutants, including dyes and heavy metal ions, in wastewater.					
36363999	0	58	theme	Membrane	59:66	arg1	Preparation					0:10	Preparation	0:10	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.	0:126	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	6	59	theme	gasification	887:898	arg1	slag					900:903	coal gasification slag	882:903	coal gasification slag	882:903	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	3	60	theme	treated	419:425	arg1	slag					445:448	treated coal gasification slag	419:448	treated coal gasification slag	419:448	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	0	61	theme	Composite	49:57	arg1	Membrane					59:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	a Chitosan/Coal Gasification Slag Composite Membrane	15:66	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	11	62	theme	new	1577:1579	arg1	insight					1581:1587	new insight	1577:1587	new insight into the adsorbent design	1577:1613	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	3	63	theme	coal	427:430	arg1	slag					445:448	treated coal gasification slag	419:448	treated coal gasification slag	419:448	In this study, a renewable composite membrane material was synthesized using chitosan and treated coal gasification slag.					
36363999	8	64	theme	chitosan	1240:1247	arg1	chains					1230:1235	the molecular chains	1216:1235	the molecular chains of chitosan	1216:1247	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	11	65	theme	resource	1623:1630	arg1	utilization					1632:1642	the resource utilization	1619:1642	the resource utilization of coal gasification slag	1619:1668	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	8	66	dep	Cr	1123:1124	arg1	VI					1127:1128	VI	1127:1128	VI	1127:1128	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	8	67	theme	molecular	1220:1228	arg1	chains					1230:1235	the molecular chains	1216:1235	the molecular chains of chitosan	1216:1247	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	8	68	theme	Cr	1123:1124	arg1	adsorption					1109:1118	the adsorption	1105:1118	the adsorption of Cr (VI)	1105:1129	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	10	69	theme	composite	1537:1545	arg1	membrane					1547:1554	the composite membrane	1533:1554	the composite membrane	1533:1554	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	6	70	theme	coal	882:885	arg1	slag					900:903	coal gasification slag	882:903	coal gasification slag	882:903	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	10	71	theme	membrane	1547:1554	arg1	application					1518:1528	the practical application	1504:1528	the practical application of the composite membrane	1504:1554	Additionally, coal gasification slag can improve the mechanical properties of the chitosan membrane by 2.2 times, which may facilitate the practical application of the composite membrane.					
36363999	11	72	theme	adsorbent	1598:1606	arg1	design					1608:1613	the adsorbent design	1594:1613	the adsorbent design	1594:1613	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	0	73	attach	Removal	91:97	arg2	Cr					102:103	Cr	102:103	Cr (VI)	102:108	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	73	attach	Removal	91:97	arg2	RhB					114:116	RhB	114:116	RhB	114:116	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	0	73	attach	Removal	91:97	arg3	Water					121:125	Water	121:125	Water	121:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	4	74	theme	chitosan	575:582	arg1	membrane					584:591	the chitosan membrane	571:591	the chitosan membrane	571:591	The Cr (VI) maximum adsorption capacity of the composite membrane was 50.0 mg/L, which was 4.3~8.8% higher than that of the chitosan membrane.					
36363999	11	75	theme	coal	1647:1650	arg1	slag					1665:1668	coal gasification slag	1647:1668	coal gasification slag	1647:1668	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	0	76	from	Removal	91:97	arg1	Water					121:125	Water	121:125	Water	121:125	Preparation of a Chitosan/Coal Gasification Slag Composite Membrane and Its Adsorption and Removal of Cr (VI) and RhB in Water.					
36363999	9	77	theme	RhB	1261:1263	arg1	Meanwhile					1250:1258	Meanwhile	1250:1258	Meanwhile	1250:1258	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	9	77	theme	RhB	1261:1263	arg1	adsorption					1265:1274	RhB adsorption	1261:1274	RhB adsorption	1261:1274	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	2	78	theme	metal	308:312	arg1	ions					314:317	heavy metal ions	302:317	heavy metal ions	302:317	It is very important to develop adsorbents that can simultaneously remove heavy metal ions and dyes.					
36363999	8	79	theme	adsorption	1056:1065	arg1	mechanism					1067:1075	adsorption mechanism	1056:1075	adsorption mechanism	1056:1075	Based on the adsorption kinetics and adsorption mechanism analysis, it was found that the adsorption of Cr (VI) occurred mainly through the formation of coordination bonds with the amino groups on the molecular chains of chitosan.					
36363999	9	80	theme	coal	1345:1348	arg1	slag					1363:1366	coal gasification slag	1345:1366	coal gasification slag	1345:1366	Meanwhile, RhB adsorption occurred through the formation of hydrogen bonds with the surface of coal gasification slag.					
36363999	7	81	theme	membrane	986:993	arg1	nanopores					960:968	the nanopores	956:968	the nanopores of the chitosan membrane	956:993	This is because coal gasification slag could open the nanopores of the chitosan membrane (from 80 μm to 110 μm).					
36363999	6	82	theme	surface	786:792	arg1	area					794:797	The specific surface area	773:797	The specific surface area of the chitosan membrane	773:822	The specific surface area of the chitosan membrane could also be increased 16.2 times by the introduction of coal gasification slag.					
36363999	2	83	theme	heavy	302:306	arg1	ions					314:317	heavy metal ions	302:317	heavy metal ions	302:317	It is very important to develop adsorbents that can simultaneously remove heavy metal ions and dyes.					
36363999	11	84	theme	slag	1665:1668	arg1	utilization					1632:1642	the resource utilization	1619:1642	the resource utilization of coal gasification slag	1619:1668	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
36363999	11	84	theme	slag	1665:1668	arg1	insight					1581:1587	new insight	1577:1587	new insight into the adsorbent design	1577:1613	This study provides new insight into the adsorbent design and the resource utilization of coal gasification slag.					
37336439	9	0	theme	anionic	2048:2054	arg1	wastewater					2060:2069	anionic dye wastewater	2048:2069	anionic dye wastewater with a wide pH range	2048:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	5	1	theme	adsorption	1156:1165	arg1	equilibrium					1167:1177	The adsorption equilibrium	1152:1177	The adsorption equilibrium of each dye	1152:1189	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	9	2	theme	natural	1814:1820	arg1	ingredients					1822:1832	natural ingredients	1814:1832	natural ingredients	1814:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	3	theme	wastewater	2060:2069	arg1	purification					2032:2043	the purification	2028:2043	the purification of anionic dye wastewater with a wide pH range	2028:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	8	4	theme	adsorption	1599:1608	arg1	performance					1610:1620	The ultrastrong adsorption performance	1583:1620	The ultrastrong adsorption performance	1583:1620	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	8	4	theme	adsorption	1599:1608	arg1	due					1626:1628	due	1626:1628	due	1626:1628	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	3	5	dep	performance	698:708	arg1	The					683:685	The	683:685	The	683:685	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	4	6	theme	magnetic	1073:1080	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	6	theme	magnetic	1073:1080	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	2	7	theme	Gly	475:477	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	7	theme	Gly	475:477	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	9	8	theme	@	1847:1847	arg1	composite					1854:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	9	theme	pH	2083:2084	arg1	range					2086:2090	a wide pH range	2076:2090	a wide pH range	2076:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	2	10	theme	@	569:569	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	10	theme	@	569:569	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	4	11	theme	abundant	1041:1048	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	11	theme	abundant	1041:1048	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	1	12	from	difficulty	303:312	arg1	applications					363:374	wastewater treatment applications	342:374	wastewater treatment applications	342:374	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	3	13	dep	direct	813:818	arg1	DR					873:874	DR 13	873:877	DR 13	873:877	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	13	dep	direct	813:818	arg1	13					869:870	13	869:870	13	869:870	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	13	dep	direct	813:818	arg1	CR					850:851	CR	850:851	CR	850:851	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	13	dep	direct	813:818	arg1	Blue					820:823	Blue	820:823	Blue	820:823	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	13	dep	direct	813:818	arg1	red					845:847	red	845:847	red	845:847	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	8	14	theme	multisite	1637:1645	arg1	interaction					1647:1657	the multisite interaction	1633:1657	the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions	1633:1746	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	3	15	theme	anionic	800:806	arg1	dyes					808:811	anionic dyes	800:811	anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13)	800:878	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	1	16	from	focus	293:297	arg1	applications					363:374	wastewater treatment applications	342:374	wastewater treatment applications	342:374	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	1	17	theme	adsorbent	253:261	arg1	materials					263:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	3	18	from	water	885:889	arg1	removal					789:795	the removal	785:795	the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water	785:889	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	9	19	theme	stronger	1883:1890	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	19	theme	stronger	1883:1890	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	19	theme	stronger	1883:1890	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	19	theme	stronger	1883:1890	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	20	theme	dye	2056:2058	arg1	wastewater					2060:2069	anionic dye wastewater	2048:2069	anionic dye wastewater with a wide pH range	2048:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	0	21	theme	eco-friendly	160:171	arg1	composite					173:181	an eco-friendly composite	157:181	an eco-friendly composite	157:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	8	22	theme	action	1678:1683	arg1	interaction					1647:1657	the multisite interaction	1633:1657	the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions	1633:1746	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	8	23	theme	various	1689:1695	arg1	bonds					1706:1710	various hydrogen bonds	1689:1710	various hydrogen bonds	1689:1710	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	1	24	dep	focus	293:297	arg1	the					289:291	the	289:291	the	289:291	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	9	25	theme	better	1915:1920	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	25	theme	better	1915:1920	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	25	theme	better	1915:1920	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	25	theme	better	1915:1920	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	5	26	theme	removal	1237:1243	arg1	%					1271:1271	more than 95%	1259:1271	more than 95%	1259:1271	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	5	26	theme	removal	1237:1243	arg1	efficiency					1245:1254	the removal efficiency	1233:1254	the removal efficiency	1233:1254	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	3	27	theme	direct	813:818	arg1	dyes					808:811	anionic dyes	800:811	anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13)	800:878	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	7	28	dep	DB	1538:1539	arg1	298 K					1562:1566	13 at 298 K	1556:1566	13 at 298 K	1556:1566	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	8	29	theme	bonds	1706:1710	arg1	interaction					1647:1657	the multisite interaction	1633:1657	the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions	1633:1746	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	2	30	theme	/yttrium	509:516	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	30	theme	/yttrium	509:516	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	4	31	theme	adsorption	1117:1126	arg1	ability					1128:1134	ultrastrong adsorption ability	1105:1134	ultrastrong adsorption ability	1105:1134	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	8	32	theme	hybrid	1720:1725	arg1	beads					1727:1731	hybrid beads	1720:1731	hybrid beads	1720:1731	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	5	33	dep	9.0	1320:1322	arg1	to					1317:1318	to	1317:1318	to	1317:1318	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	7	34	theme	adsorption	1482:1491	arg1	1635					1509:1512	1635	1509:1512	1635	1509:1512	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	7	34	theme	adsorption	1482:1491	arg1	capacities					1493:1502	the maximum adsorption capacities	1470:1502	the maximum adsorption capacities	1470:1502	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	2	35	theme	bead	541:544	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	35	theme	bead	541:544	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	36	theme	analytical	660:669	arg1	techniques					671:680	various modern analytical techniques	645:680	various modern analytical techniques	645:680	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	0	37	theme	amino	88:92	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	1	38	theme	dye	408:410	arg1	wastewater					412:421	dye wastewater	408:421	dye wastewater	408:421	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	2	39	theme	various	645:651	arg1	techniques					671:680	various modern analytical techniques	645:680	various modern analytical techniques	645:680	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	0	40	theme	diatomite/yttrium	114:130	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	4	41	theme	particle	974:981	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	41	theme	particle	974:981	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	41	theme	particle	974:981	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	0	42	from	mechanism	39:47	arg1	water					70:74	water	70:74	water	70:74	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	43	theme	Super-efficient	0:14	arg1	removal					16:22	Super-efficient removal	0:22	Super-efficient removal	0:22	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	7	44	theme	13 at	1556:1560	arg1	298 K					1562:1566	13 at 298 K	1556:1566	13 at 298 K	1556:1566	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	2	45	theme	magnetic	458:465	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	45	theme	magnetic	458:465	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	1	46	theme	technology	328:337	arg1	focus					293:297	focus	293:297	focus	293:297	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	1	46	theme	technology	328:337	arg1	development					188:198	The development	184:198	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials	184:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	1	46	theme	technology	328:337	arg1	difficulty					303:312	difficulty	303:312	difficulty	303:312	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	2	47	theme	Dia	505:507	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	47	theme	Dia	505:507	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	1	48	theme	wastewater	342:351	arg1	applications					363:374	wastewater treatment applications	342:374	wastewater treatment applications	342:374	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	7	49	theme	Langmuir	1445:1452	arg1	model					1454:1458	the Langmuir model	1441:1458	the Langmuir model	1441:1458	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	2	50	theme	diatomite	495:503	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	50	theme	diatomite	495:503	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	9	51	theme	good	1998:2001	arg1	prospect					2015:2022	a good application prospect	1996:2022	a good application prospect for the purification of anionic dye wastewater with a wide pH range	1996:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	0	52	theme	anionic	52:58	arg1	dyes					60:63	anionic dyes	52:63	anionic dyes from water	52:74	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	4	53	theme	surface	1022:1028	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	53	theme	surface	1022:1028	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	1	54	theme	materials	263:271	arg1	focus					293:297	focus	293:297	focus	293:297	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	1	54	theme	materials	263:271	arg1	development					188:198	The development	184:198	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials	184:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	7	55	theme	isotherm	1420:1427	arg1	data					1429:1432	All isotherm data	1416:1432	All isotherm data	1416:1432	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	9	56	contain	have	1991:1994	arg1	composite					1854:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	56	contain	have	1991:1994	arg2	prospect					2015:2022	a good application prospect	1996:2022	a good application prospect for the purification of anionic dye wastewater with a wide pH range	1996:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	4	57	theme	1.5 mm	997:1002	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	57	theme	1.5 mm	997:1002	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	57	theme	1.5 mm	997:1002	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	9	58	theme	wide	2078:2081	arg1	range					2086:2090	a wide pH range	2076:2090	a wide pH range	2076:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	6	59	theme	Pseudo-second-order	1376:1394	arg1	equation					1401:1408	the Pseudo-second-order rate equation	1372:1408	the Pseudo-second-order rate equation	1372:1408	The adsorption processes could be explained by the Pseudo-second-order rate equation well.					
37336439	2	60	theme	droplet	600:606	arg1	polymerization					608:621	the droplet polymerization	596:621	the droplet polymerization	596:621	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	4	61	theme	flower-like	1005:1015	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	61	theme	flower-like	1005:1015	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	3	62	theme	adsorption	714:723	arg1	mechanism					725:733	adsorption mechanism	714:733	adsorption mechanism	714:733	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	8	63	theme	ultrastrong	1587:1597	arg1	performance					1610:1620	The ultrastrong adsorption performance	1583:1620	The ultrastrong adsorption performance	1583:1620	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	8	63	theme	ultrastrong	1587:1597	arg1	due					1626:1628	due	1626:1628	due	1626:1628	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	9	64	theme	Dia-Gly-Y-SA	1835:1846	arg1	composite					1854:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	3	65	theme	composite	742:750	arg1	mechanism					725:733	adsorption mechanism	714:733	adsorption mechanism	714:733	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	65	theme	composite	742:750	arg1	performance					698:708	adsorption performance	687:708	adsorption performance	687:708	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	1	66	theme	eco-friendly	203:214	arg1	materials					263:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	4	67	with	gelpolymer	947:956	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	67	with	gelpolymer	947:956	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	67	with	gelpolymer	947:956	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	9	68	theme	application	2003:2013	arg1	prospect					2015:2022	a good application prospect	1996:2022	a good application prospect for the purification of anionic dye wastewater with a wide pH range	1996:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	4	69	theme	porosity	1050:1057	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	69	theme	porosity	1050:1057	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	1	70	theme	large-capacity	217:230	arg1	materials					263:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	2	71	theme	Dia-Gly-Y-SA	557:568	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	71	theme	Dia-Gly-Y-SA	557:568	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	4	72	theme	sensitive	1063:1071	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	72	theme	sensitive	1063:1071	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	9	73	theme	Fe3O4	1848:1852	arg1	composite					1854:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	Dia-Gly-Y-SA@Fe3O4 composite	1835:1862	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	3	74	dep	Blue	820:823	arg1	106					825:827	106	825:827	106	825:827	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	3	74	dep	Blue	820:823	arg1	DB					830:831	DB 106	830:835	DB 106	830:835	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	1	75	theme	easy-to-separate	236:251	arg1	materials					263:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	eco-friendly, large-capacity and easy-to-separate adsorbent materials	203:271	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	0	76	from	water	70:74	arg1	removal					16:22	Super-efficient removal	0:22	Super-efficient removal	0:22	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	76	from	water	70:74	arg1	mechanism					39:47	adsorption mechanism	28:47	adsorption mechanism	28:47	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	76	from	water	70:74	arg1	dyes					60:63	anionic dyes	52:63	anionic dyes from water	52:74	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	3	77	theme	dyes	808:811	arg1	removal					789:795	the removal	785:795	the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water	785:889	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	9	78	theme	adsorption	1892:1901	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	78	theme	adsorption	1892:1901	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	78	theme	adsorption	1892:1901	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	78	theme	adsorption	1892:1901	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	8	79	theme	physicochemical	1662:1676	arg1	action					1678:1683	physicochemical action	1662:1683	physicochemical action	1662:1683	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	9	80	theme	secondary	1944:1952	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	80	theme	secondary	1944:1952	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	80	theme	secondary	1944:1952	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	80	theme	secondary	1944:1952	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	5	81	from	pH	1276:1277	arg1	%					1271:1271	more than 95%	1259:1271	more than 95%	1259:1271	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	5	81	from	pH	1276:1277	arg1	efficiency					1245:1254	the removal efficiency	1233:1254	the removal efficiency	1233:1254	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	4	82	theme	ultrastrong	1105:1115	arg1	ability					1128:1134	ultrastrong adsorption ability	1105:1134	ultrastrong adsorption ability	1105:1134	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	9	83	theme	cost-effective	1754:1767	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	83	theme	cost-effective	1754:1767	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	83	theme	cost-effective	1754:1767	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	83	theme	cost-effective	1754:1767	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	2	84	theme	alginate	518:525	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	84	theme	alginate	518:525	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	0	85	theme	magnetic	79:86	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	8	86	theme	hydrogen	1697:1704	arg1	bonds					1706:1710	various hydrogen bonds	1689:1710	various hydrogen bonds	1689:1710	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	7	87	theme	maximum	1474:1480	arg1	1635					1509:1512	1635	1509:1512	1635	1509:1512	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	7	87	theme	maximum	1474:1480	arg1	capacities					1493:1502	the maximum adsorption capacities	1470:1502	the maximum adsorption capacities	1470:1502	All isotherm data fitted the Langmuir model well, and the maximum adsorption capacities were 1635, 2359 and 1165 mg/g for DB 106, CR and DR 13 at 298 K, respectively.					
37336439	0	88	theme	hybrid	141:146	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	89	from	removal	16:22	arg1	water					70:74	water	70:74	water	70:74	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	90	theme	acid-functionalized	94:112	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	2	91	theme	hybrid	534:539	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	91	theme	hybrid	534:539	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	92	theme	modern	653:658	arg1	techniques					671:680	various modern analytical techniques	645:680	various modern analytical techniques	645:680	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	0	93	theme	alginate	132:139	arg1	beads					148:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads	79:152	magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite	79:181	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	1	94	theme	wastewater	412:421	arg1	characteristics					389:403	the characteristics	385:403	the characteristics of dye wastewater	385:421	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	9	95	theme	magnetic	1769:1776	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	95	theme	magnetic	1769:1776	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	95	theme	magnetic	1769:1776	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	95	theme	magnetic	1769:1776	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	2	96	theme	Y-SA	528:531	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	96	theme	Y-SA	528:531	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	9	97	theme	powder	1969:1974	arg1	Dia					1976:1978	powder Dia	1969:1978	powder Dia	1969:1978	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	8	98	theme	dye	1737:1739	arg1	anions					1741:1746	dye anions	1737:1746	dye anions	1737:1746	The ultrastrong adsorption performance was due to the multisite interaction of physicochemical action and various hydrogen bonds between hybrid beads and dye anions.					
37336439	4	99	theme	average	966:972	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	99	theme	average	966:972	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	99	theme	average	966:972	arg1	response					1082:1089	abundant porosity and sensitive magnetic response	1041:1089	abundant porosity and sensitive magnetic response	1041:1089	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	0	100	theme	adsorption	28:37	arg1	mechanism					39:47	adsorption mechanism	28:47	adsorption mechanism	28:47	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	1	101	theme	adsorption	317:326	arg1	technology					328:337	adsorption technology	317:337	adsorption technology	317:337	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	2	102	theme	glycine	467:473	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	102	theme	glycine	467:473	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	103	theme	green	452:456	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	103	theme	green	452:456	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	6	104	theme	adsorption	1329:1338	arg1	processes					1340:1348	The adsorption processes	1325:1348	The adsorption processes	1325:1348	The adsorption processes could be explained by the Pseudo-second-order rate equation well.					
37336439	4	105	theme	macroparticle	933:945	arg1	composite					918:926	the composite	914:926	the composite	914:926	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	105	theme	macroparticle	933:945	arg1	gelpolymer					947:956	a macroparticle gelpolymer	931:956	a macroparticle gelpolymer	931:956	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	0	106	theme	dyes	60:63	arg1	removal					16:22	Super-efficient removal	0:22	Super-efficient removal	0:22	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	0	106	theme	dyes	60:63	arg1	mechanism					39:47	adsorption mechanism	28:47	adsorption mechanism	28:47	Super-efficient removal and adsorption mechanism of anionic dyes from water by magnetic amino acid-functionalized diatomite/yttrium alginate hybrid beads as an eco-friendly composite.					
37336439	1	107	theme	treatment	353:361	arg1	applications					363:374	wastewater treatment applications	342:374	wastewater treatment applications	342:374	The development of eco-friendly, large-capacity and easy-to-separate adsorbent materials has always been the focus and difficulty of adsorption technology in wastewater treatment applications based on the characteristics of dye wastewater.					
37336439	2	108	theme	-functionalized	479:493	arg1	composite					546:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite	450:554	a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4)	450:575	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	2	108	theme	-functionalized	479:493	arg1	Fe3O4					570:574	Dia-Gly-Y-SA@Fe3O4	557:574	Dia-Gly-Y-SA@Fe3O4	557:574	Therefore, in this study, a green magnetic glycine(Gly)-functionalized diatomite(Dia)/yttrium alginate (Y-SA) hybrid bead composite (Dia-Gly-Y-SA@Fe3O4) was synthesized by the droplet polymerization, and characterized by various modern analytical techniques.					
37336439	3	109	theme	adsorption	687:696	arg1	performance					698:708	adsorption performance	687:708	adsorption performance	687:708	The adsorption performance and adsorption mechanism of the composite were evaluated and elucidated by the removal of anionic dyes direct Blue 106 (DB 106), Congo red (CR) and direct red 13 (DR 13) from water.					
37336439	4	110	theme	fold	1017:1020	arg1	size					983:986	an average particle size	963:986	an average particle size of about 1.5 mm	963:1002	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	4	110	theme	fold	1017:1020	arg1	structure					1030:1038	flower-like fold surface structure	1005:1038	flower-like fold surface structure	1005:1038	The results show that the composite is a macroparticle gelpolymer with an average particle size of about 1.5 mm, flower-like fold surface structure, abundant porosity and sensitive magnetic response, and displays ultrastrong adsorption ability for three dyes.					
37336439	9	111	with	wastewater	2060:2069	arg1	range					2086:2090	a wide pH range	2076:2090	a wide pH range	2076:2090	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	5	112	theme	dye	1187:1189	arg1	equilibrium					1167:1177	The adsorption equilibrium	1152:1177	The adsorption equilibrium of each dye	1152:1189	The adsorption equilibrium of each dye can be reached quickly within 30 min, and the removal efficiency is more than 95% at pH 2.0 and decreases slightly with pH up to 9.0.					
37336439	9	113	theme	adsorbent	1792:1800	arg1	pollution					1954:1962	no secondary pollution	1941:1962	no secondary pollution	1941:1962	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	113	theme	adsorbent	1792:1800	arg1	collectability					1922:1935	better collectability	1915:1935	better collectability	1915:1935	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	113	theme	adsorbent	1792:1800	arg1	macroparticle					1778:1790	a cost-effective magnetic macroparticle adsorbent	1752:1800	a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients	1752:1832	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	9	113	theme	adsorbent	1792:1800	arg1	efficiency					1903:1912	much more stronger adsorption efficiency	1873:1912	much more stronger adsorption efficiency	1873:1912	As a cost-effective magnetic macroparticle adsorbent prepared by natural ingredients, Dia-Gly-Y-SA@Fe3O4 composite exhibits much more stronger adsorption efficiency, better collectability and no secondary pollution than powder Dia, and would have a good application prospect for the purification of anionic dye wastewater with a wide pH range.					
37336439	6	114	theme	rate	1396:1399	arg1	equation					1401:1408	the Pseudo-second-order rate equation	1372:1408	the Pseudo-second-order rate equation	1372:1408	The adsorption processes could be explained by the Pseudo-second-order rate equation well.					
36196822	7	0	theme	Langmuir	1058:1065	arg1	isotherms					1082:1090	the Langmuir and Freundlich isotherms	1054:1090	isotherms	1082:1090	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	6	1	theme	loading	838:844	arg1	dependent					874:882	dependent	874:882	dependent	874:882	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	6	1	theme	loading	838:844	arg1	capacity					846:853	The loading capacity	834:853	The loading capacity of the sorbent	834:868	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	1	2	theme	SiO2	154:157	arg1	nano-composite					130:143	A novel superparamagnetic nano-composite	104:143	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product	104:208	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	1	2	theme	SiO2	154:157	arg1	SiO2					154:157	Fe3O4@SiO2	148:157	Fe3O4@SiO2	148:157	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	6	3	theme	200	954:956	arg1	mg/L					958:961	mg/L	958:961	mg/L	958:961	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	0	4	theme	Metformin	93:101	arg1	Delivery					81:88	Delivery	81:88	Delivery	81:88	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	0	4	theme	Metformin	93:101	arg1	Loading					69:75	Loading	69:75	Loading	69:75	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	6	5	theme	sorbent	862:868	arg1	dependent					874:882	dependent	874:882	dependent	874:882	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	6	5	theme	sorbent	862:868	arg1	capacity					846:853	The loading capacity	834:853	The loading capacity of the sorbent	834:868	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	2	6	theme	@	252:252	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	7	dep	transform	300:308	arg1	infrared					310:317	infrared	310:317	transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer	300:432	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	8	8	theme	delivery	1285:1292	arg1	applications					1294:1305	drug delivery applications	1280:1305	drug delivery applications	1280:1305	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	3	9	theme	diabetes	526:533	arg1	medicine					535:542	an oral diabetes medicine	518:542	an oral diabetes medicine	518:542	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	3	9	theme	diabetes	526:533	arg1	metformin					507:515	metformin	507:515	metformin	507:515	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	2	10	theme	Fe3O4	247:251	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	5	11	theme	saline	819:824	arg1	medium					826:831	a phosphate-buffered saline medium	798:831	a phosphate-buffered saline medium	798:831	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	7	12	theme	best	1036:1039	arg1	fitting					1041:1047	the best fitting	1032:1047	the best fitting into the Langmuir and Freundlich isotherms	1032:1090	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	8	13	theme	SiO2	1198:1201	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	13	theme	SiO2	1198:1201	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	2	14	theme	@	246:246	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	15	theme	scanning	367:374	arg1	microscopy					385:394	scanning electron microscopy	367:394	scanning electron microscopy	367:394	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	15	theme	scanning	367:374	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	8	16	theme	low-cost	1236:1243	arg1	sorbent					1245:1251	a non-toxic and low-cost sorbent	1220:1251	a non-toxic and low-cost sorbent	1220:1251	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	2	17	theme	SiO2	242:245	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	1	18	theme	tragacanth	169:178	arg1	gum					180:182	tragacanth gum	169:182	tragacanth gum (TG)	169:187	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	1	18	theme	tragacanth	169:178	arg1	TG					185:186	TG	185:186	TG	185:186	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	0	19	theme	Tragacanth	18:27	arg1	SiO2					42:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	3	20	theme	metformin	507:515	arg1	delivery					495:502	delivery	495:502	delivery	495:502	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	3	20	theme	metformin	507:515	arg1	loading					483:489	loading	483:489	loading	483:489	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	2	21	dep	Fourier	292:298	arg1	transform					300:308	transform	300:308	transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer	300:432	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	7	22	theme	adsorption	988:997	arg1	isotherms					999:1007	the adsorption isotherms	984:1007	the adsorption isotherms for the drug	984:1020	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	8	23	theme	@	1197:1197	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	23	theme	@	1197:1197	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	0	24	theme	Superparamagnetic	0:16	arg1	SiO2					42:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	8	25	theme	prepared	1183:1190	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	25	theme	prepared	1183:1190	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	4	26	theme	optimization	633:644	arg1	method					646:651	a central composite design optimization method	606:651	a central composite design optimization method	606:651	The conditions for the loading of the drug were optimized by a central composite design optimization method.					
36196822	8	27	theme	drug	1280:1283	arg1	applications					1294:1305	drug delivery applications	1280:1305	drug delivery applications	1280:1305	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	2	28	theme	X-ray	351:355	arg1	analysis					357:364	energy dispersive X-ray analysis	333:364	energy dispersive X-ray analysis	333:364	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	28	theme	X-ray	351:355	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	0	29	theme	Fe3O4	36:40	arg1	SiO2					42:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	0	30	dep	Loading	69:75	arg1	the					65:67	the	65:67	the	65:67	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	2	31	theme	dynamic	400:406	arg1	scattering					414:423	dynamic light scattering	400:423	dynamic light scattering	400:423	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	31	theme	dynamic	400:406	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	32	theme	light	408:412	arg1	scattering					414:423	dynamic light scattering	400:423	dynamic light scattering	400:423	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	32	theme	light	408:412	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	7	33	theme	isotherms	999:1007	arg1	study					975:979	A study	973:979	A study of the adsorption isotherms for the drug	973:1020	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	4	34	theme	drug	583:586	arg1	loading					568:574	the loading	564:574	the loading of the drug	564:586	The conditions for the loading of the drug were optimized by a central composite design optimization method.					
36196822	2	35	theme	TG	253:254	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	1	36	theme	Fe3O4	148:152	arg1	SiO2					154:157	Fe3O4@SiO2	148:157	Fe3O4@SiO2	148:157	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	5	37	theme	maximum	743:749	arg1	release					760:766	its maximum in-vitro release	739:766	its maximum in-vitro release	739:766	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	5	38	theme	sorbent	692:698	arg1	efficiency					674:683	The maximum loading efficiency	654:683	The maximum loading efficiency of the sorbent for metformin	654:712	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	4	39	theme	central	608:614	arg1	method					646:651	a central composite design optimization method	606:651	a central composite design optimization method	606:651	The conditions for the loading of the drug were optimized by a central composite design optimization method.					
36196822	2	40	dep	microscopy	385:394	arg1	analyzer					425:432	analyzer	425:432	analyzer	425:432	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	8	41	theme	Fe3O4	1192:1196	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	41	theme	Fe3O4	1192:1196	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	4	42	theme	composite	616:624	arg1	method					646:651	a central composite design optimization method	606:651	a central composite design optimization method	606:651	The conditions for the loading of the drug were optimized by a central composite design optimization method.					
36196822	0	43	theme	@	41:41	arg1	SiO2					42:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	5	44	theme	in-vitro	751:758	arg1	release					760:766	its maximum in-vitro release	739:766	its maximum in-vitro release	739:766	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	8	45	theme	adsorbent	1206:1214	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	45	theme	adsorbent	1206:1214	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	7	46	theme	low	1099:1101	arg1	concentrations					1122:1135	the low and high metformin concentrations	1095:1135	the low and high metformin concentrations	1095:1135	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	5	47	theme	phosphate-buffered	800:817	arg1	saline					819:824	a phosphate-buffered saline	798:824	a phosphate-buffered saline medium	798:831	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	2	48	theme	electron	376:383	arg1	microscopy					385:394	scanning electron microscopy	367:394	scanning electron microscopy	367:394	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	48	theme	electron	376:383	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	7	49	theme	Freundlich	1071:1080	arg1	isotherms					1082:1090	the Langmuir and Freundlich isotherms	1054:1090	isotherms	1082:1090	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	6	50	theme	metformin	899:907	arg1	concentration					909:921	the initial metformin concentration	887:921	the initial metformin concentration	887:921	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	1	51	theme	novel	106:110	arg1	nano-composite					130:143	A novel superparamagnetic nano-composite	104:143	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product	104:208	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	1	51	theme	novel	106:110	arg1	SiO2					154:157	Fe3O4@SiO2	148:157	Fe3O4@SiO2	148:157	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	6	52	theme	initial	891:897	arg1	concentration					909:921	the initial metformin concentration	887:921	the initial metformin concentration	887:921	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36196822	5	53	theme	maximum	658:664	arg1	efficiency					674:683	The maximum loading efficiency	654:683	The maximum loading efficiency of the sorbent for metformin	654:712	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	1	54	theme	superparamagnetic	112:128	arg1	nano-composite					130:143	A novel superparamagnetic nano-composite	104:143	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product	104:208	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	1	54	theme	superparamagnetic	112:128	arg1	SiO2					154:157	Fe3O4@SiO2	148:157	Fe3O4@SiO2	148:157	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	5	55	theme	loading	666:672	arg1	efficiency					674:683	The maximum loading efficiency	654:683	The maximum loading efficiency of the sorbent for metformin	654:712	The maximum loading efficiency of the sorbent for metformin was obtained at pH 7 and its maximum in-vitro release was achieved at pH 1.6, using a phosphate-buffered saline medium.					
36196822	7	56	theme	high	1107:1110	arg1	concentrations					1122:1135	the low and high metformin concentrations	1095:1135	the low and high metformin concentrations	1095:1135	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	2	57	theme	obtained	233:240	arg1	nanoparticles					256:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles	229:268	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	8	58	theme	non-toxic	1222:1230	arg1	sorbent					1245:1251	a non-toxic and low-cost sorbent	1220:1251	a non-toxic and low-cost sorbent	1220:1251	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	1	59	theme	natural	194:200	arg1	product					202:208	a natural product	192:208	a natural product	192:208	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	3	60	dep	loading	483:489	arg1	the					479:481	the	479:481	the	479:481	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	3	61	theme	oral	521:524	arg1	medicine					535:542	an oral diabetes medicine	518:542	an oral diabetes medicine	518:542	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	3	61	theme	oral	521:524	arg1	metformin					507:515	metformin	507:515	metformin	507:515	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	1	62	theme	@	153:153	arg1	SiO2					154:157	Fe3O4@SiO2	148:157	Fe3O4@SiO2	148:157	A novel superparamagnetic nano-composite of Fe3O4@SiO2 coated by tragacanth gum (TG) as a natural product has been prepared.					
36196822	3	63	theme	magnetic	439:446	arg1	nano-composite					448:461	The magnetic nano-composite	435:461	The magnetic nano-composite	435:461	The magnetic nano-composite was applied for the loading and delivery of metformin, an oral diabetes medicine.					
36196822	8	64	theme	@	1202:1202	arg1	appropriate					1264:1274	appropriate	1264:1274	appropriate	1264:1274	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	8	64	theme	@	1202:1202	arg1	TG					1203:1204	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	the prepared Fe3O4@SiO2@TG adsorbent	1179:1214	The results indicated that the prepared Fe3O4@SiO2@TG adsorbent, as a non-toxic and low-cost sorbent, was quite appropriate for drug delivery applications.					
36196822	2	65	theme	dispersive	340:349	arg1	analysis					357:364	energy dispersive X-ray analysis	333:364	energy dispersive X-ray analysis	333:364	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	65	theme	dispersive	340:349	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	4	66	theme	design	626:631	arg1	method					646:651	a central composite design optimization method	606:651	a central composite design optimization method	606:651	The conditions for the loading of the drug were optimized by a central composite design optimization method.					
36196822	0	67	theme	Coated	29:34	arg1	SiO2					42:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2	0:45	Superparamagnetic Tragacanth Coated Fe3O4@SiO2 Nanoparticles for the Loading and Delivery of Metformin.					
36196822	2	68	theme	energy	333:338	arg1	analysis					357:364	energy dispersive X-ray analysis	333:364	energy dispersive X-ray analysis	333:364	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	2	68	theme	energy	333:338	arg1	spectroscopy					319:330	spectroscopy	319:330	spectroscopy	319:330	The obtained SiO2@Fe3O4@TG nanoparticles were characterized by Fourier transform infrared spectroscopy, energy dispersive X-ray analysis, scanning electron microscopy and dynamic light scattering analyzer.					
36196822	7	69	theme	metformin	1112:1120	arg1	concentrations					1122:1135	the low and high metformin concentrations	1095:1135	the low and high metformin concentrations	1095:1135	A study of the adsorption isotherms for the drug indicated the best fitting into the Langmuir and Freundlich isotherms at the low and high metformin concentrations, respectively.					
36196822	6	70	theme	mg/L	958:961	arg1	solution					963:970	a 200 mg/L solution	952:970	a 200 mg/L solution	952:970	The loading capacity of the sorbent was dependent on the initial metformin concentration and exceeded to 19.6 mg/g in a 200 mg/L solution.					
36822283	4	0	theme	Scanning	597:604	arg1	Microscope					615:624	Scanning Electron Microscope	597:624	Scanning Electron Microscope	597:624	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	6	1	theme	PCL	943:945	arg1	temperature					928:938	the crystallization temperature	908:938	the crystallization temperature of PCL	908:945	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	5	2	theme	DSC	813:815	arg1	test					829:832	DSC and tensile test	813:832	test	829:832	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	0	3	theme	agricultural	77:88	arg1	wastes					90:95	agricultural wastes	77:95	agricultural wastes	77:95	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	1	4	theme	orange	152:157	arg1	peel					159:162	orange peel	152:162	orange peel	152:162	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	6	5	theme	PCL	991:993	arg1	process					980:986	the crystallization process	960:986	the crystallization process of PCL	960:993	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	2	6	theme	agricultural	280:291	arg1	wastes					293:298	the three different agricultural wastes	260:298	the three different agricultural wastes	260:298	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	3	7	theme	wheat	482:486	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	7	theme	wheat	482:486	arg1	bran					488:491	wheat bran	482:491	wheat bran	482:491	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	2	8	theme	different	270:278	arg1	wastes					293:298	the three different agricultural wastes	260:298	the three different agricultural wastes	260:298	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	4	9	theme	Infrared	635:642	arg1	spectrometer					644:655	Fourier Infrared spectrometer	627:655	Fourier Infrared spectrometer	627:655	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	4	10	theme	Electron	606:613	arg1	Microscope					615:624	Scanning Electron Microscope	597:624	Scanning Electron Microscope	597:624	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	4	11	theme	Fourier	627:633	arg1	spectrometer					644:655	Fourier Infrared spectrometer	627:655	Fourier Infrared spectrometer	627:655	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	2	12	used	used	336:339	arg2	poly					305:308	poly	305:308	poly(ε-caprolactone) (PCL)	305:330	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	2	12	used	used	336:339	arg2	material					355:362	the matrix material	344:362	the matrix material	344:362	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	2	12	used	used	336:339	arg2	PCL					327:329	PCL	327:329	PCL	327:329	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	2	12	used	used	336:339	arg2	ε-caprolactone					310:323	ε-caprolactone	310:323	ε-caprolactone	310:323	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	6	13	theme	crystallization	912:926	arg1	temperature					928:938	the crystallization temperature	908:938	the crystallization temperature of PCL	908:945	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	5	14	theme	PCL	789:791	arg1	process					752:758	crystallization process	736:758	crystallization process	736:758	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	5	14	theme	PCL	789:791	arg1	properties					775:784	mechanical properties	764:784	mechanical properties	764:784	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	4	15	theme	cellulose	571:579	arg1	structure					544:552	structure	544:552	structure	544:552	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	4	15	theme	cellulose	571:579	arg1	Morphology					529:538	Morphology	529:538	Morphology	529:538	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	2	16	theme	matrix	348:353	arg1	material					355:362	the matrix material	344:362	the matrix material	344:362	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	2	16	theme	matrix	348:353	arg1	poly					305:308	poly	305:308	poly(ε-caprolactone) (PCL)	305:330	Cellulose was extracted from the three different agricultural wastes, and poly(ε-caprolactone) (PCL) was used as the matrix material.					
36822283	1	17	theme	wheat	168:172	arg1	bran					174:177	wheat bran	168:177	wheat bran	168:177	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	3	18	theme	nanocrystalline	384:398	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	18	theme	nanocrystalline	384:398	arg1	cellulose					463:471	orange peel cellulose	451:471	orange peel cellulose (JC)	451:476	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	18	theme	nanocrystalline	384:398	arg1	bran					488:491	wheat bran	482:491	wheat bran	482:491	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	18	theme	nanocrystalline	384:398	arg1	cellulose					435:443	extracted bagasse cellulose	417:443	extracted bagasse cellulose (GC)	417:448	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	18	theme	nanocrystalline	384:398	arg1	CNC					411:413	CNC	411:413	CNC	411:413	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	6	19	theme	crystallization	964:978	arg1	process					980:986	the crystallization process	960:986	the crystallization process of PCL	960:993	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	4	20	theme	X-ray	679:683	arg1	diffractometer					685:698	X-ray diffractometer	679:698	X-ray diffractometer	679:698	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	5	21	theme	crystallization	736:750	arg1	process					752:758	crystallization process	736:758	crystallization process	736:758	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	1	22	theme	rational	106:113	arg1	use					115:117	the rational use	102:117	the rational use of agricultural wastes	102:140	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	3	23	theme	extracted	417:425	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	23	theme	extracted	417:425	arg1	GC					446:447	GC	446:447	GC	446:447	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	23	theme	extracted	417:425	arg1	cellulose					435:443	extracted bagasse cellulose	417:443	extracted bagasse cellulose (GC)	417:448	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	0	24	theme	composites	42:51	arg1	research					16:23	research	16:23	research	16:23	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	0	24	theme	composites	42:51	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	0	25	theme	PCL/cellulose	28:40	arg1	composites					42:51	PCL/cellulose composites	28:51	PCL/cellulose composites	28:51	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	5	26	theme	GC	718:719	arg1	influence					705:713	The influence	701:713	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL	701:791	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	0	27	attach	derived	64:70	arg2	Cellulose					54:62	Cellulose	54:62	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.	0:96	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	0	27	attach	derived	64:70	arg1	wastes					90:95	agricultural wastes	77:95	agricultural wastes	77:95	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	5	28	theme	mechanical	764:773	arg1	properties					775:784	mechanical properties	764:784	mechanical properties	764:784	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	6	29	theme	CNC	882:884	arg1	addition					870:877	the addition	866:877	the addition of CNC, GC, JC, MC	866:896	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	1	30	used	used	184:187	arg2	peel					159:162	orange peel	152:162	orange peel	152:162	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	1	30	used	used	184:187	arg2	bagasse					143:149	bagasse	143:149	bagasse	143:149	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	1	30	used	used	184:187	arg2	bran					174:177	wheat bran	168:177	wheat bran	168:177	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	3	31	dep	cellulose	463:471	arg1	cellulose					493:501	cellulose	493:501	cellulose	493:501	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	32	theme	bagasse	427:433	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	32	theme	bagasse	427:433	arg1	GC					446:447	GC	446:447	GC	446:447	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	32	theme	bagasse	427:433	arg1	cellulose					435:443	extracted bagasse cellulose	417:443	extracted bagasse cellulose (GC)	417:448	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	6	33	theme	tensile	1013:1019	arg1	property					1021:1028	the tensile property	1009:1028	the tensile property of PCL	1009:1035	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	5	34	dep	process	752:758	arg1	the					732:734	the	732:734	the	732:734	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	5	35	from	influence	705:713	arg1	process					752:758	crystallization process	736:758	crystallization process	736:758	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	5	35	from	influence	705:713	arg1	properties					775:784	mechanical properties	764:784	mechanical properties	764:784	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	1	36	theme	agricultural	122:133	arg1	wastes					135:140	agricultural wastes	122:140	agricultural wastes	122:140	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	6	37	theme	PCL	1033:1035	arg1	property					1021:1028	the tensile property	1009:1028	the tensile property of PCL	1009:1035	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	1	38	theme	bio-based	202:210	arg1	materials					220:228	bio-based polymer materials	202:228	bio-based polymer materials	202:228	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	5	39	theme	tensile	821:827	arg1	test					829:832	DSC and tensile test	813:832	test	829:832	The influence of GC, JC, MC on the crystallization process and mechanical properties of PCL was investigated by DSC and tensile test.					
36822283	1	40	theme	wastes	135:140	arg1	use					115:117	the rational use	102:117	the rational use of agricultural wastes	102:140	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	1	41	theme	polymer	212:218	arg1	materials					220:228	bio-based polymer materials	202:228	bio-based polymer materials	202:228	For the rational use of agricultural wastes, bagasse, orange peel and wheat bran were used to fabricate bio-based polymer materials.					
36822283	3	42	theme	solution	511:518	arg1	casting					520:526	solution casting	511:526	solution casting	511:526	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	43	theme	orange	451:456	arg1	JC					474:475	JC	474:475	JC	474:475	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	43	theme	orange	451:456	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	43	theme	orange	451:456	arg1	cellulose					463:471	orange peel cellulose	451:471	orange peel cellulose (JC)	451:476	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	43	theme	orange	451:456	arg1	MC					504:505	MC	504:505	MC	504:505	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	4	44	theme	extracted	561:569	arg1	cellulose					571:579	the extracted cellulose	557:579	the extracted cellulose	557:579	Morphology and structure of the extracted cellulose were studied by Scanning Electron Microscope, Fourier Infrared spectrometer, thermogravimetry and X-ray diffractometer.					
36822283	6	45	theme	Experimental	835:846	arg1	results					848:854	Experimental results	835:854	Experimental results	835:854	Experimental results show that the addition of CNC, GC, JC, MC increases the crystallization temperature of PCL, accelerates the crystallization process of PCL, and improves the tensile property of PCL.					
36822283	0	46	dep	Preparation	0:10	arg1	Cellulose					54:62	Cellulose	54:62	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.	0:96	Preparation and research of PCL/cellulose composites: Cellulose derived from agricultural wastes.					
36822283	3	47	theme	peel	458:461	arg1	JC					474:475	JC	474:475	JC	474:475	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	47	theme	peel	458:461	arg1	cellulose					400:408	nanocrystalline cellulose	384:408	nanocrystalline cellulose (CNC)	384:414	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	47	theme	peel	458:461	arg1	cellulose					463:471	orange peel cellulose	451:471	orange peel cellulose (JC)	451:476	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
36822283	3	47	theme	peel	458:461	arg1	MC					504:505	MC	504:505	MC	504:505	PCL was mixed with nanocrystalline cellulose (CNC), extracted bagasse cellulose (GC), orange peel cellulose (JC) and wheat bran cellulose (MC) by solution casting.					
35581209	1	0	theme	nervous	259:265	arg1	etc					336:338	etc	336:338	etc	336:338	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	0	theme	nervous	259:265	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	0	theme	nervous	259:265	arg1	system					285:290	digestive system	275:290	digestive system	275:290	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	0	theme	nervous	259:265	arg1	system					308:313	cardiovascular system	293:313	cardiovascular system	293:313	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	0	theme	nervous	259:265	arg1	system					328:333	respiratory system	316:333	respiratory system	316:333	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	10	1	theme	porous	1626:1631	arg1	starch					1633:1638	porous starch	1626:1638	porous starch	1626:1638	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	5	2	theme	solid	737:741	arg1	material					751:758	a solid carrier material	735:758	a solid carrier material	735:758	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	5	2	theme	solid	737:741	arg1	starch					716:721	porous starch	709:721	porous starch	709:721	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	10	3	theme	physical	1644:1651	arg1	adsorption					1653:1662	physical adsorption	1644:1662	physical adsorption	1644:1662	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	10	3	theme	physical	1644:1651	arg1	adsorption					1592:1601	the adsorption	1588:1601	the adsorption of the volatile oil by porous starch	1588:1638	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	11	4	theme	volatile	1709:1716	arg1	oil					1718:1720	the porous starch-solidified volatile oil	1680:1720	the porous starch-solidified volatile oil	1680:1720	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	7	5	theme	starch	1051:1056	arg1	powder					1058:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	1	6	theme	various	179:185	arg1	activities					198:207	various biological activities	179:207	various biological activities	179:207	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	10	7	theme	chemical	1502:1509	arg1	composition					1511:1521	chemical composition	1502:1521	chemical composition	1502:1521	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	11	8	theme	porous	1684:1689	arg1	oil					1718:1720	the porous starch-solidified volatile oil	1680:1720	the porous starch-solidified volatile oil	1680:1720	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	7	9	theme	volatile	1031:1038	arg1	powder					1058:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	9	10	theme	retention	1384:1392	arg1	time					1394:1397	peak retention time	1379:1397	peak retention time	1379:1397	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	6	11	theme	solidified	899:908	arg1	powder					910:915	solidified powder	899:915	solidified powder	899:915	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	4	12	theme	preparation	615:625	arg1	process					627:633	the preparation process	611:633	the preparation process	611:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	11	13	theme	slow-release	1728:1739	arg1	effect					1741:1746	a slow-release effect	1726:1746	a slow-release effect	1726:1746	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	5	14	theme	liquid	765:770	arg1	oil					781:783	liquid volatile oil	765:783	liquid volatile oil	765:783	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	6	15	theme	oil	894:896	arg1	constituents					865:876	the chemical constituents	852:876	the chemical constituents of the volatile oil, solidified powder and tablets	852:927	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	10	16	theme	volatile	1530:1537	arg1	oil					1539:1541	the volatile oil	1526:1541	the volatile oil	1526:1541	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	1	17	from	activities	233:242	arg1	etc					336:338	etc	336:338	etc	336:338	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	17	from	activities	233:242	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	17	from	activities	233:242	arg1	system					285:290	digestive system	275:290	digestive system	275:290	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	17	from	activities	233:242	arg1	system					308:313	cardiovascular system	293:313	cardiovascular system	293:313	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	17	from	activities	233:242	arg1	system					328:333	respiratory system	316:333	respiratory system	316:333	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	6	18	theme	34	962:963	arg1	constituents					974:985	34 chemical constituents	962:985	34 chemical constituents	962:985	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	4	19	theme	stable	659:664	arg1	release					666:672	stable release	659:672	stable release	659:672	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	6	20	used	used	834:837	arg2	GC-MS					824:828	GC-MS	824:828	GC-MS	824:828	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	5	21	theme	porous	709:714	arg1	material					751:758	a solid carrier material	735:758	a solid carrier material	735:758	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	5	21	theme	porous	709:714	arg1	starch					716:721	porous starch	709:721	porous starch	709:721	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	0	22	theme	sustained-release	58:74	arg1	effect					76:81	the sustained-release effect	54:81	the sustained-release effect of volatile oil	54:97	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	1	23	theme	traditional	146:156	arg1	medicine					166:173	traditional Chinese medicine	146:173	traditional Chinese medicine	146:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	3	24	theme	high	529:532	arg1	volatility					534:543	high volatility	529:543	high volatility	529:543	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	2	25	used	used	363:366	arg2	oils					347:350	These oils	341:350	These oils	341:350	These oils are widely used in clinical practice.					
35581209	3	26	theme	clinical	424:431	arg1	applications					433:444	their clinical applications	418:444	their clinical applications	418:444	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	7	27	theme	volatile	1124:1131	arg1	oil					1133:1135	the volatile oil	1120:1135	the volatile oil	1120:1135	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	5	28	used	used	727:730	arg2	material					751:758	a solid carrier material	735:758	a solid carrier material	735:758	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	5	28	used	used	727:730	arg2	starch					716:721	porous starch	709:721	porous starch	709:721	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	8	29	theme	starch	1292:1297	arg1	ratio					1299:1303	the porous starch ratio	1281:1303	the porous starch ratio in the formulation	1281:1322	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	2	30	theme	clinical	371:378	arg1	practice					380:387	clinical practice	371:387	clinical practice	371:387	These oils are widely used in clinical practice.					
35581209	1	31	theme	digestive	275:283	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	31	theme	digestive	275:283	arg1	system					285:290	digestive system	275:290	digestive system	275:290	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	11	32	theme	high	1812:1815	arg1	value					1829:1833	high application value	1812:1833	high application value	1812:1833	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	5	33	theme	volatile	772:779	arg1	oil					781:783	liquid volatile oil	765:783	liquid volatile oil	765:783	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	8	34	theme	oil	1246:1248	arg1	release					1222:1228	the stable release	1211:1228	the stable release of the volatile oil	1211:1248	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	1	35	contain	has	175:177	arg1	oil					137:139	Volatile oil	128:139	Volatile oil from traditional Chinese medicine	128:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	35	contain	has	175:177	arg2	activities					198:207	various biological activities	179:207	various biological activities	179:207	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	36	theme	Chinese	158:164	arg1	medicine					166:173	traditional Chinese medicine	146:173	traditional Chinese medicine	146:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	0	37	theme	rules	28:32	arg1	Study					0:4	Study	0:4	Study of the volatilization rules of volatile oil	0:48	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	0	37	theme	rules	28:32	arg1	effect					76:81	the sustained-release effect	54:81	the sustained-release effect of volatile oil	54:97	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	6	38	theme	constituents	974:985	arg1	rules					953:957	the volatilization rules	934:957	the volatilization rules of 34 chemical constituents	934:985	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	10	39	theme	oil	1619:1621	arg1	adsorption					1653:1662	physical adsorption	1644:1662	physical adsorption	1644:1662	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	10	39	theme	oil	1619:1621	arg1	adsorption					1592:1601	the adsorption	1588:1601	the adsorption of the volatile oil by porous starch	1588:1638	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	0	40	theme	volatile	37:44	arg1	oil					46:48	volatile oil	37:48	volatile oil	37:48	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	1	41	theme	respiratory	316:326	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	41	theme	respiratory	316:326	arg1	system					328:333	respiratory system	316:333	respiratory system	316:333	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	9	42	dep	time	1394:1397	arg1	the					1375:1377	the	1375:1377	the	1375:1377	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	1	43	theme	pharmacological	217:231	arg1	activities					233:242	pharmacological activities	217:242	pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc	217:338	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	5	44	theme	carrier	743:749	arg1	material					751:758	a solid carrier material	735:758	a solid carrier material	735:758	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	5	44	theme	carrier	743:749	arg1	starch					716:721	porous starch	709:721	porous starch	709:721	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	3	45	theme	oils	497:500	arg1	stability					554:562	poor stability	549:562	poor stability	549:562	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	3	45	theme	oils	497:500	arg1	disadvantages					471:483	the disadvantages	467:483	the disadvantages	467:483	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	3	45	theme	oils	497:500	arg1	volatility					534:543	high volatility	529:543	high volatility	529:543	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	3	45	theme	oils	497:500	arg1	stimulation					516:526	high stimulation	511:526	high stimulation	511:526	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	8	46	from	ratio	1299:1303	arg1	formulation					1312:1322	the formulation	1308:1322	the formulation	1308:1322	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	1	47	theme	central	251:257	arg1	etc					336:338	etc	336:338	etc	336:338	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	47	theme	central	251:257	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	47	theme	central	251:257	arg1	system					285:290	digestive system	275:290	digestive system	275:290	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	47	theme	central	251:257	arg1	system					308:313	cardiovascular system	293:313	cardiovascular system	293:313	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	47	theme	central	251:257	arg1	system					328:333	respiratory system	316:333	respiratory system	316:333	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	6	48	theme	chemical	856:863	arg1	constituents					865:876	the chemical constituents	852:876	the chemical constituents of the volatile oil, solidified powder and tablets	852:927	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	10	49	theme	physical	1478:1485	arg1	properties					1487:1496	The physical properties	1474:1496	The physical properties	1474:1496	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	3	50	theme	high	511:514	arg1	stimulation					516:526	high stimulation	511:526	high stimulation	511:526	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	5	51	theme	physical	803:810	arg1	adsorption					812:821	physical adsorption	803:821	physical adsorption	803:821	In this paper, porous starch was used as a solid carrier material, and liquid volatile oil was solidified by physical adsorption.					
35581209	4	52	from	stability	580:588	arg1	process					627:633	the preparation process	611:633	the preparation process	611:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	7	53	theme	oil/porous	1040:1049	arg1	powder					1058:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	3	54	theme	poor	549:552	arg1	stability					554:562	poor stability	549:562	poor stability	549:562	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	4	55	from	process	627:633	arg1	stability					580:588	the stability	576:588	the stability of a volatile oil in the preparation process	576:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	6	56	theme	tablets	921:927	arg1	constituents					865:876	the chemical constituents	852:876	the chemical constituents of the volatile oil, solidified powder and tablets	852:927	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	0	57	theme	porous	113:118	arg1	starch					120:125	porous starch	113:125	porous starch	113:125	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	1	58	theme	biological	187:196	arg1	activities					198:207	various biological activities	179:207	various biological activities	179:207	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	6	59	theme	powder	910:915	arg1	constituents					865:876	the chemical constituents	852:876	the chemical constituents of the volatile oil, solidified powder and tablets	852:927	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	4	60	theme	oil	604:606	arg1	stability					580:588	the stability	576:588	the stability of a volatile oil in the preparation process	576:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	3	61	theme	volatile	488:495	arg1	oils					497:500	volatile oils	488:500	volatile oils	488:500	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	4	62	from	oil	604:606	arg1	process					627:633	the preparation process	611:633	the preparation process	611:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35581209	10	63	theme	oil	1539:1541	arg1	properties					1487:1496	The physical properties	1474:1496	The physical properties	1474:1496	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	10	63	theme	oil	1539:1541	arg1	composition					1511:1521	chemical composition	1502:1521	chemical composition	1502:1521	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	7	64	theme	oil	1133:1135	arg1	VOCs					1112:1115	the VOCs	1108:1115	the VOCs of the volatile oil before and after solidification	1108:1167	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	9	65	theme	chemical	1403:1410	arg1	composition					1412:1422	chemical composition	1403:1422	chemical composition	1403:1422	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	6	66	theme	volatile	885:892	arg1	oil					894:896	the volatile oil	881:896	the volatile oil	881:896	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	7	67	theme	solidified	1020:1029	arg1	powder					1058:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder	1016:1063	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	8	68	theme	stable	1215:1220	arg1	release					1222:1228	the stable release	1211:1228	the stable release of the volatile oil	1211:1248	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	6	69	theme	chemical	965:972	arg1	constituents					974:985	34 chemical constituents	962:985	34 chemical constituents	962:985	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	9	70	theme	peak	1379:1382	arg1	time					1394:1397	peak retention time	1379:1397	peak retention time	1379:1397	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	1	71	theme	Volatile	128:135	arg1	oil					137:139	Volatile oil	128:139	Volatile oil from traditional Chinese medicine	128:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	8	72	theme	volatile	1237:1244	arg1	oil					1246:1248	the volatile oil	1233:1248	the volatile oil	1233:1248	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	11	73	contain	has	1808:1810	arg2	value					1829:1833	high application value	1812:1833	high application value	1812:1833	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	73	contain	has	1808:1810	arg1	easy					1787:1790	easy	1787:1790	easy	1787:1790	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	73	contain	has	1808:1810	arg1	simple					1779:1784	simple	1779:1784	simple	1779:1784	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	73	contain	has	1808:1810	arg1	process					1768:1774	the production process	1753:1774	the production process	1753:1774	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	1	74	from	medicine	166:173	arg1	oil					137:139	Volatile oil	128:139	Volatile oil from traditional Chinese medicine	128:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	6	75	theme	volatilization	938:951	arg1	rules					953:957	the volatilization rules	934:957	the volatilization rules of 34 chemical constituents	934:985	GC-MS was used to determine the chemical constituents of the volatile oil, solidified powder and tablets, and the volatilization rules of 34 chemical constituents were analysed statistically.					
35581209	0	76	theme	volatile	86:93	arg1	oil					95:97	volatile oil	86:97	volatile oil	86:97	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	9	77	with	consistent	1435:1444	arg1	theory					1455:1460	the theory	1451:1460	the theory of flavour	1451:1471	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	9	78	theme	flavour	1465:1471	arg1	theory					1455:1460	the theory	1451:1460	the theory of flavour	1451:1471	Volatilization was shown to be closely related to the peak retention time and chemical composition, which was consistent with the theory of flavour.					
35581209	3	79	theme	applications	433:444	arg1	development					403:413	the development	399:413	the development of their clinical applications	399:444	However, the development of their clinical applications is restricted due to the disadvantages of volatile oils, such as high stimulation, high volatility and poor stability.					
35581209	11	80	theme	starch-solidified	1691:1707	arg1	oil					1718:1720	the porous starch-solidified volatile oil	1680:1720	the porous starch-solidified volatile oil	1680:1720	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	8	81	theme	porous	1285:1290	arg1	ratio					1299:1303	the porous starch ratio	1281:1303	the porous starch ratio in the formulation	1281:1322	Finally, the stable release of the volatile oil could be optimized by changing the porous starch ratio in the formulation.					
35581209	0	82	theme	volatilization	13:26	arg1	rules					28:32	the volatilization rules	9:32	the volatilization rules of volatile oil	9:48	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	11	83	dep	simple	1779:1784	arg1	easy					1787:1790	easy	1787:1790	easy	1787:1790	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	83	dep	simple	1779:1784	arg1	simple					1779:1784	simple	1779:1784	simple	1779:1784	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	83	dep	simple	1779:1784	arg1	process					1768:1774	the production process	1753:1774	the production process	1753:1774	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	84	theme	application	1817:1827	arg1	value					1829:1833	high application value	1812:1833	high application value	1812:1833	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	1	85	theme	cardiovascular	293:306	arg1	system					267:272	the central nervous system	247:272	the central nervous system	247:272	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	85	theme	cardiovascular	293:306	arg1	system					308:313	cardiovascular system	293:313	cardiovascular system	293:313	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	0	86	theme	oil	95:97	arg1	Study					0:4	Study	0:4	Study of the volatilization rules of volatile oil	0:48	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	0	86	theme	oil	95:97	arg1	effect					76:81	the sustained-release effect	54:81	the sustained-release effect of volatile oil	54:97	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	0	87	theme	oil	46:48	arg1	rules					28:32	the volatilization rules	9:32	the volatilization rules of volatile oil	9:48	Study of the volatilization rules of volatile oil and the sustained-release effect of volatile oil solidified by porous starch.					
35581209	11	88	contain	had	1722:1724	arg2	effect					1741:1746	a slow-release effect	1726:1746	a slow-release effect	1726:1746	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	88	contain	had	1722:1724	arg1	oil					1718:1720	the porous starch-solidified volatile oil	1680:1720	the porous starch-solidified volatile oil	1680:1720	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	1	89	contain	has	213:215	arg1	oil					137:139	Volatile oil	128:139	Volatile oil from traditional Chinese medicine	128:173	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	1	89	contain	has	213:215	arg2	activities					233:242	pharmacological activities	217:242	pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc	217:338	Volatile oil from traditional Chinese medicine has various biological activities and has pharmacological activities in the central nervous system, digestive system, cardiovascular system, respiratory system, etc.					
35581209	10	90	theme	volatile	1610:1617	arg1	oil					1619:1621	the volatile oil	1606:1621	the volatile oil	1606:1621	The physical properties and chemical composition of the volatile oil did not change after curing, indicating that the adsorption of the volatile oil by porous starch was physical adsorption.					
35581209	11	91	theme	production	1757:1766	arg1	easy					1787:1790	easy	1787:1790	easy	1787:1790	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	91	theme	production	1757:1766	arg1	simple					1779:1784	simple	1779:1784	simple	1779:1784	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	11	91	theme	production	1757:1766	arg1	process					1768:1774	the production process	1753:1774	the production process	1753:1774	In this paper, the porous starch-solidified volatile oil had a slow-release effect, and the production process is simple, easy to operate, and has high application value.					
35581209	7	92	theme	portable	1186:1193	arg1	GC-MS					1195:1199	portable GC-MS	1186:1199	portable GC-MS	1186:1199	The solidified volatile oil/porous starch powder was characterized by XRD, TGA and DSC, and the VOCs of the volatile oil before and after solidification were analysed by portable GC-MS.					
35581209	4	93	theme	volatile	595:602	arg1	oil					604:606	a volatile oil	593:606	a volatile oil in the preparation process	593:633	To improve the stability of a volatile oil in the preparation process, its volatilization and stable release must be controlled.					
35508533	10	0	theme	Cell	1521:1524	arg1	studies					1536:1542	Cell viability studies	1521:1542	Cell viability studies	1521:1542	Cell viability studies indicated high biocompatibility of the hydrogel.					
35508533	13	1	theme	novel	1944:1948	arg1	hydrogel					1912:1919	the designed hydrogel	1899:1919	the designed hydrogel	1899:1919	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	13	1	theme	novel	1944:1948	arg1	dressing					1967:1974	a novel attractive wound dressing	1942:1974	a novel attractive wound dressing after further prerequisite assessments	1942:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	13	2	theme	wound	1961:1965	arg1	hydrogel					1912:1919	the designed hydrogel	1899:1919	the designed hydrogel	1899:1919	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	13	2	theme	wound	1961:1965	arg1	dressing					1967:1974	a novel attractive wound dressing	1942:1974	a novel attractive wound dressing after further prerequisite assessments	1942:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	12	3	theme	healing	1775:1781	arg1	rates					1760:1764	higher rates	1753:1764	higher rates of wound healing, re-epithelialization, and collagen deposition	1753:1828	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	10	4	theme	high	1554:1557	arg1	biocompatibility					1559:1574	high biocompatibility	1554:1574	high biocompatibility of the hydrogel	1554:1590	Cell viability studies indicated high biocompatibility of the hydrogel.					
35508533	11	5	theme	hydrogel	1668:1675	arg1	effectiveness					1635:1647	the effectiveness	1631:1647	the effectiveness of the synthesized hydrogel	1631:1675	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	9	6	theme	Scanning	1438:1445	arg1	microscopy					1456:1465	Scanning electron microscopy	1438:1465	Scanning electron microscopy	1438:1465	Scanning electron microscopy showed pore sizes of about 14-198 µm in the hydrogel.					
35508533	6	7	theme	mechanical	958:967	arg1	resistance					969:978	mechanical resistance	958:978	mechanical resistance	958:978	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	12	8	theme	higher	1753:1758	arg1	rates					1760:1764	higher rates	1753:1764	higher rates of wound healing, re-epithelialization, and collagen deposition	1753:1828	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	4	9	theme	Biophysical	617:627	arg1	characterization					629:644	Biophysical characterization	617:644	Biophysical characterization	617:644	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	10	10	theme	hydrogel	1583:1590	arg1	biocompatibility					1559:1574	high biocompatibility	1554:1574	high biocompatibility of the hydrogel	1554:1590	Cell viability studies indicated high biocompatibility of the hydrogel.					
35508533	2	11	theme	healing	297:303	arg1	field					282:286	the field	278:286	the field of wound healing	278:303	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	8	12	theme	sufficient	1417:1426	arg1	porosity					1428:1435	its sufficient porosity	1413:1435	its sufficient porosity	1413:1435	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	2	13	theme	dressing	238:245	arg1	fabrication					202:212	fabrication	202:212	fabrication	202:212	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	2	13	theme	dressing	238:245	arg1	design					191:196	design	191:196	design	191:196	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	2	13	theme	dressing	238:245	arg1	innovation					264:273	an impressive innovation	250:273	an impressive innovation in the field of wound healing	250:303	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	5	14	from	42 °C	852:856	arg1	protein					817:823	the protein	813:823	the protein	813:823	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	14	from	42 °C	852:856	arg1	stable					842:847	stable	842:847	stable	842:847	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	14	from	42 °C	852:856	arg1	temperature					874:884	the maximum temperature	862:884	the maximum temperature of the infected wound	862:906	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	9	15	theme	pore	1474:1477	arg1	sizes					1479:1483	pore sizes	1474:1483	pore sizes of about 14-198 µm in the hydrogel	1474:1518	Scanning electron microscopy showed pore sizes of about 14-198 µm in the hydrogel.					
35508533	2	16	theme	efficacious	220:230	arg1	dressing					238:245	an efficacious wound dressing	217:245	an efficacious wound dressing	217:245	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	13	17	theme	designed	1903:1910	arg1	hydrogel					1912:1919	the designed hydrogel	1899:1919	the designed hydrogel	1899:1919	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	13	17	theme	designed	1903:1910	arg1	dressing					1967:1974	a novel attractive wound dressing	1942:1974	a novel attractive wound dressing after further prerequisite assessments	1942:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	9	18	theme	14-198 µm	1494:1502	arg1	sizes					1479:1483	pore sizes	1474:1483	pore sizes of about 14-198 µm in the hydrogel	1474:1518	Scanning electron microscopy showed pore sizes of about 14-198 µm in the hydrogel.					
35508533	7	19	theme	Gram-negative	1213:1225	arg1	bacteria					1245:1252	Gram-negative and Gram-positive bacteria	1213:1252	Gram-negative and Gram-positive bacteria	1213:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	0	20	theme	new	12:14	arg1	hydrogel					58:65	a new alginate-fibrinogen biomaterial composite hydrogel	10:65	a new alginate-fibrinogen biomaterial composite hydrogel for wound healing	10:83	Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing.					
35508533	6	21	theme	antibacterial	996:1008	arg1	activity					1010:1017	antibacterial activity	996:1017	antibacterial activity	996:1017	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	3	22	theme	wound	321:325	arg1	dressing					327:334	The fabricated wound dressing	306:334	The fabricated wound dressing in this scenario	306:351	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	8	23	theme	water	1320:1324	arg1	amount					1310:1315	a considerable amount	1295:1315	a considerable amount of water	1295:1324	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	8	23	theme	water	1320:1324	arg1	water					1320:1324	water	1320:1324	water	1320:1324	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	5	24	theme	wound	902:906	arg1	protein					817:823	the protein	813:823	the protein	813:823	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	24	theme	wound	902:906	arg1	stable					842:847	stable	842:847	stable	842:847	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	24	theme	wound	902:906	arg1	temperature					874:884	the maximum temperature	862:884	the maximum temperature of the infected wound	862:906	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	7	25	theme	inhibitory	1178:1187	arg1	effect					1189:1194	an inhibitory effect	1175:1194	an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria	1175:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	0	26	theme	composite	48:56	arg1	hydrogel					58:65	a new alginate-fibrinogen biomaterial composite hydrogel	10:65	a new alginate-fibrinogen biomaterial composite hydrogel for wound healing	10:83	Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing.					
35508533	1	27	theme	Wound	86:90	arg1	process					113:119	a complex process	103:119	a complex process	103:119	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	1	27	theme	Wound	86:90	arg1	healing					92:98	Wound healing	86:98	Wound healing	86:98	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	3	28	theme	materials	436:444	arg1	combination					374:384	a combination	372:384	a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent)	372:614	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	3	29	theme	wound	595:599	arg1	healing					601:607	wound healing	595:607	wound healing agent	595:613	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	7	30	theme	Antibacterial	1146:1158	arg1	studies					1160:1166	48 h. Antibacterial studies	1140:1166	48 h. Antibacterial studies	1140:1166	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	1	31	theme	complex	105:111	arg1	process					113:119	a complex process	103:119	a complex process	103:119	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	1	31	theme	complex	105:111	arg1	healing					92:98	Wound healing	86:98	Wound healing	86:98	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	11	32	theme	clot	1714:1717	arg1	formation					1719:1727	blood clot formation	1708:1727	blood clot formation	1708:1727	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	8	33	theme	drug	1382:1385	arg1	oxygenation					1338:1348	oxygenation	1338:1348	oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity	1338:1435	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	8	33	theme	drug	1382:1385	arg1	incorporation					1361:1373	incorporation	1361:1373	oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity	1338:1435	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	13	34	theme	in	1862:1863	arg1	studies					1890:1896	in vitro as well as in vivo studies	1862:1896	in vitro as well as in vivo studies	1862:1896	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	0	35	theme	biomaterial	36:46	arg1	hydrogel					58:65	a new alginate-fibrinogen biomaterial composite hydrogel	10:65	a new alginate-fibrinogen biomaterial composite hydrogel for wound healing	10:83	Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing.					
35508533	3	36	theme	appropriate	393:403	arg1	materials					436:444	the appropriate coagulating and anti-bacterial materials	389:444	the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent)	389:614	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	0	37	theme	wound	71:75	arg1	healing					77:83	wound healing	71:83	wound healing	71:83	Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing.					
35508533	11	38	theme	coagulation	1599:1609	arg1	test					1611:1614	Blood coagulation test	1593:1614	Blood coagulation test	1593:1614	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	3	39	theme	healing	601:607	arg1	agent					609:613	wound healing agent	595:613	wound healing agent	595:613	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	4	40	theme	fibrinogen	677:686	arg1	interaction					662:672	the interaction	658:672	the interaction of fibrinogen and alginate	658:699	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	5	41	dep	stable	842:847	arg1	protein					817:823	the protein	813:823	the protein	813:823	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	41	dep	stable	842:847	arg1	stable					842:847	stable	842:847	stable	842:847	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	41	dep	stable	842:847	arg1	temperature					874:884	the maximum temperature	862:884	the maximum temperature of the infected wound	862:906	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	13	42	theme	further	1982:1988	arg1	assessments					2003:2013	further prerequisite assessments	1982:2013	further prerequisite assessments	1982:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	12	43	theme	collagen	1810:1817	arg1	deposition					1819:1828	collagen deposition	1810:1828	collagen deposition	1810:1828	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	10	44	theme	viability	1526:1534	arg1	studies					1536:1542	Cell viability studies	1521:1542	Cell viability studies	1521:1542	Cell viability studies indicated high biocompatibility of the hydrogel.					
35508533	11	45	theme	synthesized	1656:1666	arg1	hydrogel					1668:1675	the synthesized hydrogel	1652:1675	the synthesized hydrogel	1652:1675	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	7	46	theme	slow	1106:1109	arg1	release					1111:1117	a slow release	1104:1117	a slow release for the nisin during 48 h. Antibacterial studies	1104:1166	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	3	47	theme	anti-bacterial	496:509	arg1	agent					511:515	anti-bacterial agent	496:515	anti-bacterial agent	496:515	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	12	48	theme	wound	1769:1773	arg1	healing					1775:1781	wound healing	1769:1781	wound healing	1769:1781	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	7	49	theme	Gram-positive	1231:1243	arg1	bacteria					1245:1252	Gram-negative and Gram-positive bacteria	1213:1252	Gram-negative and Gram-positive bacteria	1213:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	13	50	theme	attractive	1950:1959	arg1	hydrogel					1912:1919	the designed hydrogel	1899:1919	the designed hydrogel	1899:1919	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	13	50	theme	attractive	1950:1959	arg1	dressing					1967:1974	a novel attractive wound dressing	1942:1974	a novel attractive wound dressing after further prerequisite assessments	1942:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	2	51	theme	wound	291:295	arg1	healing					297:303	wound healing	291:303	wound healing	291:303	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	5	52	theme	infected	893:900	arg1	wound					902:906	the infected wound	889:906	the infected wound	889:906	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	3	53	theme	ethylenediaminetetraacetic	519:544	arg1	acid					546:549	ethylenediaminetetraacetic acid	519:549	ethylenediaminetetraacetic acid (as anti-bacterial agent)	519:575	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	7	54	dep	showed	1097:1102	arg1	showed					1168:1173	showed	1168:1173	showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria	1097:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	12	55	dep	In	1730:1731	arg1	vivo					1733:1736	vivo	1733:1736	vivo	1733:1736	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	5	56	theme	maximum	866:872	arg1	protein					817:823	the protein	813:823	the protein	813:823	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	56	theme	maximum	866:872	arg1	stable					842:847	stable	842:847	stable	842:847	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	5	56	theme	maximum	866:872	arg1	temperature					874:884	the maximum temperature	862:884	the maximum temperature of the infected wound	862:906	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	9	57	from	sizes	1479:1483	arg1	hydrogel					1511:1518	the hydrogel	1507:1518	the hydrogel	1507:1518	Scanning electron microscopy showed pore sizes of about 14-198 µm in the hydrogel.					
35508533	13	58	dep	in	1882:1883	arg1	vivo					1885:1888	vivo	1885:1888	vivo	1885:1888	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	3	59	theme	anti-bacterial	555:568	arg1	agent					570:574	anti-bacterial agent	555:574	anti-bacterial agent	555:574	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	9	60	theme	electron	1447:1454	arg1	microscopy					1456:1465	Scanning electron microscopy	1438:1465	Scanning electron microscopy	1438:1465	Scanning electron microscopy showed pore sizes of about 14-198 µm in the hydrogel.					
35508533	7	61	from	effect	1189:1194	arg1	growth					1203:1208	the growth	1199:1208	the growth of Gram-negative and Gram-positive bacteria	1199:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	2	62	theme	wound	232:236	arg1	dressing					238:245	an efficacious wound dressing	217:245	an efficacious wound dressing	217:245	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	6	63	theme	hydrogel	931:938	arg1	release					987:993	nisin release	981:993	nisin release	981:993	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	properties					913:922	The properties	909:922	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation	909:1068	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	swelling					948:955	swelling	948:955	swelling	948:955	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	porosity					1038:1045	gel porosity	1034:1045	gel porosity	1034:1045	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	resistance					969:978	mechanical resistance	958:978	mechanical resistance	958:978	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	activity					1010:1017	antibacterial activity	996:1017	antibacterial activity	996:1017	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	cytotoxicity					1020:1031	cytotoxicity	1020:1031	cytotoxicity	1020:1031	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	6	63	theme	hydrogel	931:938	arg1	coagulation					1058:1068	blood coagulation	1052:1068	blood coagulation	1052:1068	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	3	64	theme	fabricated	310:319	arg1	dressing					327:334	The fabricated wound dressing	306:334	The fabricated wound dressing in this scenario	306:351	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	7	65	theme	48 h.	1140:1144	arg1	studies					1160:1166	48 h. Antibacterial studies	1140:1166	48 h. Antibacterial studies	1140:1166	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	3	66	from	dressing	327:334	arg1	scenario					344:351	this scenario	339:351	this scenario	339:351	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	1	67	theme	rapid	125:129	arg1	healing					131:137	rapid healing	125:137	rapid healing	125:137	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	4	68	theme	minor	721:725	arg1	changes					727:733	minor changes	721:733	minor changes in the secondary structure of the protein	721:775	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	2	69	theme	impressive	253:262	arg1	fabrication					202:212	fabrication	202:212	fabrication	202:212	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	2	69	theme	impressive	253:262	arg1	design					191:196	design	191:196	design	191:196	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	2	69	theme	impressive	253:262	arg1	innovation					264:273	an impressive innovation	250:273	an impressive innovation in the field of wound healing	250:303	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	12	70	theme	In	1730:1731	arg1	studies					1738:1744	In vivo studies	1730:1744	In vivo studies	1730:1744	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	8	71	theme	considerable	1297:1308	arg1	amount					1310:1315	a considerable amount	1295:1315	a considerable amount of water	1295:1324	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	8	71	theme	considerable	1297:1308	arg1	water					1320:1324	water	1320:1324	water	1320:1324	The hydrogel was also capable to absorb a considerable amount of water and provide oxygenation as well as incorporation of the drug into its structure due to its sufficient porosity.					
35508533	13	72	theme	in	1882:1883	arg1	studies					1890:1896	in vitro as well as in vivo studies	1862:1896	in vitro as well as in vivo studies	1862:1896	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	1	73	theme	proper	154:159	arg1	micro-environment					161:177	a proper micro-environment	152:177	a proper micro-environment	152:177	Wound healing is a complex process and rapid healing necessitates a proper micro-environment.					
35508533	4	74	theme	alginate	692:699	arg1	interaction					662:672	the interaction	658:672	the interaction of fibrinogen and alginate	658:699	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	13	75	from	studies	1890:1896	arg1	findings					1848:1855	the findings	1844:1855	the findings from in vitro as well as in vivo studies	1844:1896	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	6	76	theme	nisin	981:985	arg1	release					987:993	nisin release	981:993	nisin release	981:993	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	4	77	theme	protein	769:775	arg1	structure					752:760	the secondary structure	738:760	the secondary structure of the protein	738:775	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	6	78	theme	blood	1052:1056	arg1	coagulation					1058:1068	blood coagulation	1052:1068	blood coagulation	1052:1068	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	0	79	theme	alginate-fibrinogen	16:34	arg1	hydrogel					58:65	a new alginate-fibrinogen biomaterial composite hydrogel	10:65	a new alginate-fibrinogen biomaterial composite hydrogel for wound healing	10:83	Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing.					
35508533	13	80	dep	in	1862:1863	arg1	vitro					1865:1869	vitro	1865:1869	vitro	1865:1869	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
35508533	11	81	theme	blood	1708:1712	arg1	formation					1719:1727	blood clot formation	1708:1727	blood clot formation	1708:1727	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	4	82	theme	secondary	742:750	arg1	structure					752:760	the secondary structure	738:760	the secondary structure of the protein	738:775	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	5	83	theme	Conformational	778:791	arg1	studies					793:799	Conformational studies	778:799	Conformational studies	778:799	Conformational studies showed that the protein was structurally stable at 42 °C, is the maximum temperature of the infected wound.					
35508533	2	84	from	innovation	264:273	arg1	field					282:286	the field	278:286	the field of wound healing	278:303	Therefore, design and fabrication of an efficacious wound dressing is an impressive innovation in the field of wound healing.					
35508533	6	85	theme	gel	1034:1036	arg1	porosity					1038:1045	gel porosity	1034:1045	gel porosity	1034:1045	The properties of the hydrogel such as swelling, mechanical resistance, nisin release, antibacterial activity, cytotoxicity, gel porosity, and blood coagulation were assessed.					
35508533	3	86	theme	anti-bacterial	421:434	arg1	materials					436:444	the appropriate coagulating and anti-bacterial materials	389:444	the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent)	389:614	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	11	87	theme	Blood	1593:1597	arg1	test					1611:1614	Blood coagulation test	1593:1614	Blood coagulation test	1593:1614	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	3	88	theme	coagulating	466:476	arg1	agent					478:482	coagulating agent	466:482	coagulating agent	466:482	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	12	89	theme	deposition	1819:1828	arg1	rates					1760:1764	higher rates	1753:1764	higher rates of wound healing, re-epithelialization, and collagen deposition	1753:1828	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	3	90	theme	coagulating	405:415	arg1	materials					436:444	the appropriate coagulating and anti-bacterial materials	389:444	the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent)	389:614	The fabricated wound dressing in this scenario was designed using a combination of the appropriate coagulating and anti-bacterial materials like fibrinogen (as coagulating agent), nisin (as anti-bacterial agent), ethylenediaminetetraacetic acid (as anti-bacterial agent), and alginate (as wound healing agent).					
35508533	4	91	from	changes	727:733	arg1	structure					752:760	the secondary structure	738:760	the secondary structure of the protein	738:775	Biophysical characterization showed that the interaction of fibrinogen and alginate was associated with minor changes in the secondary structure of the protein.					
35508533	11	92	theme	formation	1719:1727	arg1	process					1697:1703	the process	1693:1703	the process of blood clot formation	1693:1727	Blood coagulation test also confirmed the effectiveness of the synthesized hydrogel in accelerating the process of blood clot formation.					
35508533	12	93	theme	re-epithelialization	1784:1803	arg1	rates					1760:1764	higher rates	1753:1764	higher rates of wound healing, re-epithelialization, and collagen deposition	1753:1828	In vivo studies showed higher rates of wound healing, re-epithelialization, and collagen deposition.					
35508533	7	94	theme	bacteria	1245:1252	arg1	growth					1203:1208	the growth	1199:1208	the growth of Gram-negative and Gram-positive bacteria	1199:1252	The results showed a slow release for the nisin during 48 h. Antibacterial studies showed an inhibitory effect on the growth of Gram-negative and Gram-positive bacteria.					
35508533	13	95	theme	prerequisite	1990:2001	arg1	assessments					2003:2013	further prerequisite assessments	1982:2013	further prerequisite assessments	1982:2013	According to the findings from in vitro as well as in vivo studies, the designed hydrogel can be considered as a novel attractive wound dressing after further prerequisite assessments.					
36220411	0	0	theme	green	109:113	arg1	removal					88:94	highly efficient removal	71:94	highly efficient removal of malachite green from water	71:124	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	3	1	theme	Alginate/CA-sawdust/Fe3O4	452:476	arg1	composite					441:449	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	3	1	theme	Alginate/CA-sawdust/Fe3O4	452:476	arg1	beads					478:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	7	2	theme	removal	958:964	arg1	mechanisms					966:975	probable removal mechanisms	949:975	probable removal mechanisms	949:975	Moreover, both film and intraparticle diffusion models were found to be probable removal mechanisms.					
36220411	0	3	theme	malachite	99:107	arg1	green					109:113	malachite green	99:113	malachite green	99:113	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	4	4	theme	Easy	551:554	arg1	properties					644:653	two significant properties	628:653	two significant properties of this bio-sorbent	628:673	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	4	4	theme	Easy	551:554	arg1	separation					556:565	Easy separation	551:565	Easy separation under a magnetic field and reusability	551:604	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	1	5	theme	striking	183:190	arg1	features					192:199	striking features	183:199	striking features for pollutant uptake	183:220	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	5	6	theme	MG	702:703	arg1	percentage					688:697	The removal percentage	676:697	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads	676:741	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads was calculated to be 90-95 %.					
36220411	5	6	theme	MG	702:703	arg1	%					770:770	90-95 %	764:770	90-95 %	764:770	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads was calculated to be 90-95 %.					
36220411	3	7	theme	malachite	529:537	arg1	green					539:543	cationic malachite green	520:543	cationic malachite green (MG)	520:548	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	3	7	theme	malachite	529:537	arg1	MG					546:547	MG	546:547	MG	546:547	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	1	8	with	by-product	140:149	arg1	features					192:199	striking features	183:199	striking features for pollutant uptake	183:220	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	2	9	theme	composite	294:302	arg1	beads					304:308	sustainable magnetic alginate composite beads	264:308	sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles	264:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	10	from	time	237:240	arg1	study					257:261	the current study	245:261	the current study	245:261	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	6	11	theme	kinetic	861:867	arg1	models					869:874	nonlinear pseudo-first-order kinetic models	832:874	nonlinear pseudo-first-order kinetic models	832:874	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	2	12	theme	alginate	285:292	arg1	beads					304:308	sustainable magnetic alginate composite beads	264:308	sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles	264:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	7	13	theme	diffusion	915:923	arg1	models					925:930	both film and intraparticle diffusion models	887:930	both film and intraparticle diffusion models	887:930	Moreover, both film and intraparticle diffusion models were found to be probable removal mechanisms.					
36220411	0	14	theme	alginate/citric	12:26	arg1	acid-sawdust/Fe3O4					28:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4	0:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4	0:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	6	15	theme	pseudo-first-order	842:859	arg1	models					869:874	nonlinear pseudo-first-order kinetic models	832:874	nonlinear pseudo-first-order kinetic models	832:874	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	1	16	theme	pollutant	205:213	arg1	uptake					215:220	pollutant uptake	205:220	pollutant uptake	205:220	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	0	17	theme	Bio-sorbent	0:10	arg1	acid-sawdust/Fe3O4					28:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4	0:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4	0:45	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	5	18	theme	removal	680:686	arg1	percentage					688:697	The removal percentage	676:697	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads	676:741	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads was calculated to be 90-95 %.					
36220411	5	18	theme	removal	680:686	arg1	%					770:770	90-95 %	764:770	90-95 %	764:770	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads was calculated to be 90-95 %.					
36220411	6	19	theme	nonlinear	832:840	arg1	models					869:874	nonlinear pseudo-first-order kinetic models	832:874	nonlinear pseudo-first-order kinetic models	832:874	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	2	20	theme	acid-modified	328:340	arg1	CA-sawdust					351:360	CA-sawdust	351:360	CA-sawdust	351:360	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	20	theme	acid-modified	328:340	arg1	sawdust					342:348	citric acid-modified sawdust	321:348	citric acid-modified sawdust (CA-sawdust)	321:361	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	20	theme	acid-modified	328:340	arg1	bio-waste					368:376	a bio-waste	366:376	a bio-waste	366:376	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	20	theme	acid-modified	328:340	arg1	nanoparticles					388:400	Fe3O4 nanoparticles	382:400	Fe3O4 nanoparticles	382:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	7	21	theme	intraparticle	901:913	arg1	models					925:930	both film and intraparticle diffusion models	887:930	both film and intraparticle diffusion models	887:930	Moreover, both film and intraparticle diffusion models were found to be probable removal mechanisms.					
36220411	2	22	theme	citric	321:326	arg1	CA-sawdust					351:360	CA-sawdust	351:360	CA-sawdust	351:360	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	22	theme	citric	321:326	arg1	sawdust					342:348	citric acid-modified sawdust	321:348	citric acid-modified sawdust (CA-sawdust)	321:361	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	22	theme	citric	321:326	arg1	bio-waste					368:376	a bio-waste	366:376	a bio-waste	366:376	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	22	theme	citric	321:326	arg1	nanoparticles					388:400	Fe3O4 nanoparticles	382:400	Fe3O4 nanoparticles	382:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	4	23	theme	bio-sorbent	663:673	arg1	properties					644:653	two significant properties	628:653	two significant properties of this bio-sorbent	628:673	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	4	23	theme	bio-sorbent	663:673	arg1	separation					556:565	Easy separation	551:565	Easy separation under a magnetic field and reusability	551:604	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	2	24	contain	containing	310:319	arg1	beads					304:308	sustainable magnetic alginate composite beads	264:308	sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles	264:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	24	contain	containing	310:319	arg2	CA-sawdust					351:360	CA-sawdust	351:360	CA-sawdust	351:360	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	24	contain	containing	310:319	arg2	sawdust					342:348	citric acid-modified sawdust	321:348	citric acid-modified sawdust (CA-sawdust)	321:361	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	24	contain	containing	310:319	arg2	bio-waste					368:376	a bio-waste	366:376	a bio-waste	366:376	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	24	contain	containing	310:319	arg2	nanoparticles					388:400	Fe3O4 nanoparticles	382:400	Fe3O4 nanoparticles	382:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	25	theme	current	249:255	arg1	study					257:261	the current study	245:261	the current study	245:261	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	7	26	theme	film	892:895	arg1	models					925:930	both film and intraparticle diffusion models	887:930	both film and intraparticle diffusion models	887:930	Moreover, both film and intraparticle diffusion models were found to be probable removal mechanisms.					
36220411	0	27	theme	efficient	78:86	arg1	removal					88:94	highly efficient removal	71:94	highly efficient removal of malachite green from water	71:124	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	5	28	theme	alginate/CA-sawdust/Fe3O4	711:735	arg1	beads					737:741	alginate/CA-sawdust/Fe3O4 beads	711:741	alginate/CA-sawdust/Fe3O4 beads	711:741	The removal percentage of MG using alginate/CA-sawdust/Fe3O4 beads was calculated to be 90-95 %.					
36220411	6	29	with	well-described	790:803	arg1	models					869:874	nonlinear pseudo-first-order kinetic models	832:874	nonlinear pseudo-first-order kinetic models	832:874	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	6	29	with	well-described	790:803	arg1	isotherm					819:826	Langmuir isotherm	810:826	Langmuir isotherm	810:826	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	6	30	theme	Langmuir	810:817	arg1	isotherm					819:826	Langmuir isotherm	810:826	Langmuir isotherm	810:826	This process was well-described with Langmuir isotherm and nonlinear pseudo-first-order kinetic models.					
36220411	3	31	theme	eco-friendly	428:439	arg1	composite					441:449	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	3	31	theme	eco-friendly	428:439	arg1	beads					478:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	4	32	theme	magnetic	575:582	arg1	field					584:588	a magnetic field	573:588	a magnetic field	573:588	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	2	33	theme	first	231:235	arg1	time					237:240	the first time	227:240	the first time in the current study	227:261	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	34	theme	magnetic	276:283	arg1	beads					304:308	sustainable magnetic alginate composite beads	264:308	sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles	264:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	3	35	theme	cationic	520:527	arg1	green					539:543	cationic malachite green	520:543	cationic malachite green (MG)	520:548	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	3	35	theme	cationic	520:527	arg1	MG					546:547	MG	546:547	MG	546:547	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	0	36	from	water	120:124	arg1	removal					88:94	highly efficient removal	71:94	highly efficient removal of malachite green from water	71:124	Bio-sorbent alginate/citric acid-sawdust/Fe3O4 nanocomposite beads for highly efficient removal of malachite green from water.					
36220411	2	37	theme	sustainable	264:274	arg1	beads					304:308	sustainable magnetic alginate composite beads	264:308	sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles	264:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	1	38	theme	industries	167:176	arg1	by-product					140:149	a by-product	138:149	a by-product of wood-related industries with striking features for pollutant uptake	138:220	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	1	38	theme	industries	167:176	arg1	Sawdust					127:133	Sawdust	127:133	Sawdust	127:133	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	4	39	theme	significant	632:642	arg1	properties					644:653	two significant properties	628:653	two significant properties of this bio-sorbent	628:673	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	4	39	theme	significant	632:642	arg1	separation					556:565	Easy separation	551:565	Easy separation under a magnetic field and reusability	551:604	Easy separation under a magnetic field and reusability could be mentioned as two significant properties of this bio-sorbent.					
36220411	1	40	theme	wood-related	154:165	arg1	industries					167:176	wood-related industries	154:176	wood-related industries	154:176	Sawdust is a by-product of wood-related industries with striking features for pollutant uptake.					
36220411	3	41	theme	novel	422:426	arg1	composite					441:449	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads)	417:483	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	3	41	theme	novel	422:426	arg1	beads					478:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	Alginate/CA-sawdust/Fe3O4 beads	452:482	This novel eco-friendly composite (Alginate/CA-sawdust/Fe3O4 beads) was successfully applied to remove cationic malachite green (MG).					
36220411	2	42	theme	Fe3O4	382:386	arg1	sawdust					342:348	citric acid-modified sawdust	321:348	citric acid-modified sawdust (CA-sawdust)	321:361	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	2	42	theme	Fe3O4	382:386	arg1	nanoparticles					388:400	Fe3O4 nanoparticles	382:400	Fe3O4 nanoparticles	382:400	For the first time in the current study, sustainable magnetic alginate composite beads containing citric acid-modified sawdust (CA-sawdust) as a bio-waste and Fe3O4 nanoparticles were designed.					
36220411	7	43	theme	probable	949:956	arg1	mechanisms					966:975	probable removal mechanisms	949:975	probable removal mechanisms	949:975	Moreover, both film and intraparticle diffusion models were found to be probable removal mechanisms.					
36156387	0	0	theme	food	73:76	arg1	components					78:87	food components	73:87	food components	73:87	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	9	1	theme	starch-rich	1326:1336	arg1	foods					1338:1342	sugar and starch-rich foods	1316:1342	foods	1338:1342	Moreover, there were exponential relationships between Tg ' or Tm ' values and MW for sugar and starch-rich foods taken together.					
36156387	9	2	theme	exponential	1251:1261	arg1	relationships					1263:1275	exponential relationships	1251:1275	exponential relationships between Tg ' or Tm ' values and MW for sugar and starch-rich foods taken together	1251:1357	Moreover, there were exponential relationships between Tg ' or Tm ' values and MW for sugar and starch-rich foods taken together.					
36156387	2	3	theme	transition	318:327	arg1	Tg					342:343	Tg '	342:345	Tg '	342:345	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	3	theme	transition	318:327	arg1	temperature					329:339	the glass transition temperature	308:339	the glass transition temperature (Tg ')	308:346	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	0	4	from	transitions	6:16	arg1	systems					28:34	frozen systems	21:34	frozen systems	21:34	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	7	5	dep	Tg	905:906	arg1	The					901:903	The	901:903	The	901:903	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	1	6	theme	storage	138:144	arg1	life					146:149	the storage life	134:149	the storage life of foods with high water content	134:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	12	7	theme	foods	1726:1730	arg1	stability					1706:1714	the stability	1702:1714	the stability of frozen foods	1702:1730	Therefore, storage below Tg ' is not the only factor for predicting the stability of frozen foods.					
36156387	3	8	theme	system	557:562	arg1	composition					535:545	the chemical composition	522:545	the chemical composition of frozen system	522:562	The value of Tg ', Tm ', and Xs ' depends on the chemical composition of frozen system.					
36156387	2	9	theme	glass	312:316	arg1	Tg					342:343	Tg '	342:345	Tg '	342:345	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	9	theme	glass	312:316	arg1	temperature					329:339	the glass transition temperature	308:339	the glass transition temperature (Tg ')	308:346	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	10	theme	maximum	252:258	arg1	concentration					267:279	maximum freeze concentration	252:279	maximum freeze concentration	252:279	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	4	11	theme	deteriorative	590:602	arg1	reactions					604:612	deteriorative reactions	590:612	deteriorative reactions	590:612	Below Tg ', the rates of deteriorative reactions are significantly reduced.					
36156387	0	12	theme	components	78:87	arg1	weight					63:68	molecular weight	53:68	molecular weight of food components	53:87	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	3	13	theme	frozen	550:555	arg1	system					557:562	frozen system	550:562	frozen system	550:562	The value of Tg ', Tm ', and Xs ' depends on the chemical composition of frozen system.					
36156387	11	14	theme	storage	1592:1598	arg1	temperature					1600:1610	storage temperature	1592:1610	storage temperature	1592:1610	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	5	15	theme	frozen	705:710	arg1	sugars					730:735	sugars	730:735	sugars	730:735	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	15	theme	frozen	705:710	arg1	systems					712:718	different frozen systems	695:718	different frozen systems including sugars, starches, proteins, and food	695:765	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	15	theme	frozen	705:710	arg1	proteins					748:755	proteins	748:755	proteins	748:755	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	15	theme	frozen	705:710	arg1	food					762:765	food	762:765	food	762:765	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	15	theme	frozen	705:710	arg1	starches					738:745	starches	738:745	starches	738:745	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	7	16	theme	most	922:925	arg1	starches					927:934	most starches	922:934	most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%)	922:983	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	17	theme	sugar-rich	1101:1110	arg1	foods					1112:1116	sugar-rich foods	1101:1116	sugar-rich foods	1101:1116	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	18	theme	%	1050:1050	arg1	%					1059:1059	25.0% to 52.9%	1046:1059	25.0% to 52.9%	1046:1059	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	19	theme	protein-rich	994:1005	arg1	foods					1007:1011	some protein-rich foods	989:1011	some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%)	989:1060	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	11	20	theme	frozen	1571:1576	arg1	foods					1578:1582	frozen foods	1571:1582	frozen foods	1571:1582	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	7	21	theme	foods	1007:1011	arg1	Tg					905:906	Tg '	905:908	Tg '	905:908	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	21	theme	foods	1007:1011	arg1	Tm					914:915	Tm '	914:917	Tm '	914:917	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	22	dep	%	1040:1040	arg1	to					1033:1034	to	1033:1034	to	1033:1034	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	2	23	theme	solids	420:425	arg1	concentration					403:415	concentration	403:415	concentration of solids (Xs ') in the maximum-freeze-concentrated matrix	403:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	23	theme	solids	420:425	arg1	point					353:357	end point	349:357	end point of freezing or onset of melting (Tm ')	349:396	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	23	theme	solids	420:425	arg1	Tg					342:343	Tg '	342:345	Tg '	342:345	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	23	theme	solids	420:425	arg1	temperature					329:339	the glass transition temperature	308:339	the glass transition temperature (Tg ')	308:346	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	23	theme	solids	420:425	arg1	Xs					428:429	Xs '	428:431	Xs '	428:431	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	5	24	theme	systems	712:718	arg1	Tg					671:672	Tg '	671:674	Tg '	671:674	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	7	25	dep	%	982:982	arg1	to					975:976	to	975:976	to	975:976	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	6	26	theme	molecular	859:867	arg1	MW					877:878	MW	877:878	MW	877:878	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	6	26	theme	molecular	859:867	arg1	weight					869:874	molecular weight	859:874	molecular weight (MW) of food components	859:898	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	11	27	theme	other	1492:1496	arg1	studies					1498:1504	other studies	1492:1504	other studies	1492:1504	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	2	28	theme	melting	383:389	arg1	onset					374:378	onset	374:378	onset of melting (Tm ')	374:396	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	28	theme	melting	383:389	arg1	freezing					362:369	freezing	362:369	freezing	362:369	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	6	29	from	trends	799:804	arg1	data					823:826	Tg ' and Tm ' data	809:826	Tg ' and Tm ' data of food	809:834	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	10	30	theme	frozen	1384:1389	arg1	storage					1391:1397	frozen storage	1384:1397	frozen storage below Tg '	1384:1408	Some studies found that frozen storage below Tg ' maintains the higher quality of food that was achieved by fast freezing.					
36156387	7	31	dep	starches	927:934	arg1	increased					937:945	increased	937:945	increased by 2.46% to 87.3% and 10.8% to 85.0%	937:982	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	1	32	theme	foods	154:158	arg1	life					146:149	the storage life	134:149	the storage life of foods with high water content	134:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	0	33	theme	Glass	0:4	arg1	transitions					6:16	Glass transitions	0:16	Glass transitions in frozen systems	0:34	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	7	34	dep	%	963:963	arg1	to					956:957	to	956:957	to	956:957	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	6	35	theme	food	831:834	arg1	data					823:826	Tg ' and Tm ' data	809:826	Tg ' and Tm ' data of food	809:834	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	0	36	theme	frozen	21:26	arg1	systems					28:34	frozen systems	21:34	frozen systems	21:34	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	12	37	theme	frozen	1719:1724	arg1	foods					1726:1730	frozen foods	1719:1730	frozen foods	1719:1730	Therefore, storage below Tg ' is not the only factor for predicting the stability of frozen foods.					
36156387	2	38	theme	maximum-freeze-concentrated	441:467	arg1	matrix					469:474	the maximum-freeze-concentrated matrix	437:474	the maximum-freeze-concentrated matrix	437:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	39	from	temperature	329:339	arg1	matrix					469:474	the maximum-freeze-concentrated matrix	437:474	the maximum-freeze-concentrated matrix	437:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	40	theme	concentration	267:279	arg1	condition					239:247	a condition	237:247	a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix	237:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	11	41	theme	significant	1530:1540	arg1	difference					1542:1551	no significant difference	1527:1551	no significant difference in the quality of frozen foods between storage temperature	1527:1610	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	2	42	theme	freezing	362:369	arg1	concentration					403:415	concentration	403:415	concentration of solids (Xs ') in the maximum-freeze-concentrated matrix	403:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	42	theme	freezing	362:369	arg1	point					353:357	end point	349:357	end point of freezing or onset of melting (Tm ')	349:396	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	42	theme	freezing	362:369	arg1	Tg					342:343	Tg '	342:345	Tg '	342:345	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	42	theme	freezing	362:369	arg1	temperature					329:339	the glass transition temperature	308:339	the glass transition temperature (Tg ')	308:346	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	42	theme	freezing	362:369	arg1	Xs					428:429	Xs '	428:431	Xs '	428:431	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	43	theme	freeze	260:265	arg1	concentration					267:279	maximum freeze concentration	252:279	maximum freeze concentration	252:279	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	1	44	theme	water	170:174	arg1	content					176:182	high water content	165:182	high water content	165:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	8	45	theme	solids	1177:1182	arg1	MW					1171:1172	MW	1171:1172	MW of solids	1171:1182	Both Tg ' and Tm ' values increased with increasing MW of solids in frozen food, reaching an asymptotic value.					
36156387	7	46	dep	foods	1007:1011	arg1	increased					1014:1022	increased	1014:1022	increased by 5.00% to 53.4% and 25.0% to 52.9%	1014:1059	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	11	47	from	difference	1542:1551	arg1	quality					1560:1566	the quality	1556:1566	the quality of frozen foods	1556:1582	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	7	48	theme	foods	1112:1116	arg1	values					1091:1096	the maximum values	1079:1096	the maximum values of sugar-rich foods	1079:1116	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	10	49	theme	food	1442:1445	arg1	quality					1431:1437	the higher quality	1420:1437	the higher quality of food that was achieved by fast freezing	1420:1480	Some studies found that frozen storage below Tg ' maintains the higher quality of food that was achieved by fast freezing.					
36156387	2	50	theme	onset	374:378	arg1	concentration					403:415	concentration	403:415	concentration of solids (Xs ') in the maximum-freeze-concentrated matrix	403:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	50	theme	onset	374:378	arg1	point					353:357	end point	349:357	end point of freezing or onset of melting (Tm ')	349:396	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	50	theme	onset	374:378	arg1	Tg					342:343	Tg '	342:345	Tg '	342:345	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	50	theme	onset	374:378	arg1	temperature					329:339	the glass transition temperature	308:339	the glass transition temperature (Tg ')	308:346	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	50	theme	onset	374:378	arg1	Xs					428:429	Xs '	428:431	Xs '	428:431	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	51	theme	end	349:351	arg1	point					353:357	end point	349:357	end point of freezing or onset of melting (Tm ')	349:396	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	7	52	dep	%	1059:1059	arg1	to					1052:1053	to	1052:1053	to	1052:1053	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	9	53	theme	sugar	1316:1320	arg1	foods					1338:1342	sugar and starch-rich foods	1316:1342	foods	1338:1342	Moreover, there were exponential relationships between Tg ' or Tm ' values and MW for sugar and starch-rich foods taken together.					
36156387	2	54	from	concentration	403:415	arg1	matrix					469:474	the maximum-freeze-concentrated matrix	437:474	the maximum-freeze-concentrated matrix	437:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	2	55	theme	suitable	191:198	arg1	rates					208:212	suitable cooling rates	191:212	suitable cooling rates	191:212	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	7	56	theme	maximum	1083:1089	arg1	values					1091:1096	the maximum values	1079:1096	the maximum values of sugar-rich foods	1079:1116	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	6	57	theme	components	889:898	arg1	MW					877:878	MW	877:878	MW	877:878	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	6	57	theme	components	889:898	arg1	weight					869:874	molecular weight	859:874	molecular weight (MW) of food components	859:898	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	7	58	theme	starches	927:934	arg1	Tg					905:906	Tg '	905:908	Tg '	905:908	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	58	theme	starches	927:934	arg1	Tm					914:915	Tm '	914:917	Tm '	914:917	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	6	59	theme	food	884:887	arg1	components					889:898	food components	884:898	food components	884:898	The trends in Tg ' and Tm ' data of food are investigated using molecular weight (MW) of food components.					
36156387	1	60	with	life	146:149	arg1	content					176:182	high water content	165:182	high water content	165:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	10	61	theme	fast	1468:1471	arg1	freezing					1473:1480	fast freezing	1468:1480	fast freezing	1468:1480	Some studies found that frozen storage below Tg ' maintains the higher quality of food that was achieved by fast freezing.					
36156387	2	62	theme	cooling	200:206	arg1	rates					208:212	suitable cooling rates	191:212	suitable cooling rates	191:212	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	1	63	theme	used	115:118	arg1	way					120:122	a frequently used way	102:122	a frequently used way to expand the storage life of foods with high water content	102:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	1	63	theme	used	115:118	arg1	Freezing					90:97	Freezing	90:97	Freezing	90:97	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	4	64	theme	reactions	604:612	arg1	rates					581:585	the rates	577:585	the rates of deteriorative reactions	577:612	Below Tg ', the rates of deteriorative reactions are significantly reduced.					
36156387	8	65	theme	asymptotic	1212:1221	arg1	value					1223:1227	an asymptotic value	1209:1227	an asymptotic value	1209:1227	Both Tg ' and Tm ' values increased with increasing MW of solids in frozen food, reaching an asymptotic value.					
36156387	11	66	theme	foods	1578:1582	arg1	quality					1560:1566	the quality	1556:1566	the quality of frozen foods	1556:1582	However, other studies found that there was no significant difference in the quality of frozen foods between storage temperature below and above Tg '.					
36156387	10	67	theme	higher	1424:1429	arg1	quality					1431:1437	the higher quality	1420:1437	the higher quality of food that was achieved by fast freezing	1420:1480	Some studies found that frozen storage below Tg ' maintains the higher quality of food that was achieved by fast freezing.					
36156387	2	68	from	point	353:357	arg1	matrix					469:474	the maximum-freeze-concentrated matrix	437:474	the maximum-freeze-concentrated matrix	437:474	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	7	69	theme	%	973:973	arg1	%					982:982	10.8% to 85.0%	969:982	10.8% to 85.0%	969:982	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	7	70	theme	%	954:954	arg1	%					963:963	2.46% to 87.3%	950:963	2.46% to 87.3%	950:963	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	3	71	theme	chemical	526:533	arg1	composition					535:545	the chemical composition	522:545	the chemical composition of frozen system	522:562	The value of Tg ', Tm ', and Xs ' depends on the chemical composition of frozen system.					
36156387	2	72	theme	frozen	215:220	arg1	systems					222:228	frozen systems	215:228	frozen systems	215:228	Under suitable cooling rates, frozen systems attain a condition of maximum freeze concentration, which is characterized by the glass transition temperature (Tg '), end point of freezing or onset of melting (Tm '), and concentration of solids (Xs ') in the maximum-freeze-concentrated matrix.					
36156387	1	73	theme	high	165:168	arg1	content					176:182	high water content	165:182	high water content	165:182	Freezing is a frequently used way to expand the storage life of foods with high water content.					
36156387	12	74	theme	only	1675:1678	arg1	factor					1680:1685	the only factor	1671:1685	the only factor for predicting the stability of frozen foods	1671:1730	Therefore, storage below Tg ' is not the only factor for predicting the stability of frozen foods.					
36156387	12	74	theme	only	1675:1678	arg1	storage					1645:1651	storage	1645:1651	storage below Tg '	1645:1662	Therefore, storage below Tg ' is not the only factor for predicting the stability of frozen foods.					
36156387	0	75	theme	molecular	53:61	arg1	weight					63:68	molecular weight	53:68	molecular weight of food components	53:87	Glass transitions in frozen systems as influenced by molecular weight of food components.					
36156387	7	76	theme	%	1031:1031	arg1	%					1040:1040	5.00% to 53.4%	1027:1040	5.00% to 53.4%	1027:1040	The Tg ' and Tm ' of most starches (increased by 2.46% to 87.3% and 10.8% to 85.0%) and some protein-rich foods (increased by 5.00% to 53.4% and 25.0% to 52.9%) were higher than the maximum values of sugar-rich foods.					
36156387	5	77	theme	different	695:703	arg1	sugars					730:735	sugars	730:735	sugars	730:735	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	77	theme	different	695:703	arg1	systems					712:718	different frozen systems	695:718	different frozen systems including sugars, starches, proteins, and food	695:765	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	77	theme	different	695:703	arg1	proteins					748:755	proteins	748:755	proteins	748:755	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	77	theme	different	695:703	arg1	food					762:765	food	762:765	food	762:765	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	5	77	theme	different	695:703	arg1	starches					738:745	starches	738:745	starches	738:745	In this article, the data for Tg ', Tm ', and Xs ' of different frozen systems including sugars, starches, proteins, and food are collected and compiled.					
36156387	8	78	theme	frozen	1187:1192	arg1	food					1194:1197	frozen food	1187:1197	frozen food	1187:1197	Both Tg ' and Tm ' values increased with increasing MW of solids in frozen food, reaching an asymptotic value.					
35880492	10	0	theme	foraging	1856:1863	arg1	decision-making					1865:1879	foraging decision-making	1856:1879	foraging decision-making of bumblebees	1856:1893	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	2	1	theme	conservation	391:402	arg1	strategy					404:411	a conservation strategy	389:411	a conservation strategy	389:411	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	2	from	Clarification	222:234	arg1	pollen					332:337	pollen	332:337	pollen	332:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	9	3	theme	phenylpropanoid	1611:1625	arg1	biosynthesis					1627:1638	'phenylpropanoid biosynthesis'	1610:1639	'phenylpropanoid biosynthesis'	1610:1639	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	9	3	theme	phenylpropanoid	1611:1625	arg1	DEPs					1560:1563	DEPs	1560:1563	DEPs involved in 'starch and sucrose metabolism'	1560:1607	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	3	4	theme	research	584:591	arg1	model					593:597	an ideal research model	575:597	an ideal research model for identification of potential substances of bee foraging preference	575:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	5	contain	possesses	462:470	arg1	bicapsularis					420:431	Senna bicapsularis	414:431	Senna bicapsularis	414:431	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	5	contain	possesses	462:470	arg1	plant					451:455	a heterantherous plant	434:455	a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively	434:555	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	5	contain	possesses	462:470	arg2	types					495:499	three different stamen types	472:499	three different stamen types	472:499	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	4	6	theme	pollen	708:713	arg1	compositions					692:703	The lipid and protein compositions	670:703	compositions	692:703	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	2	7	theme	foraging	309:316	arg1	preference					318:327	bee foraging preference	305:327	bee foraging preference	305:327	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	1	8	theme	bees	216:219	arg1	decision-making					197:211	the foraging decision-making	184:211	the foraging decision-making of bees	184:219	Numerous compounds in pollen can affect the foraging decision-making of bees.					
35880492	9	9	theme	acid	1657:1660	arg1	metabolism					1662:1671	'cyanoamino acid metabolism'	1645:1672	'cyanoamino acid metabolism'	1645:1672	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	9	9	theme	acid	1657:1660	arg1	DEPs					1560:1563	DEPs	1560:1563	DEPs involved in 'starch and sucrose metabolism'	1560:1607	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	2	10	theme	components	253:262	arg1	identification					268:281	identification	268:281	identification of key substances for bee foraging preference in pollen	268:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	10	theme	components	253:262	arg1	Clarification					222:234	Clarification	222:234	Clarification of phytochemical components	222:262	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	10	theme	components	253:262	arg1	steps					353:357	essential steps	343:357	essential steps for apiculture	343:372	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	6	11	theme	α-linolenic	1111:1121	arg1	acid					1123:1126	α-linolenic acid	1111:1126	α-linolenic acid	1111:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	6	11	theme	α-linolenic	1111:1121	arg1	pollen					1092:1097	S pollen	1090:1097	S pollen	1090:1097	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	6	12	theme	FAs	1066:1068	arg1	content					1079:1085	the highest FAs and UFAs content	1054:1085	the highest FAs and UFAs content in S pollen, especially α-linolenic acid	1054:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	3	13	theme	bee	645:647	arg1	preference					658:667	bee foraging preference	645:667	bee foraging preference	645:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	8	14	theme	3-oxoacyl-ACP	1414:1426	arg1	protein					1442:1448	3-oxoacyl-ACP synthase-like protein	1414:1448	3-oxoacyl-ACP synthase-like protein	1414:1448	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	8	15	theme	proteomic	1247:1255	arg1	analysis					1257:1264	proteomic analysis	1247:1264	proteomic analysis	1247:1264	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	3	16	theme	substances	631:640	arg1	identification					603:616	identification	603:616	identification of potential substances of bee foraging preference	603:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	1	17	theme	Numerous	144:151	arg1	compounds					153:161	Numerous compounds	144:161	Numerous compounds in pollen	144:171	Numerous compounds in pollen can affect the foraging decision-making of bees.					
35880492	10	18	theme	lipidomic	1784:1792	arg1	profiling					1794:1802	proteomic and lipidomic profiling	1770:1802	proteomic and lipidomic profiling	1770:1802	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	2	19	from	pollen	332:337	arg1	identification					268:281	identification	268:281	identification of key substances for bee foraging preference in pollen	268:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	19	from	pollen	332:337	arg1	Clarification					222:234	Clarification	222:234	Clarification of phytochemical components	222:262	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	19	from	pollen	332:337	arg1	steps					353:357	essential steps	343:357	essential steps for apiculture	343:372	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	8	20	theme	choline/ethanolamine	1454:1473	arg1	phosphotransferase					1475:1492	choline/ethanolamine phosphotransferase 1	1454:1494	choline/ethanolamine phosphotransferase 1	1454:1494	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	8	21	theme	several	1278:1284	arg1	proteins					1311:1318	several differentially expressed proteins	1278:1318	several differentially expressed proteins involved in lipid biosynthesis	1278:1349	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	7	22	theme	substances	1187:1196	arg1	one					1172:1174	one	1172:1174	one	1172:1174	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	7	22	theme	substances	1187:1196	arg1	substances					1187:1196	the key substances	1179:1196	the key substances	1179:1196	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	3	23	theme	preference	658:667	arg1	substances					631:640	potential substances	621:640	potential substances of bee foraging preference	621:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	5	24	theme	short	926:930	arg1	stamens					936:942	short (S) stamens	926:942	short (S) stamens	926:942	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	0	25	from	differentiation	21:35	arg1	stamens					98:104	different intrafloral stamens	76:104	different intrafloral stamens in heterantherous Senna bicapsularis	76:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	4	26	theme	stamens	745:751	arg1	anthers					724:730	the anthers	720:730	the anthers of different stamens of S. bicapsularis	720:770	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	0	27	theme	intrafloral	86:96	arg1	stamens					98:104	different intrafloral stamens	76:104	different intrafloral stamens in heterantherous Senna bicapsularis	76:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	28	from	Characterization	0:15	arg1	stamens					98:104	different intrafloral stamens	76:104	different intrafloral stamens in heterantherous Senna bicapsularis	76:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	8	29	theme	lipid	1332:1336	arg1	biosynthesis					1338:1349	lipid biosynthesis	1332:1349	lipid biosynthesis	1332:1349	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	8	30	with	line	1500:1503	arg1	content					1525:1531	the highest FA content	1510:1531	the highest FA content of S pollen	1510:1543	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	0	31	theme	Senna	124:128	arg1	bicapsularis					130:141	heterantherous Senna bicapsularis	109:141	heterantherous Senna bicapsularis	109:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	1	32	from	compounds	153:161	arg1	pollen					166:171	pollen	166:171	pollen	166:171	Numerous compounds in pollen can affect the foraging decision-making of bees.					
35880492	10	33	from	differences	1755:1765	arg1	profiling					1794:1802	proteomic and lipidomic profiling	1770:1802	proteomic and lipidomic profiling	1770:1802	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	8	34	theme	highest	1514:1520	arg1	content					1525:1531	the highest FA content	1510:1531	the highest FA content of S pollen	1510:1543	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	0	35	theme	different	76:84	arg1	stamens					98:104	different intrafloral stamens	76:104	different intrafloral stamens in heterantherous Senna bicapsularis	76:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	3	36	theme	different	478:486	arg1	types					495:499	three different stamen types	472:499	three different stamen types	472:499	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	7	37	theme	α-linolenic	1146:1156	arg1	acid					1158:1161	α-linolenic acid	1146:1161	α-linolenic acid	1146:1161	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	2	38	from	substances	290:299	arg1	pollen					332:337	pollen	332:337	pollen	332:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	39	theme	substances	290:299	arg1	identification					268:281	identification	268:281	identification of key substances for bee foraging preference in pollen	268:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	39	theme	substances	290:299	arg1	Clarification					222:234	Clarification	222:234	Clarification of phytochemical components	222:262	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	39	theme	substances	290:299	arg1	steps					353:357	essential steps	343:357	essential steps for apiculture	343:372	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	6	40	theme	content	1025:1031	arg1	measurement					1033:1043	the FA content measurement	1018:1043	the FA content measurement	1018:1043	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	8	41	theme	S	1536:1536	arg1	pollen					1538:1543	S pollen	1536:1543	S pollen	1536:1543	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	8	42	theme	S	1378:1378	arg1	pollen					1380:1385	S pollen	1378:1385	S pollen	1378:1385	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	1	43	theme	foraging	188:195	arg1	decision-making					197:211	the foraging decision-making	184:211	the foraging decision-making of bees	184:219	Numerous compounds in pollen can affect the foraging decision-making of bees.					
35880492	0	44	theme	pollen	40:45	arg1	lipidomes					47:55	pollen lipidomes	40:55	pollen lipidomes	40:55	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	5	45	theme	polyunsaturated	808:822	arg1	highest					881:887	highest	881:887	highest	881:887	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	5	45	theme	polyunsaturated	808:822	arg1	PUFAs					837:841	PUFAs	837:841	PUFAs	837:841	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	5	45	theme	polyunsaturated	808:822	arg1	acids					830:834	The polyunsaturated fatty acids	804:834	The polyunsaturated fatty acids (PUFAs)	804:842	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	2	46	theme	key	286:288	arg1	substances					290:299	key substances	286:299	key substances for bee foraging preference in pollen	286:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	9	47	theme	sucrose	1589:1595	arg1	metabolism					1597:1606	sucrose metabolism	1589:1606	sucrose metabolism	1589:1606	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	10	48	theme	different	1820:1828	arg1	types					1837:1841	the three different stamen types	1810:1841	the three different stamen types	1810:1841	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	6	49	theme	UFAs	1074:1077	arg1	content					1079:1085	the highest FAs and UFAs content	1054:1085	the highest FAs and UFAs content in S pollen, especially α-linolenic acid	1054:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	7	50	theme	bee	1202:1204	arg1	preference					1215:1224	bee foraging preference	1202:1224	bee foraging preference	1202:1224	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	3	51	theme	ideal	578:582	arg1	model					593:597	an ideal research model	575:597	an ideal research model for identification of potential substances of bee foraging preference	575:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	4	52	from	anthers	724:730	arg1	compositions					692:703	The lipid and protein compositions	670:703	compositions	692:703	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	8	53	theme	expressed	1301:1309	arg1	proteins					1311:1318	several differentially expressed proteins	1278:1318	several differentially expressed proteins involved in lipid biosynthesis	1278:1349	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	5	54	theme	lipid	895:899	arg1	molecules					901:909	lipid molecules	895:909	lipid molecules	895:909	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	10	55	theme	bumblebees	1884:1893	arg1	decision-making					1865:1879	foraging decision-making	1856:1879	foraging decision-making of bumblebees	1856:1893	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	9	56	theme	cyanoamino	1646:1655	arg1	metabolism					1662:1671	'cyanoamino acid metabolism'	1645:1672	'cyanoamino acid metabolism'	1645:1672	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	9	56	theme	cyanoamino	1646:1655	arg1	DEPs					1560:1563	DEPs	1560:1563	DEPs involved in 'starch and sucrose metabolism'	1560:1607	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	9	57	dep	L	1715:1715	arg1	pollen					1723:1728	pollen	1723:1728	pollen	1723:1728	Additionally, DEPs involved in 'starch and sucrose metabolism', 'phenylpropanoid biosynthesis' and 'cyanoamino acid metabolism' were more represented in S compared with L and M pollen.					
35880492	2	58	theme	essential	343:351	arg1	identification					268:281	identification	268:281	identification of key substances for bee foraging preference in pollen	268:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	58	theme	essential	343:351	arg1	Clarification					222:234	Clarification	222:234	Clarification of phytochemical components	222:262	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	2	58	theme	essential	343:351	arg1	steps					353:357	essential steps	343:357	essential steps for apiculture	343:372	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	0	59	from	stamens	98:104	arg1	differentiation					21:35	differentiation	21:35	differentiation	21:35	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	59	from	stamens	98:104	arg1	lipidomes					47:55	pollen lipidomes	40:55	pollen lipidomes	40:55	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	59	from	stamens	98:104	arg1	Characterization					0:15	Characterization	0:15	Characterization	0:15	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	59	from	stamens	98:104	arg1	bicapsularis					130:141	heterantherous Senna bicapsularis	109:141	heterantherous Senna bicapsularis	109:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	59	from	stamens	98:104	arg1	proteomes					61:69	proteomes	61:69	proteomes	61:69	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	4	60	theme	lipid	674:678	arg1	compositions					692:703	The lipid and protein compositions	670:703	compositions	692:703	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	7	61	from	one	1172:1174	arg1	pollen					1229:1234	pollen	1229:1234	pollen	1229:1234	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	8	62	theme	synthase-like	1428:1440	arg1	protein					1442:1448	3-oxoacyl-ACP synthase-like protein	1414:1448	3-oxoacyl-ACP synthase-like protein	1414:1448	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	4	63	theme	protein	684:690	arg1	compositions					692:703	The lipid and protein compositions	670:703	compositions	692:703	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	3	64	theme	potential	621:629	arg1	substances					631:640	potential substances	621:640	potential substances of bee foraging preference	621:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	6	65	with	consistent	1002:1011	arg1	measurement					1033:1043	the FA content measurement	1018:1043	the FA content measurement	1018:1043	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	2	66	theme	bee	305:307	arg1	preference					318:327	bee foraging preference	305:327	bee foraging preference	305:327	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	4	67	theme	bicapsularis	759:770	arg1	stamens					745:751	different stamens	735:751	different stamens of S. bicapsularis	735:770	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	7	68	theme	key	1183:1185	arg1	substances					1187:1196	the key substances	1179:1196	the key substances	1179:1196	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	3	69	theme	foraging	649:656	arg1	preference					658:667	bee foraging preference	645:667	bee foraging preference	645:667	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	5	70	theme	fatty	824:828	arg1	highest					881:887	highest	881:887	highest	881:887	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	5	70	theme	fatty	824:828	arg1	PUFAs					837:841	PUFAs	837:841	PUFAs	837:841	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	5	70	theme	fatty	824:828	arg1	acids					830:834	The polyunsaturated fatty acids	804:834	The polyunsaturated fatty acids (PUFAs)	804:842	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	4	71	theme	different	735:743	arg1	stamens					745:751	different stamens	735:751	different stamens of S. bicapsularis	735:770	The lipid and protein compositions of pollen from the anthers of different stamens of S. bicapsularis were investigated and compared.					
35880492	0	72	theme	heterantherous	109:122	arg1	bicapsularis					130:141	heterantherous Senna bicapsularis	109:141	heterantherous Senna bicapsularis	109:141	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	3	73	theme	Senna	414:418	arg1	bicapsularis					420:431	Senna bicapsularis	414:431	Senna bicapsularis	414:431	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	73	theme	Senna	414:418	arg1	plant					451:455	a heterantherous plant	434:455	a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively	434:555	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	10	74	theme	proteomic	1770:1778	arg1	profiling					1794:1802	proteomic and lipidomic profiling	1770:1802	proteomic and lipidomic profiling	1770:1802	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	5	75	dep	long	954:957	arg1	stamens					978:984	stamens	978:984	stamens	978:984	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	6	76	theme	highest	1058:1064	arg1	content					1079:1085	the highest FAs and UFAs content	1054:1085	the highest FAs and UFAs content in S pollen, especially α-linolenic acid	1054:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	8	77	theme	FA	1522:1523	arg1	content					1525:1531	the highest FA content	1510:1531	the highest FA content of S pollen	1510:1543	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	5	78	theme	monounsaturated	848:862	arg1	FAs					864:866	monounsaturated FAs	848:866	monounsaturated FAs (MUFAs)	848:874	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	5	78	theme	monounsaturated	848:862	arg1	MUFAs					869:873	MUFAs	869:873	MUFAs	869:873	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	2	79	from	identification	268:281	arg1	pollen					332:337	pollen	332:337	pollen	332:337	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	3	80	theme	heterantherous	436:449	arg1	bicapsularis					420:431	Senna bicapsularis	414:431	Senna bicapsularis	414:431	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	80	theme	heterantherous	436:449	arg1	plant					451:455	a heterantherous plant	434:455	a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively	434:555	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	3	81	theme	stamen	488:493	arg1	types					495:499	three different stamen types	472:499	three different stamen types	472:499	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	5	82	from	stamens	936:942	arg1	pollen					914:919	pollen	914:919	pollen from short (S) stamens	914:942	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	8	83	theme	pollen	1538:1543	arg1	content					1525:1531	the highest FA content	1510:1531	the highest FA content of S pollen	1510:1543	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	5	84	dep	short	926:930	arg1	S					933:933	S	933:933	S	933:933	The polyunsaturated fatty acids (PUFAs) and monounsaturated FAs (MUFAs) were highest among lipid molecules in pollen from short (S) stamens than from long (L) and medium (M) stamens.					
35880492	0	85	theme	lipidomes	47:55	arg1	differentiation					21:35	differentiation	21:35	differentiation	21:35	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	85	theme	lipidomes	47:55	arg1	Characterization					0:15	Characterization	0:15	Characterization	0:15	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	6	86	theme	FA	1022:1023	arg1	content					1025:1031	the FA content	1018:1031	the FA content measurement	1018:1043	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	3	87	theme	same	508:511	arg1	flower					513:518	the same flower	504:518	the same flower	504:518	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	0	88	theme	proteomes	61:69	arg1	differentiation					21:35	differentiation	21:35	differentiation	21:35	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	0	88	theme	proteomes	61:69	arg1	Characterization					0:15	Characterization	0:15	Characterization	0:15	Characterization and differentiation of pollen lipidomes and proteomes from different intrafloral stamens in heterantherous Senna bicapsularis.					
35880492	2	89	theme	phytochemical	239:251	arg1	components					253:262	phytochemical components	239:262	phytochemical components	239:262	Clarification of phytochemical components and identification of key substances for bee foraging preference in pollen are essential steps for apiculture and developing a conservation strategy.					
35880492	6	90	theme	S	1090:1090	arg1	acid					1123:1126	α-linolenic acid	1111:1126	α-linolenic acid	1111:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	6	90	theme	S	1090:1090	arg1	pollen					1092:1097	S pollen	1090:1097	S pollen	1090:1097	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	3	91	from	types	495:499	arg1	flower					513:518	the same flower	504:518	the same flower	504:518	Senna bicapsularis, a heterantherous plant that possesses three different stamen types in the same flower, among which bees forage selectively, provides us with an ideal research model for identification of potential substances of bee foraging preference.					
35880492	10	92	theme	stamen	1830:1835	arg1	types					1837:1841	the three different stamen types	1810:1841	the three different stamen types	1810:1841	The study suggests that differences in proteomic and lipidomic profiling among the three different stamen types might affect foraging decision-making of bumblebees.					
35880492	7	93	theme	foraging	1206:1213	arg1	preference					1215:1224	bee foraging preference	1202:1224	bee foraging preference	1202:1224	We inferred that α-linolenic acid might be one of the key substances for bee foraging preference in pollen.					
35880492	8	94	theme	choline	1396:1402	arg1	kinase					1404:1409	choline kinase 2	1396:1411	choline kinase 2	1396:1411	Moreover, proteomic analysis showed that several differentially expressed proteins involved in lipid biosynthesis were highly accumulated in S pollen, such as choline kinase 2, 3-oxoacyl-ACP synthase-like protein and choline/ethanolamine phosphotransferase 1, in line with the highest FA content of S pollen.					
35880492	6	95	from	content	1079:1085	arg1	acid					1123:1126	α-linolenic acid	1111:1126	α-linolenic acid	1111:1126	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
35880492	6	95	from	content	1079:1085	arg1	pollen					1092:1097	S pollen	1090:1097	S pollen	1090:1097	This result is consistent with the FA content measurement, showing the highest FAs and UFAs content in S pollen, especially α-linolenic acid.					
36397183	3	0	dep	did	689:691	arg1	as					686:687	as	686:687	as	686:687	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	8	1	theme	wheat-based	1784:1794	arg1	products					1801:1808	wheat-based food products	1784:1808	wheat-based food products	1784:1808	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	3	2	dep	destruction	697:707	arg1	the					693:695	the	693:695	the	693:695	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	3	3	theme	gluten	734:739	arg1	network					741:747	the gluten network	730:747	the gluten network	730:747	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	8	4	theme	products	1801:1808	arg1	texture					1755:1761	texture	1755:1761	texture	1755:1761	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	8	4	theme	products	1801:1808	arg1	digestibility					1767:1779	digestibility	1767:1779	digestibility	1767:1779	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	7	5	theme	extensive	1488:1496	arg1	interactions					1527:1538	The more extensive and intensive protein-starch interactions	1479:1538	The more extensive and intensive protein-starch interactions in the 7 + 9 dough	1479:1557	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	2	6	theme	glutenin	350:357	arg1	subunits					359:366	high molecular weight glutenin subunits	328:366	high molecular weight glutenin subunits at the Glu-B1 locus	328:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	1	7	theme	protein-starch	210:223	arg1	interactions					225:236	protein-starch interactions	210:236	protein-starch interactions	210:236	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	0	8	theme	wheat	128:132	arg1	dough					134:138	wheat dough	128:138	wheat dough	128:138	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	2	9	theme	molecular	333:341	arg1	weight					343:348	high molecular weight	328:348	high molecular weight glutenin subunits at the Glu-B1 locus	328:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	5	10	theme	monomeric	1213:1221	arg1	proteins					1223:1230	monomeric proteins	1213:1230	monomeric proteins	1213:1230	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	1	11	theme	digestion	249:257	arg1	characteristics					259:273	starch digestion characteristics	242:273	starch digestion characteristics	242:273	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	1	12	from	interactions	225:236	arg1	matrices					290:297	wheat dough matrices	278:297	wheat dough matrices	278:297	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	2	13	from	effects	317:323	arg1	locus					382:386	the Glu-B1 locus	371:386	the Glu-B1 locus	371:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	13	from	effects	317:323	arg1	quality					408:414	dough processing quality	391:414	dough processing quality	391:414	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	4	14	theme	isomeric	932:939	arg1	bonds					952:956	isomeric glycosidic bonds	932:956	isomeric glycosidic bonds	932:956	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	6	15	theme	protein-starch	1325:1338	arg1	interactions					1340:1351	All protein-starch interactions	1321:1351	All protein-starch interactions in the 7 + 9 dough	1321:1370	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	8	16	theme	starch	1870:1875	arg1	interactions					1841:1852	interactions	1841:1852	interactions	1841:1852	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	8	16	theme	starch	1870:1875	arg1	behavior					1828:1835	behavior	1828:1835	behavior	1828:1835	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	7	17	theme	digestible	1654:1663	arg1	starch					1665:1670	starch	1665:1670	starch	1665:1670	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	3	18	theme	aggregation	626:636	arg1	degree					608:613	the degree	604:613	the degree of protein aggregation	604:636	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	8	19	theme	dough	1884:1888	arg1	processing					1890:1899	dough processing	1884:1899	dough processing	1884:1899	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	2	20	theme	dough	514:518	arg1	samples					520:526	Mixolab dough samples	506:526	Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9	506:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	0	21	theme	starch	69:74	arg1	digestibility					76:88	starch digestibility	69:88	starch digestibility	69:88	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	1	22	theme	glutenin	171:178	arg1	protein					180:186	glutenin protein	171:186	glutenin protein	171:186	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	2	23	theme	lines	549:553	arg1	samples					520:526	Mixolab dough samples	506:526	Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9	506:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	5	24	theme	[from	1134:1138	arg1	82.8 °C					1144:1150	82.8 °C	1144:1150	82.8 °C	1144:1150	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	5	24	theme	[from	1134:1138	arg1	C4					1140:1141	stage [from C4	1128:1141	stage [from C4 (82.8 °C)	1128:1151	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	5	25	theme	compact	984:990	arg1	network					1021:1027	the more compact and extensive protein-starch network	975:1027	the more compact and extensive protein-starch network	975:1027	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	7	26	theme	starch	1616:1621	arg1	hydrolysis					1602:1611	the gelatinization and enzymatic hydrolysis	1569:1611	the gelatinization and enzymatic hydrolysis of starch	1569:1621	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	2	27	theme	near	535:538	arg1	lines					549:553	two near isogenic lines	531:553	two near isogenic lines 7 + 8 and 7 + 9	531:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	4	28	theme	stable	791:796	arg1	network					806:812	the stronger and more stable protein network	769:812	the stronger and more stable protein network formed in 7 + 9 dough	769:834	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	2	29	theme	structural	430:439	arg1	changes					441:447	the detailed structural changes	417:447	the detailed structural changes of protein, starch, and their complexes	417:487	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	6	30	theme	starch	1385:1390	arg1	resistance					1402:1411	the starch digestion resistance	1381:1411	the starch digestion resistance	1381:1411	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	5	31	theme	extensive	996:1004	arg1	network					1021:1027	the more compact and extensive protein-starch network	975:1027	the more compact and extensive protein-starch network	975:1027	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	0	32	theme	HMW-GSs	11:17	arg1	Effects					0:6	Effects	0:6	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.	0:139	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	7	33	theme	enzymatic	1592:1600	arg1	hydrolysis					1602:1611	the gelatinization and enzymatic hydrolysis	1569:1611	the gelatinization and enzymatic hydrolysis of starch	1569:1621	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	0	34	theme	Glu-B1	22:27	arg1	locus					29:33	Glu-B1 locus	22:33	Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough	22:138	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	6	35	from	interactions	1340:1351	arg1	dough					1366:1370	the 7 + 9 dough	1356:1370	the 7 + 9 dough	1356:1370	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	7	36	theme	gelatinization	1573:1586	arg1	hydrolysis					1602:1611	the gelatinization and enzymatic hydrolysis	1569:1611	the gelatinization and enzymatic hydrolysis of starch	1569:1621	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	9	37	theme	Chemical	1920:1927	arg1	Industry					1929:1936	Chemical Industry	1920:1936	Chemical Industry	1920:1936	© 2022 Society of Chemical Industry.					
36397183	3	38	theme	dough	668:672	arg1	processing					674:683	dough processing	668:683	dough processing	668:683	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	4	39	theme	intensive	844:852	arg1	interactions					854:865	intensive interactions	844:865	intensive interactions between protein and starch	844:892	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	6	40	theme	high	1434:1437	arg1	content					1439:1445	the high content	1430:1445	the high content of resistant starch	1430:1465	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	5	41	theme	dough	1082:1086	arg1	pasting					1088:1094	dough pasting	1082:1094	dough pasting	1082:1094	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	5	42	theme	short-chain	1236:1246	arg1	starch					1248:1253	short-chain starch	1236:1253	short-chain starch	1236:1253	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	7	43	theme	7 + 9	1547:1551	arg1	dough					1553:1557	the 7 + 9 dough	1543:1557	the 7 + 9 dough	1543:1557	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	1	44	theme	wheat	278:282	arg1	dough					284:288	wheat dough	278:288	wheat dough matrices	278:297	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	2	45	theme	dough	391:395	arg1	quality					408:414	dough processing quality	391:414	dough processing quality	391:414	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	7	46	theme	protein-starch	1512:1525	arg1	interactions					1527:1538	The more extensive and intensive protein-starch interactions	1479:1538	The more extensive and intensive protein-starch interactions in the 7 + 9 dough	1479:1557	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	2	47	theme	high	328:331	arg1	weight					343:348	high molecular weight	328:348	high molecular weight glutenin subunits at the Glu-B1 locus	328:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	48	from	locus	382:386	arg1	effects					317:323	the effects	313:323	the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality	313:414	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	48	from	locus	382:386	arg1	subunits					359:366	high molecular weight glutenin subunits	328:366	high molecular weight glutenin subunits at the Glu-B1 locus	328:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	8	49	theme	proteins	1857:1864	arg1	interactions					1841:1852	interactions	1841:1852	interactions	1841:1852	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	8	49	theme	proteins	1857:1864	arg1	behavior					1828:1835	behavior	1828:1835	behavior	1828:1835	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	1	50	theme	protein	180:186	arg1	composition					156:166	The composition	152:166	The composition of glutenin protein	152:186	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	3	51	theme	network	741:747	arg1	rearrangement					713:725	rearrangement	713:725	rearrangement	713:725	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	3	51	theme	network	741:747	arg1	destruction					697:707	destruction	697:707	destruction	697:707	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	2	52	theme	subunits	359:366	arg1	effects					317:323	the effects	313:323	the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality	313:414	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	8	53	theme	food	1796:1799	arg1	products					1801:1808	wheat-based food products	1784:1808	wheat-based food products	1784:1808	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	0	54	theme	dough	134:138	arg1	processing					114:123	thermomechanical processing	97:123	thermomechanical processing of wheat dough	97:138	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	2	55	theme	weight	343:348	arg1	subunits					359:366	high molecular weight glutenin subunits	328:366	high molecular weight glutenin subunits at the Glu-B1 locus	328:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	4	56	theme	glycosidic	941:950	arg1	bonds					952:956	isomeric glycosidic bonds	932:956	isomeric glycosidic bonds	932:956	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	1	57	theme	starch	242:247	arg1	characteristics					259:273	starch digestion characteristics	242:273	starch digestion characteristics	242:273	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	7	58	from	interactions	1527:1538	arg1	dough					1553:1557	the 7 + 9 dough	1543:1557	the 7 + 9 dough	1543:1557	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	7	59	theme	resistant	1676:1684	arg1	starch					1686:1691	resistant starch	1676:1691	resistant starch	1676:1691	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	5	60	theme	stage	1128:1132	arg1	82.8 °C					1144:1150	82.8 °C	1144:1150	82.8 °C	1144:1150	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	5	60	theme	stage	1128:1132	arg1	C4					1140:1141	stage [from C4	1128:1141	stage [from C4 (82.8 °C)	1128:1151	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	4	61	theme	hydrogen	913:920	arg1	bonds					922:926	hydrogen bonds	913:926	hydrogen bonds	913:926	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	8	62	dep	texture	1755:1761	arg1	the					1751:1753	the	1751:1753	the	1751:1753	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	5	63	theme	starch	1298:1303	arg1	retrogradation					1305:1318	starch retrogradation	1298:1318	starch retrogradation	1298:1318	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	1	64	from	characteristics	259:273	arg1	matrices					290:297	wheat dough matrices	278:297	wheat dough matrices	278:297	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	7	65	dep	CONCLUSION	1468:1477	arg1	inhibited					1559:1567	inhibited	1559:1567	inhibited	1559:1567	CONCLUSION The more extensive and intensive protein-starch interactions in the 7 + 9 dough inhibited the gelatinization and enzymatic hydrolysis of starch, thereby producing more slowly digestible starch and resistant starch.					
36397183	3	66	theme	protein	618:624	arg1	aggregation					626:636	protein aggregation	618:636	protein aggregation	618:636	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	3	67	dep	RESULTS	572:578	arg1	showed					592:597	showed	592:597	showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network	592:747	RESULTS The results showed that the degree of protein aggregation increased continuously during dough processing, as did the destruction and rearrangement of the gluten network.					
36397183	2	68	theme	Mixolab	506:512	arg1	samples					520:526	Mixolab dough samples	506:526	Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9	506:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	8	69	dep	behavior	1828:1835	arg1	the					1824:1826	the	1824:1826	the	1824:1826	These findings demonstrate the feasibility of optimizing the texture and digestibility of wheat-based food products by regulating the behavior and interactions of proteins and starch during dough processing.					
36397183	6	70	theme	starch	1460:1465	arg1	content					1439:1445	the high content	1430:1445	the high content of resistant starch	1430:1465	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	0	71	theme	thermomechanical	97:112	arg1	processing					114:123	thermomechanical processing	97:123	thermomechanical processing of wheat dough	97:138	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	2	72	theme	isogenic	540:547	arg1	lines					549:553	two near isogenic lines	531:553	two near isogenic lines 7 + 8 and 7 + 9	531:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	1	73	dep	BACKGROUND	141:150	arg1	affects					202:208	affects	202:208	affects protein-starch interactions and starch digestion characteristics in wheat dough matrices	202:297	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36397183	4	74	theme	stronger	773:780	arg1	network					806:812	the stronger and more stable protein network	769:812	the stronger and more stable protein network formed in 7 + 9 dough	769:834	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	6	75	theme	digestion	1392:1400	arg1	resistance					1402:1411	the starch digestion resistance	1381:1411	the starch digestion resistance	1381:1411	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	0	76	from	locus	29:33	arg1	Effects					0:6	Effects	0:6	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.	0:139	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	0	76	from	locus	29:33	arg1	digestibility					76:88	starch digestibility	69:88	starch digestibility	69:88	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	0	76	from	locus	29:33	arg1	interaction					53:63	starch-protein interaction	38:63	starch-protein interaction	38:63	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	2	77	theme	detailed	421:428	arg1	changes					441:447	the detailed structural changes	417:447	the detailed structural changes of protein, starch, and their complexes	417:487	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	5	78	theme	7 + 9	962:966	arg1	dough					968:972	7 + 9 dough	962:972	7 + 9 dough	962:972	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	5	79	theme	protein-starch	1176:1189	arg1	complexes					1191:1199	more protein-starch complexes	1171:1199	more protein-starch complexes composed of monomeric proteins and short-chain starch	1171:1253	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	2	80	theme	starch	461:466	arg1	changes					441:447	the detailed structural changes	417:447	the detailed structural changes of protein, starch, and their complexes	417:487	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	81	theme	protein	452:458	arg1	changes					441:447	the detailed structural changes	417:447	the detailed structural changes of protein, starch, and their complexes	417:487	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	6	82	theme	resistant	1450:1458	arg1	starch					1460:1465	resistant starch	1450:1465	resistant starch	1450:1465	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	2	83	dep	lines	549:553	arg1	7 + 9					565:569	7 + 9	565:569	7 + 9	565:569	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	83	dep	lines	549:553	arg1	7 + 8					555:559	7 + 8	555:559	7 + 8	555:559	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	5	84	theme	starch	1053:1058	arg1	gelatinization					1060:1073	starch gelatinization	1053:1073	starch gelatinization	1053:1073	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	4	85	theme	7 + 9	824:828	arg1	dough					830:834	7 + 9 dough	824:834	7 + 9 dough	824:834	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	0	86	theme	starch-protein	38:51	arg1	interaction					53:63	starch-protein interaction	38:63	starch-protein interaction	38:63	Effects of HMW-GSs at Glu-B1 locus on starch-protein interaction and starch digestibility during thermomechanical processing of wheat dough.					
36397183	2	87	theme	complexes	479:487	arg1	changes					441:447	the detailed structural changes	417:447	the detailed structural changes of protein, starch, and their complexes	417:487	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	2	88	theme	Glu-B1	375:380	arg1	locus					382:386	the Glu-B1 locus	371:386	the Glu-B1 locus	371:386	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	5	89	theme	protein-starch	1006:1019	arg1	network					1021:1027	the more compact and extensive protein-starch network	975:1027	the more compact and extensive protein-starch network	975:1027	In 7 + 9 dough, the more compact and extensive protein-starch network significantly inhibited starch gelatinization during dough pasting, while during the dough cooling stage [from C4 (82.8 °C) to C5 (52.8 °C)], more protein-starch complexes composed of monomeric proteins and short-chain starch were generated, which remarkably inhibited starch retrogradation.					
36397183	6	90	theme	7 + 9	1360:1364	arg1	dough					1366:1370	the 7 + 9 dough	1356:1370	the 7 + 9 dough	1356:1370	All protein-starch interactions in the 7 + 9 dough improved the starch digestion resistance, as reflected by the high content of resistant starch.					
36397183	4	91	theme	protein	798:804	arg1	network					806:812	the stronger and more stable protein network	769:812	the stronger and more stable protein network formed in 7 + 9 dough	769:834	Compared to 7 + 8, the stronger and more stable protein network formed in 7 + 9 dough induced intensive interactions between protein and starch, primarily through hydrogen bonds and isomeric glycosidic bonds.					
36397183	2	92	theme	processing	397:406	arg1	quality					408:414	dough processing quality	391:414	dough processing quality	391:414	To elucidate the effects of high molecular weight glutenin subunits at the Glu-B1 locus on dough processing quality, the detailed structural changes of protein, starch, and their complexes were compared in Mixolab dough samples of two near isogenic lines 7 + 8 and 7 + 9.					
36397183	1	93	theme	dough	284:288	arg1	matrices					290:297	wheat dough matrices	278:297	wheat dough matrices	278:297	BACKGROUND The composition of glutenin protein significantly affects protein-starch interactions and starch digestion characteristics in wheat dough matrices.					
36153160	11	0	theme	samples	1939:1945	arg1	temperature					1924:1934	the glass transition temperature	1903:1934	the glass transition temperature of samples	1903:1945	Breakage accelerated time-dependent crystallization and decreased the crystallization temperature but did not affect the glass transition temperature of samples.					
36153160	4	1	theme	lactose	735:741	arg1	ratios					743:748	different whey protein:lactose ratios	712:748	different whey protein:lactose ratios	712:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	4	2	with	agglomerates	694:705	arg1	ratios					743:748	different whey protein:lactose ratios	712:748	different whey protein:lactose ratios	712:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	3	3	theme	protein-lactose	535:549	arg1	powders					551:557	agglomerated whey protein-lactose powders	517:557	agglomerated whey protein-lactose powders	517:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	2	4	theme	particles	279:287	arg1	factors					367:373	2 main factors	360:373	2 main factors that can be manipulated to reduce breakage	360:416	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	4	theme	particles	279:287	arg1	characteristics					260:274	The characteristics	256:274	The characteristics of particles	256:287	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	4	theme	particles	279:287	arg1	stress					305:310	the applied stress	293:310	the applied stress	293:310	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	1	5	theme	powders	176:182	arg1	breakage					158:165	Particle breakage	149:165	Particle breakage of dairy powders	149:182	Particle breakage of dairy powders occurs easily during many processes, reducing the powder functionality.					
36153160	11	6	theme	crystallization	1856:1870	arg1	temperature					1872:1882	the crystallization temperature	1852:1882	the crystallization temperature	1852:1882	Breakage accelerated time-dependent crystallization and decreased the crystallization temperature but did not affect the glass transition temperature of samples.					
36153160	2	7	theme	processing	317:326	arg1	conditions					328:337	processing conditions	317:337	processing conditions	317:337	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	0	8	theme	protein	119:125	arg1	contents					139:146	protein and lactose contents	119:146	protein and lactose contents	119:146	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	1	9	theme	many	205:208	arg1	processes					210:218	many processes	205:218	many processes	205:218	Particle breakage of dairy powders occurs easily during many processes, reducing the powder functionality.					
36153160	12	10	theme	powders	2003:2009	arg1	composition					1988:1998	composition	1988:1998	composition of powders	1988:2009	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	8	11	theme	lower	1464:1468	arg1	loads					1457:1461	mechanical loads	1446:1461	mechanical loads	1446:1461	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	0	12	theme	lactose	131:137	arg1	contents					139:146	protein and lactose contents	119:146	protein and lactose contents	119:146	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	5	13	theme	physical	846:853	arg1	characteristics					855:869	physical characteristics	846:869	physical characteristics	846:869	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	4	14	theme	different	712:720	arg1	ratios					743:748	different whey protein:lactose ratios	712:748	different whey protein:lactose ratios	712:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	4	15	theme	protein	727:733	arg1	ratios					743:748	different whey protein:lactose ratios	712:748	different whey protein:lactose ratios	712:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	9	16	theme	particle	1607:1614	arg1	size					1616:1619	particle size	1607:1619	particle size	1607:1619	Breakage changed the morphology and surface composition of particles and decreased particle size.					
36153160	3	17	theme	whey	530:533	arg1	powders					551:557	agglomerated whey protein-lactose powders	517:557	agglomerated whey protein-lactose powders	517:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	0	18	from	powders	100:106	arg1	Investigation					0:12	Investigation	0:12	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.	0:147	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	0	19	theme	spray-dried	54:64	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	3	20	theme	particle	602:609	arg1	characteristics					611:625	particle characteristics	602:625	particle characteristics	602:625	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	1	21	theme	Particle	149:156	arg1	breakage					158:165	Particle breakage	149:165	Particle breakage of dairy powders	149:182	Particle breakage of dairy powders occurs easily during many processes, reducing the powder functionality.					
36153160	8	22	theme	multiple	1508:1515	arg1	times					1517:1521	multiple times	1508:1521	multiple times	1508:1521	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	4	23	theme	agglomerates	694:705	arg1	series					678:683	A series	676:683	A series of model agglomerates with different whey protein:lactose ratios	676:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	0	24	theme	whey	79:82	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	12	25	theme	drying	1969:1974	arg1	conditions					1976:1985	the same drying conditions	1960:1985	the same drying conditions	1960:1985	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	5	26	theme	samples	902:908	arg1	composition					872:882	composition	872:882	composition	872:882	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	5	26	theme	samples	902:908	arg1	structure					889:897	structure	889:897	structure	889:897	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	5	26	theme	samples	902:908	arg1	characteristics					855:869	physical characteristics	846:869	physical characteristics	846:869	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	2	27	from	conditions	328:337	arg1	factors					367:373	2 main factors	360:373	2 main factors that can be manipulated to reduce breakage	360:416	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	27	from	conditions	328:337	arg1	characteristics					260:274	The characteristics	256:274	The characteristics of particles	256:287	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	27	from	conditions	328:337	arg1	stress					305:310	the applied stress	293:310	the applied stress	293:310	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	0	28	from	Investigation	0:12	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	8	29	theme	moisture	1368:1375	arg1	content					1377:1383	the moisture content	1364:1383	the moisture content	1364:1383	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	0	30	from	effects	43:49	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	4	31	theme	same	774:777	arg1	conditions					792:801	the same spray-drying conditions	770:801	the same spray-drying conditions	770:801	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	10	32	theme	wetting	1688:1694	arg1	time					1696:1699	the wetting time	1684:1699	the wetting time of wettable samples	1684:1719	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	9	33	theme	particles	1583:1591	arg1	morphology					1545:1554	morphology	1545:1554	morphology	1545:1554	Breakage changed the morphology and surface composition of particles and decreased particle size.					
36153160	9	33	theme	particles	1583:1591	arg1	composition					1568:1578	surface composition	1560:1578	surface composition	1560:1578	Breakage changed the morphology and surface composition of particles and decreased particle size.					
36153160	6	34	theme	particle	1087:1094	arg1	higher					1170:1175	higher	1170:1175	higher	1170:1175	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	6	34	theme	particle	1087:1094	arg1	size					1096:1099	particle size	1087:1099	particle size	1087:1099	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	0	35	theme	agglomerated	66:77	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	9	36	dep	morphology	1545:1554	arg1	the					1541:1543	the	1541:1543	the	1541:1543	Breakage changed the morphology and surface composition of particles and decreased particle size.					
36153160	5	37	theme	different	943:951	arg1	stresses					964:971	different mechanical stresses	943:971	different mechanical stresses	943:971	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	4	38	theme	pilot	814:818	arg1	trial					826:830	a pilot plant trial	812:830	a pilot plant trial	812:830	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	10	39	theme	samples	1713:1719	arg1	time					1696:1699	the wetting time	1684:1699	the wetting time of wettable samples	1684:1719	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	0	40	theme	breakage	17:24	arg1	behavior					26:33	breakage behavior	17:33	breakage behavior	17:33	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	3	41	theme	dairy	653:657	arg1	breakage					666:673	unwanted dairy powder breakage	644:673	unwanted dairy powder breakage	644:673	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	8	42	theme	particle	1415:1422	arg1	breakage					1424:1431	particle breakage	1415:1431	particle breakage	1415:1431	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	10	43	theme	wetting	1739:1745	arg1	time					1747:1750	the wetting time	1735:1750	the wetting time of powders with poor wettability	1735:1783	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	0	44	theme	effects	43:49	arg1	Investigation					0:12	Investigation	0:12	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.	0:147	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	5	45	theme	powders	1048:1054	arg1	rehydration					995:1005	the rehydration and water adsorption properties	991:1037	rehydration	995:1005	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	5	45	theme	powders	1048:1054	arg1	properties					1028:1037	the rehydration and water adsorption properties	991:1037	properties	1028:1037	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	8	46	theme	mechanical	1446:1455	arg1	loads					1457:1461	mechanical loads	1446:1461	mechanical loads	1446:1461	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	3	47	theme	whey	460:463	arg1	protein					465:471	whey protein	460:471	whey protein	460:471	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	3	48	theme	agglomerated	517:528	arg1	powders					551:557	agglomerated whey protein-lactose powders	517:557	agglomerated whey protein-lactose powders	517:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	3	49	theme	dynamic	497:503	arg1	breakage					505:512	dynamic breakage	497:512	dynamic breakage in agglomerated whey protein-lactose powders	497:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	1	50	theme	powder	234:239	arg1	functionality					241:253	the powder functionality	230:253	the powder functionality	230:253	Particle breakage of dairy powders occurs easily during many processes, reducing the powder functionality.					
36153160	10	51	theme	poor	1768:1771	arg1	wettability					1773:1783	poor wettability	1768:1783	poor wettability	1768:1783	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	5	52	theme	adsorption	1017:1026	arg1	properties					1028:1037	the rehydration and water adsorption properties	991:1037	properties	1028:1037	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	2	53	theme	main	362:365	arg1	characteristics					260:274	The characteristics	256:274	The characteristics of particles	256:287	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	53	theme	main	362:365	arg1	factors					367:373	2 main factors	360:373	2 main factors that can be manipulated to reduce breakage	360:416	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	53	theme	main	362:365	arg1	stress					305:310	the applied stress	293:310	the applied stress	293:310	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	12	54	theme	particles	2096:2104	arg1	properties					2076:2085	the physical properties	2063:2085	the physical properties of their particles, which resulted in deteriorated functionality	2063:2150	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	7	55	theme	dynamic	1271:1277	arg1	breakage					1279:1286	dynamic breakage	1271:1286	dynamic breakage for samples with more lactose	1271:1316	This resulted in higher particle breakage during dynamic breakage for samples with more lactose.					
36153160	2	56	theme	applied	297:303	arg1	characteristics					260:274	The characteristics	256:274	The characteristics of particles	256:287	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	56	theme	applied	297:303	arg1	factors					367:373	2 main factors	360:373	2 main factors that can be manipulated to reduce breakage	360:416	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	2	56	theme	applied	297:303	arg1	stress					305:310	the applied stress	293:310	the applied stress	293:310	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	12	57	theme	deteriorated	2125:2136	arg1	functionality					2138:2150	deteriorated functionality	2125:2150	deteriorated functionality	2125:2150	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	11	58	theme	transition	1913:1922	arg1	temperature					1924:1934	the glass transition temperature	1903:1934	the glass transition temperature of samples	1903:1945	Breakage accelerated time-dependent crystallization and decreased the crystallization temperature but did not affect the glass transition temperature of samples.					
36153160	7	59	with	samples	1292:1298	arg1	lactose					1310:1316	more lactose	1305:1316	more lactose	1305:1316	This resulted in higher particle breakage during dynamic breakage for samples with more lactose.					
36153160	3	60	from	breakage	505:512	arg1	powders					551:557	agglomerated whey protein-lactose powders	517:557	agglomerated whey protein-lactose powders	517:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	1	61	theme	dairy	170:174	arg1	powders					176:182	dairy powders	170:182	dairy powders	170:182	Particle breakage of dairy powders occurs easily during many processes, reducing the powder functionality.					
36153160	12	62	theme	physical	2067:2074	arg1	properties					2076:2085	the physical properties	2063:2085	the physical properties of their particles, which resulted in deteriorated functionality	2063:2150	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	6	63	with	agglomerates	1121:1132	arg1	lactose					1144:1150	more lactose	1139:1150	more lactose	1139:1150	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	7	64	theme	higher	1239:1244	arg1	breakage					1255:1262	higher particle breakage	1239:1262	higher particle breakage	1239:1262	This resulted in higher particle breakage during dynamic breakage for samples with more lactose.					
36153160	3	65	theme	useful	570:575	arg1	information					577:587	useful information	570:587	useful information	570:587	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	3	66	theme	contents	485:492	arg1	effect					450:455	the effect	446:455	the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders	446:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	0	67	theme	contents	139:146	arg1	Effect					109:114	Effect	109:114	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.	0:147	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	8	68	theme	particles	1491:1499	arg1	strength					1479:1486	the strength	1475:1486	the strength of particles	1475:1499	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	3	69	theme	characteristics	611:625	arg1	terms					593:597	terms	593:597	terms of particle characteristics	593:625	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	5	70	theme	dynamic	920:926	arg1	breakage					928:935	dynamic breakage	920:935	dynamic breakage	920:935	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	4	71	theme	whey	722:725	arg1	ratios					743:748	different whey protein:lactose ratios	712:748	different whey protein:lactose ratios	712:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	7	72	theme	particle	1246:1253	arg1	breakage					1255:1262	higher particle breakage	1239:1262	higher particle breakage	1239:1262	This resulted in higher particle breakage during dynamic breakage for samples with more lactose.					
36153160	0	73	from	behavior	26:33	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	8	74	theme	agglomerates	1335:1346	arg1	breakage					1323:1330	The breakage	1319:1330	The breakage of agglomerates	1319:1346	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	0	75	theme	protein-lactose	84:98	arg1	powders					100:106	spray-dried agglomerated whey protein-lactose powders	54:106	spray-dried agglomerated whey protein-lactose powders	54:106	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	2	76	from	stress	305:310	arg1	particles					346:354	the particles	342:354	the particles	342:354	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	4	77	theme	model	688:692	arg1	agglomerates					694:705	model agglomerates	688:705	model agglomerates with different whey protein:lactose ratios	688:748	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	9	78	theme	surface	1560:1566	arg1	composition					1568:1578	surface composition	1560:1578	surface composition	1560:1578	Breakage changed the morphology and surface composition of particles and decreased particle size.					
36153160	11	79	theme	glass	1907:1911	arg1	temperature					1924:1934	the glass transition temperature	1903:1934	the glass transition temperature of samples	1903:1945	Breakage accelerated time-dependent crystallization and decreased the crystallization temperature but did not affect the glass transition temperature of samples.					
36153160	11	80	theme	time-dependent	1807:1820	arg1	crystallization					1822:1836	time-dependent crystallization	1807:1836	time-dependent crystallization	1807:1836	Breakage accelerated time-dependent crystallization and decreased the crystallization temperature but did not affect the glass transition temperature of samples.					
36153160	10	81	theme	powders	1662:1668	arg1	dispersibility					1644:1657	the dispersibility	1640:1657	the dispersibility of powders	1640:1668	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	12	82	theme	same	1964:1967	arg1	conditions					1976:1985	the same drying conditions	1960:1985	the same drying conditions	1960:1985	Thus, under the same drying conditions, composition of powders significantly affected breakage, mainly by altering the physical properties of their particles, which resulted in deteriorated functionality.					
36153160	8	83	theme	powders	1388:1394	arg1	content					1377:1383	the moisture content	1364:1383	the moisture content	1364:1383	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	0	84	theme	behavior	26:33	arg1	Investigation					0:12	Investigation	0:12	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.	0:147	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	5	85	theme	mechanical	953:962	arg1	stresses					964:971	different mechanical stresses	943:971	different mechanical stresses	943:971	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	3	86	theme	unwanted	644:651	arg1	breakage					666:673	unwanted dairy powder breakage	644:673	unwanted dairy powder breakage	644:673	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	8	87	theme	fatigue	1400:1406	arg1	content					1377:1383	the moisture content	1364:1383	the moisture content	1364:1383	The breakage of agglomerates was affected by the moisture content of powders and fatigue, where particle breakage happens when mechanical loads, lower than the strength of particles, occur multiple times.					
36153160	10	88	theme	wettable	1704:1711	arg1	samples					1713:1719	wettable samples	1704:1719	wettable samples	1704:1719	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	2	89	from	characteristics	260:274	arg1	particles					346:354	the particles	342:354	the particles	342:354	The characteristics of particles and the applied stress from processing conditions on the particles are 2 main factors that can be manipulated to reduce breakage.					
36153160	5	90	theme	model	1042:1046	arg1	powders					1048:1054	model powders	1042:1054	model powders	1042:1054	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	7	91	theme	more	1305:1308	arg1	lactose					1310:1316	more lactose	1305:1316	more lactose	1305:1316	This resulted in higher particle breakage during dynamic breakage for samples with more lactose.					
36153160	4	92	theme	plant	820:824	arg1	trial					826:830	a pilot plant trial	812:830	a pilot plant trial	812:830	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	3	93	from	effect	450:455	arg1	breakage					505:512	dynamic breakage	497:512	dynamic breakage in agglomerated whey protein-lactose powders	497:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	3	94	theme	lactose	477:483	arg1	contents					485:492	lactose contents	477:492	lactose contents	477:492	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	0	95	dep	Investigation	0:12	arg1	Effect					109:114	Effect	109:114	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.	0:147	Investigation of breakage behavior and its effects on spray-dried agglomerated whey protein-lactose powders: Effect of protein and lactose contents.					
36153160	6	96	theme	more	1139:1142	arg1	lactose					1144:1150	more lactose	1139:1150	more lactose	1139:1150	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	3	97	theme	powder	659:664	arg1	breakage					666:673	unwanted dairy powder breakage	644:673	unwanted dairy powder breakage	644:673	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	4	98	theme	spray-drying	779:790	arg1	conditions					792:801	the same spray-drying conditions	770:801	the same spray-drying conditions	770:801	A series of model agglomerates with different whey protein:lactose ratios were produced under the same spray-drying conditions, through a pilot plant trial.					
36153160	3	99	theme	protein	465:471	arg1	effect					450:455	the effect	446:455	the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders	446:557	In this study, we explored the effect of whey protein and lactose contents on dynamic breakage in agglomerated whey protein-lactose powders to provide useful information, in terms of particle characteristics, for controlling unwanted dairy powder breakage.					
36153160	10	100	with	powders	1755:1761	arg1	wettability					1773:1783	poor wettability	1768:1783	poor wettability	1768:1783	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
36153160	5	101	theme	water	1011:1015	arg1	properties					1028:1037	the rehydration and water adsorption properties	991:1037	properties	1028:1037	We evaluated physical characteristics, composition, and structure of samples; analyzed dynamic breakage under different mechanical stresses; and investigated the rehydration and water adsorption properties of model powders before and after breakage.					
36153160	6	102	theme	agglomerates	1121:1132	arg1	irregularity					1105:1116	irregularity	1105:1116	irregularity	1105:1116	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	6	102	theme	agglomerates	1121:1132	arg1	higher					1170:1175	higher	1170:1175	higher	1170:1175	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	6	102	theme	agglomerates	1121:1132	arg1	size					1096:1099	particle size	1087:1099	particle size	1087:1099	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	6	103	contain	contained	1198:1206	arg2	protein					1213:1219	more protein	1208:1219	more protein	1208:1219	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	6	103	contain	contained	1198:1206	arg1	samples					1185:1191	samples	1185:1191	samples that contained more protein	1185:1219	The particle size and irregularity of agglomerates with more lactose was significantly higher than of samples that contained more protein.					
36153160	10	104	theme	powders	1755:1761	arg1	time					1747:1750	the wetting time	1735:1750	the wetting time of powders with poor wettability	1735:1783	It also decreased the dispersibility of powders and increased the wetting time of wettable samples but decreased the wetting time of powders with poor wettability.					
37014871	4	0	theme	offspring	664:672	arg1	ahead					696:700	the offspring intestinal microbiome ahead	660:700	the offspring intestinal microbiome ahead of asthma model establishment	660:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	2	1	from	inulin	300:305	arg1	abundant					288:295	abundant	288:295	abundant	288:295	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	7	2	theme	asthma	1464:1469	arg1	onset					1455:1459	the onset	1451:1459	the onset of asthma	1451:1469	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	5	3	theme	lung	886:889	arg1	indexes					904:910	lung inflammation indexes	886:910	lung inflammation indexes	886:910	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	7	4	theme	intestinal	1543:1552	arg1	microbiome					1554:1563	offspring's intestinal microbiome	1531:1563	offspring's intestinal microbiome	1531:1563	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	0	5	theme	fatty	114:118	arg1	acids					120:124	short-chain fatty acids	102:124	short-chain fatty acids	102:124	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	4	6	theme	microbiome	763:772	arg1	formations					646:655	the formations	642:655	the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence	642:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	6	theme	microbiome	763:772	arg1	SCFAs					840:844	SCFAs	840:844	SCFAs	840:844	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	6	theme	microbiome	763:772	arg1	acids					833:837	the short-chain fatty acids	811:837	the short-chain fatty acids (SCFAs)	811:845	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	6	7	theme	inflammatory	1261:1272	arg1	response					1274:1281	the asthmatic inflammatory response	1247:1281	the asthmatic inflammatory response in the offspring	1247:1298	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	5	8	theme	acid	976:979	arg1	receptors					981:989	short-chain fatty acid receptors	958:989	short-chain fatty acid receptors (GPR41, GPR43)	958:1004	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	0	9	theme	short-chain	102:112	arg1	acids					120:124	short-chain fatty acids	102:124	short-chain fatty acids	102:124	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	6	10	theme	intestinal	1118:1127	arg1	composition					1140:1150	altered maternal intestinal microbiome composition	1101:1150	altered maternal intestinal microbiome composition	1101:1150	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	4	11	theme	metabolomic	850:860	arg1	analysis					862:869	metabolomic analysis	850:869	metabolomic analysis	850:869	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	6	12	theme	asthmatic	1251:1259	arg1	response					1274:1281	the asthmatic inflammatory response	1247:1281	the asthmatic inflammatory response in the offspring	1247:1298	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	3	13	theme	inulin-included	520:534	arg1	water					545:549	inulin-included drinking water	520:549	inulin-included drinking water	520:549	In this study, rats were given with inulin-included drinking water, whereas in normal group rats were allowed with normal water.					
37014871	6	14	theme	Inulin	1075:1080	arg1	intake					1082:1087	Inulin intake	1075:1087	Inulin intake	1075:1087	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	5	15	theme	qPCR	1063:1066	arg1	assay					1068:1072	qPCR assay	1063:1072	qPCR assay	1063:1072	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	4	16	theme	intestinal	752:761	arg1	microbiome					763:772	the maternal intestinal microbiome	739:772	the maternal intestinal microbiome through high throughput sequence	739:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	7	17	from	impacts	1520:1526	arg1	procession					1575:1584	asthma procession	1568:1584	asthma procession	1568:1584	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	4	18	theme	fatty	827:831	arg1	SCFAs					840:844	SCFAs	840:844	SCFAs	840:844	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	18	theme	fatty	827:831	arg1	acids					833:837	the short-chain fatty acids	811:837	the short-chain fatty acids (SCFAs)	811:845	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	19	theme	maternal	743:750	arg1	microbiome					763:772	the maternal intestinal microbiome	739:772	the maternal intestinal microbiome through high throughput sequence	739:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	7	20	theme	offspring	1405:1413	arg1	microbiome					1387:1396	the intestinal microbiome	1372:1396	the intestinal microbiome of the offspring	1372:1413	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	6	21	theme	microbiome	1129:1138	arg1	composition					1140:1150	altered maternal intestinal microbiome composition	1101:1150	altered maternal intestinal microbiome composition	1101:1150	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	4	22	theme	model	712:716	arg1	establishment					718:730	asthma model establishment	705:730	asthma model establishment	705:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	6	23	from	response	1274:1281	arg1	offspring					1290:1298	the offspring	1286:1298	the offspring	1286:1298	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	4	24	theme	asthma	705:710	arg1	establishment					718:730	asthma model establishment	705:730	asthma model establishment	705:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	2	25	theme	potential	367:375	arg1	value					377:381	a potential value	365:381	a potential value	365:381	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	5	26	theme	receptors	981:989	arg1	expression					944:953	the expression	940:953	the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models	940:1038	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	3	27	theme	drinking	536:543	arg1	water					545:549	inulin-included drinking water	520:549	inulin-included drinking water	520:549	In this study, rats were given with inulin-included drinking water, whereas in normal group rats were allowed with normal water.					
37014871	7	28	theme	intestinal	1376:1385	arg1	microbiome					1387:1396	the intestinal microbiome	1372:1396	the intestinal microbiome of the offspring	1372:1413	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	1	29	theme	maternal	199:206	arg1	diet					219:222	its maternal high-fiber diet	195:222	its maternal high-fiber diet as well as the intestinal microbiome	195:259	Technically, symptom of offspring asthma is also closely reliant on its maternal high-fiber diet as well as the intestinal microbiome.					
37014871	2	30	theme	maternal	423:430	arg1	intake					432:437	the maternal intake	419:437	the maternal intake	419:437	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	5	31	theme	asthma	1026:1031	arg1	models					1033:1038	asthma models	1026:1038	asthma models	1026:1038	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	4	32	theme	establishment	718:730	arg1	ahead					696:700	the offspring intestinal microbiome ahead	660:700	the offspring intestinal microbiome ahead of asthma model establishment	660:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	1	33	theme	high-fiber	208:217	arg1	diet					219:222	its maternal high-fiber diet	195:222	its maternal high-fiber diet as well as the intestinal microbiome	195:259	Technically, symptom of offspring asthma is also closely reliant on its maternal high-fiber diet as well as the intestinal microbiome.					
37014871	4	34	theme	intestinal	674:683	arg1	ahead					696:700	the offspring intestinal microbiome ahead	660:700	the offspring intestinal microbiome ahead of asthma model establishment	660:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	5	35	theme	models	1033:1038	arg1	offspring					1013:1021	the offspring	1009:1021	the offspring of asthma models	1009:1038	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	3	36	theme	group	570:574	arg1	rats					576:579	normal group rats	563:579	normal group rats	563:579	In this study, rats were given with inulin-included drinking water, whereas in normal group rats were allowed with normal water.					
37014871	6	37	theme	significant	1160:1170	arg1	increase					1172:1179	a significant increase	1158:1179	a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium)	1158:1232	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	7	38	theme	microbiome	1387:1396	arg1	composition					1357:1367	the composition	1353:1367	the composition of the intestinal microbiome of the offspring	1353:1413	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	2	39	theme	asthma	396:401	arg1	control					403:409	asthma control	396:409	asthma control	396:409	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	0	40	theme	intestinal	56:65	arg1	composition					78:88	maternal intestinal microbiome composition	47:88	maternal intestinal microbiome composition	47:88	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	6	41	dep	bacteria	1200:1207	arg1	Bifidobacterium					1217:1231	Bifidobacterium	1217:1231	Bifidobacterium	1217:1231	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	4	42	theme	short-chain	815:825	arg1	SCFAs					840:844	SCFAs	840:844	SCFAs	840:844	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	42	theme	short-chain	815:825	arg1	acids					833:837	the short-chain fatty acids	811:837	the short-chain fatty acids (SCFAs)	811:845	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	43	theme	microbiome	685:694	arg1	ahead					696:700	the offspring intestinal microbiome ahead	660:700	the offspring intestinal microbiome ahead of asthma model establishment	660:730	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	0	44	theme	maternal	47:54	arg1	composition					78:88	maternal intestinal microbiome composition	47:88	maternal intestinal microbiome composition	47:88	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	7	45	theme	inulin	1312:1317	arg1	Meanwhile					1301:1309	Meanwhile	1301:1309	Meanwhile	1301:1309	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	7	45	theme	inulin	1312:1317	arg1	intake					1319:1324	inulin intake	1312:1324	inulin intake during pregnancy	1312:1341	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	2	46	with	endowed	352:358	arg1	value					377:381	a potential value	365:381	a potential value	365:381	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	3	47	theme	normal	563:568	arg1	rats					576:579	normal group rats	563:579	normal group rats	563:579	In this study, rats were given with inulin-included drinking water, whereas in normal group rats were allowed with normal water.					
37014871	2	48	theme	dietary	335:341	arg1	fiber					343:347	this naturally soluble dietary fiber	312:347	this naturally soluble dietary fiber	312:347	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	4	49	theme	high	782:785	arg1	sequence					798:805	high throughput sequence	782:805	high throughput sequence	782:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	6	50	theme	SCFAs-producing	1184:1198	arg1	bacteria					1200:1207	SCFAs-producing bacteria	1184:1207	SCFAs-producing bacteria (mainly Bifidobacterium)	1184:1232	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	5	51	theme	fatty	970:974	arg1	receptors					981:989	short-chain fatty acid receptors	958:989	short-chain fatty acid receptors (GPR41, GPR43)	958:1004	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	2	52	theme	soluble	327:333	arg1	fiber					343:347	this naturally soluble dietary fiber	312:347	this naturally soluble dietary fiber	312:347	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	6	53	theme	maternal	1109:1116	arg1	composition					1140:1150	altered maternal intestinal microbiome composition	1101:1150	altered maternal intestinal microbiome composition	1101:1150	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	7	54	theme	asthma	1568:1573	arg1	procession					1575:1584	asthma procession	1568:1584	asthma procession	1568:1584	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	5	55	theme	short-chain	958:968	arg1	receptors					981:989	short-chain fatty acid receptors	958:989	short-chain fatty acid receptors (GPR41, GPR43)	958:1004	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	5	56	theme	inflammation	891:902	arg1	indexes					904:910	lung inflammation indexes	886:910	lung inflammation indexes	886:910	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	3	57	theme	normal	599:604	arg1	water					606:610	normal water	599:610	normal water	599:610	In this study, rats were given with inulin-included drinking water, whereas in normal group rats were allowed with normal water.					
37014871	4	58	theme	ahead	696:700	arg1	formations					646:655	the formations	642:655	the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence	642:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	58	theme	ahead	696:700	arg1	SCFAs					840:844	SCFAs	840:844	SCFAs	840:844	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	4	58	theme	ahead	696:700	arg1	acids					833:837	the short-chain fatty acids	811:837	the short-chain fatty acids (SCFAs)	811:845	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	6	59	dep	Bifidobacterium	1217:1231	arg1	mainly					1210:1215	mainly	1210:1215	mainly	1210:1215	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	5	60	from	expression	944:953	arg1	offspring					1013:1021	the offspring	1009:1021	the offspring of asthma models	1009:1038	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	4	61	theme	throughput	787:796	arg1	sequence					798:805	high throughput sequence	782:805	high throughput sequence	782:805	Afterwards, we analyzed both the formations of the offspring intestinal microbiome ahead of asthma model establishment and of the maternal intestinal microbiome through high throughput sequence and the short-chain fatty acids (SCFAs) by metabolomic analysis.					
37014871	5	62	dep	receptors	981:989	arg1	GPR43					999:1003	GPR43	999:1003	GPR43	999:1003	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	5	62	dep	receptors	981:989	arg1	GPR41					992:996	GPR41	992:996	GPR41	992:996	Subsequently, lung inflammation indexes were detected by Elisa, and the expression of short-chain fatty acid receptors (GPR41, GPR43) in the offspring of asthma models were evaluated through qPCR assay.					
37014871	1	63	theme	offspring	151:159	arg1	asthma					161:166	offspring asthma	151:166	offspring asthma	151:166	Technically, symptom of offspring asthma is also closely reliant on its maternal high-fiber diet as well as the intestinal microbiome.					
37014871	2	64	from	abundant	288:295	arg1	inulin					300:305	inulin	300:305	inulin	300:305	Fruits and vegetables are abundant in inulin, and this naturally soluble dietary fiber is endowed with a potential value on offspring asthma control through the maternal intake, but the mechanism now remains less studied.					
37014871	7	65	theme	microbiome	1554:1563	arg1	impacts					1520:1526	the impacts	1516:1526	the impacts of offspring's intestinal microbiome on asthma procession	1516:1584	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	0	66	theme	microbiome	67:76	arg1	composition					78:88	maternal intestinal microbiome composition	47:88	maternal intestinal microbiome composition	47:88	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	6	67	theme	altered	1101:1107	arg1	composition					1140:1150	altered maternal intestinal microbiome composition	1101:1150	altered maternal intestinal microbiome composition	1101:1150	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	0	68	theme	offspring	18:26	arg1	asthma					28:33	offspring asthma	18:33	offspring asthma	18:33	Inulin alleviates offspring asthma by altering maternal intestinal microbiome composition to increase short-chain fatty acids.					
37014871	7	69	theme	further	1495:1501	arg1	studies					1503:1509	further studies	1495:1509	further studies	1495:1509	Meanwhile, inulin intake during pregnancy modulates the composition of the intestinal microbiome of the offspring, and this alteration appears before the onset of asthma, hence, there should be further studies onto the impacts of offspring's intestinal microbiome on asthma procession.					
37014871	1	70	theme	asthma	161:166	arg1	symptom					140:146	symptom	140:146	symptom of offspring asthma	140:166	Technically, symptom of offspring asthma is also closely reliant on its maternal high-fiber diet as well as the intestinal microbiome.					
37014871	6	71	from	increase	1172:1179	arg1	bacteria					1200:1207	SCFAs-producing bacteria	1184:1207	SCFAs-producing bacteria (mainly Bifidobacterium)	1184:1232	Inulin intake resulted in altered maternal intestinal microbiome composition, with a significant increase in SCFAs-producing bacteria (mainly Bifidobacterium), attenuating the asthmatic inflammatory response in the offspring.					
37014871	1	72	theme	intestinal	239:248	arg1	microbiome					250:259	the intestinal microbiome	235:259	its maternal high-fiber diet as well as the intestinal microbiome	195:259	Technically, symptom of offspring asthma is also closely reliant on its maternal high-fiber diet as well as the intestinal microbiome.					
35651022	2	0	used	used	427:430	arg2	works					421:425	the published works	407:425	the published works	407:425	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	2	0	used	used	427:430	arg2	most					399:402	most	399:402	most	399:402	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	0	1	theme	colon	138:142	arg1	model					112:116	an in vitro model	100:116	an in vitro model of the human distal colon	100:142	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	3	2	theme	seaweed	625:631	arg1	elongata					645:652	a brown whole seaweed Himanthalia elongata	611:652	a brown whole seaweed Himanthalia elongata	611:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	1	3	theme	seaweed	228:234	arg1	carbohydrates					236:248	seaweed carbohydrates	228:248	seaweed carbohydrates	228:248	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	6	4	theme	Bacteoides	1093:1102	arg1	ovatus					1104:1109	the specie Bacteoides ovatus	1082:1109	the specie Bacteoides ovatus	1082:1109	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	3	5	theme	brown	613:617	arg1	elongata					645:652	a brown whole seaweed Himanthalia elongata	611:652	a brown whole seaweed Himanthalia elongata	611:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	11	6	dep	H.	1911:1912	arg1	elongata					1914:1921	H. elongata	1911:1921	H. elongata	1911:1921	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	4	7	theme	entire	764:769	arg1	digestion					788:796	the entire gastrointestinal digestion	760:796	the entire gastrointestinal digestion	760:796	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	1	8	with	studies	254:260	arg1	seaweeds					277:284	the whole seaweeds	267:284	the whole seaweeds	267:284	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	3	9	theme	prebiotic	591:599	arg1	effect					601:606	the potential prebiotic effect	577:606	the potential prebiotic effect of a brown whole seaweed Himanthalia elongata	577:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	10	10	theme	metabolic	1715:1723	arg1	different					1790:1798	different	1790:1798	different	1790:1798	The metabolic pathways associated with bacterial genera were not significantly different between the two tested substrates.					
35651022	10	10	theme	metabolic	1715:1723	arg1	pathways					1725:1732	The metabolic pathways	1711:1732	The metabolic pathways associated with bacterial genera	1711:1765	The metabolic pathways associated with bacterial genera were not significantly different between the two tested substrates.					
35651022	11	11	theme	Food	2064:2067	arg1	Chemistry					2069:2077	Food Chemistry	2064:2077	Food Chemistry	2064:2077	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	11	12	theme	research	2010:2017	arg1	opportunities					1993:2005	new opportunities	1989:2005	new opportunities of research and application	1989:2033	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	11	13	theme	H.	1911:1912	arg1	character					1898:1906	the prebiotic character	1884:1906	the prebiotic character of H. elongata	1884:1921	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	11	14	theme	Chemistry	2069:2077	arg1	area					2042:2045	the area	2038:2045	the area of Nutrition and Food Chemistry	2038:2077	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	3	15	theme	elongata	645:652	arg1	effect					601:606	the potential prebiotic effect	577:606	the potential prebiotic effect of a brown whole seaweed Himanthalia elongata	577:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	8	16	theme	significative	1350:1362	arg1	differences					1364:1374	no significative differences	1347:1374	no significative differences in Bifidobacterium population	1347:1404	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	6	17	theme	Parabacteroides	1150:1164	arg1	genus					1166:1170	the Parabacteroides genus	1146:1170	the Parabacteroides genus	1146:1170	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	10	18	theme	bacterial	1750:1758	arg1	genera					1760:1765	bacterial genera	1750:1765	bacterial genera	1750:1765	The metabolic pathways associated with bacterial genera were not significantly different between the two tested substrates.					
35651022	9	19	theme	acid	1656:1659	arg1	production					1661:1670	total acid production	1650:1670	total acid production	1650:1670	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	3	20	theme	human	515:519	arg1	colon					528:532	the human distal colon	511:532	the human distal colon	511:532	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	11	21	theme	application	2023:2033	arg1	opportunities					1993:2005	new opportunities	1989:2005	new opportunities of research and application	1989:2033	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	9	22	theme	acid	1519:1522	arg1	production					1524:1533	the short-fatty acid production	1503:1533	the short-fatty acid production	1503:1533	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	6	23	theme	identified	1224:1233	arg1	specie					1235:1240	the most abundant identified specie	1206:1240	Parabacteroides distasonis the most abundant identified specie	1179:1240	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	6	24	theme	obtained	946:953	arg1	results					955:961	The obtained results	942:961	The obtained results	942:961	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	3	25	used	used	538:541	arg2	model					502:506	an in vitro model	490:506	an in vitro model of the human distal colon	490:532	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	0	26	theme	human	125:129	arg1	colon					138:142	the human distal colon	121:142	the human distal colon	121:142	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	8	27	theme	fermentation	1448:1459	arg1	assays					1461:1466	the fermentation assays	1444:1466	the fermentation assays with both substrates	1444:1487	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	2	28	theme	throughput	343:352	arg1	sequencing					354:363	the prebiotic effect throughput sequencing	322:363	the prebiotic effect throughput sequencing	322:363	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	6	29	theme	H.	1002:1003	arg1	fraction					990:997	the colonic fraction	978:997	the colonic fraction of H. elongata	978:1012	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	2	30	theme	prebiotic	326:334	arg1	sequencing					354:363	the prebiotic effect throughput sequencing	322:363	the prebiotic effect throughput sequencing	322:363	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	1	31	theme	carbohydrates	236:248	arg1	effect					218:223	the potential prebiotic effect	194:223	the potential prebiotic effect of seaweed carbohydrates	194:248	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	9	32	theme	short-fatty	1507:1517	arg1	production					1524:1533	the short-fatty acid production	1503:1533	the short-fatty acid production	1503:1533	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	4	33	theme	whole	659:663	arg1	seaweed					665:671	The whole seaweed	655:671	The whole seaweed	655:671	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	11	34	theme	prebiotic	1888:1896	arg1	character					1898:1906	the prebiotic character	1884:1906	the prebiotic character of H. elongata	1884:1921	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	9	35	dep	H.	1594:1595	arg1	elongata					1597:1604	H. elongata	1594:1604	H. elongata	1594:1604	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	5	36	theme	amplicon	879:886	arg1	sequencing					888:897	rRNA amplicon sequencing	874:897	rRNA amplicon sequencing	874:897	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	7	37	theme	Selective	1243:1251	arg1	use					1253:1255	Selective use	1243:1255	Selective use of inulin by P. distasonis	1243:1282	Selective use of inulin by P. distasonis is, therefore, reported by the first time.					
35651022	3	38	theme	first	565:569	arg1	time					571:574	the first time	561:574	the first time	561:574	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	4	39	theme	mineral	723:729	arg1	composition					731:741	its nutritional and mineral composition	703:741	its nutritional and mineral composition	703:741	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	8	40	with	assays	1461:1466	arg1	substrates					1478:1487	both substrates	1473:1487	both substrates	1473:1487	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	0	41	theme	prebiotic	28:36	arg1	effect					38:43	the potential prebiotic effect	14:43	the potential prebiotic effect of Himanthalia elongata, an Atlantic brown	14:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	9	42	theme	maximal	1536:1542	arg1	concentration					1544:1556	maximal concentration	1536:1556	maximal concentration	1536:1556	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	9	42	theme	maximal	1536:1542	arg1	56.11 ± 20.48 mM					1559:1574	56.11 ± 20.48 mM	1559:1574	56.11 ± 20.48 mM	1559:1574	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	5	43	theme	prebiotic	803:811	arg1	effect					813:818	The prebiotic effect	799:818	The prebiotic effect	799:818	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	1	44	theme	whole	271:275	arg1	seaweeds					277:284	the whole seaweeds	267:284	the whole seaweeds	267:284	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	3	45	theme	potential	581:589	arg1	effect					601:606	the potential prebiotic effect	577:606	the potential prebiotic effect of a brown whole seaweed Himanthalia elongata	577:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	5	46	theme	fatty	921:925	arg1	acid					927:930	short-chain fatty acid	909:930	short-chain fatty acid analysis	909:939	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	4	47	theme	nutritional	707:717	arg1	composition					731:741	its nutritional and mineral composition	703:741	its nutritional and mineral composition	703:741	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	6	48	used	used	1131:1134	arg2	inulin					1120:1125	inulin	1120:1125	inulin	1120:1125	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	8	49	from	differences	1364:1374	arg1	Lactobacillus					1424:1436	Lactobacillus	1424:1436	Lactobacillus	1424:1436	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	8	49	from	differences	1364:1374	arg1	population					1395:1404	Bifidobacterium population	1379:1404	Bifidobacterium population	1379:1404	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	6	50	theme	abundant	1215:1222	arg1	specie					1235:1240	the most abundant identified specie	1206:1240	Parabacteroides distasonis the most abundant identified specie	1179:1240	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	1	51	theme	prebiotic	208:216	arg1	effect					218:223	the potential prebiotic effect	194:223	the potential prebiotic effect of seaweed carbohydrates	194:248	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	4	52	theme	gastrointestinal	771:786	arg1	digestion					788:796	the entire gastrointestinal digestion	760:796	the entire gastrointestinal digestion	760:796	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	11	53	theme	Nutrition	2050:2058	arg1	area					2042:2045	the area	2038:2045	the area of Nutrition and Food Chemistry	2038:2077	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	3	54	theme	Himanthalia	633:643	arg1	elongata					645:652	a brown whole seaweed Himanthalia elongata	611:652	a brown whole seaweed Himanthalia elongata	611:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	6	55	theme	specie	1086:1091	arg1	ovatus					1104:1109	the specie Bacteoides ovatus	1082:1109	the specie Bacteoides ovatus	1082:1109	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	3	56	theme	whole	619:623	arg1	elongata					645:652	a brown whole seaweed Himanthalia elongata	611:652	a brown whole seaweed Himanthalia elongata	611:652	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	9	57	theme	fermentation	1618:1629	arg1	24 h					1610:1613	24 h	1610:1613	24 h of fermentation	1610:1629	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	0	58	theme	in	103:104	arg1	model					112:116	an in vitro model	100:116	an in vitro model of the human distal colon	100:142	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	3	59	theme	in	493:494	arg1	model					502:506	an in vitro model	490:506	an in vitro model of the human distal colon	490:532	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	11	60	theme	new	1989:1991	arg1	opportunities					1993:2005	new opportunities	1989:2005	new opportunities of research and application	1989:2033	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	7	61	theme	first	1315:1319	arg1	time					1321:1324	the first time	1311:1324	the first time	1311:1324	Selective use of inulin by P. distasonis is, therefore, reported by the first time.					
35651022	3	62	theme	distal	521:526	arg1	colon					528:532	the human distal colon	511:532	the human distal colon	511:532	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	1	63	theme	different	165:173	arg1	studies					175:181	different studies	165:181	different studies	165:181	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
35651022	9	64	theme	total	1650:1654	arg1	production					1661:1670	total acid production	1650:1670	total acid production	1650:1670	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	8	65	theme	Bifidobacterium	1379:1393	arg1	population					1395:1404	Bifidobacterium population	1379:1404	Bifidobacterium population	1379:1404	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	6	66	used	used	1018:1021	arg2	fraction					990:997	the colonic fraction	978:997	the colonic fraction of H. elongata	978:1012	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	0	67	theme	distal	131:136	arg1	colon					138:142	the human distal colon	121:142	the human distal colon	121:142	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	5	68	theme	microbial	841:849	arg1	modulation					851:860	the microbial modulation	837:860	the microbial modulation	837:860	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	3	69	dep	in	493:494	arg1	vitro					496:500	vitro	496:500	vitro	496:500	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	0	70	theme	Atlantic	73:80	arg1	brown					82:86	an Atlantic brown	70:86	an Atlantic brown	70:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	0	71	dep	in	103:104	arg1	vitro					106:110	vitro	106:110	vitro	106:110	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	9	72	theme	assay	1704:1708	arg1	48 h					1696:1699	48 h	1696:1699	48 h of assay	1696:1708	Regarding to the short-fatty acid production, maximal concentration, 56.11 ± 20.48 mM, was achieved for H. elongata, at 24 h of fermentation whereas for inulin total acid production was 93.66 ± 21.82 mM at 48 h of assay.					
35651022	8	73	from	decrease	1412:1419	arg1	Lactobacillus					1424:1436	Lactobacillus	1424:1436	Lactobacillus	1424:1436	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	8	73	from	decrease	1412:1419	arg1	population					1395:1404	Bifidobacterium population	1379:1404	Bifidobacterium population	1379:1404	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	7	74	theme	inulin	1260:1265	arg1	use					1253:1255	Selective use	1243:1255	Selective use of inulin by P. distasonis	1243:1282	Selective use of inulin by P. distasonis is, therefore, reported by the first time.					
35651022	2	75	theme	bacterial	457:465	arg1	changes					467:473	bacterial changes	457:473	bacterial changes	457:473	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	2	76	theme	effect	336:341	arg1	sequencing					354:363	the prebiotic effect throughput sequencing	322:363	the prebiotic effect throughput sequencing	322:363	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	0	77	theme	potential	18:26	arg1	effect					38:43	the potential prebiotic effect	14:43	the potential prebiotic effect of Himanthalia elongata, an Atlantic brown	14:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	5	78	theme	rRNA	874:877	arg1	sequencing					888:897	rRNA amplicon sequencing	874:897	rRNA amplicon sequencing	874:897	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	6	79	theme	colonic	982:988	arg1	fraction					990:997	the colonic fraction	978:997	the colonic fraction of H. elongata	978:1012	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	10	80	theme	tested	1816:1821	arg1	substrates					1823:1832	the two tested substrates	1808:1832	the two tested substrates	1808:1832	The metabolic pathways associated with bacterial genera were not significantly different between the two tested substrates.					
35651022	6	81	dep	H.	1002:1003	arg1	elongata					1005:1012	H. elongata	1002:1012	H. elongata	1002:1012	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	0	82	theme	effect	38:43	arg1	Evaluation					0:9	Evaluation	0:9	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown	0:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	0	83	dep	Himanthalia	48:58	arg1	elongata					60:67	Himanthalia elongata, an Atlantic brown	48:86	elongata	60:67	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	0	83	dep	Himanthalia	48:58	arg1	brown					82:86	an Atlantic brown	70:86	an Atlantic brown	70:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	0	84	theme	Himanthalia	48:58	arg1	effect					38:43	the potential prebiotic effect	14:43	the potential prebiotic effect of Himanthalia elongata, an Atlantic brown	14:86	Evaluation of the potential prebiotic effect of Himanthalia elongata, an Atlantic brown seaweed, in an in vitro model of the human distal colon.					
35651022	2	85	theme	published	411:419	arg1	works					421:425	the published works	407:425	the published works	407:425	In addition, the prebiotic effect throughput sequencing remains poorly investigated since most of the published works used qPCR or FISH to estimate bacterial changes.					
35651022	4	86	theme	composition	731:741	arg1	basis					694:698	basis	694:698	basis of its nutritional and mineral composition	694:741	The whole seaweed was characterized in basis of its nutritional and mineral composition and submitted to the entire gastrointestinal digestion.					
35651022	5	87	theme	short-chain	909:919	arg1	acid					927:930	short-chain fatty acid	909:930	short-chain fatty acid analysis	909:939	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	3	88	theme	colon	528:532	arg1	model					502:506	an in vitro model	490:506	an in vitro model of the human distal colon	490:532	In this work, an in vitro model of the human distal colon was used to determine, for the first time, the potential prebiotic effect of a brown whole seaweed Himanthalia elongata.					
35651022	6	89	theme	Bacteroides	1042:1052	arg1	genus					1054:1058	the Bacteroides genus	1038:1058	the Bacteroides genus	1038:1058	The obtained results indicated that the colonic fraction of H. elongata was used selectively by the Bacteroides genus, more specifically by the specie Bacteoides ovatus, whereas inulin was used mainly by the Parabacteroides genus, being Parabacteroides distasonis the most abundant identified specie.					
35651022	8	90	theme	qPCR	1327:1330	arg1	analysis					1332:1339	qPCR analysis	1327:1339	qPCR analysis	1327:1339	qPCR analysis shown no significative differences in Bifidobacterium population and a decrease in Lactobacillus along the fermentation assays with both substrates.					
35651022	5	91	theme	acid	927:930	arg1	analysis					932:939	short-chain fatty acid analysis	909:939	short-chain fatty acid analysis	909:939	The prebiotic effect was evaluated by the microbial modulation through 16S rRNA amplicon sequencing, qPCR and short-chain fatty acid analysis.					
35651022	11	92	theme	more	1844:1847	arg1	studies					1849:1855	more studies	1844:1855	more studies	1844:1855	Although more studies are necessary to elucidate the prebiotic character of H. elongata, the results presented in this work are promissory and could open new opportunities of research and application in the area of Nutrition and Food Chemistry.					
35651022	1	93	theme	potential	198:206	arg1	effect					218:223	the potential prebiotic effect	194:223	the potential prebiotic effect of seaweed carbohydrates	194:248	Until now, although different studies have shown the potential prebiotic effect of seaweed carbohydrates, no studies with the whole seaweeds have been carried out.					
34718415	10	0	theme	production	1862:1871	arg1	stages					1842:1847	all stages	1838:1847	all stages of embryonic production	1838:1871	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	6	1	theme	cows	1210:1213	arg1	supplementation					1181:1195	the n-3 or n-6 supplementation	1166:1195	the n-3 or n-6 supplementation of the donor cows	1166:1213	No lipids were different according to the n-3 or n-6 supplementation of the donor cows.					
34718415	3	2	theme	freezing	437:444	arg1	protocols					446:454	the slow freezing protocols	428:454	the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose)	428:503	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	4	3	theme	cow	820:822	arg1	embryos					824:830	cow embryos	820:830	cow embryos	820:830	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	7	4	theme	freezing	1333:1340	arg1	protocols					1342:1350	the slow freezing protocols	1324:1350	the slow freezing protocols	1324:1350	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	2	5	theme	lipid	234:238	arg1	composition					240:250	embryo lipid composition	227:250	embryo lipid composition	227:250	Efforts have been made to optimize embryo lipid composition as it is associated with their quality.					
34718415	3	6	theme	physiological	513:525	arg1	stage					527:531	the physiological stage	509:531	the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	509:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	7	7	theme	donors	1313:1318	arg1	stage					1300:1304	the physiological stage	1282:1304	the physiological stage of the donors and the slow freezing protocols	1282:1350	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	10	8	dep	modulate	1751:1758	arg1	integrating					1826:1836	integrating	1826:1836	integrating all stages of embryonic production	1826:1871	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	10	8	dep	modulate	1751:1758	arg1	modulating					1795:1804	modulating	1795:1804	modulating the lipidome	1795:1817	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	10	9	theme	Further	1719:1725	arg1	studies					1727:1733	Further studies	1719:1733	Further studies	1719:1733	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	10	10	theme	embryo	1760:1765	arg1	quality					1767:1773	embryo quality	1760:1773	embryo quality	1760:1773	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	8	11	theme	lipids	1374:1379	arg1	overabundance					1357:1369	The overabundance	1353:1369	The overabundance of lipids in lactating cow embryos	1353:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	11	theme	lipids	1374:1379	arg1	quality					1430:1436	the resulting lower quality	1410:1436	the resulting lower quality of these embryos	1410:1453	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	11	theme	lipids	1374:1379	arg1	consistent					1459:1468	consistent	1459:1468	consistent	1459:1468	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	7	12	theme	physiological	1286:1298	arg1	stage					1300:1304	the physiological stage	1282:1304	the physiological stage of the donors and the slow freezing protocols	1282:1350	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	10	13	theme	embryonic	1852:1860	arg1	production					1862:1871	embryonic production	1852:1871	embryonic production	1852:1871	Further studies are required to modulate embryo quality and freezability by modulating the lipidome and by integrating all stages of embryonic production.					
34718415	8	14	with	consistent	1459:1468	arg1	rate					1495:1498	the lower pregnancy rate	1475:1498	the lower pregnancy rate observed in cows compared to heifers	1475:1535	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	9	15	theme	glycol	1583:1588	arg1	freezing					1598:1605	ethylene glycol sucrose freezing	1574:1605	ethylene glycol sucrose freezing	1574:1605	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	4	16	theme	heifer	844:849	arg1	embryos					851:857	heifer embryos	844:857	heifer embryos	844:857	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	8	17	theme	lactating	1384:1392	arg1	embryos					1398:1404	lactating cow embryos	1384:1404	lactating cow embryos	1384:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	18	theme	nulliparous	547:557	arg1	heifers					559:565	nulliparous heifers	547:565	nulliparous heifers	547:565	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	8	19	from	lipids	1374:1379	arg1	embryos					1398:1404	lactating cow embryos	1384:1404	lactating cow embryos	1384:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	20	theme	donor	540:544	arg1	stage					527:531	the physiological stage	509:531	the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	509:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	20	theme	donor	540:544	arg1	cows					378:381	donor cows	372:381	donor cows (n-3 or n-6 polyunsaturated fatty acids)	372:422	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	20	theme	donor	540:544	arg1	protocols					446:454	the slow freezing protocols	428:454	the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose)	428:503	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	20	theme	donor	540:544	arg1	acids					417:421	n-3 or n-6 polyunsaturated fatty acids	384:421	n-3 or n-6 polyunsaturated fatty acids	384:421	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	1	21	theme	in	128:129	arg1	conditions					145:154	in vitro culture conditions	128:154	in vitro culture conditions that lead to an increase in lipids	128:189	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	0	22	theme	bovine	59:64	arg1	profile†					82:89	the bovine embryonic lipid profile†	55:89	the bovine embryonic lipid profile†	55:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	4	23	from	overabundant	804:815	arg1	embryos					824:830	cow embryos	820:830	cow embryos	820:830	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	1	24	theme	culture	137:143	arg1	conditions					145:154	in vitro culture conditions	128:154	in vitro culture conditions that lead to an increase in lipids	128:189	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	3	25	theme	study	314:318	arg1	objective					296:304	The objective	292:304	The objective of this study	292:318	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	8	26	theme	lower	1424:1428	arg1	consistent					1459:1468	consistent	1459:1468	consistent	1459:1468	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	26	theme	lower	1424:1428	arg1	quality					1430:1436	the resulting lower quality	1410:1436	the resulting lower quality of these embryos	1410:1453	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	4	27	theme	embryos	664:670	arg1	extracts					649:656	Lipid extracts	643:656	Lipid extracts of 97 embryos	643:670	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	0	28	theme	lipid	76:80	arg1	profile†					82:89	the bovine embryonic lipid profile†	55:89	the bovine embryonic lipid profile†	55:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	4	29	theme	liquid	702:707	arg1	spectrometry					745:756	liquid chromatography-high resolution mass spectrometry	702:756	liquid chromatography-high resolution mass spectrometry	702:756	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	5	30	theme	modulated	1037:1045	arg1	lipids					1047:1052	the significantly modulated lipids	1019:1052	the significantly modulated lipids	1019:1052	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	31	theme	ethylene	918:925	arg1	glycol					927:932	ethylene glycol	918:932	ethylene glycol sucrose protocol	918:949	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	8	32	theme	embryos	1447:1453	arg1	overabundance					1357:1369	The overabundance	1353:1369	The overabundance of lipids in lactating cow embryos	1353:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	32	theme	embryos	1447:1453	arg1	quality					1430:1436	the resulting lower quality	1410:1436	the resulting lower quality of these embryos	1410:1453	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	32	theme	embryos	1447:1453	arg1	consistent					1459:1468	consistent	1459:1468	consistent	1459:1468	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	33	theme	cows	378:381	arg1	supplementation					353:367	the diet supplementation	344:367	the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	344:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	7	34	theme	lipid	1245:1249	arg1	profile					1251:1257	the embryonic lipid profile	1231:1257	the embryonic lipid profile	1231:1257	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	3	35	theme	fatty	411:415	arg1	cows					378:381	donor cows	372:381	donor cows (n-3 or n-6 polyunsaturated fatty acids)	372:422	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	35	theme	fatty	411:415	arg1	acids					417:421	n-3 or n-6 polyunsaturated fatty acids	384:421	n-3 or n-6 polyunsaturated fatty acids	384:421	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	1	36	theme	Embryo	92:97	arg1	profile					105:111	Embryo lipid profile	92:111	Embryo lipid profile	92:111	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	3	37	theme	lactating	583:591	arg1	cows					593:596	primiparous lactating cows	571:596	primiparous lactating cows	571:596	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	0	38	theme	factors	21:27	arg1	Effects					0:6	Effects	0:6	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†	0:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	3	39	theme	diet	348:351	arg1	supplementation					353:367	the diet supplementation	344:367	the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	344:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	8	40	theme	pregnancy	1485:1493	arg1	rate					1495:1498	the lower pregnancy rate	1475:1498	the lower pregnancy rate observed in cows compared to heifers	1475:1535	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	0	41	theme	freezing	33:40	arg1	protocols					42:50	freezing protocols	33:50	freezing protocols	33:50	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	5	42	theme	glycerophosphate	971:986	arg1	32:1					991:994	32:1	991:994	32:1	991:994	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	42	theme	glycerophosphate	971:986	arg1	PA					988:989	a single glycerophosphate PA	962:989	a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids	962:1052	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	43	used	used	1122:1125	arg2	protocol					1110:1117	glycerol-trehalose protocol	1091:1117	glycerol-trehalose protocol	1091:1117	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	4	44	theme	resolution	729:738	arg1	spectrometry					745:756	liquid chromatography-high resolution mass spectrometry	702:756	liquid chromatography-high resolution mass spectrometry	702:756	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	3	45	theme	glycol	466:471	arg1	sucrose					473:479	ethylene glycol sucrose	457:479	ethylene glycol sucrose	457:479	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	5	46	theme	sucrose	934:940	arg1	protocol					942:949	ethylene glycol sucrose protocol	918:949	ethylene glycol sucrose protocol	918:949	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	3	47	theme	protocols	446:454	arg1	supplementation					353:367	the diet supplementation	344:367	the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	344:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	8	48	located	observed	1500:1507	arg1	cows					1512:1515	cows	1512:1515	cows compared to heifers	1512:1535	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	48	located	observed	1500:1507	arg2	rate					1495:1498	the lower pregnancy rate	1475:1498	the lower pregnancy rate observed in cows compared to heifers	1475:1535	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	49	theme	lipid	628:632	arg1	profile					634:640	the bovine embryo lipid profile	610:640	the bovine embryo lipid profile	610:640	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	50	theme	slow	432:435	arg1	protocols					446:454	the slow freezing protocols	428:454	the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose)	428:503	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	9	51	theme	ethylene	1574:1581	arg1	glycol					1583:1588	ethylene glycol	1574:1588	ethylene glycol sucrose freezing	1574:1605	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	3	52	theme	bovine	614:619	arg1	profile					634:640	the bovine embryo lipid profile	610:640	the bovine embryo lipid profile	610:640	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	6	53	theme	donor	1204:1208	arg1	cows					1210:1213	the donor cows	1200:1213	the donor cows	1200:1213	No lipids were different according to the n-3 or n-6 supplementation of the donor cows.					
34718415	9	54	theme	sucrose	1590:1596	arg1	freezing					1598:1605	ethylene glycol sucrose freezing	1574:1605	ethylene glycol sucrose freezing	1574:1605	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	3	55	theme	ethylene	457:464	arg1	sucrose					473:479	ethylene glycol sucrose	457:479	ethylene glycol sucrose	457:479	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	7	56	theme	protocols	1342:1350	arg1	stage					1300:1304	the physiological stage	1282:1304	the physiological stage of the donors and the slow freezing protocols	1282:1350	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	8	57	from	overabundance	1357:1369	arg1	embryos					1398:1404	lactating cow embryos	1384:1404	lactating cow embryos	1384:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	58	dep	stage	527:531	arg1	heifers					559:565	nulliparous heifers	547:565	nulliparous heifers	547:565	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	58	dep	stage	527:531	arg1	cows					593:596	primiparous lactating cows	571:596	primiparous lactating cows	571:596	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	7	59	theme	slow	1328:1331	arg1	protocols					1342:1350	the slow freezing protocols	1324:1350	the slow freezing protocols	1324:1350	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	3	60	theme	stage	527:531	arg1	supplementation					353:367	the diet supplementation	344:367	the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows)	344:597	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	1	61	theme	lipid	99:103	arg1	profile					105:111	Embryo lipid profile	92:111	Embryo lipid profile	92:111	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	0	62	from	Effects	0:6	arg1	profile†					82:89	the bovine embryonic lipid profile†	55:89	the bovine embryonic lipid profile†	55:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	9	63	theme	slow	1675:1678	arg1	freezing					1680:1687	the slow freezing	1671:1687	the slow freezing of in vitro-produced embryos	1671:1716	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	8	64	theme	cow	1394:1396	arg1	embryos					1398:1404	lactating cow embryos	1384:1404	lactating cow embryos	1384:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	2	65	theme	embryo	227:232	arg1	composition					240:250	embryo lipid composition	227:250	embryo lipid composition	227:250	Efforts have been made to optimize embryo lipid composition as it is associated with their quality.					
34718415	1	66	from	increase	172:179	arg1	lipids					184:189	lipids	184:189	lipids	184:189	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	9	67	from	freezing	1680:1687	arg1	embryos					1710:1716	vitro-produced embryos	1695:1716	vitro-produced embryos	1695:1716	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	4	68	theme	Lipid	643:647	arg1	extracts					649:656	Lipid extracts	643:656	Lipid extracts of 97 embryos	643:670	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	4	69	from	embryos	824:830	arg1	overabundant					804:815	overabundant	804:815	overabundant	804:815	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	9	70	theme	vitro-produced	1695:1708	arg1	embryos					1710:1716	vitro-produced embryos	1695:1716	vitro-produced embryos	1695:1716	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	8	71	theme	resulting	1414:1422	arg1	consistent					1459:1468	consistent	1459:1468	consistent	1459:1468	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	71	theme	resulting	1414:1422	arg1	quality					1430:1436	the resulting lower quality	1410:1436	the resulting lower quality of these embryos	1410:1453	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	72	from	embryos	1398:1404	arg1	overabundance					1357:1369	The overabundance	1353:1369	The overabundance of lipids in lactating cow embryos	1353:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	72	from	embryos	1398:1404	arg1	quality					1430:1436	the resulting lower quality	1410:1436	the resulting lower quality of these embryos	1410:1453	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	8	72	from	embryos	1398:1404	arg1	consistent					1459:1468	consistent	1459:1468	consistent	1459:1468	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	0	73	theme	embryonic	66:74	arg1	profile†					82:89	the bovine embryonic lipid profile†	55:89	the bovine embryonic lipid profile†	55:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	8	74	from	quality	1430:1436	arg1	embryos					1398:1404	lactating cow embryos	1384:1404	lactating cow embryos	1384:1404	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	5	75	theme	lipids	1047:1052	arg1	lipids					1047:1052	the significantly modulated lipids	1019:1052	the significantly modulated lipids	1019:1052	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	75	theme	lipids	1047:1052	arg1	%					1014:1014	27.3%	1010:1014	27.3% of the significantly modulated lipids	1010:1052	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	76	theme	differential	870:881	arg1	lipids					883:888	105 differential lipids	866:888	105 differential lipids	866:888	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	7	77	theme	embryonic	1235:1243	arg1	profile					1251:1257	the embryonic lipid profile	1231:1257	the embryonic lipid profile	1231:1257	In conclusion, the embryonic lipid profile was mainly affected by the physiological stage of the donors and the slow freezing protocols.					
34718415	0	78	theme	donor	15:19	arg1	factors					21:27	the donor factors	11:27	the donor factors	11:27	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	3	79	dep	protocols	446:454	arg1	sucrose					473:479	ethylene glycol sucrose	457:479	ethylene glycol sucrose	457:479	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	79	dep	protocols	446:454	arg1	glycerol-trehalose					485:502	glycerol-trehalose	485:502	glycerol-trehalose	485:502	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	8	80	theme	lower	1479:1483	arg1	rate					1495:1498	the lower pregnancy rate	1475:1498	the lower pregnancy rate observed in cows compared to heifers	1475:1535	The overabundance of lipids in lactating cow embryos and the resulting lower quality of these embryos are consistent with the lower pregnancy rate observed in cows compared to heifers.					
34718415	3	81	theme	primiparous	571:581	arg1	cows					593:596	primiparous lactating cows	571:596	primiparous lactating cows	571:596	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	1	82	dep	in	128:129	arg1	vitro					131:135	vitro	131:135	vitro	131:135	Embryo lipid profile is affected by in vitro culture conditions that lead to an increase in lipids.					
34718415	3	83	theme	donor	372:376	arg1	cows					378:381	donor cows	372:381	donor cows (n-3 or n-6 polyunsaturated fatty acids)	372:422	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	83	theme	donor	372:376	arg1	acids					417:421	n-3 or n-6 polyunsaturated fatty acids	384:421	n-3 or n-6 polyunsaturated fatty acids	384:421	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	84	theme	polyunsaturated	395:409	arg1	cows					378:381	donor cows	372:381	donor cows (n-3 or n-6 polyunsaturated fatty acids)	372:422	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	3	84	theme	polyunsaturated	395:409	arg1	acids					417:421	n-3 or n-6 polyunsaturated fatty acids	384:421	n-3 or n-6 polyunsaturated fatty acids	384:421	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	0	85	theme	protocols	42:50	arg1	Effects					0:6	Effects	0:6	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†	0:89	Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile†.					
34718415	5	86	theme	single	964:969	arg1	32:1					991:994	32:1	991:994	32:1	991:994	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	86	theme	single	964:969	arg1	PA					988:989	a single glycerophosphate PA	962:989	a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids	962:1052	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	87	theme	glycerol-trehalose	1091:1108	arg1	protocol					1110:1117	glycerol-trehalose protocol	1091:1117	glycerol-trehalose protocol	1091:1117	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	5	88	theme	glycol	927:932	arg1	protocol					942:949	ethylene glycol sucrose protocol	918:949	ethylene glycol sucrose protocol	918:949	Among 105 differential lipids, 72 were overabundant after ethylene glycol sucrose protocol, including a single glycerophosphate PA(32:1) representing 27.3% of the significantly modulated lipids, suggesting that it is degraded when glycerol-trehalose protocol is used.					
34718415	4	89	theme	chromatography-high	709:727	arg1	spectrometry					745:756	liquid chromatography-high resolution mass spectrometry	702:756	liquid chromatography-high resolution mass spectrometry	702:756	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
34718415	9	90	theme	glycerol-trehalose	1545:1562	arg1	protocol					1564:1571	glycerol-trehalose protocol	1545:1571	glycerol-trehalose protocol	1545:1571	Unlike glycerol-trehalose protocol, ethylene glycol sucrose freezing allowed to preserve glycerophospholipids, potentially improving the slow freezing of in vitro-produced embryos.					
34718415	3	91	theme	embryo	621:626	arg1	profile					634:640	the bovine embryo lipid profile	610:640	the bovine embryo lipid profile	610:640	The objective of this study was to evaluate whether the diet supplementation of donor cows (n-3 or n-6 polyunsaturated fatty acids), or the slow freezing protocols (ethylene glycol sucrose vs. glycerol-trehalose), or the physiological stage of the donor (nulliparous heifers vs. primiparous lactating cows) may impact the bovine embryo lipid profile.					
34718415	4	92	theme	mass	740:743	arg1	spectrometry					745:756	liquid chromatography-high resolution mass spectrometry	702:756	liquid chromatography-high resolution mass spectrometry	702:756	Lipid extracts of 97 embryos were individually analyzed by liquid chromatography-high resolution mass spectrometry, highlighting 246 lipids, including 85% being overabundant in cow embryos compared to heifer embryos.					
37000586	9	0	theme	chitosan	1375:1382	arg1	amounts					1364:1370	equal amounts	1358:1370	equal amounts of chitosan and gelatin	1358:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	0	theme	chitosan	1375:1382	arg1	gelatin					1388:1394	gelatin	1388:1394	gelatin	1388:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	0	theme	chitosan	1375:1382	arg1	chitosan					1375:1382	chitosan	1375:1382	chitosan	1375:1382	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	6	1	theme	fibroblast	945:954	arg1	cells					956:960	fibroblast cells	945:960	fibroblast cells	945:960	The cell proliferation and viability of the samples were quantified via MTT assay using fibroblast cells.					
37000586	8	2	theme	strong	1257:1262	arg1	correlation					1264:1274	a strong correlation	1255:1274	a strong correlation between the experimental data and molecular dynamics simulations	1255:1339	The results demonstrated a strong correlation between the experimental data and molecular dynamics simulations.					
37000586	4	3	theme	wound	740:744	arg1	scaffold					746:753	a composite skin-tissue wound scaffold	716:753	a composite skin-tissue wound scaffold with five different polymer ratios	716:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	9	4	theme	kcal	1509:1512	arg1	mol-1					1514:1518	149 kcal mol-1	1505:1518	149 kcal mol-1 for fibronectin	1505:1534	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	1	5	theme	experimental	319:330	arg1	assay					332:336	an experimental assay	316:336	an experimental assay	316:336	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	0	6	theme	substrate	108:116	arg1	biocompatibility					78:93	the biocompatibility	74:93	the biocompatibility of polymeric substrate for skin-tissue-engineering applications	74:157	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	0	6	theme	substrate	108:116	arg1	simulation					59:68	the protein adhesion simulation	38:68	the protein adhesion simulation	38:68	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	7	7	theme	higher	1151:1156	arg1	percentage					1166:1175	a higher gelatin percentage	1149:1175	a higher gelatin percentage in the scaffold	1149:1191	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	6	8	theme	cell	861:864	arg1	proliferation					866:878	cell proliferation	861:878	cell proliferation	861:878	The cell proliferation and viability of the samples were quantified via MTT assay using fibroblast cells.					
37000586	3	9	theme	scaffold	583:590	arg1	biocompatibility					551:566	the biocompatibility	547:566	the biocompatibility of a composite scaffold	547:590	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	3	9	theme	scaffold	583:590	arg1	simulations					619:629	the molecular dynamics simulations	596:629	the molecular dynamics simulations of protein adhesion	596:649	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	0	10	theme	polymeric	98:106	arg1	substrate					108:116	polymeric substrate	98:116	polymeric substrate	98:116	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	4	11	with	scaffold	746:753	arg1	ratios					783:788	five different polymer ratios	760:788	five different polymer ratios	760:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	7	12	theme	gelatin	1158:1164	arg1	percentage					1166:1175	a higher gelatin percentage	1149:1175	a higher gelatin percentage in the scaffold	1149:1191	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	13	theme	simulations	999:1009	arg1	series					970:975	a series	968:975	a series of molecular dynamics simulations	968:1009	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	4	14	theme	different	765:773	arg1	ratios					783:788	five different polymer ratios	760:788	five different polymer ratios	760:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	0	15	theme	skin-tissue-engineering	122:144	arg1	applications					146:157	skin-tissue-engineering applications	122:157	skin-tissue-engineering applications	122:157	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	7	16	from	decrease	1204:1211	arg1	porosity					1220:1227	the porosity	1216:1227	the porosity	1216:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	9	17	theme	kcal	1469:1472	arg1	mol-1					1474:1478	239 kcal mol-1	1465:1478	239 kcal mol-1 for collagen type I	1465:1498	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	18	theme	collagen	1484:1491	arg1	type					1493:1496	collagen type I	1484:1498	collagen type I	1484:1498	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	1	19	theme	polymeric	209:217	arg1	scaffolds					219:227	polymeric scaffolds	209:227	polymeric scaffolds	209:227	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	5	20	theme	polymeric	796:804	arg1	blend					806:810	This polymeric blend	791:810	This polymeric blend	791:810	This polymeric blend has not been simulated for protein adhesion.					
37000586	10	21	theme	weakest	1686:1692	arg1	energy					1703:1708	the weakest adhesion energy	1682:1708	the weakest adhesion energy	1682:1708	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	7	22	dep	I.	1137:1138	arg1	leads					1193:1197	leads	1193:1197	leads to a decrease in the porosity	1193:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	23	theme	molecular	980:988	arg1	simulations					999:1009	molecular dynamics simulations	980:1009	molecular dynamics simulations	980:1009	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	3	24	theme	composite	573:581	arg1	scaffold					583:590	a composite scaffold	571:590	a composite scaffold	571:590	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	1	25	theme	scaffolds	219:227	arg1	properties					195:204	the protein adhesion properties	174:204	the protein adhesion properties of polymeric scaffolds	174:227	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	10	26	theme	3 	1632:1633	arg1	ratios					1622:1627	gelatin-to-chitosan ratios	1602:1627	gelatin-to-chitosan ratios of 3 	1602:1633	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	6	27	theme	MTT	929:931	arg1	assay					933:937	MTT assay	929:937	MTT assay using fibroblast cells	929:960	The cell proliferation and viability of the samples were quantified via MTT assay using fibroblast cells.					
37000586	7	28	theme	dynamics	990:997	arg1	simulations					999:1009	molecular dynamics simulations	980:1009	molecular dynamics simulations	980:1009	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	3	29	theme	dynamics	610:617	arg1	simulations					619:629	the molecular dynamics simulations	596:629	the molecular dynamics simulations of protein adhesion	596:649	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	3	30	theme	current	469:475	arg1	study					477:481	The current study	465:481	The current study	465:481	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	10	31	theme	lowest	1656:1661	arg1	viability					1668:1676	the lowest cell viability	1652:1676	the lowest cell viability	1652:1676	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	1	32	theme	computational	237:249	arg1	simulations					251:261	computational simulations	237:261	computational simulations	237:261	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	9	33	theme	gelatin	1388:1394	arg1	amounts					1364:1370	equal amounts	1358:1370	equal amounts of chitosan and gelatin	1358:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	33	theme	gelatin	1388:1394	arg1	gelatin					1388:1394	gelatin	1388:1394	gelatin	1388:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	33	theme	gelatin	1388:1394	arg1	chitosan					1375:1382	chitosan	1375:1382	chitosan	1375:1382	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	7	34	theme	collagen	1123:1130	arg1	proteins					1095:1102	two prominent extracellular matrix proteins	1060:1102	two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1060:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	34	theme	collagen	1123:1130	arg1	type					1132:1135	collagen type	1123:1135	collagen type	1123:1135	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	10	35	with	samples	1589:1595	arg1	ratios					1622:1627	gelatin-to-chitosan ratios	1602:1627	gelatin-to-chitosan ratios of 3 	1602:1633	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	8	36	theme	molecular	1310:1318	arg1	simulations					1329:1339	molecular dynamics simulations	1310:1339	molecular dynamics simulations	1310:1339	The results demonstrated a strong correlation between the experimental data and molecular dynamics simulations.					
37000586	10	37	theme	gelatin-to-chitosan	1602:1620	arg1	ratios					1622:1627	gelatin-to-chitosan ratios	1602:1627	gelatin-to-chitosan ratios of 3 	1602:1633	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	38	dep	samples	1580:1586	arg1	 1					1635:1636	 1	1635:1636	 1	1635:1636	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	38	dep	samples	1580:1586	arg1	samples					1589:1595	samples	1589:1595	other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 	1574:1643	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	38	dep	samples	1580:1586	arg1	1 					1642:1643	1 	1642:1643	1 	1642:1643	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	39	from	evident	1563:1569	arg1	samples					1580:1586	other samples	1574:1586	other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 	1574:1643	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	3	40	theme	molecular	600:608	arg1	simulations					619:629	the molecular dynamics simulations	596:629	the molecular dynamics simulations of protein adhesion	596:649	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	4	41	theme	skin-tissue	728:738	arg1	scaffold					746:753	a composite skin-tissue wound scaffold	716:753	a composite skin-tissue wound scaffold with five different polymer ratios	716:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	0	42	theme	protein	42:48	arg1	simulation					59:68	the protein adhesion simulation	38:68	the protein adhesion simulation	38:68	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	10	43	theme	adhesion	1694:1701	arg1	energy					1703:1708	the weakest adhesion energy	1682:1708	the weakest adhesion energy	1682:1708	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	3	44	theme	adhesion	642:649	arg1	biocompatibility					551:566	the biocompatibility	547:566	the biocompatibility of a composite scaffold	547:590	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	3	44	theme	adhesion	642:649	arg1	simulations					619:629	the molecular dynamics simulations	596:629	the molecular dynamics simulations of protein adhesion	596:649	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	8	45	theme	experimental	1288:1299	arg1	data					1301:1304	the experimental data	1284:1304	the experimental data	1284:1304	The results demonstrated a strong correlation between the experimental data and molecular dynamics simulations.					
37000586	10	46	theme	cell	1663:1666	arg1	viability					1668:1676	the lowest cell viability	1652:1676	the lowest cell viability	1652:1676	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	9	47	theme	mol-1	1474:1478	arg1	energy					1454:1459	the strongest adhesion energy	1431:1459	the strongest adhesion energy	1431:1459	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	47	theme	mol-1	1474:1478	arg1	viability					1417:1425	the highest cell viability	1400:1425	the highest cell viability	1400:1425	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	47	theme	mol-1	1474:1478	arg1	mol-1					1514:1518	149 kcal mol-1	1505:1518	149 kcal mol-1 for fibronectin	1505:1534	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	48	theme	highest	1404:1410	arg1	viability					1417:1425	the highest cell viability	1400:1425	the highest cell viability	1400:1425	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	49	theme	adhesion	1445:1452	arg1	energy					1454:1459	the strongest adhesion energy	1431:1459	the strongest adhesion energy	1431:1459	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	7	50	theme	prominent	1064:1072	arg1	fibronectin					1106:1116	fibronectin	1106:1116	fibronectin	1106:1116	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	50	theme	prominent	1064:1072	arg1	proteins					1095:1102	two prominent extracellular matrix proteins	1060:1102	two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1060:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	50	theme	prominent	1064:1072	arg1	type					1132:1135	collagen type	1123:1135	collagen type	1123:1135	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	2	51	theme	experimental	444:455	arg1	assays					457:462	experimental assays	444:462	experimental assays	444:462	This prediction can be highly beneficial since it can cut costs and the time it takes for experimental assays.					
37000586	5	52	theme	protein	839:845	arg1	adhesion					847:854	protein adhesion	839:854	protein adhesion	839:854	This polymeric blend has not been simulated for protein adhesion.					
37000586	9	53	theme	cell	1412:1415	arg1	viability					1417:1425	the highest cell viability	1400:1425	the highest cell viability	1400:1425	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	6	54	theme	samples	901:907	arg1	viability					884:892	viability	884:892	viability	884:892	The cell proliferation and viability of the samples were quantified via MTT assay using fibroblast cells.					
37000586	6	54	theme	samples	901:907	arg1	proliferation					866:878	cell proliferation	861:878	cell proliferation	861:878	The cell proliferation and viability of the samples were quantified via MTT assay using fibroblast cells.					
37000586	7	55	theme	extracellular	1074:1086	arg1	fibronectin					1106:1116	fibronectin	1106:1116	fibronectin	1106:1116	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	55	theme	extracellular	1074:1086	arg1	proteins					1095:1102	two prominent extracellular matrix proteins	1060:1102	two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1060:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	55	theme	extracellular	1074:1086	arg1	type					1132:1135	collagen type	1123:1135	collagen type	1123:1135	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	9	56	contain	had	1396:1398	arg1	sample					1346:1351	The sample	1342:1351	The sample with equal amounts of chitosan and gelatin	1342:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	56	contain	had	1396:1398	arg2	viability					1417:1425	the highest cell viability	1400:1425	the highest cell viability	1400:1425	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	56	contain	had	1396:1398	arg2	energy					1454:1459	the strongest adhesion energy	1431:1459	the strongest adhesion energy	1431:1459	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	56	contain	had	1396:1398	arg2	mol-1					1514:1518	149 kcal mol-1	1505:1518	149 kcal mol-1 for fibronectin	1505:1534	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	0	57	theme	adhesion	50:57	arg1	simulation					59:68	the protein adhesion simulation	38:68	the protein adhesion simulation	38:68	Investigating the correlation between the protein adhesion simulation and the biocompatibility of polymeric substrate for skin-tissue-engineering applications.					
37000586	7	58	from	percentage	1166:1175	arg1	scaffold					1184:1191	the scaffold	1180:1191	the scaffold	1180:1191	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	9	59	theme	strongest	1435:1443	arg1	energy					1454:1459	the strongest adhesion energy	1431:1459	the strongest adhesion energy	1431:1459	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	3	60	theme	protein	634:640	arg1	adhesion					642:649	protein adhesion	634:649	protein adhesion	634:649	The current study aims to test the hypothesis that there is a correlation between the biocompatibility of a composite scaffold and the molecular dynamics simulations of protein adhesion.					
37000586	10	61	contain	had	1648:1650	arg2	viability					1668:1676	the lowest cell viability	1652:1676	the lowest cell viability	1652:1676	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	61	contain	had	1648:1650	arg2	energy					1703:1708	the weakest adhesion energy	1682:1708	the weakest adhesion energy	1682:1708	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	10	61	contain	had	1648:1650	arg1	 3					1645:1646	 3	1645:1646	 3	1645:1646	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	7	62	theme	matrix	1088:1093	arg1	fibronectin					1106:1116	fibronectin	1106:1116	fibronectin	1106:1116	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	62	theme	matrix	1088:1093	arg1	proteins					1095:1102	two prominent extracellular matrix proteins	1060:1102	two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1060:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	62	theme	matrix	1088:1093	arg1	type					1132:1135	collagen type	1123:1135	collagen type	1123:1135	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	10	63	from	samples	1580:1586	arg1	evident					1563:1569	evident	1563:1569	evident	1563:1569	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	4	64	theme	polymer	775:781	arg1	ratios					783:788	five different polymer ratios	760:788	five different polymer ratios	760:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	7	65	theme	proteins	1095:1102	arg1	energy					1050:1055	the adhesion energy	1037:1055	the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1037:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	2	66	dep	time	426:429	arg1	it					431:432	it	431:432	it	431:432	This prediction can be highly beneficial since it can cut costs and the time it takes for experimental assays.					
37000586	7	67	theme	adhesion	1041:1048	arg1	energy					1050:1055	the adhesion energy	1037:1055	the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1037:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	4	68	theme	composite	718:726	arg1	scaffold					746:753	a composite skin-tissue wound scaffold	716:753	a composite skin-tissue wound scaffold with five different polymer ratios	716:788	To this end, chitosan and gelatin were selected for fabricating a composite skin-tissue wound scaffold with five different polymer ratios.					
37000586	7	69	dep	fibronectin	1106:1116	arg1	I.					1137:1138	I.	1137:1138	I.	1137:1138	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	10	70	theme	other	1574:1578	arg1	samples					1580:1586	other samples	1574:1586	other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 	1574:1643	This correlation was also evident in other samples: samples with gelatin-to-chitosan ratios of 3 : 1 and 1 : 3 had the lowest cell viability and the weakest adhesion energy, respectively.					
37000586	8	71	theme	dynamics	1320:1327	arg1	simulations					1329:1339	molecular dynamics simulations	1310:1339	molecular dynamics simulations	1310:1339	The results demonstrated a strong correlation between the experimental data and molecular dynamics simulations.					
37000586	1	72	theme	protein	178:184	arg1	properties					195:204	the protein adhesion properties	174:204	the protein adhesion properties of polymeric scaffolds	174:227	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	1	73	theme	scaffolds	299:307	arg1	biocompatibility					279:294	the biocompatibility	275:294	the biocompatibility of scaffolds	275:307	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	9	74	theme	equal	1358:1362	arg1	amounts					1364:1370	equal amounts	1358:1370	equal amounts of chitosan and gelatin	1358:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	74	theme	equal	1358:1362	arg1	gelatin					1388:1394	gelatin	1388:1394	gelatin	1388:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	74	theme	equal	1358:1362	arg1	chitosan					1375:1382	chitosan	1375:1382	chitosan	1375:1382	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	1	75	theme	adhesion	186:193	arg1	properties					195:204	the protein adhesion properties	174:204	the protein adhesion properties of polymeric scaffolds	174:227	Investigating the protein adhesion properties of polymeric scaffolds through computational simulations can predict the biocompatibility of scaffolds before an experimental assay is carried out.					
37000586	9	76	with	sample	1346:1351	arg1	amounts					1364:1370	equal amounts	1358:1370	equal amounts of chitosan and gelatin	1358:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	76	with	sample	1346:1351	arg1	gelatin					1388:1394	gelatin	1388:1394	gelatin	1388:1394	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	9	76	with	sample	1346:1351	arg1	chitosan					1375:1382	chitosan	1375:1382	chitosan	1375:1382	The sample with equal amounts of chitosan and gelatin had the highest cell viability and the strongest adhesion energy, of 239 kcal mol-1 for collagen type I, and 149 kcal mol-1 for fibronectin.					
37000586	7	77	dep	proteins	1095:1102	arg1	fibronectin					1106:1116	fibronectin	1106:1116	fibronectin	1106:1116	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	77	dep	proteins	1095:1102	arg1	proteins					1095:1102	two prominent extracellular matrix proteins	1060:1102	two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity	1060:1227	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
37000586	7	77	dep	proteins	1095:1102	arg1	type					1132:1135	collagen type	1123:1135	collagen type	1123:1135	Then a series of molecular dynamics simulations were performed to measure the adhesion energy of two prominent extracellular matrix proteins - fibronectin, and collagen type I. Besides, a higher gelatin percentage in the scaffold leads to a decrease in the porosity.					
36764345	7	0	theme	dye	1119:1121	arg1	concentration					1123:1135	CR dye concentration	1116:1135	CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion	1116:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	1	1	theme	Nickel	151:156	arg1	oxide					158:162	Nickel oxide	151:162	Nickel oxide	151:162	Nickel oxide nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation.					
36764345	5	2	contain	have	647:650	arg2	content					665:671	a Ni element content	652:671	a Ni element content of 4.65 wt%	652:683	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	5	2	contain	have	647:650	arg1	beads					641:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	4	3	theme	crystalline	518:528	arg1	nature					530:535	crystalline nature	518:535	crystalline nature	518:535	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	7	4	theme	catalyst	1089:1096	arg1	dose					1098:1101	catalyst dose	1089:1101	catalyst dose of 11 mg	1089:1110	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	2	5	theme	@	357:357	arg1	beads					379:383	@AC-NiO nanocomposite beads	357:383	@AC-NiO nanocomposite beads	357:383	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	5	6	theme	NiO	701:703	arg1	diameter					714:721	an average NiO particle diameter	690:721	an average NiO particle diameter of 23 nm	690:730	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	4	7	dep	nature	530:535	arg1	The					514:516	The	514:516	The	514:516	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	0	8	theme	NiO/activated	77:89	arg1	carbon					91:96	NiO/activated carbon	77:96	NiO/activated carbon	77:96	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	6	9	theme	catalyst	867:874	arg1	dose					876:879	the catalyst dose	863:879	the catalyst dose	863:879	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	5	10	theme	Ni	654:655	arg1	content					665:671	a Ni element content	652:671	a Ni element content of 4.65 wt%	652:683	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	7	11	theme	conversion	1181:1190	arg1	%					1169:1169	99.67 %	1163:1169	99.67 % of CR dye conversion	1163:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	11	theme	conversion	1181:1190	arg1	conversion					1181:1190	CR dye conversion	1174:1190	CR dye conversion	1174:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	2	12	theme	AC-NiO	358:363	arg1	beads					379:383	@AC-NiO nanocomposite beads	357:383	@AC-NiO nanocomposite beads	357:383	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	4	13	theme	XRD	592:594	arg1	techniques					604:613	the XRD and EDS techniques	588:613	techniques	604:613	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	7	14	theme	80 ppm	1140:1145	arg1	dose					1098:1101	catalyst dose	1089:1101	catalyst dose of 11 mg	1089:1110	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	14	theme	80 ppm	1140:1145	arg1	concentration					1064:1076	NaBH4 concentration	1058:1076	NaBH4 concentration of 0.05 M	1058:1086	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	14	theme	80 ppm	1140:1145	arg1	concentration					1123:1135	CR dye concentration	1116:1135	CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion	1116:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	15	theme	NaBH4	1058:1062	arg1	concentration					1064:1076	NaBH4 concentration	1058:1076	NaBH4 concentration of 0.05 M	1058:1086	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	6	16	theme	catalytic	787:795	arg1	reduction					797:805	the catalytic reduction	783:805	the catalytic reduction of the CR dye	783:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	16	theme	catalytic	787:795	arg1	function					826:833	a function	824:833	a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM	824:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	1	17	theme	activated	188:196	arg1	AC-NiO					206:211	AC-NiO	206:211	AC-NiO	206:211	Nickel oxide nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation.					
36764345	1	17	theme	activated	188:196	arg1	carbon					198:203	carbon	198:203	activated carbon (AC-NiO)	188:212	Nickel oxide nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation.					
36764345	5	18	theme	ALG	630:632	arg1	beads					641:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	8	19	with	suitable	1295:1302	arg1	correlation					1316:1326	a good correlation	1309:1326	a good correlation between the experiment	1309:1349	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	6	20	theme	concentration	848:860	arg1	reduction					797:805	the catalytic reduction	783:805	the catalytic reduction of the CR dye	783:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	20	theme	concentration	848:860	arg1	function					826:833	a function	824:833	a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM	824:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	5	21	theme	@	633:633	arg1	beads					641:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	8	22	theme	good	1311:1314	arg1	correlation					1316:1326	a good correlation	1309:1326	a good correlation between the experiment	1309:1349	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	2	23	theme	catalytic	389:397	arg1	reduction					399:407	catalytic reduction	389:407	catalytic reduction of Congo red (CR) dye	389:429	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	7	24	theme	catalytic	1011:1019	arg1	conditions					1029:1038	the catalytic optimum conditions	1007:1038	the catalytic optimum conditions	1007:1038	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	4	25	theme	nanoparticles	559:571	arg1	dispersion					541:550	dispersion	541:550	dispersion	541:550	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	4	25	theme	nanoparticles	559:571	arg1	nature					530:535	crystalline nature	518:535	crystalline nature	518:535	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	5	26	theme	AC-NiO	634:639	arg1	beads					641:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads	630:645	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	7	27	theme	optimum	1021:1027	arg1	conditions					1029:1038	the catalytic optimum conditions	1007:1038	the catalytic optimum conditions	1007:1038	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	0	28	theme	azo	21:23	arg1	dye					25:27	toxic azo dye	15:27	toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon	15:96	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	4	29	theme	NiO	555:557	arg1	nanoparticles					559:571	NiO nanoparticles	555:571	NiO nanoparticles	555:571	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	5	30	theme	%	683:683	arg1	content					665:671	a Ni element content	652:671	a Ni element content of 4.65 wt%	652:683	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	8	31	theme	considered	1268:1277	arg1	suitable					1295:1302	suitable	1295:1302	suitable	1295:1302	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	8	31	theme	considered	1268:1277	arg1	model					1279:1283	the considered model	1264:1283	the considered model	1264:1283	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	0	32	theme	toxic	15:19	arg1	dye					25:27	toxic azo dye	15:27	toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon	15:96	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	6	33	theme	NaBH4	842:846	arg1	concentration					848:860	the NaBH4 concentration	838:860	the NaBH4 concentration	838:860	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	2	34	theme	alginate	297:304	arg1	beads					306:310	alginate beads	297:310	alginate beads	297:310	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	8	35	theme	adjusted	1197:1204	arg1	coefficient					1206:1216	The adjusted coefficient	1193:1216	The adjusted coefficient of determination (R2 = 0.9957)	1193:1247	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	7	36	theme	11 mg	1106:1110	arg1	dose					1098:1101	catalyst dose	1089:1101	catalyst dose of 11 mg	1089:1110	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	36	theme	11 mg	1106:1110	arg1	concentration					1064:1076	NaBH4 concentration	1058:1076	NaBH4 concentration of 0.05 M	1058:1086	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	36	theme	11 mg	1106:1110	arg1	concentration					1123:1135	CR dye concentration	1116:1135	CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion	1116:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	0	37	theme	RSM	133:135	arg1	optimization					137:148	RSM optimization	133:148	RSM optimization	133:148	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	3	38	theme	resulting	436:444	arg1	beads					460:464	The resulting nanocomposite beads	432:464	The resulting nanocomposite beads	432:464	The resulting nanocomposite beads were identified by various physical techniques.					
36764345	2	39	theme	red	418:420	arg1	dye					427:429	Congo red (CR) dye	412:429	Congo red (CR) dye	412:429	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	0	40	theme	dye	25:27	arg1	Elimination					0:10	Elimination	0:10	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.	0:149	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	6	41	theme	dye	913:915	arg1	concentration					848:860	the NaBH4 concentration	838:860	the NaBH4 concentration	838:860	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	41	theme	dye	913:915	arg1	dose					876:879	the catalyst dose	863:879	the catalyst dose	863:879	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	41	theme	dye	913:915	arg1	concentration					889:901	the concentration	885:901	the concentration of the CR dye modeled by a BBD-RSM	885:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	5	42	theme	average	693:699	arg1	diameter					714:721	an average NiO particle diameter	690:721	an average NiO particle diameter of 23 nm	690:730	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	8	43	theme	determination	1221:1233	arg1	coefficient					1206:1216	The adjusted coefficient	1193:1216	The adjusted coefficient of determination (R2 = 0.9957)	1193:1247	The adjusted coefficient of determination (R2 = 0.9957) indicates that the considered model was quite suitable with a good correlation between the experiment and predicted.					
36764345	2	44	theme	dye	427:429	arg1	reduction					399:407	catalytic reduction	389:407	catalytic reduction of Congo red (CR) dye	389:429	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	6	45	theme	statistical	737:747	arg1	approach					749:756	The statistical approach	733:756	The statistical approach	733:756	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	3	46	theme	nanocomposite	446:458	arg1	beads					460:464	The resulting nanocomposite beads	432:464	The resulting nanocomposite beads	432:464	The resulting nanocomposite beads were identified by various physical techniques.					
36764345	0	47	theme	calcium	37:43	arg1	beads					54:58	a calcium alginate beads	35:58	a calcium alginate beads impregnated with NiO/activated carbon	35:96	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	6	48	theme	CR	910:911	arg1	dye					913:915	the CR dye	906:915	the CR dye modeled by a BBD-RSM	906:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	5	49	theme	element	657:663	arg1	content					665:671	a Ni element content	652:671	a Ni element content of 4.65 wt%	652:683	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	7	50	theme	CR	1174:1175	arg1	conversion					1181:1190	CR dye conversion	1174:1190	CR dye conversion	1174:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	1	51	dep	nanoparticles	164:176	arg1	supported					178:186	supported	178:186	nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation	164:252	Nickel oxide nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation.					
36764345	3	52	theme	various	485:491	arg1	techniques					502:511	various physical techniques	485:511	various physical techniques	485:511	The resulting nanocomposite beads were identified by various physical techniques.					
36764345	6	53	theme	dose	876:879	arg1	reduction					797:805	the catalytic reduction	783:805	the catalytic reduction of the CR dye	783:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	53	theme	dose	876:879	arg1	function					826:833	a function	824:833	a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM	824:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	7	54	theme	statistical	956:966	arg1	modeling					968:975	the statistical modeling	952:975	the statistical modeling	952:975	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	3	55	theme	physical	493:500	arg1	techniques					502:511	various physical techniques	485:511	various physical techniques	485:511	The resulting nanocomposite beads were identified by various physical techniques.					
36764345	7	56	theme	CR	1116:1117	arg1	concentration					1123:1135	CR dye concentration	1116:1135	CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion	1116:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	57	theme	optimization	985:996	arg1	process					998:1004	the optimization process	981:1004	the optimization process	981:1004	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	2	58	theme	AC-NiO	261:266	arg1	composite					268:276	AC-NiO composite	261:276	AC-NiO composite	261:276	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	2	59	theme	network	336:342	arg1	structure					344:352	3-dimensional network structure	322:352	3-dimensional network structure	322:352	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	5	60	theme	4.65 wt	676:682	arg1	%					683:683	4.65 wt%	676:683	4.65 wt%	676:683	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	6	61	theme	dye	817:819	arg1	reduction					797:805	the catalytic reduction	783:805	the catalytic reduction of the CR dye	783:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	61	theme	dye	817:819	arg1	function					826:833	a function	824:833	a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM	824:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	2	62	theme	3-dimensional	322:334	arg1	structure					344:352	3-dimensional network structure	322:352	3-dimensional network structure	322:352	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	4	63	theme	EDS	600:602	arg1	techniques					604:613	the XRD and EDS techniques	588:613	techniques	604:613	The crystalline nature and dispersion of NiO nanoparticles was defined by the XRD and EDS techniques, respectively.					
36764345	5	64	theme	23 nm	726:730	arg1	diameter					714:721	an average NiO particle diameter	690:721	an average NiO particle diameter of 23 nm	690:730	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
36764345	6	65	theme	CR	814:815	arg1	dye					817:819	the CR dye	810:819	the CR dye	810:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	1	66	theme	thermal	235:241	arg1	activation					243:252	thermal activation	235:252	thermal activation	235:252	Nickel oxide nanoparticles supported activated carbon (AC-NiO) was fabricated using thermal activation.					
36764345	0	67	theme	alginate	45:52	arg1	beads					54:58	a calcium alginate beads	35:58	a calcium alginate beads impregnated with NiO/activated carbon	35:96	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	6	68	theme	concentration	889:901	arg1	reduction					797:805	the catalytic reduction	783:805	the catalytic reduction of the CR dye	783:819	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	6	68	theme	concentration	889:901	arg1	function					826:833	a function	824:833	a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM	824:936	The statistical approach mathematically describes the catalytic reduction of the CR dye as a function of the NaBH4 concentration, the catalyst dose and the concentration of the CR dye modeled by a BBD-RSM.					
36764345	0	69	dep	Elimination	0:10	arg1	characterization					112:127	characterization	112:127	characterization	112:127	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	0	69	dep	Elimination	0:10	arg1	optimization					137:148	RSM optimization	133:148	RSM optimization	133:148	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	0	69	dep	Elimination	0:10	arg1	Preparation					99:109	Preparation	99:109	Preparation	99:109	Elimination of toxic azo dye using a calcium alginate beads impregnated with NiO/activated carbon: Preparation, characterization and RSM optimization.					
36764345	7	70	theme	0.05 M	1081:1086	arg1	dose					1098:1101	catalyst dose	1089:1101	catalyst dose of 11 mg	1089:1110	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	70	theme	0.05 M	1081:1086	arg1	concentration					1064:1076	NaBH4 concentration	1058:1076	NaBH4 concentration of 0.05 M	1058:1086	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	7	70	theme	0.05 M	1081:1086	arg1	concentration					1123:1135	CR dye concentration	1116:1135	CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion	1116:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	2	71	theme	nanocomposite	365:377	arg1	beads					379:383	@AC-NiO nanocomposite beads	357:383	@AC-NiO nanocomposite beads	357:383	Then, AC-NiO composite was immobilized on alginate beads to obtain 3-dimensional network structure ALG@AC-NiO nanocomposite beads for catalytic reduction of Congo red (CR) dye.					
36764345	7	72	theme	dye	1177:1179	arg1	conversion					1181:1190	CR dye conversion	1174:1190	CR dye conversion	1174:1190	According to the statistical modeling and the optimization process, the catalytic optimum conditions were obtained for NaBH4 concentration of 0.05 M, catalyst dose of 11 mg and CR dye concentration of 80 ppm who permit meet 99.67 % of CR dye conversion.					
36764345	5	73	theme	particle	705:712	arg1	diameter					714:721	an average NiO particle diameter	690:721	an average NiO particle diameter of 23 nm	690:730	ALG@AC-NiO beads have a Ni element content of 4.65 wt% with an average NiO particle diameter of 23 nm.					
35609602	6	0	theme	mechanical	877:886	arg1	properties					888:897	The mechanical properties	873:897	The mechanical properties of composite scaffolds	873:920	The mechanical properties of composite scaffolds were investigated under compression tests experimentally.					
35609602	10	1	from	response	1425:1432	arg1	terms					1460:1464	terms	1460:1464	terms of cell viability, cell proliferation, and cell attachment	1460:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	8	2	theme	scaffolds	1154:1162	arg1	behavior					1134:1141	the mechanical behavior	1119:1141	the mechanical behavior of printed scaffolds	1119:1162	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	11	3	theme	composite	1658:1666	arg1	scaffolds					1668:1676	the composite scaffolds	1654:1676	the composite scaffolds	1654:1676	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	1	4	theme	3D-printed	233:242	arg1	surfaces					290:297	3D-printed polylactic acid-based triply periodic minimal surfaces	233:297	3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs)	233:305	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	4	theme	3D-printed	233:242	arg1	TPMSs					300:304	TPMSs	300:304	TPMSs	300:304	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	8	5	theme	equivalent	1236:1245	arg1	volume					1247:1252	equivalent volume	1236:1252	equivalent volume	1236:1252	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	5	6	theme	real	835:838	arg1	geometries					840:849	the real geometries	831:849	the real geometries of printed scaffolds	831:870	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	8	7	theme	curves	1194:1199	arg1	terms					1167:1171	terms	1167:1171	terms of the strain-stress curves on	1167:1202	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	6	8	theme	compression	946:956	arg1	tests					958:962	compression tests	946:962	compression tests	946:962	The mechanical properties of composite scaffolds were investigated under compression tests experimentally.					
35609602	2	9	theme	regeneration	506:517	arg1	applications					519:530	bone regeneration applications	501:530	bone regeneration applications	501:530	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	13	10	from	scaffolds	2008:2016	arg1	culture					2034:2040	dynamic cell culture	2021:2040	dynamic cell culture	2021:2040	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	7	11	theme	function	1070:1077	arg1	parameters					1079:1088	different implicit function parameters	1051:1088	different implicit function parameters	1051:1088	It was shown that different mechanical behaviors could be obtained for different implicit function parameters.					
35609602	5	12	theme	3D-printed	794:803	arg1	scaffolds					810:818	3D-printed TPMS scaffolds	794:818	3D-printed TPMS scaffolds	794:818	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	8	13	theme	element-based	1265:1277	arg1	volume					1279:1284	finite element-based volume	1258:1284	finite element-based volume	1258:1284	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	7	14	theme	different	1051:1059	arg1	parameters					1079:1088	different implicit function parameters	1051:1088	different implicit function parameters	1051:1088	It was shown that different mechanical behaviors could be obtained for different implicit function parameters.					
35609602	3	15	theme	implicit	552:559	arg1	function					561:568	an implicit function	549:568	an implicit function	549:568	In this regard, an implicit function was used to generate some gyroid TPMS scaffolds.					
35609602	7	16	theme	different	998:1006	arg1	behaviors					1019:1027	different mechanical behaviors	998:1027	different mechanical behaviors	998:1027	It was shown that different mechanical behaviors could be obtained for different implicit function parameters.					
35609602	5	17	theme	scaffolds	810:818	arg1	microstructure					776:789	the microstructure	772:789	the microstructure of 3D-printed TPMS scaffolds	772:818	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	6	18	theme	scaffolds	912:920	arg1	properties					888:897	The mechanical properties	873:897	The mechanical properties of composite scaffolds	873:920	The mechanical properties of composite scaffolds were investigated under compression tests experimentally.					
35609602	1	19	theme	acid-based	255:264	arg1	surfaces					290:297	3D-printed polylactic acid-based triply periodic minimal surfaces	233:297	3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs)	233:305	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	19	theme	acid-based	255:264	arg1	TPMSs					300:304	TPMSs	300:304	TPMSs	300:304	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	13	20	theme	better	2049:2054	arg1	response					2067:2074	a better biological response	2047:2074	a better biological response	2047:2074	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	11	21	theme	cell	1735:1738	arg1	proliferation					1740:1752	cell proliferation	1735:1752	cell proliferation	1735:1752	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	14	22	from	adhesion	2173:2180	arg1	scaffolds					2199:2207	the composite scaffolds	2185:2207	the composite scaffolds	2185:2207	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	4	23	theme	deposition	634:643	arg1	process					654:660	the fused deposition modeling process	624:660	the fused deposition modeling process	624:660	Then the fused deposition modeling process was employed to print the scaffolds.					
35609602	0	24	theme	novel	49:53	arg1	scaffolds					60:68	novel bone scaffolds	49:68	novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	49:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	13	25	theme	cell	2029:2032	arg1	culture					2034:2040	dynamic cell culture	2021:2040	dynamic cell culture	2021:2040	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	12	26	theme	static	1967:1972	arg1	cultures					1974:1981	both dynamic and static cultures	1950:1981	both dynamic and static cultures	1950:1981	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	2	27	theme	suitable	460:467	arg1	size					474:477	a suitable pore size	458:477	a suitable pore size	458:477	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	2	28	used	used	493:496	arg2	size					474:477	a suitable pore size	458:477	a suitable pore size	458:477	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	0	29	theme	scaffolds	60:68	arg1	study					40:44	vitrostatic and dynamic cell culture study	3:44	vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	3:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	1	30	theme	cell-laden	311:320	arg1	hydrogel					331:338	cell-laden alginate hydrogel	311:338	cell-laden alginate hydrogel	311:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	5	31	theme	scaffolds	862:870	arg1	geometries					840:849	the real geometries	831:849	the real geometries of printed scaffolds	831:870	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	11	32	theme	mechanical	1690:1699	arg1	loading					1701:1707	mechanical loading	1690:1707	mechanical loading	1690:1707	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	10	33	theme	composite	1437:1445	arg1	scaffolds					1447:1455	composite scaffolds	1437:1455	composite scaffolds	1437:1455	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	9	34	theme	strain-stress	1298:1310	arg1	curves					1312:1317	strain-stress curves	1298:1317	strain-stress curves	1298:1317	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	10	35	theme	viability	1474:1482	arg1	terms					1460:1464	terms	1460:1464	terms of cell viability, cell proliferation, and cell attachment	1460:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	2	36	theme	low	374:376	arg1	properties					389:398	the low mechanical properties	370:398	the low mechanical properties of alginate hydrogel	370:419	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	0	37	theme	culture	32:38	arg1	study					40:44	vitrostatic and dynamic cell culture study	3:44	vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	3:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	14	38	theme	excellent	2223:2231	arg1	attachment					2233:2242	excellent attachment	2223:2242	excellent attachment between the scaffolds and cells	2223:2274	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	1	39	theme	polylactic	244:253	arg1	surfaces					290:297	3D-printed polylactic acid-based triply periodic minimal surfaces	233:297	3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs)	233:305	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	39	theme	polylactic	244:253	arg1	TPMSs					300:304	TPMSs	300:304	TPMSs	300:304	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	2	40	theme	alginate	403:410	arg1	hydrogel					412:419	alginate hydrogel	403:419	alginate hydrogel	403:419	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	9	41	theme	based	1350:1354	arg1	approach					1356:1363	the finite-element based approach	1331:1363	the finite-element based approach	1331:1363	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	10	42	theme	cell	1485:1488	arg1	proliferation					1490:1502	cell proliferation	1485:1502	cell proliferation	1485:1502	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	3	43	theme	TPMS	603:606	arg1	scaffolds					608:616	some gyroid TPMS scaffolds	591:616	some gyroid TPMS scaffolds	591:616	In this regard, an implicit function was used to generate some gyroid TPMS scaffolds.					
35609602	0	44	theme	cell	27:30	arg1	study					40:44	vitrostatic and dynamic cell culture study	3:44	vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	3:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	1	45	theme	minimal	282:288	arg1	surfaces					290:297	3D-printed polylactic acid-based triply periodic minimal surfaces	233:297	3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs)	233:305	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	45	theme	minimal	282:288	arg1	TPMSs					300:304	TPMSs	300:304	TPMSs	300:304	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	12	46	theme	scaffolds	1800:1808	arg1	results					1769:1775	the results	1765:1775	the results of the novel composite scaffolds	1765:1808	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	14	47	theme	electron	2122:2129	arg1	microscopy					2131:2140	scanning electron microscopy	2113:2140	scanning electron microscopy	2113:2140	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	9	48	theme	higher	1376:1381	arg1	level					1383:1387	a higher level	1374:1387	a higher level of stress	1374:1397	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	12	49	from	proliferation	1933:1945	arg1	cultures					1974:1981	both dynamic and static cultures	1950:1981	both dynamic and static cultures	1950:1981	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	10	50	theme	cell	1509:1512	arg1	attachment					1514:1523	cell attachment	1509:1523	cell attachment	1509:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	11	51	theme	culture	1572:1578	arg1	system					1580:1585	a dynamic cell culture system	1557:1585	a dynamic cell culture system	1557:1585	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	1	52	theme	composite	186:194	arg1	scaffold					196:203	a novel composite scaffold	178:203	a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel	178:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	14	53	theme	composite	2189:2197	arg1	scaffolds					2199:2207	the composite scaffolds	2185:2207	the composite scaffolds	2185:2207	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	2	54	theme	novel	346:350	arg1	scaffold					352:359	This novel scaffold	341:359	This novel scaffold	341:359	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	12	55	theme	novel	1784:1788	arg1	scaffolds					1800:1808	the novel composite scaffolds	1780:1808	the novel composite scaffolds	1780:1808	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	14	56	theme	cell	2168:2171	arg1	adhesion					2173:2180	the cell adhesion	2164:2180	the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells	2164:2274	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	11	57	theme	dynamic	1559:1565	arg1	system					1580:1585	a dynamic cell culture system	1557:1585	a dynamic cell culture system	1557:1585	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	8	58	theme	printed	1146:1152	arg1	scaffolds					1154:1162	printed scaffolds	1146:1162	printed scaffolds	1146:1162	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	1	59	theme	paper	144:148	arg1	aim					132:134	The aim	128:134	The aim of this paper	128:148	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	59	theme	paper	144:148	arg1	design					157:162	design	157:162	design	157:162	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	5	60	theme	computed	719:726	arg1	tomography					728:737	micro computed tomography	713:737	the micro computed tomography technique	709:747	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	10	61	theme	biological	1414:1423	arg1	response					1425:1432	the biological response	1410:1432	the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment	1410:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	7	62	theme	implicit	1061:1068	arg1	parameters					1079:1088	different implicit function parameters	1051:1088	different implicit function parameters	1051:1088	It was shown that different mechanical behaviors could be obtained for different implicit function parameters.					
35609602	8	63	theme	strain-stress	1180:1192	arg1	curves					1194:1199	the strain-stress curves	1176:1199	the strain-stress curves on	1176:1202	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	2	64	theme	bone	501:504	arg1	applications					519:530	bone regeneration applications	501:530	bone regeneration applications	501:530	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	4	65	theme	modeling	645:652	arg1	process					654:660	the fused deposition modeling process	624:660	the fused deposition modeling process	624:660	Then the fused deposition modeling process was employed to print the scaffolds.					
35609602	14	66	theme	scanning	2113:2120	arg1	microscopy					2131:2140	scanning electron microscopy	2113:2140	scanning electron microscopy	2113:2140	In addition, scanning electron microscopy was employed to study the cell adhesion on the composite scaffolds, which showed excellent attachment between the scaffolds and cells.					
35609602	13	67	theme	static	2084:2089	arg1	culture					2091:2097	static culture	2084:2097	static culture	2084:2097	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	5	68	theme	TPMS	805:808	arg1	scaffolds					810:818	3D-printed TPMS scaffolds	794:818	3D-printed TPMS scaffolds	794:818	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	8	69	theme	finite	1258:1263	arg1	volume					1279:1284	finite element-based volume	1258:1284	finite element-based volume	1258:1284	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	7	70	theme	mechanical	1008:1017	arg1	behaviors					1019:1027	different mechanical behaviors	998:1027	different mechanical behaviors	998:1027	It was shown that different mechanical behaviors could be obtained for different implicit function parameters.					
35609602	12	71	theme	cell	1928:1931	arg1	proliferation					1933:1945	cell proliferation	1928:1945	cell proliferation	1928:1945	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	6	72	theme	composite	902:910	arg1	scaffolds					912:920	composite scaffolds	902:920	composite scaffolds	902:920	The mechanical properties of composite scaffolds were investigated under compression tests experimentally.					
35609602	0	73	theme	alginate	109:116	arg1	hydrogel					118:125	cell-laden alginate hydrogel	98:125	cell-laden alginate hydrogel	98:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	13	74	theme	biological	2056:2065	arg1	response					2067:2074	a better biological response	2047:2074	a better biological response	2047:2074	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	13	75	contain	have	2042:2045	arg1	scaffolds					2008:2016	scaffolds	2008:2016	scaffolds in dynamic cell culture	2008:2040	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	13	75	contain	have	2042:2045	arg2	response					2067:2074	a better biological response	2047:2074	a better biological response	2047:2074	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	0	76	theme	bone	55:58	arg1	scaffolds					60:68	novel bone scaffolds	49:68	novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	49:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	2	77	theme	pore	469:472	arg1	size					474:477	a suitable pore size	458:477	a suitable pore size	458:477	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	12	78	theme	dynamic	1955:1961	arg1	cultures					1974:1981	both dynamic and static cultures	1950:1981	both dynamic and static cultures	1950:1981	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	4	79	theme	fused	628:632	arg1	process					654:660	the fused deposition modeling process	624:660	the fused deposition modeling process	624:660	Then the fused deposition modeling process was employed to print the scaffolds.					
35609602	5	80	theme	micro	713:717	arg1	tomography					728:737	micro computed tomography	713:737	the micro computed tomography technique	709:747	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	2	81	with	scaffold	444:451	arg1	size					474:477	a suitable pore size	458:477	a suitable pore size	458:477	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	5	82	theme	printed	854:860	arg1	scaffolds					862:870	printed scaffolds	854:870	printed scaffolds	854:870	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	1	83	theme	hydrogel	331:338	arg1	combination					218:228	the combination	214:228	the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel	214:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	0	84	theme	cell-laden	98:107	arg1	hydrogel					118:125	cell-laden alginate hydrogel	98:125	cell-laden alginate hydrogel	98:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	10	85	theme	scaffolds	1447:1455	arg1	response					1425:1432	the biological response	1410:1432	the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment	1410:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	3	86	used	used	574:577	arg2	function					561:568	an implicit function	549:568	an implicit function	549:568	In this regard, an implicit function was used to generate some gyroid TPMS scaffolds.					
35609602	0	87	theme	3D-printed	79:88	arg1	PLA					90:92	3D-printed PLA	79:92	3D-printed PLA	79:92	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	1	88	theme	alginate	322:329	arg1	hydrogel					331:338	cell-laden alginate hydrogel	311:338	cell-laden alginate hydrogel	311:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	9	89	theme	curves	1312:1317	arg1	Results					1287:1293	Results	1287:1293	Results of strain-stress curves	1287:1317	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	10	90	theme	cell	1469:1472	arg1	viability					1474:1482	cell viability	1469:1482	cell viability	1469:1482	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	0	91	theme	vitrostatic	3:13	arg1	study					40:44	vitrostatic and dynamic cell culture study	3:44	vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	3:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	13	92	theme	dynamic	2021:2027	arg1	culture					2034:2040	dynamic cell culture	2021:2040	dynamic cell culture	2021:2040	Also, it was shown that scaffolds in dynamic cell culture have a better biological response than in static culture.					
35609602	12	93	theme	composite	1877:1885	arg1	scaffold					1887:1894	the composite scaffold	1873:1894	the composite scaffold	1873:1894	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	12	94	from	viability	1914:1922	arg1	cultures					1974:1981	both dynamic and static cultures	1950:1981	both dynamic and static cultures	1950:1981	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	0	95	theme	dynamic	19:25	arg1	study					40:44	vitrostatic and dynamic cell culture study	3:44	vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel	3:125	In vitrostatic and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel.					
35609602	9	96	theme	finite-element	1335:1348	arg1	approach					1356:1363	the finite-element based approach	1331:1363	the finite-element based approach	1331:1363	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	2	97	theme	hydrogel	412:419	arg1	properties					389:398	the low mechanical properties	370:398	the low mechanical properties of alginate hydrogel	370:419	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	10	98	theme	proliferation	1490:1502	arg1	terms					1460:1464	terms	1460:1464	terms of cell viability, cell proliferation, and cell attachment	1460:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	3	99	theme	gyroid	596:601	arg1	scaffolds					608:616	some gyroid TPMS scaffolds	591:616	some gyroid TPMS scaffolds	591:616	In this regard, an implicit function was used to generate some gyroid TPMS scaffolds.					
35609602	5	100	theme	tomography	728:737	arg1	technique					739:747	the micro computed tomography technique	709:747	the micro computed tomography technique	709:747	Moreover, the micro computed tomography technique was employed to assess the microstructure of 3D-printed TPMS scaffolds and obtain the real geometries of printed scaffolds.					
35609602	1	101	theme	periodic	273:280	arg1	surfaces					290:297	3D-printed polylactic acid-based triply periodic minimal surfaces	233:297	3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs)	233:305	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	1	101	theme	periodic	273:280	arg1	TPMSs					300:304	TPMSs	300:304	TPMSs	300:304	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	2	102	theme	mechanical	378:387	arg1	properties					389:398	the low mechanical properties	370:398	the low mechanical properties of alginate hydrogel	370:419	This novel scaffold improves the low mechanical properties of alginate hydrogel and can also provide a scaffold with a suitable pore size, which can be used in bone regeneration applications.					
35609602	1	103	theme	surfaces	290:297	arg1	combination					218:228	the combination	214:228	the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel	214:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	12	104	theme	composite	1790:1798	arg1	scaffolds					1800:1808	the novel composite scaffolds	1780:1808	the novel composite scaffolds	1780:1808	Moreover, the results of the novel composite scaffolds were compared to those without alginate, and it was shown that the composite scaffold could create more viability and cell proliferation in both dynamic and static cultures.					
35609602	10	105	theme	attachment	1514:1523	arg1	terms					1460:1464	terms	1460:1464	terms of cell viability, cell proliferation, and cell attachment	1460:1523	Moreover, the biological response of composite scaffolds in terms of cell viability, cell proliferation, and cell attachment was investigated.					
35609602	11	106	theme	cell	1567:1570	arg1	system					1580:1585	a dynamic cell culture system	1557:1585	a dynamic cell culture system	1557:1585	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
35609602	9	107	theme	stress	1392:1397	arg1	level					1383:1387	a higher level	1374:1387	a higher level of stress	1374:1397	Results of strain-stress curves showed that the finite-element based approach predicts a higher level of stress.					
35609602	8	108	theme	mechanical	1123:1132	arg1	behavior					1134:1141	the mechanical behavior	1119:1141	the mechanical behavior of printed scaffolds	1119:1162	In this research, to assess the mechanical behavior of printed scaffolds in terms of the strain-stress curves on, two approaches were presented: equivalent volume and finite element-based volume.					
35609602	1	109	theme	novel	180:184	arg1	scaffold					196:203	a novel composite scaffold	178:203	a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel	178:338	The aim of this paper was to design and fabricate a novel composite scaffold based on the combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) and cell-laden alginate hydrogel.					
35609602	11	110	theme	mass	1631:1634	arg1	transport					1636:1644	mass transport	1631:1644	mass transport	1631:1644	In this vein, a dynamic cell culture system was designed and fabricated, which improves mass transport through the composite scaffolds and applies mechanical loading to the cells, which helps cell proliferation.					
36144758	5	0	theme	CAF	717:719	arg1	shell					721:725	the CAF shell	713:725	the CAF shell	713:725	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	8	1	theme	different	1058:1066	arg1	conditions					1068:1077	different conditions	1058:1077	different conditions	1058:1077	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	8	2	theme	composite	987:995	arg1	carrier					997:1003	the composite carrier	983:1003	the composite carrier	983:1003	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	8	2	theme	composite	987:995	arg1	stable					1016:1021	stable	1016:1021	stable	1016:1021	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	1	3	theme	sensory	176:182	arg1	quality					184:190	the sensory quality	172:190	the sensory quality	172:190	Fragrances have been widely used in many customer products to improve the sensory quality and cover flavor defects.					
36144758	5	4	theme	shell	721:725	arg1	effect					659:664	The encapsulation effect	641:664	The encapsulation effect of MIL-101 (Cr)	641:680	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	5	4	theme	shell	721:725	arg1	function					701:708	the protective function	686:708	the protective function of the CAF shell	686:725	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	4	5	theme	fragrance	510:518	arg1	carrier					520:526	a novel composite fragrance carrier	492:526	a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell	492:624	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	2	6	theme	carrier	355:361	arg1	use					333:335	the use	329:335	the use of an appropriate carrier for fragrance	329:375	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	8	7	with	stable	1016:1021	arg1	leaching					1043:1050	neglectable Cr leaching	1028:1050	neglectable Cr leaching	1028:1050	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	4	8	theme	fragrance	553:561	arg1	host					563:566	the fragrance host	549:566	the fragrance host	549:566	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	4	9	theme	composite	500:508	arg1	carrier					520:526	a novel composite fragrance carrier	492:526	a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell	492:624	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	9	10	theme	work	1100:1103	arg1	results					1084:1090	The results	1080:1090	The results of this work	1080:1103	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	4	11	theme	cellulose	572:580	arg1	fiber					590:594	cellulose acetate fiber	572:594	cellulose acetate fiber (CAF)	572:600	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	4	11	theme	cellulose	572:580	arg1	CAF					597:599	CAF	597:599	CAF	597:599	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	9	12	theme	fragrance	1217:1225	arg1	release					1206:1212	the thermally triggered release	1182:1212	the thermally triggered release of fragrance	1182:1225	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	7	13	theme	Encapsulated	864:875	arg1	LM					877:878	Encapsulated LM	864:878	Encapsulated LM	864:878	Encapsulated LM could also be effectively released upon heating due to the thermal responsiveness of CAF.					
36144758	5	14	theme	protective	690:699	arg1	function					701:708	the protective function	686:708	the protective function of the CAF shell	686:725	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	2	15	theme	appropriate	343:353	arg1	carrier					355:361	an appropriate carrier	340:361	an appropriate carrier for fragrance	340:375	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	2	16	theme	fragrance	294:302	arg1	release					304:310	controlled fragrance release	283:310	controlled fragrance release	283:310	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	3	17	theme	stable	426:431	arg1	storage					433:439	the stable storage	422:439	the stable storage	422:439	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
36144758	5	18	theme	storage	754:760	arg1	stability					762:770	the storage stability	750:770	the storage stability of L-menthol (LM)	750:788	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	2	19	theme	controlled	283:292	arg1	release					304:310	controlled fragrance release	283:310	controlled fragrance release	283:310	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	3	20	theme	controlled	445:454	arg1	release					456:462	controlled release	445:462	controlled release of fragrance	445:475	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
36144758	0	21	theme	Thermal	11:17	arg1	Release					19:25	Thermal Release	11:25	Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	11:99	Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework.					
36144758	6	22	theme	LM	806:807	arg1	LM					806:807	LM	806:807	LM	806:807	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	6	22	theme	LM	806:807	arg1	%					801:801	Only 5 wt %	791:801	Only 5 wt % of LM	791:807	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	7	23	theme	CAF	965:967	arg1	responsiveness					947:960	the thermal responsiveness	935:960	the thermal responsiveness of CAF	935:967	Encapsulated LM could also be effectively released upon heating due to the thermal responsiveness of CAF.					
36144758	1	24	theme	flavor	202:207	arg1	defects					209:215	flavor defects	202:215	flavor defects	202:215	Fragrances have been widely used in many customer products to improve the sensory quality and cover flavor defects.					
36144758	9	25	theme	developed	1121:1129	arg1	carrier					1170:1176	a promising carrier	1158:1176	a promising carrier for the thermally triggered release of fragrance	1158:1225	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	9	25	theme	developed	1121:1129	arg1	carrier					1141:1147	the developed composite carrier	1117:1147	the developed composite carrier	1117:1147	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	5	26	theme	L-menthol	775:783	arg1	stability					762:770	the storage stability	750:770	the storage stability of L-menthol (LM)	750:788	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	5	27	theme	MIL-101	669:675	arg1	effect					659:664	The encapsulation effect	641:664	The encapsulation effect of MIL-101 (Cr)	641:680	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	5	27	theme	MIL-101	669:675	arg1	function					701:708	the protective function	686:708	the protective function of the CAF shell	686:725	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	9	28	theme	composite	1131:1139	arg1	carrier					1170:1176	a promising carrier	1158:1176	a promising carrier for the thermally triggered release of fragrance	1158:1225	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	9	28	theme	composite	1131:1139	arg1	carrier					1141:1147	the developed composite carrier	1117:1147	the developed composite carrier	1117:1147	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	3	29	theme	fragrance	467:475	arg1	storage					433:439	the stable storage	422:439	the stable storage	422:439	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
36144758	3	29	theme	fragrance	467:475	arg1	release					456:462	controlled release	445:462	controlled release of fragrance	445:475	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
36144758	3	30	theme	ideal	381:385	arg1	carrier					397:403	An ideal fragrance carrier	378:403	An ideal fragrance carrier	378:403	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
36144758	4	31	with	carrier	520:526	arg1	MIL-101					533:539	MIL-101	533:539	MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF)	533:600	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	4	31	with	carrier	520:526	arg1	Cr					542:543	Cr	542:543	Cr	542:543	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	1	32	theme	customer	143:150	arg1	products					152:159	many customer products	138:159	many customer products	138:159	Fragrances have been widely used in many customer products to improve the sensory quality and cover flavor defects.					
36144758	4	33	theme	protective	609:618	arg1	shell					620:624	the protective shell	605:624	the protective shell	605:624	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	0	34	theme	L-Menthol	30:38	arg1	Release					19:25	Thermal Release	11:25	Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	11:99	Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework.					
36144758	6	35	theme	wt	798:799	arg1	LM					806:807	LM	806:807	LM	806:807	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	6	35	theme	wt	798:799	arg1	%					801:801	Only 5 wt %	791:801	Only 5 wt % of LM	791:807	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	0	36	theme	Metal-Organic	77:89	arg1	Framework					91:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework.					
36144758	8	37	from	addition	973:980	arg1	carrier					997:1003	the composite carrier	983:1003	the composite carrier	983:1003	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	8	37	from	addition	973:980	arg1	stable					1016:1021	stable	1016:1021	stable	1016:1021	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	2	38	theme	successful	233:242	arg1	application					244:254	the successful application	229:254	the successful application of fragrance	229:267	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	0	39	with	Release	19:25	arg1	Framework					91:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework.					
36144758	1	40	theme	many	138:141	arg1	products					152:159	many customer products	138:159	many customer products	138:159	Fragrances have been widely used in many customer products to improve the sensory quality and cover flavor defects.					
36144758	0	41	theme	Cellulose-Acetate-Fiber-Shelled	45:75	arg1	Framework					91:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework	45:99	Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework.					
36144758	6	42	theme	room	846:849	arg1	temperature					851:861	room temperature	846:861	room temperature	846:861	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	5	43	theme	encapsulation	645:657	arg1	effect					659:664	The encapsulation effect	641:664	The encapsulation effect of MIL-101 (Cr)	641:680	The encapsulation effect of MIL-101 (Cr) and the protective function of the CAF shell significantly improved the storage stability of L-menthol (LM).					
36144758	9	44	theme	promising	1160:1168	arg1	carrier					1170:1176	a promising carrier	1158:1176	a promising carrier for the thermally triggered release of fragrance	1158:1225	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	9	44	theme	promising	1160:1168	arg1	carrier					1141:1147	the developed composite carrier	1117:1147	the developed composite carrier	1117:1147	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	9	45	theme	triggered	1196:1204	arg1	release					1206:1212	the thermally triggered release	1182:1212	the thermally triggered release of fragrance	1182:1225	The results of this work showed that the developed composite carrier could be a promising carrier for the thermally triggered release of fragrance.					
36144758	1	46	used	used	130:133	arg2	Fragrances					102:111	Fragrances	102:111	Fragrances	102:111	Fragrances have been widely used in many customer products to improve the sensory quality and cover flavor defects.					
36144758	7	47	theme	thermal	939:945	arg1	responsiveness					947:960	the thermal responsiveness	935:960	the thermal responsiveness of CAF	935:967	Encapsulated LM could also be effectively released upon heating due to the thermal responsiveness of CAF.					
36144758	8	48	from	stable	1016:1021	arg1	addition					973:980	addition	973:980	addition	973:980	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	8	49	theme	neglectable	1028:1038	arg1	leaching					1043:1050	neglectable Cr leaching	1028:1050	neglectable Cr leaching	1028:1050	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	4	50	theme	acetate	582:588	arg1	fiber					590:594	cellulose acetate fiber	572:594	cellulose acetate fiber (CAF)	572:600	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	4	50	theme	acetate	582:588	arg1	CAF					597:599	CAF	597:599	CAF	597:599	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	6	51	theme	storage	835:841	arg1	days					827:830	40 days	824:830	40 days of storage	824:841	Only 5 wt % of LM was lost after 40 days of storage at room temperature.					
36144758	8	52	theme	Cr	1040:1041	arg1	leaching					1043:1050	neglectable Cr leaching	1028:1050	neglectable Cr leaching	1028:1050	In addition, the composite carrier was highly stable with neglectable Cr leaching under different conditions.					
36144758	4	53	theme	novel	494:498	arg1	carrier					520:526	a novel composite fragrance carrier	492:526	a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell	492:624	In this work, a novel composite fragrance carrier with MIL-101 (Cr) as the fragrance host and cellulose acetate fiber (CAF) as the protective shell was developed.					
36144758	2	54	theme	fragrance	259:267	arg1	application					244:254	the successful application	229:254	the successful application of fragrance	229:267	The key to the successful application of fragrance is to realize controlled fragrance release, which relies on the use of an appropriate carrier for fragrance.					
36144758	3	55	theme	fragrance	387:395	arg1	carrier					397:403	An ideal fragrance carrier	378:403	An ideal fragrance carrier	378:403	An ideal fragrance carrier helps to achieve the stable storage and controlled release of fragrance.					
35405607	0	0	theme	oil/water	98:106	arg1	separation					108:117	high-flux and highly-efficient oil/water separation	67:117	high-flux and highly-efficient oil/water separation	67:117	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	2	1	theme	nanofibrous	564:574	arg1	membrane					576:583	the starch nanofibrous membrane	553:583	the starch nanofibrous membrane on a large scale	553:600	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	3	2	theme	hydrated	817:824	arg1	matrix					863:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	1	3	theme	porous	189:194	arg1	architecture					196:207	tunable porous architecture	181:207	tunable porous architecture	181:207	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	4	theme	secondary	284:292	arg1	problem					396:402	a thorny problem	387:402	a thorny problem	387:402	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	4	theme	secondary	284:292	arg1	pollution					301:309	the serious secondary marine pollution	272:309	the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves	272:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	0	5	theme	highly-efficient	81:96	arg1	separation					108:117	high-flux and highly-efficient oil/water separation	67:117	high-flux and highly-efficient oil/water separation	67:117	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	1	6	theme	thorny	389:394	arg1	problem					396:402	a thorny problem	387:402	a thorny problem	387:402	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	6	theme	thorny	389:394	arg1	pollution					301:309	the serious secondary marine pollution	272:309	the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves	272:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	4	7	theme	resulting	974:982	arg1	membrane					984:991	the resulting membrane	970:991	the resulting membrane	970:991	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	1	8	theme	marine	294:299	arg1	problem					396:402	a thorny problem	387:402	a thorny problem	387:402	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	8	theme	marine	294:299	arg1	pollution					301:309	the serious secondary marine pollution	272:309	the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves	272:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	4	9	theme	efficiency	1047:1056	arg1	performance					1011:1021	outstanding performance	999:1021	outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1)	999:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	10	theme	synergistic	791:801	arg1	effect					803:808	the synergistic effect	787:808	the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix	787:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	11	theme	outstanding	999:1009	arg1	performance					1011:1021	outstanding performance	999:1021	outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1)	999:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	12	theme	novel	616:620	arg1	membranes					632:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	13	theme	microfiltration	1160:1174	arg1	membranes					1176:1184	the conventional microfiltration membranes	1143:1184	the conventional microfiltration membranes	1143:1184	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	5	14	theme	long-term	1329:1337	arg1	remediation					1350:1360	long-term wastewater remediation	1329:1360	long-term wastewater remediation	1329:1360	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	3	15	theme	integrated	650:659	arg1	properties					661:670	integrated properties	650:670	integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity	650:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	16	theme	nanonet-skin-layer	826:843	arg1	matrix					863:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	17	theme	composite	622:630	arg1	membranes					632:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	18	theme	excellent	1026:1034	arg1	flux					1092:1095	high percolation flux	1075:1095	high percolation flux (maximum of 15968 L m-2 h-1)	1075:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	18	theme	excellent	1026:1034	arg1	%					1071:1071	up to 99.996%	1059:1071	up to 99.996%	1059:1071	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	18	theme	excellent	1026:1034	arg1	efficiency					1047:1056	excellent separation efficiency	1026:1056	excellent separation efficiency (up to 99.996%)	1026:1072	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	5	19	theme	wastewater	1339:1348	arg1	remediation					1350:1360	long-term wastewater remediation	1329:1360	long-term wastewater remediation	1329:1360	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	2	20	theme	large	590:594	arg1	scale					596:600	a large scale	588:600	a large scale	588:600	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	4	21	theme	thickness	959:967	arg1	virtue					874:879	virtue	874:879	virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness	874:967	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	22	theme	15968 L m-2	1109:1119	arg1	h-1					1121:1123	15968 L m-2 h-1	1109:1123	15968 L m-2 h-1	1109:1123	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	23	theme	ultrathin	949:957	arg1	thickness					959:967	ultrathin thickness	949:967	ultrathin thickness	949:967	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	0	24	theme	Biodegradable	0:12	arg1	membranes					50:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	1	25	theme	oil-water	213:221	arg1	separation					223:232	oil-water separation	213:232	oil-water separation	213:232	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	2	26	theme	bacterial	521:529	arg1	nanonets					541:548	two-dimensional bacterial cellulose nanonets	505:548	two-dimensional bacterial cellulose nanonets	505:548	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	2	27	theme	starch	557:562	arg1	membrane					576:583	the starch nanofibrous membrane	553:583	the starch nanofibrous membrane on a large scale	553:600	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	2	28	with	membrane	439:446	arg1	nanostructure					476:488	biomimetic cobweb-like nanostructure	453:488	biomimetic cobweb-like nanostructure	453:488	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	1	29	with	membranes	127:135	arg1	surface					169:175	fascinating super-wettable surface	142:175	fascinating super-wettable surface	142:175	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	29	with	membranes	127:135	arg1	architecture					196:207	tunable porous architecture	181:207	tunable porous architecture	181:207	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	3	30	theme	matrix	863:868	arg1	effect					803:808	the synergistic effect	787:808	the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix	787:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	1	31	theme	Porous	120:125	arg1	membranes					127:135	Porous membranes	120:135	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation	120:232	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	4	32	theme	porosity	935:942	arg1	virtue					874:879	virtue	874:879	virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness	874:967	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	0	33	theme	biomimetic	15:24	arg1	membranes					50:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	1	34	theme	non-degradable	325:338	arg1	defectiveness					340:352	the non-degradable defectiveness	321:352	the non-degradable defectiveness of membranes themselves	321:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	2	35	theme	two-dimensional	505:519	arg1	nanonets					541:548	two-dimensional bacterial cellulose nanonets	505:548	two-dimensional bacterial cellulose nanonets	505:548	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	2	36	theme	cobweb-like	464:474	arg1	nanostructure					476:488	biomimetic cobweb-like nanostructure	453:488	biomimetic cobweb-like nanostructure	453:488	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	0	37	theme	nanonet-engineered	31:48	arg1	membranes					50:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes	0:58	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	3	38	theme	starch	856:861	arg1	matrix					863:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	39	theme	underwater	742:751	arg1	superoleophobicity					753:770	underwater superoleophobicity	742:770	underwater superoleophobicity	742:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	40	theme	pore	686:689	arg1	size					691:694	sub-micron pore size	675:694	sub-micron pore size	675:694	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	2	41	theme	biomimetic	453:462	arg1	nanostructure					476:488	biomimetic cobweb-like nanostructure	453:488	biomimetic cobweb-like nanostructure	453:488	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	4	42	dep	99.996	1065:1070	arg1	to					1062:1063	to	1062:1063	to	1062:1063	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	43	theme	superhydrophilicity	717:735	arg1	properties					661:670	integrated properties	650:670	integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity	650:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	44	theme	size	691:694	arg1	properties					661:670	integrated properties	650:670	integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity	650:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	5	45	theme	robust	1309:1314	arg1	membrane					1281:1288	the membrane	1277:1288	the membrane	1277:1288	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	5	45	theme	robust	1309:1314	arg1	platform					1316:1323	the robust platform	1305:1323	the robust platform for long-term wastewater remediation	1305:1360	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	4	46	theme	h-1	1121:1123	arg1	maximum					1098:1104	maximum	1098:1104	maximum of 15968 L m-2 h-1	1098:1123	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	1	47	theme	membranes	357:365	arg1	defectiveness					340:352	the non-degradable defectiveness	321:352	the non-degradable defectiveness of membranes themselves	321:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	2	48	from	membrane	576:583	arg1	scale					596:600	a large scale	588:600	a large scale	588:600	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	5	49	theme	anti-oil-fouling	1250:1265	arg1	property					1267:1274	anti-oil-fouling property	1250:1274	anti-oil-fouling property	1250:1274	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	2	50	theme	cellulose	531:539	arg1	nanonets					541:548	two-dimensional bacterial cellulose nanonets	505:548	two-dimensional bacterial cellulose nanonets	505:548	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	4	51	dep	flux	1092:1095	arg1	maximum					1098:1104	maximum	1098:1104	maximum of 15968 L m-2 h-1	1098:1123	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	52	theme	sub-micron	675:684	arg1	size					691:694	sub-micron pore size	675:694	sub-micron pore size	675:694	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	1	53	theme	fascinating	142:152	arg1	surface					169:175	fascinating super-wettable surface	142:175	fascinating super-wettable surface	142:175	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	4	54	theme	pores	918:922	arg1	virtue					874:879	virtue	874:879	virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness	874:967	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	55	theme	separation	1036:1045	arg1	flux					1092:1095	high percolation flux	1075:1095	high percolation flux (maximum of 15968 L m-2 h-1)	1075:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	55	theme	separation	1036:1045	arg1	%					1071:1071	up to 99.996%	1059:1071	up to 99.996%	1059:1071	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	55	theme	separation	1036:1045	arg1	efficiency					1047:1056	excellent separation efficiency	1026:1056	excellent separation efficiency (up to 99.996%)	1026:1072	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	56	theme	sub-micron	907:916	arg1	pores					918:922	the narrow-distributed sub-micron pores	884:922	the narrow-distributed sub-micron pores	884:922	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	57	theme	porosity	707:714	arg1	properties					661:670	integrated properties	650:670	integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity	650:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	58	theme	ultrahigh	925:933	arg1	porosity					935:942	ultrahigh porosity	925:942	ultrahigh porosity	925:942	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	1	59	theme	super-wettable	154:167	arg1	surface					169:175	fascinating super-wettable surface	142:175	fascinating super-wettable surface	142:175	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	3	60	theme	obtained	607:614	arg1	membranes					632:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes	603:640	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	3	61	theme	superoleophobicity	753:770	arg1	properties					661:670	integrated properties	650:670	integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity	650:770	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	62	theme	narrow-distributed	888:905	arg1	pores					918:922	the narrow-distributed sub-micron pores	884:922	the narrow-distributed sub-micron pores	884:922	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	3	63	theme	porous	849:854	arg1	matrix					863:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	the hydrated nanonet-skin-layer and porous starch matrix	813:868	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	4	64	theme	percolation	1080:1090	arg1	flux					1092:1095	high percolation flux	1075:1095	high percolation flux (maximum of 15968 L m-2 h-1)	1075:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	64	theme	percolation	1080:1090	arg1	efficiency					1047:1056	excellent separation efficiency	1026:1056	excellent separation efficiency (up to 99.996%)	1026:1072	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	5	65	theme	property	1267:1274	arg1	advantage					1216:1224	the advantage	1212:1224	the advantage of biodegradability and anti-oil-fouling property	1212:1274	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	2	66	theme	eco-friendly	426:437	arg1	membrane					439:446	an eco-friendly membrane	423:446	an eco-friendly membrane with biomimetic cobweb-like nanostructure	423:488	Herein, we create an eco-friendly membrane with biomimetic cobweb-like nanostructure via assembling two-dimensional bacterial cellulose nanonets on the starch nanofibrous membrane on a large scale.					
35405607	4	67	theme	high	1075:1078	arg1	flux					1092:1095	high percolation flux	1075:1095	high percolation flux (maximum of 15968 L m-2 h-1)	1075:1124	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	4	67	theme	high	1075:1078	arg1	efficiency					1047:1056	excellent separation efficiency	1026:1056	excellent separation efficiency (up to 99.996%)	1026:1072	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	0	68	theme	high-flux	67:75	arg1	separation					108:117	high-flux and highly-efficient oil/water separation	67:117	high-flux and highly-efficient oil/water separation	67:117	Biodegradable, biomimetic, and nanonet-engineered membranes enable high-flux and highly-efficient oil/water separation.					
35405607	5	69	theme	biodegradability	1229:1244	arg1	advantage					1216:1224	the advantage	1212:1224	the advantage of biodegradability and anti-oil-fouling property	1212:1274	More significantly, with the advantage of biodegradability and anti-oil-fouling property, the membrane could serve as the robust platform for long-term wastewater remediation.					
35405607	3	70	theme	ultrahigh	697:705	arg1	porosity					707:714	ultrahigh porosity	697:714	ultrahigh porosity	697:714	The obtained novel composite membranes exhibit integrated properties of sub-micron pore size, ultrahigh porosity, superhydrophilicity, and underwater superoleophobicity, stemming from the synergistic effect of the hydrated nanonet-skin-layer and porous starch matrix.					
35405607	1	71	theme	tunable	181:187	arg1	architecture					196:207	tunable porous architecture	181:207	tunable porous architecture	181:207	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	4	72	theme	conventional	1147:1158	arg1	membranes					1176:1184	the conventional microfiltration membranes	1143:1184	the conventional microfiltration membranes	1143:1184	By virtue of the narrow-distributed sub-micron pores, ultrahigh porosity, and ultrathin thickness, the resulting membrane shows outstanding performance of excellent separation efficiency (up to 99.996%), high percolation flux (maximum of 15968 L m-2 h-1), well surpassing the conventional microfiltration membranes.					
35405607	1	73	theme	serious	276:282	arg1	problem					396:402	a thorny problem	387:402	a thorny problem	387:402	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
35405607	1	73	theme	serious	276:282	arg1	pollution					301:309	the serious secondary marine pollution	272:309	the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves	272:376	Porous membranes with fascinating super-wettable surface and tunable porous architecture for oil-water separation have been developed rapidly, however, the serious secondary marine pollution caused by the non-degradable defectiveness of membranes themselves is still a thorny problem.					
36634795	3	0	theme	water	755:759	arg1	permeability					767:778	reduced water vapor permeability	747:778	reduced water vapor permeability	747:778	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	1	1	link	scale-derived	267:279	arg1	FSG					290:292	FSG	290:292	FSG	290:292	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	1	link	scale-derived	267:279	arg1	gelatin					281:287	waste fish scale-derived gelatin	256:287	waste fish scale-derived gelatin (FSG)	256:293	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	4	2	theme	%	950:950	arg1	rate					936:939	DPPH radical scavenging rate	912:939	DPPH radical scavenging rate of 92.35 %	912:950	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	4	3	theme	CV	1077:1078	arg1	release					1066:1072	slow release	1061:1072	slow release of CV from composite film	1061:1098	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	1	4	theme	sodium	296:301	arg1	alginate					303:310	sodium alginate	296:310	sodium alginate (SA)	296:315	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	4	theme	sodium	296:301	arg1	SA					313:314	SA	313:314	SA	313:314	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	5	theme	ZIF-8	102:106	arg1	characterization					16:31	characterization	16:31	characterization	16:31	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	0	5	theme	ZIF-8	102:106	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	5	6	theme	preservation	1112:1123	arg1	experiment					1125:1134	Strawberry preservation experiment	1101:1134	Strawberry preservation experiment	1101:1134	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	4	7	theme	DPPH	912:915	arg1	rate					936:939	DPPH radical scavenging rate	912:939	DPPH radical scavenging rate of 92.35 %	912:950	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	1	8	theme	antibacterial	462:474	arg1	activity					476:483	sustained antibacterial activity	452:483	sustained antibacterial activity	452:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	5	9	theme	@	1159:1159	arg1	film					1166:1169	FSG/SA/CV@ZIF-8 film	1150:1169	FSG/SA/CV@ZIF-8 film	1150:1169	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	4	10	theme	radical	917:923	arg1	rate					936:939	DPPH radical scavenging rate	912:939	DPPH radical scavenging rate of 92.35 %	912:950	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	5	11	theme	ZIF-8	1160:1164	arg1	film					1166:1169	FSG/SA/CV@ZIF-8 film	1150:1169	FSG/SA/CV@ZIF-8 film	1150:1169	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	3	12	theme	film	829:832	arg1	stability					806:814	the thermal stability	794:814	the thermal stability of composite film	794:832	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	1	13	theme	activity	476:483	arg1	capable					441:447	capable	441:447	capable	441:447	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	4	14	theme	composite	1085:1093	arg1	film					1095:1098	composite film	1085:1098	composite film	1085:1098	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	0	15	theme	composite	122:130	arg1	films					132:136	composite films	122:136	composite films with sustained antibacterial activity for active food packaging	122:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	4	16	theme	scavenging	925:934	arg1	rate					936:939	DPPH radical scavenging rate	912:939	DPPH radical scavenging rate of 92.35 %	912:950	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	5	17	theme	preservation	1387:1398	arg1	packaging					1400:1408	food preservation packaging	1382:1408	food preservation packaging	1382:1408	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	0	18	theme	sustained	143:151	arg1	activity					167:174	sustained antibacterial activity	143:174	sustained antibacterial activity for active food packaging	143:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	4	19	theme	antioxidant	886:896	arg1	activity					898:905	strong antioxidant activity	879:905	strong antioxidant activity	879:905	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	3	20	from	break	710:714	arg1	elongation					696:705	the elongation	692:705	the elongation at break	692:714	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	3	20	from	break	710:714	arg1	blocking					679:686	the UV-light blocking	666:686	the UV-light blocking	666:686	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	1	21	theme	environmental-friendly	206:227	arg1	films					239:243	An environmental-friendly composite films	203:243	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles	203:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	2	22	theme	microstructure	490:503	arg1	films					569:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	3	23	theme	vapor	761:765	arg1	permeability					767:778	reduced water vapor permeability	747:778	reduced water vapor permeability	747:778	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	2	24	theme	properties	525:534	arg1	films					569:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	5	25	theme	prolonged	1277:1285	arg1	shelf-life					1287:1296	the prolonged shelf-life	1273:1296	the prolonged shelf-life of 8 days under ambient condition	1273:1330	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	1	26	theme	composite	229:237	arg1	films					239:243	An environmental-friendly composite films	203:243	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles	203:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	2	27	theme	physicochemical	509:523	arg1	properties					525:534	physicochemical properties	509:534	physicochemical properties of the FSG/SA/CV@ZIF-8	509:557	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	5	28	theme	spoilage	1236:1243	arg1	microorganism					1245:1257	spoilage microorganism	1236:1257	spoilage microorganism	1236:1257	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	0	29	link	scale-derived	47:59	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	3	30	theme	@	617:617	arg1	ZIF-8					618:622	CV@ZIF-8	615:622	CV@ZIF-8	615:622	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	3	31	theme	thermal	798:804	arg1	stability					806:814	the thermal stability	794:814	the thermal stability of composite film	794:832	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	0	32	with	films	132:136	arg1	activity					167:174	sustained antibacterial activity	143:174	sustained antibacterial activity for active food packaging	143:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	3	33	theme	ZIF-8	618:622	arg1	incorporation					598:610	The incorporation	594:610	The incorporation of CV@ZIF-8 into FSG/SA matrix	594:641	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	5	34	theme	application	1358:1368	arg1	prospect					1370:1377	its promising application prospect	1344:1377	its promising application prospect	1344:1377	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	5	35	theme	Strawberry	1101:1110	arg1	experiment					1125:1134	Strawberry preservation experiment	1101:1134	Strawberry preservation experiment	1101:1134	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	3	36	theme	FSG/SA	629:634	arg1	matrix					636:641	FSG/SA matrix	629:641	FSG/SA matrix	629:641	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	1	37	theme	waste	256:260	arg1	FSG					290:292	FSG	290:292	FSG	290:292	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	37	theme	waste	256:260	arg1	gelatin					281:287	waste fish scale-derived gelatin	256:287	waste fish scale-derived gelatin (FSG)	256:293	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	38	theme	antibacterial	153:165	arg1	activity					167:174	sustained antibacterial activity	143:174	sustained antibacterial activity for active food packaging	143:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	39	contain	containing	245:254	arg1	films					239:243	An environmental-friendly composite films	203:243	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles	203:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	39	contain	containing	245:254	arg2	gelatin					281:287	waste fish scale-derived gelatin	256:287	waste fish scale-derived gelatin (FSG)	256:293	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	39	contain	containing	245:254	arg2	alginate					303:310	sodium alginate	296:310	sodium alginate (SA)	296:315	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	39	contain	containing	245:254	arg2	carvacrol					321:329	carvacrol	321:329	carvacrol	321:329	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	39	contain	containing	245:254	arg2	SA					313:314	SA	313:314	SA	313:314	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	39	contain	containing	245:254	arg2	FSG					290:292	FSG	290:292	FSG	290:292	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	3	40	theme	CV	615:616	arg1	ZIF-8					618:622	CV@ZIF-8	615:622	CV@ZIF-8	615:622	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	5	41	theme	ambient	1314:1320	arg1	condition					1322:1330	ambient condition	1314:1330	ambient condition	1314:1330	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	1	42	theme	fish	262:265	arg1	FSG					290:292	FSG	290:292	FSG	290:292	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	42	theme	fish	262:265	arg1	gelatin					281:287	waste fish scale-derived gelatin	256:287	waste fish scale-derived gelatin (FSG)	256:293	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	43	theme	fish	42:45	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	44	theme	loaded	331:336	arg1	nanoparticles					355:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	45	theme	active	180:185	arg1	packaging					192:200	active food packaging	180:200	active food packaging	180:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	46	theme	active	409:414	arg1	materials					431:439	active food packaging materials	409:439	active food packaging materials capable of sustained antibacterial activity	409:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	5	47	theme	food	1382:1385	arg1	packaging					1400:1408	food preservation packaging	1382:1408	food preservation packaging	1382:1408	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	1	48	theme	scale-derived	267:279	arg1	FSG					290:292	FSG	290:292	FSG	290:292	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	48	theme	scale-derived	267:279	arg1	gelatin					281:287	waste fish scale-derived gelatin	256:287	waste fish scale-derived gelatin (FSG)	256:293	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	49	theme	waste	36:40	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	50	theme	ZIF-8	338:342	arg1	nanoparticles					355:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	2	51	theme	composite	559:567	arg1	films					569:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films	486:573	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	1	52	theme	food	416:419	arg1	materials					431:439	active food packaging materials	409:439	active food packaging materials capable of sustained antibacterial activity	409:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	2	53	theme	ZIF-8	553:557	arg1	microstructure					490:503	microstructure	490:503	microstructure	490:503	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	2	53	theme	ZIF-8	553:557	arg1	properties					525:534	physicochemical properties	509:534	physicochemical properties of the FSG/SA/CV@ZIF-8	509:557	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	0	54	theme	gelatin/sodium	61:74	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	2	55	theme	@	552:552	arg1	ZIF-8					553:557	the FSG/SA/CV@ZIF-8	539:557	the FSG/SA/CV@ZIF-8	539:557	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	1	56	theme	packaging	421:429	arg1	materials					431:439	active food packaging materials	409:439	active food packaging materials capable of sustained antibacterial activity	409:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	5	57	theme	FSG/SA/CV	1150:1158	arg1	film					1166:1169	FSG/SA/CV@ZIF-8 film	1150:1169	FSG/SA/CV@ZIF-8 film	1150:1169	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	0	58	theme	scale-derived	47:59	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	59	theme	CV	345:346	arg1	ZIF-8					348:352	CV@ZIF-8	345:352	CV@ZIF-8	345:352	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	59	theme	CV	345:346	arg1	ZIF-8					338:342	ZIF-8	338:342	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	0	60	theme	food	187:190	arg1	packaging					192:200	active food packaging	180:200	active food packaging	180:200	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	3	61	theme	water	726:730	arg1	resistance					732:741	water resistance	726:741	water resistance	726:741	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	5	62	theme	texture	1187:1193	arg1	deterioration					1195:1207	the texture deterioration	1183:1207	the texture deterioration	1183:1207	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	4	63	theme	slow	1061:1064	arg1	release					1066:1072	slow release	1061:1072	slow release of CV from composite film	1061:1098	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	4	64	theme	antibacterial	1002:1014	arg1	ability					1016:1022	the satisfactory and long-acting antibacterial ability	969:1022	the satisfactory and long-acting antibacterial ability	969:1022	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	1	65	theme	@	347:347	arg1	ZIF-8					348:352	CV@ZIF-8	345:352	CV@ZIF-8	345:352	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	65	theme	@	347:347	arg1	ZIF-8					338:342	ZIF-8	338:342	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	1	66	theme	capable	441:447	arg1	materials					431:439	active food packaging materials	409:439	active food packaging materials capable of sustained antibacterial activity	409:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	3	67	theme	UV-light	670:677	arg1	blocking					679:686	the UV-light blocking	666:686	the UV-light blocking	666:686	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	4	68	theme	strong	879:884	arg1	activity					898:905	strong antioxidant activity	879:905	strong antioxidant activity	879:905	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	3	69	theme	composite	819:827	arg1	film					829:832	composite film	819:832	composite film	819:832	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	1	70	dep	gelatin	281:287	arg1	nanoparticles					355:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	loaded ZIF-8 (CV@ZIF-8) nanoparticles	331:367	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	5	71	theme	microorganism	1245:1257	arg1	growth					1226:1231	the growth	1222:1231	the growth of spoilage microorganism	1222:1257	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	2	72	theme	FSG/SA/CV	543:551	arg1	ZIF-8					553:557	the FSG/SA/CV@ZIF-8	539:557	the FSG/SA/CV@ZIF-8	539:557	The microstructure and physicochemical properties of the FSG/SA/CV@ZIF-8 composite films were investigated.					
36634795	4	73	theme	FSG/SA/CV	839:847	arg1	film					855:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	0	74	theme	loaded	95:100	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	1	75	theme	sustained	452:460	arg1	activity					476:483	sustained antibacterial activity	452:483	sustained antibacterial activity	452:483	An environmental-friendly composite films containing waste fish scale-derived gelatin (FSG), sodium alginate (SA) and carvacrol loaded ZIF-8 (CV@ZIF-8) nanoparticles were designed and fabricated to develop active food packaging materials capable of sustained antibacterial activity.					
36634795	4	76	theme	ZIF-8	849:853	arg1	film					855:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	4	77	from	film	1095:1098	arg1	release					1066:1072	slow release	1061:1072	slow release of CV from composite film	1061:1098	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	5	78	theme	promising	1348:1356	arg1	prospect					1370:1377	its promising application prospect	1344:1377	its promising application prospect	1344:1377	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	0	79	theme	alginate/carvacrol	76:93	arg1	ZIF-8					102:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8	36:106	Fabrication and characterization of waste fish scale-derived gelatin/sodium alginate/carvacrol loaded ZIF-8 nanoparticles composite films with sustained antibacterial activity for active food packaging.					
36634795	3	80	theme	reduced	747:753	arg1	permeability					767:778	reduced water vapor permeability	747:778	reduced water vapor permeability	747:778	The incorporation of CV@ZIF-8 into FSG/SA matrix significantly enhanced the UV-light blocking and the elongation at break, improved water resistance and reduced water vapor permeability, and improved the thermal stability of composite film.					
36634795	4	81	theme	@	848:848	arg1	film					855:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film	835:858	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	4	82	theme	long-acting	990:1000	arg1	ability					1016:1022	the satisfactory and long-acting antibacterial ability	969:1022	the satisfactory and long-acting antibacterial ability	969:1022	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
36634795	5	83	theme	8 days	1301:1306	arg1	shelf-life					1287:1296	the prolonged shelf-life	1273:1296	the prolonged shelf-life of 8 days under ambient condition	1273:1330	Strawberry preservation experiment revealed that FSG/SA/CV@ZIF-8 film decelerated the texture deterioration and retarded the growth of spoilage microorganism, resulting in the prolonged shelf-life of 8 days under ambient condition, indicating its promising application prospect in food preservation packaging.					
36634795	4	84	theme	satisfactory	973:984	arg1	ability					1016:1022	the satisfactory and long-acting antibacterial ability	969:1022	the satisfactory and long-acting antibacterial ability	969:1022	The FSG/SA/CV@ZIF-8 film not only exhibited strong antioxidant activity with DPPH radical scavenging rate of 92.35 %, but also showed the satisfactory and long-acting antibacterial ability against E. coli and S. aureus due to slow release of CV from composite film.					
37331534	8	0	theme	CNF	1286:1288	arg1	aerogel					1290:1296	Pure CNF aerogel	1281:1296	Pure CNF aerogel	1281:1296	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	1	1	theme	insulating	177:186	arg1	materials					188:196	naturally available thermal insulating materials	149:196	naturally available thermal insulating materials	149:196	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	2	theme	low	283:285	arg1	sources					274:280	their extensive sources	258:280	their extensive sources	258:280	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	2	theme	low	283:285	arg1	density					287:293	low density	283:293	low density	283:293	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	5	3	theme	TPMPAT	724:729	arg1	addition					712:719	the addition	708:719	the addition of TPMPAT and/or PDMS	708:741	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	9	4	theme	fire	1531:1534	arg1	resistance					1536:1545	high fire resistance	1526:1545	high fire resistance	1526:1545	In contrast, both TPMPAT/CNF-30 % and PDMS-TPMPAT/CNF-30 % showed self-extinction behaviors with a UL-94 V-0 grade, implying high fire resistance.					
37331534	7	5	theme	TPMPAT/CNF	1166:1175	arg1	aerogel					1177:1183	TPMPAT/CNF aerogel	1166:1183	TPMPAT/CNF aerogel modified by PDMS	1166:1200	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	10	6	theme	great	1653:1657	arg1	potential					1659:1667	great potential	1653:1667	great potential for thermal insulation applications	1653:1703	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	5	7	dep	density	766:772	arg1	the					762:764	the	762:764	the	762:764	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	5	8	theme	composite	806:814	arg1	aerogels					816:823	the composite aerogels	802:823	the composite aerogels	802:823	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	5	9	theme	PDMS	738:741	arg1	addition					712:719	the addition	708:719	the addition of TPMPAT and/or PDMS	708:741	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	2	10	theme	high	400:403	arg1	flammability					405:416	high flammability	400:416	high flammability	400:416	However, cellulosic aerogels suffer from high flammability and hygroscopicity.					
37331534	6	11	dep	had	984:986	arg1	indicated					1024:1032	indicated	1024:1032	indicated that the modified cellulose aerogels have better thermal stability	1024:1099	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	1	12	theme	low	296:298	arg1	sources					274:280	their extensive sources	258:280	their extensive sources	258:280	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	12	theme	low	296:298	arg1	conductivity					308:319	low thermal conductivity	296:319	low thermal conductivity	296:319	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	5	13	theme	aerogels	816:823	arg1	density					766:772	density	766:772	density	766:772	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	5	13	theme	aerogels	816:823	arg1	conductivity					786:797	thermal conductivity	778:797	thermal conductivity	778:797	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	9	14	theme	UL-94 V-0	1500:1508	arg1	grade					1510:1514	a UL-94 V-0 grade	1498:1514	a UL-94 V-0 grade	1498:1514	In contrast, both TPMPAT/CNF-30 % and PDMS-TPMPAT/CNF-30 % showed self-extinction behaviors with a UL-94 V-0 grade, implying high fire resistance.					
37331534	6	15	contain	have	1071:1074	arg1	aerogels					1062:1069	the modified cellulose aerogels	1039:1069	the modified cellulose aerogels	1039:1069	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	15	contain	have	1071:1074	arg2	stability					1091:1099	better thermal stability	1076:1099	better thermal stability	1076:1099	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	8	16	theme	Pure	1281:1284	arg1	aerogel					1290:1296	Pure CNF aerogel	1281:1296	Pure CNF aerogel	1281:1296	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	5	17	theme	commercial	868:877	arg1	aerogels					889:896	the commercial polymeric aerogels	864:896	the commercial polymeric aerogels	864:896	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	6	18	dep	higher	988:993	arg1	Tmax					1012:1015	Tmax	1012:1015	Tmax	1012:1015	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	18	dep	higher	988:993	arg1	%					999:999	T-10%	995:999	T-10%	995:999	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	18	dep	higher	988:993	arg1	%					1006:1006	T-50%	1002:1006	T-50%	1002:1006	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	19	theme	modified	1043:1050	arg1	aerogels					1062:1069	the modified cellulose aerogels	1039:1069	the modified cellulose aerogels	1039:1069	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	9	20	theme	high	1526:1529	arg1	resistance					1536:1545	high fire resistance	1526:1545	high fire resistance	1526:1545	In contrast, both TPMPAT/CNF-30 % and PDMS-TPMPAT/CNF-30 % showed self-extinction behaviors with a UL-94 V-0 grade, implying high fire resistance.					
37331534	6	21	contain	had	984:986	arg2	higher					988:993	higher	988:993	higher	988:993	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	21	contain	had	984:986	arg1	aerogel					945:951	the cellulose aerogel	931:951	the cellulose aerogel modified by TPMPAT and/or PDMS	931:982	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	5	22	theme	polymeric	879:887	arg1	aerogels					889:896	the commercial polymeric aerogels	864:896	the commercial polymeric aerogels	864:896	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	1	23	theme	Cellulosic	108:117	arg1	aerogels					119:126	Cellulosic aerogels	108:126	Cellulosic aerogels (CNF)	108:132	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	23	theme	Cellulosic	108:117	arg1	CNF					129:131	CNF	129:131	CNF	129:131	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	7	24	theme	TPMPAT	1102:1107	arg1	modification					1109:1120	TPMPAT modification	1102:1120	TPMPAT modification	1102:1120	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	3	25	theme	P/N-containing	460:473	arg1	retardant					481:489	a novel P/N-containing flame retardant	452:489	a novel P/N-containing flame retardant (TPMPAT)	452:498	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	3	25	theme	P/N-containing	460:473	arg1	TPMPAT					492:497	TPMPAT	492:497	TPMPAT	492:497	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	0	26	theme	Ultra-light-weight	0:17	arg1	aerogels					62:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels	0:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.	0:106	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	1	27	theme	thermal	300:306	arg1	sources					274:280	their extensive sources	258:280	their extensive sources	258:280	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	27	theme	thermal	300:306	arg1	conductivity					308:319	low thermal conductivity	296:319	low thermal conductivity	296:319	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	7	28	theme	hydrophilic	1147:1157	arg1	aerogels					1131:1138	CNF aerogels	1127:1138	CNF aerogels highly hydrophilic	1127:1157	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	7	29	with	material	1230:1237	arg1	angle					1260:1264	a water contact angle	1244:1264	a water contact angle (WCA) of 142°	1244:1278	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	7	29	with	material	1230:1237	arg1	WCA					1267:1269	WCA	1267:1269	WCA	1267:1269	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	3	30	theme	flame	475:479	arg1	retardant					481:489	a novel P/N-containing flame retardant	452:489	a novel P/N-containing flame retardant (TPMPAT)	452:498	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	3	30	theme	flame	475:479	arg1	TPMPAT					492:497	TPMPAT	492:497	TPMPAT	492:497	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	7	31	theme	hydrophobic	1218:1228	arg1	material					1230:1237	a highly hydrophobic material	1209:1237	a highly hydrophobic material with a water contact angle (WCA) of 142°	1209:1278	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	8	32	theme	low	1339:1341	arg1	LOI					1366:1368	LOI	1366:1368	LOI	1366:1368	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	8	32	theme	low	1339:1341	arg1	index					1359:1363	a low limiting oxygen index	1337:1363	a low limiting oxygen index (LOI) of 23.0 %	1337:1379	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	7	33	theme	CNF	1127:1129	arg1	aerogels					1131:1138	CNF aerogels	1127:1138	CNF aerogels highly hydrophilic	1127:1157	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	8	34	theme	UL-94	1388:1392	arg1	grade					1394:1398	no UL-94 grade	1385:1398	no UL-94 grade	1385:1398	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	1	35	theme	polymeric	230:238	arg1	aerogels					240:247	conventional polymeric aerogels	217:247	conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability	217:356	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	0	36	theme	anti-flammable	20:33	arg1	aerogels					62:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels	0:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.	0:106	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	5	37	theme	thermal	778:784	arg1	conductivity					786:797	thermal conductivity	778:797	thermal conductivity	778:797	Although the addition of TPMPAT and/or PDMS slightly increased the density and thermal conductivity of the composite aerogels, those values were still comparable to the commercial polymeric aerogels.					
37331534	10	38	theme	high	1562:1565	arg1	anti-flammability					1567:1583	high anti-flammability	1562:1583	high anti-flammability	1562:1583	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	8	39	theme	oxygen	1352:1357	arg1	LOI					1366:1368	LOI	1366:1368	LOI	1366:1368	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	8	39	theme	oxygen	1352:1357	arg1	index					1359:1363	a low limiting oxygen index	1337:1363	a low limiting oxygen index (LOI) of 23.0 %	1337:1379	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	0	40	theme	cellulosic	51:60	arg1	aerogels					62:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels	0:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.	0:106	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	6	41	theme	cellulose	935:943	arg1	aerogel					945:951	the cellulose aerogel	931:951	the cellulose aerogel modified by TPMPAT and/or PDMS	931:982	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	1	42	theme	conventional	217:228	arg1	aerogels					240:247	conventional polymeric aerogels	217:247	conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability	217:356	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	0	43	theme	water-proof	39:49	arg1	aerogels					62:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels	0:69	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.	0:106	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	4	44	theme	TPMPAT/CNF	582:591	arg1	aerogels					593:600	TPMPAT/CNF aerogels	582:600	TPMPAT/CNF aerogels	582:600	TPMPAT/CNF aerogels were further modified by polydimethylsiloxane (PDMS) to enhance the water-proof characteristics.					
37331534	3	45	theme	novel	454:458	arg1	retardant					481:489	a novel P/N-containing flame retardant	452:489	a novel P/N-containing flame retardant (TPMPAT)	452:498	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	3	45	theme	novel	454:458	arg1	TPMPAT					492:497	TPMPAT	492:497	TPMPAT	492:497	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	10	46	theme	cellulosic	1628:1637	arg1	aerogels					1639:1646	the ultra-light-weight cellulosic aerogels	1605:1646	the ultra-light-weight cellulosic aerogels	1605:1646	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	6	47	theme	thermal	1083:1089	arg1	stability					1091:1099	better thermal stability	1076:1099	better thermal stability	1076:1099	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	10	48	theme	insulation	1681:1690	arg1	applications					1692:1703	thermal insulation applications	1673:1703	thermal insulation applications	1673:1703	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	7	49	theme	142°	1275:1278	arg1	angle					1260:1264	a water contact angle	1244:1264	a water contact angle (WCA) of 142°	1244:1278	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	7	49	theme	142°	1275:1278	arg1	WCA					1267:1269	WCA	1267:1269	WCA	1267:1269	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	8	50	theme	%	1379:1379	arg1	grade					1394:1398	no UL-94 grade	1385:1398	no UL-94 grade	1385:1398	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	8	50	theme	%	1379:1379	arg1	index					1359:1363	a low limiting oxygen index	1337:1363	a low limiting oxygen index (LOI) of 23.0 %	1337:1379	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	8	50	theme	%	1379:1379	arg1	LOI					1366:1368	LOI	1366:1368	LOI	1366:1368	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	3	51	theme	cellulosic	526:535	arg1	aerogels					537:544	cellulosic aerogels	526:544	cellulosic aerogels	526:544	In this work, a novel P/N-containing flame retardant (TPMPAT) was synthesized to modify cellulosic aerogels to improve their anti-flammability.					
37331534	4	52	mod	modified	615:622	arg1	aerogels					593:600	TPMPAT/CNF aerogels	582:600	TPMPAT/CNF aerogels	582:600	TPMPAT/CNF aerogels were further modified by polydimethylsiloxane (PDMS) to enhance the water-proof characteristics.					
37331534	4	52	mod	modified	615:622	arg3	polydimethylsiloxane					627:646	polydimethylsiloxane	627:646	polydimethylsiloxane (PDMS)	627:653	TPMPAT/CNF aerogels were further modified by polydimethylsiloxane (PDMS) to enhance the water-proof characteristics.					
37331534	4	52	mod	modified	615:622	arg3	PDMS					649:652	PDMS	649:652	PDMS	649:652	TPMPAT/CNF aerogels were further modified by polydimethylsiloxane (PDMS) to enhance the water-proof characteristics.					
37331534	7	53	theme	contact	1252:1258	arg1	angle					1260:1264	a water contact angle	1244:1264	a water contact angle (WCA) of 142°	1244:1278	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	7	53	theme	contact	1252:1258	arg1	WCA					1267:1269	WCA	1267:1269	WCA	1267:1269	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	10	54	theme	thermal	1673:1679	arg1	applications					1692:1703	thermal insulation applications	1673:1703	thermal insulation applications	1673:1703	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	6	55	theme	CNF	918:920	arg1	aerogel					922:928	pure CNF aerogel	913:928	pure CNF aerogel	913:928	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	2	56	theme	cellulosic	368:377	arg1	aerogels					379:386	cellulosic aerogels	368:386	cellulosic aerogels	368:386	However, cellulosic aerogels suffer from high flammability and hygroscopicity.					
37331534	6	57	theme	better	1076:1081	arg1	stability					1091:1099	better thermal stability	1076:1099	better thermal stability	1076:1099	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	6	58	theme	pure	913:916	arg1	aerogel					922:928	pure CNF aerogel	913:928	pure CNF aerogel	913:928	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	8	59	theme	limiting	1343:1350	arg1	LOI					1366:1368	LOI	1366:1368	LOI	1366:1368	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	8	59	theme	limiting	1343:1350	arg1	index					1359:1363	a low limiting oxygen index	1337:1363	a low limiting oxygen index (LOI) of 23.0 %	1337:1379	Pure CNF aerogel burned rapidly after ignition, showing a low limiting oxygen index (LOI) of 23.0 % and no UL-94 grade.					
37331534	1	60	theme	extensive	264:272	arg1	sources					274:280	their extensive sources	258:280	their extensive sources	258:280	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	60	theme	extensive	264:272	arg1	biodegradability					341:356	biodegradability	341:356	biodegradability	341:356	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	60	theme	extensive	264:272	arg1	sustainability					322:335	sustainability	322:335	sustainability	322:335	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	60	theme	extensive	264:272	arg1	conductivity					308:319	low thermal conductivity	296:319	low thermal conductivity	296:319	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	1	60	theme	extensive	264:272	arg1	density					287:293	low density	283:293	low density	283:293	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	0	61	theme	insulation	83:92	arg1	applications					94:105	thermal insulation applications	75:105	thermal insulation applications	75:105	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	9	62	theme	self-extinction	1467:1481	arg1	behaviors					1483:1491	self-extinction behaviors	1467:1491	self-extinction behaviors	1467:1491	In contrast, both TPMPAT/CNF-30 % and PDMS-TPMPAT/CNF-30 % showed self-extinction behaviors with a UL-94 V-0 grade, implying high fire resistance.					
37331534	1	63	theme	available	159:167	arg1	materials					188:196	naturally available thermal insulating materials	149:196	naturally available thermal insulating materials	149:196	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	0	64	theme	thermal	75:81	arg1	applications					94:105	thermal insulation applications	75:105	thermal insulation applications	75:105	Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.					
37331534	7	65	theme	water	1246:1250	arg1	angle					1260:1264	a water contact angle	1244:1264	a water contact angle (WCA) of 142°	1244:1278	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	7	65	theme	water	1246:1250	arg1	WCA					1267:1269	WCA	1267:1269	WCA	1267:1269	TPMPAT modification made CNF aerogels highly hydrophilic, while TPMPAT/CNF aerogel modified by PDMS became a highly hydrophobic material with a water contact angle (WCA) of 142°.					
37331534	6	66	theme	cellulose	1052:1060	arg1	aerogels					1062:1069	the modified cellulose aerogels	1039:1069	the modified cellulose aerogels	1039:1069	Compared with pure CNF aerogel, the cellulose aerogel modified by TPMPAT and/or PDMS had higher T-10%, T-50% and Tmax, which indicated that the modified cellulose aerogels have better thermal stability.					
37331534	10	67	theme	ultra-light-weight	1609:1626	arg1	aerogels					1639:1646	the ultra-light-weight cellulosic aerogels	1605:1646	the ultra-light-weight cellulosic aerogels	1605:1646	Combined with high anti-flammability and hydrophobicity, the ultra-light-weight cellulosic aerogels show great potential for thermal insulation applications.					
37331534	1	68	theme	thermal	169:175	arg1	materials					188:196	naturally available thermal insulating materials	149:196	naturally available thermal insulating materials	149:196	Cellulosic aerogels (CNF) are considered naturally available thermal insulating materials as substitutes for conventional polymeric aerogels owing to their extensive sources, low density, low thermal conductivity, sustainability and biodegradability.					
37331534	4	69	theme	water-proof	670:680	arg1	characteristics					682:696	the water-proof characteristics	666:696	the water-proof characteristics	666:696	TPMPAT/CNF aerogels were further modified by polydimethylsiloxane (PDMS) to enhance the water-proof characteristics.					
37236566	7	0	theme	removal	1053:1059	arg1	efficiency					1061:1070	the removal efficiency	1049:1070	the removal efficiency	1049:1070	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	3	1	theme	bio-surfactant	474:487	arg1	exfoliation					500:510	bio-surfactant in in-situ exfoliation	474:510	bio-surfactant in in-situ exfoliation of graphite to FLG	474:529	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	3	2	theme	in	489:490	arg1	exfoliation					500:510	bio-surfactant in in-situ exfoliation	474:510	bio-surfactant in in-situ exfoliation of graphite to FLG	474:529	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	5	3	theme	removal	703:709	arg1	capacity					675:682	sorption capacity	666:682	sorption capacity	666:682	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	5	3	theme	removal	703:709	arg1	Qe					685:686	Qe	685:686	Qe	685:686	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	5	3	theme	removal	703:709	arg1	efficiency					651:660	efficiency	651:660	efficiency	651:660	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	3	4	theme	few-layer	377:385	arg1	beads					405:409	few-layer graphene (FLG/BA) beads	377:409	few-layer graphene (FLG/BA) beads	377:409	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	2	5	theme	adsorbing	288:296	arg1	materials					298:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	Dedicated to this issue, developing high-performance, sustainable, and bio-compatible adsorbing materials is still challenging.					
37236566	6	6	theme	enthalpy	863:870	arg1	ΔH°					880:882	ΔH°	880:882	ΔH°	880:882	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	6	theme	enthalpy	863:870	arg1	change					872:877	the enthalpy change	859:877	the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1	859:919	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	8	7	theme	higher	1241:1246	arg1	capacity					1259:1266	a higher adsorption capacity	1239:1266	a higher adsorption capacity of FLG/BA composite	1239:1286	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	2	8	theme	bio-compatible	273:286	arg1	materials					298:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	Dedicated to this issue, developing high-performance, sustainable, and bio-compatible adsorbing materials is still challenging.					
37236566	4	9	theme	beads	575:579	arg1	characteristics					552:566	The physicochemical characteristics	532:566	The physicochemical characteristics of the beads	532:579	The physicochemical characteristics of the beads demonstrated an excess of barium chloride used as a cross-linker.					
37236566	3	10	theme	alginate	345:352	arg1	BA					355:356	barium alginate (BA)	338:357	barium alginate (BA)	338:357	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	7	11	from	cycle	1105:1109	arg1	cycle					1146:1150	the sixth cycle	1136:1150	the sixth cycle for BA and FLG/BA	1136:1168	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	7	12	theme	reusability	1031:1041	arg1	test					1043:1046	the reusability test	1027:1046	the reusability test	1027:1046	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	4	13	theme	chloride	614:621	arg1	excess					597:602	an excess	594:602	an excess of barium chloride used as a cross-linker	594:644	The physicochemical characteristics of the beads demonstrated an excess of barium chloride used as a cross-linker.					
37236566	5	14	theme	processing	725:734	arg1	duration					736:743	processing duration	725:743	processing duration	725:743	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	0	15	theme	few-layer-graphene/alginate	39:65	arg1	filter					85:90	a kidney filter	76:90	a kidney filter	76:90	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	0	15	theme	few-layer-graphene/alginate	39:65	arg1	beads					67:71	few-layer-graphene/alginate beads	39:71	few-layer-graphene/alginate beads	39:71	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	1	16	dep	such	122:125	arg1	as					127:128	as	127:128	as	127:128	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	6	17	theme	-36.11 kJ·mol-1	905:919	arg1	ΔS°					945:947	ΔS°	945:947	ΔS°	945:947	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	17	theme	-36.11 kJ·mol-1	905:919	arg1	change					937:942	the entropy change	925:942	the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively	925:1017	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	17	theme	-36.11 kJ·mol-1	905:919	arg1	ΔH°					880:882	ΔH°	880:882	ΔH°	880:882	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	17	theme	-36.11 kJ·mol-1	905:919	arg1	change					872:877	the enthalpy change	859:877	the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1	859:919	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	7	18	theme	sixth	1140:1144	arg1	cycle					1146:1150	the sixth cycle	1136:1150	the sixth cycle for BA and FLG/BA	1136:1168	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	8	19	theme	composite	1278:1286	arg1	capacity					1259:1266	a higher adsorption capacity	1239:1266	a higher adsorption capacity of FLG/BA composite	1239:1286	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	1	20	theme	common	171:176	arg1	diseases					192:199	the most common and dangerous diseases	162:199	the most common and dangerous diseases	162:199	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	0	21	theme	Performant	0:9	arg1	removal					11:17	Performant removal	0:17	Performant removal of creatinine	0:31	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	6	22	theme	entropy	929:935	arg1	ΔS°					945:947	ΔS°	945:947	ΔS°	945:947	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	22	theme	entropy	929:935	arg1	change					937:942	the entropy change	925:942	the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively	925:1017	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	3	23	dep	in	489:490	arg1	in-situ					492:498	in-situ	492:498	in-situ	492:498	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	0	24	theme	creatinine	22:31	arg1	removal					11:17	Performant removal	0:17	Performant removal of creatinine	0:31	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	8	25	theme	structure-property	1338:1355	arg1	relation					1357:1364	a strong structure-property relation	1329:1364	a strong structure-property relation	1329:1364	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	3	26	contain	containing	366:375	arg2	beads					405:409	few-layer graphene (FLG/BA) beads	377:409	few-layer graphene (FLG/BA) beads	377:409	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	3	26	contain	containing	366:375	arg1	BA					363:364	BA	363:364	BA containing few-layer graphene (FLG/BA) beads	363:409	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	1	27	theme	renal	106:110	arg1	function					112:119	renal function	106:119	renal function	106:119	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	3	28	theme	sodium	442:447	arg1	alginate					449:456	sodium alginate	442:456	sodium alginate	442:456	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	8	29	theme	FLG/BA	1271:1276	arg1	composite					1278:1286	FLG/BA composite	1271:1286	FLG/BA composite	1271:1286	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	6	30	theme	thermodynamic	827:839	arg1	parameters					841:850	The thermodynamic parameters	823:850	The thermodynamic parameters	823:850	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	1	31	theme	function	112:119	arg1	Reduction					93:101	Reduction	93:101	Reduction of renal function, such as creatinine adsorption	93:150	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	1	32	theme	diseases	192:199	arg1	diseases					192:199	the most common and dangerous diseases	162:199	the most common and dangerous diseases	162:199	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	1	32	theme	diseases	192:199	arg1	one					155:157	one	155:157	one	155:157	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	3	33	theme	FLG/BA	397:402	arg1	beads					405:409	few-layer graphene (FLG/BA) beads	377:409	few-layer graphene (FLG/BA) beads	377:409	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	4	34	theme	physicochemical	536:550	arg1	characteristics					552:566	The physicochemical characteristics	532:566	The physicochemical characteristics of the beads	532:579	The physicochemical characteristics of the beads demonstrated an excess of barium chloride used as a cross-linker.					
37236566	7	35	theme	optimal	1091:1097	arg1	cycle					1105:1109	the optimal first cycle	1087:1109	the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA	1087:1168	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	5	36	theme	creatinine	692:701	arg1	removal					703:709	creatinine removal	692:709	creatinine removal	692:709	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	5	37	dep	efficiency	651:660	arg1	The					647:649	The	647:649	The	647:649	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	7	38	theme	FLG/BA	1203:1208	arg1	stability					1190:1198	superior stability	1181:1198	superior stability of FLG/BA	1181:1208	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	3	39	theme	graphene	387:394	arg1	beads					405:409	few-layer graphene (FLG/BA) beads	377:409	few-layer graphene (FLG/BA) beads	377:409	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	6	40	theme	-24.29	894:899	arg1	ΔS°					945:947	ΔS°	945:947	ΔS°	945:947	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	40	theme	-24.29	894:899	arg1	change					937:942	the entropy change	925:942	the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively	925:1017	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	40	theme	-24.29	894:899	arg1	ΔH°					880:882	ΔH°	880:882	ΔH°	880:882	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	6	40	theme	-24.29	894:899	arg1	change					872:877	the enthalpy change	859:877	the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1	859:919	The thermodynamic parameters detect the enthalpy change (ΔH°) of about -24.29 and -36.11 kJ·mol-1 and the entropy change (ΔS°) of around -69.24 and -79.46 kJ·mol-1 for BA and FLG/BA, respectively.					
37236566	7	41	theme	superior	1181:1188	arg1	stability					1190:1198	superior stability	1181:1198	superior stability of FLG/BA	1181:1208	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	5	42	theme	sorption	666:673	arg1	capacity					675:682	sorption capacity	666:682	sorption capacity	666:682	The efficiency and sorption capacity (Qe) of creatinine removal increase with processing duration reaching 82.1, 99.5 %, and 68.4, 82.9 mg·g-1 for BA and FLG/BA, respectively.					
37236566	7	43	theme	first	1099:1103	arg1	cycle					1105:1109	the optimal first cycle	1087:1109	the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA	1087:1168	During the reusability test, the removal efficiency decreases from the optimal first cycle to 69.1 and to 88.3 % in the sixth cycle for BA and FLG/BA, revealing superior stability of FLG/BA.					
37236566	2	44	theme	sustainable	256:266	arg1	materials					298:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	Dedicated to this issue, developing high-performance, sustainable, and bio-compatible adsorbing materials is still challenging.					
37236566	3	45	from	alginate	449:456	arg1	water					431:435	water	431:435	water from sodium alginate	431:456	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	3	46	theme	graphite	515:522	arg1	exfoliation					500:510	bio-surfactant in in-situ exfoliation	474:510	bio-surfactant in in-situ exfoliation of graphite to FLG	474:529	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	8	47	theme	adsorption	1248:1257	arg1	capacity					1259:1266	a higher adsorption capacity	1239:1266	a higher adsorption capacity of FLG/BA composite	1239:1286	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	1	48	theme	creatinine	130:139	arg1	adsorption					141:150	creatinine adsorption	130:150	creatinine adsorption	130:150	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	0	49	theme	kidney	78:83	arg1	filter					85:90	a kidney filter	76:90	a kidney filter	76:90	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	0	49	theme	kidney	78:83	arg1	beads					67:71	few-layer-graphene/alginate beads	39:71	few-layer-graphene/alginate beads	39:71	Performant removal of creatinine using few-layer-graphene/alginate beads as a kidney filter.					
37236566	2	50	theme	high-performance	238:253	arg1	materials					298:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	high-performance, sustainable, and bio-compatible adsorbing materials	238:306	Dedicated to this issue, developing high-performance, sustainable, and bio-compatible adsorbing materials is still challenging.					
37236566	1	51	theme	dangerous	182:190	arg1	diseases					192:199	the most common and dangerous diseases	162:199	the most common and dangerous diseases	162:199	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	1	52	theme	adsorption	141:150	arg1	Reduction					93:101	Reduction	93:101	Reduction of renal function, such as creatinine adsorption	93:150	Reduction of renal function, such as creatinine adsorption is one of the most common and dangerous diseases.					
37236566	4	53	theme	barium	607:612	arg1	chloride					614:621	barium chloride	607:621	barium chloride used as a cross-linker	607:644	The physicochemical characteristics of the beads demonstrated an excess of barium chloride used as a cross-linker.					
37236566	3	54	theme	barium	338:343	arg1	BA					355:356	barium alginate (BA)	338:357	barium alginate (BA)	338:357	Herein, barium alginate (BA) and BA containing few-layer graphene (FLG/BA) beads were synthesized in water from sodium alginate, also acting as bio-surfactant in in-situ exfoliation of graphite to FLG.					
37236566	8	55	theme	strong	1331:1336	arg1	relation					1357:1364	a strong structure-property relation	1329:1364	a strong structure-property relation	1329:1364	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
37236566	8	56	theme	MD	1215:1216	arg1	calculations					1218:1229	The MD calculations	1211:1229	The MD calculations	1211:1229	The MD calculations confirm a higher adsorption capacity of FLG/BA composite compared to BA alone, clearly confirming a strong structure-property relation.					
36446851	0	0	theme	mechanical	73:82	arg1	properties					84:93	mechanical properties	73:93	mechanical properties	73:93	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	3	1	theme	electrostatic	604:616	arg1	repulsion					618:626	electrostatic repulsion	604:626	electrostatic repulsion	604:626	ChNF (0.075 wt%) and ChNC (0.05 wt%) retarded the final setting time by 50 and 30 min, likely through cement dispersion by electrostatic repulsion.					
36446851	2	2	theme	shell	315:319	arg1	waste					321:325	shrimp shell waste	308:325	shrimp shell waste	308:325	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	6	3	theme	Solid-state	837:847	arg1	NMR					877:879	NMR	877:879	NMR	877:879	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	3	theme	Solid-state	837:847	arg1	resonance					866:874	Solid-state nuclear magnetic resonance	837:874	Solid-state nuclear magnetic resonance (NMR)	837:880	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	4	4	with	ChNF	629:632	arg1	ratio					666:670	a larger aspect ratio	650:670	a larger aspect ratio than ChNC	650:680	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	3	5	theme	cement	583:588	arg1	dispersion					590:599	cement dispersion	583:599	cement dispersion by electrostatic repulsion	583:626	ChNF (0.075 wt%) and ChNC (0.05 wt%) retarded the final setting time by 50 and 30 min, likely through cement dispersion by electrostatic repulsion.					
36446851	2	6	theme	shrimp	308:313	arg1	waste					321:325	shrimp shell waste	308:325	shrimp shell waste	308:325	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	0	7	from	Impact	0:5	arg1	hydration					123:131	late-age hydration	114:131	late-age hydration	114:131	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	7	from	Impact	0:5	arg1	shells					63:68	waste shrimp shells	50:68	waste shrimp shells	50:68	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	7	from	Impact	0:5	arg1	properties					84:93	mechanical properties	73:93	mechanical properties	73:93	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	7	from	Impact	0:5	arg1	time					104:107	setting time	96:107	setting time	96:107	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	4	8	theme	larger	652:657	arg1	aspect					659:664	a larger aspect	650:664	a larger aspect ratio than ChNC	650:680	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	6	9	from	28 days	1064:1070	arg1	degree					967:972	a 41% higher degree	954:972	a 41% higher degree of polymerization	954:990	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	9	from	28 days	1064:1070	arg1	degree					1041:1046	a 15% higher degree	1028:1046	a 15% higher degree of hydration at 28 days	1028:1070	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	9	from	28 days	1064:1070	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	10	theme	more	996:999	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	11	theme	calcium-silicate-hydrate	914:937	arg1	structure					939:947	calcium-silicate-hydrate structure	914:947	calcium-silicate-hydrate structure	914:947	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	12	theme	nuclear	849:855	arg1	NMR					877:879	NMR	877:879	NMR	877:879	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	12	theme	nuclear	849:855	arg1	resonance					866:874	Solid-state nuclear magnetic resonance	837:874	Solid-state nuclear magnetic resonance (NMR)	837:880	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	7	13	theme	seafood	1220:1226	arg1	waste					1228:1232	seafood waste	1220:1232	seafood waste	1220:1232	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	1	14	theme	year ~ 6-8	150:159	arg1	tonnes					169:174	Every year ~ 6-8 million tonnes	144:174	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes	144:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	0	15	theme	setting	96:102	arg1	time					104:107	setting time	96:107	setting time	96:107	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	6	16	theme	hydration	1051:1059	arg1	degree					967:972	a 41% higher degree	954:972	a 41% higher degree of polymerization	954:990	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	16	theme	hydration	1051:1059	arg1	degree					1041:1046	a 15% higher degree	1028:1046	a 15% higher degree of hydration at 28 days	1028:1070	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	16	theme	hydration	1051:1059	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	4	17	theme	aspect	659:664	arg1	ratio					666:670	a larger aspect ratio	650:670	a larger aspect ratio than ChNC	650:680	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	1	18	theme	million	161:167	arg1	tonnes					169:174	Every year ~ 6-8 million tonnes	144:174	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes	144:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	1	19	theme	costly	243:248	arg1	procedures					259:268	costly disposal procedures	243:268	costly disposal procedures	243:268	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	6	20	theme	polymerization	977:990	arg1	degree					967:972	a 41% higher degree	954:972	a 41% higher degree of polymerization	954:990	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	20	theme	polymerization	977:990	arg1	degree					1041:1046	a 15% higher degree	1028:1046	a 15% higher degree of hydration at 28 days	1028:1070	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	20	theme	polymerization	977:990	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	0	21	theme	nanofibers	17:26	arg1	Impact					0:5	Impact	0:5	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.	0:142	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	1	22	theme	disposal	250:257	arg1	procedures					259:268	costly disposal procedures	243:268	costly disposal procedures	243:268	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	7	23	theme	cementitious	1189:1200	arg1	systems					1202:1208	cementitious systems	1189:1208	cementitious systems	1189:1208	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	6	24	theme	higher	1034:1039	arg1	degree					1041:1046	a 15% higher degree	1028:1046	a 15% higher degree of hydration at 28 days	1028:1070	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	1	25	theme	shrimp	179:184	arg1	tonnes					169:174	Every year ~ 6-8 million tonnes	144:174	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes	144:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	0	26	theme	chitin	10:15	arg1	nanofibers					17:26	chitin nanofibers	10:26	chitin nanofibers	10:26	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	6	27	theme	silicate	1001:1008	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	5	28	theme	Elastic	770:776	arg1	modulus					778:784	Elastic modulus	770:784	Elastic modulus	770:784	Elastic modulus increased by up to 91% and 43% with ChNC and ChNF.					
36446851	7	29	theme	structural	1146:1155	arg1	nanofibers					1157:1166	powerful structural nanofibers	1137:1166	powerful structural nanofibers	1137:1166	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	0	30	theme	nanocrystals	32:43	arg1	Impact					0:5	Impact	0:5	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.	0:142	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	4	31	theme	greatest	698:705	arg1	strength					725:732	the greatest improved flexural strength	694:732	the greatest improved flexural strength	694:732	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	1	32	theme	crab	187:190	arg1	tonnes					169:174	Every year ~ 6-8 million tonnes	144:174	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes	144:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	2	33	theme	chitin	351:356	arg1	ChNC					372:375	ChNC	372:375	ChNC	372:375	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	2	33	theme	chitin	351:356	arg1	nanocrystals					358:369	chitin nanocrystals	351:369	chitin nanocrystals (ChNC)	351:376	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	0	34	theme	late-age	114:121	arg1	hydration					123:131	late-age hydration	114:131	late-age hydration	114:131	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	35	from	shells	63:68	arg1	nanocrystals					32:43	nanocrystals	32:43	nanocrystals	32:43	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	35	from	shells	63:68	arg1	Impact					0:5	Impact	0:5	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.	0:142	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	35	from	shells	63:68	arg1	nanofibers					17:26	chitin nanofibers	10:26	chitin nanofibers	10:26	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	6	36	theme	magnetic	857:864	arg1	NMR					877:879	NMR	877:879	NMR	877:879	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	6	36	theme	magnetic	857:864	arg1	resonance					866:874	Solid-state nuclear magnetic resonance	837:874	Solid-state nuclear magnetic resonance (NMR)	837:880	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	2	37	theme	chitin	417:422	arg1	ChNF					436:439	ChNF	436:439	ChNF	436:439	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	2	37	theme	chitin	417:422	arg1	nanofibers					424:433	chitin nanofibers	417:433	chitin nanofibers (ChNF)	417:440	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	0	38	theme	mortar	136:141	arg1	hydration					123:131	late-age hydration	114:131	late-age hydration	114:131	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	38	theme	mortar	136:141	arg1	properties					84:93	mechanical properties	73:93	mechanical properties	73:93	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	38	theme	mortar	136:141	arg1	time					104:107	setting time	96:107	setting time	96:107	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	0	39	theme	shrimp	56:61	arg1	shells					63:68	waste shrimp shells	50:68	waste shrimp shells	50:68	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	4	40	theme	flexural	716:723	arg1	strength					725:732	the greatest improved flexural strength	694:732	the greatest improved flexural strength	694:732	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	6	41	theme	higher	960:965	arg1	degree					967:972	a 41% higher degree	954:972	a 41% higher degree of polymerization	954:990	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	4	42	theme	improved	707:714	arg1	strength					725:732	the greatest improved flexural strength	694:732	the greatest improved flexural strength	694:732	ChNF (0.05 wt%) with a larger aspect ratio than ChNC resulted in the greatest improved flexural strength and fracture energy by 24% and 28%.					
36446851	7	43	theme	viable	1111:1116	arg1	source					1126:1131	a viable biomass source	1109:1131	a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems	1109:1208	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	3	44	theme	final	531:535	arg1	time					545:548	the final setting time	527:548	the final setting time	527:548	ChNF (0.075 wt%) and ChNC (0.05 wt%) retarded the final setting time by 50 and 30 min, likely through cement dispersion by electrostatic repulsion.					
36446851	2	45	theme	chitin	290:295	arg1	content					297:303	the chitin content	286:303	the chitin content of shrimp shell waste	286:325	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	2	45	theme	chitin	290:295	arg1	additives					459:467	additives	459:467	additives for mortar	459:478	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	6	46	dep	showed	882:887	arg1	enhanced					905:912	enhanced	905:912	showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days	882:1070	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	3	47	theme	setting	537:543	arg1	time					545:548	the final setting time	527:548	the final setting time	527:548	ChNF (0.075 wt%) and ChNC (0.05 wt%) retarded the final setting time by 50 and 30 min, likely through cement dispersion by electrostatic repulsion.					
36446851	1	48	theme	lobster	197:203	arg1	wastes					211:216	lobster shell wastes	197:216	lobster shell wastes	197:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	5	49	dep	%	807:807	arg1	to					802:803	to	802:803	to	802:803	Elastic modulus increased by up to 91% and 43% with ChNC and ChNF.					
36446851	7	50	theme	biomass	1118:1124	arg1	source					1126:1131	a viable biomass source	1109:1131	a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems	1109:1208	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	1	51	theme	shell	205:209	arg1	wastes					211:216	lobster shell wastes	197:216	lobster shell wastes	197:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36446851	0	52	theme	waste	50:54	arg1	shells					63:68	waste shrimp shells	50:68	waste shrimp shells	50:68	Impact of chitin nanofibers and nanocrystals from waste shrimp shells on mechanical properties, setting time, and late-age hydration of mortar.					
36446851	7	53	theme	powerful	1137:1144	arg1	nanofibers					1157:1166	powerful structural nanofibers	1137:1166	powerful structural nanofibers	1137:1166	Based on the findings, chitin seems a viable biomass source for powerful structural nanofibers and nanocrystals for cementitious systems to divert seafood waste from landfills or the sea.					
36446851	6	54	theme	chain	1010:1014	arg1	length					1016:1021	9% more silicate chain length	993:1021	9% more silicate chain length	993:1021	Solid-state nuclear magnetic resonance (NMR) showed ChNF (0.05 wt%) enhanced calcium-silicate-hydrate structure with a 41% higher degree of polymerization, 9% more silicate chain length, and a 15% higher degree of hydration at 28 days.					
36446851	2	55	theme	waste	321:325	arg1	content					297:303	the chitin content	286:303	the chitin content of shrimp shell waste	286:325	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	2	55	theme	waste	321:325	arg1	additives					459:467	additives	459:467	additives for mortar	459:478	In this study, the chitin content of shrimp shell waste was oxidized to produce chitin nanocrystals (ChNC) and mechanically fibrillated to obtain chitin nanofibers (ChNF) and evaluated as additives for mortar.					
36446851	1	56	theme	wastes	211:216	arg1	tonnes					169:174	Every year ~ 6-8 million tonnes	144:174	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes	144:216	Every year ~ 6-8 million tonnes of shrimp, crab, and lobster shell wastes are generated, requiring costly disposal procedures.					
36898460	0	0	theme	fire	94:97	arg1	safety					99:104	enhanced fire safety	85:104	enhanced fire safety	85:104	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	3	1	theme	heat	596:599	arg1	rate					609:612	total heat release rate	590:612	total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS	590:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	1	theme	heat	596:599	arg1	THR					615:617	THR	615:617	THR	615:617	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	2	2	theme	boronic	531:537	arg1	APBA					545:548	APBA	545:548	APBA	545:548	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	2	theme	boronic	531:537	arg1	acid					539:542	3-aminophenyl boronic acid	517:542	3-aminophenyl boronic acid (APBA)	517:549	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	6	3	theme	tri-element	1277:1287	arg1	hybrid					1289:1294	a chitosan-based N/B/P tri-element hybrid	1254:1294	a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites	1254:1380	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	4	4	theme	condensed	873:881	arg1	phase					883:887	the condensed phase	869:887	the condensed phase	869:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	1	5	theme	lactic	253:258	arg1	poly					248:251	poly	248:251	poly(lactic acid) (PLA)	248:270	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	1	5	theme	lactic	253:258	arg1	acid					260:263	lactic acid	253:263	lactic acid	253:263	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	0	6	theme	enhanced	85:92	arg1	safety					99:104	enhanced fire safety	85:104	enhanced fire safety	85:104	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	2	7	theme	3-aminophenyl	517:529	arg1	APBA					545:548	APBA	545:548	APBA	545:548	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	7	theme	3-aminophenyl	517:529	arg1	acid					539:542	3-aminophenyl boronic acid	517:542	3-aminophenyl boronic acid (APBA)	517:549	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	8	theme	PLA	333:335	arg1	properties					319:328	mechanical properties	308:328	mechanical properties of PLA	308:335	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	8	theme	PLA	333:335	arg1	resistance					293:302	the fire resistance	284:302	the fire resistance	284:302	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	6	9	theme	biocomposites	1368:1380	arg1	performance					1323:1333	fire safety performance	1311:1333	fire safety performance	1311:1333	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	6	9	theme	biocomposites	1368:1380	arg1	properties					1350:1359	mechanical properties	1339:1359	mechanical properties	1339:1359	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	5	10	theme	@	1134:1134	arg1	CS					1135:1136	PLA/APBA@PA@CS	1123:1136	PLA/APBA@PA@CS	1123:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	6	11	theme	safety	1316:1321	arg1	performance					1323:1333	fire safety performance	1311:1333	fire safety performance	1311:1333	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	5	12	from	break	1078:1082	arg1	strength					1054:1061	the tensile strength	1042:1061	the tensile strength	1042:1061	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	12	from	break	1078:1082	arg1	Meanwhile					1031:1039	Meanwhile	1031:1039	Meanwhile	1031:1039	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	12	from	break	1078:1082	arg1	strength					1092:1099	impact strength	1085:1099	impact strength	1085:1099	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	12	from	break	1078:1082	arg1	crystallinity					1106:1118	crystallinity	1106:1118	crystallinity of PLA/APBA@PA@CS	1106:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	12	from	break	1078:1082	arg1	elongation					1064:1073	elongation	1064:1073	elongation at break	1064:1082	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	0	13	contain	carrying	40:47	arg2	elements					55:62	N/P/B elements	49:62	N/P/B elements for polylactide	49:78	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	0	13	contain	carrying	40:47	arg1	hybrid					33:38	biobased chitosan hybrid	15:38	biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties	15:130	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	3	14	contain	containing	637:646	arg1	composite					627:635	PLA composite	623:635	PLA composite containing 3 wt% APBA@PA@CS	623:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	14	contain	containing	637:646	arg2	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	4	15	from	phosphorus	845:854	arg1	phase					883:887	the condensed phase	869:887	the condensed phase	869:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	15	from	phosphorus	845:854	arg1	rich					837:840	rich	837:840	rich	837:840	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	6	16	theme	N/B/P	1271:1275	arg1	hybrid					1289:1294	a chitosan-based N/B/P tri-element hybrid	1254:1294	a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites	1254:1380	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	5	17	theme	@	1131:1131	arg1	CS					1135:1136	PLA/APBA@PA@CS	1123:1136	PLA/APBA@PA@CS	1123:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	6	18	dep	performance	1323:1333	arg1	the					1307:1309	the	1307:1309	the	1307:1309	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	4	19	from	gases	916:920	arg1	phase					933:937	the gas phase	925:937	the gas phase	925:937	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	2	20	theme	additive	382:389	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	20	theme	additive	382:389	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	0	21	theme	mechanical	110:119	arg1	properties					121:130	mechanical properties	110:130	mechanical properties	110:130	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	3	22	theme	release	601:607	arg1	rate					609:612	total heat release rate	590:612	total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS	590:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	22	theme	release	601:607	arg1	THR					615:617	THR	615:617	THR	615:617	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	4	23	theme	rich	837:840	arg1	layer					831:835	a high-quality char layer	811:835	a high-quality char layer rich in phosphorus and boron in the condensed phase	811:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	24	theme	heat	965:968	arg1	exchange					953:960	the exchange	949:960	the exchange of heat and O2	949:975	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	0	25	theme	biobased	15:22	arg1	hybrid					33:38	biobased chitosan hybrid	15:38	biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties	15:130	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	4	26	theme	high-quality	813:824	arg1	layer					831:835	a high-quality char layer	811:835	a high-quality char layer rich in phosphorus and boron in the condensed phase	811:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	27	theme	retardant	1013:1021	arg1	effect					1023:1028	a synergistic flame retardant effect	993:1028	a synergistic flame retardant effect	993:1028	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	5	28	theme	CS	1135:1136	arg1	strength					1054:1061	the tensile strength	1042:1061	the tensile strength	1042:1061	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	28	theme	CS	1135:1136	arg1	Meanwhile					1031:1039	Meanwhile	1031:1039	Meanwhile	1031:1039	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	28	theme	CS	1135:1136	arg1	strength					1092:1099	impact strength	1085:1099	impact strength	1085:1099	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	28	theme	CS	1135:1136	arg1	crystallinity					1106:1118	crystallinity	1106:1118	crystallinity of PLA/APBA@PA@CS	1106:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	5	28	theme	CS	1135:1136	arg1	elongation					1064:1073	elongation	1064:1073	elongation at break	1064:1082	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	2	29	theme	flame	366:370	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	29	theme	flame	366:370	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	3	30	theme	PLA	623:625	arg1	composite					627:635	PLA composite	623:635	PLA composite containing 3 wt% APBA@PA@CS	623:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	6	31	theme	PLA	1364:1366	arg1	biocomposites					1368:1380	PLA biocomposites	1364:1380	PLA biocomposites	1364:1380	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	2	32	theme	fire	288:291	arg1	resistance					293:302	the fire resistance	284:302	the fire resistance	284:302	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	6	33	theme	chitosan-based	1256:1269	arg1	hybrid					1289:1294	a chitosan-based N/B/P tri-element hybrid	1254:1294	a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites	1254:1380	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	1	34	theme	low	198:200	arg1	crystallinity					202:214	low crystallinity	198:214	low crystallinity	198:214	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	3	35	theme	composite	627:635	arg1	THR					615:617	THR	615:617	THR	615:617	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	35	theme	composite	627:635	arg1	rate					574:577	The peak heat release rate	552:577	The peak heat release rate (pHRR)	552:584	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	35	theme	composite	627:635	arg1	pHRR					580:583	pHRR	580:583	pHRR	580:583	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	35	theme	composite	627:635	arg1	rate					609:612	total heat release rate	590:612	total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS	590:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	2	36	theme	phytic	495:500	arg1	PA					508:509	PA	508:509	PA	508:509	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	36	theme	phytic	495:500	arg1	acid					502:505	phytic acid	495:505	phytic acid (PA)	495:510	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	4	37	theme	gas	929:931	arg1	phase					933:937	the gas phase	925:937	the gas phase	925:937	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	2	38	theme	PA	397:398	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	38	theme	PA	397:398	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	39	theme	@	399:399	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	39	theme	@	399:399	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	4	40	from	boron	860:864	arg1	phase					883:887	the condensed phase	869:887	the condensed phase	869:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	40	from	boron	860:864	arg1	rich					837:840	rich	837:840	rich	837:840	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	41	theme	@	772:772	arg1	CS					776:777	APBA@PA@CS	768:777	APBA@PA@CS	768:777	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	42	theme	peak	556:559	arg1	rate					574:577	The peak heat release rate	552:577	The peak heat release rate (pHRR)	552:584	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	42	theme	peak	556:559	arg1	pHRR					580:583	pHRR	580:583	pHRR	580:583	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	5	43	theme	PLA/APBA	1123:1130	arg1	CS					1135:1136	PLA/APBA@PA@CS	1123:1136	PLA/APBA@PA@CS	1123:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	2	44	theme	@	396:396	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	44	theme	@	396:396	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	0	45	theme	N/P/B	49:53	arg1	elements					55:62	N/P/B elements	49:62	N/P/B elements for polylactide	49:78	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	5	46	theme	PA	1132:1133	arg1	CS					1135:1136	PLA/APBA@PA@CS	1123:1136	PLA/APBA@PA@CS	1123:1136	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	4	47	theme	CS	776:777	arg1	presence					756:763	The presence	752:763	The presence of APBA@PA@CS	752:777	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	48	theme	heat	561:564	arg1	rate					574:577	The peak heat release rate	552:577	The peak heat release rate (pHRR)	552:584	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	48	theme	heat	561:564	arg1	pHRR					580:583	pHRR	580:583	pHRR	580:583	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	2	49	theme	core-shell	355:364	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	49	theme	core-shell	355:364	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	50	theme	APBA	392:395	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	50	theme	APBA	392:395	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	4	51	theme	layer	831:835	arg1	formation					798:806	the formation	794:806	the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase	794:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	52	theme	%	652:652	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	4	53	theme	@	775:775	arg1	CS					776:777	APBA@PA@CS	768:777	APBA@PA@CS	768:777	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	54	theme	@	658:658	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	2	55	theme	interactions	461:472	arg1	self-assembly					433:445	the self-assembly	429:445	the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA)	429:549	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	3	56	theme	APBA	654:657	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	6	57	theme	mechanical	1339:1348	arg1	properties					1350:1359	mechanical properties	1339:1359	mechanical properties	1339:1359	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	4	58	from	rich	837:840	arg1	boron					860:864	boron	860:864	boron	860:864	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	58	from	rich	837:840	arg1	phosphorus					845:854	phosphorus	845:854	phosphorus	845:854	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	59	theme	PA	773:774	arg1	CS					776:777	APBA@PA@CS	768:777	APBA@PA@CS	768:777	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	60	theme	flame	1007:1011	arg1	effect					1023:1028	a synergistic flame retardant effect	993:1028	a synergistic flame retardant effect	993:1028	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	4	61	theme	char	826:829	arg1	layer					831:835	a high-quality char layer	811:835	a high-quality char layer rich in phosphorus and boron in the condensed phase	811:887	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	62	theme	3 wt	648:651	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	4	63	theme	APBA	768:771	arg1	CS					776:777	APBA@PA@CS	768:777	APBA@PA@CS	768:777	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	6	64	theme	feasible	1226:1233	arg1	route					1235:1239	a feasible route	1224:1239	a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites	1224:1380	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	4	65	theme	synergistic	995:1005	arg1	effect					1023:1028	a synergistic flame retardant effect	993:1028	a synergistic flame retardant effect	993:1028	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	1	66	theme	inherent	137:144	arg1	brittleness					181:191	brittleness	181:191	brittleness	181:191	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	1	66	theme	inherent	137:144	arg1	shortcomings					146:157	The inherent shortcomings	133:157	The inherent shortcomings such as flammability, brittleness, and low crystallinity	133:214	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	1	66	theme	inherent	137:144	arg1	flammability					167:178	flammability	167:178	flammability	167:178	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	1	66	theme	inherent	137:144	arg1	crystallinity					202:214	low crystallinity	198:214	low crystallinity	198:214	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	4	67	theme	non-flammable	902:914	arg1	gases					916:920	non-flammable gases	902:920	non-flammable gases in the gas phase	902:937	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	3	68	theme	@	661:661	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	69	theme	release	566:572	arg1	rate					574:577	The peak heat release rate	552:577	The peak heat release rate (pHRR)	552:584	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	69	theme	release	566:572	arg1	pHRR					580:583	pHRR	580:583	pHRR	580:583	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	4	70	theme	O2	974:975	arg1	exchange					953:960	the exchange	949:960	the exchange of heat and O2	949:975	The presence of APBA@PA@CS contributed to the formation of a high-quality char layer rich in phosphorus and boron in the condensed phase and released non-flammable gases in the gas phase to hinder the exchange of heat and O2, thereby having a synergistic flame retardant effect.					
36898460	2	71	theme	mechanical	308:317	arg1	properties					319:328	mechanical properties	308:328	mechanical properties of PLA	308:335	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	72	theme	interionic	450:459	arg1	interactions					461:472	interionic interactions	450:472	interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA)	450:549	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	1	73	theme	broad	226:230	arg1	applications					232:243	the broad applications	222:243	the broad applications of poly(lactic acid) (PLA)	222:270	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	6	74	theme	fire	1311:1314	arg1	performance					1323:1333	fire safety performance	1311:1333	fire safety performance	1311:1333	This study provides a feasible route to construct a chitosan-based N/B/P tri-element hybrid to improve the fire safety performance and mechanical properties of PLA biocomposites.					
36898460	2	75	theme	chitosan-based	340:353	arg1	retardant					372:380	a chitosan-based core-shell flame retardant additive	338:389	a chitosan-based core-shell flame retardant additive (APBA@PA@CS)	338:402	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	2	75	theme	chitosan-based	340:353	arg1	CS					400:401	APBA@PA@CS	392:401	APBA@PA@CS	392:401	To improve the fire resistance and mechanical properties of PLA, a chitosan-based core-shell flame retardant additive (APBA@PA@CS) was prepared for PLA via the self-assembly of interionic interactions among chitosan (CS), phytic acid (PA), and 3-aminophenyl boronic acid (APBA).					
36898460	5	76	theme	impact	1085:1090	arg1	strength					1092:1099	impact strength	1085:1099	impact strength	1085:1099	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	1	77	theme	poly	248:251	arg1	applications					232:243	the broad applications	222:243	the broad applications of poly(lactic acid) (PLA)	222:270	The inherent shortcomings such as flammability, brittleness, and low crystallinity limit the broad applications of poly(lactic acid) (PLA).					
36898460	3	78	theme	total	590:594	arg1	rate					609:612	total heat release rate	590:612	total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS	590:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	3	78	theme	total	590:594	arg1	THR					615:617	THR	615:617	THR	615:617	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
36898460	0	79	theme	chitosan	24:31	arg1	hybrid					33:38	biobased chitosan hybrid	15:38	biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties	15:130	Self-assembled biobased chitosan hybrid carrying N/P/B elements for polylactide with enhanced fire safety and mechanical properties.					
36898460	5	80	theme	tensile	1046:1052	arg1	strength					1054:1061	the tensile strength	1042:1061	the tensile strength	1042:1061	Meanwhile, the tensile strength, elongation at break, impact strength, and crystallinity of PLA/APBA@PA@CS were increased by 3.7 %, 17.4 %, 5.3 %, and 55.2 %, respectively.					
36898460	3	81	theme	PA	659:660	arg1	CS					662:663	3 wt% APBA@PA@CS	648:663	3 wt% APBA@PA@CS	648:663	The peak heat release rate (pHRR) and total heat release rate (THR) of PLA composite containing 3 wt% APBA@PA@CS decreased from 460.1 kW/m2 and 75.8 MJ/m2 to 419.0 kW/m2 and 53.1 MJ/m2, respectively.					
35994941	6	0	theme	h-1	889:891	arg1	rate					876:879	a feed flow rate	864:879	a feed flow rate of 5 ml h-1	864:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	0	theme	h-1	889:891	arg1	tip					926:928	syringe tip	918:928	syringe tip to collector distance at 30 cm	918:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	0	theme	h-1	889:891	arg1	time					975:978	spinning time	966:978	spinning time of 10 min	966:988	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	0	theme	h-1	889:891	arg1	pressure					898:905	air pressure	894:905	air pressure of 3 bars	894:915	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	1	from	cm	958:959	arg1	distance					943:950	collector distance	933:950	collector distance at 30 cm	933:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	2	theme	ml	886:887	arg1	h-1					889:891	5 ml h-1	884:891	5 ml h-1	884:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	5	3	theme	spinnable	588:596	arg1	precursor					606:614	an easily spinnable polymer precursor	578:614	an easily spinnable polymer precursor	578:614	However, incorporating an easily spinnable polymer precursor, such as polyacrylonitrile (PAN), to pectin effectively enabled the production of fibers from the SBS process.					
35994941	7	4	dep	v/v	1052:1054	arg1	i.e.					1039:1042	i.e.	1039:1042	i.e.	1039:1042	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	7	5	from	PAN	991:993	arg1	DMSO					998:1001	DMSO solvent	998:1009	DMSO solvent	998:1009	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	6	6	theme	5	884:884	arg1	ml					886:887	ml	886:887	ml	886:887	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	7	7	theme	volume	1024:1029	arg1	ratios					1031:1036	different volume ratios	1014:1036	different volume ratios (i.e. 35%-55% v/v)	1014:1055	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	7	7	theme	volume	1024:1029	arg1	v/v					1052:1054	35%-55% v/v	1044:1054	35%-55% v/v	1044:1054	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	5	8	theme	polymer	598:604	arg1	precursor					606:614	an easily spinnable polymer precursor	578:614	an easily spinnable polymer precursor	578:614	However, incorporating an easily spinnable polymer precursor, such as polyacrylonitrile (PAN), to pectin effectively enabled the production of fibers from the SBS process.					
35994941	2	9	theme	biopolymer	269:278	arg1	fibers					280:285	biopolymer fibers	269:285	biopolymer fibers	269:285	However, the fabrication of biopolymer fibers is not as straightforward as synthetic polymers.					
35994941	1	10	theme	essential	92:100	arg1	prerequisite					102:113	An essential prerequisite	89:113	An essential prerequisite for successful solution blow spinning (SBS)	89:157	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	10	theme	essential	92:100	arg1	presence					166:173	the presence	162:173	the presence of effective molecular entanglements of polymers in the solution	162:238	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	6	11	theme	collector	933:941	arg1	distance					943:950	collector distance	933:950	collector distance at 30 cm	933:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	5	12	theme	SBS	714:716	arg1	process					718:724	the SBS process	710:724	the SBS process	710:724	However, incorporating an easily spinnable polymer precursor, such as polyacrylonitrile (PAN), to pectin effectively enabled the production of fibers from the SBS process.					
35994941	9	13	theme	composite	1300:1308	arg1	fibers					1319:1324	the composite SBS-spun fibers	1296:1324	the composite SBS-spun fibers obtained	1296:1333	Furthermore, the composite SBS-spun fibers obtained suggest that its formation is concentration-dependent.					
35994941	3	14	theme	SBS	472:474	arg1	method					487:492	the SBS production method	468:492	the SBS production method	468:492	Particularly for biopolymers such as pectin, molecular entanglements are essential but insufficient for successful spinning through the SBS production method.					
35994941	8	15	theme	high	1131:1134	arg1	PAN					1162:1164	PAN	1162:1164	PAN	1162:1164	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	8	15	theme	high	1131:1134	arg1	polymer					1153:1159	a high molecular weight polymer	1129:1159	a high molecular weight polymer	1129:1159	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	9	16	theme	SBS-spun	1310:1317	arg1	fibers					1319:1324	the composite SBS-spun fibers	1296:1324	the composite SBS-spun fibers obtained	1296:1333	Furthermore, the composite SBS-spun fibers obtained suggest that its formation is concentration-dependent.					
35994941	6	17	theme	flow	871:874	arg1	rate					876:879	a feed flow rate	864:879	a feed flow rate of 5 ml h-1	864:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	18	theme	syringe	918:924	arg1	tip					926:928	syringe tip	918:928	syringe tip to collector distance at 30 cm	918:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	8	19	theme	solution	1218:1225	arg1	viscoelasticity					1195:1209	the viscoelasticity	1191:1209	the viscoelasticity of the solution	1191:1225	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	3	20	theme	successful	440:449	arg1	spinning					451:458	successful spinning	440:458	successful spinning through the SBS production method	440:492	Particularly for biopolymers such as pectin, molecular entanglements are essential but insufficient for successful spinning through the SBS production method.					
35994941	6	21	theme	feed	866:869	arg1	rate					876:879	a feed flow rate	864:879	a feed flow rate of 5 ml h-1	864:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	5	22	dep	such	617:620	arg1	as					622:623	as	622:623	as	622:623	However, incorporating an easily spinnable polymer precursor, such as polyacrylonitrile (PAN), to pectin effectively enabled the production of fibers from the SBS process.					
35994941	7	23	theme	solvent	1003:1009	arg1	DMSO					998:1001	DMSO solvent	998:1009	DMSO solvent	998:1009	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	6	24	theme	pectin	757:762	arg1	nanofibers					764:773	PAN-assisted pectin nanofibers	744:773	PAN-assisted pectin nanofibers	744:773	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	8	25	theme	molecular	1136:1144	arg1	PAN					1162:1164	PAN	1162:1164	PAN	1162:1164	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	8	25	theme	molecular	1136:1144	arg1	polymer					1153:1159	a high molecular weight polymer	1129:1159	a high molecular weight polymer	1129:1159	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	6	26	theme	min	986:988	arg1	rate					876:879	a feed flow rate	864:879	a feed flow rate of 5 ml h-1	864:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	26	theme	min	986:988	arg1	tip					926:928	syringe tip	918:928	syringe tip to collector distance at 30 cm	918:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	26	theme	min	986:988	arg1	time					975:978	spinning time	966:978	spinning time of 10 min	966:988	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	26	theme	min	986:988	arg1	pressure					898:905	air pressure	894:905	air pressure of 3 bars	894:915	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	4	27	theme	complex	539:545	arg1	nature					547:552	the biopolymer's complex nature	522:552	the biopolymer's complex nature	522:552	Such a challenge is due to the biopolymer's complex nature.					
35994941	6	28	theme	PAN-assisted	744:755	arg1	nanofibers					764:773	PAN-assisted pectin nanofibers	744:773	PAN-assisted pectin nanofibers	744:773	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	8	29	theme	weight	1146:1151	arg1	PAN					1162:1164	PAN	1162:1164	PAN	1162:1164	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	8	29	theme	weight	1146:1151	arg1	polymer					1153:1159	a high molecular weight polymer	1129:1159	a high molecular weight polymer	1129:1159	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	0	30	theme	mango	15:19	arg1	Preparation					0:10	Preparation	0:10	Preparation of mango	0:19	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	2	31	theme	fibers	280:285	arg1	straightforward					297:311	straightforward	297:311	straightforward	297:311	However, the fabrication of biopolymer fibers is not as straightforward as synthetic polymers.					
35994941	2	31	theme	fibers	280:285	arg1	fabrication					254:264	the fabrication	250:264	the fabrication of biopolymer fibers	250:285	However, the fabrication of biopolymer fibers is not as straightforward as synthetic polymers.					
35994941	1	32	theme	effective	178:186	arg1	entanglements					198:210	effective molecular entanglements	178:210	effective molecular entanglements of polymers	178:222	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	6	33	theme	bars	912:915	arg1	rate					876:879	a feed flow rate	864:879	a feed flow rate of 5 ml h-1	864:891	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	33	theme	bars	912:915	arg1	tip					926:928	syringe tip	918:928	syringe tip to collector distance at 30 cm	918:959	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	33	theme	bars	912:915	arg1	time					975:978	spinning time	966:978	spinning time of 10 min	966:988	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	33	theme	bars	912:915	arg1	pressure					898:905	air pressure	894:905	air pressure of 3 bars	894:915	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	5	34	theme	fibers	698:703	arg1	production					684:693	the production	680:693	the production of fibers	680:703	However, incorporating an easily spinnable polymer precursor, such as polyacrylonitrile (PAN), to pectin effectively enabled the production of fibers from the SBS process.					
35994941	8	35	theme	SBS	1270:1272	arg1	process					1274:1280	its successful SBS process	1255:1280	its successful SBS process	1255:1280	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	1	36	theme	molecular	188:196	arg1	entanglements					198:210	effective molecular entanglements	178:210	effective molecular entanglements of polymers	178:222	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	0	37	theme	pectin-based	32:43	arg1	nanofibers					45:54	pectin-based nanofibers	32:54	pectin-based nanofibers	32:54	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	7	38	theme	%	1050:1050	arg1	ratios					1031:1036	different volume ratios	1014:1036	different volume ratios (i.e. 35%-55% v/v)	1014:1055	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	7	38	theme	%	1050:1050	arg1	v/v					1052:1054	35%-55% v/v	1044:1054	35%-55% v/v	1044:1054	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	1	39	attach	presence	166:173	arg2	entanglements					198:210	effective molecular entanglements	178:210	effective molecular entanglements of polymers	178:222	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	39	attach	presence	166:173	arg1	solution					231:238	the solution	227:238	the solution	227:238	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	8	40	theme	successful	1259:1268	arg1	process					1274:1280	its successful SBS process	1255:1280	its successful SBS process	1255:1280	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	1	41	theme	entanglements	198:210	arg1	prerequisite					102:113	An essential prerequisite	89:113	An essential prerequisite for successful solution blow spinning (SBS)	89:157	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	41	theme	entanglements	198:210	arg1	presence					166:173	the presence	162:173	the presence of effective molecular entanglements of polymers in the solution	162:238	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	3	42	theme	molecular	381:389	arg1	entanglements					391:403	molecular entanglements	381:403	molecular entanglements	381:403	Particularly for biopolymers such as pectin, molecular entanglements are essential but insufficient for successful spinning through the SBS production method.					
35994941	6	43	dep	477.09 ± 6.60	841:853	arg1	to					838:839	to	838:839	to	838:839	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	0	44	theme	blow	68:71	arg1	SBS					83:85	SBS	83:85	SBS	83:85	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	0	44	theme	blow	68:71	arg1	spinning					73:80	solution blow spinning	59:80	solution blow spinning (SBS)	59:86	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	7	45	theme	%	1046:1046	arg1	ratios					1031:1036	different volume ratios	1014:1036	different volume ratios (i.e. 35%-55% v/v)	1014:1055	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	7	45	theme	%	1046:1046	arg1	v/v					1052:1054	35%-55% v/v	1044:1054	35%-55% v/v	1044:1054	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	3	46	theme	production	476:485	arg1	method					487:492	the SBS production method	468:492	the SBS production method	468:492	Particularly for biopolymers such as pectin, molecular entanglements are essential but insufficient for successful spinning through the SBS production method.					
35994941	7	47	theme	different	1014:1022	arg1	ratios					1031:1036	different volume ratios	1014:1036	different volume ratios (i.e. 35%-55% v/v)	1014:1055	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	7	47	theme	different	1014:1022	arg1	v/v					1052:1054	35%-55% v/v	1044:1054	35%-55% v/v	1044:1054	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
35994941	2	48	theme	synthetic	316:324	arg1	polymers					326:333	synthetic polymers	316:333	synthetic polymers	316:333	However, the fabrication of biopolymer fibers is not as straightforward as synthetic polymers.					
35994941	6	49	theme	air	894:896	arg1	pressure					898:905	air pressure	894:905	air pressure of 3 bars	894:915	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	6	50	theme	average	793:799	arg1	diameters					801:809	average diameters	793:809	average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm	793:856	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	1	51	theme	successful	119:128	arg1	spinning					144:151	successful solution blow spinning	119:151	successful solution blow spinning (SBS)	119:157	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	51	theme	successful	119:128	arg1	SBS					154:156	SBS	154:156	SBS	154:156	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	8	52	theme	polymer	1153:1159	arg1	addition					1117:1124	The addition	1113:1124	The addition of a high molecular weight polymer, PAN, to pectin	1113:1175	The addition of a high molecular weight polymer, PAN, to pectin also improved the viscoelasticity of the solution, eventually contributing to its successful SBS process.					
35994941	1	53	theme	solution	130:137	arg1	spinning					144:151	successful solution blow spinning	119:151	successful solution blow spinning (SBS)	119:157	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	53	theme	solution	130:137	arg1	SBS					154:156	SBS	154:156	SBS	154:156	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	54	theme	polymers	215:222	arg1	entanglements					198:210	effective molecular entanglements	178:210	effective molecular entanglements of polymers	178:222	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	6	55	theme	spinning	966:973	arg1	time					975:978	spinning time	966:978	spinning time of 10 min	966:988	In this process, PAN-assisted pectin nanofibers are produced with average diameters ranging from 410.75 ± 3.73 to 477.09 ± 6.60 nm using a feed flow rate of 5 ml h-1, air pressure of 3 bars, syringe tip to collector distance at 30 cm, and spinning time of 10 min.					
35994941	1	56	from	presence	166:173	arg1	solution					231:238	the solution	227:238	the solution	227:238	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	57	theme	blow	139:142	arg1	spinning					144:151	successful solution blow spinning	119:151	successful solution blow spinning (SBS)	119:157	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	1	57	theme	blow	139:142	arg1	SBS					154:156	SBS	154:156	SBS	154:156	An essential prerequisite for successful solution blow spinning (SBS) is the presence of effective molecular entanglements of polymers in the solution.					
35994941	0	58	theme	solution	59:66	arg1	SBS					83:85	SBS	83:85	SBS	83:85	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	0	58	theme	solution	59:66	arg1	spinning					73:80	solution blow spinning	59:80	solution blow spinning (SBS)	59:86	Preparation of mango peel-waste pectin-based nanofibers by solution blow spinning (SBS).					
35994941	7	59	from	ratios	1031:1036	arg1	PAN					991:993	PAN	991:993	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v)	991:1055	PAN in DMSO solvent at different volume ratios (i.e. 35%-55% v/v) was critical in assisting pectin to produce nanofibers.					
36106571	0	0	theme	cell	70:73	arg1	mechanics					80:88	plant cell wall mechanics	64:88	plant cell wall mechanics	64:88	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.					
36106571	3	1	theme	pectin	319:324	arg1	gels					326:329	pectin gels	319:329	pectin gels	319:329	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	3	2	dep	transport	359:367	arg1	the					349:351	the	349:351	the	349:351	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	1	3	theme	dehydration	135:145	arg1	cycles					125:130	multiple cycles	116:130	multiple cycles of dehydration and rehydration	116:161	Plant cell walls undergo multiple cycles of dehydration and rehydration during their life.					
36106571	6	4	theme	pectin	864:869	arg1	gels					871:874	pectin gels	864:874	pectin gels	864:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	0	5	theme	plant	64:68	arg1	mechanics					80:88	plant cell wall mechanics	64:88	plant cell wall mechanics	64:88	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.					
36106571	4	6	theme	gels	493:496	arg1	mechanics					470:478	the mechanics	466:478	the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration	466:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	5	7	theme	egg-box	636:642	arg1	feature					671:677	a characteristic feature	654:677	a characteristic feature of the microstructure of low methoxy pectin-Ca gels	654:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	5	7	theme	egg-box	636:642	arg1	bundles					644:650	egg-box bundles	636:650	egg-box bundles	636:650	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	6	8	theme	small	793:797	arg1	scattering					813:822	small angle neutron scattering	793:822	small angle neutron scattering	793:822	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	9	9	theme	Microstructural	1242:1256	arg1	changes					1258:1264	Microstructural changes	1242:1264	Microstructural changes due to the aggregation of egg-box bundles and single chains	1242:1324	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	4	10	theme	rehydration	559:569	arg1	extents					521:527	different extents	511:527	different extents of dehydration and subsequent rehydration	511:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	5	11	theme	low	704:706	arg1	gels					726:729	low methoxy pectin-Ca gels	704:729	low methoxy pectin-Ca gels	704:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	4	12	theme	pectin-Ca	483:491	arg1	gels					493:496	pectin-Ca gels	483:496	pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration	483:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	6	13	theme	dehydration-rehydration	947:969	arg1	cycles					971:976	dehydration-rehydration cycles	947:976	dehydration-rehydration cycles	947:976	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	3	14	theme	water	353:357	arg1	transport					359:367	water transport	353:367	water transport	353:367	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	4	15	theme	microstructure	448:461	arg1	contributions					427:439	the contributions	423:439	the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration	423:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	9	16	from	changes	1258:1264	arg1	configurations					1366:1379	the water configurations	1356:1379	the water configurations	1356:1379	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	9	17	theme	water	1360:1364	arg1	configurations					1366:1379	the water configurations	1356:1379	the water configurations	1356:1379	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	5	18	theme	pectin-Ca	716:724	arg1	gels					726:729	low methoxy pectin-Ca gels	704:729	low methoxy pectin-Ca gels	704:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	9	19	theme	single	1312:1317	arg1	chains					1319:1324	single chains	1312:1324	single chains	1312:1324	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	5	20	theme	gel	608:610	arg1	composition					612:622	a pectin gel composition	599:622	a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels	599:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	5	21	theme	pectin	601:606	arg1	composition					612:622	a pectin gel composition	599:622	a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels	599:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	2	22	theme	walls	258:262	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	22	theme	walls	258:262	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	9	23	theme	chains	1319:1324	arg1	aggregation					1277:1287	the aggregation	1273:1287	the aggregation of egg-box bundles and single chains	1273:1324	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	1	24	theme	rehydration	151:161	arg1	cycles					125:130	multiple cycles	116:130	multiple cycles of dehydration and rehydration	116:161	Plant cell walls undergo multiple cycles of dehydration and rehydration during their life.					
36106571	5	25	theme	gels	726:729	arg1	microstructure					686:699	the microstructure	682:699	the microstructure of low methoxy pectin-Ca gels	682:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	9	26	theme	bundles	1300:1306	arg1	aggregation					1277:1287	the aggregation	1273:1287	the aggregation of egg-box bundles and single chains	1273:1324	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	2	27	theme	cell	253:256	arg1	walls					258:262	plant cell walls	247:262	plant cell walls	247:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	6	28	used	used	879:882	arg2	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	6	28	used	used	879:882	arg2	gels					871:874	pectin gels	864:874	pectin gels	864:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	3	29	theme	gels	326:329	arg1	behavior					307:314	the dehydration-rehydration behavior	279:314	the dehydration-rehydration behavior of pectin gels	279:329	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	7	30	theme	yield	1074:1078	arg1	strain					1080:1085	yield strain	1074:1085	yield strain	1074:1085	As the extent of dehydration increases, the reswelling ability, strain-stiffening behavior and yield strain decrease.					
36106571	6	31	theme	LAOS	767:770	arg1	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	0	32	theme	Pectin	0:5	arg1	self-assembly					7:19	Pectin self-assembly	0:19	Pectin self-assembly	0:19	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.					
36106571	4	33	theme	dehydration	532:542	arg1	extents					521:527	different extents	511:527	different extents of dehydration and subsequent rehydration	511:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	9	34	from	changes	1345:1351	arg1	configurations					1366:1379	the water configurations	1356:1379	the water configurations	1356:1379	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	9	35	theme	associated	1334:1343	arg1	changes					1345:1351	the associated changes	1330:1351	the associated changes in the water configurations	1330:1379	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	6	36	theme	shear	760:764	arg1	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	4	37	theme	subsequent	548:557	arg1	rehydration					559:569	subsequent rehydration	548:569	subsequent rehydration	548:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	6	38	theme	NIR	843:845	arg1	spectroscopy					848:859	near infrared (NIR) spectroscopy	828:859	near infrared (NIR) spectroscopy	828:859	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	1	39	theme	Plant	91:95	arg1	walls					102:106	Plant cell walls	91:106	Plant cell walls	91:106	Plant cell walls undergo multiple cycles of dehydration and rehydration during their life.					
36106571	8	40	theme	faster	1133:1138	arg1	rates					1140:1144	faster rates	1133:1144	faster rates of dehydration	1133:1159	These effects are more prominent at faster rates of dehydration and are not completely reversible upon rehydration to the initial undried state.					
36106571	6	41	theme	microstructural	916:930	arg1	changes					932:938	the mechanical and microstructural changes	897:938	the mechanical and microstructural changes during dehydration-rehydration cycles	897:976	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	5	42	theme	microstructure	686:699	arg1	feature					671:677	a characteristic feature	654:677	a characteristic feature of the microstructure of low methoxy pectin-Ca gels	654:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	5	42	theme	microstructure	686:699	arg1	bundles					644:650	egg-box bundles	636:650	egg-box bundles	636:650	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	8	43	theme	undried	1227:1233	arg1	state					1235:1239	the initial undried state	1215:1239	the initial undried state	1215:1239	These effects are more prominent at faster rates of dehydration and are not completely reversible upon rehydration to the initial undried state.					
36106571	7	44	theme	strain-stiffening	1043:1059	arg1	behavior					1061:1068	strain-stiffening behavior	1043:1068	strain-stiffening behavior	1043:1068	As the extent of dehydration increases, the reswelling ability, strain-stiffening behavior and yield strain decrease.					
36106571	5	45	theme	methoxy	708:714	arg1	gels					726:729	low methoxy pectin-Ca gels	704:729	low methoxy pectin-Ca gels	704:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	6	46	theme	oscillatory	748:758	arg1	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	2	47	link	crosslinked	190:200	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	47	link	crosslinked	190:200	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	3	48	theme	plant	386:390	arg1	cells					392:396	plant cells	386:396	plant cells	386:396	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	6	49	theme	mechanical	901:910	arg1	changes					932:938	the mechanical and microstructural changes	897:938	the mechanical and microstructural changes during dehydration-rehydration cycles	897:976	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	7	50	theme	reswelling	1023:1032	arg1	ability					1034:1040	the reswelling ability	1019:1040	the reswelling ability	1019:1040	As the extent of dehydration increases, the reswelling ability, strain-stiffening behavior and yield strain decrease.					
36106571	6	51	theme	near	828:831	arg1	spectroscopy					848:859	near infrared (NIR) spectroscopy	828:859	near infrared (NIR) spectroscopy	828:859	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	8	52	from	rates	1140:1144	arg1	prominent					1120:1128	prominent	1120:1128	prominent	1120:1128	These effects are more prominent at faster rates of dehydration and are not completely reversible upon rehydration to the initial undried state.					
36106571	6	53	theme	amplitude	738:746	arg1	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	1	54	theme	cell	97:100	arg1	walls					102:106	Plant cell walls	91:106	Plant cell walls	91:106	Plant cell walls undergo multiple cycles of dehydration and rehydration during their life.					
36106571	3	55	theme	cells	392:396	arg1	mechanics					373:381	mechanics	373:381	mechanics	373:381	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	3	55	theme	cells	392:396	arg1	transport					359:367	water transport	353:367	water transport	353:367	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	2	56	theme	low	202:204	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	56	theme	low	202:204	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	57	theme	methoxy	206:212	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	57	theme	methoxy	206:212	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	6	58	theme	Large	732:736	arg1	rheology					773:780	Large amplitude oscillatory shear (LAOS) rheology	732:780	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels	732:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	6	59	theme	infrared	833:840	arg1	spectroscopy					848:859	near infrared (NIR) spectroscopy	828:859	near infrared (NIR) spectroscopy	828:859	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	4	60	theme	different	511:519	arg1	extents					521:527	different extents	511:527	different extents of dehydration and subsequent rehydration	511:569	In this work, we report the contributions of the microstructure to the mechanics of pectin-Ca gels subjected to different extents of dehydration and subsequent rehydration.					
36106571	5	61	theme	characteristic	656:669	arg1	feature					671:677	a characteristic feature	654:677	a characteristic feature of the microstructure of low methoxy pectin-Ca gels	654:729	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	5	61	theme	characteristic	656:669	arg1	bundles					644:650	egg-box bundles	636:650	egg-box bundles	636:650	This is investigated using a pectin gel composition that forms 'egg-box bundles', a characteristic feature of the microstructure of low methoxy pectin-Ca gels.					
36106571	2	62	theme	crosslinked	190:200	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	62	theme	crosslinked	190:200	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	63	theme	plant	247:251	arg1	walls					258:262	plant cell walls	247:262	plant cell walls	247:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	8	64	theme	dehydration	1149:1159	arg1	rates					1140:1144	faster rates	1133:1144	faster rates of dehydration	1133:1159	These effects are more prominent at faster rates of dehydration and are not completely reversible upon rehydration to the initial undried state.					
36106571	3	65	theme	dehydration-rehydration	283:305	arg1	behavior					307:314	the dehydration-rehydration behavior	279:314	the dehydration-rehydration behavior of pectin gels	279:329	Understanding the dehydration-rehydration behavior of pectin gels may shed light on the water transport and mechanics of plant cells.					
36106571	2	66	theme	Calcium	182:188	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	66	theme	Calcium	182:188	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	7	67	theme	dehydration	996:1006	arg1	extent					986:991	the extent	982:991	the extent of dehydration	982:1006	As the extent of dehydration increases, the reswelling ability, strain-stiffening behavior and yield strain decrease.					
36106571	1	68	theme	multiple	116:123	arg1	cycles					125:130	multiple cycles	116:130	multiple cycles of dehydration and rehydration	116:161	Plant cell walls undergo multiple cycles of dehydration and rehydration during their life.					
36106571	6	69	theme	angle	799:803	arg1	scattering					813:822	small angle neutron scattering	793:822	small angle neutron scattering	793:822	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	0	70	dep	self-assembly	7:19	arg1	insights					50:57	insights	50:57	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.	0:89	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.					
36106571	6	71	theme	neutron	805:811	arg1	scattering					813:822	small angle neutron scattering	793:822	small angle neutron scattering	793:822	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	9	72	theme	due	1266:1268	arg1	changes					1258:1264	Microstructural changes	1242:1264	Microstructural changes due to the aggregation of egg-box bundles and single chains	1242:1324	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	6	73	from	rheology	773:780	arg1	gels					871:874	pectin gels	864:874	pectin gels	864:874	Large amplitude oscillatory shear (LAOS) rheology along with small angle neutron scattering and near infrared (NIR) spectroscopy on pectin gels is used to elucidate the mechanical and microstructural changes during dehydration-rehydration cycles.					
36106571	9	74	theme	irreversible	1395:1406	arg1	changes					1408:1414	these irreversible changes	1389:1414	these irreversible changes	1389:1414	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	8	75	theme	initial	1219:1225	arg1	state					1235:1239	the initial undried state	1215:1239	the initial undried state	1215:1239	These effects are more prominent at faster rates of dehydration and are not completely reversible upon rehydration to the initial undried state.					
36106571	9	76	theme	egg-box	1292:1298	arg1	bundles					1300:1306	egg-box bundles	1292:1306	egg-box bundles	1292:1306	Microstructural changes due to the aggregation of egg-box bundles and single chains and the associated changes in the water configurations lead to these irreversible changes.					
36106571	2	77	theme	major	226:230	arg1	constituent					232:242	a major constituent	224:242	a major constituent of plant cell walls	224:262	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	2	77	theme	major	226:230	arg1	pectin					214:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin	182:219	Calcium crosslinked low methoxy pectin is a major constituent of plant cell walls.					
36106571	0	78	theme	wall	75:78	arg1	mechanics					80:88	plant cell wall mechanics	64:88	plant cell wall mechanics	64:88	Pectin self-assembly and its disruption by water: insights into plant cell wall mechanics.					
36681725	0	0	theme	Eucalyptus	79:88	arg1	Sm					103:104	Eucalyptus tereticornis Sm	79:104	Eucalyptus tereticornis Sm	79:104	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	0	theme	Eucalyptus	79:88	arg1	Isolation					0:8	Isolation	0:8	Isolation	0:8	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	5	1	theme	pulping	535:541	arg1	process					543:549	Kraft pulping process	529:549	Kraft pulping process followed by alkaline and bleaching pre-treatments	529:599	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	1	2	theme	explosion	148:156	arg1	method					158:163	steam explosion method	142:163	steam explosion method	142:163	and Casuarina equisetifolia L., by steam explosion method.					
36681725	6	3	theme	Electron	655:662	arg1	SEM					676:678	SEM	676:678	SEM	676:678	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	3	theme	Electron	655:662	arg1	Microscopy					664:673	Scanning Electron Microscopy	646:673	Scanning Electron Microscopy (SEM)	646:679	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	11	4	theme	nanocellulose	1560:1572	arg1	stability					1547:1555	the higher thermal stability	1528:1555	the higher thermal stability of nanocellulose	1528:1572	During TG analysis the untreated fibres started to degrade earlier than the nanocellulose which indicated the higher thermal stability of nanocellulose.					
36681725	9	5	theme	elemental	1198:1206	arg1	purity					1208:1213	The elemental purity	1194:1213	The elemental purity of nanocellulose	1194:1230	The elemental purity of nanocellulose was confirmed with EDAX detector.					
36681725	6	6	theme	Scanning	646:653	arg1	SEM					676:678	SEM	676:678	SEM	676:678	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	6	theme	Scanning	646:653	arg1	Microscopy					664:673	Scanning Electron Microscopy	646:673	Scanning Electron Microscopy (SEM)	646:679	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	10	7	theme	significant	1367:1377	arg1	conversion					1379:1388	the significant conversion	1363:1388	the significant conversion of cellulose I to cellulose II	1363:1419	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	3	8	theme	wood	354:357	arg1	pulp					359:362	wood pulp	354:362	wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm	354:421	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	3	9	attach	isolated	340:347	arg1	pulp					359:362	wood pulp	354:362	wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm	354:421	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	3	9	attach	isolated	340:347	arg2	nanocellulose					322:334	nanocellulose	322:334	nanocellulose	322:334	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	10	10	theme	cellulose	1393:1401	arg1	conversion					1379:1388	the significant conversion	1363:1388	the significant conversion of cellulose I to cellulose II	1363:1419	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	6	11	theme	Thermogravimetric	798:814	arg1	TGA					826:828	TGA	826:828	TGA	826:828	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	11	theme	Thermogravimetric	798:814	arg1	Analysis					816:823	Thermogravimetric Analysis	798:823	Thermogravimetric Analysis (TGA)	798:829	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	2	12	theme	structural	285:294	arg1	hierarchy					296:304	structural hierarchy	285:304	its complex chemical structure as well as structural hierarchy	243:304	Extraction of nanocellulose is challenging, especially from hardwoods due to its complex chemical structure as well as structural hierarchy.					
36681725	6	13	theme	Force	729:733	arg1	AFM					747:749	AFM	747:749	AFM	747:749	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	13	theme	Force	729:733	arg1	Microscopy					735:744	Atomic Force Microscopy	722:744	Atomic Force Microscopy (AFM)	722:750	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	0	14	theme	tereticornis	90:101	arg1	Sm					103:104	Eucalyptus tereticornis Sm	79:104	Eucalyptus tereticornis Sm	79:104	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	14	theme	tereticornis	90:101	arg1	Isolation					0:8	Isolation	0:8	Isolation	0:8	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	15	from	hardwoods	62:70	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	15	from	hardwoods	62:70	arg1	Sm					103:104	Eucalyptus tereticornis Sm	79:104	Eucalyptus tereticornis Sm	79:104	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	15	from	hardwoods	62:70	arg1	Isolation					0:8	Isolation	0:8	Isolation	0:8	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	15	from	hardwoods	62:70	arg1	viz.					73:76	viz.	73:76	viz.	73:76	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	10	16	theme	cellulose	1316:1324	arg1	enrichment					1290:1299	the enrichment	1286:1299	the enrichment of crystalline cellulose in nanocellulose	1286:1341	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	5	17	theme	cellulose	488:496	arg1	pulp					503:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	4	18	theme	explosion	464:472	arg1	process					474:480	steam explosion process	458:480	steam explosion process	458:480	and Casuarina equisetifolia L. by steam explosion process.					
36681725	7	19	theme	average	949:955	arg1	diameter					957:964	average diameter	949:964	average diameter of 27.801 nm	949:977	Nanocellulose obtained from both species showed non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images.					
36681725	5	20	theme	wood	498:501	arg1	pulp					503:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	8	21	theme	peaks	1163:1167	arg1	cellulose					1138:1146	cellulose	1138:1146	cellulose	1138:1146	FTIR spectra of nanocellulose showed prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin.					
36681725	8	21	theme	peaks	1163:1167	arg1	absence					1152:1158	absence	1152:1158	absence	1152:1158	FTIR spectra of nanocellulose showed prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin.					
36681725	6	22	theme	FTIR	783:786	arg1	Spectra					789:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	1	23	dep	L.	135:136	arg1	method					158:163	steam explosion method	142:163	steam explosion method	142:163	and Casuarina equisetifolia L., by steam explosion method.					
36681725	13	24	theme	nanofibres	1803:1812	arg1	production					1779:1788	industrial level production	1762:1788	industrial level production of cellulose nanofibres	1762:1812	This successful method can be replicated for industrial level production of cellulose nanofibres.					
36681725	3	25	theme	hardwood	371:378	arg1	species					380:386	two hardwood species	367:386	two hardwood species	367:386	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	3	25	theme	hardwood	371:378	arg1	tereticornis					407:418	tereticornis	407:418	tereticornis	407:418	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	13	26	theme	successful	1722:1731	arg1	method					1733:1738	This successful method	1717:1738	This successful method	1717:1738	This successful method can be replicated for industrial level production of cellulose nanofibres.					
36681725	5	27	theme	bleaching	576:584	arg1	pre-treatments					586:599	alkaline and bleaching pre-treatments	563:599	alkaline and bleaching pre-treatments	563:599	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	8	28	theme	nanocellulose	1084:1096	arg1	spectra					1073:1079	FTIR spectra	1068:1079	FTIR spectra of nanocellulose	1068:1096	FTIR spectra of nanocellulose showed prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin.					
36681725	3	29	theme	species	380:386	arg1	pulp					359:362	wood pulp	354:362	wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm	354:421	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	3	30	dep	tereticornis	407:418	arg1	Sm					420:421	Sm	420:421	Eucalyptus tereticornis Sm	396:421	In this study, nanocellulose was isolated from wood pulp of two hardwood species, namely Eucalyptus tereticornis Sm.					
36681725	11	31	theme	untreated	1445:1453	arg1	fibres					1455:1460	the untreated fibres	1441:1460	the untreated fibres	1441:1460	During TG analysis the untreated fibres started to degrade earlier than the nanocellulose which indicated the higher thermal stability of nanocellulose.					
36681725	10	32	theme	XRD	1266:1268	arg1	analysis					1270:1277	XRD analysis	1266:1277	XRD analysis	1266:1277	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	12	33	theme	aspect	1631:1636	arg1	ratio					1638:1642	high aspect ratio	1626:1642	high aspect ratio	1626:1642	Highly entangled network like structure along with high aspect ratio make the nanofibres a versatile material for reinforcing the composites.					
36681725	7	34	theme	AFM	1056:1058	arg1	images					1060:1065	AFM images	1056:1065	AFM images	1056:1065	Nanocellulose obtained from both species showed non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images.					
36681725	6	35	theme	Infrared	773:780	arg1	Spectra					789:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	12	36	theme	entangled	1582:1590	arg1	network					1592:1598	Highly entangled network	1575:1598	Highly entangled network like structure along with high aspect ratio	1575:1642	Highly entangled network like structure along with high aspect ratio make the nanofibres a versatile material for reinforcing the composites.					
36681725	13	37	theme	cellulose	1793:1801	arg1	nanofibres					1803:1812	cellulose nanofibres	1793:1812	cellulose nanofibres	1793:1812	This successful method can be replicated for industrial level production of cellulose nanofibres.					
36681725	6	38	theme	Isolated	602:609	arg1	nanocellulose					611:623	Isolated nanocellulose	602:623	Isolated nanocellulose	602:623	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	11	39	theme	thermal	1539:1545	arg1	stability					1547:1555	the higher thermal stability	1528:1555	the higher thermal stability of nanocellulose	1528:1572	During TG analysis the untreated fibres started to degrade earlier than the nanocellulose which indicated the higher thermal stability of nanocellulose.					
36681725	2	40	theme	nanocellulose	180:192	arg1	Extraction					166:175	Extraction	166:175	Extraction of nanocellulose	166:192	Extraction of nanocellulose is challenging, especially from hardwoods due to its complex chemical structure as well as structural hierarchy.					
36681725	6	41	theme	Transmission	682:693	arg1	Microscopy					704:713	Transmission Electron Microscopy	682:713	Transmission Electron Microscopy (TEM)	682:719	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	41	theme	Transmission	682:693	arg1	TEM					716:718	TEM	716:718	TEM	716:718	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	42	theme	Electron	695:702	arg1	Microscopy					704:713	Transmission Electron Microscopy	682:713	Transmission Electron Microscopy (TEM)	682:719	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	42	theme	Electron	695:702	arg1	TEM					716:718	TEM	716:718	TEM	716:718	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	13	43	theme	industrial	1762:1771	arg1	production					1779:1788	industrial level production	1762:1788	industrial level production of cellulose nanofibres	1762:1812	This successful method can be replicated for industrial level production of cellulose nanofibres.					
36681725	7	44	with	difference	933:942	arg1	diameter					957:964	average diameter	949:964	average diameter of 27.801 nm	949:977	Nanocellulose obtained from both species showed non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images.					
36681725	5	45	theme	Pure	483:486	arg1	pulp					503:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp	483:506	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	0	46	theme	nanocellulose	34:46	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	46	theme	nanocellulose	34:46	arg1	Sm					103:104	Eucalyptus tereticornis Sm	79:104	Eucalyptus tereticornis Sm	79:104	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	46	theme	nanocellulose	34:46	arg1	Isolation					0:8	Isolation	0:8	Isolation	0:8	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	0	46	theme	nanocellulose	34:46	arg1	viz.					73:76	viz.	73:76	viz.	73:76	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	13	47	theme	level	1773:1777	arg1	production					1779:1788	industrial level production	1762:1788	industrial level production of cellulose nanofibres	1762:1812	This successful method can be replicated for industrial level production of cellulose nanofibres.					
36681725	4	48	theme	steam	458:462	arg1	process					474:480	steam explosion process	458:480	steam explosion process	458:480	and Casuarina equisetifolia L. by steam explosion process.					
36681725	2	49	theme	due	236:238	arg1	hardwoods					226:234	hardwoods	226:234	hardwoods due to its complex chemical structure as well as structural hierarchy	226:304	Extraction of nanocellulose is challenging, especially from hardwoods due to its complex chemical structure as well as structural hierarchy.					
36681725	6	50	theme	Transformed	761:771	arg1	Spectra					789:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	10	51	theme	crystalline	1304:1314	arg1	cellulose					1316:1324	crystalline cellulose	1304:1324	crystalline cellulose	1304:1324	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	9	52	theme	EDAX	1251:1254	arg1	detector					1256:1263	EDAX detector	1251:1263	EDAX detector	1251:1263	The elemental purity of nanocellulose was confirmed with EDAX detector.					
36681725	6	53	theme	Fourier	753:759	arg1	Spectra					789:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Fourier Transformed Infrared (FTIR) Spectra	753:795	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	0	54	theme	selected	53:60	arg1	hardwoods					62:70	selected hardwoods	53:70	selected hardwoods	53:70	Isolation and characterization of nanocellulose from selected hardwoods, viz., Eucalyptus tereticornis Sm.					
36681725	12	55	theme	high	1626:1629	arg1	ratio					1638:1642	high aspect ratio	1626:1642	high aspect ratio	1626:1642	Highly entangled network like structure along with high aspect ratio make the nanofibres a versatile material for reinforcing the composites.					
36681725	8	56	theme	FTIR	1068:1071	arg1	spectra					1073:1079	FTIR spectra	1068:1079	FTIR spectra of nanocellulose	1068:1096	FTIR spectra of nanocellulose showed prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin.					
36681725	10	57	from	enrichment	1290:1299	arg1	nanocellulose					1329:1341	nanocellulose	1329:1341	nanocellulose	1329:1341	XRD analysis showed the enrichment of crystalline cellulose in nanocellulose, and also confirmed the significant conversion of cellulose I to cellulose II.					
36681725	6	58	dep	Microscopy	664:673	arg1	studies					860:866	studies	860:866	studies	860:866	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	59	theme	X-ray	836:840	arg1	XRD					855:857	XRD	855:857	XRD	855:857	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	59	theme	X-ray	836:840	arg1	diffraction					842:852	X-ray diffraction	836:852	X-ray diffraction (XRD)	836:858	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	9	60	theme	nanocellulose	1218:1230	arg1	purity					1208:1213	The elemental purity	1194:1213	The elemental purity of nanocellulose	1194:1230	The elemental purity of nanocellulose was confirmed with EDAX detector.					
36681725	7	61	theme	non-significant	917:931	arg1	difference					933:942	non-significant difference	917:942	non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images	917:1065	Nanocellulose obtained from both species showed non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images.					
36681725	5	62	theme	alkaline	563:570	arg1	pre-treatments					586:599	alkaline and bleaching pre-treatments	563:599	alkaline and bleaching pre-treatments	563:599	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	7	63	theme	27.801 nm	969:977	arg1	diameter					957:964	average diameter	949:964	average diameter of 27.801 nm	949:977	Nanocellulose obtained from both species showed non-significant difference with average diameter of 27.801 nm for eucalyptus and 28.690 nm for casuarina, which was confirmed from TEM and AFM images.					
36681725	4	64	dep	Casuarina	428:436	arg1	L.					452:453	and Casuarina equisetifolia L.	424:453	L.	452:453	and Casuarina equisetifolia L. by steam explosion process.					
36681725	4	64	dep	Casuarina	428:436	arg1	process					474:480	steam explosion process	458:480	steam explosion process	458:480	and Casuarina equisetifolia L. by steam explosion process.					
36681725	8	65	theme	prominent	1105:1113	arg1	peaks					1115:1119	prominent peaks	1105:1119	prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin	1105:1191	FTIR spectra of nanocellulose showed prominent peaks corresponding to cellulose and absence of peaks corresponding to lignin.					
36681725	2	66	theme	chemical	255:262	arg1	structure					264:272	its complex chemical structure	243:272	its complex chemical structure as well as structural hierarchy	243:304	Extraction of nanocellulose is challenging, especially from hardwoods due to its complex chemical structure as well as structural hierarchy.					
36681725	12	67	theme	versatile	1666:1674	arg1	material					1676:1683	a versatile material	1664:1683	a versatile material for reinforcing the composites	1664:1714	Highly entangled network like structure along with high aspect ratio make the nanofibres a versatile material for reinforcing the composites.					
36681725	2	68	theme	complex	247:253	arg1	structure					264:272	its complex chemical structure	243:272	its complex chemical structure as well as structural hierarchy	243:304	Extraction of nanocellulose is challenging, especially from hardwoods due to its complex chemical structure as well as structural hierarchy.					
36681725	11	69	theme	higher	1532:1537	arg1	stability					1547:1555	the higher thermal stability	1528:1555	the higher thermal stability of nanocellulose	1528:1572	During TG analysis the untreated fibres started to degrade earlier than the nanocellulose which indicated the higher thermal stability of nanocellulose.					
36681725	5	70	theme	Kraft	529:533	arg1	process					543:549	Kraft pulping process	529:549	Kraft pulping process followed by alkaline and bleaching pre-treatments	529:599	Pure cellulose wood pulp was obtained through Kraft pulping process followed by alkaline and bleaching pre-treatments.					
36681725	1	71	theme	steam	142:146	arg1	method					158:163	steam explosion method	142:163	steam explosion method	142:163	and Casuarina equisetifolia L., by steam explosion method.					
36681725	6	72	theme	Atomic	722:727	arg1	AFM					747:749	AFM	747:749	AFM	747:749	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	6	72	theme	Atomic	722:727	arg1	Microscopy					735:744	Atomic Force Microscopy	722:744	Atomic Force Microscopy (AFM)	722:750	Isolated nanocellulose was characterized by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Fourier Transformed Infrared (FTIR) Spectra, Thermogravimetric Analysis (TGA), and X-ray diffraction (XRD) studies.					
36681725	11	73	theme	TG	1429:1430	arg1	analysis					1432:1439	TG analysis	1429:1439	TG analysis	1429:1439	During TG analysis the untreated fibres started to degrade earlier than the nanocellulose which indicated the higher thermal stability of nanocellulose.					
36044886	9	0	theme	hydrogel	2052:2059	arg1	designs					2061:2067	experimental hydrogel designs	2039:2067	experimental hydrogel designs	2039:2067	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	8	1	theme	consistent	1746:1755	arg1	upregulation					1757:1768	consistent upregulation	1746:1768	consistent upregulation of osteocalcin gene expression	1746:1799	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	2	2	theme	Various	314:320	arg1	groups					322:327	Various groups	314:327	Various groups	314:327	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	1	3	theme	regenerative	227:238	arg1	medicine					240:247	regenerative medicine	227:247	regenerative medicine	227:247	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	1	4	used	used	141:144	arg2	hydrogels					121:129	Hyaluronic acid (HA) hydrogels	100:129	Hyaluronic acid (HA) hydrogels	100:129	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	8	5	theme	gene	1785:1788	arg1	expression					1790:1799	osteocalcin gene expression	1773:1799	osteocalcin gene expression	1773:1799	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	3	6	dep	altering	729:736	arg1	e.g.					724:727	e.g.	724:727	e.g.	724:727	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	9	7	theme	hydrogel	1862:1869	arg1	parameters					1871:1880	hydrogel parameters	1862:1880	hydrogel parameters	1862:1880	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	5	8	theme	thiol-ene	981:989	arg1	chemistry					997:1005	thiol-ene click chemistry	981:1005	thiol-ene click chemistry with a crosslinker	981:1024	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	3	9	dep	weight	748:753	arg1	investigate					779:789	investigate	779:789	to investigate cell response to stiffness	776:816	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	8	10	theme	mesenchymal	1652:1662	arg1	cells					1669:1673	rat mesenchymal stem cells	1648:1673	rat mesenchymal stem cells	1648:1673	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	3	11	theme	cell	791:794	arg1	response					796:803	cell response	791:803	cell response to stiffness	791:816	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	4	12	theme	cell	834:837	arg1	responses					839:847	cell responses	834:847	cell responses	834:847	Therefore, if cell responses differ, it may be possible that more than one variable caused the changes in observed responses.					
36044886	6	13	theme	Independent	1208:1218	arg1	control					1220:1226	Independent control	1208:1226	Independent control	1208:1226	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	8	14	theme	cells	1669:1673	arg1	response					1636:1643	The response	1632:1643	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness	1632:1731	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	7	15	theme	technical	1609:1617	arg1	achievement					1619:1629	a key technical achievement	1603:1629	a key technical achievement	1603:1629	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	7	15	theme	technical	1609:1617	arg1	constant					1593:1600	constant	1593:1600	constant	1593:1600	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	9	16	from	variables	2026:2034	arg1	designs					2061:2067	experimental hydrogel designs	2039:2067	experimental hydrogel designs	2039:2067	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	3	17	theme	hydrogel	576:583	arg1	variable					611:618	a 'manipulated variable'	596:619	a 'manipulated variable'	596:619	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	17	theme	hydrogel	576:583	arg1	parameter					585:593	one hydrogel parameter	572:593	one hydrogel parameter (a 'manipulated variable')	572:620	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	8	18	theme	varying	1678:1684	arg1	weight					1696:1701	varying molecular weight	1678:1701	varying molecular weight	1678:1701	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	2	19	theme	vitroandin	438:447	arg1	vivoto					449:454	vitroandin vivoto	438:454	vitroandin vivoto	438:454	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	3	20	theme	manipulated	599:609	arg1	variable					611:618	a 'manipulated variable'	596:619	a 'manipulated variable'	596:619	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	20	theme	manipulated	599:609	arg1	parameter					585:593	one hydrogel parameter	572:593	one hydrogel parameter (a 'manipulated variable')	572:620	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	9	21	theme	hydrogel	1935:1942	arg1	polymers					1944:1951	alternative hydrogel polymers	1923:1951	alternative hydrogel polymers	1923:1951	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	3	22	theme	molecular	738:746	arg1	weight					748:753	molecular weight	738:753	molecular weight	738:753	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	0	23	theme	acid	84:87	arg1	control					12:18	Independent control	0:18	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid	0:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	2	24	theme	material	472:479	arg1	characteristics					493:507	desired material performance characteristics	464:507	desired material performance characteristics	464:507	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	25	dep	investigated	334:345	arg1	achieve					456:462	achieve	456:462	achieve desired material performance characteristics	456:507	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	26	theme	hydrogel	361:368	arg1	parameters					370:379	hydrogel parameters	361:379	hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)	361:434	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	27	dep	weight	397:402	arg1	e.g.					382:385	e.g.	382:385	e.g.	382:385	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	0	28	theme	Independent	0:10	arg1	control					12:18	Independent control	0:18	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid	0:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	2	29	theme	molecular	387:395	arg1	concentration					405:417	concentration	405:417	concentration	405:417	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	29	theme	molecular	387:395	arg1	weight					397:402	molecular weight	387:402	molecular weight	387:402	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	29	theme	molecular	387:395	arg1	etc					431:433	etc	431:433	etc	431:433	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	29	theme	molecular	387:395	arg1	stiffness					420:428	stiffness	420:428	stiffness	420:428	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	6	30	theme	molecular	1359:1367	arg1	weights					1369:1375	different HA hydrogel molecular weights	1337:1375	different HA hydrogel molecular weights	1337:1375	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	1	31	theme	Hyaluronic	100:109	arg1	HA					117:118	HA	117:118	HA	117:118	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	1	31	theme	Hyaluronic	100:109	arg1	acid					111:114	Hyaluronic acid	100:114	Hyaluronic acid (HA) hydrogels	100:129	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	9	32	theme	culture	1974:1980	arg1	medium					1982:1987	cell culture medium	1969:1987	cell culture medium	1969:1987	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	0	33	theme	weight	33:38	arg1	control					12:18	Independent control	0:18	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid	0:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	6	34	theme	HA	1347:1348	arg1	weights					1369:1375	different HA hydrogel molecular weights	1337:1375	different HA hydrogel molecular weights	1337:1375	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	2	35	from	impact	351:356	arg1	vivoto					449:454	vitroandin vivoto	438:454	vitroandin vivoto	438:454	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	6	36	theme	constant	1314:1321	arg1	stiffness					1323:1331	an effectively constant stiffness	1299:1331	an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations	1299:1402	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	0	37	theme	concentration	41:53	arg1	control					12:18	Independent control	0:18	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid	0:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	5	38	theme	material	1061:1068	arg1	changes					1082:1088	material performance changes	1061:1088	material performance changes	1061:1088	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	7	39	theme	molecular	1468:1476	arg1	weight					1478:1483	the molecular weight	1464:1483	the molecular weight (76-1550 kDa)	1464:1497	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	7	39	theme	molecular	1468:1476	arg1	kDa					1494:1496	76-1550 kDa	1486:1496	76-1550 kDa	1486:1496	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	1	40	theme	tissue	204:209	arg1	engineering					211:221	tissue engineering	204:221	tissue engineering	204:221	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	9	41	theme	experimental	2039:2050	arg1	designs					2061:2067	experimental hydrogel designs	2039:2067	experimental hydrogel designs	2039:2067	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	5	42	theme	material	1113:1120	arg1	properties					1122:1131	multiple material properties	1104:1131	multiple material properties	1104:1131	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	3	43	theme	given	635:639	arg1	variable					680:687	a 'controlled variable'	666:688	a 'controlled variable'	666:688	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	43	theme	given	635:639	arg1	characteristic					650:663	a given hydrogel characteristic	633:663	a given hydrogel characteristic (a 'controlled variable')	633:689	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	8	44	theme	osteocalcin	1773:1783	arg1	expression					1790:1799	osteocalcin gene expression	1773:1799	osteocalcin gene expression	1773:1799	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	7	45	theme	Specific	1405:1412	arg1	formulations					1414:1425	Specific formulations	1405:1425	Specific formulations	1405:1425	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	3	46	theme	controlled	669:678	arg1	variable					680:687	a 'controlled variable'	666:688	a 'controlled variable'	666:688	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	46	theme	controlled	669:678	arg1	characteristic					650:663	a given hydrogel characteristic	633:663	a given hydrogel characteristic (a 'controlled variable')	633:689	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	8	47	theme	expression	1790:1799	arg1	upregulation					1757:1768	consistent upregulation	1746:1768	consistent upregulation of osteocalcin gene expression	1746:1799	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	1	48	theme	polymer	282:288	arg1	versatility					263:273	the versatility	259:273	the versatility of the polymer	259:288	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	9	49	theme	independent	1839:1849	arg1	control					1851:1857	independent control	1839:1857	independent control of hydrogel parameters	1839:1880	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	1	50	theme	applications	165:176	arg1	multitude					152:160	a multitude	150:160	a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer	150:288	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	1	50	theme	applications	165:176	arg1	nature					306:311	its tunable nature	294:311	its tunable nature	294:311	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	5	51	theme	single	1181:1186	arg1	variable					1188:1195	a single variable	1179:1195	a single variable	1179:1195	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	9	52	theme	parameters	1871:1880	arg1	control					1851:1857	independent control	1839:1857	independent control of hydrogel parameters	1839:1880	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	5	53	theme	click	991:995	arg1	chemistry					997:1005	thiol-ene click chemistry	981:1005	thiol-ene click chemistry with a crosslinker	981:1024	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	1	54	theme	acid	111:114	arg1	hydrogels					121:129	Hyaluronic acid (HA) hydrogels	100:129	Hyaluronic acid (HA) hydrogels	100:129	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	5	55	theme	current	953:959	arg1	study					961:965	the current study	949:965	the current study	949:965	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	8	56	theme	rat	1648:1650	arg1	cells					1669:1673	rat mesenchymal stem cells	1648:1673	rat mesenchymal stem cells	1648:1673	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	5	57	with	chemistry	997:1005	arg1	crosslinker					1014:1024	a crosslinker	1012:1024	a crosslinker	1012:1024	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	0	58	theme	stiffness	60:68	arg1	control					12:18	Independent control	0:18	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid	0:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	8	59	theme	stem	1664:1667	arg1	cells					1669:1673	rat mesenchymal stem cells	1648:1673	rat mesenchymal stem cells	1648:1673	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	7	60	theme	%	1516:1516	arg1	%					1520:1520	2%-10%	1515:1520	2%-10%	1515:1520	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	7	60	theme	%	1516:1516	arg1	concentration					1500:1512	concentration	1500:1512	concentration (2%-10%)	1500:1521	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	0	61	theme	hyaluronic	73:82	arg1	acid					84:87	hyaluronic acid	73:87	hyaluronic acid	73:87	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	1	62	theme	tunable	298:304	arg1	nature					306:311	its tunable nature	294:311	its tunable nature	294:311	Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature.					
36044886	7	63	theme	key	1605:1607	arg1	achievement					1619:1629	a key technical achievement	1603:1629	a key technical achievement	1603:1629	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	7	63	theme	key	1605:1607	arg1	constant					1593:1600	constant	1593:1600	constant	1593:1600	Specific formulations were thereby identified that enabled the molecular weight (76-1550 kDa), concentration (2%-10%), or stiffness (∼1-350 kPa) to be varied while the other two were held constant, a key technical achievement.					
36044886	9	64	theme	alternative	1923:1933	arg1	polymers					1944:1951	alternative hydrogel polymers	1923:1951	alternative hydrogel polymers	1923:1951	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	3	65	from	limitation	512:521	arg1	literature					530:539	the literature	526:539	the literature	526:539	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	66	dep	time	718:721	arg1	altering					729:736	altering	729:736	altering molecular weight and/or concentration to investigate cell response to stiffness	729:816	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	8	67	theme	molecular	1686:1694	arg1	weight					1696:1701	varying molecular weight	1678:1701	varying molecular weight	1678:1701	The response of rat mesenchymal stem cells to varying molecular weight, concentration, and stiffness demonstrated consistent upregulation of osteocalcin gene expression.					
36044886	2	68	theme	performance	481:491	arg1	characteristics					493:507	desired material performance characteristics	464:507	desired material performance characteristics	464:507	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	6	69	theme	crosslinker	1276:1286	arg1	concentration					1259:1271	the concentration	1255:1271	the concentration of crosslinker	1255:1286	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	2	70	theme	desired	464:470	arg1	characteristics					493:507	desired material performance characteristics	464:507	desired material performance characteristics	464:507	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	9	71	theme	cell	1954:1957	arg1	types					1959:1963	cell types	1954:1963	cell types	1954:1963	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	6	72	theme	polymer	1381:1387	arg1	concentrations					1389:1402	polymer concentrations	1381:1402	polymer concentrations	1381:1402	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	4	73	theme	observed	926:933	arg1	responses					935:943	observed responses	926:943	observed responses	926:943	Therefore, if cell responses differ, it may be possible that more than one variable caused the changes in observed responses.					
36044886	0	74	theme	molecular	23:31	arg1	weight					33:38	molecular weight	23:38	molecular weight	23:38	Independent control of molecular weight, concentration, and stiffness of hyaluronic acid hydrogels.					
36044886	9	75	theme	cell	1969:1972	arg1	medium					1982:1987	cell culture medium	1969:1987	cell culture medium	1969:1987	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	6	76	theme	hydrogel	1350:1357	arg1	weights					1369:1375	different HA hydrogel molecular weights	1337:1375	different HA hydrogel molecular weights	1337:1375	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	5	77	theme	multiple	1104:1111	arg1	properties					1122:1131	multiple material properties	1104:1131	multiple material properties	1104:1131	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	2	78	dep	parameters	370:379	arg1	concentration					405:417	concentration	405:417	concentration	405:417	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	78	dep	parameters	370:379	arg1	weight					397:402	molecular weight	387:402	molecular weight	387:402	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	78	dep	parameters	370:379	arg1	etc					431:433	etc	431:433	etc	431:433	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	78	dep	parameters	370:379	arg1	stiffness					420:428	stiffness	420:428	stiffness	420:428	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	2	79	theme	parameters	370:379	arg1	impact					351:356	the impact	347:356	the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto	347:454	Various groups have investigated the impact of hydrogel parameters (e.g. molecular weight, concentration, stiffness, etc)in vitroandin vivoto achieve desired material performance characteristics.					
36044886	6	80	theme	different	1337:1345	arg1	weights					1369:1375	different HA hydrogel molecular weights	1337:1375	different HA hydrogel molecular weights	1337:1375	Independent control was accomplished by tuning the concentration of crosslinker to achieve an effectively constant stiffness for different HA hydrogel molecular weights and polymer concentrations.					
36044886	4	81	from	changes	915:921	arg1	responses					935:943	observed responses	926:943	observed responses	926:943	Therefore, if cell responses differ, it may be possible that more than one variable caused the changes in observed responses.					
36044886	9	82	dep	polymers	1944:1951	arg1	compositions					1989:2000	compositions	1989:2000	compositions	1989:2000	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	5	83	theme	performance	1070:1080	arg1	changes					1082:1088	material performance changes	1061:1088	material performance changes	1061:1088	In the current study, we leveraged thiol-ene click chemistry with a crosslinker to develop a method that minimizes material performance changes and permitted multiple material properties to be independently held constant to evaluate a single variable at a time.					
36044886	9	84	theme	confounding	2014:2024	arg1	variables					2026:2034	confounding variables	2014:2034	confounding variables in experimental hydrogel designs	2014:2067	The methodology presented to achieve independent control of hydrogel parameters may potentially be adopted by others for alternative hydrogel polymers, cell types, or cell culture medium compositions to minimize confounding variables in experimental hydrogel designs.					
36044886	3	85	theme	hydrogel	641:648	arg1	variable					680:687	a 'controlled variable'	666:688	a 'controlled variable'	666:688	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36044886	3	85	theme	hydrogel	641:648	arg1	characteristic					650:663	a given hydrogel characteristic	633:663	a given hydrogel characteristic (a 'controlled variable')	633:689	A limitation in the literature to date has been that altering one hydrogel parameter (a 'manipulated variable') to achieve a given hydrogel characteristic (a 'controlled variable') changes two variables at a time (e.g. altering molecular weight and/or concentration to investigate cell response to stiffness).					
36054216	3	0	with	molecules	624:632	arg1	expectations					663:674	promising expectations	653:674	promising expectations for exosomes	653:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	7	1	with	system	1332:1337	arg1	NaCl					1359:1362	NaCl	1359:1362	NaCl	1359:1362	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	6	2	theme	systems	1079:1085	arg1	4					1067:1067	4	1067:1067	4	1067:1067	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	6	2	theme	systems	1079:1085	arg1	systems					1079:1085	the 20 systems	1072:1085	the 20 systems	1072:1085	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	2	3	theme	methods	503:509	arg1	one					392:394	one	392:394	one	392:394	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	2	3	theme	methods	503:509	arg1	challenges					409:418	the major challenges	399:418	the major challenges for therapeutic applications of exosomes	399:459	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	2	3	theme	methods	503:509	arg1	development					468:478	the development	464:478	the development of optimized isolation methods	464:509	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	1	4	theme	personalized	359:370	arg1	treatments					372:381	prognostic, diagnostic and personalized treatments	332:381	prognostic, diagnostic and personalized treatments	332:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	5	theme	drug	277:280	arg1	biomarkers					317:326	biomarkers	317:326	biomarkers for prognostic, diagnostic and personalized treatments	317:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	5	theme	drug	277:280	arg1	systems					291:297	drug delivery systems	277:297	drug delivery systems for drug therapy	277:314	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	7	6	theme	gmol-1	1302:1307	arg1	system					1332:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	8	7	from	phase	1503:1507	arg1	factor					1471:1476	an exosome purification factor	1447:1476	an exosome purification factor of 2 in the top PEG-rich phase	1447:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	3	8	theme	aqueous	529:535	arg1	method					595:600	an alternative method	580:600	an alternative method to isolate biological molecules and particles with promising expectations for exosomes	580:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	8	theme	aqueous	529:535	arg1	ATPS					556:559	ATPS	556:559	ATPS	556:559	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	8	theme	aqueous	529:535	arg1	systems					547:553	aqueous two-phase systems	529:553	aqueous two-phase systems (ATPS)	529:560	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	7	9	theme	potential	1381:1389	arg1	efficiency					1401:1410	the best potential isolation efficiency	1372:1410	the best potential isolation efficiency	1372:1410	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	1	10	theme	delivery	282:289	arg1	biomarkers					317:326	biomarkers	317:326	biomarkers for prognostic, diagnostic and personalized treatments	317:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	10	theme	delivery	282:289	arg1	systems					291:297	drug delivery systems	277:297	drug delivery systems for drug therapy	277:314	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	6	11	theme	initial	1152:1158	arg1	conditions					1160:1169	initial conditions	1152:1169	initial conditions	1152:1169	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	6	12	theme	mM	1249:1250	arg1	concentration					1229:1241	a final concentration	1221:1241	a final concentration of 25 mM	1221:1250	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	8	13	theme	selective	1586:1594	arg1	recovery					1596:1603	the selective recovery	1582:1603	the selective recovery of these promising nanovesicles	1582:1635	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	4	14	theme	culture	764:770	arg1	media					772:776	culture media	764:776	culture media	764:776	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	6	15	theme	best	1101:1104	arg1	fractionation					1114:1126	the best exosome fractionation	1097:1126	the best exosome fractionation from contaminants	1097:1144	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	0	16	theme	cell-derived	123:134	arg1	exosomes					136:143	CaCo2 cell-derived exosomes	117:143	CaCo2 cell-derived exosomes	117:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	8	17	theme	2	1481:1481	arg1	factor					1471:1476	an exosome purification factor	1447:1476	an exosome purification factor of 2 in the top PEG-rich phase	1447:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	6	18	theme	partition	1047:1055	arg1	analysis					1057:1064	partition analysis	1047:1064	partition analysis	1047:1064	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	7	19	theme	PEG	1291:1293	arg1	system					1332:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	1	20	theme	attractive	194:203	arg1	size					234:237	nano size	229:237	nano size	229:237	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	20	theme	attractive	194:203	arg1	structure					250:258	unique structure	243:258	unique structure	243:258	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	20	theme	attractive	194:203	arg1	characteristics					205:219	attractive characteristics	194:219	attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments	194:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	0	21	theme	CaCo2	117:121	arg1	exosomes					136:143	CaCo2 cell-derived exosomes	117:143	CaCo2 cell-derived exosomes	117:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	8	22	theme	top	1490:1492	arg1	phase					1503:1507	the top PEG-rich phase	1486:1507	the top PEG-rich phase	1486:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	0	23	theme	aqueous	53:59	arg1	systems					71:77	polymer-polymer aqueous two-phase systems	37:77	polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes	37:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	7	24	theme	best	1376:1379	arg1	efficiency					1401:1410	the best potential isolation efficiency	1372:1410	the best potential isolation efficiency	1372:1410	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	7	25	theme	-Dextran	1309:1316	arg1	system					1332:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	3	26	used	used	572:575	arg2	systems					547:553	aqueous two-phase systems	529:553	aqueous two-phase systems (ATPS)	529:560	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	26	used	used	572:575	arg2	ATPS					556:559	ATPS	556:559	ATPS	556:559	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	26	used	used	572:575	arg2	method					595:600	an alternative method	580:600	an alternative method to isolate biological molecules and particles with promising expectations for exosomes	580:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	6	27	dep	presented	1087:1095	arg1	optimized					1183:1191	optimized	1183:1191	were optimized via salt addition (NaCl) to a final concentration of 25 mM	1178:1250	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	4	28	theme	cell	750:753	arg1	line					755:758	CaCo2 cell line	744:758	CaCo2 cell line	744:758	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	5	29	theme	polymer	887:893	arg1	composition					895:905	polymer composition	887:905	polymer composition	887:905	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	6	30	theme	salt	1197:1200	arg1	addition					1202:1209	salt addition	1197:1209	salt addition (NaCl) to a final concentration of 25 mM	1197:1250	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	6	30	theme	salt	1197:1200	arg1	NaCl					1212:1215	NaCl	1212:1215	NaCl	1212:1215	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	6	31	theme	final	1223:1227	arg1	concentration					1229:1241	a final concentration	1221:1241	a final concentration of 25 mM	1221:1250	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	8	32	theme	exosome	1450:1456	arg1	factor					1471:1476	an exosome purification factor	1447:1476	an exosome purification factor of 2 in the top PEG-rich phase	1447:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	0	33	dep	isolation	87:95	arg1	the					83:85	the	83:85	the	83:85	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	2	34	theme	major	403:407	arg1	challenges					409:418	the major challenges	399:418	the major challenges for therapeutic applications of exosomes	399:459	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	7	35	theme	isolation	1391:1399	arg1	efficiency					1401:1410	the best potential isolation efficiency	1372:1410	the best potential isolation efficiency	1372:1410	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	2	36	theme	exosomes	452:459	arg1	applications					436:447	therapeutic applications	424:447	therapeutic applications of exosomes	424:459	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	1	37	theme	drug	303:306	arg1	therapy					308:314	drug therapy	303:314	drug therapy	303:314	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	3	38	with	particles	638:646	arg1	expectations					663:674	promising expectations	653:674	promising expectations for exosomes	653:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	6	39	from	contaminants	1133:1144	arg1	fractionation					1114:1126	the best exosome fractionation	1097:1126	the best exosome fractionation from contaminants	1097:1144	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	1	40	theme	nano	229:232	arg1	size					234:237	nano size	229:237	nano size	229:237	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	4	41	theme	CaCo2	744:748	arg1	line					755:758	CaCo2 cell line	744:758	CaCo2 cell line	744:758	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	0	42	theme	exosomes	136:143	arg1	isolation					87:95	isolation	87:95	isolation	87:95	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	0	42	theme	exosomes	136:143	arg1	purification					101:112	purification	101:112	purification	101:112	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	3	43	theme	promising	653:661	arg1	expectations					663:674	promising expectations	653:674	promising expectations for exosomes	653:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	5	44	theme	polyethylene	955:966	arg1	PEG					976:978	PEG	976:978	PEG	976:978	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	44	theme	polyethylene	955:966	arg1	glycol					968:973	polyethylene glycol	955:973	polyethylene glycol (PEG)	955:979	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	7	45	from	%	1348:1348	arg1	system					1332:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	2	46	theme	therapeutic	424:434	arg1	applications					436:447	therapeutic applications	424:447	therapeutic applications of exosomes	424:459	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	2	47	theme	isolation	493:501	arg1	methods					503:509	optimized isolation methods	483:509	optimized isolation methods	483:509	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	5	48	theme	tie-line	930:937	arg1	TLL					947:949	TLL	947:949	TLL	947:949	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	48	theme	tie-line	930:937	arg1	length					939:944	tie-line length	930:944	tie-line length (TLL)	930:950	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	1	49	link	cell-derived	159:170	arg1	Exosomes					146:153	Exosomes	146:153	Exosomes	146:153	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	49	link	cell-derived	159:170	arg1	vesicles					172:179	cell-derived vesicles	159:179	cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments	159:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	5	50	theme	PEG-Ficoll	1009:1018	arg1	systems					1020:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	51	theme	design	861:866	arg1	weight					918:923	molecular weight	908:923	molecular weight	908:923	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	51	theme	design	861:866	arg1	parameters					868:877	design parameters	861:877	design parameters such as polymer composition, molecular weight, and tie-line length (TLL)	861:950	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	51	theme	design	861:866	arg1	length					939:944	tie-line length	930:944	tie-line length (TLL)	930:950	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	5	51	theme	design	861:866	arg1	composition					895:905	polymer composition	887:905	polymer composition	887:905	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	0	52	theme	polymer-polymer	37:51	arg1	systems					71:77	polymer-polymer aqueous two-phase systems	37:77	polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes	37:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	2	53	theme	optimized	483:491	arg1	methods					503:509	optimized isolation methods	483:509	optimized isolation methods	483:509	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	4	54	theme	polymer-polymer	825:839	arg1	ATPS					841:844	20 polymer-polymer ATPS	822:844	20 polymer-polymer ATPS	822:844	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	5	55	theme	parameters	868:877	arg1	effect					851:856	The effect	847:856	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	847:1026	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	1	56	theme	unique	243:248	arg1	structure					250:258	unique structure	243:258	unique structure	243:258	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	0	57	theme	systems	71:77	arg1	optimization					21:32	optimization	21:32	optimization	21:32	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	0	57	theme	systems	71:77	arg1	Characterization					0:15	Characterization	0:15	Characterization	0:15	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	8	58	theme	PEG-rich	1494:1501	arg1	phase					1503:1507	the top PEG-rich phase	1486:1507	the top PEG-rich phase	1486:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	7	59	theme	TLL	1342:1344	arg1	%					1348:1348	TLL 25% w/w	1342:1352	TLL 25% w/w	1342:1352	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	8	60	from	factor	1471:1476	arg1	phase					1503:1507	the top PEG-rich phase	1486:1507	the top PEG-rich phase	1486:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	4	61	theme	exosomes	721:728	arg1	fractionation					704:716	fractionation	704:716	fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants	704:789	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	0	62	theme	two-phase	61:69	arg1	systems					71:77	polymer-polymer aqueous two-phase systems	37:77	polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes	37:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	1	63	theme	prognostic	332:341	arg1	treatments					372:381	prognostic, diagnostic and personalized treatments	332:381	prognostic, diagnostic and personalized treatments	332:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	8	64	theme	purification	1458:1469	arg1	factor					1471:1476	an exosome purification factor	1447:1476	an exosome purification factor of 2 in the top PEG-rich phase	1447:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	3	65	theme	alternative	583:593	arg1	method					595:600	an alternative method	580:600	an alternative method to isolate biological molecules and particles with promising expectations for exosomes	580:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	65	theme	alternative	583:593	arg1	systems					547:553	aqueous two-phase systems	529:553	aqueous two-phase systems (ATPS)	529:560	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	5	66	from	effect	851:856	arg1	systems					1020:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	4	67	dep	line	755:758	arg1	contaminants					778:789	contaminants	778:789	contaminants	778:789	In this work, fractionation of exosomes obtained from CaCo2 cell line and culture media contaminants were individually performed in 20 polymer-polymer ATPS.					
36054216	7	68	theme	gmol-1	1325:1330	arg1	system					1332:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system	1287:1337	The PEG 10,000 gmol-1 -Dextran 10,000 gmol-1 system at TLL 25% w/w with NaCl, showed the best potential isolation efficiency.					
36054216	8	69	theme	proposed	1428:1435	arg1	strategy					1437:1444	this proposed strategy	1423:1444	this proposed strategy	1423:1444	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	5	70	theme	-Dextran	980:987	arg1	systems					1020:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	6	71	theme	exosome	1106:1112	arg1	fractionation					1114:1126	the best exosome fractionation	1097:1126	the best exosome fractionation from contaminants	1097:1144	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	6	72	theme	collection	1264:1273	arg1	efficiency					1275:1284	collection efficiency	1264:1284	collection efficiency	1264:1284	After partition analysis, 4 of the 20 systems presented the best exosome fractionation from contaminants under initial conditions, which were optimized via salt addition (NaCl) to a final concentration of 25 mM, to improve collection efficiency.					
36054216	0	73	link	cell-derived	123:134	arg1	exosomes					136:143	CaCo2 cell-derived exosomes	117:143	CaCo2 cell-derived exosomes	117:143	Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.					
36054216	5	74	theme	molecular	908:916	arg1	weight					918:923	molecular weight	908:923	molecular weight	908:923	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	8	75	theme	nanovesicles	1624:1635	arg1	recovery					1596:1603	the selective recovery	1582:1603	the selective recovery of these promising nanovesicles	1582:1635	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	2	76	theme	challenges	409:418	arg1	one					392:394	one	392:394	one	392:394	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	2	76	theme	challenges	409:418	arg1	development					468:478	the development	464:478	the development of optimized isolation methods	464:509	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	2	76	theme	challenges	409:418	arg1	challenges					409:418	the major challenges	399:418	the major challenges for therapeutic applications of exosomes	399:459	So far, one of the major challenges for therapeutic applications of exosomes is the development of optimized isolation methods.					
36054216	5	77	theme	Dextran-Ficoll	990:1003	arg1	systems					1020:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems	955:1026	The effect of design parameters such as polymer composition, molecular weight, and tie-line length (TLL) on polyethylene glycol (PEG)-Dextran, Dextran-Ficoll and PEG-Ficoll systems was studied.					
36054216	8	78	contain	have	1559:1562	arg1	ATPS					1554:1557	ATPS	1554:1557	ATPS	1554:1557	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	8	78	contain	have	1559:1562	arg2	potential					1568:1576	the potential	1564:1576	the potential for the selective recovery of these promising nanovesicles	1564:1635	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	1	79	theme	cell-derived	159:170	arg1	Exosomes					146:153	Exosomes	146:153	Exosomes	146:153	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	1	79	theme	cell-derived	159:170	arg1	vesicles					172:179	cell-derived vesicles	159:179	cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments	159:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	8	80	theme	promising	1614:1622	arg1	nanovesicles					1624:1635	these promising nanovesicles	1608:1635	these promising nanovesicles	1608:1635	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36054216	1	81	theme	diagnostic	344:353	arg1	treatments					372:381	prognostic, diagnostic and personalized treatments	332:381	prognostic, diagnostic and personalized treatments	332:381	Exosomes are cell-derived vesicles that present attractive characteristics such as nano size and unique structure for their use as drug delivery systems for drug therapy, biomarkers for prognostic, diagnostic and personalized treatments.					
36054216	3	82	theme	biological	613:622	arg1	molecules					624:632	biological molecules	613:632	biological molecules	613:632	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	83	theme	two-phase	537:545	arg1	method					595:600	an alternative method	580:600	an alternative method to isolate biological molecules and particles with promising expectations for exosomes	580:687	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	83	theme	two-phase	537:545	arg1	ATPS					556:559	ATPS	556:559	ATPS	556:559	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	3	83	theme	two-phase	537:545	arg1	systems					547:553	aqueous two-phase systems	529:553	aqueous two-phase systems (ATPS)	529:560	In this context, aqueous two-phase systems (ATPS) have been used as an alternative method to isolate biological molecules and particles with promising expectations for exosomes.					
36054216	8	84	from	2	1481:1481	arg1	phase					1503:1507	the top PEG-rich phase	1486:1507	the top PEG-rich phase	1486:1507	Following this proposed strategy, an exosome purification factor of 2 in the top PEG-rich phase can be expected furtherly demonstrating that ATPS have the potential for the selective recovery of these promising nanovesicles.					
36690237	7	0	theme	LC	1254:1255	arg1	hydrogels					1257:1265	the biomineralization LC hydrogels	1232:1265	the biomineralization LC hydrogels	1232:1265	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	3	1	theme	biomineralization	482:498	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	1	2	theme	LC	254:255	arg1	network					273:279	liquid crystal (LC) collagen fiber network	238:279	liquid crystal (LC) collagen fiber network	238:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	3	theme	LC	890:891	arg1	hydrogels					893:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	4	4	theme	bone	582:585	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	3	5	theme	ECM-inspired	469:480	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	1	6	theme	collagen	258:265	arg1	network					273:279	liquid crystal (LC) collagen fiber network	238:279	liquid crystal (LC) collagen fiber network	238:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	7	theme	chitin	875:880	arg1	hydrogels					893:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	3	8	theme	hydrogels	518:526	arg1	kind					456:459	a novel kind	448:459	a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels	448:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	5	9	theme	bone	839:842	arg1	microenvironment					853:868	bone ECM-like microenvironment	839:868	bone ECM-like microenvironment	839:868	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	2	10	theme	bone	301:304	arg1	materials					313:321	bone repair materials	301:321	bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM	301:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	1	11	theme	organic-inorganic	173:189	arg1	material					201:208	an organic-inorganic composite material	170:208	an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network	170:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	11	theme	organic-inorganic	173:189	arg1	matrix					154:159	natural bone extracellular matrix	127:159	natural bone extracellular matrix (ECM)	127:165	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	12	theme	charged	1161:1167	arg1	groups					1174:1179	positively charged -NH2 groups	1150:1179	positively charged -NH2 groups	1150:1179	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	5	13	theme	organic-inorganic	796:812	arg1	materials					824:832	the organic-inorganic composite materials	792:832	the organic-inorganic composite materials with bone ECM-like microenvironment	792:868	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	8	14	theme	LC	1478:1479	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	6	15	theme	protein	939:945	arg1	adsorption					947:956	protein adsorption	939:956	protein adsorption	939:956	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	1	16	theme	bone	135:138	arg1	matrix					154:159	natural bone extracellular matrix	127:159	natural bone extracellular matrix (ECM)	127:165	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	16	theme	bone	135:138	arg1	ECM					162:164	ECM	162:164	ECM	162:164	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	16	theme	bone	135:138	arg1	material					201:208	an organic-inorganic composite material	170:208	an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network	170:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	7	17	theme	biomineralization	1236:1252	arg1	hydrogels					1257:1265	the biomineralization LC hydrogels	1232:1265	the biomineralization LC hydrogels	1232:1265	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	7	18	theme	LC	1218:1219	arg1	hydrogels					1221:1229	the pristine LC hydrogels	1205:1229	the pristine LC hydrogels	1205:1229	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	2	19	theme	natural	393:399	arg1	ECM					406:408	natural bone ECM	393:408	natural bone ECM	393:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	7	20	theme	bone-like	1353:1361	arg1	hydroxyapatite					1363:1376	bone-like hydroxyapatite	1353:1376	bone-like hydroxyapatite	1353:1376	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	1	21	theme	fiber	267:271	arg1	network					273:279	liquid crystal (LC) collagen fiber network	238:279	liquid crystal (LC) collagen fiber network	238:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	0	22	theme	biomineralization	18:34	arg1	hydrogels					66:74	biomineralization chitin whisker liquid crystal hydrogels	18:74	biomineralization chitin whisker liquid crystal hydrogels for bone regeneration	18:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	1	23	theme	cell	115:118	arg1	niche					120:124	a particular cell niche	102:124	a particular cell niche	102:124	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	7	24	theme	ECM-like	1329:1336	arg1	texture					1341:1347	their bone ECM-like LC texture	1318:1347	their bone ECM-like LC texture	1318:1347	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	4	25	theme	chitin	549:554	arg1	hydrogels					567:575	photocurable chitin whisker LC hydrogels	536:575	photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity	536:638	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	2	26	theme	ECM	406:408	arg1	components					379:388	the LC characteristic and composite components	343:388	the LC characteristic and composite components of natural bone ECM	343:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	0	27	theme	whisker	43:49	arg1	hydrogels					66:74	biomineralization chitin whisker liquid crystal hydrogels	18:74	biomineralization chitin whisker liquid crystal hydrogels for bone regeneration	18:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	5	28	theme	natural	762:768	arg1	bone					770:773	natural bone	762:773	natural bone	762:773	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	6	29	theme	-COOH	1038:1042	arg1	groups					1044:1049	negatively charged -COOH groups	1019:1049	negatively charged -COOH groups	1019:1049	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	8	30	theme	bone	1427:1430	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	0	31	theme	crystal	58:64	arg1	hydrogels					66:74	biomineralization chitin whisker liquid crystal hydrogels	18:74	biomineralization chitin whisker liquid crystal hydrogels for bone regeneration	18:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	8	32	theme	biomineralization	1445:1461	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	3	33	theme	novel	450:454	arg1	kind					456:459	a novel kind	448:459	a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels	448:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	7	34	theme	osteogenesis	1290:1301	arg1	ability					1303:1309	more favorable osteogenesis ability	1275:1309	more favorable osteogenesis ability	1275:1309	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	4	35	theme	ECM-like	587:594	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	8	36	theme	whisker	1470:1476	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	3	37	theme	chitin	500:505	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	1	38	theme	liquid	238:243	arg1	network					273:279	liquid crystal (LC) collagen fiber network	238:279	liquid crystal (LC) collagen fiber network	238:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	39	theme	superior	911:918	arg1	biomineralization					920:936	superior biomineralization	911:936	superior biomineralization	911:936	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	6	40	theme	desirable	1105:1113	arg1	activity					1126:1133	more desirable osteogenic activity	1100:1133	more desirable osteogenic activity than that with positively charged -NH2 groups	1100:1179	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	4	41	theme	nematic	603:609	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	2	42	theme	LC	347:348	arg1	components					379:388	the LC characteristic and composite components	343:388	the LC characteristic and composite components of natural bone ECM	343:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	4	43	theme	LC	564:565	arg1	hydrogels					567:575	photocurable chitin whisker LC hydrogels	536:575	photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity	536:638	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	6	44	theme	whisker	882:888	arg1	hydrogels					893:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels	871:901	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	3	45	theme	LC	515:516	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	2	46	theme	repair	306:311	arg1	materials					313:321	bone repair materials	301:321	bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM	301:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	5	47	theme	ECM-like	844:851	arg1	microenvironment					853:868	bone ECM-like microenvironment	839:868	bone ECM-like microenvironment	839:868	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	6	48	theme	-NH2	1169:1172	arg1	groups					1174:1179	positively charged -NH2 groups	1150:1179	positively charged -NH2 groups	1150:1179	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	5	49	theme	LC	688:689	arg1	hydrogels					691:699	LC hydrogels	688:699	LC hydrogels	688:699	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	1	50	theme	composite	191:199	arg1	material					201:208	an organic-inorganic composite material	170:208	an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network	170:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	50	theme	composite	191:199	arg1	matrix					154:159	natural bone extracellular matrix	127:159	natural bone extracellular matrix (ECM)	127:165	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	51	theme	osteogenesis	962:973	arg1	ability					975:981	osteogenesis ability	962:981	osteogenesis ability	962:981	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	8	52	theme	hydrogels	1481:1489	arg1	design					1417:1422	the design	1413:1422	the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1413:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	5	53	theme	composite	814:822	arg1	materials					824:832	the organic-inorganic composite materials	792:832	the organic-inorganic composite materials with bone ECM-like microenvironment	792:868	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	8	54	theme	bone	1495:1498	arg1	regeneration					1500:1511	bone regeneration	1495:1511	bone regeneration	1495:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	6	55	with	hydrogel	1005:1012	arg1	groups					1044:1049	negatively charged -COOH groups	1019:1049	negatively charged -COOH groups	1019:1049	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	1	56	theme	natural	127:133	arg1	matrix					154:159	natural bone extracellular matrix	127:159	natural bone extracellular matrix (ECM)	127:165	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	56	theme	natural	127:133	arg1	ECM					162:164	ECM	162:164	ECM	162:164	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	56	theme	natural	127:133	arg1	material					201:208	an organic-inorganic composite material	170:208	an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network	170:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	6	57	theme	charged	1030:1036	arg1	groups					1044:1049	negatively charged -COOH groups	1019:1049	negatively charged -COOH groups	1019:1049	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	0	58	theme	bone	80:83	arg1	regeneration					85:96	bone regeneration	80:96	bone regeneration	80:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	4	59	with	hydrogels	567:575	arg1	viscoelasticity					624:638	viscoelasticity	624:638	viscoelasticity	624:638	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	4	59	with	hydrogels	567:575	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	1	60	theme	extracellular	140:152	arg1	matrix					154:159	natural bone extracellular matrix	127:159	natural bone extracellular matrix (ECM)	127:165	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	60	theme	extracellular	140:152	arg1	ECM					162:164	ECM	162:164	ECM	162:164	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	60	theme	extracellular	140:152	arg1	material					201:208	an organic-inorganic composite material	170:208	an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network	170:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	5	61	theme	mineralization	736:749	arg1	process					751:757	the mineralization process	732:757	the mineralization process	732:757	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	6	62	theme	LC	1002:1003	arg1	hydrogel					1005:1012	LC hydrogel	1002:1012	LC hydrogel with negatively charged -COOH groups	1002:1049	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	7	63	theme	pristine	1209:1216	arg1	hydrogels					1221:1229	the pristine LC hydrogels	1205:1229	the pristine LC hydrogels	1205:1229	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	7	64	theme	LC	1338:1339	arg1	texture					1341:1347	their bone ECM-like LC texture	1318:1347	their bone ECM-like LC texture	1318:1347	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	4	65	theme	photocurable	536:547	arg1	hydrogels					567:575	photocurable chitin whisker LC hydrogels	536:575	photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity	536:638	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	2	66	theme	composite	369:377	arg1	components					379:388	the LC characteristic and composite components	343:388	the LC characteristic and composite components of natural bone ECM	343:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	0	67	theme	chitin	36:41	arg1	hydrogels					66:74	biomineralization chitin whisker liquid crystal hydrogels	18:74	biomineralization chitin whisker liquid crystal hydrogels for bone regeneration	18:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	1	68	theme	network	273:279	arg1	mineralization					220:233	mineralization	220:233	mineralization of liquid crystal (LC) collagen fiber network	220:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	1	69	theme	particular	104:113	arg1	niche					120:124	a particular cell niche	102:124	a particular cell niche	102:124	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36690237	7	70	theme	bone	1324:1327	arg1	texture					1341:1347	their bone ECM-like LC texture	1318:1347	their bone ECM-like LC texture	1318:1347	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	2	71	theme	great	415:419	arg1	challenge					421:429	a great challenge	413:429	a great challenge	413:429	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	4	72	theme	whisker	556:562	arg1	hydrogels					567:575	photocurable chitin whisker LC hydrogels	536:575	photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity	536:638	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	5	73	with	materials	824:832	arg1	microenvironment					853:868	bone ECM-like microenvironment	839:868	bone ECM-like microenvironment	839:868	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	0	74	theme	liquid	51:56	arg1	hydrogels					66:74	biomineralization chitin whisker liquid crystal hydrogels	18:74	biomineralization chitin whisker liquid crystal hydrogels for bone regeneration	18:96	Bone ECM-inspired biomineralization chitin whisker liquid crystal hydrogels for bone regeneration.					
36690237	2	75	theme	bone	401:404	arg1	ECM					406:408	natural bone ECM	393:408	natural bone ECM	393:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	5	76	theme	bone	770:773	arg1	process					751:757	the mineralization process	732:757	the mineralization process	732:757	Next, biomineralization, guided by LC hydrogels, is carried out to truly mimic the mineralization process of natural bone, so as to obtain the organic-inorganic composite materials with bone ECM-like microenvironment.					
36690237	6	77	dep	desirable	1105:1113	arg1	osteogenic					1115:1124	osteogenic	1115:1124	osteogenic	1115:1124	The chitin whisker LC hydrogels exhibit superior biomineralization, protein adsorption and osteogenesis ability, more importantly, LC hydrogel with negatively charged -COOH groups is more conducive to biomineralization and shows more desirable osteogenic activity than that with positively charged -NH2 groups.					
36690237	3	78	theme	bone	464:467	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	7	79	theme	favorable	1280:1288	arg1	ability					1303:1309	more favorable osteogenesis ability	1275:1309	more favorable osteogenesis ability	1275:1309	Notably, compared with the pristine LC hydrogels, the biomineralization LC hydrogels display more favorable osteogenesis ability due to their bone ECM-like LC texture and bone-like hydroxyapatite.					
36690237	4	80	theme	chiral	596:601	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	8	81	theme	ECM-inspired	1432:1443	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	2	82	theme	characteristic	350:363	arg1	components					379:388	the LC characteristic and composite components	343:388	the LC characteristic and composite components of natural bone ECM	343:408	However, designing bone repair materials that highly imitate the LC characteristic and composite components of natural bone ECM is a great challenge.					
36690237	4	83	theme	LC	611:612	arg1	state					614:618	bone ECM-like chiral nematic LC state	582:618	bone ECM-like chiral nematic LC state	582:618	First, photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity are created.					
36690237	8	84	theme	chitin	1463:1468	arg1	hydrogels					1481:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels	1427:1489	bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration	1427:1511	This study opens an avenue toward the design of bone ECM-inspired biomineralization chitin whisker LC hydrogels for bone regeneration.					
36690237	3	85	theme	whisker	507:513	arg1	hydrogels					518:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	bone ECM-inspired biomineralization chitin whisker LC hydrogels	464:526	Here, we report a novel kind of bone ECM-inspired biomineralization chitin whisker LC hydrogels.					
36690237	1	86	theme	crystal	245:251	arg1	network					273:279	liquid crystal (LC) collagen fiber network	238:279	liquid crystal (LC) collagen fiber network	238:279	As a particular cell niche, natural bone extracellular matrix (ECM) is an organic-inorganic composite material formed by mineralization of liquid crystal (LC) collagen fiber network.					
36931881	4	0	theme	organ´s	817:823	arg1	mellitus					897:904	post-transplant diabetes mellitus	872:904	post-transplant diabetes mellitus	872:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	0	theme	organ´s	817:823	arg1	infections					825:834	organ´s infections	817:834	organ´s infections	817:834	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	1	theme	range	489:493	arg1	occurrence					468:477	the occurrence	464:477	the occurrence of a wide range of complications	464:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	2	theme	post-transplantation	1252:1271	arg1	period					1273:1278	the post-transplantation period	1248:1278	the post-transplantation period	1248:1278	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	5	3	from	influence	929:937	arg1	metabolism					986:995	metabolism	986:995	metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	986:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	5	4	theme	graft	1179:1183	arg1	rejection					1185:1193	graft rejection	1179:1193	graft rejection	1179:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	2	5	theme	complications	498:510	arg1	range					489:493	a wide range	482:493	a wide range of complications	482:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	5	6	with	immunosuppressants	1000:1017	arg1	production					1028:1037	the production	1024:1037	the production of less effective components	1024:1066	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	5	6	with	immunosuppressants	1000:1017	arg1	necessity					1087:1095	the subsequent necessity	1072:1095	the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	1072:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	6	7	theme	gut	1230:1232	arg1	microbiome					1234:1243	the gut microbiome	1226:1243	the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA)	1226:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	2	8	theme	body	223:226	arg1	functions					204:212	the functions	200:212	the functions of human body	200:226	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	9	theme	diarrhoea	806:814	arg1	fibrosis					747:754	interstitial fibrosis	734:754	interstitial fibrosis	734:754	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	9	theme	diarrhoea	806:814	arg1	atrophy					768:774	tubular atrophy	760:774	tubular atrophy	760:774	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	9	theme	diarrhoea	806:814	arg1	rejection					723:731	acute rejection	717:731	acute rejection	717:731	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	10	theme	wide	484:487	arg1	range					489:493	a wide range	482:493	a wide range of complications	482:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	11	theme	occurrence	468:477	arg1	context					453:459	the context	449:459	the context of the occurrence of a wide range of complications	449:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	12	theme	chain	1317:1321	arg1	SCFA					1336:1339	SCFA	1336:1339	SCFA	1336:1339	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	12	theme	chain	1317:1321	arg1	acids					1329:1333	short chain fatty acids	1311:1333	short chain fatty acids (SCFA)	1311:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	7	13	theme	many	1585:1588	arg1	others					1590:1595	many others	1585:1595	many others	1585:1595	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	6	14	theme	composition	1211:1221	arg1	Support					1196:1202	Support	1196:1202	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA)	1196:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	2	15	dep	infuence	191:198	arg1	clarify					287:293	clarify	287:293	to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	284:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	5	16	theme	components	1057:1066	arg1	production					1028:1037	the production	1024:1037	the production of less effective components	1024:1066	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	5	16	theme	components	1057:1066	arg1	necessity					1087:1095	the subsequent necessity	1072:1095	the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	1072:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	3	17	theme	Kidney	513:518	arg1	transplantation					520:534	Kidney transplantation	513:534	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics	513:596	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	7	18	theme	tolerance	1571:1579	arg1	induction					1543:1551	the induction	1539:1551	the induction of donor-specific tolerance and many others	1539:1595	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	4	19	theme	complications	850:862	arg1	fibrosis					747:754	interstitial fibrosis	734:754	interstitial fibrosis	734:754	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	19	theme	complications	850:862	arg1	atrophy					768:774	tubular atrophy	760:774	tubular atrophy	760:774	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	19	theme	complications	850:862	arg1	rejection					723:731	acute rejection	717:731	acute rejection	717:731	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	20	from	graft	424:428	arg1	context					453:459	the context	449:459	the context of the occurrence of a wide range of complications	449:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	21	theme	subsequent	645:654	arg1	development					656:666	The subsequent development	641:666	The subsequent development of dysbiosis	641:679	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	5	22	dep	influence	929:937	arg1	important					912:920	important	912:920	important	912:920	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	3	23	theme	subsequent	545:554	arg1	use					556:558	the subsequent use	541:558	the subsequent use of immunosuppressants and antibiotics	541:596	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	1	24	theme	medicine	115:122	arg1	branches					103:110	many branches	98:110	many branches of medicine	98:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	4	25	theme	diabetes	888:895	arg1	mellitus					897:904	post-transplant diabetes mellitus	872:904	post-transplant diabetes mellitus	872:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	6	26	from	microbiome	1234:1243	arg1	favor					1283:1287	favor	1283:1287	favor	1283:1287	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	26	from	microbiome	1234:1243	arg1	period					1273:1278	the post-transplantation period	1248:1278	the post-transplantation period	1248:1278	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	7	27	theme	graft	1656:1660	arg1	survival					1662:1669	graft survival	1656:1669	graft survival	1656:1669	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	28	from	period	364:369	arg1	function					381:388	their function	375:388	their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	375:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	28	from	period	364:369	arg1	composition					306:316	composition	306:316	composition of gut microbiome in the post-transplantation period	306:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	7	29	theme	patient	1644:1650	arg1	quality					1633:1639	the quality	1629:1639	the quality of patient and graft survival	1629:1669	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	7	30	theme	metabolic	1512:1520	arg1	compensation					1522:1533	metabolic compensation	1512:1533	metabolic compensation	1512:1533	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	31	theme	patient	438:444	arg1	survival					408:415	the long-term survival	394:415	the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	394:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	32	theme	rejection	723:731	arg1	risk					709:712	the risk	705:712	the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus	705:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	33	theme	gut	321:323	arg1	microbiome					325:334	gut microbiome	321:334	gut microbiome in the post-transplantation period	321:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	34	with	diet	1369:1372	arg1	predominance					1379:1390	predominance	1379:1390	predominance of fiber, the application of probiotics, prebiotics	1379:1442	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	5	35	theme	microorganisms	946:959	arg1	influence					929:937	the influence	925:937	the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	925:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	0	36	theme	Gut	0:2	arg1	microbiome					4:13	Gut microbiome	0:13	Gut microbiome	0:13	Gut microbiome and renal transplantation.					
36931881	5	37	theme	underdosing	1145:1155	arg1	risk					1137:1140	a higher risk	1128:1140	a higher risk of underdosing	1128:1155	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	5	37	theme	underdosing	1145:1155	arg1	occurrence					1165:1174	the occurrence	1161:1174	the occurrence of graft rejection	1161:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	7	38	theme	overall	1606:1612	arg1	improvement					1614:1624	an overall improvement	1603:1624	an overall improvement in the quality of patient and graft survival	1603:1669	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	39	theme	post-transplantation	343:362	arg1	period					364:369	the post-transplantation period	339:369	the post-transplantation period	339:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	40	theme	main	148:151	arg1	aim					153:155	Our main aim	144:155	Our main aim	144:155	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	41	theme	atrophy	768:774	arg1	risk					709:712	the risk	705:712	the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus	705:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	6	42	from	favor	1283:1287	arg1	composition					1211:1221	the composition	1207:1221	the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA)	1207:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	2	43	from	composition	306:316	arg1	period					364:369	the post-transplantation period	339:369	the post-transplantation period	339:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	44	theme	other	273:277	arg1	hand					279:282	the other hand	269:282	the other hand	269:282	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	5	45	theme	immunosuppressants	1000:1017	arg1	metabolism					986:995	metabolism	986:995	metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	986:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	4	46	theme	interstitial	734:745	arg1	fibrosis					747:754	interstitial fibrosis	734:754	interstitial fibrosis	734:754	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	7	47	theme	available	1458:1466	arg1	studies					1468:1474	available studies	1458:1474	available studies	1458:1474	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	48	from	context	453:459	arg1	survival					408:415	the long-term survival	394:415	the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	394:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	49	theme	fiber	1395:1399	arg1	predominance					1379:1390	predominance	1379:1390	predominance of fiber, the application of probiotics, prebiotics	1379:1442	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	50	from	period	1273:1278	arg1	composition					1211:1221	the composition	1207:1221	the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA)	1207:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	5	51	theme	microbiome	972:981	arg1	microorganisms					946:959	the microorganisms	942:959	the microorganisms of the gut microbiome	942:981	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	6	52	theme	probiotics	1421:1430	arg1	fiber					1395:1399	fiber	1395:1399	fiber	1395:1399	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	52	theme	probiotics	1421:1430	arg1	application					1406:1416	the application	1402:1416	the application of probiotics	1402:1430	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	3	53	theme	gut	625:627	arg1	microbiome					629:638	gut microbiome	625:638	gut microbiome	625:638	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	5	54	theme	rejection	1185:1193	arg1	risk					1137:1140	a higher risk	1128:1140	a higher risk of underdosing	1128:1155	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	5	54	theme	rejection	1185:1193	arg1	occurrence					1165:1174	the occurrence	1161:1174	the occurrence of graft rejection	1161:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	4	55	theme	infections	825:834	arg1	fibrosis					747:754	interstitial fibrosis	734:754	interstitial fibrosis	734:754	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	55	theme	infections	825:834	arg1	atrophy					768:774	tubular atrophy	760:774	tubular atrophy	760:774	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	55	theme	infections	825:834	arg1	rejection					723:731	acute rejection	717:731	acute rejection	717:731	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	6	56	theme	microbiome	1234:1243	arg1	composition					1211:1221	the composition	1207:1221	the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA)	1207:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	7	57	from	benefits	1492:1499	arg1	term					1504:1507	term	1504:1507	term of metabolic compensation	1504:1533	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	4	58	theme	graft	783:787	arg1	fibrosis					747:754	interstitial fibrosis	734:754	interstitial fibrosis	734:754	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	58	theme	graft	783:787	arg1	atrophy					768:774	tubular atrophy	760:774	tubular atrophy	760:774	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	58	theme	graft	783:787	arg1	rejection					723:731	acute rejection	717:731	acute rejection	717:731	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	7	59	theme	others	1590:1595	arg1	induction					1543:1551	the induction	1539:1551	the induction of donor-specific tolerance and many others	1539:1595	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	4	60	theme	post-transplant	790:804	arg1	diarrhoea					806:814	post-transplant diarrhoea	790:814	post-transplant diarrhoea	790:814	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	61	from	changes	295:301	arg1	function					381:388	their function	375:388	their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	375:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	61	from	changes	295:301	arg1	composition					306:316	composition	306:316	composition of gut microbiome in the post-transplantation period	306:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	62	theme	fatty	1323:1327	arg1	SCFA					1336:1339	SCFA	1336:1339	SCFA	1336:1339	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	62	theme	fatty	1323:1327	arg1	acids					1329:1333	short chain fatty acids	1311:1333	short chain fatty acids (SCFA)	1311:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	2	63	theme	immune	247:252	arg1	system					254:259	the immune system	243:259	the immune system	243:259	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	64	theme	post-transplant	872:886	arg1	mellitus					897:904	post-transplant diabetes mellitus	872:904	post-transplant diabetes mellitus	872:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	6	65	theme	short	1311:1315	arg1	SCFA					1336:1339	SCFA	1336:1339	SCFA	1336:1339	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	65	theme	short	1311:1315	arg1	acids					1329:1333	short chain fatty acids	1311:1333	short chain fatty acids (SCFA)	1311:1340	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	5	66	theme	effective	1047:1055	arg1	components					1057:1066	less effective components	1042:1066	less effective components	1042:1066	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	7	67	theme	donor-specific	1556:1569	arg1	tolerance					1571:1579	donor-specific tolerance	1556:1579	donor-specific tolerance	1556:1579	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	68	theme	microbes	179:186	arg1	ability					168:174	ability	168:174	ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	168:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	1	69	theme	many	98:101	arg1	branches					103:110	many branches	98:110	many branches of medicine	98:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	4	70	theme	metabolic	840:848	arg1	mellitus					897:904	post-transplant diabetes mellitus	872:904	post-transplant diabetes mellitus	872:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	70	theme	metabolic	840:848	arg1	complications					850:862	metabolic complications	840:862	metabolic complications such as post-transplant diabetes mellitus	840:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	71	from	patient	438:444	arg1	context					453:459	the context	449:459	the context of the occurrence of a wide range of complications	449:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	7	72	from	improvement	1614:1624	arg1	quality					1633:1639	the quality	1629:1639	the quality of patient and graft survival	1629:1669	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	73	theme	human	217:221	arg1	body					223:226	human body	217:226	human body	217:226	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	6	74	from	composition	1211:1221	arg1	favor					1283:1287	favor	1283:1287	favor	1283:1287	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	6	74	from	composition	1211:1221	arg1	period					1273:1278	the post-transplantation period	1248:1278	the post-transplantation period	1248:1278	Support of the composition of the gut microbiome in the post-transplantation period in favor of bacteria producing short chain fatty acids (SCFA) is possible by changing of diet with predominance of fiber, the application of probiotics, prebiotics.					
36931881	3	75	with	transplantation	520:534	arg1	use					556:558	the subsequent use	541:558	the subsequent use of immunosuppressants and antibiotics	541:596	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	7	76	theme	compensation	1522:1533	arg1	term					1504:1507	term	1504:1507	term of metabolic compensation	1504:1533	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	77	theme	graft	424:428	arg1	survival					408:415	the long-term survival	394:415	the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	394:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	1	78	theme	last	131:134	arg1	decade					136:141	the last decade	127:141	the last decade	127:141	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	7	79	theme	survival	1662:1669	arg1	quality					1633:1639	the quality	1629:1639	the quality of patient and graft survival	1629:1669	According to available studies, it can lead to benefits in term of metabolic compensation, to the induction of donor-specific tolerance and many others, with an overall improvement in the quality of patient and graft survival.					
36931881	2	80	from	function	381:388	arg1	period					364:369	the post-transplantation period	339:369	the post-transplantation period	339:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	5	81	theme	subsequent	1076:1085	arg1	necessity					1087:1095	the subsequent necessity	1072:1095	the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection	1072:1193	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	2	82	from	survival	408:415	arg1	context					453:459	the context	449:459	the context of the occurrence of a wide range of complications	449:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	83	theme	acute	717:721	arg1	rejection					723:731	acute rejection	717:731	acute rejection	717:731	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	4	84	theme	dysbiosis	671:679	arg1	development					656:666	The subsequent development	641:666	The subsequent development of dysbiosis	641:679	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	0	85	theme	renal	19:23	arg1	transplantation					25:39	renal transplantation	19:39	renal transplantation	19:39	Gut microbiome and renal transplantation.					
36931881	1	86	theme	Gut	42:44	arg1	research					57:64	Gut microbiome research	42:64	Gut microbiome research	42:64	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	1	86	theme	Gut	42:44	arg1	surge					77:81	a surge	75:81	a surge of interest in many branches of medicine	75:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	1	87	theme	interest	86:93	arg1	research					57:64	Gut microbiome research	42:64	Gut microbiome research	42:64	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	1	87	theme	interest	86:93	arg1	surge					77:81	a surge	75:81	a surge of interest in many branches of medicine	75:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	3	88	theme	immunosuppressants	563:580	arg1	use					556:558	the subsequent use	541:558	the subsequent use of immunosuppressants and antibiotics	541:596	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	2	89	theme	long-term	398:406	arg1	survival					408:415	the long-term survival	394:415	the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	394:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	4	90	theme	tubular	760:766	arg1	atrophy					768:774	tubular atrophy	760:774	tubular atrophy	760:774	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
36931881	2	91	theme	microbiome	325:334	arg1	function					381:388	their function	375:388	their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications	375:510	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	91	theme	microbiome	325:334	arg1	composition					306:316	composition	306:316	composition of gut microbiome in the post-transplantation period	306:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	5	92	theme	higher	1130:1135	arg1	risk					1137:1140	a higher risk	1128:1140	a higher risk of underdosing	1128:1155	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	1	93	theme	microbiome	46:55	arg1	research					57:64	Gut microbiome research	42:64	Gut microbiome research	42:64	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	1	93	theme	microbiome	46:55	arg1	surge					77:81	a surge	75:81	a surge of interest in many branches of medicine	75:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	3	94	theme	antibiotics	586:596	arg1	use					556:558	the subsequent use	541:558	the subsequent use of immunosuppressants and antibiotics	541:596	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	1	95	from	surge	77:81	arg1	branches					103:110	many branches	98:110	many branches of medicine	98:122	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	1	95	from	surge	77:81	arg1	decade					136:141	the last decade	127:141	the last decade	127:141	Gut microbiome research has been a surge of interest in many branches of medicine in the last decade.					
36931881	5	96	theme	gut	968:970	arg1	microbiome					972:981	the gut microbiome	964:981	the gut microbiome	964:981	Also important is the influence of the microorganisms of the gut microbiome on metabolism of immunosuppressants with the production of less effective components and the subsequent necessity of modifying their levels with a higher risk of underdosing and the occurrence of graft rejection.					
36931881	2	97	from	microbiome	325:334	arg1	period					364:369	the post-transplantation period	339:369	the post-transplantation period	339:369	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	98	dep	ability	168:174	arg1	infuence					191:198	infuence	191:198	infuence	191:198	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	2	98	dep	ability	168:174	arg1	hand					279:282	the other hand	269:282	the other hand	269:282	Our main aim is to show ability of microbes to infuence the functions of human body, especially in the immune system, and on the other hand to clarify changes in composition of gut microbiome in the post-transplantation period and their function for the long-term survival of the graft and the patient in the context of the occurrence of a wide range of complications.					
36931881	3	99	theme	microbiome	629:638	arg1	composition					610:620	the composition	606:620	the composition of gut microbiome	606:638	Kidney transplantation with the subsequent use of immunosuppressants and antibiotics affects the composition of gut microbiome.					
36931881	4	100	theme	fibrosis	747:754	arg1	risk					709:712	the risk	705:712	the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus	705:904	The subsequent development of dysbiosis significantly increases the risk of acute rejection, interstitial fibrosis and tubular atrophy of the graft, post-transplant diarrhoea, organ´s infections and metabolic complications such as post-transplant diabetes mellitus.					
35351474	0	0	theme	carbon	91:96	arg1	nanotube					98:105	intimately coupled carbon nanotube	72:105	intimately coupled carbon nanotube	72:105	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	4	1	from	accumulation	1213:1224	arg1	photocatalysis					1250:1263	the photocatalysis	1246:1263	the photocatalysis	1246:1263	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	2	2	theme	photocatalytic	608:621	arg1	composite					623:631	photocatalytic composite	608:631	photocatalytic composite	608:631	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	3	theme	@	695:695	arg1	SA					696:697	R. palustris/CAT@SA	679:697	R. palustris/CAT@SA	679:697	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	3	theme	@	695:695	arg1	alginate					664:671	sodium alginate	657:671	sodium alginate (SA) (R. palustris/CAT@SA)	657:698	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	1	4	theme	red	246:248	arg1	wastewater					250:259	Congo red wastewater	240:259	Congo red wastewater	240:259	With a large number of Congo red used in textiles, Congo red wastewater was not easily degraded, resulting in environmental and health-related problems.					
35351474	0	5	theme	coupled	83:89	arg1	nanotube					98:105	intimately coupled carbon nanotube	72:105	intimately coupled carbon nanotube	72:105	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	6	6	theme	SA	1556:1557	arg1	solution					1527:1534	A novel technical solution	1509:1534	A novel technical solution of R. palustris/CAT@SA	1509:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	4	7	theme	intermediates	1229:1241	arg1	accumulation					1213:1224	the accumulation	1209:1224	the accumulation of intermediates in the photocatalysis	1209:1263	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	3	8	theme	degradation	786:796	arg1	rates					810:814	the degradation and removal rates	782:814	rates	810:814	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	6	9	theme	@	1555:1555	arg1	SA					1556:1557	R. palustris/CAT@SA	1539:1557	R. palustris/CAT@SA	1539:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	2	10	theme	titanium	591:598	arg1	dioxide					600:606	silver modified titanium dioxide	575:606	silver modified titanium dioxide	575:606	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	11	theme	red	825:827	arg1	rates					810:814	the degradation and removal rates	782:814	rates	810:814	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	5	12	theme	aromatic	1350:1357	arg1	hydrocarbons					1359:1370	aromatic hydrocarbons	1350:1370	aromatic hydrocarbons	1350:1370	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	6	13	theme	palustris/CAT	1542:1554	arg1	SA					1556:1557	R. palustris/CAT@SA	1539:1557	R. palustris/CAT@SA	1539:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	2	14	theme	modified	582:589	arg1	dioxide					600:606	silver modified titanium dioxide	575:606	silver modified titanium dioxide	575:606	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	4	15	theme	product	1106:1112	arg1	radicals					1090:1097	the superoxide and hydroxyl radicals	1062:1097	radicals	1090:1097	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	2	16	theme	Rhodopseudomonas	514:529	arg1	palustris					531:539	coupling Rhodopseudomonas palustris	505:539	coupling Rhodopseudomonas palustris (R. Palustris)	505:554	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	16	theme	Rhodopseudomonas	514:529	arg1	Palustris					545:553	R. Palustris	542:553	R. Palustris	542:553	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	6	17	theme	R.	1539:1540	arg1	SA					1556:1557	R. palustris/CAT@SA	1539:1557	R. palustris/CAT@SA	1539:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	4	18	theme	CAT	1102:1104	arg1	product					1106:1112	CAT product	1102:1112	CAT product	1102:1112	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	2	19	theme	red	398:400	arg1	wastewater					402:411	Congo red wastewater	392:411	Congo red wastewater	392:411	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	20	theme	coupling	505:512	arg1	palustris					531:539	coupling Rhodopseudomonas palustris	505:539	coupling Rhodopseudomonas palustris (R. Palustris)	505:554	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	20	theme	coupling	505:512	arg1	Palustris					545:553	R. Palustris	542:553	R. Palustris	542:553	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	21	theme	CNT-Ag	634:639	arg1	CAT					648:650	CAT	648:650	CAT	648:650	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	21	theme	CNT-Ag	634:639	arg1	-TiO2					641:645	CNT-Ag -TiO2	634:645	CNT-Ag -TiO2	634:645	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	4	22	theme	superoxide	1066:1075	arg1	radicals					1090:1097	the superoxide and hydroxyl radicals	1062:1097	radicals	1090:1097	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	2	23	theme	photocatalysis	441:454	arg1	system					482:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	24	theme	R.	735:736	arg1	palustris					738:746	immobilized CAT and R. palustris	715:746	immobilized CAT and R. palustris	715:746	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	2	25	theme	Congo	392:396	arg1	wastewater					402:411	Congo red wastewater	392:411	Congo red wastewater	392:411	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	5	26	theme	red	1458:1460	arg1	part					1440:1443	a small part	1432:1443	a small part of the Congo red	1432:1460	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	4	27	theme	R.	1181:1182	arg1	Palustris					1184:1192	R. Palustris	1181:1192	R. Palustris	1181:1192	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	6	28	theme	wastewater	1618:1627	arg1	degradation					1599:1609	the degradation	1595:1609	the degradation of dye wastewater	1595:1627	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	1	29	theme	large	196:200	arg1	number					202:207	a large number	194:207	a large number of Congo red used in textiles	194:237	With a large number of Congo red used in textiles, Congo red wastewater was not easily degraded, resulting in environmental and health-related problems.					
35351474	0	30	theme	Rapid	0:4	arg1	degradation					6:16	Rapid degradation	0:16	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver	0:114	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	3	31	theme	immobilized	715:725	arg1	palustris					738:746	immobilized CAT and R. palustris	715:746	immobilized CAT and R. palustris	715:746	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	5	32	theme	carrier	1324:1330	arg1	interior					1308:1315	the interior	1304:1315	the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized	1304:1405	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	4	33	theme	hydroxyl	1081:1088	arg1	radicals					1090:1097	the superoxide and hydroxyl radicals	1062:1097	radicals	1090:1097	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	5	34	theme	R.	1375:1376	arg1	Palustris					1378:1386	R. Palustris	1375:1386	R. Palustris	1375:1386	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	6	35	theme	novel	1511:1515	arg1	solution					1527:1534	A novel technical solution	1509:1534	A novel technical solution of R. palustris/CAT@SA	1509:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	2	36	theme	coupled	433:439	arg1	photocatalysis					441:454	intimately coupled photocatalysis	422:454	intimately coupled photocatalysis	422:454	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	37	theme	CAT	727:729	arg1	palustris					738:746	immobilized CAT and R. palustris	715:746	immobilized CAT and R. palustris	715:746	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	0	38	theme	dioxide	134:140	arg1	composite					157:165	titanium dioxide photocatalytic composite	125:165	titanium dioxide photocatalytic composite	125:165	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	2	39	theme	sodium	657:662	arg1	alginate					664:671	sodium alginate	657:671	sodium alginate (SA) (R. palustris/CAT@SA)	657:698	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	39	theme	sodium	657:662	arg1	SA					696:697	R. palustris/CAT@SA	679:697	R. palustris/CAT@SA	679:697	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	39	theme	sodium	657:662	arg1	SA					674:675	SA	674:675	SA	674:675	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	40	dep	order	345:349	arg1	improve					354:360	improve	354:360	to improve the degradation efficiency of Congo red wastewater	351:411	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	41	theme	COD	857:859	arg1	rates					869:873	the COD removal rates	853:873	the COD removal rates	853:873	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	2	42	theme	novel	416:420	arg1	system					482:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	6	43	theme	potential	1570:1578	arg1	application					1580:1590	a potential application	1568:1590	a potential application to the degradation of dye wastewater	1568:1627	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	0	44	theme	titanium	125:132	arg1	dioxide					134:140	titanium dioxide	125:140	titanium dioxide photocatalytic composite	125:165	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	6	45	theme	technical	1517:1525	arg1	solution					1527:1534	A novel technical solution	1509:1534	A novel technical solution of R. palustris/CAT@SA	1509:1557	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	0	46	dep	palustris	62:70	arg1	nanotube					98:105	intimately coupled carbon nanotube	72:105	intimately coupled carbon nanotube	72:105	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	0	47	theme	wastewater	31:40	arg1	degradation					6:16	Rapid degradation	0:16	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver	0:114	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	4	48	theme	long-chain	1128:1137	arg1	alkanes					1139:1145	the long-chain alkanes	1124:1145	the long-chain alkanes	1124:1145	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	4	48	theme	long-chain	1128:1137	arg1	mineralization					1163:1176	mineralization	1163:1176	mineralization	1163:1176	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	1	49	theme	red	218:220	arg1	number					202:207	a large number	194:207	a large number of Congo red used in textiles	194:237	With a large number of Congo red used in textiles, Congo red wastewater was not easily degraded, resulting in environmental and health-related problems.					
35351474	0	50	theme	red	27:29	arg1	wastewater					31:40	Congo red wastewater	21:40	Congo red wastewater	21:40	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	0	51	theme	photocatalytic	142:155	arg1	composite					157:165	titanium dioxide photocatalytic composite	125:165	titanium dioxide photocatalytic composite	125:165	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	4	52	theme	degradation	928:938	arg1	mechanism					911:919	The mechanism	907:919	The mechanism of the degradation of Congo red by the new ICPB	907:967	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	2	53	theme	palustris/CAT	682:694	arg1	SA					696:697	R. palustris/CAT@SA	679:697	R. palustris/CAT@SA	679:697	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	53	theme	palustris/CAT	682:694	arg1	alginate					664:671	sodium alginate	657:671	sodium alginate (SA) (R. palustris/CAT@SA)	657:698	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	54	theme	wastewater	402:411	arg1	efficiency					378:387	the degradation efficiency	362:387	the degradation efficiency of Congo red wastewater	362:411	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	0	55	theme	Rhodopseudomonas	45:60	arg1	palustris					62:70	Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver	45:114	palustris	62:70	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	1	56	theme	environmental	299:311	arg1	problems					332:339	environmental and health-related problems	299:339	environmental and health-related problems	299:339	With a large number of Congo red used in textiles, Congo red wastewater was not easily degraded, resulting in environmental and health-related problems.					
35351474	0	57	theme	sodium	172:177	arg1	alginate					179:186	sodium alginate	172:186	sodium alginate	172:186	Rapid degradation of Congo red wastewater by Rhodopseudomonas palustris intimately coupled carbon nanotube - Silver modified titanium dioxide photocatalytic composite with sodium alginate.					
35351474	6	58	theme	dye	1614:1616	arg1	wastewater					1618:1627	dye wastewater	1614:1627	dye wastewater	1614:1627	A novel technical solution of R. palustris/CAT@SA provided a potential application to the degradation of dye wastewater.					
35351474	2	59	theme	R.	679:680	arg1	SA					696:697	R. palustris/CAT@SA	679:697	R. palustris/CAT@SA	679:697	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	59	theme	R.	679:680	arg1	alginate					664:671	sodium alginate	657:671	sodium alginate (SA) (R. palustris/CAT@SA)	657:698	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	60	theme	R.	542:543	arg1	palustris					531:539	coupling Rhodopseudomonas palustris	505:539	coupling Rhodopseudomonas palustris (R. Palustris)	505:554	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	60	theme	R.	542:543	arg1	Palustris					545:553	R. Palustris	542:553	R. Palustris	542:553	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	61	theme	biodegradation	460:473	arg1	system					482:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	A novel intimately coupled photocatalysis and biodegradation (ICPB) system	414:487	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	62	theme	removal	861:867	arg1	rates					869:873	the COD removal rates	853:873	the COD removal rates	853:873	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	4	63	theme	new	960:962	arg1	ICPB					964:967	the new ICPB	956:967	the new ICPB	956:967	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	1	64	theme	health-related	317:330	arg1	problems					332:339	environmental and health-related problems	299:339	environmental and health-related problems	299:339	With a large number of Congo red used in textiles, Congo red wastewater was not easily degraded, resulting in environmental and health-related problems.					
35351474	5	65	theme	R.	1495:1496	arg1	Palustris					1498:1506	R. Palustris	1495:1506	R. Palustris	1495:1506	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	3	66	theme	palustris/CAT	756:768	arg1	SA					770:771	the R. palustris/CAT@SA	749:771	the R. palustris/CAT@SA	749:771	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	2	67	theme	carbon	557:562	arg1	nanotube					564:571	carbon nanotube	557:571	carbon nanotube	557:571	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	4	68	theme	long-chain	1040:1049	arg1	alkanes					1051:1057	long-chain alkanes	1040:1057	long-chain alkanes	1040:1057	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	4	69	theme	support	1014:1020	arg1	surface					999:1005	the surface	995:1005	the surface of the support	995:1020	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	3	70	theme	@	769:769	arg1	SA					770:771	the R. palustris/CAT@SA	749:771	the R. palustris/CAT@SA	749:771	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	2	71	dep	nanotube	564:571	arg1	CAT					648:650	CAT	648:650	CAT	648:650	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	71	dep	nanotube	564:571	arg1	composite					623:631	photocatalytic composite	608:631	photocatalytic composite	608:631	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	2	71	dep	nanotube	564:571	arg1	-TiO2					641:645	CNT-Ag -TiO2	634:645	CNT-Ag -TiO2	634:645	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	4	72	theme	red	949:951	arg1	degradation					928:938	the degradation	924:938	the degradation of Congo red by the new ICPB	924:967	The mechanism of the degradation of Congo red by the new ICPB was that the Congo red on the surface of the support was degraded into long-chain alkanes by the superoxide and hydroxyl radicals of CAT product, and then the long-chain alkanes were completely mineralization by R. Palustris, which reduced the accumulation of intermediates in the photocatalysis.					
35351474	5	73	dep	carrier	1324:1330	arg1	degraded					1336:1343	degraded	1336:1343	was degraded into aromatic hydrocarbons by R. Palustris	1332:1386	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	5	73	dep	carrier	1324:1330	arg1	oxidized					1398:1405	oxidized	1398:1405	oxidized	1398:1405	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	2	74	theme	degradation	366:376	arg1	efficiency					378:387	the degradation efficiency	362:387	the degradation efficiency of Congo red wastewater	362:411	In order to improve the degradation efficiency of Congo red wastewater, A novel intimately coupled photocatalysis and biodegradation (ICPB) system was prepared by coupling Rhodopseudomonas palustris (R. Palustris), carbon nanotube - silver modified titanium dioxide photocatalytic composite (CNT-Ag -TiO2, CAT) and sodium alginate (SA) (R. palustris/CAT@SA).					
35351474	3	75	theme	removal	802:808	arg1	rates					810:814	the degradation and removal rates	782:814	rates	810:814	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35351474	5	76	theme	small	1434:1438	arg1	part					1440:1443	a small part	1432:1443	a small part of the Congo red	1432:1460	Most of the Congo red was adsorbed to the interior of the carrier was degraded into aromatic hydrocarbons by R. Palustris, and then oxidized and degraded by CAT, and a small part of the Congo red would be directly mineralized by R. Palustris.					
35351474	3	77	theme	R.	753:754	arg1	SA					770:771	the R. palustris/CAT@SA	749:771	the R. palustris/CAT@SA	749:771	Compared with immobilized CAT and R. palustris, the R. palustris/CAT@SA improved the degradation and removal rates of Congo red by 14.3% and 42.1%, and the COD removal rates by 76% and 44.6%, respectively.					
35590481	14	0	theme	texture	2272:2278	arg1	quality					2280:2286	the texture quality	2268:2286	the texture quality of FMP	2268:2293	Compared to TP treatment, HPP could effectively improve the texture quality of FMP by inhibiting pectin degradation during storage.					
35590481	11	1	theme	effective	1683:1691	arg1	HPP					1672:1674	HPP	1672:1674	HPP	1672:1674	Hence, HPP was an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage.					
35590481	11	1	theme	effective	1683:1691	arg1	method					1693:1698	an effective method	1680:1698	an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage	1680:1789	Hence, HPP was an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage.					
35590481	4	2	theme	cell	555:558	arg1	material					565:572	cell wall material	555:572	cell wall material (CWM)	555:578	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	2	theme	cell	555:558	arg1	CWM					575:577	CWM	575:577	CWM	575:577	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	9	3	dep	extremely	1466:1474	arg1	p < 0.01					1477:1484	p < 0.01	1477:1484	p < 0.01	1477:1484	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	3	4	theme	TP	498:499	arg1	treatments					501:510	HPP and TP treatments	490:510	HPP and TP treatments	490:510	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	15	5	theme	new	2407:2409	arg1	insights					2411:2418	new insights	2407:2418	new insights into regulating the texture quality of FMP	2407:2461	All the findings presented in this study would help to provide new insights into regulating the texture quality of FMP.					
35590481	5	6	theme	HPP-treated	778:788	arg1	FMP					790:792	HPP-treated FMP	778:792	HPP-treated FMP	778:792	HPP-treated FMP showed higher hardness (66.64-85.95 N) than that in TP-treated one (57.23-62.72 N) during storage.					
35590481	12	7	theme	PRACTICAL	1792:1800	arg1	APPLICATION					1802:1812	PRACTICAL APPLICATION	1792:1812	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.	1792:1985	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	7	8	from	ratio	1106:1110	arg1	pectins					1144:1150	three pectins	1138:1150	three pectins	1138:1150	However, the molar ratio of most monosaccharide in three pectins decreased after storage.					
35590481	10	9	theme	CSP	1618:1620	arg1	Mw					1622:1623	CSP Mw	1618:1623	CSP Mw	1618:1623	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	1	10	theme	fermentation	196:207	arg1	acceptance					182:191	the sensory and market acceptance	159:191	the sensory and market acceptance of fermentation minced pepper (FMP)	159:227	Texture quality affects the sensory and market acceptance of fermentation minced pepper (FMP), but it will deteriorate during storage.					
35590481	6	11	dep	reached	1033:1039	arg1	compositions					958:969	the crucial compositions	946:969	the crucial compositions	946:969	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	2	12	theme	pressure	281:288	arg1	processing					290:299	high pressure processing	276:299	high pressure processing (HPP)	276:305	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	2	12	theme	pressure	281:288	arg1	HPP					302:304	HPP	302:304	HPP	302:304	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	8	13	theme	most	1295:1298	arg1	components					1307:1316	most pectin components	1295:1316	most pectin components	1295:1316	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	4	14	theme	carbonate-soluble	591:607	arg1	SSP					617:619	SSP	617:619	SSP	617:619	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	14	theme	carbonate-soluble	591:607	arg1	pectin					609:614	sodium carbonate-soluble pectin	584:614	sodium carbonate-soluble pectin (SSP)	584:620	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	10	15	theme	lower	1631:1635	arg1	content					1641:1647	lower WSP content	1631:1647	lower WSP content	1631:1647	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	9	16	theme	correlation	1342:1352	arg1	analysis					1354:1361	Pearson correlation analysis	1334:1361	Pearson correlation analysis	1334:1361	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	13	17	theme	HPP-	2039:2042	arg1	FMP					2059:2061	HPP- and TP-treated FMP	2039:2061	HPP- and TP-treated FMP during storage	2039:2076	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	4	18	theme	WSP	653:655	arg1	Mw					676:677	Mw	676:677	Mw	676:677	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	18	theme	WSP	653:655	arg1	weight					668:673	water-soluble pectin (WSP) molecular weight	631:673	water-soluble pectin (WSP) molecular weight (Mw )	631:679	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	18	theme	WSP	653:655	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	19	theme	molecular	658:666	arg1	Mw					676:677	Mw	676:677	Mw	676:677	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	19	theme	molecular	658:666	arg1	weight					668:673	water-soluble pectin (WSP) molecular weight	631:673	water-soluble pectin (WSP) molecular weight (Mw )	631:679	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	19	theme	molecular	658:666	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	10	20	theme	Rha	1605:1607	arg1	content					1609:1615	Rha content	1605:1615	Rha content	1605:1615	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	1	21	theme	Texture	135:141	arg1	quality					143:149	Texture quality	135:149	Texture quality	135:149	Texture quality affects the sensory and market acceptance of fermentation minced pepper (FMP), but it will deteriorate during storage.					
35590481	0	22	theme	fermented	57:65	arg1	pepper					74:79	fermented minced pepper	57:79	fermented minced pepper	57:79	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	4	23	theme	pectin	645:650	arg1	Mw					676:677	Mw	676:677	Mw	676:677	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	23	theme	pectin	645:650	arg1	weight					668:673	water-soluble pectin (WSP) molecular weight	631:673	water-soluble pectin (WSP) molecular weight (Mw )	631:679	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	23	theme	pectin	645:650	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	0	24	theme	pepper	74:79	arg1	quality					46:52	the texture quality	34:52	the texture quality of fermented minced pepper	34:79	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	8	25	theme	force	1184:1188	arg1	images					1201:1206	Atomic force microscope images	1177:1206	Atomic force microscope images	1177:1206	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	9	26	dep	extremely	1393:1401	arg1	p < 0.01					1404:1411	p < 0.01	1404:1411	p < 0.01	1404:1411	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	4	27	theme	WSP	698:700	arg1	content					702:708	WSP content	698:708	WSP content	698:708	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	11	28	theme	texture	1715:1721	arg1	quality					1723:1729	the texture quality	1711:1729	the texture quality of FMP	1711:1736	Hence, HPP was an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage.					
35590481	15	29	theme	texture	2440:2446	arg1	quality					2448:2454	the texture quality	2436:2454	the texture quality of FMP	2436:2461	All the findings presented in this study would help to provide new insights into regulating the texture quality of FMP.					
35590481	3	30	theme	HPP	490:492	arg1	treatments					501:510	HPP and TP treatments	490:510	HPP and TP treatments	490:510	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	0	31	theme	High	0:3	arg1	processing					14:23	High pressure processing	0:23	High pressure processing	0:23	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	5	32	theme	TP-treated	846:855	arg1	one					857:859	TP-treated one	846:859	TP-treated one (57.23-62.72 N) during storage	846:890	HPP-treated FMP showed higher hardness (66.64-85.95 N) than that in TP-treated one (57.23-62.72 N) during storage.					
35590481	5	32	theme	TP-treated	846:855	arg1	N					874:874	57.23-62.72 N	862:874	57.23-62.72 N	862:874	HPP-treated FMP showed higher hardness (66.64-85.95 N) than that in TP-treated one (57.23-62.72 N) during storage.					
35590481	5	33	dep	higher	801:806	arg1	hardness					808:815	hardness	808:815	hardness (66.64-85.95 N)	808:831	HPP-treated FMP showed higher hardness (66.64-85.95 N) than that in TP-treated one (57.23-62.72 N) during storage.					
35590481	5	33	dep	higher	801:806	arg1	N					830:830	66.64-85.95 N	818:830	66.64-85.95 N	818:830	HPP-treated FMP showed higher hardness (66.64-85.95 N) than that in TP-treated one (57.23-62.72 N) during storage.					
35590481	2	34	theme	FMP	383:385	arg1	quality					372:378	the texture quality	360:378	the texture quality of FMP	360:385	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	8	35	theme	branch	1239:1244	arg1	structures					1246:1255	branch structures	1239:1255	branch structures	1239:1255	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	1	36	theme	market	175:180	arg1	acceptance					182:191	the sensory and market acceptance	159:191	the sensory and market acceptance of fermentation minced pepper (FMP)	159:227	Texture quality affects the sensory and market acceptance of fermentation minced pepper (FMP), but it will deteriorate during storage.					
35590481	13	37	theme	quality	2006:2012	arg1	Changes					1987:1993	Changes	1987:1993	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage	1987:2076	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	CSP					2207:2209	CSP	2207:2209	CSP	2207:2209	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	compositions					2141:2152	monosaccharide compositions	2126:2152	monosaccharide compositions	2126:2152	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	SSP					2198:2200	SSP	2198:2200	SSP	2198:2200	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	content					2117:2123	content	2117:2123	content	2117:2123	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	distribution					2158:2169	Mw distribution	2155:2169	Mw distribution	2155:2169	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	nanostructure					2176:2188	nanostructure	2176:2188	nanostructure	2176:2188	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	13	38	theme	WSP	2193:2195	arg1	hardness					2103:2110	hardness	2103:2110	hardness	2103:2110	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	14	39	theme	TP	2224:2225	arg1	treatment					2227:2235	TP treatment	2224:2235	TP treatment	2224:2235	Compared to TP treatment, HPP could effectively improve the texture quality of FMP by inhibiting pectin degradation during storage.					
35590481	10	40	theme	higher	1567:1572	arg1	hardness					1574:1581	higher hardness	1567:1581	higher hardness	1567:1581	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	13	41	theme	pectin	2018:2023	arg1	properties					2025:2034	pectin properties	2018:2034	pectin properties	2018:2034	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	7	42	theme	most	1115:1118	arg1	monosaccharide					1120:1133	most monosaccharide	1115:1133	most monosaccharide	1115:1133	However, the molar ratio of most monosaccharide in three pectins decreased after storage.					
35590481	13	43	dep	content	2117:2123	arg1	the					2113:2115	the	2113:2115	the	2113:2115	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	3	44	from	variations	427:436	arg1	quality					449:455	texture quality and pectin characteristics	441:482	quality	449:455	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	3	44	from	variations	427:436	arg1	characteristics					468:482	texture quality and pectin characteristics	441:482	characteristics	468:482	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	14	45	theme	FMP	2291:2293	arg1	quality					2280:2286	the texture quality	2268:2286	the texture quality of FMP	2268:2293	Compared to TP treatment, HPP could effectively improve the texture quality of FMP by inhibiting pectin degradation during storage.					
35590481	4	46	theme	wall	560:563	arg1	material					565:572	cell wall material	555:572	cell wall material (CWM)	555:578	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	46	theme	wall	560:563	arg1	CWM					575:577	CWM	575:577	CWM	575:577	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	11	47	theme	FMP	1734:1736	arg1	quality					1723:1729	the texture quality	1711:1729	the texture quality of FMP	1711:1736	Hence, HPP was an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage.					
35590481	12	48	theme	pectin	1979:1984	arg1	depolymerization					1959:1974	depolymerization	1959:1974	depolymerization	1959:1974	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	12	48	theme	pectin	1979:1984	arg1	modification					1942:1953	modification	1942:1953	modification	1942:1953	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	3	49	theme	pectin	461:466	arg1	characteristics					468:482	texture quality and pectin characteristics	441:482	characteristics	468:482	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	12	50	theme	factors	1844:1850	arg1	one					1828:1830	one	1828:1830	one	1828:1830	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	12	50	theme	factors	1844:1850	arg1	factors					1844:1850	the main factors	1835:1850	the main factors affecting market value and consumer preferences for FMP	1835:1906	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	9	51	theme	WSP	1514:1516	arg1	content					1518:1524	WSP content	1514:1524	WSP content	1514:1524	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	2	52	theme	high	276:279	arg1	pressure					281:288	high pressure	276:288	high pressure processing (HPP)	276:305	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	12	53	theme	consumer	1879:1886	arg1	preferences					1888:1898	consumer preferences	1879:1898	consumer preferences	1879:1898	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	13	54	theme	monosaccharide	2126:2139	arg1	compositions					2141:2152	monosaccharide compositions	2126:2152	monosaccharide compositions	2126:2152	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	4	55	theme	pectin	609:614	arg1	content					622:628	cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content	555:628	cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content	555:628	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	55	theme	pectin	609:614	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	8	56	theme	pectin	1300:1305	arg1	components					1307:1316	most pectin components	1295:1316	most pectin components	1295:1316	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	6	57	theme	molar	1005:1009	arg1	ratios					1011:1016	their total molar ratios	993:1016	their total molar ratios	993:1016	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	10	58	theme	WSP	1637:1639	arg1	content					1641:1647	lower WSP content	1631:1647	lower WSP content	1631:1647	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	13	59	theme	Mw	2155:2156	arg1	distribution					2158:2169	Mw distribution	2155:2169	Mw distribution	2155:2169	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	9	60	theme	Pearson	1334:1340	arg1	analysis					1354:1361	Pearson correlation analysis	1334:1361	Pearson correlation analysis	1334:1361	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	6	61	theme	TP	1073:1074	arg1	treatment					1076:1084	HPP and TP treatment	1065:1084	treatment	1076:1084	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	4	62	theme	sodium	584:589	arg1	SSP					617:619	SSP	617:619	SSP	617:619	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	62	theme	sodium	584:589	arg1	pectin					609:614	sodium carbonate-soluble pectin	584:614	sodium carbonate-soluble pectin (SSP)	584:620	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	11	63	theme	pectin	1753:1758	arg1	characteristics					1760:1774	pectin characteristics	1753:1774	pectin characteristics	1753:1774	Hence, HPP was an effective method to improve the texture quality of FMP by maintaining pectin characteristics during storage.					
35590481	6	64	theme	HPP	1065:1067	arg1	treatment					1076:1084	HPP and TP treatment	1065:1084	treatment	1076:1084	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	9	65	theme	FMP	1376:1378	arg1	hardness					1380:1387	FMP hardness	1376:1387	FMP hardness	1376:1387	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	2	66	used	used	344:347	arg2	HPP					302:304	HPP	302:304	HPP	302:304	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	2	66	used	used	344:347	arg2	processing					290:299	high pressure processing	276:299	high pressure processing (HPP)	276:305	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	2	66	used	used	344:347	arg2	pasteurization					319:332	thermal pasteurization	311:332	thermal pasteurization (TP)	311:337	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	2	66	used	used	344:347	arg2	TP					335:336	TP	335:336	TP	335:336	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	0	67	theme	minced	67:72	arg1	pepper					74:79	fermented minced pepper	57:79	fermented minced pepper	57:79	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	12	68	theme	market	1862:1867	arg1	value					1869:1873	market value	1862:1873	market value	1862:1873	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	15	69	theme	FMP	2459:2461	arg1	quality					2448:2454	the texture quality	2436:2454	the texture quality of FMP	2436:2461	All the findings presented in this study would help to provide new insights into regulating the texture quality of FMP.					
35590481	13	70	from	Changes	1987:1993	arg1	FMP					2059:2061	HPP- and TP-treated FMP	2039:2061	HPP- and TP-treated FMP during storage	2039:2076	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	1	71	theme	sensory	163:169	arg1	acceptance					182:191	the sensory and market acceptance	159:191	the sensory and market acceptance of fermentation minced pepper (FMP)	159:227	Texture quality affects the sensory and market acceptance of fermentation minced pepper (FMP), but it will deteriorate during storage.					
35590481	4	72	theme	water-soluble	631:643	arg1	Mw					676:677	Mw	676:677	Mw	676:677	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	72	theme	water-soluble	631:643	arg1	weight					668:673	water-soluble pectin (WSP) molecular weight	631:673	water-soluble pectin (WSP) molecular weight (Mw )	631:679	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	72	theme	water-soluble	631:643	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	0	73	theme	pectin	96:101	arg1	characteristics					103:117	pectin characteristics	96:117	pectin characteristics	96:117	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	8	74	theme	Atomic	1177:1182	arg1	images					1201:1206	Atomic force microscope images	1177:1206	Atomic force microscope images	1177:1206	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	6	75	theme	crucial	950:956	arg1	compositions					958:969	the crucial compositions	946:969	the crucial compositions	946:969	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	12	76	dep	APPLICATION	1802:1812	arg1	one					1828:1830	one	1828:1830	one	1828:1830	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	12	76	dep	APPLICATION	1802:1812	arg1	factors					1844:1850	the main factors	1835:1850	the main factors affecting market value and consumer preferences for FMP	1835:1906	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	12	76	dep	APPLICATION	1802:1812	arg1	related					1927:1933	related	1927:1933	related	1927:1933	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	9	77	dep	demonstrated	1363:1374	arg1	correlated					1425:1434	correlated	1425:1434	was extremely (p < 0.01) positively correlated with CWM and SSP content	1389:1459	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	9	77	dep	demonstrated	1363:1374	arg1	correlated					1498:1507	correlated	1498:1507	negatively correlated with WSP content	1487:1524	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	0	78	theme	pressure	5:12	arg1	processing					14:23	High pressure processing	0:23	High pressure processing	0:23	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	4	79	theme	chelate-soluble	721:735	arg1	Mw					750:751	sodium chelate-soluble pectin (CSP) Mw	714:751	sodium chelate-soluble pectin (CSP) Mw	714:751	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	9	80	theme	SSP	1449:1451	arg1	content					1453:1459	SSP content	1449:1459	SSP content	1449:1459	Pearson correlation analysis demonstrated FMP hardness was extremely (p < 0.01) positively correlated with CWM and SSP content, and extremely (p < 0.01) negatively correlated with WSP content.					
35590481	8	81	theme	short	1222:1226	arg1	chains					1228:1233	the short chains	1218:1233	the short chains	1218:1233	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	10	82	theme	TP	1539:1540	arg1	treatment					1542:1550	TP treatment	1539:1550	TP treatment	1539:1550	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	0	83	theme	texture	38:44	arg1	quality					46:52	the texture quality	34:52	the texture quality of fermented minced pepper	34:79	High pressure processing improves the texture quality of fermented minced pepper by maintaining pectin characteristics during storage.					
35590481	13	84	theme	TP-treated	2048:2057	arg1	FMP					2059:2061	HPP- and TP-treated FMP	2039:2061	HPP- and TP-treated FMP during storage	2039:2076	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	7	85	theme	monosaccharide	1120:1133	arg1	ratio					1106:1110	the molar ratio	1096:1110	the molar ratio of most monosaccharide in three pectins	1096:1150	However, the molar ratio of most monosaccharide in three pectins decreased after storage.					
35590481	4	86	theme	pectin	737:742	arg1	Mw					750:751	sodium chelate-soluble pectin (CSP) Mw	714:751	sodium chelate-soluble pectin (CSP) Mw	714:751	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	2	87	theme	texture	364:370	arg1	quality					372:378	the texture quality	360:378	the texture quality of FMP	360:385	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	14	88	theme	pectin	2309:2314	arg1	degradation					2316:2326	pectin degradation	2309:2326	pectin degradation	2309:2326	Compared to TP treatment, HPP could effectively improve the texture quality of FMP by inhibiting pectin degradation during storage.					
35590481	6	89	theme	total	999:1003	arg1	ratios					1011:1016	their total molar ratios	993:1016	their total molar ratios	993:1016	Rhamnose (Rha), arabinose, mannose, and glucose were the crucial compositions in three pectins, and their total molar ratios, respectively, reached 89.19% and 87.97% after HPP and TP treatment.					
35590481	4	90	theme	CSP	745:747	arg1	Mw					750:751	sodium chelate-soluble pectin (CSP) Mw	714:751	sodium chelate-soluble pectin (CSP) Mw	714:751	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	2	91	theme	thermal	311:317	arg1	TP					335:336	TP	335:336	TP	335:336	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	2	91	theme	thermal	311:317	arg1	pasteurization					319:332	thermal pasteurization	311:332	thermal pasteurization (TP)	311:337	Thus, high pressure processing (HPP) and thermal pasteurization (TP) were used to improve the texture quality of FMP during storage.					
35590481	13	92	theme	properties	2025:2034	arg1	Changes					1987:1993	Changes	1987:1993	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage	1987:2076	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
35590481	12	93	dep	modification	1942:1953	arg1	the					1938:1940	the	1938:1940	the	1938:1940	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	7	94	theme	molar	1100:1104	arg1	ratio					1106:1110	the molar ratio	1096:1110	the molar ratio of most monosaccharide in three pectins	1096:1150	However, the molar ratio of most monosaccharide in three pectins decreased after storage.					
35590481	4	95	theme	material	565:572	arg1	content					622:628	cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content	555:628	cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content	555:628	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	4	95	theme	material	565:572	arg1	hardness					545:552	The hardness	541:552	The hardness	541:552	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	8	96	theme	microscope	1190:1199	arg1	images					1201:1206	Atomic force microscope images	1177:1206	Atomic force microscope images	1177:1206	Atomic force microscope images indicated the short chains and branch structures increased but aggregates decreased in most pectin components during storage.					
35590481	3	97	theme	texture	441:447	arg1	quality					449:455	texture quality and pectin characteristics	441:482	quality	449:455	The results showed that variations in texture quality and pectin characteristics under HPP and TP treatments were similar during storage.					
35590481	12	98	theme	main	1839:1842	arg1	factors					1844:1850	the main factors	1835:1850	the main factors affecting market value and consumer preferences for FMP	1835:1906	PRACTICAL APPLICATION: Softening is one of the main factors affecting market value and consumer preferences for FMP, and it is closely related to the modification and depolymerization of pectin.					
35590481	4	99	theme	sodium	714:719	arg1	Mw					750:751	sodium chelate-soluble pectin (CSP) Mw	714:751	sodium chelate-soluble pectin (CSP) Mw	714:751	The hardness, cell wall material (CWM) and sodium carbonate-soluble pectin (SSP) content, water-soluble pectin (WSP) molecular weight (Mw ) decreased, while WSP content and sodium chelate-soluble pectin (CSP) Mw increased after storage.					
35590481	10	100	theme	SSP	1584:1586	arg1	content					1588:1594	SSP content	1584:1594	SSP content	1584:1594	Compared to TP treatment, HPP presented higher hardness, SSP content and Mw , Rha content, CSP Mw , and lower WSP content during storage.					
35590481	13	101	theme	texture	1998:2004	arg1	quality					2006:2012	texture quality	1998:2012	texture quality	1998:2012	Changes of texture quality and pectin properties in HPP- and TP-treated FMP during storage were assessed, including hardness, the content, monosaccharide compositions, Mw distribution, and nanostructure of WSP, SSP, and CSP.					
36441188	1	0	from	release	197:203	arg1	region					242:247	the colonic inflammatory region	217:247	the colonic inflammatory region	217:247	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	2	1	theme	anti-inflammatory	356:372	arg1	drug					374:377	synergistic anti-inflammatory drug	344:377	synergistic anti-inflammatory drug	344:377	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	1	2	from	accumulation	170:181	arg1	region					242:247	the colonic inflammatory region	217:247	the colonic inflammatory region	217:247	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	2	3	theme	synergistic	344:354	arg1	drug					374:377	synergistic anti-inflammatory drug	344:377	synergistic anti-inflammatory drug	344:377	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	3	4	theme	encapsulation	528:540	arg1	efficiency					542:551	The encapsulation efficiency	524:551	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles	524:607	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	3	5	theme	quercetin	556:564	arg1	efficiency					542:551	The encapsulation efficiency	524:551	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles	524:607	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	0	6	theme	Quercetin	91:99	arg1	Co-Delivery					76:86	Co-Delivery	76:86	Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment	76:163	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	6	7	theme	Que-HQP-EGCG-CLRS	980:996	arg1	micelles					998:1005	the Que-HQP-EGCG-CLRS micelles	976:1005	the Que-HQP-EGCG-CLRS micelles	976:1005	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	1	8	theme	ulcerative	289:298	arg1	UC					309:310	UC	309:310	UC	309:310	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	8	theme	ulcerative	289:298	arg1	colitis					300:306	ulcerative colitis	289:306	ulcerative colitis (UC)	289:311	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	9	theme	3-Gallate	123:131	arg1	Co-Delivery					76:86	Co-Delivery	76:86	Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment	76:163	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	7	10	theme	colonic	1255:1261	arg1	effect					1288:1293	colonic inflammatory-accumulated effect	1255:1293	colonic inflammatory-accumulated effect	1255:1293	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	6	11	theme	drugs	1101:1105	arg1	release					1090:1096	sustained release	1080:1096	sustained release of drugs (more than 24 h)	1080:1122	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	6	12	theme	UC	1166:1167	arg1	symptoms					1154:1161	the symptoms	1150:1161	the symptoms of UC	1150:1167	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	1	13	theme	sustained	187:195	arg1	accumulation					170:181	accumulation	170:181	accumulation	170:181	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	13	theme	sustained	187:195	arg1	release					197:203	sustained release	187:203	sustained release	187:203	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	13	theme	sustained	187:195	arg1	strategy					267:274	the favorable strategy	253:274	the favorable strategy for treating ulcerative colitis (UC)	253:311	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	14	theme	Epigallo-catechin	105:121	arg1	3-Gallate					123:131	Epigallo-catechin 3-Gallate	105:131	Epigallo-catechin 3-Gallate	105:131	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	2	15	theme	hydrolytic	417:426	arg1	HQP					444:446	HQP	444:446	HQP	444:446	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	15	theme	hydrolytic	417:426	arg1	protein					435:441	hydrolytic quinoa protein	417:441	hydrolytic quinoa protein (HQP)	417:447	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	5	16	dep	in	782:783	arg1	vitro					785:789	vitro	785:789	vitro	785:789	Moreover, the in vitro experiments indicated that these micelles can make Que/EGCG pass through gastric environments stably and delay their release in the intestine.					
36441188	2	17	theme	-loaded	395:401	arg1	micelle					403:409	a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle	342:409	a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS)	342:485	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	0	18	theme	Quinoa	11:16	arg1	Protein					18:24	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Protein	18:24	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	6	19	theme	inflammatory	1049:1060	arg1	region					1062:1067	the colonic inflammatory region	1037:1067	the colonic inflammatory region	1037:1067	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	7	20	theme	drug	1310:1313	arg1	release					1315:1321	sustained drug release	1300:1321	sustained drug release	1300:1321	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	21	theme	good	1231:1234	arg1	stability					1244:1252	good gastric stability	1231:1252	good gastric stability	1231:1252	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	1	22	dep	accumulation	170:181	arg1	The					166:168	The	166:168	The	166:168	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	23	theme	Hydrolytic	0:9	arg1	Protein					18:24	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Protein	18:24	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	4	24	theme	composite	652:660	arg1	micelle					662:668	This composite micelle	647:668	This composite micelle	647:668	This composite micelle exhibited a core-shell structure, where Que-HQP-EGCG was the core and CLRS was the coating shell.					
36441188	3	25	theme	EGCG	570:573	arg1	efficiency					542:551	The encapsulation efficiency	524:551	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles	524:607	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	4	26	theme	coating	753:759	arg1	CLRS					740:743	CLRS	740:743	CLRS	740:743	This composite micelle exhibited a core-shell structure, where Que-HQP-EGCG was the core and CLRS was the coating shell.					
36441188	4	26	theme	coating	753:759	arg1	shell					761:765	the coating shell	749:765	the coating shell	749:765	This composite micelle exhibited a core-shell structure, where Que-HQP-EGCG was the core and CLRS was the coating shell.					
36441188	1	27	theme	drugs	208:212	arg1	accumulation					170:181	accumulation	170:181	accumulation	170:181	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	27	theme	drugs	208:212	arg1	release					197:203	sustained release	187:203	sustained release	187:203	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	27	theme	drugs	208:212	arg1	strategy					267:274	the favorable strategy	253:274	the favorable strategy for treating ulcerative colitis (UC)	253:311	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	28	theme	Ulcerative	136:145	arg1	Colitis					147:153	Ulcerative Colitis	136:153	Ulcerative Colitis Treatment	136:163	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	5	29	from	release	908:914	arg1	intestine					923:931	the intestine	919:931	the intestine	919:931	Moreover, the in vitro experiments indicated that these micelles can make Que/EGCG pass through gastric environments stably and delay their release in the intestine.					
36441188	2	30	theme	root	468:471	arg1	CLRS					481:484	CLRS	481:484	CLRS	481:484	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	30	theme	root	468:471	arg1	starch					473:478	cationic lotus root starch	453:478	cationic lotus root starch (CLRS)	453:485	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	31	theme	quinoa	428:433	arg1	HQP					444:446	HQP	444:446	HQP	444:446	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	31	theme	quinoa	428:433	arg1	protein					435:441	hydrolytic quinoa protein	417:441	hydrolytic quinoa protein (HQP)	417:447	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	0	32	theme	Lotus	39:43	arg1	Micelles					63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Micelles	63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	0	33	from	Co-Delivery	76:86	arg1	Treatment					155:163	Ulcerative Colitis Treatment	136:163	Ulcerative Colitis Treatment	136:163	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	3	34	theme	Que-HQP-EGCG-CLRS	582:598	arg1	micelles					600:607	the Que-HQP-EGCG-CLRS micelles	578:607	the Que-HQP-EGCG-CLRS micelles	578:607	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	5	35	theme	gastric	864:870	arg1	environments					872:883	gastric environments	864:883	gastric environments	864:883	Moreover, the in vitro experiments indicated that these micelles can make Que/EGCG pass through gastric environments stably and delay their release in the intestine.					
36441188	1	36	theme	colonic	221:227	arg1	region					242:247	the colonic inflammatory region	217:247	the colonic inflammatory region	217:247	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	37	theme	Cationic	30:37	arg1	Micelles					63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Micelles	63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	0	38	theme	Colitis	147:153	arg1	Treatment					155:163	Ulcerative Colitis Treatment	136:163	Ulcerative Colitis Treatment	136:163	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	1	39	theme	inflammatory	229:240	arg1	region					242:247	the colonic inflammatory region	217:247	the colonic inflammatory region	217:247	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	0	40	theme	Starch-Based	50:61	arg1	Micelles					63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Micelles	63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	6	41	theme	Animal	934:939	arg1	experiments					941:951	Animal experiments	934:951	Animal experiments	934:951	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	5	42	theme	in	782:783	arg1	experiments					791:801	the in vitro experiments	778:801	the in vitro experiments	778:801	Moreover, the in vitro experiments indicated that these micelles can make Que/EGCG pass through gastric environments stably and delay their release in the intestine.					
36441188	7	43	theme	gastric	1236:1242	arg1	stability					1244:1252	good gastric stability	1231:1252	good gastric stability	1231:1252	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	2	44	theme	assembly	507:514	arg1	method					516:521	a layer-by-layer assembly method	490:521	a layer-by-layer assembly method	490:521	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	0	45	theme	Root	45:48	arg1	Micelles					63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles	0:70	Micelles	63:70	Hydrolytic Quinoa Protein and Cationic Lotus Root Starch-Based Micelles for Co-Delivery of Quercetin and Epigallo-catechin 3-Gallate in Ulcerative Colitis Treatment.					
36441188	6	46	theme	sustained	1080:1088	arg1	release					1090:1096	sustained release	1080:1096	sustained release of drugs (more than 24 h)	1080:1122	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	2	47	theme	cationic	453:460	arg1	CLRS					481:484	CLRS	481:484	CLRS	481:484	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	47	theme	cationic	453:460	arg1	starch					473:478	cationic lotus root starch	453:478	cationic lotus root starch (CLRS)	453:485	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	7	48	theme	Que-HQP-EGCG-CLRS	1199:1215	arg1	micelles					1217:1224	Que-HQP-EGCG-CLRS micelles	1199:1224	Que-HQP-EGCG-CLRS micelles	1199:1224	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	49	theme	sustained	1300:1308	arg1	release					1315:1321	sustained drug release	1300:1321	sustained drug release	1300:1321	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	3	50	theme	91.5	617:620	arg1	%					630:630	91.5 and 89.4%	617:630	%	630:630	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	7	51	contain	have	1226:1229	arg2	system					1366:1371	a promising co-delivery system	1342:1371	a promising co-delivery system for UC treatment	1342:1388	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	51	contain	have	1226:1229	arg1	micelles					1217:1224	Que-HQP-EGCG-CLRS micelles	1199:1224	Que-HQP-EGCG-CLRS micelles	1199:1224	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	51	contain	have	1226:1229	arg2	ability					1323:1329	ability	1323:1329	ability	1323:1329	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	6	52	theme	colonic	1041:1047	arg1	region					1062:1067	the colonic inflammatory region	1037:1067	the colonic inflammatory region	1037:1067	Animal experiments further confirmed that the Que-HQP-EGCG-CLRS micelles can efficiently accumulate in the colonic inflammatory region and enable sustained release of drugs (more than 24 h), thus notably alleviating the symptoms of UC.					
36441188	3	53	theme	89.4	626:629	arg1	%					630:630	91.5 and 89.4%	617:630	%	630:630	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	5	54	theme	Que/EGCG	842:849	arg1	pass					851:854	Que/EGCG pass	842:854	Que/EGCG pass	842:854	Moreover, the in vitro experiments indicated that these micelles can make Que/EGCG pass through gastric environments stably and delay their release in the intestine.					
36441188	2	55	theme	layer-by-layer	492:505	arg1	method					516:521	a layer-by-layer assembly method	490:521	a layer-by-layer assembly method	490:521	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	3	56	from	efficiency	542:551	arg1	micelles					600:607	the Que-HQP-EGCG-CLRS micelles	578:607	the Que-HQP-EGCG-CLRS micelles	578:607	The encapsulation efficiency of quercetin and EGCG in the Que-HQP-EGCG-CLRS micelles reached 91.5 and 89.4%, respectively.					
36441188	7	57	theme	co-delivery	1354:1364	arg1	ability					1323:1329	ability	1323:1329	ability	1323:1329	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	57	theme	co-delivery	1354:1364	arg1	system					1366:1371	a promising co-delivery system	1342:1371	a promising co-delivery system for UC treatment	1342:1388	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	4	58	theme	core-shell	682:691	arg1	structure					693:701	a core-shell structure	680:701	a core-shell structure	680:701	This composite micelle exhibited a core-shell structure, where Que-HQP-EGCG was the core and CLRS was the coating shell.					
36441188	7	59	theme	promising	1344:1352	arg1	ability					1323:1329	ability	1323:1329	ability	1323:1329	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	7	59	theme	promising	1344:1352	arg1	system					1366:1371	a promising co-delivery system	1342:1371	a promising co-delivery system for UC treatment	1342:1388	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	2	60	theme	lotus	462:466	arg1	CLRS					481:484	CLRS	481:484	CLRS	481:484	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	60	theme	lotus	462:466	arg1	starch					473:478	cationic lotus root starch	453:478	cationic lotus root starch (CLRS)	453:485	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	2	61	dep	-loaded	395:401	arg1	drug					374:377	synergistic anti-inflammatory drug	344:377	synergistic anti-inflammatory drug	344:377	In this study, we developed a synergistic anti-inflammatory drug (quercetin/EGCG)-loaded micelle using hydrolytic quinoa protein (HQP) and cationic lotus root starch (CLRS) by a layer-by-layer assembly method.					
36441188	7	62	theme	inflammatory-accumulated	1263:1286	arg1	effect					1288:1293	colonic inflammatory-accumulated effect	1255:1293	colonic inflammatory-accumulated effect	1255:1293	These results suggested that Que-HQP-EGCG-CLRS micelles have good gastric stability, colonic inflammatory-accumulated effect, and sustained drug release ability, which are a promising co-delivery system for UC treatment.					
36441188	1	63	theme	favorable	257:265	arg1	accumulation					170:181	accumulation	170:181	accumulation	170:181	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	63	theme	favorable	257:265	arg1	release					197:203	sustained release	187:203	sustained release	187:203	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
36441188	1	63	theme	favorable	257:265	arg1	strategy					267:274	the favorable strategy	253:274	the favorable strategy for treating ulcerative colitis (UC)	253:311	The accumulation and sustained release of drugs in the colonic inflammatory region are the favorable strategy for treating ulcerative colitis (UC).					
35349993	6	0	theme	@	1010:1010	arg1	IBU					1011:1013	CL-CD-MOF@IBU	1001:1013	CL-CD-MOF@IBU	1001:1013	CL-CD-MOF@IBU was prepared by immersing CL-CD-MOF in high-concentration ibuprofen (IBU) solution.					
35349993	11	1	with	co-culture	1658:1667	arg1	cells					1683:1687	MC3T3-E1 cells	1674:1687	MC3T3-E1 cells	1674:1687	G-GH/CL-CD-MOF@IBU exhibited good biocompatibility during co-culture with MC3T3-E1 cells.					
35349993	7	2	theme	hydrogel	1206:1213	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	11	3	theme	@	1614:1614	arg1	IBU					1615:1617	G-GH/CL-CD-MOF@IBU	1600:1617	G-GH/CL-CD-MOF@IBU	1600:1617	G-GH/CL-CD-MOF@IBU exhibited good biocompatibility during co-culture with MC3T3-E1 cells.					
35349993	7	4	theme	IBU	1192:1194	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	8	5	theme	compression	1261:1271	arg1	curve					1273:1277	The compression curve	1257:1277	The compression curve of G-GH/CL-CD-MOF composite hydrogel	1257:1314	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	12	6	theme	potential	1853:1861	arg1	application					1863:1873	potential application	1853:1873	potential application	1853:1873	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	7	theme	°C.	716:718	arg1	CL-CD-MOF					720:728	37 °C. CL-CD-MOF	713:728	37 °C. CL-CD-MOF	713:728	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	7	8	theme	G-GH/CL-CD-MOF	1177:1190	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	10	9	theme	G-GH/CL-CD-MOF	1514:1527	arg1	hydrogel					1543:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	1	10	theme	articular	214:222	arg1	degradation					234:244	articular cartilage degradation	214:244	articular cartilage degradation	214:244	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	12	11	theme	composite	1815:1823	arg1	hydrogel					1825:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	1	12	theme	degradation	234:244	arg1	Osteoarthritis					178:191	Osteoarthritis	178:191	Osteoarthritis (OA)	178:196	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	1	12	theme	degradation	234:244	arg1	disease					203:209	a disease	201:209	a disease of articular cartilage degradation and inflammation of the joint capsule	201:282	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	8	13	theme	composite	1297:1305	arg1	hydrogel					1307:1314	G-GH/CL-CD-MOF composite hydrogel	1282:1314	G-GH/CL-CD-MOF composite hydrogel	1282:1314	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	6	14	theme	high-concentration	1054:1071	arg1	IBU					1084:1086	IBU	1084:1086	IBU	1084:1086	CL-CD-MOF@IBU was prepared by immersing CL-CD-MOF in high-concentration ibuprofen (IBU) solution.					
35349993	6	14	theme	high-concentration	1054:1071	arg1	ibuprofen					1073:1081	high-concentration ibuprofen	1054:1081	high-concentration ibuprofen (IBU) solution	1054:1096	CL-CD-MOF@IBU was prepared by immersing CL-CD-MOF in high-concentration ibuprofen (IBU) solution.					
35349993	4	15	theme	water	693:697	arg1	solubility					699:708	water solubility	693:708	water solubility	693:708	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	7	16	theme	mixed	1151:1155	arg1	solution					1157:1164	Gel and GH mixed solution	1140:1164	solution	1157:1164	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	1	17	theme	inflammation	250:261	arg1	Osteoarthritis					178:191	Osteoarthritis	178:191	Osteoarthritis (OA)	178:196	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	1	17	theme	inflammation	250:261	arg1	disease					203:209	a disease	201:209	a disease of articular cartilage degradation and inflammation of the joint capsule	201:282	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	7	18	theme	@	1108:1108	arg1	IBU					1109:1111	CL-CD-MOF@IBU	1099:1111	CL-CD-MOF@IBU	1099:1111	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	8	19	theme	non-linear	1325:1334	arg1	behavior					1344:1351	a non-linear elastic behavior	1323:1351	a non-linear elastic behavior	1323:1351	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	4	20	theme	chemical	771:778	arg1	reaction					780:787	a simple one-step chemical reaction	753:787	a simple one-step chemical reaction	753:787	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	9	21	theme	cyclic	1358:1363	arg1	compression					1383:1393	The cyclic loading-unloading compression	1354:1393	The cyclic loading-unloading compression	1354:1393	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	12	22	theme	G-GH/CL-CD-MOF	1796:1809	arg1	hydrogel					1825:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	23	theme	IBU	1811:1813	arg1	hydrogel					1825:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	0	24	theme	long-term	107:115	arg1	frameworks					73:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks	0:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term	0:115	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	5	25	theme	diffraction	899:909	arg1	analysis					911:918	Electron microscopy and x-ray diffraction analysis	869:918	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF	869:931	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	5	26	theme	chaotic	973:979	arg1	structure					990:998	a chaotic internal structure	971:998	a chaotic internal structure	971:998	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	4	27	theme	Polyethylene	560:571	arg1	agent					618:622	the crosslinking agent	601:622	the crosslinking agent of GH	601:628	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	27	theme	Polyethylene	560:571	arg1	ether					591:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	28	theme	simple	755:760	arg1	reaction					780:787	a simple one-step chemical reaction	753:787	a simple one-step chemical reaction	753:787	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	0	29	theme	drug	127:130	arg1	system					141:146	drug delivery system	127:146	drug delivery system for osteoarthritis treatment	127:175	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	4	30	theme	diglycidyl	580:589	arg1	agent					618:622	the crosslinking agent	601:622	the crosslinking agent of GH	601:628	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	30	theme	diglycidyl	580:589	arg1	ether					591:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	10	31	theme	IBU	1529:1531	arg1	hydrogel					1543:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	4	32	dep	Gel	634:636	arg1	solve					641:645	solve	641:645	to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF	638:728	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	12	33	theme	drug	1744:1747	arg1	release					1749:1755	sustained drug release	1734:1755	sustained drug release behavior	1734:1764	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	0	34	theme	osteoarthritis	152:165	arg1	treatment					167:175	osteoarthritis treatment	152:175	osteoarthritis treatment	152:175	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	9	35	theme	composite	1439:1447	arg1	hydrogel					1449:1456	the G-GH/CL-CD-MOF composite hydrogel	1420:1456	the G-GH/CL-CD-MOF composite hydrogel	1420:1456	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	0	36	theme	Gelatin-glucosamine	0:18	arg1	frameworks					73:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks	0:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term	0:115	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	2	37	theme	anti-inflammatory	295:311	arg1	therapy					313:319	anti-inflammatory therapy	295:319	anti-inflammatory therapy	295:319	Combining anti-inflammatory therapy with nutritional supplement is an effective means for the treatment of OA.					
35349993	12	38	theme	mechanical	1711:1720	arg1	properties					1722:1731	the certain mechanical properties	1699:1731	the certain mechanical properties	1699:1731	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	39	theme	hydroxyl	818:825	arg1	groups					827:832	the hydrophilic hydroxyl groups	802:832	the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate	802:866	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	0	40	theme	metal-organic	59:71	arg1	frameworks					73:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks	0:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term	0:115	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	7	41	theme	delivery	1240:1247	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	12	42	theme	sustained	1904:1912	arg1	supplement					1926:1935	long-term sustained nutritional supplement	1894:1935	long-term sustained nutritional supplement	1894:1935	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	5	43	theme	Electron	869:876	arg1	microscopy					878:887	Electron microscopy	869:887	Electron microscopy	869:887	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	9	44	theme	%	1485:1485	arg1	strain					1487:1492	50% strain	1483:1492	50% strain	1483:1492	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	12	45	theme	supplement	1926:1935	arg1	treatment					1881:1889	OA treatment	1878:1889	OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously	1878:1971	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	46	theme	crosslinking	605:616	arg1	agent					618:622	the crosslinking agent	601:622	the crosslinking agent of GH	601:628	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	46	theme	crosslinking	605:616	arg1	ether					591:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	10	47	theme	IBU	1582:1584	arg1	IBU					1582:1584	IBU	1582:1584	IBU	1582:1584	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	10	47	theme	IBU	1582:1584	arg1	%					1577:1577	61%	1575:1577	61% of IBU	1575:1584	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	2	48	theme	OA	392:393	arg1	treatment					379:387	the treatment	375:387	the treatment of OA	375:393	Combining anti-inflammatory therapy with nutritional supplement is an effective means for the treatment of OA.					
35349993	1	49	theme	joint	270:274	arg1	capsule					276:282	the joint capsule	266:282	the joint capsule	266:282	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	12	50	theme	OA	1878:1879	arg1	treatment					1881:1889	OA treatment	1878:1889	OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously	1878:1971	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	5	51	theme	porous	948:953	arg1	morphology					955:964	perfect porous morphology	940:964	perfect porous morphology	940:964	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	4	52	theme	mechanical	667:676	arg1	properties					678:687	poor mechanical properties	662:687	poor mechanical properties	662:687	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	7	53	theme	composite	1196:1204	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	6	54	theme	CL-CD-MOF	1001:1009	arg1	IBU					1011:1013	CL-CD-MOF@IBU	1001:1013	CL-CD-MOF@IBU	1001:1013	CL-CD-MOF@IBU was prepared by immersing CL-CD-MOF in high-concentration ibuprofen (IBU) solution.					
35349993	7	55	theme	@	1191:1191	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	2	56	theme	effective	355:363	arg1	means					365:369	an effective means	352:369	an effective means for the treatment of OA	352:393	Combining anti-inflammatory therapy with nutritional supplement is an effective means for the treatment of OA.					
35349993	11	57	theme	G-GH/CL-CD-MOF	1600:1613	arg1	IBU					1615:1617	G-GH/CL-CD-MOF@IBU	1600:1617	G-GH/CL-CD-MOF@IBU	1600:1617	G-GH/CL-CD-MOF@IBU exhibited good biocompatibility during co-culture with MC3T3-E1 cells.					
35349993	5	58	theme	perfect	940:946	arg1	morphology					955:964	perfect porous morphology	940:964	perfect porous morphology	940:964	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	7	59	theme	sustained	1225:1233	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	12	60	theme	hydrogel	1825:1832	arg1	properties					1722:1731	the certain mechanical properties	1699:1731	the certain mechanical properties	1699:1731	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	60	theme	hydrogel	1825:1832	arg1	biocompatibility					1776:1791	good biocompatibility	1771:1791	good biocompatibility	1771:1791	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	60	theme	hydrogel	1825:1832	arg1	behavior					1757:1764	sustained drug release behavior	1734:1764	sustained drug release behavior	1734:1764	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	8	61	theme	elastic	1336:1342	arg1	behavior					1344:1351	a non-linear elastic behavior	1323:1351	a non-linear elastic behavior	1323:1351	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	1	62	theme	cartilage	224:232	arg1	degradation					234:244	articular cartilage degradation	214:244	articular cartilage degradation	214:244	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	6	63	theme	ibuprofen	1073:1081	arg1	solution					1089:1096	high-concentration ibuprofen (IBU) solution	1054:1096	high-concentration ibuprofen (IBU) solution	1054:1096	CL-CD-MOF@IBU was prepared by immersing CL-CD-MOF in high-concentration ibuprofen (IBU) solution.					
35349993	4	64	with	CD-MOF	837:842	arg1	carbonate					858:866	diphenyl carbonate	849:866	diphenyl carbonate	849:866	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	7	65	theme	GH	1148:1149	arg1	solution					1157:1164	Gel and GH mixed solution	1140:1164	solution	1157:1164	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	11	66	theme	good	1629:1632	arg1	biocompatibility					1634:1649	good biocompatibility	1629:1649	good biocompatibility	1629:1649	G-GH/CL-CD-MOF@IBU exhibited good biocompatibility during co-culture with MC3T3-E1 cells.					
35349993	8	67	theme	G-GH/CL-CD-MOF	1282:1295	arg1	hydrogel					1307:1314	G-GH/CL-CD-MOF composite hydrogel	1282:1314	G-GH/CL-CD-MOF composite hydrogel	1282:1314	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	7	68	theme	Gel	1140:1142	arg1	solution					1157:1164	Gel and GH mixed solution	1140:1164	solution	1157:1164	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	5	69	theme	CL-CD-MOF	923:931	arg1	analysis					911:918	Electron microscopy and x-ray diffraction analysis	869:918	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF	869:931	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	8	70	theme	hydrogel	1307:1314	arg1	curve					1273:1277	The compression curve	1257:1277	The compression curve of G-GH/CL-CD-MOF composite hydrogel	1257:1314	The compression curve of G-GH/CL-CD-MOF composite hydrogel showed a non-linear elastic behavior.					
35349993	4	71	theme	solubility	699:708	arg1	problem					651:657	the problem	647:657	the problem of poor mechanical properties and water solubility	647:708	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	72	theme	one-step	762:769	arg1	reaction					780:787	a simple one-step chemical reaction	753:787	a simple one-step chemical reaction	753:787	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	9	73	theme	loading-unloading	1365:1381	arg1	compression					1383:1393	The cyclic loading-unloading compression	1354:1393	The cyclic loading-unloading compression	1354:1393	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	2	74	theme	nutritional	326:336	arg1	supplement					338:347	nutritional supplement	326:347	nutritional supplement	326:347	Combining anti-inflammatory therapy with nutritional supplement is an effective means for the treatment of OA.					
35349993	7	75	theme	CL-CD-MOF	1099:1107	arg1	IBU					1109:1111	CL-CD-MOF@IBU	1099:1111	CL-CD-MOF@IBU	1099:1111	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	12	76	theme	@	1810:1810	arg1	hydrogel					1825:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	G-GH/CL-CD-MOF@IBU composite hydrogel	1796:1832	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	77	theme	glycol	573:578	arg1	agent					618:622	the crosslinking agent	601:622	the crosslinking agent of GH	601:628	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	77	theme	glycol	573:578	arg1	ether					591:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	0	78	theme	delivery	132:139	arg1	system					141:146	drug delivery system	127:146	drug delivery system for osteoarthritis treatment	127:175	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35349993	5	79	theme	internal	981:988	arg1	structure					990:998	a chaotic internal structure	971:998	a chaotic internal structure	971:998	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	10	80	theme	composite	1533:1541	arg1	hydrogel					1543:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	12	81	theme	good	1771:1774	arg1	biocompatibility					1776:1791	good biocompatibility	1771:1791	good biocompatibility	1771:1791	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	10	82	theme	@	1528:1528	arg1	hydrogel					1543:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	the G-GH/CL-CD-MOF@IBU composite hydrogel	1510:1550	On the day 14, the G-GH/CL-CD-MOF@IBU composite hydrogel was degraded by 87.1%, 61% of IBU was released.					
35349993	12	83	contain	has	1849:1851	arg2	application					1863:1873	potential application	1853:1873	potential application	1853:1873	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	83	contain	has	1849:1851	arg1	it					1846:1847	it	1846:1847	it	1846:1847	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	9	84	theme	G-GH/CL-CD-MOF	1424:1437	arg1	hydrogel					1449:1456	the G-GH/CL-CD-MOF composite hydrogel	1420:1456	the G-GH/CL-CD-MOF composite hydrogel	1420:1456	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	4	85	from	groups	827:832	arg1	CD-MOF					837:842	CD-MOF	837:842	CD-MOF with diphenyl carbonate	837:866	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	12	86	theme	sustained	1734:1742	arg1	release					1749:1755	sustained drug release	1734:1755	sustained drug release behavior	1734:1764	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	5	87	theme	microscopy	878:887	arg1	analysis					911:918	Electron microscopy and x-ray diffraction analysis	869:918	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF	869:931	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	9	88	theme	hydrogel	1449:1456	arg1	shape					1411:1415	the shape	1407:1415	the shape of the G-GH/CL-CD-MOF composite hydrogel	1407:1456	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	9	88	theme	hydrogel	1449:1456	arg1	intact					1470:1475	intact	1470:1475	intact	1470:1475	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	12	89	theme	release	1749:1755	arg1	behavior					1757:1764	sustained drug release behavior	1734:1764	sustained drug release behavior	1734:1764	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	90	theme	GH	627:628	arg1	agent					618:622	the crosslinking agent	601:622	the crosslinking agent of GH	601:628	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	90	theme	GH	627:628	arg1	ether					591:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether	560:595	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	5	91	theme	x-ray	893:897	arg1	diffraction					899:909	x-ray diffraction	893:909	x-ray diffraction	893:909	Electron microscopy and x-ray diffraction analysis of CL-CD-MOF showed perfect porous morphology with a chaotic internal structure.					
35349993	12	92	theme	certain	1703:1709	arg1	properties					1722:1731	the certain mechanical properties	1699:1731	the certain mechanical properties	1699:1731	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	93	theme	hydrophilic	806:816	arg1	groups					827:832	the hydrophilic hydroxyl groups	802:832	the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate	802:866	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	7	94	theme	drug	1235:1238	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	11	95	theme	MC3T3-E1	1674:1681	arg1	cells					1683:1687	MC3T3-E1 cells	1674:1687	MC3T3-E1 cells	1674:1687	G-GH/CL-CD-MOF@IBU exhibited good biocompatibility during co-culture with MC3T3-E1 cells.					
35349993	7	96	theme	long-term	1215:1223	arg1	system					1249:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system	1177:1254	CL-CD-MOF@IBU was uniformly dispersed in Gel and GH mixed solution to prepare G-GH/CL-CD-MOF@IBU composite hydrogel long-term sustained drug delivery system.					
35349993	9	97	theme	50	1483:1484	arg1	%					1485:1485	%	1485:1485	%	1485:1485	The cyclic loading-unloading compression showed that the shape of the G-GH/CL-CD-MOF composite hydrogel can be kept intact under 50% strain.					
35349993	12	98	theme	anti-inflammatory	1941:1957	arg1	treatment					1881:1889	OA treatment	1878:1889	OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously	1878:1971	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	99	theme	long-term	1894:1902	arg1	supplement					1926:1935	long-term sustained nutritional supplement	1894:1935	long-term sustained nutritional supplement	1894:1935	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	12	100	theme	nutritional	1914:1924	arg1	supplement					1926:1935	long-term sustained nutritional supplement	1894:1935	long-term sustained nutritional supplement	1894:1935	Briefly, the certain mechanical properties, sustained drug release behavior, and good biocompatibility of G-GH/CL-CD-MOF@IBU composite hydrogel showed that it has potential application in OA treatment of long-term sustained nutritional supplement and anti-inflammatory synchronously.					
35349993	4	101	theme	poor	662:665	arg1	properties					678:687	poor mechanical properties	662:687	poor mechanical properties	662:687	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	4	102	theme	diphenyl	849:856	arg1	carbonate					858:866	diphenyl carbonate	849:866	diphenyl carbonate	849:866	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	3	103	theme	composite	540:548	arg1	hydrogel					550:557	gelatin (Gel)-glucosamine hydrochloride (GH) mixed crosslinked-cyclodextrin metal-organic framework (G-GH/CL-CD-MOF) composite hydrogel	423:557	gelatin (Gel)-glucosamine hydrochloride (GH) mixed crosslinked-cyclodextrin metal-organic framework (G-GH/CL-CD-MOF) composite hydrogel	423:557	In this study, we prepared gelatin (Gel)-glucosamine hydrochloride (GH) mixed crosslinked-cyclodextrin metal-organic framework (G-GH/CL-CD-MOF) composite hydrogel.					
35349993	1	104	theme	capsule	276:282	arg1	inflammation					250:261	inflammation	250:261	inflammation	250:261	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	1	104	theme	capsule	276:282	arg1	degradation					234:244	articular cartilage degradation	214:244	articular cartilage degradation	214:244	Osteoarthritis (OA) is a disease of articular cartilage degradation and inflammation of the joint capsule.					
35349993	4	105	theme	properties	678:687	arg1	problem					651:657	the problem	647:657	the problem of poor mechanical properties and water solubility	647:708	Polyethylene glycol diglycidyl ether was the crosslinking agent of GH and Gel to solve the problem of poor mechanical properties and water solubility at 37 °C. CL-CD-MOF was fabricated through a simple one-step chemical reaction to crosslink the hydrophilic hydroxyl groups in CD-MOF with diphenyl carbonate.					
35349993	0	106	theme	hydrochloride/crosslinked-cyclodextrin	20:57	arg1	frameworks					73:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks	0:82	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term	0:115	Gelatin-glucosamine hydrochloride/crosslinked-cyclodextrin metal-organic frameworks@IBU composite hydrogel long-term sustained drug delivery system for osteoarthritis treatment.					
35569675	0	0	theme	selective	85:93	arg1	oxidation					105:113	selective periodate oxidation	85:113	selective periodate oxidation	85:113	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	3	1	theme	crystallinity	706:718	arg1	index					720:724	the crystallinity index	702:724	the crystallinity index of obtained di-aldehyde chitin	702:755	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	4	2	theme	maximum	886:892	arg1	value					894:898	a maximum value	884:898	a maximum value of around 0.42 mmol/g	884:920	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	5	3	theme	nanocrystals	1149:1160	arg1	morphology					1128:1137	morphology	1128:1137	morphology	1128:1137	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	5	3	theme	nanocrystals	1149:1160	arg1	efficiency					1113:1122	dispersion efficiency	1102:1122	dispersion efficiency	1102:1122	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	4	4	theme	addition	800:807	arg1	degree					762:767	The degree	758:767	The degree of deacetylation and periodate addition	758:807	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	4	5	theme	periodate	790:798	arg1	addition					800:807	periodate addition	790:807	periodate addition	790:807	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	5	6	dep	efficiency	1113:1122	arg1	the					1098:1100	the	1098:1100	the	1098:1100	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	2	7	from	oxidation	450:458	arg1	study					468:472	this study	463:472	this study	463:472	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	3	8	theme	crystalline	521:531	arg1	surface					505:511	the surface	501:511	the surface of both crystalline and amorphous regions	501:553	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	4	9	theme	deacetylation	772:784	arg1	degree					762:767	The degree	758:767	The degree of deacetylation and periodate addition	758:807	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	0	10	theme	periodate	95:103	arg1	oxidation					105:113	selective periodate oxidation	85:113	selective periodate oxidation	85:113	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	3	11	theme	obtained	729:736	arg1	chitin					750:755	obtained di-aldehyde chitin	729:755	obtained di-aldehyde chitin	729:755	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	5	12	theme	chitin	1030:1035	arg1	content					1006:1012	the carboxyl content	993:1012	the carboxyl content of tri-carboxyl chitin	993:1035	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	6	13	theme	97 nm	1263:1267	arg1	value					1224:1228	a ζ-potential value	1210:1228	a ζ-potential value of -42 mV	1210:1238	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	6	13	theme	97 nm	1263:1267	arg1	size					1255:1258	an average size	1244:1258	an average size of 97 nm	1244:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	2	14	theme	modification	286:297	arg1	difficulty					263:272	The difficulty	259:272	The difficulty	259:272	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	3	15	theme	di-aldehyde	738:748	arg1	chitin					750:755	obtained di-aldehyde chitin	729:755	obtained di-aldehyde chitin	729:755	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	4	16	theme	di-aldehyde	860:870	arg1	chitin					872:877	di-aldehyde chitin	860:877	di-aldehyde chitin	860:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	2	17	theme	aldehyde	277:284	arg1	modification					286:297	aldehyde modification	277:297	aldehyde modification	277:297	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	1	18	theme	food	170:173	arg1	waste					175:179	food waste	170:179	food waste	170:179	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	6	19	theme	-42 mV	1233:1238	arg1	value					1224:1228	a ζ-potential value	1210:1228	a ζ-potential value of -42 mV	1210:1238	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	6	19	theme	-42 mV	1233:1238	arg1	size					1255:1258	an average size	1244:1258	an average size of 97 nm	1244:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	2	20	theme	facile	390:395	arg1	route					397:401	a facile route	388:401	a facile route of partial deacetylation followed by periodate oxidation in this study	388:472	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	6	21	theme	emulsion	1318:1325	arg1	stabilizers					1327:1337	emulsion stabilizers	1318:1337	emulsion stabilizers	1318:1337	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	0	22	theme	Facile	0:5	arg1	route					7:11	Facile route	0:11	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin	0:71	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	4	23	theme	chitin	872:877	arg1	content					849:855	the aldehyde content	836:855	the aldehyde content of di-aldehyde chitin	836:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	5	24	theme	carboxyl	997:1004	arg1	content					1006:1012	the carboxyl content	993:1012	the carboxyl content of tri-carboxyl chitin	993:1035	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	0	25	theme	tri-carboxyl	16:27	arg1	nanocrystals					36:47	tri-carboxyl chitin nanocrystals	16:47	tri-carboxyl chitin nanocrystals	16:47	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	5	26	theme	chitin	1142:1147	arg1	nanocrystals					1149:1160	chitin nanocrystals	1142:1160	chitin nanocrystals	1142:1160	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	4	27	theme	aldehyde	840:847	arg1	content					849:855	the aldehyde content	836:855	the aldehyde content of di-aldehyde chitin	836:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	3	28	dep	crystalline	521:531	arg1	regions					547:553	regions	547:553	regions	547:553	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	5	29	theme	tri-carboxyl	1017:1028	arg1	chitin					1030:1035	tri-carboxyl chitin	1017:1035	tri-carboxyl chitin	1017:1035	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	3	30	theme	chitin	750:755	arg1	index					720:724	the crystallinity index	702:724	the crystallinity index of obtained di-aldehyde chitin	702:755	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	3	31	theme	amorphous	537:545	arg1	surface					505:511	the surface	501:511	the surface of both crystalline and amorphous regions	501:553	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	3	32	theme	chitin	661:666	arg1	chains					668:673	chitin chains	661:673	chitin chains	661:673	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	2	33	theme	deacetylation	414:426	arg1	route					397:401	a facile route	388:401	a facile route of partial deacetylation followed by periodate oxidation in this study	388:472	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	3	34	from	increase	690:697	arg1	index					720:724	the crystallinity index	702:724	the crystallinity index of obtained di-aldehyde chitin	702:755	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	5	35	theme	2,2,6,6-tetramethylpiperidine-1-oxyl-mediated	936:980	arg1	oxidation					982:990	further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation	928:990	further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation	928:990	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	3	36	theme	chains	668:673	arg1	cleavage					649:656	the inevitable cleavage	634:656	the inevitable cleavage of chitin chains	634:673	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	3	37	theme	periodate	607:615	arg1	oxidation					617:625	the following periodate oxidation	593:625	the following periodate oxidation	593:625	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	2	38	theme	partial	406:412	arg1	deacetylation					414:426	partial deacetylation	406:426	partial deacetylation followed by periodate oxidation in this study	406:472	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	0	39	theme	chitin	29:34	arg1	nanocrystals					36:47	tri-carboxyl chitin nanocrystals	16:47	tri-carboxyl chitin nanocrystals	16:47	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	2	40	theme	periodate	440:448	arg1	oxidation					450:458	periodate oxidation	440:458	periodate oxidation in this study	440:472	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	1	41	theme	important	200:208	arg1	biopolymer					224:233	an important biodegradable biopolymer	197:233	an important biodegradable biopolymer in composite materials	197:256	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	0	42	theme	di-aldehyde	54:64	arg1	chitin					66:71	di-aldehyde chitin	54:71	di-aldehyde chitin	54:71	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	6	43	contain	have	1269:1272	arg2	application					1284:1294	potential application	1274:1294	potential application	1274:1294	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	6	43	contain	have	1269:1272	arg1	nanocrystals					1192:1203	The obtained rod-like chitin nanocrystals	1163:1203	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm	1163:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	0	44	from	chitin	66:71	arg1	route					7:11	Facile route	0:11	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin	0:71	Facile route to tri-carboxyl chitin nanocrystals from di-aldehyde chitin modified by selective periodate oxidation.					
35569675	5	45	theme	critical	1081:1088	arg1	role					1090:1093	a critical role	1079:1093	a critical role	1079:1093	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	6	46	theme	obtained	1167:1174	arg1	nanocrystals					1192:1203	The obtained rod-like chitin nanocrystals	1163:1203	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm	1163:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	2	47	theme	nanocrystals	348:359	arg1	application					326:336	the application	322:336	the application of chitin nanocrystals	322:359	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	6	48	with	nanocrystals	1192:1203	arg1	value					1224:1228	a ζ-potential value	1210:1228	a ζ-potential value of -42 mV	1210:1238	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	6	48	with	nanocrystals	1192:1203	arg1	size					1255:1258	an average size	1244:1258	an average size of 97 nm	1244:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	3	49	theme	following	597:605	arg1	oxidation					617:625	the following periodate oxidation	593:625	the following periodate oxidation	593:625	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	2	50	theme	chitin	341:346	arg1	nanocrystals					348:359	chitin nanocrystals	341:359	chitin nanocrystals	341:359	The difficulty of aldehyde modification, which greatly limited the application of chitin nanocrystals, was addressed by applying a facile route of partial deacetylation followed by periodate oxidation in this study.					
35569675	6	51	theme	potential	1274:1282	arg1	application					1284:1294	potential application	1274:1294	potential application	1274:1294	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	4	52	theme	limited	813:819	arg1	improvement					821:831	limited improvement	813:831	limited improvement in the aldehyde content of di-aldehyde chitin	813:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	6	53	theme	chitin	1185:1190	arg1	nanocrystals					1192:1203	The obtained rod-like chitin nanocrystals	1163:1203	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm	1163:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	6	54	theme	ζ-potential	1212:1222	arg1	value					1224:1228	a ζ-potential value	1210:1228	a ζ-potential value of -42 mV	1210:1238	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	1	55	theme	biodegradable	210:222	arg1	biopolymer					224:233	an important biodegradable biopolymer	197:233	an important biodegradable biopolymer in composite materials	197:256	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	1	56	from	biopolymer	224:233	arg1	materials					248:256	composite materials	238:256	composite materials	238:256	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	5	57	theme	dispersion	1102:1111	arg1	efficiency					1113:1122	dispersion efficiency	1102:1122	dispersion efficiency	1102:1122	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	3	58	theme	inevitable	638:647	arg1	cleavage					649:656	the inevitable cleavage	634:656	the inevitable cleavage of chitin chains	634:673	Deacetylation occurred on the surface of both crystalline and amorphous regions, which were significantly degraded in the following periodate oxidation due to the inevitable cleavage of chitin chains, leading to an increase in the crystallinity index of obtained di-aldehyde chitin.					
35569675	4	59	from	improvement	821:831	arg1	content					849:855	the aldehyde content	836:855	the aldehyde content of di-aldehyde chitin	836:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	6	60	theme	rod-like	1176:1183	arg1	nanocrystals					1192:1203	The obtained rod-like chitin nanocrystals	1163:1203	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm	1163:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	5	61	theme	further	928:934	arg1	oxidation					982:990	further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation	928:990	further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation	928:990	With further 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation, the carboxyl content of tri-carboxyl chitin was improved to 1.58 mmol/g, which played a critical role in the dispersion efficiency and morphology of chitin nanocrystals.					
35569675	1	62	theme	polysaccharide	134:147	arg1	kind					126:129	a kind	124:129	a kind of polysaccharide mainly obtained from food waste	124:179	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	1	62	theme	polysaccharide	134:147	arg1	Chitin					116:121	Chitin	116:121	Chitin	116:121	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35569675	4	63	contain	had	809:811	arg1	degree					762:767	The degree	758:767	The degree of deacetylation and periodate addition	758:807	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	4	63	contain	had	809:811	arg2	improvement					821:831	limited improvement	813:831	limited improvement in the aldehyde content of di-aldehyde chitin	813:877	The degree of deacetylation and periodate addition had limited improvement in the aldehyde content of di-aldehyde chitin with a maximum value of around 0.42 mmol/g.					
35569675	6	64	theme	average	1247:1253	arg1	size					1255:1258	an average size	1244:1258	an average size of 97 nm	1244:1267	The obtained rod-like chitin nanocrystals with a ζ-potential value of -42 mV and an average size of 97 nm have potential application in dye-adsorption and emulsion stabilizers.					
35569675	1	65	theme	composite	238:246	arg1	materials					248:256	composite materials	238:256	composite materials	238:256	Chitin, a kind of polysaccharide mainly obtained from food waste, has emerged as an important biodegradable biopolymer in composite materials.					
35324155	4	0	theme	crystallization	499:513	arg1	behavior					515:522	stretch-induced crystallization behavior	483:522	stretch-induced crystallization behavior	483:522	In this study, we found stretch-induced crystallization behavior during the transition from solution to gel via coagulation.					
35324155	8	1	theme	liquid	963:968	arg1	concentration					911:923	the concentration	907:923	the concentration of the solution	907:939	This crystallization behavior depends on the concentration of the solution and the type of ionic liquid.					
35324155	8	1	theme	liquid	963:968	arg1	type					949:952	the type	945:952	the type of ionic liquid	945:968	This crystallization behavior depends on the concentration of the solution and the type of ionic liquid.					
35324155	1	2	theme	cellulose	163:171	arg1	regulation					137:146	structural regulation	126:146	structural regulation of regenerated cellulose	126:171	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	5	3	theme	hydrogel	615:622	arg1	fiber					624:628	the hydrogel fiber	611:628	the hydrogel fiber	611:628	The crystallinity index of the hydrogel fiber increases with the stretch ratio (SR).					
35324155	2	4	theme	composite	290:298	arg1	"					299:299	a "composite"	287:299	a "composite" comprising amorphous and crystalline fractions	287:346	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	2	4	theme	composite	290:298	arg1	Cellulose					247:255	Cellulose fiber and films	247:271	Cellulose fiber and films	247:271	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	5	5	theme	fiber	624:628	arg1	index					602:606	The crystallinity index	584:606	The crystallinity index of the hydrogel fiber	584:628	The crystallinity index of the hydrogel fiber increases with the stretch ratio (SR).					
35324155	8	6	theme	crystallization	871:885	arg1	behavior					887:894	This crystallization behavior	866:894	This crystallization behavior	866:894	This crystallization behavior depends on the concentration of the solution and the type of ionic liquid.					
35324155	3	7	theme	cellulose	438:446	arg1	materials					448:456	cellulose materials	438:456	cellulose materials	438:456	The regulation of the crystalline structure is of great importance for the properties of cellulose materials.					
35324155	4	8	theme	stretch-induced	483:497	arg1	behavior					515:522	stretch-induced crystallization behavior	483:522	stretch-induced crystallization behavior	483:522	In this study, we found stretch-induced crystallization behavior during the transition from solution to gel via coagulation.					
35324155	9	9	theme	stretch-induced	976:990	arg1	crystallization					992:1006	This stretch-induced crystallization	971:1006	This stretch-induced crystallization	971:1006	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
35324155	6	10	theme	cellulose	705:713	arg1	hydrate					718:724	the cellulose II hydrate	701:724	the cellulose II hydrate	701:724	X-ray diffraction revealed that the cellulose II hydrate formed in the stretched hydrogel fibers.					
35324155	3	11	theme	materials	448:456	arg1	properties					424:433	the properties	420:433	the properties of cellulose materials	420:456	The regulation of the crystalline structure is of great importance for the properties of cellulose materials.					
35324155	5	12	theme	stretch	649:655	arg1	SR					664:665	SR	664:665	SR	664:665	The crystallinity index of the hydrogel fiber increases with the stretch ratio (SR).					
35324155	5	12	theme	stretch	649:655	arg1	ratio					657:661	the stretch ratio	645:661	the stretch ratio (SR)	645:666	The crystallinity index of the hydrogel fiber increases with the stretch ratio (SR).					
35324155	5	13	theme	crystallinity	588:600	arg1	index					602:606	The crystallinity index	584:606	The crystallinity index of the hydrogel fiber	584:628	The crystallinity index of the hydrogel fiber increases with the stretch ratio (SR).					
35324155	2	14	theme	amorphous	312:320	arg1	fractions					338:346	amorphous and crystalline fractions	312:346	amorphous and crystalline fractions	312:346	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	0	15	theme	Stretch-Induced	0:14	arg1	Crystallization					16:30	Stretch-Induced Crystallization	0:30	Stretch-Induced Crystallization of Cellulose	0:43	Stretch-Induced Crystallization of Cellulose Spun from Ionic Liquid Solution.					
35324155	3	16	theme	crystalline	371:381	arg1	structure					383:391	the crystalline structure	367:391	the crystalline structure	367:391	The regulation of the crystalline structure is of great importance for the properties of cellulose materials.					
35324155	7	17	theme	dry	822:824	arg1	fibers					826:831	the dry fibers	818:831	the dry fibers	818:831	The mechanical properties and thermal stability of the dry fibers greatly improved against the SR.					
35324155	1	18	theme	efficient	100:108	arg1	solvents					116:123	efficient green solvents	100:123	efficient green solvents	100:123	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	1	19	theme	solution	198:205	arg1	process					207:213	the solution process	194:213	the solution process from an industrial perspective	194:244	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	3	20	theme	structure	383:391	arg1	regulation					353:362	The regulation	349:362	The regulation of the crystalline structure	349:391	The regulation of the crystalline structure is of great importance for the properties of cellulose materials.					
35324155	1	21	theme	green	110:114	arg1	solvents					116:123	efficient green solvents	100:123	efficient green solvents	100:123	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	7	22	theme	fibers	826:831	arg1	properties					782:791	The mechanical properties	767:791	The mechanical properties	767:791	The mechanical properties and thermal stability of the dry fibers greatly improved against the SR.					
35324155	7	22	theme	fibers	826:831	arg1	stability					805:813	thermal stability	797:813	thermal stability	797:813	The mechanical properties and thermal stability of the dry fibers greatly improved against the SR.					
35324155	6	23	theme	X-ray	669:673	arg1	diffraction					675:685	X-ray diffraction	669:685	X-ray diffraction	669:685	X-ray diffraction revealed that the cellulose II hydrate formed in the stretched hydrogel fibers.					
35324155	2	24	dep	Cellulose	247:255	arg1	films					267:271	films	267:271	films	267:271	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	2	24	dep	Cellulose	247:255	arg1	fiber					257:261	fiber	257:261	fiber	257:261	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	4	25	from	solution	551:558	arg1	transition					535:544	the transition	531:544	the transition from solution to gel	531:565	In this study, we found stretch-induced crystallization behavior during the transition from solution to gel via coagulation.					
35324155	9	26	theme	efficient	1020:1028	arg1	method					1030:1035	an efficient method	1017:1035	an efficient method for structural regulation in cellulose solution processing	1017:1094	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
35324155	0	27	theme	Cellulose	35:43	arg1	Crystallization					16:30	Stretch-Induced Crystallization	0:30	Stretch-Induced Crystallization of Cellulose	0:43	Stretch-Induced Crystallization of Cellulose Spun from Ionic Liquid Solution.					
35324155	0	28	theme	Liquid	61:66	arg1	Solution					68:75	Ionic Liquid Solution	55:75	Ionic Liquid Solution	55:75	Stretch-Induced Crystallization of Cellulose Spun from Ionic Liquid Solution.					
35324155	7	29	theme	thermal	797:803	arg1	stability					805:813	thermal stability	797:813	thermal stability	797:813	The mechanical properties and thermal stability of the dry fibers greatly improved against the SR.					
35324155	8	30	theme	solution	932:939	arg1	concentration					911:923	the concentration	907:923	the concentration of the solution	907:939	This crystallization behavior depends on the concentration of the solution and the type of ionic liquid.					
35324155	8	30	theme	solution	932:939	arg1	type					949:952	the type	945:952	the type of ionic liquid	945:968	This crystallization behavior depends on the concentration of the solution and the type of ionic liquid.					
35324155	1	31	theme	solvents	116:123	arg1	emergence					87:95	the emergence	83:95	the emergence of efficient green solvents	83:123	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	0	32	theme	Ionic	55:59	arg1	Solution					68:75	Ionic Liquid Solution	55:75	Ionic Liquid Solution	55:75	Stretch-Induced Crystallization of Cellulose Spun from Ionic Liquid Solution.					
35324155	7	33	theme	mechanical	771:780	arg1	properties					782:791	The mechanical properties	767:791	The mechanical properties	767:791	The mechanical properties and thermal stability of the dry fibers greatly improved against the SR.					
35324155	9	34	theme	structural	1041:1050	arg1	regulation					1052:1061	structural regulation	1041:1061	structural regulation in cellulose solution processing	1041:1094	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
35324155	6	35	theme	hydrogel	750:757	arg1	fibers					759:764	the stretched hydrogel fibers	736:764	the stretched hydrogel fibers	736:764	X-ray diffraction revealed that the cellulose II hydrate formed in the stretched hydrogel fibers.					
35324155	1	36	theme	structural	126:135	arg1	regulation					137:146	structural regulation	126:146	structural regulation of regenerated cellulose	126:171	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	1	37	theme	industrial	223:232	arg1	perspective					234:244	an industrial perspective	220:244	an industrial perspective	220:244	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	1	38	from	perspective	234:244	arg1	process					207:213	the solution process	194:213	the solution process from an industrial perspective	194:244	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	6	39	theme	stretched	740:748	arg1	fibers					759:764	the stretched hydrogel fibers	736:764	the stretched hydrogel fibers	736:764	X-ray diffraction revealed that the cellulose II hydrate formed in the stretched hydrogel fibers.					
35324155	9	40	from	regulation	1052:1061	arg1	processing					1085:1094	cellulose solution processing	1066:1094	cellulose solution processing	1066:1094	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
35324155	2	41	theme	crystalline	326:336	arg1	fractions					338:346	amorphous and crystalline fractions	312:346	amorphous and crystalline fractions	312:346	Cellulose fiber and films are viewed as a "composite" comprising amorphous and crystalline fractions.					
35324155	9	42	theme	cellulose	1066:1074	arg1	processing					1085:1094	cellulose solution processing	1066:1094	cellulose solution processing	1066:1094	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
35324155	3	43	theme	great	399:403	arg1	importance					405:414	great importance	399:414	great importance	399:414	The regulation of the crystalline structure is of great importance for the properties of cellulose materials.					
35324155	1	44	theme	regenerated	151:161	arg1	cellulose					163:171	regenerated cellulose	151:171	regenerated cellulose	151:171	With the emergence of efficient green solvents, structural regulation of regenerated cellulose is highly desired in the solution process from an industrial perspective.					
35324155	9	45	theme	solution	1076:1083	arg1	processing					1085:1094	cellulose solution processing	1066:1094	cellulose solution processing	1066:1094	This stretch-induced crystallization provides an efficient method for structural regulation in cellulose solution processing.					
37080023	6	0	theme	excellent	1174:1182	arg1	anti-fouling					1184:1195	excellent anti-fouling	1174:1195	excellent anti-fouling	1174:1195	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	3	1	with	cryogel	493:499	arg1	durability					570:579	durability	570:579	durability	570:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	1	with	cryogel	493:499	arg1	size					539:542	regulable pore size	524:542	regulable pore size	524:542	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	1	with	cryogel	493:499	arg1	elasticity					555:564	excellent elasticity	545:564	excellent elasticity	545:564	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	6	2	theme	solution	1317:1324	arg1	purification					1258:1269	the purification	1254:1269	the purification of both oil/water emulsion and methylene blue solution	1254:1324	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	5	3	theme	cryogel	1019:1025	arg1	incompressibility					986:1002	incompressibility	986:1002	incompressibility of traditional cryogel	986:1025	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	5	3	theme	cryogel	1019:1025	arg1	size					977:980	unregulatable pore size	958:980	unregulatable pore size	958:980	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	7	4	theme	SF-based	1366:1373	arg1	cryogel					1375:1381	SF-based cryogel	1366:1381	SF-based cryogel	1366:1381	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	5	5	theme	incompressibility	986:1002	arg1	shortcoming					943:953	the shortcoming	939:953	the shortcoming of unregulatable pore size and incompressibility of traditional cryogel	939:1025	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	1	6	theme	medicine	255:262	arg1	field					246:250	the field	242:250	the field of medicine	242:262	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	6	7	theme	blue	1312:1315	arg1	solution					1317:1324	methylene blue solution	1302:1324	methylene blue solution	1302:1324	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	7	8	theme	new-type	1424:1431	arg1	cryogel					1443:1449	new-type composite cryogel	1424:1449	new-type composite cryogel	1424:1449	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	3	9	theme	named	502:506	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	9	theme	named	502:506	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	5	10	theme	three-dimensional	878:894	arg1	structure					909:917	three-dimensional dual network structure	878:917	three-dimensional dual network structure	878:917	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	7	11	theme	dual-directional	1483:1498	arg1	strategy					1510:1517	dual-directional crosslink strategy	1483:1517	dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater	1483:1589	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	6	12	theme	self-cleaning	1211:1223	arg1	property					1225:1232	brilliant self-cleaning property	1201:1232	brilliant self-cleaning property	1201:1232	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	5	13	theme	dual	896:899	arg1	structure					909:917	three-dimensional dual network structure	878:917	three-dimensional dual network structure	878:917	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	3	14	theme	novel	468:472	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	14	theme	novel	468:472	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	4	15	theme	silk	684:687	arg1	SF					698:699	SF	698:699	SF	698:699	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	4	15	theme	silk	684:687	arg1	fibroin					689:695	silk fibroin	684:695	silk fibroin (SF)	684:700	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	6	16	theme	brilliant	1201:1209	arg1	property					1225:1232	brilliant self-cleaning property	1201:1232	brilliant self-cleaning property	1201:1232	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	3	17	theme	@	510:510	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	17	theme	@	510:510	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	4	18	theme	@	654:654	arg1	PVA/CS					655:660	The SF@PVA/CS	648:660	The SF@PVA/CS	648:660	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	6	19	theme	PVA/CS	1059:1064	arg1	membrane					1066:1073	the developed SF@PVA/CS membrane	1042:1073	the developed SF@PVA/CS membrane	1042:1073	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	6	20	theme	emulsion	1289:1296	arg1	purification					1258:1269	the purification	1254:1269	the purification of both oil/water emulsion and methylene blue solution	1254:1324	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	7	21	theme	crosslink	1500:1508	arg1	strategy					1510:1517	dual-directional crosslink strategy	1483:1517	dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater	1483:1589	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	7	22	theme	cryogel	1375:1381	arg1	application					1351:1361	the application	1347:1361	the application of SF-based cryogel	1347:1381	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	2	23	theme	incompressible	384:397	arg1	property					399:406	incompressible property	384:406	incompressible property	384:406	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	7	24	theme	novel	1396:1400	arg1	routine					1402:1408	a novel routine	1394:1408	a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater	1394:1589	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	6	25	theme	water	1088:1092	arg1	purification					1094:1105	water purification	1088:1105	water purification	1088:1105	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	1	26	theme	special	198:204	arg1	type					206:209	a special type	196:209	a special type of hydrogel	196:221	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	0	27	theme	Regulable	0:8	arg1	preparation					10:20	Regulable preparation	0:20	Regulable preparation of silk	0:28	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	6	28	theme	oil/water	1279:1287	arg1	emulsion					1289:1296	oil/water emulsion	1279:1296	oil/water emulsion	1279:1296	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	4	29	theme	polymer	769:775	arg1	hydrogel					777:784	polymer hydrogel	769:784	polymer hydrogel which was introduced into the inner bone scaffold of SF	769:840	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	5	30	theme	brand-new	850:858	arg1	cryogel					860:866	Such a brand-new cryogel	843:866	Such a brand-new cryogel	843:866	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	5	31	contain	possessed	868:876	arg1	cryogel					860:866	Such a brand-new cryogel	843:866	Such a brand-new cryogel	843:866	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	5	31	contain	possessed	868:876	arg2	structure					909:917	three-dimensional dual network structure	878:917	three-dimensional dual network structure	878:917	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	4	32	theme	SF	652:653	arg1	PVA/CS					655:660	The SF@PVA/CS	648:660	The SF@PVA/CS	648:660	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	0	33	theme	silk	25:28	arg1	preparation					10:20	Regulable preparation	0:20	Regulable preparation of silk	0:28	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	1	34	theme	porous	275:280	arg1	structure					282:290	porous structure	275:290	porous structure	275:290	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	0	35	theme	water	151:155	arg1	purification					157:168	multifunctional water purification	135:168	multifunctional water purification	135:168	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	6	36	theme	superior	1143:1150	arg1	permeation					1162:1171	superior selective permeation	1143:1171	superior selective permeation	1143:1171	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	3	37	theme	regulable	524:532	arg1	size					539:542	regulable pore size	524:542	regulable pore size	524:542	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	6	38	theme	SF	1056:1057	arg1	membrane					1066:1073	the developed SF@PVA/CS membrane	1042:1073	the developed SF@PVA/CS membrane	1042:1073	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	6	39	theme	first	1115:1119	arg1	time					1121:1124	the first time	1111:1124	the first time	1111:1124	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	0	40	theme	multifunctional	135:149	arg1	purification					157:168	multifunctional water purification	135:168	multifunctional water purification	135:168	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	3	41	theme	crosslink	628:636	arg1	strategy					638:645	a green dual-directional crosslink strategy	603:645	a green dual-directional crosslink strategy	603:645	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	42	theme	pore	534:537	arg1	size					539:542	regulable pore size	524:542	regulable pore size	524:542	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	1	43	theme	hydrogel	214:221	arg1	type					206:209	a special type	196:209	a special type of hydrogel	196:221	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	0	44	theme	composite	38:46	arg1	cryogel					48:54	composite cryogel	38:54	composite cryogel	38:54	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	6	45	used	used	1079:1082	arg2	membrane					1066:1073	the developed SF@PVA/CS membrane	1042:1073	the developed SF@PVA/CS membrane	1042:1073	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	6	46	theme	selective	1152:1160	arg1	permeation					1162:1171	superior selective permeation	1143:1171	superior selective permeation	1143:1171	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	5	47	theme	traditional	1007:1017	arg1	cryogel					1019:1025	traditional cryogel	1007:1025	traditional cryogel	1007:1025	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	1	48	theme	good	296:299	arg1	biocompatibilit					301:315	good biocompatibilit	296:315	good biocompatibilit	296:315	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	3	49	theme	green	605:609	arg1	strategy					638:645	a green dual-directional crosslink strategy	603:645	a green dual-directional crosslink strategy	603:645	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	2	50	theme	other	437:441	arg1	fields					443:448	other fields	437:448	other fields	437:448	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	4	51	theme	inner	816:820	arg1	scaffold					827:834	the inner bone scaffold	812:834	the inner bone scaffold of SF	812:840	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	3	52	theme	dual-directional	611:626	arg1	strategy					638:645	a green dual-directional crosslink strategy	603:645	a green dual-directional crosslink strategy	603:645	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	53	theme	excellent	545:553	arg1	elasticity					555:564	excellent elasticity	545:564	excellent elasticity	545:564	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	6	54	theme	developed	1046:1054	arg1	membrane					1066:1073	the developed SF@PVA/CS membrane	1042:1073	the developed SF@PVA/CS membrane	1042:1073	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	3	55	theme	silk	474:477	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	55	theme	silk	474:477	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	4	56	theme	SF	839:840	arg1	scaffold					827:834	the inner bone scaffold	812:834	the inner bone scaffold of SF	812:840	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	5	57	theme	pore	972:975	arg1	size					977:980	unregulatable pore size	958:980	unregulatable pore size	958:980	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	5	58	theme	unregulatable	958:970	arg1	size					977:980	unregulatable pore size	958:980	unregulatable pore size	958:980	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	3	59	theme	fibroin-based	479:491	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	59	theme	fibroin-based	479:491	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	7	60	theme	strategy	1510:1517	arg1	application					1468:1478	the application	1464:1478	the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater	1464:1589	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	7	61	theme	wastewater	1580:1589	arg1	purification					1564:1575	the purification	1560:1575	the purification of wastewater	1560:1589	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	5	62	theme	size	977:980	arg1	shortcoming					943:953	the shortcoming	939:953	the shortcoming of unregulatable pore size and incompressibility of traditional cryogel	939:1025	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	4	63	theme	polyvinyl	742:750	arg1	alcohol					752:758	polyvinyl alcohol	742:758	polyvinyl alcohol (PVA)	742:764	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	4	63	theme	polyvinyl	742:750	arg1	PVA					761:763	PVA	761:763	PVA	761:763	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	2	64	theme	great	327:331	arg1	challenges					333:342	great challenges	327:342	great challenges	327:342	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	4	65	theme	bone	705:708	arg1	scaffold					710:717	bone scaffold	705:717	bone scaffold	705:717	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	4	66	theme	bone	822:825	arg1	scaffold					827:834	the inner bone scaffold	812:834	the inner bone scaffold of SF	812:840	The SF@PVA/CS was prepared by using silk fibroin (SF) as bone scaffold, and chitosan (CS) and polyvinyl alcohol (PVA) as polymer hydrogel which was introduced into the inner bone scaffold of SF.					
37080023	5	67	theme	network	901:907	arg1	structure					909:917	three-dimensional dual network structure	878:917	three-dimensional dual network structure	878:917	Such a brand-new cryogel possessed three-dimensional dual network structure, which can overcome the shortcoming of unregulatable pore size and incompressibility of traditional cryogel.					
37080023	2	68	theme	irregular	360:368	arg1	size					375:378	its irregular pore size	356:378	its irregular pore size	356:378	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	6	69	theme	@	1058:1058	arg1	membrane					1066:1073	the developed SF@PVA/CS membrane	1042:1073	the developed SF@PVA/CS membrane	1042:1073	Additionally, the developed SF@PVA/CS membrane was used for water purification for the first time, which exhibited superior selective permeation, excellent anti-fouling and brilliant self-cleaning property, and it can achieve the purification of both oil/water emulsion and methylene blue solution.					
37080023	1	70	used	used	234:237	arg2	cryogel					185:191	the cryogel	181:191	the cryogel as a special type of hydrogel	181:221	Recently, the cryogel as a special type of hydrogel was widely used in the field of medicine due to its porous structure and good biocompatibilit.					
37080023	2	71	theme	pore	370:373	arg1	size					375:378	its irregular pore size	356:378	its irregular pore size	356:378	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	0	72	theme	dual-directional	59:74	arg1	crosslink					76:84	dual-directional crosslink	59:84	dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification	59:168	Regulable preparation of silk fibroin composite cryogel by dual-directional crosslink for achieving self-cleaning, superelasticity and multifunctional water purification.					
37080023	7	73	theme	composite	1433:1441	arg1	cryogel					1443:1449	new-type composite cryogel	1424:1449	new-type composite cryogel	1424:1449	This study expanded the application of SF-based cryogel, providing a novel routine for designing new-type composite cryogel and widening the application of dual-directional crosslink strategy developed in this study for facilitating the purification of wastewater.					
37080023	2	74	from	application	422:432	arg1	fields					443:448	other fields	437:448	other fields	437:448	However, great challenges existed for its irregular pore size and incompressible property, limiting its application in other fields.					
37080023	3	75	theme	SF	508:509	arg1	PVA/CS					511:516	named SF@PVA/CS	502:516	named SF@PVA/CS	502:516	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
37080023	3	75	theme	SF	508:509	arg1	cryogel					493:499	a novel silk fibroin-based cryogel	466:499	a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability	466:579	In this study, a novel silk fibroin-based cryogel (named SF@PVA/CS) with regulable pore size, excellent elasticity and durability was constructed using a green dual-directional crosslink strategy.					
36446493	4	0	theme	damaged	943:949	arg1	model					974:978	a damaged 10-mm peripheral nerve model	941:978	a damaged 10-mm peripheral nerve model	941:978	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	1	1	theme	composite	148:156	arg1	conduit					177:183	a chitosan-based composite multichannel nerve conduit	131:183	a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers	131:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	2	2	theme	appropriate	401:411	arg1	support					424:430	appropriate mechanical support	401:430	appropriate mechanical support	401:430	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	1	3	from	defect	333:338	arg1	rats					343:346	rats	343:346	rats	343:346	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	1	4	theme	multichannel	158:169	arg1	conduit					177:183	a chitosan-based composite multichannel nerve conduit	131:183	a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers	131:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	1	5	theme	NS-chitosan	277:287	arg1	fibers					290:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	0	6	theme	cell	101:104	arg1	survival					106:113	Schwann cell survival	93:113	Schwann cell survival	93:113	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	5	7	theme	nerve	1213:1217	arg1	repair					1219:1224	nerve repair	1213:1224	nerve repair	1213:1224	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	4	8	theme	peripheral	957:966	arg1	model					974:978	a damaged 10-mm peripheral nerve model	941:978	a damaged 10-mm peripheral nerve model	941:978	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	2	9	theme	PC-12	529:533	arg1	cells					535:539	PC-12 cells	529:539	PC-12 cells	529:539	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	3	10	from	effects	626:632	arg1	nerves					648:653	peripheral nerves	637:653	peripheral nerves	637:653	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	3	11	theme	damaged	747:753	arg1	cells					763:767	damaged Schwann cells	747:767	damaged Schwann cells	747:767	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	4	12	theme	nerve	913:917	arg1	reconstruction					919:932	a histologically and functionally successful nerve reconstruction	868:932	a histologically and functionally successful nerve reconstruction	868:932	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	1	13	theme	nerve	171:175	arg1	conduit					177:183	a chitosan-based composite multichannel nerve conduit	131:183	a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers	131:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	4	14	theme	successful	902:911	arg1	reconstruction					919:932	a histologically and functionally successful nerve reconstruction	868:932	a histologically and functionally successful nerve reconstruction	868:932	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	0	15	theme	Multichannel	0:11	arg1	conduit					19:25	Multichannel nerve conduit	0:25	Multichannel nerve conduit	0:25	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	3	16	theme	Bcl-2/Bax/caspase-3	781:799	arg1	pathway					801:807	the Bcl-2/Bax/caspase-3 pathway	777:807	the Bcl-2/Bax/caspase-3 pathway	777:807	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	0	17	theme	nerve	13:17	arg1	conduit					19:25	Multichannel nerve conduit	0:25	Multichannel nerve conduit	0:25	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	5	18	theme	bioactive	1188:1196	arg1	properties					1198:1207	good mechanical and bioactive properties	1168:1207	good mechanical and bioactive properties	1168:1207	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	2	19	theme	knitting	453:460	arg1	techniques					462:471	warp knitting techniques	448:471	warp knitting techniques	448:471	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	5	20	theme	inner	1152:1156	arg1	fiber					1158:1162	aligned inner fiber	1144:1162	aligned inner fiber	1144:1162	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	2	21	theme	external	378:385	arg1	pipeline					387:394	an external pipeline	375:394	an external pipeline with appropriate mechanical support	375:430	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	2	22	theme	warp	448:451	arg1	techniques					462:471	warp knitting techniques	448:471	warp knitting techniques	448:471	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	3	23	theme	Schwann	755:761	arg1	cells					763:767	damaged Schwann cells	747:767	damaged Schwann cells	747:767	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	4	24	theme	regenerative	989:1000	arg1	efficacy					1002:1009	regenerative efficacy	989:1009	regenerative efficacy equal to that of an autograft	989:1039	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	1	25	theme	warp-knitted	201:212	arg1	scaffold					223:230	a warp-knitted chitosan scaffold	199:230	a warp-knitted chitosan scaffold	199:230	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	0	26	theme	chitosan	36:43	arg1	derivates					45:53	chitosan derivates	36:53	chitosan derivates for peripheral nerve regeneration and Schwann cell survival	36:113	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	3	27	theme	cells	763:767	arg1	apoptosis					734:742	apoptosis	734:742	apoptosis of damaged Schwann cells	734:767	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	3	28	theme	sustained	600:608	arg1	effects					626:632	sustained neuroprotective effects	600:632	sustained neuroprotective effects on peripheral nerves	600:653	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	1	29	theme	chitosan	214:221	arg1	scaffold					223:230	a warp-knitted chitosan scaffold	199:230	a warp-knitted chitosan scaffold	199:230	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	2	30	theme	NS-chitosan	482:492	arg1	fibers					494:499	NS-chitosan fibers	482:499	NS-chitosan fibers	482:499	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	4	31	theme	equal	1011:1015	arg1	efficacy					1002:1009	regenerative efficacy	989:1009	regenerative efficacy equal to that of an autograft	989:1039	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	5	32	theme	good	1168:1171	arg1	properties					1198:1207	good mechanical and bioactive properties	1168:1207	good mechanical and bioactive properties	1168:1207	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	3	33	theme	neuroprotective	610:624	arg1	effects					626:632	sustained neuroprotective effects	600:632	sustained neuroprotective effects on peripheral nerves	600:653	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	2	34	theme	mechanical	413:422	arg1	support					424:430	appropriate mechanical support	401:430	appropriate mechanical support	401:430	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	5	35	theme	mechanical	1173:1182	arg1	properties					1198:1207	good mechanical and bioactive properties	1168:1207	good mechanical and bioactive properties	1168:1207	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	5	36	theme	warp-knitted	1112:1123	arg1	construct					1130:1138	a warp-knitted tube construct	1110:1138	a warp-knitted tube construct	1110:1138	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	5	37	contain	had	1164:1166	arg1	conduit					1097:1103	the chitosan/NS-chitosan conduit	1072:1103	the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber	1072:1162	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	5	37	contain	had	1164:1166	arg2	properties					1198:1207	good mechanical and bioactive properties	1168:1207	good mechanical and bioactive properties	1168:1207	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	1	38	theme	nerve	327:331	arg1	defect					333:338	a 10-mm nerve defect	319:338	a 10-mm nerve defect in rats	319:346	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	4	39	theme	nerve	968:972	arg1	model					974:978	a damaged 10-mm peripheral nerve model	941:978	a damaged 10-mm peripheral nerve model	941:978	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	5	40	theme	tube	1125:1128	arg1	construct					1130:1138	a warp-knitted tube construct	1110:1138	a warp-knitted tube construct	1110:1138	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	5	41	with	conduit	1097:1103	arg1	construct					1130:1138	a warp-knitted tube construct	1110:1138	a warp-knitted tube construct	1110:1138	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	5	41	with	conduit	1097:1103	arg1	fiber					1158:1162	aligned inner fiber	1144:1162	aligned inner fiber	1144:1162	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	4	42	theme	chitosan/NS-chitosan	827:846	arg1	conduit					848:854	The multichannel chitosan/NS-chitosan conduit	810:854	The multichannel chitosan/NS-chitosan conduit	810:854	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	3	43	theme	peripheral	637:646	arg1	nerves					648:653	peripheral nerves	637:653	peripheral nerves	637:653	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	5	44	theme	aligned	1144:1150	arg1	fiber					1158:1162	aligned inner fiber	1144:1162	aligned inner fiber	1144:1162	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	4	45	theme	multichannel	814:825	arg1	conduit					848:854	The multichannel chitosan/NS-chitosan conduit	810:854	The multichannel chitosan/NS-chitosan conduit	810:854	The multichannel chitosan/NS-chitosan conduit represented a histologically and functionally successful nerve reconstruction across a damaged 10-mm peripheral nerve model, showing regenerative efficacy equal to that of an autograft.					
36446493	0	46	theme	nerve	70:74	arg1	regeneration					76:87	peripheral nerve regeneration	59:87	peripheral nerve regeneration	59:87	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	3	47	theme	cellular	686:693	arg1	migration					695:703	cellular migration	686:703	cellular migration	686:703	These fibers degraded slowly for over 90 days and exerted sustained neuroprotective effects on peripheral nerves through their ability to drive cellular migration, promote survival, and block apoptosis of damaged Schwann cells through the Bcl-2/Bax/caspase-3 pathway.					
36446493	5	48	theme	chitosan/NS-chitosan	1076:1095	arg1	conduit					1097:1103	the chitosan/NS-chitosan conduit	1072:1103	the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber	1072:1162	The results demonstrated that the chitosan/NS-chitosan conduit with a warp-knitted tube construct and aligned inner fiber had good mechanical and bioactive properties for nerve repair.					
36446493	1	49	theme	oriented	247:254	arg1	fibers					290:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	0	50	theme	peripheral	59:68	arg1	regeneration					76:87	peripheral nerve regeneration	59:87	peripheral nerve regeneration	59:87	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36446493	2	51	with	pipeline	387:394	arg1	support					424:430	appropriate mechanical support	401:430	appropriate mechanical support	401:430	This study confirmed that an external pipeline with appropriate mechanical support was obtained by warp knitting techniques and that NS-chitosan fibers were not toxic to L-929 and PC-12 cells.					
36446493	1	52	theme	N-succinyl-chitosan	256:274	arg1	fibers					290:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	internally oriented N-succinyl-chitosan (NS-chitosan) fibers	236:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	1	53	theme	chitosan-based	133:146	arg1	conduit					177:183	a chitosan-based composite multichannel nerve conduit	131:183	a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers	131:295	In this study, a chitosan-based composite multichannel nerve conduit consisting of a warp-knitted chitosan scaffold and internally oriented N-succinyl-chitosan (NS-chitosan) fibers was applied to bridge a 10-mm nerve defect in rats.					
36446493	0	54	theme	Schwann	93:99	arg1	survival					106:113	Schwann cell survival	93:113	Schwann cell survival	93:113	Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival.					
36746590	1	0	theme	nanostructured	138:151	arg1	aerogels					160:167	nanostructured pectin aerogels	138:167	nanostructured pectin aerogels	138:167	In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions.					
36746590	0	1	theme	composition	67:77	arg1	Effect					50:55	Effect	50:55	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.	0:122	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	5	2	theme	low	878:880	arg1	0.025-0.10 g/cm3					896:911	0.025-0.10 g/cm3	896:911	0.025-0.10 g/cm3	896:911	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	2	theme	low	878:880	arg1	density					887:893	low bulk density	878:893	low bulk density (0.025-0.10 g/cm3)	878:912	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	1	3	theme	pectin	153:158	arg1	aerogels					160:167	nanostructured pectin aerogels	138:167	nanostructured pectin aerogels	138:167	In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions.					
36746590	4	4	theme	hydrogels	757:765	arg1	production					743:752	the production	739:752	the production of hydrogels and subsequent aerogels	739:789	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	2	5	theme	available	291:299	arg1	pectins					308:314	three commercially available citrus pectins	272:314	three commercially available citrus pectins	272:314	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	0	6	theme	aerogel	82:88	arg1	structure					90:98	aerogel structure	82:98	aerogel structure	82:98	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	0	7	from	Effect	50:55	arg1	structure					90:98	aerogel structure	82:98	aerogel structure	82:98	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	0	7	from	Effect	50:55	arg1	properties					112:121	release properties	104:121	release properties	104:121	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	2	8	theme	modified	359:366	arg1	WRP					392:394	WRP	392:394	WRP	392:394	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	2	8	theme	modified	359:366	arg1	pectin					384:389	an in-house produced and enzymatically modified watermelon rind pectin	320:389	an in-house produced and enzymatically modified watermelon rind pectin (WRP)	320:395	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	6	9	theme	pectin	995:1000	arg1	concentration					1002:1014	the pectin concentration	991:1014	the pectin concentration	991:1014	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	0	10	theme	release	104:110	arg1	properties					112:121	release properties	104:121	release properties	104:121	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	6	11	theme	vanillin	1037:1044	arg1	loading					1046:1052	vanillin loading	1037:1052	vanillin loading in aerogels and its release profile	1037:1088	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	5	12	theme	surface	845:851	arg1	areas					853:857	high specific surface areas	831:857	high specific surface areas (468-584 m2/g)	831:872	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	12	theme	surface	845:851	arg1	468-584 m2/g					860:871	468-584 m2/g	860:871	468-584 m2/g	860:871	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	13	theme	bulk	882:885	arg1	0.025-0.10 g/cm3					896:911	0.025-0.10 g/cm3	896:911	0.025-0.10 g/cm3	896:911	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	13	theme	bulk	882:885	arg1	density					887:893	low bulk density	878:893	low bulk density (0.025-0.10 g/cm3)	878:912	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	3	14	theme	potential	515:523	arg1	application					525:535	its potential application	511:535	its potential application as a delivery system	511:556	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	6	15	theme	release	1074:1080	arg1	profile					1082:1088	its release profile	1070:1088	its release profile	1070:1088	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	7	16	theme	biomedical	1305:1314	arg1	areas					1316:1320	food and biomedical areas	1296:1320	food and biomedical areas	1296:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	0	17	theme	aerogel	13:19	arg1	particles					21:29	Pectin-based aerogel particles	0:29	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.	0:122	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	7	18	theme	active	1237:1242	arg1	compounds					1244:1252	active compounds	1237:1252	active compounds which might have potential application in food and biomedical areas	1237:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	0	19	theme	Pectin-based	0:11	arg1	particles					21:29	Pectin-based aerogel particles	0:29	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.	0:122	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	6	20	from	loading	1046:1052	arg1	aerogels					1057:1064	aerogels	1057:1064	aerogels	1057:1064	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	6	20	from	loading	1046:1052	arg1	profile					1082:1088	its release profile	1070:1088	its release profile	1070:1088	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	4	21	theme	branching	678:686	arg1	degree					688:693	branching degree	678:693	branching degree of the pectin samples	678:715	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	5	22	theme	developed	796:804	arg1	particles					814:822	The developed aerogel particles	792:822	The developed aerogel particles	792:822	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	2	23	theme	citrus	301:306	arg1	pectins					308:314	three commercially available citrus pectins	272:314	three commercially available citrus pectins	272:314	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	3	24	theme	structure	441:449	arg1	effect					422:427	the effect	418:427	the effect of pectin's structure and composition on the aerogel properties	418:491	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	5	25	theme	aerogel	806:812	arg1	particles					814:822	The developed aerogel particles	792:822	The developed aerogel particles	792:822	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	6	26	theme	aerogel	943:949	arg1	formation					951:959	aerogel formation	943:959	aerogel formation	943:959	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	7	27	contain	have	1266:1269	arg2	application					1281:1291	potential application	1271:1291	potential application	1271:1291	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	7	27	contain	have	1266:1269	arg1	compounds					1244:1252	active compounds	1237:1252	active compounds which might have potential application in food and biomedical areas	1237:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	3	28	theme	delivery	542:549	arg1	system					551:556	a delivery system	540:556	a delivery system	540:556	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	1	29	theme	sol-gel	189:195	arg1	process					197:203	a sol-gel process	187:203	a sol-gel process	187:203	In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions.					
36746590	3	30	theme	aerogel	474:480	arg1	properties					482:491	the aerogel properties	470:491	the aerogel properties	470:491	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	5	31	theme	high	831:834	arg1	areas					853:857	high specific surface areas	831:857	high specific surface areas (468-584 m2/g)	831:872	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	31	theme	high	831:834	arg1	468-584 m2/g					860:871	468-584 m2/g	860:871	468-584 m2/g	860:871	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	7	32	theme	food	1296:1299	arg1	areas					1316:1320	food and biomedical areas	1296:1320	food and biomedical areas	1296:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	4	33	theme	molecular	631:639	arg1	weight					641:646	the molecular weight	627:646	the molecular weight	627:646	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	0	34	theme	drug	35:38	arg1	delivery					40:47	drug delivery	35:47	drug delivery	35:47	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	5	35	theme	specific	836:843	arg1	areas					853:857	high specific surface areas	831:857	high specific surface areas (468-584 m2/g)	831:872	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	5	35	theme	specific	836:843	arg1	468-584 m2/g					860:871	468-584 m2/g	860:871	468-584 m2/g	860:871	The developed aerogel particles showed high specific surface areas (468-584 m2/g) and low bulk density (0.025-0.10 g/cm3).					
36746590	6	36	theme	shrinkage	919:927	arg1	effect					929:934	The shrinkage effect	915:934	The shrinkage effect during aerogel formation	915:959	The shrinkage effect during aerogel formation was significantly affected by the pectin concentration and structure, while vanillin loading in aerogels and its release profile was also seen to be influenced by the affinity between pectin and vanillin.					
36746590	7	37	theme	compounds	1244:1252	arg1	carrier					1226:1232	a carrier	1224:1232	a carrier of active compounds which might have potential application in food and biomedical areas	1224:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	7	37	theme	compounds	1244:1252	arg1	interest					1205:1212	the interest	1201:1212	the interest of WRP	1201:1219	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	2	38	theme	produced	332:339	arg1	WRP					392:394	WRP	392:394	WRP	392:394	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	2	38	theme	produced	332:339	arg1	pectin					384:389	an in-house produced and enzymatically modified watermelon rind pectin	320:389	an in-house produced and enzymatically modified watermelon rind pectin (WRP)	320:395	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	4	39	theme	samples	709:715	arg1	degree					688:693	branching degree	678:693	branching degree of the pectin samples	678:715	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	39	theme	samples	709:715	arg1	degree					649:654	degree	649:654	degree of esterification	649:672	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	39	theme	samples	709:715	arg1	weight					641:646	the molecular weight	627:646	the molecular weight	627:646	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	40	theme	esterification	659:672	arg1	degree					688:693	branching degree	678:693	branching degree of the pectin samples	678:715	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	40	theme	esterification	659:672	arg1	degree					649:654	degree	649:654	degree of esterification	649:672	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	40	theme	esterification	659:672	arg1	weight					641:646	the molecular weight	627:646	the molecular weight	627:646	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	2	41	theme	in-house	323:330	arg1	WRP					392:394	WRP	392:394	WRP	392:394	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	2	41	theme	in-house	323:330	arg1	pectin					384:389	an in-house produced and enzymatically modified watermelon rind pectin	320:389	an in-house produced and enzymatically modified watermelon rind pectin (WRP)	320:395	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	1	42	theme	subsequent	209:218	arg1	drying					220:225	subsequent drying	209:225	subsequent drying	209:225	In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions.					
36746590	0	43	dep	particles	21:29	arg1	Effect					50:55	Effect	50:55	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.	0:122	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	4	44	theme	main	726:729	arg1	role					731:734	a main role	724:734	a main role	724:734	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	4	45	theme	pectin	702:707	arg1	samples					709:715	the pectin samples	698:715	the pectin samples	698:715	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	3	46	theme	composition	455:465	arg1	effect					422:427	the effect	418:427	the effect of pectin's structure and composition on the aerogel properties	418:491	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	0	47	theme	pectin	60:65	arg1	composition					67:77	pectin composition	60:77	pectin composition	60:77	Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.					
36746590	4	48	theme	aerogels	782:789	arg1	production					743:752	the production	739:752	the production of hydrogels and subsequent aerogels	739:789	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	7	49	theme	potential	1271:1279	arg1	application					1281:1291	potential application	1271:1291	potential application	1271:1291	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	2	50	theme	rind	379:382	arg1	WRP					392:394	WRP	392:394	WRP	392:394	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	2	50	theme	rind	379:382	arg1	pectin					384:389	an in-house produced and enzymatically modified watermelon rind pectin	320:389	an in-house produced and enzymatically modified watermelon rind pectin (WRP)	320:395	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	4	51	theme	subsequent	771:780	arg1	aerogels					782:789	subsequent aerogels	771:789	subsequent aerogels	771:789	Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels.					
36746590	3	52	from	effect	422:427	arg1	properties					482:491	the aerogel properties	470:491	the aerogel properties	470:491	Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin.					
36746590	2	53	theme	watermelon	368:377	arg1	WRP					392:394	WRP	392:394	WRP	392:394	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	2	53	theme	watermelon	368:377	arg1	pectin					384:389	an in-house produced and enzymatically modified watermelon rind pectin	320:389	an in-house produced and enzymatically modified watermelon rind pectin (WRP)	320:395	To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared.					
36746590	7	54	theme	WRP	1217:1219	arg1	carrier					1226:1232	a carrier	1224:1232	a carrier of active compounds which might have potential application in food and biomedical areas	1224:1320	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	7	54	theme	WRP	1217:1219	arg1	interest					1205:1212	the interest	1201:1212	the interest of WRP	1201:1219	Furthermore, the results highlight the interest of WRP as a carrier of active compounds which might have potential application in food and biomedical areas, among others.					
36746590	1	55	theme	supercritical	233:245	arg1	conditions					247:256	supercritical conditions	233:256	supercritical conditions	233:256	In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions.					
36413305	8	0	theme	bonds	1128:1132	arg1	types					1048:1052	all identified types	1033:1052	all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1033:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	5	1	theme	molecular	554:562	arg1	calculations					573:584	molecular dynamics calculations	554:584	molecular dynamics calculations of HA-collagen type II interactions with hyaluronan	554:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	1	2	theme	numerous	161:168	arg1	applications					181:192	numerous biomedical applications	161:192	numerous biomedical applications	161:192	Hyaluronan-collagen composites have been employed in numerous biomedical applications.					
36413305	13	3	theme	aqueous	1710:1716	arg1	environment					1718:1728	the aqueous environment	1706:1728	the aqueous environment	1706:1728	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	11	4	theme	attachment	1534:1543	arg1	position					1545:1552	the hydroxyl group attachment position	1515:1552	the hydroxyl group attachment position	1515:1552	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	11	5	theme	results	1446:1452	arg1	comparison					1428:1437	A comparison	1426:1437	A comparison of the results obtained for 3 and 4 hydroxylation of proline	1426:1498	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	8	6	theme	hydrogen	1119:1126	arg1	bonds					1128:1132	hydrogen bonds	1119:1132	hydrogen bonds	1119:1132	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	11	7	theme	complex	1576:1582	arg1	stabilization					1584:1596	complex stabilization	1576:1596	complex stabilization	1576:1596	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	1	8	theme	biomedical	170:179	arg1	applications					181:192	numerous biomedical applications	161:192	numerous biomedical applications	161:192	Hyaluronan-collagen composites have been employed in numerous biomedical applications.					
36413305	8	9	theme	water	1101:1105	arg1	bridges					1107:1113	water bridges	1101:1113	water bridges	1101:1113	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	12	10	theme	stronger	1619:1626	arg1	affinity					1628:1635	a slightly stronger affinity	1608:1635	a slightly stronger affinity	1608:1635	However, a slightly stronger affinity was observed for 4 hydroxylation.					
36413305	0	11	theme	dynamics	92:99	arg1	study					101:105	a molecular dynamics study	80:105	a molecular dynamics study	80:105	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	5	12	theme	II	606:607	arg1	interactions					609:620	HA-collagen type II interactions	589:620	HA-collagen type II interactions with hyaluronan	589:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	8	13	theme	forces	1067:1072	arg1	types					1048:1052	all identified types	1033:1052	all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1033:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	6	14	theme	hydroxyl	774:781	arg1	groups					783:788	hydroxyl groups	774:788	hydroxyl groups attached to proline moieties	774:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	0	15	theme	molecular	82:90	arg1	dynamics					92:99	molecular dynamics	82:99	a molecular dynamics study	80:105	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	0	16	dep	study	101:105	arg1	interactions					28:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	0	16	dep	study	101:105	arg1	effect					47:52	the effect	43:52	the effect of proline hydroxylation	43:77	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	4	17	theme	important	436:444	arg1	factors					446:452	the important factors	432:452	the important factors	432:452	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	2	18	theme	function	318:325	arg1	treatment					335:343	the treatment	331:343	the treatment of joint diseases	331:361	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	2	18	theme	function	318:325	arg1	context					291:297	the context	287:297	the context of joint cartilage function	287:325	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	7	19	theme	collagen-hyaluronan	931:949	arg1	complex					951:957	the collagen-hyaluronan complex	927:957	the collagen-hyaluronan complex	927:957	It was established that the hydroxyproline/proline ratio affects both structural and energetic features of the collagen-hyaluronan complex.					
36413305	11	20	theme	group	1528:1532	arg1	position					1545:1552	the hydroxyl group attachment position	1515:1552	the hydroxyl group attachment position	1515:1552	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	11	21	theme	proline	1492:1498	arg1	hydroxylation					1475:1487	3 and 4 hydroxylation	1467:1487	3 and 4 hydroxylation of proline	1467:1498	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	4	22	theme	proline	486:492	arg1	factors					446:452	the important factors	432:452	the important factors	432:452	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	4	22	theme	proline	486:492	arg1	ratio					461:465	the ratio	457:465	the ratio of 3- or 4-hydroxy proline to proline residues	457:512	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	4	22	theme	proline	486:492	arg1	One					425:427	One	425:427	One	425:427	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	8	23	theme	hydrophobic	1075:1085	arg1	interactions					1087:1098	hydrophobic interactions	1075:1098	hydrophobic interactions	1075:1098	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	2	24	theme	cartilage	308:316	arg1	function					318:325	joint cartilage function	302:325	joint cartilage function	302:325	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	7	25	theme	complex	951:957	arg1	features					915:922	both structural and energetic features	885:922	both structural and energetic features of the collagen-hyaluronan complex	885:957	It was established that the hydroxyproline/proline ratio affects both structural and energetic features of the collagen-hyaluronan complex.					
36413305	13	26	from	effect	1696:1701	arg1	stability					1765:1773	the collagen-hyaluronan complex stability	1733:1773	the collagen-hyaluronan complex stability	1733:1773	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	13	27	theme	free	1824:1827	arg1	energy					1829:1834	the free energy	1820:1834	the free energy of solvation	1820:1847	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	13	28	theme	enthalpic	1780:1788	arg1	contributions					1803:1815	the enthalpic and entropic contributions	1776:1815	the enthalpic and entropic contributions to the free energy of solvation	1776:1847	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	5	29	theme	type	601:604	arg1	interactions					609:620	HA-collagen type II interactions	589:620	HA-collagen type II interactions with hyaluronan	589:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	2	30	theme	joint	302:306	arg1	function					318:325	joint cartilage function	302:325	joint cartilage function	302:325	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	2	31	from	important	274:282	arg1	treatment					335:343	the treatment	331:343	the treatment of joint diseases	331:361	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	2	31	from	important	274:282	arg1	context					291:297	the context	287:297	the context of joint cartilage function	287:325	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	0	32	theme	type	9:12	arg1	interactions					28:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	4	33	theme	proline	497:503	arg1	residues					505:512	proline residues	497:512	proline residues	497:512	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	0	34	theme	hydroxylation	65:77	arg1	effect					47:52	the effect	43:52	the effect of proline hydroxylation	43:77	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	2	35	theme	joint	348:352	arg1	diseases					354:361	joint diseases	348:361	joint diseases	348:361	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	10	36	theme	binding	1376:1382	arg1	energy					1389:1394	the binding free energy	1372:1394	the binding free energy	1372:1394	This is illustrated by the linear correlation between the binding free energy and the hydroxylation degree.					
36413305	0	37	theme	Collagen	0:7	arg1	interactions					28:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	5	38	with	interactions	609:620	arg1	hyaluronan					627:636	hyaluronan	627:636	hyaluronan	627:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	13	39	theme	entropic	1794:1801	arg1	contributions					1803:1815	the enthalpic and entropic contributions	1776:1815	the enthalpic and entropic contributions to the free energy of solvation	1776:1847	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	5	40	theme	interactions	609:620	arg1	calculations					573:584	molecular dynamics calculations	554:584	molecular dynamics calculations of HA-collagen type II interactions with hyaluronan	554:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	7	41	theme	energetic	905:913	arg1	features					915:922	both structural and energetic features	885:922	both structural and energetic features of the collagen-hyaluronan complex	885:957	It was established that the hydroxyproline/proline ratio affects both structural and energetic features of the collagen-hyaluronan complex.					
36413305	3	42	theme	collagen	400:407	arg1	affinity					388:395	the affinity	384:395	the affinity of collagen for hyaluronan	384:422	Many factors affect the affinity of collagen for hyaluronan.					
36413305	13	43	theme	collagen-hyaluronan	1737:1755	arg1	stability					1765:1773	the collagen-hyaluronan complex stability	1733:1773	the collagen-hyaluronan complex stability	1733:1773	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	8	44	theme	bridges	1107:1113	arg1	types					1048:1052	all identified types	1033:1052	all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1033:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	10	45	theme	hydroxylation	1404:1416	arg1	degree					1418:1423	the hydroxylation degree	1400:1423	the hydroxylation degree	1400:1423	This is illustrated by the linear correlation between the binding free energy and the hydroxylation degree.					
36413305	6	46	theme	collagen	728:735	arg1	structures					737:746	collagen structures	728:746	collagen structures	728:746	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	0	47	theme	II-hyaluronan	14:26	arg1	interactions					28:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions	0:39	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	7	48	theme	hydroxyproline/proline	848:869	arg1	ratio					871:875	the hydroxyproline/proline ratio	844:875	the hydroxyproline/proline ratio	844:875	It was established that the hydroxyproline/proline ratio affects both structural and energetic features of the collagen-hyaluronan complex.					
36413305	13	49	theme	complex	1757:1763	arg1	stability					1765:1773	the collagen-hyaluronan complex stability	1733:1773	the collagen-hyaluronan complex stability	1733:1773	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	11	50	theme	hydroxyl	1519:1526	arg1	position					1545:1552	the hydroxyl group attachment position	1515:1552	the hydroxyl group attachment position	1515:1552	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	7	51	theme	structural	890:899	arg1	features					915:922	both structural and energetic features	885:922	both structural and energetic features of the collagen-hyaluronan complex	885:957	It was established that the hydroxyproline/proline ratio affects both structural and energetic features of the collagen-hyaluronan complex.					
36413305	11	52	theme	minor	1562:1566	arg1	role					1568:1571	a minor role	1560:1571	a minor role	1560:1571	A comparison of the results obtained for 3 and 4 hydroxylation of proline indicates that the hydroxyl group attachment position plays a minor role in complex stabilization.					
36413305	2	53	from	context	291:297	arg1	important					274:282	important	274:282	important	274:282	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	8	54	theme	interactions	1087:1098	arg1	types					1048:1052	all identified types	1033:1052	all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1033:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	9	55	from	increase	1204:1211	arg1	ratio					1243:1247	the hydroxyproline/proline ratio	1216:1247	the hydroxyproline/proline ratio	1216:1247	Importantly, an increase in the hydroxyproline/proline ratio in the collagen chain increases the binding affinity for hyaluronan.					
36413305	9	55	from	increase	1204:1211	arg1	chain					1265:1269	the collagen chain	1252:1269	the collagen chain	1252:1269	Importantly, an increase in the hydroxyproline/proline ratio in the collagen chain increases the binding affinity for hyaluronan.					
36413305	5	56	theme	dynamics	564:571	arg1	calculations					573:584	molecular dynamics calculations	554:584	molecular dynamics calculations of HA-collagen type II interactions with hyaluronan	554:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	5	57	from	calculations	573:584	arg1	results					541:547	the results	537:547	the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan	537:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	10	58	theme	free	1384:1387	arg1	energy					1389:1394	the binding free energy	1372:1394	the binding free energy	1372:1394	This is illustrated by the linear correlation between the binding free energy and the hydroxylation degree.					
36413305	9	59	theme	binding	1285:1291	arg1	affinity					1293:1300	the binding affinity	1281:1300	the binding affinity for hyaluronan	1281:1315	Importantly, an increase in the hydroxyproline/proline ratio in the collagen chain increases the binding affinity for hyaluronan.					
36413305	1	60	theme	Hyaluronan-collagen	108:126	arg1	composites					128:137	Hyaluronan-collagen composites	108:137	Hyaluronan-collagen composites	108:137	Hyaluronan-collagen composites have been employed in numerous biomedical applications.					
36413305	6	61	theme	applied	643:649	arg1	protocol					651:658	The applied protocol	639:658	The applied protocol	639:658	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	13	62	theme	environment	1718:1728	arg1	effect					1696:1701	the effect	1692:1701	the effect of the aqueous environment on the collagen-hyaluronan complex stability	1692:1773	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	9	63	theme	hydroxyproline/proline	1220:1241	arg1	ratio					1243:1247	the hydroxyproline/proline ratio	1216:1247	the hydroxyproline/proline ratio	1216:1247	Importantly, an increase in the hydroxyproline/proline ratio in the collagen chain increases the binding affinity for hyaluronan.					
36413305	6	64	theme	complexes	706:714	arg1	docking					669:675	docking	669:675	docking	669:675	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	6	64	theme	complexes	706:714	arg1	optimization					690:701	geometry optimization	681:701	geometry optimization	681:701	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	4	65	theme	factors	446:452	arg1	factors					446:452	the important factors	432:452	the important factors	432:452	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	4	65	theme	factors	446:452	arg1	ratio					461:465	the ratio	457:465	the ratio of 3- or 4-hydroxy proline to proline residues	457:512	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	4	65	theme	factors	446:452	arg1	One					425:427	One	425:427	One	425:427	One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues.					
36413305	5	66	theme	HA-collagen	589:599	arg1	interactions					609:620	HA-collagen type II interactions	589:620	HA-collagen type II interactions with hyaluronan	589:636	This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan.					
36413305	13	67	theme	solvation	1839:1847	arg1	energy					1829:1834	the free energy	1820:1834	the free energy of solvation	1820:1847	In order to evaluate the effect of the aqueous environment on the collagen-hyaluronan complex stability, the enthalpic and entropic contributions to the free energy of solvation were analyzed.					
36413305	8	68	theme	molecular	1057:1065	arg1	forces					1067:1072	molecular forces	1057:1072	molecular forces	1057:1072	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	6	69	theme	proline	802:808	arg1	moieties					810:817	proline moieties	802:817	proline moieties	802:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	9	70	theme	collagen	1256:1263	arg1	chain					1265:1269	the collagen chain	1252:1269	the collagen chain	1252:1269	Importantly, an increase in the hydroxyproline/proline ratio in the collagen chain increases the binding affinity for hyaluronan.					
36413305	8	71	theme	types	1048:1052	arg1	number					1023:1028	the number	1019:1028	the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1019:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	2	72	theme	diseases	354:361	arg1	treatment					335:343	the treatment	331:343	the treatment of joint diseases	331:361	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	2	72	theme	diseases	354:361	arg1	context					291:297	the context	287:297	the context of joint cartilage function	287:325	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
36413305	6	73	theme	different	753:761	arg1	numbers					763:769	different numbers	753:769	different numbers of hydroxyl groups attached to proline moieties	753:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	3	74	theme	Many	364:367	arg1	factors					369:375	Many factors	364:375	Many factors	364:375	Many factors affect the affinity of collagen for hyaluronan.					
36413305	10	75	theme	linear	1345:1350	arg1	correlation					1352:1362	the linear correlation	1341:1362	the linear correlation between the binding free energy and the hydroxylation degree	1341:1423	This is illustrated by the linear correlation between the binding free energy and the hydroxylation degree.					
36413305	8	76	theme	identified	1037:1046	arg1	types					1048:1052	all identified types	1033:1052	all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan	1033:1185	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	8	77	theme	Proline	960:966	arg1	hydroxylation					968:980	Proline hydroxylation	960:980	Proline hydroxylation	960:980	Proline hydroxylation was found to significantly influence the number of all identified types of molecular forces, hydrophobic interactions, water bridges and hydrogen bonds, which can be formed between collagen and hyaluronan.					
36413305	6	78	theme	geometry	681:688	arg1	optimization					690:701	geometry optimization	681:701	geometry optimization	681:701	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	0	79	theme	proline	57:63	arg1	hydroxylation					65:77	proline hydroxylation	57:77	proline hydroxylation	57:77	Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.					
36413305	6	80	theme	groups	783:788	arg1	numbers					763:769	different numbers	753:769	different numbers of hydroxyl groups attached to proline moieties	753:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	6	81	attach	attached	790:797	arg1	moieties					810:817	proline moieties	802:817	proline moieties	802:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	6	81	attach	attached	790:797	arg2	groups					783:788	hydroxyl groups	774:788	hydroxyl groups attached to proline moieties	774:817	The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydroxyl groups attached to proline moieties.					
36413305	2	82	from	treatment	335:343	arg1	important					274:282	important	274:282	important	274:282	Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases.					
37062378	0	0	theme	strain	97:102	arg1	sensor					104:109	flexible strain sensor	88:109	flexible strain sensor	88:109	Graphene composite paper synergized with micro/nanocellulose-fiber and silk fibroin for flexible strain sensor.					
37062378	2	1	with	paper	366:370	arg1	SF					422:423	SF	422:423	SF	422:423	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	1	with	paper	366:370	arg1	fibers					397:402	micro/nanocellulose fibers	377:402	micro/nanocellulose fibers	377:402	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	1	with	paper	366:370	arg1	fibroin					413:419	silk fibroin	408:419	silk fibroin (SF)	408:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	1	2	theme	paper	176:180	arg1	fabrication					116:126	The fabrication	112:126	The fabrication of uniform and strong graphene-based conductive paper	112:180	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	3	3	theme	binding	778:784	arg1	agents					786:791	interfacial binding agents	766:791	interfacial binding agents	766:791	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	0	4	theme	flexible	88:95	arg1	sensor					104:109	flexible strain sensor	88:109	flexible strain sensor	88:109	Graphene composite paper synergized with micro/nanocellulose-fiber and silk fibroin for flexible strain sensor.					
37062378	3	5	theme	strength	660:667	arg1	combination					593:603	ideal combination	587:603	ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively	587:805	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	6	theme	cellulose	497:505	arg1	CMFs					520:523	CMFs	520:523	CMFs	520:523	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	6	theme	cellulose	497:505	arg1	microfibers					507:517	cellulose microfibers	497:517	cellulose microfibers (CMFs)	497:524	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	5	7	theme	joints	1004:1009	arg1	strength					938:945	a tensile strength	928:945	a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance	928:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	5	8	theme	tensile	930:936	arg1	strength					938:945	a tensile strength	928:945	a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance	928:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	3	9	theme	microfibers	507:517	arg1	effects					486:492	The synergistic effects	470:492	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF	470:560	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	2	10	theme	dispersing	289:298	arg1	effect					300:305	good dispersing effect	284:305	good dispersing effect of nanocellulose	284:322	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	4	11	theme	CMFs	896:899	arg1	surface					885:891	the surface	881:891	the surface of CMFs	881:899	Extraordinarily, by adding SF, graphene nanosheets are tightly coated on the surface of CMFs.					
37062378	3	12	theme	cellulose	527:535	arg1	CNFs					549:552	CNFs	549:552	CNFs	549:552	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	12	theme	cellulose	527:535	arg1	nanofibers					537:546	cellulose nanofibers	527:546	cellulose nanofibers (CNFs)	527:553	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	2	13	theme	good	284:287	arg1	effect					300:305	good dispersing effect	284:305	good dispersing effect of nanocellulose	284:322	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	14	theme	high	325:328	arg1	graphene					338:345	high content graphene	325:345	high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF)	325:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	14	theme	high	325:328	arg1	%					353:353	50 wt%	348:353	50 wt%	348:353	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	7	15	theme	devices	1261:1267	arg1	development					1211:1221	the development	1207:1221	the development of smart clothing wearable biosensing devices	1207:1267	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	6	16	theme	bending	1142:1148	arg1	test					1150:1153	the cyclic elbow bending test	1125:1153	the cyclic elbow bending test	1125:1153	Additionally, it is found that CMFs can hinder the micro-cracks from propagating during the cyclic elbow bending test.					
37062378	3	17	theme	interfacial	766:776	arg1	agents					786:791	interfacial binding agents	766:791	interfacial binding agents	766:791	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	2	18	theme	micro/nanocellulose	377:395	arg1	fibers					397:402	micro/nanocellulose fibers	377:402	micro/nanocellulose fibers	377:402	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	0	19	theme	composite	9:17	arg1	paper					19:23	Graphene composite paper	0:23	Graphene composite paper	0:23	Graphene composite paper synergized with micro/nanocellulose-fiber and silk fibroin for flexible strain sensor.					
37062378	7	20	theme	clothing	1232:1239	arg1	devices					1261:1267	smart clothing wearable biosensing devices	1226:1267	smart clothing wearable biosensing devices	1226:1267	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	5	21	dep	49.29 MPa	950:958	arg1	performance					1024:1034	bend sensing performance	1011:1034	bend sensing performance	1011:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	0	22	theme	Graphene	0:7	arg1	paper					19:23	Graphene composite paper	0:23	Graphene composite paper	0:23	Graphene composite paper synergized with micro/nanocellulose-fiber and silk fibroin for flexible strain sensor.					
37062378	5	23	theme	good	999:1002	arg1	joints					1004:1009	good joints	999:1009	good joints	999:1009	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	2	24	theme	nanocellulose	310:322	arg1	effect					300:305	good dispersing effect	284:305	good dispersing effect of nanocellulose	284:322	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	1	25	theme	easy	204:207	arg1	aggregation					209:219	easy aggregation	204:219	easy aggregation	204:219	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	5	26	theme	resistance	969:978	arg1	strength					938:945	a tensile strength	928:945	a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance	928:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	3	27	theme	nanofibers	537:546	arg1	effects					486:492	The synergistic effects	470:492	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF	470:560	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	7	28	theme	biosensing	1250:1259	arg1	devices					1261:1267	smart clothing wearable biosensing devices	1226:1267	smart clothing wearable biosensing devices	1226:1267	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	3	29	theme	flexibility	608:618	arg1	combination					593:603	ideal combination	587:603	ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively	587:805	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	2	30	dep	graphene	338:345	arg1	paper					366:370	composite paper	356:370	high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF)	325:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	1	31	theme	graphene-based	150:163	arg1	paper					176:180	uniform and strong graphene-based conductive paper	131:180	uniform and strong graphene-based conductive paper	131:180	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	7	32	theme	wearable	1241:1248	arg1	devices					1261:1267	smart clothing wearable biosensing devices	1226:1267	smart clothing wearable biosensing devices	1226:1267	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	2	33	dep	effect	300:305	arg1	basis					275:279	basis	275:279	basis	275:279	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	33	dep	effect	300:305	arg1	the					271:273	the	271:273	the	271:273	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	1	34	theme	poor	225:228	arg1	formability					235:245	poor film formability	225:245	poor film formability	225:245	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	5	35	theme	49.29 MPa	950:958	arg1	strength					938:945	a tensile strength	928:945	a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance	928:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	2	36	theme	silk	408:411	arg1	SF					422:423	SF	422:423	SF	422:423	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	36	theme	silk	408:411	arg1	fibroin					413:419	silk fibroin	408:419	silk fibroin (SF)	408:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	37	theme	casting	454:460	arg1	method					462:467	simple casting method	447:467	simple casting method	447:467	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	5	38	theme	sensing	1016:1022	arg1	performance					1024:1034	bend sensing performance	1011:1034	bend sensing performance	1011:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	1	39	theme	film	230:233	arg1	formability					235:245	poor film formability	225:245	poor film formability	225:245	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	0	40	theme	silk	71:74	arg1	fibroin					76:82	silk fibroin	71:82	silk fibroin	71:82	Graphene composite paper synergized with micro/nanocellulose-fiber and silk fibroin for flexible strain sensor.					
37062378	4	41	theme	graphene	839:846	arg1	nanosheets					848:857	graphene nanosheets	839:857	graphene nanosheets	839:857	Extraordinarily, by adding SF, graphene nanosheets are tightly coated on the surface of CMFs.					
37062378	5	42	theme	39.0-42.1 Ω	983:993	arg1	joints					1004:1009	good joints	999:1009	good joints	999:1009	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	5	42	theme	39.0-42.1 Ω	983:993	arg1	49.29 MPa					950:958	49.29 MPa	950:958	49.29 MPa	950:958	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	5	42	theme	39.0-42.1 Ω	983:993	arg1	resistance					969:978	surface resistance	961:978	surface resistance of 39.0-42.1 Ω	961:993	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	5	43	theme	surface	961:967	arg1	resistance					969:978	surface resistance	961:978	surface resistance of 39.0-42.1 Ω	961:993	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	3	44	theme	synergistic	474:484	arg1	effects					486:492	The synergistic effects	470:492	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF	470:560	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	45	theme	SF	559:560	arg1	effects					486:492	The synergistic effects	470:492	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF	470:560	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	1	46	theme	uniform	131:137	arg1	paper					176:180	uniform and strong graphene-based conductive paper	131:180	uniform and strong graphene-based conductive paper	131:180	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	3	47	theme	forming	721:727	arg1	film					716:719	film forming	716:727	film forming for GNPs, dimensional stability, and interfacial binding agents	716:791	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	48	theme	mechanical	649:658	arg1	strength					660:667	mechanical strength	649:667	mechanical strength	649:667	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	2	49	theme	content	330:336	arg1	graphene					338:345	high content graphene	325:345	high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF)	325:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	2	49	theme	content	330:336	arg1	%					353:353	50 wt%	348:353	50 wt%	348:353	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	3	50	theme	electrical	621:630	arg1	conductivity					632:643	electrical conductivity	621:643	electrical conductivity	621:643	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	3	51	theme	ideal	587:591	arg1	combination					593:603	ideal combination	587:603	ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively	587:805	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	5	52	theme	bend	1011:1014	arg1	performance					1024:1034	bend sensing performance	1011:1034	bend sensing performance	1011:1034	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	1	53	theme	strong	143:148	arg1	paper					176:180	uniform and strong graphene-based conductive paper	131:180	uniform and strong graphene-based conductive paper	131:180	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	7	54	theme	graphene-based	1160:1173	arg1	helpful					1195:1201	helpful	1195:1201	helpful	1195:1201	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	7	54	theme	graphene-based	1160:1173	arg1	paper					1186:1190	The graphene-based conductive paper	1156:1190	The graphene-based conductive paper	1156:1190	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	3	55	theme	conductivity	632:643	arg1	combination					593:603	ideal combination	587:603	ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively	587:805	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
37062378	6	56	theme	elbow	1136:1140	arg1	test					1150:1153	the cyclic elbow bending test	1125:1153	the cyclic elbow bending test	1125:1153	Additionally, it is found that CMFs can hinder the micro-cracks from propagating during the cyclic elbow bending test.					
37062378	2	57	theme	composite	356:364	arg1	paper					366:370	composite paper	356:370	high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF)	325:424	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	7	58	theme	conductive	1175:1184	arg1	helpful					1195:1201	helpful	1195:1201	helpful	1195:1201	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	7	58	theme	conductive	1175:1184	arg1	paper					1186:1190	The graphene-based conductive paper	1156:1190	The graphene-based conductive paper	1156:1190	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	1	59	theme	graphene	250:257	arg1	formability					235:245	poor film formability	225:245	poor film formability	225:245	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	1	59	theme	graphene	250:257	arg1	aggregation					209:219	easy aggregation	204:219	easy aggregation	204:219	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	2	60	theme	simple	447:452	arg1	method					462:467	simple casting method	447:467	simple casting method	447:467	Herein, on the basis of good dispersing effect of nanocellulose, high content graphene (50 wt%) composite paper with micro/nanocellulose fibers and silk fibroin (SF) was manufactured via simple casting method.					
37062378	5	61	theme	composite	906:914	arg1	paper					916:920	The composite paper	902:920	The composite paper	902:920	The composite paper shows a tensile strength of 49.29 MPa, surface resistance of 39.0-42.1 Ω and good joints bend sensing performance.					
37062378	6	62	theme	cyclic	1129:1134	arg1	test					1150:1153	the cyclic elbow bending test	1125:1153	the cyclic elbow bending test	1125:1153	Additionally, it is found that CMFs can hinder the micro-cracks from propagating during the cyclic elbow bending test.					
37062378	1	63	theme	conductive	165:174	arg1	paper					176:180	uniform and strong graphene-based conductive paper	131:180	uniform and strong graphene-based conductive paper	131:180	The fabrication of uniform and strong graphene-based conductive paper is challenging due to easy aggregation and poor film formability of graphene.					
37062378	7	64	theme	smart	1226:1230	arg1	devices					1261:1267	smart clothing wearable biosensing devices	1226:1267	smart clothing wearable biosensing devices	1226:1267	The graphene-based conductive paper is helpful for the development of smart clothing wearable biosensing devices.					
37062378	3	65	theme	dimensional	739:749	arg1	stability					751:759	dimensional stability	739:759	dimensional stability	739:759	The synergistic effects of cellulose microfibers (CMFs), cellulose nanofibers (CNFs) and SF result in the paper with ideal combination of flexibility, electrical conductivity and mechanical strength, where CNFs, CMFs and SF act as dispersing and film forming for GNPs, dimensional stability, and interfacial binding agents, respectively.					
35638522	10	0	theme	buds	1261:1264	arg1	number					1251:1256	the number	1247:1256	the number of buds	1247:1264	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	1	1	theme	bioactive	296:304	arg1	compounds					306:314	other bioactive compounds	290:314	essential oils as well as other bioactive compounds	264:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	2	theme	Ocimum	163:168	arg1	basilicum&lt					170:181	Ocimum basilicum&lt	163:181	&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.	154:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	9	3	used	used	1127:1130	arg2	Test					1112:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	12	4	theme	chlorophyll	1445:1455	arg1	content					1457:1463	chlorophyll content	1445:1463	chlorophyll content as well as Fv/Fm value	1445:1486	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	4	5	theme	NPK	520:522	arg1	Fertilizer					537:546	NPK Slow-Release Fertilizer	520:546	NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates	520:593	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	14	6	theme	further	1861:1867	arg1	insight					1869:1875	further insight	1861:1875	further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil	1861:1965	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	11	7	theme	different	1333:1341	arg1	rates					1343:1347	different rates	1333:1347	different rates	1333:1347	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	3	8	theme	Slow-release	394:405	arg1	fertilizers					407:417	Slow-release fertilizers	394:417	Slow-release fertilizers	394:417	Slow-release fertilizers have been developed to optimize the fertilization of crops.					
35638522	12	9	with	comparison	1491:1500	arg1	treatment					1521:1529	none NPK-SRFS treatment	1507:1529	none NPK-SRFS treatment	1507:1529	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	4	10	theme	Fertilizer	537:546	arg1	effect					510:515	the effect	506:515	the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam	506:687	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	13	11	theme	oil	1632:1634	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	4	12	from	effect	510:515	arg1	growth					598:603	growth	598:603	growth	598:603	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	4	12	from	effect	510:515	arg1	components					630:639	essential oil components	616:639	essential oil components	616:639	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	4	12	from	effect	510:515	arg1	yield					606:610	yield	606:610	yield	606:610	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	0	13	theme	basilicum	87:95	arg1	Basil					73:77	Basil	73:77	Basil (Ocimum basilicum L.)	73:99	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	13	theme	basilicum	87:95	arg1	L					97:97	Ocimum basilicum L.	80:98	Ocimum basilicum L.	80:98	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	1	14	dep	&lt	154:156	arg1	/i&gt					183:187	/i&gt	183:187	&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.	154:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	14	dep	&lt	154:156	arg1	i&gt					158:161	i&gt	158:161	&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.	154:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	14	dep	&lt	154:156	arg1	basilicum&lt					170:181	Ocimum basilicum&lt	163:181	&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.	154:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	14	dep	&lt	154:156	arg1	L.					190:191	L.	190:191	L.	190:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	7	15	with	treatments	962:971	arg1	rates					988:992	different rates	978:992	different rates of NPK-SRFS	978:1004	The experiments were designed in a fully randomized block model, consisting of four treatments with different rates of NPK-SRFS.					
35638522	1	16	theme	crops	253:257	arg1	crops					253:257	the most important crops	234:257	the most important crops with essential oils as well as other bioactive compounds	234:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	16	theme	crops	253:257	arg1	one					227:229	one	227:229	one	227:229	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	3	17	theme	crops	472:476	arg1	fertilization					455:467	the fertilization	451:467	the fertilization of crops	451:476	Slow-release fertilizers have been developed to optimize the fertilization of crops.					
35638522	1	18	dep	Basil	147:151	arg1	&lt					154:156	&lt	154:156	&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.	154:191	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	8	19	theme	m&lt	1061:1064	arg1	area					1051:1054	an area	1048:1054	an area of 8 m&lt;sup&gt;2&lt;/sup&gt;	1048:1085	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	1	20	theme	essential	264:272	arg1	oils					274:277	essential oils	264:277	essential oils as well as other bioactive compounds	264:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	4	21	theme	different	579:587	arg1	rates					589:593	different rates	579:593	different rates	579:593	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	13	22	theme	different	1595:1603	arg1	changes					1605:1611	slightly different changes	1586:1611	slightly different changes in basil essential oil composition	1586:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	5	23	theme	Basil	732:736	arg1	seedlings					738:746	Basil seedlings	732:746	Basil seedlings	732:746	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	14	24	from	influence	1886:1894	arg1	yield					1923:1927	yield	1923:1927	yield	1923:1927	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	24	from	influence	1886:1894	arg1	growth					1915:1920	growth	1915:1920	growth	1915:1920	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	24	from	influence	1886:1894	arg1	components					1947:1956	essential oil components	1933:1956	essential oil components	1933:1956	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	1	25	theme	aromatic	198:205	arg1	&lt					102:104	&lt	102:104	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.)	102:192	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	25	theme	aromatic	198:205	arg1	herb					207:210	an aromatic herb	195:210	an aromatic herb	195:210	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	13	26	from	content	1664:1670	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	2	27	theme	pharmaceutical	346:359	arg1	benefits					361:368	tremendous pharmaceutical benefits	335:368	tremendous pharmaceutical benefits	335:368	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	13	28	theme	different	1563:1571	arg1	rates					1573:1577	different rates	1563:1577	different rates	1563:1577	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	0	29	theme	Oil	54:56	arg1	Composition					58:68	Essential Oil Composition	44:68	Essential Oil Composition	44:68	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	13	30	theme	abundant	1767:1774	arg1	α-trans-Bergamotene					1737:1755	α-trans-Bergamotene	1737:1755	α-trans-Bergamotene	1737:1755	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	30	theme	abundant	1767:1774	arg1	hydrocarbon					1790:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	0	31	from	Effect	0:5	arg1	Growth					26:31	Growth	26:31	Growth	26:31	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	31	from	Effect	0:5	arg1	Composition					58:68	Essential Oil Composition	44:68	Essential Oil Composition	44:68	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	31	from	Effect	0:5	arg1	Yield					34:38	Yield	34:38	Yield	34:38	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	8	32	dep	area	1051:1054	arg1	2&lt					1073:1076	2&lt	1073:1076	an area of 8 m&lt;sup&gt;2&lt;/sup&gt;	1048:1085	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	8	32	dep	area	1051:1054	arg1	sup&gt					1066:1071	sup&gt	1066:1071	an area of 8 m&lt;sup&gt;2&lt;/sup&gt;	1048:1085	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	8	32	dep	area	1051:1054	arg1	/sup&gt					1078:1084	/sup&gt	1078:1084	an area of 8 m&lt;sup&gt;2&lt;/sup&gt;	1048:1085	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	4	33	theme	oil	626:628	arg1	components					630:639	essential oil components	616:639	essential oil components	616:639	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	14	34	theme	oil	1943:1945	arg1	components					1947:1956	essential oil components	1933:1956	essential oil components	1933:1956	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	9	35	theme	=	1160:1160	arg1	p					1158:1158	p = 0.05	1158:1165	p = 0.05	1158:1165	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	9	35	theme	=	1160:1160	arg1	analysis					1148:1155	statistical analysis	1136:1155	statistical analysis (p = 0.05)	1136:1166	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	13	36	theme	NPK-SRFS	1551:1558	arg1	application					1536:1546	The application	1532:1546	The application of NPK-SRFS at different rates	1532:1577	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	8	37	dep	three	1026:1030	arg1	replicates					1032:1041	replicates	1032:1041	replicates	1032:1041	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	1	38	with	crops	253:257	arg1	oils					274:277	essential oils	264:277	essential oils as well as other bioactive compounds	264:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	38	with	crops	253:257	arg1	compounds					306:314	other bioactive compounds	290:314	essential oils as well as other bioactive compounds	264:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	11	39	theme	leaf	1385:1388	arg1	area					1390:1393	leaf area	1385:1393	leaf area	1385:1393	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	5	40	used	used	771:774	arg2	&lt					690:692	&lt	690:692	&lt	690:692	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	40	used	used	771:774	arg2	materials					785:793	plant materials	779:793	plant materials	779:793	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	0	41	theme	NPK-SRFS	10:17	arg1	Effect					0:5	Effect	0:5	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).	0:100	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	2	42	used	used	378:381	arg2	Basil					317:321	Basil	317:321	Basil leaves	317:328	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	9	43	theme	Multiple	1097:1104	arg1	Test					1112:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	10	44	theme	NPK-SRFS	1203:1210	arg1	treatments					1212:1221	All 3 NPK-SRFS treatments	1197:1221	All 3 NPK-SRFS treatments	1197:1221	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	7	45	theme	randomized	919:928	arg1	model					936:940	a fully randomized block model	911:940	a fully randomized block model	911:940	The experiments were designed in a fully randomized block model, consisting of four treatments with different rates of NPK-SRFS.					
35638522	12	46	theme	none	1507:1510	arg1	treatment					1521:1529	none NPK-SRFS treatment	1507:1529	none NPK-SRFS treatment	1507:1529	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	11	47	theme	basil	1402:1406	arg1	height					1374:1379	plant height	1368:1379	plant height	1368:1379	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	11	47	theme	basil	1402:1406	arg1	area					1390:1393	leaf area	1385:1393	leaf area	1385:1393	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	13	48	theme	oxygenated	1710:1719	arg1	monoterpene					1721:1731	the most abundant oxygenated monoterpene	1692:1731	the most abundant oxygenated monoterpene	1692:1731	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	5	49	theme	plant	779:783	arg1	materials					785:793	plant materials	779:793	plant materials	779:793	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	49	theme	plant	779:783	arg1	&lt					690:692	&lt	690:692	&lt	690:692	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	13	50	theme	Methyl	1675:1680	arg1	Chavicol					1682:1689	Methyl Chavicol	1675:1689	Methyl Chavicol	1675:1689	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	12	51	theme	Fv/Fm	1476:1480	arg1	value					1482:1486	Fv/Fm value	1476:1486	chlorophyll content as well as Fv/Fm value	1445:1486	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	1	52	theme	other	290:294	arg1	compounds					306:314	other bioactive compounds	290:314	essential oils as well as other bioactive compounds	264:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	14	53	dep	&lt	1803:1805	arg1	/b&gt					1827:1831	/b&gt	1827:1831	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.	1803:1966	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	53	dep	&lt	1803:1805	arg1	&lt					1823:1825	&lt	1823:1825	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.	1803:1966	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	53	dep	&lt	1803:1805	arg1	Conclusion					1812:1821	Conclusion	1812:1821	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.	1803:1966	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	53	dep	&lt	1803:1805	arg1	b&gt					1807:1810	b&gt	1807:1810	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.	1803:1966	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	54	dep	growth	1915:1920	arg1	the					1911:1913	the	1911:1913	the	1911:1913	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	4	55	theme	Northern	672:679	arg1	Vietnam					681:687	Northern Vietnam	672:687	Northern Vietnam	672:687	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	13	56	from	α-trans-Bergamotene	1737:1755	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	7	57	theme	NPK-SRFS	997:1004	arg1	rates					988:992	different rates	978:992	different rates of NPK-SRFS	978:1004	The experiments were designed in a fully randomized block model, consisting of four treatments with different rates of NPK-SRFS.					
35638522	13	58	theme	essential	1622:1630	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	8	59	contain	had	1022:1024	arg1	treatment					1012:1020	Each treatment	1007:1020	Each treatment	1007:1020	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	8	59	contain	had	1022:1024	arg2	three					1026:1030	three	1026:1030	three	1026:1030	Each treatment had three replicates with an area of 8 m&lt;sup&gt;2&lt;/sup&gt;.					
35638522	12	60	theme	F10	1418:1420	arg1	treatments					1422:1431	F10 treatments	1418:1431	F10 treatments	1418:1431	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	4	61	theme	Slow-Release	524:535	arg1	Fertilizer					537:546	NPK Slow-Release Fertilizer	520:546	NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates	520:593	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	13	62	from	monoterpene	1721:1731	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	2	63	contain	have	330:333	arg1	Basil					317:321	Basil	317:321	Basil leaves	317:328	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	2	63	contain	have	330:333	arg2	benefits					361:368	tremendous pharmaceutical benefits	335:368	tremendous pharmaceutical benefits	335:368	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	1	64	theme	important	243:251	arg1	crops					253:257	the most important crops	234:257	the most important crops with essential oils as well as other bioactive compounds	234:314	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	14	65	theme	present	1838:1844	arg1	study					1846:1850	The present study	1834:1850	The present study	1834:1850	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	7	66	theme	different	978:986	arg1	rates					988:992	different rates	978:992	different rates of NPK-SRFS	978:1004	The experiments were designed in a fully randomized block model, consisting of four treatments with different rates of NPK-SRFS.					
35638522	4	67	from	field	663:667	arg1	Vietnam					681:687	Northern Vietnam	672:687	Northern Vietnam	672:687	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	0	68	theme	Essential	44:52	arg1	Composition					58:68	Essential Oil Composition	44:68	Essential Oil Composition	44:68	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	2	69	dep	Basil	317:321	arg1	leaves					323:328	leaves	323:328	leaves	323:328	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	2	70	theme	tremendous	335:344	arg1	benefits					361:368	tremendous pharmaceutical benefits	335:368	tremendous pharmaceutical benefits	335:368	Basil leaves have tremendous pharmaceutical benefits and are used for foods.					
35638522	14	71	theme	basil	1961:1965	arg1	yield					1923:1927	yield	1923:1927	yield	1923:1927	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	71	theme	basil	1961:1965	arg1	growth					1915:1920	growth	1915:1920	growth	1915:1920	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	14	71	theme	basil	1961:1965	arg1	components					1947:1956	essential oil components	1933:1956	essential oil components	1933:1956	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	0	72	theme	Basil	73:77	arg1	Growth					26:31	Growth	26:31	Growth	26:31	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	72	theme	Basil	73:77	arg1	Composition					58:68	Essential Oil Composition	44:68	Essential Oil Composition	44:68	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	72	theme	Basil	73:77	arg1	Yield					34:38	Yield	34:38	Yield	34:38	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	13	73	theme	sesquiterpene	1776:1788	arg1	α-trans-Bergamotene					1737:1755	α-trans-Bergamotene	1737:1755	α-trans-Bergamotene	1737:1755	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	73	theme	sesquiterpene	1776:1788	arg1	hydrocarbon					1790:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	74	from	rates	1573:1577	arg1	application					1536:1546	The application	1532:1546	The application of NPK-SRFS at different rates	1532:1577	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	0	75	theme	Ocimum	80:85	arg1	Basil					73:77	Basil	73:77	Basil (Ocimum basilicum L.)	73:99	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	0	75	theme	Ocimum	80:85	arg1	L					97:97	Ocimum basilicum L.	80:98	Ocimum basilicum L.	80:98	Effect of NPK-SRFS on the Growth, Yield and Essential Oil Composition of Basil (Ocimum basilicum L.).					
35638522	4	76	theme	essential	616:624	arg1	components					630:639	essential oil components	616:639	essential oil components	616:639	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	14	77	theme	essential	1933:1941	arg1	components					1947:1956	essential oil components	1933:1956	essential oil components	1933:1956	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	13	78	from	changes	1605:1611	arg1	composition					1636:1646	basil essential oil composition	1616:1646	basil essential oil composition	1616:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	11	79	from	rates	1343:1347	arg1	NPK-SRFS					1321:1328	NPK-SRFS	1321:1328	NPK-SRFS at different rates	1321:1347	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	4	80	from	rates	589:593	arg1	Starch					558:563	Starch	558:563	Starch (NPK-SRFS) at different rates	558:593	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	4	80	from	rates	589:593	arg1	NPK-SRFS					566:573	NPK-SRFS	566:573	NPK-SRFS	566:573	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	6	81	theme	Chemistry	835:843	arg1	Faculty					824:830	the Faculty	820:830	the Faculty of Chemistry, Hanoi Pedagogical University 2	820:875	NPK-SRFS was stocked in the Faculty of Chemistry, Hanoi Pedagogical University 2.					
35638522	1	82	dep	&lt	102:104	arg1	Objective					126:134	Objective	126:134	Objective	126:134	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	82	dep	&lt	102:104	arg1	Basil					147:151	Basil	147:151	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.)	102:192	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	82	dep	&lt	102:104	arg1	b&gt					106:109	b&gt	106:109	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.)	102:192	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	82	dep	&lt	102:104	arg1	&lt					136:138	&lt	136:138	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.)	102:192	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	82	dep	&lt	102:104	arg1	/b&gt					140:144	/b&gt	140:144	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.)	102:192	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	1	82	dep	&lt	102:104	arg1	Background					111:120	Background	111:120	Background	111:120	&lt;b&gt;Background and Objective:&lt;/b&gt; Basil (&lt;i&gt;Ocimum basilicum&lt;/i&gt; L.), an aromatic herb, is considered one of the most important crops with essential oils as well as other bioactive compounds.					
35638522	7	83	theme	block	930:934	arg1	model					936:940	a fully randomized block model	911:940	a fully randomized block model	911:940	The experiments were designed in a fully randomized block model, consisting of four treatments with different rates of NPK-SRFS.					
35638522	11	84	theme	plant	1368:1372	arg1	height					1374:1379	plant height	1368:1379	plant height	1368:1379	However, NPK-SRFS at different rates affected diversely plant height and leaf area of the basil.					
35638522	10	85	dep	&lt	1169:1171	arg1	&lt					1186:1188	&lt	1186:1188	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.	1169:1310	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	10	85	dep	&lt	1169:1171	arg1	/b&gt					1190:1194	/b&gt	1190:1194	/b&gt	1190:1194	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	10	85	dep	&lt	1169:1171	arg1	increased					1237:1245	increased	1237:1245	significantly increased the number of buds	1223:1264	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	10	85	dep	&lt	1169:1171	arg1	b&gt					1173:1176	b&gt	1173:1176	b&gt	1173:1176	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	10	85	dep	&lt	1169:1171	arg1	leaves					1270:1275	leaves	1270:1275	leaves per plant compared to the control	1270:1309	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	10	85	dep	&lt	1169:1171	arg1	Results					1178:1184	Results	1178:1184	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.	1169:1310	&lt;b&gt;Results:&lt;/b&gt; All 3 NPK-SRFS treatments significantly increased the number of buds and leaves per plant compared to the control.					
35638522	9	86	theme	Range	1106:1110	arg1	Test					1112:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test	1088:1115	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	12	87	theme	NPK-SRFS	1512:1519	arg1	treatment					1521:1529	none NPK-SRFS treatment	1507:1529	none NPK-SRFS treatment	1507:1529	F5.0 and F10 treatments accelerated chlorophyll content as well as Fv/Fm value in comparison with none NPK-SRFS treatment.					
35638522	13	88	theme	abundant	1701:1708	arg1	monoterpene					1721:1731	the most abundant oxygenated monoterpene	1692:1731	the most abundant oxygenated monoterpene	1692:1731	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	5	89	dep	&lt	690:692	arg1	/b&gt					725:729	/b&gt	725:729	/b&gt	725:729	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	89	dep	&lt	690:692	arg1	Methods					713:719	Methods	713:719	Methods	713:719	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	89	dep	&lt	690:692	arg1	seedlings					738:746	Basil seedlings	732:746	Basil seedlings	732:746	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	89	dep	&lt	690:692	arg1	&lt					721:723	&lt	721:723	&lt	721:723	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	89	dep	&lt	690:692	arg1	b&gt					694:697	b&gt	694:697	b&gt	694:697	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	5	89	dep	&lt	690:692	arg1	Materials					699:707	Materials	699:707	Materials	699:707	&lt;b&gt;Materials and Methods:&lt;/b&gt; Basil seedlings, sown from seeds, were used as plant materials.					
35638522	14	90	theme	NPK-SRFS	1899:1906	arg1	influence					1886:1894	the influence	1882:1894	the influence of NPK-SRFS on the growth, yield and essential oil components of basil	1882:1965	&lt;b&gt;Conclusion:&lt;/b&gt; The present study provides further insight into the influence of NPK-SRFS on the growth, yield and essential oil components of basil.					
35638522	4	91	theme	basil	644:648	arg1	growth					598:603	growth	598:603	growth	598:603	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	4	91	theme	basil	644:648	arg1	components					630:639	essential oil components	616:639	essential oil components	616:639	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	4	91	theme	basil	644:648	arg1	yield					606:610	yield	606:610	yield	606:610	This work aims to discover the effect of NPK Slow-Release Fertilizer Coated by Starch (NPK-SRFS) at different rates on growth, yield and essential oil components of basil grown on the field in Northern Vietnam.					
35638522	13	92	theme	Chavicol	1682:1689	arg1	α-trans-Bergamotene					1737:1755	α-trans-Bergamotene	1737:1755	α-trans-Bergamotene	1737:1755	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	92	theme	Chavicol	1682:1689	arg1	monoterpene					1721:1731	the most abundant oxygenated monoterpene	1692:1731	the most abundant oxygenated monoterpene	1692:1731	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	92	theme	Chavicol	1682:1689	arg1	changes					1605:1611	slightly different changes	1586:1611	slightly different changes in basil essential oil composition	1586:1646	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	92	theme	Chavicol	1682:1689	arg1	hydrocarbon					1790:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	the most abundant sesquiterpene hydrocarbon	1758:1800	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	13	92	theme	Chavicol	1682:1689	arg1	content					1664:1670	the content	1660:1670	the content of Methyl Chavicol	1660:1689	The application of NPK-SRFS at different rates caused slightly different changes in basil essential oil composition, especially the content of Methyl Chavicol, the most abundant oxygenated monoterpene and α-trans-Bergamotene, the most abundant sesquiterpene hydrocarbon.					
35638522	9	93	theme	statistical	1136:1146	arg1	p					1158:1158	p = 0.05	1158:1165	p = 0.05	1158:1165	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35638522	9	93	theme	statistical	1136:1146	arg1	analysis					1148:1155	statistical analysis	1136:1155	statistical analysis (p = 0.05)	1136:1166	Duncan's Multiple Range Test was being used for statistical analysis (p = 0.05).					
35690157	8	0	theme	crucial	1031:1037	arg1	effect					1039:1044	The crucial effect	1027:1044	The crucial effect of reaction conditions on PtNPs performance	1027:1088	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	6	1	theme	structural	669:678	arg1	properties					680:689	structural properties	669:689	structural properties	669:689	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	5	2	theme	agent	624:628	arg1	use					594:596	the use	590:596	the use of an additional reducing agent or ethylene glycol	590:647	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	3	3	theme	TOCN	310:313	arg1	nanocellulose					315:327	TOCN nanocellulose	310:327	TOCN nanocellulose	310:327	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	4	4	theme	PtNPs	485:489	arg1	morphology					471:480	the morphology	467:480	the morphology of PtNPs	467:489	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	5	5	theme	additional	604:613	arg1	agent					624:628	an additional reducing agent	601:628	an additional reducing agent	601:628	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	6	6	theme	diffraction	797:807	arg1	techniques					809:818	spectroscopic, microscopic and diffraction techniques	766:818	techniques	809:818	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	2	7	theme	co-reducing	271:281	arg1	nanocellulose					229:241	TEMPO-oxidized nanocellulose	214:241	TEMPO-oxidized nanocellulose (TOCN)	214:248	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	7	theme	co-reducing	271:281	arg1	agent					283:287	a stabilizing and co-reducing agent	253:287	a stabilizing and co-reducing agent	253:287	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	7	8	theme	TOCN	980:983	arg1	suspension					985:994	the TOCN suspension	976:994	the TOCN suspension applied during Pt4+ reduction	976:1024	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	4	9	theme	suspensions	452:462	arg1	pH					433:434	different pH	423:434	different pH of aqueous TOCN suspensions	423:462	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	5	10	theme	reducing	615:622	arg1	agent					624:628	an additional reducing agent	601:628	an additional reducing agent	601:628	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	6	11	from	performance	835:845	arg1	reduction					864:872	4-nitrophenol reduction	850:872	4-nitrophenol reduction	850:872	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	3	12	theme	Pt4+	332:335	arg1	ions					337:340	Pt4+ ions	332:340	Pt4+ ions	332:340	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	4	13	theme	TOCN	447:450	arg1	suspensions					452:462	aqueous TOCN suspensions	439:462	aqueous TOCN suspensions	439:462	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	8	14	theme	conditions	1058:1067	arg1	effect					1039:1044	The crucial effect	1027:1044	The crucial effect of reaction conditions on PtNPs performance	1027:1088	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	6	15	theme	microscopic	781:791	arg1	techniques					809:818	spectroscopic, microscopic and diffraction techniques	766:818	techniques	809:818	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	2	16	theme	stabilizing	255:265	arg1	nanocellulose					229:241	TEMPO-oxidized nanocellulose	214:241	TEMPO-oxidized nanocellulose (TOCN)	214:248	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	16	theme	stabilizing	255:265	arg1	agent					283:287	a stabilizing and co-reducing agent	253:287	a stabilizing and co-reducing agent	253:287	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	17	theme	platinum	131:138	arg1	PtNPs					155:159	PtNPs	155:159	PtNPs	155:159	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	17	theme	platinum	131:138	arg1	nanoparticles					140:152	platinum nanoparticles	131:152	platinum nanoparticles (PtNPs)	131:160	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	8	18	theme	reaction	1049:1056	arg1	conditions					1058:1067	reaction conditions	1049:1067	reaction conditions	1049:1067	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	0	19	theme	TEMPO-oxidized	0:13	arg1	cellulose					15:23	TEMPO-oxidized cellulose	0:23	TEMPO-oxidized cellulose for in situ synthesis of Pt	0:51	TEMPO-oxidized cellulose for in situ synthesis of Pt nanoparticles.					
35690157	8	20	theme	PtNPs	1072:1076	arg1	performance					1078:1088	PtNPs performance	1072:1088	PtNPs performance	1072:1088	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	6	21	theme	spectroscopic	766:778	arg1	techniques					809:818	spectroscopic, microscopic and diffraction techniques	766:818	techniques	809:818	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	1	22	theme	catalytic	77:85	arg1	properties					105:114	catalytic and antimicrobial properties	77:114	catalytic and antimicrobial properties	77:114	Study of catalytic and antimicrobial properties.					
35690157	5	23	dep	TOCN	577:580	arg1	the					561:563	the	561:563	the	561:563	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	5	23	dep	TOCN	577:580	arg1	presence					565:572	presence	565:572	presence	565:572	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	3	24	theme	optimum	372:378	arg1	effect					392:397	the optimum stabilizing effect	368:397	the optimum stabilizing effect of PtNPs	368:406	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	7	25	from	differences	901:911	arg1	constants					930:938	reaction rate constants k	916:940	reaction rate constants k	916:940	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	0	26	theme	in	29:30	arg1	synthesis					37:45	in situ synthesis	29:45	in situ synthesis of Pt	29:51	TEMPO-oxidized cellulose for in situ synthesis of Pt nanoparticles.					
35690157	8	27	from	effect	1039:1044	arg1	performance					1078:1088	PtNPs performance	1072:1088	PtNPs performance	1072:1088	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	6	28	dep	morphology	654:663	arg1	The					650:652	The	650:652	The	650:652	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	1	29	theme	antimicrobial	91:103	arg1	properties					105:114	catalytic and antimicrobial properties	77:114	catalytic and antimicrobial properties	77:114	Study of catalytic and antimicrobial properties.					
35690157	8	30	theme	antibacterial	1116:1128	arg1	efficacy					1130:1137	antibacterial efficacy	1116:1137	antibacterial efficacy against E. coli	1116:1153	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	4	31	theme	pH	433:434	arg1	effect					413:418	The effect	409:418	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs	409:489	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	1	32	theme	properties	105:114	arg1	Study					68:72	Study	68:72	Study of catalytic and antimicrobial properties.	68:115	Study of catalytic and antimicrobial properties.					
35690157	4	33	theme	different	423:431	arg1	pH					433:434	different pH	423:434	different pH of aqueous TOCN suspensions	423:462	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	3	34	theme	PtNPs	402:406	arg1	effect					392:397	the optimum stabilizing effect	368:397	the optimum stabilizing effect of PtNPs	368:406	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	4	35	theme	aqueous	439:445	arg1	suspensions					452:462	aqueous TOCN suspensions	439:462	aqueous TOCN suspensions	439:462	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	2	36	theme	TEMPO-oxidized	214:227	arg1	TOCN					244:247	TOCN	244:247	TOCN	244:247	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	36	theme	TEMPO-oxidized	214:227	arg1	nanocellulose					229:241	TEMPO-oxidized nanocellulose	214:241	TEMPO-oxidized nanocellulose (TOCN)	214:248	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	2	36	theme	TEMPO-oxidized	214:227	arg1	agent					283:287	a stabilizing and co-reducing agent	253:287	a stabilizing and co-reducing agent	253:287	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	0	37	theme	Pt	50:51	arg1	synthesis					37:45	in situ synthesis	29:45	in situ synthesis of Pt	29:51	TEMPO-oxidized cellulose for in situ synthesis of Pt nanoparticles.					
35690157	3	38	theme	Different	290:298	arg1	ratios					300:305	Different ratios	290:305	Different ratios of TOCN nanocellulose to Pt4+ ions	290:340	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	6	39	theme	composites	735:744	arg1	morphology					654:663	morphology	654:663	morphology	654:663	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	6	39	theme	composites	735:744	arg1	properties					680:689	structural properties	669:689	structural properties	669:689	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	7	40	dep	constants	930:938	arg1	k					940:940	k	940:940	reaction rate constants k	916:940	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	4	41	from	effect	413:418	arg1	morphology					471:480	the morphology	467:480	the morphology of PtNPs	467:489	The effect of different pH of aqueous TOCN suspensions on the morphology of PtNPs was also examined.					
35690157	2	42	theme	polyol	193:198	arg1	process					200:206	a modified polyol process	182:206	a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent	182:287	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	6	43	theme	catalytic	825:833	arg1	performance					835:845	The catalytic performance	821:845	The catalytic performance in 4-nitrophenol reduction	821:872	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	6	44	theme	nanoparticles	721:733	arg1	composites					735:744	the nanocellulose‑platinum nanoparticles composites	694:744	the nanocellulose‑platinum nanoparticles composites	694:744	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	6	45	theme	4-nitrophenol	850:862	arg1	reduction					864:872	4-nitrophenol reduction	850:872	4-nitrophenol reduction	850:872	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	7	46	theme	rate	925:928	arg1	constants					930:938	reaction rate constants k	916:940	reaction rate constants k	916:940	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	5	47	theme	ethylene	633:640	arg1	glycol					642:647	ethylene glycol	633:647	ethylene glycol	633:647	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	2	48	theme	modified	184:191	arg1	process					200:206	a modified polyol process	182:206	a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent	182:287	In this work, platinum nanoparticles (PtNPs) were synthesized by a modified polyol process using TEMPO-oxidized nanocellulose (TOCN) as a stabilizing and co-reducing agent.					
35690157	0	49	dep	in	29:30	arg1	situ					32:35	situ	32:35	situ	32:35	TEMPO-oxidized cellulose for in situ synthesis of Pt nanoparticles.					
35690157	6	50	theme	nanocellulose‑platinum	698:719	arg1	composites					735:744	the nanocellulose‑platinum nanoparticles composites	694:744	the nanocellulose‑platinum nanoparticles composites	694:744	The morphology and structural properties of the nanocellulose‑platinum nanoparticles composites were assessed using spectroscopic, microscopic and diffraction techniques, The catalytic performance in 4-nitrophenol reduction was evaluated.					
35690157	5	51	theme	glycol	642:647	arg1	use					594:596	the use	590:596	the use of an additional reducing agent or ethylene glycol	590:647	It was proved that PtNPs can be obtained solely in the presence of TOCN without the use of an additional reducing agent or ethylene glycol.					
35690157	7	52	theme	suspension	985:994	arg1	pH					970:971	the pH	966:971	the pH of the TOCN suspension applied during Pt4+ reduction	966:1024	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	3	53	theme	nanocellulose	315:327	arg1	ratios					300:305	Different ratios	290:305	Different ratios of TOCN nanocellulose to Pt4+ ions	290:340	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	7	54	theme	Pt4+	1011:1014	arg1	reduction					1016:1024	Pt4+ reduction	1011:1024	Pt4+ reduction	1011:1024	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	8	55	theme	efficacy	1130:1137	arg1	tests					1107:1111	tests	1107:1111	tests of antibacterial efficacy against E. coli	1107:1153	The crucial effect of reaction conditions on PtNPs performance was confirmed in tests of antibacterial efficacy against E. coli.					
35690157	7	56	theme	reaction	916:923	arg1	constants					930:938	reaction rate constants k	916:940	reaction rate constants k	916:940	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
35690157	3	57	theme	stabilizing	380:390	arg1	effect					392:397	the optimum stabilizing effect	368:397	the optimum stabilizing effect of PtNPs	368:406	Different ratios of TOCN nanocellulose to Pt4+ ions were studied to establish the optimum stabilizing effect of PtNPs.					
35690157	7	58	theme	Significant	889:899	arg1	differences					901:911	Significant differences	889:911	Significant differences in reaction rate constants k	889:940	Significant differences in reaction rate constants k were found depending on the pH of the TOCN suspension applied during Pt4+ reduction.					
36613889	8	0	theme	antioxidant	1084:1094	arg1	activity					1096:1103	antioxidant activity	1084:1103	antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays)	1084:1137	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	2	1	from	effects	422:428	arg1	health					439:444	human health	433:444	human health	433:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	5	2	theme	%	788:788	arg1	addition					769:776	the addition	765:776	the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	765:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	4	3	theme	study	555:559	arg1	aim					543:545	The aim	539:545	The aim of this study	539:559	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	10	4	theme	2	1284:1284	arg1	%					1285:1285	%	1285:1285	%	1285:1285	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	9	5	theme	Individual	1173:1182	arg1	polyphenols					1184:1194	Individual polyphenols	1173:1194	Individual polyphenols	1173:1194	Individual polyphenols were evaluated using HPLC-DAD analysis.					
36613889	8	6	theme	spectrophotometric	1145:1162	arg1	methods					1164:1170	spectrophotometric methods	1145:1170	spectrophotometric methods	1145:1170	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	10	7	theme	total	1322:1326	arg1	polyphenols					1328:1338	total polyphenols	1322:1338	total polyphenols	1322:1338	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	10	8	theme	CMC	1287:1289	arg1	hydrogels					1291:1299	2% CMC hydrogels	1284:1299	2% CMC hydrogels	1284:1299	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	0	9	theme	HPLC-DAD	110:117	arg1	Analysis					119:126	HPLC-DAD Analysis	110:126	HPLC-DAD Analysis	110:126	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	4	10	theme	disaccharides	597:609	arg1	addition					611:618	disaccharides addition	597:618	disaccharides addition	597:618	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	8	11	dep	activity	1096:1103	arg1	DPPH					1120:1123	DPPH	1120:1123	DPPH	1120:1123	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	8	11	dep	activity	1096:1103	arg1	assays					1131:1136	ABTS assays	1126:1136	ABTS assays	1126:1136	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	8	11	dep	activity	1096:1103	arg1	CUPRAC					1112:1117	CUPRAC	1112:1117	CUPRAC	1112:1117	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	8	11	dep	activity	1096:1103	arg1	FRAP					1106:1109	FRAP	1106:1109	FRAP	1106:1109	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	3	12	theme	food	470:473	arg1	ingredients					475:485	other natural food ingredients	456:485	other natural food ingredients	456:485	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	3	12	theme	food	470:473	arg1	disaccharides					496:508	disaccharides	496:508	disaccharides	496:508	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	3	13	theme	other	456:460	arg1	ingredients					475:485	other natural food ingredients	456:485	other natural food ingredients	456:485	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	3	13	theme	other	456:460	arg1	disaccharides					496:508	disaccharides	496:508	disaccharides	496:508	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	2	14	theme	Chokeberry	265:274	arg1	products					276:283	Chokeberry products	265:283	Chokeberry products	265:283	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	5	15	theme	disaccharides	801:813	arg1	%					788:788	40%	786:788	40%	786:788	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	15	theme	disaccharides	801:813	arg1	sucrose					816:822	sucrose	816:822	sucrose	816:822	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	15	theme	disaccharides	801:813	arg1	trehalose					827:835	trehalose	827:835	trehalose	827:835	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	15	theme	disaccharides	801:813	arg1	%					783:783	30%	781:783	30%	781:783	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	15	theme	disaccharides	801:813	arg1	%					796:796	50%	794:796	50%	794:796	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	15	theme	disaccharides	801:813	arg1	disaccharides					801:813	disaccharides	801:813	disaccharides (sucrose or trehalose)	801:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	1	16	theme	healthy	179:185	arg1	diet					187:190	a healthy diet	177:190	a healthy diet	177:190	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	4	17	theme	addition	611:618	arg1	influence					584:592	the influence	580:592	the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels	580:672	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	5	18	theme	%	783:783	arg1	addition					769:776	the addition	765:776	the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	765:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	11	19	theme	proper	1364:1369	arg1	formulation					1371:1381	proper formulation	1364:1381	proper formulation	1364:1381	These findings confirm proper formulation is important to achieve appropriate retention of polyphenols.					
36613889	1	20	theme	diet	187:190	arg1	importance					163:172	the importance	159:172	the importance of a healthy diet	159:190	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	8	21	theme	Prepared	1001:1008	arg1	samples					1010:1016	Prepared samples	1001:1016	Prepared samples	1001:1016	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	4	22	theme	chokeberry	653:662	arg1	hydrogels					664:672	chokeberry hydrogels	653:672	chokeberry hydrogels	653:672	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	2	23	theme	human	433:437	arg1	health					439:444	human health	433:444	human health	433:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	5	24	theme	%	796:796	arg1	addition					769:776	the addition	765:776	the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	765:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	11	25	theme	appropriate	1407:1417	arg1	retention					1419:1427	appropriate retention	1407:1427	appropriate retention of polyphenols	1407:1442	These findings confirm proper formulation is important to achieve appropriate retention of polyphenols.					
36613889	0	26	theme	Hydrogels	48:56	arg1	Evaluation					0:9	Evaluation	0:9	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.	0:127	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	10	27	theme	polyphenols	1328:1338	arg1	decrease					1310:1317	a decrease	1308:1317	a decrease of total polyphenols	1308:1338	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	2	28	theme	positive	413:420	arg1	effects					422:428	other positive effects	407:428	other positive effects on human health	407:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	0	29	theme	Chokeberry/Carboxymethylcellulose	14:46	arg1	Hydrogels					48:56	Chokeberry/Carboxymethylcellulose Hydrogels	14:56	Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides	14:91	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	7	30	theme	PCA	987:989	arg1	analysis					991:998	PCA analysis	987:998	PCA analysis	987:998	The method was optimized, and the fingerprints of the mass spectra have been statistically processed using PCA analysis.					
36613889	2	31	theme	other	407:411	arg1	effects					422:428	other positive effects	407:428	other positive effects on human health	407:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	5	32	theme	chokeberry	704:713	arg1	juice					715:719	chokeberry juice	704:719	chokeberry juice	704:719	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	33	dep	disaccharides	801:813	arg1	trehalose					827:835	trehalose	827:835	trehalose	827:835	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	33	dep	disaccharides	801:813	arg1	sucrose					816:822	sucrose	816:822	sucrose	816:822	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	33	dep	disaccharides	801:813	arg1	disaccharides					801:813	disaccharides	801:813	disaccharides (sucrose or trehalose)	801:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	11	34	theme	polyphenols	1432:1442	arg1	retention					1419:1427	appropriate retention	1407:1427	appropriate retention of polyphenols	1407:1442	These findings confirm proper formulation is important to achieve appropriate retention of polyphenols.					
36613889	2	35	theme	antioxidant	382:392	arg1	activity					394:401	antioxidant activity	382:401	antioxidant activity	382:401	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	8	36	theme	ABTS	1126:1129	arg1	assays					1131:1136	ABTS assays	1126:1136	ABTS assays	1126:1136	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	8	36	theme	ABTS	1126:1129	arg1	FRAP					1106:1109	FRAP	1106:1109	FRAP	1106:1109	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	0	37	with	Hydrogels	48:56	arg1	Addition					67:74	the Addition	63:74	the Addition of Disaccharides	63:91	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	4	38	from	influence	584:592	arg1	composition					638:648	the polyphenol composition	623:648	the polyphenol composition of chokeberry hydrogels	623:672	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	1	39	with	rise	259:262	arg1	awareness					146:154	the growing awareness	134:154	the growing awareness of the importance of a healthy diet	134:190	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	2	40	theme	rich	330:333	arg1	they					319:322	they	319:322	they	319:322	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	2	40	theme	rich	330:333	arg1	source					335:340	a rich source	328:340	a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health	328:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	10	41	theme	disaccharides	1267:1279	arg1	addition					1255:1262	the addition	1251:1262	the addition of disaccharides to 2% CMC hydrogels	1251:1299	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	8	42	theme	total	1037:1041	arg1	polyphenols					1043:1053	total polyphenols	1037:1053	total polyphenols	1037:1053	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	1	43	theme	growing	138:144	arg1	awareness					146:154	the growing awareness	134:154	the growing awareness of the importance of a healthy diet	134:190	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	8	44	theme	monomeric	1056:1064	arg1	anthocyanins					1066:1077	monomeric anthocyanins	1056:1077	monomeric anthocyanins	1056:1077	Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods.					
36613889	4	45	theme	hydrogels	664:672	arg1	composition					638:648	the polyphenol composition	623:648	the polyphenol composition of chokeberry hydrogels	623:672	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	3	46	theme	natural	462:468	arg1	ingredients					475:485	other natural food ingredients	456:485	other natural food ingredients	456:485	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	3	46	theme	natural	462:468	arg1	disaccharides					496:508	disaccharides	496:508	disaccharides	496:508	However, other natural food ingredients, such as disaccharides, can affect their stability.					
36613889	7	47	theme	mass	934:937	arg1	spectra					939:945	the mass spectra	930:945	the mass spectra	930:945	The method was optimized, and the fingerprints of the mass spectra have been statistically processed using PCA analysis.					
36613889	7	48	theme	spectra	939:945	arg1	fingerprints					914:925	the fingerprints	910:925	the fingerprints of the mass spectra	910:945	The method was optimized, and the fingerprints of the mass spectra have been statistically processed using PCA analysis.					
36613889	1	49	theme	importance	163:172	arg1	awareness					146:154	the growing awareness	134:154	the growing awareness of the importance of a healthy diet	134:190	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	10	50	theme	%	1285:1285	arg1	hydrogels					1291:1299	2% CMC hydrogels	1284:1299	2% CMC hydrogels	1284:1299	Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols.					
36613889	1	51	theme	novel	225:229	arg1	formulations					231:242	novel formulations	225:242	novel formulations	225:242	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	5	52	theme	carboxymethylcellulose	731:752	arg1	%					726:726	2%	725:726	2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	725:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	52	theme	carboxymethylcellulose	731:752	arg1	CMC					755:757	CMC	755:757	CMC	755:757	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	52	theme	carboxymethylcellulose	731:752	arg1	carboxymethylcellulose					731:752	carboxymethylcellulose	731:752	carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	731:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	52	theme	carboxymethylcellulose	731:752	arg1	juice					715:719	chokeberry juice	704:719	chokeberry juice	704:719	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	5	53	with	carboxymethylcellulose	731:752	arg1	addition					769:776	the addition	765:776	the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose)	765:836	Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose).					
36613889	2	54	from	activity	394:401	arg1	health					439:444	human health	433:444	human health	433:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	4	55	theme	polyphenol	627:636	arg1	composition					638:648	the polyphenol composition	623:648	the polyphenol composition of chokeberry hydrogels	623:672	The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels.					
36613889	1	56	theme	formulations	231:242	arg1	development					210:220	the development	206:220	the development of novel formulations	206:242	With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise.					
36613889	0	57	theme	Disaccharides	79:91	arg1	Addition					67:74	the Addition	63:74	the Addition of Disaccharides	63:91	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	9	58	theme	HPLC-DAD	1217:1224	arg1	analysis					1226:1233	HPLC-DAD analysis	1217:1233	HPLC-DAD analysis	1217:1233	Individual polyphenols were evaluated using HPLC-DAD analysis.					
36613889	0	59	dep	Evaluation	0:9	arg1	DART-TOF/MS					94:104	DART-TOF/MS	94:104	DART-TOF/MS	94:104	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	0	59	dep	Evaluation	0:9	arg1	Analysis					119:126	HPLC-DAD Analysis	110:126	HPLC-DAD Analysis	110:126	Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.					
36613889	2	60	theme	polyphenols	345:355	arg1	they					319:322	they	319:322	they	319:322	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
36613889	2	60	theme	polyphenols	345:355	arg1	source					335:340	a rich source	328:340	a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health	328:444	Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health.					
35989027	0	0	theme	green	101:105	arg1	catalyst					107:114	A promising green catalyst	89:114	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.	0:115	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	4	1	used	used	526:529	arg2	SEM					488:490	SEM	488:490	SEM	488:490	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	1	used	used	526:529	arg2	FTIR					503:506	FTIR	503:506	FTIR	503:506	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	1	used	used	526:529	arg2	XRD					493:495	XRD	493:495	XRD	493:495	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	1	used	used	526:529	arg2	TEM					509:511	TEM	509:511	TEM	509:511	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	1	used	used	526:529	arg2	EDX					498:500	EDX	498:500	EDX	498:500	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	1	used	used	526:529	arg2	XPS					517:519	XPS	517:519	XPS	517:519	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	0	2	theme	promising	91:99	arg1	catalyst					107:114	A promising green catalyst	89:114	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.	0:115	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	6	3	theme	kinetic	855:861	arg1	reaction					846:853	The reaction kinetic	842:861	The reaction kinetic	842:861	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	2	4	theme	water	300:304	arg1	dispersion					306:315	TEMPO-Cellulose water dispersion	284:315	TEMPO-Cellulose water dispersion in ambient conditions	284:337	The preparation implied the reduction of CoSO4 by NaBH4 in TEMPO-Cellulose water dispersion in ambient conditions.					
35989027	3	5	theme	nanoparticles	364:376	arg1	due					381:383	due	381:383	due	381:383	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	3	5	theme	nanoparticles	364:376	arg1	formation					344:352	The formation	340:352	The formation of Cobalt nanoparticles	340:376	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	2	6	theme	TEMPO-Cellulose	284:298	arg1	dispersion					306:315	TEMPO-Cellulose water dispersion	284:315	TEMPO-Cellulose water dispersion in ambient conditions	284:337	The preparation implied the reduction of CoSO4 by NaBH4 in TEMPO-Cellulose water dispersion in ambient conditions.					
35989027	4	7	theme	nanometric	619:628	arg1	size					630:633	nanometric size	619:633	nanometric size	619:633	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	0	8	theme	Co/TEMPO-cellulose	54:71	arg1	nanocomposites					73:86	Co/TEMPO-cellulose nanocomposites	54:86	Co/TEMPO-cellulose nanocomposites	54:86	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	1	9	theme	aerogel	179:185	arg1	catalyst					201:208	cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	154:208	cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	154:208	A green method for the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst was developed.					
35989027	5	10	theme	4-nitroaniline	758:771	arg1	reduction					745:753	the reduction	741:753	the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	741:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	7	11	theme	aerogel	1027:1033	arg1	catalyst					1035:1042	The aerogel catalyst	1023:1042	The aerogel catalyst	1023:1042	The aerogel catalyst was reused more than ten times without significant loss of its catalytic activity.					
35989027	1	12	theme	heterogeneous	187:199	arg1	catalyst					201:208	cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	154:208	cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	154:208	A green method for the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst was developed.					
35989027	0	13	theme	Comprehensive	0:12	arg1	preparation					14:24	Comprehensive preparation	0:24	Comprehensive preparation	0:24	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	3	14	theme	Co2+	435:438	arg1	ions					440:443	the Co2+ ions	431:443	the Co2+ ions	431:443	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	0	15	theme	catalytic	30:38	arg1	activities					40:49	catalytic activities	30:49	catalytic activities	30:49	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	0	16	dep	preparation	14:24	arg1	catalyst					107:114	A promising green catalyst	89:114	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.	0:115	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	2	17	theme	ambient	320:326	arg1	conditions					328:337	ambient conditions	320:337	ambient conditions	320:337	The preparation implied the reduction of CoSO4 by NaBH4 in TEMPO-Cellulose water dispersion in ambient conditions.					
35989027	4	18	theme	metallic	588:595	arg1	particles					604:612	metallic cobalt particles	588:612	metallic cobalt particles	588:612	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	7	19	theme	catalytic	1107:1115	arg1	activity					1117:1124	its catalytic activity	1103:1124	its catalytic activity	1103:1124	The aerogel catalyst was reused more than ten times without significant loss of its catalytic activity.					
35989027	1	20	theme	green	119:123	arg1	method					125:130	A green method	117:130	A green method for the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	117:208	A green method for the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst was developed.					
35989027	3	21	with	combination	464:474	arg1	boron					481:485	boron	481:485	boron	481:485	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	1	22	theme	catalyst	201:208	arg1	production					140:149	the production	136:149	the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst	136:208	A green method for the production of cobalt/(TEMPO-Cellulose) aerogel heterogeneous catalyst was developed.					
35989027	6	23	theme	reaction	985:992	arg1	rate					994:997	high reaction rate	980:997	high reaction rate	980:997	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	5	24	theme	4-nitrophenol	774:786	arg1	reduction					745:753	the reduction	741:753	the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	741:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	4	25	theme	cobalt	597:602	arg1	particles					604:612	metallic cobalt particles	588:612	metallic cobalt particles	588:612	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	3	26	theme	TEMPO-Cell	405:414	arg1	"					415:415	"TEMPO-Cell"	404:415	"TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron	404:485	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	3	27	theme	Cobalt	357:362	arg1	nanoparticles					364:376	Cobalt nanoparticles	357:376	Cobalt nanoparticles	357:376	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	3	28	theme	"	415:415	arg1	presence					392:399	the presence	388:399	the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron	388:485	The formation of Cobalt nanoparticles is due to the presence of "TEMPO-Cell" which screens the Co2+ ions and prevents their combination with boron.					
35989027	6	29	theme	UV-visible	878:887	arg1	spectroscopy					889:900	UV-visible spectroscopy	878:900	UV-visible spectroscopy	878:900	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	7	30	theme	significant	1083:1093	arg1	loss					1095:1098	significant loss	1083:1098	significant loss of its catalytic activity	1083:1124	The aerogel catalyst was reused more than ten times without significant loss of its catalytic activity.					
35989027	5	31	theme	model	717:721	arg1	reduction					745:753	the reduction	741:753	the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	741:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	5	31	theme	model	717:721	arg1	reactions					723:731	model reactions	717:731	model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	717:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	4	32	theme	catalyst	563:570	arg1	structure					546:554	the structure	542:554	the structure of the catalyst	542:570	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	33	contain	have	614:617	arg1	particles					604:612	metallic cobalt particles	588:612	metallic cobalt particles	588:612	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	4	33	contain	have	614:617	arg2	size					630:633	nanometric size	619:633	nanometric size	619:633	SEM, XRD, EDX, FTIR, TEM and XPS were used to analyze the structure of the catalyst and showed that metallic cobalt particles have nanometric size and are well dispersed in the aerogel.					
35989027	6	34	theme	turnover	1003:1010	arg1	frequency					1012:1020	turnover frequency	1003:1020	turnover frequency	1003:1020	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	2	35	from	dispersion	306:315	arg1	conditions					328:337	ambient conditions	320:337	ambient conditions	320:337	The preparation implied the reduction of CoSO4 by NaBH4 in TEMPO-Cellulose water dispersion in ambient conditions.					
35989027	6	36	theme	high	980:983	arg1	rate					994:997	high reaction rate	980:997	high reaction rate	980:997	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	2	37	theme	CoSO4	266:270	arg1	reduction					253:261	the reduction	249:261	the reduction of CoSO4	249:270	The preparation implied the reduction of CoSO4 by NaBH4 in TEMPO-Cellulose water dispersion in ambient conditions.					
35989027	5	38	theme	2-nitrophenol	792:804	arg1	reduction					745:753	the reduction	741:753	the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	741:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	5	39	theme	NaBH4	835:839	arg1	presence					823:830	the presence	819:830	the presence of NaBH4	819:839	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	6	40	theme	%	963:963	arg1	reduction					965:973	100 % reduction	959:973	100 % reduction	959:973	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	0	41	theme	nanocomposites	73:86	arg1	preparation					14:24	Comprehensive preparation	0:24	Comprehensive preparation	0:24	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	0	41	theme	nanocomposites	73:86	arg1	activities					40:49	catalytic activities	30:49	catalytic activities	30:49	Comprehensive preparation and catalytic activities of Co/TEMPO-cellulose nanocomposites: A promising green catalyst.					
35989027	5	42	from	reduction	745:753	arg1	water					809:813	water	809:813	water	809:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35989027	6	43	theme	100 	959:962	arg1	%					963:963	%	963:963	%	963:963	The reaction kinetic was studied by UV-visible spectroscopy, which showed that this catalyst is efficient to achieve 100 % reduction with high reaction rate and turnover frequency.					
35989027	7	44	theme	activity	1117:1124	arg1	loss					1095:1098	significant loss	1083:1098	significant loss of its catalytic activity	1083:1124	The aerogel catalyst was reused more than ten times without significant loss of its catalytic activity.					
35989027	5	45	theme	excellent	694:702	arg1	activity					704:711	excellent activity	694:711	excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water	694:813	The catalyst showed excellent activity for model reactions such as the reduction of 4-nitroaniline, 4-nitrophenol and 2-nitrophenol in water, in the presence of NaBH4.					
35190908	11	0	contain	have	1953:1956	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	11	0	contain	have	1953:1956	arg2	potential					1974:1982	osteoconductive potential	1958:1982	osteoconductive potential	1958:1982	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	1	theme	improved	266:273	arg1	survival					275:282	improved survival	266:282	improved survival	266:282	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	3	2	theme	Ti	603:604	arg1	substrates					606:615	Ti substrates	603:615	Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	603:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	8	3	theme	electrophoretic	1280:1294	arg1	deposition					1296:1305	electrophoretic deposition	1280:1305	electrophoretic deposition	1280:1305	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	10	4	theme	increased	1656:1664	arg1	production					1666:1675	increased production	1656:1675	increased production of bone-specific protein osteocalcin	1656:1712	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	5	5	theme	Scanning	941:948	arg1	SEM					971:973	SEM	971:973	SEM	971:973	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	5	5	theme	Scanning	941:948	arg1	Microscopy					959:968	Scanning Electron Microscopy	941:968	Scanning Electron Microscopy (SEM)	941:974	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	8	6	from	coating	1255:1261	arg1	samples					1269:1275	Ti samples	1266:1275	Ti samples	1266:1275	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	1	7	theme	coatings	215:222	arg1	area					196:199	the area	192:199	the area of biomimetic coatings	192:222	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	8	8	theme	AW-Chitosan	1243:1253	arg1	coating					1255:1261	The AW-Chitosan coating	1239:1261	The AW-Chitosan coating on Ti samples by electrophoretic deposition	1239:1305	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	8	9	theme	positive	1327:1334	arg1	influence					1336:1344	significant positive influence	1315:1344	significant positive influence on cell proliferation, growth and mineralization	1315:1393	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	10	10	theme	protein	1694:1700	arg1	osteocalcin					1702:1712	bone-specific protein osteocalcin	1680:1712	bone-specific protein osteocalcin	1680:1712	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	7	11	theme	Confocal	1131:1138	arg1	CSLM					1145:1148	CSLM	1145:1148	CSLM	1145:1148	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	7	11	theme	Confocal	1131:1138	arg1	LSM					1140:1142	Confocal LSM	1131:1142	Confocal LSM (CSLM) analysis	1131:1158	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	8	12	theme	cell	1349:1352	arg1	proliferation					1354:1366	cell proliferation	1349:1366	cell proliferation	1349:1366	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	7	13	theme	Red	1112:1114	arg1	staining					1118:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	3	14	theme	composite	639:647	arg1	coating					649:655	the novel composite coating	629:655	the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	629:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	5	15	theme	Scanning	986:993	arg1	LSM					1007:1009	LSM	1007:1009	LSM	1007:1009	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	5	15	theme	Scanning	986:993	arg1	Microscopy					995:1004	Laser Scanning Microscopy	980:1004	Laser Scanning Microscopy (LSM)	980:1010	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	9	16	theme	MG-63	1597:1601	arg1	cells					1603:1607	MG-63 cells	1597:1607	MG-63 cells	1597:1607	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	5	17	theme	MG-63	836:840	arg1	cells					842:846	MG-63 cells	836:846	MG-63 cells	836:846	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	3	18	theme	apatite-wollastonite	668:687	arg1	coating					649:655	the novel composite coating	629:655	the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	629:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	6	19	theme	FITC	1072:1075	arg1	tagging					1077:1083	FITC tagging	1072:1083	FITC tagging	1072:1083	Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis.					
35190908	0	20	from	function	20:27	arg1	surfaces					49:56	titanium implant surfaces	32:56	titanium implant surfaces	32:56	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	3	21	from	function	591:598	arg1	substrates					606:615	Ti substrates	603:615	Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	603:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	11	22	theme	electrophoretic	1912:1926	arg1	technique					1939:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	11	23	theme	inorganic-organic	1815:1831	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	7	24	from	mineralization	1191:1204	arg1	samples					1222:1228	the titanium samples	1209:1228	the titanium samples	1209:1228	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	8	25	theme	uncoated	1410:1417	arg1	samples					1428:1434	uncoated titanium samples	1410:1434	uncoated titanium samples	1410:1434	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	0	26	theme	experimental	118:129	arg1	study					140:144	an experimental in-vitro study	115:144	nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study	70:144	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	6	27	theme	cells	1050:1054	arg1	expression					1025:1034	Osteocalcin expression	1013:1034	Osteocalcin expression of the seeded cells	1013:1054	Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis.					
35190908	9	28	dep	microscopy	1455:1464	arg1	experiments					1496:1506	experiments	1496:1506	experiments	1496:1506	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	1	29	dep	BACKGROUND	147:156	arg1	is					164:165	is	164:165	is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	164:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	0	30	theme	implant	41:47	arg1	surfaces					49:56	titanium implant surfaces	32:56	titanium implant surfaces	32:56	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	0	31	theme	Improved	0:7	arg1	function					20:27	Improved osteoblast function	0:27	Improved osteoblast function on titanium implant surfaces	0:56	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	1	32	theme	long-term	288:296	arg1	outcomes					309:316	long-term successful outcomes	288:316	long-term successful outcomes	288:316	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	0	33	dep	Apatite-Wollastonite-Chitosan-	84:113	arg1	study					140:144	an experimental in-vitro study	115:144	nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study	70:144	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	11	34	theme	phase	1833:1837	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	35	theme	continuous	169:178	arg1	research					180:187	a continuous research	167:187	a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	167:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	3	36	theme	chitosan	706:713	arg1	coating					649:655	the novel composite coating	629:655	the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	629:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	0	37	theme	titanium	32:39	arg1	surfaces					49:56	titanium implant surfaces	32:56	titanium implant surfaces	32:56	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	10	38	theme	functional	1620:1629	arg1	activity					1631:1638	Increased functional activity	1610:1638	Increased functional activity	1610:1638	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	11	39	theme	optimal	1807:1813	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	2	40	theme	In-vitro	361:368	arg1	approaches					370:379	In-vitro approaches	361:379	In-vitro approaches	361:379	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	2	40	theme	In-vitro	361:368	arg1	systems					391:397	ideal systems	385:397	ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models	385:500	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	5	41	theme	coated	869:874	arg1	substrates					876:885	the coated substrates	865:885	the coated substrates	865:885	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	9	42	theme	electron	1446:1453	arg1	microscopy					1455:1464	Scanning electron microscopy	1437:1464	Scanning electron microscopy	1437:1464	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	11	43	contain	have	1992:1995	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	11	43	contain	have	1992:1995	arg2	application					2002:2012	wide application	1997:2012	wide application	1997:2012	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	8	44	dep	RESULTS	1231:1237	arg1	exerted					1307:1313	exerted	1307:1313	exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples	1307:1434	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	11	45	theme	wide	1997:2000	arg1	application					2002:2012	wide application	1997:2012	wide application	1997:2012	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	46	theme	Ti	241:242	arg1	surfaces					253:260	the titanium (Ti) implant surfaces	227:260	the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	227:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	3	47	dep	PURPOSE	503:509	arg1	undertaken					533:542	undertaken	533:542	was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	529:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	11	48	theme	crack-free	1853:1862	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	3	49	theme	osteoblast	560:569	arg1	characteristics					571:585	the osteoblast characteristics	556:585	the osteoblast characteristics	556:585	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	9	50	theme	confocal	1476:1483	arg1	microscopy					1485:1494	laser confocal microscopy	1470:1494	laser confocal microscopy	1470:1494	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	7	51	used	used	1164:1167	arg2	staining					1118:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	7	51	used	used	1164:1167	arg2	analysis					1151:1158	Confocal LSM (CSLM) analysis	1131:1158	Confocal LSM (CSLM) analysis	1131:1158	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	10	52	theme	bone-specific	1680:1692	arg1	osteocalcin					1702:1712	bone-specific protein osteocalcin	1680:1712	bone-specific protein osteocalcin	1680:1712	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	1	53	from	outcomes	309:316	arg1	field					325:329	the field	321:329	the field of dentistry and orthopedics	321:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	3	54	from	characteristics	571:585	arg1	substrates					606:615	Ti substrates	603:615	Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	603:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	1	55	theme	biomimetic	204:213	arg1	coatings					215:222	biomimetic coatings	204:222	biomimetic coatings	204:222	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	10	56	theme	mineralized	1718:1728	arg1	calcium					1730:1736	mineralized calcium	1718:1736	mineralized calcium through day 7 and 14	1718:1757	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	11	57	theme	present	1776:1782	arg1	study					1784:1788	The present study	1772:1788	The present study	1772:1788	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	7	58	theme	LSM	1140:1142	arg1	analysis					1151:1158	Confocal LSM (CSLM) analysis	1131:1158	Confocal LSM (CSLM) analysis	1131:1158	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	5	59	theme	Electron	950:957	arg1	SEM					971:973	SEM	971:973	SEM	971:973	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	5	59	theme	Electron	950:957	arg1	Microscopy					959:968	Scanning Electron Microscopy	941:968	Scanning Electron Microscopy (SEM)	941:974	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	6	60	theme	seeded	1043:1048	arg1	cells					1050:1054	the seeded cells	1039:1054	the seeded cells	1039:1054	Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis.					
35190908	2	61	located	observed	475:482	arg2	complexity					447:456	complexity	447:456	complexity	447:456	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	2	61	located	observed	475:482	arg1	models					495:500	in-vivo models	487:500	in-vivo models	487:500	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	10	62	theme	osteocalcin	1702:1712	arg1	production					1666:1675	increased production	1656:1675	increased production of bone-specific protein osteocalcin	1656:1712	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	10	62	theme	osteocalcin	1702:1712	arg1	calcium					1730:1736	mineralized calcium	1718:1736	mineralized calcium through day 7 and 14	1718:1757	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	11	63	theme	osteoconductive	1958:1972	arg1	potential					1974:1982	osteoconductive potential	1958:1982	osteoconductive potential	1958:1982	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	64	from	survival	275:282	arg1	field					325:329	the field	321:329	the field of dentistry and orthopedics	321:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	8	65	theme	significant	1315:1325	arg1	influence					1336:1344	significant positive influence	1315:1344	significant positive influence on cell proliferation, growth and mineralization	1315:1393	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	7	66	theme	S	1116:1116	arg1	staining					1118:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	9	67	theme	enhanced	1558:1565	arg1	cells					1551:1555	cells	1551:1555	cells	1551:1555	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	9	67	theme	enhanced	1558:1565	arg1	adhesion					1567:1574	adhesion	1567:1574	adhesion	1567:1574	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	6	68	theme	Osteocalcin	1013:1023	arg1	expression					1025:1034	Osteocalcin expression	1013:1034	Osteocalcin expression of the seeded cells	1013:1054	Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis.					
35190908	12	69	dep	abstract	2054:2061	arg1	Graphical					2044:2052	Graphical	2044:2052	Graphical	2044:2052	Graphical abstract.					
35190908	7	70	theme	Alizarin	1103:1110	arg1	staining					1118:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining	1103:1125	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	11	71	dep	simple	1889:1894	arg1	cost-effective					1897:1910	cost-effective	1897:1910	cost-effective	1897:1910	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	3	72	theme	novel	633:637	arg1	coating					649:655	the novel composite coating	629:655	the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan	629:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	5	73	theme	Laser	980:984	arg1	LSM					1007:1009	LSM	1007:1009	LSM	1007:1009	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	5	73	theme	Laser	980:984	arg1	Microscopy					995:1004	Laser Scanning Microscopy	980:1004	Laser Scanning Microscopy (LSM)	980:1010	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	8	74	theme	Ti	1266:1267	arg1	samples					1269:1275	Ti samples	1266:1275	Ti samples	1266:1275	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	4	75	theme	composite	763:771	arg1	AW-Chitosan					773:783	composite AW-Chitosan	763:783	composite AW-Chitosan	763:783	MATERIALS AND METHODS Ti substrate coated with composite AW-Chitosan was synthesized, using electrophoretic deposition.					
35190908	6	76	theme	LSM	1089:1091	arg1	analysis					1093:1100	LSM analysis	1089:1100	LSM analysis	1089:1100	Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis.					
35190908	11	77	theme	simple	1889:1894	arg1	technique					1939:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	0	78	theme	nanocomposite	70:82	arg1	Apatite-Wollastonite-Chitosan-					84:113	nanocomposite Apatite-Wollastonite-Chitosan-	70:113	nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study	70:144	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	3	79	theme	ceramic	660:666	arg1	apatite-wollastonite					668:687	ceramic apatite-wollastonite	660:687	ceramic apatite-wollastonite (AW)	660:692	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	3	79	theme	ceramic	660:666	arg1	AW					690:691	AW	690:691	AW	690:691	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	8	80	from	influence	1336:1344	arg1	mineralization					1380:1393	mineralization	1380:1393	mineralization	1380:1393	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	8	80	from	influence	1336:1344	arg1	growth					1369:1374	growth	1369:1374	growth	1369:1374	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	8	80	from	influence	1336:1344	arg1	proliferation					1354:1366	cell proliferation	1349:1366	cell proliferation	1349:1366	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	9	81	theme	cells	1603:1607	arg1	proliferation					1580:1592	proliferation	1580:1592	proliferation	1580:1592	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	9	81	theme	cells	1603:1607	arg1	cells					1551:1555	cells	1551:1555	cells	1551:1555	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	9	81	theme	cells	1603:1607	arg1	adhesion					1567:1574	adhesion	1567:1574	adhesion	1567:1574	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	4	82	theme	Ti	738:739	arg1	substrate					741:749	Ti substrate	738:749	Ti substrate	738:749	MATERIALS AND METHODS Ti substrate coated with composite AW-Chitosan was synthesized, using electrophoretic deposition.					
35190908	1	83	theme	orthopedics	348:358	arg1	field					325:329	the field	321:329	the field of dentistry and orthopedics	321:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	11	84	theme	deposition	1928:1937	arg1	technique					1939:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	simple, cost-effective electrophoretic deposition technique	1889:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	0	85	theme	in-vitro	131:138	arg1	study					140:144	an experimental in-vitro study	115:144	nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study	70:144	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	1	86	from	research	180:187	arg1	area					196:199	the area	192:199	the area of biomimetic coatings	192:222	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	1	86	from	research	180:187	arg1	surfaces					253:260	the titanium (Ti) implant surfaces	227:260	the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	227:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	8	87	theme	titanium	1419:1426	arg1	samples					1428:1434	uncoated titanium samples	1410:1434	uncoated titanium samples	1410:1434	RESULTS The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples.					
35190908	2	88	theme	cell-material	412:424	arg1	interactions					426:437	cell-material interactions	412:437	cell-material interactions	412:437	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	0	89	theme	osteoblast	9:18	arg1	function					20:27	Improved osteoblast function	0:27	Improved osteoblast function on titanium implant surfaces	0:56	Improved osteoblast function on titanium implant surfaces coated with nanocomposite Apatite-Wollastonite-Chitosan- an experimental in-vitro study.					
35190908	2	90	theme	in-vivo	487:493	arg1	models					495:500	in-vivo models	487:500	in-vivo models	487:500	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	5	91	theme	cellular	891:898	arg1	morphology					900:909	morphology	900:909	morphology	900:909	MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM).					
35190908	1	92	theme	successful	298:307	arg1	outcomes					309:316	long-term successful outcomes	288:316	long-term successful outcomes	288:316	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	3	93	theme	polymer	698:704	arg1	chitosan					706:713	polymer chitosan	698:713	polymer chitosan	698:713	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	4	94	theme	electrophoretic	808:822	arg1	deposition					824:833	electrophoretic deposition	808:833	electrophoretic deposition	808:833	MATERIALS AND METHODS Ti substrate coated with composite AW-Chitosan was synthesized, using electrophoretic deposition.					
35190908	3	95	theme	present	515:521	arg1	study					523:527	The present study	511:527	The present study	511:527	PURPOSE The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan.					
35190908	7	96	theme	in-vitro	1182:1189	arg1	mineralization					1191:1204	the in-vitro mineralization	1178:1204	the in-vitro mineralization on the titanium samples	1178:1228	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35190908	11	97	dep	CONCLUSIONS	1760:1770	arg1	underscores					1790:1800	underscores	1790:1800	underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology	1790:2041	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	98	theme	titanium	231:238	arg1	surfaces					253:260	the titanium (Ti) implant surfaces	227:260	the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	227:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	11	99	theme	implantology	2030:2041	arg1	field					2021:2025	the field	2017:2025	the field of implantology	2017:2041	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	1	100	theme	implant	245:251	arg1	surfaces					253:260	the titanium (Ti) implant surfaces	227:260	the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics	227:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	9	101	theme	Scanning	1437:1444	arg1	microscopy					1455:1464	Scanning electron microscopy	1437:1464	Scanning electron microscopy	1437:1464	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	10	102	theme	Increased	1610:1618	arg1	activity					1631:1638	Increased functional activity	1610:1638	Increased functional activity	1610:1638	Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14.					
35190908	1	103	theme	dentistry	334:342	arg1	field					325:329	the field	321:329	the field of dentistry and orthopedics	321:358	BACKGROUND There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics.					
35190908	11	104	theme	nanocomposite	1839:1851	arg1	coating					1864:1870	optimal inorganic-organic phase nanocomposite crack-free coating	1807:1870	optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique	1807:1947	CONCLUSIONS The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology.					
35190908	2	105	theme	ideal	385:389	arg1	approaches					370:379	In-vitro approaches	361:379	In-vitro approaches	361:379	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	2	105	theme	ideal	385:389	arg1	systems					391:397	ideal systems	385:397	ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models	385:500	In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models.					
35190908	9	106	theme	laser	1470:1474	arg1	microscopy					1485:1494	laser confocal microscopy	1470:1494	laser confocal microscopy	1470:1494	Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells.					
35190908	4	107	dep	MATERIALS	716:724	arg1	substrate					741:749	Ti substrate	738:749	Ti substrate	738:749	MATERIALS AND METHODS Ti substrate coated with composite AW-Chitosan was synthesized, using electrophoretic deposition.					
35190908	7	108	theme	titanium	1213:1220	arg1	samples					1222:1228	the titanium samples	1209:1228	the titanium samples	1209:1228	Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples.					
35750867	2	0	theme	present	418:424	arg1	study					426:430	The present study	414:430	The present study	414:430	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	5	1	theme	peptone	1201:1207	arg1	%					1213:1213	peptone 1.53%	1201:1213	peptone 1.53% (w v-1)	1201:1221	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	1	theme	peptone	1201:1207	arg1	v-1					1218:1220	w v-1	1216:1220	w v-1	1216:1220	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	6	2	theme	inhibition	1245:1254	arg1	effect					1256:1261	intrinsic inhibition effect	1235:1261	intrinsic inhibition effect of the substrate concentration on cellulase production	1235:1316	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	8	3	theme	cellulase	1667:1675	arg1	synthesis					1677:1685	cellulase synthesis	1667:1685	cellulase synthesis	1667:1685	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	3	4	theme	cellulose-enriched	736:753	arg1	inducer					755:761	an effective cellulose-enriched inducer	723:761	an effective cellulose-enriched inducer for the production of cellulase	723:793	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	3	5	theme	cellulase	785:793	arg1	production					771:780	the production	767:780	the production of cellulase	767:793	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	8	6	theme	0.024 IU g-1	1812:1823	arg1	h					1825:1825	0.024 IU g-1 h -1	1812:1828	0.024 IU g-1 h -1	1812:1828	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	1	7	theme	cellulases	204:213	arg1	biosynthesis					188:199	biosynthesis	188:199	biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling	188:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	4	8	theme	enhanced	958:965	arg1	production					977:986	enhanced cellulase production	958:986	enhanced cellulase production with maximum activity levels	958:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	6	9	theme	modified	1319:1326	arg1	experiments					1360:1370	modified Luedeking-Piret model simulated experiments	1319:1370	modified Luedeking-Piret model simulated experiments	1319:1370	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	1	10	theme	inexpensive	220:230	arg1	feedstock					248:256	inexpensive lignocellulosic feedstock	220:256	inexpensive lignocellulosic feedstock through appropriate kinetic modelling	220:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	7	11	theme	cellulase	1593:1601	arg1	enzyme					1603:1608	cellulase enzyme	1593:1608	cellulase enzyme on its activity during production	1593:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	5	12	with	production	1036:1045	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	8	13	theme	higher	1833:1838	arg1	concentration					1844:1856	higher NPW concentration	1833:1856	higher NPW concentration of 4% (w v-1)	1833:1870	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	3	14	theme	%	647:647	arg1	treatment					662:670	2% (w v-1) NaOH treatment	646:670	2% (w v-1) NaOH treatment	646:670	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	8	15	theme	0.040 IU g-1	1720:1731	arg1	h					1733:1733	0.040 IU g-1 h -1	1720:1736	0.040 IU g-1 h -1	1720:1736	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	7	16	theme	characteristic	1575:1588	arg1	trends					1508:1513	the trends	1504:1513	the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production	1504:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	4	17	theme	response	925:932	arg1	methodology					942:952	response surface methodology	925:952	response surface methodology for enhanced cellulase production with maximum activity levels	925:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	8	18	theme	%	1862:1862	arg1	concentration					1844:1856	higher NPW concentration	1833:1856	higher NPW concentration of 4% (w v-1)	1833:1870	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	5	19	theme	activity	1086:1093	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	6	20	theme	substrate	1270:1278	arg1	concentration					1280:1292	the substrate concentration	1266:1292	the substrate concentration	1266:1292	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	7	21	theme	substrate	1538:1546	arg1	consumption					1548:1558	substrate consumption	1538:1558	substrate consumption	1538:1558	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	1	22	theme	production	394:403	arg1	understanding					308:320	understanding	308:320	understanding	308:320	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	1	22	theme	production	394:403	arg1	optimization					323:334	optimization	323:334	optimization	323:334	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	3	23	theme	w	650:650	arg1	v-1					652:654	w v-1	650:654	w v-1	650:654	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	7	24	theme	production	1526:1535	arg1	trends					1508:1513	the trends	1504:1513	the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production	1504:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	0	25	theme	cellulase	80:88	arg1	enzyme					90:95	cellulase enzyme	80:95	cellulase enzyme	80:95	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	1	26	theme	potential	170:178	arg1	evaluation					140:149	A systematic evaluation	127:149	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling	127:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	4	27	theme	maximum	993:999	arg1	levels					1010:1015	maximum activity levels	993:1015	maximum activity levels	993:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	5	28	theme	Maximum	1018:1024	arg1	production					1036:1045	Maximum cellulase production	1018:1045	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels	1018:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	4	29	with	production	977:986	arg1	levels					1010:1015	maximum activity levels	993:1015	maximum activity levels	993:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	2	30	theme	fungal	461:466	arg1	strategy					480:487	a submerged fungal cultivation strategy	449:487	a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW)	449:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	6	31	theme	model	1344:1348	arg1	experiments					1360:1370	modified Luedeking-Piret model simulated experiments	1319:1370	modified Luedeking-Piret model simulated experiments	1319:1370	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	8	32	theme	concentration	1762:1774	arg1	concentration					1762:1774	NPW concentration	1758:1774	NPW concentration	1758:1774	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	8	32	theme	concentration	1762:1774	arg1	%					1745:1745	3.29%	1741:1745	3.29% (w v-1) of NPW concentration	1741:1774	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	8	32	theme	concentration	1762:1774	arg1	v-1					1750:1752	w v-1	1748:1752	w v-1	1748:1752	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	2	33	theme	available	530:538	arg1	wastes					550:555	abundantly available newspaper wastes	519:555	abundantly available newspaper wastes (NPW)	519:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	2	33	theme	available	530:538	arg1	NPW					558:560	NPW	558:560	NPW	558:560	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	0	34	theme	Kinetic	0:6	arg1	model					8:12	Kinetic model	0:12	Kinetic model	0:12	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	2	35	theme	cellulase	493:501	arg1	production					503:512	cellulase production	493:512	cellulase production from abundantly available newspaper wastes (NPW)	493:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	6	36	dep	%	1403:1403	arg1	concentrations					1441:1454	NPW concentrations	1437:1454	NPW concentrations	1437:1454	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	3	37	dep	diluted	608:614	arg1	%					618:618	1%	617:618	1% (v v-1)	617:626	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	3	37	dep	diluted	608:614	arg1	v-1					623:625	v v-1	621:625	v v-1	621:625	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	4	38	theme	nutrient	849:856	arg1	components					858:867	the most influential nutrient components	828:867	the most influential nutrient components like peptone and lactose	828:892	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	4	39	dep	the	913:915	arg1	help					917:920	help	917:920	help	917:920	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	1	40	theme	effective	356:364	arg1	production					394:403	an effective industrial cellulase enzyme production	353:403	an effective industrial cellulase enzyme production process	353:411	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	7	41	theme	developed	1461:1469	arg1	model					1479:1483	The developed kinetic model	1457:1483	The developed kinetic model	1457:1483	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	5	42	theme	FPU	1071:1073	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	0	43	theme	submerged	47:55	arg1	strategy					68:75	submerged production strategy	47:75	submerged production strategy of cellulase enzyme	47:95	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	1	44	theme	cellulase	377:385	arg1	production					394:403	an effective industrial cellulase enzyme production	353:403	an effective industrial cellulase enzyme production process	353:411	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	5	45	theme	total	1080:1084	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	46	theme	newspaper	704:712	arg1	waste					714:718	newspaper waste	704:718	newspaper waste	704:718	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	6	47	from	effect	1256:1261	arg1	production					1307:1316	cellulase production	1297:1316	cellulase production	1297:1316	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	5	48	theme	8.64 g	1050:1055	arg1	L-1					1057:1059	8.64 g L-1	1050:1059	8.64 g L-1	1050:1059	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	2	49	theme	cultivation	468:478	arg1	strategy					480:487	a submerged fungal cultivation strategy	449:487	a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW)	449:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	1	50	theme	kinetic	278:284	arg1	modelling					286:294	appropriate kinetic modelling	266:294	appropriate kinetic modelling	266:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	5	51	theme	lactose	1175:1181	arg1	%					1187:1187	lactose 2.94%	1175:1187	lactose 2.94% (w v-1)	1175:1195	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	51	theme	lactose	1175:1181	arg1	v-1					1192:1194	w v-1	1190:1194	w v-1	1190:1194	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	52	theme	effective	726:734	arg1	inducer					755:761	an effective cellulose-enriched inducer	723:761	an effective cellulose-enriched inducer for the production of cellulase	723:793	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	3	53	theme	pretreatment	575:586	arg1	strategy					588:595	A combined pretreatment strategy	564:595	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment	564:670	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	3	53	theme	pretreatment	575:586	arg1	effective					683:691	effective	683:691	effective	683:691	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	8	54	theme	rate	1649:1652	arg1	constant					1654:1661	The rate constant	1645:1661	The rate constant for cellulase synthesis	1645:1685	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	6	55	theme	intrinsic	1235:1243	arg1	effect					1256:1261	intrinsic inhibition effect	1235:1261	intrinsic inhibition effect of the substrate concentration on cellulase production	1235:1316	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	7	56	theme	enzyme	1603:1608	arg1	characteristic					1575:1588	characteristic	1575:1588	characteristic	1575:1588	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	6	57	theme	Luedeking-Piret	1328:1342	arg1	experiments					1360:1370	modified Luedeking-Piret model simulated experiments	1319:1370	modified Luedeking-Piret model simulated experiments	1319:1370	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	8	58	theme	NPW	1840:1842	arg1	concentration					1844:1856	higher NPW concentration	1833:1856	higher NPW concentration of 4% (w v-1)	1833:1870	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	5	59	theme	optimized	1120:1128	arg1	composition					1130:1140	optimized composition	1120:1140	optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1)	1120:1221	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	60	theme	2	646:646	arg1	%					647:647	%	647:647	%	647:647	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	6	61	theme	NPW	1437:1439	arg1	concentrations					1441:1454	NPW concentrations	1437:1454	NPW concentrations	1437:1454	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	1	62	theme	lignocellulosic	232:246	arg1	feedstock					248:256	inexpensive lignocellulosic feedstock	220:256	inexpensive lignocellulosic feedstock through appropriate kinetic modelling	220:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	7	63	theme	adsorption	1564:1573	arg1	trends					1508:1513	the trends	1504:1513	the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production	1504:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	4	64	theme	cellulase	967:975	arg1	production					977:986	enhanced cellulase production	958:986	enhanced cellulase production with maximum activity levels	958:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	6	65	theme	cellulase	1297:1305	arg1	production					1307:1316	cellulase production	1297:1316	cellulase production	1297:1316	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	1	66	from	feedstock	248:256	arg1	biosynthesis					188:199	biosynthesis	188:199	biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling	188:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	7	67	theme	consumption	1548:1558	arg1	trends					1508:1513	the trends	1504:1513	the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production	1504:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	6	68	theme	concentration	1280:1292	arg1	effect					1256:1261	intrinsic inhibition effect	1235:1261	intrinsic inhibition effect of the substrate concentration on cellulase production	1235:1316	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	1	69	theme	systematic	129:138	arg1	evaluation					140:149	A systematic evaluation	127:149	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling	127:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	4	70	theme	surface	934:940	arg1	methodology					942:952	response surface methodology	925:952	response surface methodology for enhanced cellulase production with maximum activity levels	925:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	8	71	theme	w	1865:1865	arg1	v-1					1867:1869	w v-1	1865:1869	w v-1	1865:1869	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	8	71	theme	w	1865:1865	arg1	%					1862:1862	4%	1861:1862	4% (w v-1)	1861:1870	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	7	72	theme	biomass	1518:1524	arg1	production					1526:1535	biomass production	1518:1535	biomass production	1518:1535	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	0	73	theme	enzyme	90:95	arg1	strategy					68:75	submerged production strategy	47:75	submerged production strategy of cellulase enzyme	47:95	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	5	74	theme	w	1167:1167	arg1	%					1164:1164	NPW 3.29%	1156:1164	NPW 3.29% (w v-1)	1156:1172	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	74	theme	w	1167:1167	arg1	v-1					1169:1171	w v-1	1167:1171	w v-1	1167:1171	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	75	dep	%	647:647	arg1	v-1					652:654	w v-1	650:654	w v-1	650:654	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	0	76	theme	newspaper	102:110	arg1	biomass					118:124	newspaper waste biomass	102:124	newspaper waste biomass	102:124	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	0	77	dep	supported	14:22	arg1	optimized					37:45	optimized	37:45	optimized submerged production strategy of cellulase enzyme from newspaper waste biomass	37:124	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	0	77	dep	supported	14:22	arg1	improved					24:31	improved	24:31	improved	24:31	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	8	78	theme	w	1748:1748	arg1	concentration					1762:1774	NPW concentration	1758:1774	NPW concentration	1758:1774	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	8	78	theme	w	1748:1748	arg1	%					1745:1745	3.29%	1741:1745	3.29% (w v-1) of NPW concentration	1741:1774	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	8	78	theme	w	1748:1748	arg1	v-1					1750:1752	w v-1	1748:1752	w v-1	1748:1752	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	2	79	from	wastes	550:555	arg1	production					503:512	cellulase production	493:512	cellulase production from abundantly available newspaper wastes (NPW)	493:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	6	80	theme	simulated	1350:1358	arg1	experiments					1360:1370	modified Luedeking-Piret model simulated experiments	1319:1370	modified Luedeking-Piret model simulated experiments	1319:1370	To analyse intrinsic inhibition effect of the substrate concentration on cellulase production, modified Luedeking-Piret model simulated experiments were further conducted with 1.5% (w/v), 3.29% (w/v) and 4% (w/v) NPW concentrations.					
35750867	5	81	theme	NPW	1156:1158	arg1	%					1164:1164	NPW 3.29%	1156:1164	NPW 3.29% (w v-1)	1156:1172	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	81	theme	NPW	1156:1158	arg1	v-1					1169:1171	w v-1	1167:1171	w v-1	1167:1171	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	82	theme	cellulase	1026:1034	arg1	production					1036:1045	Maximum cellulase production	1018:1045	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels	1018:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	4	83	theme	activity	1001:1008	arg1	levels					1010:1015	maximum activity levels	993:1015	maximum activity levels	993:1015	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	1	84	theme	appropriate	266:276	arg1	modelling					286:294	appropriate kinetic modelling	266:294	appropriate kinetic modelling	266:294	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	2	85	theme	submerged	451:459	arg1	strategy					480:487	a submerged fungal cultivation strategy	449:487	a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW)	449:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	7	86	from	enzyme	1603:1608	arg1	activity					1617:1624	its activity	1613:1624	its activity during production	1613:1642	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	8	87	theme	NPW	1758:1760	arg1	concentration					1762:1774	NPW concentration	1758:1774	NPW concentration	1758:1774	The rate constant for cellulase synthesis was evaluated to be increased to 0.040 IU g-1 h -1 at 3.29% (w v-1) of NPW concentration; however, it was further reduced to 0.024 IU g-1 h -1 at higher NPW concentration of 4% (w v-1).					
35750867	5	88	theme	w	1190:1190	arg1	%					1187:1187	lactose 2.94%	1175:1187	lactose 2.94% (w v-1)	1175:1195	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	88	theme	w	1190:1190	arg1	v-1					1192:1194	w v-1	1190:1194	w v-1	1190:1194	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	1	89	dep	production	394:403	arg1	process					405:411	process	405:411	an effective industrial cellulase enzyme production process	353:411	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	5	90	theme	7.82	1066:1069	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	91	theme	NaOH	657:660	arg1	treatment					662:670	2% (w v-1) NaOH treatment	646:670	2% (w v-1) NaOH treatment	646:670	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	4	92	theme	influential	837:847	arg1	components					858:867	the most influential nutrient components	828:867	the most influential nutrient components like peptone and lactose	828:892	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	0	93	theme	waste	112:116	arg1	biomass					118:124	newspaper waste biomass	102:124	newspaper waste biomass	102:124	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	0	94	theme	production	57:66	arg1	strategy					68:75	submerged production strategy	47:75	submerged production strategy of cellulase enzyme	47:95	Kinetic model supported improved and optimized submerged production strategy of cellulase enzyme from newspaper waste biomass.					
35750867	1	95	theme	industrial	366:375	arg1	production					394:403	an effective industrial cellulase enzyme production	353:403	an effective industrial cellulase enzyme production process	353:411	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	7	96	theme	kinetic	1471:1477	arg1	model					1479:1483	The developed kinetic model	1457:1483	The developed kinetic model	1457:1483	The developed kinetic model perfectly captured the trends of biomass production, substrate consumption and adsorption characteristic of cellulase enzyme on its activity during production.					
35750867	5	97	theme	mL-1	1075:1078	arg1	levels					1095:1100	7.82 FPU mL-1 total activity levels	1066:1100	7.82 FPU mL-1 total activity levels	1066:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	2	98	theme	newspaper	540:548	arg1	wastes					550:555	abundantly available newspaper wastes	519:555	abundantly available newspaper wastes (NPW)	519:561	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	2	98	theme	newspaper	540:548	arg1	NPW					558:560	NPW	558:560	NPW	558:560	The present study aims to optimize a submerged fungal cultivation strategy for cellulase production from abundantly available newspaper wastes (NPW).					
35750867	4	99	theme	components	858:867	arg1	composition					813:823	the composition	809:823	the composition of the most influential nutrient components like peptone and lactose	809:892	In addition, the composition of the most influential nutrient components like peptone and lactose was optimized with the help of response surface methodology for enhanced cellulase production with maximum activity levels.					
35750867	3	100	theme	combined	566:573	arg1	strategy					588:595	A combined pretreatment strategy	564:595	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment	564:670	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	3	100	theme	combined	566:573	arg1	effective					683:691	effective	683:691	effective	683:691	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
35750867	1	101	theme	enzyme	387:392	arg1	production					394:403	an effective industrial cellulase enzyme production	353:403	an effective industrial cellulase enzyme production process	353:411	A systematic evaluation of microorganism's potential towards biosynthesis of cellulases from inexpensive lignocellulosic feedstock through appropriate kinetic modelling facilitates understanding, optimization and designing of an effective industrial cellulase enzyme production process.					
35750867	5	102	theme	w	1216:1216	arg1	%					1213:1213	peptone 1.53%	1201:1213	peptone 1.53% (w v-1)	1201:1221	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	102	theme	w	1216:1216	arg1	v-1					1218:1220	w v-1	1216:1220	w v-1	1216:1220	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	5	103	theme	L-1	1057:1059	arg1	production					1036:1045	Maximum cellulase production	1018:1045	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels	1018:1100	Maximum cellulase production of 8.64 g L-1 with 7.82 FPU mL-1 total activity levels was achieved from optimized composition of pretreated NPW 3.29% (w v-1), lactose 2.94% (w v-1) and peptone 1.53% (w v-1).					
35750867	3	104	theme	diluted	608:614	arg1	H2SO4					628:632	diluted, 1% (v v-1) H2SO4	608:632	diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment	608:670	A combined pretreatment strategy consisting diluted, 1% (v v-1) H2SO4 followed by 2% (w v-1) NaOH treatment was highly effective to convert newspaper waste to an effective cellulose-enriched inducer for the production of cellulase.					
36551237	3	0	theme	crystals	538:545	arg1	growth					524:529	the growth	520:529	the growth of ice crystals	520:545	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	6	1	theme	Young	1019:1023	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	1	theme	Young	1019:1023	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	0	2	theme	Arcade-like	93:103	arg1	Structure					105:113	Cartilage Arcade-like Structure	83:113	Cartilage Arcade-like Structure	83:113	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	7	3	theme	available	1135:1143	arg1	methods					1127:1133	the fabrication methods	1111:1133	the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity	1111:1235	The technique presented expands the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity.					
36551237	5	4	theme	mechanical	891:900	arg1	properties					902:911	the mechanical properties	887:911	the mechanical properties of the otherwise weak collagen scaffolds	887:952	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	1	5	theme	structural	192:201	arg1	functions					218:226	their structural and biological functions	186:226	their structural and biological functions	186:226	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	2	6	theme	extracellular	318:330	arg1	macromolecules					345:358	derivatized extracellular matrix (ECM) macromolecules	306:358	derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	306:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	5	7	theme	double	758:763	arg1	networks					765:772	double networks	758:772	double networks (DNs)	758:778	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	7	theme	double	758:763	arg1	DNs					775:777	DNs	775:777	DNs	775:777	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	6	8	theme	MeHA-CollGTA	1001:1012	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	8	theme	MeHA-CollGTA	1001:1012	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	2	9	theme	derivatized	306:316	arg1	macromolecules					345:358	derivatized extracellular matrix (ECM) macromolecules	306:358	derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	306:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	4	10	theme	organized	637:645	arg1	growth					647:652	the organized growth	633:652	the organized growth of ice crystals	633:668	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	5	11	theme	hyaluronic	783:792	arg1	acid					794:797	hyaluronic acid	783:797	hyaluronic acid	783:797	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	3	12	theme	arcade-like	478:488	arg1	structure					490:498	this arcade-like structure	473:498	this arcade-like structure	473:498	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	5	13	theme	derivatives	812:822	arg1	networks					765:772	double networks	758:772	double networks (DNs)	758:778	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	13	theme	derivatives	812:822	arg1	DNs					775:777	DNs	775:777	DNs	775:777	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	14	dep	derivatives	812:822	arg1	MeHA					825:828	MeHA	825:828	MeHA	825:828	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	14	dep	derivatives	812:822	arg1	derivatives					812:822	collagen derivatives	803:822	collagen derivatives (MeHA and CollGTA, respectively)	803:855	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	14	dep	derivatives	812:822	arg1	CollGTA					834:840	CollGTA	834:840	CollGTA	834:840	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	3	15	theme	cryogenic	567:575	arg1	temperatures					577:588	cryogenic temperatures	567:588	cryogenic temperatures	567:588	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	6	16	theme	biomimetic	971:980	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	16	theme	biomimetic	971:980	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	1	17	theme	biological	207:216	arg1	functions					218:226	their structural and biological functions	186:226	their structural and biological functions	186:226	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	7	18	theme	cartilage	1216:1224	arg1	complexity					1226:1235	cartilage complexity	1216:1235	cartilage complexity	1216:1235	The technique presented expands the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity.					
36551237	4	19	theme	cryogel	607:613	arg1	formation					615:623	The directional cryogel formation	591:623	The directional cryogel formation	591:623	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	6	20	theme	resilient	991:999	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	20	theme	resilient	991:999	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	5	21	theme	collagen	935:942	arg1	scaffolds					944:952	the otherwise weak collagen scaffolds	916:952	the otherwise weak collagen scaffolds	916:952	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	2	22	theme	zonal	420:424	arg1	architecture					426:437	the typical Benninghoff zonal architecture	396:437	the typical Benninghoff zonal architecture of articular cartilage	396:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	4	23	theme	directional	595:605	arg1	formation					615:623	The directional cryogel formation	591:623	The directional cryogel formation	591:623	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	2	24	theme	ECM	340:342	arg1	macromolecules					345:358	derivatized extracellular matrix (ECM) macromolecules	306:358	derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	306:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	2	25	theme	Benninghoff	408:418	arg1	architecture					426:437	the typical Benninghoff zonal architecture	396:437	the typical Benninghoff zonal architecture of articular cartilage	396:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	0	26	theme	Acid	35:38	arg1	Cryogels					40:47	Collagen-Hyaluronic Acid Cryogels	15:47	Collagen-Hyaluronic Acid Cryogels	15:47	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	1	27	theme	internal	120:127	arg1	fundamental					171:181	fundamental	171:181	fundamental	171:181	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	1	27	theme	internal	120:127	arg1	architecture					129:140	The internal architecture	116:140	The internal architecture of tissue-like constructs	116:166	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	4	28	theme	large	677:681	arg1	distance					683:690	a large distance	675:690	a large distance (&gt;4 mm)	675:701	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	4	28	theme	large	677:681	arg1	mm					699:700	&gt;4 mm	693:700	&gt;4 mm	693:700	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	0	29	theme	Collagen-Hyaluronic	15:33	arg1	Cryogels					40:47	Collagen-Hyaluronic Acid Cryogels	15:47	Collagen-Hyaluronic Acid Cryogels	15:47	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	5	30	theme	scaffolds	944:952	arg1	properties					902:911	the mechanical properties	887:911	the mechanical properties of the otherwise weak collagen scaffolds	887:952	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	2	31	theme	matrix	332:337	arg1	macromolecules					345:358	derivatized extracellular matrix (ECM) macromolecules	306:358	derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	306:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	3	32	theme	copper	552:557	arg1	pins					559:562	copper pins	552:562	copper pins	552:562	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	5	33	theme	acid	794:797	arg1	networks					765:772	double networks	758:772	double networks (DNs)	758:778	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	33	theme	acid	794:797	arg1	DNs					775:777	DNs	775:777	DNs	775:777	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	3	34	theme	ice	534:536	arg1	crystals					538:545	ice crystals	534:545	ice crystals	534:545	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	2	35	with	macromolecules	345:358	arg1	porosity					365:372	porosity	365:372	porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	365:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	2	36	theme	robust	261:266	arg1	method					268:273	a simple and robust method	248:273	a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	248:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	2	37	theme	cartilage	452:460	arg1	architecture					426:437	the typical Benninghoff zonal architecture	396:437	the typical Benninghoff zonal architecture of articular cartilage	396:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	0	38	theme	Cryogels	40:47	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing	0:71	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	7	39	theme	architectural	1183:1195	arg1	elements					1197:1204	architectural elements	1183:1204	architectural elements mimicking cartilage complexity	1183:1235	The technique presented expands the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity.					
36551237	2	40	theme	articular	442:450	arg1	cartilage					452:460	articular cartilage	442:460	articular cartilage	442:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	5	41	theme	collagen	803:810	arg1	MeHA					825:828	MeHA	825:828	MeHA	825:828	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	41	theme	collagen	803:810	arg1	derivatives					812:822	collagen derivatives	803:822	collagen derivatives (MeHA and CollGTA, respectively)	803:855	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	41	theme	collagen	803:810	arg1	CollGTA					834:840	CollGTA	834:840	CollGTA	834:840	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	2	42	theme	simple	250:255	arg1	method					268:273	a simple and robust method	248:273	a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage	248:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	0	43	theme	Directional	52:62	arg1	Freezing					64:71	Directional Freezing	52:71	Directional Freezing	52:71	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	7	44	theme	fabrication	1115:1125	arg1	methods					1127:1133	the fabrication methods	1111:1133	the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity	1111:1235	The technique presented expands the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity.					
36551237	1	45	theme	tissue-like	145:155	arg1	constructs					157:166	tissue-like constructs	145:166	tissue-like constructs	145:166	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	1	46	theme	constructs	157:166	arg1	fundamental					171:181	fundamental	171:181	fundamental	171:181	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	1	46	theme	constructs	157:166	arg1	architecture					129:140	The internal architecture	116:140	The internal architecture of tissue-like constructs	116:166	The internal architecture of tissue-like constructs is fundamental to their structural and biological functions.					
36551237	3	47	used	used	515:518	arg2	technique					505:513	the technique	501:513	the technique	501:513	To obtain this arcade-like structure, the technique used the growth of ice crystals from copper pins at cryogenic temperatures.					
36551237	4	48	theme	ice	657:659	arg1	crystals					661:668	ice crystals	657:668	ice crystals	657:668	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	5	49	theme	compositional	708:720	arg1	properties					722:731	The compositional properties	704:731	The compositional properties	704:731	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	5	50	theme	weak	930:933	arg1	scaffolds					944:952	the otherwise weak collagen scaffolds	916:952	the otherwise weak collagen scaffolds	916:952	The compositional properties were achieved by forming double networks (DNs) of hyaluronic acid and collagen derivatives (MeHA and CollGTA, respectively), which also served to improve the mechanical properties of the otherwise weak collagen scaffolds.					
36551237	6	51	theme	≈	1035:1035	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	51	theme	≈	1035:1035	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	0	52	theme	Cartilage	83:91	arg1	Structure					105:113	Cartilage Arcade-like Structure	83:113	Cartilage Arcade-like Structure	83:113	Fabrication of Collagen-Hyaluronic Acid Cryogels by Directional Freezing Mimicking Cartilage Arcade-like Structure.					
36551237	2	53	theme	typical	400:406	arg1	architecture					426:437	the typical Benninghoff zonal architecture	396:437	the typical Benninghoff zonal architecture of articular cartilage	396:460	Here, we introduce a simple and robust method to fabricate cryogels based on derivatized extracellular matrix (ECM) macromolecules with porosity arranged according to the typical Benninghoff zonal architecture of articular cartilage.					
36551237	4	54	theme	&gt	693:695	arg1	distance					683:690	a large distance	675:690	a large distance (&gt;4 mm)	675:701	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	4	54	theme	&gt	693:695	arg1	mm					699:700	&gt;4 mm	693:700	&gt;4 mm	693:700	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36551237	6	55	theme	modulus	1027:1033	arg1	kilopascals					1041:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Young's modulus ≈ 200 kilopascals	1019:1051	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	6	55	theme	modulus	1027:1033	arg1	DNs					1014:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs	955:1016	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals)	955:1052	Compositionally biomimetic and more resilient MeHA-CollGTA DNs (Young's modulus ≈ 200 kilopascals) were therefore produced.					
36551237	7	56	theme	ECM	1159:1161	arg1	macromolecules					1163:1176	ECM macromolecules	1159:1176	ECM macromolecules	1159:1176	The technique presented expands the fabrication methods available for providing ECM macromolecules with architectural elements mimicking cartilage complexity.					
36551237	4	57	theme	crystals	661:668	arg1	growth					647:652	the organized growth	633:652	the organized growth of ice crystals	633:668	The directional cryogel formation enabled the organized growth of ice crystals over a large distance (&gt;4 mm).					
36076460	3	0	theme	corresponding	672:684	arg1	pectin					695:700	the corresponding aminated pectin	668:700	the corresponding aminated pectin	668:700	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	9	1	theme	pectin	1483:1488	arg1	application					1459:1469	the application	1455:1469	the application of amidated pectin in low-fat food	1455:1504	The results provide references for the application of amidated pectin in low-fat food.					
36076460	8	2	contain	had	1335:1337	arg2	stability					1354:1362	better colloid stability	1339:1362	better colloid stability	1339:1362	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	8	2	contain	had	1335:1337	arg1	α-AP					1330:1333	α-AP	1330:1333	α-AP	1330:1333	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	8	2	contain	had	1335:1337	arg2	particles					1385:1393	smaller hydrogel particles	1368:1393	smaller hydrogel particles in the composite system	1368:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	0	3	dep	fat	123:125	arg1	substitutes					127:137	substitutes	127:137	substitutes	127:137	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	0	4	from	fat	123:125	arg1	potential					110:118	potential	110:118	potential	110:118	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	8	5	theme	High	1294:1297	arg1	pectin					1307:1312	High methoxy pectin	1294:1312	High methoxy pectin (HMP)	1294:1318	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	8	5	theme	High	1294:1297	arg1	HMP					1315:1317	HMP	1315:1317	HMP	1315:1317	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	0	6	theme	hydrogel	70:77	arg1	properties					79:88	hydrogel properties	70:88	hydrogel properties	70:88	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	8	7	theme	better	1339:1344	arg1	stability					1354:1362	better colloid stability	1339:1362	better colloid stability	1339:1362	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	3	8	theme	resonance	487:495	arg1	analysis					497:504	proton nuclear magnetic resonance analysis	463:504	proton nuclear magnetic resonance analysis	463:504	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	5	9	theme	side	917:920	arg1	chain					922:926	amino acid side chain	906:926	amino acid side chain	906:926	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	6	10	theme	hydrogel	1004:1011	arg1	higher					1034:1039	higher	1034:1039	higher	1034:1039	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	6	10	theme	hydrogel	1004:1011	arg1	strength					992:999	the strength	988:999	the strength of hydrogel prepared by α-AP	988:1028	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	6	11	theme	elastic	1088:1094	arg1	modulus					1096:1102	elastic modulus	1088:1102	elastic modulus	1088:1102	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	8	12	from	particles	1385:1393	arg1	system					1412:1417	the composite system	1398:1417	the composite system	1398:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	6	13	theme	swelling	1108:1115	arg1	capacity					1117:1124	swelling capacity	1108:1124	swelling capacity	1108:1124	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	8	14	theme	composite	1402:1410	arg1	system					1412:1417	the composite system	1398:1417	the composite system	1398:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	4	15	theme	α-AP	733:736	arg1	ratio					724:728	The alanine grafting ratio	703:728	The alanine grafting ratio of α-AP and β-AP	703:745	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	4	15	theme	α-AP	733:736	arg1	%					757:757	21.99%	752:757	21.99%	752:757	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	2	16	from	effects	313:319	arg1	degree					364:369	amidation degree	354:369	amidation degree	354:369	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	2	16	from	effects	313:319	arg1	properties					391:400	physicochemical properties	375:400	physicochemical properties	375:400	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	2	17	theme	alanine	324:330	arg1	effects					313:319	The effects	309:319	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin	309:410	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	3	18	from	α-C	596:598	arg1	groups					584:589	the amino groups	574:589	the amino groups from α-C and β-C	574:606	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	18	from	α-C	596:598	arg1	aminated					617:624	aminated	617:624	aminated	617:624	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	0	19	theme	potential	110:118	arg1	application					98:108	its application	94:108	its application potential in fat substitutes	94:137	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	8	20	theme	colloid	1346:1352	arg1	stability					1354:1362	better colloid stability	1339:1362	better colloid stability	1339:1362	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	7	21	theme	smooth	1246:1251	arg1	taste					1266:1270	the smooth and delicate taste	1242:1270	the smooth and delicate taste of fat	1242:1277	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	3	22	theme	X-ray	507:511	arg1	spectrum					527:534	X-ray photoelectron spectrum	507:534	X-ray photoelectron spectrum	507:534	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	7	23	used	used	1204:1207	arg2	fat					1172:1174	a carbohydrate-based fat substitute	1151:1185	a carbohydrate-based fat substitute	1151:1185	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	7	23	used	used	1204:1207	arg2	pectin					1140:1145	pectin	1140:1145	pectin	1140:1145	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	2	24	theme	amidation	354:362	arg1	degree					364:369	amidation degree	354:369	amidation degree	354:369	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	3	25	theme	aminated	686:693	arg1	pectin					695:700	the corresponding aminated pectin	668:700	the corresponding aminated pectin	668:700	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	26	theme	photoelectron	513:525	arg1	spectrum					527:534	X-ray photoelectron spectrum	507:534	X-ray photoelectron spectrum	507:534	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	27	from	β-C	604:606	arg1	groups					584:589	the amino groups	574:589	the amino groups from α-C and β-C	574:606	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	27	from	β-C	604:606	arg1	aminated					617:624	aminated	617:624	aminated	617:624	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	5	28	theme	dynamic	813:819	arg1	higher					857:862	higher	857:862	higher	857:862	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	5	28	theme	dynamic	813:819	arg1	viscosity					821:829	the dynamic viscosity	809:829	the dynamic viscosity of β-AP	809:837	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	4	29	theme	grafting	715:722	arg1	ratio					724:728	The alanine grafting ratio	703:728	The alanine grafting ratio of α-AP and β-AP	703:745	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	4	29	theme	grafting	715:722	arg1	%					757:757	21.99%	752:757	21.99%	752:757	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	9	30	from	application	1459:1469	arg1	food					1501:1504	low-fat food	1493:1504	low-fat food	1493:1504	The results provide references for the application of amidated pectin in low-fat food.					
36076460	6	31	theme	highest	1080:1086	arg1	modulus					1096:1102	elastic modulus	1088:1102	elastic modulus	1088:1102	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	1	32	theme	β-alanine	250:258	arg1	pectin					269:274	β-alanine amidated pectin	250:274	β-alanine amidated pectin (β-AP)	250:281	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	32	theme	β-alanine	250:258	arg1	β-AP					277:280	β-AP	277:280	β-AP	277:280	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	4	33	theme	alanine	707:713	arg1	ratio					724:728	The alanine grafting ratio	703:728	The alanine grafting ratio of α-AP and β-AP	703:745	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	4	33	theme	alanine	707:713	arg1	%					757:757	21.99%	752:757	21.99%	752:757	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	7	34	theme	food	1225:1228	arg1	field					1216:1220	the field	1212:1220	the field of food	1212:1228	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	2	35	theme	isomer	340:345	arg1	effects					313:319	The effects	309:319	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin	309:410	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	0	36	theme	pectins	24:30	arg1	Preparation					0:10	Preparation	0:10	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.	0:138	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	1	37	theme	amidated	260:267	arg1	pectin					269:274	β-alanine amidated pectin	250:274	β-alanine amidated pectin (β-AP)	250:281	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	37	theme	amidated	260:267	arg1	β-AP					277:280	β-AP	277:280	β-AP	277:280	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	3	38	theme	amino	578:582	arg1	groups					584:589	the amino groups	574:589	the amino groups from α-C and β-C	574:606	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	38	theme	amino	578:582	arg1	aminated					617:624	aminated	617:624	aminated	617:624	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	39	theme	elemental	540:548	arg1	analysis					550:557	elemental analysis	540:557	elemental analysis	540:557	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	40	with	aminated	617:624	arg1	group					644:648	the carboxyl group	631:648	the carboxyl group of pectin to form the corresponding aminated pectin	631:700	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	40	with	aminated	617:624	arg1	pectin					653:658	pectin	653:658	pectin	653:658	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	0	41	theme	amidated	15:22	arg1	pectins					24:30	amidated pectins	15:30	amidated pectins	15:30	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	5	42	theme	acid	912:915	arg1	chain					922:926	amino acid side chain	906:926	amino acid side chain	906:926	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	8	43	theme	methoxy	1299:1305	arg1	pectin					1307:1312	High methoxy pectin	1294:1312	High methoxy pectin (HMP)	1294:1318	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	8	43	theme	methoxy	1299:1305	arg1	HMP					1315:1317	HMP	1315:1317	HMP	1315:1317	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	7	44	theme	delicate	1257:1264	arg1	taste					1266:1270	the smooth and delicate taste	1242:1270	the smooth and delicate taste of fat	1242:1277	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	2	45	theme	physicochemical	375:389	arg1	properties					391:400	physicochemical properties	375:400	physicochemical properties	375:400	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	0	46	theme	enzymatic	40:48	arg1	method					50:55	enzymatic method	40:55	enzymatic method	40:55	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	7	47	theme	carbohydrate-based	1153:1170	arg1	fat					1172:1174	a carbohydrate-based fat substitute	1151:1185	a carbohydrate-based fat substitute	1151:1185	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	7	47	theme	carbohydrate-based	1153:1170	arg1	pectin					1140:1145	pectin	1140:1145	pectin	1140:1145	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	7	48	dep	fat	1172:1174	arg1	substitute					1176:1185	substitute	1176:1185	substitute	1176:1185	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	6	49	theme	α-AP	982:985	arg1	ratio					973:977	the higher alanine grafting ratio	945:977	the higher alanine grafting ratio of α-AP	945:985	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	6	50	theme	grafting	964:971	arg1	ratio					973:977	the higher alanine grafting ratio	945:977	the higher alanine grafting ratio of α-AP	945:985	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	2	51	dep	degree	364:369	arg1	the					350:352	the	350:352	the	350:352	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	6	52	theme	alanine	956:962	arg1	ratio					973:977	the higher alanine grafting ratio	945:977	the higher alanine grafting ratio of α-AP	945:985	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	8	53	from	stability	1354:1362	arg1	system					1412:1417	the composite system	1398:1417	the composite system	1398:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	3	54	theme	magnetic	478:485	arg1	resonance					487:495	proton nuclear magnetic resonance	463:495	proton nuclear magnetic resonance analysis	463:504	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	8	55	theme	hydrogel	1376:1383	arg1	particles					1385:1393	smaller hydrogel particles	1368:1393	smaller hydrogel particles in the composite system	1368:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	5	56	theme	amino	906:910	arg1	chain					922:926	amino acid side chain	906:926	amino acid side chain	906:926	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	8	57	theme	smaller	1368:1374	arg1	particles					1385:1393	smaller hydrogel particles	1368:1393	smaller hydrogel particles in the composite system	1368:1417	Compared with High methoxy pectin (HMP) and β-AP, α-AP had better colloid stability and smaller hydrogel particles in the composite system.					
36076460	3	58	theme	proton	463:468	arg1	resonance					487:495	proton nuclear magnetic resonance	463:495	proton nuclear magnetic resonance analysis	463:504	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	2	59	theme	pectin	405:410	arg1	degree					364:369	amidation degree	354:369	amidation degree	354:369	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	2	59	theme	pectin	405:410	arg1	properties					391:400	physicochemical properties	375:400	physicochemical properties	375:400	The effects of alanine and its isomer on the amidation degree and physicochemical properties of pectin were studied.					
36076460	0	60	from	potential	110:118	arg1	fat					123:125	fat substitutes	123:137	fat substitutes	123:137	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	1	61	used	used	184:187	arg2	α-alanine					155:163	α-alanine	155:163	α-alanine	155:163	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	61	used	used	184:187	arg2	modifiers					192:200	modifiers	192:200	modifiers	192:200	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	61	used	used	184:187	arg2	β-alanine					169:177	β-alanine	169:177	β-alanine	169:177	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	3	62	theme	nuclear	470:476	arg1	resonance					487:495	proton nuclear magnetic resonance	463:495	proton nuclear magnetic resonance analysis	463:504	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	1	63	theme	enzymatic	291:299	arg1	method					301:306	enzymatic method	291:306	enzymatic method	291:306	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	3	64	theme	pectin	653:658	arg1	group					644:648	the carboxyl group	631:648	the carboxyl group of pectin to form the corresponding aminated pectin	631:700	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	64	theme	pectin	653:658	arg1	pectin					653:658	pectin	653:658	pectin	653:658	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	5	65	theme	chain	922:926	arg1	influence					893:901	the influence	889:901	the influence of amino acid side chain	889:926	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	7	66	theme	fat	1275:1277	arg1	taste					1266:1270	the smooth and delicate taste	1242:1270	the smooth and delicate taste of fat	1242:1277	In addition, pectin, as a carbohydrate-based fat substitute, has been widely used in the field of food to simulate the smooth and delicate taste of fat.					
36076460	6	67	theme	higher	949:954	arg1	ratio					973:977	the higher alanine grafting ratio	945:977	the higher alanine grafting ratio of α-AP	945:985	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	4	68	theme	β-AP	742:745	arg1	ratio					724:728	The alanine grafting ratio	703:728	The alanine grafting ratio of α-AP and β-AP	703:745	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	4	68	theme	β-AP	742:745	arg1	%					757:757	21.99%	752:757	21.99%	752:757	The alanine grafting ratio of α-AP and β-AP were 21.99% and 18.92%, respectively.					
36076460	3	69	theme	carboxyl	635:642	arg1	group					644:648	the carboxyl group	631:648	the carboxyl group of pectin to form the corresponding aminated pectin	631:700	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	69	theme	carboxyl	635:642	arg1	pectin					653:658	pectin	653:658	pectin	653:658	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	3	70	dep	Fourier	426:432	arg1	transform					434:442	transform	434:442	transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis	434:557	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	9	71	theme	amidated	1474:1481	arg1	pectin					1483:1488	amidated pectin	1474:1488	amidated pectin	1474:1488	The results provide references for the application of amidated pectin in low-fat food.					
36076460	1	72	theme	α-alanine	213:221	arg1	α-AP					240:243	α-AP	240:243	α-AP	240:243	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	72	theme	α-alanine	213:221	arg1	pectin					232:237	α-alanine amidated pectin	213:237	α-alanine amidated pectin (α-AP)	213:244	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	9	73	theme	low-fat	1493:1499	arg1	food					1501:1504	low-fat food	1493:1504	low-fat food	1493:1504	The results provide references for the application of amidated pectin in low-fat food.					
36076460	3	74	dep	transform	434:442	arg1	infrared					444:451	infrared	444:451	transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis	434:557	Fourier transform infrared spectrum, proton nuclear magnetic resonance analysis, X-ray photoelectron spectrum and elemental analysis indicated that the amino groups from α-C and β-C could be aminated with the carboxyl group of pectin to form the corresponding aminated pectin.					
36076460	5	75	theme	β-AP	834:837	arg1	higher					857:862	higher	857:862	higher	857:862	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	5	75	theme	β-AP	834:837	arg1	viscosity					821:829	the dynamic viscosity	809:829	the dynamic viscosity of β-AP	809:837	The results showed that the dynamic viscosity of β-AP was significantly higher than that of α-AP due to the influence of amino acid side chain.					
36076460	1	76	theme	amidated	223:230	arg1	α-AP					240:243	α-AP	240:243	α-AP	240:243	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	1	76	theme	amidated	223:230	arg1	pectin					232:237	α-alanine amidated pectin	213:237	α-alanine amidated pectin (α-AP)	213:244	In this paper, α-alanine and β-alanine were used as modifiers to prepare α-alanine amidated pectin (α-AP) and β-alanine amidated pectin (β-AP) through enzymatic method.					
36076460	0	77	dep	Preparation	0:10	arg1	Structures					58:67	Structures	58:67	Structures	58:67	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	0	77	dep	Preparation	0:10	arg1	properties					79:88	hydrogel properties	70:88	hydrogel properties	70:88	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	0	77	dep	Preparation	0:10	arg1	application					98:108	its application	94:108	its application potential in fat substitutes	94:137	Preparation of amidated pectins through enzymatic method: Structures, hydrogel properties and its application potential in fat substitutes.					
36076460	6	78	contain	has	1072:1074	arg1	it					1064:1065	it	1064:1065	it	1064:1065	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	6	78	contain	has	1072:1074	arg2	capacity					1117:1124	swelling capacity	1108:1124	swelling capacity	1108:1124	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
36076460	6	78	contain	has	1072:1074	arg2	modulus					1096:1102	elastic modulus	1088:1102	elastic modulus	1088:1102	However, due to the higher alanine grafting ratio of α-AP, the strength of hydrogel prepared by α-AP was higher than that of β-AP, and it also has the highest elastic modulus and swelling capacity.					
35550772	0	0	theme	cellulose	58:66	arg1	nanofibers					68:77	cellulose nanofibers	58:77	cellulose nanofibers	58:77	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	3	1	theme	metabolic	632:640	arg1	bioactivity					642:652	metabolic bioactivity	632:652	metabolic bioactivity	632:652	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	2	2	theme	3D	304:305	arg1	stamp					315:319	a 3D printed stamp	302:319	a 3D printed stamp	302:319	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	1	3	theme	transparent	131:141	arg1	sheet					152:156	a transparent hydrogel sheet	129:156	a transparent hydrogel sheet	129:156	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	3	4	from	Microalgae	448:457	arg1	hydrogel					466:473	the hydrogel	462:473	the hydrogel	462:473	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	0	5	theme	nanofibers	68:77	arg1	sheet					49:53	a living hydrogel sheet	31:53	a living hydrogel sheet of cellulose nanofibers	31:77	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	5	6	theme	simple	800:805	arg1	fabrication					807:817	the simple fabrication	796:817	the simple fabrication of fluidic channels in the hydrogel	796:853	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	3	7	theme	flat	661:664	arg1	sheet					666:670	a flat sheet	659:670	a flat sheet cultured in a bulk solution	659:698	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	5	8	theme	diverse	873:879	arg1	animal					919:924	animal	919:924	animal	919:924	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	8	theme	diverse	873:879	arg1	organisms					888:896	diverse living organisms	873:896	diverse living organisms	873:896	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	8	theme	diverse	873:879	arg1	bacteria					909:916	bacteria	909:916	bacteria	909:916	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	8	theme	diverse	873:879	arg1	cells					937:941	plant cells	931:941	plant cells	931:941	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	1	9	theme	hydrogel	143:150	arg1	sheet					152:156	a transparent hydrogel sheet	129:156	a transparent hydrogel sheet	129:156	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	5	10	theme	living	881:886	arg1	animal					919:924	animal	919:924	animal	919:924	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	10	theme	living	881:886	arg1	organisms					888:896	diverse living organisms	873:896	diverse living organisms	873:896	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	10	theme	living	881:886	arg1	bacteria					909:916	bacteria	909:916	bacteria	909:916	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	5	10	theme	living	881:886	arg1	cells					937:941	plant cells	931:941	plant cells	931:941	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	2	11	theme	living	390:395	arg1	cells					397:401	living cells	390:401	living cells	390:401	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	4	12	theme	artificial	765:774	arg1	plant					776:780	a whole artificial plant	757:780	a whole artificial plant	757:780	This mimicry of the plant leaf provides a potential for a whole artificial plant.					
35550772	4	13	theme	whole	759:763	arg1	plant					776:780	a whole artificial plant	757:780	a whole artificial plant	757:780	This mimicry of the plant leaf provides a potential for a whole artificial plant.					
35550772	5	14	theme	plant	931:935	arg1	cells					937:941	plant cells	931:941	plant cells	931:941	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	1	15	theme	vein	159:162	arg1	structures					164:173	vein structures	159:173	vein structures	159:173	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	0	16	theme	plant	15:19	arg1	leaf					21:24	the plant leaf	11:24	the plant leaf	11:24	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	3	17	theme	ambient	504:510	arg1	condition					512:520	ambient condition	504:520	ambient condition for a long period	504:538	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	2	18	theme	channels	354:361	arg1	formation					333:341	the formation	329:341	the formation of fluidic channels in the hydrogel	329:377	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	2	19	theme	toxic	411:415	arg1	chemistry					417:425	toxic chemistry	411:425	toxic chemistry	411:425	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	0	20	theme	leaf	21:24	arg1	Mimicry					0:6	Mimicry	0:6	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.	0:78	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	4	21	theme	leaf	727:730	arg1	mimicry					706:712	This mimicry	701:712	This mimicry of the plant leaf	701:730	This mimicry of the plant leaf provides a potential for a whole artificial plant.					
35550772	2	22	theme	fluidic	346:352	arg1	channels					354:361	fluidic channels	346:361	fluidic channels	346:361	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	0	23	theme	living	33:38	arg1	sheet					49:53	a living hydrogel sheet	31:53	a living hydrogel sheet of cellulose nanofibers	31:77	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	2	24	theme	drying	432:437	arg1	process					439:445	a drying process	430:445	a drying process	430:445	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	5	25	from	fabrication	807:817	arg1	hydrogel					846:853	the hydrogel	842:853	the hydrogel	842:853	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	3	26	theme	bulk	686:689	arg1	solution					691:698	a bulk solution	684:698	a bulk solution	684:698	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	3	27	theme	nutrient	576:583	arg1	supply					566:571	the continuous supply	551:571	the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution	551:698	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	3	28	theme	long	528:531	arg1	period					533:538	a long period	526:538	a long period	526:538	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	5	29	theme	fluidic	822:828	arg1	channels					830:837	fluidic channels	822:837	fluidic channels	822:837	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	3	30	theme	continuous	555:564	arg1	supply					566:571	the continuous supply	551:571	the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution	551:698	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	2	31	from	formation	333:341	arg1	hydrogel					370:377	the hydrogel	366:377	the hydrogel	366:377	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	2	32	theme	simple	278:283	arg1	imprinting					285:294	A simple imprinting	276:294	A simple imprinting using a 3D printed stamp	276:319	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	1	33	theme	photosynthetic	182:195	arg1	system					197:202	a photosynthetic system	180:202	a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass	180:273	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	0	34	with	Mimicry	0:6	arg1	sheet					49:53	a living hydrogel sheet	31:53	a living hydrogel sheet of cellulose nanofibers	31:77	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	1	35	theme	artificial	102:111	arg1	leaf					113:116	an artificial leaf	99:116	an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass	99:273	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	5	36	theme	channels	830:837	arg1	fabrication					807:817	the simple fabrication	796:817	the simple fabrication of fluidic channels in the hydrogel	796:853	In addition, the simple fabrication of fluidic channels in the hydrogel can be applied to diverse living organisms, including bacteria, animal, and plant cells.					
35550772	3	37	from	channels	594:601	arg1	supply					566:571	the continuous supply	551:571	the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution	551:698	Microalgae in the hydrogel grows and proliferates under ambient condition for a long period because of the continuous supply of nutrient from the channels, which is more effective for metabolic bioactivity than a flat sheet cultured in a bulk solution.					
35550772	4	38	theme	plant	721:725	arg1	leaf					727:730	the plant leaf	717:730	the plant leaf	717:730	This mimicry of the plant leaf provides a potential for a whole artificial plant.					
35550772	0	39	theme	hydrogel	40:47	arg1	sheet					49:53	a living hydrogel sheet	31:53	a living hydrogel sheet of cellulose nanofibers	31:77	Mimicry of the plant leaf with a living hydrogel sheet of cellulose nanofibers.					
35550772	2	40	theme	printed	307:313	arg1	stamp					315:319	a 3D printed stamp	302:319	a 3D printed stamp	302:319	A simple imprinting using a 3D printed stamp enabled the formation of fluidic channels in the hydrogel, embedding living cells without toxic chemistry or a drying process.					
35550772	1	41	theme	cellulose	210:218	arg1	CNFs					232:235	CNFs	232:235	CNFs	232:235	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
35550772	1	41	theme	cellulose	210:218	arg1	nanofibers					220:229	cellulose nanofibers	210:229	cellulose nanofibers (CNFs) which can be produced from a biomass	210:273	Here, we composite an artificial leaf comprising a transparent hydrogel sheet, vein structures, and a photosynthetic system using cellulose nanofibers (CNFs) which can be produced from a biomass.					
36849132	6	0	theme	other	1037:1041	arg1	organs					1049:1054	other axial organs	1037:1054	other axial organs	1037:1054	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	0	theme	other	1037:1041	arg1	stems					1077:1081	stems	1077:1081	stems	1077:1081	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	0	theme	other	1037:1041	arg1	petioles					1065:1072	petioles	1065:1072	petioles	1065:1072	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	2	1	theme	wall	325:328	arg1	structure					330:338	the cell wall structure	316:338	the cell wall structure of CMCs that contributes to the movement	316:379	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	6	2	from	that	1029:1032	arg1	different					1014:1022	different	1014:1022	different	1014:1022	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	2	from	that	1029:1032	arg1	composition					988:998	the cell wall composition	974:998	the cell wall composition of pulvini	974:1009	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	3	3	theme	low	494:496	arg1	levels					498:503	low levels	494:503	low levels of cellulose deposition	494:527	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	1	4	theme	motor	121:125	arg1	CMCs					134:137	CMCs	134:137	CMCs	134:137	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	1	4	theme	motor	121:125	arg1	cells					127:131	The cortical motor cells	108:131	The cortical motor cells (CMCs) in a legume pulvinus	108:159	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	7	5	from	amount	1196:1201	arg1	pulvini					1227:1233	pulvini	1227:1233	pulvini	1227:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	4	6	dep	slits	706:710	arg1	them					691:694	them	691:694	them	691:694	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	10	7	theme	deformation	1735:1745	arg1	knowledge					1690:1698	knowledge	1690:1698	knowledge of repetitive and reversible organ deformation	1690:1745	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	2	8	theme	osmotic	289:295	arg1	regulation					297:306	the underlying osmotic regulation proper	274:313	the underlying osmotic regulation proper	274:313	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	8	9	from	slits	1391:1395	arg1	presence					1404:1411	the presence	1400:1411	the presence of turgor pressure	1400:1430	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	1	10	theme	reversible	173:182	arg1	deformation					184:194	the reversible deformation	169:194	the reversible deformation in leaf movement that is driven by changes in turgor pressure	169:256	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	10	11	theme	CMCs	1674:1677	arg1	structure					1661:1669	a distinctive cell wall structure	1637:1669	a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall	1637:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	10	11	theme	CMCs	1674:1677	arg1	function					1787:1794	function	1787:1794	function	1787:1794	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	10	11	theme	CMCs	1674:1677	arg1	diversity					1773:1781	diversity	1773:1781	diversity	1773:1781	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	5	12	theme	homogalacturonan	770:785	arg1	slits					803:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	4	13	theme	cell	648:651	arg1	walls					653:657	any other primary cell walls	630:657	any other primary cell walls reported so far	630:673	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	1	14	from	deformation	184:194	arg1	movement					204:211	leaf movement	199:211	leaf movement	199:211	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	8	15	theme	turgor	1416:1421	arg1	pressure					1423:1430	turgor pressure	1416:1430	turgor pressure	1416:1430	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	2	16	dep	regulation	297:306	arg1	contrast					262:269	contrast	262:269	contrast	262:269	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	9	17	theme	CMCs	1455:1458	arg1	slices					1445:1450	tissue slices	1438:1450	tissue slices of CMCs	1438:1458	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	4	18	theme	other	634:638	arg1	walls					653:657	any other primary cell walls	630:657	any other primary cell walls reported so far	630:673	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	0	19	theme	Legume	89:94	arg1	Cell					102:105	a Legume Motor Cell	87:105	a Legume Motor Cell	87:105	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	1	20	theme	legume	145:150	arg1	pulvinus					152:159	a legume pulvinus	143:159	a legume pulvinus	143:159	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	6	21	theme	spectroscopy	937:948	arg1	analysis					950:957	Fourier-transform infrared spectroscopy analysis	910:957	Fourier-transform infrared spectroscopy analysis	910:957	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	7	22	theme	pectin-rich	1142:1152	arg1	pulvini					1130:1136	pulvini	1130:1136	pulvini	1130:1136	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	7	22	theme	pectin-rich	1142:1152	arg1	organs					1154:1159	pectin-rich organs	1142:1159	pectin-rich organs like developing stems	1142:1181	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	10	23	theme	repetitive	1703:1712	arg1	deformation					1735:1745	repetitive and reversible organ deformation	1703:1745	repetitive and reversible organ deformation	1703:1745	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	9	24	theme	osmotic	1504:1510	arg1	conditions					1512:1521	different extracellular osmotic conditions	1480:1521	different extracellular osmotic conditions	1480:1521	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	5	25	theme	homogalacturonan	860:875	arg1	deposition					821:830	a low deposition	815:830	a low deposition of highly methyl-esterified homogalacturonan	815:875	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	0	26	theme	Pulvinar	0:7	arg1	Slits					9:13	Pulvinar Slits	0:13	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.	0:106	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	7	27	theme	developing	1254:1263	arg1	stems					1265:1269	developing stems	1254:1269	developing stems	1254:1269	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	8	28	theme	anisotropic	1331:1341	arg1	extension					1343:1351	anisotropic extension	1331:1351	anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure	1331:1430	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	10	29	theme	distinctive	1639:1649	arg1	structure					1661:1669	a distinctive cell wall structure	1637:1669	a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall	1637:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	7	30	theme	monosaccharide	1094:1107	arg1	analysis					1109:1116	monosaccharide analysis	1094:1116	monosaccharide analysis	1094:1116	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	1	31	theme	cortical	112:119	arg1	CMCs					134:137	CMCs	134:137	CMCs	134:137	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	1	31	theme	cortical	112:119	arg1	cells					127:131	The cortical motor cells	108:131	The cortical motor cells (CMCs) in a legume pulvinus	108:159	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	10	32	theme	cell	1809:1812	arg1	wall					1814:1817	the plant cell wall	1799:1817	the plant cell wall	1799:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	3	33	with	slits	483:487	arg1	levels					498:503	low levels	494:503	low levels of cellulose deposition	494:527	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	7	34	from	pulvini	1227:1233	arg1	greater					1238:1244	greater	1238:1244	greater	1238:1244	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	7	34	from	pulvini	1227:1233	arg1	amount					1196:1201	the amount	1192:1201	the amount of galacturonic acid in pulvini	1192:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	7	34	from	pulvini	1227:1233	arg1	acid					1219:1222	galacturonic acid	1206:1222	galacturonic acid in pulvini	1206:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	6	35	theme	wall	983:986	arg1	different					1014:1022	different	1014:1022	different	1014:1022	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	35	theme	wall	983:986	arg1	composition					988:998	the cell wall composition	974:998	the cell wall composition of pulvini	974:1009	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	8	36	theme	direction	1360:1368	arg1	perpendicular					1370:1382	the direction perpendicular	1356:1382	the direction perpendicular	1356:1382	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	2	37	theme	cell	320:323	arg1	structure					330:338	the cell wall structure	316:338	the cell wall structure of CMCs that contributes to the movement	316:379	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	0	38	theme	Pectin-Rich	61:71	arg1	Structures					73:82	Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures	16:82	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.	0:106	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	4	39	theme	pulvinar	697:704	arg1	slits					706:710	pulvinar slits	697:710	pulvinar slits	697:710	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	10	40	theme	wall	1656:1659	arg1	structure					1661:1669	a distinctive cell wall structure	1637:1669	a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall	1637:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	7	41	theme	galacturonic	1206:1217	arg1	acid					1219:1222	galacturonic acid	1206:1222	galacturonic acid in pulvini	1206:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	3	42	theme	CMCs	458:461	arg1	wall					450:453	the cell wall	441:453	the cell wall of CMCs	441:461	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	5	43	theme	pulvinar	794:801	arg1	slits					803:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	4	44	dep	unique	597:602	arg1	named					685:689	named	685:689	named them "pulvinar slits	685:710	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	4	44	dep	unique	597:602	arg1	"					712:712	"	712:712	"	712:712	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	6	45	theme	axial	1043:1047	arg1	organs					1049:1054	other axial organs	1037:1054	other axial organs	1037:1054	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	45	theme	axial	1043:1047	arg1	stems					1077:1081	stems	1077:1081	stems	1077:1081	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	45	theme	axial	1043:1047	arg1	petioles					1065:1072	petioles	1065:1072	petioles	1065:1072	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	4	46	from	that	622:625	arg1	distinct					608:615	distinct	608:615	distinct	608:615	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	1	47	theme	turgor	242:247	arg1	pressure					249:256	turgor pressure	242:256	turgor pressure	242:256	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	3	48	theme	circumferential	467:481	arg1	slits					483:487	circumferential slits	467:487	circumferential slits	467:487	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	5	49	theme	inside	787:792	arg1	slits					803:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	10	50	dep	diversity	1773:1781	arg1	the					1758:1760	the	1758:1760	the	1758:1760	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	3	51	theme	cellulose	508:516	arg1	deposition					518:527	cellulose deposition	508:527	cellulose deposition	508:527	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	8	52	from	extension	1343:1351	arg1	perpendicular					1370:1382	the direction perpendicular	1356:1382	the direction perpendicular	1356:1382	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	7	53	from	acid	1219:1222	arg1	pulvini					1227:1233	pulvini	1227:1233	pulvini	1227:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	2	54	theme	underlying	278:287	arg1	regulation					297:306	the underlying osmotic regulation proper	274:313	the underlying osmotic regulation proper	274:313	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	3	55	theme	deposition	518:527	arg1	levels					498:503	low levels	494:503	low levels of cellulose deposition	494:527	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	9	56	theme	different	1480:1488	arg1	conditions					1512:1521	different extracellular osmotic conditions	1480:1521	different extracellular osmotic conditions	1480:1521	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	1	57	from	changes	231:237	arg1	pressure					249:256	turgor pressure	242:256	turgor pressure	242:256	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	10	58	theme	structural	1762:1771	arg1	diversity					1773:1781	diversity	1773:1781	diversity	1773:1781	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	5	59	theme	de-methyl-esterified	749:768	arg1	slits					803:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	de-methyl-esterified homogalacturonan inside pulvinar slits	749:807	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	9	60	theme	tissue	1438:1443	arg1	slices					1445:1450	tissue slices	1438:1450	tissue slices of CMCs	1438:1458	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	8	61	theme	pressure	1423:1430	arg1	presence					1404:1411	the presence	1400:1411	the presence of turgor pressure	1400:1430	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	4	62	theme	primary	640:646	arg1	walls					653:657	any other primary cell walls	630:657	any other primary cell walls reported so far	630:673	This structure is unique and distinct from that of any other primary cell walls reported so far; thus, we named them "pulvinar slits."					
36849132	3	63	theme	legume	563:568	arg1	species					570:576	legume species	563:576	legume species	563:576	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	5	64	theme	methyl-esterified	842:858	arg1	homogalacturonan					860:875	highly methyl-esterified homogalacturonan	835:875	highly methyl-esterified homogalacturonan	835:875	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	10	65	theme	organ	1729:1733	arg1	deformation					1735:1745	repetitive and reversible organ deformation	1703:1745	repetitive and reversible organ deformation	1703:1745	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	6	66	theme	cell	978:981	arg1	different					1014:1022	different	1014:1022	different	1014:1022	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	66	theme	cell	978:981	arg1	composition					988:998	the cell wall composition	974:998	the cell wall composition of pulvini	974:1009	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	7	67	theme	developing	1166:1175	arg1	stems					1177:1181	developing stems	1166:1181	developing stems	1166:1181	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	0	68	theme	Motor	96:100	arg1	Cell					102:105	a Legume Motor Cell	87:105	a Legume Motor Cell	87:105	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	5	69	theme	low	817:819	arg1	deposition					821:830	a low deposition	815:830	a low deposition of highly methyl-esterified homogalacturonan	815:875	Notably, we predominantly detected de-methyl-esterified homogalacturonan inside pulvinar slits, with a low deposition of highly methyl-esterified homogalacturonan, as with cellulose.					
36849132	3	70	contain	has	463:465	arg2	slits					483:487	circumferential slits	467:487	circumferential slits	467:487	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	3	70	contain	has	463:465	arg1	wall					450:453	the cell wall	441:453	the cell wall of CMCs	441:461	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	9	71	theme	extracellular	1490:1502	arg1	conditions					1512:1521	different extracellular osmotic conditions	1480:1521	different extracellular osmotic conditions	1480:1521	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	10	72	theme	reversible	1718:1727	arg1	deformation					1735:1745	repetitive and reversible organ deformation	1703:1745	repetitive and reversible organ deformation	1703:1745	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	6	73	theme	infrared	928:935	arg1	analysis					950:957	Fourier-transform infrared spectroscopy analysis	910:957	Fourier-transform infrared spectroscopy analysis	910:957	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	0	74	from	Structures	73:82	arg1	Cell					102:105	a Legume Motor Cell	87:105	a Legume Motor Cell	87:105	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	8	75	theme	Computer	1272:1279	arg1	modeling					1281:1288	Computer modeling	1272:1288	Computer modeling	1272:1288	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	2	76	theme	proper	308:313	arg1	regulation					297:306	the underlying osmotic regulation proper	274:313	the underlying osmotic regulation proper	274:313	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	6	77	theme	Fourier-transform	910:926	arg1	analysis					950:957	Fourier-transform infrared spectroscopy analysis	910:957	Fourier-transform infrared spectroscopy analysis	910:957	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	9	78	theme	pulvinar	1524:1531	arg1	slits					1533:1537	pulvinar slits	1524:1537	pulvinar slits	1524:1537	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	8	79	theme	pulvinar	1305:1312	arg1	slits					1314:1318	pulvinar slits	1305:1318	pulvinar slits	1305:1318	Computer modeling suggested that pulvinar slits facilitate anisotropic extension in the direction perpendicular to the slits in the presence of turgor pressure.					
36849132	0	80	theme	Cellulose-deficient	16:34	arg1	Structures					73:82	Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures	16:82	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.	0:106	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	1	81	from	cells	127:131	arg1	pulvinus					152:159	a legume pulvinus	143:159	a legume pulvinus	143:159	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	6	82	theme	pulvini	1003:1009	arg1	different					1014:1022	different	1014:1022	different	1014:1022	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	6	82	theme	pulvini	1003:1009	arg1	composition					988:998	the cell wall composition	974:998	the cell wall composition of pulvini	974:1009	In addition, Fourier-transform infrared spectroscopy analysis indicated that the cell wall composition of pulvini is different from that of other axial organs, such as petioles or stems.					
36849132	10	83	theme	wall	1814:1817	arg1	structure					1661:1669	a distinctive cell wall structure	1637:1669	a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall	1637:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	10	83	theme	wall	1814:1817	arg1	function					1787:1794	function	1787:1794	function	1787:1794	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	10	83	theme	wall	1814:1817	arg1	diversity					1773:1781	diversity	1773:1781	diversity	1773:1781	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	2	84	theme	CMCs	343:346	arg1	structure					330:338	the cell wall structure	316:338	the cell wall structure of CMCs that contributes to the movement	316:379	In contrast to the underlying osmotic regulation proper, the cell wall structure of CMCs that contributes to the movement has yet to be characterized in detail.					
36849132	0	85	theme	De-Methyl-Esterified	40:59	arg1	Structures					73:82	Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures	16:82	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.	0:106	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36849132	1	86	theme	leaf	199:202	arg1	movement					204:211	leaf movement	199:211	leaf movement	199:211	The cortical motor cells (CMCs) in a legume pulvinus execute the reversible deformation in leaf movement that is driven by changes in turgor pressure.					
36849132	9	87	theme	opening	1553:1559	arg1	width					1561:1565	their opening width	1547:1565	their opening width	1547:1565	When tissue slices of CMCs were transferred to different extracellular osmotic conditions, pulvinar slits altered their opening width, indicating their deformability.					
36849132	10	88	theme	plant	1803:1807	arg1	wall					1814:1817	the plant cell wall	1799:1817	the plant cell wall	1799:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	7	89	theme	acid	1219:1222	arg1	greater					1238:1244	greater	1238:1244	greater	1238:1244	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	7	89	theme	acid	1219:1222	arg1	amount					1196:1201	the amount	1192:1201	the amount of galacturonic acid in pulvini	1192:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	7	89	theme	acid	1219:1222	arg1	acid					1219:1222	galacturonic acid	1206:1222	galacturonic acid in pulvini	1206:1233	Moreover, monosaccharide analysis showed that pulvini are pectin-rich organs like developing stems and that the amount of galacturonic acid in pulvini is greater than in developing stems.					
36849132	3	90	theme	cell	445:448	arg1	wall					450:453	the cell wall	441:453	the cell wall of CMCs	441:461	Here, we report that the cell wall of CMCs has circumferential slits with low levels of cellulose deposition, which are widely conserved among legume species.					
36849132	10	91	theme	cell	1651:1654	arg1	structure					1661:1669	a distinctive cell wall structure	1637:1669	a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall	1637:1817	In this study, we thus characterized a distinctive cell wall structure of CMCs, adding to knowledge of repetitive and reversible organ deformation as well as the structural diversity and function of the plant cell wall.					
36849132	0	92	dep	Slits	9:13	arg1	Structures					73:82	Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures	16:82	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.	0:106	Pulvinar Slits: Cellulose-deficient and De-Methyl-Esterified Pectin-Rich Structures in a Legume Motor Cell.					
36030633	4	0	from	structures	585:594	arg1	strains					646:652	five strains	641:652	five strains	641:652	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	1	1	theme	human	313:317	arg1	mouth					319:323	the human mouth	309:323	the human mouth where it causes periodontitis	309:353	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	3	2	theme	Cell	483:486	arg1	structures					496:505	Cell surface structures	483:505	Cell surface structures of the bacterium	483:522	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36030633	0	3	theme	monoclonal	200:209	arg1	antibodies					211:220	mouse monoclonal antibodies	194:220	mouse monoclonal antibodies specific to the O-antigens	194:247	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	3	4	theme	surface	488:494	arg1	structures					496:505	Cell surface structures	483:505	Cell surface structures of the bacterium	483:522	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36030633	0	5	from	alditol	135:141	arg1	chain					169:173	the main chain	160:173	the main chain	160:173	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	6	theme	main	164:167	arg1	chain					169:173	the main chain	160:173	the main chain	160:173	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	7	theme	mouse	194:198	arg1	antibodies					211:220	mouse monoclonal antibodies	194:220	mouse monoclonal antibodies specific to the O-antigens	194:247	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	4	8	theme	lipopolysaccharide	603:620	arg1	OPS					631:633	the lipopolysaccharide O-chain (OPS)	599:634	the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	599:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	0	9	theme	specific	222:229	arg1	antibodies					211:220	mouse monoclonal antibodies	194:220	mouse monoclonal antibodies specific to the O-antigens	194:247	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	4	10	from	strains	646:652	arg1	structures					585:594	four new structures	576:594	four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	576:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	10	from	strains	646:652	arg1	OPS					631:633	the lipopolysaccharide O-chain (OPS)	599:634	the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	599:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	5	11	theme	common	788:793	arg1	sequence					795:802	a common sequence	786:802	a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain	786:862	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	0	12	theme	antibodies	211:220	arg1	development					179:189	development	179:189	development of mouse monoclonal antibodies specific to the O-antigens	179:247	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	12	theme	antibodies	211:220	arg1	phosphate					147:155	phosphate	147:155	phosphate	147:155	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	12	theme	antibodies	211:220	arg1	alditol					135:141	alditol	135:141	alditol	135:141	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	13	dep	CC2_6JVN3	83:91	arg1	structure					4:12	The structure	0:12	The structure of the LPS O-chain from five Fusobacterium nucleatum strains	0:73	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	5	14	theme	hexose-diaminofucose-hexitol-phosphate	807:844	arg1	sequence					795:802	a common sequence	786:802	a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain	786:862	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	3	15	theme	bacterium	514:522	arg1	structures					496:505	Cell surface structures	483:505	Cell surface structures of the bacterium	483:522	Cell surface structures of the bacterium could be implicated in pathogenesis.					
36030633	0	16	contain	containing	124:133	arg2	development					179:189	development	179:189	development of mouse monoclonal antibodies specific to the O-antigens	179:247	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	16	contain	containing	124:133	arg1	CC2_6JVN3					83:91	CC2_6JVN3	83:91	CC2_6JVN3	83:91	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	16	contain	containing	124:133	arg2	alditol					135:141	alditol	135:141	alditol	135:141	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	16	contain	containing	124:133	arg1	CC2_1JVN3					105:113	CC2_1JVN3	105:113	CC2_1JVN3	105:113	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	16	contain	containing	124:133	arg2	phosphate					147:155	phosphate	147:155	phosphate	147:155	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	4	17	theme	OPS	631:633	arg1	structures					585:594	four new structures	576:594	four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	576:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	1	18	theme	Fusobacterium	250:262	arg1	bacterium					290:298	an anaerobic bacterium	277:298	an anaerobic bacterium found in the human mouth where it causes periodontitis	277:353	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	1	18	theme	Fusobacterium	250:262	arg1	nucleatum					264:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	4	19	dep	F.	657:658	arg1	nucleatum					660:668	F. nucleatum	657:668	F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996	657:716	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	19	dep	F.	657:658	arg1	CC2_6JVN3					678:686	CC2_6JVN3	678:686	CC2_6JVN3	678:686	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	19	dep	F.	657:658	arg1	CC2_1JVN3					700:708	CC2_1JVN3	700:708	CC2_1JVN3	700:708	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	19	dep	F.	657:658	arg1	CC2_3FMU1					689:697	CC2_3FMU1	689:697	CC2_3FMU1	689:697	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	5	20	theme	main	853:856	arg1	chain					858:862	the main chain	849:862	the main chain	849:862	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	5	21	theme	structures	770:779	arg1	Three					752:756	Three	752:756	Three	752:756	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	5	21	theme	structures	770:779	arg1	structures					770:779	the four structures	761:779	the four structures	761:779	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	4	22	attach	isolated	719:726	arg2	strains					646:652	five strains	641:652	five strains	641:652	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	22	attach	isolated	719:726	arg1	tissues					743:749	cancerous tissues	733:749	cancerous tissues	733:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	23	theme	O-chain	622:628	arg1	OPS					631:633	the lipopolysaccharide O-chain (OPS)	599:634	the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	599:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	4	24	theme	cancerous	733:741	arg1	tissues					743:749	cancerous tissues	733:749	cancerous tissues	733:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	5	25	contain	have	781:784	arg1	Three					752:756	Three	752:756	Three	752:756	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	5	25	contain	have	781:784	arg1	structures					770:779	the four structures	761:779	the four structures	761:779	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	5	25	contain	have	781:784	arg2	sequence					795:802	a common sequence	786:802	a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain	786:862	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	1	26	located	found	300:304	arg1	mouth					319:323	the human mouth	309:323	the human mouth where it causes periodontitis	309:353	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	1	26	located	found	300:304	arg2	bacterium					290:298	an anaerobic bacterium	277:298	an anaerobic bacterium found in the human mouth where it causes periodontitis	277:353	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	1	26	located	found	300:304	arg2	nucleatum					264:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	2	27	theme	cancer	388:393	arg1	tissues					395:401	colorectal cancer tissues	377:401	colorectal cancer tissues	377:401	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	0	28	theme	O-chain	25:31	arg1	structure					4:12	The structure	0:12	The structure of the LPS O-chain from five Fusobacterium nucleatum strains	0:73	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	29	from	phosphate	147:155	arg1	chain					169:173	the main chain	160:173	the main chain	160:173	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	0	30	from	strains	67:73	arg1	structure					4:12	The structure	0:12	The structure of the LPS O-chain from five Fusobacterium nucleatum strains	0:73	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	2	31	theme	colorectal	377:386	arg1	tissues					395:401	colorectal cancer tissues	377:401	colorectal cancer tissues	377:401	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	0	32	theme	LPS	21:23	arg1	O-chain					25:31	the LPS O-chain	17:31	the LPS O-chain	17:31	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	1	33	theme	anaerobic	280:288	arg1	bacterium					290:298	an anaerobic bacterium	277:298	an anaerobic bacterium found in the human mouth where it causes periodontitis	277:353	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	1	33	theme	anaerobic	280:288	arg1	nucleatum					264:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum	250:272	Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis.					
36030633	5	34	from	sequence	795:802	arg1	chain					858:862	the main chain	849:862	the main chain	849:862	Three of the four structures have a common sequence of hexose-diaminofucose-hexitol-phosphate in the main chain.					
36030633	0	35	from	development	179:189	arg1	chain					169:173	the main chain	160:173	the main chain	160:173	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	2	36	theme	pregnancy	422:430	arg1	stillbirths					470:480	stillbirths	470:480	stillbirths	470:480	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	2	36	theme	pregnancy	422:430	arg1	complications					432:444	pregnancy complications	422:444	pregnancy complications	422:444	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	2	36	theme	pregnancy	422:430	arg1	pre-term					457:464	pre-term	457:464	pre-term	457:464	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	2	37	located	found	368:372	arg2	It					356:357	It	356:357	It	356:357	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	2	37	located	found	368:372	arg1	tissues					395:401	colorectal cancer tissues	377:401	colorectal cancer tissues	377:401	It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and stillbirths.					
36030633	4	38	theme	new	581:583	arg1	structures					585:594	four new structures	576:594	four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues	576:749	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	0	39	theme	nucleatum	57:65	arg1	strains					67:73	five Fusobacterium nucleatum strains	38:73	five Fusobacterium nucleatum strains	38:73	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36030633	4	40	theme	F.	657:658	arg1	strains					646:652	five strains	641:652	five strains	641:652	Here we report four new structures of the lipopolysaccharide O-chain (OPS) from five strains of F. nucleatum CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, isolated from cancerous tissues.					
36030633	0	41	theme	Fusobacterium	43:55	arg1	strains					67:73	five Fusobacterium nucleatum strains	38:73	five Fusobacterium nucleatum strains	38:73	The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens.					
36719417	2	0	theme	infected	394:401	arg1	wounds					403:408	infected wounds	394:408	infected wounds	394:408	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36719417	0	1	theme	Wound	109:113	arg1	Healing					115:121	Infected Wound Healing	100:121	Infected Wound Healing	100:121	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	1	2	theme	multifunctional	178:192	arg1	dressings					200:208	multifunctional wound dressings	178:208	multifunctional wound dressings that can combat infection and prompt wound healing simultaneously	178:274	In clinical practice, it has become urgent to develop multifunctional wound dressings that can combat infection and prompt wound healing simultaneously.					
36719417	4	3	theme	bacteria-infected	1011:1027	arg1	wounds					1029:1034	bacteria-infected wounds	1011:1034	bacteria-infected wounds in vivo	1011:1042	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	4	theme	endothelial	771:781	arg1	cells					783:787	endothelial cells	771:787	endothelial cells	771:787	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	2	5	theme	polydopamine/alginate/nanoselenium	306:339	arg1	hydrogel					351:358	a polydopamine/alginate/nanoselenium composite hydrogel	304:358	a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds	304:408	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36719417	2	5	theme	polydopamine/alginate/nanoselenium	306:339	arg1	Alg-PDA-Se					361:370	Alg-PDA-Se	361:370	Alg-PDA-Se	361:370	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36719417	4	6	theme	mild	829:832	arg1	temperature					834:844	mild temperature	829:844	mild temperature	829:844	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	4	7	theme	in	1036:1037	arg1	wounds					1029:1034	bacteria-infected wounds	1011:1034	bacteria-infected wounds in vivo	1011:1042	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	1	8	theme	wound	194:198	arg1	dressings					200:208	multifunctional wound dressings	178:208	multifunctional wound dressings that can combat infection and prompt wound healing simultaneously	178:274	In clinical practice, it has become urgent to develop multifunctional wound dressings that can combat infection and prompt wound healing simultaneously.					
36719417	4	9	theme	wounds	1029:1034	arg1	healing					1000:1006	the healing	996:1006	the healing of bacteria-infected wounds in vivo	996:1042	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	0	10	theme	Low-Dose	61:68	arg1	Nanoselenium					70:81	Low-Dose Nanoselenium	61:81	Low-Dose Nanoselenium	61:81	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	4	11	theme	Se	862:863	arg1	NPs					865:867	low-dosage Se NPs	851:867	low-dosage Se NPs	851:867	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	12	theme	photothermal	501:512	arg1	properties					514:523	controllable near-infrared photothermal properties	474:523	controllable near-infrared photothermal properties	474:523	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	0	13	theme	Heat-Assisted	5:17	arg1	Hydrogel					41:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	4	14	dep	aureus	932:937	arg1	aureus					943:948	S. aureus	940:948	S. aureus	940:948	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	15	theme	pro-migration	645:657	arg1	performances					679:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	0	16	theme	Mild	0:3	arg1	Hydrogel					41:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	4	17	theme	low-dosage	851:860	arg1	NPs					865:867	low-dosage Se NPs	851:867	low-dosage Se NPs	851:867	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	18	theme	controllable	474:485	arg1	properties					514:523	controllable near-infrared photothermal properties	474:523	controllable near-infrared photothermal properties	474:523	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	4	19	dep	in	1036:1037	arg1	vivo					1039:1042	vivo	1039:1042	vivo	1039:1042	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	1	20	theme	clinical	127:134	arg1	practice					136:143	clinical practice	127:143	clinical practice	127:143	In clinical practice, it has become urgent to develop multifunctional wound dressings that can combat infection and prompt wound healing simultaneously.					
36719417	0	21	theme	Polydopamine/Alginate	19:39	arg1	Hydrogel					41:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel	0:48	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	5	22	theme	bioactive	1146:1154	arg1	dressing					1156:1163	anti-infection bioactive dressing	1131:1163	anti-infection bioactive dressing	1131:1163	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	2	23	theme	composite	341:349	arg1	hydrogel					351:358	a polydopamine/alginate/nanoselenium composite hydrogel	304:358	a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds	304:408	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36719417	2	23	theme	composite	341:349	arg1	Alg-PDA-Se					361:370	Alg-PDA-Se	361:370	Alg-PDA-Se	361:370	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36719417	3	24	theme	low-dosage	532:541	arg1	nanoparticles					552:564	low-dosage selenium nanoparticles	532:564	low-dosage selenium nanoparticles (Se NPs)	532:573	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	24	theme	low-dosage	532:541	arg1	NPs					570:572	Se NPs	567:572	Se NPs	567:572	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	25	theme	composite	450:458	arg1	hydrogel					460:467	the composite hydrogel	446:467	the composite hydrogel	446:467	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	5	26	theme	composite	1077:1085	arg1	candidate					1117:1125	a potential candidate	1105:1125	a potential candidate for anti-infection bioactive dressing	1105:1163	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	5	26	theme	composite	1077:1085	arg1	hydrogel					1087:1094	the designed composite hydrogel	1064:1094	the designed composite hydrogel	1064:1094	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	4	27	dep	coli	967:970	arg1	coli					976:979	E. coli	973:979	E. coli	973:979	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	28	theme	near-infrared	487:499	arg1	properties					514:523	controllable near-infrared photothermal properties	474:523	controllable near-infrared photothermal properties	474:523	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	29	theme	multiple	715:722	arg1	cells					783:787	endothelial cells	771:787	endothelial cells	771:787	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	29	theme	multiple	715:722	arg1	fibroblasts					754:764	fibroblasts	754:764	fibroblasts	754:764	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	29	theme	multiple	715:722	arg1	cells					724:728	multiple cells	715:728	multiple cells	715:728	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	29	theme	multiple	715:722	arg1	macrophages					741:751	macrophages	741:751	macrophages	741:751	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	4	30	theme	temperature	834:844	arg1	combination					814:824	the combination	810:824	the combination of mild temperature with low-dosage Se NPs	810:867	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	5	31	theme	potential	1107:1115	arg1	candidate					1117:1125	a potential candidate	1105:1125	a potential candidate for anti-infection bioactive dressing	1105:1163	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	5	31	theme	potential	1107:1115	arg1	hydrogel					1087:1094	the designed composite hydrogel	1064:1094	the designed composite hydrogel	1064:1094	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	3	32	theme	pro-angiogenic	664:677	arg1	performances					679:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	33	theme	Se	567:568	arg1	nanoparticles					552:564	low-dosage selenium nanoparticles	532:564	low-dosage selenium nanoparticles (Se NPs)	532:573	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	33	theme	Se	567:568	arg1	NPs					570:572	Se NPs	567:572	Se NPs	567:572	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	4	34	with	combination	814:824	arg1	NPs					865:867	low-dosage Se NPs	851:867	low-dosage Se NPs	851:867	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	3	35	theme	selenium	543:550	arg1	nanoparticles					552:564	low-dosage selenium nanoparticles	532:564	low-dosage selenium nanoparticles (Se NPs)	532:573	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	35	theme	selenium	543:550	arg1	NPs					570:572	Se NPs	567:572	Se NPs	567:572	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	36	theme	pro-proliferative	626:642	arg1	performances					679:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	1	37	theme	wound	247:251	arg1	healing					253:259	wound healing	247:259	wound healing	247:259	In clinical practice, it has become urgent to develop multifunctional wound dressings that can combat infection and prompt wound healing simultaneously.					
36719417	3	38	theme	anti-inflammatory	607:623	arg1	performances					679:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances	607:690	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	3	39	theme	excellent	581:589	arg1	anti-oxidation					591:604	excellent anti-oxidation	581:604	excellent anti-oxidation	581:604	In particular, polydopamine endows the composite hydrogel with controllable near-infrared photothermal properties, while low-dosage selenium nanoparticles (Se NPs) offer excellent anti-oxidation, anti-inflammatory, pro-proliferative, pro-migration, and pro-angiogenic performances, which are verified by multiple cells, including macrophages, fibroblasts, and endothelial cells.					
36719417	0	40	theme	Infected	100:107	arg1	Healing					115:121	Infected Wound Healing	100:121	Infected Wound Healing	100:121	Mild Heat-Assisted Polydopamine/Alginate Hydrogel Containing Low-Dose Nanoselenium for Facilitating Infected Wound Healing.					
36719417	5	41	theme	anti-infection	1131:1144	arg1	dressing					1156:1163	anti-infection bioactive dressing	1131:1163	anti-infection bioactive dressing	1131:1163	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	5	42	theme	designed	1068:1075	arg1	candidate					1117:1125	a potential candidate	1105:1125	a potential candidate for anti-infection bioactive dressing	1105:1163	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	5	42	theme	designed	1068:1075	arg1	hydrogel					1087:1094	the designed composite hydrogel	1064:1094	the designed composite hydrogel	1064:1094	We anticipate that the designed composite hydrogel might be a potential candidate for anti-infection bioactive dressing.					
36719417	4	43	theme	synergistic	880:890	arg1	effect					892:897	a synergistic effect	878:897	a synergistic effect	878:897	More interestingly, the combination of mild temperature with low-dosage Se NPs produces a synergistic effect on combating both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and promoting the healing of bacteria-infected wounds in vivo.					
36719417	2	44	theme	wounds	403:408	arg1	treatment					381:389	the treatment	377:389	the treatment of infected wounds	377:408	In this study, we proposed a polydopamine/alginate/nanoselenium composite hydrogel (Alg-PDA-Se) for the treatment of infected wounds.					
36087478	0	0	theme	loaded	89:94	arg1	microcapsules					96:108	oregano essential oil loaded microcapsules	67:108	oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide	67:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	2	1	theme	encapsulation	515:527	arg1	yield					529:533	encapsulation yield	515:533	encapsulation yield	515:533	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	1	2	theme	oil	258:260	arg1	microcapsules					275:287	oregano essential oil (OEO) loaded microcapsules	240:287	oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2)	240:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	0	3	theme	oil	85:87	arg1	microcapsules					96:108	oregano essential oil loaded microcapsules	67:108	oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide	67:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	5	4	theme	damaged	934:940	arg1	structures					948:957	the damaged shell structures	930:957	the damaged shell structures	930:957	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	5	4	theme	damaged	934:940	arg1	advantageous					1012:1023	advantageous	1012:1023	advantageous	1012:1023	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	2	5	theme	loose	539:543	arg1	density					550:556	loose bulk density	539:556	loose bulk density	539:556	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	4	6	theme	UV	803:804	arg1	irradiation					806:816	UV irradiation	803:816	UV irradiation	803:816	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	3	7	theme	Fickian	712:718	arg1	diffusion					720:728	a classical Fickian diffusion	700:728	a classical Fickian diffusion	700:728	Microcapsules loaded TiO2 were more conducive to release after UV irradiation and the mechanism involved in the release process was followed a classical Fickian diffusion.					
36087478	0	8	theme	titanium	132:139	arg1	dioxide					141:147	chitosan-decorated titanium dioxide	113:147	chitosan-decorated titanium dioxide	113:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	5	9	theme	shell	942:946	arg1	structures					948:957	the damaged shell structures	930:957	the damaged shell structures	930:957	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	5	9	theme	shell	942:946	arg1	advantageous					1012:1023	advantageous	1012:1023	advantageous	1012:1023	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	6	10	theme	promising	1100:1108	arg1	strategy					1110:1117	a promising strategy	1098:1117	a promising strategy for controlling the release by UV irradiation according to the needs	1098:1186	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	6	10	theme	promising	1100:1108	arg1	TiO2					1068:1071	loading TiO2	1060:1071	loading TiO2 in core-shell system	1060:1092	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	0	11	theme	chitosan-decorated	113:130	arg1	dioxide					141:147	chitosan-decorated titanium dioxide	113:147	chitosan-decorated titanium dioxide	113:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	4	12	contain	had	749:751	arg2	stability					768:776	higher thermal stability	753:776	higher thermal stability	753:776	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	4	12	contain	had	749:751	arg1	microcapsules					735:747	The microcapsules	731:747	The microcapsules	731:747	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	6	13	from	TiO2	1068:1071	arg1	system					1087:1092	core-shell system	1076:1092	core-shell system	1076:1092	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	2	14	theme	bulk	545:548	arg1	density					550:556	loose bulk density	539:556	loose bulk density	539:556	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	1	15	theme	loaded	268:273	arg1	microcapsules					275:287	oregano essential oil (OEO) loaded microcapsules	240:287	oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2)	240:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	3	16	theme	classical	702:710	arg1	diffusion					720:728	a classical Fickian diffusion	700:728	a classical Fickian diffusion	700:728	Microcapsules loaded TiO2 were more conducive to release after UV irradiation and the mechanism involved in the release process was followed a classical Fickian diffusion.					
36087478	5	17	theme	XPS	914:916	arg1	analysis					893:900	the analysis	889:900	the analysis of FTIR and XPS	889:916	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	0	18	theme	release	26:32	arg1	characterization					34:49	immediate release characterization	16:49	immediate release characterization	16:49	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	5	19	theme	glycosidic	985:994	arg1	bonds					996:1000	glycosidic bonds	985:1000	glycosidic bonds	985:1000	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	1	20	theme	triggerable	196:206	arg1	system					208:213	a triggerable system	194:213	a triggerable system of core-shell structure	194:237	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	0	21	theme	immediate	16:24	arg1	characterization					34:49	immediate release characterization	16:49	immediate release characterization	16:49	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	2	22	mod	modification	459:470	arg3	surface					451:457	The surface modification	447:470	The surface modification of chitosan composite shells	447:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	2	22	mod	modification	459:470	arg1	shells					494:499	chitosan composite shells	475:499	chitosan composite shells	475:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	1	23	theme	immediate	384:392	arg1	abilities					412:420	their immediate triggered release abilities	378:420	their immediate triggered release abilities	378:420	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	4	24	theme	free	790:793	arg1	OEO					795:797	free OEO	790:797	free OEO	790:797	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	1	25	theme	chitosan-decorated	292:309	arg1	dioxide					320:326	chitosan-decorated titanium dioxide	292:326	chitosan-decorated titanium dioxide (TiO2)	292:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	25	theme	chitosan-decorated	292:309	arg1	TiO2					329:332	TiO2	329:332	TiO2	329:332	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	26	theme	triggered	394:402	arg1	abilities					412:420	their immediate triggered release abilities	378:420	their immediate triggered release abilities	378:420	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	5	27	theme	OEO	1044:1046	arg1	overflow					1032:1039	the overflow	1028:1039	the overflow of OEO	1028:1046	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	6	28	dep	the	1178:1180	arg1	needs					1182:1186	needs	1182:1186	needs	1182:1186	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	2	29	theme	shells	494:499	arg1	modification					459:470	The surface modification	447:470	The surface modification of chitosan composite shells	447:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	1	30	theme	titanium	311:318	arg1	dioxide					320:326	chitosan-decorated titanium dioxide	292:326	chitosan-decorated titanium dioxide (TiO2)	292:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	30	theme	titanium	311:318	arg1	TiO2					329:332	TiO2	329:332	TiO2	329:332	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	31	theme	release	404:410	arg1	abilities					412:420	their immediate triggered release abilities	378:420	their immediate triggered release abilities	378:420	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	2	32	theme	surface	451:457	arg1	modification					459:470	The surface modification	447:470	The surface modification of chitosan composite shells	447:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	1	33	theme	core-shell	218:227	arg1	structure					229:237	core-shell structure	218:237	core-shell structure	218:237	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	2	34	theme	composite	484:492	arg1	shells					494:499	chitosan composite shells	475:499	chitosan composite shells	475:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	3	35	theme	release	671:677	arg1	process					679:685	the release process	667:685	the release process	667:685	Microcapsules loaded TiO2 were more conducive to release after UV irradiation and the mechanism involved in the release process was followed a classical Fickian diffusion.					
36087478	4	36	theme	higher	753:758	arg1	stability					768:776	higher thermal stability	753:776	higher thermal stability	753:776	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	0	37	theme	UV	54:55	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication	0:10	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	0	37	theme	UV	54:55	arg1	characterization					34:49	immediate release characterization	16:49	immediate release characterization	16:49	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	2	38	theme	chitosan	475:482	arg1	shells					494:499	chitosan composite shells	475:499	chitosan composite shells	475:499	The surface modification of chitosan composite shells could improve encapsulation yield and loose bulk density.					
36087478	3	39	theme	UV	622:623	arg1	irradiation					625:635	UV irradiation	622:635	UV irradiation	622:635	Microcapsules loaded TiO2 were more conducive to release after UV irradiation and the mechanism involved in the release process was followed a classical Fickian diffusion.					
36087478	6	40	theme	UV	1150:1151	arg1	irradiation					1153:1163	UV irradiation	1150:1163	UV irradiation	1150:1163	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	1	41	theme	UV-mediated	425:435	arg1	triggers					437:444	UV-mediated triggers	425:444	UV-mediated triggers	425:444	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	4	42	theme	thermal	830:836	arg1	stability					838:846	the thermal stability	826:846	the thermal stability of microcapsules with TiO2	826:873	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	4	43	theme	microcapsules	851:863	arg1	stability					838:846	the thermal stability	826:846	the thermal stability of microcapsules with TiO2	826:873	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	1	44	theme	structure	229:237	arg1	system					208:213	a triggerable system	194:213	a triggerable system of core-shell structure	194:237	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	4	45	theme	thermal	760:766	arg1	stability					768:776	higher thermal stability	753:776	higher thermal stability	753:776	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	0	46	theme	essential	75:83	arg1	microcapsules					96:108	oregano essential oil loaded microcapsules	67:108	oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide	67:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	6	47	theme	loading	1060:1066	arg1	strategy					1110:1117	a promising strategy	1098:1117	a promising strategy for controlling the release by UV irradiation according to the needs	1098:1186	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	6	47	theme	loading	1060:1066	arg1	TiO2					1068:1071	loading TiO2	1060:1071	loading TiO2 in core-shell system	1060:1092	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	6	48	theme	core-shell	1076:1085	arg1	system					1087:1092	core-shell system	1076:1092	core-shell system	1076:1092	Therefore, loading TiO2 in core-shell system was a promising strategy for controlling the release by UV irradiation according to the needs.					
36087478	1	49	theme	present	157:163	arg1	study					165:169	the present study	153:169	the present study	153:169	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	5	50	theme	FTIR	905:908	arg1	analysis					893:900	the analysis	889:900	the analysis of FTIR and XPS	889:916	Furthermore, the analysis of FTIR and XPS showed that the damaged shell structures were observed, especially glycosidic bonds, and were advantageous to the overflow of OEO.					
36087478	1	51	theme	oregano	240:246	arg1	OEO					263:265	OEO	263:265	OEO	263:265	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	51	theme	oregano	240:246	arg1	oil					258:260	oregano essential oil	240:260	oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2)	240:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	0	52	theme	oregano	67:73	arg1	microcapsules					96:108	oregano essential oil loaded microcapsules	67:108	oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide	67:147	Fabrication and immediate release characterization of UV responded oregano essential oil loaded microcapsules by chitosan-decorated titanium dioxide.					
36087478	4	53	with	microcapsules	851:863	arg1	TiO2					870:873	TiO2	870:873	TiO2	870:873	The microcapsules had higher thermal stability compared to free OEO but UV irradiation reduced the thermal stability of microcapsules with TiO2.					
36087478	1	54	theme	essential	248:256	arg1	OEO					263:265	OEO	263:265	OEO	263:265	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36087478	1	54	theme	essential	248:256	arg1	oil					258:260	oregano essential oil	240:260	oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2)	240:333	In the present study, in order to establish a triggerable system of core-shell structure, oregano essential oil (OEO) loaded microcapsules by chitosan-decorated titanium dioxide (TiO2) were prepared and characterized to explore their immediate triggered release abilities by UV-mediated triggers.					
36592852	0	0	theme	regenerative	83:94	arg1	potential					96:104	promising regenerative potential	73:104	promising regenerative potential	73:104	Biocomposite films based on chitosan and cerium oxide nanoparticles with promising regenerative potential.					
36592852	6	1	theme	CeONPs	915:920	arg1	incorporation					898:910	The incorporation	894:910	The incorporation of CeONPs into the salt form of CS	894:945	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	8	2	theme	In	1260:1261	arg1	culture					1269:1275	In vitro culture	1260:1275	In vitro culture of MSCs	1260:1283	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	3	3	theme	citrate-stabilized	510:527	arg1	CeONPs					529:534	The citrate-stabilized CeONPs	506:534	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV)	506:573	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	3	3	theme	citrate-stabilized	510:527	arg1	precoated					580:588	precoated	580:588	precoated	580:588	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	6	4	theme	film	987:990	arg1	stiffness					961:969	the stiffness	957:969	the stiffness of the CS-CeONP film	957:990	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	0	5	theme	promising	73:81	arg1	potential					96:104	promising regenerative potential	73:104	promising regenerative potential	73:104	Biocomposite films based on chitosan and cerium oxide nanoparticles with promising regenerative potential.					
36592852	1	6	contain	have	141:144	arg1	materials					131:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	1	6	contain	have	141:144	arg2	potential					152:160	great potential	146:160	great potential	146:160	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	3	7	with	CeONPs	529:534	arg1	-25.0 mV					565:572	-25.0 mV	565:572	-25.0 mV	565:572	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	3	7	with	CeONPs	529:534	arg1	ζ-potential					552:562	a negative ζ-potential	541:562	a negative ζ-potential (-25.0 mV)	541:573	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	6	8	theme	CS-CeONP	978:985	arg1	film					987:990	the CS-CeONP film	974:990	the CS-CeONP film	974:990	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	7	9	theme	redox	1146:1150	arg1	activity					1152:1159	The redox activity	1142:1159	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film	1142:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	7	9	theme	redox	1146:1150	arg1	Ce3+					1169:1172	Ce4+ ⇌ Ce3+	1162:1172	Ce4+ ⇌ Ce3+	1162:1172	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	4	10	theme	basic	767:771	arg1	forms					773:777	basic forms	767:777	basic forms	767:777	The composite CS-CeONP films were prepared in the salt and basic forms using a dry-cast process.					
36592852	3	11	theme	composite	688:696	arg1	solution					698:705	the composite solution	684:705	the composite solution	684:705	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	6	12	theme	yield	1129:1133	arg1	point					1135:1139	the yield point	1125:1139	the yield point	1125:1139	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	6	13	theme	threefold	1074:1082	arg1	decrease					1084:1091	a two- to threefold decrease	1064:1091	a two- to threefold decrease in both the Young's modulus and the yield point	1064:1139	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	4	14	dep	salt	758:761	arg1	the					754:756	the	754:756	the	754:756	The composite CS-CeONP films were prepared in the salt and basic forms using a dry-cast process.					
36592852	3	15	theme	negative	543:550	arg1	-25.0 mV					565:572	-25.0 mV	565:572	-25.0 mV	565:572	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	3	15	theme	negative	543:550	arg1	ζ-potential					552:562	a negative ζ-potential	541:562	a negative ζ-potential (-25.0 mV)	541:573	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	5	16	theme	uniform	862:868	arg1	distribution					870:881	a uniform distribution	860:881	a uniform distribution of CeONPs	860:891	The films obtained in both forms were characterized by a uniform distribution of CeONPs.					
36592852	1	17	theme	tissue-engineered	184:200	arg1	scaffolds					202:210	tissue-engineered scaffolds	184:210	tissue-engineered scaffolds	184:210	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	0	18	theme	cerium	41:46	arg1	oxide					48:52	cerium oxide	41:52	cerium oxide	41:52	Biocomposite films based on chitosan and cerium oxide nanoparticles with promising regenerative potential.					
36592852	8	19	theme	regenerative	1395:1406	arg1	potential					1408:1416	its substantial regenerative potential	1379:1416	its substantial regenerative potential	1379:1416	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	1	20	theme	scaffolds	202:210	arg1	development					169:179	the development	165:179	the development of tissue-engineered scaffolds	165:210	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	2	21	theme	multipotent	463:473	arg1	MSCs					499:502	MSCs	499:502	MSCs	499:502	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	21	theme	multipotent	463:473	arg1	cells					492:496	multipotent mesenchymal stem cells	463:496	multipotent mesenchymal stem cells (MSCs)	463:503	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	7	22	theme	Ce4+	1162:1165	arg1	activity					1152:1159	The redox activity	1142:1159	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film	1142:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	7	22	theme	Ce4+	1162:1165	arg1	Ce3+					1169:1172	Ce4+ ⇌ Ce3+	1162:1172	Ce4+ ⇌ Ce3+	1162:1172	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	2	23	theme	cerium	351:356	arg1	CeONPs					379:384	CeONPs	379:384	CeONPs	379:384	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	23	theme	cerium	351:356	arg1	nanoparticles					364:376	cerium oxide nanoparticles	351:376	cerium oxide nanoparticles (CeONPs)	351:385	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	24	theme	chitosan	412:419	arg1	film					426:429	a chitosan (CS) film	410:429	a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs)	410:503	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	0	25	theme	Biocomposite	0:11	arg1	films					13:17	Biocomposite films	0:17	Biocomposite films based on chitosan and cerium oxide	0:52	Biocomposite films based on chitosan and cerium oxide nanoparticles with promising regenerative potential.					
36592852	8	26	dep	in	1346:1347	arg1	vivo					1349:1352	vivo	1349:1352	vivo	1349:1352	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	3	27	with	precoated	580:588	arg1	CS					595:596	CS	595:596	CS	595:596	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	1	28	theme	Polymeric	107:115	arg1	materials					131:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	6	29	theme	film	1032:1035	arg1	conversion					1014:1023	the subsequent conversion	999:1023	the subsequent conversion of the film to the basic form	999:1053	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	8	30	theme	MSCs	1280:1283	arg1	culture					1269:1275	In vitro culture	1260:1275	In vitro culture of MSCs	1260:1283	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	1	31	theme	nanocomposite	117:129	arg1	materials					131:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials	107:139	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	7	32	theme	thermal	1229:1235	arg1	degradation					1247:1257	thermal oxidative degradation	1229:1257	thermal oxidative degradation	1229:1257	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	6	33	theme	CS	944:945	arg1	form					936:939	the salt form	927:939	the salt form of CS	927:945	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	8	34	dep	In	1260:1261	arg1	vitro					1263:1267	vitro	1263:1267	vitro	1263:1267	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	2	35	theme	cells	492:496	arg1	proliferation					446:458	the proliferation	442:458	the proliferation of multipotent mesenchymal stem cells (MSCs)	442:503	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	8	36	theme	substantial	1383:1393	arg1	potential					1408:1416	its substantial regenerative potential	1379:1416	its substantial regenerative potential	1379:1416	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	2	37	theme	stem	487:490	arg1	MSCs					499:502	MSCs	499:502	MSCs	499:502	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	37	theme	stem	487:490	arg1	cells					492:496	multipotent mesenchymal stem cells	463:496	multipotent mesenchymal stem cells (MSCs)	463:503	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	8	38	contain	has	1315:1317	arg1	film					1310:1313	the CS-CeONP film	1297:1313	the CS-CeONP film	1297:1313	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	8	38	contain	has	1315:1317	arg2	biocompatibility					1324:1339	good biocompatibility	1319:1339	good biocompatibility	1319:1339	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	7	39	from	activity	1152:1159	arg1	film					1207:1210	the CS-CeONP film	1194:1210	the CS-CeONP film	1194:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	4	40	theme	CS-CeONP	722:729	arg1	films					731:735	The composite CS-CeONP films	708:735	The composite CS-CeONP films	708:735	The composite CS-CeONP films were prepared in the salt and basic forms using a dry-cast process.					
36592852	2	41	theme	mesenchymal	475:485	arg1	MSCs					499:502	MSCs	499:502	MSCs	499:502	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	41	theme	mesenchymal	475:485	arg1	cells					492:496	multipotent mesenchymal stem cells	463:496	multipotent mesenchymal stem cells (MSCs)	463:503	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	6	42	theme	salt	931:934	arg1	form					936:939	the salt form	927:939	the salt form of CS	927:945	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	1	43	dep	cell	297:300	arg1	differentiation					320:334	differentiation	320:334	differentiation	320:334	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	1	43	dep	cell	297:300	arg1	proliferation					302:314	proliferation	302:314	proliferation	302:314	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	8	44	theme	good	1319:1322	arg1	biocompatibility					1324:1339	good biocompatibility	1319:1339	good biocompatibility	1319:1339	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	7	45	theme	CS-CeONP	1198:1205	arg1	film					1207:1210	the CS-CeONP film	1194:1210	the CS-CeONP film	1194:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	4	46	theme	composite	712:720	arg1	films					731:735	The composite CS-CeONP films	708:735	The composite CS-CeONP films	708:735	The composite CS-CeONP films were prepared in the salt and basic forms using a dry-cast process.					
36592852	7	47	theme	oxide	1185:1189	arg1	activity					1152:1159	The redox activity	1142:1159	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film	1142:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	7	47	theme	oxide	1185:1189	arg1	Ce3+					1169:1172	Ce4+ ⇌ Ce3+	1162:1172	Ce4+ ⇌ Ce3+	1162:1172	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	4	48	theme	dry-cast	787:794	arg1	process					796:802	a dry-cast process	785:802	a dry-cast process	785:802	The composite CS-CeONP films were prepared in the salt and basic forms using a dry-cast process.					
36592852	1	49	dep	structure	236:244	arg1	the					232:234	the	232:234	the	232:234	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	1	50	theme	great	146:150	arg1	potential					152:160	great potential	146:160	great potential	146:160	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	6	51	theme	Young	1105:1109	arg1	modulus					1113:1119	the Young's modulus	1101:1119	the Young's modulus	1101:1119	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	6	52	theme	subsequent	1003:1012	arg1	conversion					1014:1023	the subsequent conversion	999:1023	the subsequent conversion of the film to the basic form	999:1053	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	6	53	dep	threefold	1074:1082	arg1	to					1071:1072	to	1071:1072	to	1071:1072	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	2	54	theme	oxide	358:362	arg1	CeONPs					379:384	CeONPs	379:384	CeONPs	379:384	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	2	54	theme	oxide	358:362	arg1	nanoparticles					364:376	cerium oxide nanoparticles	351:376	cerium oxide nanoparticles (CeONPs)	351:385	In this work, cerium oxide nanoparticles (CeONPs) were incorporated into a chitosan (CS) film to improve the proliferation of multipotent mesenchymal stem cells (MSCs).					
36592852	7	55	theme	oxidative	1237:1245	arg1	degradation					1247:1257	thermal oxidative degradation	1229:1257	thermal oxidative degradation	1229:1257	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	7	56	theme	⇌	1167:1167	arg1	activity					1152:1159	The redox activity	1142:1159	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film	1142:1210	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	7	56	theme	⇌	1167:1167	arg1	Ce3+					1169:1172	Ce4+ ⇌ Ce3+	1162:1172	Ce4+ ⇌ Ce3+	1162:1172	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	8	57	theme	CS-CeONP	1301:1308	arg1	film					1310:1313	the CS-CeONP film	1297:1313	the CS-CeONP film	1297:1313	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	3	58	theme	charged	619:625	arg1	particles					627:635	positively charged particles	608:635	positively charged particles (+20.3 mV)	608:646	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	3	58	theme	charged	619:625	arg1	+20.3 mV					638:645	+20.3 mV	638:645	+20.3 mV	638:645	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	7	59	theme	cerium	1178:1183	arg1	oxide					1185:1189	cerium oxide	1178:1189	cerium oxide	1178:1189	The redox activity (Ce4+ ⇌ Ce3+) of cerium oxide in the CS-CeONP film was confirmed by thermal oxidative degradation.					
36592852	6	60	theme	basic	1044:1048	arg1	form					1050:1053	the basic form	1040:1053	the basic form	1040:1053	The incorporation of CeONPs into the salt form of CS increased the stiffness of the CS-CeONP film, while the subsequent conversion of the film to the basic form provided a two- to threefold decrease in both the Young's modulus and the yield point.					
36592852	1	61	theme	polymeric	264:272	arg1	materials					274:282	polymeric materials	264:282	polymeric materials	264:282	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	3	62	from	aggregation	669:679	arg1	solution					698:705	the composite solution	684:705	the composite solution	684:705	The citrate-stabilized CeONPs with a negative ζ-potential (-25.0 mV) were precoated with CS to obtain positively charged particles (+20.3 mV) and to prevent their aggregation in the composite solution.					
36592852	8	63	theme	in	1346:1347	arg1	experiments					1354:1364	in vivo experiments	1346:1364	in vivo experiments	1346:1364	In vitro culture of MSCs showed that the CS-CeONP film has good biocompatibility, and in vivo experiments demonstrated its substantial regenerative potential.					
36592852	5	64	theme	CeONPs	886:891	arg1	distribution					870:881	a uniform distribution	860:881	a uniform distribution of CeONPs	860:891	The films obtained in both forms were characterized by a uniform distribution of CeONPs.					
36592852	1	65	theme	materials	274:282	arg1	properties					250:259	properties	250:259	properties	250:259	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36592852	1	65	theme	materials	274:282	arg1	structure					236:244	structure	236:244	structure	236:244	Polymeric nanocomposite materials have great potential in the development of tissue-engineered scaffolds because they affect the structure and properties of polymeric materials and regulate cell proliferation and differentiation.					
36469414	5	0	theme	bone	800:803	arg1	microenvironment					814:829	bone ECM-like microenvironment	800:829	bone ECM-like microenvironment	800:829	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	7	1	theme	bone	1279:1282	arg1	regeneration					1284:1295	bone regeneration	1279:1295	bone regeneration	1279:1295	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	0	2	with	Scaffold	26:33	arg1	Microenvironment					76:91	Viscoelastic Microenvironment	63:91	Viscoelastic Microenvironment	63:91	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	0	2	with	Scaffold	26:33	arg1	Crystalline					47:57	Liquid Crystalline	40:57	Liquid Crystalline	40:57	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	1	3	theme	effective	156:164	arg1	strategy					178:185	an effective therapeutic strategy	153:185	an effective therapeutic strategy for personalized bone repair	153:214	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	7	4	theme	ECM-like	1100:1107	arg1	state					1128:1132	bone ECM-like liquid crystalline state	1095:1132	bone ECM-like liquid crystalline state	1095:1132	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	4	5	theme	ECM-like	608:615	arg1	microenvironment					617:632	a bone ECM-like microenvironment	601:632	a bone ECM-like microenvironment	601:632	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	5	6	theme	ECM-like	805:812	arg1	microenvironment					814:829	bone ECM-like microenvironment	800:829	bone ECM-like microenvironment	800:829	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	1	7	theme	therapeutic	166:176	arg1	strategy					178:185	an effective therapeutic strategy	153:185	an effective therapeutic strategy for personalized bone repair	153:214	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	4	8	theme	bone	603:606	arg1	microenvironment					617:632	a bone ECM-like microenvironment	601:632	a bone ECM-like microenvironment	601:632	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	7	9	theme	robust	1175:1180	arg1	scaffold					1187:1194	the robust PLLA scaffold	1171:1194	the robust PLLA scaffold	1171:1194	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	0	10	theme	Bone	97:100	arg1	Regeneration					102:113	Bone Regeneration	97:113	Bone Regeneration	97:113	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	7	11	theme	PLLA	1182:1185	arg1	scaffold					1187:1194	the robust PLLA scaffold	1171:1194	the robust PLLA scaffold	1171:1194	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	2	12	theme	mechanical	371:380	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	12	theme	mechanical	371:380	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	12	theme	mechanical	371:380	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	9	13	theme	excellent	1552:1560	arg1	properties					1573:1582	excellent mechanical properties	1552:1582	excellent mechanical properties	1552:1582	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	7	14	with	hydrogel	1081:1088	arg1	state					1128:1132	bone ECM-like liquid crystalline state	1095:1132	bone ECM-like liquid crystalline state	1095:1132	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	7	14	with	hydrogel	1081:1088	arg1	viscoelasticity					1138:1152	viscoelasticity	1138:1152	viscoelasticity	1138:1152	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	5	15	theme	bionic	764:769	arg1	scaffold					771:778	a bionic scaffold	762:778	a bionic scaffold	762:778	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	9	16	with	scaffold	1503:1510	arg1	microenvironment					1531:1546	bone ECM-like microenvironment	1517:1546	bone ECM-like microenvironment	1517:1546	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	9	16	with	scaffold	1503:1510	arg1	properties					1573:1582	excellent mechanical properties	1552:1582	excellent mechanical properties	1552:1582	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	7	17	dep	build	1199:1203	arg1	promoting					1269:1277	promoting	1269:1277	highly promoting bone regeneration	1262:1295	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	8	18	theme	angiogenic	1325:1334	arg1	factor					1336:1341	an angiogenic factor	1322:1341	an angiogenic factor	1322:1341	Moreover, deferoxamine, an angiogenic factor, was encapsulated in the composite hydrogel and sustainably released, playing a long-term role in angiogenesis and thereby further promoting osteogenesis.					
36469414	8	18	theme	angiogenic	1325:1334	arg1	deferoxamine					1308:1319	deferoxamine	1308:1319	deferoxamine	1308:1319	Moreover, deferoxamine, an angiogenic factor, was encapsulated in the composite hydrogel and sustainably released, playing a long-term role in angiogenesis and thereby further promoting osteogenesis.					
36469414	8	19	theme	long-term	1423:1431	arg1	role					1433:1436	a long-term role	1421:1436	a long-term role	1421:1436	Moreover, deferoxamine, an angiogenic factor, was encapsulated in the composite hydrogel and sustainably released, playing a long-term role in angiogenesis and thereby further promoting osteogenesis.					
36469414	4	20	theme	huge	696:699	arg1	challenge					701:709	a huge challenge	694:709	a huge challenge	694:709	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	3	21	theme	ideal	412:416	arg1	microenvironment					429:444	the most ideal osteogenic microenvironment	403:444	the most ideal osteogenic microenvironment	403:444	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	7	22	theme	bone	1209:1212	arg1	microenvironment					1223:1238	the bone ECM-like microenvironment	1205:1238	the bone ECM-like microenvironment	1205:1238	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	9	23	theme	effective	1608:1616	arg1	implantation					1618:1629	an effective implantation	1605:1629	an effective implantation for bone repair	1605:1645	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	9	23	theme	effective	1608:1616	arg1	scaffold					1503:1510	This scaffold	1498:1510	This scaffold with bone ECM-like microenvironment and excellent mechanical properties	1498:1582	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	2	24	theme	engineering	266:276	arg1	success					243:249	the success	239:249	the success of bone tissue engineering	239:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	9	25	theme	ECM-like	1522:1529	arg1	microenvironment					1531:1546	bone ECM-like microenvironment	1517:1546	bone ECM-like microenvironment	1517:1546	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	0	26	theme	ECM-like	5:12	arg1	Scaffold					26:33	Bone ECM-like 3D Printing Scaffold	0:33	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.	0:114	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	7	27	theme	bone	1095:1098	arg1	state					1128:1132	bone ECM-like liquid crystalline state	1095:1132	bone ECM-like liquid crystalline state	1095:1132	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	2	28	theme	appropriate	310:320	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	28	theme	appropriate	310:320	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	28	theme	appropriate	310:320	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	7	29	theme	3D	1243:1244	arg1	structure					1246:1254	3D structure	1243:1254	3D structure	1243:1254	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	1	30	theme	personalized	191:202	arg1	repair					209:214	personalized bone repair	191:214	personalized bone repair	191:214	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	0	31	theme	Bone	0:3	arg1	Scaffold					26:33	Bone ECM-like 3D Printing Scaffold	0:33	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.	0:114	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	6	32	dep	printing	880:887	arg1	scaffold					914:921	a poly(l-lactide) (PLLA) scaffold	889:921	3D printing a poly(l-lactide) (PLLA) scaffold	877:921	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	1	33	theme	bone	204:207	arg1	repair					209:214	personalized bone repair	191:214	personalized bone repair	191:214	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	0	34	theme	Printing	17:24	arg1	Scaffold					26:33	Bone ECM-like 3D Printing Scaffold	0:33	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.	0:114	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	8	35	theme	composite	1368:1376	arg1	hydrogel					1378:1385	the composite hydrogel	1364:1385	the composite hydrogel	1364:1385	Moreover, deferoxamine, an angiogenic factor, was encapsulated in the composite hydrogel and sustainably released, playing a long-term role in angiogenesis and thereby further promoting osteogenesis.					
36469414	9	36	theme	bone	1517:1520	arg1	microenvironment					1531:1546	bone ECM-like microenvironment	1517:1546	bone ECM-like microenvironment	1517:1546	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	9	37	theme	mechanical	1562:1571	arg1	properties					1573:1582	excellent mechanical properties	1552:1582	excellent mechanical properties	1552:1582	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	3	38	theme	extracellular	486:498	arg1	ECM					508:510	ECM	508:510	ECM	508:510	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	3	38	theme	extracellular	486:498	arg1	matrix					500:505	natural bone extracellular matrix	473:505	natural bone extracellular matrix (ECM)	473:511	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	0	39	theme	3D	14:15	arg1	Scaffold					26:33	Bone ECM-like 3D Printing Scaffold	0:33	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.	0:114	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	5	40	theme	facile	733:738	arg1	approach					740:747	a facile approach	731:747	a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties	731:862	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	2	41	theme	excellent	361:369	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	41	theme	excellent	361:369	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	41	theme	excellent	361:369	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	9	42	theme	bone	1635:1638	arg1	repair					1640:1645	bone repair	1635:1645	bone repair	1635:1645	This scaffold with bone ECM-like microenvironment and excellent mechanical properties can be considered as an effective implantation for bone repair.					
36469414	4	43	theme	outstanding	657:667	arg1	properties					680:689	outstanding mechanical properties	657:689	outstanding mechanical properties	657:689	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	3	44	theme	osteogenic	418:427	arg1	microenvironment					429:444	the most ideal osteogenic microenvironment	403:444	the most ideal osteogenic microenvironment	403:444	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	6	45	theme	whiskers	1009:1016	arg1	self-assembly					985:997	layer-by-layer electrostatic self-assembly	956:997	layer-by-layer electrostatic self-assembly of chitin whiskers	956:1016	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	7	46	theme	crystalline	1116:1126	arg1	state					1128:1132	bone ECM-like liquid crystalline state	1095:1132	bone ECM-like liquid crystalline state	1095:1132	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	8	47	dep	playing	1413:1419	arg1	promoting					1474:1482	promoting	1474:1482	promoting osteogenesis	1474:1495	Moreover, deferoxamine, an angiogenic factor, was encapsulated in the composite hydrogel and sustainably released, playing a long-term role in angiogenesis and thereby further promoting osteogenesis.					
36469414	3	48	theme	natural	473:479	arg1	ECM					508:510	ECM	508:510	ECM	508:510	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	3	48	theme	natural	473:479	arg1	matrix					500:505	natural bone extracellular matrix	473:505	natural bone extracellular matrix (ECM)	473:511	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	7	49	theme	ECM-like	1214:1221	arg1	microenvironment					1223:1238	the bone ECM-like microenvironment	1205:1238	the bone ECM-like microenvironment	1205:1238	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	6	50	theme	chitin	1002:1007	arg1	whiskers					1009:1016	chitin whiskers	1002:1016	chitin whiskers	1002:1016	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	4	51	with	structure	642:650	arg1	properties					680:689	outstanding mechanical properties	657:689	outstanding mechanical properties	657:689	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	7	52	theme	composite	1071:1079	arg1	hydrogel					1081:1088	chitin whisker/chitosan composite hydrogel	1047:1088	chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity	1047:1152	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	3	53	theme	bone	481:484	arg1	ECM					508:510	ECM	508:510	ECM	508:510	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	3	53	theme	bone	481:484	arg1	matrix					500:505	natural bone extracellular matrix	473:505	natural bone extracellular matrix (ECM)	473:511	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	3	54	theme	most	407:410	arg1	microenvironment					429:444	the most ideal osteogenic microenvironment	403:444	the most ideal osteogenic microenvironment	403:444	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	5	55	theme	mechanical	842:851	arg1	properties					853:862	robust mechanical properties	835:862	robust mechanical properties	835:862	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	7	56	theme	hydrogel	1081:1088	arg1	kind					1039:1042	a kind	1037:1042	a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity	1037:1152	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	0	57	theme	Liquid	40:45	arg1	Crystalline					47:57	Liquid Crystalline	40:57	Liquid Crystalline	40:57	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	7	58	theme	liquid	1109:1114	arg1	state					1128:1132	bone ECM-like liquid crystalline state	1095:1132	bone ECM-like liquid crystalline state	1095:1132	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	6	59	theme	poly	891:894	arg1	scaffold					914:921	a poly(l-lactide) (PLLA) scaffold	889:921	3D printing a poly(l-lactide) (PLLA) scaffold	877:921	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	2	60	theme	key	224:226	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	60	theme	key	224:226	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	60	theme	key	224:226	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	7	61	theme	chitin	1047:1052	arg1	hydrogel					1081:1088	chitin whisker/chitosan composite hydrogel	1047:1088	chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity	1047:1152	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	1	62	theme	3D	129:130	arg1	scaffold					141:148	a 3D printing scaffold	127:148	a 3D printing scaffold	127:148	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	6	63	theme	electrostatic	971:983	arg1	self-assembly					985:997	layer-by-layer electrostatic self-assembly	956:997	layer-by-layer electrostatic self-assembly of chitin whiskers	956:1016	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	2	64	theme	tissue	259:264	arg1	engineering					266:276	bone tissue engineering	254:276	bone tissue engineering	254:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	7	65	theme	whisker/chitosan	1054:1069	arg1	hydrogel					1081:1088	chitin whisker/chitosan composite hydrogel	1047:1088	chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity	1047:1152	More importantly, a kind of chitin whisker/chitosan composite hydrogel with bone ECM-like liquid crystalline state and viscoelasticity was infused into the robust PLLA scaffold to build the bone ECM-like microenvironment in 3D structure, thus highly promoting bone regeneration.					
36469414	1	66	theme	printing	132:139	arg1	scaffold					141:148	a 3D printing scaffold	127:148	a 3D printing scaffold	127:148	Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair.					
36469414	4	67	theme	3D	639:640	arg1	structure					642:650	a 3D structure	637:650	a 3D structure with outstanding mechanical properties	637:689	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	3	68	theme	viscoelastic	552:563	arg1	characteristics					565:579	liquid crystalline and viscoelastic characteristics	529:579	liquid crystalline and viscoelastic characteristics	529:579	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	2	69	theme	bone	254:257	arg1	engineering					266:276	bone tissue engineering	254:276	bone tissue engineering	254:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	70	theme	bone	322:325	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	70	theme	bone	322:325	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	70	theme	bone	322:325	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	71	theme	regeneration	327:338	arg1	microenvironment					340:355	an appropriate bone regeneration microenvironment	307:355	an appropriate bone regeneration microenvironment	307:355	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	71	theme	regeneration	327:338	arg1	properties					382:391	excellent mechanical properties	361:391	excellent mechanical properties	361:391	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	2	71	theme	regeneration	327:338	arg1	factor					228:233	the key factor	220:233	the key factor for the success of bone tissue engineering	220:276	As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent mechanical properties.					
36469414	0	72	theme	Viscoelastic	63:74	arg1	Microenvironment					76:91	Viscoelastic Microenvironment	63:91	Viscoelastic Microenvironment	63:91	Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration.					
36469414	6	73	theme	3D	877:878	arg1	printing					880:887	3D printing	877:887	3D printing a poly(l-lactide) (PLLA) scaffold	877:921	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	4	74	theme	mechanical	669:678	arg1	properties					680:689	outstanding mechanical properties	657:689	outstanding mechanical properties	657:689	However, mimicking a bone ECM-like microenvironment in a 3D structure with outstanding mechanical properties is a huge challenge.					
36469414	3	75	theme	liquid	529:534	arg1	characteristics					565:579	liquid crystalline and viscoelastic characteristics	529:579	liquid crystalline and viscoelastic characteristics	529:579	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36469414	5	76	theme	robust	835:840	arg1	properties					853:862	robust mechanical properties	835:862	robust mechanical properties	835:862	Herein, we develop a facile approach to fabricate a bionic scaffold perfectly combining bone ECM-like microenvironment and robust mechanical properties.					
36469414	6	77	theme	layer-by-layer	956:969	arg1	self-assembly					985:997	layer-by-layer electrostatic self-assembly	956:997	layer-by-layer electrostatic self-assembly of chitin whiskers	956:1016	Creatively, 3D printing a poly(l-lactide) (PLLA) scaffold was effectively strengthened via layer-by-layer electrostatic self-assembly of chitin whiskers.					
36469414	3	78	theme	crystalline	536:546	arg1	characteristics					565:579	liquid crystalline and viscoelastic characteristics	529:579	liquid crystalline and viscoelastic characteristics	529:579	In fact, the most ideal osteogenic microenvironment is undoubtedly provided by natural bone extracellular matrix (ECM), which exhibits liquid crystalline and viscoelastic characteristics.					
36444040	2	0	theme	high-throughput	472:486	arg1	sequencing					488:497	high-throughput sequencing	472:497	high-throughput sequencing	472:497	In this study, the antidiabetic effect and mechanism of RK are investigated by serum metabolomics and high-throughput sequencing.					
36444040	1	1	theme	functional	324:333	arg1	component					335:343	the core functional component	315:343	the core functional component	315:343	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	1	2	theme	Crude	157:161	arg1	polysaccharides					163:177	Crude polysaccharides	157:177	Crude polysaccharides extracted from red kidney bean (RK)	157:213	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	4	3	from	symptoms	674:681	arg1	rats					740:743	STZ-induced diabetic rats	719:743	STZ-induced diabetic rats	719:743	Our data indicated that RK relieved the symptoms of hyperglycemia, hyperlipidemia in STZ-induced diabetic rats.					
36444040	6	4	dep	found	1010:1014	arg1	identified					1056:1065	identified	1056:1065	found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK	1010:1107	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	0	5	theme	diabetic	92:99	arg1	rats					101:104	type 2 diabetic rats	85:104	type 2 diabetic rats	85:104	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	7	6	theme	present	1114:1120	arg1	studies					1122:1128	Our present studies	1110:1128	Our present studies	1110:1128	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	1	7	theme	diabetic	267:274	arg1	mice					276:279	type 2 diabetic mice	260:279	type 2 diabetic mice	260:279	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	0	8	theme	gut	110:112	arg1	microbiota					114:123	gut microbiota	110:123	gut microbiota	110:123	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	0	9	from	hyperglycemia	49:61	arg1	rats					101:104	type 2 diabetic rats	85:104	type 2 diabetic rats	85:104	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	6	10	theme	biofunctional	1079:1091	arg1	component					1093:1101	the core biofunctional component	1070:1101	the core biofunctional component in RK	1070:1107	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	3	11	theme	key	517:519	arg1	component					521:529	the key component	513:529	the key component	513:529	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	5	12	theme	metabolic	771:779	arg1	disturbance					781:791	the metabolic disturbance	767:791	the metabolic disturbance	767:791	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	7	13	theme	type	1203:1206	arg1	individuals					1219:1229	type 2 diabetic individuals	1203:1229	type 2 diabetic individuals	1203:1229	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	5	14	theme	Blautia	990:996	arg1	genera					929:934	key genera	925:934	key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia	925:996	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	6	15	theme	core	1074:1077	arg1	component					1093:1101	the core biofunctional component	1070:1101	the core biofunctional component in RK	1070:1107	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	7	16	theme	dietary	1180:1186	arg1	RKP					1152:1154	RKP	1152:1154	RKP	1152:1154	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	7	16	theme	dietary	1180:1186	arg1	supplement					1188:1197	potential effective dietary supplement	1160:1197	potential effective dietary supplement for type 2 diabetic individuals	1160:1229	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	0	17	from	bean	32:35	arg1	Polysaccharides					0:14	Polysaccharides	0:14	Polysaccharides from red kidney bean	0:35	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	4	18	theme	diabetic	731:738	arg1	rats					740:743	STZ-induced diabetic rats	719:743	STZ-induced diabetic rats	719:743	Our data indicated that RK relieved the symptoms of hyperglycemia, hyperlipidemia in STZ-induced diabetic rats.					
36444040	1	19	theme	red	194:196	arg1	RK					211:212	RK	211:212	RK	211:212	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	1	19	theme	red	194:196	arg1	bean					205:208	red kidney bean	194:208	red kidney bean (RK)	194:213	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	2	20	theme	RK	426:427	arg1	mechanism					413:421	mechanism	413:421	mechanism of RK	413:427	In this study, the antidiabetic effect and mechanism of RK are investigated by serum metabolomics and high-throughput sequencing.					
36444040	2	20	theme	RK	426:427	arg1	effect					402:407	the antidiabetic effect	385:407	the antidiabetic effect	385:407	In this study, the antidiabetic effect and mechanism of RK are investigated by serum metabolomics and high-throughput sequencing.					
36444040	4	21	theme	STZ-induced	719:729	arg1	rats					740:743	STZ-induced diabetic rats	719:743	STZ-induced diabetic rats	719:743	Our data indicated that RK relieved the symptoms of hyperglycemia, hyperlipidemia in STZ-induced diabetic rats.					
36444040	1	22	theme	kidney	198:203	arg1	RK					211:212	RK	211:212	RK	211:212	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	1	22	theme	kidney	198:203	arg1	bean					205:208	red kidney bean	194:208	red kidney bean (RK)	194:213	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	0	23	theme	kidney	25:30	arg1	bean					32:35	red kidney bean	21:35	red kidney bean	21:35	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	5	24	theme	unsaturated	827:837	arg1	acids					845:849	unsaturated fatty acids	827:849	unsaturated fatty acids	827:849	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	0	25	theme	red	21:23	arg1	bean					32:35	red kidney bean	21:35	red kidney bean	21:35	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	6	26	theme	purified	1020:1027	arg1	RKP					1046:1048	RKP	1046:1048	RKP	1046:1048	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	6	26	theme	purified	1020:1027	arg1	polysaccharides					1029:1043	the purified polysaccharides	1016:1043	the purified polysaccharides (RKP)	1016:1049	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	5	27	theme	fatty	839:843	arg1	acids					845:849	unsaturated fatty acids	827:849	unsaturated fatty acids	827:849	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	0	28	theme	metabolic	135:143	arg1	modulation					145:154	lipid metabolic modulation	129:154	lipid metabolic modulation	129:154	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	5	29	theme	acids	845:849	arg1	biosynthesis					811:822	the biosynthesis	807:822	the biosynthesis of unsaturated fatty acids	807:849	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	5	30	theme	gut	870:872	arg1	composition					885:895	gut microbiota composition	870:895	gut microbiota composition	870:895	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	2	31	theme	antidiabetic	389:400	arg1	effect					402:407	the antidiabetic effect	385:407	the antidiabetic effect	385:407	In this study, the antidiabetic effect and mechanism of RK are investigated by serum metabolomics and high-throughput sequencing.					
36444040	2	32	theme	serum	449:453	arg1	metabolomics					455:466	serum metabolomics	449:466	serum metabolomics	449:466	In this study, the antidiabetic effect and mechanism of RK are investigated by serum metabolomics and high-throughput sequencing.					
36444040	1	33	theme	underlying	290:299	arg1	mechanism					301:309	the underlying mechanism	286:309	the underlying mechanism	286:309	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	0	34	theme	lipid	129:133	arg1	modulation					145:154	lipid metabolic modulation	129:154	lipid metabolic modulation	129:154	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	3	35	theme	diabetic	619:626	arg1	rats					628:631	type 2 diabetic rats	612:631	type 2 diabetic rats	612:631	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	3	36	theme	lipid	591:595	arg1	homeostasis					597:607	lipid homeostasis	591:607	lipid homeostasis	591:607	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	0	37	from	hyperlipidemia	67:80	arg1	rats					101:104	type 2 diabetic rats	85:104	type 2 diabetic rats	85:104	Polysaccharides from red kidney bean alleviating hyperglycemia and hyperlipidemia in type 2 diabetic rats via gut microbiota and lipid metabolic modulation.					
36444040	1	38	from	activity	248:255	arg1	mice					276:279	type 2 diabetic mice	260:279	type 2 diabetic mice	260:279	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	4	39	theme	hyperglycemia	686:698	arg1	symptoms					674:681	the symptoms	670:681	the symptoms of hyperglycemia, hyperlipidemia in STZ-induced diabetic rats	670:743	Our data indicated that RK relieved the symptoms of hyperglycemia, hyperlipidemia in STZ-induced diabetic rats.					
36444040	7	40	theme	potential	1160:1168	arg1	RKP					1152:1154	RKP	1152:1154	RKP	1152:1154	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	7	40	theme	potential	1160:1168	arg1	supplement					1188:1197	potential effective dietary supplement	1160:1197	potential effective dietary supplement for type 2 diabetic individuals	1160:1229	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	5	41	theme	key	925:927	arg1	genera					929:934	key genera	925:934	key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia	925:996	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	1	42	theme	significant	223:233	arg1	activity					248:255	significant antidiabetic activity	223:255	significant antidiabetic activity in type 2 diabetic mice	223:279	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	6	43	from	component	1093:1101	arg1	RK					1106:1107	RK	1106:1107	RK	1106:1107	We further found the purified polysaccharides (RKP) were identified as the core biofunctional component in RK.					
36444040	5	44	theme	microbiota	874:883	arg1	composition					885:895	gut microbiota composition	870:895	gut microbiota composition	870:895	RK not only improved the metabolic disturbance by regulating the biosynthesis of unsaturated fatty acids, but also modified gut microbiota composition by selectively enriching in key genera of Bacteroides, Phascolarctobacterium, Succinivibrio, Blautia.					
36444040	3	45	from	improvement	564:574	arg1	rats					628:631	type 2 diabetic rats	612:631	type 2 diabetic rats	612:631	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	3	45	from	improvement	564:574	arg1	homeostasis					597:607	lipid homeostasis	591:607	lipid homeostasis	591:607	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	3	45	from	improvement	564:574	arg1	glucose					579:585	glucose	579:585	glucose	579:585	In addition, the key component was identified by evaluating the improvement on glucose and lipid homeostasis in type 2 diabetic rats.					
36444040	1	46	theme	antidiabetic	235:246	arg1	activity					248:255	significant antidiabetic activity	223:255	significant antidiabetic activity in type 2 diabetic mice	223:279	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	1	47	theme	core	319:322	arg1	component					335:343	the core functional component	315:343	the core functional component	315:343	Crude polysaccharides extracted from red kidney bean (RK) display significant antidiabetic activity in type 2 diabetic mice, but the underlying mechanism and the core functional component has not been elucidated.					
36444040	7	48	theme	effective	1170:1178	arg1	RKP					1152:1154	RKP	1152:1154	RKP	1152:1154	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	7	48	theme	effective	1170:1178	arg1	supplement					1188:1197	potential effective dietary supplement	1160:1197	potential effective dietary supplement for type 2 diabetic individuals	1160:1229	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
36444040	7	49	theme	diabetic	1210:1217	arg1	individuals					1219:1229	type 2 diabetic individuals	1203:1229	type 2 diabetic individuals	1203:1229	Our present studies provide evidence that RKP are potential effective dietary supplement for type 2 diabetic individuals.					
37087241	1	0	theme	chitosan	325:332	arg1	%					347:347	0-0.25%	341:347	0-0.25%	341:347	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	0	theme	chitosan	325:332	arg1	amount					302:307	the amount	298:307	the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v)	298:423	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	0	theme	chitosan	325:332	arg1	chitosan					325:332	carboxylated chitosan	312:332	carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v)	312:423	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	2	1	theme	insoluble	573:581	arg1	complexes					583:591	soluble or insoluble complexes	562:591	soluble or insoluble complexes	562:591	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	5	2	theme	gelatin	905:911	arg1	complexation					884:895	complexation	884:895	complexation of fish gelatin with carboxylated chitosan	884:938	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	1	3	theme	carboxylated	245:256	arg1	chitosan					258:265	carboxylated chitosan	245:265	carboxylated chitosan	245:265	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	0	4	theme	Phase	75:79	arg1	behavior					81:88	Phase behavior	75:88	Phase behavior	75:88	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	3	5	theme	chitosan	641:648	arg1	system					658:663	the fish gelatin-carboxylated chitosan complex system	611:663	the fish gelatin-carboxylated chitosan complex system	611:663	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	5	6	from	α-helix	969:975	arg1	shift					954:958	a shift	952:958	a shift from the α-helix to the β-sheet structure of fish gelatin	952:1016	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	0	7	theme	structural	94:103	arg1	properties					105:114	structural properties	94:114	structural properties	94:114	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	8	8	theme	chitosan	1448:1455	arg1	systems					1465:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	2	9	theme	soluble	562:568	arg1	complexes					583:591	soluble or insoluble complexes	562:591	soluble or insoluble complexes	562:591	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	8	10	theme	complex	1457:1463	arg1	systems					1465:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	8	11	theme	matrices	1499:1506	arg1	design					1480:1485	the design	1476:1485	the design of new food matrices	1476:1506	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	4	12	theme	fluorescence	735:746	arg1	spectroscopy					748:759	fluorescence spectroscopy	735:759	fluorescence spectroscopy	735:759	UV and fluorescence spectroscopy indicated that the carboxylated chitosan changed the tertiary conformation of fish gelatin.					
37087241	8	13	from	use	1415:1417	arg1	design					1480:1485	the design	1476:1485	the design of new food matrices	1476:1506	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	7	14	theme	composite	1183:1191	arg1	coacervates					1193:1203	the composite coacervates	1179:1203	the composite coacervates	1179:1203	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	4	15	theme	gelatin	844:850	arg1	conformation					823:834	the tertiary conformation	810:834	the tertiary conformation of fish gelatin	810:850	UV and fluorescence spectroscopy indicated that the carboxylated chitosan changed the tertiary conformation of fish gelatin.					
37087241	6	16	theme	carboxylated	1075:1086	arg1	chitosan					1088:1095	carboxylated chitosan	1075:1095	carboxylated chitosan	1075:1095	In particular, at pH 5, the fish gelatin complexed with carboxylated chitosan had a disordered structure.					
37087241	7	17	theme	new	1344:1346	arg1	structure					1364:1372	a new lamellar porous structure	1342:1372	a new lamellar porous structure	1342:1372	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	7	18	theme	porous	1357:1362	arg1	structure					1364:1372	a new lamellar porous structure	1342:1372	a new lamellar porous structure	1342:1372	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	7	19	theme	coacervates	1193:1203	arg1	microscopy					1165:1174	scanning electron microscopy	1147:1174	scanning electron microscopy	1147:1174	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	7	19	theme	coacervates	1193:1203	arg1	diffraction					1131:1141	X-ray diffraction	1125:1141	X-ray diffraction	1125:1141	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	3	20	theme	chitosan	696:703	arg1	concentration					705:717	a carboxylated chitosan concentration	681:717	a carboxylated chitosan concentration of 0.2%	681:725	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	2	21	theme	Zeta	426:429	arg1	potential					431:439	Zeta potential	426:439	Zeta potential	426:439	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	5	22	theme	β-sheet	984:990	arg1	structure					992:1000	the β-sheet structure	980:1000	the β-sheet structure of fish gelatin	980:1016	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	8	23	theme	food	1494:1497	arg1	matrices					1499:1506	new food matrices	1490:1506	new food matrices	1490:1506	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	1	24	theme	phase	162:166	arg1	behavior					168:175	phase behavior	162:175	phase behavior	162:175	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	24	theme	phase	162:166	arg1	properties					192:201	structural properties	181:201	structural properties	181:201	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	24	theme	phase	162:166	arg1	function					272:279	a function	270:279	a function of pH	270:285	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	0	25	theme	complex	11:17	arg1	coacervation					19:30	pH-induced complex coacervation	0:30	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.	0:115	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	7	26	theme	electrostatic	1228:1240	arg1	interaction					1242:1252	electrostatic interaction	1228:1252	electrostatic interaction between the two	1228:1268	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	5	27	with	complexation	884:895	arg1	chitosan					931:938	carboxylated chitosan	918:938	carboxylated chitosan	918:938	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	6	28	theme	fish	1047:1050	arg1	gelatin					1052:1058	the fish gelatin	1043:1058	the fish gelatin complexed with carboxylated chitosan	1043:1095	In particular, at pH 5, the fish gelatin complexed with carboxylated chitosan had a disordered structure.					
37087241	0	29	theme	pH-induced	0:9	arg1	coacervation					19:30	pH-induced complex coacervation	0:30	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.	0:115	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	1	30	dep	added	334:338	arg1	%					347:347	0-0.25%	341:347	0-0.25%	341:347	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	30	dep	added	334:338	arg1	chitosan					325:332	carboxylated chitosan	312:332	carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v)	312:423	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	30	dep	added	334:338	arg1	w/v					350:352	w/v	350:352	w/v	350:352	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	6	31	contain	had	1097:1099	arg2	structure					1114:1122	a disordered structure	1101:1122	a disordered structure	1101:1122	In particular, at pH 5, the fish gelatin complexed with carboxylated chitosan had a disordered structure.					
37087241	6	31	contain	had	1097:1099	arg1	gelatin					1052:1058	the fish gelatin	1043:1058	the fish gelatin complexed with carboxylated chitosan	1043:1095	In particular, at pH 5, the fish gelatin complexed with carboxylated chitosan had a disordered structure.					
37087241	3	32	theme	system	658:663	arg1	greatest					669:676	greatest	669:676	greatest	669:676	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	3	32	theme	system	658:663	arg1	turbidity					598:606	The turbidity	594:606	The turbidity of the fish gelatin-carboxylated chitosan complex system	594:663	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	7	33	theme	lamellar	1348:1355	arg1	structure					1364:1372	a new lamellar porous structure	1342:1372	a new lamellar porous structure	1342:1372	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	7	34	theme	electron	1156:1163	arg1	microscopy					1165:1174	scanning electron microscopy	1147:1174	scanning electron microscopy	1147:1174	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	2	35	theme	gelatin	520:526	arg1	coalescence					500:510	the complex coalescence	488:510	the complex coalescence of fish gelatin and carboxylated chitosan	488:552	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	8	36	theme	fish	1422:1425	arg1	systems					1465:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	4	37	theme	tertiary	814:821	arg1	conformation					823:834	the tertiary conformation	810:834	the tertiary conformation of fish gelatin	810:850	UV and fluorescence spectroscopy indicated that the carboxylated chitosan changed the tertiary conformation of fish gelatin.					
37087241	1	38	theme	structural	181:190	arg1	behavior					168:175	phase behavior	162:175	phase behavior	162:175	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	38	theme	structural	181:190	arg1	properties					192:201	structural properties	181:201	structural properties	181:201	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	38	theme	structural	181:190	arg1	function					272:279	a function	270:279	a function of pH	270:285	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	39	theme	pH	284:285	arg1	behavior					168:175	phase behavior	162:175	phase behavior	162:175	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	39	theme	pH	284:285	arg1	properties					192:201	structural properties	181:201	structural properties	181:201	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	39	theme	pH	284:285	arg1	function					272:279	a function	270:279	a function of pH	270:285	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	2	40	theme	fish	515:518	arg1	gelatin					520:526	fish gelatin	515:526	fish gelatin	515:526	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	3	41	theme	fish	615:618	arg1	system					658:663	the fish gelatin-carboxylated chitosan complex system	611:663	the fish gelatin-carboxylated chitosan complex system	611:663	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	7	42	theme	scanning	1147:1154	arg1	microscopy					1165:1174	scanning electron microscopy	1147:1174	scanning electron microscopy	1147:1174	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	0	43	theme	gelatin	40:46	arg1	coacervation					19:30	pH-induced complex coacervation	0:30	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.	0:115	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	3	44	theme	gelatin-carboxylated	620:639	arg1	system					658:663	the fish gelatin-carboxylated chitosan complex system	611:663	the fish gelatin-carboxylated chitosan complex system	611:663	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	1	45	dep	behavior	168:175	arg1	the					158:160	the	158:160	the	158:160	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	7	46	theme	X-ray	1125:1129	arg1	diffraction					1131:1141	X-ray diffraction	1125:1141	X-ray diffraction	1125:1141	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	0	47	theme	fish	35:38	arg1	gelatin					40:46	fish gelatin	35:46	fish gelatin	35:46	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	1	48	with	properties	192:201	arg1	chitosan					258:265	carboxylated chitosan	245:265	carboxylated chitosan	245:265	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	8	49	theme	new	1490:1492	arg1	matrices					1499:1506	new food matrices	1490:1506	new food matrices	1490:1506	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	5	50	theme	Circular	853:860	arg1	dichroism					862:870	Circular dichroism	853:870	Circular dichroism	853:870	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	1	51	theme	fish	206:209	arg1	coacervation					227:238	fish gelatin complex coacervation	206:238	fish gelatin complex coacervation	206:238	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	0	52	theme	carboxylated	52:63	arg1	chitosan					65:72	carboxylated chitosan	52:72	carboxylated chitosan	52:72	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	2	53	theme	complex	492:498	arg1	coalescence					500:510	the complex coalescence	488:510	the complex coalescence of fish gelatin and carboxylated chitosan	488:552	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	1	54	with	behavior	168:175	arg1	chitosan					258:265	carboxylated chitosan	245:265	carboxylated chitosan	245:265	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	8	55	theme	gelatin-carboxylated	1427:1446	arg1	systems					1465:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	fish gelatin-carboxylated chitosan complex systems	1422:1471	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	6	56	theme	disordered	1103:1112	arg1	structure					1114:1122	a disordered structure	1101:1122	a disordered structure	1101:1122	In particular, at pH 5, the fish gelatin complexed with carboxylated chitosan had a disordered structure.					
37087241	5	57	theme	carboxylated	918:929	arg1	chitosan					931:938	carboxylated chitosan	918:938	carboxylated chitosan	918:938	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	2	58	theme	chitosan	545:552	arg1	coalescence					500:510	the complex coalescence	488:510	the complex coalescence of fish gelatin and carboxylated chitosan	488:552	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	1	59	theme	fish	373:376	arg1	gelatin					378:384	the fish gelatin	369:384	the fish gelatin concentration constant	369:407	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	4	60	theme	fish	839:842	arg1	gelatin					844:850	fish gelatin	839:850	fish gelatin	839:850	UV and fluorescence spectroscopy indicated that the carboxylated chitosan changed the tertiary conformation of fish gelatin.					
37087241	7	61	theme	carboxylated	1312:1323	arg1	chitosan					1325:1332	the carboxylated chitosan	1308:1332	the carboxylated chitosan	1308:1332	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	8	62	theme	systems	1465:1471	arg1	use					1415:1417	the use	1411:1417	the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices	1411:1506	These findings may in future enable the use of fish gelatin-carboxylated chitosan complex systems in the design of new food matrices.					
37087241	2	63	theme	carboxylated	532:543	arg1	chitosan					545:552	carboxylated chitosan	532:552	carboxylated chitosan	532:552	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	1	64	theme	gelatin	378:384	arg1	constant					400:407	the fish gelatin concentration constant	369:407	the fish gelatin concentration constant	369:407	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	4	65	theme	carboxylated	780:791	arg1	chitosan					793:800	the carboxylated chitosan	776:800	the carboxylated chitosan	776:800	UV and fluorescence spectroscopy indicated that the carboxylated chitosan changed the tertiary conformation of fish gelatin.					
37087241	3	66	theme	%	725:725	arg1	concentration					705:717	a carboxylated chitosan concentration	681:717	a carboxylated chitosan concentration of 0.2%	681:725	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	1	67	theme	gelatin	211:217	arg1	coacervation					227:238	fish gelatin complex coacervation	206:238	fish gelatin complex coacervation	206:238	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	68	theme	concentration	386:398	arg1	constant					400:407	the fish gelatin concentration constant	369:407	the fish gelatin concentration constant	369:407	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	0	69	dep	coacervation	19:30	arg1	behavior					81:88	Phase behavior	75:88	Phase behavior	75:88	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	0	69	dep	coacervation	19:30	arg1	properties					105:114	structural properties	94:114	structural properties	94:114	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	7	70	theme	molecular	1279:1287	arg1	interaction					1289:1299	molecular interaction	1279:1299	molecular interaction within the carboxylated chitosan	1279:1332	X-ray diffraction and scanning electron microscopy of the composite coacervates both investigated that electrostatic interaction between the two replaced molecular interaction within the carboxylated chitosan to form a new lamellar porous structure.					
37087241	1	71	theme	complex	219:225	arg1	coacervation					227:238	fish gelatin complex coacervation	206:238	fish gelatin complex coacervation	206:238	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	2	72	theme	electrostatic	456:468	arg1	interaction					470:480	electrostatic interaction	456:480	electrostatic interaction	456:480	Zeta potential indicated that electrostatic interaction drove the complex coalescence of fish gelatin and carboxylated chitosan to form soluble or insoluble complexes.					
37087241	3	73	theme	complex	650:656	arg1	system					658:663	the fish gelatin-carboxylated chitosan complex system	611:663	the fish gelatin-carboxylated chitosan complex system	611:663	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	5	74	theme	fish	1005:1008	arg1	gelatin					1010:1016	fish gelatin	1005:1016	fish gelatin	1005:1016	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	1	75	theme	study	133:137	arg1	aim					121:123	The aim	117:123	The aim of this study	117:137	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	76	theme	coacervation	227:238	arg1	behavior					168:175	phase behavior	162:175	phase behavior	162:175	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	76	theme	coacervation	227:238	arg1	properties					192:201	structural properties	181:201	structural properties	181:201	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	76	theme	coacervation	227:238	arg1	function					272:279	a function	270:279	a function of pH	270:285	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	0	77	theme	chitosan	65:72	arg1	coacervation					19:30	pH-induced complex coacervation	0:30	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.	0:115	pH-induced complex coacervation of fish gelatin and carboxylated chitosan: Phase behavior and structural properties.					
37087241	1	78	theme	carboxylated	312:323	arg1	%					347:347	0-0.25%	341:347	0-0.25%	341:347	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	1	78	theme	carboxylated	312:323	arg1	chitosan					325:332	carboxylated chitosan	312:332	carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v)	312:423	The aim of this study was to investigate the phase behavior and structural properties of fish gelatin complex coacervation with carboxylated chitosan as a function of pH by varying the amount of carboxylated chitosan added (0-0.25%, w/v) while keeping the fish gelatin concentration constant at 0.667% (w/v).					
37087241	5	79	theme	gelatin	1010:1016	arg1	structure					992:1000	the β-sheet structure	980:1000	the β-sheet structure of fish gelatin	980:1016	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
37087241	3	80	theme	carboxylated	683:694	arg1	concentration					705:717	a carboxylated chitosan concentration	681:717	a carboxylated chitosan concentration of 0.2%	681:725	The turbidity of the fish gelatin-carboxylated chitosan complex system was greatest at a carboxylated chitosan concentration of 0.2%.					
37087241	5	81	theme	fish	900:903	arg1	gelatin					905:911	fish gelatin	900:911	fish gelatin	900:911	Circular dichroism showed that complexation of fish gelatin with carboxylated chitosan resulted in a shift from the α-helix to the β-sheet structure of fish gelatin.					
35348624	9	0	theme	diminished	1365:1374	arg1	ability					1376:1382	a diminished ability	1363:1382	a diminished ability to dissipate stress during a ramp-hold	1363:1421	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	6	1	theme	SLRP	953:956	arg1	cervices					967:974	SLRP knockout cervices	953:974	SLRP knockout cervices	953:974	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	4	2	theme	cyclic	674:679	arg1	load-unload					681:691	cyclic load-unload	674:691	cyclic load-unload	674:691	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	10	3	theme	combined	1439:1446	arg1	loss					1448:1451	a combined loss	1437:1451	a combined loss of decorin and biglycan	1437:1475	In mice with a combined loss of decorin and biglycan, the pregnant cervix loses its extensibility, compliance, and viscoelasticity.					
35348624	6	4	theme	equilibrium	990:1000	arg1	properties					1011:1020	the same equilibrium material properties	981:1020	the same equilibrium material properties	981:1020	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	7	5	theme	time-dependent	1128:1141	arg1	behavior					1154:1161	time-dependent relaxation behavior	1128:1161	time-dependent relaxation behavior	1128:1161	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	5	6	theme	three-dimensional	872:888	arg1	deformation					896:906	the cervix's three-dimensional large deformation	859:906	the cervix's three-dimensional large deformation equilibrium behavior	859:927	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	8	7	theme	rupture	1229:1235	arg1	properties					1237:1246	inferior rupture properties	1220:1246	inferior rupture properties	1220:1246	Loss of decorin in nonpregnant (NP) cervices results in inferior rupture properties.					
35348624	4	8	theme	cervix	558:563	arg1	specimens					565:573	whole cervix specimens	552:573	whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan,	552:654	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	8	9	theme	decorin	1172:1178	arg1	Loss					1164:1167	Loss	1164:1167	Loss of decorin in nonpregnant (NP) cervices	1164:1207	Loss of decorin in nonpregnant (NP) cervices results in inferior rupture properties.					
35348624	11	10	theme	viscoelastic	1648:1659	arg1	properties					1670:1679	viscoelastic material properties	1648:1679	viscoelastic material properties	1648:1679	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	7	11	theme	impact	1109:1114	arg1	rupture					1116:1122	SLRPs impact rupture	1103:1122	SLRPs impact rupture	1103:1122	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	4	12	theme	nonpregnant	580:590	arg1	mice					619:622	nonpregnant and late pregnant knockout mice	580:622	nonpregnant and late pregnant knockout mice	580:622	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	4	13	theme	load-to-failure	709:723	arg1	tests					736:740	load-to-failure mechanical tests	709:740	load-to-failure mechanical tests	709:740	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	11	14	theme	healthy	1686:1692	arg1	cervix					1714:1719	a healthy, remodeled pregnant cervix	1684:1719	a healthy, remodeled pregnant cervix	1684:1719	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	2	15	theme	stiff	276:280	arg1	material					282:289	a stiff material	274:289	a stiff material	274:289	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	3	16	theme	material	477:484	arg1	properties					486:495	overall tissue material properties	462:495	overall tissue material properties	462:495	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	8	17	theme	nonpregnant	1183:1193	arg1	cervices					1200:1207	nonpregnant (NP) cervices	1183:1207	nonpregnant (NP) cervices	1183:1207	Loss of decorin in nonpregnant (NP) cervices results in inferior rupture properties.					
35348624	2	18	theme	proper	146:151	arg1	regulation					153:162	The proper regulation	142:162	The proper regulation of extracellular matrix (ECM) turnover	142:201	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	5	19	theme	bundle	816:821	arg1	waviness					823:830	collagen fiber bundle waviness	801:830	collagen fiber bundle waviness	801:830	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	5	20	theme	equilibrium	908:918	arg1	behavior					920:927	the cervix's three-dimensional large deformation equilibrium behavior	859:927	the cervix's three-dimensional large deformation equilibrium behavior	859:927	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	5	21	theme	composite	760:768	arg1	model					779:783	a fiber composite material model	752:783	a fiber composite material model	752:783	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	10	22	with	mice	1427:1430	arg1	loss					1448:1451	a combined loss	1437:1451	a combined loss of decorin and biglycan	1437:1475	In mice with a combined loss of decorin and biglycan, the pregnant cervix loses its extensibility, compliance, and viscoelasticity.					
35348624	7	23	theme	SLRPs	1103:1107	arg1	rupture					1116:1122	SLRPs impact rupture	1103:1122	SLRPs impact rupture	1103:1122	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	7	24	theme	ramp-hold	1080:1088	arg1	tests					1090:1094	the load-to-failure and ramp-hold tests	1056:1094	the load-to-failure and ramp-hold tests	1056:1094	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	1	25	theme	Cervical	85:92	arg1	remodeling					94:103	Cervical remodeling	85:103	Cervical remodeling	85:103	Cervical remodeling is critical for a healthy pregnancy.					
35348624	3	26	theme	fiber	423:427	arg1	assembly					429:436	structural fiber assembly	412:436	structural fiber assembly	412:436	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	0	27	theme	Mechanical	0:9	arg1	Response					11:18	Mechanical Response	0:18	Mechanical Response of Mouse Cervices	0:36	Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy.					
35348624	9	28	theme	SLRP-deficient	1337:1350	arg1	tissue					1352:1357	the SLRP-deficient tissue	1333:1357	the SLRP-deficient tissue	1333:1357	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	10	29	theme	decorin	1456:1462	arg1	loss					1448:1451	a combined loss	1437:1451	a combined loss of decorin and biglycan	1437:1475	In mice with a combined loss of decorin and biglycan, the pregnant cervix loses its extensibility, compliance, and viscoelasticity.					
35348624	2	30	theme	compliant	296:304	arg1	tissue					332:337	a compliant, extensible, viscoelastic tissue	294:337	a compliant, extensible, viscoelastic tissue prepared for delivery	294:359	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	3	31	theme	Small	362:366	arg1	proteoglycans					381:393	Small leucine-rich proteoglycans	362:393	Small leucine-rich proteoglycans (SLRPs)	362:401	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	3	31	theme	Small	362:366	arg1	SLRPs					396:400	SLRPs	396:400	SLRPs	396:400	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	6	32	theme	knockout	958:965	arg1	cervices					967:974	SLRP knockout cervices	953:974	SLRP knockout cervices	953:974	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	7	33	theme	load-to-failure	1060:1074	arg1	tests					1090:1094	the load-to-failure and ramp-hold tests	1056:1094	the load-to-failure and ramp-hold tests	1056:1094	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	6	34	theme	material	1002:1009	arg1	properties					1011:1020	the same equilibrium material properties	981:1020	the same equilibrium material properties	981:1020	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	11	35	theme	cervix	1714:1719	arg1	properties					1670:1679	viscoelastic material properties	1648:1679	viscoelastic material properties	1648:1679	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	11	35	theme	cervix	1714:1719	arg1	extensibility					1630:1642	crucial extensibility	1622:1642	crucial extensibility	1622:1642	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	5	36	theme	fiber	810:814	arg1	waviness					823:830	collagen fiber bundle waviness	801:830	collagen fiber bundle waviness	801:830	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	3	37	theme	leucine-rich	368:379	arg1	proteoglycans					381:393	Small leucine-rich proteoglycans	362:393	Small leucine-rich proteoglycans (SLRPs)	362:401	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	3	37	theme	leucine-rich	368:379	arg1	SLRPs					396:400	SLRPs	396:400	SLRPs	396:400	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	4	38	theme	whole	552:556	arg1	specimens					565:573	whole cervix specimens	552:573	whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan,	552:654	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	8	39	from	Loss	1164:1167	arg1	cervices					1200:1207	nonpregnant (NP) cervices	1183:1207	nonpregnant (NP) cervices	1183:1207	Loss of decorin in nonpregnant (NP) cervices results in inferior rupture properties.					
35348624	4	40	theme	mechanical	725:734	arg1	tests					736:740	load-to-failure mechanical tests	709:740	load-to-failure mechanical tests	709:740	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	3	41	theme	overall	462:468	arg1	properties					486:495	overall tissue material properties	462:495	overall tissue material properties	462:495	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	5	42	theme	fiber	754:758	arg1	model					779:783	a fiber composite material model	752:783	a fiber composite material model	752:783	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	10	43	theme	pregnant	1482:1489	arg1	cervix					1491:1496	the pregnant cervix	1478:1496	the pregnant cervix	1478:1496	In mice with a combined loss of decorin and biglycan, the pregnant cervix loses its extensibility, compliance, and viscoelasticity.					
35348624	2	44	theme	matrix	181:186	arg1	turnover					194:201	extracellular matrix (ECM) turnover	167:201	extracellular matrix (ECM) turnover	167:201	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	4	45	from	mice	619:622	arg1	specimens					565:573	whole cervix specimens	552:573	whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan,	552:654	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	3	46	theme	cervical	445:452	arg1	ECM					454:456	the cervical ECM	441:456	the cervical ECM	441:456	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	0	47	theme	Cervices	29:36	arg1	Response					11:18	Mechanical Response	0:18	Mechanical Response of Mouse Cervices	0:36	Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy.					
35348624	4	48	theme	mechanical	521:530	arg1	role					532:535	the SLRPs' mechanical role	510:535	the SLRPs' mechanical role	510:535	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	3	49	theme	structural	412:421	arg1	assembly					429:436	structural fiber assembly	412:436	structural fiber assembly	412:436	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	2	50	theme	extracellular	167:179	arg1	matrix					181:186	extracellular matrix	167:186	extracellular matrix (ECM) turnover	167:201	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	2	50	theme	extracellular	167:179	arg1	ECM					189:191	ECM	189:191	ECM	189:191	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	0	51	theme	Mouse	23:27	arg1	Cervices					29:36	Mouse Cervices	23:36	Mouse Cervices	23:36	Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy.					
35348624	4	52	theme	SLRPs	627:631	arg1	specimens					565:573	whole cervix specimens	552:573	whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan,	552:654	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	5	53	theme	material	770:777	arg1	model					779:783	a fiber composite material model	752:783	a fiber composite material model	752:783	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	6	54	theme	nonpregnant	933:943	arg1	tissue					945:950	nonpregnant tissue	933:950	nonpregnant tissue	933:950	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	6	55	contain	have	976:979	arg2	properties					1011:1020	the same equilibrium material properties	981:1020	the same equilibrium material properties	981:1020	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	6	55	contain	have	976:979	arg1	cervices					967:974	SLRP knockout cervices	953:974	SLRP knockout cervices	953:974	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	9	56	theme	extensive	1255:1263	arg1	remodeling					1265:1274	extensive remodeling	1255:1274	extensive remodeling	1255:1274	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	9	57	contain	has	1359:1361	arg2	ability					1376:1382	a diminished ability	1363:1382	a diminished ability to dissipate stress during a ramp-hold	1363:1421	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	9	57	contain	has	1359:1361	arg1	tissue					1352:1357	the SLRP-deficient tissue	1333:1357	the SLRP-deficient tissue	1333:1357	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	5	58	theme	large	890:894	arg1	deformation					896:906	the cervix's three-dimensional large deformation	859:906	the cervix's three-dimensional large deformation equilibrium behavior	859:927	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	8	59	theme	inferior	1220:1227	arg1	properties					1237:1246	inferior rupture properties	1220:1246	inferior rupture properties	1220:1246	Loss of decorin in nonpregnant (NP) cervices results in inferior rupture properties.					
35348624	11	60	dep	healthy	1686:1692	arg1	remodeled					1695:1703	remodeled	1695:1703	remodeled	1695:1703	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	10	61	theme	biglycan	1468:1475	arg1	loss					1448:1451	a combined loss	1437:1451	a combined loss of decorin and biglycan	1437:1475	In mice with a combined loss of decorin and biglycan, the pregnant cervix loses its extensibility, compliance, and viscoelasticity.					
35348624	5	62	theme	deformation	896:906	arg1	behavior					920:927	the cervix's three-dimensional large deformation equilibrium behavior	859:927	the cervix's three-dimensional large deformation equilibrium behavior	859:927	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	2	63	theme	turnover	194:201	arg1	regulation					153:162	The proper regulation	142:162	The proper regulation of extracellular matrix (ECM) turnover	142:201	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	3	64	theme	tissue	470:475	arg1	properties					486:495	overall tissue material properties	462:495	overall tissue material properties	462:495	Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in the cervical ECM and overall tissue material properties.					
35348624	6	65	theme	wild-type	1025:1033	arg1	tissue					1035:1040	wild-type tissue	1025:1040	wild-type tissue	1025:1040	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	9	66	theme	cervical	1277:1284	arg1	strength					1286:1293	cervical strength	1277:1293	cervical strength	1277:1293	After extensive remodeling, cervical strength is similar between all genotypes, but the SLRP-deficient tissue has a diminished ability to dissipate stress during a ramp-hold.					
35348624	11	67	theme	crucial	1622:1628	arg1	extensibility					1630:1642	crucial extensibility	1622:1642	crucial extensibility	1622:1642	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	2	68	dep	compliant	296:304	arg1	viscoelastic					319:330	viscoelastic	319:330	viscoelastic	319:330	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	2	68	dep	compliant	296:304	arg1	extensible					307:316	extensible	307:316	extensible	307:316	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	2	69	from	material	282:289	arg1	tissue					262:267	the tissue	258:267	the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery	258:359	The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, viscoelastic tissue prepared for delivery.					
35348624	1	70	theme	healthy	123:129	arg1	pregnancy					131:139	a healthy pregnancy	121:139	a healthy pregnancy	121:139	Cervical remodeling is critical for a healthy pregnancy.					
35348624	6	71	theme	same	985:988	arg1	properties					1011:1020	the same equilibrium material properties	981:1020	the same equilibrium material properties	981:1020	In nonpregnant tissue, SLRP knockout cervices have the same equilibrium material properties as wild-type tissue.					
35348624	4	72	theme	knockout	610:617	arg1	mice					619:622	nonpregnant and late pregnant knockout mice	580:622	nonpregnant and late pregnant knockout mice	580:622	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35348624	7	73	theme	relaxation	1143:1152	arg1	behavior					1154:1161	time-dependent relaxation behavior	1128:1161	time-dependent relaxation behavior	1128:1161	In contrast, the load-to-failure and ramp-hold tests reveal SLRPs impact rupture and time-dependent relaxation behavior.					
35348624	11	74	theme	material	1661:1668	arg1	properties					1670:1679	viscoelastic material properties	1648:1679	viscoelastic material properties	1648:1679	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	5	75	theme	collagen	801:808	arg1	waviness					823:830	collagen fiber bundle waviness	801:830	collagen fiber bundle waviness	801:830	Further, a fiber composite material model, accounting for collagen fiber bundle waviness, was developed to describe the cervix's three-dimensional large deformation equilibrium behavior.					
35348624	11	76	theme	pregnant	1705:1712	arg1	cervix					1714:1719	a healthy, remodeled pregnant cervix	1684:1719	a healthy, remodeled pregnant cervix	1684:1719	These results suggest that decorin and biglycan are necessary for crucial extensibility and viscoelastic material properties of a healthy, remodeled pregnant cervix.					
35348624	4	77	theme	pregnant	601:608	arg1	mice					619:622	nonpregnant and late pregnant knockout mice	580:622	nonpregnant and late pregnant knockout mice	580:622	To quantify the SLRPs' mechanical role in the cervix, whole cervix specimens from nonpregnant and late pregnant knockout mice of SLRPs, decorin and biglycan, were subjected to cyclic load-unload, ramp-hold, and load-to-failure mechanical tests.					
35940818	0	0	theme	cell	78:81	arg1	membrane					83:90	the cell membrane	74:90	the cell membrane	74:90	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	2	1	theme	L.	641:642	arg1	reuteriKUB-AC5					644:657	L. reuteriKUB-AC5	641:657	L. reuteriKUB-AC5	641:657	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	2	2	theme	protein	737:743	arg1	isolate					745:751	whey protein isolate	732:751	whey protein isolate	732:751	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	2	3	theme	sucrose	612:618	arg1	Combination					572:582	Combination	572:582	Combination of whey protein isolate and sucrose	572:618	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	4	4	theme	enhanced	1034:1041	arg1	survival					1043:1050	an enhanced survival	1031:1050	an enhanced survival	1031:1050	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	5	5	theme	establishing	1193:1204	arg1	conditions					1214:1223	establishing optimal conditions	1193:1223	establishing optimal conditions	1193:1223	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	1	6	from	differences	481:491	arg1	fluidity					510:517	cell membrane fluidity	496:517	cell membrane fluidity	496:517	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	6	from	differences	481:491	arg1	injury					525:530	cell injury	520:530	cell injury	520:530	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	6	from	differences	481:491	arg1	survival					542:549	cell survival	537:549	cell survival	537:549	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	5	7	theme	optimal	1206:1212	arg1	conditions					1214:1223	establishing optimal conditions	1193:1223	establishing optimal conditions	1193:1223	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	0	8	theme	simulated	183:191	arg1	passage					210:216	simulated gastrointestinal passage	183:216	simulated gastrointestinal passage	183:216	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	9	theme	whey	312:315	arg1	protein					317:323	whey protein	312:323	whey protein isolate	312:331	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	4	10	theme	inlet	996:1000	arg1	temperature					1002:1012	the inlet temperature	992:1012	the inlet temperature of 130 °C	992:1022	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	2	11	theme	L.	786:787	arg1	johnsoniiKUNN19-2					789:805	L. johnsoniiKUNN19-2	786:805	L. johnsoniiKUNN19-2	786:805	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	5	12	theme	spray	1296:1300	arg1	drying					1302:1307	spray drying	1296:1307	spray drying	1296:1307	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	4	13	theme	130 °C	1017:1022	arg1	temperature					1002:1012	the inlet temperature	992:1012	the inlet temperature of 130 °C	992:1022	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	5	14	theme	spray	1161:1165	arg1	drying					1167:1172	spray drying	1161:1172	spray drying	1161:1172	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	2	15	theme	cell	666:669	arg1	membrane					671:678	membrane	671:678	membrane	671:678	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	16	theme	cell	496:499	arg1	fluidity					510:517	cell membrane fluidity	496:517	cell membrane fluidity	496:517	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	5	17	theme	sites	1148:1152	arg1	understanding					1124:1136	A thorough understanding	1113:1136	A thorough understanding of injury sites during spray drying	1113:1172	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	1	18	theme	150 °C.	404:410	arg1	Differences					412:422	150 °C. Differences	404:422	150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	404:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	0	19	theme	gastrointestinal	193:208	arg1	passage					210:216	simulated gastrointestinal passage	183:216	simulated gastrointestinal passage	183:216	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	20	theme	membrane	501:508	arg1	fluidity					510:517	cell membrane fluidity	496:517	cell membrane fluidity	496:517	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	2	21	theme	best	766:769	arg1	protection					771:780	the best protection	762:780	the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures	762:853	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	22	from	Differences	412:422	arg1	sucrose					382:388	sucrose	382:388	sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	382:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	22	from	Differences	412:422	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	2	23	theme	reuteriKUB-AC5	644:657	arg1	survival					629:636	survival	629:636	survival	629:636	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	5	24	theme	gastrointestinal	1323:1338	arg1	passage					1340:1346	gastrointestinal passage	1323:1346	gastrointestinal passage	1323:1346	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	0	25	theme	whey	27:30	arg1	protein					32:38	whey protein isolate and sucrose	27:58	protein	32:38	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	0	26	theme	probiotic	118:126	arg1	lactobacilli					128:139	probiotic lactobacilli	118:139	probiotic lactobacilli strains	118:147	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	27	theme	cell	520:523	arg1	injury					525:530	cell injury	520:530	cell injury	520:530	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	4	28	theme	simulated	1057:1065	arg1	digestion					1075:1083	simulated gastric digestion	1057:1083	simulated gastric digestion	1057:1083	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	0	29	theme	strains	141:147	arg1	survival					106:113	survival	106:113	survival of probiotic lactobacilli strains	106:147	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	30	theme	membrane	427:434	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	4	31	theme	free	1101:1104	arg1	cells					1106:1110	the free cells	1097:1110	the free cells	1097:1110	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	0	32	theme	protein	32:38	arg1	role					19:22	role	19:22	role of whey protein isolate and sucrose in protecting the cell membrane	19:90	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	0	33	theme	lactobacilli	128:139	arg1	strains					141:147	probiotic lactobacilli strains	118:147	probiotic lactobacilli strains	118:147	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	34	theme	fatty	436:440	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	35	from	130 °C	393:398	arg1	sucrose					382:388	sucrose	382:388	sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	382:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	35	from	130 °C	393:398	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	2	36	theme	whey	732:735	arg1	isolate					745:751	whey protein isolate	732:751	whey protein isolate	732:751	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	37	theme	Limosilactobacillus	219:237	arg1	johnsoniiKUNN19-2					271:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	0	38	theme	sucrose	52:58	arg1	role					19:22	role	19:22	role of whey protein isolate and sucrose in protecting the cell membrane	19:90	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	39	theme	whey	347:350	arg1	protein					352:358	whey protein	347:358	whey protein	347:358	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	0	40	theme	spray	156:160	arg1	drying					162:167	spray drying	156:167	spray drying	156:167	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	1	41	theme	acid	442:445	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	4	42	theme	microencapsulated	956:972	arg1	cells					974:978	Both microencapsulated cells	951:978	Both microencapsulated cells prepared at the inlet temperature of 130 °C	951:1022	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	4	43	theme	gastric	1067:1073	arg1	digestion					1075:1083	simulated gastric digestion	1057:1083	simulated gastric digestion	1057:1083	Both microencapsulated cells prepared at the inlet temperature of 130 °C showed an enhanced survival upon simulated gastric digestion compared to the free cells.					
35940818	5	44	theme	encapsulant	1229:1239	arg1	formulations					1241:1252	encapsulant formulations	1229:1252	encapsulant formulations	1229:1252	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	2	45	theme	whey	587:590	arg1	isolate					600:606	whey protein isolate	587:606	whey protein isolate	587:606	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	0	46	dep	protein	32:38	arg1	isolate					40:46	isolate	40:46	isolate	40:46	Microencapsulating role of whey protein isolate and sucrose in protecting the cell membrane and enhancing survival of probiotic lactobacilli strains during spray drying, storage, and simulated gastrointestinal passage.					
35940818	5	47	theme	injury	1141:1146	arg1	sites					1148:1152	injury sites	1141:1152	injury sites	1141:1152	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	2	48	theme	isolate	600:606	arg1	Combination					572:582	Combination	572:582	Combination of whey protein isolate and sucrose	572:618	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	49	dep	protein	317:323	arg1	isolate					325:331	isolate	325:331	whey protein isolate	312:331	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	49	dep	protein	317:323	arg1	isolate					360:366	isolate	360:366	isolate	360:366	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	1	50	theme	cell	537:540	arg1	survival					542:549	cell survival	537:549	cell survival	537:549	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	3	51	theme	shelf-life	923:932	arg1	ofmicrocapsules					934:948	the shelf-life ofmicrocapsules	919:948	the shelf-life ofmicrocapsules	919:948	Moreover, a relationship was found between membrane damage and the shelf-life ofmicrocapsules.					
35940818	3	52	theme	membrane	899:906	arg1	damage					908:913	membrane damage	899:913	membrane damage	899:913	Moreover, a relationship was found between membrane damage and the shelf-life ofmicrocapsules.					
35940818	1	53	theme	reuteriKUB-AC5	239:252	arg1	johnsoniiKUNN19-2					271:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	2	54	theme	protein	592:598	arg1	isolate					600:606	whey protein isolate	587:606	whey protein isolate	587:606	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	55	theme	probiotics	463:472	arg1	compositions					447:458	membrane fatty acid compositions	427:458	membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying	427:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	2	56	theme	secondary	834:842	arg1	structures					844:853	protein secondary structures	826:853	protein secondary structures	826:853	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	57	theme	andLactobacillus	254:269	arg1	johnsoniiKUNN19-2					271:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2	219:287	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35940818	5	58	theme	thorough	1115:1122	arg1	understanding					1124:1136	A thorough understanding	1113:1136	A thorough understanding of injury sites during spray drying	1113:1172	A thorough understanding of injury sites during spray drying will contribute to establishing optimal conditions and encapsulant formulations that maintain the cells' viability during spray drying, storage, and gastrointestinal passage.					
35940818	2	59	theme	protein	826:832	arg1	structures					844:853	protein secondary structures	826:853	protein secondary structures	826:853	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	2	60	from	changes	815:821	arg1	structures					844:853	protein secondary structures	826:853	protein secondary structures	826:853	Combination of whey protein isolate and sucrose improved survival of L. reuteriKUB-AC5, whose cell membrane were more fluid and more sensitive to stress, while whey protein isolate provided the best protection for L. johnsoniiKUNN19-2 against changes in protein secondary structures.					
35940818	1	61	theme	spray	558:562	arg1	drying					564:569	spray drying	558:569	spray drying	558:569	Limosilactobacillus reuteriKUB-AC5 andLactobacillus johnsoniiKUNN19-2 were spray-dried using whey protein isolate, sucrose, and whey protein isolate combined with sucrose at 130 °C and 150 °C. Differences in membrane fatty acid compositions of probiotics led to differences in cell membrane fluidity, cell injury, and cell survival during spray drying.					
35358577	8	0	theme	wound	1428:1432	arg1	healing					1434:1440	wound healing	1428:1440	wound healing process	1428:1448	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	1	1	theme	cutaneous	185:193	arg1	scaffold					195:202	bio-functionalized cutaneous scaffold	166:202	bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair	166:331	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	6	2	theme	efficient	1103:1111	arg1	property					1124:1131	efficient hemostatic property	1103:1131	efficient hemostatic property	1103:1131	Furthermore, the scaffolds exhibited efficient hemostatic property, based on rat hepatic hemorrhage model.					
35358577	6	3	theme	hemorrhage	1155:1164	arg1	model					1166:1170	rat hepatic hemorrhage model	1143:1170	rat hepatic hemorrhage model	1143:1170	Furthermore, the scaffolds exhibited efficient hemostatic property, based on rat hepatic hemorrhage model.					
35358577	1	4	with	scaffold	195:202	arg1	features					221:228	transparent features	209:228	transparent features for convenient observation, excellent biocompatibility, and high efficiency	209:304	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	4	5	from	adhesion	857:864	arg1	state					873:877	wet state	869:877	wet state	869:877	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	5	6	theme	NIH-3T3	1003:1009	arg1	cells					1022:1026	NIH-3T3 fibroblast cells	1003:1026	NIH-3T3 fibroblast cells	1003:1026	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	9	7	theme	great	1635:1639	arg1	potential					1641:1649	great potential	1635:1649	great potential for clinical treatment of cutaneous wound	1635:1691	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	7	8	theme	SF-SA	1293:1297	arg1	scaffolds					1299:1307	pure SF-SA scaffolds	1288:1307	pure SF-SA scaffolds	1288:1307	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	7	9	theme	mouse	1199:1203	arg1	model					1211:1215	a cutaneous excisional mouse wound model	1176:1215	a cutaneous excisional mouse wound model	1176:1215	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	5	10	dep	In	880:881	arg1	vitro					883:887	vitro	883:887	vitro	883:887	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	5	11	theme	AFAS	1060:1063	arg1	presence					1048:1055	the presence	1044:1055	the presence of AFAS	1044:1063	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	3	12	theme	similar	627:633	arg1	UTS					662:664	UTS	662:664	UTS	662:664	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	12	theme	similar	627:633	arg1	strength					652:659	similar ultimate tensile strength	627:659	similar ultimate tensile strength (UTS)	627:665	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	13	theme	ultimate	635:642	arg1	UTS					662:664	UTS	662:664	UTS	662:664	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	13	theme	ultimate	635:642	arg1	strength					652:659	similar ultimate tensile strength	627:659	similar ultimate tensile strength (UTS)	627:665	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	8	14	theme	process	1442:1448	arg1	integrity					1406:1414	the integrity	1402:1414	the integrity of skin and wound healing process	1402:1448	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	8	15	theme	healing	1434:1440	arg1	process					1442:1448	wound healing process	1428:1448	wound healing process	1428:1448	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	9	16	theme	SF/SA	1604:1608	arg1	hydrogel					1622:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	1	17	theme	wound	320:324	arg1	repair					326:331	wound repair	320:331	wound repair	320:331	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	5	18	theme	fibroblast	1011:1020	arg1	cells					1022:1026	NIH-3T3 fibroblast cells	1003:1026	NIH-3T3 fibroblast cells	1003:1026	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	5	19	theme	excellent	923:931	arg1	biocompatibility					933:948	excellent biocompatibility	923:948	excellent biocompatibility of the scaffold	923:964	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	4	20	from	permeability	830:841	arg1	state					873:877	wet state	869:877	wet state	869:877	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	8	21	theme	collagen	1463:1470	arg1	deposition					1472:1481	collagen deposition	1463:1481	collagen deposition	1463:1481	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	4	22	theme	solvent-casting	722:736	arg1	method					738:743	the solvent-casting method	718:743	the solvent-casting method	718:743	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	6	23	theme	hepatic	1147:1153	arg1	model					1166:1170	rat hepatic hemorrhage model	1143:1170	rat hepatic hemorrhage model	1143:1170	Furthermore, the scaffolds exhibited efficient hemostatic property, based on rat hepatic hemorrhage model.					
35358577	7	24	theme	pure	1288:1291	arg1	scaffolds					1299:1307	pure SF-SA scaffolds	1288:1307	pure SF-SA scaffolds	1288:1307	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	7	25	theme	wound	1205:1209	arg1	model					1211:1215	a cutaneous excisional mouse wound model	1176:1215	a cutaneous excisional mouse wound model	1176:1215	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	0	26	theme	Allantoin-functionalized	0:23	arg1	silk					25:28	Allantoin-functionalized silk	0:28	Allantoin-functionalized silk	0:28	Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.					
35358577	1	27	theme	transparent	209:219	arg1	features					221:228	transparent features	209:228	transparent features for convenient observation, excellent biocompatibility, and high efficiency	209:304	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	5	28	theme	In	880:881	arg1	experiments					898:908	In vitro cellular experiments	880:908	In vitro cellular experiments	880:908	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	3	29	theme	mechanical	581:590	arg1	properties					592:601	excellent mechanical properties	571:601	excellent mechanical properties	571:601	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	7	30	theme	blank	1313:1317	arg1	control					1319:1325	blank control	1313:1325	blank control	1313:1325	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	1	31	theme	clinical	107:114	arg1	application					116:126	clinical application	107:126	clinical application	107:126	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	2	32	theme	sodium	434:439	arg1	alginate					441:448	sodium alginate	434:448	sodium alginate (SA)	434:453	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	2	32	theme	sodium	434:439	arg1	SA					451:452	SA	451:452	SA	451:452	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	2	33	theme	wounds	482:487	arg1	treatment					459:467	treatment	459:467	treatment of cutaneous wounds	459:487	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	7	34	theme	excisional	1188:1197	arg1	model					1211:1215	a cutaneous excisional mouse wound model	1176:1215	a cutaneous excisional mouse wound model	1176:1215	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	3	35	theme	tensile	644:650	arg1	UTS					662:664	UTS	662:664	UTS	662:664	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	35	theme	tensile	644:650	arg1	strength					652:659	similar ultimate tensile strength	627:659	similar ultimate tensile strength (UTS)	627:665	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	9	36	theme	allantoin-functionalized	1579:1602	arg1	hydrogel					1622:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	2	37	theme	cutaneous	472:480	arg1	wounds					482:487	cutaneous wounds	472:487	cutaneous wounds	472:487	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	8	38	theme	wound	1528:1532	arg1	site					1534:1537	wound site	1528:1537	wound site	1528:1537	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	2	39	theme	composite	367:375	arg1	hydrogel					377:384	allantoin-functionalized composite hydrogel	342:384	allantoin-functionalized composite hydrogel	342:384	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	1	40	theme	convenient	234:243	arg1	observation					245:255	convenient observation	234:255	convenient observation	234:255	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	2	41	theme	allantoin-functionalized	342:365	arg1	hydrogel					377:384	allantoin-functionalized composite hydrogel	342:384	allantoin-functionalized composite hydrogel	342:384	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	9	42	theme	wound	1687:1691	arg1	treatment					1664:1672	clinical treatment	1655:1672	clinical treatment of cutaneous wound	1655:1691	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	3	43	theme	SF-SA	528:532	arg1	AFAS					555:558	AFAS	555:558	AFAS	555:558	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	43	theme	SF-SA	528:532	arg1	scaffolds					544:552	The prepared allantoin-functionalized SF-SA composite scaffolds	490:552	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS)	490:559	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	5	44	theme	cells	1022:1026	arg1	proliferation					986:998	proliferation	986:998	proliferation	986:998	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	5	44	theme	cells	1022:1026	arg1	attachment					971:980	attachment	971:980	attachment	971:980	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	6	45	theme	rat	1143:1145	arg1	model					1166:1170	rat hepatic hemorrhage model	1143:1170	rat hepatic hemorrhage model	1143:1170	Furthermore, the scaffolds exhibited efficient hemostatic property, based on rat hepatic hemorrhage model.					
35358577	0	46	theme	transparent	54:64	arg1	scaffold					66:73	alginate transparent scaffold	45:73	alginate transparent scaffold for cutaneous wound healing	45:101	Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.					
35358577	7	47	theme	wound	1254:1258	arg1	closure					1260:1266	wound closure	1254:1266	the wound closure rate	1250:1271	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	8	48	theme	skin	1419:1422	arg1	integrity					1406:1414	the integrity	1402:1414	the integrity of skin and wound healing process	1402:1448	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	0	49	theme	alginate	45:52	arg1	scaffold					66:73	alginate transparent scaffold	45:73	alginate transparent scaffold for cutaneous wound healing	45:101	Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.					
35358577	1	50	theme	excellent	258:266	arg1	biocompatibility					268:283	excellent biocompatibility	258:283	excellent biocompatibility	258:283	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	0	51	theme	cutaneous	79:87	arg1	healing					95:101	cutaneous wound healing	79:101	cutaneous wound healing	79:101	Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.					
35358577	9	52	theme	cutaneous	1677:1685	arg1	wound					1687:1691	cutaneous wound	1677:1691	cutaneous wound	1677:1691	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	3	53	theme	human	697:701	arg1	skin					703:706	human skin	697:706	human skin	697:706	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	2	54	theme	silk	412:415	arg1	SF					426:427	SF	426:427	SF	426:427	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	2	54	theme	silk	412:415	arg1	fibroin					417:423	coupling silk fibroin	403:423	coupling silk fibroin (SF)	403:428	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	9	55	theme	clinical	1655:1662	arg1	treatment					1664:1672	clinical treatment	1655:1672	clinical treatment of cutaneous wound	1655:1691	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	7	56	theme	cutaneous	1178:1186	arg1	model					1211:1215	a cutaneous excisional mouse wound model	1176:1215	a cutaneous excisional mouse wound model	1176:1215	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	5	57	theme	cellular	889:896	arg1	experiments					898:908	In vitro cellular experiments	880:908	In vitro cellular experiments	880:908	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	9	58	theme	transparent	1610:1620	arg1	hydrogel					1622:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	2	59	theme	coupling	403:410	arg1	SF					426:427	SF	426:427	SF	426:427	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	2	59	theme	coupling	403:410	arg1	fibroin					417:423	coupling silk fibroin	403:423	coupling silk fibroin (SF)	403:428	Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds.					
35358577	7	60	theme	closure	1260:1266	arg1	rate					1268:1271	the wound closure rate	1250:1271	the wound closure rate	1250:1271	In a cutaneous excisional mouse wound model, the AFAS significantly improved the wound closure rate, compared with pure SF-SA scaffolds and blank control.					
35358577	4	61	theme	wet	869:871	arg1	state					873:877	wet state	869:877	wet state	869:877	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	8	62	theme	histomorphological	1342:1359	arg1	assessments					1361:1371	the histomorphological assessments	1338:1371	the histomorphological assessments	1338:1371	Moreover, the histomorphological assessments showed that AFAS facilitated the integrity of skin and wound healing process by enhancing collagen deposition, re-epithelialization and vascularization at wound site.					
35358577	3	63	theme	composite	534:542	arg1	AFAS					555:558	AFAS	555:558	AFAS	555:558	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	63	theme	composite	534:542	arg1	scaffolds					544:552	The prepared allantoin-functionalized SF-SA composite scaffolds	490:552	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS)	490:559	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	4	64	theme	moisture	821:828	arg1	permeability					830:841	sufficient moisture permeability	810:841	sufficient moisture permeability	810:841	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	4	65	theme	excellent	847:855	arg1	adhesion					857:864	excellent adhesion	847:864	excellent adhesion	847:864	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	9	66	contain	has	1631:1633	arg1	hydrogel					1622:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	9	66	contain	has	1631:1633	arg2	potential					1641:1649	great potential	1635:1649	great potential for clinical treatment of cutaneous wound	1635:1691	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	4	67	theme	sufficient	810:819	arg1	permeability					830:841	sufficient moisture permeability	810:841	sufficient moisture permeability	810:841	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	1	68	theme	bio-functionalized	166:183	arg1	scaffold					195:202	bio-functionalized cutaneous scaffold	166:202	bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair	166:331	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	4	69	theme	transparent	782:792	arg1	properties					794:803	highly transparent properties	775:803	highly transparent properties	775:803	Besides, the solvent-casting method guaranteed the AFAS to obtain highly transparent properties with sufficient moisture permeability and excellent adhesion in wet state.					
35358577	3	70	theme	prepared	494:501	arg1	AFAS					555:558	AFAS	555:558	AFAS	555:558	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	70	theme	prepared	494:501	arg1	scaffolds					544:552	The prepared allantoin-functionalized SF-SA composite scaffolds	490:552	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS)	490:559	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	71	theme	allantoin-functionalized	503:526	arg1	AFAS					555:558	AFAS	555:558	AFAS	555:558	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	71	theme	allantoin-functionalized	503:526	arg1	scaffolds					544:552	The prepared allantoin-functionalized SF-SA composite scaffolds	490:552	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS)	490:559	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	3	72	theme	excellent	571:579	arg1	properties					592:601	excellent mechanical properties	571:601	excellent mechanical properties	571:601	The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.					
35358577	5	73	theme	scaffold	957:964	arg1	biocompatibility					933:948	excellent biocompatibility	923:948	excellent biocompatibility of the scaffold	923:964	In vitro cellular experiments demonstrated excellent biocompatibility of the scaffold that attachment and proliferation of NIH-3T3 fibroblast cells was promoted in the presence of AFAS.					
35358577	0	74	theme	wound	89:93	arg1	healing					95:101	cutaneous wound healing	79:101	cutaneous wound healing	79:101	Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.					
35358577	9	75	theme	novel	1573:1577	arg1	hydrogel					1622:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	the novel allantoin-functionalized SF/SA transparent hydrogel	1569:1629	The results demonstrate that the novel allantoin-functionalized SF/SA transparent hydrogel has great potential for clinical treatment of cutaneous wound.					
35358577	6	76	theme	hemostatic	1113:1122	arg1	property					1124:1131	efficient hemostatic property	1103:1131	efficient hemostatic property	1103:1131	Furthermore, the scaffolds exhibited efficient hemostatic property, based on rat hepatic hemorrhage model.					
35358577	1	77	dep	it	129:130	arg1	application					116:126	clinical application	107:126	clinical application	107:126	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
35358577	1	78	theme	high	290:293	arg1	efficiency					295:304	high efficiency	290:304	high efficiency	290:304	In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair.					
36007421	8	0	theme	hybrid	1403:1408	arg1	nanomaterials					1420:1432	hybrid colloidal nanomaterials	1403:1432	hybrid colloidal nanomaterials	1403:1432	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	1	theme	ZChNCs	722:727	arg1	aggregation					707:717	the liquid aggregation	696:717	the liquid aggregation of ZChNCs and GO	696:734	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	1	2	theme	liquid	289:294	arg1	assembly					296:303	liquid assembly	289:303	liquid assembly	289:303	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	3	3	theme	planar	535:540	arg1	catchers					542:549	two-dimensional (2D) planar catchers	514:549	two-dimensional (2D) planar catchers of graphene oxide (GO) sheets	514:579	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	8	4	theme	assembly	1482:1489	arg1	dimension					1463:1471	the structural design dimension	1441:1471	the structural design dimension of macro assembly	1441:1489	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	5	theme	dominant	586:593	arg1	strategy					620:627	The dominant electrostatic regulation strategy	582:627	The dominant electrostatic regulation strategy by pH variation	582:643	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	0	6	theme	electrostatic	100:112	arg1	regulation					114:123	electrostatic regulation	100:123	electrostatic regulation	100:123	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	6	7	theme	groups	1181:1186	arg1	ionization					1151:1160	the ionization	1147:1160	the ionization of excess carboxyl groups on the surface of ZChNCs	1147:1211	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	4	8	theme	isolated	752:759	arg1	changes					684:690	three reversible changes	667:690	three reversible changes	667:690	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	8	theme	isolated	752:759	arg1	pH > 7					779:784	pH > 7	779:784	pH > 7	779:784	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	8	theme	isolated	752:759	arg1	state					772:776	the isolated dispersion state	748:776	the isolated dispersion state (pH > 7)	748:785	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	8	9	theme	great	1501:1505	arg1	potentials					1507:1516	great potentials	1501:1516	great potentials in high-performance biodegradable material	1501:1559	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	3	10	dep	two-dimensional	514:528	arg1	2D					531:532	2D	531:532	2D	531:532	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	2	11	theme	liquid	319:324	arg1	aggregation					326:336	the liquid aggregation	315:336	the liquid aggregation of nanomaterials	315:353	However, the liquid aggregation of nanomaterials was less investigated.					
36007421	4	12	theme	regulation	609:618	arg1	strategy					620:627	The dominant electrostatic regulation strategy	582:627	The dominant electrostatic regulation strategy by pH variation	582:643	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	6	13	theme	maximum	1084:1090	arg1	potential					1097:1105	a maximum Zeta potential	1082:1105	a maximum Zeta potential	1082:1105	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	3	14	theme	graphene	554:561	arg1	oxide					563:567	graphene oxide	554:567	graphene oxide (GO) sheets	554:579	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	0	15	theme	nanocrystals	49:60	arg1	aggregation					14:24	Tuning liquid aggregation	0:24	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar	0:85	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	8	16	from	potentials	1507:1516	arg1	material					1552:1559	high-performance biodegradable material	1521:1559	high-performance biodegradable material	1521:1559	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	17	theme	electrostatic	595:607	arg1	strategy					620:627	The dominant electrostatic regulation strategy	582:627	The dominant electrostatic regulation strategy by pH variation	582:643	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	1	18	dep	important	129:137	arg1	structural					139:148	structural	139:148	structural	139:148	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	1	19	theme	great	194:198	arg1	potentials					200:209	great potentials	194:209	great potentials	194:209	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	1	19	theme	great	194:198	arg1	units					150:154	important structural units	129:154	important structural units	129:154	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	0	20	theme	liquid	7:12	arg1	aggregation					14:24	Tuning liquid aggregation	0:24	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar	0:85	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	8	21	theme	new	1390:1392	arg1	class					1394:1398	a new class	1388:1398	a new class of hybrid colloidal nanomaterials	1388:1432	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	22	theme	hybridization	856:868	arg1	pH < 5					877:882	pH < 5	877:882	pH < 5	877:882	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	22	theme	hybridization	856:868	arg1	state					870:874	partially stacked hybridization state	838:874	partially stacked hybridization state (pH < 5)	838:883	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	6	23	from	ionization	1151:1160	arg1	surface					1195:1201	the surface	1191:1201	the surface of ZChNCs	1191:1211	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	0	24	theme	Tuning	0:5	arg1	aggregation					14:24	Tuning liquid aggregation	0:24	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar	0:85	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	8	25	theme	biodegradable	1538:1550	arg1	material					1552:1559	high-performance biodegradable material	1521:1559	high-performance biodegradable material	1521:1559	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	26	theme	stacked	848:854	arg1	pH < 5					877:882	pH < 5	877:882	pH < 5	877:882	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	26	theme	stacked	848:854	arg1	state					870:874	partially stacked hybridization state	838:874	partially stacked hybridization state (pH < 5)	838:883	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	6	27	theme	ZChNCs-GO	1047:1055	arg1	nanohybrids					1057:1067	the ZChNCs-GO nanohybrids	1043:1067	the ZChNCs-GO nanohybrids	1043:1067	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	3	28	theme	one-dimensional	408:422	arg1	ZChNCs					463:468	ZChNCs	463:468	ZChNCs	463:468	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	3	28	theme	one-dimensional	408:422	arg1	nanocrystals					449:460	the one-dimensional (1D) zwitterionic chitin nanocrystals	404:460	the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs)	404:469	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	6	29	theme	carboxyl	1172:1179	arg1	groups					1181:1186	excess carboxyl groups	1165:1186	excess carboxyl groups	1165:1186	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	7	30	with	nanohybrids	1263:1273	arg1	behavior					1292:1299	rheological behavior	1280:1299	rheological behavior	1280:1299	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	2	31	theme	nanomaterials	341:353	arg1	aggregation					326:336	the liquid aggregation	315:336	the liquid aggregation of nanomaterials	315:353	However, the liquid aggregation of nanomaterials was less investigated.					
36007421	7	32	theme	nanomaterials	1354:1366	arg1	assembly					1335:1342	the macro assembly	1325:1342	the macro assembly of liquid nanomaterials	1325:1366	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	7	33	theme	rheological	1280:1290	arg1	behavior					1292:1299	rheological behavior	1280:1299	rheological behavior	1280:1299	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	5	34	theme	aggregation	964:974	arg1	change					947:952	the change	943:952	the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV)	943:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	8	35	theme	nanomaterials	1420:1432	arg1	class					1394:1398	a new class	1388:1398	a new class of hybrid colloidal nanomaterials	1388:1432	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	3	36	theme	sheets	574:579	arg1	catchers					542:549	two-dimensional (2D) planar catchers	514:549	two-dimensional (2D) planar catchers of graphene oxide (GO) sheets	514:579	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	1	37	theme	high-performance	224:239	arg1	materials					253:261	high-performance macroscopic materials	224:261	high-performance macroscopic materials for broad applications	224:284	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	0	38	theme	chitin	42:47	arg1	nanocrystals					49:60	zwitterionic chitin nanocrystals	29:60	zwitterionic chitin nanocrystals	29:60	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	3	39	dep	oxide	563:567	arg1	GO					570:571	GO	570:571	GO	570:571	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	8	40	theme	design	1456:1461	arg1	dimension					1463:1471	the structural design dimension	1441:1471	the structural design dimension of macro assembly	1441:1489	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	6	41	theme	ZChNCs	1206:1211	arg1	surface					1195:1201	the surface	1191:1201	the surface of ZChNCs	1191:1211	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	6	42	theme	excess	1165:1170	arg1	groups					1181:1186	excess carboxyl groups	1165:1186	excess carboxyl groups	1165:1186	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	1	43	theme	macroscopic	241:251	arg1	materials					253:261	high-performance macroscopic materials	224:261	high-performance macroscopic materials for broad applications	224:284	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	0	44	theme	zwitterionic	29:40	arg1	nanocrystals					49:60	zwitterionic chitin nanocrystals	29:60	zwitterionic chitin nanocrystals	29:60	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	5	45	with	aggregation	964:974	arg1	almost>30 mV					1018:1029	almost>30 mV	1018:1029	almost>30 mV	1018:1029	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	5	45	with	aggregation	964:974	arg1	potentials					1006:1015	the higher absolute Zeta potentials	981:1015	the higher absolute Zeta potentials (almost>30 mV)	981:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	3	46	theme	zwitterionic	429:440	arg1	ZChNCs					463:468	ZChNCs	463:468	ZChNCs	463:468	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	3	46	theme	zwitterionic	429:440	arg1	nanocrystals					449:460	the one-dimensional (1D) zwitterionic chitin nanocrystals	404:460	the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs)	404:469	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	8	47	theme	high-performance	1521:1536	arg1	material					1552:1559	high-performance biodegradable material	1521:1559	high-performance biodegradable material	1521:1559	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	5	48	theme	liquid	957:962	arg1	aggregation					964:974	liquid aggregation	957:974	liquid aggregation with the higher absolute Zeta potentials (almost>30 mV)	957:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	4	49	theme	GO	733:734	arg1	aggregation					707:717	the liquid aggregation	696:717	the liquid aggregation of ZChNCs and GO	696:734	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	3	50	theme	chitin	442:447	arg1	ZChNCs					463:468	ZChNCs	463:468	ZChNCs	463:468	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	3	50	theme	chitin	442:447	arg1	nanocrystals					449:460	the one-dimensional (1D) zwitterionic chitin nanocrystals	404:460	the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs)	404:469	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	8	51	theme	structural	1445:1454	arg1	dimension					1463:1471	the structural design dimension	1441:1471	the structural design dimension of macro assembly	1441:1489	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	7	52	theme	liquid	1347:1352	arg1	nanomaterials					1354:1366	liquid nanomaterials	1347:1366	liquid nanomaterials	1347:1366	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	1	53	theme	important	129:137	arg1	potentials					200:209	great potentials	194:209	great potentials	194:209	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	1	53	theme	important	129:137	arg1	units					150:154	important structural units	129:154	important structural units	129:154	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	8	54	theme	colloidal	1410:1418	arg1	nanomaterials					1420:1432	hybrid colloidal nanomaterials	1403:1432	hybrid colloidal nanomaterials	1403:1432	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	5	55	theme	Zeta	1001:1004	arg1	almost>30 mV					1018:1029	almost>30 mV	1018:1029	almost>30 mV	1018:1029	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	5	55	theme	Zeta	1001:1004	arg1	potentials					1006:1015	the higher absolute Zeta potentials	981:1015	the higher absolute Zeta potentials (almost>30 mV)	981:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	7	56	theme	macro	1329:1333	arg1	assembly					1335:1342	the macro assembly	1325:1342	the macro assembly of liquid nanomaterials	1325:1366	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	4	57	theme	homogeneous	788:798	arg1	7 ≥ pH ≥ 5					821:830	7 ≥ pH ≥ 5	821:830	7 ≥ pH ≥ 5	821:830	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	57	theme	homogeneous	788:798	arg1	state					814:818	homogeneous hybridization state	788:818	homogeneous hybridization state (7 ≥ pH ≥ 5)	788:831	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	58	theme	liquid	700:705	arg1	aggregation					707:717	the liquid aggregation	696:717	the liquid aggregation of ZChNCs and GO	696:734	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	7	59	theme	electrostatic	1227:1239	arg1	regulation					1241:1250	the electrostatic regulation	1223:1250	the electrostatic regulation	1223:1250	Besides, the electrostatic regulation endows the nanohybrids with rheological behavior, which is beneficial to the macro assembly of liquid nanomaterials.					
36007421	4	60	theme	dispersion	761:770	arg1	changes					684:690	three reversible changes	667:690	three reversible changes	667:690	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	60	theme	dispersion	761:770	arg1	pH > 7					779:784	pH > 7	779:784	pH > 7	779:784	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	60	theme	dispersion	761:770	arg1	state					772:776	the isolated dispersion state	748:776	the isolated dispersion state (pH > 7)	748:785	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	61	theme	pH	632:633	arg1	variation					635:643	pH variation	632:643	pH variation	632:643	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	3	62	theme	oxide	563:567	arg1	sheets					574:579	graphene oxide (GO) sheets	554:579	graphene oxide (GO) sheets	554:579	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	5	63	theme	higher	985:990	arg1	almost>30 mV					1018:1029	almost>30 mV	1018:1029	almost>30 mV	1018:1029	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	5	63	theme	higher	985:990	arg1	potentials					1006:1015	the higher absolute Zeta potentials	981:1015	the higher absolute Zeta potentials (almost>30 mV)	981:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	3	64	theme	two-dimensional	514:528	arg1	catchers					542:549	two-dimensional (2D) planar catchers	514:549	two-dimensional (2D) planar catchers of graphene oxide (GO) sheets	514:579	Here, we demonstrate that the one-dimensional (1D) zwitterionic chitin nanocrystals (ZChNCs) can be reversibly captured and released by two-dimensional (2D) planar catchers of graphene oxide (GO) sheets.					
36007421	1	65	theme	broad	267:271	arg1	applications					273:284	broad applications	267:284	broad applications	267:284	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
36007421	0	66	theme	oxide	74:78	arg1	planar					80:85	graphene oxide planar	65:85	graphene oxide planar	65:85	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	6	67	theme	Zeta	1092:1095	arg1	potential					1097:1105	a maximum Zeta potential	1082:1105	a maximum Zeta potential	1082:1105	Moreover, the ZChNCs-GO nanohybrids have reached a maximum Zeta potential up to -80 mV, which can be explained by the ionization of excess carboxyl groups on the surface of ZChNCs.					
36007421	5	68	theme	absolute	992:999	arg1	almost>30 mV					1018:1029	almost>30 mV	1018:1029	almost>30 mV	1018:1029	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	5	68	theme	absolute	992:999	arg1	potentials					1006:1015	the higher absolute Zeta potentials	981:1015	the higher absolute Zeta potentials (almost>30 mV)	981:1030	We found there are no sedimentation during the change of liquid aggregation with the higher absolute Zeta potentials (almost>30 mV).					
36007421	4	69	theme	reversible	673:682	arg1	changes					684:690	three reversible changes	667:690	three reversible changes	667:690	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	69	theme	reversible	673:682	arg1	state					772:776	the isolated dispersion state	748:776	the isolated dispersion state (pH > 7)	748:785	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	0	70	theme	graphene	65:72	arg1	planar					80:85	graphene oxide planar	65:85	graphene oxide planar	65:85	Tuning liquid aggregation of zwitterionic chitin nanocrystals by graphene oxide planar catchers via electrostatic regulation.					
36007421	8	71	theme	macro	1476:1480	arg1	assembly					1482:1489	macro assembly	1476:1489	macro assembly	1476:1489	This work provides a new class of hybrid colloidal nanomaterials, opens the structural design dimension of macro assembly and holds great potentials in high-performance biodegradable material.					
36007421	4	72	theme	hybridization	800:812	arg1	7 ≥ pH ≥ 5					821:830	7 ≥ pH ≥ 5	821:830	7 ≥ pH ≥ 5	821:830	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	4	72	theme	hybridization	800:812	arg1	state					814:818	homogeneous hybridization state	788:818	homogeneous hybridization state (7 ≥ pH ≥ 5)	788:831	The dominant electrostatic regulation strategy by pH variation drives that there are three reversible changes for the liquid aggregation of ZChNCs and GO, which were the isolated dispersion state (pH > 7), homogeneous hybridization state (7 ≥ pH ≥ 5), and partially stacked hybridization state (pH < 5), respectively.					
36007421	1	73	theme	biomass	157:163	arg1	nanomaterials					165:177	biomass nanomaterials	157:177	biomass nanomaterials	157:177	As important structural units, biomass nanomaterials have exhibited great potentials to construct high-performance macroscopic materials for broad applications by liquid assembly.					
35617886	11	0	theme	DESs-extracted	1657:1670	arg1	pectins					1672:1678	two DESs-extracted pectins	1653:1678	two DESs-extracted pectins	1653:1678	Moreover, it was found that HCl-extracted pectin was in a colloid state, while two DESs-extracted pectins or CP were in a flow state.					
35617886	1	1	theme	extracting	241:250	arg1	solvents					212:219	eco-friendly deep eutectic solvents	185:219	eco-friendly deep eutectic solvents (DESs)	185:226	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	1	theme	extracting	241:250	arg1	agents					252:257	extracting agents	241:257	extracting agents for the first time	241:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	14	2	theme	functional	2111:2120	arg1	application					2122:2132	the functional application	2107:2132	the functional application of mango peel pectins in the food and pharmaceutical industry	2107:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	1	3	from	extraction	285:294	arg1	peel					318:321	mango peel	312:321	mango peel	312:321	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	11	4	theme	HCl-extracted	1602:1614	arg1	pectin					1616:1621	HCl-extracted pectin	1602:1621	HCl-extracted pectin	1602:1621	Moreover, it was found that HCl-extracted pectin was in a colloid state, while two DESs-extracted pectins or CP were in a flow state.					
35617886	10	5	contain	had	1483:1485	arg1	pectin					1476:1481	HCl-extracted pectin	1462:1481	HCl-extracted pectin	1462:1481	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	10	5	contain	had	1483:1485	arg2	properties					1504:1513	higher viscosity properties	1487:1513	higher viscosity properties	1487:1513	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	1	6	theme	eco-friendly	185:196	arg1	agents					252:257	extracting agents	241:257	extracting agents for the first time	241:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	6	theme	eco-friendly	185:196	arg1	DESs					222:225	DESs	222:225	DESs	222:225	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	6	theme	eco-friendly	185:196	arg1	solvents					212:219	eco-friendly deep eutectic solvents	185:219	eco-friendly deep eutectic solvents (DESs)	185:226	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	2	7	theme	experimental	521:532	arg1	design					514:519	full factor design experimental	502:532	full factor design experimental along with RSM	502:547	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	12	8	theme	pectin	1783:1788	arg1	yields					1756:1761	the yields	1752:1761	the yields of pectin/low-ester pectin	1752:1788	Ultrasound treatment significantly improved the yields of pectin/low-ester pectin.					
35617886	8	9	theme	higher	1274:1279	arg1	values					1284:1289	higher DE values	1274:1289	higher DE values	1274:1289	Two DESs-extracted pectins exhibited higher DE values than HCl-extracted pectin.					
35617886	4	10	contain	had	717:719	arg2	weight					766:771	larger molecular weight	749:771	larger molecular weight	749:771	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	4	10	contain	had	717:719	arg2	yield					742:746	significantly higher yield	721:746	significantly higher yield	721:746	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	4	10	contain	had	717:719	arg2	particles					777:785	particles	777:785	particles	777:785	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	4	10	contain	had	717:719	arg1	pectins					709:715	Two DES-extracted pectins	691:715	Two DES-extracted pectins	691:715	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	5	11	theme	ultrasound	834:843	arg1	power					845:849	High intensity ultrasound power	819:849	High intensity ultrasound power	819:849	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	2	12	theme	factor	507:512	arg1	design					514:519	full factor design experimental	502:532	full factor design experimental along with RSM	502:547	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	3	13	theme	ultrasound	563:572	arg1	treatment					574:582	ultrasound treatment	563:582	ultrasound treatment	563:582	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	6	14	located	observed	1090:1097	arg1	pectins					1121:1127	two DESs-extracted pectins	1102:1127	two DESs-extracted pectins	1102:1127	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	6	14	located	observed	1090:1097	arg2	content					1028:1034	higher content	1021:1034	higher content of galacturonic acid (GalA) and larger HG region	1021:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	8	15	theme	HCl-extracted	1296:1308	arg1	pectin					1310:1315	HCl-extracted pectin	1296:1315	HCl-extracted pectin	1296:1315	Two DESs-extracted pectins exhibited higher DE values than HCl-extracted pectin.					
35617886	0	16	theme	mango	157:161	arg1	peels					163:167	mango peels	157:167	mango peels	157:167	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	5	17	theme	molecular	910:918	arg1	weight					920:925	molecular weight	910:925	molecular weight	910:925	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	14	18	dep	food	2163:2166	arg1	the					2159:2161	the	2159:2161	the	2159:2161	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	6	19	theme	higher	1021:1026	arg1	content					1028:1034	higher content	1021:1034	higher content of galacturonic acid (GalA) and larger HG region	1021:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	10	20	theme	viscosity	1494:1502	arg1	properties					1504:1513	higher viscosity properties	1487:1513	higher viscosity properties	1487:1513	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	4	21	theme	larger	749:754	arg1	weight					766:771	larger molecular weight	749:771	larger molecular weight	749:771	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	3	22	theme	physicochemical	642:656	arg1	properties					658:667	structural and physicochemical properties	627:667	structural and physicochemical properties of extracted pectins	627:688	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	22	theme	physicochemical	642:656	arg1	yield					620:624	extraction yield	609:624	extraction yield	609:624	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	0	23	theme	structural	89:98	arg1	properties					120:129	structural and physicochemical properties	89:129	structural and physicochemical properties of pectins extracted from mango peels	89:167	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	9	24	theme	Thermal	1318:1324	arg1	analysis					1326:1333	Thermal analysis	1318:1333	Thermal analysis	1318:1333	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	6	25	theme	compositions	987:998	arg1	analysis					1000:1007	Monosaccharide compositions analysis	972:1007	Monosaccharide compositions analysis	972:1007	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	10	26	theme	DESs-extracted	1524:1537	arg1	pectins					1539:1545	two DESs-extracted pectins	1520:1545	two DESs-extracted pectins	1520:1545	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	0	27	theme	physicochemical	104:118	arg1	properties					120:129	structural and physicochemical properties	89:129	structural and physicochemical properties of pectins extracted from mango peels	89:167	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	0	28	theme	deep	45:48	arg1	solvents					59:66	sonication-synergistic natural deep eutectic solvents	14:66	sonication-synergistic natural deep eutectic solvents	14:66	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	6	29	theme	HG	1075:1076	arg1	region					1078:1083	larger HG region	1068:1083	larger HG region	1068:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	14	30	theme	pharmaceutical	2172:2185	arg1	industry					2187:2194	pharmaceutical industry	2172:2194	pharmaceutical industry	2172:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	2	31	theme	betaine-citric	359:372	arg1	acid					374:377	betaine-citric acid	359:377	betaine-citric acid (Bet-CA)	359:386	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	31	theme	betaine-citric	359:372	arg1	Bet-CA					380:385	Bet-CA	380:385	Bet-CA	380:385	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	13	32	theme	pectins	1896:1902	arg1	viscosity					1851:1859	viscosity	1851:1859	viscosity	1851:1859	Additionally, ultrasound treatment remarkably decreased the viscosity and viscoelastic properties of the pectins extracted.					
35617886	13	32	theme	pectins	1896:1902	arg1	properties					1878:1887	viscoelastic properties	1865:1887	viscoelastic properties	1865:1887	Additionally, ultrasound treatment remarkably decreased the viscosity and viscoelastic properties of the pectins extracted.					
35617886	2	33	theme	choline	392:398	arg1	ChCl-MaA					421:428	ChCl-MaA	421:428	ChCl-MaA	421:428	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	33	theme	choline	392:398	arg1	acid					415:418	choline chloride-malic acid	392:418	choline chloride-malic acid (ChCl-MaA)	392:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	5	34	theme	High	819:822	arg1	power					845:849	High intensity ultrasound power	819:849	High intensity ultrasound power	819:849	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	0	35	theme	natural	37:43	arg1	solvents					59:66	sonication-synergistic natural deep eutectic solvents	14:66	sonication-synergistic natural deep eutectic solvents	14:66	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	9	36	theme	HCl-extracted	1374:1386	arg1	pectin					1388:1393	HCl-extracted pectin	1374:1393	HCl-extracted pectin	1374:1393	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	14	37	theme	pectins	2051:2057	arg1	conditions					2002:2011	extraction conditions	1991:2011	extraction conditions	1991:2011	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	14	37	theme	pectins	2051:2057	arg1	properties					2033:2042	physicochemical properties	2017:2042	physicochemical properties	2017:2042	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	6	38	theme	acid	1052:1055	arg1	content					1028:1034	higher content	1021:1034	higher content of galacturonic acid (GalA) and larger HG region	1021:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	14	39	theme	peel	2143:2146	arg1	pectins					2148:2154	mango peel pectins	2137:2154	mango peel pectins	2137:2154	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	11	40	theme	colloid	1632:1638	arg1	state					1640:1644	a colloid state	1630:1644	a colloid state	1630:1644	Moreover, it was found that HCl-extracted pectin was in a colloid state, while two DESs-extracted pectins or CP were in a flow state.					
35617886	0	41	theme	eutectic	50:57	arg1	solvents					59:66	sonication-synergistic natural deep eutectic solvents	14:66	sonication-synergistic natural deep eutectic solvents	14:66	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	13	42	dep	viscosity	1851:1859	arg1	the					1847:1849	the	1847:1849	the	1847:1849	Additionally, ultrasound treatment remarkably decreased the viscosity and viscoelastic properties of the pectins extracted.					
35617886	1	43	used	used	233:236	arg2	DESs					222:225	DESs	222:225	DESs	222:225	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	43	used	used	233:236	arg2	solvents					212:219	eco-friendly deep eutectic solvents	185:219	eco-friendly deep eutectic solvents (DESs)	185:226	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	43	used	used	233:236	arg2	agents					252:257	extracting agents	241:257	extracting agents for the first time	241:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	9	44	dep	analysis	1326:1333	arg1	results					1354:1360	results	1354:1360	results	1354:1360	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	10	45	theme	HCl-extracted	1462:1474	arg1	pectin					1476:1481	HCl-extracted pectin	1462:1481	HCl-extracted pectin	1462:1481	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	14	46	theme	physicochemical	2017:2031	arg1	properties					2033:2042	physicochemical properties	2017:2042	physicochemical properties	2017:2042	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	6	47	theme	DESs-extracted	1106:1119	arg1	pectins					1121:1127	two DESs-extracted pectins	1102:1127	two DESs-extracted pectins	1102:1127	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	3	48	theme	structural	627:636	arg1	properties					658:667	structural and physicochemical properties	627:667	structural and physicochemical properties of extracted pectins	627:688	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	48	theme	structural	627:636	arg1	yield					620:624	extraction yield	609:624	extraction yield	609:624	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	9	49	contain	had	1395:1397	arg1	pectin					1388:1393	HCl-extracted pectin	1374:1393	HCl-extracted pectin	1374:1393	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	9	49	contain	had	1395:1397	arg2	stability					1406:1414	better stability	1399:1414	better stability	1399:1414	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	9	50	theme	ChCl-MaA-extracted	1421:1438	arg1	pectin					1440:1445	ChCl-MaA-extracted pectin	1421:1445	ChCl-MaA-extracted pectin	1421:1445	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	3	51	contain	had	589:591	arg2	influence					596:604	an influence	593:604	an influence	593:604	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	51	contain	had	589:591	arg1	treatment					574:582	ultrasound treatment	563:582	ultrasound treatment	563:582	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	52	theme	pectins	682:688	arg1	properties					658:667	structural and physicochemical properties	627:667	structural and physicochemical properties of extracted pectins	627:688	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	52	theme	pectins	682:688	arg1	yield					620:624	extraction yield	609:624	extraction yield	609:624	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	2	53	theme	novel	328:332	arg1	acid					374:377	betaine-citric acid	359:377	betaine-citric acid (Bet-CA)	359:386	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	53	theme	novel	328:332	arg1	acid					415:418	choline chloride-malic acid	392:418	choline chloride-malic acid (ChCl-MaA)	392:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	53	theme	novel	328:332	arg1	solvents					340:347	Two novel green solvents	324:347	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA)	324:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	11	54	theme	flow	1696:1699	arg1	state					1701:1705	a flow state	1694:1705	a flow state	1694:1705	Moreover, it was found that HCl-extracted pectin was in a colloid state, while two DESs-extracted pectins or CP were in a flow state.					
35617886	14	55	theme	extraction	1991:2000	arg1	conditions					2002:2011	extraction conditions	1991:2011	extraction conditions	1991:2011	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	7	56	theme	infrared	1148:1155	arg1	spectra					1157:1163	infrared spectra	1148:1163	infrared spectra (FT-IR) of all pectins extracted	1148:1196	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	7	56	theme	infrared	1148:1155	arg1	FT-IR					1166:1170	FT-IR	1166:1170	FT-IR	1166:1170	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	12	57	theme	pectin/low-ester	1766:1781	arg1	pectin					1783:1788	pectin/low-ester pectin	1766:1788	pectin/low-ester pectin	1766:1788	Ultrasound treatment significantly improved the yields of pectin/low-ester pectin.					
35617886	14	58	theme	relationship	1970:1981	arg1	understanding					1949:1961	our understanding	1945:1961	our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry	1945:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	6	59	theme	Monosaccharide	972:985	arg1	compositions					987:998	Monosaccharide compositions	972:998	Monosaccharide compositions analysis	972:1007	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	8	60	theme	DESs-extracted	1241:1254	arg1	pectins					1256:1262	Two DESs-extracted pectins	1237:1262	Two DESs-extracted pectins	1237:1262	Two DESs-extracted pectins exhibited higher DE values than HCl-extracted pectin.					
35617886	13	61	theme	ultrasound	1805:1814	arg1	treatment					1816:1824	ultrasound treatment	1805:1824	ultrasound treatment	1805:1824	Additionally, ultrasound treatment remarkably decreased the viscosity and viscoelastic properties of the pectins extracted.					
35617886	0	62	theme	pectins	134:140	arg1	properties					120:129	structural and physicochemical properties	89:129	structural and physicochemical properties of pectins extracted from mango peels	89:167	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	1	63	theme	deep	198:201	arg1	agents					252:257	extracting agents	241:257	extracting agents for the first time	241:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	63	theme	deep	198:201	arg1	DESs					222:225	DESs	222:225	DESs	222:225	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	63	theme	deep	198:201	arg1	solvents					212:219	eco-friendly deep eutectic solvents	185:219	eco-friendly deep eutectic solvents (DESs)	185:226	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	5	64	theme	low-ester	873:881	arg1	pectins					883:889	low-ester pectins	873:889	low-ester pectins	873:889	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	2	65	theme	full	502:505	arg1	design					514:519	full factor design experimental	502:532	full factor design experimental along with RSM	502:547	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	1	66	theme	pectins	299:305	arg1	extraction					285:294	the extraction	281:294	the extraction of pectins from mango peel	281:321	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	4	67	dep	yield	742:746	arg1	size					787:790	size	787:790	size	787:790	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	7	68	with	similar	1203:1209	arg1	differences					1224:1234	slight differences	1217:1234	slight differences	1217:1234	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	6	69	theme	galacturonic	1039:1050	arg1	GalA					1058:1061	GalA	1058:1061	GalA	1058:1061	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	6	69	theme	galacturonic	1039:1050	arg1	acid					1052:1055	galacturonic acid	1039:1055	galacturonic acid (GalA)	1039:1062	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	5	70	dep	weight	920:925	arg1	size					941:944	size	941:944	size	941:944	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	5	70	dep	weight	920:925	arg1	the					906:908	the	906:908	the	906:908	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	4	71	theme	DES-extracted	695:707	arg1	pectins					709:715	Two DES-extracted pectins	691:715	Two DES-extracted pectins	691:715	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	7	72	theme	slight	1217:1222	arg1	differences					1224:1234	slight differences	1217:1234	slight differences	1217:1234	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	5	73	theme	intensity	824:832	arg1	power					845:849	High intensity ultrasound power	819:849	High intensity ultrasound power	819:849	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	5	74	theme	pectins	883:889	arg1	yield					864:868	the yield	860:868	the yield of low-ester pectins	860:889	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	2	75	theme	extraction	454:463	arg1	conditions					465:474	the extraction conditions	450:474	the extraction conditions	450:474	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	1	76	theme	mango	312:316	arg1	peel					318:321	mango peel	312:321	mango peel	312:321	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	0	77	from	effect	4:9	arg1	extraction					71:80	extraction	71:80	extraction	71:80	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	10	78	theme	higher	1487:1492	arg1	properties					1504:1513	higher viscosity properties	1487:1513	higher viscosity properties	1487:1513	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	5	79	theme	pectins	953:959	arg1	particles					931:939	particles	931:939	particles	931:939	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	5	79	theme	pectins	953:959	arg1	weight					920:925	molecular weight	910:925	molecular weight	910:925	High intensity ultrasound power enhanced the yield of low-ester pectins, but decreased the molecular weight and particles size of the pectins extracted.					
35617886	12	80	theme	Ultrasound	1708:1717	arg1	treatment					1719:1727	Ultrasound treatment	1708:1727	Ultrasound treatment	1708:1727	Ultrasound treatment significantly improved the yields of pectin/low-ester pectin.					
35617886	7	81	theme	pectins	1180:1186	arg1	spectra					1157:1163	infrared spectra	1148:1163	infrared spectra (FT-IR) of all pectins extracted	1148:1196	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	7	81	theme	pectins	1180:1186	arg1	FT-IR					1166:1170	FT-IR	1166:1170	FT-IR	1166:1170	Fourier transform infrared spectra (FT-IR) of all pectins extracted were similar, with slight differences.					
35617886	1	82	theme	eutectic	203:210	arg1	agents					252:257	extracting agents	241:257	extracting agents for the first time	241:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	82	theme	eutectic	203:210	arg1	DESs					222:225	DESs	222:225	DESs	222:225	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	82	theme	eutectic	203:210	arg1	solvents					212:219	eco-friendly deep eutectic solvents	185:219	eco-friendly deep eutectic solvents (DESs)	185:226	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	6	83	theme	region	1078:1083	arg1	content					1028:1034	higher content	1021:1034	higher content of galacturonic acid (GalA) and larger HG region	1021:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	4	84	theme	molecular	756:764	arg1	weight					766:771	larger molecular weight	749:771	larger molecular weight	749:771	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	9	85	theme	zeta	1339:1342	arg1	potential					1344:1352	zeta potential	1339:1352	zeta potential	1339:1352	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	14	86	theme	theoretical	2085:2095	arg1	basis					2097:2101	theoretical basis	2085:2101	theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry	2085:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	6	87	theme	larger	1068:1073	arg1	region					1078:1083	larger HG region	1068:1083	larger HG region	1068:1083	Monosaccharide compositions analysis showed that higher content of galacturonic acid (GalA) and larger HG region were observed in two DESs-extracted pectins.					
35617886	0	88	theme	sonication-synergistic	14:35	arg1	solvents					59:66	sonication-synergistic natural deep eutectic solvents	14:66	sonication-synergistic natural deep eutectic solvents	14:66	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	1	89	theme	first	267:271	arg1	time					273:276	the first time	263:276	the first time	263:276	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	2	90	theme	chloride-malic	400:413	arg1	ChCl-MaA					421:428	ChCl-MaA	421:428	ChCl-MaA	421:428	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	90	theme	chloride-malic	400:413	arg1	acid					415:418	choline chloride-malic acid	392:418	choline chloride-malic acid (ChCl-MaA)	392:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	10	91	theme	commercial	1550:1559	arg1	CP					1569:1570	CP	1569:1570	CP	1569:1570	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	10	91	theme	commercial	1550:1559	arg1	pectin					1561:1566	commercial pectin	1550:1566	commercial pectin (CP)	1550:1571	Additionally, HCl-extracted pectin had higher viscosity properties than two DESs-extracted pectins or commercial pectin (CP).					
35617886	3	92	theme	extraction	609:618	arg1	properties					658:667	structural and physicochemical properties	627:667	structural and physicochemical properties of extracted pectins	627:688	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	3	92	theme	extraction	609:618	arg1	yield					620:624	extraction yield	609:624	extraction yield	609:624	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	4	93	theme	higher	735:740	arg1	yield					742:746	significantly higher yield	721:746	significantly higher yield	721:746	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	1	94	from	peel	318:321	arg1	extraction					285:294	the extraction	281:294	the extraction of pectins from mango peel	281:321	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	1	94	from	peel	318:321	arg1	pectins					299:305	pectins	299:305	pectins from mango peel	299:321	In this study, eco-friendly deep eutectic solvents (DESs) were used as extracting agents for the first time in the extraction of pectins from mango peel.					
35617886	14	95	theme	pectins	2148:2154	arg1	application					2122:2132	the functional application	2107:2132	the functional application of mango peel pectins in the food and pharmaceutical industry	2107:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	4	96	theme	HCl-extracted	797:809	arg1	pectin					811:816	HCl-extracted pectin	797:816	HCl-extracted pectin	797:816	Two DES-extracted pectins had significantly higher yield, larger molecular weight and particles size than HCl-extracted pectin.					
35617886	0	97	theme	solvents	59:66	arg1	effect					4:9	The effect	0:9	The effect of sonication-synergistic natural deep eutectic solvents on extraction	0:80	The effect of sonication-synergistic natural deep eutectic solvents on extraction yield, structural and physicochemical properties of pectins extracted from mango peels.					
35617886	14	98	theme	mango	2137:2141	arg1	pectins					2148:2154	mango peel pectins	2137:2154	mango peel pectins	2137:2154	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	9	99	theme	better	1399:1404	arg1	stability					1406:1414	better stability	1399:1414	better stability	1399:1414	Thermal analysis and zeta potential results showed that HCl-extracted pectin had better stability than ChCl-MaA-extracted pectin.					
35617886	14	100	from	application	2122:2132	arg1	industry					2187:2194	pharmaceutical industry	2172:2194	pharmaceutical industry	2172:2194	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	14	100	from	application	2122:2132	arg1	food					2163:2166	food	2163:2166	food	2163:2166	The results were conducive to our understanding of the relationship between extraction conditions and physicochemical properties of the pectins extracted, which provides theoretical basis for the functional application of mango peel pectins in the food and pharmaceutical industry.					
35617886	8	101	theme	DE	1281:1282	arg1	values					1284:1289	higher DE values	1274:1289	higher DE values	1274:1289	Two DESs-extracted pectins exhibited higher DE values than HCl-extracted pectin.					
35617886	13	102	theme	viscoelastic	1865:1876	arg1	properties					1878:1887	viscoelastic properties	1865:1887	viscoelastic properties	1865:1887	Additionally, ultrasound treatment remarkably decreased the viscosity and viscoelastic properties of the pectins extracted.					
35617886	3	103	theme	extracted	672:680	arg1	pectins					682:688	extracted pectins	672:688	extracted pectins	672:688	In addition, ultrasound treatment also had an influence on extraction yield, structural and physicochemical properties of extracted pectins.					
35617886	2	104	theme	green	334:338	arg1	acid					374:377	betaine-citric acid	359:377	betaine-citric acid (Bet-CA)	359:386	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	104	theme	green	334:338	arg1	acid					415:418	choline chloride-malic acid	392:418	choline chloride-malic acid (ChCl-MaA)	392:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
35617886	2	104	theme	green	334:338	arg1	solvents					340:347	Two novel green solvents	324:347	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA)	324:429	Two novel green solvents including betaine-citric acid (Bet-CA) and choline chloride-malic acid (ChCl-MaA) were screened, and the extraction conditions were further optimized by full factor design experimental along with RSM.					
37298121	2	0	theme	energy	372:377	arg1	materials					387:395	electrochemical energy storage materials	356:395	electrochemical energy storage materials	356:395	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	6	1	theme	F	1196:1196	arg1	g-1					1198:1200	189.74 and 24.39 F g-1	1179:1200	g-1	1198:1200	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	6	2	theme	g-1	1110:1112	arg1	density					1095:1101	a current density	1085:1101	a current density of 1 A g-1	1085:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	3	theme	energy	2132:2137	arg1	devices					2147:2153	clean energy storage devices	2126:2153	clean energy storage devices	2126:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	6	4	from	density	1095:1101	arg1	g-1					1078:1080	2031.81 F g-1	1068:1080	2031.81 F g-1 at a current density of 1 A g-1	1068:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	5	theme	higher	1647:1652	arg1	performances					1654:1665	higher performances	1647:1665	higher performances observed for spinel Zn-ferrites nanocorals	1647:1708	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	6	theme	devices	2147:2153	arg1	production					2112:2121	the production	2108:2121	the production of clean energy storage devices	2108:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	3	7	theme	materials	610:618	arg1	formation					579:587	the formation	575:587	the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure)	575:687	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	1	8	theme	remarkable	207:216	arg1	properties					242:251	remarkable electronic and magnetic properties	207:251	remarkable electronic and magnetic properties	207:251	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	6	9	theme	higher	1031:1036	arg1	capacitance					1055:1065	a much higher maximum specific capacitance	1024:1065	a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1)	1024:1113	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	3	10	theme	most	539:542	arg1	procedures					556:565	most traditional procedures	539:565	most traditional procedures	539:565	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	9	11	theme	spinel	1680:1685	arg1	nanocorals					1699:1708	spinel Zn-ferrites nanocorals	1680:1708	spinel Zn-ferrites nanocorals	1680:1708	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	12	theme	oxygen	1941:1946	arg1	anions					1948:1953	the surrounding oxygen anions	1925:1953	the surrounding oxygen anions	1925:1953	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	13	theme	energy	1490:1495	arg1	value					1505:1509	a high energy density value	1483:1509	a high energy density value of 18.1 Wh kg-1	1483:1525	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	6	14	theme	A	1228:1228	arg1	density					1215:1221	a current density	1205:1221	a current density of 1 A	1205:1228	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	4	15	theme	cellulose	715:723	arg1	procedure					751:759	a cellulose nanofibers-mediated green procedure	713:759	a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites	713:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	6	16	theme	Zn-ferrites	979:989	arg1	supercapacitor					1002:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	4	17	theme	green	745:749	arg1	procedure					751:759	a cellulose nanofibers-mediated green procedure	713:759	a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites	713:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	6	18	theme	current	1207:1213	arg1	density					1215:1221	a current density	1205:1221	a current density of 1 A	1205:1228	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	0	19	theme	Nanocorals	82:91	arg1	Synthesis					42:50	Sustainable Cellulose Nanofibers-Mediated Synthesis	0:50	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.	0:133	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	6	20	theme	F	1076:1076	arg1	g-1					1078:1080	2031.81 F g-1	1068:1080	2031.81 F g-1 at a current density of 1 A g-1	1068:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	21	theme	unique	1738:1743	arg1	structure					1753:1761	their unique crystal structure	1732:1761	their unique crystal structure	1732:1761	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	22	theme	kg-1	1522:1525	arg1	value					1505:1509	a high energy density value	1483:1509	a high energy density value of 18.1 Wh kg-1	1483:1525	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	0	23	theme	High	97:100	arg1	Performances					102:113	High Performances	97:113	High Performances in Supercapacitors	97:132	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	1	24	theme	abundant	180:187	arg1	ferrites					142:149	Spinel ferrites	135:149	Spinel ferrites	135:149	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	24	theme	abundant	180:187	arg1	oxides					195:200	versatile, low-cost, and abundant metal oxides	155:200	versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications	155:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	4	25	theme	porous	790:795	arg1	nanocorals					797:806	controlled highly porous nanocorals	772:806	controlled highly porous nanocorals comprised of spinel Zn-ferrites	772:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	3	26	from	formation	579:587	arg1	terms					624:628	terms	624:628	terms of size, shape, composition, and/or crystalline structure	624:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	6	27	theme	specific	1046:1053	arg1	capacitance					1055:1065	a much higher maximum specific capacitance	1024:1065	a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1)	1024:1113	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	28	theme	electronic	1767:1776	arg1	configuration					1778:1790	electronic configuration	1767:1790	electronic configuration	1767:1790	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	2	29	theme	oxidation	419:427	arg1	states					429:434	their variable oxidation states	404:434	their variable oxidation states	404:434	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	9	30	theme	stabilization	1815:1827	arg1	energy					1829:1834	crystal field stabilization energy	1801:1834	crystal field stabilization energy	1801:1834	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	31	theme	kg-1	1558:1561	arg1	density					1538:1544	a power density	1530:1544	a power density of 2609.2 W kg-1	1530:1561	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	2	32	theme	possible	469:476	arg1	synthesis					478:486	possible synthesis	469:486	possible synthesis	469:486	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	0	33	theme	Sustainable	0:10	arg1	Synthesis					42:50	Sustainable Cellulose Nanofibers-Mediated Synthesis	0:50	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.	0:133	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	6	34	theme	A	1108:1108	arg1	g-1					1110:1112	1 A g-1	1106:1112	1 A g-1	1106:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	35	theme	crystal	1801:1807	arg1	energy					1829:1834	crystal field stabilization energy	1801:1834	crystal field stabilization energy	1801:1834	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	7	36	theme	excellent	1372:1380	arg1	stability					1392:1400	excellent long-term stability	1372:1400	excellent long-term stability	1372:1400	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	4	37	theme	controlled	772:781	arg1	nanocorals					797:806	controlled highly porous nanocorals	772:806	controlled highly porous nanocorals comprised of spinel Zn-ferrites	772:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	2	38	theme	environmental	441:453	arg1	toxicity					455:462	low environmental toxicity	437:462	low environmental toxicity	437:462	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	0	39	theme	Nanofibers-Mediated	22:40	arg1	Synthesis					42:50	Sustainable Cellulose Nanofibers-Mediated Synthesis	0:50	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.	0:133	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	1	40	theme	Spinel	135:140	arg1	ferrites					142:149	Spinel ferrites	135:149	Spinel ferrites	135:149	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	40	theme	Spinel	135:140	arg1	oxides					195:200	versatile, low-cost, and abundant metal oxides	155:200	versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications	155:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	7	41	theme	electrochemical	1321:1335	arg1	spectroscopy					1347:1358	electrochemical impedance spectroscopy	1321:1358	electrochemical impedance spectroscopy	1321:1358	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	2	42	theme	green	503:507	arg1	processing					518:527	simple green chemical processing	496:527	simple green chemical processing	496:527	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	3	43	theme	crystalline	666:676	arg1	structure					678:686	crystalline structure	666:686	crystalline structure	666:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	6	44	theme	current	1087:1093	arg1	density					1095:1101	a current density	1085:1101	a current density of 1 A g-1	1085:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	8	45	theme	A	1569:1569	arg1	g-1					1571:1573	1 A g-1	1567:1573	1 A g-1 in 2.0 mol L-1 KOH electrolyte	1567:1604	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	9	46	theme	interesting	2060:2070	arg1	supercapacitance					2011:2026	their final supercapacitance	1999:2026	their final supercapacitance	1999:2026	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	46	theme	interesting	2060:2070	arg1	property					2072:2079	a very interesting property	2053:2079	a very interesting property that could be explored for the production of clean energy storage devices	2053:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	47	theme	supercapacitor	1446:1459	arg1	device					1461:1466	an asymmetric supercapacitor device	1432:1466	an asymmetric supercapacitor device	1432:1466	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	2	48	theme	electrochemical	356:370	arg1	materials					387:395	electrochemical energy storage materials	356:395	electrochemical energy storage materials	356:395	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	4	49	theme	spinel	821:826	arg1	Zn-ferrites					828:838	spinel Zn-ferrites	821:838	spinel Zn-ferrites	821:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	2	50	theme	generation	342:351	arg1	part					325:328	part	325:328	part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis	325:486	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	1	51	with	oxides	195:200	arg1	properties					242:251	remarkable electronic and magnetic properties	207:251	remarkable electronic and magnetic properties	207:251	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	9	52	theme	electrostatic	1855:1867	arg1	repulsion					1869:1877	an electrostatic repulsion	1852:1877	an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions	1852:1953	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	3	53	theme	traditional	544:554	arg1	procedures					556:565	most traditional procedures	539:565	most traditional procedures	539:565	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	6	54	theme	spinel	972:977	arg1	supercapacitor					1002:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	6	55	theme	ZnO	1130:1132	arg1	counterparts					1134:1145	Fe2O3 and ZnO counterparts	1120:1145	Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1)	1120:1233	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	8	56	theme	KOH	1590:1592	arg1	electrolyte					1594:1604	2.0 mol L-1 KOH electrolyte	1578:1604	2.0 mol L-1 KOH electrolyte	1578:1604	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	9	57	theme	storage	2139:2145	arg1	devices					2147:2153	clean energy storage devices	2126:2153	clean energy storage devices	2126:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	2	58	theme	storage	379:385	arg1	materials					387:395	electrochemical energy storage materials	356:395	electrochemical energy storage materials	356:395	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	6	59	theme	Fe2O3	1120:1124	arg1	counterparts					1134:1145	Fe2O3 and ZnO counterparts	1120:1145	Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1)	1120:1233	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	60	theme	d	1891:1891	arg1	electrons					1893:1901	the d electrons	1887:1901	the d electrons	1887:1901	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	6	61	theme	g-1	1198:1200	arg1	approach					1169:1176	a similar approach	1159:1176	a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1)	1159:1233	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	6	61	theme	g-1	1198:1200	arg1	g-1					1230:1232	189.74 and 24.39 F g-1 at a current density of 1 A g-1	1179:1232	189.74 and 24.39 F g-1 at a current density of 1 A g-1	1179:1232	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	62	theme	clean	2126:2130	arg1	devices					2147:2153	clean energy storage devices	2126:2153	clean energy storage devices	2126:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	1	63	theme	metal	189:193	arg1	ferrites					142:149	Spinel ferrites	135:149	Spinel ferrites	135:149	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	63	theme	metal	189:193	arg1	oxides					195:200	versatile, low-cost, and abundant metal oxides	155:200	versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications	155:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	6	64	theme	24.39	1190:1194	arg1	g-1					1198:1200	189.74 and 24.39 F g-1	1179:1200	g-1	1198:1200	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	9	65	theme	p	1911:1911	arg1	orbitals					1913:1920	the p orbitals	1907:1920	the p orbitals of the surrounding oxygen anions	1907:1953	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	66	theme	crystal	1745:1751	arg1	structure					1753:1761	their unique crystal structure	1732:1761	their unique crystal structure	1732:1761	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	67	from	g-1	1571:1573	arg1	electrolyte					1594:1604	2.0 mol L-1 KOH electrolyte	1578:1604	2.0 mol L-1 KOH electrolyte	1578:1604	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	3	68	theme	controlled	599:608	arg1	materials					610:618	poorly controlled materials	592:618	poorly controlled materials	592:618	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	6	69	theme	maximum	1038:1044	arg1	capacitance					1055:1065	a much higher maximum specific capacitance	1024:1065	a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1)	1024:1113	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	6	70	theme	189.74	1179:1184	arg1	g-1					1198:1200	189.74 and 24.39 F g-1	1179:1200	g-1	1198:1200	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	5	71	theme	remarkable	862:871	arg1	applications					873:884	remarkable applications	862:884	remarkable applications	862:884	Then, they presented remarkable applications as electrodes in supercapacitors, which were thoroughly and critically discussed.					
37298121	0	72	from	Performances	102:113	arg1	Supercapacitors					118:132	Supercapacitors	118:132	Supercapacitors	118:132	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	9	73	theme	surrounding	1929:1939	arg1	anions					1948:1953	the surrounding oxygen anions	1925:1953	the surrounding oxygen anions	1925:1953	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	1	74	theme	magnetic	233:240	arg1	properties					242:251	remarkable electronic and magnetic properties	207:251	remarkable electronic and magnetic properties	207:251	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	9	75	theme	Zn-ferrites	1687:1697	arg1	nanocorals					1699:1708	spinel Zn-ferrites nanocorals	1680:1708	spinel Zn-ferrites nanocorals	1680:1708	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	76	theme	density	1497:1503	arg1	value					1505:1509	a high energy density value	1483:1509	a high energy density value of 18.1 Wh kg-1	1483:1525	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	9	77	theme	anions	1948:1953	arg1	orbitals					1913:1920	the p orbitals	1907:1920	the p orbitals of the surrounding oxygen anions	1907:1953	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	77	theme	anions	1948:1953	arg1	electrons					1893:1901	the d electrons	1887:1901	the d electrons	1887:1901	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	5	78	from	electrodes	889:898	arg1	supercapacitors					903:917	supercapacitors	903:917	supercapacitors	903:917	Then, they presented remarkable applications as electrodes in supercapacitors, which were thoroughly and critically discussed.					
37298121	6	79	theme	nanocorals	991:1000	arg1	supercapacitor					1002:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor	968:1015	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	3	80	theme	shape	639:643	arg1	terms					624:628	terms	624:628	terms of size, shape, composition, and/or crystalline structure	624:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	1	81	theme	versatile	155:163	arg1	ferrites					142:149	Spinel ferrites	135:149	Spinel ferrites	135:149	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	81	theme	versatile	155:163	arg1	oxides					195:200	versatile, low-cost, and abundant metal oxides	155:200	versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications	155:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	8	82	theme	Wh	1519:1520	arg1	kg-1					1522:1525	18.1 Wh kg-1	1514:1525	18.1 Wh kg-1	1514:1525	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	4	83	theme	nanofibers-mediated	725:743	arg1	procedure					751:759	a cellulose nanofibers-mediated green procedure	713:759	a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites	713:838	Thus, we report herein a cellulose nanofibers-mediated green procedure to prepare controlled highly porous nanocorals comprised of spinel Zn-ferrites.					
37298121	6	84	from	density	1215:1221	arg1	g-1					1198:1200	189.74 and 24.39 F g-1	1179:1200	g-1	1198:1200	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	3	85	theme	size	633:636	arg1	terms					624:628	terms	624:628	terms of size, shape, composition, and/or crystalline structure	624:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	1	86	theme	electronic	218:227	arg1	properties					242:251	remarkable electronic and magnetic properties	207:251	remarkable electronic and magnetic properties	207:251	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	87	theme	low-cost	166:173	arg1	ferrites					142:149	Spinel ferrites	135:149	Spinel ferrites	135:149	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	1	87	theme	low-cost	166:173	arg1	oxides					195:200	versatile, low-cost, and abundant metal oxides	155:200	versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications	155:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
37298121	6	88	dep	capacitance	1055:1065	arg1	g-1					1078:1080	2031.81 F g-1	1068:1080	2031.81 F g-1 at a current density of 1 A g-1	1068:1112	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	7	89	theme	long-term	1382:1390	arg1	stability					1392:1400	excellent long-term stability	1372:1400	excellent long-term stability	1372:1400	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	9	90	theme	energy	1976:1981	arg1	level					1967:1971	a level	1965:1971	a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices	1965:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	2	91	theme	chemical	509:516	arg1	processing					518:527	simple green chemical processing	496:527	simple green chemical processing	496:527	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	8	92	theme	power	1532:1536	arg1	density					1538:1544	a power density	1530:1544	a power density of 2609.2 W kg-1	1530:1561	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	8	93	theme	high	1485:1488	arg1	value					1505:1509	a high energy density value	1483:1509	a high energy density value of 18.1 Wh kg-1	1483:1525	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	9	94	theme	final	2005:2009	arg1	supercapacitance					2011:2026	their final supercapacitance	1999:2026	their final supercapacitance	1999:2026	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	9	94	theme	final	2005:2009	arg1	property					2072:2079	a very interesting property	2053:2079	a very interesting property that could be explored for the production of clean energy storage devices	2053:2153	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	8	95	theme	W	1556:1556	arg1	kg-1					1558:1561	2609.2 W kg-1	1549:1561	2609.2 W kg-1	1549:1561	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	2	96	theme	variable	410:417	arg1	states					429:434	their variable oxidation states	404:434	their variable oxidation states	404:434	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	0	97	theme	Cellulose	12:20	arg1	Synthesis					42:50	Sustainable Cellulose Nanofibers-Mediated Synthesis	0:50	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.	0:133	Sustainable Cellulose Nanofibers-Mediated Synthesis of Uniform Spinel Zn-Ferrites Nanocorals for High Performances in Supercapacitors.					
37298121	7	98	theme	impedance	1337:1345	arg1	spectroscopy					1347:1358	electrochemical impedance spectroscopy	1321:1358	electrochemical impedance spectroscopy	1321:1358	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	9	99	theme	field	1809:1813	arg1	energy					1829:1834	crystal field stabilization energy	1801:1834	crystal field stabilization energy	1801:1834	Based on our findings, we believe that higher performances observed for spinel Zn-ferrites nanocorals could be explained by their unique crystal structure and electronic configuration based on crystal field stabilization energy, which provides an electrostatic repulsion between the d electrons and the p orbitals of the surrounding oxygen anions, creating a level of energy that determines their final supercapacitance then evidenced, which is a very interesting property that could be explored for the production of clean energy storage devices.					
37298121	2	100	theme	low	437:439	arg1	toxicity					455:462	low environmental toxicity	437:462	low environmental toxicity	437:462	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	7	101	theme	galvanostatic	1282:1294	arg1	charging/discharging					1296:1315	galvanostatic charging/discharging	1282:1315	galvanostatic charging/discharging	1282:1315	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	2	102	theme	simple	496:501	arg1	processing					518:527	simple green chemical processing	496:527	simple green chemical processing	496:527	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	3	103	theme	composition	646:656	arg1	terms					624:628	terms	624:628	terms of size, shape, composition, and/or crystalline structure	624:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	6	104	theme	similar	1161:1167	arg1	approach					1169:1176	a similar approach	1159:1176	a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1)	1159:1233	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	6	104	theme	similar	1161:1167	arg1	g-1					1230:1232	189.74 and 24.39 F g-1 at a current density of 1 A g-1	1179:1232	189.74 and 24.39 F g-1 at a current density of 1 A g-1	1179:1232	The spinel Zn-ferrites nanocorals supercapacitor showed a much higher maximum specific capacitance (2031.81 F g-1 at a current density of 1 A g-1) than Fe2O3 and ZnO counterparts prepared by a similar approach (189.74 and 24.39 F g-1 at a current density of 1 A g-1).					
37298121	8	105	theme	2.0	1578:1580	arg1	mol					1582:1584	mol	1582:1584	mol	1582:1584	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	8	106	theme	asymmetric	1435:1444	arg1	device					1461:1466	an asymmetric supercapacitor device	1432:1466	an asymmetric supercapacitor device	1432:1466	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	8	107	theme	L-1	1586:1588	arg1	electrolyte					1594:1604	2.0 mol L-1 KOH electrolyte	1578:1604	2.0 mol L-1 KOH electrolyte	1578:1604	In addition, we manufactured an asymmetric supercapacitor device, which offered a high energy density value of 18.1 Wh kg-1 at a power density of 2609.2 W kg-1 (at 1 A g-1 in 2.0 mol L-1 KOH electrolyte).					
37298121	3	108	theme	structure	678:686	arg1	terms					624:628	terms	624:628	terms of size, shape, composition, and/or crystalline structure	624:686	However, most traditional procedures lead to the formation of poorly controlled materials (in terms of size, shape, composition, and/or crystalline structure).					
37298121	2	109	theme	next	337:340	arg1	generation					342:351	the next generation	333:351	the next generation of electrochemical energy storage materials	333:395	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	7	110	theme	cyclic	1240:1245	arg1	stability					1247:1255	Its cyclic stability	1236:1255	Its cyclic stability	1236:1255	Its cyclic stability was also scrutinized via galvanostatic charging/discharging and electrochemical impedance spectroscopy, indicating excellent long-term stability.					
37298121	2	111	theme	materials	387:395	arg1	generation					342:351	the next generation	333:351	the next generation of electrochemical energy storage materials	333:395	Among them, they have been considered part of the next generation of electrochemical energy storage materials due to their variable oxidation states, low environmental toxicity, and possible synthesis through simple green chemical processing.					
37298121	1	112	theme	several	265:271	arg1	applications					273:284	several applications	265:284	several applications	265:284	Spinel ferrites are versatile, low-cost, and abundant metal oxides with remarkable electronic and magnetic properties, which find several applications.					
35913650	8	0	theme	animal	1137:1142	arg1	study					1154:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	10	1	theme	HFD	1873:1875	arg1	group					1877:1881	HFD group	1873:1881	HFD group	1873:1881	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	1	2	theme	significant	267:277	arg1	impacts					286:292	significant health impacts	267:292	significant health impacts	267:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	8	3	theme	in-vivo	1145:1151	arg1	study					1154:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	6	4	theme	biological	895:904	arg1	activity					906:913	In-vitro biological activity	886:913	In-vitro biological activity	886:913	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	10	5	theme	various	1556:1562	arg1	proteins					1564:1571	various proteins	1556:1571	various proteins linked to carbohydrate and lipid metabolism	1556:1615	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	3	6	theme	uronic	493:498	arg1	sulfate					520:526	total sugar & sulfate	506:526	total sugar & sulfate	506:526	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	6	theme	uronic	493:498	arg1	acid					500:503	uronic acid	493:503	uronic acid	493:503	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	11	7	theme	property	1982:1989	arg1	elimination					1949:1959	elimination	1949:1959	elimination of bile acid binding property	1949:1989	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	3	8	theme	Proton	682:687	arg1	NMR					689:691	Proton NMR	682:691	Proton NMR	682:691	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	9	theme	&	518:518	arg1	sulfate					520:526	total sugar & sulfate	506:526	total sugar & sulfate	506:526	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	9	theme	&	518:518	arg1	acid					500:503	uronic acid	493:503	uronic acid	493:503	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	8	10	theme	ameliorative	1167:1178	arg1	effect					1180:1185	ameliorative effect	1167:1185	ameliorative effect	1167:1185	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	8	11	theme	plasma	1235:1240	arg1	insulin∼3.5↓					1242:1253	plasma insulin∼3.5↓	1235:1253	plasma insulin∼3.5↓	1235:1253	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	10	12	theme	Peroxisome	1747:1756	arg1	gamma					1791:1795	Peroxisome proliferator- activated receptor gamma	1747:1795	Peroxisome proliferator- activated receptor gamma (PPAR-γ)	1747:1804	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	12	theme	Peroxisome	1747:1756	arg1	PPAR-γ					1798:1803	PPAR-γ	1798:1803	PPAR-γ	1798:1803	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	9	13	theme	binding	1415:1421	arg1	properties					1423:1432	GAG-BA binding properties	1408:1432	GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol	1408:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	11	14	theme	potential	1908:1916	arg1	activity					1932:1939	potential hypolipidemic activity	1908:1939	potential hypolipidemic activity	1908:1939	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	7	15	theme	3T3L1	1070:1074	arg1	cells					1089:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	3	16	theme	chemical	530:537	arg1	characterization					539:554	chemical characterization	530:554	chemical characterization	530:554	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	9	17	theme	resultant	1434:1442	arg1	properties					1423:1432	GAG-BA binding properties	1408:1432	GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol	1408:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	8	18	theme	blood	1200:1204	arg1	sugar∼1.28↓					1206:1216	blood sugar∼1.28↓	1200:1216	blood sugar∼1.28↓	1200:1216	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	0	19	from	waste	82:86	arg1	potentiality					96:107	its potentiality	92:107	its potentiality in modulating obesity through in-vitro and in-vivo	92:158	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	0	19	from	waste	82:86	arg1	characterization					23:38	the partial characterization	11:38	the partial characterization of extracted glycosaminoglycans from fish waste	11:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	0	19	from	waste	82:86	arg1	glycosaminoglycans					53:70	extracted glycosaminoglycans	43:70	extracted glycosaminoglycans from fish waste	43:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	10	20	theme	acid	1633:1636	arg1	FAS					1648:1650	FAS	1648:1650	FAS	1648:1650	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	20	theme	acid	1633:1636	arg1	synthase					1638:1645	fatty acid synthase	1627:1645	fatty acid synthase (FAS)	1627:1651	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	8	21	theme	glucose	1265:1271	arg1	tolerance					1273:1281	improved glucose tolerance	1256:1281	improved glucose tolerance	1256:1281	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	3	22	dep	transform	641:649	arg1	&					680:680	&	680:680	transform infrared spectroscopy (FTIR) & Proton NMR	641:691	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	11	23	theme	associated	2064:2073	arg1	complications					2075:2087	its associated complications	2060:2087	its associated complications	2060:2087	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	10	24	theme	lipid	1600:1604	arg1	metabolism					1606:1615	lipid metabolism	1600:1615	lipid metabolism	1600:1615	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	25	theme	activated	1772:1780	arg1	gamma					1791:1795	Peroxisome proliferator- activated receptor gamma	1747:1795	Peroxisome proliferator- activated receptor gamma (PPAR-γ)	1747:1804	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	25	theme	activated	1772:1780	arg1	PPAR-γ					1798:1803	PPAR-γ	1798:1803	PPAR-γ	1798:1803	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	9	26	theme	elevated	1458:1465	arg1	triglyceride					1473:1484	elevated fecal triglyceride	1458:1484	elevated fecal triglyceride	1458:1484	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	6	27	theme	lipase	927:932	arg1	inhibition					934:943	good lipase inhibition	922:943	good lipase inhibition (IC50, 2.6 mg/mL)	922:961	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	8	28	theme	homeostatic	1288:1298	arg1	assessment					1306:1315	homeostatic model assessment	1288:1315	homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓)	1288:1355	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	1	29	located	found	236:240	arg2	Glycosaminoglycans					161:178	Glycosaminoglycans	161:178	Glycosaminoglycans (GAGs)	161:185	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	1	29	located	found	236:240	arg1	waste					254:258	the fish waste	245:258	the fish waste having significant health impacts	245:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	1	29	located	found	236:240	arg2	polysaccharides					201:215	polysaccharides	201:215	polysaccharides	201:215	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	3	30	theme	microscopy	612:621	arg1	techniques					580:589	techniques	580:589	techniques of scanning electron microscopy (SEM)	580:627	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	9	31	theme	triglyceride	1473:1484	arg1	removal					1447:1453	removal	1447:1453	removal of elevated fecal triglyceride and cholesterol	1447:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	3	32	theme	scanning	594:601	arg1	SEM					624:626	SEM	624:626	SEM	624:626	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	32	theme	scanning	594:601	arg1	microscopy					612:621	scanning electron microscopy	594:621	scanning electron microscopy (SEM)	594:627	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	9	33	theme	cholesterol	1490:1500	arg1	removal					1447:1453	removal	1447:1453	removal of elevated fecal triglyceride and cholesterol	1447:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	8	34	theme	insulin	1321:1327	arg1	resistance					1329:1338	insulin resistance	1321:1338	insulin resistance	1321:1338	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	6	35	theme	binding	977:983	arg1	properties					985:994	bile acid binding properties	967:994	bile acid binding properties (dose-dependent)	967:1011	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	0	36	from	Studies	0:6	arg1	potentiality					96:107	its potentiality	92:107	its potentiality in modulating obesity through in-vitro and in-vivo	92:158	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	0	36	from	Studies	0:6	arg1	characterization					23:38	the partial characterization	11:38	the partial characterization of extracted glycosaminoglycans from fish waste	11:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	9	37	theme	lowering	1523:1530	arg1	activity					1532:1539	its lipid lowering activity	1513:1539	its lipid lowering activity	1513:1539	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	6	38	theme	bile	967:970	arg1	properties					985:994	bile acid binding properties	967:994	bile acid binding properties (dose-dependent)	967:1011	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	2	39	theme	enzymatic	400:408	arg1	methods					410:416	chemical and enzymatic methods	387:416	chemical and enzymatic methods	387:416	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	0	40	from	characterization	23:38	arg1	waste					82:86	fish waste	77:86	fish waste	77:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	4	41	theme	probable	703:710	arg1	present					723:729	probable major GAGs present	703:729	probable major GAGs present	703:729	Further, probable major GAGs present was identified by enzymatic digestion.					
35913650	2	42	theme	chemical	387:394	arg1	methods					410:416	chemical and enzymatic methods	387:416	chemical and enzymatic methods	387:416	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	4	43	theme	GAGs	718:721	arg1	present					723:729	probable major GAGs present	703:729	probable major GAGs present	703:729	Further, probable major GAGs present was identified by enzymatic digestion.					
35913650	10	44	theme	density	1658:1664	arg1	lipoproteins					1666:1677	low density lipoproteins receptor (LDL-R)	1654:1694	low density lipoproteins receptor (LDL-R)	1654:1694	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	11	45	theme	acid	1969:1972	arg1	property					1982:1989	bile acid binding property	1964:1989	bile acid binding property	1964:1989	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	0	46	theme	extracted	43:51	arg1	glycosaminoglycans					53:70	extracted glycosaminoglycans	43:70	extracted glycosaminoglycans from fish waste	43:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	1	47	contain	having	260:265	arg2	impacts					286:292	significant health impacts	267:292	significant health impacts	267:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	1	47	contain	having	260:265	arg1	waste					254:258	the fish waste	245:258	the fish waste having significant health impacts	245:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	10	48	theme	glucose	1713:1719	arg1	GLUT4					1736:1740	GLUT4	1736:1740	GLUT4	1736:1740	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	48	theme	glucose	1713:1719	arg1	transporter-4					1721:1733	glucose transporter-4	1713:1733	glucose transporter-4 (GLUT4)	1713:1741	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	7	49	from	accumulation	1020:1031	arg1	cells					1089:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	10	50	theme	e-GAGs	1839:1844	arg1	treatment					1846:1854	e-GAGs treatment	1839:1854	e-GAGs treatment	1839:1854	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	1	51	theme	fish	249:252	arg1	waste					254:258	the fish waste	245:258	the fish waste having significant health impacts	245:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	8	52	theme	high	1124:1127	arg1	fat					1129:1131	The high fat	1120:1131	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	6	53	theme	good	922:925	arg1	inhibition					934:943	good lipase inhibition	922:943	good lipase inhibition (IC50, 2.6 mg/mL)	922:961	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	2	54	theme	mackerel	359:366	arg1	waste					373:377	mackerel fish waste	359:377	mackerel fish waste	359:377	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	9	55	theme	acid	1391:1394	arg1	elimination					1371:1381	elimination	1371:1381	elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol	1371:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	8	56	theme	fed	1133:1135	arg1	study					1154:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	10	57	theme	proteins	1564:1571	arg1	Regulation					1542:1551	Regulation	1542:1551	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ)	1542:1804	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	2	58	theme	present	302:308	arg1	study					310:314	the present study	298:314	the present study	298:314	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	1	59	theme	health	279:284	arg1	impacts					286:292	significant health impacts	267:292	significant health impacts	267:292	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	6	60	theme	In-vitro	886:893	arg1	activity					906:913	In-vitro biological activity	886:913	In-vitro biological activity	886:913	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	3	61	theme	sugar	512:516	arg1	sulfate					520:526	total sugar & sulfate	506:526	total sugar & sulfate	506:526	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	61	theme	sugar	512:516	arg1	acid					500:503	uronic acid	493:503	uronic acid	493:503	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	5	62	theme	in-vitro	856:863	arg1	studies					877:883	in-vitro and in-vivo studies	856:883	in-vitro and in-vivo studies	856:883	The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies.					
35913650	8	63	theme	lipid	1219:1223	arg1	profile↓					1225:1232	lipid profile↓	1219:1232	lipid profile↓	1219:1232	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	7	64	theme	preadipocyte	1076:1087	arg1	cells					1089:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	10	65	theme	proliferator-	1758:1770	arg1	gamma					1791:1795	Peroxisome proliferator- activated receptor gamma	1747:1795	Peroxisome proliferator- activated receptor gamma (PPAR-γ)	1747:1804	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	65	theme	proliferator-	1758:1770	arg1	PPAR-γ					1798:1803	PPAR-γ	1798:1803	PPAR-γ	1798:1803	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	9	66	theme	GAG-BA	1408:1413	arg1	properties					1423:1432	GAG-BA binding properties	1408:1432	GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol	1408:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	2	67	from	waste	373:377	arg1	GAGs					349:352	extract GAGs	341:352	extract GAGs from mackerel fish waste	341:377	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	7	68	theme	differentiated	1055:1068	arg1	cells					1089:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	5	69	theme	extracted	802:810	arg1	glycoconjugate					812:825	the extracted glycoconjugate	798:825	the extracted glycoconjugate	798:825	The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies.					
35913650	11	70	theme	specific	2020:2027	arg1	protein					2029:2035	the specific protein	2016:2035	the specific protein related to obesity and its associated complications	2016:2087	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	6	71	dep	inhibition	934:943	arg1	2.6 mg/mL					952:960	2.6 mg/mL	952:960	2.6 mg/mL	952:960	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	6	71	dep	inhibition	934:943	arg1	IC50					946:949	IC50	946:949	IC50	946:949	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	10	72	theme	fatty	1627:1631	arg1	FAS					1648:1650	FAS	1648:1650	FAS	1648:1650	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	72	theme	fatty	1627:1631	arg1	synthase					1638:1645	fatty acid synthase	1627:1645	fatty acid synthase (FAS)	1627:1651	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	11	73	theme	hypolipidemic	1918:1930	arg1	activity					1932:1939	potential hypolipidemic activity	1908:1939	potential hypolipidemic activity	1908:1939	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	1	74	theme	bioactive	191:199	arg1	Glycosaminoglycans					161:178	Glycosaminoglycans	161:178	Glycosaminoglycans (GAGs)	161:185	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	1	74	theme	bioactive	191:199	arg1	polysaccharides					201:215	polysaccharides	201:215	polysaccharides	201:215	Glycosaminoglycans (GAGs) are bioactive polysaccharides or glycoconjugates found in the fish waste having significant health impacts.					
35913650	11	75	theme	related	2037:2043	arg1	protein					2029:2035	the specific protein	2016:2035	the specific protein related to obesity and its associated complications	2016:2087	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	8	76	theme	improved	1256:1263	arg1	tolerance					1273:1281	improved glucose tolerance	1256:1281	improved glucose tolerance	1256:1281	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	7	77	theme	lowered	1033:1039	arg1	accumulation					1020:1031	Lipid accumulation lowered	1014:1039	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells	1014:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	10	78	theme	receptor	1782:1789	arg1	gamma					1791:1795	Peroxisome proliferator- activated receptor gamma	1747:1795	Peroxisome proliferator- activated receptor gamma (PPAR-γ)	1747:1804	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	78	theme	receptor	1782:1789	arg1	PPAR-γ					1798:1803	PPAR-γ	1798:1803	PPAR-γ	1798:1803	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	79	with	significant	1811:1821	arg1	treatment					1846:1854	e-GAGs treatment	1839:1854	e-GAGs treatment	1839:1854	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	7	80	theme	Lipid	1014:1018	arg1	accumulation					1020:1031	Lipid accumulation lowered	1014:1039	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells	1014:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	3	81	theme	electron	603:610	arg1	SEM					624:626	SEM	624:626	SEM	624:626	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	81	theme	electron	603:610	arg1	microscopy					612:621	scanning electron microscopy	594:621	scanning electron microscopy (SEM)	594:627	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	9	82	theme	fecal	1467:1471	arg1	triglyceride					1473:1484	elevated fecal triglyceride	1458:1484	elevated fecal triglyceride	1458:1484	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	0	83	from	potentiality	96:107	arg1	waste					82:86	fish waste	77:86	fish waste	77:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	0	84	theme	fish	77:80	arg1	waste					82:86	fish waste	77:86	fish waste	77:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	10	85	attach	linked	1573:1578	arg2	proteins					1564:1571	various proteins	1556:1571	various proteins linked to carbohydrate and lipid metabolism	1556:1615	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	85	attach	linked	1573:1578	arg1	carbohydrate					1583:1594	carbohydrate	1583:1594	carbohydrate	1583:1594	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	85	attach	linked	1573:1578	arg1	metabolism					1606:1615	lipid metabolism	1600:1615	lipid metabolism	1600:1615	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	11	86	theme	bile	1964:1967	arg1	property					1982:1989	bile acid binding property	1964:1989	bile acid binding property	1964:1989	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	5	87	theme	in-vivo	869:875	arg1	studies					877:883	in-vitro and in-vivo studies	856:883	in-vitro and in-vivo studies	856:883	The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies.					
35913650	8	88	theme	model	1300:1304	arg1	assessment					1306:1315	homeostatic model assessment	1288:1315	homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓)	1288:1355	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	10	89	dep	significant	1811:1821	arg1	p < 0.05					1824:1831	p < 0.05	1824:1831	p < 0.05	1824:1831	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	6	90	dep	properties	985:994	arg1	dose-dependent					997:1010	dose-dependent	997:1010	dose-dependent	997:1010	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	9	91	theme	lipid	1517:1521	arg1	activity					1532:1539	its lipid lowering activity	1513:1539	its lipid lowering activity	1513:1539	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	6	92	theme	acid	972:975	arg1	properties					985:994	bile acid binding properties	967:994	bile acid binding properties (dose-dependent)	967:1011	In-vitro biological activity showed good lipase inhibition (IC50, 2.6 mg/mL) and bile acid binding properties (dose-dependent).					
35913650	5	93	theme	glycoconjugate	812:825	arg1	potential					785:793	The biological potential	770:793	The biological potential of the extracted glycoconjugate	770:825	The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies.					
35913650	3	94	dep	composition	480:490	arg1	sulfate					520:526	total sugar & sulfate	506:526	total sugar & sulfate	506:526	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	94	dep	composition	480:490	arg1	acid					500:503	uronic acid	493:503	uronic acid	493:503	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	5	95	theme	biological	774:783	arg1	potential					785:793	The biological potential	770:793	The biological potential of the extracted glycoconjugate	770:825	The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies.					
35913650	10	96	dep	lipoproteins	1666:1677	arg1	LDL-R					1689:1693	LDL-R	1689:1693	LDL-R	1689:1693	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	10	96	dep	lipoproteins	1666:1677	arg1	receptor					1679:1686	receptor	1679:1686	low density lipoproteins receptor (LDL-R)	1654:1694	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	3	97	theme	extracted	432:440	arg1	GAGs					442:445	the extracted GAGs	428:445	the extracted GAGs (e-GAGs)	428:454	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	97	theme	extracted	432:440	arg1	e-GAGs					448:453	e-GAGs	448:453	e-GAGs	448:453	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	0	98	theme	partial	15:21	arg1	characterization					23:38	the partial characterization	11:38	the partial characterization of extracted glycosaminoglycans from fish waste	11:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	4	99	theme	major	712:716	arg1	present					723:729	probable major GAGs present	703:729	probable major GAGs present	703:729	Further, probable major GAGs present was identified by enzymatic digestion.					
35913650	10	100	theme	low	1654:1656	arg1	lipoproteins					1666:1677	low density lipoproteins receptor (LDL-R)	1654:1694	low density lipoproteins receptor (LDL-R)	1654:1694	Regulation of various proteins linked to carbohydrate and lipid metabolism including fatty acid synthase (FAS), low density lipoproteins receptor (LDL-R), 7α-hydroxylase, glucose transporter-4 (GLUT4) and Peroxisome proliferator- activated receptor gamma (PPAR-γ) were significant (p < 0.05) with e-GAGs treatment when compared to HFD group.					
35913650	0	101	theme	glycosaminoglycans	53:70	arg1	potentiality					96:107	its potentiality	92:107	its potentiality in modulating obesity through in-vitro and in-vivo	92:158	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	0	101	theme	glycosaminoglycans	53:70	arg1	characterization					23:38	the partial characterization	11:38	the partial characterization of extracted glycosaminoglycans from fish waste	11:86	Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.					
35913650	8	102	dep	assessment	1306:1315	arg1	HOMA-IR					1341:1347	HOMA-IR	1341:1347	HOMA-IR	1341:1347	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	8	102	dep	assessment	1306:1315	arg1	∼3.0↓					1350:1354	∼3.0↓	1350:1354	∼3.0↓	1350:1354	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	9	103	from	removal	1447:1453	arg1	resultant					1434:1442	resultant	1434:1442	resultant	1434:1442	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	7	104	theme	e-GAGs	1048:1053	arg1	cells					1089:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	the e-GAGs differentiated 3T3L1 preadipocyte cells	1044:1093	Lipid accumulation lowered in the e-GAGs differentiated 3T3L1 preadipocyte cells have also been observed.					
35913650	3	105	theme	infrared	651:658	arg1	FTIR					674:677	FTIR	674:677	FTIR	674:677	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	105	theme	infrared	651:658	arg1	spectroscopy					660:671	infrared spectroscopy	651:671	infrared spectroscopy (FTIR)	651:678	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	2	106	theme	extract	341:347	arg1	GAGs					349:352	extract GAGs	341:352	extract GAGs from mackerel fish waste	341:377	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	9	107	from	resultant	1434:1442	arg1	removal					1447:1453	removal	1447:1453	removal of elevated fecal triglyceride and cholesterol	1447:1500	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	11	108	theme	binding	1974:1980	arg1	property					1982:1989	bile acid binding property	1964:1989	bile acid binding property	1964:1989	Thus, the e-GAGs showed potential hypolipidemic activity through elimination of bile acid binding property together with regulating the specific protein related to obesity and its associated complications.					
35913650	4	109	theme	enzymatic	749:757	arg1	digestion					759:767	enzymatic digestion	749:767	enzymatic digestion	749:767	Further, probable major GAGs present was identified by enzymatic digestion.					
35913650	2	110	theme	fish	368:371	arg1	waste					373:377	mackerel fish waste	359:377	mackerel fish waste	359:377	In the present study it has been attempted to extract GAGs from mackerel fish waste through chemical and enzymatic methods.					
35913650	8	111	theme	fat	1129:1131	arg1	study					1154:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study	1120:1158	The high fat fed animal (in-vivo) study showed ameliorative effect via reducing blood sugar∼1.28↓, lipid profile↓, plasma insulin∼3.5↓, improved glucose tolerance, and homeostatic model assessment for insulin resistance (HOMA-IR, ∼3.0↓).					
35913650	3	112	theme	total	506:510	arg1	sulfate					520:526	total sugar & sulfate	506:526	total sugar & sulfate	506:526	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	3	112	theme	total	506:510	arg1	acid					500:503	uronic acid	493:503	uronic acid	493:503	Further, the extracted GAGs (e-GAGs) were analyzed for their composition (uronic acid, total sugar & sulfate), chemical characterization was carried out through techniques of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) & Proton NMR.					
35913650	9	113	theme	bile	1386:1389	arg1	BA					1397:1398	BA	1397:1398	BA	1397:1398	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
35913650	9	113	theme	bile	1386:1389	arg1	acid					1391:1394	bile acid	1386:1394	bile acid (BA)	1386:1399	Furthermore, elimination of bile acid (BA) due to GAG-BA binding properties resultant in removal of elevated fecal triglyceride and cholesterol suggesting its lipid lowering activity.					
36771117	2	0	theme	residues	325:332	arg1	composition					304:314	the chemical composition	291:314	the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2	291:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	1	theme	Cellic	572:577	arg1	CTec2					579:583	an industrial cellulase Cellic CTec2	548:583	an industrial cellulase Cellic CTec2	548:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	4	2	theme	apricot	1149:1155	arg1	seeds					1157:1161	the apricot seeds shells and the walnut shells	1145:1190	seeds	1157:1161	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	7	3	theme	technologies	1593:1604	arg1	use					1542:1544	the use	1538:1544	the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials)	1538:1859	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	4	theme	work	244:247	arg1	goal					223:226	The goal	219:226	The goal of the research work	219:247	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	5	with	pretreatment	392:403	arg1	NaOH					410:413	NaOH	410:413	NaOH	410:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	5	with	pretreatment	392:403	arg1	application					533:543	the application	529:543	the application of an industrial cellulase Cellic CTec2	529:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	7	6	theme	affordable	1573:1582	arg1	technologies					1593:1604	inexpensive, simple and affordable chemical technologies	1549:1604	inexpensive, simple and affordable chemical technologies	1549:1604	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	1	7	theme	potential	162:170	arg1	material					182:189	a potential renewable material	160:189	a potential renewable material for biorefinery in Ukraine	160:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	7	theme	potential	162:170	arg1	shells					150:155	walnut shells	143:155	walnut shells	143:155	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	7	theme	potential	162:170	arg1	shells					132:137	apricot seeds shells	118:137	apricot seeds shells	118:137	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	4	8	dep	seeds	1157:1161	arg1	shells					1163:1168	shells	1163:1168	shells	1163:1168	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	2	9	from	biomass	339:345	arg1	composition					304:314	the chemical composition	291:314	the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2	291:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	9	from	biomass	339:345	arg1	residues					325:332	solid residues	319:332	solid residues from biomass	319:345	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	10	theme	polysaccharides	882:896	arg1	bioconversion					865:877	the bioconversion	861:877	the bioconversion of polysaccharides to sugars	861:906	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	7	11	theme	material	1771:1778	arg1	dependency					1789:1798	material external dependency	1771:1798	material external dependency	1771:1798	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	4	12	theme	glucose	978:984	arg1	yield					986:990	glucose yield	978:990	glucose yield	978:990	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	13	from	terms	969:973	arg1	pretreatment					922:933	The alkaline pretreatment	909:933	The alkaline pretreatment	909:933	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	13	from	terms	969:973	arg1	efficient					956:964	efficient	956:964	efficient	956:964	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	7	14	theme	energy	1760:1765	arg1	amount					1662:1667	the amount	1658:1667	the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials)	1658:1859	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	14	theme	energy	1760:1765	arg1	pollution					1686:1694	environmental pollution	1672:1694	environmental pollution (compared to the usual disposal practice of direct burning)	1672:1754	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	14	theme	energy	1760:1765	arg1	energy					1760:1765	energy	1760:1765	energy	1760:1765	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	15	theme	industrial	551:560	arg1	CTec2					579:583	an industrial cellulase Cellic CTec2	548:583	an industrial cellulase Cellic CTec2	548:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	4	16	from	efficient	956:964	arg1	comparison					995:1004	comparison	995:1004	comparison with that of acid and steam explosion	995:1042	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	16	from	efficient	956:964	arg1	terms					969:973	terms	969:973	terms of glucose yield	969:990	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	1	17	theme	apricot	118:124	arg1	shells					132:137	apricot seeds shells	118:137	apricot seeds shells	118:137	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	17	theme	apricot	118:124	arg1	shells					150:155	walnut shells	143:155	walnut shells	143:155	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	17	theme	apricot	118:124	arg1	material					182:189	a potential renewable material	160:189	a potential renewable material for biorefinery in Ukraine	160:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	2	18	theme	sugars	471:476	arg1	pretreatment					438:449	a steam explosion pretreatment	420:449	a steam explosion pretreatment	420:449	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	18	theme	sugars	471:476	arg1	H2SO4					376:380	H2SO4	376:380	H2SO4	376:380	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	18	theme	sugars	471:476	arg1	pretreatment					392:403	alkaline pretreatment	383:403	alkaline pretreatment with NaOH	383:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	18	theme	sugars	471:476	arg1	recovery					459:466	the recovery	455:466	the recovery of sugars and lignin after further enzymatic hydrolysis	455:522	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	19	dep	lignin	688:693	arg1	%					701:701	44.55%	696:701	44.55%	696:701	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	19	dep	lignin	688:693	arg1	%					712:712	44.63%	707:712	44.63%	707:712	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	20	theme	seeds	594:598	arg1	shells					600:605	Apricot seeds shells	586:605	Apricot seeds shells	586:605	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	6	21	from	amount	1362:1367	arg1	solids					1386:1391	the solids	1382:1391	the solids	1382:1391	The amount of lignin in the solids interferes with the efficiency of enzymatic hydrolysis.					
36771117	7	22	theme	shells	1523:1528	arg1	utilization					1508:1518	the efficient and perspective utilization	1478:1518	the efficient and perspective utilization of shells	1478:1528	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	4	23	from	shells	1185:1190	arg1	solids					1133:1138	the solids	1129:1138	the solids from the apricot seeds shells and the walnut shells	1129:1190	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	0	24	theme	Lignin	67:72	arg1	Sources					74:80	Lignin Sources	67:80	Lignin Sources	67:80	Apricot Seed Shells and Walnut Shells as Unconventional Sugars and Lignin Sources.					
36771117	2	25	with	recovery	459:466	arg1	NaOH					410:413	NaOH	410:413	NaOH	410:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	25	with	recovery	459:466	arg1	application					533:543	the application	529:543	the application of an industrial cellulase Cellic CTec2	529:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	1	26	theme	walnut	143:148	arg1	material					182:189	a potential renewable material	160:189	a potential renewable material for biorefinery in Ukraine	160:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	26	theme	walnut	143:148	arg1	shells					150:155	walnut shells	143:155	walnut shells	143:155	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	26	theme	walnut	143:148	arg1	shells					132:137	apricot seeds shells	118:137	apricot seeds shells	118:137	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	2	27	theme	further	495:501	arg1	hydrolysis					513:522	further enzymatic hydrolysis	495:522	further enzymatic hydrolysis	495:522	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	5	28	theme	apricot	1302:1308	arg1	shells					1315:1320	apricot seed shells	1302:1320	apricot seed shells submitted to the acid pretreatment	1302:1355	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	4	29	theme	cellulose	1086:1094	arg1	conversions					1071:1081	the maximum enzymatic conversions	1049:1081	the maximum enzymatic conversions of cellulose reached	1049:1102	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	29	theme	cellulose	1086:1094	arg1	%					1113:1113	99.7%	1109:1113	99.7%	1109:1113	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	7	30	theme	burning	1747:1753	arg1	practice					1728:1735	the usual disposal practice	1709:1735	the usual disposal practice of direct burning	1709:1753	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	31	theme	lignin	482:487	arg1	pretreatment					438:449	a steam explosion pretreatment	420:449	a steam explosion pretreatment	420:449	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	31	theme	lignin	482:487	arg1	H2SO4					376:380	H2SO4	376:380	H2SO4	376:380	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	31	theme	lignin	482:487	arg1	pretreatment					392:403	alkaline pretreatment	383:403	alkaline pretreatment with NaOH	383:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	31	theme	lignin	482:487	arg1	recovery					459:466	the recovery	455:466	the recovery of sugars and lignin after further enzymatic hydrolysis	455:522	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	6	32	theme	enzymatic	1427:1435	arg1	hydrolysis					1437:1446	enzymatic hydrolysis	1427:1446	enzymatic hydrolysis	1427:1446	The amount of lignin in the solids interferes with the efficiency of enzymatic hydrolysis.					
36771117	4	33	theme	maximum	1053:1059	arg1	conversions					1071:1081	the maximum enzymatic conversions	1049:1081	the maximum enzymatic conversions of cellulose reached	1049:1102	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	33	theme	maximum	1053:1059	arg1	%					1113:1113	99.7%	1109:1113	99.7%	1109:1113	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	0	34	theme	Apricot	0:6	arg1	Shells					13:18	Apricot Seed Shells	0:18	Apricot Seed Shells	0:18	Apricot Seed Shells and Walnut Shells as Unconventional Sugars and Lignin Sources.					
36771117	7	35	theme	disposal	1719:1726	arg1	practice					1728:1735	the usual disposal practice	1709:1735	the usual disposal practice of direct burning	1709:1753	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	4	36	theme	alkaline	913:920	arg1	pretreatment					922:933	The alkaline pretreatment	909:933	The alkaline pretreatment	909:933	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	36	theme	alkaline	913:920	arg1	efficient					956:964	efficient	956:964	efficient	956:964	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	5	37	theme	acid	1339:1342	arg1	pretreatment					1344:1355	the acid pretreatment	1335:1355	the acid pretreatment	1335:1355	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	2	38	theme	alkaline	383:390	arg1	pretreatment					392:403	alkaline pretreatment	383:403	alkaline pretreatment with NaOH	383:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	0	39	theme	Walnut	24:29	arg1	Shells					31:36	Walnut Shells	24:36	Walnut Shells	24:36	Apricot Seed Shells and Walnut Shells as Unconventional Sugars and Lignin Sources.					
36771117	5	40	from	amount	1219:1224	arg1	solid					1258:1262	solid	1258:1262	solid	1258:1262	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	2	41	theme	explosion	428:436	arg1	pretreatment					438:449	a steam explosion pretreatment	420:449	a steam explosion pretreatment	420:449	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	5	42	theme	shells	1315:1320	arg1	processing					1288:1297	the processing	1284:1297	the processing of apricot seed shells submitted to the acid pretreatment	1284:1355	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	2	43	theme	solid	319:323	arg1	residues					325:332	solid residues	319:332	solid residues from biomass	319:345	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	7	44	theme	pollution	1686:1694	arg1	amount					1662:1667	the amount	1658:1667	the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials)	1658:1859	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	44	theme	pollution	1686:1694	arg1	pollution					1686:1694	environmental pollution	1672:1694	environmental pollution (compared to the usual disposal practice of direct burning)	1672:1754	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	44	theme	pollution	1686:1694	arg1	energy					1760:1765	energy	1760:1765	energy	1760:1765	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	5	45	theme	lignin	1229:1234	arg1	%					1239:1239	82%	1237:1239	82%	1237:1239	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	5	45	theme	lignin	1229:1234	arg1	amount					1219:1224	The maximum amount	1207:1224	The maximum amount of lignin (82%) in the residual solid	1207:1262	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	5	45	theme	lignin	1229:1234	arg1	lignin					1229:1234	lignin	1229:1234	lignin (82%)	1229:1240	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	2	46	with	pretreatment	358:369	arg1	pretreatment					392:403	alkaline pretreatment	383:403	alkaline pretreatment with NaOH	383:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	46	with	pretreatment	358:369	arg1	H2SO4					376:380	H2SO4	376:380	H2SO4	376:380	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	46	with	pretreatment	358:369	arg1	pretreatment					438:449	a steam explosion pretreatment	420:449	a steam explosion pretreatment	420:449	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	7	47	theme	value-added	1617:1627	arg1	products					1629:1636	value-added products	1617:1636	value-added products	1617:1636	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	3	48	dep	lots	636:639	arg1	%					670:670	35.01 and 24.19%	655:670	35.01 and 24.19%	655:670	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	2	49	with	H2SO4	376:380	arg1	NaOH					410:413	NaOH	410:413	NaOH	410:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	49	with	H2SO4	376:380	arg1	application					533:543	the application	529:543	the application of an industrial cellulase Cellic CTec2	529:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	50	theme	CTec2	579:583	arg1	application					533:543	the application	529:543	the application of an industrial cellulase Cellic CTec2	529:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	51	from	composition	304:314	arg1	biomass					339:345	biomass	339:345	biomass	339:345	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	4	52	theme	walnut	1178:1183	arg1	shells					1185:1190	the walnut shells	1174:1190	the walnut shells	1174:1190	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	7	53	theme	renewable	1830:1838	arg1	materials					1850:1858	these renewable, low-cost materials	1824:1858	these renewable, low-cost materials	1824:1858	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	54	theme	cellulase	562:570	arg1	CTec2					579:583	an industrial cellulase Cellic CTec2	548:583	an industrial cellulase Cellic CTec2	548:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	55	theme	bioconversion	865:877	arg1	efficiency					847:856	the efficiency	843:856	the efficiency of the bioconversion of polysaccharides to sugars	843:906	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	4	56	from	comparison	995:1004	arg1	pretreatment					922:933	The alkaline pretreatment	909:933	The alkaline pretreatment	909:933	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	56	from	comparison	995:1004	arg1	efficient					956:964	efficient	956:964	efficient	956:964	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	1	57	theme	renewable	172:180	arg1	material					182:189	a potential renewable material	160:189	a potential renewable material for biorefinery in Ukraine	160:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	57	theme	renewable	172:180	arg1	shells					150:155	walnut shells	143:155	walnut shells	143:155	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	57	theme	renewable	172:180	arg1	shells					132:137	apricot seeds shells	118:137	apricot seeds shells	118:137	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	4	58	theme	yield	986:990	arg1	terms					969:973	terms	969:973	terms of glucose yield	969:990	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	7	59	theme	external	1780:1787	arg1	dependency					1789:1798	material external dependency	1771:1798	material external dependency	1771:1798	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	60	theme	enzymatic	503:511	arg1	hydrolysis					513:522	further enzymatic hydrolysis	495:522	further enzymatic hydrolysis	495:522	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	61	dep	hemicelluloses	730:743	arg1	%					751:751	10.77%	746:751	10.77%	746:751	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	61	dep	hemicelluloses	730:743	arg1	%					762:762	26.68%	757:762	26.68%	757:762	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	7	62	theme	simple	1562:1567	arg1	technologies					1593:1604	inexpensive, simple and affordable chemical technologies	1549:1604	inexpensive, simple and affordable chemical technologies	1549:1604	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	63	theme	research	235:242	arg1	work					244:247	the research work	231:247	the research work	231:247	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	1	64	from	material	182:189	arg1	Ukraine					210:216	Ukraine	210:216	Ukraine	210:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	7	65	theme	inexpensive	1549:1559	arg1	technologies					1593:1604	inexpensive, simple and affordable chemical technologies	1549:1604	inexpensive, simple and affordable chemical technologies	1549:1604	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	66	dep	renewable	1830:1838	arg1	low-cost					1841:1848	low-cost	1841:1848	low-cost	1841:1848	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	4	67	theme	acid	1019:1022	arg1	explosion					1034:1042	acid and steam explosion	1019:1042	explosion	1034:1042	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	3	68	theme	Apricot	586:592	arg1	shells					600:605	Apricot seeds shells	586:605	Apricot seeds shells	586:605	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	6	69	theme	lignin	1372:1377	arg1	lignin					1372:1377	lignin	1372:1377	lignin	1372:1377	The amount of lignin in the solids interferes with the efficiency of enzymatic hydrolysis.					
36771117	6	69	theme	lignin	1372:1377	arg1	amount					1362:1367	The amount	1358:1367	The amount of lignin in the solids	1358:1391	The amount of lignin in the solids interferes with the efficiency of enzymatic hydrolysis.					
36771117	1	70	theme	seeds	126:130	arg1	shells					132:137	apricot seeds shells	118:137	apricot seeds shells	118:137	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	70	theme	seeds	126:130	arg1	shells					150:155	walnut shells	143:155	walnut shells	143:155	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	1	70	theme	seeds	126:130	arg1	material					182:189	a potential renewable material	160:189	a potential renewable material for biorefinery in Ukraine	160:216	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	4	71	theme	steam	1028:1032	arg1	explosion					1034:1042	acid and steam explosion	1019:1042	explosion	1034:1042	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	2	72	with	pretreatment	438:449	arg1	NaOH					410:413	NaOH	410:413	NaOH	410:413	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	2	72	with	pretreatment	438:449	arg1	application					533:543	the application	529:543	the application of an industrial cellulase Cellic CTec2	529:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	7	73	theme	chemical	1584:1591	arg1	technologies					1593:1604	inexpensive, simple and affordable chemical technologies	1549:1604	inexpensive, simple and affordable chemical technologies	1549:1604	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	74	theme	direct	1740:1745	arg1	burning					1747:1753	direct burning	1740:1753	direct burning	1740:1753	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	5	75	theme	seed	1310:1313	arg1	shells					1315:1320	apricot seed shells	1302:1320	apricot seed shells submitted to the acid pretreatment	1302:1355	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	6	76	theme	hydrolysis	1437:1446	arg1	efficiency					1413:1422	the efficiency	1409:1422	the efficiency of enzymatic hydrolysis	1409:1446	The amount of lignin in the solids interferes with the efficiency of enzymatic hydrolysis.					
36771117	7	77	theme	perspective	1496:1506	arg1	utilization					1508:1518	the efficient and perspective utilization	1478:1518	the efficient and perspective utilization of shells	1478:1528	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	78	dep	pollution	1686:1694	arg1	compared					1697:1704	compared	1697:1704	compared to the usual disposal practice of direct burning	1697:1753	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	4	79	from	seeds	1157:1161	arg1	solids					1133:1138	the solids	1129:1138	the solids from the apricot seeds shells and the walnut shells	1129:1190	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	80	theme	enzymatic	1061:1069	arg1	conversions					1071:1081	the maximum enzymatic conversions	1049:1081	the maximum enzymatic conversions of cellulose reached	1049:1102	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	4	80	theme	enzymatic	1061:1069	arg1	%					1113:1113	99.7%	1109:1113	99.7%	1109:1113	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	0	81	theme	Seed	8:11	arg1	Shells					13:18	Apricot Seed Shells	0:18	Apricot Seed Shells	0:18	Apricot Seed Shells and Walnut Shells as Unconventional Sugars and Lignin Sources.					
36771117	7	82	theme	usual	1713:1717	arg1	practice					1728:1735	the usual disposal practice	1709:1735	the usual disposal practice of direct burning	1709:1753	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	83	theme	efficient	1482:1490	arg1	utilization					1508:1518	the efficient and perspective utilization	1478:1518	the efficient and perspective utilization of shells	1478:1528	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	84	theme	acid	353:356	arg1	pretreatment					358:369	acid pretreatment	353:369	acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2	353:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	85	dep	extractives	784:794	arg1	%					801:801	9.97%	797:801	9.97%	797:801	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	85	dep	extractives	784:794	arg1	%					812:812	11.41%	807:812	11.41%	807:812	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	1	86	theme	present	87:93	arg1	study					95:99	The present study	83:99	The present study	83:99	The present study focuses on using apricot seeds shells and walnut shells as a potential renewable material for biorefinery in Ukraine.					
36771117	4	87	with	comparison	995:1004	arg1	that					1011:1014	that	1011:1014	that	1011:1014	The alkaline pretreatment was found to be more efficient in terms of glucose yield in comparison with that of acid and steam explosion, and the maximum enzymatic conversions of cellulose reached were 99.7% and 94.6% for the solids from the apricot seeds shells and the walnut shells, respectively.					
36771117	3	88	theme	walnut	611:616	arg1	shells					618:623	walnut shells	611:623	walnut shells	611:623	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	5	89	theme	maximum	1211:1217	arg1	%					1239:1239	82%	1237:1239	82%	1237:1239	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	5	89	theme	maximum	1211:1217	arg1	amount					1219:1224	The maximum amount	1207:1224	The maximum amount of lignin (82%) in the residual solid	1207:1262	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	5	89	theme	maximum	1211:1217	arg1	lignin					1229:1234	lignin	1229:1234	lignin (82%)	1229:1240	The maximum amount of lignin (82%) in the residual solid was obtained during the processing of apricot seed shells submitted to the acid pretreatment.					
36771117	0	90	theme	Unconventional	41:54	arg1	Sugars					56:61	Unconventional Sugars	41:61	Unconventional Sugars	41:61	Apricot Seed Shells and Walnut Shells as Unconventional Sugars and Lignin Sources.					
36771117	7	91	theme	environmental	1672:1684	arg1	pollution					1686:1694	environmental pollution	1672:1694	environmental pollution (compared to the usual disposal practice of direct burning)	1672:1754	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	92	theme	steam	422:426	arg1	pretreatment					438:449	a steam explosion pretreatment	420:449	a steam explosion pretreatment	420:449	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	3	93	theme	cellulose	644:652	arg1	lignin					688:693	lignin	688:693	lignin (44.55% and 44.63%, respectively)	688:727	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	93	theme	cellulose	644:652	arg1	hemicelluloses					730:743	hemicelluloses	730:743	hemicelluloses (10.77% and 26.68%, respectively)	730:777	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	93	theme	cellulose	644:652	arg1	cellulose					644:652	cellulose	644:652	cellulose	644:652	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	93	theme	cellulose	644:652	arg1	lots					636:639	lots	636:639	lots of cellulose (35.01 and 24.19%, respectively)	636:685	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	3	93	theme	cellulose	644:652	arg1	extractives					784:794	extractives	784:794	extractives (9.97% and 11.41%, respectively)	784:827	Apricot seeds shells and walnut shells consist of lots of cellulose (35.01 and 24.19%, respectively), lignin (44.55% and 44.63%, respectively), hemicelluloses (10.77% and 26.68%, respectively), and extractives (9.97% and 11.41%, respectively), which affect the efficiency of the bioconversion of polysaccharides to sugars.					
36771117	7	94	dep	technologies	1593:1604	arg1	reducing					1649:1656	reducing	1649:1656	reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials)	1649:1859	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	7	94	dep	technologies	1593:1604	arg1	obtaining					1607:1615	obtaining	1607:1615	obtaining value-added products	1607:1636	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
36771117	2	95	theme	chemical	295:302	arg1	composition					304:314	the chemical composition	291:314	the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2	291:583	The goal of the research work was to determine the relationship between the chemical composition of solid residues from biomass after acid pretreatment with H2SO4, alkaline pretreatment with NaOH, and a steam explosion pretreatment and the recovery of sugars and lignin after further enzymatic hydrolysis with the application of an industrial cellulase Cellic CTec2.					
36771117	7	96	theme	materials	1850:1858	arg1	advantage					1811:1819	advantage	1811:1819	advantage of these renewable, low-cost materials	1811:1858	The results pave the way for the efficient and perspective utilization of shells through the use of inexpensive, simple and affordable chemical technologies, obtaining value-added products, and thus, reducing the amount of environmental pollution (compared to the usual disposal practice of direct burning) and energy and material external dependency (by taking advantage of these renewable, low-cost materials).					
35469946	8	0	theme	full-thickness	1149:1162	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	0	1	with	composites	44:53	arg1	angiogenesis					94:105	angiogenesis	94:105	angiogenesis	94:105	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	0	1	with	composites	44:53	arg1	inhibition					82:91	promoted inflammation inhibition	60:91	promoted inflammation inhibition	60:91	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	0	1	with	composites	44:53	arg1	regeneration					125:136	hair follicle regeneration	111:136	hair follicle regeneration	111:136	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	1	2	theme	wound	261:265	arg1	healing					267:273	wound healing	261:273	wound healing	261:273	Soybean protein, as a safe and low-cost alternative to animal protein, attracts increasing attention in wound healing.					
35469946	5	3	theme	native	703:708	arg1	BC					710:711	native BC	703:711	native BC	703:711	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	8	4	theme	collagen	1020:1027	arg1	deposition					1029:1038	collagen deposition	1020:1038	collagen deposition	1020:1038	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	2	5	theme	protein	404:410	arg1	separation					382:391	separation	382:391	separation of soybean protein	382:410	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	2	6	with	beta-conglycinin	298:313	arg1	solubility					349:358	high solubility	344:358	high solubility	344:358	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	0	7	theme	follicle	116:123	arg1	regeneration					125:136	hair follicle regeneration	111:136	hair follicle regeneration	111:136	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	8	8	theme	enhanced	1041:1048	arg1	angiogenesis					1050:1061	enhanced angiogenesis	1041:1061	enhanced angiogenesis	1041:1061	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	6	9	theme	soybean	804:810	arg1	proteins					812:819	more soybean proteins	799:819	more soybean proteins	799:819	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	6	10	theme	Soybean	714:720	arg1	protein					722:728	Soybean protein	714:728	Soybean protein	714:728	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	0	11	theme	hair	111:114	arg1	regeneration					125:136	hair follicle regeneration	111:136	hair follicle regeneration	111:136	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	5	12	theme	BC/7S	662:666	arg1	hydrophilicity					644:657	hydrophilicity	644:657	hydrophilicity	644:657	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	5	12	theme	BC/7S	662:666	arg1	roughness					630:638	surface roughness	622:638	surface roughness	622:638	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	6	13	theme	more	799:802	arg1	proteins					812:819	more soybean proteins	799:819	more soybean proteins	799:819	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	9	14	theme	considerable	1346:1357	arg1	amount					1359:1364	the larger considerable amount	1335:1364	the larger considerable amount of soybean protein released by BC/11S	1335:1402	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	9	14	theme	considerable	1346:1357	arg1	protein					1377:1383	soybean protein	1369:1383	soybean protein	1369:1383	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	4	15	theme	isolates	584:591	arg1	self-assembly					551:563	the successful self-assembly	536:563	the successful self-assembly of soybean protein isolates on the nanofibers of BC	536:615	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	8	16	theme	rats	1179:1182	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	3	17	theme	cellulose	453:461	arg1	composites					468:477	modified bacterial cellulose (BC) composites	434:477	modified bacterial cellulose (BC) composites	434:477	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	2	18	theme	present	283:289	arg1	study					291:295	the present study	279:295	the present study	279:295	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	1	19	theme	safe	179:182	arg1	alternative					197:207	a safe and low-cost alternative	177:207	a safe and low-cost alternative to animal protein	177:225	Soybean protein, as a safe and low-cost alternative to animal protein, attracts increasing attention in wound healing.					
35469946	6	20	attach	released	748:755	arg1	BC/11S					772:777	BC/11S	772:777	BC/11S	772:777	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	6	20	attach	released	748:755	arg2	protein					722:728	Soybean protein	714:728	Soybean protein	714:728	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	6	20	attach	released	748:755	arg1	BC/7S					762:766	BC/7S	762:766	BC/7S	762:766	Soybean protein could be steadily released from BC/7S and BC/11S and BC/11S released more soybean proteins than BC/7S.					
35469946	4	21	theme	protein	576:582	arg1	isolates					584:591	soybean protein isolates	568:591	soybean protein isolates	568:591	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	7	22	theme	I	941:941	arg1	collagen					943:950	type I collagen	936:950	type I collagen expression	936:961	In vitro, BC/7S and BC/11S supported fibroblasts attachment and promoted fibroblasts proliferation and type I collagen expression.					
35469946	4	23	from	self-assembly	551:563	arg1	nanofibers					600:609	the nanofibers	596:609	the nanofibers of BC	596:615	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	0	24	theme	cellulose/soybean	10:26	arg1	protein					28:34	Bacterial cellulose/soybean protein	0:34	Bacterial cellulose/soybean protein	0:34	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	9	25	theme	collagen	1266:1273	arg1	depositions					1275:1285	more collagen depositions	1261:1285	more collagen depositions	1261:1285	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	5	26	theme	surface	622:628	arg1	roughness					630:638	surface roughness	622:638	surface roughness	622:638	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	7	27	theme	collagen	943:950	arg1	expression					952:961	type I collagen expression	936:961	type I collagen expression	936:961	In vitro, BC/7S and BC/11S supported fibroblasts attachment and promoted fibroblasts proliferation and type I collagen expression.					
35469946	1	28	theme	low-cost	188:195	arg1	alternative					197:207	a safe and low-cost alternative	177:207	a safe and low-cost alternative to animal protein	177:225	Soybean protein, as a safe and low-cost alternative to animal protein, attracts increasing attention in wound healing.					
35469946	0	29	theme	Bacterial	0:8	arg1	protein					28:34	Bacterial cellulose/soybean protein	0:34	Bacterial cellulose/soybean protein	0:34	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	4	30	theme	successful	540:549	arg1	self-assembly					551:563	the successful self-assembly	536:563	the successful self-assembly of soybean protein isolates on the nanofibers of BC	536:615	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	8	31	theme	hair	1067:1070	arg1	regeneration					1081:1092	hair follicle regeneration	1067:1092	hair follicle regeneration	1067:1092	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	8	32	from	formation	1119:1127	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	2	33	theme	high	344:347	arg1	solubility					349:358	high solubility	344:358	high solubility	344:358	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	7	34	theme	type	936:939	arg1	collagen					943:950	type I collagen	936:950	type I collagen expression	936:961	In vitro, BC/7S and BC/11S supported fibroblasts attachment and promoted fibroblasts proliferation and type I collagen expression.					
35469946	3	35	theme	bacterial	443:451	arg1	BC					464:465	BC	464:465	BC	464:465	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	3	35	theme	bacterial	443:451	arg1	cellulose					453:461	bacterial cellulose	443:461	modified bacterial cellulose (BC) composites	434:477	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	8	36	from	deposition	1029:1038	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	0	37	theme	wound	142:146	arg1	healing					148:154	wound healing	142:154	wound healing	142:154	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	2	38	with	glycinin	324:331	arg1	solubility					349:358	high solubility	344:358	high solubility	344:358	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	1	39	theme	animal	212:217	arg1	protein					219:225	animal protein	212:225	animal protein	212:225	Soybean protein, as a safe and low-cost alternative to animal protein, attracts increasing attention in wound healing.					
35469946	10	40	theme	wound	1479:1483	arg1	dressings					1485:1493	wound dressings	1479:1493	wound dressings	1479:1493	These results indicate that BC/7S and BC/11S are potential candidates for wound dressings.					
35469946	9	41	theme	faster	1231:1236	arg1	rate					1252:1255	a faster wound healing rate	1229:1255	a faster wound healing rate	1229:1255	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	2	42	theme	soybean	396:402	arg1	protein					404:410	soybean protein	396:410	soybean protein	396:410	In the present study, beta-conglycinin (7S) and glycinin (11S) with high solubility were obtained through separation of soybean protein.					
35469946	5	43	dep	roughness	630:638	arg1	The					618:620	The	618:620	The	618:620	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	9	44	theme	larger	1339:1344	arg1	amount					1359:1364	the larger considerable amount	1335:1364	the larger considerable amount of soybean protein released by BC/11S	1335:1402	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	9	44	theme	larger	1339:1344	arg1	protein					1377:1383	soybean protein	1369:1383	soybean protein	1369:1383	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	4	45	theme	soybean	568:574	arg1	isolates					584:591	soybean protein isolates	568:591	soybean protein isolates	568:591	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	8	46	from	inflammation	1133:1144	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	3	47	theme	modified	434:441	arg1	composites					468:477	modified bacterial cellulose (BC) composites	434:477	modified bacterial cellulose (BC) composites	434:477	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	0	48	theme	inflammation	69:80	arg1	inhibition					82:91	promoted inflammation inhibition	60:91	promoted inflammation inhibition	60:91	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	8	49	from	regeneration	1081:1092	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	8	50	theme	reduced	1106:1112	arg1	formation					1119:1127	reduced scar formation	1106:1127	reduced scar formation	1106:1127	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	9	51	theme	healing	1244:1250	arg1	rate					1252:1255	a faster wound healing rate	1229:1255	a faster wound healing rate	1229:1255	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	3	52	dep	7S	424:425	arg1	composites					468:477	modified bacterial cellulose (BC) composites	434:477	modified bacterial cellulose (BC) composites	434:477	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	0	53	theme	promoted	60:67	arg1	inhibition					82:91	promoted inflammation inhibition	60:91	promoted inflammation inhibition	60:91	Bacterial cellulose/soybean protein isolate composites with promoted inflammation inhibition, angiogenesis and hair follicle regeneration for wound healing.					
35469946	5	54	theme	BC/11S	672:677	arg1	hydrophilicity					644:657	hydrophilicity	644:657	hydrophilicity	644:657	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	5	54	theme	BC/11S	672:677	arg1	roughness					630:638	surface roughness	622:638	surface roughness	622:638	The surface roughness and hydrophilicity of BC/7S and BC/11S decreased compared with native BC.					
35469946	10	55	theme	potential	1454:1462	arg1	BC/7S					1433:1437	BC/7S	1433:1437	BC/7S	1433:1437	These results indicate that BC/7S and BC/11S are potential candidates for wound dressings.					
35469946	10	55	theme	potential	1454:1462	arg1	BC/11S					1443:1448	BC/11S	1443:1448	BC/11S	1443:1448	These results indicate that BC/7S and BC/11S are potential candidates for wound dressings.					
35469946	10	55	theme	potential	1454:1462	arg1	candidates					1464:1473	potential candidates	1454:1473	potential candidates for wound dressings	1454:1493	These results indicate that BC/7S and BC/11S are potential candidates for wound dressings.					
35469946	9	56	theme	wound	1238:1242	arg1	healing					1244:1250	wound healing	1238:1250	a faster wound healing rate	1229:1255	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	7	57	theme	fibroblasts	906:916	arg1	proliferation					918:930	fibroblasts proliferation	906:930	fibroblasts proliferation	906:930	In vitro, BC/7S and BC/11S supported fibroblasts attachment and promoted fibroblasts proliferation and type I collagen expression.					
35469946	8	58	from	angiogenesis	1050:1061	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	8	59	theme	wound	1002:1006	arg1	healing					1008:1014	wound healing	1002:1014	wound healing	1002:1014	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	9	60	theme	soybean	1369:1375	arg1	protein					1377:1383	soybean protein	1369:1383	soybean protein	1369:1383	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	8	61	theme	scar	1114:1117	arg1	formation					1119:1127	reduced scar formation	1106:1127	reduced scar formation	1106:1127	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	9	62	theme	more	1261:1264	arg1	depositions					1275:1285	more collagen depositions	1261:1285	more collagen depositions	1261:1285	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	1	63	theme	Soybean	157:163	arg1	protein					165:171	Soybean protein	157:171	Soybean protein	157:171	Soybean protein, as a safe and low-cost alternative to animal protein, attracts increasing attention in wound healing.					
35469946	9	64	theme	protein	1377:1383	arg1	amount					1359:1364	the larger considerable amount	1335:1364	the larger considerable amount of soybean protein released by BC/11S	1335:1402	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	9	64	theme	protein	1377:1383	arg1	protein					1377:1383	soybean protein	1369:1383	soybean protein	1369:1383	Moreover, wounds treated with BC/11S showed a faster wound healing rate and more collagen depositions than those of BC/7S, which may be attributed to the larger considerable amount of soybean protein released by BC/11S.					
35469946	8	65	from	healing	1008:1014	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	4	66	theme	BC	614:615	arg1	nanofibers					600:609	the nanofibers	596:609	the nanofibers of BC	596:615	Results confirmed the successful self-assembly of soybean protein isolates on the nanofibers of BC.					
35469946	8	67	theme	follicle	1072:1079	arg1	regeneration					1081:1092	hair follicle regeneration	1067:1092	hair follicle regeneration	1067:1092	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
35469946	3	68	theme	self-assembly	496:508	arg1	method					510:515	self-assembly method	496:515	self-assembly method	496:515	Afterward, 7S or 11S modified bacterial cellulose (BC) composites were produced by self-assembly method.					
35469946	7	69	theme	fibroblasts	870:880	arg1	attachment					882:891	fibroblasts attachment	870:891	fibroblasts attachment	870:891	In vitro, BC/7S and BC/11S supported fibroblasts attachment and promoted fibroblasts proliferation and type I collagen expression.					
35469946	8	70	theme	skin	1164:1167	arg1	wounds					1169:1174	full-thickness skin wounds	1149:1174	full-thickness skin wounds of rats	1149:1182	In vivo, BC/7S and BC/11S facilitated wound healing and collagen deposition, enhanced angiogenesis and hair follicle regeneration, as well as reduced scar formation and inflammation in full-thickness skin wounds of rats.					
36194832	0	0	theme	Oil-Water	98:106	arg1	Separation					108:117	Highly Efficient Oil-Water Separation	81:117	Highly Efficient Oil-Water Separation	81:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	1	1	contain	has	162:164	arg2	attention					182:190	kept continuous attention	166:190	kept continuous attention	166:190	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	1	1	contain	has	162:164	arg1	membrane					153:160	the high-anti-fouling membrane	131:160	Developing the high-anti-fouling membrane	120:160	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	8	2	theme	as-prepared	1382:1392	arg1	membranes					1394:1402	the as-prepared membranes	1378:1402	the as-prepared membranes into the harsh environments	1378:1430	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	6	3	theme	adhesion	1065:1072	arg1	behaviors					1074:1082	ultralow crude oil adhesion behaviors	1046:1082	ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar))	1046:1196	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	0	4	theme	Efficient	88:96	arg1	Separation					108:117	Highly Efficient Oil-Water Separation	81:117	Highly Efficient Oil-Water Separation	81:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	5	5	dep	6160	908:911	arg1	to					905:906	to	905:906	to	905:906	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	1	6	theme	oil/water	195:203	arg1	treatment					214:222	oil/water emulsion treatment	195:222	oil/water emulsion treatment	195:222	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	8	7	theme	oil	1547:1549	arg1	rejection					1551:1559	oil rejection	1547:1559	oil rejection	1547:1559	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	6	8	theme	oil	1061:1063	arg1	behaviors					1074:1082	ultralow crude oil adhesion behaviors	1046:1082	ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar))	1046:1196	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	7	9	theme	electrostatic	1212:1224	arg1	interaction					1226:1236	electrostatic interaction	1212:1236	electrostatic interaction	1212:1236	Furthermore, electrostatic interaction and physical enwinding-wrapping between CMC and UiO-66-NH2 also endowed the composite membranes with outstanding stability.					
36194832	6	10	dep	±	1166:1166	arg1	L/					1184:1185	± 87 L/	1179:1185	746 ± 60 to 5224 ± 87 L/(m2·h·bar)	1162:1195	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	6	10	dep	±	1166:1166	arg1	m2·h·bar					1187:1194	m2·h·bar	1187:1194	m2·h·bar	1187:1194	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	5	11	dep	±	900:900	arg1	L/					918:919	62 to 6160 ± 81 L/	902:919	62 to 6160 ± 81 L/(m2·h·bar)	902:929	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	5	11	dep	±	900:900	arg1	%					946:946	above 99.08%	935:946	above 99.08% toward the different light oil emulsions	935:987	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	5	11	dep	±	900:900	arg1	m2·h·bar					921:928	m2·h·bar	921:928	m2·h·bar	921:928	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	8	12	theme	separation	1527:1536	arg1	ability					1538:1544	separation ability	1527:1544	separation ability (oil rejection was above 99.0%)	1527:1576	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	2	13	dep	face	391:394	arg1	wastewater					415:424	the real crude oil wastewater	396:424	face the real crude oil wastewater	391:424	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	4	14	theme	layer	724:728	arg1	micro-nanostructure					682:700	micro-nanostructure	682:700	micro-nanostructure	682:700	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	4	14	theme	layer	724:728	arg1	hydrophilicity					663:676	hydrophilicity	663:676	hydrophilicity	663:676	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	6	15	theme	crude	1055:1059	arg1	behaviors					1074:1082	ultralow crude oil adhesion behaviors	1046:1082	ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar))	1046:1196	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	4	16	theme	CMC/UiO-66-NH2	744:757	arg1	membranes					759:767	the obtained CMC/UiO-66-NH2 membranes	731:767	the obtained CMC/UiO-66-NH2 membranes	731:767	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	3	17	theme	composite	582:590	arg1	membrane					592:599	an anti-oil-fouling CMC/UiO-66-NH2 composite membrane	547:599	an anti-oil-fouling CMC/UiO-66-NH2 composite membrane	547:599	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	1	18	theme	kept	166:169	arg1	attention					182:190	kept continuous attention	166:190	kept continuous attention	166:190	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	2	19	theme	membrane	379:386	arg1	application					362:372	application	362:372	application	362:372	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	2	19	theme	membrane	379:386	arg1	development					346:356	development	346:356	development	346:356	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	7	20	with	endowed	1302:1308	arg1	stability					1351:1359	outstanding stability	1339:1359	outstanding stability	1339:1359	Furthermore, electrostatic interaction and physical enwinding-wrapping between CMC and UiO-66-NH2 also endowed the composite membranes with outstanding stability.					
36194832	8	21	theme	harsh	1413:1417	arg1	environments					1419:1430	the harsh environments	1409:1430	the harsh environments	1409:1430	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	5	22	theme	oil	975:977	arg1	emulsions					979:987	the different light oil emulsions	955:987	the different light oil emulsions	955:987	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	1	23	theme	emulsion	205:212	arg1	treatment					214:222	oil/water emulsion treatment	195:222	oil/water emulsion treatment	195:222	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	6	24	theme	ultralow	1046:1053	arg1	behaviors					1074:1082	ultralow crude oil adhesion behaviors	1046:1082	ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar))	1046:1196	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	5	25	theme	separation	868:877	arg1	capability					879:888	the effective separation capability	854:888	the effective separation capability	854:888	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	3	26	theme	anti-oil-fouling	550:565	arg1	CMC/UiO-66-NH2					567:580	an anti-oil-fouling CMC/UiO-66-NH2	547:580	an anti-oil-fouling CMC/UiO-66-NH2 composite membrane	547:599	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	27	theme	metal-organic	517:529	arg1	Zr-MOF					538:543	Zr-MOF	538:543	Zr-MOF	538:543	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	27	theme	metal-organic	517:529	arg1	frame					531:535	zirconium base metal-organic frame	502:535	zirconium base metal-organic frame (Zr-MOF)	502:544	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	28	theme	cellulose	482:490	arg1	hydrophilicity					443:456	the hydrophilicity	439:456	the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF)	439:544	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	0	29	theme	CMC/UiO-66-NH2	15:28	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	5	30	theme	effective	858:866	arg1	capability					879:888	the effective separation capability	854:888	the effective separation capability	854:888	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	7	31	theme	physical	1242:1249	arg1	enwinding-wrapping					1251:1268	physical enwinding-wrapping	1242:1268	physical enwinding-wrapping	1242:1268	Furthermore, electrostatic interaction and physical enwinding-wrapping between CMC and UiO-66-NH2 also endowed the composite membranes with outstanding stability.					
36194832	4	32	theme	CMC/UiO-66-NH2	709:722	arg1	layer					724:728	the CMC/UiO-66-NH2 layer	705:728	the CMC/UiO-66-NH2 layer	705:728	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	9	33	theme	CMC/UiO-66-NH2	1590:1603	arg1	membranes					1615:1623	CMC/UiO-66-NH2 composite membranes	1590:1623	CMC/UiO-66-NH2 composite membranes	1590:1623	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	6	34	theme	high	1151:1154	arg1	flux					1156:1159	a considerably high flux	1136:1159	a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar))	1136:1196	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	6	34	theme	high	1151:1154	arg1	±					1166:1166	746 ± 60 to 5224 ± 87 L/(m2·h·bar)	1162:1195	746 ± 60 to 5224 ± 87 L/(m2·h·bar)	1162:1195	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	2	35	theme	oil	411:413	arg1	wastewater					415:424	the real crude oil wastewater	396:424	face the real crude oil wastewater	391:424	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	9	36	theme	oily	1671:1674	arg1	treatment					1685:1693	real oily emulsion treatment	1666:1693	real oily emulsion treatment	1666:1693	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	4	37	theme	oil	821:823	arg1	resistance					825:834	desired oil resistance	813:834	desired oil resistance	813:834	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	9	38	theme	composite	1605:1613	arg1	membranes					1615:1623	CMC/UiO-66-NH2 composite membranes	1590:1623	CMC/UiO-66-NH2 composite membranes	1590:1623	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	2	39	theme	crude	405:409	arg1	wastewater					415:424	the real crude oil wastewater	396:424	face the real crude oil wastewater	391:424	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	0	40	theme	with	39:42	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	8	41	theme	contact	1493:1499	arg1	angles					1501:1506	high underwater-oil contact angles	1473:1506	high underwater-oil contact angles (UWOCA > 155°)	1473:1521	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	8	41	theme	contact	1493:1499	arg1	>					1515:1515	UWOCA > 155°	1509:1520	UWOCA > 155°	1509:1520	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	8	42	theme	UWOCA	1509:1513	arg1	angles					1501:1506	high underwater-oil contact angles	1473:1506	high underwater-oil contact angles (UWOCA > 155°)	1473:1521	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	8	42	theme	UWOCA	1509:1513	arg1	>					1515:1515	UWOCA > 155°	1509:1520	UWOCA > 155°	1509:1520	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	1	43	theme	Developing	120:129	arg1	membrane					153:160	the high-anti-fouling membrane	131:160	Developing the high-anti-fouling membrane	120:160	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	5	44	theme	±	913:913	arg1	L/					918:919	62 to 6160 ± 81 L/	902:919	62 to 6160 ± 81 L/(m2·h·bar)	902:929	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	5	44	theme	±	913:913	arg1	m2·h·bar					921:928	m2·h·bar	921:928	m2·h·bar	921:928	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	0	45	theme	Membrane	30:37	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	6	46	theme	CMC/UiO-66-NH2	1012:1025	arg1	membrane					1027:1034	the CMC/UiO-66-NH2 membrane	1008:1034	the CMC/UiO-66-NH2 membrane	1008:1034	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	6	47	theme	±	1179:1179	arg1	L/					1184:1185	± 87 L/	1179:1185	746 ± 60 to 5224 ± 87 L/(m2·h·bar)	1162:1195	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	6	47	theme	±	1179:1179	arg1	m2·h·bar					1187:1194	m2·h·bar	1187:1194	m2·h·bar	1187:1194	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	1	48	theme	continuous	171:180	arg1	attention					182:190	kept continuous attention	166:190	kept continuous attention	166:190	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	0	49	theme	Oil	55:57	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	4	50	theme	underwater	779:788	arg1	superoleophobicity					790:807	underwater superoleophobicity	779:807	underwater superoleophobicity	779:807	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	3	51	theme	sodium	461:466	arg1	CMC					493:495	CMC	493:495	CMC	493:495	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	51	theme	sodium	461:466	arg1	cellulose					482:490	sodium carboxymethyl cellulose	461:490	sodium carboxymethyl cellulose (CMC)	461:496	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	0	52	theme	Anti-Crude	44:53	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	2	53	theme	anti-fouling	259:270	arg1	membranes					272:280	anti-fouling membranes	259:280	anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater	259:424	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	9	54	theme	emulsion	1676:1683	arg1	treatment					1685:1693	real oily emulsion treatment	1666:1693	real oily emulsion treatment	1666:1693	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	6	55	theme	oil	1101:1103	arg1	emulsions					1105:1113	the crude oil emulsions	1091:1113	the crude oil emulsions	1091:1113	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	3	56	theme	carboxymethyl	468:480	arg1	CMC					493:495	CMC	493:495	CMC	493:495	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	56	theme	carboxymethyl	468:480	arg1	cellulose					482:490	sodium carboxymethyl cellulose	461:490	sodium carboxymethyl cellulose (CMC)	461:496	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	1	57	theme	high-anti-fouling	135:151	arg1	membrane					153:160	the high-anti-fouling membrane	131:160	Developing the high-anti-fouling membrane	120:160	Developing the high-anti-fouling membrane has kept continuous attention in oil/water emulsion treatment.					
36194832	0	58	theme	Adhesion	59:66	arg1	Property					68:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property	15:75	CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation	15:117	Self-Assembled CMC/UiO-66-NH2 Membrane with Anti-Crude Oil Adhesion Property for Highly Efficient Oil-Water Separation.					
36194832	4	59	dep	hydrophilicity	663:676	arg1	the					659:661	the	659:661	the	659:661	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	3	60	theme	self-assembly	622:634	arg1	method					636:641	a self-assembly method	620:641	a self-assembly method	620:641	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	7	61	theme	composite	1314:1322	arg1	membranes					1324:1332	the composite membranes	1310:1332	the composite membranes	1310:1332	Furthermore, electrostatic interaction and physical enwinding-wrapping between CMC and UiO-66-NH2 also endowed the composite membranes with outstanding stability.					
36194832	3	62	theme	frame	531:535	arg1	hydrophilicity					443:456	the hydrophilicity	439:456	the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF)	439:544	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	8	63	theme	high	1473:1476	arg1	angles					1501:1506	high underwater-oil contact angles	1473:1506	high underwater-oil contact angles (UWOCA > 155°)	1473:1521	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	8	63	theme	high	1473:1476	arg1	>					1515:1515	UWOCA > 155°	1509:1520	UWOCA > 155°	1509:1520	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	5	64	theme	light	969:973	arg1	emulsions					979:987	the different light oil emulsions	955:987	the different light oil emulsions	955:987	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	2	65	theme	low-viscosity	300:312	arg1	oils					314:317	low-viscosity oils	300:317	low-viscosity oils	300:317	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	9	66	theme	promising	1643:1651	arg1	prospects					1653:1661	promising prospects	1643:1661	promising prospects	1643:1661	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	3	67	theme	zirconium	502:510	arg1	Zr-MOF					538:543	Zr-MOF	538:543	Zr-MOF	538:543	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	67	theme	zirconium	502:510	arg1	frame					531:535	zirconium base metal-organic frame	502:535	zirconium base metal-organic frame (Zr-MOF)	502:544	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	6	68	theme	crude	1095:1099	arg1	emulsions					1105:1113	the crude oil emulsions	1091:1113	the crude oil emulsions	1091:1113	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	5	69	theme	different	959:967	arg1	emulsions					979:987	the different light oil emulsions	955:987	the different light oil emulsions	955:987	It could display the effective separation capability with 1282 ± 62 to 6160 ± 81 L/(m2·h·bar) and above 99.08% toward the different light oil emulsions.					
36194832	3	70	theme	CMC/UiO-66-NH2	567:580	arg1	membrane					592:599	an anti-oil-fouling CMC/UiO-66-NH2 composite membrane	547:599	an anti-oil-fouling CMC/UiO-66-NH2 composite membrane	547:599	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	2	71	dep	development	346:356	arg1	the					342:344	the	342:344	the	342:344	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	4	72	theme	desired	813:819	arg1	resistance					825:834	desired oil resistance	813:834	desired oil resistance	813:834	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	7	73	theme	outstanding	1339:1349	arg1	stability					1351:1359	outstanding stability	1339:1359	outstanding stability	1339:1359	Furthermore, electrostatic interaction and physical enwinding-wrapping between CMC and UiO-66-NH2 also endowed the composite membranes with outstanding stability.					
36194832	6	74	dep	5224	1174:1177	arg1	to					1171:1172	to	1171:1172	to	1171:1172	More importantly, the CMC/UiO-66-NH2 membrane displayed ultralow crude oil adhesion behaviors toward the crude oil emulsions, which could achieve a considerably high flux (746 ± 60 to 5224 ± 87 L/(m2·h·bar)).					
36194832	9	75	theme	real	1666:1669	arg1	treatment					1685:1693	real oily emulsion treatment	1666:1693	real oily emulsion treatment	1666:1693	Therefore, CMC/UiO-66-NH2 composite membranes could demonstrate promising prospects in real oily emulsion treatment.					
36194832	2	76	theme	real	400:403	arg1	wastewater					415:424	the real crude oil wastewater	396:424	face the real crude oil wastewater	391:424	However, the majority of works on anti-fouling membranes mainly focused on low-viscosity oils, which greatly limited the development and application of a membrane to face the real crude oil wastewater.					
36194832	3	77	theme	base	512:515	arg1	Zr-MOF					538:543	Zr-MOF	538:543	Zr-MOF	538:543	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	3	77	theme	base	512:515	arg1	frame					531:535	zirconium base metal-organic frame	502:535	zirconium base metal-organic frame (Zr-MOF)	502:544	Inspired by the hydrophilicity of sodium carboxymethyl cellulose (CMC) and zirconium base metal-organic frame (Zr-MOF), an anti-oil-fouling CMC/UiO-66-NH2 composite membrane was constructed by a self-assembly method.					
36194832	8	78	theme	underwater-oil	1478:1491	arg1	angles					1501:1506	high underwater-oil contact angles	1473:1506	high underwater-oil contact angles (UWOCA > 155°)	1473:1521	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	8	78	theme	underwater-oil	1478:1491	arg1	>					1515:1515	UWOCA > 155°	1509:1520	UWOCA > 155°	1509:1520	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36194832	4	79	theme	obtained	735:742	arg1	membranes					759:767	the obtained CMC/UiO-66-NH2 membranes	731:767	the obtained CMC/UiO-66-NH2 membranes	731:767	Profiting from the hydrophilicity and micro-nanostructure of the CMC/UiO-66-NH2 layer, the obtained CMC/UiO-66-NH2 membranes displayed underwater superoleophobicity and desired oil resistance.					
36194832	8	80	dep	ability	1538:1544	arg1	%					1575:1575	99.0%	1571:1575	99.0%	1571:1575	After immersing the as-prepared membranes into the harsh environments for 24 h, the membranes still maintained high underwater-oil contact angles (UWOCA > 155°) and separation ability (oil rejection was above 99.0%).					
36773881	0	0	theme	Suzuki	69:74	arg1	reactions					91:99	Suzuki cross-coupling reactions	69:99	Suzuki cross-coupling reactions	69:99	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	7	1	theme	appealing	1258:1266	arg1	pathway					1283:1289	an appealing and intriguing pathway	1255:1289	an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations	1255:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	4	2	theme	lower	794:798	arg1	temperature					809:819	lower reaction temperature	794:819	lower reaction temperature	794:819	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	6	3	theme	complex	1217:1223	arg1	structure					1225:1233	a possibly multifunctional complex structure	1190:1233	a possibly multifunctional complex structure	1190:1233	Moreover, we proposed a possibly multifunctional complex structure.					
36773881	4	4	theme	catalytic	626:634	arg1	studies					636:642	The catalytic studies	622:642	The catalytic studies	622:642	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	6	5	theme	multifunctional	1201:1215	arg1	structure					1225:1233	a possibly multifunctional complex structure	1190:1233	a possibly multifunctional complex structure	1190:1233	Moreover, we proposed a possibly multifunctional complex structure.					
36773881	4	6	theme	catalytic	754:762	arg1	system					764:769	catalytic system	754:769	catalytic system	754:769	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	7	theme	FT-IR	535:539	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	5	8	theme	several	1129:1135	arg1	cycles					1137:1142	several cycles	1129:1142	several cycles	1129:1142	The experiments on reusability demonstrate that Starch-SB-Pd(II), which was prepared from functionalized starch, could be readily recycled several cycles through centrifugation.					
36773881	0	9	theme	cross-coupling	76:89	arg1	reactions					91:99	Suzuki cross-coupling reactions	69:99	Suzuki cross-coupling reactions	69:99	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	0	10	from	biosupport	41:50	arg1	reactions					91:99	Suzuki cross-coupling reactions	69:99	Suzuki cross-coupling reactions	69:99	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	4	11	theme	reaction	800:807	arg1	temperature					809:819	lower reaction temperature	794:819	lower reaction temperature	794:819	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	12	from	interactions	868:879	arg1	starch					919:924	starch	919:924	starch (Schiff base, hydroxy and amine groups) with palladium species	919:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	13	theme	capturing	900:908	arg1	sites					910:914	multifunctional capturing sites	884:914	multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	884:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	14	theme	high	652:655	arg1	%					676:676	up to 99 %	667:676	up to 99 %	667:676	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	14	theme	high	652:655	arg1	activity					657:664	high activity	652:664	high activity (up to 99 %)	652:677	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	15	theme	multifunctional	884:898	arg1	sites					910:914	multifunctional capturing sites	884:914	multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	884:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	16	theme	new	440:442	arg1	air					444:446	This new air	435:446	This new air	435:446	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	2	17	theme	aforementioned	276:289	arg1	characteristics					291:305	the aforementioned characteristics	272:305	the aforementioned characteristics	272:305	In this study, taking the aforementioned characteristics into consideration, we designed a modified starch (Starch-SB), which serves as supporting material for palladium stabilization.					
36773881	3	18	theme	TGA	547:549	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	0	19	theme	Schiff	0:5	arg1	base					7:10	Schiff base	0:10	Schiff base	0:10	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	4	20	theme	mild	777:780	arg1	conditions					782:791	mild conditions	777:791	mild conditions (lower reaction temperature and green solvents)	777:839	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	1	21	used	used	116:119	arg2	Starch					102:107	Starch	102:107	Starch	102:107	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	1	22	theme	available	163:171	arg1	polysaccharide					184:197	a readily available, non-toxic polysaccharide	153:197	a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability	153:247	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	1	22	theme	available	163:171	arg1	it					147:148	it	147:148	it	147:148	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	1	23	with	polysaccharide	184:197	arg1	biodegradability					232:247	biodegradability	232:247	biodegradability	232:247	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	1	23	with	polysaccharide	184:197	arg1	functionality					214:226	adaptable functionality	204:226	adaptable functionality	204:226	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	7	24	theme	polysaccharide	1314:1327	arg1	utilization					1299:1309	the utilization	1295:1309	the utilization of polysaccharide as crucial support in green chemical transformations	1295:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	3	25	theme	XRD	542:544	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	2	26	theme	palladium	410:418	arg1	stabilization					420:432	palladium stabilization	410:432	palladium stabilization	410:432	In this study, taking the aforementioned characteristics into consideration, we designed a modified starch (Starch-SB), which serves as supporting material for palladium stabilization.					
36773881	7	27	theme	chemical	1357:1364	arg1	transformations					1366:1380	green chemical transformations	1351:1380	green chemical transformations	1351:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	3	28	theme	NMR	583:585	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	7	29	theme	green	1351:1355	arg1	transformations					1366:1380	green chemical transformations	1351:1380	green chemical transformations	1351:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	3	30	theme	robust	468:473	arg1	[Starch-SB-Pd					495:507	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	4	31	theme	cooperative	856:866	arg1	interactions					868:879	the cooperative interactions	852:879	the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	852:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	32	theme	SEM	557:559	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	4	33	dep	Suzuki	696:701	arg1	supported					744:752	supported	744:752	supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	744:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	34	theme	Schiff	927:932	arg1	base					934:937	Schiff base	927:937	Schiff base	927:937	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	35	theme	CP/MAS	572:577	arg1	NMR					583:585	CP/MAS 13C NMR	572:585	CP/MAS 13C NMR	572:585	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	1	36	dep	available	163:171	arg1	non-toxic					174:182	non-toxic	174:182	non-toxic	174:182	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	5	37	from	experiments	994:1004	arg1	reusability					1009:1019	reusability	1009:1019	reusability	1009:1019	The experiments on reusability demonstrate that Starch-SB-Pd(II), which was prepared from functionalized starch, could be readily recycled several cycles through centrifugation.					
36773881	4	38	theme	green	825:829	arg1	solvents					831:838	green solvents	825:838	green solvents	825:838	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	39	theme	13C	579:581	arg1	NMR					583:585	CP/MAS 13C NMR	572:585	CP/MAS 13C NMR	572:585	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	3	40	theme	XPS	552:554	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	4	41	with	starch	919:924	arg1	species					981:987	palladium species	971:987	palladium species	971:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	2	42	theme	modified	341:348	arg1	Starch-SB					358:366	Starch-SB	358:366	Starch-SB	358:366	In this study, taking the aforementioned characteristics into consideration, we designed a modified starch (Starch-SB), which serves as supporting material for palladium stabilization.					
36773881	2	42	theme	modified	341:348	arg1	starch					350:355	a modified starch	339:355	a modified starch (Starch-SB)	339:367	In this study, taking the aforementioned characteristics into consideration, we designed a modified starch (Starch-SB), which serves as supporting material for palladium stabilization.					
36773881	0	43	theme	promising	31:39	arg1	biosupport					41:50	A promising biosupport	29:50	A promising biosupport for palladium in Suzuki cross-coupling reactions	29:99	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	4	44	dep	starch	919:924	arg1	hydroxy					940:946	hydroxy	940:946	hydroxy	940:946	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	44	dep	starch	919:924	arg1	groups					958:963	amine groups	952:963	amine groups	952:963	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	44	dep	starch	919:924	arg1	base					934:937	Schiff base	927:937	Schiff base	927:937	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	45	theme	analytical	599:608	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	4	46	dep	conditions	782:791	arg1	solvents					831:838	green solvents	825:838	green solvents	825:838	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	46	dep	conditions	782:791	arg1	temperature					809:819	lower reaction temperature	794:819	lower reaction temperature	794:819	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	47	dep	99 	673:675	arg1	to					670:671	to	670:671	to	670:671	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	7	48	from	support	1340:1346	arg1	transformations					1366:1380	green chemical transformations	1351:1380	green chemical transformations	1351:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	5	49	theme	functionalized	1080:1093	arg1	starch					1095:1100	functionalized starch	1080:1100	functionalized starch	1080:1100	The experiments on reusability demonstrate that Starch-SB-Pd(II), which was prepared from functionalized starch, could be readily recycled several cycles through centrifugation.					
36773881	4	50	theme	cross-coupling	703:716	arg1	reactions					718:726	cross-coupling reactions	703:726	cross-coupling reactions for this starch	703:742	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	51	theme	TEM	567:569	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	7	52	theme	crucial	1332:1338	arg1	support					1340:1346	crucial support	1332:1346	crucial support in green chemical transformations	1332:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	3	53	theme	palladium	475:483	arg1	[Starch-SB-Pd					495:507	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	1	54	theme	adaptable	204:212	arg1	functionality					214:226	adaptable functionality	204:226	adaptable functionality	204:226	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	0	55	dep	modified	12:19	arg1	biosupport					41:50	A promising biosupport	29:50	A promising biosupport for palladium in Suzuki cross-coupling reactions	29:99	Schiff base modified starch: A promising biosupport for palladium in Suzuki cross-coupling reactions.					
36773881	3	56	theme	composite	485:493	arg1	[Starch-SB-Pd					495:507	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	4	57	from	starch	919:924	arg1	interactions					868:879	the cooperative interactions	852:879	the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	852:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	3	58	theme	ICP-MS	592:597	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	3	59	theme	EDX	562:564	arg1	techniques					610:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques	535:619	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	3	60	theme	moisture-stable	452:466	arg1	[Starch-SB-Pd					495:507	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	moisture-stable robust palladium composite [Starch-SB-Pd(II)	452:511	This new air and moisture-stable robust palladium composite [Starch-SB-Pd(II)] was characterized by FT-IR, XRD, TGA, XPS, SEM, EDX, TEM, CP/MAS 13C NMR, and ICP-MS analytical techniques.					
36773881	1	61	theme	diverse	124:130	arg1	fields					132:137	diverse fields	124:137	diverse fields	124:137	Starch can be used in diverse fields because it is a readily available, non-toxic polysaccharide with adaptable functionality and biodegradability.					
36773881	7	62	theme	intriguing	1272:1281	arg1	pathway					1283:1289	an appealing and intriguing pathway	1255:1289	an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations	1255:1380	This work presents an appealing and intriguing pathway for the utilization of polysaccharide as crucial support in green chemical transformations.					
36773881	4	63	theme	sites	910:914	arg1	interactions					868:879	the cooperative interactions	852:879	the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species	852:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	64	theme	amine	952:956	arg1	groups					958:963	amine groups	952:963	amine groups	952:963	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	65	theme	palladium	971:979	arg1	species					981:987	palladium species	971:987	palladium species	971:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36773881	4	66	from	sites	910:914	arg1	starch					919:924	starch	919:924	starch (Schiff base, hydroxy and amine groups) with palladium species	919:987	The catalytic studies exhibit high activity (up to 99 %) and stability in Suzuki cross-coupling reactions for this starch supported catalytic system under mild conditions (lower reaction temperature and green solvents) because of the cooperative interactions of multifunctional capturing sites on starch (Schiff base, hydroxy and amine groups) with palladium species.					
36746587	4	0	contain	had	677:679	arg1	beers					671:675	Pilsner beers	663:675	Pilsner beers	663:675	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	4	0	contain	had	677:679	arg2	content					690:696	a higher content	681:696	a higher content of high-molecular-weight AX	681:724	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	6	1	theme	beers	884:888	arg1	composition					865:875	the chemical composition	852:875	the chemical composition of the beers	852:888	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	6	2	dep	production	911:920	arg1	methods					922:928	methods	922:928	methods	922:928	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	0	3	from	occurrence	4:13	arg1	beers					82:86	commercial pilsner beers	63:86	commercial pilsner beers	63:86	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	3	from	occurrence	4:13	arg1	counterparts					112:123	their non-alcoholic counterparts	92:123	their non-alcoholic counterparts	92:123	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	4	theme	structural	334:343	arg1	heterogeneity					345:357	structural heterogeneity	334:357	structural heterogeneity	334:357	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	5	theme	non-alcoholic	98:110	arg1	counterparts					112:123	their non-alcoholic counterparts	92:123	their non-alcoholic counterparts	92:123	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	6	6	theme	beer	906:909	arg1	production					911:920	beer production methods and ingredient selection	906:953	production	911:920	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	4	7	theme	AX	723:724	arg1	content					690:696	a higher content	681:696	a higher content of high-molecular-weight AX	681:724	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	3	8	theme	number-average	543:556	arg1	degree					558:563	a number-average degree	541:563	a number-average degree of polymerisation of 4 to 308	541:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	1	9	dep	arabinoxylan	140:151	arg1	AX					154:155	AX	154:155	AX	154:155	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	3	10	dep	0.88	657:660	arg1	to					654:655	to	654:655	to	654:655	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	11	theme	ethanol	464:470	arg1	precipitation					472:484	graded ethanol precipitation	457:484	graded ethanol precipitation	457:484	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	12	from	range	640:644	arg1	degree					610:615	an average degree	599:615	an average degree of substitution in the range of 0.43 to 0.88	599:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	12	from	range	640:644	arg1	degree					558:563	a number-average degree	541:563	a number-average degree of polymerisation of 4 to 308	541:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	5	13	theme	structural	769:778	arg1	heterogeneity					780:792	The structural heterogeneity	765:792	The structural heterogeneity among the various commercial beers	765:827	The structural heterogeneity among the various commercial beers differed.					
36746587	6	14	theme	chemical	856:863	arg1	composition					865:875	the chemical composition	852:875	the chemical composition of the beers	852:888	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	5	15	theme	commercial	812:821	arg1	beers					823:827	the various commercial beers	800:827	the various commercial beers	800:827	The structural heterogeneity among the various commercial beers differed.					
36746587	3	16	from	degree	610:615	arg1	range					640:644	the range	636:644	the range of 0.43 to 0.88	636:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	1	17	theme	brewing	165:171	arg1	process					173:179	the brewing process	161:179	the brewing process	161:179	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	5	18	theme	various	804:810	arg1	beers					823:827	the various commercial beers	800:827	the various commercial beers	800:827	The structural heterogeneity among the various commercial beers differed.					
36746587	0	19	from	heterogeneity	30:42	arg1	beers					82:86	commercial pilsner beers	63:86	commercial pilsner beers	63:86	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	19	from	heterogeneity	30:42	arg1	counterparts					112:123	their non-alcoholic counterparts	92:123	their non-alcoholic counterparts	92:123	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	3	20	theme	polymerisation	568:581	arg1	degree					610:615	an average degree	599:615	an average degree of substitution in the range of 0.43 to 0.88	599:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	20	theme	polymerisation	568:581	arg1	degree					558:563	a number-average degree	541:563	a number-average degree of polymerisation of 4 to 308	541:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	21	dep	308	591:593	arg1	to					588:589	to	588:589	to	588:589	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	2	22	theme	counterparts	426:437	arg1	occurrence					319:328	occurrence	319:328	occurrence	319:328	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	22	theme	counterparts	426:437	arg1	heterogeneity					345:357	structural heterogeneity	334:357	structural heterogeneity	334:357	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	6	23	from	differences	1004:1014	arg1	content					1022:1028	AX content	1019:1028	AX content	1019:1028	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	6	23	from	differences	1004:1014	arg1	heterogeneity					1045:1057	structural heterogeneity	1034:1057	structural heterogeneity	1034:1057	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	2	24	from	AX	362:363	arg1	set					370:372	a set	368:372	a set of commercial pilsner	368:394	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	24	from	AX	362:363	arg1	pilsner					388:394	commercial pilsner	377:394	commercial pilsner	377:394	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	6	25	from	differences	891:901	arg1	production					911:920	beer production methods and ingredient selection	906:953	production	911:920	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	6	25	from	differences	891:901	arg1	selection					945:953	ingredient selection	934:953	ingredient selection	934:953	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	0	26	theme	structural	19:28	arg1	heterogeneity					30:42	structural heterogeneity	19:42	structural heterogeneity	19:42	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	1	27	from	impact	130:135	arg1	process					173:179	the brewing process	161:179	the brewing process	161:179	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	1	27	from	impact	130:135	arg1	beer					185:188	beer	185:188	beer	185:188	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	3	28	theme	308	591:593	arg1	polymerisation					568:581	polymerisation	568:581	polymerisation of 4 to 308	568:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	29	theme	graded	457:462	arg1	precipitation					472:484	graded ethanol precipitation	457:484	graded ethanol precipitation	457:484	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	2	30	dep	occurrence	319:328	arg1	the					315:317	the	315:317	the	315:317	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	31	theme	beers	396:400	arg1	occurrence					319:328	occurrence	319:328	occurrence	319:328	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	31	theme	beers	396:400	arg1	heterogeneity					345:357	structural heterogeneity	334:357	structural heterogeneity	334:357	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	3	32	with	beer	531:534	arg1	degree					610:615	an average degree	599:615	an average degree of substitution in the range of 0.43 to 0.88	599:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	32	with	beer	531:534	arg1	degree					558:563	a number-average degree	541:563	a number-average degree of polymerisation of 4 to 308	541:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	1	33	dep	process	173:179	arg1	characteristics					190:204	characteristics	190:204	characteristics	190:204	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	2	34	theme	pilsner	388:394	arg1	set					370:372	a set	368:372	a set of commercial pilsner	368:394	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	34	theme	pilsner	388:394	arg1	pilsner					388:394	commercial pilsner	377:394	commercial pilsner	377:394	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	4	35	theme	Pilsner	663:669	arg1	beers					671:675	Pilsner beers	663:675	Pilsner beers	663:675	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	2	36	gly	heterogeneity	345:357	arg1	counterparts					426:437	their non-alcoholic counterparts	406:437	their non-alcoholic counterparts	406:437	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	36	gly	heterogeneity	345:357	arg1	beers					396:400	AX in a set of commercial pilsner beers	362:400	AX in a set of commercial pilsner beers	362:400	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	3	37	theme	substitution	620:631	arg1	degree					610:615	an average degree	599:615	an average degree of substitution in the range of 0.43 to 0.88	599:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	37	theme	substitution	620:631	arg1	degree					558:563	a number-average degree	541:563	a number-average degree of polymerisation of 4 to 308	541:593	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	2	38	theme	non-alcoholic	412:424	arg1	counterparts					426:437	their non-alcoholic counterparts	406:437	their non-alcoholic counterparts	406:437	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	39	theme	commercial	377:386	arg1	pilsner					388:394	commercial pilsner	377:394	commercial pilsner	377:394	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	3	40	from	substitution	620:631	arg1	range					640:644	the range	636:644	the range of 0.43 to 0.88	636:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	4	41	theme	non-alcoholic	737:749	arg1	counterparts					751:762	their non-alcoholic counterparts	731:762	their non-alcoholic counterparts	731:762	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	4	42	theme	higher	683:688	arg1	content					690:696	a higher content	681:696	a higher content of high-molecular-weight AX	681:724	Pilsner beers had a higher content of high-molecular-weight AX than their non-alcoholic counterparts.					
36746587	0	43	theme	arabinoxylan	47:58	arg1	occurrence					4:13	occurrence	4:13	occurrence	4:13	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	43	theme	arabinoxylan	47:58	arg1	heterogeneity					30:42	structural heterogeneity	19:42	structural heterogeneity	19:42	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	6	44	used	used	972:975	arg2	differences					891:901	differences	891:901	differences in beer production methods and ingredient selection	891:953	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	3	45	theme	AX-rich	508:514	arg1	fractions					516:524	AX-rich fractions	508:524	AX-rich fractions	508:524	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	3	46	from	degree	558:563	arg1	range					640:644	the range	636:644	the range of 0.43 to 0.88	636:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	6	47	theme	ingredient	934:943	arg1	selection					945:953	ingredient selection	934:953	ingredient selection	934:953	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	3	48	theme	0.88	657:660	arg1	range					640:644	the range	636:644	the range of 0.43 to 0.88	636:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	0	49	gly	heterogeneity	30:42	arg1	arabinoxylan					47:58	arabinoxylan	47:58	arabinoxylan	47:58	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	50	from	set	370:372	arg1	AX					362:363	AX	362:363	AX	362:363	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	6	51	theme	structural	1034:1043	arg1	heterogeneity					1045:1057	structural heterogeneity	1034:1057	structural heterogeneity	1034:1057	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
36746587	1	52	theme	arabinoxylan	140:151	arg1	impact					130:135	The impact	126:135	The impact of arabinoxylan (AX) on the brewing process and beer characteristics	126:204	The impact of arabinoxylan (AX) on the brewing process and beer characteristics depends on its content and structure and is often overlooked in research and industry.					
36746587	0	53	theme	pilsner	74:80	arg1	beers					82:86	commercial pilsner beers	63:86	commercial pilsner beers	63:86	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	54	dep	occurrence	4:13	arg1	The					0:2	The	0:2	The	0:2	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	2	55	theme	AX	362:363	arg1	beers					396:400	AX in a set of commercial pilsner beers	362:400	AX in a set of commercial pilsner beers	362:400	This paper reports on the occurrence and structural heterogeneity of AX in a set of commercial pilsner beers and their non-alcoholic counterparts.					
36746587	0	56	theme	commercial	63:72	arg1	beers					82:86	commercial pilsner beers	63:86	commercial pilsner beers	63:86	The occurrence and structural heterogeneity of arabinoxylan in commercial pilsner beers and their non-alcoholic counterparts.					
36746587	3	57	theme	average	602:608	arg1	degree					610:615	an average degree	599:615	an average degree of substitution in the range of 0.43 to 0.88	599:660	Fractionation by graded ethanol precipitation allowed us to isolate AX-rich fractions from beer with a number-average degree of polymerisation of 4 to 308 and an average degree of substitution in the range of 0.43 to 0.88.					
36746587	6	58	theme	AX	1019:1020	arg1	content					1022:1028	AX content	1019:1028	AX content	1019:1028	By comparing the chemical composition of the beers, differences in beer production methods and ingredient selection were deduced and used to tentatively explain the differences in AX content and structural heterogeneity.					
37005456	5	0	theme	inflammatory	762:773	arg1	microenvironment					786:801	an inflammatory intestinal microenvironment	759:801	an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines	759:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	6	1	theme	WT	1002:1003	arg1	mice					1005:1008	WT mice	1002:1008	WT mice	1002:1008	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	1	2	theme	innate	138:143	arg1	responses					152:160	innate immune responses	138:160	innate immune responses	138:160	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	5	3	theme	intestinal	775:784	arg1	microenvironment					786:801	an inflammatory intestinal microenvironment	759:801	an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines	759:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	7	4	theme	inflammatory	1162:1173	arg1	microenvironment					1179:1194	an inflammatory gut microenvironment	1159:1194	an inflammatory gut microenvironment	1159:1194	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	9	5	theme	microbiota	1490:1499	arg1	diseases					1519:1526	diverse microbiota dysbiosis-related diseases	1482:1526	diverse microbiota dysbiosis-related diseases	1482:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	1	6	theme	immune	145:150	arg1	responses					152:160	innate immune responses	138:160	innate immune responses	138:160	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	9	7	theme	prophylactic	1444:1455	arg1	target					1472:1477	the prophylactic or therapeutic target	1440:1477	the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases	1440:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	5	8	contain	had	755:757	arg1	mice					745:748	Axl-/- mice	738:748	Axl-/- mice	738:748	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	5	8	contain	had	755:757	arg2	microenvironment					786:801	an inflammatory intestinal microenvironment	759:801	an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines	759:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	6	9	theme	DSS-induced	898:908	arg1	colitis					910:916	DSS-induced colitis	898:916	DSS-induced colitis	898:916	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	3	10	theme	gut	512:514	arg1	microbiota					516:525	the gut microbiota	508:525	the gut microbiota	508:525	In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics.					
37005456	5	11	theme	Axl-/-	738:743	arg1	mice					745:748	Axl-/- mice	738:748	Axl-/- mice	738:748	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	4	12	with	consistent	696:705	arg1	mice					732:735	DSS-induced colitis mice	712:735	DSS-induced colitis mice	712:735	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	7	13	with	conjunction	1142:1152	arg1	microenvironment					1179:1194	an inflammatory gut microenvironment	1159:1194	an inflammatory gut microenvironment	1159:1194	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	4	14	theme	colitis	724:730	arg1	mice					732:735	DSS-induced colitis mice	712:735	DSS-induced colitis mice	712:735	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	7	15	theme	microbiota	1128:1137	arg1	compositions					1104:1115	aberrant compositions	1095:1115	aberrant compositions of the gut microbiota	1095:1137	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	5	16	theme	cytokines	874:882	arg1	overexpression					843:856	overexpression	843:856	overexpression of inflammatory cytokines	843:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	5	16	theme	cytokines	874:882	arg1	peptides					830:837	reduced antimicrobial peptides	808:837	reduced antimicrobial peptides	808:837	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	5	17	with	microenvironment	786:801	arg1	overexpression					843:856	overexpression	843:856	overexpression of inflammatory cytokines	843:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	5	17	with	microenvironment	786:801	arg1	peptides					830:837	reduced antimicrobial peptides	808:837	reduced antimicrobial peptides	808:837	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	2	18	theme	composition	348:358	arg1	regulation					319:328	the regulation	315:328	the regulation of gut microbiota composition	315:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	8	19	theme	colitis	1290:1296	arg1	pathogenesis					1274:1285	the pathogenesis	1270:1285	the pathogenesis of colitis	1270:1296	In conclusion, the data demonstrated that Axl signaling could ameliorate the pathogenesis of colitis by preventing dysbiosis of gut microbiota.					
37005456	4	20	theme	DSS	565:567	arg1	administration					569:582	DSS administration	565:582	DSS administration	565:582	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	3	21	theme	DSS-induced	405:415	arg1	colitis					417:423	DSS-induced colitis	405:423	DSS-induced colitis	405:423	In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics.					
37005456	6	22	from	expansion	951:959	arg1	mice					989:992	Axl-/- mice	982:992	Axl-/- mice	982:992	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	4	23	from	abundant	651:658	arg1	patients					663:670	patients	663:670	patients with IBD	663:679	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	1	24	theme	inflammatory	166:177	arg1	IBD					194:196	IBD	194:196	IBD	194:196	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	24	theme	inflammatory	166:177	arg1	disease					185:191	inflammatory bowel disease	166:191	inflammatory bowel disease (IBD)	166:197	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	9	25	theme	potential	1369:1377	arg1	biomarker					1385:1393	a potential novel biomarker	1367:1393	a potential novel biomarker for IBD	1367:1401	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	9	25	theme	potential	1369:1377	arg1	Axl					1352:1354	Axl	1352:1354	Axl	1352:1354	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	7	26	theme	gut	1124:1126	arg1	microbiota					1128:1137	the gut microbiota	1120:1137	the gut microbiota	1120:1137	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	2	27	theme	microbiota	337:346	arg1	composition					348:358	gut microbiota composition	333:358	gut microbiota composition	333:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	9	28	theme	novel	1379:1383	arg1	biomarker					1385:1393	a potential novel biomarker	1367:1393	a potential novel biomarker for IBD	1367:1401	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	9	28	theme	novel	1379:1383	arg1	Axl					1352:1354	Axl	1352:1354	Axl	1352:1354	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	2	29	theme	Axl	276:278	arg1	role					268:271	the role	264:271	the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition	264:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	9	30	theme	diverse	1482:1488	arg1	diseases					1519:1526	diverse microbiota dysbiosis-related diseases	1482:1526	diverse microbiota dysbiosis-related diseases	1482:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	3	31	theme	increased	432:440	arg1	expression					446:455	increased Axl expression	432:455	increased Axl expression	432:455	In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics.					
37005456	0	32	theme	DSS-induced	15:25	arg1	colitis					27:33	DSS-induced colitis	15:33	DSS-induced colitis	15:33	Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota.					
37005456	4	33	theme	Axl-/-	545:550	arg1	mice					552:555	Axl-/- mice	545:555	Axl-/- mice without DSS administration	545:582	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	6	34	theme	colitis	910:916	arg1	onset					889:893	The onset	885:893	The onset of DSS-induced colitis	885:916	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	1	35	theme	kinase	96:101	arg1	receptor					103:110	a tyrosine kinase receptor	85:110	a tyrosine kinase receptor	85:110	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	35	theme	kinase	96:101	arg1	Axl					78:80	Axl	78:80	Axl	78:80	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	35	theme	kinase	96:101	arg1	regulator					124:132	a negative regulator	113:132	a negative regulator for innate immune responses and inflammatory bowel disease (IBD)	113:197	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	9	36	theme	therapeutic	1460:1470	arg1	target					1472:1477	the prophylactic or therapeutic target	1440:1477	the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases	1440:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	3	37	theme	Axl	442:444	arg1	expression					446:455	increased Axl expression	432:455	increased Axl expression	432:455	In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics.					
37005456	4	38	from	patients	663:670	arg1	abundant					651:658	abundant	651:658	abundant	651:658	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	4	39	with	patients	663:670	arg1	IBD					677:679	IBD	677:679	IBD	677:679	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	1	40	theme	bowel	179:183	arg1	IBD					194:196	IBD	194:196	IBD	194:196	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	40	theme	bowel	179:183	arg1	disease					185:191	inflammatory bowel disease	166:191	inflammatory bowel disease (IBD)	166:197	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	7	41	theme	gut	1175:1177	arg1	microenvironment					1179:1194	an inflammatory gut microenvironment	1159:1194	an inflammatory gut microenvironment	1159:1194	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	7	42	theme	aberrant	1095:1102	arg1	compositions					1104:1115	aberrant compositions	1095:1115	aberrant compositions of the gut microbiota	1095:1137	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	8	43	theme	microbiota	1329:1338	arg1	dysbiosis					1312:1320	dysbiosis	1312:1320	dysbiosis of gut microbiota	1312:1338	In conclusion, the data demonstrated that Axl signaling could ameliorate the pathogenesis of colitis by preventing dysbiosis of gut microbiota.					
37005456	2	44	theme	gut	204:206	arg1	microbiota					208:217	The gut microbiota	200:217	The gut microbiota	200:217	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	8	45	theme	gut	1325:1327	arg1	microbiota					1329:1338	gut microbiota	1325:1338	gut microbiota	1325:1338	In conclusion, the data demonstrated that Axl signaling could ameliorate the pathogenesis of colitis by preventing dysbiosis of gut microbiota.					
37005456	5	46	theme	reduced	808:814	arg1	peptides					830:837	reduced antimicrobial peptides	808:837	reduced antimicrobial peptides	808:837	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	7	47	theme	Axl	1049:1051	arg1	signaling					1053:1061	Axl signaling	1049:1061	Axl signaling	1049:1061	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	4	48	theme	DSS-induced	712:722	arg1	colitis					724:730	DSS-induced colitis	712:730	DSS-induced colitis mice	712:735	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	5	49	theme	antimicrobial	816:828	arg1	peptides					830:837	reduced antimicrobial peptides	808:837	reduced antimicrobial peptides	808:837	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	6	50	theme	Axl-/-	982:987	arg1	mice					989:992	Axl-/- mice	982:992	Axl-/- mice	982:992	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	3	51	with	mice	395:398	arg1	colitis					417:423	DSS-induced colitis	405:423	DSS-induced colitis	405:423	In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics.					
37005456	9	52	theme	diseases	1519:1526	arg1	target					1472:1477	the prophylactic or therapeutic target	1440:1477	the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases	1440:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	2	53	theme	IBD	303:305	arg1	pathogenesis					287:298	the pathogenesis	283:298	the pathogenesis of IBD through the regulation of gut microbiota composition	283:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	7	54	theme	signaling	1053:1061	arg1	lack					1041:1044	a lack	1039:1044	a lack of Axl signaling	1039:1061	These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment.					
37005456	9	55	theme	dysbiosis-related	1501:1517	arg1	diseases					1519:1526	diverse microbiota dysbiosis-related diseases	1482:1526	diverse microbiota dysbiosis-related diseases	1482:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	1	56	theme	tyrosine	87:94	arg1	receptor					103:110	a tyrosine kinase receptor	85:110	a tyrosine kinase receptor	85:110	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	56	theme	tyrosine	87:94	arg1	Axl					78:80	Axl	78:80	Axl	78:80	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	56	theme	tyrosine	87:94	arg1	regulator					124:132	a negative regulator	113:132	a negative regulator for innate immune responses and inflammatory bowel disease (IBD)	113:197	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	4	57	theme	increased	594:602	arg1	Proteobacteria					636:649	the Proteobacteria	632:649	the Proteobacteria abundant in patients with IBD	632:679	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	4	57	theme	increased	594:602	arg1	loads					614:618	increased bacterial loads	594:618	increased bacterial loads	594:618	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	2	58	theme	immune	240:245	arg1	homeostasis					247:257	intestinal immune homeostasis	229:257	intestinal immune homeostasis	229:257	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	1	59	theme	negative	115:122	arg1	receptor					103:110	a tyrosine kinase receptor	85:110	a tyrosine kinase receptor	85:110	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	1	59	theme	negative	115:122	arg1	regulator					124:132	a negative regulator	113:132	a negative regulator for innate immune responses and inflammatory bowel disease (IBD)	113:197	Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD).					
37005456	2	60	from	role	268:271	arg1	pathogenesis					287:298	the pathogenesis	283:298	the pathogenesis of IBD through the regulation of gut microbiota composition	283:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	9	61	theme	potential	1416:1424	arg1	candidate					1426:1434	a potential candidate	1414:1434	a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases	1414:1526	Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.					
37005456	0	62	theme	microbiota	66:75	arg1	dysbiosis					49:57	dysbiosis	49:57	dysbiosis of gut microbiota	49:75	Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota.					
37005456	2	63	theme	intestinal	229:238	arg1	homeostasis					247:257	intestinal immune homeostasis	229:257	intestinal immune homeostasis	229:257	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	5	64	theme	inflammatory	861:872	arg1	cytokines					874:882	inflammatory cytokines	861:882	inflammatory cytokines	861:882	Axl-/- mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines.					
37005456	2	65	theme	gut	333:335	arg1	composition					348:358	gut microbiota composition	333:358	gut microbiota composition	333:358	The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved.					
37005456	4	66	theme	abundant	651:658	arg1	Proteobacteria					636:649	the Proteobacteria	632:649	the Proteobacteria abundant in patients with IBD	632:679	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	4	66	theme	abundant	651:658	arg1	loads					614:618	increased bacterial loads	594:618	increased bacterial loads	594:618	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	6	67	theme	abnormal	942:949	arg1	expansion					951:959	an abnormal expansion	939:959	an abnormal expansion of Proteobacteria in Axl-/- mice	939:992	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	0	68	theme	gut	62:64	arg1	microbiota					66:75	gut microbiota	62:75	gut microbiota	62:75	Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota.					
37005456	6	69	theme	Proteobacteria	964:977	arg1	expansion					951:959	an abnormal expansion	939:959	an abnormal expansion of Proteobacteria in Axl-/- mice	939:992	The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl-/- mice than in WT mice.					
37005456	8	70	theme	Axl	1239:1241	arg1	signaling					1243:1251	Axl signaling	1239:1251	Axl signaling	1239:1251	In conclusion, the data demonstrated that Axl signaling could ameliorate the pathogenesis of colitis by preventing dysbiosis of gut microbiota.					
37005456	4	71	theme	bacterial	604:612	arg1	Proteobacteria					636:649	the Proteobacteria	632:649	the Proteobacteria abundant in patients with IBD	632:679	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37005456	4	71	theme	bacterial	604:612	arg1	loads					614:618	increased bacterial loads	594:618	increased bacterial loads	594:618	Axl-/- mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice.					
37072057	5	0	theme	molecular	1032:1040	arg1	chain					1042:1046	the CS molecular chain	1025:1046	the CS molecular chain	1025:1046	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	4	1	theme	DES/lignin	826:835	arg1	complex					837:843	the DES/lignin complex	822:843	the DES/lignin complex	822:843	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	3	2	theme	film	711:714	arg1	times					690:694	12.5 times	685:694	12.5 times that of the CS film	685:714	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	3	2	theme	film	711:714	arg1	film					670:673	the plasticized film	654:673	the plasticized film	654:673	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	2	3	theme	DES/lignin	435:444	arg1	effect					420:425	the toughening effect	405:425	the toughening effect of this DES/lignin on a CS film substrate	405:467	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	5	4	theme	chain	1042:1046	arg1	rigidity					1013:1020	the rigidity	1009:1020	the rigidity of the CS molecular chain	1009:1046	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	1	5	from	shells	147:152	arg1	biopolymer					126:135	a natural biopolymer	116:135	a natural biopolymer from crab shells known for its biocompatibility and biodegradability	116:204	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	1	5	from	shells	147:152	arg1	Chitosan					99:106	Chitosan	99:106	Chitosan (CS)	99:111	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	4	6	theme	hydrogen	985:992	arg1	bonding					994:1000	hydrogen bonding	985:1000	hydrogen bonding	985:1000	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	3	7	theme	break	634:638	arg1	%					648:648	break of 62.6 %	634:648	break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film	634:714	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	5	8	theme	broader	1267:1273	arg1	utilization					1275:1285	the broader utilization	1263:1285	the broader utilization of CS films	1263:1297	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	4	9	theme	hydrogen	877:884	arg1	bonds					886:890	the hydrogen bonds	873:890	the hydrogen bonds between the CS molecules	873:915	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	2	10	from	effect	420:425	arg1	substrate					459:467	a CS film substrate	449:467	a CS film substrate	449:467	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	3	11	theme	plasticized	658:668	arg1	times					690:694	12.5 times	685:694	12.5 times that of the CS film	685:714	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	3	11	theme	plasticized	658:668	arg1	film					670:673	the plasticized film	654:673	the plasticized film	654:673	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	4	12	theme	nuclear	761:767	arg1	resonance					778:786	nuclear magnetic resonance	761:786	nuclear magnetic resonance	761:786	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	4	13	theme	CS	968:969	arg1	molecules					971:979	the CS molecules	964:979	the CS molecules	964:979	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	2	14	theme	deep	371:374	arg1	solvents					385:392	deep eutectic solvents	371:392	deep eutectic solvents (DES)	371:398	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	2	14	theme	deep	371:374	arg1	DES					395:397	DES	395:397	DES	395:397	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	2	15	theme	film	454:457	arg1	substrate					459:467	a CS film substrate	449:467	a CS film substrate	449:467	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	5	16	theme	CS	1029:1030	arg1	chain					1042:1046	the CS molecular chain	1025:1046	the CS molecular chain	1025:1046	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	4	17	theme	CS	904:905	arg1	molecules					907:915	the CS molecules	900:915	the CS molecules	900:915	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	0	18	theme	chitosan	83:90	arg1	films					92:96	chitosan films	83:96	chitosan films	83:96	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	2	19	theme	composite	293:301	arg1	films					303:307	CS composite films	290:307	CS composite films	290:307	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	3	20	dep	times	690:694	arg1	that					696:699	that	696:699	that	696:699	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	2	21	theme	lignin	361:366	arg1	dissolution					346:356	the selective dissolution	332:356	the selective dissolution of lignin by deep eutectic solvents (DES)	332:398	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	5	22	theme	plasticized	1074:1084	arg1	film					1089:1092	a plasticized CS film	1072:1092	a plasticized CS film	1072:1092	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	4	23	theme	magnetic	769:776	arg1	resonance					778:786	nuclear magnetic resonance	761:786	nuclear magnetic resonance	761:786	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	2	24	theme	CS	290:291	arg1	films					303:307	CS composite films	290:307	CS composite films	290:307	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	5	25	theme	CS	1086:1087	arg1	film					1089:1092	a plasticized CS film	1072:1092	a plasticized CS film	1072:1092	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	4	26	dep	spectroscopy	744:755	arg1	analyses					788:795	analyses	788:795	analyses	788:795	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	0	27	theme	plasticizing	16:27	arg1	mechanism					29:37	plasticizing mechanism	16:37	plasticizing mechanism	16:37	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	3	28	theme	film	597:600	arg1	plasticity					576:585	the plasticity	572:585	the plasticity of the CS film	572:600	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	4	29	dep	interacted	845:854	arg1	recombined					948:957	recombined	948:957	recombined with the CS molecules via hydrogen bonding	948:1000	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	0	30	theme	deep	42:45	arg1	solvent/lignin					56:69	deep eutectic solvent/lignin	42:69	deep eutectic solvent/lignin	42:69	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	3	31	theme	DES/lignin	539:548	arg1	addition					527:534	The addition	523:534	The addition of DES/lignin	523:548	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	4	32	dep	transform	725:733	arg1	infrared					735:742	infrared	735:742	transform infrared spectroscopy and nuclear magnetic resonance analyses	725:795	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	2	33	theme	eutectic	376:383	arg1	solvents					385:392	deep eutectic solvents	371:392	deep eutectic solvents (DES)	371:398	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	2	33	theme	eutectic	376:383	arg1	DES					395:397	DES	395:397	DES	395:397	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	0	34	theme	solvent/lignin	56:69	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	0	34	theme	solvent/lignin	56:69	arg1	mechanism					29:37	plasticizing mechanism	16:37	plasticizing mechanism	16:37	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	3	35	theme	CS	594:595	arg1	film					597:600	the CS film	590:600	the CS film	590:600	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	0	36	theme	eutectic	47:54	arg1	solvent/lignin					56:69	deep eutectic solvent/lignin	42:69	deep eutectic solvent/lignin	42:69	Preparation and plasticizing mechanism of deep eutectic solvent/lignin plasticized chitosan films.					
37072057	4	37	from	molecules	809:817	arg1	complex					837:843	the DES/lignin complex	822:843	the DES/lignin complex	822:843	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	3	38	theme	maximum	612:618	arg1	elongation					620:629	a maximum elongation	610:629	a maximum elongation	610:629	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	5	39	theme	CS	1290:1291	arg1	films					1293:1297	CS films	1290:1297	CS films	1290:1297	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	5	40	theme	CS	1183:1184	arg1	films					1186:1190	CS films	1183:1190	CS films	1183:1190	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	5	41	theme	films	1293:1297	arg1	utilization					1275:1285	the broader utilization	1263:1285	the broader utilization of CS films	1263:1297	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	1	42	theme	natural	118:124	arg1	biopolymer					126:135	a natural biopolymer	116:135	a natural biopolymer from crab shells known for its biocompatibility and biodegradability	116:204	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	1	42	theme	natural	118:124	arg1	Chitosan					99:106	Chitosan	99:106	Chitosan (CS)	99:111	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	5	43	theme	films	1186:1190	arg1	toughness					1170:1178	the toughness	1166:1178	the toughness of CS films	1166:1190	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	1	44	theme	CS	216:217	arg1	films					219:223	CS films	216:223	CS films	216:223	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	2	45	theme	corresponding	498:510	arg1	mechanism					512:520	its corresponding mechanism	494:520	its corresponding mechanism	494:520	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	1	46	theme	crab	142:145	arg1	shells					147:152	crab shells	142:152	crab shells	142:152	Chitosan (CS) is a natural biopolymer from crab shells known for its biocompatibility and biodegradability; however, CS films are extremely rigid, limiting their applications.					
37072057	2	47	theme	toughening	409:418	arg1	effect					420:425	the toughening effect	405:425	the toughening effect of this DES/lignin on a CS film substrate	405:467	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	5	48	theme	DES/regenerated	1132:1146	arg1	lignin					1148:1153	DES/regenerated lignin	1132:1153	DES/regenerated lignin	1132:1153	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	2	49	theme	CS	451:452	arg1	substrate					459:467	a CS film substrate	449:467	a CS film substrate	449:467	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	4	50	dep	Fourier	717:723	arg1	transform					725:733	transform	725:733	transform infrared spectroscopy and nuclear magnetic resonance analyses	725:795	Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses showed that molecules in the DES/lignin complex interacted with CS to break the hydrogen bonds between the CS molecules; simultaneously, each molecule recombined with the CS molecules via hydrogen bonding.					
37072057	5	51	theme	lignin	1148:1153	arg1	ability					1121:1127	the ability	1117:1127	the ability of DES/regenerated lignin to improve the toughness of CS films	1117:1190	Thus, the rigidity of the CS molecular chain was weakened to achieve a plasticized CS film, thereby demonstrating the ability of DES/regenerated lignin to improve the toughness of CS films, which provides a reference for modifying plasticity and could lead to the broader utilization of CS films.					
37072057	3	52	theme	of	640:641	arg1	%					648:648	break of 62.6 %	634:648	break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film	634:714	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
37072057	2	53	theme	selective	336:344	arg1	dissolution					346:356	the selective dissolution	332:356	the selective dissolution of lignin by deep eutectic solvents (DES)	332:398	In this study, CS composite films were prepared based on the selective dissolution of lignin by deep eutectic solvents (DES), and the toughening effect of this DES/lignin on a CS film substrate was examined, along with its corresponding mechanism.					
37072057	3	54	theme	CS	708:709	arg1	film					711:714	the CS film	704:714	the CS film	704:714	The addition of DES/lignin effectively increased the plasticity of the CS film, giving a maximum elongation at break of 62.6 % for the plasticized film, which is 12.5 times that of the CS film.					
35500851	8	0	theme	germination	1134:1144	arg1	test					1146:1149	a germination test	1132:1149	a germination test	1132:1149	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	6	1	theme	EFB	851:853	arg1	ACNPs					855:859	EFB ACNPs	851:859	EFB ACNPs	851:859	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	2	2	used	used	323:326	arg2	Nanofertilizers					257:271	Nanofertilizers	257:271	Nanofertilizers derived from chitosan and oil palm biomass	257:314	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	4	3	theme	lignocellulose	635:648	arg1	LCNFs					662:666	LCNFs	662:666	LCNFs	662:666	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	3	theme	lignocellulose	635:648	arg1	nanofibers					650:659	lignocellulose nanofibers	635:659	lignocellulose nanofibers (LCNFs)	635:667	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	7	4	theme	good	1091:1094	arg1	dispersion					1096:1105	good dispersion	1091:1105	good dispersion	1091:1105	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	6	5	theme	pore	832:835	arg1	volume					837:842	pore volume	832:842	pore volume	832:842	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	12	6	theme	tropical	1899:1906	arg1	areas					1908:1912	tropical areas	1899:1912	tropical areas	1899:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	11	7	theme	synergetic	1711:1720	arg1	effect					1737:1742	a synergetic biofertilizing effect	1709:1742	a synergetic biofertilizing effect	1709:1742	All chitosan nanocomposites had a synergetic biofertilizing effect on fungi and mycorrhiza.					
35500851	7	8	theme	formation	1080:1088	arg1	lack					1045:1048	the lack	1041:1048	the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility	1041:1126	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	2	9	theme	paddy	339:343	arg1	growth					345:350	paddy growth	339:350	paddy growth	339:350	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	1	10	theme	paddy	215:219	arg1	plants					221:226	paddy plants	215:226	paddy plants using paludiculture systems	215:254	Indonesia has committed to restoring degraded peatlands by revegetating them with paddy plants using paludiculture systems.					
35500851	8	11	theme	growth	1194:1199	arg1	patterns					1201:1208	the best growth patterns	1185:1208	the best growth patterns for the Dendang paddy variety	1185:1238	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	8	12	contain	had	1291:1293	arg2	patterns					1311:1318	the best growth patterns	1295:1318	the best growth patterns for the Indragiri paddy variety	1295:1350	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	8	12	contain	had	1291:1293	arg1	nanocomposites					1276:1289	the nanocomposites	1272:1289	the nanocomposites	1272:1289	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	4	13	theme	Chitosan	476:483	arg1	nanocomposites					485:498	Chitosan nanocomposites	476:498	Chitosan nanocomposites	476:498	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	3	14	theme	tropical	457:464	arg1	peatland					466:473	tropical peatland	457:473	tropical peatland	457:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	8	15	theme	greenhouse	1255:1264	arg1	test					1266:1269	a greenhouse test	1253:1269	a greenhouse test	1253:1269	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	8	16	theme	Dendang	1218:1224	arg1	variety					1232:1238	the Dendang paddy variety	1214:1238	the Dendang paddy variety	1214:1238	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	6	17	dep	ACNPs	855:859	arg1	followed					862:869	followed	862:869	followed by OPT LCNFs and EFB n-ACNPs	862:898	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	2	18	theme	oil	299:301	arg1	biomass					308:314	oil palm biomass	299:314	oil palm biomass	299:314	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	7	19	theme	%	1002:1002	arg1	average					986:992	an average	983:992	an average of 45.77% and 34.00%, respectively	983:1027	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	9	20	theme	maximum	1474:1480	arg1	potential					1489:1497	highest maximum growth potential	1466:1497	highest maximum growth potential (100.00%)	1466:1507	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	20	theme	maximum	1474:1480	arg1	%					1506:1506	100.00%	1500:1506	100.00%	1500:1506	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	1	21	theme	degraded	170:177	arg1	peatlands					179:187	degraded peatlands	170:187	degraded peatlands	170:187	Indonesia has committed to restoring degraded peatlands by revegetating them with paddy plants using paludiculture systems.					
35500851	4	22	theme	activated	546:554	arg1	ACNPs					578:582	ACNPs	578:582	ACNPs	578:582	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	22	theme	activated	546:554	arg1	nanoparticles					563:575	activated carbon nanoparticles	546:575	activated carbon nanoparticles (ACNPs)	546:583	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	8	23	dep	nanocomposites	1161:1174	arg1	provided					1176:1183	provided	1176:1183	provided the best growth patterns for the Dendang paddy variety	1176:1238	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	8	24	theme	growth	1304:1309	arg1	patterns					1311:1318	the best growth patterns	1295:1318	the best growth patterns for the Indragiri paddy variety	1295:1350	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	11	25	theme	chitosan	1681:1688	arg1	nanocomposites					1690:1703	All chitosan nanocomposites	1677:1703	All chitosan nanocomposites	1677:1703	All chitosan nanocomposites had a synergetic biofertilizing effect on fungi and mycorrhiza.					
35500851	12	26	theme	peatland	1831:1838	arg1	varieties					1846:1854	peatland paddy varieties	1831:1854	peatland paddy varieties	1831:1854	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	3	27	theme	growth	387:392	arg1	media					394:398	the potential growth media	373:398	the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland	373:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	0	28	theme	peatland	111:118	arg1	seeds					126:130	peatland paddy seeds	111:130	peatland paddy seeds	111:130	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	8	29	theme	Indragiri	1328:1336	arg1	variety					1344:1350	the Indragiri paddy variety	1324:1350	the Indragiri paddy variety	1324:1350	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	3	30	theme	nanocomposite	412:424	arg1	films					426:430	chitosan nanocomposite films	403:430	chitosan nanocomposite films for paddy seeds grown in tropical peatland	403:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	10	31	theme	palm	1586:1589	arg1	n-ACNPs					1597:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	7	32	theme	elastic	943:949	arg1	modulus					951:957	elastic modulus	943:957	elastic modulus value	943:963	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	9	33	theme	height	1522:1527	arg1	11.27 cm					1538:1545	11.27 cm	1538:1545	11.27 cm	1538:1545	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	33	theme	height	1522:1527	arg1	average					1529:1535	highest height average	1514:1535	highest height average (11.27 cm)	1514:1546	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	4	34	theme	carbon	599:604	arg1	nanoparticles					606:618	nonactivated carbon nanoparticles	586:618	nonactivated carbon nanoparticles (n-ACNPs)	586:628	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	34	theme	carbon	599:604	arg1	n-ACNPs					621:627	n-ACNPs	621:627	n-ACNPs	621:627	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	10	35	theme	growth	1626:1631	arg1	natality					1633:1640	the highest growth natality	1614:1640	the highest growth natality (16.44%)	1614:1649	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	10	35	theme	growth	1626:1631	arg1	%					1648:1648	16.44%	1643:1648	16.44%	1643:1648	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	0	36	theme	chitosan/carbon	13:27	arg1	nanoparticles					29:41	chitosan/carbon nanoparticles	13:41	chitosan/carbon nanoparticles	13:41	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	6	37	theme	EFB	888:890	arg1	n-ACNPs					892:898	EFB n-ACNPs	888:898	EFB n-ACNPs	888:898	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	5	38	contain	have	745:748	arg2	tendency					752:759	a tendency	750:759	a tendency to aggregate	750:772	All carbon nanoparticles were reversibly aggregated, whereas LCNFs did not have a tendency to aggregate but were entangled.					
35500851	5	38	contain	have	745:748	arg1	LCNFs					731:735	LCNFs	731:735	LCNFs	731:735	All carbon nanoparticles were reversibly aggregated, whereas LCNFs did not have a tendency to aggregate but were entangled.					
35500851	0	39	theme	nanofiber	71:79	arg1	composite					81:89	chitosan/lignocellulose nanofiber composite	47:89	chitosan/lignocellulose nanofiber composite	47:89	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	12	40	from	restoration	1884:1894	arg1	areas					1908:1912	tropical areas	1899:1912	tropical areas	1899:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	9	41	theme	fruit	1368:1372	arg1	nanocomposites					1385:1398	Chitosan/empty fruit bunch ACNP nanocomposites	1353:1398	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator	1353:1420	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	12	42	theme	Chitosan	1769:1776	arg1	regulator					1817:1825	a growth regulator	1808:1825	a growth regulator	1808:1825	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	42	theme	Chitosan	1769:1776	arg1	nanocomposites					1778:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	42	theme	Chitosan	1769:1776	arg1	restoration					1884:1894	peatland restoration	1875:1894	peatland restoration in tropical areas	1875:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	7	43	theme	tensile	922:928	arg1	strength					930:937	nanocomposites' tensile strength	906:937	nanocomposites' tensile strength	906:937	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	9	44	theme	ACNP	1380:1383	arg1	nanocomposites					1385:1398	Chitosan/empty fruit bunch ACNP nanocomposites	1353:1398	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator	1353:1420	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	5	45	theme	carbon	674:679	arg1	nanoparticles					681:693	All carbon nanoparticles	670:693	All carbon nanoparticles	670:693	All carbon nanoparticles were reversibly aggregated, whereas LCNFs did not have a tendency to aggregate but were entangled.					
35500851	6	46	dep	specific	806:813	arg1	highest					798:804	highest	798:804	highest	798:804	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	8	47	theme	paddy	1226:1230	arg1	variety					1232:1238	the Dendang paddy variety	1214:1238	the Dendang paddy variety	1214:1238	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	7	48	theme	micro-aggregates	1063:1078	arg1	formation					1080:1088	micro-aggregates formation	1063:1088	micro-aggregates formation	1063:1088	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	9	49	theme	highest	1430:1436	arg1	normality					1445:1453	the highest growth normality	1426:1453	the highest growth normality (100.00%)	1426:1463	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	49	theme	highest	1430:1436	arg1	%					1462:1462	100.00%	1456:1462	100.00%	1456:1462	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	11	50	theme	biofertilizing	1722:1735	arg1	effect					1737:1742	a synergetic biofertilizing effect	1709:1742	a synergetic biofertilizing effect	1709:1742	All chitosan nanocomposites had a synergetic biofertilizing effect on fungi and mycorrhiza.					
35500851	7	51	theme	nano-	1053:1057	arg1	lack					1045:1048	the lack	1041:1048	the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility	1041:1126	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	6	52	theme	surface	815:821	arg1	area					823:826	The highest specific surface area	794:826	The highest specific surface area	794:826	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	8	53	theme	best	1189:1192	arg1	patterns					1201:1208	the best growth patterns	1185:1208	the best growth patterns for the Dendang paddy variety	1185:1238	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	9	54	theme	growth	1438:1443	arg1	normality					1445:1453	the highest growth normality	1426:1453	the highest growth normality (100.00%)	1426:1463	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	54	theme	growth	1438:1443	arg1	%					1462:1462	100.00%	1456:1462	100.00%	1456:1462	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	1	55	theme	paludiculture	234:246	arg1	systems					248:254	paludiculture systems	234:254	paludiculture systems	234:254	Indonesia has committed to restoring degraded peatlands by revegetating them with paddy plants using paludiculture systems.					
35500851	10	56	theme	greenhouse	1556:1565	arg1	test					1567:1570	the greenhouse test	1552:1570	the greenhouse test	1552:1570	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	12	57	theme	peatland	1875:1882	arg1	regulator					1817:1825	a growth regulator	1808:1825	a growth regulator	1808:1825	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	57	theme	peatland	1875:1882	arg1	restoration					1884:1894	peatland restoration	1875:1894	peatland restoration in tropical areas	1875:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	57	theme	peatland	1875:1882	arg1	nanocomposites					1778:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	2	58	theme	palm	303:306	arg1	biomass					308:314	oil palm biomass	299:314	oil palm biomass	299:314	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	7	59	theme	%	1013:1013	arg1	average					986:992	an average	983:992	an average of 45.77% and 34.00%, respectively	983:1027	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	9	60	theme	highest	1466:1472	arg1	potential					1489:1497	highest maximum growth potential	1466:1497	highest maximum growth potential (100.00%)	1466:1507	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	60	theme	highest	1466:1472	arg1	%					1506:1506	100.00%	1500:1506	100.00%	1500:1506	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	0	61	theme	growth	94:99	arg1	media					101:105	growth media	94:105	growth media	94:105	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	9	62	theme	growth	1482:1487	arg1	potential					1489:1497	highest maximum growth potential	1466:1497	highest maximum growth potential (100.00%)	1466:1507	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	62	theme	growth	1482:1487	arg1	%					1506:1506	100.00%	1500:1506	100.00%	1500:1506	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	4	63	theme	carbon	556:561	arg1	ACNPs					578:582	ACNPs	578:582	ACNPs	578:582	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	63	theme	carbon	556:561	arg1	nanoparticles					563:575	activated carbon nanoparticles	546:575	activated carbon nanoparticles (ACNPs)	546:583	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	12	64	theme	paddy	1840:1844	arg1	varieties					1846:1854	peatland paddy varieties	1831:1854	peatland paddy varieties	1831:1854	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	2	65	attach	derived	273:279	arg1	biomass					308:314	oil palm biomass	299:314	oil palm biomass	299:314	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	2	65	attach	derived	273:279	arg1	chitosan					286:293	chitosan	286:293	chitosan	286:293	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	2	65	attach	derived	273:279	arg2	Nanofertilizers					257:271	Nanofertilizers	257:271	Nanofertilizers derived from chitosan and oil palm biomass	257:314	Nanofertilizers derived from chitosan and oil palm biomass can be used to enhance paddy growth.					
35500851	8	66	theme	best	1299:1302	arg1	patterns					1311:1318	the best growth patterns	1295:1318	the best growth patterns for the Indragiri paddy variety	1295:1350	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	0	67	theme	paddy	120:124	arg1	seeds					126:130	peatland paddy seeds	111:130	peatland paddy seeds	111:130	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	9	68	contain	had	1422:1424	arg1	nanocomposites					1385:1398	Chitosan/empty fruit bunch ACNP nanocomposites	1353:1398	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator	1353:1420	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	normality					1445:1453	the highest growth normality	1426:1453	the highest growth normality (100.00%)	1426:1463	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	%					1462:1462	100.00%	1456:1462	100.00%	1456:1462	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	%					1506:1506	100.00%	1500:1506	100.00%	1500:1506	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	potential					1489:1497	highest maximum growth potential	1466:1497	highest maximum growth potential (100.00%)	1466:1507	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	11.27 cm					1538:1545	11.27 cm	1538:1545	11.27 cm	1538:1545	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	68	contain	had	1422:1424	arg2	average					1529:1535	highest height average	1514:1535	highest height average (11.27 cm)	1514:1546	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	12	69	theme	growth	1810:1815	arg1	regulator					1817:1825	a growth regulator	1808:1825	a growth regulator	1808:1825	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	69	theme	growth	1810:1815	arg1	nanocomposites					1778:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	69	theme	growth	1810:1815	arg1	restoration					1884:1894	peatland restoration	1875:1894	peatland restoration in tropical areas	1875:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	3	70	theme	potential	377:385	arg1	media					394:398	the potential growth media	373:398	the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland	373:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	10	71	theme	trunk	1591:1595	arg1	n-ACNPs					1597:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	12	72	used	used	1800:1803	arg2	restoration					1884:1894	peatland restoration	1875:1894	peatland restoration in tropical areas	1875:1912	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	72	used	used	1800:1803	arg2	nanocomposites					1778:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites	1769:1791	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	12	72	used	used	1800:1803	arg2	regulator					1817:1825	a growth regulator	1808:1825	a growth regulator	1808:1825	Chitosan nanocomposites can be used as a growth regulator for peatland paddy varieties and can accelerate peatland restoration in tropical areas.					
35500851	9	73	theme	highest	1514:1520	arg1	11.27 cm					1538:1545	11.27 cm	1538:1545	11.27 cm	1538:1545	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	9	73	theme	highest	1514:1520	arg1	average					1529:1535	highest height average	1514:1535	highest height average (11.27 cm)	1514:1546	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	3	74	theme	films	426:430	arg1	media					394:398	the potential growth media	373:398	the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland	373:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	8	75	theme	paddy	1338:1342	arg1	variety					1344:1350	the Indragiri paddy variety	1324:1350	the Indragiri paddy variety	1324:1350	In a germination test, chitosan nanocomposites provided the best growth patterns for the Dendang paddy variety, whereas, in a greenhouse test, the nanocomposites had the best growth patterns for the Indragiri paddy variety.					
35500851	10	76	theme	chitosan/oil	1573:1584	arg1	n-ACNPs					1597:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	chitosan/oil palm trunk n-ACNPs	1573:1603	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	0	77	theme	nanoparticles	29:41	arg1	Potential					0:8	Potential	0:8	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.	0:131	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	7	78	theme	modulus	951:957	arg1	value					959:963	elastic modulus value	943:963	elastic modulus value	943:963	Both nanocomposites' tensile strength and elastic modulus value were reduced with an average of 45.77% and 34.00%, respectively, because of the lack of nano- and micro-aggregates formation, good dispersion, and incompatibility.					
35500851	3	79	theme	chitosan	403:410	arg1	films					426:430	chitosan nanocomposite films	403:430	chitosan nanocomposite films for paddy seeds grown in tropical peatland	403:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	10	80	theme	highest	1618:1624	arg1	natality					1633:1640	the highest growth natality	1614:1640	the highest growth natality (16.44%)	1614:1649	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	10	80	theme	highest	1618:1624	arg1	%					1648:1648	16.44%	1643:1648	16.44%	1643:1648	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	0	81	theme	chitosan/lignocellulose	47:69	arg1	composite					81:89	chitosan/lignocellulose nanofiber composite	47:89	chitosan/lignocellulose nanofiber composite	47:89	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	6	82	dep	LCNFs	878:882	arg1	OPT					874:876	OPT	874:876	OPT	874:876	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	6	83	theme	specific	806:813	arg1	area					823:826	The highest specific surface area	794:826	The highest specific surface area	794:826	The highest specific surface area and pore volume are on EFB ACNPs, followed by OPT LCNFs and EFB n-ACNPs.					
35500851	0	84	theme	composite	81:89	arg1	Potential					0:8	Potential	0:8	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.	0:131	Potential of chitosan/carbon nanoparticles and chitosan/lignocellulose nanofiber composite as growth media for peatland paddy seeds.					
35500851	3	85	theme	paddy	436:440	arg1	seeds					442:446	paddy seeds	436:446	paddy seeds grown in tropical peatland	436:473	This study analyzed the potential growth media of chitosan nanocomposite films for paddy seeds grown in tropical peatland.					
35500851	4	86	theme	nonactivated	586:597	arg1	nanoparticles					606:618	nonactivated carbon nanoparticles	586:618	nonactivated carbon nanoparticles (n-ACNPs)	586:628	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	86	theme	nonactivated	586:597	arg1	n-ACNPs					621:627	n-ACNPs	621:627	n-ACNPs	621:627	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	9	87	theme	Chitosan/empty	1353:1366	arg1	nanocomposites					1385:1398	Chitosan/empty fruit bunch ACNP nanocomposites	1353:1398	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator	1353:1420	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	4	88	with	chitosan	532:539	arg1	nanoparticles					563:575	activated carbon nanoparticles	546:575	activated carbon nanoparticles (ACNPs)	546:583	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	88	with	chitosan	532:539	arg1	nanoparticles					606:618	nonactivated carbon nanoparticles	586:618	nonactivated carbon nanoparticles (n-ACNPs)	586:628	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	88	with	chitosan	532:539	arg1	nanofibers					650:659	lignocellulose nanofibers	635:659	lignocellulose nanofibers (LCNFs)	635:667	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	88	with	chitosan	532:539	arg1	n-ACNPs					621:627	n-ACNPs	621:627	n-ACNPs	621:627	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	88	with	chitosan	532:539	arg1	ACNPs					578:582	ACNPs	578:582	ACNPs	578:582	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	4	88	with	chitosan	532:539	arg1	LCNFs					662:666	LCNFs	662:666	LCNFs	662:666	Chitosan nanocomposites were synthesized by reinforcing chitosan with activated carbon nanoparticles (ACNPs), nonactivated carbon nanoparticles (n-ACNPs), and lignocellulose nanofibers (LCNFs).					
35500851	9	89	theme	bunch	1374:1378	arg1	nanocomposites					1385:1398	Chitosan/empty fruit bunch ACNP nanocomposites	1353:1398	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator	1353:1420	Chitosan/empty fruit bunch ACNP nanocomposites grown in a germinator had the highest growth normality (100.00%), highest maximum growth potential (100.00%), and highest height average (11.27 cm).					
35500851	11	90	contain	had	1705:1707	arg2	effect					1737:1742	a synergetic biofertilizing effect	1709:1742	a synergetic biofertilizing effect	1709:1742	All chitosan nanocomposites had a synergetic biofertilizing effect on fungi and mycorrhiza.					
35500851	11	90	contain	had	1705:1707	arg1	nanocomposites					1690:1703	All chitosan nanocomposites	1677:1703	All chitosan nanocomposites	1677:1703	All chitosan nanocomposites had a synergetic biofertilizing effect on fungi and mycorrhiza.					
35500851	10	91	theme	growth	1655:1660	arg1	%					1673:1673	65.74%	1668:1673	65.74%	1668:1673	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35500851	10	91	theme	growth	1655:1660	arg1	rate					1662:1665	growth rate	1655:1665	growth rate (65.74%)	1655:1674	In the greenhouse test, chitosan/oil palm trunk n-ACNPs achieved the highest growth natality (16.44%) and growth rate (65.74%).					
35217088	7	0	theme	341 °C	1328:1333	arg1	temperature					1306:1316	a maximum degradation temperature	1284:1316	a maximum degradation temperature (Tmax)	1284:1323	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	0	theme	341 °C	1328:1333	arg1	greater					1351:1357	greater	1351:1357	greater	1351:1357	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	0	theme	341 °C	1328:1333	arg1	Tmax					1319:1322	Tmax	1319:1322	Tmax	1319:1322	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	4	1	theme	Dispersive	786:795	arg1	Spectroscopy					803:814	Energy Dispersive X-ray Spectroscopy	779:814	Energy Dispersive X-ray Spectroscopy	779:814	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	2	theme	resonance	932:940	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	2	theme	resonance	932:940	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	5	3	theme	crystallinity	1072:1084	arg1	index					1086:1090	a crystallinity index	1070:1090	a crystallinity index of 58.5%	1070:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	8	4	theme	prominent	1444:1452	arg1	nanofibers					1429:1438	the nanofibers	1425:1438	the nanofibers	1425:1438	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	8	4	theme	prominent	1444:1452	arg1	alternatives					1454:1465	prominent alternatives	1444:1465	prominent alternatives for synthetic fibers for assorted potential applications	1444:1522	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	6	5	theme	peak	1133:1136	arg1	appearance					1106:1115	The appearance	1102:1115	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra	1102:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	7	6	theme	prepared	1266:1273	arg1	CNFs					1275:1278	The prepared CNFs	1262:1278	The prepared CNFs	1262:1278	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	3	7	theme	oxalic	497:502	arg1	acid					504:507	5% oxalic acid	494:507	5% oxalic acid	494:507	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	3	7	theme	oxalic	497:502	arg1	hydrolysis					482:491	acid hydrolysis	477:491	acid hydrolysis (5% oxalic acid)	477:508	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	8	8	theme	manufacturing	1539:1551	arg1	composites					1559:1568	manufacturing green composites	1539:1568	manufacturing green composites	1539:1568	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	7	9	theme	degradation	1294:1304	arg1	temperature					1306:1316	a maximum degradation temperature	1284:1316	a maximum degradation temperature (Tmax)	1284:1323	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	9	theme	degradation	1294:1304	arg1	greater					1351:1357	greater	1351:1357	greater	1351:1357	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	9	theme	degradation	1294:1304	arg1	Tmax					1319:1322	Tmax	1319:1322	Tmax	1319:1322	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	1	10	dep	husk	223:226	arg1	i.e.					211:214	i.e.	211:214	i.e.	211:214	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	4	11	theme	infrared	616:623	arg1	FTIR					639:642	FTIR	639:642	FTIR	639:642	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	11	theme	infrared	616:623	arg1	EDX					817:819	EDX	817:819	EDX	817:819	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	11	theme	infrared	616:623	arg1	spectroscopy					625:636	infrared spectroscopy	616:636	infrared spectroscopy (FTIR)	616:643	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	12	from	appearance	1106:1115	arg1	spectra					1178:1184	the solid state 13C NMR spectra	1154:1184	the solid state 13C NMR spectra	1154:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	6	12	from	appearance	1106:1115	arg1	89.31 ppm					1141:1149	89.31 ppm	1141:1149	89.31 ppm	1141:1149	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	2	13	theme	non-cellulosic	403:416	arg1	components					418:427	non-cellulosic components	403:427	non-cellulosic components	403:427	Pre-treatments such as mercerisation, steam explosion, and peroxide bleaching (chlorine-free) were applied for the removal of non-cellulosic components.					
35217088	6	14	theme	state	1164:1168	arg1	NMR					1174:1176	the solid state 13C NMR	1154:1176	the solid state 13C NMR spectra	1154:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	4	15	theme	Scanning	671:678	arg1	SEM					701:703	SEM	701:703	SEM	701:703	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	15	theme	Scanning	671:678	arg1	microscopy					689:698	Scanning electron microscopy	671:698	Scanning electron microscopy (SEM)	671:704	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	16	theme	X-ray	646:650	arg1	diffraction					652:662	X-ray diffraction	646:662	X-ray diffraction (XRD)	646:668	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	16	theme	X-ray	646:650	arg1	XRD					665:667	XRD	665:667	XRD	665:667	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	17	theme	cellulose	1224:1232	arg1	phase					1234:1238	the type-I cellulose phase	1213:1238	the type-I cellulose phase	1213:1238	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	5	18	theme	typical	1003:1009	arg1	structure					1028:1036	a typical cellulose type-I structure	1001:1036	a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%	1001:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	1	19	theme	cellulose	156:164	arg1	CNFs					178:181	CNFs	178:181	CNFs	178:181	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	1	19	theme	cellulose	156:164	arg1	nanofibers					166:175	extract cellulose nanofibers	148:175	extract cellulose nanofibers (CNFs)	148:182	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	0	20	theme	millet	100:105	arg1	husk					92:95	waste husk	86:95	waste husk of millet (Pennisetum glaucum)	86:126	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	4	21	theme	Differential	854:865	arg1	calorimetry					876:886	Differential scanning calorimetry	854:886	Differential scanning calorimetry (DSC)	854:892	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	21	theme	Differential	854:865	arg1	DSC					889:891	DSC	889:891	DSC	889:891	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	22	theme	electron	720:727	arg1	TEM					741:743	TEM	741:743	TEM	741:743	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	22	theme	electron	720:727	arg1	microscopy					729:738	Transmission electron microscopy	707:738	Transmission electron microscopy (TEM)	707:744	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	5	23	theme	isolated	982:989	arg1	CNFs					991:994	The isolated CNFs	978:994	The isolated CNFs	978:994	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	0	24	dep	millet	100:105	arg1	glaucum					119:125	Pennisetum glaucum	108:125	Pennisetum glaucum	108:125	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	0	25	theme	Chlorine-free	0:12	arg1	extraction					14:23	Chlorine-free extraction	0:23	Chlorine-free extraction	0:23	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	1	26	theme	agro-waste	241:250	arg1	worthy					252:257	an agro-waste worthy	238:257	an agro-waste worthy of consideration	238:274	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	1	26	theme	agro-waste	241:250	arg1	source					203:208	a sustainable source	189:208	a sustainable source	189:208	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	4	27	theme	magnetic	923:930	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	27	theme	magnetic	923:930	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	3	28	theme	millet	443:448	arg1	pulp					455:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	5	29	theme	10-12 nm	1057:1064	arg1	diameter					1045:1052	a diameter	1043:1052	a diameter of 10-12 nm and a crystallinity index of 58.5%	1043:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	7	30	theme	raw	1364:1366	arg1	RMH					1381:1383	RMH	1381:1383	RMH	1381:1383	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	30	theme	raw	1364:1366	arg1	husk					1375:1378	raw millet husk	1364:1378	raw millet husk (RMH)	1364:1384	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	4	31	theme	Dynamic	747:753	arg1	DLS					773:775	DLS	773:775	DLS	773:775	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	31	theme	Dynamic	747:753	arg1	Scattering					761:770	Dynamic Light Scattering	747:770	Dynamic Light Scattering (DLS)	747:776	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	5	32	theme	type-I	1021:1026	arg1	structure					1028:1036	a typical cellulose type-I structure	1001:1036	a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%	1001:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	4	33	theme	Solid	899:903	arg1	state					905:909	Solid state	899:909	Solid state	899:909	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	34	theme	prepared	1247:1254	arg1	CNFs					1256:1259	the prepared CNFs	1243:1259	the prepared CNFs	1243:1259	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	4	35	theme	13C	968:970	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	35	theme	13C	968:970	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	36	theme	extracted	558:566	arg1	CNFs					568:571	The extracted CNFs	554:571	The extracted CNFs	554:571	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	8	37	theme	synthetic	1471:1479	arg1	fibers					1481:1486	synthetic fibers	1471:1486	synthetic fibers	1471:1486	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	1	38	theme	millet	216:221	arg1	husk					223:226	millet husk	216:226	millet husk	216:226	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	4	39	dep	spectroscopy	625:636	arg1	DTG					848:850	DTG	848:850	DTG	848:850	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	39	dep	spectroscopy	625:636	arg1	TG					841:842	TG	841:842	TG	841:842	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	3	40	theme	acid	477:480	arg1	acid					504:507	5% oxalic acid	494:507	5% oxalic acid	494:507	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	3	40	theme	acid	477:480	arg1	hydrolysis					482:491	acid hydrolysis	477:491	acid hydrolysis (5% oxalic acid)	477:508	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	4	41	theme	Energy	779:784	arg1	Spectroscopy					803:814	Energy Dispersive X-ray Spectroscopy	779:814	Energy Dispersive X-ray Spectroscopy	779:814	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	42	theme	solid	956:960	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	42	theme	solid	956:960	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	8	43	theme	potential	1501:1509	arg1	applications					1511:1522	assorted potential applications	1492:1522	assorted potential applications	1492:1522	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	5	44	theme	index	1086:1090	arg1	diameter					1045:1052	a diameter	1043:1052	a diameter of 10-12 nm and a crystallinity index of 58.5%	1043:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	4	45	theme	X-ray	797:801	arg1	Spectroscopy					803:814	Energy Dispersive X-ray Spectroscopy	779:814	Energy Dispersive X-ray Spectroscopy	779:814	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	46	theme	specific	1124:1131	arg1	peak					1133:1136	the specific peak	1120:1136	the specific peak at 89.31 ppm	1120:1149	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	5	47	with	structure	1028:1036	arg1	diameter					1045:1052	a diameter	1043:1052	a diameter of 10-12 nm and a crystallinity index of 58.5%	1043:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	3	48	theme	%	495:495	arg1	acid					504:507	5% oxalic acid	494:507	5% oxalic acid	494:507	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	3	48	theme	%	495:495	arg1	hydrolysis					482:491	acid hydrolysis	477:491	acid hydrolysis (5% oxalic acid)	477:508	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	0	49	theme	cellulose	60:68	arg1	extraction					14:23	Chlorine-free extraction	0:23	Chlorine-free extraction	0:23	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	0	49	theme	cellulose	60:68	arg1	characterization					40:55	structural characterization	29:55	structural characterization	29:55	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	7	50	theme	maximum	1286:1292	arg1	temperature					1306:1316	a maximum degradation temperature	1284:1316	a maximum degradation temperature (Tmax)	1284:1323	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	50	theme	maximum	1286:1292	arg1	greater					1351:1357	greater	1351:1357	greater	1351:1357	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	50	theme	maximum	1286:1292	arg1	Tmax					1319:1322	Tmax	1319:1322	Tmax	1319:1322	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	8	51	theme	green	1553:1557	arg1	composites					1559:1568	manufacturing green composites	1539:1568	manufacturing green composites	1539:1568	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	1	52	theme	sustainable	191:201	arg1	worthy					252:257	an agro-waste worthy	238:257	an agro-waste worthy of consideration	238:274	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	1	52	theme	sustainable	191:201	arg1	source					203:208	a sustainable source	189:208	a sustainable source	189:208	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	6	53	theme	13C	1170:1172	arg1	NMR					1174:1176	the solid state 13C NMR	1154:1176	the solid state 13C NMR spectra	1154:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	3	54	theme	extract	540:546	arg1	CNFs					548:551	extract CNFs	540:551	extract CNFs	540:551	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	6	55	theme	solid	1158:1162	arg1	NMR					1174:1176	the solid state 13C NMR	1154:1176	the solid state 13C NMR spectra	1154:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	0	56	theme	waste	86:90	arg1	husk					92:95	waste husk	86:95	waste husk of millet (Pennisetum glaucum)	86:126	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	4	57	theme	scanning	867:874	arg1	calorimetry					876:886	Differential scanning calorimetry	854:886	Differential scanning calorimetry (DSC)	854:892	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	57	theme	scanning	867:874	arg1	DSC					889:891	DSC	889:891	DSC	889:891	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	58	theme	phase	1234:1238	arg1	existence					1200:1208	the existence	1196:1208	the existence of the type-I cellulose phase in the prepared CNFs	1196:1259	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	1	59	theme	extract	148:154	arg1	CNFs					178:181	CNFs	178:181	CNFs	178:181	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	1	59	theme	extract	148:154	arg1	nanofibers					166:175	extract cellulose nanofibers	148:175	extract cellulose nanofibers (CNFs)	148:182	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	6	60	theme	type-I	1217:1222	arg1	phase					1234:1238	the type-I cellulose phase	1213:1238	the type-I cellulose phase	1213:1238	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	5	61	theme	cellulose	1011:1019	arg1	structure					1028:1036	a typical cellulose type-I structure	1001:1036	a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%	1001:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	6	62	from	existence	1200:1208	arg1	CNFs					1256:1259	the prepared CNFs	1243:1259	the prepared CNFs	1243:1259	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	3	63	dep	subjected	464:472	arg1	followed					510:517	followed	510:517	followed by homogenization to extract CNFs	510:551	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	8	64	from	alternatives	1454:1465	arg1	composites					1559:1568	manufacturing green composites	1539:1568	manufacturing green composites	1539:1568	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	2	65	theme	components	418:427	arg1	removal					392:398	the removal	388:398	the removal of non-cellulosic components	388:427	Pre-treatments such as mercerisation, steam explosion, and peroxide bleaching (chlorine-free) were applied for the removal of non-cellulosic components.					
35217088	4	66	theme	electron	680:687	arg1	SEM					701:703	SEM	701:703	SEM	701:703	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	66	theme	electron	680:687	arg1	microscopy					689:698	Scanning electron microscopy	671:698	Scanning electron microscopy (SEM)	671:704	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	0	67	theme	structural	29:38	arg1	characterization					40:55	structural characterization	29:55	structural characterization	29:55	Chlorine-free extraction and structural characterization of cellulose nanofibers from waste husk of millet (Pennisetum glaucum).					
35217088	4	68	theme	nuclear	915:921	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	68	theme	nuclear	915:921	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	3	69	theme	husk	450:453	arg1	pulp					455:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	1	70	theme	consideration	262:274	arg1	worthy					252:257	an agro-waste worthy	238:257	an agro-waste worthy of consideration	238:274	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	1	70	theme	consideration	262:274	arg1	source					203:208	a sustainable source	189:208	a sustainable source	189:208	This study aims to extract cellulose nanofibers (CNFs) from a sustainable source, i.e. millet husk, which is an agro-waste worthy of consideration.					
35217088	7	71	theme	millet	1368:1373	arg1	RMH					1381:1383	RMH	1381:1383	RMH	1381:1383	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	71	theme	millet	1368:1373	arg1	husk					1375:1378	raw millet husk	1364:1378	raw millet husk (RMH)	1364:1384	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	3	72	theme	bleached	434:441	arg1	pulp					455:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp	430:458	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	4	73	dep	Fourier	598:604	arg1	transform					606:614	transform	606:614	transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state	606:909	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	6	74	theme	NMR	1174:1176	arg1	spectra					1178:1184	the solid state 13C NMR spectra	1154:1184	the solid state 13C NMR spectra	1154:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	4	75	theme	Light	755:759	arg1	DLS					773:775	DLS	773:775	DLS	773:775	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	75	theme	Light	755:759	arg1	Scattering					761:770	Dynamic Light Scattering	747:770	Dynamic Light Scattering (DLS)	747:776	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	2	76	theme	steam	315:319	arg1	explosion					321:329	steam explosion	315:329	steam explosion	315:329	Pre-treatments such as mercerisation, steam explosion, and peroxide bleaching (chlorine-free) were applied for the removal of non-cellulosic components.					
35217088	7	77	contain	had	1280:1282	arg1	CNFs					1275:1278	The prepared CNFs	1262:1278	The prepared CNFs	1262:1278	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	77	contain	had	1280:1282	arg2	greater					1351:1357	greater	1351:1357	greater	1351:1357	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	77	contain	had	1280:1282	arg2	Tmax					1319:1322	Tmax	1319:1322	Tmax	1319:1322	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	7	77	contain	had	1280:1282	arg2	temperature					1306:1316	a maximum degradation temperature	1284:1316	a maximum degradation temperature (Tmax)	1284:1323	The prepared CNFs had a maximum degradation temperature (Tmax) of 341 °C, that was 31 °C greater than raw millet husk (RMH).					
35217088	4	78	theme	state	962:966	arg1	NMR					972:974	solid state 13C NMR	956:974	solid state 13C NMR	956:974	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	78	theme	state	962:966	arg1	spectroscopy					942:953	nuclear magnetic resonance spectroscopy	915:953	nuclear magnetic resonance spectroscopy (solid state 13C NMR)	915:975	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	8	79	theme	study	1406:1410	arg1	outcome					1391:1397	The outcome	1387:1397	The outcome of the study	1387:1410	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	4	80	theme	Transmission	707:718	arg1	TEM					741:743	TEM	741:743	TEM	741:743	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	4	80	theme	Transmission	707:718	arg1	microscopy					729:738	Transmission electron microscopy	707:738	Transmission electron microscopy (TEM)	707:744	The extracted CNFs were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS), Energy Dispersive X-ray Spectroscopy (EDX), Thermogravimetry (TG and DTG), Differential scanning calorimetry (DSC), and Solid state 13C nuclear magnetic resonance spectroscopy (solid state 13C NMR).					
35217088	3	81	theme	5	494:494	arg1	%					495:495	%	495:495	%	495:495	The bleached millet husk pulp was subjected to acid hydrolysis (5% oxalic acid) followed by homogenization to extract CNFs.					
35217088	5	82	theme	%	1099:1099	arg1	index					1086:1090	a crystallinity index	1070:1090	a crystallinity index of 58.5%	1070:1099	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	5	82	theme	%	1099:1099	arg1	10-12 nm					1057:1064	10-12 nm	1057:1064	10-12 nm	1057:1064	The isolated CNFs show a typical cellulose type-I structure with a diameter of 10-12 nm and a crystallinity index of 58.5%.					
35217088	2	83	theme	peroxide	336:343	arg1	chlorine-free					356:368	chlorine-free	356:368	chlorine-free	356:368	Pre-treatments such as mercerisation, steam explosion, and peroxide bleaching (chlorine-free) were applied for the removal of non-cellulosic components.					
35217088	2	83	theme	peroxide	336:343	arg1	bleaching					345:353	peroxide bleaching	336:353	peroxide bleaching (chlorine-free)	336:369	Pre-treatments such as mercerisation, steam explosion, and peroxide bleaching (chlorine-free) were applied for the removal of non-cellulosic components.					
35217088	8	84	theme	assorted	1492:1499	arg1	applications					1511:1522	assorted potential applications	1492:1522	assorted potential applications	1492:1522	The outcome of the study implies that the nanofibers are prominent alternatives for synthetic fibers for assorted potential applications, especially in manufacturing green composites.					
35217088	6	85	from	89.31 ppm	1141:1149	arg1	appearance					1106:1115	The appearance	1102:1115	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra	1102:1184	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
35217088	6	85	from	89.31 ppm	1141:1149	arg1	peak					1133:1136	the specific peak	1120:1136	the specific peak at 89.31 ppm	1120:1149	The appearance of the specific peak at 89.31 ppm in the solid state 13C NMR spectra validates the existence of the type-I cellulose phase in the prepared CNFs.					
36903621	7	0	theme	ion	1230:1232	arg1	spectrometry					1239:1250	time-of-flight secondary ion mass spectrometry	1205:1250	time-of-flight secondary ion mass spectrometry (TOF-SIMS)	1205:1261	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	0	theme	ion	1230:1232	arg1	TOF-SIMS					1253:1260	TOF-SIMS	1253:1260	TOF-SIMS	1253:1260	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	8	1	theme	coating	1578:1584	arg1	organization					1586:1597	the coating organization	1574:1597	the coating organization	1574:1597	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	7	2	theme	molecular	1097:1105	arg1	distribution					1107:1118	molecular distribution	1097:1118	molecular distribution	1097:1118	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	5	3	mod	modified	862:869	arg3	substances					882:891	other substances	876:891	other substances of biological importance (DOPC, CsA and LG)	876:935	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	5	3	mod	modified	862:869	arg1	film					837:840	the Ch film	830:840	the Ch film	830:840	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	6	4	from	technique	1020:1028	arg1	support					1062:1068	the air plasma-activated PET support	1033:1068	the air plasma-activated PET support	1033:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	2	5	theme	specific	265:272	arg1	properties					274:283	specific properties	265:283	specific properties	265:283	Due to chemical inertness, PET surface modification is necessary to gain specific properties, making the polymer biocompatible.					
36903621	1	6	theme	biomedical	167:176	arg1	applications					178:189	biomedical applications	167:189	biomedical applications	167:189	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	10	7	theme	system	2050:2055	arg1	response					2057:2064	the immune system response	2039:2064	the immune system response to the presence of biomaterial	2039:2095	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	2	8	theme	biocompatible	305:317	arg1	polymer					297:303	the polymer biocompatible	293:317	the polymer biocompatible	293:317	Due to chemical inertness, PET surface modification is necessary to gain specific properties, making the polymer biocompatible.					
36903621	4	9	dep	engineering	781:791	arg1	purposes					810:817	purposes	810:817	purposes	810:817	Chitosan was employed owing to its antibacterial activity and also its ability to promote cell adhesion and proliferation favorable for tissue engineering and regeneration purposes.					
36903621	10	10	theme	biomaterial	2085:2095	arg1	presence					2073:2080	the presence	2069:2080	the presence of biomaterial	2069:2095	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	5	11	dep	importance	907:916	arg1	DOPC					919:922	DOPC	919:922	DOPC	919:922	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	5	11	dep	importance	907:916	arg1	LG					933:934	LG	933:934	LG	933:934	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	5	11	dep	importance	907:916	arg1	CsA					925:927	CsA	925:927	CsA	925:927	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	7	12	theme	surface	1344:1350	arg1	energy					1357:1362	surface free energy	1344:1362	surface free energy	1344:1362	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	9	13	from	favor	1932:1936	arg1	rid					1906:1908	rid	1906:1908	rid of the limitations in favor of increased biocompatibility	1906:1966	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	3	14	used	utilized	566:573	arg2	material					596:603	a very attractive material	578:603	a very attractive material for developing the PET coatings	578:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	14	used	utilized	566:573	arg2	films					381:385	the multi-component films	361:385	the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings	361:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	2	15	theme	surface	223:229	arg1	modification					231:242	PET surface modification	219:242	PET surface modification	219:242	Due to chemical inertness, PET surface modification is necessary to gain specific properties, making the polymer biocompatible.					
36903621	8	16	theme	polar/apolar	1705:1716	arg1	liquids					1718:1724	the polar/apolar liquids	1701:1724	the polar/apolar liquids imitating the environment of different properties	1701:1774	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	17	theme	obtained	1417:1424	arg1	results					1426:1432	The obtained results	1413:1432	The obtained results	1413:1432	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	18	from	organization	1586:1597	arg1	level					1647:1651	the molecular level	1633:1651	the molecular level	1633:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	9	19	theme	limitations	1917:1927	arg1	rid					1906:1908	rid	1906:1908	rid of the limitations in favor of increased biocompatibility	1906:1966	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	4	20	theme	antibacterial	673:685	arg1	activity					687:694	its antibacterial activity	669:694	its antibacterial activity	669:694	Chitosan was employed owing to its antibacterial activity and also its ability to promote cell adhesion and proliferation favorable for tissue engineering and regeneration purposes.					
36903621	7	21	theme	secondary	1220:1228	arg1	spectrometry					1239:1250	time-of-flight secondary ion mass spectrometry	1205:1250	time-of-flight secondary ion mass spectrometry (TOF-SIMS)	1205:1261	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	21	theme	secondary	1220:1228	arg1	TOF-SIMS					1253:1260	TOF-SIMS	1253:1260	TOF-SIMS	1253:1260	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	9	22	theme	organized	1781:1789	arg1	helpful					1818:1824	helpful	1818:1824	helpful	1818:1824	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	9	22	theme	organized	1781:1789	arg1	layers					1791:1796	The organized layers	1777:1796	The organized layers of this type	1777:1809	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	8	23	theme	different	1755:1763	arg1	properties					1765:1774	different properties	1755:1774	different properties	1755:1774	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	9	24	theme	increased	1941:1949	arg1	biocompatibility					1951:1966	increased biocompatibility	1941:1966	increased biocompatibility	1941:1966	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	1	25	theme	polymers	155:162	arg1	one					123:125	one	123:125	one	123:125	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	1	25	theme	polymers	155:162	arg1	polymers					155:162	the most frequently used polymers	130:162	the most frequently used polymers	130:162	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	8	26	theme	surface	1469:1475	arg1	properties					1477:1486	the surface properties	1465:1486	the surface properties of the films	1465:1499	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	4	27	theme	favorable	760:768	arg1	adhesion					733:740	cell adhesion	728:740	cell adhesion	728:740	Chitosan was employed owing to its antibacterial activity and also its ability to promote cell adhesion and proliferation favorable for tissue engineering and regeneration purposes.					
36903621	10	28	theme	good	1979:1982	arg1	This					1969:1972	This	1969:1972	This	1969:1972	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	10	28	theme	good	1979:1982	arg1	basis					1984:1988	a good basis	1977:1988	a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties	1977:2130	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	6	29	theme	compositions	960:971	arg1	layers					942:947	The layers	938:947	The layers of varying compositions	938:971	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	3	30	theme	paper	336:340	arg1	aim					324:326	The aim	320:326	The aim of this paper	320:340	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	4	31	theme	tissue	774:779	arg1	engineering					781:791	tissue engineering	774:791	tissue engineering	774:791	Chitosan was employed owing to its antibacterial activity and also its ability to promote cell adhesion and proliferation favorable for tissue engineering and regeneration purposes.					
36903621	7	32	theme	angle	1312:1316	arg1	measurements					1323:1334	contact angle (CA) measurements	1304:1334	contact angle (CA) measurements	1304:1334	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	8	33	theme	films	1495:1499	arg1	properties					1477:1486	the surface properties	1465:1486	the surface properties of the films	1465:1499	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	4	34	theme	cell	728:731	arg1	adhesion					733:740	cell adhesion	728:740	cell adhesion	728:740	Chitosan was employed owing to its antibacterial activity and also its ability to promote cell adhesion and proliferation favorable for tissue engineering and regeneration purposes.					
36903621	7	35	theme	atomic	1174:1179	arg1	AFM					1199:1201	AFM	1199:1201	AFM	1199:1201	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	35	theme	atomic	1174:1179	arg1	microscopy					1187:1196	atomic force microscopy	1174:1196	atomic force microscopy (AFM)	1174:1202	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	1	36	from	-PET-is	115:121	arg1	applications					178:189	biomedical applications	167:189	biomedical applications	167:189	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	1	37	theme	ethylene	92:99	arg1	Poly					87:90	Poly	87:90	Poly(ethylene terephthalate)	87:114	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	1	37	theme	ethylene	92:99	arg1	terephthalate					101:113	ethylene terephthalate	92:113	ethylene terephthalate	92:113	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	6	38	theme	air	1037:1039	arg1	support					1062:1068	the air plasma-activated PET support	1033:1068	the air plasma-activated PET support	1033:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	0	39	theme	Surface	16:22	arg1	Characterization					24:39	Surface Characterization	16:39	Surface Characterization	16:39	Preparation and Surface Characterization of Chitosan-Based Coatings for PET Materials.					
36903621	9	40	from	limitations	1917:1927	arg1	favor					1932:1936	favor	1932:1936	favor	1932:1936	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	9	41	from	rid	1906:1908	arg1	favor					1932:1936	favor	1932:1936	favor	1932:1936	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	8	42	theme	components	1523:1532	arg1	ratio					1514:1518	the molar ratio	1504:1518	the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films	1504:1673	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	0	43	theme	PET	72:74	arg1	Materials					76:84	PET Materials	72:84	PET Materials	72:84	Preparation and Surface Characterization of Chitosan-Based Coatings for PET Materials.					
36903621	0	44	theme	Coatings	59:66	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Surface Characterization of Chitosan-Based Coatings for PET Materials.					
36903621	0	44	theme	Coatings	59:66	arg1	Characterization					24:39	Surface Characterization	16:39	Surface Characterization	16:39	Preparation and Surface Characterization of Chitosan-Based Coatings for PET Materials.					
36903621	7	45	theme	X-ray	1264:1268	arg1	XPS					1298:1300	XPS	1298:1300	XPS	1298:1300	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	45	theme	X-ray	1264:1268	arg1	spectroscopy					1284:1295	X-ray photoelectron spectroscopy	1264:1295	X-ray photoelectron spectroscopy (XPS)	1264:1301	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	2	46	theme	chemical	199:206	arg1	inertness					208:216	chemical inertness	199:216	chemical inertness	199:216	Due to chemical inertness, PET surface modification is necessary to gain specific properties, making the polymer biocompatible.					
36903621	3	47	theme	cyclosporine	493:504	arg1	CsA					509:511	CsA	509:511	CsA	509:511	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	47	theme	cyclosporine	493:504	arg1	A					506:506	immunosuppressant cyclosporine A	475:506	immunosuppressant cyclosporine A (CsA)	475:512	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	8	48	theme	mechanisms	1603:1612	arg1	understanding					1557:1569	a better understanding	1548:1569	a better understanding of the coating organization and mechanisms of interactions at the molecular level	1548:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	3	49	theme	antioxidant	521:531	arg1	LG					549:550	LG	549:550	LG	549:550	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	49	theme	antioxidant	521:531	arg1	gallate					540:546	antioxidant lauryl gallate	521:546	antioxidant lauryl gallate (LG)	521:551	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	8	50	theme	interactions	1617:1628	arg1	mechanisms					1603:1612	mechanisms	1603:1612	mechanisms	1603:1612	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	50	theme	interactions	1617:1628	arg1	organization					1586:1597	the coating organization	1574:1597	the coating organization	1574:1597	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	10	51	theme	immune	2043:2048	arg1	response					2057:2064	the immune system response	2039:2064	the immune system response to the presence of biomaterial	2039:2095	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	7	52	theme	mass	1234:1237	arg1	spectrometry					1239:1250	time-of-flight secondary ion mass spectrometry	1205:1250	time-of-flight secondary ion mass spectrometry (TOF-SIMS)	1205:1261	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	52	theme	mass	1234:1237	arg1	TOF-SIMS					1253:1260	TOF-SIMS	1253:1260	TOF-SIMS	1253:1260	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	5	53	theme	biological	896:905	arg1	importance					907:916	biological importance	896:916	biological importance (DOPC, CsA and LG)	896:935	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	9	54	theme	surface	1854:1860	arg1	properties					1862:1871	the surface properties	1850:1871	the surface properties of the biomaterial	1850:1890	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	8	55	theme	organization	1586:1597	arg1	understanding					1557:1569	a better understanding	1548:1569	a better understanding of the coating organization and mechanisms of interactions at the molecular level	1548:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	10	56	theme	response	2057:2064	arg1	properties					2121:2130	its physicochemical properties	2101:2130	its physicochemical properties	2101:2130	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	10	56	theme	response	2057:2064	arg1	correlation					2024:2034	the correlation	2020:2034	the correlation of the immune system response to the presence of biomaterial	2020:2095	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	6	57	theme	varying	952:958	arg1	compositions					960:971	varying compositions	952:971	varying compositions	952:971	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	3	58	contain	containing	387:396	arg1	films					381:385	the multi-component films	361:385	the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings	361:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	Ch					408:409	Ch	408:409	Ch	408:409	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	CsA					509:511	CsA	509:511	CsA	509:511	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	DOPC					468:471	DOPC	468:471	DOPC	468:471	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	gallate					540:546	antioxidant lauryl gallate	521:546	antioxidant lauryl gallate (LG)	521:551	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg1	material					596:603	a very attractive material	578:603	a very attractive material for developing the PET coatings	578:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	LG					549:550	LG	549:550	LG	549:550	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	chitosan					398:405	chitosan	398:405	chitosan (Ch)	398:410	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	A					506:506	immunosuppressant cyclosporine A	475:506	immunosuppressant cyclosporine A (CsA)	475:512	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	58	contain	containing	387:396	arg2	1,2-dioleoyl-sn-glycero-3-phosphocholine					426:465	phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine	413:465	phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	413:472	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	9	59	theme	biomaterial	1880:1890	arg1	properties					1862:1871	the surface properties	1850:1871	the surface properties of the biomaterial	1850:1890	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	5	60	theme	Ch	834:835	arg1	film					837:840	the Ch film	830:840	the Ch film	830:840	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	5	61	theme	importance	907:916	arg1	substances					882:891	other substances	876:891	other substances of biological importance (DOPC, CsA and LG)	876:935	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	8	62	dep	allow	1538:1542	arg1	both					1653:1656	both	1653:1656	both	1653:1656	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	5	63	theme	other	876:880	arg1	substances					882:891	other substances	876:891	other substances of biological importance (DOPC, CsA and LG)	876:935	Moreover, the Ch film can be additionally modified with other substances of biological importance (DOPC, CsA and LG).					
36903621	7	64	theme	free	1352:1355	arg1	energy					1357:1362	surface free energy	1344:1362	surface free energy	1344:1362	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	8	65	dep	components	1523:1532	arg1	inside					1658:1663	inside	1658:1663	inside the films	1658:1673	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	65	dep	components	1523:1532	arg1	allow					1538:1542	allow	1538:1542	allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level	1538:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	2	66	theme	PET	219:221	arg1	modification					231:242	PET surface modification	219:242	PET surface modification	219:242	Due to chemical inertness, PET surface modification is necessary to gain specific properties, making the polymer biocompatible.					
36903621	10	67	theme	physicochemical	2105:2119	arg1	properties					2121:2130	its physicochemical properties	2101:2130	its physicochemical properties	2101:2130	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	6	68	theme	LB	1016:1017	arg1	technique					1020:1028	the Langmuir-Blodgett (LB) technique	993:1028	the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support	993:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	10	69	from	investigations	2002:2015	arg1	properties					2121:2130	its physicochemical properties	2101:2130	its physicochemical properties	2101:2130	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	10	69	from	investigations	2002:2015	arg1	correlation					2024:2034	the correlation	2020:2034	the correlation of the immune system response to the presence of biomaterial	2020:2095	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	7	70	theme	time-of-flight	1205:1218	arg1	spectrometry					1239:1250	time-of-flight secondary ion mass spectrometry	1205:1250	time-of-flight secondary ion mass spectrometry (TOF-SIMS)	1205:1261	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	70	theme	time-of-flight	1205:1218	arg1	TOF-SIMS					1253:1260	TOF-SIMS	1253:1260	TOF-SIMS	1253:1260	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	71	dep	energy	1357:1362	arg1	the					1340:1342	the	1340:1342	the	1340:1342	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	6	72	theme	Langmuir-Blodgett	997:1013	arg1	technique					1020:1028	the Langmuir-Blodgett (LB) technique	993:1028	the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support	993:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	1	73	theme	used	150:153	arg1	polymers					155:162	the most frequently used polymers	130:162	the most frequently used polymers	130:162	Poly(ethylene terephthalate)-PET-is one of the most frequently used polymers in biomedical applications.					
36903621	8	74	theme	properties	1477:1486	arg1	dependence					1451:1460	the dependence	1447:1460	the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties	1447:1774	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	75	from	dependence	1451:1460	arg1	ratio					1514:1518	the molar ratio	1504:1518	the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films	1504:1673	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	76	theme	properties	1765:1774	arg1	environment					1740:1750	the environment	1736:1750	the environment of different properties	1736:1774	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	7	77	theme	force	1181:1185	arg1	AFM					1199:1201	AFM	1199:1201	AFM	1199:1201	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	77	theme	force	1181:1185	arg1	microscopy					1187:1196	atomic force microscopy	1174:1196	atomic force microscopy (AFM)	1174:1202	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	78	theme	contact	1304:1310	arg1	CA					1319:1320	CA	1319:1320	CA	1319:1320	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	78	theme	contact	1304:1310	arg1	angle					1312:1316	contact angle	1304:1316	contact angle (CA) measurements	1304:1334	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	8	79	from	mechanisms	1603:1612	arg1	level					1647:1651	the molecular level	1633:1651	the molecular level	1633:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	6	80	theme	plasma-activated	1041:1056	arg1	support					1062:1068	the air plasma-activated PET support	1033:1068	the air plasma-activated PET support	1033:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	8	81	theme	molar	1508:1512	arg1	ratio					1514:1518	the molar ratio	1504:1518	the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films	1504:1673	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	82	from	level	1647:1651	arg1	interactions					1617:1628	interactions	1617:1628	interactions at the molecular level	1617:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	82	from	level	1647:1651	arg1	mechanisms					1603:1612	mechanisms	1603:1612	mechanisms	1603:1612	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	8	82	from	level	1647:1651	arg1	organization					1586:1597	the coating organization	1574:1597	the coating organization	1574:1597	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	3	83	theme	phospholipid	413:424	arg1	1,2-dioleoyl-sn-glycero-3-phosphocholine					426:465	phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine	413:465	phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	413:472	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	83	theme	phospholipid	413:424	arg1	DOPC					468:471	DOPC	468:471	DOPC	468:471	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	84	theme	multi-component	365:379	arg1	films					381:385	the multi-component films	361:385	the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings	361:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	84	theme	multi-component	365:379	arg1	material					596:603	a very attractive material	578:603	a very attractive material for developing the PET coatings	578:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	85	theme	immunosuppressant	475:491	arg1	CsA					509:511	CsA	509:511	CsA	509:511	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	85	theme	immunosuppressant	475:491	arg1	A					506:506	immunosuppressant cyclosporine A	475:506	immunosuppressant cyclosporine A (CsA)	475:512	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	0	86	theme	Chitosan-Based	44:57	arg1	Coatings					59:66	Chitosan-Based Coatings	44:66	Chitosan-Based Coatings	44:66	Preparation and Surface Characterization of Chitosan-Based Coatings for PET Materials.					
36903621	10	87	theme	further	1994:2000	arg1	investigations					2002:2015	further investigations	1994:2015	further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties	1994:2130	This is a good basis for further investigations on the correlation of the immune system response to the presence of biomaterial and its physicochemical properties.					
36903621	7	88	theme	photoelectron	1270:1282	arg1	XPS					1298:1300	XPS	1298:1300	XPS	1298:1300	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	7	88	theme	photoelectron	1270:1282	arg1	spectroscopy					1284:1295	X-ray photoelectron spectroscopy	1264:1295	X-ray photoelectron spectroscopy (XPS)	1264:1301	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	3	89	theme	PET	624:626	arg1	coatings					628:635	the PET coatings	620:635	the PET coatings	620:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	7	90	theme	surface	1121:1127	arg1	chemistry					1129:1137	surface chemistry	1121:1137	surface chemistry	1121:1137	Then their nanostructure, molecular distribution, surface chemistry and wettability were determined by atomic force microscopy (AFM), time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray photoelectron spectroscopy (XPS), contact angle (CA) measurements and the surface free energy and its components' determination, respectively.					
36903621	9	91	theme	type	1806:1809	arg1	helpful					1818:1824	helpful	1818:1824	helpful	1818:1824	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	9	91	theme	type	1806:1809	arg1	layers					1791:1796	The organized layers	1777:1796	The organized layers of this type	1777:1809	The organized layers of this type can be helpful in gaining control over the surface properties of the biomaterial, thus getting rid of the limitations in favor of increased biocompatibility.					
36903621	3	92	theme	attractive	585:594	arg1	films					381:385	the multi-component films	361:385	the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings	361:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	92	theme	attractive	585:594	arg1	material					596:603	a very attractive material	578:603	a very attractive material for developing the PET coatings	578:635	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	8	93	theme	better	1550:1555	arg1	understanding					1557:1569	a better understanding	1548:1569	a better understanding of the coating organization and mechanisms of interactions at the molecular level	1548:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36903621	6	94	theme	PET	1058:1060	arg1	support					1062:1068	the air plasma-activated PET support	1033:1068	the air plasma-activated PET support	1033:1068	The layers of varying compositions were prepared using the Langmuir-Blodgett (LB) technique on the air plasma-activated PET support.					
36903621	3	95	theme	lauryl	533:538	arg1	LG					549:550	LG	549:550	LG	549:550	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	3	95	theme	lauryl	533:538	arg1	gallate					540:546	antioxidant lauryl gallate	521:546	antioxidant lauryl gallate (LG)	521:551	The aim of this paper is to characterize the multi-component films containing chitosan (Ch), phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), immunosuppressant cyclosporine A (CsA) and/or antioxidant lauryl gallate (LG) which can be utilized as a very attractive material for developing the PET coatings.					
36903621	8	96	theme	molecular	1637:1645	arg1	level					1647:1651	the molecular level	1633:1651	the molecular level	1633:1651	The obtained results show clearly the dependence of the surface properties of the films on the molar ratio of components and allow for a better understanding of the coating organization and mechanisms of interactions at the molecular level both inside the films and between the films and the polar/apolar liquids imitating the environment of different properties.					
36948340	6	0	theme	enzyme	1352:1357	arg1	amount					1335:1340	the amount	1331:1340	the amount of active enzyme	1331:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	0	theme	enzyme	1352:1357	arg1	enzyme					1352:1357	active enzyme	1345:1357	active enzyme	1345:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	0	theme	enzyme	1352:1357	arg1	amount					1303:1308	the amount	1299:1308	the amount of loaded lactate	1299:1326	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	0	theme	enzyme	1352:1357	arg1	lactate					1320:1326	loaded lactate	1313:1326	loaded lactate	1313:1326	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	1	theme	release	1271:1277	arg1	modulation					1253:1262	the modulation	1249:1262	the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme	1249:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	1	2	theme	lactate	269:275	arg1	release					258:264	release	258:264	release of lactate	258:275	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	0	3	theme	electrospun	94:104	arg1	fibers					106:111	proteinase K/polymer electrospun fibers	73:111	proteinase K/polymer electrospun fibers	73:111	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	2	4	theme	acid	372:375	arg1	protease					514:521	a protease	512:521	a protease that catalyzes the degradation of polylactic acid into lactate	512:584	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	4	theme	acid	372:375	arg1	mixture					350:356	a mixture	348:356	a mixture	348:356	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	3	5	theme	enzymatic	672:680	arg1	activity					682:689	its enzymatic activity	668:689	its enzymatic activity	668:689	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	2	6	theme	acid	568:571	arg1	degradation					542:552	the degradation	538:552	the degradation of polylactic acid into lactate	538:584	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	5	7	theme	lactate-loaded	893:906	arg1	hydrogel					908:915	the lactate-loaded hydrogel	889:915	the lactate-loaded hydrogel	889:915	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	3	8	theme	electrospinning	706:720	arg1	process					722:728	the electrospinning process	702:728	the electrospinning process	702:728	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	2	9	theme	polylactic	557:566	arg1	acid					568:571	polylactic acid	557:571	polylactic acid into lactate	557:584	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	10	theme	lactate	303:309	arg1	release					292:298	The prolonged release	278:298	The prolonged release of lactate	278:309	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	5	11	theme	K	952:952	arg1	fibers					954:959	the polylactic acid/proteinase K fibers	921:959	the polylactic acid/proteinase K fibers	921:959	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	5	12	theme	enzymatic	1113:1121	arg1	activity					1123:1130	the enzymatic activity	1109:1130	the enzymatic activity	1109:1130	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	4	13	theme	alginate	838:845	arg1	hydrogel					847:854	the lactate-loaded alginate hydrogel	819:854	the lactate-loaded alginate hydrogel	819:854	Besides, burst release is obtained from the lactate-loaded alginate hydrogel.					
36948340	5	14	dep	low-pressure	992:1003	arg1	0.3 mbar					1006:1013	0.3 mbar	1006:1013	0.3 mbar	1006:1013	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	2	15	dep	K	392:392	arg1	0.99 g					423:428	0.99 g	423:428	0.99 g	423:428	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	15	dep	K	392:392	arg1	26.0 mg					395:401	26.0 mg	395:401	26.0 mg of proteinase K	395:417	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	5	16	from	300 W	1018:1022	arg1	0.3 mbar					1006:1013	0.3 mbar	1006:1013	0.3 mbar	1006:1013	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	2	17	theme	proteinase	406:415	arg1	K					417:417	proteinase K	406:417	proteinase K	406:417	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	4	18	theme	lactate-loaded	823:836	arg1	hydrogel					847:854	the lactate-loaded alginate hydrogel	819:854	the lactate-loaded alginate hydrogel	819:854	Besides, burst release is obtained from the lactate-loaded alginate hydrogel.					
36948340	5	19	theme	low-pressure	992:1003	arg1	treatment					1039:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	5	20	theme	successful	861:870	arg1	assembly					872:879	The successful assembly	857:879	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers	857:959	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	0	21	theme	lactate	20:26	arg1	release					28:34	Immediate-sustained lactate release	0:34	Immediate-sustained lactate release using alginate hydrogel	0:58	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	6	22	theme	active	1345:1350	arg1	enzyme					1352:1357	active enzyme	1345:1357	active enzyme	1345:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	2	23	theme	optimal	488:494	arg1	case					496:499	the optimal case	484:499	the optimal case	484:499	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	6	24	theme	fast	1181:1184	arg1	release					1229:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	25	dep	fast	1181:1184	arg1	<					1187:1187	< 24 h	1187:1192	< 24 h	1187:1192	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	0	26	theme	Immediate-sustained	0:18	arg1	release					28:34	Immediate-sustained lactate release	0:34	Immediate-sustained lactate release using alginate hydrogel	0:58	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	5	27	theme	hydrophobic	1067:1077	arg1	fibers					1079:1084	hydrophobic fibers	1067:1084	hydrophobic fibers	1067:1084	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	3	28	theme	mild	745:748	arg1	conditions					762:771	the mild operational conditions	741:771	the mild operational conditions used	741:776	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	6	29	theme	lactate	1320:1326	arg1	amount					1335:1340	the amount	1331:1340	the amount of active enzyme	1331:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	29	theme	lactate	1320:1326	arg1	enzyme					1352:1357	active enzyme	1345:1357	active enzyme	1345:1357	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	29	theme	lactate	1320:1326	arg1	amount					1303:1308	the amount	1299:1308	the amount of loaded lactate	1299:1326	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	29	theme	lactate	1320:1326	arg1	lactate					1320:1326	loaded lactate	1313:1326	loaded lactate	1313:1326	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	1	30	theme	single	219:224	arg1	system					226:231	a single system	217:231	a single system	217:231	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	2	31	theme	PLA	433:435	arg1	0.99 g					423:428	0.99 g	423:428	0.99 g	423:428	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	31	theme	PLA	433:435	arg1	26.0 mg					395:401	26.0 mg	395:401	26.0 mg of proteinase K	395:417	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	6	32	theme	loaded	1313:1318	arg1	lactate					1320:1326	loaded lactate	1313:1326	loaded lactate	1313:1326	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	1	33	theme	able	196:199	arg1	vehicle					188:194	delivery vehicle	179:194	delivery vehicle able to combine into a single system both burst	179:242	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	5	34	theme	polylactic	925:934	arg1	fibers					954:959	the polylactic acid/proteinase K fibers	921:959	the polylactic acid/proteinase K fibers	921:959	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	2	35	from	acetone	473:479	arg1	case					496:499	the optimal case	484:499	the optimal case	484:499	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	36	theme	chloroform	462:471	arg1	6 mL					450:453	6 mL	450:453	6 mL of 2:1 chloroform	450:471	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	0	37	theme	alginate	42:49	arg1	hydrogel					51:58	alginate hydrogel	42:58	alginate hydrogel	42:58	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	3	38	theme	microfibers	606:616	arg1	degradation					591:601	The degradation	587:601	The degradation of microfibers into lactate	587:629	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	5	39	theme	oxygen	1025:1030	arg1	treatment					1039:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	2	40	theme	K	417:417	arg1	0.99 g					423:428	0.99 g	423:428	0.99 g	423:428	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	40	theme	K	417:417	arg1	26.0 mg					395:401	26.0 mg	395:401	26.0 mg of proteinase K	395:417	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	41	theme	2:1	458:460	arg1	chloroform					462:471	2:1 chloroform	458:471	2:1 chloroform	458:471	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	5	42	theme	plasma	1032:1037	arg1	treatment					1039:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment	990:1047	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	2	43	theme	polylactic	361:370	arg1	acid					372:375	polylactic acid	361:375	polylactic acid	361:375	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	3	44	theme	operational	750:760	arg1	conditions					762:771	the mild operational conditions	741:771	the mild operational conditions used	741:776	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	1	45	theme	microfibers-hydrogel	135:154	arg1	composite					166:174	a microfibers-hydrogel assembled composite	133:174	a microfibers-hydrogel assembled composite	133:174	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	4	46	theme	burst	788:792	arg1	release					794:800	burst release	788:800	burst release	788:800	Besides, burst release is obtained from the lactate-loaded alginate hydrogel.					
36948340	2	47	dep	26.0 mg	395:401	arg1	acetone					473:479	acetone	473:479	26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case	395:499	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	48	theme	prolonged	282:290	arg1	release					292:298	The prolonged release	278:298	The prolonged release of lactate	278:309	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	6	49	theme	lactate	1221:1227	arg1	release					1229:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	1	50	theme	assembled	156:164	arg1	composite					166:174	a microfibers-hydrogel assembled composite	133:174	a microfibers-hydrogel assembled composite	133:174	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	6	51	theme	>	1210:1210	arg1	10 days					1212:1218	> 10 days	1210:1218	> 10 days	1210:1218	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	1	52	theme	delivery	179:186	arg1	vehicle					188:194	delivery vehicle	179:194	delivery vehicle able to combine into a single system both burst	179:242	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	5	53	theme	acid/proteinase	936:950	arg1	fibers					954:959	the polylactic acid/proteinase K fibers	921:959	the polylactic acid/proteinase K fibers	921:959	The successful assembly between the lactate-loaded hydrogel and the polylactic acid/proteinase K fibers has been favored by applying a low-pressure (0.3 mbar at 300 W) oxygen plasma treatment, which transforms hydrophobic fibers into hydrophilic while the enzymatic activity is still maintained.					
36948340	0	54	theme	K/polymer	84:92	arg1	fibers					106:111	proteinase K/polymer electrospun fibers	73:111	proteinase K/polymer electrospun fibers	73:111	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	3	55	theme	proteinase	645:654	arg1	K					656:656	proteinase K	645:656	proteinase K	645:656	The degradation of microfibers into lactate reflects that proteinase K preserves its enzymatic activity even after the electrospinning process because of the mild operational conditions used.					
36948340	6	56	theme	sustained	1199:1207	arg1	release					1229:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	both fast (< 24 h) and sustained (> 10 days) lactate release	1176:1235	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	6	57	dep	sustained	1199:1207	arg1	10 days					1212:1218	> 10 days	1210:1218	> 10 days	1210:1218	The composite displays both fast (< 24 h) and sustained (> 10 days) lactate release, and allows the modulation of the release by adjusting either the amount of loaded lactate or the amount of active enzyme.					
36948340	2	58	theme	K	392:392	arg1	protease					514:521	a protease	512:521	a protease that catalyzes the degradation of polylactic acid into lactate	512:584	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	2	58	theme	K	392:392	arg1	mixture					350:356	a mixture	348:356	a mixture	348:356	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
36948340	0	59	theme	proteinase	73:82	arg1	fibers					106:111	proteinase K/polymer electrospun fibers	73:111	proteinase K/polymer electrospun fibers	73:111	Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.					
36948340	1	60	dep	system	226:231	arg1	both					233:236	both	233:236	both	233:236	This work proposes a microfibers-hydrogel assembled composite as delivery vehicle able to combine into a single system both burst and prolonged release of lactate.					
36948340	2	61	theme	proteinase	381:390	arg1	K					392:392	proteinase K	381:392	proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case)	381:500	The prolonged release of lactate has been achieved by electrospinning a mixture of polylactic acid and proteinase K (26.0 mg of proteinase K and 0.99 g of PLA dissolved in 6 mL of 2:1 chloroform:acetone in the optimal case), which is a protease that catalyzes the degradation of polylactic acid into lactate.					
35708325	14	0	theme	REE	2701:2703	arg1	resources					2705:2713	REE resources	2701:2713	REE resources	2701:2713	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	4	1	from	deposit	659:665	arg1	China					683:687	Southeastern China	670:687	Southeastern China	670:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	4	2	theme	community	552:560	arg1	composition					562:572	the microbial community composition	538:572	the microbial community composition	538:572	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	9	3	theme	crucial	1528:1534	arg1	contribution					1536:1547	the crucial contribution	1524:1547	the crucial contribution of fungi and bacteria in the supergene REE mineralization	1524:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	1	4	theme	earth	122:126	arg1	REEs					162:165	heavy REEs	156:165	especially heavy REEs (HREEs)	145:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	4	theme	earth	122:126	arg1	REEs					138:141	REEs	138:141	REEs	138:141	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	4	theme	earth	122:126	arg1	elements					128:135	rare earth elements	117:135	rare earth elements (REEs)	117:142	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	9	5	theme	efficient	1638:1646	arg1	utilization					1648:1658	efficient utilization	1638:1658	efficient utilization of mineral resources	1638:1679	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	10	6	theme	such	1918:1921	arg1	deposits					1923:1930	such deposits	1918:1930	such deposits	1918:1930	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	3	7	theme	demand	498:503	arg1	%					481:481	over 90%	474:481	over 90% of global HREE demand	474:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	3	7	theme	demand	498:503	arg1	demand					498:503	global HREE demand	486:503	global HREE demand	486:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	7	8	theme	HREEs	1366:1370	arg1	enrichment					1352:1361	an enrichment	1349:1361	an enrichment of HREEs in the deposit	1349:1385	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	4	9	theme	regolith-hosted	639:653	arg1	deposit					659:665	a regolith-hosted REE deposit	637:665	a regolith-hosted REE deposit in Southeastern China	637:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	11	10	theme	community	2039:2047	arg1	composition					2049:2059	the microbial community composition	2025:2059	the microbial community composition	2025:2059	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	13	11	theme	phosphate	2379:2387	arg1	carboxyl					2366:2373	the surface carboxyl and phosphate groups	2354:2394	carboxyl	2366:2373	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	11	theme	phosphate	2379:2387	arg1	groups					2389:2394	the surface carboxyl and phosphate groups	2354:2394	groups	2389:2394	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	11	theme	phosphate	2379:2387	arg1	sites					2407:2411	active sites	2400:2411	active sites for REE adsorption	2400:2430	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	9	12	theme	resources	1671:1679	arg1	utilization					1648:1658	efficient utilization	1638:1658	efficient utilization of mineral resources	1638:1679	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	7	13	from	acids	1269:1273	arg1	wall					1287:1290	the cell wall	1278:1290	the cell wall	1278:1290	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	4	14	theme	complete	596:603	arg1	profile					616:622	a complete weathering profile	594:622	a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China	594:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	13	15	theme	teichoic	2439:2446	arg1	acids					2448:2452	teichoic acids	2439:2452	teichoic acids in the cell walls of G+ bacteria	2439:2485	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	2	16	theme	supergene	276:284	arg1	environments					286:297	supergene environments	276:297	supergene environments	276:297	It is generally accepted that microorganisms are able to dissolve minerals and mobilize elements in supergene environments.					
35708325	8	17	theme	present	1392:1398	arg1	study					1400:1404	The present study	1388:1404	The present study	1388:1404	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	10	18	from	role	1736:1739	arg1	formation					1766:1774	the formation	1762:1774	the formation of regolith-hosted rare earth element (REE) deposits	1762:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	3	19	from	roles	335:339	arg1	formation					366:374	the formation	362:374	the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	362:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	10	20	theme	earth	1800:1804	arg1	REE					1815:1817	REE	1815:1817	REE	1815:1817	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	10	20	theme	earth	1800:1804	arg1	element					1806:1812	rare earth element	1795:1812	regolith-hosted rare earth element (REE) deposits	1779:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	10	21	with	regions	1964:1970	arg1	activities					1994:2003	strong microbial activities	1977:2003	strong microbial activities	1977:2003	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	10	22	theme	strong	1977:1982	arg1	activities					1994:2003	strong microbial activities	1977:2003	strong microbial activities	1977:2003	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	13	23	theme	bacteria	2478:2485	arg1	walls					2466:2470	the cell walls	2457:2470	the cell walls of G+ bacteria	2457:2485	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	10	24	theme	regolith-hosted	1779:1793	arg1	deposits					1820:1827	regolith-hosted rare earth element (REE) deposits	1779:1827	regolith-hosted rare earth element (REE) deposits	1779:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	1	25	theme	elements	128:135	arg1	source					107:112	an important source	94:112	an important source of rare earth elements (REEs), especially heavy REEs (HREEs)	94:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	25	theme	elements	128:135	arg1	deposits					81:88	Exogenic deposits	72:88	Exogenic deposits	72:88	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	7	26	from	enrichment	1352:1361	arg1	deposit					1379:1385	the deposit	1375:1385	the deposit	1375:1385	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	8	27	theme	first	1419:1423	arg1	database					1425:1432	the first database	1415:1432	the first database of microbial community in regolith-hosted REE deposits	1415:1487	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	7	28	theme	HREE	1321:1324	arg1	adsorption					1326:1335	HREE adsorption	1321:1335	HREE adsorption	1321:1335	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	7	29	from	HREEs	1366:1370	arg1	deposit					1379:1385	the deposit	1375:1385	the deposit	1375:1385	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	14	30	theme	REE	2623:2625	arg1	deposits					2627:2634	supergene REE deposits	2613:2634	supergene REE deposits	2613:2634	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	8	31	theme	community	1447:1455	arg1	database					1425:1432	the first database	1415:1432	the first database of microbial community in regolith-hosted REE deposits	1415:1487	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	4	32	theme	Southeastern	670:681	arg1	China					683:687	Southeastern China	670:687	Southeastern China	670:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	11	33	from	composition	2049:2059	arg1	kind					2112:2115	this kind	2107:2115	this kind of deposit	2107:2126	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	5	34	from	variations	865:874	arg1	contents					883:890	REE contents	879:890	REE contents	879:890	Our results provide evidence that the variations in REE contents are correlated with microbial community along the profile.					
35708325	1	35	theme	heavy	156:160	arg1	HREEs					168:172	HREEs	168:172	HREEs	168:172	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	35	theme	heavy	156:160	arg1	REEs					162:165	heavy REEs	156:165	especially heavy REEs (HREEs)	145:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	35	theme	heavy	156:160	arg1	elements					128:135	rare earth elements	117:135	rare earth elements (REEs)	117:142	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	8	36	theme	regolith-hosted	1460:1474	arg1	deposits					1480:1487	regolith-hosted REE deposits	1460:1487	regolith-hosted REE deposits	1460:1487	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	12	37	theme	functional	2250:2259	arg1	microorganisms					2261:2274	the functional microorganisms	2246:2274	the functional microorganisms contributing to REE enrichment and fractionation	2246:2323	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	1	38	theme	rare	117:120	arg1	REEs					162:165	heavy REEs	156:165	especially heavy REEs (HREEs)	145:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	38	theme	rare	117:120	arg1	REEs					138:141	REEs	138:141	REEs	138:141	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	38	theme	rare	117:120	arg1	elements					128:135	rare earth elements	117:135	rare earth elements (REEs)	117:142	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	13	39	theme	cell	2461:2464	arg1	walls					2466:2470	the cell walls	2457:2470	the cell walls of G+ bacteria	2457:2485	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	14	40	theme	microorganisms	2578:2591	arg1	importance					2564:2573	the importance	2560:2573	the importance of microorganisms in the formation of supergene REE deposits	2560:2634	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	3	41	theme	REE	421:423	arg1	deposits					425:432	regolith-hosted REE deposits	405:432	regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	405:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	7	42	theme	main	1306:1309	arg1	sites					1311:1315	the main sites	1302:1315	the main sites for HREE adsorption	1302:1335	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	7	42	theme	main	1306:1309	arg1	acids					1269:1273	teichoic acids	1260:1273	teichoic acids in the cell wall	1260:1290	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	12	43	theme	spectroscopic	2214:2226	arg1	characterization					2228:2243	spectroscopic characterization	2214:2243	spectroscopic characterization	2214:2243	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	5	44	theme	microbial	912:920	arg1	community					922:930	microbial community	912:930	microbial community along the profile	912:948	Our results provide evidence that the variations in REE contents are correlated with microbial community along the profile.					
35708325	3	45	theme	microorganisms	344:357	arg1	roles					335:339	the roles	331:339	the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	331:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	4	46	theme	microorganisms	730:743	arg1	contributions					713:725	the striking contributions	700:725	the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs)	700:824	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	0	47	theme	REE	26:28	arg1	Mineralization					30:43	REE Mineralization	26:43	REE Mineralization	26:43	Microorganisms Accelerate REE Mineralization in Supergene Environments.					
35708325	12	48	dep	REE	2292:2294	arg1	enrichment					2296:2305	enrichment	2296:2305	enrichment	2296:2305	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	9	49	theme	fungi	1552:1556	arg1	contribution					1536:1547	the crucial contribution	1524:1547	the crucial contribution of fungi and bacteria in the supergene REE mineralization	1524:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	3	50	theme	deposits	388:395	arg1	formation					366:374	the formation	362:374	the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	362:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	7	51	dep	Bacillus	1200:1207	arg1	HREEs					1249:1253	preferentially adsorbed HREEs	1225:1253	preferentially adsorbed HREEs	1225:1253	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	12	52	theme	adsorption	2186:2195	arg1	experiments					2197:2207	batch adsorption experiments	2180:2207	batch adsorption experiments	2180:2207	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	2	53	from	elements	264:271	arg1	environments					286:297	supergene environments	276:297	supergene environments	276:297	It is generally accepted that microorganisms are able to dissolve minerals and mobilize elements in supergene environments.					
35708325	7	54	theme	bacteria	1117:1124	arg1	strains					1126:1132	bacteria strains	1117:1132	bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs	1117:1253	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	9	55	theme	bacteria	1562:1569	arg1	contribution					1536:1547	the crucial contribution	1524:1547	the crucial contribution of fungi and bacteria in the supergene REE mineralization	1524:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	6	56	theme	REEs	1010:1013	arg1	accumulation					994:1005	the accumulation	990:1005	the accumulation of REEs	990:1013	Both fungi and bacteria contributed to the accumulation of REEs, whereas bacteria played a key role in the fractionation between HREEs and LREEs.					
35708325	12	57	theme	high-throughput	2152:2166	arg1	sequencing					2168:2177	high-throughput sequencing	2152:2177	high-throughput sequencing	2152:2177	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	9	58	theme	REE	1588:1590	arg1	mineralization					1592:1605	the supergene REE mineralization	1574:1605	the supergene REE mineralization	1574:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	14	59	theme	resources	2705:2713	arg1	bioutilization					2683:2696	the bioutilization	2679:2696	the bioutilization of REE resources	2679:2713	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	11	60	theme	deposit	2120:2126	arg1	kind					2112:2115	this kind	2107:2115	this kind of deposit	2107:2126	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	10	61	theme	deposit	1885:1891	arg1	exploitation					1893:1904	deposit exploitation	1885:1904	deposit exploitation	1885:1904	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	10	62	theme	microorganisms	1744:1757	arg1	role					1736:1739	the role	1732:1739	the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits	1732:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	4	63	theme	microbial	542:550	arg1	composition					562:572	the microbial community composition	538:572	the microbial community composition	538:572	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	3	64	theme	HREE	493:496	arg1	demand					498:503	global HREE demand	486:503	global HREE demand	486:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	13	65	theme	surface	2358:2364	arg1	carboxyl					2366:2373	the surface carboxyl and phosphate groups	2354:2394	carboxyl	2366:2373	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	65	theme	surface	2358:2364	arg1	groups					2389:2394	the surface carboxyl and phosphate groups	2354:2394	groups	2389:2394	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	65	theme	surface	2358:2364	arg1	sites					2407:2411	active sites	2400:2411	active sites for REE adsorption	2400:2430	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	11	66	theme	microbial	2029:2037	arg1	composition					2049:2059	the microbial community composition	2025:2059	the microbial community composition	2025:2059	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	9	67	theme	mineral	1663:1669	arg1	resources					1671:1679	mineral resources	1663:1679	mineral resources	1663:1679	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	10	68	theme	subtropical	1952:1962	arg1	regions					1964:1970	subtropical regions	1952:1970	subtropical regions with strong microbial activities	1952:2003	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	13	69	theme	REE	2495:2497	arg1	fractionation					2499:2511	REE fractionation	2495:2511	REE fractionation	2495:2511	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	12	70	theme	experiments	2197:2207	arg1	combination					2137:2147	a combination	2135:2147	a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization	2135:2243	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	10	71	theme	element	1806:1812	arg1	deposits					1820:1827	regolith-hosted rare earth element (REE) deposits	1779:1827	regolith-hosted rare earth element (REE) deposits	1779:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	14	72	theme	experimental	2653:2664	arg1	evidence					2666:2673	experimental evidence	2653:2673	experimental evidence for the bioutilization of REE resources	2653:2713	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	9	73	theme	biological	1687:1696	arg1	pathway					1698:1704	a biological pathway	1685:1704	a biological pathway	1685:1704	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	4	74	theme	weathering	605:614	arg1	profile					616:622	a complete weathering profile	594:622	a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China	594:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	10	75	theme	microbial	1984:1992	arg1	activities					1994:2003	strong microbial activities	1977:2003	strong microbial activities	1977:2003	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	13	76	theme	G+	2475:2476	arg1	bacteria					2478:2485	G+ bacteria	2475:2485	G+ bacteria	2475:2485	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	10	77	theme	rare	1795:1798	arg1	REE					1815:1817	REE	1815:1817	REE	1815:1817	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	10	77	theme	rare	1795:1798	arg1	element					1806:1812	rare earth element	1795:1812	regolith-hosted rare earth element (REE) deposits	1779:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	5	78	theme	REE	879:881	arg1	contents					883:890	REE contents	879:890	REE contents	879:890	Our results provide evidence that the variations in REE contents are correlated with microbial community along the profile.					
35708325	13	79	from	acids	2448:2452	arg1	walls					2466:2470	the cell walls	2457:2470	the cell walls of G+ bacteria	2457:2485	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	10	80	theme	deposits	1820:1827	arg1	formation					1766:1774	the formation	1762:1774	the formation of regolith-hosted rare earth element (REE) deposits	1762:1827	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	14	81	theme	deposits	2627:2634	arg1	formation					2600:2608	the formation	2596:2608	the formation of supergene REE deposits	2596:2634	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	11	82	theme	REE	2085:2087	arg1	mineralization					2089:2102	REE mineralization	2085:2102	REE mineralization	2085:2102	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	8	83	theme	microbial	1437:1445	arg1	community					1447:1455	microbial community	1437:1455	microbial community	1437:1455	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	9	84	from	contribution	1536:1547	arg1	mineralization					1592:1605	the supergene REE mineralization	1574:1605	the supergene REE mineralization	1574:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	14	85	theme	supergene	2613:2621	arg1	deposits					2627:2634	supergene REE deposits	2613:2634	supergene REE deposits	2613:2634	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	4	86	theme	REE	655:657	arg1	deposit					659:665	a regolith-hosted REE deposit	637:665	a regolith-hosted REE deposit in Southeastern China	637:687	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	7	87	from	deposit	1379:1385	arg1	enrichment					1352:1361	an enrichment	1349:1361	an enrichment of HREEs in the deposit	1349:1385	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	8	88	theme	REE	1476:1478	arg1	deposits					1480:1487	regolith-hosted REE deposits	1460:1487	regolith-hosted REE deposits	1460:1487	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	7	89	theme	Gram-positive	1161:1173	arg1	bacteria					1175:1182	the profile, Gram-positive bacteria	1148:1182	bacteria	1175:1182	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	1	90	theme	Exogenic	72:79	arg1	source					107:112	an important source	94:112	an important source of rare earth elements (REEs), especially heavy REEs (HREEs)	94:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	90	theme	Exogenic	72:79	arg1	deposits					81:88	Exogenic deposits	72:88	Exogenic deposits	72:88	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	11	91	from	contribution	2069:2080	arg1	kind					2112:2115	this kind	2107:2115	this kind of deposit	2107:2126	Little is known of the microbial community composition and its contribution to REE mineralization in this kind of deposit.					
35708325	7	92	theme	profile	1152:1158	arg1	bacteria					1175:1182	the profile, Gram-positive bacteria	1148:1182	bacteria	1175:1182	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	10	93	dep	IMPORTANCE	1707:1716	arg1	Understanding					1718:1730	Understanding	1718:1730	Understanding	1718:1730	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	8	94	from	database	1425:1432	arg1	deposits					1480:1487	regolith-hosted REE deposits	1460:1487	regolith-hosted REE deposits	1460:1487	The present study provides the first database of microbial community in regolith-hosted REE deposits.					
35708325	1	95	theme	important	97:105	arg1	source					107:112	an important source	94:112	an important source of rare earth elements (REEs), especially heavy REEs (HREEs)	94:173	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	1	95	theme	important	97:105	arg1	deposits					81:88	Exogenic deposits	72:88	Exogenic deposits	72:88	Exogenic deposits are an important source of rare earth elements (REEs), especially heavy REEs (HREEs).					
35708325	7	96	attach	isolated	1134:1141	arg1	bacteria					1175:1182	the profile, Gram-positive bacteria	1148:1182	bacteria	1175:1182	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	7	96	attach	isolated	1134:1141	arg2	strains					1126:1132	bacteria strains	1117:1132	bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs	1117:1253	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	4	97	theme	striking	704:711	arg1	contributions					713:725	the striking contributions	700:725	the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs)	700:824	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	3	98	theme	regolith-hosted	405:419	arg1	deposits					425:432	regolith-hosted REE deposits	405:432	regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	405:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	7	99	theme	strains	1126:1132	arg1	advantage					1104:1112	advantage	1104:1112	advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs	1104:1253	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	7	100	theme	cell	1282:1285	arg1	wall					1287:1290	the cell wall	1278:1290	the cell wall	1278:1290	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	12	101	theme	characterization	2228:2243	arg1	combination					2137:2147	a combination	2135:2147	a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization	2135:2243	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	3	102	theme	HREE	446:449	arg1	enrichment					451:460	HREE enrichment	446:460	HREE enrichment	446:460	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	0	103	theme	Supergene	48:56	arg1	Environments					58:69	Supergene Environments	48:69	Supergene Environments	48:69	Microorganisms Accelerate REE Mineralization in Supergene Environments.					
35708325	14	104	from	importance	2564:2573	arg1	formation					2600:2608	the formation	2596:2608	the formation of supergene REE deposits	2596:2634	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	12	105	theme	batch	2180:2184	arg1	experiments					2197:2207	batch adsorption experiments	2180:2207	batch adsorption experiments	2180:2207	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	7	106	theme	teichoic	1260:1267	arg1	sites					1311:1315	the main sites	1302:1315	the main sites for HREE adsorption	1302:1335	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	7	106	theme	teichoic	1260:1267	arg1	acids					1269:1273	teichoic acids	1260:1273	teichoic acids in the cell wall	1260:1290	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	3	107	theme	exogenic	379:386	arg1	deposits					425:432	regolith-hosted REE deposits	405:432	regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	405:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	3	107	theme	exogenic	379:386	arg1	deposits					388:395	exogenic deposits	379:395	exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand	379:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
35708325	4	108	theme	light	807:811	arg1	LREEs					819:823	LREEs	819:823	LREEs	819:823	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	4	108	theme	light	807:811	arg1	REEs					813:816	light REEs	807:816	light REEs (LREEs)	807:824	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	12	109	theme	sequencing	2168:2177	arg1	combination					2137:2147	a combination	2135:2147	a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization	2135:2243	Using a combination of high-throughput sequencing, batch adsorption experiments, and spectroscopic characterization, the functional microorganisms contributing to REE enrichment and fractionation are disclosed.					
35708325	9	110	theme	supergene	1578:1586	arg1	mineralization					1592:1605	the supergene REE mineralization	1574:1605	the supergene REE mineralization	1574:1605	These findings not only elucidate the crucial contribution of fungi and bacteria in the supergene REE mineralization but also provide insights into efficient utilization of mineral resources via a biological pathway.					
35708325	10	111	theme	metallogenic	1861:1872	arg1	theory					1874:1879	the metallogenic theory	1857:1879	the metallogenic theory	1857:1879	IMPORTANCE Understanding the role of microorganisms in the formation of regolith-hosted rare earth element (REE) deposits is beneficial for improving the metallogenic theory and deposit exploitation, given that such deposits absolutely exist in subtropical regions with strong microbial activities.					
35708325	4	112	theme	REEs	766:769	arg1	enrichment					752:761	the enrichment	748:761	the enrichment of REEs and fractionation between HREEs and light REEs (LREEs)	748:824	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	14	113	theme	above-mentioned	2518:2532	arg1	findings					2534:2541	The above-mentioned findings	2514:2541	The above-mentioned findings	2514:2541	The above-mentioned findings not only unravel the importance of microorganisms in the formation of supergene REE deposits but also provide experimental evidence for the bioutilization of REE resources.					
35708325	13	114	theme	active	2400:2405	arg1	carboxyl					2366:2373	the surface carboxyl and phosphate groups	2354:2394	carboxyl	2366:2373	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	114	theme	active	2400:2405	arg1	groups					2389:2394	the surface carboxyl and phosphate groups	2354:2394	groups	2389:2394	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	13	114	theme	active	2400:2405	arg1	sites					2407:2411	active sites	2400:2411	active sites for REE adsorption	2400:2430	For bacteria, the surface carboxyl and phosphate groups are active sites for REE adsorption, while teichoic acids in the cell walls of G+ bacteria lead to REE fractionation.					
35708325	7	115	theme	adsorbed	1240:1247	arg1	HREEs					1249:1253	preferentially adsorbed HREEs	1225:1253	preferentially adsorbed HREEs	1225:1253	Taking advantage of bacteria strains isolated from the profile, Gram-positive bacteria affiliated with Bacillus and Micrococcus preferentially adsorbed HREEs, and teichoic acids in the cell wall served as the main sites for HREE adsorption, leading to an enrichment of HREEs in the deposit.					
35708325	6	116	theme	key	1042:1044	arg1	role					1046:1049	a key role	1040:1049	a key role	1040:1049	Both fungi and bacteria contributed to the accumulation of REEs, whereas bacteria played a key role in the fractionation between HREEs and LREEs.					
35708325	4	117	theme	fractionation	775:787	arg1	enrichment					752:761	the enrichment	748:761	the enrichment of REEs and fractionation between HREEs and light REEs (LREEs)	748:824	In this study, we characterized the microbial community composition and diversity along a complete weathering profile drilled from a regolith-hosted REE deposit in Southeastern China and report the striking contributions of microorganisms to the enrichment of REEs and fractionation between HREEs and light REEs (LREEs).					
35708325	3	118	theme	global	486:491	arg1	demand					498:503	global HREE demand	486:503	global HREE demand	486:503	However, little is known about the roles of microorganisms in the formation of exogenic deposits such as regolith-hosted REE deposits that are of HREE enrichment and provide over 90% of global HREE demand.					
36442241	0	0	theme	digestion	77:85	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	6	1	theme	chickpea	882:889	arg1	cultivars					891:899	chickpea cultivars	882:899	chickpea cultivars	882:899	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	7	2	theme	p-hydroxybenzoic	1008:1023	arg1	acids					1038:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	0	3	dep	Cicer	116:120	arg1	L.					132:133	Cicer arietinum L.	116:133	Cicer arietinum L.	116:133	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	4	4	theme	type	572:575	arg1	polymorphs					577:586	both A and B type polymorphs	559:586	both A and B type polymorphs	559:586	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	4	5	from	present	593:599	arg1	cultivars					623:631	the chickpea flour cultivars	604:631	the chickpea flour cultivars	604:631	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	7	6	theme	ferulic	1087:1093	arg1	acids					1095:1099	gallic, p-coumaric, and ferulic acids	1063:1099	gallic, p-coumaric, and ferulic acids after germination	1063:1117	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	3	7	theme	non-germinated	496:509	arg1	ones					511:514	the non-germinated ones	492:514	the non-germinated ones	492:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	4	8	theme	B	570:570	arg1	polymorphs					577:586	both A and B type polymorphs	559:586	both A and B type polymorphs	559:586	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	0	9	from	Impact	0:5	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	5	10	dep	25	779:780	arg1	to					776:777	to	776:777	to	776:777	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	6	11	theme	coils	865:869	arg1	content					871:877	random coils content	858:877	random coils content	858:877	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	5	12	theme	relative	672:679	arg1	crystallinity					681:693	the relative crystallinity	668:693	the relative crystallinity of the chickpea flour cultivars	668:725	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	7	13	theme	acid	930:933	arg1	profiling					935:943	Phenolic acid profiling	921:943	Phenolic acid profiling	921:943	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	3	14	dep	%	482:482	arg1	that					484:487	that	484:487	that	484:487	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	1	15	theme	chickpea	261:268	arg1	cultivars					276:284	the chickpea flour cultivars	257:284	the chickpea flour cultivars studied	257:292	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	0	16	theme	chickpea	106:113	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	6	17	theme	random	858:863	arg1	content					871:877	random coils content	858:877	random coils content	858:877	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	7	18	theme	gallic	1063:1068	arg1	acids					1095:1099	gallic, p-coumaric, and ferulic acids	1063:1099	gallic, p-coumaric, and ferulic acids after germination	1063:1117	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	7	19	from	increase	1051:1058	arg1	acids					1095:1099	gallic, p-coumaric, and ferulic acids	1063:1099	gallic, p-coumaric, and ferulic acids after germination	1063:1117	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	7	20	from	decrease	954:961	arg1	concentration					970:982	the concentration	966:982	the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	966:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	0	21	theme	desi	101:104	arg1	Cicer					116:120	Cicer	116:120	Cicer	116:120	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	0	21	theme	desi	101:104	arg1	chickpea					106:113	desi chickpea	101:113	desi chickpea (Cicer arietinum L.)	101:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	2	22	theme	chickpea	395:402	arg1	flour					404:408	germinated chickpea flour	384:408	germinated chickpea flour	384:408	Protein and starch digestibilities were significantly improved in germinated chickpea flour.					
36442241	7	23	theme	Phenolic	921:928	arg1	profiling					935:943	Phenolic acid profiling	921:943	Phenolic acid profiling	921:943	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	3	24	theme	Germinated	411:420	arg1	flour					431:435	Germinated chickpea flour	411:435	Germinated chickpea flour	411:435	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	2	25	theme	germinated	384:393	arg1	flour					404:408	germinated chickpea flour	384:408	germinated chickpea flour	384:408	Protein and starch digestibilities were significantly improved in germinated chickpea flour.					
36442241	1	26	theme	flour	270:274	arg1	cultivars					276:284	the chickpea flour cultivars	257:284	the chickpea flour cultivars studied	257:292	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	1	27	theme	nutrient	183:190	arg1	composition					192:202	the nutrient composition	179:202	the nutrient composition	179:202	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	1	28	theme	cultivars	276:284	arg1	content					220:226	total phenolic content	205:226	total phenolic content	205:226	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	1	28	theme	cultivars	276:284	arg1	activity					245:252	antioxidant activity	233:252	antioxidant activity	233:252	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	1	28	theme	cultivars	276:284	arg1	composition					192:202	the nutrient composition	179:202	the nutrient composition	179:202	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	5	29	theme	flour	711:715	arg1	cultivars					717:725	the chickpea flour cultivars	698:725	the chickpea flour cultivars	698:725	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	4	30	located	present	593:599	arg1	cultivars					623:631	the chickpea flour cultivars	604:631	the chickpea flour cultivars	604:631	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	4	30	located	present	593:599	arg2	polymorphs					577:586	both A and B type polymorphs	559:586	both A and B type polymorphs	559:586	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	0	31	theme	germination	10:20	arg1	Impact					0:5	Impact	0:5	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	0:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	5	32	theme	cultivars	717:725	arg1	crystallinity					681:693	the relative crystallinity	668:693	the relative crystallinity of the chickpea flour cultivars	668:725	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	4	33	from	cultivars	623:631	arg1	present					593:599	present	593:599	present	593:599	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	4	34	theme	flour	617:621	arg1	cultivars					623:631	the chickpea flour cultivars	604:631	the chickpea flour cultivars	604:631	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	3	35	theme	chickpea	422:429	arg1	flour					431:435	Germinated chickpea flour	411:435	Germinated chickpea flour	411:435	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	4	36	theme	A	564:564	arg1	polymorphs					577:586	both A and B type polymorphs	559:586	both A and B type polymorphs	559:586	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	7	37	theme	caffeic	1030:1036	arg1	acids					1038:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	4	38	attach	present	593:599	arg1	cultivars					623:631	the chickpea flour cultivars	604:631	the chickpea flour cultivars	604:631	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	4	38	attach	present	593:599	arg2	polymorphs					577:586	both A and B type polymorphs	559:586	both A and B type polymorphs	559:586	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	1	39	theme	total	205:209	arg1	content					220:226	total phenolic content	205:226	total phenolic content	205:226	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	0	40	theme	structural	25:34	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	4	41	theme	diffraction	523:533	arg1	analysis					535:542	X-ray diffraction analysis	517:542	X-ray diffraction analysis	517:542	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	7	42	theme	acids	1038:1042	arg1	concentration					970:982	the concentration	966:982	the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	966:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	1	43	theme	phenolic	211:218	arg1	content					220:226	total phenolic content	205:226	total phenolic content	205:226	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	4	44	theme	X-ray	517:521	arg1	analysis					535:542	X-ray diffraction analysis	517:542	X-ray diffraction analysis	517:542	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	6	45	from	content	871:877	arg1	β-sheets					845:852	β-sheets	845:852	β-sheets	845:852	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	7	46	theme	p-coumaric	996:1005	arg1	acids					1038:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	2	47	theme	starch	330:335	arg1	digestibilities					337:351	Protein and starch digestibilities	318:351	Protein and starch digestibilities	318:351	Protein and starch digestibilities were significantly improved in germinated chickpea flour.					
36442241	0	48	theme	physicochemical	37:51	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	5	49	dep	27	746:747	arg1	to					743:744	to	743:744	to	743:744	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	6	50	theme	secondary	805:813	arg1	structures					815:824	Protein secondary structures	797:824	Protein secondary structures	797:824	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	1	51	dep	increased	169:177	arg1	GNG-1581					307:314	GNG-1581	307:314	GNG-1581	307:314	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	1	51	dep	increased	169:177	arg1	GNG-469					295:301	GNG-469	295:301	GNG-469	295:301	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
36442241	7	52	theme	p-coumaric	1071:1080	arg1	acids					1095:1099	gallic, p-coumaric, and ferulic acids	1063:1099	gallic, p-coumaric, and ferulic acids after germination	1063:1117	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	6	53	theme	Protein	797:803	arg1	structures					815:824	Protein secondary structures	797:824	Protein secondary structures	797:824	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	7	54	theme	ellagic	987:993	arg1	acids					1038:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids	987:1042	Phenolic acid profiling showed a decrease in the concentration of ellagic, p-coumaric, p-hydroxybenzoic, and caffeic acids but an increase in gallic, p-coumaric, and ferulic acids after germination.					
36442241	0	55	dep	flour	136:140	arg1	Impact					0:5	Impact	0:5	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	0:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	5	56	theme	chickpea	702:709	arg1	cultivars					717:725	the chickpea flour cultivars	698:725	the chickpea flour cultivars	698:725	Germination significantly reduced the relative crystallinity of the chickpea flour cultivars, from around 33 to 27% for GNG 469 and around 30 to 25% for GNG 1581.					
36442241	3	57	contain	had	454:456	arg2	modulus					466:472	a shear modulus	458:472	a shear modulus about 60% that of the non-germinated ones	458:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	3	57	contain	had	454:456	arg1	gels					444:447	gels	444:447	gels that had a shear modulus about 60% that of the non-germinated ones	444:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	2	58	theme	Protein	318:324	arg1	digestibilities					337:351	Protein and starch digestibilities	318:351	Protein and starch digestibilities	318:351	Protein and starch digestibilities were significantly improved in germinated chickpea flour.					
36442241	3	59	theme	shear	460:464	arg1	modulus					466:472	a shear modulus	458:472	a shear modulus about 60% that of the non-germinated ones	458:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	3	60	theme	ones	511:514	arg1	ones					511:514	the non-germinated ones	492:514	the non-germinated ones	492:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	3	60	theme	ones	511:514	arg1	%					482:482	60%	480:482	60% that of the non-germinated ones	480:514	Germinated chickpea flour formed gels that had a shear modulus about 60% that of the non-germinated ones.					
36442241	4	61	theme	chickpea	608:615	arg1	cultivars					623:631	the chickpea flour cultivars	604:631	the chickpea flour cultivars	604:631	X-ray diffraction analysis indicated that both A and B type polymorphs were present in the chickpea flour cultivars.					
36442241	0	62	theme	techno-functional	54:70	arg1	properties					87:96	structural, physicochemical, techno-functional, and digestion properties	25:96	structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.)	25:134	Impact of germination on structural, physicochemical, techno-functional, and digestion properties of desi chickpea (Cicer arietinum L.) flour.					
36442241	6	63	from	increase	833:840	arg1	β-sheets					845:852	β-sheets	845:852	β-sheets	845:852	Protein secondary structures showed increase in β-sheets and random coils content in chickpea cultivars during germination.					
36442241	1	64	theme	antioxidant	233:243	arg1	activity					245:252	antioxidant activity	233:252	antioxidant activity	233:252	Germination significantly increased the nutrient composition, total phenolic content, and antioxidant activity of the chickpea flour cultivars studied (GNG-469 and GNG-1581).					
35450627	2	0	theme	ECF	464:466	arg1	sequence					468:475	ECF sequence	464:475	ECF sequence	464:475	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	4	1	theme	high	824:827	arg1	fraction					844:851	a high molecular mass fraction	822:851	a high molecular mass fraction	822:851	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	1	2	theme	high-purity	178:188	arg1	pulp					212:215	dissolving pulp	201:215	dissolving pulp	201:215	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	1	2	theme	high-purity	178:188	arg1	cellulose					190:198	high-purity cellulose	178:198	high-purity cellulose (dissolving pulp) from birch wood	178:232	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	4	3	theme	hemicelluloses	750:763	arg1	%					741:741	more than 90%	729:741	more than 90% of the hemicelluloses	729:763	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	4	3	theme	hemicelluloses	750:763	arg1	hemicelluloses					750:763	the hemicelluloses	746:763	the hemicelluloses	746:763	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	0	4	theme	IONCELL-P	92:100	arg1	process					102:108	IONCELL-P process	92:108	IONCELL-P process	92:108	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	2	5	theme	paper	343:347	arg1	pulp					355:358	A paper grade pulp	341:358	A paper grade pulp	341:358	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	1	6	theme	/water	268:273	arg1	fractionation					275:287	γ-valerolactone (GVL)/water fractionation	247:287	γ-valerolactone (GVL)/water fractionation	247:287	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	4	7	theme	conventional	886:897	arg1	pulp					903:906	a conventional PHK pulp	884:906	a conventional PHK pulp	884:906	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	3	8	theme	PH-Soda-AQ	681:690	arg1	pulps					693:697	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	pulps	693:697	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	4	9	theme	mass	839:842	arg1	fraction					844:851	a high molecular mass fraction	822:851	a high molecular mass fraction	822:851	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	5	10	theme	cellulose	1028:1036	arg1	acetate					1038:1044	high-viscosity cellulose acetate	1013:1044	high-viscosity cellulose acetate	1013:1044	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	4	11	theme	molecular	829:837	arg1	fraction					844:851	a high molecular mass fraction	822:851	a high molecular mass fraction	822:851	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	2	12	theme	grade	349:353	arg1	pulp					355:358	A paper grade pulp	341:358	A paper grade pulp	341:358	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	2	13	with	cook	390:393	arg1	composition					410:420	a similar composition	400:420	a similar composition to birch kraft pulp	400:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	2	14	theme	GVL	386:388	arg1	cook					390:393	optimal GVL cook	378:393	optimal GVL cook with a similar composition to birch kraft pulp	378:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	4	15	theme	PHK	899:901	arg1	pulp					903:906	a conventional PHK pulp	884:906	a conventional PHK pulp	884:906	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	0	16	from	wood	44:47	arg1	production					22:31	High-purity cellulose production	0:31	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.	0:109	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	2	17	theme	birch	425:429	arg1	pulp					437:440	birch kraft pulp	425:440	birch kraft pulp	425:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	1	18	theme	dissolving	201:210	arg1	pulp					212:215	dissolving pulp	201:215	dissolving pulp	201:215	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	1	18	theme	dissolving	201:210	arg1	cellulose					190:198	high-purity cellulose	178:198	high-purity cellulose (dissolving pulp) from birch wood	178:232	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	0	19	theme	cellulose	12:20	arg1	production					22:31	High-purity cellulose production	0:31	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.	0:109	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	4	20	dep	fraction	844:851	arg1	times					858:862	times	858:862	times	858:862	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	5	21	theme	friendly	1105:1112	arg1	way					1114:1116	an environmentally friendly way	1086:1116	an environmentally friendly way	1086:1116	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	0	22	theme	High-purity	0:10	arg1	production					22:31	High-purity cellulose production	0:31	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.	0:109	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	1	23	theme	ionic	293:297	arg1	treatment					306:314	ionic liquid treatment	293:314	ionic liquid treatment	293:314	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	4	24	theme	%	816:816	arg1	purity					804:809	a purity	802:809	a purity of 96%	802:816	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	1	25	theme	liquid	299:304	arg1	treatment					306:314	ionic liquid treatment	293:314	ionic liquid treatment	293:314	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	5	26	theme	high-viscosity	1013:1026	arg1	acetate					1038:1044	high-viscosity cellulose acetate	1013:1044	high-viscosity cellulose acetate	1013:1044	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	5	27	theme	regenerated	948:958	arg1	fibers					970:975	regenerated cellulose fibers	948:975	regenerated cellulose fibers	948:975	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	2	28	theme	similar	402:408	arg1	composition					410:420	a similar composition	400:420	a similar composition to birch kraft pulp	400:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	2	29	theme	IONCELL-P	526:534	arg1	process					536:542	the IONCELL-P process	522:542	the IONCELL-P process	522:542	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	1	30	theme	birch	223:227	arg1	wood					229:232	birch wood	223:232	birch wood	223:232	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	5	31	theme	conventional	1121:1132	arg1	processes					1134:1142	conventional processes	1121:1142	conventional processes	1121:1142	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	3	32	theme	pulp	570:573	arg1	purity					549:554	The purity	545:554	The purity of the GVL-IP pulp	545:573	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	4	33	with	fraction	844:851	arg1	purity					804:809	a purity	802:809	a purity of 96%	802:816	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	0	34	theme	birch	38:42	arg1	wood					44:47	birch wood	38:47	birch wood	38:47	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	1	35	theme	pulp	319:322	arg1	treatment					306:314	ionic liquid treatment	293:314	ionic liquid treatment	293:314	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	1	35	theme	pulp	319:322	arg1	fractionation					275:287	γ-valerolactone (GVL)/water fractionation	247:287	γ-valerolactone (GVL)/water fractionation	247:287	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	3	36	theme	prehydrolysis	617:629	arg1	PHK					638:640	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	PHK	638:640	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	5	37	theme	cellulose	960:968	arg1	fibers					970:975	regenerated cellulose fibers	948:975	regenerated cellulose fibers	948:975	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	1	38	from	wood	229:232	arg1	pulp					212:215	dissolving pulp	201:215	dissolving pulp	201:215	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	1	38	from	wood	229:232	arg1	cellulose					190:198	high-purity cellulose	178:198	high-purity cellulose (dissolving pulp) from birch wood	178:232	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	0	39	theme	γ-valerolactone/water	52:72	arg1	fractionation					74:86	γ-valerolactone/water fractionation	52:86	γ-valerolactone/water fractionation	52:86	High-purity cellulose production from birch wood by γ-valerolactone/water fractionation and IONCELL-P process.					
35450627	3	40	theme	kraft	631:635	arg1	PHK					638:640	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	PHK	638:640	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	5	41	theme	GVL-IP	909:914	arg1	pulps					916:920	GVL-IP pulps	909:920	GVL-IP pulps	909:920	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	4	42	theme	IONCELL-P	700:708	arg1	extraction					710:719	IONCELL-P extraction	700:719	IONCELL-P extraction	700:719	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	3	43	theme	prehydrolysis	647:659	arg1	pulps					693:697	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	pulps	693:697	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	3	44	theme	GVL-IP	563:568	arg1	pulp					570:573	the GVL-IP pulp	559:573	the GVL-IP pulp	559:573	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	1	45	theme	environmentally	134:148	arg1	process					159:165	an environmentally friendly process	131:165	an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP)	131:338	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	5	46	theme	environmentally	1089:1103	arg1	way					1114:1116	an environmentally friendly way	1086:1116	an environmentally friendly way	1086:1116	GVL-IP pulps are suitable not only for regenerated cellulose fibers or films, but also for high-purity, high-viscosity cellulose acetate and ethers, which cannot be produced in an environmentally friendly way by conventional processes.					
35450627	3	47	theme	soda-anthraquinone	661:678	arg1	pulps					693:697	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	pulps	693:697	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	1	48	theme	friendly	150:157	arg1	process					159:165	an environmentally friendly process	131:165	an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP)	131:338	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	4	49	theme	2.3	854:856	arg1	times					858:862	times	858:862	times	858:862	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	3	50	theme	commercial	606:615	arg1	PHK					638:640	commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps	606:697	PHK	638:640	The purity of the GVL-IP pulp significantly exceeded that of commercial prehydrolysis kraft (PHK) and prehydrolysis soda-anthraquinone (PH-Soda-AQ) pulps.					
35450627	1	51	theme	γ-valerolactone	247:261	arg1	fractionation					275:287	γ-valerolactone (GVL)/water fractionation	247:287	γ-valerolactone (GVL)/water fractionation	247:287	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
35450627	4	52	dep	times	858:862	arg1	higher					864:869	higher	864:869	higher	864:869	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	4	53	theme	dissolving	781:790	arg1	pulp					792:795	a dissolving pulp	779:795	a dissolving pulp with a purity of 96%	779:816	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	2	54	theme	optimal	378:384	arg1	cook					390:393	optimal GVL cook	378:393	optimal GVL cook with a similar composition to birch kraft pulp	378:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	4	55	with	pulp	792:795	arg1	purity					804:809	a purity	802:809	a purity of 96%	802:816	IONCELL-P extraction removed more than 90% of the hemicelluloses, resulting in a dissolving pulp with a purity of 96% and a high molecular mass fraction, 2.3 times higher than that of a conventional PHK pulp.					
35450627	2	56	theme	kraft	431:435	arg1	pulp					437:440	birch kraft pulp	425:440	birch kraft pulp	425:440	A paper grade pulp was produced from optimal GVL cook with a similar composition to birch kraft pulp and was bleached with ECF sequence before the hemicelluloses were removed using the IONCELL-P process.					
35450627	1	57	theme	GVL	264:266	arg1	fractionation					275:287	γ-valerolactone (GVL)/water fractionation	247:287	γ-valerolactone (GVL)/water fractionation	247:287	This study presents an environmentally friendly process to produce high-purity cellulose (dissolving pulp) from birch wood by combining γ-valerolactone (GVL)/water fractionation and ionic liquid treatment of pulp, IONCELL-P (IP).					
36871680	0	0	theme	hydrophilic	93:103	arg1	composites					105:114	hydrophilic composites	93:114	hydrophilic composites with enhanced functional properties	93:150	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	2	1	theme	dependent	536:544	arg1	dispersibility					494:507	water dispersibility	488:507	water dispersibility	488:507	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	1	theme	dependent	536:544	arg1	Mw					603:604	Mw	603:604	Mw	603:604	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	1	2	theme	much	204:207	arg1	attention					209:217	much attention	204:217	much attention	204:217	Protein-polysaccharide interactions have attracted much attention due to inherent potential in generating new structures and functionalities.					
36871680	3	3	theme	RPs/CMC	701:707	arg1	ratio					714:718	a RPs/CMC mass ratio	699:718	a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa)	699:759	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	6	4	theme	controllable	1063:1074	arg1	functionalities					1076:1090	highly controllable functionalities	1056:1090	highly controllable functionalities in terms of emulsifying and foaming properties	1056:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	3	5	dep	%	684:684	arg1	to					686:687	to	686:687	to	686:687	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	2	6	theme	CMC	610:612	arg1	dispersibility					494:507	water dispersibility	488:507	water dispersibility	488:507	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	6	theme	CMC	610:612	arg1	Mw					603:604	Mw	603:604	Mw	603:604	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	6	theme	CMC	610:612	arg1	weight					595:600	molecular weight	585:600	molecular weight	585:600	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	6	theme	CMC	610:612	arg1	functionalities					513:527	functionalities	513:527	functionalities	513:527	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	7	theme	rice	334:337	arg1	RPs					349:351	RPs	349:351	RPs	349:351	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	7	theme	rice	334:337	arg1	proteins					339:346	rice proteins	334:346	rice proteins (RPs)	334:352	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	8	theme	substitution	563:574	arg1	degree					553:558	the degree	549:558	the degree of substitution (DS)	549:579	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	6	9	with	matrix	1197:1202	arg1	structures					1220:1229	customized structures	1209:1229	customized structures	1209:1229	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	6	9	with	matrix	1197:1202	arg1	textures					1235:1242	textures	1235:1242	textures	1235:1242	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	0	10	theme	functional	130:139	arg1	properties					141:150	enhanced functional properties	121:150	enhanced functional properties	121:150	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	3	11	theme	10:1	723:726	arg1	ratio					714:718	a RPs/CMC mass ratio	699:718	a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa)	699:759	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	6	12	theme	promising	1155:1163	arg1	applications					1165:1176	promising applications	1155:1176	promising applications	1155:1176	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	2	13	theme	novel	422:426	arg1	complexes					451:459	novel protein-polysaccharide complexes	422:459	novel protein-polysaccharide complexes (RCs)	422:465	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	13	theme	novel	422:426	arg1	RCs					462:464	RCs	462:464	RCs	462:464	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	0	14	theme	enhanced	121:128	arg1	properties					141:150	enhanced functional properties	121:150	enhanced functional properties	121:150	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	3	15	theme	mass	709:712	arg1	ratio					714:718	a RPs/CMC mass ratio	699:718	a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa)	699:759	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	4	16	theme	dichroism	788:796	arg1	spectra					798:804	Fluorescence and circular dichroism spectra	762:804	spectra	798:804	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	5	17	with	CMC	996:998	arg1	DS					1014:1015	a larger DS	1005:1015	a larger DS	1005:1015	Furthermore, the structures of RCs became more unfolded for CMC with a larger DS or a smaller Mw.					
36871680	5	17	with	CMC	996:998	arg1	Mw					1030:1031	a smaller Mw	1020:1031	a smaller Mw	1020:1031	Furthermore, the structures of RCs became more unfolded for CMC with a larger DS or a smaller Mw.					
36871680	1	18	theme	inherent	226:233	arg1	potential					235:243	inherent potential	226:243	inherent potential in generating new structures and functionalities	226:292	Protein-polysaccharide interactions have attracted much attention due to inherent potential in generating new structures and functionalities.					
36871680	6	19	theme	food	1192:1195	arg1	matrix					1197:1202	food matrix	1192:1202	food matrix with customized structures and textures	1192:1242	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	4	20	theme	RPs	844:846	arg1	tendency					832:839	suppressed folding tendency	813:839	suppressed folding tendency of RPs by CMC	813:853	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	2	21	theme	prior	400:404	arg1	neutralization					406:419	pH 12.0 prior neutralization	392:419	pH 12.0 prior neutralization	392:419	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	3	22	theme	DS1.2	740:744	arg1	CMC					733:735	CMC	733:735	CMC of DS1.2 (Mw = 250 kDa)	733:759	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	2	23	theme	molecular	585:593	arg1	weight					595:600	molecular weight	585:600	molecular weight	585:600	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	0	24	with	composites	105:114	arg1	properties					141:150	enhanced functional properties	121:150	enhanced functional properties	121:150	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	5	25	theme	RCs	967:969	arg1	structures					953:962	the structures	949:962	the structures of RCs	949:969	Furthermore, the structures of RCs became more unfolded for CMC with a larger DS or a smaller Mw.					
36871680	0	26	theme	electrostatic	11:23	arg1	interaction					25:35	the electrostatic interaction	7:35	the electrostatic interaction between rice protein and carboxymethyl cellulose	7:84	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	4	27	theme	protein	913:919	arg1	conformations					921:933	controllable protein conformations	900:933	controllable protein conformations	900:933	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	6	28	with	RCs	1047:1049	arg1	functionalities					1076:1090	highly controllable functionalities	1056:1090	highly controllable functionalities in terms of emulsifying and foaming properties	1056:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	6	29	theme	properties	1128:1137	arg1	terms					1095:1099	terms	1095:1099	terms of emulsifying and foaming properties	1095:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	0	30	theme	rice	45:48	arg1	protein					50:56	rice protein	45:56	rice protein	45:56	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	5	31	theme	larger	1007:1012	arg1	DS					1014:1015	a larger DS	1005:1015	a larger DS	1005:1015	Furthermore, the structures of RCs became more unfolded for CMC with a larger DS or a smaller Mw.					
36871680	1	32	theme	new	259:261	arg1	structures					263:272	new structures	259:272	new structures	259:272	Protein-polysaccharide interactions have attracted much attention due to inherent potential in generating new structures and functionalities.					
36871680	3	33	theme	RPs	657:659	arg1	water-dispersibility					633:652	the water-dispersibility	629:652	the water-dispersibility of RPs	629:659	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	2	34	theme	protein-polysaccharide	428:449	arg1	complexes					451:459	novel protein-polysaccharide complexes	422:459	novel protein-polysaccharide complexes (RCs)	422:465	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	34	theme	protein-polysaccharide	428:449	arg1	RCs					462:464	RCs	462:464	RCs	462:464	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	4	35	theme	folding	824:830	arg1	tendency					832:839	suppressed folding tendency	813:839	suppressed folding tendency of RPs by CMC	813:853	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	6	36	theme	emulsifying	1104:1114	arg1	properties					1128:1137	emulsifying and foaming properties	1104:1137	emulsifying and foaming properties	1104:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	6	37	theme	foaming	1120:1126	arg1	properties					1128:1137	emulsifying and foaming properties	1104:1137	emulsifying and foaming properties	1104:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	2	38	theme	water	488:492	arg1	dispersibility					494:507	water dispersibility	488:507	water dispersibility	488:507	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	38	theme	water	488:492	arg1	Mw					603:604	Mw	603:604	Mw	603:604	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	5	39	theme	smaller	1022:1028	arg1	Mw					1030:1031	a smaller Mw	1020:1031	a smaller Mw	1020:1031	Furthermore, the structures of RCs became more unfolded for CMC with a larger DS or a smaller Mw.					
36871680	4	40	theme	suppressed	813:822	arg1	tendency					832:839	suppressed folding tendency	813:839	suppressed folding tendency of RPs by CMC	813:853	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	6	41	theme	customized	1209:1218	arg1	structures					1220:1229	customized structures	1209:1229	customized structures	1209:1229	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	4	42	theme	controllable	900:911	arg1	conformations					921:933	controllable protein conformations	900:933	controllable protein conformations	900:933	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	3	43	theme	93.5 	689:693	arg1	%					684:684	%	684:684	%	684:684	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	1	44	theme	Protein-polysaccharide	153:174	arg1	interactions					176:187	Protein-polysaccharide interactions	153:187	Protein-polysaccharide interactions	153:187	Protein-polysaccharide interactions have attracted much attention due to inherent potential in generating new structures and functionalities.					
36871680	6	45	contain	have	1150:1153	arg1	RCs					1047:1049	RCs	1047:1049	RCs	1047:1049	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	6	45	contain	have	1150:1153	arg2	applications					1165:1176	promising applications	1155:1176	promising applications	1155:1176	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	3	46	theme	1.7 	680:683	arg1	%					684:684	%	684:684	%	684:684	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	4	47	theme	Fluorescence	762:773	arg1	spectra					798:804	Fluorescence and circular dichroism spectra	762:804	spectra	798:804	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
36871680	6	48	from	functionalities	1076:1090	arg1	terms					1095:1099	terms	1095:1099	terms of emulsifying and foaming properties	1095:1137	This enabled RCs with highly controllable functionalities in terms of emulsifying and foaming properties, which may have promising applications in developing food matrix with customized structures and textures.					
36871680	2	49	theme	carboxymethyl	359:371	arg1	cellulose					373:381	carboxymethyl cellulose	359:381	carboxymethyl cellulose (CMC)	359:387	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	49	theme	carboxymethyl	359:371	arg1	CMC					384:386	CMC	384:386	CMC	384:386	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	2	50	theme	present	302:308	arg1	study					310:314	the present study	298:314	the present study	298:314	In the present study, by simply mixing rice proteins (RPs) with carboxymethyl cellulose (CMC) at pH 12.0 prior neutralization, novel protein-polysaccharide complexes (RCs) were structured with water dispersibility and functionalities highly dependent on the degree of substitution (DS) and molecular weight (Mw) of CMC.					
36871680	3	51	with	10:1	723:726	arg1	CMC					733:735	CMC	733:735	CMC of DS1.2 (Mw = 250 kDa)	733:759	Specifically, the water-dispersibility of RPs was increased from 1.7 % to 93.5 % at a RPs/CMC mass ratio of 10:1 with CMC of DS1.2 (Mw = 250 kDa).					
36871680	0	52	theme	carboxymethyl	62:74	arg1	cellulose					76:84	carboxymethyl cellulose	62:84	carboxymethyl cellulose	62:84	Tuning the electrostatic interaction between rice protein and carboxymethyl cellulose toward hydrophilic composites with enhanced functional properties.					
36871680	4	53	theme	circular	779:786	arg1	spectra					798:804	Fluorescence and circular dichroism spectra	762:804	spectra	798:804	Fluorescence and circular dichroism spectra showed suppressed folding tendency of RPs by CMC during neutralizing the basicity, indicating controllable protein conformations.					
37322033	5	0	theme	high	724:727	arg1	content					739:745	high cellulose content	724:745	high cellulose content	724:745	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	5	1	dep	%	775:775	arg1	i.e.					765:768	i.e.	765:768	i.e.	765:768	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	9	2	theme	CPS	1246:1248	arg1	fibers					1250:1255	CPS fibers	1246:1255	CPS fibers	1246:1255	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	2	3	theme	potent	299:304	arg1	it					291:292	it	291:292	it	291:292	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	2	3	theme	potent	299:304	arg1	fiber					318:322	a potent alternative fiber	297:322	a potent alternative fiber for the plant fiber-based industries	297:359	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	5	4	theme	constituent	694:704	arg1	analysis					706:713	chemical constituent analysis	685:713	chemical constituent analysis	685:713	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	1	5	theme	plant	225:229	arg1	stem					203:206	the stem	199:206	the stem of an unexplored plant of Cyperus platystylis R.Br	199:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	5	6	theme	cellulose	729:737	arg1	content					739:745	high cellulose content	724:745	high cellulose content	724:745	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	6	7	dep	2.28 nm	930:936	arg1	i.e.					924:927	i.e.	924:927	i.e.	924:927	Scherrer's equation has been used to determine crystallite size i.e., 2.28 nm.					
37322033	10	8	theme	suitable	1358:1365	arg1	fibers					1330:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	8	theme	suitable	1358:1365	arg1	material					1381:1388	a suitable reinforcement material	1356:1388	a suitable reinforcement material for the bio-composites used in semi-structural applications	1356:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	5	9	from	case	841:844	arg1	moderate					825:832	moderate	825:832	moderate	825:832	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	7	10	theme	fiber	979:983	arg1	382.0					990:994	382.0	990:994	382.0	990:994	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	7	10	theme	fiber	979:983	arg1	diameter					959:966	diameter	959:966	diameter	959:966	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	7	10	theme	fiber	979:983	arg1	length					948:953	mean length	943:953	mean length	943:953	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	9	11	dep	346.16 J.	1205:1213	arg1	revealed					1232:1239	revealed	1232:1239	revealed that CPS fibers have thermal stability up to 279 °C	1232:1291	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	4	12	theme	CPS	525:527	arg1	fiber					529:533	CPS fiber	525:533	CPS fiber	525:533	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	0	13	theme	Cyperus	87:93	arg1	R.Br					107:110	Cyperus platystylis R.Br	87:110	Cyperus platystylis R.Br	87:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	0	14	from	Characterization	0:15	arg1	stem					79:82	the stem	75:82	the stem of Cyperus platystylis R.Br	75:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	5	15	theme	chemical	685:692	arg1	analysis					706:713	chemical constituent analysis	685:713	chemical constituent analysis	685:713	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	10	16	theme	Cyperus	1305:1311	arg1	fibers					1330:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	16	theme	Cyperus	1305:1311	arg1	material					1381:1388	a suitable reinforcement material	1356:1388	a suitable reinforcement material for the bio-composites used in semi-structural applications	1356:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	17	dep	Cyperus	1305:1311	arg1	platystylis					1313:1323	platystylis	1313:1323	platystylis	1313:1323	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	1	18	theme	Cyperus	234:240	arg1	R.Br					254:257	Cyperus platystylis R.Br	234:257	Cyperus platystylis R.Br	234:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	9	19	dep	279 °C	1286:1291	arg1	up					1280:1281	up	1280:1281	up	1280:1281	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	10	20	theme	unique	1298:1303	arg1	fibers					1330:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	20	theme	unique	1298:1303	arg1	material					1381:1388	a suitable reinforcement material	1356:1388	a suitable reinforcement material for the bio-composites used in semi-structural applications	1356:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	21	contain	have	1461:1464	arg1	they					1456:1459	they	1456:1459	they	1456:1459	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	21	contain	have	1461:1464	arg2	qualities					1484:1492	higher functional qualities	1466:1492	higher functional qualities	1466:1492	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	1	22	theme	platystylis	242:252	arg1	R.Br					254:257	Cyperus platystylis R.Br	234:257	Cyperus platystylis R.Br	234:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	0	23	theme	R.Br	107:110	arg1	stem					79:82	the stem	75:82	the stem of Cyperus platystylis R.Br	75:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	4	24	theme	Transformed	607:617	arg1	analysis					653:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	2	25	theme	fiber-based	338:348	arg1	industries					350:359	the plant fiber-based industries	328:359	the plant fiber-based industries	328:359	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	0	26	theme	platystylis	95:105	arg1	R.Br					107:110	Cyperus platystylis R.Br	87:110	Cyperus platystylis R.Br	87:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	9	27	theme	Thermal	1215:1221	arg1	analysis					1223:1230	Thermal analysis	1215:1230	Thermal analysis	1215:1230	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	3	28	theme	CPS	362:364	arg1	fiber					366:370	CPS fiber	362:370	CPS fiber	362:370	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	4	29	dep	Infrared	619:626	arg1	FTIR					629:632	FTIR	629:632	FTIR	629:632	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	1	30	theme	natural	161:167	arg1	fiber					169:173	a natural fiber	159:173	a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br	159:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	8	31	theme	young	1104:1108	arg1	modulus					1112:1118	young's modulus	1104:1118	young's modulus	1104:1118	The maximum tensile strength was obtained at 657 ± 58.8 MPa for 50 mm fiber and young's modulus 88.76 ± 30.42 MPa for 50 mm fiber.					
37322033	4	32	theme	groups	515:520	arg1	presence					482:489	The presence	478:489	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.	478:661	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	10	33	theme	reinforcement	1367:1379	arg1	fibers					1330:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	33	theme	reinforcement	1367:1379	arg1	material					1381:1388	a suitable reinforcement material	1356:1388	a suitable reinforcement material for the bio-composites used in semi-structural applications	1356:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	4	34	theme	functional	504:513	arg1	groups					515:520	different functional groups	494:520	different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin	494:576	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	1	35	theme	fiber	169:173	arg1	characterization					139:154	the characterization	135:154	the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br	135:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	4	36	from	groups	515:520	arg1	fiber					529:533	CPS fiber	525:533	CPS fiber	525:533	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	1	37	theme	R.Br	254:257	arg1	plant					225:229	an unexplored plant	211:229	an unexplored plant of Cyperus platystylis R.Br	211:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
37322033	10	38	theme	functional	1473:1482	arg1	qualities					1484:1492	higher functional qualities	1466:1492	higher functional qualities	1466:1492	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	4	39	theme	Fourier	599:605	arg1	analysis					653:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	0	40	theme	new	22:24	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	4	41	theme	different	494:502	arg1	groups					515:520	different functional groups	494:520	different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin	494:576	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	10	42	theme	stem	1325:1328	arg1	fibers					1330:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers	1294:1335	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	10	42	theme	stem	1325:1328	arg1	material					1381:1388	a suitable reinforcement material	1356:1388	a suitable reinforcement material for the bio-composites used in semi-structural applications	1356:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	9	43	theme	thermal	1262:1268	arg1	stability					1270:1278	thermal stability	1262:1278	thermal stability	1262:1278	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	10	44	theme	semi-structural	1421:1435	arg1	applications					1437:1448	semi-structural applications	1421:1448	semi-structural applications	1421:1448	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	0	45	from	stem	79:82	arg1	Characterization					0:15	Characterization	0:15	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.	0:111	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	0	45	from	stem	79:82	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	3	46	theme	chemical	412:419	arg1	characteristics					461:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	0	47	theme	novel	34:38	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	4	48	theme	Spectrophotometer	635:651	arg1	analysis					653:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	7	49	theme	CPS	975:977	arg1	fiber					979:983	the CPS fiber	971:983	the CPS fiber	971:983	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	5	50	theme	X-ray	663:667	arg1	diffraction					669:679	X-ray diffraction	663:679	X-ray diffraction	663:679	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	0	51	theme	natural	26:32	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	4	52	from	presence	482:489	arg1	fiber					529:533	CPS fiber	525:533	CPS fiber	525:533	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	9	53	theme	required	1159:1166	arg1	energy					1168:1173	The required energy	1155:1173	The required energy to break	1155:1182	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	5	54	theme	fiber	853:857	arg1	case					841:844	the case	837:844	the case of CPS fiber	837:857	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	7	55	theme	mean	943:946	arg1	382.0					990:994	382.0	990:994	382.0	990:994	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	7	55	theme	mean	943:946	arg1	length					948:953	mean length	943:953	mean length	943:953	The mean length and diameter of the CPS fiber were 382.0 and 23.36 μm, respectively.					
37322033	3	56	theme	physical	402:409	arg1	characteristics					461:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	0	57	theme	fiber	55:59	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	6	58	used	used	889:892	arg2	equation					871:878	Scherrer's equation	860:878	Scherrer's equation	860:878	Scherrer's equation has been used to determine crystallite size i.e., 2.28 nm.					
37322033	5	59	theme	CPS	849:851	arg1	fiber					853:857	CPS fiber	849:857	CPS fiber	849:857	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	0	60	theme	lignocellulose	40:53	arg1	resource					61:68	a new natural novel lignocellulose fiber resource	20:68	a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br	20:110	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	9	61	contain	have	1257:1260	arg1	fibers					1250:1255	CPS fibers	1246:1255	CPS fibers	1246:1255	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	9	61	contain	have	1257:1260	arg2	stability					1270:1278	thermal stability	1262:1278	thermal stability	1262:1278	The required energy to break has been recorded at 346.16 J. Thermal analysis revealed that CPS fibers have thermal stability up to 279 °C.					
37322033	3	62	theme	mechanical	431:440	arg1	characteristics					461:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	8	63	theme	tensile	1036:1042	arg1	strength					1044:1051	The maximum tensile strength	1024:1051	The maximum tensile strength	1024:1051	The maximum tensile strength was obtained at 657 ± 58.8 MPa for 50 mm fiber and young's modulus 88.76 ± 30.42 MPa for 50 mm fiber.					
37322033	4	64	theme	Infrared	619:626	arg1	analysis					653:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	Fourier Transformed Infrared (FTIR) Spectrophotometer analysis	599:660	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	2	65	dep	aim	274:276	arg1	CPS					261:263	CPS	261:263	CPS	261:263	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	4	66	from	fiber	529:533	arg1	presence					482:489	The presence	478:489	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.	478:661	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	8	67	theme	maximum	1028:1034	arg1	strength					1044:1051	The maximum tensile strength	1024:1051	The maximum tensile strength	1024:1051	The maximum tensile strength was obtained at 657 ± 58.8 MPa for 50 mm fiber and young's modulus 88.76 ± 30.42 MPa for 50 mm fiber.					
37322033	8	68	theme	50 mm	1088:1092	arg1	fiber					1094:1098	50 mm fiber	1088:1098	50 mm fiber	1088:1098	The maximum tensile strength was obtained at 657 ± 58.8 MPa for 50 mm fiber and young's modulus 88.76 ± 30.42 MPa for 50 mm fiber.					
37322033	3	69	theme	thermal	422:428	arg1	characteristics					461:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	10	70	theme	higher	1466:1471	arg1	qualities					1484:1492	higher functional qualities	1466:1492	higher functional qualities	1466:1492	The unique Cyperus platystylis stem fibers could therefore be a suitable reinforcement material for the bio-composites used in semi-structural applications since they have higher functional qualities.					
37322033	4	71	dep	cellulose	541:549	arg1	i.e.					535:538	i.e.	535:538	i.e.	535:538	The presence of different functional groups in CPS fiber i.e., cellulose, hemicellulose, and lignin which was ensured by Fourier Transformed Infrared (FTIR) Spectrophotometer analysis.					
37322033	5	72	from	moderate	825:832	arg1	case					841:844	the case	837:844	the case of CPS fiber	837:857	X-ray diffraction and chemical constituent analysis revealed high cellulose content and crystallinity i.e., 66.1% and 41.12% respectively, which is comparatively moderate in the case of CPS fiber.					
37322033	3	73	theme	morphological	447:459	arg1	characteristics					461:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	its physical, chemical, thermal, mechanical, and morphological characteristics	398:475	CPS fiber has been investigated for its physical, chemical, thermal, mechanical, and morphological characteristics.					
37322033	2	74	theme	plant	332:336	arg1	industries					350:359	the plant fiber-based industries	328:359	the plant fiber-based industries	328:359	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	8	75	dep	fiber	1094:1098	arg1	88.76 ± 30.42 MPa					1120:1136	88.76 ± 30.42 MPa	1120:1136	88.76 ± 30.42 MPa	1120:1136	The maximum tensile strength was obtained at 657 ± 58.8 MPa for 50 mm fiber and young's modulus 88.76 ± 30.42 MPa for 50 mm fiber.					
37322033	0	76	theme	resource	61:68	arg1	Characterization					0:15	Characterization	0:15	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.	0:111	Characterization of a new natural novel lignocellulose fiber resource from the stem of Cyperus platystylis R.Br.					
37322033	6	77	theme	crystallite	907:917	arg1	size					919:922	crystallite size	907:922	crystallite size	907:922	Scherrer's equation has been used to determine crystallite size i.e., 2.28 nm.					
37322033	2	78	theme	alternative	306:316	arg1	it					291:292	it	291:292	it	291:292	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	2	78	theme	alternative	306:316	arg1	fiber					318:322	a potent alternative fiber	297:322	a potent alternative fiber for the plant fiber-based industries	297:359	(CPS) with an aim to establish it as a potent alternative fiber for the plant fiber-based industries.					
37322033	1	79	theme	unexplored	214:223	arg1	plant					225:229	an unexplored plant	211:229	an unexplored plant of Cyperus platystylis R.Br	211:257	This study deals with the characterization of a natural fiber which is extracted from the stem of an unexplored plant of Cyperus platystylis R.Br.					
36528118	7	0	theme	variable	1220:1227	arg1	effects					1237:1243	the variable isotope effects	1216:1243	the variable isotope effects	1216:1243	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	4	1	theme	mutations	653:661	arg1	types					644:648	four different types	629:648	four different types of mutations that cause impaired starch synthesis	629:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	1	2	theme	organic	149:155	arg1	compounds					157:165	plant derived organic compounds	135:165	plant derived organic compounds	135:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	7	3	theme	isotope	1229:1235	arg1	effects					1237:1243	the variable isotope effects	1216:1243	the variable isotope effects	1216:1243	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	5	4	theme	starch	887:892	arg1	synthesis					894:902	impaired starch synthesis	878:902	impaired starch synthesis	878:902	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	1	5	theme	compounds	157:165	arg1	tool					180:183	a useful tool	171:183	a useful tool for ecological, environmental, and palaeoclimatological research	171:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	5	theme	compounds	157:165	arg1	δ2H					127:129	δ2H	127:129	δ2H	127:129	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	5	theme	compounds	157:165	arg1	analyses					117:124	Hydrogen stable isotope analyses	93:124	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds	93:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	5	6	theme	impaired	878:885	arg1	synthesis					894:902	impaired starch synthesis	878:902	impaired starch synthesis	878:902	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	9	7	theme	impaired	1534:1541	arg1	synthesis					1550:1558	impaired starch synthesis	1534:1558	impaired starch synthesis	1534:1558	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	3	8	theme	plant	528:532	arg1	species					534:540	plant species	528:540	plant species	528:540	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	2	9	theme	variable	295:302	arg1	2H-fractionation					317:332	variable biosynthetic 2H-fractionation	295:332	variable biosynthetic 2H-fractionation	295:332	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	8	10	theme	atoms	1402:1406	arg1	incorporation					1374:1386	incorporation	1374:1386	incorporation of specific H atoms from precursor molecules	1374:1431	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	4	11	theme	carbon	733:738	arg1	metabolism					740:749	carbon metabolism	733:749	carbon metabolism	733:749	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	8	12	theme	precursor	1413:1421	arg1	molecules					1423:1431	precursor molecules	1413:1431	precursor molecules	1413:1431	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	3	13	theme	compounds	481:489	arg1	patterns					463:470	the δ2H patterns	455:470	the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs	455:566	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	7	14	theme	effects	1237:1243	arg1	pathway					1166:1172	the biosynthetic pathway	1149:1172	the biosynthetic pathway of each compound	1149:1189	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	7	14	theme	effects	1237:1243	arg1	source					1206:1211	the likely source	1195:1211	the likely source of the variable isotope effects	1195:1243	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	8	15	theme	2H-fractionation	1319:1334	arg1	sensitivity					1282:1292	the sensitivity	1278:1292	the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism	1278:1361	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	7	16	theme	likely	1199:1204	arg1	source					1206:1211	the likely source	1195:1211	the likely source of the variable isotope effects	1195:1243	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	8	17	theme	biosynthetic	1306:1317	arg1	2H-fractionation					1319:1334	variable biosynthetic 2H-fractionation	1297:1334	variable biosynthetic 2H-fractionation	1297:1334	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	4	18	theme	lipid	834:838	arg1	synthesis					840:848	acetogenic lipid synthesis	823:848	acetogenic lipid synthesis	823:848	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	6	19	theme	metabolic	1078:1086	arg1	sensitivity					1088:1098	strong metabolic sensitivity	1071:1098	strong metabolic sensitivity	1071:1098	By contrast, 2H-fractionation during acetogenic lipid biosynthesis generally did not show strong metabolic sensitivity.					
36528118	2	20	theme	compound	275:282	arg1	synthesis					284:292	organic compound synthesis	267:292	organic compound synthesis	267:292	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	5	21	theme	higher	915:920	arg1	values					947:952	higher cellulose and phytol δ2H values	915:952	higher cellulose and phytol δ2H values	915:952	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	2	22	theme	carbon	394:399	arg1	fluxes					401:406	plant carbon fluxes	388:406	plant carbon fluxes	388:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	7	23	theme	biosynthetic	1153:1164	arg1	pathway					1166:1172	the biosynthetic pathway	1149:1172	the biosynthetic pathway of each compound	1149:1189	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	4	24	theme	acetogenic	823:832	arg1	synthesis					840:848	acetogenic lipid synthesis	823:848	acetogenic lipid synthesis	823:848	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	2	25	theme	organic	267:273	arg1	synthesis					284:292	organic compound synthesis	267:292	organic compound synthesis	267:292	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	2	26	theme	plant	388:392	arg1	fluxes					401:406	plant carbon fluxes	388:406	plant carbon fluxes	388:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	0	27	theme	metabolic	4:12	arg1	sensitivity					14:24	The metabolic sensitivity	0:24	The metabolic sensitivity of hydrogen isotope fractionation	0:58	The metabolic sensitivity of hydrogen isotope fractionation differs between plant compounds.					
36528118	9	28	theme	starch	1543:1548	arg1	synthesis					1550:1558	impaired starch synthesis	1534:1558	impaired starch synthesis	1534:1558	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	4	29	from	variability	718:728	arg1	metabolism					740:749	carbon metabolism	733:749	carbon metabolism	733:749	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	1	30	theme	Hydrogen	93:100	arg1	tool					180:183	a useful tool	171:183	a useful tool for ecological, environmental, and palaeoclimatological research	171:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	30	theme	Hydrogen	93:100	arg1	δ2H					127:129	δ2H	127:129	δ2H	127:129	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	30	theme	Hydrogen	93:100	arg1	analyses					117:124	Hydrogen stable isotope analyses	93:124	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds	93:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	8	31	from	molecules	1423:1431	arg1	incorporation					1374:1386	incorporation	1374:1386	incorporation of specific H atoms from precursor molecules	1374:1431	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	1	32	theme	useful	173:178	arg1	tool					180:183	a useful tool	171:183	a useful tool for ecological, environmental, and palaeoclimatological research	171:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	32	theme	useful	173:178	arg1	analyses					117:124	Hydrogen stable isotope analyses	93:124	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds	93:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	8	33	theme	different	1249:1257	arg1	compounds					1267:1275	different organic compounds	1249:1275	different organic compounds	1249:1275	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	1	34	theme	stable	102:107	arg1	tool					180:183	a useful tool	171:183	a useful tool for ecological, environmental, and palaeoclimatological research	171:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	34	theme	stable	102:107	arg1	δ2H					127:129	δ2H	127:129	δ2H	127:129	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	34	theme	stable	102:107	arg1	analyses					117:124	Hydrogen stable isotope analyses	93:124	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds	93:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	8	35	theme	specific	1391:1398	arg1	atoms					1402:1406	specific H atoms	1391:1406	specific H atoms	1391:1406	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	2	36	theme	changes	377:383	arg1	result					367:372	a result	365:372	a result of changes in plant carbon fluxes	365:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	2	37	from	result	367:372	arg1	fluxes					401:406	plant carbon fluxes	388:406	plant carbon fluxes	388:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	1	38	theme	isotope	109:115	arg1	tool					180:183	a useful tool	171:183	a useful tool for ecological, environmental, and palaeoclimatological research	171:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	38	theme	isotope	109:115	arg1	δ2H					127:129	δ2H	127:129	δ2H	127:129	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	1	38	theme	isotope	109:115	arg1	analyses					117:124	Hydrogen stable isotope analyses	93:124	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds	93:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	9	39	theme	cellulose	1486:1494	arg1	values					1511:1516	cellulose and phytol δ2H values	1486:1516	cellulose and phytol δ2H values	1486:1516	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	3	40	theme	plant	555:559	arg1	organs					561:566	plant organs	555:566	plant organs	555:566	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	5	41	theme	phytol	936:941	arg1	values					947:952	higher cellulose and phytol δ2H values	915:952	higher cellulose and phytol δ2H values	915:952	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	5	42	theme	δ2H	943:945	arg1	values					947:952	higher cellulose and phytol δ2H values	915:952	higher cellulose and phytol δ2H values	915:952	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	1	43	dep	derived	141:147	arg1	plant					135:139	plant	135:139	plant	135:139	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	9	44	theme	synthesis	1550:1558	arg1	effect					1524:1529	an effect	1521:1529	an effect of impaired starch synthesis	1521:1558	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	1	45	theme	ecological	189:198	arg1	research					241:248	ecological, environmental, and palaeoclimatological research	189:248	ecological, environmental, and palaeoclimatological research	189:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	0	46	theme	isotope	38:44	arg1	fractionation					46:58	hydrogen isotope fractionation	29:58	hydrogen isotope fractionation	29:58	The metabolic sensitivity of hydrogen isotope fractionation differs between plant compounds.					
36528118	4	47	theme	impaired	674:681	arg1	synthesis					690:698	impaired starch synthesis	674:698	impaired starch synthesis	674:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	4	48	theme	different	634:642	arg1	types					644:648	four different types	629:648	four different types of mutations that cause impaired starch synthesis	629:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	9	49	theme	phytol	1500:1505	arg1	values					1511:1516	cellulose and phytol δ2H values	1486:1516	cellulose and phytol δ2H values	1486:1516	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	0	50	theme	hydrogen	29:36	arg1	fractionation					46:58	hydrogen isotope fractionation	29:58	hydrogen isotope fractionation	29:58	The metabolic sensitivity of hydrogen isotope fractionation differs between plant compounds.					
36528118	1	51	link	derived	141:147	arg1	compounds					157:165	plant derived organic compounds	135:165	plant derived organic compounds	135:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	9	52	theme	δ2H	1507:1509	arg1	values					1511:1516	cellulose and phytol δ2H values	1486:1516	cellulose and phytol δ2H values	1486:1516	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	1	53	theme	environmental	201:213	arg1	research					241:248	ecological, environmental, and palaeoclimatological research	189:248	ecological, environmental, and palaeoclimatological research	189:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	9	54	theme	similar	1466:1472	arg1	increase					1474:1481	the similar increase	1462:1481	the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis	1462:1558	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	6	55	theme	lipid	1029:1033	arg1	biosynthesis					1035:1046	acetogenic lipid biosynthesis	1018:1046	acetogenic lipid biosynthesis	1018:1046	By contrast, 2H-fractionation during acetogenic lipid biosynthesis generally did not show strong metabolic sensitivity.					
36528118	8	56	theme	organic	1259:1265	arg1	compounds					1267:1275	different organic compounds	1249:1275	different organic compounds	1249:1275	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	2	57	from	changes	377:383	arg1	fluxes					401:406	plant carbon fluxes	388:406	plant carbon fluxes	388:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	4	58	theme	starch	683:688	arg1	synthesis					690:698	impaired starch synthesis	674:698	impaired starch synthesis	674:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	0	59	theme	fractionation	46:58	arg1	sensitivity					14:24	The metabolic sensitivity	0:24	The metabolic sensitivity of hydrogen isotope fractionation	0:58	The metabolic sensitivity of hydrogen isotope fractionation differs between plant compounds.					
36528118	5	60	with	mutants	865:871	arg1	synthesis					894:902	impaired starch synthesis	878:902	impaired starch synthesis	878:902	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	4	61	with	species	616:622	arg1	types					644:648	four different types	629:648	four different types of mutations that cause impaired starch synthesis	629:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	5	62	contain	had	911:913	arg2	values					947:952	higher cellulose and phytol δ2H values	915:952	higher cellulose and phytol δ2H values	915:952	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	5	62	contain	had	911:913	arg1	mutants					865:871	mutants	865:871	mutants with impaired starch synthesis	865:902	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	3	63	theme	plant	475:479	arg1	compounds					481:489	plant compounds	475:489	plant compounds	475:489	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	8	64	from	changes	1339:1345	arg1	C-metabolism					1350:1361	C-metabolism	1350:1361	C-metabolism	1350:1361	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	8	65	theme	H	1400:1400	arg1	atoms					1402:1406	specific H atoms	1391:1406	specific H atoms	1391:1406	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
36528118	3	66	theme	δ2H	459:461	arg1	patterns					463:470	the δ2H patterns	455:470	the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs	455:566	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	2	67	theme	biosynthetic	304:315	arg1	2H-fractionation					317:332	variable biosynthetic 2H-fractionation	295:332	variable biosynthetic 2H-fractionation	295:332	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	6	68	theme	acetogenic	1018:1027	arg1	biosynthesis					1035:1046	acetogenic lipid biosynthesis	1018:1046	acetogenic lipid biosynthesis	1018:1046	By contrast, 2H-fractionation during acetogenic lipid biosynthesis generally did not show strong metabolic sensitivity.					
36528118	5	69	theme	wild	970:973	arg1	type					975:978	the wild type	966:978	the wild type	966:978	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	4	70	theme	biosynthetic	763:774	arg1	2H-fractionation					776:791	the biosynthetic 2H-fractionation	759:791	the biosynthetic 2H-fractionation	759:791	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	9	71	from	increase	1474:1481	arg1	values					1511:1516	cellulose and phytol δ2H values	1486:1516	cellulose and phytol δ2H values	1486:1516	As such, we determined that the similar increase in cellulose and phytol δ2H values as an effect of impaired starch synthesis most likely originates in triose-phosphates.					
36528118	5	72	theme	cellulose	922:930	arg1	values					947:952	higher cellulose and phytol δ2H values	915:952	higher cellulose and phytol δ2H values	915:952	We found that mutants with impaired starch synthesis always had higher cellulose and phytol δ2H values compared to the wild type.					
36528118	4	73	theme	alternative	575:585	arg1	approach					587:594	an alternative approach	572:594	an alternative approach	572:594	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	0	74	theme	plant	76:80	arg1	compounds					82:90	plant compounds	76:90	plant compounds	76:90	The metabolic sensitivity of hydrogen isotope fractionation differs between plant compounds.					
36528118	4	75	theme	plant	610:614	arg1	species					616:622	four plant species	605:622	four plant species with four different types of mutations that cause impaired starch synthesis	605:698	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	2	76	from	fluxes	401:406	arg1	result					367:372	a result	365:372	a result of changes in plant carbon fluxes	365:406	However, during organic compound synthesis, variable biosynthetic 2H-fractionation has been suggested to occur as a result of changes in plant carbon fluxes.					
36528118	3	77	theme	environmental	497:509	arg1	gradients					511:519	environmental gradients	497:519	environmental gradients	497:519	So far, inference has been based on examining the δ2H patterns of plant compounds along environmental gradients, among plant species, and between plant organs.					
36528118	6	78	theme	strong	1071:1076	arg1	sensitivity					1088:1098	strong metabolic sensitivity	1071:1098	strong metabolic sensitivity	1071:1098	By contrast, 2H-fractionation during acetogenic lipid biosynthesis generally did not show strong metabolic sensitivity.					
36528118	1	79	theme	palaeoclimatological	220:239	arg1	research					241:248	ecological, environmental, and palaeoclimatological research	189:248	ecological, environmental, and palaeoclimatological research	189:248	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	7	80	theme	compound	1182:1189	arg1	pathway					1166:1172	the biosynthetic pathway	1149:1172	the biosynthetic pathway of each compound	1149:1189	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	7	80	theme	compound	1182:1189	arg1	source					1206:1211	the likely source	1195:1211	the likely source of the variable isotope effects	1195:1243	We rationalise these differences by considering the biosynthetic pathway of each compound and the likely source of the variable isotope effects.					
36528118	4	81	used	used	600:603	arg2	we					597:598	we	597:598	we	597:598	In an alternative approach, we used four plant species with four different types of mutations that cause impaired starch synthesis to assess whether variability in carbon metabolism affects the biosynthetic 2H-fractionation during cellulose, phytol, and acetogenic lipid synthesis.					
36528118	1	82	theme	derived	141:147	arg1	compounds					157:165	plant derived organic compounds	135:165	plant derived organic compounds	135:165	Hydrogen stable isotope analyses (δ2H) of plant derived organic compounds are a useful tool for ecological, environmental, and palaeoclimatological research.					
36528118	8	83	theme	variable	1297:1304	arg1	2H-fractionation					1319:1334	variable biosynthetic 2H-fractionation	1297:1334	variable biosynthetic 2H-fractionation	1297:1334	In different organic compounds, the sensitivity of variable biosynthetic 2H-fractionation to changes in C-metabolism depends on incorporation of specific H atoms from precursor molecules.					
37141966	7	0	theme	short-range	955:965	arg1	order					967:971	the short-range order	951:971	the short-range order of starch molecules more than the double helix structure	951:1028	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	2	1	contain	had	210:212	arg2	change					228:233	a significant change	214:233	a significant change in the b* value observed in the HS sample	214:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	2	1	contain	had	210:212	arg1	methods					202:208	Modification methods	189:208	Modification methods	189:208	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	8	2	located	observed	1085:1092	arg1	diffractogram					1105:1117	the XRD diffractogram	1097:1117	the XRD diffractogram	1097:1117	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	8	2	located	observed	1085:1092	arg2	reduction					1045:1053	A significant reduction	1031:1053	A significant reduction in relative crystallinity	1031:1079	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	8	3	theme	relative	1058:1065	arg1	crystallinity					1067:1079	relative crystallinity	1058:1079	relative crystallinity	1058:1079	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	1	4	theme	hydrothermal	143:154	arg1	methods					180:186	hydrothermal (HS) and microwave (MS) methods	143:186	hydrothermal (HS) and microwave (MS) methods	143:186	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	9	5	theme	HS	1246:1247	arg1	method					1269:1274	the HS and MS modification method	1242:1274	the HS and MS modification method	1242:1274	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	9	6	theme	food	1346:1349	arg1	applications					1351:1362	the food applications	1342:1362	the food applications of WFM starch	1342:1376	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	2	7	theme	*	243:243	arg1	value					245:249	the b* value	238:249	the b* value observed in the HS sample	238:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	4	8	theme	hydration	473:481	arg1	properties					483:492	The gel hydration properties	465:492	The gel hydration properties of modified starch	465:511	The gel hydration properties of modified starch enhanced significantly, especially in the HS sample.					
37141966	8	9	theme	granules	1208:1215	arg1	bonding					1190:1196	the hydrogen bonding	1177:1196	the hydrogen bonding of starch granules	1177:1215	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	9	10	theme	starch	1371:1376	arg1	applications					1351:1362	the food applications	1342:1362	the food applications of WFM starch	1342:1376	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	7	11	theme	molecules	983:991	arg1	order					967:971	the short-range order	951:971	the short-range order of starch molecules more than the double helix structure	951:1028	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	2	12	theme	b	242:242	arg1	value					245:249	the b* value	238:249	the b* value observed in the HS sample	238:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	4	13	theme	gel	469:471	arg1	properties					483:492	The gel hydration properties	465:492	The gel hydration properties of modified starch	465:511	The gel hydration properties of modified starch enhanced significantly, especially in the HS sample.					
37141966	6	14	dep	molecules	851:859	arg1	K					881:881	K	881:881	K	881:881	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	6	14	dep	molecules	851:859	arg1	index					874:878	consistency index	862:878	starch molecules' consistency index (K)	844:882	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	8	15	theme	XRD	1101:1103	arg1	diffractogram					1105:1117	the XRD diffractogram	1097:1117	the XRD diffractogram	1097:1117	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	9	16	theme	MS	1253:1254	arg1	method					1269:1274	the HS and MS modification method	1242:1274	the HS and MS modification method	1242:1274	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	5	17	theme	NS	696:697	arg1	got					699:701	the NS got	692:701	the NS got	692:701	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	5	18	theme	%	617:617	arg1	concentration					588:600	The least NS gelation concentration	566:600	The least NS gelation concentration (LGC) of 13.63 %	566:617	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	5	18	theme	%	617:617	arg1	LGC					603:605	LGC	603:605	LGC	603:605	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	6	19	theme	starch	844:849	arg1	molecules					851:859	starch molecules	844:859	starch molecules' consistency index (K)	844:882	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	6	20	theme	consistency	862:872	arg1	K					881:881	K	881:881	K	881:881	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	6	20	theme	consistency	862:872	arg1	index					874:878	consistency index	862:878	starch molecules' consistency index (K)	844:882	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	2	21	theme	∆C	311:312	arg1	value					315:319	the higher chroma (∆C) value	292:319	the higher chroma (∆C) value	292:319	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	0	22	theme	finger	6:11	arg1	starch					20:25	White finger millet starch	0:25	White finger millet starch: Hydrothermal and microwave modification and its characterisation.	0:92	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	8	23	from	reduction	1045:1053	arg1	crystallinity					1067:1079	relative crystallinity	1058:1079	relative crystallinity	1058:1079	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	8	24	from	change	1167:1172	arg1	bonding					1190:1196	the hydrogen bonding	1177:1196	the hydrogen bonding of starch granules	1177:1215	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	3	25	theme	pH	455:456	arg1	value					458:462	the pH value	451:462	the pH value	451:462	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	7	26	theme	double	1007:1012	arg1	structure					1020:1028	the double helix structure	1003:1028	the double helix structure	1003:1028	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	0	27	theme	White	0:4	arg1	starch					20:25	White finger millet starch	0:25	White finger millet starch: Hydrothermal and microwave modification and its characterisation.	0:92	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	6	28	theme	thinning	815:822	arg1	behavior					824:831	the shear thinning behavior	805:831	the shear thinning behavior	805:831	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	7	29	theme	modification	915:926	arg1	process					928:934	the modification process	911:934	the modification process	911:934	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	1	30	dep	hydrothermal	143:154	arg1	HS					157:158	HS	157:158	HS	157:158	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	2	31	theme	chroma	303:308	arg1	value					315:319	the higher chroma (∆C) value	292:319	the higher chroma (∆C) value	292:319	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	8	32	theme	significant	1033:1043	arg1	reduction					1045:1053	A significant reduction	1031:1053	A significant reduction in relative crystallinity	1031:1079	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	3	33	dep	composition	381:391	arg1	the					368:370	the	368:370	the	368:370	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	5	34	theme	gelation	579:586	arg1	concentration					588:600	The least NS gelation concentration	566:600	The least NS gelation concentration (LGC) of 13.63 %	566:617	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	5	34	theme	gelation	579:586	arg1	LGC					603:605	LGC	603:605	LGC	603:605	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	9	35	theme	modification	1256:1267	arg1	method					1269:1274	the HS and MS modification method	1242:1274	the HS and MS modification method	1242:1274	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	1	36	theme	finger	100:105	arg1	WFM					115:117	WFM	115:117	WFM	115:117	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	36	theme	finger	100:105	arg1	millet					107:112	White finger millet	94:112	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	37	theme	microwave	165:173	arg1	methods					180:186	hydrothermal (HS) and microwave (MS) methods	143:186	hydrothermal (HS) and microwave (MS) methods	143:186	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	38	theme	White	94:98	arg1	WFM					115:117	WFM	115:117	WFM	115:117	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	38	theme	White	94:98	arg1	millet					107:112	White finger millet	94:112	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	39	theme	millet	107:112	arg1	starch					120:125	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	2	40	from	change	228:233	arg1	value					245:249	the b* value	238:249	the b* value observed in the HS sample	238:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	3	41	theme	native	420:425	arg1	starch					427:432	native starch	420:432	native starch	420:432	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	0	42	theme	Hydrothermal	28:39	arg1	modification					55:66	Hydrothermal and microwave modification	28:66	Hydrothermal and microwave modification	28:66	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	2	43	located	observed	251:258	arg1	sample					270:275	the HS sample	263:275	the HS sample	263:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	2	43	located	observed	251:258	arg2	value					245:249	the b* value	238:249	the b* value observed in the HS sample	238:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	7	44	theme	FTIR	885:888	arg1	results					890:896	FTIR results	885:896	FTIR results	885:896	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	7	45	theme	helix	1014:1018	arg1	structure					1020:1028	the double helix structure	1003:1028	the double helix structure	1003:1028	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	8	46	theme	significant	1155:1165	arg1	change					1167:1172	the significant change	1151:1172	the significant change in the hydrogen bonding of starch granules	1151:1215	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	4	47	theme	HS	555:556	arg1	sample					558:563	the HS sample	551:563	the HS sample	551:563	The gel hydration properties of modified starch enhanced significantly, especially in the HS sample.					
37141966	1	48	mod	modified	131:138	arg3	methods					180:186	hydrothermal (HS) and microwave (MS) methods	143:186	hydrothermal (HS) and microwave (MS) methods	143:186	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	1	48	mod	modified	131:138	arg1	starch					120:125	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch	94:125	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	7	49	theme	more	993:996	arg1	order					967:971	the short-range order	951:971	the short-range order of starch molecules more than the double helix structure	951:1028	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	2	50	theme	Modification	189:200	arg1	methods					202:208	Modification methods	189:208	Modification methods	189:208	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	3	51	theme	chemical	372:379	arg1	composition					381:391	chemical composition	372:391	chemical composition	372:391	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	0	52	theme	microwave	45:53	arg1	modification					55:66	Hydrothermal and microwave modification	28:66	Hydrothermal and microwave modification	28:66	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	6	53	theme	starch	782:787	arg1	samples					789:795	The starch samples	778:795	The starch samples	778:795	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	8	54	theme	hydrogen	1181:1188	arg1	bonding					1190:1196	the hydrogen bonding	1177:1196	the hydrogen bonding of starch granules	1177:1215	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	6	55	theme	shear	809:813	arg1	behavior					824:831	the shear thinning behavior	805:831	the shear thinning behavior	805:831	The starch samples exhibit the shear thinning behavior and reduce starch molecules' consistency index (K).					
37141966	8	56	theme	starch	1201:1206	arg1	granules					1208:1215	starch granules	1201:1215	starch granules	1201:1215	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	8	57	theme	DSC	1128:1130	arg1	thermogram					1132:1141	the DSC thermogram	1124:1141	the DSC thermogram	1124:1141	A significant reduction in relative crystallinity was observed in the XRD diffractogram, and the DSC thermogram depicts the significant change in the hydrogen bonding of starch granules.					
37141966	7	58	theme	starch	976:981	arg1	molecules					983:991	starch molecules	976:991	starch molecules	976:991	FTIR results exhibit that the modification process highly altered the short-range order of starch molecules more than the double helix structure.					
37141966	9	59	theme	WFM	1367:1369	arg1	starch					1371:1376	WFM starch	1367:1376	WFM starch	1367:1376	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	3	60	dep	changed	360:366	arg1	NS					435:436	NS	435:436	NS	435:436	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	0	61	dep	starch	20:25	arg1	modification					55:66	Hydrothermal and microwave modification	28:66	Hydrothermal and microwave modification	28:66	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	0	61	dep	starch	20:25	arg1	characterisation					76:91	its characterisation	72:91	its characterisation	72:91	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	3	62	theme	water	397:401	arg1	aw					413:414	aw	413:414	aw	413:414	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	3	62	theme	water	397:401	arg1	activity					403:410	water activity	397:410	water activity (aw)	397:415	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	5	63	theme	NS	576:577	arg1	concentration					588:600	The least NS gelation concentration	566:600	The least NS gelation concentration (LGC) of 13.63 %	566:617	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	5	63	theme	NS	576:577	arg1	LGC					603:605	LGC	603:605	LGC	603:605	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	2	64	theme	significant	216:226	arg1	change					228:233	a significant change	214:233	a significant change in the b* value observed in the HS sample	214:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	2	65	theme	HS	267:268	arg1	sample					270:275	the HS sample	263:275	the HS sample	263:275	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	5	66	theme	setback	759:765	arg1	viscosity					767:775	the setback viscosity	755:775	the setback viscosity	755:775	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	9	67	theme	starch	1315:1320	arg1	properties					1301:1310	the properties	1297:1310	the properties	1297:1310	It can be inferred that the HS and MS modification method significantly alters the properties of starch, which can increase the food applications of WFM starch.					
37141966	5	68	theme	modification	722:733	arg1	process					735:741	the modification process	718:741	the modification process	718:741	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	1	69	dep	microwave	165:173	arg1	MS					176:177	MS	176:177	MS	176:177	White finger millet (WFM) starch was modified by hydrothermal (HS) and microwave (MS) methods.					
37141966	5	70	theme	pasting	669:675	arg1	temperature					677:687	The pasting temperature	665:687	The pasting temperature of the NS got	665:701	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	2	71	theme	higher	296:301	arg1	value					315:319	the higher chroma (∆C) value	292:319	the higher chroma (∆C) value	292:319	Modification methods had a significant change in the b* value observed in the HS sample, and it caused the higher chroma (∆C) value.					
37141966	5	72	theme	got	699:701	arg1	temperature					677:687	The pasting temperature	665:687	The pasting temperature of the NS got	665:701	The least NS gelation concentration (LGC) of 13.63 % increased to 17.74 % in HS and 16.41 % in MS. The pasting temperature of the NS got reduced during the modification process and altered the setback viscosity.					
37141966	4	73	theme	starch	506:511	arg1	properties					483:492	The gel hydration properties	465:492	The gel hydration properties of modified starch	465:511	The gel hydration properties of modified starch enhanced significantly, especially in the HS sample.					
37141966	0	74	theme	millet	13:18	arg1	starch					20:25	White finger millet starch	0:25	White finger millet starch: Hydrothermal and microwave modification and its characterisation.	0:92	White finger millet starch: Hydrothermal and microwave modification and its characterisation.					
37141966	3	75	theme	starch	427:432	arg1	aw					413:414	aw	413:414	aw	413:414	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	3	75	theme	starch	427:432	arg1	composition					381:391	chemical composition	372:391	chemical composition	372:391	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	3	75	theme	starch	427:432	arg1	activity					403:410	water activity	397:410	water activity (aw)	397:415	The treatments have not significantly changed the chemical composition and water activity (aw) of native starch (NS) but reduced the pH value.					
37141966	4	76	theme	modified	497:504	arg1	starch					506:511	modified starch	497:511	modified starch	497:511	The gel hydration properties of modified starch enhanced significantly, especially in the HS sample.					
36619858	8	0	theme	unique	1077:1082	arg1	contributions					1098:1110	additive genetic, shared, and unique environmental contributions	1047:1110	additive genetic, shared, and unique environmental contributions	1047:1110	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	4	1	theme	simple	538:543	arg1	interventions					555:567	simple lifestyle interventions	538:567	simple lifestyle interventions	538:567	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	6	2	theme	environmental	761:773	arg1	factors					775:781	genetic and environmental factors	749:781	genetic and environmental factors	749:781	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	12	3	theme	environmental	1711:1723	arg1	factors					1725:1731	shared environmental factors	1704:1731	shared environmental factors (C)	1704:1735	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	3	theme	environmental	1711:1723	arg1	C					1734:1734	C	1734:1734	C	1734:1734	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	6	4	theme	genetic	749:755	arg1	factors					775:781	genetic and environmental factors	749:781	genetic and environmental factors	749:781	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	11	5	theme	study	1595:1599	arg1	points					1568:1573	all time points	1559:1573	all time points of the longitudinal study	1559:1599	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	2	6	theme	predictive	265:274	arg1	pattern					276:282	a predictive pattern	263:282	a predictive pattern	263:282	IgG glycome composition changes with age and health in a predictive pattern, presumably due to inflammaging.					
36619858	8	7	theme	twin	1125:1128	arg1	design					1130:1135	a classical twin design	1113:1135	a classical twin design	1113:1135	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	7	8	from	pairs	942:946	arg1	glycans					898:904	IgG glycans	894:904	IgG glycans from monozygotic and dizygotic twin pairs	894:946	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	8	9	dep	genetic	1056:1062	arg1	environmental					1084:1096	environmental	1084:1096	environmental	1084:1096	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	5	10	theme	studies	600:606	arg1	none					579:582	none	579:582	none of the previous studies	579:606	However, none of the previous studies determined to which extent the glycan clock can be turned, and how much is fixed by genetic predisposition.					
36619858	13	11	theme	%	1870:1870	arg1	average					1857:1863	an average	1854:1863	an average of 71%	1854:1870	Interestingly, heritability estimates nearly doubled, to an average of 71%, when we included age as a covariant.					
36619858	1	12	theme	multiple	191:198	arg1	levels					200:205	multiple levels	191:205	multiple levels	191:205	Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels.					
36619858	15	13	dep	defines	2090:2096	arg1	dictates					2160:2167	dictates	2160:2167	dictates the glycan clock's ticking	2160:2194	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	9	14	theme	clock	1177:1181	arg1	Heritability					1150:1161	Heritability	1150:1161	Heritability of the glycan clock	1150:1181	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	5	15	theme	glycan	639:644	arg1	clock					646:650	the glycan clock	635:650	the glycan clock	635:650	However, none of the previous studies determined to which extent the glycan clock can be turned, and how much is fixed by genetic predisposition.					
36619858	6	16	theme	female	878:883	arg1	cohorts					885:891	two TwinsUK female cohorts	866:891	two TwinsUK female cohorts	866:891	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	1	17	theme	N-glycans	128:136	arg1	addition					108:115	the addition	104:115	the addition of complex N-glycans	104:136	Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels.					
36619858	12	18	theme	environmental	1666:1678	arg1	contributions					1680:1692	Most environmental contributions	1661:1692	Most environmental contributions	1661:1692	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	4	19	theme	Glycan	402:407	arg1	first					429:433	first	429:433	first	429:433	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	4	19	theme	Glycan	402:407	arg1	clock					409:413	Glycan clock	402:413	Glycan clock of age	402:420	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	5	20	theme	genetic	692:698	arg1	predisposition					700:713	genetic predisposition	692:713	genetic predisposition	692:713	However, none of the previous studies determined to which extent the glycan clock can be turned, and how much is fixed by genetic predisposition.					
36619858	7	21	theme	dizygotic	927:935	arg1	pairs					942:946	monozygotic and dizygotic twin pairs	911:946	monozygotic and dizygotic twin pairs	911:946	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	4	22	theme	clocks	455:460	arg1	first					429:433	first	429:433	first	429:433	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	4	22	theme	clocks	455:460	arg1	clock					409:413	Glycan clock	402:413	Glycan clock of age	402:420	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	7	23	theme	monozygotic	911:921	arg1	pairs					942:946	monozygotic and dizygotic twin pairs	911:946	monozygotic and dizygotic twin pairs	911:946	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	16	24	theme	biomarkers	2412:2421	arg1	biomarkers					2412:2421	the most potent biomarkers	2396:2421	the most potent biomarkers of biological aging	2396:2441	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	16	24	theme	biomarkers	2412:2421	arg1	one					2389:2391	one	2389:2391	one	2389:2391	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	3	25	theme	biological	338:347	arg1	result					322:327	a result	320:327	a result	320:327	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	25	theme	biological	338:347	arg1	biomarker					355:363	a novel biological aging biomarker	330:363	a novel biological aging biomarker	330:363	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	25	theme	biological	338:347	arg1	clock					373:377	glycan clock	366:377	glycan clock of age	366:384	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	9	26	theme	longitudinal	1246:1257	arg1	participants					1202:1213	participants	1202:1213	participants of one cross-sectional and one longitudinal cohort with three time points	1202:1287	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	1	27	theme	Immunoglobulin	52:65	arg1	G					67:67	Immunoglobulin G	52:67	Immunoglobulin G	52:67	Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels.					
36619858	10	28	theme	moderate	1408:1415	arg1	contribution					1417:1428	a moderate contribution	1406:1428	a moderate contribution of additive genetic factors (A) to glycan clock variation	1406:1486	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	3	29	theme	glycan	366:371	arg1	biomarker					355:363	a novel biological aging biomarker	330:363	a novel biological aging biomarker	330:363	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	29	theme	glycan	366:371	arg1	clock					373:377	glycan clock	366:377	glycan clock of age	366:384	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	4	30	theme	biological	438:447	arg1	clocks					455:460	biological aging clocks	438:460	biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions	438:567	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	14	31	theme	clock	2011:2015	arg1	variation					2017:2025	glycan clock variation	2004:2025	glycan clock variation	2004:2025	This intervention also inflated the estimates of unique environmental factors contributing to glycan clock variation.					
36619858	9	32	theme	time	1277:1280	arg1	points					1282:1287	three time points	1271:1287	three time points	1271:1287	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	16	33	theme	potent	2405:2410	arg1	biomarkers					2412:2421	the most potent biomarkers	2396:2421	the most potent biomarkers of biological aging	2396:2441	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	10	34	theme	genetic	1442:1448	arg1	A					1459:1459	A	1459:1459	A	1459:1459	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	10	34	theme	genetic	1442:1448	arg1	factors					1450:1456	additive genetic factors	1433:1456	additive genetic factors (A)	1433:1460	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	6	35	theme	clock	821:825	arg1	variation					797:805	phenotypic variation	786:805	phenotypic variation of the glycan clock	786:825	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	4	36	theme	reversal	519:526	arg1	possibility					498:508	a possibility	496:508	a possibility of clock reversal	496:526	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	14	37	theme	factors	1980:1986	arg1	estimates					1946:1954	the estimates	1942:1954	the estimates of unique environmental factors contributing to glycan clock variation	1942:2025	This intervention also inflated the estimates of unique environmental factors contributing to glycan clock variation.					
36619858	0	38	theme	clock	27:31	arg1	Heritability					0:11	Heritability	0:11	Heritability of the glycan clock of biological age	0:49	Heritability of the glycan clock of biological age.					
36619858	9	39	dep	cross-sectional	1222:1236	arg1	cohort					1259:1264	cohort	1259:1264	cohort	1259:1264	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	16	40	theme	biological	2426:2435	arg1	aging					2437:2441	biological aging	2426:2441	biological aging	2426:2441	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	14	41	theme	unique	1959:1964	arg1	factors					1980:1986	unique environmental factors	1959:1986	unique environmental factors contributing to glycan clock variation	1959:2025	This intervention also inflated the estimates of unique environmental factors contributing to glycan clock variation.					
36619858	11	42	theme	glycome	1618:1624	arg1	composition					1626:1636	IgG glycome composition	1614:1636	IgG glycome composition	1614:1636	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	0	43	theme	biological	36:45	arg1	age					47:49	biological age	36:49	biological age	36:49	Heritability of the glycan clock of biological age.					
36619858	15	44	theme	complex	2030:2036	arg1	interplay					2038:2046	A complex interplay	2028:2046	A complex interplay between genetic and environmental factors	2028:2088	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	2	45	theme	IgG	208:210	arg1	composition					220:230	IgG glycome composition	208:230	IgG glycome composition	208:230	IgG glycome composition changes with age and health in a predictive pattern, presumably due to inflammaging.					
36619858	8	46	theme	genetic	1056:1062	arg1	contributions					1098:1110	additive genetic, shared, and unique environmental contributions	1047:1110	additive genetic, shared, and unique environmental contributions	1047:1110	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	11	47	theme	time	1563:1566	arg1	points					1568:1573	all time points	1559:1573	all time points of the longitudinal study	1559:1599	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	8	48	theme	shared	1065:1070	arg1	contributions					1098:1110	additive genetic, shared, and unique environmental contributions	1047:1110	additive genetic, shared, and unique environmental contributions	1047:1110	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	6	49	theme	TwinsUK	870:876	arg1	cohorts					885:891	two TwinsUK female cohorts	866:891	two TwinsUK female cohorts	866:891	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	12	50	theme	unique	1743:1748	arg1	factors					1764:1770	unique environmental factors	1743:1770	unique environmental factors (E) having a minor role	1743:1794	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	50	theme	unique	1743:1748	arg1	E					1773:1773	E	1773:1773	E	1773:1773	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	10	51	theme	glycan	1465:1470	arg1	variation					1478:1486	glycan clock variation	1465:1486	glycan clock variation	1465:1486	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	11	52	theme	longitudinal	1582:1593	arg1	study					1595:1599	the longitudinal study	1578:1599	the longitudinal study	1578:1599	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	16	53	theme	biological	2289:2298	arg1	age					2300:2302	the biological age	2285:2302	the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging	2285:2441	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	16	54	theme	strong	2268:2273	arg1	impact					2275:2280	a strong impact	2266:2280	a strong impact	2266:2280	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	16	55	dep	factors	2223:2229	arg1	including					2232:2240	including	2232:2240	including lifestyle choices	2232:2258	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	6	56	theme	heritability	841:852	arg1	analysis					854:861	heritability analysis	841:861	heritability analysis	841:861	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	4	57	theme	lifestyle	545:553	arg1	interventions					555:567	simple lifestyle interventions	538:567	simple lifestyle interventions	538:567	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	15	58	theme	IgG	2110:2112	arg1	glycosylation					2114:2126	alternative IgG glycosylation	2098:2126	alternative IgG glycosylation	2098:2126	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	5	59	theme	previous	591:598	arg1	studies					600:606	the previous studies	587:606	the previous studies	587:606	However, none of the previous studies determined to which extent the glycan clock can be turned, and how much is fixed by genetic predisposition.					
36619858	11	60	theme	heritability	1501:1512	arg1	estimates					1514:1522	heritability estimates	1501:1522	heritability estimates	1501:1522	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	8	61	theme	classical	1115:1123	arg1	design					1130:1135	a classical twin design	1113:1135	a classical twin design	1113:1135	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	10	62	from	%	1381:1381	arg1	average					1386:1392	average	1386:1392	average	1386:1392	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	12	63	theme	shared	1704:1709	arg1	factors					1725:1731	shared environmental factors	1704:1731	shared environmental factors (C)	1704:1735	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	63	theme	shared	1704:1709	arg1	C					1734:1734	C	1734:1734	C	1734:1734	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	10	64	theme	glycan	1362:1367	arg1	clock					1369:1373	the glycan clock	1358:1373	the glycan clock	1358:1373	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	10	64	theme	glycan	1362:1367	arg1	%					1381:1381	39%	1379:1381	39%	1379:1381	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	7	65	theme	glycan	1011:1016	arg1	clock					1018:1022	the glycan clock	1007:1022	the glycan clock	1007:1022	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	15	66	theme	environmental	2068:2080	arg1	factors					2082:2088	genetic and environmental factors	2056:2088	genetic and environmental factors	2056:2088	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	4	67	theme	age	418:420	arg1	first					429:433	first	429:433	first	429:433	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	4	67	theme	age	418:420	arg1	clock					409:413	Glycan clock	402:413	Glycan clock of age	402:420	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	9	68	theme	glycan	1170:1175	arg1	clock					1177:1181	the glycan clock	1166:1181	the glycan clock	1166:1181	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	15	69	theme	alternative	2098:2108	arg1	glycosylation					2114:2126	alternative IgG glycosylation	2098:2126	alternative IgG glycosylation	2098:2126	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	15	70	theme	genetic	2056:2062	arg1	factors					2082:2088	genetic and environmental factors	2056:2088	genetic and environmental factors	2056:2088	A complex interplay between genetic and environmental factors defines alternative IgG glycosylation during aging and, consequently, dictates the glycan clock's ticking.					
36619858	16	71	theme	aging	2437:2441	arg1	biomarkers					2412:2421	the most potent biomarkers	2396:2421	the most potent biomarkers of biological aging	2396:2441	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	7	72	theme	glycan	975:980	arg1	age					982:984	glycan age	975:984	glycan age	975:984	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	1	73	theme	complex	120:126	arg1	N-glycans					128:136	complex N-glycans	120:136	complex N-glycans	120:136	Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels.					
36619858	16	74	theme	lifestyle	2242:2250	arg1	choices					2252:2258	lifestyle choices	2242:2258	lifestyle choices	2242:2258	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	12	75	theme	Most	1661:1664	arg1	contributions					1680:1692	Most environmental contributions	1661:1692	Most environmental contributions	1661:1692	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	13	76	theme	heritability	1812:1823	arg1	estimates					1825:1833	heritability estimates	1812:1833	heritability estimates	1812:1833	Interestingly, heritability estimates nearly doubled, to an average of 71%, when we included age as a covariant.					
36619858	9	77	theme	cross-sectional	1222:1236	arg1	participants					1202:1213	participants	1202:1213	participants of one cross-sectional and one longitudinal cohort with three time points	1202:1287	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	16	78	contain	have	2261:2264	arg1	factors					2223:2229	environmental factors	2209:2229	environmental factors (including lifestyle choices)	2209:2259	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	16	78	contain	have	2261:2264	arg2	impact					2275:2280	a strong impact	2266:2280	a strong impact	2266:2280	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	7	79	theme	twin	937:940	arg1	pairs					942:946	monozygotic and dizygotic twin pairs	911:946	monozygotic and dizygotic twin pairs	911:946	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	5	80	dep	turned	659:664	arg1	fixed					683:687	fixed	683:687	fixed	683:687	However, none of the previous studies determined to which extent the glycan clock can be turned, and how much is fixed by genetic predisposition.					
36619858	4	81	theme	multiple	472:479	arg1	studies					481:487	multiple studies	472:487	multiple studies	472:487	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	3	82	theme	aging	349:353	arg1	result					322:327	a result	320:327	a result	320:327	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	82	theme	aging	349:353	arg1	biomarker					355:363	a novel biological aging biomarker	330:363	a novel biological aging biomarker	330:363	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	82	theme	aging	349:353	arg1	clock					373:377	glycan clock	366:377	glycan clock of age	366:384	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	9	83	with	participants	1202:1213	arg1	points					1282:1287	three time points	1271:1287	three time points	1271:1287	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	3	84	theme	novel	332:336	arg1	result					322:327	a result	320:327	a result	320:327	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	84	theme	novel	332:336	arg1	biomarker					355:363	a novel biological aging biomarker	330:363	a novel biological aging biomarker	330:363	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	84	theme	novel	332:336	arg1	clock					373:377	glycan clock	366:377	glycan clock of age	366:384	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	4	85	theme	aging	449:453	arg1	clocks					455:460	biological aging clocks	438:460	biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions	438:567	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	7	86	theme	IgG	894:896	arg1	glycans					898:904	IgG glycans	894:904	IgG glycans from monozygotic and dizygotic twin pairs	894:946	IgG glycans from monozygotic and dizygotic twin pairs were analyzed by UHPLC and glycan age was calculated using the glycan clock.					
36619858	4	87	theme	clock	513:517	arg1	reversal					519:526	clock reversal	513:526	clock reversal	513:526	Glycan clock of age is the first of biological aging clocks for which multiple studies showed a possibility of clock reversal even with simple lifestyle interventions.					
36619858	14	88	theme	glycan	2004:2009	arg1	variation					2017:2025	glycan clock variation	2004:2025	glycan clock variation	2004:2025	This intervention also inflated the estimates of unique environmental factors contributing to glycan clock variation.					
36619858	0	89	theme	glycan	20:25	arg1	clock					27:31	the glycan clock	16:31	the glycan clock of biological age	16:49	Heritability of the glycan clock of biological age.					
36619858	10	90	theme	additive	1433:1440	arg1	A					1459:1459	A	1459:1459	A	1459:1459	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	10	90	theme	additive	1433:1440	arg1	factors					1450:1456	additive genetic factors	1433:1456	additive genetic factors (A)	1433:1460	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	16	91	theme	environmental	2209:2221	arg1	factors					2223:2229	environmental factors	2209:2229	environmental factors (including lifestyle choices)	2209:2259	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	6	92	theme	glycan	814:819	arg1	clock					821:825	the glycan clock	810:825	the glycan clock	810:825	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	14	93	theme	environmental	1966:1978	arg1	factors					1980:1986	unique environmental factors	1959:1986	unique environmental factors contributing to glycan clock variation	1959:2025	This intervention also inflated the estimates of unique environmental factors contributing to glycan clock variation.					
36619858	11	94	theme	IgG	1614:1616	arg1	composition					1626:1636	IgG glycome composition	1614:1636	IgG glycome composition	1614:1636	Remarkably, heritability estimates remained approximately the same in all time points of the longitudinal study, even though IgG glycome composition changed substantially.					
36619858	16	95	theme	glycan	2322:2327	arg1	clock					2329:2333	the glycan clock	2318:2333	the glycan clock	2318:2333	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	0	96	theme	age	47:49	arg1	clock					27:31	the glycan clock	16:31	the glycan clock of biological age	16:49	Heritability of the glycan clock of biological age.					
36619858	8	97	theme	additive	1047:1054	arg1	contributions					1098:1110	additive genetic, shared, and unique environmental contributions	1047:1110	additive genetic, shared, and unique environmental contributions	1047:1110	In order to determine additive genetic, shared, and unique environmental contributions, a classical twin design was applied.					
36619858	12	98	theme	environmental	1750:1762	arg1	factors					1764:1770	unique environmental factors	1743:1770	unique environmental factors (E) having a minor role	1743:1794	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	98	theme	environmental	1750:1762	arg1	E					1773:1773	E	1773:1773	E	1773:1773	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	3	99	theme	age	382:384	arg1	biomarker					355:363	a novel biological aging biomarker	330:363	a novel biological aging biomarker	330:363	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	3	99	theme	age	382:384	arg1	clock					373:377	glycan clock	366:377	glycan clock of age	366:384	As a result, a novel biological aging biomarker, glycan clock of age, was developed.					
36619858	16	100	theme	aging	2374:2378	arg1	clock					2380:2384	this aging clock	2369:2384	this aging clock	2369:2384	Apparently, environmental factors (including lifestyle choices) have a strong impact on the biological age measured with the glycan clock, which additionally clarifies why this aging clock is one of the most potent biomarkers of biological aging.					
36619858	2	101	theme	glycome	212:218	arg1	composition					220:230	IgG glycome composition	208:230	IgG glycome composition	208:230	IgG glycome composition changes with age and health in a predictive pattern, presumably due to inflammaging.					
36619858	9	102	theme	measurements	1318:1329	arg1	reliability					1303:1313	the reliability	1299:1313	the reliability of measurements	1299:1329	Heritability of the glycan clock was calculated for participants of one cross-sectional and one longitudinal cohort with three time points to assess the reliability of measurements.					
36619858	12	103	theme	minor	1785:1789	arg1	role					1791:1794	a minor role	1783:1794	a minor role	1783:1794	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	6	104	theme	phenotypic	786:795	arg1	variation					797:805	phenotypic variation	786:805	phenotypic variation of the glycan clock	786:825	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	10	105	theme	factors	1450:1456	arg1	contribution					1417:1428	a moderate contribution	1406:1428	a moderate contribution of additive genetic factors (A) to glycan clock variation	1406:1486	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36619858	12	106	contain	having	1776:1781	arg1	factors					1764:1770	unique environmental factors	1743:1770	unique environmental factors (E) having a minor role	1743:1794	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	106	contain	having	1776:1781	arg2	role					1791:1794	a minor role	1783:1794	a minor role	1783:1794	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	12	106	contain	having	1776:1781	arg1	E					1773:1773	E	1773:1773	E	1773:1773	Most environmental contributions came from shared environmental factors (C), with unique environmental factors (E) having a minor role.					
36619858	6	107	theme	factors	775:781	arg1	contribution					733:744	the contribution	729:744	the contribution of genetic and environmental factors to phenotypic variation of the glycan clock	729:825	To determine the contribution of genetic and environmental factors to phenotypic variation of the glycan clock, we performed heritability analysis on two TwinsUK female cohorts.					
36619858	10	108	theme	clock	1472:1476	arg1	variation					1478:1486	glycan clock variation	1465:1486	glycan clock variation	1465:1486	Heritability estimate for the glycan clock was 39% on average, suggesting a moderate contribution of additive genetic factors (A) to glycan clock variation.					
36951486	5	0	theme	factory	1211:1217	arg1	productivity					1186:1197	the productivity	1182:1197	the productivity of the cell factory	1182:1217	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	1	1	theme	synthetic	158:166	arg1	receptors					168:176	abiotic synthetic receptors	150:176	abiotic synthetic receptors designed to feature selective bacterial recognition properties	150:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	5	2	theme	molecules	1148:1156	arg1	expression					1101:1110	the expression	1097:1110	the expression of quorum-sensing-controlled signal molecules	1097:1156	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	2	3	theme	marker	508:513	arg1	LPS					535:537	LPS	535:537	LPS	535:537	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	2	3	theme	marker	508:513	arg1	lipopolysaccharide					515:532	the surface marker lipopolysaccharide	496:532	the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	496:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	1	4	theme	receptors	168:176	arg1	preparation					135:145	the preparation	131:145	the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties	131:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	2	5	theme	bacteria	557:564	arg1	LPS					535:537	LPS	535:537	LPS	535:537	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	2	5	theme	bacteria	557:564	arg1	lipopolysaccharide					515:532	the surface marker lipopolysaccharide	496:532	the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	496:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	3	6	theme	resulting	571:579	arg1	nanoparticles					595:607	The resulting LPS-imprinted nanoparticles	567:607	The resulting LPS-imprinted nanoparticles	567:607	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	1	7	theme	environmental	280:292	arg1	adaptability					294:305	environmental adaptability	280:305	environmental adaptability	280:305	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	2	8	theme	Gram-negative	543:555	arg1	bacteria					557:564	Gram-negative bacteria	543:564	Gram-negative bacteria	543:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	4	9	theme	photothermal	942:953	arg1	treatment					955:963	photothermal treatment	942:963	photothermal treatment	942:963	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	3	10	theme	LPS-imprinted	581:593	arg1	nanoparticles					595:607	The resulting LPS-imprinted nanoparticles	567:607	The resulting LPS-imprinted nanoparticles	567:607	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	3	11	theme	whole	778:782	arg1	blood					784:788	whole blood	778:788	whole blood	778:788	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	4	12	theme	selective	900:908	arg1	inactivation					920:931	selective microbial inactivation	900:931	selective microbial inactivation based on photothermal treatment	900:963	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	1	13	theme	feature	190:196	arg1	properties					230:239	feature selective bacterial recognition properties	190:239	feature selective bacterial recognition properties	190:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	3	14	theme	specific	757:764	arg1	bacteria					766:773	specific bacteria	757:773	specific bacteria in whole blood	757:788	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	2	15	theme	surface	500:506	arg1	LPS					535:537	LPS	535:537	LPS	535:537	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	2	15	theme	surface	500:506	arg1	lipopolysaccharide					515:532	the surface marker lipopolysaccharide	496:532	the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	496:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	2	16	theme	synthetic	462:470	arg1	receptors					472:480	abiotic synthetic receptors	454:480	abiotic synthetic receptors	454:480	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	0	17	theme	Bacterial	75:83	arg1	Recognition					85:95	Selective Bacterial Recognition	65:95	Selective Bacterial Recognition	65:95	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	3	18	theme	remarkable	616:625	arg1	affinity					627:634	remarkable affinity	616:634	remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M	616:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	2	19	theme	polymer	399:405	arg1	formulation					407:417	the optimal polymer formulation	387:417	the optimal polymer formulation on 96-well plates	387:435	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	0	20	theme	Rapid	0:4	arg1	Screening					6:14	Screening	6:14	Screening	6:14	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	4	21	theme	microbial	910:918	arg1	inactivation					920:931	selective microbial inactivation	900:931	selective microbial inactivation based on photothermal treatment	900:963	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	1	22	theme	selective	198:206	arg1	properties					230:239	feature selective bacterial recognition properties	190:239	feature selective bacterial recognition properties	190:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	2	23	theme	abiotic	454:460	arg1	receptors					472:480	abiotic synthetic receptors	454:480	abiotic synthetic receptors	454:480	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	1	24	theme	live	310:313	arg1	microbes					315:322	live microbes	310:322	live microbes	310:322	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	4	25	theme	gold	850:853	arg1	nanorods					855:862	gold nanorods	850:862	gold nanorods	850:862	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	5	26	theme	quorum-sensing-controlled	1115:1139	arg1	molecules					1148:1156	quorum-sensing-controlled signal molecules	1115:1156	quorum-sensing-controlled signal molecules	1115:1156	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	1	27	theme	major	102:106	arg1	complexity					249:258	the complexity	245:258	the complexity	245:258	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	27	theme	major	102:106	arg1	challenges					108:117	The major challenges	98:117	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties	98:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	28	theme	bacterial	208:216	arg1	properties					230:239	feature selective bacterial recognition properties	190:239	feature selective bacterial recognition properties	190:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	3	29	with	affinity	627:634	arg1	value					694:698	an equilibrium dissociation constant (KD) value	652:698	an equilibrium dissociation constant (KD) value of 10-12 M	652:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	1	30	theme	microbes	315:322	arg1	challenges					108:117	The major challenges	98:117	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties	98:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	30	theme	microbes	315:322	arg1	nonrobustness					261:273	nonrobustness	261:273	nonrobustness	261:273	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	30	theme	microbes	315:322	arg1	complexity					249:258	the complexity	245:258	the complexity	245:258	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	30	theme	microbes	315:322	arg1	adaptability					294:305	environmental adaptability	280:305	environmental adaptability	280:305	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	1	31	theme	recognition	218:228	arg1	properties					230:239	feature selective bacterial recognition properties	190:239	feature selective bacterial recognition properties	190:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
36951486	0	32	theme	Abiotic	33:39	arg1	Receptors					51:59	Abiotic Synthetic Receptors	33:59	Abiotic Synthetic Receptors	33:59	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	2	33	theme	optimal	391:397	arg1	formulation					407:417	the optimal polymer formulation	387:417	the optimal polymer formulation on 96-well plates	387:435	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	5	34	with	nanoparticles	1011:1023	arg1	affinity					1035:1042	high affinity	1030:1042	high affinity for bacteria	1030:1055	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	4	35	theme	nanorods	855:862	arg1	incorporation					833:845	The incorporation	829:845	The incorporation of gold nanorods into imprinted nanoparticles	829:891	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	2	36	theme	96-well	422:428	arg1	plates					430:435	96-well plates	422:435	96-well plates	422:435	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	0	37	theme	Receptors	51:59	arg1	Synthesis					20:28	Synthesis	20:28	Synthesis	20:28	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	0	37	theme	Receptors	51:59	arg1	Screening					6:14	Screening	6:14	Screening	6:14	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	3	38	theme	down	808:811	arg1	concentrations					793:806	concentrations	793:806	concentrations down to 10 cells/mL	793:826	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	5	39	theme	cell	1206:1209	arg1	factory					1211:1217	the cell factory	1202:1217	the cell factory	1202:1217	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	2	40	theme	screening	355:363	arg1	strategy					365:372	a new rapid screening strategy	343:372	a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	343:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	0	41	theme	Synthetic	41:49	arg1	Receptors					51:59	Abiotic Synthetic Receptors	33:59	Abiotic Synthetic Receptors	33:59	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	5	42	theme	signal	1141:1146	arg1	molecules					1148:1156	quorum-sensing-controlled signal molecules	1115:1156	quorum-sensing-controlled signal molecules	1115:1156	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	4	43	theme	imprinted	869:877	arg1	nanoparticles					879:891	imprinted nanoparticles	869:891	imprinted nanoparticles	869:891	The incorporation of gold nanorods into imprinted nanoparticles allows selective microbial inactivation based on photothermal treatment.					
36951486	2	44	theme	rapid	349:353	arg1	strategy					365:372	a new rapid screening strategy	343:372	a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	343:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	3	45	from	bacteria	766:773	arg1	blood					784:788	whole blood	778:788	whole blood	778:788	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	3	46	theme	constant	680:687	arg1	value					694:698	an equilibrium dissociation constant (KD) value	652:698	an equilibrium dissociation constant (KD) value of 10-12 M	652:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	2	47	from	formulation	407:417	arg1	plates					430:435	96-well plates	422:435	96-well plates	422:435	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	2	48	theme	new	345:347	arg1	strategy					365:372	a new rapid screening strategy	343:372	a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria	343:564	Here, we describe a new rapid screening strategy to determine the optimal polymer formulation on 96-well plates and then produce abiotic synthetic receptors by imprinting the surface marker lipopolysaccharide (LPS) of Gram-negative bacteria.					
36951486	5	49	theme	high	1030:1033	arg1	affinity					1035:1042	high affinity	1030:1042	high affinity for bacteria	1030:1055	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	5	50	theme	imprinted	1001:1009	arg1	nanoparticles					1011:1023	the imprinted nanoparticles	997:1023	the imprinted nanoparticles with high affinity for bacteria	997:1055	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	0	51	theme	Selective	65:73	arg1	Recognition					85:95	Selective Bacterial Recognition	65:95	Selective Bacterial Recognition	65:95	Rapid Screening and Synthesis of Abiotic Synthetic Receptors for Selective Bacterial Recognition.					
36951486	3	52	theme	M	709:709	arg1	value					694:698	an equilibrium dissociation constant (KD) value	652:698	an equilibrium dissociation constant (KD) value of 10-12 M	652:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	3	53	theme	equilibrium	655:665	arg1	KD					690:691	KD	690:691	KD	690:691	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	3	53	theme	equilibrium	655:665	arg1	constant					680:687	equilibrium dissociation constant	655:687	an equilibrium dissociation constant (KD) value of 10-12 M	652:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	5	54	theme	bacteria	1070:1077	arg1	clustering					1079:1088	bacteria clustering	1070:1088	bacteria clustering	1070:1088	We have also demonstrated that the imprinted nanoparticles with high affinity for bacteria could induce bacteria clustering, drive the expression of quorum-sensing-controlled signal molecules, and eventually enhance the productivity of the cell factory.					
36951486	3	55	theme	dissociation	667:678	arg1	KD					690:691	KD	690:691	KD	690:691	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	3	55	theme	dissociation	667:678	arg1	constant					680:687	equilibrium dissociation constant	655:687	an equilibrium dissociation constant (KD) value of 10-12 M	652:709	The resulting LPS-imprinted nanoparticles reveal remarkable affinity toward LPS with an equilibrium dissociation constant (KD) value of 10-12 M and can distinguish and selectively recognize specific bacteria in whole blood at concentrations down to 10 cells/mL.					
36951486	1	56	theme	abiotic	150:156	arg1	receptors					168:176	abiotic synthetic receptors	150:176	abiotic synthetic receptors designed to feature selective bacterial recognition properties	150:239	The major challenges that impede the preparation of abiotic synthetic receptors designed to feature selective bacterial recognition properties are the complexity, nonrobustness, and environmental adaptability of live microbes.					
35218799	1	0	theme	alginate	317:324	arg1	reactor					331:337	a surface crosslinked alginate bead reactor	295:337	a surface crosslinked alginate bead reactor	295:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	5	1	theme	BF	1263:1264	arg1	%					1258:1258	above 99.22%	1247:1258	above 99.22% of BF	1247:1264	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	1	theme	BF	1263:1264	arg1	Pb					1280:1281	Pb(II)	1280:1285	Pb(II)	1280:1285	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	1	theme	BF	1263:1264	arg1	BF					1263:1264	BF	1263:1264	BF	1263:1264	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	1	theme	BF	1263:1264	arg1	%					1275:1275	95.33%	1270:1275	95.33% of Pb(II)	1270:1285	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	2	2	theme	aqueous	625:631	arg1	solution					633:640	aqueous solution	625:640	aqueous solution of calcium chloride	625:660	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	6	3	theme	efficient	1442:1450	arg1	adsorbents					1484:1493	efficient and recyclable biopolymer-based adsorbents	1442:1493	efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1442:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	2	4	theme	network	805:811	arg1	structure					813:821	crosslinked network structure	793:821	crosslinked network structure	793:821	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	6	5	theme	biopolymer-based	1467:1482	arg1	adsorbents					1484:1493	efficient and recyclable biopolymer-based adsorbents	1442:1493	efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1442:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	1	6	theme	bead	326:329	arg1	reactor					331:337	a surface crosslinked alginate bead reactor	295:337	a surface crosslinked alginate bead reactor	295:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	3	7	theme	1425.65	998:1004	arg1	capacities					976:985	high adsorption capacities	960:985	high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g	960:1020	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	2	8	theme	co-adsorption	872:884	arg1	ability					886:892	excellent single or co-adsorption ability	852:892	excellent single or co-adsorption ability	852:892	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	5	9	dep	concentration	1364:1376	arg1	II					1360:1361	II	1360:1361	II	1360:1361	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	2	10	theme	crosslinked	793:803	arg1	structure					813:821	crosslinked network structure	793:821	crosslinked network structure	793:821	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	4	11	theme	Pb	1178:1179	arg1	Pb					1178:1179	Pb	1178:1179	Pb(II)	1178:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	%					1142:1142	99.71%	1137:1142	99.71% of MB	1137:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	BF					1161:1162	BF	1161:1162	BF	1161:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	II					1181:1182	II	1181:1182	II	1181:1182	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	MB					1147:1148	MB	1147:1148	MB	1147:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	%					1173:1173	99.97%	1168:1173	99.97% of Pb(II)	1168:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	11	theme	Pb	1178:1179	arg1	%					1156:1156	99.99%	1151:1156	99.99% of BF	1151:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	1	12	dep	crosslinked	305:315	arg1	surface					297:303	surface	297:303	surface	297:303	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	5	13	theme	binary	1313:1318	arg1	mixture					1320:1326	their binary mixture	1307:1326	their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L)	1307:1386	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	4	14	theme	BF	1161:1162	arg1	Pb					1178:1179	Pb	1178:1179	Pb(II)	1178:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	%					1142:1142	99.71%	1137:1142	99.71% of MB	1137:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	BF					1161:1162	BF	1161:1162	BF	1161:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	II					1181:1182	II	1181:1182	II	1181:1182	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	MB					1147:1148	MB	1147:1148	MB	1147:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	%					1173:1173	99.97%	1168:1173	99.97% of Pb(II)	1168:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	14	theme	BF	1161:1162	arg1	%					1156:1156	99.99%	1151:1156	99.99% of BF	1151:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	3	15	theme	390.78	990:995	arg1	capacities					976:985	high adsorption capacities	960:985	high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g	960:1020	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	1	16	theme	solution	230:237	arg1	reaction					273:280	a solution free-radical graft polymerization reaction	228:280	a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor	228:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	2	17	theme	ammonium	472:479	arg1	APS					493:495	APS	493:495	APS	493:495	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	17	theme	ammonium	472:479	arg1	persulfate					481:490	ammonium persulfate	472:490	ammonium persulfate (APS)	472:496	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	18	theme	Ca2+	562:565	arg1	ions					567:570	Ca2+ ions	562:570	Ca2+ ions	562:570	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	19	theme	droplet	375:381	arg1	surface					350:356	The outer surface	340:356	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE)	340:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	20	theme	separable	905:913	arg1	advantages					915:924	easily separable advantages	898:924	easily separable advantages	898:924	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	3	21	theme	adsorption	965:974	arg1	capacities					976:985	high adsorption capacities	960:985	high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g	960:1020	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	2	22	theme	new	768:770	arg1	beads					782:786	new composite beads	768:786	new composite beads	768:786	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	3	23	theme	optimal	931:937	arg1	bead					949:952	The optimal composite bead	927:952	The optimal composite bead	927:952	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	2	24	theme	precursor	365:373	arg1	droplet					375:381	the precursor droplet	361:381	the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE)	361:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	0	25	theme	alginate	11:18	arg1	beads					20:24	Core-shell alginate beads	0:24	Core-shell alginate beads as green reactor to synthesize grafted composite beads	0:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	4	26	theme	composite	1121:1129	arg1	bead					1131:1134	the composite bead	1117:1134	the composite bead	1117:1134	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	2	27	theme	functional	833:842	arg1	groups					844:849	abundant functional groups	824:849	abundant functional groups	824:849	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	28	theme	chloride	653:660	arg1	solution					633:640	aqueous solution	625:640	aqueous solution of calcium chloride	625:660	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	1	29	theme	sodium	155:160	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	0	30	theme	Core-shell	0:9	arg1	beads					20:24	Core-shell alginate beads	0:24	Core-shell alginate beads as green reactor to synthesize grafted composite beads	0:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	1	31	theme	free-radical	239:250	arg1	reaction					273:280	a solution free-radical graft polymerization reaction	228:280	a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor	228:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	3	32	theme	533.91 mg/g	1010:1020	arg1	capacities					976:985	high adsorption capacities	960:985	high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g	960:1020	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	2	33	theme	capsule-like	582:593	arg1	bead					595:598	a capsule-like bead	580:598	a capsule-like bead	580:598	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	1	34	theme	alginate	162:169	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	6	35	theme	recyclable	1456:1465	arg1	adsorbents					1484:1493	efficient and recyclable biopolymer-based adsorbents	1442:1493	efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1442:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	1	36	theme	graft	252:256	arg1	reaction					273:280	a solution free-radical graft polymerization reaction	228:280	a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor	228:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	3	37	theme	high	960:963	arg1	capacities					976:985	high adsorption capacities	960:985	high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g	960:1020	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	6	38	from	ions	1537:1540	arg1	water					1545:1549	water	1545:1549	water	1545:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	3	39	theme	composite	939:947	arg1	bead					949:952	The optimal composite bead	927:952	The optimal composite bead	927:952	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	5	40	theme	Pb	1357:1358	arg1	concentration					1364:1376	Pb(II) concentration	1357:1376	Pb(II) concentration	1357:1376	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	1	41	theme	polymerization	258:271	arg1	reaction					273:280	a solution free-radical graft polymerization reaction	228:280	a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor	228:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	0	42	theme	dyes	126:129	arg1	Pb					135:136	Pb	135:136	Pb(II)	135:140	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	0	42	theme	dyes	126:129	arg1	single/co-adsorption					102:121	single/co-adsorption	102:121	single/co-adsorption of dyes	102:129	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	0	42	theme	dyes	126:129	arg1	II					138:139	II	138:139	II	138:139	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	6	43	theme	green	1418:1422	arg1	way					1424:1426	a simple green way	1409:1426	a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1409:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	4	44	attach	removed	1190:1196	arg2	MB					1147:1148	MB	1147:1148	MB	1147:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	%					1156:1156	99.99%	1151:1156	99.99% of BF	1151:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	II					1181:1182	II	1181:1182	II	1181:1182	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	%					1173:1173	99.97%	1168:1173	99.97% of Pb(II)	1168:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg1	solutions					1226:1234	original dye or Pb(II) solutions	1203:1234	original dye or Pb(II) solutions	1203:1234	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	Pb					1178:1179	Pb	1178:1179	Pb(II)	1178:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	BF					1161:1162	BF	1161:1162	BF	1161:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	44	attach	removed	1190:1196	arg2	%					1142:1142	99.71%	1137:1142	99.71% of MB	1137:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	1	45	link	crosslinked	305:315	arg1	reactor					331:337	a surface crosslinked alginate bead reactor	295:337	a surface crosslinked alginate bead reactor	295:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	1	46	theme	SA	172:173	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	4	47	with	adsorption	1101:1110	arg1	bead					1131:1134	the composite bead	1117:1134	the composite bead	1117:1134	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	48	theme	dye	1212:1214	arg1	solutions					1226:1234	original dye or Pb(II) solutions	1203:1234	original dye or Pb(II) solutions	1203:1234	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	3	49	theme	Blue	1039:1042	arg1	MB					1045:1046	MB	1045:1046	MB	1045:1046	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	3	49	theme	Blue	1039:1042	arg1	Methylene					1029:1037	Methylene Blue	1029:1042	Methylene Blue (MB)	1029:1047	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	4	50	theme	MB	1147:1148	arg1	Pb					1178:1179	Pb	1178:1179	Pb(II)	1178:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	%					1142:1142	99.71%	1137:1142	99.71% of MB	1137:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	BF					1161:1162	BF	1161:1162	BF	1161:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	II					1181:1182	II	1181:1182	II	1181:1182	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	MB					1147:1148	MB	1147:1148	MB	1147:1148	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	%					1173:1173	99.97%	1168:1173	99.97% of Pb(II)	1168:1183	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	4	50	theme	MB	1147:1148	arg1	%					1156:1156	99.99%	1151:1156	99.99% of BF	1151:1162	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	0	51	theme	green	29:33	arg1	reactor					35:41	green reactor	29:41	green reactor to synthesize grafted composite beads	29:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	2	52	theme	single	862:867	arg1	ability					886:892	excellent single or co-adsorption ability	852:892	excellent single or co-adsorption ability	852:892	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	4	53	theme	Pb	1219:1220	arg1	solutions					1226:1234	original dye or Pb(II) solutions	1203:1234	original dye or Pb(II) solutions	1203:1234	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	1	54	theme	grafted	176:182	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	2	55	theme	excellent	852:860	arg1	ability					886:892	excellent single or co-adsorption ability	852:892	excellent single or co-adsorption ability	852:892	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	5	56	dep	mixture	1320:1326	arg1	concentration					1332:1344	BF concentration	1329:1344	BF concentration	1329:1344	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	56	dep	mixture	1320:1326	arg1	100 mg/L					1347:1354	100 mg/L	1347:1354	100 mg/L	1347:1354	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	56	dep	mixture	1320:1326	arg1	50 mg/L					1379:1385	50 mg/L	1379:1385	50 mg/L	1379:1385	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	2	57	theme	abundant	824:831	arg1	groups					844:849	abundant functional groups	824:849	abundant functional groups	824:849	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	0	58	dep	reactor	35:41	arg1	synthesize					46:55	synthesize	46:55	to synthesize grafted composite beads	43:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	6	59	theme	heavy	1525:1529	arg1	ions					1537:1540	heavy metal ions	1525:1540	heavy metal ions	1525:1540	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	4	60	theme	original	1203:1210	arg1	dye					1212:1214	original dye	1203:1214	original dye	1203:1214	After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions.					
35218799	5	61	dep	concentration	1332:1344	arg1	concentration					1364:1376	Pb(II) concentration	1357:1376	Pb(II) concentration	1357:1376	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	62	theme	Pb	1280:1281	arg1	%					1258:1258	above 99.22%	1247:1258	above 99.22% of BF	1247:1264	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	62	theme	Pb	1280:1281	arg1	Pb					1280:1281	Pb(II)	1280:1285	Pb(II)	1280:1285	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	62	theme	Pb	1280:1281	arg1	BF					1263:1264	BF	1263:1264	BF	1263:1264	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	62	theme	Pb	1280:1281	arg1	%					1275:1275	95.33%	1270:1275	95.33% of Pb(II)	1270:1285	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	2	63	contain	containing	383:392	arg2	SA					414:415	SA	414:415	SA	414:415	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	N'-methylene-bis-acrylamide					437:463	N'-methylene-bis-acrylamide	437:463	N'-methylene-bis-acrylamide (MBA)	437:469	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg1	droplet					375:381	the precursor droplet	361:381	the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE)	361:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	N					435:435	N	435:435	N	435:435	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	sepiolite					499:507	sepiolite	499:507	sepiolite (SP)	499:512	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	gelatin					518:524	gelatin	518:524	gelatin (GE)	518:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	persulfate					481:490	ammonium persulfate	472:490	ammonium persulfate (APS)	472:496	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	acrylamide					418:427	acrylamide	418:427	acrylamide (AM)	418:432	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	63	contain	containing	383:392	arg2	reactants					394:402	reactants	394:402	reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE)	394:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	64	theme	reactor	726:732	arg1	"					733:733	the capsule-like "bead reactor"	703:733	the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages	703:924	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	6	65	theme	capable	1495:1501	arg1	adsorbents					1484:1493	efficient and recyclable biopolymer-based adsorbents	1442:1493	efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1442:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	5	66	theme	BF	1329:1330	arg1	concentration					1332:1344	BF concentration	1329:1344	BF concentration	1329:1344	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	66	theme	BF	1329:1330	arg1	100 mg/L					1347:1354	100 mg/L	1347:1354	100 mg/L	1347:1354	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	5	66	theme	BF	1329:1330	arg1	50 mg/L					1379:1385	50 mg/L	1379:1385	50 mg/L	1379:1385	Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L).					
35218799	6	67	theme	simple	1411:1416	arg1	way					1424:1426	a simple green way	1409:1426	a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water	1409:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	2	68	theme	bead	721:724	arg1	"					733:733	the capsule-like "bead reactor"	703:733	the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages	703:924	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	1	69	theme	polymer	184:190	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	3	70	theme	Basic	1050:1054	arg1	BF					1065:1066	BF	1065:1066	BF	1065:1066	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	3	70	theme	Basic	1050:1054	arg1	Fuchsin					1056:1062	Basic Fuchsin	1050:1062	Basic Fuchsin (BF)	1050:1067	The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively.					
35218799	2	71	theme	calcium	645:651	arg1	chloride					653:660	calcium chloride	645:660	calcium chloride	645:660	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	2	72	theme	outer	344:348	arg1	surface					350:356	The outer surface	340:356	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE)	340:529	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	1	73	theme	composite	192:200	arg1	beads					202:206	sodium alginate (SA) grafted polymer composite beads	155:206	sodium alginate (SA) grafted polymer composite beads	155:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	0	74	theme	composite	65:73	arg1	beads					75:79	grafted composite beads	57:79	grafted composite beads	57:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	6	75	from	dyes	1516:1519	arg1	water					1545:1549	water	1545:1549	water	1545:1549	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	2	76	theme	capsule-like	707:718	arg1	"					733:733	the capsule-like "bead reactor"	703:733	the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages	703:924	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	1	77	theme	beads	202:206	arg1	series					145:150	A series	143:150	A series of sodium alginate (SA) grafted polymer composite beads	143:206	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	0	78	theme	grafted	57:63	arg1	beads					75:79	grafted composite beads	57:79	grafted composite beads	57:79	Core-shell alginate beads as green reactor to synthesize grafted composite beads to efficiently boost single/co-adsorption of dyes and Pb(II).					
35218799	1	79	theme	crosslinked	305:315	arg1	reactor					331:337	a surface crosslinked alginate bead reactor	295:337	a surface crosslinked alginate bead reactor	295:337	A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor.					
35218799	2	80	link	crosslinked	793:803	arg1	structure					813:821	crosslinked network structure	793:821	crosslinked network structure	793:821	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
35218799	6	81	theme	metal	1531:1535	arg1	ions					1537:1540	heavy metal ions	1525:1540	heavy metal ions	1525:1540	This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.					
35218799	2	82	theme	composite	772:780	arg1	beads					782:786	new composite beads	768:786	new composite beads	768:786	The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N'-methylene-bis-acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride, and simultaneously the reactants inside the capsule-like "bead reactor" were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages.					
37111208	4	0	theme	carotenoid	526:535	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	1	1	theme	models	210:215	arg1	diet					150:153	the Alpine diet	139:153	the Alpine diet	139:153	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	1	1	theme	models	210:215	arg1	models					210:215	the most common nutritional models	182:215	the most common nutritional models	182:215	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	1	1	theme	models	210:215	arg1	one					175:177	one	175:177	one	175:177	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	4	2	theme	total	538:542	arg1	phenol					544:549	total phenol	538:549	total phenol	538:549	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	2	3	theme	animal-based	238:249	arg1	products					251:258	traditional animal-based products	226:258	traditional animal-based products	226:258	Next to traditional animal-based products, spontaneous plants of the territory are collected and eaten.					
37111208	8	4	theme	p	1455:1455	arg1	gnocchi					1446:1452	matched control gnocchi	1430:1452	matched control gnocchi (p < 0.05)	1430:1463	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	8	4	theme	p	1455:1455	arg1	<					1457:1457	p < 0.05	1455:1462	p < 0.05	1455:1462	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	6	5	theme	magnesium	1017:1025	arg1	dioica					942:947	Urtica dioica	935:947	Urtica dioica	935:947	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	5	theme	magnesium	1017:1025	arg1	source					988:993	a good dietary source	973:993	a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW)	973:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	4	6	theme	plant	591:595	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	8	7	dep	%	1300:1300	arg1	starch					1315:1320	SDS/available starch	1301:1320	%SDS/available starch	1300:1320	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	1	8	theme	Alpine	143:148	arg1	diet					150:153	the Alpine diet	139:153	the Alpine diet	139:153	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	1	8	theme	Alpine	143:148	arg1	models					210:215	the most common nutritional models	182:215	the most common nutritional models	182:215	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	1	8	theme	Alpine	143:148	arg1	one					175:177	one	175:177	one	175:177	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	6	9	theme	highest	876:882	arg1	levels					884:889	the highest levels	872:889	the highest levels of total phenols (554 mg GAE/100 g FW)	872:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	0	10	theme	Traditional	92:102	arg1	Dishes					104:109	Traditional Dishes	92:109	Traditional Dishes	92:109	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	9	11	theme	Traditional	1478:1488	arg1	consumption					1490:1500	CONCLUSIONS Traditional consumption	1466:1500	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions	1466:1544	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	5	12	theme	high	779:782	arg1	levels					784:789	high levels	779:789	high levels of carotenoids (15-20 mg/100 g FW)	779:824	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	6	13	theme	Rumex	851:855	arg1	acetosa					857:863	Rumex acetosa	851:863	Rumex acetosa	851:863	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	14	theme	mg/100	1045:1050	arg1	magnesium					1017:1025	magnesium	1017:1025	magnesium (4.9, 410, and 72 mg/100 g FW)	1017:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	14	theme	mg/100	1045:1050	arg1	FW					1054:1055	4.9, 410, and 72 mg/100 g FW	1028:1055	4.9, 410, and 72 mg/100 g FW	1028:1055	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	9	15	theme	plants	1517:1522	arg1	consumption					1490:1500	CONCLUSIONS Traditional consumption	1466:1500	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions	1466:1544	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	7	16	theme	Silene	1230:1235	arg1	vulgaris					1237:1244	Silene vulgaris	1230:1244	Silene vulgaris (p < 0.05)	1230:1255	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	16	theme	Silene	1230:1235	arg1	<					1249:1249	p < 0.05	1247:1254	p < 0.05	1247:1254	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	6	17	theme	GAE/100	916:922	arg1	phenols					900:906	total phenols	894:906	total phenols (554 mg GAE/100 g FW)	894:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	17	theme	GAE/100	916:922	arg1	FW					926:927	554 mg GAE/100 g FW	909:927	554 mg GAE/100 g FW	909:927	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	8	18	theme	digestible	1269:1278	arg1	%					1300:1300	%SDS/available starch	1300:1320	%SDS/available starch	1300:1320	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	8	18	theme	digestible	1269:1278	arg1	fraction					1280:1287	The slowly digestible fraction	1258:1287	The slowly digestible fraction	1258:1287	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	7	19	theme	total	1153:1157	arg1	phenols					1159:1165	total phenols	1153:1165	total phenols	1153:1165	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	4	20	theme	chemical	613:620	arg1	composition					622:632	the chemical composition	609:632	the chemical composition	609:632	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	5	21	theme	mg/100	813:818	arg1	FW					822:823	15-20 mg/100 g FW	807:823	15-20 mg/100 g FW	807:823	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	5	21	theme	mg/100	813:818	arg1	carotenoids					794:804	carotenoids	794:804	carotenoids (15-20 mg/100 g FW)	794:824	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	0	22	theme	Nutritional	45:55	arg1	Features					57:64	Nutritional Features	45:64	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.	0:110	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	6	23	theme	phenols	900:906	arg1	levels					884:889	the highest levels	872:889	the highest levels of total phenols (554 mg GAE/100 g FW)	872:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	9	24	theme	dietary	1565:1571	arg1	intakes					1573:1579	the dietary intakes	1561:1579	the dietary intakes of several bioactive substances	1561:1611	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	8	25	theme	SDS/available	1301:1313	arg1	starch					1315:1320	SDS/available starch	1301:1320	%SDS/available starch	1300:1320	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	0	26	theme	Plants	81:86	arg1	Features					57:64	Nutritional Features	45:64	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.	0:110	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	5	27	contain	contained	769:777	arg1	RESULTS					713:719	RESULTS	713:719	RESULTS Except for Aruncus dioicus, all the wild plants	713:767	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	5	27	contain	contained	769:777	arg2	levels					784:789	high levels	779:789	high levels of carotenoids (15-20 mg/100 g FW)	779:824	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	4	28	theme	green	671:675	arg1	gnocchi					689:695	green and control gnocchi	671:695	gnocchi	689:695	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	0	29	theme	Alpine	0:5	arg1	Diet					7:10	Alpine Diet	0:10	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.	0:110	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	9	30	theme	bioactive	1592:1600	arg1	substances					1602:1611	several bioactive substances	1584:1611	several bioactive substances	1584:1611	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	4	31	theme	control	681:687	arg1	gnocchi					689:695	green and control gnocchi	671:695	gnocchi	689:695	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	3	32	theme	plants	414:419	arg1	features					379:386	the nutritional features	363:386	the nutritional features of selected autochthonous plants of the territory	363:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	3	32	theme	plants	414:419	arg1	recipe					454:459	the typical recipe	442:459	the typical recipe of green gnocchi	442:476	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	4	33	from	analyses	491:498	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	3	34	theme	gnocchi	470:476	arg1	features					379:386	the nutritional features	363:386	the nutritional features of selected autochthonous plants of the territory	363:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	3	34	theme	gnocchi	470:476	arg1	recipe					454:459	the typical recipe	442:459	the typical recipe of green gnocchi	442:476	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	4	35	dep	in	638:639	arg1	vitro					641:645	vitro	641:645	vitro	641:645	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	4	36	theme	proximate	503:511	arg1	composition					513:523	proximate composition	503:523	proximate composition	503:523	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	3	37	theme	selected	391:398	arg1	plants					414:419	selected autochthonous plants	391:419	selected autochthonous plants of the territory	391:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	4	38	from	METHODS	479:485	arg1	gnocchi					689:695	green and control gnocchi	671:695	gnocchi	689:695	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	3	39	theme	study	342:346	arg1	aim					330:332	The aim	326:332	The aim of this study	326:346	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	2	40	theme	territory	287:295	arg1	plants					273:278	spontaneous plants	261:278	spontaneous plants of the territory	261:295	Next to traditional animal-based products, spontaneous plants of the territory are collected and eaten.					
37111208	8	41	theme	matched	1430:1436	arg1	gnocchi					1446:1452	matched control gnocchi	1430:1452	matched control gnocchi (p < 0.05)	1430:1463	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	8	41	theme	matched	1430:1436	arg1	<					1457:1457	p < 0.05	1455:1462	p < 0.05	1455:1462	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	6	42	theme	good	975:978	arg1	dioica					942:947	Urtica dioica	935:947	Urtica dioica	935:947	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	42	theme	good	975:978	arg1	source					988:993	a good dietary source	973:993	a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW)	973:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	4	43	theme	phenol	544:549	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	9	44	theme	micronutrients	1662:1675	arg1	nutritional					1641:1651	nutritional	1641:1651	nutritional	1641:1651	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	3	45	theme	typical	446:452	arg1	recipe					454:459	the typical recipe	442:459	the typical recipe of green gnocchi	442:476	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	4	46	from	composition	622:632	arg1	gnocchi					689:695	green and control gnocchi	671:695	gnocchi	689:695	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	1	47	theme	nutritional	198:208	arg1	models					210:215	the most common nutritional models	182:215	the most common nutritional models	182:215	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	8	48	theme	green	1404:1408	arg1	gnocchi					1410:1416	green gnocchi	1404:1416	green gnocchi	1404:1416	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	7	49	theme	p	1247:1247	arg1	vulgaris					1237:1244	Silene vulgaris	1230:1244	Silene vulgaris (p < 0.05)	1230:1255	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	49	theme	p	1247:1247	arg1	<					1249:1249	p < 0.05	1247:1254	p < 0.05	1247:1254	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	2	50	theme	traditional	226:236	arg1	products					251:258	traditional animal-based products	226:258	traditional animal-based products	226:258	Next to traditional animal-based products, spontaneous plants of the territory are collected and eaten.					
37111208	4	51	from	samples	597:603	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	4	52	theme	cooked	584:589	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	4	53	from	phenol	544:549	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	5	54	theme	carotenoids	794:804	arg1	levels					784:789	high levels	779:789	high levels of carotenoids (15-20 mg/100 g FW)	779:824	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	6	55	theme	calcium	1004:1010	arg1	dioica					942:947	Urtica dioica	935:947	Urtica dioica	935:947	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	55	theme	calcium	1004:1010	arg1	source					988:993	a good dietary source	973:993	a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW)	973:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	0	56	theme	Dishes	104:109	arg1	Features					57:64	Nutritional Features	45:64	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.	0:110	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	2	57	theme	spontaneous	261:271	arg1	plants					273:278	spontaneous plants	261:278	spontaneous plants of the territory	261:295	Next to traditional animal-based products, spontaneous plants of the territory are collected and eaten.					
37111208	5	58	theme	wild	757:760	arg1	plants					762:767	all the wild plants	749:767	all the wild plants	749:767	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	5	58	theme	wild	757:760	arg1	dioicus					740:746	Aruncus dioicus	732:746	Aruncus dioicus	732:746	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	9	59	theme	CONCLUSIONS	1466:1476	arg1	consumption					1490:1500	CONCLUSIONS Traditional consumption	1466:1500	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions	1466:1544	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	6	60	theme	iron	998:1001	arg1	dioica					942:947	Urtica dioica	935:947	Urtica dioica	935:947	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	60	theme	iron	998:1001	arg1	source					988:993	a good dietary source	973:993	a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW)	973:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	4	61	theme	contents	564:571	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	4	62	from	contents	564:571	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	4	63	from	digestibility	654:666	arg1	gnocchi					689:695	green and control gnocchi	671:695	gnocchi	689:695	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	9	64	from	consumption	1490:1500	arg1	regions					1538:1544	the Alpine regions	1527:1544	the Alpine regions	1527:1544	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	6	65	theme	g	1052:1052	arg1	magnesium					1017:1025	magnesium	1017:1025	magnesium (4.9, 410, and 72 mg/100 g FW)	1017:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	65	theme	g	1052:1052	arg1	FW					1054:1055	4.9, 410, and 72 mg/100 g FW	1028:1055	4.9, 410, and 72 mg/100 g FW	1028:1055	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	4	66	theme	raw	576:578	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	9	67	theme	spontaneous	1505:1515	arg1	plants					1517:1522	spontaneous plants	1505:1522	spontaneous plants	1505:1522	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	4	68	theme	in	638:639	arg1	digestibility					654:666	in vitro starch digestibility	638:666	in vitro starch digestibility	638:666	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	6	69	theme	g	924:924	arg1	phenols					900:906	total phenols	894:906	total phenols (554 mg GAE/100 g FW)	894:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	69	theme	g	924:924	arg1	FW					926:927	554 mg GAE/100 g FW	909:927	554 mg GAE/100 g FW	909:927	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	4	70	theme	starch	647:652	arg1	digestibility					654:666	in vitro starch digestibility	638:666	in vitro starch digestibility	638:666	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	6	71	theme	mg	913:914	arg1	phenols					900:906	total phenols	894:906	total phenols (554 mg GAE/100 g FW)	894:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	71	theme	mg	913:914	arg1	FW					926:927	554 mg GAE/100 g FW	909:927	554 mg GAE/100 g FW	909:927	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	9	72	theme	Alpine	1531:1536	arg1	regions					1538:1544	the Alpine regions	1527:1544	the Alpine regions	1527:1544	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	8	73	theme	starch	1292:1297	arg1	%					1300:1300	%SDS/available starch	1300:1320	%SDS/available starch	1300:1320	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	8	73	theme	starch	1292:1297	arg1	fraction					1280:1287	The slowly digestible fraction	1258:1287	The slowly digestible fraction	1258:1287	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	4	74	dep	METHODS	479:485	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	5	75	theme	g	820:820	arg1	FW					822:823	15-20 mg/100 g FW	807:823	15-20 mg/100 g FW	807:823	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	5	75	theme	g	820:820	arg1	carotenoids					794:804	carotenoids	794:804	carotenoids (15-20 mg/100 g FW)	794:824	RESULTS Except for Aruncus dioicus, all the wild plants contained high levels of carotenoids (15-20 mg/100 g FW), mainly as xanthophylls.					
37111208	0	76	from	Diet	7:10	arg1	Valmalenco					15:24	Valmalenco	15:24	Valmalenco	15:24	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	0	77	theme	Spontaneous	69:79	arg1	Plants					81:86	Spontaneous Plants	69:86	Spontaneous Plants	69:86	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	6	78	theme	total	894:898	arg1	phenols					900:906	total phenols	894:906	total phenols (554 mg GAE/100 g FW)	894:928	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	78	theme	total	894:898	arg1	FW					926:927	554 mg GAE/100 g FW	909:927	554 mg GAE/100 g FW	909:927	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	1	79	dep	BACKGROUND	112:121	arg1	considered					158:167	considered	158:167	is considered to be one of the most common nutritional models	155:215	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37111208	4	80	from	carotenoid	526:535	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	8	81	dep	increased	1391:1399	arg1	compared					1418:1425	compared	1418:1425	compared to matched control gnocchi (p < 0.05)	1418:1463	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	9	82	dep	nutritional	1641:1651	arg1	needs					1653:1657	needs	1653:1657	needs	1653:1657	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	7	83	from	phenols	1159:1165	arg1	vulgaris					1237:1244	Silene vulgaris	1230:1244	Silene vulgaris (p < 0.05)	1230:1255	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	83	from	phenols	1159:1165	arg1	<					1249:1249	p < 0.05	1247:1254	p < 0.05	1247:1254	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	83	from	phenols	1159:1165	arg1	dioicus					1194:1200	Aruncus dioicus	1186:1200	Aruncus dioicus	1186:1200	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	83	from	phenols	1159:1165	arg1	bonus-henricus					1210:1223	Blitum bonus-henricus	1203:1223	Blitum bonus-henricus	1203:1223	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	83	from	phenols	1159:1165	arg1	species					1140:1146	all wild species	1131:1146	all wild species	1131:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	4	84	from	composition	513:523	arg1	samples					597:603	raw and cooked plant samples	576:603	samples	597:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	7	85	from	carotenoids	1171:1181	arg1	species					1140:1146	all wild species	1131:1146	all wild species	1131:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	85	from	carotenoids	1171:1181	arg1	<					1249:1249	p < 0.05	1247:1254	p < 0.05	1247:1254	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	85	from	carotenoids	1171:1181	arg1	dioicus					1194:1200	Aruncus dioicus	1186:1200	Aruncus dioicus	1186:1200	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	85	from	carotenoids	1171:1181	arg1	bonus-henricus					1210:1223	Blitum bonus-henricus	1203:1223	Blitum bonus-henricus	1203:1223	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	85	from	carotenoids	1171:1181	arg1	vulgaris					1237:1244	Silene vulgaris	1230:1244	Silene vulgaris (p < 0.05)	1230:1255	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	86	theme	wild	1135:1138	arg1	species					1140:1146	all wild species	1131:1146	all wild species	1131:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	9	87	theme	several	1584:1590	arg1	substances					1602:1611	several bioactive substances	1584:1611	several bioactive substances	1584:1611	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	3	88	theme	nutritional	367:377	arg1	features					379:386	the nutritional features	363:386	the nutritional features of selected autochthonous plants of the territory	363:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	9	89	theme	substances	1602:1611	arg1	intakes					1573:1579	the dietary intakes	1561:1579	the dietary intakes of several bioactive substances	1561:1611	CONCLUSIONS Traditional consumption of spontaneous plants in the Alpine regions might increase the dietary intakes of several bioactive substances and contribute to cover the nutritional needs of micronutrients.					
37111208	4	90	theme	composition	513:523	arg1	analyses					491:498	The analyses	487:498	The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples	487:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	7	91	theme	magnesium	1109:1117	arg1	contents					1119:1126	the potassium and magnesium contents	1091:1126	the potassium and magnesium contents in all wild species	1091:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	8	92	theme	insulin	1357:1363	arg1	demand					1365:1370	insulin demand	1357:1370	insulin demand	1357:1370	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	3	93	theme	autochthonous	400:412	arg1	plants					414:419	selected autochthonous plants	391:419	selected autochthonous plants of the territory	391:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	7	94	from	contents	1119:1126	arg1	species					1140:1146	all wild species	1131:1146	all wild species	1131:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	94	from	contents	1119:1126	arg1	<					1249:1249	p < 0.05	1247:1254	p < 0.05	1247:1254	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	94	from	contents	1119:1126	arg1	dioicus					1194:1200	Aruncus dioicus	1186:1200	Aruncus dioicus	1186:1200	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	94	from	contents	1119:1126	arg1	bonus-henricus					1210:1223	Blitum bonus-henricus	1203:1223	Blitum bonus-henricus	1203:1223	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	94	from	contents	1119:1126	arg1	vulgaris					1237:1244	Silene vulgaris	1230:1244	Silene vulgaris (p < 0.05)	1230:1255	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	7	95	theme	potassium	1095:1103	arg1	contents					1119:1126	the potassium and magnesium contents	1091:1126	the potassium and magnesium contents in all wild species	1091:1146	Cooking significantly decreased the potassium and magnesium contents in all wild species, and total phenols and carotenoids in Aruncus dioicus, Blitum bonus-henricus, and Silene vulgaris (p < 0.05).					
37111208	8	96	theme	control	1438:1444	arg1	gnocchi					1446:1452	matched control gnocchi	1430:1452	matched control gnocchi (p < 0.05)	1430:1463	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	8	96	theme	control	1438:1444	arg1	<					1457:1457	p < 0.05	1455:1462	p < 0.05	1455:1462	The slowly digestible fraction of starch (%SDS/available starch), which is inversely correlated to insulin demand, was significantly increased in green gnocchi compared to matched control gnocchi (p < 0.05).					
37111208	6	97	theme	dietary	980:986	arg1	dioica					942:947	Urtica dioica	935:947	Urtica dioica	935:947	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	6	97	theme	dietary	980:986	arg1	source					988:993	a good dietary source	973:993	a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW)	973:1056	Rumex acetosa showed the highest levels of total phenols (554 mg GAE/100 g FW), and Urtica dioica can be considered to be a good dietary source of iron, calcium, and magnesium (4.9, 410, and 72 mg/100 g FW).					
37111208	3	98	dep	AIM	322:324	arg1	is					348:349	is	348:349	is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi	348:476	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	3	99	theme	territory	428:436	arg1	plants					414:419	selected autochthonous plants	391:419	selected autochthonous plants of the territory	391:436	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	0	100	dep	Diet	7:10	arg1	Lombardy					27:34	Lombardy	27:34	Lombardy	27:34	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	0	100	dep	Diet	7:10	arg1	Features					57:64	Nutritional Features	45:64	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.	0:110	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	0	100	dep	Diet	7:10	arg1	Italy					37:41	Italy	37:41	Italy	37:41	Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.					
37111208	4	101	theme	mineral	556:562	arg1	contents					564:571	mineral contents	556:571	mineral contents in raw and cooked plant samples	556:603	METHODS The analyses of proximate composition, carotenoid, total phenol, and mineral contents in raw and cooked plant samples and the chemical composition and in vitro starch digestibility in green and control gnocchi were performed.					
37111208	3	102	theme	green	464:468	arg1	gnocchi					470:476	green gnocchi	464:476	green gnocchi	464:476	AIM The aim of this study is to evaluate the nutritional features of selected autochthonous plants of the territory and the typical recipe of green gnocchi.					
37111208	1	103	theme	common	191:196	arg1	models					210:215	the most common nutritional models	182:215	the most common nutritional models	182:215	BACKGROUND Along the Alps, the Alpine diet is considered to be one of the most common nutritional models.					
37081437	11	0	from	proteins	1290:1297	arg1	rich					1262:1265	rich	1262:1265	rich	1262:1265	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	12	1	theme	fluorescent	1478:1488	arg1	mCherry					1499:1505	fluorescent reporter mCherry	1478:1505	fluorescent reporter mCherry	1478:1505	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	9	2	theme	media	1012:1016	arg1	albumin					1041:1047	media component bovine serum albumin	1012:1047	media component bovine serum albumin	1012:1047	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	14	3	theme	biofilms	1835:1842	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	9	4	dep	DTT	1105:1107	arg1	response					1093:1100	response	1093:1100	response	1093:1100	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	9	5	theme	bovine	1028:1033	arg1	albumin					1041:1047	media component bovine serum albumin	1012:1047	media component bovine serum albumin	1012:1047	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	1	6	theme	relevant	188:195	arg1	biofilms					197:204	physiologically relevant biofilms	172:204	physiologically relevant biofilms harboring drug-tolerant bacteria	172:237	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	17	7	theme	plant	2204:2208	arg1	cells					2210:2214	plant cells	2204:2214	plant cells	2204:2214	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	16	8	theme	nucleating	2001:2010	arg1	foci					2012:2015	These nucleating foci	1995:2015	These nucleating foci	1995:2015	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	9	9	theme	mycobacterial	1058:1070	arg1	formation					1080:1088	mycobacterial biofilm formation	1058:1088	mycobacterial biofilm formation	1058:1088	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	14	10	theme	Msm	1831:1833	arg1	biofilms					1835:1842	Msm biofilms	1831:1842	Msm biofilms using this novel probe	1831:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	13	11	theme	Agrobacterium	1677:1689	arg1	biofilms					1691:1698	Agrobacterium biofilms	1677:1698	Agrobacterium biofilms	1677:1698	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	7	12	theme	Msm	877:879	arg1	cultures					881:888	Msm cultures	877:888	Msm cultures	877:888	We observed that DTT induces biofilm formation in Msm cultures.					
37081437	12	13	theme	CenA	1433:1436	arg1	domain					1413:1418	the cellulose-binding domain	1391:1418	the cellulose-binding domain of cellulase CenA	1391:1436	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	12	13	theme	CenA	1433:1436	arg1	CenA					1433:1436	cellulase CenA	1423:1436	cellulase CenA	1423:1436	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	17	14	theme	cellulose	2231:2239	arg1	dynamics					2254:2261	cellulose biosynthesis dynamics	2231:2261	cellulose biosynthesis dynamics	2231:2261	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	13	15	theme	cellulose	1628:1636	arg1	biosynthesis					1638:1649	cellulose biosynthesis	1628:1649	cellulose biosynthesis	1628:1649	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	5	16	theme	limited	595:601	arg1	tools					603:607	only limited tools	590:607	only limited tools for monitoring the presence of cellulose in biofilms	590:660	Furthermore, there are only limited tools for monitoring the presence of cellulose in biofilms.					
37081437	12	17	theme	Cellulomonas	1443:1454	arg1	fimi					1456:1459	Cellulomonas fimi	1443:1459	Cellulomonas fimi	1443:1459	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	14	18	from	present	1778:1784	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	14	19	theme	extracellular	1793:1805	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	1	20	theme	BACKGROUND	122:131	arg1	Mtb					161:163	Mtb	161:163	Mtb	161:163	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	1	20	theme	BACKGROUND	122:131	arg1	tuberculosis					147:158	BACKGROUND Mycobacterium tuberculosis	122:158	BACKGROUND Mycobacterium tuberculosis (Mtb)	122:164	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	12	21	theme	cellulose-binding	1395:1411	arg1	domain					1413:1418	the cellulose-binding domain	1391:1418	the cellulose-binding domain of cellulase CenA	1391:1436	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	12	21	theme	cellulose-binding	1395:1411	arg1	CenA					1433:1436	cellulase CenA	1423:1436	cellulase CenA	1423:1436	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	11	22	from	rich	1262:1265	arg1	proteins					1290:1297	proteins	1290:1297	proteins	1290:1297	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	11	22	from	rich	1262:1265	arg1	polysaccharides					1270:1284	polysaccharides	1270:1284	polysaccharides	1270:1284	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	2	23	theme	mycobacterial	282:294	arg1	biofilms					296:303	mycobacterial biofilms	282:303	mycobacterial biofilms	282:303	This observation has brought the study of mycobacterial biofilms to the forefront of tuberculosis research.					
37081437	5	24	from	presence	628:635	arg1	biofilms					653:660	biofilms	653:660	biofilms	653:660	Furthermore, there are only limited tools for monitoring the presence of cellulose in biofilms.					
37081437	11	25	from	polysaccharides	1270:1284	arg1	rich					1262:1265	rich	1262:1265	rich	1262:1265	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	10	26	theme	polymeric	1168:1176	arg1	substances					1178:1187	extracellular polymeric substances	1154:1187	extracellular polymeric substances of Msm biofilms	1154:1203	Furthermore, we analyzed the composition of extracellular polymeric substances of Msm biofilms.					
37081437	0	27	theme	biofilms	80:87	arg1	formation					53:61	the formation	49:61	the formation of mycobacterial biofilms in response to reductive stress	49:119	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	14	28	theme	macromolecule	1751:1763	arg1	cellulose					1765:1773	biological macromolecule cellulose	1740:1773	biological macromolecule cellulose	1740:1773	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	10	29	theme	biofilms	1196:1203	arg1	substances					1178:1187	extracellular polymeric substances	1154:1187	extracellular polymeric substances of Msm biofilms	1154:1203	Furthermore, we analyzed the composition of extracellular polymeric substances of Msm biofilms.					
37081437	15	30	dep	CONCLUSIONS	1868:1878	arg1	indicates					1891:1899	indicates	1891:1899	indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci	1891:1992	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	16	31	theme	production	2096:2105	arg1	induction					2079:2087	induction	2079:2087	induction of EPS production	2079:2105	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	16	31	theme	production	2096:2105	arg1	attachment					2045:2054	subsequent attachment	2034:2054	subsequent attachment of bacterial cells	2034:2073	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	8	32	theme	biofilm	939:945	arg1	formation					947:955	biofilm formation	939:955	biofilm formation in mycobacteria	939:971	We explored whether media components facilitate biofilm formation in mycobacteria upon exposure to DTT.					
37081437	4	33	theme	DTT-induced	522:532	arg1	formation					542:550	the DTT-induced biofilm formation	518:550	the DTT-induced biofilm formation	518:550	The molecular events associated with the DTT-induced biofilm formation are not known.					
37081437	15	34	theme	component	1938:1946	arg1	BSA					1948:1950	media component BSA	1932:1950	media component BSA	1932:1950	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	0	35	theme	reductive	104:112	arg1	stress					114:119	reductive stress	104:119	reductive stress	104:119	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	11	36	theme	Msm	1240:1242	arg1	biofilms					1244:1251	Msm biofilms	1240:1251	Msm biofilms	1240:1251	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	15	37	theme	BSA	1948:1950	arg1	reduction					1919:1927	DTT-mediated reduction	1906:1927	DTT-mediated reduction of media component BSA	1906:1950	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	0	38	theme	Media	0:4	arg1	component					6:14	Media component bovine serum albumin	0:35	Media component bovine serum albumin	0:35	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	3	39	theme	reductive	406:414	arg1	stress					416:421	dithiothreitol (DTT) mediated reductive stress	376:421	dithiothreitol (DTT) mediated reductive stress	376:421	We established earlier that dithiothreitol (DTT) mediated reductive stress induces cellulose-rich biofilm formation in Mtb cultures.					
37081437	15	40	theme	DTT-mediated	1906:1917	arg1	reduction					1919:1927	DTT-mediated reduction	1906:1927	DTT-mediated reduction of media component BSA	1906:1950	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	0	41	theme	bovine	16:21	arg1	albumin					29:35	bovine serum albumin	16:35	Media component bovine serum albumin	0:35	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	12	42	theme	protein-based	1326:1338	arg1	probe					1350:1354	a novel protein-based molecular probe	1318:1354	a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry	1318:1505	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	6	43	theme	biofilm	732:738	arg1	formation					740:748	DTT-induced biofilm formation	720:748	DTT-induced biofilm formation	720:748	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	3	44	theme	biofilm	446:452	arg1	formation					454:462	cellulose-rich biofilm formation	431:462	cellulose-rich biofilm formation	431:462	We established earlier that dithiothreitol (DTT) mediated reductive stress induces cellulose-rich biofilm formation in Mtb cultures.					
37081437	14	45	attach	present	1778:1784	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	14	45	attach	present	1778:1784	arg2	cellulose					1765:1773	biological macromolecule cellulose	1740:1773	biological macromolecule cellulose	1740:1773	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	13	46	theme	new	1533:1535	arg1	probe					1537:1541	this new probe	1528:1541	this new probe	1528:1541	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	16	47	theme	bacterial	2059:2067	arg1	cells					2069:2073	bacterial cells	2059:2073	bacterial cells	2059:2073	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	15	48	theme	nucleating	1978:1987	arg1	foci					1989:1992	nucleating foci	1978:1992	nucleating foci	1978:1992	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	6	49	theme	Mycobacterium	796:808	arg1	Msm					821:823	Msm	821:823	Msm	821:823	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	6	49	theme	Mycobacterium	796:808	arg1	smegmatis					810:818	non-pathogenic, fast-growing Mycobacterium smegmatis	767:818	non-pathogenic, fast-growing Mycobacterium smegmatis (Msm)	767:824	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	14	50	theme	novel	1855:1859	arg1	probe					1861:1865	this novel probe	1850:1865	this novel probe	1850:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	17	51	theme	biofilm	2270:2276	arg1	etc					2289:2291	etc	2289:2291	etc	2289:2291	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	17	51	theme	biofilm	2270:2276	arg1	formation					2278:2286	biofilm formation	2270:2286	biofilm formation	2270:2286	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	13	52	theme	biofilms	1691:1698	arg1	development					1662:1672	the development	1658:1672	the development of Agrobacterium biofilms	1658:1698	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	17	53	theme	new	2126:2128	arg1	IMT-CBD-mC					2136:2145	IMT-CBD-mC	2136:2145	IMT-CBD-mC	2136:2145	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	17	53	theme	new	2126:2128	arg1	tool					2130:2133	this new tool	2121:2133	this new tool	2121:2133	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	9	54	theme	component	1018:1026	arg1	albumin					1041:1047	media component bovine serum albumin	1012:1047	media component bovine serum albumin	1012:1047	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	13	55	used	used	1607:1610	arg2	it					1557:1558	it	1557:1558	it	1557:1558	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	12	56	theme	reporter	1490:1497	arg1	mCherry					1499:1505	fluorescent reporter mCherry	1478:1505	fluorescent reporter mCherry	1478:1505	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	9	57	theme	serum	1035:1039	arg1	albumin					1041:1047	media component bovine serum albumin	1012:1047	media component bovine serum albumin	1012:1047	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	14	58	from	substances	1817:1826	arg1	present					1778:1784	present	1778:1784	present	1778:1784	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	2	59	theme	research	338:345	arg1	forefront					312:320	the forefront	308:320	the forefront of tuberculosis research	308:345	This observation has brought the study of mycobacterial biofilms to the forefront of tuberculosis research.					
37081437	1	60	theme	drug-tolerant	216:228	arg1	bacteria					230:237	drug-tolerant bacteria	216:237	drug-tolerant bacteria	216:237	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	9	61	theme	biofilm	1072:1078	arg1	formation					1080:1088	mycobacterial biofilm formation	1058:1088	mycobacterial biofilm formation	1058:1088	We observed that media component bovine serum albumin promotes mycobacterial biofilm formation in response to DTT.					
37081437	16	62	theme	subsequent	2034:2043	arg1	attachment					2045:2054	subsequent attachment	2034:2054	subsequent attachment of bacterial cells	2034:2073	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	12	63	theme	cellulase	1423:1431	arg1	CenA					1433:1436	cellulase CenA	1423:1436	cellulase CenA	1423:1436	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	17	64	theme	biosynthesis	2241:2252	arg1	dynamics					2254:2261	cellulose biosynthesis dynamics	2231:2261	cellulose biosynthesis dynamics	2231:2261	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	14	65	theme	polymeric	1807:1815	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	14	66	located	present	1778:1784	arg1	substances					1817:1826	the extracellular polymeric substances	1789:1826	the extracellular polymeric substances of Msm biofilms using this novel probe	1789:1865	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	14	66	located	present	1778:1784	arg2	cellulose					1765:1773	biological macromolecule cellulose	1740:1773	biological macromolecule cellulose	1740:1773	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	6	67	theme	DTT-induced	720:730	arg1	formation					740:748	DTT-induced biofilm formation	720:748	DTT-induced biofilm formation	720:748	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	13	68	contain	has	1560:1562	arg1	it					1557:1558	it	1557:1558	it	1557:1558	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	13	68	contain	has	1560:1562	arg2	affinity					1571:1578	a high affinity	1564:1578	a high affinity for cellulose	1564:1592	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	2	69	theme	biofilms	296:303	arg1	study					273:277	the study	269:277	the study of mycobacterial biofilms to the forefront of tuberculosis research	269:345	This observation has brought the study of mycobacterial biofilms to the forefront of tuberculosis research.					
37081437	1	70	theme	Mycobacterium	133:145	arg1	Mtb					161:163	Mtb	161:163	Mtb	161:163	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	1	70	theme	Mycobacterium	133:145	arg1	tuberculosis					147:158	BACKGROUND Mycobacterium tuberculosis	122:158	BACKGROUND Mycobacterium tuberculosis (Mtb)	122:164	BACKGROUND Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria.					
37081437	4	71	theme	molecular	485:493	arg1	events					495:500	The molecular events	481:500	The molecular events associated with the DTT-induced biofilm formation	481:550	The molecular events associated with the DTT-induced biofilm formation are not known.					
37081437	0	72	theme	mycobacterial	66:78	arg1	biofilms					80:87	mycobacterial biofilms	66:87	mycobacterial biofilms	66:87	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	6	73	theme	molecular	687:695	arg1	events					697:702	the molecular events	683:702	the molecular events associated with DTT-induced biofilm formation	683:748	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	10	74	theme	extracellular	1154:1166	arg1	substances					1178:1187	extracellular polymeric substances	1154:1187	extracellular polymeric substances of Msm biofilms	1154:1203	Furthermore, we analyzed the composition of extracellular polymeric substances of Msm biofilms.					
37081437	4	75	theme	biofilm	534:540	arg1	formation					542:550	the DTT-induced biofilm formation	518:550	the DTT-induced biofilm formation	518:550	The molecular events associated with the DTT-induced biofilm formation are not known.					
37081437	17	76	theme	cellulose	2177:2185	arg1	incorporation					2187:2199	cellulose incorporation	2177:2199	cellulose incorporation in plant cells	2177:2214	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	14	77	theme	biological	1740:1749	arg1	cellulose					1765:1773	biological macromolecule cellulose	1740:1773	biological macromolecule cellulose	1740:1773	Furthermore, we have demonstrated that biological macromolecule cellulose is present in the extracellular polymeric substances of Msm biofilms using this novel probe.					
37081437	8	78	theme	media	911:915	arg1	components					917:926	media components	911:926	media components	911:926	We explored whether media components facilitate biofilm formation in mycobacteria upon exposure to DTT.					
37081437	3	79	theme	mediated	397:404	arg1	stress					416:421	dithiothreitol (DTT) mediated reductive stress	376:421	dithiothreitol (DTT) mediated reductive stress	376:421	We established earlier that dithiothreitol (DTT) mediated reductive stress induces cellulose-rich biofilm formation in Mtb cultures.					
37081437	0	80	from	formation	53:61	arg1	response					92:99	response	92:99	response to reductive stress	92:119	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	15	81	theme	media	1932:1936	arg1	BSA					1948:1950	media component BSA	1932:1950	media component BSA	1932:1950	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	6	82	theme	non-pathogenic	767:780	arg1	Msm					821:823	Msm	821:823	Msm	821:823	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	6	82	theme	non-pathogenic	767:780	arg1	smegmatis					810:818	non-pathogenic, fast-growing Mycobacterium smegmatis	767:818	non-pathogenic, fast-growing Mycobacterium smegmatis (Msm)	767:824	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	5	83	attach	presence	628:635	arg1	biofilms					653:660	biofilms	653:660	biofilms	653:660	Furthermore, there are only limited tools for monitoring the presence of cellulose in biofilms.					
37081437	5	83	attach	presence	628:635	arg2	cellulose					640:648	cellulose	640:648	cellulose	640:648	Furthermore, there are only limited tools for monitoring the presence of cellulose in biofilms.					
37081437	17	84	used	used	2157:2160	arg2	IMT-CBD-mC					2136:2145	IMT-CBD-mC	2136:2145	IMT-CBD-mC	2136:2145	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	17	84	used	used	2157:2160	arg2	tool					2130:2133	this new tool	2121:2133	this new tool	2121:2133	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37081437	10	85	theme	substances	1178:1187	arg1	composition					1139:1149	the composition	1135:1149	the composition of extracellular polymeric substances of Msm biofilms	1135:1203	Furthermore, we analyzed the composition of extracellular polymeric substances of Msm biofilms.					
37081437	6	86	used	used	754:757	arg2	we					751:752	we	751:752	we	751:752	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	10	87	theme	Msm	1192:1194	arg1	biofilms					1196:1203	Msm biofilms	1192:1203	Msm biofilms	1192:1203	Furthermore, we analyzed the composition of extracellular polymeric substances of Msm biofilms.					
37081437	3	88	theme	cellulose-rich	431:444	arg1	formation					454:462	cellulose-rich biofilm formation	431:462	cellulose-rich biofilm formation	431:462	We established earlier that dithiothreitol (DTT) mediated reductive stress induces cellulose-rich biofilm formation in Mtb cultures.					
37081437	6	89	dep	non-pathogenic	767:780	arg1	fast-growing					783:794	fast-growing	783:794	fast-growing	783:794	RESULTS To decipher the molecular events associated with DTT-induced biofilm formation, we used Mtb and non-pathogenic, fast-growing Mycobacterium smegmatis (Msm).					
37081437	0	90	theme	serum	23:27	arg1	albumin					29:35	bovine serum albumin	16:35	Media component bovine serum albumin	0:35	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	16	91	theme	EPS	2092:2094	arg1	production					2096:2105	EPS production	2092:2105	EPS production	2092:2105	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	5	92	theme	cellulose	640:648	arg1	presence					628:635	the presence	624:635	the presence of cellulose in biofilms	624:660	Furthermore, there are only limited tools for monitoring the presence of cellulose in biofilms.					
37081437	12	93	theme	molecular	1340:1348	arg1	probe					1350:1354	a novel protein-based molecular probe	1318:1354	a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry	1318:1505	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	7	94	theme	biofilm	856:862	arg1	formation					864:872	biofilm formation	856:872	biofilm formation	856:872	We observed that DTT induces biofilm formation in Msm cultures.					
37081437	3	95	theme	Mtb	467:469	arg1	cultures					471:478	Mtb cultures	467:478	Mtb cultures	467:478	We established earlier that dithiothreitol (DTT) mediated reductive stress induces cellulose-rich biofilm formation in Mtb cultures.					
37081437	13	96	theme	high	1566:1569	arg1	affinity					1571:1578	a high affinity	1564:1578	a high affinity for cellulose	1564:1592	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	16	97	theme	cells	2069:2073	arg1	induction					2079:2087	induction	2079:2087	induction of EPS production	2079:2105	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	16	97	theme	cells	2069:2073	arg1	attachment					2045:2054	subsequent attachment	2034:2054	subsequent attachment of bacterial cells	2034:2073	These nucleating foci are critical for subsequent attachment of bacterial cells and induction of EPS production.					
37081437	13	98	theme	probe	1537:1541	arg1	Characterization					1508:1523	Characterization	1508:1523	Characterization of this new probe	1508:1541	Characterization of this new probe revealed that it has a high affinity for cellulose and could be used for visualizing cellulose biosynthesis during the development of Agrobacterium biofilms.					
37081437	2	99	theme	tuberculosis	325:336	arg1	research					338:345	tuberculosis research	325:345	tuberculosis research	325:345	This observation has brought the study of mycobacterial biofilms to the forefront of tuberculosis research.					
37081437	11	100	theme	Mtb	1226:1228	arg1	biofilms					1230:1237	Mtb biofilms	1226:1237	Mtb biofilms	1226:1237	We found that, like Mtb biofilms, Msm biofilms are also rich in polysaccharides and proteins.					
37081437	8	101	from	formation	947:955	arg1	mycobacteria					960:971	mycobacteria	960:971	mycobacteria	960:971	We explored whether media components facilitate biofilm formation in mycobacteria upon exposure to DTT.					
37081437	12	102	theme	novel	1320:1324	arg1	probe					1350:1354	a novel protein-based molecular probe	1318:1354	a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry	1318:1505	We also developed a novel protein-based molecular probe for imaging cellulose by utilizing the cellulose-binding domain of cellulase CenA from Cellulomonas fimi and fusing it to fluorescent reporter mCherry.					
37081437	0	103	dep	component	6:14	arg1	albumin					29:35	bovine serum albumin	16:35	Media component bovine serum albumin	0:35	Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress.					
37081437	15	104	theme	foci	1989:1992	arg1	formation					1965:1973	the formation	1961:1973	the formation of nucleating foci	1961:1992	CONCLUSIONS This study indicates that DTT-mediated reduction of media component BSA leads to the formation of nucleating foci.					
37081437	17	105	from	incorporation	2187:2199	arg1	cells					2210:2214	plant cells	2204:2214	plant cells	2204:2214	Furthermore, this new tool, IMT-CBD-mC, could be used for monitoring cellulose incorporation in plant cells, understanding cellulose biosynthesis dynamics during biofilm formation, etc.					
37019196	5	0	theme	suspending	805:814	arg1	agent					816:820	a suspending agent	803:820	a suspending agent	803:820	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	7	1	dep	in	1232:1233	arg1	situ					1235:1238	situ	1235:1238	situ	1235:1238	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	0	2	with	composites	35:44	arg1	properties					65:74	antimicrobial properties	51:74	antimicrobial properties	51:74	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	2	3	theme	in	385:386	arg1	modification					393:404	in situ modification	385:404	in situ modification of BC	385:410	However, water-insoluble modifiers are usually deposited at the bottom of the medium, therefore cannot be used for in situ modification of BC.					
37019196	6	4	theme	strong	1114:1119	arg1	inhibition					1121:1130	strong inhibition	1114:1130	strong inhibition on Gram-positive bacteria and fungi	1114:1166	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	8	5	dep	in	1331:1332	arg1	situ					1334:1337	situ	1334:1337	situ	1334:1337	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	6	6	from	crystallinity	1056:1068	arg1	bacteria					1149:1156	Gram-positive bacteria	1135:1156	Gram-positive bacteria	1135:1156	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	6	from	crystallinity	1056:1068	arg1	fungi					1162:1166	fungi	1162:1166	fungi	1162:1166	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	6	from	crystallinity	1056:1068	arg1	bacteria					1205:1212	Gram-negative bacteria	1191:1212	Gram-negative bacteria	1191:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	4	7	theme	antibacterial	727:739	arg1	products					741:748	natural antibacterial products	719:748	natural antibacterial products	719:748	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	4	8	theme	Gluconacetobacter	600:616	arg1	xylinus					618:624	not Gluconacetobacter xylinus	596:624	not Gluconacetobacter xylinus	596:624	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	4	8	theme	Gluconacetobacter	600:616	arg1	oryzendophytica					573:587	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	7	9	theme	in	1232:1233	arg1	products					1252:1259	the in situ modified BC products	1228:1259	the in situ modified BC products	1228:1259	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	6	10	from	inhibition	1121:1130	arg1	bacteria					1149:1156	Gram-positive bacteria	1135:1156	Gram-positive bacteria	1135:1156	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	10	from	inhibition	1121:1130	arg1	fungi					1162:1166	fungi	1162:1166	fungi	1162:1166	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	10	from	inhibition	1121:1130	arg1	bacteria					1205:1212	Gram-negative bacteria	1191:1212	Gram-negative bacteria	1191:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	2	11	dep	in	385:386	arg1	situ					388:391	situ	388:391	situ	388:391	However, water-insoluble modifiers are usually deposited at the bottom of the medium, therefore cannot be used for in situ modification of BC.					
37019196	6	12	from	inhibition	1177:1186	arg1	bacteria					1149:1156	Gram-positive bacteria	1135:1156	Gram-positive bacteria	1135:1156	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	12	from	inhibition	1177:1186	arg1	fungi					1162:1166	fungi	1162:1166	fungi	1162:1166	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	12	from	inhibition	1177:1186	arg1	bacteria					1205:1212	Gram-negative bacteria	1191:1212	Gram-negative bacteria	1191:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	5	13	theme	modified	941:948	arg1	products					953:960	the in situ modified BC products	929:960	the in situ modified BC products	929:960	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	6	14	theme	BC	1031:1032	arg1	products					1034:1041	the in situ modified BC products	1010:1041	the in situ modified BC products	1010:1041	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	5	15	theme	xanthan	788:794	arg1	gum					796:798	xanthan gum	788:798	xanthan gum as a suspending agent	788:820	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	5	16	dep	in	933:934	arg1	situ					936:939	situ	936:939	situ	936:939	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	8	17	theme	feasible	1309:1316	arg1	strategy					1318:1325	a feasible strategy	1307:1325	a feasible strategy for in situ modification of BC	1307:1356	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	0	18	theme	specific	114:121	arg1	function-suspension					123:141	the specific function-suspension	110:141	the specific function-suspension containing water-insoluble magnolol	110:177	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	5	19	theme	magnolol	887:894	arg1	extracts					878:885	water-insoluble plant extracts	856:885	water-insoluble plant extracts magnolol in the culture medium	856:916	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	6	20	from	ratio	1104:1108	arg1	bacteria					1149:1156	Gram-positive bacteria	1135:1156	Gram-positive bacteria	1135:1156	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	20	from	ratio	1104:1108	arg1	fungi					1162:1166	fungi	1162:1166	fungi	1162:1166	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	20	from	ratio	1104:1108	arg1	bacteria					1205:1212	Gram-negative bacteria	1191:1212	Gram-negative bacteria	1191:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	7	21	theme	BC	1249:1250	arg1	products					1252:1259	the in situ modified BC products	1228:1259	the in situ modified BC products	1228:1259	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	6	22	theme	properties	987:996	arg1	Characterization					963:978	Characterization	963:978	Characterization of the properties	963:996	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	7	23	theme	modified	1240:1247	arg1	products					1252:1259	the in situ modified BC products	1228:1259	the in situ modified BC products	1228:1259	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	2	24	theme	BC	409:410	arg1	modification					393:404	in situ modification	385:404	in situ modification of BC	385:410	However, water-insoluble modifiers are usually deposited at the bottom of the medium, therefore cannot be used for in situ modification of BC.					
37019196	5	25	theme	water-insoluble	856:870	arg1	extracts					878:885	water-insoluble plant extracts	856:885	water-insoluble plant extracts magnolol in the culture medium	856:916	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	6	26	theme	modified	1022:1029	arg1	products					1034:1041	the in situ modified BC products	1010:1041	the in situ modified BC products	1010:1041	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	4	27	with	products	654:661	arg1	activity					682:689	antibacterial activity	668:689	antibacterial activity	668:689	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	2	28	theme	medium	348:353	arg1	bottom					334:339	the bottom	330:339	the bottom of the medium	330:353	However, water-insoluble modifiers are usually deposited at the bottom of the medium, therefore cannot be used for in situ modification of BC.					
37019196	1	29	theme	Bacterial	226:234	arg1	functionalization					251:267	Bacterial cellulose (BC) functionalization	226:267	Bacterial cellulose (BC) functionalization	226:267	In situ modification is commonly employed for Bacterial cellulose (BC) functionalization.					
37019196	0	30	theme	cellulose	25:33	arg1	composites					35:44	bacterial cellulose composites	15:44	bacterial cellulose composites with antimicrobial properties	15:74	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	0	31	theme	water-insoluble	154:168	arg1	magnolol					170:177	water-insoluble magnolol	154:177	water-insoluble magnolol	154:177	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	1	32	dep	In	180:181	arg1	situ					183:186	situ	183:186	situ	183:186	In situ modification is commonly employed for Bacterial cellulose (BC) functionalization.					
37019196	3	33	theme	modifiers	476:484	arg1	modification					450:461	in situ modification	442:461	in situ modification of insoluble modifiers after suspension by a suspending agent	442:523	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	0	34	theme	bacterial	15:23	arg1	composites					35:44	bacterial cellulose composites	15:44	bacterial cellulose composites with antimicrobial properties	15:74	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	6	35	theme	in	1014:1015	arg1	products					1034:1041	the in situ modified BC products	1010:1041	the in situ modified BC products	1010:1041	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	5	36	theme	BC	950:951	arg1	products					953:960	the in situ modified BC products	929:960	the in situ modified BC products	929:960	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	0	37	contain	containing	143:152	arg2	magnolol					170:177	water-insoluble magnolol	154:177	water-insoluble magnolol	154:177	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	0	37	contain	containing	143:152	arg1	function-suspension					123:141	the specific function-suspension	110:141	the specific function-suspension containing water-insoluble magnolol	110:177	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	4	38	theme	natural	719:725	arg1	products					741:748	natural antibacterial products	719:748	natural antibacterial products	719:748	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	3	39	theme	novel	423:427	arg1	strategy					429:436	a novel strategy	421:436	a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent	421:523	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	6	40	theme	Gram-negative	1191:1203	arg1	bacteria					1205:1212	Gram-negative bacteria	1191:1212	Gram-negative bacteria	1191:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	5	41	theme	experimental	755:766	arg1	results					768:774	The experimental results	751:774	The experimental results	751:774	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	3	42	theme	in	442:443	arg1	modification					450:461	in situ modification	442:461	in situ modification of insoluble modifiers after suspension by a suspending agent	442:523	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	1	43	theme	BC	247:248	arg1	functionalization					251:267	Bacterial cellulose (BC) functionalization	226:267	Bacterial cellulose (BC) functionalization	226:267	In situ modification is commonly employed for Bacterial cellulose (BC) functionalization.					
37019196	0	44	theme	composites	35:44	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification	0:98	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	4	45	theme	BC-producing	543:554	arg1	xylinus					618:624	not Gluconacetobacter xylinus	596:624	not Gluconacetobacter xylinus	596:624	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	4	45	theme	BC-producing	543:554	arg1	oryzendophytica					573:587	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	3	46	dep	in	442:443	arg1	situ					445:448	situ	445:448	situ	445:448	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	5	47	theme	culture	903:909	arg1	medium					911:916	the culture medium	899:916	the culture medium	899:916	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	3	48	theme	insoluble	466:474	arg1	modifiers					476:484	insoluble modifiers	466:484	insoluble modifiers after suspension	466:501	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	5	49	theme	in	933:934	arg1	products					953:960	the in situ modified BC products	929:960	the in situ modified BC products	929:960	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	6	50	theme	swelling	1095:1102	arg1	ratio					1104:1108	significantly increased swelling ratio	1071:1108	significantly increased swelling ratio	1071:1108	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	6	51	theme	weak	1172:1175	arg1	inhibition					1177:1186	weak inhibition	1172:1186	weak inhibition on Gram-negative bacteria	1172:1212	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	0	52	theme	antimicrobial	51:63	arg1	properties					65:74	antimicrobial properties	51:74	antimicrobial properties	51:74	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	4	53	theme	Kosakonia	563:571	arg1	xylinus					618:624	not Gluconacetobacter xylinus	596:624	not Gluconacetobacter xylinus	596:624	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	4	53	theme	Kosakonia	563:571	arg1	oryzendophytica					573:587	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	6	54	dep	in	1014:1015	arg1	situ					1017:1020	situ	1017:1020	situ	1017:1020	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	5	55	theme	plant	872:876	arg1	extracts					878:885	water-insoluble plant extracts	856:885	water-insoluble plant extracts magnolol in the culture medium	856:916	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	5	56	from	magnolol	887:894	arg1	medium					911:916	the culture medium	899:916	the culture medium	899:916	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	3	57	theme	suspending	508:517	arg1	agent					519:523	a suspending agent	506:523	a suspending agent	506:523	Herein, a novel strategy for in situ modification of insoluble modifiers after suspension by a suspending agent was proposed.					
37019196	4	58	theme	strain	556:561	arg1	xylinus					618:624	not Gluconacetobacter xylinus	596:624	not Gluconacetobacter xylinus	596:624	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	4	58	theme	strain	556:561	arg1	oryzendophytica					573:587	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07	539:593	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	8	59	dep	using	1358:1362	arg1	has					1421:1423	has	1421:1423	has significant implications for the biopolymer industry	1421:1476	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	8	59	dep	using	1358:1362	arg1	extend					1393:1398	extend	1393:1398	to extend BC functionality	1390:1415	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	8	60	theme	significant	1425:1435	arg1	implications					1437:1448	significant implications	1425:1448	significant implications for the biopolymer industry	1425:1476	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	8	61	theme	biopolymer	1458:1467	arg1	industry					1469:1476	the biopolymer industry	1454:1476	the biopolymer industry	1454:1476	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	0	62	dep	in	79:80	arg1	situ					82:85	situ	82:85	situ	82:85	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	6	63	theme	increased	1085:1093	arg1	ratio					1104:1108	significantly increased swelling ratio	1071:1108	significantly increased swelling ratio	1071:1108	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	7	64	contain	had	1261:1263	arg1	products					1252:1259	the in situ modified BC products	1228:1259	the in situ modified BC products	1228:1259	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	7	64	contain	had	1261:1263	arg2	toxicity					1268:1275	no toxicity	1265:1275	no toxicity	1265:1275	Furthermore, the in situ modified BC products had no toxicity to cells.					
37019196	8	65	theme	BC	1355:1356	arg1	modification					1339:1350	in situ modification	1331:1350	in situ modification of BC	1331:1356	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	8	66	theme	BC	1400:1401	arg1	functionality					1403:1415	BC functionality	1400:1415	BC functionality	1400:1415	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	0	67	theme	in	79:80	arg1	modification					87:98	in situ modification	79:98	in situ modification	79:98	Fabrication of bacterial cellulose composites with antimicrobial properties by in situ modification utilizing the specific function-suspension containing water-insoluble magnolol.					
37019196	4	68	theme	antibacterial	668:680	arg1	activity					682:689	antibacterial activity	668:689	antibacterial activity	668:689	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	8	69	theme	in	1331:1332	arg1	modification					1339:1350	in situ modification	1331:1350	in situ modification of BC	1331:1356	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37019196	1	70	theme	cellulose	236:244	arg1	functionalization					251:267	Bacterial cellulose (BC) functionalization	226:267	Bacterial cellulose (BC) functionalization	226:267	In situ modification is commonly employed for Bacterial cellulose (BC) functionalization.					
37019196	1	71	theme	In	180:181	arg1	modification					188:199	In situ modification	180:199	In situ modification	180:199	In situ modification is commonly employed for Bacterial cellulose (BC) functionalization.					
37019196	6	72	theme	Gram-positive	1135:1147	arg1	bacteria					1149:1156	Gram-positive bacteria	1135:1156	Gram-positive bacteria	1135:1156	Characterization of the properties showed that the in situ modified BC products have reduced crystallinity, significantly increased swelling ratio and strong inhibition on Gram-positive bacteria and fungi and weak inhibition on Gram-negative bacteria.					
37019196	4	73	theme	BC	651:652	arg1	products					654:661	BC products	651:661	BC products with antibacterial activity	651:689	The BC-producing strain Kosakonia oryzendophytica FY-07, not Gluconacetobacter xylinus, was selected to prepare BC products with antibacterial activity because of its tolerance to natural antibacterial products.					
37019196	2	74	theme	water-insoluble	279:293	arg1	modifiers					295:303	water-insoluble modifiers	279:303	water-insoluble modifiers	279:303	However, water-insoluble modifiers are usually deposited at the bottom of the medium, therefore cannot be used for in situ modification of BC.					
37019196	5	75	from	medium	911:916	arg1	magnolol					887:894	magnolol	887:894	magnolol	887:894	The experimental results showed that xanthan gum as a suspending agent can uniformly and stably disperse water-insoluble plant extracts magnolol in the culture medium to prepare the in situ modified BC products.					
37019196	8	76	theme	water-insoluble	1364:1378	arg1	modifiers					1380:1388	water-insoluble modifiers	1364:1388	water-insoluble modifiers	1364:1388	This study provided a feasible strategy for in situ modification of BC using water-insoluble modifiers to extend BC functionality and has significant implications for the biopolymer industry.					
37005635	4	0	theme	/Titanium	998:1006	arg1	composites					1040:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	6	1	theme	developed	1429:1437	arg1	nanocomposite					1450:1462	the developed SA/TiO2NPs nanocomposite	1425:1462	the developed SA/TiO2NPs nanocomposite	1425:1462	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	2	2	theme	higher	624:629	arg1	growth					631:636	higher growth	624:636	higher growth	624:636	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	4	3	theme	nanoparticles	1016:1028	arg1	composites					1040:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	0	4	with	nanocomposite	91:103	arg1	compatibility					119:131	enhanced compatibility	110:131	enhanced compatibility	110:131	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	0	4	with	nanocomposite	91:103	arg1	efficiency					148:157	anticancer efficiency	137:157	anticancer efficiency	137:157	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	8	5	theme	antitumor	1709:1717	arg1	activity					1719:1726	the antitumor activity	1705:1726	the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites	1705:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	3	6	dep	RESULTS	699:705	arg1	CPT					721:723	CPT	721:723	CPT	721:723	RESULTS Camptothecin (CPT) was purified from the filtrates of A. terreus, and their purity was checked by HPLC, and its chemical structure was verified by LC/MS, regarding to the authentic one.					
37005635	3	6	dep	RESULTS	699:705	arg1	Camptothecin					707:718	Camptothecin	707:718	RESULTS Camptothecin (CPT)	699:724	RESULTS Camptothecin (CPT) was purified from the filtrates of A. terreus, and their purity was checked by HPLC, and its chemical structure was verified by LC/MS, regarding to the authentic one.					
37005635	1	7	theme	prescribed	224:233	arg1	drugs					246:250	the most prescribed anticancer drugs	215:250	the most prescribed anticancer drugs for cancer patients	215:270	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	2	8	theme	growth	583:588	arg1	conditions					590:599	controlled growth conditions	572:599	controlled growth conditions	572:599	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	1	9	theme	drugs	246:250	arg1	drugs					246:250	the most prescribed anticancer drugs	215:250	the most prescribed anticancer drugs for cancer patients	215:270	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	9	theme	drugs	246:250	arg1	one					208:210	one	208:210	one	208:210	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	4	10	theme	anticancer	908:917	arg1	efficiency					919:928	the anticancer efficiency	904:928	the anticancer efficiency of A. terreus CPT	904:946	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	4	11	theme	physicochemical	1062:1076	arg1	properties					1078:1087	their physicochemical properties	1056:1087	their physicochemical properties	1056:1087	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	6	12	theme	spherical	1401:1409	arg1	morphology					1411:1420	the spherical morphology	1397:1420	the spherical morphology of the developed SA/TiO2NPs nanocomposite	1397:1462	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	1	13	theme	cancer	256:261	arg1	patients					263:270	cancer patients	256:270	cancer patients	256:270	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	5	14	from	changes	1252:1258	arg1	bands					1282:1286	the characteristic bands	1263:1286	the characteristic bands of both SA/TiO2 and CPT	1263:1310	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	7	15	theme	SA/TiO2	1593:1599	arg1	nanocomposites					1601:1614	SA/TiO2 nanocomposites	1593:1614	SA/TiO2 nanocomposites	1593:1614	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	1	16	theme	BACKGROUND	168:177	arg1	derivatives					192:202	BACKGROUND Camptothecin derivatives	168:202	BACKGROUND Camptothecin derivatives	168:202	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	7	17	theme	CPT	1584:1586	arg1	binding					1573:1579	binding	1573:1579	binding	1573:1579	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	7	17	theme	CPT	1584:1586	arg1	loading					1561:1567	successful loading	1550:1567	successful loading	1550:1567	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	5	18	theme	spectral	1243:1250	arg1	changes					1252:1258	the spectral changes	1239:1258	the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions	1239:1344	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	0	19	theme	novel	85:89	arg1	nanocomposite					91:103	a novel nanocomposite	83:103	a novel nanocomposite with enhanced compatibility and anticancer efficiency	83:157	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	1	20	theme	water	316:320	arg1	availability					286:297	the availability	282:297	the availability	282:297	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	20	theme	water	316:320	arg1	solubility					322:331	water solubility	316:331	water solubility	316:331	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	20	theme	water	316:320	arg1	efficiency					300:309	efficiency	300:309	efficiency	300:309	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	20	theme	water	316:320	arg1	challenges					347:356	the major challenges	337:356	the major challenges that halt the applicability of this drug	337:397	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	8	21	dep	in	1646:1647	arg1	vivo					1649:1652	vivo	1649:1652	vivo	1649:1652	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	8	22	theme	synthesized	1814:1824	arg1	TiO2NPs					1826:1832	the green synthesized TiO2NPs	1804:1832	the green synthesized TiO2NPs with Aloe vera	1804:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	2	23	theme	scaffold	676:683	arg1	availability					656:667	the availability	652:667	the availability of the scaffold of this drug	652:696	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	2	24	theme	short-life	540:549	arg1	span					551:554	their short-life span	534:554	their short-life span	534:554	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	0	25	theme	anticancer	137:146	arg1	efficiency					148:157	anticancer efficiency	137:157	anticancer efficiency	137:157	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	1	26	theme	drug	394:397	arg1	applicability					372:384	the applicability	368:384	the applicability of this drug	368:397	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	2	27	theme	new	476:478	arg1	avenue					480:485	a new avenue	474:485	a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug	474:696	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	5	28	theme	SA/TiO2	1296:1302	arg1	bands					1282:1286	the characteristic bands	1263:1286	the characteristic bands of both SA/TiO2 and CPT	1263:1310	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	2	29	theme	Biosynthetic	408:419	arg1	potency					421:427	Biosynthetic potency	408:427	METHODS Biosynthetic potency of camptothecin	400:443	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	0	30	theme	Aspergillus	0:10	arg1	dioxide					58:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	0	31	theme	camptothecin-sodium	20:38	arg1	dioxide					58:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	5	32	theme	hydrogen	1139:1146	arg1	interactions					1153:1164	a numerous hydrogen bond interactions	1128:1164	a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites	1128:1221	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	2	33	theme	camptothecin	502:513	arg1	production					515:524	commercial camptothecin production	491:524	commercial camptothecin production	491:524	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	5	34	theme	characteristic	1267:1280	arg1	bands					1282:1286	the characteristic bands	1263:1286	the characteristic bands of both SA/TiO2 and CPT	1263:1310	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	4	35	theme	CPT	944:946	arg1	efficiency					919:928	the anticancer efficiency	904:928	the anticancer efficiency of A. terreus CPT	904:946	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	6	36	theme	electron	1360:1367	arg1	microscopy					1369:1378	Transmission electron microscopy	1347:1378	Transmission electron microscopy analysis	1347:1387	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	1	37	theme	major	341:345	arg1	availability					286:297	the availability	282:297	the availability	282:297	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	37	theme	major	341:345	arg1	solubility					322:331	water solubility	316:331	water solubility	316:331	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	37	theme	major	341:345	arg1	efficiency					300:309	efficiency	300:309	efficiency	300:309	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	1	37	theme	major	341:345	arg1	challenges					347:356	the major challenges	337:356	the major challenges that halt the applicability of this drug	337:397	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	8	38	theme	affordable	1780:1789	arg1	stability					1791:1799	affordable stability	1780:1799	affordable stability of the green synthesized TiO2NPs with Aloe vera	1780:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	8	39	theme	in	1646:1647	arg1	study					1654:1658	The in vivo study	1642:1658	The in vivo study	1642:1658	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	5	40	theme	SA	1183:1184	arg1	chains					1186:1191	SA chains	1183:1191	SA chains	1183:1191	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	5	41	theme	CPT	1308:1310	arg1	bands					1282:1286	the characteristic bands	1263:1286	the characteristic bands of both SA/TiO2 and CPT	1263:1310	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	0	42	dep	Aspergillus	0:10	arg1	terreus					12:18	terreus	12:18	terreus	12:18	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	4	43	theme	dioxide	1008:1014	arg1	composites					1040:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	6	44	theme	SA/TiO2NPs	1439:1448	arg1	nanocomposite					1450:1462	the developed SA/TiO2NPs nanocomposite	1425:1462	the developed SA/TiO2NPs nanocomposite	1425:1462	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	8	45	theme	activity	1719:1726	arg1	improvement					1690:1700	the significant improvement	1674:1700	the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites	1674:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	3	46	theme	terreus	764:770	arg1	filtrates					748:756	the filtrates	744:756	the filtrates of A. terreus	744:770	RESULTS Camptothecin (CPT) was purified from the filtrates of A. terreus, and their purity was checked by HPLC, and its chemical structure was verified by LC/MS, regarding to the authentic one.					
37005635	8	47	theme	CPT	1731:1733	arg1	activity					1719:1726	the antitumor activity	1705:1726	the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites	1705:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	1	48	theme	anticancer	235:244	arg1	drugs					246:250	the most prescribed anticancer drugs	215:250	the most prescribed anticancer drugs for cancer patients	215:270	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	2	49	theme	controlled	572:581	arg1	conditions					590:599	controlled growth conditions	572:599	controlled growth conditions	572:599	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	5	50	from	interactions	1153:1164	arg1	nanocomposites					1208:1221	the SA/TiO2 nanocomposites	1196:1221	the SA/TiO2 nanocomposites	1196:1221	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	6	51	theme	particle	1482:1489	arg1	size ~ 13.3 ± 0.35 nm					1491:1511	the average particle size ~ 13.3 ± 0.35 nm	1470:1511	the average particle size ~ 13.3 ± 0.35 nm	1470:1511	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	8	52	theme	SA/TiO2	1751:1757	arg1	nanocomposites					1759:1772	SA/TiO2 nanocomposites	1751:1772	SA/TiO2 nanocomposites	1751:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	7	53	with	loading	1561:1567	arg1	nanocomposites					1601:1614	SA/TiO2 nanocomposites	1593:1614	SA/TiO2 nanocomposites	1593:1614	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	2	54	theme	conditions	590:599	arg1	feasibility					557:567	feasibility	557:567	feasibility of controlled growth conditions	557:599	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	2	54	theme	conditions	590:599	arg1	span					551:554	their short-life span	534:554	their short-life span	534:554	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	2	54	theme	conditions	590:599	arg1	affordability					606:618	affordability	606:618	affordability	606:618	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	5	55	dep	interactions	1153:1164	arg1	profile					1119:1125	the FT-IR profile	1109:1125	the FT-IR profile	1109:1125	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	5	55	dep	interactions	1153:1164	arg1	changes					1252:1258	the spectral changes	1239:1258	the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions	1239:1344	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	6	56	theme	Transmission	1347:1358	arg1	microscopy					1369:1378	Transmission electron microscopy	1347:1378	Transmission electron microscopy analysis	1347:1387	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	7	57	with	binding	1573:1579	arg1	nanocomposites					1601:1614	SA/TiO2 nanocomposites	1593:1614	SA/TiO2 nanocomposites	1593:1614	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	1	58	theme	Camptothecin	179:190	arg1	derivatives					192:202	BACKGROUND Camptothecin derivatives	168:202	BACKGROUND Camptothecin derivatives	168:202	BACKGROUND Camptothecin derivatives are one of the most prescribed anticancer drugs for cancer patients, however, the availability, efficiency, and water solubility are the major challenges that halt the applicability of this drug.					
37005635	2	59	theme	due	527:529	arg1	production					515:524	commercial camptothecin production	491:524	commercial camptothecin production	491:524	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	5	60	theme	SA/TiO2	1200:1206	arg1	nanocomposites					1208:1221	the SA/TiO2 nanocomposites	1196:1221	the SA/TiO2 nanocomposites	1196:1221	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	0	61	theme	enhanced	110:117	arg1	compatibility					119:131	enhanced compatibility	110:131	enhanced compatibility	110:131	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	8	62	dep	CONCLUSION	1631:1640	arg1	authenticates					1660:1672	authenticates	1660:1672	authenticates	1660:1672	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	7	63	theme	successful	1550:1559	arg1	loading					1561:1567	successful loading	1550:1567	successful loading	1550:1567	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	3	64	theme	chemical	819:826	arg1	structure					828:836	its chemical structure	815:836	its chemical structure	815:836	RESULTS Camptothecin (CPT) was purified from the filtrates of A. terreus, and their purity was checked by HPLC, and its chemical structure was verified by LC/MS, regarding to the authentic one.					
37005635	2	65	dep	METHODS	400:406	arg1	potency					421:427	Biosynthetic potency	408:427	METHODS Biosynthetic potency of camptothecin	400:443	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	8	66	theme	green	1808:1812	arg1	TiO2NPs					1826:1832	the green synthesized TiO2NPs	1804:1832	the green synthesized TiO2NPs with Aloe vera	1804:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	7	67	theme	potential	1539:1547	arg1	results					1523:1529	the results	1519:1529	the results of zeta potential	1519:1547	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	8	68	theme	TiO2NPs	1826:1832	arg1	stability					1791:1799	affordable stability	1780:1799	affordable stability of the green synthesized TiO2NPs with Aloe vera	1780:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	4	69	theme	A.	933:934	arg1	CPT					944:946	A. terreus CPT	933:946	A. terreus CPT	933:946	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	4	70	theme	terreus	936:942	arg1	CPT					944:946	A. terreus CPT	933:946	A. terreus CPT	933:946	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	8	71	theme	Aloe	1839:1842	arg1	vera					1844:1847	Aloe vera	1839:1847	Aloe vera	1839:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	3	72	theme	authentic	878:886	arg1	one					888:890	the authentic one	874:890	the authentic one	874:890	RESULTS Camptothecin (CPT) was purified from the filtrates of A. terreus, and their purity was checked by HPLC, and its chemical structure was verified by LC/MS, regarding to the authentic one.					
37005635	2	73	theme	drug	693:696	arg1	scaffold					676:683	the scaffold	672:683	the scaffold of this drug	672:696	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	0	74	theme	alginate/titanium	40:56	arg1	dioxide					58:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide	0:64	Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo.					
37005635	5	75	theme	numerous	1130:1137	arg1	interactions					1153:1164	a numerous hydrogen bond interactions	1128:1164	a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites	1128:1221	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	5	76	theme	bond	1148:1151	arg1	interactions					1153:1164	a numerous hydrogen bond interactions	1128:1164	a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites	1128:1221	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	7	77	theme	zeta	1534:1537	arg1	potential					1539:1547	zeta potential	1534:1547	zeta potential	1534:1547	From the results of zeta potential, successful loading and binding of CPT with SA/TiO2 nanocomposites were observed.					
37005635	2	78	theme	commercial	491:500	arg1	production					515:524	commercial camptothecin production	491:524	commercial camptothecin production	491:524	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	2	79	theme	camptothecin	432:443	arg1	potency					421:427	Biosynthetic potency	408:427	METHODS Biosynthetic potency of camptothecin	400:443	METHODS Biosynthetic potency of camptothecin by Aspergillus terreus, open a new avenue for commercial camptothecin production, due to their short-life span, feasibility of controlled growth conditions, and affordability for higher growth, that fulfill the availability of the scaffold of this drug.					
37005635	6	80	theme	microscopy	1369:1378	arg1	analysis					1380:1387	Transmission electron microscopy analysis	1347:1387	Transmission electron microscopy analysis	1347:1387	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	5	81	theme	FT-IR	1113:1117	arg1	profile					1119:1125	the FT-IR profile	1109:1125	the FT-IR profile	1109:1125	From the FT-IR profile, a numerous hydrogen bond interactions between TiO2 and SA chains in the SA/TiO2 nanocomposites, in addition to the spectral changes in the characteristic bands of both SA/TiO2 and CPT that confirmed their interactions.					
37005635	6	82	theme	average	1474:1480	arg1	size ~ 13.3 ± 0.35 nm					1491:1511	the average particle size ~ 13.3 ± 0.35 nm	1470:1511	the average particle size ~ 13.3 ± 0.35 nm	1470:1511	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
37005635	4	83	theme	TiO2NPs	1031:1037	arg1	composites					1040:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites	978:1049	To improve the anticancer efficiency of A. terreus CPT, the drug was conjugated with sodium alginate (SA)/Titanium dioxide nanoparticles (TiO2NPs) composites, and their physicochemical properties were assessed.					
37005635	8	84	from	loading	1740:1746	arg1	nanocomposites					1759:1772	SA/TiO2 nanocomposites	1751:1772	SA/TiO2 nanocomposites	1751:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	8	85	theme	significant	1678:1688	arg1	improvement					1690:1700	the significant improvement	1674:1700	the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites	1674:1772	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	8	86	with	TiO2NPs	1826:1832	arg1	vera					1844:1847	Aloe vera	1839:1847	Aloe vera	1839:1847	CONCLUSION The in vivo study authenticates the significant improvement of the antitumor activity of CPT upon loading in SA/TiO2 nanocomposites, with affordable stability of the green synthesized TiO2NPs with Aloe vera leaves extract.					
37005635	6	87	theme	nanocomposite	1450:1462	arg1	morphology					1411:1420	the spherical morphology	1397:1420	the spherical morphology of the developed SA/TiO2NPs nanocomposite	1397:1462	Transmission electron microscopy analysis reveals the spherical morphology of the developed SA/TiO2NPs nanocomposite, with the average particle size ~ 13.3 ± 0.35 nm.					
35900082	11	0	theme	probiotic	2090:2098	arg1	effects					2100:2106	probiotic effects	2090:2106	probiotic effects	2090:2106	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	2	1	from	inflammation	420:431	arg1	UC					436:437	UC	436:437	UC	436:437	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	12	2	theme	altered	2348:2354	arg1	responses					2367:2375	altered gut immune responses	2348:2375	altered gut immune responses	2348:2375	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	11	3	dep	Bacillus	2038:2045	arg1	coagulans					2047:2055	coagulans	2047:2055	coagulans	2047:2055	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	3	4	theme	intestinal	517:526	arg1	diseases					528:535	intestinal diseases	517:535	intestinal diseases	517:535	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	1	5	theme	system	257:262	arg1	disorders					264:272	immune system disorders	250:272	immune system disorders	250:272	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	11	6	theme	stability	2076:2084	arg1	advantages					2062:2071	advantages	2062:2071	advantages of stability and probiotic effects	2062:2106	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	12	7	theme	immune	2360:2365	arg1	responses					2367:2375	altered gut immune responses	2348:2375	altered gut immune responses	2348:2375	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	3	8	theme	industrial	562:571	arg1	production					637:646	lactic acid production	625:646	lactic acid production	625:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	8	theme	industrial	562:571	arg1	properties					587:596	its favorable industrial and probiotic properties	548:596	its favorable industrial and probiotic properties	548:596	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	8	theme	industrial	562:571	arg1	sporulation					609:619	sporulation	609:619	sporulation	609:619	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	10	9	theme	prebiotic	1894:1902	arg1	IMPORTANCE					1869:1878	IMPORTANCE	1869:1878	IMPORTANCE Probiotic and prebiotic	1869:1902	IMPORTANCE Probiotic and prebiotic are believed to be useful in alleviating the inflammatory, thereby resolving or preventing the severity of UC.					
35900082	5	10	theme	B.	861:862	arg1	COSs					892:895	prebiotic COSs	882:895	prebiotic COSs	882:895	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	10	theme	B.	861:862	arg1	synbiotic					904:912	the synbiotic	900:912	the synbiotic (the spores + COSs)	900:932	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	10	theme	B.	861:862	arg1	spores					874:879	B. coagulans spores	861:879	B. coagulans spores	861:879	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	9	11	theme	inflammatory	1671:1682	arg1	status					1684:1689	the overall inflammatory status	1659:1689	the overall inflammatory status of the experimental UC model	1659:1718	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	5	12	contain	had	934:936	arg2	effect					961:966	a significant positive effect	938:966	a significant positive effect	938:966	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	12	contain	had	934:936	arg1	Supplementation					842:856	Supplementation	842:856	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs)	842:932	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	13	theme	spores	874:879	arg1	Supplementation					842:856	Supplementation	842:856	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs)	842:932	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	14	14	with	combination	2722:2732	arg1	COSs					2739:2742	COSs	2739:2742	COSs	2739:2742	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	7	15	theme	barrier	1377:1383	arg1	recovery					1350:1357	recovery	1350:1357	recovery of the intestinal barrier	1350:1383	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	13	16	theme	probiotic	2462:2470	arg1	Akkermansia					2490:2500	Akkermansia	2490:2500	Akkermansia	2490:2500	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	13	16	theme	probiotic	2462:2470	arg1	bacteria					2472:2479	probiotic bacteria	2462:2479	probiotic bacteria	2462:2479	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	13	16	theme	probiotic	2462:2470	arg1	Ruminococcaceae					2506:2520	Ruminococcaceae	2506:2520	Ruminococcaceae	2506:2520	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	3	17	theme	probiotic	577:585	arg1	production					637:646	lactic acid production	625:646	lactic acid production	625:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	17	theme	probiotic	577:585	arg1	properties					587:596	its favorable industrial and probiotic properties	548:596	its favorable industrial and probiotic properties	548:596	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	17	theme	probiotic	577:585	arg1	sporulation					609:619	sporulation	609:619	sporulation	609:619	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	9	18	theme	experimental	1698:1709	arg1	model					1714:1718	the experimental UC model	1694:1718	the experimental UC model	1694:1718	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	3	19	theme	lactic	625:630	arg1	production					637:646	lactic acid production	625:646	lactic acid production	625:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	9	20	theme	model	1714:1718	arg1	status					1684:1689	the overall inflammatory status	1659:1689	the overall inflammatory status of the experimental UC model	1659:1718	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	14	21	theme	therapeutic	2633:2643	arg1	strategies					2660:2669	therapeutic and preventive strategies	2633:2669	strategies	2660:2669	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	4	22	theme	spores	726:731	arg1	effects					691:697	the treatment effects	677:697	the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice	677:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	9	23	dep	levels	1861:1866	arg1	IL-4					1843:1846	IL-4	1843:1846	IL-4	1843:1846	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	9	23	dep	levels	1861:1866	arg1	levels					1861:1866	, colon length, IL-4 and Occludin levels	1827:1866	levels	1861:1866	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	9	23	dep	levels	1861:1866	arg1	length					1835:1840	colon length	1829:1840	colon length	1829:1840	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	9	23	dep	levels	1861:1866	arg1	Occludin					1852:1859	Occludin	1852:1859	Occludin	1852:1859	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	1	24	theme	Ulcerative	135:144	arg1	colitis					146:152	Ulcerative colitis	135:152	Ulcerative colitis (UC)	135:157	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	1	24	theme	Ulcerative	135:144	arg1	disorders					184:192	chronic inflammatory disorders	163:192	chronic inflammatory disorders	163:192	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	1	24	theme	Ulcerative	135:144	arg1	UC					155:156	UC	155:156	UC	155:156	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	8	25	theme	microbiota	1454:1463	arg1	composition					1435:1445	the composition	1431:1445	the composition of gut microbiota	1431:1463	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	6	26	theme	disease	991:997	arg1	index					1008:1012	The disease activity index	987:1012	The disease activity index	987:1012	The disease activity index and histological damage score were significantly reduced after these supplementations.					
35900082	9	27	theme	better	1733:1738	arg1	effect					1750:1755	a better treatment effect	1731:1755	a better treatment effect than B. coagulans or COSs	1731:1781	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	7	28	theme	mucin	1323:1327	arg1	protein					1329:1335	mucin protein	1323:1335	mucin protein	1323:1335	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	5	29	theme	prebiotic	882:890	arg1	COSs					892:895	prebiotic COSs	882:895	prebiotic COSs	882:895	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	29	theme	prebiotic	882:890	arg1	spores					874:879	B. coagulans spores	861:879	B. coagulans spores	861:879	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	10	30	theme	UC	2011:2012	arg1	severity					1999:2006	the severity	1995:2006	the severity of UC	1995:2012	IMPORTANCE Probiotic and prebiotic are believed to be useful in alleviating the inflammatory, thereby resolving or preventing the severity of UC.					
35900082	12	31	theme	DSS-induced	2294:2304	arg1	colitis					2306:2312	DSS-induced colitis	2294:2312	DSS-induced colitis	2294:2312	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	1	32	theme	chronic	163:169	arg1	colitis					146:152	Ulcerative colitis	135:152	Ulcerative colitis (UC)	135:157	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	1	32	theme	chronic	163:169	arg1	disorders					184:192	chronic inflammatory disorders	163:192	chronic inflammatory disorders	163:192	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	8	33	theme	short-chain	1495:1505	arg1	SCFAs					1520:1524	SCFAs	1520:1524	SCFAs	1520:1524	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	8	33	theme	short-chain	1495:1505	arg1	acids					1513:1517	short-chain fatty acids	1495:1517	short-chain fatty acids (SCFAs)	1495:1525	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	0	34	theme	DSS-Induced	106:116	arg1	Colitis					118:124	the DSS-Induced Colitis	102:124	the DSS-Induced Colitis in Mice	102:132	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	4	35	dep	B.	706:707	arg1	coagulans					709:717	coagulans	709:717	coagulans	709:717	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	8	36	theme	acids	1513:1517	arg1	production					1481:1490	the production	1477:1490	the production of short-chain fatty acids (SCFAs)	1477:1525	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	5	37	theme	positive	952:959	arg1	effect					961:966	a significant positive effect	938:966	a significant positive effect	938:966	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	12	38	theme	chitooligosaccharides	2236:2256	arg1	administration					2197:2210	administration	2197:2210	administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic	2197:2281	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	0	39	theme	Bacillus	0:7	arg1	coagulans					9:17	Bacillus coagulans	0:17	Bacillus coagulans in Combination with Chitooligosaccharides	0:59	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	1	40	theme	intestinal	278:287	arg1	dysbiosis					300:308	intestinal microbiota dysbiosis	278:308	intestinal microbiota dysbiosis	278:308	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	7	41	theme	junction	1301:1308	arg1	proteins					1310:1317	tight junction proteins	1295:1317	tight junction proteins	1295:1317	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	13	42	theme	gut	2578:2580	arg1	health					2582:2587	gut health	2578:2587	gut health	2578:2587	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	13	43	theme	synbiotic	2406:2414	arg1	effect					2392:2397	The treatment effect	2378:2397	The treatment effect of the synbiotic	2378:2414	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	6	44	theme	histological	1018:1029	arg1	score					1038:1042	histological damage score	1018:1042	histological damage score	1018:1042	The disease activity index and histological damage score were significantly reduced after these supplementations.					
35900082	13	45	dep	Akkermansia	2490:2500	arg1	species					2522:2528	species	2522:2528	species	2522:2528	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	14	46	theme	lactic	2698:2703	arg1	bacteria					2710:2717	spore-forming lactic acid bacteria	2684:2717	spore-forming lactic acid bacteria	2684:2717	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	11	47	theme	UC	2157:2158	arg1	treatment					2160:2168	UC treatment	2157:2168	UC treatment	2157:2168	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	8	48	theme	SCFA-producing	1550:1563	arg1	bacteria					1565:1572	SCFA-producing bacteria	1550:1572	SCFA-producing bacteria	1550:1572	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	8	48	theme	SCFA-producing	1550:1563	arg1	Akkermansia					1583:1593	Akkermansia	1583:1593	Akkermansia	1583:1593	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	8	48	theme	SCFA-producing	1550:1563	arg1	species					1612:1618	Ruminococcus species	1599:1618	Ruminococcus species	1599:1618	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	3	49	theme	probiotic	494:502	arg1	coagulans					449:457	Bacillus coagulans	440:457	Bacillus coagulans	440:457	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	49	theme	probiotic	494:502	arg1	potential					484:492	a potential probiotic	482:502	a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production	482:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	13	50	theme	treatment	2382:2390	arg1	effect					2392:2397	The treatment effect	2378:2397	The treatment effect of the synbiotic	2378:2414	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	2	51	theme	probiotics	341:350	arg1	Synbiotic					311:319	Synbiotic	311:319	Synbiotic	311:319	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	2	51	theme	probiotics	341:350	arg1	combination					326:336	the combination	322:336	the combination of probiotics and prebiotics	322:365	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	1	52	theme	intestinal	218:227	arg1	dysfunction					237:247	intestinal barrier dysfunction	218:247	intestinal barrier dysfunction	218:247	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	12	53	dep	B.	2215:2216	arg1	coagulans					2218:2226	coagulans	2218:2226	coagulans	2218:2226	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	9	54	theme	colon	1829:1833	arg1	levels					1861:1866	, colon length, IL-4 and Occludin levels	1827:1866	levels	1861:1866	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	9	54	theme	colon	1829:1833	arg1	length					1835:1840	colon length	1829:1840	colon length	1829:1840	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	4	55	theme	sulfate	812:818	arg1	DSS					828:830	DSS	828:830	DSS	828:830	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	4	55	theme	sulfate	812:818	arg1	sodium					820:825	dextran sulfate sodium	804:825	dextran sulfate sodium (DSS) in mice	804:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	14	56	theme	preventive	2649:2658	arg1	strategies					2660:2669	therapeutic and preventive strategies	2633:2669	strategies	2660:2669	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	7	57	theme	DSS	1113:1115	arg1	group					1117:1121	DSS group	1113:1121	DSS group	1113:1121	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	1	58	theme	immune	250:255	arg1	disorders					264:272	immune system disorders	250:272	immune system disorders	250:272	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	11	59	theme	effects	2100:2106	arg1	advantages					2062:2071	advantages	2062:2071	advantages of stability and probiotic effects	2062:2106	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	7	60	theme	C-reactive	1219:1228	arg1	protein					1230:1236	C-reactive protein	1219:1236	C-reactive protein (CRP) levels	1219:1249	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	60	theme	C-reactive	1219:1228	arg1	CRP					1239:1241	CRP	1239:1241	CRP	1239:1241	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	3	61	theme	favorable	552:560	arg1	production					637:646	lactic acid production	625:646	lactic acid production	625:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	61	theme	favorable	552:560	arg1	properties					587:596	its favorable industrial and probiotic properties	548:596	its favorable industrial and probiotic properties	548:596	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	3	61	theme	favorable	552:560	arg1	sporulation					609:619	sporulation	609:619	sporulation	609:619	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	12	62	theme	gut	2356:2358	arg1	responses					2367:2375	altered gut immune responses	2348:2375	altered gut immune responses	2348:2375	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	2	63	theme	prebiotics	356:365	arg1	Synbiotic					311:319	Synbiotic	311:319	Synbiotic	311:319	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	2	63	theme	prebiotics	356:365	arg1	combination					326:336	the combination	322:336	the combination of probiotics and prebiotics	322:365	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	1	64	theme	inflammatory	171:182	arg1	colitis					146:152	Ulcerative colitis	135:152	Ulcerative colitis (UC)	135:157	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	1	64	theme	inflammatory	171:182	arg1	disorders					184:192	chronic inflammatory disorders	163:192	chronic inflammatory disorders	163:192	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	9	65	theme	overall	1663:1669	arg1	status					1684:1689	the overall inflammatory status	1659:1689	the overall inflammatory status of the experimental UC model	1659:1718	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	5	66	theme	coagulans	864:872	arg1	COSs					892:895	prebiotic COSs	882:895	prebiotic COSs	882:895	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	66	theme	coagulans	864:872	arg1	synbiotic					904:912	the synbiotic	900:912	the synbiotic (the spores + COSs)	900:932	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	66	theme	coagulans	864:872	arg1	spores					874:879	B. coagulans spores	861:879	B. coagulans spores	861:879	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	8	67	theme	fatty	1507:1511	arg1	SCFAs					1520:1524	SCFAs	1520:1524	SCFAs	1520:1524	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	8	67	theme	fatty	1507:1511	arg1	acids					1513:1517	short-chain fatty acids	1495:1517	short-chain fatty acids (SCFAs)	1495:1525	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	4	68	theme	treatment	681:689	arg1	effects					691:697	the treatment effects	677:697	the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice	677:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	11	69	theme	Bacillus	2038:2045	arg1	bacteria					2029:2036	Spore-forming bacteria	2015:2036	Spore-forming bacteria Bacillus coagulans	2015:2055	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	13	70	theme	bacteria	2472:2479	arg1	enrichment					2448:2457	the enrichment	2444:2457	the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health	2444:2587	The treatment effect of the synbiotic is inferred to be relied on the enrichment of probiotic bacteria, such as Akkermansia and Ruminococcaceae species, which are reported to be crucial important for gut health.					
35900082	11	71	theme	Spore-forming	2015:2027	arg1	bacteria					2029:2036	Spore-forming bacteria	2015:2036	Spore-forming bacteria Bacillus coagulans	2015:2055	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	8	72	theme	gut	1450:1452	arg1	microbiota					1454:1463	gut microbiota	1450:1463	gut microbiota	1450:1463	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	7	73	theme	intestinal	1366:1375	arg1	barrier					1377:1383	the intestinal barrier	1362:1383	the intestinal barrier	1362:1383	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	12	74	theme	synbiotic	2273:2281	arg1	administration					2197:2210	administration	2197:2210	administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic	2197:2281	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	4	75	theme	FCYS01	719:724	arg1	spores					726:731	the B. coagulans FCYS01 spores	702:731	the B. coagulans FCYS01 spores	702:731	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	4	76	from	sodium	820:825	arg1	mice					836:839	mice	836:839	mice	836:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	6	77	theme	activity	999:1006	arg1	index					1008:1012	The disease activity index	987:1012	The disease activity index	987:1012	The disease activity index and histological damage score were significantly reduced after these supplementations.					
35900082	0	78	from	Colitis	118:124	arg1	Mice					129:132	Mice	129:132	Mice	129:132	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	3	79	theme	acid	632:635	arg1	production					637:646	lactic acid production	625:646	lactic acid production	625:646	Bacillus coagulans has been recognized as a potential probiotic for treating intestinal diseases because of its favorable industrial and probiotic properties, including sporulation and lactic acid production.					
35900082	9	80	theme	treatment	1740:1748	arg1	effect					1750:1755	a better treatment effect	1731:1755	a better treatment effect than B. coagulans or COSs	1731:1781	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	7	81	theme	protein	1329:1335	arg1	expressions					1280:1290	expressions	1280:1290	expressions of tight junction proteins and mucin protein	1280:1335	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	0	82	from	coagulans	9:17	arg1	Combination					22:32	Combination	22:32	Combination with Chitooligosaccharides	22:59	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	4	83	theme	B.	706:707	arg1	spores					726:731	the B. coagulans FCYS01 spores	702:731	the B. coagulans FCYS01 spores	702:731	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	9	84	dep	showed	1724:1729	arg1	did					1783:1785	did	1783:1785	showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels	1724:1866	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	7	85	dep	cytokines	1180:1188	arg1	IL-6					1196:1199	IL-6	1196:1199	IL-6	1196:1199	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	85	dep	cytokines	1180:1188	arg1	IL-8					1202:1205	IL-8	1202:1205	IL-8	1202:1205	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	85	dep	cytokines	1180:1188	arg1	cytokines					1180:1188	the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels	1176:1249	the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels	1176:1249	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	85	dep	cytokines	1180:1188	arg1	IL-10					1208:1212	IL-10	1208:1212	IL-10	1208:1212	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	85	dep	cytokines	1180:1188	arg1	IL-4					1190:1193	IL-4	1190:1193	IL-4	1190:1193	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	7	85	dep	cytokines	1180:1188	arg1	levels					1244:1249	C-reactive protein (CRP) levels	1219:1249	C-reactive protein (CRP) levels	1219:1249	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	5	86	theme	significant	940:950	arg1	effect					961:966	a significant positive effect	938:966	a significant positive effect	938:966	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	7	87	theme	proteins	1310:1317	arg1	expressions					1280:1290	expressions	1280:1290	expressions of tight junction proteins and mucin protein	1280:1335	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	5	88	dep	synbiotic	904:912	arg1	COSs					928:931	COSs	928:931	COSs	928:931	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	5	88	dep	synbiotic	904:912	arg1	spores					919:924	the spores	915:924	the spores	915:924	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	2	89	theme	pragmatic	387:395	arg1	approach					397:404	a pragmatic approach	385:404	a pragmatic approach	385:404	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	2	89	theme	pragmatic	387:395	arg1	Synbiotic					311:319	Synbiotic	311:319	Synbiotic	311:319	Synbiotic, the combination of probiotics and prebiotics, is thought to be a pragmatic approach in mitigating inflammation in UC.					
35900082	4	90	from	chitooligosaccharides	753:773	arg1	UC					785:786	UC	785:786	UC generated using dextran sulfate sodium (DSS) in mice	785:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	12	91	theme	spores	2228:2233	arg1	administration					2197:2210	administration	2197:2210	administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic	2197:2281	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	7	92	theme	tight	1295:1299	arg1	proteins					1310:1317	tight junction proteins	1295:1317	tight junction proteins	1295:1317	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	1	93	theme	microbiota	289:298	arg1	dysbiosis					300:308	intestinal microbiota dysbiosis	278:308	intestinal microbiota dysbiosis	278:308	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	6	94	theme	damage	1031:1036	arg1	score					1038:1042	histological damage score	1018:1042	histological damage score	1018:1042	The disease activity index and histological damage score were significantly reduced after these supplementations.					
35900082	11	95	theme	important	2132:2140	arg1	probiotics					2142:2151	the important probiotics	2128:2151	the important probiotics for UC treatment	2128:2168	Spore-forming bacteria Bacillus coagulans show advantages of stability and probiotic effects, being suggested as the important probiotics for UC treatment.					
35900082	14	96	theme	strategies	2660:2669	arg1	development					2618:2628	the development	2614:2628	the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs	2614:2742	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	14	97	theme	acid	2705:2708	arg1	bacteria					2710:2717	spore-forming lactic acid bacteria	2684:2717	spore-forming lactic acid bacteria	2684:2717	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	8	98	theme	bacteria	1565:1572	arg1	enrichment					1536:1545	enrichment	1536:1545	enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species	1536:1618	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	0	99	with	Combination	22:32	arg1	Chitooligosaccharides					39:59	Chitooligosaccharides	39:59	Chitooligosaccharides	39:59	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	0	100	theme	Gut	71:73	arg1	Microbiota					75:84	Gut Microbiota	71:84	Gut Microbiota	71:84	Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.					
35900082	14	101	theme	spore-forming	2684:2696	arg1	bacteria					2710:2717	spore-forming lactic acid bacteria	2684:2717	spore-forming lactic acid bacteria	2684:2717	Our findings facilitate the development of therapeutic and preventive strategies for UC using spore-forming lactic acid bacteria in combination with COSs.					
35900082	9	102	theme	UC	1711:1712	arg1	model					1714:1718	the experimental UC model	1694:1718	the experimental UC model	1694:1718	In summary, the synbiotic ameliorated the overall inflammatory status of the experimental UC model and showed a better treatment effect than B. coagulans or COSs did alone as revealed by the markers such as, colon length, IL-4 and Occludin levels.					
35900082	12	103	theme	B.	2215:2216	arg1	spores					2228:2233	B. coagulans spores	2215:2233	B. coagulans spores	2215:2233	Here, we demonstrate that administration of B. coagulans spores, chitooligosaccharides (COSs), or the synbiotic attenuates DSS-induced colitis and significantly correlates with altered gut immune responses.					
35900082	1	104	theme	barrier	229:235	arg1	dysfunction					237:247	intestinal barrier dysfunction	218:247	intestinal barrier dysfunction	218:247	Ulcerative colitis (UC) are chronic inflammatory disorders, which may be caused by intestinal barrier dysfunction, immune system disorders and intestinal microbiota dysbiosis.					
35900082	5	105	theme	DSS-induced	971:981	arg1	UC					983:984	DSS-induced UC	971:984	DSS-induced UC	971:984	Supplementation of B. coagulans spores, prebiotic COSs or the synbiotic (the spores + COSs) had a significant positive effect on DSS-induced UC.					
35900082	7	106	theme	protein	1230:1236	arg1	levels					1244:1249	C-reactive protein (CRP) levels	1219:1249	C-reactive protein (CRP) levels	1219:1249	Compared to DSS group, these supplementations also significantly modulated the cytokines IL-4, IL-6, IL-8, IL-10, and C-reactive protein (CRP) levels and significantly maintained expressions of tight junction proteins and mucin protein and promotes recovery of the intestinal barrier.					
35900082	8	107	theme	Ruminococcus	1599:1610	arg1	species					1612:1618	Ruminococcus species	1599:1618	Ruminococcus species	1599:1618	In addition, these supplementations regulate the composition of gut microbiota and improve the production of short-chain fatty acids (SCFAs), through enrichment of SCFA-producing bacteria, such as Akkermansia and Ruminococcus species.					
35900082	10	108	theme	Probiotic	1880:1888	arg1	IMPORTANCE					1869:1878	IMPORTANCE	1869:1878	IMPORTANCE Probiotic and prebiotic	1869:1902	IMPORTANCE Probiotic and prebiotic are believed to be useful in alleviating the inflammatory, thereby resolving or preventing the severity of UC.					
35900082	4	109	theme	dextran	804:810	arg1	DSS					828:830	DSS	828:830	DSS	828:830	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
35900082	4	109	theme	dextran	804:810	arg1	sodium					820:825	dextran sulfate sodium	804:825	dextran sulfate sodium (DSS) in mice	804:839	In this study, we evaluated the treatment effects of the B. coagulans FCYS01 spores with or without the chitooligosaccharides (COSs) on UC generated using dextran sulfate sodium (DSS) in mice.					
37192712	6	0	theme	essential	1048:1056	arg1	oil					1058:1060	citral essential oil	1041:1060	citral essential oil onto SPI nanocomposite film	1041:1088	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	6	1	theme	various	1148:1154	arg1	groups					1165:1170	various phenolic groups	1148:1170	various phenolic groups	1148:1170	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	0	2	theme	-based	169:174	arg1	films					186:190	soy protein isolate (SPI)-based composite films	144:190	soy protein isolate (SPI)-based composite films	144:190	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	3	3	theme	groups	513:518	arg1	presence					495:502	The presence	491:502	The presence of amino groups in APTES	491:527	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	4	4	theme	cross-linker	626:637	arg1	incorporation					595:607	The incorporation	591:607	The incorporation of a citric acid cross-linker	591:637	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	0	5	theme	films	186:190	arg1	mechanical					59:68	mechanical	59:68	mechanical	59:68	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	7	6	theme	nanocellulose	1370:1382	arg1	incorporation					1334:1346	incorporation	1334:1346	incorporation of 1 % APTES-modified nanocellulose	1334:1382	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	5	7	theme	properties	829:838	arg1	study					793:797	the study	789:797	the study of the mechanical and thermal properties and water resistance of the film	789:871	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	9	8	theme	packing	1653:1659	arg1	grapes					1667:1672	packing black grapes	1653:1672	packing black grapes	1653:1672	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	7	9	theme	%	1353:1353	arg1	nanocellulose					1370:1382	1 % APTES-modified nanocellulose	1351:1382	1 % APTES-modified nanocellulose	1351:1382	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	7	10	contain	containing	1265:1274	arg1	nanocellulose					1251:1263	silane-modified nanocellulose	1235:1263	silane-modified nanocellulose containing film	1235:1279	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	7	10	contain	containing	1265:1274	arg2	film					1276:1279	film	1276:1279	film	1276:1279	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	4	11	theme	citric	614:619	arg1	cross-linker					626:637	a citric acid cross-linker	612:637	a citric acid cross-linker	612:637	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	3	12	theme	cross-linked	549:560	arg1	structures					562:571	cross-linked structures	549:571	cross-linked structures	549:571	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	5	13	theme	film	868:871	arg1	resistance					850:859	water resistance	844:859	water resistance	844:859	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	5	13	theme	film	868:871	arg1	properties					829:838	properties	829:838	properties	829:838	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	4	14	theme	surface	695:701	arg1	smoothness					703:712	the surface smoothness	691:712	the surface smoothness of the film	691:724	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	2	15	theme	citric	465:470	arg1	cross-linker					477:488	citric acid cross-linker	465:488	citric acid cross-linker	465:488	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	6	16	theme	groups	1165:1170	arg1	presence					1136:1143	the presence	1132:1143	the presence of various phenolic groups	1132:1170	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	5	17	theme	water	844:848	arg1	resistance					850:859	water resistance	844:859	water resistance	844:859	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	8	18	theme	silylated	1451:1459	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	4	19	theme	productive	675:684	arg1	process					662:668	the cross-linking process	644:668	the cross-linking process more productive	644:684	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	0	20	theme	water	71:75	arg1	resistance					77:86	water resistance	71:86	water resistance	71:86	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	0	21	from	Influence	0:8	arg1	properties					130:139	antibacterial properties	116:139	antibacterial properties	116:139	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	0	21	from	Influence	0:8	arg1	thermal					89:95	thermal	89:95	thermal	89:95	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	0	21	from	Influence	0:8	arg1	mechanical					59:68	mechanical	59:68	mechanical	59:68	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	0	21	from	Influence	0:8	arg1	resistance					77:86	water resistance	71:86	water resistance	71:86	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	0	21	from	Influence	0:8	arg1	morphological					98:110	morphological	98:110	morphological	98:110	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	2	22	theme	cross-linker	477:488	arg1	presence					453:460	the presence	449:460	the presence of citric acid cross-linker	449:488	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	8	23	theme	protein	1492:1498	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	2	24	theme	APTES	366:370	arg1	nanocellulose					397:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	7	25	theme	%	1303:1303	arg1	%					1315:1315	~119 % and ~ 112 %	1298:1315	~119 % and ~ 112 %	1298:1315	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	2	26	theme	3-aminopropyltriethoxysilane	336:363	arg1	nanocellulose					397:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	1	27	theme	mechanical	241:250	arg1	properties					273:282	the mechanical and water-resistance properties	237:282	the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm	237:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	7	28	dep	Strength	1203:1210	arg1	The					1191:1193	The	1191:1193	The	1191:1193	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	4	29	theme	film	721:724	arg1	smoothness					703:712	the surface smoothness	691:712	the surface smoothness of the film	691:724	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	2	30	theme	modified	388:395	arg1	nanocellulose					397:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	0	31	theme	silylated	13:21	arg1	reinforcement					38:50	silylated nano cellulose reinforcement	13:50	silylated nano cellulose reinforcement	13:50	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	1	32	theme	water-resistance	256:271	arg1	properties					273:282	the mechanical and water-resistance properties	237:282	the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm	237:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	8	33	theme	bio	1520:1522	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	2	34	theme	coupling	373:380	arg1	nanocellulose					397:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	0	35	theme	cellulose	28:36	arg1	reinforcement					38:50	silylated nano cellulose reinforcement	13:50	silylated nano cellulose reinforcement	13:50	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	2	36	theme	SPI	435:437	arg1	matrix					439:444	the SPI matrix	431:444	the SPI matrix	431:444	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	1	37	theme	protein	291:297	arg1	biofilm					313:319	soy protein isolate (SPI) biofilm	287:319	soy protein isolate (SPI) biofilm	287:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	7	38	theme	silane-modified	1235:1249	arg1	nanocellulose					1251:1263	silane-modified nanocellulose	1235:1263	silane-modified nanocellulose containing film	1235:1279	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	8	39	theme	packaging	1548:1556	arg1	applications					1558:1569	packaging applications	1548:1569	packaging applications	1548:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	4	40	theme	Electron	754:761	arg1	Microscope					763:772	a Scanning Electron Microscope	743:772	a Scanning Electron Microscope (FE-SEM)	743:781	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	4	40	theme	Electron	754:761	arg1	FE-SEM					775:780	FE-SEM	775:780	FE-SEM	775:780	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	6	41	theme	SPI	1067:1069	arg1	film					1085:1088	SPI nanocomposite film	1067:1088	SPI nanocomposite film	1067:1088	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	1	42	theme	research	209:216	arg1	work					218:221	this research work	204:221	this research work	204:221	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	7	43	theme	Young	1216:1220	arg1	Modulus					1224:1230	Young's Modulus	1216:1230	Young's Modulus	1216:1230	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	6	44	theme	citral	1041:1046	arg1	oil					1058:1060	citral essential oil	1041:1060	citral essential oil onto SPI nanocomposite film	1041:1088	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	0	45	theme	composite	176:184	arg1	films					186:190	soy protein isolate (SPI)-based composite films	144:190	soy protein isolate (SPI)-based composite films	144:190	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	3	46	theme	amino	507:511	arg1	groups					513:518	amino groups	507:518	amino groups	507:518	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	9	47	theme	application	1619:1629	arg1	one					1608:1610	one	1608:1610	one	1608:1610	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	9	47	theme	application	1619:1629	arg1	application					1619:1629	the application	1615:1629	the application as wrapping films for packing black grapes	1615:1672	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	9	47	theme	application	1619:1629	arg1	example					1578:1584	an example	1575:1584	an example	1575:1584	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	5	48	theme	mechanical	806:815	arg1	properties					829:838	properties	829:838	properties	829:838	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	9	49	theme	wrapping	1634:1641	arg1	films					1643:1647	wrapping films	1634:1647	wrapping films for packing black grapes	1634:1672	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	4	50	theme	acid	621:624	arg1	cross-linker					626:637	a citric acid cross-linker	612:637	a citric acid cross-linker	612:637	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	5	51	theme	thermal	821:827	arg1	properties					829:838	properties	829:838	properties	829:838	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	6	52	theme	due	1125:1127	arg1	properties					1114:1123	antimicrobial properties	1100:1123	antimicrobial properties due to the presence of various phenolic groups	1100:1170	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	0	53	theme	antibacterial	116:128	arg1	properties					130:139	antibacterial properties	116:139	antibacterial properties	116:139	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	9	54	theme	black	1661:1665	arg1	grapes					1667:1672	packing black grapes	1653:1672	packing black grapes	1653:1672	As an example, we have demonstrated one of the application as wrapping films for packing black grapes.					
37192712	6	55	theme	antimicrobial	1100:1112	arg1	properties					1114:1123	antimicrobial properties	1100:1123	antimicrobial properties due to the presence of various phenolic groups	1100:1170	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	7	56	theme	1 	1351:1352	arg1	%					1353:1353	%	1353:1353	%	1353:1353	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	8	57	theme	reinforcing	1476:1486	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	8	58	theme	effective	1433:1441	arg1	way					1443:1445	an effective way	1430:1445	an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1430:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	6	59	theme	citral	1179:1184	arg1	oil					1186:1188	the citral oil	1175:1188	the citral oil	1175:1188	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	5	60	theme	non-modified	998:1009	arg1	one					1011:1013	the non-modified one	994:1013	the non-modified one	994:1013	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	3	61	theme	soy	578:580	arg1	protein					582:588	soy protein	578:588	soy protein	578:588	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	8	62	theme	nano-cellulose	1461:1474	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	6	63	theme	phenolic	1156:1163	arg1	groups					1165:1170	various phenolic groups	1148:1170	various phenolic groups	1148:1170	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	4	64	theme	cross-linking	648:660	arg1	process					662:668	the cross-linking process	644:668	the cross-linking process more productive	644:684	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	3	65	from	presence	495:502	arg1	APTES					523:527	APTES	523:527	APTES	523:527	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	1	66	theme	SPI	308:310	arg1	biofilm					313:319	soy protein isolate (SPI) biofilm	287:319	soy protein isolate (SPI) biofilm	287:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	5	67	theme	resistance	850:859	arg1	study					793:797	the study	789:797	the study of the mechanical and thermal properties and water resistance of the film	789:871	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	8	68	theme	soy	1488:1490	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	1	69	theme	biofilm	313:319	arg1	properties					273:282	the mechanical and water-resistance properties	237:282	the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm	237:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	7	70	theme	APTES-modified	1355:1368	arg1	nanocellulose					1370:1382	1 % APTES-modified nanocellulose	1351:1382	1 % APTES-modified nanocellulose	1351:1382	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	8	71	theme	isolate	1500:1506	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	7	72	theme	~119 	1298:1302	arg1	%					1315:1315	~119 % and ~ 112 %	1298:1315	~119 % and ~ 112 %	1298:1315	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	2	73	theme	acid	472:475	arg1	cross-linker					477:488	citric acid cross-linker	465:488	citric acid cross-linker	465:488	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	8	74	theme	SPI	1509:1511	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	8	75	theme	based	1514:1518	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	0	76	theme	nano	23:26	arg1	reinforcement					38:50	silylated nano cellulose reinforcement	13:50	silylated nano cellulose reinforcement	13:50	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	8	77	theme	nanocomposite	1524:1536	arg1	films					1538:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films	1451:1542	silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications	1451:1569	Consequently, this work is expected to offer an effective way for silylated nano-cellulose reinforcing soy protein isolate (SPI) based bio nanocomposite films for packaging applications.					
37192712	2	78	theme	agent	382:386	arg1	nanocellulose					397:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose	336:409	In this work, 3-aminopropyltriethoxysilane (APTES) coupling agent modified nanocellulose was introduced into the SPI matrix in the presence of citric acid cross-linker.					
37192712	0	79	theme	reinforcement	38:50	arg1	Influence					0:8	Influence	0:8	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.	0:191	Influence of silylated nano cellulose reinforcement on the mechanical, water resistance, thermal, morphological and antibacterial properties of soy protein isolate (SPI)-based composite films.					
37192712	3	80	attach	presence	495:502	arg1	APTES					523:527	APTES	523:527	APTES	523:527	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	3	80	attach	presence	495:502	arg2	groups					513:518	amino groups	507:518	amino groups	507:518	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	7	81	theme	nanocellulose	1251:1263	arg1	Modulus					1224:1230	Young's Modulus	1216:1230	Young's Modulus	1216:1230	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	7	81	theme	nanocellulose	1251:1263	arg1	Strength					1203:1210	Tensile Strength	1195:1210	Tensile Strength	1195:1210	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	3	82	link	cross-linked	549:560	arg1	structures					562:571	cross-linked structures	549:571	cross-linked structures	549:571	The presence of amino groups in APTES facilitated to form cross-linked structures with soy protein.					
37192712	5	83	dep	properties	829:838	arg1	the					802:804	the	802:804	the	802:804	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	1	84	theme	soy	287:289	arg1	biofilm					313:319	soy protein isolate (SPI) biofilm	287:319	soy protein isolate (SPI) biofilm	287:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	1	85	theme	isolate	299:305	arg1	biofilm					313:319	soy protein isolate (SPI) biofilm	287:319	soy protein isolate (SPI) biofilm	287:319	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
37192712	6	86	theme	nanocomposite	1071:1083	arg1	film					1085:1088	SPI nanocomposite film	1067:1088	SPI nanocomposite film	1067:1088	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	4	87	theme	Scanning	745:752	arg1	Microscope					763:772	a Scanning Electron Microscope	743:772	a Scanning Electron Microscope (FE-SEM)	743:781	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	4	87	theme	Scanning	745:752	arg1	FE-SEM					775:780	FE-SEM	775:780	FE-SEM	775:780	The incorporation of a citric acid cross-linker made the cross-linking process more productive, and the surface smoothness of the film was confirmed by a Scanning Electron Microscope (FE-SEM).					
37192712	6	88	theme	oil	1058:1060	arg1	coating					1030:1036	coating	1030:1036	coating of citral essential oil onto SPI nanocomposite film	1030:1088	Additionally, coating of citral essential oil onto SPI nanocomposite film displayed antimicrobial properties due to the presence of various phenolic groups in the citral oil.					
37192712	5	89	theme	modified	941:948	arg1	nanocellulose					950:962	the modified nanocellulose	937:962	the modified nanocellulose incorporated film compared to the non-modified one	937:1013	From the study of the mechanical and thermal properties and water resistance of the film, it was confirmed that the results were highly satisfactory for the modified nanocellulose incorporated film compared to the non-modified one.					
37192712	7	90	theme	Tensile	1195:1201	arg1	Strength					1203:1210	Tensile Strength	1195:1210	Tensile Strength	1195:1210	The Tensile Strength and Young's Modulus of silane-modified nanocellulose containing film were enhanced by ~119 % and ~ 112 %, respectively on incorporation of 1 % APTES-modified nanocellulose.					
37192712	1	91	theme	work	218:221	arg1	aim					197:199	The aim	193:199	The aim of this research work	193:221	The aim of this research work is to improve the mechanical and water-resistance properties of soy protein isolate (SPI) biofilm.					
35843005	0	0	theme	model	86:90	arg1	systems					98:104	potato starch-gluten model dough systems	65:104	potato starch-gluten model dough systems	65:104	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	2	1	theme	gelatinization	522:535	arg1	degree					505:510	degree	505:510	degree of starch gelatinization	505:535	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	2	theme	maximum	368:374	arg1	compliance					382:391	maximum creep compliance	368:391	maximum creep compliance of potato starch-gluten composites	368:426	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	1	3	theme	model	256:260	arg1	dough					262:266	starch-gluten model dough	242:266	starch-gluten model dough	242:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	0	4	theme	starch-gluten	72:84	arg1	systems					98:104	potato starch-gluten model dough systems	65:104	potato starch-gluten model dough systems	65:104	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	5	theme	model	1168:1172	arg1	dough					1174:1178	model dough	1168:1178	model dough than native and highly gelatinized starch	1168:1220	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	1	6	theme	dough	262:266	arg1	properties					228:237	the rheological properties	212:237	the rheological properties of starch-gluten model dough	212:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	0	7	theme	systems	98:104	arg1	properties					51:60	Thermal, structural, rheological and morphological properties	0:60	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	8	theme	application	1242:1252	arg1	potential					1254:1262	promising application potential	1232:1262	promising application potential	1232:1262	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	5	9	theme	potato	955:960	arg1	starch					962:967	partially gelatinized potato starch	933:967	partially gelatinized potato starch	933:967	A possible interaction model between partially gelatinized potato starch and gluten was proposed.					
35843005	3	10	theme	starch-gluten	609:621	arg1	dough					629:633	potato starch-gluten model dough	602:633	potato starch-gluten model dough	602:633	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	6	11	dep	texture	1129:1135	arg1	the					1125:1127	the	1125:1127	the	1125:1127	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	6	11	dep	texture	1129:1135	arg1	adaptability					1152:1163	adaptability	1152:1163	adaptability	1152:1163	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	0	12	theme	dough	92:96	arg1	systems					98:104	potato starch-gluten model dough systems	65:104	potato starch-gluten model dough systems	65:104	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	3	13	theme	membrane-like	543:555	arg1	structures					557:566	More membrane-like structures	538:566	More membrane-like structures	538:566	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	5	14	theme	interaction	907:917	arg1	model					919:923	A possible interaction model	896:923	A possible interaction model between partially gelatinized potato starch and gluten	896:978	A possible interaction model between partially gelatinized potato starch and gluten was proposed.					
35843005	6	15	theme	dough	1174:1178	arg1	processing					1141:1150	processing	1141:1150	processing	1141:1150	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	6	15	theme	dough	1174:1178	arg1	texture					1129:1135	texture	1129:1135	texture	1129:1135	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	4	16	theme	gelling	779:785	arg1	interactions					805:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	2	17	theme	Gelatinization	282:295	arg1	temperature					297:307	Gelatinization temperature	282:307	Gelatinization temperature	282:307	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	18	theme	composites	417:426	arg1	temperature					297:307	Gelatinization temperature	282:307	Gelatinization temperature	282:307	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	18	theme	composites	417:426	arg1	region					356:361	linear viscoelastic region	336:361	linear viscoelastic region	336:361	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	18	theme	composites	417:426	arg1	capacity					326:333	water retention capacity	310:333	water retention capacity	310:333	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	18	theme	composites	417:426	arg1	compliance					382:391	maximum creep compliance	368:391	maximum creep compliance of potato starch-gluten composites	368:426	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	6	19	theme	gelatinization	1054:1067	arg1	degree					1044:1049	moderate degree	1035:1049	moderate degree of gelatinization	1035:1067	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	3	20	theme	gelatinization	742:755	arg1	degree					732:737	degree	732:737	degree of gelatinization	732:755	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	4	21	theme	dough	889:893	arg1	functionality					862:874	the desired functionality	850:874	the desired functionality of the model dough	850:893	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	6	22	dep	improve	1117:1123	arg1	has					1228:1230	has	1228:1230	has promising application potential in food industry	1228:1279	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	4	23	theme	major	825:829	arg1	roles					831:835	major roles	825:835	major roles	825:835	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	2	24	theme	starch-gluten	403:415	arg1	composites					417:426	potato starch-gluten composites	396:426	potato starch-gluten composites	396:426	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	2	25	theme	starch	515:520	arg1	gelatinization					522:535	starch gelatinization	515:535	starch gelatinization	515:535	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	3	26	theme	model	623:627	arg1	dough					629:633	potato starch-gluten model dough	602:633	potato starch-gluten model dough	602:633	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	2	27	theme	potato	396:401	arg1	composites					417:426	potato starch-gluten composites	396:426	potato starch-gluten composites	396:426	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	0	28	theme	Thermal	0:6	arg1	properties					51:60	Thermal, structural, rheological and morphological properties	0:60	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	4	29	theme	starch	772:777	arg1	interactions					805:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	2	30	theme	frequency	458:466	arg1	dependence					468:477	frequency dependence	458:477	frequency dependence	458:477	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	4	31	theme	desired	854:860	arg1	functionality					862:874	the desired functionality	850:874	the desired functionality of the model dough	850:893	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	0	32	theme	degree	117:122	arg1	Effect					107:112	Effect	107:112	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	2	33	theme	retention	316:324	arg1	capacity					326:333	water retention capacity	310:333	water retention capacity	310:333	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	3	34	located	observed	590:597	arg2	holes					579:583	larger holes	572:583	larger holes	572:583	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	34	located	observed	590:597	arg2	structures					557:566	More membrane-like structures	538:566	More membrane-like structures	538:566	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	34	located	observed	590:597	arg1	dough					629:633	potato starch-gluten model dough	602:633	potato starch-gluten model dough	602:633	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	1	35	theme	starch	187:192	arg1	gelatinization					194:207	starch gelatinization	187:207	starch gelatinization on the rheological properties of starch-gluten model dough	187:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	0	36	theme	structural	9:18	arg1	properties					51:60	Thermal, structural, rheological and morphological properties	0:60	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	37	theme	moderate	1035:1042	arg1	degree					1044:1049	moderate degree	1035:1049	moderate degree of gelatinization	1035:1067	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	6	38	with	starch	1023:1028	arg1	degree					1044:1049	moderate degree	1035:1049	moderate degree of gelatinization	1035:1067	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	2	39	theme	water	310:314	arg1	capacity					326:333	water retention capacity	310:333	water retention capacity	310:333	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	1	40	theme	gelatinization	194:207	arg1	degree					177:182	degree	177:182	degree of starch gelatinization on the rheological properties of starch-gluten model dough	177:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	0	41	theme	starch	127:132	arg1	pre-gelatinization					134:151	starch pre-gelatinization	127:151	starch pre-gelatinization	127:151	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	0	42	dep	properties	51:60	arg1	Effect					107:112	Effect	107:112	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	43	theme	promising	1232:1240	arg1	potential					1254:1262	promising application potential	1232:1262	promising application potential	1232:1262	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	0	44	theme	rheological	21:31	arg1	properties					51:60	Thermal, structural, rheological and morphological properties	0:60	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	5	45	theme	possible	898:905	arg1	model					919:923	A possible interaction model	896:923	A possible interaction model between partially gelatinized potato starch and gluten	896:978	A possible interaction model between partially gelatinized potato starch and gluten was proposed.					
35843005	4	46	theme	starch-gluten	791:803	arg1	interactions					805:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions	768:816	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	6	47	theme	potato	1016:1021	arg1	starch					1023:1028	Partially gelatinized potato starch	994:1028	Partially gelatinized potato starch with moderate degree of gelatinization	994:1067	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	4	48	theme	model	883:887	arg1	dough					889:893	the model dough	879:893	the model dough	879:893	The starch gelling and starch-gluten interactions played major roles in imparting the desired functionality of the model dough.					
35843005	6	49	theme	native	1185:1190	arg1	starch					1215:1220	native and highly gelatinized starch	1185:1220	native and highly gelatinized starch	1185:1220	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	0	50	theme	morphological	37:49	arg1	properties					51:60	Thermal, structural, rheological and morphological properties	0:60	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.	0:152	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	51	theme	gelatinized	1004:1014	arg1	starch					1023:1028	Partially gelatinized potato starch	994:1028	Partially gelatinized potato starch with moderate degree of gelatinization	994:1067	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	0	52	theme	pre-gelatinization	134:151	arg1	degree					117:122	degree	117:122	degree of starch pre-gelatinization	117:151	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	6	53	theme	gelatinized	1203:1213	arg1	starch					1215:1220	native and highly gelatinized starch	1185:1220	native and highly gelatinized starch	1185:1220	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	3	54	theme	β-turn	712:717	arg1	amount					686:691	the amount	682:691	the amount of random coil and β-turn	682:717	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	54	theme	β-turn	712:717	arg1	coil					703:706	random coil	696:706	random coil	696:706	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	54	theme	β-turn	712:717	arg1	β-turn					712:717	β-turn	712:717	β-turn	712:717	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	1	55	from	gelatinization	194:207	arg1	properties					228:237	the rheological properties	212:237	the rheological properties of starch-gluten model dough	212:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	2	56	theme	viscoelastic	343:354	arg1	region					356:361	linear viscoelastic region	336:361	linear viscoelastic region	336:361	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	3	57	theme	potato	602:607	arg1	dough					629:633	potato starch-gluten model dough	602:633	potato starch-gluten model dough	602:633	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	1	58	theme	rheological	216:226	arg1	properties					228:237	the rheological properties	212:237	the rheological properties of starch-gluten model dough	212:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	1	59	from	properties	228:237	arg1	degree					177:182	degree	177:182	degree of starch gelatinization on the rheological properties of starch-gluten model dough	177:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	3	60	theme	random	696:701	arg1	coil					703:706	random coil	696:706	random coil	696:706	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	6	61	theme	food	1267:1270	arg1	industry					1272:1279	food industry	1267:1279	food industry	1267:1279	Partially gelatinized potato starch with moderate degree of gelatinization could more closely interact with gluten, better improve the texture and processing adaptability of model dough than native and highly gelatinized starch, thus has promising application potential in food industry.					
35843005	1	62	from	degree	177:182	arg1	properties					228:237	the rheological properties	212:237	the rheological properties of starch-gluten model dough	212:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35843005	2	63	theme	linear	336:341	arg1	region					356:361	linear viscoelastic region	336:361	linear viscoelastic region	336:361	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	0	64	theme	potato	65:70	arg1	systems					98:104	potato starch-gluten model dough systems	65:104	potato starch-gluten model dough systems	65:104	Thermal, structural, rheological and morphological properties of potato starch-gluten model dough systems: Effect of degree of starch pre-gelatinization.					
35843005	3	65	theme	coil	703:706	arg1	amount					686:691	the amount	682:691	the amount of random coil and β-turn	682:717	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	65	theme	coil	703:706	arg1	coil					703:706	random coil	696:706	random coil	696:706	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	65	theme	coil	703:706	arg1	β-turn					712:717	β-turn	712:717	β-turn	712:717	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	66	theme	gluten	650:655	arg1	β-sheet					657:663	gluten β-sheet	650:663	gluten β-sheet	650:663	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	5	67	theme	gelatinized	943:953	arg1	starch					962:967	partially gelatinized potato starch	933:967	partially gelatinized potato starch	933:967	A possible interaction model between partially gelatinized potato starch and gluten was proposed.					
35843005	3	68	theme	larger	572:577	arg1	holes					579:583	larger holes	572:583	larger holes	572:583	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	69	theme	β-sheet	657:663	arg1	amount					640:645	the amount	636:645	the amount of gluten β-sheet	636:663	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	3	69	theme	β-sheet	657:663	arg1	β-sheet					657:663	gluten β-sheet	650:663	gluten β-sheet	650:663	More membrane-like structures and larger holes were observed in potato starch-gluten model dough; the amount of gluten β-sheet increased, while the amount of random coil and β-turn decreased as degree of gelatinization increased.					
35843005	2	70	theme	creep	376:380	arg1	compliance					382:391	maximum creep compliance	368:391	maximum creep compliance of potato starch-gluten composites	368:426	Gelatinization temperature, water retention capacity, linear viscoelastic region, and maximum creep compliance of potato starch-gluten composites increased, while enthalpy and frequency dependence decreased with increasing degree of starch gelatinization.					
35843005	1	71	theme	starch-gluten	242:254	arg1	dough					262:266	starch-gluten model dough	242:266	starch-gluten model dough	242:266	The effect elicited by degree of starch gelatinization on the rheological properties of starch-gluten model dough was examined.					
35567978	4	0	theme	good	688:691	arg1	biocompatibility					693:708	good biocompatibility	688:708	good biocompatibility	688:708	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	3	1	theme	rhombohedral	497:508	arg1	size					479:482	an average particle size	459:482	an average particle size of 44 nm and rhombohedral morphology	459:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	4	2	theme	cells	593:597	arg1	damage					559:564	no cell damage	551:564	no cell damage of human Caco-2 epithelial cells	551:597	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	5	3	theme	packaging	922:930	arg1	safety					910:915	their safety	904:915	their safety	904:915	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	5	3	theme	packaging	922:930	arg1	material					932:939	a packaging material	920:939	a packaging material	920:939	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	4	4	theme	Fe2TiO5	522:528	arg1	nanoparticles					530:542	Fe2TiO5 nanoparticles	522:542	Fe2TiO5 nanoparticles	522:542	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	1	5	theme	food	256:259	arg1	freshness					261:269	food freshness	256:269	food freshness	256:269	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	6	6	from	test	1082:1085	arg1	fruit					1096:1100	fresh fruit	1090:1100	fresh fruit	1090:1100	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	2	7	theme	Fe2TiO5	286:292	arg1	nanoparticles					294:306	Fe2TiO5 nanoparticles	286:306	Fe2TiO5 nanoparticles	286:306	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	2	7	theme	Fe2TiO5	286:292	arg1	enforcement					377:387	an enforcement	374:387	an enforcement of alginate food packaging film	374:419	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	5	8	theme	Fe2TiO5	746:752	arg1	nanoparticles					754:766	Fe2TiO5 nanoparticles	746:766	Fe2TiO5 nanoparticles	746:766	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	4	9	theme	panel	649:653	arg1	growth					637:642	growth	637:642	growth of a panel of bacterial strains	637:674	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	5	10	theme	nanoparticles	754:766	arg1	incorporation					729:741	incorporation	729:741	incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method	729:813	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	3	11	theme	44 nm	487:491	arg1	size					479:482	an average particle size	459:482	an average particle size of 44 nm and rhombohedral morphology	459:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	5	12	theme	ions	853:856	arg1	migration					823:831	no migration	820:831	no migration of iron or titanium ions from films to food	820:875	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	3	13	theme	particle	470:477	arg1	size					479:482	an average particle size	459:482	an average particle size of 44 nm and rhombohedral morphology	459:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	3	14	dep	44 nm	487:491	arg1	morphology					510:519	morphology	510:519	morphology	510:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	2	15	theme	alginate	392:399	arg1	film					416:419	alginate food packaging film	392:419	alginate food packaging film	392:419	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	5	16	from	migration	823:831	arg1	films					863:867	films	863:867	films	863:867	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	6	17	theme	DPPḢ	1030:1033	arg1	assay					1035:1039	the DPPḢ assay	1026:1039	the DPPḢ assay	1026:1039	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	1	18	theme	emerging	87:94	arg1	technology					96:105	An emerging technology	84:105	An emerging technology of active packaging	84:125	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	1	19	theme	oxygen	183:188	arg1	transfer					190:197	the oxygen transfer	179:197	the oxygen transfer	179:197	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	5	20	theme	solvent	792:798	arg1	method					808:813	the solvent casting method	788:813	the solvent casting method	788:813	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	3	21	theme	Pure	422:425	arg1	nanoparticles					441:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	0	22	theme	Antioxidant	0:10	arg1	Fe2TiO5					30:36	Antioxidant and cell-friendly Fe2TiO5	0:36	Antioxidant and cell-friendly Fe2TiO5	0:36	Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application.					
35567978	4	23	theme	bacterial	658:666	arg1	strains					668:674	bacterial strains	658:674	bacterial strains	658:674	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	5	24	dep	show	815:818	arg1	simulants					877:885	simulants	877:885	show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material	815:939	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	3	25	theme	phase	427:431	arg1	nanoparticles					441:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	5	26	theme	iron	836:839	arg1	ions					853:856	iron or titanium ions	836:856	ions	853:856	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	6	27	theme	antioxidant	983:993	arg1	efficiency					995:1004	strong antioxidant efficiency	976:1004	strong antioxidant efficiency	976:1004	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	1	28	theme	active	110:115	arg1	packaging					117:125	active packaging	110:125	active packaging	110:125	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	3	29	theme	average	462:468	arg1	size					479:482	an average particle size	459:482	an average particle size of 44 nm and rhombohedral morphology	459:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	0	30	theme	cell-friendly	16:28	arg1	Fe2TiO5					30:36	Antioxidant and cell-friendly Fe2TiO5	0:36	Antioxidant and cell-friendly Fe2TiO5	0:36	Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application.					
35567978	4	31	theme	Caco-2	575:580	arg1	cells					593:597	human Caco-2 epithelial cells	569:597	human Caco-2 epithelial cells	569:597	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	4	32	theme	inhibitory	611:620	arg1	effect					622:627	no inhibitory effect	608:627	no inhibitory effect	608:627	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	1	33	theme	packaging	117:125	arg1	technology					96:105	An emerging technology	84:105	An emerging technology of active packaging	84:125	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	2	34	theme	film	416:419	arg1	nanoparticles					294:306	Fe2TiO5 nanoparticles	286:306	Fe2TiO5 nanoparticles	286:306	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	2	34	theme	film	416:419	arg1	enforcement					377:387	an enforcement	374:387	an enforcement of alginate food packaging film	374:419	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	5	35	theme	casting	800:806	arg1	method					808:813	the solvent casting method	788:813	the solvent casting method	788:813	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	4	36	theme	human	569:573	arg1	cells					593:597	human Caco-2 epithelial cells	569:597	human Caco-2 epithelial cells	569:597	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	3	37	contain	had	455:457	arg2	size					479:482	an average particle size	459:482	an average particle size of 44 nm and rhombohedral morphology	459:519	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	3	37	contain	had	455:457	arg1	nanoparticles					441:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	6	38	theme	strong	976:981	arg1	efficiency					995:1004	strong antioxidant efficiency	976:1004	strong antioxidant efficiency	976:1004	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	4	39	theme	strains	668:674	arg1	panel					649:653	a panel	647:653	a panel of bacterial strains	647:674	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	2	40	theme	packaging	406:414	arg1	film					416:419	alginate food packaging film	392:419	alginate food packaging film	392:419	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	3	41	theme	Fe2TiO5	433:439	arg1	nanoparticles					441:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles	422:453	Pure phase Fe2TiO5 nanoparticles had an average particle size of 44 nm and rhombohedral morphology.					
35567978	4	42	theme	epithelial	582:591	arg1	cells					593:597	human Caco-2 epithelial cells	569:597	human Caco-2 epithelial cells	569:597	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	1	43	theme	free	221:224	arg1	radicals					226:233	free radicals	221:233	free radicals	221:233	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	0	44	theme	packaging	61:69	arg1	application					71:81	food packaging application	56:81	food packaging application	56:81	Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application.					
35567978	5	45	from	films	863:867	arg1	ions					853:856	iron or titanium ions	836:856	ions	853:856	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	5	45	from	films	863:867	arg1	migration					823:831	no migration	820:831	no migration of iron or titanium ions from films to food	820:875	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	2	46	theme	sol-gel	342:348	arg1	method					350:355	a modified sol-gel method	331:355	a modified sol-gel method	331:355	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	0	47	theme	food	56:59	arg1	application					71:81	food packaging application	56:81	food packaging application	56:81	Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application.					
35567978	4	48	theme	cell	554:557	arg1	damage					559:564	no cell damage	551:564	no cell damage of human Caco-2 epithelial cells	551:597	Fe2TiO5 nanoparticles induce no cell damage of human Caco-2 epithelial cells and show no inhibitory effect towards growth of a panel of bacterial strains, suggesting good biocompatibility.					
35567978	2	49	theme	modified	333:340	arg1	method					350:355	a modified sol-gel method	331:355	a modified sol-gel method	331:355	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	6	50	theme	Fe2TiO5	942:948	arg1	nanoparticles					950:962	Fe2TiO5 nanoparticles	942:962	Fe2TiO5 nanoparticles	942:962	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	1	51	theme	radicals	226:233	arg1	transfer					190:197	the oxygen transfer	179:197	the oxygen transfer	179:197	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	1	51	theme	radicals	226:233	arg1	reactivity					207:216	the reactivity	203:216	the reactivity of free radicals, which both destruct food freshness	203:269	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	1	52	dep	destruct	247:254	arg1	both					242:245	both	242:245	both	242:245	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	6	53	theme	preservation	1069:1080	arg1	test					1082:1085	a preservation test	1067:1085	a preservation test on fresh fruit	1067:1100	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	1	54	theme	food	151:154	arg1	life					162:165	food shelf life	151:165	food shelf life	151:165	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	2	55	theme	food	401:404	arg1	film					416:419	alginate food packaging film	392:419	alginate food packaging film	392:419	In this work, Fe2TiO5 nanoparticles were synthesized using a modified sol-gel method and evaluated as an enforcement of alginate food packaging film.					
35567978	5	56	theme	titanium	844:851	arg1	ions					853:856	iron or titanium ions	836:856	ions	853:856	Films obtained by incorporation of Fe2TiO5 nanoparticles into alginate using the solvent casting method show no migration of iron or titanium ions from films to food simulants again suggesting their safety as a packaging material.					
35567978	1	57	theme	shelf	156:160	arg1	life					162:165	food shelf life	151:165	food shelf life	151:165	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
35567978	6	58	theme	fresh	1090:1094	arg1	fruit					1096:1100	fresh fruit	1090:1100	fresh fruit	1090:1100	Fe2TiO5 nanoparticles also showed strong antioxidant efficiency as determined using the DPPḢ assay, and confirmed further in a preservation test on fresh fruit.					
35567978	1	59	theme	life	162:165	arg1	prolongation					135:146	prolongation	135:146	prolongation of food shelf life	135:165	An emerging technology of active packaging enables prolongation of food shelf life by limiting the oxygen transfer and the reactivity of free radicals, which both destruct food freshness.					
36152092	0	0	theme	tannery	86:92	arg1	films					130:134	tannery solid waste-based gelatin composite films	86:134	tannery solid waste-based gelatin composite films	86:134	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	2	1	theme	hydrochloric	477:488	arg1	acid					490:493	hydrochloric acid	477:493	hydrochloric acid (HCNC)	477:500	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	2	1	theme	hydrochloric	477:488	arg1	HCNC					496:499	HCNC	496:499	HCNC	496:499	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	8	2	theme	value	1424:1428	arg1	T280					1430:1433	transmittance value T280	1410:1433	transmittance value T280 of 0.19%	1410:1442	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	9	3	theme	initial	1489:1495	arg1	mass					1497:1500	initial mass	1489:1500	initial mass	1489:1500	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	4	4	theme	mechanical	770:779	arg1	stiffness					781:789	mechanical stiffness	770:789	mechanical stiffness of rawhide trimming waste-based gelatin films	770:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	10	5	theme	seeds	1621:1625	arg1	application					1597:1607	single-use packaging application	1576:1607	single-use packaging application of eggplant seeds	1576:1625	Furthermore, based on the optimized system, single-use packaging application of eggplant seeds has been demonstrated.					
36152092	7	6	theme	cellulose	1199:1207	arg1	nanocrystal					1212:1222	cellulose II nanocrystal	1199:1222	cellulose II nanocrystal	1199:1222	Strong interfacial non-covalent and hydrogen bonding interactions between gelatin and cellulose II nanocrystal have likely enhanced the properties of the composite films.					
36152092	0	7	theme	waste-based	100:110	arg1	films					130:134	tannery solid waste-based gelatin composite films	86:134	tannery solid waste-based gelatin composite films	86:134	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	3	8	theme	HCNC	650:653	arg1	crystallinity					617:629	The crystallinity	613:629	The crystallinity of PCNC, CCNC, and HCNC	613:653	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	3	8	theme	HCNC	650:653	arg1	%					675:675	81.1%	671:675	81.1%	671:675	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	4	9	theme	rawhide	794:800	arg1	films					831:835	rawhide trimming waste-based gelatin films	794:835	rawhide trimming waste-based gelatin films	794:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	7	10	theme	bonding	1158:1164	arg1	interactions					1166:1177	Strong interfacial non-covalent and hydrogen bonding interactions	1113:1177	interactions	1166:1177	Strong interfacial non-covalent and hydrogen bonding interactions between gelatin and cellulose II nanocrystal have likely enhanced the properties of the composite films.					
36152092	9	11	dep	79.9	1480:1483	arg1	to					1477:1478	to	1477:1478	to	1477:1478	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	1	12	theme	different	267:275	arg1	techniques					288:297	three different hydrolysis techniques	261:297	three different hydrolysis techniques	261:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	0	13	theme	solid	94:98	arg1	films					130:134	tannery solid waste-based gelatin composite films	86:134	tannery solid waste-based gelatin composite films	86:134	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	1	14	theme	biodegradable	371:383	arg1	material					395:402	a biodegradable packaging material	369:402	a biodegradable packaging material	369:402	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	8	15	theme	CNC	1301:1303	arg1	Incorporation					1284:1296	Incorporation	1284:1296	Incorporation of CNC II	1284:1306	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	5	16	theme	Maximum	878:884	arg1	decomposition					894:906	Maximum thermal decomposition	878:906	Maximum thermal decomposition with Tmax of 329 °C	878:926	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	1	17	theme	hydrolysis	277:286	arg1	techniques					288:297	three different hydrolysis techniques	261:297	three different hydrolysis techniques	261:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	0	18	theme	composite	120:128	arg1	films					130:134	tannery solid waste-based gelatin composite films	86:134	tannery solid waste-based gelatin composite films	86:134	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	1	19	theme	packaging	385:393	arg1	material					395:402	a biodegradable packaging material	369:402	a biodegradable packaging material	369:402	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	7	20	theme	composite	1267:1275	arg1	films					1277:1281	the composite films	1263:1281	the composite films	1263:1281	Strong interfacial non-covalent and hydrogen bonding interactions between gelatin and cellulose II nanocrystal have likely enhanced the properties of the composite films.					
36152092	5	21	theme	thermal	886:892	arg1	decomposition					894:906	Maximum thermal decomposition	878:906	Maximum thermal decomposition with Tmax of 329 °C	878:926	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	10	22	theme	single-use	1576:1585	arg1	application					1597:1607	single-use packaging application	1576:1607	single-use packaging application of eggplant seeds	1576:1625	Furthermore, based on the optimized system, single-use packaging application of eggplant seeds has been demonstrated.					
36152092	0	23	theme	gelatin	112:118	arg1	films					130:134	tannery solid waste-based gelatin composite films	86:134	tannery solid waste-based gelatin composite films	86:134	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	2	24	theme	XRD	599:601	arg1	DLS					576:578	DLS	576:578	DLS	576:578	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	2	24	theme	XRD	599:601	arg1	analysis					603:610	XRD analysis	599:610	XRD analysis	599:610	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	6	25	theme	microbial	1095:1103	arg1	strain					1105:1110	Gram-positive S. aureus microbial strain	1071:1110	Gram-positive S. aureus microbial strain	1071:1110	Films with CNC II were structurally stable and sufficiently antibacterial against Gram-positive S. aureus microbial strain.					
36152092	1	26	theme	cellulose	196:204	arg1	CNC					222:224	CNC II	222:227	CNC II	222:227	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	1	26	theme	cellulose	196:204	arg1	nanocrystal					209:219	cellulose II nanocrystal	196:219	cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques	196:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	5	27	with	films	953:957	arg1	nano-reinforcement					969:986	PCNC nano-reinforcement	964:986	PCNC nano-reinforcement	964:986	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	7	28	theme	films	1277:1281	arg1	properties					1249:1258	the properties	1245:1258	the properties of the composite films	1245:1281	Strong interfacial non-covalent and hydrogen bonding interactions between gelatin and cellulose II nanocrystal have likely enhanced the properties of the composite films.					
36152092	2	29	theme	citric	453:458	arg1	CCNC					466:469	CCNC	466:469	CCNC	466:469	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	2	29	theme	citric	453:458	arg1	acid					460:463	citric acid	453:463	citric acid (CCNC)	453:470	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	8	30	theme	%	1442:1442	arg1	T280					1430:1433	transmittance value T280	1410:1433	transmittance value T280 of 0.19%	1410:1442	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	5	31	theme	gelatin	945:951	arg1	films					953:957	gelatin films	945:957	gelatin films with PCNC nano-reinforcement	945:986	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	6	32	dep	S.	1085:1086	arg1	aureus					1088:1093	aureus	1088:1093	aureus	1088:1093	Films with CNC II were structurally stable and sufficiently antibacterial against Gram-positive S. aureus microbial strain.					
36152092	0	33	theme	techniques	25:34	arg1	Influence					0:8	Influence	0:8	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.	0:135	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	4	34	theme	gelatin	864:870	arg1	film					872:875	gelatin film	864:875	gelatin film	864:875	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	6	35	theme	Gram-positive	1071:1083	arg1	strain					1105:1110	Gram-positive S. aureus microbial strain	1071:1110	Gram-positive S. aureus microbial strain	1071:1110	Films with CNC II were structurally stable and sufficiently antibacterial against Gram-positive S. aureus microbial strain.					
36152092	5	36	theme	°C	925:926	arg1	decomposition					894:906	Maximum thermal decomposition	878:906	Maximum thermal decomposition with Tmax of 329 °C	878:926	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	0	37	theme	preparation	13:23	arg1	techniques					25:34	preparation techniques	13:34	preparation techniques of cellulose II nanocrystals as reinforcement	13:80	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	2	38	theme	crystalline	532:542	arg1	character					544:552	morphological and crystalline character	514:552	morphological and crystalline character	514:552	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	8	39	theme	transmittance	1410:1422	arg1	T280					1430:1433	transmittance value T280	1410:1433	transmittance value T280 of 0.19%	1410:1442	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	9	40	theme	burial	1524:1529	arg1	days					1511:1514	7 days	1509:1514	7 days of soil burial	1509:1529	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	6	41	theme	S.	1085:1086	arg1	strain					1105:1110	Gram-positive S. aureus microbial strain	1071:1110	Gram-positive S. aureus microbial strain	1071:1110	Films with CNC II were structurally stable and sufficiently antibacterial against Gram-positive S. aureus microbial strain.					
36152092	0	42	theme	cellulose	39:47	arg1	nanocrystals					52:63	cellulose II nanocrystals	39:63	cellulose II nanocrystals	39:63	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	4	43	theme	CNC	733:735	arg1	incorporation					747:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	10	44	theme	eggplant	1612:1619	arg1	seeds					1621:1625	eggplant seeds	1612:1625	eggplant seeds	1612:1625	Furthermore, based on the optimized system, single-use packaging application of eggplant seeds has been demonstrated.					
36152092	5	45	with	decomposition	894:906	arg1	Tmax					913:916	Tmax	913:916	Tmax	913:916	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	2	46	theme	morphological	514:526	arg1	character					544:552	morphological and crystalline character	514:552	morphological and crystalline character	514:552	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	4	47	theme	crystalline	721:731	arg1	incorporation					747:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	2	48	theme	hydrogen	427:434	arg1	peroxide					436:443	hydrogen peroxide	427:443	hydrogen peroxide (PCNC)	427:450	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	2	48	theme	hydrogen	427:434	arg1	PCNC					446:449	PCNC	446:449	PCNC	446:449	CNC II isolated using hydrogen peroxide (PCNC), citric acid (CCNC), and hydrochloric acid (HCNC) differed in morphological and crystalline character as investigated using DLS, FE-SEM, FTIR, and XRD analysis.					
36152092	0	49	theme	nanocrystals	52:63	arg1	techniques					25:34	preparation techniques	13:34	preparation techniques of cellulose II nanocrystals as reinforcement	13:80	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	1	50	theme	functional	319:328	arg1	properties					330:339	its functional properties	315:339	its functional properties	315:339	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	4	51	theme	waste-based	811:821	arg1	films					831:835	rawhide trimming waste-based gelatin films	794:835	rawhide trimming waste-based gelatin films	794:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	6	52	with	Films	989:993	arg1	CNC					1000:1002	CNC II	1000:1005	CNC II	1000:1005	Films with CNC II were structurally stable and sufficiently antibacterial against Gram-positive S. aureus microbial strain.					
36152092	8	53	theme	absorbed	1372:1379	arg1	radiation					1384:1392	absorbed UV radiation	1372:1392	absorbed UV radiation	1372:1392	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	8	54	theme	surface	1320:1326	arg1	wettability					1328:1338	the surface wettability	1316:1338	the surface wettability of the films	1316:1351	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	9	55	theme	Nanocomposite	1445:1457	arg1	films					1459:1463	Nanocomposite films	1445:1463	Nanocomposite films	1445:1463	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	0	56	theme	II	49:50	arg1	nanocrystals					52:63	cellulose II nanocrystals	39:63	cellulose II nanocrystals	39:63	Influence of preparation techniques of cellulose II nanocrystals as reinforcement for tannery solid waste-based gelatin composite films.					
36152092	4	57	theme	trimming	802:809	arg1	films					831:835	rawhide trimming waste-based gelatin films	794:835	rawhide trimming waste-based gelatin films	794:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	3	58	theme	CCNC	640:643	arg1	crystallinity					617:629	The crystallinity	613:629	The crystallinity of PCNC, CCNC, and HCNC	613:653	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	3	58	theme	CCNC	640:643	arg1	%					675:675	81.1%	671:675	81.1%	671:675	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	4	59	theme	PCNC	741:744	arg1	incorporation					747:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation	710:759	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	9	60	theme	mass	1497:1500	arg1	%					1484:1484	up to 79.9%	1474:1484	up to 79.9% of initial mass	1474:1500	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	9	60	theme	mass	1497:1500	arg1	mass					1497:1500	initial mass	1489:1500	initial mass	1489:1500	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	3	61	theme	86.1	689:692	arg1	%					693:693	86.1%	689:693	86.1%	689:693	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	4	62	theme	films	831:835	arg1	stiffness					781:789	mechanical stiffness	770:789	mechanical stiffness of rawhide trimming waste-based gelatin films	770:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	8	63	theme	films	1347:1351	arg1	wettability					1328:1338	the surface wettability	1316:1338	the surface wettability of the films	1316:1351	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	1	64	theme	Tannery	137:143	arg1	film					175:178	Tannery waste-based gelatin composite film	137:178	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques	137:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	9	65	theme	soil	1519:1522	arg1	burial					1524:1529	soil burial	1519:1529	soil burial	1519:1529	Nanocomposite films degraded up to 79.9% of initial mass within 7 days of soil burial.					
36152092	4	66	theme	gelatin	823:829	arg1	films					831:835	rawhide trimming waste-based gelatin films	794:835	rawhide trimming waste-based gelatin films	794:835	The highly crystalline CNC II (PCNC) incorporation improved mechanical stiffness of rawhide trimming waste-based gelatin films by 50% compared to control gelatin film.					
36152092	3	67	theme	PCNC	634:637	arg1	crystallinity					617:629	The crystallinity	613:629	The crystallinity of PCNC, CCNC, and HCNC	613:653	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	3	67	theme	PCNC	634:637	arg1	%					675:675	81.1%	671:675	81.1%	671:675	The crystallinity of PCNC, CCNC, and HCNC was found to be 81.1%, 75.4%, and 86.1%, respectively.					
36152092	8	68	theme	UV	1381:1382	arg1	radiation					1384:1392	absorbed UV radiation	1372:1392	absorbed UV radiation	1372:1392	Incorporation of CNC II reduced the surface wettability of the films and nanocomposites absorbed UV radiation as evidenced by transmittance value T280 of 0.19%.					
36152092	1	69	theme	waste-based	145:155	arg1	film					175:178	Tannery waste-based gelatin composite film	137:178	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques	137:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	5	70	theme	PCNC	964:967	arg1	nano-reinforcement					969:986	PCNC nano-reinforcement	964:986	PCNC nano-reinforcement	964:986	Maximum thermal decomposition with Tmax of 329 °C was obtained for gelatin films with PCNC nano-reinforcement.					
36152092	1	71	theme	gelatin	157:163	arg1	film					175:178	Tannery waste-based gelatin composite film	137:178	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques	137:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	10	72	theme	packaging	1587:1595	arg1	application					1597:1607	single-use packaging application	1576:1607	single-use packaging application of eggplant seeds	1576:1625	Furthermore, based on the optimized system, single-use packaging application of eggplant seeds has been demonstrated.					
36152092	1	73	theme	wet	245:247	arg1	wipes					249:253	wet wipes	245:253	wet wipes using three different hydrolysis techniques	245:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	1	74	theme	possible	345:352	arg1	utilization					354:364	possible utilization	345:364	possible utilization as a biodegradable packaging material	345:402	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	1	75	theme	composite	165:173	arg1	film					175:178	Tannery waste-based gelatin composite film	137:178	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques	137:297	Tannery waste-based gelatin composite film reinforced with cellulose II nanocrystal (CNC II) extracted from wet wipes using three different hydrolysis techniques is explored for its functional properties and possible utilization as a biodegradable packaging material.					
36152092	10	76	theme	optimized	1558:1566	arg1	system					1568:1573	the optimized system	1554:1573	the optimized system	1554:1573	Furthermore, based on the optimized system, single-use packaging application of eggplant seeds has been demonstrated.					
36152092	7	77	theme	hydrogen	1149:1156	arg1	interactions					1166:1177	Strong interfacial non-covalent and hydrogen bonding interactions	1113:1177	interactions	1166:1177	Strong interfacial non-covalent and hydrogen bonding interactions between gelatin and cellulose II nanocrystal have likely enhanced the properties of the composite films.					
35358565	7	0	theme	0.5 wt	1185:1190	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	1	dep	cytotoxicity	1052:1063	arg1	The					1048:1050	The	1048:1050	The	1048:1050	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	2	from	%	1191:1191	arg1	conditions					1201:1210	both conditions	1196:1210	both conditions	1196:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	3	theme	composite	1099:1107	arg1	NFs					1109:1111	the composite NFs	1095:1111	the composite NFs	1095:1111	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	4	4	theme	reduced	716:722	arg1	AGC					743:745	AGC	743:745	AGC	743:745	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	4	4	theme	reduced	716:722	arg1	GO-graft-Chitosan					724:740	reduced GO-graft-Chitosan	716:740	Ag-decorated reduced GO-graft-Chitosan (AGC) NPs	703:750	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	0	5	theme	Electrospun	0:10	arg1	Ag-decorated					12:23	Electrospun Ag-decorated	0:23	Electrospun Ag-decorated	0:23	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	0	6	theme	photocatalytic	91:104	arg1	activity					106:113	visible light photocatalytic activity	77:113	visible light photocatalytic activity	77:113	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	7	7	theme	NFs	1153:1155	arg1	order					1134:1138	the order	1130:1138	the order of composite NFs	1130:1155	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	8	theme	antibacterial	1069:1081	arg1	activity					1083:1090	antibacterial activity	1069:1090	antibacterial activity	1069:1090	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	9	9	theme	optimum	1400:1406	arg1	NFs					1360:1362	The composite NFs	1346:1362	The composite NFs (5.0 wt%)	1346:1372	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	9	theme	optimum	1400:1406	arg1	NFs					1408:1410	the optimum NFs	1396:1410	the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1396:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	2	10	contain	possessing	237:246	arg1	candidates					330:339	excellent candidates	320:339	excellent candidates for water disinfection	320:362	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	2	10	contain	possessing	237:246	arg2	properties					277:286	intrinsic antibacterial properties	253:286	intrinsic antibacterial properties	253:286	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	2	10	contain	possessing	237:246	arg1	nanomaterials					223:235	The nanomaterials	219:235	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity	219:314	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	2	10	contain	possessing	237:246	arg2	activity					307:314	photocatalytic activity	292:314	photocatalytic activity	292:314	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	5	11	theme	polyacrylonitrile	767:783	arg1	NPs					799:801	polyacrylonitrile (PAN) and AGC NPs	767:801	polyacrylonitrile (PAN) and AGC NPs	767:801	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	10	12	theme	1.11 MPa	1693:1700	arg1	180 °C					1662:1667	180 °C	1662:1667	180 °C	1662:1667	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	10	12	theme	1.11 MPa	1693:1700	arg1	strength					1681:1688	tensile strength	1673:1688	tensile strength	1673:1688	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	5	13	theme	%	870:870	arg1	concentrations					828:841	various concentrations	820:841	various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt%	820:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	10	14	dep	180 °C	1662:1667	arg1	up					1656:1657	up	1656:1657	up	1656:1657	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	2	15	theme	antibacterial	263:275	arg1	properties					277:286	intrinsic antibacterial properties	253:286	intrinsic antibacterial properties	253:286	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	5	16	theme	electrospun	912:922	arg1	NFs					934:936	the electrospun composite NFs	908:936	the electrospun composite NFs	908:936	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	2	17	theme	excellent	320:328	arg1	nanomaterials					223:235	The nanomaterials	219:235	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity	219:314	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	2	17	theme	excellent	320:328	arg1	candidates					330:339	excellent candidates	320:339	excellent candidates for water disinfection	320:362	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	9	18	theme	%	1437:1437	arg1	viability					1422:1430	cell viability	1417:1430	cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1417:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	5	19	theme	NPs	799:801	arg1	blends					757:762	The blends	753:762	The blends of polyacrylonitrile (PAN) and AGC NPs	753:801	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	10	20	theme	21.71	1707:1711	arg1	%					1712:1712	%	1712:1712	%	1712:1712	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	3	21	theme	nanomaterials	386:398	arg1	form					378:381	The powdered form	365:381	The powdered form of nanomaterials	365:398	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	7	22	theme	1.0 wt	1176:1181	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	9	23	theme	%	1457:1457	arg1	viability					1422:1430	cell viability	1417:1430	cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1417:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	6	24	theme	SEM/EDAX	973:980	arg1	analyses					982:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	8	25	theme	light	1306:1310	arg1	irradiation					1312:1322	light irradiation	1306:1322	light irradiation	1306:1322	Their cytotoxicity and antibacterial activity were more under light irradiation compared to the dark.					
35358565	0	26	theme	antibacterial	119:131	arg1	performance					133:143	antibacterial performance	119:143	antibacterial performance	119:143	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	3	27	theme	photocatalytic	509:522	arg1	activity					524:531	the photocatalytic activity	505:531	the photocatalytic activity	505:531	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	6	28	theme	successful	1005:1014	arg1	preparation					1016:1026	the successful preparation	1001:1026	the successful preparation of the NPs and NFs	1001:1045	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	7	29	theme	%	1182:1182	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	5	30	theme	%	852:852	arg1	concentrations					828:841	various concentrations	820:841	various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt%	820:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	9	31	theme	inhibition	1489:1498	arg1	IZD					1515:1517	IZD	1515:1517	IZD	1515:1517	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	31	theme	inhibition	1489:1498	arg1	diameter					1505:1512	inhibition zone diameter	1489:1512	inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1489:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	6	32	theme	NFs	1043:1045	arg1	preparation					1016:1026	the successful preparation	1001:1026	the successful preparation of the NPs and NFs	1001:1045	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	5	33	theme	1.0 wt	855:860	arg1	%					861:861	1.0 wt%	855:861	1.0 wt%	855:861	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	2	34	theme	water	345:349	arg1	disinfection					351:362	water disinfection	345:362	water disinfection	345:362	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	1	35	theme	water	163:167	arg1	treatment					150:158	The treatment	146:158	The treatment of water contaminated by bacteria	146:192	The treatment of water contaminated by bacteria is becoming a necessity.					
35358565	6	36	theme	NPs	1035:1037	arg1	preparation					1016:1026	the successful preparation	1001:1026	the successful preparation of the NPs and NFs	1001:1045	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	0	37	theme	light	85:89	arg1	activity					106:113	visible light photocatalytic activity	77:113	visible light photocatalytic activity	77:113	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	9	38	with	NFs	1408:1410	arg1	viability					1422:1430	cell viability	1417:1430	cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1417:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	0	39	theme	composite	51:59	arg1	nanofibers					61:70	GO-graft-chitosan composite nanofibers	33:70	GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance	33:143	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	5	40	theme	various	820:826	arg1	concentrations					828:841	various concentrations	820:841	various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt%	820:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	7	41	theme	˃	1183:1183	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	3	42	from	UV-light	553:560	arg1	transition					537:546	transition	537:546	transition from UV-light to visiblelight	537:576	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	3	42	from	UV-light	553:560	arg1	activity					524:531	the photocatalytic activity	505:531	the photocatalytic activity	505:531	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	4	43	theme	silver	662:667	arg1	nanoparticles					669:681	silver nanoparticles	662:681	silver nanoparticles (Ag NPs)	662:690	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	4	43	theme	silver	662:667	arg1	NPs					687:689	Ag NPs	684:689	Ag NPs	684:689	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	7	44	theme	NFs	1109:1111	arg1	activity					1083:1090	antibacterial activity	1069:1090	antibacterial activity	1069:1090	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	44	theme	NFs	1109:1111	arg1	cytotoxicity					1052:1063	cytotoxicity	1052:1063	cytotoxicity	1052:1063	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	10	45	theme	optimum	1609:1615	arg1	NFs					1627:1629	The optimum composite NFs	1605:1629	The optimum composite NFs	1605:1629	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	9	46	theme	13 mm	1545:1549	arg1	L929 cells					1474:1483	L929 cells	1474:1483	L929 cells	1474:1483	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	46	theme	13 mm	1545:1549	arg1	IZD					1515:1517	IZD	1515:1517	IZD	1515:1517	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	46	theme	13 mm	1545:1549	arg1	diameter					1505:1512	inhibition zone diameter	1489:1512	inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1489:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	7	47	theme	composite	1143:1151	arg1	NFs					1153:1155	composite NFs	1143:1155	composite NFs	1143:1155	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	10	48	theme	thermal	1638:1644	arg1	stability					1646:1654	thermal stability	1638:1654	thermal stability up to 180 °C and tensile strength of 1.11 MPa	1638:1700	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	4	49	theme	Ag-decorated	703:714	arg1	NPs					748:750	Ag-decorated reduced GO-graft-Chitosan (AGC) NPs	703:750	Ag-decorated reduced GO-graft-Chitosan (AGC) NPs	703:750	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	10	50	theme	tensile	1673:1679	arg1	strength					1681:1688	tensile strength	1673:1688	tensile strength	1673:1688	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	5	51	theme	10.0 wt	877:883	arg1	%					884:884	10.0 wt%	877:884	10.0 wt%	877:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	6	52	theme	XRD	964:966	arg1	analyses					982:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	4	53	theme	GO-graft-Chitosan	724:740	arg1	NPs					748:750	Ag-decorated reduced GO-graft-Chitosan (AGC) NPs	703:750	Ag-decorated reduced GO-graft-Chitosan (AGC) NPs	703:750	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	5	54	theme	%	861:861	arg1	concentrations					828:841	various concentrations	820:841	various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt%	820:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	6	55	theme	Raman	957:961	arg1	analyses					982:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	9	56	theme	light	1586:1590	arg1	irradiation					1592:1602	the light irradiation	1582:1602	the light irradiation	1582:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	2	57	theme	photocatalytic	292:305	arg1	activity					307:314	photocatalytic activity	292:314	photocatalytic activity	292:314	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	5	58	theme	%	884:884	arg1	concentrations					828:841	various concentrations	820:841	various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt%	820:884	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	9	59	theme	cell	1417:1420	arg1	viability					1422:1430	cell viability	1417:1430	cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1417:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	6	60	theme	UV-Vis	949:954	arg1	analyses					982:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	5	61	used	used	890:893	arg2	blends					757:762	The blends	753:762	The blends of polyacrylonitrile (PAN) and AGC NPs	753:801	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	6	62	theme	FTIR/ATR	939:946	arg1	analyses					982:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses	939:989	FTIR/ATR, UV-Vis, Raman, XRD, and SEM/EDAX analyses confirmed the successful preparation of the NPs and NFs.					
35358565	5	63	theme	composite	924:932	arg1	NFs					934:936	the electrospun composite NFs	908:936	the electrospun composite NFs	908:936	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	3	64	theme	powdered	369:376	arg1	form					378:381	The powdered form	365:381	The powdered form of nanomaterials	365:398	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	5	65	theme	AGC	795:797	arg1	NPs					799:801	polyacrylonitrile (PAN) and AGC NPs	767:801	polyacrylonitrile (PAN) and AGC NPs	767:801	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	10	66	theme	%	1712:1712	arg1	elongation					1714:1723	21.71% elongation	1707:1723	21.71% elongation	1707:1723	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35358565	5	67	dep	polyacrylonitrile	767:783	arg1	PAN					786:788	PAN	786:788	PAN	786:788	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	4	68	theme	graphene	585:592	arg1	oxide					594:598	graphene oxide	585:598	graphene oxide (GO)	585:603	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	8	69	theme	antibacterial	1267:1279	arg1	activity					1281:1288	antibacterial activity	1267:1288	antibacterial activity	1267:1288	Their cytotoxicity and antibacterial activity were more under light irradiation compared to the dark.					
35358565	7	70	theme	%	1173:1173	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	71	theme	˃	1174:1174	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	7	72	theme	5.0 wt	1167:1172	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	9	73	from	48 h	1466:1469	arg1	L929 cells					1474:1483	L929 cells	1474:1483	L929 cells	1474:1483	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	73	from	48 h	1466:1469	arg1	IZD					1515:1517	IZD	1515:1517	IZD	1515:1517	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	73	from	48 h	1466:1469	arg1	diameter					1505:1512	inhibition zone diameter	1489:1512	inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1489:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	7	74	theme	%	1164:1164	arg1	%					1191:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt%	1164:1191	%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions	1164:1210	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	3	75	theme	embedding	424:432	arg1	nanomaterials					438:450	the nanomaterials	434:450	embedding the nanomaterials into the NFs	424:463	The powdered form of nanomaterials can be aggregated while embedding the nanomaterials into the NFs can overcome the limitation and enhance the photocatalytic activity and transition from UV-light to visiblelight.					
35358565	5	76	theme	0.5 wt	846:851	arg1	%					852:852	0.5 wt%	846:852	0.5 wt%	846:852	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	0	77	theme	GO-graft-chitosan	33:49	arg1	nanofibers					61:70	GO-graft-chitosan composite nanofibers	33:70	GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance	33:143	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	9	78	theme	zone	1500:1503	arg1	IZD					1515:1517	IZD	1515:1517	IZD	1515:1517	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	78	theme	zone	1500:1503	arg1	diameter					1505:1512	inhibition zone diameter	1489:1512	inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1489:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	5	79	theme	5.0 wt	864:869	arg1	%					870:870	5.0 wt%	864:870	5.0 wt%	864:870	The blends of polyacrylonitrile (PAN) and AGC NPs were prepared in various concentrations of 0.5 wt%, 1.0 wt%, 5.0 wt%, and 10.0 wt% and used to fabricate the electrospun composite NFs.					
35358565	0	80	theme	visible	77:83	arg1	light					85:89	visible light	77:89	visible light photocatalytic activity	77:113	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	4	81	dep	oxide	594:598	arg1	GO					601:602	GO	601:602	GO	601:602	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	7	82	theme	light	1225:1229	arg1	irradiation					1231:1241	light irradiation	1225:1241	light irradiation	1225:1241	The cytotoxicity and antibacterial activity of the composite NFs were received in the order of composite NFs 10.0 wt%˃ 5.0 wt%˃ 1.0 wt%˃ 0.5 wt% in both conditions with/without light irradiation.					
35358565	2	83	theme	intrinsic	253:261	arg1	properties					277:286	intrinsic antibacterial properties	253:286	intrinsic antibacterial properties	253:286	The nanomaterials possessing both intrinsic antibacterial properties and photocatalytic activity are excellent candidates for water disinfection.					
35358565	9	84	theme	12 mm	1523:1527	arg1	L929 cells					1474:1483	L929 cells	1474:1483	L929 cells	1474:1483	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	84	theme	12 mm	1523:1527	arg1	IZD					1515:1517	IZD	1515:1517	IZD	1515:1517	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	84	theme	12 mm	1523:1527	arg1	diameter					1505:1512	inhibition zone diameter	1489:1512	inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1489:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	85	theme	composite	1350:1358	arg1	NFs					1360:1362	The composite NFs	1346:1362	The composite NFs (5.0 wt%)	1346:1372	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	85	theme	composite	1350:1358	arg1	%					1371:1371	5.0 wt%	1365:1371	5.0 wt%	1365:1371	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	9	85	theme	composite	1350:1358	arg1	NFs					1408:1410	the optimum NFs	1396:1410	the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation	1396:1602	The composite NFs (5.0 wt%) were distinguished as the optimum NFs with cell viability of 80% within 24 h and 60% within 48 h on L929 cells and inhibition zone diameter (IZD) of 12 mm for E. coli and 13 mm for S. aureus after 24 h under the light irradiation.					
35358565	4	86	theme	Ag	684:685	arg1	nanoparticles					669:681	silver nanoparticles	662:681	silver nanoparticles (Ag NPs)	662:690	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	4	86	theme	Ag	684:685	arg1	NPs					687:689	Ag NPs	684:689	Ag NPs	684:689	Here, graphene oxide (GO) was synthesized, grafted to chitosan, and decorated with silver nanoparticles (Ag NPs) to produce Ag-decorated reduced GO-graft-Chitosan (AGC) NPs.					
35358565	0	87	with	nanofibers	61:70	arg1	activity					106:113	visible light photocatalytic activity	77:113	visible light photocatalytic activity	77:113	Electrospun Ag-decorated reduced GO-graft-chitosan composite nanofibers with visible light photocatalytic activity for antibacterial performance.					
35358565	10	88	theme	composite	1617:1625	arg1	NFs					1627:1629	The optimum composite NFs	1605:1629	The optimum composite NFs	1605:1629	The optimum composite NFs showed thermal stability up to 180 °C and tensile strength of 1.11 MPa with 21.71% elongation at break.					
35491036	8	0	theme	practical	1338:1346	arg1	application					1348:1358	practical application	1338:1358	practical application	1338:1358	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	9	1	theme	applications	1484:1495	arg1	wide					1476:1479	a wide	1474:1479	a wide of applications	1474:1495	We believe that this work can provide a remarkable insight for the rational design of stimuli-responsive CPs for a wide of applications.					
35491036	2	2	theme	portable	358:365	arg1	immunoassay					367:377	a portable immunoassay	356:377	a portable immunoassay	356:377	In this work, we demonstrated the potential of stimuli-responsive CPs as a host of integrating enzymes to construct a portable immunoassay.					
35491036	8	3	theme	CEA	1287:1289	arg1	determination					1270:1282	The successful determination	1255:1282	The successful determination of CEA in serum samples	1255:1306	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	0	4	theme	portable	96:103	arg1	immunoassay					105:115	portable immunoassay	96:115	portable immunoassay	96:115	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	7	5	theme	PGM-based	1077:1085	arg1	immunoassay					1096:1106	a PGM-based portable immunoassay	1075:1106	a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA)	1075:1170	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	8	6	theme	successful	1259:1268	arg1	determination					1270:1282	The successful determination	1255:1282	The successful determination of CEA in serum samples	1255:1306	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	2	7	theme	CPs	306:308	arg1	potential					274:282	the potential	270:282	the potential of stimuli-responsive CPs as a host of integrating enzymes	270:341	In this work, we demonstrated the potential of stimuli-responsive CPs as a host of integrating enzymes to construct a portable immunoassay.					
35491036	9	8	theme	rational	1428:1435	arg1	design					1437:1442	the rational design	1424:1442	the rational design of stimuli-responsive CPs	1424:1468	We believe that this work can provide a remarkable insight for the rational design of stimuli-responsive CPs for a wide of applications.					
35491036	4	9	attach	isolated	713:720	arg2	GA					695:696	the loaded GA	684:696	the loaded GA	684:696	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	4	9	attach	isolated	713:720	arg1	starch					741:746	its substrate starch	727:746	its substrate starch	727:746	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	8	10	from	potential	1325:1333	arg1	application					1348:1358	practical application	1338:1358	practical application	1338:1358	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	3	11	dep	ion	401:403	arg1	Tb3+					406:409	Tb3+	406:409	Tb3+	406:409	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	2	12	theme	stimuli-responsive	287:304	arg1	CPs					306:308	stimuli-responsive CPs	287:308	stimuli-responsive CPs	287:308	In this work, we demonstrated the potential of stimuli-responsive CPs as a host of integrating enzymes to construct a portable immunoassay.					
35491036	2	13	theme	integrating	323:333	arg1	enzymes					335:341	integrating enzymes	323:341	integrating enzymes	323:341	In this work, we demonstrated the potential of stimuli-responsive CPs as a host of integrating enzymes to construct a portable immunoassay.					
35491036	5	14	from	composite	928:936	arg1	release					899:905	the release	895:905	the release of GA from GA@Tb/GMP composite	895:936	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	6	15	theme	personal	1023:1030	arg1	PGM					1047:1049	PGM	1047:1049	PGM	1047:1049	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	6	15	theme	personal	1023:1030	arg1	meter					1040:1044	personal glucose meter	1023:1044	personal glucose meter (PGM)	1023:1050	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	5	16	theme	phosphate	821:829	arg1	GMP					840:842	GMP	840:842	GMP	840:842	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	5	16	theme	phosphate	821:829	arg1	group					831:835	the phosphate group	817:835	the phosphate group of GMP to destroy the structure of Tb/GMP CPs	817:881	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	6	17	theme	released	943:950	arg1	GA					952:953	The released GA	939:953	The released GA	939:953	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	4	18	theme	loaded	688:693	arg1	GA					695:696	the loaded GA	684:696	the loaded GA	684:696	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	1	19	with	polymers	131:138	arg1	properties					174:183	properties	174:183	properties	174:183	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	1	19	with	polymers	131:138	arg1	structures					159:168	tunable structures	151:168	tunable structures	151:168	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	9	20	theme	remarkable	1401:1410	arg1	insight					1412:1418	a remarkable insight	1399:1418	a remarkable insight for the rational design of stimuli-responsive CPs	1399:1468	We believe that this work can provide a remarkable insight for the rational design of stimuli-responsive CPs for a wide of applications.					
35491036	0	21	theme	Integrated	0:9	arg1	enzyme					11:16	Integrated enzyme	0:16	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose	0:82	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	5	22	theme	Tb/GMP	921:926	arg1	composite					928:936	GA@Tb/GMP composite	918:936	GA@Tb/GMP composite	918:936	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	1	23	theme	Coordination	118:129	arg1	CPs					141:143	CPs	141:143	CPs	141:143	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	1	23	theme	Coordination	118:129	arg1	polymers					131:138	Coordination polymers	118:138	Coordination polymers (CPs) with tunable structures and properties	118:183	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	3	24	theme	metal	417:421	arg1	node					423:426	a metal node	415:426	a metal node	415:426	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	0	25	theme	stimuli-responsive	23:40	arg1	polymer					55:61	stimuli-responsive coordination polymer	23:61	stimuli-responsive coordination polymer	23:61	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	5	26	theme	GA	910:911	arg1	release					899:905	the release	895:905	the release of GA from GA@Tb/GMP composite	895:936	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	3	27	theme	-responsive	509:519	arg1	CPs					528:530	an alkaline phosphatase (ALP)-responsive Tb/GMP CPs	480:530	an alkaline phosphatase (ALP)-responsive Tb/GMP CPs	480:530	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	8	28	from	determination	1270:1282	arg1	samples					1300:1306	serum samples	1294:1306	serum samples	1294:1306	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	7	29	theme	antigen	1158:1164	arg1	analysis					1129:1136	the quantitative analysis	1112:1136	the quantitative analysis of carcinoembryonic antigen (CEA)	1112:1170	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	4	30	theme	CPs	669:671	arg1	size-selectivity					642:657	the size-selectivity	638:657	the size-selectivity of Tb/GMP CPs	638:671	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	5	31	theme	GMP	840:842	arg1	GMP					840:842	GMP	840:842	GMP	840:842	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	5	31	theme	GMP	840:842	arg1	group					831:835	the phosphate group	817:835	the phosphate group of GMP to destroy the structure of Tb/GMP CPs	817:881	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	3	32	theme	Tb/GMP	521:526	arg1	CPs					528:530	an alkaline phosphatase (ALP)-responsive Tb/GMP CPs	480:530	an alkaline phosphatase (ALP)-responsive Tb/GMP CPs	480:530	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	6	33	theme	measured	1004:1011	arg1	signal					1013:1018	a measured signal	1002:1018	a measured signal by personal glucose meter (PGM)	1002:1050	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	7	34	theme	carcinoembryonic	1141:1156	arg1	antigen					1158:1164	carcinoembryonic antigen	1141:1164	carcinoembryonic antigen (CEA)	1141:1170	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	7	34	theme	carcinoembryonic	1141:1156	arg1	CEA					1167:1169	CEA	1167:1169	CEA	1167:1169	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	5	35	theme	Tb/GMP	758:763	arg1	CPs					765:767	Tb/GMP CPs	758:767	Tb/GMP CPs	758:767	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	4	36	theme	substrate	731:739	arg1	starch					741:746	its substrate starch	727:746	its substrate starch	727:746	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	3	37	theme	guanine	432:438	arg1	monophosphate					440:452	guanine monophosphate	432:452	guanine monophosphate (GMP)	432:458	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	37	theme	guanine	432:438	arg1	ion					401:403	terbium ion	393:403	terbium ion (Tb3+) as a metal node	393:426	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	37	theme	guanine	432:438	arg1	ligand					472:477	a bridge ligand	463:477	a bridge ligand	463:477	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	37	theme	guanine	432:438	arg1	GMP					455:457	GMP	455:457	GMP	455:457	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	0	38	theme	coordination	42:53	arg1	polymer					55:61	stimuli-responsive coordination polymer	23:61	stimuli-responsive coordination polymer	23:61	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	7	39	theme	0.28 ng/mL	1224:1233	arg1	limit					1215:1219	a detection limit	1203:1219	a detection limit of 0.28 ng/mL	1203:1233	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	1	40	theme	fields	232:237	arg1	variety					221:227	a variety	219:227	a variety of fields	219:237	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	1	40	theme	fields	232:237	arg1	fields					232:237	fields	232:237	fields	232:237	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	0	41	theme	personal	67:74	arg1	glucose					76:82	personal glucose	67:82	personal glucose	67:82	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	8	42	theme	serum	1294:1298	arg1	samples					1300:1306	serum samples	1294:1306	serum samples	1294:1306	The successful determination of CEA in serum samples demonstrates its potential in practical application.					
35491036	7	43	theme	detection	1205:1213	arg1	limit					1215:1219	a detection limit	1203:1219	a detection limit of 0.28 ng/mL	1203:1233	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	7	44	theme	quantitative	1116:1127	arg1	analysis					1129:1136	the quantitative analysis	1112:1136	the quantitative analysis of carcinoembryonic antigen (CEA)	1112:1170	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	6	45	theme	glucose	1032:1038	arg1	PGM					1047:1049	PGM	1047:1049	PGM	1047:1049	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	6	45	theme	glucose	1032:1038	arg1	meter					1040:1044	personal glucose meter	1023:1044	personal glucose meter (PGM)	1023:1050	The released GA can digest starch to produce glucoses and give a measured signal by personal glucose meter (PGM).					
35491036	3	46	theme	@	610:610	arg1	composite					618:626	GA@Tb/GMP composite	608:626	GA@Tb/GMP composite	608:626	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	5	47	theme	GA	918:919	arg1	composite					928:936	GA@Tb/GMP composite	918:936	GA@Tb/GMP composite	918:936	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	0	48	with	enzyme	11:16	arg1	polymer					55:61	stimuli-responsive coordination polymer	23:61	stimuli-responsive coordination polymer	23:61	Integrated enzyme with stimuli-responsive coordination polymer for personal glucose meter-based portable immunoassay.					
35491036	3	49	theme	bridge	465:470	arg1	monophosphate					440:452	guanine monophosphate	432:452	guanine monophosphate (GMP)	432:458	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	49	theme	bridge	465:470	arg1	ion					401:403	terbium ion	393:403	terbium ion (Tb3+) as a metal node	393:426	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	49	theme	bridge	465:470	arg1	ligand					472:477	a bridge ligand	463:477	a bridge ligand	463:477	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	9	50	theme	stimuli-responsive	1447:1464	arg1	CPs					1466:1468	stimuli-responsive CPs	1447:1468	stimuli-responsive CPs	1447:1468	We believe that this work can provide a remarkable insight for the rational design of stimuli-responsive CPs for a wide of applications.					
35491036	3	51	theme	Tb/GMP	611:616	arg1	composite					618:626	GA@Tb/GMP composite	608:626	GA@Tb/GMP composite	608:626	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	5	52	theme	CPs	879:881	arg1	structure					859:867	the structure	855:867	the structure of Tb/GMP CPs	855:881	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	2	53	theme	enzymes	335:341	arg1	host					315:318	a host	313:318	a host of integrating enzymes	313:341	In this work, we demonstrated the potential of stimuli-responsive CPs as a host of integrating enzymes to construct a portable immunoassay.					
35491036	5	54	theme	Tb/GMP	872:877	arg1	CPs					879:881	Tb/GMP CPs	872:881	Tb/GMP CPs	872:881	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	5	55	theme	@	920:920	arg1	composite					928:936	GA@Tb/GMP composite	918:936	GA@Tb/GMP composite	918:936	However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite.					
35491036	1	56	theme	tunable	151:157	arg1	structures					159:168	tunable structures	151:168	tunable structures	151:168	Coordination polymers (CPs) with tunable structures and properties have been extensively explored in a variety of fields.					
35491036	4	57	theme	Tb/GMP	662:667	arg1	CPs					669:671	Tb/GMP CPs	662:671	Tb/GMP CPs	662:671	Owing to the size-selectivity of Tb/GMP CPs as a host, the loaded GA was physically isolated from its substrate starch.					
35491036	3	58	theme	GA	608:609	arg1	composite					618:626	GA@Tb/GMP composite	608:626	GA@Tb/GMP composite	608:626	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	7	59	theme	satisfactory	1177:1188	arg1	results					1190:1196	satisfactory results	1177:1196	satisfactory results with a detection limit of 0.28 ng/mL	1177:1233	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	7	60	theme	portable	1087:1094	arg1	immunoassay					1096:1106	a PGM-based portable immunoassay	1075:1106	a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA)	1075:1170	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	3	61	theme	terbium	393:399	arg1	monophosphate					440:452	guanine monophosphate	432:452	guanine monophosphate (GMP)	432:458	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	61	theme	terbium	393:399	arg1	ion					401:403	terbium ion	393:403	terbium ion (Tb3+) as a metal node	393:426	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	61	theme	terbium	393:399	arg1	ligand					472:477	a bridge ligand	463:477	a bridge ligand	463:477	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	7	62	with	results	1190:1196	arg1	limit					1215:1219	a detection limit	1203:1219	a detection limit of 0.28 ng/mL	1203:1233	This finding leads to a PGM-based portable immunoassay for the quantitative analysis of carcinoembryonic antigen (CEA), and satisfactory results with a detection limit of 0.28 ng/mL have been achieved.					
35491036	3	63	theme	alkaline	483:490	arg1	ALP					505:507	ALP	505:507	ALP	505:507	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	3	63	theme	alkaline	483:490	arg1	phosphatase					492:502	alkaline phosphatase	483:502	alkaline phosphatase (ALP)	483:508	By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite.					
35491036	9	64	theme	CPs	1466:1468	arg1	design					1437:1442	the rational design	1424:1442	the rational design of stimuli-responsive CPs	1424:1468	We believe that this work can provide a remarkable insight for the rational design of stimuli-responsive CPs for a wide of applications.					
35757971	7	0	theme	base	1150:1153	arg1	reaction					1155:1162	the Schiff base reaction	1139:1162	the Schiff base reaction between OSA and SF	1139:1181	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	9	1	theme	composite	1327:1335	arg1	scaffolds					1337:1345	the composite scaffolds	1323:1345	the composite scaffolds	1323:1345	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	1	2	theme	therapy	170:176	arg1	source					151:156	a prospective source	137:156	a prospective source of advanced therapy in repairing severe traumatic wounds	137:213	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	0	3	theme	tissue	78:83	arg1	engineering					85:95	skin tissue engineering	73:95	skin tissue engineering	73:95	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	2	4	theme	other	333:337	arg1	fields					339:344	other fields	333:344	other fields	333:344	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	5	5	used	used	814:817	arg2	oxidant					822:828	oxidant	822:828	oxidant	822:828	Sodium periodate was used as oxidant to modify SA.					
35757971	5	5	used	used	814:817	arg2	periodate					800:808	Sodium periodate	793:808	Sodium periodate	793:808	Sodium periodate was used as oxidant to modify SA.					
35757971	7	6	theme	Schiff	1143:1148	arg1	reaction					1155:1162	the Schiff base reaction	1139:1162	the Schiff base reaction between OSA and SF	1139:1181	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	7	7	theme	composite	1044:1052	arg1	scaffolds					1054:1062	The composite scaffolds	1040:1062	The composite scaffolds	1040:1062	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	9	8	theme	good	1442:1445	arg1	biocompatibility					1447:1462	good biocompatibility	1442:1462	good biocompatibility	1442:1462	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	9	9	contain	had	1438:1440	arg1	scaffolds					1428:1436	the composite scaffolds	1414:1436	the composite scaffolds	1414:1436	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	9	9	contain	had	1438:1440	arg2	biocompatibility					1447:1462	good biocompatibility	1442:1462	good biocompatibility	1442:1462	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	8	10	theme	base	1216:1219	arg1	group					1221:1225	the Schiff base group	1205:1225	the Schiff base group	1205:1225	FT-IR confirmed that the Schiff base group appeared in the material.					
35757971	2	11	theme	natural	263:269	arg1	biomaterials					271:282	natural biomaterials	263:282	natural biomaterials	263:282	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	11	theme	natural	263:269	arg1	alginate					223:230	Sodium alginate	216:230	Sodium alginate (SA)	216:235	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	11	theme	natural	263:269	arg1	fibroin					246:252	silk fibroin	241:252	silk fibroin (SF)	241:257	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	1	12	theme	traumatic	198:206	arg1	wounds					208:213	severe traumatic wounds	191:213	severe traumatic wounds	191:213	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	9	13	theme	cytocompatibility	1373:1389	arg1	experiment					1391:1400	the cytocompatibility experiment	1369:1400	the cytocompatibility experiment	1369:1400	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	3	14	dep	degradation	454:464	arg1	products					516:523	the degradation products	500:523	the degradation products	500:523	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	3	14	dep	degradation	454:464	arg1	difficult					474:482	difficult	474:482	difficult	474:482	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	3	14	dep	degradation	454:464	arg1	difficult					529:537	difficult	529:537	difficult	529:537	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	1	15	theme	severe	191:196	arg1	wounds					208:213	severe traumatic wounds	191:213	severe traumatic wounds	191:213	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	0	16	theme	sodium	9:14	arg1	alginate					16:23	Oxidized sodium alginate	0:23	Oxidized sodium alginate	0:23	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	7	17	theme	reaction	1155:1162	arg1	accelerator					1124:1134	a crosslinking accelerator	1109:1134	a crosslinking accelerator of the Schiff base reaction between OSA and SF	1109:1181	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	7	17	theme	reaction	1155:1162	arg1	tetraborate					1094:1104	sodium tetraborate	1087:1104	sodium tetraborate	1087:1104	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	6	18	theme	oxidized	999:1006	arg1	products					1008:1015	the oxidized products	995:1015	the oxidized products	995:1015	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	2	19	theme	low	363:365	arg1	price					367:371	their low price	357:371	their low price	357:371	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	0	20	theme	Oxidized	0:7	arg1	alginate					16:23	Oxidized sodium alginate	0:23	Oxidized sodium alginate	0:23	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	9	21	theme	In	1253:1254	arg1	experiments					1277:1287	In vitro biodegradation experiments	1253:1287	In vitro biodegradation experiments	1253:1287	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	1	22	theme	Engineering	98:108	arg1	skin					110:113	Engineering skin substitutes	98:125	Engineering skin substitutes	98:125	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	6	23	theme	products	1008:1015	arg1	weight					985:990	the relative molecular weight	962:990	the relative molecular weight of the oxidized products	962:1015	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	3	24	theme	degradation	504:514	arg1	products					516:523	the degradation products	500:523	the degradation products	500:523	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	3	24	theme	degradation	504:514	arg1	difficult					529:537	difficult	529:537	difficult	529:537	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	9	25	theme	composite	1418:1426	arg1	scaffolds					1428:1436	the composite scaffolds	1414:1436	the composite scaffolds	1414:1436	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	2	26	theme	good	391:394	arg1	biocompatibility					396:411	good biocompatibility	391:411	good biocompatibility	391:411	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	4	27	theme	Schiff	701:706	arg1	reaction					713:720	the Schiff base reaction	697:720	the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA)	697:790	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	5	28	theme	Sodium	793:798	arg1	periodate					800:808	Sodium periodate	793:808	Sodium periodate	793:808	Sodium periodate was used as oxidant to modify SA.					
35757971	5	28	theme	Sodium	793:798	arg1	oxidant					822:828	oxidant	822:828	oxidant	822:828	Sodium periodate was used as oxidant to modify SA.					
35757971	0	29	theme	fibroin	42:48	arg1	scaffold					60:67	silk fibroin composite scaffold	37:67	silk fibroin composite scaffold for skin tissue engineering	37:95	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	4	30	theme	composite	616:624	arg1	scaffolds					626:634	the composite scaffolds	612:634	the composite scaffolds	612:634	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	7	31	theme	crosslinking	1111:1122	arg1	accelerator					1124:1134	a crosslinking accelerator	1109:1134	a crosslinking accelerator of the Schiff base reaction between OSA and SF	1109:1181	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	7	31	theme	crosslinking	1111:1122	arg1	tetraborate					1094:1104	sodium tetraborate	1087:1104	sodium tetraborate	1087:1104	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	2	32	theme	silk	241:244	arg1	biomaterials					271:282	natural biomaterials	263:282	natural biomaterials	263:282	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	32	theme	silk	241:244	arg1	alginate					223:230	Sodium alginate	216:230	Sodium alginate (SA)	216:235	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	32	theme	silk	241:244	arg1	SF					255:256	SF	255:256	SF	255:256	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	32	theme	silk	241:244	arg1	fibroin					246:252	silk fibroin	241:252	silk fibroin (SF)	241:257	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	6	33	theme	molecular	975:983	arg1	weight					985:990	the relative molecular weight	962:990	the relative molecular weight of the oxidized products	962:1015	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	0	34	theme	silk	37:40	arg1	scaffold					60:67	silk fibroin composite scaffold	37:67	silk fibroin composite scaffold for skin tissue engineering	37:95	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	6	35	theme	OSA	895:897	arg1	degree					885:890	higher oxidation degree	868:890	higher oxidation degree of OSA	868:897	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	7	36	theme	sodium	1087:1092	arg1	accelerator					1124:1134	a crosslinking accelerator	1109:1134	a crosslinking accelerator of the Schiff base reaction between OSA and SF	1109:1181	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	7	36	theme	sodium	1087:1092	arg1	tetraborate					1094:1104	sodium tetraborate	1087:1104	sodium tetraborate	1087:1104	The composite scaffolds were prepared by using sodium tetraborate as a crosslinking accelerator of the Schiff base reaction between OSA and SF.					
35757971	3	37	theme	high	578:581	arg1	weight					593:598	its high molecular weight	574:598	its high molecular weight	574:598	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	9	38	theme	biodegradation	1262:1275	arg1	experiments					1277:1287	In vitro biodegradation experiments	1253:1287	In vitro biodegradation experiments	1253:1287	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	2	39	theme	high	374:377	arg1	safety					379:384	high safety	374:384	high safety	374:384	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	9	40	dep	In	1253:1254	arg1	vitro					1256:1260	vitro	1256:1260	vitro	1256:1260	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	3	41	theme	molecular	583:591	arg1	weight					593:598	its high molecular weight	574:598	its high molecular weight	574:598	However, SA itself degrades slowly, its degradation mode is difficult to control, and the degradation products are difficult to remove from the body because of its high molecular weight.					
35757971	4	42	theme	composite	667:675	arg1	technology					677:686	freeze-drying composite technology	653:686	freeze-drying composite technology	653:686	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	0	43	theme	composite	50:58	arg1	scaffold					60:67	silk fibroin composite scaffold	37:67	silk fibroin composite scaffold for skin tissue engineering	37:95	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	4	44	theme	freeze-drying	653:665	arg1	technology					677:686	freeze-drying composite technology	653:686	freeze-drying composite technology	653:686	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	6	45	theme	oxidation	875:883	arg1	degree					885:890	higher oxidation degree	868:890	higher oxidation degree of OSA	868:897	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	8	46	theme	Schiff	1209:1214	arg1	group					1221:1225	the Schiff base group	1205:1225	the Schiff base group	1205:1225	FT-IR confirmed that the Schiff base group appeared in the material.					
35757971	4	47	theme	permeable	751:759	arg1	OSA					787:789	OSA	787:789	OSA	787:789	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	4	47	theme	permeable	751:759	arg1	alginate					777:784	permeable oxidized sodium alginate	751:784	permeable oxidized sodium alginate (OSA)	751:790	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	1	48	theme	prospective	139:149	arg1	source					151:156	a prospective source	137:156	a prospective source of advanced therapy in repairing severe traumatic wounds	137:213	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	4	49	theme	base	708:711	arg1	reaction					713:720	the Schiff base reaction	697:720	the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA)	697:790	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	4	50	theme	biocompatible	730:742	arg1	SF					744:745	biocompatible SF	730:745	biocompatible SF	730:745	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	2	51	theme	Sodium	216:221	arg1	biomaterials					271:282	natural biomaterials	263:282	natural biomaterials	263:282	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	51	theme	Sodium	216:221	arg1	SA					233:234	SA	233:234	SA	233:234	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	51	theme	Sodium	216:221	arg1	alginate					223:230	Sodium alginate	216:230	Sodium alginate (SA)	216:235	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	51	theme	Sodium	216:221	arg1	fibroin					246:252	silk fibroin	241:252	silk fibroin (SF)	241:257	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	52	theme	tissue	310:315	arg1	engineering					317:327	tissue engineering	310:327	tissue engineering	310:327	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	0	53	theme	skin	73:76	arg1	engineering					85:95	skin tissue engineering	73:95	skin tissue engineering	73:95	Oxidized sodium alginate crosslinked silk fibroin composite scaffold for skin tissue engineering.					
35757971	6	54	theme	relative	966:973	arg1	weight					985:990	the relative molecular weight	962:990	the relative molecular weight of the oxidized products	962:1015	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	4	55	theme	sodium	770:775	arg1	OSA					787:789	OSA	787:789	OSA	787:789	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	4	55	theme	sodium	770:775	arg1	alginate					777:784	permeable oxidized sodium alginate	751:784	permeable oxidized sodium alginate (OSA)	751:790	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	1	56	dep	skin	110:113	arg1	substitutes					115:125	substitutes	115:125	substitutes	115:125	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	2	57	used	used	302:305	arg2	alginate					223:230	Sodium alginate	216:230	Sodium alginate (SA)	216:235	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	57	used	used	302:305	arg2	fibroin					246:252	silk fibroin	241:252	silk fibroin (SF)	241:257	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	2	57	used	used	302:305	arg2	biomaterials					271:282	natural biomaterials	263:282	natural biomaterials	263:282	Sodium alginate (SA) and silk fibroin (SF) are natural biomaterials, which are widely used in tissue engineering and other fields because of their low price, high safety, and good biocompatibility.					
35757971	9	58	theme	scaffolds	1337:1345	arg1	biodegradation					1305:1318	the biodegradation	1301:1318	the biodegradation of the composite scaffolds	1301:1345	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	9	58	theme	scaffolds	1337:1345	arg1	controllable					1351:1362	controllable	1351:1362	controllable	1351:1362	In vitro biodegradation experiments showed that the biodegradation of the composite scaffolds was controllable, and the cytocompatibility experiment showed that the composite scaffolds had good biocompatibility.					
35757971	6	59	theme	higher	868:873	arg1	degree					885:890	higher oxidation degree	868:890	higher oxidation degree of OSA	868:897	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35757971	4	60	theme	oxidized	761:768	arg1	OSA					787:789	OSA	787:789	OSA	787:789	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	4	60	theme	oxidized	761:768	arg1	alginate					777:784	permeable oxidized sodium alginate	751:784	permeable oxidized sodium alginate (OSA)	751:790	Therefore, the composite scaffolds were prepared by freeze-drying composite technology by using the Schiff base reaction between biocompatible SF and permeable oxidized sodium alginate (OSA).					
35757971	1	61	theme	advanced	161:168	arg1	therapy					170:176	advanced therapy	161:176	advanced therapy	161:176	Engineering skin substitutes represent a prospective source of advanced therapy in repairing severe traumatic wounds.					
35757971	6	62	theme	oxidant	949:955	arg1	proportion					935:944	the proportion	931:944	the proportion of oxidant	931:955	The results showed that higher oxidation degree of OSA could be obtained by increasing the proportion of oxidant, and the relative molecular weight of the oxidized products could also be reduced.					
35997096	0	0	from	Studies	16:22	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	0	from	Studies	16:22	arg1	Production					104:113	Its Production	100:113	Its Production of Phenol Compounds	100:133	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	0	from	Studies	16:22	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	7	1	theme	phenol	1211:1216	arg1	compounds					1218:1226	the phenol compounds	1207:1226	the phenol compounds	1207:1226	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	0	2	theme	Various	141:147	arg1	Conditions					161:170	Various Cultivation Conditions	141:170	Various Cultivation Conditions	141:170	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	6	3	contain	have	1039:1042	arg1	pH					1007:1008	The initial pH	995:1008	The initial pH of cultivated medium	995:1029	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	6	3	contain	have	1039:1042	arg2	influence					1052:1060	a large influence	1044:1060	a large influence on phenol compound production	1044:1090	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	8	4	theme	sparassol	1471:1479	arg1	producer					1481:1488	a promising sparassol producer	1459:1488	a promising sparassol producer	1459:1488	Strain LE-BIN 2902 is considered a promising sparassol producer.					
35997096	5	5	located	detected	801:808	arg1	duration					945:952	duration	945:952	duration	945:952	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	5	located	detected	801:808	arg1	acidity					933:939	different acidity	923:939	different acidity	923:939	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	5	located	detected	801:808	arg2	compounds					786:794	Phenol compounds	779:794	Phenol compounds	779:794	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	5	located	detected	801:808	arg1	mycelium					822:829	mycelium	822:829	mycelium	822:829	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	5	located	detected	801:808	arg1	filtrate					843:850	culture filtrate	835:850	culture filtrate	835:850	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	4	6	theme	sparassol	693:701	arg1	ester					714:718	methyl ester	707:718	methyl ester of orsellinic acid	707:737	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	4	6	theme	sparassol	693:701	arg1	ester					684:688	methyl ester	677:688	methyl ester of sparassol	677:701	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	1	7	theme	phenol	345:350	arg1	production					361:370	phenol compound production	345:370	phenol compound production	345:370	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	3	8	theme	gas	520:522	arg1	spectrometry					544:555	gas chromatography-mass spectrometry	520:555	gas chromatography-mass spectrometry	520:555	Using gas chromatography-mass spectrometry, the crystals were identified as sparassol (methyl 2-hydroxy-4-methoxy-6-methylbenzoate).					
35997096	6	9	theme	culture	1100:1106	arg1	duration					1115:1122	culture growth duration	1100:1122	culture growth duration	1100:1122	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	2	10	theme	naked	503:507	arg1	eye					509:511	the naked eye	499:511	the naked eye	499:511	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	1	11	theme	compound	352:359	arg1	production					361:370	phenol compound production	345:370	phenol compound production	345:370	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	7	12	theme	compounds	1218:1226	arg1	Production					1193:1202	Production	1193:1202	Production of the phenol compounds	1193:1226	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	3	13	theme	chromatography-mass	524:542	arg1	spectrometry					544:555	gas chromatography-mass spectrometry	520:555	gas chromatography-mass spectrometry	520:555	Using gas chromatography-mass spectrometry, the crystals were identified as sparassol (methyl 2-hydroxy-4-methoxy-6-methylbenzoate).					
35997096	7	14	from	production	1329:1338	arg1	mycelium					1360:1367	mycelium	1360:1367	mycelium	1360:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	7	15	theme	constitutive	1254:1265	arg1	processes					1267:1275	constitutive processes	1254:1275	constitutive processes of Sparassis metabolism	1254:1299	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	6	16	theme	cultivated	1013:1022	arg1	medium					1024:1029	cultivated medium	1013:1029	cultivated medium	1013:1029	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	4	17	theme	crispa	762:767	arg1	mycelium					769:776	S. crispa mycelium	759:776	S. crispa mycelium	759:776	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	4	18	theme	methyl	677:682	arg1	ester					684:688	methyl ester	677:688	methyl ester of sparassol	677:701	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	6	19	theme	sparassol	1156:1164	arg1	concentration					1166:1178	sparassol concentration	1156:1178	sparassol concentration in mycelium	1156:1190	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	2	20	theme	ultraviolet	461:471	arg1	light					473:477	ultraviolet light	461:477	ultraviolet light	461:477	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	6	21	theme	growth	1108:1113	arg1	duration					1115:1122	culture growth duration	1100:1122	culture growth duration	1100:1122	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	4	22	theme	S.	759:760	arg1	mycelium					769:776	S. crispa mycelium	759:776	S. crispa mycelium	759:776	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	6	23	theme	large	1046:1050	arg1	influence					1052:1060	a large influence	1044:1060	a large influence on phenol compound production	1044:1090	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	2	24	theme	sizes	440:444	arg1	crystals					409:416	crystals	409:416	crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye	409:511	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	7	25	theme	cultivation	1408:1418	arg1	time					1420:1423	cultivation time	1408:1423	cultivation time	1408:1423	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	7	26	from	intensity	1310:1318	arg1	mycelium					1360:1367	mycelium	1360:1367	mycelium	1360:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	1	27	theme	Sparassis	179:187	arg1	strains					196:202	Three Sparassis crispa strains	173:202	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	173:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	4	28	located	found	750:754	arg1	mycelium					769:776	S. crispa mycelium	759:776	S. crispa mycelium	759:776	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	4	28	located	found	750:754	arg2	compounds					660:668	Other phenol compounds	647:668	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid)	647:738	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	8	29	theme	promising	1461:1469	arg1	producer					1481:1488	a promising sparassol producer	1459:1488	a promising sparassol producer	1459:1488	Strain LE-BIN 2902 is considered a promising sparassol producer.					
35997096	4	30	theme	acid	734:737	arg1	ester					714:718	methyl ester	707:718	methyl ester of orsellinic acid	707:737	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	4	30	theme	acid	734:737	arg1	ester					684:688	methyl ester	677:688	methyl ester of sparassol	677:701	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	7	31	theme	metabolism	1290:1299	arg1	processes					1267:1275	constitutive processes	1254:1275	constitutive processes of Sparassis metabolism	1254:1299	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	1	32	theme	crispa	189:194	arg1	strains					196:202	Three Sparassis crispa strains	173:202	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	173:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	2	33	theme	shapes	429:434	arg1	crystals					409:416	crystals	409:416	crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye	409:511	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	7	34	from	accumulation	1344:1355	arg1	mycelium					1360:1367	mycelium	1360:1367	mycelium	1360:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	5	35	theme	different	923:931	arg1	acidity					933:939	different acidity	923:939	different acidity	923:939	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	4	36	theme	Other	647:651	arg1	compounds					660:668	Other phenol compounds	647:668	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid)	647:738	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	2	37	theme	various	421:427	arg1	shapes					429:434	various shapes	421:434	various shapes	421:434	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	5	38	theme	liquid	906:911	arg1	media					913:917	various agar and liquid media	889:917	media	913:917	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	1	39	dep	Basidiomycetes	241:254	arg1	LE-BIN					276:281	LE-BIN	276:281	LE-BIN	276:281	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	1	39	dep	Basidiomycetes	241:254	arg1	Collection					264:273	Culture Collection	256:273	the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	209:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	5	40	theme	various	889:895	arg1	agar					897:900	various agar and liquid media	889:917	agar	897:900	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	4	41	dep	ester	684:688	arg1	i.e.					671:674	i.e.	671:674	i.e.	671:674	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	6	42	theme	phenol	1065:1070	arg1	production					1081:1090	phenol compound production	1065:1090	phenol compound production	1065:1090	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	0	43	theme	Medicinal	32:40	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	43	theme	Medicinal	32:40	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	1	44	theme	various	300:306	arg1	agar					308:311	various agar and liquid media	300:328	agar	308:311	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	0	45	theme	Compounds	125:133	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	45	theme	Compounds	125:133	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	45	theme	Compounds	125:133	arg1	Production					104:113	Its Production	100:113	Its Production of Phenol Compounds	100:133	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	8	46	theme	Strain	1426:1431	arg1	LE-BIN					1433:1438	Strain LE-BIN 2902	1426:1443	Strain LE-BIN 2902	1426:1443	Strain LE-BIN 2902 is considered a promising sparassol producer.					
35997096	2	47	theme	agar	376:379	arg1	media					381:385	agar media	376:385	agar media	376:385	On agar media, the strains produced crystals of various shapes and sizes that glowed in ultraviolet light and were visible to the naked eye.					
35997096	7	48	theme	Sparassis	1280:1288	arg1	metabolism					1290:1299	Sparassis metabolism	1280:1299	Sparassis metabolism	1280:1299	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	0	49	theme	Rare	27:30	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	49	theme	Rare	27:30	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	50	theme	Phenol	118:123	arg1	Compounds					125:133	Phenol Compounds	118:133	Phenol Compounds	118:133	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	5	51	theme	culture	835:841	arg1	filtrate					843:850	culture filtrate	835:850	culture filtrate	835:850	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	1	52	theme	Komarov	213:219	arg1	Basidiomycetes					241:254	the Komarov Botanical Institute Basidiomycetes	209:254	the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	209:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	0	53	theme	Sparassis	51:59	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	53	theme	Sparassis	51:59	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	1	54	from	Basidiomycetes	241:254	arg1	strains					196:202	Three Sparassis crispa strains	173:202	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	173:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	0	55	from	crispa	61:66	arg1	Culture					88:94	Culture	88:94	Culture	88:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	56	theme	Mushroom	42:49	arg1	Agaricomycetes					69:82	Agaricomycetes	69:82	Agaricomycetes	69:82	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	0	56	theme	Mushroom	42:49	arg1	crispa					61:66	Rare Medicinal Mushroom Sparassis crispa	27:66	Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture	27:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	1	57	theme	liquid	317:322	arg1	media					324:328	various agar and liquid media	300:328	media	324:328	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	5	58	dep	mycelium	822:829	arg1	the					818:820	the	818:820	the	818:820	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	58	dep	mycelium	822:829	arg1	both					810:813	both	810:813	both	810:813	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	4	59	theme	methyl	707:712	arg1	ester					714:718	methyl ester	707:718	methyl ester of orsellinic acid	707:737	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	3	60	theme	methyl	601:606	arg1	sparassol					590:598	sparassol	590:598	sparassol (methyl 2-hydroxy-4-methoxy-6-methylbenzoate)	590:644	Using gas chromatography-mass spectrometry, the crystals were identified as sparassol (methyl 2-hydroxy-4-methoxy-6-methylbenzoate).					
35997096	3	60	theme	methyl	601:606	arg1	2-hydroxy-4-methoxy-6-methylbenzoate					608:643	methyl 2-hydroxy-4-methoxy-6-methylbenzoate	601:643	methyl 2-hydroxy-4-methoxy-6-methylbenzoate	601:643	Using gas chromatography-mass spectrometry, the crystals were identified as sparassol (methyl 2-hydroxy-4-methoxy-6-methylbenzoate).					
35997096	7	61	theme	accumulation	1344:1355	arg1	intensity					1310:1318	the intensity	1306:1318	the intensity of their production and accumulation in mycelium	1306:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	4	62	theme	orsellinic	723:732	arg1	acid					734:737	orsellinic acid	723:737	orsellinic acid	723:737	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	5	63	theme	studied	859:865	arg1	strains					867:873	all studied strains	855:873	all studied strains cultivated on various agar and liquid media	855:917	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	1	64	theme	Botanical	221:229	arg1	Basidiomycetes					241:254	the Komarov Botanical Institute Basidiomycetes	209:254	the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	209:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	0	65	theme	Cultivation	149:159	arg1	Conditions					161:170	Various Cultivation Conditions	141:170	Various Cultivation Conditions	141:170	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	7	66	from	mycelium	1360:1367	arg1	intensity					1310:1318	the intensity	1306:1318	the intensity of their production and accumulation in mycelium	1306:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	6	67	from	influence	1052:1060	arg1	production					1081:1090	phenol compound production	1065:1090	phenol compound production	1065:1090	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	6	68	theme	compound	1072:1079	arg1	production					1081:1090	phenol compound production	1065:1090	phenol compound production	1065:1090	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	1	69	theme	Institute	231:239	arg1	Basidiomycetes					241:254	the Komarov Botanical Institute Basidiomycetes	209:254	the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	209:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	4	70	theme	phenol	653:658	arg1	compounds					660:668	Other phenol compounds	647:668	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid)	647:738	Other phenol compounds (i.e., methyl ester of sparassol and methyl ester of orsellinic acid) were also found in S. crispa mycelium.					
35997096	7	71	theme	production	1329:1338	arg1	intensity					1310:1318	the intensity	1306:1318	the intensity of their production and accumulation in mycelium	1306:1367	Production of the phenol compounds presumably connected with constitutive processes of Sparassis metabolism, but the intensity of their production and accumulation in mycelium depends on the strain, conditions, and cultivation time.					
35997096	6	72	theme	medium	1024:1029	arg1	pH					1007:1008	The initial pH	995:1008	The initial pH of cultivated medium	995:1029	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	5	73	theme	strains	867:873	arg1	mycelium					822:829	mycelium	822:829	mycelium	822:829	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	73	theme	strains	867:873	arg1	filtrate					843:850	culture filtrate	835:850	culture filtrate	835:850	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	5	74	theme	Phenol	779:784	arg1	compounds					786:794	Phenol compounds	779:794	Phenol compounds	779:794	Phenol compounds were detected both in the mycelium and culture filtrate of all studied strains cultivated on various agar and liquid media, at different acidity and duration, but their composition and ratio varied.					
35997096	0	75	from	Production	104:113	arg1	Culture					88:94	Culture	88:94	Culture	88:94	Contribution to Studies on Rare Medicinal Mushroom Sparassis crispa (Agaricomycetes) in Culture and Its Production of Phenol Compounds under Various Cultivation Conditions.					
35997096	6	76	theme	initial	999:1005	arg1	pH					1007:1008	The initial pH	995:1008	The initial pH of cultivated medium	995:1029	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	6	77	from	concentration	1166:1178	arg1	mycelium					1183:1190	mycelium	1183:1190	mycelium	1183:1190	The initial pH of cultivated medium did not have a large influence on phenol compound production, unlike culture growth duration, which correlated directly with sparassol concentration in mycelium.					
35997096	1	78	theme	Culture	256:262	arg1	LE-BIN					276:281	LE-BIN	276:281	LE-BIN	276:281	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
35997096	1	78	theme	Culture	256:262	arg1	Collection					264:273	Culture Collection	256:273	the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN)	209:282	Three Sparassis crispa strains from the Komarov Botanical Institute Basidiomycetes Culture Collection (LE-BIN) were studied on various agar and liquid media for growth and phenol compound production.					
36876790	0	0	theme	hydrostatic	75:85	arg1	extraction					105:114	high hydrostatic pressure-assisted extraction	70:114	high hydrostatic pressure-assisted extraction	70:114	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	7	1	theme	compression	1173:1183	arg1	tests					1185:1189	compression tests	1173:1189	compression tests	1173:1189	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	6	2	from	gelation	1049:1056	arg1	solutions					1067:1075	CaCl2 solutions	1061:1075	CaCl2 solutions	1061:1075	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	6	3	theme	external	1040:1047	arg1	gelation					1049:1056	external gelation	1040:1056	external gelation in CaCl2 solutions	1040:1075	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	0	4	theme	high	70:73	arg1	extraction					105:114	high hydrostatic pressure-assisted extraction	70:114	high hydrostatic pressure-assisted extraction	70:114	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	6	5	theme	alginate	1000:1007	arg1	extracts					1009:1016	the alginate extracts	996:1016	the alginate extracts	996:1016	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	8	6	theme	stiffer	1424:1430	arg1	conformation					1441:1452	the stiffer rod-like conformation	1420:1452	the stiffer rod-like conformation	1420:1452	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	7	7	theme	angle	1210:1214	arg1	SAXS					1234:1237	SAXS	1234:1237	SAXS	1234:1237	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	7	theme	angle	1210:1214	arg1	scattering					1222:1231	synchrotron small angle X-ray scattering	1192:1231	synchrotron small angle X-ray scattering (SAXS)	1192:1238	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	1	8	theme	recalcitrant	244:255	arg1	nature					257:262	the recalcitrant nature	240:262	the recalcitrant nature of two algae species	240:283	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	8	9	theme	SHP	1372:1374	arg1	strength					1360:1367	the gel strength	1352:1367	the gel strength of SHP	1352:1374	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	2	10	dep	structure	347:355	arg1	SEC-MALS					380:387	SEC-MALS	380:387	SEC-MALS	380:387	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	2	10	dep	structure	347:355	arg1	NMR					375:377	NMR	375:377	NMR	375:377	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	2	10	dep	structure	347:355	arg1	FTIR					369:372	FTIR	369:372	FTIR	369:372	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	2	10	dep	structure	347:355	arg1	HPAEC-PAD					358:366	HPAEC-PAD	358:366	HPAEC-PAD	358:366	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	0	11	theme	pressure-assisted	87:103	arg1	extraction					105:114	high hydrostatic pressure-assisted extraction	70:114	high hydrostatic pressure-assisted extraction	70:114	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	7	12	theme	small	1204:1208	arg1	SAXS					1234:1237	SAXS	1234:1237	SAXS	1234:1237	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	12	theme	small	1204:1208	arg1	scattering					1222:1231	synchrotron small angle X-ray scattering	1192:1231	synchrotron small angle X-ray scattering (SAXS)	1192:1238	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	6	13	theme	CaCl2	1061:1065	arg1	solutions					1067:1075	CaCl2 solutions	1061:1075	CaCl2 solutions	1061:1075	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	3	14	theme	alginate	478:485	arg1	yield					487:491	the alginate yield	474:491	the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols	474:617	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	5	15	theme	HPP	874:876	arg1	pre-treatment					878:890	the HPP pre-treatment	870:890	the HPP pre-treatment (SHP)	870:896	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	5	15	theme	HPP	874:876	arg1	SHP					893:895	SHP	893:895	SHP	893:895	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	7	16	dep	strength	1093:1100	arg1	The					1078:1080	The	1078:1080	The	1078:1080	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	0	17	theme	Structural	0:9	arg1	properties					26:35	Structural and functional properties	0:35	Structural and functional properties of alginate	0:47	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	8	18	theme	gel	1356:1358	arg1	strength					1360:1367	the gel strength	1352:1367	the gel strength of SHP	1352:1374	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	1	19	theme	pre-treatment	168:180	arg1	effects					121:127	The effects	117:127	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction	117:207	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	5	20	theme	lower	768:772	arg1	increase					774:781	a lower increase	766:781	a lower increase in alginate extraction yield	766:810	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	5	21	from	increase	774:781	arg1	yield					806:810	alginate extraction yield	786:810	alginate extraction yield	786:810	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	4	22	theme	M	720:720	arg1	sequences					728:736	the M and G sequences	716:736	the M and G sequences	716:736	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	7	23	theme	hydrogel	1127:1134	arg1	beads					1136:1140	the hydrogel beads	1123:1140	the hydrogel beads prepared	1123:1149	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	2	24	theme	technological	406:418	arg1	properties					420:429	functional and technological properties	391:429	functional and technological properties	391:429	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	2	24	theme	technological	406:418	arg1	composition					334:344	composition	334:344	composition	334:344	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	1	25	from	effects	121:127	arg1	extraction					198:207	the alginate extraction	185:207	the alginate extraction	185:207	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	5	26	theme	recalcitrant	838:849	arg1	latissima					854:862	the more recalcitrant S. latissima	829:862	the more recalcitrant S. latissima	829:862	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	1	27	theme	algae	271:275	arg1	species					277:283	two algae species	267:283	two algae species	267:283	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	3	28	from	yield	487:491	arg1	AHP					530:532	AHP	530:532	AHP	530:532	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	3	28	from	yield	487:491	arg1	nodosum					521:527	the less recalcitrant A. nodosum	496:527	the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols	496:617	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	4	29	theme	G	726:726	arg1	sequences					728:736	the M and G sequences	716:736	the M and G sequences	716:736	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	5	30	theme	extract	961:967	arg1	values					937:942	the M/G values	929:942	the M/G values of the resulting extract	929:967	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	1	31	theme	alginate	189:196	arg1	extraction					198:207	the alginate extraction	185:207	the alginate extraction	185:207	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	2	32	theme	functional	391:400	arg1	properties					420:429	functional and technological properties	391:429	functional and technological properties	391:429	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	2	32	theme	functional	391:400	arg1	composition					334:344	composition	334:344	composition	334:344	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	1	33	theme	species	277:283	arg1	nature					257:262	the recalcitrant nature	240:262	the recalcitrant nature of two algae species	240:283	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	5	34	theme	S.	851:852	arg1	latissima					854:862	the more recalcitrant S. latissima	829:862	the more recalcitrant S. latissima	829:862	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	0	35	theme	alginate	40:47	arg1	properties					26:35	Structural and functional properties	0:35	Structural and functional properties of alginate	0:47	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	7	36	theme	X-ray	1216:1220	arg1	SAXS					1234:1237	SAXS	1234:1237	SAXS	1234:1237	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	36	theme	X-ray	1216:1220	arg1	scattering					1222:1231	synchrotron small angle X-ray scattering	1192:1231	synchrotron small angle X-ray scattering (SAXS)	1192:1238	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	3	37	theme	sulphated	567:575	arg1	structures					592:601	sulphated fucoidan/fucan structures	567:601	sulphated fucoidan/fucan structures	567:601	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	6	38	theme	extracts	1009:1016	arg1	properties					982:991	The gelling properties	970:991	The gelling properties of the alginate extracts	970:1016	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	8	39	with	agreement	1380:1388	arg1	conformation					1441:1452	the stiffer rod-like conformation	1420:1452	the stiffer rod-like conformation	1420:1452	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	8	39	with	agreement	1380:1388	arg1	values					1409:1414	the lower M/G values	1395:1414	the lower M/G values	1395:1414	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	8	40	theme	M/G	1405:1407	arg1	values					1409:1414	the lower M/G values	1395:1414	the lower M/G values	1395:1414	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	3	41	theme	fucoidan/fucan	577:590	arg1	structures					592:601	sulphated fucoidan/fucan structures	567:601	sulphated fucoidan/fucan structures	567:601	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	4	42	theme	molecular	633:641	arg1	weight					643:648	the molecular weight	629:648	the molecular weight	629:648	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	4	42	theme	molecular	633:641	arg1	lower					668:672	lower	668:672	lower	668:672	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	7	43	theme	mechanical	1082:1091	arg1	strength					1093:1100	mechanical strength	1082:1100	mechanical strength	1082:1100	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	8	44	theme	HPP	1325:1327	arg1	application					1310:1320	the application	1306:1320	the application of HPP	1306:1327	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	8	45	theme	lower	1399:1403	arg1	values					1409:1414	the lower M/G values	1395:1414	the lower M/G values	1395:1414	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	8	46	theme	rod-like	1432:1439	arg1	conformation					1441:1452	the stiffer rod-like conformation	1420:1452	the stiffer rod-like conformation	1420:1452	Interestingly, the application of HPP significantly improved the gel strength of SHP, in agreement with the lower M/G values and the stiffer rod-like conformation obtained for these samples.					
36876790	2	47	theme	composition	334:344	arg1	terms					325:329	terms	325:329	terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties	325:429	Alginates were deeply characterized in terms of composition, structure (HPAEC-PAD, FTIR, NMR, SEC-MALS), functional and technological properties.					
36876790	5	48	theme	resulting	951:959	arg1	extract					961:967	the resulting extract	947:967	the resulting extract	947:967	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	4	49	theme	M/G	702:704	arg1	ratio					706:710	the M/G ratio	698:710	the M/G ratio	698:710	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	3	50	theme	polyphenols	607:617	arg1	extraction					553:562	the extraction	549:562	the extraction of sulphated fucoidan/fucan structures and polyphenols	549:617	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	4	51	theme	AHP	677:679	arg1	samples					681:687	AHP samples	677:687	AHP samples	677:687	Although the molecular weight was significantly lower in AHP samples, neither the M/G ratio nor the M and G sequences were modified.					
36876790	6	52	theme	gelling	974:980	arg1	properties					982:991	The gelling properties	970:991	The gelling properties of the alginate extracts	970:1016	The gelling properties of the alginate extracts were also explored by external gelation in CaCl2 solutions.					
36876790	5	53	theme	M/G	933:935	arg1	values					937:942	the M/G values	929:942	the M/G values of the resulting extract	929:967	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	5	54	located	observed	816:823	arg2	increase					774:781	a lower increase	766:781	a lower increase in alginate extraction yield	766:810	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	5	54	located	observed	816:823	arg1	contrast					756:763	contrast	756:763	contrast	756:763	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	5	55	theme	alginate	786:793	arg1	yield					806:810	alginate extraction yield	786:810	alginate extraction yield	786:810	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	1	56	theme	high	136:139	arg1	pre-treatment					168:180	the high hydrostatic pressure (HPP) pre-treatment	132:180	the high hydrostatic pressure (HPP) pre-treatment	132:180	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	7	57	theme	cryo-scanning	1245:1257	arg1	Cryo-SEM					1280:1287	Cryo-SEM	1280:1287	Cryo-SEM	1280:1287	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	57	theme	cryo-scanning	1245:1257	arg1	microscopy					1268:1277	cryo-scanning electron microscopy	1245:1277	cryo-scanning electron microscopy (Cryo-SEM)	1245:1288	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	3	58	theme	structures	592:601	arg1	extraction					553:562	the extraction	549:562	the extraction of sulphated fucoidan/fucan structures and polyphenols	549:617	The pre-treatment significantly increased the alginate yield in the less recalcitrant A. nodosum (AHP) also favoring the extraction of sulphated fucoidan/fucan structures and polyphenols.					
36876790	5	59	theme	extraction	795:804	arg1	yield					806:810	alginate extraction yield	786:810	alginate extraction yield	786:810	In contrast, a lower increase in alginate extraction yield was observed for the more recalcitrant S. latissima after the HPP pre-treatment (SHP), but it significantly affected the M/G values of the resulting extract.					
36876790	1	60	theme	hydrostatic	141:151	arg1	pressure					153:160	hydrostatic pressure	141:160	the high hydrostatic pressure (HPP) pre-treatment	132:180	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	1	60	theme	hydrostatic	141:151	arg1	HPP					163:165	HPP	163:165	HPP	163:165	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	7	61	theme	electron	1259:1266	arg1	Cryo-SEM					1280:1287	Cryo-SEM	1280:1287	Cryo-SEM	1280:1287	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	61	theme	electron	1259:1266	arg1	microscopy					1268:1277	cryo-scanning electron microscopy	1245:1277	cryo-scanning electron microscopy (Cryo-SEM)	1245:1288	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	62	theme	synchrotron	1192:1202	arg1	SAXS					1234:1237	SAXS	1234:1237	SAXS	1234:1237	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	62	theme	synchrotron	1192:1202	arg1	scattering					1222:1231	synchrotron small angle X-ray scattering	1192:1231	synchrotron small angle X-ray scattering (SAXS)	1192:1238	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	0	63	theme	functional	15:24	arg1	properties					26:35	Structural and functional properties	0:35	Structural and functional properties of alginate	0:47	Structural and functional properties of alginate obtained by means of high hydrostatic pressure-assisted extraction.					
36876790	1	64	theme	pressure	153:160	arg1	pre-treatment					168:180	the high hydrostatic pressure (HPP) pre-treatment	132:180	the high hydrostatic pressure (HPP) pre-treatment	132:180	The effects of the high hydrostatic pressure (HPP) pre-treatment on the alginate extraction were seen to greatly depend on the recalcitrant nature of two algae species.					
36876790	7	65	theme	beads	1136:1140	arg1	nanostructure					1106:1118	nanostructure	1106:1118	nanostructure	1106:1118	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36876790	7	65	theme	beads	1136:1140	arg1	strength					1093:1100	mechanical strength	1082:1100	mechanical strength	1082:1100	The mechanical strength and nanostructure of the hydrogel beads prepared were determined using compression tests, synchrotron small angle X-ray scattering (SAXS), and cryo-scanning electron microscopy (Cryo-SEM).					
36151499	1	0	theme	leaflet	156:162	arg1	components					129:138	the main components	120:138	the main components of the external leaflet of the outer membrane of Gram-negative bacteria	120:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	1	0	theme	leaflet	156:162	arg1	Lipopolysaccharides					89:107	Lipopolysaccharides	89:107	Lipopolysaccharides (LPSs)	89:114	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	4	1	theme	adjuvants	908:916	arg1	vaccines					941:948	vaccines	941:948	vaccines	941:948	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	4	1	theme	adjuvants	908:916	arg1	quality					897:903	the quality	893:903	the quality of adjuvants and/or medications	893:935	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	3	2	from	information	602:612	arg1	motifs					621:626	the motifs	617:626	the motifs	617:626	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	4	3	theme	structural	976:985	arg1	study					987:991	structural study of LPSs is complex, and it can be achieved with the right combination of different techniques	976:1085	structural study of LPSs is complex, and it can be achieved with the right combination of different techniques	976:1085	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	2	4	with	interaction	322:332	arg1	environment					367:377	the external environment	354:377	the external environment	354:377	They exert multiple functions, starting from conferring stability to the bacterial membrane to mediating the interaction of the microbe with the external environment.					
36151499	2	5	theme	bacterial	286:294	arg1	membrane					296:303	the bacterial membrane	282:303	the bacterial membrane to mediating the interaction of the microbe with the external environment	282:377	They exert multiple functions, starting from conferring stability to the bacterial membrane to mediating the interaction of the microbe with the external environment.					
36151499	3	6	theme	structure	539:547	arg1	determination					518:530	the determination	514:530	the determination of the structure of these molecules	514:566	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	3	6	theme	structure	539:547	arg1	crucial					571:577	crucial	571:577	crucial	571:577	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	5	7	theme	matrix-assisted	1213:1227	arg1	MALDI					1258:1262	MALDI	1258:1262	MALDI	1258:1262	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	5	7	theme	matrix-assisted	1213:1227	arg1	desorption/ionization					1235:1255	the matrix-assisted laser desorption/ionization	1209:1255	the matrix-assisted laser desorption/ionization (MALDI)	1209:1263	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	3	8	theme	same	479:482	arg1	species					484:490	the same species	475:490	the same species	475:490	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	1	9	theme	membrane	177:184	arg1	leaflet					156:162	the external leaflet	143:162	the external leaflet of the outer membrane of Gram-negative bacteria	143:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	1	10	theme	outer	171:175	arg1	membrane					177:184	the outer membrane	167:184	the outer membrane of Gram-negative bacteria	167:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	0	11	theme	Lipopolysaccharide	11:28	arg1	Composition					30:40	Lipopolysaccharide Composition	11:40	Lipopolysaccharide Composition	11:40	Dissecting Lipopolysaccharide Composition and Structure by GC-MS and MALDI Spectrometry.					
36151499	3	12	theme	commensal	709:717	arg1	bacterium					692:700	a bacterium	690:700	a bacterium of the commensal or beneficial microbiota	690:742	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	3	13	theme	molecules	558:566	arg1	structure					539:547	the structure	535:547	the structure of these molecules	535:566	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	3	14	theme	tremendous	430:439	arg1	diversity					441:449	tremendous diversity	430:449	tremendous diversity even within bacteria of the same species	430:490	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	3	15	theme	beneficial	722:731	arg1	microbiota					733:742	beneficial microbiota	722:742	beneficial microbiota	722:742	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	1	16	theme	Gram-negative	189:201	arg1	bacteria					203:210	Gram-negative bacteria	189:210	Gram-negative bacteria	189:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	1	17	theme	bacteria	203:210	arg1	membrane					177:184	the outer membrane	167:184	the outer membrane of Gram-negative bacteria	167:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	3	18	theme	LPSs	417:420	arg1	composition					384:394	The composition	380:394	The composition	380:394	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	3	18	theme	LPSs	417:420	arg1	structure					404:412	the structure	400:412	the structure of LPSs	400:420	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	2	19	theme	microbe	341:347	arg1	interaction					322:332	the interaction	318:332	the interaction of the microbe with the external environment	318:377	They exert multiple functions, starting from conferring stability to the bacterial membrane to mediating the interaction of the microbe with the external environment.					
36151499	4	20	theme	medications	925:935	arg1	vaccines					941:948	vaccines	941:948	vaccines	941:948	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	4	20	theme	medications	925:935	arg1	quality					897:903	the quality	893:903	the quality of adjuvants and/or medications	893:935	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	3	21	theme	key	628:630	arg1	information					602:612	information	602:612	information on the motifs key for the virulence of a pathogen	602:662	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	2	22	theme	multiple	224:231	arg1	functions					233:241	multiple functions	224:241	multiple functions	224:241	They exert multiple functions, starting from conferring stability to the bacterial membrane to mediating the interaction of the microbe with the external environment.					
36151499	4	23	theme	techniques	1076:1085	arg1	combination					1051:1061	the right combination	1041:1061	the right combination of different techniques	1041:1085	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	5	24	theme	MS-based	1135:1142	arg1	approaches					1144:1153	the two MS-based approaches	1127:1153	the two MS-based approaches	1127:1153	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	3	25	theme	microbiota	733:742	arg1	bacterium					692:700	a bacterium	690:700	a bacterium of the commensal or beneficial microbiota	690:742	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	4	26	theme	antibiotic	843:852	arg1	use					833:835	the use	829:835	the use of an antibiotic	829:852	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	1	27	theme	main	124:127	arg1	components					129:138	the main components	120:138	the main components of the external leaflet of the outer membrane of Gram-negative bacteria	120:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	1	27	theme	main	124:127	arg1	Lipopolysaccharides					89:107	Lipopolysaccharides	89:107	Lipopolysaccharides (LPSs)	89:114	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	5	28	theme	gas	1160:1162	arg1	GC-MS					1198:1202	GC-MS	1198:1202	GC-MS	1198:1202	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	5	28	theme	gas	1160:1162	arg1	spectrometry					1184:1195	the gas chromatography-mass spectrometry	1156:1195	the gas chromatography-mass spectrometry (GC-MS)	1156:1203	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	3	29	theme	pathogen	655:662	arg1	virulence					640:648	the virulence	636:648	the virulence of a pathogen	636:662	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	4	30	theme	structural	758:767	arg1	data					769:772	structural data	758:772	structural data	758:772	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	3	31	theme	species	484:490	arg1	diversity					441:449	tremendous diversity	430:449	tremendous diversity even within bacteria of the same species	430:490	The composition and the structure of LPSs present tremendous diversity even within bacteria of the same species, and for this reason, the determination of the structure of these molecules is crucial because it can provide information on the motifs key for the virulence of a pathogen or that are associated to a bacterium of the commensal or beneficial microbiota.					
36151499	5	32	theme	chromatography-mass	1164:1182	arg1	GC-MS					1198:1202	GC-MS	1198:1202	GC-MS	1198:1202	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	5	32	theme	chromatography-mass	1164:1182	arg1	spectrometry					1184:1195	the gas chromatography-mass spectrometry	1156:1195	the gas chromatography-mass spectrometry (GC-MS)	1156:1203	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	4	33	used	used	870:873	arg2	tools					878:882	tools	878:882	tools	878:882	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	4	33	used	used	870:873	arg2	they					858:861	they	858:861	they	858:861	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	4	34	theme	right	1045:1049	arg1	combination					1051:1061	the right combination	1041:1061	the right combination of different techniques	1041:1085	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	2	35	theme	external	358:365	arg1	environment					367:377	the external environment	354:377	the external environment	354:377	They exert multiple functions, starting from conferring stability to the bacterial membrane to mediating the interaction of the microbe with the external environment.					
36151499	0	36	theme	MALDI	69:73	arg1	Spectrometry					75:86	MALDI Spectrometry	69:86	MALDI Spectrometry	69:86	Dissecting Lipopolysaccharide Composition and Structure by GC-MS and MALDI Spectrometry.					
36151499	5	37	theme	laser	1229:1233	arg1	MALDI					1258:1262	MALDI	1258:1262	MALDI	1258:1262	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	5	37	theme	laser	1229:1233	arg1	desorption/ionization					1235:1255	the matrix-assisted laser desorption/ionization	1209:1255	the matrix-assisted laser desorption/ionization (MALDI)	1209:1263	In this frame, this chapter focuses on the two MS-based approaches, the gas chromatography-mass spectrometry (GC-MS) and the matrix-assisted laser desorption/ionization (MALDI).					
36151499	4	38	theme	different	1066:1074	arg1	techniques					1076:1085	different techniques	1066:1085	different techniques	1066:1085	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
36151499	1	39	theme	external	147:154	arg1	leaflet					156:162	the external leaflet	143:162	the external leaflet of the outer membrane of Gram-negative bacteria	143:210	Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria.					
36151499	4	40	theme	LPS.The	968:974	arg1	use					961:963	use	961:963	use of LPS.The	961:974	In addition, structural data disclose the effects triggered from a mutation or from the use of an antibiotic, or they can be used as tools to check the quality of adjuvants and/or medications, as vaccines, that make use of LPS.The structural study of LPSs is complex, and it can be achieved with the right combination of different techniques.					
35843394	3	0	theme	facile	505:510	arg1	system					532:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	1	1	theme	lignocellulose	241:254	arg1	hydrogels					256:264	lignocellulose hydrogels	241:264	lignocellulose hydrogels (LHs)	241:270	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	1	1	theme	lignocellulose	241:254	arg1	LHs					267:269	LHs	267:269	LHs	267:269	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	6	2	theme	zinc-ion	825:832	arg1	supercapacitor					841:854	a zinc-ion hybrid supercapacitor	823:854	a zinc-ion hybrid supercapacitor	823:854	Inspired by its superior ionic conductivity, the hydrogels were assembled into a solid-state electrolyte for a zinc-ion hybrid supercapacitor.					
35843394	3	3	theme	ZnCl2/CaCl2	512:522	arg1	system					532:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	2	4	theme	alkaline	344:351	arg1	peroxide					353:360	alkaline peroxide	344:360	alkaline peroxide	344:360	Herein, corncob residues from furfural production were pretreated with alkaline peroxide to regulate the lignin content.					
35843394	2	5	from	production	312:321	arg1	residues					289:296	corncob residues	281:296	corncob residues from furfural production	281:321	Herein, corncob residues from furfural production were pretreated with alkaline peroxide to regulate the lignin content.					
35843394	7	6	theme	simple	892:897	arg1	route					913:917	a feasible, simple, and low-cost route	880:917	a feasible, simple, and low-cost route for lignin-containing hydrogel preparation	880:960	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	5	7	contain	containing	642:651	arg1	material					633:640	Substrate material	623:640	Substrate material containing 10.75% lignin	623:665	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	5	7	contain	containing	642:651	arg2	lignin					660:665	10.75% lignin	653:665	10.75% lignin	653:665	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	5	8	theme	best	677:680	arg1	76.71 kPa					702:710	76.71 kPa	702:710	76.71 kPa	702:710	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	5	8	theme	best	677:680	arg1	stress					694:699	the best compressive stress	673:699	the best compressive stress (76.71 kPa)	673:711	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	4	9	theme	flexible	595:602	arg1	LHs					604:606	flexible LHs	595:606	flexible LHs	595:606	The inorganic salt solvents were served as linkers and flexible LHs were obtained.					
35843394	5	10	theme	Substrate	623:631	arg1	material					633:640	Substrate material	623:640	Substrate material containing 10.75% lignin	623:665	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	3	11	with	composites	415:424	arg1	content					446:452	various lignin content	431:452	various lignin content	431:452	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	3	12	theme	various	431:437	arg1	content					446:452	various lignin content	431:452	various lignin content	431:452	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	6	13	theme	solid-state	795:805	arg1	electrolyte					807:817	a solid-state electrolyte	793:817	a solid-state electrolyte for a zinc-ion hybrid supercapacitor	793:854	Inspired by its superior ionic conductivity, the hydrogels were assembled into a solid-state electrolyte for a zinc-ion hybrid supercapacitor.					
35843394	5	14	theme	10.75	653:657	arg1	%					658:658	%	658:658	%	658:658	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	2	15	theme	furfural	303:310	arg1	production					312:321	furfural production	303:321	furfural production	303:321	Herein, corncob residues from furfural production were pretreated with alkaline peroxide to regulate the lignin content.					
35843394	2	16	theme	lignin	378:383	arg1	content					385:391	the lignin content	374:391	the lignin content	374:391	Herein, corncob residues from furfural production were pretreated with alkaline peroxide to regulate the lignin content.					
35843394	5	17	theme	%	658:658	arg1	lignin					660:665	10.75% lignin	653:665	10.75% lignin	653:665	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	7	18	theme	hydrogel	941:948	arg1	preparation					950:960	lignin-containing hydrogel preparation	923:960	lignin-containing hydrogel preparation	923:960	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	3	19	theme	lignin	439:444	arg1	content					446:452	various lignin content	431:452	various lignin content	431:452	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	1	20	dep	cellulose	187:195	arg1	the					183:185	the	183:185	the	183:185	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	7	21	theme	lignocellulosic	1033:1047	arg1	wastes					1049:1054	agro-industrial lignocellulosic wastes	1017:1054	agro-industrial lignocellulosic wastes	1017:1054	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	7	22	theme	wastes	1049:1054	arg1	application					1002:1012	the high-value application	987:1012	the high-value application of agro-industrial lignocellulosic wastes	987:1054	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	2	23	theme	corncob	281:287	arg1	residues					289:296	corncob residues	281:296	corncob residues from furfural production	281:321	Herein, corncob residues from furfural production were pretreated with alkaline peroxide to regulate the lignin content.					
35843394	1	24	theme	effective	125:133	arg1	system					143:148	an effective solvent system	122:148	an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs)	122:270	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	7	25	theme	feasible	882:889	arg1	route					913:917	a feasible, simple, and low-cost route	880:917	a feasible, simple, and low-cost route for lignin-containing hydrogel preparation	880:960	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	0	26	theme	corncob	41:47	arg1	residues					49:56	corncob residues	41:56	corncob residues	41:56	Lignocellulose hydrogels fabricated from corncob residues through a green solvent system.					
35843394	1	27	from	lignin	201:206	arg1	residues					219:226	biomass residues	211:226	biomass residues	211:226	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	5	28	theme	compressive	682:692	arg1	76.71 kPa					702:710	76.71 kPa	702:710	76.71 kPa	702:710	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	5	28	theme	compressive	682:692	arg1	stress					694:699	the best compressive stress	673:699	the best compressive stress (76.71 kPa)	673:711	Substrate material containing 10.75% lignin shows the best compressive stress (76.71 kPa).					
35843394	3	29	theme	green	495:499	arg1	system					532:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	3	30	theme	lignin/cellulose	398:413	arg1	composites					415:424	The lignin/cellulose composites	394:424	The lignin/cellulose composites with various lignin content	394:452	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	4	31	theme	salt	554:557	arg1	solvents					559:566	The inorganic salt solvents	540:566	The inorganic salt solvents	540:566	The inorganic salt solvents were served as linkers and flexible LHs were obtained.					
35843394	1	32	from	cellulose	187:195	arg1	residues					219:226	biomass residues	211:226	biomass residues	211:226	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	4	33	theme	inorganic	544:552	arg1	solvents					559:566	The inorganic salt solvents	540:566	The inorganic salt solvents	540:566	The inorganic salt solvents were served as linkers and flexible LHs were obtained.					
35843394	7	34	theme	high-value	991:1000	arg1	application					1002:1012	the high-value application	987:1012	the high-value application of agro-industrial lignocellulosic wastes	987:1054	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	7	35	theme	lignin-containing	923:939	arg1	preparation					950:960	lignin-containing hydrogel preparation	923:960	lignin-containing hydrogel preparation	923:960	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	1	36	theme	biomass	211:217	arg1	residues					219:226	biomass residues	211:226	biomass residues	211:226	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35843394	7	37	theme	agro-industrial	1017:1031	arg1	wastes					1049:1054	agro-industrial lignocellulosic wastes	1017:1054	agro-industrial lignocellulosic wastes	1017:1054	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	7	38	theme	low-cost	904:911	arg1	route					913:917	a feasible, simple, and low-cost route	880:917	a feasible, simple, and low-cost route for lignin-containing hydrogel preparation	880:960	This research develops a feasible, simple, and low-cost route for lignin-containing hydrogel preparation and offers insights into the high-value application of agro-industrial lignocellulosic wastes.					
35843394	0	39	theme	solvent	74:80	arg1	system					82:87	a green solvent system	66:87	a green solvent system	66:87	Lignocellulose hydrogels fabricated from corncob residues through a green solvent system.					
35843394	6	40	theme	hybrid	834:839	arg1	supercapacitor					841:854	a zinc-ion hybrid supercapacitor	823:854	a zinc-ion hybrid supercapacitor	823:854	Inspired by its superior ionic conductivity, the hydrogels were assembled into a solid-state electrolyte for a zinc-ion hybrid supercapacitor.					
35843394	0	41	dep	hydrogels	15:23	arg1	fabricated					25:34	fabricated	25:34	hydrogels fabricated from corncob residues through a green solvent system	15:87	Lignocellulose hydrogels fabricated from corncob residues through a green solvent system.					
35843394	6	42	theme	ionic	739:743	arg1	conductivity					745:756	its superior ionic conductivity	726:756	its superior ionic conductivity	726:756	Inspired by its superior ionic conductivity, the hydrogels were assembled into a solid-state electrolyte for a zinc-ion hybrid supercapacitor.					
35843394	3	43	theme	solvent	524:530	arg1	system					532:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	a green and facile ZnCl2/CaCl2 solvent system	493:537	The lignin/cellulose composites with various lignin content were then dissolved and regenerated by a green and facile ZnCl2/CaCl2 solvent system.					
35843394	0	44	theme	green	68:72	arg1	system					82:87	a green solvent system	66:87	a green solvent system	66:87	Lignocellulose hydrogels fabricated from corncob residues through a green solvent system.					
35843394	6	45	theme	superior	730:737	arg1	conductivity					745:756	its superior ionic conductivity	726:756	its superior ionic conductivity	726:756	Inspired by its superior ionic conductivity, the hydrogels were assembled into a solid-state electrolyte for a zinc-ion hybrid supercapacitor.					
35843394	1	46	theme	solvent	135:141	arg1	system					143:148	an effective solvent system	122:148	an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs)	122:270	It is still a challenge to find an effective solvent system that can simultaneously dissolve the cellulose and lignin in biomass residues to fabricate lignocellulose hydrogels (LHs).					
35489622	6	0	theme	GFF	789:791	arg1	diameter					728:735	diameter	728:735	diameter	728:735	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	6	0	theme	GFF	789:791	arg1	parameters					752:761	mechanical parameters	741:761	mechanical parameters	741:761	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	7	1	theme	material	845:852	arg1	removal					824:830	the removal	820:830	the removal of amorphous material from the fiber post-treatment	820:882	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	9	2	theme	raw	1159:1161	arg1	GFF					1193:1195	raw and alkali treated cellulosic GFF	1159:1195	GFF	1193:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	7	3	dep	68.43 nm	1001:1008	arg1	to					998:999	to	998:999	to	998:999	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	5	4	theme	improved	624:631	arg1	strength					641:648	improved tensile strength	624:648	improved tensile strength	624:648	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	9	5	theme	treated	1174:1180	arg1	GFF					1193:1195	raw and alkali treated cellulosic GFF	1159:1195	GFF	1193:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	9	6	theme	GFF	1193:1195	arg1	analysis					1147:1154	Morphological analysis	1133:1154	Morphological analysis of raw and alkali treated cellulosic GFF	1133:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	1	7	theme	treated	179:185	arg1	Flavescens					205:214	alkali treated cellulosic Grewia Flavescens	172:214	alkali treated cellulosic Grewia Flavescens	172:214	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	7	8	from	%	965:965	arg1	size					979:982	crystal size	971:982	crystal size	971:982	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	8	from	%	965:965	arg1	improvement					910:920	improvement	910:920	improvement in crystallinity index from 16.01% to 26.72%	910:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	8	from	%	965:965	arg1	index					939:943	crystallinity index	925:943	crystallinity index from 16.01% to 26.72%	925:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	5	9	theme	fiber	601:605	arg1	test					615:618	single fiber tensile test	594:618	single fiber tensile test	594:618	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	9	10	theme	enhanced	1203:1210	arg1	surface					1218:1224	enhanced rough surface	1203:1224	enhanced rough surface of fiber after alkalization	1203:1252	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	2	11	theme	fiber	320:324	arg1	constituents					286:297	the chemical constituents	273:297	the chemical constituents of Grewia Flavescens fiber (GFF)	273:330	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	1	12	theme	Grewia	198:203	arg1	Flavescens					205:214	alkali treated cellulosic Grewia Flavescens	172:214	alkali treated cellulosic Grewia Flavescens	172:214	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	2	13	theme	Grewia	302:307	arg1	GFF					327:329	GFF	327:329	GFF	327:329	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	2	13	theme	Grewia	302:307	arg1	fiber					320:324	Grewia Flavescens fiber	302:324	Grewia Flavescens fiber (GFF)	302:330	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	9	14	theme	fiber	1229:1233	arg1	surface					1218:1224	enhanced rough surface	1203:1224	enhanced rough surface of fiber after alkalization	1203:1252	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	7	15	theme	crystal	971:977	arg1	size					979:982	crystal size	971:982	crystal size	971:982	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	9	16	theme	alkali	1167:1172	arg1	GFF					1193:1195	raw and alkali treated cellulosic GFF	1159:1195	GFF	1193:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	7	17	dep	%	955:955	arg1	to					957:958	to	957:958	to	957:958	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	0	18	theme	Flavescens	61:70	arg1	fiber					80:84	cellulosic Grewia Flavescens natural fiber	43:84	cellulosic Grewia Flavescens natural fiber	43:84	Characterization of raw and alkali treated cellulosic Grewia Flavescens natural fiber.					
35489622	2	19	theme	standard	250:257	arg1	methods					264:270	standard test methods	250:270	standard test methods	250:270	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	1	20	theme	morphological	139:151	arg1	characteristics					153:167	The physicochemical, mechanical, thermal as well as morphological characteristics	87:167	characteristics	153:167	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	10	21	theme	bio	1434:1436	arg1	composites					1438:1447	bio composites	1434:1447	bio composites	1434:1447	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35489622	7	22	theme	16.01	950:954	arg1	%					955:955	%	955:955	%	955:955	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	9	23	theme	particles	1303:1311	arg1	elimination					1265:1275	elimination	1265:1275	elimination of impurities and foreign particles from the fiber surface	1265:1334	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	5	24	theme	GFF	572:574	arg1	properties					558:567	Mechanical properties	547:567	Mechanical properties of GFF	547:574	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	4	25	theme	optimal	457:463	arg1	alkalization					465:476	optimal alkalization	457:476	optimal alkalization	457:476	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	7	26	from	post-treatment	869:882	arg1	removal					824:830	the removal	820:830	the removal of amorphous material from the fiber post-treatment	820:882	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	3	27	theme	soaking	389:395	arg1	time					397:400	45 min soaking time	382:400	45 min soaking time	382:400	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	1	28	theme	physicochemical	91:105	arg1	characteristics					153:167	The physicochemical, mechanical, thermal as well as morphological characteristics	87:167	characteristics	153:167	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	3	29	theme	5	364:364	arg1	%					365:365	%	365:365	%	365:365	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	3	30	theme	surface-modified	427:442	arg1	Fiber					347:351	Fiber	347:351	Fiber treated in 5% (w/v) NaOH for 45 min soaking time	347:400	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	3	30	theme	surface-modified	427:442	arg1	fiber					444:448	optimally surface-modified fiber	417:448	optimally surface-modified fiber	417:448	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	0	31	theme	raw	20:22	arg1	Characterization					0:15	Characterization	0:15	Characterization of raw and alkali	0:33	Characterization of raw and alkali treated cellulosic Grewia Flavescens natural fiber.					
35489622	8	32	theme	thermal	1052:1058	arg1	temperature					1072:1082	thermal degradation temperature	1052:1082	thermal degradation temperature	1052:1082	Thermal stability and thermal degradation temperature are found to be improved after alkali treatment.					
35489622	1	33	theme	mechanical	108:117	arg1	characteristics					153:167	The physicochemical, mechanical, thermal as well as morphological characteristics	87:167	characteristics	153:167	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	0	34	theme	alkali	28:33	arg1	Characterization					0:15	Characterization	0:15	Characterization of raw and alkali	0:33	Characterization of raw and alkali treated cellulosic Grewia Flavescens natural fiber.					
35489622	4	35	from	enhancement	491:501	arg1	%					544:544	58.46% to 68.31%	529:544	58.46% to 68.31%	529:544	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	4	36	theme	cellulose	506:514	arg1	content					516:522	cellulose content	506:522	cellulose content from 58.46% to 68.31%	506:544	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	10	37	theme	studied	1347:1353	arg1	good					1373:1376	good	1373:1376	good	1373:1376	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35489622	10	37	theme	studied	1347:1353	arg1	GFF					1355:1357	Presently studied GFF	1337:1357	Presently studied GFF	1337:1357	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35489622	7	38	from	68.43 nm	1001:1008	arg1	size					979:982	crystal size	971:982	crystal size	971:982	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	38	from	68.43 nm	1001:1008	arg1	improvement					910:920	improvement	910:920	improvement in crystallinity index from 16.01% to 26.72%	910:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	5	39	theme	tensile	607:613	arg1	test					615:618	single fiber tensile test	594:618	single fiber tensile test	594:618	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	6	40	theme	statistical	690:700	arg1	analysis					702:709	Weibull statistical analysis	682:709	Weibull statistical analysis	682:709	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	7	41	theme	fiber	863:867	arg1	post-treatment					869:882	the fiber post-treatment	859:882	the fiber post-treatment	859:882	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	4	42	theme	68.31	539:543	arg1	%					534:534	%	534:534	%	534:534	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	10	43	theme	man-made	1404:1411	arg1	fibers					1413:1418	the harmful man-made fibers	1392:1418	the harmful man-made fibers	1392:1418	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35489622	6	44	theme	treated	781:787	arg1	GFF					789:791	raw as well as treated GFF	766:791	raw as well as treated GFF	766:791	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	9	45	theme	cellulosic	1182:1191	arg1	GFF					1193:1195	raw and alkali treated cellulosic GFF	1159:1195	GFF	1193:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	2	46	theme	chemical	277:284	arg1	constituents					286:297	the chemical constituents	273:297	the chemical constituents of Grewia Flavescens fiber (GFF)	273:330	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	7	47	theme	amorphous	835:843	arg1	material					845:852	amorphous material	835:852	amorphous material	835:852	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	1	48	theme	alkali	172:177	arg1	Flavescens					205:214	alkali treated cellulosic Grewia Flavescens	172:214	alkali treated cellulosic Grewia Flavescens	172:214	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	0	49	theme	cellulosic	43:52	arg1	fiber					80:84	cellulosic Grewia Flavescens natural fiber	43:84	cellulosic Grewia Flavescens natural fiber	43:84	Characterization of raw and alkali treated cellulosic Grewia Flavescens natural fiber.					
35489622	5	50	theme	single	594:599	arg1	test					615:618	single fiber tensile test	594:618	single fiber tensile test	594:618	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	6	51	theme	raw	766:768	arg1	GFF					789:791	raw as well as treated GFF	766:791	raw as well as treated GFF	766:791	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	1	52	theme	cellulosic	187:196	arg1	Flavescens					205:214	alkali treated cellulosic Grewia Flavescens	172:214	alkali treated cellulosic Grewia Flavescens	172:214	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	10	53	theme	harmful	1396:1402	arg1	fibers					1413:1418	the harmful man-made fibers	1392:1418	the harmful man-made fibers	1392:1418	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35489622	9	54	theme	rough	1212:1216	arg1	surface					1218:1224	enhanced rough surface	1203:1224	enhanced rough surface of fiber after alkalization	1203:1252	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	2	55	theme	Flavescens	309:318	arg1	GFF					327:329	GFF	327:329	GFF	327:329	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	2	55	theme	Flavescens	309:318	arg1	fiber					320:324	Grewia Flavescens fiber	302:324	Grewia Flavescens fiber (GFF)	302:330	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	1	56	theme	Flavescens	205:214	arg1	characteristics					153:167	The physicochemical, mechanical, thermal as well as morphological characteristics	87:167	characteristics	153:167	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	7	57	from	size	979:982	arg1	%					965:965	16.01% to 26.72%	950:965	16.01% to 26.72%	950:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	57	from	size	979:982	arg1	index					939:943	crystallinity index	925:943	crystallinity index from 16.01% to 26.72%	925:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	58	theme	FTIR	794:797	arg1	spectroscopy					799:810	FTIR spectroscopy	794:810	FTIR spectroscopy	794:810	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	5	59	theme	tensile	633:639	arg1	strength					641:648	improved tensile strength	624:648	improved tensile strength	624:648	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	7	60	from	improvement	910:920	arg1	%					965:965	16.01% to 26.72%	950:965	16.01% to 26.72%	950:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	7	60	from	improvement	910:920	arg1	index					939:943	crystallinity index	925:943	crystallinity index from 16.01% to 26.72%	925:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	0	61	theme	natural	72:78	arg1	fiber					80:84	cellulosic Grewia Flavescens natural fiber	43:84	cellulosic Grewia Flavescens natural fiber	43:84	Characterization of raw and alkali treated cellulosic Grewia Flavescens natural fiber.					
35489622	2	62	theme	test	259:262	arg1	methods					264:270	standard test methods	250:270	standard test methods	250:270	Using standard test methods, the chemical constituents of Grewia Flavescens fiber (GFF) are evaluated.					
35489622	1	63	dep	mechanical	108:117	arg1	thermal					120:126	thermal	120:126	thermal	120:126	The physicochemical, mechanical, thermal as well as morphological characteristics of alkali treated cellulosic Grewia Flavescens are reported in this paper.					
35489622	9	64	theme	impurities	1280:1289	arg1	elimination					1265:1275	elimination	1265:1275	elimination of impurities and foreign particles from the fiber surface	1265:1334	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	7	65	theme	26.72	960:964	arg1	%					955:955	%	955:955	%	955:955	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	3	66	dep	%	365:365	arg1	w/v					368:370	w/v	368:370	w/v	368:370	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	9	67	theme	foreign	1295:1301	arg1	particles					1303:1311	foreign particles	1295:1311	foreign particles	1295:1311	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	6	68	theme	Weibull	682:688	arg1	analysis					702:709	Weibull statistical analysis	682:709	Weibull statistical analysis	682:709	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	4	69	from	%	544:544	arg1	enhancement					491:501	an enhancement	488:501	an enhancement of cellulose content from 58.46% to 68.31%	488:544	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	4	69	from	%	544:544	arg1	content					516:522	cellulose content	506:522	cellulose content from 58.46% to 68.31%	506:544	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	4	70	dep	%	534:534	arg1	to					536:537	to	536:537	to	536:537	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	8	71	theme	Thermal	1030:1036	arg1	stability					1038:1046	Thermal stability	1030:1046	Thermal stability	1030:1046	Thermal stability and thermal degradation temperature are found to be improved after alkali treatment.					
35489622	9	72	theme	fiber	1322:1326	arg1	surface					1328:1334	the fiber surface	1318:1334	the fiber surface	1318:1334	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	9	73	from	surface	1328:1334	arg1	elimination					1265:1275	elimination	1265:1275	elimination of impurities and foreign particles from the fiber surface	1265:1334	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	7	74	theme	crystallinity	925:937	arg1	index					939:943	crystallinity index	925:943	crystallinity index from 16.01% to 26.72%	925:965	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	4	75	theme	58.46	529:533	arg1	%					534:534	%	534:534	%	534:534	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	8	76	theme	degradation	1060:1070	arg1	temperature					1072:1082	thermal degradation temperature	1052:1082	thermal degradation temperature	1052:1082	Thermal stability and thermal degradation temperature are found to be improved after alkali treatment.					
35489622	5	77	theme	Mechanical	547:556	arg1	properties					558:567	Mechanical properties	547:567	Mechanical properties of GFF	547:574	Mechanical properties of GFF are determined by single fiber tensile test and improved tensile strength is achieved after alkalization.					
35489622	3	78	theme	%	365:365	arg1	NaOH					373:376	5% (w/v) NaOH	364:376	5% (w/v) NaOH	364:376	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	3	79	theme	45 min	382:387	arg1	time					397:400	45 min soaking time	382:400	45 min soaking time	382:400	Fiber treated in 5% (w/v) NaOH for 45 min soaking time is regarded as optimally surface-modified fiber.					
35489622	6	80	theme	mechanical	741:750	arg1	parameters					752:761	mechanical parameters	741:761	mechanical parameters	741:761	Weibull statistical analysis is performed for diameter and mechanical parameters of raw as well as treated GFF.					
35489622	4	81	theme	content	516:522	arg1	enhancement					491:501	an enhancement	488:501	an enhancement of cellulose content from 58.46% to 68.31%	488:544	After optimal alkalization, there is an enhancement of cellulose content from 58.46% to 68.31%.					
35489622	7	82	theme	XRD	888:890	arg1	analysis					892:899	XRD analysis	888:899	XRD analysis	888:899	FTIR spectroscopy reveals the removal of amorphous material from the fiber post-treatment and XRD analysis confirms improvement in crystallinity index from 16.01% to 26.72% and crystal size from 62.90 nm to 68.43 nm after alkalization.					
35489622	9	83	theme	Morphological	1133:1145	arg1	analysis					1147:1154	Morphological analysis	1133:1154	Morphological analysis of raw and alkali treated cellulosic GFF	1133:1195	Morphological analysis of raw and alkali treated cellulosic GFF shows enhanced rough surface of fiber after alkalization because of elimination of impurities and foreign particles from the fiber surface.					
35489622	8	84	theme	alkali	1115:1120	arg1	treatment					1122:1130	alkali treatment	1115:1130	alkali treatment	1115:1130	Thermal stability and thermal degradation temperature are found to be improved after alkali treatment.					
35489622	10	85	dep	good	1373:1376	arg1	substitute					1378:1387	substitute	1378:1387	substitute to the harmful man-made fibers for making of bio composites	1378:1447	Presently studied GFF seems to be a good substitute to the harmful man-made fibers for making of bio composites.					
35622257	4	0	from	decrease	900:907	arg1	concentration					916:928	the concentration	912:928	the concentration of oxyproline and glycosaminoglycans	912:965	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	1	theme	pronounced	889:898	arg1	decrease					900:907	more pronounced decrease	884:907	more pronounced decrease in the concentration of oxyproline and glycosaminoglycans	884:965	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	3	2	theme	experimental	732:743	arg1	periodontitis					745:757	experimental periodontitis	732:757	experimental periodontitis	732:757	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	3	from	tissue	698:703	arg1	content					629:635	the content	625:635	the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	625:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	1	4	theme	periodontal	150:160	arg1	tissue					162:167	the periodontal tissue	146:167	the periodontal tissue	146:167	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	0	5	theme	Chronic	92:98	arg1	Syndrome					105:112	Chronic Pain Syndrome	92:112	Chronic Pain Syndrome	92:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	0	6	from	Disorders	0:8	arg1	Rats					64:67	Rats	64:67	Rats with Periodontitis and Chronic Pain Syndrome	64:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	1	7	from	composition	131:141	arg1	rats					172:175	rats	172:175	rats with experimental periodontitis and chronic pain syndrome	172:233	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	3	8	with	animals	719:725	arg1	periodontitis					745:757	experimental periodontitis	732:757	experimental periodontitis	732:757	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	9	theme	malondialdehyde	1018:1032	arg1	content					984:990	the content	980:990	the content of acylhydroperoxides and malondialdehyde	980:1032	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	3	10	from	malondialdehyde	640:654	arg1	tissue					698:703	the periodontal tissue	682:703	the periodontal tissue	682:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	0	11	with	Rats	64:67	arg1	Periodontitis					74:86	Periodontitis	74:86	Periodontitis	74:86	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	0	11	with	Rats	64:67	arg1	Syndrome					105:112	Chronic Pain Syndrome	92:112	Chronic Pain Syndrome	92:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	3	12	theme	oxyproline	552:561	arg1	concentration					535:547	the concentration	531:547	the concentration of oxyproline, glycosaminoglycans, and catalase activity	531:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	13	from	increase	613:620	arg1	concentration					535:547	the concentration	531:547	the concentration of oxyproline, glycosaminoglycans, and catalase activity	531:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	13	from	increase	613:620	arg1	content					629:635	the content	625:635	the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	625:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	14	with	animals	801:807	arg1	syndrome					827:834	chronic pain syndrome	814:834	chronic pain syndrome	814:834	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	3	15	located	found	710:714	arg1	animals					719:725	animals	719:725	animals with experimental periodontitis	719:757	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	15	located	found	710:714	arg2	decrease					519:526	A decrease	517:526	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity	517:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	15	located	found	710:714	arg2	increase					613:620	an increase	610:620	an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	610:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	16	theme	periodontitis	863:875	arg1	modelling					837:845	modelling	837:845	modelling of experimental periodontitis	837:875	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	17	theme	bilateral	273:281	arg1	ligation					283:290	bilateral ligation	273:290	bilateral ligation of the sciatic nerve	273:311	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	1	18	theme	tissue	162:167	arg1	composition					131:141	the composition	127:141	the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome	127:233	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	0	19	theme	Pain	100:103	arg1	Syndrome					105:112	Chronic Pain Syndrome	92:112	Chronic Pain Syndrome	92:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	4	20	theme	experimental	850:861	arg1	periodontitis					863:875	experimental periodontitis	850:875	experimental periodontitis	850:875	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	21	theme	periodontal	1085:1095	arg1	tissue					1097:1102	the periodontal tissue	1081:1102	the periodontal tissue	1081:1102	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	22	theme	ligature	396:403	arg1	application					356:366	application	356:366	application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots	356:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	0	23	from	Composition	29:39	arg1	Rats					64:67	Rats	64:67	Rats with Periodontitis and Chronic Pain Syndrome	64:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	3	24	from	content	629:635	arg1	tissue					698:703	the periodontal tissue	682:703	the periodontal tissue	682:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	2	25	theme	thread	389:394	arg1	ligature					396:403	eight-shaped silk thread ligature	371:403	eight-shaped silk thread ligature	371:403	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	3	26	from	acylhydroperoxides	660:677	arg1	tissue					698:703	the periodontal tissue	682:703	the periodontal tissue	682:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	27	from	activity	1069:1076	arg1	tissue					1097:1102	the periodontal tissue	1081:1102	the periodontal tissue	1081:1102	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	28	theme	nerve	307:311	arg1	ligation					283:290	bilateral ligation	273:290	bilateral ligation of the sciatic nerve	273:311	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	2	29	theme	silk	384:387	arg1	ligature					396:403	eight-shaped silk thread ligature	371:403	eight-shaped silk thread ligature	371:403	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	0	30	theme	Biochemical	17:27	arg1	Composition					29:39	the Biochemical Composition	13:39	the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome	13:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	4	31	theme	glycosaminoglycans	948:965	arg1	concentration					916:928	the concentration	912:928	the concentration of oxyproline and glycosaminoglycans	912:965	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	32	theme	sciatic	299:305	arg1	nerve					307:311	the sciatic nerve	295:311	the sciatic nerve	295:311	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	1	33	theme	experimental	182:193	arg1	periodontitis					195:207	experimental periodontitis	182:207	experimental periodontitis	182:207	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	4	34	theme	catalase	1060:1067	arg1	activity					1069:1076	catalase activity	1060:1076	catalase activity in the periodontal tissue	1060:1102	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	35	from	increase	968:975	arg1	content					984:990	the content	980:990	the content of acylhydroperoxides and malondialdehyde	980:1032	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	35	from	increase	968:975	arg1	activity					1069:1076	catalase activity	1060:1076	catalase activity in the periodontal tissue	1060:1102	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	3	36	theme	glycosaminoglycans	564:581	arg1	concentration					535:547	the concentration	531:547	the concentration of oxyproline, glycosaminoglycans, and catalase activity	531:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	2	37	theme	periodontal	462:472	arg1	groove					474:479	the periodontal groove	458:479	the periodontal groove	458:479	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	3	38	from	decrease	519:526	arg1	concentration					535:547	the concentration	531:547	the concentration of oxyproline, glycosaminoglycans, and catalase activity	531:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	38	from	decrease	519:526	arg1	content					629:635	the content	625:635	the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	625:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	39	from	decrease	1048:1055	arg1	content					984:990	the content	980:990	the content of acylhydroperoxides and malondialdehyde	980:1032	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	39	from	decrease	1048:1055	arg1	activity					1069:1076	catalase activity	1060:1076	catalase activity in the periodontal tissue	1060:1102	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	3	40	theme	acylhydroperoxides	660:677	arg1	content					629:635	the content	625:635	the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	625:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	2	41	theme	Chronic	236:242	arg1	syndrome					249:256	Chronic pain syndrome	236:256	Chronic pain syndrome	236:256	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	2	42	theme	jaw	414:416	arg1	incisors					418:425	lower jaw incisors	408:425	lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots	408:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	0	43	theme	Composition	29:39	arg1	Disorders					0:8	Disorders	0:8	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.	0:113	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	0	44	from	Rats	64:67	arg1	Disorders					0:8	Disorders	0:8	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.	0:113	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	1	45	theme	chronic	213:219	arg1	syndrome					226:233	chronic pain syndrome	213:233	chronic pain syndrome	213:233	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	0	46	theme	Periodontium	48:59	arg1	Composition					29:39	the Biochemical Composition	13:39	the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome	13:112	Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.					
35622257	1	47	with	rats	172:175	arg1	periodontitis					195:207	experimental periodontitis	182:207	experimental periodontitis	182:207	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	1	47	with	rats	172:175	arg1	syndrome					226:233	chronic pain syndrome	213:233	chronic pain syndrome	213:233	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	3	48	theme	malondialdehyde	640:654	arg1	content					629:635	the content	625:635	the content of malondialdehyde and acylhydroperoxides in the periodontal tissue	625:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	49	theme	catalase	588:595	arg1	activity					597:604	catalase activity	588:604	catalase activity	588:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	50	theme	periodontal	686:696	arg1	tissue					698:703	the periodontal tissue	682:703	the periodontal tissue	682:703	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	3	51	theme	activity	597:604	arg1	concentration					535:547	the concentration	531:547	the concentration of oxyproline, glycosaminoglycans, and catalase activity	531:604	A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).					
35622257	4	52	theme	chronic	814:820	arg1	syndrome					827:834	chronic pain syndrome	814:834	chronic pain syndrome	814:834	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	4	53	theme	oxyproline	933:942	arg1	concentration					916:928	the concentration	912:928	the concentration of oxyproline and glycosaminoglycans	912:965	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	54	with	immersion	443:451	arg1	knots					510:514	additional knots	499:514	additional knots	499:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	1	55	theme	pain	221:224	arg1	syndrome					226:233	chronic pain syndrome	213:233	chronic pain syndrome	213:233	We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome.					
35622257	2	56	theme	experimental	314:325	arg1	periodontitis					327:339	experimental periodontitis	314:339	experimental periodontitis	314:339	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	2	57	with	fixation	485:492	arg1	knots					510:514	additional knots	499:514	additional knots	499:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	2	58	theme	lower	408:412	arg1	incisors					418:425	lower jaw incisors	408:425	lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots	408:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	4	59	theme	pain	822:825	arg1	syndrome					827:834	chronic pain syndrome	814:834	chronic pain syndrome	814:834	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	60	theme	eight-shaped	371:382	arg1	ligature					396:403	eight-shaped silk thread ligature	371:403	eight-shaped silk thread ligature	371:403	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	4	61	theme	acylhydroperoxides	995:1012	arg1	content					984:990	the content	980:990	the content of acylhydroperoxides and malondialdehyde	980:1032	In animals with chronic pain syndrome, modelling of experimental periodontitis led to more pronounced decrease in the concentration of oxyproline and glycosaminoglycans, increase in the content of acylhydroperoxides and malondialdehyde, as well as a decrease in catalase activity in the periodontal tissue.					
35622257	2	62	theme	additional	499:508	arg1	knots					510:514	additional knots	499:514	additional knots	499:514	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35622257	2	63	theme	pain	244:247	arg1	syndrome					249:256	Chronic pain syndrome	236:256	Chronic pain syndrome	236:256	Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots.					
35266637	2	0	link	cell-derived	363:374	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	0	link	cell-derived	363:374	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	1	theme	artificial	376:385	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	1	theme	artificial	376:385	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	6	2	theme	macrophage	1243:1252	arg1	polarization					1254:1265	M2 macrophage polarization	1240:1265	M2 macrophage polarization	1240:1265	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	4	3	theme	methacrylated	704:716	arg1	HAMA					735:738	HAMA	735:738	HAMA	735:738	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	4	3	theme	methacrylated	704:716	arg1	acid					729:732	methacrylated hyaluronic acid	704:732	the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips	694:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	5	4	theme	HAMA	887:890	arg1	tips					898:901	HAMA patch tips	887:901	HAMA patch tips	887:901	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	1	5	with	dressing	108:115	arg1	capacities					126:135	the capacities	122:135	the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction	122:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	7	6	theme	diabetic	1394:1401	arg1	healing					1409:1415	diabetic wound healing	1394:1415	diabetic wound healing	1394:1415	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	3	7	theme	HA	608:609	arg1	core					611:614	the inner HA core	598:614	the inner HA core of the MN tips for accelerating angiogenesis	598:659	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	1	8	theme	promoting	238:246	arg1	healing					254:260	effectively promoting wound healing	226:260	effectively promoting wound healing	226:260	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	3	9	theme	MN	623:624	arg1	tips					626:629	the MN tips	619:629	the MN tips for accelerating angiogenesis	619:659	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	1	10	theme	antioxidation	140:152	arg1	capacities					126:135	the capacities	122:135	the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction	122:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	8	11	theme	pro-angiogenesis	1473:1488	arg1	features					1424:1431	These features	1418:1431	These features of antioxidation, antiinflammation, and pro-angiogenesis	1418:1488	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	6	12	theme	PDA	1200:1202	arg1	combination					1185:1195	the combination	1181:1195	the combination of PDA NPs and Fe-MSC-NVs	1181:1221	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	6	13	dep	PDA	1200:1202	arg1	Fe-MSC-NVs					1212:1221	Fe-MSC-NVs	1212:1221	Fe-MSC-NVs	1212:1221	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	6	13	dep	PDA	1200:1202	arg1	NPs					1204:1206	NPs	1204:1206	NPs	1204:1206	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	2	14	theme	hyaluronic	290:299	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	15	theme	PDA	920:922	arg1	NPs					924:926	the PDA NPs	916:926	the PDA NPs	916:926	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	7	16	theme	Fe-MSC-NVs/PDA	1340:1353	arg1	patch					1358:1362	the Fe-MSC-NVs/PDA MN patch	1336:1362	the Fe-MSC-NVs/PDA MN patch	1336:1362	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	4	17	theme	acid	729:732	arg1	shell					741:745	the outer methacrylated hyaluronic acid (HAMA) shell	694:745	the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips	694:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	0	18	theme	Wound	87:91	arg1	Healing					93:99	Wound Healing	87:99	Wound Healing	87:99	Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.					
35266637	5	19	theme	human	1114:1118	arg1	HUVEC					1154:1158	HUVEC	1154:1158	HUVEC	1154:1158	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	19	theme	human	1114:1118	arg1	cells					1147:1151	human umbilical vein endothelial cells	1114:1151	human umbilical vein endothelial cells (HUVEC)	1114:1159	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	2	20	theme	novel	273:277	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	21	theme	tips	898:901	arg1	degradation					872:882	the gradual degradation	860:882	the gradual degradation of HAMA patch tips in the skin	860:913	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	3	22	contain	containing	529:538	arg2	cytokines					568:576	multifunctional therapeutic cytokines	540:576	multifunctional therapeutic cytokines	540:576	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	3	22	contain	containing	529:538	arg1	Fe-MSC-NVs					518:527	Fe-MSC-NVs	518:527	Fe-MSC-NVs containing multifunctional therapeutic cytokines	518:576	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	5	23	theme	vein	1130:1133	arg1	HUVEC					1154:1158	HUVEC	1154:1158	HUVEC	1154:1158	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	23	theme	vein	1130:1133	arg1	cells					1147:1151	human umbilical vein endothelial cells	1114:1151	human umbilical vein endothelial cells (HUVEC)	1114:1159	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	1	24	theme	angiogenesis	187:198	arg1	induction					200:208	efficient angiogenesis induction	177:208	efficient angiogenesis induction	177:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	8	25	theme	MN	1533:1534	arg1	patch					1536:1540	the proposed composite core-shell MN patch	1499:1540	the proposed composite core-shell MN patch is valuable for clinical wound healing applications	1499:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	4	26	theme	adverse	778:784	arg1	impacts					786:792	the adverse impacts	774:792	the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress	774:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	1	27	theme	antiinflammation	155:170	arg1	capacities					126:135	the capacities	122:135	the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction	122:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	1	28	theme	Wound	102:106	arg1	dressing					108:115	Wound dressing	102:115	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction	102:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	4	29	link	-derived	828:835	arg1	stress					847:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	2	30	theme	needle	474:479	arg1	tips					481:484	the needle tips	470:484	the needle tips	470:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	4	31	theme	tips	757:760	arg1	shell					741:745	the outer methacrylated hyaluronic acid (HAMA) shell	694:745	the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips	694:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	8	32	theme	wound	1567:1571	arg1	healing					1573:1579	wound healing	1567:1579	clinical wound healing applications	1558:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	7	33	theme	in	1316:1317	arg1	experiment					1324:1333	in vivo experiment	1316:1333	in vivo experiment	1316:1333	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	2	34	theme	PDA	445:447	arg1	nanoparticles					430:442	polydopamine nanoparticles	417:442	polydopamine nanoparticles (PDA NPs)	417:452	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	34	theme	PDA	445:447	arg1	NPs					449:451	PDA NPs	445:451	PDA NPs	445:451	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	35	theme	gradual	864:870	arg1	degradation					872:882	the gradual degradation	860:882	the gradual degradation of HAMA patch tips in the skin	860:913	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	36	theme	cells	1147:1151	arg1	formation					1101:1109	tube formation	1096:1109	tube formation	1096:1109	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	36	theme	cells	1147:1151	arg1	proliferation					1077:1089	proliferation	1077:1089	proliferation	1077:1089	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	36	theme	cells	1147:1151	arg1	migration					1066:1074	migration	1066:1074	migration	1066:1074	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	0	37	theme	Fe-MSC-Derived	41:54	arg1	Encapsulation					69:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.					
35266637	4	38	theme	oxidative	837:845	arg1	stress					847:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	0	39	with	Microneedles	23:34	arg1	Encapsulation					69:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.					
35266637	2	40	theme	cell-derived	363:374	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	40	theme	cell-derived	363:374	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	4	41	theme	oxygen	808:813	arg1	species					815:821	reactive oxygen species	799:821	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	4	41	theme	oxygen	808:813	arg1	ROS					824:826	ROS	824:826	ROS	824:826	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	2	42	theme	ferrum-mesenchymal	339:356	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	42	theme	ferrum-mesenchymal	339:356	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	8	43	theme	antioxidation	1436:1448	arg1	features					1424:1431	These features	1418:1431	These features of antioxidation, antiinflammation, and pro-angiogenesis	1418:1488	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	3	44	theme	therapeutic	556:566	arg1	cytokines					568:576	multifunctional therapeutic cytokines	540:576	multifunctional therapeutic cytokines	540:576	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	5	45	theme	inflammation	995:1006	arg1	reaction					1008:1015	the ROS-induced inflammation reaction	979:1015	the ROS-induced inflammation reaction	979:1015	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	6	46	theme	wound	1288:1292	arg1	inflammation					1294:1305	wound inflammation	1288:1305	wound inflammation	1288:1305	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	8	47	dep	patch	1536:1540	arg1	valuable					1545:1552	valuable	1545:1552	valuable	1545:1552	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	8	48	theme	composite	1512:1520	arg1	patch					1536:1540	the proposed composite core-shell MN patch	1499:1540	the proposed composite core-shell MN patch is valuable for clinical wound healing applications	1499:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	2	49	theme	microneedle	311:321	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	50	theme	HA	307:308	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	1	51	theme	induction	200:208	arg1	capacities					126:135	the capacities	122:135	the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction	122:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	6	52	theme	M2	1240:1241	arg1	polarization					1254:1265	M2 macrophage polarization	1240:1265	M2 macrophage polarization	1240:1265	More attractively, the combination of PDA NPs and Fe-MSC-NVs further promotes M2 macrophage polarization, thereby suppressing wound inflammation.					
35266637	4	53	theme	outer	698:702	arg1	shell					741:745	the outer methacrylated hyaluronic acid (HAMA) shell	694:745	the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips	694:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	2	54	theme	MN	324:325	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	8	55	theme	antiinflammation	1451:1466	arg1	features					1424:1431	These features	1418:1431	These features of antioxidation, antiinflammation, and pro-angiogenesis	1418:1488	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	7	56	theme	wound	1403:1407	arg1	healing					1409:1415	diabetic wound healing	1394:1415	diabetic wound healing	1394:1415	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	4	57	theme	PDA	666:668	arg1	NPs					670:672	The PDA NPs	662:672	The PDA NPs	662:672	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	3	58	theme	tips	626:629	arg1	core					611:614	the inner HA core	598:614	the inner HA core of the MN tips for accelerating angiogenesis	598:659	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	1	59	theme	wound	248:252	arg1	healing					254:260	effectively promoting wound healing	226:260	effectively promoting wound healing	226:260	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	7	60	theme	excellent	1373:1381	arg1	effect					1383:1388	an excellent effect	1370:1388	an excellent effect for diabetic wound healing	1370:1415	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	2	61	theme	acid	301:304	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	3	62	theme	inner	602:606	arg1	core					611:614	the inner HA core	598:614	the inner HA core of the MN tips for accelerating angiogenesis	598:659	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	8	63	theme	proposed	1503:1510	arg1	patch					1536:1540	the proposed composite core-shell MN patch	1499:1540	the proposed composite core-shell MN patch is valuable for clinical wound healing applications	1499:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	2	64	theme	core-shell	279:288	arg1	patch					328:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch	271:332	a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips	271:484	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	65	theme	patch	892:896	arg1	tips					898:901	HAMA patch tips	887:901	HAMA patch tips	887:901	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	8	66	theme	core-shell	1522:1531	arg1	patch					1536:1540	the proposed composite core-shell MN patch	1499:1540	the proposed composite core-shell MN patch is valuable for clinical wound healing applications	1499:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	7	67	theme	MN	1355:1356	arg1	patch					1358:1362	the Fe-MSC-NVs/PDA MN patch	1336:1362	the Fe-MSC-NVs/PDA MN patch	1336:1362	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	4	68	theme	hyaluronic	718:727	arg1	HAMA					735:738	HAMA	735:738	HAMA	735:738	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	4	68	theme	hyaluronic	718:727	arg1	acid					729:732	methacrylated hyaluronic acid	704:732	the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips	694:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	5	69	theme	umbilical	1120:1128	arg1	HUVEC					1154:1158	HUVEC	1154:1158	HUVEC	1154:1158	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	69	theme	umbilical	1120:1128	arg1	cells					1147:1151	human umbilical vein endothelial cells	1114:1151	human umbilical vein endothelial cells (HUVEC)	1114:1159	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	70	from	degradation	872:882	arg1	skin					910:913	the skin	906:913	the skin	906:913	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	1	71	theme	efficient	177:185	arg1	induction					200:208	efficient angiogenesis induction	177:208	efficient angiogenesis induction	177:208	Wound dressing with the capacities of antioxidation, antiinflammation, and efficient angiogenesis induction is expected for effectively promoting wound healing.					
35266637	2	72	theme	wound	503:507	arg1	healing					509:515	wound healing	503:515	wound healing	503:515	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	73	theme	endothelial	1135:1145	arg1	HUVEC					1154:1158	HUVEC	1154:1158	HUVEC	1154:1158	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	73	theme	endothelial	1135:1145	arg1	cells					1147:1151	human umbilical vein endothelial cells	1114:1151	human umbilical vein endothelial cells (HUVEC)	1114:1159	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	2	74	with	patch	328:332	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	74	with	patch	328:332	arg1	nanoparticles					430:442	polydopamine nanoparticles	417:442	polydopamine nanoparticles (PDA NPs)	417:452	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	74	with	patch	328:332	arg1	NPs					449:451	PDA NPs	445:451	PDA NPs	445:451	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	74	with	patch	328:332	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	5	75	theme	tube	1096:1099	arg1	formation					1101:1109	tube formation	1096:1109	tube formation	1096:1109	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	8	76	theme	clinical	1558:1565	arg1	applications					1581:1592	clinical wound healing applications	1558:1592	clinical wound healing applications	1558:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	2	77	theme	polydopamine	417:428	arg1	nanoparticles					430:442	polydopamine nanoparticles	417:442	polydopamine nanoparticles (PDA NPs)	417:452	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	77	theme	polydopamine	417:428	arg1	NPs					449:451	PDA NPs	445:451	PDA NPs	445:451	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	4	78	from	stress	847:852	arg1	impacts					786:792	the adverse impacts	774:792	the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress	774:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	8	79	theme	healing	1573:1579	arg1	applications					1581:1592	clinical wound healing applications	1558:1592	clinical wound healing applications	1558:1592	These features of antioxidation, antiinflammation, and pro-angiogenesis indicate the proposed composite core-shell MN patch is valuable for clinical wound healing applications.					
35266637	4	80	theme	MN	754:755	arg1	tips					757:760	the MN tips	750:760	the MN tips	750:760	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	0	81	theme	Nanovesicles	56:67	arg1	Encapsulation					69:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Fe-MSC-Derived Nanovesicles Encapsulation	41:81	Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.					
35266637	4	82	theme	-derived	828:835	arg1	stress					847:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	3	83	theme	multifunctional	540:554	arg1	cytokines					568:576	multifunctional therapeutic cytokines	540:576	multifunctional therapeutic cytokines	540:576	Fe-MSC-NVs containing multifunctional therapeutic cytokines are encapsulated in the inner HA core of the MN tips for accelerating angiogenesis.					
35266637	2	84	theme	stem	358:361	arg1	nanovesicles					387:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles	339:398	ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs)	339:411	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	2	84	theme	stem	358:361	arg1	Fe-MSC-NVs					401:410	Fe-MSC-NVs	401:410	Fe-MSC-NVs	401:410	Herein, a novel core-shell hyaluronic acid (HA) microneedle (MN) patch with ferrum-mesenchymal stem cell-derived artificial nanovesicles (Fe-MSC-NVs) and polydopamine nanoparticles (PDA NPs) encapsulated in the needle tips is presented for wound healing.					
35266637	7	85	dep	in	1316:1317	arg1	vivo					1319:1322	vivo	1319:1322	vivo	1319:1322	Through in vivo experiment, the Fe-MSC-NVs/PDA MN patch shows an excellent effect for diabetic wound healing.					
35266637	4	86	theme	reactive	799:806	arg1	species					815:821	reactive oxygen species	799:821	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	4	86	theme	reactive	799:806	arg1	ROS					824:826	ROS	824:826	ROS	824:826	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35266637	5	87	theme	ROS-induced	983:993	arg1	reaction					1008:1015	the ROS-induced inflammation reaction	979:1015	the ROS-induced inflammation reaction	979:1015	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	5	88	dep	migration	1066:1074	arg1	the					1062:1064	the	1062:1064	the	1062:1064	With the gradual degradation of HAMA patch tips in the skin, the PDA NPs are sustainably released at the lesion to suppress the ROS-induced inflammation reaction, while the Fe-MSC-NVs significantly increase the migration, proliferation, and tube formation of human umbilical vein endothelial cells (HUVEC).					
35266637	4	89	theme	species	815:821	arg1	stress					847:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	reactive oxygen species (ROS)-derived oxidative stress	799:852	The PDA NPs are encapsulated in the outer methacrylated hyaluronic acid (HAMA) shell of the MN tips to overcome the adverse impacts from reactive oxygen species (ROS)-derived oxidative stress.					
35930175	1	0	theme	echo	316:319	arg1	intensity					321:329	echo intensity	316:329	echo intensity	316:329	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	2	1	theme	different	568:576	arg1	diameters					578:586	five different diameters	563:586	five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	563:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	4	2	theme	upward	800:805	arg1	position					807:814	an upward position	797:814	an upward position	797:814	Each object was placed onto a chest wall phantom as the plane of the hemisphere was placed in an upward position.					
35930175	6	3	theme	artifacts	982:990	arg1	attenuation					963:973	attenuation	963:973	attenuation of the artifacts in the objects made of agar containing graphite	963:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	3	theme	artifacts	982:990	arg1	sizes					938:942	all sizes	934:942	all sizes	934:942	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	3	theme	artifacts	982:990	arg1	intensity					949:957	the intensity	945:957	the intensity	945:957	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	4	contain	containing	1020:1029	arg2	graphite					1031:1038	graphite	1031:1038	graphite	1031:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	4	contain	containing	1020:1029	arg1	agar					1015:1018	agar	1015:1018	agar containing graphite	1015:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	8	5	from	ultrasound	1427:1436	arg1	sources					1389:1395	sources	1389:1395	sources of vertical artifacts in lung ultrasound	1389:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	4	6	theme	hemisphere	772:781	arg1	plane					759:763	the plane	755:763	the plane of the hemisphere	755:781	Each object was placed onto a chest wall phantom as the plane of the hemisphere was placed in an upward position.					
35930175	0	7	theme	artifacts	85:93	arg1	configuration					59:71	the configuration	55:71	the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models	55:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	8	8	theme	lung	1422:1425	arg1	ultrasound					1427:1436	lung ultrasound	1422:1436	lung ultrasound	1422:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	6	9	from	intensity	949:957	arg1	objects					999:1005	the objects	995:1005	the objects made of agar containing graphite	995:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	5	10	theme	artifact	859:866	arg1	attenuation					840:850	attenuation	840:850	attenuation	840:850	The echo intensity and attenuation of the artifact generated from each object was measured and compared.					
35930175	5	10	theme	artifact	859:866	arg1	intensity					826:834	echo intensity	821:834	echo intensity	821:834	The echo intensity and attenuation of the artifact generated from each object was measured and compared.					
35930175	0	11	with	study	131:135	arg1	models					149:154	simple models	142:154	simple models	142:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	0	12	theme	vertical	76:83	arg1	artifacts					85:93	vertical artifacts	76:93	vertical artifacts in lung ultrasound: an experimental study with simple models	76:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	3	13	theme	gel	648:650	arg1	object					652:657	each hemispherical gel object	629:657	each hemispherical gel object	629:657	Ten of each hemispherical gel object were prepared for the statistical analyses.					
35930175	0	14	theme	lung	98:101	arg1	ultrasound					103:112	lung ultrasound	98:112	lung ultrasound	98:112	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	3	15	theme	object	652:657	arg1	Ten					622:624	Ten	622:624	Ten	622:624	Ten of each hemispherical gel object were prepared for the statistical analyses.					
35930175	3	15	theme	object	652:657	arg1	object					652:657	each hemispherical gel object	629:657	each hemispherical gel object	629:657	Ten of each hemispherical gel object were prepared for the statistical analyses.					
35930175	6	16	from	attenuation	963:973	arg1	objects					999:1005	the objects	995:1005	the objects made of agar containing graphite	995:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	0	17	dep	artifacts	85:93	arg1	study					131:135	an experimental study	115:135	vertical artifacts in lung ultrasound: an experimental study with simple models	76:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	8	18	from	sources	1389:1395	arg1	ultrasound					1427:1436	lung ultrasound	1422:1436	lung ultrasound	1422:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	1	19	theme	artifacts	350:358	arg1	intensity					321:329	echo intensity	316:329	echo intensity	316:329	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	1	19	theme	artifacts	350:358	arg1	attenuation					335:345	attenuation	335:345	attenuation	335:345	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	8	20	from	artifacts	1409:1417	arg1	ultrasound					1427:1436	lung ultrasound	1422:1436	lung ultrasound	1422:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	2	21	dep	diameters	578:586	arg1	9.5					604:606	9.5	604:606	9.5	604:606	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	21	dep	diameters	578:586	arg1	11.4 mm					612:618	11.4 mm	612:618	11.4 mm	612:618	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	3	22	theme	statistical	681:691	arg1	analyses					693:700	the statistical analyses	677:700	the statistical analyses	677:700	Ten of each hemispherical gel object were prepared for the statistical analyses.					
35930175	2	23	theme	gel	429:431	arg1	sources					372:378	sources	372:378	sources of artifacts	372:391	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	23	theme	gel	429:431	arg1	objects					433:439	10 different hemispherical gel objects	402:439	10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	402:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	3	24	theme	hemispherical	634:646	arg1	object					652:657	each hemispherical gel object	629:657	each hemispherical gel object	629:657	Ten of each hemispherical gel object were prepared for the statistical analyses.					
35930175	6	25	theme	pure	1125:1128	arg1	agar					1130:1133	pure agar	1125:1133	pure agar	1125:1133	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	1	26	theme	attenuation	256:266	arg1	relationship					236:247	the relationship	232:247	the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts	232:358	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	2	27	dep	mediums	460:466	arg1	agar					482:485	agar	482:485	agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz	482:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	27	dep	mediums	460:466	arg1	mediums					460:466	two different mediums	446:466	two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz)	446:557	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	27	dep	mediums	460:466	arg1	agar					474:477	pure agar	469:477	pure agar	469:477	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	28	theme	hemispherical	415:427	arg1	sources					372:378	sources	372:378	sources of artifacts	372:391	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	28	theme	hemispherical	415:427	arg1	objects					433:439	10 different hemispherical gel objects	402:439	10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	402:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	1	29	dep	intensity	321:329	arg1	the					312:314	the	312:314	the	312:314	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	1	30	theme	simple	171:176	arg1	models					191:196	simple experimental models	171:196	simple experimental models for lung ultrasound	171:216	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	0	31	theme	attenuation	14:24	arg1	effect					4:9	The effect	0:9	The effect of attenuation	0:24	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	8	32	theme	physical	1365:1372	arg1	composition					1374:1384	the physical composition	1361:1384	the physical composition of sources of vertical artifacts in lung ultrasound	1361:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	1	33	theme	experimental	178:189	arg1	models					191:196	simple experimental models	171:196	simple experimental models for lung ultrasound	171:216	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	8	34	theme	sources	1389:1395	arg1	composition					1374:1384	the physical composition	1361:1384	the physical composition of sources of vertical artifacts in lung ultrasound	1361:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	2	35	theme	attenuation	515:525	arg1	coefficient					527:537	an attenuation coefficient	512:537	an attenuation coefficient of 0.5 dB/cm · MHz	512:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	4	36	dep	wall	739:742	arg1	phantom					744:750	phantom	744:750	phantom	744:750	Each object was placed onto a chest wall phantom as the plane of the hemisphere was placed in an upward position.					
35930175	2	37	theme	different	450:458	arg1	agar					482:485	agar	482:485	agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz	482:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	37	theme	different	450:458	arg1	mediums					460:466	two different mediums	446:466	two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz)	446:557	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	37	theme	different	450:458	arg1	agar					474:477	pure agar	469:477	pure agar	469:477	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	0	38	theme	experimental	118:129	arg1	study					131:135	an experimental study	115:135	vertical artifacts in lung ultrasound: an experimental study with simple models	76:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	0	39	from	configuration	59:71	arg1	ultrasound					103:112	lung ultrasound	98:112	lung ultrasound	98:112	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	4	40	theme	chest	733:737	arg1	wall					739:742	a chest wall	731:742	a chest wall phantom as the plane of the hemisphere was placed in an upward position	731:814	Each object was placed onto a chest wall phantom as the plane of the hemisphere was placed in an upward position.					
35930175	8	41	theme	vertical	1324:1331	arg1	artifacts					1333:1341	vertical artifacts	1324:1341	vertical artifacts	1324:1341	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	2	42	theme	different	405:413	arg1	sources					372:378	sources	372:378	sources of artifacts	372:391	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	42	theme	different	405:413	arg1	objects					433:439	10 different hemispherical gel objects	402:439	10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	402:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	1	43	theme	lung	202:205	arg1	ultrasound					207:216	lung ultrasound	202:216	lung ultrasound	202:216	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	1	44	theme	vertical	290:297	arg1	artifacts					299:307	vertical artifacts	290:307	vertical artifacts	290:307	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	2	45	theme	MHz	554:556	arg1	coefficient					527:537	an attenuation coefficient	512:537	an attenuation coefficient of 0.5 dB/cm · MHz	512:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	6	46	from	objects	999:1005	arg1	attenuation					963:973	attenuation	963:973	attenuation of the artifacts in the objects made of agar containing graphite	963:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	46	from	objects	999:1005	arg1	sizes					938:942	all sizes	934:942	all sizes	934:942	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	6	46	from	objects	999:1005	arg1	intensity					949:957	the intensity	945:957	the intensity	945:957	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	8	47	dep	intensity	1295:1303	arg1	the					1291:1293	the	1291:1293	the	1291:1293	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	8	48	theme	artifacts	1409:1417	arg1	sources					1389:1395	sources	1389:1395	sources of vertical artifacts in lung ultrasound	1389:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	1	49	theme	artifacts	299:307	arg1	sources					279:285	the sources	275:285	the sources of vertical artifacts	275:307	PURPOSE Using simple experimental models for lung ultrasound, we evaluated the relationship of the attenuation inside the sources of vertical artifacts to the echo intensity and attenuation of artifacts.					
35930175	2	50	theme	·	552:552	arg1	MHz					554:556	0.5 dB/cm · MHz	542:556	0.5 dB/cm · MHz	542:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	0	51	dep	inside	26:31	arg1	traps					46:50	traps	46:50	inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models	26:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	8	52	theme	vertical	1400:1407	arg1	artifacts					1409:1417	vertical artifacts	1400:1417	vertical artifacts in lung ultrasound	1400:1436	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	2	53	theme	0.5 dB/cm	542:550	arg1	MHz					554:556	0.5 dB/cm · MHz	542:556	0.5 dB/cm · MHz	542:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	8	54	theme	artifacts	1333:1341	arg1	attenuation					1309:1319	attenuation	1309:1319	attenuation	1309:1319	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	8	54	theme	artifacts	1333:1341	arg1	intensity					1295:1303	intensity	1295:1303	intensity	1295:1303	CONCLUSION Based on this experiment, assessing the intensity and attenuation of vertical artifacts may help estimate the physical composition of sources of vertical artifacts in lung ultrasound.					
35930175	5	55	theme	echo	821:824	arg1	intensity					826:834	echo intensity	821:834	echo intensity	821:834	The echo intensity and attenuation of the artifact generated from each object was measured and compared.					
35930175	0	56	theme	simple	142:147	arg1	models					149:154	simple models	142:154	simple models	142:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	0	57	from	artifacts	85:93	arg1	ultrasound					103:112	lung ultrasound	98:112	lung ultrasound	98:112	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35930175	2	58	dep	METHODS	361:367	arg1	made					397:400	made	397:400	made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	397:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	6	59	from	artifacts	982:990	arg1	objects					999:1005	the objects	995:1005	the objects made of agar containing graphite	995:1038	RESULTS For all sizes, the intensity and attenuation of the artifacts in the objects made of agar containing graphite were significantly lower and larger, respectively, than those in the objects made of pure agar.					
35930175	2	60	theme	artifacts	383:391	arg1	sources					372:378	sources	372:378	sources of artifacts	372:391	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	60	theme	artifacts	383:391	arg1	objects					433:439	10 different hemispherical gel objects	402:439	10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	402:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	61	with	objects	433:439	arg1	agar					482:485	agar	482:485	agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz	482:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	61	with	objects	433:439	arg1	mediums					460:466	two different mediums	446:466	two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz)	446:557	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	61	with	objects	433:439	arg1	agar					474:477	pure agar	469:477	pure agar	469:477	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	61	with	objects	433:439	arg1	diameters					578:586	five different diameters	563:586	five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm)	563:619	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	7	62	dep	9 MHz	1237:1241	arg1	to					1234:1235	to	1234:1235	to	1234:1235	In the objects containing graphite, the intensity decreased when the frequency was changed from 5 to 9 MHz.					
35930175	2	63	theme	pure	469:472	arg1	mediums					460:466	two different mediums	446:466	two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz)	446:557	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	63	theme	pure	469:472	arg1	agar					474:477	pure agar	469:477	pure agar	469:477	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	7	64	contain	containing	1151:1160	arg2	graphite					1162:1169	graphite	1162:1169	graphite	1162:1169	In the objects containing graphite, the intensity decreased when the frequency was changed from 5 to 9 MHz.					
35930175	7	64	contain	containing	1151:1160	arg1	objects					1143:1149	the objects	1139:1149	the objects containing graphite	1139:1169	In the objects containing graphite, the intensity decreased when the frequency was changed from 5 to 9 MHz.					
35930175	2	65	contain	containing	487:496	arg2	graphite					498:505	graphite	498:505	graphite	498:505	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	65	contain	containing	487:496	arg1	agar					482:485	agar	482:485	agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz	482:556	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	2	65	contain	containing	487:496	arg1	mediums					460:466	two different mediums	446:466	two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz)	446:557	METHODS As sources of artifacts, we made 10 different hemispherical gel objects with two different mediums (pure agar or agar containing graphite with an attenuation coefficient of 0.5 dB/cm · MHz) and five different diameters (3.6, 5.6, 7.5, 9.5, or 11.4 mm).					
35930175	0	66	from	ultrasound	103:112	arg1	configuration					59:71	the configuration	55:71	the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models	55:154	The effect of attenuation inside the acoustic traps on the configuration of vertical artifacts in lung ultrasound: an experimental study with simple models.					
35094516	3	0	with	hyaluronate	599:609	arg1	proportions					650:660	different proportions	640:660	different proportions	640:660	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	9	1	theme	implant	1691:1697	arg1	materials					1699:1707	implant materials	1691:1707	implant materials for osteochondral reconstruction	1691:1740	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	9	1	theme	implant	1691:1697	arg1	scaffolds					1666:1674	the heterogeneous multilayer scaffolds	1637:1674	the heterogeneous multilayer scaffolds	1637:1674	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	1	2	theme	Heterogeneous	159:171	arg1	scaffolds					185:193	Heterogeneous three-layer scaffolds	159:193	Heterogeneous three-layer scaffolds	159:193	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	3	theme	hyaline	273:279	arg1	cartilage					281:289	the hyaline cartilage	269:289	the hyaline cartilage	269:289	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	7	4	theme	osteochondral	1386:1398	arg1	tissue					1400:1405	the osteochondral tissue	1382:1405	the osteochondral tissue	1382:1405	The scaffolds could remain at 50-75% after 30 days of degradation owing to crosslinking, providing enough time for the regeneration of the osteochondral tissue.					
35094516	8	5	theme	bone	1555:1558	arg1	layer					1560:1564	the subchondral bone layer	1539:1564	the subchondral bone layer	1539:1564	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	8	5	theme	bone	1555:1558	arg1	conducive					1575:1583	conducive	1575:1583	conducive	1575:1583	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	1	6	theme	three-layer	173:183	arg1	scaffolds					185:193	Heterogeneous three-layer scaffolds	159:193	Heterogeneous three-layer scaffolds	159:193	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	7	theme	cartilage	281:289	arg1	structure					256:264	structure	256:264	structure	256:264	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	7	theme	cartilage	281:289	arg1	composition					240:250	biochemical composition	228:250	biochemical composition	228:250	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	0	8	theme	Three-Layer	97:107	arg1	Scaffold					109:116	a Heterogeneous Three-Layer Scaffold	81:116	a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects	81:156	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	1	9	dep	composition	240:250	arg1	the					224:226	the	224:226	the	224:226	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	9	10	theme	heterogeneous	1641:1653	arg1	materials					1699:1707	implant materials	1691:1707	implant materials for osteochondral reconstruction	1691:1740	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	9	10	theme	heterogeneous	1641:1653	arg1	scaffolds					1666:1674	the heterogeneous multilayer scaffolds	1637:1674	the heterogeneous multilayer scaffolds	1637:1674	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	4	11	theme	amine	798:802	arg1	collagen					814:821	collagen	814:821	collagen	814:821	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	4	11	theme	amine	798:802	arg1	groups					804:809	the amine groups	794:809	the amine groups of collagen	794:821	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	8	12	theme	cartilage	1462:1470	arg1	layer					1472:1476	calcified cartilage layer	1452:1476	calcified cartilage layer	1452:1476	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	0	13	theme	Heterogeneous	83:95	arg1	Scaffold					109:116	a Heterogeneous Three-Layer Scaffold	81:116	a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects	81:156	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	9	14	theme	osteochondral	1713:1725	arg1	reconstruction					1727:1740	osteochondral reconstruction	1713:1740	osteochondral reconstruction	1713:1740	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	6	15	theme	cellular	1210:1217	arg1	adhesion					1219:1226	cellular adhesion	1210:1226	cellular adhesion	1210:1226	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	1	16	theme	calcified	292:300	arg1	cartilage					302:310	calcified cartilage	292:310	calcified cartilage	292:310	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	3	17	with	collagen	580:587	arg1	proportions					650:660	different proportions	640:660	different proportions	640:660	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	1	18	theme	osteochondral	380:392	arg1	defects					394:400	osteochondral defects	380:400	osteochondral defects	380:400	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	4	19	used	used	749:752	arg2	hydrochloride					731:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride	663:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride	663:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	3	20	theme	calcified	510:518	arg1	layer					530:534	The calcified cartilage layer	506:534	The calcified cartilage layer	506:534	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	5	21	theme	cartilage	909:917	arg1	layer					889:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	21	theme	cartilage	909:917	arg1	structures					948:957	dense structures	942:957	dense structures	942:957	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	21	theme	cartilage	909:917	arg1	layer					919:923	calcified cartilage layer	899:923	calcified cartilage layer	899:923	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	6	22	theme	porous	1129:1134	arg1	structure					1136:1144	a uniform and interconnected porous structure	1100:1144	a uniform and interconnected porous structure	1100:1144	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	1	23	theme	defects	394:400	arg1	repair					370:375	the repair	366:375	the repair of osteochondral defects	366:400	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	3	24	theme	cartilage	520:528	arg1	layer					530:534	The calcified cartilage layer	506:534	The calcified cartilage layer	506:534	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	8	25	theme	hyaline	1424:1430	arg1	layer					1442:1446	the hyaline cartilage layer	1420:1446	the hyaline cartilage layer	1420:1446	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	2	26	theme	cartilage	415:423	arg1	layer					425:429	The hyaline cartilage layer	403:429	The hyaline cartilage layer	403:429	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	2	27	theme	wt	464:465	arg1	%					467:467	50.0 wt %	459:467	50.0 wt %	459:467	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	2	27	theme	wt	464:465	arg1	collagen					447:454	collagen I	447:456	collagen I (50.0 wt %)	447:468	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	4	28	theme	crosslinking	769:780	arg1	reaction					782:789	the crosslinking reaction	765:789	the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate	765:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	2	29	theme	hyaline	407:413	arg1	layer					425:429	The hyaline cartilage layer	403:429	The hyaline cartilage layer	403:429	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	4	30	theme	collagen	814:821	arg1	collagen					814:821	collagen	814:821	collagen	814:821	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	4	30	theme	collagen	814:821	arg1	groups					804:809	the amine groups	794:809	the amine groups of collagen	794:821	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	1	31	theme	cartilage	302:310	arg1	structure					256:264	structure	256:264	structure	256:264	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	31	theme	cartilage	302:310	arg1	composition					240:250	biochemical composition	228:250	biochemical composition	228:250	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	5	32	theme	bone	982:985	arg1	layer					987:991	the subchondral bone layer	966:991	the subchondral bone layer	966:991	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	32	theme	bone	982:985	arg1	structure					1028:1036	a relatively loose structure	1009:1036	a relatively loose structure	1009:1036	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	4	33	theme	-N'-ethylcarbodiimide	709:729	arg1	hydrochloride					731:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride	663:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride	663:743	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	5	34	theme	cartilage	879:887	arg1	layer					889:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	34	theme	cartilage	879:887	arg1	structures					948:957	dense structures	942:957	dense structures	942:957	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	34	theme	cartilage	879:887	arg1	layer					919:923	calcified cartilage layer	899:923	calcified cartilage layer	899:923	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	6	35	theme	interconnected	1114:1127	arg1	structure					1136:1144	a uniform and interconnected porous structure	1100:1144	a uniform and interconnected porous structure	1100:1144	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	8	36	theme	cartilage	1432:1440	arg1	layer					1442:1446	the hyaline cartilage layer	1420:1446	the hyaline cartilage layer	1420:1446	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	3	37	theme	subchondral	540:550	arg1	layer					557:561	subchondral bone layer	540:561	subchondral bone layer	540:561	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	3	38	with	nanohydroxyapatite	616:633	arg1	proportions					650:660	different proportions	640:660	different proportions	640:660	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	4	39	theme	carboxyl	828:835	arg1	groups					837:842	carboxyl groups	828:842	carboxyl groups of sodium hyaluronate	828:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	4	39	theme	carboxyl	828:835	arg1	hyaluronate					854:864	sodium hyaluronate	847:864	sodium hyaluronate	847:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	3	40	theme	bone	552:555	arg1	layer					557:561	subchondral bone layer	540:561	subchondral bone layer	540:561	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	5	41	theme	hyaline	871:877	arg1	layer					889:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	41	theme	hyaline	871:877	arg1	structures					948:957	dense structures	942:957	dense structures	942:957	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	41	theme	hyaline	871:877	arg1	layer					919:923	calcified cartilage layer	899:923	calcified cartilage layer	899:923	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	2	42	theme	sodium	474:479	arg1	hyaluronate					481:491	sodium hyaluronate	474:491	sodium hyaluronate (50.0 wt %)	474:503	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	2	42	theme	sodium	474:479	arg1	%					502:502	50.0 wt %	494:502	50.0 wt %	494:502	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	1	43	theme	subchondral	317:327	arg1	bone					329:332	subchondral bone	317:332	subchondral bone of the osteochondral tissue	317:360	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	0	44	theme	Osteochondral	136:148	arg1	Defects					150:156	Osteochondral Defects	136:156	Osteochondral Defects	136:156	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	3	45	theme	different	640:648	arg1	proportions					650:660	different proportions	640:660	different proportions	640:660	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	4	46	theme	sodium	847:852	arg1	hyaluronate					854:864	sodium hyaluronate	847:864	sodium hyaluronate	847:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	6	47	theme	uniform	1102:1108	arg1	structure					1136:1144	a uniform and interconnected porous structure	1100:1144	a uniform and interconnected porous structure	1100:1144	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	1	48	theme	biochemical	228:238	arg1	composition					240:250	biochemical composition	228:250	biochemical composition	228:250	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	49	theme	bone	329:332	arg1	structure					256:264	structure	256:264	structure	256:264	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	49	theme	bone	329:332	arg1	composition					240:250	biochemical composition	228:250	biochemical composition	228:250	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	5	50	theme	crosslinking	1055:1066	arg1	degree					1068:1073	the crosslinking degree	1051:1073	the crosslinking degree	1051:1073	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	0	51	theme	Osteochondral	47:59	arg1	Tissue					61:66	the Osteochondral Tissue	43:66	the Osteochondral Tissue	43:66	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	4	52	with	reaction	782:789	arg1	groups					837:842	carboxyl groups	828:842	carboxyl groups of sodium hyaluronate	828:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	4	52	with	reaction	782:789	arg1	hyaluronate					854:864	sodium hyaluronate	847:864	sodium hyaluronate	847:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	7	53	theme	tissue	1400:1405	arg1	regeneration					1366:1377	the regeneration	1362:1377	the regeneration of the osteochondral tissue	1362:1405	The scaffolds could remain at 50-75% after 30 days of degradation owing to crosslinking, providing enough time for the regeneration of the osteochondral tissue.					
35094516	7	54	theme	degradation	1301:1311	arg1	days					1293:1296	30 days	1290:1296	30 days of degradation owing to crosslinking	1290:1333	The scaffolds could remain at 50-75% after 30 days of degradation owing to crosslinking, providing enough time for the regeneration of the osteochondral tissue.					
35094516	8	55	theme	subchondral	1543:1553	arg1	layer					1560:1564	the subchondral bone layer	1539:1564	the subchondral bone layer	1539:1564	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	8	55	theme	subchondral	1543:1553	arg1	conducive					1575:1583	conducive	1575:1583	conducive	1575:1583	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	0	56	theme	Defects	150:156	arg1	Repair					126:131	the Repair	122:131	the Repair of Osteochondral Defects	122:156	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	4	57	theme	hyaluronate	854:864	arg1	groups					837:842	carboxyl groups	828:842	carboxyl groups of sodium hyaluronate	828:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	4	57	theme	hyaluronate	854:864	arg1	hyaluronate					854:864	sodium hyaluronate	847:864	sodium hyaluronate	847:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	1	58	theme	osteochondral	341:353	arg1	tissue					355:360	the osteochondral tissue	337:360	the osteochondral tissue	337:360	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	5	59	theme	subchondral	970:980	arg1	bone					982:985	the subchondral bone	966:985	the subchondral bone layer	966:991	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	8	60	theme	calcified	1452:1460	arg1	layer					1472:1476	calcified cartilage layer	1452:1476	calcified cartilage layer	1452:1476	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	5	61	theme	loose	1022:1026	arg1	layer					987:991	the subchondral bone layer	966:991	the subchondral bone layer	966:991	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	61	theme	loose	1022:1026	arg1	structure					1028:1036	a relatively loose structure	1009:1036	a relatively loose structure	1009:1036	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	62	theme	dense	942:946	arg1	layer					889:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	62	theme	dense	942:946	arg1	structures					948:957	dense structures	942:957	dense structures	942:957	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	62	theme	dense	942:946	arg1	layer					919:923	calcified cartilage layer	899:923	calcified cartilage layer	899:923	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	4	63	theme	groups	804:809	arg1	reaction					782:789	the crosslinking reaction	765:789	the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate	765:864	N-Hydroxysuccinimide/N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride was used to mediate the crosslinking reaction of the amine groups of collagen with carboxyl groups of sodium hyaluronate.					
35094516	6	64	contain	possessed	1150:1158	arg2	porosity					1167:1174	a high porosity	1160:1174	a high porosity	1160:1174	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	6	64	contain	possessed	1150:1158	arg1	scaffolds					1080:1088	The scaffolds	1076:1088	The scaffolds	1076:1088	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	6	64	contain	possessed	1150:1158	arg2	conducive					1197:1205	conducive	1197:1205	conducive	1197:1205	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	0	65	dep	Composition	14:24	arg1	the					10:12	the	10:12	the	10:12	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	6	66	theme	high	1162:1165	arg1	porosity					1167:1174	a high porosity	1160:1174	a high porosity	1160:1174	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	6	66	theme	high	1162:1165	arg1	conducive					1197:1205	conducive	1197:1205	conducive	1197:1205	The scaffolds displayed a uniform and interconnected porous structure and possessed a high porosity over 85%, which were conducive to cellular adhesion and proliferation.					
35094516	2	67	theme	wt	499:500	arg1	hyaluronate					481:491	sodium hyaluronate	474:491	sodium hyaluronate (50.0 wt %)	474:503	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	2	67	theme	wt	499:500	arg1	%					502:502	50.0 wt %	494:502	50.0 wt %	494:502	The hyaline cartilage layer was composed of collagen I (50.0 wt %) and sodium hyaluronate (50.0 wt %).					
35094516	8	68	theme	chondrocytes	1519:1530	arg1	proliferation					1502:1514	the proliferation	1498:1514	the proliferation of chondrocytes	1498:1530	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
35094516	5	69	theme	calcified	899:907	arg1	layer					889:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer	867:893	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	69	theme	calcified	899:907	arg1	structures					948:957	dense structures	942:957	dense structures	942:957	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	5	69	theme	calcified	899:907	arg1	layer					919:923	calcified cartilage layer	899:923	calcified cartilage layer	899:923	The hyaline cartilage layer and calcified cartilage layer were designed as dense structures, while the subchondral bone layer was designed as a relatively loose structure by adjusting the crosslinking degree.					
35094516	0	70	theme	Tissue	61:66	arg1	Composition					14:24	Composition	14:24	Composition	14:24	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	0	70	theme	Tissue	61:66	arg1	Structure					30:38	Structure	30:38	Structure	30:38	Mimicking the Composition and Structure of the Osteochondral Tissue to Fabricate a Heterogeneous Three-Layer Scaffold for the Repair of Osteochondral Defects.					
35094516	1	71	theme	tissue	355:360	arg1	cartilage					281:289	the hyaline cartilage	269:289	the hyaline cartilage	269:289	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	71	theme	tissue	355:360	arg1	cartilage					302:310	calcified cartilage	292:310	calcified cartilage	292:310	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	1	71	theme	tissue	355:360	arg1	bone					329:332	subchondral bone	317:332	subchondral bone of the osteochondral tissue	317:360	Heterogeneous three-layer scaffolds were fabricated by mimicking the biochemical composition and structure of the hyaline cartilage, calcified cartilage, and subchondral bone of the osteochondral tissue for the repair of osteochondral defects.					
35094516	3	72	theme	sodium	592:597	arg1	hyaluronate					599:609	sodium hyaluronate	592:609	sodium hyaluronate	592:609	The calcified cartilage layer and subchondral bone layer were composed of collagen I, sodium hyaluronate, and nanohydroxyapatite with different proportions.					
35094516	9	73	theme	multilayer	1655:1664	arg1	materials					1699:1707	implant materials	1691:1707	implant materials for osteochondral reconstruction	1691:1740	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	9	73	theme	multilayer	1655:1664	arg1	scaffolds					1666:1674	the heterogeneous multilayer scaffolds	1637:1674	the heterogeneous multilayer scaffolds	1637:1674	In conclusion, the heterogeneous multilayer scaffolds could serve as implant materials for osteochondral reconstruction.					
35094516	8	74	theme	osteoblasts	1609:1619	arg1	proliferation					1592:1604	the proliferation	1588:1604	the proliferation of osteoblasts	1588:1619	Especially, the hyaline cartilage layer and calcified cartilage layer preferred to induce the proliferation of chondrocytes, while the subchondral bone layer was more conducive to the proliferation of osteoblasts.					
36940872	1	0	theme	herbal	140:145	arg1	waste					147:151	herbal waste	140:151	herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment	140:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	5	1	theme	biological	1017:1026	arg1	treatment					1028:1036	the subsequent biological treatment	1002:1036	the subsequent biological treatment of herbal waste	1002:1052	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	5	2	theme	waste	1048:1052	arg1	treatment					1028:1036	the subsequent biological treatment	1002:1036	the subsequent biological treatment of herbal waste	1002:1052	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	4	3	theme	SEM	649:651	arg1	analysis					653:660	SEM analysis	649:660	SEM analysis	649:660	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	5	4	theme	herbal	852:857	arg1	composition					859:869	the herbal composition	848:869	the herbal composition	848:869	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	4	5	theme	herbal	773:778	arg1	waste					780:784	herbal waste	773:784	herbal waste	773:784	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	1	6	theme	hydrodynamic	61:72	arg1	HC					86:87	HC	86:87	HC	86:87	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	1	6	theme	hydrodynamic	61:72	arg1	cavitation					74:83	hydrodynamic cavitation	61:83	hydrodynamic cavitation (HC)	61:88	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	1	7	theme	waste	147:151	arg1	biodegradability					120:135	the biodegradability	116:135	the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment	116:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	1	8	theme	cavitation	74:83	arg1	effect					51:56	The effect	47:56	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment	47:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	2	9	theme	0.11	354:357	arg1	number					344:349	the cavitation number	329:349	the cavitation number of 0.11	329:357	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	2	10	theme	cavitation	407:416	arg1	zone					418:421	the cavitation zone	403:421	the cavitation zone amounted to 30.5	403:438	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	5	11	theme	structural	881:890	arg1	morphology					892:901	their structural morphology	875:901	their structural morphology	875:901	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	4	12	theme	component	610:618	arg1	analysis					620:627	Fiber component analysis	604:627	Fiber component analysis	604:627	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	4	13	theme	waste	780:784	arg1	structure					760:768	the chemical and morphological structure	729:768	the chemical and morphological structure of herbal waste	729:784	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	2	14	theme	inlet	288:292	arg1	pressure					294:301	an optimal inlet pressure	277:301	an optimal inlet pressure equal to 3.5 bar	277:318	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	1	15	theme	municipal	166:174	arg1	wastewater					176:185	municipal wastewater	166:185	municipal wastewater subjected to mechanical pre-treatment	166:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	0	16	theme	waste	23:27	arg1	Pretreatment					0:11	Pretreatment	0:11	Pretreatment of herbal waste	0:27	Pretreatment of herbal waste using sonication.					
36940872	2	17	theme	optimal	280:286	arg1	pressure					294:301	an optimal inlet pressure	277:301	an optimal inlet pressure equal to 3.5 bar	277:318	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	2	18	theme	recirculation	374:386	arg1	number					364:369	the number	360:369	the number of recirculation	360:386	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	3	19	theme	10th	510:513	arg1	minute					515:520	the 5th and 10th minute	498:520	the 5th and 10th minute of the process	498:535	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	3	20	theme	herbal	582:587	arg1	waste					589:593	herbal waste	582:593	herbal waste	582:593	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	3	21	theme	5th	502:504	arg1	minute					515:520	the 5th and 10th minute	498:520	the 5th and 10th minute of the process	498:535	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	3	22	theme	waste	589:593	arg1	biodegradability					562:577	the enhanced biodegradability	549:577	the enhanced biodegradability of herbal waste	549:593	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	4	23	theme	Fiber	604:608	arg1	analysis					620:627	Fiber component analysis	604:627	Fiber component analysis	604:627	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	3	24	theme	process	529:535	arg1	minute					515:520	the 5th and 10th minute	498:520	the 5th and 10th minute of the process	498:535	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	1	25	theme	mechanical	200:209	arg1	pre-treatment					211:223	mechanical pre-treatment	200:223	mechanical pre-treatment	200:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	5	26	theme	herbal	1041:1046	arg1	waste					1048:1052	herbal waste	1041:1052	herbal waste	1041:1052	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	3	27	theme	BOD5/COD	445:452	arg1	ratio					454:458	The BOD5/COD ratio	441:458	The BOD5/COD ratio	441:458	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	4	28	theme	morphological	746:758	arg1	structure					760:768	the chemical and morphological structure	729:768	the chemical and morphological structure of herbal waste	729:784	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	1	29	theme	manner	98:103	arg1	effect					51:56	The effect	47:56	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment	47:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	5	30	theme	lignin	943:948	arg1	content					950:956	lignin content	943:956	lignin content	943:956	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	4	31	theme	chemical	733:740	arg1	structure					760:768	the chemical and morphological structure	729:768	the chemical and morphological structure of herbal waste	729:784	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
36940872	5	32	theme	hydrodynamic	805:816	arg1	cavitation					818:827	hydrodynamic cavitation	805:827	hydrodynamic cavitation	805:827	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	1	33	dep	manner	98:103	arg1	affects					108:114	affects	108:114	affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment	108:223	The effect of hydrodynamic cavitation (HC) and the manner it affects the biodegradability of herbal waste suspended on municipal wastewater subjected to mechanical pre-treatment was examined in this paper.					
36940872	3	34	theme	enhanced	553:560	arg1	biodegradability					562:577	the enhanced biodegradability	549:577	the enhanced biodegradability of herbal waste	549:593	The BOD5/COD ratio was enhanced by more than 70% between the 5th and 10th minute of the process, indicating the enhanced biodegradability of herbal waste shortly.					
36940872	2	35	theme	equal	303:307	arg1	pressure					294:301	an optimal inlet pressure	277:301	an optimal inlet pressure equal to 3.5 bar	277:318	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	5	36	theme	subsequent	1006:1015	arg1	treatment					1028:1036	the subsequent biological treatment	1002:1036	the subsequent biological treatment of herbal waste	1002:1052	It confirmed that hydrodynamic cavitation visibly influenced the herbal composition and their structural morphology, decreased hemicellulose, cellulose and lignin content, but did not form the by-products affecting the subsequent biological treatment of herbal waste.					
36940872	2	37	theme	cavitation	333:342	arg1	number					344:349	the cavitation number	329:349	the cavitation number of 0.11	329:357	The HC was performed at an optimal inlet pressure equal to 3.5 bar and with the cavitation number of 0.11; the number of recirculation passes through the cavitation zone amounted to 30.5.					
36940872	0	38	theme	herbal	16:21	arg1	waste					23:27	herbal waste	16:27	herbal waste	16:27	Pretreatment of herbal waste using sonication.					
36940872	4	39	from	changes	718:724	arg1	structure					760:768	the chemical and morphological structure	729:768	the chemical and morphological structure of herbal waste	729:784	Fiber component analysis, FT-IR/ATR, TGA and SEM analysis were conducted to check the findings and to demonstrate changes in the chemical and morphological structure of herbal waste.					
35149101	4	0	theme	SEM	742:744	arg1	results					731:737	The results	727:737	The results of SEM and BET measurement	727:764	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	6	1	theme	CS/PUE18	1107:1114	arg1	hydrogels					1126:1134	CS/PUE18 composite hydrogels	1107:1134	CS/PUE18 composite hydrogels	1107:1134	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	4	2	theme	BET	750:752	arg1	measurement					754:764	BET measurement	750:764	BET measurement	750:764	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	9	3	theme	antibacterial	1541:1553	arg1	properties					1577:1586	dual antibacterial and anti-inflammatory properties	1536:1586	dual antibacterial and anti-inflammatory properties	1536:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	6	4	contain	have	1136:1139	arg2	sensitivity					1144:1154	pH sensitivity	1141:1154	pH sensitivity	1141:1154	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	6	4	contain	have	1136:1139	arg1	hydrogels					1126:1134	CS/PUE18 composite hydrogels	1107:1134	CS/PUE18 composite hydrogels	1107:1134	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	9	5	theme	delivery	1607:1614	arg1	vehicles					1616:1623	potential delivery vehicles	1597:1623	potential delivery vehicles for sustained and controlled release	1597:1660	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	2	6	from	molecule	356:363	arg1	herbal					368:373	herbal	368:373	herbal	368:373	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	3	7	theme	loss	559:562	arg1	modulus					564:570	storage modulus and loss modulus	539:570	storage modulus and loss modulus of CS/PUE18 composite hydrogels	539:602	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	9	8	theme	controlled	1643:1652	arg1	release					1654:1660	sustained and controlled release	1629:1660	sustained and controlled release	1629:1660	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	8	9	theme	berberine	1354:1362	arg1	hydrate					1373:1379	berberine chloride hydrate	1354:1379	berberine chloride hydrate (BCH)	1354:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	9	theme	berberine	1354:1362	arg1	BCH					1382:1384	BCH	1382:1384	BCH	1382:1384	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	7	10	theme	composite	1176:1184	arg1	hydrogels					1186:1194	CS/PUE18 composite hydrogels	1167:1194	CS/PUE18 composite hydrogels	1167:1194	Moreover, CS/PUE18 composite hydrogels exhibited multi-functionality including injectability, thixotropy, cytocompatibility, antibacterial and anti-inflammatory properties.					
35149101	3	11	theme	hydrogels	594:602	arg1	modulus					564:570	storage modulus and loss modulus	539:570	storage modulus and loss modulus of CS/PUE18 composite hydrogels	539:602	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	5	12	theme	hydrogen	1008:1015	arg1	bonding					1017:1023	hydrogen bonding	1008:1023	hydrogen bonding with the hydroxyl groups in PUE	1008:1055	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	9	13	theme	anti-inflammatory	1559:1575	arg1	properties					1577:1586	dual antibacterial and anti-inflammatory properties	1536:1586	dual antibacterial and anti-inflammatory properties	1536:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	0	14	theme	potential	123:131	arg1	carriers					133:140	potential carriers	123:140	potential carriers for drug delivery	123:158	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	8	15	theme	resultant	1404:1412	arg1	hydrogels					1433:1441	the resultant CS/PUE18 composite hydrogels	1400:1441	the resultant CS/PUE18 composite hydrogels	1400:1441	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	16	theme	pH	1448:1449	arg1	dependence					1451:1460	pH dependence	1448:1460	pH dependence	1448:1460	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	2	17	theme	small	350:354	arg1	molecule					356:363	a self-assembly active small molecule	327:363	a self-assembly active small molecule in herbal	327:373	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	0	18	theme	drug	146:149	arg1	delivery					151:158	drug delivery	146:158	drug delivery	146:158	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	4	19	dep	intertwined	812:822	arg1	chains					799:804	macromolecular chains	784:804	macromolecular chains of CS	784:810	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	4	20	theme	hydrogels	905:913	arg1	structure					873:881	the network structure	861:881	the network structure of CS/PUE18 composite hydrogels	861:913	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	3	21	theme	measurement	515:525	arg1	result					493:498	The result	489:498	The result of rheological measurement	489:525	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	4	22	theme	PUE	843:845	arg1	nanofibers					829:838	nanofibers	829:838	nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser	829:930	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	5	23	theme	XRD	933:935	arg1	patterns					937:944	XRD patterns	933:944	XRD patterns	933:944	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	1	24	theme	chitosan	202:209	arg1	hydrogels					234:242	chitosan physical cross-linking hydrogels	202:242	chitosan physical cross-linking hydrogels (CS hydrogels)	202:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	1	24	theme	chitosan	202:209	arg1	hydrogels					248:256	CS hydrogels	245:256	CS hydrogels	245:256	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	7	25	theme	anti-inflammatory	1300:1316	arg1	properties					1318:1327	anti-inflammatory properties	1300:1327	anti-inflammatory properties	1300:1327	Moreover, CS/PUE18 composite hydrogels exhibited multi-functionality including injectability, thixotropy, cytocompatibility, antibacterial and anti-inflammatory properties.					
35149101	4	26	theme	composite	895:903	arg1	hydrogels					905:913	CS/PUE18 composite hydrogels	886:913	CS/PUE18 composite hydrogels	886:913	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	3	27	theme	composite	584:592	arg1	hydrogels					594:602	CS/PUE18 composite hydrogels	575:602	CS/PUE18 composite hydrogels	575:602	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	5	28	from	groups	1043:1048	arg1	PUE					1053:1055	PUE	1053:1055	PUE	1053:1055	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	1	29	theme	physical	211:218	arg1	hydrogels					234:242	chitosan physical cross-linking hydrogels	202:242	chitosan physical cross-linking hydrogels (CS hydrogels)	202:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	1	29	theme	physical	211:218	arg1	hydrogels					248:256	CS hydrogels	245:256	CS hydrogels	245:256	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	0	30	theme	injectable	3:12	arg1	supramolecular					14:27	An injectable supramolecular	0:27	An injectable supramolecular	0:27	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	5	31	from	groups	988:993	arg1	CS					998:999	CS	998:999	CS	998:999	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	2	32	theme	active	343:348	arg1	molecule					356:363	a self-assembly active small molecule	327:363	a self-assembly active small molecule in herbal	327:373	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	1	33	theme	cross-linking	220:232	arg1	hydrogels					234:242	chitosan physical cross-linking hydrogels	202:242	chitosan physical cross-linking hydrogels (CS hydrogels)	202:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	1	33	theme	cross-linking	220:232	arg1	hydrogels					248:256	CS hydrogels	245:256	CS hydrogels	245:256	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	8	34	theme	chloride	1364:1371	arg1	hydrate					1373:1379	berberine chloride hydrate	1354:1379	berberine chloride hydrate (BCH)	1354:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	34	theme	chloride	1364:1371	arg1	BCH					1382:1384	BCH	1382:1384	BCH	1382:1384	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	35	from	hydrogels	1433:1441	arg1	behavior					1342:1349	The release behavior	1330:1349	The release behavior of berberine chloride hydrate (BCH)	1330:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	35	from	hydrogels	1433:1441	arg1	PUE					1391:1393	PUE	1391:1393	PUE from the resultant CS/PUE18 composite hydrogels	1391:1441	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	2	36	theme	self-assembly	329:341	arg1	molecule					356:363	a self-assembly active small molecule	327:363	a self-assembly active small molecule in herbal	327:373	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	1	37	theme	hydrogels	234:242	arg1	strength					190:197	The inherent weak mechanical strength	161:197	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels)	161:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	8	38	contain	have	1443:1446	arg2	dependence					1451:1460	pH dependence	1448:1460	pH dependence	1448:1460	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	38	contain	have	1443:1446	arg1	behavior					1342:1349	The release behavior	1330:1349	The release behavior of berberine chloride hydrate (BCH)	1330:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	38	contain	have	1443:1446	arg1	PUE					1391:1393	PUE	1391:1393	PUE from the resultant CS/PUE18 composite hydrogels	1391:1441	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	4	39	dep	demonstrated	766:777	arg1	intertwined					812:822	intertwined	812:822	intertwined	812:822	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	7	40	theme	CS/PUE18	1167:1174	arg1	hydrogels					1186:1194	CS/PUE18 composite hydrogels	1167:1194	CS/PUE18 composite hydrogels	1167:1194	Moreover, CS/PUE18 composite hydrogels exhibited multi-functionality including injectability, thixotropy, cytocompatibility, antibacterial and anti-inflammatory properties.					
35149101	3	41	theme	rheological	503:513	arg1	measurement					515:525	rheological measurement	503:525	rheological measurement	503:525	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	2	42	theme	network	470:476	arg1	structure					478:486	network structure	470:486	network structure	470:486	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	4	43	theme	CS	809:810	arg1	chains					799:804	macromolecular chains	784:804	macromolecular chains of CS	784:810	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	1	44	theme	CS	245:246	arg1	hydrogels					234:242	chitosan physical cross-linking hydrogels	202:242	chitosan physical cross-linking hydrogels (CS hydrogels)	202:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	1	44	theme	CS	245:246	arg1	hydrogels					248:256	CS hydrogels	245:256	CS hydrogels	245:256	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	8	45	theme	release	1334:1340	arg1	behavior					1342:1349	The release behavior	1330:1349	The release behavior of berberine chloride hydrate (BCH)	1330:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	4	46	theme	measurement	754:764	arg1	results					731:737	The results	727:737	The results of SEM and BET measurement	727:764	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	3	47	theme	CS	713:714	arg1	hydrogels					716:724	CS hydrogels	713:724	CS hydrogels	713:724	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	8	48	theme	hydrate	1373:1379	arg1	behavior					1342:1349	The release behavior	1330:1349	The release behavior of berberine chloride hydrate (BCH)	1330:1385	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	8	48	theme	hydrate	1373:1379	arg1	PUE					1391:1393	PUE	1391:1393	PUE from the resultant CS/PUE18 composite hydrogels	1391:1441	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	9	49	theme	sustained	1629:1637	arg1	release					1654:1660	sustained and controlled release	1629:1660	sustained and controlled release	1629:1660	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	0	50	theme	chitosan	50:57	arg1	hydrogel					59:66	chitosan hydrogel	50:66	chitosan hydrogel	50:66	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	4	51	with	intertwined	812:822	arg1	nanofibers					829:838	nanofibers	829:838	nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser	829:930	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	3	52	theme	PUE	684:686	arg1	introduction					668:679	the introduction	664:679	the introduction of PUE	664:686	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	4	53	theme	network	865:871	arg1	structure					873:881	the network structure	861:881	the network structure of CS/PUE18 composite hydrogels	861:913	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	8	54	theme	composite	1423:1431	arg1	hydrogels					1433:1441	the resultant CS/PUE18 composite hydrogels	1400:1441	the resultant CS/PUE18 composite hydrogels	1400:1441	The release behavior of berberine chloride hydrate (BCH) and PUE from the resultant CS/PUE18 composite hydrogels have pH dependence.					
35149101	2	55	theme	composite	428:436	arg1	hydrogels					438:446	CS/PUE18 composite hydrogels	419:446	CS/PUE18 composite hydrogels	419:446	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	0	56	theme	antibacterial	73:85	arg1	properties					109:118	antibacterial and anti-inflammatory properties	73:118	antibacterial and anti-inflammatory properties as potential carriers for drug delivery	73:158	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	9	57	with	hydrogels	1521:1529	arg1	properties					1577:1586	dual antibacterial and anti-inflammatory properties	1536:1586	dual antibacterial and anti-inflammatory properties	1536:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	1	58	from	applications	272:283	arg1	biomaterials					288:299	biomaterials	288:299	biomaterials	288:299	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	3	59	theme	storage	539:545	arg1	modulus					547:553	storage modulus	539:553	storage modulus	539:553	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	9	60	theme	injectable	1491:1500	arg1	hydrogels					1521:1529	injectable CS/PUE18 composite hydrogels	1491:1529	injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties	1491:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	3	61	theme	magnitude	637:645	arg1	orders					627:632	three orders	621:632	three orders of magnitude	621:645	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	3	62	theme	modulus	547:553	arg1	modulus					564:570	storage modulus and loss modulus	539:570	storage modulus and loss modulus of CS/PUE18 composite hydrogels	539:602	The result of rheological measurement showed that storage modulus and loss modulus of CS/PUE18 composite hydrogels were improved by three orders of magnitude, indicating that the introduction of PUE significantly reinforced CS hydrogels.					
35149101	9	63	theme	CS/PUE18	1502:1509	arg1	hydrogels					1521:1529	injectable CS/PUE18 composite hydrogels	1491:1529	injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties	1491:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	1	64	theme	weak	174:177	arg1	strength					190:197	The inherent weak mechanical strength	161:197	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels)	161:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	6	65	theme	swelling	1074:1081	arg1	experiments					1083:1093	Degradation and swelling experiments	1058:1093	Degradation and swelling experiments	1058:1093	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	4	66	theme	macromolecular	784:797	arg1	chains					799:804	macromolecular chains	784:804	macromolecular chains of CS	784:810	The results of SEM and BET measurement demonstrated that macromolecular chains of CS intertwined with nanofibers of PUE, which caused the network structure of CS/PUE18 composite hydrogels to become denser.					
35149101	9	67	theme	composite	1511:1519	arg1	hydrogels					1521:1529	injectable CS/PUE18 composite hydrogels	1491:1529	injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties	1491:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	5	68	theme	hydroxyl	1034:1041	arg1	groups					1043:1048	the hydroxyl groups	1030:1048	the hydroxyl groups in PUE	1030:1055	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	1	69	theme	inherent	165:172	arg1	strength					190:197	The inherent weak mechanical strength	161:197	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels)	161:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	5	70	theme	amino	982:986	arg1	groups					988:993	the amino groups	978:993	the amino groups in CS	978:999	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	0	71	theme	anti-inflammatory	91:107	arg1	properties					109:118	antibacterial and anti-inflammatory properties	73:118	antibacterial and anti-inflammatory properties as potential carriers for drug delivery	73:158	An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.					
35149101	5	72	theme	FT-IR	950:954	arg1	spectra					956:962	FT-IR spectra	950:962	FT-IR spectra	950:962	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	6	73	theme	composite	1116:1124	arg1	hydrogels					1126:1134	CS/PUE18 composite hydrogels	1107:1134	CS/PUE18 composite hydrogels	1107:1134	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	2	74	theme	CS	393:394	arg1	hydrogels					396:404	CS hydrogels	393:404	CS hydrogels	393:404	Hence, puerarin (PUE) as a self-assembly active small molecule in herbal was introduced in CS hydrogels to fabricate CS/PUE18 composite hydrogels with interpenetrating network structure.					
35149101	6	75	theme	pH	1141:1142	arg1	sensitivity					1144:1154	pH sensitivity	1141:1154	pH sensitivity	1141:1154	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
35149101	5	76	with	bonding	1017:1023	arg1	groups					1043:1048	the hydroxyl groups	1030:1048	the hydroxyl groups in PUE	1030:1055	XRD patterns and FT-IR spectra verified that the amino groups in CS formed hydrogen bonding with the hydroxyl groups in PUE.					
35149101	9	77	theme	potential	1597:1605	arg1	vehicles					1616:1623	potential delivery vehicles	1597:1623	potential delivery vehicles for sustained and controlled release	1597:1660	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	9	78	theme	dual	1536:1539	arg1	properties					1577:1586	dual antibacterial and anti-inflammatory properties	1536:1586	dual antibacterial and anti-inflammatory properties	1536:1586	These results revealed that injectable CS/PUE18 composite hydrogels with dual antibacterial and anti-inflammatory properties could be potential delivery vehicles for sustained and controlled release.					
35149101	1	79	theme	mechanical	179:188	arg1	strength					190:197	The inherent weak mechanical strength	161:197	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels)	161:257	The inherent weak mechanical strength of chitosan physical cross-linking hydrogels (CS hydrogels) limits their applications in biomaterials.					
35149101	6	80	theme	Degradation	1058:1068	arg1	experiments					1083:1093	Degradation and swelling experiments	1058:1093	Degradation and swelling experiments	1058:1093	Degradation and swelling experiments showed that CS/PUE18 composite hydrogels have pH sensitivity.					
36526062	8	0	theme	gel	1042:1044	arg1	41.7 °C					1059:1065	41.7 °C	1059:1065	41.7 °C	1059:1065	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	8	0	theme	gel	1042:1044	arg1	temperature					1046:1056	a high gel temperature	1035:1056	a high gel temperature (41.7 °C)	1035:1066	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	6	1	theme	time	815:818	arg1	temperature					798:808	temperature	798:808	temperature	798:808	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	1	theme	time	815:818	arg1	time					815:818	time	815:818	time	815:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	1	theme	time	815:818	arg1	agent					791:795	[AA]Cl agent	784:795	[AA]Cl agent	784:795	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	1	theme	time	815:818	arg1	amounts					773:779	amounts	773:779	amounts of [AA]Cl agent, temperature, and time	773:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	1	2	theme	water	170:174	arg1	solubility					176:185	good water solubility	165:185	good water solubility	165:185	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	1	3	theme	derivatizing	251:262	arg1	agent					264:268	a promising derivatizing agent	239:268	a promising derivatizing agent for cellulose	239:282	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	8	4	theme	high	1037:1040	arg1	41.7 °C					1059:1065	41.7 °C	1059:1065	41.7 °C	1059:1065	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	8	4	theme	high	1037:1040	arg1	temperature					1046:1056	a high gel temperature	1035:1056	a high gel temperature (41.7 °C)	1035:1066	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	8	5	theme	dope	961:964	arg1	test					949:952	The rheological test	933:952	The rheological test of the dope	933:964	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	7	6	theme	7 wt	888:891	arg1	aq.					899:901	7 wt% NaOH aq.	888:901	7 wt% NaOH aq.	888:901	The CAE can be well dissolved in 7 wt% NaOH aq., resulting in a 7.5 wt% dope.					
36526062	0	7	theme	acid	113:116	arg1	hydrochlorides					118:131	amino acid hydrochlorides	107:131	amino acid hydrochlorides	107:131	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	7	8	theme	%	892:892	arg1	aq.					899:901	7 wt% NaOH aq.	888:901	7 wt% NaOH aq.	888:901	The CAE can be well dissolved in 7 wt% NaOH aq., resulting in a 7.5 wt% dope.					
36526062	6	9	theme	amounts	773:779	arg1	effects					762:768	the effects	758:768	the effects of amounts of [AA]Cl agent, temperature, and time on the esterification	758:840	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	8	10	theme	rheological	937:947	arg1	test					949:952	The rheological test	933:952	The rheological test of the dope	933:964	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	0	11	theme	amino	107:111	arg1	hydrochlorides					118:131	amino acid hydrochlorides	107:131	amino acid hydrochlorides	107:131	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	3	12	theme	cellulose	474:482	arg1	CAE					502:504	CAE	502:504	CAE	502:504	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	12	theme	cellulose	474:482	arg1	ester					495:499	cellulose amino acid ester	474:499	cellulose amino acid ester (CAE)	474:505	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	13	theme	amino	484:488	arg1	CAE					502:504	CAE	502:504	CAE	502:504	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	13	theme	amino	484:488	arg1	ester					495:499	cellulose amino acid ester	474:499	cellulose amino acid ester (CAE)	474:505	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	5	14	with	CAE	644:646	arg1	degree					657:662	the degree	653:662	the degree of substitution 0.412-0.516	653:690	CAE with the degree of substitution 0.412-0.516 is facilely synthesized under 130-170 °C for 10-50 min.					
36526062	4	15	theme	reaction	567:574	arg1	rate					576:579	a significantly faster reaction rate	544:579	a significantly faster reaction rate of [AA]Cl compared to raw amino acid	544:616	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	4	16	theme	faster	560:565	arg1	rate					576:579	a significantly faster reaction rate	544:579	a significantly faster reaction rate of [AA]Cl compared to raw amino acid	544:616	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	9	17	theme	synthesized	1082:1092	arg1	products					1094:1101	the synthesized products	1078:1101	the synthesized products	1078:1101	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	6	18	from	effects	762:768	arg1	esterification					827:840	the esterification	823:840	the esterification	823:840	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	3	19	theme	amino	398:402	arg1	material					451:458	raw material	447:458	raw material	447:458	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	19	theme	amino	398:402	arg1	[AA					424:426	[AA	424:426	[AA	424:426	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	19	theme	amino	398:402	arg1	hydrochloride					409:421	amino acid hydrochloride	398:421	amino acid hydrochloride ([AA]Cl)	398:430	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	1	20	contain	have	160:163	arg2	solubility					176:185	good water solubility	165:185	good water solubility	165:185	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	1	20	contain	have	160:163	arg1	molecules					150:158	Most amino acid molecules	134:158	Most amino acid molecules	134:158	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	3	21	dep	[AA	424:426	arg1	Cl					428:429	Cl	428:429	Cl	428:429	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	22	theme	acid	404:407	arg1	material					451:458	raw material	447:458	raw material	447:458	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	22	theme	acid	404:407	arg1	[AA					424:426	[AA	424:426	[AA	424:426	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	22	theme	acid	404:407	arg1	hydrochloride					409:421	amino acid hydrochloride	398:421	amino acid hydrochloride ([AA]Cl)	398:430	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	6	23	theme	[AA	784:786	arg1	agent					791:795	[AA]Cl agent	784:795	[AA]Cl agent	784:795	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	2	24	theme	acids	321:325	arg1	efficiency					344:353	low reaction efficiency	331:353	low reaction efficiency	331:353	However, self-condensation of amino acids and low reaction efficiency always happen during esterification.					
36526062	2	24	theme	acids	321:325	arg1	self-condensation					294:310	self-condensation	294:310	self-condensation of amino acids	294:325	However, self-condensation of amino acids and low reaction efficiency always happen during esterification.					
36526062	4	25	theme	coupling	523:530	arg1	technology					532:541	TG-MS coupling technology	517:541	TG-MS coupling technology	517:541	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	9	26	theme	distinct	1108:1115	arg1	activity					1131:1138	distinct antibacterial activity	1108:1138	distinct antibacterial activity	1108:1138	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	2	27	theme	amino	315:319	arg1	acids					321:325	amino acids	315:325	amino acids	315:325	However, self-condensation of amino acids and low reaction efficiency always happen during esterification.					
36526062	1	28	theme	functional	203:212	arg1	groups					214:219	functional groups	203:219	functional groups	203:219	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	0	29	theme	solubility	14:23	arg1	activity					43:50	the solubility and antimicrobial activity	10:50	the solubility and antimicrobial activity of cellulose	10:63	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	9	30	theme	antibacterial	1117:1129	arg1	activity					1131:1138	distinct antibacterial activity	1108:1138	distinct antibacterial activity	1108:1138	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	3	31	theme	acid	490:493	arg1	CAE					502:504	CAE	502:504	CAE	502:504	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	31	theme	acid	490:493	arg1	ester					495:499	cellulose amino acid ester	474:499	cellulose amino acid ester (CAE)	474:505	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	4	32	theme	amino	607:611	arg1	acid					613:616	raw amino acid	603:616	raw amino acid	603:616	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	0	33	theme	antimicrobial	29:41	arg1	activity					43:50	the solubility and antimicrobial activity	10:50	the solubility and antimicrobial activity of cellulose	10:63	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	5	34	theme	substitution	667:678	arg1	degree					657:662	the degree	653:662	the degree of substitution 0.412-0.516	653:690	CAE with the degree of substitution 0.412-0.516 is facilely synthesized under 130-170 °C for 10-50 min.					
36526062	6	35	theme	temperature	798:808	arg1	temperature					798:808	temperature	798:808	temperature	798:808	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	35	theme	temperature	798:808	arg1	time					815:818	time	815:818	time	815:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	35	theme	temperature	798:808	arg1	agent					791:795	[AA]Cl agent	784:795	[AA]Cl agent	784:795	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	35	theme	temperature	798:808	arg1	amounts					773:779	amounts	773:779	amounts of [AA]Cl agent, temperature, and time	773:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	7	36	theme	7.5 wt	919:924	arg1	dope					927:930	a 7.5 wt% dope	917:930	a 7.5 wt% dope	917:930	The CAE can be well dissolved in 7 wt% NaOH aq., resulting in a 7.5 wt% dope.					
36526062	3	37	theme	raw	447:449	arg1	material					451:458	raw material	447:458	raw material	447:458	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	3	37	theme	raw	447:449	arg1	hydrochloride					409:421	amino acid hydrochloride	398:421	amino acid hydrochloride ([AA]Cl)	398:430	Here, amino acid hydrochloride ([AA]Cl) is selected as raw material to synthesize cellulose amino acid ester (CAE).					
36526062	0	38	theme	cellulose	55:63	arg1	activity					43:50	the solubility and antimicrobial activity	10:50	the solubility and antimicrobial activity of cellulose	10:63	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	8	39	theme	Newtonian-like	1009:1022	arg1	fluid					1024:1028	Newtonian-like fluid	1009:1028	Newtonian-like fluid	1009:1028	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	7	40	theme	%	925:925	arg1	dope					927:930	a 7.5 wt% dope	917:930	a 7.5 wt% dope	917:930	The CAE can be well dissolved in 7 wt% NaOH aq., resulting in a 7.5 wt% dope.					
36526062	1	41	theme	Most	134:137	arg1	molecules					150:158	Most amino acid molecules	134:158	Most amino acid molecules	134:158	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	8	42	theme	shear-thinning	981:994	arg1	behavior					996:1003	a shear-thinning behavior	979:1003	a shear-thinning behavior for Newtonian-like fluid	979:1028	The rheological test of the dope demonstrated a shear-thinning behavior for Newtonian-like fluid, and a high gel temperature (41.7 °C).					
36526062	4	43	theme	TG-MS	517:521	arg1	technology					532:541	TG-MS coupling technology	517:541	TG-MS coupling technology	517:541	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	6	44	theme	agent	791:795	arg1	temperature					798:808	temperature	798:808	temperature	798:808	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	44	theme	agent	791:795	arg1	time					815:818	time	815:818	time	815:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	44	theme	agent	791:795	arg1	agent					791:795	[AA]Cl agent	784:795	[AA]Cl agent	784:795	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	6	44	theme	agent	791:795	arg1	amounts					773:779	amounts	773:779	amounts of [AA]Cl agent, temperature, and time	773:818	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	9	45	theme	reduction	1163:1171	arg1	rate					1173:1176	the bacteriostatic reduction rate	1144:1176	the bacteriostatic reduction rate	1144:1176	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	1	46	theme	amino	139:143	arg1	molecules					150:158	Most amino acid molecules	134:158	Most amino acid molecules	134:158	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	6	47	theme	Cl	788:789	arg1	agent					791:795	[AA]Cl agent	784:795	[AA]Cl agent	784:795	Moreover, the effects of amounts of [AA]Cl agent, temperature, and time on the esterification are studied.					
36526062	1	48	from	groups	214:219	arg1	rich					195:198	rich	195:198	rich	195:198	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	1	49	theme	acid	145:148	arg1	molecules					150:158	Most amino acid molecules	134:158	Most amino acid molecules	134:158	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	1	50	from	rich	195:198	arg1	groups					214:219	functional groups	203:219	functional groups	203:219	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	2	51	theme	low	331:333	arg1	efficiency					344:353	low reaction efficiency	331:353	low reaction efficiency	331:353	However, self-condensation of amino acids and low reaction efficiency always happen during esterification.					
36526062	2	52	theme	reaction	335:342	arg1	efficiency					344:353	low reaction efficiency	331:353	low reaction efficiency	331:353	However, self-condensation of amino acids and low reaction efficiency always happen during esterification.					
36526062	0	53	theme	esterification	73:86	arg1	modification					88:99	esterification modification	73:99	esterification modification using amino acid hydrochlorides	73:131	Enhancing the solubility and antimicrobial activity of cellulose through esterification modification using amino acid hydrochlorides.					
36526062	4	54	theme	raw	603:605	arg1	acid					613:616	raw amino acid	603:616	raw amino acid	603:616	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	9	55	theme	bacteriostatic	1148:1161	arg1	rate					1173:1176	the bacteriostatic reduction rate	1144:1176	the bacteriostatic reduction rate	1144:1176	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	4	56	theme	Cl	588:589	arg1	rate					576:579	a significantly faster reaction rate	544:579	a significantly faster reaction rate of [AA]Cl compared to raw amino acid	544:616	Based on TG-MS coupling technology, a significantly faster reaction rate of [AA]Cl compared to raw amino acid can be observed visually.					
36526062	7	57	theme	NaOH	894:897	arg1	aq.					899:901	7 wt% NaOH aq.	888:901	7 wt% NaOH aq.	888:901	The CAE can be well dissolved in 7 wt% NaOH aq., resulting in a 7.5 wt% dope.					
36526062	1	58	theme	good	165:168	arg1	solubility					176:185	good water solubility	165:185	good water solubility	165:185	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36526062	9	59	dep	show	1103:1106	arg1	reach					1198:1202	reach	1198:1202	show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %	1103:1209	Further, the synthesized products show distinct antibacterial activity and the bacteriostatic reduction rate against E. coli can reach 99.5 %.					
36526062	1	60	theme	promising	241:249	arg1	agent					264:268	a promising derivatizing agent	239:268	a promising derivatizing agent for cellulose	239:282	Most amino acid molecules have good water solubility and are rich in functional groups, which makes them a promising derivatizing agent for cellulose.					
36740248	1	0	theme	oleogel	406:412	arg1	production					414:423	oleogel production	406:423	oleogel production with desired properties	406:447	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	0	1	from	Effect	62:67	arg1	Characteristics					104:118	Emulsion Characteristics	95:118	Emulsion Characteristics	95:118	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	5	2	theme	%	1020:1020	arg1	loss					1026:1029	21.02% oil loss	1015:1029	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	2	3	theme	various	548:554	arg1	concentrations					556:569	various concentrations	548:569	various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	548:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	7	4	theme	significant	1218:1228	arg1	effects					1230:1236	significant effects	1218:1236	significant effects	1218:1236	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	4	5	theme	glycerol	885:892	arg1	monostearate					894:905	glycerol monostearate	885:905	0.98% glycerol monostearate (w/w)	879:911	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	8	6	theme	OOE	1430:1432	arg1	applicability					1413:1425	the applicability	1409:1425	the applicability of OOE in different foods	1409:1451	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	5	7	theme	loss	1026:1029	arg1	firmness					974:981	5.81 N firmness	967:981	5.81 N firmness	967:981	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	7	theme	loss	1026:1029	arg1	value					1031:1035	21.02% oil loss value	1015:1035	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	7	8	theme	OOE	1253:1255	arg1	structure					1257:1265	the created OOE structure	1241:1265	the created OOE structure	1241:1265	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	1	9	theme	water	156:160	arg1	effects					140:146	the effects	136:146	the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE),	136:322	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	3	10	theme	quality	649:655	arg1	parameters					657:666	The optimum quality parameters	637:666	The optimum quality parameters of OOE	637:673	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	1	11	theme	glycerol	163:170	arg1	monostearate					172:183	glycerol monostearate	163:183	glycerol monostearate	163:183	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	12	from	effect	252:257	arg1	parameters					270:279	quality parameters	262:279	quality parameters	262:279	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	13	theme	optimum	352:358	arg1	amounts					360:366	their optimum amounts	346:366	their optimum amounts	346:366	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	8	14	theme	present	1365:1371	arg1	study					1373:1377	the present study	1361:1377	the present study	1361:1377	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	4	15	dep	%	816:816	arg1	oil					824:826	olive oil	818:826	53.5% olive oil	812:826	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	1	16	theme	quality	262:268	arg1	parameters					270:279	quality parameters	262:279	quality parameters	262:279	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	8	17	from	applicability	1413:1425	arg1	foods					1447:1451	different foods	1437:1451	different foods	1437:1451	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	5	18	theme	N	972:972	arg1	value					1005:1009	1.82 meq/O2 peroxide value	984:1009	1.82 meq/O2 peroxide value	984:1009	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	18	theme	N	972:972	arg1	firmness					974:981	5.81 N firmness	967:981	5.81 N firmness	967:981	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	18	theme	N	972:972	arg1	value					1031:1035	21.02% oil loss value	1015:1035	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	4	19	theme	optimum	777:783	arg1	composition					785:795	The optimum composition	773:795	The optimum composition	773:795	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	2	20	theme	0-2	608:610	arg1	%					611:611	0-2%	608:611	0-2%	608:611	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	2	21	theme	olive	473:477	arg1	oil					479:481	olive oil	473:481	olive oil	473:481	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	4	22	theme	%	833:833	arg1	water					835:839	43.5% water	829:839	43.5% water	829:839	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	5	23	theme	oil	1022:1024	arg1	loss					1026:1029	21.02% oil loss	1015:1029	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	24	theme	optimum	944:950	arg1	conditions					952:961	determined optimum conditions	933:961	determined optimum conditions	933:961	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	1	25	contain	have	233:236	arg1	concentrations					211:224	alginate concentrations	202:224	alginate concentrations	202:224	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	25	contain	have	233:236	arg2	effect					252:257	a significant effect	238:257	a significant effect on quality parameters	238:279	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	25	contain	have	233:236	arg1	monostearate					172:183	glycerol monostearate	163:183	glycerol monostearate	163:183	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	25	contain	have	233:236	arg1	oil					151:153	oil	151:153	oil	151:153	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	25	contain	have	233:236	arg1	carrageenan					186:196	carrageenan	186:196	carrageenan	186:196	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	25	contain	have	233:236	arg1	water					156:160	water	156:160	water	156:160	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	2	26	theme	%	620:620	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	0	27	theme	Oleogel	72:78	arg1	Composition					80:90	Oleogel Composition	72:90	Oleogel Composition	72:90	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	1	28	theme	oil	151:153	arg1	effects					140:146	the effects	136:146	the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE),	136:322	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	3	29	theme	oil	744:746	arg1	loss					748:751	minimum oil loss	736:751	minimum oil loss	736:751	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	4	30	theme	olive	818:822	arg1	oil					824:826	olive oil	818:826	53.5% olive oil	812:826	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	3	31	theme	firmness	710:717	arg1	value					719:723	optimum firmness value	702:723	optimum firmness value (5.5-7 N)	702:733	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	3	31	theme	firmness	710:717	arg1	N					732:732	5.5-7 N	726:732	5.5-7 N	726:732	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	5	32	theme	Produced	914:921	arg1	OOE					923:925	Produced OOE	914:925	Produced OOE under determined optimum conditions	914:961	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	4	33	dep	%	883:883	arg1	monostearate					894:905	glycerol monostearate	885:905	0.98% glycerol monostearate (w/w)	879:911	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	8	34	theme	different	1304:1312	arg1	formulations					1314:1325	different formulations	1304:1325	different formulations to be created with the results of the present study	1304:1377	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	2	35	theme	%	591:591	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	3	36	theme	value	766:770	arg1	terms					693:697	terms	693:697	terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value	693:770	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	2	37	theme	%	605:605	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	5	38	theme	meq/O2	989:994	arg1	peroxide					996:1003	1.82 meq/O2 peroxide	984:1003	1.82 meq/O2 peroxide value	984:1009	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	0	39	theme	Olive	16:20	arg1	Oil					22:24	Olive Oil	16:24	Olive Oil Oleogel-Based Emulsion Composition	16:59	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	2	40	from	concentrations	556:569	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	0	41	theme	Oleogel-Based	26:38	arg1	Composition					49:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	7	42	contain	have	1213:1216	arg2	effects					1230:1236	significant effects	1218:1236	significant effects	1218:1236	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	7	42	contain	have	1213:1216	arg1	formulation					1178:1188	the formulation	1174:1188	the formulation used in OOE production	1174:1211	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	1	43	theme	olive	284:288	arg1	oil					290:292	olive oil	284:292	olive oil oleogel-based emulsion (OOE)	284:321	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	5	44	contain	had	963:965	arg2	value					1005:1009	1.82 meq/O2 peroxide value	984:1009	1.82 meq/O2 peroxide value	984:1009	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	44	contain	had	963:965	arg1	OOE					923:925	Produced OOE	914:925	Produced OOE under determined optimum conditions	914:961	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	44	contain	had	963:965	arg2	firmness					974:981	5.81 N firmness	967:981	5.81 N firmness	967:981	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	44	contain	had	963:965	arg2	value					1031:1035	21.02% oil loss value	1015:1035	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	0	45	theme	Composition	49:59	arg1	Optimization					0:11	Optimization	0:11	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.	0:119	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	1	46	theme	oleogel-based	294:306	arg1	OOE					318:320	OOE	318:320	OOE	318:320	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	46	theme	oleogel-based	294:306	arg1	emulsion					308:315	olive oil oleogel-based emulsion	284:315	olive oil oleogel-based emulsion (OOE)	284:321	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	47	with	production	414:423	arg1	properties					438:447	desired properties	430:447	desired properties	430:447	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	48	theme	alginate	202:209	arg1	concentrations					211:224	alginate concentrations	202:224	alginate concentrations	202:224	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	8	49	dep	formulations	1314:1325	arg1	created					1333:1339	created	1333:1339	to be created with the results of the present study	1327:1377	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	7	50	theme	quality	1271:1277	arg1	parameters					1279:1288	quality parameters	1271:1288	quality parameters	1271:1288	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	0	51	dep	Optimization	0:11	arg1	Effect					62:67	Effect	62:67	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.	0:119	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	5	52	theme	21.02	1015:1019	arg1	%					1020:1020	%	1020:1020	%	1020:1020	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	6	53	theme	obtained	1085:1092	arg1	data					1094:1097	the experimentally obtained data	1066:1097	the experimentally obtained data	1066:1097	The margin of error between the experimentally obtained data and the estimated data in the study is average 2%.					
36740248	1	54	theme	significant	240:250	arg1	effect					252:257	a significant effect	238:257	a significant effect on quality parameters	238:279	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	7	55	theme	created	1245:1251	arg1	structure					1257:1265	the created OOE structure	1241:1265	the created OOE structure	1241:1265	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	1	56	theme	desired	430:436	arg1	properties					438:447	desired properties	430:447	desired properties	430:447	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	6	57	theme	error	1052:1056	arg1	margin					1042:1047	The margin	1038:1047	The margin of error between the experimentally obtained data and the estimated data in the study	1038:1133	The margin of error between the experimentally obtained data and the estimated data in the study is average 2%.					
36740248	7	58	theme	OOE	1198:1200	arg1	production					1202:1211	OOE production	1198:1211	OOE production	1198:1211	The results showed that the formulation used in OOE production have significant effects on the created OOE structure and quality parameters.					
36740248	1	59	theme	monostearate	172:183	arg1	effects					140:146	the effects	136:146	the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE),	136:322	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	3	60	theme	optimum	641:647	arg1	parameters					657:666	The optimum quality parameters	637:666	The optimum quality parameters of OOE	637:673	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	1	61	theme	carrageenan	186:196	arg1	effects					140:146	the effects	136:146	the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE),	136:322	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	2	62	theme	0-2	617:619	arg1	%					620:620	0-2%	617:620	0-2%	617:620	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	6	63	from	data	1117:1120	arg1	study					1129:1133	the study	1125:1133	the study	1125:1133	The margin of error between the experimentally obtained data and the estimated data in the study is average 2%.					
36740248	2	64	theme	glycerol	491:498	arg1	GMS					514:516	GMS	514:516	GMS	514:516	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	2	64	theme	glycerol	491:498	arg1	monostearate					500:511	glycerol monostearate	491:511	glycerol monostearate (GMS)	491:517	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	2	65	theme	%	611:611	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	3	66	theme	OOE	671:673	arg1	parameters					657:666	The optimum quality parameters	637:666	The optimum quality parameters of OOE	637:673	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	6	67	theme	estimated	1107:1115	arg1	data					1117:1120	the estimated data	1103:1120	the estimated data in the study	1103:1133	The margin of error between the experimentally obtained data and the estimated data in the study is average 2%.					
36740248	1	68	theme	mixture	387:393	arg1	design					395:400	mixture design	387:400	mixture design	387:400	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	3	69	theme	minimum	736:742	arg1	loss					748:751	minimum oil loss	736:751	minimum oil loss	736:751	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	3	70	theme	optimum	702:708	arg1	value					719:723	optimum firmness value	702:723	optimum firmness value (5.5-7 N)	702:733	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	3	70	theme	optimum	702:708	arg1	N					732:732	5.5-7 N	726:732	5.5-7 N	726:732	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	4	71	theme	43.5	829:832	arg1	%					833:833	%	833:833	%	833:833	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	0	72	theme	Composition	80:90	arg1	Effect					62:67	Effect	62:67	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.	0:119	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	3	73	theme	peroxide	757:764	arg1	value					766:770	peroxide value	757:770	peroxide value	757:770	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	2	74	theme	%	599:599	arg1	range					578:582	the range	574:582	the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively	574:634	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	0	75	theme	Emulsion	95:102	arg1	Characteristics					104:118	Emulsion Characteristics	95:118	Emulsion Characteristics	95:118	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	5	76	theme	5.81	967:970	arg1	value					1005:1009	1.82 meq/O2 peroxide value	984:1009	1.82 meq/O2 peroxide value	984:1009	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	76	theme	5.81	967:970	arg1	firmness					974:981	5.81 N firmness	967:981	5.81 N firmness	967:981	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	76	theme	5.81	967:970	arg1	value					1031:1035	21.02% oil loss value	1015:1035	21.02% oil loss value	1015:1035	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	3	77	theme	loss	748:751	arg1	terms					693:697	terms	693:697	terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value	693:770	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	3	78	theme	value	719:723	arg1	terms					693:697	terms	693:697	terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value	693:770	The optimum quality parameters of OOE were evaluated in terms of optimum firmness value (5.5-7 N), minimum oil loss and peroxide value.					
36740248	5	79	theme	determined	933:942	arg1	conditions					952:961	determined optimum conditions	933:961	determined optimum conditions	933:961	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	2	80	theme	0-2	602:604	arg1	%					605:605	0-2%	602:605	0-2%	602:605	OOE was produced using olive oil, water, glycerol monostearate (GMS), carrageenan and alginate at various concentrations in the range of 0-70%, 30-60%, 0-2%, 0-2% and 0-2%, respectively.					
36740248	0	81	theme	Oil	22:24	arg1	Composition					49:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	5	82	theme	peroxide	996:1003	arg1	value					1005:1009	1.82 meq/O2 peroxide value	984:1009	1.82 meq/O2 peroxide value	984:1009	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	5	82	theme	peroxide	996:1003	arg1	firmness					974:981	5.81 N firmness	967:981	5.81 N firmness	967:981	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	4	83	theme	alginate	866:873	arg1	%					864:864	0.92% alginate	860:873	0.92% alginate	860:873	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	0	84	theme	Emulsion	40:47	arg1	Composition					49:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Olive Oil Oleogel-Based Emulsion Composition	16:59	Optimization of Olive Oil Oleogel-Based Emulsion Composition: Effect of Oleogel Composition on Emulsion Characteristics.					
36740248	1	85	theme	oil	290:292	arg1	OOE					318:320	OOE	318:320	OOE	318:320	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	1	85	theme	oil	290:292	arg1	emulsion					308:315	olive oil oleogel-based emulsion	284:315	olive oil oleogel-based emulsion (OOE)	284:321	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	4	86	theme	carrageenan	847:857	arg1	%					845:845	1.1% carrageenan	842:857	1.1% carrageenan	842:857	The optimum composition was determined 53.5% olive oil, 43.5% water, 1.1% carrageenan, 0.92% alginate and 0.98% glycerol monostearate (w/w).					
36740248	8	87	theme	study	1373:1377	arg1	results					1350:1356	the results	1346:1356	the results of the present study	1346:1377	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	8	88	theme	different	1437:1445	arg1	foods					1447:1451	different foods	1437:1451	different foods	1437:1451	In addition, different formulations to be created with the results of the present study will contribute to increasing the applicability of OOE in different foods.					
36740248	5	89	theme	1.82	984:987	arg1	meq/O2					989:994	meq/O2	989:994	meq/O2	989:994	Produced OOE under determined optimum conditions had 5.81 N firmness, 1.82 meq/O2 peroxide value and 21.02% oil loss value.					
36740248	1	90	theme	concentrations	211:224	arg1	effects					140:146	the effects	136:146	the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE),	136:322	In this study, the effects of oil, water, glycerol monostearate, carrageenan and alginate concentrations, which have a significant effect on quality parameters in olive oil oleogel-based emulsion (OOE), were investigated and their optimum amounts were determined by mixture design for oleogel production with desired properties.					
36740248	6	91	from	data	1094:1097	arg1	study					1129:1133	the study	1125:1133	the study	1125:1133	The margin of error between the experimentally obtained data and the estimated data in the study is average 2%.					
36395950	5	0	theme	antioxidant	1002:1012	arg1	activities					1014:1023	its excellent antioxidant activities	988:1023	its excellent antioxidant activities	988:1023	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	1	1	theme	active	156:161	arg1	film					187:190	a novel active chitosan (CH) packaging film	148:190	a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC)	148:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	2	2	theme	contact	438:444	arg1	angle					446:450	its water contact angle	428:450	its water contact angle	428:450	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	3	3	theme	lower	636:640	arg1	layer					642:646	the lower layer	632:646	the lower layer	632:646	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	4	4	theme	%	787:787	arg1	CNC					789:791	0.8 % CNC	783:791	0.8 % CNC	783:791	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	4	4	theme	%	787:787	arg1	composition					738:748	The optimal composition	726:748	The optimal composition of the film	726:760	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	1	5	theme	chitosan	163:170	arg1	film					187:190	a novel active chitosan (CH) packaging film	148:190	a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC)	148:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	0	6	theme	electrostatic	109:121	arg1	spraying					123:130	electrostatic spraying	109:130	electrostatic spraying	109:130	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	4	7	theme	4 	797:798	arg1	%					799:799	%	799:799	%	799:799	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	1	8	theme	stem	239:242	arg1	CNC					268:270	CNC	268:270	CNC	268:270	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	1	8	theme	stem	239:242	arg1	nanocrystals					254:265	stem cellulose nanocrystals	239:265	stem cellulose nanocrystals (CNC)	239:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	2	9	theme	antibacterial	536:548	arg1	activities					550:559	its antioxidant and antibacterial activities	516:559	its antioxidant and antibacterial activities	516:559	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	2	10	theme	CH	314:315	arg1	film					317:320	the CH film	310:320	the CH film	310:320	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	1	11	theme	cellulose	244:252	arg1	CNC					268:270	CNC	268:270	CNC	268:270	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	1	11	theme	cellulose	244:252	arg1	nanocrystals					254:265	stem cellulose nanocrystals	239:265	stem cellulose nanocrystals (CNC)	239:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	4	12	theme	fuzzy	811:815	arg1	method					840:845	the fuzzy mathematics evaluation method	807:845	the fuzzy mathematics evaluation method	807:845	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	3	13	from	agglomerates	603:614	arg1	layer					642:646	the lower layer	632:646	the lower layer	632:646	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	14	theme	surface	656:662	arg1	CNC					599:601	the CNC agglomerates and deposits in the lower layer and the surface roughness of the film	595:684	CNC	599:601	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	14	theme	surface	656:662	arg1	roughness					664:672	the surface roughness	652:672	the surface roughness of the film	652:684	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	14	theme	surface	656:662	arg1	highest					694:700	highest	694:700	highest	694:700	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	0	15	theme	nanocrystal/leaf	37:52	arg1	Preparation					0:10	Preparation	0:10	Preparation of garlic stem cellulose nanocrystal/leaf	0:52	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	1	16	theme	CH	173:174	arg1	film					187:190	a novel active chitosan (CH) packaging film	148:190	a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC)	148:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	0	17	theme	garlic	86:91	arg1	preservation					93:104	black garlic preservation	80:104	black garlic preservation	80:104	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	4	18	theme	0.8 	783:786	arg1	%					787:787	%	787:787	%	787:787	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	2	19	theme	weight-loss	456:466	arg1	rate					468:471	weight-loss rate	456:471	weight-loss rate	456:471	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	4	20	theme	%	799:799	arg1	GL					801:802	4 % GL	797:802	4 % GL	797:802	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	2	21	theme	tensile	336:342	arg1	strength					344:351	its tensile strength	332:351	its tensile strength	332:351	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	2	22	theme	water/oxygen	393:404	arg1	barrier					406:412	water/oxygen barrier	393:412	water/oxygen barrier	393:412	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	1	23	theme	packaging	177:185	arg1	film					187:190	a novel active chitosan (CH) packaging film	148:190	a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC)	148:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	0	24	theme	stem	22:25	arg1	nanocrystal/leaf					37:52	garlic stem cellulose nanocrystal/leaf	15:52	garlic stem cellulose nanocrystal/leaf	15:52	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	5	25	theme	storage	1073:1079	arg1	90 d					1065:1068	90 d	1065:1068	90 d of storage	1065:1079	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	4	26	theme	mathematics	817:827	arg1	method					840:845	the fuzzy mathematics evaluation method	807:845	the fuzzy mathematics evaluation method	807:845	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	5	27	theme	electrostatic	911:923	arg1	spraying					925:932	electrostatic spraying	911:932	electrostatic spraying	911:932	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	0	28	theme	garlic	15:20	arg1	nanocrystal/leaf					37:52	garlic stem cellulose nanocrystal/leaf	15:52	garlic stem cellulose nanocrystal/leaf	15:52	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	3	29	theme	film	681:684	arg1	CNC					599:601	the CNC agglomerates and deposits in the lower layer and the surface roughness of the film	595:684	CNC	599:601	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	29	theme	film	681:684	arg1	roughness					664:672	the surface roughness	652:672	the surface roughness of the film	652:684	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	29	theme	film	681:684	arg1	highest					694:700	highest	694:700	highest	694:700	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	2	30	theme	GL	496:497	arg1	addition					484:491	the addition	480:491	the addition of GL	480:497	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	5	31	theme	black	854:858	arg1	garlic					860:865	black garlic	854:865	black garlic	854:865	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	2	32	theme	thermal	370:376	arg1	stability					378:386	thermal stability	370:386	thermal stability	370:386	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	2	33	theme	water	432:436	arg1	angle					446:450	its water contact angle	428:450	its water contact angle	428:450	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	4	34	theme	optimal	730:736	arg1	CNC					789:791	0.8 % CNC	783:791	0.8 % CNC	783:791	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	4	34	theme	optimal	730:736	arg1	composition					738:748	The optimal composition	726:748	The optimal composition of the film	726:760	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	0	35	theme	cellulose	27:35	arg1	nanocrystal/leaf					37:52	garlic stem cellulose nanocrystal/leaf	15:52	garlic stem cellulose nanocrystal/leaf	15:52	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	3	36	theme	%	709:709	arg1	concentration					711:723	1.2 % concentration	705:723	1.2 % concentration	705:723	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	4	37	theme	evaluation	829:838	arg1	method					840:845	the fuzzy mathematics evaluation method	807:845	the fuzzy mathematics evaluation method	807:845	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	3	38	theme	SEM	562:564	arg1	analyses					574:581	SEM and AFM analyses	562:581	SEM and AFM analyses	562:581	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	1	39	theme	garlic	210:215	arg1	GL					231:232	GL	231:232	GL	231:232	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	1	39	theme	garlic	210:215	arg1	extract					222:228	garlic leaf extract	210:228	garlic leaf extract (GL)	210:233	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	5	40	theme	browning	1049:1056	arg1	degree					1039:1044	the degree	1035:1044	the degree of browning	1035:1056	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	5	41	theme	excellent	992:1000	arg1	activities					1014:1023	its excellent antioxidant activities	988:1023	its excellent antioxidant activities	988:1023	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	2	42	theme	antioxidant	520:530	arg1	activities					550:559	its antioxidant and antibacterial activities	516:559	its antioxidant and antibacterial activities	516:559	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	4	43	theme	film	757:760	arg1	CNC					789:791	0.8 % CNC	783:791	0.8 % CNC	783:791	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	4	43	theme	film	757:760	arg1	composition					738:748	The optimal composition	726:748	The optimal composition of the film	726:760	The optimal composition of the film was determined to be 0.8 % CNC and 4 % GL by the fuzzy mathematics evaluation method.					
36395950	2	44	theme	CNC	303:305	arg1	addition					291:298	The addition	287:298	The addition of CNC to the CH film	287:320	The addition of CNC to the CH film increased its tensile strength, hydrophilicity, thermal stability, and water/oxygen barrier and decreased its water contact angle and weight-loss rate, while the addition of GL greatly enhanced its antioxidant and antibacterial activities.					
36395950	3	45	theme	1.2 	705:708	arg1	%					709:709	%	709:709	%	709:709	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	1	46	theme	leaf	217:220	arg1	GL					231:232	GL	231:232	GL	231:232	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	1	46	theme	leaf	217:220	arg1	extract					222:228	garlic leaf extract	210:228	garlic leaf extract (GL)	210:233	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
36395950	5	47	theme	slow	951:954	arg1	loss					962:965	slow water loss	951:965	slow water loss	951:965	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	5	48	theme	optimized	890:898	arg1	coating					900:906	the optimized coating	886:906	the optimized coating by electrostatic spraying	886:932	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	0	49	theme	black	80:84	arg1	preservation					93:104	black garlic preservation	80:104	black garlic preservation	80:104	Preparation of garlic stem cellulose nanocrystal/leaf extract/chitosan film for black garlic preservation by electrostatic spraying.					
36395950	5	50	theme	water	956:960	arg1	loss					962:965	slow water loss	951:965	slow water loss	951:965	Then, black garlic was preserved with the optimized coating by electrostatic spraying and was found to slow water loss and migration, while its excellent antioxidant activities decreased the degree of browning during 90 d of storage.					
36395950	3	51	dep	CNC	599:601	arg1	deposits					620:627	deposits	620:627	deposits	620:627	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	51	dep	CNC	599:601	arg1	agglomerates					603:614	agglomerates	603:614	agglomerates	603:614	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	52	from	deposits	620:627	arg1	layer					642:646	the lower layer	632:646	the lower layer	632:646	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	3	53	theme	AFM	570:572	arg1	analyses					574:581	SEM and AFM analyses	562:581	SEM and AFM analyses	562:581	SEM and AFM analyses showed that the CNC agglomerates and deposits in the lower layer and the surface roughness of the film was the highest at 1.2 % concentration.					
36395950	1	54	theme	novel	150:154	arg1	film					187:190	a novel active chitosan (CH) packaging film	148:190	a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC)	148:271	In this study, a novel active chitosan (CH) packaging film that incorporates garlic leaf extract (GL) and stem cellulose nanocrystals (CNC) was prepared.					
35030225	5	0	dep	protein	648:654	arg1	release					673:679	release	673:679	release	673:679	Here, we evaluate different common methods to break up the algal cell wall effectively and measure the success by protein and carbohydrate release.					
35030225	10	1	theme	strong	1490:1495	arg1	extracts					1504:1511	strong alkali extracts	1490:1511	strong alkali extracts	1490:1511	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	5	2	theme	cell	599:602	arg1	wall					604:607	the algal cell wall	589:607	the algal cell wall	589:607	Here, we evaluate different common methods to break up the algal cell wall effectively and measure the success by protein and carbohydrate release.					
35030225	7	3	theme	alkali	853:858	arg1	hydrolysis					870:879	alkali catalyzed hydrolysis	853:879	alkali catalyzed hydrolysis of the Chlorella vulgaris cells	853:911	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	9	4	theme	cell	1379:1382	arg1	wall					1384:1387	the cell wall	1375:1387	the cell wall	1375:1387	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	7	5	theme	total	1016:1020	arg1	biomass					1022:1028	the total biomass	1012:1028	the total biomass	1012:1028	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	5	6	theme	different	552:560	arg1	methods					569:575	different common methods	552:575	different common methods	552:575	Here, we evaluate different common methods to break up the algal cell wall effectively and measure the success by protein and carbohydrate release.					
35030225	7	7	theme	chemical	830:837	arg1	technologies					839:850	different mechanical and chemical technologies	805:850	different mechanical and chemical technologies	805:850	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	1	8	theme	other	226:230	arg1	compounds					241:249	other valuable compounds	226:249	other valuable compounds	226:249	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	12	9	theme	cell	1702:1705	arg1	walls					1707:1711	Chlorella cell walls	1692:1711	Chlorella cell walls	1692:1711	Our results might help to tailor more specific efforts to disrupt Chlorella cell walls and help to valorize microalgae biomass.					
35030225	5	10	theme	common	562:567	arg1	methods					569:575	different common methods	552:575	different common methods	552:575	Here, we evaluate different common methods to break up the algal cell wall effectively and measure the success by protein and carbohydrate release.					
35030225	1	11	theme	valuable	232:239	arg1	compounds					241:249	other valuable compounds	226:249	other valuable compounds	226:249	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	4	12	theme	wall	446:449	arg1	structures					451:460	The wall structures	442:460	The wall structures that are responsible for this robustness	442:501	The wall structures that are responsible for this robustness have been studied less so far.					
35030225	4	12	theme	wall	446:449	arg1	responsible					471:481	responsible	471:481	responsible	471:481	The wall structures that are responsible for this robustness have been studied less so far.					
35030225	10	13	theme	polymers	1443:1450	arg1	presence					1409:1416	the presence	1405:1416	the presence of chitin or chitin-like polymers	1405:1450	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	7	14	theme	mechanical	815:824	arg1	technologies					839:850	different mechanical and chemical technologies	805:850	different mechanical and chemical technologies	805:850	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	1	15	theme	compounds	241:249	arg1	production					199:208	the production	195:208	the production of proteins and other valuable compounds	195:249	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	11	16	theme	strong	1602:1607	arg1	extracts					1616:1623	strong acidic extracts	1602:1623	strong acidic extracts	1602:1623	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	9	17	theme	composition	1273:1283	arg1	analysis					1242:1249	A detailed analysis	1231:1249	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step	1231:1323	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	10	18	theme	chitin	1421:1426	arg1	polymers					1443:1450	chitin or chitin-like polymers	1421:1450	chitin or chitin-like polymers	1421:1450	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	12	19	theme	Chlorella	1692:1700	arg1	walls					1707:1711	Chlorella cell walls	1692:1711	Chlorella cell walls	1692:1711	Our results might help to tailor more specific efforts to disrupt Chlorella cell walls and help to valorize microalgae biomass.					
35030225	9	20	theme	wall	1384:1387	arg1	robustness					1361:1370	the robustness	1357:1370	the robustness of the cell wall	1357:1387	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	2	21	theme	cell	362:365	arg1	wall					367:370	the recalcitrant microalgal cell wall	334:370	the recalcitrant microalgal cell wall	334:370	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	0	22	theme	Chlorella	42:50	arg1	vulgaris					52:59	Chlorella vulgaris	42:59	Chlorella vulgaris	42:59	Insights into cell wall disintegration of Chlorella vulgaris.					
35030225	11	23	theme	acidic	1609:1614	arg1	extracts					1616:1623	strong acidic extracts	1602:1623	strong acidic extracts	1602:1623	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	7	24	theme	cells	907:911	arg1	hydrolysis					870:879	alkali catalyzed hydrolysis	853:879	alkali catalyzed hydrolysis of the Chlorella vulgaris cells	853:911	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	7	25	dep	%	974:974	arg1	wt					972:973	wt	972:973	wt	972:973	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	2	26	theme	wall	367:370	arg1	disruption					320:329	the effective disruption	306:329	the effective disruption of the recalcitrant microalgal cell wall	306:370	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	8	27	theme	strong	1128:1133	arg1	conditions					1135:1144	increasingly strong conditions	1115:1144	increasingly strong conditions	1115:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	7	28	theme	biomass	1022:1028	arg1	carbohydrates					995:1007	14 wt% carbohydrates	988:1007	14 wt% carbohydrates of the total biomass	988:1028	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	7	28	theme	biomass	1022:1028	arg1	protein					976:982	up to 56 wt% protein	963:982	up to 56 wt% protein	963:982	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	8	29	with	chemicals	1100:1108	arg1	conditions					1135:1144	increasingly strong conditions	1115:1144	increasingly strong conditions	1115:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	2	30	theme	biomass	287:293	arg1	valorization					265:276	the valorization	261:276	the valorization of algal biomass	261:293	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	7	31	theme	different	805:813	arg1	technologies					839:850	different mechanical and chemical technologies	805:850	different mechanical and chemical technologies	805:850	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	3	32	theme	Chlorella	398:406	arg1	species					408:414	Chlorella species	398:414	Chlorella species	398:414	Especially cell walls of Chlorella species proved to be very robust.					
35030225	10	33	theme	chitin-like	1431:1441	arg1	polymers					1443:1450	chitin or chitin-like polymers	1421:1450	chitin or chitin-like polymers	1421:1450	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	9	34	theme	cell	1292:1295	arg1	wall					1297:1300	the cell wall	1288:1300	the cell wall extracted in each step	1288:1323	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	5	35	theme	algal	593:597	arg1	wall					604:607	the algal cell wall	589:607	the algal cell wall	589:607	Here, we evaluate different common methods to break up the algal cell wall effectively and measure the success by protein and carbohydrate release.					
35030225	7	36	theme	Chlorella	888:896	arg1	cells					907:911	the Chlorella vulgaris cells	884:911	the Chlorella vulgaris cells	884:911	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	2	37	theme	algal	281:285	arg1	biomass					287:293	algal biomass	281:293	algal biomass	281:293	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	3	38	theme	species	408:414	arg1	walls					389:393	Especially cell walls	373:393	Especially cell walls of Chlorella species	373:414	Especially cell walls of Chlorella species proved to be very robust.					
35030225	0	39	theme	wall	19:22	arg1	disintegration					24:37	cell wall disintegration	14:37	cell wall disintegration of Chlorella vulgaris	14:59	Insights into cell wall disintegration of Chlorella vulgaris.					
35030225	9	40	theme	wall	1297:1300	arg1	composition					1273:1283	the monosaccharide composition	1254:1283	the monosaccharide composition of the cell wall extracted in each step	1254:1323	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	7	41	theme	vulgaris	898:905	arg1	cells					907:911	the Chlorella vulgaris cells	884:911	the Chlorella vulgaris cells	884:911	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	1	42	theme	fixation	88:95	arg1	ability					73:79	their ability	67:79	their ability of CO2 fixation using sunlight as an energy source	67:130	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	8	43	theme	carbohydrates	1216:1228	arg1	ratios					1193:1198	different ratios	1183:1198	different ratios of proteins and carbohydrates	1183:1228	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	1	44	theme	CO2	84:86	arg1	fixation					88:95	CO2 fixation	84:95	CO2 fixation	84:95	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	7	45	theme	56	969:970	arg1	wt					972:973	wt	972:973	wt	972:973	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	7	46	dep	wt	972:973	arg1	to					966:967	to	966:967	to	966:967	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	8	47	theme	stepwise	1035:1042	arg1	degradation					1044:1054	The stepwise degradation	1031:1054	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions	1031:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	11	48	located	detected	1590:1597	arg1	extracts					1616:1623	strong acidic extracts	1602:1623	strong acidic extracts	1602:1623	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	11	48	located	detected	1590:1597	arg2	glucose					1582:1588	glucose	1582:1588	glucose detected in strong acidic extracts	1582:1623	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	2	49	theme	microalgal	351:360	arg1	wall					367:370	the recalcitrant microalgal cell wall	334:370	the recalcitrant microalgal cell wall	334:370	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	9	50	theme	monosaccharide	1258:1271	arg1	composition					1273:1283	the monosaccharide composition	1254:1283	the monosaccharide composition of the cell wall extracted in each step	1254:1323	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	6	51	theme	wall	722:725	arg1	features					727:734	algal cell wall features	711:734	algal cell wall features playing a role in the wall's recalcitrance towards disruption	711:796	Subsequently, we investigate algal cell wall features playing a role in the wall's recalcitrance towards disruption.					
35030225	8	52	theme	chemicals	1100:1108	arg1	series					1090:1095	a series	1088:1095	a series of chemicals with increasingly strong conditions	1088:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	0	53	theme	vulgaris	52:59	arg1	disintegration					24:37	cell wall disintegration	14:37	cell wall disintegration of Chlorella vulgaris	14:59	Insights into cell wall disintegration of Chlorella vulgaris.					
35030225	7	54	theme	wt	991:992	arg1	carbohydrates					995:1007	14 wt% carbohydrates	988:1007	14 wt% carbohydrates of the total biomass	988:1028	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	10	55	theme	alkali	1497:1502	arg1	extracts					1504:1511	strong alkali extracts	1490:1511	strong alkali extracts	1490:1511	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	6	56	theme	cell	717:720	arg1	features					727:734	algal cell wall features	711:734	algal cell wall features playing a role in the wall's recalcitrance towards disruption	711:796	Subsequently, we investigate algal cell wall features playing a role in the wall's recalcitrance towards disruption.					
35030225	2	57	theme	effective	310:318	arg1	disruption					320:329	the effective disruption	306:329	the effective disruption of the recalcitrant microalgal cell wall	306:370	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	3	58	theme	cell	384:387	arg1	walls					389:393	Especially cell walls	373:393	Especially cell walls of Chlorella species	373:414	Especially cell walls of Chlorella species proved to be very robust.					
35030225	7	59	theme	%	993:993	arg1	carbohydrates					995:1007	14 wt% carbohydrates	988:1007	14 wt% carbohydrates of the total biomass	988:1028	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	6	60	theme	algal	711:715	arg1	features					727:734	algal cell wall features	711:734	algal cell wall features playing a role in the wall's recalcitrance towards disruption	711:796	Subsequently, we investigate algal cell wall features playing a role in the wall's recalcitrance towards disruption.					
35030225	10	61	located	found	1481:1485	arg1	extracts					1504:1511	strong alkali extracts	1490:1511	strong alkali extracts	1490:1511	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	10	61	located	found	1481:1485	arg2	glucosamine					1469:1479	glucosamine	1469:1479	glucosamine found in strong alkali extracts	1469:1511	In particular, the presence of chitin or chitin-like polymers was indicated by glucosamine found in strong alkali extracts.					
35030225	9	62	theme	possible	1336:1343	arg1	factors					1345:1351	possible factors	1336:1351	possible factors for the robustness of the cell wall	1336:1387	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	8	63	theme	vulgaris	1062:1069	arg1	walls					1076:1080	C. vulgaris cell walls	1059:1080	C. vulgaris cell walls using a series of chemicals with increasingly strong conditions	1059:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	8	64	theme	proteins	1203:1210	arg1	ratios					1193:1198	different ratios	1183:1198	different ratios of proteins and carbohydrates	1183:1228	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	8	65	theme	C.	1059:1060	arg1	walls					1076:1080	C. vulgaris cell walls	1059:1080	C. vulgaris cell walls using a series of chemicals with increasingly strong conditions	1059:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	11	66	theme	starch	1545:1550	arg1	presence					1518:1525	The presence	1514:1525	The presence of highly ordered starch or cellulose	1514:1563	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	12	67	theme	microalgae	1734:1743	arg1	biomass					1745:1751	microalgae biomass	1734:1751	microalgae biomass	1734:1751	Our results might help to tailor more specific efforts to disrupt Chlorella cell walls and help to valorize microalgae biomass.					
35030225	1	68	theme	energy	118:123	arg1	sunlight					103:110	sunlight	103:110	sunlight	103:110	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	1	68	theme	energy	118:123	arg1	source					125:130	an energy source	115:130	an energy source	115:130	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
35030225	7	69	theme	catalyzed	860:868	arg1	hydrolysis					870:879	alkali catalyzed hydrolysis	853:879	alkali catalyzed hydrolysis of the Chlorella vulgaris cells	853:911	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	8	70	theme	walls	1076:1080	arg1	degradation					1044:1054	The stepwise degradation	1031:1054	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions	1031:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	12	71	theme	specific	1664:1671	arg1	efforts					1673:1679	more specific efforts	1659:1679	more specific efforts	1659:1679	Our results might help to tailor more specific efforts to disrupt Chlorella cell walls and help to valorize microalgae biomass.					
35030225	2	72	theme	recalcitrant	338:349	arg1	wall					367:370	the recalcitrant microalgal cell wall	334:370	the recalcitrant microalgal cell wall	334:370	However, the valorization of algal biomass depends on the effective disruption of the recalcitrant microalgal cell wall.					
35030225	8	73	theme	different	1183:1191	arg1	ratios					1193:1198	different ratios	1183:1198	different ratios of proteins and carbohydrates	1183:1228	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	11	74	theme	ordered	1537:1543	arg1	starch					1545:1550	starch	1545:1550	starch	1545:1550	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	8	75	theme	cell	1071:1074	arg1	walls					1076:1080	C. vulgaris cell walls	1059:1080	C. vulgaris cell walls using a series of chemicals with increasingly strong conditions	1059:1144	The stepwise degradation of C. vulgaris cell walls using a series of chemicals with increasingly strong conditions revealed that each fraction released different ratios of proteins and carbohydrates.					
35030225	9	76	theme	detailed	1233:1240	arg1	analysis					1242:1249	A detailed analysis	1231:1249	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step	1231:1323	A detailed analysis of the monosaccharide composition of the cell wall extracted in each step identified possible factors for the robustness of the cell wall.					
35030225	0	77	theme	cell	14:17	arg1	disintegration					24:37	cell wall disintegration	14:37	cell wall disintegration of Chlorella vulgaris	14:59	Insights into cell wall disintegration of Chlorella vulgaris.					
35030225	11	78	theme	cellulose	1555:1563	arg1	presence					1518:1525	The presence	1514:1525	The presence of highly ordered starch or cellulose	1514:1563	The presence of highly ordered starch or cellulose was indicated by glucose detected in strong acidic extracts.					
35030225	7	79	dep	protein	976:982	arg1	%					974:974	%	974:974	%	974:974	Using different mechanical and chemical technologies, alkali catalyzed hydrolysis of the Chlorella vulgaris cells proved to be especially effective in solubilizing up to 56 wt% protein and 14 wt% carbohydrates of the total biomass.					
35030225	1	80	theme	proteins	213:220	arg1	production					199:208	the production	195:208	the production of proteins and other valuable compounds	195:249	With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins and other valuable compounds.					
36473529	0	0	theme	efficient	84:92	arg1	removal					107:113	highly efficient tetracycline removal	77:113	highly efficient tetracycline removal	77:113	Bimetallic MOFs loaded cellulose as an environment friendly bioadsorbent for highly efficient tetracycline removal.					
36473529	5	1	theme	Fe/ZIF-8	816:823	arg1	cellulose					825:833	Fe/ZIF-8@cellulose	816:833	Fe/ZIF-8@cellulose	816:833	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	7	2	theme	load	1070:1073	arg1	Fe/ZIF-8					1075:1082	load Fe/ZIF-8	1070:1082	load Fe/ZIF-8	1070:1082	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	5	3	theme	polysaccharide	925:938	arg1	adsorbents					946:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	5	4	theme	adsorption	793:802	arg1	capacity					804:811	the maximum adsorption capacity	781:811	the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC	781:840	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	1	5	theme	aqueous	268:274	arg1	solutions					276:284	aqueous solutions	268:284	aqueous solutions	268:284	Due to the increasingly serious antibiotic-related pollution, it is crucial to develop novel green bioadsorbents to effectively remove antibiotics from aqueous solutions.					
36473529	5	6	theme	@	824:824	arg1	cellulose					825:833	Fe/ZIF-8@cellulose	816:833	Fe/ZIF-8@cellulose	816:833	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	4	7	theme	bioadsorbent	574:585	arg1	dosage					587:592	bioadsorbent dosage	574:592	bioadsorbent dosage	574:592	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	2	8	theme	@	371:371	arg1	cellulose					372:380	Fe/ZIF-8@cellulose	363:380	Fe/ZIF-8@cellulose	363:380	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	2	8	theme	@	371:371	arg1	cellulose					352:360	imidazolate frameworks-8 loaded cellulose	320:360	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	4	9	theme	initial	625:631	arg1	concentration					636:648	initial TC concentration	625:648	initial TC concentration	625:648	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	9	10	theme	antibiotics	1318:1328	arg1	performance					1341:1351	the antibiotics adsorption performance	1314:1351	the antibiotics adsorption performance	1314:1351	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	4	11	from	effects	563:569	arg1	behaviors					698:706	the TC adsorption behaviors	680:706	the TC adsorption behaviors	680:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	2	12	theme	Fe	302:303	arg1	aerogels					383:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	0	13	theme	tetracycline	94:105	arg1	removal					107:113	highly efficient tetracycline removal	77:113	highly efficient tetracycline removal	77:113	Bimetallic MOFs loaded cellulose as an environment friendly bioadsorbent for highly efficient tetracycline removal.					
36473529	9	14	theme	adsorption	1330:1339	arg1	performance					1341:1351	the antibiotics adsorption performance	1314:1351	the antibiotics adsorption performance	1314:1351	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	1	15	theme	serious	140:146	arg1	pollution					167:175	the increasingly serious antibiotic-related pollution	123:175	the increasingly serious antibiotic-related pollution	123:175	Due to the increasingly serious antibiotic-related pollution, it is crucial to develop novel green bioadsorbents to effectively remove antibiotics from aqueous solutions.					
36473529	5	16	theme	maximum	785:791	arg1	capacity					804:811	the maximum adsorption capacity	781:811	the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC	781:840	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	4	17	theme	TC	684:685	arg1	behaviors					698:706	the TC adsorption behaviors	680:706	the TC adsorption behaviors	680:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	0	18	theme	environment	39:49	arg1	bioadsorbent					60:71	an environment friendly bioadsorbent	36:71	an environment friendly bioadsorbent for highly efficient tetracycline removal	36:113	Bimetallic MOFs loaded cellulose as an environment friendly bioadsorbent for highly efficient tetracycline removal.					
36473529	5	19	theme	based	940:944	arg1	adsorbents					946:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	4	20	theme	TC	633:634	arg1	concentration					636:648	initial TC concentration	625:648	initial TC concentration	625:648	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	9	21	theme	finding	1233:1239	arg1	results					1218:1224	The results	1214:1224	The results of our finding	1214:1239	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	4	22	theme	adsorption	654:663	arg1	temperature					665:675	adsorption temperature	654:675	adsorption temperature	654:675	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	9	23	theme	cyclic	1437:1442	arg1	utilization					1444:1454	the cyclic utilization	1433:1454	the cyclic utilization	1433:1454	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	6	24	theme	TC	998:999	arg1	adsorption					1001:1010	TC adsorption	998:1010	TC adsorption	998:1010	The adsorption kinetics and isotherm of TC adsorption were also determined.					
36473529	7	25	theme	cellulose	1107:1115	arg1	aerogels					1117:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	2	26	theme	frameworks-8	332:343	arg1	cellulose					372:380	Fe/ZIF-8@cellulose	363:380	Fe/ZIF-8@cellulose	363:380	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	2	26	theme	frameworks-8	332:343	arg1	cellulose					352:360	imidazolate frameworks-8 loaded cellulose	320:360	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	10	27	theme	antibiotics	1545:1555	arg1	removal					1557:1563	the antibiotics removal	1541:1563	the antibiotics removal	1541:1563	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	0	28	theme	Bimetallic	0:9	arg1	MOFs					11:14	Bimetallic MOFs	0:14	Bimetallic MOFs	0:14	Bimetallic MOFs loaded cellulose as an environment friendly bioadsorbent for highly efficient tetracycline removal.					
36473529	4	29	theme	adsorption	608:617	arg1	time					619:622	adsorption time	608:622	adsorption time	608:622	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	2	30	theme	imidazolate	320:330	arg1	cellulose					372:380	Fe/ZIF-8@cellulose	363:380	Fe/ZIF-8@cellulose	363:380	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	2	30	theme	imidazolate	320:330	arg1	cellulose					352:360	imidazolate frameworks-8 loaded cellulose	320:360	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	8	31	theme	adsorption	1179:1188	arg1	mechanism					1190:1198	the TC adsorption mechanism	1172:1198	the TC adsorption mechanism	1172:1198	Most importantly, the TC adsorption mechanism was proposed.					
36473529	5	32	theme	reported	903:910	arg1	adsorbents					946:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	10	33	theme	Fe/ZIF-8	1510:1517	arg1	aerogels					1529:1536	the Fe/ZIF-8@cellulose aerogels	1506:1536	the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater	1506:1588	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	5	34	theme	Fe	764:765	arg1	introduction					748:759	the introduction	744:759	the introduction of Fe in the ZIF-8	744:778	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	2	35	theme	zeolitic	311:318	arg1	aerogels					383:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	1	36	theme	novel	203:207	arg1	bioadsorbents					215:227	novel green bioadsorbents	203:227	novel green bioadsorbents	203:227	Due to the increasingly serious antibiotic-related pollution, it is crucial to develop novel green bioadsorbents to effectively remove antibiotics from aqueous solutions.					
36473529	9	37	theme	valuable	1405:1412	arg1	matrix					1393:1398	the matrix	1389:1398	the matrix	1389:1398	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	9	37	theme	valuable	1405:1412	arg1	method					1414:1419	a valuable method	1403:1419	a valuable method to increase the cyclic utilization	1403:1454	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	6	38	theme	adsorption	1001:1010	arg1	isotherm					986:993	isotherm	986:993	isotherm	986:993	The adsorption kinetics and isotherm of TC adsorption were also determined.					
36473529	6	38	theme	adsorption	1001:1010	arg1	kinetics					973:980	adsorption kinetics	962:980	adsorption kinetics	962:980	The adsorption kinetics and isotherm of TC adsorption were also determined.					
36473529	7	39	theme	@	1106:1106	arg1	aerogels					1117:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	9	40	theme	Fe	1258:1259	arg1	doping					1261:1266	the Fe doping	1254:1266	the Fe doping into MOFs	1254:1276	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	9	40	theme	Fe	1258:1259	arg1	strategy					1294:1301	an effective strategy	1281:1301	an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization	1281:1454	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	2	41	theme	doped	305:309	arg1	aerogels					383:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	5	42	theme	ZIF-8	912:916	arg1	adsorbents					946:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	1	43	theme	green	209:213	arg1	bioadsorbents					215:227	novel green bioadsorbents	203:227	novel green bioadsorbents	203:227	Due to the increasingly serious antibiotic-related pollution, it is crucial to develop novel green bioadsorbents to effectively remove antibiotics from aqueous solutions.					
36473529	3	44	theme	@	431:431	arg1	aerogels					442:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	4	45	theme	time	619:622	arg1	effects					563:569	The effects	559:569	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors	559:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	10	46	theme	@	1518:1518	arg1	aerogels					1529:1536	the Fe/ZIF-8@cellulose aerogels	1506:1536	the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater	1506:1588	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	9	47	theme	cellulose	1376:1384	arg1	performance					1341:1351	the antibiotics adsorption performance	1314:1351	the antibiotics adsorption performance	1314:1351	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	9	47	theme	cellulose	1376:1384	arg1	application					1361:1371	the application	1357:1371	the application of cellulose	1357:1384	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	3	48	theme	cellulose	432:440	arg1	aerogels					442:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	7	49	theme	obtained	1089:1096	arg1	aerogels					1117:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	8	50	theme	TC	1176:1177	arg1	mechanism					1190:1198	the TC adsorption mechanism	1172:1198	the TC adsorption mechanism	1172:1198	Most importantly, the TC adsorption mechanism was proposed.					
36473529	10	51	from	aerogels	1529:1536	arg1	removal					1557:1563	the antibiotics removal	1541:1563	the antibiotics removal	1541:1563	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	3	52	theme	morphology	495:504	arg1	observation					506:516	morphology observation	495:516	morphology observation	495:516	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	0	53	theme	friendly	51:58	arg1	bioadsorbent					60:71	an environment friendly bioadsorbent	36:71	an environment friendly bioadsorbent for highly efficient tetracycline removal	36:113	Bimetallic MOFs loaded cellulose as an environment friendly bioadsorbent for highly efficient tetracycline removal.					
36473529	4	54	theme	dosage	587:592	arg1	effects					563:569	The effects	559:569	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors	559:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	2	55	theme	Fe/ZIF-8	363:370	arg1	cellulose					372:380	Fe/ZIF-8@cellulose	363:380	Fe/ZIF-8@cellulose	363:380	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	2	55	theme	Fe/ZIF-8	363:370	arg1	cellulose					352:360	imidazolate frameworks-8 loaded cellulose	320:360	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	3	56	theme	Fe/ZIF-8	423:430	arg1	aerogels					442:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	4	57	theme	pH	604:605	arg1	effects					563:569	The effects	559:569	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors	559:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	7	58	theme	Fe/ZIF-8	1098:1105	arg1	aerogels					1117:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	the obtained Fe/ZIF-8@cellulose aerogels	1085:1124	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	10	59	theme	practical	1569:1577	arg1	wastewater					1579:1588	practical wastewater	1569:1588	practical wastewater	1569:1588	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	7	60	theme	good	1136:1139	arg1	reusability					1141:1151	good reusability	1136:1151	good reusability	1136:1151	With the cellulose as the matrix to load Fe/ZIF-8, the obtained Fe/ZIF-8@cellulose aerogels exhibited good reusability.					
36473529	4	61	theme	solution	595:602	arg1	pH					604:605	solution pH	595:605	solution pH	595:605	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	2	62	theme	cellulose	352:360	arg1	aerogels					383:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	5	63	from	introduction	748:759	arg1	ZIF-8					774:778	the ZIF-8	770:778	the ZIF-8	770:778	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	4	64	theme	temperature	665:675	arg1	effects					563:569	The effects	559:569	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors	559:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	5	65	theme	cellulose	825:833	arg1	capacity					804:811	the maximum adsorption capacity	781:811	the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC	781:840	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
36473529	9	66	theme	effective	1284:1292	arg1	doping					1261:1266	the Fe doping	1254:1266	the Fe doping into MOFs	1254:1276	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	9	66	theme	effective	1284:1292	arg1	strategy					1294:1301	an effective strategy	1281:1301	an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization	1281:1454	The results of our finding suggest that the Fe doping into MOFs is an effective strategy to improve the antibiotics adsorption performance and the application of cellulose as the matrix is a valuable method to increase the cyclic utilization.					
36473529	2	67	theme	loaded	345:350	arg1	cellulose					372:380	Fe/ZIF-8@cellulose	363:380	Fe/ZIF-8@cellulose	363:380	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	2	67	theme	loaded	345:350	arg1	cellulose					352:360	imidazolate frameworks-8 loaded cellulose	320:360	Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels	302:390	In this study, Fe doped zeolitic imidazolate frameworks-8 loaded cellulose (Fe/ZIF-8@cellulose) aerogels were prepared.					
36473529	3	68	theme	chemical	522:529	arg1	compositions					531:542	chemical compositions	522:542	chemical compositions	522:542	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	10	69	theme	cellulose	1519:1527	arg1	aerogels					1529:1536	the Fe/ZIF-8@cellulose aerogels	1506:1536	the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater	1506:1588	This study highlights the potentials of applying the Fe/ZIF-8@cellulose aerogels in the antibiotics removal for practical wastewater.					
36473529	3	70	dep	observation	506:516	arg1	determination					544:556	determination	544:556	determination	544:556	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	4	71	theme	adsorption	687:696	arg1	behaviors					698:706	the TC adsorption behaviors	680:706	the TC adsorption behaviors	680:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	1	72	theme	antibiotic-related	148:165	arg1	pollution					167:175	the increasingly serious antibiotic-related pollution	123:175	the increasingly serious antibiotic-related pollution	123:175	Due to the increasingly serious antibiotic-related pollution, it is crucial to develop novel green bioadsorbents to effectively remove antibiotics from aqueous solutions.					
36473529	4	73	theme	concentration	636:648	arg1	effects					563:569	The effects	559:569	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors	559:706	The effects of bioadsorbent dosage, solution pH, adsorption time, initial TC concentration and adsorption temperature on the TC adsorption behaviors were systematically studied.					
36473529	3	74	theme	synthesized	411:421	arg1	aerogels					442:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels	407:449	The synthesized Fe/ZIF-8@cellulose aerogels were characterized experimentally including morphology observation and chemical compositions determination.					
36473529	6	75	theme	adsorption	962:971	arg1	kinetics					973:980	adsorption kinetics	962:980	adsorption kinetics	962:980	The adsorption kinetics and isotherm of TC adsorption were also determined.					
36473529	5	76	theme	loaded	918:923	arg1	adsorbents					946:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	the reported ZIF-8 loaded polysaccharide based adsorbents	899:955	Due to the introduction of Fe in the ZIF-8, the maximum adsorption capacity of Fe/ZIF-8@cellulose for TC could reach as high as 1359.2 mg/g, which is higher than the reported ZIF-8 loaded polysaccharide based adsorbents.					
35660439	0	0	theme	valorization	81:92	arg1	source					49:54	a promising source	37:54	a promising source of value-added compounds valorization	37:92	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	2	1	theme	protein	456:462	arg1	content					464:470	protein content	456:470	protein content	456:470	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	5	2	theme	food	1197:1200	arg1	applications					1226:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	4	3	theme	great	905:909	arg1	potential					911:919	great potential	905:919	great potential as a source of soluble protein	905:950	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	3	4	dep	rich	624:627	arg1	rich					624:627	rich	624:627	rich	624:627	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	4	dep	rich	624:627	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	4	dep	rich	624:627	arg1	%					590:590	50%	588:590	50%	588:590	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	4	dep	rich	624:627	arg1	fraction					553:560	The first fraction	543:560	The first fraction after acid treatment	543:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	0	5	theme	compounds	71:79	arg1	valorization					81:92	value-added compounds valorization	59:92	value-added compounds valorization	59:92	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	4	6	theme	solid	771:775	arg1	residue					777:783	the solid residue	767:783	the solid residue	767:783	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	4	6	theme	solid	771:775	arg1	soluble					790:796	soluble	790:796	soluble	790:796	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	4	6	theme	solid	771:775	arg1	insoluble					810:818	insoluble	810:818	insoluble	810:818	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	3	7	from	rich	624:627	arg1	phlorotannins					632:644	phlorotannins	632:644	phlorotannins (15 mg GAE/g)	632:658	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	7	from	rich	624:627	arg1	%					690:690	15-70%	685:690	15-70%	685:690	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	7	from	rich	624:627	arg1	fucoidans					674:682	bioactive fucoidans	664:682	bioactive fucoidans (15-70%)	664:691	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	7	from	rich	624:627	arg1	GAE/g					653:657	15 mg GAE/g	647:657	15 mg GAE/g	647:657	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	2	8	theme	composition	494:504	arg1	capacities					522:531	antioxidant capacities	510:531	antioxidant capacities	510:531	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	2	8	theme	composition	494:504	arg1	terms					435:439	terms	435:439	terms of lipid, ash, protein content, and the carbohydrate composition	435:504	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	1	9	from	year	163:166	arg1	Europe					180:185	Europe	180:185	Europe	180:185	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	1	10	theme	different	234:242	arg1	streams					266:272	different solid/liquid residual streams	234:272	different solid/liquid residual streams	234:272	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	2	11	theme	carbohydrate	481:492	arg1	composition					494:504	the carbohydrate composition	477:504	the carbohydrate composition	477:504	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	4	12	theme	biomass	886:892	arg1	biomass					886:892	the initial biomass	874:892	the initial biomass	874:892	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	4	12	theme	biomass	886:892	arg1	%					860:860	9%	859:860	9%	859:860	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	4	12	theme	biomass	886:892	arg1	%					869:869	5-8%	866:869	5-8% of the initial biomass	866:892	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	1	13	theme	solid/liquid	244:255	arg1	streams					266:272	different solid/liquid residual streams	234:272	different solid/liquid residual streams	234:272	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	3	14	theme	bioactive	664:672	arg1	fucoidans					674:682	bioactive fucoidans	664:682	bioactive fucoidans (15-70%)	664:691	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	14	theme	bioactive	664:672	arg1	%					690:690	15-70%	685:690	15-70%	685:690	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	15	from	fucoidans	674:682	arg1	%					590:590	50%	588:590	50%	588:590	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	15	from	fucoidans	674:682	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	15	from	fucoidans	674:682	arg1	rich					624:627	rich	624:627	rich	624:627	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	15	from	fucoidans	674:682	arg1	fraction					553:560	The first fraction	543:560	The first fraction after acid treatment	543:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	5	16	theme	waste	1071:1075	arg1	streams					1077:1083	these waste streams	1065:1083	these waste streams	1065:1083	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	5	17	theme	high	1103:1106	arg1	potential					1108:1116	their high potential	1097:1116	their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications	1097:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	5	18	theme	Valorization	1023:1034	arg1	strategies					1036:1045	Valorization strategies	1023:1045	Valorization strategies	1023:1045	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	3	19	from	phlorotannins	632:644	arg1	%					590:590	50%	588:590	50%	588:590	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	19	from	phlorotannins	632:644	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	19	from	phlorotannins	632:644	arg1	rich					624:627	rich	624:627	rich	624:627	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	19	from	phlorotannins	632:644	arg1	fraction					553:560	The first fraction	543:560	The first fraction after acid treatment	543:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	4	20	theme	initial	878:884	arg1	biomass					886:892	the initial biomass	874:892	the initial biomass	874:892	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	3	21	with	rich	624:627	arg1	degree					716:721	a high sulfation degree	699:721	a high sulfation degree in A. nodosum	699:735	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	1	22	theme	algae	171:175	arg1	year					163:166	year	163:166	year of algae in Europe	163:185	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	0	23	theme	industrial	9:18	arg1	waste					20:24	Alginate industrial waste	0:24	Alginate industrial waste	0:24	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	4	24	dep	insoluble	810:818	arg1	Ra					821:822	Ra	821:822	Ra	821:822	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	4	24	dep	insoluble	810:818	arg1	Rb					828:829	Rb	828:829	Rb	828:829	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	3	25	theme	first	547:551	arg1	%					590:590	50%	588:590	50%	588:590	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	25	theme	first	547:551	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	25	theme	first	547:551	arg1	rich					624:627	rich	624:627	rich	624:627	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	25	theme	first	547:551	arg1	fraction					553:560	The first fraction	543:560	The first fraction after acid treatment	543:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	0	26	theme	Alginate	0:7	arg1	waste					20:24	Alginate industrial waste	0:24	Alginate industrial waste	0:24	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	1	27	theme	residual	257:264	arg1	streams					266:272	different solid/liquid residual streams	234:272	different solid/liquid residual streams	234:272	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	4	28	dep	showed	898:903	arg1	%					955:955	30%	953:955	30% for S. latissima	953:972	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	1	29	theme	alginate	99:106	arg1	industry					108:115	The alginate industry	95:115	The alginate industry	95:115	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	5	30	theme	bioactive	1121:1129	arg1	ingredients					1171:1181	bioactive, texturizing or nutritional added-value ingredients	1121:1181	bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications	1121:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	3	31	theme	dry	607:609	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	5	32	theme	texturizing	1132:1142	arg1	ingredients					1171:1181	bioactive, texturizing or nutritional added-value ingredients	1121:1181	bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications	1121:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	2	33	theme	ash	451:453	arg1	capacities					522:531	antioxidant capacities	510:531	antioxidant capacities	510:531	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	2	33	theme	ash	451:453	arg1	terms					435:439	terms	435:439	terms of lipid, ash, protein content, and the carbohydrate composition	435:504	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	5	34	theme	nutritional	1147:1157	arg1	ingredients					1171:1181	bioactive, texturizing or nutritional added-value ingredients	1121:1181	bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications	1121:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	2	35	theme	antioxidant	510:520	arg1	capacities					522:531	antioxidant capacities	510:531	antioxidant capacities	510:531	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	3	36	theme	biomass	611:617	arg1	rich					624:627	rich	624:627	rich	624:627	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	36	theme	biomass	611:617	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	36	theme	biomass	611:617	arg1	%					590:590	50%	588:590	50%	588:590	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	36	theme	biomass	611:617	arg1	fraction					553:560	The first fraction	543:560	The first fraction after acid treatment	543:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	4	37	theme	soluble	936:942	arg1	protein					944:950	soluble protein	936:950	soluble protein	936:950	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	3	38	dep	%	590:590	arg1	ca.					584:586	ca.	584:586	ca.	584:586	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	2	39	theme	lipid	444:448	arg1	capacities					522:531	antioxidant capacities	510:531	antioxidant capacities	510:531	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	2	39	theme	lipid	444:448	arg1	terms					435:439	terms	435:439	terms of lipid, ash, protein content, and the carbohydrate composition	435:504	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	3	40	theme	initial	599:605	arg1	biomass					611:617	the initial dry biomass	595:617	the initial dry biomass	595:617	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	5	41	theme	feed	1203:1206	arg1	applications					1226:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	0	42	theme	promising	39:47	arg1	source					49:54	a promising source	37:54	a promising source of value-added compounds valorization	37:92	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	3	43	theme	acid	568:571	arg1	treatment					573:581	acid treatment	568:581	acid treatment	568:581	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	44	from	degree	716:721	arg1	nodosum					729:735	A. nodosum	726:735	A. nodosum	726:735	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	5	45	theme	pharmaceutical	1211:1224	arg1	applications					1226:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	4	46	theme	protein	944:950	arg1	source					926:931	a source	924:931	a source of soluble protein	924:950	Two fractions generated from the solid residue, one soluble and another insoluble (Ra and Rb, respectively), constituted 9% and 5-8% of the initial biomass and showed great potential as a source of soluble protein (30% for S. latissima), and cellulose (70%) or fucoidan, respectively.					
35660439	5	47	theme	added-value	1159:1169	arg1	ingredients					1171:1181	bioactive, texturizing or nutritional added-value ingredients	1121:1181	bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications	1121:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	0	48	theme	value-added	59:69	arg1	valorization					81:92	value-added compounds valorization	59:92	value-added compounds valorization	59:92	Alginate industrial waste streams as a promising source of value-added compounds valorization.					
35660439	5	49	theme	cosmetic	1187:1194	arg1	applications					1226:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	cosmetic, food, feed or pharmaceutical applications	1187:1237	Valorization strategies are suggested for these waste streams, evidencing their high potential as bioactive, texturizing or nutritional added-value ingredients for cosmetic, food, feed or pharmaceutical applications.					
35660439	1	50	theme	thousand	145:152	arg1	tons					154:157	more than hundred thousand tons	127:157	more than hundred thousand tons per year of algae in Europe	127:185	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	2	51	theme	residual	369:376	arg1	fractions					378:386	all residual fractions	365:386	all residual fractions	365:386	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	3	52	theme	high	701:704	arg1	degree					716:721	a high sulfation degree	699:721	a high sulfation degree in A. nodosum	699:735	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	2	53	theme	content	464:470	arg1	capacities					522:531	antioxidant capacities	510:531	antioxidant capacities	510:531	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	2	53	theme	content	464:470	arg1	terms					435:439	terms	435:439	terms of lipid, ash, protein content, and the carbohydrate composition	435:504	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	3	54	theme	15	647:648	arg1	mg					650:651	mg	650:651	mg	650:651	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	55	theme	sulfation	706:714	arg1	degree					716:721	a high sulfation degree	699:721	a high sulfation degree in A. nodosum	699:735	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	56	theme	mg	650:651	arg1	phlorotannins					632:644	phlorotannins	632:644	phlorotannins (15 mg GAE/g)	632:658	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	3	56	theme	mg	650:651	arg1	GAE/g					653:657	15 mg GAE/g	647:657	15 mg GAE/g	647:657	The first fraction after acid treatment (ca. 50% of the initial dry biomass) was rich in phlorotannins (15 mg GAE/g) and bioactive fucoidans (15-70%), with a high sulfation degree in A. nodosum.					
35660439	2	57	theme	generated	341:349	arg1	alginates					351:359	their generated alginates	335:359	their generated alginates	335:359	In this work, Saccharina latissima and Ascophyllum nodosum, their generated alginates and all residual fractions generated in the process were characterized in terms of lipid, ash, protein content, and the carbohydrate composition and antioxidant capacities analyzed.					
35660439	1	58	theme	algae	217:221	arg1	%					208:208	80%	206:208	80% of the algae biomass as different solid/liquid residual streams	206:272	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35660439	1	58	theme	algae	217:221	arg1	algae					217:221	the algae	213:221	the algae biomass as different solid/liquid residual streams	213:272	The alginate industry processes more than hundred thousand tons per year of algae in Europe, discarding around 80% of the algae biomass as different solid/liquid residual streams.					
35973483	2	0	dep	%	480:480	arg1	lignin					493:498	lignin	493:498	lignin	493:498	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin.					
35973483	1	1	from	constituents	173:184	arg1	deserticola					285:295	cultivated Cistanche deserticola	264:295	cultivated Cistanche deserticola (C. deserticola)	264:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	9	2	theme	MAPKs	1534:1538	arg1	pathways					1550:1557	NF-κB pathways	1544:1557	NF-κB pathways	1544:1557	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	9	2	theme	MAPKs	1534:1538	arg1	activation					1520:1529	the activation	1516:1529	the activation of MAPKs	1516:1538	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	3	3	from	glucose	536:542	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	9	4	theme	vaccine	1652:1658	arg1	exploitation					1660:1671	vaccine exploitation	1652:1671	vaccine exploitation	1652:1671	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	1	5	theme	cultivated	264:273	arg1	deserticola					285:295	cultivated Cistanche deserticola	264:295	cultivated Cistanche deserticola (C. deserticola)	264:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	7	6	theme	Th1/Th2	1223:1229	arg1	cytokines					1231:1239	Th1/Th2 cytokines	1223:1239	Th1/Th2 cytokines	1223:1239	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	8	7	theme	DCs	1424:1426	arg1	candidates					1410:1419	the membrane receptor candidates	1388:1419	the membrane receptor candidates of DCs	1388:1426	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	7	theme	DCs	1424:1426	arg1	TLR4					1378:1381	TLR4	1378:1381	TLR4	1378:1381	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	7	theme	DCs	1424:1426	arg1	TLR2					1369:1372	TLR2	1369:1372	TLR2	1369:1372	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	9	8	theme	NF-κB	1544:1548	arg1	pathways					1550:1557	NF-κB pathways	1544:1557	NF-κB pathways	1544:1557	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	3	9	from	rhamnose	545:552	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	1	10	theme	Cistanche	275:283	arg1	deserticola					285:295	cultivated Cistanche deserticola	264:295	cultivated Cistanche deserticola (C. deserticola)	264:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	8	11	theme	Blocking	1338:1345	arg1	assays					1347:1352	Blocking assays	1338:1352	Blocking assays	1338:1352	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	5	12	theme	IFN-γ	1010:1014	arg1	production					1016:1025	IFN-γ production	1010:1025	IFN-γ production	1010:1025	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	9	13	theme	Western	1429:1435	arg1	blot					1437:1440	Western blot	1429:1440	Western blot	1429:1440	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	8	14	theme	membrane	1392:1399	arg1	candidates					1410:1419	the membrane receptor candidates	1388:1419	the membrane receptor candidates of DCs	1388:1426	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	14	theme	membrane	1392:1399	arg1	TLR4					1378:1381	TLR4	1378:1381	TLR4	1378:1381	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	14	theme	membrane	1392:1399	arg1	TLR2					1369:1372	TLR2	1369:1372	TLR2	1369:1372	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	4	15	dep	in	684:685	arg1	vitro					687:691	vitro	687:691	vitro	687:691	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	5	16	dep	in	890:891	arg1	vivo					893:896	vivo	893:896	vivo	893:896	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	7	17	theme	allogeneic	1187:1196	arg1	proliferation					1205:1217	allogeneic T-cell proliferation	1187:1217	allogeneic T-cell proliferation	1187:1217	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	9	18	theme	dose-/time-related	1564:1581	arg1	manner					1583:1588	a dose-/time-related manner	1562:1588	a dose-/time-related manner	1562:1588	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	5	19	theme	in	890:891	arg1	experiment					898:907	An in vivo experiment	887:907	An in vivo experiment	887:907	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	0	20	theme	Chemical	0:7	arg1	composition					9:19	Chemical composition	0:19	Chemical composition	0:19	Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator.					
35973483	5	21	theme	antigen-specific	974:989	arg1	activation					998:1007	antigen-specific T-cell activation	974:1007	antigen-specific T-cell activation	974:1007	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	1	22	theme	adjuvant	187:194	arg1	effects					196:202	adjuvant effects	187:202	adjuvant effects	187:202	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	0	23	theme	adjuvant	25:32	arg1	properties					34:43	adjuvant properties	25:43	adjuvant properties	25:43	Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator.					
35973483	5	24	theme	T-cell	991:996	arg1	activation					998:1007	antigen-specific T-cell activation	974:1007	antigen-specific T-cell activation	974:1007	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	5	25	theme	DC	1049:1050	arg1	activation					1052:1061	DC activation	1049:1061	DC activation	1049:1061	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	1	26	from	deserticola	285:295	arg1	mechanisms					220:229	underlying mechanisms	209:229	underlying mechanisms	209:229	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	26	from	deserticola	285:295	arg1	polysaccharides					243:257	purified polysaccharides	234:257	purified polysaccharides from cultivated Cistanche deserticola (C. deserticola)	234:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	26	from	deserticola	285:295	arg1	constituents					173:184	the constituents	169:184	the constituents	169:184	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	26	from	deserticola	285:295	arg1	effects					196:202	adjuvant effects	187:202	adjuvant effects	187:202	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	4	27	theme	splenocyte	760:769	arg1	proliferation					771:783	splenocyte proliferation	760:783	splenocyte proliferation	760:783	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	3	28	from	mannose	581:587	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	7	29	theme	MHC	1167:1169	arg1	II					1171:1172	MHC II	1167:1172	MHC II	1167:1172	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	7	30	theme	T-cell	1198:1203	arg1	proliferation					1205:1217	allogeneic T-cell proliferation	1187:1217	allogeneic T-cell proliferation	1187:1217	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	4	31	theme	DC	842:843	arg1	maturation					846:855	dendritic cell (DC) maturation	826:855	dendritic cell (DC) maturation	826:855	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	6	32	theme	Th1-biased	1091:1100	arg1	response					1102:1109	a Th1-biased response	1089:1109	a Th1-biased response	1089:1109	Notably, CCDP-2 elicited a Th1-biased response.					
35973483	9	33	theme	immune-enhancing	1471:1486	arg1	activities					1488:1497	the immune-enhancing activities	1467:1497	the immune-enhancing activities	1467:1497	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	2	34	theme	carbohydrate-lignin	440:458	arg1	complexes					460:468	carbohydrate-lignin complexes	440:468	carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin	440:498	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin.					
35973483	2	34	theme	carbohydrate-lignin	440:458	arg1	macromolecules					319:332	Two macromolecules	315:332	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola	315:406	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin.					
35973483	1	35	theme	underlying	209:218	arg1	mechanisms					220:229	underlying mechanisms	209:229	underlying mechanisms	209:229	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	0	36	theme	macromolecules	52:65	arg1	composition					9:19	Chemical composition	0:19	Chemical composition	0:19	Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator.					
35973483	0	36	theme	macromolecules	52:65	arg1	properties					34:43	adjuvant properties	25:43	adjuvant properties	25:43	Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator.					
35973483	3	37	theme	7.22	625:628	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	4	38	theme	endotoxin-free	718:731	arg1	CCDP-1					733:738	endotoxin-free CCDP-1	718:738	endotoxin-free CCDP-1	718:738	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	9	39	with	CCDP-2	1455:1460	arg1	activities					1488:1497	the immune-enhancing activities	1467:1497	the immune-enhancing activities	1467:1497	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	8	40	theme	receptor	1401:1408	arg1	candidates					1410:1419	the membrane receptor candidates	1388:1419	the membrane receptor candidates of DCs	1388:1426	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	40	theme	receptor	1401:1408	arg1	TLR4					1378:1381	TLR4	1378:1381	TLR4	1378:1381	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	8	40	theme	receptor	1401:1408	arg1	TLR2					1369:1372	TLR2	1369:1372	TLR2	1369:1372	Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs.					
35973483	1	41	from	effects	196:202	arg1	deserticola					285:295	cultivated Cistanche deserticola	264:295	cultivated Cistanche deserticola (C. deserticola)	264:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	5	42	theme	OVA-specific	940:951	arg1	production					962:971	OVA-specific antibody production	940:971	OVA-specific antibody production	940:971	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	9	43	theme	adjuvant	1639:1646	arg1	CCDP-2					1455:1460	CCDP-2	1455:1460	CCDP-2 with the immune-enhancing activities	1455:1497	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	9	43	theme	adjuvant	1639:1646	arg1	Th1/Th2					1631:1637	a more balanced Th1/Th2	1615:1637	a more balanced Th1/Th2 adjuvant for vaccine exploitation	1615:1671	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	1	44	from	mechanisms	220:229	arg1	deserticola					285:295	cultivated Cistanche deserticola	264:295	cultivated Cistanche deserticola (C. deserticola)	264:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	45	dep	deserticola	285:295	arg1	deserticola					301:311	C. deserticola	298:311	C. deserticola	298:311	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	3	46	theme	molar	609:613	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	2	47	with	complexes	460:468	arg1	%					480:480	44.1 %	475:480	44.1 %	475:480	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin.					
35973483	2	47	with	complexes	460:468	arg1	%					491:491	43.8 %	486:491	43.8 %	486:491	Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin.					
35973483	5	48	theme	antibody	953:960	arg1	production					962:971	OVA-specific antibody production	940:971	OVA-specific antibody production	940:971	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	3	49	from	galactose	555:563	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	9	50	theme	balanced	1622:1629	arg1	CCDP-2					1455:1460	CCDP-2	1455:1460	CCDP-2 with the immune-enhancing activities	1455:1497	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	9	50	theme	balanced	1622:1629	arg1	Th1/Th2					1631:1637	a more balanced Th1/Th2	1615:1637	a more balanced Th1/Th2 adjuvant for vaccine exploitation	1615:1671	Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.					
35973483	7	51	from	DCs	1324:1326	arg1	vitro					1331:1335	vitro	1331:1335	vitro	1331:1335	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	7	52	theme	TNF-α	1275:1279	arg1	production					1281:1290	TNF-α production	1275:1290	TNF-α production	1275:1290	Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro.					
35973483	3	53	dep	7.22	625:628	arg1	6.57:8.48:4.20:2.72:1.00					655:678	6.57:8.48:4.20:2.72:1.00	655:678	6.57:8.48:4.20:2.72:1.00	655:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	3	53	dep	7.22	625:628	arg1	5.98:2.51:1.81:1.00					631:649	5.98:2.51:1.81:1.00	631:649	5.98:2.51:1.81:1.00	631:649	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	4	54	theme	cell	836:839	arg1	maturation					846:855	dendritic cell (DC) maturation	826:855	dendritic cell (DC) maturation	826:855	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	3	55	from	arabinose	566:574	arg1	ratios					615:620	the molar ratios	605:620	the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00	605:678	CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00.					
35973483	1	56	theme	purified	234:241	arg1	polysaccharides					243:257	purified polysaccharides	234:257	purified polysaccharides from cultivated Cistanche deserticola (C. deserticola)	234:312	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	5	57	theme	IL-4	1028:1031	arg1	production					1033:1042	IL-4 production	1028:1042	IL-4 production	1028:1042	An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation.					
35973483	4	58	theme	dendritic	826:834	arg1	maturation					846:855	dendritic cell (DC) maturation	826:855	dendritic cell (DC) maturation	826:855	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	4	59	theme	in	684:685	arg1	experiment					693:702	An in vitro experiment	681:702	An in vitro experiment	681:702	An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1.					
35973483	1	60	theme	polysaccharides	243:257	arg1	mechanisms					220:229	underlying mechanisms	209:229	underlying mechanisms	209:229	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	60	theme	polysaccharides	243:257	arg1	constituents					173:184	the constituents	169:184	the constituents	169:184	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
35973483	1	60	theme	polysaccharides	243:257	arg1	effects					196:202	adjuvant effects	187:202	adjuvant effects	187:202	The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola).					
36590867	6	0	theme	composition	913:923	arg1	abundance					880:888	relative abundance	871:888	relative abundance of bacterial taxonomic composition	871:923	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	6	0	theme	composition	913:923	arg1	indexes					859:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	10	1	theme	second	1566:1571	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	13	2	theme	third	1964:1968	arg1	week					1970:1973	the second and third week	1949:1973	the second and third week	1949:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	8	3	theme	hospitalization	1166:1180	arg1	week					1149:1152	each week	1144:1152	each week of the NICU hospitalization	1144:1180	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	6	4	theme	bacterial	893:901	arg1	composition					913:923	bacterial taxonomic composition	893:923	bacterial taxonomic composition	893:923	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	15	5	dep	female	2247:2252	arg1	neonates					2271:2278	preterm neonates	2263:2278	preterm neonates	2263:2278	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	8	6	theme	preterm	1183:1189	arg1	females					1191:1197	preterm females	1183:1197	preterm females	1183:1197	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	6	theme	preterm	1183:1189	arg1	Results					1133:1139	Results	1133:1139	Results In each week of the NICU hospitalization	1133:1180	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	13	7	theme	significant	1830:1840	arg1	abundance					1842:1850	a significant abundance	1828:1850	a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week	1828:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	8	8	theme	gut	1281:1283	arg1	microbiota					1285:1294	gut microbiota	1281:1294	gut microbiota	1281:1294	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	10	9	theme	hospitalization	1609:1623	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	13	10	theme	second	1953:1958	arg1	week					1970:1973	the second and third week	1949:1973	the second and third week	1949:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	2	11	theme	unit	323:326	arg1	hospitalization					335:349	their neonatal intensive care unit (NICU) hospitalization	293:349	their neonatal intensive care unit (NICU) hospitalization	293:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	15	12	theme	microbiota	2181:2190	arg1	compositions					2192:2203	the distinct gut microbiota compositions	2164:2203	the distinct gut microbiota compositions	2164:2203	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	6	13	theme	R	966:966	arg1	packages					968:975	R packages	966:975	R packages	966:975	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	7	14	theme	microbiome	1084:1093	arg1	profiles					1095:1102	gut microbiome profiles	1080:1102	gut microbiome profiles	1080:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	2	15	theme	intensive	308:316	arg1	NICU					329:332	NICU	329:332	NICU	329:332	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	2	15	theme	intensive	308:316	arg1	unit					323:326	intensive care unit	308:326	their neonatal intensive care unit (NICU) hospitalization	293:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	15	16	theme	distinct	2168:2175	arg1	compositions					2192:2203	the distinct gut microbiota compositions	2164:2203	the distinct gut microbiota compositions	2164:2203	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	8	17	theme	distinguished	1227:1239	arg1	indices					1253:1259	significantly distinguished β-diversity indices	1213:1259	significantly distinguished β-diversity indices	1213:1259	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	5	18	theme	gene	709:712	arg1	regions					714:720	The 16S rRNA V4 gene regions	693:720	The 16S rRNA V4 gene regions of the stool samples	693:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	7	19	theme	metabolic	1057:1065	arg1	functions					1067:1075	predicted metabolic functions	1047:1075	predicted metabolic functions of gut microbiome profiles	1047:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	2	20	theme	weekly	221:226	arg1	patterns					228:235	sex-specific weekly patterns	208:235	sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization	208:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	15	21	theme	preterm	2263:2269	arg1	neonates					2271:2278	preterm neonates	2263:2278	preterm neonates	2263:2278	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	12	22	theme	biosynthesis	1747:1758	arg1	"					1759:1759	"lipopolysaccharide biosynthesis"	1727:1759	"lipopolysaccharide biosynthesis"	1727:1759	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	8	23	contain	had	1209:1211	arg2	indices					1253:1259	significantly distinguished β-diversity indices	1213:1259	significantly distinguished β-diversity indices	1213:1259	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	23	contain	had	1209:1211	arg1	males					1203:1207	males	1203:1207	males	1203:1207	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	23	contain	had	1209:1211	arg1	females					1191:1197	preterm females	1183:1197	preterm females	1183:1197	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	23	contain	had	1209:1211	arg1	Results					1133:1139	Results	1133:1139	Results In each week of the NICU hospitalization	1133:1180	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	23	contain	had	1209:1211	arg2	compositions					1265:1276	compositions	1265:1276	compositions of gut microbiota	1265:1294	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	7	24	theme	weekly	991:996	arg1	patterns					1012:1019	Sex-specific weekly compositional patterns	978:1019	Sex-specific weekly compositional patterns of the gut microbiome	978:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	1	25	theme	preterm	147:153	arg1	infants					155:161	preterm infants	147:161	preterm infants	147:161	Objectives The gut microbiota among preterm infants is shaped by sex and feeding types.					
36590867	1	26	dep	Objectives	111:120	arg1	shaped					166:171	shaped	166:171	is shaped by sex and feeding types	163:196	Objectives The gut microbiota among preterm infants is shaped by sex and feeding types.					
36590867	13	27	theme	"	1944:1944	arg1	abundance					1842:1850	a significant abundance	1828:1850	a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week	1828:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	3	28	from	effect	403:408	arg1	development					431:441	the weekly development	420:441	the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization	420:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	2	29	theme	microbiome	244:253	arg1	profiles					255:262	gut microbiome profiles	240:262	gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization	240:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	0	30	theme	intensive	79:87	arg1	hospitalization					94:108	the neonatal intensive care hospitalization	66:108	the neonatal intensive care hospitalization	66:108	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	4	31	dep	Methods	524:530	arg1	analysis					552:559	This secondary data analysis	532:559	Methods This secondary data analysis	524:559	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	15	32	theme	functional	2219:2228	arg1	profiles					2230:2237	predicted functional profiles	2209:2237	predicted functional profiles	2209:2237	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	8	33	from	Results	1133:1139	arg1	week					1149:1152	each week	1144:1152	each week of the NICU hospitalization	1144:1180	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	13	34	theme	glycan	1910:1915	arg1	biosynthesis					1917:1928	glycan biosynthesis	1910:1928	glycan biosynthesis	1910:1928	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	14	35	theme	preterm	2022:2028	arg1	profiles					2054:2061	preterm neonatal gut microbiome profiles	2022:2061	preterm neonatal gut microbiome profiles	2022:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	14	36	theme	hospitalization	2100:2114	arg1	weeks					2082:2086	the first 4 weeks	2070:2086	the first 4 weeks of the NICU hospitalization	2070:2114	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	13	37	theme	intracellular	1869:1881	arg1	molecules					1894:1902	intracellular structural molecules	1869:1902	intracellular structural molecules	1869:1902	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	5	38	theme	stool	729:733	arg1	samples					735:741	the stool samples	725:741	the stool samples	725:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	10	39	theme	metabolic	1485:1493	arg1	pathways					1495:1502	The predicted metabolic pathways	1471:1502	The predicted metabolic pathways	1471:1502	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	10	39	theme	metabolic	1485:1493	arg1	different					1523:1531	different	1523:1531	different	1523:1531	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	0	40	theme	neonatal	70:77	arg1	hospitalization					94:108	the neonatal intensive care hospitalization	66:108	the neonatal intensive care hospitalization	66:108	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	13	41	theme	molecules	1894:1902	arg1	"					1903:1903	"membrane and intracellular structural molecules"	1855:1903	"membrane and intracellular structural molecules"	1855:1903	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	0	42	theme	Sex-specific	0:11	arg1	profiles					28:35	Sex-specific gut microbiome profiles	0:35	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.	0:109	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	9	43	theme	protection	1366:1375	arg1	Bifidobacterium					1347:1361	Bifidobacterium	1347:1361	Bifidobacterium	1347:1361	Both females and males had significantly enriched Bifidobacterium, a protection feature, in stool samples collected in the third week compared with those in the second week.					
36590867	9	43	theme	protection	1366:1375	arg1	feature					1377:1383	a protection feature	1364:1383	a protection feature	1364:1383	Both females and males had significantly enriched Bifidobacterium, a protection feature, in stool samples collected in the third week compared with those in the second week.					
36590867	4	44	theme	data	547:550	arg1	analysis					552:559	This secondary data analysis	532:559	Methods This secondary data analysis	524:559	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	15	45	theme	clinical	2125:2132	arg1	interventions					2134:2146	Further clinical interventions	2117:2146	Further clinical interventions	2117:2146	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	3	46	theme	gut	463:465	arg1	microbiota					467:476	preterm neonatal gut microbiota	446:476	preterm neonatal gut microbiota	446:476	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	0	47	theme	microbiome	17:26	arg1	profiles					28:35	Sex-specific gut microbiome profiles	0:35	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.	0:109	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	3	48	theme	sex	413:415	arg1	effect					403:408	the effect	399:408	the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization	399:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	14	49	theme	first	2074:2078	arg1	weeks					2082:2086	the first 4 weeks	2070:2086	the first 4 weeks of the NICU hospitalization	2070:2114	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	13	50	theme	membrane	1856:1863	arg1	"					1903:1903	"membrane and intracellular structural molecules"	1855:1903	"membrane and intracellular structural molecules"	1855:1903	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	3	51	theme	preterm	446:452	arg1	microbiota					467:476	preterm neonatal gut microbiota	446:476	preterm neonatal gut microbiota	446:476	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	9	52	theme	stool	1389:1393	arg1	samples					1395:1401	stool samples	1389:1401	stool samples collected in the third week compared with those in the second week	1389:1468	Both females and males had significantly enriched Bifidobacterium, a protection feature, in stool samples collected in the third week compared with those in the second week.					
36590867	6	53	theme	weekly	842:847	arg1	indexes					859:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	1	54	dep	sex	176:178	arg1	types					192:196	types	192:196	types	192:196	Objectives The gut microbiota among preterm infants is shaped by sex and feeding types.					
36590867	3	55	theme	first	485:489	arg1	weeks					493:497	the first 4 weeks	481:497	the first 4 weeks of NICU hospitalization	481:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	5	56	theme	SILVA	782:786	arg1	database					792:799	the SILVA 132 database	778:799	the SILVA 132 database	778:799	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	4	57	dep	January	628:634	arg1	to					641:642	to	641:642	to	641:642	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	4	57	dep	January	628:634	arg1	February					644:651	February	644:651	February	644:651	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	14	58	theme	microbiome	2043:2052	arg1	profiles					2054:2061	preterm neonatal gut microbiome profiles	2022:2061	preterm neonatal gut microbiome profiles	2022:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	4	59	theme	stool	599:603	arg1	samples					605:611	261 stool samples	595:611	261 stool samples collected from January 2014 to February 2015 in the Northeastern United States	595:690	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	3	60	theme	NICU	502:505	arg1	hospitalization					507:521	NICU hospitalization	502:521	NICU hospitalization	502:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	4	61	with	neonates	581:588	arg1	samples					605:611	261 stool samples	595:611	261 stool samples collected from January 2014 to February 2015 in the Northeastern United States	595:690	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	6	62	theme	taxonomic	903:911	arg1	composition					913:923	bacterial taxonomic composition	893:923	bacterial taxonomic composition	893:923	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	12	63	theme	third	1789:1793	arg1	week					1807:1810	the second, third, and fourth week	1777:1810	the second, third, and fourth week	1777:1810	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	4	64	theme	preterm	573:579	arg1	neonates					581:588	28 preterm neonates	570:588	28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States	570:690	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	13	65	contain	had	1824:1826	arg2	abundance					1842:1850	a significant abundance	1828:1850	a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week	1828:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	13	65	contain	had	1824:1826	arg1	Males					1813:1817	Males	1813:1817	Males	1813:1817	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	2	66	theme	neonatal	299:306	arg1	hospitalization					335:349	their neonatal intensive care unit (NICU) hospitalization	293:349	their neonatal intensive care unit (NICU) hospitalization	293:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	8	67	theme	NICU	1161:1164	arg1	hospitalization					1166:1180	the NICU hospitalization	1157:1180	the NICU hospitalization	1157:1180	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	10	68	theme	fourth	1585:1590	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	12	69	contain	had	1705:1707	arg1	Males					1686:1690	Males	1686:1690	Males	1686:1690	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	12	69	contain	had	1705:1707	arg2	abundance					1714:1722	more abundance	1709:1722	more abundance of "lipopolysaccharide biosynthesis" than females	1709:1772	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	4	70	theme	Northeastern	665:676	arg1	States					685:690	the Northeastern United States	661:690	the Northeastern United States	661:690	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	9	71	theme	second	1458:1463	arg1	week					1465:1468	the second week	1454:1468	the second week	1454:1468	Both females and males had significantly enriched Bifidobacterium, a protection feature, in stool samples collected in the third week compared with those in the second week.					
36590867	6	72	theme	relative	871:878	arg1	abundance					880:888	relative abundance	871:888	relative abundance of bacterial taxonomic composition	871:923	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	7	73	theme	profiles	1095:1102	arg1	functions					1067:1075	predicted metabolic functions	1047:1075	predicted metabolic functions of gut microbiome profiles	1047:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	7	73	theme	profiles	1095:1102	arg1	patterns					1012:1019	Sex-specific weekly compositional patterns	978:1019	Sex-specific weekly compositional patterns of the gut microbiome	978:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	15	74	theme	gut	2177:2179	arg1	compositions					2192:2203	the distinct gut microbiota compositions	2164:2203	the distinct gut microbiota compositions	2164:2203	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	12	75	theme	second	1781:1786	arg1	week					1807:1810	the second, third, and fourth week	1777:1810	the second, third, and fourth week	1777:1810	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	10	76	theme	NICU	1604:1607	arg1	hospitalization					1609:1623	the NICU hospitalization	1600:1623	the NICU hospitalization	1600:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	5	77	theme	16S	697:699	arg1	regions					714:720	The 16S rRNA V4 gene regions	693:720	The 16S rRNA V4 gene regions of the stool samples	693:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	15	78	theme	Further	2117:2123	arg1	interventions					2134:2146	Further clinical interventions	2117:2146	Further clinical interventions	2117:2146	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	2	79	theme	care	318:321	arg1	NICU					329:332	NICU	329:332	NICU	329:332	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	2	79	theme	care	318:321	arg1	unit					323:326	intensive care unit	308:326	their neonatal intensive care unit (NICU) hospitalization	293:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	8	80	theme	microbiota	1285:1294	arg1	compositions					1265:1276	compositions	1265:1276	compositions of gut microbiota	1265:1294	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	8	80	theme	microbiota	1285:1294	arg1	indices					1253:1259	significantly distinguished β-diversity indices	1213:1259	significantly distinguished β-diversity indices	1213:1259	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	5	81	theme	V4	706:707	arg1	regions					714:720	The 16S rRNA V4 gene regions	693:720	The 16S rRNA V4 gene regions of the stool samples	693:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	2	82	theme	gut	240:242	arg1	profiles					255:262	gut microbiome profiles	240:262	gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization	240:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	7	83	theme	predicted	1047:1055	arg1	functions					1067:1075	predicted metabolic functions	1047:1075	predicted metabolic functions of gut microbiome profiles	1047:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	7	84	theme	gut	1028:1030	arg1	microbiome					1032:1041	the gut microbiome	1024:1041	the gut microbiome	1024:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	1	85	theme	gut	126:128	arg1	microbiota					130:139	The gut microbiota	122:139	The gut microbiota among preterm infants	122:161	Objectives The gut microbiota among preterm infants is shaped by sex and feeding types.					
36590867	8	86	theme	β-diversity	1241:1251	arg1	indices					1253:1259	significantly distinguished β-diversity indices	1213:1259	significantly distinguished β-diversity indices	1213:1259	Results In each week of the NICU hospitalization, preterm females and males had significantly distinguished β-diversity indices and compositions of gut microbiota.					
36590867	7	87	theme	gut	1080:1082	arg1	profiles					1095:1102	gut microbiome profiles	1080:1102	gut microbiome profiles	1080:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	13	88	theme	biosynthesis	1917:1928	arg1	"					1944:1944	"glycan biosynthesis and metabolism"	1909:1944	"glycan biosynthesis and metabolism"	1909:1944	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	7	89	theme	microbiome	1032:1041	arg1	functions					1067:1075	predicted metabolic functions	1047:1075	predicted metabolic functions of gut microbiome profiles	1047:1102	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	7	89	theme	microbiome	1032:1041	arg1	patterns					1012:1019	Sex-specific weekly compositional patterns	978:1019	Sex-specific weekly compositional patterns of the gut microbiome	978:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	2	90	theme	preterm	270:276	arg1	infants					278:284	preterm infants	270:284	preterm infants during their neonatal intensive care unit (NICU) hospitalization	270:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	12	91	theme	lipopolysaccharide	1728:1745	arg1	biosynthesis					1747:1758	lipopolysaccharide biosynthesis	1728:1758	"lipopolysaccharide biosynthesis"	1727:1759	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	13	92	theme	metabolism	1934:1943	arg1	"					1944:1944	"glycan biosynthesis and metabolism"	1909:1944	"glycan biosynthesis and metabolism"	1909:1944	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	5	93	theme	samples	735:741	arg1	regions					714:720	The 16S rRNA V4 gene regions	693:720	The 16S rRNA V4 gene regions of the stool samples	693:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	2	94	theme	profiles	255:262	arg1	patterns					228:235	sex-specific weekly patterns	208:235	sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization	208:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	7	95	theme	compositional	998:1010	arg1	patterns					1012:1019	Sex-specific weekly compositional patterns	978:1019	Sex-specific weekly compositional patterns of the gut microbiome	978:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	12	96	theme	"	1759:1759	arg1	abundance					1714:1722	more abundance	1709:1722	more abundance of "lipopolysaccharide biosynthesis" than females	1709:1772	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	10	97	from	females	1541:1547	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	4	98	theme	United	678:683	arg1	States					685:690	the Northeastern United States	661:690	the Northeastern United States	661:690	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	13	99	theme	"	1903:1903	arg1	abundance					1842:1850	a significant abundance	1828:1850	a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week	1828:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	0	100	theme	care	89:92	arg1	hospitalization					94:108	the neonatal intensive care hospitalization	66:108	the neonatal intensive care hospitalization	66:108	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	7	101	theme	Sex-specific	978:989	arg1	patterns					1012:1019	Sex-specific weekly compositional patterns	978:1019	Sex-specific weekly compositional patterns of the gut microbiome	978:1041	Sex-specific weekly compositional patterns of the gut microbiome and predicted metabolic functions of gut microbiome profiles were compared, respectively.					
36590867	15	102	theme	predicted	2209:2217	arg1	profiles					2230:2237	predicted functional profiles	2209:2237	predicted functional profiles	2209:2237	Further clinical interventions should consider the distinct gut microbiota compositions and predicted functional profiles between female and male preterm neonates.					
36590867	12	103	theme	more	1709:1712	arg1	abundance					1714:1722	more abundance	1709:1722	more abundance of "lipopolysaccharide biosynthesis" than females	1709:1772	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	10	104	from	males	1553:1557	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	5	105	theme	rRNA	701:704	arg1	regions					714:720	The 16S rRNA V4 gene regions	693:720	The 16S rRNA V4 gene regions of the stool samples	693:741	The 16S rRNA V4 gene regions of the stool samples were sequenced and aligned against the SILVA 132 database by using Mothur 1.42.3.					
36590867	14	106	theme	neonatal	2030:2037	arg1	profiles					2054:2061	preterm neonatal gut microbiome profiles	2022:2061	preterm neonatal gut microbiome profiles	2022:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	14	107	theme	NICU	2095:2098	arg1	hospitalization					2100:2114	the NICU hospitalization	2091:2114	the NICU hospitalization	2091:2114	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	13	108	theme	structural	1883:1892	arg1	molecules					1894:1902	intracellular structural molecules	1869:1902	intracellular structural molecules	1869:1902	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	0	109	theme	gut	13:15	arg1	profiles					28:35	Sex-specific gut microbiome profiles	0:35	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.	0:109	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	14	110	theme	weekly	2003:2008	arg1	patterns					2010:2017	the weekly patterns	1999:2017	the weekly patterns of preterm neonatal gut microbiome profiles	1999:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	10	111	theme	predicted	1475:1483	arg1	pathways					1495:1502	The predicted metabolic pathways	1471:1502	The predicted metabolic pathways	1471:1502	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	10	111	theme	predicted	1475:1483	arg1	different					1523:1531	different	1523:1531	different	1523:1531	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	3	112	theme	weekly	424:429	arg1	development					431:441	the weekly development	420:441	the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization	420:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	11	113	contain	had	1649:1651	arg1	females					1631:1637	females	1631:1637	females	1631:1637	Both females and males had significantly abundant pathways.					
36590867	11	113	contain	had	1649:1651	arg2	pathways					1676:1683	significantly abundant pathways	1653:1683	significantly abundant pathways	1653:1683	Both females and males had significantly abundant pathways.					
36590867	11	113	contain	had	1649:1651	arg1	males					1643:1647	males	1643:1647	males	1643:1647	Both females and males had significantly abundant pathways.					
36590867	3	114	theme	microbiota	467:476	arg1	development					431:441	the weekly development	420:441	the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization	420:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	0	115	theme	preterm	43:49	arg1	infants					51:57	preterm infants	43:57	preterm infants	43:57	Sex-specific gut microbiome profiles among preterm infants during the neonatal intensive care hospitalization.					
36590867	6	116	theme	diversity	849:857	arg1	indexes					859:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	14	117	theme	Conclusions	1976:1986	arg1	Sex					1988:1990	Conclusions Sex	1976:1990	Conclusions Sex	1976:1990	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	3	118	theme	neonatal	454:461	arg1	microbiota					467:476	preterm neonatal gut microbiota	446:476	preterm neonatal gut microbiota	446:476	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	6	119	theme	sex-specific	829:840	arg1	indexes					859:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes	825:865	The sex-specific weekly diversity indexes and relative abundance of bacterial taxonomic composition were generated by Mothur and analyzed by R packages.					
36590867	13	120	from	abundance	1842:1850	arg1	week					1970:1973	the second and third week	1949:1973	the second and third week	1949:1973	Males also had a significant abundance of "membrane and intracellular structural molecules" and "glycan biosynthesis and metabolism" in the second and third week.					
36590867	4	121	theme	secondary	537:545	arg1	analysis					552:559	This secondary data analysis	532:559	Methods This secondary data analysis	524:559	Methods This secondary data analysis included 28 preterm neonates with 261 stool samples collected from January 2014 to February 2015 in the Northeastern United States.					
36590867	14	122	theme	profiles	2054:2061	arg1	patterns					2010:2017	the weekly patterns	1999:2017	the weekly patterns of preterm neonatal gut microbiome profiles	1999:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	2	123	theme	sex-specific	208:219	arg1	patterns					228:235	sex-specific weekly patterns	208:235	sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization	208:349	However, sex-specific weekly patterns of gut microbiome profiles among preterm infants during their neonatal intensive care unit (NICU) hospitalization remain unclear.					
36590867	14	124	theme	gut	2039:2041	arg1	profiles					2054:2061	preterm neonatal gut microbiome profiles	2022:2061	preterm neonatal gut microbiome profiles	2022:2061	Conclusions Sex shaped the weekly patterns of preterm neonatal gut microbiome profiles during the first 4 weeks of the NICU hospitalization.					
36590867	9	125	theme	third	1420:1424	arg1	week					1426:1429	the third week	1416:1429	the third week compared with those in the second week	1416:1468	Both females and males had significantly enriched Bifidobacterium, a protection feature, in stool samples collected in the third week compared with those in the second week.					
36590867	12	126	theme	fourth	1800:1805	arg1	week					1807:1810	the second, third, and fourth week	1777:1810	the second, third, and fourth week	1777:1810	Males consistently had more abundance of "lipopolysaccharide biosynthesis" than females in the second, third, and fourth week.					
36590867	10	127	theme	third	1574:1578	arg1	week					1592:1595	the second, third, and fourth week	1562:1595	the second, third, and fourth week of the NICU hospitalization	1562:1623	The predicted metabolic pathways were significantly different between females and males in the second, third, and fourth week of the NICU hospitalization.					
36590867	11	128	theme	abundant	1667:1674	arg1	pathways					1676:1683	significantly abundant pathways	1653:1683	significantly abundant pathways	1653:1683	Both females and males had significantly abundant pathways.					
36590867	3	129	from	development	431:441	arg1	weeks					493:497	the first 4 weeks	481:497	the first 4 weeks of NICU hospitalization	481:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36590867	3	130	theme	hospitalization	507:521	arg1	weeks					493:497	the first 4 weeks	481:497	the first 4 weeks of NICU hospitalization	481:521	This study aimed to investigate the effect of sex on the weekly development of preterm neonatal gut microbiota in the first 4 weeks of NICU hospitalization.					
36958451	5	0	theme	CG/Bx/ZnO	796:804	arg1	hydrogel					806:813	CG/Bx/ZnO hydrogel	796:813	CG/Bx/ZnO hydrogel	796:813	Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m2/g with 3.41 nm pore radius.					
36958451	7	1	theme	adsorption	1144:1153	arg1	efficiency					1130:1139	the overall efficiency	1118:1139	the overall efficiency of adsorption	1118:1153	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	9	2	theme	Thermodynamic	1382:1394	arg1	results					1402:1408	Thermodynamic study results	1382:1408	Thermodynamic study results	1382:1408	Thermodynamic study results show that adsorption is spontaneous and endothermic.					
36958451	5	3	theme	Surface	780:786	arg1	area					788:791	Surface area	780:791	Surface area of CG/Bx/ZnO hydrogel	780:813	Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m2/g with 3.41 nm pore radius.					
36958451	5	4	theme	hydrogel	806:813	arg1	area					788:791	Surface area	780:791	Surface area of CG/Bx/ZnO hydrogel	780:813	Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m2/g with 3.41 nm pore radius.					
36958451	6	5	from	pH	1032:1033	arg1	10 mg					1011:1015	10 mg	1011:1015	10 mg of hydrogel at pH of 4 in 8 h at room temperature	1011:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	6	5	from	pH	1032:1033	arg1	8 h					1043:1045	8 h	1043:1045	8 h at room temperature	1043:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	8	6	theme	adsorption	1251:1260	arg1	process					1262:1268	The adsorption process	1247:1268	The adsorption process	1247:1268	The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity.					
36958451	4	7	theme	rough	734:738	arg1	surface					740:746	the rough surface	730:746	the rough surface	730:746	Surface morphology of as-synthesized hydrogel revealed the rough surface, which was determined by FESEM.					
36958451	6	8	theme	hydrogel	1020:1027	arg1	10 mg					1011:1015	10 mg	1011:1015	10 mg of hydrogel at pH of 4 in 8 h at room temperature	1011:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	0	9	theme	response	113:120	arg1	methodology					130:140	response surface methodology	113:140	response surface methodology	113:140	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	10	10	theme	excellent	1499:1507	arg1	repeatability					1509:1521	excellent repeatability	1499:1521	excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles	1499:1582	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	10	11	theme	minimal	1528:1534	arg1	loss					1536:1539	minimal loss	1528:1539	minimal loss in norfloxacin adsorption	1528:1565	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	2	12	theme	biodegradable	314:326	arg1	adsorbents					343:352	efficient, biodegradable, and non-toxic adsorbents	303:352	efficient, biodegradable, and non-toxic adsorbents	303:352	Hence, to mitigate this effect, efficient, biodegradable, and non-toxic adsorbents are required to be developed.					
36958451	10	13	from	loss	1536:1539	arg1	adsorption					1556:1565	norfloxacin adsorption	1544:1565	norfloxacin adsorption	1544:1565	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	3	14	from	water	668:672	arg1	adsorption					637:646	efficient adsorption	627:646	efficient adsorption of norfloxacin from water	627:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	14	from	water	668:672	arg1	norfloxacin					651:661	norfloxacin	651:661	norfloxacin from water	651:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	6	15	from	4	1038:1038	arg1	8 h					1043:1045	8 h	1043:1045	8 h at room temperature	1043:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	16	theme	κ-carrageenan	574:586	arg1	hydrogel					600:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel	555:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	555:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	17	link	borax-cross-linked	555:572	arg1	hydrogel					600:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel	555:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	555:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	6	18	theme	removal	925:931	arg1	efficiency					933:942	99.4 % removal efficiency	918:942	99.4 % removal efficiency	918:942	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	19	with	crosslinking	480:491	arg1	borax					498:502	borax	498:502	borax	498:502	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	19	with	crosslinking	480:491	arg1	incorporation					508:520	incorporation	508:520	incorporation	508:520	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	8	20	theme	Langmuir	1325:1332	arg1	isotherm					1334:1341	the pseudo-second-order model and Langmuir isotherm	1291:1341	isotherm	1334:1341	The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity.					
36958451	2	21	theme	efficient	303:311	arg1	adsorbents					343:352	efficient, biodegradable, and non-toxic adsorbents	303:352	efficient, biodegradable, and non-toxic adsorbents	303:352	Hence, to mitigate this effect, efficient, biodegradable, and non-toxic adsorbents are required to be developed.					
36958451	3	22	from	adsorption	637:646	arg1	water					668:672	water	668:672	water	668:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	1	23	theme	increased	195:203	arg1	prescription					205:216	increased prescription	195:216	increased prescription	195:216	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	0	24	theme	surface	122:128	arg1	methodology					130:140	response surface methodology	113:140	response surface methodology	113:140	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	6	25	theme	%	923:923	arg1	efficiency					933:942	99.4 % removal efficiency	918:942	99.4 % removal efficiency	918:942	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	26	dep	polymer	412:418	arg1	having					421:426	having	421:426	having multiple functional groups	421:453	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	7	27	theme	Box-Behnken	1211:1221	arg1	model					1240:1244	Box-Behnken composite design model	1211:1244	Box-Behnken composite design model	1211:1244	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	8	28	theme	1282.05 mg/g	1348:1359	arg1	capacity					1372:1379	1282.05 mg/g adsorption capacity	1348:1379	1282.05 mg/g adsorption capacity	1348:1379	The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity.					
36958451	6	29	theme	99.4 	918:922	arg1	%					923:923	%	923:923	%	923:923	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	6	30	from	8 h	1043:1045	arg1	pH					1032:1033	pH	1032:1033	pH of 4 in 8 h at room temperature	1032:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	31	theme	multiple	428:435	arg1	groups					448:453	multiple functional groups	428:453	multiple functional groups	428:453	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	0	32	theme	Non-toxic	0:8	arg1	hydrogel					46:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel	0:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.	0:141	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	9	33	theme	study	1396:1400	arg1	results					1402:1408	Thermodynamic study results	1382:1408	Thermodynamic study results	1382:1408	Thermodynamic study results show that adsorption is spontaneous and endothermic.					
36958451	10	34	theme	norfloxacin	1544:1554	arg1	adsorption					1556:1565	norfloxacin adsorption	1544:1565	norfloxacin adsorption	1544:1565	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	6	35	from	temperature	1055:1065	arg1	8 h					1043:1045	8 h	1043:1045	8 h at room temperature	1043:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	2	36	theme	non-toxic	333:341	arg1	adsorbents					343:352	efficient, biodegradable, and non-toxic adsorbents	303:352	efficient, biodegradable, and non-toxic adsorbents	303:352	Hence, to mitigate this effect, efficient, biodegradable, and non-toxic adsorbents are required to be developed.					
36958451	1	37	theme	easy	222:225	arg1	dispensing					227:236	easy dispensing	222:236	easy dispensing	222:236	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	0	38	theme	κ-carrageenan/ZnO	28:44	arg1	hydrogel					46:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel	0:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.	0:141	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	6	39	theme	norfloxacin	994:1004	arg1	20 mg/L					983:989	20 mg/L	983:989	20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature	983:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	7	40	theme	optimized	1083:1091	arg1	parameters					1097:1106	Experimentally optimized key parameters	1068:1106	Experimentally optimized key parameters affecting the overall efficiency of adsorption	1068:1153	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	6	41	with	20 mg/L	983:989	arg1	10 mg					1011:1015	10 mg	1011:1015	10 mg of hydrogel at pH of 4 in 8 h at room temperature	1011:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	7	42	theme	overall	1122:1128	arg1	efficiency					1130:1139	the overall efficiency	1118:1139	the overall efficiency of adsorption	1118:1153	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	8	43	theme	pseudo-second-order	1295:1313	arg1	model					1315:1319	the pseudo-second-order model and Langmuir isotherm	1291:1341	model	1315:1319	The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity.					
36958451	0	44	theme	biodegradable	14:26	arg1	hydrogel					46:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel	0:53	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.	0:141	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	7	45	theme	key	1093:1095	arg1	parameters					1097:1106	Experimentally optimized key parameters	1068:1106	Experimentally optimized key parameters affecting the overall efficiency of adsorption	1068:1153	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	10	46	theme	CG/Bx/ZnO	1467:1475	arg1	hydrogel					1477:1484	The CG/Bx/ZnO hydrogel	1463:1484	The CG/Bx/ZnO hydrogel	1463:1484	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	3	47	theme	CG/Bx/ZnO	589:597	arg1	hydrogel					600:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel	555:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	555:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	6	48	theme	room	1050:1053	arg1	temperature					1055:1065	room temperature	1050:1065	room temperature	1050:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	4	49	theme	hydrogel	712:719	arg1	morphology					683:692	Surface morphology	675:692	Surface morphology of as-synthesized hydrogel	675:719	Surface morphology of as-synthesized hydrogel revealed the rough surface, which was determined by FESEM.					
36958451	4	50	theme	Surface	675:681	arg1	morphology					683:692	Surface morphology	675:692	Surface morphology of as-synthesized hydrogel	675:719	Surface morphology of as-synthesized hydrogel revealed the rough surface, which was determined by FESEM.					
36958451	6	51	theme	20 mg/L	983:989	arg1	level					974:978	a dosage level	965:978	a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature	965:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	52	theme	functional	437:446	arg1	groups					448:453	multiple functional groups	428:453	multiple functional groups	428:453	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	1	53	theme	antibiotic	241:250	arg1	drugs					252:256	antibiotic drugs	241:256	antibiotic drugs universally	241:268	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	5	54	theme	3.41 nm	847:853	arg1	radius					860:865	3.41 nm pore radius	847:865	3.41 nm pore radius	847:865	Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m2/g with 3.41 nm pore radius.					
36958451	1	55	theme	drugs	252:256	arg1	prescription					205:216	increased prescription	195:216	increased prescription	195:216	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	1	55	theme	drugs	252:256	arg1	dispensing					227:236	easy dispensing	222:236	easy dispensing	222:236	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	3	56	theme	natural	404:410	arg1	polymer					412:418	a natural polymer	402:418	a natural polymer	402:418	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	56	theme	natural	404:410	arg1	Carrageenan					384:394	Carrageenan	384:394	Carrageenan (CG)	384:399	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	7	57	theme	design	1233:1238	arg1	model					1240:1244	Box-Behnken composite design model	1211:1244	Box-Behnken composite design model	1211:1244	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	6	58	theme	adsorption	885:894	arg1	studies					896:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	8	59	theme	adsorption	1361:1370	arg1	capacity					1372:1379	1282.05 mg/g adsorption capacity	1348:1379	1282.05 mg/g adsorption capacity	1348:1379	The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity.					
36958451	0	60	theme	adsorptive	59:68	arg1	removal					70:76	adsorptive removal	59:76	adsorptive removal of norfloxacin	59:91	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	6	61	theme	dosage	967:972	arg1	level					974:978	a dosage level	965:978	a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature	965:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	7	62	theme	composite	1223:1231	arg1	model					1240:1244	Box-Behnken composite design model	1211:1244	Box-Behnken composite design model	1211:1244	Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model.					
36958451	6	63	theme	batch	879:883	arg1	studies					896:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	0	64	dep	hydrogel	46:53	arg1	Optimization					94:105	Optimization	94:105	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.	0:141	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	1	65	theme	Antibiotic	143:152	arg1	resistance					154:163	Antibiotic resistance	143:163	Antibiotic resistance	143:163	Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally.					
36958451	4	66	theme	as-synthesized	697:710	arg1	hydrogel					712:719	as-synthesized hydrogel	697:719	as-synthesized hydrogel	697:719	Surface morphology of as-synthesized hydrogel revealed the rough surface, which was determined by FESEM.					
36958451	6	67	theme	Systematic	868:877	arg1	studies					896:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies	868:902	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	3	68	theme	norfloxacin	651:661	arg1	adsorption					637:646	efficient adsorption	627:646	efficient adsorption of norfloxacin from water	627:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	69	used	used	618:621	arg2	hydrogel					600:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel	555:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	555:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	6	70	theme	4	1038:1038	arg1	pH					1032:1033	pH	1032:1033	pH of 4 in 8 h at room temperature	1032:1065	Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature.					
36958451	0	71	theme	norfloxacin	81:91	arg1	removal					70:76	adsorptive removal	59:76	adsorptive removal of norfloxacin	59:91	Non-toxic and biodegradable κ-carrageenan/ZnO hydrogel for adsorptive removal of norfloxacin: Optimization using response surface methodology.					
36958451	3	72	theme	efficient	627:635	arg1	adsorption					637:646	efficient adsorption	627:646	efficient adsorption of norfloxacin from water	627:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	73	theme	ZnO	525:527	arg1	nanoparticles					529:541	ZnO nanoparticles	525:541	ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	525:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	10	74	with	repeatability	1509:1521	arg1	loss					1536:1539	minimal loss	1528:1539	minimal loss in norfloxacin adsorption	1528:1565	The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.					
36958451	3	75	theme	borax-cross-linked	555:572	arg1	hydrogel					600:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel	555:607	borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water	555:672	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	5	76	theme	pore	855:858	arg1	radius					860:865	3.41 nm pore radius	847:865	3.41 nm pore radius	847:865	Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m2/g with 3.41 nm pore radius.					
36958451	3	77	theme	nanoparticles	529:541	arg1	borax					498:502	borax	498:502	borax	498:502	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
36958451	3	77	theme	nanoparticles	529:541	arg1	incorporation					508:520	incorporation	508:520	incorporation	508:520	Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water.					
35551949	9	0	theme	contact	1340:1346	arg1	angle					1348:1352	the contact angle	1336:1352	the contact angle of the aerogel surface	1336:1375	After functionalized by octadecyl trichlorosilane (OTS), the contact angle of the aerogel surface was 151.80°.					
35551949	1	1	theme	nanofibers	196:205	arg1	addition					165:172	the addition	161:172	the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI)	161:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	3	2	theme	composite	532:540	arg1	CMP					552:554	CMP	552:554	CMP	552:554	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	3	2	theme	composite	532:540	arg1	aerogels					542:549	the CNF/MMT/PEI composite aerogels	516:549	the CNF/MMT/PEI composite aerogels (CMP)	516:555	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	10	3	theme	lipophilic	1490:1499	arg1	properties					1501:1510	hydrophobic and lipophilic properties	1474:1510	hydrophobic and lipophilic properties	1474:1510	Meanwhile, the CMP-30 was transformed from hydrophilic and lipophilic properties to hydrophobic and lipophilic properties.					
35551949	7	4	with	CR	1011:1012	arg1	capacity					1034:1041	the adsorption capacity	1019:1041	the adsorption capacity of 3114 mg/g calculated by the Langmuir model	1019:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	9	5	theme	octadecyl	1303:1311	arg1	OTS					1330:1332	OTS	1330:1332	OTS	1330:1332	After functionalized by octadecyl trichlorosilane (OTS), the contact angle of the aerogel surface was 151.80°.					
35551949	9	5	theme	octadecyl	1303:1311	arg1	trichlorosilane					1313:1327	octadecyl trichlorosilane	1303:1327	octadecyl trichlorosilane (OTS)	1303:1333	After functionalized by octadecyl trichlorosilane (OTS), the contact angle of the aerogel surface was 151.80°.					
35551949	5	6	theme	adsorption	682:691	arg1	properties					693:702	The adsorption properties	678:702	The adsorption properties	678:702	The adsorption properties and mechanism of the CMP were discussed, using Congo red (CR) dye as an adsorbate.					
35551949	7	7	theme	cellulose	950:958	arg1	distribution					934:945	the surface charge distribution	915:945	the surface charge distribution of cellulose	915:958	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	3	8	theme	good	562:565	arg1	properties					578:587	good mechanical properties	562:587	good mechanical properties	562:587	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	1	9	theme	solution	283:290	arg1	blending					292:299	solution blending	283:299	solution blending	283:299	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	5	10	theme	red	757:759	arg1	dye					766:768	Congo red (CR) dye	751:768	Congo red (CR) dye	751:768	The adsorption properties and mechanism of the CMP were discussed, using Congo red (CR) dye as an adsorbate.					
35551949	5	10	theme	red	757:759	arg1	adsorbate					776:784	an adsorbate	773:784	an adsorbate	773:784	The adsorption properties and mechanism of the CMP were discussed, using Congo red (CR) dye as an adsorbate.					
35551949	10	11	theme	hydrophobic	1474:1484	arg1	properties					1501:1510	hydrophobic and lipophilic properties	1474:1510	hydrophobic and lipophilic properties	1474:1510	Meanwhile, the CMP-30 was transformed from hydrophilic and lipophilic properties to hydrophobic and lipophilic properties.					
35551949	8	12	theme	molecular	1262:1270	arg1	layer					1272:1276	a single molecular layer	1253:1276	a single molecular layer	1253:1276	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	6	13	with	structure	854:862	arg1	pores					878:882	abundant pores	869:882	abundant pores	869:882	The results showed that the CMP formed a three-dimensional network structure with abundant pores.					
35551949	4	14	theme	chemical	606:613	arg1	structure					615:623	chemical structure	606:623	chemical structure	606:623	The morphology, chemical structure and thermal stability of the CMP were characterized.					
35551949	0	15	theme	functionalization	42:58	arg1	performance					27:37	Preparation and adsorption performance	0:37	Preparation and adsorption performance of functionalization	0:58	Preparation and adsorption performance of functionalization cellulose-based composite aerogel.					
35551949	0	16	theme	Preparation	0:10	arg1	performance					27:37	Preparation and adsorption performance	0:37	Preparation and adsorption performance of functionalization	0:58	Preparation and adsorption performance of functionalization cellulose-based composite aerogel.					
35551949	8	17	theme	pseudo-second-order	1156:1174	arg1	model					1184:1188	the pseudo-second-order kinetic model	1152:1188	the pseudo-second-order kinetic model	1152:1188	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	1	18	theme	functionalization	103:119	arg1	aerogels					147:154	functionalization cellulose-based composite aerogels	103:154	functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI)	103:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	19	with	aerogels	147:154	arg1	addition					165:172	the addition	161:172	the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI)	161:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	10	20	theme	lipophilic	1449:1458	arg1	properties					1460:1469	lipophilic properties	1449:1469	lipophilic properties	1449:1469	Meanwhile, the CMP-30 was transformed from hydrophilic and lipophilic properties to hydrophobic and lipophilic properties.					
35551949	7	21	theme	surface	919:925	arg1	distribution					934:945	the surface charge distribution	915:945	the surface charge distribution of cellulose	915:958	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	1	22	theme	cellulose-based	121:135	arg1	aerogels					147:154	functionalization cellulose-based composite aerogels	103:154	functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI)	103:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	8	23	theme	Langmuir	1194:1201	arg1	model					1212:1216	Langmuir isotherm model	1194:1216	Langmuir isotherm model	1194:1216	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	5	24	theme	CMP	725:727	arg1	mechanism					708:716	mechanism	708:716	mechanism of the CMP	708:727	The adsorption properties and mechanism of the CMP were discussed, using Congo red (CR) dye as an adsorbate.					
35551949	5	24	theme	CMP	725:727	arg1	properties					693:702	The adsorption properties	678:702	The adsorption properties	678:702	The adsorption properties and mechanism of the CMP were discussed, using Congo red (CR) dye as an adsorbate.					
35551949	7	25	theme	charge	927:932	arg1	distribution					934:945	the surface charge distribution	915:945	the surface charge distribution of cellulose	915:958	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	1	26	theme	composite	137:145	arg1	aerogels					147:154	functionalization cellulose-based composite aerogels	103:154	functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI)	103:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	3	27	theme	bond	486:489	arg1	synergism					464:472	the synergism	460:472	the synergism of hydrogen bond and chemical bond	460:507	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	0	28	theme	adsorption	16:25	arg1	performance					27:37	Preparation and adsorption performance	0:37	Preparation and adsorption performance of functionalization	0:58	Preparation and adsorption performance of functionalization cellulose-based composite aerogel.					
35551949	1	29	theme	freeze-drying	305:317	arg1	technology					319:328	freeze-drying technology	305:328	freeze-drying technology	305:328	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	7	30	theme	Langmuir	1074:1081	arg1	model					1083:1087	the Langmuir model	1070:1087	the Langmuir model	1070:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	6	31	theme	abundant	869:876	arg1	pores					878:882	abundant pores	869:882	abundant pores	869:882	The results showed that the CMP formed a three-dimensional network structure with abundant pores.					
35551949	8	32	theme	single	1255:1260	arg1	layer					1272:1276	a single molecular layer	1253:1276	a single molecular layer	1253:1276	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	3	33	theme	amidation	436:444	arg1	reaction					446:453	amidation reaction	436:453	amidation reaction	436:453	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	8	34	theme	adsorption	1094:1103	arg1	more					1134:1137	more	1134:1137	more	1134:1137	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	34	theme	adsorption	1094:1103	arg1	process					1105:1111	The adsorption process	1090:1111	The adsorption process of CMP-30 for CR	1090:1128	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	35	with	line	1142:1145	arg1	model					1212:1216	Langmuir isotherm model	1194:1216	Langmuir isotherm model	1194:1216	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	35	with	line	1142:1145	arg1	model					1184:1188	the pseudo-second-order kinetic model	1152:1188	the pseudo-second-order kinetic model	1152:1188	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	36	theme	isotherm	1203:1210	arg1	model					1212:1216	Langmuir isotherm model	1194:1216	Langmuir isotherm model	1194:1216	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	9	37	theme	surface	1369:1375	arg1	angle					1348:1352	the contact angle	1336:1352	the contact angle of the aerogel surface	1336:1375	After functionalized by octadecyl trichlorosilane (OTS), the contact angle of the aerogel surface was 151.80°.					
35551949	3	38	theme	hydrogen	477:484	arg1	bond					486:489	hydrogen bond	477:489	hydrogen bond	477:489	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	0	39	theme	composite	76:84	arg1	aerogel					86:92	composite aerogel	76:92	composite aerogel	76:92	Preparation and adsorption performance of functionalization cellulose-based composite aerogel.					
35551949	3	40	theme	CNF/MMT/PEI	520:530	arg1	CMP					552:554	CMP	552:554	CMP	552:554	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	3	40	theme	CNF/MMT/PEI	520:530	arg1	aerogels					542:549	the CNF/MMT/PEI composite aerogels	516:549	the CNF/MMT/PEI composite aerogels (CMP)	516:555	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	6	41	theme	network	846:852	arg1	structure					854:862	a three-dimensional network structure	826:862	a three-dimensional network structure with abundant pores	826:882	The results showed that the CMP formed a three-dimensional network structure with abundant pores.					
35551949	9	42	theme	aerogel	1361:1367	arg1	surface					1369:1375	the aerogel surface	1357:1375	the aerogel surface	1357:1375	After functionalized by octadecyl trichlorosilane (OTS), the contact angle of the aerogel surface was 151.80°.					
35551949	7	43	theme	3114 mg/g	1046:1054	arg1	capacity					1034:1041	the adsorption capacity	1019:1041	the adsorption capacity of 3114 mg/g calculated by the Langmuir model	1019:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	6	44	theme	three-dimensional	828:844	arg1	structure					854:862	a three-dimensional network structure	826:862	a three-dimensional network structure with abundant pores	826:882	The results showed that the CMP formed a three-dimensional network structure with abundant pores.					
35551949	1	45	theme	cellulose	186:194	arg1	polyethyleneimine					240:256	polyethyleneimine	240:256	polyethyleneimine (PEI)	240:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	45	theme	cellulose	186:194	arg1	montmorillonite					214:228	montmorillonite	214:228	montmorillonite (MMT)	214:234	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	45	theme	cellulose	186:194	arg1	nanofibers					196:205	carboxyl cellulose nanofibers	177:205	carboxyl cellulose nanofibers (CNF)	177:211	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	45	theme	cellulose	186:194	arg1	CNF					208:210	CNF	208:210	CNF	208:210	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	2	46	theme	cellulose	356:364	arg1	framework					366:374	the cellulose framework	352:374	the cellulose framework	352:374	MMT was blended into the cellulose framework as a reinforcing agent.					
35551949	7	47	theme	CMP	1003:1005	arg1	performance					988:998	the adsorption performance	973:998	the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model	973:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	7	48	theme	adsorption	1023:1032	arg1	capacity					1034:1041	the adsorption capacity	1019:1041	the adsorption capacity of 3114 mg/g calculated by the Langmuir model	1019:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	3	49	theme	chemical	495:502	arg1	bond					504:507	chemical bond	495:507	chemical bond	495:507	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	3	50	theme	mechanical	567:576	arg1	properties					578:587	good mechanical properties	562:587	good mechanical properties	562:587	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	4	51	theme	thermal	629:635	arg1	stability					637:645	thermal stability	629:645	thermal stability	629:645	The morphology, chemical structure and thermal stability of the CMP were characterized.					
35551949	8	52	theme	CMP-30	1116:1121	arg1	more					1134:1137	more	1134:1137	more	1134:1137	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	52	theme	CMP-30	1116:1121	arg1	process					1105:1111	The adsorption process	1090:1111	The adsorption process of CMP-30 for CR	1090:1128	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	8	53	theme	kinetic	1176:1182	arg1	model					1184:1188	the pseudo-second-order kinetic model	1152:1188	the pseudo-second-order kinetic model	1152:1188	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	3	54	theme	bond	504:507	arg1	synergism					464:472	the synergism	460:472	the synergism of hydrogen bond and chemical bond	460:507	PEI combined with cellulose through amidation reaction, and the synergism of hydrogen bond and chemical bond helped the CNF/MMT/PEI composite aerogels (CMP) with good mechanical properties.					
35551949	8	55	theme	layer	1272:1276	arg1	adsorption					1239:1248	chemical adsorption	1230:1248	chemical adsorption of a single molecular layer	1230:1276	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	4	56	theme	CMP	654:656	arg1	morphology					594:603	The morphology	590:603	The morphology	590:603	The morphology, chemical structure and thermal stability of the CMP were characterized.					
35551949	4	56	theme	CMP	654:656	arg1	structure					615:623	chemical structure	606:623	chemical structure	606:623	The morphology, chemical structure and thermal stability of the CMP were characterized.					
35551949	4	56	theme	CMP	654:656	arg1	stability					637:645	thermal stability	629:645	thermal stability	629:645	The morphology, chemical structure and thermal stability of the CMP were characterized.					
35551949	1	57	theme	carboxyl	177:184	arg1	polyethyleneimine					240:256	polyethyleneimine	240:256	polyethyleneimine (PEI)	240:262	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	57	theme	carboxyl	177:184	arg1	montmorillonite					214:228	montmorillonite	214:228	montmorillonite (MMT)	214:234	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	57	theme	carboxyl	177:184	arg1	nanofibers					196:205	carboxyl cellulose nanofibers	177:205	carboxyl cellulose nanofibers (CNF)	177:211	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	1	57	theme	carboxyl	177:184	arg1	CNF					208:210	CNF	208:210	CNF	208:210	Herein, functionalization cellulose-based composite aerogels with the addition of carboxyl cellulose nanofibers (CNF), montmorillonite (MMT) and polyethyleneimine (PEI) were fabricated by solution blending and freeze-drying technology.					
35551949	7	58	theme	PEI	901:903	arg1	addition					889:896	The addition	885:896	The addition of PEI	885:903	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	8	59	theme	chemical	1230:1237	arg1	adsorption					1239:1248	chemical adsorption	1230:1248	chemical adsorption of a single molecular layer	1230:1276	The adsorption process of CMP-30 for CR was more in line with the pseudo-second-order kinetic model and Langmuir isotherm model, indicating chemical adsorption of a single molecular layer.					
35551949	7	60	theme	adsorption	977:986	arg1	performance					988:998	the adsorption performance	973:998	the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model	973:1087	The addition of PEI regulated the surface charge distribution of cellulose and improved the adsorption performance of CMP for CR with the adsorption capacity of 3114 mg/g calculated by the Langmuir model.					
35551949	2	61	theme	reinforcing	381:391	arg1	MMT					331:333	MMT	331:333	MMT	331:333	MMT was blended into the cellulose framework as a reinforcing agent.					
35551949	2	61	theme	reinforcing	381:391	arg1	agent					393:397	a reinforcing agent	379:397	a reinforcing agent	379:397	MMT was blended into the cellulose framework as a reinforcing agent.					
36239117	7	0	theme	transparent	1249:1259	arg1	appearance					1261:1270	a transparent appearance	1247:1270	a transparent appearance under visible daylight	1247:1293	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	2	1	theme	photoluminescent	365:380	arg1	notes					409:413	currency notes	400:413	currency notes characterized by optically changeable inks and highly fluorescent positions	400:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	2	1	theme	photoluminescent	365:380	arg1	surfaces					382:389	multicolored or photoluminescent surfaces	349:389	multicolored or photoluminescent surfaces	349:389	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	2	2	from	detection	336:344	arg1	notes					409:413	currency notes	400:413	currency notes characterized by optically changeable inks and highly fluorescent positions	400:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	2	2	from	detection	336:344	arg1	surfaces					382:389	multicolored or photoluminescent surfaces	349:389	multicolored or photoluminescent surfaces	349:389	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	12	3	dep	HIGHLIGHTS	1808:1817	arg1	ink					1832:1834	Novel smart ink	1820:1834	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid	1808:1885	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid was developed.					
36239117	11	4	theme	rheological	1704:1714	arg1	properties					1716:1725	The rheological properties	1700:1725	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples	1700:1791	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	3	5	theme	photochromic	586:597	arg1	ink					599:601	Novel photochromic ink	580:601	Novel photochromic ink	580:601	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	4	6	theme	nanoscale	804:812	arg1	ink					824:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	7	theme	acid	940:943	arg1	agent					953:957	a polyacrylic acid binding agent	926:957	a polyacrylic acid binding agent	926:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	8	8	theme	photoluminescence	1362:1378	arg1	spectra					1380:1386	photoluminescence spectra	1362:1386	photoluminescence spectra	1362:1386	The CIE Lab parameters and photoluminescence spectra were studied under visible light and ultraviolet irradiation.					
36239117	7	9	theme	paper	1222:1226	arg1	surface					1228:1234	paper surface	1222:1234	paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light	1222:1332	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	11	10	theme	behavior	1749:1756	arg1	properties					1716:1725	The rheological properties	1700:1725	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples	1700:1791	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	1	11	theme	fingerprint	206:216	arg1	analysis					218:225	fingerprint analysis	206:225	fingerprint analysis	206:225	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	8	12	theme	CIE	1339:1341	arg1	parameters					1347:1356	The CIE Lab parameters	1335:1356	The CIE Lab parameters	1335:1356	The CIE Lab parameters and photoluminescence spectra were studied under visible light and ultraviolet irradiation.					
36239117	6	13	theme	photochromic	1055:1066	arg1	inks					1068:1071	The produced photochromic inks	1042:1071	The produced photochromic inks	1042:1071	The produced photochromic inks were spray-coated onto off-white paper sheets enclosing invisible fingermarks, and then exposed to thermofixation.					
36239117	3	14	theme	colorless	645:653	arg1	film					655:658	a fingerprinted colorless film	629:658	a fingerprinted colorless film onto cellulose documents with green emission	629:703	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	16	15	theme	Fluorescent	2134:2144	arg1	fingermark					2146:2155	Fluorescent fingermark	2134:2155	Fluorescent fingermark on paper sheets	2134:2171	Fluorescent fingermark on paper sheets demonstrated good photostability.					
36239117	8	16	theme	ultraviolet	1425:1435	arg1	irradiation					1437:1447	ultraviolet irradiation	1425:1447	ultraviolet irradiation	1425:1447	The CIE Lab parameters and photoluminescence spectra were studied under visible light and ultraviolet irradiation.					
36239117	13	17	theme	latent	1956:1961	arg1	analysis					1975:1982	latent fingerprint analysis	1956:1982	latent fingerprint analysis	1956:1982	Dual-mode fluorescent photochromism was presented for latent fingerprint analysis.					
36239117	1	18	theme	mapping	127:133	arg1	method					135:140	Simple and efficient detection and mapping method	92:140	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment	92:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	0	19	theme	fingermarks	79:89	arg1	mapping					68:74	mapping	68:74	mapping	68:74	Preparation of photoluminescent nanocomposite ink for detection and mapping of fingermarks.					
36239117	0	19	theme	fingermarks	79:89	arg1	detection					54:62	detection	54:62	detection	54:62	Preparation of photoluminescent nanocomposite ink for detection and mapping of fingermarks.					
36239117	1	20	theme	turn-on	160:166	arg1	pigment					180:186	a strong turn-on fluorescent pigment	151:186	a strong turn-on fluorescent pigment	151:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	6	21	theme	paper	1106:1110	arg1	sheets					1112:1117	off-white paper sheets	1096:1117	off-white paper sheets enclosing invisible fingermarks	1096:1149	The produced photochromic inks were spray-coated onto off-white paper sheets enclosing invisible fingermarks, and then exposed to thermofixation.					
36239117	2	22	theme	background	555:564	arg1	interference					566:577	background interference	555:577	background interference	555:577	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	13	23	theme	fluorescent	1912:1922	arg1	photochromism					1924:1936	Dual-mode fluorescent photochromism	1902:1936	Dual-mode fluorescent photochromism	1902:1936	Dual-mode fluorescent photochromism was presented for latent fingerprint analysis.					
36239117	4	24	theme	aluminate	863:871	arg1	PNPs					897:900	PNPs	897:900	PNPs; 27-49 nm	897:910	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	24	theme	aluminate	863:871	arg1	nanoparticles					882:894	rare-earth doped aluminate phosphor nanoparticles	846:894	rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent	846:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	12	25	theme	alkaline-earth	1841:1854	arg1	aluminate					1856:1864	alkaline-earth aluminate	1841:1864	alkaline-earth aluminate	1841:1864	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid was developed.					
36239117	10	26	theme	phosphor	1640:1647	arg1	particles					1649:1657	pigment phosphor particles	1632:1657	pigment phosphor particles	1632:1657	The morphologies of pigment phosphor particles and fingerprinted sheets were inspected.					
36239117	7	27	theme	UV	1325:1326	arg1	light					1328:1332	UV light	1325:1332	UV light	1325:1332	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	9	28	from	517 nm	1503:1508	arg1	band					1495:1498	fluorescence band	1482:1498	fluorescence band at 517 nm	1482:1508	The fingerprinted sheets showed fluorescence band at 517 nm upon excitation at 366 nm, showing a bathochromic shift and reversible photochromism without fatigue.					
36239117	2	29	theme	currency	400:407	arg1	notes					409:413	currency notes	400:413	currency notes characterized by optically changeable inks and highly fluorescent positions	400:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	9	30	theme	fluorescence	1482:1493	arg1	band					1495:1498	fluorescence band	1482:1498	fluorescence band at 517 nm	1482:1508	The fingerprinted sheets showed fluorescence band at 517 nm upon excitation at 366 nm, showing a bathochromic shift and reversible photochromism without fatigue.					
36239117	12	31	theme	Novel	1820:1824	arg1	ink					1832:1834	Novel smart ink	1820:1834	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid	1808:1885	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid was developed.					
36239117	10	32	theme	sheets	1677:1682	arg1	morphologies					1616:1627	The morphologies	1612:1627	The morphologies of pigment phosphor particles and fingerprinted sheets	1612:1682	The morphologies of pigment phosphor particles and fingerprinted sheets were inspected.					
36239117	4	33	theme	rare-earth	846:855	arg1	PNPs					897:900	PNPs	897:900	PNPs; 27-49 nm	897:910	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	33	theme	rare-earth	846:855	arg1	nanoparticles					882:894	rare-earth doped aluminate phosphor nanoparticles	846:894	rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent	846:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	0	34	theme	photoluminescent	15:30	arg1	Preparation					0:10	Preparation	0:10	Preparation of photoluminescent	0:30	Preparation of photoluminescent nanocomposite ink for detection and mapping of fingermarks.					
36239117	14	35	theme	color	2037:2041	arg1	change					2043:2048	color change	2037:2048	color change	2037:2048	Off-white fingerprinted films under daylight showed color change to green under UV.					
36239117	1	36	theme	detection	113:121	arg1	method					135:140	Simple and efficient detection and mapping method	92:140	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment	92:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	3	37	theme	green	690:694	arg1	emission					696:703	green emission	690:703	green emission	690:703	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	11	38	theme	samples	1785:1791	arg1	ink					1730:1732	ink	1730:1732	ink	1730:1732	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	11	38	theme	samples	1785:1791	arg1	behavior					1749:1756	mechanical behavior	1738:1756	mechanical behavior	1738:1756	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	11	39	theme	fingerprinted	1765:1777	arg1	samples					1785:1791	the fingerprinted paper samples	1761:1791	the fingerprinted paper samples	1761:1791	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	14	40	theme	Off-white	1985:1993	arg1	films					2009:2013	Off-white fingerprinted films	1985:2013	Off-white fingerprinted films under daylight	1985:2028	Off-white fingerprinted films under daylight showed color change to green under UV.					
36239117	16	41	theme	good	2186:2189	arg1	photostability					2191:2204	good photostability	2186:2204	good photostability	2186:2204	Fluorescent fingermark on paper sheets demonstrated good photostability.					
36239117	15	42	theme	Fluorescence	2069:2080	arg1	band					2082:2085	Fluorescence band	2069:2085	Fluorescence band	2069:2085	Fluorescence band monitored at 517 nm upon excitation at 366 nm.					
36239117	3	43	theme	photoluminescence	759:775	arg1	spectra					777:783	photoluminescence spectra	759:783	photoluminescence spectra	759:783	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	11	44	theme	ink	1730:1732	arg1	properties					1716:1725	The rheological properties	1700:1725	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples	1700:1791	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	3	45	theme	Novel	580:584	arg1	ink					599:601	Novel photochromic ink	580:601	Novel photochromic ink	580:601	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	9	46	theme	reversible	1570:1579	arg1	photochromism					1581:1593	reversible photochromism	1570:1593	reversible photochromism	1570:1593	The fingerprinted sheets showed fluorescence band at 517 nm upon excitation at 366 nm, showing a bathochromic shift and reversible photochromism without fatigue.					
36239117	5	47	theme	polyacrylic	995:1005	arg1	acid					1007:1010	polyacrylic acid	995:1010	polyacrylic acid	995:1010	PNPs were dispersed efficiently in polyacrylic acid to generate a colorless mark.					
36239117	1	48	theme	fluorescent	168:178	arg1	pigment					180:186	a strong turn-on fluorescent pigment	151:186	a strong turn-on fluorescent pigment	151:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	4	49	theme	polyacrylic	928:938	arg1	agent					953:957	a polyacrylic acid binding agent	926:957	a polyacrylic acid binding agent	926:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	13	50	theme	fingerprint	1963:1973	arg1	analysis					1975:1982	latent fingerprint analysis	1956:1982	latent fingerprint analysis	1956:1982	Dual-mode fluorescent photochromism was presented for latent fingerprint analysis.					
36239117	2	51	theme	fingerprint	324:334	arg1	detection					336:344	better fingerprint detection	317:344	better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions	317:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	4	52	dep	PNPs	897:900	arg1	27-49 nm					903:910	27-49 nm	903:910	PNPs; 27-49 nm	897:910	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	53	theme	binding	945:951	arg1	agent					953:957	a polyacrylic acid binding agent	926:957	a polyacrylic acid binding agent	926:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	7	54	theme	Photochromic	1188:1199	arg1	film					1201:1204	Photochromic film	1188:1204	Photochromic film	1188:1204	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	11	55	theme	mechanical	1738:1747	arg1	behavior					1749:1756	mechanical behavior	1738:1756	mechanical behavior	1738:1756	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	3	56	theme	fingerprinted	631:643	arg1	film					655:658	a fingerprinted colorless film	629:658	a fingerprinted colorless film onto cellulose documents with green emission	629:703	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	3	57	dep	cellulose	665:673	arg1	documents					675:683	documents	675:683	documents	675:683	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	6	58	theme	produced	1046:1053	arg1	inks					1068:1071	The produced photochromic inks	1042:1071	The produced photochromic inks	1042:1071	The produced photochromic inks were spray-coated onto off-white paper sheets enclosing invisible fingermarks, and then exposed to thermofixation.					
36239117	2	59	theme	interference	566:577	arg1	difficulty					541:550	the difficulty	537:550	the difficulty of background interference	537:577	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	8	60	theme	visible	1407:1413	arg1	light					1415:1419	visible light	1407:1419	visible light	1407:1419	The CIE Lab parameters and photoluminescence spectra were studied under visible light and ultraviolet irradiation.					
36239117	8	61	theme	Lab	1343:1345	arg1	parameters					1347:1356	The CIE Lab parameters	1335:1356	The CIE Lab parameters	1335:1356	The CIE Lab parameters and photoluminescence spectra were studied under visible light and ultraviolet irradiation.					
36239117	4	62	theme	Inorganic/organic	786:802	arg1	ink					824:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	2	63	theme	strong	274:279	arg1	emission					281:288	strong emission	274:288	strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast	274:524	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	4	64	theme	composite	814:822	arg1	ink					824:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink	786:826	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	7	65	located	detected	1210:1217	arg2	film					1201:1204	Photochromic film	1188:1204	Photochromic film	1188:1204	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	7	65	located	detected	1210:1217	arg1	surface					1228:1234	paper surface	1222:1234	paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light	1222:1332	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	3	66	with	film	655:658	arg1	emission					696:703	green emission	690:703	green emission	690:703	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	6	67	theme	invisible	1129:1137	arg1	fingermarks					1139:1149	invisible fingermarks	1129:1149	invisible fingermarks	1129:1149	The produced photochromic inks were spray-coated onto off-white paper sheets enclosing invisible fingermarks, and then exposed to thermofixation.					
36239117	1	68	theme	strong	153:158	arg1	pigment					180:186	a strong turn-on fluorescent pigment	151:186	a strong turn-on fluorescent pigment	151:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	12	69	theme	polyacrylic	1870:1880	arg1	acid					1882:1885	polyacrylic acid	1870:1885	polyacrylic acid	1870:1885	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid was developed.					
36239117	2	70	theme	better	510:515	arg1	contrast					517:524	better contrast	510:524	better contrast	510:524	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	13	71	theme	Dual-mode	1902:1910	arg1	photochromism					1924:1936	Dual-mode fluorescent photochromism	1902:1936	Dual-mode fluorescent photochromism	1902:1936	Dual-mode fluorescent photochromism was presented for latent fingerprint analysis.					
36239117	6	72	theme	off-white	1096:1104	arg1	sheets					1112:1117	off-white paper sheets	1096:1117	off-white paper sheets enclosing invisible fingermarks	1096:1149	The produced photochromic inks were spray-coated onto off-white paper sheets enclosing invisible fingermarks, and then exposed to thermofixation.					
36239117	5	73	dep	colorless	1026:1034	arg1	mark					1036:1039	mark	1036:1039	mark	1036:1039	PNPs were dispersed efficiently in polyacrylic acid to generate a colorless mark.					
36239117	4	74	theme	doped	857:861	arg1	PNPs					897:900	PNPs	897:900	PNPs; 27-49 nm	897:910	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	74	theme	doped	857:861	arg1	nanoparticles					882:894	rare-earth doped aluminate phosphor nanoparticles	846:894	rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent	846:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	9	75	theme	fingerprinted	1454:1466	arg1	sheets					1468:1473	The fingerprinted sheets	1450:1473	The fingerprinted sheets	1450:1473	The fingerprinted sheets showed fluorescence band at 517 nm upon excitation at 366 nm, showing a bathochromic shift and reversible photochromism without fatigue.					
36239117	10	76	theme	pigment	1632:1638	arg1	particles					1649:1657	pigment phosphor particles	1632:1657	pigment phosphor particles	1632:1657	The morphologies of pigment phosphor particles and fingerprinted sheets were inspected.					
36239117	4	77	theme	phosphor	873:880	arg1	PNPs					897:900	PNPs	897:900	PNPs; 27-49 nm	897:910	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	4	77	theme	phosphor	873:880	arg1	nanoparticles					882:894	rare-earth doped aluminate phosphor nanoparticles	846:894	rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent	846:957	Inorganic/organic nanoscale composite ink was prepared from rare-earth doped aluminate phosphor nanoparticles (PNPs; 27-49 nm) dispersed in a polyacrylic acid binding agent.					
36239117	1	78	theme	Simple	92:97	arg1	method					135:140	Simple and efficient detection and mapping method	92:140	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment	92:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	2	79	theme	fluorescent	469:479	arg1	positions					481:489	highly fluorescent positions	462:489	highly fluorescent positions	462:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	1	80	theme	efficient	103:111	arg1	method					135:140	Simple and efficient detection and mapping method	92:140	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment	92:186	Simple and efficient detection and mapping method based on a strong turn-on fluorescent pigment was developed for fingerprint analysis.					
36239117	2	81	theme	phosphor	241:248	arg1	powder					250:255	a phosphor powder	239:255	a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast	239:524	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	10	82	theme	fingerprinted	1663:1675	arg1	sheets					1677:1682	fingerprinted sheets	1663:1682	fingerprinted sheets	1663:1682	The morphologies of pigment phosphor particles and fingerprinted sheets were inspected.					
36239117	2	83	theme	changeable	442:451	arg1	inks					453:456	optically changeable inks	432:456	optically changeable inks	432:456	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	7	84	theme	visible	1278:1284	arg1	daylight					1286:1293	visible daylight	1278:1293	visible daylight	1278:1293	Photochromic film was detected on paper surface presenting a transparent appearance under visible daylight and switchable to green under UV light.					
36239117	16	85	theme	paper	2160:2164	arg1	sheets					2166:2171	paper sheets	2160:2171	paper sheets	2160:2171	Fluorescent fingermark on paper sheets demonstrated good photostability.					
36239117	12	86	theme	smart	1826:1830	arg1	ink					1832:1834	Novel smart ink	1820:1834	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid	1808:1885	HIGHLIGHTS: Novel smart ink with alkaline-earth aluminate and polyacrylic acid was developed.					
36239117	10	87	theme	particles	1649:1657	arg1	morphologies					1616:1627	The morphologies	1612:1627	The morphologies of pigment phosphor particles and fingerprinted sheets	1612:1682	The morphologies of pigment phosphor particles and fingerprinted sheets were inspected.					
36239117	11	88	theme	paper	1779:1783	arg1	samples					1785:1791	the fingerprinted paper samples	1761:1791	the fingerprinted paper samples	1761:1791	The rheological properties of ink and mechanical behavior of the fingerprinted paper samples were explored.					
36239117	2	89	theme	multicolored	349:360	arg1	notes					409:413	currency notes	400:413	currency notes characterized by optically changeable inks and highly fluorescent positions	400:489	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	2	89	theme	multicolored	349:360	arg1	surfaces					382:389	multicolored or photoluminescent surfaces	349:389	multicolored or photoluminescent surfaces	349:389	We present a phosphor powder characterized by strong emission which is useful to achieve better fingerprint detection on multicolored or photoluminescent surfaces, such as currency notes characterized by optically changeable inks and highly fluorescent positions, because it offers better contrast and reduce the difficulty of background interference.					
36239117	14	90	theme	fingerprinted	1995:2007	arg1	films					2009:2013	Off-white fingerprinted films	1985:2013	Off-white fingerprinted films under daylight	1985:2028	Off-white fingerprinted films under daylight showed color change to green under UV.					
36239117	3	91	theme	anticounterfeiting	709:726	arg1	applications					728:739	anticounterfeiting applications	709:739	anticounterfeiting applications	709:739	Novel photochromic ink was prepared to establish a fingerprinted colorless film onto cellulose documents with green emission for anticounterfeiting applications as illustrated by photoluminescence spectra.					
36239117	16	92	from	fingermark	2146:2155	arg1	sheets					2166:2171	paper sheets	2160:2171	paper sheets	2160:2171	Fluorescent fingermark on paper sheets demonstrated good photostability.					
36239117	9	93	theme	bathochromic	1547:1558	arg1	shift					1560:1564	a bathochromic shift	1545:1564	a bathochromic shift	1545:1564	The fingerprinted sheets showed fluorescence band at 517 nm upon excitation at 366 nm, showing a bathochromic shift and reversible photochromism without fatigue.					
35450634	0	0	theme	composite	73:81	arg1	hydrogels					83:91	nanofiber composite hydrogels	63:91	nanofiber composite hydrogels	63:91	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	7	1	theme	interesting	1129:1139	arg1	method					1141:1146	an interesting method	1126:1146	an interesting method of probing networks	1126:1166	This work proposes an interesting method of probing networks in the multiply cross-linked hydrogels.					
35450634	1	2	theme	networks	156:163	arg1	roles					137:141	the roles	133:141	the roles of different networks in the multiply cross-linked hydrogels	133:202	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	0	3	theme	nanofiber	63:71	arg1	hydrogels					83:91	nanofiber composite hydrogels	63:91	nanofiber composite hydrogels	63:91	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	6	4	theme	work	1101:1104	arg1	behavior					1078:1085	the scaling behavior	1066:1085	the scaling behavior of hysteretic work	1066:1104	Their synergistic effect can be well defined by the scaling behavior of hysteretic work.					
35450634	4	5	theme	strain-induced	806:819	arg1	one					821:823	strain-induced one	806:823	strain-induced one	806:823	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	2	6	theme	composite	292:300	arg1	template					325:332	template	325:332	template	325:332	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	6	theme	composite	292:300	arg1	hydrogels					302:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	7	theme	nanofiber	282:290	arg1	template					325:332	template	325:332	template	325:332	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	7	theme	nanofiber	282:290	arg1	hydrogels					302:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	4	8	theme	stress-induced	731:744	arg1	deformation					746:756	stress-induced deformation	731:756	stress-induced deformation	731:756	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	1	9	link	cross-linked	181:192	arg1	hydrogels					194:202	the multiply cross-linked hydrogels	168:202	the multiply cross-linked hydrogels	168:202	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	6	10	theme	hysteretic	1090:1099	arg1	work					1101:1104	hysteretic work	1090:1104	hysteretic work	1090:1104	Their synergistic effect can be well defined by the scaling behavior of hysteretic work.					
35450634	2	11	theme	/cellulose	271:280	arg1	template					325:332	template	325:332	template	325:332	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	11	theme	/cellulose	271:280	arg1	hydrogels					302:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	3	12	theme	boronic	434:440	arg1	bonds					448:452	boronic ester bonds	434:452	boronic ester bonds	434:452	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	5	13	theme	higher	880:885	arg1	level					887:891	higher level	880:891	higher level of elastic storage	880:910	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	0	14	theme	viscoelastic	97:108	arg1	probes					110:115	viscoelastic probes	97:115	viscoelastic probes	97:115	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	4	15	theme	sensitive	793:801	arg1	network					780:786	the chemical network	767:786	the chemical network more sensitive to strain-induced one	767:823	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	0	16	theme	hierarchical	8:19	arg1	networks					21:28	Mapping hierarchical networks	0:28	Mapping hierarchical networks of poly(vinyl alcohol)	0:51	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	3	17	theme	networks	538:545	arg1	network					408:414	chemical network	399:414	chemical network cross-linked with boronic ester bonds	399:452	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	17	theme	networks	538:545	arg1	coexistence					513:523	coexistence	513:523	coexistence of these two networks	513:545	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	17	theme	networks	538:545	arg1	network					464:470	physical network	455:470	physical network cross-linked with microcrystallites	455:506	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	1	18	from	roles	137:141	arg1	hydrogels					194:202	the multiply cross-linked hydrogels	168:202	the multiply cross-linked hydrogels	168:202	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	7	19	theme	cross-linked	1184:1195	arg1	hydrogels					1197:1205	the multiply cross-linked hydrogels	1171:1205	the multiply cross-linked hydrogels	1171:1205	This work proposes an interesting method of probing networks in the multiply cross-linked hydrogels.					
35450634	1	20	theme	cross-linked	181:192	arg1	hydrogels					194:202	the multiply cross-linked hydrogels	168:202	the multiply cross-linked hydrogels	168:202	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	0	21	theme	Mapping	0:6	arg1	networks					21:28	Mapping hierarchical networks	0:28	Mapping hierarchical networks of poly(vinyl alcohol)	0:51	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	5	22	theme	linear	953:958	arg1	viscoelasticity					960:974	linear viscoelasticity	953:974	linear viscoelasticity of hydrogels	953:987	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	3	23	theme	ester	442:446	arg1	bonds					448:452	boronic ester bonds	434:452	boronic ester bonds	434:452	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	24	theme	characteristic	364:377	arg1	networks					379:386	characteristic networks	364:386	characteristic networks	364:386	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	4	25	theme	chemical	771:778	arg1	network					780:786	the chemical network	767:786	the chemical network more sensitive to strain-induced one	767:823	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	5	26	theme	hydrogels	979:987	arg1	viscoelasticity					960:974	linear viscoelasticity	953:974	linear viscoelasticity of hydrogels	953:987	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	3	27	theme	networks	379:386	arg1	network					464:470	physical network	455:470	physical network cross-linked with microcrystallites	455:506	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	27	theme	networks	379:386	arg1	coexistence					513:523	coexistence	513:523	coexistence of these two networks	513:545	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	27	theme	networks	379:386	arg1	types					355:359	Three types	349:359	Three types	349:359	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	27	theme	networks	379:386	arg1	network					408:414	chemical network	399:414	chemical network cross-linked with boronic ester bonds	399:452	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	5	28	theme	viscous	856:862	arg1	dissipation					864:874	viscous dissipation	856:874	viscous dissipation	856:874	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	7	29	theme	networks	1159:1166	arg1	method					1141:1146	an interesting method	1126:1146	an interesting method of probing networks	1126:1166	This work proposes an interesting method of probing networks in the multiply cross-linked hydrogels.					
35450634	5	30	theme	dissipation	864:874	arg1	level					887:891	higher level	880:891	higher level of elastic storage	880:910	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	5	30	theme	dissipation	864:874	arg1	level					847:851	lower level	841:851	lower level of viscous dissipation	841:874	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	5	31	theme	elastic	896:902	arg1	storage					904:910	elastic storage	896:910	elastic storage	896:910	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	3	32	theme	physical	455:462	arg1	network					464:470	physical network	455:470	physical network cross-linked with microcrystallites	455:506	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	0	33	theme	poly	33:36	arg1	networks					21:28	Mapping hierarchical networks	0:28	Mapping hierarchical networks of poly(vinyl alcohol)	0:51	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	3	34	theme	characteristic	635:648	arg1	behavior					661:668	the characteristic relaxation behavior	631:668	the characteristic relaxation behavior of those networks	631:686	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	5	35	theme	lower	841:845	arg1	level					847:851	lower level	841:851	lower level of viscous dissipation	841:874	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	3	36	theme	chemical	399:406	arg1	network					408:414	chemical network	399:414	chemical network cross-linked with boronic ester bonds	399:452	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	3	37	theme	relaxation	650:659	arg1	behavior					661:668	the characteristic relaxation behavior	631:668	the characteristic relaxation behavior of those networks	631:686	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	0	38	theme	vinyl	38:42	arg1	poly					33:36	poly	33:36	poly(vinyl alcohol)	33:51	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	0	38	theme	vinyl	38:42	arg1	alcohol					44:50	vinyl alcohol	38:50	vinyl alcohol	38:50	Mapping hierarchical networks of poly(vinyl alcohol)/cellulose nanofiber composite hydrogels via viscoelastic probes.					
35450634	6	39	theme	scaling	1070:1076	arg1	behavior					1078:1085	the scaling behavior	1066:1085	the scaling behavior of hysteretic work	1066:1104	Their synergistic effect can be well defined by the scaling behavior of hysteretic work.					
35450634	3	40	theme	viscoelastic	588:599	arg1	responses					601:609	the viscoelastic responses	584:609	the viscoelastic responses	584:609	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	5	41	contain	has	837:839	arg2	level					847:851	lower level	841:851	lower level of viscous dissipation	841:874	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	5	41	contain	has	837:839	arg2	level					887:891	higher level	880:891	higher level of elastic storage	880:910	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	5	41	contain	has	837:839	arg1	former					830:835	former	830:835	former	830:835	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	7	42	theme	probing	1151:1157	arg1	networks					1159:1166	probing networks	1151:1166	probing networks	1151:1166	This work proposes an interesting method of probing networks in the multiply cross-linked hydrogels.					
35450634	4	43	theme	physical	693:700	arg1	network					702:708	The physical network	689:708	The physical network	689:708	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	4	43	theme	physical	693:700	arg1	sensitive					718:726	sensitive	718:726	sensitive	718:726	The physical network is more sensitive to stress-induced deformation, whereas the chemical network more sensitive to strain-induced one.					
35450634	2	44	theme	vinyl	257:261	arg1	Poly					252:255	Poly	252:255	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	44	theme	vinyl	257:261	arg1	alcohol					263:269	vinyl alcohol	257:269	vinyl alcohol	257:269	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	1	45	theme	different	146:154	arg1	networks					156:163	different networks	146:163	different networks	146:163	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	2	46	used	used	317:320	arg2	template					325:332	template	325:332	template	325:332	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	46	used	used	317:320	arg2	hydrogels					302:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	1	47	theme	overall	231:237	arg1	performance					239:249	their overall performance	225:249	their overall performance	225:249	Discriminating the roles of different networks in the multiply cross-linked hydrogels is vital to optimize their overall performance.					
35450634	3	48	theme	networks	679:686	arg1	behavior					661:668	the characteristic relaxation behavior	631:668	the characteristic relaxation behavior of those networks	631:686	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	7	49	link	cross-linked	1184:1195	arg1	hydrogels					1197:1205	the multiply cross-linked hydrogels	1171:1205	the multiply cross-linked hydrogels	1171:1205	This work proposes an interesting method of probing networks in the multiply cross-linked hydrogels.					
35450634	5	50	theme	storage	904:910	arg1	level					887:891	higher level	880:891	higher level of elastic storage	880:910	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	5	50	theme	storage	904:910	arg1	level					847:851	lower level	841:851	lower level of viscous dissipation	841:874	The former has lower level of viscous dissipation and higher level of elastic storage as compared to the latter, and dominates linear viscoelasticity of hydrogels as the two networks coexist.					
35450634	2	51	theme	Poly	252:255	arg1	template					325:332	template	325:332	template	325:332	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	2	51	theme	Poly	252:255	arg1	hydrogels					302:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels	252:310	Poly(vinyl alcohol)/cellulose nanofiber composite hydrogels were used as template for the study.					
35450634	3	52	used	used	616:619	arg2	responses					601:609	the viscoelastic responses	584:609	the viscoelastic responses	584:609	Three types of characteristic networks, including chemical network cross-linked with boronic ester bonds, physical network cross-linked with microcrystallites, and coexistence of these two networks, were constructed in the system, and the viscoelastic responses were used to detect the characteristic relaxation behavior of those networks.					
35450634	6	53	theme	synergistic	1024:1034	arg1	effect					1036:1041	Their synergistic effect	1018:1041	Their synergistic effect	1018:1041	Their synergistic effect can be well defined by the scaling behavior of hysteretic work.					
37236573	5	0	theme	coral	1358:1362	arg1	soils					1369:1373	coral sand soils	1358:1373	coral sand soils	1358:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	5	1	theme	plant	1245:1249	arg1	development					1251:1261	plant development	1245:1261	plant development	1245:1261	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	4	2	theme	AA-co-AM	977:984	arg1	/PVA					986:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	3	theme	rapid	183:187	arg1	capacity					200:207	the rapid absorption capacity	179:207	the rapid absorption capacity of coral sand soil for rainfall	179:239	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	2	4	theme	AA-co-AM	516:523	arg1	/PVA					525:528	CMC-g-P (AA-co-AM)/PVA	507:528	CMC-g-P (AA-co-AM)/PVA	507:528	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	4	5	theme	2 wt	962:965	arg1	/PVA					986:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	2	6	theme	CMC-g-P	507:513	arg1	/PVA					525:528	CMC-g-P (AA-co-AM)/PVA	507:528	CMC-g-P (AA-co-AM)/PVA	507:528	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	4	7	theme	CMC-g-P	968:974	arg1	/PVA					986:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	8	theme	coral	212:216	arg1	soil					223:226	coral sand soil	212:226	coral sand soil	212:226	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	2	9	theme	distilled	533:541	arg1	water					543:547	distilled water	533:547	distilled water in 1 h	533:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	0	10	theme	coral	151:155	arg1	soil					162:165	coral sand soil	151:165	coral sand soil	151:165	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	3	11	theme	AA-co-AM	758:765	arg1	/PVA					767:770	CMC-g-P (AA-co-AM)/PVA	749:770	CMC-g-P (AA-co-AM)/PVA	749:770	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	2	12	theme	/PVA	525:528	arg1	26.45 g/g					560:568	26.45 g/g	560:568	26.45 g/g	560:568	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	2	12	theme	/PVA	525:528	arg1	absorption					493:502	the rapid water absorption	477:502	the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h	477:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	3	13	from	29.5	784:787	arg1	solutions					828:836	0.9 wt% NaCl and CaCl2 solutions	805:836	0.9 wt% NaCl and CaCl2 solutions	805:836	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	4	14	theme	coral	1028:1032	arg1	sand					1034:1037	the coral sand	1024:1037	the coral sand	1024:1037	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	15	theme	CMC-g-P	407:413	arg1	granules					425:432	coupling CMC-g-P(AA-co-AM) granules	398:432	coupling CMC-g-P(AA-co-AM) granules with a PVA sponge	398:450	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	16	theme	CMC-g-P	749:755	arg1	/PVA					767:770	CMC-g-P (AA-co-AM)/PVA	749:770	CMC-g-P (AA-co-AM)/PVA	749:770	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	2	17	theme	short-term	645:654	arg1	rainfall					656:663	short-term rainfall	645:663	short-term rainfall	645:663	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	3	18	theme	slight	696:701	arg1	influence					703:711	a slight influence	694:711	a slight influence	694:711	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	0	19	theme	/polyvinyl	72:81	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	1	20	theme	sponge	335:340	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	20	theme	sponge	335:340	arg1	composite					244:252	a composite	242:252	a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	242:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	4	21	theme	interception	1002:1013	arg1	ratio					1015:1019	the water interception ratio	992:1019	the water interception ratio of the coral sand	992:1037	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	0	22	theme	sponge	91:96	arg1	application					136:146	its application	132:146	its application in coral sand soil	132:165	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	0	22	theme	sponge	91:96	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	0:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	1	23	theme	CMC-g-P	343:349	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	23	theme	CMC-g-P	343:349	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	24	theme	/PVA	767:770	arg1	capacity					737:744	the water absorption capacity	716:744	the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively	716:850	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	0	25	from	Synthesis	0:8	arg1	soil					162:165	coral sand soil	151:165	coral sand soil	151:165	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	5	26	theme	CMC-g-P	1301:1307	arg1	/PVA					1319:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	5	26	theme	CMC-g-P	1301:1307	arg1	amendment					1344:1352	a promising soil amendment	1327:1352	a promising soil amendment for coral sand soils	1327:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	3	27	theme	water	720:724	arg1	capacity					737:744	the water absorption capacity	716:744	the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively	716:850	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	1	28	theme	AA-co-AM	351:358	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	28	theme	AA-co-AM	351:358	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	29	theme	coral	929:933	arg1	sand					935:938	high‑calcium coral sand	916:938	high‑calcium coral sand	916:938	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	2	30	theme	rapid	481:485	arg1	26.45 g/g					560:568	26.45 g/g	560:568	26.45 g/g	560:568	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	2	30	theme	rapid	481:485	arg1	absorption					493:502	the rapid water absorption	477:502	the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h	477:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	0	31	theme	absorbent	108:116	arg1	composite					118:126	a fast absorbent composite	101:126	a fast absorbent composite	101:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	5	32	theme	pot	1160:1162	arg1	experiments					1164:1174	pot experiments	1160:1174	pot experiments	1160:1174	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	1	33	theme	carboxymethyl	257:269	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	33	theme	carboxymethyl	257:269	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	34	theme	NaCl	813:816	arg1	solutions					828:836	0.9 wt% NaCl and CaCl2 solutions	805:836	0.9 wt% NaCl and CaCl2 solutions	805:836	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	2	35	from	water	543:547	arg1	1 h					552:554	1 h	552:554	1 h	552:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	4	36	theme	13.8 	1054:1058	arg1	%					1059:1059	%	1059:1059	%	1059:1059	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	0	37	theme	carboxymethyl	13:25	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	3	38	theme	0.9 wt	805:810	arg1	NaCl					813:816	0.9 wt% NaCl	805:816	0.9 wt% NaCl	805:816	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	5	39	theme	soil	1339:1342	arg1	/PVA					1319:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	5	39	theme	soil	1339:1342	arg1	amendment					1344:1352	a promising soil amendment	1327:1352	a promising soil amendment for coral sand soils	1327:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	1	40	theme	acid-co-acrylamide	297:314	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	40	theme	acid-co-acrylamide	297:314	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	5	41	theme	AA-co-AM	1310:1317	arg1	/PVA					1319:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	5	41	theme	AA-co-AM	1310:1317	arg1	amendment					1344:1352	a promising soil amendment	1327:1352	a promising soil amendment for coral sand soils	1327:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	4	42	theme	interception	1096:1107	arg1	water					1109:1113	the total interception water	1086:1113	the total interception water	1086:1113	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	5	43	theme	CMC-g-P	1200:1206	arg1	/PVA					1217:1220	2 wt% CMC-g-P(AA-co-AM)/PVA	1194:1220	2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand	1194:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	0	44	theme	acid-co-acrylamide	53:70	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	1	45	theme	/polyvinyl	316:325	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	45	theme	/polyvinyl	316:325	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	46	theme	CaCl2	822:826	arg1	solutions					828:836	0.9 wt% NaCl and CaCl2 solutions	805:836	0.9 wt% NaCl and CaCl2 solutions	805:836	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	5	47	theme	AA-co-AM	1208:1215	arg1	/PVA					1217:1220	2 wt% CMC-g-P(AA-co-AM)/PVA	1194:1220	2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand	1194:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	1	48	theme	sand	218:221	arg1	soil					223:226	coral sand soil	212:226	coral sand soil	212:226	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	5	49	from	/PVA	1217:1220	arg1	sand					1231:1234	coral sand	1225:1234	coral sand	1225:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	0	50	from	application	136:146	arg1	soil					162:165	coral sand soil	151:165	coral sand soil	151:165	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	5	51	theme	2 wt	1194:1197	arg1	/PVA					1217:1220	2 wt% CMC-g-P(AA-co-AM)/PVA	1194:1220	2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand	1194:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	3	52	theme	CMC-g-P	890:896	arg1	/PVA					908:911	CMC-g-P (AA-co-AM)/PVA	890:911	CMC-g-P (AA-co-AM)/PVA	890:911	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	5	53	theme	sand	1364:1367	arg1	soils					1369:1373	coral sand soils	1358:1373	coral sand soils	1358:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	3	54	theme	/PVA	908:911	arg1	adaptability					874:885	the great adaptability	864:885	the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand	864:938	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	4	55	theme	15-day	1130:1135	arg1	evaporation					1137:1147	15-day evaporation	1130:1147	15-day evaporation	1130:1147	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	56	theme	PVA	441:443	arg1	sponge					445:450	a PVA sponge	439:450	a PVA sponge	439:450	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	57	theme	AA-co-AM	899:906	arg1	/PVA					908:911	CMC-g-P (AA-co-AM)/PVA	890:911	CMC-g-P (AA-co-AM)/PVA	890:911	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	4	58	theme	%	966:966	arg1	/PVA					986:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	2 wt% CMC-g-P (AA-co-AM)/PVA	962:989	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	5	59	theme	coral	1225:1229	arg1	sand					1231:1234	coral sand	1225:1234	coral sand	1225:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	1	60	theme	absorption	189:198	arg1	capacity					200:207	the rapid absorption capacity	179:207	the rapid absorption capacity of coral sand soil for rainfall	179:239	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	0	61	theme	sand	157:160	arg1	soil					162:165	coral sand soil	151:165	coral sand soil	151:165	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	4	62	theme	sand	1034:1037	arg1	ratio					1015:1019	the water interception ratio	992:1019	the water interception ratio of the coral sand	992:1037	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	63	theme	coupling	398:405	arg1	AA-co-AM					415:422	AA-co-AM	415:422	AA-co-AM	415:422	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	63	theme	coupling	398:405	arg1	CMC-g-P					407:413	coupling CMC-g-P	398:413	coupling CMC-g-P(AA-co-AM) granules with a PVA sponge	398:450	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	2	64	from	absorption	493:502	arg1	water					543:547	distilled water	533:547	distilled water in 1 h	533:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	4	65	theme	water	996:1000	arg1	ratio					1015:1019	the water interception ratio	992:1019	the water interception ratio of the coral sand	992:1037	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	0	66	theme	alcohol	83:89	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	4	67	dep	/PVA	986:989	arg1	the					946:948	the	946:948	the	946:948	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	4	67	dep	/PVA	986:989	arg1	addition					950:957	addition	950:957	addition	950:957	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	4	68	theme	23.7 	1064:1068	arg1	%					1059:1059	%	1059:1059	%	1059:1059	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	0	69	theme	fast	103:106	arg1	composite					118:126	a fast absorbent composite	101:126	a fast absorbent composite	101:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	3	70	theme	high‑calcium	916:927	arg1	sand					935:938	high‑calcium coral sand	916:938	high‑calcium coral sand	916:938	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	2	71	theme	water	487:491	arg1	26.45 g/g					560:568	26.45 g/g	560:568	26.45 g/g	560:568	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	2	71	theme	water	487:491	arg1	absorption					493:502	the rapid water absorption	477:502	the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h	477:554	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	3	72	theme	absorption	726:735	arg1	capacity					737:744	the water absorption capacity	716:744	the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively	716:850	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	5	73	theme	water	1269:1273	arg1	scarcity					1275:1282	water scarcity	1269:1282	water scarcity	1269:1282	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	2	74	theme	PVA	611:613	arg1	sponge					615:620	the PVA sponge	607:620	the PVA sponge	607:620	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	2	74	theme	PVA	611:613	arg1	suitable					632:639	suitable	632:639	suitable	632:639	The results showed that the rapid water absorption of CMC-g-P (AA-co-AM)/PVA in distilled water in 1 h was 26.45 g/g, twice that of CMC-g-P(AA-co-AM) and the PVA sponge, which is suitable for short-term rainfall.					
37236573	3	75	contain	had	690:692	arg1	cation					683:688	the cation	679:688	the cation	679:688	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	3	75	contain	had	690:692	arg2	influence					703:711	a slight influence	694:711	a slight influence	694:711	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	0	76	theme	cellulose-g-poly	27:42	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	1	77	theme	cellulose-g-poly	271:286	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	77	theme	cellulose-g-poly	271:286	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	5	78	theme	promising	1329:1337	arg1	/PVA					1319:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	CMC-g-P (AA-co-AM)/PVA	1301:1322	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	5	78	theme	promising	1329:1337	arg1	amendment					1344:1352	a promising soil amendment	1327:1352	a promising soil amendment for coral sand soils	1327:1373	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	4	79	theme	total	1090:1094	arg1	water					1109:1113	the total interception water	1086:1113	the total interception water	1086:1113	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	0	80	theme	acrylic	45:51	arg1	sponge					91:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	13:96	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite	13:126	Synthesis of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge as a fast absorbent composite and its application in coral sand soil.					
37236573	1	81	theme	acrylic	289:295	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	81	theme	acrylic	289:295	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	82	theme	%	811:811	arg1	NaCl					813:816	0.9 wt% NaCl	805:816	0.9 wt% NaCl	805:816	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
37236573	1	83	with	granules	425:432	arg1	sponge					445:450	a PVA sponge	439:450	a PVA sponge	439:450	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	4	84	theme	water	1109:1113	arg1	%					1081:1081	54.6 %	1076:1081	54.6 % of the total interception water	1076:1113	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	4	84	theme	water	1109:1113	arg1	water					1109:1113	the total interception water	1086:1113	the total interception water	1086:1113	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	5	85	theme	%	1198:1198	arg1	/PVA					1217:1220	2 wt% CMC-g-P(AA-co-AM)/PVA	1194:1220	2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand	1194:1234	Moreover, pot experiments demonstrated that 2 wt% CMC-g-P(AA-co-AM)/PVA in coral sand enhanced plant development under water scarcity, suggesting that CMC-g-P (AA-co-AM)/PVA is a promising soil amendment for coral sand soils.					
37236573	4	86	dep	%	1059:1059	arg1	to					1061:1062	to	1061:1062	to	1061:1062	With the addition of 2 wt% CMC-g-P (AA-co-AM)/PVA, the water interception ratio of the coral sand increased from 13.8 % to 23.7 %, and 54.6 % of the total interception water remained after 15-day evaporation.					
37236573	1	87	theme	alcohol	327:333	arg1	sponge					335:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge	257:340	carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA)	257:364	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	87	theme	alcohol	327:333	arg1	/PVA					360:363	CMC-g-P(AA-co-AM)/PVA	343:363	CMC-g-P(AA-co-AM)/PVA	343:363	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	1	88	theme	soil	223:226	arg1	capacity					200:207	the rapid absorption capacity	179:207	the rapid absorption capacity of coral sand soil for rainfall	179:239	To improve the rapid absorption capacity of coral sand soil for rainfall, a composite of carboxymethyl cellulose-g-poly (acrylic acid-co-acrylamide)/polyvinyl alcohol sponge (CMC-g-P(AA-co-AM)/PVA) was designed and synthesized by coupling CMC-g-P(AA-co-AM) granules with a PVA sponge.					
37236573	3	89	theme	great	868:872	arg1	adaptability					874:885	the great adaptability	864:885	the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand	864:938	In addition, the cation had a slight influence on the water absorption capacity of CMC-g-P (AA-co-AM)/PVA, which were 29.5 and 18.9 g/g in 0.9 wt% NaCl and CaCl2 solutions, respectively, indicating the great adaptability of CMC-g-P (AA-co-AM)/PVA to high‑calcium coral sand.					
36008982	8	0	theme	photothermal	1114:1125	arg1	efficiency					1138:1147	a photothermal conversion efficiency	1112:1147	a photothermal conversion efficiency of 23.7%	1112:1156	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	4	1	theme	oxidized	551:558	arg1	dextran					560:566	oxidized dextran	551:566	oxidized dextran	551:566	Polyaniline was firstly grafted onto chitosan and its solution was mixed with oxidized dextran, which was then cross-linked into a hydrogel via a Schiff base reaction.					
36008982	7	2	theme	photothermal	966:977	arg1	properties					990:999	good photothermal conversion properties	961:999	good photothermal conversion properties	961:999	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	1	3	theme	attention	177:185	arg1	deal					169:172	a great deal	161:172	a great deal of attention	161:185	In recent years, multifunctional hydrogels have received a great deal of attention because they are biocompatible and can mimic the extracellular matrix.					
36008982	4	4	theme	base	626:629	arg1	reaction					631:638	a Schiff base reaction	617:638	a Schiff base reaction	617:638	Polyaniline was firstly grafted onto chitosan and its solution was mixed with oxidized dextran, which was then cross-linked into a hydrogel via a Schiff base reaction.					
36008982	4	5	theme	Schiff	619:624	arg1	reaction					631:638	a Schiff base reaction	617:638	a Schiff base reaction	617:638	Polyaniline was firstly grafted onto chitosan and its solution was mixed with oxidized dextran, which was then cross-linked into a hydrogel via a Schiff base reaction.					
36008982	3	6	theme	COL	405:407	arg1	hydrogel					410:417	a chitosan/polyaniline/laponite (COL) hydrogel	372:417	a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability	372:457	In this study, a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability was designed.					
36008982	9	7	theme	COL	1281:1283	arg1	hydrogel					1285:1292	the COL hydrogel	1277:1292	the COL hydrogel	1277:1292	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	7	8	theme	conversion	979:988	arg1	properties					990:999	good photothermal conversion properties	961:999	good photothermal conversion properties	961:999	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	2	9	theme	networks	318:325	arg1	hydrogels					278:286	hydrogels	278:286	hydrogels of biocompatible cross-linked networks with photothermal properties	278:354	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	6	10	theme	swelling	744:751	arg1	ratio					753:757	The swelling ratio	740:757	The swelling ratio of the COL hydrogel in various solutions	740:798	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	6	10	theme	swelling	744:751	arg1	%					820:820	greater than 580%	804:820	greater than 580%	804:820	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	3	11	theme	chitosan/polyaniline/laponite	374:402	arg1	hydrogel					410:417	a chitosan/polyaniline/laponite (COL) hydrogel	372:417	a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability	372:457	In this study, a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability was designed.					
36008982	5	12	theme	clay	673:676	arg1	laponite					688:695	laponite	688:695	laponite (LAP)	688:701	Furthermore, an aluminosilicate clay material, laponite (LAP), was incorporated into the hydrogel.					
36008982	5	12	theme	clay	673:676	arg1	material					678:685	an aluminosilicate clay material	654:685	an aluminosilicate clay material	654:685	Furthermore, an aluminosilicate clay material, laponite (LAP), was incorporated into the hydrogel.					
36008982	5	13	theme	aluminosilicate	657:671	arg1	laponite					688:695	laponite	688:695	laponite (LAP)	688:701	Furthermore, an aluminosilicate clay material, laponite (LAP), was incorporated into the hydrogel.					
36008982	5	13	theme	aluminosilicate	657:671	arg1	material					678:685	an aluminosilicate clay material	654:685	an aluminosilicate clay material	654:685	Furthermore, an aluminosilicate clay material, laponite (LAP), was incorporated into the hydrogel.					
36008982	2	14	theme	cross-linked	305:316	arg1	networks					318:325	biocompatible cross-linked networks	291:325	biocompatible cross-linked networks	291:325	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	8	15	theme	near-infrared	1185:1197	arg1	laser					1199:1203	a near-infrared laser	1183:1203	a near-infrared laser	1183:1203	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	7	16	theme	animal	1073:1078	arg1	levels					1080:1085	both the cell (cell viability was over 97%) and animal levels	1025:1085	levels	1080:1085	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	7	17	theme	composite	917:925	arg1	hydrogel					927:934	This composite hydrogel	912:934	This composite hydrogel	912:934	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	2	18	theme	biocompatible	291:303	arg1	networks					318:325	biocompatible cross-linked networks	291:325	biocompatible cross-linked networks	291:325	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	3	19	theme	photothermal	424:435	arg1	capability					448:457	photothermal conversion capability	424:457	photothermal conversion capability	424:457	In this study, a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability was designed.					
36008982	3	20	with	hydrogel	410:417	arg1	capability					448:457	photothermal conversion capability	424:457	photothermal conversion capability	424:457	In this study, a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability was designed.					
36008982	3	21	theme	conversion	437:446	arg1	capability					448:457	photothermal conversion capability	424:457	photothermal conversion capability	424:457	In this study, a chitosan/polyaniline/laponite (COL) hydrogel with photothermal conversion capability was designed.					
36008982	2	22	link	cross-linked	305:316	arg1	networks					318:325	biocompatible cross-linked networks	291:325	biocompatible cross-linked networks	291:325	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	0	23	theme	Chitosan/Polyaniline/Laponite	24:52	arg1	Hydrogel					54:61	Biocompatible Chitosan/Polyaniline/Laponite Hydrogel	10:61	Biocompatible Chitosan/Polyaniline/Laponite Hydrogel	10:61	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	1	24	theme	multifunctional	121:135	arg1	hydrogels					137:145	multifunctional hydrogels	121:145	multifunctional hydrogels	121:145	In recent years, multifunctional hydrogels have received a great deal of attention because they are biocompatible and can mimic the extracellular matrix.					
36008982	6	25	dep	%	820:820	arg1	%					894:894	45%	892:894	45%	892:894	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	0	26	theme	Biocompatible	10:22	arg1	Hydrogel					54:61	Biocompatible Chitosan/Polyaniline/Laponite Hydrogel	10:61	Biocompatible Chitosan/Polyaniline/Laponite Hydrogel	10:61	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	8	27	theme	conversion	1127:1136	arg1	efficiency					1138:1147	a photothermal conversion efficiency	1112:1147	a photothermal conversion efficiency of 23.7%	1112:1156	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	2	28	theme	photothermal	332:343	arg1	properties					345:354	photothermal properties	332:354	photothermal properties	332:354	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	9	29	contain	has	1294:1296	arg2	potential					1302:1310	the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration	1298:1393	the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration	1298:1393	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	9	29	contain	has	1294:1296	arg1	hydrogel					1285:1292	the COL hydrogel	1277:1292	the COL hydrogel	1277:1292	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	6	30	theme	mass-loss	867:875	arg1	ratio					877:881	the mass-loss ratio	863:881	the mass-loss ratio	863:881	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	6	31	theme	hydrogel	770:777	arg1	ratio					753:757	The swelling ratio	740:757	The swelling ratio of the COL hydrogel in various solutions	740:798	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	6	31	theme	hydrogel	770:777	arg1	%					820:820	greater than 580%	804:820	greater than 580%	804:820	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	0	32	theme	Hydrogel	54:61	arg1	Design					0:5	Design	0:5	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.	0:102	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	1	33	theme	extracellular	236:248	arg1	matrix					250:255	the extracellular matrix	232:255	the extracellular matrix	232:255	In recent years, multifunctional hydrogels have received a great deal of attention because they are biocompatible and can mimic the extracellular matrix.					
36008982	0	34	theme	Conversion	81:90	arg1	Capability					92:101	Photothermal Conversion Capability	68:101	Photothermal Conversion Capability	68:101	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	6	35	theme	various	782:788	arg1	solutions					790:798	various solutions	782:798	various solutions	782:798	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	0	36	theme	Photothermal	68:79	arg1	Capability					92:101	Photothermal Conversion Capability	68:101	Photothermal Conversion Capability	68:101	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	7	37	theme	cell	1040:1043	arg1	viability					1045:1053	cell viability	1040:1053	cell viability	1040:1053	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	9	38	theme	osteogenic	1223:1232	arg1	potential					1259:1267	the osteogenic differentiation-inducing potential	1219:1267	the osteogenic differentiation-inducing potential of LAP	1219:1274	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	9	39	theme	differentiation-inducing	1234:1257	arg1	potential					1259:1267	the osteogenic differentiation-inducing potential	1219:1267	the osteogenic differentiation-inducing potential of LAP	1219:1274	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	2	40	with	hydrogels	278:286	arg1	properties					345:354	photothermal properties	332:354	photothermal properties	332:354	Herein, we prepared hydrogels of biocompatible cross-linked networks with photothermal properties.					
36008982	8	41	theme	COL	1092:1094	arg1	hydrogel					1096:1103	The COL hydrogel	1088:1103	The COL hydrogel	1088:1103	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	6	42	theme	degradation	842:852	arg1	ability					854:860	good degradation ability	837:860	good degradation ability	837:860	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	0	43	with	Design	0:5	arg1	Capability					92:101	Photothermal Conversion Capability	68:101	Photothermal Conversion Capability	68:101	Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability.					
36008982	1	44	theme	recent	107:112	arg1	years					114:118	recent years	107:118	recent years	107:118	In recent years, multifunctional hydrogels have received a great deal of attention because they are biocompatible and can mimic the extracellular matrix.					
36008982	6	45	theme	good	837:840	arg1	ability					854:860	good degradation ability	837:860	good degradation ability	837:860	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	8	46	theme	%	1156:1156	arg1	efficiency					1138:1147	a photothermal conversion efficiency	1112:1147	a photothermal conversion efficiency of 23.7%	1112:1156	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	6	47	theme	COL	766:768	arg1	hydrogel					770:777	the COL hydrogel	762:777	the COL hydrogel	762:777	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	1	48	theme	great	163:167	arg1	deal					169:172	a great deal	161:172	a great deal of attention	161:185	In recent years, multifunctional hydrogels have received a great deal of attention because they are biocompatible and can mimic the extracellular matrix.					
36008982	8	49	theme	laser	1199:1203	arg1	irradiation					1168:1178	the irradiation	1164:1178	the irradiation of a near-infrared laser	1164:1203	The COL hydrogel showed a photothermal conversion efficiency of 23.7% under the irradiation of a near-infrared laser.					
36008982	9	50	theme	bone	1370:1373	arg1	regeneration					1382:1393	bone tissue regeneration	1370:1393	bone tissue regeneration	1370:1393	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	7	51	contain	have	956:959	arg2	biocompatibility					1005:1020	biocompatibility	1005:1020	biocompatibility	1005:1020	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	7	51	contain	have	956:959	arg1	hydrogel					927:934	This composite hydrogel	912:934	This composite hydrogel	912:934	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	7	51	contain	have	956:959	arg2	properties					990:999	good photothermal conversion properties	961:999	good photothermal conversion properties	961:999	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	9	52	theme	LAP	1272:1274	arg1	potential					1259:1267	the osteogenic differentiation-inducing potential	1219:1267	the osteogenic differentiation-inducing potential of LAP	1219:1274	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	9	53	theme	tissue	1375:1380	arg1	regeneration					1382:1393	bone tissue regeneration	1370:1393	bone tissue regeneration	1370:1393	Coupled with the osteogenic differentiation-inducing potential of LAP, the COL hydrogel has the potential to kill tumors via hyperthermia or serve as scaffolds for bone tissue regeneration.					
36008982	7	54	theme	good	961:964	arg1	properties					990:999	good photothermal conversion properties	961:999	good photothermal conversion properties	961:999	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36008982	6	55	from	ratio	753:757	arg1	solutions					790:798	various solutions	782:798	various solutions	782:798	The swelling ratio of the COL hydrogel in various solutions was greater than 580%, and it showed good degradation ability (the mass-loss ratio was over 45% after 28 days).					
36008982	7	56	dep	cell	1034:1037	arg1	%					1066:1066	97%	1064:1066	97%	1064:1066	This composite hydrogel was demonstrated to have good photothermal conversion properties and biocompatibility at both the cell (cell viability was over 97%) and animal levels.					
36184176	4	0	theme	various	722:728	arg1	groups					741:746	The various functional groups	718:746	The various functional groups on the surface-thiolated ACNCs	718:777	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	1	1	theme	biobased	279:286	arg1	reinforcements					296:309	sustainable biobased polymer reinforcements	267:309	sustainable biobased polymer reinforcements	267:309	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	0	2	theme	PVA-based	92:100	arg1	nanocomposites					102:115	PVA-based nanocomposites	92:115	PVA-based nanocomposites	92:115	Click chemistry-induced modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites.					
36184176	3	3	theme	one-pot	524:530	arg1	esterification					556:569	one-pot acid hydrolysis/Fischer esterification	524:569	one-pot acid hydrolysis/Fischer esterification	524:569	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	1	4	theme	polymer	288:294	arg1	reinforcements					296:309	sustainable biobased polymer reinforcements	267:309	sustainable biobased polymer reinforcements	267:309	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	4	5	theme	mechanical	985:994	arg1	properties					996:1005	mechanical properties	985:1005	mechanical properties	985:1005	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	5	6	theme	biobased	1196:1203	arg1	composites					1205:1214	biobased composites	1196:1214	biobased composites	1196:1214	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	4	7	theme	barrier	1016:1022	arg1	performance					1024:1034	gas barrier performance	1012:1034	gas barrier performance	1012:1034	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	8	theme	PVA	906:908	arg1	properties					996:1005	mechanical properties	985:1005	mechanical properties	985:1005	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	8	theme	PVA	906:908	arg1	properties					973:982	the thermal properties	961:982	the thermal properties	961:982	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	8	theme	PVA	906:908	arg1	performance					1024:1034	gas barrier performance	1012:1034	gas barrier performance	1012:1034	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	8	theme	PVA	906:908	arg1	nanocomposites					910:923	the PVA nanocomposites	902:923	the PVA nanocomposites	902:923	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	5	9	theme	excellent	1157:1165	arg1	nanofillers					1167:1177	excellent nanofillers	1157:1177	excellent nanofillers for PVA	1157:1185	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	5	9	theme	excellent	1157:1165	arg1	ACNCs					1084:1088	surface-thiolated ACNCs	1066:1088	surface-thiolated ACNCs with appropriate surface chemistry and loading levels	1066:1142	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	4	10	theme	PVA	875:877	arg1	matrix					879:884	the PVA matrix	871:884	the PVA matrix	871:884	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	11	theme	dispersion	799:808	arg1	stability					810:818	the dispersion stability	795:818	the dispersion stability	795:818	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	2	12	theme	tensile	394:400	arg1	strength					402:409	improved tensile strength	385:409	improved tensile strength	385:409	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	3	13	theme	hydrolysis/Fischer	537:554	arg1	esterification					556:569	one-pot acid hydrolysis/Fischer esterification	524:569	one-pot acid hydrolysis/Fischer esterification	524:569	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	2	14	theme	improved	385:392	arg1	strength					402:409	improved tensile strength	385:409	improved tensile strength	385:409	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	2	15	theme	poly	338:341	arg1	composites					369:378	poly (vinyl alcohol) (PVA)-CNC composites	338:378	poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers	338:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	1	16	theme	diverse	211:217	arg1	applications					219:230	their diverse applications	205:230	their diverse applications	205:230	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	4	17	theme	surface-thiolated	755:771	arg1	ACNCs					773:777	the surface-thiolated ACNCs	751:777	the surface-thiolated ACNCs	751:777	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	1	18	theme	surface	122:128	arg1	crucial					183:189	crucial	183:189	crucial	183:189	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	1	18	theme	surface	122:128	arg1	functionalization					130:146	The surface functionalization	118:146	The surface functionalization of cellulose nanocrystals (CNC)	118:178	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	2	19	theme	CNC-based	445:453	arg1	nanofillers					455:465	CNC-based nanofillers	445:465	CNC-based nanofillers	445:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	5	20	theme	loading	1129:1135	arg1	levels					1137:1142	appropriate surface chemistry and loading levels	1095:1142	levels	1137:1142	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	0	21	theme	cellulose	50:58	arg1	nanocrystals					60:71	acrylated cellulose nanocrystals	40:71	acrylated cellulose nanocrystals for application in PVA-based nanocomposites	40:115	Click chemistry-induced modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites.					
36184176	4	22	theme	functional	730:739	arg1	groups					741:746	The various functional groups	718:746	The various functional groups on the surface-thiolated ACNCs	718:777	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	3	23	theme	thiol-ene	631:639	arg1	reaction					641:648	a thiol-ene reaction	629:648	a thiol-ene reaction	629:648	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	2	24	theme	gas-barrier	415:425	arg1	performance					427:437	gas-barrier performance	415:437	gas-barrier performance using CNC-based nanofillers	415:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	0	25	theme	acrylated	40:48	arg1	nanocrystals					60:71	acrylated cellulose nanocrystals	40:71	acrylated cellulose nanocrystals for application in PVA-based nanocomposites	40:115	Click chemistry-induced modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites.					
36184176	4	26	theme	thermal	965:971	arg1	properties					973:982	the thermal properties	961:982	the thermal properties	961:982	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	27	theme	interfacial	841:851	arg1	interactions					853:864	their interfacial interactions	835:864	their interfacial interactions with the PVA matrix	835:884	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	5	28	with	ACNCs	1084:1088	arg1	chemistry					1115:1123	appropriate surface chemistry and loading levels	1095:1142	chemistry	1115:1123	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	5	28	with	ACNCs	1084:1088	arg1	levels					1137:1142	appropriate surface chemistry and loading levels	1095:1142	levels	1137:1142	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	4	29	theme	tailored	930:937	arg1	properties					939:948	tailored properties	930:948	tailored properties	930:948	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	0	30	from	application	77:87	arg1	nanocomposites					102:115	PVA-based nanocomposites	92:115	PVA-based nanocomposites	92:115	Click chemistry-induced modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites.					
36184176	0	31	theme	nanocrystals	60:71	arg1	modification					24:35	modification	24:35	modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites	24:115	Click chemistry-induced modification of acrylated cellulose nanocrystals for application in PVA-based nanocomposites.					
36184176	5	32	theme	desired	1221:1227	arg1	properties					1229:1238	desired properties	1221:1238	desired properties	1221:1238	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	5	33	theme	appropriate	1095:1105	arg1	chemistry					1115:1123	appropriate surface chemistry and loading levels	1095:1142	chemistry	1115:1123	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	1	34	theme	cellulose	151:159	arg1	nanocrystals					161:172	cellulose nanocrystals	151:172	cellulose nanocrystals (CNC)	151:178	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	1	34	theme	cellulose	151:159	arg1	CNC					175:177	CNC	175:177	CNC	175:177	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	4	35	with	nanocomposites	910:923	arg1	properties					939:948	tailored properties	930:948	tailored properties	930:948	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	5	36	theme	surface	1107:1113	arg1	chemistry					1115:1123	appropriate surface chemistry and loading levels	1095:1142	chemistry	1115:1123	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	3	37	theme	surface-thiolated	660:676	arg1	MACNC					700:704	MACNC	700:704	MACNC	700:704	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	3	37	theme	surface-thiolated	660:676	arg1	PACNC					711:715	PACNC	711:715	PACNC	711:715	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	3	37	theme	surface-thiolated	660:676	arg1	DACNC					693:697	DACNC	693:697	DACNC	693:697	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	3	37	theme	surface-thiolated	660:676	arg1	ACNCs					678:682	surface-thiolated ACNCs	660:682	surface-thiolated ACNCs	660:682	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	5	38	theme	surface-thiolated	1066:1082	arg1	nanofillers					1167:1177	excellent nanofillers	1157:1177	excellent nanofillers for PVA	1157:1185	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	5	38	theme	surface-thiolated	1066:1082	arg1	ACNCs					1084:1088	surface-thiolated ACNCs	1066:1088	surface-thiolated ACNCs with appropriate surface chemistry and loading levels	1066:1142	This study demonstrates that surface-thiolated ACNCs with appropriate surface chemistry and loading levels can serve as excellent nanofillers for PVA, forming biobased composites with desired properties.					
36184176	1	39	theme	nanocrystals	161:172	arg1	crucial					183:189	crucial	183:189	crucial	183:189	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	1	39	theme	nanocrystals	161:172	arg1	functionalization					130:146	The surface functionalization	118:146	The surface functionalization of cellulose nanocrystals (CNC)	118:178	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36184176	3	40	theme	surface	586:592	arg1	modification					594:605	surface modification	586:605	surface modification	586:605	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	2	41	with	composites	369:378	arg1	strength					402:409	improved tensile strength	385:409	improved tensile strength	385:409	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	2	41	with	composites	369:378	arg1	performance					427:437	gas-barrier performance	415:437	gas-barrier performance using CNC-based nanofillers	415:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	2	42	theme	vinyl	344:348	arg1	poly					338:341	poly	338:341	poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers	338:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	2	42	theme	vinyl	344:348	arg1	alcohol					350:356	vinyl alcohol	344:356	vinyl alcohol	344:356	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	4	43	from	groups	741:746	arg1	ACNCs					773:777	the surface-thiolated ACNCs	751:777	the surface-thiolated ACNCs	751:777	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	4	44	theme	gas	1012:1014	arg1	performance					1024:1034	gas barrier performance	1012:1034	gas barrier performance	1012:1034	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	3	45	theme	acid	532:535	arg1	esterification					556:569	one-pot acid hydrolysis/Fischer esterification	524:569	one-pot acid hydrolysis/Fischer esterification	524:569	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	3	46	theme	Acrylated	468:476	arg1	ACNCs					484:488	ACNCs	484:488	ACNCs	484:488	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	3	46	theme	Acrylated	468:476	arg1	CNCs					478:481	Acrylated CNCs	468:481	Acrylated CNCs (ACNCs)	468:489	Acrylated CNCs (ACNCs) were prepared from cellulose via one-pot acid hydrolysis/Fischer esterification; subsequently, surface modification was performed through a thiol-ene reaction to obtain surface-thiolated ACNCs, namely, DACNC, MACNC, and PACNC.					
36184176	4	47	with	interactions	853:864	arg1	matrix					879:884	the PVA matrix	871:884	the PVA matrix	871:884	The various functional groups on the surface-thiolated ACNCs not only affect the dispersion stability but also alter their interfacial interactions with the PVA matrix, thus realizing the PVA nanocomposites with tailored properties, including the thermal properties, mechanical properties, and gas barrier performance.					
36184176	2	48	theme	-CNC	364:367	arg1	composites					369:378	poly (vinyl alcohol) (PVA)-CNC composites	338:378	poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers	338:465	In this study, we develop poly (vinyl alcohol) (PVA)-CNC composites with improved tensile strength and gas-barrier performance using CNC-based nanofillers.					
36184176	1	49	theme	sustainable	267:277	arg1	reinforcements					296:309	sustainable biobased polymer reinforcements	267:309	sustainable biobased polymer reinforcements	267:309	The surface functionalization of cellulose nanocrystals (CNC) is crucial for promoting their diverse applications, especially regarding their use as sustainable biobased polymer reinforcements.					
36753895	7	0	from	decrease	1074:1081	arg1	yield					1086:1090	yield	1086:1090	yield	1086:1090	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	3	1	theme	composite	525:533	arg1	structural					502:511	structural	502:511	structural	502:511	After confirm the structural of prepared composite by various analysis, the adsorption properties were investigated.					
36753895	0	2	from	characterization	86:101	arg1	fast					127:130	fast	127:130	fast	127:130	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	4	3	theme	optimum	605:611	arg1	conditions					613:622	The optimum conditions	601:622	The optimum conditions	601:622	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	3	4	theme	adsorption	560:569	arg1	properties					571:580	the adsorption properties	556:580	the adsorption properties	556:580	After confirm the structural of prepared composite by various analysis, the adsorption properties were investigated.					
36753895	0	5	from	solution	166:173	arg1	characterization					86:101	characterization	86:101	characterization	86:101	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	5	from	solution	166:173	arg1	Preparation					73:83	Preparation	73:83	Preparation	73:83	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	5	from	solution	166:173	arg1	application					112:122	its application	108:122	its application in fast removing of BB41 dye from aqueous solution	108:173	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	6	from	Preparation	73:83	arg1	fast					127:130	fast	127:130	fast	127:130	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	5	7	theme	Longmuir	812:819	arg1	model					821:825	the Longmuir model	808:825	the Longmuir model	808:825	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	5	8	theme	single-layer	832:843	arg1	mechanism					845:853	single-layer mechanism	832:853	single-layer mechanism	832:853	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	2	9	theme	effective	409:417	arg1	nanocomposite					419:431	an effective nanocomposite	406:431	an effective nanocomposite for removing Basic blue 41 dye from aqueous media	406:481	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	0	10	theme	covalent	28:35	arg1	bionanocomposite					55:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite	0:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.	0:174	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	7	11	theme	24	1070:1071	arg1	%					1072:1072	%	1072:1072	%	1072:1072	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	6	12	theme	adsorption	871:880	arg1	kinetic					860:866	kinetic	860:866	kinetic	860:866	The kinetic of adsorption was studied and fitted with pseudo-second order model with R2 = 0.971.					
36753895	0	13	theme	κ-Carrageenan/triazin-based	0:26	arg1	bionanocomposite					55:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite	0:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.	0:174	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	7	14	theme	%	1072:1072	arg1	decrease					1074:1081	24% decrease	1070:1081	24% decrease in yield	1070:1090	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	4	15	theme	contact	672:678	arg1	time					680:683	contact time	672:683	contact time	672:683	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	0	16	theme	framework	45:53	arg1	bionanocomposite					55:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite	0:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.	0:174	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	2	17	theme	blue	452:455	arg1	dye					460:462	41 dye	457:462	Basic blue 41 dye	446:462	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	0	18	theme	organic	37:43	arg1	bionanocomposite					55:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite	0:70	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.	0:174	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	1	19	theme	triazine-based	295:308	arg1	framework					327:335	a triazine-based covalent organic framework	293:335	a triazine-based covalent organic framework as a co-adsorbent component	293:363	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36753895	2	20	theme	Basic	446:450	arg1	dye					460:462	41 dye	457:462	Basic blue 41 dye	446:462	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	5	21	theme	basic	764:768	arg1	adsorption					782:791	the basic blue 41 dye adsorption	760:791	the basic blue 41 dye adsorption	760:791	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	1	22	theme	covalent	310:317	arg1	framework					327:335	a triazine-based covalent organic framework	293:335	a triazine-based covalent organic framework as a co-adsorbent component	293:363	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36753895	5	23	theme	blue	770:773	arg1	adsorption					782:791	the basic blue 41 dye adsorption	760:791	the basic blue 41 dye adsorption	760:791	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	1	24	theme	organic	319:325	arg1	framework					327:335	a triazine-based covalent organic framework	293:335	a triazine-based covalent organic framework as a co-adsorbent component	293:363	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36753895	0	25	theme	dye	149:151	arg1	fast					127:130	fast	127:130	fast	127:130	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	4	26	theme	adsorbent	699:707	arg1	dosage					709:714	adsorbent dosage	699:714	adsorbent dosage of 10 mg	699:723	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	7	27	theme	833 mg/g	1005:1012	arg1	capacity					993:1000	the maximum adsorption capacity	970:1000	the maximum adsorption capacity of 833 mg/g	970:1012	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	2	28	attach	removing	437:444	arg2	nanocomposite					419:431	an effective nanocomposite	406:431	an effective nanocomposite for removing Basic blue 41 dye from aqueous media	406:481	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	2	28	attach	removing	437:444	arg1	media					477:481	aqueous media	469:481	aqueous media	469:481	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	7	29	theme	reusability	1045:1055	arg1	tests					1057:1061	the reusability tests	1041:1061	the reusability tests	1041:1061	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	5	30	theme	dye	778:780	arg1	adsorption					782:791	the basic blue 41 dye adsorption	760:791	the basic blue 41 dye adsorption	760:791	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	6	31	theme	order	924:928	arg1	model					930:934	pseudo-second order model	910:934	pseudo-second order model	910:934	The kinetic of adsorption was studied and fitted with pseudo-second order model with R2 = 0.971.					
36753895	0	32	theme	aqueous	158:164	arg1	solution					166:173	aqueous solution	158:173	aqueous solution	158:173	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	33	dep	bionanocomposite	55:70	arg1	characterization					86:101	characterization	86:101	characterization	86:101	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	33	dep	bionanocomposite	55:70	arg1	Preparation					73:83	Preparation	73:83	Preparation	73:83	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	0	33	dep	bionanocomposite	55:70	arg1	application					112:122	its application	108:122	its application in fast removing of BB41 dye from aqueous solution	108:173	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	3	34	theme	prepared	516:523	arg1	composite					525:533	prepared composite	516:533	prepared composite	516:533	After confirm the structural of prepared composite by various analysis, the adsorption properties were investigated.					
36753895	6	35	theme	pseudo-second	910:922	arg1	model					930:934	pseudo-second order model	910:934	pseudo-second order model	910:934	The kinetic of adsorption was studied and fitted with pseudo-second order model with R2 = 0.971.					
36753895	4	36	theme	10 mg	719:723	arg1	dosage					709:714	adsorbent dosage	699:714	adsorbent dosage of 10 mg	699:723	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	4	36	theme	10 mg	719:723	arg1	temperature					649:659	temperature	649:659	temperature	649:659	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	4	36	theme	10 mg	719:723	arg1	210 min					686:692	210 min	686:692	210 min	686:692	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	4	36	theme	10 mg	719:723	arg1	pH					642:643	pH	642:643	pH	642:643	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	4	36	theme	10 mg	719:723	arg1	25 °C					662:666	25 °C	662:666	25 °C	662:666	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	4	36	theme	10 mg	719:723	arg1	time					680:683	contact time	672:683	contact time	672:683	The optimum conditions were obtained in: pH: 7, temperature: 25 °C and contact time: 210 min; and adsorbent dosage of 10 mg.					
36753895	7	37	theme	maximum	974:980	arg1	capacity					993:1000	the maximum adsorption capacity	970:1000	the maximum adsorption capacity of 833 mg/g	970:1012	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	5	38	theme	isotherms	743:751	arg1	study					753:757	the isotherms study	739:757	the isotherms study	739:757	According to the isotherms study, the basic blue 41 dye adsorption was matched to the Longmuir model with single-layer mechanism.					
36753895	0	39	from	application	112:122	arg1	fast					127:130	fast	127:130	fast	127:130	κ-Carrageenan/triazin-based covalent organic framework bionanocomposite: Preparation, characterization, and its application in fast removing of BB41 dye from aqueous solution.					
36753895	7	40	theme	adsorption	982:991	arg1	capacity					993:1000	the maximum adsorption capacity	970:1000	the maximum adsorption capacity of 833 mg/g	970:1012	From the results the maximum adsorption capacity of 833 mg/g was obtained in 15 min and the reusability tests showed 24% decrease in yield after three cycles.					
36753895	3	41	theme	various	538:544	arg1	analysis					546:553	various analysis	538:553	various analysis	538:553	After confirm the structural of prepared composite by various analysis, the adsorption properties were investigated.					
36753895	1	42	theme	environmentally	238:252	arg1	substrate					263:271	an environmentally friendly substrate	235:271	an environmentally friendly substrate	235:271	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36753895	1	43	theme	co-adsorbent	342:353	arg1	component					355:363	a co-adsorbent component	340:363	a co-adsorbent component	340:363	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36753895	2	44	theme	aqueous	469:475	arg1	media					477:481	aqueous media	469:481	aqueous media	469:481	Combining these two precursors leads to an effective nanocomposite for removing Basic blue 41 dye from aqueous media.					
36753895	1	45	theme	friendly	254:261	arg1	substrate					263:271	an environmentally friendly substrate	235:271	an environmentally friendly substrate	235:271	A novel and high efficient adsorbent was prepared based on an environmentally friendly substrate, κ-carrageenan, and a triazine-based covalent organic framework as a co-adsorbent component.					
36555460	0	0	theme	Antimicrobial	96:108	arg1	Material					110:117	Innovative Antimicrobial Material	85:117	Innovative Antimicrobial Material	85:117	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	7	1	theme	material	1348:1355	arg1	prospects					1330:1338	the prospects	1326:1338	the prospects of this material for the development of smart and biodegradable food packaging applications	1326:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	3	2	theme	effective	536:544	arg1	alternative					546:556	a potential novel and effective alternative	514:556	a potential novel and effective alternative to conventional antimicrobial materials	514:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36555460	0	3	theme	Innovative	85:94	arg1	Material					110:117	Innovative Antimicrobial Material	85:117	Innovative Antimicrobial Material	85:117	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	6	4	theme	antimicrobial	940:952	arg1	due					986:988	due	986:988	due	986:988	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	4	theme	antimicrobial	940:952	arg1	activity					954:961	the antimicrobial activity	936:961	the antimicrobial activity	936:961	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	3	5	theme	alternative	546:556	arg1	development					499:509	the development	495:509	the development of a potential novel and effective alternative to conventional antimicrobial materials	495:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36555460	6	6	theme	inorganic	1010:1018	arg1	components					1020:1029	both organic and inorganic components	993:1029	both organic and inorganic components	993:1029	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	7	7	theme	biodegradable	1390:1402	arg1	applications					1419:1430	smart and biodegradable food packaging applications	1380:1430	smart and biodegradable food packaging applications	1380:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	2	8	theme	electron	332:339	arg1	microscopy					341:350	scanning electron microscopy	323:350	scanning electron microscopy	323:350	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	6	9	dep	pathogens	1097:1105	arg1	aureus					1123:1128	Staphylococcus aureus	1108:1128	Staphylococcus aureus	1108:1128	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	9	dep	pathogens	1097:1105	arg1	enterica					1145:1152	Salmonella enterica	1134:1152	Salmonella enterica	1134:1152	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	10	theme	inhibition	1179:1188	arg1	zone					1190:1193	a clear inhibition zone	1171:1193	a clear inhibition zone of 1.2 cm for the most complex nanocomposition	1171:1240	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	11	theme	clear	1173:1177	arg1	zone					1190:1193	a clear inhibition zone	1171:1193	a clear inhibition zone of 1.2 cm for the most complex nanocomposition	1171:1240	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	4	12	theme	solid	784:788	arg1	material					800:807	a solid composite material	782:807	a solid composite material	782:807	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	2	13	theme	scanning	323:330	arg1	microscopy					341:350	scanning electron microscopy	323:350	scanning electron microscopy	323:350	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	3	14	theme	potential	516:524	arg1	alternative					546:556	a potential novel and effective alternative	514:556	a potential novel and effective alternative to conventional antimicrobial materials	514:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36555460	7	15	theme	6-month-old	1299:1309	arg1	samples					1311:1317	fresh and 6-month-old samples	1289:1317	fresh and 6-month-old samples	1289:1317	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	3	16	theme	antimicrobial	574:586	arg1	materials					588:596	conventional antimicrobial materials	561:596	conventional antimicrobial materials	561:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36555460	6	17	theme	organic	998:1004	arg1	components					1020:1029	both organic and inorganic components	993:1029	both organic and inorganic components	993:1029	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	5	18	theme	improved	846:853	arg1	percentage					868:877	improved water uptake percentage	846:877	improved water uptake percentage	846:877	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	2	19	theme	applications	446:457	arg1	range					437:441	their potential range	421:441	their potential range of applications	421:457	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	0	20	theme	Bioinspired	14:24	arg1	Films					34:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	1	21	with	films	139:143	arg1	activity					186:193	potential antimicrobial synergistic activity	150:193	potential antimicrobial synergistic activity	150:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	2	22	theme	photoelectron	359:371	arg1	spectroscopy					373:384	X-ray photoelectron spectroscopy	353:384	X-ray photoelectron spectroscopy	353:384	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	6	23	theme	foodborne	1087:1095	arg1	pathogens					1097:1105	common foodborne pathogens	1080:1105	common foodborne pathogens (Staphylococcus aureus and Salmonella enterica)	1080:1153	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	0	24	theme	Self-Standing	0:12	arg1	Films					34:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	2	25	theme	X-ray	353:357	arg1	spectroscopy					373:384	X-ray photoelectron spectroscopy	353:384	X-ray photoelectron spectroscopy	353:384	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	4	26	theme	composite	790:798	arg1	material					800:807	a solid composite material	782:807	a solid composite material	782:807	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	1	27	theme	simple	219:224	arg1	synthesis					241:249	a simple green chemical synthesis	217:249	a simple green chemical synthesis with overnight thermal treatment	217:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	5	28	theme	water	855:859	arg1	percentage					868:877	improved water uptake percentage	846:877	improved water uptake percentage	846:877	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	1	29	with	synthesis	241:249	arg1	treatment					274:282	overnight thermal treatment	256:282	overnight thermal treatment	256:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	1	30	theme	Thin	120:123	arg1	films					139:143	Thin self-standing films	120:143	Thin self-standing films with potential antimicrobial synergistic activity	120:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	1	31	theme	green	226:230	arg1	synthesis					241:249	a simple green chemical synthesis	217:249	a simple green chemical synthesis with overnight thermal treatment	217:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	0	32	theme	Polymer	26:32	arg1	Films					34:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films	0:38	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	4	33	theme	polymer	628:634	arg1	blend					636:640	an antimicrobial polymer blend	611:640	an antimicrobial polymer blend	611:640	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	2	34	theme	potential	427:435	arg1	range					437:441	their potential range	421:441	their potential range of applications	421:457	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	6	35	theme	cm	1202:1203	arg1	zone					1190:1193	a clear inhibition zone	1171:1193	a clear inhibition zone of 1.2 cm for the most complex nanocomposition	1171:1240	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	1	36	theme	self-standing	125:137	arg1	films					139:143	Thin self-standing films	120:143	Thin self-standing films with potential antimicrobial synergistic activity	120:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	1	37	theme	chemical	232:239	arg1	synthesis					241:249	a simple green chemical synthesis	217:249	a simple green chemical synthesis with overnight thermal treatment	217:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	4	38	theme	antimicrobial	614:626	arg1	blend					636:640	an antimicrobial polymer blend	611:640	an antimicrobial polymer blend	611:640	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	6	39	theme	Kirby-Bauer	1054:1064	arg1	assay					1066:1070	Kirby-Bauer assay	1054:1070	Kirby-Bauer assay	1054:1070	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	7	40	theme	packaging	1409:1417	arg1	applications					1419:1430	smart and biodegradable food packaging applications	1380:1430	smart and biodegradable food packaging applications	1380:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	4	41	theme	silver	696:701	arg1	nanophases					703:712	fine (~25 nm) silver nanophases	682:712	fine (~25 nm) silver nanophases	682:712	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	5	42	theme	better	883:888	arg1	stability					890:898	better stability	883:898	better stability	883:898	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	5	43	theme	resulting	814:822	arg1	matrix					832:837	The resulting polymer matrix	810:837	The resulting polymer matrix	810:837	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	7	44	theme	applications	1419:1430	arg1	development					1365:1375	the development	1361:1375	the development of smart and biodegradable food packaging applications	1361:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	0	45	theme	Silver	61:66	arg1	Nanoparticles					68:80	Ultrafine Silver Nanoparticles	51:80	Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material	51:117	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	5	46	theme	water	919:923	arg1	presence					907:914	the presence	903:914	the presence of water	903:923	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	7	47	theme	excellent	1247:1255	arg1	performance					1257:1267	The excellent performance	1243:1267	The excellent performance against bacteria of fresh and 6-month-old samples	1243:1317	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	4	48	dep	fine	682:685	arg1	nm					692:693	~25 nm	688:693	~25 nm	688:693	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	3	49	theme	novel	526:530	arg1	alternative					546:556	a potential novel and effective alternative	514:556	a potential novel and effective alternative to conventional antimicrobial materials	514:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36555460	0	50	theme	Ultrafine	51:59	arg1	Nanoparticles					68:80	Ultrafine Silver Nanoparticles	51:80	Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material	51:117	Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.					
36555460	6	51	theme	films	970:974	arg1	due					986:988	due	986:988	due	986:988	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	51	theme	films	970:974	arg1	activity					954:961	the antimicrobial activity	936:961	the antimicrobial activity	936:961	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	6	52	theme	common	1080:1085	arg1	pathogens					1097:1105	common foodborne pathogens	1080:1105	common foodborne pathogens (Staphylococcus aureus and Salmonella enterica)	1080:1153	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	7	53	theme	food	1404:1407	arg1	applications					1419:1430	smart and biodegradable food packaging applications	1380:1430	smart and biodegradable food packaging applications	1380:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	2	54	theme	other	390:394	arg1	techniques					396:405	other techniques	390:405	other techniques	390:405	Their properties have been studied by scanning electron microscopy, X-ray photoelectron spectroscopy and other techniques to understand their potential range of applications.					
36555460	7	55	theme	smart	1380:1384	arg1	applications					1419:1430	smart and biodegradable food packaging applications	1380:1430	smart and biodegradable food packaging applications	1380:1430	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	6	56	theme	complex	1218:1224	arg1	nanocomposition					1226:1240	the most complex nanocomposition	1209:1240	the most complex nanocomposition	1209:1240	Moreover, the antimicrobial activity of the films, which is due to both organic and inorganic components, has been evaluated by Kirby-Bauer assay against common foodborne pathogens (Staphylococcus aureus and Salmonella enterica) and resulted in a clear inhibition zone of 1.2 cm for the most complex nanocomposition.					
36555460	1	57	theme	potential	150:158	arg1	activity					186:193	potential antimicrobial synergistic activity	150:193	potential antimicrobial synergistic activity	150:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	1	58	theme	overnight	256:264	arg1	treatment					274:282	overnight thermal treatment	256:282	overnight thermal treatment	256:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	7	59	theme	samples	1311:1317	arg1	bacteria					1277:1284	bacteria	1277:1284	bacteria of fresh and 6-month-old samples	1277:1317	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	4	60	theme	film-forming	747:758	arg1	properties					760:769	its film-forming properties	743:769	its film-forming properties	743:769	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	1	61	theme	antimicrobial	160:172	arg1	activity					186:193	potential antimicrobial synergistic activity	150:193	potential antimicrobial synergistic activity	150:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	1	62	theme	thermal	266:272	arg1	treatment					274:282	overnight thermal treatment	256:282	overnight thermal treatment	256:282	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	4	63	theme	fine	682:685	arg1	nanophases					703:712	fine (~25 nm) silver nanophases	682:712	fine (~25 nm) silver nanophases	682:712	By creating an antimicrobial polymer blend, and using it to develop and immobilize fine (~25 nm) silver nanophases, we further aimed to exploit its film-forming properties and create a solid composite material.					
36555460	1	64	theme	synergistic	174:184	arg1	activity					186:193	potential antimicrobial synergistic activity	150:193	potential antimicrobial synergistic activity	150:193	Thin self-standing films with potential antimicrobial synergistic activity have been produced by a simple green chemical synthesis with overnight thermal treatment.					
36555460	5	65	theme	polymer	824:830	arg1	matrix					832:837	The resulting polymer matrix	810:837	The resulting polymer matrix	810:837	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	5	66	theme	uptake	861:866	arg1	percentage					868:877	improved water uptake percentage	846:877	improved water uptake percentage	846:877	The resulting polymer matrix showed improved water uptake percentage and better stability in the presence of water.					
36555460	7	67	theme	fresh	1289:1293	arg1	samples					1311:1317	fresh and 6-month-old samples	1289:1317	fresh and 6-month-old samples	1289:1317	The excellent performance against bacteria of fresh and 6-month-old samples proves the prospects of this material for the development of smart and biodegradable food packaging applications.					
36555460	3	68	theme	conventional	561:572	arg1	materials					588:596	conventional antimicrobial materials	561:596	conventional antimicrobial materials	561:596	In this work, the focus was set on the development of a potential novel and effective alternative to conventional antimicrobial materials.					
36965561	5	0	theme	formed	1086:1091	arg1	SNPs					1093:1096	formed SNPs	1086:1096	formed SNPs	1086:1096	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	1	1	theme	colloidal	164:172	arg1	forms					174:178	colloidal forms	164:178	colloidal forms	164:178	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	5	2	theme	197 nm	1212:1217	arg1	size					1138:1141	particle size	1129:1141	particle size	1129:1141	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	162 °C					1244:1249	162 °C	1244:1249	162 °C	1244:1249	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	-13.9 mV					1220:1227	-13.9 mV	1220:1227	-13.9 mV	1220:1227	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	area					1177:1180	specific surface area	1160:1180	specific surface area	1160:1180	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	temperature					1197:1207	decomposition temperature	1183:1207	decomposition temperature of 197 nm	1183:1217	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	potential					1149:1157	zeta potential	1144:1157	zeta potential	1144:1157	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	2	theme	197 nm	1212:1217	arg1	m2g-1					1234:1238	1.9 m2g-1	1230:1238	1.9 m2g-1	1230:1238	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	1	3	theme	autoclave	278:286	arg1	heating					327:333	autoclave, microwave, ultrasonication and normal heating	278:333	autoclave, microwave, ultrasonication and normal heating with stirring	278:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	2	4	from	SNPs	363:366	arg1	form					378:381	powder form	371:381	powder form	371:381	Furthermore, SNPs in powder form were prepared using freeze drying technique.					
36965561	5	5	theme	powder	1098:1103	arg1	SNPs					1093:1096	formed SNPs	1086:1096	formed SNPs	1086:1096	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	4	6	theme	zeta	849:852	arg1	-10.8 mV					865:872	-10.8 mV	865:872	-10.8 mV	865:872	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	6	theme	zeta	849:852	arg1	potential					854:862	highest zeta potential	841:862	highest zeta potential (-10.8 mV)	841:873	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	5	7	theme	optimal	930:936	arg1	conditions					938:947	optimal conditions	930:947	optimal conditions	930:947	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	1	8	theme	microwave	289:297	arg1	heating					327:333	autoclave, microwave, ultrasonication and normal heating	278:333	autoclave, microwave, ultrasonication and normal heating with stirring	278:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	7	9	theme	emulsification	1389:1402	arg1	ability					1404:1410	emulsification ability	1389:1410	emulsification ability of SNPs powder	1389:1425	Results revealed that emulsification ability of SNPs powder was three times higher than that of the native starch.					
36965561	4	10	theme	highest	841:847	arg1	-10.8 mV					865:872	-10.8 mV	865:872	-10.8 mV	865:872	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	10	theme	highest	841:847	arg1	potential					854:862	highest zeta potential	841:862	highest zeta potential (-10.8 mV)	841:873	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	11	theme	composite	706:714	arg1	design					716:721	central composite design	698:721	central composite design	698:721	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	5	12	theme	particle	1129:1136	arg1	size					1138:1141	particle size	1129:1141	particle size	1129:1141	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	2	13	theme	powder	371:376	arg1	form					378:381	powder form	371:381	powder form	371:381	Furthermore, SNPs in powder form were prepared using freeze drying technique.					
36965561	5	14	with	powder	1098:1103	arg1	squared-shape					1110:1122	squared-shape	1110:1122	squared-shape	1110:1122	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	3	15	theme	particle	545:552	arg1	151 nm					560:565	151 nm	560:565	151 nm	560:565	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	15	theme	particle	545:552	arg1	size					554:557	mean particle size	540:557	mean particle size (151 nm)	540:566	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	16	theme	formed	455:460	arg1	SNPs					462:465	the formed SNPs	451:465	the formed SNPs using starch solution (1 % W/V) and ultrasonication technique	451:527	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	5	17	theme	surface	1169:1175	arg1	area					1177:1180	specific surface area	1160:1180	specific surface area	1160:1180	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	4	18	theme	particle	813:820	arg1	49.3 nm					828:834	49.3 nm	828:834	49.3 nm	828:834	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	18	theme	particle	813:820	arg1	size					822:825	lowest particle size	806:825	lowest particle size (49.3 nm)	806:835	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	19	theme	α-amylase	755:763	arg1	time					780:783	sonication time	769:783	sonication time of 15 min	769:793	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	19	theme	α-amylase	755:763	arg1	1.5 mL					745:750	1.5 mL	745:750	1.5 mL of α-amylase	745:763	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	3	20	theme	starch	473:478	arg1	 W/V					493:496	1 % W/V	490:496	1 % W/V	490:496	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	20	theme	starch	473:478	arg1	solution					480:487	starch solution	473:487	starch solution (1 % W/V)	473:497	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	5	21	theme	zeta	1144:1147	arg1	potential					1149:1157	zeta potential	1144:1157	zeta potential	1144:1157	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	1	22	with	heating	327:333	arg1	stirring					340:347	stirring	340:347	stirring	340:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	5	23	theme	prepared	896:903	arg1	solution					915:922	prepared colloidal solution	896:922	prepared colloidal solution	896:922	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	24	theme	24 h.	1057:1061	arg1	Results					1063:1069	24 h. Results	1057:1069	24 h. Results	1057:1069	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	2	25	theme	drying	410:415	arg1	technique					417:425	freeze drying technique	403:425	freeze drying technique	403:425	Furthermore, SNPs in powder form were prepared using freeze drying technique.					
36965561	1	26	theme	ultrasonication	300:314	arg1	heating					327:333	autoclave, microwave, ultrasonication and normal heating	278:333	autoclave, microwave, ultrasonication and normal heating with stirring	278:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	5	27	theme	colloidal	905:913	arg1	solution					915:922	prepared colloidal solution	896:922	prepared colloidal solution	896:922	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	2	28	theme	freeze	403:408	arg1	technique					417:425	freeze drying technique	403:425	freeze drying technique	403:425	Furthermore, SNPs in powder form were prepared using freeze drying technique.					
36965561	0	29	theme	starch	29:34	arg1	preparation					14:24	preparation	14:24	preparation of starch	14:34	Enzymatically preparation of starch nanoparticles using freeze drying technique - Gelatinization, optimization and characterization.					
36965561	6	30	theme	native	1277:1282	arg1	starch					1284:1289	native starch	1277:1289	native starch	1277:1289	While, for native starch these values were 5018 nm, -6.01 mV, 0.68 m2g-1 and 170.2 °C, respectively.					
36965561	1	31	from	nanoparticles	140:152	arg1	forms					174:178	colloidal forms	164:178	colloidal forms	164:178	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	3	32	dep	lowest	533:538	arg1	values					622:627	zeta potential (-8.8 mV) values	597:627	zeta potential (-8.8 mV) values	597:627	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	32	dep	lowest	533:538	arg1	151 nm					560:565	151 nm	560:565	151 nm	560:565	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	32	dep	lowest	533:538	arg1	PDI					572:574	PDI (0.173)	572:582	PDI (0.173)	572:582	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	32	dep	lowest	533:538	arg1	size					554:557	mean particle size	540:557	mean particle size (151 nm)	540:566	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	33	theme	1 	490:491	arg1	%					492:492	%	492:492	%	492:492	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	1	34	theme	normal	320:325	arg1	heating					327:333	autoclave, microwave, ultrasonication and normal heating	278:333	autoclave, microwave, ultrasonication and normal heating with stirring	278:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	3	35	theme	%	492:492	arg1	 W/V					493:496	1 % W/V	490:496	1 % W/V	490:496	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	35	theme	%	492:492	arg1	solution					480:487	starch solution	473:487	starch solution (1 % W/V)	473:497	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	4	36	theme	response	659:666	arg1	methodology					676:686	response surface methodology	659:686	response surface methodology	659:686	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	5	37	theme	100 Pa	1033:1038	arg1	temperature					1018:1028	temperature	1018:1028	temperature	1018:1028	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	37	theme	100 Pa	1033:1038	arg1	pressure					1005:1012	pressure	1005:1012	pressure	1005:1012	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	38	theme	freeze	979:984	arg1	dryer					986:990	freeze dryer	979:990	freeze dryer	979:990	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	39	dep	dryer	986:990	arg1	indicated					1071:1079	indicated	1071:1079	indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively	1071:1263	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	3	40	theme	-8.8 mV	613:619	arg1	values					622:627	zeta potential (-8.8 mV) values	597:627	zeta potential (-8.8 mV) values	597:627	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	5	41	theme	decomposition	1183:1195	arg1	temperature					1197:1207	decomposition temperature	1183:1207	decomposition temperature of 197 nm	1183:1217	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	1	42	theme	different	236:244	arg1	methods					261:267	four different gelatinization methods	231:267	four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring	231:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	0	43	theme	drying	63:68	arg1	technique					70:78	freeze drying technique	56:78	freeze drying technique	56:78	Enzymatically preparation of starch nanoparticles using freeze drying technique - Gelatinization, optimization and characterization.					
36965561	5	44	contain	had	1125:1127	arg2	temperature					1197:1207	decomposition temperature	1183:1207	decomposition temperature of 197 nm	1183:1217	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	162 °C					1244:1249	162 °C	1244:1249	162 °C	1244:1249	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg1	SNPs					1093:1096	formed SNPs	1086:1096	formed SNPs	1086:1096	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	m2g-1					1234:1238	1.9 m2g-1	1230:1238	1.9 m2g-1	1230:1238	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	potential					1149:1157	zeta potential	1144:1157	zeta potential	1144:1157	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	size					1138:1141	particle size	1129:1141	particle size	1129:1141	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	-13.9 mV					1220:1227	-13.9 mV	1220:1227	-13.9 mV	1220:1227	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	5	44	contain	had	1125:1127	arg2	area					1177:1180	specific surface area	1160:1180	specific surface area	1160:1180	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	4	45	theme	lowest	806:811	arg1	49.3 nm					828:834	49.3 nm	828:834	49.3 nm	828:834	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	45	theme	lowest	806:811	arg1	size					822:825	lowest particle size	806:825	lowest particle size (49.3 nm)	806:835	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	1	46	theme	Starch	133:138	arg1	SNPs					155:158	SNPs	155:158	SNPs	155:158	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	1	46	theme	Starch	133:138	arg1	nanoparticles					140:152	Starch nanoparticles	133:152	Starch nanoparticles (SNPs) in colloidal forms	133:178	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	0	47	theme	freeze	56:61	arg1	technique					70:78	freeze drying technique	56:78	freeze drying technique	56:78	Enzymatically preparation of starch nanoparticles using freeze drying technique - Gelatinization, optimization and characterization.					
36965561	7	48	theme	powder	1420:1425	arg1	ability					1404:1410	emulsification ability	1389:1410	emulsification ability of SNPs powder	1389:1425	Results revealed that emulsification ability of SNPs powder was three times higher than that of the native starch.					
36965561	7	49	theme	higher	1443:1448	arg1	times					1437:1441	three times	1431:1441	three times higher than that of the native starch	1431:1479	Results revealed that emulsification ability of SNPs powder was three times higher than that of the native starch.					
36965561	6	50	dep	5018 nm	1309:1315	arg1	While					1266:1270	While	1266:1270	While	1266:1270	While, for native starch these values were 5018 nm, -6.01 mV, 0.68 m2g-1 and 170.2 °C, respectively.					
36965561	3	51	theme	ultrasonication	503:517	arg1	technique					519:527	ultrasonication technique	503:527	ultrasonication technique	503:527	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	7	52	theme	native	1467:1472	arg1	starch					1474:1479	the native starch	1463:1479	the native starch	1463:1479	Results revealed that emulsification ability of SNPs powder was three times higher than that of the native starch.					
36965561	4	53	theme	central	698:704	arg1	design					716:721	central composite design	698:721	central composite design	698:721	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	3	54	theme	potential	602:610	arg1	values					622:627	zeta potential (-8.8 mV) values	597:627	zeta potential (-8.8 mV) values	597:627	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	7	55	theme	SNPs	1415:1418	arg1	powder					1420:1425	SNPs powder	1415:1425	SNPs powder	1415:1425	Results revealed that emulsification ability of SNPs powder was three times higher than that of the native starch.					
36965561	1	56	theme	gelatinization	246:259	arg1	methods					261:267	four different gelatinization methods	231:267	four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring	231:347	Starch nanoparticles (SNPs) in colloidal forms were prepared using enzymatically pretreatment and four different gelatinization methods based on autoclave, microwave, ultrasonication and normal heating with stirring.					
36965561	5	57	theme	SNPs	950:953	arg1	powder					955:960	SNPs powder	950:960	SNPs powder	950:960	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	4	58	theme	sonication	769:778	arg1	time					780:783	sonication time	769:783	sonication time of 15 min	769:793	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	59	theme	surface	668:674	arg1	methodology					676:686	response surface methodology	659:686	response surface methodology	659:686	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	60	theme	15 min	788:793	arg1	time					780:783	sonication time	769:783	sonication time of 15 min	769:793	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	60	theme	15 min	788:793	arg1	1.5 mL					745:750	1.5 mL	745:750	1.5 mL of α-amylase	745:763	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	61	theme	Optimization	630:641	arg1	procedure					643:651	Optimization procedure	630:651	Optimization procedure using response surface methodology, based on central composite design,	630:722	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	62	with	SNPs	796:799	arg1	-10.8 mV					865:872	-10.8 mV	865:872	-10.8 mV	865:872	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	62	with	SNPs	796:799	arg1	potential					854:862	highest zeta potential	841:862	highest zeta potential (-10.8 mV)	841:873	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	62	with	SNPs	796:799	arg1	49.3 nm					828:834	49.3 nm	828:834	49.3 nm	828:834	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	4	62	with	SNPs	796:799	arg1	size					822:825	lowest particle size	806:825	lowest particle size (49.3 nm)	806:835	Optimization procedure using response surface methodology, based on central composite design, indicated that using 1.5 mL of α-amylase and sonication time of 15 min, SNPs with lowest particle size (49.3 nm) and highest zeta potential (-10.8 mV) were produced.					
36965561	5	63	theme	specific	1160:1167	arg1	area					1177:1180	specific surface area	1160:1180	specific surface area	1160:1180	Using prepared colloidal solution under optimal conditions, SNPs powder were produced by freeze dryer, adjusted at pressure and temperature of 100 Pa and - 70 °C, for 24 h. Results indicated that formed SNPs powder with squared-shape, had particle size, zeta potential, specific surface area, decomposition temperature of 197 nm, -13.9 mV, 1.9 m2g-1 and 162 °C, respectively.					
36965561	3	64	contain	had	529:531	arg2	lowest					533:538	lowest	533:538	lowest	533:538	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	64	contain	had	529:531	arg1	SNPs					462:465	the formed SNPs	451:465	the formed SNPs using starch solution (1 % W/V) and ultrasonication technique	451:527	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	64	contain	had	529:531	arg2	highest					589:595	highest	589:595	highest	589:595	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	65	theme	zeta	597:600	arg1	values					622:627	zeta potential (-8.8 mV) values	597:627	zeta potential (-8.8 mV) values	597:627	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	66	theme	mean	540:543	arg1	151 nm					560:565	151 nm	560:565	151 nm	560:565	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
36965561	3	66	theme	mean	540:543	arg1	size					554:557	mean particle size	540:557	mean particle size (151 nm)	540:566	Results indicated that the formed SNPs using starch solution (1 % W/V) and ultrasonication technique had lowest mean particle size (151 nm) and PDI (0.173), and highest zeta potential (-8.8 mV) values.					
35396930	6	0	theme	proliferation	1169:1181	arg1	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	7	1	theme	sciatic	1204:1210	arg1	model					1225:1229	the rat sciatic nerve defect model	1196:1229	the rat sciatic nerve defect model	1196:1229	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	2	2	theme	nerve	299:303	arg1	conduit					305:311	the traditional hollow nerve conduit	276:311	the traditional hollow nerve conduit	276:311	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	2	theme	nerve	299:303	arg1	satisfactory					320:331	satisfactory	320:331	satisfactory	320:331	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	9	3	theme	double-layer	1550:1561	arg1	conduit					1582:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	9	4	theme	nerve	1625:1629	arg1	repairing					1631:1639	peripheral nerve repairing	1614:1639	peripheral nerve repairing	1614:1639	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	2	5	from	repair	353:358	arg1	conduit					305:311	the traditional hollow nerve conduit	276:311	the traditional hollow nerve conduit	276:311	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	5	from	repair	353:358	arg1	satisfactory					320:331	satisfactory	320:331	satisfactory	320:331	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	6	theme	traditional	280:290	arg1	conduit					305:311	the traditional hollow nerve conduit	276:311	the traditional hollow nerve conduit	276:311	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	6	theme	traditional	280:290	arg1	satisfactory					320:331	satisfactory	320:331	satisfactory	320:331	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	5	7	theme	Schiff	913:918	arg1	reaction					925:932	the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit	909:990	the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit	909:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	3	8	link	cross-linked	443:454	arg1	hydrogels					456:464	the double cross-linked hydrogels	432:464	the double cross-linked hydrogels with injectable, self-healing, and conductive properties	432:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	7	9	theme	composite	1249:1257	arg1	conduit					1274:1280	the double-layer composite hydrogel nerve conduit	1232:1280	the double-layer composite hydrogel nerve conduit	1232:1280	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	4	10	theme	conductive	717:726	arg1	hydrogel					728:735	The conductive hydrogel	713:735	The conductive hydrogel	713:735	The conductive hydrogel is injected into the cavity of chitosan conduit prepared by electrodeposition.					
35396930	3	11	theme	carboxymethyl	596:608	arg1	chitosan					610:617	carboxymethyl chitosan	596:617	carboxymethyl chitosan	596:617	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	6	12	theme	hydrogel	1020:1027	arg1	conduit					1036:1042	The double-layer composite hydrogel neural conduit	993:1042	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF)	993:1081	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	3	13	theme	double	436:441	arg1	hydrogels					456:464	the double cross-linked hydrogels	432:464	the double cross-linked hydrogels with injectable, self-healing, and conductive properties	432:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	2	14	theme	peripheral	247:256	arg1	repair					264:269	peripheral nerve repair	247:269	peripheral nerve repair	247:269	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	9	15	theme	peripheral	1614:1623	arg1	repairing					1631:1639	peripheral nerve repairing	1614:1639	peripheral nerve repairing	1614:1639	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	6	16	theme	double-layer	997:1008	arg1	conduit					1036:1042	The double-layer composite hydrogel neural conduit	993:1042	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF)	993:1081	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	8	17	theme	repair	1393:1398	arg1	ability					1400:1406	the repair ability	1389:1406	the repair ability of double-layered hydrogel nerve conduit loaded with DHF	1389:1463	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	8	17	theme	repair	1393:1398	arg1	comparable					1468:1477	comparable	1468:1477	comparable	1468:1477	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	3	18	theme	Pluronic	641:648	arg1	F-127					650:654	aldehyde-modified Pluronic F-127	623:654	aldehyde-modified Pluronic F-127 (F127-CHO)	623:665	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	18	theme	Pluronic	641:648	arg1	F127-CHO					657:664	F127-CHO	657:664	F127-CHO	657:664	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	5	19	theme	hydrogel	969:976	arg1	conduit					984:990	a double-layer composite hydrogel nerve conduit	944:990	a double-layer composite hydrogel nerve conduit	944:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	4	20	theme	chitosan	768:775	arg1	conduit					777:783	chitosan conduit	768:783	chitosan conduit prepared by electrodeposition	768:813	The conductive hydrogel is injected into the cavity of chitosan conduit prepared by electrodeposition.					
35396930	3	21	with	hydrogels	456:464	arg1	properties					512:521	injectable, self-healing, and conductive properties	471:521	injectable, self-healing, and conductive properties	471:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	6	22	theme	excellent	1087:1095	arg1	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	8	23	theme	hydrogel	1426:1433	arg1	conduit					1441:1447	double-layered hydrogel nerve conduit	1411:1447	double-layered hydrogel nerve conduit	1411:1447	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	7	24	theme	double-layer	1236:1247	arg1	conduit					1274:1280	the double-layer composite hydrogel nerve conduit	1232:1280	the double-layer composite hydrogel nerve conduit	1232:1280	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	1	25	theme	major	165:169	arg1	recovery					151:158	functional recovery	140:158	functional recovery	140:158	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	25	theme	major	165:169	arg1	challenge					171:179	a major challenge	163:179	a major challenge in clinical practice	163:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	25	theme	major	165:169	arg1	regeneration					123:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	9	26	contain	has	1590:1592	arg1	conduit					1582:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	9	26	contain	has	1590:1592	arg2	potential					1600:1608	great potential	1594:1608	great potential for peripheral nerve repairing	1594:1639	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	8	27	theme	conduit	1441:1447	arg1	ability					1400:1406	the repair ability	1389:1406	the repair ability of double-layered hydrogel nerve conduit loaded with DHF	1389:1463	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	8	27	theme	conduit	1441:1447	arg1	comparable					1468:1477	comparable	1468:1477	comparable	1468:1477	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	0	28	theme	Nerve	89:93	arg1	Repairing					95:103	Peripheral Nerve Repairing	78:103	Peripheral Nerve Repairing	78:103	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
35396930	1	29	from	challenge	171:179	arg1	practice					193:200	clinical practice	184:200	clinical practice	184:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	5	30	theme	double-layer	946:957	arg1	conduit					984:990	a double-layer composite hydrogel nerve conduit	944:990	a double-layer composite hydrogel nerve conduit	944:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	2	31	theme	nutrient	404:411	arg1	transport					413:421	nutrient transport	404:421	nutrient transport	404:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	32	theme	migration	390:398	arg1	limitation					371:380	the limitation	367:380	the limitation of cell migration and nutrient transport	367:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	0	33	theme	Multifunctional	0:14	arg1	Conduit					48:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
35396930	1	34	theme	Peripheral	106:115	arg1	recovery					151:158	functional recovery	140:158	functional recovery	140:158	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	34	theme	Peripheral	106:115	arg1	challenge					171:179	a major challenge	163:179	a major challenge in clinical practice	163:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	34	theme	Peripheral	106:115	arg1	regeneration					123:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	6	35	theme	activity	1142:1149	arg1	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	0	36	theme	Composite	29:37	arg1	Conduit					48:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
35396930	3	37	theme	Schiff	546:551	arg1	reaction					558:565	the Schiff base reaction	542:565	the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO	542:710	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	7	38	theme	hydrogel	1259:1266	arg1	conduit					1274:1280	the double-layer composite hydrogel nerve conduit	1232:1280	the double-layer composite hydrogel nerve conduit	1232:1280	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	9	39	theme	composite	1563:1571	arg1	conduit					1582:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	3	40	theme	hydrophobic	676:686	arg1	interaction					688:698	the hydrophobic interaction	672:698	the hydrophobic interaction of F127-CHO	672:710	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	41	theme	conductive	501:510	arg1	properties					512:521	injectable, self-healing, and conductive properties	471:521	injectable, self-healing, and conductive properties	471:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	7	42	theme	defect	1218:1223	arg1	model					1225:1229	the rat sciatic nerve defect model	1196:1229	the rat sciatic nerve defect model	1196:1229	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	2	43	theme	nerve	347:351	arg1	repair					353:358	peripheral nerve repair	336:358	peripheral nerve repair due to the limitation of cell migration and nutrient transport	336:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	3	44	theme	base	553:556	arg1	reaction					558:565	the Schiff base reaction	542:565	the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO	542:710	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	45	theme	injectable	471:480	arg1	properties					512:521	injectable, self-healing, and conductive properties	471:521	injectable, self-healing, and conductive properties	471:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	9	46	theme	hydrogel	1573:1580	arg1	conduit					1582:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	7	47	theme	hollow	1359:1364	arg1	conduit					1366:1372	the chitosan hollow conduit	1346:1372	the chitosan hollow conduit	1346:1372	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	7	48	theme	sciatic	1305:1311	arg1	regeneration					1319:1330	sciatic nerve regeneration	1305:1330	sciatic nerve regeneration	1305:1330	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	7	49	theme	rat	1200:1202	arg1	model					1225:1229	the rat sciatic nerve defect model	1196:1229	the rat sciatic nerve defect model	1196:1229	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	6	50	theme	cell	1164:1167	arg1	proliferation					1169:1181	Schwann cell proliferation	1156:1181	Schwann cell proliferation	1156:1181	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	9	51	theme	multifunctional	1534:1548	arg1	conduit					1582:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	this multifunctional double-layer composite hydrogel conduit	1529:1588	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	2	52	theme	hollow	292:297	arg1	conduit					305:311	the traditional hollow nerve conduit	276:311	the traditional hollow nerve conduit	276:311	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	52	theme	hollow	292:297	arg1	satisfactory					320:331	satisfactory	320:331	satisfactory	320:331	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	1	53	theme	clinical	184:191	arg1	practice					193:200	clinical practice	184:200	clinical practice	184:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	5	54	theme	outer	854:858	arg1	conduit					869:875	the outer chitosan conduit	850:875	the outer chitosan conduit	850:875	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	5	55	theme	conductive	826:835	arg1	hydrogel					837:844	The inner conductive hydrogel	816:844	The inner conductive hydrogel	816:844	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	7	56	theme	nerve	1313:1317	arg1	regeneration					1319:1330	sciatic nerve regeneration	1305:1330	sciatic nerve regeneration	1305:1330	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	5	57	theme	base	920:923	arg1	reaction					925:932	the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit	909:990	the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit	909:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	3	58	theme	polyaniline-modified	575:594	arg1	chitosan					610:617	carboxymethyl chitosan	596:617	carboxymethyl chitosan	596:617	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	9	59	theme	great	1594:1598	arg1	potential					1600:1608	great potential	1594:1608	great potential for peripheral nerve repairing	1594:1639	Therefore, this multifunctional double-layer composite hydrogel conduit has great potential for peripheral nerve repairing.					
35396930	6	60	theme	neural	1029:1034	arg1	conduit					1036:1042	The double-layer composite hydrogel neural conduit	993:1042	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF)	993:1081	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	2	61	theme	nerve	258:262	arg1	repair					264:269	peripheral nerve repair	247:269	peripheral nerve repair	247:269	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	6	62	theme	composite	1010:1018	arg1	conduit					1036:1042	The double-layer composite hydrogel neural conduit	993:1042	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF)	993:1081	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	3	63	theme	aldehyde-modified	623:639	arg1	F-127					650:654	aldehyde-modified Pluronic F-127	623:654	aldehyde-modified Pluronic F-127 (F127-CHO)	623:665	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	63	theme	aldehyde-modified	623:639	arg1	F127-CHO					657:664	F127-CHO	657:664	F127-CHO	657:664	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	5	64	theme	composite	959:967	arg1	conduit					984:990	a double-layer composite hydrogel nerve conduit	944:990	a double-layer composite hydrogel nerve conduit	944:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	5	65	theme	nerve	978:982	arg1	conduit					984:990	a double-layer composite hydrogel nerve conduit	944:990	a double-layer composite hydrogel nerve conduit	944:990	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	6	66	theme	degradability	1097:1109	arg1	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	0	67	theme	Peripheral	78:87	arg1	Repairing					95:103	Peripheral Nerve Repairing	78:103	Peripheral Nerve Repairing	78:103	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
35396930	1	68	theme	functional	140:149	arg1	recovery					151:158	functional recovery	140:158	functional recovery	140:158	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	68	theme	functional	140:149	arg1	challenge					171:179	a major challenge	163:179	a major challenge in clinical practice	163:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	68	theme	functional	140:149	arg1	regeneration					123:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	8	69	theme	double-layered	1411:1424	arg1	conduit					1441:1447	double-layered hydrogel nerve conduit	1411:1447	double-layered hydrogel nerve conduit	1411:1447	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	5	70	theme	inner	820:824	arg1	hydrogel					837:844	The inner conductive hydrogel	816:844	The inner conductive hydrogel	816:844	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	8	71	theme	nerve	1435:1439	arg1	conduit					1441:1447	double-layered hydrogel nerve conduit	1411:1447	double-layered hydrogel nerve conduit	1411:1447	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	2	72	from	satisfactory	320:331	arg1	repair					353:358	peripheral nerve repair	336:358	peripheral nerve repair due to the limitation of cell migration and nutrient transport	336:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	6	73	contain	has	1083:1085	arg1	conduit					1036:1042	The double-layer composite hydrogel neural conduit	993:1042	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF)	993:1081	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	6	73	contain	has	1083:1085	arg2	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	7	74	theme	nerve	1268:1272	arg1	conduit					1274:1280	the double-layer composite hydrogel nerve conduit	1232:1280	the double-layer composite hydrogel nerve conduit	1232:1280	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	6	75	theme	Schwann	1156:1162	arg1	proliferation					1169:1181	Schwann cell proliferation	1156:1181	Schwann cell proliferation	1156:1181	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	5	76	theme	chitosan	860:867	arg1	conduit					869:875	the outer chitosan conduit	850:875	the outer chitosan conduit	850:875	The inner conductive hydrogel and the outer chitosan conduit are formed into a whole through the Schiff base reaction to obtain a double-layer composite hydrogel nerve conduit.					
35396930	4	77	theme	conduit	777:783	arg1	cavity					758:763	the cavity	754:763	the cavity of chitosan conduit prepared by electrodeposition	754:813	The conductive hydrogel is injected into the cavity of chitosan conduit prepared by electrodeposition.					
35396930	2	78	theme	cell	385:388	arg1	migration					390:398	cell migration	385:398	cell migration	385:398	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	0	79	theme	Hydrogel	39:46	arg1	Conduit					48:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
35396930	1	80	theme	nerve	117:121	arg1	recovery					151:158	functional recovery	140:158	functional recovery	140:158	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	80	theme	nerve	117:121	arg1	challenge					171:179	a major challenge	163:179	a major challenge in clinical practice	163:200	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	1	80	theme	nerve	117:121	arg1	regeneration					123:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration	106:134	Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice.					
35396930	6	81	theme	antioxidant	1130:1140	arg1	activity					1142:1149	antioxidant activity	1130:1149	antioxidant activity	1130:1149	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	2	82	theme	Nerve	203:207	arg1	treatment					233:241	an effective treatment	220:241	an effective treatment for peripheral nerve repair	220:269	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	82	theme	Nerve	203:207	arg1	conduit					209:215	Nerve conduit	203:215	Nerve conduit	203:215	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	3	83	theme	self-healing	483:494	arg1	properties					512:521	injectable, self-healing, and conductive properties	471:521	injectable, self-healing, and conductive properties	471:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	6	84	theme	biocompatibility	1112:1127	arg1	activity					1183:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity	1087:1190	The double-layer composite hydrogel neural conduit loaded with 7,8-dihydroxyflavone (DHF) has excellent degradability, biocompatibility, antioxidant activity, and Schwann cell proliferation activity.					
35396930	3	85	theme	cross-linked	443:454	arg1	hydrogels					456:464	the double cross-linked hydrogels	432:464	the double cross-linked hydrogels with injectable, self-healing, and conductive properties	432:521	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	8	86	theme	autologous	1490:1499	arg1	transplantation					1501:1515	autologous transplantation	1490:1515	autologous transplantation	1490:1515	Surprisingly, the repair ability of double-layered hydrogel nerve conduit loaded with DHF is comparable to that of autologous transplantation.					
35396930	2	87	theme	transport	413:421	arg1	limitation					371:380	the limitation	367:380	the limitation of cell migration and nutrient transport	367:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	7	88	theme	nerve	1212:1216	arg1	model					1225:1229	the rat sciatic nerve defect model	1196:1229	the rat sciatic nerve defect model	1196:1229	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	2	89	theme	effective	223:231	arg1	treatment					233:241	an effective treatment	220:241	an effective treatment for peripheral nerve repair	220:269	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	2	89	theme	effective	223:231	arg1	conduit					209:215	Nerve conduit	203:215	Nerve conduit	203:215	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	3	90	theme	F127-CHO	703:710	arg1	F-127					650:654	aldehyde-modified Pluronic F-127	623:654	aldehyde-modified Pluronic F-127 (F127-CHO)	623:665	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	90	theme	F127-CHO	703:710	arg1	interaction					688:698	the hydrophobic interaction	672:698	the hydrophobic interaction of F127-CHO	672:710	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	90	theme	F127-CHO	703:710	arg1	chitosan					610:617	carboxymethyl chitosan	596:617	carboxymethyl chitosan	596:617	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	3	90	theme	F127-CHO	703:710	arg1	F127-CHO					657:664	F127-CHO	657:664	F127-CHO	657:664	Herein, the double cross-linked hydrogels with injectable, self-healing, and conductive properties are synthesized by the Schiff base reaction between polyaniline-modified carboxymethyl chitosan and aldehyde-modified Pluronic F-127 (F127-CHO), and the hydrophobic interaction of F127-CHO.					
35396930	2	91	theme	peripheral	336:345	arg1	repair					353:358	peripheral nerve repair	336:358	peripheral nerve repair due to the limitation of cell migration and nutrient transport	336:421	Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair due to the limitation of cell migration and nutrient transport.					
35396930	7	92	theme	chitosan	1350:1357	arg1	conduit					1366:1372	the chitosan hollow conduit	1346:1372	the chitosan hollow conduit	1346:1372	In the rat sciatic nerve defect model, the double-layer composite hydrogel nerve conduit significantly promotes sciatic nerve regeneration compared with the chitosan hollow conduit.					
35396930	0	93	theme	Double-Layer	16:27	arg1	Conduit					48:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit	0:54	Multifunctional Double-Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing.					
37141997	4	0	theme	removal	989:995	arg1	yield					941:945	the highest VFAs yield	924:945	the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%	924:1002	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	3	1	theme	alicyclic	706:714	arg1	CRAM					727:730	CRAM	727:730	CRAM	727:730	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	3	1	theme	alicyclic	706:714	arg1	molecules					716:724	lignin/carboxyl-rich alicyclic molecules	685:724	lignin/carboxyl-rich alicyclic molecules (CRAM)	685:731	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	6	2	theme	alkaline	1298:1305	arg1	pretreatment					1307:1318	the alkaline pretreatment	1294:1318	the alkaline pretreatment	1294:1318	By considering an economical and efficient perspective, this study recommended the alkaline pretreatment for the anaerobic fermentation of RWAS.					
37141997	6	3	theme	anaerobic	1328:1336	arg1	fermentation					1338:1349	the anaerobic fermentation	1324:1349	the anaerobic fermentation of RWAS	1324:1357	By considering an economical and efficient perspective, this study recommended the alkaline pretreatment for the anaerobic fermentation of RWAS.					
37141997	0	4	theme	fatty	73:77	arg1	acids					79:83	enhancing volatile fatty acids	54:83	enhancing volatile fatty acids	54:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	5	theme	acetogenesis	846:857	arg1	processes					859:867	acetogenesis processes	846:867	acetogenesis processes	846:867	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	4	6	theme	solids	970:975	arg1	yield					941:945	the highest VFAs yield	924:945	the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%	924:1002	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	0	7	from	Role	0:3	arg1	acids					79:83	enhancing volatile fatty acids	54:83	enhancing volatile fatty acids	54:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	2	8	theme	methanogenesis	637:650	arg1	process					652:658	the methanogenesis process	633:658	the methanogenesis process	633:658	All pretreatments effectively enhanced the bioconversion of RWAS and consequently promoted the hydrolysis process, which inhibited the methanogenesis process.					
37141997	1	9	theme	alkyl	253:257	arg1	polyglucose					259:269	alkyl polyglucose	253:269	alkyl polyglucose	253:269	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	4	10	theme	volatile	961:968	arg1	solids					970:975	95.06 mg/g volatile solids	950:975	95.06 mg/g volatile solids	950:975	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	4	11	theme	alkaline	895:902	arg1	pretreatment					904:915	alkaline pretreatment	895:915	alkaline pretreatment	895:915	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	1	12	theme	polyglucose	259:269	arg1	pretreatments					277:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	13	theme	refinery	338:345	arg1	waste					347:351	refinery waste	338:351	refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	338:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	14	theme	organics	413:420	arg1	components					422:431	organics components	413:431	organics components	413:431	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	6	15	theme	efficient	1248:1256	arg1	perspective					1258:1268	an economical and efficient perspective	1230:1268	an economical and efficient perspective	1230:1268	By considering an economical and efficient perspective, this study recommended the alkaline pretreatment for the anaerobic fermentation of RWAS.					
37141997	0	16	theme	anaerobic	103:111	arg1	fermentation					113:124	anaerobic fermentation	103:124	anaerobic fermentation of refinery waste activated sludge	103:159	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	17	theme	molecules	716:724	arg1	release					674:680	the release	670:680	the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups	670:798	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	3	18	from	release	674:680	arg1	thermal-PMS					773:783	thermal-PMS	773:783	thermal-PMS	773:783	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	3	18	from	release	674:680	arg1	groups					793:798	APG groups	789:798	APG groups	789:798	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	3	19	theme	substances	759:768	arg1	release					674:680	the release	670:680	the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups	670:798	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	1	20	from	waste	347:351	arg1	production					322:331	volatile fatty acids (VFAs) production	294:331	volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	294:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	5	21	theme	carbohydrates	1183:1195	arg1	enrichment					1046:1055	the enrichment	1042:1055	the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia,	1042:1140	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	21	theme	carbohydrates	1183:1195	arg1	metabolism					1156:1165	increased metabolism	1146:1165	increased metabolism of amino acids, carbohydrates, and nucleotides	1146:1212	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	4	22	theme	mg/g	956:959	arg1	solids					970:975	95.06 mg/g volatile solids	950:975	95.06 mg/g volatile solids	950:975	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	5	23	theme	acids	1176:1180	arg1	enrichment					1046:1055	the enrichment	1042:1055	the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia,	1042:1140	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	23	theme	acids	1176:1180	arg1	metabolism					1156:1165	increased metabolism	1146:1165	increased metabolism of amino acids, carbohydrates, and nucleotides	1146:1212	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	2	24	theme	hydrolysis	597:606	arg1	process					608:614	the hydrolysis process	593:614	the hydrolysis process	593:614	All pretreatments effectively enhanced the bioconversion of RWAS and consequently promoted the hydrolysis process, which inhibited the methanogenesis process.					
37141997	1	25	theme	microbial	434:442	arg1	communities					444:454	microbial communities	434:454	microbial communities	434:454	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	0	26	theme	type	21:24	arg1	Role					0:3	Role	0:3	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids	0:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	27	theme	tannin	752:757	arg1	substances					759:768	tannin substances	752:768	tannin substances	752:768	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	0	28	theme	refinery	129:136	arg1	sludge					154:159	refinery waste activated sludge	129:159	refinery waste activated sludge	129:159	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	1	29	theme	alkaline	197:204	arg1	pretreatments					277:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	0	30	theme	pretreatment	8:19	arg1	type					21:24	pretreatment type and microbial mechanisms	8:49	type	21:24	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	31	theme	-like	732:736	arg1	compounds					738:746	-like compounds	732:746	-like compounds	732:746	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	6	32	theme	RWAS	1354:1357	arg1	fermentation					1338:1349	the anaerobic fermentation	1324:1349	the anaerobic fermentation of RWAS	1324:1357	By considering an economical and efficient perspective, this study recommended the alkaline pretreatment for the anaerobic fermentation of RWAS.					
37141997	4	33	theme	95.06	950:954	arg1	mg/g					956:959	mg/g	956:959	mg/g	956:959	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	0	34	theme	microbial	30:38	arg1	mechanisms					40:49	pretreatment type and microbial mechanisms	8:49	mechanisms	40:49	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	1	35	theme	pretreatments	277:289	arg1	effects					186:192	the effects	182:192	the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	182:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	0	36	theme	activated	144:152	arg1	sludge					154:159	refinery waste activated sludge	129:159	refinery waste activated sludge	129:159	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	5	37	theme	functional	1060:1069	arg1	Soehngenia					1130:1139	Soehngenia	1130:1139	Soehngenia	1130:1139	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	37	theme	functional	1060:1069	arg1	Planococcus					1114:1124	Planococcus	1114:1124	Planococcus	1114:1124	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	37	theme	functional	1060:1069	arg1	bacteria					1096:1103	functional hydrolytic-acidification bacteria	1060:1103	functional hydrolytic-acidification bacteria	1060:1103	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	1	38	theme	thermal	207:213	arg1	pretreatments					277:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	3	39	dep	molecules	716:724	arg1	compounds					738:746	-like compounds	732:746	-like compounds	732:746	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	0	40	theme	waste	138:142	arg1	sludge					154:159	refinery waste activated sludge	129:159	refinery waste activated sludge	129:159	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	5	41	theme	hydrolytic-acidification	1071:1094	arg1	Soehngenia					1130:1139	Soehngenia	1130:1139	Soehngenia	1130:1139	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	41	theme	hydrolytic-acidification	1071:1094	arg1	Planococcus					1114:1124	Planococcus	1114:1124	Planococcus	1114:1124	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	41	theme	hydrolytic-acidification	1071:1094	arg1	bacteria					1096:1103	functional hydrolytic-acidification bacteria	1060:1103	functional hydrolytic-acidification bacteria	1060:1103	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	6	42	theme	economical	1233:1242	arg1	perspective					1258:1268	an economical and efficient perspective	1230:1268	an economical and efficient perspective	1230:1268	By considering an economical and efficient perspective, this study recommended the alkaline pretreatment for the anaerobic fermentation of RWAS.					
37141997	5	43	theme	amino	1170:1174	arg1	acids					1176:1180	amino acids	1170:1180	amino acids	1170:1180	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	1	44	theme	volatile	294:301	arg1	VFAs					316:319	VFAs	316:319	VFAs	316:319	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	44	theme	volatile	294:301	arg1	acids					309:313	volatile fatty acids	294:313	volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	294:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	2	45	theme	RWAS	562:565	arg1	bioconversion					545:557	the bioconversion	541:557	the bioconversion of RWAS	541:565	All pretreatments effectively enhanced the bioconversion of RWAS and consequently promoted the hydrolysis process, which inhibited the methanogenesis process.					
37141997	5	46	theme	bacteria	1096:1103	arg1	enrichment					1046:1055	the enrichment	1042:1055	the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia,	1042:1140	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	46	theme	bacteria	1096:1103	arg1	metabolism					1156:1165	increased metabolism	1146:1165	increased metabolism of amino acids, carbohydrates, and nucleotides	1146:1212	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	0	47	theme	mechanisms	40:49	arg1	Role					0:3	Role	0:3	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids	0:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	1	48	theme	fatty	303:307	arg1	VFAs					316:319	VFAs	316:319	VFAs	316:319	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	48	theme	fatty	303:307	arg1	acids					309:313	volatile fatty acids	294:313	volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	294:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	0	49	theme	sludge	154:159	arg1	fermentation					113:124	anaerobic fermentation	103:124	anaerobic fermentation of refinery waste activated sludge	103:159	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	5	50	theme	increased	1146:1154	arg1	metabolism					1156:1165	increased metabolism	1146:1165	increased metabolism of amino acids, carbohydrates, and nucleotides	1146:1212	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	4	51	theme	%	1002:1002	arg1	solids					970:975	95.06 mg/g volatile solids	950:975	95.06 mg/g volatile solids	950:975	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	4	51	theme	%	1002:1002	arg1	removal					989:995	VS removal	986:995	removal	989:995	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	1	52	theme	acids	309:313	arg1	production					322:331	volatile fatty acids (VFAs) production	294:331	volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	294:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	4	53	theme	VFAs	936:939	arg1	yield					941:945	the highest VFAs yield	924:945	the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%	924:1002	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	1	54	theme	potential	465:473	arg1	improvement					475:485	the potential improvement	461:485	the potential improvement of mechanisms	461:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	55	theme	thermal-peroxymonosulfate	216:240	arg1	pretreatments					277:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments	197:289	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	4	56	theme	highest	928:934	arg1	yield					941:945	the highest VFAs yield	924:945	the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%	924:1002	Among all pretreatments, alkaline pretreatment showed the highest VFAs yield of 95.06 mg/g volatile solids (VS) and VS removal of 17%.					
37141997	1	57	theme	VFAs	388:391	arg1	yield					393:397	VFAs yield	388:397	VFAs yield	388:397	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	58	from	effects	186:192	arg1	production					322:331	volatile fatty acids (VFAs) production	294:331	volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms	294:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	0	59	theme	volatile	64:71	arg1	acids					79:83	enhancing volatile fatty acids	54:83	enhancing volatile fatty acids	54:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	60	theme	APG	789:791	arg1	groups					793:798	APG groups	789:798	APG groups	789:798	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	0	61	theme	enhancing	54:62	arg1	acids					79:83	enhancing volatile fatty acids	54:83	enhancing volatile fatty acids	54:83	Role of pretreatment type and microbial mechanisms on enhancing volatile fatty acids production during anaerobic fermentation of refinery waste activated sludge.					
37141997	3	62	theme	lignin/carboxyl-rich	685:704	arg1	CRAM					727:730	CRAM	727:730	CRAM	727:730	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	3	62	theme	lignin/carboxyl-rich	685:704	arg1	molecules					716:724	lignin/carboxyl-rich alicyclic molecules	685:724	lignin/carboxyl-rich alicyclic molecules (CRAM)	685:731	However, the release of lignin/carboxyl-rich alicyclic molecules (CRAM)-like compounds and tannin substances in thermal-PMS and APG groups significantly influenced the acidogenesis and acetogenesis processes.					
37141997	1	63	theme	mechanisms	490:499	arg1	communities					444:454	microbial communities	434:454	microbial communities	434:454	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	63	theme	mechanisms	490:499	arg1	improvement					475:485	the potential improvement	461:485	the potential improvement of mechanisms	461:499	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	63	theme	mechanisms	490:499	arg1	composition					400:410	composition	400:410	composition	400:410	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	63	theme	mechanisms	490:499	arg1	components					422:431	organics components	413:431	organics components	413:431	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	1	63	theme	mechanisms	490:499	arg1	yield					393:397	VFAs yield	388:397	VFAs yield	388:397	This study compared the effects of alkaline, thermal, thermal-peroxymonosulfate (PMS), and alkyl polyglucose (APG) pretreatments on volatile fatty acids (VFAs) production from refinery waste activated sludge (RWAS), including VFAs yield, composition, organics components, microbial communities, and the potential improvement of mechanisms.					
37141997	5	64	theme	nucleotides	1202:1212	arg1	enrichment					1046:1055	the enrichment	1042:1055	the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia,	1042:1140	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
37141997	5	64	theme	nucleotides	1202:1212	arg1	metabolism					1156:1165	increased metabolism	1146:1165	increased metabolism of amino acids, carbohydrates, and nucleotides	1146:1212	This result could be associated with the enrichment of functional hydrolytic-acidification bacteria, such as Planococcus and Soehngenia, and increased metabolism of amino acids, carbohydrates, and nucleotides.					
36029210	0	0	theme	Model	69:73	arg1	Development					75:85	Model Development	69:85	Model Development	69:85	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease.					
36029210	2	1	theme	cellular	448:455	arg1	differentiation					457:471	enhanced cellular differentiation	439:471	enhanced cellular differentiation	439:471	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	4	2	from	epithelium	750:759	arg1	HLOs					779:782	alginate-grown HLOs	764:782	alginate-grown HLOs	764:782	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	1	3	theme	tissue	214:219	arg1	structure					221:229	modeling native organ tissue structure	192:229	modeling native organ tissue structure	192:229	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	2	4	theme	enhanced	439:446	arg1	differentiation					457:471	enhanced cellular differentiation	439:471	enhanced cellular differentiation	439:471	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	7	5	theme	cells	1432:1436	arg1	expression					1366:1375	increased expression	1356:1375	increased expression of IPF markers	1356:1390	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	5	theme	cells	1432:1436	arg1	numbers					1407:1413	decreased numbers	1397:1413	decreased numbers of alveolar-like cells	1397:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	5	theme	cells	1432:1436	arg1	increase					1324:1331	an increase	1321:1331	an increase in mesenchymal growth	1321:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	4	6	theme	basal	843:847	arg1	cells					849:853	airway basal cells	836:853	airway basal cells lining the basal lamina	836:877	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	6	7	theme	transforming	1225:1236	arg1	factor					1245:1250	transforming growth factor β	1225:1252	transforming growth factor β (TGFβ)	1225:1259	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	7	theme	transforming	1225:1236	arg1	TGFβ					1255:1258	TGFβ	1255:1258	TGFβ	1255:1258	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	4	8	with	epithelium	820:829	arg1	cells					849:853	airway basal cells	836:853	airway basal cells lining the basal lamina	836:877	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	4	9	theme	cells	911:915	arg1	surface					900:906	the apical surface	889:906	the apical surface of cells on the exterior of the organoid	889:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	5	10	located	present	1047:1053	arg1	cultures					1067:1074	alginate cultures	1058:1074	alginate cultures	1058:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	5	10	located	present	1047:1053	arg2	overgrowth					1023:1032	mesenchymal overgrowth	1011:1032	mesenchymal overgrowth that was not present in alginate cultures	1011:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	6	11	theme	growth	1238:1243	arg1	factor					1245:1250	transforming growth factor β	1225:1252	transforming growth factor β (TGFβ)	1225:1259	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	11	theme	growth	1238:1243	arg1	TGFβ					1255:1258	TGFβ	1255:1258	TGFβ	1255:1258	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	12	with	treatment	1210:1218	arg1	factor					1245:1250	transforming growth factor β	1225:1252	transforming growth factor β (TGFβ)	1225:1259	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	12	with	treatment	1210:1218	arg1	TGFβ					1255:1258	TGFβ	1255:1258	TGFβ	1255:1258	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	4	13	from	cells	911:915	arg1	exterior					924:931	the exterior	920:931	the exterior of the organoid	920:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	3	14	theme	MUC5AC+	667:673	arg1	cells					687:691	MUC5AC+ goblet-like cells	667:691	MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel	667:743	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	4	15	from	exterior	924:931	arg1	surface					900:906	the apical surface	889:906	the apical surface of cells on the exterior of the organoid	889:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	7	16	theme	markers	1384:1390	arg1	expression					1366:1375	increased expression	1356:1375	increased expression of IPF markers	1356:1390	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	16	theme	markers	1384:1390	arg1	numbers					1407:1413	decreased numbers	1397:1413	decreased numbers of alveolar-like cells	1397:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	16	theme	markers	1384:1390	arg1	increase					1324:1331	an increase	1321:1331	an increase in mesenchymal growth	1321:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	3	17	from	onset	583:587	arg1	number					609:614	the number	605:614	the number of multiciliated cells	605:637	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	1	18	theme	cellular	232:239	arg1	composition					241:251	cellular composition	232:251	cellular composition	232:251	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	7	19	theme	alveolar-like	1418:1430	arg1	cells					1432:1436	alveolar-like cells	1418:1436	alveolar-like cells	1418:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	5	20	theme	alginate	1058:1065	arg1	cultures					1067:1074	alginate cultures	1058:1074	alginate cultures	1058:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	7	21	theme	IPF	1380:1382	arg1	markers					1384:1390	IPF markers	1380:1390	IPF markers	1380:1390	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	5	22	attach	present	1047:1053	arg1	cultures					1067:1074	alginate cultures	1058:1074	alginate cultures	1058:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	5	22	attach	present	1047:1053	arg2	overgrowth					1023:1032	mesenchymal overgrowth	1011:1032	mesenchymal overgrowth that was not present in alginate cultures	1011:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	8	23	theme	diseased	1567:1574	arg1	states					1576:1581	diseased states	1567:1581	diseased states such as IPF	1567:1593	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	8	23	theme	diseased	1567:1574	arg1	IPF					1591:1593	IPF	1591:1593	IPF	1591:1593	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	7	24	from	numbers	1407:1413	arg1	growth					1348:1353	mesenchymal growth	1336:1353	mesenchymal growth	1336:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	5	25	from	present	1047:1053	arg1	cultures					1067:1074	alginate cultures	1058:1074	alginate cultures	1058:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	4	26	theme	pseudostratified	803:818	arg1	epithelium					820:829	a pseudostratified epithelium	801:829	a pseudostratified epithelium with airway basal cells lining the basal lamina	801:877	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	2	27	theme	defined	394:400	arg1	substrate					420:428	a fully defined nonanimal product substrate	386:428	a fully defined nonanimal product substrate	386:428	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	2	27	theme	defined	394:400	arg1	alginate					376:383	alginate	376:383	alginate	376:383	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	3	28	from	increase	593:600	arg1	number					609:614	the number	605:614	the number of multiciliated cells	605:637	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	2	29	theme	stem	353:356	arg1	cells					358:362	human pluripotent stem cells	335:362	human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate,	335:429	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	0	30	theme	Lung	6:9	arg1	Culture					20:26	Human Lung Organoid Culture	0:26	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	0:97	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease.					
36029210	8	31	theme	mesenchyme	1508:1517	arg1	interaction					1489:1499	the interaction	1485:1499	the interaction of the mesenchyme with the epithelium	1485:1537	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	4	32	theme	airway	836:841	arg1	cells					849:853	airway basal cells	836:853	airway basal cells lining the basal lamina	836:877	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	4	33	theme	basal	866:870	arg1	lamina					872:877	the basal lamina	862:877	the basal lamina	862:877	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	2	34	theme	pluripotent	341:351	arg1	cells					358:362	human pluripotent stem cells	335:362	human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate,	335:429	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	0	35	theme	Human	0:4	arg1	Culture					20:26	Human Lung Organoid Culture	0:26	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	0:97	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease.					
36029210	2	36	dep	defined	394:400	arg1	nonanimal					402:410	nonanimal	402:410	nonanimal	402:410	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	7	37	from	increase	1324:1331	arg1	growth					1348:1353	mesenchymal growth	1336:1353	mesenchymal growth	1336:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	1	38	theme	human	154:158	arg1	development					165:175	human lung development	154:175	human lung development	154:175	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	8	39	theme	culture	1444:1450	arg1	system					1452:1457	This culture system	1439:1457	This culture system	1439:1457	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	7	40	theme	morphological	1289:1301	arg1	expression					1366:1375	increased expression	1356:1375	increased expression of IPF markers	1356:1390	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	40	theme	morphological	1289:1301	arg1	changes					1303:1309	morphological changes	1289:1309	morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells	1289:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	40	theme	morphological	1289:1301	arg1	increase					1324:1331	an increase	1321:1331	an increase in mesenchymal growth	1321:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	40	theme	morphological	1289:1301	arg1	numbers					1407:1413	decreased numbers	1397:1413	decreased numbers of alveolar-like cells	1397:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	4	41	theme	organoid	940:947	arg1	exterior					924:931	the exterior	920:931	the exterior of the organoid	920:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	1	42	theme	lung	160:163	arg1	development					165:175	human lung development	154:175	human lung development	154:175	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	0	43	theme	Organoid	11:18	arg1	Culture					20:26	Human Lung Organoid Culture	0:26	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	0:97	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease.					
36029210	2	44	theme	available	521:529	arg1	Matrigel					531:538	the commercially available Matrigel	504:538	the commercially available Matrigel	504:538	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	4	45	from	surface	900:906	arg1	exterior					924:931	the exterior	920:931	the exterior of the organoid	920:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	6	46	theme	mesenchyme	1100:1109	arg1	containment					1081:1091	The containment	1077:1091	The containment of the mesenchyme within HLOs in alginate	1077:1133	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	1	47	theme	development	165:175	arg1	study					145:149	the study	141:149	the study of human lung development and disease	141:187	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	1	48	theme	cellular	258:265	arg1	organization					267:278	cellular organization	258:278	cellular organization	258:278	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	3	49	theme	multiciliated	619:631	arg1	cells					633:637	multiciliated cells	619:637	multiciliated cells	619:637	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	7	50	theme	mesenchymal	1336:1346	arg1	growth					1348:1353	mesenchymal growth	1336:1353	mesenchymal growth	1336:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	2	51	theme	human	335:339	arg1	cells					358:362	human pluripotent stem cells	335:362	human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate,	335:429	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	4	52	theme	apical	893:898	arg1	surface					900:906	the apical surface	889:906	the apical surface of cells on the exterior of the organoid	889:947	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	7	53	theme	TGFβ	1262:1265	arg1	treatment					1267:1275	TGFβ treatment	1262:1275	TGFβ treatment	1262:1275	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	3	54	theme	earlier	575:581	arg1	onset					583:587	an earlier onset	572:587	an earlier onset	572:587	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	6	55	from	containment	1081:1091	arg1	alginate					1126:1133	alginate	1126:1133	alginate	1126:1133	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	1	56	theme	disease	181:187	arg1	study					145:149	the study	141:149	the study of human lung development and disease	141:187	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	4	57	dep	cells	849:853	arg1	lining					855:860	lining	855:860	lining	855:860	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	6	58	theme	fibrosis	1192:1199	arg1	features					1159:1166	key features	1155:1166	key features of idiopathic pulmonary fibrosis (IPF)	1155:1205	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	7	59	theme	decreased	1397:1405	arg1	numbers					1407:1413	decreased numbers	1397:1413	decreased numbers of alveolar-like cells	1397:1436	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	1	60	theme	Human	100:104	arg1	organoids					111:119	Human lung organoids	100:119	Human lung organoids (HLOs)	100:126	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	1	60	theme	Human	100:104	arg1	HLOs					122:125	HLOs	122:125	HLOs	122:125	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	2	61	theme	product	412:418	arg1	substrate					420:428	a fully defined nonanimal product substrate	386:428	a fully defined nonanimal product substrate	386:428	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	2	61	theme	product	412:418	arg1	alginate					376:383	alginate	376:383	alginate	376:383	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	8	62	theme	lung	1546:1549	arg1	development					1551:1561	lung development	1546:1561	lung development	1546:1561	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	0	63	from	Culture	20:26	arg1	Alginate					31:38	Alginate	31:38	Alginate	31:38	Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease.					
36029210	6	64	theme	pulmonary	1182:1190	arg1	fibrosis					1192:1199	idiopathic pulmonary fibrosis	1171:1199	idiopathic pulmonary fibrosis (IPF)	1171:1205	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	64	theme	pulmonary	1182:1190	arg1	IPF					1202:1204	IPF	1202:1204	IPF	1202:1204	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	1	65	theme	lung	106:109	arg1	organoids					111:119	Human lung organoids	100:119	Human lung organoids (HLOs)	100:126	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	1	65	theme	lung	106:109	arg1	HLOs					122:125	HLOs	122:125	HLOs	122:125	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	6	66	theme	key	1155:1157	arg1	features					1159:1166	key features	1155:1166	key features of idiopathic pulmonary fibrosis (IPF)	1155:1205	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	67	theme	idiopathic	1171:1180	arg1	fibrosis					1192:1199	idiopathic pulmonary fibrosis	1171:1199	idiopathic pulmonary fibrosis (IPF)	1171:1205	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	6	67	theme	idiopathic	1171:1180	arg1	IPF					1202:1204	IPF	1202:1204	IPF	1202:1204	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	7	68	from	expression	1366:1375	arg1	growth					1348:1353	mesenchymal growth	1336:1353	mesenchymal growth	1336:1353	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	7	69	theme	increased	1356:1364	arg1	expression					1366:1375	increased expression	1356:1375	increased expression of IPF markers	1356:1390	TGFβ treatment resulted in morphological changes including an increase in mesenchymal growth, increased expression of IPF markers, and decreased numbers of alveolar-like cells.					
36029210	3	70	located	observed	707:714	arg1	HLOs					719:722	HLOs	719:722	HLOs cultured in Matrigel	719:743	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	3	70	located	observed	707:714	arg2	cells					687:691	MUC5AC+ goblet-like cells	667:691	MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel	667:743	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	3	71	theme	cells	633:637	arg1	number					609:614	the number	605:614	the number of multiciliated cells	605:637	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	5	72	theme	mesenchymal	1011:1021	arg1	overgrowth					1023:1032	mesenchymal overgrowth	1011:1032	mesenchymal overgrowth that was not present in alginate cultures	1011:1074	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	1	73	theme	modeling	192:199	arg1	structure					221:229	modeling native organ tissue structure	192:229	modeling native organ tissue structure	192:229	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	6	74	theme	features	1159:1166	arg1	modeling					1143:1150	modeling	1143:1150	modeling of key features of idiopathic pulmonary fibrosis (IPF)	1143:1205	The containment of the mesenchyme within HLOs in alginate enabled modeling of key features of idiopathic pulmonary fibrosis (IPF) by treatment with transforming growth factor β (TGFβ).					
36029210	8	75	with	interaction	1489:1499	arg1	epithelium					1528:1537	the epithelium	1524:1537	the epithelium	1524:1537	This culture system provides a model to study the interaction of the mesenchyme with the epithelium during lung development and diseased states such as IPF.					
36029210	1	76	theme	native	201:206	arg1	structure					221:229	modeling native organ tissue structure	192:229	modeling native organ tissue structure	192:229	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36029210	2	77	attach	derived	322:328	arg2	HLOs					317:320	HLOs	317:320	HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate,	317:429	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	2	77	attach	derived	322:328	arg1	cells					358:362	human pluripotent stem cells	335:362	human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate,	335:429	In this report, we demonstrate that HLOs derived from human pluripotent stem cells cultured in alginate, a fully defined nonanimal product substrate, exhibit enhanced cellular differentiation compared with HLOs cultured in the commercially available Matrigel.					
36029210	4	78	theme	alginate-grown	764:777	arg1	HLOs					779:782	alginate-grown HLOs	764:782	alginate-grown HLOs	764:782	The epithelium in alginate-grown HLOs was organized in a pseudostratified epithelium with airway basal cells lining the basal lamina, but with the apical surface of cells on the exterior of the organoid.					
36029210	3	79	theme	goblet-like	675:685	arg1	cells					687:691	MUC5AC+ goblet-like cells	667:691	MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel	667:743	More specifically, we observed an earlier onset and increase in the number of multiciliated cells, along with mucus producing MUC5AC+ goblet-like cells that were not observed in HLOs cultured in Matrigel.					
36029210	5	80	from	cultures	1067:1074	arg1	present					1047:1053	present	1047:1053	present	1047:1053	We further observed that HLOs cultured in Matrigel exhibited mesenchymal overgrowth that was not present in alginate cultures.					
36029210	1	81	theme	organ	208:212	arg1	structure					221:229	modeling native organ tissue structure	192:229	modeling native organ tissue structure	192:229	Human lung organoids (HLOs) are enabling the study of human lung development and disease by modeling native organ tissue structure, cellular composition, and cellular organization.					
36690231	8	0	theme	clinical	1576:1583	arg1	dressing					1591:1598	versatile clinical wound dressing	1566:1598	versatile clinical wound dressing	1566:1598	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	4	1	theme	liver	763:767	arg1	model					776:780	the liver injury model	759:780	the liver injury model	759:780	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	2	theme	mechanical	647:656	arg1	properties					658:667	The mechanical properties	643:667	The mechanical properties (compressive strength of 100 kPa)	643:701	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	0	3	theme	hemostatic	117:126	arg1	properties					128:137	efficient antibacterial and hemostatic properties	89:137	efficient antibacterial and hemostatic properties	89:137	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	1	4	theme	hemostatic	211:220	arg1	properties					240:249	hemostatic and antibacterial properties	211:249	hemostatic and antibacterial properties	211:249	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	7	5	theme	IL-6	1424:1427	arg1	expression					1410:1419	the expression	1406:1419	the expression of IL-6	1406:1427	Immunofluorescence staining assays revealed that the composite sponge reduced inflammation by downregulating the expression of IL-6 and enhanced angiogenesis by upregulating VEGF expression.					
36690231	5	6	from	residues	941:948	arg1	sericin					953:959	sericin	953:959	sericin	953:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	5	7	theme	"	982:982	arg1	way					984:986	a "one-step, green" way	964:986	a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)	964:1118	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	4	8	theme	hemostasis	728:737	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	7	9	theme	Immunofluorescence	1297:1314	arg1	assays					1325:1330	Immunofluorescence staining assays	1297:1330	Immunofluorescence staining assays	1297:1330	Immunofluorescence staining assays revealed that the composite sponge reduced inflammation by downregulating the expression of IL-6 and enhanced angiogenesis by upregulating VEGF expression.					
36690231	1	10	with	dressings	196:204	arg1	properties					240:249	hemostatic and antibacterial properties	211:249	hemostatic and antibacterial properties	211:249	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	5	11	from	nature	922:927	arg1	sericin					953:959	sericin	953:959	sericin	953:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	5	12	theme	tyrosine	932:939	arg1	residues					941:948	tyrosine residues	932:948	tyrosine residues in sericin	932:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	5	13	dep	way	984:986	arg1	enhance					991:997	enhance	991:997	to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)	988:1118	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	4	14	from	model	816:820	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	2	15	theme	substance	336:344	arg1	sponge					346:351	a multi-functional natural substance sponge	309:351	a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT)	309:469	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	2	15	theme	substance	336:344	arg1	CMC/Ser-Ag/HNT					354:367	CMC/Ser-Ag/HNT	354:367	CMC/Ser-Ag/HNT	354:367	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	4	16	from	time	739:742	arg1	model					776:780	the liver injury model	759:780	the liver injury model	759:780	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	16	from	time	739:742	arg1	model					816:820	the caudal injury model	798:820	the caudal injury model	798:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	3	17	theme	CMC/Ser-Ag/HNT	472:485	arg1	sponge					487:492	CMC/Ser-Ag/HNT sponge	472:492	CMC/Ser-Ag/HNT sponge	472:492	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	0	18	theme	wound	156:160	arg1	healing					162:168	wound healing	156:168	wound healing	156:168	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	5	19	theme	residues	941:948	arg1	nature					922:927	the redox nature	912:927	the redox nature of tyrosine residues in sericin	912:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	2	20	theme	natural	328:334	arg1	sponge					346:351	a multi-functional natural substance sponge	309:351	a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT)	309:469	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	2	20	theme	natural	328:334	arg1	CMC/Ser-Ag/HNT					354:367	CMC/Ser-Ag/HNT	354:367	CMC/Ser-Ag/HNT	354:367	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	8	21	theme	CMC/Ser-Ag/HNT	1541:1554	arg1	sponge					1556:1561	CMC/Ser-Ag/HNT sponge	1541:1561	CMC/Ser-Ag/HNT sponge	1541:1561	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	1	22	theme	antibacterial	226:238	arg1	properties					240:249	hemostatic and antibacterial properties	211:249	hemostatic and antibacterial properties	211:249	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	0	23	theme	carboxymethyl	17:29	arg1	chitosan/sericin					31:46	Multi-functional carboxymethyl chitosan/sericin	0:46	Multi-functional carboxymethyl chitosan/sericin	0:46	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	8	24	theme	hemorrhagic	1616:1626	arg1	wounds					1641:1646	hemorrhagic and infected wounds	1616:1646	wounds	1641:1646	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	6	25	theme	collagen	1277:1284	arg1	formation					1286:1294	collagen formation	1277:1294	collagen formation	1277:1294	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	6	26	theme	full-thickness	1142:1155	arg1	model					1169:1173	the rat full-thickness skin defect model	1134:1173	the rat full-thickness skin defect model experiments	1134:1185	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	7	27	theme	staining	1316:1323	arg1	assays					1325:1330	Immunofluorescence staining assays	1297:1330	Immunofluorescence staining assays	1297:1330	Immunofluorescence staining assays revealed that the composite sponge reduced inflammation by downregulating the expression of IL-6 and enhanced angiogenesis by upregulating VEGF expression.					
36690231	0	28	theme	Multi-functional	0:15	arg1	chitosan/sericin					31:46	Multi-functional carboxymethyl chitosan/sericin	0:46	Multi-functional carboxymethyl chitosan/sericin	0:46	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	5	29	theme	one-step	967:974	arg1	way					984:986	a "one-step, green" way	964:986	a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)	964:1118	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	5	30	theme	redox	916:920	arg1	nature					922:927	the redox nature	912:927	the redox nature of tyrosine residues in sericin	912:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	8	31	theme	infected	1632:1639	arg1	wounds					1641:1646	hemorrhagic and infected wounds	1616:1646	wounds	1641:1646	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	5	32	from	sericin	953:959	arg1	nature					922:927	the redox nature	912:927	the redox nature of tyrosine residues in sericin	912:959	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	4	33	theme	injury	809:814	arg1	model					816:820	the caudal injury model	798:820	the caudal injury model	798:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	34	dep	capacity	718:725	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	7	35	theme	composite	1350:1358	arg1	sponge					1360:1365	the composite sponge	1346:1365	the composite sponge	1346:1365	Immunofluorescence staining assays revealed that the composite sponge reduced inflammation by downregulating the expression of IL-6 and enhanced angiogenesis by upregulating VEGF expression.					
36690231	6	36	theme	rat	1138:1140	arg1	model					1169:1173	the rat full-thickness skin defect model	1134:1173	the rat full-thickness skin defect model experiments	1134:1185	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	3	37	theme	compressive	578:588	arg1	stability					590:598	compressive stability	578:598	compressive stability	578:598	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	8	38	theme	great	1522:1526	arg1	potential					1528:1536	the great potential	1518:1536	the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing	1518:1598	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	3	39	theme	compressive	553:563	arg1	strength					565:572	compressive strength	553:572	compressive strength	553:572	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	5	40	dep	coli	1067:1070	arg1	aureus					1112:1117	S. aureus	1109:1117	S. aureus	1109:1117	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	5	40	dep	coli	1067:1070	arg1	coli					1076:1079	E. coli	1073:1079	E. coli	1073:1079	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	1	41	theme	great	265:269	arg1	attention					271:279	great attention	265:279	great attention	265:279	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	4	42	dep	properties	658:667	arg1	strength					682:689	compressive strength	670:689	compressive strength of 100 kPa	670:700	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	43	theme	CMC	865:867	arg1	sponge					869:874	the CMC sponge	861:874	the CMC sponge	861:874	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	0	44	theme	composite	67:75	arg1	sponge					77:82	composite sponge	67:82	composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing	67:168	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	3	45	contain	bear	514:517	arg2	porosity					543:550	porosity	543:550	porosity	543:550	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg2	stability					590:598	compressive stability	578:598	compressive stability	578:598	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg1	sponge					487:492	CMC/Ser-Ag/HNT sponge	472:492	CMC/Ser-Ag/HNT sponge	472:492	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg2	cytocompatibility					601:617	cytocompatibility	601:617	cytocompatibility	601:617	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg2	strength					565:572	compressive strength	553:572	compressive strength	553:572	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg2	hemocompatibility					624:640	hemocompatibility	624:640	hemocompatibility	624:640	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	3	45	contain	bear	514:517	arg2	hygroscopicity					527:540	desired hygroscopicity	519:540	desired hygroscopicity	519:540	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	5	46	theme	hybrid	1033:1038	arg1	sponge					1040:1045	the hybrid sponge	1029:1045	the hybrid sponge	1029:1045	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	4	47	theme	hemostatic	707:716	arg1	capacity					718:725	hemostatic capacity	707:725	hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model)	707:821	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	0	48	theme	efficient	89:97	arg1	properties					128:137	efficient antibacterial and hemostatic properties	89:137	efficient antibacterial and hemostatic properties	89:137	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	5	49	theme	sponge	1040:1045	arg1	activity					1017:1024	the antibacterial activity	999:1024	the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)	999:1118	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	6	50	theme	model	1169:1173	arg1	experiments					1175:1185	the rat full-thickness skin defect model experiments	1134:1185	the rat full-thickness skin defect model experiments	1134:1185	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	4	51	theme	compressive	670:680	arg1	strength					682:689	compressive strength	670:689	compressive strength of 100 kPa	670:700	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	5	52	dep	one-step	967:974	arg1	green					977:981	green	977:981	green	977:981	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	8	53	theme	sponge	1556:1561	arg1	potential					1528:1536	the great potential	1518:1536	the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing	1518:1598	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	1	54	theme	dressings	196:204	arg1	development					175:185	The development	171:185	The development of wound dressings with hemostatic and antibacterial properties	171:249	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	4	55	theme	injury	769:774	arg1	model					776:780	the liver injury model	759:780	the liver injury model	759:780	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	56	from	12 ± 3 s	786:793	arg1	model					776:780	the liver injury model	759:780	the liver injury model	759:780	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	56	from	12 ± 3 s	786:793	arg1	model					816:820	the caudal injury model	798:820	the caudal injury model	798:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	6	57	theme	CMC/Ser-Ag/HNT4	1209:1223	arg1	sponge					1225:1230	the CMC/Ser-Ag/HNT4 sponge	1205:1230	the CMC/Ser-Ag/HNT4 sponge	1205:1230	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	2	58	theme	multi-functional	311:326	arg1	sponge					346:351	a multi-functional natural substance sponge	309:351	a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT)	309:469	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	2	58	theme	multi-functional	311:326	arg1	CMC/Ser-Ag/HNT					354:367	CMC/Ser-Ag/HNT	354:367	CMC/Ser-Ag/HNT	354:367	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	4	59	theme	15 ± 3 s	747:754	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	3	60	theme	desired	519:525	arg1	hygroscopicity					527:540	desired hygroscopicity	519:540	desired hygroscopicity	519:540	CMC/Ser-Ag/HNT sponge was demonstrated to bear desired hygroscopicity, porosity, compressive strength and compressive stability, cytocompatibility, and hemocompatibility.					
36690231	7	61	theme	VEGF	1471:1474	arg1	expression					1476:1485	VEGF expression	1471:1485	VEGF expression	1471:1485	Immunofluorescence staining assays revealed that the composite sponge reduced inflammation by downregulating the expression of IL-6 and enhanced angiogenesis by upregulating VEGF expression.					
36690231	6	62	theme	skin	1157:1160	arg1	model					1169:1173	the rat full-thickness skin defect model	1134:1173	the rat full-thickness skin defect model experiments	1134:1185	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	8	63	theme	versatile	1566:1574	arg1	dressing					1591:1598	versatile clinical wound dressing	1566:1598	versatile clinical wound dressing	1566:1598	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	5	64	theme	antibacterial	1003:1015	arg1	activity					1017:1024	the antibacterial activity	999:1024	the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)	999:1118	Ser-Ag was synthesized in situ via the redox nature of tyrosine residues in sericin in a "one-step, green" way to enhance the antibacterial activity of the hybrid sponge against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).					
36690231	4	65	theme	caudal	802:807	arg1	model					816:820	the caudal injury model	798:820	the caudal injury model	798:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	2	66	theme	carboxymethyl	382:394	arg1	CMC					406:408	CMC	406:408	CMC	406:408	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	2	66	theme	carboxymethyl	382:394	arg1	chitosan					396:403	carboxymethyl chitosan	382:403	carboxymethyl chitosan (CMC)	382:409	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	4	67	from	model	776:780	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	68	theme	12 ± 3 s	786:793	arg1	time					739:742	hemostasis time	728:742	hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model	728:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	69	from	15 ± 3 s	747:754	arg1	model					776:780	the liver injury model	759:780	the liver injury model	759:780	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	4	69	from	15 ± 3 s	747:754	arg1	model					816:820	the caudal injury model	798:820	the caudal injury model	798:820	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	1	70	theme	wound	190:194	arg1	dressings					196:204	wound dressings	190:204	wound dressings with hemostatic and antibacterial properties	190:249	The development of wound dressings with hemostatic and antibacterial properties has attracted great attention.					
36690231	6	71	theme	defect	1162:1167	arg1	model					1169:1173	the rat full-thickness skin defect model	1134:1173	the rat full-thickness skin defect model experiments	1134:1185	In addition, the rat full-thickness skin defect model experiments demonstrated that the CMC/Ser-Ag/HNT4 sponge significantly promoted epithelialization and collagen formation.					
36690231	4	72	theme	100 kPa	694:700	arg1	strength					682:689	compressive strength	670:689	compressive strength of 100 kPa	670:700	The mechanical properties (compressive strength of 100 kPa) and hemostatic capacity (hemostasis time of 15 ± 3 s in the liver injury model and 12 ± 3 s in the caudal injury model) were enhanced by introducing HNT into the CMC sponge.					
36690231	0	73	theme	antibacterial	99:111	arg1	properties					128:137	efficient antibacterial and hemostatic properties	89:137	efficient antibacterial and hemostatic properties	89:137	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	8	74	theme	wound	1585:1589	arg1	dressing					1591:1598	versatile clinical wound dressing	1566:1598	versatile clinical wound dressing	1566:1598	All the findings demonstrated the great potential of CMC/Ser-Ag/HNT sponge as versatile clinical wound dressing, especially for hemorrhagic and infected wounds.					
36690231	0	75	with	sponge	77:82	arg1	properties					128:137	efficient antibacterial and hemostatic properties	89:137	efficient antibacterial and hemostatic properties	89:137	Multi-functional carboxymethyl chitosan/sericin protein/halloysite composite sponge with efficient antibacterial and hemostatic properties for accelerating wound healing.					
36690231	2	76	theme	sericin-silver	412:425	arg1	Ser-Ag					441:446	Ser-Ag	441:446	Ser-Ag	441:446	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
36690231	2	76	theme	sericin-silver	412:425	arg1	nanoparticle					427:438	sericin-silver nanoparticle	412:438	sericin-silver nanoparticle (Ser-Ag)	412:447	In this study, we prepared a multi-functional natural substance sponge (CMC/Ser-Ag/HNT) composed of carboxymethyl chitosan (CMC), sericin-silver nanoparticle (Ser-Ag), and halloysite (HNT).					
35235865	11	0	from	repair	1839:1844	arg1	models					1885:1890	animal models	1878:1890	animal models	1878:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	3	1	contain	has	588:590	arg1	cartilage					578:586	fetal cartilage	572:586	fetal cartilage	572:586	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	3	1	contain	has	588:590	arg2	2.1-times					592:600	2.1-times	592:600	2.1-times	592:600	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	2	2	theme	mature	330:335	arg1	pigs					337:340	fetal, neonatal, juvenile, and mature pigs	299:340	fetal, neonatal, juvenile, and mature pigs	299:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	1	3	theme	developmental	249:261	arg1	stages					263:268	different developmental stages	239:268	different developmental stages	239:268	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	11	4	from	regeneration	1849:1860	arg1	models					1885:1890	animal models	1878:1890	animal models	1878:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	5	5	dep	types	894:898	arg1	types					894:898	collagen types IX, XI, and XIV, and aggrecan	885:928	collagen types IX, XI, and XIV, and aggrecan	885:928	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	5	dep	types	894:898	arg1	XI					904:905	XI	904:905	XI	904:905	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	5	dep	types	894:898	arg1	XIV					912:914	XIV	912:914	XIV	912:914	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	5	dep	types	894:898	arg1	aggrecan					921:928	aggrecan	921:928	aggrecan	921:928	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	5	dep	types	894:898	arg1	IX					900:901	IX	900:901	IX	900:901	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	7	6	theme	biochemical	1071:1081	arg1	measurements					1083:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	3	7	theme	fetal	551:555	arg1	cartilage					557:565	fetal cartilage	551:565	fetal cartilage	551:565	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	9	8	theme	collagen	1423:1430	arg1	types					1432:1436	collagen types IX, XI, and XIV	1423:1452	collagen types IX, XI, and XIV	1423:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	8	theme	collagen	1423:1430	arg1	XI					1442:1443	XI	1442:1443	XI	1442:1443	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	8	theme	collagen	1423:1430	arg1	XIV					1450:1452	XIV	1450:1452	XIV	1450:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	8	theme	collagen	1423:1430	arg1	IX					1438:1439	IX	1438:1439	IX	1438:1439	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	12	9	theme	proteomic	2038:2046	arg1	techniques					2048:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	9	10	theme	significant	1402:1412	arg1	drops					1414:1418	significant drops	1402:1418	significant drops in collagen types IX, XI, and XIV	1402:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	5	11	theme	Proteomics	811:820	arg1	analysis					822:829	Proteomics analysis	811:829	Proteomics analysis	811:829	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	11	12	from	efforts	1824:1830	arg1	critical					1793:1800	critical	1793:1800	critical	1793:1800	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	14	13	theme	bottom-up	2459:2467	arg1	tool					2494:2497	a critical tool	2483:2497	a critical tool in tissue characterization	2483:2524	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	14	13	theme	bottom-up	2459:2467	arg1	proteomics					2469:2478	bottom-up proteomics	2459:2478	bottom-up proteomics	2459:2478	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	3	14	theme	fetal	572:576	arg1	cartilage					578:586	fetal cartilage	572:586	fetal cartilage	572:586	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	1	15	theme	mechanical	177:186	arg1	properties					188:197	its mechanical properties	173:197	its mechanical properties	173:197	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	10	16	theme	glycosaminoglycan	1560:1576	arg1	content					1578:1584	overall glycosaminoglycan content	1552:1584	overall glycosaminoglycan content compared to aggrecan and link protein	1552:1622	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	11	17	theme	tissue	1805:1810	arg1	efforts					1824:1830	tissue engineering efforts	1805:1830	tissue engineering efforts toward repair or regeneration of cartilage in animal models	1805:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	12	18	theme	articular	1962:1970	arg1	cartilage					1972:1980	porcine articular cartilage	1954:1980	porcine articular cartilage	1954:1980	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	12	19	theme	matrix	2105:2110	arg1	composition					2112:2122	extracellular matrix composition	2091:2122	extracellular matrix composition	2091:2122	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	11	20	from	critical	1793:1800	arg1	efforts					1824:1830	tissue engineering efforts	1805:1830	tissue engineering efforts toward repair or regeneration of cartilage in animal models	1805:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	8	21	theme	powerful	1259:1266	arg1	tool					1268:1271	a powerful tool	1257:1271	a powerful tool for tissue characterization	1257:1299	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	8	21	theme	powerful	1259:1266	arg1	proteomics					1236:1245	Bottom-up proteomics	1226:1245	Bottom-up proteomics	1226:1245	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	10	22	theme	link	1611:1614	arg1	protein					1616:1622	link protein	1611:1622	link protein	1611:1622	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	5	23	from	increases	839:847	arg1	types					861:865	collagen types II	852:868	collagen types II	852:868	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	23	from	increases	839:847	arg1	III					874:876	III	874:876	III	874:876	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	11	24	theme	bottom-up	1757:1765	arg1	techniques					1778:1787	bottom-up proteomics techniques	1757:1787	bottom-up proteomics techniques	1757:1787	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	13	25	theme	collagen	2299:2306	arg1	composition					2316:2326	the collagen subtype composition	2295:2326	the collagen subtype composition of the cartilage	2295:2343	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	2	26	from	knees	290:294	arg1	Cartilage					271:279	Cartilage	271:279	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs	271:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	14	27	theme	matrix	2582:2587	arg1	composition					2589:2599	matrix composition	2582:2599	matrix composition	2582:2599	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	7	28	theme	major	1214:1218	arg1	role					1220:1223	a major role	1212:1223	a major role	1212:1223	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	5	29	theme	collagen	885:892	arg1	types					894:898	collagen types IX, XI, and XIV, and aggrecan	885:928	collagen types IX, XI, and XIV, and aggrecan	885:928	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	29	theme	collagen	885:892	arg1	XI					904:905	XI	904:905	XI	904:905	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	29	theme	collagen	885:892	arg1	XIV					912:914	XIV	912:914	XIV	912:914	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	29	theme	collagen	885:892	arg1	aggrecan					921:928	aggrecan	921:928	aggrecan	921:928	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	5	29	theme	collagen	885:892	arg1	IX					900:901	IX	900:901	IX	900:901	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	12	30	theme	extracellular	2091:2103	arg1	composition					2112:2122	extracellular matrix composition	2091:2122	extracellular matrix composition	2091:2122	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	1	31	theme	cartilage	150:158	arg1	development					127:137	the development	123:137	the development of porcine cartilage	123:158	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	6	32	dep	types	971:975	arg1	IX					977:978	IX	977:978	IX	977:978	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	6	32	dep	types	971:975	arg1	types					971:975	collagen types IX and XI	962:985	collagen types IX and XI	962:985	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	6	32	dep	types	971:975	arg1	XI					984:985	XI	984:985	XI	984:985	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	8	33	theme	biochemical	1342:1352	arg1	analysis					1354:1361	routine biochemical analysis	1334:1361	routine biochemical analysis	1334:1361	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	2	34	theme	mechanical	372:381	arg1	testing					383:389	mechanical testing	372:389	mechanical testing	372:389	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	13	35	theme	bottom-up	2185:2193	arg1	approach					2206:2213	a bottom-up proteomics approach	2183:2213	a bottom-up proteomics approach	2183:2213	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	0	36	theme	biochemical	27:37	arg1	characterization					39:54	Proteomic, mechanical, and biochemical characterization	0:54	Proteomic, mechanical, and biochemical characterization of cartilage development.	0:80	Proteomic, mechanical, and biochemical characterization of cartilage development.					
35235865	4	37	theme	juvenile	744:751	arg1	stage					753:757	the juvenile stage	740:757	the juvenile stage	740:757	Tensile and compressive properties peak in the juvenile stage, with a tensile modulus 4.7-times that of neonatal.					
35235865	10	38	theme	non-enzymatic	1633:1645	arg1	degradation					1647:1657	non-enzymatic degradation	1633:1657	non-enzymatic degradation of aggrecan structures	1633:1680	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	0	39	theme	Proteomic	0:8	arg1	characterization					39:54	Proteomic, mechanical, and biochemical characterization	0:54	Proteomic, mechanical, and biochemical characterization of cartilage development.	0:80	Proteomic, mechanical, and biochemical characterization of cartilage development.					
35235865	2	40	theme	fluorophore-assisted	412:431	arg1	electrophoresis					446:460	fluorophore-assisted carbohydrate electrophoresis	412:460	fluorophore-assisted carbohydrate electrophoresis	412:460	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	0	41	theme	mechanical	11:20	arg1	characterization					39:54	Proteomic, mechanical, and biochemical characterization	0:54	Proteomic, mechanical, and biochemical characterization of cartilage development.	0:80	Proteomic, mechanical, and biochemical characterization of cartilage development.					
35235865	13	42	theme	protein	2251:2257	arg1	changes					2259:2265	protein changes	2251:2265	protein changes	2251:2265	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	1	43	theme	work	104:107	arg1	objective					86:94	The objective	82:94	The objective of this work	82:107	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	6	44	dep	mature	1048:1053	arg1	to					1045:1046	to	1045:1046	to	1045:1046	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	10	45	theme	structures	1671:1680	arg1	degradation					1647:1657	non-enzymatic degradation	1633:1657	non-enzymatic degradation of aggrecan structures	1633:1680	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	10	45	theme	structures	1671:1680	arg1	hyaluronan					1685:1694	hyaluronan	1685:1694	hyaluronan in mature cartilage	1685:1714	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	9	46	from	drops	1414:1418	arg1	types					1432:1436	collagen types IX, XI, and XIV	1423:1452	collagen types IX, XI, and XIV	1423:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	46	from	drops	1414:1418	arg1	XI					1442:1443	XI	1442:1443	XI	1442:1443	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	46	from	drops	1414:1418	arg1	XIV					1450:1452	XIV	1450:1452	XIV	1450:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	46	from	drops	1414:1418	arg1	IX					1438:1439	IX	1438:1439	IX	1438:1439	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	0	47	theme	cartilage	59:67	arg1	development					69:79	cartilage development	59:79	cartilage development	59:79	Proteomic, mechanical, and biochemical characterization of cartilage development.					
35235865	9	48	dep	types	1432:1436	arg1	types					1432:1436	collagen types IX, XI, and XIV	1423:1452	collagen types IX, XI, and XIV	1423:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	48	dep	types	1432:1436	arg1	XI					1442:1443	XI	1442:1443	XI	1442:1443	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	48	dep	types	1432:1436	arg1	XIV					1450:1452	XIV	1450:1452	XIV	1450:1452	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	9	48	dep	types	1432:1436	arg1	IX					1438:1439	IX	1438:1439	IX	1438:1439	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	11	49	theme	animal	1878:1883	arg1	models					1885:1890	animal models	1878:1890	animal models	1878:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	7	50	theme	greatest	1107:1114	arg1	changes					1130:1136	their greatest developmental changes	1101:1136	their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role	1101:1223	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	10	51	from	Changes	1541:1547	arg1	content					1578:1584	overall glycosaminoglycan content	1552:1584	overall glycosaminoglycan content compared to aggrecan and link protein	1552:1622	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	7	52	theme	Mechanical	1056:1065	arg1	measurements					1083:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	11	53	theme	tissue	1732:1737	arg1	characterization					1739:1754	tissue characterization	1732:1754	tissue characterization	1732:1754	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	11	54	theme	cartilage	1865:1873	arg1	regeneration					1849:1860	regeneration	1849:1860	regeneration	1849:1860	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	11	54	theme	cartilage	1865:1873	arg1	repair					1839:1844	repair	1839:1844	repair	1839:1844	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	13	55	theme	proteomics	2195:2204	arg1	approach					2206:2213	a bottom-up proteomics approach	2183:2213	a bottom-up proteomics approach	2183:2213	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	14	56	theme	critical	2485:2492	arg1	tool					2494:2497	a critical tool	2483:2497	a critical tool in tissue characterization	2483:2524	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	14	56	theme	critical	2485:2492	arg1	proteomics					2469:2478	bottom-up proteomics	2459:2478	bottom-up proteomics	2459:2478	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	3	57	theme	mature	665:670	arg1	cartilage					672:680	mature cartilage	665:680	mature cartilage	665:680	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	10	58	from	hyaluronan	1685:1694	arg1	cartilage					1706:1714	mature cartilage	1699:1714	mature cartilage	1699:1714	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	2	59	theme	pigs	337:340	arg1	knees					290:294	the knees	286:294	the knees of fetal, neonatal, juvenile, and mature pigs	286:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	1	60	theme	different	239:247	arg1	stages					263:268	different developmental stages	239:268	different developmental stages	239:268	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	2	61	theme	juvenile	316:323	arg1	pigs					337:340	fetal, neonatal, juvenile, and mature pigs	299:340	fetal, neonatal, juvenile, and mature pigs	299:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	10	62	theme	overall	1552:1558	arg1	content					1578:1584	overall glycosaminoglycan content	1552:1584	overall glycosaminoglycan content compared to aggrecan and link protein	1552:1622	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	12	63	theme	biochemical	2021:2031	arg1	techniques					2048:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	3	64	theme	dry	537:539	arg1	weight					541:546	dry weight	537:546	dry weight of fetal cartilage	537:565	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	13	65	theme	cartilage	2335:2343	arg1	composition					2316:2326	the collagen subtype composition	2295:2326	the collagen subtype composition of the cartilage	2295:2343	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	14	66	theme	deeper	2558:2563	arg1	understanding					2565:2577	a deeper understanding	2556:2577	a deeper understanding of matrix composition	2556:2599	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	2	67	theme	neonatal	306:313	arg1	pigs					337:340	fetal, neonatal, juvenile, and mature pigs	299:340	fetal, neonatal, juvenile, and mature pigs	299:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	8	68	theme	Bottom-up	1226:1234	arg1	tool					1268:1271	a powerful tool	1257:1271	a powerful tool for tissue characterization	1257:1299	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	8	68	theme	Bottom-up	1226:1234	arg1	proteomics					1236:1245	Bottom-up proteomics	1226:1245	Bottom-up proteomics	1226:1245	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	2	69	theme	fetal	299:303	arg1	pigs					337:340	fetal, neonatal, juvenile, and mature pigs	299:340	fetal, neonatal, juvenile, and mature pigs	299:340	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	13	70	theme	subtype	2308:2314	arg1	composition					2316:2326	the collagen subtype composition	2295:2326	the collagen subtype composition of the cartilage	2295:2343	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	12	71	theme	biomechanical	2006:2018	arg1	techniques					2048:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	biomechanical, biochemical, and proteomic techniques	2006:2057	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	13	72	dep	types	2411:2415	arg1	IX					2417:2418	IX	2417:2418	IX	2417:2418	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	72	dep	types	2411:2415	arg1	types					2411:2415	collagen types IX, XI, and XIV	2402:2431	collagen types IX, XI, and XIV	2402:2431	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	72	dep	types	2411:2415	arg1	XI					2421:2422	XI	2421:2422	XI	2421:2422	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	72	dep	types	2411:2415	arg1	XIV					2429:2431	XIV	2429:2431	XIV	2429:2431	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	14	73	from	development	2605:2615	arg1	studies					2639:2645	tissue engineering studies	2620:2645	tissue engineering studies	2620:2645	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	11	74	theme	engineering	1812:1822	arg1	efforts					1824:1830	tissue engineering efforts	1805:1830	tissue engineering efforts toward repair or regeneration of cartilage in animal models	1805:1890	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	13	75	theme	collagen	2358:2365	arg1	types					2367:2371	collagen types II	2358:2374	collagen types II	2358:2374	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	5	76	theme	collagen	852:859	arg1	types					861:865	collagen types II	852:868	collagen types II	852:868	Proteomics analysis reveals increases in collagen types II and III, while collagen types IX, XI, and XIV, and aggrecan decrease with age.					
35235865	12	77	theme	porcine	1954:1960	arg1	cartilage					1972:1980	porcine articular cartilage	1954:1980	porcine articular cartilage	1954:1980	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	14	78	theme	tissue	2620:2625	arg1	studies					2639:2645	tissue engineering studies	2620:2645	tissue engineering studies	2620:2645	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	12	79	theme	mature	2145:2150	arg1	cartilage					2152:2160	mature cartilage	2145:2160	mature cartilage	2145:2160	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	13	80	theme	first	2171:2175	arg1	time					2177:2180	the first time	2167:2180	the first time	2167:2180	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	12	81	theme	cartilage	1972:1980	arg1	development					1939:1949	the development	1935:1949	the development of porcine articular cartilage	1935:1980	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	4	82	theme	compressive	709:719	arg1	properties					721:730	Tensile and compressive properties	697:730	Tensile and compressive properties	697:730	Tensile and compressive properties peak in the juvenile stage, with a tensile modulus 4.7-times that of neonatal.					
35235865	3	83	theme	cartilage	557:565	arg1	weight					541:546	dry weight	537:546	dry weight of fetal cartilage	537:565	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	14	84	theme	composition	2589:2599	arg1	development					2605:2615	development	2605:2615	development in tissue engineering studies	2605:2645	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	14	84	theme	composition	2589:2599	arg1	understanding					2565:2577	a deeper understanding	2556:2577	a deeper understanding of matrix composition	2556:2599	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	8	85	theme	tissue	1277:1282	arg1	characterization					1284:1299	tissue characterization	1277:1299	tissue characterization	1277:1299	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	11	86	theme	proteomics	1767:1776	arg1	techniques					1778:1787	bottom-up proteomics techniques	1757:1787	bottom-up proteomics techniques	1757:1787	In addition to tissue characterization, bottom-up proteomics techniques are critical in tissue engineering efforts toward repair or regeneration of cartilage in animal models.					
35235865	0	87	theme	development	69:79	arg1	characterization					39:54	Proteomic, mechanical, and biochemical characterization	0:54	Proteomic, mechanical, and biochemical characterization of cartilage development.	0:80	Proteomic, mechanical, and biochemical characterization of cartilage development.					
35235865	14	88	from	tool	2494:2497	arg1	characterization					2509:2524	tissue characterization	2502:2524	tissue characterization	2502:2524	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	1	89	theme	porcine	142:148	arg1	cartilage					150:158	porcine cartilage	142:158	porcine cartilage	142:158	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	6	90	theme	collagen	962:969	arg1	IX					977:978	IX	977:978	IX	977:978	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	6	90	theme	collagen	962:969	arg1	types					971:975	collagen types IX and XI	962:985	collagen types IX and XI	962:985	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	6	90	theme	collagen	962:969	arg1	XI					984:985	XI	984:985	XI	984:985	For example, collagen types IX and XI decrease 9.4-times and 5.1-times, respectively from fetal to mature.					
35235865	4	91	theme	Tensile	697:703	arg1	properties					721:730	Tensile and compressive properties	697:730	Tensile and compressive properties	697:730	Tensile and compressive properties peak in the juvenile stage, with a tensile modulus 4.7-times that of neonatal.					
35235865	7	92	contain	have	1096:1099	arg2	changes					1130:1136	their greatest developmental changes	1101:1136	their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role	1101:1223	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	7	92	contain	have	1096:1099	arg1	measurements					1083:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements	1056:1094	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	10	93	theme	mature	1699:1704	arg1	cartilage					1706:1714	mature cartilage	1699:1714	mature cartilage	1699:1714	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	7	94	theme	juvenile	1163:1170	arg1	stages					1172:1177	the neonatal and juvenile stages	1146:1177	the neonatal and juvenile stages	1146:1177	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	3	95	contain	has	506:508	arg1	cartilage					496:504	Mature cartilage	489:504	Mature cartilage	489:504	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	3	95	contain	has	506:508	arg2	collagen					524:531	the collagen	520:531	the collagen per dry weight of fetal cartilage	520:565	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	8	96	theme	routine	1334:1340	arg1	analysis					1354:1361	routine biochemical analysis	1334:1361	routine biochemical analysis	1334:1361	Bottom-up proteomics serves as a powerful tool for tissue characterization, showing results beyond those of routine biochemical analysis.					
35235865	1	97	theme	biochemical	200:210	arg1	content					212:218	biochemical content	200:218	biochemical content	200:218	The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages.					
35235865	7	98	theme	neonatal	1150:1157	arg1	stages					1172:1177	the neonatal and juvenile stages	1146:1177	the neonatal and juvenile stages	1146:1177	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	14	99	theme	engineering	2627:2637	arg1	studies					2639:2645	tissue engineering studies	2620:2645	tissue engineering studies	2620:2645	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	13	100	theme	collagen	2402:2409	arg1	IX					2417:2418	IX	2417:2418	IX	2417:2418	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	100	theme	collagen	2402:2409	arg1	types					2411:2415	collagen types IX, XI, and XIV	2402:2431	collagen types IX, XI, and XIV	2402:2431	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	100	theme	collagen	2402:2409	arg1	XI					2421:2422	XI	2421:2422	XI	2421:2422	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	100	theme	collagen	2402:2409	arg1	XIV					2429:2431	XIV	2429:2431	XIV	2429:2431	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	2	101	theme	carbohydrate	433:444	arg1	electrophoresis					446:460	fluorophore-assisted carbohydrate electrophoresis	412:460	fluorophore-assisted carbohydrate electrophoresis	412:460	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	3	102	theme	dry	651:653	arg1	weight					655:660	dry weight	651:660	dry weight of mature cartilage, respectively	651:694	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	2	103	theme	biochemical	392:402	arg1	assays					404:409	biochemical assays	392:409	biochemical assays	392:409	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	7	104	theme	developmental	1116:1128	arg1	changes					1130:1136	their greatest developmental changes	1101:1136	their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role	1101:1223	Mechanical and biochemical measurements have their greatest developmental changes between the neonatal and juvenile stages, where mechanotransduction plays a major role.					
35235865	13	105	theme	changes	2259:2265	arg1	variety					2240:2246	a wide variety	2233:2246	a wide variety of protein changes	2233:2265	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	105	theme	changes	2259:2265	arg1	changes					2259:2265	protein changes	2251:2265	protein changes	2251:2265	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	12	106	theme	SIGNIFICANCE	1906:1917	arg1	STATEMENT					1893:1901	STATEMENT	1893:1901	STATEMENT OF SIGNIFICANCE	1893:1917	STATEMENT OF SIGNIFICANCE: In this study, the development of porcine articular cartilage is interrogated through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.					
35235865	3	107	dep	glycosaminoglycan	621:637	arg1	the					617:619	the	617:619	the	617:619	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	2	108	theme	bottom-up	467:475	arg1	proteomics					477:486	bottom-up proteomics	467:486	bottom-up proteomics	467:486	Cartilage from the knees of fetal, neonatal, juvenile, and mature pigs was analyzed using histology, mechanical testing, biochemical assays, fluorophore-assisted carbohydrate electrophoresis, and bottom-up proteomics.					
35235865	10	109	theme	aggrecan	1662:1669	arg1	structures					1671:1680	aggrecan structures	1662:1680	aggrecan structures	1662:1680	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	13	110	used	used	2218:2221	arg2	approach					2206:2213	a bottom-up proteomics approach	2183:2213	a bottom-up proteomics approach	2183:2213	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	14	111	theme	tissue	2502:2507	arg1	characterization					2509:2524	tissue characterization	2502:2524	tissue characterization	2502:2524	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
35235865	3	112	theme	cartilage	672:680	arg1	weight					655:660	dry weight	651:660	dry weight of mature cartilage, respectively	651:694	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	13	113	theme	wide	2235:2238	arg1	variety					2240:2246	a wide variety	2233:2246	a wide variety of protein changes	2233:2265	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	13	113	theme	wide	2235:2238	arg1	changes					2259:2265	protein changes	2251:2265	protein changes	2251:2265	For the first time, a bottom-up proteomics approach is used to reveal a wide variety of protein changes through aging; for example, the collagen subtype composition of the cartilage increases in collagen types II and III, and decreases in collagen types IX, XI, and XIV.					
35235865	10	114	from	degradation	1647:1657	arg1	cartilage					1706:1714	mature cartilage	1699:1714	mature cartilage	1699:1714	Changes in overall glycosaminoglycan content compared to aggrecan and link protein indicate non-enzymatic degradation of aggrecan structures or hyaluronan in mature cartilage.					
35235865	4	115	theme	tensile	767:773	arg1	modulus					775:781	a tensile modulus	765:781	a tensile modulus	765:781	Tensile and compressive properties peak in the juvenile stage, with a tensile modulus 4.7-times that of neonatal.					
35235865	3	116	theme	Mature	489:494	arg1	cartilage					496:504	Mature cartilage	489:504	Mature cartilage	489:504	Mature cartilage has 2.2-times the collagen per dry weight of fetal cartilage, and fetal cartilage has 2.1-times and 17.9-times the glycosaminoglycan and DNA per dry weight of mature cartilage, respectively.					
35235865	9	117	theme	proteomic	1377:1385	arg1	analysis					1387:1394	proteomic analysis	1377:1394	proteomic analysis	1377:1394	For example, proteomic analysis shows significant drops in collagen types IX, XI, and XIV throughout development, which shows insight into the permanence of cartilage's matrix.					
35235865	14	118	from	understanding	2565:2577	arg1	studies					2639:2645	tissue engineering studies	2620:2645	tissue engineering studies	2620:2645	This analysis shows that bottom-up proteomics is a critical tool in tissue characterization, especially toward developing a deeper understanding of matrix composition and development in tissue engineering studies.					
36413629	0	0	theme	In	116:117	arg1	Capacity					139:146	In Vivo Osteoinductive Capacity	116:146	In Vivo Osteoinductive Capacity	116:146	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	8	1	theme	promising	1625:1633	arg1	candidates					1635:1644	promising candidates	1625:1644	promising candidates for bone tissue regeneration	1625:1673	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	2	2	theme	zinc	623:626	arg1	cations					637:643	zinc divalent cations	623:643	zinc divalent cations	623:643	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	7	3	theme	energy-disperse	1322:1336	arg1	spectroscopy					1344:1355	energy-disperse X-ray spectroscopy	1322:1355	energy-disperse X-ray spectroscopy	1322:1355	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	8	4	theme	bone	1650:1653	arg1	regeneration					1662:1673	bone tissue regeneration	1650:1673	bone tissue regeneration	1650:1673	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	5	5	theme	rabbit	927:932	arg1	model					934:938	a rabbit model	925:938	a rabbit model	925:938	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	8	6	theme	osteoinductive	1566:1579	arg1	activities					1599:1608	osteoinductive and antibacterial activities	1566:1608	osteoinductive and antibacterial activities	1566:1608	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	0	7	theme	Osteoinductive	124:137	arg1	Capacity					139:146	In Vivo Osteoinductive Capacity	116:146	In Vivo Osteoinductive Capacity	116:146	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	7	8	dep	Fourier	1358:1364	arg1	transform					1366:1374	transform	1366:1374	transform infrared spectroscopy	1366:1396	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	4	9	theme	alginate	793:800	arg1	polymers					802:809	Both the PLA and alginate polymers	776:809	polymers	802:809	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	4	9	theme	alginate	793:800	arg1	approved					821:828	approved	821:828	approved	821:828	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	5	10	theme	histological	958:969	arg1	analysis					971:978	histological analysis	958:978	histological analysis	958:978	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	3	11	theme	nontoxic	753:760	arg1	PLA-alginate					762:773	nontoxic PLA-alginate	753:773	nontoxic PLA-alginate	753:773	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	5	12	theme	In	870:871	arg1	capacity					896:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	7	13	theme	emission	1279:1286	arg1	microscopy					1306:1315	field emission scanning electron microscopy	1273:1315	field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature	1273:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	1	14	theme	osteoinductive	366:379	arg1	properties					381:390	osteoinductive properties	366:390	osteoinductive properties	366:390	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	5	15	theme	bone	878:881	arg1	capacity					896:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	7	16	theme	scanning	1288:1295	arg1	microscopy					1306:1315	field emission scanning electron microscopy	1273:1315	field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature	1273:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	1	17	theme	properties	381:390	arg1	lack					358:361	their lack	352:361	their lack of osteoinductive properties and antibacterial functions	352:418	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	7	18	theme	physical	1235:1242	arg1	properties					1244:1253	The scaffolds' physical properties	1220:1253	The scaffolds' physical properties	1220:1253	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	4	19	dep	US	837:838	arg1	Food					840:843	Food	840:843	Food	840:843	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	4	19	dep	US	837:838	arg1	Drug					849:852	Drug	849:852	Drug	849:852	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	7	20	theme	field	1273:1277	arg1	microscopy					1306:1315	field emission scanning electron microscopy	1273:1315	field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature	1273:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	5	21	theme	regeneration	883:894	arg1	capacity					896:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity	870:903	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	0	22	theme	Three-Dimensional-Printed	12:36	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	0	23	dep	In	116:117	arg1	Vivo					119:122	Vivo	119:122	Vivo	119:122	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	3	24	theme	PLA-alginate	762:773	arg1	performance					738:748	the performance	734:748	the performance of nontoxic PLA-alginate	734:773	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	2	25	theme	constructs	456:465	arg1	success					437:443	the success	433:443	the success of the FDM constructs capable of supporting bone regeneration	433:505	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	2	26	theme	divalent	628:635	arg1	cations					637:643	zinc divalent cations	623:643	zinc divalent cations	623:643	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	7	27	theme	swollen	1473:1479	arg1	states					1481:1486	dry and swollen states	1465:1486	dry and swollen states at body temperature	1465:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	6	28	theme	control	1151:1157	arg1	scaffolds					1159:1167	the control scaffolds	1147:1167	the control scaffolds	1147:1167	The scaffolds exhibited antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa, while the control scaffolds could not resist the two microbial species tested.					
36413629	0	29	theme	Polylactic	48:57	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	6	30	theme	antibacterial	1005:1017	arg1	activity					1019:1026	antibacterial activity	1005:1026	antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa	1005:1138	The scaffolds exhibited antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa, while the control scaffolds could not resist the two microbial species tested.					
36413629	7	31	with	microscopy	1306:1315	arg1	measurements					1426:1437	porosity measurements	1417:1437	porosity measurements	1417:1437	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	31	with	microscopy	1306:1315	arg1	absorption					1405:1414	water absorption	1399:1414	water absorption	1399:1414	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	31	with	microscopy	1306:1315	arg1	tests					1456:1460	compression tests	1444:1460	compression tests	1444:1460	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	31	with	microscopy	1306:1315	arg1	Fourier					1358:1364	Fourier	1358:1364	Fourier transform infrared spectroscopy	1358:1396	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	31	with	microscopy	1306:1315	arg1	spectroscopy					1344:1355	energy-disperse X-ray spectroscopy	1322:1355	energy-disperse X-ray spectroscopy	1322:1355	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	4	32	theme	PLA	785:787	arg1	polymers					802:809	Both the PLA and alginate polymers	776:809	polymers	802:809	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	4	32	theme	PLA	785:787	arg1	approved					821:828	approved	821:828	approved	821:828	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	0	33	theme	Bioactive	38:46	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	8	34	theme	tissue	1655:1660	arg1	regeneration					1662:1673	bone tissue regeneration	1650:1673	bone tissue regeneration	1650:1673	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	1	35	theme	antibacterial	396:408	arg1	functions					410:418	antibacterial functions	396:418	antibacterial functions	396:418	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	2	36	theme	bone	489:492	arg1	regeneration					494:505	bone regeneration	489:505	bone regeneration	489:505	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	7	37	from	temperature	1496:1506	arg1	microscopy					1306:1315	field emission scanning electron microscopy	1273:1315	field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature	1273:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	37	from	temperature	1496:1506	arg1	states					1481:1486	dry and swollen states	1465:1486	dry and swollen states at body temperature	1465:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	1	38	theme	reproducible	221:232	arg1	scaffolds					276:284	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	0	39	theme	Alginate	64:71	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	3	40	used	used	664:667	arg2	cations					651:657	Zn2+ cations	646:657	Zn2+ cations	646:657	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	2	41	theme	scaffolds	549:557	arg1	development					530:540	the development	526:540	the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations	526:643	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	1	42	theme	functions	410:418	arg1	lack					358:361	their lack	352:361	their lack of osteoinductive properties and antibacterial functions	352:418	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	8	43	theme	superior	1515:1522	arg1	properties					1536:1545	Their superior compressive properties	1509:1545	Their superior compressive properties	1509:1545	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	7	44	theme	porosity	1417:1424	arg1	measurements					1426:1437	porosity measurements	1417:1437	porosity measurements	1417:1437	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	1	45	theme	three-dimensional	234:250	arg1	acid					264:267	lactic acid	257:267	lactic acid	257:267	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	45	theme	three-dimensional	234:250	arg1	PLA					271:273	PLA	271:273	PLA	271:273	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	45	theme	three-dimensional	234:250	arg1	poly					252:255	three-dimensional poly	234:255	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	0	46	theme	Acid	59:62	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	1	47	theme	tissue	306:311	arg1	applications					325:336	tissue engineering applications	306:336	tissue engineering applications	306:336	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	2	48	theme	PLA	545:547	arg1	scaffolds					549:557	PLA scaffolds	545:557	PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations	545:643	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	8	49	theme	antibacterial	1585:1597	arg1	activities					1599:1608	osteoinductive and antibacterial activities	1566:1608	osteoinductive and antibacterial activities	1566:1608	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	2	50	theme	FDM	452:454	arg1	constructs					456:465	the FDM constructs	448:465	the FDM constructs capable of supporting bone regeneration	448:505	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	1	51	theme	poly	252:255	arg1	scaffolds					276:284	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	52	theme	engineering	313:323	arg1	applications					325:336	tissue engineering applications	306:336	tissue engineering applications	306:336	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	7	53	from	microscopy	1306:1315	arg1	states					1481:1486	dry and swollen states	1465:1486	dry and swollen states at body temperature	1465:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	53	from	microscopy	1306:1315	arg1	temperature					1496:1506	body temperature	1491:1506	body temperature	1491:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	54	theme	water	1399:1403	arg1	absorption					1405:1414	water absorption	1399:1414	water absorption	1399:1414	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	0	55	theme	Composite	73:81	arg1	Scaffolds					83:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds	12:91	Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity.					
36413629	7	56	theme	compression	1444:1454	arg1	tests					1456:1460	compression tests	1444:1460	compression tests	1444:1460	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	7	57	theme	body	1491:1494	arg1	temperature					1496:1506	body temperature	1491:1506	body temperature	1491:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	1	58	theme	fused	158:162	arg1	FDM					185:187	FDM	185:187	FDM	185:187	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	58	theme	fused	158:162	arg1	modeling					175:182	fused deposition modeling	158:182	fused deposition modeling (FDM)	158:188	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	8	59	theme	water	1548:1552	arg1	uptake					1554:1559	water uptake	1548:1559	water uptake	1548:1559	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36413629	3	60	theme	osteoinductive	697:710	arg1	properties					712:721	antibacterial and osteoinductive properties	679:721	antibacterial and osteoinductive properties	679:721	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	5	61	dep	In	870:871	arg1	vivo					873:876	vivo	873:876	vivo	873:876	In vivo bone regeneration capacity was demonstrated on a rabbit model by tomography and histological analysis.					
36413629	1	62	theme	deposition	164:173	arg1	FDM					185:187	FDM	185:187	FDM	185:187	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	62	theme	deposition	164:173	arg1	modeling					175:182	fused deposition modeling	158:182	fused deposition modeling (FDM)	158:188	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	7	63	dep	transform	1366:1374	arg1	infrared					1376:1383	infrared	1376:1383	transform infrared spectroscopy	1366:1396	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	2	64	theme	sodium	572:577	arg1	alginate					579:586	sodium alginate	572:586	sodium alginate cross-linked with both calcium and zinc divalent cations	572:643	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	3	65	theme	Zn2+	646:649	arg1	cations					651:657	Zn2+ cations	646:657	Zn2+ cations	646:657	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	1	66	theme	lactic	257:262	arg1	acid					264:267	lactic acid	257:267	lactic acid	257:267	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	1	66	theme	lactic	257:262	arg1	poly					252:255	three-dimensional poly	234:255	reproducible three-dimensional poly(lactic acid) (PLA) scaffolds	221:284	Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions.					
36413629	7	67	theme	X-ray	1338:1342	arg1	spectroscopy					1344:1355	energy-disperse X-ray spectroscopy	1322:1355	energy-disperse X-ray spectroscopy	1322:1355	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	3	68	theme	antibacterial	679:691	arg1	properties					712:721	antibacterial and osteoinductive properties	679:721	antibacterial and osteoinductive properties	679:721	Zn2+ cations were used to confer antibacterial and osteoinductive properties to enhance the performance of nontoxic PLA-alginate.					
36413629	7	69	theme	dry	1465:1467	arg1	states					1481:1486	dry and swollen states	1465:1486	dry and swollen states at body temperature	1465:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	6	70	theme	microbial	1194:1202	arg1	species					1204:1210	the two microbial species	1186:1210	the two microbial species tested	1186:1217	The scaffolds exhibited antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa, while the control scaffolds could not resist the two microbial species tested.					
36413629	4	71	dep	Food	840:843	arg1	Administration					854:867	Administration	854:867	Administration	854:867	Both the PLA and alginate polymers have been approved by the US Food and Drug Administration.					
36413629	7	72	theme	electron	1297:1304	arg1	microscopy					1306:1315	field emission scanning electron microscopy	1273:1315	field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature	1273:1506	The scaffolds' physical properties were evaluated by field emission scanning electron microscopy with energy-disperse X-ray spectroscopy, Fourier transform infrared spectroscopy, water absorption, porosity measurements, and compression tests in dry and swollen states at body temperature.					
36413629	6	73	dep	Gram-positive	1036:1048	arg1	aeruginosa					1129:1138	Pseudomonas aeruginosa	1117:1138	Pseudomonas aeruginosa	1117:1138	The scaffolds exhibited antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa, while the control scaffolds could not resist the two microbial species tested.					
36413629	6	73	dep	Gram-positive	1036:1048	arg1	epidermidis					1087:1097	methicillin-resistant Staphylococcus epidermidis	1050:1097	methicillin-resistant Staphylococcus epidermidis	1050:1097	The scaffolds exhibited antibacterial activity against Gram-positive methicillin-resistant Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa, while the control scaffolds could not resist the two microbial species tested.					
36413629	2	74	theme	capable	467:473	arg1	constructs					456:465	the FDM constructs	448:465	the FDM constructs capable of supporting bone regeneration	448:505	Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations.					
36413629	8	75	theme	compressive	1524:1534	arg1	properties					1536:1545	Their superior compressive properties	1509:1545	Their superior compressive properties	1509:1545	Their superior compressive properties, water uptake, and osteoinductive and antibacterial activities thus make them promising candidates for bone tissue regeneration.					
36603717	0	0	theme	cellulose	78:86	arg1	skeleton					88:95	wood cellulose skeleton	73:95	wood cellulose skeleton	73:95	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	1	1	theme	films	169:173	arg1	development					127:137	The development	123:137	The development of high-performance composite films using biomass materials	123:197	The development of high-performance composite films using biomass materials have become a sought-after direction.					
36603717	0	2	theme	wood	73:76	arg1	skeleton					88:95	wood cellulose skeleton	73:95	wood cellulose skeleton	73:95	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	6	3	theme	UV-light	838:845	arg1	UV-light					838:845	UV-light	838:845	UV-light	838:845	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
36603717	6	3	theme	UV-light	838:845	arg1	%					833:833	98 %	830:833	98 % of UV-light	830:845	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
36603717	2	4	theme	UV-shielding	294:305	arg1	film					328:331	strong, flexible and UV-shielding biological composite film	273:331	strong, flexible and UV-shielding biological composite film	273:331	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	3	5	theme	Enzymatic	521:529	arg1	lignin					531:536	Enzymatic lignin	521:536	Enzymatic lignin	521:536	In the work, WCS and LNPs were prepared by chemical treatment of wood veneer and Enzymatic lignin, respectively.					
36603717	6	6	theme	thermal	896:902	arg1	stabilities					904:914	the thermal stabilities	892:914	the thermal stabilities	892:914	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
36603717	5	7	theme	composite	689:697	arg1	films					699:703	the composite films	685:703	the composite films	685:703	WCS enhanced the mechanical properties of the composite films, the tensile stress reached to 85.8 MPa and the tensile strain reached to 6.39 %.					
36603717	3	8	theme	veneer	510:515	arg1	treatment					492:500	chemical treatment	483:500	chemical treatment of wood veneer and Enzymatic lignin, respectively	483:550	In the work, WCS and LNPs were prepared by chemical treatment of wood veneer and Enzymatic lignin, respectively.					
36603717	5	9	theme	films	699:703	arg1	properties					671:680	the mechanical properties	656:680	the mechanical properties of the composite films	656:703	WCS enhanced the mechanical properties of the composite films, the tensile stress reached to 85.8 MPa and the tensile strain reached to 6.39 %.					
36603717	7	10	theme	composite	1019:1027	arg1	films					1029:1033	high quality biological composite films	995:1033	high quality biological composite films	995:1033	These findings would provide some references for exploring high quality biological composite films.					
36603717	0	11	with	films	62:66	arg1	skeleton					88:95	wood cellulose skeleton	73:95	wood cellulose skeleton	73:95	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	0	11	with	films	62:66	arg1	nanoparticles					108:120	lignin nanoparticles	101:120	lignin nanoparticles	101:120	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	2	12	theme	flexible	281:288	arg1	film					328:331	strong, flexible and UV-shielding biological composite film	273:331	strong, flexible and UV-shielding biological composite film	273:331	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	1	13	theme	biomass	181:187	arg1	materials					189:197	biomass materials	181:197	biomass materials	181:197	The development of high-performance composite films using biomass materials have become a sought-after direction.					
36603717	0	14	theme	lignin	101:106	arg1	nanoparticles					108:120	lignin nanoparticles	101:120	lignin nanoparticles	101:120	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	7	15	theme	high	995:998	arg1	films					1029:1033	high quality biological composite films	995:1033	high quality biological composite films	995:1033	These findings would provide some references for exploring high quality biological composite films.					
36603717	2	16	dep	method	253:258	arg1	fabricate					263:271	fabricate	263:271	to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA)	260:423	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	5	17	theme	tensile	753:759	arg1	strain					761:766	the tensile strain	749:766	the tensile strain	749:766	WCS enhanced the mechanical properties of the composite films, the tensile stress reached to 85.8 MPa and the tensile strain reached to 6.39 %.					
36603717	3	18	theme	chemical	483:490	arg1	treatment					492:500	chemical treatment	483:500	chemical treatment of wood veneer and Enzymatic lignin, respectively	483:550	In the work, WCS and LNPs were prepared by chemical treatment of wood veneer and Enzymatic lignin, respectively.					
36603717	7	19	theme	quality	1000:1006	arg1	films					1029:1033	high quality biological composite films	995:1033	high quality biological composite films	995:1033	These findings would provide some references for exploring high quality biological composite films.					
36603717	3	20	theme	lignin	531:536	arg1	treatment					492:500	chemical treatment	483:500	chemical treatment of wood veneer and Enzymatic lignin, respectively	483:550	In the work, WCS and LNPs were prepared by chemical treatment of wood veneer and Enzymatic lignin, respectively.					
36603717	4	21	theme	composite	626:634	arg1	films					636:640	composite films	626:640	composite films	626:640	Then, WCS was infiltrated with the LNPs/PVA mixtures and dried to obtain composite films.					
36603717	0	22	theme	Strong	0:5	arg1	alcohol					54:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	7	23	theme	biological	1008:1017	arg1	films					1029:1033	high quality biological composite films	995:1033	high quality biological composite films	995:1033	These findings would provide some references for exploring high quality biological composite films.					
36603717	2	24	theme	composite	318:326	arg1	film					328:331	strong, flexible and UV-shielding biological composite film	273:331	strong, flexible and UV-shielding biological composite film	273:331	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	4	25	theme	LNPs/PVA	588:595	arg1	mixtures					597:604	the LNPs/PVA mixtures	584:604	the LNPs/PVA mixtures	584:604	Then, WCS was infiltrated with the LNPs/PVA mixtures and dried to obtain composite films.					
36603717	0	26	theme	flexible	8:15	arg1	alcohol					54:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	5	27	theme	mechanical	660:669	arg1	properties					671:680	the mechanical properties	656:680	the mechanical properties of the composite films	656:703	WCS enhanced the mechanical properties of the composite films, the tensile stress reached to 85.8 MPa and the tensile strain reached to 6.39 %.					
36603717	2	28	theme	biological	307:316	arg1	film					328:331	strong, flexible and UV-shielding biological composite film	273:331	strong, flexible and UV-shielding biological composite film	273:331	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	1	29	theme	sought-after	213:224	arg1	direction					226:234	a sought-after direction	211:234	a sought-after direction	211:234	The development of high-performance composite films using biomass materials have become a sought-after direction.					
36603717	0	30	theme	composite	34:42	arg1	alcohol					54:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	2	31	theme	green	247:251	arg1	method					253:258	a green method	245:258	a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA)	245:423	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	32	theme	polyvinyl	401:409	arg1	PVA					420:422	PVA	420:422	PVA	420:422	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	32	theme	polyvinyl	401:409	arg1	alcohol					411:417	polyvinyl alcohol	401:417	polyvinyl alcohol (PVA)	401:423	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	0	33	theme	UV-shielding	21:32	arg1	alcohol					54:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	6	34	theme	composite	791:799	arg1	films					801:805	The composite films	787:805	The composite films with LNPs	787:815	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
36603717	0	35	theme	polyvinyl	44:52	arg1	alcohol					54:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol	0:60	Strong, flexible and UV-shielding composite polyvinyl alcohol films with wood cellulose skeleton and lignin nanoparticles.					
36603717	6	36	theme	water	852:856	arg1	absorption					858:867	the water absorption	848:867	the water absorption	848:867	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
36603717	1	37	theme	high-performance	142:157	arg1	films					169:173	high-performance composite films	142:173	high-performance composite films using biomass materials	142:197	The development of high-performance composite films using biomass materials have become a sought-after direction.					
36603717	2	38	theme	strong	273:278	arg1	film					328:331	strong, flexible and UV-shielding biological composite film	273:331	strong, flexible and UV-shielding biological composite film	273:331	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	39	theme	cellulose	343:351	arg1	skeleton					353:360	wood cellulose skeleton	338:360	wood cellulose skeleton (WCS)	338:366	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	39	theme	cellulose	343:351	arg1	WCS					363:365	WCS	363:365	WCS	363:365	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	3	40	theme	wood	505:508	arg1	veneer					510:515	wood veneer	505:515	wood veneer	505:515	In the work, WCS and LNPs were prepared by chemical treatment of wood veneer and Enzymatic lignin, respectively.					
36603717	2	41	theme	wood	338:341	arg1	skeleton					353:360	wood cellulose skeleton	338:360	wood cellulose skeleton (WCS)	338:366	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	41	theme	wood	338:341	arg1	WCS					363:365	WCS	363:365	WCS	363:365	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	42	theme	lignin	369:374	arg1	LNPs					391:394	LNPs	391:394	LNPs	391:394	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	2	42	theme	lignin	369:374	arg1	nanoparticles					376:388	lignin nanoparticles	369:388	lignin nanoparticles (LNPs)	369:395	Herein, a green method to fabricate strong, flexible and UV-shielding biological composite film from wood cellulose skeleton (WCS), lignin nanoparticles (LNPs) and polyvinyl alcohol (PVA) was described.					
36603717	5	43	theme	tensile	710:716	arg1	stress					718:723	the tensile stress	706:723	the tensile stress	706:723	WCS enhanced the mechanical properties of the composite films, the tensile stress reached to 85.8 MPa and the tensile strain reached to 6.39 %.					
36603717	1	44	theme	composite	159:167	arg1	films					169:173	high-performance composite films	142:173	high-performance composite films using biomass materials	142:197	The development of high-performance composite films using biomass materials have become a sought-after direction.					
36603717	6	45	with	films	801:805	arg1	LNPs					812:815	LNPs	812:815	LNPs	812:815	The composite films with LNPs blocked over 98 % of UV-light, the water absorption decreased by 30 %, and the thermal stabilities were also improved.					
37307459	9	0	theme	communities	1362:1372	arg1	composition					1326:1336	the composition	1322:1336	the composition of intestinal microbial communities	1322:1372	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	6	1	theme	Bt	904:905	arg1	biofilms					907:914	Bt biofilms	904:914	Bt biofilms	904:914	By combining simulations with experiments, we demonstrate that in flow, Bt biofilms share dextran metabolic by-products, promoting Bf biofilm formation.					
37307459	3	2	dep	organization	380:391	arg1	the					368:370	the	368:370	the	368:370	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	8	3	theme	good	1229:1232	arg1	concentration					1234:1246	the effective public good concentration	1208:1246	the effective public good concentration	1208:1246	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	8	4	theme	strong	1154:1159	arg1	flows					1161:1165	sufficiently strong flows	1141:1165	sufficiently strong flows	1141:1165	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	4	5	theme	representative	618:631	arg1	commensals					639:648	two representative human commensals	614:648	two representative human commensals	614:648	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	5	theme	representative	618:631	arg1	Bt					579:580	Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis	549:606	Bt	579:580	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	3	6	theme	fluid	349:353	arg1	flow					355:358	fluid flow	349:358	fluid flow	349:358	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	8	7	theme	effective	1212:1220	arg1	concentration					1234:1246	the effective public good concentration	1208:1246	the effective public good concentration	1208:1246	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	0	8	theme	biofilm	37:43	arg1	communities					45:55	gut microbiota biofilm communities	22:55	gut microbiota biofilm communities	22:55	Fluid flow structures gut microbiota biofilm communities by distributing public goods.					
37307459	8	9	theme	Bf	1175:1176	arg1	formation					1186:1194	Bf biofilm formation	1175:1194	Bf biofilm formation	1175:1194	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	3	10	theme	different	451:459	arg1	species					461:467	different species	451:467	different species	451:467	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	8	11	theme	biofilm	1178:1184	arg1	formation					1186:1194	Bf biofilm formation	1175:1194	Bf biofilm formation	1175:1194	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	1	12	theme	Bacterial	87:95	arg1	commensals					101:110	Bacterial gut commensals	87:110	Bacterial gut commensals	87:110	Bacterial gut commensals experience a biologically and physically complex mucosal environment.					
37307459	0	13	theme	Fluid	0:4	arg1	flow					6:9	Fluid flow	0:9	Fluid flow	0:9	Fluid flow structures gut microbiota biofilm communities by distributing public goods.					
37307459	6	14	theme	biofilm	966:972	arg1	formation					974:982	Bf biofilm formation	963:982	Bf biofilm formation	963:982	By combining simulations with experiments, we demonstrate that in flow, Bt biofilms share dextran metabolic by-products, promoting Bf biofilm formation.					
37307459	1	15	theme	gut	97:99	arg1	commensals					101:110	Bacterial gut commensals	87:110	Bacterial gut commensals	87:110	Bacterial gut commensals experience a biologically and physically complex mucosal environment.					
37307459	3	16	theme	spatial	372:378	arg1	organization					380:391	spatial organization	372:391	spatial organization	372:391	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	6	17	theme	Bf	963:964	arg1	formation					974:982	Bf biofilm formation	963:982	Bf biofilm formation	963:982	By combining simulations with experiments, we demonstrate that in flow, Bt biofilms share dextran metabolic by-products, promoting Bf biofilm formation.					
37307459	2	18	theme	mechanics	312:320	arg1	role					304:307	the role	300:307	the role of mechanics	300:320	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	5	19	theme	Bf	821:822	arg1	growth					824:829	Bf growth	821:829	Bf growth	821:829	We identified dextran as a polysaccharide readily metabolized by Bt but not Bf, but whose fermentation generates a public good enabling Bf growth.					
37307459	4	20	theme	Bacteroides	587:597	arg1	fragilis					599:606	Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis	549:606	fragilis	599:606	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	7	21	theme	community	1067:1075	arg1	organization					1047:1058	the spatial organization	1035:1058	the spatial organization of the community	1035:1075	By transporting this public good, flow structures the spatial organization of the community, positioning the Bf population downstream from Bt.					
37307459	3	22	theme	biofilm	416:422	arg1	communities					424:434	gut biofilm communities	412:434	gut biofilm communities	412:434	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	9	23	theme	microbial	1352:1360	arg1	communities					1362:1372	intestinal microbial communities	1341:1372	intestinal microbial communities	1341:1372	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	2	24	theme	chemical	193:200	arg1	factors					202:208	many chemical factors	188:208	many chemical factors	188:208	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	2	25	theme	microbial	257:265	arg1	communities					267:277	these microbial communities	251:277	these microbial communities	251:277	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	9	26	theme	intestinal	1341:1350	arg1	communities					1362:1372	intestinal microbial communities	1341:1372	intestinal microbial communities	1341:1372	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	0	27	theme	microbiota	26:35	arg1	communities					45:55	gut microbiota biofilm communities	22:55	gut microbiota biofilm communities	22:55	Fluid flow structures gut microbiota biofilm communities by distributing public goods.					
37307459	4	28	theme	Bacteroides	549:559	arg1	Bf					609:610	Bf	609:610	Bf	609:610	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	28	theme	Bacteroides	549:559	arg1	commensals					639:648	two representative human commensals	614:648	two representative human commensals	614:648	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	28	theme	Bacteroides	549:559	arg1	Bt					579:580	Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis	549:606	Bt	579:580	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	3	29	theme	communities	424:434	arg1	composition					397:407	composition	397:407	composition	397:407	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	3	29	theme	communities	424:434	arg1	organization					380:391	spatial organization	372:391	spatial organization	372:391	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	2	30	theme	many	188:191	arg1	factors					202:208	many chemical factors	188:208	many chemical factors	188:208	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	0	31	theme	gut	22:24	arg1	communities					45:55	gut microbiota biofilm communities	22:55	gut microbiota biofilm communities	22:55	Fluid flow structures gut microbiota biofilm communities by distributing public goods.					
37307459	8	32	theme	public	1222:1227	arg1	concentration					1234:1246	the effective public good concentration	1208:1246	the effective public good concentration	1208:1246	We show that sufficiently strong flows abolish Bf biofilm formation by limiting the effective public good concentration at the surface.					
37307459	6	33	theme	metabolic	930:938	arg1	by-products					940:950	dextran metabolic by-products	922:950	dextran metabolic by-products	922:950	By combining simulations with experiments, we demonstrate that in flow, Bt biofilms share dextran metabolic by-products, promoting Bf biofilm formation.					
37307459	3	34	theme	gut	412:414	arg1	communities					424:434	gut biofilm communities	412:434	gut biofilm communities	412:434	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	6	35	theme	dextran	922:928	arg1	by-products					940:950	dextran metabolic by-products	922:950	dextran metabolic by-products	922:950	By combining simulations with experiments, we demonstrate that in flow, Bt biofilms share dextran metabolic by-products, promoting Bf biofilm formation.					
37307459	7	36	theme	spatial	1039:1045	arg1	organization					1047:1058	the spatial organization	1035:1058	the spatial organization of the community	1035:1075	By transporting this public good, flow structures the spatial organization of the community, positioning the Bf population downstream from Bt.					
37307459	7	37	theme	Bf	1094:1095	arg1	population					1097:1106	the Bf population	1090:1106	the Bf population	1090:1106	By transporting this public good, flow structures the spatial organization of the community, positioning the Bf population downstream from Bt.					
37307459	4	38	theme	thetaiotaomicron	561:576	arg1	Bf					609:610	Bf	609:610	Bf	609:610	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	38	theme	thetaiotaomicron	561:576	arg1	commensals					639:648	two representative human commensals	614:648	two representative human commensals	614:648	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	38	theme	thetaiotaomicron	561:576	arg1	Bt					579:580	Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis	549:606	Bt	579:580	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	3	39	dep	impacts	360:366	arg1	interact					469:476	interact	469:476	interact metabolically	469:490	Here, we demonstrate that fluid flow impacts the spatial organization and composition of gut biofilm communities by shaping how different species interact metabolically.					
37307459	9	40	theme	host	1397:1400	arg1	health					1402:1407	host health	1397:1407	host health	1397:1407	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	9	41	theme	Physical	1264:1271	arg1	flow					1289:1292	flow	1289:1292	flow	1289:1292	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	9	41	theme	Physical	1264:1271	arg1	factors					1273:1279	Physical factors	1264:1279	Physical factors such as flow	1264:1292	Physical factors such as flow may therefore contribute to the composition of intestinal microbial communities, potentially impacting host health.					
37307459	0	42	theme	public	73:78	arg1	goods					80:84	public goods	73:84	public goods	73:84	Fluid flow structures gut microbiota biofilm communities by distributing public goods.					
37307459	1	43	theme	complex	153:159	arg1	environment					169:179	a biologically and physically complex mucosal environment	123:179	a biologically and physically complex mucosal environment	123:179	Bacterial gut commensals experience a biologically and physically complex mucosal environment.					
37307459	4	44	theme	robust	660:665	arg1	biofilms					667:674	robust biofilms	660:674	robust biofilms	660:674	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	45	theme	human	633:637	arg1	commensals					639:648	two representative human commensals	614:648	two representative human commensals	614:648	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	45	theme	human	633:637	arg1	Bt					579:580	Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis	549:606	Bt	579:580	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	4	46	theme	model	521:525	arg1	community					527:535	a model community	519:535	a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals,	519:649	We first demonstrate that a model community composed of Bacteroides thetaiotaomicron (Bt) and Bacteroides fragilis (Bf), two representative human commensals, can form robust biofilms in flow.					
37307459	2	47	theme	communities	267:277	arg1	structure					238:246	structure	238:246	structure	238:246	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	2	47	theme	communities	267:277	arg1	composition					222:232	composition	222:232	composition	222:232	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
37307459	1	48	theme	mucosal	161:167	arg1	environment					169:179	a biologically and physically complex mucosal environment	123:179	a biologically and physically complex mucosal environment	123:179	Bacterial gut commensals experience a biologically and physically complex mucosal environment.					
37307459	2	49	dep	composition	222:232	arg1	the					218:220	the	218:220	the	218:220	While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics.					
36372497	4	0	theme	surface	1017:1023	arg1	appearance					1025:1034	surface appearance	1017:1034	surface appearance	1017:1034	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	5	1	theme	packaging	1173:1181	arg1	material					1183:1190	a prospective eco-friendly packaging material	1146:1190	a prospective eco-friendly packaging material for fruit preservation	1146:1213	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	4	2	theme	composite	891:899	arg1	film					901:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	3	3	theme	water	507:511	arg1	permeability					519:530	water vapor permeability	507:530	water vapor permeability	507:530	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	4	theme	dosage	835:840	arg1	increase					795:802	the increase	791:802	the increase of mustard essential oil (MEO) dosage	791:840	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	4	5	theme	mango	945:949	arg1	fruits					951:956	mango fruits	945:956	mango fruits	945:956	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	4	6	theme	MEO	887:889	arg1	film					901:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	1	7	theme	modified	176:183	arg1	gum					192:194	modified gellan gum	176:194	modified gellan gum	176:194	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	4	8	theme	storage	976:982	arg1	20 days					965:971	20 days	965:971	20 days of storage based on the characterization of surface appearance and quality indexes of fruits	965:1064	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	3	9	theme	films	584:588	arg1	permeability					519:530	water vapor permeability	507:530	water vapor permeability	507:530	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	9	theme	films	584:588	arg1	permeability					543:554	oxygen permeability	536:554	oxygen permeability	536:554	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	10	theme	MEO	830:832	arg1	dosage					835:840	mustard essential oil (MEO) dosage	807:840	mustard essential oil (MEO) dosage	807:840	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	0	11	theme	mango	102:106	arg1	preservation					108:119	mango preservation	102:119	mango preservation	102:119	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	3	12	theme	CMCS-g-CA/CMGG	559:572	arg1	films					584:588	CMCS-g-CA/CMGG composite films	559:588	CMCS-g-CA/CMGG composite films incorporated with mustard essential oil	559:628	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	2	13	dep	infrared	380:387	arg1	FT-IR					390:394	FT-IR	390:394	FT-IR	390:394	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	4	14	theme	appearance	1025:1034	arg1	characterization					997:1012	the characterization	993:1012	the characterization of surface appearance and quality indexes of fruits	993:1064	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	2	15	theme	CMCS-g-CA/CMGG	293:306	arg1	5:2					326:328	5:2	326:328	5:2	326:328	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	15	theme	CMCS-g-CA/CMGG	293:306	arg1	ratio					284:288	The optimal weight ratio	265:288	The optimal weight ratio of CMCS-g-CA/CMGG	265:306	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	1	16	theme	gellan	185:190	arg1	gum					192:194	modified gellan gum	176:194	modified gellan gum	176:194	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	4	17	theme	fruits	1059:1064	arg1	appearance					1025:1034	surface appearance	1017:1034	surface appearance	1017:1034	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	4	17	theme	fruits	1059:1064	arg1	indexes					1048:1054	quality indexes	1040:1054	quality indexes of fruits	1040:1064	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	0	18	theme	chitosan/carboxymethyl	12:33	arg1	films					56:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	5	19	theme	prospective	1148:1158	arg1	material					1183:1190	a prospective eco-friendly packaging material	1146:1190	a prospective eco-friendly packaging material for fruit preservation	1146:1213	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	4	20	theme	CMCS-g-CA/CMGG + 2.0 μL/mL	860:885	arg1	film					901:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film	856:904	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	2	21	theme	Thermogravimetric	398:414	arg1	analysis					416:423	Thermogravimetric analysis	398:423	Thermogravimetric analysis (TGA)	398:429	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	21	theme	Thermogravimetric	398:414	arg1	properties					455:464	mechanical and barrier properties	432:464	properties	455:464	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	21	theme	Thermogravimetric	398:414	arg1	TGA					426:428	TGA	426:428	TGA	426:428	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	0	22	theme	Amphiphilic	0:10	arg1	films					56:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	5	23	theme	CMCA-g-CA/CMGG/MEO	1094:1111	arg1	films					1123:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	0	24	theme	gum	42:44	arg1	films					56:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	4	25	from	preservation	929:940	arg1	fruits					951:956	mango fruits	945:956	mango fruits	945:956	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	1	26	dep	chitosan	149:156	arg1	gum					192:194	modified gellan gum	176:194	modified gellan gum	176:194	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	2	27	theme	mechanical	432:441	arg1	properties					455:464	mechanical and barrier properties	432:464	properties	455:464	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	27	theme	mechanical	432:441	arg1	analysis					416:423	Thermogravimetric analysis	398:423	Thermogravimetric analysis (TGA)	398:429	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	0	28	theme	gellan	35:40	arg1	films					56:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	3	29	theme	oxygen	536:541	arg1	permeability					543:554	oxygen permeability	536:554	oxygen permeability	536:554	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	5	30	theme	composite	1113:1121	arg1	films					1123:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	2	31	dep	Fourier	362:368	arg1	transform					370:378	transform	370:378	transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films	370:487	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	32	theme	films	483:487	arg1	properties					455:464	mechanical and barrier properties	432:464	properties	455:464	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	32	theme	films	483:487	arg1	analysis					416:423	Thermogravimetric analysis	398:423	Thermogravimetric analysis (TGA)	398:429	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	5	33	theme	fruit	1196:1200	arg1	preservation					1202:1213	fruit preservation	1196:1213	fruit preservation	1196:1213	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	0	34	theme	composite	46:54	arg1	films					56:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films	0:60	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	2	35	theme	barrier	447:453	arg1	properties					455:464	mechanical and barrier properties	432:464	properties	455:464	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	35	theme	barrier	447:453	arg1	analysis					416:423	Thermogravimetric analysis	398:423	Thermogravimetric analysis (TGA)	398:429	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	1	36	theme	active	227:232	arg1	material					255:262	an active edible fresh-keeping material	224:262	an active edible fresh-keeping material	224:262	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	2	37	theme	composite	473:481	arg1	films					483:487	the composite films	469:487	the composite films	469:487	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	4	38	theme	effective	919:927	arg1	preservation					929:940	an effective preservation	916:940	an effective preservation on mango fruits	916:956	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	3	39	theme	antibacterial	657:669	arg1	property					671:678	the antibacterial property	653:678	the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis	653:760	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	40	theme	mustard	608:614	arg1	oil					626:628	mustard essential oil	608:628	mustard essential oil	608:628	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	4	41	theme	quality	1040:1046	arg1	indexes					1048:1054	quality indexes	1040:1054	quality indexes of fruits	1040:1064	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	3	42	theme	composite	574:582	arg1	films					584:588	CMCS-g-CA/CMGG composite films	559:588	CMCS-g-CA/CMGG composite films incorporated with mustard essential oil	559:628	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	43	theme	film	697:700	arg1	solutions					702:710	the composite film solutions	683:710	the composite film solutions against E. coli, S. aureus and Bacillus anthracis	683:760	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	44	theme	essential	616:624	arg1	oil					626:628	mustard essential oil	608:628	mustard essential oil	608:628	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	45	theme	vapor	513:517	arg1	permeability					519:530	water vapor permeability	507:530	water vapor permeability	507:530	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	2	46	theme	Fourier	362:368	arg1	characterization					342:357	the characterization	338:357	the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films	338:487	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	3	47	theme	solutions	702:710	arg1	property					671:678	the antibacterial property	653:678	the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis	653:760	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	2	48	dep	transform	370:378	arg1	infrared					380:387	infrared	380:387	infrared	380:387	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	1	49	theme	edible	234:239	arg1	material					255:262	an active edible fresh-keeping material	224:262	an active edible fresh-keeping material	224:262	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	5	50	theme	multifunctional	1078:1092	arg1	films					1123:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	the multifunctional CMCA-g-CA/CMGG/MEO composite films	1074:1127	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	2	51	theme	weight	277:282	arg1	5:2					326:328	5:2	326:328	5:2	326:328	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	51	theme	weight	277:282	arg1	ratio					284:288	The optimal weight ratio	265:288	The optimal weight ratio of CMCS-g-CA/CMGG	265:306	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	1	52	theme	fresh-keeping	241:253	arg1	material					255:262	an active edible fresh-keeping material	224:262	an active edible fresh-keeping material	224:262	In this paper, amphiphilic chitosan and carboxymethyl modified gellan gum were synthesized to develop an active edible fresh-keeping material.					
36372497	0	53	theme	essential	84:92	arg1	oil					94:96	mustard essential oil	76:96	mustard essential oil for mango preservation	76:119	Amphiphilic chitosan/carboxymethyl gellan gum composite films enriched with mustard essential oil for mango preservation.					
36372497	3	54	theme	composite	687:695	arg1	solutions					702:710	the composite film solutions	683:710	the composite film solutions against E. coli, S. aureus and Bacillus anthracis	683:760	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	2	55	theme	optimal	269:275	arg1	5:2					326:328	5:2	326:328	5:2	326:328	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	2	55	theme	optimal	269:275	arg1	ratio					284:288	The optimal weight ratio	265:288	The optimal weight ratio of CMCS-g-CA/CMGG	265:306	The optimal weight ratio of CMCS-g-CA/CMGG was determined as 5:2 through the characterization of Fourier transform infrared (FT-IR), Thermogravimetric analysis (TGA), mechanical and barrier properties of the composite films.					
36372497	3	56	theme	mustard	807:813	arg1	dosage					835:840	mustard essential oil (MEO) dosage	807:840	mustard essential oil (MEO) dosage	807:840	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	4	57	theme	indexes	1048:1054	arg1	characterization					997:1012	the characterization	993:1012	the characterization of surface appearance and quality indexes of fruits	993:1064	Furthermore, the CMCS-g-CA/CMGG + 2.0 μL/mL MEO composite film exhibited an effective preservation on mango fruits during 20 days of storage based on the characterization of surface appearance and quality indexes of fruits.					
36372497	5	58	theme	eco-friendly	1160:1171	arg1	material					1183:1190	a prospective eco-friendly packaging material	1146:1190	a prospective eco-friendly packaging material for fruit preservation	1146:1213	Hence, the multifunctional CMCA-g-CA/CMGG/MEO composite films can be served as a prospective eco-friendly packaging material for fruit preservation.					
36372497	3	59	dep	permeability	519:530	arg1	the					503:505	the	503:505	the	503:505	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	60	theme	oil	825:827	arg1	dosage					835:840	mustard essential oil (MEO) dosage	807:840	mustard essential oil (MEO) dosage	807:840	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36372497	3	61	theme	essential	815:823	arg1	dosage					835:840	mustard essential oil (MEO) dosage	807:840	mustard essential oil (MEO) dosage	807:840	In addition, the water vapor permeability and oxygen permeability of CMCS-g-CA/CMGG composite films incorporated with mustard essential oil were all declined, and the antibacterial property of the composite film solutions against E. coli, S. aureus and Bacillus anthracis was distinctly improved with the increase of mustard essential oil (MEO) dosage.					
36423835	3	0	theme	biomass	458:464	arg1	materials					470:478	three typical biomass raw materials	444:478	three typical biomass raw materials	444:478	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	7	1	theme	ignition	1304:1311	arg1	temperature					1313:1323	ignition temperature	1304:1323	ignition temperature	1304:1323	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	4	2	theme	±	773:773	arg1	mg/kg					780:784	48.9 ± 65.2 mg/kg	768:784	48.9 ± 65.2 mg/kg	768:784	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	2	theme	±	773:773	arg1	hemicellulose					753:765	hemicellulose	753:765	hemicellulose (48.9 ± 65.2 mg/kg)	753:785	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	8	3	theme	indene-involved	1707:1721	arg1	RSR-pathway					1723:1733	the indene-involved RSR-pathway	1703:1733	the indene-involved RSR-pathway	1703:1733	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	8	3	theme	indene-involved	1707:1721	arg1	related					1747:1753	related	1747:1753	related	1747:1753	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	3	4	theme	laboratory	494:503	arg1	experiments					516:526	laboratory combustion experiments	494:526	laboratory combustion experiments	494:526	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	1	5	theme	elemental	242:250	arg1	EC					260:261	EC	260:261	EC	260:261	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	5	theme	elemental	242:250	arg1	carbon					252:257	elemental carbon	242:257	elemental carbon (EC)	242:262	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	4	6	theme	0.450	940:944	arg1	hemicellulose					925:937	hemicellulose	925:937	hemicellulose (0.450 ± 0.480 g/kg)	925:958	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	6	theme	0.450	940:944	arg1	g/kg					954:957	0.450 ± 0.480 g/kg	940:957	0.450 ± 0.480 g/kg	940:957	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	3	7	used	used	485:488	arg2	three-components					412:427	the three-components	408:427	the three-components extracted from three typical biomass raw materials	408:478	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	0	8	theme	Emission	0:7	arg1	characteristics					9:23	Emission characteristics	0:23	Emission characteristics	0:23	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	8	9	theme	correlation	1549:1559	arg1	analysis					1561:1568	correlation analysis	1549:1568	correlation analysis combined with cluster analysis	1549:1599	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	1	10	theme	Biomass	156:162	arg1	burning					164:170	Biomass burning	156:170	Biomass burning	156:170	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	10	theme	Biomass	156:162	arg1	source					188:193	an important source	175:193	an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC)	175:262	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	10	11	theme	medium-molecular-weight	2138:2160	arg1	PAHs					2162:2165	medium-molecular-weight PAHs	2138:2165	medium-molecular-weight PAHs	2138:2165	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	1	12	theme	carbon	252:257	arg1	burning					164:170	Biomass burning	156:170	Biomass burning	156:170	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	12	theme	carbon	252:257	arg1	source					188:193	an important source	175:193	an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC)	175:262	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	9	13	theme	raw	2008:2010	arg1	materials					2012:2020	raw materials	2008:2020	raw materials	2008:2020	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	8	14	theme	cluster	1584:1590	arg1	analysis					1592:1599	cluster analysis	1584:1599	cluster analysis	1584:1599	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	1	15	theme	important	178:186	arg1	burning					164:170	Biomass burning	156:170	Biomass burning	156:170	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	15	theme	important	178:186	arg1	source					188:193	an important source	175:193	an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC)	175:262	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	7	16	theme	EC	1447:1448	arg1	formations					1450:1459	EC formations	1447:1459	EC formations	1447:1459	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	4	17	theme	emission	804:811	arg1	factors					813:819	the average emission factors	792:819	the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	792:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	18	theme	hemicellulose	925:937	arg1	order					855:859	the descending order	840:859	the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	840:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	6	19	theme	EC	1263:1264	arg1	characteristics					1235:1249	the emission characteristics	1222:1249	the emission characteristics of PAHs and EC	1222:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	10	20	theme	different	2105:2113	arg1	pathways					2125:2132	the different formation pathways	2101:2132	the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC	2101:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	4	21	theme	emission	638:645	arg1	factors					647:653	The average emission factors	626:653	The average emission factors of the 16 kinds of PAHs	626:677	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	5	22	theme	higher	1122:1127	arg1	proportion					1129:1138	significantly higher proportion	1108:1138	significantly higher proportion	1108:1138	The proportion of naphthalene emitted from cellulose and hemicellulose combustion is higher, while fluoranthene and pyrene accounted significantly higher proportion for lignin.					
36423835	0	23	theme	EC	64:65	arg1	characteristics					9:23	Emission characteristics	0:23	Emission characteristics	0:23	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	0	23	theme	EC	64:65	arg1	mechanisms					41:50	influencing mechanisms	29:50	influencing mechanisms	29:50	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	3	24	theme	emission	567:574	arg1	factors					576:582	emission factors	567:582	emission factors	567:582	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	8	25	theme	different	1642:1650	arg1	effects					1652:1658	different effects	1642:1658	different effects on PAH growth for the three-components	1642:1697	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	6	26	theme	oxygen	1204:1209	arg1	content					1211:1217	oxygen content	1204:1217	oxygen content	1204:1217	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	7	27	theme	oxygen	1388:1393	arg1	content					1395:1401	oxygen content	1388:1401	oxygen content	1388:1401	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	6	28	theme	temperature	1188:1198	arg1	influence					1166:1174	the influence	1162:1174	the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC	1162:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	0	29	dep	components	96:105	arg1	hemicellulose					119:131	hemicellulose	119:131	hemicellulose	119:131	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	0	29	dep	components	96:105	arg1	cellulose					108:116	cellulose	108:116	cellulose	108:116	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	0	29	dep	components	96:105	arg1	lignin					134:139	lignin	134:139	lignin	134:139	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	4	30	theme	kinds	665:669	arg1	factors					647:653	The average emission factors	626:653	The average emission factors of the 16 kinds of PAHs	626:677	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	10	31	theme	further	2244:2250	arg1	studies					2252:2258	further studies	2244:2258	further studies	2244:2258	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	4	32	theme	±	707:707	arg1	mg/kg					713:717	135 ± 180 mg/kg	703:717	135 ± 180 mg/kg	703:717	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	32	theme	±	707:707	arg1	lignin					695:700	lignin	695:700	lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	695:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	0	33	theme	components	96:105	arg1	combustion					76:85	the combustion	72:85	the combustion of three components (cellulose, hemicellulose, lignin) of biomasses	72:153	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	10	34	theme	EC	2311:2312	arg1	mechanisms					2288:2297	the generation mechanisms	2273:2297	the generation mechanisms of PAHs and EC	2273:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	8	35	theme	ring	1839:1842	arg1	PAHs					1844:1847	2-4 ring PAHs	1835:1847	2-4 ring PAHs for hemicellulose	1835:1865	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	8	36	contain	had	1638:1640	arg2	effects					1652:1658	different effects	1642:1658	different effects on PAH growth for the three-components	1642:1697	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	8	36	contain	had	1638:1640	arg1	RSR-pathway					1617:1627	the RSR-pathway	1613:1627	the RSR-pathway	1613:1627	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	7	37	theme	chain	1510:1514	arg1	RSR					1526:1528	RSR	1526:1528	RSR	1526:1528	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	7	37	theme	chain	1510:1514	arg1	reaction					1516:1523	resonance-stabilized hydrocarbon-radical chain reaction	1469:1523	resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway	1469:1537	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	2	38	theme	biomass	384:390	arg1	lignin					343:348	lignin	343:348	lignin	343:348	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	38	theme	biomass	384:390	arg1	Cellulose					313:321	Cellulose	313:321	Cellulose	313:321	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	38	theme	biomass	384:390	arg1	hemicellulose					324:336	hemicellulose	324:336	hemicellulose	324:336	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	38	theme	biomass	384:390	arg1	components					370:379	the three major components	354:379	the three major components of biomass	354:390	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	6	39	from	influence	1166:1174	arg1	characteristics					1235:1249	the emission characteristics	1222:1249	the emission characteristics of PAHs and EC	1222:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	10	40	theme	generation	2277:2286	arg1	mechanisms					2288:2297	the generation mechanisms	2273:2297	the generation mechanisms of PAHs and EC	2273:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	7	41	theme	resonance-stabilized	1469:1488	arg1	RSR					1526:1528	RSR	1526:1528	RSR	1526:1528	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	7	41	theme	resonance-stabilized	1469:1488	arg1	reaction					1516:1523	resonance-stabilized hydrocarbon-radical chain reaction	1469:1523	resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway	1469:1537	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	4	42	theme	cellulose	864:872	arg1	order					855:859	the descending order	840:859	the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	840:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	3	43	theme	PAHs	613:616	arg1	factors					576:582	emission factors	567:582	emission factors	567:582	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	3	43	theme	PAHs	613:616	arg1	compositions					597:608	chemical compositions	588:608	chemical compositions	588:608	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	10	44	theme	PAHs	2302:2305	arg1	mechanisms					2288:2297	the generation mechanisms	2273:2297	the generation mechanisms of PAHs and EC	2273:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	4	45	theme	±	738:738	arg1	mg/kg					744:748	97.8 ± 124 mg/kg	733:748	97.8 ± 124 mg/kg	733:748	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	45	theme	±	738:738	arg1	cellulose					722:730	cellulose	722:730	cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	722:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	6	46	theme	emission	1226:1233	arg1	characteristics					1235:1249	the emission characteristics	1222:1249	the emission characteristics of PAHs and EC	1222:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	9	47	theme	fitted	1891:1896	arg1	results					1898:1904	the fitted results	1887:1904	the fitted results according to the proportion of three-components	1887:1952	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	9	47	theme	fitted	1891:1896	arg1	higher					1973:1978	higher	1973:1978	higher	1973:1978	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	5	48	theme	hemicellulose	1032:1044	arg1	combustion					1046:1055	cellulose and hemicellulose combustion	1018:1055	cellulose and hemicellulose combustion	1018:1055	The proportion of naphthalene emitted from cellulose and hemicellulose combustion is higher, while fluoranthene and pyrene accounted significantly higher proportion for lignin.					
36423835	4	49	theme	average	630:636	arg1	factors					647:653	The average emission factors	626:653	The average emission factors of the 16 kinds of PAHs	626:677	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	3	50	theme	EC	622:623	arg1	factors					576:582	emission factors	567:582	emission factors	567:582	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	3	50	theme	EC	622:623	arg1	compositions					597:608	chemical compositions	588:608	chemical compositions	588:608	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	3	51	theme	raw	466:468	arg1	materials					470:478	three typical biomass raw materials	444:478	three typical biomass raw materials	444:478	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	1	52	theme	hydrocarbons	218:229	arg1	burning					164:170	Biomass burning	156:170	Biomass burning	156:170	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	52	theme	hydrocarbons	218:229	arg1	source					188:193	an important source	175:193	an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC)	175:262	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	7	53	theme	temperature	1313:1323	arg1	significant					1364:1374	significant	1364:1374	significant	1364:1374	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	7	53	theme	temperature	1313:1323	arg1	influence					1291:1299	The influence	1287:1299	The influence of ignition temperature on the emission of EC and PAHs	1287:1354	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	4	54	theme	lignin	894:899	arg1	order					855:859	the descending order	840:859	the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	840:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	9	55	theme	three-components	1937:1952	arg1	proportion					1923:1932	the proportion	1919:1932	the proportion of three-components	1919:1952	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	3	56	theme	typical	450:456	arg1	materials					470:478	three typical biomass raw materials	444:478	three typical biomass raw materials	444:478	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	10	57	theme	formation	2115:2123	arg1	pathways					2125:2132	the different formation pathways	2101:2132	the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC	2101:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	5	58	theme	cellulose	1018:1026	arg1	combustion					1046:1055	cellulose and hemicellulose combustion	1018:1055	cellulose and hemicellulose combustion	1018:1055	The proportion of naphthalene emitted from cellulose and hemicellulose combustion is higher, while fluoranthene and pyrene accounted significantly higher proportion for lignin.					
36423835	4	59	theme	±	946:946	arg1	hemicellulose					925:937	hemicellulose	925:937	hemicellulose (0.450 ± 0.480 g/kg)	925:958	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	59	theme	±	946:946	arg1	g/kg					954:957	0.450 ± 0.480 g/kg	940:957	0.450 ± 0.480 g/kg	940:957	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	0	60	theme	PAHs	55:58	arg1	characteristics					9:23	Emission characteristics	0:23	Emission characteristics	0:23	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	0	60	theme	PAHs	55:58	arg1	mechanisms					41:50	influencing mechanisms	29:50	influencing mechanisms	29:50	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	9	61	theme	measured	1989:1996	arg1	values					1998:2003	the measured values	1985:2003	the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC	1985:2074	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	8	62	theme	ring	1762:1765	arg1	PAHs					1767:1770	4-6 ring PAHs	1758:1770	4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene)	1758:1828	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	3	63	theme	combustion	505:514	arg1	experiments					516:526	laboratory combustion experiments	494:526	laboratory combustion experiments	494:526	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	7	64	from	influence	1291:1299	arg1	emission					1332:1339	the emission	1328:1339	the emission of EC and PAHs	1328:1354	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	10	65	theme	EC	2179:2180	arg1	components					2182:2191	the two EC components	2171:2191	the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC	2171:2312	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	0	66	from	combustion	76:85	arg1	characteristics					9:23	Emission characteristics	0:23	Emission characteristics	0:23	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	0	66	from	combustion	76:85	arg1	mechanisms					41:50	influencing mechanisms	29:50	influencing mechanisms	29:50	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	9	67	theme	materials	2012:2020	arg1	values					1998:2003	the measured values	1985:2003	the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC	1985:2074	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	3	68	dep	factors	576:582	arg1	the					563:565	the	563:565	the	563:565	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	4	69	theme	average	796:802	arg1	factors					813:819	the average emission factors	792:819	the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	792:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	10	70	theme	biomass	2204:2210	arg1	worthy					2234:2239	worthy	2234:2239	worthy of further studies	2234:2258	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	10	70	theme	biomass	2204:2210	arg1	combustion					2212:2221	biomass combustion	2204:2221	biomass combustion	2204:2221	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	9	71	theme	medium-molecular-weight	2034:2056	arg1	PAHs					2058:2061	medium-molecular-weight PAHs	2034:2061	medium-molecular-weight PAHs	2034:2061	We also found that the fitted results according to the proportion of three-components were significantly higher than the measured values of raw materials for indene, medium-molecular-weight PAHs, and soot-EC.					
36423835	0	72	theme	biomasses	145:153	arg1	components					96:105	three components	90:105	three components (cellulose, hemicellulose, lignin) of biomasses	90:153	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	8	73	from	effects	1652:1658	arg1	growth					1667:1672	PAH growth	1663:1672	PAH growth	1663:1672	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	1	74	theme	polycyclic	198:207	arg1	hydrocarbons					218:229	polycyclic aromatic hydrocarbons	198:229	polycyclic aromatic hydrocarbons (PAHs)	198:236	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	74	theme	polycyclic	198:207	arg1	PAHs					232:235	PAHs	232:235	PAHs	232:235	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	6	75	theme	content	1211:1217	arg1	influence					1166:1174	the influence	1162:1174	the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC	1162:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	4	76	theme	descending	844:853	arg1	order					855:859	the descending order	840:859	the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	840:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	10	77	theme	studies	2252:2258	arg1	worthy					2234:2239	worthy	2234:2239	worthy of further studies	2234:2258	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	10	77	theme	studies	2252:2258	arg1	combustion					2212:2221	biomass combustion	2204:2221	biomass combustion	2204:2221	These results presented the different formation pathways for medium-molecular-weight PAHs and the two EC components emitted by biomass combustion, which are worthy of further studies in exploring the generation mechanisms of PAHs and EC.					
36423835	6	78	theme	ignition	1179:1186	arg1	temperature					1188:1198	ignition temperature	1179:1198	ignition temperature	1179:1198	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	8	79	theme	PAH	1663:1665	arg1	growth					1667:1672	PAH growth	1663:1672	PAH growth	1663:1672	However, correlation analysis combined with cluster analysis showed that the RSR-pathway probably had different effects on PAH growth for the three-components, as the indene-involved RSR-pathway were mainly related to 4-6 ring PAHs for cellulose and lignin (except fluoranthene and pyrene), but 2-4 ring PAHs for hemicellulose.					
36423835	4	80	theme	EC	824:825	arg1	factors					813:819	the average emission factors	792:819	the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively	792:972	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	80	theme	EC	824:825	arg1	mg/kg					780:784	48.9 ± 65.2 mg/kg	768:784	48.9 ± 65.2 mg/kg	768:784	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	80	theme	EC	824:825	arg1	hemicellulose					753:765	hemicellulose	753:765	hemicellulose (48.9 ± 65.2 mg/kg)	753:785	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	81	theme	±	880:880	arg1	g/kg					887:890	1.65 ± 3.02 g/kg	875:890	1.65 ± 3.02 g/kg	875:890	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	81	theme	±	880:880	arg1	cellulose					864:872	cellulose	864:872	cellulose (1.65 ± 3.02 g/kg)	864:891	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	82	theme	PAHs	674:677	arg1	kinds					665:669	the 16 kinds	658:669	the 16 kinds of PAHs	658:677	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	0	83	theme	influencing	29:39	arg1	mechanisms					41:50	influencing mechanisms	29:50	influencing mechanisms	29:50	Emission characteristics and influencing mechanisms of PAHs and EC from the combustion of three components (cellulose, hemicellulose, lignin) of biomasses.					
36423835	7	84	theme	reaction	1516:1523	arg1	pathway					1531:1537	resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway	1469:1537	resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway	1469:1537	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	3	85	from	differences	548:558	arg1	factors					576:582	emission factors	567:582	emission factors	567:582	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	3	85	from	differences	548:558	arg1	compositions					597:608	chemical compositions	588:608	chemical compositions	588:608	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	2	86	theme	major	364:368	arg1	lignin					343:348	lignin	343:348	lignin	343:348	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	86	theme	major	364:368	arg1	Cellulose					313:321	Cellulose	313:321	Cellulose	313:321	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	86	theme	major	364:368	arg1	hemicellulose					324:336	hemicellulose	324:336	hemicellulose	324:336	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	2	86	theme	major	364:368	arg1	components					370:379	the three major components	354:379	the three major components of biomass	354:390	Cellulose, hemicellulose, and lignin are the three major components of biomass.					
36423835	6	87	theme	PAHs	1254:1257	arg1	characteristics					1235:1249	the emission characteristics	1222:1249	the emission characteristics of PAHs and EC	1222:1264	Moreover, the influence of ignition temperature and oxygen content on the emission characteristics of PAHs and EC were also discussed.					
36423835	5	88	theme	naphthalene	993:1003	arg1	proportion					979:988	The proportion	975:988	The proportion of naphthalene emitted from cellulose and hemicellulose combustion	975:1055	The proportion of naphthalene emitted from cellulose and hemicellulose combustion is higher, while fluoranthene and pyrene accounted significantly higher proportion for lignin.					
36423835	5	88	theme	naphthalene	993:1003	arg1	higher					1060:1065	higher	1060:1065	higher	1060:1065	The proportion of naphthalene emitted from cellulose and hemicellulose combustion is higher, while fluoranthene and pyrene accounted significantly higher proportion for lignin.					
36423835	7	89	theme	hydrocarbon-radical	1490:1508	arg1	RSR					1526:1528	RSR	1526:1528	RSR	1526:1528	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	7	89	theme	hydrocarbon-radical	1490:1508	arg1	reaction					1516:1523	resonance-stabilized hydrocarbon-radical chain reaction	1469:1523	resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway	1469:1537	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	3	90	theme	chemical	588:595	arg1	compositions					597:608	chemical compositions	588:608	chemical compositions	588:608	In this study, the three-components extracted from three typical biomass raw materials were used for laboratory combustion experiments, to investigate the differences in the emission factors and chemical compositions of PAHs and EC.					
36423835	7	91	theme	PAHs	1351:1354	arg1	emission					1332:1339	the emission	1328:1339	the emission of EC and PAHs	1328:1354	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	1	92	theme	formation	273:281	arg1	mechanisms					283:292	the formation mechanisms	269:292	the formation mechanisms	269:292	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	92	theme	formation	273:281	arg1	unclear					304:310	unclear	304:310	unclear	304:310	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	7	93	theme	EC	1344:1345	arg1	emission					1332:1339	the emission	1328:1339	the emission of EC and PAHs	1328:1354	The influence of ignition temperature on the emission of EC and PAHs is more significant compared to oxygen content, because it obviously promoted the PAHs and EC formations through resonance-stabilized hydrocarbon-radical chain reaction (RSR) pathway.					
36423835	4	94	theme	±	907:907	arg1	g/kg					914:917	1.30 ± 1.04 g/kg	902:917	1.30 ± 1.04 g/kg	902:917	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	4	94	theme	±	907:907	arg1	lignin					894:899	lignin	894:899	lignin (1.30 ± 1.04 g/kg)	894:918	The average emission factors of the 16 kinds of PAHs were showing as lignin (135 ± 180 mg/kg) > cellulose (97.8 ± 124 mg/kg) > hemicellulose (48.9 ± 65.2 mg/kg), and the average emission factors of EC presented in the descending order of cellulose (1.65 ± 3.02 g/kg), lignin (1.30 ± 1.04 g/kg), and hemicellulose (0.450 ± 0.480 g/kg), respectively.					
36423835	1	95	theme	aromatic	209:216	arg1	hydrocarbons					218:229	polycyclic aromatic hydrocarbons	198:229	polycyclic aromatic hydrocarbons (PAHs)	198:236	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36423835	1	95	theme	aromatic	209:216	arg1	PAHs					232:235	PAHs	232:235	PAHs	232:235	Biomass burning is an important source of polycyclic aromatic hydrocarbons (PAHs) and elemental carbon (EC), but the formation mechanisms are still unclear.					
36446513	8	0	theme	wastewater	1251:1260	arg1	treatments					1262:1271	wastewater treatments	1251:1271	wastewater treatments	1251:1271	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	0	1	theme	selective	84:92	arg1	removal					94:100	selective removal	84:100	selective removal of methylene blue	84:118	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	6	2	theme	Freundlich	967:976	arg1	model					978:982	Freundlich model	967:982	Freundlich model	967:982	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	8	3	from	use	1244:1246	arg1	treatments					1262:1271	wastewater treatments	1251:1271	wastewater treatments	1251:1271	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	8	3	from	use	1244:1246	arg1	separation					1289:1298	intelligent separation	1277:1298	intelligent separation	1277:1298	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	0	4	theme	methylene	105:113	arg1	removal					94:100	selective removal	84:100	selective removal of methylene blue	84:118	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	7	5	theme	selective	1036:1044	arg1	capacity					1057:1064	selective adsorption capacity	1036:1064	selective adsorption capacity	1036:1064	The AlgMA/PNaSS cryogels also reveal selective adsorption capacity and reusability after regeneration, which own unchanged corrected adsorption capacity during five adsorption-desorption cycles.					
36446513	2	6	theme	dyes	320:323	arg1	removal					300:306	efficient removal	290:306	efficient removal of cationic dyes	290:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	5	7	with	AlgMA/PNaSS	739:749	arg1	ratio					764:768	a mass ratio	757:768	a mass ratio of 1:2	757:775	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	4	8	theme	thermal-initiated	646:662	arg1	polymerization					664:677	thermal-initiated polymerization	646:677	thermal-initiated polymerization	646:677	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	0	9	link	crosslinked	11:21	arg1	alginate/poly					30:42	Covalently crosslinked sodium alginate/poly	0:42	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate)	0:69	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	0	9	link	crosslinked	11:21	arg1	p-styrenesulfonate					51:68	sodium p-styrenesulfonate	44:68	sodium p-styrenesulfonate	44:68	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	2	10	theme	cationic	311:318	arg1	dyes					320:323	cationic dyes	311:323	cationic dyes	311:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	2	11	theme	radical	352:358	arg1	copolymerization					360:375	radical copolymerization	352:375	radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS)	352:449	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	3	12	theme	AlgMA/PNaSS	517:527	arg1	cryogels					529:536	the AlgMA/PNaSS cryogels	513:536	the AlgMA/PNaSS cryogels	513:536	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	3	13	theme	chemical	456:463	arg1	structure					465:473	The chemical structure	452:473	The chemical structure	452:473	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	4	14	theme	blue	729:732	arg1	methylene					719:727	methylene blue	719:732	methylene blue	719:732	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	0	15	theme	blue	115:118	arg1	methylene					105:113	methylene blue	105:118	methylene blue	105:118	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	5	16	contain	possesses	778:786	arg1	AlgMA/PNaSS					739:749	The AlgMA/PNaSS	735:749	The AlgMA/PNaSS (with a mass ratio of 1:2)	735:776	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	5	16	contain	possesses	778:786	arg2	capacity					811:818	the maximum adsorption capacity	788:818	the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition	788:865	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	4	17	theme	methylene	719:727	arg1	adsorption					705:714	higher adsorption	698:714	higher adsorption of methylene blue	698:732	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	0	18	theme	crosslinked	11:21	arg1	alginate/poly					30:42	Covalently crosslinked sodium alginate/poly	0:42	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate)	0:69	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	0	18	theme	crosslinked	11:21	arg1	p-styrenesulfonate					51:68	sodium p-styrenesulfonate	44:68	sodium p-styrenesulfonate	44:68	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	1	19	with	Adsorbents	121:130	arg1	sustainability					163:176	sustainability	163:176	sustainability	163:176	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	1	19	with	Adsorbents	121:130	arg1	reusability					183:193	reusability	183:193	reusability	183:193	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	1	19	with	Adsorbents	121:130	arg1	capacity					153:160	high adsorption capacity	137:160	high adsorption capacity	137:160	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	7	20	theme	AlgMA/PNaSS	1003:1013	arg1	cryogels					1015:1022	The AlgMA/PNaSS cryogels	999:1022	The AlgMA/PNaSS cryogels	999:1022	The AlgMA/PNaSS cryogels also reveal selective adsorption capacity and reusability after regeneration, which own unchanged corrected adsorption capacity during five adsorption-desorption cycles.					
36446513	4	21	with	hydrogels	587:595	arg1	composition					620:630	the same chemical composition	602:630	the same chemical composition fabricated by thermal-initiated polymerization	602:677	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	6	22	theme	order	951:955	arg1	model					957:961	the pseudo-second order model	933:961	the pseudo-second order model	933:961	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	2	23	theme	sodium	418:423	arg1	p-styrenesulfonate					425:442	sodium p-styrenesulfonate	418:442	sodium p-styrenesulfonate (NaSS)	418:449	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	2	23	theme	sodium	418:423	arg1	NaSS					445:448	NaSS	445:448	NaSS	445:448	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	8	24	theme	intelligent	1277:1287	arg1	separation					1289:1298	intelligent separation	1277:1298	intelligent separation	1277:1298	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	5	25	theme	mass	759:762	arg1	ratio					764:768	a mass ratio	757:768	a mass ratio of 1:2	757:775	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	3	26	theme	thermal	492:498	arg1	stability					500:508	thermal stability	492:508	thermal stability	492:508	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	0	27	theme	sodium	23:28	arg1	alginate/poly					30:42	Covalently crosslinked sodium alginate/poly	0:42	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate)	0:69	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	0	27	theme	sodium	23:28	arg1	p-styrenesulfonate					51:68	sodium p-styrenesulfonate	44:68	sodium p-styrenesulfonate	44:68	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	4	28	theme	chemical	611:618	arg1	composition					620:630	the same chemical composition	602:630	the same chemical composition fabricated by thermal-initiated polymerization	602:677	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	7	29	theme	adsorption-desorption	1164:1184	arg1	cycles					1186:1191	five adsorption-desorption cycles	1159:1191	five adsorption-desorption cycles	1159:1191	The AlgMA/PNaSS cryogels also reveal selective adsorption capacity and reusability after regeneration, which own unchanged corrected adsorption capacity during five adsorption-desorption cycles.					
36446513	1	30	theme	wastewater	210:219	arg1	treatments					221:230	wastewater treatments	210:230	wastewater treatments	210:230	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	0	31	theme	sodium	44:49	arg1	alginate/poly					30:42	Covalently crosslinked sodium alginate/poly	0:42	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate)	0:69	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	0	31	theme	sodium	44:49	arg1	p-styrenesulfonate					51:68	sodium p-styrenesulfonate	44:68	sodium p-styrenesulfonate	44:68	Covalently crosslinked sodium alginate/poly(sodium p-styrenesulfonate) cryogels for selective removal of methylene blue.					
36446513	4	32	theme	same	606:609	arg1	composition					620:630	the same chemical composition	602:630	the same chemical composition fabricated by thermal-initiated polymerization	602:677	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	8	33	theme	AlgMA/PNaSS	1198:1208	arg1	cryogels					1210:1217	The AlgMA/PNaSS cryogels	1194:1217	The AlgMA/PNaSS cryogels	1194:1217	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	6	34	theme	cryogels	919:926	arg1	process					896:902	the adsorption process	881:902	the adsorption process of AlgMA/PNaSS cryogels	881:926	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	2	35	theme	crosslinked	252:262	arg1	cryogels					276:283	covalently crosslinked microporous cryogels	241:283	covalently crosslinked microporous cryogels with efficient removal of cationic dyes	241:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	2	36	with	cryogels	276:283	arg1	removal					300:306	efficient removal	290:306	efficient removal of cationic dyes	290:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	5	37	theme	1:2	773:775	arg1	ratio					764:768	a mass ratio	757:768	a mass ratio of 1:2	757:775	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	6	38	theme	AlgMA/PNaSS	907:917	arg1	cryogels					919:926	AlgMA/PNaSS cryogels	907:926	AlgMA/PNaSS cryogels	907:926	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	5	39	theme	maximum	792:798	arg1	capacity					811:818	the maximum adsorption capacity	788:818	the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition	788:865	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	6	40	theme	pseudo-second	937:949	arg1	model					957:961	the pseudo-second order model	933:961	the pseudo-second order model	933:961	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	2	41	theme	methacrylated	383:395	arg1	AlgMA					407:411	AlgMA	407:411	AlgMA	407:411	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	2	41	theme	methacrylated	383:395	arg1	alginate					397:404	methacrylated alginate	383:404	methacrylated alginate (AlgMA)	383:412	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	5	42	theme	alkaline	848:855	arg1	condition					857:865	alkaline condition	848:865	alkaline condition	848:865	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	7	43	theme	adsorption	1132:1141	arg1	capacity					1143:1150	adsorption capacity	1132:1150	adsorption capacity during five adsorption-desorption cycles	1132:1191	The AlgMA/PNaSS cryogels also reveal selective adsorption capacity and reusability after regeneration, which own unchanged corrected adsorption capacity during five adsorption-desorption cycles.					
36446513	3	44	theme	cryogels	529:536	arg1	morphology					476:485	morphology	476:485	morphology	476:485	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	3	44	theme	cryogels	529:536	arg1	structure					465:473	The chemical structure	452:473	The chemical structure	452:473	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	3	44	theme	cryogels	529:536	arg1	stability					500:508	thermal stability	492:508	thermal stability	492:508	The chemical structure, morphology, and thermal stability of the AlgMA/PNaSS cryogels are characterized.					
36446513	4	45	theme	AlgMA/PNaSS	575:585	arg1	hydrogels					587:595	the AlgMA/PNaSS hydrogels	571:595	the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization	571:677	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	6	46	theme	adsorption	885:894	arg1	process					896:902	the adsorption process	881:902	the adsorption process of AlgMA/PNaSS cryogels	881:926	In addition, the adsorption process of AlgMA/PNaSS cryogels fits the pseudo-second order model and Freundlich model, respectively.					
36446513	2	47	theme	efficient	290:298	arg1	removal					300:306	efficient removal	290:306	efficient removal of cationic dyes	290:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	1	48	theme	high	137:140	arg1	capacity					153:160	high adsorption capacity	137:160	high adsorption capacity	137:160	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	8	49	theme	great	1224:1228	arg1	potential					1230:1238	great potential	1224:1238	great potential for use in wastewater treatments and intelligent separation	1224:1298	The AlgMA/PNaSS cryogels show great potential for use in wastewater treatments and intelligent separation.					
36446513	1	50	theme	adsorption	142:151	arg1	capacity					153:160	high adsorption capacity	137:160	high adsorption capacity	137:160	Adsorbents with high adsorption capacity, sustainability, and reusability are desired in wastewater treatments.					
36446513	5	51	theme	adsorption	800:809	arg1	capacity					811:818	the maximum adsorption capacity	788:818	the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition	788:865	The AlgMA/PNaSS (with a mass ratio of 1:2) possesses the maximum adsorption capacity for MB with 2300 mg/g under alkaline condition.					
36446513	4	52	theme	higher	698:703	arg1	adsorption					705:714	higher adsorption	698:714	higher adsorption of methylene blue	698:732	Compared with the AlgMA/PNaSS hydrogels with the same chemical composition fabricated by thermal-initiated polymerization, the cryogels show higher adsorption of methylene blue.					
36446513	2	53	link	crosslinked	252:262	arg1	cryogels					276:283	covalently crosslinked microporous cryogels	241:283	covalently crosslinked microporous cryogels with efficient removal of cationic dyes	241:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	2	54	theme	microporous	264:274	arg1	cryogels					276:283	covalently crosslinked microporous cryogels	241:283	covalently crosslinked microporous cryogels with efficient removal of cationic dyes	241:323	Herein, covalently crosslinked microporous cryogels with efficient removal of cationic dyes are fabricated by freezing radical copolymerization using methacrylated alginate (AlgMA) and sodium p-styrenesulfonate (NaSS).					
36446513	7	55	theme	adsorption	1046:1055	arg1	capacity					1057:1064	selective adsorption capacity	1036:1064	selective adsorption capacity	1036:1064	The AlgMA/PNaSS cryogels also reveal selective adsorption capacity and reusability after regeneration, which own unchanged corrected adsorption capacity during five adsorption-desorption cycles.					
36012648	0	0	theme	Thermal	88:94	arg1	Treatment					96:104	Thermal Treatment	88:104	Thermal Treatment	88:104	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	3	1	from	effect	382:387	arg1	morphology					413:422	morphology	413:422	morphology	413:422	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	3	1	from	effect	382:387	arg1	properties					433:442	texture properties	425:442	texture properties	425:442	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	3	1	from	effect	382:387	arg1	microstructure					453:466	the microstructure	449:466	the microstructure of the hydrogel	449:482	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	1	2	theme	novel	147:151	arg1	Salecan					128:134	Salecan	128:134	Salecan (Sal)	128:140	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	1	2	theme	novel	147:151	arg1	polysaccharide					170:183	a novel marine microbial polysaccharide	145:183	a novel marine microbial polysaccharide	145:183	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	1	3	theme	marine	153:158	arg1	Salecan					128:134	Salecan	128:134	Salecan (Sal)	128:140	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	1	3	theme	marine	153:158	arg1	polysaccharide					170:183	a novel marine microbial polysaccharide	145:183	a novel marine microbial polysaccharide	145:183	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	7	4	theme	FTIR	848:851	arg1	results					861:867	FTIR and XRD results	848:867	FTIR and XRD results	848:867	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	4	5	theme	wt	543:544	arg1	%					545:545	0.4 to 0.6 wt%	532:545	0.4 to 0.6 wt%	532:545	As Sal concentration varied from 0.4 to 0.6 wt%, hydrogel elasticity increased from 0.49 to 0.85 mm.					
36012648	6	6	theme	elastic	782:788	arg1	hydrogel					790:797	Sal-SPI elastic hydrogel	774:797	Sal-SPI elastic hydrogel	774:797	Rheological studies showed that Sal-SPI elastic hydrogel formed under the gelation process.					
36012648	4	7	theme	hydrogel	548:555	arg1	elasticity					557:566	hydrogel elasticity	548:566	hydrogel elasticity	548:566	As Sal concentration varied from 0.4 to 0.6 wt%, hydrogel elasticity increased from 0.49 to 0.85 mm.					
36012648	4	8	dep	0.6	539:541	arg1	to					536:537	to	536:537	to	536:537	As Sal concentration varied from 0.4 to 0.6 wt%, hydrogel elasticity increased from 0.49 to 0.85 mm.					
36012648	5	9	theme	internal	617:624	arg1	structure					634:642	the internal network structure	613:642	the internal network structure of Sal-SPI composite hydrogel	613:672	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	6	10	theme	Sal-SPI	774:780	arg1	hydrogel					790:797	Sal-SPI elastic hydrogel	774:797	Sal-SPI elastic hydrogel	774:797	Rheological studies showed that Sal-SPI elastic hydrogel formed under the gelation process.					
36012648	3	11	theme	hydrogel	475:482	arg1	morphology					413:422	morphology	413:422	morphology	413:422	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	3	11	theme	hydrogel	475:482	arg1	properties					433:442	texture properties	425:442	texture properties	425:442	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	3	11	theme	hydrogel	475:482	arg1	microstructure					453:466	the microstructure	449:466	the microstructure of the hydrogel	449:482	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	1	12	theme	microbial	160:168	arg1	Salecan					128:134	Salecan	128:134	Salecan (Sal)	128:140	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	1	12	theme	microbial	160:168	arg1	polysaccharide					170:183	a novel marine microbial polysaccharide	145:183	a novel marine microbial polysaccharide	145:183	Salecan (Sal) is a novel marine microbial polysaccharide.					
36012648	8	13	theme	green	1032:1036	arg1	method					1049:1054	a green and simple method	1030:1054	a green and simple method to fabricate Sal-SPI double network hydrogels	1030:1100	This research supplied a green and simple method to fabricate Sal-SPI double network hydrogels.					
36012648	7	14	theme	SPI	925:927	arg1	molecules					929:937	SPI molecules	925:937	SPI molecules	925:937	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	3	15	theme	concentration	396:408	arg1	effect					382:387	The effect	378:387	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel	378:482	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	8	16	theme	simple	1042:1047	arg1	method					1049:1054	a green and simple method	1030:1054	a green and simple method to fabricate Sal-SPI double network hydrogels	1030:1100	This research supplied a green and simple method to fabricate Sal-SPI double network hydrogels.					
36012648	6	17	theme	Rheological	742:752	arg1	studies					754:760	Rheological studies	742:760	Rheological studies	742:760	Rheological studies showed that Sal-SPI elastic hydrogel formed under the gelation process.					
36012648	2	18	theme	transglutaminase	349:364	arg1	induction					366:374	transglutaminase induction	349:374	transglutaminase induction	349:374	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	8	19	theme	Sal-SPI	1069:1075	arg1	hydrogels					1092:1100	Sal-SPI double network hydrogels	1069:1100	Sal-SPI double network hydrogels	1069:1100	This research supplied a green and simple method to fabricate Sal-SPI double network hydrogels.					
36012648	5	20	theme	composite	655:663	arg1	hydrogel					665:672	Sal-SPI composite hydrogel	647:672	Sal-SPI composite hydrogel	647:672	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	2	21	dep	process	318:324	arg1	treatment					335:343	thermal treatment	327:343	thermal treatment	327:343	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	2	21	dep	process	318:324	arg1	induction					366:374	transglutaminase induction	349:374	transglutaminase induction	349:374	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	5	22	theme	hydrogel	665:672	arg1	structure					634:642	the internal network structure	613:642	the internal network structure of Sal-SPI composite hydrogel	613:672	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	2	23	theme	Sal-SPI	271:277	arg1	hydrogel					289:296	Sal-SPI composite hydrogel	271:296	Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction)	271:375	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	0	24	theme	Protein	42:48	arg1	Hydrogel					68:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	8	25	theme	double	1077:1082	arg1	hydrogels					1092:1100	Sal-SPI double network hydrogels	1069:1100	Sal-SPI double network hydrogels	1069:1100	This research supplied a green and simple method to fabricate Sal-SPI double network hydrogels.					
36012648	2	26	theme	protein	223:229	arg1	SPI					240:242	SPI	240:242	SPI	240:242	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	2	26	theme	protein	223:229	arg1	isolate					231:237	soy protein isolate	219:237	soy protein isolate (SPI)	219:243	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	3	27	theme	texture	425:431	arg1	properties					433:442	texture properties	425:442	texture properties	425:442	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	0	28	theme	Salecan-Soy	30:40	arg1	Hydrogel					68:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	4	29	theme	Sal	502:504	arg1	concentration					506:518	Sal concentration	502:518	Sal concentration	502:518	As Sal concentration varied from 0.4 to 0.6 wt%, hydrogel elasticity increased from 0.49 to 0.85 mm.					
36012648	3	30	theme	Sal	392:394	arg1	concentration					396:408	Sal concentration	392:408	Sal concentration	392:408	The effect of Sal concentration on morphology, texture properties, and the microstructure of the hydrogel was evaluated.					
36012648	2	31	theme	soy	219:221	arg1	SPI					240:242	SPI	240:242	SPI	240:242	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	2	31	theme	soy	219:221	arg1	isolate					231:237	soy protein isolate	219:237	soy protein isolate (SPI)	219:243	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	7	32	theme	structure	996:1004	arg1	formation					954:962	the formation	950:962	the formation of the interpenetrating network structure	950:1004	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	0	33	theme	Composite	58:66	arg1	Hydrogel					68:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	5	34	theme	network	626:632	arg1	structure					634:642	the internal network structure	613:642	the internal network structure of Sal-SPI composite hydrogel	613:672	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	5	35	theme	Sal	713:715	arg1	concentration					717:729	Sal concentration	713:729	Sal concentration	713:729	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	4	36	dep	0.85	591:594	arg1	to					588:589	to	588:589	to	588:589	As Sal concentration varied from 0.4 to 0.6 wt%, hydrogel elasticity increased from 0.49 to 0.85 mm.					
36012648	0	37	theme	Isolate	50:56	arg1	Hydrogel					68:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Salecan-Soy Protein Isolate Composite Hydrogel	30:75	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	8	38	theme	network	1084:1090	arg1	hydrogels					1092:1100	Sal-SPI double network hydrogels	1069:1100	Sal-SPI double network hydrogels	1069:1100	This research supplied a green and simple method to fabricate Sal-SPI double network hydrogels.					
36012648	6	39	theme	gelation	816:823	arg1	process					825:831	the gelation process	812:831	the gelation process	812:831	Rheological studies showed that Sal-SPI elastic hydrogel formed under the gelation process.					
36012648	7	40	theme	interpenetrating	971:986	arg1	structure					996:1004	the interpenetrating network structure	967:1004	the interpenetrating network structure	967:1004	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	2	41	theme	stepwise	309:316	arg1	process					318:324	a stepwise process	307:324	a stepwise process (thermal treatment and transglutaminase induction)	307:375	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	7	42	theme	hydrogen	887:894	arg1	bonds					896:900	hydrogen bonds	887:900	hydrogen bonds	887:900	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	7	43	theme	network	988:994	arg1	structure					996:1004	the interpenetrating network structure	967:1004	the interpenetrating network structure	967:1004	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36012648	2	44	theme	composite	279:287	arg1	hydrogel					289:296	Sal-SPI composite hydrogel	271:296	Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction)	271:375	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	5	45	theme	Sal-SPI	647:653	arg1	hydrogel					665:672	Sal-SPI composite hydrogel	647:672	Sal-SPI composite hydrogel	647:672	Furthermore, the internal network structure of Sal-SPI composite hydrogel also became denser and more uniform as Sal concentration increased.					
36012648	2	46	theme	present	193:199	arg1	research					201:208	the present research	189:208	the present research	189:208	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	2	47	theme	thermal	327:333	arg1	treatment					335:343	thermal treatment	327:343	thermal treatment	327:343	In the present research, Sal and soy protein isolate (SPI) were adopted to fabricate Sal-SPI composite hydrogel based on a stepwise process (thermal treatment and transglutaminase induction).					
36012648	0	48	theme	Hydrogel	68:75	arg1	Properties					16:25	Properties	16:25	Properties	16:25	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	0	48	theme	Hydrogel	68:75	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Properties of Salecan-Soy Protein Isolate Composite Hydrogel Induced by Thermal Treatment and Transglutaminase.					
36012648	7	49	theme	XRD	857:859	arg1	results					861:867	FTIR and XRD results	848:867	FTIR and XRD results	848:867	Additionally, FTIR and XRD results demonstrated that hydrogen bonds formed between Sal and SPI molecules, inferring the formation of the interpenetrating network structure.					
36346263	0	0	theme	behavior	103:110	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	0	0	theme	behavior	103:110	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	0	1	from	characterization	14:29	arg1	fluid					133:137	simulated gastric fluid	115:137	simulated gastric fluid	115:137	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	7	2	theme	simulated	1168:1176	arg1	fluid					1186:1190	vitro simulated gastric fluid	1162:1190	vitro simulated gastric fluid	1162:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	8	3	from	fortification	1295:1307	arg1	food					1312:1315	food	1312:1315	food	1312:1315	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	2	4	dep	in	310:311	arg1	situ					313:316	situ	313:316	situ	313:316	Herein, CNC-Fe nanoparticles were successfully prepared via an in situ chemical reduction approach.					
36346263	0	5	theme	digestion	93:101	arg1	behavior					103:110	their digestion behavior	87:110	their digestion behavior	87:110	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	7	6	theme	gastric	1178:1184	arg1	fluid					1186:1190	vitro simulated gastric fluid	1162:1190	vitro simulated gastric fluid	1162:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	8	7	theme	loading	1258:1264	arg1	Fe					1266:1267	loading Fe	1258:1267	loading Fe into nanoparticles for Fe fortification in food	1258:1315	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	1	8	theme	great	177:181	arg1	potential					183:191	great potential	177:191	great potential	177:191	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	8	theme	great	177:181	arg1	template					237:244	a food emulsifier or functional material template	196:244	a food emulsifier or functional material template	196:244	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	0	9	theme	simulated	115:123	arg1	fluid					133:137	simulated gastric fluid	115:137	simulated gastric fluid	115:137	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	0	10	from	Synthesis	0:8	arg1	fluid					133:137	simulated gastric fluid	115:137	simulated gastric fluid	115:137	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	6	11	theme	photoelectron	888:900	arg1	spectroscopy					902:913	X-ray photoelectron spectroscopy	882:913	X-ray photoelectron spectroscopy	882:913	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	2	12	theme	in	310:311	arg1	approach					337:344	an in situ chemical reduction approach	307:344	an in situ chemical reduction approach	307:344	Herein, CNC-Fe nanoparticles were successfully prepared via an in situ chemical reduction approach.					
36346263	3	13	theme	magnetic	394:401	arg1	resonance					403:411	low-field nuclear magnetic resonance	376:411	low-field nuclear magnetic resonance spectroscopy	376:424	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	6	14	theme	valence	934:940	arg1	ferrous					996:1002	ferrous	996:1002	ferrous	996:1002	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	6	14	theme	valence	934:940	arg1	state					942:946	the valence state	930:946	the valence state of Fe in CNC-Fe nanoparticles	930:976	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	7	15	theme	vitro	1162:1166	arg1	fluid					1186:1190	vitro simulated gastric fluid	1162:1190	vitro simulated gastric fluid	1162:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	4	16	theme	spherical	615:623	arg1	nanoparticles					625:637	small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles	582:637	small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC	582:682	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	4	17	dep	small	582:586	arg1	diameter = 10.0 ± 2.4 nm					589:612	diameter = 10.0 ± 2.4 nm	589:612	diameter = 10.0 ± 2.4 nm	589:612	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	7	18	theme	spontaneous	1135:1145	arg1	dissolution					1147:1157	complete, rapid, and spontaneous dissolution	1114:1157	complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid	1114:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	7	19	from	stability	1075:1083	arg1	dispersion					1090:1099	a dispersion	1088:1099	a dispersion for 21 d	1088:1108	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	7	19	from	stability	1075:1083	arg1	fluid					1186:1190	vitro simulated gastric fluid	1162:1190	vitro simulated gastric fluid	1162:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	3	20	theme	CNC	529:531	arg1	dispersion					533:542	a CNC dispersion	527:542	a CNC dispersion	527:542	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	0	21	theme	gastric	125:131	arg1	fluid					133:137	simulated gastric fluid	115:137	simulated gastric fluid	115:137	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	5	22	dep	Fourier	725:731	arg1	transform					733:741	transform	733:741	transform infrared spectroscopy	733:763	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	8	23	theme	CNC	1236:1238	arg1	template					1245:1252	a template	1243:1252	a template for loading Fe into nanoparticles for Fe fortification in food	1243:1315	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	8	23	theme	CNC	1236:1238	arg1	use					1229:1231	the potential use	1215:1231	the potential use of CNC	1215:1238	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	3	24	theme	Zeta	347:350	arg1	measurements					362:373	Zeta potential measurements	347:373	Zeta potential measurements	347:373	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	5	25	theme	intense	777:783	arg1	peak					785:788	an intense peak	774:788	an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations	774:879	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	3	26	theme	force	438:442	arg1	microscopy					444:453	atomic force microscopy	431:453	atomic force microscopy	431:453	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	8	27	theme	Fe	1292:1293	arg1	fortification					1295:1307	Fe fortification	1292:1307	Fe fortification in food	1292:1315	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	8	28	theme	potential	1219:1227	arg1	template					1245:1252	a template	1243:1252	a template for loading Fe into nanoparticles for Fe fortification in food	1243:1315	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	8	28	theme	potential	1219:1227	arg1	use					1229:1231	the potential use	1215:1231	the potential use of CNC	1215:1238	Our results highlight the potential use of CNC as a template for loading Fe into nanoparticles for Fe fortification in food.					
36346263	2	29	theme	reduction	327:335	arg1	approach					337:344	an in situ chemical reduction approach	307:344	an in situ chemical reduction approach	307:344	Herein, CNC-Fe nanoparticles were successfully prepared via an in situ chemical reduction approach.					
36346263	1	30	theme	food	198:201	arg1	template					237:244	a food emulsifier or functional material template	196:244	a food emulsifier or functional material template	196:244	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	30	theme	food	198:201	arg1	potential					183:191	great potential	177:191	great potential	177:191	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	3	31	theme	resonance	403:411	arg1	spectroscopy					413:424	low-field nuclear magnetic resonance spectroscopy	376:424	low-field nuclear magnetic resonance spectroscopy	376:424	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	6	32	from	state	942:946	arg1	nanoparticles					964:976	CNC-Fe nanoparticles	957:976	CNC-Fe nanoparticles	957:976	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	2	33	theme	chemical	318:325	arg1	approach					337:344	an in situ chemical reduction approach	307:344	an in situ chemical reduction approach	307:344	Herein, CNC-Fe nanoparticles were successfully prepared via an in situ chemical reduction approach.					
36346263	1	34	theme	emulsifier	203:212	arg1	template					237:244	a food emulsifier or functional material template	196:244	a food emulsifier or functional material template	196:244	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	34	theme	emulsifier	203:212	arg1	potential					183:191	great potential	177:191	great potential	177:191	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	7	35	theme	excellent	1055:1063	arg1	stability					1075:1083	excellent colloidal stability	1055:1083	excellent colloidal stability in a dispersion for 21 d	1055:1108	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	7	36	theme	rapid	1124:1128	arg1	dissolution					1147:1157	complete, rapid, and spontaneous dissolution	1114:1157	complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid	1114:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	6	37	theme	Fe	951:952	arg1	ferrous					996:1002	ferrous	996:1002	ferrous	996:1002	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	6	37	theme	Fe	951:952	arg1	state					942:946	the valence state	930:946	the valence state of Fe in CNC-Fe nanoparticles	930:976	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	5	38	theme	FeO	855:857	arg1	vibrations					870:879	FeO stretching vibrations	855:879	FeO stretching vibrations	855:879	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	0	39	theme	nanocrystal-Fe	44:57	arg1	nanoparticles					69:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	4	40	theme	ions	719:722	arg1	reduction					694:702	the reduction	690:702	the reduction of the Fe(III) ions	690:722	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	5	41	theme	stretching	859:868	arg1	vibrations					870:879	FeO stretching vibrations	855:879	FeO stretching vibrations	855:879	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	3	42	theme	Fe	467:468	arg1	ions					475:478	Fe(III) ions	467:478	Fe(III) ions	467:478	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	1	43	theme	functional	217:226	arg1	template					237:244	a food emulsifier or functional material template	196:244	a food emulsifier or functional material template	196:244	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	43	theme	functional	217:226	arg1	potential					183:191	great potential	177:191	great potential	177:191	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	0	44	theme	cellulose	34:42	arg1	nanoparticles					69:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	7	45	theme	complete	1114:1121	arg1	dissolution					1147:1157	complete, rapid, and spontaneous dissolution	1114:1157	complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid	1114:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	6	46	theme	X-ray	882:886	arg1	spectroscopy					902:913	X-ray photoelectron spectroscopy	882:913	X-ray photoelectron spectroscopy	882:913	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	4	47	theme	small	582:586	arg1	nanoparticles					625:637	small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles	582:637	small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC	582:682	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	1	48	theme	material	228:235	arg1	template					237:244	a food emulsifier or functional material template	196:244	a food emulsifier or functional material template	196:244	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	48	theme	material	228:235	arg1	potential					183:191	great potential	177:191	great potential	177:191	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	0	49	theme	nanoparticles	69:81	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	0	49	theme	nanoparticles	69:81	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	3	50	theme	nuclear	386:392	arg1	resonance					403:411	low-field nuclear magnetic resonance	376:411	low-field nuclear magnetic resonance spectroscopy	376:424	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	5	51	dep	transform	733:741	arg1	infrared					743:750	infrared	743:750	transform infrared spectroscopy	733:763	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	0	52	theme	composite	59:67	arg1	nanoparticles					69:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	cellulose nanocrystal-Fe composite nanoparticles	34:81	Synthesis and characterization of cellulose nanocrystal-Fe composite nanoparticles and their digestion behavior in simulated gastric fluid.					
36346263	4	53	theme	Micromorphological	545:562	arg1	analysis					564:571	Micromorphological analysis	545:571	Micromorphological analysis	545:571	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	3	54	theme	low-field	376:384	arg1	resonance					403:411	low-field nuclear magnetic resonance	376:411	low-field nuclear magnetic resonance spectroscopy	376:424	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	5	55	from	779 cm-1	793:800	arg1	peak					785:788	an intense peak	774:788	an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations	774:879	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	5	55	from	779 cm-1	793:800	arg1	nanoparticles					816:828	the CNC-Fe nanoparticles	805:828	the CNC-Fe nanoparticles	805:828	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	7	56	theme	colloidal	1065:1073	arg1	stability					1075:1083	excellent colloidal stability	1055:1083	excellent colloidal stability in a dispersion for 21 d	1055:1108	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	1	57	theme	Cellulose	140:148	arg1	nanocrystals					150:161	Cellulose nanocrystals	140:161	Cellulose nanocrystals (CNC)	140:167	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	1	57	theme	Cellulose	140:148	arg1	CNC					164:166	CNC	164:166	CNC	164:166	Cellulose nanocrystals (CNC) exhibit great potential as a food emulsifier or functional material template.					
36346263	6	58	theme	CNC-Fe	957:962	arg1	nanoparticles					964:976	CNC-Fe nanoparticles	957:976	CNC-Fe nanoparticles	957:976	X-ray photoelectron spectroscopy indicated that the valence state of Fe in CNC-Fe nanoparticles was predominantly ferrous.					
36346263	5	59	theme	CNC-Fe	809:814	arg1	nanoparticles					816:828	the CNC-Fe nanoparticles	805:828	the CNC-Fe nanoparticles	805:828	Fourier transform infrared spectroscopy revealed an intense peak at 779 cm-1 in the CNC-Fe nanoparticles, which was attributed to FeO stretching vibrations.					
36346263	7	60	theme	synthesized	1009:1019	arg1	nanoparticles					1028:1040	The synthesized CNC-Fe nanoparticles	1005:1040	The synthesized CNC-Fe nanoparticles	1005:1040	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	7	61	from	dissolution	1147:1157	arg1	fluid					1186:1190	vitro simulated gastric fluid	1162:1190	vitro simulated gastric fluid	1162:1190	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	7	61	from	dissolution	1147:1157	arg1	dispersion					1090:1099	a dispersion	1088:1099	a dispersion for 21 d	1088:1108	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	3	62	theme	potential	352:360	arg1	measurements					362:373	Zeta potential measurements	347:373	Zeta potential measurements	347:373	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	4	63	theme	CNC	680:682	arg1	surface					658:664	the surface	654:664	the surface of aggregated CNC	654:682	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	4	64	theme	aggregated	669:678	arg1	CNC					680:682	aggregated CNC	669:682	aggregated CNC	669:682	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36346263	3	65	theme	atomic	431:436	arg1	microscopy					444:453	atomic force microscopy	431:453	atomic force microscopy	431:453	Zeta potential measurements, low-field nuclear magnetic resonance spectroscopy, and atomic force microscopy showed that Fe(III) ions were adsorbed onto CNC when FeCl3 was added to a CNC dispersion.					
36346263	2	66	theme	CNC-Fe	255:260	arg1	nanoparticles					262:274	CNC-Fe nanoparticles	255:274	CNC-Fe nanoparticles	255:274	Herein, CNC-Fe nanoparticles were successfully prepared via an in situ chemical reduction approach.					
36346263	7	67	theme	CNC-Fe	1021:1026	arg1	nanoparticles					1028:1040	The synthesized CNC-Fe nanoparticles	1005:1040	The synthesized CNC-Fe nanoparticles	1005:1040	The synthesized CNC-Fe nanoparticles demonstrated excellent colloidal stability in a dispersion for 21 d and complete, rapid, and spontaneous dissolution in vitro simulated gastric fluid.					
36346263	4	68	theme	Fe	711:712	arg1	ions					719:722	the Fe(III) ions	707:722	the Fe(III) ions	707:722	Micromorphological analysis revealed small (diameter = 10.0 ± 2.4 nm) spherical nanoparticles synthesized on the surface of aggregated CNC after the reduction of the Fe(III) ions.					
36510012	3	0	theme	female	643:648	arg1	offspring					650:658	their female offspring	637:658	their female offspring	637:658	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	3	1	theme	study	469:473	arg1	objective					444:452	The objective	440:452	The objective of the present study	440:473	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	3	2	from	effects	495:501	arg1	populations					606:616	microbial populations	596:616	microbial populations	596:616	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	3	2	from	effects	495:501	arg1	glycemia					566:573	glycemia	566:573	glycemia	566:573	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	3	2	from	effects	495:501	arg1	profiles					582:589	lipid profiles	576:589	lipid profiles	576:589	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	0	3	theme	pesticide	65:73	arg1	combination					30:40	a combination	28:40	a combination of a high-fat diet and pesticide	28:73	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	1	4	theme	microbiota	321:330	arg1	perturbation					301:312	perturbation	301:312	perturbation of the microbiota	301:330	PURPOSE Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota.					
36510012	5	5	theme	CPF	929:931	arg1	combination					904:914	a combination	902:914	a combination of a HFD and CPF	902:931	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	9	6	theme	exposure	1379:1386	arg1	impact					1369:1374	the impact	1365:1374	the impact of exposure to a HFD alone but not that of CPF + HFD co-exposure	1365:1439	Inulin mitigated the impact of exposure to a HFD alone but not that of CPF + HFD co-exposure.					
36510012	0	7	theme	metabolic	87:95	arg1	status					113:118	the metabolic and microbiotic status	83:118	the metabolic and microbiotic status of dams and pups	83:135	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	10	8	theme	early	1569:1573	arg1	life					1575:1578	early life	1569:1578	early life	1569:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	8	9	theme	CPF + HFD	1227:1235	arg1	RESULTS					1202:1208	RESULTS	1202:1208	RESULTS HFD exposure and CPF + HFD co-exposure	1202:1247	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	8	9	theme	CPF + HFD	1227:1235	arg1	co-exposure					1237:1247	CPF + HFD co-exposure	1227:1247	CPF + HFD co-exposure	1227:1247	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	5	10	dep	HFD	921:923	arg1	a					919:919	a	919:919	a	919:919	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	7	11	theme	exposures	1071:1079	arg1	impacts					1054:1060	the impacts	1050:1060	the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues)	1050:1199	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	5	12	from	4 months	757:764	arg1	METHODS					744:750	METHODS	744:750	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams	744:836	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	3	13	theme	perigestational	506:520	arg1	exposure					522:529	perigestational exposure	506:529	perigestational exposure to a HFD and chlorpyrifos (CPF)	506:561	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	2	14	theme	risk	337:340	arg1	factors					342:348	The risk factors	333:348	The risk factors for metabolic disorders	333:372	The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues.					
36510012	8	15	from	imbalance	1278:1286	arg1	flora					1299:1303	the gut flora	1291:1303	the gut flora	1291:1303	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	0	16	theme	microbiotic	101:111	arg1	status					113:118	the metabolic and microbiotic status	83:118	the metabolic and microbiotic status of dams and pups	83:135	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	6	17	theme	female	969:974	arg1	offspring					976:984	All female offspring	965:984	All female offspring	965:984	All female offspring were fed a standard diet from weaning to adulthood.					
36510012	8	18	theme	HFD	1210:1212	arg1	RESULTS					1202:1208	RESULTS	1202:1208	RESULTS HFD exposure and CPF + HFD co-exposure	1202:1247	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	8	18	theme	HFD	1210:1212	arg1	exposure					1214:1221	HFD exposure	1210:1221	HFD exposure	1210:1221	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	10	19	theme	interactions	1511:1522	arg1	understanding					1482:1494	a better understanding	1473:1494	a better understanding of the complex interactions between environmental pollutants and diet in early life	1473:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	10	20	from	life	1575:1578	arg1	understanding					1482:1494	a better understanding	1473:1494	a better understanding of the complex interactions between environmental pollutants and diet in early life	1473:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	7	21	dep	microbiota	1121:1130	arg1	production					1157:1166	metabolite production	1146:1166	metabolite production	1146:1166	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	7	21	dep	microbiota	1121:1130	arg1	translocation					1173:1185	translocation	1173:1185	translocation into tissues	1173:1198	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	7	21	dep	microbiota	1121:1130	arg1	composition					1133:1143	composition	1133:1143	composition	1133:1143	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	8	22	dep	dams	1317:1320	arg1	the					1313:1315	the	1313:1315	the	1313:1315	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	10	23	theme	metabolic	1609:1617	arg1	diseases					1619:1626	metabolic diseases	1609:1626	metabolic diseases	1609:1626	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	5	24	theme	lactation	801:809	arg1	period					811:816	the lactation period	797:816	the lactation period	797:816	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	0	25	theme	Perigestational	0:14	arg1	exposure					16:23	Perigestational exposure	0:23	Perigestational exposure of a combination of a high-fat diet and pesticide	0:73	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	2	26	theme	metabolic	354:362	arg1	disorders					364:372	metabolic disorders	354:372	metabolic disorders	354:372	The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues.					
36510012	8	27	theme	female	1330:1335	arg1	offspring					1337:1345	the female offspring	1326:1345	the female offspring	1326:1345	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	4	28	with	treatment	707:715	arg1	inulin					736:741	the prebiotic inulin	722:741	the prebiotic inulin	722:741	We also tested a preventive strategy based on treatment with the prebiotic inulin.					
36510012	10	29	dep	CONCLUSION	1442:1451	arg1	provide					1465:1471	provide	1465:1471	provide	1465:1471	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	3	30	theme	exposure	522:529	arg1	effects					495:501	the effects	491:501	the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations	491:616	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	10	31	theme	complex	1503:1509	arg1	interactions					1511:1522	the complex interactions	1499:1522	the complex interactions between environmental pollutants and diet in early life	1499:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	1	32	theme	type-2	268:273	arg1	diabetes					275:282	type-2 diabetes	268:282	type-2 diabetes	268:282	PURPOSE Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota.					
36510012	7	33	from	impacts	1054:1060	arg1	microbiota					1121:1130	the microbiota	1117:1130	the microbiota (composition, metabolite production, and translocation into tissues)	1117:1199	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	7	33	from	impacts	1054:1060	arg1	profile					1104:1110	the lipid profile	1094:1110	the lipid profile	1094:1110	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	7	33	from	impacts	1054:1060	arg1	glycemia					1084:1091	glycemia	1084:1091	glycemia	1084:1091	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	4	34	theme	preventive	678:687	arg1	strategy					689:696	a preventive strategy	676:696	a preventive strategy based on treatment with the prebiotic inulin	676:741	We also tested a preventive strategy based on treatment with the prebiotic inulin.					
36510012	1	35	theme	PURPOSE	181:187	arg1	changes					199:205	PURPOSE Metabolic changes	181:205	PURPOSE Metabolic changes during the perinatal period	181:233	PURPOSE Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota.					
36510012	6	36	theme	standard	997:1004	arg1	diet					1006:1009	a standard diet	995:1009	a standard diet	995:1009	All female offspring were fed a standard diet from weaning to adulthood.					
36510012	5	37	theme	inulin	941:946	arg1	supplementation					948:962	inulin supplementation	941:962	inulin supplementation	941:962	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	9	38	theme	CPF + HFD	1419:1427	arg1	co-exposure					1429:1439	CPF + HFD co-exposure	1419:1439	CPF + HFD co-exposure	1419:1439	Inulin mitigated the impact of exposure to a HFD alone but not that of CPF + HFD co-exposure.					
36510012	5	39	theme	period	811:816	arg1	end					790:792	the end	786:792	the end of the lactation period	786:816	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	1	40	theme	Metabolic	189:197	arg1	changes					199:205	PURPOSE Metabolic changes	181:205	PURPOSE Metabolic changes during the perinatal period	181:233	PURPOSE Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota.					
36510012	0	41	theme	combination	30:40	arg1	exposure					16:23	Perigestational exposure	0:23	Perigestational exposure of a combination of a high-fat diet and pesticide	0:73	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	8	42	dep	RESULTS	1202:1208	arg1	RESULTS					1202:1208	RESULTS	1202:1208	RESULTS HFD exposure and CPF + HFD co-exposure	1202:1247	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	8	42	dep	RESULTS	1202:1208	arg1	exposure					1214:1221	HFD exposure	1210:1221	HFD exposure	1210:1221	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	8	42	dep	RESULTS	1202:1208	arg1	co-exposure					1237:1247	CPF + HFD co-exposure	1227:1247	CPF + HFD co-exposure	1227:1247	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	0	43	theme	dams	123:126	arg1	status					113:118	the metabolic and microbiotic status	83:118	the metabolic and microbiotic status of dams and pups	83:135	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	3	44	theme	lipid	576:580	arg1	profiles					582:589	lipid profiles	576:589	lipid profiles	576:589	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	10	45	from	understanding	1482:1494	arg1	life					1575:1578	early life	1569:1578	early life	1569:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	2	46	theme	high-fat	384:391	arg1	diet					393:396	a high-fat diet	382:396	a high-fat diet (HFD)	382:402	The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues.					
36510012	2	46	theme	high-fat	384:391	arg1	HFD					399:401	HFD	399:401	HFD	399:401	The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues.					
36510012	0	47	theme	high-fat	47:54	arg1	diet					56:59	a high-fat diet	45:59	a high-fat diet	45:59	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	10	48	theme	better	1475:1480	arg1	understanding					1482:1494	a better understanding	1473:1494	a better understanding of the complex interactions between environmental pollutants and diet in early life	1473:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	5	49	theme	dams	833:836	arg1	groups					823:828	six groups	819:828	six groups of dams	819:836	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	5	49	theme	dams	833:836	arg1	4 months					757:764	4 months	757:764	4 months before gestation to the end of the lactation period	757:816	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	5	49	theme	dams	833:836	arg1	dams					833:836	dams	833:836	dams	833:836	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	2	50	theme	pesticide	420:428	arg1	residues					430:437	pesticide residues	420:437	pesticide residues	420:437	The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues.					
36510012	0	51	theme	pups	132:135	arg1	status					113:118	the metabolic and microbiotic status	83:118	the metabolic and microbiotic status of dams and pups	83:135	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	5	52	theme	HFD	921:923	arg1	combination					904:914	a combination	902:914	a combination of a HFD and CPF	902:931	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	3	53	theme	present	461:467	arg1	study					469:473	the present study	457:473	the present study	457:473	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	10	54	theme	diseases	1619:1626	arg1	context					1598:1604	the context	1594:1604	the context of metabolic diseases	1594:1626	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	0	55	theme	preventive	140:149	arg1	strategy					151:158	a preventive strategy	138:158	a preventive strategy based on prebiotics	138:178	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	3	56	theme	Wistar	621:626	arg1	dams					628:631	Wistar dams	621:631	Wistar dams	621:631	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	4	57	theme	prebiotic	726:734	arg1	inulin					736:741	the prebiotic inulin	722:741	the prebiotic inulin	722:741	We also tested a preventive strategy based on treatment with the prebiotic inulin.					
36510012	5	58	theme	standard	863:870	arg1	diet					872:875	a standard diet	861:875	a standard diet	861:875	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	5	58	theme	standard	863:870	arg1	HFD					880:882	a HFD	878:882	a HFD alone	878:888	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	5	58	theme	standard	863:870	arg1	CPF					891:893	CPF	891:893	CPF	891:893	METHODS From 4 months before gestation to the end of the lactation period, six groups of dams were exposed to either a standard diet, a HFD alone, CPF alone, a combination of a HFD and CPF, and/or inulin supplementation.					
36510012	3	59	theme	microbial	596:604	arg1	populations					606:616	microbial populations	596:616	microbial populations	596:616	The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.					
36510012	10	60	from	interactions	1511:1522	arg1	life					1575:1578	early life	1569:1578	early life	1569:1578	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	8	61	from	dysmetabolism	1257:1269	arg1	flora					1299:1303	the gut flora	1291:1303	the gut flora	1291:1303	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	7	62	theme	metabolite	1146:1155	arg1	production					1157:1166	metabolite production	1146:1166	metabolite production	1146:1166	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36510012	8	63	theme	gut	1295:1297	arg1	flora					1299:1303	the gut flora	1291:1303	the gut flora	1291:1303	RESULTS HFD exposure and CPF + HFD co-exposure induced dysmetabolism and an imbalance in the gut flora in both the dams and the female offspring.					
36510012	10	64	theme	environmental	1532:1544	arg1	pollutants					1546:1555	environmental pollutants	1532:1555	environmental pollutants	1532:1555	CONCLUSION Our results provide a better understanding of the complex interactions between environmental pollutants and diet in early life, including in the context of metabolic diseases.					
36510012	1	65	theme	perinatal	218:226	arg1	period					228:233	the perinatal period	214:233	the perinatal period	214:233	PURPOSE Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota.					
36510012	0	66	theme	diet	56:59	arg1	combination					30:40	a combination	28:40	a combination of a high-fat diet and pesticide	28:73	Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.					
36510012	7	67	theme	lipid	1098:1102	arg1	profile					1104:1110	the lipid profile	1094:1110	the lipid profile	1094:1110	We measured the impacts of these exposures on glycemia, the lipid profile, and the microbiota (composition, metabolite production, and translocation into tissues).					
36580792	0	0	theme	new	88:90	arg1	fat					92:94	a new fat substitute	86:105	a new fat substitute	86:105	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	4	1	from	incorporation	552:564	arg1	sausages					591:598	sausages	591:598	sausages	591:598	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	6	2	theme	meat	1233:1236	arg1	products					1238:1245	meat products	1233:1245	meat products with the desirable characteristics	1233:1280	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	2	3	theme	sausages	449:456	arg1	quality					438:444	the quality	434:444	the quality of sausages	434:456	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	5	4	theme	fat	1066:1068	arg1	P < 0.05					1081:1088	P < 0.05	1081:1088	P < 0.05	1081:1088	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	5	4	theme	fat	1066:1068	arg1	oxidation					1070:1078	fat oxidation	1066:1078	fat oxidation (P < 0.05)	1066:1089	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	3	5	theme	meat	475:478	arg1	pastes					480:485	All meat pastes	471:485	All meat pastes	471:485	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	5	6	theme	sensory	907:913	arg1	acceptability					915:927	a similar overall sensory acceptability	889:927	a similar overall sensory acceptability	889:927	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	4	7	dep	properties	622:631	arg1	cohesiveness					668:679	cohesiveness	668:679	cohesiveness	668:679	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	7	dep	properties	622:631	arg1	hardness					634:641	hardness	634:641	hardness	634:641	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	7	dep	properties	622:631	arg1	springiness					644:654	springiness	644:654	springiness	644:654	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	7	dep	properties	622:631	arg1	resilience					685:694	resilience	685:694	resilience	685:694	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	7	dep	properties	622:631	arg1	properties					622:631	the textural properties	609:631	the textural properties (hardness, springiness, chewiness, cohesiveness and resilience)	609:695	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	7	dep	properties	622:631	arg1	chewiness					657:665	chewiness	657:665	chewiness	657:665	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	8	theme	cooking	778:784	arg1	content					801:807	the cooking loss and TBARS content	774:807	the cooking loss and TBARS content	774:807	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	3	9	theme	gel-like	506:513	arg1	"					544:544	G' > G"	538:544	G' > G"	538:544	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	9	theme	gel-like	506:513	arg1	character					527:535	a strong gel-like rheological character	497:535	a strong gel-like rheological character (G' > G")	497:545	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	10	theme	G	538:538	arg1	"					544:544	G' > G"	538:544	G' > G"	538:544	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	10	theme	G	538:538	arg1	character					527:535	a strong gel-like rheological character	497:535	a strong gel-like rheological character (G' > G")	497:545	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	5	11	theme	similar	891:897	arg1	acceptability					915:927	a similar overall sensory acceptability	889:927	a similar overall sensory acceptability	889:927	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	3	12	theme	rheological	515:525	arg1	"					544:544	G' > G"	538:544	G' > G"	538:544	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	12	theme	rheological	515:525	arg1	character					527:535	a strong gel-like rheological character	497:535	a strong gel-like rheological character (G' > G")	497:545	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	5	13	theme	backfat	845:851	arg1	ratio					866:870	a backfat substitution ratio	843:870	a backfat substitution ratio of 100%	843:878	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	5	14	theme	%	878:878	arg1	ratio					866:870	a backfat substitution ratio	843:870	a backfat substitution ratio of 100%	843:878	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	5	15	theme	overall	899:905	arg1	acceptability					915:927	a similar overall sensory acceptability	889:927	a similar overall sensory acceptability	889:927	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	4	16	theme	textural	613:620	arg1	springiness					644:654	springiness	644:654	springiness	644:654	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	16	theme	textural	613:620	arg1	resilience					685:694	resilience	685:694	resilience	685:694	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	16	theme	textural	613:620	arg1	properties					622:631	the textural properties	609:631	the textural properties (hardness, springiness, chewiness, cohesiveness and resilience)	609:695	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	16	theme	textural	613:620	arg1	hardness					634:641	hardness	634:641	hardness	634:641	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	16	theme	textural	613:620	arg1	chewiness					657:665	chewiness	657:665	chewiness	657:665	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	17	theme	loss	786:789	arg1	content					801:807	the cooking loss and TBARS content	774:807	the cooking loss and TBARS content	774:807	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	0	18	dep	fat	92:94	arg1	substitute					96:105	substitute	96:105	substitute	96:105	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	2	19	theme	volume	350:355	arg1	fraction					357:364	75% corn oil volume fraction	337:364	75% corn oil volume fraction	337:364	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	19	theme	volume	350:355	arg1	emulsion					327:334	Pickering emulsion	317:334	Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles	317:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	20	dep	backfat	304:310	arg1	%					297:297	%	297:297	%	297:297	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	21	theme	oil	346:348	arg1	fraction					357:364	75% corn oil volume fraction	337:364	75% corn oil volume fraction	337:364	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	21	theme	oil	346:348	arg1	emulsion					327:334	Pickering emulsion	317:334	Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles	317:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	0	22	theme	Pickering	0:8	arg1	emulsion					10:17	Pickering emulsion	0:17	Pickering emulsion	0:17	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	4	23	theme	TBARS	795:799	arg1	content					801:807	the cooking loss and TBARS content	774:807	the cooking loss and TBARS content	774:807	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	2	24	theme	-100	293:296	arg1	%					292:292	%	292:292	%	292:292	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	25	theme	corn	341:344	arg1	fraction					357:364	75% corn oil volume fraction	337:364	75% corn oil volume fraction	337:364	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	25	theme	corn	341:344	arg1	emulsion					327:334	Pickering emulsion	317:334	Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles	317:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	26	theme	protein-chitosan	394:409	arg1	particles					421:429	modified pea protein-chitosan composite particles	381:429	modified pea protein-chitosan composite particles	381:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	6	27	theme	modified	1149:1156	arg1	particles					1189:1197	modified pea protein-chitosan composite particles	1149:1197	modified pea protein-chitosan composite particles	1149:1197	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	6	28	with	products	1238:1245	arg1	characteristics					1266:1280	the desirable characteristics	1252:1280	the desirable characteristics	1252:1280	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	1	29	theme	animal	195:200	arg1	fat					202:204	animal fat	195:204	animal fat due to high stability and solid-like properties	195:252	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36580792	2	30	theme	pea	390:392	arg1	particles					421:429	modified pea protein-chitosan composite particles	381:429	modified pea protein-chitosan composite particles	381:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	31	theme	composite	411:419	arg1	particles					421:429	modified pea protein-chitosan composite particles	381:429	modified pea protein-chitosan composite particles	381:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	5	32	theme	texture	995:1001	arg1	properties					1003:1012	texture properties	995:1012	texture properties	995:1012	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	2	33	theme	25	290:291	arg1	%					292:292	%	292:292	%	292:292	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	4	34	theme	emulsion	579:586	arg1	incorporation					552:564	The incorporation	548:564	The incorporation of Pickering emulsion in sausages	548:598	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	0	35	theme	pea	42:44	arg1	particles					73:81	modified pea protein-chitosan composite particles	33:81	modified pea protein-chitosan composite particles	33:81	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	0	36	theme	sausages	136:143	arg1	quality					120:126	the quality	116:126	the quality of pork sausages	116:143	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	6	37	theme	composite	1179:1187	arg1	particles					1189:1197	modified pea protein-chitosan composite particles	1149:1197	modified pea protein-chitosan composite particles	1149:1197	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	0	38	theme	modified	33:40	arg1	particles					73:81	modified pea protein-chitosan composite particles	33:81	modified pea protein-chitosan composite particles	33:81	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	0	39	theme	pork	131:134	arg1	sausages					136:143	pork sausages	131:143	pork sausages	131:143	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	6	40	theme	protein-chitosan	1162:1177	arg1	particles					1189:1197	modified pea protein-chitosan composite particles	1149:1197	modified pea protein-chitosan composite particles	1149:1197	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	0	41	theme	composite	63:71	arg1	particles					73:81	modified pea protein-chitosan composite particles	33:81	modified pea protein-chitosan composite particles	33:81	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	6	42	theme	desirable	1256:1264	arg1	characteristics					1266:1280	the desirable characteristics	1252:1280	the desirable characteristics	1252:1280	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	3	43	theme	 > G	540:543	arg1	"					544:544	G' > G"	538:544	G' > G"	538:544	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	43	theme	 > G	540:543	arg1	character					527:535	a strong gel-like rheological character	497:535	a strong gel-like rheological character (G' > G")	497:545	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	2	44	theme	Pickering	317:325	arg1	fraction					357:364	75% corn oil volume fraction	337:364	75% corn oil volume fraction	337:364	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	44	theme	Pickering	317:325	arg1	emulsion					327:334	Pickering emulsion	317:334	Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles	317:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	0	45	theme	protein-chitosan	46:61	arg1	particles					73:81	modified pea protein-chitosan composite particles	33:81	modified pea protein-chitosan composite particles	33:81	Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages.					
36580792	6	46	dep	fat	1214:1216	arg1	substitute					1218:1227	substitute	1218:1227	substitute for meat products with the desirable characteristics	1218:1280	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	5	47	theme	best	966:969	arg1	properties					983:992	the best rheological properties	962:992	the best rheological properties	962:992	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	1	48	dep	potential	170:178	arg1	substitute					180:189	substitute	180:189	substitute for animal fat due to high stability and solid-like properties	180:252	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36580792	5	49	theme	substitution	853:864	arg1	ratio					866:870	a backfat substitution ratio	843:870	a backfat substitution ratio of 100%	843:878	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	2	50	from	effect	270:275	arg1	quality					438:444	the quality	434:444	the quality of sausages	434:456	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	6	51	theme	Pickering	1116:1124	arg1	emulsion					1126:1133	Pickering emulsion	1116:1133	Pickering emulsion stabilized by modified pea protein-chitosan composite particles	1116:1197	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	6	51	theme	Pickering	1116:1124	arg1	fat					1214:1216	fat	1214:1216	fat	1214:1216	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	4	52	dep	uniformity	705:714	arg1	the					701:703	the	701:703	the	701:703	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	5	53	theme	rheological	971:981	arg1	properties					983:992	the best rheological properties	962:992	the best rheological properties	962:992	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	2	54	dep	%	297:297	arg1	%					292:292	%	292:292	%	292:292	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	1	55	theme	high	213:216	arg1	stability					218:226	high stability	213:226	high stability	213:226	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36580792	3	56	theme	strong	499:504	arg1	"					544:544	G' > G"	538:544	G' > G"	538:544	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	3	56	theme	strong	499:504	arg1	character					527:535	a strong gel-like rheological character	497:535	a strong gel-like rheological character (G' > G")	497:545	All meat pastes exhibited a strong gel-like rheological character (G' > G").					
36580792	6	57	theme	pea	1158:1160	arg1	particles					1189:1197	modified pea protein-chitosan composite particles	1149:1197	modified pea protein-chitosan composite particles	1149:1197	The results showed that Pickering emulsion stabilized by modified pea protein-chitosan composite particles is a potential fat substitute for meat products with the desirable characteristics.					
36580792	4	58	theme	micromorphology	735:749	arg1	uniformity					705:714	uniformity	705:714	uniformity	705:714	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	hardness					634:641	hardness	634:641	hardness	634:641	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	compactness					720:730	compactness	720:730	compactness	720:730	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	springiness					644:654	springiness	644:654	springiness	644:654	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	resilience					685:694	resilience	685:694	resilience	685:694	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	properties					622:631	the textural properties	609:631	the textural properties (hardness, springiness, chewiness, cohesiveness and resilience)	609:695	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	4	58	theme	micromorphology	735:749	arg1	chewiness					657:665	chewiness	657:665	chewiness	657:665	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	2	59	theme	pork	299:302	arg1	backfat					304:310	25%-100% pork backfat	290:310	25%-100% pork backfat	290:310	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	5	60	with	sausages	829:836	arg1	ratio					866:870	a backfat substitution ratio	843:870	a backfat substitution ratio of 100%	843:878	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	2	61	theme	modified	381:388	arg1	particles					421:429	modified pea protein-chitosan composite particles	381:429	modified pea protein-chitosan composite particles	381:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	62	theme	%	339:339	arg1	fraction					357:364	75% corn oil volume fraction	337:364	75% corn oil volume fraction	337:364	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	2	62	theme	%	339:339	arg1	emulsion					327:334	Pickering emulsion	317:334	Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles	317:429	Therefore, the effect of replacing 25%-100% pork backfat with Pickering emulsion (75% corn oil volume fraction) stabilized by modified pea protein-chitosan composite particles on the quality of sausages was studied.					
36580792	4	63	theme	Pickering	569:577	arg1	emulsion					579:586	Pickering emulsion	569:586	Pickering emulsion	569:586	The incorporation of Pickering emulsion in sausages enhanced the textural properties (hardness, springiness, chewiness, cohesiveness and resilience) and the uniformity and compactness of micromorphology, as well as suppressed the cooking loss and TBARS content.					
36580792	5	64	theme	backfat	936:942	arg1	sausage					944:950	the backfat sausage	932:950	the backfat sausage	932:950	In particular, the sausages with a backfat substitution ratio of 100%, showing a similar overall sensory acceptability to the backfat sausage, revealed the best rheological properties, texture properties and micromorphology and the lowest cooking loss and fat oxidation (P < 0.05).					
36580792	1	65	theme	Pickering	146:154	arg1	emulsion					156:163	Pickering emulsion	146:163	Pickering emulsion	146:163	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36580792	1	65	theme	Pickering	146:154	arg1	potential					170:178	a potential	168:178	a potential substitute for animal fat due to high stability and solid-like properties	168:252	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36580792	1	66	theme	solid-like	232:241	arg1	properties					243:252	solid-like properties	232:252	solid-like properties	232:252	Pickering emulsion is a potential substitute for animal fat due to high stability and solid-like properties.					
36581036	0	0	theme	ovotransferrin	71:84	arg1	films					109:113	ovotransferrin and chitosan composite films	71:113	ovotransferrin and chitosan composite films	71:113	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	7	1	theme	tensile	1244:1250	arg1	strength					1252:1259	The tensile strength	1240:1259	The tensile strength of the film	1240:1271	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	6	2	from	improvement	1194:1204	arg1	performance					1214:1224	film performance	1209:1224	film performance	1209:1224	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	2	3	dep	Fourier	495:501	arg1	transform					503:511	transform	503:511	transform infrared spectroscopy	503:533	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	1	4	theme	composite	318:326	arg1	films					328:332	the composite films	314:332	the composite films	314:332	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	4	5	theme	pure	914:917	arg1	film					919:922	the pure film	910:922	the pure film	910:922	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	1	6	theme	OVT/CS	156:161	arg1	films					174:178	ovotransferrin/chitosan (OVT/CS) composite films	131:178	ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA)	131:211	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	0	7	theme	chitosan	90:97	arg1	films					109:113	ovotransferrin and chitosan composite films	71:113	ovotransferrin and chitosan composite films	71:113	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	0	8	from	Effects	0:6	arg1	properties					57:66	properties	57:66	properties	57:66	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	0	8	from	Effects	0:6	arg1	structure					43:51	structure	43:51	structure	43:51	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	6	9	dep	%	1120:1120	arg1	W/W					1123:1125	W/W	1123:1125	W/W	1123:1125	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	6	10	theme	significant	1182:1192	arg1	improvement					1194:1204	the most significant improvement	1173:1204	the most significant improvement in film performance	1173:1224	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	5	11	theme	water	1011:1015	arg1	resistance					1017:1026	water resistance	1011:1026	water resistance	1011:1026	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	2	12	theme	infrared	513:520	arg1	spectroscopy					522:533	infrared spectroscopy	513:533	infrared spectroscopy	513:533	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	8	13	with	CS	1449:1450	arg1	CA					1457:1458	CA	1457:1458	CA	1457:1458	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	0	14	theme	films	109:113	arg1	properties					57:66	properties	57:66	properties	57:66	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	0	14	theme	films	109:113	arg1	structure					43:51	structure	43:51	structure	43:51	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	4	15	theme	film	900:903	arg1	activity					874:881	a significantly higher antibacterial activity	837:881	a significantly higher antibacterial activity of the composite film than the pure film	837:922	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	6	16	from	W/W	1123:1125	arg1	basis					1137:1141	a dry basis	1131:1141	a dry basis of the weight of OVT and CS	1131:1169	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	7	17	theme	swelling	1341:1348	arg1	degree					1350:1355	the swelling degree	1337:1355	the swelling degree	1337:1355	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	0	18	theme	composite	99:107	arg1	films					109:113	ovotransferrin and chitosan composite films	71:113	ovotransferrin and chitosan composite films	71:113	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	1	19	dep	structure	270:278	arg1	the					266:268	the	266:268	the	266:268	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	4	20	theme	composite	890:898	arg1	film					900:903	the composite film	886:903	the composite film	886:903	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	5	21	theme	cross-linked	1035:1046	arg1	films					1048:1052	the cross-linked films	1031:1052	the cross-linked films	1031:1052	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	8	22	theme	observed	1395:1402	arg1	phenomena					1404:1412	The observed phenomena	1391:1412	The observed phenomena	1391:1412	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	1	23	theme	composite	164:172	arg1	films					174:178	ovotransferrin/chitosan (OVT/CS) composite films	131:178	ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA)	131:211	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	5	24	theme	barrier	988:994	arg1	properties					996:1005	barrier properties	988:1005	barrier properties	988:1005	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	2	25	theme	electrostatic	574:586	arg1	interactions					588:599	electrostatic interactions	574:599	electrostatic interactions	574:599	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	3	26	theme	microscope	715:724	arg1	images					726:731	Scanning electron microscope images	697:731	Scanning electron microscope images	697:731	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	3	27	theme	electron	706:713	arg1	images					726:731	Scanning electron microscope images	697:731	Scanning electron microscope images	697:731	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	1	28	theme	CA	246:247	arg1	cross-linking					249:261	CA cross-linking	246:261	CA cross-linking	246:261	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	8	29	theme	edible	1482:1487	arg1	films					1489:1493	functional edible films	1471:1493	functional edible films	1471:1493	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	6	30	theme	CS	1168:1169	arg1	weight					1150:1155	the weight	1146:1155	the weight of OVT and CS	1146:1169	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	2	31	theme	cross-linking	357:369	arg1	degree					371:376	The cross-linking degree	353:376	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method	353:437	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	0	32	theme	acid	18:21	arg1	crosslinking					23:34	citric acid crosslinking	11:34	citric acid crosslinking	11:34	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	1	33	theme	cross-linking	249:261	arg1	effects					235:241	the effects	231:241	the effects of CA cross-linking on the structure and physicochemical properties of the composite films	231:332	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	2	34	theme	hydrogen	555:562	arg1	bonds					564:568	more hydrogen bonds	550:568	more hydrogen bonds	550:568	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	8	35	theme	improved	1500:1507	arg1	properties					1509:1518	improved properties	1500:1518	improved properties	1500:1518	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	0	36	theme	citric	11:16	arg1	crosslinking					23:34	citric acid crosslinking	11:34	citric acid crosslinking	11:34	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	2	37	theme	more	550:553	arg1	bonds					564:568	more hydrogen bonds	550:568	more hydrogen bonds	550:568	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	4	38	theme	synergistic	784:794	arg1	inhibition					796:805	The synergistic inhibition	780:805	The synergistic inhibition between the matrix	780:824	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	1	39	theme	citric	196:201	arg1	CA					209:210	CA	209:210	CA	209:210	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	1	39	theme	citric	196:201	arg1	acid					203:206	citric acid	196:206	citric acid (CA)	196:211	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	6	40	theme	weight	1150:1155	arg1	basis					1137:1141	a dry basis	1131:1141	a dry basis of the weight of OVT and CS	1131:1169	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	6	41	theme	CA	1109:1110	arg1	%					1120:1120	5 wt%	1116:1120	5 wt% (W/W, on a dry basis of the weight of OVT and CS)	1116:1170	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	6	41	theme	CA	1109:1110	arg1	concentration					1092:1104	the concentration	1088:1104	the concentration of CA	1088:1110	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	0	42	dep	structure	43:51	arg1	the					39:41	the	39:41	the	39:41	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	2	43	theme	acid	420:423	arg1	method					432:437	2,4,6-trinitrobenzenesulfonic acid (TNBS) method	390:437	2,4,6-trinitrobenzenesulfonic acid (TNBS) method	390:437	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	0	44	theme	crosslinking	23:34	arg1	Effects					0:6	Effects	0:6	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.	0:114	Effects of citric acid crosslinking on the structure and properties of ovotransferrin and chitosan composite films.					
36581036	5	45	link	uncross-linked	939:952	arg1	films					954:958	uncross-linked films	939:958	uncross-linked films	939:958	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	3	46	theme	Differential	640:651	arg1	calorimetry					662:672	Differential scanning calorimetry	640:672	Differential scanning calorimetry	640:672	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	4	47	theme	antibacterial	860:872	arg1	activity					874:881	a significantly higher antibacterial activity	837:881	a significantly higher antibacterial activity of the composite film than the pure film	837:922	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	2	48	theme	2,4,6-trinitrobenzenesulfonic	390:418	arg1	acid					420:423	2,4,6-trinitrobenzenesulfonic acid	390:423	2,4,6-trinitrobenzenesulfonic acid (TNBS) method	390:437	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	2	48	theme	2,4,6-trinitrobenzenesulfonic	390:418	arg1	TNBS					426:429	TNBS	426:429	TNBS	426:429	The cross-linking degree measured by 2,4,6-trinitrobenzenesulfonic acid (TNBS) method confirmed that CA was cross-linked with the matrix, and Fourier transform infrared spectroscopy confirmed that more hydrogen bonds and electrostatic interactions were formed between CA and the matrix.					
36581036	8	49	with	cross-linking	1427:1439	arg1	CA					1457:1458	CA	1457:1458	CA	1457:1458	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	7	50	theme	51.5 	1372:1376	arg1	%					1377:1377	%	1377:1377	%	1377:1377	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	3	51	theme	scanning	653:660	arg1	calorimetry					662:672	Differential scanning calorimetry	640:672	Differential scanning calorimetry	640:672	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	7	52	dep	%	1377:1377	arg1	to					1379:1380	to	1379:1380	to	1379:1380	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	1	53	theme	films	328:332	arg1	structure					270:278	structure	270:278	structure	270:278	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	1	53	theme	films	328:332	arg1	properties					300:309	physicochemical properties	284:309	physicochemical properties	284:309	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	1	54	theme	physicochemical	284:298	arg1	properties					300:309	physicochemical properties	284:309	physicochemical properties	284:309	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	1	55	from	effects	235:241	arg1	structure					270:278	structure	270:278	structure	270:278	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	1	55	from	effects	235:241	arg1	properties					300:309	physicochemical properties	284:309	physicochemical properties	284:309	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	8	56	theme	functional	1471:1480	arg1	films					1489:1493	functional edible films	1471:1493	functional edible films	1471:1493	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	7	57	theme	24.23 	1382:1387	arg1	%					1377:1377	%	1377:1377	%	1377:1377	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	5	58	theme	mechanical	965:974	arg1	properties					976:985	the mechanical properties	961:985	the mechanical properties	961:985	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	3	59	theme	Scanning	697:704	arg1	images					726:731	Scanning electron microscope images	697:731	Scanning electron microscope images	697:731	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	5	60	theme	films	1048:1052	arg1	properties					976:985	the mechanical properties	961:985	the mechanical properties	961:985	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	5	60	theme	films	1048:1052	arg1	properties					996:1005	barrier properties	988:1005	barrier properties	988:1005	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	5	60	theme	films	1048:1052	arg1	resistance					1017:1026	water resistance	1011:1026	water resistance	1011:1026	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	7	61	theme	film	1268:1271	arg1	strength					1252:1259	The tensile strength	1240:1259	The tensile strength of the film	1240:1271	The tensile strength of the film increased from 32.05 MPa without cross-linking to 61.99 MPa and the swelling degree decreased from 51.5 % to 24.23 %.					
36581036	3	62	theme	X-ray	675:679	arg1	diffraction					681:691	X-ray diffraction	675:691	X-ray diffraction	675:691	Differential scanning calorimetry, X-ray diffraction and Scanning electron microscope images revealed the compatibility between substances.					
36581036	6	63	theme	film	1209:1212	arg1	performance					1214:1224	film performance	1209:1224	film performance	1209:1224	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	5	64	theme	uncross-linked	939:952	arg1	films					954:958	uncross-linked films	939:958	uncross-linked films	939:958	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36581036	8	65	dep	cross-linking	1427:1439	arg1	OVT					1441:1443	OVT	1441:1443	OVT	1441:1443	The observed phenomena suggest that cross-linking OVT and CS with CA can obtain functional edible films with improved properties.					
36581036	6	66	theme	dry	1133:1135	arg1	basis					1137:1141	a dry basis	1131:1141	a dry basis of the weight of OVT and CS	1131:1169	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	4	67	theme	higher	853:858	arg1	activity					874:881	a significantly higher antibacterial activity	837:881	a significantly higher antibacterial activity of the composite film than the pure film	837:922	The synergistic inhibition between the matrix results in a significantly higher antibacterial activity of the composite film than the pure film.					
36581036	6	68	theme	OVT	1160:1162	arg1	weight					1150:1155	the weight	1146:1155	the weight of OVT and CS	1146:1169	When the concentration of CA was 5 wt% (W/W, on a dry basis of the weight of OVT and CS), the most significant improvement in film performance was obtained.					
36581036	1	69	theme	ovotransferrin/chitosan	131:153	arg1	films					174:178	ovotransferrin/chitosan (OVT/CS) composite films	131:178	ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA)	131:211	In this study, ovotransferrin/chitosan (OVT/CS) composite films cross-linked by citric acid (CA) were prepared and the effects of CA cross-linking on the structure and physicochemical properties of the composite films were investigated.					
36581036	5	70	link	cross-linked	1035:1046	arg1	films					1048:1052	the cross-linked films	1031:1052	the cross-linked films	1031:1052	Compared with uncross-linked films, the mechanical properties, barrier properties and water resistance of the cross-linked films were significantly improved.					
36055609	6	0	theme	stiffness	1023:1031	arg1	chitin					988:993	chitin	988:993	chitin	988:993	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	6	0	theme	stiffness	1023:1031	arg1	component					1010:1018	the primary component	998:1018	the primary component of stiffness	998:1031	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	3	1	theme	new	469:471	arg1	approach					525:532	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach	467:532	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	14	2	theme	tracheal	2427:2434	arg1	taenidia					2436:2443	unfixed tracheal taenidia	2419:2443	unfixed tracheal taenidia	2419:2443	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	9	3	theme	taenidia	1595:1602	arg1	fibres					1604:1609	taenidia fibres	1595:1609	taenidia fibres	1595:1609	Based on our results, we propose that the distinct moduli of taenidia fibres indicate sophisticated evolution with elasticity playing a key role in optimization.					
36055609	6	4	theme	mechanical	1123:1132	arg1	properties					1134:1143	the mechanical properties	1119:1143	the mechanical properties of single taenidia fibres (38% of total data)	1119:1189	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	12	5	theme	interior	2145:2152	arg1	canal					2163:2167	the interior acoustic canal	2141:2167	the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2141:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	10	6	theme	SIGNIFICANCE	1709:1720	arg1	STATEMENT					1696:1704	STATEMENT	1696:1704	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.	1696:1876	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	6	7	theme	data	1185:1188	arg1	data					1185:1188	total data	1179:1188	total data	1179:1188	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	6	7	theme	data	1185:1188	arg1	%					1174:1174	38%	1172:1174	38% of total data	1172:1188	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	3	8	theme	Force	497:501	arg1	Spectroscopy					503:514	Atomic Force Microscopy Force Spectroscopy	473:514	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	3	8	theme	Force	497:501	arg1	AFM-FS					517:522	AFM-FS	517:522	AFM-FS	517:522	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	12	9	theme	nanometre	2081:2089	arg1	level					2091:2095	the nanometre level	2077:2095	the nanometre level	2077:2095	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	12	10	from	canal	2163:2167	arg1	research					2235:2242	hearing research	2227:2242	hearing research	2227:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	5	11	theme	contact	848:854	arg1	model					856:860	the Hertzian contact model	835:860	the Hertzian contact model	835:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	11	12	theme	reinforcement	1996:2008	arg1	micro-fibres					1921:1932	spiral cuticular micro-fibres	1904:1932	spiral cuticular micro-fibres	1904:1932	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	11	12	theme	reinforcement	1996:2008	arg1	elements					1973:1980	the primary elements	1961:1980	the primary elements of mechanical reinforcement	1961:2008	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	13	13	theme	Taenidia	2245:2252	arg1	fibres					2254:2259	Taenidia fibres	2245:2259	Taenidia fibres	2245:2259	Taenidia fibres were immobilized on a hard substrate and the indenter directly approached the epicuticle surface.					
36055609	4	14	theme	Mechanical	611:620	arg1	properties					622:631	Mechanical properties	611:631	Mechanical properties	611:631	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	1	15	from	environment	255:265	arg1	sounds					230:235	sounds	230:235	sounds from the external environment	230:265	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	10	16	theme	foreleg	1758:1764	arg1	tracheae					1766:1773	the foreleg tracheae	1754:1773	the foreleg tracheae	1754:1773	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	7	17	theme	structural	1285:1294	arg1	optimization					1296:1307	structural optimization	1285:1307	structural optimization between compliance and rigidity	1285:1339	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	4	18	theme	taenidia	686:693	arg1	axis					669:672	the longitudinal axis	652:672	the longitudinal axis of hydrated taenidia	652:693	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	5	19	theme	GPa	974:976	arg1	mean					938:941	a mean	936:941	a mean of 5.2 ± 7 GPa and median 1.03 GPa	936:976	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	11	20	theme	cuticular	1911:1919	arg1	elements					1973:1980	the primary elements	1961:1980	the primary elements of mechanical reinforcement	1961:2008	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	11	20	theme	cuticular	1911:1919	arg1	micro-fibres					1921:1932	spiral cuticular micro-fibres	1904:1932	spiral cuticular micro-fibres	1904:1932	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	6	21	theme	taenidia	1155:1162	arg1	fibres					1164:1169	single taenidia fibres	1148:1169	single taenidia fibres (38% of total data)	1148:1189	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	12	22	theme	AFM-based	2027:2035	arg1	method					2037:2042	an AFM-based method	2024:2042	an AFM-based method to indent individual taenidia	2024:2072	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	5	23	theme	26.5	921:924	arg1	MPa					914:916	MPa	914:916	MPa	914:916	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	3	24	theme	bush-cricket	579:590	arg1	elongata					601:608	the bush-cricket Mecopoda elongata	575:608	the bush-cricket Mecopoda elongata	575:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	5	25	theme	13.9	909:912	arg1	MPa					914:916	MPa	914:916	MPa	914:916	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	14	26	dep	in	2482:2483	arg1	vivo					2485:2488	vivo	2485:2488	vivo	2485:2488	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	4	27	theme	longitudinal	656:667	arg1	axis					669:672	the longitudinal axis	652:672	the longitudinal axis of hydrated taenidia	652:693	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	0	28	theme	Force	71:75	arg1	Microscopy					77:86	Atomic Force Microscopy nanoindentation	64:102	Atomic Force Microscopy nanoindentation	64:102	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	5	29	theme	extension	797:805	arg1	curves					807:812	the force-displacement (F-d) extension curves	768:812	the force-displacement (F-d) extension curves at low strains using the Hertzian contact model	768:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	14	30	theme	structures	2528:2537	arg1	investigations					2501:2514	further in vivo mechanical investigations	2474:2514	further in vivo mechanical investigations of auditory structures	2474:2537	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	12	31	theme	species	2216:2222	arg1	canal					2163:2167	the interior acoustic canal	2141:2167	the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2141:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	5	32	dep	MPa	914:916	arg1	to					918:919	to	918:919	to	918:919	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	5	33	from	Analysis	756:763	arg1	strains					821:827	low strains	817:827	low strains using the Hertzian contact model	817:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	5	34	theme	Elastic	872:878	arg1	modulus					880:886	an Elastic modulus	869:886	an Elastic modulus distribution between 13.9 MPa to 26.5 GPa	869:928	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	12	35	theme	hearing	2227:2233	arg1	research					2235:2242	hearing research	2227:2242	hearing research	2227:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	4	36	theme	hyperbolic	739:748	arg1	tips					750:753	precision hyperbolic tips	729:753	precision hyperbolic tips	729:753	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	14	37	theme	mechanical	2490:2499	arg1	investigations					2501:2514	further in vivo mechanical investigations	2474:2514	further in vivo mechanical investigations of auditory structures	2474:2537	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	12	38	theme	Mecopoda	2189:2196	arg1	species					2216:2222	the bush-cricket Mecopoda elongata, a model species	2172:2222	the bush-cricket Mecopoda elongata, a model species	2172:2222	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	14	39	theme	in	2482:2483	arg1	investigations					2501:2514	further in vivo mechanical investigations	2474:2514	further in vivo mechanical investigations of auditory structures	2474:2537	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	6	40	theme	primary	1002:1008	arg1	chitin					988:993	chitin	988:993	chitin	988:993	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	6	40	theme	primary	1002:1008	arg1	component					1010:1018	the primary component	998:1018	the primary component of stiffness	998:1031	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	8	41	theme	content	1480:1486	arg1	percentage					1447:1456	the percentage	1443:1456	the percentage of resilin and chitin content, their location and structural configuration	1443:1531	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	4	42	theme	single	709:714	arg1	fibres					716:721	single fibres	709:721	single fibres using precision hyperbolic tips	709:753	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	1	43	theme	interior	274:281	arg1	ear					283:285	the interior ear	270:285	the interior ear	270:285	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	7	44	theme	intricate	1226:1234	arg1	response					1251:1258	an intricate chitin-resilin response	1223:1258	an intricate chitin-resilin response	1223:1258	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	2	45	theme	large	408:412	arg1	stresses					414:421	large stresses	408:421	large stresses	408:421	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	12	46	theme	canal	2163:2167	arg1	properties					2127:2136	local mechanical properties	2110:2136	local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2110:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	0	47	theme	bush-cricket	18:29	arg1	mechanics					48:56	bush-cricket acoustic trachea mechanics	18:56	bush-cricket acoustic trachea mechanics	18:56	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	1	48	theme	respiratory	122:132	arg1	tracheae					134:141	the respiratory tracheae	118:141	the respiratory tracheae	118:141	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	12	49	dep	Mecopoda	2189:2196	arg1	elongata					2198:2205	Mecopoda elongata, a model	2189:2214	elongata	2198:2205	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	12	49	dep	Mecopoda	2189:2196	arg1	model					2210:2214	a model	2208:2214	a model	2208:2214	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	12	50	theme	mechanical	2116:2125	arg1	properties					2127:2136	local mechanical properties	2110:2136	local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2110:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	0	51	theme	trachea	40:46	arg1	mechanics					48:56	bush-cricket acoustic trachea mechanics	18:56	bush-cricket acoustic trachea mechanics	18:56	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	14	52	theme	further	2474:2480	arg1	investigations					2501:2514	further in vivo mechanical investigations	2474:2514	further in vivo mechanical investigations of auditory structures	2474:2537	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	8	53	theme	Finite-element	1342:1355	arg1	analysis					1357:1364	Finite-element analysis	1342:1364	Finite-element analysis on composite materials	1342:1387	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	5	54	theme	force-displacement	772:789	arg1	curves					807:812	the force-displacement (F-d) extension curves	768:812	the force-displacement (F-d) extension curves at low strains using the Hertzian contact model	768:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	5	55	dep	force-displacement	772:789	arg1	F-d					792:794	F-d	792:794	F-d	792:794	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	11	56	theme	spiral	1904:1909	arg1	elements					1973:1980	the primary elements	1961:1980	the primary elements of mechanical reinforcement	1961:2008	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	11	56	theme	spiral	1904:1909	arg1	micro-fibres					1921:1932	spiral cuticular micro-fibres	1904:1932	spiral cuticular micro-fibres	1904:1932	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	2	57	theme	ears	315:318	arg1	location					299:306	the location	295:306	the location of the ears in the forelegs	295:334	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	12	58	from	properties	2127:2136	arg1	research					2235:2242	hearing research	2227:2242	hearing research	2227:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	7	59	dep	400	1215:1217	arg1	to					1212:1213	to	1212:1213	to	1212:1213	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	10	60	dep	STATEMENT	1696:1704	arg1	evolved					1780:1786	evolved	1780:1786	have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg	1775:1875	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	3	61	theme	Atomic	473:478	arg1	Spectroscopy					503:514	Atomic Force Microscopy Force Spectroscopy	473:514	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	3	61	theme	Atomic	473:478	arg1	AFM-FS					517:522	AFM-FS	517:522	AFM-FS	517:522	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	13	62	theme	hard	2283:2286	arg1	substrate					2288:2296	a hard substrate	2281:2296	a hard substrate	2281:2296	Taenidia fibres were immobilized on a hard substrate and the indenter directly approached the epicuticle surface.					
36055609	9	63	theme	distinct	1576:1583	arg1	moduli					1585:1590	the distinct moduli	1572:1590	the distinct moduli of taenidia fibres	1572:1609	Based on our results, we propose that the distinct moduli of taenidia fibres indicate sophisticated evolution with elasticity playing a key role in optimization.					
36055609	1	64	theme	external	246:253	arg1	environment					255:265	the external environment	242:265	the external environment	242:265	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	14	65	theme	taenidia	2436:2443	arg1	nano-structure					2401:2414	the nano-structure	2397:2414	the nano-structure of unfixed tracheal taenidia	2397:2443	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	10	66	theme	located	1844:1850	arg1	ears					1839:1842	the ears	1835:1842	the ears located on the tibia of each leg	1835:1875	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	3	67	theme	Spectroscopy	503:514	arg1	approach					525:532	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach	467:532	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	14	68	theme	unfixed	2419:2425	arg1	taenidia					2436:2443	unfixed tracheal taenidia	2419:2443	unfixed tracheal taenidia	2419:2443	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	9	69	theme	fibres	1604:1609	arg1	moduli					1585:1590	the distinct moduli	1572:1590	the distinct moduli of taenidia fibres	1572:1609	Based on our results, we propose that the distinct moduli of taenidia fibres indicate sophisticated evolution with elasticity playing a key role in optimization.					
36055609	10	70	theme	leg	1873:1875	arg1	tibia					1859:1863	the tibia	1855:1863	the tibia of each leg	1855:1875	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	3	71	theme	Microscopy	486:495	arg1	Spectroscopy					503:514	Atomic Force Microscopy Force Spectroscopy	473:514	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	3	71	theme	Microscopy	486:495	arg1	AFM-FS					517:522	AFM-FS	517:522	AFM-FS	517:522	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	1	72	theme	ear	181:183	arg1	tracheae					168:175	bush-crickets' acoustic tracheae	144:175	bush-crickets' acoustic tracheae (or ear canals)	144:191	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	1	72	theme	ear	181:183	arg1	canals					185:190	ear canals	181:190	ear canals	181:190	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	14	73	theme	nano-structure	2401:2414	arg1	This					2359:2362	This	2359:2362	This	2359:2362	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	14	73	theme	nano-structure	2401:2414	arg1	characterization					2377:2392	the first characterization	2367:2392	the first characterization of the nano-structure of unfixed tracheal taenidia	2367:2443	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	9	74	theme	sophisticated	1620:1632	arg1	evolution					1634:1642	sophisticated evolution	1620:1642	sophisticated evolution	1620:1642	Based on our results, we propose that the distinct moduli of taenidia fibres indicate sophisticated evolution with elasticity playing a key role in optimization.					
36055609	6	75	theme	total	1179:1183	arg1	data					1185:1188	total data	1179:1188	total data	1179:1188	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	11	76	theme	primary	1965:1971	arg1	micro-fibres					1921:1932	spiral cuticular micro-fibres	1904:1932	spiral cuticular micro-fibres	1904:1932	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	11	76	theme	primary	1965:1971	arg1	elements					1973:1980	the primary elements	1961:1980	the primary elements of mechanical reinforcement	1961:2008	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	5	77	theme	Hertzian	839:846	arg1	model					856:860	the Hertzian contact model	835:860	the Hertzian contact model	835:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	13	78	theme	epicuticle	2339:2348	arg1	surface					2350:2356	the epicuticle surface	2335:2356	the epicuticle surface	2335:2356	Taenidia fibres were immobilized on a hard substrate and the indenter directly approached the epicuticle surface.					
36055609	1	79	theme	hollow	197:202	arg1	tubes					204:208	hollow tubes	197:208	hollow tubes evolved to transmit sounds from the external environment to the interior ear	197:285	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	1	79	theme	hollow	197:202	arg1	tracheae					168:175	bush-crickets' acoustic tracheae	144:175	bush-crickets' acoustic tracheae (or ear canals)	144:191	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	8	80	from	analysis	1357:1364	arg1	materials					1379:1387	composite materials	1369:1387	composite materials	1369:1387	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	5	81	theme	low	817:819	arg1	strains					821:827	low strains	817:827	low strains using the Hertzian contact model	817:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	9	82	theme	key	1670:1672	arg1	role					1674:1677	a key role	1668:1677	a key role	1668:1677	Based on our results, we propose that the distinct moduli of taenidia fibres indicate sophisticated evolution with elasticity playing a key role in optimization.					
36055609	8	83	theme	Elastic	1411:1417	arg1	sensitive					1430:1438	sensitive	1430:1438	sensitive	1430:1438	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	8	83	theme	Elastic	1411:1417	arg1	modulus					1419:1425	the Elastic modulus	1407:1425	the Elastic modulus	1407:1425	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	12	84	theme	indent	2047:2052	arg1	taenidia					2065:2072	indent individual taenidia	2047:2072	indent individual taenidia	2047:2072	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	5	85	from	strains	821:827	arg1	Analysis					756:763	Analysis	756:763	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model	756:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	5	85	from	strains	821:827	arg1	curves					807:812	the force-displacement (F-d) extension curves	768:812	the force-displacement (F-d) extension curves at low strains using the Hertzian contact model	768:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	5	86	theme	modulus	880:886	arg1	distribution					888:899	an Elastic modulus distribution	869:899	an Elastic modulus distribution between 13.9 MPa to 26.5 GPa	869:928	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	6	87	theme	fibres	1164:1169	arg1	properties					1134:1143	the mechanical properties	1119:1143	the mechanical properties of single taenidia fibres (38% of total data)	1119:1189	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	4	88	theme	hydrated	677:684	arg1	taenidia					686:693	hydrated taenidia	677:693	hydrated taenidia	677:693	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	10	89	theme	acoustic	1793:1800	arg1	canals					1802:1807	acoustic canals	1793:1807	acoustic canals	1793:1807	STATEMENT OF SIGNIFICANCE: In crickets and bush-crickets, the foreleg tracheae have evolved into acoustic canals, which transport sound to the ears located on the tibia of each leg.					
36055609	6	90	theme	single	1148:1153	arg1	fibres					1164:1169	single taenidia fibres	1148:1169	single taenidia fibres (38% of total data)	1148:1189	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	12	91	from	research	2235:2242	arg1	properties					2127:2136	local mechanical properties	2110:2136	local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2110:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	3	92	theme	taenidia	563:570	arg1	mechanics					550:558	the mechanics	546:558	the mechanics of taenidia	546:570	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	5	93	theme	curves	807:812	arg1	Analysis					756:763	Analysis	756:763	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model	756:860	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	1	94	theme	acoustic	159:166	arg1	tracheae					168:175	bush-crickets' acoustic tracheae	144:175	bush-crickets' acoustic tracheae (or ear canals)	144:191	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	1	94	theme	acoustic	159:166	arg1	canals					185:190	ear canals	181:190	ear canals	181:190	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	1	94	theme	acoustic	159:166	arg1	tubes					204:208	hollow tubes	197:208	hollow tubes evolved to transmit sounds from the external environment to the interior ear	197:285	Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear.					
36055609	6	95	dep	fibres	1164:1169	arg1	data					1185:1188	total data	1179:1188	total data	1179:1188	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	6	95	dep	fibres	1164:1169	arg1	%					1174:1174	38%	1172:1174	38% of total data	1172:1188	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	14	96	theme	auditory	2519:2526	arg1	structures					2528:2537	auditory structures	2519:2537	auditory structures	2519:2537	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	8	97	theme	resilin	1461:1467	arg1	percentage					1447:1456	the percentage	1443:1456	the percentage of resilin and chitin content, their location and structural configuration	1443:1531	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	2	98	from	location	299:306	arg1	forelegs					327:334	the forelegs	323:334	the forelegs	323:334	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	8	99	theme	chitin	1473:1478	arg1	content					1480:1486	chitin content	1473:1486	chitin content	1473:1486	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	4	100	theme	precision	729:737	arg1	tips					750:753	precision hyperbolic tips	729:753	precision hyperbolic tips	729:753	Mechanical properties were examined over the longitudinal axis of hydrated taenidia, by indenting single fibres using precision hyperbolic tips.					
36055609	7	101	dep	indentations	1196:1207	arg1	nm					1219:1220	nm	1219:1220	nm	1219:1220	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	7	102	theme	chitin-resilin	1236:1249	arg1	response					1251:1258	an intricate chitin-resilin response	1223:1258	an intricate chitin-resilin response	1223:1258	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	12	103	theme	bush-cricket	2176:2187	arg1	species					2216:2222	the bush-cricket Mecopoda elongata, a model species	2172:2222	the bush-cricket Mecopoda elongata, a model species	2172:2222	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	0	104	theme	acoustic	31:38	arg1	mechanics					48:56	bush-cricket acoustic trachea mechanics	18:56	bush-cricket acoustic trachea mechanics	18:56	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	7	105	dep	nm	1219:1220	arg1	400					1215:1217	400	1215:1217	400	1215:1217	For indentations up to 400 nm, an intricate chitin-resilin response was observed, suggesting structural optimization between compliance and rigidity.					
36055609	0	106	dep	Microscopy	77:86	arg1	nanoindentation					88:102	nanoindentation	88:102	Atomic Force Microscopy nanoindentation	64:102	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	8	107	theme	structural	1508:1517	arg1	resilin					1461:1467	resilin	1461:1467	resilin	1461:1467	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	8	107	theme	structural	1508:1517	arg1	configuration					1519:1531	structural configuration	1508:1531	structural configuration	1508:1531	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	12	108	theme	acoustic	2154:2161	arg1	canal					2163:2167	the interior acoustic canal	2141:2167	the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2141:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	2	109	theme	acoustic	341:348	arg1	element					381:387	a structural element	368:387	a structural element that can withstand large stresses during locomotion	368:439	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	2	109	theme	acoustic	341:348	arg1	trachea					350:356	the acoustic trachea	337:356	the acoustic trachea	337:356	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	0	110	theme	mechanics	48:56	arg1	Quantification					0:13	Quantification	0:13	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.	0:103	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	12	111	theme	individual	2054:2063	arg1	taenidia					2065:2072	indent individual taenidia	2047:2072	indent individual taenidia	2047:2072	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	5	112	theme	GPa	954:956	arg1	mean					938:941	a mean	936:941	a mean of 5.2 ± 7 GPa and median 1.03 GPa	936:976	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	3	113	theme	Mecopoda	592:599	arg1	elongata					601:608	the bush-cricket Mecopoda elongata	575:608	the bush-cricket Mecopoda elongata	575:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	12	114	theme	local	2110:2114	arg1	properties					2127:2136	local mechanical properties	2110:2136	local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research	2110:2242	We developed an AFM-based method to indent individual taenidia at the nanometre level, to quantify local mechanical properties of the interior acoustic canal of the bush-cricket Mecopoda elongata, a model species in hearing research.					
36055609	2	115	theme	structural	370:379	arg1	element					381:387	a structural element	368:387	a structural element that can withstand large stresses during locomotion	368:439	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	2	115	theme	structural	370:379	arg1	trachea					350:356	the acoustic trachea	337:356	the acoustic trachea	337:356	Due to the location of the ears in the forelegs, the acoustic trachea serves as a structural element that can withstand large stresses during locomotion.					
36055609	0	116	theme	Atomic	64:69	arg1	Microscopy					77:86	Atomic Force Microscopy nanoindentation	64:102	Atomic Force Microscopy nanoindentation	64:102	Quantification of bush-cricket acoustic trachea mechanics using Atomic Force Microscopy nanoindentation.					
36055609	5	117	theme	median	962:967	arg1	GPa					974:976	median 1.03 GPa	962:976	median 1.03 GPa	962:976	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	11	118	theme	mechanical	1985:1994	arg1	reinforcement					1996:2008	mechanical reinforcement	1985:2008	mechanical reinforcement	1985:2008	Tracheae are held open by spiral cuticular micro-fibres called taenidia, which are the primary elements of mechanical reinforcement.					
36055609	14	119	theme	first	2371:2375	arg1	This					2359:2362	This	2359:2362	This	2359:2362	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	14	119	theme	first	2371:2375	arg1	characterization					2377:2392	the first characterization	2367:2392	the first characterization of the nano-structure of unfixed tracheal taenidia	2367:2443	This is the first characterization of the nano-structure of unfixed tracheal taenidia, and should pave the way for further in vivo mechanical investigations of auditory structures.					
36055609	6	120	theme	elasticity	1047:1056	arg1	variation					1034:1042	variation	1034:1042	variation of elasticity in the nanoscale	1034:1073	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	5	121	theme	±	950:950	arg1	GPa					954:956	5.2 ± 7 GPa	946:956	5.2 ± 7 GPa	946:956	Analysis of the force-displacement (F-d) extension curves at low strains using the Hertzian contact model showed an Elastic modulus distribution between 13.9 MPa to 26.5 GPa, with a mean of 5.2 ± 7 GPa and median 1.03 GPa.					
36055609	8	122	theme	composite	1369:1377	arg1	materials					1379:1387	composite materials	1369:1387	composite materials	1369:1387	Finite-element analysis on composite materials demonstrated that the Elastic modulus is sensitive to the percentage of resilin and chitin content, their location and structural configuration.					
36055609	6	123	from	variation	1034:1042	arg1	nanoscale					1065:1073	nanoscale	1065:1073	nanoscale	1065:1073	Although chitin is the primary component of stiffness, variation of elasticity in the nanoscale suggests that resilin significantly affects the mechanical properties of single taenidia fibres (38% of total data).					
36055609	3	124	theme	Force	480:484	arg1	Spectroscopy					503:514	Atomic Force Microscopy Force Spectroscopy	473:514	a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata	467:608	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36055609	3	124	theme	Force	480:484	arg1	AFM-FS					517:522	AFM-FS	517:522	AFM-FS	517:522	In this study, we report a new Atomic Force Microscopy Force Spectroscopy (AFM-FS) approach to quantify the mechanics of taenidia in the bush-cricket Mecopoda elongata.					
36744448	2	0	theme	snakehead	570:578	arg1	budget					529:534	nitrogen and phosphorus budget	505:534	nitrogen and phosphorus budget	505:534	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	0	theme	snakehead	570:578	arg1	quality					496:502	water quality	490:502	water quality	490:502	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	0	theme	snakehead	570:578	arg1	community					550:558	microbial community	540:558	microbial community	540:558	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	3	1	theme	control	661:667	arg1	C					676:676	C	676:676	C	676:676	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	1	theme	control	661:667	arg1	group					669:673	control group	661:673	control group (C, 20% starch)	661:689	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	8	2	theme	resistant	1485:1493	arg1	starch					1495:1500	resistant starch	1485:1500	resistant starch	1485:1500	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	1	3	theme	carbohydrates	236:248	arg1	use					229:231	the use	225:231	the use of carbohydrates as an energy source	225:268	It is essential to increase the use of carbohydrates as an energy source and improve protein synthesis and utilization to reduce ammonia nitrogen emissions.					
36744448	3	4	theme	replacement	856:866	arg1	group					868:872	full replacement group	851:872	full replacement group (FR, 0% starch)	851:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	4	theme	replacement	856:866	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	4	theme	replacement	856:866	arg1	FR					875:876	FR	875:876	FR	875:876	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	4	5	theme	snakehead	941:949	arg1	fish					951:954	hybrid snakehead fish	934:954	hybrid snakehead fish fed with the FR diet	934:975	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	5	6	theme	tail	1219:1222	arg1	water					1224:1228	tail water	1219:1228	tail water	1219:1228	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	9	7	theme	nutritional	1716:1726	arg1	content					1728:1734	whole fish nutritional content	1705:1734	whole fish nutritional content	1705:1734	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	3	8	dep	%	837:837	arg1	starch					839:844	starch	839:844	5% starch	836:844	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	5	9	dep	increased	1057:1065	arg1	decreased					1152:1160	decreased	1152:1160	decreased the proportion of total nitrogen and total phosphorus in tail water	1152:1228	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	4	10	theme	fat	919:921	arg1	content					923:929	The crude protein and crude fat content	891:929	content	923:929	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	10	11	theme	dietary	1763:1769	arg1	utilization					1795:1805	dietary nitrogen and phosphorus utilization	1763:1805	dietary nitrogen and phosphorus utilization	1763:1805	Resistant starch improves dietary nitrogen and phosphorus utilization.					
36744448	0	12	dep	♀ × Channa	176:185	arg1	♂					193:193	Channa maculata ♀ × Channa argus ♂	160:193	Channa maculata ♀ × Channa argus ♂	160:193	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	3	13	dep	groups	717:722	arg1	group					868:872	full replacement group	851:872	full replacement group (FR, 0% starch)	851:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	group					825:829	high replacement group	808:829	high replacement group (HR, 5% starch)	808:845	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	FR					875:876	FR	875:876	FR	875:876	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	HR					832:833	HR	832:833	HR	832:833	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	group					784:788	medium replacement group	765:788	medium replacement group (MR, 10% starch)	765:805	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	13	dep	groups	717:722	arg1	group					741:745	low replacement group	725:745	low replacement group (LR, 15% starch)	725:762	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	0	14	theme	microbial	119:127	arg1	community					129:137	microbial community	119:137	microbial community	119:137	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	6	15	theme	nitrogen	1243:1250	arg1	rate					1276:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	7	16	theme	group	1430:1434	arg1	P < 0.05					1440:1447	P < 0.05	1440:1447	P < 0.05	1440:1447	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	7	16	theme	group	1430:1434	arg1	FR					1436:1437	group FR	1430:1437	group FR (P < 0.05)	1430:1448	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	2	17	theme	microbial	540:548	arg1	community					550:558	microbial community	540:558	microbial community	540:558	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	3	18	theme	starch	710:715	arg1	group					868:872	full replacement group	851:872	full replacement group (FR, 0% starch)	851:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	18	theme	starch	710:715	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	18	theme	starch	710:715	arg1	group					741:745	low replacement group	725:745	low replacement group (LR, 15% starch)	725:762	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	18	theme	starch	710:715	arg1	group					784:788	medium replacement group	765:788	medium replacement group (MR, 10% starch)	765:805	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	18	theme	starch	710:715	arg1	group					825:829	high replacement group	808:829	high replacement group (HR, 5% starch)	808:845	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	19	theme	medium	765:770	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	19	theme	medium	765:770	arg1	group					784:788	medium replacement group	765:788	medium replacement group (MR, 10% starch)	765:805	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	11	20	theme	bacteria	1897:1904	arg1	source					1842:1847	a carbon source	1833:1847	a carbon source	1833:1847	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	20	theme	bacteria	1897:1904	arg1	starch					1818:1823	Resistant starch	1808:1823	Resistant starch	1808:1823	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	20	theme	bacteria	1897:1904	arg1	colonization					1868:1879	the colonization	1864:1879	the colonization of denitrifying bacteria in water	1864:1913	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	4	21	theme	significant	990:1000	arg1	P < 0.05					1015:1022	P < 0.05	1015:1022	P < 0.05	1015:1022	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	4	21	theme	significant	990:1000	arg1	improvement					1002:1012	the most significant improvement	981:1012	the most significant improvement (P < 0.05)	981:1023	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	8	22	used	used	1560:1563	arg2	nitrogen					1532:1539	nitrogen	1532:1539	nitrogen	1532:1539	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	8	22	used	used	1560:1563	arg2	phosphorus					1545:1554	phosphorus	1545:1554	phosphorus	1545:1554	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	3	23	theme	experimental	600:611	arg1	11.4 ± 0.15 g					619:631	11.4 ± 0.15 g	619:631	11.4 ± 0.15 g	619:631	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	23	theme	experimental	600:611	arg1	fish					613:616	Approximately 1350 experimental fish	581:616	Approximately 1350 experimental fish (11.4 ± 0.15 g)	581:632	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	6	24	theme	emission	1267:1274	arg1	rate					1276:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	5	25	theme	phosphorus	1101:1110	arg1	effectiveness					1071:1083	the effectiveness	1067:1083	the effectiveness of nitrogen and phosphorus utilization	1067:1122	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	3	26	theme	replacement	729:739	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	26	theme	replacement	729:739	arg1	group					741:745	low replacement group	725:745	low replacement group (LR, 15% starch)	725:762	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	2	27	theme	Laminaria	450:458	arg1	japonica					460:467	Laminaria japonica	450:467	Laminaria japonica	450:467	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	3	28	theme	%	754:754	arg1	LR					748:749	LR	748:749	LR	748:749	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	28	theme	%	754:754	arg1	starch					756:761	15% starch	752:761	15% starch	752:761	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	0	29	theme	water	69:73	arg1	quality					75:81	water quality	69:81	water quality	69:81	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	7	30	from	prevalent	1417:1425	arg1	P < 0.05					1440:1447	P < 0.05	1440:1447	P < 0.05	1440:1447	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	7	30	from	prevalent	1417:1425	arg1	FR					1436:1437	group FR	1430:1437	group FR (P < 0.05)	1430:1448	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	2	31	theme	water	490:494	arg1	quality					496:502	water quality	490:502	water quality	490:502	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	11	32	theme	Resistant	1808:1816	arg1	source					1842:1847	a carbon source	1833:1847	a carbon source	1833:1847	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	32	theme	Resistant	1808:1816	arg1	starch					1818:1823	Resistant starch	1808:1823	Resistant starch	1808:1823	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	32	theme	Resistant	1808:1816	arg1	colonization					1868:1879	the colonization	1864:1879	the colonization of denitrifying bacteria in water	1864:1913	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	1	33	theme	ammonia	326:332	arg1	emissions					343:351	ammonia nitrogen emissions	326:351	ammonia nitrogen emissions	326:351	It is essential to increase the use of carbohydrates as an energy source and improve protein synthesis and utilization to reduce ammonia nitrogen emissions.					
36744448	3	34	dep	group	784:788	arg1	starch					799:804	10% starch	795:804	10% starch	795:804	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	34	dep	group	784:788	arg1	MR					791:792	MR	791:792	MR	791:792	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	35	theme	10	795:796	arg1	%					797:797	%	797:797	%	797:797	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	2	36	theme	resistant	421:429	arg1	starch					431:436	resistant starch	421:436	resistant starch (kelp meal, Laminaria japonica) replacing starch	421:485	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	36	theme	resistant	421:429	arg1	meal					444:447	kelp meal	439:447	kelp meal	439:447	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	8	37	dep	enhance	1506:1512	arg1	altering					1607:1614	altering	1607:1614	altering environmental microbial composition	1607:1650	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	8	37	dep	enhance	1506:1512	arg1	lessening					1577:1585	lessening	1577:1585	lessening water pollution	1577:1601	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	2	38	theme	60-day	356:361	arg1	experiment					372:381	A 60-day cultural experiment	354:381	A 60-day cultural experiment	354:381	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	3	39	theme	replacement	813:823	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	39	theme	replacement	813:823	arg1	HR					832:833	HR	832:833	HR	832:833	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	39	theme	replacement	813:823	arg1	group					825:829	high replacement group	808:829	high replacement group (HR, 5% starch)	808:845	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	5	40	dep	nitrogen	1088:1095	arg1	utilization					1112:1122	utilization	1112:1122	utilization	1112:1122	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	6	41	theme	minimum	1235:1241	arg1	nitrogen					1243:1250	minimum nitrogen	1235:1250	minimum nitrogen	1235:1250	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	1	42	theme	energy	256:261	arg1	source					263:268	an energy source	253:268	an energy source	253:268	It is essential to increase the use of carbohydrates as an energy source and improve protein synthesis and utilization to reduce ammonia nitrogen emissions.					
36744448	9	43	theme	whole	1705:1709	arg1	content					1728:1734	whole fish nutritional content	1705:1734	whole fish nutritional content	1705:1734	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	5	44	theme	total	1199:1203	arg1	phosphorus					1205:1214	total phosphorus	1199:1214	total phosphorus	1199:1214	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	0	45	theme	Laminaria	40:48	arg1	starch					32:37	resistant starch	22:37	resistant starch (Laminaria japonica)	22:58	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	45	theme	Laminaria	40:48	arg1	japonica					50:57	Laminaria japonica	40:57	Laminaria japonica	40:57	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	3	46	dep	%	681:681	arg1	starch					683:688	starch	683:688	20% starch	679:688	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	9	47	theme	PRACTITIONER	1653:1664	arg1	POINTS					1666:1671	PRACTITIONER POINTS	1653:1671	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.	1653:1735	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	8	48	with	starch	1473:1478	arg1	starch					1495:1500	resistant starch	1485:1500	resistant starch	1485:1500	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	4	49	theme	crude	913:917	arg1	content					923:929	The crude protein and crude fat content	891:929	content	923:929	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	5	50	theme	resistant	1035:1043	arg1	starch					1045:1050	resistant starch	1035:1050	resistant starch	1035:1050	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	4	51	contain	had	977:979	arg2	improvement					1002:1012	the most significant improvement	981:1012	the most significant improvement (P < 0.05)	981:1023	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	4	51	contain	had	977:979	arg1	protein					901:907	The crude protein and crude fat content	891:929	protein	901:907	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	4	51	contain	had	977:979	arg1	content					923:929	The crude protein and crude fat content	891:929	content	923:929	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	4	51	contain	had	977:979	arg2	P < 0.05					1015:1022	P < 0.05	1015:1022	P < 0.05	1015:1022	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	0	52	from	budget	108:113	arg1	♀ × Channa					176:185	♀ × Channa	176:185	♀ × Channa	176:185	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	52	from	budget	108:113	arg1	snakehead					149:157	hybrid snakehead	142:157	hybrid snakehead (Channa maculata ♀ × Channa argus ♂)	142:194	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	5	53	theme	nitrogen	1186:1193	arg1	proportion					1166:1175	the proportion	1162:1175	the proportion of total nitrogen and total phosphorus in tail water	1162:1228	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	8	54	theme	replacing	1463:1471	arg1	starch					1473:1478	replacing starch	1463:1478	replacing starch with resistant starch	1463:1500	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	2	55	theme	hybrid	563:568	arg1	snakehead					570:578	hybrid snakehead	563:578	hybrid snakehead	563:578	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	3	56	dep	%	880:880	arg1	starch					882:887	starch	882:887	0% starch	879:887	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	57	theme	full	851:854	arg1	group					868:872	full replacement group	851:872	full replacement group (FR, 0% starch)	851:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	57	theme	full	851:854	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	57	theme	full	851:854	arg1	FR					875:876	FR	875:876	FR	875:876	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	4	58	theme	fish	951:954	arg1	protein					901:907	The crude protein and crude fat content	891:929	protein	901:907	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	4	58	theme	fish	951:954	arg1	content					923:929	The crude protein and crude fat content	891:929	content	923:929	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	10	59	theme	Resistant	1737:1745	arg1	starch					1747:1752	Resistant starch	1737:1752	Resistant starch	1737:1752	Resistant starch improves dietary nitrogen and phosphorus utilization.					
36744448	8	60	theme	microbial	1630:1638	arg1	composition					1640:1650	environmental microbial composition	1616:1650	environmental microbial composition	1616:1650	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	3	61	dep	HR	832:833	arg1	%					837:837	5% starch	836:844	5% starch	836:844	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	9	62	theme	fish	1711:1714	arg1	content					1728:1734	whole fish nutritional content	1705:1734	whole fish nutritional content	1705:1734	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	1	63	theme	protein	282:288	arg1	synthesis					290:298	protein synthesis	282:298	protein synthesis	282:298	It is essential to increase the use of carbohydrates as an energy source and improve protein synthesis and utilization to reduce ammonia nitrogen emissions.					
36744448	3	64	theme	resistant	700:708	arg1	group					868:872	full replacement group	851:872	full replacement group (FR, 0% starch)	851:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	64	theme	resistant	700:708	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	64	theme	resistant	700:708	arg1	group					741:745	low replacement group	725:745	low replacement group (LR, 15% starch)	725:762	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	64	theme	resistant	700:708	arg1	group					784:788	medium replacement group	765:788	medium replacement group (MR, 10% starch)	765:805	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	64	theme	resistant	700:708	arg1	group					825:829	high replacement group	808:829	high replacement group (HR, 5% starch)	808:845	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	11	65	theme	carbon	1835:1840	arg1	source					1842:1847	a carbon source	1833:1847	a carbon source	1833:1847	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	65	theme	carbon	1835:1840	arg1	starch					1818:1823	Resistant starch	1808:1823	Resistant starch	1808:1823	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	65	theme	carbon	1835:1840	arg1	colonization					1868:1879	the colonization	1864:1879	the colonization of denitrifying bacteria in water	1864:1913	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	2	66	theme	nitrogen	505:512	arg1	budget					529:534	nitrogen and phosphorus budget	505:534	nitrogen and phosphorus budget	505:534	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	0	67	from	quality	75:81	arg1	♀ × Channa					176:185	♀ × Channa	176:185	♀ × Channa	176:185	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	67	from	quality	75:81	arg1	snakehead					149:157	hybrid snakehead	142:157	hybrid snakehead (Channa maculata ♀ × Channa argus ♂)	142:194	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	4	68	theme	hybrid	934:939	arg1	fish					951:954	hybrid snakehead fish	934:954	hybrid snakehead fish fed with the FR diet	934:975	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	3	69	dep	group	741:745	arg1	LR					748:749	LR	748:749	LR	748:749	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	69	dep	group	741:745	arg1	starch					756:761	15% starch	752:761	15% starch	752:761	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	70	theme	low	725:727	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	70	theme	low	725:727	arg1	group					741:745	low replacement group	725:745	low replacement group (LR, 15% starch)	725:762	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	0	71	theme	hybrid	142:147	arg1	♀ × Channa					176:185	♀ × Channa	176:185	♀ × Channa	176:185	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	71	theme	hybrid	142:147	arg1	snakehead					149:157	hybrid snakehead	142:157	hybrid snakehead (Channa maculata ♀ × Channa argus ♂)	142:194	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	10	72	theme	nitrogen	1771:1778	arg1	utilization					1795:1805	dietary nitrogen and phosphorus utilization	1763:1805	dietary nitrogen and phosphorus utilization	1763:1805	Resistant starch improves dietary nitrogen and phosphorus utilization.					
36744448	10	73	theme	phosphorus	1784:1793	arg1	utilization					1795:1805	dietary nitrogen and phosphorus utilization	1763:1805	dietary nitrogen and phosphorus utilization	1763:1805	Resistant starch improves dietary nitrogen and phosphorus utilization.					
36744448	3	74	theme	replacement	772:782	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	74	theme	replacement	772:782	arg1	group					784:788	medium replacement group	765:788	medium replacement group (MR, 10% starch)	765:805	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	2	75	theme	phosphorus	518:527	arg1	budget					529:534	nitrogen and phosphorus budget	505:534	nitrogen and phosphorus budget	505:534	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	4	76	theme	FR	969:970	arg1	diet					972:975	the FR diet	965:975	the FR diet	965:975	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	2	77	from	impact	411:416	arg1	budget					529:534	nitrogen and phosphorus budget	505:534	nitrogen and phosphorus budget	505:534	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	77	from	impact	411:416	arg1	community					550:558	microbial community	540:558	microbial community	540:558	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	77	from	impact	411:416	arg1	quality					496:502	water quality	490:502	water quality	490:502	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	11	78	theme	denitrifying	1884:1895	arg1	bacteria					1897:1904	denitrifying bacteria	1884:1904	denitrifying bacteria	1884:1904	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	11	79	from	colonization	1868:1879	arg1	water					1909:1913	water	1909:1913	water	1909:1913	Resistant starch acts as a carbon source and encourages the colonization of denitrifying bacteria in water.					
36744448	0	80	theme	nitrogen	84:91	arg1	budget					108:113	nitrogen and phosphorus budget	84:113	nitrogen and phosphorus budget	84:113	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	2	81	dep	meal	444:447	arg1	japonica					460:467	Laminaria japonica	450:467	Laminaria japonica	450:467	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	8	82	theme	water	1587:1591	arg1	pollution					1593:1601	water pollution	1587:1601	water pollution	1587:1601	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	3	83	theme	15	752:753	arg1	%					754:754	%	754:754	%	754:754	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	0	84	theme	phosphorus	97:106	arg1	budget					108:113	nitrogen and phosphorus budget	84:113	nitrogen and phosphorus budget	84:113	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	1	85	theme	nitrogen	334:341	arg1	emissions					343:351	ammonia nitrogen emissions	326:351	ammonia nitrogen emissions	326:351	It is essential to increase the use of carbohydrates as an energy source and improve protein synthesis and utilization to reduce ammonia nitrogen emissions.					
36744448	7	86	from	FR	1436:1437	arg1	prevalent					1417:1425	prevalent	1417:1425	prevalent	1417:1425	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	9	87	dep	POINTS	1666:1671	arg1	improves					1696:1703	improves	1696:1703	improves whole fish nutritional content	1696:1734	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	5	88	theme	nitrogen	1088:1095	arg1	effectiveness					1071:1083	the effectiveness	1067:1083	the effectiveness of nitrogen and phosphorus utilization	1067:1122	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	2	89	theme	cultural	363:370	arg1	experiment					372:381	A 60-day cultural experiment	354:381	A 60-day cultural experiment	354:381	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	6	90	theme	phosphorus	1256:1265	arg1	rate					1276:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate	1231:1279	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	8	91	theme	environmental	1616:1628	arg1	composition					1640:1650	environmental microbial composition	1616:1650	environmental microbial composition	1616:1650	In general, replacing starch with resistant starch can enhance the rate at which nitrogen and phosphorus are used in feeding, lessening water pollution and altering environmental microbial composition.					
36744448	3	92	theme	%	797:797	arg1	starch					799:804	10% starch	795:804	10% starch	795:804	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	92	theme	%	797:797	arg1	MR					791:792	MR	791:792	MR	791:792	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	5	93	from	proportion	1166:1175	arg1	water					1224:1228	tail water	1219:1228	tail water	1219:1228	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	0	94	theme	resistant	22:30	arg1	starch					32:37	resistant starch	22:37	resistant starch (Laminaria japonica)	22:58	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	94	theme	resistant	22:30	arg1	japonica					50:57	Laminaria japonica	40:57	Laminaria japonica	40:57	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	5	95	theme	hybrid	1127:1132	arg1	snakeheads					1134:1143	hybrid snakeheads	1127:1143	hybrid snakeheads	1127:1143	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	3	96	dep	C	676:676	arg1	%					681:681	20% starch	679:688	20% starch	679:688	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	97	theme	high	808:811	arg1	groups					717:722	four resistant starch groups	695:722	four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch)	695:888	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	97	theme	high	808:811	arg1	HR					832:833	HR	832:833	HR	832:833	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	3	97	theme	high	808:811	arg1	group					825:829	high replacement group	808:829	high replacement group (HR, 5% starch)	808:845	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
36744448	2	98	theme	kelp	439:442	arg1	starch					431:436	resistant starch	421:436	resistant starch (kelp meal, Laminaria japonica) replacing starch	421:485	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	98	theme	kelp	439:442	arg1	meal					444:447	kelp meal	439:447	kelp meal	439:447	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	2	99	theme	starch	431:436	arg1	impact					411:416	the impact	407:416	the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead	407:578	A 60-day cultural experiment was conducted to assess the impact of resistant starch (kelp meal, Laminaria japonica) replacing starch on water quality, nitrogen and phosphorus budget and microbial community of hybrid snakehead.					
36744448	5	100	theme	phosphorus	1205:1214	arg1	proportion					1166:1175	the proportion	1162:1175	the proportion of total nitrogen and total phosphorus in tail water	1162:1228	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	7	101	theme	Denitrifying	1317:1328	arg1	Emticicia					1375:1383	Emticicia	1375:1383	Emticicia	1375:1383	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	7	101	theme	Denitrifying	1317:1328	arg1	Rhodobacter					1362:1372	Rhodobacter	1362:1372	Rhodobacter	1362:1372	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	7	101	theme	Denitrifying	1317:1328	arg1	Bosea					1389:1393	Bosea	1389:1393	Bosea	1389:1393	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	7	101	theme	Denitrifying	1317:1328	arg1	microbes					1330:1337	Denitrifying microbes	1317:1337	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea	1317:1393	Denitrifying microbes including Gemmobacter, Rhodobacter, Emticicia and Bosea have become much more prevalent in group FR (P < 0.05).					
36744448	4	102	theme	crude	895:899	arg1	protein					901:907	The crude protein and crude fat content	891:929	protein	901:907	The crude protein and crude fat content of hybrid snakehead fish fed with the FR diet had the most significant improvement (P < 0.05).					
36744448	0	103	from	community	129:137	arg1	♀ × Channa					176:185	♀ × Channa	176:185	♀ × Channa	176:185	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	0	103	from	community	129:137	arg1	snakehead					149:157	hybrid snakehead	142:157	hybrid snakehead (Channa maculata ♀ × Channa argus ♂)	142:194	Replacing starch with resistant starch (Laminaria japonica) improves water quality, nitrogen and phosphorus budget and microbial community in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).					
36744448	6	104	theme	starch	1294:1299	arg1	level					1301:1305	the starch level	1290:1305	the starch level	1290:1305	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	6	104	theme	starch	1294:1299	arg1	%					1314:1314	6.1%	1311:1314	6.1%	1311:1314	The minimum nitrogen and phosphorus emission rate was when the starch level was 6.1%.					
36744448	9	105	theme	Resistant	1674:1682	arg1	RS					1692:1693	RS	1692:1693	RS	1692:1693	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	9	105	theme	Resistant	1674:1682	arg1	starch					1684:1689	Resistant starch	1674:1689	Resistant starch (RS)	1674:1694	PRACTITIONER POINTS: Resistant starch (RS) improves whole fish nutritional content.					
36744448	5	106	theme	total	1180:1184	arg1	nitrogen					1186:1193	total nitrogen	1180:1193	total nitrogen	1180:1193	However, resistant starch also increased the effectiveness of nitrogen and phosphorus utilization in hybrid snakeheads, which decreased the proportion of total nitrogen and total phosphorus in tail water.					
36744448	3	107	dep	FR	875:876	arg1	%					880:880	0% starch	879:887	0% starch	879:887	Approximately 1350 experimental fish (11.4 ± 0.15 g) were randomly divided into control group (C, 20% starch) and four resistant starch groups: low replacement group (LR, 15% starch), medium replacement group (MR, 10% starch), high replacement group (HR, 5% starch) and full replacement group (FR, 0% starch).					
37014547	4	0	theme	blood-brain	926:936	arg1	barrier					938:944	the blood-brain barrier	922:944	the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'	922:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	14	1	theme	reduced	2806:2812	arg1	uptake					2832:2837	a minor reduced in vitro cellular uptake	2798:2837	a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts	2798:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	4	2	theme	horse	1104:1108	arg1	principle					1071:1079	the principle	1067:1079	the principle of a 'molecular Trojan horse'	1067:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	3	3	theme	receptor	716:723	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	3	theme	receptor	716:723	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	2	4	theme	Drug	360:363	arg1	Administration					365:378	Drug Administration	360:378	Drug Administration	360:378	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	11	5	theme	monkeys	2225:2231	arg1	brain					2205:2209	brain	2205:2209	brain	2205:2209	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	11	5	theme	monkeys	2225:2231	arg1	tissues					2193:2199	tissues	2193:2199	tissues	2193:2199	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	17	6	theme	neurological	3647:3658	arg1	type					3682:3685	neurological mucopolysaccharidosis type II	3647:3688	neurological mucopolysaccharidosis type II	3647:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	8	7	theme	marketed	1788:1795	arg1	Elaprase®					1809:1817	the marketed IDS product Elaprase®	1784:1817	the marketed IDS product Elaprase® (IDS RP)	1784:1826	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	7	theme	marketed	1788:1795	arg1	RP					1824:1825	IDS RP	1820:1825	IDS RP	1820:1825	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	3	8	theme	modified	759:766	arg1	iduronate-2-sulfatase					768:788	recombinant modified iduronate-2-sulfatase	747:788	recombinant modified iduronate-2-sulfatase	747:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	11	9	theme	RP	2183:2184	arg1	distribution					2129:2140	the distribution	2125:2140	the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys	2125:2231	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	11	10	theme	IDS	2179:2181	arg1	RP					2183:2184	IDS RP	2179:2184	IDS RP	2179:2184	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	1	11	theme	enzyme	275:280	arg1	iduronate-2-sulfatase					282:302	the enzyme iduronate-2-sulfatase	271:302	the enzyme iduronate-2-sulfatase	271:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	11	12	from	distribution	2129:2140	arg1	brain					2205:2209	brain	2205:2209	brain	2205:2209	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	11	12	from	distribution	2129:2140	arg1	tissues					2193:2199	tissues	2193:2199	tissues	2193:2199	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	10	13	theme	surface	2081:2087	arg1	resonance					2097:2105	surface plasmon resonance	2081:2105	surface plasmon resonance	2081:2105	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	17	14	theme	promising	3565:3573	arg1	HIR-Fab-IDS					3501:3511	HIR-Fab-IDS	3501:3511	HIR-Fab-IDS	3501:3511	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	17	14	theme	promising	3565:3573	arg1	candidate					3575:3583	a promising candidate	3563:3583	a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II	3563:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	10	15	theme	enzyme-linked	2043:2055	arg1	assay					2071:2075	an enzyme-linked immunosorbent assay	2040:2075	an enzyme-linked immunosorbent assay	2040:2075	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	4	16	with	interaction	837:847	arg1	receptor					872:879	the human insulin receptor	854:879	the human insulin receptor	854:879	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	6	17	theme	receptor	1317:1324	arg1	fragment					1330:1337	an anti-human insulin receptor Fab fragment	1295:1337	an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase	1295:1380	HIR-Fab-IDS consists of an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase.					
37014547	2	18	theme	approved	332:339	arg1	able					504:507	able	504:507	able	504:507	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	18	theme	approved	332:339	arg1	product					324:330	The only medicinal product	305:330	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy	305:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	18	theme	approved	332:339	arg1	molecule					483:490	a large molecule	475:490	a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	475:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	18	theme	approved	332:339	arg1	iduronate-2-sulfatase					424:444	recombinant iduronate-2-sulfatase	412:444	recombinant iduronate-2-sulfatase (idursulfase, Elaprase®)	412:469	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	16	19	theme	human	3253:3257	arg1	receptors					3278:3286	human and monkey insulin receptors	3253:3286	human and monkey insulin receptors	3253:3286	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	4	20	theme	molecule	985:992	arg1	internalization					955:969	internalization	955:969	internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'	955:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	0	21	theme	Type	133:136	arg1	Treatment					86:94	the Treatment	82:94	the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)	82:157	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	2	22	theme	medicinal	314:322	arg1	able					504:507	able	504:507	able	504:507	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	22	theme	medicinal	314:322	arg1	product					324:330	The only medicinal product	305:330	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy	305:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	22	theme	medicinal	314:322	arg1	molecule					483:490	a large molecule	475:490	a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	475:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	22	theme	medicinal	314:322	arg1	iduronate-2-sulfatase					424:444	recombinant iduronate-2-sulfatase	412:444	recombinant iduronate-2-sulfatase (idursulfase, Elaprase®)	412:469	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	16	23	theme	monkey	3263:3268	arg1	receptors					3278:3286	human and monkey insulin receptors	3253:3286	human and monkey insulin receptors	3253:3286	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	1	24	theme	severe	206:211	arg1	disease					231:237	a severe lysosomal storage disease	204:237	a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase	204:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	1	24	theme	severe	206:211	arg1	type					193:196	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	14	25	theme	products	2780:2787	arg1	patterns					2751:2758	the glycosylation patterns	2733:2758	the glycosylation patterns of the compared IDS products	2733:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	12	26	theme	~ 76.5	2526:2531	arg1	RP					2522:2523	IDS RP	2518:2523	IDS RP (~ 76.5 vs ~ 67.7%)	2518:2543	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	12	26	theme	~ 76.5	2526:2531	arg1	%					2542:2542	~ 76.5 vs ~ 67.7%	2526:2542	%	2542:2542	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	6	27	theme	insulin	1309:1315	arg1	fragment					1330:1337	an anti-human insulin receptor Fab fragment	1295:1337	an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase	1295:1380	HIR-Fab-IDS consists of an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase.					
37014547	9	28	theme	HIR-Fab-IDS	1851:1861	arg1	efficiency					1837:1846	In vivo efficiency	1829:1846	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice	1829:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	13	29	theme	×	2660:2660	arg1	106 U/μmol					2662:2671	~ 2.73 × 106 U/μmol	2653:2671	~ 2.73 × 106 U/μmol	2653:2671	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	1	30	theme	storage	223:229	arg1	disease					231:237	a severe lysosomal storage disease	204:237	a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase	204:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	1	30	theme	storage	223:229	arg1	type					193:196	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	14	31	theme	compared	2767:2774	arg1	products					2780:2787	the compared IDS products	2763:2787	the compared IDS products	2763:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	2	32	theme	nervous	591:597	arg1	system					599:604	the central nervous system	579:604	the central nervous system caused by the accumulation of glycosaminoglycans	579:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	8	33	theme	Critical	1590:1597	arg1	parameters					1607:1616	Critical quality parameters	1590:1616	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity	1590:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	15	34	from	mice	3025:3028	arg1	efficacy					2984:2991	The efficacy	2980:2991	The efficacy of HIR-Fab-IDS in IDS-deficient mice	2980:3028	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	14	35	theme	effective	2934:2942	arg1	concentration					2944:2956	half-maximal effective concentration ~ 26.0	2921:2963	half-maximal effective concentration ~ 26.0	2921:2963	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	7	36	theme	plasmon	1480:1486	arg1	resonance					1488:1496	surface plasmon resonance	1472:1496	surface plasmon resonance	1472:1496	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	13	37	theme	IDS	2645:2647	arg1	RP					2649:2650	IDS RP	2645:2650	IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol)	2645:2695	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	10	38	theme	chimeric	1981:1988	arg1	molecule					1990:1997	the chimeric molecule	1977:1997	the chimeric molecule	1977:1997	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	16	39	theme	tissues	3396:3402	arg1	parts					3362:3366	all parts	3358:3366	all parts of the brain and peripheral tissues	3358:3402	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	14	40	theme	glycosylation	2737:2749	arg1	patterns					2751:2758	the glycosylation patterns	2733:2758	the glycosylation patterns of the compared IDS products	2733:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	9	41	theme	type	1898:1901	arg1	pathology					1906:1914	mucopolysaccharidosis type II pathology	1876:1914	mucopolysaccharidosis type II pathology in IDS-deficient mice	1876:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	5	42	from	OBJECTIVES	1112:1121	arg1	work					1131:1134	this work	1126:1134	this work	1126:1134	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	12	43	theme	~ 67.7	2536:2541	arg1	RP					2522:2523	IDS RP	2518:2523	IDS RP (~ 76.5 vs ~ 67.7%)	2518:2543	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	12	43	theme	~ 67.7	2536:2541	arg1	%					2542:2542	~ 76.5 vs ~ 67.7%	2526:2542	%	2542:2542	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	16	44	theme	intravenous	3410:3420	arg1	administration					3422:3435	intravenous administration	3410:3435	intravenous administration to cynomolgus monkeys	3410:3457	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	13	45	dep	RP	2649:2650	arg1	106 U/μmol					2662:2671	~ 2.73 × 106 U/μmol	2653:2671	~ 2.73 × 106 U/μmol	2653:2671	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	13	45	dep	RP	2649:2650	arg1	106 U/μmol					2685:2694	~ 2.16 × 106 U/μmol	2676:2694	~ 2.16 × 106 U/μmol	2676:2694	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	8	46	theme	therapeutic	1637:1647	arg1	effect					1649:1654	the therapeutic effect	1633:1654	the therapeutic effect of iduronate-2-sulfatase	1633:1679	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	11	47	theme	intravenous	2239:2249	arg1	administration					2251:2264	intravenous administration	2239:2264	intravenous administration	2239:2264	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	17	48	theme	novel	3516:3520	arg1	HIR-Fab-IDS					3501:3511	HIR-Fab-IDS	3501:3511	HIR-Fab-IDS	3501:3511	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	17	48	theme	novel	3516:3520	arg1	protein					3551:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	1	49	theme	BACKGROUND	160:169	arg1	disease					231:237	a severe lysosomal storage disease	204:237	a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase	204:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	1	49	theme	BACKGROUND	160:169	arg1	type					193:196	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	15	50	from	reduction	3075:3083	arg1	level					3092:3096	the level	3088:3096	the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals	3088:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	4	51	theme	endothelial	1015:1025	arg1	cells					1027:1031	endothelial cells	1015:1031	endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'	1015:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	11	52	theme	125I-radiolabeled	2145:2161	arg1	HIR-Fab-IDS					2163:2173	125I-radiolabeled HIR-Fab-IDS	2145:2173	125I-radiolabeled HIR-Fab-IDS	2145:2173	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	17	53	dep	CONCLUSIONS	3460:3470	arg1	indicate					3487:3494	indicate	3487:3494	indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II	3487:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	17	54	theme	fusion	3544:3549	arg1	HIR-Fab-IDS					3501:3511	HIR-Fab-IDS	3501:3511	HIR-Fab-IDS	3501:3511	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	17	54	theme	fusion	3544:3549	arg1	protein					3551:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	4	55	theme	adjacent	1033:1040	arg1	cells					1027:1031	endothelial cells	1015:1031	endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'	1015:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	16	56	theme	in	3231:3232	arg1	affinity					3240:3247	high in vitro affinity	3226:3247	high in vitro affinity for human and monkey insulin receptors	3226:3286	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	15	57	theme	main	3152:3155	arg1	organs					3157:3162	the main organs	3148:3162	the main organs to the level of healthy animals	3148:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	17	58	from	treatment	3593:3601	arg1	type					3682:3685	neurological mucopolysaccharidosis type II	3647:3688	neurological mucopolysaccharidosis type II	3647:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	2	59	theme	recombinant	412:422	arg1	product					324:330	The only medicinal product	305:330	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy	305:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	59	theme	recombinant	412:422	arg1	idursulfase					447:457	idursulfase	447:457	idursulfase	447:457	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	59	theme	recombinant	412:422	arg1	iduronate-2-sulfatase					424:444	recombinant iduronate-2-sulfatase	412:444	recombinant iduronate-2-sulfatase (idursulfase, Elaprase®)	412:469	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	0	60	theme	Neuropathic	99:109	arg1	Type					133:136	Neuropathic Mucopolysaccharidosis Type II	99:139	Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)	99:157	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	0	60	theme	Neuropathic	99:109	arg1	Syndrome					149:156	Hunter Syndrome	142:156	Hunter Syndrome	142:156	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	2	61	dep	US	348:349	arg1	Food					351:354	Food	351:354	Food	351:354	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	61	dep	US	348:349	arg1	Administration					365:378	Drug Administration	360:378	Drug Administration	360:378	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	1	62	theme	iduronate-2-sulfatase	282:302	arg1	activity					259:266	deficient activity	249:266	deficient activity of the enzyme iduronate-2-sulfatase	249:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	13	63	theme	enzyme	2581:2586	arg1	activity					2588:2595	the specific enzyme activity	2568:2595	the specific enzyme activity of HIR-Fab-IDS	2568:2610	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	13	63	theme	enzyme	2581:2586	arg1	higher					2625:2630	higher	2625:2630	higher	2625:2630	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	7	64	theme	modern	1443:1448	arg1	spectrometry					1507:1518	mass spectrometry	1502:1518	mass spectrometry	1502:1518	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	7	64	theme	modern	1443:1448	arg1	resonance					1488:1496	surface plasmon resonance	1472:1496	surface plasmon resonance	1472:1496	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	7	64	theme	modern	1443:1448	arg1	techniques					1450:1459	modern techniques	1443:1459	modern techniques (including surface plasmon resonance and mass spectrometry)	1443:1519	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	4	65	theme	Trojan	1097:1102	arg1	horse					1104:1108	a 'molecular Trojan horse'	1084:1109	a 'molecular Trojan horse'	1084:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	8	66	theme	IDS	1693:1695	arg1	activity					1707:1714	IDS enzymatic activity	1693:1714	IDS enzymatic activity	1693:1714	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	17	67	theme	mucopolysaccharidosis	3660:3680	arg1	type					3682:3685	neurological mucopolysaccharidosis type II	3647:3688	neurological mucopolysaccharidosis type II	3647:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	15	68	from	urine	3127:3131	arg1	level					3092:3096	the level	3088:3096	the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals	3088:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	14	69	theme	type	2879:2882	arg1	fibroblasts					2887:2897	mucopolysaccharidosis type II fibroblasts	2857:2897	mucopolysaccharidosis type II fibroblasts	2857:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	0	70	theme	Fusion	63:68	arg1	Protein					70:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	17	71	theme	manifestations	3629:3642	arg1	treatment					3593:3601	the treatment	3589:3601	the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II	3589:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	5	72	theme	barrier-penetrating	1206:1224	arg1	protein					1233:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	15	73	from	tissues	3137:3143	arg1	level					3092:3096	the level	3088:3096	the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals	3088:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	7	74	theme	Comprehensive	1391:1403	arg1	characterization					1416:1431	Comprehensive analytical characterization	1391:1431	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry)	1383:1519	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	2	75	theme	large	477:481	arg1	able					504:507	able	504:507	able	504:507	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	75	theme	large	477:481	arg1	product					324:330	The only medicinal product	305:330	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy	305:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	75	theme	large	477:481	arg1	molecule					483:490	a large molecule	475:490	a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	475:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	8	76	theme	in	1720:1721	arg1	activity					1741:1748	in vitro cell uptake activity	1720:1748	in vitro cell uptake activity	1720:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	3	77	theme	chimeric	662:669	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	77	theme	chimeric	662:669	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	10	78	link	enzyme-linked	2043:2055	arg1	assay					2071:2075	an enzyme-linked immunosorbent assay	2040:2075	an enzyme-linked immunosorbent assay	2040:2075	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	0	79	theme	Iduronate	41:49	arg1	Protein					70:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	5	80	theme	protein	1233:1239	arg1	OBJECTIVES					1112:1121	OBJECTIVES	1112:1121	OBJECTIVES In this work	1112:1134	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	5	80	theme	protein	1233:1239	arg1	characterization					1172:1187	the physicochemical and biological characterization	1137:1187	the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein	1137:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	9	81	from	pathology	1906:1914	arg1	mice					1933:1936	IDS-deficient mice	1919:1936	IDS-deficient mice	1919:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	12	82	dep	RESULTS	2267:2273	arg1	showed					2323:2328	showed	2323:2328	showed	2323:2328	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	8	83	theme	cell	1729:1732	arg1	activity					1741:1748	in vitro cell uptake activity	1720:1748	in vitro cell uptake activity	1720:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	3	84	theme	insulin	708:714	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	84	theme	insulin	708:714	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	12	85	theme	post-translational	2345:2362	arg1	modifications					2364:2376	no significant post-translational modifications	2330:2376	no significant post-translational modifications that could affect IDS activity	2330:2407	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	17	86	theme	nervous	3614:3620	arg1	system					3622:3627	central nervous system	3606:3627	central nervous system manifestations in neurological mucopolysaccharidosis type II	3606:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	8	87	theme	IDS	1797:1799	arg1	Elaprase®					1809:1817	the marketed IDS product Elaprase®	1784:1817	the marketed IDS product Elaprase® (IDS RP)	1784:1826	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	87	theme	IDS	1797:1799	arg1	RP					1824:1825	IDS RP	1820:1825	IDS RP	1820:1825	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	15	88	theme	significant	3063:3073	arg1	reduction					3075:3083	a statistically significant reduction	3047:3083	a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals	3047:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	14	89	theme	cellular	2823:2830	arg1	uptake					2832:2837	a minor reduced in vitro cellular uptake	2798:2837	a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts	2798:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	4	90	theme	insulin	864:870	arg1	receptor					872:879	the human insulin receptor	854:879	the human insulin receptor	854:879	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	16	91	dep	brain	3375:3379	arg1	the					3371:3373	the	3371:3373	the	3371:3373	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	2	92	theme	enzyme	384:389	arg1	therapy					403:409	enzyme replacement therapy	384:409	enzyme replacement therapy	384:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	14	93	located	found	2724:2728	arg2	differences					2707:2717	differences	2707:2717	differences	2707:2717	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	14	93	located	found	2724:2728	arg1	patterns					2751:2758	the glycosylation patterns	2733:2758	the glycosylation patterns of the compared IDS products	2733:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	14	94	theme	in	2814:2815	arg1	uptake					2832:2837	a minor reduced in vitro cellular uptake	2798:2837	a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts	2798:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	15	95	from	efficacy	2984:2991	arg1	mice					3025:3028	IDS-deficient mice	3011:3028	IDS-deficient mice	3011:3028	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	10	96	theme	immunosorbent	2057:2069	arg1	assay					2071:2075	an enzyme-linked immunosorbent assay	2040:2075	an enzyme-linked immunosorbent assay	2040:2075	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	3	97	theme	recombinant	747:757	arg1	iduronate-2-sulfatase					768:788	recombinant modified iduronate-2-sulfatase	747:788	recombinant modified iduronate-2-sulfatase	747:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	15	98	theme	healthy	3180:3186	arg1	animals					3188:3194	healthy animals	3180:3194	healthy animals	3180:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	13	99	theme	~ 2.16	2676:2681	arg1	106 U/μmol					2685:2694	~ 2.16 × 106 U/μmol	2676:2694	~ 2.16 × 106 U/μmol	2676:2694	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	14	100	theme	minor	2800:2804	arg1	uptake					2832:2837	a minor reduced in vitro cellular uptake	2798:2837	a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts	2798:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	15	101	from	HIR-Fab-IDS	2996:3006	arg1	mice					3025:3028	IDS-deficient mice	3011:3028	IDS-deficient mice	3011:3028	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	3	102	theme	Fab	725:727	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	102	theme	Fab	725:727	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	6	103	theme	recombinant	1348:1358	arg1	iduronate-2-sulfatase					1360:1380	recombinant iduronate-2-sulfatase	1348:1380	recombinant iduronate-2-sulfatase	1348:1380	HIR-Fab-IDS consists of an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase.					
37014547	2	104	theme	only	309:312	arg1	able					504:507	able	504:507	able	504:507	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	104	theme	only	309:312	arg1	product					324:330	The only medicinal product	305:330	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy	305:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	104	theme	only	309:312	arg1	molecule					483:490	a large molecule	475:490	a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	475:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	2	104	theme	only	309:312	arg1	iduronate-2-sulfatase					424:444	recombinant iduronate-2-sulfatase	412:444	recombinant iduronate-2-sulfatase (idursulfase, Elaprase®)	412:469	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	16	105	theme	labeled	3311:3317	arg1	product					3319:3325	the radioactively labeled product	3293:3325	the radioactively labeled product	3293:3325	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	2	106	theme	system	599:604	arg1	damage					569:574	progressive damage	557:574	progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	557:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	17	107	from	type	3682:3685	arg1	treatment					3593:3601	the treatment	3589:3601	the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II	3589:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	10	108	theme	plasmon	2089:2095	arg1	resonance					2097:2105	surface plasmon resonance	2081:2105	surface plasmon resonance	2081:2105	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	11	109	theme	HIR-Fab-IDS	2163:2173	arg1	distribution					2129:2140	the distribution	2125:2140	the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys	2125:2231	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	16	110	theme	high	3226:3229	arg1	affinity					3240:3247	high in vitro affinity	3226:3247	high in vitro affinity for human and monkey insulin receptors	3226:3286	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	1	111	theme	Mucopolysaccharidosis	171:191	arg1	disease					231:237	a severe lysosomal storage disease	204:237	a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase	204:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	1	111	theme	Mucopolysaccharidosis	171:191	arg1	type					193:196	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	7	112	theme	HIR-Fab-IDS	1577:1587	arg1	batches					1566:1572	preclinical and clinical batches	1541:1572	preclinical and clinical batches of HIR-Fab-IDS	1541:1587	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	2	113	theme	glycosaminoglycans	636:653	arg1	accumulation					620:631	the accumulation	616:631	the accumulation of glycosaminoglycans	616:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	7	114	theme	clinical	1557:1564	arg1	batches					1566:1572	preclinical and clinical batches	1541:1572	preclinical and clinical batches of HIR-Fab-IDS	1541:1587	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	12	115	theme	structure	2299:2307	arg1	investigation					2309:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	4	116	theme	nervous	1049:1055	arg1	system					1057:1062	the nervous system	1045:1062	the nervous system by the principle of a 'molecular Trojan horse'	1045:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	6	117	theme	Fab	1326:1328	arg1	fragment					1330:1337	an anti-human insulin receptor Fab fragment	1295:1337	an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase	1295:1380	HIR-Fab-IDS consists of an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase.					
37014547	13	118	theme	×	2683:2683	arg1	106 U/μmol					2685:2694	~ 2.16 × 106 U/μmol	2676:2694	~ 2.16 × 106 U/μmol	2676:2694	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	7	119	theme	preclinical	1541:1551	arg1	batches					1566:1572	preclinical and clinical batches	1541:1572	preclinical and clinical batches of HIR-Fab-IDS	1541:1587	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	17	120	from	manifestations	3629:3642	arg1	type					3682:3685	neurological mucopolysaccharidosis type II	3647:3688	neurological mucopolysaccharidosis type II	3647:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	12	121	theme	IDS	2396:2398	arg1	activity					2400:2407	IDS activity	2396:2407	IDS activity	2396:2407	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	2	122	theme	progressive	557:567	arg1	damage					569:574	progressive damage	557:574	progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans	557:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	0	123	theme	Hunter	142:147	arg1	Type					133:136	Neuropathic Mucopolysaccharidosis Type II	99:139	Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)	99:157	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	0	123	theme	Hunter	142:147	arg1	Syndrome					149:156	Hunter Syndrome	142:156	Hunter Syndrome	142:156	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	1	124	theme	lysosomal	213:221	arg1	disease					231:237	a severe lysosomal storage disease	204:237	a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase	204:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	1	124	theme	lysosomal	213:221	arg1	type					193:196	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II	160:199	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
37014547	14	125	theme	IDS	2776:2778	arg1	products					2780:2787	the compared IDS products	2763:2787	the compared IDS products	2763:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	8	126	theme	quality	1599:1605	arg1	parameters					1607:1616	Critical quality parameters	1590:1616	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity	1590:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	6	127	theme	anti-human	1298:1307	arg1	fragment					1330:1337	an anti-human insulin receptor Fab fragment	1295:1337	an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase	1295:1380	HIR-Fab-IDS consists of an anti-human insulin receptor Fab fragment fused to recombinant iduronate-2-sulfatase.					
37014547	12	128	theme	HIR-Fab-IDS	2279:2289	arg1	investigation					2309:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	9	129	theme	IDS-deficient	1919:1931	arg1	mice					1933:1936	IDS-deficient mice	1919:1936	IDS-deficient mice	1919:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	8	130	dep	in	1720:1721	arg1	vitro					1723:1727	vitro	1723:1727	vitro	1723:1727	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	16	131	theme	cynomolgus	3440:3449	arg1	monkeys					3451:3457	cynomolgus monkeys	3440:3457	cynomolgus monkeys	3440:3457	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	2	132	theme	central	583:589	arg1	system					599:604	the central nervous system	579:604	the central nervous system caused by the accumulation of glycosaminoglycans	579:653	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	12	133	theme	IDS	2518:2520	arg1	RP					2522:2523	IDS RP	2518:2523	IDS RP (~ 76.5 vs ~ 67.7%)	2518:2543	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	12	133	theme	IDS	2518:2520	arg1	%					2542:2542	~ 76.5 vs ~ 67.7%	2526:2542	%	2542:2542	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	7	134	theme	mass	1502:1505	arg1	spectrometry					1507:1518	mass spectrometry	1502:1518	mass spectrometry	1502:1518	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	0	135	dep	HIR-Fab-IDS	22:32	arg1	Novel					35:39	Novel	35:39	Novel	35:39	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	10	136	theme	molecule	1990:1997	arg1	affinity					1965:1972	The affinity	1961:1972	The affinity of the chimeric molecule for the INSR	1961:2010	The affinity of the chimeric molecule for the INSR was also determined by both an enzyme-linked immunosorbent assay and surface plasmon resonance.					
37014547	16	137	theme	brain	3375:3379	arg1	parts					3362:3366	all parts	3358:3366	all parts of the brain and peripheral tissues	3358:3402	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	9	138	theme	mucopolysaccharidosis	1876:1896	arg1	type					1898:1901	mucopolysaccharidosis type II	1876:1904	mucopolysaccharidosis type II pathology in IDS-deficient mice	1876:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	14	139	theme	half-maximal	2921:2932	arg1	concentration					2944:2956	half-maximal effective concentration ~ 26.0	2921:2963	half-maximal effective concentration ~ 26.0	2921:2963	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	14	140	dep	in	2814:2815	arg1	vitro					2817:2821	vitro	2817:2821	vitro	2817:2821	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	0	141	theme	Protein	70:76	arg1	Characterization					0:15	Characterization	0:15	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).	0:158	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	11	142	theme	cynomolgus	2214:2223	arg1	monkeys					2225:2231	cynomolgus monkeys	2214:2231	cynomolgus monkeys	2214:2231	We also compared the distribution of 125I-radiolabeled HIR-Fab-IDS and IDS RP in the tissues and brain of cynomolgus monkeys after intravenous administration.					
37014547	16	143	theme	peripheral	3385:3394	arg1	tissues					3396:3402	peripheral tissues	3385:3402	peripheral tissues	3385:3402	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	15	144	theme	glycosaminoglycans	3101:3118	arg1	level					3092:3096	the level	3088:3096	the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals	3088:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	7	145	theme	surface	1472:1478	arg1	resonance					1488:1496	surface plasmon resonance	1472:1496	surface plasmon resonance	1472:1496	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	14	146	gly	glycosylation	2737:2749	arg1	products					2780:2787	the compared IDS products	2763:2787	the compared IDS products	2763:2787	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	9	147	dep	In	1829:1830	arg1	vivo					1832:1835	vivo	1832:1835	vivo	1832:1835	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	4	148	theme	hybrid	978:983	arg1	molecule					985:992	the hybrid molecule	974:992	the hybrid molecule	974:992	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	8	149	theme	iduronate-2-sulfatase	1659:1679	arg1	activity					1707:1714	IDS enzymatic activity	1693:1714	IDS enzymatic activity	1693:1714	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	149	theme	iduronate-2-sulfatase	1659:1679	arg1	activity					1741:1748	in vitro cell uptake activity	1720:1748	in vitro cell uptake activity	1720:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	149	theme	iduronate-2-sulfatase	1659:1679	arg1	effect					1649:1654	the therapeutic effect	1633:1654	the therapeutic effect of iduronate-2-sulfatase	1633:1679	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	17	150	theme	iduronate-2-sulfatase	3522:3542	arg1	HIR-Fab-IDS					3501:3511	HIR-Fab-IDS	3501:3511	HIR-Fab-IDS	3501:3511	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	17	150	theme	iduronate-2-sulfatase	3522:3542	arg1	protein					3551:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	a novel iduronate-2-sulfatase fusion protein	3514:3557	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	5	151	theme	blood-brain	1194:1204	arg1	protein					1233:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	13	152	theme	HIR-Fab-IDS	2600:2610	arg1	activity					2588:2595	the specific enzyme activity	2568:2595	the specific enzyme activity of HIR-Fab-IDS	2568:2610	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	13	152	theme	HIR-Fab-IDS	2600:2610	arg1	higher					2625:2630	higher	2625:2630	higher	2625:2630	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	8	153	with	comparison	1768:1777	arg1	Elaprase®					1809:1817	the marketed IDS product Elaprase®	1784:1817	the marketed IDS product Elaprase® (IDS RP)	1784:1826	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	153	with	comparison	1768:1777	arg1	RP					1824:1825	IDS RP	1820:1825	IDS RP	1820:1825	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	2	154	theme	blood-brain	522:532	arg1	barrier					534:540	the blood-brain barrier	518:540	the blood-brain barrier	518:540	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	15	155	theme	IDS-deficient	3011:3023	arg1	mice					3025:3028	IDS-deficient mice	3011:3028	IDS-deficient mice	3011:3028	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	12	156	theme	formylglycine	2425:2437	arg1	higher					2472:2477	higher	2472:2477	higher	2472:2477	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	12	156	theme	formylglycine	2425:2437	arg1	content					2439:2445	the formylglycine content	2421:2445	the formylglycine content	2421:2445	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	0	157	theme	Mucopolysaccharidosis	111:131	arg1	Type					133:136	Neuropathic Mucopolysaccharidosis Type II	99:139	Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)	99:157	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	0	157	theme	Mucopolysaccharidosis	111:131	arg1	Syndrome					149:156	Hunter Syndrome	142:156	Hunter Syndrome	142:156	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	5	158	theme	physicochemical	1141:1155	arg1	OBJECTIVES					1112:1121	OBJECTIVES	1112:1121	OBJECTIVES In this work	1112:1134	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	5	158	theme	physicochemical	1141:1155	arg1	characterization					1172:1187	the physicochemical and biological characterization	1137:1187	the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein	1137:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	15	159	from	level	3092:3096	arg1	tissues					3137:3143	tissues	3137:3143	tissues	3137:3143	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	15	159	from	level	3092:3096	arg1	urine					3127:3131	urine	3127:3131	urine	3127:3131	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	14	160	theme	IDS	2913:2915	arg1	RP					2917:2918	IDS RP	2913:2918	IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM)	2913:2977	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	4	161	theme	selective	827:835	arg1	interaction					837:847	a highly selective interaction	818:847	a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'	818:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	5	162	theme	biological	1161:1170	arg1	OBJECTIVES					1112:1121	OBJECTIVES	1112:1121	OBJECTIVES In this work	1112:1134	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	5	162	theme	biological	1161:1170	arg1	characterization					1172:1187	the physicochemical and biological characterization	1137:1187	the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein	1137:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	13	163	theme	specific	2572:2579	arg1	activity					2588:2595	the specific enzyme activity	2568:2595	the specific enzyme activity of HIR-Fab-IDS	2568:2610	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	13	163	theme	specific	2572:2579	arg1	higher					2625:2630	higher	2625:2630	higher	2625:2630	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	15	164	from	glycosaminoglycans	3101:3118	arg1	tissues					3137:3143	tissues	3137:3143	tissues	3137:3143	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	15	164	from	glycosaminoglycans	3101:3118	arg1	urine					3127:3131	urine	3127:3131	urine	3127:3131	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	15	165	theme	organs	3157:3162	arg1	tissues					3137:3143	tissues	3137:3143	tissues	3137:3143	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	15	165	theme	organs	3157:3162	arg1	urine					3127:3131	urine	3127:3131	urine	3127:3131	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	13	166	theme	~ 2.73	2653:2658	arg1	106 U/μmol					2662:2671	~ 2.73 × 106 U/μmol	2653:2671	~ 2.73 × 106 U/μmol	2653:2671	Because of this fact, the specific enzyme activity of HIR-Fab-IDS was slightly higher than that of IDS RP (~ 2.73 × 106 U/μmol vs ~ 2.16 × 106 U/μmol).					
37014547	8	167	theme	enzymatic	1697:1705	arg1	activity					1707:1714	IDS enzymatic activity	1693:1714	IDS enzymatic activity	1693:1714	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	2	168	theme	replacement	391:401	arg1	therapy					403:409	enzyme replacement therapy	384:409	enzyme replacement therapy	384:409	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	0	169	theme	HIR-Fab-IDS	22:32	arg1	Protein					70:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	16	170	theme	insulin	3270:3276	arg1	receptors					3278:3286	human and monkey insulin receptors	3253:3286	human and monkey insulin receptors	3253:3286	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	7	171	theme	analytical	1405:1414	arg1	characterization					1416:1431	Comprehensive analytical characterization	1391:1431	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry)	1383:1519	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	4	172	theme	molecular	1087:1095	arg1	horse					1104:1108	a 'molecular Trojan horse'	1084:1109	a 'molecular Trojan horse'	1084:1109	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	16	173	dep	in	3231:3232	arg1	vitro					3234:3238	vitro	3234:3238	vitro	3234:3238	The HIR-Fab-IDS has revealed high in vitro affinity for human and monkey insulin receptors, and the radioactively labeled product has been shown to penetrate to all parts of the brain and peripheral tissues after intravenous administration to cynomolgus monkeys.					
37014547	12	174	theme	primary	2291:2297	arg1	investigation					2309:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	The HIR-Fab-IDS primary structure investigation	2275:2321	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	14	175	theme	mucopolysaccharidosis	2857:2877	arg1	fibroblasts					2887:2897	mucopolysaccharidosis type II fibroblasts	2857:2897	mucopolysaccharidosis type II fibroblasts	2857:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	3	176	theme	Novel	656:660	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	176	theme	Novel	656:660	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	14	177	dep	RP	2917:2918	arg1	concentration					2944:2956	half-maximal effective concentration ~ 26.0	2921:2963	half-maximal effective concentration ~ 26.0	2921:2963	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	14	177	dep	RP	2917:2918	arg1	~ 23.0 nM					2968:2976	~ 23.0 nM	2968:2976	~ 23.0 nM	2968:2976	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	0	178	theme	2-Sulfatase	51:61	arg1	Protein					70:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein	20:76	Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome).					
37014547	5	179	theme	fusion	1226:1231	arg1	protein					1233:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	a blood-brain barrier-penetrating fusion protein	1192:1239	OBJECTIVES In this work, the physicochemical and biological characterization of a blood-brain barrier-penetrating fusion protein, HIR-Fab-IDS, is carried out.					
37014547	14	180	theme	HIR-Fab-IDS	2842:2852	arg1	uptake					2832:2837	a minor reduced in vitro cellular uptake	2798:2837	a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts	2798:2897	However, differences were found in the glycosylation patterns of the compared IDS products, causing a minor reduced in vitro cellular uptake of HIR-Fab-IDS by mucopolysaccharidosis type II fibroblasts compared with IDS RP (half-maximal effective concentration ~ 26.0 vs ~ 23.0 nM).					
37014547	15	181	theme	HIR-Fab-IDS	2996:3006	arg1	efficacy					2984:2991	The efficacy	2980:2991	The efficacy of HIR-Fab-IDS in IDS-deficient mice	2980:3028	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	8	182	theme	uptake	1734:1739	arg1	activity					1741:1748	in vitro cell uptake activity	1720:1748	in vitro cell uptake activity	1720:1748	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	3	183	theme	anti-human	697:706	arg1	fragment					729:736	an anti-human insulin receptor Fab fragment	694:736	an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase	694:788	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	3	183	theme	anti-human	697:706	arg1	protein					671:677	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS	656:689	Novel chimeric protein HIR-Fab-IDS is an anti-human insulin receptor Fab fragment fused to recombinant modified iduronate-2-sulfatase.					
37014547	2	184	dep	idursulfase	447:457	arg1	Elaprase®					460:468	Elaprase®	460:468	Elaprase®	460:468	The only medicinal product approved by the US Food and Drug Administration for enzyme replacement therapy, recombinant iduronate-2-sulfatase (idursulfase, Elaprase®), is a large molecule that is not able to cross the blood-brain barrier and neutralize progressive damage of the central nervous system caused by the accumulation of glycosaminoglycans.					
37014547	17	185	theme	central	3606:3612	arg1	system					3622:3627	central nervous system	3606:3627	central nervous system manifestations in neurological mucopolysaccharidosis type II	3606:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	8	186	theme	product	1801:1807	arg1	Elaprase®					1809:1817	the marketed IDS product Elaprase®	1784:1817	the marketed IDS product Elaprase® (IDS RP)	1784:1826	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	8	186	theme	product	1801:1807	arg1	RP					1824:1825	IDS RP	1820:1825	IDS RP	1820:1825	Critical quality parameters that determine the therapeutic effect of iduronate-2-sulfatase, as well as IDS enzymatic activity and in vitro cell uptake activity were evaluated in comparison with the marketed IDS product Elaprase® (IDS RP).					
37014547	9	187	theme	In	1829:1830	arg1	efficiency					1837:1846	In vivo efficiency	1829:1846	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice	1829:1936	In vivo efficiency of HIR-Fab-IDS in reversing mucopolysaccharidosis type II pathology in IDS-deficient mice was also investigated.					
37014547	7	188	dep	METHODS	1383:1389	arg1	characterization					1416:1431	Comprehensive analytical characterization	1391:1431	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry)	1383:1519	METHODS Comprehensive analytical characterization utilizing modern techniques (including surface plasmon resonance and mass spectrometry) was performed using preclinical and clinical batches of HIR-Fab-IDS.					
37014547	12	189	theme	significant	2333:2343	arg1	modifications					2364:2376	no significant post-translational modifications	2330:2376	no significant post-translational modifications that could affect IDS activity	2330:2407	RESULTS The HIR-Fab-IDS primary structure investigation showed no significant post-translational modifications that could affect IDS activity, except for the formylglycine content, which was significantly higher for HIR-Fab-IDS compared with that for IDS RP (~ 76.5 vs ~ 67.7%).					
37014547	17	190	theme	system	3622:3627	arg1	manifestations					3629:3642	central nervous system manifestations	3606:3642	central nervous system manifestations in neurological mucopolysaccharidosis type II	3606:3688	CONCLUSIONS These findings indicate that HIR-Fab-IDS, a novel iduronate-2-sulfatase fusion protein, is a promising candidate for the treatment of central nervous system manifestations in neurological mucopolysaccharidosis type II.					
37014547	15	191	theme	animals	3188:3194	arg1	level					3171:3175	the level	3167:3175	the level of healthy animals	3167:3194	The efficacy of HIR-Fab-IDS in IDS-deficient mice has demonstrated a statistically significant reduction in the level of glycosaminoglycans in the urine and tissues of the main organs to the level of healthy animals.					
37014547	4	192	theme	human	858:862	arg1	receptor					872:879	the human insulin receptor	854:879	the human insulin receptor	854:879	This modification provides a highly selective interaction with the human insulin receptor, which leads to the HIR-Fab-IDS crossing the blood-brain barrier owing to internalization of the hybrid molecule by transcytosis into endothelial cells adjacent to the nervous system by the principle of a 'molecular Trojan horse'.					
37014547	1	193	theme	deficient	249:257	arg1	activity					259:266	deficient activity	249:266	deficient activity of the enzyme iduronate-2-sulfatase	249:302	BACKGROUND Mucopolysaccharidosis type II is a severe lysosomal storage disease caused by deficient activity of the enzyme iduronate-2-sulfatase.					
35171166	5	0	theme	bonding	959:965	arg1	fibres					927:932	the citrus fibres	916:932	the citrus fibres	916:932	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	5	0	theme	bonding	959:965	arg1	type					942:945	the type	938:945	the type of hydrogen bonding	938:965	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	4	1	theme	higher	818:823	arg1	G					842:842	G'	842:843	G'	842:843	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	4	1	theme	higher	818:823	arg1	modulus					833:839	higher storage modulus	818:839	higher storage modulus (G')	818:844	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	2	2	from	influence	424:432	arg1	interactions					520:531	these interactions	514:531	these interactions	514:531	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	2	3	theme	drying	441:446	arg1	processes					465:473	the drying and purification processes	437:473	the drying and purification processes	437:473	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	1	4	theme	cellulose	317:325	arg1	properties					303:312	the structural and functional properties	273:312	the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	273:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	5	5	theme	hydrogen	950:957	arg1	bonding					959:965	hydrogen bonding	950:965	hydrogen bonding	950:965	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	3	6	theme	higher	590:595	arg1	aggregation					597:607	a higher aggregation	588:607	a higher aggregation	588:607	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	3	7	with	interactions	649:660	arg1	lignin					682:687	lignin	682:687	lignin	682:687	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	3	7	with	interactions	649:660	arg1	hemicellulose					694:706	hemicellulose	694:706	hemicellulose	694:706	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	3	7	with	interactions	649:660	arg1	pectin					674:679	pectin	674:679	pectin	674:679	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	3	7	with	interactions	649:660	arg1	water					667:671	water	667:671	water	667:671	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	5	8	theme	moisture	1085:1092	arg1	behaviour					1103:1111	the moisture sorption behaviour	1081:1111	the moisture sorption behaviour of the citrus fibres	1081:1132	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	0	9	from	Effects	0:6	arg1	properties					72:81	the structural and functional properties	42:81	the structural and functional properties of cellulose with cell wall components in different citrus fibres	42:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	10	theme	citrus	405:410	arg1	fibres					412:417	citrus fibres	405:417	citrus fibres	405:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	4	11	theme	Citrus	709:714	arg1	suspension					722:731	Citrus fibre suspension	709:731	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process	709:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	5	12	theme	sorption	1094:1101	arg1	behaviour					1103:1111	the moisture sorption behaviour	1081:1111	the moisture sorption behaviour of the citrus fibres	1081:1132	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	0	13	theme	cellulose	86:94	arg1	properties					72:81	the structural and functional properties	42:81	the structural and functional properties of cellulose with cell wall components in different citrus fibres	42:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	14	theme	cell	332:335	arg1	hemicellulose					380:392	hemicellulose	380:392	hemicellulose	380:392	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	14	theme	cell	332:335	arg1	lignin					368:373	lignin	368:373	lignin	368:373	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	14	theme	cell	332:335	arg1	materials					342:350	cell wall materials	332:350	cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	332:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	14	theme	cell	332:335	arg1	pectin					360:365	pectin	360:365	pectin	360:365	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	4	15	theme	storage	825:831	arg1	G					842:842	G'	842:843	G'	842:843	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	4	15	theme	storage	825:831	arg1	modulus					833:839	higher storage modulus	818:839	higher storage modulus (G')	818:844	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	0	16	theme	wall	106:109	arg1	components					111:120	cell wall components	101:120	cell wall components in different citrus fibres	101:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	17	theme	wall	337:340	arg1	hemicellulose					380:392	hemicellulose	380:392	hemicellulose	380:392	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	17	theme	wall	337:340	arg1	lignin					368:373	lignin	368:373	lignin	368:373	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	17	theme	wall	337:340	arg1	materials					342:350	cell wall materials	332:350	cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	332:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	17	theme	wall	337:340	arg1	pectin					360:365	pectin	360:365	pectin	360:365	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	4	18	theme	centrifugal	784:794	arg1	process					803:809	a centrifugal drying process	782:809	a centrifugal drying process	782:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	0	19	from	components	111:120	arg1	fibres					142:147	different citrus fibres	125:147	different citrus fibres	125:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	0	20	theme	cell	101:104	arg1	components					111:120	cell wall components	101:120	cell wall components in different citrus fibres	101:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	4	21	theme	fibre	716:720	arg1	suspension					722:731	Citrus fibre suspension	709:731	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process	709:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	5	22	theme	key	993:995	arg1	role					997:1000	a key role	991:1000	a key role	991:1000	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	2	23	theme	processes	465:473	arg1	influence					424:432	The influence	420:432	The influence of the drying and purification processes and the source of the citrus fibres on these interactions	420:531	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	4	24	with	combination	765:775	arg1	process					803:809	a centrifugal drying process	782:809	a centrifugal drying process	782:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	1	25	theme	multi-method	171:182	arg1	approach					184:191	a multi-method approach	169:191	a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	169:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	2	26	theme	citrus	497:502	arg1	fibres					504:509	the citrus fibres	493:509	the citrus fibres	493:509	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	3	27	theme	fibres	622:627	arg1	aggregation					597:607	a higher aggregation	588:607	a higher aggregation	588:607	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	0	28	theme	moisture	21:28	arg1	contents					30:37	different moisture contents	11:37	different moisture contents	11:37	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	4	29	theme	loss	847:850	arg1	modulus					852:858	loss modulus	847:858		847:268	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	4	29	theme	loss	847:850	arg1	"					-1:-1		861:-1		861:-1	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	0	30	with	cellulose	86:94	arg1	components					111:120	cell wall components	101:120	cell wall components in different citrus fibres	101:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	0	31	theme	different	11:19	arg1	contents					30:37	different moisture contents	11:37	different moisture contents	11:37	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	2	32	theme	fibres	504:509	arg1	processes					465:473	the drying and purification processes	437:473	the drying and purification processes	437:473	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	2	32	theme	fibres	504:509	arg1	source					483:488	the source	479:488	the source of the citrus fibres	479:509	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	5	33	theme	fibres	1127:1132	arg1	behaviour					1103:1111	the moisture sorption behaviour	1081:1111	the moisture sorption behaviour of the citrus fibres	1081:1132	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	4	34	theme	retention	876:884	arg1	capacity					886:893	water, pectin, lignin, and hemicellulose. Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity	667:893	water, pectin, lignin, and hemicellulose. Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity	667:893	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	0	35	theme	citrus	135:140	arg1	fibres					142:147	different citrus fibres	125:147	different citrus fibres	125:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	36	dep	levels	240:245	arg1	low					248:250	low	248:250	low	248:250	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	36	dep	levels	240:245	arg1	high					264:267	high	264:267	high	264:267	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	36	dep	levels	240:245	arg1	medium					253:258	medium	253:258	medium	253:258	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	5	37	theme	citrus	920:925	arg1	fibres					927:932	the citrus fibres	916:932	the citrus fibres	916:932	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	1	38	attach	present	394:400	arg1	fibres					412:417	citrus fibres	405:417	citrus fibres	405:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	38	attach	present	394:400	arg2	pectin					360:365	pectin	360:365	pectin	360:365	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	0	39	theme	contents	30:37	arg1	Effects					0:6	Effects	0:6	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres	0:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	5	40	theme	rheological	1023:1033	arg1	properties					1047:1056	stable rheological and thermal properties	1016:1056	stable rheological and thermal properties	1016:1056	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	0	41	theme	different	125:133	arg1	fibres					142:147	different citrus fibres	125:147	different citrus fibres	125:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	3	42	theme	fluidized	557:565	arg1	dryer					571:575	A fluidized bed dryer	555:575	A fluidized bed dryer	555:575	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	4	43	dep	suspension	722:731	arg1	produce					733:739	produce	733:739	produce by a alcohol washing in combination with a centrifugal drying process	733:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	0	44	theme	structural	46:55	arg1	properties					72:81	the structural and functional properties	42:81	the structural and functional properties of cellulose with cell wall components in different citrus fibres	42:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	45	theme	structural	277:286	arg1	properties					303:312	the structural and functional properties	273:312	the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	273:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	2	46	theme	purification	452:463	arg1	processes					465:473	the drying and purification processes	437:473	the drying and purification processes	437:473	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	2	47	theme	source	483:488	arg1	influence					424:432	The influence	420:432	The influence of the drying and purification processes and the source of the citrus fibres on these interactions	420:531	The influence of the drying and purification processes and the source of the citrus fibres on these interactions were also considered.					
35171166	1	48	from	influence	208:216	arg1	properties					303:312	the structural and functional properties	273:312	the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	273:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	5	49	theme	stable	1016:1021	arg1	properties					1047:1056	stable rheological and thermal properties	1016:1056	stable rheological and thermal properties	1016:1056	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	5	50	theme	thermal	1039:1045	arg1	properties					1047:1056	stable rheological and thermal properties	1016:1056	stable rheological and thermal properties	1016:1056	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	5	51	theme	type	942:945	arg1	compositions					900:911	The compositions	896:911	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR)	896:984	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	4	52	theme	water	667:671	arg1	capacity					886:893	water, pectin, lignin, and hemicellulose. Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity	667:893	water, pectin, lignin, and hemicellulose. Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity	667:893	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	1	53	theme	functional	292:301	arg1	properties					303:312	the structural and functional properties	273:312	the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	273:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	5	54	theme	fibres	927:932	arg1	compositions					900:911	The compositions	896:911	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR)	896:984	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	3	55	theme	cellulose	612:620	arg1	fibres					622:627	cellulose fibres	612:627	cellulose fibres	612:627	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	4	56	theme	G	861:861	arg1	modulus					852:858	loss modulus	847:858		847:268	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	4	56	theme	G	861:861	arg1	"					-1:-1		861:-1		861:-1	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	1	57	theme	different	221:229	arg1	levels					240:245	different moisture levels	221:245	different moisture levels (low, medium and high)	221:268	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	0	58	theme	functional	61:70	arg1	properties					72:81	the structural and functional properties	42:81	the structural and functional properties of cellulose with cell wall components in different citrus fibres	42:147	Effects of different moisture contents on the structural and functional properties of cellulose with cell wall components in different citrus fibres.					
35171166	1	59	theme	present	394:400	arg1	pectin					360:365	pectin	360:365	pectin	360:365	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	3	60	theme	bed	567:569	arg1	dryer					571:575	A fluidized bed dryer	555:575	A fluidized bed dryer	555:575	A fluidized bed dryer results in a higher aggregation of cellulose fibres, which limits their interactions with water, pectin, lignin, and hemicellulose.					
35171166	1	61	from	fibres	412:417	arg1	present					394:400	present	394:400	present	394:400	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	62	theme	moisture	231:238	arg1	levels					240:245	different moisture levels	221:245	different moisture levels (low, medium and high)	221:268	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	63	from	present	394:400	arg1	fibres					412:417	citrus fibres	405:417	citrus fibres	405:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	64	used	used	164:167	arg2	research					155:162	This research	150:162	This research	150:162	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	4	65	theme	drying	796:801	arg1	process					803:809	a centrifugal drying process	782:809	a centrifugal drying process	782:809	Citrus fibre suspension produce by a alcohol washing in combination with a centrifugal drying process showed higher storage modulus (G'), loss modulus (G'') and water retention capacity.					
35171166	5	66	theme	citrus	1120:1125	arg1	fibres					1127:1132	the citrus fibres	1116:1132	the citrus fibres	1116:1132	The compositions of the citrus fibres and the type of hydrogen bonding (analysed by FTIR) play a key role in generating stable rheological and thermal properties as well as controlling the moisture sorption behaviour of the citrus fibres.					
35171166	1	67	with	cellulose	317:325	arg1	hemicellulose					380:392	hemicellulose	380:392	hemicellulose	380:392	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	67	with	cellulose	317:325	arg1	lignin					368:373	lignin	368:373	lignin	368:373	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	67	with	cellulose	317:325	arg1	materials					342:350	cell wall materials	332:350	cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	332:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	67	with	cellulose	317:325	arg1	pectin					360:365	pectin	360:365	pectin	360:365	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
35171166	1	68	theme	levels	240:245	arg1	influence					208:216	the influence	204:216	the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres	204:417	This research used a multi-method approach to analyse the influence of different moisture levels (low, medium and high) on the structural and functional properties of cellulose with cell wall materials such as pectin, lignin, and hemicellulose present in citrus fibres.					
36736972	1	0	theme	agents	146:151	arg1	encapsulation					122:134	The encapsulation	118:134	The encapsulation of bluing agents in biodegradable polymeric capsules	118:187	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	1	0	theme	agents	146:151	arg1	option					204:209	an emerging option	192:209	an emerging option in laundry detergents sector to substitute formaldehyde-based polymers	192:280	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	2	1	dep	hydrogel	494:501	arg1	network					529:535	network	529:535	network	529:535	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	4	2	theme	properties	857:866	arg1	assessment					814:823	assessment	814:823	assessment of their mechanical and thermal properties	814:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	2	theme	properties	857:866	arg1	characterization					796:811	chemical and morphological characterization	769:811	chemical and morphological characterization	769:811	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	1	3	theme	formaldehyde-based	254:271	arg1	polymers					273:280	formaldehyde-based polymers	254:280	formaldehyde-based polymers	254:280	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	2	4	theme	polyethylene	509:520	arg1	glycol					522:527	a polyethylene glycol	507:527	a polyethylene glycol	507:527	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	1	5	from	encapsulation	122:134	arg1	capsules					180:187	biodegradable polymeric capsules	156:187	biodegradable polymeric capsules	156:187	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	4	6	theme	capsules	745:752	arg1	type					737:740	each type	732:740	each type of capsules	732:752	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	5	7	theme	obtained	1087:1094	arg1	results					1096:1102	The obtained results	1083:1102	The obtained results	1083:1102	The obtained results will serve to comprehend how the dye can be released from the capsules.					
36736972	3	8	theme	Different	538:546	arg1	types					548:552	Different types	538:552	Different types of capsules	538:564	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	0	9	theme	blue	108:111	arg1	dye					113:115	blue dye	108:115	blue dye	108:115	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	4	10	theme	mechanical	834:843	arg1	properties					857:866	their mechanical and thermal properties	828:866	their mechanical and thermal properties	828:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	3	11	dep	addition	584:591	arg1	not					596:598	not	596:598	not	596:598	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	1	12	theme	biodegradable	156:168	arg1	capsules					180:187	biodegradable polymeric capsules	156:187	biodegradable polymeric capsules	156:187	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	4	13	theme	diacrylate	945:954	arg1	PEGDMA					965:970	PEGDMA	965:970	PEGDMA	965:970	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	13	theme	diacrylate	945:954	arg1	monomer					956:962	the diacrylate monomer	941:962	the diacrylate monomer (PEGDMA)	941:971	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	1	14	theme	polymeric	170:178	arg1	capsules					180:187	biodegradable polymeric capsules	156:187	biodegradable polymeric capsules	156:187	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	2	15	theme	biodegradable	433:445	arg1	capsules					447:454	biodegradable capsules	433:454	biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network	433:535	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	4	16	theme	thermal	849:855	arg1	properties					857:866	their mechanical and thermal properties	828:866	their mechanical and thermal properties	828:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	0	17	theme	hydrogel	64:71	arg1	composite					73:81	alginate hydrogel composite	55:81	alginate hydrogel composite for the encapsulation of blue dye	55:115	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	3	18	theme	capsules	557:564	arg1	types					548:552	Different types	538:552	Different types of capsules	538:564	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	2	19	theme	first	376:380	arg1	time					382:385	the first time	372:385	the first time	372:385	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	4	20	theme	times	1007:1011	arg1	incorporation					924:936	the incorporation	920:936	the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially	920:1034	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	21	theme	irradiation	995:1005	arg1	times					1007:1011	the two different irradiation times	977:1011	the two different irradiation times selected substantially	977:1034	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	2	22	theme	dye	426:428	arg1	encapsulation					402:414	the successful encapsulation	387:414	the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network	387:535	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	3	23	dep	synthesized	571:581	arg1	addition					584:591	addition	584:591	addition	584:591	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	4	24	theme	type	737:740	arg1	characterization					712:727	a deep characterization	705:727	a deep characterization of each type of capsules	705:752	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	2	25	theme	blue	421:424	arg1	dye					426:428	a blue dye	419:428	a blue dye	419:428	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	0	26	theme	dye	113:115	arg1	encapsulation					91:103	the encapsulation	87:103	the encapsulation of blue dye	87:115	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	1	27	theme	emerging	195:202	arg1	encapsulation					122:134	The encapsulation	118:134	The encapsulation of bluing agents in biodegradable polymeric capsules	118:187	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	1	27	theme	emerging	195:202	arg1	option					204:209	an emerging option	192:209	an emerging option in laundry detergents sector to substitute formaldehyde-based polymers	192:280	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	0	28	theme	capsules	37:44	arg1	assembly					11:18	assembly	11:18	assembly	11:18	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	0	28	theme	capsules	37:44	arg1	Design					0:5	Design	0:5	Design	0:5	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	0	29	theme	biodegradable	23:35	arg1	capsules					37:44	biodegradable capsules	23:44	biodegradable capsules	23:44	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	4	30	theme	different	985:993	arg1	times					1007:1011	the two different irradiation times	977:1011	the two different irradiation times selected substantially	977:1034	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	3	31	theme	monomer	618:624	arg1	addition					584:591	addition	584:591	addition	584:591	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	1	32	from	option	204:209	arg1	detergents					222:231	laundry detergents	214:231	laundry detergents	214:231	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	2	33	theme	successful	391:400	arg1	encapsulation					402:414	the successful encapsulation	387:414	the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network	387:535	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	3	34	from	times	685:689	arg1	irradiation					631:641	irradiation	631:641	irradiation of the crosslinking solution	631:670	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	4	35	theme	biodegradability	889:904	arg1	evaluation					869:878	evaluation	869:878	evaluation of their biodegradability	869:904	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	35	theme	biodegradability	889:904	arg1	characterization					796:811	chemical and morphological characterization	769:811	chemical and morphological characterization	769:811	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	3	36	theme	different	675:683	arg1	times					685:689	different times	675:689	different times	675:689	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	3	37	theme	crosslinking	650:661	arg1	solution					663:670	the crosslinking solution	646:670	the crosslinking solution	646:670	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	4	38	theme	capsules	1073:1080	arg1	properties					1055:1064	the final properties	1045:1064	the final properties of the capsules	1045:1080	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	3	39	theme	solution	663:670	arg1	irradiation					631:641	irradiation	631:641	irradiation of the crosslinking solution	631:670	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	4	40	theme	chemical	769:776	arg1	evaluation					869:878	evaluation	869:878	evaluation of their biodegradability	869:904	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	40	theme	chemical	769:776	arg1	assessment					814:823	assessment	814:823	assessment of their mechanical and thermal properties	814:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	40	theme	chemical	769:776	arg1	characterization					796:811	chemical and morphological characterization	769:811	chemical and morphological characterization	769:811	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	41	theme	deep	707:710	arg1	characterization					712:727	a deep characterization	705:727	a deep characterization of each type of capsules	705:752	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	5	42	attach	released	1148:1155	arg2	dye					1137:1139	the dye	1133:1139	the dye	1133:1139	The obtained results will serve to comprehend how the dye can be released from the capsules.					
36736972	5	42	attach	released	1148:1155	arg1	capsules					1166:1173	the capsules	1162:1173	the capsules	1162:1173	The obtained results will serve to comprehend how the dye can be released from the capsules.					
36736972	1	43	theme	laundry	214:220	arg1	detergents					222:231	laundry detergents	214:231	laundry detergents	214:231	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	3	44	theme	diacrylate	607:616	arg1	monomer					618:624	the diacrylate monomer	603:624	the diacrylate monomer	603:624	Different types of capsules were synthesized (addition or not of the diacrylate monomer) and irradiation of the crosslinking solution at different times.					
36736972	2	45	from	encapsulation	402:414	arg1	capsules					447:454	biodegradable capsules	433:454	biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network	433:535	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	2	46	theme	alginate	485:492	arg1	hydrogel					494:501	an alginate hydrogel	482:501	an alginate hydrogel	482:501	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	4	47	theme	morphological	782:794	arg1	evaluation					869:878	evaluation	869:878	evaluation of their biodegradability	869:904	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	47	theme	morphological	782:794	arg1	assessment					814:823	assessment	814:823	assessment of their mechanical and thermal properties	814:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	47	theme	morphological	782:794	arg1	characterization					796:811	chemical and morphological characterization	769:811	chemical and morphological characterization	769:811	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	48	dep	performed	758:766	arg1	evaluation					869:878	evaluation	869:878	evaluation of their biodegradability	869:904	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	48	dep	performed	758:766	arg1	assessment					814:823	assessment	814:823	assessment of their mechanical and thermal properties	814:866	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	48	dep	performed	758:766	arg1	characterization					796:811	chemical and morphological characterization	769:811	chemical and morphological characterization	769:811	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	0	49	theme	alginate	55:62	arg1	composite					73:81	alginate hydrogel composite	55:81	alginate hydrogel composite for the encapsulation of blue dye	55:115	Design and assembly of biodegradable capsules based on alginate hydrogel composite for the encapsulation of blue dye.					
36736972	2	50	attach	present	360:366	arg2	we					357:358	we	357:358	we	357:358	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	2	50	attach	present	360:366	arg1	work					351:354	this work	346:354	this work	346:354	In this work, we present for the first time the successful encapsulation of a blue dye in biodegradable capsules which shell was formed by an alginate hydrogel and a polyethylene glycol network.					
36736972	1	51	theme	bluing	139:144	arg1	agents					146:151	bluing agents	139:151	bluing agents	139:151	The encapsulation of bluing agents in biodegradable polymeric capsules is an emerging option in laundry detergents sector to substitute formaldehyde-based polymers, because they are non-biodegradable, carcinogenic and toxic.					
36736972	4	52	theme	final	1049:1053	arg1	properties					1055:1064	the final properties	1045:1064	the final properties of the capsules	1045:1080	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36736972	4	53	theme	monomer	956:962	arg1	incorporation					924:936	the incorporation	920:936	the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially	920:1034	Furthermore, a deep characterization of each type of capsules was performed (chemical and morphological characterization, assessment of their mechanical and thermal properties, evaluation of their biodegradability), noting that the incorporation of the diacrylate monomer (PEGDMA) and the two different irradiation times selected substantially affected the final properties of the capsules.					
36372493	0	0	theme	groups	83:88	arg1	effect					62:67	the synergistic effect	46:67	the synergistic effect of functional groups on chitosan-based adsorbent	46:116	Enhanced performance in uranium extraction by the synergistic effect of functional groups on chitosan-based adsorbent.					
36372493	4	1	from	effect	777:782	arg1	uranium					804:810	uranium	804:810	uranium	804:810	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	1	2	theme	sponge	142:147	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	2	theme	sponge	142:147	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	0	3	theme	functional	72:81	arg1	groups					83:88	functional groups	72:88	functional groups	72:88	Enhanced performance in uranium extraction by the synergistic effect of functional groups on chitosan-based adsorbent.					
36372493	4	4	theme	uranium	859:865	arg1	coefficients					843:854	the distribution coefficients	826:854	the distribution coefficients of uranium and vanadium	826:878	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	1	5	theme	phosphoric	149:158	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	5	theme	phosphoric	149:158	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	4	6	theme	group	736:740	arg1	introduction					706:717	the introduction	702:717	the introduction of the phosphate group	702:740	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	1	7	theme	chlorella	253:261	arg1	charcoal					276:283	chlorella hydrothermal charcoal	253:283	chlorella hydrothermal charcoal	253:283	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	4	8	theme	phosphate	726:734	arg1	group					736:740	the phosphate group	722:740	the phosphate group	722:740	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	3	9	theme	adsorption	542:551	arg1	studies					553:559	the adsorption studies	538:559	the adsorption studies of simulated seawater	538:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	3	10	from	selectivity	511:521	arg1	studies					553:559	the adsorption studies	538:559	the adsorption studies of simulated seawater	538:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	2	11	theme	Kinetics	286:293	arg1	experiments					314:324	Kinetics and thermodynamics experiments	286:324	Kinetics and thermodynamics experiments	286:324	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	1	12	theme	hydrothermal	263:274	arg1	charcoal					276:283	chlorella hydrothermal charcoal	253:283	chlorella hydrothermal charcoal	253:283	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	4	13	theme	distribution	830:841	arg1	coefficients					843:854	the distribution coefficients	826:854	the distribution coefficients of uranium and vanadium	826:878	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	4	14	theme	adsorption	766:775	arg1	effect					777:782	the adsorption effect	762:782	the adsorption effect of the adsorbent on uranium	762:810	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	1	15	theme	acid	160:163	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	15	theme	acid	160:163	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	5	16	theme	same	915:918	arg1	time					920:923	the same time	911:923	the same time	911:923	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	1	17	theme	functionalized	165:178	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	17	theme	functionalized	165:178	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	4	18	dep	adsorption	679:688	arg1	VI					675:676	VI	675:676	VI	675:676	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	3	19	theme	simulated	564:572	arg1	seawater					574:581	simulated seawater	564:581	simulated seawater	564:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	5	20	contain	has	933:935	arg2	performance					952:962	good recycling performance	937:962	good recycling performance	937:962	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	5	20	contain	has	933:935	arg1	SPCCHC					926:931	SPCCHC	926:931	SPCCHC	926:931	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	1	21	theme	porous	180:185	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	21	theme	porous	180:185	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	3	22	theme	seawater	574:581	arg1	studies					553:559	the adsorption studies	538:559	the adsorption studies of simulated seawater	538:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	4	23	theme	U	673:673	arg1	adsorption					679:688	U(VI) adsorption	673:688	U(VI) adsorption	673:688	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	0	24	theme	uranium	24:30	arg1	extraction					32:41	uranium extraction	24:41	uranium extraction	24:41	Enhanced performance in uranium extraction by the synergistic effect of functional groups on chitosan-based adsorbent.					
36372493	3	25	theme	mixed	589:593	arg1	solution					595:602	a mixed solution	587:602	a mixed solution of uranium-vanadium	587:622	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	1	26	theme	adsorbent	197:205	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	26	theme	adsorbent	197:205	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	5	27	theme	recycling	942:950	arg1	performance					952:962	good recycling performance	937:962	good recycling performance	937:962	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	2	28	theme	thermodynamics	299:312	arg1	experiments					314:324	Kinetics and thermodynamics experiments	286:324	Kinetics and thermodynamics experiments	286:324	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	29	theme	exothermic	460:469	arg1	reaction					471:478	a spontaneous exothermic reaction	446:478	a spontaneous exothermic reaction	446:478	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	30	dep	579.27 mg/g	404:414	arg1	288 K					417:421	288 K	417:421	288 K	417:421	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	3	31	from	solution	595:602	arg1	studies					553:559	the adsorption studies	538:559	the adsorption studies of simulated seawater	538:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	1	32	theme	named	208:212	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	32	theme	named	208:212	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	2	33	theme	spontaneous	448:458	arg1	reaction					471:478	a spontaneous exothermic reaction	446:478	a spontaneous exothermic reaction	446:478	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	34	theme	pH = 6.5	424:431	arg1	288 K					417:421	288 K	417:421	288 K	417:421	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	5	35	used	used	989:992	arg2	which					965:969	which	965:969	which	965:969	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	4	36	theme	SPCCHC	649:654	arg1	characterization					629:644	The characterization	625:644	The characterization of SPCCHC before and after U(VI) adsorption	625:688	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	0	37	theme	synergistic	50:60	arg1	effect					62:67	the synergistic effect	46:67	the synergistic effect of functional groups on chitosan-based adsorbent	46:116	Enhanced performance in uranium extraction by the synergistic effect of functional groups on chitosan-based adsorbent.					
36372493	3	38	theme	good	495:498	arg1	selectivity					511:521	good adsorption selectivity	495:521	good adsorption selectivity for uranium in the adsorption studies of simulated seawater	495:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	0	39	from	effect	62:67	arg1	adsorbent					108:116	adsorbent	108:116	adsorbent	108:116	Enhanced performance in uranium extraction by the synergistic effect of functional groups on chitosan-based adsorbent.					
36372493	5	40	theme	good	937:940	arg1	performance					952:962	good recycling performance	937:962	good recycling performance	937:962	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	2	41	theme	adsorption	362:371	arg1	579.27 mg/g					404:414	579.27 mg/g	404:414	579.27 mg/g (288 K, pH = 6.5)	404:432	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	41	theme	adsorption	362:371	arg1	capacity					373:380	the theoretical maximum adsorption capacity	338:380	the theoretical maximum adsorption capacity of SPCCHC to U(VI)	338:399	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	5	42	theme	natural	997:1003	arg1	extraction					1022:1031	natural seawater uranium extraction	997:1031	natural seawater uranium extraction	997:1031	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	3	43	theme	adsorption	500:509	arg1	selectivity					511:521	good adsorption selectivity	495:521	good adsorption selectivity for uranium in the adsorption studies of simulated seawater	495:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	2	44	theme	maximum	354:360	arg1	579.27 mg/g					404:414	579.27 mg/g	404:414	579.27 mg/g (288 K, pH = 6.5)	404:432	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	44	theme	maximum	354:360	arg1	capacity					373:380	the theoretical maximum adsorption capacity	338:380	the theoretical maximum adsorption capacity of SPCCHC to U(VI)	338:399	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	5	45	theme	seawater	1005:1012	arg1	extraction					1022:1031	natural seawater uranium extraction	997:1031	natural seawater uranium extraction	997:1031	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	2	46	theme	theoretical	342:352	arg1	579.27 mg/g					404:414	579.27 mg/g	404:414	579.27 mg/g (288 K, pH = 6.5)	404:432	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	46	theme	theoretical	342:352	arg1	capacity					373:380	the theoretical maximum adsorption capacity	338:380	the theoretical maximum adsorption capacity of SPCCHC to U(VI)	338:399	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	5	47	theme	uranium	1014:1020	arg1	extraction					1022:1031	natural seawater uranium extraction	997:1031	natural seawater uranium extraction	997:1031	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	2	48	dep	U	395:395	arg1	VI					397:398	VI	397:398	VI	397:398	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	1	49	theme	novel	136:140	arg1	composite					187:195	a novel sponge phosphoric acid functionalized porous composite adsorbent	134:205	a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC)	134:220	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	1	49	theme	novel	136:140	arg1	SPCCHC					214:219	named SPCCHC	208:219	named SPCCHC	208:219	In this study, a novel sponge phosphoric acid functionalized porous composite adsorbent (named SPCCHC) was prepared from chitosan and chlorella hydrothermal charcoal.					
36372493	4	50	theme	vanadium	871:878	arg1	coefficients					843:854	the distribution coefficients	826:854	the distribution coefficients of uranium and vanadium	826:878	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	5	51	dep	has	933:935	arg1	expected					974:981	expected	974:981	is expected to be used in natural seawater uranium extraction	971:1031	At the same time, SPCCHC has good recycling performance, which is expected to be used in natural seawater uranium extraction.					
36372493	4	52	dep	89.5	896:899	arg1	to					893:894	to	893:894	to	893:894	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	4	53	theme	adsorbent	791:799	arg1	effect					777:782	the adsorption effect	762:782	the adsorption effect of the adsorbent on uranium	762:810	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	4	54	dep	improve	754:760	arg1	differ					880:885	differ	880:885	differ by up to 89.5 times	880:905	The characterization of SPCCHC before and after U(VI) adsorption proves that the introduction of the phosphate group can greatly improve the adsorption effect of the adsorbent on uranium, particularly the distribution coefficients of uranium and vanadium differ by up to 89.5 times.					
36372493	3	55	theme	uranium-vanadium	607:622	arg1	solution					595:602	a mixed solution	587:602	a mixed solution of uranium-vanadium	587:622	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	3	55	theme	uranium-vanadium	607:622	arg1	selectivity					511:521	good adsorption selectivity	495:521	good adsorption selectivity for uranium in the adsorption studies of simulated seawater	495:581	SPCCHC showed good adsorption selectivity for uranium in the adsorption studies of simulated seawater and a mixed solution of uranium-vanadium.					
36372493	2	56	theme	SPCCHC	385:390	arg1	579.27 mg/g					404:414	579.27 mg/g	404:414	579.27 mg/g (288 K, pH = 6.5)	404:432	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36372493	2	56	theme	SPCCHC	385:390	arg1	capacity					373:380	the theoretical maximum adsorption capacity	338:380	the theoretical maximum adsorption capacity of SPCCHC to U(VI)	338:399	Kinetics and thermodynamics experiments showed that the theoretical maximum adsorption capacity of SPCCHC to U(VI) is 579.27 mg/g (288 K, pH = 6.5), indicating a spontaneous exothermic reaction.					
36876807	4	0	theme	core-shell	510:519	arg1	structures					521:530	core-shell structures	510:530	core-shell structures	510:530	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	9	1	theme	mechanical	1126:1135	arg1	support					1137:1143	mechanical support	1126:1143	mechanical support for NP repair	1126:1157	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	8	2	theme	signal	937:942	arg1	intensities					944:954	MRI signal intensities	933:954	MRI signal intensities	933:954	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	7	3	theme	excellent	798:806	arg1	strength					820:827	excellent compressive strength	798:827	excellent compressive strength	798:827	The composite hydrogel exhibited excellent compressive strength and enabled leak-proof delivery of PRP.					
36876807	2	4	theme	load-bearing	300:311	arg1	implants					313:320	load-bearing implants	300:320	load-bearing implants	300:320	However, the pressure within the intervertebral disc requires load-bearing implants.					
36876807	8	5	theme	MRI	933:935	arg1	intensities					944:954	MRI signal intensities	933:954	MRI signal intensities	933:954	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	7	6	theme	composite	769:777	arg1	hydrogel					779:786	The composite hydrogel	765:786	The composite hydrogel	765:786	The composite hydrogel exhibited excellent compressive strength and enabled leak-proof delivery of PRP.					
36876807	0	7	theme	nucleus	92:98	arg1	pulposus					100:107	nucleus pulposus	92:107	nucleus pulposus	92:107	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	4	8	theme	fibroin	486:492	arg1	nanofibers					494:503	silk fibroin nanofibers	481:503	silk fibroin nanofibers with core-shell structures	481:530	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	8	9	theme	rat	872:874	arg1	models					909:914	rat intervertebral disc degeneration models	872:914	rat intervertebral disc degeneration models	872:914	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	3	10	theme	phase	357:361	arg1	transition					363:372	a rapid phase transition	349:372	a rapid phase transition	349:372	The hydrogel must undergo a rapid phase transition upon injection to avoid leakage.					
36876807	4	11	theme	silk	481:484	arg1	nanofibers					494:503	silk fibroin nanofibers	481:503	silk fibroin nanofibers with core-shell structures	481:530	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	8	12	with	injections	1000:1009	arg1	hydrogel					1041:1048	the nanofiber-reinforced hydrogel	1016:1048	the nanofiber-reinforced hydrogel	1016:1048	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	9	13	theme	fiber	1066:1070	arg1	structure					1081:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	2	14	theme	intervertebral	271:284	arg1	disc					286:289	the intervertebral disc	267:289	the intervertebral disc	267:289	However, the pressure within the intervertebral disc requires load-bearing implants.					
36876807	9	15	theme	biomimetic	1055:1064	arg1	structure					1081:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	9	16	theme	gel-like	1072:1079	arg1	structure					1081:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure	1051:1089	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	8	17	theme	intervertebral	876:889	arg1	models					909:914	rat intervertebral disc degeneration models	872:914	rat intervertebral disc degeneration models	872:914	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	5	18	theme	cell	618:621	arg1	proliferation					623:635	cell proliferation	618:635	cell proliferation	618:635	The nanofiber-embedded hydrogel provided support to adjacent tissues and facilitated cell proliferation.					
36876807	6	19	theme	NP	748:749	arg1	regeneration					751:762	enhanced NP regeneration	739:762	enhanced NP regeneration	739:762	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	6	20	theme	enhanced	739:746	arg1	regeneration					751:762	enhanced NP regeneration	739:762	enhanced NP regeneration	739:762	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	9	21	theme	NP	1263:1264	arg1	regeneration					1247:1258	the regeneration	1243:1258	the regeneration of NP	1243:1264	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	0	22	theme	alginate	21:28	arg1	hydrogel					30:37	alginate hydrogel	21:37	alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus	21:107	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	1	23	theme	Injectable	110:119	arg1	hydrogels					121:129	Injectable hydrogels	110:129	Injectable hydrogels	110:129	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	8	24	theme	injections	1000:1009	arg1	8 weeks					989:995	8 weeks	989:995	8 weeks of injections with the nanofiber-reinforced hydrogel	989:1048	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	9	25	theme	microenvironment	1203:1218	arg1	reconstruction					1174:1187	the reconstruction	1170:1187	the reconstruction of the tissue microenvironment	1170:1218	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	0	26	theme	leak-proof	43:52	arg1	delivery					54:61	leak-proof delivery	43:61	leak-proof delivery	43:61	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	6	27	theme	sustained	717:725	arg1	release					727:733	sustained release	717:733	sustained release	717:733	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	1	28	theme	in	212:213	arg1	microenvironment					220:235	the in vivo microenvironment	208:235	the in vivo microenvironment	208:235	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	9	29	theme	tissue	1196:1201	arg1	microenvironment					1203:1218	the tissue microenvironment	1192:1218	the tissue microenvironment	1192:1218	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	7	30	theme	PRP	864:866	arg1	delivery					852:859	leak-proof delivery	841:859	leak-proof delivery of PRP	841:866	The composite hydrogel exhibited excellent compressive strength and enabled leak-proof delivery of PRP.					
36876807	0	31	theme	higher	67:72	arg1	loading					81:87	higher stress loading	67:87	higher stress loading	67:87	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	5	32	theme	adjacent	585:592	arg1	tissues					594:600	adjacent tissues	585:600	adjacent tissues	585:600	The nanofiber-embedded hydrogel provided support to adjacent tissues and facilitated cell proliferation.					
36876807	7	33	theme	leak-proof	841:850	arg1	delivery					852:859	leak-proof delivery	841:859	leak-proof delivery of PRP	841:866	The composite hydrogel exhibited excellent compressive strength and enabled leak-proof delivery of PRP.					
36876807	4	34	theme	injectable	425:434	arg1	hydrogel					452:459	an injectable sodium alginate hydrogel	422:459	an injectable sodium alginate hydrogel	422:459	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	8	35	theme	degeneration	896:907	arg1	models					909:914	rat intervertebral disc degeneration models	872:914	rat intervertebral disc degeneration models	872:914	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	1	36	dep	in	212:213	arg1	vivo					215:218	vivo	215:218	vivo	215:218	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	8	37	theme	nanofiber-reinforced	1020:1039	arg1	hydrogel					1041:1048	the nanofiber-reinforced hydrogel	1016:1048	the nanofiber-reinforced hydrogel	1016:1048	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	8	38	theme	disc	891:894	arg1	models					909:914	rat intervertebral disc degeneration models	872:914	rat intervertebral disc degeneration models	872:914	In rat intervertebral disc degeneration models, radiography and MRI signal intensities were significantly reduced after 8 weeks of injections with the nanofiber-reinforced hydrogel.					
36876807	4	39	theme	alginate	443:450	arg1	hydrogel					452:459	an injectable sodium alginate hydrogel	422:459	an injectable sodium alginate hydrogel	422:459	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	5	40	theme	nanofiber-embedded	537:554	arg1	hydrogel					556:563	The nanofiber-embedded hydrogel	533:563	The nanofiber-embedded hydrogel	533:563	The nanofiber-embedded hydrogel provided support to adjacent tissues and facilitated cell proliferation.					
36876807	1	41	theme	degenerative	151:162	arg1	pulposus					172:179	degenerative nucleus pulposus	151:179	degenerative nucleus pulposus (NP)	151:184	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	1	41	theme	degenerative	151:162	arg1	NP					182:183	NP	182:183	NP	182:183	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	6	42	theme	core-shell	691:700	arg1	nanofibers					702:711	the core-shell nanofibers	687:711	the core-shell nanofibers for sustained release and enhanced NP regeneration	687:762	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	0	43	theme	stress	74:79	arg1	loading					81:87	higher stress loading	67:87	higher stress loading	67:87	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	4	44	theme	sodium	436:441	arg1	hydrogel					452:459	an injectable sodium alginate hydrogel	422:459	an injectable sodium alginate hydrogel	422:459	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36876807	1	45	theme	nucleus	164:170	arg1	pulposus					172:179	degenerative nucleus pulposus	151:179	degenerative nucleus pulposus (NP)	151:184	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	1	45	theme	nucleus	164:170	arg1	NP					182:183	NP	182:183	NP	182:183	Injectable hydrogels effectively remodel degenerative nucleus pulposus (NP) with a resemblance to the in vivo microenvironment.					
36876807	9	46	theme	NP	1149:1150	arg1	repair					1152:1157	NP repair	1149:1157	NP repair	1149:1157	The biomimetic fiber gel-like structure was constructed in situ, providing mechanical support for NP repair, promoting the reconstruction of the tissue microenvironment, and finally realizing the regeneration of NP.					
36876807	7	47	theme	compressive	808:818	arg1	strength					820:827	excellent compressive strength	798:827	excellent compressive strength	798:827	The composite hydrogel exhibited excellent compressive strength and enabled leak-proof delivery of PRP.					
36876807	3	48	theme	rapid	351:355	arg1	transition					363:372	a rapid phase transition	349:372	a rapid phase transition	349:372	The hydrogel must undergo a rapid phase transition upon injection to avoid leakage.					
36876807	0	49	from	hydrogel	30:37	arg1	pulposus					100:107	nucleus pulposus	92:107	nucleus pulposus	92:107	Nanofiber reinforced alginate hydrogel for leak-proof delivery and higher stress loading in nucleus pulposus.					
36876807	6	50	theme	Platelet-rich	638:650	arg1	plasma					652:657	Platelet-rich plasma	638:657	Platelet-rich plasma (PRP)	638:663	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	6	50	theme	Platelet-rich	638:650	arg1	PRP					660:662	PRP	660:662	PRP	660:662	Platelet-rich plasma (PRP) was incorporated into the core-shell nanofibers for sustained release and enhanced NP regeneration.					
36876807	4	51	with	nanofibers	494:503	arg1	structures					521:530	core-shell structures	510:530	core-shell structures	510:530	In this study, an injectable sodium alginate hydrogel was reinforced with silk fibroin nanofibers with core-shell structures.					
36087967	1	0	with	bio-adhesive	249:260	arg1	properties					286:295	excellent adhesion properties	267:295	excellent adhesion properties	267:295	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	1	0	with	bio-adhesive	249:260	arg1	resistance					305:314	mildew resistance	298:314	mildew resistance	298:314	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	1	0	with	bio-adhesive	249:260	arg1	activity					335:342	antibacterial activity	321:342	antibacterial activity	321:342	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	3	1	theme	in-situ	595:601	arg1	biomineralization					603:619	the in-situ biomineralization	591:619	the in-situ biomineralization of inorganic nanoparticles	591:646	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	1	2	theme	adhesion	277:284	arg1	properties					286:295	excellent adhesion properties	267:295	excellent adhesion properties	267:295	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	6	3	theme	anti-mildew	1201:1211	arg1	result					1056:1061	a result	1054:1061	a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1054:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	6	3	theme	anti-mildew	1201:1211	arg1	properties					1232:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	3	4	theme	optimized	669:677	arg1	framework					712:720	an optimized organic-inorganic mineralization framework	666:720	an optimized organic-inorganic mineralization framework in the polymer	666:735	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	3	5	theme	organic-inorganic	679:695	arg1	framework					712:720	an optimized organic-inorganic mineralization framework	666:720	an optimized organic-inorganic mineralization framework in the polymer	666:735	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	4	6	theme	covalent	919:926	arg1	bonds					928:932	dynamic covalent bonds	911:932	dynamic covalent bonds	911:932	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	4	7	theme	sacrificial	851:861	arg1	bonds					872:876	sacrificial hydrogen bonds	851:876	sacrificial hydrogen bonds	851:876	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	1	8	theme	mildew	298:303	arg1	resistance					305:314	mildew resistance	298:314	mildew resistance	298:314	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	6	9	theme	favorable	1191:1199	arg1	result					1056:1061	a result	1054:1061	a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1054:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	6	9	theme	favorable	1191:1199	arg1	properties					1232:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	1	10	dep	chemistry	140:148	arg1	the					123:125	the	123:125	the	123:125	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	3	11	theme	cellulose	497:505	arg1	nanocrystals					507:518	The biomineralized cellulose nanocrystals	478:518	The biomineralized cellulose nanocrystals	478:518	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	2	12	theme	base	462:465	arg1	reactions					467:475	grafting and Schiff base reactions	442:475	grafting and Schiff base reactions	442:475	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	6	13	theme	ε-polylysine	1125:1136	arg1	effect					1082:1087	the synergistic effect	1066:1087	the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1066:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	6	14	theme	aldehyde	1143:1150	arg1	group					1152:1156	aldehyde group	1143:1156	aldehyde group	1143:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	5	15	theme	adhesive	974:981	arg1	strength					948:955	The adhesion strength	935:955	The adhesion strength of the composite adhesive	935:981	The adhesion strength of the composite adhesive reached 1.13 MPa, which was 151% higher than the pristine adhesive.					
36087967	2	16	theme	Schiff	455:460	arg1	base					462:465	Schiff base	455:465	Schiff base	455:465	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	0	17	theme	phenol-amine	12:23	arg1	chemistry					25:33	Bioinspired phenol-amine chemistry	0:33	Bioinspired phenol-amine chemistry for developing bioadhesives	0:61	Bioinspired phenol-amine chemistry for developing bioadhesives based on biomineralized cellulose nanocrystals.					
36087967	6	18	theme	catechol	1096:1103	arg1	component					1105:1113	the catechol component	1092:1113	the catechol component	1092:1113	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	2	19	theme	biomimetic	350:359	arg1	strategy					361:368	This biomimetic strategy	345:368	This biomimetic strategy	345:368	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	6	20	theme	anti-bacterial	1217:1230	arg1	result					1056:1061	a result	1054:1061	a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1054:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	6	20	theme	anti-bacterial	1217:1230	arg1	properties					1232:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	1	21	theme	green	207:211	arg1	strategy					224:231	a green and facile strategy	205:231	a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity	205:342	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	0	22	theme	Bioinspired	0:10	arg1	chemistry					25:33	Bioinspired phenol-amine chemistry	0:33	Bioinspired phenol-amine chemistry for developing bioadhesives	0:61	Bioinspired phenol-amine chemistry for developing bioadhesives based on biomineralized cellulose nanocrystals.					
36087967	6	23	theme	cationic	1116:1123	arg1	ε-polylysine					1125:1136	cationic ε-polylysine	1116:1136	cationic ε-polylysine	1116:1136	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	3	24	theme	mineralization	697:710	arg1	framework					712:720	an optimized organic-inorganic mineralization framework	666:720	an optimized organic-inorganic mineralization framework in the polymer	666:735	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	3	25	from	framework	712:720	arg1	polymer					729:735	the polymer	725:735	the polymer	725:735	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	2	26	theme	grafting	442:449	arg1	reactions					467:475	grafting and Schiff base reactions	442:475	grafting and Schiff base reactions	442:475	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	4	27	theme	dynamic	911:917	arg1	bonds					928:932	dynamic covalent bonds	911:932	dynamic covalent bonds	911:932	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	1	28	theme	facile	217:222	arg1	strategy					224:231	a green and facile strategy	205:231	a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity	205:342	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	6	29	theme	component	1105:1113	arg1	effect					1082:1087	the synergistic effect	1066:1087	the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1066:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	3	30	theme	nanoparticles	634:646	arg1	biomineralization					603:619	the in-situ biomineralization	591:619	the in-situ biomineralization of inorganic nanoparticles	591:646	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	1	31	theme	phenol-amine	127:138	arg1	chemistry					140:148	phenol-amine chemistry	127:148	phenol-amine chemistry	127:148	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	3	32	theme	nanocrystal	552:562	arg1	bio-template					564:575	a cellulose nanocrystal bio-template	540:575	a cellulose nanocrystal bio-template	540:575	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	5	33	theme	adhesion	939:946	arg1	strength					948:955	The adhesion strength	935:955	The adhesion strength of the composite adhesive	935:981	The adhesion strength of the composite adhesive reached 1.13 MPa, which was 151% higher than the pristine adhesive.					
36087967	1	34	theme	antibacterial	321:333	arg1	activity					335:342	antibacterial activity	321:342	antibacterial activity	321:342	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	0	35	theme	developing	39:48	arg1	bioadhesives					50:61	developing bioadhesives	39:61	developing bioadhesives	39:61	Bioinspired phenol-amine chemistry for developing bioadhesives based on biomineralized cellulose nanocrystals.					
36087967	3	36	theme	biomineralized	482:495	arg1	nanocrystals					507:518	The biomineralized cellulose nanocrystals	478:518	The biomineralized cellulose nanocrystals	478:518	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	4	37	theme	hydrogen	863:870	arg1	bonds					872:876	sacrificial hydrogen bonds	851:876	sacrificial hydrogen bonds	851:876	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	6	38	theme	group	1152:1156	arg1	effect					1082:1087	the synergistic effect	1066:1087	the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1066:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	4	39	theme	adhesive	772:779	arg1	strength					750:757	The bonding strength	738:757	The bonding strength of composite adhesive	738:779	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	4	40	theme	multiple	811:818	arg1	networks					834:841	multiple cross-linking networks	811:841	multiple cross-linking networks	811:841	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	2	41	theme	catechol-modified	394:410	arg1	ε-polylysine					412:423	functional catechol-modified ε-polylysine	383:423	functional catechol-modified ε-polylysine	383:423	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	6	42	theme	effect	1082:1087	arg1	result					1056:1061	a result	1054:1061	a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1054:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	6	42	theme	effect	1082:1087	arg1	properties					1232:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	favorable anti-mildew and anti-bacterial properties	1191:1241	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	2	43	theme	functional	383:392	arg1	ε-polylysine					412:423	functional catechol-modified ε-polylysine	383:423	functional catechol-modified ε-polylysine	383:423	This biomimetic strategy incorporates functional catechol-modified ε-polylysine and vanillin via grafting and Schiff base reactions.					
36087967	6	44	theme	synergistic	1070:1080	arg1	effect					1082:1087	the synergistic effect	1066:1087	the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group	1066:1156	As a result of the synergistic effect of the catechol component, cationic ε-polylysine, and aldehyde group, the bio-adhesive also exhibited favorable anti-mildew and anti-bacterial properties.					
36087967	4	45	theme	cross-linking	820:832	arg1	networks					834:841	multiple cross-linking networks	811:841	multiple cross-linking networks	811:841	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	4	46	theme	electrostatic	879:891	arg1	interactions					893:904	electrostatic interactions	879:904	electrostatic interactions	879:904	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	3	47	theme	inorganic	624:632	arg1	nanoparticles					634:646	inorganic nanoparticles	624:646	inorganic nanoparticles	624:646	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	0	48	theme	cellulose	87:95	arg1	nanocrystals					97:108	biomineralized cellulose nanocrystals	72:108	biomineralized cellulose nanocrystals	72:108	Bioinspired phenol-amine chemistry for developing bioadhesives based on biomineralized cellulose nanocrystals.					
36087967	3	49	theme	cellulose	542:550	arg1	bio-template					564:575	a cellulose nanocrystal bio-template	540:575	a cellulose nanocrystal bio-template	540:575	The biomineralized cellulose nanocrystals were prepared using a cellulose nanocrystal bio-template by regulating the in-situ biomineralization of inorganic nanoparticles, thereby building an optimized organic-inorganic mineralization framework in the polymer.					
36087967	1	50	theme	insect	175:180	arg1	cuticles					182:189	insect cuticles	175:189	insect cuticles	175:189	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	0	51	theme	biomineralized	72:85	arg1	nanocrystals					97:108	biomineralized cellulose nanocrystals	72:108	biomineralized cellulose nanocrystals	72:108	Bioinspired phenol-amine chemistry for developing bioadhesives based on biomineralized cellulose nanocrystals.					
36087967	4	52	theme	bonding	742:748	arg1	strength					750:757	The bonding strength	738:757	The bonding strength of composite adhesive	738:779	The bonding strength of composite adhesive was significantly improved by multiple cross-linking networks through sacrificial hydrogen bonds, electrostatic interactions, and dynamic covalent bonds.					
36087967	1	53	theme	cuticles	182:189	arg1	biomineralization					154:170	biomineralization	154:170	biomineralization	154:170	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	1	53	theme	cuticles	182:189	arg1	chemistry					140:148	phenol-amine chemistry	127:148	phenol-amine chemistry	127:148	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
36087967	1	54	theme	excellent	267:275	arg1	properties					286:295	excellent adhesion properties	267:295	excellent adhesion properties	267:295	Inspired by the phenol-amine chemistry and biomineralization of insect cuticles, we developed a green and facile strategy for preparing a bio-adhesive with excellent adhesion properties, mildew resistance, and antibacterial activity.					
35550751	1	0	contain	containing	169:178	arg2	nanocrystals					211:222	cellulose nanocrystals	201:222	cellulose nanocrystals (CNC)	201:228	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	0	contain	containing	169:178	arg2	biopolymers					180:190	biopolymers	180:190	biopolymers	180:190	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	0	contain	containing	169:178	arg1	gels					164:167	stimuli-responsible electroactive gels	130:167	stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	130:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	0	contain	containing	169:178	arg2	CNC					225:227	CNC	225:227	CNC	225:227	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	0	1	theme	ion	105:107	arg1	gels					109:112	solvent electroactive ion gels	83:112	solvent electroactive ion gels	83:112	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	2	2	from	applications	339:350	arg1	materials					369:377	electroactive materials	355:377	electroactive materials	355:377	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	1	3	theme	cellulose	201:209	arg1	CNC					225:227	CNC	225:227	CNC	225:227	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	3	theme	cellulose	201:209	arg1	nanocrystals					211:222	cellulose nanocrystals	201:222	cellulose nanocrystals (CNC)	201:228	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	3	4	from	%	554:554	arg1	DES					580:582	polymerizable DES	566:582	polymerizable DES based on choline chloride/acrylic acid	566:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	6	5	theme	materials	947:955	arg1	application					919:929	The potential application	905:929	The potential application of the obtained materials for designing of a 3D-printed tactile sensor	905:1000	The potential application of the obtained materials for designing of a 3D-printed tactile sensor have been demonstrated.					
35550751	1	6	dep	such	193:196	arg1	as					198:199	as	198:199	as	198:199	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	5	7	from	effect	711:716	arg1	morphology					740:749	morphology	740:749	morphology	740:749	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	5	7	from	effect	711:716	arg1	conductivity					761:772	ionic conductivity	755:772	ionic conductivity	755:772	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	6	8	theme	obtained	938:945	arg1	materials					947:955	the obtained materials	934:955	the obtained materials	934:955	The potential application of the obtained materials for designing of a 3D-printed tactile sensor have been demonstrated.					
35550751	5	9	theme	ionic	755:759	arg1	conductivity					761:772	ionic conductivity	755:772	ionic conductivity	755:772	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	2	10	theme	electroactive	355:367	arg1	materials					369:377	electroactive materials	355:377	electroactive materials	355:377	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	2	11	theme	cellulose	408:416	arg1	processing					394:403	processing	394:403	processing of cellulose	394:416	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	5	12	theme	electroactive	788:800	arg1	gels					812:815	3D-printed electroactive composite gels	777:815	3D-printed electroactive composite gels	777:815	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	5	13	theme	3D-printed	777:786	arg1	gels					812:815	3D-printed electroactive composite gels	777:815	3D-printed electroactive composite gels	777:815	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	4	14	from	impact	628:633	arg1	3D-printability					676:690	3D-printability	676:690	3D-printability	676:690	The impact of rheological properties of the inks on 3D-printability was evaluated.					
35550751	3	15	theme	polymerizable	566:578	arg1	DES					580:582	polymerizable DES	566:582	polymerizable DES based on choline chloride/acrylic acid	566:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	0	16	theme	Rheological	0:10	arg1	properties					12:21	Rheological properties	0:21	Rheological properties	0:21	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	2	17	theme	potential	316:324	arg1	interest					326:333	a potential interest	314:333	a potential interest for applications in electroactive materials as well as for processing of cellulose	314:416	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	5	18	theme	atomic	840:845	arg1	microscopy					853:862	atomic force microscopy	840:862	atomic force microscopy	840:862	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	3	19	theme	CNC	559:561	arg1	%					554:554	6-15 wt%	547:554	6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid	547:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	3	19	theme	CNC	559:561	arg1	CNC					559:561	CNC	559:561	CNC in polymerizable DES based on choline chloride/acrylic acid	559:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	4	20	theme	rheological	638:648	arg1	properties					650:659	rheological properties	638:659	rheological properties of the inks	638:671	The impact of rheological properties of the inks on 3D-printability was evaluated.					
35550751	5	21	theme	force	847:851	arg1	microscopy					853:862	atomic force microscopy	840:862	atomic force microscopy	840:862	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	6	22	theme	potential	909:917	arg1	application					919:929	The potential application	905:929	The potential application of the obtained materials for designing of a 3D-printed tactile sensor	905:1000	The potential application of the obtained materials for designing of a 3D-printed tactile sensor have been demonstrated.					
35550751	1	23	theme	stimuli-responsible	130:148	arg1	gels					164:167	stimuli-responsible electroactive gels	130:167	stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	130:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	3	24	theme	processing	464:473	arg1	cellulose					492:500	processing microcrystalline cellulose	464:500	processing microcrystalline cellulose	464:500	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	0	25	theme	cellulose	46:54	arg1	nanocrystals/deep					56:72	cellulose nanocrystals/deep	46:72	cellulose nanocrystals/deep	46:72	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	5	26	theme	CNC	721:723	arg1	content					725:731	CNC content	721:731	CNC content	721:731	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	3	27	theme	choline	593:599	arg1	acid					618:621	choline chloride/acrylic acid	593:621	choline chloride/acrylic acid	593:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	5	28	theme	impedance	868:876	arg1	measurements					891:902	impedance spectroscopy measurements	868:902	impedance spectroscopy measurements	868:902	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	4	29	theme	inks	668:671	arg1	properties					650:659	rheological properties	638:659	rheological properties of the inks	638:671	The impact of rheological properties of the inks on 3D-printability was evaluated.					
35550751	5	30	theme	content	725:731	arg1	effect					711:716	The effect	707:716	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels	707:815	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	5	31	theme	composite	802:810	arg1	gels					812:815	3D-printed electroactive composite gels	777:815	3D-printed electroactive composite gels	777:815	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	3	32	theme	chloride/acrylic	601:616	arg1	acid					618:621	choline chloride/acrylic acid	593:621	choline chloride/acrylic acid	593:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	5	33	theme	spectroscopy	878:889	arg1	measurements					891:902	impedance spectroscopy measurements	868:902	impedance spectroscopy measurements	868:902	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	1	34	theme	prospective	236:246	arg1	3D-printing					115:125	3D-printing	115:125	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	115:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	34	theme	prospective	236:246	arg1	area					248:251	a prospective area	234:251	a prospective area of material science	234:271	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	5	35	theme	gels	812:815	arg1	morphology					740:749	morphology	740:749	morphology	740:749	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	5	35	theme	gels	812:815	arg1	conductivity					761:772	ionic conductivity	755:772	ionic conductivity	755:772	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	3	36	contain	containing	536:545	arg2	%					554:554	6-15 wt%	547:554	6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid	547:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	3	36	contain	containing	536:545	arg2	CNC					559:561	CNC	559:561	CNC in polymerizable DES based on choline chloride/acrylic acid	559:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	3	36	contain	containing	536:545	arg1	inks					531:534	inks	531:534	inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid	531:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	5	37	dep	morphology	740:749	arg1	the					736:738	the	736:738	the	736:738	The effect of CNC content on the morphology and ionic conductivity of 3D-printed electroactive composite gels was investigated using atomic force microscopy and impedance spectroscopy measurements.					
35550751	3	38	used	used	507:510	arg2	CNC					433:435	CNC	433:435	CNC obtained by two methods of processing microcrystalline cellulose	433:500	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	1	39	theme	electroactive	150:162	arg1	gels					164:167	stimuli-responsible electroactive gels	130:167	stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	130:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	0	40	theme	nanocrystals/deep	56:72	arg1	3D-printability					27:41	3D-printability	27:41	3D-printability	27:41	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	0	40	theme	nanocrystals/deep	56:72	arg1	properties					12:21	Rheological properties	0:21	Rheological properties	0:21	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	6	41	theme	3D-printed	976:985	arg1	sensor					995:1000	a 3D-printed tactile sensor	974:1000	a 3D-printed tactile sensor	974:1000	The potential application of the obtained materials for designing of a 3D-printed tactile sensor have been demonstrated.					
35550751	1	42	theme	gels	164:167	arg1	3D-printing					115:125	3D-printing	115:125	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	115:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	42	theme	gels	164:167	arg1	area					248:251	a prospective area	234:251	a prospective area of material science	234:271	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	3	43	from	CNC	559:561	arg1	DES					580:582	polymerizable DES	566:582	polymerizable DES based on choline chloride/acrylic acid	566:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	3	44	theme	microcrystalline	475:490	arg1	cellulose					492:500	processing microcrystalline cellulose	464:500	processing microcrystalline cellulose	464:500	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	2	45	theme	eutectic	279:286	arg1	DES					298:300	DES	298:300	DES	298:300	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	2	45	theme	eutectic	279:286	arg1	solvents					288:295	Deep eutectic solvents	274:295	Deep eutectic solvents (DES)	274:301	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	3	46	theme	cellulose	492:500	arg1	methods					453:459	two methods	449:459	two methods of processing microcrystalline cellulose	449:500	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	0	47	theme	electroactive	91:103	arg1	gels					109:112	solvent electroactive ion gels	83:112	solvent electroactive ion gels	83:112	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	4	48	theme	properties	650:659	arg1	impact					628:633	The impact	624:633	The impact of rheological properties of the inks on 3D-printability	624:690	The impact of rheological properties of the inks on 3D-printability was evaluated.					
35550751	2	49	theme	Deep	274:277	arg1	DES					298:300	DES	298:300	DES	298:300	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	2	49	theme	Deep	274:277	arg1	solvents					288:295	Deep eutectic solvents	274:295	Deep eutectic solvents (DES)	274:301	Deep eutectic solvents (DES) have shown a potential interest for applications in electroactive materials as well as for processing of cellulose.					
35550751	3	50	from	DES	580:582	arg1	%					554:554	6-15 wt%	547:554	6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid	547:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	3	50	from	DES	580:582	arg1	CNC					559:561	CNC	559:561	CNC in polymerizable DES based on choline chloride/acrylic acid	559:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	0	51	theme	solvent	83:89	arg1	gels					109:112	solvent electroactive ion gels	83:112	solvent electroactive ion gels	83:112	Rheological properties and 3D-printability of cellulose nanocrystals/deep eutectic solvent electroactive ion gels.					
35550751	3	52	theme	inks	531:534	arg1	preparation					516:526	preparation	516:526	preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid	516:621	In this work, CNC obtained by two methods of processing microcrystalline cellulose were used for preparation of inks containing 6-15 wt% of CNC in polymerizable DES based on choline chloride/acrylic acid.					
35550751	6	53	theme	tactile	987:993	arg1	sensor					995:1000	a 3D-printed tactile sensor	974:1000	a 3D-printed tactile sensor	974:1000	The potential application of the obtained materials for designing of a 3D-printed tactile sensor have been demonstrated.					
35550751	1	54	theme	science	265:271	arg1	3D-printing					115:125	3D-printing	115:125	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC),	115:229	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
35550751	1	54	theme	science	265:271	arg1	area					248:251	a prospective area	234:251	a prospective area of material science	234:271	3D-printing of stimuli-responsible electroactive gels containing biopolymers, such as cellulose nanocrystals (CNC), is a prospective area of material science.					
36080153	5	0	from	LFK	772:774	arg1	share					748:752	A substantial share	734:752	A substantial share of acetic acid in LFK	734:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	7	1	theme	subjects	1117:1124	arg1	%					1104:1104	63%	1102:1104	63% of elderly subjects	1102:1124	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	1	theme	subjects	1117:1124	arg1	subjects					1117:1124	elderly subjects	1109:1124	elderly subjects	1109:1124	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	1	2	theme	unique	230:235	arg1	composition					246:256	its unique chemical composition	226:256	its unique chemical composition	226:256	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	8	3	theme	right	1325:1329	arg1	acidity					1173:1179	The lower acidity	1163:1179	The lower acidity	1163:1179	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	3	theme	right	1325:1329	arg1	"					1330:1330	"just about right"	1313:1330	"just about right" in JAR scale	1313:1343	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	7	4	theme	galactose	1037:1045	arg1	galactose					1037:1045	galactose	1037:1045	galactose	1037:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	4	theme	galactose	1037:1045	arg1	glucose					1025:1031	glucose	1025:1031	glucose	1025:1031	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	4	theme	galactose	1037:1045	arg1	amounts					1014:1020	higher amounts	1007:1020	higher amounts of glucose and galactose	1007:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	1	5	from	diet	149:152	arg1	crucial					134:140	crucial	134:140	crucial	134:140	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	2	6	theme	compound	340:347	arg1	profile					349:355	the volatile compound profile	327:355	the volatile compound profile	327:355	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	1	7	theme	chemical	237:244	arg1	composition					246:256	its unique chemical composition	226:256	its unique chemical composition	226:256	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	0	8	theme	Elderly	89:95	arg1	Consumers					97:105	Elderly Consumers	89:105	Elderly Consumers	89:105	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	5	9	from	acid	764:767	arg1	LFK					772:774	LFK	772:774	LFK	772:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	3	10	theme	hedonic	515:521	arg1	acceptability					523:535	hedonic acceptability	515:535	hedonic acceptability of LFK	515:542	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	4	11	theme	aroma	727:731	arg1	intensity					707:715	the high intensity	698:715	the high intensity of creamy aroma	698:731	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	7	12	from	due	1000:1002	arg1	TK					1055:1056	TK	1055:1056	TK	1055:1056	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	3	13	theme	acceptability	523:535	arg1	perception					473:482	The perception	469:482	The perception of main sensory attributes and hedonic acceptability of LFK by elderly	469:553	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	1	14	dep	crucial	134:140	arg1	kefir					213:217	kefir	213:217	kefir	213:217	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	7	15	theme	JAR	1151:1153	arg1	scale					1156:1160	the just-about-right (JAR) scale	1129:1160	the just-about-right (JAR) scale	1129:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	2	16	theme	volatile	331:338	arg1	profile					349:355	the volatile compound profile	327:355	the volatile compound profile	327:355	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	3	17	theme	attributes	500:509	arg1	perception					473:482	The perception	469:482	The perception of main sensory attributes and hedonic acceptability of LFK by elderly	469:553	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	1	18	theme	consumers	184:192	arg1	diet					149:152	the diet	145:152	the diet of lactose-intolerant elderly consumers	145:192	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	1	19	theme	lactose-intolerant	157:174	arg1	consumers					184:192	lactose-intolerant elderly consumers	157:192	lactose-intolerant elderly consumers	157:192	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	7	20	theme	right	1092:1096	arg1	"					1097:1097	"just about right"	1080:1097	"just about right" by 63% of elderly subjects in the just-about-right (JAR) scale	1080:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	20	theme	right	1092:1096	arg1	taste					983:987	The intense sweet taste	965:987	The intense sweet taste of LFK	965:994	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	5	21	theme	creamy	859:864	arg1	aroma					866:870	the creamy aroma	855:870	the creamy aroma	855:870	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	7	22	theme	glucose	1025:1031	arg1	galactose					1037:1045	galactose	1037:1045	galactose	1037:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	22	theme	glucose	1025:1031	arg1	glucose					1025:1031	glucose	1025:1031	glucose	1025:1031	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	22	theme	glucose	1025:1031	arg1	amounts					1014:1020	higher amounts	1007:1020	higher amounts of glucose and galactose	1007:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	1	23	theme	elderly	176:182	arg1	consumers					184:192	lactose-intolerant elderly consumers	157:192	lactose-intolerant elderly consumers	157:192	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	7	24	theme	higher	1007:1012	arg1	galactose					1037:1045	galactose	1037:1045	galactose	1037:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	24	theme	higher	1007:1012	arg1	glucose					1025:1031	glucose	1025:1031	glucose	1025:1031	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	24	theme	higher	1007:1012	arg1	amounts					1014:1020	higher amounts	1007:1020	higher amounts of glucose and galactose	1007:1045	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	1	25	from	crucial	134:140	arg1	diet					149:152	the diet	145:152	the diet of lactose-intolerant elderly consumers	145:192	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	4	26	theme	creamy	720:725	arg1	aroma					727:731	creamy aroma	720:731	creamy aroma	720:731	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	2	27	theme	sensory	379:385	arg1	attributes					387:396	the corresponding sensory attributes	361:396	the corresponding sensory attributes	361:396	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	0	28	theme	Volatile	0:7	arg1	Composition					9:19	Volatile Composition	0:19	Volatile Composition	0:19	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	2	29	theme	corresponding	365:377	arg1	attributes					387:396	the corresponding sensory attributes	361:396	the corresponding sensory attributes	361:396	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	0	30	theme	Sensory	25:31	arg1	Profile					33:39	Sensory Profile	25:39	Sensory Profile	25:39	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	8	31	theme	elderly	1293:1299	arg1	subjects					1301:1308	elderly subjects	1293:1308	elderly subjects	1293:1308	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	9	32	theme	lactose-free	1397:1408	arg1	kefir					1410:1414	the lactose-free kefir	1393:1414	the lactose-free kefir by elderly subjects	1393:1434	These two taste attributes dominated in liking the lactose-free kefir by elderly subjects.					
36080153	5	33	theme	high	800:803	arg1	intensity					805:813	high intensity	800:813	high intensity of sour aroma	800:827	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	1	34	theme	valuable	275:282	arg1	microflora					284:293	valuable microflora	275:293	valuable microflora	275:293	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	3	35	theme	LFK	540:542	arg1	attributes					500:509	main sensory attributes	487:509	main sensory attributes	487:509	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	3	35	theme	LFK	540:542	arg1	acceptability					523:535	hedonic acceptability	515:535	hedonic acceptability of LFK	515:542	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	8	36	theme	LFK	1184:1186	arg1	acidity					1173:1179	The lower acidity	1163:1179	The lower acidity	1163:1179	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	36	theme	LFK	1184:1186	arg1	assessment					1248:1257	sensory assessment	1240:1257	sensory assessment	1240:1257	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	36	theme	LFK	1184:1186	arg1	both					1213:1216	both	1213:1216	both	1213:1216	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	36	theme	LFK	1184:1186	arg1	"					1330:1330	"just about right"	1313:1330	"just about right" in JAR scale	1313:1343	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	5	37	theme	acetic	757:762	arg1	acid					764:767	acetic acid	757:767	acetic acid in LFK	757:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	1	38	theme	microflora	284:293	arg1	diversity					262:270	diversity	262:270	diversity	262:270	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	1	38	theme	microflora	284:293	arg1	composition					246:256	its unique chemical composition	226:256	its unique chemical composition	226:256	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	7	39	theme	LFK	992:994	arg1	taste					983:987	The intense sweet taste	965:987	The intense sweet taste of LFK	965:994	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	39	theme	LFK	992:994	arg1	"					1097:1097	"just about right"	1080:1097	"just about right" by 63% of elderly subjects in the just-about-right (JAR) scale	1080:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	39	theme	LFK	992:994	arg1	due					1000:1002	due	1000:1002	due	1000:1002	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	1	40	theme	them	202:205	arg1	them					202:205	them	202:205	them	202:205	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	1	40	theme	them	202:205	arg1	one					195:197	one	195:197	one	195:197	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	9	41	theme	elderly	1419:1425	arg1	subjects					1427:1434	elderly subjects	1419:1434	elderly subjects	1419:1434	These two taste attributes dominated in liking the lactose-free kefir by elderly subjects.					
36080153	8	42	dep	both	1213:1216	arg1	instrumentally					1218:1231	instrumentally	1218:1231	instrumentally	1218:1231	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	2	43	theme	kefir	414:418	arg1	attributes					387:396	the corresponding sensory attributes	361:396	the corresponding sensory attributes	361:396	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	2	43	theme	kefir	414:418	arg1	profile					349:355	the volatile compound profile	327:355	the volatile compound profile	327:355	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	5	44	theme	aroma	823:827	arg1	intensity					805:813	high intensity	800:813	high intensity of sour aroma	800:827	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	5	45	theme	acid	764:767	arg1	share					748:752	A substantial share	734:752	A substantial share of acetic acid in LFK	734:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	7	46	from	"	1097:1097	arg1	scale					1156:1160	the just-about-right (JAR) scale	1129:1160	the just-about-right (JAR) scale	1129:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	4	47	dep	ketones	607:613	arg1	times					596:600	times	596:600	times	596:600	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	8	48	theme	lower	1167:1171	arg1	acidity					1173:1179	The lower acidity	1163:1179	The lower acidity	1163:1179	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	48	theme	lower	1167:1171	arg1	assessment					1248:1257	sensory assessment	1240:1257	sensory assessment	1240:1257	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	48	theme	lower	1167:1171	arg1	both					1213:1216	both	1213:1216	both	1213:1216	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	48	theme	lower	1167:1171	arg1	"					1330:1330	"just about right"	1313:1330	"just about right" in JAR scale	1313:1343	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	2	49	theme	lactose-free	401:412	arg1	kefir					414:418	lactose-free kefir	401:418	lactose-free kefir (LFK)	401:424	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	2	49	theme	lactose-free	401:412	arg1	LFK					421:423	LFK	421:423	LFK	421:423	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	0	50	theme	Kefir	57:61	arg1	Acceptability					72:84	Its Acceptability	68:84	Its Acceptability by Elderly Consumers	68:105	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	0	50	theme	Kefir	57:61	arg1	Composition					9:19	Volatile Composition	0:19	Volatile Composition	0:19	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	0	50	theme	Kefir	57:61	arg1	Profile					33:39	Sensory Profile	25:39	Sensory Profile	25:39	Volatile Composition and Sensory Profile of Lactose-Free Kefir, and Its Acceptability by Elderly Consumers.					
36080153	5	51	theme	substantial	736:746	arg1	share					748:752	A substantial share	734:752	A substantial share of acetic acid in LFK	734:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	1	52	theme	Lactose-free	108:119	arg1	products					121:128	Lactose-free products	108:128	Lactose-free products	108:128	Lactose-free products are crucial in the diet of lactose-intolerant elderly consumers, one of them being kefir due to its unique chemical composition and diversity of valuable microflora.					
36080153	5	53	from	share	748:752	arg1	LFK					772:774	LFK	772:774	LFK	772:774	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	4	54	dep	times	596:600	arg1	more					602:605	more	602:605	more	602:605	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	8	55	theme	subjects	1301:1308	arg1	%					1288:1288	73%	1286:1288	73% of elderly subjects	1286:1308	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	55	theme	subjects	1301:1308	arg1	subjects					1301:1308	elderly subjects	1293:1308	elderly subjects	1293:1308	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	7	56	theme	just-about-right	1133:1148	arg1	scale					1156:1160	the just-about-right (JAR) scale	1129:1160	the just-about-right (JAR) scale	1129:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	57	theme	intense	969:975	arg1	taste					983:987	The intense sweet taste	965:987	The intense sweet taste of LFK	965:994	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	57	theme	intense	969:975	arg1	"					1097:1097	"just about right"	1080:1097	"just about right" by 63% of elderly subjects in the just-about-right (JAR) scale	1080:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	57	theme	intense	969:975	arg1	due					1000:1002	due	1000:1002	due	1000:1002	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	4	58	contain	contained	582:590	arg2	2,3-butanedione					652:666	2,3-butanedione	652:666	2,3-butanedione	652:666	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	4	58	contain	contained	582:590	arg1	LFK					578:580	The LFK	574:580	The LFK	574:580	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	4	58	contain	contained	582:590	arg2	3-hydroxy-2-butanone					627:646	3-hydroxy-2-butanone	627:646	3-hydroxy-2-butanone	627:646	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	4	58	contain	contained	582:590	arg2	ketones					607:613	two times more ketones	592:613	two times more ketones	592:613	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	8	59	theme	sensory	1240:1246	arg1	acidity					1173:1179	The lower acidity	1163:1179	The lower acidity	1163:1179	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	59	theme	sensory	1240:1246	arg1	assessment					1248:1257	sensory assessment	1240:1257	sensory assessment	1240:1257	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	7	60	theme	sweet	977:981	arg1	taste					983:987	The intense sweet taste	965:987	The intense sweet taste of LFK	965:994	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	60	theme	sweet	977:981	arg1	"					1097:1097	"just about right"	1080:1097	"just about right" by 63% of elderly subjects in the just-about-right (JAR) scale	1080:1160	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	60	theme	sweet	977:981	arg1	due					1000:1002	due	1000:1002	due	1000:1002	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	9	61	theme	taste	1356:1360	arg1	attributes					1362:1371	These two taste attributes	1346:1371	These two taste attributes	1346:1371	These two taste attributes dominated in liking the lactose-free kefir by elderly subjects.					
36080153	8	62	from	"	1330:1330	arg1	scale					1339:1343	JAR scale	1335:1343	JAR scale	1335:1343	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	4	63	theme	high	702:705	arg1	intensity					707:715	the high intensity	698:715	the high intensity of creamy aroma	698:731	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	8	64	theme	JAR	1335:1337	arg1	scale					1339:1343	JAR scale	1335:1343	JAR scale	1335:1343	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	5	65	theme	sour	818:821	arg1	aroma					823:827	sour aroma	818:827	sour aroma	818:827	A substantial share of acetic acid in LFK was not associated with high intensity of sour aroma, probably being masked by the creamy aroma, perceived as dominating.					
36080153	8	66	dep	assayed	1205:1211	arg1	acidity					1173:1179	The lower acidity	1163:1179	The lower acidity	1163:1179	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	66	dep	assayed	1205:1211	arg1	assessment					1248:1257	sensory assessment	1240:1257	sensory assessment	1240:1257	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	8	66	dep	assayed	1205:1211	arg1	both					1213:1216	both	1213:1216	both	1213:1216	The lower acidity of LFK than that of TK, assayed both instrumentally and by sensory assessment, was highly appreciated by 73% of elderly subjects as "just about right" in JAR scale.					
36080153	3	67	theme	main	487:490	arg1	attributes					500:509	main sensory attributes	487:509	main sensory attributes	487:509	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	7	68	theme	elderly	1109:1115	arg1	subjects					1117:1124	elderly subjects	1109:1124	elderly subjects	1109:1124	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	4	69	theme	two	592:594	arg1	times					596:600	times	596:600	times	596:600	The LFK contained two times more ketones, especially 3-hydroxy-2-butanone and 2,3-butanedione, that probably contributed to the high intensity of creamy aroma.					
36080153	2	70	theme	traditional	447:457	arg1	TK					464:465	TK	464:465	TK	464:465	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	2	70	theme	traditional	447:457	arg1	one					459:461	the traditional one	443:461	the traditional one (TK)	443:466	The study aimed at determining the volatile compound profile and the corresponding sensory attributes of lactose-free kefir (LFK) as compared with the traditional one (TK).					
36080153	7	71	from	TK	1055:1056	arg1	taste					983:987	The intense sweet taste	965:987	The intense sweet taste of LFK	965:994	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	7	71	from	TK	1055:1056	arg1	due					1000:1002	due	1000:1002	due	1000:1002	The intense sweet taste of LFK was due to higher amounts of glucose and galactose than in TK, and was perceived as "just about right" by 63% of elderly subjects in the just-about-right (JAR) scale.					
36080153	3	72	theme	sensory	492:498	arg1	attributes					500:509	main sensory attributes	487:509	main sensory attributes	487:509	The perception of main sensory attributes and hedonic acceptability of LFK by elderly were also studied.					
36080153	6	73	theme	traditional	948:958	arg1	one					960:962	the traditional one	944:962	the traditional one	944:962	LFK was sensed as sweeter and more milky than the traditional one.					
36599384	0	0	theme	drug	92:95	arg1	capacity					105:112	spatiotemporal drug release capacity	77:112	spatiotemporal drug release capacity	77:112	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	2	1	theme	fibrous	512:518	arg1	scaffold					520:527	a polycaprolactone (PCL) fibrous scaffold	487:527	a polycaprolactone (PCL) fibrous scaffold	487:527	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	0	2	theme	spatiotemporal	77:90	arg1	capacity					105:112	spatiotemporal drug release capacity	77:112	spatiotemporal drug release capacity	77:112	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	7	3	theme	universal	1211:1219	arg1	strategy					1221:1228	a universal strategy	1209:1228	a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases	1209:1383	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	3	4	theme	composite	534:542	arg1	coating					544:550	The composite coating	530:550	The composite coating	530:550	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	3	5	theme	inner	568:572	arg1	hydrogel					613:620	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	4	6	theme	HA	777:778	arg1	hydrogels					792:800	the HA and gelatin hydrogels	773:800	the HA and gelatin hydrogels	773:800	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	0	7	theme	release	97:103	arg1	capacity					105:112	spatiotemporal drug release capacity	77:112	spatiotemporal drug release capacity	77:112	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	2	8	with	coating	434:440	arg1	capacity					475:482	spatiotemporal drug release capacity	447:482	spatiotemporal drug release capacity	447:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	4	9	theme	gelatin	784:790	arg1	hydrogels					792:800	the HA and gelatin hydrogels	773:800	the HA and gelatin hydrogels	773:800	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	7	10	theme	cardiovascular	1361:1374	arg1	diseases					1376:1383	cardiovascular diseases	1361:1383	cardiovascular diseases	1361:1383	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	3	11	theme	dopamine-modified	574:590	arg1	acid					603:606	dopamine-modified hyaluronic acid	574:606	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	3	11	theme	dopamine-modified	574:590	arg1	HA					609:610	HA	609:610	HA	609:610	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	5	12	theme	PCL	987:989	arg1	meanwhile					1000:1008	the PCL scaffold meanwhile	983:1008	the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells	983:1086	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	0	13	theme	quick	118:122	arg1	endothelialization					124:141	quick endothelialization	118:141	quick endothelialization	118:141	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	1	14	from	endothelialization	309:326	arg1	grafts					340:345	vascular grafts	331:345	vascular grafts	331:345	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	0	15	with	gelatin	64:70	arg1	capacity					105:112	spatiotemporal drug release capacity	77:112	spatiotemporal drug release capacity	77:112	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	1	16	theme	vital	185:189	arg1	roles					191:195	the vital roles	181:195	the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency	181:281	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	5	17	theme	mechanical	958:967	arg1	properties					969:978	mechanical properties	958:978	mechanical properties	958:978	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	4	18	theme	drug	876:879	arg1	behavior					889:896	the vascular scaffold spatiotemporal drug release behavior	839:896	the vascular scaffold spatiotemporal drug release behavior	839:896	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	7	19	theme	vascular	1302:1309	arg1	grafts					1311:1316	vascular grafts	1302:1316	vascular grafts	1302:1316	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	5	20	theme	composite	903:911	arg1	coating					913:919	The composite coating	899:919	The composite coating	899:919	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	5	21	theme	cells	1082:1086	arg1	angiogenesis					1044:1055	angiogenesis	1044:1055	angiogenesis	1044:1055	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	5	21	theme	cells	1082:1086	arg1	proliferation					1026:1038	proliferation	1026:1038	proliferation	1026:1038	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	5	22	theme	scaffold	991:998	arg1	meanwhile					1000:1008	the PCL scaffold meanwhile	983:1008	the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells	983:1086	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	0	23	theme	Hydrogel	0:7	arg1	coating					9:15	Hydrogel coating	0:15	Hydrogel coating	0:15	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	7	24	theme	long-term	1263:1271	arg1	promotion					1289:1297	long-term anticoagulation promotion	1263:1297	long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases	1263:1383	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	3	25	theme	crosslinking	688:699	arg1	methods					701:707	different crosslinking methods	678:707	different crosslinking methods	678:707	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	4	26	theme	release	881:887	arg1	behavior					889:896	the vascular scaffold spatiotemporal drug release behavior	839:896	the vascular scaffold spatiotemporal drug release behavior	839:896	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	1	27	theme	vascular	200:207	arg1	intima					209:214	vascular intima	200:214	vascular intima	200:214	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	2	28	theme	release	467:473	arg1	capacity					475:482	spatiotemporal drug release capacity	447:482	spatiotemporal drug release capacity	447:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	1	29	theme	quick	303:307	arg1	endothelialization					309:326	quick endothelialization	303:326	quick endothelialization on vascular grafts	303:345	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	3	30	theme	hyaluronic	592:601	arg1	acid					603:606	dopamine-modified hyaluronic acid	574:606	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	3	30	theme	hyaluronic	592:601	arg1	HA					609:610	HA	609:610	HA	609:610	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	1	31	theme	intima	209:214	arg1	roles					191:195	the vital roles	181:195	the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency	181:281	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	2	32	theme	drug	462:465	arg1	capacity					475:482	spatiotemporal drug release capacity	447:482	spatiotemporal drug release capacity	447:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	5	33	theme	meanwhile	1000:1008	arg1	hydrophilicity					939:952	surface hydrophilicity	931:952	surface hydrophilicity	931:952	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	5	33	theme	meanwhile	1000:1008	arg1	properties					969:978	mechanical properties	958:978	mechanical properties	958:978	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	3	34	theme	acid	603:606	arg1	hydrogel					613:620	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	an inner dopamine-modified hyaluronic acid (HA) hydrogel	565:620	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	6	35	theme	scaffold	1140:1147	arg1	property					1115:1122	Long-term anticoagulation property	1089:1122	Long-term anticoagulation property of the modified scaffold	1089:1147	Long-term anticoagulation property of the modified scaffold was also demonstrated in vitro.					
36599384	0	36	theme	hyaluronic	44:53	arg1	acid					55:58	dopamine-modified hyaluronic acid	26:58	dopamine-modified hyaluronic acid	26:58	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	7	37	theme	grafts	1311:1316	arg1	promotion					1289:1297	long-term anticoagulation promotion	1263:1297	long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases	1263:1383	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	7	37	theme	grafts	1311:1316	arg1	endothelialization					1240:1257	quick endothelialization	1234:1257	quick endothelialization	1234:1257	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	4	38	theme	vascular	843:850	arg1	behavior					889:896	the vascular scaffold spatiotemporal drug release behavior	839:896	the vascular scaffold spatiotemporal drug release behavior	839:896	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	6	39	theme	modified	1131:1138	arg1	scaffold					1140:1147	the modified scaffold	1127:1147	the modified scaffold	1127:1147	Long-term anticoagulation property of the modified scaffold was also demonstrated in vitro.					
36599384	0	40	theme	dopamine-modified	26:42	arg1	acid					55:58	dopamine-modified hyaluronic acid	26:58	dopamine-modified hyaluronic acid	26:58	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	1	41	theme	vascular	331:338	arg1	grafts					340:345	vascular grafts	331:345	vascular grafts	331:345	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	0	42	theme	long-term	147:155	arg1	anticoagulation					157:171	long-term anticoagulation	147:171	long-term anticoagulation	147:171	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	6	43	theme	Long-term	1089:1097	arg1	property					1115:1122	Long-term anticoagulation property	1089:1122	Long-term anticoagulation property of the modified scaffold	1089:1147	Long-term anticoagulation property of the modified scaffold was also demonstrated in vitro.					
36599384	2	44	theme	hydrogel	425:432	arg1	coating					434:440	a double-layered hydrogel coating	408:440	a double-layered hydrogel coating with spatiotemporal drug release capacity	408:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	7	45	theme	quick	1234:1238	arg1	endothelialization					1240:1257	quick endothelialization	1234:1257	quick endothelialization	1234:1257	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	4	46	theme	spatiotemporal	861:874	arg1	behavior					889:896	the vascular scaffold spatiotemporal drug release behavior	839:896	the vascular scaffold spatiotemporal drug release behavior	839:896	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	2	47	theme	double-layered	410:423	arg1	coating					434:440	a double-layered hydrogel coating	408:440	a double-layered hydrogel coating with spatiotemporal drug release capacity	408:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	1	48	dep	methods	284:290	arg1	promote					295:301	promote	295:301	to promote quick endothelialization on vascular grafts	292:345	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	4	49	theme	scaffold	852:859	arg1	behavior					889:896	the vascular scaffold spatiotemporal drug release behavior	839:896	the vascular scaffold spatiotemporal drug release behavior	839:896	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	4	50	theme	chondroitin	734:744	arg1	sulfate					746:752	chondroitin sulfate	734:752	chondroitin sulfate	734:752	Especially, heparin and chondroitin sulfate were introduced to the HA and gelatin hydrogels during the processing, thus endowing the vascular scaffold spatiotemporal drug release behavior.					
36599384	7	51	theme	anticoagulation	1273:1287	arg1	promotion					1289:1297	long-term anticoagulation promotion	1263:1297	long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases	1263:1383	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	7	52	used	used	1344:1347	arg2	grafts					1311:1316	vascular grafts	1302:1316	vascular grafts	1302:1316	This investigation provides a universal strategy for quick endothelialization and long-term anticoagulation promotion of vascular grafts, which may be potentially used in treating cardiovascular diseases.					
36599384	5	53	dep	proliferation	1026:1038	arg1	the					1022:1024	the	1022:1024	the	1022:1024	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	5	53	dep	proliferation	1026:1038	arg1	behaviors					1057:1065	behaviors	1057:1065	behaviors	1057:1065	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	3	54	theme	different	678:686	arg1	methods					701:707	different crosslinking methods	678:707	different crosslinking methods	678:707	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	5	55	theme	endothelial	1070:1080	arg1	cells					1082:1086	endothelial cells	1070:1086	endothelial cells	1070:1086	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	2	56	theme	spatiotemporal	447:460	arg1	capacity					475:482	spatiotemporal drug release capacity	447:482	spatiotemporal drug release capacity	447:482	In this study, we novelly applied a double-layered hydrogel coating with spatiotemporal drug release capacity on a polycaprolactone (PCL) fibrous scaffold.					
36599384	1	57	theme	thrombus	230:237	arg1	generation					239:248	thrombus generation	230:248	thrombus generation	230:248	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	3	58	theme	outer	629:633	arg1	hydrogel					643:650	an outer gelatin hydrogel	626:650	an outer gelatin hydrogel	626:650	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	0	59	with	acid	55:58	arg1	capacity					105:112	spatiotemporal drug release capacity	77:112	spatiotemporal drug release capacity	77:112	Hydrogel coating based on dopamine-modified hyaluronic acid and gelatin with spatiotemporal drug release capacity for quick endothelialization and long-term anticoagulation.					
36599384	5	60	theme	surface	931:937	arg1	hydrophilicity					939:952	surface hydrophilicity	931:952	surface hydrophilicity	931:952	The composite coating developed surface hydrophilicity and mechanical properties of the PCL scaffold meanwhile stimulating the proliferation and angiogenesis behaviors of endothelial cells.					
36599384	6	61	theme	anticoagulation	1099:1113	arg1	property					1115:1122	Long-term anticoagulation property	1089:1122	Long-term anticoagulation property of the modified scaffold	1089:1147	Long-term anticoagulation property of the modified scaffold was also demonstrated in vitro.					
36599384	1	62	theme	much	358:361	arg1	attention					363:371	much attention	358:371	much attention	358:371	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36599384	3	63	theme	gelatin	635:641	arg1	hydrogel					643:650	an outer gelatin hydrogel	626:650	an outer gelatin hydrogel	626:650	The composite coating consisted of an inner dopamine-modified hyaluronic acid (HA) hydrogel and an outer gelatin hydrogel, which were generated via different crosslinking methods.					
36599384	1	64	theme	vascular	266:273	arg1	patency					275:281	vascular patency	266:281	vascular patency	266:281	Due to the vital roles of vascular intima in preventing thrombus generation and maintaining vascular patency, methods to promote quick endothelialization on vascular grafts have drawn much attention.					
36594427	2	0	theme	tensile	641:647	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	0	theme	tensile	641:647	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	3	1	with	elasticity	853:862	arg1	change					942:947	no obvious change	931:947	no obvious change after 10 days at ambient environment	931:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	2	2	with	glycerol	584:591	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	3	3	theme	good	869:872	arg1	properties					914:923	good self-healing, anti-freezing, non-drying properties	869:923	good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment)	869:985	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	0	4	theme	Mechanical	88:97	arg1	Properties					99:108	High Mechanical Properties	83:108	High Mechanical Properties	83:108	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	2	5	theme	ultimate	632:639	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	5	theme	ultimate	632:639	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	6	theme	potential	1262:1270	arg1	applications					1272:1283	potential applications	1262:1283	potential applications in flexible sensing and wearable devices	1262:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	3	7	theme	self-healing	874:885	arg1	properties					914:923	good self-healing, anti-freezing, non-drying properties	869:923	good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment)	869:985	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	0	8	theme	Strain	118:123	arg1	Sensors					125:131	Strain Sensors	118:131	Strain Sensors	118:131	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	5	9	theme	high	1160:1163	arg1	stability					1165:1173	high stability	1160:1173	high stability	1160:1173	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	2	10	with	starch	538:543	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	11	theme	applications	1272:1283	arg1	range					1253:1257	a wide range	1246:1257	a wide range of potential applications in flexible sensing and wearable devices	1246:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	5	12	from	devices	1318:1324	arg1	range					1253:1257	a wide range	1246:1257	a wide range of potential applications in flexible sensing and wearable devices	1246:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	0	13	with	Organo-Hydrogels	28:43	arg1	Properties					99:108	High Mechanical Properties	83:108	High Mechanical Properties	83:108	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	0	13	with	Organo-Hydrogels	28:43	arg1	Anti-Freezing					64:76	Anti-Freezing	64:76	Anti-Freezing	64:76	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	0	13	with	Organo-Hydrogels	28:43	arg1	Self-Healing					50:61	Self-Healing	50:61	Self-Healing	50:61	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	2	14	theme	failure	680:686	arg1	strain					688:693	a failure strain	678:693	a failure strain of 675-1367%	678:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	15	from	applications	1272:1283	arg1	devices					1318:1324	flexible sensing and wearable devices	1288:1324	flexible sensing and wearable devices	1288:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	2	16	theme	natural	546:552	arg1	rubber					554:559	natural rubber	546:559	natural rubber	546:559	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	17	from	range	1253:1257	arg1	devices					1318:1324	flexible sensing and wearable devices	1288:1324	flexible sensing and wearable devices	1288:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	1	18	theme	high	217:220	arg1	properties					233:242	high mechanical properties	217:242	high mechanical properties	217:242	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	18	theme	high	217:220	arg1	capabilities					289:300	non-drying capabilities	278:300	non-drying capabilities	278:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	18	theme	high	217:220	arg1	anti-freezing					259:271	anti-freezing	259:271	anti-freezing	259:271	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	18	theme	high	217:220	arg1	self-healing					245:256	self-healing	245:256	self-healing	245:256	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	19	dep	it	349:350	arg1	remains					352:358	remains	352:358	remains a great challenge	352:376	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	20	with	organo-hydrogels	165:180	arg1	properties					233:242	high mechanical properties	217:242	high mechanical properties	217:242	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	20	with	organo-hydrogels	165:180	arg1	multi-functionalities					187:207	multi-functionalities	187:207	multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities	187:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	2	21	theme	elastic	709:715	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	21	theme	elastic	709:715	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	22	theme	replacement	772:782	arg1	strategy					784:791	a solvent replacement strategy	762:791	a solvent replacement strategy	762:791	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	1	23	theme	mechanical	222:231	arg1	properties					233:242	high mechanical properties	217:242	high mechanical properties	217:242	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	23	theme	mechanical	222:231	arg1	capabilities					289:300	non-drying capabilities	278:300	non-drying capabilities	278:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	23	theme	mechanical	222:231	arg1	anti-freezing					259:271	anti-freezing	259:271	anti-freezing	259:271	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	23	theme	mechanical	222:231	arg1	self-healing					245:256	self-healing	245:256	self-healing	245:256	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	0	24	theme	Ion-Conductive	13:26	arg1	Organo-Hydrogels					28:43	Starch-Based Ion-Conductive Organo-Hydrogels	0:43	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.	0:132	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	2	25	theme	solvent	764:770	arg1	strategy					784:791	a solvent replacement strategy	762:791	a solvent replacement strategy	762:791	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	26	theme	composite	417:425	arg1	hydrogel					427:434	a starch/natural rubber composite hydrogel	393:434	a starch/natural rubber composite hydrogel	393:434	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	0	27	theme	Starch-Based	0:11	arg1	Organo-Hydrogels					28:43	Starch-Based Ion-Conductive Organo-Hydrogels	0:43	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.	0:132	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	5	28	theme	temperature	1185:1195	arg1	range					1197:1201	a wide temperature range	1178:1201	a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices	1178:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	5	29	dep	100 °C	1218:1223	arg1	to					1215:1216	to	1215:1216	to	1215:1216	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	2	30	theme	%	706:706	arg1	strain					688:693	a failure strain	678:693	a failure strain of 675-1367%	678:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	3	31	theme	ambient	966:972	arg1	environment					974:984	ambient environment	966:984	ambient environment	966:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	2	32	theme	rubber	410:415	arg1	hydrogel					427:434	a starch/natural rubber composite hydrogel	393:434	a starch/natural rubber composite hydrogel	393:434	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	33	theme	one-pot	467:473	arg1	method					475:480	a simple one-pot method	458:480	a simple one-pot method	458:480	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	34	with	rubber	554:559	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	35	with	stress	649:654	arg1	strain					688:693	a failure strain	678:693	a failure strain of 675-1367%	678:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	36	theme	simple	460:465	arg1	method					475:480	a simple one-pot method	458:480	a simple one-pot method	458:480	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	37	theme	wide	1248:1251	arg1	range					1253:1257	a wide range	1246:1257	a wide range of potential applications in flexible sensing and wearable devices	1246:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	5	38	theme	wearable	1309:1316	arg1	devices					1318:1324	flexible sensing and wearable devices	1288:1324	flexible sensing and wearable devices	1288:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	2	39	theme	ion-conductive	495:508	arg1	organo-hydrogel					510:524	then an ion-conductive organo-hydrogel	487:524	then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	487:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	40	dep	properties	620:629	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	40	dep	properties	620:629	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	41	theme	lithium	562:568	arg1	chloride					570:577	lithium chloride	562:577	lithium chloride	562:577	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	3	42	from	environment	974:984	arg1	days					958:961	10 days	955:961	10 days at ambient environment	955:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	5	43	theme	wide	1180:1183	arg1	range					1197:1201	a wide temperature range	1178:1201	a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices	1178:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	4	44	theme	human	1052:1056	arg1	movement					1058:1065	human movement	1052:1065	human movement	1052:1065	The obtained hydrogels had been successfully applied to monitor human movement with high durability (over 1000 cycles) and low hysteresis.					
36594427	3	45	theme	excellent	823:831	arg1	resistance					841:850	excellent fatigue resistance	823:850	excellent fatigue resistance	823:850	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	2	46	theme	mechanical	609:618	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	47	theme	0.087-15.2 MPa	728:741	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	47	theme	0.087-15.2 MPa	728:741	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	5	48	from	100 °C	1218:1223	arg1	range					1197:1201	a wide temperature range	1178:1201	a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices	1178:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	2	49	theme	adjustable	598:607	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	50	theme	0.15-2.33 MPa	659:671	arg1	modulus					717:723	elastic modulus	709:723	elastic modulus of 0.087-15.2 MPa	709:741	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	2	50	theme	0.15-2.33 MPa	659:671	arg1	stress					649:654	ultimate tensile stress	632:654	ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%	632:706	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	1	51	theme	bio-based	140:148	arg1	organo-hydrogels					165:180	Fully bio-based ion-conductive organo-hydrogels	134:180	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities	134:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	2	52	with	chloride	570:577	arg1	properties					620:629	adjustable mechanical properties	598:629	adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa)	598:742	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	1	53	theme	great	362:366	arg1	challenge					368:376	a great challenge	360:376	a great challenge	360:376	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	54	theme	ion-conductive	150:163	arg1	organo-hydrogels					165:180	Fully bio-based ion-conductive organo-hydrogels	134:180	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities	134:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	5	55	theme	flexible	1288:1295	arg1	devices					1318:1324	flexible sensing and wearable devices	1288:1324	flexible sensing and wearable devices	1288:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	3	56	theme	obvious	934:940	arg1	change					942:947	no obvious change	931:947	no obvious change after 10 days at ambient environment	931:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	5	57	theme	sensing	1297:1303	arg1	devices					1318:1324	flexible sensing and wearable devices	1288:1324	flexible sensing and wearable devices	1288:1324	In addition, the sensors exhibit high stability in a wide temperature range from -20 °C to 100 °C which endows it with a wide range of potential applications in flexible sensing and wearable devices.					
36594427	1	58	theme	non-drying	278:287	arg1	capabilities					289:300	non-drying capabilities	278:300	non-drying capabilities	278:300	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	1	58	theme	non-drying	278:287	arg1	properties					233:242	high mechanical properties	217:242	high mechanical properties	217:242	Fully bio-based ion-conductive organo-hydrogels with multi-functionalities such as high mechanical properties, self-healing, anti-freezing, and non-drying capabilities are still extremely rare so far, and achieving it remains a great challenge.					
36594427	0	59	theme	High	83:86	arg1	Properties					99:108	High Mechanical Properties	83:108	High Mechanical Properties	83:108	Starch-Based Ion-Conductive Organo-Hydrogels with Self-Healing, Anti-Freezing, and High Mechanical Properties towards Strain Sensors.					
36594427	3	60	dep	self-healing	874:885	arg1	non-drying					903:912	non-drying	903:912	non-drying	903:912	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	3	60	dep	self-healing	874:885	arg1	anti-freezing					888:900	anti-freezing	888:900	anti-freezing	888:900	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	3	61	with	resistance	841:850	arg1	change					942:947	no obvious change	931:947	no obvious change after 10 days at ambient environment	931:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	2	62	theme	starch/natural	395:408	arg1	hydrogel					427:434	a starch/natural rubber composite hydrogel	393:434	a starch/natural rubber composite hydrogel	393:434	In this work, a starch/natural rubber composite hydrogel was first obtained by a simple one-pot method, and then an ion-conductive organo-hydrogel composed of starch, natural rubber, lithium chloride, and glycerol with adjustable mechanical properties (ultimate tensile stress of 0.15-2.33 MPa with a failure strain of 675-1367%, elastic modulus of 0.087-15.2 MPa) was fabricated by a solvent replacement strategy.					
36594427	4	63	theme	low	1111:1113	arg1	hysteresis					1115:1124	low hysteresis	1111:1124	low hysteresis	1111:1124	The obtained hydrogels had been successfully applied to monitor human movement with high durability (over 1000 cycles) and low hysteresis.					
36594427	3	64	theme	fatigue	833:839	arg1	resistance					841:850	excellent fatigue resistance	823:850	excellent fatigue resistance	823:850	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	3	65	with	properties	914:923	arg1	change					942:947	no obvious change	931:947	no obvious change after 10 days at ambient environment	931:984	The organo-hydrogels exhibit excellent fatigue resistance, elasticity, and good self-healing, anti-freezing, non-drying properties (with no obvious change after 10 days at ambient environment).					
36594427	4	66	theme	high	1072:1075	arg1	durability					1077:1086	high durability	1072:1086	high durability (over 1000 cycles)	1072:1105	The obtained hydrogels had been successfully applied to monitor human movement with high durability (over 1000 cycles) and low hysteresis.					
36594427	4	67	theme	obtained	992:999	arg1	hydrogels					1001:1009	The obtained hydrogels	988:1009	The obtained hydrogels	988:1009	The obtained hydrogels had been successfully applied to monitor human movement with high durability (over 1000 cycles) and low hysteresis.					
35240315	2	0	from	embedded	441:448	arg1	biomaterials					453:464	biomaterials	453:464	biomaterials	453:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	10	1	theme	pre-culture	1671:1681	arg1	hMSC					1666:1669	hMSC pre-culture	1666:1681	hMSC pre-culture in spheroids	1666:1694	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	1	2	theme	hypertrophic	281:292	arg1	formation					301:309	hypertrophic tissue formation	281:309	hypertrophic tissue formation	281:309	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	12	3	theme	SIGNIFICANCE	2000:2011	arg1	STATEMENT					1987:1995	STATEMENT	1987:1995	STATEMENT OF SIGNIFICANCE	1987:2011	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	3	4	from	density	823:829	arg1	embedded					632:639	embedded	632:639	embedded	632:639	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	9	5	theme	chondrogenic-associated	1497:1519	arg1	genes					1521:1525	chondrogenic-associated genes	1497:1525	chondrogenic-associated genes	1497:1525	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	12	6	theme	In	2014:2015	arg1	studies					2023:2029	In vitro studies	2014:2029	In vitro studies investigating the chondrogenic potential of biomaterials	2014:2086	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	7	7	theme	chondrogenic	1335:1346	arg1	phenotype					1348:1356	more pronounced chondrogenic phenotype	1319:1356	more pronounced chondrogenic phenotype	1319:1356	Lower THA led to more pronounced chondrogenic phenotype compared to higher THA content.					
35240315	12	8	theme	encapsulated	2136:2147	arg1	cells					2156:2160	encapsulated single cells	2136:2160	encapsulated single cells	2136:2160	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	6	9	from	THA-Col	1174:1180	arg1	Embedding					1143:1151	Embedding	1143:1151	Embedding of hMSC spheroids in THA-Col	1143:1180	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	3	10	theme	chondrogenic	560:571	arg1	media					589:593	chondrogenic differentiation media	560:593	chondrogenic differentiation media	560:593	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	10	theme	chondrogenic	560:571	arg1	days					554:557	3 days	552:557	3 days	552:557	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	1	11	theme	Material-assisted	180:196	arg1	engineering					215:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	7	12	theme	THA	1377:1379	arg1	content					1381:1387	higher THA content	1370:1387	higher THA content	1370:1387	Lower THA led to more pronounced chondrogenic phenotype compared to higher THA content.					
35240315	12	13	theme	cells	2156:2160	arg1	contact					2125:2131	the low cell-cell contact	2107:2131	the low cell-cell contact of encapsulated single cells	2107:2160	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	17	14	dep	microtissues	2764:2775	arg1	spheroids					2783:2791	spheroids	2783:2791	spheroids	2783:2791	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	1	15	theme	tissue	208:213	arg1	engineering					215:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	14	16	from	critical	2376:2383	arg1	chondrogenesis					2398:2411	the early chondrogenesis	2388:2411	the early chondrogenesis of hMSCs	2388:2420	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	12	17	theme	low	2111:2113	arg1	contact					2125:2131	the low cell-cell contact	2107:2131	the low cell-cell contact of encapsulated single cells	2107:2160	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	3	18	theme	THA	752:754	arg1	combinations					736:747	four combinations	731:747	four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content	731:810	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	10	19	theme	chondrogenic	1727:1738	arg1	differentiation					1740:1754	chondrogenic differentiation	1727:1754	chondrogenic differentiation	1727:1754	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	7	20	theme	Lower	1302:1306	arg1	THA					1308:1310	Lower THA	1302:1310	Lower THA	1302:1310	Lower THA led to more pronounced chondrogenic phenotype compared to higher THA content.					
35240315	10	21	theme	low	1791:1793	arg1	count					1806:1810	low total cell count	1791:1810	low total cell count (5 × 106/ml)	1791:1823	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	10	21	theme	low	1791:1793	arg1	5 × 106/ml					1813:1822	5 × 106/ml	1813:1822	5 × 106/ml	1813:1822	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	16	22	theme	hypertrophic	2638:2649	arg1	expression					2656:2665	hypertrophic gene expression	2638:2665	hypertrophic gene expression	2638:2665	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	3	23	from	hydrogels	720:728	arg1	embedded					632:639	embedded	632:639	embedded	632:639	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	8	24	theme	Col	1390:1392	arg1	content					1394:1400	Col content	1390:1400	Col content	1390:1400	Col content had no significant influence on hMSC chondrogenesis.					
35240315	6	25	from	Embedding	1143:1151	arg1	THA-Col					1174:1180	THA-Col	1174:1180	THA-Col	1174:1180	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	4	26	dep	cells	925:929	arg1	ScMP					932:935	ScMP	932:935	ScMP	932:935	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	3	27	theme	acid	673:676	arg1	hydrogels					720:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels	644:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content)	644:811	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	15	28	theme	cells/ml	2457:2464	arg1	spheroids/ml					2475:2486	2 × 104 spheroids/ml	2467:2486	2 × 104 spheroids/ml	2467:2486	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	15	28	theme	cells/ml	2457:2464	arg1	density					2440:2446	a low seeding density	2426:2446	a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml)	2426:2487	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	9	29	from	production	1531:1540	arg1	genes					1521:1525	chondrogenic-associated genes	1497:1525	chondrogenic-associated genes	1497:1525	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	3	30	theme	Col	781:783	arg1	combinations					736:747	four combinations	731:747	four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content	731:810	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	31	dep	THA	752:754	arg1	content					804:810	content	804:810	content	804:810	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	32	theme	tyramine-modified	644:660	arg1	THA					679:681	THA	679:681	THA	679:681	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	32	theme	tyramine-modified	644:660	arg1	acid					673:676	tyramine-modified hyaluronic acid	644:676	tyramine-modified hyaluronic acid (THA)	644:682	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	9	33	from	upregulation	1481:1492	arg1	genes					1521:1525	chondrogenic-associated genes	1497:1525	chondrogenic-associated genes	1497:1525	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	17	34	dep	shown	2736:2740	arg1	assemble					2755:2762	assemble	2755:2762	to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs	2752:2847	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	17	34	dep	shown	2736:2740	arg1	study					2856:2860	study	2856:2860	to study the effect of biomaterial composition on cell alignment and migration	2853:2930	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	2	35	theme	cell	516:519	arg1	differentiation					521:535	cell differentiation	516:535	cell differentiation	516:535	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	2	36	from	biomaterials	453:464	arg1	embedded					441:448	embedded	441:448	embedded	441:448	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	0	37	theme	cartilage	156:164	arg1	microtissues					166:177	cartilage microtissues	156:177	cartilage microtissues	156:177	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	12	38	theme	biomaterials	2075:2086	arg1	potential					2062:2070	the chondrogenic potential	2045:2070	the chondrogenic potential of biomaterials	2045:2086	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	6	39	theme	GAGs	1295:1298	arg1	production					1281:1290	the production	1277:1290	the production of GAGs	1277:1298	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	39	theme	GAGs	1295:1298	arg1	ACAN					1255:1258	ACAN	1255:1258	ACAN	1255:1258	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	39	theme	GAGs	1295:1298	arg1	COL2A1					1265:1270	COL2A1	1265:1270	COL2A1	1265:1270	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	39	theme	GAGs	1295:1298	arg1	upregulation					1229:1240	upregulation	1229:1240	upregulation of aggrecan (ACAN)	1229:1259	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	0	40	theme	low	92:94	arg1	count					107:111	a low total cell count	90:111	a low total cell count	90:111	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	5	41	theme	hMSC	1014:1017	arg1	differentiation					1019:1033	hMSC differentiation	1014:1033	hMSC differentiation	1014:1033	hMSC differentiation was analyzed using glycosaminoglycan (GAG) quantification, gene expression analysis and (immuno-)histology.					
35240315	15	42	theme	cartilaginous	2529:2541	arg1	deposition					2550:2559	cartilaginous matrix deposition	2529:2559	cartilaginous matrix deposition	2529:2559	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	17	43	theme	composition	2888:2898	arg1	effect					2866:2871	the effect	2862:2871	the effect of biomaterial composition on cell alignment and migration	2862:2930	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	2	44	from	effect	479:484	arg1	differentiation					521:535	cell differentiation	516:535	cell differentiation	516:535	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	14	45	theme	cell-cell	2331:2339	arg1	contact					2341:2347	the high cell-cell contact	2322:2347	the high cell-cell contact	2322:2347	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	0	46	theme	cell	102:105	arg1	count					107:111	a low total cell count	90:111	a low total cell count	90:111	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	4	47	theme	hMSC	941:944	arg1	spheroids					946:954	hMSC spheroids	941:954	hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP)	941:993	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	47	theme	hMSC	941:944	arg1	cells					967:971	2.5 × 105 cells, 103 spheroids, SpMP	957:992	cells	967:971	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	48	attach	derived	888:894	arg1	spheroids					946:954	hMSC spheroids	941:954	hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP)	941:993	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	48	attach	derived	888:894	arg1	cells					967:971	2.5 × 105 cells, 103 spheroids, SpMP	957:992	cells	967:971	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	48	attach	derived	888:894	arg2	Macropellets					875:886	Macropellets	875:886	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP)	875:993	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	48	attach	derived	888:894	arg1	hMSCs					908:912	single hMSCs	901:912	single hMSCs (2.5 × 105 cells, ScMP)	901:936	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	48	attach	derived	888:894	arg1	cells					925:929	2.5 × 105 cells, ScMP	915:935	cells	925:929	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	2	49	theme	cell	419:422	arg1	spheroids					431:439	human mesenchymal stromal cell (hMSC) spheroids	393:439	human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials	393:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	5	50	theme	expression	1099:1108	arg1	analysis					1110:1117	gene expression analysis	1094:1117	gene expression analysis	1094:1117	hMSC differentiation was analyzed using glycosaminoglycan (GAG) quantification, gene expression analysis and (immuno-)histology.					
35240315	10	51	from	count	1806:1810	arg1	encapsulation					1774:1786	biomaterial encapsulation	1762:1786	biomaterial encapsulation at low total cell count (5 × 106/ml)	1762:1823	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	12	52	dep	In	2014:2015	arg1	vitro					2017:2021	vitro	2017:2021	vitro	2017:2021	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	0	53	theme	human	15:19	arg1	cells					41:45	human mesenchymal stromal cells	15:45	human mesenchymal stromal cells in spheroids	15:58	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	1	54	theme	cell	320:323	arg1	counts					325:330	high cell counts	315:330	high cell counts required	315:339	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	14	55	from	chondrogenesis	2398:2411	arg1	critical					2376:2383	critical	2376:2383	critical	2376:2383	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	2	56	theme	composition	501:511	arg1	effect					479:484	the effect	475:484	the effect of biomaterial composition on cell differentiation	475:535	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	3	57	from	embedded	632:639	arg1	hydrogels					720:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels	644:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content)	644:811	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	2	58	theme	spheroids	431:439	arg1	potential					380:388	the potential	376:388	the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation	376:535	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	0	59	theme	stromal	33:39	arg1	cells					41:45	human mesenchymal stromal cells	15:45	human mesenchymal stromal cells in spheroids	15:58	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	13	60	theme	pre-cultured	2193:2204	arg1	spheroids					2211:2219	pre-cultured hMSC spheroids	2193:2219	pre-cultured hMSC spheroids	2193:2219	Here, we introduce the use of pre-cultured hMSC spheroids to study chondrogenesis upon encapsulation in a biomaterial.					
35240315	17	61	theme	cartilage	2828:2836	arg1	constructs					2838:2847	large cartilage constructs	2822:2847	large cartilage constructs	2822:2847	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	9	62	theme	GAGs	1545:1548	arg1	upregulation					1481:1492	an upregulation	1478:1492	an upregulation in chondrogenic-associated genes	1478:1525	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	9	62	theme	GAGs	1545:1548	arg1	production					1531:1540	production	1531:1540	production of GAGs	1531:1548	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	13	63	theme	spheroids	2211:2219	arg1	use					2186:2188	the use	2182:2188	the use of pre-cultured hMSC spheroids to study chondrogenesis upon encapsulation in a biomaterial	2182:2279	Here, we introduce the use of pre-cultured hMSC spheroids to study chondrogenesis upon encapsulation in a biomaterial.					
35240315	15	64	theme	seeding	2432:2438	arg1	spheroids/ml					2475:2486	2 × 104 spheroids/ml	2467:2486	2 × 104 spheroids/ml	2467:2486	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	15	64	theme	seeding	2432:2438	arg1	density					2440:2446	a low seeding density	2426:2446	a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml)	2426:2487	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	9	65	theme	less	1555:1558	arg1	upregulation					1560:1571	less upregulation	1555:1571	less upregulation of hypertrophic-associated genes in SpMP culture	1555:1620	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	8	66	contain	had	1402:1404	arg1	content					1394:1400	Col content	1390:1400	Col content	1390:1400	Col content had no significant influence on hMSC chondrogenesis.					
35240315	8	66	contain	had	1402:1404	arg2	influence					1421:1429	no significant influence	1406:1429	no significant influence	1406:1429	Col content had no significant influence on hMSC chondrogenesis.					
35240315	10	67	theme	cell	1801:1804	arg1	count					1806:1810	low total cell count	1791:1810	low total cell count (5 × 106/ml)	1791:1823	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	10	67	theme	cell	1801:1804	arg1	5 × 106/ml					1813:1822	5 × 106/ml	1813:1822	5 × 106/ml	1813:1822	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	10	68	theme	promising	1699:1707	arg1	approach					1709:1716	promising approach	1699:1716	promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production	1699:1875	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	3	69	theme	type	697:700	arg1	hydrogels					720:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels	644:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content)	644:811	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	2	70	theme	mesenchymal	399:409	arg1	hMSC					425:428	hMSC	425:428	hMSC	425:428	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	2	70	theme	mesenchymal	399:409	arg1	cell					419:422	mesenchymal stromal cell	399:422	human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials	393:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	9	71	theme	genes	1600:1604	arg1	upregulation					1560:1571	less upregulation	1555:1571	less upregulation of hypertrophic-associated genes in SpMP culture	1555:1620	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	3	72	theme	Pre-cultured	538:549	arg1	spheroids					596:604	Pre-cultured (3 days, chondrogenic differentiation media) spheroids	538:604	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid)	538:625	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	72	theme	Pre-cultured	538:549	arg1	cells/spheroid					611:624	250 cells/spheroid	607:624	250 cells/spheroid	607:624	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	5	73	theme	immuno-	1124:1130	arg1	histology					1132:1140	(immuno-)histology	1123:1140	(immuno-)histology	1123:1140	hMSC differentiation was analyzed using glycosaminoglycan (GAG) quantification, gene expression analysis and (immuno-)histology.					
35240315	8	74	theme	significant	1409:1419	arg1	influence					1421:1429	no significant influence	1406:1429	no significant influence	1406:1429	Col content had no significant influence on hMSC chondrogenesis.					
35240315	9	75	theme	SpMP	1609:1612	arg1	culture					1614:1620	SpMP culture	1609:1620	SpMP culture	1609:1620	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	17	76	theme	large	2822:2826	arg1	constructs					2838:2847	large cartilage constructs	2822:2847	large cartilage constructs	2822:2847	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	14	77	theme	early	2392:2396	arg1	chondrogenesis					2398:2411	the early chondrogenesis	2388:2411	the early chondrogenesis of hMSCs	2388:2420	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	3	78	theme	differentiation	573:587	arg1	media					589:593	chondrogenic differentiation media	560:593	chondrogenic differentiation media	560:593	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	78	theme	differentiation	573:587	arg1	days					554:557	3 days	552:557	3 days	552:557	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	1	79	theme	tissue	294:299	arg1	formation					301:309	hypertrophic tissue formation	281:309	hypertrophic tissue formation	281:309	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	10	80	from	hMSC	1666:1669	arg1	spheroids					1686:1694	spheroids	1686:1694	spheroids	1686:1694	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	6	81	theme	chondrogenic	1190:1201	arg1	differentiation					1203:1217	chondrogenic differentiation	1190:1217	chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs	1190:1298	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	7	82	theme	higher	1370:1375	arg1	content					1381:1387	higher THA content	1370:1387	higher THA content	1370:1387	Lower THA led to more pronounced chondrogenic phenotype compared to higher THA content.					
35240315	9	83	theme	ScMP	1634:1637	arg1	group					1639:1643	ScMP group	1634:1643	ScMP group	1634:1643	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	4	84	dep	cells	967:971	arg1	spheroids					978:986	103 spheroids	974:986	103 spheroids	974:986	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	10	85	theme	biomaterial	1762:1772	arg1	encapsulation					1774:1786	biomaterial encapsulation	1762:1786	biomaterial encapsulation at low total cell count (5 × 106/ml)	1762:1823	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	1	86	theme	cartilage	198:206	arg1	engineering					215:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	16	87	theme	beneficial	2617:2626	arg1	effect					2628:2633	a beneficial effect	2615:2633	a beneficial effect	2615:2633	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	7	88	theme	pronounced	1324:1333	arg1	phenotype					1348:1356	more pronounced chondrogenic phenotype	1319:1356	more pronounced chondrogenic phenotype	1319:1356	Lower THA led to more pronounced chondrogenic phenotype compared to higher THA content.					
35240315	12	89	theme	single	2149:2154	arg1	cells					2156:2160	encapsulated single cells	2136:2160	encapsulated single cells	2136:2160	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	16	90	contain	have	2610:2613	arg1	pre-culture					2592:2602	pre-culture	2592:2602	pre-culture	2592:2602	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	16	90	contain	have	2610:2613	arg2	effect					2628:2633	a beneficial effect	2615:2633	a beneficial effect	2615:2633	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	10	91	theme	total	1795:1799	arg1	count					1806:1810	low total cell count	1791:1810	low total cell count (5 × 106/ml)	1791:1823	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	10	91	theme	total	1795:1799	arg1	5 × 106/ml					1813:1822	5 × 106/ml	1813:1822	5 × 106/ml	1813:1822	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	1	92	theme	limited	231:237	arg1	application					239:249	limited application	231:249	limited application in cartilage treatment	231:272	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	16	93	theme	gene	2651:2654	arg1	expression					2656:2665	hypertrophic gene expression	2638:2665	hypertrophic gene expression	2638:2665	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	6	94	theme	hMSC	1156:1159	arg1	spheroids					1161:1169	hMSC spheroids	1156:1169	hMSC spheroids in THA-Col	1156:1180	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	12	95	theme	cell-cell	2115:2123	arg1	contact					2125:2131	the low cell-cell contact	2107:2131	the low cell-cell contact of encapsulated single cells	2107:2160	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	14	96	theme	contact	2341:2347	arg1	advantage					2309:2317	advantage	2309:2317	advantage of the high cell-cell contact	2309:2347	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	1	97	from	application	239:249	arg1	treatment					264:272	cartilage treatment	254:272	cartilage treatment	254:272	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	0	98	from	count	107:111	arg1	chondrogenesis					72:85	chondrogenesis	72:85	chondrogenesis at a low total cell count	72:111	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	11	99	from	microtissues	1919:1930	arg1	biomaterials					1935:1946	biomaterials	1935:1946	biomaterials	1935:1946	This approach can be applied to assemble microtissues in biomaterials to generate large cartilage construct.					
35240315	6	100	theme	aggrecan	1245:1252	arg1	production					1281:1290	the production	1277:1290	the production of GAGs	1277:1298	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	100	theme	aggrecan	1245:1252	arg1	ACAN					1255:1258	ACAN	1255:1258	ACAN	1255:1258	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	100	theme	aggrecan	1245:1252	arg1	COL2A1					1265:1270	COL2A1	1265:1270	COL2A1	1265:1270	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	6	100	theme	aggrecan	1245:1252	arg1	upregulation					1229:1240	upregulation	1229:1240	upregulation of aggrecan (ACAN)	1229:1259	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	3	101	theme	hyaluronic	662:671	arg1	THA					679:681	THA	679:681	THA	679:681	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	101	theme	hyaluronic	662:671	arg1	acid					673:676	tyramine-modified hyaluronic acid	644:676	tyramine-modified hyaluronic acid (THA)	644:682	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	102	theme	cell	818:821	arg1	density					823:829	a cell density	816:829	a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml)	816:872	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	6	103	from	spheroids	1161:1169	arg1	THA-Col					1174:1180	THA-Col	1174:1180	THA-Col	1174:1180	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	11	104	theme	cartilage	1966:1974	arg1	construct					1976:1984	large cartilage construct	1960:1984	large cartilage construct	1960:1984	This approach can be applied to assemble microtissues in biomaterials to generate large cartilage construct.					
35240315	12	105	theme	chondrogenic	2049:2060	arg1	potential					2062:2070	the chondrogenic potential	2045:2070	the chondrogenic potential of biomaterials	2045:2086	STATEMENT OF SIGNIFICANCE: In vitro studies investigating the chondrogenic potential of biomaterials are limited due to the low cell-cell contact of encapsulated single cells.					
35240315	17	106	theme	biomaterial	2876:2886	arg1	composition					2888:2898	biomaterial composition	2876:2898	biomaterial composition	2876:2898	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	5	107	theme	glycosaminoglycan	1054:1070	arg1	quantification					1078:1091	glycosaminoglycan (GAG) quantification	1054:1091	glycosaminoglycan (GAG) quantification	1054:1091	hMSC differentiation was analyzed using glycosaminoglycan (GAG) quantification, gene expression analysis and (immuno-)histology.					
35240315	9	108	theme	Pellet	1455:1460	arg1	cultures					1462:1469	Pellet cultures	1455:1469	Pellet cultures	1455:1469	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	3	109	theme	cells/ml	842:849	arg1	density					823:829	a cell density	816:829	a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml)	816:872	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	8	110	theme	hMSC	1434:1437	arg1	chondrogenesis					1439:1452	hMSC chondrogenesis	1434:1452	hMSC chondrogenesis	1434:1452	Col content had no significant influence on hMSC chondrogenesis.					
35240315	1	111	contain	has	227:229	arg2	application					239:249	limited application	231:249	limited application in cartilage treatment	231:272	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	1	111	contain	has	227:229	arg1	engineering					215:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering	180:225	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	9	112	from	upregulation	1560:1571	arg1	culture					1614:1620	SpMP culture	1609:1620	SpMP culture	1609:1620	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	0	113	theme	total	96:100	arg1	count					107:111	a low total cell count	90:111	a low total cell count	90:111	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	15	114	theme	low	2428:2430	arg1	spheroids/ml					2475:2486	2 × 104 spheroids/ml	2467:2486	2 × 104 spheroids/ml	2467:2486	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	15	114	theme	low	2428:2430	arg1	density					2440:2446	a low seeding density	2426:2446	a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml)	2426:2487	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	4	115	theme	single	901:906	arg1	hMSCs					908:912	single hMSCs	901:912	single hMSCs (2.5 × 105 cells, ScMP)	901:936	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	4	115	theme	single	901:906	arg1	cells					925:929	2.5 × 105 cells, ScMP	915:935	cells	925:929	Macropellets derived from single hMSCs (2.5 × 105 cells, ScMP) or hMSC spheroids (2.5 × 105 cells, 103 spheroids, SpMP) served as control.					
35240315	14	116	theme	spheroids	2293:2301	arg1	use					2286:2288	The use	2282:2288	The use of spheroids	2282:2301	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	15	117	theme	matrix	2543:2548	arg1	deposition					2550:2559	cartilaginous matrix deposition	2529:2559	cartilaginous matrix deposition	2529:2559	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	17	118	dep	cell	2903:2906	arg1	alignment					2908:2916	alignment	2908:2916	alignment	2908:2916	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	0	119	from	cells	41:45	arg1	spheroids					50:58	spheroids	50:58	spheroids	50:58	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	17	120	dep	spheroids	2783:2791	arg1	here					2778:2781	here	2778:2781	here	2778:2781	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	14	121	theme	high	2326:2329	arg1	contact					2341:2347	the high cell-cell contact	2322:2347	the high cell-cell contact	2322:2347	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	3	122	dep	Pre-cultured	538:549	arg1	media					589:593	chondrogenic differentiation media	560:593	chondrogenic differentiation media	560:593	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	122	dep	Pre-cultured	538:549	arg1	days					554:557	3 days	552:557	3 days	552:557	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	10	123	theme	matrix	1859:1864	arg1	production					1866:1875	chondrogenic matrix production	1846:1875	chondrogenic matrix production	1846:1875	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	2	124	theme	stromal	411:417	arg1	hMSC					425:428	hMSC	425:428	hMSC	425:428	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	2	124	theme	stromal	411:417	arg1	cell					419:422	mesenchymal stromal cell	399:422	human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials	393:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	0	125	theme	mesenchymal	21:31	arg1	cells					41:45	human mesenchymal stromal cells	15:45	human mesenchymal stromal cells in spheroids	15:58	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	1	126	theme	high	315:318	arg1	counts					325:330	high cell counts	315:330	high cell counts required	315:339	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	15	127	theme	hMSC	2505:2508	arg1	chondrogenesis					2510:2523	hMSC chondrogenesis	2505:2523	hMSC chondrogenesis	2505:2523	At a low seeding density of 5·106 cells/ml (2 × 104 spheroids/ml) we demonstrated hMSC chondrogenesis and cartilaginous matrix deposition.					
35240315	6	128	theme	spheroids	1161:1169	arg1	Embedding					1143:1151	Embedding	1143:1151	Embedding of hMSC spheroids in THA-Col	1143:1180	Embedding of hMSC spheroids in THA-Col induced chondrogenic differentiation marked by upregulation of aggrecan (ACAN) and COL2A1, and the production of GAGs .					
35240315	10	129	theme	chondrogenic	1846:1857	arg1	production					1866:1875	chondrogenic matrix production	1846:1875	chondrogenic matrix production	1846:1875	This study presents hMSC pre-culture in spheroids as promising approach to study chondrogenic differentiation after biomaterial encapsulation at low total cell count (5 × 106/ml) without compromising chondrogenic matrix production.					
35240315	2	130	theme	embedded	441:448	arg1	spheroids					431:439	human mesenchymal stromal cell (hMSC) spheroids	393:439	human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials	393:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	0	131	theme	cells	41:45	arg1	Pre-culture					0:10	Pre-culture	0:10	Pre-culture	0:10	Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.					
35240315	3	132	dep	hydrogels	720:728	arg1	combinations					736:747	four combinations	731:747	four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content	731:810	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	2	133	theme	biomaterial	489:499	arg1	composition					501:511	biomaterial composition	489:511	biomaterial composition	489:511	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	13	134	theme	hMSC	2206:2209	arg1	spheroids					2211:2219	pre-cultured hMSC spheroids	2193:2219	pre-cultured hMSC spheroids	2193:2219	Here, we introduce the use of pre-cultured hMSC spheroids to study chondrogenesis upon encapsulation in a biomaterial.					
35240315	16	135	theme	chondrogenic	2688:2699	arg1	differentiation					2701:2715	chondrogenic differentiation	2688:2715	chondrogenic differentiation	2688:2715	Our results indicate that the pre-culture might have a beneficial effect on hypertrophic gene expression without compromising chondrogenic differentiation.					
35240315	5	136	theme	gene	1094:1097	arg1	analysis					1110:1117	gene expression analysis	1094:1117	gene expression analysis	1094:1117	hMSC differentiation was analyzed using glycosaminoglycan (GAG) quantification, gene expression analysis and (immuno-)histology.					
35240315	17	137	from	effect	2866:2871	arg1	cell					2903:2906	cell alignment and migration	2903:2930	cell	2903:2906	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	17	137	from	effect	2866:2871	arg1	migration					2922:2930	migration	2922:2930	migration	2922:2930	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
35240315	11	138	theme	large	1960:1964	arg1	construct					1976:1984	large cartilage construct	1960:1984	large cartilage construct	1960:1984	This approach can be applied to assemble microtissues in biomaterials to generate large cartilage construct.					
35240315	3	139	theme	collagen	688:695	arg1	type					697:700	collagen type I	688:702	collagen type I (Col)	688:708	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	3	139	theme	collagen	688:695	arg1	Col					705:707	Col	705:707	Col	705:707	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	1	140	theme	cartilage	254:262	arg1	treatment					264:272	cartilage treatment	254:272	cartilage treatment	254:272	Material-assisted cartilage tissue engineering has limited application in cartilage treatment due to hypertrophic tissue formation and high cell counts required.					
35240315	9	141	theme	hypertrophic-associated	1576:1598	arg1	genes					1600:1604	hypertrophic-associated genes	1576:1604	hypertrophic-associated genes	1576:1604	Pellet cultures showed an upregulation in chondrogenic-associated genes and production of GAGs with less upregulation of hypertrophic-associated genes in SpMP culture compared to ScMP group.					
35240315	3	142	theme	composite	710:718	arg1	hydrogels					720:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels	644:728	tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content)	644:811	Pre-cultured (3 days, chondrogenic differentiation media) spheroids (250 cells/spheroid) were embedded in tyramine-modified hyaluronic acid (THA) and collagen type I (Col) composite hydrogels (four combinations of THA (12.5 vs 16.7 mg/ml) and Col (2.5 vs 1.7 mg/ml) content) at a cell density of 5 × 106 cells/ml (2 × 104 spheroids/ml).					
35240315	14	143	theme	hMSCs	2416:2420	arg1	chondrogenesis					2398:2411	the early chondrogenesis	2388:2411	the early chondrogenesis of hMSCs	2388:2420	The use of spheroids takes advantage of the high cell-cell contact within each spheroid being critical in the early chondrogenesis of hMSCs.					
35240315	2	144	theme	human	393:397	arg1	spheroids					431:439	human mesenchymal stromal cell (hMSC) spheroids	393:439	human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials	393:464	This study aimed at investigating the potential of human mesenchymal stromal cell (hMSC) spheroids embedded in biomaterials to study the effect of biomaterial composition on cell differentiation.					
35240315	17	145	from	microtissues	2764:2775	arg1	biomaterials					2797:2808	biomaterials	2797:2808	biomaterials	2797:2808	This approach has shown potential to assemble microtissues (here spheroids) in biomaterials to generate large cartilage constructs and to study the effect of biomaterial composition on cell alignment and migration.					
36737943	11	0	theme	dysphagia	2266:2274	arg1	food					2276:2279	the novel soft gel-type dysphagia food	2242:2279	the novel soft gel-type dysphagia food	2242:2279	These findings provide insights for the development of the novel soft gel-type dysphagia food.					
36737943	8	1	theme	water-holding	1661:1673	arg1	capacity					1675:1682	the highest water-holding capacity	1649:1682	the highest water-holding capacity	1649:1682	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	1	2	theme	structural	221:230	arg1	properties					247:256	the structural and functional properties	217:256	the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	217:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	11	3	theme	soft	2252:2255	arg1	food					2276:2279	the novel soft gel-type dysphagia food	2242:2279	the novel soft gel-type dysphagia food	2242:2279	These findings provide insights for the development of the novel soft gel-type dysphagia food.					
36737943	5	4	theme	lower	1201:1205	arg1	moduli					1220:1225	lower viscoelastic moduli	1201:1225	lower viscoelastic moduli	1201:1225	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	2	5	theme	resonance	582:590	arg1	analyses					630:637	rheological and textural analyses	605:637	rheological and textural analyses	605:637	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	5	theme	resonance	582:590	arg1	measurement					592:602	low-field nuclear magnetic resonance measurement	555:602	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	5	theme	resonance	582:590	arg1	fourier					640:646	fourier	640:646	fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy	640:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	6	theme	scanning	729:736	arg1	microscopy					738:747	confocal laser scanning microscopy	714:747	confocal laser scanning microscopy	714:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	7	theme	nuclear	565:571	arg1	resonance					582:590	low-field nuclear magnetic resonance	555:590	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	8	theme	confocal	714:721	arg1	microscopy					738:747	confocal laser scanning microscopy	714:747	confocal laser scanning microscopy	714:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	10	9	theme	International	1922:1934	arg1	IDDSI					1979:1983	IDDSI	1979:1983	IDDSI	1979:1983	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	9	theme	International	1922:1934	arg1	initiative					1967:1976	International dysphagia diet standardization initiative	1922:1976	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	9	10	theme	lamellar	1883:1890	arg1	structure					1892:1900	the obvious lamellar structure	1871:1900	the obvious lamellar structure within the network	1871:1919	The gels adding CDP presented lower hardness and gumminess due to the obvious lamellar structure within the network.					
36737943	1	11	theme	calcium	179:185	arg1	CDP					209:211	CDP	209:211	CDP	209:211	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	11	theme	calcium	179:185	arg1	phosphate					198:206	calcium dihydrogen phosphate	179:206	calcium dihydrogen phosphate (CDP)	179:212	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	10	12	theme	initiative	1967:1976	arg1	tests					1986:1990	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	8	13	contain	had	1645:1647	arg2	capacity					1675:1682	the highest water-holding capacity	1649:1682	the highest water-holding capacity	1649:1682	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	8	13	contain	had	1645:1647	arg1	CL					1642:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	1	14	theme	phosphate	198:206	arg1	Effects					119:125	Effects	119:125	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	119:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	7	15	theme	decreased	1587:1595	arg1	thickness					1602:1610	the decreased wall thickness	1583:1610	the decreased wall thickness	1583:1610	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	10	16	theme	diet	1946:1949	arg1	IDDSI					1979:1983	IDDSI	1979:1983	IDDSI	1979:1983	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	16	theme	diet	1946:1949	arg1	initiative					1967:1976	International dysphagia diet standardization initiative	1922:1976	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	6	17	theme	calcium	1291:1297	arg1	salts					1299:1303	different calcium salts	1281:1303	different calcium salts	1281:1303	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	8	18	theme	immobilized	1727:1737	arg1	water					1750:1754	more immobilized and mobile water	1722:1754	more immobilized and mobile water	1722:1754	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	1	19	theme	calcium	130:136	arg1	gluconate					138:146	calcium gluconate	130:146	calcium gluconate (CG)	130:151	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	19	theme	calcium	130:136	arg1	CG					149:150	CG	149:150	CG	149:150	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	6	20	contain	had	1305:1307	arg2	impacts					1317:1323	various impacts	1309:1323	various impacts	1309:1323	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	6	20	contain	had	1305:1307	arg1	salts					1299:1303	different calcium salts	1281:1303	different calcium salts	1281:1303	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	8	21	theme	mobile	1743:1748	arg1	water					1750:1754	more immobilized and mobile water	1722:1754	more immobilized and mobile water	1722:1754	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	2	22	dep	fourier	640:646	arg1	transform					648:656	transform	648:656	transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy	648:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	7	23	theme	pore	1567:1570	arg1	number					1572:1577	the increased pore number	1553:1577	the increased pore number	1553:1577	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	2	24	theme	composite	468:476	arg1	gels					478:481	MBS-FP composite gels	461:481	MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	461:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	4	25	theme	weak	1125:1128	arg1	network					1134:1140	a weak gel network	1123:1140	a weak gel network	1123:1140	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	3	26	theme	calcium	770:776	arg1	salts					778:782	calcium salts	770:782	calcium salts	770:782	Results showed that calcium salts imparted various soft gel properties to the composite gels by influencing the interactions between MBS and FP.					
36737943	6	27	theme	diverse	1360:1366	arg1	ability					1368:1374	their diverse ability	1354:1374	their diverse ability forming hydrogen bonds	1354:1397	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	1	28	theme	-flaxseed	283:291	arg1	gels					316:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	7	29	contain	containing	1435:1444	arg2	CG					1446:1447	CG	1446:1447	CG	1446:1447	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	7	29	contain	containing	1435:1444	arg1	gels					1430:1433	the gels	1426:1433	the gels containing CG	1426:1447	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	5	30	theme	calcium	1157:1163	arg1	gels					1189:1192	calcium salts-induced composite gels	1157:1192	calcium salts-induced composite gels	1157:1192	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	2	31	theme	scanning	681:688	arg1	microscopy					699:708	scanning electron microscopy	681:708	scanning electron microscopy	681:708	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	8	32	theme	compact	1763:1769	arg1	network					1775:1781	the compact gel network	1759:1781	the compact gel network with larger cavities	1759:1802	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	1	33	theme	calcium	154:160	arg1	CL					171:172	CL	171:172	CL	171:172	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	33	theme	calcium	154:160	arg1	lactate					162:168	calcium lactate	154:168	calcium lactate (CL)	154:173	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	10	34	dep	level	2159:2163	arg1	moist					2179:2183	moist	2179:2183	moist	2179:2183	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	34	dep	level	2159:2163	arg1	minced					2168:2173	minced	2168:2173	minced	2168:2173	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	2	35	theme	calcium	500:506	arg1	salts					508:512	different calcium salts	490:512	different calcium salts (10, 30, and 50 mmol/L)	490:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	36	theme	rheological	605:615	arg1	analyses					630:637	rheological and textural analyses	605:637	rheological and textural analyses	605:637	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	36	theme	rheological	605:615	arg1	measurement					592:602	low-field nuclear magnetic resonance measurement	555:602	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	5	37	theme	control	1253:1259	arg1	gel					1261:1263	the control gel	1249:1263	the control gel	1249:1263	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	3	38	theme	soft	801:804	arg1	properties					810:819	various soft gel properties	793:819	various soft gel properties	793:819	Results showed that calcium salts imparted various soft gel properties to the composite gels by influencing the interactions between MBS and FP.					
36737943	0	39	theme	dysphagia	103:111	arg1	food					113:116	dysphagia food	103:116	dysphagia food	103:116	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	7	40	theme	irregular	1521:1529	arg1	network					1540:1546	an irregular cellular network	1518:1546	an irregular cellular network	1518:1546	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	4	41	theme	amylose	942:948	arg1	chains					950:955	amylose chains	942:955	amylose chains	942:955	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	1	42	theme	functional	236:245	arg1	properties					247:256	the structural and functional properties	217:256	the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	217:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	43	theme	gels	316:319	arg1	properties					247:256	the structural and functional properties	217:256	the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	217:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	8	44	theme	larger	1788:1793	arg1	cavities					1795:1802	larger cavities	1788:1802	larger cavities	1788:1802	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	2	45	theme	water-immobilizing	400:417	arg1	properties					447:456	The water-immobilizing, rheological and structural properties	396:456	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	396:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	1	46	theme	bean	266:269	arg1	MBS					279:281	MBS	279:281	MBS	279:281	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	46	theme	bean	266:269	arg1	starch					271:276	mung bean starch	261:276	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	0	47	theme	Textural	0:7	arg1	characterization					9:24	Textural characterization	0:24	Textural characterization of calcium salts-induced mung bean	0:59	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	2	48	theme	textural	621:628	arg1	analyses					630:637	rheological and textural analyses	605:637	rheological and textural analyses	605:637	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	48	theme	textural	621:628	arg1	measurement					592:602	low-field nuclear magnetic resonance measurement	555:602	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	1	49	theme	mung	261:264	arg1	bean					266:269	mung bean	261:269	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	2	50	theme	structural	436:445	arg1	properties					447:456	The water-immobilizing, rheological and structural properties	396:456	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	396:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	4	51	theme	large	1102:1106	arg1	aggregates					1108:1117	large aggregates	1102:1117	large aggregates	1102:1117	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	0	52	theme	salts-induced	37:49	arg1	bean					56:59	calcium salts-induced mung bean	29:59	calcium salts-induced mung bean	29:59	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	1	53	theme	starch	271:276	arg1	gels					316:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	4	54	theme	molecules	991:999	arg1	aggregation					973:983	the aggregation	969:983	the aggregation of FP molecules	969:999	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	4	55	theme	chains	950:955	arg1	conformation					926:937	the conformation	922:937	the conformation of amylose chains	922:955	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	0	56	theme	bean	56:59	arg1	characterization					9:24	Textural characterization	0:24	Textural characterization of calcium salts-induced mung bean	0:59	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	8	57	theme	gel	1617:1619	arg1	CL					1642:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	1	58	from	Effects	119:125	arg1	properties					247:256	the structural and functional properties	217:256	the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	217:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	5	59	theme	viscoelastic	1207:1218	arg1	moduli					1220:1225	lower viscoelastic moduli	1201:1225	lower viscoelastic moduli	1201:1225	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	7	60	theme	higher	1463:1468	arg1	moduli					1483:1488	the higher viscoelastic moduli	1459:1488	the higher viscoelastic moduli	1459:1488	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	8	61	with	network	1775:1781	arg1	cavities					1795:1802	larger cavities	1788:1802	larger cavities	1788:1802	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	8	62	theme	50 mmol/L	1632:1640	arg1	CL					1642:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	2	63	theme	rheological	420:430	arg1	properties					447:456	The water-immobilizing, rheological and structural properties	396:456	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	396:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	11	64	theme	gel-type	2257:2264	arg1	food					2276:2279	the novel soft gel-type dysphagia food	2242:2279	the novel soft gel-type dysphagia food	2242:2279	These findings provide insights for the development of the novel soft gel-type dysphagia food.					
36737943	5	65	theme	composite	1179:1187	arg1	gels					1189:1192	calcium salts-induced composite gels	1157:1192	calcium salts-induced composite gels	1157:1192	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	11	66	theme	novel	2246:2250	arg1	food					2276:2279	the novel soft gel-type dysphagia food	2242:2279	the novel soft gel-type dysphagia food	2242:2279	These findings provide insights for the development of the novel soft gel-type dysphagia food.					
36737943	8	67	theme	highest	1653:1659	arg1	capacity					1675:1682	the highest water-holding capacity	1649:1682	the highest water-holding capacity	1649:1682	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	2	68	dep	salts	508:512	arg1	10					515:516	10	515:516	10	515:516	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	68	dep	salts	508:512	arg1	30					519:520	30	519:520	30	519:520	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	68	dep	salts	508:512	arg1	50 mmol/L					527:535	50 mmol/L	527:535	50 mmol/L	527:535	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	4	69	theme	aggregates	1108:1117	arg1	formation					1089:1097	the formation	1085:1097	the formation of large aggregates	1085:1117	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	4	69	theme	aggregates	1108:1117	arg1	network					1134:1140	a weak gel network	1123:1140	a weak gel network	1123:1140	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	10	70	theme	level	2059:2063	arg1	diet					2099:2102	level 6 (soft and bite-sized) dysphagia diet	2059:2102	level 6 (soft and bite-sized) dysphagia diet	2059:2102	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	1	71	theme	lactate	162:168	arg1	Effects					119:125	Effects	119:125	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	119:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	2	72	theme	magnetic	573:580	arg1	resonance					582:590	low-field nuclear magnetic resonance	555:590	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	73	theme	laser	723:727	arg1	microscopy					738:747	confocal laser scanning microscopy	714:747	confocal laser scanning microscopy	714:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	74	theme	low-field	555:563	arg1	resonance					582:590	low-field nuclear magnetic resonance	555:590	low-field nuclear magnetic resonance measurement	555:602	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	9	75	theme	obvious	1875:1881	arg1	structure					1892:1900	the obvious lamellar structure	1871:1900	the obvious lamellar structure within the network	1871:1919	The gels adding CDP presented lower hardness and gumminess due to the obvious lamellar structure within the network.					
36737943	7	76	theme	wall	1597:1600	arg1	thickness					1602:1610	the decreased wall thickness	1583:1610	the decreased wall thickness	1583:1610	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	4	77	theme	Calcium	895:901	arg1	salts					903:907	Calcium salts	895:907	Calcium salts	895:907	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	10	78	theme	dysphagia	2089:2097	arg1	diet					2099:2102	level 6 (soft and bite-sized) dysphagia diet	2059:2102	level 6 (soft and bite-sized) dysphagia diet	2059:2102	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	6	79	theme	various	1309:1315	arg1	impacts					1317:1323	various impacts	1309:1323	various impacts	1309:1323	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	7	80	contain	possessed	1508:1516	arg1	gels					1430:1433	the gels	1426:1433	the gels containing CG	1426:1447	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	7	80	contain	possessed	1508:1516	arg2	network					1540:1546	an irregular cellular network	1518:1546	an irregular cellular network	1518:1546	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	10	81	theme	standardization	1951:1965	arg1	IDDSI					1979:1983	IDDSI	1979:1983	IDDSI	1979:1983	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	81	theme	standardization	1951:1965	arg1	initiative					1967:1976	International dysphagia diet standardization initiative	1922:1976	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	82	theme	dysphagia	1936:1944	arg1	IDDSI					1979:1983	IDDSI	1979:1983	IDDSI	1979:1983	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	82	theme	dysphagia	1936:1944	arg1	initiative					1967:1976	International dysphagia diet standardization initiative	1922:1976	International dysphagia diet standardization initiative (IDDSI) tests	1922:1990	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	6	83	theme	different	1281:1289	arg1	salts					1299:1303	different calcium salts	1281:1303	different calcium salts	1281:1303	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	1	84	theme	gluconate	138:146	arg1	Effects					119:125	Effects	119:125	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels	119:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	7	85	theme	increased	1557:1565	arg1	number					1572:1577	the increased pore number	1553:1577	the increased pore number	1553:1577	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	4	86	theme	gel	1130:1132	arg1	network					1134:1140	a weak gel network	1123:1140	a weak gel network	1123:1140	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	3	87	theme	various	793:799	arg1	properties					810:819	various soft gel properties	793:819	various soft gel properties	793:819	Results showed that calcium salts imparted various soft gel properties to the composite gels by influencing the interactions between MBS and FP.					
36737943	0	88	theme	composite	85:93	arg1	gels					95:98	protein composite gels	77:98	protein composite gels	77:98	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	1	89	theme	dysphagia	380:388	arg1	food					390:393	dysphagia food	380:393	dysphagia food	380:393	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	3	90	theme	composite	828:836	arg1	gels					838:841	the composite gels	824:841	the composite gels	824:841	Results showed that calcium salts imparted various soft gel properties to the composite gels by influencing the interactions between MBS and FP.					
36737943	2	91	theme	MBS-FP	461:466	arg1	gels					478:481	MBS-FP composite gels	461:481	MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	461:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	2	92	theme	electron	690:697	arg1	microscopy					699:708	scanning electron microscopy	681:708	scanning electron microscopy	681:708	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	1	93	theme	protein	293:299	arg1	gels					316:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	7	94	theme	cellular	1531:1538	arg1	network					1540:1546	an irregular cellular network	1518:1546	an irregular cellular network	1518:1546	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	6	95	theme	due	1347:1349	arg1	properties					1336:1345	the gel properties	1328:1345	the gel properties due to their diverse ability forming hydrogen bonds	1328:1397	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	1	96	theme	FP	302:303	arg1	gels					316:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	2	97	theme	different	490:498	arg1	salts					508:512	different calcium salts	490:512	different calcium salts (10, 30, and 50 mmol/L)	490:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	11	98	theme	food	2276:2279	arg1	development					2227:2237	the development	2223:2237	the development of the novel soft gel-type dysphagia food	2223:2279	These findings provide insights for the development of the novel soft gel-type dysphagia food.					
36737943	3	99	theme	gel	806:808	arg1	properties					810:819	various soft gel properties	793:819	various soft gel properties	793:819	Results showed that calcium salts imparted various soft gel properties to the composite gels by influencing the interactions between MBS and FP.					
36737943	6	100	theme	gel	1332:1334	arg1	properties					1336:1345	the gel properties	1328:1345	the gel properties due to their diverse ability forming hydrogen bonds	1328:1397	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	1	101	theme	composite	306:314	arg1	gels					316:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	mung bean starch (MBS)-flaxseed protein (FP) composite gels	261:319	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	8	102	theme	gel	1771:1773	arg1	network					1775:1781	the compact gel network	1759:1781	the compact gel network with larger cavities	1759:1802	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	2	103	theme	gels	478:481	arg1	properties					447:456	The water-immobilizing, rheological and structural properties	396:456	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L)	396:536	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	0	104	theme	calcium	29:35	arg1	bean					56:59	calcium salts-induced mung bean	29:59	calcium salts-induced mung bean	29:59	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	9	105	dep	lower	1835:1839	arg1	gumminess					1854:1862	gumminess	1854:1862	gumminess	1854:1862	The gels adding CDP presented lower hardness and gumminess due to the obvious lamellar structure within the network.					
36737943	9	105	dep	lower	1835:1839	arg1	hardness					1841:1848	hardness	1841:1848	hardness	1841:1848	The gels adding CDP presented lower hardness and gumminess due to the obvious lamellar structure within the network.					
36737943	2	106	dep	transform	648:656	arg1	infrared					658:665	infrared	658:665	transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy	648:747	The water-immobilizing, rheological and structural properties of MBS-FP composite gels adding different calcium salts (10, 30, and 50 mmol/L) were analyzed by low-field nuclear magnetic resonance measurement, rheological and textural analyses, fourier transform infrared spectroscopy, scanning electron microscopy and confocal laser scanning microscopy.					
36737943	0	107	theme	mung	51:54	arg1	bean					56:59	calcium salts-induced mung bean	29:59	calcium salts-induced mung bean	29:59	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	5	108	theme	salts-induced	1165:1177	arg1	gels					1189:1192	calcium salts-induced composite gels	1157:1192	calcium salts-induced composite gels	1157:1192	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36737943	1	109	theme	dihydrogen	187:196	arg1	CDP					209:211	CDP	209:211	CDP	209:211	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	1	109	theme	dihydrogen	187:196	arg1	phosphate					198:206	calcium dihydrogen phosphate	179:206	calcium dihydrogen phosphate (CDP)	179:212	Effects of calcium gluconate (CG), calcium lactate (CL) and calcium dihydrogen phosphate (CDP) on the structural and functional properties of mung bean starch (MBS)-flaxseed protein (FP) composite gels were investigated to explore the feasibility of developing dysphagia food.					
36737943	6	110	theme	hydrogen	1384:1391	arg1	bonds					1393:1397	hydrogen bonds	1384:1397	hydrogen bonds	1384:1397	In particular, different calcium salts had various impacts on the gel properties due to their diverse ability forming hydrogen bonds.					
36737943	0	111	theme	protein	77:83	arg1	gels					95:98	protein composite gels	77:98	protein composite gels	77:98	Textural characterization of calcium salts-induced mung bean starch-flaxseed protein composite gels as dysphagia food.					
36737943	4	112	theme	FP	988:989	arg1	molecules					991:999	FP molecules	988:999	FP molecules	988:999	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	8	113	theme	containing	1621:1630	arg1	CL					1642:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL	1613:1643	The gel containing 50 mmol/L CL had the highest water-holding capacity, in all the gels tested, by retaining more immobilized and mobile water in the compact gel network with larger cavities.					
36737943	4	114	theme	protein	1052:1058	arg1	aggregates					1060:1069	protein aggregates	1052:1069	protein aggregates	1052:1069	Calcium salts could affect the conformation of amylose chains, accelerate the aggregation of FP molecules, and increase the cross-linking between starch and protein aggregates, resulting in the formation of large aggregates and a weak gel network.					
36737943	7	115	theme	viscoelastic	1470:1481	arg1	moduli					1483:1488	the higher viscoelastic moduli	1459:1488	the higher viscoelastic moduli	1459:1488	Compared with CL and CDP, the gels containing CG presented the higher viscoelastic moduli and hardness, and possessed an irregular cellular network with the increased pore number and the decreased wall thickness.					
36737943	10	116	dep	level	2059:2063	arg1	bite-sized					2077:2086	bite-sized	2077:2086	bite-sized	2077:2086	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	10	116	dep	level	2059:2063	arg1	soft					2068:2071	soft	2068:2071	soft	2068:2071	International dysphagia diet standardization initiative (IDDSI) tests indicated that the gels adding CG and CL could be categorized into level 6 (soft and bite-sized) dysphagia diet, while the samples adding CDP could be classified into level 5 (minced and moist).					
36737943	5	117	theme	gel	1231:1233	arg1	strength					1235:1242	gel strength	1231:1242	gel strength	1231:1242	Consequently, calcium salts-induced composite gels showed lower viscoelastic moduli and gel strength than the control gel.					
36354078	0	0	theme	layer-by-layer	76:89	arg1	method					105:110	a layer-by-layer spray coating method	74:110	a layer-by-layer spray coating method	74:110	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	4	1	theme	water	955:959	arg1	test					966:969	water drop test	955:969	water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°	955:1076	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	2	2	theme	molecular	400:408	arg1	MD					420:421	MD	420:421	MD	420:421	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	2	2	theme	molecular	400:408	arg1	dynamics					410:417	molecular dynamics	400:417	A molecular dynamics (MD) simulation study	398:439	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	1	3	theme	PDMS-ZnO	340:347	arg1	hydrophobicity					368:381	PDMS-ZnO composite imparted hydrophobicity	340:381	PDMS-ZnO composite imparted hydrophobicity to the fabric	340:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	1	4	theme	two-step	166:173	arg1	spray					190:194	a two-step layer-by-layer spray	164:194	a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric	164:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	1	5	with	one	331:333	arg1	hydrophobicity					368:381	PDMS-ZnO composite imparted hydrophobicity	340:381	PDMS-ZnO composite imparted hydrophobicity to the fabric	340:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	0	6	theme	coating	97:103	arg1	method					105:110	a layer-by-layer spray coating method	74:110	a layer-by-layer spray coating method	74:110	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	1	7	theme	composite	349:357	arg1	hydrophobicity					368:381	PDMS-ZnO composite imparted hydrophobicity	340:381	PDMS-ZnO composite imparted hydrophobicity to the fabric	340:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	4	8	theme	coated	926:931	arg1	fabric					933:938	coated fabric	926:938	coated fabric	926:938	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	0	9	theme	spray	91:95	arg1	method					105:110	a layer-by-layer spray coating method	74:110	a layer-by-layer spray coating method	74:110	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	1	10	theme	imparted	359:366	arg1	hydrophobicity					368:381	PDMS-ZnO composite imparted hydrophobicity	340:381	PDMS-ZnO composite imparted hydrophobicity to the fabric	340:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	2	11	theme	layers	576:581	arg1	sequencing					550:559	the sequencing	546:559	the sequencing of the coating layers	546:581	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	3	12	dep	7 cm	808:811	arg1	to					805:806	to	805:806	to	805:806	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	4	13	theme	148°	1021:1024	arg1	angle					1012:1016	a contact angle	1002:1016	a contact angle of 148° for up to 120 s	1002:1040	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	3	14	theme	total	841:845	arg1	rate					860:863	total heat release rate	841:863	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	15	theme	char	782:785	arg1	length					787:792	char length	782:792	char length from 30 cm to 7 cm	782:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	2	16	dep	calculate	460:468	arg1	based					531:535	based	531:535	based on which the sequencing of the coating layers was determined and used to prepare coated samples	531:631	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	2	17	theme	coated	618:623	arg1	samples					625:631	coated samples	618:631	coated samples	618:631	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	3	18	from	decrease	820:827	arg1	values					865:870	total heat release rate values	841:870	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	18	from	decrease	820:827	arg1	7 cm					808:811	7 cm	808:811	7 cm	808:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	18	from	decrease	820:827	arg1	peak					832:835	peak	832:835	peak	832:835	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	18	from	decrease	820:827	arg1	LOI					733:735	LOI	733:735	LOI from 18 % in control to 30 %	733:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	18	from	decrease	820:827	arg1	length					787:792	char length	782:792	char length from 30 cm to 7 cm	782:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	18	from	decrease	820:827	arg1	%					745:745	18 %	742:745	18 % in control	742:756	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	19	theme	heat	847:850	arg1	rate					860:863	total heat release rate	841:863	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	1	20	theme	layer-by-layer	175:188	arg1	spray					190:194	a two-step layer-by-layer spray	164:194	a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric	164:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	2	21	theme	interfacial	470:480	arg1	adhesion					482:489	interfacial adhesion	470:489	interfacial adhesion of different components of the coating	470:528	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	4	22	theme	fabric	933:938	arg1	hydrophobicity					908:921	The hydrophobicity	904:921	The hydrophobicity of coated fabric	904:938	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	1	23	with	retardancy	304:313	arg1	hydrophobicity					368:381	PDMS-ZnO composite imparted hydrophobicity	340:381	PDMS-ZnO composite imparted hydrophobicity to the fabric	340:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	1	24	dep	phytate	282:288	arg1	provided					290:297	provided	290:297	phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric	282:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	2	25	used	used	602:605	arg2	sequencing					550:559	the sequencing	546:559	the sequencing of the coating layers	546:581	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	3	26	from	%	745:745	arg1	decrease					820:827	a decrease	818:827	a decrease in peak and total heat release rate values	818:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	26	from	%	745:745	arg1	LOI					733:735	LOI	733:735	LOI from 18 % in control to 30 %	733:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	26	from	%	745:745	arg1	reduction					769:777	a reduction	767:777	a reduction in char length from 30 cm to 7 cm	767:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	26	from	%	745:745	arg1	increase					721:728	an increase	718:728	an increase in LOI from 18 % in control to 30 %	718:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	26	from	%	745:745	arg1	control					750:756	control	750:756	control	750:756	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	27	from	improvement	679:689	arg1	retardancy					699:708	fire retardancy	694:708	fire retardancy	694:708	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	0	28	theme	fire	28:31	arg1	coating					43:49	hydrophobic fire retardant coating	16:49	hydrophobic fire retardant coating	16:49	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	3	29	from	7 cm	808:811	arg1	decrease					820:827	a decrease	818:827	a decrease in peak and total heat release rate values	818:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	29	from	7 cm	808:811	arg1	length					787:792	char length	782:792	char length from 30 cm to 7 cm	782:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	29	from	7 cm	808:811	arg1	reduction					769:777	a reduction	767:777	a reduction in char length from 30 cm to 7 cm	767:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	29	from	7 cm	808:811	arg1	increase					721:728	an increase	718:728	an increase in LOI from 18 % in control to 30 %	718:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	4	30	theme	contact	1004:1010	arg1	angle					1012:1016	a contact angle	1002:1016	a contact angle of 148° for up to 120 s	1002:1040	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	0	31	theme	hydrophobic	16:26	arg1	coating					43:49	hydrophobic fire retardant coating	16:49	hydrophobic fire retardant coating	16:49	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	1	32	theme	fire	299:302	arg1	retardancy					304:313	fire retardancy	299:313	fire retardancy	299:313	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	3	33	theme	release	852:858	arg1	rate					860:863	total heat release rate	841:863	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	0	34	theme	coating	43:49	arg1	Construction					0:11	Construction	0:11	Construction of hydrophobic fire retardant coating on cotton fabric	0:66	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	3	35	theme	coated	638:643	arg1	fabric					645:650	The coated fabric	634:650	The coated fabric	634:650	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	36	theme	rate	860:863	arg1	values					865:870	total heat release rate values	841:870	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	0	37	theme	retardant	33:41	arg1	coating					43:49	hydrophobic fire retardant coating	16:49	hydrophobic fire retardant coating	16:49	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	3	38	from	increase	721:728	arg1	values					865:870	total heat release rate values	841:870	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	38	from	increase	721:728	arg1	7 cm					808:811	7 cm	808:811	7 cm	808:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	38	from	increase	721:728	arg1	peak					832:835	peak	832:835	peak	832:835	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	38	from	increase	721:728	arg1	LOI					733:735	LOI	733:735	LOI from 18 % in control to 30 %	733:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	38	from	increase	721:728	arg1	length					787:792	char length	782:792	char length from 30 cm to 7 cm	782:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	38	from	increase	721:728	arg1	%					745:745	18 %	742:745	18 % in control	742:756	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	1	39	theme	first	222:226	arg1	layer					228:232	the first layer	218:232	the first layer of the coating comprising chitosan and ammonium	218:280	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	0	40	theme	cotton	54:59	arg1	fabric					61:66	cotton fabric	54:66	cotton fabric	54:66	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	2	41	theme	coating	568:574	arg1	layers					576:581	the coating layers	564:581	the coating layers	564:581	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	2	42	theme	coating	522:528	arg1	components					504:513	different components	494:513	different components of the coating	494:528	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	1	43	theme	Multifunctional	113:127	arg1	fabric					136:141	Multifunctional cotton fabric	113:141	Multifunctional cotton fabric	113:141	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	0	44	from	Construction	0:11	arg1	fabric					61:66	cotton fabric	54:66	cotton fabric	54:66	Construction of hydrophobic fire retardant coating on cotton fabric using a layer-by-layer spray coating method.					
36354078	1	45	theme	cotton	129:134	arg1	fabric					136:141	Multifunctional cotton fabric	113:141	Multifunctional cotton fabric	113:141	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	1	46	theme	second	324:329	arg1	one					331:333	the second one	320:333	the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric	320:395	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
36354078	3	47	theme	significant	667:677	arg1	improvement					679:689	a significant improvement	665:689	a significant improvement in fire retardancy	665:708	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	4	48	theme	coated	977:982	arg1	sample					984:989	coated sample	977:989	coated sample	977:989	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	3	49	from	reduction	769:777	arg1	values					865:870	total heat release rate values	841:870	total heat release rate values	841:870	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	49	from	reduction	769:777	arg1	7 cm					808:811	7 cm	808:811	7 cm	808:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	49	from	reduction	769:777	arg1	peak					832:835	peak	832:835	peak	832:835	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	49	from	reduction	769:777	arg1	LOI					733:735	LOI	733:735	LOI from 18 % in control to 30 %	733:764	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	49	from	reduction	769:777	arg1	length					787:792	char length	782:792	char length from 30 cm to 7 cm	782:811	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	3	49	from	reduction	769:777	arg1	%					745:745	18 %	742:745	18 % in control	742:756	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	2	50	theme	components	504:513	arg1	adhesion					482:489	interfacial adhesion	470:489	interfacial adhesion of different components of the coating	470:528	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	2	51	theme	dynamics	410:417	arg1	simulation					424:433	A molecular dynamics (MD) simulation	398:433	A molecular dynamics (MD) simulation study	398:439	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	2	52	theme	different	494:502	arg1	components					504:513	different components	494:513	different components of the coating	494:528	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	3	53	theme	fire	694:697	arg1	retardancy					699:708	fire retardancy	694:708	fire retardancy	694:708	The coated fabric demonstrated a significant improvement in fire retardancy through an increase in LOI from 18 % in control to 30 %, a reduction in char length from 30 cm to 7 cm, and a decrease in peak and total heat release rate values by 75 % and 33 %, respectively.					
36354078	2	54	theme	simulation	424:433	arg1	study					435:439	A molecular dynamics (MD) simulation study	398:439	A molecular dynamics (MD) simulation study	398:439	A molecular dynamics (MD) simulation study was carried out to calculate interfacial adhesion of different components of the coating, based on which the sequencing of the coating layers was determined and used to prepare coated samples.					
36354078	4	55	theme	control	1053:1059	arg1	sample					1061:1066	the control sample	1049:1066	the control sample	1049:1066	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	4	56	theme	drop	961:964	arg1	test					966:969	water drop test	955:969	water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°	955:1076	The hydrophobicity of coated fabric was tested via water drop test where coated sample maintained a contact angle of 148° for up to 120 s, while the control sample showed 0°.					
36354078	1	57	theme	coating	241:247	arg1	layer					228:232	the first layer	218:232	the first layer of the coating comprising chitosan and ammonium	218:280	Multifunctional cotton fabric was prepared through a two-step layer-by-layer spray coating method, where the first layer of the coating comprising chitosan and ammonium phytate provided fire retardancy, and the second one with PDMS-ZnO composite imparted hydrophobicity to the fabric.					
35064647	5	0	theme	uptake	734:739	arg1	capacity					741:748	suitable water uptake capacity	719:748	suitable water uptake capacity	719:748	The bilayer sheets are displayed suitable water uptake capacity and high stability in water.					
35064647	6	1	theme	degradation	865:875	arg1	weeks					852:856	three weeks	846:856	three weeks of PBS degradation	846:875	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	8	2	theme	endothelial	1123:1133	arg1	cells					1135:1139	human dermal microvascular endothelial cells	1096:1139	human dermal microvascular endothelial cells	1096:1139	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	8	3	theme	dermal	1102:1107	arg1	cells					1135:1139	human dermal microvascular endothelial cells	1096:1139	human dermal microvascular endothelial cells	1096:1139	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	6	4	theme	PBS	861:863	arg1	degradation					865:875	PBS degradation	861:875	PBS degradation	861:875	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	9	5	theme	vessel	1447:1452	arg1	ingrowth					1454:1461	blood vessel ingrowth	1441:1461	blood vessel ingrowth	1441:1461	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	6	6	theme	mass	783:786	arg1	%					837:837	≈50%	834:837	≈50%	834:837	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	6	6	theme	mass	783:786	arg1	percentage					798:807	The mass retention percentage	779:807	The mass retention percentage of the bilayer sheets	779:829	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	9	7	theme	dermal	1232:1237	arg1	regeneration					1239:1250	dermal regeneration	1232:1250	dermal regeneration	1232:1250	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	9	8	theme	faster	1203:1208	arg1	epithelialization					1210:1226	superior and faster epithelialization	1190:1226	superior and faster epithelialization	1190:1226	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	0	9	theme	Wound	102:106	arg1	Healing					108:114	Full-Thickness Wound Healing	87:114	Full-Thickness Wound Healing	87:114	A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full-Thickness Wound Healing.					
35064647	7	10	theme	bilayer	915:921	arg1	sheets					923:928	the bilayer sheets	911:928	the bilayer sheets	911:928	The tensile strength of the bilayer sheets is significantly increased from 13.41 ± 3.75 kPa (single scaffold) to 59.81 ± 5.98 kPa.					
35064647	2	11	theme	hierarchy	303:311	arg1	structure					313:321	skin hierarchy structure	298:321	skin hierarchy structure	298:321	In this study, a bilayer sheet originating from biological macromolecules, mimicking skin hierarchy structure is developed.					
35064647	4	12	theme	composite	624:632	arg1	layer					643:647	the composite scaffold layer	620:647	the composite scaffold layer with interconnected pores (≈150 µm)	620:683	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	13	theme	top	574:576	arg1	layer					578:582	the top layer	570:582	the top layer	570:582	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	3	14	theme	silk	372:375	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	9	15	theme	in	1165:1166	arg1	results					1157:1163	The experiment results	1142:1163	The experiment results in vivo	1142:1171	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	2	16	theme	skin	298:301	arg1	structure					313:321	skin hierarchy structure	298:321	skin hierarchy structure	298:321	In this study, a bilayer sheet originating from biological macromolecules, mimicking skin hierarchy structure is developed.					
35064647	9	17	theme	extracellular	1416:1428	arg1	matrix					1430:1435	the extracellular matrix	1412:1435	the extracellular matrix	1412:1435	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	3	18	theme	SA	469:470	arg1	film					472:475	a SA film	467:475	a SA film as the protective top layer	467:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	8	19	theme	human	1096:1100	arg1	cells					1135:1139	human dermal microvascular endothelial cells	1096:1139	human dermal microvascular endothelial cells	1096:1139	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	9	20	theme	blood	1441:1445	arg1	ingrowth					1454:1461	blood vessel ingrowth	1441:1461	blood vessel ingrowth	1441:1461	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	1	21	theme	acute	182:186	arg1	healing					204:210	acute cutaneous wound healing	182:210	acute cutaneous wound healing	182:210	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	9	22	theme	inflammatory	1355:1366	arg1	response					1368:1375	the inflammatory response	1351:1375	the inflammatory response	1351:1375	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	1	23	theme	cutaneous	188:196	arg1	healing					204:210	acute cutaneous wound healing	182:210	acute cutaneous wound healing	182:210	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	0	24	theme	Biomimetic	2:11	arg1	Dressing					31:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full-Thickness Wound Healing.					
35064647	7	25	theme	tensile	891:897	arg1	strength					899:906	The tensile strength	887:906	The tensile strength of the bilayer sheets	887:928	The tensile strength of the bilayer sheets is significantly increased from 13.41 ± 3.75 kPa (single scaffold) to 59.81 ± 5.98 kPa.					
35064647	9	26	theme	superior	1190:1197	arg1	epithelialization					1210:1226	superior and faster epithelialization	1190:1226	superior and faster epithelialization	1190:1226	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	1	27	theme	wound	198:202	arg1	healing					204:210	acute cutaneous wound healing	182:210	acute cutaneous wound healing	182:210	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	9	28	theme	wound	1328:1332	arg1	closure					1334:1340	wound closure	1328:1340	wound closure	1328:1340	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	0	29	theme	Bilayer	23:29	arg1	Dressing					31:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full-Thickness Wound Healing.					
35064647	8	30	theme	microvascular	1109:1121	arg1	cells					1135:1139	human dermal microvascular endothelial cells	1096:1139	human dermal microvascular endothelial cells	1096:1139	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	5	31	theme	bilayer	690:696	arg1	sheets					698:703	The bilayer sheets	686:703	The bilayer sheets	686:703	The bilayer sheets are displayed suitable water uptake capacity and high stability in water.					
35064647	3	32	theme	composite	411:419	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	3	33	theme	fibroin	377:383	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	4	34	theme	microscope	524:533	arg1	analysis					535:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	9	35	theme	experiment	1146:1155	arg1	results					1157:1163	The experiment results	1142:1163	The experiment results in vivo	1142:1171	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	3	36	theme	regenerative	444:455	arg1	layer					457:461	the bottom regenerative layer	433:461	the bottom regenerative layer	433:461	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	0	37	theme	Composite	13:21	arg1	Dressing					31:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing	0:38	A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full-Thickness Wound Healing.					
35064647	4	38	with	layer	643:647	arg1	pores					669:673	interconnected pores	654:673	interconnected pores (≈150 µm)	654:683	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	38	with	layer	643:647	arg1	≈150 µm					676:682	≈150 µm	676:682	≈150 µm	676:682	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	39	theme	interconnected	654:667	arg1	pores					669:673	interconnected pores	654:673	interconnected pores (≈150 µm)	654:683	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	39	theme	interconnected	654:667	arg1	≈150 µm					676:682	≈150 µm	676:682	≈150 µm	676:682	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	9	40	from	synthesis	1399:1407	arg1	matrix					1430:1435	the extracellular matrix	1412:1435	the extracellular matrix	1412:1435	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	9	40	from	synthesis	1399:1407	arg1	ingrowth					1454:1461	blood vessel ingrowth	1441:1461	blood vessel ingrowth	1441:1461	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	4	41	theme	scaffold	634:641	arg1	layer					643:647	the composite scaffold layer	620:647	the composite scaffold layer with interconnected pores (≈150 µm)	620:683	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	3	42	theme	SA	407:408	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	5	43	theme	high	754:757	arg1	stability					759:767	high stability	754:767	high stability	754:767	The bilayer sheets are displayed suitable water uptake capacity and high stability in water.					
35064647	6	44	theme	sheets	824:829	arg1	%					837:837	≈50%	834:837	≈50%	834:837	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	6	44	theme	sheets	824:829	arg1	percentage					798:807	The mass retention percentage	779:807	The mass retention percentage of the bilayer sheets	779:829	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	2	45	theme	bilayer	230:236	arg1	sheet					238:242	a bilayer sheet	228:242	a bilayer sheet originating from biological macromolecules, mimicking skin hierarchy structure	228:321	In this study, a bilayer sheet originating from biological macromolecules, mimicking skin hierarchy structure is developed.					
35064647	3	46	theme	bottom	437:442	arg1	layer					457:461	the bottom regenerative layer	433:461	the bottom regenerative layer	433:461	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	3	47	theme	/sodium	389:395	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	3	48	theme	steady	365:370	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	8	49	theme	composite	1022:1030	arg1	conducive					1051:1059	conducive	1051:1059	conducive	1051:1059	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	8	49	theme	composite	1022:1030	arg1	scaffolds					1032:1040	The composite scaffolds	1018:1040	The composite scaffolds	1018:1040	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	6	50	theme	bilayer	816:822	arg1	sheets					824:829	the bilayer sheets	812:829	the bilayer sheets	812:829	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	7	51	theme	single	980:985	arg1	13.41 ± 3.75 kPa					962:977	13.41 ± 3.75 kPa	962:977	13.41 ± 3.75 kPa (single scaffold)	962:995	The tensile strength of the bilayer sheets is significantly increased from 13.41 ± 3.75 kPa (single scaffold) to 59.81 ± 5.98 kPa.					
35064647	7	51	theme	single	980:985	arg1	scaffold					987:994	single scaffold	980:994	single scaffold	980:994	The tensile strength of the bilayer sheets is significantly increased from 13.41 ± 3.75 kPa (single scaffold) to 59.81 ± 5.98 kPa.					
35064647	1	52	theme	Full-thickness	117:130	arg1	dressings					143:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	3	53	theme	alginate	397:404	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	4	54	theme	electron	515:522	arg1	analysis					535:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	1	55	theme	skin	132:135	arg1	dressings					143:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	9	56	dep	in	1165:1166	arg1	vivo					1168:1171	vivo	1168:1171	vivo	1168:1171	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	4	57	theme	Scanning	506:513	arg1	analysis					535:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis	506:542	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	1	58	theme	wound	137:141	arg1	dressings					143:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings	117:151	Full-thickness skin wound dressings are critically important for acute cutaneous wound healing.					
35064647	8	59	theme	cells	1135:1139	arg1	growth					1068:1073	growth	1068:1073	growth	1068:1073	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	8	59	theme	cells	1135:1139	arg1	proliferation					1079:1091	proliferation	1079:1091	proliferation	1079:1091	The composite scaffolds are more conducive to the growth and proliferation of human dermal microvascular endothelial cells.					
35064647	2	60	theme	biological	261:270	arg1	macromolecules					272:285	biological macromolecules	261:285	biological macromolecules	261:285	In this study, a bilayer sheet originating from biological macromolecules, mimicking skin hierarchy structure is developed.					
35064647	3	61	theme	top	495:497	arg1	layer					499:503	the protective top layer	480:503	the protective top layer	480:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	4	62	theme	layer	578:582	arg1	adhered					609:615	adhered	609:615	adhered	609:615	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	62	theme	layer	578:582	arg1	thickness					557:565	the thickness	553:565	the thickness of the top layer	553:582	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	4	62	theme	layer	578:582	arg1	≈25 µm					587:592	≈25 µm	587:592	≈25 µm	587:592	Scanning electron microscope analysis revealed the thickness of the top layer is ≈25 µm and is tightly adhered to the composite scaffold layer with interconnected pores (≈150 µm).					
35064647	5	63	theme	suitable	719:726	arg1	capacity					741:748	suitable water uptake capacity	719:748	suitable water uptake capacity	719:748	The bilayer sheets are displayed suitable water uptake capacity and high stability in water.					
35064647	6	64	theme	retention	788:796	arg1	%					837:837	≈50%	834:837	≈50%	834:837	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	6	64	theme	retention	788:796	arg1	percentage					798:807	The mass retention percentage	779:807	The mass retention percentage of the bilayer sheets	779:829	The mass retention percentage of the bilayer sheets is ≈50% during three weeks of PBS degradation in vitro.					
35064647	3	65	theme	protective	484:493	arg1	layer					499:503	the protective top layer	480:503	the protective top layer	480:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	5	66	theme	water	728:732	arg1	capacity					741:748	suitable water uptake capacity	719:748	suitable water uptake capacity	719:748	The bilayer sheets are displayed suitable water uptake capacity and high stability in water.					
35064647	9	67	theme	bilayer	1278:1284	arg1	sheets					1286:1291	bilayer sheets	1278:1291	bilayer sheets	1278:1291	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	9	68	theme	protein	1391:1397	arg1	synthesis					1399:1407	protein synthesis	1391:1407	protein synthesis in the extracellular matrix and blood vessel ingrowth	1391:1461	The experiment results in vivo are demonstrated superior and faster epithelialization and dermal regeneration in the wound treated with bilayer sheets because the sheets are accelerated wound closure, reduced the inflammatory response, and promoted protein synthesis in the extracellular matrix and blood vessel ingrowth.					
35064647	7	69	theme	sheets	923:928	arg1	strength					899:906	The tensile strength	887:906	The tensile strength of the bilayer sheets	887:928	The tensile strength of the bilayer sheets is significantly increased from 13.41 ± 3.75 kPa (single scaffold) to 59.81 ± 5.98 kPa.					
35064647	3	70	theme	SF	386:387	arg1	scaffold					421:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold	363:428	a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer	363:503	This sheet is composed of a steady silk fibroin (SF)/sodium alginate (SA) composite scaffold as the bottom regenerative layer and a SA film as the protective top layer.					
35064647	0	71	theme	Full-Thickness	87:100	arg1	Healing					108:114	Full-Thickness Wound Healing	87:114	Full-Thickness Wound Healing	87:114	A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full-Thickness Wound Healing.					
35973253	6	0	theme	Fe3O4	1422:1426	arg1	electrode					1436:1444	the Fe3O4@AMC/RGO electrode	1418:1444	the Fe3O4@AMC/RGO electrode	1418:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	5	1	theme	@	1144:1144	arg1	composite					1153:1161	the Fe3O4@AMC/RGO composite	1135:1161	the Fe3O4@AMC/RGO composite	1135:1161	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	4	2	theme	hierarchical	1016:1027	arg1	structure					1029:1037	a unique hierarchical structure	1007:1037	a unique hierarchical structure	1007:1037	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	1	3	theme	amylose-derived	295:309	arg1	AMC					319:321	AMC	319:321	AMC	319:321	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	3	theme	amylose-derived	295:309	arg1	carbon					311:316	an amorphous amylose-derived carbon	282:316	an amorphous amylose-derived carbon (AMC)	282:322	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	4	4	theme	RGO	991:993	arg1	sheets					995:1000	the larger sized RGO sheets	974:1000	the larger sized RGO sheets	974:1000	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	5	theme	FeOOH	736:740	arg1	sample					749:754	the intermediate FeOOH@AM/RGO sample	719:754	the intermediate FeOOH@AM/RGO sample	719:754	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	3	6	from	size	850:853	arg1	composite					882:890	the final Fe3O4@AMC/RGO composite	858:890	the final Fe3O4@AMC/RGO composite	858:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	1	7	theme	magnetite	232:240	arg1	nanoparticles					250:262	magnetite (Fe3O4) nanoparticles	232:262	magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework	232:365	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	2	8	theme	small-sized	532:542	arg1	AMC					554:556	small-sized pyrolytic AMC	532:556	small-sized pyrolytic AMC in the following thermal treatment	532:591	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	4	9	theme	@	1071:1071	arg1	sample					1080:1085	the Fe3O4@AMC/RGO sample	1062:1085	the Fe3O4@AMC/RGO sample	1062:1085	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	7	10	contain	possesses	1491:1499	arg1	sample					1484:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	7	10	contain	possesses	1491:1499	arg2	potential					1506:1514	good potential	1501:1514	good potential for scaling-up and finding applications in wider fields	1501:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	2	11	theme	thermal	575:581	arg1	treatment					583:591	the following thermal treatment	561:591	the following thermal treatment	561:591	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	3	12	theme	AM/RGO	742:747	arg1	sample					749:754	the intermediate FeOOH@AM/RGO sample	719:754	the intermediate FeOOH@AM/RGO sample	719:754	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	5	13	theme	AMC/RGO	1145:1151	arg1	composite					1153:1161	the Fe3O4@AMC/RGO composite	1135:1161	the Fe3O4@AMC/RGO composite	1135:1161	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	7	14	theme	wider	1559:1563	arg1	fields					1565:1570	wider fields	1559:1570	wider fields	1559:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	2	15	theme	redox	485:489	arg1	system					507:512	the first mild redox coprecipitation system	470:512	the first mild redox coprecipitation system	470:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	5	16	theme	rate	1253:1256	arg1	performance					1258:1268	rate performance	1253:1268	rate performance	1253:1268	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	6	17	theme	AM	1351:1352	arg1	molecules					1354:1362	AM molecules	1351:1362	AM molecules	1351:1362	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	1	18	theme	straightforward	164:178	arg1	method					197:202	A straightforward and eco-friendly method	162:202	A straightforward and eco-friendly method	162:202	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	3	19	theme	Fe3O4	868:872	arg1	composite					882:890	the final Fe3O4@AMC/RGO composite	858:890	the final Fe3O4@AMC/RGO composite	858:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	2	20	theme	first	474:478	arg1	system					507:512	the first mild redox coprecipitation system	470:512	the first mild redox coprecipitation system	470:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	1	21	theme	eco-friendly	184:195	arg1	method					197:202	A straightforward and eco-friendly method	162:202	A straightforward and eco-friendly method	162:202	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	5	22	theme	superior	1222:1229	arg1	stability					1239:1247	superior cycling stability	1222:1247	superior cycling stability	1222:1247	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	0	23	theme	reduced	104:110	arg1	framework					127:135	reduced graphene oxide framework	104:135	reduced graphene oxide framework for lithium-ion storage	104:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	4	24	theme	AMC	935:937	arg1	result					898:903	a result	896:903	a result	896:903	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	4	24	theme	AMC	935:937	arg1	nanoparticles					917:929	Fe3O4 nanoparticles	911:929	Fe3O4 nanoparticles	911:929	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	4	24	theme	AMC	935:937	arg1	domains					939:945	AMC domains	935:945	AMC domains	935:945	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	0	25	theme	oxide	121:125	arg1	framework					127:135	reduced graphene oxide framework	104:135	reduced graphene oxide framework for lithium-ion storage	104:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	6	26	dep	sheets	1340:1345	arg1	GO					1337:1338	GO	1337:1338	GO	1337:1338	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	3	27	theme	AMC/RGO	874:880	arg1	composite					882:890	the final Fe3O4@AMC/RGO composite	858:890	the final Fe3O4@AMC/RGO composite	858:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	0	28	theme	Controllable	0:11	arg1	magnetite					25:33	Controllable engineering magnetite	0:33	Controllable engineering magnetite	0:33	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	5	29	theme	RGO	1123:1125	arg1	sample					1127:1132	the controlled Fe3O4@RGO sample	1102:1132	the controlled Fe3O4@RGO sample	1102:1132	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	2	30	theme	few-layered	435:445	arg1	oxide					456:460	few-layered graphene oxide	435:460	few-layered graphene oxide (GO) in the first mild redox coprecipitation system	435:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	6	31	theme	inspiring	1379:1387	arg1	behaviors					1405:1413	the inspiring electrochemical behaviors	1375:1413	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	7	32	theme	AMC/RGO	1476:1482	arg1	sample					1484:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	4	33	theme	sized	985:989	arg1	sheets					995:1000	the larger sized RGO sheets	974:1000	the larger sized RGO sheets	974:1000	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	34	theme	AM	629:630	arg1	molecules					632:640	the AM molecules	625:640	the AM molecules	625:640	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	5	35	theme	Fe3O4	1117:1121	arg1	sample					1127:1132	the controlled Fe3O4@RGO sample	1102:1132	the controlled Fe3O4@RGO sample	1102:1132	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	7	36	from	applications	1543:1554	arg1	fields					1565:1570	wider fields	1559:1570	wider fields	1559:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	7	37	theme	Fe3O4	1470:1474	arg1	sample					1484:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	3	38	theme	growth	673:678	arg1	kinetics					680:687	the crystal growth kinetics	661:687	the crystal growth kinetics for the akaganeite (FeOOH)	661:714	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	6	39	theme	electrode	1436:1444	arg1	behaviors					1405:1413	the inspiring electrochemical behaviors	1375:1413	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	6	39	theme	electrode	1436:1444	arg1	mechanisms					1299:1308	The mechanisms	1295:1308	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	5	40	theme	enhanced	1183:1190	arg1	efficiency					1210:1219	remarkably enhanced initial coulombic efficiency	1172:1219	remarkably enhanced initial coulombic efficiency	1172:1219	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	4	41	theme	unique	1009:1014	arg1	structure					1029:1037	a unique hierarchical structure	1007:1037	a unique hierarchical structure	1007:1037	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	5	42	theme	controlled	1106:1115	arg1	sample					1127:1132	the controlled Fe3O4@RGO sample	1102:1132	the controlled Fe3O4@RGO sample	1102:1132	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	6	43	theme	@	1427:1427	arg1	electrode					1436:1444	the Fe3O4@AMC/RGO electrode	1418:1444	the Fe3O4@AMC/RGO electrode	1418:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	5	44	theme	Fe3O4	1139:1143	arg1	composite					1153:1161	the Fe3O4@AMC/RGO composite	1135:1161	the Fe3O4@AMC/RGO composite	1135:1161	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	1	45	link	amylose-derived	295:309	arg1	AMC					319:321	AMC	319:321	AMC	319:321	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	45	link	amylose-derived	295:309	arg1	carbon					311:316	an amorphous amylose-derived carbon	282:316	an amorphous amylose-derived carbon (AMC)	282:322	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	46	theme	amorphous	285:293	arg1	AMC					319:321	AMC	319:321	AMC	319:321	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	46	theme	amorphous	285:293	arg1	carbon					311:316	an amorphous amylose-derived carbon	282:316	an amorphous amylose-derived carbon (AMC)	282:322	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	47	theme	graphene	336:343	arg1	RGO					352:354	RGO	352:354	RGO	352:354	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	1	47	theme	graphene	336:343	arg1	oxide					345:349	graphene oxide	336:349	reduced graphene oxide (RGO) framework	328:365	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	4	48	theme	Fe3O4	1066:1070	arg1	sample					1080:1085	the Fe3O4@AMC/RGO sample	1062:1085	the Fe3O4@AMC/RGO sample	1062:1085	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	49	theme	@	741:741	arg1	sample					749:754	the intermediate FeOOH@AM/RGO sample	719:754	the intermediate FeOOH@AM/RGO sample	719:754	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	0	50	theme	lithium-ion	141:151	arg1	storage					153:159	lithium-ion storage	141:159	lithium-ion storage	141:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	2	51	theme	pyrolytic	544:552	arg1	AMC					554:556	small-sized pyrolytic AMC	532:556	small-sized pyrolytic AMC in the following thermal treatment	532:591	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	4	52	theme	AMC/RGO	1072:1078	arg1	sample					1080:1085	the Fe3O4@AMC/RGO sample	1062:1085	the Fe3O4@AMC/RGO sample	1062:1085	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	53	theme	intermediate	723:734	arg1	sample					749:754	the intermediate FeOOH@AM/RGO sample	719:754	the intermediate FeOOH@AM/RGO sample	719:754	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	1	54	theme	oxide	345:349	arg1	framework					357:365	reduced graphene oxide (RGO) framework	328:365	reduced graphene oxide (RGO) framework	328:365	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	2	55	theme	following	565:573	arg1	treatment					583:591	the following thermal treatment	561:591	the following thermal treatment	561:591	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	5	56	theme	cycling	1231:1237	arg1	stability					1239:1247	superior cycling stability	1222:1247	superior cycling stability	1222:1247	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	3	57	theme	controlled	839:848	arg1	size					850:853	significantly controlled size	825:853	significantly controlled size in the final Fe3O4@AMC/RGO composite	825:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	7	58	theme	finding	1535:1541	arg1	applications					1543:1554	scaling-up and finding applications	1520:1554	scaling-up and finding applications in wider fields	1520:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	2	59	theme	mild	480:483	arg1	system					507:512	the first mild redox coprecipitation system	470:512	the first mild redox coprecipitation system	470:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	5	60	theme	coulombic	1200:1208	arg1	efficiency					1210:1219	remarkably enhanced initial coulombic efficiency	1172:1219	remarkably enhanced initial coulombic efficiency	1172:1219	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	3	61	with	transformation	782:795	arg1	size					850:853	significantly controlled size	825:853	significantly controlled size in the final Fe3O4@AMC/RGO composite	825:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	3	62	theme	@	873:873	arg1	composite					882:890	the final Fe3O4@AMC/RGO composite	858:890	the final Fe3O4@AMC/RGO composite	858:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	7	63	theme	scaling-up	1520:1529	arg1	applications					1543:1554	scaling-up and finding applications	1520:1554	scaling-up and finding applications in wider fields	1520:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	2	64	from	oxide	456:460	arg1	system					507:512	the first mild redox coprecipitation system	470:512	the first mild redox coprecipitation system	470:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	0	65	theme	graphene	112:119	arg1	framework					127:135	reduced graphene oxide framework	104:135	reduced graphene oxide framework for lithium-ion storage	104:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	3	66	theme	final	862:866	arg1	composite					882:890	the final Fe3O4@AMC/RGO composite	858:890	the final Fe3O4@AMC/RGO composite	858:890	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	4	67	theme	Fe3O4	911:915	arg1	result					898:903	a result	896:903	a result	896:903	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	4	67	theme	Fe3O4	911:915	arg1	nanoparticles					917:929	Fe3O4 nanoparticles	911:929	Fe3O4 nanoparticles	911:929	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	4	67	theme	Fe3O4	911:915	arg1	domains					939:945	AMC domains	935:945	AMC domains	935:945	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	68	theme	Fe3O4	800:804	arg1	nanoparticles					806:818	Fe3O4 nanoparticles	800:818	Fe3O4 nanoparticles	800:818	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	6	69	theme	interaction	1317:1327	arg1	behaviors					1405:1413	the inspiring electrochemical behaviors	1375:1413	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	6	69	theme	interaction	1317:1327	arg1	mechanisms					1299:1308	The mechanisms	1295:1308	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	2	70	theme	coprecipitation	491:505	arg1	system					507:512	the first mild redox coprecipitation system	470:512	the first mild redox coprecipitation system	470:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	0	71	theme	engineering	13:23	arg1	magnetite					25:33	Controllable engineering magnetite	0:33	Controllable engineering magnetite	0:33	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	2	72	dep	oxide	456:460	arg1	GO					463:464	GO	463:464	GO	463:464	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	2	73	theme	graphene	447:454	arg1	oxide					456:460	few-layered graphene oxide	435:460	few-layered graphene oxide (GO) in the first mild redox coprecipitation system	435:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	6	74	theme	electrochemical	1389:1403	arg1	behaviors					1405:1413	the inspiring electrochemical behaviors	1375:1413	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode	1295:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	3	75	theme	molecules	632:640	arg1	presence					613:620	the presence	609:620	the presence of the AM molecules	609:640	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	5	76	theme	lithium-ion	1274:1284	arg1	storage					1286:1292	lithium-ion storage	1274:1292	lithium-ion storage	1274:1292	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	2	77	theme	reducing	416:423	arg1	agent					425:429	reducing agent	416:429	reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system	416:512	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	7	78	theme	good	1501:1504	arg1	potential					1506:1514	good potential	1501:1514	good potential for scaling-up and finding applications in wider fields	1501:1570	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	0	79	theme	hierarchical	64:75	arg1	amylose					77:83	a hierarchical amylose	62:83	a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage	62:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	1	80	theme	reduced	328:334	arg1	framework					357:365	reduced graphene oxide (RGO) framework	328:365	reduced graphene oxide (RGO) framework	328:365	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	4	81	theme	larger	978:983	arg1	sheets					995:1000	the larger sized RGO sheets	974:1000	the larger sized RGO sheets	974:1000	As a result, both Fe3O4 nanoparticles and AMC domains are adjacently anchored on the larger sized RGO sheets, and a unique hierarchical structure has been engineered in the Fe3O4@AMC/RGO sample.					
35973253	3	82	theme	crystal	665:671	arg1	kinetics					680:687	the crystal growth kinetics	661:687	the crystal growth kinetics for the akaganeite (FeOOH)	661:714	In particular, the presence of the AM molecules effectively limits the crystal growth kinetics for the akaganeite (FeOOH) in the intermediate FeOOH@AM/RGO sample, which contributes to the transformation to Fe3O4 nanoparticles with significantly controlled size in the final Fe3O4@AMC/RGO composite.					
35973253	5	83	theme	@	1122:1122	arg1	sample					1127:1132	the controlled Fe3O4@RGO sample	1102:1132	the controlled Fe3O4@RGO sample	1102:1132	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35973253	7	84	theme	@	1475:1475	arg1	sample					1484:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample	1466:1489	The Fe3O4@AMC/RGO sample possesses good potential for scaling-up and finding applications in wider fields.					
35973253	0	85	dep	nanoparticles	35:47	arg1	dispersed					49:57	dispersed	49:57	nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage	35:159	Controllable engineering magnetite nanoparticles dispersed in a hierarchical amylose derived carbon and reduced graphene oxide framework for lithium-ion storage.					
35973253	1	86	theme	Fe3O4	243:247	arg1	nanoparticles					250:262	magnetite (Fe3O4) nanoparticles	232:262	magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework	232:365	A straightforward and eco-friendly method is demonstrated to engineer magnetite (Fe3O4) nanoparticles well dispersed by an amorphous amylose-derived carbon (AMC) and reduced graphene oxide (RGO) framework.					
35973253	2	87	from	AMC	554:556	arg1	treatment					583:591	the following thermal treatment	561:591	the following thermal treatment	561:591	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	2	88	theme	available	378:386	arg1	AM					397:398	AM	397:398	AM	397:398	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	2	88	theme	available	378:386	arg1	amylose					388:394	Naturally available amylose	368:394	Naturally available amylose (AM)	368:399	Naturally available amylose (AM) serves as both reducing agent for few-layered graphene oxide (GO) in the first mild redox coprecipitation system and precursor for small-sized pyrolytic AMC in the following thermal treatment.					
35973253	6	89	theme	AMC/RGO	1428:1434	arg1	electrode					1436:1444	the Fe3O4@AMC/RGO electrode	1418:1444	the Fe3O4@AMC/RGO electrode	1418:1444	The mechanisms of the interaction between GO sheets and AM molecules as well as the inspiring electrochemical behaviors of the Fe3O4@AMC/RGO electrode have been revealed.					
35973253	5	90	theme	initial	1192:1198	arg1	efficiency					1210:1219	remarkably enhanced initial coulombic efficiency	1172:1219	remarkably enhanced initial coulombic efficiency	1172:1219	Compared with the controlled Fe3O4@RGO sample, the Fe3O4@AMC/RGO composite exhibits remarkably enhanced initial coulombic efficiency, superior cycling stability and rate performance for lithium-ion storage.					
35318081	3	0	theme	multifunctional	359:373	arg1	hydrogels					385:393	multifunctional composite hydrogels	359:393	multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO)	359:492	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	1	1	theme	antitumor	194:202	arg1	applications					204:215	antitumor applications	194:215	antitumor applications	194:215	Biopolymer-based composite hydrogels have attracted tremendous attention for tissue regeneration and antitumor applications.					
35318081	8	2	dep	media	971:975	arg1	7.4					986:988	7.4	986:988	7.4	986:988	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	8	2	dep	media	971:975	arg1	8.4					995:997	8.4	995:997	8.4	995:997	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	8	3	theme	SGT-4	934:938	arg1	release					923:929	The drug release	914:929	The drug release of SGT-4	914:938	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	3	4	theme	composite	375:383	arg1	hydrogels					385:393	multifunctional composite hydrogels	359:393	multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO)	359:492	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	8	5	theme	release	1025:1031	arg1	kinetics					1008:1015	the kinetics	1004:1015	the kinetics of drug release	1004:1031	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	10	6	dep	anticancer	1247:1256	arg1	the					1243:1245	the	1243:1245	the	1243:1245	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	4	7	theme	morphological	617:629	arg1	results					631:637	The structural and morphological results	598:637	The structural and morphological results	598:637	The structural and morphological results show that the hydrogels exhibit the desired functionality and porosity.					
35318081	3	8	theme	tissue	415:420	arg1	capabilities					435:446	anticancer and tissue regeneration capabilities	400:446	capabilities	435:446	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	2	9	theme	side	334:337	arg1	effects					339:345	low side effects	330:345	low side effects	330:345	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	3	10	theme	regeneration	422:433	arg1	capabilities					435:446	anticancer and tissue regeneration capabilities	400:446	capabilities	435:446	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	9	11	theme	severe	1143:1148	arg1	agents					1161:1166	severe infectious agents	1143:1166	severe infectious agents	1143:1166	Antibacterial activities were evaluated against severe infectious agents.					
35318081	2	12	theme	low	330:332	arg1	effects					339:345	low side effects	330:345	low side effects	330:345	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	6	13	dep	aqueous	823:829	arg1	media					839:843	media	839:843	media	839:843	SGT-4 had the highest swelling in both aqueous and PBS media.					
35318081	10	14	theme	MC3T3-E1	1199:1206	arg1	lines					1214:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	3	15	theme	anticancer	400:409	arg1	capabilities					435:446	anticancer and tissue regeneration capabilities	400:446	capabilities	435:446	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	8	16	theme	drug	918:921	arg1	release					923:929	The drug release	914:929	The drug release of SGT-4	914:938	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	10	17	theme	hydrogels	1296:1304	arg1	anticancer					1247:1256	anticancer	1247:1256	anticancer	1247:1256	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	10	17	theme	hydrogels	1296:1304	arg1	biocompatibility					1262:1277	biocompatibility	1262:1277	biocompatibility	1262:1277	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	10	18	theme	U87	1178:1180	arg1	lines					1214:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	10	19	theme	composite	1286:1294	arg1	hydrogels					1296:1304	the composite hydrogels	1282:1304	the composite hydrogels	1282:1304	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	11	20	theme	tissue	1416:1421	arg1	regeneration					1423:1434	tissue regeneration	1416:1434	tissue regeneration	1416:1434	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	1	21	theme	Biopolymer-based	93:108	arg1	hydrogels					120:128	Biopolymer-based composite hydrogels	93:128	Biopolymer-based composite hydrogels	93:128	Biopolymer-based composite hydrogels have attracted tremendous attention for tissue regeneration and antitumor applications.					
35318081	11	22	theme	antitumor	1440:1448	arg1	applications					1450:1461	antitumor applications	1440:1461	antitumor applications	1440:1461	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	3	23	theme	sodium	449:454	arg1	SA					466:467	SA	466:467	SA	466:467	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	3	23	theme	sodium	449:454	arg1	alginate					456:463	sodium alginate	449:463	sodium alginate (SA)	449:468	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	1	24	theme	composite	110:118	arg1	hydrogels					120:128	Biopolymer-based composite hydrogels	93:128	Biopolymer-based composite hydrogels	93:128	Biopolymer-based composite hydrogels have attracted tremendous attention for tissue regeneration and antitumor applications.					
35318081	3	25	theme	graphene	474:481	arg1	oxide					483:487	graphene oxide	474:487	graphene oxide (GO)	474:492	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	0	26	theme	Sodium	0:5	arg1	composite					21:29	Sodium alginate-f-GO composite	0:29	Sodium alginate-f-GO composite	0:29	Sodium alginate-f-GO composite hydrogels for tissue regeneration and antitumor applications.					
35318081	8	27	theme	Higuchi	1065:1071	arg1	R2 = 0.93587					1080:1091	R2 = 0.93587	1080:1091	R2 = 0.93587	1080:1091	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	8	27	theme	Higuchi	1065:1071	arg1	model					1073:1077	the Higuchi model	1061:1077	the Higuchi model (R2 = 0.93587)	1061:1092	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	8	28	theme	drug	1020:1023	arg1	release					1025:1031	drug release	1020:1031	drug release	1020:1031	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	9	29	theme	Antibacterial	1095:1107	arg1	activities					1109:1118	Antibacterial activities	1095:1118	Antibacterial activities	1095:1118	Antibacterial activities were evaluated against severe infectious agents.					
35318081	11	30	used	used	1381:1384	arg2	hydrogels					1362:1370	the composite hydrogels	1348:1370	the composite hydrogels	1348:1370	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	11	30	used	used	1381:1384	arg2	biomaterials					1399:1410	potential biomaterials	1389:1410	potential biomaterials for tissue regeneration and antitumor applications	1389:1461	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	9	31	theme	infectious	1150:1159	arg1	agents					1161:1166	severe infectious agents	1143:1166	severe infectious agents	1143:1166	Antibacterial activities were evaluated against severe infectious agents.					
35318081	7	32	theme	hydrogel	881:888	arg1	biodegradation					859:872	biodegradation	859:872	biodegradation	859:872	Swelling and biodegradation of the hydrogel were inversely related.					
35318081	7	32	theme	hydrogel	881:888	arg1	Swelling					846:853	Swelling	846:853	Swelling	846:853	Swelling and biodegradation of the hydrogel were inversely related.					
35318081	5	33	theme	PBS	755:757	arg1	medium					759:764	an aqueous and PBS medium	740:764	an aqueous and PBS medium	740:764	The swelling of hydrogels in an aqueous and PBS medium was investigated.					
35318081	4	34	theme	desired	675:681	arg1	functionality					683:695	functionality	683:695	functionality	683:695	The structural and morphological results show that the hydrogels exhibit the desired functionality and porosity.					
35318081	0	35	theme	tissue	45:50	arg1	regeneration					52:63	tissue regeneration	45:63	tissue regeneration	45:63	Sodium alginate-f-GO composite hydrogels for tissue regeneration and antitumor applications.					
35318081	4	36	theme	structural	602:611	arg1	results					631:637	The structural and morphological results	598:637	The structural and morphological results	598:637	The structural and morphological results show that the hydrogels exhibit the desired functionality and porosity.					
35318081	2	37	theme	sodium	224:229	arg1	alginate					231:238	sodium alginate	224:238	sodium alginate	224:238	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	2	37	theme	sodium	224:229	arg1	biopolymer					245:254	a biopolymer	243:254	a biopolymer	243:254	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	2	38	theme	therapeutic	278:288	arg1	options					290:296	excellent therapeutic options	268:296	excellent therapeutic options with long-term drug release and low side effects	268:345	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	5	39	from	swelling	715:722	arg1	medium					759:764	an aqueous and PBS medium	740:764	an aqueous and PBS medium	740:764	The swelling of hydrogels in an aqueous and PBS medium was investigated.					
35318081	10	40	theme	cell	1209:1212	arg1	lines					1214:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	2	41	theme	excellent	268:276	arg1	options					290:296	excellent therapeutic options	268:296	excellent therapeutic options with long-term drug release and low side effects	268:345	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	8	42	theme	pH	968:969	arg1	media					971:975	different pH media	958:975	different pH media (pH 6.4, 7.4, and 8.4)	958:998	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	11	43	theme	composite	1352:1360	arg1	hydrogels					1362:1370	the composite hydrogels	1348:1370	the composite hydrogels	1348:1370	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	11	43	theme	composite	1352:1360	arg1	biomaterials					1399:1410	potential biomaterials	1389:1410	potential biomaterials for tissue regeneration and antitumor applications	1389:1461	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	2	44	with	options	290:296	arg1	release					318:324	long-term drug release	303:324	long-term drug release	303:324	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	2	44	with	options	290:296	arg1	effects					339:345	low side effects	330:345	low side effects	330:345	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	5	45	theme	hydrogels	727:735	arg1	swelling					715:722	The swelling	711:722	The swelling of hydrogels in an aqueous and PBS medium	711:764	The swelling of hydrogels in an aqueous and PBS medium was investigated.					
35318081	8	46	theme	different	958:966	arg1	media					971:975	different pH media	958:975	different pH media (pH 6.4, 7.4, and 8.4)	958:998	The drug release of SGT-4 was determined in different pH media (pH 6.4, 7.4, and 8.4) and the kinetics of drug release was determined according to the Higuchi model (R2 = 0.93587).					
35318081	1	47	theme	tremendous	145:154	arg1	attention					156:164	tremendous attention	145:164	tremendous attention	145:164	Biopolymer-based composite hydrogels have attracted tremendous attention for tissue regeneration and antitumor applications.					
35318081	6	48	contain	had	790:792	arg1	SGT-4					784:788	SGT-4	784:788	SGT-4	784:788	SGT-4 had the highest swelling in both aqueous and PBS media.					
35318081	6	48	contain	had	790:792	arg2	swelling					806:813	the highest swelling	794:813	the highest swelling	794:813	SGT-4 had the highest swelling in both aqueous and PBS media.					
35318081	10	49	theme	Uppsala	1169:1175	arg1	U87					1178:1180	Uppsala (U87)	1169:1181	Uppsala (U87)	1169:1181	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	6	50	theme	highest	798:804	arg1	swelling					806:813	the highest swelling	794:813	the highest swelling	794:813	SGT-4 had the highest swelling in both aqueous and PBS media.					
35318081	3	51	theme	tetraethyl	538:547	arg1	TEOS					564:567	TEOS	564:567	TEOS	564:567	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	3	51	theme	tetraethyl	538:547	arg1	orthosilicate					549:561	tetraethyl orthosilicate	538:561	tetraethyl orthosilicate (TEOS)	538:568	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	2	52	theme	drug	313:316	arg1	release					318:324	long-term drug release	303:324	long-term drug release	303:324	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	3	53	dep	oxide	483:487	arg1	GO					490:491	GO	490:491	GO	490:491	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	5	54	theme	aqueous	743:749	arg1	medium					759:764	an aqueous and PBS medium	740:764	an aqueous and PBS medium	740:764	The swelling of hydrogels in an aqueous and PBS medium was investigated.					
35318081	2	55	theme	long-term	303:311	arg1	release					318:324	long-term drug release	303:324	long-term drug release	303:324	Since sodium alginate is a biopolymer, they offer excellent therapeutic options with long-term drug release and low side effects.					
35318081	1	56	theme	tissue	170:175	arg1	regeneration					177:188	tissue regeneration	170:188	tissue regeneration	170:188	Biopolymer-based composite hydrogels have attracted tremendous attention for tissue regeneration and antitumor applications.					
35318081	10	57	theme	osteoblast	1187:1196	arg1	MC3T3-E1					1199:1206	osteoblast (MC3T3-E1)	1187:1207	osteoblast (MC3T3-E1)	1187:1207	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	11	58	theme	potential	1389:1397	arg1	hydrogels					1362:1370	the composite hydrogels	1348:1370	the composite hydrogels	1348:1370	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	11	58	theme	potential	1389:1397	arg1	biomaterials					1399:1410	potential biomaterials	1389:1410	potential biomaterials for tissue regeneration and antitumor applications	1389:1461	These results suggest that the composite hydrogels could be used as potential biomaterials for tissue regeneration and antitumor applications.					
35318081	3	59	with	hydrogels	385:393	arg1	SA					466:467	SA	466:467	SA	466:467	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	3	59	with	hydrogels	385:393	arg1	capabilities					435:446	anticancer and tissue regeneration capabilities	400:446	capabilities	435:446	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	3	59	with	hydrogels	385:393	arg1	alginate					456:463	sodium alginate	449:463	sodium alginate (SA)	449:468	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	3	59	with	hydrogels	385:393	arg1	oxide					483:487	graphene oxide	474:487	graphene oxide (GO)	474:492	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	10	60	used	used	1225:1228	arg2	lines					1214:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines	1169:1218	Uppsala (U87) and osteoblast (MC3T3-E1) cell lines were used to determine the anticancer and biocompatibility of the composite hydrogels, respectively.					
35318081	0	61	theme	antitumor	69:77	arg1	applications					79:90	antitumor applications	69:90	antitumor applications	69:90	Sodium alginate-f-GO composite hydrogels for tissue regeneration and antitumor applications.					
35318081	3	62	theme	solvothermal	577:588	arg1	method					590:595	the solvothermal method	573:595	the solvothermal method	573:595	To prepare multifunctional composite hydrogels with anticancer and tissue regeneration capabilities, sodium alginate (SA) and graphene oxide (GO) were covalently linked and crosslinked with tetraethyl orthosilicate (TEOS) by the solvothermal method.					
35318081	0	63	theme	alginate-f-GO	7:19	arg1	composite					21:29	Sodium alginate-f-GO composite	0:29	Sodium alginate-f-GO composite	0:29	Sodium alginate-f-GO composite hydrogels for tissue regeneration and antitumor applications.					
36374426	3	0	theme	present	772:778	arg1	groups					756:761	flexible glycosyl groups	738:761	flexible glycosyl groups commonly present on proteins produced by mammalian cells	738:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	1	1	from	information	197:207	arg1	PPI					264:266	PPI	264:266	PPI	264:266	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	1	from	information	197:207	arg1	domains					224:230	binding domains	216:230	binding domains	216:230	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	1	from	information	197:207	arg1	interfaces					252:261	protein-protein interfaces	236:261	protein-protein interfaces (PPI)	236:267	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	1	from	information	197:207	arg1	proteins					303:310	these immunologically relevant proteins	272:310	these immunologically relevant proteins	272:310	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	2	2	theme	expression	399:408	arg1	methods					410:416	other expression methods	393:416	other expression methods	393:416	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	4	3	theme	structure	1140:1148	arg1	databases					1150:1158	freely accessible sequence and structure databases	1109:1158	freely accessible sequence and structure databases	1109:1158	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	0	4	theme	Proteins	84:91	arg1	Chromatography					42:55	Size Exclusion Chromatography	27:55	Size Exclusion Chromatography	27:55	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	0	4	theme	Proteins	84:91	arg1	Deglycosylation					7:21	Native Deglycosylation	0:21	Native Deglycosylation	0:21	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	3	5	theme	glycosyl	747:754	arg1	groups					756:761	flexible glycosyl groups	738:761	flexible glycosyl groups commonly present on proteins produced by mammalian cells	738:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	2	6	theme	other	393:397	arg1	methods					410:416	other expression methods	393:416	other expression methods	393:416	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	5	7	theme	suitable	1378:1385	arg1	protein					1370:1376	protein	1370:1376	protein suitable for structural discovery	1370:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	3	8	theme	variable	920:927	arg1	glycans					940:946	these variable, flexible, glycans	914:946	these variable, flexible, glycans	914:946	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	3	9	attach	present	772:778	arg1	proteins					783:790	proteins	783:790	proteins produced by mammalian cells	783:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	3	9	attach	present	772:778	arg2	groups					756:761	flexible glycosyl groups	738:761	flexible glycosyl groups commonly present on proteins produced by mammalian cells	738:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	5	10	theme	simple	1217:1222	arg1	protocol					1253:1260	a simple deglycosylation optimization protocol	1215:1260	a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1215:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	4	11	theme	Myxoma	959:964	arg1	M-T7					980:983	the Myxoma viral protein M-T7	955:983	the Myxoma viral protein M-T7	955:983	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	11	theme	Myxoma	959:964	arg1	case					995:998	a test case	988:998	a test case	988:998	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	6	12	theme	blotting	1568:1575	arg1	techniques					1577:1586	grid blotting techniques	1563:1586	grid blotting techniques for negative stain experiments to validate protein quality	1563:1645	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	12	theme	blotting	1568:1575	arg1	concentration					1444:1456	protein concentration	1436:1456	protein concentration	1436:1456	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	12	theme	blotting	1568:1575	arg1	volumes					1462:1468	volumes	1462:1468	volumes	1462:1468	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	12	theme	blotting	1568:1575	arg1	Considerations					1413:1426	Considerations	1413:1426	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy	1413:1536	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	13	theme	stain	1601:1605	arg1	experiments					1607:1617	negative stain experiments	1592:1617	negative stain experiments	1592:1617	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	3	14	theme	structure	896:904	arg1	observation					858:868	observation	858:868	observation of the conserved tertiary structure beneath these variable, flexible, glycans	858:946	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	0	15	theme	Structural	97:106	arg1	Discovery					108:116	Structural Discovery	97:116	Structural Discovery	97:116	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	2	16	theme	monodispersed	628:640	arg1	sample					642:647	a highly monodispersed sample	619:647	these demand a highly monodispersed sample composed of protein with ordered structure	606:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	17	theme	Protein	313:319	arg1	expression					321:330	Protein expression	313:330	Protein expression in mammalian cells	313:349	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	4	18	theme	approaching	1070:1080	arg1	discovery					1093:1101	approaching structural discovery	1070:1101	approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments	1070:1200	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	1	19	theme	relevant	294:301	arg1	proteins					303:310	these immunologically relevant proteins	272:310	these immunologically relevant proteins	272:310	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	3	20	theme	tertiary	887:894	arg1	structure					896:904	the conserved tertiary structure	873:904	the conserved tertiary structure beneath these variable, flexible, glycans	873:946	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	3	21	with	incompatible	720:731	arg1	groups					756:761	flexible glycosyl groups	738:761	flexible glycosyl groups commonly present on proteins produced by mammalian cells	738:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	1	22	theme	valuable	188:195	arg1	information					197:207	valuable information	188:207	valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins	188:310	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	2	23	theme	ordered	674:680	arg1	structure					682:690	ordered structure	674:690	ordered structure	674:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	24	theme	high-quality	360:371	arg1	protein					373:379	high-quality protein	360:379	high-quality protein	360:379	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	6	25	theme	grid	1563:1566	arg1	techniques					1577:1586	grid blotting techniques	1563:1586	grid blotting techniques for negative stain experiments to validate protein quality	1563:1645	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	25	theme	grid	1563:1566	arg1	concentration					1444:1456	protein concentration	1436:1456	protein concentration	1436:1456	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	25	theme	grid	1563:1566	arg1	volumes					1462:1468	volumes	1462:1468	volumes	1462:1468	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	6	25	theme	grid	1563:1566	arg1	Considerations					1413:1426	Considerations	1413:1426	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy	1413:1536	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	4	26	theme	accessible	1116:1125	arg1	databases					1150:1158	freely accessible sequence and structure databases	1109:1158	freely accessible sequence and structure databases	1109:1158	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	2	27	theme	x-ray	522:526	arg1	crystallography					528:542	x-ray crystallography	522:542	x-ray crystallography	522:542	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	5	28	theme	exclusion	1296:1304	arg1	SEC					1322:1324	SEC	1322:1324	SEC	1322:1324	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	5	28	theme	exclusion	1296:1304	arg1	chromatography					1306:1319	size exclusion chromatography	1291:1319	size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1291:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	2	29	dep	demand	612:617	arg1	sample					642:647	a highly monodispersed sample	619:647	these demand a highly monodispersed sample composed of protein with ordered structure	606:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	6	30	theme	protein	1436:1442	arg1	concentration					1444:1456	protein concentration	1436:1456	protein concentration	1436:1456	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	0	31	theme	Native	0:5	arg1	Deglycosylation					7:21	Native Deglycosylation	0:21	Native Deglycosylation	0:21	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	1	32	theme	proteins	303:310	arg1	PPI					264:266	PPI	264:266	PPI	264:266	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	32	theme	proteins	303:310	arg1	domains					224:230	binding domains	216:230	binding domains	216:230	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	32	theme	proteins	303:310	arg1	interfaces					252:261	protein-protein interfaces	236:261	protein-protein interfaces (PPI)	236:267	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	32	theme	proteins	303:310	arg1	proteins					303:310	these immunologically relevant proteins	272:310	these immunologically relevant proteins	272:310	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	3	33	dep	variable	920:927	arg1	flexible					930:937	flexible	930:937	flexible	930:937	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	0	34	theme	Size	27:30	arg1	Chromatography					42:55	Size Exclusion Chromatography	27:55	Size Exclusion Chromatography	27:55	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	5	35	theme	size	1291:1294	arg1	SEC					1322:1324	SEC	1322:1324	SEC	1322:1324	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	5	35	theme	size	1291:1294	arg1	chromatography					1306:1319	size exclusion chromatography	1291:1319	size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1291:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	4	36	theme	test	990:993	arg1	M-T7					980:983	the Myxoma viral protein M-T7	955:983	the Myxoma viral protein M-T7	955:983	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	36	theme	test	990:993	arg1	case					995:998	a test case	988:998	a test case	988:998	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	2	37	theme	mammalian	335:343	arg1	cells					345:349	mammalian cells	335:349	mammalian cells	335:349	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	38	with	protein	661:667	arg1	structure					682:690	ordered structure	674:690	ordered structure	674:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	1	39	theme	binding	216:222	arg1	domains					224:230	binding domains	216:230	binding domains	216:230	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	39	theme	binding	216:222	arg1	proteins					303:310	these immunologically relevant proteins	272:310	these immunologically relevant proteins	272:310	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	2	40	theme	cryo-EM-based	473:485	arg1	SPA					513:515	SPA	513:515	SPA	513:515	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	40	theme	cryo-EM-based	473:485	arg1	analysis					503:510	cryo-EM-based single particle analysis	473:510	cryo-EM-based single particle analysis (SPA)	473:516	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	3	41	theme	mammalian	804:812	arg1	cells					814:818	mammalian cells	804:818	mammalian cells	804:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	2	42	theme	particle	494:501	arg1	SPA					513:515	SPA	513:515	SPA	513:515	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	42	theme	particle	494:501	arg1	analysis					503:510	cryo-EM-based single particle analysis	473:510	cryo-EM-based single particle analysis (SPA)	473:516	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	1	43	theme	Structural	119:128	arg1	discovery					130:138	Structural discovery	119:138	Structural discovery of viral chemokine binding proteins	119:174	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	6	44	theme	negative	1503:1510	arg1	microscopy					1527:1536	negative stain electron microscopy	1503:1536	negative stain electron microscopy	1503:1536	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	4	45	theme	bioinformatic	1043:1055	arg1	analysis					1057:1064	preliminary bioinformatic analysis	1031:1064	preliminary bioinformatic analysis	1031:1064	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	46	theme	structural	1082:1091	arg1	discovery					1093:1101	approaching structural discovery	1070:1101	approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments	1070:1200	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	5	47	theme	deglycosylation	1224:1238	arg1	protocol					1253:1260	a simple deglycosylation optimization protocol	1215:1260	a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1215:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	2	48	theme	individual	585:594	arg1	proteins					596:603	many individual proteins	580:603	many individual proteins	580:603	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	48	theme	individual	585:594	arg1	demand					612:617	these demand	606:617	these demand a highly monodispersed sample composed of protein with ordered structure	606:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	6	49	theme	negative	1592:1599	arg1	experiments					1607:1617	negative stain experiments	1592:1617	negative stain experiments	1592:1617	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	0	50	theme	Exclusion	32:40	arg1	Chromatography					42:55	Size Exclusion Chromatography	27:55	Size Exclusion Chromatography	27:55	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	2	51	theme	many	580:583	arg1	proteins					596:603	many individual proteins	580:603	many individual proteins	580:603	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	51	theme	many	580:583	arg1	demand					612:617	these demand	606:617	these demand a highly monodispersed sample composed of protein with ordered structure	606:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	0	52	gly	Deglycosylation	7:21	arg1	Proteins					84:91	Viral Chemokine Binding Proteins	60:91	Viral Chemokine Binding Proteins	60:91	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	1	53	theme	protein-protein	236:250	arg1	PPI					264:266	PPI	264:266	PPI	264:266	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	53	theme	protein-protein	236:250	arg1	interfaces					252:261	protein-protein interfaces	236:261	protein-protein interfaces (PPI)	236:267	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	0	54	theme	Viral	60:64	arg1	Proteins					84:91	Viral Chemokine Binding Proteins	60:91	Viral Chemokine Binding Proteins	60:91	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	4	55	theme	sequence	1127:1134	arg1	databases					1150:1158	freely accessible sequence and structure databases	1109:1158	freely accessible sequence and structure databases	1109:1158	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	56	theme	protein	972:978	arg1	M-T7					980:983	the Myxoma viral protein M-T7	955:983	the Myxoma viral protein M-T7	955:983	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	56	theme	protein	972:978	arg1	case					995:998	a test case	988:998	a test case	988:998	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	57	theme	preliminary	1031:1041	arg1	analysis					1057:1064	preliminary bioinformatic analysis	1031:1064	preliminary bioinformatic analysis	1031:1064	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	6	58	theme	stain	1512:1516	arg1	microscopy					1527:1536	negative stain electron microscopy	1503:1536	negative stain electron microscopy	1503:1536	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	5	59	theme	optimization	1240:1251	arg1	protocol					1253:1260	a simple deglycosylation optimization protocol	1215:1260	a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1215:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	2	60	theme	single	487:492	arg1	SPA					513:515	SPA	513:515	SPA	513:515	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	60	theme	single	487:492	arg1	analysis					503:510	cryo-EM-based single particle analysis	473:510	cryo-EM-based single particle analysis (SPA)	473:516	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	61	theme	structural	436:445	arg1	methods					457:463	structural discovery methods	436:463	structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography	436:542	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	61	theme	structural	436:445	arg1	analysis					503:510	cryo-EM-based single particle analysis	473:510	cryo-EM-based single particle analysis (SPA)	473:516	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	61	theme	structural	436:445	arg1	crystallography					528:542	x-ray crystallography	522:542	x-ray crystallography	522:542	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	4	62	theme	viral	966:970	arg1	M-T7					980:983	the Myxoma viral protein M-T7	955:983	the Myxoma viral protein M-T7	955:983	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	4	62	theme	viral	966:970	arg1	case					995:998	a test case	988:998	a test case	988:998	Using the Myxoma viral protein M-T7 as a test case, we discuss considerations and preliminary bioinformatic analysis for approaching structural discovery using freely accessible sequence and structure databases to maximize success and guide experiments.					
36374426	5	63	theme	structural	1391:1400	arg1	discovery					1402:1410	structural discovery	1391:1410	structural discovery	1391:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	3	64	theme	flexible	738:745	arg1	groups					756:761	flexible glycosyl groups	738:761	flexible glycosyl groups commonly present on proteins produced by mammalian cells	738:818	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	1	65	theme	viral	143:147	arg1	proteins					167:174	viral chemokine binding proteins	143:174	viral chemokine binding proteins	143:174	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	3	66	theme	conserved	877:885	arg1	structure					896:904	the conserved tertiary structure	873:904	the conserved tertiary structure beneath these variable, flexible, glycans	873:946	These techniques are often incompatible with flexible glycosyl groups commonly present on proteins produced by mammalian cells and require deglycosylation to enable observation of the conserved tertiary structure beneath these variable, flexible, glycans.					
36374426	1	67	theme	chemokine	149:157	arg1	proteins					167:174	viral chemokine binding proteins	143:174	viral chemokine binding proteins	143:174	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	2	68	from	expression	321:330	arg1	cells					345:349	mammalian cells	335:349	mammalian cells	335:349	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	69	dep	produces	351:358	arg1	use					544:546	use	544:546	use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure	544:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	0	70	theme	Binding	76:82	arg1	Proteins					84:91	Viral Chemokine Binding Proteins	60:91	Viral Chemokine Binding Proteins	60:91	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	2	71	theme	discovery	447:455	arg1	methods					457:463	structural discovery methods	436:463	structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography	436:542	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	71	theme	discovery	447:455	arg1	analysis					503:510	cryo-EM-based single particle analysis	473:510	cryo-EM-based single particle analysis (SPA)	473:516	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	2	71	theme	discovery	447:455	arg1	crystallography					528:542	x-ray crystallography	522:542	x-ray crystallography	522:542	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36374426	6	72	theme	electron	1518:1525	arg1	microscopy					1527:1536	negative stain electron microscopy	1503:1536	negative stain electron microscopy	1503:1536	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	1	73	theme	binding	159:165	arg1	proteins					167:174	viral chemokine binding proteins	143:174	viral chemokine binding proteins	143:174	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	6	74	theme	protein	1631:1637	arg1	quality					1639:1645	protein quality	1631:1645	protein quality	1631:1645	Considerations such as protein concentration and volumes required for crystallography and negative stain electron microscopy are discussed as well as grid blotting techniques for negative stain experiments to validate protein quality.					
36374426	0	75	theme	Chemokine	66:74	arg1	Proteins					84:91	Viral Chemokine Binding Proteins	60:91	Viral Chemokine Binding Proteins	60:91	Native Deglycosylation and Size Exclusion Chromatography of Viral Chemokine Binding Proteins for Structural Discovery.					
36374426	5	76	theme	Endo	1272:1275	arg1	H					1277:1277	Endo H	1272:1277	Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery	1272:1410	We describe a simple deglycosylation optimization protocol utilizing Endo H followed by size exclusion chromatography (SEC) based purification to produce and validate protein suitable for structural discovery.					
36374426	1	77	dep	domains	224:230	arg1	the					212:214	the	212:214	the	212:214	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	1	78	theme	proteins	167:174	arg1	discovery					130:138	Structural discovery	119:138	Structural discovery of viral chemokine binding proteins	119:174	Structural discovery of viral chemokine binding proteins can provide valuable information on the binding domains and protein-protein interfaces (PPI) of these immunologically relevant proteins.					
36374426	2	79	from	proteins	596:603	arg1	data					570:573	data	570:573	data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure	570:690	Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine data from many individual proteins, these demand a highly monodispersed sample composed of protein with ordered structure.					
36012548	1	0	with	films	180:184	arg1	biocompatibility					214:229	biocompatibility	214:229	biocompatibility	214:229	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	1	0	with	films	180:184	arg1	sustainability					236:249	sustainability	236:249	sustainability	236:249	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	1	0	with	films	180:184	arg1	biodegradability					196:211	good biodegradability	191:211	good biodegradability	191:211	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	2	1	theme	tannic	378:383	arg1	COTA					391:394	COTA	391:394	COTA	391:394	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	1	theme	tannic	378:383	arg1	acid					385:388	chitosan/oxidized tannic acid	360:388	chitosan/oxidized tannic acid (COTA)	360:395	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	0	2	theme	Composite	91:99	arg1	Film					101:104	Tannic Acid Composite Film	79:104	Tannic Acid Composite Film	79:104	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	2	3	with	films	407:411	arg1	properties					457:466	excellent mechanical and antibacterial properties	418:466	excellent mechanical and antibacterial properties	418:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	4	theme	chitosan/oxidized	360:376	arg1	COTA					391:394	COTA	391:394	COTA	391:394	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	4	theme	chitosan/oxidized	360:376	arg1	acid					385:388	chitosan/oxidized tannic acid	360:388	chitosan/oxidized tannic acid (COTA)	360:395	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	4	5	theme	phenolic	767:774	arg1	groups					785:790	the phenolic hydroxyl groups	763:790	the phenolic hydroxyl groups	763:790	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	0	6	theme	Schiff	111:116	arg1	Base					118:121	Schiff Base	111:121	Schiff Base	111:121	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	7	7	theme	significant	1197:1207	arg1	effects					1223:1229	significant antibacterial effects	1197:1229	significant antibacterial effects against Escherichia coli (E. coli)	1197:1264	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	7	8	theme	antibacterial	1209:1221	arg1	effects					1223:1229	significant antibacterial effects	1197:1229	significant antibacterial effects against Escherichia coli (E. coli)	1197:1264	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	3	9	theme	tannic	545:550	arg1	TA					558:559	TA	558:559	TA	558:559	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	9	theme	tannic	545:550	arg1	acid					552:555	20% tannic acid	541:555	20% tannic acid (TA)	541:560	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	1	10	theme	food	292:295	arg1	packaging					297:305	food packaging	292:305	food packaging	292:305	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	5	11	theme	chemical	960:967	arg1	bond					969:972	a chemical bond	958:972	a chemical bond	958:972	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	4	12	theme	hydroxyl	776:783	arg1	groups					785:790	the phenolic hydroxyl groups	763:790	the phenolic hydroxyl groups	763:790	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	1	13	theme	packaging	297:305	arg1	field					283:287	the field	279:287	the field of food packaging	279:305	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	3	14	theme	pure	674:677	arg1	CS					689:690	CS	689:690	CS	689:690	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	14	theme	pure	674:677	arg1	chitosan					679:686	the pure chitosan	670:686	the pure chitosan (CS) film	670:696	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	5	15	dep	OTA	894:896	arg1	the					890:892	the	890:892	the	890:892	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	3	16	theme	20	541:542	arg1	%					543:543	%	543:543	%	543:543	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	1	17	theme	good	191:194	arg1	biodegradability					196:211	good biodegradability	191:211	good biodegradability	191:211	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	0	18	theme	Mechanical	41:50	arg1	Strength					52:59	High Mechanical Strength	36:59	High Mechanical Strength	36:59	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	3	19	theme	%	543:543	arg1	TA					558:559	TA	558:559	TA	558:559	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	19	theme	%	543:543	arg1	acid					552:555	20% tannic acid	541:555	20% tannic acid (TA)	541:560	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	5	20	theme	Schiff	861:866	arg1	reaction					873:880	a Schiff base reaction	859:880	a Schiff base reaction between the OTA and CS	859:903	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	2	21	theme	composite	397:405	arg1	films					407:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films	323:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties	323:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	5	22	theme	hydrogen	978:985	arg1	bond					987:990	hydrogen bond	978:990	hydrogen bond	978:990	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	6	23	dep	increased	1110:1118	arg1	compared					1129:1136	compared	1129:1136	compared to that of pure CS film	1129:1160	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	2	24	theme	acid	345:348	arg1	films					407:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films	323:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties	323:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	7	25	theme	food	1293:1296	arg1	applications					1308:1319	food packaging applications	1293:1319	food packaging applications	1293:1319	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	7	26	dep	coli	1251:1254	arg1	coli					1260:1263	E. coli	1257:1263	E. coli	1257:1263	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	7	27	theme	packaging	1298:1306	arg1	applications					1308:1319	food packaging applications	1293:1319	food packaging applications	1293:1319	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	5	28	theme	mechanical	1036:1045	arg1	properties					1047:1056	the mechanical properties	1032:1056	the mechanical properties	1032:1056	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	2	29	theme	chitosan/tannic	329:343	arg1	CTA					351:353	CTA	351:353	CTA	351:353	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	29	theme	chitosan/tannic	329:343	arg1	acid					345:348	novel chitosan/tannic acid	323:348	novel chitosan/tannic acid (CTA)	323:354	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	5	30	dep	OTA	854:856	arg1	the					838:840	the	838:840	the	838:840	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	5	30	dep	OTA	854:856	arg1	addition					842:849	addition	842:849	addition	842:849	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	7	31	theme	CTA	1182:1184	arg1	films					1186:1190	these CTA films	1176:1190	these CTA films with significant antibacterial effects against Escherichia coli (E. coli)	1176:1264	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	0	32	theme	Bond	136:139	arg1	Crosslinking					141:152	Hydrogen Bond Crosslinking	127:152	Hydrogen Bond Crosslinking	127:152	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	2	33	theme	novel	323:327	arg1	CTA					351:353	CTA	351:353	CTA	351:353	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	33	theme	novel	323:327	arg1	acid					345:348	novel chitosan/tannic acid	323:348	novel chitosan/tannic acid (CTA)	323:354	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	34	theme	antibacterial	443:455	arg1	properties					457:466	excellent mechanical and antibacterial properties	418:466	excellent mechanical and antibacterial properties	418:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	3	35	theme	chitosan	679:686	arg1	film					693:696	the pure chitosan (CS) film	670:696	the pure chitosan (CS) film	670:696	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	0	36	theme	Hydrogen	127:134	arg1	Crosslinking					141:152	Hydrogen Bond Crosslinking	127:152	Hydrogen Bond Crosslinking	127:152	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	7	37	with	films	1186:1190	arg1	effects					1223:1229	significant antibacterial effects	1197:1229	significant antibacterial effects against Escherichia coli (E. coli)	1197:1264	Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.					
36012548	2	38	theme	mechanical	428:437	arg1	properties					457:466	excellent mechanical and antibacterial properties	418:466	excellent mechanical and antibacterial properties	418:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	2	39	theme	casting	495:501	arg1	method					503:508	a tape casting method	488:508	a tape casting method	488:508	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	3	40	theme	80.7	624:627	arg1	strength					585:592	the tensile strength	573:592	the tensile strength of the CTA composite film	573:618	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	40	theme	80.7	624:627	arg1	MPa					629:631	MPa	629:631	MPa	629:631	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	6	41	theme	film	1101:1104	arg1	strength					1071:1078	The tensile strength	1059:1078	The tensile strength of 3% COTA composite film	1059:1104	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	2	42	theme	excellent	418:426	arg1	properties					457:466	excellent mechanical and antibacterial properties	418:466	excellent mechanical and antibacterial properties	418:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	0	43	theme	High	36:39	arg1	Strength					52:59	High Mechanical Strength	36:59	High Mechanical Strength	36:59	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	2	44	theme	tape	490:493	arg1	method					503:508	a tape casting method	488:508	a tape casting method	488:508	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
36012548	3	45	theme	composite	605:613	arg1	film					615:618	the CTA composite film	597:618	the CTA composite film	597:618	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	46	theme	tensile	577:583	arg1	MPa					629:631	MPa	629:631	MPa	629:631	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	46	theme	tensile	577:583	arg1	strength					585:592	the tensile strength	573:592	the tensile strength of the CTA composite film	573:618	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	47	theme	film	615:618	arg1	MPa					629:631	MPa	629:631	MPa	629:631	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	3	47	theme	film	615:618	arg1	strength					585:592	the tensile strength	573:592	the tensile strength of the CTA composite film	573:618	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	6	48	theme	COTA	1086:1089	arg1	film					1101:1104	3% COTA composite film	1083:1104	3% COTA composite film	1083:1104	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	0	49	theme	Strength	52:59	arg1	Characterization					16:31	Characterization	16:31	Characterization	16:31	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	0	49	theme	Strength	52:59	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	6	50	theme	CS	1154:1155	arg1	film					1157:1160	pure CS film	1149:1160	pure CS film	1149:1160	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	6	51	theme	%	1084:1084	arg1	film					1101:1104	3% COTA composite film	1083:1104	3% COTA composite film	1083:1104	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	6	52	theme	tensile	1063:1069	arg1	strength					1071:1078	The tensile strength	1059:1078	The tensile strength of 3% COTA composite film	1059:1104	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	6	53	theme	pure	1149:1152	arg1	film					1157:1160	pure CS film	1149:1160	pure CS film	1149:1160	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	6	54	theme	3	1083:1083	arg1	%					1084:1084	%	1084:1084	%	1084:1084	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	6	55	theme	composite	1091:1099	arg1	film					1101:1104	3% COTA composite film	1083:1104	3% COTA composite film	1083:1104	The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film.					
36012548	5	56	theme	base	868:871	arg1	reaction					873:880	a Schiff base reaction	859:880	a Schiff base reaction between the OTA and CS	859:903	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	5	57	theme	dual	921:924	arg1	structure					934:942	a dual network structure	919:942	a dual network structure consisting of a chemical bond and hydrogen bond	919:990	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	3	58	theme	CTA	601:603	arg1	film					615:618	the CTA composite film	597:618	the CTA composite film	597:618	The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film.					
36012548	1	59	theme	composite	170:178	arg1	films					180:184	Chitosan-based composite films	155:184	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability	155:249	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	4	60	theme	o-quinone	812:820	arg1	structure					822:830	an o-quinone structure	809:830	an o-quinone structure	809:830	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	0	61	theme	Acid	86:89	arg1	Film					101:104	Tannic Acid Composite Film	79:104	Tannic Acid Composite Film	79:104	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	5	62	theme	network	926:932	arg1	structure					934:942	a dual network structure	919:942	a dual network structure consisting of a chemical bond and hydrogen bond	919:990	With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties.					
36012548	4	63	theme	tannic	727:732	arg1	OTA					740:742	OTA	740:742	OTA	740:742	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	4	63	theme	tannic	727:732	arg1	acid					734:737	tannic acid	727:737	oxidized tannic acid (OTA)	718:743	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	1	64	theme	Chitosan-based	155:168	arg1	films					180:184	Chitosan-based composite films	155:184	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability	155:249	Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging.					
36012548	0	65	theme	Tannic	79:84	arg1	Acid					86:89	Tannic Acid	79:89	Tannic Acid Composite Film	79:104	Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking.					
36012548	4	66	theme	oxidized	718:725	arg1	OTA					740:742	OTA	740:742	OTA	740:742	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	4	66	theme	oxidized	718:725	arg1	acid					734:737	tannic acid	727:737	oxidized tannic acid (OTA)	718:743	TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure.					
36012548	2	67	theme	acid	385:388	arg1	films					407:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films	323:411	novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties	323:466	In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method.					
37207758	6	0	theme	magnetic	895:902	arg1	field					904:908	a high magnetic field	888:908	a high magnetic field	888:908	The cells exposed to a high magnetic field were more likely to undergo apoptosis than those exposed to a low magnetic field.					
37207758	4	1	contain	had	638:640	arg2	efficacy					649:656	better efficacy	642:656	better efficacy for anti-cancer drug screening	642:687	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	4	1	contain	had	638:640	arg1	model					611:615	The 3D tumor model	598:615	The 3D tumor model based on these beads	598:636	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	4	2	theme	2D	698:699	arg1	model					714:718	the 2D cell culture model	694:718	the 2D cell culture model	694:718	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	0	3	theme	tumor	69:73	arg1	model					75:79	in vitro tumor model	60:79	in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis	60:148	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	4	4	theme	culture	706:712	arg1	model					714:718	the 2D cell culture model	694:718	the 2D cell culture model	694:718	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	7	5	theme	tumor	1086:1090	arg1	models					1092:1097	porous beads-based tumor models	1067:1097	porous beads-based tumor models	1067:1097	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	3	6	theme	tumor-like	556:565	arg1	aggregates					567:576	tumor-like aggregates	556:576	tumor-like aggregates	556:576	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	7	7	theme	porous	1030:1035	arg1	beads					1037:1041	the SA/SF porous beads	1020:1041	the SA/SF porous beads	1020:1041	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	7	7	theme	porous	1030:1035	arg1	useful					1108:1113	useful	1108:1113	useful	1108:1113	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	3	8	theme	A549	492:495	arg1	cells					497:501	A549 cells	492:501	A549 cells	492:501	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	4	9	theme	drug	674:677	arg1	screening					679:687	anti-cancer drug screening	662:687	anti-cancer drug screening	662:687	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	1	10	theme	cell	249:252	arg1	culture					254:260	cell culture	249:260	cell culture	249:260	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	4	11	theme	anti-cancer	662:672	arg1	screening					679:687	anti-cancer drug screening	662:687	anti-cancer drug screening	662:687	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	7	12	theme	mechanobiology	1159:1172	arg1	studies					1174:1180	mechanobiology studies	1159:1180	mechanobiology studies	1159:1180	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	1	13	theme	culture	254:260	arg1	limitations					234:244	the limitations	230:244	the limitations of cell culture and animal models for designing and screening anticancer drugs	230:323	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	14	theme	anti-cancer	98:108	arg1	drug					110:113	anti-cancer drug	98:113	anti-cancer drug	98:113	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	6	15	theme	low	972:974	arg1	field					985:989	a low magnetic field	970:989	a low magnetic field	970:989	The cells exposed to a high magnetic field were more likely to undergo apoptosis than those exposed to a low magnetic field.					
37207758	4	16	theme	cell	701:704	arg1	model					714:718	the 2D cell culture model	694:718	the 2D cell culture model	694:718	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	2	17	theme	tumor	353:357	arg1	models					359:364	in vitro 3D tumor models	341:364	in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	341:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	5	18	theme	iron	788:791	arg1	nanoparticles					799:811	superparamagnetic iron oxide nanoparticles	770:811	superparamagnetic iron oxide nanoparticles	770:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	7	19	theme	porous	1067:1072	arg1	models					1092:1097	porous beads-based tumor models	1067:1097	porous beads-based tumor models	1067:1097	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	2	20	theme	sodium	397:402	arg1	beads					441:445	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	beads	441:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	1	21	theme	3D	170:171	arg1	models					203:208	3D scaffold-based in vitro tumor models	170:208	3D scaffold-based in vitro tumor models	170:208	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	22	theme	porous	3:8	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	2	23	theme	porous	434:439	arg1	beads					441:445	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	beads	441:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	7	24	theme	tissue	1135:1140	arg1	engineering					1142:1152	tissue engineering	1135:1152	tissue engineering	1135:1152	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	3	25	theme	high	509:512	arg1	tendency					514:521	a high tendency	507:521	a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads	507:595	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	1	26	theme	scaffold-based	173:186	arg1	models					203:208	3D scaffold-based in vitro tumor models	170:208	3D scaffold-based in vitro tumor models	170:208	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	27	theme	3D	0:1	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	7	28	theme	beads-based	1074:1084	arg1	models					1092:1097	porous beads-based tumor models	1067:1097	porous beads-based tumor models	1067:1097	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	4	29	theme	better	642:647	arg1	efficacy					649:656	better efficacy	642:656	better efficacy for anti-cancer drug screening	642:687	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	1	30	theme	in	188:189	arg1	models					203:208	3D scaffold-based in vitro tumor models	170:208	3D scaffold-based in vitro tumor models	170:208	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	31	theme	alginate-silk	17:29	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	1	32	theme	animal	266:271	arg1	models					273:278	animal models	266:278	animal models for designing and screening anticancer drugs	266:323	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	7	33	theme	SA/SF	1024:1028	arg1	beads					1037:1041	the SA/SF porous beads	1020:1041	the SA/SF porous beads	1020:1041	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	7	33	theme	SA/SF	1024:1028	arg1	useful					1108:1113	useful	1108:1113	useful	1108:1113	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	6	34	theme	magnetic	976:983	arg1	field					985:989	a low magnetic field	970:989	a low magnetic field	970:989	The cells exposed to a high magnetic field were more likely to undergo apoptosis than those exposed to a low magnetic field.					
37207758	0	35	theme	sodium	10:15	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	1	36	theme	models	273:278	arg1	limitations					234:244	the limitations	230:244	the limitations of cell culture and animal models for designing and screening anticancer drugs	230:323	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	37	theme	drug	110:113	arg1	screening					85:93	screening	85:93	screening of anti-cancer drug and induction of magneto-apoptosis	85:148	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	3	38	theme	SA/SF	585:589	arg1	beads					591:595	SA/SF beads	585:595	SA/SF beads	585:595	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	0	39	dep	in	60:61	arg1	vitro					63:67	vitro	63:67	vitro	63:67	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	1	40	theme	tumor	197:201	arg1	models					203:208	3D scaffold-based in vitro tumor models	170:208	3D scaffold-based in vitro tumor models	170:208	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	41	theme	composite	39:47	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	4	42	theme	tumor	605:609	arg1	model					611:615	The 3D tumor model	598:615	The 3D tumor model based on these beads	598:636	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	2	43	theme	alginate	379:386	arg1	SA					389:390	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	SA	389:390	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	6	44	theme	high	890:893	arg1	field					904:908	a high magnetic field	888:908	a high magnetic field	888:908	The cells exposed to a high magnetic field were more likely to undergo apoptosis than those exposed to a low magnetic field.					
37207758	2	45	theme	3D	350:351	arg1	models					359:364	in vitro 3D tumor models	341:364	in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	341:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	1	46	theme	models	203:208	arg1	development					155:165	The development	151:165	The development of 3D scaffold-based in vitro tumor models	151:208	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	47	theme	fibroin	31:37	arg1	bead					49:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead	0:52	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	0	48	theme	induction	119:127	arg1	screening					85:93	screening	85:93	screening of anti-cancer drug and induction of magneto-apoptosis	85:148	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	1	49	dep	in	188:189	arg1	vitro					191:195	vitro	191:195	vitro	191:195	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	2	50	theme	sodium	372:377	arg1	SA					389:390	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	SA	389:390	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	7	51	theme	drug	1119:1122	arg1	screening					1124:1132	drug screening	1119:1132	drug screening	1119:1132	These findings suggest that the SA/SF porous beads and SPIONs loaded SA/SF porous beads-based tumor models could be useful for drug screening, tissue engineering, and mechanobiology studies.					
37207758	3	52	contain	had	503:505	arg2	tendency					514:521	a high tendency	507:521	a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads	507:595	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	3	52	contain	had	503:505	arg1	cells					497:501	A549 cells	492:501	A549 cells	492:501	The beads were non-toxic and A549 cells had a high tendency to adhere, proliferate, and form tumor-like aggregates within SA/SF beads.					
37207758	5	53	theme	SA/SF	739:743	arg1	beads					752:756	the SA/SF porous beads	735:756	the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles	735:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	5	54	theme	magneto-apoptosis	840:856	arg1	ability					858:864	their magneto-apoptosis ability	834:864	their magneto-apoptosis ability	834:864	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	2	55	theme	fibroin	418:424	arg1	beads					441:445	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	beads	441:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	1	56	theme	screening	298:306	arg1	drugs					319:323	and screening anticancer drugs	294:323	drugs	319:323	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	0	57	theme	magneto-apoptosis	132:148	arg1	induction					119:127	induction	119:127	induction of magneto-apoptosis	119:148	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	0	57	theme	magneto-apoptosis	132:148	arg1	drug					110:113	anti-cancer drug	98:113	anti-cancer drug	98:113	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	5	58	used	used	818:821	arg2	beads					752:756	the SA/SF porous beads	735:756	the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles	735:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	4	59	theme	3D	602:603	arg1	model					611:615	The 3D tumor model	598:615	The 3D tumor model based on these beads	598:636	The 3D tumor model based on these beads had better efficacy for anti-cancer drug screening than the 2D cell culture model.					
37207758	1	60	theme	anticancer	308:317	arg1	drugs					319:323	and screening anticancer drugs	294:323	drugs	319:323	The development of 3D scaffold-based in vitro tumor models can help to address the limitations of cell culture and animal models for designing and screening anticancer drugs.					
37207758	2	61	dep	in	341:342	arg1	vitro					344:348	vitro	344:348	vitro	344:348	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	2	62	theme	SA/SF	427:431	arg1	beads					441:445	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	beads	441:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	2	63	theme	in	341:342	arg1	models					359:364	in vitro 3D tumor models	341:364	in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	341:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
37207758	5	64	theme	superparamagnetic	770:786	arg1	nanoparticles					799:811	superparamagnetic iron oxide nanoparticles	770:811	superparamagnetic iron oxide nanoparticles	770:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	5	65	theme	oxide	793:797	arg1	nanoparticles					799:811	superparamagnetic iron oxide nanoparticles	770:811	superparamagnetic iron oxide nanoparticles	770:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	0	66	theme	in	60:61	arg1	model					75:79	in vitro tumor model	60:79	in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis	60:148	3D porous sodium alginate-silk fibroin composite bead based in vitro tumor model for screening of anti-cancer drug and induction of magneto-apoptosis.					
37207758	5	67	theme	porous	745:750	arg1	beads					752:756	the SA/SF porous beads	735:756	the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles	735:811	Additionally, the SA/SF porous beads loaded with superparamagnetic iron oxide nanoparticles were used to explore their magneto-apoptosis ability.					
37207758	2	68	theme	alginate/silk	404:416	arg1	beads					441:445	sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads	372:445	beads	441:445	In this study, in vitro 3D tumor models using sodium alginate (SA) and sodium alginate/silk fibroin (SA/SF) porous beads were developed.					
35104108	4	0	theme	structural	935:944	arg1	transition					946:955	no structural transition	932:955	no structural transition	932:955	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	1	1	theme	optical	305:311	arg1	microscope					313:322	an optical microscope	302:322	an optical microscope	302:322	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	6	2	theme	water	1219:1223	arg1	content					1225:1231	a water content	1217:1231	a water content higher than 20%	1217:1247	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	1	3	theme	cellulose	151:159	arg1	beads					165:169	regenerated cellulose gel beads	139:169	regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	139:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	7	4	theme	drying	1352:1357	arg1	behavior					1359:1366	the drying behavior	1348:1366	the drying behavior governed by the cellulose concentration and nonsolvent composition	1348:1433	To describe the drying behavior governed by the cellulose concentration and nonsolvent composition, a simplified phase diagram is proposed.					
35104108	1	5	theme	water/ethanol	229:241	arg1	mixtures					243:250	water/ethanol mixtures	229:250	water/ethanol mixtures	229:250	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	1	5	theme	water/ethanol	229:241	arg1	water					213:217	water	213:217	water	213:217	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	2	6	theme	structural	464:473	arg1	evolution					475:483	the structural evolution	460:483	the structural evolution of beads during drying	460:506	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	1	7	with	scale	291:295	arg1	microscope					313:322	an optical microscope	302:322	an optical microscope	302:322	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	1	8	theme	gel	161:163	arg1	beads					165:169	regenerated cellulose gel beads	139:169	regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	139:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	0	9	theme	Concentration	85:97	arg1	Effects					74:80	The Effects	70:80	The Effects of Concentration and Nonsolvents	70:113	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	6	10	theme	three-step	1128:1137	arg1	process					1146:1152	A three-step drying process	1126:1152	A three-step drying process	1126:1152	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	4	11	theme	two-step	892:899	arg1	process					908:914	a two-step drying process	890:914	a two-step drying process	890:914	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	3	12	theme	mixture	689:695	arg1	composition					697:707	the water/ethanol mixture composition	671:707	the water/ethanol mixture composition	671:707	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	4	13	theme	cellulose	841:849	arg1	higher					868:873	higher	868:873	higher	868:873	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	4	13	theme	cellulose	841:849	arg1	concentration					851:863	the cellulose concentration	837:863	the cellulose concentration	837:863	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	3	14	theme	crystalline	789:799	arg1	structure					801:809	a cellulose II crystalline structure	774:809	a cellulose II crystalline structure	774:809	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	0	15	theme	Nonsolvents	103:113	arg1	Effects					74:80	The Effects	70:80	The Effects of Concentration and Nonsolvents	70:113	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	6	16	theme	water/ethanol	1189:1201	arg1	mixtures					1203:1210	water/ethanol mixtures	1189:1210	water/ethanol mixtures with a water content higher than 20%	1189:1247	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	1	17	theme	beads	165:169	arg1	behavior					127:134	The drying behavior	116:134	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	116:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	2	18	theme	cellulose	435:443	arg1	concentration					445:457	the cellulose concentration	431:457	the cellulose concentration	431:457	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	3	19	theme	structure	801:809	arg1	formation					761:769	the formation	757:769	the formation of a cellulose II crystalline structure	757:809	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	6	20	theme	drying	1267:1272	arg1	process					1274:1280	a two-step drying process	1256:1280	a two-step drying process	1256:1280	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	3	21	theme	drying	615:620	arg1	process					622:628	the drying process	611:628	the drying process	611:628	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	3	22	theme	water/ethanol	675:687	arg1	composition					697:707	the water/ethanol mixture composition	671:707	the water/ethanol mixture composition	671:707	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	6	23	theme	water	1303:1307	arg1	lower					1320:1324	lower	1320:1324	lower	1320:1324	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	6	23	theme	water	1303:1307	arg1	content					1309:1315	the water content	1299:1315	the water content	1299:1315	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	4	24	theme	drying	901:906	arg1	process					908:914	a two-step drying process	890:914	a two-step drying process	890:914	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	3	25	theme	sharp	712:716	arg1	transition					729:738	a sharp structural transition	710:738	a sharp structural transition corresponding to the formation of a cellulose II crystalline structure	710:809	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	7	26	theme	cellulose	1384:1392	arg1	concentration					1394:1406	the cellulose concentration	1380:1406	the cellulose concentration	1380:1406	To describe the drying behavior governed by the cellulose concentration and nonsolvent composition, a simplified phase diagram is proposed.					
35104108	1	27	theme	different	184:192	arg1	nonsolvents					194:204	different nonsolvents	184:204	different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	184:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	3	28	theme	structural	718:727	arg1	transition					729:738	a sharp structural transition	710:738	a sharp structural transition corresponding to the formation of a cellulose II crystalline structure	710:809	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	2	29	theme	regimes	538:544	arg1	regimes					538:544	three distinct regimes	523:544	three distinct regimes	523:544	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	2	29	theme	regimes	538:544	arg1	one					516:518	one	516:518	one	516:518	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	0	30	theme	Drying	18:23	arg1	Behavior					25:32	the Drying Behavior	14:32	the Drying Behavior of Regenerated Cellulose Gel Beads	14:67	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	5	31	theme	nonsolvent	1102:1111	arg1	composition					1113:1123	the nonsolvent composition	1098:1123	the nonsolvent composition	1098:1123	Third, when the cellulose concentration is between 0.5 and 5.0 wt %, the drying process is dependent on the nonsolvent composition.					
35104108	2	32	theme	distinct	529:536	arg1	regimes					538:544	three distinct regimes	523:544	three distinct regimes	523:544	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	7	33	theme	simplified	1438:1447	arg1	diagram					1455:1461	a simplified phase diagram	1436:1461	a simplified phase diagram	1436:1461	To describe the drying behavior governed by the cellulose concentration and nonsolvent composition, a simplified phase diagram is proposed.					
35104108	0	34	theme	Regenerated	37:47	arg1	Beads					63:67	Regenerated Cellulose Gel Beads	37:67	Regenerated Cellulose Gel Beads	37:67	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	1	35	theme	small-angle/wide-angle	354:375	arg1	SAXS/WAXS					395:403	SAXS/WAXS	395:403	SAXS/WAXS	395:403	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	1	35	theme	small-angle/wide-angle	354:375	arg1	scattering					383:392	small-angle/wide-angle X-ray scattering	354:392	small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques	354:415	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	5	36	theme	drying	1067:1072	arg1	dependent					1085:1093	dependent	1085:1093	dependent	1085:1093	Third, when the cellulose concentration is between 0.5 and 5.0 wt %, the drying process is dependent on the nonsolvent composition.					
35104108	5	36	theme	drying	1067:1072	arg1	process					1074:1080	the drying process	1063:1080	the drying process	1063:1080	Third, when the cellulose concentration is between 0.5 and 5.0 wt %, the drying process is dependent on the nonsolvent composition.					
35104108	1	37	dep	water	213:217	arg1	e.g.					207:210	e.g.	207:210	e.g.	207:210	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	6	38	theme	two-step	1258:1265	arg1	process					1274:1280	a two-step drying process	1256:1280	a two-step drying process	1256:1280	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	0	39	theme	Gel	59:61	arg1	Beads					63:67	Regenerated Cellulose Gel Beads	37:67	Regenerated Cellulose Gel Beads	37:67	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	1	40	theme	macroscopic	279:289	arg1	scale					291:295	the macroscopic scale	275:295	the macroscopic scale with an optical microscope	275:322	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	1	41	theme	scattering	383:392	arg1	techniques					406:415	small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques	354:415	small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques	354:415	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	0	42	theme	Cellulose	49:57	arg1	Beads					63:67	Regenerated Cellulose Gel Beads	37:67	Regenerated Cellulose Gel Beads	37:67	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	7	43	theme	nonsolvent	1412:1421	arg1	composition					1423:1433	nonsolvent composition	1412:1433	nonsolvent composition	1412:1433	To describe the drying behavior governed by the cellulose concentration and nonsolvent composition, a simplified phase diagram is proposed.					
35104108	3	44	theme	cellulose	563:571	arg1	concentration					573:585	the cellulose concentration	559:585	the cellulose concentration	559:585	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	3	44	theme	cellulose	563:571	arg1	lower					590:594	lower	590:594	lower	590:594	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	1	45	theme	X-ray	377:381	arg1	SAXS/WAXS					395:403	SAXS/WAXS	395:403	SAXS/WAXS	395:403	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	1	45	theme	X-ray	377:381	arg1	scattering					383:392	small-angle/wide-angle X-ray scattering	354:392	small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques	354:415	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	7	46	theme	phase	1449:1453	arg1	diagram					1455:1461	a simplified phase diagram	1436:1461	a simplified phase diagram	1436:1461	To describe the drying behavior governed by the cellulose concentration and nonsolvent composition, a simplified phase diagram is proposed.					
35104108	6	47	theme	higher	1233:1238	arg1	content					1225:1231	a water content	1217:1231	a water content higher than 20%	1217:1247	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	6	48	theme	drying	1139:1144	arg1	process					1146:1152	A three-step drying process	1126:1152	A three-step drying process	1126:1152	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	1	49	theme	drying	120:125	arg1	behavior					127:134	The drying behavior	116:134	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	116:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
35104108	6	50	with	mixtures	1203:1210	arg1	content					1225:1231	a water content	1217:1231	a water content higher than 20%	1217:1247	A three-step drying process takes place for beads swollen with water/ethanol mixtures with a water content higher than 20%, while a two-step drying process is observed when the water content is lower than 20%.					
35104108	3	51	theme	wt	605:606	arg1	%					608:608	0.5 wt %	601:608	0.5 wt %	601:608	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	5	52	theme	cellulose	1010:1018	arg1	concentration					1020:1032	the cellulose concentration	1006:1032	the cellulose concentration	1006:1032	Third, when the cellulose concentration is between 0.5 and 5.0 wt %, the drying process is dependent on the nonsolvent composition.					
35104108	4	53	theme	wt	884:885	arg1	%					887:887	5.0 wt %	880:887	5.0 wt %	880:887	Second, when the cellulose concentration is higher than 5.0 wt %, a two-step drying process is observed and no structural transition occurs for any of the beads studied.					
35104108	3	54	theme	cellulose	776:784	arg1	structure					801:809	a cellulose II crystalline structure	774:809	a cellulose II crystalline structure	774:809	First, when the cellulose concentration is lower than 0.5 wt %, the drying process comprises three steps and, regardless of the water/ethanol mixture composition, a sharp structural transition corresponding to the formation of a cellulose II crystalline structure is observed.					
35104108	2	55	theme	beads	488:492	arg1	evolution					475:483	the structural evolution	460:483	the structural evolution of beads during drying	460:506	Depending on the cellulose concentration, the structural evolution of beads during drying follows one of three distinct regimes.					
35104108	0	56	theme	Beads	63:67	arg1	Behavior					25:32	the Drying Behavior	14:32	the Drying Behavior of Regenerated Cellulose Gel Beads	14:67	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	5	57	theme	wt	1057:1058	arg1	%					1060:1060	0.5 and 5.0 wt %	1045:1060	0.5 and 5.0 wt %	1045:1060	Third, when the cellulose concentration is between 0.5 and 5.0 wt %, the drying process is dependent on the nonsolvent composition.					
35104108	0	58	dep	Understanding	0:12	arg1	Effects					74:80	The Effects	70:80	The Effects of Concentration and Nonsolvents	70:113	Understanding the Drying Behavior of Regenerated Cellulose Gel Beads: The Effects of Concentration and Nonsolvents.					
35104108	1	59	theme	regenerated	139:149	arg1	beads					165:169	regenerated cellulose gel beads	139:169	regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures)	139:251	The drying behavior of regenerated cellulose gel beads swollen with different nonsolvents (e.g., water, ethanol, water/ethanol mixtures) is studied in situ on the macroscopic scale with an optical microscope as well as on nanoscale using small-angle/wide-angle X-ray scattering (SAXS/WAXS) techniques.					
36913407	3	0	theme	micellar	722:729	arg1	structures					731:740	large giant micellar structures	710:740	large giant micellar structures	710:740	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	2	1	theme	DMPC-d27	395:402	arg1	bilayers					404:411	deuterated DMPC-d27 bilayers	384:411	deuterated DMPC-d27 bilayers	384:411	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	6	2	theme	NMR	1429:1431	arg1	spectra					1433:1439	NMR spectra	1429:1439	NMR spectra	1429:1439	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	5	3	theme	TrimβMLC	1213:1220	arg1	micelles					1222:1229	pure TrimβMLC micelles	1208:1229	pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative	1208:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	4	4	theme	micellar	917:924	arg1	aggregates					926:935	small and large micellar aggregates	901:935	small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes	901:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	5	5	from	°C	1177:1178	arg1	extinction					1160:1169	complete extinction	1151:1169	complete extinction at 13 °C	1151:1178	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	1	6	theme	membrane	194:201	arg1	mimetics					203:210	useful isotropic or anisotropic membrane mimetics	162:210	useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes	162:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	3	7	theme	20	620:621	arg1	%					622:622	%	622:622	%	622:622	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	2	8	theme	amphiphilic	322:332	arg1	derivative					334:343	a wedge-shaped amphiphilic derivative	307:343	a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC)	307:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	8	theme	amphiphilic	322:332	arg1	able					455:458	able	455:458	able	455:458	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	9	9	theme	similar	1945:1951	arg1	spectra					1967:1973	similar deuterium NMR spectra	1945:1973	similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before	1945:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	1	10	theme	biological	238:247	arg1	membranes					249:257	biological membranes	238:257	biological membranes	238:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	7	11	theme	unsaturated	1605:1615	arg1	membranes					1622:1630	unsaturated POPC membranes	1605:1630	unsaturated POPC membranes	1605:1630	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	9	12	theme	NMR	1963:1965	arg1	spectra					1967:1973	similar deuterium NMR spectra	1945:1973	similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before	1945:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	3	13	theme	cyclodextrin	624:635	arg1	derivative					637:646	20% cyclodextrin derivative	620:646	20% cyclodextrin derivative	620:646	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	4	14	theme	broad	768:772	arg1	component					801:809	a broad composite 2H NMR isotropic component	766:809	a broad composite 2H NMR isotropic component	766:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	5	15	theme	=	1088:1088	arg1	°C					1095:1096	Tc = 21.5 °C	1085:1096	Tc = 21.5 °C	1085:1096	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	15	theme	=	1088:1088	arg1	membranes					1074:1082	pure DMPC-d27 membranes	1060:1082	pure DMPC-d27 membranes (Tc = 21.5 °C)	1060:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	3	16	theme	present	589:595	arg1	paper					597:601	the present paper	585:601	the present paper	585:601	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	9	17	theme	composite	1996:2004	arg1	components					2016:2025	identical composite isotropic components	1986:2025	identical composite isotropic components which were never characterized before	1986:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	8	18	theme	DMPC	1785:1788	arg1	aggregates					1799:1808	possible DMPC bicellar aggregates	1776:1808	possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC)	1776:1893	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	8	18	theme	DMPC	1785:1788	arg1	those					1818:1822	those	1818:1822	those	1818:1822	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	1	19	theme	useful	162:167	arg1	mimetics					203:210	useful isotropic or anisotropic membrane mimetics	162:210	useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes	162:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	2	20	theme	membranes	530:538	arg1	fragmentation					495:507	fragmentation	495:507	fragmentation	495:507	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	20	theme	membranes	530:538	arg1	orientation					479:489	magnetic orientation	470:489	magnetic orientation	470:489	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	0	21	theme	Bicellar-like	80:92	arg1	Aggregates					94:103	Bicellar-like Aggregates	80:103	Bicellar-like Aggregates	80:103	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.					
36913407	8	22	theme	aggregates	1799:1808	arg1	formation					1763:1771	the formation	1759:1771	the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC)	1759:1893	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	7	23	theme	No	1545:1546	arg1	orientation					1557:1567	No membrane orientation	1545:1567	No membrane orientation	1545:1567	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	5	24	theme	micellar	1104:1111	arg1	aggregates					1113:1122	the micellar aggregates	1100:1122	the micellar aggregates	1100:1122	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	4	25	theme	2H	784:785	arg1	component					801:809	a broad composite 2H NMR isotropic component	766:809	a broad composite 2H NMR isotropic component	766:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	2	26	theme	acyl	430:433	arg1	chain					435:439	a lauryl acyl chain	421:439	a lauryl acyl chain (TrimβMLC)	421:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	26	theme	acyl	430:433	arg1	TrimβMLC					442:449	TrimβMLC	442:449	TrimβMLC	442:449	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	6	27	theme	TrimβMLC	1414:1421	arg1	TrimβMLC					1414:1421	TrimβMLC	1414:1421	TrimβMLC	1414:1421	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	6	27	theme	TrimβMLC	1414:1421	arg1	%					1402:1402	10%	1400:1402	10%	1400:1402	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	6	27	theme	TrimβMLC	1414:1421	arg1	%					1409:1409	5%	1408:1409	5%	1408:1409	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	1	28	theme	Small	106:110	arg1	aggregates					126:135	Small bilayer lipid aggregates	106:135	Small bilayer lipid aggregates such as bicelles	106:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	1	28	theme	Small	106:110	arg1	bicelles					145:152	bicelles	145:152	bicelles	145:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	4	29	theme	isotropic	791:799	arg1	component					801:809	a broad composite 2H NMR isotropic component	766:809	a broad composite 2H NMR isotropic component	766:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	0	30	theme	DMPC	17:20	arg1	Membranes					22:30	DMPC Membranes	17:30	DMPC Membranes	17:30	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.					
36913407	1	31	theme	lipid	120:124	arg1	aggregates					126:135	Small bilayer lipid aggregates	106:135	Small bilayer lipid aggregates such as bicelles	106:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	1	31	theme	lipid	120:124	arg1	bicelles					145:152	bicelles	145:152	bicelles	145:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	5	32	theme	derivative	1322:1331	arg1	derivative					1322:1331	the cyclodextrin derivative	1305:1331	the cyclodextrin derivative	1305:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	32	theme	derivative	1322:1331	arg1	amount					1295:1300	only a small amount	1282:1300	only a small amount of the cyclodextrin derivative	1282:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	33	theme	pure	1060:1063	arg1	°C					1095:1096	Tc = 21.5 °C	1085:1096	Tc = 21.5 °C	1085:1096	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	33	theme	pure	1060:1063	arg1	membranes					1074:1082	pure DMPC-d27 membranes	1060:1082	pure DMPC-d27 membranes (Tc = 21.5 °C)	1060:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	2	34	theme	deuterated	384:393	arg1	bilayers					404:411	deuterated DMPC-d27 bilayers	384:411	deuterated DMPC-d27 bilayers	384:411	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	0	35	theme	Wedge-Shaped	37:48	arg1	Cyclodextrin					62:73	a Wedge-Shaped Amphiphilic Cyclodextrin	35:73	a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates	35:103	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.					
36913407	5	36	theme	membranes	1074:1082	arg1	transition					1046:1055	the fluid-to-gel transition	1029:1055	the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C)	1029:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	3	37	theme	giant	716:720	arg1	structures					731:740	large giant micellar structures	710:740	large giant micellar structures	710:740	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	5	38	theme	lipid	1239:1243	arg1	bilayers					1245:1252	lipid bilayers	1239:1252	lipid bilayers	1239:1252	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	6	39	theme	possible	1452:1459	arg1	interactions					1461:1472	possible interactions	1452:1472	possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase	1452:1542	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	6	40	with	interactions	1461:1472	arg1	lipids					1513:1518	fluid-like lipids	1502:1518	fluid-like lipids of the Pβ' ripple phase	1502:1542	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	3	41	theme	fragmentation	545:557	arg1	process					559:565	The fragmentation process	541:565	The fragmentation process fully detailed in the present paper	541:601	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	5	42	theme	pure	1208:1211	arg1	micelles					1222:1229	pure TrimβMLC micelles	1208:1229	pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative	1208:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	4	43	theme	small	901:905	arg1	aggregates					926:935	small and large micellar aggregates	901:935	small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes	901:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	8	44	theme	dihexanoylphosphatidylcholine	1858:1886	arg1	insertion					1845:1853	insertion	1845:1853	insertion of dihexanoylphosphatidylcholine (DHPC)	1845:1893	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	2	45	theme	wedge-shaped	309:320	arg1	derivative					334:343	a wedge-shaped amphiphilic derivative	307:343	a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC)	307:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	45	theme	wedge-shaped	309:320	arg1	able					455:458	able	455:458	able	455:458	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	8	46	theme	possible	1776:1783	arg1	aggregates					1799:1808	possible DMPC bicellar aggregates	1776:1808	possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC)	1776:1893	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	8	46	theme	possible	1776:1783	arg1	those					1818:1822	those	1818:1822	those	1818:1822	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	5	47	theme	micelles	1222:1229	arg1	release					1197:1203	a probable release	1186:1203	a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative	1186:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	4	48	theme	large	911:915	arg1	aggregates					926:935	small and large micellar aggregates	901:935	small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes	901:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	1	49	theme	anisotropic	182:192	arg1	mimetics					203:210	useful isotropic or anisotropic membrane mimetics	162:210	useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes	162:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	2	50	theme	multilamellar	516:528	arg1	membranes					530:538	the multilamellar membranes	512:538	the multilamellar membranes	512:538	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	51	theme	trimethyl	348:356	arg1	βcyclodextrin					358:370	trimethyl βcyclodextrin	348:370	trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC)	348:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	6	52	theme	fluid-like	1502:1511	arg1	lipids					1513:1518	fluid-like lipids	1502:1518	fluid-like lipids of the Pβ' ripple phase	1502:1542	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	1	53	theme	structural	216:225	arg1	studies					227:233	structural studies	216:233	structural studies of biological membranes	216:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	7	54	theme	POPC	1617:1620	arg1	membranes					1622:1630	unsaturated POPC membranes	1605:1630	unsaturated POPC membranes	1605:1630	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	6	55	theme	Bilayer	1334:1340	arg1	fragmentation					1342:1354	Bilayer fragmentation	1334:1354	Bilayer fragmentation between Tc and 13 °C	1334:1375	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	6	56	theme	aggregates	1486:1495	arg1	interactions					1461:1472	possible interactions	1452:1472	possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase	1452:1542	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	9	57	theme	deuterium	1953:1961	arg1	spectra					1967:1973	similar deuterium NMR spectra	1945:1973	similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before	1945:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	3	58	theme	%	622:622	arg1	derivative					637:646	20% cyclodextrin derivative	620:646	20% cyclodextrin derivative	620:646	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	5	59	theme	Tc	1085:1086	arg1	°C					1095:1096	Tc = 21.5 °C	1085:1096	Tc = 21.5 °C	1085:1096	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	59	theme	Tc	1085:1086	arg1	membranes					1074:1082	pure DMPC-d27 membranes	1060:1082	pure DMPC-d27 membranes (Tc = 21.5 °C)	1060:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	2	60	theme	deuterium	288:296	arg1	NMR					298:300	deuterium NMR	288:300	deuterium NMR	288:300	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	9	61	theme	identical	1986:1994	arg1	components					2016:2025	identical composite isotropic components	1986:2025	identical composite isotropic components which were never characterized before	1986:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	5	62	theme	small	1289:1293	arg1	derivative					1322:1331	the cyclodextrin derivative	1305:1331	the cyclodextrin derivative	1305:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	62	theme	small	1289:1293	arg1	amount					1295:1300	only a small amount	1282:1300	only a small amount of the cyclodextrin derivative	1282:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	7	63	theme	membrane	1548:1555	arg1	orientation					1557:1567	No membrane orientation	1545:1567	No membrane orientation	1545:1567	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	9	64	theme	isotropic	2006:2014	arg1	components					2016:2025	identical composite isotropic components	1986:2025	identical composite isotropic components which were never characterized before	1986:2063	These bicelles are in particular associated with similar deuterium NMR spectra exhibiting identical composite isotropic components which were never characterized before.					
36913407	1	65	theme	membranes	249:257	arg1	studies					227:233	structural studies	216:233	structural studies of biological membranes	216:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	5	66	theme	gel	1261:1263	arg1	phase					1265:1269	the gel phase	1257:1269	the gel phase doped with only a small amount of the cyclodextrin derivative	1257:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	67	theme	complete	1151:1158	arg1	extinction					1160:1169	complete extinction	1151:1169	complete extinction at 13 °C	1151:1178	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	6	68	theme	ripple	1531:1536	arg1	phase					1538:1542	the Pβ' ripple phase	1523:1542	the Pβ' ripple phase	1523:1542	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	1	69	theme	isotropic	169:177	arg1	mimetics					203:210	useful isotropic or anisotropic membrane mimetics	162:210	useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes	162:257	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	4	70	theme	liposomes	1012:1020	arg1	layers					998:1003	the outer or inner layers	979:1003	the outer or inner layers of the liposomes	979:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	8	71	theme	bicellar	1790:1797	arg1	aggregates					1799:1808	possible DMPC bicellar aggregates	1776:1808	possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC)	1776:1893	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	8	71	theme	bicellar	1790:1797	arg1	those					1818:1822	those	1818:1822	those	1818:1822	The data are discussed in relation to the formation of possible DMPC bicellar aggregates such as those known to occur after insertion of dihexanoylphosphatidylcholine (DHPC).					
36913407	7	72	theme	important	1697:1705	arg1	perturbation					1707:1718	important perturbation	1697:1718	important perturbation	1697:1718	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	4	73	theme	outer	983:987	arg1	layers					998:1003	the outer or inner layers	979:1003	the outer or inner layers of the liposomes	979:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	4	74	theme	component	801:809	arg1	deconvolution					749:761	deconvolution	749:761	deconvolution of a broad composite 2H NMR isotropic component	749:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	7	75	theme	TrimβMLC	1680:1687	arg1	insertion					1667:1675	the insertion	1663:1675	the insertion of TrimβMLC	1663:1687	No membrane orientation and fragmentation was detected with unsaturated POPC membranes, which are able to accommodate the insertion of TrimβMLC without important perturbation.					
36913407	4	76	theme	inner	992:996	arg1	layers					998:1003	the outer or inner layers	979:1003	the outer or inner layers of the liposomes	979:1020	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	2	77	theme	magnetic	470:477	arg1	orientation					479:489	magnetic orientation	470:489	magnetic orientation	470:489	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	4	78	theme	composite	774:782	arg1	component					801:809	a broad composite 2H NMR isotropic component	766:809	a broad composite 2H NMR isotropic component	766:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	2	79	theme	lauryl	423:428	arg1	chain					435:439	a lauryl acyl chain	421:439	a lauryl acyl chain (TrimβMLC)	421:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	79	theme	lauryl	423:428	arg1	TrimβMLC					442:449	TrimβMLC	442:449	TrimβMLC	442:449	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	0	80	theme	Membranes	22:30	arg1	Fragmentation					0:12	Fragmentation	0:12	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.	0:104	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.					
36913407	5	81	theme	probable	1188:1195	arg1	release					1197:1203	a probable release	1186:1203	a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative	1186:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	1	82	theme	bilayer	112:118	arg1	aggregates					126:135	Small bilayer lipid aggregates	106:135	Small bilayer lipid aggregates such as bicelles	106:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	1	82	theme	bilayer	112:118	arg1	bicelles					145:152	bicelles	145:152	bicelles	145:152	Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic membrane mimetics for structural studies of biological membranes.					
36913407	4	83	theme	NMR	787:789	arg1	component					801:809	a broad composite 2H NMR isotropic component	766:809	a broad composite 2H NMR isotropic component	766:809	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	5	84	theme	cyclodextrin	1309:1320	arg1	derivative					1322:1331	the cyclodextrin derivative	1305:1331	the cyclodextrin derivative	1305:1331	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	3	85	theme	pure	667:670	arg1	TrimβMLC					672:679	pure TrimβMLC	667:679	pure TrimβMLC	667:679	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	4	86	theme	DMPC	841:844	arg1	membranes					846:854	the DMPC membranes	837:854	the DMPC membranes	837:854	After deconvolution of a broad composite 2H NMR isotropic component, we propose a model where the DMPC membranes are progressively disrupted by TrimβMLC into small and large micellar aggregates depending whether they are extracted from the outer or inner layers of the liposomes.					
36913407	0	87	theme	Amphiphilic	50:60	arg1	Cyclodextrin					62:73	a Wedge-Shaped Amphiphilic Cyclodextrin	35:73	a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates	35:103	Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates.					
36913407	5	88	theme	DMPC-d27	1065:1072	arg1	°C					1095:1096	Tc = 21.5 °C	1085:1096	Tc = 21.5 °C	1085:1096	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	5	88	theme	DMPC-d27	1065:1072	arg1	membranes					1074:1082	pure DMPC-d27 membranes	1060:1082	pure DMPC-d27 membranes (Tc = 21.5 °C)	1060:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36913407	3	89	theme	large	710:714	arg1	structures					731:740	large giant micellar structures	710:740	large giant micellar structures	710:740	The fragmentation process fully detailed in the present paper is observed with 20% cyclodextrin derivative below 37 °C, where pure TrimβMLC self-assembles in water into large giant micellar structures.					
36913407	6	90	theme	micellar	1477:1484	arg1	aggregates					1486:1495	micellar aggregates	1477:1495	micellar aggregates	1477:1495	Bilayer fragmentation between Tc and 13 °C was also observed with 10% and 5% of TrimβMLC, with NMR spectra suggesting possible interactions of micellar aggregates with fluid-like lipids of the Pβ' ripple phase.					
36913407	2	91	theme	βcyclodextrin	358:370	arg1	derivative					334:343	a wedge-shaped amphiphilic derivative	307:343	a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC)	307:450	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	2	91	theme	βcyclodextrin	358:370	arg1	able					455:458	able	455:458	able	455:458	We have shown previously by deuterium NMR that a wedge-shaped amphiphilic derivative of trimethyl βcyclodextrin anchored in deuterated DMPC-d27 bilayers through a lauryl acyl chain (TrimβMLC) is able to induce magnetic orientation and fragmentation of the multilamellar membranes.					
36913407	5	92	theme	fluid-to-gel	1033:1044	arg1	transition					1046:1055	the fluid-to-gel transition	1029:1055	the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C)	1029:1097	Below the fluid-to-gel transition of pure DMPC-d27 membranes (Tc = 21.5 °C), the micellar aggregates vanish progressively until complete extinction at 13 °C, with a probable release of pure TrimβMLC micelles leaving lipid bilayers in the gel phase doped with only a small amount of the cyclodextrin derivative.					
36418020	10	0	theme	group	2224:2228	arg1	reaction					2230:2237	isothiocyanate group reaction	2209:2237	isothiocyanate group reaction	2209:2237	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	9	1	theme	bioconjugation	2034:2047	arg1	examples					2049:2056	bioconjugation examples	2034:2056	bioconjugation examples	2034:2056	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	9	1	theme	bioconjugation	2034:2047	arg1	EPPT1					1876:1880	EPPT1	1876:1880	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation	1876:2005	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	3	2	theme	PFC	711:713	arg1	complexes					691:699	inclusion complexes	681:699	inclusion complexes of CD and PFC	681:713	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	2	3	theme	suitable	387:394	arg1	perfluorocarbons					396:411	suitable perfluorocarbons	387:411	suitable perfluorocarbons (PFCs)	387:418	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	2	3	theme	suitable	387:394	arg1	PFCs					414:417	PFCs	414:417	PFCs	414:417	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	5	4	theme	NMH	1162:1164	arg1	therapy					1166:1172	NMH therapy	1162:1172	NMH therapy	1162:1172	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	4	5	theme	various	1024:1030	arg1	CD					1032:1033	various CD and PFC derivatives	1024:1053	CD	1032:1033	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	12	6	theme	noninvasive	2676:2686	arg1	NMH					2658:2660	NMH	2658:2660	NMH	2658:2660	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	6	theme	noninvasive	2676:2686	arg1	method					2697:2702	a targeted noninvasive ablation method	2665:2702	a targeted noninvasive ablation method	2665:2702	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	4	7	with	powder	989:994	arg1	content					1010:1016	high PFC content	1001:1016	high PFC content among various CD and PFC derivatives	1001:1053	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	8	8	theme	functional	1827:1836	arg1	precursors					1846:1855	precursors	1846:1855	precursors of bioconjugation	1846:1873	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	8	theme	functional	1827:1836	arg1	NCCs					1838:1841	functional NCCs	1827:1841	functional NCCs	1827:1841	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	2	9	theme	FDA-approved	351:362	arg1	CD					379:380	CD	379:380	CD	379:380	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	2	9	theme	FDA-approved	351:362	arg1	cyclodextrins					364:376	FDA-approved cyclodextrins	351:376	FDA-approved cyclodextrins (CD)	351:381	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	7	10	theme	effective	1567:1575	arg1	reaction					1616:1623	the "click" reaction	1604:1623	the "click" reaction	1604:1623	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	7	10	theme	effective	1567:1575	arg1	coupling					1721:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	7	10	theme	effective	1567:1575	arg1	reactions					1586:1594	effective coupling reactions	1567:1594	effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1567:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	7	11	theme	EDC/NHS	1712:1718	arg1	coupling					1721:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	11	12	theme	obtained	2244:2251	arg1	bioconjugates					2253:2265	The obtained bioconjugates	2240:2265	The obtained bioconjugates	2240:2265	The obtained bioconjugates were tested in vitro to validate the conjugation, and the ability to lower the histotripsy cavitation threshold, which is necessary for NMH, was demonstrated for all bioconjugates.					
36418020	3	13	theme	aggregate	751:759	arg1	behavior					761:768	their aggregate behavior	745:768	their aggregate behavior	745:768	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	6	14	theme	bioconjugation	1273:1286	arg1	potential					1288:1296	the bioconjugation potential	1269:1296	the bioconjugation potential of NCCs	1269:1304	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	4	15	theme	PFC	1006:1008	arg1	content					1010:1016	high PFC content	1001:1016	high PFC content among various CD and PFC derivatives	1001:1053	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	12	16	theme	improved	2632:2639	arg1	tools					2641:2645	improved tools	2632:2645	improved tools	2632:2645	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	16	theme	improved	2632:2639	arg1	metrics					2612:2618	the desired bioconjugation metrics	2585:2618	the desired bioconjugation metrics	2585:2618	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	17	theme	bioconjugation	2597:2610	arg1	tools					2641:2645	improved tools	2632:2645	improved tools	2632:2645	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	17	theme	bioconjugation	2597:2610	arg1	metrics					2612:2618	the desired bioconjugation metrics	2585:2618	the desired bioconjugation metrics	2585:2618	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	3	18	theme	computational	612:624	arg1	studies					626:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	1	19	theme	new-generation	159:172	arg1	agents					174:179	new-generation agents	159:179	new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs)	159:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	19	theme	new-generation	159:172	arg1	clusters					139:146	Nanocone clusters	130:146	Nanocone clusters (NCCs)	130:153	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	7	20	theme	-N'-ethylcarbodiimide	1654:1674	arg1	coupling					1721:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	10	21	theme	NCC	2168:2170	arg1	reaction					2172:2179	alkyne functional NCC reaction	2150:2179	alkyne functional NCC reaction	2150:2179	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	11	22	theme	cavitation	2358:2367	arg1	threshold					2369:2377	the histotripsy cavitation threshold	2342:2377	the histotripsy cavitation threshold	2342:2377	The obtained bioconjugates were tested in vitro to validate the conjugation, and the ability to lower the histotripsy cavitation threshold, which is necessary for NMH, was demonstrated for all bioconjugates.					
36418020	3	23	theme	CD	847:848	arg1	derivatives					850:860	CD derivatives	847:860	CD derivatives	847:860	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	0	24	theme	Nanoparticle-Mediated	95:115	arg1	Histotripsy					117:127	Nanoparticle-Mediated Histotripsy	95:127	Nanoparticle-Mediated Histotripsy	95:127	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	1	25	theme	histotripsy	206:216	arg1	agents					174:179	new-generation agents	159:179	new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs)	159:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	25	theme	histotripsy	206:216	arg1	clusters					139:146	Nanocone clusters	130:146	Nanocone clusters (NCCs)	130:153	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	10	26	theme	fluorescein	2112:2122	arg1	isothiocyanate					2124:2137	fluorescein isothiocyanate	2112:2137	fluorescein isothiocyanate (FITC)	2112:2144	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	10	26	theme	fluorescein	2112:2122	arg1	FITC					2140:2143	FITC	2140:2143	FITC	2140:2143	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	10	27	theme	alkyne	2150:2155	arg1	reaction					2172:2179	alkyne functional NCC reaction	2150:2179	alkyne functional NCC reaction	2150:2179	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	8	28	theme	building	1770:1777	arg1	blocks					1779:1784	building blocks	1770:1784	building blocks of NCCs	1770:1792	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	28	theme	building	1770:1777	arg1	βCDs					1752:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	7	29	theme	click	1609:1613	arg1	reaction					1616:1623	the "click" reaction	1604:1623	the "click" reaction	1604:1623	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	0	30	theme	Functional	66:75	arg1	Clusters					54:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	0	30	theme	Functional	66:75	arg1	Nanoparticles					77:89	Functional Nanoparticles	66:89	Functional Nanoparticles for Nanoparticle-Mediated Histotripsy	66:127	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	1	31	theme	Nanocone	130:137	arg1	agents					174:179	new-generation agents	159:179	new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs)	159:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	31	theme	Nanocone	130:137	arg1	NCCs					149:152	NCCs	149:152	NCCs	149:152	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	31	theme	Nanocone	130:137	arg1	clusters					139:146	Nanocone clusters	130:146	Nanocone clusters (NCCs)	130:153	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	8	32	used	used	1762:1765	arg2	βCDs					1752:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	32	used	used	1762:1765	arg2	blocks					1779:1784	building blocks	1770:1784	building blocks of NCCs	1770:1792	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	2	33	theme	detectable	462:471	arg1	amount					477:482	detectable PFC amount	462:482	detectable PFC amount	462:482	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	9	34	theme	used	1964:1967	arg1	agent					1979:1983	the most commonly used targeting agent	1946:1983	the most commonly used targeting agent along with PEGylation	1946:2005	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	0	35	theme	Nanocone	45:52	arg1	Clusters					54:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	0	35	theme	Nanocone	45:52	arg1	Nanoparticles					77:89	Functional Nanoparticles	66:89	Functional Nanoparticles for Nanoparticle-Mediated Histotripsy	66:127	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	11	36	theme	histotripsy	2346:2356	arg1	threshold					2369:2377	the histotripsy cavitation threshold	2342:2377	the histotripsy cavitation threshold	2342:2377	The obtained bioconjugates were tested in vitro to validate the conjugation, and the ability to lower the histotripsy cavitation threshold, which is necessary for NMH, was demonstrated for all bioconjugates.					
36418020	7	37	theme	coupling	1577:1584	arg1	reaction					1616:1623	the "click" reaction	1604:1623	the "click" reaction	1604:1623	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	7	37	theme	coupling	1577:1584	arg1	coupling					1721:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	7	37	theme	coupling	1577:1584	arg1	reactions					1586:1594	effective coupling reactions	1567:1594	effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1567:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	2	38	theme	stable	494:499	arg1	storage					511:517	more stable long-term storage	489:517	more stable long-term storage	489:517	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	3	39	from	solubility	833:842	arg1	localization					785:796	the localization	781:796	the localization of PFC in the cavity and the water solubility of CD derivatives	781:860	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	3	40	theme	inclusion	681:689	arg1	complexes					691:699	inclusion complexes	681:699	inclusion complexes of CD and PFC	681:713	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	2	41	theme	smaller	437:443	arg1	aggregates					450:459	smaller size aggregates	437:459	smaller size aggregates	437:459	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	6	42	theme	functionalization	1352:1368	arg1	PEGylation					1397:1406	PEGylation	1397:1406	PEGylation	1397:1406	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	42	theme	functionalization	1352:1368	arg1	methods					1370:1376	the most commonly used functionalization methods	1329:1376	the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling	1329:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	42	theme	functionalization	1352:1368	arg1	targeting					1386:1394	targeting	1386:1394	targeting	1386:1394	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	42	theme	functionalization	1352:1368	arg1	labeling					1425:1432	fluorescent labeling	1413:1432	fluorescent labeling	1413:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	5	43	theme	NCC	1118:1120	arg1	composition					1122:1132	the selected NCC composition	1105:1132	the selected NCC composition	1105:1132	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	4	44	theme	PFC	1039:1041	arg1	derivatives					1043:1053	various CD and PFC derivatives	1024:1053	derivatives	1043:1053	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	3	45	from	cavity	812:817	arg1	localization					785:796	the localization	781:796	the localization of PFC in the cavity and the water solubility of CD derivatives	781:860	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	12	46	theme	desired	2589:2595	arg1	tools					2641:2645	improved tools	2632:2645	improved tools	2632:2645	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	46	theme	desired	2589:2595	arg1	metrics					2612:2618	the desired bioconjugation metrics	2585:2618	the desired bioconjugation metrics	2585:2618	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	47	theme	obtained	2485:2492	arg1	bioconjugates					2494:2506	all obtained bioconjugates	2481:2506	all obtained bioconjugates	2481:2506	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	1	48	theme	nanodroplets	293:304	arg1	limitations					258:268	the limitations	254:268	the limitations of previously designed nanodroplets (NDs)	254:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	3	49	theme	PFC	727:729	arg1	droplets					731:738	free PFC droplets	722:738	free PFC droplets	722:738	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	10	50	theme	isothiocyanate	2209:2222	arg1	reaction					2230:2237	isothiocyanate group reaction	2209:2237	isothiocyanate group reaction	2209:2237	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	8	51	theme	PFH	1813:1815	arg1	presence					1801:1808	the presence	1797:1808	the presence of PFH to obtain functional NCCs as precursors of bioconjugation	1797:1873	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	5	52	theme	therapy	1166:1172	arg1	potential					1149:1157	the potential	1145:1157	the potential of NMH therapy	1145:1172	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	12	53	theme	targeted	2667:2674	arg1	NMH					2658:2660	NMH	2658:2660	NMH	2658:2660	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	53	theme	targeted	2667:2674	arg1	method					2697:2702	a targeted noninvasive ablation method	2665:2702	a targeted noninvasive ablation method	2665:2702	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	3	54	theme	Previous	586:593	arg1	studies					626:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	12	55	theme	ablation	2688:2695	arg1	NMH					2658:2660	NMH	2658:2660	NMH	2658:2660	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	12	55	theme	ablation	2688:2695	arg1	method					2697:2702	a targeted noninvasive ablation method	2665:2702	a targeted noninvasive ablation method	2665:2702	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	10	56	theme	labeled	2081:2087	arg1	NCCs					2089:2092	fluorescently labeled NCCs	2067:2092	fluorescently labeled NCCs	2067:2092	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	12	57	theme	threshold	2544:2552	arg1	pressure					2554:2561	the cavitation threshold pressure	2529:2561	the cavitation threshold pressure	2529:2561	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	3	58	theme	experimental	595:606	arg1	studies					626:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies	586:632	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	8	59	theme	bioconjugation	1860:1873	arg1	precursors					1846:1855	precursors	1846:1855	precursors of bioconjugation	1846:1873	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	59	theme	bioconjugation	1860:1873	arg1	NCCs					1838:1841	functional NCCs	1827:1841	functional NCCs	1827:1841	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	7	60	theme	amine	1539:1543	arg1	groups					1545:1550	amine groups	1539:1550	amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1539:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	9	61	theme	synthetic	1887:1895	arg1	peptide					1897:1903	a synthetic peptide	1885:1903	a synthetic peptide specific to uMUC1 and folic acid (FA)	1885:1941	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	3	62	theme	PFC	801:803	arg1	localization					785:796	the localization	781:796	the localization of PFC in the cavity and the water solubility of CD derivatives	781:860	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	9	63	theme	specific	1905:1912	arg1	peptide					1897:1903	a synthetic peptide	1885:1903	a synthetic peptide specific to uMUC1 and folic acid (FA)	1885:1941	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	12	64	theme	cavitation	2533:2542	arg1	pressure					2554:2561	the cavitation threshold pressure	2529:2561	the cavitation threshold pressure	2529:2561	Overall, the results showed that all obtained bioconjugates successfully lowered the cavitation threshold pressure while also fulfilling the desired bioconjugation metrics to serve as improved tools to enhance NMH as a targeted noninvasive ablation method.					
36418020	7	65	theme	hydrochloride/N-hydroxysuccinimide	1676:1709	arg1	coupling					1721:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling	1629:1728	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	1	66	theme	nanoparticle-mediated	184:204	arg1	histotripsy					206:216	nanoparticle-mediated histotripsy	184:216	nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs)	184:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	66	theme	nanoparticle-mediated	184:204	arg1	NMH					219:221	NMH	219:221	NMH	219:221	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	3	67	theme	derivatives	850:860	arg1	cavity					812:817	the cavity	808:817	the cavity	808:817	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	3	67	theme	derivatives	850:860	arg1	solubility					833:842	the water solubility	823:842	the water solubility	823:842	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	9	68	theme	folic	1927:1931	arg1	FA					1939:1940	FA	1939:1940	FA	1939:1940	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	9	68	theme	folic	1927:1931	arg1	acid					1933:1936	folic acid	1927:1936	folic acid (FA)	1927:1941	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	5	69	theme	future	1208:1213	arg1	experiments					1215:1225	more detailed future experiments	1194:1225	more detailed future experiments	1194:1225	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	5	70	theme	further	1082:1088	arg1	development					1090:1100	the further development	1078:1100	the further development of the selected NCC composition	1078:1132	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	8	71	theme	monofunctional	1737:1750	arg1	blocks					1779:1784	building blocks	1770:1784	building blocks of NCCs	1770:1792	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	71	theme	monofunctional	1737:1750	arg1	βCDs					1752:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	3	72	from	localization	785:796	arg1	cavity					812:817	the cavity	808:817	the cavity	808:817	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	3	72	from	localization	785:796	arg1	solubility					833:842	the water solubility	823:842	the water solubility	823:842	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	10	73	theme	functional	2157:2166	arg1	reaction					2172:2179	alkyne functional NCC reaction	2150:2179	alkyne functional NCC reaction	2150:2179	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	2	74	dep	stable	494:499	arg1	long-term					501:509	long-term	501:509	long-term	501:509	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	3	75	from	PFC	801:803	arg1	cavity					812:817	the cavity	808:817	the cavity	808:817	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	3	75	from	PFC	801:803	arg1	solubility					833:842	the water solubility	823:842	the water solubility	823:842	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	3	76	theme	water	827:831	arg1	solubility					833:842	the water solubility	823:842	the water solubility	823:842	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	6	77	theme	NCCs	1301:1304	arg1	potential					1288:1296	the bioconjugation potential	1269:1296	the bioconjugation potential of NCCs	1269:1304	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	7	78	theme	"	1614:1614	arg1	reaction					1616:1623	the "click" reaction	1604:1623	the "click" reaction	1604:1623	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	2	79	theme	obtained	529:536	arg1	powder					538:543	the obtained powder	525:543	the obtained powder	525:543	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	10	80	theme	propargyl	2189:2197	arg1	amine					2199:2203	propargyl amine	2189:2203	propargyl amine	2189:2203	Lastly, fluorescently labeled NCCs were obtained via fluorescein isothiocyanate (FITC) and alkyne functional NCC reaction through propargyl amine and isothiocyanate group reaction.					
36418020	0	81	theme	β-Cyclodextrin-Perfluorohexane	14:43	arg1	Clusters					54:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	β-Cyclodextrin-Perfluorohexane Nanocone Clusters	14:61	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	0	81	theme	β-Cyclodextrin-Perfluorohexane	14:43	arg1	Nanoparticles					77:89	Functional Nanoparticles	66:89	Functional Nanoparticles for Nanoparticle-Mediated Histotripsy	66:127	Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy.					
36418020	2	82	theme	PFC	473:475	arg1	amount					477:482	detectable PFC amount	462:482	detectable PFC amount	462:482	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	8	83	theme	NCCs	1789:1792	arg1	blocks					1779:1784	building blocks	1770:1784	building blocks of NCCs	1770:1792	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	8	83	theme	NCCs	1789:1792	arg1	βCDs					1752:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs	1731:1755	These monofunctional βCDs were used as building blocks of NCCs in the presence of PFH to obtain functional NCCs as precursors of bioconjugation.					
36418020	4	84	theme	high	1001:1004	arg1	content					1010:1016	high PFC content	1001:1016	high PFC content among various CD and PFC derivatives	1001:1053	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	9	85	theme	targeting	1969:1977	arg1	agent					1979:1983	the most commonly used targeting agent	1946:1983	the most commonly used targeting agent along with PEGylation	1946:2005	EPPT1 as a synthetic peptide specific to uMUC1 and folic acid (FA) as the most commonly used targeting agent along with PEGylation were successfully shown as bioconjugation examples.					
36418020	2	86	theme	size	445:448	arg1	aggregates					450:459	smaller size aggregates	437:459	smaller size aggregates	437:459	NCCs can be obtained by simply mixing FDA-approved cyclodextrins (CD) and suitable perfluorocarbons (PFCs), which result in smaller size aggregates, detectable PFC amount, and more stable long-term storage since the obtained powder can be stored and redispersed as needed.					
36418020	6	87	theme	methods	1370:1376	arg1	example					1318:1324	the example	1314:1324	the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling	1314:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	4	88	theme	ideal	937:941	arg1	perfluorohexane					911:925	perfluorohexane	911:925	perfluorohexane (PFH)	911:931	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	4	88	theme	ideal	937:941	arg1	β-cyclodextrin					886:899	β-cyclodextrin	886:899	β-cyclodextrin (βCD)	886:905	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	4	88	theme	ideal	937:941	arg1	candidates					943:952	ideal candidates	937:952	ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives	937:1053	It has been shown that β-cyclodextrin (βCD) and perfluorohexane (PFH) are ideal candidates for NCCs that can be isolated as a powder with high PFC content among various CD and PFC derivatives.					
36418020	6	89	theme	used	1347:1350	arg1	PEGylation					1397:1406	PEGylation	1397:1406	PEGylation	1397:1406	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	89	theme	used	1347:1350	arg1	methods					1370:1376	the most commonly used functionalization methods	1329:1376	the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling	1329:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	89	theme	used	1347:1350	arg1	targeting					1386:1394	targeting	1386:1394	targeting	1386:1394	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	6	89	theme	used	1347:1350	arg1	labeling					1425:1432	fluorescent labeling	1413:1432	fluorescent labeling	1413:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	5	90	theme	selected	1109:1116	arg1	composition					1122:1132	the selected NCC composition	1105:1132	the selected NCC composition	1105:1132	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	7	91	theme	building	1462:1469	arg1	block					1471:1475	a building block	1460:1475	a building block	1460:1475	For this purpose, βCD as a building block was monofunctionalized with groups such as azide, alkyne, and amine groups that allow for effective coupling reactions such as the "click" reaction and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) coupling.					
36418020	3	92	theme	CD	704:705	arg1	complexes					691:699	inclusion complexes	681:699	inclusion complexes of CD and PFC	681:713	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	5	93	theme	composition	1122:1132	arg1	development					1090:1100	the further development	1078:1100	the further development of the selected NCC composition	1078:1132	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36418020	3	94	theme	complexes	691:699	arg1	organization					665:676	an organization	662:676	an organization of inclusion complexes of CD and PFC around free PFC droplets	662:738	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	1	95	theme	designed	284:291	arg1	nanodroplets					293:304	previously designed nanodroplets	273:304	previously designed nanodroplets (NDs)	273:310	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	1	95	theme	designed	284:291	arg1	NDs					307:309	NDs	307:309	NDs	307:309	Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs).					
36418020	3	96	theme	free	722:725	arg1	droplets					731:738	free PFC droplets	722:738	free PFC droplets	722:738	Previous experimental and computational studies showed that NCCs consist of an organization of inclusion complexes of CD and PFC around free PFC droplets, and their aggregate behavior depends on the localization of PFC in the cavity and the water solubility of CD derivatives.					
36418020	6	97	theme	fluorescent	1413:1423	arg1	labeling					1425:1432	fluorescent labeling	1413:1432	fluorescent labeling	1413:1432	It is aimed to show the bioconjugation potential of NCCs through the example of the most commonly used functionalization methods such as targeting, PEGylation, and fluorescent labeling.					
36418020	5	98	theme	detailed	1199:1206	arg1	experiments					1215:1225	more detailed future experiments	1194:1225	more detailed future experiments	1194:1225	This study focuses on the further development of the selected NCC composition to enhance the potential of NMH therapy while also enabling more detailed future experiments in vitro and in vivo.					
36171502	7	0	theme	metabolite	1434:1443	arg1	accumulation					1445:1456	metabolite accumulation	1434:1456	metabolite accumulation	1434:1456	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	6	1	theme	total	1078:1082	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	1	theme	total	1078:1082	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	4	2	theme	leaf	595:598	arg1	explants					600:607	leaf explants	595:607	leaf explants	595:607	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	3	with	sucrose	710:716	arg1	roots					785:789	12.9 roots	780:789	12.9 roots per explant	780:801	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	3	with	sucrose	710:716	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	8	4	theme	wild	1654:1657	arg1	resources					1659:1667	wild resources	1654:1667	wild resources	1654:1667	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	10	5	dep	atractylon	1814:1823	arg1	the					1810:1812	the	1810:1812	the	1810:1812	• Suspension culture was optimized for the atractylon and β-eudesmol production.					
36171502	7	6	theme	auxins	1363:1368	arg1	types					1354:1358	different types	1344:1358	different types of auxins in the suspension culture	1344:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	7	7	theme	central	1269:1275	arg1	experiment					1294:1303	the central composite design experiment	1265:1303	the central composite design experiment	1265:1303	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	4	8	theme	1.5 mg/L	661:668	arg1	NAA					694:696	NAA	694:696	NAA	694:696	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	8	theme	1.5 mg/L	661:668	arg1	acid					688:691	1.5 mg/L naphthaleneacetic acid	661:691	1.5 mg/L naphthaleneacetic acid (NAA)	661:697	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	7	9	from	culture	1388:1394	arg1	types					1354:1358	different types	1344:1358	different types of auxins in the suspension culture	1344:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	7	10	theme	types	1354:1358	arg1	use					1337:1339	the combined use	1324:1339	the combined use of different types of auxins in the suspension culture	1324:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	1	11	theme	gastric	184:190	arg1	disorders					192:200	gastric disorders	184:200	gastric disorders	184:200	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	5	12	theme	root	828:831	arg1	culture					844:850	the adventitious root suspension culture	811:850	the adventitious root suspension culture	811:850	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	7	13	theme	combined	1328:1335	arg1	use					1337:1339	the combined use	1324:1339	the combined use of different types of auxins in the suspension culture	1324:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	6	14	theme	total	1044:1048	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	14	theme	total	1044:1048	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	11	15	theme	metabolite	1912:1921	arg1	accumulation					1923:1934	metabolite accumulation	1912:1934	metabolite accumulation	1912:1934	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	6	16	theme	3.2 mg/L	1188:1195	arg1	NAA					1197:1199	3.2 mg/L NAA	1188:1199	3.2 mg/L NAA	1188:1199	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	17	theme	8 g/L	1250:1254	arg1	density					1239:1245	the inoculum density	1226:1245	the inoculum density of 8 g/L	1226:1254	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	10	18	theme	Suspension	1773:1782	arg1	culture					1784:1790	• Suspension culture	1771:1790	• Suspension culture	1771:1790	• Suspension culture was optimized for the atractylon and β-eudesmol production.					
36171502	5	19	theme	compounds	912:920	arg1	content					890:896	the accumulated content	874:896	the accumulated content of the target compounds	874:920	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	5	19	theme	compounds	912:920	arg1	biomass					862:868	the root biomass	853:868	the root biomass	853:868	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	7	20	from	types	1354:1358	arg1	culture					1388:1394	the suspension culture	1373:1394	the suspension culture	1373:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	7	21	from	auxins	1363:1368	arg1	culture					1388:1394	the suspension culture	1373:1394	the suspension culture	1373:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	0	22	from	production	9:18	arg1	chinensis					67:75	chinensis	67:75	chinensis	67:75	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	9	23	theme	induction	1709:1717	arg1	culture					1719:1725	• The induction culture	1703:1725	• The induction culture	1703:1725	KEY POINTS: • The induction culture was optimized for efficient root induction.					
36171502	0	24	theme	root	93:96	arg1	culture					98:104	adventitious root culture	80:104	adventitious root culture	80:104	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	7	25	theme	suspension	1377:1386	arg1	culture					1388:1394	the suspension culture	1373:1394	the suspension culture	1373:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	5	26	theme	maximum	960:966	arg1	values					968:973	the maximum values	956:973	the maximum values after 8 weeks of culture	956:998	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	7	27	theme	auxin	1499:1503	arg1	type					1491:1494	only one type	1482:1494	only one type of auxin	1482:1503	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	2	28	dep	in	361:362	arg1	vitro					364:368	vitro	364:368	vitro	364:368	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	2	29	theme	atractylon	384:393	arg1	production					370:379	in vitro production	361:379	in vitro production of atractylon and β-eudesmol	361:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	6	30	theme	3.38 mg/g	1064:1072	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	30	theme	3.38 mg/g	1064:1072	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	1	31	theme	medicinal	135:143	arg1	chinensis					120:128	Atractylodes chinensis	107:128	Atractylodes chinensis	107:128	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	1	31	theme	medicinal	135:143	arg1	plant					145:149	a medicinal plant	133:149	a medicinal plant widely used for the treatment of gastric disorders	133:200	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	4	32	theme	root	735:738	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	3	33	theme	main	415:418	arg1	parameters					420:429	The main parameters	411:429	The main parameters in the adventitious root induction and suspension cultures	411:488	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	0	34	theme	In	0:1	arg1	production					9:18	In vitro production	0:18	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.	0:105	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	7	35	theme	composite	1277:1285	arg1	experiment					1294:1303	the central composite design experiment	1265:1303	the central composite design experiment	1265:1303	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	9	36	theme	root	1755:1758	arg1	induction					1760:1768	efficient root induction	1745:1768	efficient root induction	1745:1768	KEY POINTS: • The induction culture was optimized for efficient root induction.					
36171502	11	37	theme	auxins	1880:1885	arg1	use					1863:1865	• Combined use	1852:1865	• Combined use of different auxins	1852:1885	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	6	38	theme	MS	1139:1140	arg1	medium					1149:1154	½ MS liquid medium	1137:1154	½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L	1137:1254	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	1	39	theme	Atractylodes	107:118	arg1	chinensis					120:128	Atractylodes chinensis	107:128	Atractylodes chinensis	107:128	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	1	39	theme	Atractylodes	107:118	arg1	plant					145:149	a medicinal plant	133:149	a medicinal plant widely used for the treatment of gastric disorders	133:200	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	6	40	theme	compounds	1033:1041	arg1	yield					1013:1017	The maximum yield	1001:1017	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg)	1001:1097	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	2	41	theme	β-eudesmol	399:408	arg1	production					370:379	in vitro production	361:379	in vitro production of atractylon and β-eudesmol	361:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	3	42	theme	adventitious	438:449	arg1	induction					456:464	the adventitious root induction	434:464	the adventitious root induction	434:464	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	0	43	theme	atractylon	23:32	arg1	production					9:18	In vitro production	0:18	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.	0:105	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	0	44	theme	β-eudesmol	38:47	arg1	production					9:18	In vitro production	0:18	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.	0:105	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	4	45	theme	Adventitious	541:552	arg1	roots					554:558	Adventitious roots	541:558	Adventitious roots	541:558	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	10	46	theme	β-eudesmol	1829:1838	arg1	production					1840:1849	β-eudesmol production	1829:1849	β-eudesmol production	1829:1849	• Suspension culture was optimized for the atractylon and β-eudesmol production.					
36171502	3	47	theme	suspension	470:479	arg1	cultures					481:488	suspension cultures	470:488	suspension cultures	470:488	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	8	48	theme	industrial	1581:1590	arg1	production					1592:1601	the industrial production	1577:1601	the industrial production of A. chinensis pharmaceuticals	1577:1633	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	1	49	theme	main	211:214	arg1	compounds					226:234	its main bioactive compounds	207:234	its main bioactive compounds	207:234	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	1	49	theme	main	211:214	arg1	atractylon					240:249	atractylon	240:249	atractylon	240:249	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	4	50	theme	Murashige	612:620	arg1	medium					643:648	Murashige and Skoog (MS) solid medium	612:648	medium	643:648	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	11	51	theme	different	1870:1878	arg1	auxins					1880:1885	different auxins	1870:1885	different auxins	1870:1885	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	3	52	from	parameters	420:429	arg1	induction					456:464	the adventitious root induction	434:464	the adventitious root induction	434:464	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	3	52	from	parameters	420:429	arg1	cultures					481:488	suspension cultures	470:488	suspension cultures	470:488	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	2	53	theme	in	361:362	arg1	production					370:379	in vitro production	361:379	in vitro production of atractylon and β-eudesmol	361:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	0	54	dep	In	0:1	arg1	vitro					3:7	vitro	3:7	vitro	3:7	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	6	55	theme	yield	1084:1088	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	55	theme	yield	1084:1088	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	4	56	theme	Skoog	626:630	arg1	medium					643:648	Murashige and Skoog (MS) solid medium	612:648	medium	643:648	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	2	57	theme	chinensis	347:355	arg1	system					334:339	the adventitious root culture system	304:339	the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol	304:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	8	58	theme	chinensis	1609:1617	arg1	pharmaceuticals					1619:1633	A. chinensis pharmaceuticals	1606:1633	A. chinensis pharmaceuticals	1606:1633	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	7	59	theme	root	1418:1421	arg1	growth					1423:1428	root growth	1418:1428	root growth	1418:1428	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	8	60	theme	promising	1553:1561	arg1	candidate					1563:1571	a promising candidate	1551:1571	a promising candidate for the industrial production of A. chinensis pharmaceuticals	1551:1633	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	6	61	theme	inoculum	1230:1237	arg1	density					1239:1245	the inoculum density	1226:1245	the inoculum density of 8 g/L	1226:1254	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	62	theme	liquid	1142:1147	arg1	medium					1149:1154	½ MS liquid medium	1137:1154	½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L	1137:1254	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	63	theme	½	1137:1137	arg1	medium					1149:1154	½ MS liquid medium	1137:1154	½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L	1137:1254	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	64	theme	40 g/L	1206:1211	arg1	sucrose					1213:1219	40 g/L sucrose	1206:1219	40 g/L sucrose	1206:1219	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	2	65	theme	adventitious	308:319	arg1	system					334:339	the adventitious root culture system	304:339	the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol	304:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	5	66	theme	root	857:860	arg1	biomass					862:868	the root biomass	853:868	the root biomass	853:868	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	4	67	theme	naphthaleneacetic	670:686	arg1	NAA					694:696	NAA	694:696	NAA	694:696	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	67	theme	naphthaleneacetic	670:686	arg1	acid					688:691	1.5 mg/L naphthaleneacetic acid	661:691	1.5 mg/L naphthaleneacetic acid (NAA)	661:697	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	8	68	theme	field	1672:1676	arg1	cultivation					1678:1688	field cultivation	1672:1688	field cultivation	1672:1688	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	5	69	theme	adventitious	815:826	arg1	culture					844:850	the adventitious root suspension culture	811:850	the adventitious root suspension culture	811:850	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	7	70	theme	different	1344:1352	arg1	types					1354:1358	different types	1344:1358	different types of auxins in the suspension culture	1344:1394	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	4	71	theme	MS	633:634	arg1	medium					643:648	Murashige and Skoog (MS) solid medium	612:648	medium	643:648	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	9	72	dep	POINTS	1695:1700	arg1	optimized					1731:1739	optimized	1731:1739	was optimized for efficient root induction	1727:1768	KEY POINTS: • The induction culture was optimized for efficient root induction.					
36171502	5	73	theme	suspension	833:842	arg1	culture					844:850	the adventitious root suspension culture	811:850	the adventitious root suspension culture	811:850	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	0	74	from	chinensis	67:75	arg1	production					9:18	In vitro production	0:18	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.	0:105	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	0	74	from	chinensis	67:75	arg1	β-eudesmol					38:47	β-eudesmol	38:47	β-eudesmol	38:47	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	0	74	from	chinensis	67:75	arg1	atractylon					23:32	atractylon	23:32	atractylon	23:32	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	4	75	theme	solid	637:641	arg1	medium					643:648	Murashige and Skoog (MS) solid medium	612:648	medium	643:648	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	11	76	theme	root	1896:1899	arg1	growth					1901:1906	root growth	1896:1906	root growth	1896:1906	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	4	77	theme	30 g/L	703:708	arg1	sucrose					710:716	30 g/L sucrose	703:716	30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant	703:801	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	5	78	theme	target	905:910	arg1	compounds					912:920	the target compounds	901:920	the target compounds	901:920	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	9	79	theme	KEY	1691:1693	arg1	POINTS					1695:1700	KEY POINTS	1691:1700	KEY POINTS: • The induction culture was optimized for efficient root induction.	1691:1769	KEY POINTS: • The induction culture was optimized for efficient root induction.					
36171502	6	80	theme	2.0 mg/L	1174:1181	arg1	IBA					1183:1185	2.0 mg/L IBA	1174:1185	2.0 mg/L IBA	1174:1185	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	2	81	theme	culture	326:332	arg1	system					334:339	the adventitious root culture system	304:339	the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol	304:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	10	82	theme	•	1771:1771	arg1	culture					1784:1790	• Suspension culture	1771:1790	• Suspension culture	1771:1790	• Suspension culture was optimized for the atractylon and β-eudesmol production.					
36171502	1	83	theme	disorders	192:200	arg1	treatment					171:179	the treatment	167:179	the treatment of gastric disorders	167:200	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	6	84	theme	maximum	1005:1011	arg1	yield					1013:1017	The maximum yield	1001:1017	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg)	1001:1097	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	0	85	theme	adventitious	80:91	arg1	culture					98:104	adventitious root culture	80:104	adventitious root culture	80:104	In vitro production of atractylon and β-eudesmol from Atractylodes chinensis by adventitious root culture.					
36171502	5	86	theme	accumulated	878:888	arg1	content					890:896	the accumulated content	874:896	the accumulated content of the target compounds	874:920	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	7	87	theme	design	1287:1292	arg1	experiment					1294:1303	the central composite design experiment	1265:1303	the central composite design experiment	1265:1303	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	6	88	dep	compounds	1033:1041	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	88	dep	compounds	1033:1041	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	89	theme	concentration	1050:1062	arg1	2.66 mg					1090:1096	total yield 2.66 mg	1078:1096	total yield 2.66 mg	1078:1096	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	6	89	theme	concentration	1050:1062	arg1	DW					1074:1075	total concentration 3.38 mg/g DW	1044:1075	total concentration 3.38 mg/g DW	1044:1075	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	9	90	theme	efficient	1745:1753	arg1	induction					1760:1768	efficient root induction	1745:1768	efficient root induction	1745:1768	KEY POINTS: • The induction culture was optimized for efficient root induction.					
36171502	4	91	theme	highest	727:733	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	11	92	theme	•	1852:1852	arg1	use					1863:1865	• Combined use	1852:1865	• Combined use of different auxins	1852:1885	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	4	93	theme	%	774:774	arg1	roots					785:789	12.9 roots	780:789	12.9 roots per explant	780:801	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	93	theme	%	774:774	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	94	with	acid	688:691	arg1	roots					785:789	12.9 roots	780:789	12.9 roots per explant	780:801	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	94	with	acid	688:691	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	95	theme	induction	740:748	arg1	rate					750:753	the highest root induction rate	723:753	the highest root induction rate of approximately 92%	723:774	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	7	96	theme	type	1491:1494	arg1	application					1467:1477	the application	1463:1477	the application of only one type of auxin	1463:1503	Through the central composite design experiment, it was found that the combined use of different types of auxins in the suspension culture could further improve root growth and metabolite accumulation than the application of only one type of auxin.					
36171502	6	97	theme	target	1026:1031	arg1	compounds					1033:1041	the target compounds	1022:1041	the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg)	1022:1097	The maximum yield of the target compounds (total concentration 3.38 mg/g DW, total yield 2.66 mg) was achieved in the roots cultured in ½ MS liquid medium supplemented with 2.0 mg/L IBA, 3.2 mg/L NAA, and 40 g/L sucrose with the inoculum density of 8 g/L.					
36171502	11	98	theme	Combined	1854:1861	arg1	use					1863:1865	• Combined use	1852:1865	• Combined use of different auxins	1852:1885	• Combined use of different auxins improves root growth and metabolite accumulation.					
36171502	3	99	theme	root	451:454	arg1	induction					456:464	the adventitious root induction	434:464	the adventitious root induction	434:464	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	8	100	theme	new	1527:1529	arg1	possibility					1531:1541	a new possibility	1525:1541	a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation	1525:1688	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
36171502	4	101	contain	containing	650:659	arg2	acid					688:691	1.5 mg/L naphthaleneacetic acid	661:691	1.5 mg/L naphthaleneacetic acid (NAA)	661:697	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	101	contain	containing	650:659	arg2	sucrose					710:716	30 g/L sucrose	703:716	30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant	703:801	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	101	contain	containing	650:659	arg1	medium					643:648	Murashige and Skoog (MS) solid medium	612:648	medium	643:648	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	4	101	contain	containing	650:659	arg2	NAA					694:696	NAA	694:696	NAA	694:696	Adventitious roots were induced most efficiently from leaf explants on Murashige and Skoog (MS) solid medium containing 1.5 mg/L naphthaleneacetic acid (NAA) and 30 g/L sucrose with the highest root induction rate of approximately 92% and 12.9 roots per explant.					
36171502	2	102	theme	root	321:324	arg1	system					334:339	the adventitious root culture system	304:339	the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol	304:408	This study was purposed to establish the adventitious root culture system of A. chinensis for in vitro production of atractylon and β-eudesmol.					
36171502	1	103	theme	bioactive	216:224	arg1	compounds					226:234	its main bioactive compounds	207:234	its main bioactive compounds	207:234	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	1	103	theme	bioactive	216:224	arg1	atractylon					240:249	atractylon	240:249	atractylon	240:249	Atractylodes chinensis is a medicinal plant widely used for the treatment of gastric disorders, and its main bioactive compounds are atractylon and β-eudesmol.					
36171502	5	104	theme	culture	992:998	arg1	8 weeks					981:987	8 weeks	981:987	8 weeks of culture	981:998	During the adventitious root suspension culture, the root biomass and the accumulated content of the target compounds simultaneously increased to reach the maximum values after 8 weeks of culture.					
36171502	3	105	theme	culture	521:527	arg1	efficiency					529:538	the culture efficiency	517:538	the culture efficiency	517:538	The main parameters in the adventitious root induction and suspension cultures were optimized to maximize the culture efficiency.					
36171502	8	106	theme	pharmaceuticals	1619:1633	arg1	production					1592:1601	the industrial production	1577:1601	the industrial production of A. chinensis pharmaceuticals	1577:1633	This work provides a new possibility to have a promising candidate for the industrial production of A. chinensis pharmaceuticals without relying on wild resources or field cultivation.					
35898072	10	0	theme	complex	1776:1782	arg1	environments					1784:1795	different complex environments	1766:1795	different complex environments	1766:1795	This unique combination and the insights gained will improve the detection of biomolecules in different complex environments.					
35898072	8	1	from	discrimination	1396:1409	arg1	solutions					1478:1486	mixed solutions	1472:1486	mixed solutions	1472:1486	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	4	2	theme	plasmonic	609:617	arg1	SEIRA					670:674	SEIRA	670:674	SEIRA	670:674	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	2	theme	plasmonic	609:617	arg1	spectroscopy					656:667	plasmonic surface-enhanced infrared absorption spectroscopy	609:667	plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA)	609:675	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	3	3	theme	sensors	557:563	arg1	limit					484:488	the detection limit	470:488	the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit	470:595	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	3	3	theme	sensors	557:563	arg1	power					520:524	the discriminative power	501:524	the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit	470:595	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	4	4	theme	aqueous	686:692	arg1	solutions					694:702	aqueous solutions	686:702	aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose	686:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	3	5	theme	plasmonic	529:537	arg1	sensors					557:563	plasmonic nanoantenna-based sensors	529:563	plasmonic nanoantenna-based sensors	529:563	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	5	6	theme	plasmonic	906:914	arg1	nanoantennas					916:927	Resonantly tuned plasmonic nanoantennas	889:927	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry	889:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	8	7	theme	reliable	1387:1394	arg1	discrimination					1396:1409	the reliable discrimination	1383:1409	the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously	1383:1549	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	0	8	theme	Analysis	129:136	arg1	Combination					58:68	a Combination	56:68	a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis	56:136	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	8	9	theme	mixed	1472:1476	arg1	solutions					1478:1486	mixed solutions	1472:1486	mixed solutions	1472:1486	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	2	10	theme	aqueous	383:389	arg1	environments					391:402	the complex aqueous environments	371:402	the complex aqueous environments in which various biomolecules are present	371:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	10	11	theme	unique	1677:1682	arg1	combination					1684:1694	This unique combination	1672:1694	This unique combination	1672:1694	This unique combination and the insights gained will improve the detection of biomolecules in different complex environments.					
35898072	7	12	theme	sensor	1191:1196	arg1	performance					1172:1182	The high performance	1163:1182	The high performance of the sensor together with the strength of PCA	1163:1230	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	1	13	theme	ocular	223:228	arg1	fluid					230:234	the ocular fluid	219:234	the ocular fluid	219:234	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	4	14	theme	different	730:738	arg1	saccharides					765:775	up to five different physiologically relevant saccharides	719:775	up to five different physiologically relevant saccharides	719:775	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	14	theme	different	730:738	arg1	disaccharides					854:866	the disaccharides maltose and lactose	850:886	the disaccharides maltose and lactose	850:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	14	theme	different	730:738	arg1	monosaccharides					789:803	the monosaccharides glucose, fructose, and galactose	785:836	the monosaccharides glucose, fructose, and galactose	785:836	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	5	15	theme	cell	950:953	arg1	geometry					955:962	a reflection flow cell geometry	932:962	a reflection flow cell geometry	932:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	4	16	theme	relevant	756:763	arg1	saccharides					765:775	up to five different physiologically relevant saccharides	719:775	up to five different physiologically relevant saccharides	719:775	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	16	theme	relevant	756:763	arg1	disaccharides					854:866	the disaccharides maltose and lactose	850:886	the disaccharides maltose and lactose	850:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	16	theme	relevant	756:763	arg1	monosaccharides					789:803	the monosaccharides glucose, fructose, and galactose	785:836	the monosaccharides glucose, fructose, and galactose	785:836	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	6	17	theme	obtained	1058:1065	arg1	spectra					1067:1073	The obtained spectra	1054:1073	The obtained spectra	1054:1073	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	9	18	from	power	1605:1609	arg1	combination					1646:1656	combination	1646:1656	combination with the PCA	1646:1669	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	0	19	theme	Resonant	73:80	arg1	SEIRA					99:103	Resonant Plasmon-Enhanced SEIRA	73:103	Resonant Plasmon-Enhanced SEIRA	73:103	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	1	20	theme	glucose	175:181	arg1	concentrations					183:196	glucose concentrations	175:196	glucose concentrations	175:196	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	0	21	theme	SEIRA	99:103	arg1	Combination					58:68	a Combination	56:68	a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis	56:136	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	5	22	from	nanoantennas	916:927	arg1	geometry					955:962	a reflection flow cell geometry	932:962	a reflection flow cell geometry	932:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	5	23	theme	vibrational	997:1007	arg1	fingerprints					1009:1020	the specific vibrational fingerprints	984:1020	the specific vibrational fingerprints of the mono- and disaccharides	984:1051	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	0	24	theme	Principal	109:117	arg1	Analysis					129:136	Principal Component Analysis	109:136	Principal Component Analysis	109:136	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	9	25	theme	SEIRA	1624:1628	arg1	spectroscopy					1630:1641	plasmonic SEIRA spectroscopy	1614:1641	plasmonic SEIRA spectroscopy	1614:1641	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	7	26	theme	g/L	1350:1352	arg1	levels					1338:1343	the physiological levels	1320:1343	the physiological levels of 1 g/L	1320:1352	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	4	27	dep	disaccharides	854:866	arg1	disaccharides					854:866	the disaccharides maltose and lactose	850:886	the disaccharides maltose and lactose	850:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	27	dep	disaccharides	854:866	arg1	lactose					880:886	lactose	880:886	lactose	880:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	27	dep	disaccharides	854:866	arg1	maltose					868:874	maltose	868:874	maltose	868:874	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	1	28	theme	patients	293:300	arg1	number					274:279	the increasing number	259:279	the increasing number of diabetes patients	259:300	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	4	29	dep	five	725:728	arg1	to					722:723	to	722:723	to	722:723	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	8	30	theme	concentrations	1429:1442	arg1	discrimination					1396:1409	the reliable discrimination	1383:1409	the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously	1383:1549	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	0	31	theme	Sugar	35:39	arg1	Solutions					41:49	Mixed Sugar Solutions	29:49	Mixed Sugar Solutions	29:49	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	2	32	from	environments	391:402	arg1	present					438:444	present	438:444	present	438:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	7	33	theme	physiological	1324:1336	arg1	levels					1338:1343	the physiological levels	1320:1343	the physiological levels of 1 g/L	1320:1352	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	10	34	theme	different	1766:1774	arg1	environments					1784:1795	different complex environments	1766:1795	different complex environments	1766:1795	This unique combination and the insights gained will improve the detection of biomolecules in different complex environments.					
35898072	4	35	dep	monosaccharides	789:803	arg1	galactose					828:836	galactose	828:836	galactose	828:836	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	35	dep	monosaccharides	789:803	arg1	glucose					805:811	glucose	805:811	glucose	805:811	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	35	dep	monosaccharides	789:803	arg1	monosaccharides					789:803	the monosaccharides glucose, fructose, and galactose	785:836	the monosaccharides glucose, fructose, and galactose	785:836	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	35	dep	monosaccharides	789:803	arg1	fructose					814:821	fructose	814:821	fructose	814:821	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	2	36	theme	low	337:339	arg1	concentrations					341:354	these low concentrations	331:354	these low concentrations	331:354	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	5	37	theme	mono-	1029:1033	arg1	fingerprints					1009:1020	the specific vibrational fingerprints	984:1020	the specific vibrational fingerprints of the mono- and disaccharides	984:1051	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	7	38	theme	solutions	1302:1310	arg1	concentrations					1252:1265	concentrations	1252:1265	concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L	1252:1352	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	8	39	contain	contain	1495:1501	arg2	mono-					1512:1516	five mono-	1507:1516	five mono-	1507:1516	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	8	39	contain	contain	1495:1501	arg1	solutions					1478:1486	mixed solutions	1472:1486	mixed solutions	1472:1486	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	8	39	contain	contain	1495:1501	arg2	disaccharides					1522:1534	disaccharides	1522:1534	disaccharides	1522:1534	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	4	40	theme	surface-enhanced	619:634	arg1	SEIRA					670:674	SEIRA	670:674	SEIRA	670:674	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	40	theme	surface-enhanced	619:634	arg1	spectroscopy					656:667	plasmonic surface-enhanced infrared absorption spectroscopy	609:667	plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA)	609:675	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	3	41	theme	discriminative	505:518	arg1	power					520:524	the discriminative power	501:524	the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit	470:595	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	5	42	theme	disaccharides	1039:1051	arg1	fingerprints					1009:1020	the specific vibrational fingerprints	984:1020	the specific vibrational fingerprints of the mono- and disaccharides	984:1051	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	2	43	from	present	438:444	arg1	environments					391:402	the complex aqueous environments	371:402	the complex aqueous environments in which various biomolecules are present	371:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	4	44	theme	absorption	645:654	arg1	SEIRA					670:674	SEIRA	670:674	SEIRA	670:674	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	44	theme	absorption	645:654	arg1	spectroscopy					656:667	plasmonic surface-enhanced infrared absorption spectroscopy	609:667	plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA)	609:675	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	7	45	theme	aqueous	1270:1276	arg1	solutions					1302:1310	aqueous mono- and disaccharides solutions	1270:1310	aqueous mono- and disaccharides solutions	1270:1310	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	3	46	theme	nanoantenna-based	539:555	arg1	sensors					557:563	plasmonic nanoantenna-based sensors	529:563	plasmonic nanoantenna-based sensors	529:563	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	1	47	theme	increasing	263:272	arg1	number					274:279	the increasing number	259:279	the increasing number of diabetes patients	259:300	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	9	48	with	combination	1646:1656	arg1	PCA					1667:1669	the PCA	1663:1669	the PCA	1663:1669	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	1	49	theme	human	201:205	arg1	blood					207:211	human blood	201:211	human blood	201:211	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	1	50	theme	concentrations	183:196	arg1	quantification					157:170	quantification	157:170	quantification	157:170	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	1	50	theme	concentrations	183:196	arg1	detection					143:151	detection	143:151	detection	143:151	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	3	51	theme	physiological	577:589	arg1	limit					591:595	the physiological limit	573:595	the physiological limit	573:595	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	5	52	theme	tuned	900:904	arg1	nanoantennas					916:927	Resonantly tuned plasmonic nanoantennas	889:927	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry	889:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	2	53	theme	reliable	305:312	arg1	determination					314:326	A reliable determination	303:326	A reliable determination of these low concentrations	303:354	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	2	54	theme	complex	375:381	arg1	environments					391:402	the complex aqueous environments	371:402	the complex aqueous environments in which various biomolecules are present	371:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	5	55	theme	reflection	934:943	arg1	geometry					955:962	a reflection flow cell geometry	932:962	a reflection flow cell geometry	932:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	5	56	theme	flow	945:948	arg1	geometry					955:962	a reflection flow cell geometry	932:962	a reflection flow cell geometry	932:962	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	9	57	theme	excellent	1580:1588	arg1	power					1605:1609	the excellent discriminative power	1576:1609	the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA	1576:1669	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	3	58	theme	detection	474:482	arg1	limit					484:488	the detection limit	470:488	the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit	470:595	In this study, we push the detection limit as well as the discriminative power of plasmonic nanoantenna-based sensors towards the physiological limit.					
35898072	4	59	theme	mixtures	707:714	arg1	solutions					694:702	aqueous solutions	686:702	aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose	686:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	0	60	theme	Plasmon-Enhanced	82:97	arg1	SEIRA					99:103	Resonant Plasmon-Enhanced SEIRA	73:103	Resonant Plasmon-Enhanced SEIRA	73:103	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	10	61	theme	biomolecules	1750:1761	arg1	detection					1737:1745	the detection	1733:1745	the detection of biomolecules in different complex environments	1733:1795	This unique combination and the insights gained will improve the detection of biomolecules in different complex environments.					
35898072	7	62	theme	PCA	1228:1230	arg1	strength					1216:1223	the strength	1212:1223	the strength of PCA	1212:1230	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	5	63	theme	specific	988:995	arg1	fingerprints					1009:1020	the specific vibrational fingerprints	984:1020	the specific vibrational fingerprints of the mono- and disaccharides	984:1051	Resonantly tuned plasmonic nanoantennas in a reflection flow cell geometry allow us to enhance the specific vibrational fingerprints of the mono- and disaccharides.					
35898072	9	64	theme	discriminative	1590:1603	arg1	power					1605:1609	the excellent discriminative power	1576:1609	the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA	1576:1669	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	1	65	dep	detection	143:151	arg1	The					139:141	The	139:141	The	139:141	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	6	66	theme	learning	1143:1150	arg1	algorithm					1152:1160	a machine learning algorithm	1133:1160	a machine learning algorithm	1133:1160	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	0	67	theme	Component	119:127	arg1	Analysis					129:136	Principal Component Analysis	109:136	Principal Component Analysis	109:136	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	1	68	from	quantification	157:170	arg1	fluid					230:234	the ocular fluid	219:234	the ocular fluid	219:234	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	1	68	from	quantification	157:170	arg1	blood					207:211	human blood	201:211	human blood	201:211	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	1	69	from	detection	143:151	arg1	fluid					230:234	the ocular fluid	219:234	the ocular fluid	219:234	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	1	69	from	detection	143:151	arg1	blood					207:211	human blood	201:211	human blood	201:211	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	9	70	theme	plasmonic	1614:1622	arg1	spectroscopy					1630:1641	plasmonic SEIRA spectroscopy	1614:1641	plasmonic SEIRA spectroscopy	1614:1641	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	4	71	theme	saccharides	765:775	arg1	mixtures					707:714	mixtures	707:714	mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose	707:886	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	2	72	located	present	438:444	arg2	biomolecules					421:432	various biomolecules	413:432	various biomolecules	413:432	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	2	72	located	present	438:444	arg1	environments					391:402	the complex aqueous environments	371:402	the complex aqueous environments in which various biomolecules are present	371:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	0	73	theme	Mixed	29:33	arg1	Solutions					41:49	Mixed Sugar Solutions	29:49	Mixed Sugar Solutions	29:49	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	1	74	theme	diabetes	284:291	arg1	patients					293:300	diabetes patients	284:300	diabetes patients	284:300	The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.					
35898072	9	75	theme	spectroscopy	1630:1641	arg1	power					1605:1609	the excellent discriminative power	1576:1609	the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA	1576:1669	These results underline the excellent discriminative power of plasmonic SEIRA spectroscopy in combination with the PCA.					
35898072	6	76	theme	principal	1092:1100	arg1	analysis					1112:1119	principal component analysis	1092:1119	principal component analysis (PCA)	1092:1125	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	6	76	theme	principal	1092:1100	arg1	PCA					1122:1124	PCA	1122:1124	PCA	1122:1124	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	6	77	theme	machine	1135:1141	arg1	algorithm					1152:1160	a machine learning algorithm	1133:1160	a machine learning algorithm	1133:1160	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	0	78	theme	Solutions	41:49	arg1	Concentrations					11:24	Concentrations	11:24	Concentrations of Mixed Sugar Solutions	11:49	Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.					
35898072	2	79	attach	present	438:444	arg2	biomolecules					421:432	various biomolecules	413:432	various biomolecules	413:432	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	2	79	attach	present	438:444	arg1	environments					391:402	the complex aqueous environments	371:402	the complex aqueous environments in which various biomolecules are present	371:444	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	8	80	theme	saccharide	1418:1427	arg1	concentrations					1429:1442	the saccharide concentrations	1414:1442	the saccharide concentrations	1414:1442	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
35898072	2	81	theme	various	413:419	arg1	biomolecules					421:432	various biomolecules	413:432	various biomolecules	413:432	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	7	82	theme	high	1167:1170	arg1	performance					1172:1182	The high performance	1163:1182	The high performance of the sensor together with the strength of PCA	1163:1230	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	7	83	theme	down	1312:1315	arg1	concentrations					1252:1265	concentrations	1252:1265	concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L	1252:1352	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	6	84	theme	component	1102:1110	arg1	analysis					1112:1119	principal component analysis	1092:1119	principal component analysis (PCA)	1092:1125	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	6	84	theme	component	1102:1110	arg1	PCA					1122:1124	PCA	1122:1124	PCA	1122:1124	The obtained spectra are analyzed via principal component analysis (PCA) using a machine learning algorithm.					
35898072	2	85	theme	concentrations	341:354	arg1	determination					314:326	A reliable determination	303:326	A reliable determination of these low concentrations	303:354	A reliable determination of these low concentrations is hindered by the complex aqueous environments in which various biomolecules are present.					
35898072	7	86	theme	disaccharides	1288:1300	arg1	solutions					1302:1310	aqueous mono- and disaccharides solutions	1270:1310	aqueous mono- and disaccharides solutions	1270:1310	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	10	87	from	detection	1737:1745	arg1	environments					1784:1795	different complex environments	1766:1795	different complex environments	1766:1795	This unique combination and the insights gained will improve the detection of biomolecules in different complex environments.					
35898072	4	88	theme	infrared	636:643	arg1	SEIRA					670:674	SEIRA	670:674	SEIRA	670:674	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	4	88	theme	infrared	636:643	arg1	spectroscopy					656:667	plasmonic surface-enhanced infrared absorption spectroscopy	609:667	plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA)	609:675	We utilize plasmonic surface-enhanced infrared absorption spectroscopy (SEIRA) to study aqueous solutions of mixtures of up to five different physiologically relevant saccharides, namely the monosaccharides glucose, fructose, and galactose, as well as the disaccharides maltose and lactose.					
35898072	7	89	theme	mono-	1278:1282	arg1	solutions					1302:1310	aqueous mono- and disaccharides solutions	1270:1310	aqueous mono- and disaccharides solutions	1270:1310	The high performance of the sensor together with the strength of PCA allows us to detect concentrations of aqueous mono- and disaccharides solutions down to the physiological levels of 1 g/L.					
35898072	8	90	theme	compositions	1456:1467	arg1	discrimination					1396:1409	the reliable discrimination	1383:1409	the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously	1383:1549	Furthermore, we demonstrate the reliable discrimination of the saccharide concentrations, as well as compositions in mixed solutions, which contain all five mono- and disaccharides simultaneously.					
36555821	6	0	dep	In	1092:1093	arg1	vitro					1095:1099	vitro	1095:1099	vitro	1095:1099	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	4	1	theme	phosphate-BC	592:603	arg1	membranes					614:622	Calcium phosphate-BC oxidized membranes	584:622	Calcium phosphate-BC oxidized membranes	584:622	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	9	2	theme	calcium	1490:1496	arg1	phosphate					1498:1506	calcium phosphate	1490:1506	calcium phosphate	1490:1506	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	1	3	theme	Bacterial	91:99	arg1	cellulose					101:109	Bacterial cellulose	91:109	Bacterial cellulose (BC)	91:114	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	3	theme	Bacterial	91:99	arg1	biopolymer					138:147	a unique microbial biopolymer	119:147	a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering	119:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	3	theme	Bacterial	91:99	arg1	BC					112:113	BC	112:113	BC	112:113	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	4	4	theme	ultrasonic	691:700	arg1	irradiation					702:712	ultrasonic irradiation	691:712	ultrasonic irradiation	691:712	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	2	5	theme	present	260:266	arg1	study					268:272	The present study	256:272	The present study	256:272	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	1	6	theme	significant	171:181	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	6	theme	significant	171:181	arg1	applications					183:194	significant applications	171:194	significant applications	171:194	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	7	theme	infrared	922:929	arg1	spectroscopy					942:953	infrared (ATR-FTIR) spectroscopy	922:953	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	7	theme	infrared	922:929	arg1	GI-XRD					992:997	GI-XRD	992:997	GI-XRD	992:997	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	8	theme	ATR-FTIR	932:939	arg1	spectroscopy					942:953	infrared (ATR-FTIR) spectroscopy	922:953	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	8	theme	ATR-FTIR	932:939	arg1	GI-XRD					992:997	GI-XRD	992:997	GI-XRD	992:997	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	1	9	from	applications	183:194	arg1	field					214:218	the biomedical field	199:218	the biomedical field	199:218	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	10	theme	unique	121:126	arg1	biopolymer					138:147	a unique microbial biopolymer	119:147	a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering	119:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	10	theme	unique	121:126	arg1	cellulose					101:109	Bacterial cellulose	91:109	Bacterial cellulose (BC)	91:114	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	6	11	theme	In	1092:1093	arg1	studies					1106:1112	In vitro cell studies	1092:1112	In vitro cell studies	1092:1112	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	0	12	theme	Bone	65:68	arg1	Regeneration					77:88	Bone Tissue Regeneration	65:88	Bone Tissue Regeneration	65:88	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	5	13	theme	reflectance-Fourier	892:910	arg1	spectroscopy					942:953	infrared (ATR-FTIR) spectroscopy	922:953	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	13	theme	reflectance-Fourier	892:910	arg1	GI-XRD					992:997	GI-XRD	992:997	GI-XRD	992:997	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	8	14	theme	cell	1417:1420	arg1	adhesion					1422:1429	cell adhesion	1417:1429	cell adhesion	1417:1429	In vitro cell studies have revealed that both hybrid composites favor cell adhesion to the surface.					
36555821	7	15	theme	DABC	1306:1309	arg1	composites					1318:1327	DABC hybrid composites	1306:1327	DABC hybrid composites	1306:1327	The results showed an increase in porosity and biodegradability for DABC hybrid composites compared with BC.					
36555821	5	16	theme	scanning	789:796	arg1	SEM					819:821	SEM	819:821	SEM	819:821	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	16	theme	scanning	789:796	arg1	microscopy					807:816	scanning electron microscopy	789:816	scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis	789:1089	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	1	17	with	biopolymer	138:147	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	17	with	biopolymer	138:147	arg1	number					161:166	a huge number	154:166	a huge number of significant applications in the biomedical field, including bone tissue engineering	154:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	18	theme	13C	1052:1054	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	18	theme	13C	1052:1054	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	19	theme	13C	1013:1015	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	19	theme	13C	1013:1015	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	2	20	theme	bone	399:402	arg1	engineering					411:421	bone tissue engineering	399:421	bone tissue engineering	399:421	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	8	21	dep	In	1347:1348	arg1	vitro					1350:1354	vitro	1350:1354	vitro	1350:1354	In vitro cell studies have revealed that both hybrid composites favor cell adhesion to the surface.					
36555821	7	22	from	increase	1260:1267	arg1	biodegradability					1285:1300	biodegradability	1285:1300	biodegradability	1285:1300	The results showed an increase in porosity and biodegradability for DABC hybrid composites compared with BC.					
36555821	7	22	from	increase	1260:1267	arg1	porosity					1272:1279	porosity	1272:1279	porosity	1272:1279	The results showed an increase in porosity and biodegradability for DABC hybrid composites compared with BC.					
36555821	0	23	theme	Tissue	70:75	arg1	Regeneration					77:88	Bone Tissue Regeneration	65:88	Bone Tissue Regeneration	65:88	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	3	24	theme	precursor	427:435	arg1	membranes					437:445	BC precursor membranes	424:445	BC precursor membranes	424:445	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	0	25	theme	Bacterial	0:8	arg1	Composites					27:36	Bacterial Cellulose Hybrid Composites	0:36	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration	0:88	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	5	26	theme	magnetic	1025:1032	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	26	theme	magnetic	1025:1032	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	3	27	theme	culture	471:477	arg1	fermentation					479:490	static culture fermentation	464:490	static culture fermentation	464:490	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	0	28	theme	Hybrid	20:25	arg1	Composites					27:36	Bacterial Cellulose Hybrid Composites	0:36	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration	0:88	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	2	29	with	composites	320:329	arg1	phosphate					344:352	calcium phosphate	336:352	calcium phosphate as biocompatible and bioactive membranes	336:393	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	1	30	theme	microbial	128:136	arg1	biopolymer					138:147	a unique microbial biopolymer	119:147	a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering	119:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	30	theme	microbial	128:136	arg1	cellulose					101:109	Bacterial cellulose	91:109	Bacterial cellulose (BC)	91:114	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	31	theme	energy-dispersive	837:853	arg1	spectroscopy					861:872	energy-dispersive X-ray spectroscopy	837:872	energy-dispersive X-ray spectroscopy	837:872	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	6	32	theme	cell	1101:1104	arg1	studies					1106:1112	In vitro cell studies	1092:1112	In vitro cell studies	1092:1112	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	2	33	theme	calcium	336:342	arg1	phosphate					344:352	calcium phosphate	336:352	calcium phosphate as biocompatible and bioactive membranes	336:393	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	9	34	theme	new	1451:1453	arg1	BC					1455:1456	The new BC and DABC hybrid composites	1447:1483	BC	1455:1456	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	6	35	theme	cell	1205:1208	arg1	adhesion					1210:1217	cell adhesion	1205:1217	cell adhesion	1205:1217	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	3	36	theme	2,3-dialdehyde	541:554	arg1	DABC					577:580	DABC	577:580	DABC	577:580	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	3	36	theme	2,3-dialdehyde	541:554	arg1	cellulose					566:574	2,3-dialdehyde bacterial cellulose	541:574	2,3-dialdehyde bacterial cellulose (DABC)	541:581	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	6	37	theme	characteristics	1186:1200	arg1	influence					1150:1158	the influence	1146:1158	the influence of modified morphological characteristics on cell adhesion and proliferation	1146:1235	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	2	38	theme	tissue	404:409	arg1	engineering					411:421	bone tissue engineering	399:421	bone tissue engineering	399:421	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	6	39	from	influence	1150:1158	arg1	proliferation					1223:1235	proliferation	1223:1235	proliferation	1223:1235	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	6	39	from	influence	1150:1158	arg1	adhesion					1210:1217	cell adhesion	1205:1217	cell adhesion	1205:1217	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	9	40	theme	hybrid	1467:1472	arg1	composites					1474:1483	The new BC and DABC hybrid composites	1447:1483	composites	1474:1483	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	5	41	theme	thermal	1074:1080	arg1	analysis					1082:1089	complex thermal analysis	1066:1089	complex thermal analysis	1066:1089	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	6	42	theme	modified	1163:1170	arg1	characteristics					1186:1200	modified morphological characteristics	1163:1200	modified morphological characteristics	1163:1200	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	1	43	theme	tissue	236:241	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	4	44	theme	Calcium	584:590	arg1	phosphate-BC					592:603	Calcium phosphate-BC	584:603	Calcium phosphate-BC oxidized membranes	584:622	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	9	45	with	BC	1455:1456	arg1	phosphate					1498:1506	calcium phosphate	1490:1506	calcium phosphate	1490:1506	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	3	46	theme	bacterial	556:564	arg1	DABC					577:580	DABC	577:580	DABC	577:580	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	3	46	theme	bacterial	556:564	arg1	cellulose					566:574	2,3-dialdehyde bacterial cellulose	541:574	2,3-dialdehyde bacterial cellulose (DABC)	541:581	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	4	47	theme	oxidized	605:612	arg1	membranes					614:622	Calcium phosphate-BC oxidized membranes	584:622	Calcium phosphate-BC oxidized membranes	584:622	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	9	48	theme	promising	1528:1536	arg1	materials					1538:1546	promising materials	1528:1546	promising materials for bone tissue regeneration	1528:1575	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	1	49	theme	huge	156:159	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	49	theme	huge	156:159	arg1	number					161:166	a huge number	154:166	a huge number of significant applications in the biomedical field, including bone tissue engineering	154:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	2	50	theme	BC	310:311	arg1	composites					320:329	BC hybrid composites	310:329	BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering	310:421	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	5	51	theme	grazing	955:961	arg1	diffraction					979:989	grazing incidence X-ray diffraction	955:989	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	1	52	theme	applications	183:194	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	52	theme	applications	183:194	arg1	number					161:166	a huge number	154:166	a huge number of significant applications in the biomedical field, including bone tissue engineering	154:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	8	53	theme	In	1347:1348	arg1	studies					1361:1367	In vitro cell studies	1347:1367	In vitro cell studies	1347:1367	In vitro cell studies have revealed that both hybrid composites favor cell adhesion to the surface.					
36555821	5	54	theme	physicochemical	756:770	arg1	properties					772:781	their physicochemical properties	750:781	their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis	750:1089	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	4	55	from	immersion	652:660	arg1	solutions					675:683	precursor solutions	665:683	precursor solutions	665:683	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	9	56	theme	tissue	1557:1562	arg1	regeneration					1564:1575	bone tissue regeneration	1552:1575	bone tissue regeneration	1552:1575	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	4	57	theme	precursor	665:673	arg1	solutions					675:683	precursor solutions	665:683	precursor solutions	665:683	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	1	58	from	field	214:218	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	1	58	from	field	214:218	arg1	number					161:166	a huge number	154:166	a huge number of significant applications in the biomedical field, including bone tissue engineering	154:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	59	theme	solid-state	1001:1011	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	59	theme	solid-state	1001:1011	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	60	theme	incidence	963:971	arg1	diffraction					979:989	grazing incidence X-ray diffraction	955:989	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	7	61	theme	hybrid	1311:1316	arg1	composites					1318:1327	DABC hybrid composites	1306:1327	DABC hybrid composites	1306:1327	The results showed an increase in porosity and biodegradability for DABC hybrid composites compared with BC.					
36555821	5	62	theme	X-ray	973:977	arg1	diffraction					979:989	grazing incidence X-ray diffraction	955:989	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	8	63	theme	hybrid	1393:1398	arg1	composites					1400:1409	both hybrid composites	1388:1409	both hybrid composites	1388:1409	In vitro cell studies have revealed that both hybrid composites favor cell adhesion to the surface.					
36555821	1	64	from	number	161:166	arg1	field					214:218	the biomedical field	199:218	the biomedical field	199:218	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	65	theme	CP/MAS	1045:1050	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	65	theme	CP/MAS	1045:1050	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	66	theme	electron	798:805	arg1	SEM					819:821	SEM	819:821	SEM	819:821	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	66	theme	electron	798:805	arg1	microscopy					807:816	scanning electron microscopy	789:816	scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis	789:1089	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	9	67	theme	bone	1552:1555	arg1	regeneration					1564:1575	bone tissue regeneration	1552:1575	bone tissue regeneration	1552:1575	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	0	68	theme	Cellulose	10:18	arg1	Composites					27:36	Bacterial Cellulose Hybrid Composites	0:36	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration	0:88	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	5	69	theme	nuclear	1017:1023	arg1	resonance					1034:1042	solid-state 13C nuclear magnetic resonance	1001:1042	solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR)	1001:1059	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	69	theme	nuclear	1017:1023	arg1	NMR					1056:1058	CP/MAS 13C NMR	1045:1058	CP/MAS 13C NMR	1045:1058	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	2	70	theme	bioactive	375:383	arg1	membranes					385:393	biocompatible and bioactive membranes	357:393	membranes	385:393	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	5	71	theme	total	886:890	arg1	spectroscopy					942:953	infrared (ATR-FTIR) spectroscopy	922:953	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	71	theme	total	886:890	arg1	GI-XRD					992:997	GI-XRD	992:997	GI-XRD	992:997	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	72	theme	attenuated	875:884	arg1	spectroscopy					942:953	infrared (ATR-FTIR) spectroscopy	922:953	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	72	theme	attenuated	875:884	arg1	GI-XRD					992:997	GI-XRD	992:997	GI-XRD	992:997	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	9	73	with	composites	1474:1483	arg1	phosphate					1498:1506	calcium phosphate	1490:1506	calcium phosphate	1490:1506	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	0	74	theme	Calcium	43:49	arg1	Phosphate					51:59	Calcium Phosphate	43:59	Calcium Phosphate	43:59	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	3	75	theme	BC	424:425	arg1	membranes					437:445	BC precursor membranes	424:445	BC precursor membranes	424:445	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	0	76	with	Composites	27:36	arg1	Phosphate					51:59	Calcium Phosphate	43:59	Calcium Phosphate	43:59	Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration.					
36555821	3	77	theme	static	464:469	arg1	fermentation					479:490	static culture fermentation	464:490	static culture fermentation	464:490	BC precursor membranes were obtained in static culture fermentation, and after purification, were oxidized to obtain 2,3-dialdehyde bacterial cellulose (DABC).					
36555821	5	78	theme	X-ray	855:859	arg1	spectroscopy					861:872	energy-dispersive X-ray spectroscopy	837:872	energy-dispersive X-ray spectroscopy	837:872	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	79	dep	spectroscopy	942:953	arg1	transform					912:920	transform	912:920	transform	912:920	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	5	79	dep	spectroscopy	942:953	arg1	diffraction					979:989	grazing incidence X-ray diffraction	955:989	attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD)	875:998	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	8	80	theme	cell	1356:1359	arg1	studies					1361:1367	In vitro cell studies	1347:1367	In vitro cell studies	1347:1367	In vitro cell studies have revealed that both hybrid composites favor cell adhesion to the surface.					
36555821	2	81	theme	hybrid	313:318	arg1	composites					320:329	BC hybrid composites	310:329	BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering	310:421	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	9	82	theme	DABC	1462:1465	arg1	composites					1474:1483	The new BC and DABC hybrid composites	1447:1483	composites	1474:1483	The new BC and DABC hybrid composites with calcium phosphate could be considered promising materials for bone tissue regeneration.					
36555821	1	83	theme	biomedical	203:212	arg1	field					214:218	the biomedical field	199:218	the biomedical field	199:218	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
36555821	5	84	theme	complex	1066:1072	arg1	analysis					1082:1089	complex thermal analysis	1066:1089	complex thermal analysis	1066:1089	The samples were characterized for their physicochemical properties using scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy grazing incidence X-ray diffraction (GI-XRD), solid-state 13C nuclear magnetic resonance (CP/MAS 13C NMR), and complex thermal analysis.					
36555821	6	85	theme	morphological	1172:1184	arg1	characteristics					1186:1200	modified morphological characteristics	1163:1200	modified morphological characteristics	1163:1200	In vitro cell studies were also performed to evaluate the influence of modified morphological characteristics on cell adhesion and proliferation.					
36555821	4	86	theme	successive	641:650	arg1	immersion					652:660	successive immersion	641:660	successive immersion in precursor solutions under ultrasonic irradiation	641:712	Calcium phosphate-BC oxidized membranes were produced by successive immersion in precursor solutions under ultrasonic irradiation.					
36555821	2	87	theme	biocompatible	357:369	arg1	membranes					385:393	biocompatible and bioactive membranes	357:393	membranes	385:393	The present study proposes to obtain and characterize BC hybrid composites with calcium phosphate as biocompatible and bioactive membranes for bone tissue engineering.					
36555821	1	88	theme	bone	231:234	arg1	engineering					243:253	bone tissue engineering	231:253	bone tissue engineering	231:253	Bacterial cellulose (BC) is a unique microbial biopolymer with a huge number of significant applications in the biomedical field, including bone tissue engineering.					
35131355	0	0	theme	Tenofovir	95:103	arg1	release					84:90	intravaginal pH-responsive release	57:90	intravaginal pH-responsive release of Tenofovir	57:103	Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.					
35131355	5	1	theme	drug	739:742	arg1	release					744:750	drug release	739:750	drug release	739:750	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	7	2	theme	excellent	1153:1161	arg1	properties					1174:1183	their excellent mechanical properties	1147:1183	their excellent mechanical properties	1147:1183	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	5	3	theme	vaginal	759:765	arg1	medium					767:772	the vaginal medium	755:772	the vaginal medium	755:772	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	2	4	theme	antiretroviral	294:307	arg1	drugs					309:313	antiretroviral drugs	294:313	antiretroviral drugs	294:313	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	3	5	theme	Tenofovir-loaded	368:383	arg1	films					385:389	Tenofovir-loaded films	368:389	Tenofovir-loaded films	368:389	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	6	6	theme	Tenofovir	870:878	arg1	release					880:886	Tenofovir release	870:886	Tenofovir release for days	870:895	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	7	7	theme	plasticizers	1043:1054	arg1	content					1022:1028	the highest tested content	1003:1028	the highest tested content of EL100 and plasticizers	1003:1054	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	8	theme	vaginal	1086:1092	arg1	microbicides					1094:1105	vaginal microbicides	1086:1105	vaginal microbicides	1086:1105	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	6	9	from	hours	944:948	arg1	presence					957:964	the presence	953:964	the presence of seminal fluid	953:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	2	10	theme	vaginal	268:274	arg1	administration					276:289	vaginal administration	268:289	vaginal administration of antiretroviral drugs	268:313	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	7	11	theme	pH-responsive	1294:1306	arg1	release					1308:1314	their pH-responsive release	1288:1314	their pH-responsive release of Tenofovir	1288:1327	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	12	theme	mechanical	1163:1172	arg1	properties					1174:1183	their excellent mechanical properties	1147:1183	their excellent mechanical properties	1147:1183	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	13	theme	EL100	1033:1037	arg1	content					1022:1028	the highest tested content	1003:1028	the highest tested content of EL100 and plasticizers	1003:1054	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	14	theme	comfortable	1205:1215	arg1	posology					1217:1224	more comfortable posology	1200:1224	more comfortable posology	1200:1224	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	1	15	theme	prevention	181:190	arg1	tools					192:196	prevention tools	181:196	prevention tools	181:196	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	6	16	theme	few	940:942	arg1	hours					944:948	a few hours	938:948	a few hours in the presence of seminal fluid	938:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	3	17	theme	films	385:389	arg1	batches					357:363	Six batches	353:363	Six batches of Tenofovir-loaded films	353:389	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	2	18	theme	Different	221:229	arg1	forms					238:242	Different dosage forms	221:242	Different dosage forms - including films - for vaginal administration of antiretroviral drugs	221:313	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	2	18	theme	Different	221:229	arg1	films					256:260	films	256:260	films	256:260	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	1	19	theme	high	110:113	arg1	rate					115:118	The high rate	106:118	The high rate of HIV new infections	106:140	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	3	20	theme	triethyl	464:471	arg1	citrate					473:479	triethyl citrate	464:479	triethyl citrate	464:479	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	3	21	contain	containing	453:462	arg2	citrate					473:479	triethyl citrate	464:479	triethyl citrate	464:479	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	3	21	contain	containing	453:462	arg1	chitosan					443:450	chitosan	443:450	chitosan	443:450	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	3	21	contain	containing	453:462	arg2	glycerol					485:492	glycerol	485:492	glycerol	485:492	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	2	22	theme	drugs	309:313	arg1	administration					276:289	vaginal administration	268:289	vaginal administration of antiretroviral drugs	268:313	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	1	23	theme	necessary	204:212	arg1	today					214:218	still necessary today	198:218	still necessary today	198:218	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	4	24	theme	upper	549:553	arg1	layers					536:541	two layers	532:541	two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan	532:618	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	4	24	theme	upper	549:553	arg1	layer					555:559	the upper layer	545:559	the upper layer mainly attributed to EL100	545:586	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	6	25	theme	structuring	838:848	arg1	layer					822:826	The EL100-based layer	806:826	The EL100-based layer	806:826	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	6	25	theme	structuring	838:848	arg1	agent					850:854	a structuring agent	836:854	a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid	836:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	0	26	theme	bilayer	39:45	arg1	films					47:51	thin bilayer films	34:51	thin bilayer films	34:51	Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.					
35131355	7	27	theme	tested	1015:1020	arg1	content					1022:1028	the highest tested content	1003:1028	the highest tested content of EL100 and plasticizers	1003:1054	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	5	28	theme	mechanical	700:709	arg1	properties					711:720	the mechanical properties	696:720	the mechanical properties	696:720	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	0	29	theme	thin	34:37	arg1	films					47:51	thin bilayer films	34:51	thin bilayer films	34:51	Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.					
35131355	0	30	theme	intravaginal	57:68	arg1	release					84:90	intravaginal pH-responsive release	57:90	intravaginal pH-responsive release of Tenofovir	57:103	Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.					
35131355	7	31	dep	tested	1015:1020	arg1	highest					1007:1013	highest	1007:1013	highest	1007:1013	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	2	32	theme	dosage	231:236	arg1	forms					238:242	Different dosage forms	221:242	Different dosage forms - including films - for vaginal administration of antiretroviral drugs	221:313	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	2	32	theme	dosage	231:236	arg1	films					256:260	films	256:260	films	256:260	Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for this purpose.					
35131355	7	33	theme	enhanced	1230:1237	arg1	protection					1239:1248	enhanced protection	1230:1248	enhanced protection against HIV	1230:1260	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	3	34	theme	Eudragit®	416:424	arg1	EL100					432:436	EL100	432:436	EL100	432:436	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	3	34	theme	Eudragit®	416:424	arg1	L100					426:429	Eudragit® L100	416:429	Eudragit® L100 (EL100)	416:437	Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate and glycerol.					
35131355	5	35	theme	higher	646:651	arg1	content					653:659	A higher content	644:659	A higher content in EL100 and plasticizers	644:685	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	1	36	theme	AIDS-related	146:157	arg1	deaths					159:164	AIDS-related deaths	146:164	AIDS-related deaths	146:164	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	1	37	theme	HIV	123:125	arg1	infections					131:140	HIV new infections	123:140	HIV new infections	123:140	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	6	38	theme	vaginal	904:910	arg1	medium					912:917	the vaginal medium	900:917	the vaginal medium	900:917	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	7	39	theme	Bilayer	984:990	arg1	films					992:996	Bilayer films	984:996	Bilayer films with the highest tested content of EL100 and plasticizers	984:1054	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	39	theme	Bilayer	984:990	arg1	suitable					1074:1081	suitable	1074:1081	suitable	1074:1081	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	7	40	theme	Tenofovir	1319:1327	arg1	release					1308:1314	their pH-responsive release	1288:1314	their pH-responsive release of Tenofovir	1288:1327	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	1	41	theme	new	127:129	arg1	infections					131:140	HIV new infections	123:140	HIV new infections	123:140	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	5	42	from	content	653:659	arg1	plasticizers					674:685	plasticizers	674:685	plasticizers	674:685	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	5	42	from	content	653:659	arg1	EL100					664:668	EL100	664:668	EL100	664:668	A higher content in EL100 and plasticizers improves the mechanical properties and control over drug release in the vaginal medium without affecting mucoadhesion.					
35131355	6	43	theme	EL100-based	810:820	arg1	layer					822:826	The EL100-based layer	806:826	The EL100-based layer	806:826	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	6	43	theme	EL100-based	810:820	arg1	agent					850:854	a structuring agent	836:854	a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid	836:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	1	44	theme	infections	131:140	arg1	deaths					159:164	AIDS-related deaths	146:164	AIDS-related deaths	146:164	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	1	44	theme	infections	131:140	arg1	rate					115:118	The high rate	106:118	The high rate of HIV new infections	106:140	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	6	45	theme	fluid	977:981	arg1	presence					957:964	the presence	953:964	the presence of seminal fluid	953:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	7	46	with	films	992:996	arg1	content					1022:1028	the highest tested content	1003:1028	the highest tested content of EL100 and plasticizers	1003:1054	Bilayer films with the highest tested content of EL100 and plasticizers would be the most suitable as vaginal microbicides as they are easier to administer due to their excellent mechanical properties and they offer more comfortable posology and enhanced protection against HIV during intercourse due to their pH-responsive release of Tenofovir.					
35131355	6	47	theme	seminal	969:975	arg1	fluid					977:981	seminal fluid	969:981	seminal fluid	969:981	The EL100-based layer acts as a structuring agent that controls Tenofovir release for days in the vaginal medium while it occurs in a few hours in the presence of seminal fluid.					
35131355	0	48	theme	pH-responsive	70:82	arg1	release					84:90	intravaginal pH-responsive release	57:90	intravaginal pH-responsive release of Tenofovir	57:103	Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.					
35131355	4	49	dep	layers	536:541	arg1	layers					536:541	two layers	532:541	two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan	532:618	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	4	49	dep	layers	536:541	arg1	layer					555:559	the upper layer	545:559	the upper layer mainly attributed to EL100	545:586	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	4	49	dep	layers	536:541	arg1	layer					602:606	the lower layer	592:606	the lower layer to chitosan	592:618	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	1	50	dep	rate	115:118	arg1	year					171:174	each year	166:174	each year	166:174	The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today.					
35131355	4	51	theme	lower	596:600	arg1	layers					536:541	two layers	532:541	two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan	532:618	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
35131355	4	51	theme	lower	596:600	arg1	layer					602:606	the lower layer	592:606	the lower layer to chitosan	592:618	In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - were revealed by SEM.					
34315365	0	0	theme	Composite	99:107	arg1	Design					109:114	Central Composite Design	91:114	Central Composite Design	91:114	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	6	1	theme	zeta	988:991	arg1	potential					993:1001	a zeta potential	986:1001	a zeta potential of about 11 mV	986:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	3	2	theme	desired	512:518	arg1	results					520:526	the desired results	508:526	the desired results	508:526	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	12	3	theme	release	1479:1485	arg1	study					1487:1491	The ex-vivo release study	1467:1491	The ex-vivo release study	1467:1491	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	0	4	theme	Central	91:97	arg1	Design					109:114	Central Composite Design	91:114	Central Composite Design	91:114	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	8	5	theme	scanning	1126:1133	arg1	microscopy					1144:1153	scanning electron microscopy	1126:1153	scanning electron microscopy	1126:1153	The surface morphology of NPs was observed by scanning electron microscopy.					
34315365	1	6	theme	Due	177:179	arg1	BACKGROUND					166:175	BACKGROUND	166:175	BACKGROUND Due to the increased resistance against existing antibiotics	166:236	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	1	7	theme	new	273:275	arg1	ways					293:296	new and alternative ways	273:296	new and alternative ways to control infections induced by resistant pathogens	273:349	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	6	8	theme	optimized	879:887	arg1	NPs					889:891	The optimized NPs	875:891	The optimized NPs	875:891	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	7	9	theme	NPs	1075:1077	arg1	size					1067:1070	the size	1063:1070	the size of NPs	1063:1077	The scanning tunneling microscope confirmed the size of NPs.					
34315365	11	10	theme	various	1416:1422	arg1	types					1424:1428	various types	1416:1428	various types of bacteria	1416:1440	The potency of CEF in NPs against various types of bacteria was hopefully efficient.					
34315365	12	11	from	penetration	1513:1523	arg1	intestine					1545:1553	the rat intestine	1537:1553	the rat intestine	1537:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	10	12	theme	NPs	1268:1270	arg1	acceptable					1293:1302	acceptable	1293:1302	acceptable	1293:1302	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	10	12	theme	NPs	1268:1270	arg1	rate					1260:1263	The dissolution rate	1244:1263	The dissolution rate of NPs in aqueous media	1244:1287	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	1	13	theme	alternative	281:291	arg1	ways					293:296	new and alternative ways	273:296	new and alternative ways to control infections induced by resistant pathogens	273:349	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	8	14	theme	electron	1135:1142	arg1	microscopy					1144:1153	scanning electron microscopy	1126:1153	scanning electron microscopy	1126:1153	The surface morphology of NPs was observed by scanning electron microscopy.					
34315365	6	15	theme	mV	1015:1016	arg1	potential					993:1001	a zeta potential	986:1001	a zeta potential of about 11 mV	986:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	6	15	theme	mV	1015:1016	arg1	diameter					963:970	an average diameter	952:970	an average diameter of 193 nm	952:980	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	4	16	theme	optimal	675:681	arg1	formulation					683:693	the optimal formulation	671:693	the optimal formulation for the delivery of CEF	671:717	Central Composite design has been applied to get the optimal formulation for the delivery of CEF.					
34315365	5	17	theme	variables	740:748	arg1	effect					724:729	The effect	720:729	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs	720:850	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	10	18	from	rate	1260:1263	arg1	media					1283:1287	aqueous media	1275:1287	aqueous media	1275:1287	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	12	19	theme	higher	1506:1511	arg1	penetration					1513:1523	higher penetration	1506:1523	higher penetration of NPs from the rat intestine	1506:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	14	20	theme	controlled	1722:1731	arg1	delivery					1733:1740	the controlled delivery	1718:1740	the controlled delivery of CEF due to its antibacterial effectiveness	1718:1786	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	6	21	theme	monodispersed	915:927	arg1	distribution					934:945	a relatively monodispersed size distribution	902:945	a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV	902:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	5	22	theme	tripolyphosphate	790:805	arg1	concentration					763:775	the concentration	759:775	the concentration of chitosan, tripolyphosphate, and tween 80	759:819	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	8	23	theme	NPs	1106:1108	arg1	morphology					1092:1101	The surface morphology	1080:1101	The surface morphology of NPs	1080:1108	The surface morphology of NPs was observed by scanning electron microscopy.					
34315365	13	24	theme	optimized	1626:1634	arg1	formulation					1636:1646	the optimized formulation	1622:1646	the optimized formulation	1622:1646	The cell culture study showed the safety of the optimized formulation.					
34315365	2	25	dep	OBJECTIVE	352:360	arg1	was					401:403	was	401:403	was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally	401:486	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	10	26	theme	dissolution	1248:1258	arg1	acceptable					1293:1302	acceptable	1293:1302	acceptable	1293:1302	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	10	26	theme	dissolution	1248:1258	arg1	rate					1260:1263	The dissolution rate	1244:1263	The dissolution rate of NPs in aqueous media	1244:1287	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	1	27	theme	increased	188:196	arg1	resistance					198:207	the increased resistance	184:207	the increased resistance against existing antibiotics	184:236	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	2	28	theme	cefixime	466:473	arg1	rate					431:434	dissolution rate	419:434	dissolution rate	419:434	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	2	28	theme	cefixime	466:473	arg1	property					454:461	antibacterial property	440:461	antibacterial property	440:461	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	14	29	theme	antibacterial	1760:1772	arg1	effectiveness					1774:1786	its antibacterial effectiveness	1756:1786	its antibacterial effectiveness	1756:1786	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	13	30	theme	formulation	1636:1646	arg1	safety					1612:1617	the safety	1608:1617	the safety of the optimized formulation	1608:1646	The cell culture study showed the safety of the optimized formulation.					
34315365	10	31	theme	Peppas	1368:1373	arg1	model					1375:1379	the Peppas model	1364:1379	the Peppas model	1364:1379	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	3	32	contain	containing	558:567	arg1	NPs					553:555	NPs	553:555	NPs	553:555	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	3	32	contain	containing	558:567	arg1	nanoparticles					538:550	chitosan nanoparticles	529:550	chitosan nanoparticles (NPs) containing CEF	529:571	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	3	32	contain	containing	558:567	arg2	CEF					569:571	CEF	569:571	CEF	569:571	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	7	33	theme	tunneling	1032:1040	arg1	microscope					1042:1051	The scanning tunneling microscope	1019:1051	The scanning tunneling microscope	1019:1051	The scanning tunneling microscope confirmed the size of NPs.					
34315365	9	34	theme	amorphous	1196:1204	arg1	state					1206:1210	the amorphous state	1192:1210	the amorphous state of cefixime in the formulation	1192:1241	The calorimetric analysis indicated the amorphous state of cefixime in the formulation.					
34315365	6	35	with	distribution	934:945	arg1	potential					993:1001	a zeta potential	986:1001	a zeta potential of about 11 mV	986:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	6	35	with	distribution	934:945	arg1	diameter					963:970	an average diameter	952:970	an average diameter of 193 nm	952:980	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	3	36	theme	ionic	599:603	arg1	method					614:619	the ionic gelation method	595:619	the ionic gelation method	595:619	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	2	37	theme	antibacterial	440:452	arg1	property					454:461	antibacterial property	440:461	antibacterial property	440:461	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	5	38	theme	tween	812:816	arg1	concentration					763:775	the concentration	759:775	the concentration of chitosan, tripolyphosphate, and tween 80	759:819	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	12	39	theme	ex-vivo	1471:1477	arg1	study					1487:1491	The ex-vivo release study	1467:1491	The ex-vivo release study	1467:1491	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	10	40	theme	aqueous	1275:1281	arg1	media					1283:1287	aqueous media	1275:1287	aqueous media	1275:1287	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	1	41	theme	existing	217:224	arg1	antibiotics					226:236	existing antibiotics	217:236	existing antibiotics	217:236	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	0	42	theme	Release	43:49	arg1	Optimization					16:27	Optimization	16:27	Optimization	16:27	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	0	42	theme	Release	43:49	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	11	43	theme	CEF	1397:1399	arg1	efficient					1456:1464	efficient	1456:1464	efficient	1456:1464	The potency of CEF in NPs against various types of bacteria was hopefully efficient.					
34315365	11	43	theme	CEF	1397:1399	arg1	potency					1386:1392	The potency	1382:1392	The potency of CEF in NPs against various types of bacteria	1382:1440	The potency of CEF in NPs against various types of bacteria was hopefully efficient.					
34315365	0	44	theme	Antimicrobial	142:154	arg1	Activity					156:163	Its Antimicrobial Activity	138:163	Its Antimicrobial Activity	138:163	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	14	45	theme	Chitosan	1660:1667	arg1	NPs					1669:1671	CONCLUSION Chitosan NPs	1649:1671	CONCLUSION Chitosan NPs	1649:1671	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	2	46	dep	rate	431:434	arg1	the					415:417	the	415:417	the	415:417	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	12	47	theme	free	1567:1570	arg1	drug					1572:1575	free drug	1567:1575	free drug	1567:1575	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	0	48	theme	Controlled	32:41	arg1	Release					43:49	Controlled Release	32:49	Controlled Release	32:49	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	14	49	theme	CEF	1745:1747	arg1	delivery					1733:1740	the controlled delivery	1718:1740	the controlled delivery of CEF due to its antibacterial effectiveness	1718:1786	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	5	50	theme	NPs	848:850	arg1	characteristics					829:843	the characteristics	825:843	the characteristics of NPs	825:850	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	5	51	from	effect	724:729	arg1	characteristics					829:843	the characteristics	825:843	the characteristics of NPs	825:850	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	3	52	theme	gelation	605:612	arg1	method					614:619	the ionic gelation method	595:619	the ionic gelation method	595:619	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	2	53	theme	dissolution	419:429	arg1	rate					431:434	dissolution rate	419:434	dissolution rate	419:434	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	0	54	theme	Containing	65:74	arg1	Cefixime					76:83	Containing Cefixime	65:83	Containing Cefixime Using Central Composite Design	65:114	Preparation and Optimization of Controlled Release Nanoparticles Containing Cefixime Using Central Composite Design: An Attempt to Enrich Its Antimicrobial Activity.					
34315365	6	55	theme	size	929:932	arg1	distribution					934:945	a relatively monodispersed size distribution	902:945	a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV	902:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	12	56	from	intestine	1545:1553	arg1	penetration					1513:1523	higher penetration	1506:1523	higher penetration of NPs from the rat intestine	1506:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	12	56	from	intestine	1545:1553	arg1	NPs					1528:1530	NPs	1528:1530	NPs from the rat intestine	1528:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	6	57	theme	average	955:961	arg1	diameter					963:970	an average diameter	952:970	an average diameter of 193 nm	952:980	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	14	58	theme	CONCLUSION	1649:1658	arg1	NPs					1669:1671	CONCLUSION Chitosan NPs	1649:1671	CONCLUSION Chitosan NPs	1649:1671	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	13	59	theme	cell	1582:1585	arg1	study					1595:1599	The cell culture study	1578:1599	The cell culture study	1578:1599	The cell culture study showed the safety of the optimized formulation.					
34315365	4	60	theme	CEF	715:717	arg1	delivery					703:710	the delivery	699:710	the delivery of CEF	699:717	Central Composite design has been applied to get the optimal formulation for the delivery of CEF.					
34315365	7	61	theme	scanning	1023:1030	arg1	microscope					1042:1051	The scanning tunneling microscope	1019:1051	The scanning tunneling microscope	1019:1051	The scanning tunneling microscope confirmed the size of NPs.					
34315365	1	62	theme	resistant	331:339	arg1	pathogens					341:349	resistant pathogens	331:349	resistant pathogens	331:349	BACKGROUND Due to the increased resistance against existing antibiotics, research is essential to discover new and alternative ways to control infections induced by resistant pathogens.					
34315365	9	63	theme	cefixime	1215:1222	arg1	state					1206:1210	the amorphous state	1192:1210	the amorphous state of cefixime in the formulation	1192:1241	The calorimetric analysis indicated the amorphous state of cefixime in the formulation.					
34315365	11	64	theme	bacteria	1433:1440	arg1	types					1424:1428	various types	1416:1428	various types of bacteria	1416:1440	The potency of CEF in NPs against various types of bacteria was hopefully efficient.					
34315365	12	65	theme	rat	1541:1543	arg1	intestine					1545:1553	the rat intestine	1537:1553	the rat intestine	1537:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	8	66	theme	surface	1084:1090	arg1	morphology					1092:1101	The surface morphology	1080:1101	The surface morphology of NPs	1080:1108	The surface morphology of NPs was observed by scanning electron microscopy.					
34315365	14	67	theme	significant	1695:1705	arg1	system					1707:1712	a significant system	1693:1712	a significant system for the controlled delivery of CEF due to its antibacterial effectiveness	1693:1786	CONCLUSION Chitosan NPs could be considered a significant system for the controlled delivery of CEF due to its antibacterial effectiveness.					
34315365	13	68	theme	culture	1587:1593	arg1	study					1595:1599	The cell culture study	1578:1599	The cell culture study	1578:1599	The cell culture study showed the safety of the optimized formulation.					
34315365	10	69	from	NPs	1351:1353	arg1	CEF					1342:1344	CEF	1342:1344	CEF from NPs	1342:1353	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	3	70	theme	chitosan	529:536	arg1	NPs					553:555	NPs	553:555	NPs	553:555	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	3	70	theme	chitosan	529:536	arg1	nanoparticles					538:550	chitosan nanoparticles	529:550	chitosan nanoparticles (NPs) containing CEF	529:571	METHODS To achieve the desired results, chitosan nanoparticles (NPs) containing CEF were fabricated using the ionic gelation method.					
34315365	9	71	theme	calorimetric	1160:1171	arg1	analysis					1173:1180	The calorimetric analysis	1156:1180	The calorimetric analysis	1156:1180	The calorimetric analysis indicated the amorphous state of cefixime in the formulation.					
34315365	12	72	theme	NPs	1528:1530	arg1	penetration					1513:1523	higher penetration	1506:1523	higher penetration of NPs from the rat intestine	1506:1553	The ex-vivo release study demonstrated higher penetration of NPs from the rat intestine compared to free drug.					
34315365	11	73	from	potency	1386:1392	arg1	NPs					1404:1406	NPs	1404:1406	NPs against various types of bacteria	1404:1440	The potency of CEF in NPs against various types of bacteria was hopefully efficient.					
34315365	10	74	theme	kinetics	1329:1336	arg1	model					1312:1316	the model	1308:1316	the model of release kinetics for CEF from NPs	1308:1353	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	2	75	theme	scrutinization	386:399	arg1	goal					366:369	The goal	362:369	The goal of the current scrutinization	362:399	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	6	76	theme	nm	979:980	arg1	potential					993:1001	a zeta potential	986:1001	a zeta potential of about 11 mV	986:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	6	76	theme	nm	979:980	arg1	diameter					963:970	an average diameter	952:970	an average diameter of 193 nm	952:980	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	4	77	theme	Composite	630:638	arg1	design					640:645	Central Composite design	622:645	Central Composite design	622:645	Central Composite design has been applied to get the optimal formulation for the delivery of CEF.					
34315365	5	78	theme	chitosan	780:787	arg1	concentration					763:775	the concentration	759:775	the concentration of chitosan, tripolyphosphate, and tween 80	759:819	The effect of three variables, such as the concentration of chitosan, tripolyphosphate, and tween 80, on the characteristics of NPs was evaluated.					
34315365	6	79	dep	RESULTS	867:873	arg1	involved					893:900	involved	893:900	involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV	893:1016	RESULTS The optimized NPs involved a relatively monodispersed size distribution with an average diameter of 193 nm and a zeta potential of about 11 mV.					
34315365	10	80	theme	release	1321:1327	arg1	kinetics					1329:1336	release kinetics	1321:1336	release kinetics	1321:1336	The dissolution rate of NPs in aqueous media was acceptable and the model of release kinetics for CEF from NPs followed the Peppas model.					
34315365	2	81	theme	current	378:384	arg1	scrutinization					386:399	the current scrutinization	374:399	the current scrutinization	374:399	OBJECTIVE The goal of the current scrutinization was to enrich the dissolution rate and antibacterial property of cefixime (CEF) orally.					
34315365	9	82	from	state	1206:1210	arg1	formulation					1231:1241	the formulation	1227:1241	the formulation	1227:1241	The calorimetric analysis indicated the amorphous state of cefixime in the formulation.					
34315365	4	83	theme	Central	622:628	arg1	design					640:645	Central Composite design	622:645	Central Composite design	622:645	Central Composite design has been applied to get the optimal formulation for the delivery of CEF.					
35914466	5	0	from	adhesion	854:861	arg1	alloys					915:920	coated Zn alloys	905:920	coated Zn alloys	905:920	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	3	1	theme	polycarbonate/heparin	522:542	arg1	composite					544:552	a zinc ion-crosslinked polycarbonate/heparin composite	499:552	a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD)	499:597	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	6	2	theme	coating	1057:1063	arg1	erosion					1032:1038	the surface erosion	1020:1038	the surface erosion of the composite coating	1020:1063	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	5	3	theme	faster	953:958	arg1	reendothelialization					960:979	faster reendothelialization	953:979	faster reendothelialization than that on bare Zn alloys	953:1007	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	1	4	theme	due	193:195	arg1	stents					186:191	biodegradable cardiovascular stents	157:191	biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature	157:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	6	5	theme	composite	1047:1055	arg1	coating					1057:1063	the composite coating	1043:1063	the composite coating	1043:1063	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	4	6	theme	alloys	837:842	arg1	resistance					779:788	an enhanced corrosion resistance	757:788	an enhanced corrosion resistance	757:788	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	4	6	theme	alloys	837:842	arg1	rate					815:818	lower Zn ion release rate	794:818	lower Zn ion release rate of the coated Zn alloys	794:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	7	theme	Enhanced	845:852	arg1	adhesion					854:861	adhesion	854:861	adhesion	854:861	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	4	8	theme	release	807:813	arg1	rate					815:818	lower Zn ion release rate	794:818	lower Zn ion release rate of the coated Zn alloys	794:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	9	theme	Zn	999:1000	arg1	alloys					1002:1007	bare Zn alloys	994:1007	bare Zn alloys	994:1007	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	6	10	theme	Zn-alloy	1219:1226	arg1	stents					1228:1233	the coated Zn-alloy stents	1208:1233	the coated Zn-alloy stents	1208:1233	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	0	11	link	Ion-crosslinked	5:19	arg1	coatings					53:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings	0:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.	0:107	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	4	12	theme	enhanced	760:767	arg1	resistance					779:788	an enhanced corrosion resistance	757:788	an enhanced corrosion resistance	757:788	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	13	theme	bare	994:997	arg1	alloys					1002:1007	bare Zn alloys	994:1007	bare Zn alloys	994:1007	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	2	14	theme	rapid	303:307	arg1	release					309:315	the rapid release	299:315	the rapid release of zinc ions during the initial degradation stage	299:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	15	theme	function	400:407	arg1	cytotoxicity					276:287	the cytotoxicity	272:287	the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage	272:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	15	theme	function	400:407	arg1	challenges					418:427	huge challenges	413:427	huge challenges for their practical clinical applications	413:469	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	15	theme	function	400:407	arg1	lack					375:378	the lack	371:378	the lack of an anticoagulant function	371:407	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	16	theme	huge	413:416	arg1	cytotoxicity					276:287	the cytotoxicity	272:287	the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage	272:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	16	theme	huge	413:416	arg1	challenges					418:427	huge challenges	413:427	huge challenges for their practical clinical applications	413:469	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	16	theme	huge	413:416	arg1	lack					375:378	the lack	371:378	the lack of an anticoagulant function	371:407	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	4	17	theme	coated	827:832	arg1	alloys					837:842	the coated Zn alloys	823:842	the coated Zn alloys	823:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	0	18	theme	Ion-crosslinked	5:19	arg1	coatings					53:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings	0:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.	0:107	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	5	19	from	proliferation	867:879	arg1	alloys					915:920	coated Zn alloys	905:920	coated Zn alloys	905:920	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	4	20	theme	ion	803:805	arg1	rate					815:818	lower Zn ion release rate	794:818	lower Zn ion release rate of the coated Zn alloys	794:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	1	21	theme	good	206:209	arg1	rate					221:224	their good corrosion rate	200:224	their good corrosion rate	200:224	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	0	22	theme	Zinc	0:3	arg1	coatings					53:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings	0:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.	0:107	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	6	23	theme	long-term	1240:1248	arg1	functions					1264:1272	long-term anticoagulant functions	1240:1272	long-term anticoagulant functions	1240:1272	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	6	24	theme	long-term	1088:1096	arg1	release					1098:1104	the uniform and long-term release	1072:1104	the uniform and long-term release	1072:1104	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	4	25	theme	Zn	800:801	arg1	rate					815:818	lower Zn ion release rate	794:818	lower Zn ion release rate of the coated Zn alloys	794:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	2	26	theme	anticoagulant	386:398	arg1	function					400:407	an anticoagulant function	383:407	an anticoagulant function	383:407	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	0	27	theme	composite	43:51	arg1	coatings					53:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings	0:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.	0:107	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	6	28	theme	surface	1024:1030	arg1	erosion					1032:1038	the surface erosion	1020:1038	the surface erosion of the composite coating	1020:1063	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	2	29	theme	ions	325:328	arg1	release					309:315	the rapid release	299:315	the rapid release of zinc ions during the initial degradation stage	299:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	2	30	theme	practical	439:447	arg1	applications					458:469	their practical clinical applications	433:469	their practical clinical applications	433:469	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	0	31	theme	polycarbonate/heparin	21:41	arg1	coatings					53:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings	0:60	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.	0:107	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	3	32	theme	electrophoretic	566:580	arg1	EPD					594:596	EPD	594:596	EPD	594:596	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	3	32	theme	electrophoretic	566:580	arg1	deposition					582:591	electrophoretic deposition	566:591	electrophoretic deposition (EPD)	566:597	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	2	33	theme	zinc	320:323	arg1	ions					325:328	zinc ions	320:328	zinc ions	320:328	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	3	34	theme	ion-crosslinked	506:520	arg1	composite					544:552	a zinc ion-crosslinked polycarbonate/heparin composite	499:552	a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD)	499:597	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	6	35	theme	platelets	1176:1184	arg1	adhesion					1149:1156	adhesion	1149:1156	adhesion	1149:1156	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	6	35	theme	platelets	1176:1184	arg1	activation					1162:1171	activation	1162:1171	activation	1162:1171	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	1	36	theme	corrosion	211:219	arg1	rate					221:224	their good corrosion rate	200:224	their good corrosion rate	200:224	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	5	37	theme	coated	905:910	arg1	alloys					915:920	coated Zn alloys	905:920	coated Zn alloys	905:920	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	4	38	theme	in	719:720	arg1	tests					738:742	in vitro immersion tests	719:742	in vitro immersion tests	719:742	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	3	39	theme	anticoagulant	643:655	arg1	functions					657:665	anticoagulant functions	643:665	anticoagulant functions for Zn-alloy stents	643:685	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	1	40	from	biocompatibility	230:245	arg1	vasculature					250:260	vasculature	250:260	vasculature	250:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	4	41	theme	electrochemical	693:707	arg1	tests					709:713	electrochemical tests	693:713	electrochemical tests	693:713	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	0	42	theme	Zn-alloy	80:87	arg1	applications					95:106	biodegradable Zn-alloy stent applications	66:106	biodegradable Zn-alloy stent applications	66:106	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	4	43	theme	immersion	728:736	arg1	tests					738:742	in vitro immersion tests	719:742	in vitro immersion tests	719:742	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	44	theme	endothelial	884:894	arg1	cells					896:900	endothelial cells	884:900	endothelial cells	884:900	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	3	45	theme	zinc	501:504	arg1	composite					544:552	a zinc ion-crosslinked polycarbonate/heparin composite	499:552	a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD)	499:597	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	0	46	theme	biodegradable	66:78	arg1	applications					95:106	biodegradable Zn-alloy stent applications	66:106	biodegradable Zn-alloy stent applications	66:106	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	6	47	with	endowed	1200:1206	arg1	functions					1264:1272	long-term anticoagulant functions	1240:1272	long-term anticoagulant functions	1240:1272	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	6	48	theme	heparin	1109:1115	arg1	release					1098:1104	the uniform and long-term release	1072:1104	the uniform and long-term release	1072:1104	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	6	49	dep	adhesion	1149:1156	arg1	the					1145:1147	the	1145:1147	the	1145:1147	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	1	50	from	rate	221:224	arg1	vasculature					250:260	vasculature	250:260	vasculature	250:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	1	51	theme	best	137:140	arg1	candidates					142:151	the best candidates	133:151	the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature	133:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	1	51	theme	best	137:140	arg1	Zinc					109:112	Zinc	109:112	Zinc	109:112	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	1	51	theme	best	137:140	arg1	alloys					122:127	its alloys	118:127	its alloys	118:127	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	3	52	theme	Zn-alloy	671:678	arg1	stents					680:685	Zn-alloy stents	671:685	Zn-alloy stents	671:685	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	2	53	theme	degradation	349:359	arg1	stage					361:365	the initial degradation stage	337:365	the initial degradation stage	337:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	6	54	theme	uniform	1076:1082	arg1	release					1098:1104	the uniform and long-term release	1072:1104	the uniform and long-term release	1072:1104	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	3	55	link	ion-crosslinked	506:520	arg1	composite					544:552	a zinc ion-crosslinked polycarbonate/heparin composite	499:552	a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD)	499:597	In this work, we developed a zinc ion-crosslinked polycarbonate/heparin composite coating via electrophoretic deposition (EPD) to improve the biocompatibility and provide anticoagulant functions for Zn-alloy stents.					
35914466	4	56	theme	Zn	834:835	arg1	alloys					837:842	the coated Zn alloys	823:842	the coated Zn alloys	823:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	2	57	theme	initial	341:347	arg1	stage					361:365	the initial degradation stage	337:365	the initial degradation stage	337:365	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	6	58	theme	anticoagulant	1250:1262	arg1	functions					1264:1272	long-term anticoagulant functions	1240:1272	long-term anticoagulant functions	1240:1272	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	4	59	theme	lower	794:798	arg1	rate					815:818	lower Zn ion release rate	794:818	lower Zn ion release rate of the coated Zn alloys	794:842	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	60	theme	Zn	912:913	arg1	alloys					915:920	coated Zn alloys	905:920	coated Zn alloys	905:920	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	4	61	dep	in	719:720	arg1	vitro					722:726	vitro	722:726	vitro	722:726	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
35914466	5	62	theme	cells	896:900	arg1	proliferation					867:879	proliferation	867:879	proliferation	867:879	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	5	62	theme	cells	896:900	arg1	adhesion					854:861	adhesion	854:861	adhesion	854:861	Enhanced adhesion and proliferation of endothelial cells on coated Zn alloys were also observed, indicating faster reendothelialization than that on bare Zn alloys.					
35914466	1	63	theme	biodegradable	157:169	arg1	stents					186:191	biodegradable cardiovascular stents	157:191	biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature	157:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	6	64	theme	coated	1212:1217	arg1	stents					1228:1233	the coated Zn-alloy stents	1208:1233	the coated Zn-alloy stents	1208:1233	Moreover, the surface erosion of the composite coating led to the uniform and long-term release of heparin, which remarkably inhibited the adhesion and activation of platelets, and may have endowed the coated Zn-alloy stents with long-term anticoagulant functions.					
35914466	0	65	theme	stent	89:93	arg1	applications					95:106	biodegradable Zn-alloy stent applications	66:106	biodegradable Zn-alloy stent applications	66:106	Zinc Ion-crosslinked polycarbonate/heparin composite coatings for biodegradable Zn-alloy stent applications.					
35914466	2	66	theme	clinical	449:456	arg1	applications					458:469	their practical clinical applications	433:469	their practical clinical applications	433:469	However, the cytotoxicity caused by the rapid release of zinc ions during the initial degradation stage and the lack of an anticoagulant function are huge challenges for their practical clinical applications.					
35914466	1	67	theme	cardiovascular	171:184	arg1	stents					186:191	biodegradable cardiovascular stents	157:191	biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature	157:260	Zinc and its alloys are the best candidates for biodegradable cardiovascular stents due to their good corrosion rate and biocompatibility in vasculature.					
35914466	4	68	theme	corrosion	769:777	arg1	resistance					779:788	an enhanced corrosion resistance	757:788	an enhanced corrosion resistance	757:788	Both electrochemical tests and in vitro immersion tests demonstrated an enhanced corrosion resistance and lower Zn ion release rate of the coated Zn alloys.					
36278802	4	0	theme	BG	645:646	arg1	effect					635:640	the effect	631:640	the effect of BG from highland barley on western diet (WD) induced NAFLD mice	631:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	7	1	theme	farnesoid	974:982	arg1	FXR					996:998	FXR	996:998	FXR	996:998	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	1	theme	farnesoid	974:982	arg1	receptor					986:993	farnesoid X receptor	974:993	farnesoid X receptor (FXR) signaling in the liver	974:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	1	2	theme	Non-alcoholic	170:182	arg1	NAFLD					205:209	NAFLD	205:209	NAFLD	205:209	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	1	2	theme	Non-alcoholic	170:182	arg1	disease					196:202	Non-alcoholic fatty liver disease	170:202	Non-alcoholic fatty liver disease (NAFLD)	170:210	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	7	3	theme	X	984:984	arg1	FXR					996:998	FXR	996:998	FXR	996:998	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	3	theme	X	984:984	arg1	receptor					986:993	farnesoid X receptor	974:993	farnesoid X receptor (FXR) signaling in the liver	974:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	4	theme	signaling	1001:1009	arg1	inhibition					1028:1037	inhibition	1028:1037	inhibition of FXR signaling in the ileum	1028:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	4	theme	signaling	1001:1009	arg1	activation					960:969	the activation	956:969	the activation of farnesoid X receptor (FXR) signaling in the liver	956:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	5	from	ileum	1063:1067	arg1	inhibition					1028:1037	inhibition	1028:1037	inhibition of FXR signaling in the ileum	1028:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	5	from	ileum	1063:1067	arg1	activation					960:969	the activation	956:969	the activation of farnesoid X receptor (FXR) signaling in the liver	956:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	6	theme	signaling	1046:1054	arg1	inhibition					1028:1037	inhibition	1028:1037	inhibition of FXR signaling in the ileum	1028:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	6	theme	signaling	1046:1054	arg1	activation					960:969	the activation	956:969	the activation of farnesoid X receptor (FXR) signaling in the liver	956:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	7	theme	hepatic	915:921	arg1	BAs					923:925	hepatic BAs	915:925	hepatic BAs	915:925	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	1	8	theme	fatty	184:188	arg1	NAFLD					205:209	NAFLD	205:209	NAFLD	205:209	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	1	8	theme	fatty	184:188	arg1	disease					196:202	Non-alcoholic fatty liver disease	170:202	Non-alcoholic fatty liver disease (NAFLD)	170:210	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	4	9	from	effect	635:640	arg1	NAFLD					698:702	NAFLD	698:702	NAFLD	698:702	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	9	from	effect	635:640	arg1	WD					686:687	WD	686:687	WD	686:687	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	9	from	effect	635:640	arg1	barley					662:667	highland barley	653:667	highland barley	653:667	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	9	from	effect	635:640	arg1	diet					680:683	western diet	672:683	western diet (WD) induced NAFLD mice	672:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	9	from	effect	635:640	arg1	mice					704:707	mice	704:707	mice	704:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	7	10	theme	FXR	1042:1044	arg1	signaling					1046:1054	FXR signaling	1042:1054	FXR signaling in the ileum	1042:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	3	11	theme	cereal	387:392	arg1	BG					404:405	BG	404:405	BG	404:405	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	3	11	theme	cereal	387:392	arg1	β-glucan					394:401	cereal β-glucan	387:401	cereal β-glucan (BG)	387:406	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	2	12	theme	and energy	287:296	arg1	expenditure					298:308	bile acids (BAs) metabolism and energy expenditure	259:308	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	12	theme	and energy	287:296	arg1	therapies					324:332	potential therapies	314:332	potential therapies for NAFLD	314:342	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	3	13	theme	β-glucan	394:401	arg1	effects					376:382	the main health effects	360:382	the main health effects of cereal β-glucan (BG)	360:406	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	0	14	theme	energy	106:111	arg1	expenditure					113:123	energy expenditure	106:123	energy expenditure	106:123	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	6	15	theme	energy	842:847	arg1	expenditure					849:859	an increased energy expenditure	829:859	an increased energy expenditure	829:859	These moderating effects were associated with an increased energy expenditure.					
36278802	3	16	theme	BAs	517:519	arg1	metabolism					503:512	the metabolism	499:512	the metabolism of BAs	499:519	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	2	17	theme	metabolism	276:285	arg1	expenditure					298:308	bile acids (BAs) metabolism and energy expenditure	259:308	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	17	theme	metabolism	276:285	arg1	therapies					324:332	potential therapies	314:332	potential therapies for NAFLD	314:342	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	7	18	from	signaling	1001:1009	arg1	liver					1018:1022	the liver	1014:1022	the liver	1014:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	6	19	theme	increased	832:840	arg1	expenditure					849:859	an increased energy expenditure	829:859	an increased energy expenditure	829:859	These moderating effects were associated with an increased energy expenditure.					
36278802	8	20	theme	fat	1107:1109	arg1	accumulation					1111:1122	fat accumulation	1107:1122	fat accumulation	1107:1122	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	1	21	theme	liver	190:194	arg1	NAFLD					205:209	NAFLD	205:209	NAFLD	205:209	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	1	21	theme	liver	190:194	arg1	disease					196:202	Non-alcoholic fatty liver disease	170:202	Non-alcoholic fatty liver disease (NAFLD)	170:210	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	8	22	theme	energy	1138:1143	arg1	mechanism					1160:1168	a mechanism	1158:1168	a mechanism associated with major changes in the composition of hepatic BAs	1158:1232	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	8	22	theme	energy	1138:1143	arg1	expenditure					1145:1155	energy expenditure	1138:1155	energy expenditure	1138:1155	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	1	23	theme	health	232:237	arg1	burden					239:244	a public health burden	223:244	a public health burden	223:244	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	0	24	theme	barley	9:14	arg1	β-glucan					16:23	Highland barley β-glucan	0:23	Highland barley β-glucan	0:23	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	0	25	theme	Highland	0:7	arg1	β-glucan					16:23	Highland barley β-glucan	0:23	Highland barley β-glucan	0:23	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	7	26	theme	BG-treated	872:881	arg1	mice					883:886	BG-treated mice	872:886	BG-treated mice	872:886	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	2	27	theme	potential	314:322	arg1	expenditure					298:308	bile acids (BAs) metabolism and energy expenditure	259:308	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	27	theme	potential	314:322	arg1	therapies					324:332	potential therapies	314:332	potential therapies for NAFLD	314:342	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	8	28	from	changes	1192:1198	arg1	composition					1207:1217	the composition	1203:1217	the composition of hepatic BAs	1203:1232	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	3	29	theme	health	369:374	arg1	effects					376:382	the main health effects	360:382	the main health effects of cereal β-glucan (BG)	360:406	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	4	30	theme	western	672:678	arg1	WD					686:687	WD	686:687	WD	686:687	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	30	theme	western	672:678	arg1	NAFLD					698:702	NAFLD	698:702	NAFLD	698:702	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	30	theme	western	672:678	arg1	diet					680:683	western diet	672:683	western diet (WD) induced NAFLD mice	672:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	30	theme	western	672:678	arg1	mice					704:707	mice	704:707	mice	704:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	0	31	theme	acid	145:148	arg1	metabolism					150:159	bile acid metabolism	140:159	bile acid metabolism in mice	140:167	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	5	32	theme	adipose	764:770	arg1	lipolysis					772:780	increased adipose lipolysis	754:780	increased adipose lipolysis	754:780	BG treatment prevented fat accumulation and increased adipose lipolysis.					
36278802	3	33	theme	effects	376:382	arg1	effects					376:382	the main health effects	360:382	the main health effects of cereal β-glucan (BG)	360:406	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	3	33	theme	effects	376:382	arg1	one					353:355	one	353:355	one	353:355	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	7	34	from	liver	1018:1022	arg1	inhibition					1028:1037	inhibition	1028:1037	inhibition of FXR signaling in the ileum	1028:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	34	from	liver	1018:1022	arg1	activation					960:969	the activation	956:969	the activation of farnesoid X receptor (FXR) signaling in the liver	956:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	0	35	theme	bile	140:143	arg1	metabolism					150:159	bile acid metabolism	140:159	bile acid metabolism in mice	140:167	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	0	36	theme	diet-induced	44:55	arg1	disease					83:89	western diet-induced non-alcoholic fatty liver disease	36:89	western diet-induced non-alcoholic fatty liver disease	36:89	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	4	37	theme	BAs	609:611	arg1	profiling					588:596	the profiling	584:596	the profiling of hepatic BAs	584:611	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	38	dep	induced	690:696	arg1	NAFLD					698:702	NAFLD	698:702	NAFLD	698:702	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	38	dep	induced	690:696	arg1	diet					680:683	western diet	672:683	western diet (WD) induced NAFLD mice	672:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	38	dep	induced	690:696	arg1	mice					704:707	mice	704:707	mice	704:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	3	39	theme	lower	426:430	arg1	cholesterol					432:442	lower cholesterol	426:442	lower cholesterol	426:442	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	0	40	theme	western	36:42	arg1	disease					83:89	western diet-induced non-alcoholic fatty liver disease	36:89	western diet-induced non-alcoholic fatty liver disease	36:89	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	7	41	from	inhibition	1028:1037	arg1	ileum					1063:1067	the ileum	1059:1067	the ileum	1059:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	41	from	inhibition	1028:1037	arg1	liver					1018:1022	the liver	1014:1022	the liver	1014:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	5	42	theme	BG	710:711	arg1	treatment					713:721	BG treatment	710:721	BG treatment	710:721	BG treatment prevented fat accumulation and increased adipose lipolysis.					
36278802	4	43	theme	hepatic	601:607	arg1	BAs					609:611	hepatic BAs	601:611	hepatic BAs	601:611	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	0	44	theme	fatty	71:75	arg1	disease					83:89	western diet-induced non-alcoholic fatty liver disease	36:89	western diet-induced non-alcoholic fatty liver disease	36:89	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	5	45	theme	increased	754:762	arg1	lipolysis					772:780	increased adipose lipolysis	754:780	increased adipose lipolysis	754:780	BG treatment prevented fat accumulation and increased adipose lipolysis.					
36278802	6	46	theme	moderating	789:798	arg1	effects					800:806	These moderating effects	783:806	These moderating effects	783:806	These moderating effects were associated with an increased energy expenditure.					
36278802	4	47	theme	highland	653:660	arg1	barley					662:667	highland barley	653:667	highland barley	653:667	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	0	48	theme	non-alcoholic	57:69	arg1	disease					83:89	western diet-induced non-alcoholic fatty liver disease	36:89	western diet-induced non-alcoholic fatty liver disease	36:89	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	7	49	theme	receptor	986:993	arg1	signaling					1001:1009	farnesoid X receptor (FXR) signaling	974:1009	farnesoid X receptor (FXR) signaling in the liver	974:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	4	50	theme	metabolic	555:563	arg1	tests					565:569	metabolic tests	555:569	metabolic tests coupled with the profiling of hepatic BAs	555:611	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	7	51	from	signaling	1046:1054	arg1	ileum					1063:1067	the ileum	1059:1067	the ileum	1059:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	52	theme	BAs	923:925	arg1	production					901:910	the production	897:910	the production of hepatic BAs	897:925	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	8	53	theme	hepatic	1222:1228	arg1	BAs					1230:1232	hepatic BAs	1222:1232	hepatic BAs	1222:1232	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	4	54	from	barley	662:667	arg1	BG					645:646	BG	645:646	BG from highland barley	645:667	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	4	54	from	barley	662:667	arg1	effect					635:640	the effect	631:640	the effect of BG from highland barley on western diet (WD) induced NAFLD mice	631:707	Therefore, by using metabolic tests coupled with the profiling of hepatic BAs, we have assessed the effect of BG from highland barley on western diet (WD) induced NAFLD mice.					
36278802	1	55	theme	public	225:230	arg1	burden					239:244	a public health burden	223:244	a public health burden	223:244	Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.					
36278802	3	56	theme	metabolism	503:512	arg1	imbalances					485:494	imbalances	485:494	imbalances of the metabolism of BAs	485:519	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36278802	2	57	theme	acids	264:268	arg1	expenditure					298:308	bile acids (BAs) metabolism and energy expenditure	259:308	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	57	theme	acids	264:268	arg1	therapies					324:332	potential therapies	314:332	potential therapies for NAFLD	314:342	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	8	58	theme	BAs	1230:1232	arg1	composition					1207:1217	the composition	1203:1217	the composition of hepatic BAs	1203:1232	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	0	59	from	metabolism	150:159	arg1	mice					164:167	mice	164:167	mice	164:167	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	7	60	from	activation	960:969	arg1	ileum					1063:1067	the ileum	1059:1067	the ileum	1059:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	7	60	from	activation	960:969	arg1	liver					1018:1022	the liver	1014:1022	the liver	1014:1022	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	2	61	theme	bile	259:262	arg1	BAs					271:273	BAs	271:273	BAs	271:273	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	61	theme	bile	259:262	arg1	acids					264:268	bile acids	259:268	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	8	62	theme	major	1186:1190	arg1	changes					1192:1198	major changes	1186:1198	major changes in the composition of hepatic BAs	1186:1232	Our results suggest that BG prevents fat accumulation by increasing energy expenditure, a mechanism associated with major changes in the composition of hepatic BAs.					
36278802	0	63	theme	liver	77:81	arg1	disease					83:89	western diet-induced non-alcoholic fatty liver disease	36:89	western diet-induced non-alcoholic fatty liver disease	36:89	Highland barley β-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice.					
36278802	7	64	dep	enhanced	888:895	arg1	connected					941:949	connected	941:949	may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum	934:1067	Moreover, BG-treated mice enhanced the production of hepatic BAs, which may be connected with the activation of farnesoid X receptor (FXR) signaling in the liver and inhibition of FXR signaling in the ileum.					
36278802	2	65	theme	Controlling	247:257	arg1	expenditure					298:308	bile acids (BAs) metabolism and energy expenditure	259:308	Controlling bile acids (BAs) metabolism and energy expenditure	247:308	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	2	65	theme	Controlling	247:257	arg1	therapies					324:332	potential therapies	314:332	potential therapies for NAFLD	314:342	Controlling bile acids (BAs) metabolism and energy expenditure are potential therapies for NAFLD.					
36278802	5	66	theme	fat	733:735	arg1	accumulation					737:748	fat accumulation	733:748	fat accumulation	733:748	BG treatment prevented fat accumulation and increased adipose lipolysis.					
36278802	3	67	theme	main	364:367	arg1	effects					376:382	the main health effects	360:382	the main health effects of cereal β-glucan (BG)	360:406	Because one of the main health effects of cereal β-glucan (BG) is its ability to lower cholesterol by interacting with BAs, BG may regulate imbalances of the metabolism of BAs during NAFLD.					
36126300	12	0	theme	bacteria	1692:1699	arg1	distribution					1676:1687	The uniform distribution	1664:1687	The uniform distribution of bacteria in CPAs	1664:1707	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	3	1	theme	farcinica	501:509	arg1	technology					478:487	the cryopreservation technology	457:487	the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria)	457:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	12	2	from	calorimeter	1897:1907	arg1	results					1860:1866	the experimental results	1843:1866	the experimental results from a differential scanning calorimeter	1843:1907	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	5	3	dep	CPAs	788:791	arg1	milk					873:876	skim milk	868:876	skim milk	868:876	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	glycol					814:819	propylene glycol	804:819	propylene glycol	804:819	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	sucrose					822:828	sucrose	822:828	sucrose	822:828	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	l-proline					853:861	l-proline	853:861	l-proline	853:861	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	CPAs					788:791	CPAs	788:791	CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk)	788:877	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	glycerol					794:801	glycerol	794:801	glycerol	794:801	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	glucose					831:837	glucose	831:837	glucose	831:837	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	3	dep	CPAs	788:791	arg1	l-carnitine					840:850	l-carnitine	840:850	l-carnitine	840:850	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	9	4	theme	8.46 M	1368:1373	arg1	glycerin					1375:1382	8.46 M glycerin	1368:1382	8.46 M glycerin	1368:1382	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	12	5	theme	scanning	1888:1895	arg1	calorimeter					1897:1907	a differential scanning calorimeter	1873:1907	a differential scanning calorimeter	1873:1907	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	1	6	theme	Pathogenic	106:115	arg1	resources					156:164	valuable biological resources	136:164	valuable biological resources	136:164	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	1	6	theme	Pathogenic	106:115	arg1	microorganisms					117:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	4	7	theme	temperature	646:656	arg1	effects					602:608	The effects	598:608	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process	598:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	8	8	theme	optimal	1205:1211	arg1	CPA					1223:1225	The optimal composite CPA	1201:1225	The optimal composite CPA for N. farcinica	1201:1242	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	8	8	theme	optimal	1205:1211	arg1	sucrose					1255:1261	0.292 M sucrose	1247:1261	0.292 M sucrose	1247:1261	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	2	9	theme	microbial	307:315	arg1	resources					317:325	the microbial resources	303:325	the microbial resources	303:325	It is very important to properly preserve the microbial resources by methods to maintain the purity, viability, and integrity, and to avoid prolonged degradation.					
36126300	9	10	theme	0.292 M	1389:1395	arg1	sucrose					1397:1403	0.292 M sucrose	1389:1403	0.292 M sucrose	1389:1403	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	3	11	theme	vaccine	556:562	arg1	strains					564:570	vaccine strains	556:570	vaccine strains (Gram-negative bacteria)	556:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	3	11	theme	vaccine	556:562	arg1	bacteria					587:594	Gram-negative bacteria	573:594	Gram-negative bacteria	573:594	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	8	12	theme	N.	1231:1232	arg1	farcinica					1234:1242	N. farcinica	1231:1242	N. farcinica	1231:1242	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	13	13	theme	microorganisms	2024:2037	arg1	resources					2000:2008	precious natural biological resources	1972:2008	precious natural biological resources of pathogenic microorganisms	1972:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	1	14	theme	environmental	213:225	arg1	protection					227:236	environmental protection	213:236	environmental protection	213:236	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	13	15	theme	precious	1972:1979	arg1	resources					2000:2008	precious natural biological resources	1972:2008	precious natural biological resources of pathogenic microorganisms	1972:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	0	16	dep	farcinica	59:67	arg1	strains					97:103	vaccine strains	89:103	vaccine strains	89:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	13	17	theme	biological	1989:1998	arg1	resources					2000:2008	precious natural biological resources	1972:2008	precious natural biological resources of pathogenic microorganisms	1972:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	1	18	theme	valuable	136:143	arg1	resources					156:164	valuable biological resources	136:164	valuable biological resources	136:164	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	1	18	theme	valuable	136:143	arg1	microorganisms					117:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	4	19	theme	cycles	675:680	arg1	effects					602:608	The effects	598:608	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process	598:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	8	20	theme	2.82 M	1288:1293	arg1	glycerol					1295:1302	2.82 M glycerol	1288:1302	2.82 M glycerol	1288:1302	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	0	21	theme	pestis	82:87	arg1	Survival					38:45	the Survival	34:45	the Survival of Nocardia farcinica and Yersinia pestis vaccine strains	34:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	12	22	theme	strains	1814:1820	arg1	cryopreservation					1794:1809	the cryopreservation	1790:1809	the cryopreservation of strains	1790:1820	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	5	23	theme	farcinica	931:939	arg1	rates					915:919	the survival rates	902:919	the survival rates of the N. farcinica and Y. pestis vaccine strains	902:969	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	6	24	theme	biochemical	1021:1031	arg1	toxicity					1033:1040	biochemical toxicity	1021:1040	biochemical toxicity	1021:1040	However, high concentrations of CPAs can produce biochemical toxicity in the two pathogens.					
36126300	0	25	theme	farcinica	59:67	arg1	Survival					38:45	the Survival	34:45	the Survival of Nocardia farcinica and Yersinia pestis vaccine strains	34:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	3	26	dep	farcinica	501:509	arg1	strains					564:570	vaccine strains	556:570	vaccine strains (Gram-negative bacteria)	556:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	3	26	dep	farcinica	501:509	arg1	bacteria					587:594	Gram-negative bacteria	573:594	Gram-negative bacteria	573:594	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	11	27	contain	have	1550:1553	arg1	pathogens					1540:1548	the two pathogens	1532:1548	the two pathogens	1532:1548	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	11	27	contain	have	1550:1553	arg2	degrees					1565:1571	different degrees	1555:1571	different degrees of reduction	1555:1584	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	2	28	theme	prolonged	401:409	arg1	degradation					411:421	prolonged degradation	401:421	prolonged degradation	401:421	It is very important to properly preserve the microbial resources by methods to maintain the purity, viability, and integrity, and to avoid prolonged degradation.					
36126300	12	29	theme	solution	1750:1757	arg1	system					1759:1764	the solution system	1746:1764	the solution system	1746:1764	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	12	29	theme	solution	1750:1757	arg1	beneficial					1776:1785	beneficial	1776:1785	beneficial	1776:1785	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	8	30	theme	0.62 M	1264:1269	arg1	l-carnitine					1271:1281	0.62 M l-carnitine	1264:1281	0.62 M l-carnitine	1264:1281	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	6	31	theme	high	981:984	arg1	concentrations					986:999	high concentrations	981:999	high concentrations of CPAs	981:1007	However, high concentrations of CPAs can produce biochemical toxicity in the two pathogens.					
36126300	11	32	theme	survival	1595:1602	arg1	rate					1604:1607	the survival rate	1591:1607	the survival rate of Y. pestis	1591:1620	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	11	33	theme	freeze-thaw	1512:1522	arg1	cycles					1524:1529	freeze-thaw cycles	1512:1529	freeze-thaw cycles	1512:1529	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	7	34	theme	CPAs	1093:1096	arg1	utilization					1068:1078	The utilization	1064:1078	The utilization of composite CPAs	1064:1096	The utilization of composite CPAs not only reduced the toxicity but also improved the survival rates of samples during cryopreservation.					
36126300	9	35	theme	composite	1317:1325	arg1	l-carnitine					1355:1365	0.62 M l-carnitine	1348:1365	0.62 M l-carnitine	1348:1365	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	9	35	theme	composite	1317:1325	arg1	CPA					1327:1329	The optimal composite CPA	1305:1329	The optimal composite CPA for Y. pestis	1305:1343	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	12	36	theme	nucleation	1726:1735	arg1	sites					1737:1741	uniform nucleation sites	1718:1741	uniform nucleation sites	1718:1741	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	12	37	theme	uniform	1718:1724	arg1	sites					1737:1741	uniform nucleation sites	1718:1741	uniform nucleation sites	1718:1741	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	5	38	theme	Y.	945:946	arg1	rates					915:919	the survival rates	902:919	the survival rates of the N. farcinica and Y. pestis vaccine strains	902:969	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	11	39	theme	pestis	1615:1620	arg1	rate					1604:1607	the survival rate	1591:1607	the survival rate of Y. pestis	1591:1620	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	5	40	theme	vaccine	955:961	arg1	strains					963:969	vaccine strains	955:969	vaccine strains	955:969	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	9	41	theme	0.62 M	1348:1353	arg1	l-carnitine					1355:1365	0.62 M l-carnitine	1348:1365	0.62 M l-carnitine	1348:1365	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	9	41	theme	0.62 M	1348:1353	arg1	CPA					1327:1329	The optimal composite CPA	1305:1329	The optimal composite CPA for Y. pestis	1305:1343	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	12	42	from	distribution	1676:1687	arg1	CPAs					1704:1707	CPAs	1704:1707	CPAs	1704:1707	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	12	43	theme	uniform	1668:1674	arg1	distribution					1676:1687	The uniform distribution	1664:1687	The uniform distribution of bacteria in CPAs	1664:1707	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	1	44	theme	related	175:181	arg1	resources					156:164	valuable biological resources	136:164	valuable biological resources	136:164	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	1	44	theme	related	175:181	arg1	microorganisms					117:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	12	45	theme	differential	1875:1886	arg1	calorimeter					1897:1907	a differential scanning calorimeter	1873:1907	a differential scanning calorimeter	1873:1907	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	4	46	theme	freezing	637:644	arg1	temperature					646:656	freezing temperature	637:656	freezing temperature	637:656	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	11	47	theme	reduction	1576:1584	arg1	degrees					1565:1571	different degrees	1555:1571	different degrees of reduction	1555:1584	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	3	48	theme	pestis	549:554	arg1	technology					478:487	the cryopreservation technology	457:487	the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria)	457:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	5	49	theme	propylene	804:812	arg1	glycol					814:819	propylene glycol	804:819	propylene glycol	804:819	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	49	theme	propylene	804:812	arg1	CPAs					788:791	CPAs	788:791	CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk)	788:877	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	12	50	theme	experimental	1847:1858	arg1	results					1860:1866	the experimental results	1843:1866	the experimental results from a differential scanning calorimeter	1843:1907	The uniform distribution of bacteria in CPAs can form uniform nucleation sites in the solution system, which is beneficial to the cryopreservation of strains, as can be seen from the experimental results from a differential scanning calorimeter.					
36126300	8	51	theme	composite	1213:1221	arg1	CPA					1223:1225	The optimal composite CPA	1201:1225	The optimal composite CPA for N. farcinica	1201:1242	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	8	51	theme	composite	1213:1221	arg1	sucrose					1255:1261	0.292 M sucrose	1247:1261	0.292 M sucrose	1247:1261	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	13	52	theme	pathogenic	2013:2022	arg1	microorganisms					2024:2037	pathogenic microorganisms	2013:2037	pathogenic microorganisms	2013:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	5	53	dep	Y.	945:946	arg1	pestis					948:953	Y. pestis	945:953	Y. pestis	945:953	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	3	54	theme	Gram-negative	573:585	arg1	strains					564:570	vaccine strains	556:570	vaccine strains (Gram-negative bacteria)	556:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	3	54	theme	Gram-negative	573:585	arg1	bacteria					587:594	Gram-negative bacteria	573:594	Gram-negative bacteria	573:594	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	5	55	theme	skim	868:871	arg1	milk					873:876	skim milk	868:876	skim milk	868:876	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	55	theme	skim	868:871	arg1	CPAs					788:791	CPAs	788:791	CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk)	788:877	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	56	dep	farcinica	931:939	arg1	the					924:926	the	924:926	the	924:926	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	5	56	dep	farcinica	931:939	arg1	strains					963:969	vaccine strains	955:969	vaccine strains	955:969	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	13	57	theme	natural	1981:1987	arg1	resources					2000:2008	precious natural biological resources	1972:2008	precious natural biological resources of pathogenic microorganisms	1972:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	8	58	theme	0.292 M	1247:1253	arg1	CPA					1223:1225	The optimal composite CPA	1201:1225	The optimal composite CPA for N. farcinica	1201:1242	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	8	58	theme	0.292 M	1247:1253	arg1	sucrose					1255:1261	0.292 M sucrose	1247:1261	0.292 M sucrose	1247:1261	The optimal composite CPA for N. farcinica is 0.292 M sucrose, 0.62 M l-carnitine, and 2.82 M glycerol.					
36126300	11	59	theme	N.	1650:1651	arg1	farcinica					1653:1661	N. farcinica	1650:1661	N. farcinica	1650:1661	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	7	60	theme	samples	1168:1174	arg1	rates					1159:1163	the survival rates	1146:1163	the survival rates of samples	1146:1174	The utilization of composite CPAs not only reduced the toxicity but also improved the survival rates of samples during cryopreservation.					
36126300	13	61	theme	resources	2000:2008	arg1	preservation					1956:1967	better preservation	1949:1967	better preservation of precious natural biological resources of pathogenic microorganisms	1949:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	1	62	theme	human	199:203	arg1	health					205:210	human health	199:210	human health	199:210	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	1	63	theme	biological	145:154	arg1	resources					156:164	valuable biological resources	136:164	valuable biological resources	136:164	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	1	63	theme	biological	145:154	arg1	microorganisms					117:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms	106:130	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
36126300	4	64	theme	freeze-thaw	663:673	arg1	cycles					675:680	freeze-thaw cycles	663:680	freeze-thaw cycles	663:680	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	7	65	theme	survival	1150:1157	arg1	rates					1159:1163	the survival rates	1146:1163	the survival rates of samples	1146:1174	The utilization of composite CPAs not only reduced the toxicity but also improved the survival rates of samples during cryopreservation.					
36126300	4	66	from	effects	602:608	arg1	bacteria					693:700	the two bacteria	685:700	the two bacteria in the cryopreservation process	685:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	13	67	theme	better	1949:1954	arg1	preservation					1956:1967	better preservation	1949:1967	better preservation of precious natural biological resources of pathogenic microorganisms	1949:2037	This study may provide a reference for better preservation of precious natural biological resources of pathogenic microorganisms.					
36126300	0	68	from	Effect	4:9	arg1	Survival					38:45	the Survival	34:45	the Survival of Nocardia farcinica and Yersinia pestis vaccine strains	34:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	0	69	theme	vaccine	89:95	arg1	strains					97:103	vaccine strains	89:103	vaccine strains	89:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	3	70	theme	present	428:434	arg1	work					436:439	The present work	424:439	The present work	424:439	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	5	71	theme	CPAs	788:791	arg1	addition					776:783	the addition	772:783	the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk)	772:877	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	4	72	theme	cryopreservation	709:724	arg1	process					726:732	the cryopreservation process	705:732	the cryopreservation process	705:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	0	73	theme	Cryopreservation	14:29	arg1	Effect					4:9	The Effect	0:9	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains	0:103	The Effect of Cryopreservation on the Survival of Nocardia farcinica and Yersinia pestis vaccine strains.					
36126300	5	74	theme	survival	906:913	arg1	rates					915:919	the survival rates	902:919	the survival rates of the N. farcinica and Y. pestis vaccine strains	902:969	The results showed that the addition of CPAs (glycerol, propylene glycol, sucrose, glucose, l-carnitine, l-proline, and skim milk) significantly enhanced the survival rates of the N. farcinica and Y. pestis vaccine strains.					
36126300	6	75	theme	CPAs	1004:1007	arg1	concentrations					986:999	high concentrations	981:999	high concentrations of CPAs	981:1007	However, high concentrations of CPAs can produce biochemical toxicity in the two pathogens.					
36126300	7	76	theme	composite	1083:1091	arg1	CPAs					1093:1096	composite CPAs	1083:1096	composite CPAs	1083:1096	The utilization of composite CPAs not only reduced the toxicity but also improved the survival rates of samples during cryopreservation.					
36126300	9	77	theme	optimal	1309:1315	arg1	l-carnitine					1355:1365	0.62 M l-carnitine	1348:1365	0.62 M l-carnitine	1348:1365	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	9	77	theme	optimal	1309:1315	arg1	CPA					1327:1329	The optimal composite CPA	1305:1329	The optimal composite CPA for Y. pestis	1305:1343	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	10	78	theme	strains	1449:1455	arg1	better					1488:1493	better	1488:1493	better	1488:1493	The results showed that the quality of the strains stored at -80°C and -196°C was better.					
36126300	10	78	theme	strains	1449:1455	arg1	quality					1434:1440	the quality	1430:1440	the quality of the strains stored at -80°C and -196°C	1430:1482	The results showed that the quality of the strains stored at -80°C and -196°C was better.					
36126300	11	79	theme	Y.	1612:1613	arg1	pestis					1615:1620	Y. pestis	1612:1620	Y. pestis	1612:1620	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	3	80	theme	cryopreservation	461:476	arg1	technology					478:487	the cryopreservation technology	457:487	the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria)	457:595	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	4	81	from	bacteria	693:700	arg1	process					726:732	the cryopreservation process	705:732	the cryopreservation process	705:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	9	82	theme	Y.	1335:1336	arg1	pestis					1338:1343	Y. pestis	1335:1343	Y. pestis	1335:1343	The optimal composite CPA for Y. pestis is 0.62 M l-carnitine, 8.46 M glycerin, and 0.292 M sucrose.					
36126300	4	83	theme	cryoprotectants	613:627	arg1	effects					602:608	The effects	598:608	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process	598:732	The effects of cryoprotectants (CPAs), freezing temperature, and freeze-thaw cycles on the two bacteria in the cryopreservation process were studied.					
36126300	11	84	theme	different	1555:1563	arg1	degrees					1565:1571	different degrees	1555:1571	different degrees of reduction	1555:1584	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	11	85	theme	cycles	1524:1529	arg1	case					1504:1507	the case	1500:1507	the case of freeze-thaw cycles	1500:1529	For the case of freeze-thaw cycles, the two pathogens have different degrees of reduction, and the survival rate of Y. pestis decreased more than that of N. farcinica.					
36126300	3	86	theme	Gram-positive	512:524	arg1	farcinica					501:509	Nocardia farcinica	492:509	Nocardia farcinica (Gram-positive bacteria)	492:534	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	3	86	theme	Gram-positive	512:524	arg1	bacteria					526:533	Gram-positive bacteria	512:533	Gram-positive bacteria	512:533	The present work aims to explore the cryopreservation technology of Nocardia farcinica (Gram-positive bacteria) and Yersinia pestis vaccine strains (Gram-negative bacteria).					
36126300	1	87	theme	renewable	243:251	arg1	energy					253:258	renewable energy	243:258	renewable energy	243:258	Pathogenic microorganisms are valuable biological resources, closely related to biosecurity, human health, environmental protection, and renewable energy.					
37330980	10	0	theme	Rogosa	1148:1153	arg1	agar					1155:1158	Rogosa agar	1148:1158	Rogosa agar	1148:1158	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	17	1	theme	cavity	1898:1903	arg1	flora					1880:1884	the normal oral flora	1864:1884	the normal oral flora of the oral cavity with probiotics	1864:1919	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	13	2	from	difference	1527:1536	arg1	count					1559:1563	the Lactobacillus count	1541:1563	the Lactobacillus count	1541:1563	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	2	3	theme	normal	249:254	arg1	flora					267:271	the normal intestinal flora	245:271	the normal intestinal flora	245:271	Probiotics maintain the balance of the normal intestinal flora and prevent the proliferation of pathogenic bacteria.					
37330980	7	4	theme	children	819:826	arg1	microflora					758:767	the oral microflora	749:767	the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes	749:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	12	5	theme	significant	1370:1380	arg1	difference					1382:1391	a significant difference	1368:1391	a significant difference compared to the control groups (109 vs. 108 CFU/mL)	1368:1443	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	17	6	theme	oral	1972:1975	arg1	diseases					1977:1984	oral diseases	1972:1984	oral diseases	1972:1984	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	16	7	from	Diabetes	1775:1782	arg1	childhood					1787:1795	childhood	1787:1795	childhood	1787:1795	Diabetes in childhood can affect the composition of the oral flora.					
37330980	1	8	theme	adequate	155:162	arg1	amounts					164:170	adequate amounts	155:170	adequate amounts	155:170	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	8	9	theme	species	950:956	arg1	composition					958:968	its species composition	946:968	its species composition	946:968	Our research also determines the total oral bacterial and Lactobacillus count, and its species composition.					
37330980	12	10	theme	groups	1348:1353	arg1	count					1326:1330	The total bacterial count	1306:1330	The total bacterial count of the two test groups	1306:1353	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	14	11	theme	species	1622:1628	arg1	composition					1630:1640	The species composition	1618:1640	The species composition of the Lactobacillus	1618:1661	The species composition of the Lactobacillus differed in each group.					
37330980	2	12	theme	flora	267:271	arg1	balance					234:240	the balance	230:240	the balance of the normal intestinal flora	230:271	Probiotics maintain the balance of the normal intestinal flora and prevent the proliferation of pathogenic bacteria.					
37330980	1	13	theme	health	181:186	arg1	benefit					188:194	a health benefit	179:194	a health benefit	179:194	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	11	14	used	used	1244:1247	arg2	device					1234:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	12	15	theme	bacterial	1316:1324	arg1	count					1326:1330	The total bacterial count	1306:1330	The total bacterial count of the two test groups	1306:1353	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	17	16	theme	normal	1868:1873	arg1	flora					1880:1884	the normal oral flora	1864:1884	the normal oral flora of the oral cavity with probiotics	1864:1919	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	9	17	theme	0.5	980:982	arg1	ml					984:985	ml	984:985	ml	984:985	METHOD A 0.5 ml saliva sample is collected from the participants (20 participants/group).					
37330980	13	18	theme	significant	1515:1525	arg1	difference					1527:1536	a significant difference	1513:1536	a significant difference in the Lactobacillus count	1513:1563	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	1	19	theme	Live	108:111	arg1	microorganisms					113:126	"Live microorganisms	107:126	"Live microorganisms which when administered in adequate amounts confer a health benefit on the host	107:206	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	1	19	theme	Live	108:111	arg1	probiotics					92:101	probiotics	92:101	probiotics	92:101	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	6	20	theme	normal	634:639	arg1	flora					646:650	the normal oral flora	630:650	the normal oral flora	630:650	Our research investigates how caries and type I diabetes effect the normal oral flora.					
37330980	3	21	theme	therapeutic	331:341	arg1	use					343:345	Its therapeutic use	327:345	Its therapeutic use in oral health	327:360	Its therapeutic use in oral health is increasing.					
37330980	18	22	theme	probiotic	2051:2059	arg1	strains					2061:2067	individual probiotic strains	2040:2067	individual probiotic strains	2040:2067	Further research is needed examining the function of individual probiotic strains.					
37330980	7	23	from	literature	680:689	arg1	topic					699:703	this topic	694:703	this topic	694:703	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	11	24	theme	different	1265:1273	arg1	species					1289:1295	the different Lactobacillus species	1261:1295	the different Lactobacillus species	1261:1295	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	9	25	dep	METHOD	971:976	arg1	sample					994:999	A 0.5 ml saliva sample	978:999	METHOD A 0.5 ml saliva sample	971:999	METHOD A 0.5 ml saliva sample is collected from the participants (20 participants/group).					
37330980	1	26	theme	World	58:62	arg1	Organization					71:82	The World Health Organization	54:82	The World Health Organization	54:82	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	4	27	theme	disease	471:477	arg1	treatment					435:443	the treatment	431:443	the treatment of caries and periodontal disease with probiotics	431:493	The literature reports successful results considering the treatment of caries and periodontal disease with probiotics.					
37330980	4	28	with	treatment	435:443	arg1	probiotics					484:493	probiotics	484:493	probiotics	484:493	The literature reports successful results considering the treatment of caries and periodontal disease with probiotics.					
37330980	0	29	theme	[The	0:3	arg1	role					5:8	[The role	0:8	[The role of probiotics in oral health.	0:38	[The role of probiotics in oral health.]					
37330980	7	30	theme	children	772:779	arg1	microflora					758:767	the oral microflora	749:767	the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes	749:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	11	31	theme	MALDI-TOF	1163:1171	arg1	device					1234:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	15	32	theme	oral	1709:1712	arg1	flora					1714:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora can displace the probiotic strains in the oral cavity.					
37330980	10	33	theme	bacteria	1071:1078	arg1	count					1080:1084	The total bacteria count	1061:1084	The total bacteria count	1061:1084	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	18	34	theme	Further	1987:1993	arg1	research					1995:2002	Further research	1987:2002	Further research	1987:2002	Further research is needed examining the function of individual probiotic strains.					
37330980	15	35	theme	DISCUSSION	1687:1696	arg1	flora					1714:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora can displace the probiotic strains in the oral cavity.					
37330980	16	36	theme	oral	1831:1834	arg1	flora					1836:1840	the oral flora	1827:1840	the oral flora	1827:1840	Diabetes in childhood can affect the composition of the oral flora.					
37330980	13	37	theme	Lactobacillus	1545:1557	arg1	count					1559:1563	the Lactobacillus count	1541:1563	the Lactobacillus count	1541:1563	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	2	38	theme	bacteria	317:324	arg1	proliferation					289:301	the proliferation	285:301	the proliferation of pathogenic bacteria	285:324	Probiotics maintain the balance of the normal intestinal flora and prevent the proliferation of pathogenic bacteria.					
37330980	8	39	theme	total	896:900	arg1	count					935:939	the total oral bacterial and Lactobacillus count	892:939	the total oral bacterial and Lactobacillus count	892:939	Our research also determines the total oral bacterial and Lactobacillus count, and its species composition.					
37330980	11	40	theme	matrix-assisted	1174:1188	arg1	device					1234:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	7	41	with	children	819:826	arg1	diabetes					853:860	those having type 1 diabetes	833:860	those having type 1 diabetes	833:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	8	42	theme	bacterial	907:915	arg1	count					935:939	the total oral bacterial and Lactobacillus count	892:939	the total oral bacterial and Lactobacillus count	892:939	Our research also determines the total oral bacterial and Lactobacillus count, and its species composition.					
37330980	17	43	with	flora	1880:1884	arg1	probiotics					1910:1919	probiotics	1910:1919	probiotics	1910:1919	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	12	44	theme	control	1409:1415	arg1	CFU/mL					1437:1442	109 vs. 108 CFU/mL	1425:1442	109 vs. 108 CFU/mL	1425:1442	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	12	44	theme	control	1409:1415	arg1	groups					1417:1422	the control groups	1405:1422	the control groups (109 vs. 108 CFU/mL)	1405:1443	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	8	45	theme	Lactobacillus	921:933	arg1	count					935:939	the total oral bacterial and Lactobacillus count	892:939	the total oral bacterial and Lactobacillus count	892:939	Our research also determines the total oral bacterial and Lactobacillus count, and its species composition.					
37330980	10	46	theme	blood	1103:1107	arg1	Lactobacillus					1119:1131	the Lactobacillus	1115:1131	the Lactobacillus is cultured on Rogosa agar	1115:1158	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	10	46	theme	blood	1103:1107	arg1	agar					1109:1112	blood agar	1103:1112	blood agar	1103:1112	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	15	47	theme	oral	1762:1765	arg1	cavity					1767:1772	the oral cavity	1758:1772	the oral cavity	1758:1772	DISCUSSION Cariogenic oral flora can displace the probiotic strains in the oral cavity.					
37330980	11	48	theme	desorption/ionization-time-of-flight	1196:1231	arg1	device					1234:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	14	49	theme	Lactobacillus	1649:1661	arg1	composition					1630:1640	The species composition	1618:1640	The species composition of the Lactobacillus	1618:1661	The species composition of the Lactobacillus differed in each group.					
37330980	17	50	theme	oral	1893:1896	arg1	cavity					1898:1903	the oral cavity	1889:1903	the oral cavity	1889:1903	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	2	51	theme	intestinal	256:265	arg1	flora					267:271	the normal intestinal flora	245:271	the normal intestinal flora	245:271	Probiotics maintain the balance of the normal intestinal flora and prevent the proliferation of pathogenic bacteria.					
37330980	7	52	theme	having	839:844	arg1	diabetes					853:860	those having type 1 diabetes	833:860	those having type 1 diabetes	833:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	15	53	theme	probiotic	1737:1745	arg1	strains					1747:1753	the probiotic strains	1733:1753	the probiotic strains	1733:1753	DISCUSSION Cariogenic oral flora can displace the probiotic strains in the oral cavity.					
37330980	17	54	theme	diseases	1977:1984	arg1	development					1957:1967	the development	1953:1967	the development of oral diseases	1953:1984	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	7	55	theme	healthy	811:817	arg1	children					819:826	healthy children	811:826	healthy children with those having type 1 diabetes	811:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	20	56	dep	942-947	2096:2102	arg1	2023					2081:2084	2023	2081:2084	2023	2081:2084	2023; 164(24): 942-947.					
37330980	12	57	theme	test	1343:1346	arg1	groups					1348:1353	the two test groups	1335:1353	the two test groups	1335:1353	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	4	58	theme	caries	448:453	arg1	treatment					435:443	the treatment	431:443	the treatment of caries and periodontal disease with probiotics	431:493	The literature reports successful results considering the treatment of caries and periodontal disease with probiotics.					
37330980	12	59	theme	total	1310:1314	arg1	count					1326:1330	The total bacterial count	1306:1330	The total bacterial count of the two test groups	1306:1353	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	3	60	from	use	343:345	arg1	health					355:360	oral health	350:360	oral health	350:360	Its therapeutic use in oral health is increasing.					
37330980	5	61	theme	oral	534:537	arg1	flora					539:543	the oral flora	530:543	the oral flora causing the disease	530:563	In these cases, probiotics effect the oral flora causing the disease.					
37330980	17	62	theme	oral	1875:1878	arg1	flora					1880:1884	the normal oral flora	1864:1884	the normal oral flora of the oral cavity with probiotics	1864:1919	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	4	63	theme	successful	400:409	arg1	results					411:417	successful results	400:417	successful results	400:417	The literature reports successful results considering the treatment of caries and periodontal disease with probiotics.					
37330980	17	64	theme	possible	1926:1933	arg1	way					1935:1937	a possible way	1924:1937	a possible way of preventing the development of oral diseases	1924:1984	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	17	64	theme	possible	1926:1933	arg1	CONCLUSION					1843:1852	CONCLUSION	1843:1852	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics	1843:1919	CONCLUSION Restoring the normal oral flora of the oral cavity with probiotics is a possible way of preventing the development of oral diseases.					
37330980	6	65	theme	oral	641:644	arg1	flora					646:650	the normal oral flora	630:650	the normal oral flora	630:650	Our research investigates how caries and type I diabetes effect the normal oral flora.					
37330980	18	66	theme	individual	2040:2049	arg1	strains					2061:2067	individual probiotic strains	2040:2067	individual probiotic strains	2040:2067	Further research is needed examining the function of individual probiotic strains.					
37330980	1	67	dep	INTRODUCTION	41:52	arg1	defines					84:90	defines	84:90	defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host	84:206	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	9	68	theme	ml	984:985	arg1	sample					994:999	A 0.5 ml saliva sample	978:999	METHOD A 0.5 ml saliva sample	971:999	METHOD A 0.5 ml saliva sample is collected from the participants (20 participants/group).					
37330980	13	69	with	children	1463:1470	arg1	caries					1477:1482	caries	1477:1482	caries	1477:1482	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	13	69	with	children	1463:1470	arg1	diabetes					1493:1500	diabetes	1493:1500	diabetes	1493:1500	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	13	70	theme	children	1463:1470	arg1	children					1463:1470	children	1463:1470	children with caries and with diabetes	1463:1500	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	13	70	theme	children	1463:1470	arg1	groups					1453:1458	the groups	1449:1458	the groups of children with caries and with diabetes	1449:1500	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	9	71	theme	saliva	987:992	arg1	sample					994:999	A 0.5 ml saliva sample	978:999	METHOD A 0.5 ml saliva sample	971:999	METHOD A 0.5 ml saliva sample is collected from the participants (20 participants/group).					
37330980	0	72	from	role	5:8	arg1	health					32:37	oral health	27:37	oral health	27:37	[The role of probiotics in oral health.]					
37330980	6	73	theme	type	607:610	arg1	diabetes					614:621	type I diabetes	607:621	type I diabetes	607:621	Our research investigates how caries and type I diabetes effect the normal oral flora.					
37330980	18	74	theme	strains	2061:2067	arg1	function					2028:2035	the function	2024:2035	the function of individual probiotic strains	2024:2067	Further research is needed examining the function of individual probiotic strains.					
37330980	4	75	theme	periodontal	459:469	arg1	disease					471:477	periodontal disease	459:477	periodontal disease	459:477	The literature reports successful results considering the treatment of caries and periodontal disease with probiotics.					
37330980	11	76	theme	Lactobacillus	1275:1287	arg1	species					1289:1295	the different Lactobacillus species	1261:1295	the different Lactobacillus species	1261:1295	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	12	77	dep	RESULTS	1298:1304	arg1	show					1363:1366	show	1363:1366	did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL)	1355:1443	RESULTS The total bacterial count of the two test groups did not show a significant difference compared to the control groups (109 vs. 108 CFU/mL).					
37330980	1	78	theme	Health	64:69	arg1	Organization					71:82	The World Health Organization	54:82	The World Health Organization	54:82	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	15	79	theme	Cariogenic	1698:1707	arg1	flora					1714:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora	1687:1718	DISCUSSION Cariogenic oral flora can displace the probiotic strains in the oral cavity.					
37330980	0	80	theme	probiotics	13:22	arg1	role					5:8	[The role	0:8	[The role of probiotics in oral health.	0:38	[The role of probiotics in oral health.]					
37330980	3	81	theme	oral	350:353	arg1	health					355:360	oral health	350:360	oral health	350:360	Its therapeutic use in oral health is increasing.					
37330980	13	82	theme	control	1581:1587	arg1	CFU/mL					1609:1614	102 vs. 103 CFU/mL	1597:1614	102 vs. 103 CFU/mL	1597:1614	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	13	82	theme	control	1581:1587	arg1	groups					1589:1594	the control groups	1577:1594	the control groups (102 vs. 103 CFU/mL)	1577:1615	In the groups of children with caries and with diabetes, there was a significant difference in the Lactobacillus count compared to the control groups (102 vs. 103 CFU/mL).					
37330980	0	83	theme	oral	27:30	arg1	health					32:37	oral health	27:37	oral health	27:37	[The role of probiotics in oral health.]					
37330980	10	84	theme	total	1065:1069	arg1	count					1080:1084	The total bacteria count	1061:1084	The total bacteria count	1061:1084	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	16	85	theme	flora	1836:1840	arg1	composition					1812:1822	the composition	1808:1822	the composition of the oral flora	1808:1840	Diabetes in childhood can affect the composition of the oral flora.					
37330980	1	86	dep	confer	172:177	arg1	microorganisms					113:126	"Live microorganisms	107:126	"Live microorganisms which when administered in adequate amounts confer a health benefit on the host	107:206	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	1	86	dep	confer	172:177	arg1	probiotics					92:101	probiotics	92:101	probiotics	92:101	INTRODUCTION The World Health Organization defines probiotics as: "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."					
37330980	7	87	theme	oral	753:756	arg1	microflora					758:767	the oral microflora	749:767	the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes	749:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
37330980	2	88	theme	pathogenic	306:315	arg1	bacteria					317:324	pathogenic bacteria	306:324	pathogenic bacteria	306:324	Probiotics maintain the balance of the normal intestinal flora and prevent the proliferation of pathogenic bacteria.					
37330980	11	89	theme	laser	1190:1194	arg1	device					1234:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device	1161:1239	A MALDI-TOF (matrix-assisted laser desorption/ionization-time-of-flight) device is used to identify the different Lactobacillus species.					
37330980	10	90	dep	Lactobacillus	1119:1131	arg1	cultured					1136:1143	cultured	1136:1143	is cultured on Rogosa agar	1133:1158	The total bacteria count is determined on blood agar, the Lactobacillus is cultured on Rogosa agar.					
37330980	8	91	theme	oral	902:905	arg1	count					935:939	the total oral bacterial and Lactobacillus count	892:939	the total oral bacterial and Lactobacillus count	892:939	Our research also determines the total oral bacterial and Lactobacillus count, and its species composition.					
37330980	7	92	theme	type	846:849	arg1	diabetes					853:860	those having type 1 diabetes	833:860	those having type 1 diabetes	833:860	OBJECTIVE To summarize the literature on this topic and to present our research, which compares the oral microflora of children with or without caries and of healthy children with those having type 1 diabetes.					
36921831	1	0	theme	group	361:365	arg1	source					367:372	an isocyanate group source	347:372	an isocyanate group source	347:372	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	0	theme	group	361:365	arg1	trimer					324:329	hexamethylene diisocyanate trimer	297:329	hexamethylene diisocyanate trimer	297:329	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	0	1	theme	isocyanate	169:178	arg1	groups					180:185	isocyanate groups	169:185	isocyanate groups used	169:190	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	4	2	theme	%	757:757	arg1	%					751:751	7.5 %	747:751	7.5 % (50 % MCC)	747:762	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	2	theme	%	757:757	arg1	MCC					759:761	50 % MCC	754:761	50 % MCC	754:761	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	2	theme	%	757:757	arg1	CNC					767:769	CNC	767:769	CNC dispersed in the reaction medium	767:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	0	3	theme	cellulose	77:85	arg1	nanocrystals					87:98	cellulose nanocrystals	77:98	cellulose nanocrystals	77:98	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	9	4	theme	reported	1173:1180	arg1	unprecedented					1218:1230	unprecedented	1218:1230	unprecedented	1218:1230	The reported results, as far as it is known, are unprecedented.					
36921831	9	4	theme	reported	1173:1180	arg1	results					1182:1188	The reported results	1169:1188	The reported results	1169:1188	The reported results, as far as it is known, are unprecedented.					
36921831	4	5	theme	50 	754:756	arg1	%					751:751	7.5 %	747:751	7.5 % (50 % MCC)	747:762	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	5	theme	50 	754:756	arg1	MCC					759:761	50 % MCC	754:761	50 % MCC	754:761	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	5	theme	50 	754:756	arg1	CNC					767:769	CNC	767:769	CNC dispersed in the reaction medium	767:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	1	6	theme	high	432:435	arg1	contents					437:444	high contents	432:444	high contents of microcrystalline cellulose (MCC, polyol)	432:488	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	7	dep	cellulose	466:474	arg1	polyol					482:487	polyol	482:487	polyol	482:487	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	7	dep	cellulose	466:474	arg1	MCC					477:479	MCC	477:479	MCC	477:479	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	4	8	theme	stiffer	817:823	arg1	films					811:815	films	811:815	films stiffer than their counterparts	811:847	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	1	9	theme	bio-based	272:280	arg1	polyurethanes					282:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	0	10	theme	groups	180:185	arg1	source					159:164	the source	155:164	the source of isocyanate groups used	155:190	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	9	11	dep	results	1182:1188	arg1	known					1207:1211	known	1207:1211	is known	1204:1211	The reported results, as far as it is known, are unprecedented.					
36921831	6	12	theme	hydrophobic	958:968	arg1	surfaces					975:982	hydrophobic film surfaces	958:982	hydrophobic film surfaces	958:982	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	3	13	dep	80 	582:584	arg1	to					579:580	to	579:580	to	579:580	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	2	14	theme	Castor	524:529	arg1	oil					531:533	Castor oil	524:533	Castor oil	524:533	Castor oil was used as an additional polyol source.					
36921831	2	14	theme	Castor	524:529	arg1	source					568:573	an additional polyol source	547:573	an additional polyol source	547:573	Castor oil was used as an additional polyol source.					
36921831	0	15	from	cellulose	51:59	arg1	formation					19:27	formation	19:27	formation from microcrystalline cellulose	19:59	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	1	16	theme	reaction	401:408	arg1	medium					410:415	a low-viscosity reaction medium	385:415	a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC)	385:521	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	3	17	theme	Young	696:700	arg1	522.4 MPa					713:721	522.4 MPa	713:721	522.4 MPa	713:721	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	3	17	theme	Young	696:700	arg1	modulus					704:710	Young's modulus	696:710	Young's modulus (522.4 MPa)	696:722	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	3	18	theme	highest	645:651	arg1	72 °C					657:661	72 °C	657:661	72 °C	657:661	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	3	18	theme	highest	645:651	arg1	Tg					653:654	the highest Tg	641:654	the highest Tg (72 °C)	641:662	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	1	19	theme	cellulose	494:502	arg1	CNC					518:520	CNC	518:520	CNC	518:520	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	19	theme	cellulose	494:502	arg1	nanocrystals					504:515	cellulose nanocrystals	494:515	cellulose nanocrystals (CNC)	494:521	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	8	20	theme	cell	1130:1133	arg1	growth					1135:1140	cell growth	1130:1140	cell growth	1130:1140	The films were non-cytotoxic, and the composites exhibited cell growth compared with the control.					
36921831	1	21	theme	hexamethylene	297:309	arg1	source					367:372	an isocyanate group source	347:372	an isocyanate group source	347:372	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	21	theme	hexamethylene	297:309	arg1	trimer					324:329	hexamethylene diisocyanate trimer	297:329	hexamethylene diisocyanate trimer	297:329	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	2	22	theme	polyol	561:566	arg1	oil					531:533	Castor oil	524:533	Castor oil	524:533	Castor oil was used as an additional polyol source.					
36921831	2	22	theme	polyol	561:566	arg1	source					568:573	an additional polyol source	547:573	an additional polyol source	547:573	Castor oil was used as an additional polyol source.					
36921831	5	23	theme	high	891:894	arg1	crystallinity					896:908	high crystallinity	891:908	high crystallinity	891:908	All the films exhibited transparency and high crystallinity.					
36921831	7	24	theme	physiological	1039:1051	arg1	fluids					1053:1058	physiological fluids	1039:1058	physiological fluids	1039:1058	At pH 7.4, ζ suggested that the films interacted with physiological fluids favorably.					
36921831	1	25	theme	diisocyanate	311:322	arg1	source					367:372	an isocyanate group source	347:372	an isocyanate group source	347:372	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	25	theme	diisocyanate	311:322	arg1	trimer					324:329	hexamethylene diisocyanate trimer	297:329	hexamethylene diisocyanate trimer	297:329	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	2	26	theme	additional	550:559	arg1	oil					531:533	Castor oil	524:533	Castor oil	524:533	Castor oil was used as an additional polyol source.					
36921831	2	26	theme	additional	550:559	arg1	source					568:573	an additional polyol source	547:573	an additional polyol source	547:573	Castor oil was used as an additional polyol source.					
36921831	6	27	theme	film	970:973	arg1	surfaces					975:982	hydrophobic film surfaces	958:982	hydrophobic film surfaces	958:982	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	0	28	theme	low	138:140	arg1	viscosity					142:150	the low viscosity	134:150	the low viscosity of the source of isocyanate groups used	134:190	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	4	29	theme	%	736:736	arg1	%					730:730	12.5 %	725:730	12.5 % (30 % MCC)	725:741	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	29	theme	%	736:736	arg1	MCC					738:740	30 % MCC	733:740	30 % MCC	733:740	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	29	theme	%	736:736	arg1	CNC					767:769	CNC	767:769	CNC dispersed in the reaction medium	767:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	6	30	theme	angle/zeta	923:932	arg1	potential					934:942	The contact angle/zeta potential	911:942	The contact angle/zeta potential (ζ)	911:946	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	6	30	theme	angle/zeta	923:932	arg1	ζ					945:945	ζ	945:945	ζ	945:945	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	0	31	theme	microcrystalline	34:49	arg1	cellulose					51:59	microcrystalline cellulose	34:59	microcrystalline cellulose	34:59	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	1	32	theme	catalyst-free	258:270	arg1	polyurethanes					282:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	4	33	theme	30 	733:735	arg1	%					730:730	12.5 %	725:730	12.5 % (30 % MCC)	725:741	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	33	theme	30 	733:735	arg1	MCC					738:740	30 % MCC	733:740	30 % MCC	733:740	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	33	theme	30 	733:735	arg1	CNC					767:769	CNC	767:769	CNC dispersed in the reaction medium	767:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	6	34	theme	contact	915:921	arg1	potential					934:942	The contact angle/zeta potential	911:942	The contact angle/zeta potential (ζ)	911:946	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	6	34	theme	contact	915:921	arg1	ζ					945:945	ζ	945:945	ζ	945:945	The contact angle/zeta potential (ζ) indicated hydrophobic film surfaces.					
36921831	4	35	theme	CNC	767:769	arg1	%					730:730	12.5 %	725:730	12.5 % (30 % MCC)	725:741	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	35	theme	CNC	767:769	arg1	%					751:751	7.5 %	747:751	7.5 % (50 % MCC)	747:762	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	35	theme	CNC	767:769	arg1	MCC					759:761	50 % MCC	754:761	50 % MCC	754:761	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	35	theme	CNC	767:769	arg1	MCC					738:740	30 % MCC	733:740	30 % MCC	733:740	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	4	35	theme	CNC	767:769	arg1	CNC					767:769	CNC	767:769	CNC dispersed in the reaction medium	767:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	2	36	used	used	539:542	arg2	oil					531:533	Castor oil	524:533	Castor oil	524:533	Castor oil was used as an additional polyol source.					
36921831	2	36	used	used	539:542	arg2	source					568:573	an additional polyol source	547:573	an additional polyol source	547:573	Castor oil was used as an additional polyol source.					
36921831	1	37	theme	low-viscosity	387:399	arg1	medium					410:415	a low-viscosity reaction medium	385:415	a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC)	385:521	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	4	38	theme	reaction	788:795	arg1	medium					797:802	the reaction medium	784:802	the reaction medium	784:802	12.5 % (30 % MCC) and 7.5 % (50 % MCC) of CNC dispersed in the reaction medium formed films stiffer than their counterparts.					
36921831	0	39	theme	source	159:164	arg1	viscosity					142:150	the low viscosity	134:150	the low viscosity of the source of isocyanate groups used	134:190	Polyurethane films formation from microcrystalline cellulose as a polyol and cellulose nanocrystals as additive: Reactions favored by the low viscosity of the source of isocyanate groups used.					
36921831	1	40	theme	microcrystalline	449:464	arg1	cellulose					466:474	microcrystalline cellulose	449:474	microcrystalline cellulose (MCC, polyol)	449:488	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	41	theme	cellulose	466:474	arg1	CNC					518:520	CNC	518:520	CNC	518:520	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	41	theme	cellulose	466:474	arg1	contents					437:444	high contents	432:444	high contents of microcrystalline cellulose (MCC, polyol)	432:488	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	41	theme	cellulose	466:474	arg1	nanocrystals					504:515	cellulose nanocrystals	494:515	cellulose nanocrystals (CNC)	494:521	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	3	42	theme	MCC	594:596	arg1	%					585:585	Up to 80 %	576:585	Up to 80 % of the MCC	576:596	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	3	42	theme	MCC	594:596	arg1	MCC					594:596	the MCC	590:596	the MCC	590:596	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	1	43	theme	isocyanate	350:359	arg1	source					367:372	an isocyanate group source	347:372	an isocyanate group source	347:372	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	1	43	theme	isocyanate	350:359	arg1	trimer					324:329	hexamethylene diisocyanate trimer	297:329	hexamethylene diisocyanate trimer	297:329	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36921831	3	44	theme	tensile	665:671	arg1	18 MPa					683:688	18 MPa	683:688	18 MPa	683:688	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	3	44	theme	tensile	665:671	arg1	strength					673:680	tensile strength	665:680	tensile strength (18 MPa)	665:689	Up to 80 % of the MCC was dispersed, producing a film exhibiting the highest Tg (72 °C), tensile strength (18 MPa), and Young's modulus (522.4 MPa).					
36921831	1	45	theme	solvent-free	241:252	arg1	polyurethanes					282:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	solvent-free and catalyst-free bio-based polyurethanes	241:294	To simultaneously form films while synthesizing solvent-free and catalyst-free bio-based polyurethanes, hexamethylene diisocyanate trimer was selected as an isocyanate group source to produce a low-viscosity reaction medium for dispersing high contents of microcrystalline cellulose (MCC, polyol) and cellulose nanocrystals (CNC).					
36413260	7	0	theme	bond	1458:1461	arg1	basicity					1463:1470	hydrogen bond basicity	1449:1470	hydrogen bond basicity determined by solvatochromic and magnetic methods	1449:1520	However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends.					
36413260	8	1	theme	probes	1621:1626	arg1	shift					1596:1600	the chemical shift	1583:1600	the chemical shift of solvatomagnetic probes	1583:1626	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	9	2	theme	mixing	2087:2092	arg1	absence					2076:2082	the absence	2072:2082	the absence of mixing	2072:2092	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	6	3	theme	water	1248:1252	arg1	content					1254:1260	water content	1248:1260	water content	1248:1260	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	6	4	theme	chloride-urea	1416:1428	arg1	mixtures					1430:1437	aqueous choline chloride-urea mixtures	1400:1437	aqueous choline chloride-urea mixtures	1400:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	3	5	theme	molar	686:690	arg1	ratio					692:696	the molar ratio	682:696	the molar ratio of compounds	682:709	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	4	6	theme	solvatochromic	791:804	arg1	parameters					834:843	solvatochromic and solvatomagnetic solvent parameters	791:843	solvatochromic and solvatomagnetic solvent parameters	791:843	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	7	theme	solvatomagnetic	810:824	arg1	parameters					834:843	solvatochromic and solvatomagnetic solvent parameters	791:843	solvatochromic and solvatomagnetic solvent parameters	791:843	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	6	8	theme	mixtures	1212:1219	arg1	values					1194:1199	Hydrogen bond acceptor values	1171:1199	Hydrogen bond acceptor values of aqueous mixtures	1171:1219	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	3	9	theme	DES	550:552	arg1	nanostructure					533:545	the nanostructure	529:545	the nanostructure of DES	529:552	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	4	10	theme	chloride	885:892	arg1	capacity					865:872	fiber swelling capacity	850:872	fiber swelling capacity	850:872	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	10	theme	chloride	885:892	arg1	parameters					834:843	solvatochromic and solvatomagnetic solvent parameters	791:843	solvatochromic and solvatomagnetic solvent parameters	791:843	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	10	theme	chloride	885:892	arg1	pH					773:774	pH	773:774	pH	773:774	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	10	theme	chloride	885:892	arg1	viscosity					762:770	viscosity	762:770	viscosity	762:770	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	10	theme	chloride	885:892	arg1	conductivity					777:788	conductivity	777:788	conductivity	777:788	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	9	11	theme	choline	1901:1907	arg1	mixture					1923:1929	the choline chloride-urea mixture	1897:1929	the choline chloride-urea mixture	1897:1929	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	12	theme	appealing	2140:2148	arg1	systems					2150:2156	appealing systems	2140:2156	appealing systems for cellulose pretreatments	2140:2184	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	3	13	theme	nanostructure	533:545	arg1	formation					516:524	the formation	512:524	the formation of the nanostructure of DES	512:552	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	1	14	theme	deep	186:189	arg1	mixtures					173:180	Eutectic mixtures	164:180	Eutectic mixtures	164:180	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	14	theme	deep	186:189	arg1	media					236:240	green media	230:240	green media	230:240	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	14	theme	deep	186:189	arg1	DESs					210:213	DESs	210:213	DESs	210:213	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	14	theme	deep	186:189	arg1	solvents					200:207	deep eutectic solvents	186:207	deep eutectic solvents (DESs)	186:214	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	4	15	theme	urea	898:901	arg1	mixtures					903:910	urea mixtures	898:910	urea mixtures demonstrating different molar ratios	898:947	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	6	16	theme	aqueous	1204:1210	arg1	mixtures					1212:1219	aqueous mixtures	1204:1219	aqueous mixtures	1204:1219	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	9	17	theme	mixture	1923:1929	arg1	non-ideality					1881:1892	the non-ideality	1877:1892	the non-ideality of the choline chloride-urea mixture	1877:1929	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	17	theme	mixture	1923:1929	arg1	absence					1939:1945	the absence	1935:1945	the absence of water	1935:1954	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	17	theme	mixture	1923:1929	arg1	advantageous					1973:1984	advantageous	1973:1984	advantageous	1973:1984	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	3	18	theme	point	737:741	arg1	composition					743:753	the eutectic point composition	724:753	the eutectic point composition	724:753	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	0	19	theme	eutectic	107:114	arg1	mixtures					116:123	urea-based eutectic mixtures	96:123	urea-based eutectic mixtures	96:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	8	20	theme	water	1741:1745	arg1	content					1747:1753	the water content	1737:1753	the water content of 30 wt%	1737:1763	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	4	21	theme	swelling	856:863	arg1	capacity					865:872	fiber swelling capacity	850:872	fiber swelling capacity	850:872	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	8	22	dep	chloride-urea	1683:1695	arg1	1 					1698:1699	1 	1698:1699	1 : 2	1698:1702	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	6	23	theme	bond	1180:1183	arg1	acceptor					1185:1192	Hydrogen bond acceptor	1171:1192	Hydrogen bond acceptor values of aqueous mixtures	1171:1219	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	0	24	theme	cellulose	135:143	arg1	capacity					154:161	their cellulose swelling capacity	129:161	their cellulose swelling capacity	129:161	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	8	25	theme	wt	1761:1762	arg1	%					1763:1763	30 wt%	1758:1763	30 wt%	1758:1763	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	8	26	theme	chloride-urea	1683:1695	arg1	mixture					1705:1711	the choline chloride-urea (1 : 2) mixture	1671:1711	the choline chloride-urea (1 : 2) mixture	1671:1711	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	5	27	with	clusters	1068:1075	arg1	urea					1103:1106	urea	1103:1106	urea	1103:1106	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	5	27	with	clusters	1068:1075	arg1	chloride					1090:1097	choline chloride	1082:1097	choline chloride	1082:1097	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	0	28	theme	added	42:46	arg1	water					48:52	added water	42:52	added water	42:52	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	5	29	from	participation	1015:1027	arg1	formation					1045:1053	the formation	1041:1053	the formation of molecular clusters with choline chloride and urea	1041:1106	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	5	30	theme	molecular	1058:1066	arg1	clusters					1068:1075	molecular clusters	1058:1075	molecular clusters with choline chloride and urea	1058:1106	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	8	31	theme	previous	1782:1789	arg1	simulations					1801:1811	previous molecular simulations	1782:1811	previous molecular simulations	1782:1811	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	7	32	theme	opposite	1539:1546	arg1	trends					1548:1553	almost opposite trends	1532:1553	almost opposite trends	1532:1553	However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends.					
36413260	4	33	theme	molar	936:940	arg1	ratios					942:947	different molar ratios	926:947	different molar ratios	926:947	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	0	34	theme	choline	75:81	arg1	chloride					83:90	choline chloride	75:90	choline chloride	75:90	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	0	35	theme	molar	26:30	arg1	ratio					32:36	molar ratio	26:36	molar ratio	26:36	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	4	36	theme	added	998:1002	arg1	water					1004:1008	added water	998:1008	added water	998:1008	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	5	37	theme	conductivity	1144:1155	arg1	measurements					1157:1168	conductivity measurements	1144:1168	conductivity measurements	1144:1168	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	9	38	theme	aqueous	1996:2002	arg1	mixtures					2004:2011	aqueous mixtures	1996:2011	aqueous mixtures	1996:2011	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	2	39	dep	cellulose-based	424:438	arg1	nano					441:444	nano	441:444	nano	441:444	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	8	40	dep	1 	1698:1699	arg1	 2					1701:1702	 2	1701:1702	1 : 2	1698:1702	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	6	41	theme	bond	1384:1387	arg1	acidity					1389:1395	hydrogen bond acidity	1375:1395	hydrogen bond acidity of aqueous choline chloride-urea mixtures	1375:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	0	42	from	capacity	154:161	arg1	properties					61:70	the properties	57:70	the properties of choline chloride and urea-based eutectic mixtures	57:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	3	43	theme	many	616:619	arg1	properties					631:640	many important properties	616:640	many important properties	616:640	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	1	44	theme	materials	282:290	arg1	pre-treatment					250:262	the pre-treatment	246:262	the pre-treatment of lignocellulose materials	246:290	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	0	45	theme	ratio	32:36	arg1	capacity					154:161	their cellulose swelling capacity	129:161	their cellulose swelling capacity	129:161	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	0	45	theme	ratio	32:36	arg1	role					18:21	the role	14:21	the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures	14:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	9	46	theme	cellulose	1819:1827	arg1	fibers					1829:1834	cellulose fibers	1819:1834	cellulose fibers	1819:1834	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	47	theme	fibers	2062:2067	arg1	diameters					2039:2047	the diameters	2035:2047	the diameters of cellulose fibers	2035:2067	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	3	48	theme	Several	458:464	arg1	studies					466:472	Several studies	458:472	Several studies	458:472	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	7	49	theme	hydrogen	1449:1456	arg1	basicity					1463:1470	hydrogen bond basicity	1449:1470	hydrogen bond basicity determined by solvatochromic and magnetic methods	1449:1520	However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends.					
36413260	8	50	theme	shift	1596:1600	arg1	investigation					1566:1578	The close investigation	1556:1578	The close investigation of the chemical shift of solvatomagnetic probes	1556:1626	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	8	51	with	line	1772:1775	arg1	simulations					1801:1811	previous molecular simulations	1782:1811	previous molecular simulations	1782:1811	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	6	52	theme	content	1254:1260	arg1	function					1236:1243	a function	1234:1243	a function of water content	1234:1260	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	6	53	theme	mixtures	1430:1437	arg1	acidity					1389:1395	hydrogen bond acidity	1375:1395	hydrogen bond acidity of aqueous choline chloride-urea mixtures	1375:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	4	54	theme	solvent	826:832	arg1	parameters					834:843	solvatochromic and solvatomagnetic solvent parameters	791:843	solvatochromic and solvatomagnetic solvent parameters	791:843	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	8	55	theme	solvatomagnetic	1605:1619	arg1	probes					1621:1626	solvatomagnetic probes	1605:1626	solvatomagnetic probes	1605:1626	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	3	56	theme	DES	661:663	arg1	properties					631:640	many important properties	616:640	many important properties	616:640	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	4	57	dep	presence	974:981	arg1	the					970:972	the	970:972	the	970:972	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	6	58	theme	choline	1408:1414	arg1	mixtures					1430:1437	aqueous choline chloride-urea mixtures	1400:1437	aqueous choline chloride-urea mixtures	1400:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	9	59	theme	water-containing	2099:2114	arg1	mixtures					2116:2123	water-containing mixtures	2099:2123	water-containing mixtures	2099:2123	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	1	60	theme	Eutectic	164:171	arg1	mixtures					173:180	Eutectic mixtures	164:180	Eutectic mixtures	164:180	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	60	theme	Eutectic	164:171	arg1	media					236:240	green media	230:240	green media	230:240	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	60	theme	Eutectic	164:171	arg1	solvents					200:207	deep eutectic solvents	186:207	deep eutectic solvents (DESs)	186:214	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	0	61	theme	urea-based	96:105	arg1	mixtures					116:123	urea-based eutectic mixtures	96:123	urea-based eutectic mixtures	96:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	8	62	theme	mixture	1705:1711	arg1	environment					1656:1666	the chemical environment	1643:1666	the chemical environment of the choline chloride-urea (1 : 2) mixture	1643:1711	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	4	63	theme	choline	877:883	arg1	chloride					885:892	choline chloride	877:892	choline chloride	877:892	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	9	64	theme	chloride-urea	1909:1921	arg1	mixture					1923:1929	the choline chloride-urea mixture	1897:1929	the choline chloride-urea mixture	1897:1929	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	3	65	theme	compounds	701:709	arg1	ratio					692:696	the molar ratio	682:696	the molar ratio of compounds	682:709	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	0	66	theme	mixtures	116:123	arg1	properties					61:70	the properties	57:70	the properties of choline chloride and urea-based eutectic mixtures	57:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	1	67	theme	eutectic	191:198	arg1	mixtures					173:180	Eutectic mixtures	164:180	Eutectic mixtures	164:180	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	67	theme	eutectic	191:198	arg1	media					236:240	green media	230:240	green media	230:240	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	67	theme	eutectic	191:198	arg1	DESs					210:213	DESs	210:213	DESs	210:213	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	67	theme	eutectic	191:198	arg1	solvents					200:207	deep eutectic solvents	186:207	deep eutectic solvents (DESs)	186:214	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	9	68	theme	cellulose	2162:2170	arg1	pretreatments					2172:2184	cellulose pretreatments	2162:2184	cellulose pretreatments	2162:2184	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	4	69	theme	fiber	850:854	arg1	capacity					865:872	fiber swelling capacity	850:872	fiber swelling capacity	850:872	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	6	70	theme	acceptor	1185:1192	arg1	values					1194:1199	Hydrogen bond acceptor values	1171:1199	Hydrogen bond acceptor values of aqueous mixtures	1171:1219	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	3	71	theme	eutectic	728:735	arg1	composition					743:753	the eutectic point composition	724:753	the eutectic point composition	724:753	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	0	72	theme	swelling	145:152	arg1	capacity					154:161	their cellulose swelling capacity	129:161	their cellulose swelling capacity	129:161	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	1	73	dep	promising	220:228	arg1	mixtures					173:180	Eutectic mixtures	164:180	Eutectic mixtures	164:180	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	73	dep	promising	220:228	arg1	media					236:240	green media	230:240	green media	230:240	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	1	73	dep	promising	220:228	arg1	solvents					200:207	deep eutectic solvents	186:207	deep eutectic solvents (DESs)	186:214	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	6	74	theme	Hydrogen	1171:1178	arg1	acceptor					1185:1192	Hydrogen bond acceptor	1171:1192	Hydrogen bond acceptor values of aqueous mixtures	1171:1219	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	9	75	theme	water	1950:1954	arg1	non-ideality					1881:1892	the non-ideality	1877:1892	the non-ideality of the choline chloride-urea mixture	1877:1929	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	75	theme	water	1950:1954	arg1	absence					1939:1945	the absence	1935:1945	the absence of water	1935:1954	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	9	75	theme	water	1950:1954	arg1	advantageous					1973:1984	advantageous	1973:1984	advantageous	1973:1984	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	0	76	theme	water	48:52	arg1	capacity					154:161	their cellulose swelling capacity	129:161	their cellulose swelling capacity	129:161	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	0	76	theme	water	48:52	arg1	role					18:21	the role	14:21	the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures	14:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	5	77	theme	water	1032:1036	arg1	participation					1015:1027	The participation	1011:1027	The participation of water in the formation of molecular clusters with choline chloride and urea	1011:1106	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	0	78	from	role	18:21	arg1	properties					61:70	the properties	57:70	the properties of choline chloride and urea-based eutectic mixtures	57:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	8	79	theme	%	1763:1763	arg1	content					1747:1753	the water content	1737:1753	the water content of 30 wt%	1737:1763	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	4	80	theme	mixtures	903:910	arg1	capacity					865:872	fiber swelling capacity	850:872	fiber swelling capacity	850:872	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	80	theme	mixtures	903:910	arg1	parameters					834:843	solvatochromic and solvatomagnetic solvent parameters	791:843	solvatochromic and solvatomagnetic solvent parameters	791:843	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	80	theme	mixtures	903:910	arg1	pH					773:774	pH	773:774	pH	773:774	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	80	theme	mixtures	903:910	arg1	viscosity					762:770	viscosity	762:770	viscosity	762:770	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	80	theme	mixtures	903:910	arg1	conductivity					777:788	conductivity	777:788	conductivity	777:788	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	0	81	theme	chloride	83:90	arg1	properties					61:70	the properties	57:70	the properties of choline chloride and urea-based eutectic mixtures	57:123	Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity.					
36413260	5	82	theme	clusters	1068:1075	arg1	formation					1045:1053	the formation	1041:1053	the formation of molecular clusters with choline chloride and urea	1041:1106	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	4	83	theme	different	926:934	arg1	ratios					942:947	different molar ratios	926:947	different molar ratios	926:947	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	2	84	theme	cellulose	368:376	arg1	hydrolysis					378:387	cellulose hydrolysis	368:387	cellulose hydrolysis	368:387	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	6	85	theme	aqueous	1400:1406	arg1	mixtures					1430:1437	aqueous choline chloride-urea mixtures	1400:1437	aqueous choline chloride-urea mixtures	1400:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	5	86	theme	choline	1082:1088	arg1	chloride					1090:1097	choline chloride	1082:1097	choline chloride	1082:1097	The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements.					
36413260	8	87	theme	molecular	1791:1799	arg1	simulations					1801:1811	previous molecular simulations	1782:1811	previous molecular simulations	1782:1811	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	2	88	theme	cellulose-based	424:438	arg1	materials					447:455	cellulose-based (nano) materials	424:455	cellulose-based (nano) materials	424:455	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	6	89	theme	acidity	1389:1395	arg1	determination					1358:1370	the determination	1354:1370	the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures	1354:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	3	90	dep	take	499:502	arg1	unclear					576:582	unclear	576:582	unclear	576:582	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	4	91	theme	water	1004:1008	arg1	absence					987:993	absence	987:993	absence	987:993	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	4	91	theme	water	1004:1008	arg1	presence					974:981	presence	974:981	presence	974:981	Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water.					
36413260	6	92	theme	hydrogen	1375:1382	arg1	acidity					1389:1395	hydrogen bond acidity	1375:1395	hydrogen bond acidity of aqueous choline chloride-urea mixtures	1375:1437	Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride-urea mixtures.					
36413260	1	93	theme	lignocellulose	267:280	arg1	materials					282:290	lignocellulose materials	267:290	lignocellulose materials	267:290	Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials.					
36413260	2	94	theme	materials	447:455	arg1	derivatization					390:403	derivatization	390:403	derivatization	390:403	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	2	94	theme	materials	447:455	arg1	production					410:419	production	410:419	production	410:419	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	2	94	theme	materials	447:455	arg1	hydrolysis					378:387	cellulose hydrolysis	368:387	cellulose hydrolysis	368:387	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	8	95	theme	close	1560:1564	arg1	investigation					1566:1578	The close investigation	1556:1578	The close investigation of the chemical shift of solvatomagnetic probes	1556:1626	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	3	96	theme	additional	588:597	arg1	water					599:603	additional water	588:603	additional water	588:603	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	7	97	theme	magnetic	1505:1512	arg1	methods					1514:1520	solvatochromic and magnetic methods	1486:1520	solvatochromic and magnetic methods	1486:1520	However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends.					
36413260	9	98	theme	cellulose	2052:2060	arg1	fibers					2062:2067	cellulose fibers	2052:2067	cellulose fibers	2052:2067	When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride-urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.					
36413260	8	99	theme	chemical	1647:1654	arg1	environment					1656:1666	the chemical environment	1643:1666	the chemical environment of the choline chloride-urea (1 : 2) mixture	1643:1711	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	7	100	theme	solvatochromic	1486:1499	arg1	methods					1514:1520	solvatochromic and magnetic methods	1486:1520	solvatochromic and magnetic methods	1486:1520	However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends.					
36413260	8	101	theme	chemical	1587:1594	arg1	shift					1596:1600	the chemical shift	1583:1600	the chemical shift of solvatomagnetic probes	1583:1626	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
36413260	3	102	theme	important	621:629	arg1	properties					631:640	many important properties	616:640	many important properties	616:640	Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition.					
36413260	2	103	theme	cellulose	335:343	arg1	swelling					323:330	the swelling	319:330	the swelling of cellulose	319:343	They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials.					
36413260	8	104	theme	choline	1675:1681	arg1	chloride-urea					1683:1695	choline chloride-urea	1675:1695	the choline chloride-urea (1 : 2) mixture	1671:1711	The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride-urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations.					
35488361	1	0	theme	clinical	175:182	arg1	application					200:210	clinical and battlefield application	175:210	clinical and battlefield application	175:210	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	4	1	dep	presence	549:556	arg1	water					558:562	water	558:562	the presence water (nonsolvent)	545:575	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	4	1	dep	presence	549:556	arg1	nonsolvent					565:574	nonsolvent	565:574	nonsolvent	565:574	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	5	2	theme	absorbing	792:800	arg1	capacity					802:809	liquid absorbing capacity	785:809	liquid absorbing capacity	785:809	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	6	3	theme	1:1	996:998	arg1	chitin/gelatin					978:991	chitin/gelatin	978:991	chitin/gelatin of 1:1	978:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	6	4	theme	hemostatic	1095:1104	arg1	performance					1106:1116	the best hemostatic performance	1086:1116	the best hemostatic performance	1086:1116	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	2	5	from	solubility	348:357	arg1	HFIP					395:398	HFIP	395:398	HFIP	395:398	In this study, nearly amorphous chitin is obtained by treating α-chitin with superfine grinding, and the solubility of chitin in hexafluoro-2-propanol (HFIP) is significantly increased.					
35488361	2	5	from	solubility	348:357	arg1	hexafluoro-2-propanol					372:392	hexafluoro-2-propanol	372:392	hexafluoro-2-propanol (HFIP)	372:399	In this study, nearly amorphous chitin is obtained by treating α-chitin with superfine grinding, and the solubility of chitin in hexafluoro-2-propanol (HFIP) is significantly increased.					
35488361	5	6	theme	gelatin	896:902	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	2	7	theme	grinding	330:337	arg1	superfine					320:328	superfine grinding	320:337	superfine grinding	320:337	In this study, nearly amorphous chitin is obtained by treating α-chitin with superfine grinding, and the solubility of chitin in hexafluoro-2-propanol (HFIP) is significantly increased.					
35488361	5	8	with	capacity	802:809	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	1	9	from	demand	165:170	arg1	application					200:210	clinical and battlefield application	175:210	clinical and battlefield application	175:210	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	3	10	theme	chitin	525:530	arg1	solution					532:539	the 8 mg mL-1 chitin solution	511:539	the 8 mg mL-1 chitin solution	511:539	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	4	11	theme	freeze	729:734	arg1	drying					736:741	directional freeze drying	717:741	directional freeze drying of the hydrogel	717:757	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	7	12	theme	in	1123:1124	arg1	study					1131:1135	The in vivo study	1119:1135	The in vivo study	1119:1135	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	4	13	theme	directional	717:727	arg1	drying					736:741	directional freeze drying	717:741	directional freeze drying of the hydrogel	717:757	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	3	14	dep	Chitin	429:434	arg1	mixtures					448:455	mixtures	448:455	mixtures	448:455	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	7	15	dep	in	1123:1124	arg1	vivo					1126:1129	vivo	1126:1129	vivo	1126:1129	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	7	16	theme	injury	1327:1332	arg1	model					1334:1338	rat femoral artery injury model	1308:1338	rat femoral artery injury model	1308:1338	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	5	17	theme	different	876:884	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	1	18	theme	battlefield	188:198	arg1	application					200:210	clinical and battlefield application	175:210	clinical and battlefield application	175:210	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	6	19	theme	chitin/gelatin	978:991	arg1	ratio					969:973	the mass ratio	960:973	the mass ratio of chitin/gelatin of 1:1	960:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	7	20	theme	hemostatic	1155:1164	arg1	time					1166:1169	hemostatic time	1155:1169	hemostatic time of the composite sponge (73 s)	1155:1200	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	1	21	theme	Biomedical	94:103	arg1	materials					105:113	Biomedical materials	94:113	Biomedical materials with effective hemostatic properties	94:150	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	6	22	theme	best	1090:1093	arg1	performance					1106:1116	the best hemostatic performance	1086:1116	the best hemostatic performance	1086:1116	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	4	23	theme	composite	651:659	arg1	sponges					661:667	chitin/gelatin composite sponges	636:667	chitin/gelatin composite sponges with directional pore structure	636:699	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	7	24	theme	composite	1178:1186	arg1	s					1199:1199	73 s	1196:1199	73 s	1196:1199	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	7	24	theme	composite	1178:1186	arg1	sponge					1188:1193	the composite sponge	1174:1193	the composite sponge (73 s)	1174:1200	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	7	25	theme	femoral	1312:1318	arg1	model					1334:1338	rat femoral artery injury model	1308:1338	rat femoral artery injury model	1308:1338	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	4	26	theme	directional	674:684	arg1	structure					691:699	directional pore structure	674:699	directional pore structure	674:699	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	0	27	theme	Hemostatic	0:9	arg1	Performance					11:21	Hemostatic Performance	0:21	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.	0:92	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	5	28	theme	sponges	863:869	arg1	structure					764:772	structure	764:772	structure	764:772	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	5	28	theme	sponges	863:869	arg1	porosity					775:782	porosity	775:782	porosity	775:782	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	5	28	theme	sponges	863:869	arg1	capacity					802:809	liquid absorbing capacity	785:809	liquid absorbing capacity	785:809	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	5	28	theme	sponges	863:869	arg1	properties					845:854	hemostatic properties	834:854	hemostatic properties	834:854	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	5	28	theme	sponges	863:869	arg1	biodegradability					812:827	biodegradability	812:827	biodegradability	812:827	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	7	29	theme	artery	1320:1325	arg1	model					1334:1338	rat femoral artery injury model	1308:1338	rat femoral artery injury model	1308:1338	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	1	30	theme	severe	216:221	arg1	hemorrhage control					223:240	severe hemorrhage control	216:240	severe hemorrhage control	216:240	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	0	31	theme	ɑ-Chitin/Gelatin	26:41	arg1	Sponges					53:59	ɑ-Chitin/Gelatin Composite Sponges	26:59	ɑ-Chitin/Gelatin Composite Sponges	26:59	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	5	32	with	biodegradability	812:827	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	1	33	theme	effective	120:128	arg1	properties					141:150	effective hemostatic properties	120:150	effective hemostatic properties	120:150	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	5	34	theme	hemostatic	834:843	arg1	properties					845:854	hemostatic properties	834:854	hemostatic properties	834:854	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	6	35	theme	mass	964:967	arg1	ratio					969:973	the mass ratio	960:973	the mass ratio of chitin/gelatin of 1:1	960:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	1	36	theme	hemostatic	130:139	arg1	properties					141:150	effective hemostatic properties	120:150	effective hemostatic properties	120:150	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	3	37	theme	gelatin	500:506	arg1	amount					490:495	different amount	480:495	different amount of gelatin	480:506	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	3	37	theme	gelatin	500:506	arg1	gelatin					500:506	gelatin	500:506	gelatin	500:506	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	0	38	theme	Sponges	53:59	arg1	Performance					11:21	Hemostatic Performance	0:21	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.	0:92	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	3	39	theme	mL-1	520:523	arg1	solution					532:539	the 8 mg mL-1 chitin solution	511:539	the 8 mg mL-1 chitin solution	511:539	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	4	40	theme	chitin/gelatin	636:649	arg1	sponges					661:667	chitin/gelatin composite sponges	636:667	chitin/gelatin composite sponges with directional pore structure	636:699	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	2	41	theme	amorphous	265:273	arg1	chitin					275:280	nearly amorphous chitin	258:280	nearly amorphous chitin	258:280	In this study, nearly amorphous chitin is obtained by treating α-chitin with superfine grinding, and the solubility of chitin in hexafluoro-2-propanol (HFIP) is significantly increased.					
35488361	3	42	theme	different	480:488	arg1	amount					490:495	different amount	480:495	different amount of gelatin	480:506	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	3	42	theme	different	480:488	arg1	gelatin					500:506	gelatin	500:506	gelatin	500:506	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	0	43	theme	Composite	43:51	arg1	Sponges					53:59	ɑ-Chitin/Gelatin Composite Sponges	26:59	ɑ-Chitin/Gelatin Composite Sponges	26:59	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	5	44	theme	liquid	785:790	arg1	capacity					802:809	liquid absorbing capacity	785:809	liquid absorbing capacity	785:809	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	4	45	with	sponges	661:667	arg1	structure					691:699	directional pore structure	674:699	directional pore structure	674:699	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	1	46	with	materials	105:113	arg1	properties					141:150	effective hemostatic properties	120:150	effective hemostatic properties	120:150	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	6	47	theme	high	1038:1041	arg1	capacity					1053:1060	high absorbing capacity	1038:1060	high absorbing capacity	1038:1060	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	0	48	theme	Directional	66:76	arg1	Structure					83:91	Directional Pore Structure	66:91	Directional Pore Structure	66:91	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	6	49	with	sponge	948:953	arg1	ratio					969:973	the mass ratio	960:973	the mass ratio of chitin/gelatin of 1:1	960:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	3	50	theme	8 mg	515:518	arg1	solution					532:539	the 8 mg mL-1 chitin solution	511:539	the 8 mg mL-1 chitin solution	511:539	Chitin and gelatin mixtures are prepared by adding different amount of gelatin to the 8 mg mL-1 chitin solution.					
35488361	5	51	with	properties	845:854	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	6	52	with	material	1024:1031	arg1	capacity					1053:1060	high absorbing capacity	1038:1060	high absorbing capacity	1038:1060	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	6	52	with	material	1024:1031	arg1	performance					1106:1116	the best hemostatic performance	1086:1116	the best hemostatic performance	1086:1116	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	6	52	with	material	1024:1031	arg1	hemocompatibility					1063:1079	hemocompatibility	1063:1079	hemocompatibility	1063:1079	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	0	53	with	Performance	11:21	arg1	Structure					83:91	Directional Pore Structure	66:91	Directional Pore Structure	66:91	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	2	54	theme	chitin	362:367	arg1	solubility					348:357	the solubility	344:357	the solubility of chitin in hexafluoro-2-propanol (HFIP)	344:399	In this study, nearly amorphous chitin is obtained by treating α-chitin with superfine grinding, and the solubility of chitin in hexafluoro-2-propanol (HFIP) is significantly increased.					
35488361	5	55	dep	structure	764:772	arg1	The					760:762	The	760:762	The	760:762	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	7	56	theme	gelatin	1282:1288	arg1	sponge					1290:1295	gelatin sponge	1282:1295	gelatin sponge (116 s)	1282:1303	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	7	56	theme	gelatin	1282:1288	arg1	s					1302:1302	116 s	1298:1302	116 s	1298:1302	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	6	57	theme	absorbing	1043:1051	arg1	capacity					1053:1060	high absorbing capacity	1038:1060	high absorbing capacity	1038:1060	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	7	58	theme	rat	1308:1310	arg1	model					1334:1338	rat femoral artery injury model	1308:1338	rat femoral artery injury model	1308:1338	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	5	59	with	porosity	775:782	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	4	60	theme	hydrogel	750:757	arg1	drying					736:741	directional freeze drying	717:741	directional freeze drying of the hydrogel	717:757	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	1	61	theme	great	159:163	arg1	demand					165:170	great demand	159:170	great demand in clinical and battlefield application for severe hemorrhage control	159:240	Biomedical materials with effective hemostatic properties are in great demand in clinical and battlefield application for severe hemorrhage control.					
35488361	7	62	theme	chitin	1249:1254	arg1	sponge					1256:1261	chitin sponge	1249:1261	chitin sponge (132 s)	1249:1269	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	7	62	theme	chitin	1249:1254	arg1	s					1268:1268	132 s	1264:1268	132 s	1264:1268	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	6	63	theme	hemostatic	1013:1022	arg1	sponge					948:953	the sponge	944:953	the sponge with the mass ratio of chitin/gelatin of 1:1	944:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	6	63	theme	hemostatic	1013:1022	arg1	material					1024:1031	potential hemostatic material	1003:1031	potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance	1003:1116	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	0	64	theme	Pore	78:81	arg1	Structure					83:91	Directional Pore Structure	66:91	Directional Pore Structure	66:91	Hemostatic Performance of ɑ-Chitin/Gelatin Composite Sponges with Directional Pore Structure.					
35488361	5	65	with	structure	764:772	arg1	ratios					886:891	different ratios	876:891	different ratios of gelatin	876:902	The structure, porosity, liquid absorbing capacity, biodegradability, and hemostatic properties of the sponges with different ratios of gelatin are investigated.					
35488361	4	66	theme	pore	686:689	arg1	structure					691:699	directional pore structure	674:699	directional pore structure	674:699	In the presence water (nonsolvent), the mixtures are gelled as HFIP is replaced by water, and chitin/gelatin composite sponges with directional pore structure are prepared by directional freeze drying of the hydrogel.					
35488361	7	67	theme	sponge	1188:1193	arg1	time					1166:1169	hemostatic time	1155:1169	hemostatic time of the composite sponge (73 s)	1155:1200	The in vivo study demonstrates that hemostatic time of the composite sponge (73 s) is much shorter than of that of gauze (193 s), chitin sponge (132 s) as well as gelatin sponge (116 s) in rat femoral artery injury model.					
35488361	6	68	theme	potential	1003:1011	arg1	sponge					948:953	the sponge	944:953	the sponge with the mass ratio of chitin/gelatin of 1:1	944:998	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
35488361	6	68	theme	potential	1003:1011	arg1	material					1024:1031	potential hemostatic material	1003:1031	potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance	1003:1116	The results show that the sponge with the mass ratio of chitin/gelatin of 1:1 is potential hemostatic material with high absorbing capacity, hemocompatibility, and the best hemostatic performance.					
37205788	4	0	theme	DD	544:545	arg1	properties					658:667	antioxidant properties	646:667	antioxidant properties	646:667	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	0	theme	DD	544:545	arg1	structure					575:583	the structure	571:583	the structure	571:583	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	0	theme	DD	544:545	arg1	composition					590:600	the composition	586:600	the composition	586:600	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	0	theme	DD	544:545	arg1	effects					524:530	the effects	520:530	the effects of chitosan DD on the reaction extent	520:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	0	theme	DD	544:545	arg1	properties					634:643	the physicochemical properties	614:643	the physicochemical properties	614:643	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	0	theme	DD	544:545	arg1	properties					695:704	bacterial inhibitory properties	674:704	bacterial inhibitory properties	674:704	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	6	1	theme	reaction	1199:1206	arg1	degree					1189:1194	the degree	1185:1194	the degree of reaction	1185:1206	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	8	2	theme	mannose	1580:1586	arg1	incorporation					1563:1575	the incorporation	1559:1575	the incorporation of mannose	1559:1586	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	8	3	theme	antioxidant	1521:1531	arg1	activity					1533:1540	antioxidant activity	1521:1540	Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity	1400:1540	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	4	4	theme	inhibitory	684:693	arg1	properties					695:704	bacterial inhibitory properties	674:704	bacterial inhibitory properties	674:704	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	4	theme	inhibitory	684:693	arg1	effects					524:530	the effects	520:530	the effects of chitosan DD on the reaction extent	520:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	2	5	theme	water-soluble	287:299	arg1	derivatives					310:320	the water-soluble chitosan derivatives	283:320	the water-soluble chitosan derivatives	283:320	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	11	6	theme	such	1999:2002	arg1	derivatives					2004:2014	such derivatives	1999:2014	such derivatives	1999:2014	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	7	7	theme	Mc-mrps	1301:1307	arg1	potential					1266:1274	zeta potential	1261:1274	zeta potential	1261:1274	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	7	7	theme	Mc-mrps	1301:1307	arg1	size					1289:1292	particle size	1280:1292	particle size	1280:1292	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	5	8	theme	experimental	815:826	arg1	data					828:831	the experimental data	811:831	the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs	811:1075	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	11	9	contain	had	1854:1856	arg1	DD					1839:1840	The DD	1835:1840	The DD of chitosan	1835:1852	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	11	9	contain	had	1854:1856	arg2	effect					1872:1877	a significant effect	1858:1877	a significant effect	1858:1877	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	6	10	theme	significant	1161:1171	arg1	increase					1173:1180	a significant increase	1159:1180	a significant increase in the degree of reaction	1159:1206	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	1	11	theme	antibacterial	204:216	arg1	properties					218:227	the physical, chemical, and antibacterial properties	176:227	the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives	176:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	7	12	theme	zeta	1261:1264	arg1	potential					1266:1274	zeta potential	1261:1274	zeta potential	1261:1274	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	7	13	theme	particle	1280:1287	arg1	size					1289:1292	particle size	1280:1292	particle size	1280:1292	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	2	14	theme	Maillard	338:345	arg1	reaction					347:354	the Maillard reaction	334:354	the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose	334:447	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	2	14	theme	Maillard	338:345	arg1	MR					357:358	MR	357:358	MR	357:358	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	8	15	dep	bacteria	1465:1472	arg1	typhimurium					1497:1507	Salmonella typhimurium	1486:1507	Salmonella typhimurium	1486:1507	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	8	15	dep	bacteria	1465:1472	arg1	E.coli					1475:1480	E.coli	1475:1480	E.coli	1475:1480	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	1	16	theme	chitosan	246:253	arg1	derivatives					255:265	water-soluble chitosan derivatives	232:265	water-soluble chitosan derivatives	232:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	6	17	theme	color	1209:1213	arg1	△E					1227:1228	△E	1227:1228	△E	1227:1228	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	6	17	theme	color	1209:1213	arg1	difference					1215:1224	color difference	1209:1224	color difference (△E)	1209:1229	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	2	18	theme	chitosan	301:308	arg1	derivatives					310:320	the water-soluble chitosan derivatives	283:320	the water-soluble chitosan derivatives	283:320	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	4	19	theme	physicochemical	618:632	arg1	properties					634:643	the physicochemical properties	614:643	the physicochemical properties	614:643	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	19	theme	physicochemical	618:632	arg1	effects					524:530	the effects	520:530	the effects of chitosan DD on the reaction extent	520:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	9	20	theme	DD	1635:1636	arg1	increase					1619:1626	the increase	1615:1626	the increase of the DD of chitosan	1615:1648	This was also achieved by the increase of the DD of chitosan.					
37205788	11	21	theme	reference	1933:1941	arg1	Mc-mrp					1904:1909	the Mc-mrp	1900:1909	the Mc-mrp	1900:1909	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	11	21	theme	reference	1933:1941	arg1	point					1943:1947	a reference point	1931:1947	a reference point for the subsequent preparation and application of such derivatives	1931:2014	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	5	22	theme	different	1063:1071	arg1	DDs					1073:1075	different DDs	1063:1075	different DDs	1063:1075	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	9	23	theme	chitosan	1641:1648	arg1	DD					1635:1636	the DD	1631:1636	the DD of chitosan	1631:1648	This was also achieved by the increase of the DD of chitosan.					
37205788	0	24	from	Effect	0:5	arg1	antioxidant					67:77	antioxidant	67:77	antioxidant	67:77	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	0	24	from	Effect	0:5	arg1	activities					97:106	antibacterial activities	83:106	antibacterial activities	83:106	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	0	24	from	Effect	0:5	arg1	properties					55:64	physicochemical properties	39:64	physicochemical properties	39:64	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	4	25	theme	finished	713:720	arg1	Mc-mrps					767:773	Mc-mrps	767:773	Mc-mrps	767:773	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	25	theme	finished	713:720	arg1	products					757:764	the finished chitosan-mannose Maillard reaction products	709:764	the finished chitosan-mannose Maillard reaction products (Mc-mrps)	709:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	8	26	theme	Gram-positive	1400:1412	arg1	bacteria					1465:1472	Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria	1400:1472	Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity	1400:1540	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	4	27	theme	Maillard	739:746	arg1	Mc-mrps					767:773	Mc-mrps	767:773	Mc-mrps	767:773	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	27	theme	Maillard	739:746	arg1	products					757:764	the finished chitosan-mannose Maillard reaction products	709:764	the finished chitosan-mannose Maillard reaction products (Mc-mrps)	709:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	0	28	theme	chitosan-mannose	111:126	arg1	derivatives					128:138	chitosan-mannose derivatives	111:138	chitosan-mannose derivatives	111:138	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	5	29	dep	Fourier	851:857	arg1	transform					859:867	transform	859:867	transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR	859:1022	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	4	30	from	effects	524:530	arg1	extent					563:568	the reaction extent	550:568	the reaction extent	550:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	10	31	dep	antioxidant	1793:1803	arg1	activities					1823:1832	activities	1823:1832	activities	1823:1832	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	0	32	theme	deacetylation	10:22	arg1	Effect					0:5	Effect	0:5	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.	0:139	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	6	33	from	solubility	1236:1245	arg1	degree					1189:1194	the degree	1185:1194	the degree of reaction	1185:1206	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	4	34	theme	effects	524:530	arg1	evaluations					505:515	Systematic evaluations	494:515	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps)	494:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	0	35	theme	chitosan	27:34	arg1	deacetylation					10:22	deacetylation	10:22	deacetylation of chitosan	10:34	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	6	36	from	difference	1215:1224	arg1	degree					1189:1194	the degree	1185:1194	the degree of reaction	1185:1206	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	8	37	theme	Gram-negative	1451:1463	arg1	bacteria					1465:1472	Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria	1400:1472	Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity	1400:1540	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	3	38	theme	organic	453:459	arg1	reagent					461:467	No organic reagent	450:467	No organic reagent	450:467	No organic reagent was used in the process.					
37205788	0	39	theme	physicochemical	39:53	arg1	properties					55:64	physicochemical properties	39:64	physicochemical properties	39:64	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	5	40	theme	chromatography-mass	972:990	arg1	PY-GC-MS					1002:1009	PY-GC-MS	1002:1009	PY-GC-MS	1002:1009	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	40	theme	chromatography-mass	972:990	arg1	analysis					992:999	Pyrolysis-gas chromatography-mass analysis	958:999	Pyrolysis-gas chromatography-mass analysis (PY-GC-MS)	958:1010	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	4	41	theme	Systematic	494:503	arg1	evaluations					505:515	Systematic evaluations	494:515	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps)	494:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	10	42	theme	novel	1745:1749	arg1	polysaccharide					1766:1779	a novel, water-soluble polysaccharide	1743:1779	a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities	1743:1832	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	4	43	theme	products	757:764	arg1	evaluations					505:515	Systematic evaluations	494:515	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps)	494:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	1	44	theme	derivatives	255:265	arg1	properties					218:227	the physical, chemical, and antibacterial properties	176:227	the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives	176:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	4	45	theme	reaction	554:561	arg1	extent					563:568	the reaction extent	550:568	the reaction extent	550:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	2	46	theme	deacetylation	393:405	arg1	degree					383:388	the degree	379:388	the degree of deacetylation (DD) being 50%, 70%, and 90%	379:434	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	10	47	dep	novel	1745:1749	arg1	water-soluble					1752:1764	water-soluble	1752:1764	water-soluble	1752:1764	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	4	48	from	extent	563:568	arg1	evaluations					505:515	Systematic evaluations	494:515	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps)	494:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	6	49	from	increase	1173:1180	arg1	degree					1189:1194	the degree	1185:1194	the degree of reaction	1185:1206	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	7	50	theme	chitosan	1343:1350	arg1	DD					1337:1338	the DD	1333:1338	the DD of chitosan	1333:1350	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	4	51	theme	chitosan	535:542	arg1	DD					544:545	chitosan DD	535:545	chitosan DD	535:545	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	11	52	theme	subsequent	1957:1966	arg1	preparation					1968:1978	preparation	1968:1978	preparation	1968:1978	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	1	53	theme	chemical	190:197	arg1	properties					218:227	the physical, chemical, and antibacterial properties	176:227	the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives	176:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	11	54	theme	derivatives	2004:2014	arg1	preparation					1968:1978	preparation	1968:1978	preparation	1968:1978	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	11	54	theme	derivatives	2004:2014	arg1	application					1984:1994	application	1984:1994	application	1984:1994	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	11	55	theme	Mc-mrp	1904:1909	arg1	properties					1886:1895	the properties	1882:1895	the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives	1882:2014	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	7	56	dep	potential	1266:1274	arg1	The					1257:1259	The	1257:1259	The	1257:1259	The zeta potential and particle size of the Mc-mrps were also influenced by the DD of chitosan.					
37205788	11	57	dep	preparation	1968:1978	arg1	the					1953:1955	the	1953:1955	the	1953:1955	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	10	58	theme	study	1681:1685	arg1	results					1666:1672	The results	1662:1672	The results of the study	1662:1685	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	1	59	theme	water-soluble	232:244	arg1	derivatives					255:265	water-soluble chitosan derivatives	232:265	water-soluble chitosan derivatives	232:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	5	60	theme	infrared	869:876	arg1	spectroscopy					878:889	infrared spectroscopy	869:889	infrared spectroscopy (FTIR)	869:896	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	60	theme	infrared	869:876	arg1	FTIR					892:895	FTIR	892:895	FTIR	892:895	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	6	61	theme	chitosan	1143:1150	arg1	DD					1137:1138	the DD	1133:1138	the DD of chitosan	1133:1150	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	4	62	theme	antioxidant	646:656	arg1	properties					658:667	antioxidant properties	646:667	antioxidant properties	646:667	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	62	theme	antioxidant	646:656	arg1	effects					524:530	the effects	520:530	the effects of chitosan DD on the reaction extent	520:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	3	63	used	used	473:476	arg2	reagent					461:467	No organic reagent	450:467	No organic reagent	450:467	No organic reagent was used in the process.					
37205788	2	64	theme	derivatives	310:320	arg1	Preparation					268:278	Preparation	268:278	Preparation of the water-soluble chitosan derivatives	268:320	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	5	65	contain	had	1077:1079	arg2	components					1106:1115	components	1106:1115	components	1106:1115	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	65	contain	had	1077:1079	arg1	RESULTS					794:800	RESULTS	794:800	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs	794:1075	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	65	contain	had	1077:1079	arg2	structures					1091:1100	different structures	1081:1100	different structures	1081:1100	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	10	66	dep	CONCLUSION	1651:1660	arg1	suggest					1687:1693	suggest	1687:1693	suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities	1687:1832	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	11	67	theme	chitosan	1845:1852	arg1	DD					1839:1840	The DD	1835:1840	The DD of chitosan	1835:1852	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	8	68	theme	antimicrobial	1371:1383	arg1	action					1385:1390	the antimicrobial action	1367:1390	the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity	1367:1540	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	0	69	theme	antibacterial	83:95	arg1	activities					97:106	antibacterial activities	83:106	antibacterial activities	83:106	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	1	70	theme	physical	180:187	arg1	properties					218:227	the physical, chemical, and antibacterial properties	176:227	the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives	176:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	0	71	theme	derivatives	128:138	arg1	antioxidant					67:77	antioxidant	67:77	antioxidant	67:77	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	0	71	theme	derivatives	128:138	arg1	activities					97:106	antibacterial activities	83:106	antibacterial activities	83:106	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	0	71	theme	derivatives	128:138	arg1	properties					55:64	physicochemical properties	39:64	physicochemical properties	39:64	Effect of deacetylation of chitosan on physicochemical properties, antioxidant and antibacterial activities of chitosan-mannose derivatives.					
37205788	10	72	with	polysaccharide	1766:1779	arg1	antimicrobial					1809:1821	antimicrobial	1809:1821	antimicrobial	1809:1821	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	10	72	with	polysaccharide	1766:1779	arg1	antioxidant					1793:1803	antioxidant	1793:1803	antioxidant	1793:1803	CONCLUSION The results of the study suggest that chitosan was derived with mannose to yield a novel, water-soluble polysaccharide with better antioxidant and antimicrobial activities.					
37205788	1	73	dep	BACKGROUND	141:150	arg1	investigates					163:174	investigates	163:174	investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives	163:265	BACKGROUND This paper investigates the physical, chemical, and antibacterial properties of water-soluble chitosan derivatives.					
37205788	6	74	from	increase	1121:1128	arg1	DD					1137:1138	the DD	1133:1138	the DD of chitosan	1133:1150	An increase in the DD of chitosan led to a significant increase in the degree of reaction, color difference (△E), and solubility (p<0.05).					
37205788	4	75	theme	bacterial	674:682	arg1	properties					695:704	bacterial inhibitory properties	674:704	bacterial inhibitory properties	674:704	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	75	theme	bacterial	674:682	arg1	effects					524:530	the effects	520:530	the effects of chitosan DD on the reaction extent	520:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	5	76	theme	thermogravimetric	899:915	arg1	TGA					927:929	TGA	927:929	TGA	927:929	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	76	theme	thermogravimetric	899:915	arg1	analysis					917:924	thermogravimetric analysis	899:924	thermogravimetric analysis (TGA)	899:930	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	2	77	dep	chitosan	369:376	arg1	degree					383:388	the degree	379:388	the degree of deacetylation (DD) being 50%, 70%, and 90%	379:434	Preparation of the water-soluble chitosan derivatives was done by the Maillard reaction (MR) between chitosan (the degree of deacetylation (DD) being 50%, 70%, and 90%) and mannose.					
37205788	4	78	from	evaluations	505:515	arg1	extent					563:568	the reaction extent	550:568	the reaction extent	550:568	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	5	79	theme	different	1081:1089	arg1	structures					1091:1100	different structures	1081:1100	different structures	1081:1100	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	80	theme	Pyrolysis-gas	958:970	arg1	PY-GC-MS					1002:1009	PY-GC-MS	1002:1009	PY-GC-MS	1002:1009	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	80	theme	Pyrolysis-gas	958:970	arg1	analysis					992:999	Pyrolysis-gas chromatography-mass analysis	958:999	Pyrolysis-gas chromatography-mass analysis (PY-GC-MS)	958:1010	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	81	theme	X-ray	933:937	arg1	XRD					952:954	XRD	952:954	XRD	952:954	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	5	81	theme	X-ray	933:937	arg1	diffraction					939:949	X-ray diffraction	933:949	X-ray diffraction (XRD)	933:955	RESULTS Based on the experimental data obtained from the Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), Pyrolysis-gas chromatography-mass analysis (PY-GC-MS), and 1H-NMR, the Mc-mrps formed from chitosan with different DDs had different structures and components.					
37205788	4	82	theme	chitosan-mannose	722:737	arg1	Mc-mrps					767:773	Mc-mrps	767:773	Mc-mrps	767:773	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	82	theme	chitosan-mannose	722:737	arg1	products					757:764	the finished chitosan-mannose Maillard reaction products	709:764	the finished chitosan-mannose Maillard reaction products (Mc-mrps)	709:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	83	theme	reaction	748:755	arg1	Mc-mrps					767:773	Mc-mrps	767:773	Mc-mrps	767:773	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	4	83	theme	reaction	748:755	arg1	products					757:764	the finished chitosan-mannose Maillard reaction products	709:764	the finished chitosan-mannose Maillard reaction products (Mc-mrps)	709:774	Systematic evaluations of the effects of chitosan DD on the reaction extent, the structure, the composition, as well as the physicochemical properties, antioxidant properties, and bacterial inhibitory properties of the finished chitosan-mannose Maillard reaction products (Mc-mrps) were carried out.					
37205788	11	84	theme	significant	1860:1870	arg1	effect					1872:1877	a significant effect	1858:1877	a significant effect	1858:1877	The DD of chitosan had a significant effect on the properties of the Mc-mrp, which can serve as a reference point for the subsequent preparation and application of such derivatives.					
37205788	8	85	dep	Gram-positive	1400:1412	arg1	S.aureus					1415:1422	S.aureus	1415:1422	S.aureus	1415:1422	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
37205788	8	85	dep	Gram-positive	1400:1412	arg1	subtilis					1437:1444	Bacillus subtilis	1428:1444	Bacillus subtilis	1428:1444	Additionally, the antimicrobial action against Gram-positive (S.aureus and Bacillus subtilis) and Gram-negative bacteria (E.coli and Salmonella typhimurium) as well as antioxidant activity were enhanced by the incorporation of mannose.					
35878669	4	0	theme	wearable	924:931	arg1	sensor					933:938	a wearable sensor	922:938	a wearable sensor	922:938	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	0	theme	wearable	924:931	arg1	hydrogel					899:906	the hydrogel	895:906	the hydrogel	895:906	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	1	theme	in-situ	823:829	arg1	reaction					845:852	in-situ silver mirror reaction	823:852	in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles)	823:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	0	2	with	starch	29:34	arg1	toughness					71:79	high toughness	66:79	high toughness	66:79	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	0	2	with	starch	29:34	arg1	capability					98:107	self-healing capability	85:107	self-healing capability	85:107	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	1	3	theme	high	155:158	arg1	toughness					160:168	high toughness	155:168	high toughness	155:168	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	5	4	dep	glove	1085:1089	arg1	E-glove					1092:1098	E-glove	1092:1098	E-glove	1092:1098	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	0	5	theme	high	66:69	arg1	toughness					71:79	high toughness	66:79	high toughness	66:79	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	3	6	theme	failure	660:666	arg1	strain					668:673	a failure strain	658:673	a failure strain of 1500 %	658:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	6	7	theme	new	1257:1259	arg1	route					1261:1265	a new route	1255:1265	a new route for the fabrication of multifunctional hydrogels with high performance	1255:1336	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	2	8	theme	"	330:330	arg1	preparation					307:317	preparation	307:317	preparation of "Liangpi" (cold noodles, a traditional Chinese food)	307:373	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	0	9	theme	self-healing	85:96	arg1	capability					98:107	self-healing capability	85:107	self-healing capability	85:107	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	5	10	theme	printability	1060:1071	arg1	advantage					1043:1051	the advantage	1039:1051	the advantage of its printability	1039:1071	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	4	11	theme	2.027	991:995	arg1	factor					981:986	high gauge factor	970:986	high gauge factor of 2.027 and good durability (1000 cycles)	970:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	12	theme	high	686:689	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	12	theme	high	686:689	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	13	theme	physical	509:516	arg1	network					536:542	the physical dual cross-linked network	505:542	the physical dual cross-linked network	505:542	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	2	14	dep	"	330:330	arg1	food					369:372	a traditional Chinese food	347:372	a traditional Chinese food	347:372	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	2	14	dep	"	330:330	arg1	noodles					338:344	cold noodles	333:344	cold noodles	333:344	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	6	15	theme	human	1409:1413	arg1	motions					1415:1421	human motions	1409:1421	human motions	1409:1421	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	1	16	theme	huge	265:268	arg1	challenge					270:278	a huge challenge	263:278	a huge challenge	263:278	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	2	17	theme	heating	471:477	arg1	process					479:485	a simple heating process	462:485	a simple heating process	462:485	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	1	18	with	hydrogels	126:134	arg1	property					203:210	robust mechanical property	185:210	robust mechanical property	185:210	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	1	18	with	hydrogels	126:134	arg1	toughness					160:168	high toughness	155:168	high toughness	155:168	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	1	18	with	hydrogels	126:134	arg1	self-healing					171:182	self-healing	171:182	self-healing	171:182	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	1	18	with	hydrogels	126:134	arg1	printability					141:152	printability	141:152	printability	141:152	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	1	18	with	hydrogels	126:134	arg1	conductivity					216:227	conductivity	216:227	conductivity	216:227	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	0	19	with	latex	55:59	arg1	toughness					71:79	high toughness	66:79	high toughness	66:79	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	0	19	with	latex	55:59	arg1	capability					98:107	self-healing capability	85:107	self-healing capability	85:107	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	4	20	theme	1000 cycles	1018:1028	arg1	factor					981:986	high gauge factor	970:986	high gauge factor of 2.027 and good durability (1000 cycles)	970:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	2	21	theme	Chinese	361:367	arg1	food					369:372	a traditional Chinese food	347:372	a traditional Chinese food	347:372	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	2	21	theme	Chinese	361:367	arg1	noodles					338:344	cold noodles	333:344	cold noodles	333:344	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	2	22	theme	simple	464:469	arg1	process					479:485	a simple heating process	462:485	a simple heating process	462:485	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	3	23	theme	%	683:683	arg1	strain					668:673	a failure strain	658:673	a failure strain of 1500 %	658:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	2	24	theme	traditional	349:359	arg1	food					369:372	a traditional Chinese food	347:372	a traditional Chinese food	347:372	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	2	24	theme	traditional	349:359	arg1	noodles					338:344	cold noodles	333:344	cold noodles	333:344	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	6	25	theme	new	1350:1352	arg1	road					1354:1357	a new road	1348:1357	a new road for designing complex wearable sensors to monitor human motions	1348:1421	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	2	26	theme	rubber	441:446	arg1	latex					448:452	natural rubber latex	433:452	natural rubber latex	433:452	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	6	27	with	hydrogels	1306:1314	arg1	performance					1326:1336	high performance	1321:1336	high performance	1321:1336	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	4	28	theme	human	951:955	arg1	motions					957:963	human motions	951:963	human motions with high gauge factor of 2.027 and good durability (1000 cycles)	951:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	29	theme	silver	831:836	arg1	reaction					845:852	in-situ silver mirror reaction	823:852	in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles)	823:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	1	30	theme	robust	185:190	arg1	property					203:210	robust mechanical property	185:210	robust mechanical property	185:210	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	4	31	theme	gauge	975:979	arg1	factor					981:986	high gauge factor	970:986	high gauge factor of 2.027 and good durability (1000 cycles)	970:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	32	with	motions	957:963	arg1	factor					981:986	high gauge factor	970:986	high gauge factor of 2.027 and good durability (1000 cycles)	970:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	33	theme	conductive	777:786	arg1	hydrogel					788:795	a conductive hydrogel	775:795	a conductive hydrogel	775:795	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	34	theme	dual	518:521	arg1	network					536:542	the physical dual cross-linked network	505:542	the physical dual cross-linked network	505:542	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	5	35	theme	hand	1214:1217	arg1	motions					1219:1225	the hand motions	1210:1225	the hand motions	1210:1225	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	1	36	theme	mechanical	192:201	arg1	property					203:210	robust mechanical property	185:210	robust mechanical property	185:210	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	2	37	theme	satisfactory	378:389	arg1	hydrogel					391:398	a satisfactory hydrogel	376:398	a satisfactory hydrogel	376:398	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	5	38	from	printing	1129:1136	arg1	glove					1172:1176	glove	1172:1176	glove	1172:1176	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	3	39	theme	tensile	626:632	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	39	theme	tensile	626:632	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	40	theme	cross-linked	523:534	arg1	network					536:542	the physical dual cross-linked network	505:542	the physical dual cross-linked network	505:542	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	4	41	dep	reaction	845:852	arg1	mirror					838:843	mirror	838:843	mirror	838:843	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	2	42	theme	natural	433:439	arg1	latex					448:452	natural rubber latex	433:452	natural rubber latex	433:452	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	3	43	theme	6.28 MJ m-3	704:714	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	43	theme	6.28 MJ m-3	704:714	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	44	theme	composite	559:567	arg1	hydrogels					569:577	the resultant composite hydrogels	545:577	the resultant composite hydrogels	545:577	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	45	with	stress	634:639	arg1	strain					668:673	a failure strain	658:673	a failure strain of 1500 %	658:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	6	46	theme	high	1321:1324	arg1	performance					1326:1336	high performance	1321:1336	high performance	1321:1336	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	4	47	used	used	914:917	arg2	sensor					933:938	a wearable sensor	922:938	a wearable sensor	922:938	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	47	used	used	914:917	arg2	hydrogel					899:906	the hydrogel	895:906	the hydrogel	895:906	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	48	dep	properties	605:614	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	48	dep	properties	605:614	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	0	49	theme	rubber	48:53	arg1	latex					55:59	natural rubber latex	40:59	natural rubber latex	40:59	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	3	50	theme	ultimate	617:624	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	50	theme	ultimate	617:624	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	2	51	theme	Liangpi	323:329	arg1	"					330:330	"Liangpi"	322:330	"Liangpi" (cold noodles, a traditional Chinese food)	322:373	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	0	52	theme	natural	40:46	arg1	latex					55:59	natural rubber latex	40:59	natural rubber latex	40:59	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	3	53	theme	good	718:721	arg1	ability					736:742	good self-healing ability	718:742	good self-healing ability	718:742	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	53	theme	good	718:721	arg1	properties					605:614	high mechanical properties	589:614	high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3)	589:715	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	54	theme	resultant	549:557	arg1	hydrogels					569:577	the resultant composite hydrogels	545:577	the resultant composite hydrogels	545:577	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	1	55	theme	bio-based	116:124	arg1	hydrogels					126:134	Fully bio-based hydrogels	110:134	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity	110:227	Fully bio-based hydrogels with printability, high toughness, self-healing, robust mechanical property and conductivity are highly desired but now remain a huge challenge.					
35878669	4	56	theme	durability	1006:1015	arg1	1000 cycles					1018:1028	good durability (1000 cycles)	1001:1029	good durability (1000 cycles)	1001:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	57	theme	self-healing	723:734	arg1	ability					736:742	good self-healing ability	718:742	good self-healing ability	718:742	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	57	theme	self-healing	723:734	arg1	properties					605:614	high mechanical properties	589:614	high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3)	589:715	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	4	58	theme	heating	865:871	arg1	process					873:879	the heating process	861:879	the heating process	861:879	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	4	59	theme	high	970:973	arg1	factor					981:986	high gauge factor	970:986	high gauge factor of 2.027 and good durability (1000 cycles)	970:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	60	theme	mechanical	594:603	arg1	ability					736:742	good self-healing ability	718:742	good self-healing ability	718:742	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	60	theme	mechanical	594:603	arg1	printability					751:762	3D printability	748:762	3D printability	748:762	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	60	theme	mechanical	594:603	arg1	properties					605:614	high mechanical properties	589:614	high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3)	589:715	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	4	61	theme	good	1001:1004	arg1	1000 cycles					1018:1028	good durability (1000 cycles)	1001:1029	good durability (1000 cycles)	1001:1029	Moreover, a conductive hydrogel can be easily obtained by in-situ silver mirror reaction during the heating process, which enable the hydrogel to be used as a wearable sensor to monitor human motions with high gauge factor of 2.027 and good durability (1000 cycles).					
35878669	3	62	from	network	536:542	arg1	Benefitting					488:498	Benefitting	488:498	Benefitting	488:498	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	5	63	theme	precursor	1142:1150	arg1	sol					1152:1154	the precursor sol	1138:1154	the precursor sol	1138:1154	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	6	64	theme	multifunctional	1290:1304	arg1	hydrogels					1306:1314	multifunctional hydrogels	1290:1314	multifunctional hydrogels with high performance	1290:1336	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	3	65	theme	1.01 MPa	644:651	arg1	stress					634:639	ultimate tensile stress	617:639	ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %	617:683	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	65	theme	1.01 MPa	644:651	arg1	toughness					691:699	high toughness	686:699	high toughness of 6.28 MJ m-3	686:714	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	0	66	dep	hydrogels	10:18	arg1	based					20:24	based	20:24	hydrogels based on starch and natural rubber latex with high toughness and self-healing capability	10:107	Printable hydrogels based on starch and natural rubber latex with high toughness and self-healing capability.					
35878669	6	67	theme	hydrogels	1306:1314	arg1	fabrication					1275:1285	the fabrication	1271:1285	the fabrication of multifunctional hydrogels with high performance	1271:1336	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	6	68	theme	wearable	1381:1388	arg1	sensors					1390:1396	complex wearable sensors	1373:1396	complex wearable sensors	1373:1396	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35878669	3	69	theme	3D	748:749	arg1	printability					751:762	3D printability	748:762	3D printability	748:762	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	69	theme	3D	748:749	arg1	properties					605:614	high mechanical properties	589:614	high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3)	589:715	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	70	link	cross-linked	523:534	arg1	network					536:542	the physical dual cross-linked network	505:542	the physical dual cross-linked network	505:542	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	71	theme	high	589:592	arg1	ability					736:742	good self-healing ability	718:742	good self-healing ability	718:742	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	71	theme	high	589:592	arg1	printability					751:762	3D printability	748:762	3D printability	748:762	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	3	71	theme	high	589:592	arg1	properties					605:614	high mechanical properties	589:614	high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3)	589:715	Benefitting from the physical dual cross-linked network, the resultant composite hydrogels exhibited high mechanical properties (ultimate tensile stress of 1.01 MPa with a failure strain of 1500 %, high toughness of 6.28 MJ m-3), good self-healing ability and 3D printability.					
35878669	5	72	used	used	1195:1198	arg2	glove					1085:1089	glove	1085:1089	glove	1085:1089	Taking the advantage of its printability, electronic glove (E-glove) has been easily prepared by printing the precursor sol directly on the glove and successfully used to detect the hand motions exactly.					
35878669	2	73	theme	cold	333:336	arg1	food					369:372	a traditional Chinese food	347:372	a traditional Chinese food	347:372	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	2	73	theme	cold	333:336	arg1	noodles					338:344	cold noodles	333:344	cold noodles	333:344	In this work, inspired by preparation of "Liangpi" (cold noodles, a traditional Chinese food), a satisfactory hydrogel was constructed using starch and natural rubber latex through a simple heating process.					
35878669	6	74	theme	complex	1373:1379	arg1	sensors					1390:1396	complex wearable sensors	1373:1396	complex wearable sensors	1373:1396	This work provides a new route for the fabrication of multifunctional hydrogels with high performance and opens a new road for designing complex wearable sensors to monitor human motions.					
35283851	6	0	theme	chemical	997:1004	arg1	methods					1006:1012	chemical methods	997:1012	chemical methods	997:1012	The glycopolymers have been detected by chemical methods and spectroscopic analyses.					
35283851	0	1	theme	Structural	82:91	arg1	Changes					93:99	Structural Changes	82:99	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.	0:133	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	8	2	theme	psychrerythraea	1228:1242	arg1	34H					1244:1246	C. psychrerythraea 34H	1225:1246	C. psychrerythraea 34H	1225:1246	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	5	3	theme	planktonic	916:925	arg1	conditions					927:936	planktonic conditions	916:936	planktonic conditions	916:936	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	0	4	theme	Different	104:112	arg1	Temperatures					121:132	Different Growth Temperatures	104:132	Different Growth Temperatures	104:132	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	5	5	from	response	792:799	arg1	terms					829:833	terms	829:833	terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	829:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	7	6	theme	psychrerythraea	1105:1119	arg1	34H					1121:1123	C. psychrerythraea 34H	1102:1123	C. psychrerythraea 34H	1102:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	7	7	theme	34H	1121:1123	arg1	matrix					1092:1097	the biofilm matrix	1080:1097	the biofilm matrix of C. psychrerythraea 34H	1080:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	8	8	from	glyconjugates	1300:1312	arg1	response					1317:1324	response	1317:1324	response to temperature fluctuations	1317:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	3	9	theme	C.	543:544	arg1	34H					562:564	C. psychrerythraea 34H	543:564	C. psychrerythraea 34H	543:564	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	8	10	theme	glyconjugates	1300:1312	arg1	production					1265:1274	the production	1261:1274	the production	1261:1274	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	8	10	theme	glyconjugates	1300:1312	arg1	typology					1284:1291	the typology	1280:1291	the typology of its glyconjugates in response to temperature fluctuations	1280:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	5	11	theme	C.	884:885	arg1	34H					903:905	C. psychrerythraea 34H	884:905	C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	884:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	0	12	theme	Growth	114:119	arg1	Temperatures					121:132	Different Growth Temperatures	104:132	Different Growth Temperatures	104:132	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	7	13	theme	C.	1102:1103	arg1	34H					1121:1123	C. psychrerythraea 34H	1102:1123	C. psychrerythraea 34H	1102:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	6	14	theme	spectroscopic	1018:1030	arg1	analyses					1032:1039	spectroscopic analyses	1018:1039	spectroscopic analyses	1018:1039	The glycopolymers have been detected by chemical methods and spectroscopic analyses.					
35283851	5	15	theme	glycoconjugates	810:824	arg1	response					792:799	the response	788:799	the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	788:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	7	16	theme	biofilm	1084:1090	arg1	matrix					1092:1097	the biofilm matrix	1080:1097	the biofilm matrix of C. psychrerythraea 34H	1080:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	7	17	theme	glycosyl	1177:1184	arg1	analysis					1186:1193	glycosyl analysis	1177:1193	glycosyl analysis	1177:1193	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	4	18	theme	unusual	668:674	arg1	molecule					696:703	an unusual lipooligosaccharide molecule	665:703	an unusual lipooligosaccharide molecule	665:703	It produces an unusual lipooligosaccharide molecule and both capsular and medium released polysaccharides.					
35283851	2	19	theme	studies	453:459	arg1	lifestyle					411:419	its lifestyle	407:419	its lifestyle	407:419	This microorganism is considered a model to study adaptive strategies to sub-zero temperatures, and its lifestyle has been the object of numerous studies.					
35283851	2	19	theme	studies	453:459	arg1	object					434:439	the object	430:439	the object of numerous studies	430:459	This microorganism is considered a model to study adaptive strategies to sub-zero temperatures, and its lifestyle has been the object of numerous studies.					
35283851	1	20	theme	cold	288:291	arg1	environments					293:304	cold environments	288:304	cold environments	288:304	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	7	21	theme	matrix	1092:1097	arg1	content					1069:1075	the glycopolymer content	1052:1075	the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H	1052:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	5	22	theme	psychrerythraea	887:901	arg1	34H					903:905	C. psychrerythraea 34H	884:905	C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	884:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	2	23	theme	numerous	444:451	arg1	studies					453:459	numerous studies	444:459	numerous studies	444:459	This microorganism is considered a model to study adaptive strategies to sub-zero temperatures, and its lifestyle has been the object of numerous studies.					
35283851	1	24	from	cosmopolitan	272:283	arg1	environments					293:304	cold environments	288:304	cold environments	288:304	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	3	25	theme	psychrerythraea	546:560	arg1	34H					562:564	C. psychrerythraea 34H	543:564	C. psychrerythraea 34H	543:564	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	8	26	from	response	1317:1324	arg1	production					1265:1274	the production	1261:1274	the production	1261:1274	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	8	26	from	response	1317:1324	arg1	typology					1284:1291	the typology	1280:1291	the typology of its glyconjugates in response to temperature fluctuations	1280:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	3	27	theme	last	469:472	arg1	years					478:482	the last few years	465:482	the last few years	465:482	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	0	28	theme	Extracellular	13:25	arg1	Matrix					27:32	Extracellular Matrix	13:32	Extracellular Matrix	13:32	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	3	29	theme	molecules	642:650	arg1	characterization					605:620	characterization	605:620	characterization	605:620	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	3	29	theme	molecules	642:650	arg1	isolation					591:599	isolation	591:599	isolation	591:599	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	4	30	dep	capsular	714:721	arg1	polysaccharides					743:757	released polysaccharides	734:757	released polysaccharides	734:757	It produces an unusual lipooligosaccharide molecule and both capsular and medium released polysaccharides.					
35283851	8	31	from	typology	1284:1291	arg1	response					1317:1324	response	1317:1324	response to temperature fluctuations	1317:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	3	32	theme	few	474:476	arg1	years					478:482	the last few years	465:482	the last few years	465:482	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	8	33	theme	C.	1225:1226	arg1	34H					1244:1246	C. psychrerythraea 34H	1225:1246	C. psychrerythraea 34H	1225:1246	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	7	34	theme	glycopolymer	1056:1067	arg1	content					1069:1075	the glycopolymer content	1052:1075	the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H	1052:1123	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	5	35	theme	chemical	853:860	arg1	structure					862:870	chemical structure	853:870	chemical structure	853:870	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	1	36	theme	Arctic	226:231	arg1	sediments					240:248	Arctic marine sediments	226:248	Arctic marine sediments	226:248	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	7	37	theme	confocal	1153:1160	arg1	microscopy					1162:1171	confocal microscopy	1153:1171	confocal microscopy	1153:1171	Moreover, the glycopolymer content of the biofilm matrix of C. psychrerythraea 34H has been evaluated, through confocal microscopy and glycosyl analysis.					
35283851	8	38	from	production	1265:1274	arg1	response					1317:1324	response	1317:1324	response to temperature fluctuations	1317:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	1	39	theme	marine	233:238	arg1	sediments					240:248	Arctic marine sediments	226:248	Arctic marine sediments	226:248	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	0	40	theme	psychrerythraea	61:75	arg1	34H					77:79	Colwellia psychrerythraea 34H	51:79	Colwellia psychrerythraea 34H	51:79	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	3	41	theme	interesting	630:640	arg1	molecules					642:650	very interesting molecules	625:650	very interesting molecules	625:650	In the last few years, we focused our studies on the glycoconjugates produced by C. psychrerythraea 34H at 4°C, resulting in the isolation and characterization of very interesting molecules.					
35283851	2	42	theme	adaptive	357:364	arg1	strategies					366:375	adaptive strategies	357:375	adaptive strategies to sub-zero temperatures	357:400	This microorganism is considered a model to study adaptive strategies to sub-zero temperatures, and its lifestyle has been the object of numerous studies.					
35283851	0	43	theme	Colwellia	51:59	arg1	34H					77:79	Colwellia psychrerythraea 34H	51:79	Colwellia psychrerythraea 34H	51:79	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	0	44	from	Temperatures	121:132	arg1	Changes					93:99	Structural Changes	82:99	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.	0:133	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	1	45	theme	Colwellia	135:143	arg1	psychrophile					191:202	psychrophile	191:202	psychrophile	191:202	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	1	45	theme	Colwellia	135:143	arg1	34H					161:163	Colwellia psychrerythraea 34H	135:163	Colwellia psychrerythraea 34H	135:163	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	1	46	attach	isolated	212:219	arg1	sediments					240:248	Arctic marine sediments	226:248	Arctic marine sediments	226:248	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	1	46	attach	isolated	212:219	arg2	it					205:206	it	205:206	it	205:206	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	1	47	theme	psychrerythraea	145:159	arg1	psychrophile					191:202	psychrophile	191:202	psychrophile	191:202	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	1	47	theme	psychrerythraea	145:159	arg1	34H					161:163	Colwellia psychrerythraea 34H	135:163	Colwellia psychrerythraea 34H	135:163	Colwellia psychrerythraea 34H is a marine Gram-negative psychrophile; it was isolated from Arctic marine sediments, but it is considered cosmopolitan in cold environments.					
35283851	4	48	theme	lipooligosaccharide	676:694	arg1	molecule					696:703	an unusual lipooligosaccharide molecule	665:703	an unusual lipooligosaccharide molecule	665:703	It produces an unusual lipooligosaccharide molecule and both capsular and medium released polysaccharides.					
35283851	4	49	theme	released	734:741	arg1	polysaccharides					743:757	released polysaccharides	734:757	released polysaccharides	734:757	It produces an unusual lipooligosaccharide molecule and both capsular and medium released polysaccharides.					
35283851	5	50	theme	structure	862:870	arg1	terms					829:833	terms	829:833	terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	829:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	5	51	theme	production	838:847	arg1	terms					829:833	terms	829:833	terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C	829:954	In this study, we described the response of these glycoconjugates in terms of production and chemical structure produced by C. psychrerythraea 34H grown in planktonic conditions at -2, 4, and 8°C.					
35283851	8	52	theme	temperature	1329:1339	arg1	fluctuations					1341:1352	temperature fluctuations	1329:1352	temperature fluctuations	1329:1352	The results highlighted that C. psychrerythraea 34H adjusts both the production and the typology of its glyconjugates in response to temperature fluctuations.					
35283851	0	53	theme	34H	77:79	arg1	Membrane					0:7	Membrane	0:7	Membrane	0:7	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	0	53	theme	34H	77:79	arg1	Matrix					27:32	Extracellular Matrix	13:32	Extracellular Matrix	13:32	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	0	54	dep	Membrane	0:7	arg1	Changes					93:99	Structural Changes	82:99	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.	0:133	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	0	54	dep	Membrane	0:7	arg1	Glycopolymers					34:46	Glycopolymers	34:46	Glycopolymers	34:46	Membrane and Extracellular Matrix Glycopolymers of Colwellia psychrerythraea 34H: Structural Changes at Different Growth Temperatures.					
35283851	2	55	theme	sub-zero	380:387	arg1	temperatures					389:400	sub-zero temperatures	380:400	sub-zero temperatures	380:400	This microorganism is considered a model to study adaptive strategies to sub-zero temperatures, and its lifestyle has been the object of numerous studies.					
36076398	4	0	theme	microscope	770:779	arg1	analyses					787:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses	718:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses	718:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	1	1	theme	composite	233:241	arg1	particles					243:251	composite particles	233:251	composite particles of proteins with chitosan (CS)	233:282	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	0	2	theme	carrier	85:91	arg1	mechanism					108:116	a novel carrier: Self-assembly mechanism	77:116	a novel carrier: Self-assembly mechanism	77:116	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	2	theme	carrier	85:91	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	7	3	theme	water-insoluble	1350:1364	arg1	supplements					1378:1388	water-insoluble nutritional supplements	1350:1388	water-insoluble nutritional supplements	1350:1388	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	4	4	theme	force	764:768	arg1	microscope					770:779	atomic force microscope	757:779	atomic force microscope (AFM)	757:785	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	4	theme	force	764:768	arg1	AFM					782:784	AFM	782:784	AFM	782:784	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	5	theme	shell	843:847	arg1	morphology					849:858	a soft core-rigid shell morphology	825:858	a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions	825:943	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	7	6	theme	nutritional	1366:1376	arg1	supplements					1378:1388	water-insoluble nutritional supplements	1350:1388	water-insoluble nutritional supplements	1350:1388	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	0	7	theme	Self-assembly	94:106	arg1	mechanism					108:116	a novel carrier: Self-assembly mechanism	77:116	a novel carrier: Self-assembly mechanism	77:116	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	7	theme	Self-assembly	94:106	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	5	8	theme	binding	1013:1019	arg1	constant					1021:1028	a higher binding constant	1004:1028	a higher binding constant (K, 1.69 ×104 M-1)	1004:1047	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	4	9	theme	hydrophobic	895:905	arg1	interactions					907:918	hydrophobic interactions	895:918	hydrophobic interactions	895:918	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	1	10	theme	proteins	256:263	arg1	protein					205:211	succinylated whey protein	187:211	succinylated whey protein	187:211	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	10	theme	proteins	256:263	arg1	WPI					179:181	WPI	179:181	WPI	179:181	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	10	theme	proteins	256:263	arg1	isolate					170:176	Single protein [whey protein isolate	141:176	Single protein [whey protein isolate (WPI)	141:182	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	10	theme	proteins	256:263	arg1	SWPI					222:225	SWPI	222:225	SWPI	222:225	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	10	theme	proteins	256:263	arg1	particles					243:251	composite particles	233:251	composite particles of proteins with chitosan (CS)	233:282	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	0	11	theme	stability	122:130	arg1	studies					132:138	stability studies	122:138	stability studies	122:138	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	11	theme	stability	122:130	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	3	12	theme	circular	664:671	arg1	CD					684:685	CD	684:685	CD	684:685	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	3	12	theme	circular	664:671	arg1	dichroism					673:681	circular dichroism	664:681	circular dichroism (CD)	664:686	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	6	13	theme	steric	1141:1146	arg1	hindrance					1148:1156	steric hindrance	1141:1156	steric hindrance	1141:1156	Because of increased binding sites and steric hindrance, CUR was stabilized more effectively in H-CS in photostability and thermostability tests,.					
36076398	7	14	used	utilized	1308:1315	arg2	particles					1291:1299	SWPI-CS composite particles	1273:1299	SWPI-CS composite particles	1273:1299	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	5	15	theme	CUR	1097:1099	arg1	effectiveness					1067:1079	encapsulation effectiveness	1053:1079	encapsulation effectiveness	1053:1079	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	15	theme	CUR	1097:1099	arg1	constant					1021:1028	a higher binding constant	1004:1028	a higher binding constant (K, 1.69 ×104 M-1)	1004:1047	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	4	16	theme	H-bond	925:930	arg1	interactions					932:943	H-bond interactions	925:943	H-bond interactions	925:943	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	2	17	theme	high	476:479	arg1	degree					481:486	high degree	476:486	high degree of succinylation	476:503	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	0	18	theme	whey	13:16	arg1	protein					18:24	Succinylated whey protein	0:24	Succinylated whey protein	0:24	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	7	19	theme	protection	1328:1337	arg1	system					1339:1344	a protection system	1326:1344	a protection system for water-insoluble nutritional supplements	1326:1388	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	4	20	theme	atomic	757:762	arg1	microscope					770:779	atomic force microscope	757:779	atomic force microscope (AFM)	757:785	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	20	theme	atomic	757:762	arg1	AFM					782:784	AFM	782:784	AFM	782:784	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	0	21	theme	novel	79:83	arg1	mechanism					108:116	a novel carrier: Self-assembly mechanism	77:116	a novel carrier: Self-assembly mechanism	77:116	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	21	theme	novel	79:83	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	1	22	dep	isolate	170:176	arg1	isolate					213:219	isolate	213:219	isolate	213:219	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	0	23	theme	Succinylated	0:11	arg1	protein					18:24	Succinylated whey protein	0:24	Succinylated whey protein	0:24	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	3	24	dep	Fourier	629:635	arg1	transform					637:645	transform	637:645	transform infrared	637:654	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	6	25	theme	binding	1123:1129	arg1	sites					1131:1135	increased binding sites	1113:1135	increased binding sites	1113:1135	Because of increased binding sites and steric hindrance, CUR was stabilized more effectively in H-CS in photostability and thermostability tests,.					
36076398	1	26	theme	succinylated	187:198	arg1	protein					205:211	succinylated whey protein	187:211	succinylated whey protein	187:211	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	5	27	contain	had	1000:1002	arg2	effectiveness					1067:1079	encapsulation effectiveness	1053:1079	encapsulation effectiveness	1053:1079	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	27	contain	had	1000:1002	arg2	constant					1021:1028	a higher binding constant	1004:1028	a higher binding constant (K, 1.69 ×104 M-1)	1004:1047	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	27	contain	had	1000:1002	arg1	H-CS					995:998	H-CS	995:998	H-CS	995:998	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	3	28	dep	transform	637:645	arg1	infrared					647:654	infrared	647:654	transform infrared	637:654	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	5	29	theme	Fluorescence	946:957	arg1	results					969:975	Fluorescence quenching results	946:975	Fluorescence quenching results	946:975	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	7	30	theme	SWPI-CS	1273:1279	arg1	particles					1291:1299	SWPI-CS composite particles	1273:1299	SWPI-CS composite particles	1273:1299	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	6	31	theme	increased	1113:1121	arg1	sites					1131:1135	increased binding sites	1113:1135	increased binding sites	1113:1135	Because of increased binding sites and steric hindrance, CUR was stabilized more effectively in H-CS in photostability and thermostability tests,.					
36076398	1	32	theme	whey	200:203	arg1	protein					205:211	succinylated whey protein	187:211	succinylated whey protein	187:211	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	3	33	theme	tertiary	577:584	arg1	structures					586:595	the secondary and tertiary structures	559:595	the secondary and tertiary structures	559:595	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	7	34	theme	composite	1281:1289	arg1	particles					1291:1299	SWPI-CS composite particles	1273:1299	SWPI-CS composite particles	1273:1299	These results show that SWPI-CS composite particles can be utilized to build a protection system for water-insoluble nutritional supplements.					
36076398	4	35	theme	electrostatic	867:879	arg1	interactions					881:892	electrostatic interactions	867:892	electrostatic interactions	867:892	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	0	36	theme	composite	54:62	arg1	mechanism					108:116	a novel carrier: Self-assembly mechanism	77:116	a novel carrier: Self-assembly mechanism	77:116	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	36	theme	composite	54:62	arg1	studies					132:138	stability studies	122:138	stability studies	122:138	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	36	theme	composite	54:62	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	4	37	theme	soft	827:830	arg1	morphology					849:858	a soft core-rigid shell morphology	825:858	a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions	825:943	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	38	theme	electron	727:734	arg1	SEM					748:750	SEM	748:750	SEM	748:750	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	38	theme	electron	727:734	arg1	microscopy					736:745	Scanning electron microscopy	718:745	Scanning electron microscopy (SEM)	718:751	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	0	39	theme	core-shell	43:52	arg1	mechanism					108:116	a novel carrier: Self-assembly mechanism	77:116	a novel carrier: Self-assembly mechanism	77:116	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	39	theme	core-shell	43:52	arg1	studies					132:138	stability studies	122:138	stability studies	122:138	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	0	39	theme	core-shell	43:52	arg1	particles					64:72	core-shell composite particles	43:72	core-shell composite particles	43:72	Succinylated whey protein isolate-chitosan core-shell composite particles as a novel carrier: Self-assembly mechanism and stability studies.					
36076398	3	40	theme	X-ray	693:697	arg1	XRD					712:714	XRD	712:714	XRD	712:714	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	3	40	theme	X-ray	693:697	arg1	diffraction					699:709	X-ray diffraction	693:709	X-ray diffraction (XRD)	693:715	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	2	41	theme	succinylation	491:503	arg1	degree					481:486	high degree	476:486	high degree of succinylation	476:503	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	3	42	theme	secondary	563:571	arg1	structures					586:595	the secondary and tertiary structures	559:595	the secondary and tertiary structures	559:595	Furthermore, the secondary and tertiary structures were dramatically altered using Fourier transform infrared (FTIR), circular dichroism (CD), and X-ray diffraction (XRD).					
36076398	4	43	theme	Scanning	718:725	arg1	SEM					748:750	SEM	748:750	SEM	748:750	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	43	theme	Scanning	718:725	arg1	microscopy					736:745	Scanning electron microscopy	718:745	Scanning electron microscopy (SEM)	718:751	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	2	44	theme	surface	424:430	arg1	hydrophobicity					432:445	surface hydrophobicity	424:445	surface hydrophobicity	424:445	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	2	45	theme	composite	519:527	arg1	H-CS					539:542	H-CS	539:542	H-CS	539:542	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	2	45	theme	composite	519:527	arg1	particle					529:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle	464:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS)	464:543	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	5	46	theme	higher	1006:1011	arg1	constant					1021:1028	a higher binding constant	1004:1028	a higher binding constant (K, 1.69 ×104 M-1)	1004:1047	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	1	47	with	proteins	256:263	arg1	CS					280:281	CS	280:281	CS	280:281	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	47	with	proteins	256:263	arg1	chitosan					270:277	chitosan	270:277	chitosan (CS)	270:282	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	6	48	dep	photostability	1206:1219	arg1	tests					1241:1245	tests	1241:1245	tests	1241:1245	Because of increased binding sites and steric hindrance, CUR was stabilized more effectively in H-CS in photostability and thermostability tests,.					
36076398	2	49	dep	degree	481:486	arg1	%					509:509	90 %	506:509	90 %	506:509	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	5	50	theme	encapsulation	1053:1065	arg1	effectiveness					1067:1079	encapsulation effectiveness	1053:1079	encapsulation effectiveness	1053:1079	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	2	51	theme	CS	516:517	arg1	H-CS					539:542	H-CS	539:542	H-CS	539:542	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	2	51	theme	CS	516:517	arg1	particle					529:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle	464:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS)	464:543	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	5	52	theme	quenching	959:967	arg1	results					969:975	Fluorescence quenching results	946:975	Fluorescence quenching results	946:975	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	4	53	theme	microscopy	736:745	arg1	analyses					787:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses	718:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses	718:794	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	4	54	theme	due	860:862	arg1	morphology					849:858	a soft core-rigid shell morphology	825:858	a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions	825:943	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36076398	5	55	dep	constant	1021:1028	arg1	EE					1082:1083	EE	1082:1083	EE	1082:1083	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	55	dep	constant	1021:1028	arg1	%					1091:1091	88.3 %	1086:1091	88.3 %	1086:1091	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	55	dep	constant	1021:1028	arg1	K					1031:1031	K	1031:1031	K	1031:1031	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	5	55	dep	constant	1021:1028	arg1	M-1					1044:1046	1.69 ×104 M-1	1034:1046	1.69 ×104 M-1	1034:1046	Fluorescence quenching results demonstrated that H-CS had a higher binding constant (K, 1.69 ×104 M-1) and encapsulation effectiveness (EE, 88.3 %) of CUR.					
36076398	2	56	dep	SWPI-H	468:473	arg1	degree					481:486	high degree	476:486	high degree of succinylation	476:503	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	1	57	theme	Single	141:146	arg1	WPI					179:181	WPI	179:181	WPI	179:181	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	57	theme	Single	141:146	arg1	isolate					170:176	Single protein [whey protein isolate	141:176	Single protein [whey protein isolate (WPI)	141:182	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	57	theme	Single	141:146	arg1	SWPI					222:225	SWPI	222:225	SWPI	222:225	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	58	theme	protein	148:154	arg1	WPI					179:181	WPI	179:181	WPI	179:181	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	58	theme	protein	148:154	arg1	isolate					170:176	Single protein [whey protein isolate	141:176	Single protein [whey protein isolate (WPI)	141:182	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	58	theme	protein	148:154	arg1	SWPI					222:225	SWPI	222:225	SWPI	222:225	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	2	59	theme	SWPI-H	468:473	arg1	H-CS					539:542	H-CS	539:542	H-CS	539:542	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	2	59	theme	SWPI-H	468:473	arg1	particle					529:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle	464:536	the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS)	464:543	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	1	60	theme	[whey	156:160	arg1	WPI					179:181	WPI	179:181	WPI	179:181	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	60	theme	[whey	156:160	arg1	isolate					170:176	Single protein [whey protein isolate	141:176	Single protein [whey protein isolate (WPI)	141:182	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	60	theme	[whey	156:160	arg1	SWPI					222:225	SWPI	222:225	SWPI	222:225	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	2	61	from	changes	394:400	arg1	zeta-potential					405:418	zeta-potential	405:418	zeta-potential	405:418	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	2	61	from	changes	394:400	arg1	hydrophobicity					432:445	surface hydrophobicity	424:445	surface hydrophobicity	424:445	Combining protein and CS resulted in changes in zeta-potential and surface hydrophobicity, particularly in the SWPI-H (high degree of succinylation, 90 %) and CS composite particle (H-CS).					
36076398	1	62	theme	protein	162:168	arg1	WPI					179:181	WPI	179:181	WPI	179:181	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	62	theme	protein	162:168	arg1	isolate					170:176	Single protein [whey protein isolate	141:176	Single protein [whey protein isolate (WPI)	141:182	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	1	62	theme	protein	162:168	arg1	SWPI					222:225	SWPI	222:225	SWPI	222:225	Single protein [whey protein isolate (WPI) or succinylated whey protein isolate (SWPI)] and composite particles of proteins with chitosan (CS) were tested for their ability to encapsulate and protect curcumin (CUR).					
36076398	4	63	theme	core-rigid	832:841	arg1	morphology					849:858	a soft core-rigid shell morphology	825:858	a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions	825:943	Scanning electron microscopy (SEM) and atomic force microscope (AFM) analyses revealed that H-CS exhibited a soft core-rigid shell morphology due to electrostatic interactions, hydrophobic interactions, and H-bond interactions.					
36990404	2	0	theme	stents	510:515	arg1	endothelialization					440:457	insufficient endothelialization	427:457	insufficient endothelialization	427:457	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	2	0	theme	stents	510:515	arg1	resistance					478:487	poor corrosion resistance	463:487	poor corrosion resistance	463:487	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	6	1	theme	promising	1233:1241	arg1	strategy					1256:1263	a promising and feasible strategy	1231:1263	a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents	1231:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	5	2	theme	@	1089:1089	arg1	coating					1101:1107	current clinical PLLA@ Rapamycin coating	1068:1107	current clinical PLLA@ Rapamycin coating	1068:1107	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	4	3	theme	anti-inflammatory	1027:1043	arg1	functions					1045:1053	anti-inflammatory functions	1027:1053	anti-inflammatory functions	1027:1053	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	2	4	theme	vascular	501:508	arg1	stents					510:515	Mg alloy vascular stents	492:515	Mg alloy vascular stents	492:515	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	3	5	theme	sulfonated	667:676	arg1	acid					689:692	sulfonated hyaluronic acid	667:692	sulfonated hyaluronic acid (S-HA)	667:699	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	5	theme	sulfonated	667:676	arg1	S-HA					695:698	S-HA	695:698	S-HA	695:698	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	4	6	contain	had	959:961	arg2	pro-endothelial					989:1003	pro-endothelial	989:1003	pro-endothelial	989:1003	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	4	6	contain	had	959:961	arg2	compatibility					974:986	good blood compatibility	963:986	good blood compatibility	963:986	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	4	6	contain	had	959:961	arg1	coating					951:957	the composite coating	937:957	the composite coating	937:957	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	4	6	contain	had	959:961	arg2	anti-hyperplasia					1006:1021	anti-hyperplasia	1006:1021	anti-hyperplasia	1006:1021	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	4	6	contain	had	959:961	arg2	functions					1045:1053	anti-inflammatory functions	1027:1053	anti-inflammatory functions	1027:1053	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	2	7	theme	hybrid	363:368	arg1	coating					370:376	a multifunctional hybrid coating	345:376	a multifunctional hybrid coating	345:376	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	3	8	theme	poly-L-lactic	826:838	arg1	acid					840:843	poly-L-lactic acid	826:843	poly-L-lactic acid (PLLA) coating preparation by one-step pulling method	826:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	8	theme	poly-L-lactic	826:838	arg1	PLLA					846:849	PLLA	846:849	PLLA	846:849	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	9	theme	self-assembly	790:802	arg1	method					804:809	self-assembly method	790:809	self-assembly method	790:809	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	0	10	theme	sulfonated	84:93	arg1	acid					106:109	sulfonated hyaluronic acid	84:109	sulfonated hyaluronic acid	84:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	3	11	theme	hyaluronic	678:687	arg1	acid					689:692	sulfonated hyaluronic acid	667:692	sulfonated hyaluronic acid (S-HA)	667:699	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	11	theme	hyaluronic	678:687	arg1	S-HA					695:698	S-HA	695:698	S-HA	695:698	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	1	12	theme	cardiovascular	253:266	arg1	implants					268:275	cardiovascular implants	253:275	cardiovascular implants due to their good mechanical properties and biosafety	253:329	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	5	13	theme	current	1068:1074	arg1	coating					1101:1107	current clinical PLLA@ Rapamycin coating	1068:1107	current clinical PLLA@ Rapamycin coating	1068:1107	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	6	14	theme	feasible	1247:1254	arg1	strategy					1256:1263	a promising and feasible strategy	1231:1263	a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents	1231:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	3	15	theme	magnesium	550:558	arg1	MgF2					570:573	MgF2	570:573	MgF2	570:573	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	15	theme	magnesium	550:558	arg1	fluoride					560:567	magnesium fluoride	550:567	magnesium fluoride (MgF2)	550:574	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	4	16	theme	composite	941:949	arg1	coating					951:957	the composite coating	937:957	the composite coating	937:957	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	1	17	theme	implants	268:275	arg1	field					244:248	the field	240:248	the field of cardiovascular implants due to their good mechanical properties and biosafety	240:329	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	4	18	theme	cell	914:917	arg1	tests					919:923	The blood and cell tests	900:923	tests	919:923	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	5	19	theme	clinical	1076:1083	arg1	coating					1101:1107	current clinical PLLA@ Rapamycin coating	1068:1107	current clinical PLLA@ Rapamycin coating	1068:1107	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	3	20	theme	dense	535:539	arg1	layer					541:545	a dense layer	533:545	a dense layer of magnesium fluoride (MgF2)	533:574	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	0	21	theme	hyaluronic	95:104	arg1	acid					106:109	sulfonated hyaluronic acid	84:109	sulfonated hyaluronic acid	84:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	5	22	theme	PLLA	1085:1088	arg1	coating					1101:1107	current clinical PLLA@ Rapamycin coating	1068:1107	current clinical PLLA@ Rapamycin coating	1068:1107	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	0	23	theme	alloy	48:52	arg1	modification					8:19	Surface modification	0:19	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid	0:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	2	24	theme	poor	463:466	arg1	resistance					478:487	poor corrosion resistance	463:487	poor corrosion resistance	463:487	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	2	25	theme	effective	393:401	arg1	strategy					403:410	an effective strategy	390:410	an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents	390:515	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	2	26	theme	corrosion	468:476	arg1	resistance					478:487	poor corrosion resistance	463:487	poor corrosion resistance	463:487	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	3	27	theme	small	715:719	arg1	NP					742:743	NP	742:743	NP	742:743	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	27	theme	small	715:719	arg1	nanoparticles					727:739	small sized nanoparticles	715:739	small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method	715:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	28	theme	sized	721:725	arg1	NP					742:743	NP	742:743	NP	742:743	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	28	theme	sized	721:725	arg1	nanoparticles					727:739	small sized nanoparticles	715:739	small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method	715:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	6	29	mod	modification	1281:1292	arg3	surface					1273:1279	the surface modification	1269:1292	the surface modification of Mg-based degradable cardiovascular stents	1269:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	6	29	mod	modification	1281:1292	arg1	stents					1332:1337	Mg-based degradable cardiovascular stents	1297:1337	Mg-based degradable cardiovascular stents	1297:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	0	30	theme	Surface	0:6	arg1	modification					8:19	Surface modification	0:19	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid	0:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	1	31	theme	due	277:279	arg1	implants					268:275	cardiovascular implants	253:275	cardiovascular implants due to their good mechanical properties and biosafety	253:329	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	4	32	theme	blood	968:972	arg1	compatibility					974:986	good blood compatibility	963:986	good blood compatibility	963:986	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	3	33	dep	deposited	757:765	arg1	followed					812:819	followed	812:819	followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method	812:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	0	34	theme	biodegradable	24:36	arg1	alloy					48:52	biodegradable magnesium alloy	24:52	biodegradable magnesium alloy	24:52	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	5	35	theme	better	1142:1147	arg1	functions					1149:1157	better functions	1142:1157	better functions of promoting endothelial cells growth	1142:1195	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	3	36	theme	fluoride	560:567	arg1	layer					541:545	a dense layer	533:545	a dense layer of magnesium fluoride (MgF2)	533:574	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	2	37	theme	insufficient	427:438	arg1	endothelialization					440:457	insufficient endothelialization	427:457	insufficient endothelialization	427:457	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	6	38	theme	stents	1332:1337	arg1	modification					1281:1292	the surface modification	1269:1292	the surface modification of Mg-based degradable cardiovascular stents	1269:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	3	39	theme	better	626:631	arg1	resistance					643:652	better corrosion resistance	626:652	better corrosion resistance	626:652	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	40	theme	one-step	875:882	arg1	method					892:897	one-step pulling method	875:897	one-step pulling method	875:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	2	41	theme	alloy	495:499	arg1	stents					510:515	Mg alloy vascular stents	492:515	Mg alloy vascular stents	492:515	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	1	42	theme	good	290:293	arg1	properties					306:315	their good mechanical properties	284:315	their good mechanical properties	284:315	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	6	43	theme	cardiovascular	1317:1330	arg1	stents					1332:1337	Mg-based degradable cardiovascular stents	1297:1337	Mg-based degradable cardiovascular stents	1297:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	3	44	theme	corrosion	633:641	arg1	resistance					643:652	better corrosion resistance	626:652	better corrosion resistance	626:652	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	3	45	theme	pulling	884:890	arg1	method					892:897	one-step pulling method	875:897	one-step pulling method	875:897	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	1	46	theme	extensive	202:210	arg1	attention					212:220	extensive attention	202:220	extensive attention of researchers	202:235	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	2	47	theme	Mg	492:493	arg1	stents					510:515	Mg alloy vascular stents	492:515	Mg alloy vascular stents	492:515	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	1	48	theme	mechanical	295:304	arg1	properties					306:315	their good mechanical properties	284:315	their good mechanical properties	284:315	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	0	49	theme	magnesium	38:46	arg1	alloy					48:52	biodegradable magnesium alloy	24:52	biodegradable magnesium alloy	24:52	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	5	50	theme	endothelial	1172:1182	arg1	growth					1190:1195	endothelial cells growth	1172:1195	endothelial cells growth	1172:1195	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	4	51	theme	good	963:966	arg1	compatibility					974:986	good blood compatibility	963:986	good blood compatibility	963:986	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	4	52	theme	blood	904:908	arg1	tests					919:923	The blood and cell tests	900:923	tests	919:923	The blood and cell tests showed that the composite coating had good blood compatibility, pro-endothelial, anti-hyperplasia and anti-inflammatory functions.					
36990404	6	53	theme	Mg-based	1297:1304	arg1	stents					1332:1337	Mg-based degradable cardiovascular stents	1297:1337	Mg-based degradable cardiovascular stents	1297:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	2	54	theme	multifunctional	347:361	arg1	coating					370:376	a multifunctional hybrid coating	345:376	a multifunctional hybrid coating	345:376	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	0	55	theme	cardiovascular	129:142	arg1	application					144:154	cardiovascular application	129:154	cardiovascular application	129:154	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	5	56	theme	S-HA	1122:1125	arg1	coating					1127:1133	our PLLA/NP@S-HA coating	1110:1133	our PLLA/NP@S-HA coating	1110:1133	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	2	57	dep	endothelialization	440:457	arg1	the					423:425	the	423:425	the	423:425	Constructing a multifunctional hybrid coating seems to be an effective strategy to address the insufficient endothelialization and poor corrosion resistance of Mg alloy vascular stents.					
36990404	0	58	with	modification	8:19	arg1	acid					74:77	L-lactic acid	65:77	L-lactic acid	65:77	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	0	58	with	modification	8:19	arg1	poly					59:62	poly	59:62	poly (L-lactic acid)	59:78	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	0	58	with	modification	8:19	arg1	acid					106:109	sulfonated hyaluronic acid	84:109	sulfonated hyaluronic acid	84:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	5	59	theme	PLLA/NP	1114:1120	arg1	coating					1127:1133	our PLLA/NP@S-HA coating	1110:1133	our PLLA/NP@S-HA coating	1110:1133	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	0	60	mod	modification	8:19	arg3	Surface					0:6	Surface modification	0:19	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid	0:109	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	0	60	mod	modification	8:19	arg1	alloy					48:52	biodegradable magnesium alloy	24:52	biodegradable magnesium alloy	24:52	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	3	61	theme	Mg	607:608	arg1	alloy					610:614	Mg alloy	607:614	Mg alloy aiming at better corrosion resistance	607:652	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	6	62	theme	degradable	1306:1315	arg1	stents					1332:1337	Mg-based degradable cardiovascular stents	1297:1337	Mg-based degradable cardiovascular stents	1297:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	6	63	theme	surface	1273:1279	arg1	modification					1281:1292	the surface modification	1269:1292	the surface modification of Mg-based degradable cardiovascular stents	1269:1337	These results strongly furnished a promising and feasible strategy for the surface modification of Mg-based degradable cardiovascular stents.					
36990404	3	64	theme	alloy	610:614	arg1	surface					596:602	the surface	592:602	the surface of Mg alloy aiming at better corrosion resistance	592:652	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	1	65	theme	researchers	225:235	arg1	attention					212:220	extensive attention	202:220	extensive attention of researchers	202:235	Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cardiovascular implants due to their good mechanical properties and biosafety.					
36990404	0	66	theme	L-lactic	65:72	arg1	acid					74:77	L-lactic acid	65:77	L-lactic acid	65:77	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	0	66	theme	L-lactic	65:72	arg1	poly					59:62	poly	59:62	poly (L-lactic acid)	59:78	Surface modification of biodegradable magnesium alloy with poly (L-lactic acid) and sulfonated hyaluronic acid nanoparticles for cardiovascular application.					
36990404	3	67	theme	MgF2	774:777	arg1	surface					779:785	the MgF2 surface	770:785	the MgF2 surface	770:785	In this study, a dense layer of magnesium fluoride (MgF2) was prepared on the surface of Mg alloy aiming at better corrosion resistance; Thereafter, sulfonated hyaluronic acid (S-HA) was made into small sized nanoparticles (NP) which were deposited on the MgF2 surface by self-assembly method, followed with poly-L-lactic acid (PLLA) coating preparation by one-step pulling method.					
36990404	5	68	theme	Rapamycin	1091:1099	arg1	coating					1101:1107	current clinical PLLA@ Rapamycin coating	1068:1107	current clinical PLLA@ Rapamycin coating	1068:1107	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	5	69	theme	cells	1184:1188	arg1	growth					1190:1195	endothelial cells growth	1172:1195	endothelial cells growth	1172:1195	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36990404	5	70	theme	@	1121:1121	arg1	coating					1127:1133	our PLLA/NP@S-HA coating	1110:1133	our PLLA/NP@S-HA coating	1110:1133	Compared to current clinical PLLA@ Rapamycin coating, our PLLA/NP@S-HA coating showed better functions of promoting endothelial cells growth.					
36889107	0	0	theme	wound	93:97	arg1	healing					99:105	wound healing	93:105	wound healing	93:105	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	3	1	theme	alginate/carbon	329:343	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	1	theme	alginate/carbon	329:343	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	7	2	dep	In	864:865	arg1	vitro					867:871	vitro	867:871	vitro	867:871	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	3	3	theme	polymer	345:351	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	3	theme	polymer	345:351	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	7	4	dep	in	877:878	arg1	vivo					880:883	vivo	880:883	vivo	880:883	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	8	5	theme	wounds	1163:1168	arg1	application					1135:1145	the clinical application	1122:1145	the clinical application of high-exudate wounds	1122:1168	Moreover, its good hygroscopicity and antioxidation characteristics were friendly for the clinical application of high-exudate wounds.					
36889107	5	6	theme	CA/CPDs/FT	637:646	arg1	membranes					648:656	CA/CPDs/FT membranes	637:656	CA/CPDs/FT membranes	637:656	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	4	7	theme	membrane	617:624	arg1	strength					591:598	the mechanical strength	576:598	the mechanical strength of the composite membrane	576:624	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	8	8	theme	clinical	1126:1133	arg1	application					1135:1145	the clinical application	1122:1145	the clinical application of high-exudate wounds	1122:1168	Moreover, its good hygroscopicity and antioxidation characteristics were friendly for the clinical application of high-exudate wounds.					
36889107	4	9	theme	polymer	506:512	arg1	dots					514:517	carbon polymer dots	499:517	carbon polymer dots	499:517	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	5	10	theme	natural	737:743	arg1	properties					745:754	the natural properties	733:754	the natural properties of forsythin	733:767	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	7	11	theme	wound	1021:1025	arg1	healing					1027:1033	wound healing	1021:1033	wound healing	1021:1033	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	7	12	theme	nanofibrous	924:934	arg1	membrane					936:943	the CA/CPDs/FT nanofibrous membrane	909:943	the CA/CPDs/FT nanofibrous membrane	909:943	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	3	13	theme	nanofibrous	378:388	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	13	theme	nanofibrous	378:388	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	0	14	from	base	59:62	arg1	alginate					67:74	alginate	67:74	alginate	67:74	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	5	15	theme	antibacterial	681:693	arg1	properties					711:720	satisfactory antibacterial and antioxidant properties	668:720	satisfactory antibacterial and antioxidant properties	668:720	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	5	16	theme	satisfactory	668:679	arg1	properties					711:720	satisfactory antibacterial and antioxidant properties	668:720	satisfactory antibacterial and antioxidant properties	668:720	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	6	17	theme	outstanding	781:791	arg1	Meanwhile					770:778	Meanwhile	770:778	Meanwhile	770:778	Meanwhile, outstanding hygroscopicity over 700% was also obtained for the composite membrane.					
36889107	6	17	theme	outstanding	781:791	arg1	hygroscopicity					793:806	outstanding hygroscopicity	781:806	outstanding hygroscopicity over 700%	781:816	Meanwhile, outstanding hygroscopicity over 700% was also obtained for the composite membrane.					
36889107	1	18	theme	wound	168:172	arg1	healing					174:180	wound healing	168:180	wound healing	168:180	The removal of bacterium and free radicals is important for wound healing.					
36889107	4	19	theme	composite	607:615	arg1	membrane					617:624	the composite membrane	603:624	the composite membrane	603:624	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	8	20	theme	antioxidation	1074:1086	arg1	characteristics					1088:1102	antioxidation characteristics	1074:1102	antioxidation characteristics	1074:1102	Moreover, its good hygroscopicity and antioxidation characteristics were friendly for the clinical application of high-exudate wounds.					
36889107	7	21	theme	CA/CPDs/FT	913:922	arg1	membrane					936:943	the CA/CPDs/FT nanofibrous membrane	909:943	the CA/CPDs/FT nanofibrous membrane	909:943	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	3	22	theme	forsythin	472:480	arg1	influence					435:443	the influence	431:443	the influence of carbon polymer dots and forsythin	431:480	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	0	23	theme	hygroscopicity	7:20	arg1	base					59:62	Highly hygroscopicity and antioxidant nanofibrous dressing base	0:62	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.	0:106	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	4	24	theme	dots	514:517	arg1	addition					487:494	The addition	483:494	The addition of carbon polymer dots	483:517	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	5	25	theme	antioxidant	699:709	arg1	properties					711:720	satisfactory antibacterial and antioxidant properties	668:720	satisfactory antibacterial and antioxidant properties	668:720	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	4	26	theme	carbon	499:504	arg1	dots					514:517	carbon polymer dots	499:517	carbon polymer dots	499:517	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	3	27	theme	polymer	455:461	arg1	dots					463:466	carbon polymer dots	448:466	carbon polymer dots	448:466	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	7	28	theme	in	877:878	arg1	experiments					885:895	In vitro and in vivo experiments	864:895	In vitro and in vivo experiments	864:895	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	8	29	theme	high-exudate	1150:1161	arg1	wounds					1163:1168	high-exudate wounds	1150:1168	high-exudate wounds	1150:1168	Moreover, its good hygroscopicity and antioxidation characteristics were friendly for the clinical application of high-exudate wounds.					
36889107	3	30	theme	dots	463:466	arg1	influence					435:443	the influence	431:443	the influence of carbon polymer dots and forsythin	431:480	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	0	31	theme	antioxidant	26:36	arg1	base					59:62	Highly hygroscopicity and antioxidant nanofibrous dressing base	0:62	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.	0:106	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	6	32	theme	composite	844:852	arg1	membrane					854:861	the composite membrane	840:861	the composite membrane	840:861	Meanwhile, outstanding hygroscopicity over 700% was also obtained for the composite membrane.					
36889107	2	33	with	dressings	232:240	arg1	properties					277:286	antibacterial and antioxidant properties	247:286	antibacterial and antioxidant properties	247:286	Therefore, it is necessary to prepare biological dressings with antibacterial and antioxidant properties.					
36889107	0	34	theme	dressing	50:57	arg1	base					59:62	Highly hygroscopicity and antioxidant nanofibrous dressing base	0:62	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.	0:106	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	0	35	theme	nanofibrous	38:48	arg1	base					59:62	Highly hygroscopicity and antioxidant nanofibrous dressing base	0:62	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.	0:106	Highly hygroscopicity and antioxidant nanofibrous dressing base on alginate for accelerating wound healing.					
36889107	3	36	theme	carbon	448:453	arg1	dots					463:466	carbon polymer dots	448:466	carbon polymer dots	448:466	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	2	37	theme	biological	221:230	arg1	dressings					232:240	biological dressings	221:240	biological dressings with antibacterial and antioxidant properties	221:286	Therefore, it is necessary to prepare biological dressings with antibacterial and antioxidant properties.					
36889107	7	38	theme	In	864:865	arg1	experiments					885:895	In vitro and in vivo experiments	864:895	In vitro and in vivo experiments	864:895	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	3	39	theme	high-performance	304:319	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	39	theme	high-performance	304:319	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	4	40	theme	mechanical	580:589	arg1	strength					591:598	the mechanical strength	576:598	the mechanical strength of the composite membrane	576:624	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36889107	3	41	theme	calcium	321:327	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	41	theme	calcium	321:327	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	1	42	theme	bacterium	123:131	arg1	important					154:162	important	154:162	important	154:162	The removal of bacterium and free radicals is important for wound healing.					
36889107	1	42	theme	bacterium	123:131	arg1	removal					112:118	The removal	108:118	The removal of bacterium and free radicals	108:149	The removal of bacterium and free radicals is important for wound healing.					
36889107	5	43	theme	forsythin	759:767	arg1	properties					745:754	the natural properties	733:754	the natural properties of forsythin	733:767	Moreover, CA/CPDs/FT membranes displayed satisfactory antibacterial and antioxidant properties because of the natural properties of forsythin.					
36889107	2	44	theme	antioxidant	265:275	arg1	properties					277:286	antibacterial and antioxidant properties	247:286	antibacterial and antioxidant properties	247:286	Therefore, it is necessary to prepare biological dressings with antibacterial and antioxidant properties.					
36889107	8	45	theme	good	1050:1053	arg1	hygroscopicity					1055:1068	its good hygroscopicity	1046:1068	its good hygroscopicity	1046:1068	Moreover, its good hygroscopicity and antioxidation characteristics were friendly for the clinical application of high-exudate wounds.					
36889107	7	46	theme	free	994:997	arg1	radicals					999:1006	free radicals	994:1006	free radicals	994:1006	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	1	47	theme	free	137:140	arg1	radicals					142:149	free radicals	137:149	free radicals	137:149	The removal of bacterium and free radicals is important for wound healing.					
36889107	7	48	theme	bacteria	975:982	arg1	invasion					963:970	the invasion	959:970	the invasion of bacteria	959:982	In vitro and in vivo experiments showed that the CA/CPDs/FT nanofibrous membrane could prevent the invasion of bacteria, scavenge free radicals, and promote wound healing.					
36889107	3	49	theme	dots/forsythin	353:366	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	49	theme	dots/forsythin	353:366	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	2	50	theme	antibacterial	247:259	arg1	properties					277:286	antibacterial and antioxidant properties	247:286	antibacterial and antioxidant properties	247:286	Therefore, it is necessary to prepare biological dressings with antibacterial and antioxidant properties.					
36889107	1	51	theme	radicals	142:149	arg1	important					154:162	important	154:162	important	154:162	The removal of bacterium and free radicals is important for wound healing.					
36889107	1	51	theme	radicals	142:149	arg1	removal					112:118	The removal	108:118	The removal of bacterium and free radicals	108:149	The removal of bacterium and free radicals is important for wound healing.					
36889107	3	52	theme	composite	368:376	arg1	membrane					390:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane	304:397	high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT)	304:410	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	3	52	theme	composite	368:376	arg1	CA/CPDs/FT					400:409	CA/CPDs/FT	400:409	CA/CPDs/FT	400:409	In this study, high-performance calcium alginate/carbon polymer dots/forsythin composite nanofibrous membrane (CA/CPDs/FT) was explored under the influence of carbon polymer dots and forsythin.					
36889107	4	53	theme	nanofiber	532:540	arg1	morphology					542:551	the nanofiber morphology	528:551	the nanofiber morphology	528:551	The addition of carbon polymer dots improved the nanofiber morphology and therefore enhanced the mechanical strength of the composite membrane.					
36436607	8	0	theme	Cr	974:975	arg1	adsorption					1004:1013	chemical adsorption	995:1013	chemical adsorption	995:1013	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	8	0	theme	Cr	974:975	arg1	adsorption					960:969	the adsorption	956:969	the adsorption of Cr(VI) by FMCS-1	956:989	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	7	1	theme	single	826:831	arg1	layer					843:847	a single molecular layer	824:847	a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2	824:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	7	1	theme	single	826:831	arg1	FMCS-1					814:819	FMCS-1	814:819	FMCS-1	814:819	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	5	2	from	separation	673:682	arg1	water					697:701	water	697:701	water	697:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	8	3	theme	chemical	995:1002	arg1	adsorption					1004:1013	chemical adsorption	995:1013	chemical adsorption	995:1013	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	8	3	theme	chemical	995:1002	arg1	adsorption					960:969	the adsorption	956:969	the adsorption of Cr(VI) by FMCS-1	956:989	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	2	4	from	aggregation	273:283	arg1	treatment					319:327	water treatment	313:327	water treatment	313:327	However, there are problems such as easy aggregation and difficult separation in water treatment.					
36436607	7	5	from	pH = 2	912:917	arg1	capacity					885:892	a maximum adsorption capacity	864:892	a maximum adsorption capacity of 109.46 mg/g at pH = 2	864:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	10	6	theme	removal	1176:1182	arg1	percentage					1184:1193	the removal percentage	1172:1193	the removal percentage	1172:1193	The recycling experiments proved that the adsorbent can be reused and the removal percentage still reaches 50 % after 5 cycles.					
36436607	1	7	theme	superior	207:214	arg1	structure					221:229	superior pore structure	207:229	superior pore structure	207:229	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	5	8	theme	MOFs	687:690	arg1	separation					673:682	the difficult separation	659:682	the difficult separation of MOFs from water	659:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	7	9	theme	maximum	866:872	arg1	capacity					885:892	a maximum adsorption capacity	864:892	a maximum adsorption capacity of 109.46 mg/g at pH = 2	864:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	1	10	theme	pore	216:219	arg1	structure					221:229	superior pore structure	207:229	superior pore structure	207:229	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	11	11	theme	Cr	1336:1337	arg1	removal					1343:1349	Cr(VI) removal	1336:1349	Cr(VI) removal	1336:1349	This work expands the application of MOFs in water treatment and also provides an effective adsorbent for Cr(VI) removal.					
36436607	0	12	dep	Cr	86:87	arg1	VI					89:90	VI	89:90	VI	89:90	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	6	13	dep	Cr	735:736	arg1	VI					738:739	VI	738:739	VI	738:739	The removal potential of toxic Cr(VI) was tested by adsorption experiments.					
36436607	4	14	theme	chitosan	545:552	arg1	introduction					529:540	the introduction	525:540	the introduction of chitosan	525:552	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	8	15	dep	Cr	974:975	arg1	VI					977:978	VI	977:978	VI	977:978	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	7	16	theme	109.46 mg/g	897:907	arg1	capacity					885:892	a maximum adsorption capacity	864:892	a maximum adsorption capacity of 109.46 mg/g at pH = 2	864:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	0	17	theme	Cr	86:87	arg1	removal					75:81	the removal	71:81	the removal of Cr(VI) from wastewater	71:107	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	7	18	with	adsorbent	849:857	arg1	capacity					885:892	a maximum adsorption capacity	864:892	a maximum adsorption capacity of 109.46 mg/g at pH = 2	864:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	7	19	theme	adsorption	874:883	arg1	capacity					885:892	a maximum adsorption capacity	864:892	a maximum adsorption capacity of 109.46 mg/g at pH = 2	864:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	10	20	theme	recycling	1106:1114	arg1	experiments					1116:1126	The recycling experiments	1102:1126	The recycling experiments	1102:1126	The recycling experiments proved that the adsorbent can be reused and the removal percentage still reaches 50 % after 5 cycles.					
36436607	7	21	theme	isotherm	784:791	arg1	model					793:797	The isotherm model	780:797	The isotherm model	780:797	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	0	22	theme	magnetic	2:9	arg1	chitosan					23:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	2	23	from	separation	299:308	arg1	treatment					319:327	water treatment	313:327	water treatment	313:327	However, there are problems such as easy aggregation and difficult separation in water treatment.					
36436607	5	24	theme	magnetic	601:608	arg1	test					610:613	The magnetic test	597:613	The magnetic test manifested that Fe3O4	597:635	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	6	25	theme	Cr	735:736	arg1	potential					716:724	The removal potential	704:724	The removal potential of toxic Cr(VI)	704:740	The removal potential of toxic Cr(VI) was tested by adsorption experiments.					
36436607	9	26	theme	acid	1020:1023	arg1	test					1036:1039	The acid resistance test	1016:1039	The acid resistance test	1016:1039	The acid resistance test demonstrated that FMCS-1 can exist stably in acid solutions.					
36436607	0	27	theme	@	22:22	arg1	chitosan					23:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	4	28	theme	materials	503:511	arg1	characterization					454:469	structural characterization	443:469	structural characterization	443:469	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	4	28	theme	materials	503:511	arg1	analysis					487:494	performance analysis	475:494	performance analysis	475:494	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	1	29	used	used	156:159	arg2	MOFs					136:139	MOFs	136:139	MOFs	136:139	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	1	29	used	used	156:159	arg2	frameworks					124:133	Metal-organic frameworks	110:133	Metal-organic frameworks (MOFs)	110:140	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	9	30	theme	resistance	1025:1034	arg1	test					1036:1039	The acid resistance test	1016:1039	The acid resistance test	1016:1039	The acid resistance test demonstrated that FMCS-1 can exist stably in acid solutions.					
36436607	0	31	theme	MIL-125-NH2	11:21	arg1	chitosan					23:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan	0:30	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	5	32	theme	difficult	663:671	arg1	separation					673:682	the difficult separation	659:682	the difficult separation of MOFs from water	659:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	5	33	from	water	697:701	arg1	MOFs					687:690	MOFs	687:690	MOFs from water	687:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	5	33	from	water	697:701	arg1	separation					673:682	the difficult separation	659:682	the difficult separation of MOFs from water	659:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	4	34	theme	MOFs	591:594	arg1	stacking					579:586	the stacking	575:586	the stacking of MOFs	575:594	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	11	35	theme	water	1275:1279	arg1	treatment					1281:1289	water treatment	1275:1289	water treatment	1275:1289	This work expands the application of MOFs in water treatment and also provides an effective adsorbent for Cr(VI) removal.					
36436607	5	36	theme	separation	673:682	arg1	problem					648:654	the problem	644:654	the problem of the difficult separation of MOFs from water	644:701	The magnetic test manifested that Fe3O4 solved the problem of the difficult separation of MOFs from water.					
36436607	3	37	theme	composite	357:365	arg1	FMCS-1					381:386	FMCS-1	381:386	FMCS-1	381:386	In this study, we prepared composite microspheres (FMCS-1) by modifying MIL-125-NH2 with Fe3O4 and chitosan.					
36436607	3	37	theme	composite	357:365	arg1	microspheres					367:378	composite microspheres	357:378	composite microspheres (FMCS-1)	357:387	In this study, we prepared composite microspheres (FMCS-1) by modifying MIL-125-NH2 with Fe3O4 and chitosan.					
36436607	0	38	from	wastewater	98:107	arg1	removal					75:81	the removal	71:81	the removal of Cr(VI) from wastewater	71:107	A magnetic MIL-125-NH2@chitosan composite as a separable adsorbent for the removal of Cr(VI) from wastewater.					
36436607	11	39	theme	MOFs	1267:1270	arg1	application					1252:1262	the application	1248:1262	the application of MOFs in water treatment	1248:1289	This work expands the application of MOFs in water treatment and also provides an effective adsorbent for Cr(VI) removal.					
36436607	4	40	theme	performance	475:485	arg1	analysis					487:494	performance analysis	475:494	performance analysis	475:494	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	11	41	from	application	1252:1262	arg1	treatment					1281:1289	water treatment	1275:1289	water treatment	1275:1289	This work expands the application of MOFs in water treatment and also provides an effective adsorbent for Cr(VI) removal.					
36436607	2	42	theme	difficult	289:297	arg1	separation					299:308	difficult separation	289:308	difficult separation	289:308	However, there are problems such as easy aggregation and difficult separation in water treatment.					
36436607	1	43	theme	Metal-organic	110:122	arg1	MOFs					136:139	MOFs	136:139	MOFs	136:139	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	1	43	theme	Metal-organic	110:122	arg1	frameworks					124:133	Metal-organic frameworks	110:133	Metal-organic frameworks (MOFs)	110:140	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	6	44	theme	removal	708:714	arg1	potential					716:724	The removal potential	704:724	The removal potential of toxic Cr(VI)	704:740	The removal potential of toxic Cr(VI) was tested by adsorption experiments.					
36436607	7	45	theme	adsorbent	849:857	arg1	layer					843:847	a single molecular layer	824:847	a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2	824:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	7	45	theme	adsorbent	849:857	arg1	FMCS-1					814:819	FMCS-1	814:819	FMCS-1	814:819	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	6	46	theme	toxic	729:733	arg1	Cr					735:736	toxic Cr	729:736	toxic Cr(VI)	729:740	The removal potential of toxic Cr(VI) was tested by adsorption experiments.					
36436607	11	47	dep	removal	1343:1349	arg1	VI					1339:1340	VI	1339:1340	VI	1339:1340	This work expands the application of MOFs in water treatment and also provides an effective adsorbent for Cr(VI) removal.					
36436607	8	48	theme	adsorption	924:933	arg1	kinetics					935:942	The adsorption kinetics	920:942	The adsorption kinetics	920:942	The adsorption kinetics showed that the adsorption of Cr(VI) by FMCS-1 was chemical adsorption.					
36436607	1	49	theme	huge	176:179	arg1	area					198:201	their huge specific surface area	170:201	their huge specific surface area	170:201	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	2	50	theme	easy	268:271	arg1	aggregation					273:283	easy aggregation	268:283	easy aggregation	268:283	However, there are problems such as easy aggregation and difficult separation in water treatment.					
36436607	7	51	theme	molecular	833:841	arg1	layer					843:847	a single molecular layer	824:847	a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2	824:917	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	7	51	theme	molecular	833:841	arg1	FMCS-1					814:819	FMCS-1	814:819	FMCS-1	814:819	The isotherm model indicated that FMCS-1 is a single molecular layer adsorbent with a maximum adsorption capacity of 109.46 mg/g at pH = 2.					
36436607	1	52	theme	specific	181:188	arg1	area					198:201	their huge specific surface area	170:201	their huge specific surface area	170:201	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	6	53	theme	adsorption	756:765	arg1	experiments					767:777	adsorption experiments	756:777	adsorption experiments	756:777	The removal potential of toxic Cr(VI) was tested by adsorption experiments.					
36436607	1	54	theme	surface	190:196	arg1	area					198:201	their huge specific surface area	170:201	their huge specific surface area	170:201	Metal-organic frameworks (MOFs) are gradually used since of their huge specific surface area and superior pore structure.					
36436607	4	55	theme	structural	443:452	arg1	characterization					454:469	structural characterization	443:469	structural characterization	443:469	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36436607	9	56	theme	acid	1086:1089	arg1	solutions					1091:1099	acid solutions	1086:1099	acid solutions	1086:1099	The acid resistance test demonstrated that FMCS-1 can exist stably in acid solutions.					
36436607	2	57	theme	water	313:317	arg1	treatment					319:327	water treatment	313:327	water treatment	313:327	However, there are problems such as easy aggregation and difficult separation in water treatment.					
36436607	4	58	dep	characterization	454:469	arg1	The					439:441	The	439:441	The	439:441	The structural characterization and performance analysis of the materials showed that the introduction of chitosan effectively prevents the stacking of MOFs.					
36579828	6	0	theme	3D	947:948	arg1	bioprinting					950:960	extrusion-based 3D bioprinting	931:960	extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations	931:1027	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	1	1	theme	donor	243:247	arg1	cornea					249:254	donor cornea	243:254	donor cornea	243:254	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	7	2	theme	corneal	1148:1154	arg1	structures					1163:1172	bioprinting corneal stroma structures	1136:1172	bioprinting corneal stroma structures	1136:1172	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	6	3	theme	property	1002:1009	arg1	characterizations					1011:1027	self-healing property characterizations	989:1027	self-healing property characterizations	989:1027	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	10	4	theme	shear	1630:1634	arg1	property					1645:1652	excellent shear thinning property	1620:1652	excellent shear thinning property	1620:1652	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	11	5	theme	excellentex	1865:1875	arg1	vivointegration					1877:1891	excellentex vivointegration	1865:1891	excellentex vivointegration to host tissue	1865:1906	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	5	6	theme	containing	719:728	arg1	bioink					730:735	a hyaluronic acid-based dopamine containing bioink	686:735	a hyaluronic acid-based dopamine containing bioink	686:735	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	2	7	theme	3D	281:282	arg1	bioprinting					284:294	3D bioprinting	281:294	3D bioprinting	281:294	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	1	8	theme	severe	198:203	arg1	diseases					212:219	severe cornea diseases	198:219	severe cornea diseases	198:219	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	10	9	theme	shape	1680:1684	arg1	fidelity					1686:1693	shape fidelity	1680:1693	shape fidelity	1680:1693	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	4	10	theme	cells	660:664	arg1	functionality					631:643	biological functionality	620:643	biological functionality of the printed cells	620:664	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	7	11	theme	stromal	1102:1108	arg1	keratocytes					1110:1120	hASC-derived corneal stromal keratocytes	1081:1120	hASC-derived corneal stromal keratocytes	1081:1120	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	4	12	contain	possess	597:603	arg1	stabilization					544:556	the stabilization	540:556	the stabilization	540:556	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	4	12	contain	possess	597:603	arg2	limitations					605:615	limitations	605:615	limitations on biological functionality of the printed cells	605:664	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	1	13	theme	diseases	212:219	arg1	treatment					185:193	the treatment	181:193	the treatment of severe cornea diseases	181:219	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	6	14	theme	shape	970:974	arg1	fidelity					976:983	the shape fidelity	966:983	the shape fidelity	966:983	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	7	15	theme	hASC-derived	1081:1092	arg1	keratocytes					1110:1120	hASC-derived corneal stromal keratocytes	1081:1120	hASC-derived corneal stromal keratocytes	1081:1120	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	16	theme	adipose	1050:1056	arg1	hASCs					1070:1074	hASCs	1070:1074	hASCs	1070:1074	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	16	theme	adipose	1050:1056	arg1	cells					1063:1067	human adipose stem cells	1044:1067	human adipose stem cells (hASCs)	1044:1075	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	5	17	theme	acid-based	699:708	arg1	bioink					730:735	a hyaluronic acid-based dopamine containing bioink	686:735	a hyaluronic acid-based dopamine containing bioink	686:735	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	9	18	theme	pluripotent	1462:1472	arg1	cell					1479:1482	human pluripotent stem cell	1456:1482	human pluripotent stem cell	1456:1482	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	8	19	theme	bioprinted	1345:1354	arg1	structures					1364:1373	3D bioprinted stromal structures	1342:1373	3D bioprinted stromal structures	1342:1373	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	0	20	with	model	107:111	arg1	innervation					118:128	innervation	118:128	innervation	118:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	11	21	theme	tissue	1799:1804	arg1	formation					1806:1814	good tissue formation	1794:1814	good tissue formation	1794:1814	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	1	22	theme	cornea	249:254	arg1	bottleneck					269:278	a serious bottleneck	259:278	a serious bottleneck	259:278	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	1	22	theme	cornea	249:254	arg1	scarcity					231:238	scarcity	231:238	scarcity of donor cornea	231:254	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	4	23	theme	ionic	502:506	arg1	crosslinking					508:519	ionic crosslinking	502:519	ionic crosslinking	502:519	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	3	24	with	compositions	419:430	arg1	cytocompatibility					460:476	cytocompatibility	460:476	cytocompatibility	460:476	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	3	24	with	compositions	419:430	arg1	printability					443:454	ideal printability	437:454	ideal printability	437:454	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	0	25	theme	human	67:71	arg1	cell					78:81	human stem cell	67:81	human stem cell derived corneal stromal model with innervation	67:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	12	26	theme	great	2008:2012	arg1	potential					2014:2022	great potential	2008:2022	great potential for cornea TE applications	2008:2049	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	9	27	theme	structures	1567:1576	arg1	periphery					1542:1550	the periphery	1538:1550	the periphery of the corneal structures to analyze innervation	1538:1599	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	11	28	theme	bioprinted	1823:1832	arg1	structures					1841:1850	3D bioprinted cornea structures	1820:1850	3D bioprinted cornea structures	1820:1850	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	0	29	theme	cell	78:81	arg1	bioink					38:43	next generation bioink	22:43	next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	22:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	8	30	theme	vivoporcine	1397:1407	arg1	cornea					1409:1414	intoex vivoporcine cornea	1390:1414	intoex vivoporcine cornea	1390:1414	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	3	31	theme	bioink	412:417	arg1	compositions					419:430	design bioink compositions	405:430	design bioink compositions with ideal printability and cytocompatibility	405:476	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	0	32	theme	corneal	91:97	arg1	model					107:111	corneal stromal model	91:111	corneal stromal model with innervation	91:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	12	33	theme	cornea	1976:1981	arg1	equivalents					1991:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	0	34	theme	Hyaluronic	0:9	arg1	acid					11:14	Hyaluronic acid	0:14	Hyaluronic acid	0:14	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	8	35	theme	tissue	1427:1432	arg1	integration					1434:1444	tissue integration	1427:1444	tissue integration	1427:1444	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	12	36	theme	bioink	1953:1958	arg1	equivalents					1991:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	3	37	theme	challenges	388:397	arg1	challenges					388:397	the key technological challenges	366:397	the key technological challenges	366:397	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	3	37	theme	challenges	388:397	arg1	One					359:361	One	359:361	One	359:361	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	4	38	theme	bioprinted	564:573	arg1	structures					575:584	3D bioprinted structures	561:584	3D bioprinted structures	561:584	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	0	39	theme	generation	27:36	arg1	bioink					38:43	next generation bioink	22:43	next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	22:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	5	40	theme	equivalents	810:820	arg1	bioprinting					787:797	the 3D bioprinting	780:797	the 3D bioprinting of corneal equivalents	780:820	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	6	41	theme	mechanical	874:883	arg1	stability					885:893	mechanical stability	874:893	mechanical stability	874:893	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	3	42	theme	key	370:372	arg1	challenges					388:397	the key technological challenges	366:397	the key technological challenges	366:397	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	5	43	theme	3D	784:785	arg1	bioprinting					787:797	the 3D bioprinting	780:797	the 3D bioprinting of corneal equivalents	780:820	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	9	44	dep	derived	1484:1490	arg1	cell					1479:1482	human pluripotent stem cell	1456:1482	human pluripotent stem cell	1456:1482	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	2	45	theme	tissue	334:339	arg1	TE					354:355	TE	354:355	TE	354:355	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	2	45	theme	tissue	334:339	arg1	engineering					341:351	cornea tissue engineering	327:351	cornea tissue engineering (TE)	327:356	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	7	46	dep	proteins	1252:1259	arg1	actin					1309:1313	α-smooth muscle actin	1293:1313	α-smooth muscle actin	1293:1313	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	46	dep	proteins	1252:1259	arg1	connexin					1281:1288	connexin 43	1281:1291	connexin 43	1281:1291	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	46	dep	proteins	1252:1259	arg1	vimentin					1271:1278	vimentin	1271:1278	vimentin	1271:1278	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	46	dep	proteins	1252:1259	arg1	lumican					1262:1268	lumican	1262:1268	lumican	1262:1268	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	11	47	theme	good	1794:1797	arg1	formation					1806:1814	good tissue formation	1794:1814	good tissue formation	1794:1814	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	3	48	theme	ideal	437:441	arg1	printability					443:454	ideal printability	437:454	ideal printability	437:454	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	0	49	theme	3D	49:50	arg1	bioprinting					52:62	3D bioprinting	49:62	3D bioprinting	49:62	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	7	50	theme	α-smooth	1293:1300	arg1	actin					1309:1313	α-smooth muscle actin	1293:1313	α-smooth muscle actin	1293:1313	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	50	theme	α-smooth	1293:1300	arg1	lumican					1262:1268	lumican	1262:1268	lumican	1262:1268	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	4	51	theme	biological	620:629	arg1	functionality					631:643	biological functionality	620:643	biological functionality of the printed cells	620:664	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	9	52	theme	human	1456:1460	arg1	cell					1479:1482	human pluripotent stem cell	1456:1482	human pluripotent stem cell	1456:1482	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	6	53	theme	extrusion-based	931:945	arg1	bioprinting					950:960	extrusion-based 3D bioprinting	931:960	extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations	931:1027	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	10	54	theme	excellent	1620:1628	arg1	property					1645:1652	excellent shear thinning property	1620:1652	excellent shear thinning property	1620:1652	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	7	55	theme	stroma	1156:1161	arg1	structures					1163:1172	bioprinting corneal stroma structures	1136:1172	bioprinting corneal stroma structures	1136:1172	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	6	56	theme	shear	834:838	arg1	thinning					840:847	the shear thinning property, viscosity, and mechanical stability	830:893	thinning	840:847	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	9	57	theme	stem	1474:1477	arg1	cell					1479:1482	human pluripotent stem cell	1456:1482	human pluripotent stem cell	1456:1482	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	7	58	used	used	1127:1130	arg2	keratocytes					1110:1120	hASC-derived corneal stromal keratocytes	1081:1120	hASC-derived corneal stromal keratocytes	1081:1120	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	58	used	used	1127:1130	arg2	cells					1063:1067	human adipose stem cells	1044:1067	human adipose stem cells (hASCs)	1044:1075	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	58	used	used	1127:1130	arg2	hASCs					1070:1074	hASCs	1070:1074	hASCs	1070:1074	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	59	theme	bioprinting	1136:1146	arg1	structures					1163:1172	bioprinting corneal stroma structures	1136:1172	bioprinting corneal stroma structures	1136:1172	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	9	60	theme	derived	1484:1490	arg1	hPSC-neurons					1501:1512	hPSC-neurons	1501:1512	hPSC-neurons	1501:1512	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	9	60	theme	derived	1484:1490	arg1	neurons					1492:1498	human pluripotent stem cell derived neurons	1456:1498	human pluripotent stem cell derived neurons (hPSC-neurons)	1456:1513	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	6	61	theme	bioink	902:907	arg1	viscosity					859:867	viscosity	859:867	viscosity	859:867	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	6	61	theme	bioink	902:907	arg1	stability					885:893	mechanical stability	874:893	mechanical stability	874:893	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	6	61	theme	bioink	902:907	arg1	thinning					840:847	the shear thinning property, viscosity, and mechanical stability	830:893	thinning	840:847	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	4	62	from	limitations	605:615	arg1	functionality					631:643	biological functionality	620:643	biological functionality of the printed cells	620:664	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	4	63	used	used	531:534	arg2	crosslinking					508:519	ionic crosslinking	502:519	ionic crosslinking	502:519	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	4	63	used	used	531:534	arg2	Photo-crosslinking					479:496	Photo-crosslinking	479:496	Photo-crosslinking	479:496	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	2	64	theme	tremendous	302:311	arg1	potential					313:321	tremendous potential	302:321	tremendous potential for cornea tissue engineering (TE)	302:356	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	10	65	theme	thinning	1636:1643	arg1	property					1645:1652	excellent shear thinning property	1620:1652	excellent shear thinning property	1620:1652	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	11	66	theme	host	1896:1899	arg1	tissue					1901:1906	host tissue	1896:1906	host tissue	1896:1906	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	5	67	theme	dopamine	710:717	arg1	bioink					730:735	a hyaluronic acid-based dopamine containing bioink	686:735	a hyaluronic acid-based dopamine containing bioink	686:735	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	6	68	theme	self-healing	989:1000	arg1	characterizations					1011:1027	self-healing property characterizations	989:1027	self-healing property characterizations	989:1027	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	6	69	dep	thinning	840:847	arg1	property					849:856	property	849:856	property	849:856	First, the shear thinning property, viscosity, and mechanical stability of the bioink were optimized before extrusion-based 3D bioprinting for the shape fidelity and self-healing property characterizations.					
36579828	7	70	theme	corneal	1094:1100	arg1	keratocytes					1110:1120	hASC-derived corneal stromal keratocytes	1081:1120	hASC-derived corneal stromal keratocytes	1081:1120	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	1	71	theme	cornea	205:210	arg1	diseases					212:219	severe cornea diseases	198:219	severe cornea diseases	198:219	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	12	72	theme	TE	2035:2036	arg1	applications					2038:2049	cornea TE applications	2028:2049	cornea TE applications	2028:2049	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	4	73	theme	printed	652:658	arg1	cells					660:664	the printed cells	648:664	the printed cells	648:664	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	7	74	theme	proteins	1252:1259	arg1	microstructure					1215:1228	microstructure	1215:1228	microstructure	1215:1228	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	74	theme	proteins	1252:1259	arg1	proliferation					1200:1212	proliferation	1200:1212	proliferation	1200:1212	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	74	theme	proteins	1252:1259	arg1	viability					1189:1197	their cell viability	1178:1197	their cell viability	1178:1197	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	74	theme	proteins	1252:1259	arg1	expression					1234:1243	expression	1234:1243	expression	1234:1243	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	5	75	theme	hyaluronic	688:697	arg1	bioink					730:735	a hyaluronic acid-based dopamine containing bioink	686:735	a hyaluronic acid-based dopamine containing bioink	686:735	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	7	76	theme	stem	1058:1061	arg1	hASCs					1070:1074	hASCs	1070:1074	hASCs	1070:1074	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	76	theme	stem	1058:1061	arg1	cells					1063:1067	human adipose stem cells	1044:1067	human adipose stem cells (hASCs)	1044:1075	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	11	77	theme	3D	1820:1821	arg1	structures					1841:1850	3D bioprinted cornea structures	1820:1850	3D bioprinted cornea structures	1820:1850	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	7	78	theme	human	1044:1048	arg1	hASCs					1070:1074	hASCs	1070:1074	hASCs	1070:1074	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	78	theme	human	1044:1048	arg1	cells					1063:1067	human adipose stem cells	1044:1067	human adipose stem cells (hASCs)	1044:1075	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	1	79	theme	Corneal	131:137	arg1	transplantation					139:153	Corneal transplantation	131:153	Corneal transplantation	131:153	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	8	80	theme	3D	1342:1343	arg1	structures					1364:1373	3D bioprinted stromal structures	1342:1373	3D bioprinted stromal structures	1342:1373	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	5	81	theme	crosslinking	753:764	arg1	chemistry					766:774	hydrazone crosslinking chemistry	743:774	hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents	743:820	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	0	82	theme	stem	73:76	arg1	cell					78:81	human stem cell	67:81	human stem cell derived corneal stromal model with innervation	67:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	9	83	theme	corneal	1559:1565	arg1	structures					1567:1576	the corneal structures	1555:1576	the corneal structures	1555:1576	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	8	84	theme	stromal	1356:1362	arg1	structures					1364:1373	3D bioprinted stromal structures	1342:1373	3D bioprinted stromal structures	1342:1373	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	5	85	theme	hydrazone	743:751	arg1	chemistry					766:774	hydrazone crosslinking chemistry	743:774	hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents	743:820	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	12	86	theme	cornea	2028:2033	arg1	applications					2038:2049	cornea TE applications	2028:2049	cornea TE applications	2028:2049	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	11	87	from	Cells	1752:1756	arg1	structures					1773:1782	the printed structures	1761:1782	the printed structures	1761:1782	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	11	88	theme	cornea	1834:1839	arg1	structures					1841:1850	3D bioprinted cornea structures	1820:1850	3D bioprinted cornea structures	1820:1850	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	0	89	theme	stromal	99:105	arg1	model					107:111	corneal stromal model	91:111	corneal stromal model with innervation	91:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	12	90	theme	stromal	1983:1989	arg1	equivalents					1991:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents	1939:2001	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	8	91	theme	intoex	1390:1395	arg1	cornea					1409:1414	intoex vivoporcine cornea	1390:1414	intoex vivoporcine cornea	1390:1414	Moreover, 3D bioprinted stromal structures were implanted intoex vivoporcine cornea to explore tissue integration.					
36579828	9	92	link	derived	1484:1490	arg1	hPSC-neurons					1501:1512	hPSC-neurons	1501:1512	hPSC-neurons	1501:1512	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	9	92	link	derived	1484:1490	arg1	neurons					1492:1498	human pluripotent stem cell derived neurons	1456:1498	human pluripotent stem cell derived neurons (hPSC-neurons)	1456:1513	Finally, human pluripotent stem cell derived neurons (hPSC-neurons), were 3D bioprinted to the periphery of the corneal structures to analyze innervation.					
36579828	4	93	theme	3D	561:562	arg1	structures					575:584	3D bioprinted structures	561:584	3D bioprinted structures	561:584	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	3	94	theme	design	405:410	arg1	compositions					419:430	design bioink compositions	405:430	design bioink compositions with ideal printability and cytocompatibility	405:476	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	0	95	theme	next	22:25	arg1	bioink					38:43	next generation bioink	22:43	next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	22:128	Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation.					
36579828	1	96	theme	serious	261:267	arg1	bottleneck					269:278	a serious bottleneck	259:278	a serious bottleneck	259:278	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	1	96	theme	serious	261:267	arg1	scarcity					231:238	scarcity	231:238	scarcity of donor cornea	231:254	Corneal transplantation remains gold standard for the treatment of severe cornea diseases, however, scarcity of donor cornea is a serious bottleneck.					
36579828	4	97	theme	structures	575:584	arg1	stabilization					544:556	the stabilization	540:556	the stabilization	540:556	Photo-crosslinking and ionic crosslinking are often used for the stabilization of 3D bioprinted structures, which can possess limitations on biological functionality of the printed cells.					
36579828	10	98	theme	high	1728:1731	arg1	cytocompatibility					1733:1749	high cytocompatibility	1728:1749	high cytocompatibility	1728:1749	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	5	99	theme	corneal	802:808	arg1	equivalents					810:820	corneal equivalents	802:820	corneal equivalents	802:820	Here, we developed a hyaluronic acid-based dopamine containing bioink using hydrazone crosslinking chemistry for the 3D bioprinting of corneal equivalents.					
36579828	12	100	theme	printed	1968:1974	arg1	cornea					1976:1981	the printed cornea	1964:1981	the printed cornea	1964:1981	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	10	101	theme	self-healing	1699:1710	arg1	properties					1712:1721	self-healing properties	1699:1721	self-healing properties	1699:1721	The bioink showed excellent shear thinning property, viscosity, printability, shape fidelity and self-healing properties with high cytocompatibility.					
36579828	7	102	theme	key	1248:1250	arg1	proteins					1252:1259	key proteins	1248:1259	key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin)	1248:1314	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	103	theme	cell	1184:1187	arg1	viability					1189:1197	their cell viability	1178:1197	their cell viability	1178:1197	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	3	104	theme	technological	374:386	arg1	challenges					388:397	the key technological challenges	366:397	the key technological challenges	366:397	One of the key technological challenges is to design bioink compositions with ideal printability and cytocompatibility.					
36579828	2	105	theme	cornea	327:332	arg1	TE					354:355	TE	354:355	TE	354:355	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	2	105	theme	cornea	327:332	arg1	engineering					341:351	cornea tissue engineering	327:351	cornea tissue engineering (TE)	327:356	3D bioprinting holds tremendous potential for cornea tissue engineering (TE).					
36579828	12	106	theme	developed	1943:1951	arg1	bioink					1953:1958	The developed bioink	1939:1958	The developed bioink	1939:1958	The developed bioink and the printed cornea stromal equivalents hold great potential for cornea TE applications.					
36579828	7	107	theme	muscle	1302:1307	arg1	actin					1309:1313	α-smooth muscle actin	1293:1313	α-smooth muscle actin	1293:1313	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	7	107	theme	muscle	1302:1307	arg1	lumican					1262:1268	lumican	1262:1268	lumican	1262:1268	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	11	108	theme	printed	1765:1771	arg1	structures					1773:1782	the printed structures	1761:1782	the printed structures	1761:1782	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36579828	7	109	link	hASC-derived	1081:1092	arg1	keratocytes					1110:1120	hASC-derived corneal stromal keratocytes	1081:1120	hASC-derived corneal stromal keratocytes	1081:1120	Subsequently, human adipose stem cells (hASCs) and hASC-derived corneal stromal keratocytes were used for bioprinting corneal stroma structures and their cell viability, proliferation, microstructure and expression of key proteins (lumican, vimentin, connexin 43,α-smooth muscle actin) were evaluated.					
36579828	11	110	theme	asin	1916:1919	arg1	vitroinnervation					1921:1936	well asin vitroinnervation	1911:1936	well asin vitroinnervation	1911:1936	Cells in the printed structures displayed good tissue formation and 3D bioprinted cornea structures demonstrated excellentex vivointegration to host tissue as well asin vitroinnervation.					
36084104	0	0	theme	new	77:79	arg1	aldehyde					81:88	new aldehyde	77:88	new aldehyde to form a schiff base	77:110	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	1	1	theme	2,2'-	128:132	arg1	dibenzaldehyde					160:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	1	2	theme	2-hydroxy	233:241	arg1	1,3-dichloropropanean					243:263	2-hydroxy 1,3-dichloropropanean	233:263	2-hydroxy 1,3-dichloropropanean	233:263	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	7	3	theme	high	1021:1024	arg1	value					1026:1030	a high value 5 times	1019:1038	a high value 5 times	1019:1038	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	6	4	theme	second-order	799:810	arg1	reaction					812:819	a second-order reaction	797:819	a second-order reaction	797:819	The adsorption process followed a second-order reaction and Langmuir model with qe 25 mg/g, 121 mg/g, and 26.31 mg/g for Cu(II), Zn(II), and Cr(III) respectively.					
36084104	1	5	theme	[propane-1,3-diylbis	133:152	arg1	dibenzaldehyde					160:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	4	6	theme	Cr	673:674	arg1	ions					699:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	7	theme	initial	571:577	arg1	concentration					579:591	initial concentration	571:591	initial concentration of metal ions	571:605	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	3	8	theme	new	499:501	arg1	aldehyde					503:510	a new aldehyde	497:510	a new aldehyde	497:510	The extracted chitosan was made to react with a new aldehyde to form a Schiff base by a suitable method.					
36084104	4	9	from	effects	560:566	arg1	adsorption					651:660	the adsorption	647:660	the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	647:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	10	theme	Cu	665:666	arg1	ions					699:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	11	theme	weight	629:634	arg1	effects					560:566	The effects	556:566	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	556:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	7	12	theme	adsorption/desorption	982:1002	arg1	tests					1004:1008	the adsorption/desorption tests	978:1008	the adsorption/desorption tests	978:1008	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	6	13	theme	adsorption	769:778	arg1	process					780:786	The adsorption process	765:786	The adsorption process	765:786	The adsorption process followed a second-order reaction and Langmuir model with qe 25 mg/g, 121 mg/g, and 26.31 mg/g for Cu(II), Zn(II), and Cr(III) respectively.					
36084104	3	14	theme	Schiff	522:527	arg1	base					529:532	a Schiff base	520:532	a Schiff base	520:532	The extracted chitosan was made to react with a new aldehyde to form a Schiff base by a suitable method.					
36084104	1	15	theme	oxy	154:156	arg1	dibenzaldehyde					160:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	0	16	theme	Rapid	0:4	arg1	adsorption					6:15	Rapid adsorption	0:15	Rapid adsorption of some heavy metals using extracted chitosan	0:61	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	1	17	theme	alcoholic	271:279	arg1	medium					281:286	an alcoholic medium	268:286	an alcoholic medium	268:286	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	5	18	theme	adsorption	722:731	arg1	experiment					739:748	An adsorption batch experiment	719:748	An adsorption batch experiment	719:748	An adsorption batch experiment was conducted.					
36084104	2	19	theme	resonance	419:427	arg1	studies					442:448	nuclear magnetic resonance spectroscopy studies	402:448	nuclear magnetic resonance spectroscopy studies	402:448	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	2	20	theme	spectroscopy	429:440	arg1	studies					442:448	nuclear magnetic resonance spectroscopy studies	402:448	nuclear magnetic resonance spectroscopy studies	402:448	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	0	21	theme	schiff	100:105	arg1	base					107:110	a schiff base	98:110	a schiff base	98:110	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	3	22	theme	suitable	539:546	arg1	method					548:553	a suitable method	537:553	a suitable method	537:553	The extracted chitosan was made to react with a new aldehyde to form a Schiff base by a suitable method.					
36084104	2	23	theme	magnetic	410:417	arg1	resonance					419:427	nuclear magnetic resonance	402:427	nuclear magnetic resonance spectroscopy studies	402:448	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	0	24	theme	metals	31:36	arg1	adsorption					6:15	Rapid adsorption	0:15	Rapid adsorption of some heavy metals using extracted chitosan	0:61	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	2	25	dep	compositions	293:304	arg1	The					289:291	The	289:291	The	289:291	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	7	26	dep	value	1026:1030	arg1	times					1034:1038	5 times	1032:1038	a high value 5 times	1019:1038	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	3	27	theme	extracted	455:463	arg1	chitosan					465:472	The extracted chitosan	451:472	The extracted chitosan	451:472	The extracted chitosan was made to react with a new aldehyde to form a Schiff base by a suitable method.					
36084104	4	28	theme	ions	699:702	arg1	adsorption					651:660	the adsorption	647:660	the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	647:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	2	29	theme	nuclear	402:408	arg1	resonance					419:427	nuclear magnetic resonance	402:427	nuclear magnetic resonance spectroscopy studies	402:448	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	0	30	theme	heavy	25:29	arg1	metals					31:36	some heavy metals	20:36	some heavy metals using extracted chitosan	20:61	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	4	31	theme	metal	693:697	arg1	ions					699:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	32	theme	time	617:620	arg1	effects					560:566	The effects	556:566	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	556:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	0	33	theme	extracted	44:52	arg1	chitosan					54:61	extracted chitosan	44:61	extracted chitosan	44:61	Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base.					
36084104	2	34	theme	compound	341:348	arg1	properties					310:319	properties	310:319	properties	310:319	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	2	34	theme	compound	341:348	arg1	compositions					293:304	compositions	293:304	compositions	293:304	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	4	35	theme	concentration	579:591	arg1	effects					560:566	The effects	556:566	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	556:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	2	36	theme	aldehyde	332:339	arg1	compound					341:348	the new aldehyde compound	324:348	the new aldehyde compound	324:348	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	6	37	theme	Langmuir	825:832	arg1	model					834:838	Langmuir model	825:838	Langmuir model	825:838	The adsorption process followed a second-order reaction and Langmuir model with qe 25 mg/g, 121 mg/g, and 26.31 mg/g for Cu(II), Zn(II), and Cr(III) respectively.					
36084104	1	38	theme	new	115:117	arg1	dibenzaldehyde					160:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	7	39	theme	free	938:941	arg1	energy					943:948	The Gibbs free energy	928:948	The Gibbs free energy	928:948	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	2	40	theme	new	328:330	arg1	compound					341:348	the new aldehyde compound	324:348	the new aldehyde compound	324:348	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	1	41	theme	refluxing	196:204	arg1	acetophenone					216:227	refluxing 2-hydroxy acetophenone	196:227	refluxing 2-hydroxy acetophenone	196:227	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	4	42	theme	Zn	686:687	arg1	ions					699:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	Cu(II), Cr(III), and Zn(II) metal ions	665:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	43	theme	pH	641:642	arg1	effects					560:566	The effects	556:566	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions	556:702	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	1	44	theme	2-hydroxy	206:214	arg1	acetophenone					216:227	refluxing 2-hydroxy acetophenone	196:227	refluxing 2-hydroxy acetophenone	196:227	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	5	45	theme	batch	733:737	arg1	experiment					739:748	An adsorption batch experiment	719:748	An adsorption batch experiment	719:748	An adsorption batch experiment was conducted.					
36084104	4	46	theme	exposure	608:615	arg1	time					617:620	exposure time	608:620	exposure time	608:620	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	2	47	theme	elemental	372:380	arg1	analysis					382:389	elemental analysis	372:389	elemental analysis	372:389	The compositions and properties of the new aldehyde compound were characterized by elemental analysis, FTIR, and nuclear magnetic resonance spectroscopy studies.					
36084104	4	48	theme	imine	623:627	arg1	weight					629:634	imine weight	623:634	imine weight	623:634	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	49	theme	ions	602:605	arg1	time					617:620	exposure time	608:620	exposure time	608:620	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	49	theme	ions	602:605	arg1	weight					629:634	imine weight	623:634	imine weight	623:634	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	49	theme	ions	602:605	arg1	pH					641:642	pH	641:642	pH	641:642	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	4	49	theme	ions	602:605	arg1	concentration					579:591	initial concentration	571:591	initial concentration of metal ions	571:605	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
36084104	7	50	theme	Gibbs	932:936	arg1	energy					943:948	The Gibbs free energy	928:948	The Gibbs free energy	928:948	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	7	51	theme	negative	959:966	arg1	value					968:972	a negative value	957:972	a negative value	957:972	The Gibbs free energy showed a negative value and the adsorption/desorption tests provided a high value 5 times.					
36084104	1	52	theme	aldehyde	119:126	arg1	dibenzaldehyde					160:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde	113:173	A new aldehyde 2,2'-[propane-1,3-diylbis(oxy)] dibenzaldehyde was synthesized from refluxing 2-hydroxy acetophenone and 2-hydroxy 1,3-dichloropropanean in an alcoholic medium.					
36084104	4	53	theme	metal	596:600	arg1	ions					602:605	metal ions	596:605	metal ions	596:605	The effects of initial concentration of metal ions, exposure time, imine weight, and pH on the adsorption of Cu(II), Cr(III), and Zn(II) metal ions were examined.					
35367272	9	0	theme	cell	1457:1460	arg1	adhesion					1462:1469	cell adhesion	1457:1469	cell adhesion	1457:1469	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	1	1	dep	chitosan	298:305	arg1	nanocrystals					321:332	nanocrystals	321:332	nanocrystals	321:332	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	0	2	dep	scaffold	137:144	arg1	Effect					0:5	Effect	0:5	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals	0:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	2	3	from	use	509:511	arg1	engineering					528:538	bone tissue engineering	516:538	bone tissue engineering	516:538	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	1	4	theme	scaffolds	279:287	arg1	characteristics					260:274	the main characteristics	251:274	the main characteristics of scaffolds based on chitosan and cellulose nanocrystals	251:332	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	8	5	theme	biomineralization	1318:1334	arg1	ability					1336:1342	good biomineralization ability	1313:1342	good biomineralization ability	1313:1342	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	0	6	from	Effect	0:5	arg1	characteristics					86:100	the characteristics	82:100	the characteristics of chitosan/cellulose nanocrystals	82:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	3	7	theme	prepared	581:588	arg1	scaffolds					590:598	prepared scaffolds	581:598	prepared scaffolds	581:598	The structural and chemical features of prepared scaffolds were studied by the FTIR technique.					
35367272	1	8	theme	calcium	180:186	arg1	cations					188:194	glutaraldehyde and calcium cations	161:194	glutaraldehyde and calcium cations as covalent and ionic crosslinkers	161:229	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	5	9	theme	scaffolds	806:814	arg1	stability					793:801	the thermal stability	781:801	the thermal stability of scaffolds based on chitosan/cellulose nanocrystals	781:855	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	6	10	theme	compressive	1032:1042	arg1	strength					1044:1051	the highest compressive strength	1020:1051	the highest compressive strength	1020:1051	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	10	11	theme	cells	1516:1520	arg1	lower					1581:1585	lower	1581:1585	lower	1581:1585	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	10	11	theme	cells	1516:1520	arg1	viability					1485:1493	the viability	1481:1493	the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds	1481:1575	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	9	12	theme	viability	1354:1362	arg1	results					1384:1390	The cell viability and cell attachment results	1345:1390	The cell viability and cell attachment results	1345:1390	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	3	13	theme	structural	545:554	arg1	features					569:576	The structural and chemical features	541:576	The structural and chemical features of prepared scaffolds	541:598	The structural and chemical features of prepared scaffolds were studied by the FTIR technique.					
35367272	0	14	theme	nanocrystals	124:135	arg1	characteristics					86:100	the characteristics	82:100	the characteristics of chitosan/cellulose nanocrystals	82:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	6	15	theme	highest	1024:1030	arg1	strength					1044:1051	the highest compressive strength	1020:1051	the highest compressive strength	1020:1051	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	4	16	theme	three-dimensional	695:711	arg1	samples					676:682	all scaffold samples	663:682	all scaffold samples	663:682	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	4	16	theme	three-dimensional	695:711	arg1	networks					713:720	porous three-dimensional networks	688:720	porous three-dimensional networks in which the pores are connected	688:753	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	6	17	link	uncrosslinked	1061:1073	arg1	scaffold					1075:1082	the uncrosslinked scaffold	1057:1082	the uncrosslinked scaffold	1057:1082	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	1	18	theme	cations	188:194	arg1	effect					151:156	The effect	147:156	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers	147:229	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	0	19	theme	chitosan/cellulose	105:122	arg1	nanocrystals					124:135	chitosan/cellulose nanocrystals	105:135	chitosan/cellulose nanocrystals	105:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	9	20	theme	attachment	1373:1382	arg1	results					1384:1390	The cell viability and cell attachment results	1345:1390	The cell viability and cell attachment results	1345:1390	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	9	21	theme	cell	1368:1371	arg1	attachment					1373:1382	cell attachment	1368:1382	cell attachment	1368:1382	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	3	22	theme	scaffolds	590:598	arg1	features					569:576	The structural and chemical features	541:576	The structural and chemical features of prepared scaffolds	541:598	The structural and chemical features of prepared scaffolds were studied by the FTIR technique.					
35367272	8	23	theme	fabricated	1287:1296	arg1	scaffolds					1298:1306	fabricated scaffolds	1287:1306	fabricated scaffolds	1287:1306	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	1	24	theme	covalent	199:206	arg1	crosslinkers					218:229	covalent and ionic crosslinkers	199:229	covalent and ionic crosslinkers	199:229	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	5	25	theme	different	901:909	arg1	methods					924:930	different crosslinking methods	901:930	different crosslinking methods	901:930	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	8	26	contain	have	1308:1311	arg1	scaffolds					1298:1306	fabricated scaffolds	1287:1306	fabricated scaffolds	1287:1306	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	8	26	contain	have	1308:1311	arg2	ability					1336:1342	good biomineralization ability	1313:1342	good biomineralization ability	1313:1342	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	2	27	theme	crosslinking	427:438	arg1	methods					440:446	different crosslinking methods	417:446	different crosslinking methods	417:446	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	2	28	theme	potential	499:507	arg1	use					509:511	potential use	499:511	potential use in bone tissue engineering	499:538	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	10	29	theme	scaffolds	1567:1575	arg1	presence					1529:1536	the presence	1525:1536	the presence of glutaraldehyde-containing scaffolds	1525:1575	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	3	30	theme	FTIR	620:623	arg1	technique					625:633	the FTIR technique	616:633	the FTIR technique	616:633	The structural and chemical features of prepared scaffolds were studied by the FTIR technique.					
35367272	1	31	theme	ionic	212:216	arg1	crosslinkers					218:229	covalent and ionic crosslinkers	199:229	covalent and ionic crosslinkers	199:229	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	0	32	theme	glutaraldehyde	10:23	arg1	Effect					0:5	Effect	0:5	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals	0:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	4	33	theme	FESEM	636:640	arg1	images					642:647	FESEM images	636:647	FESEM images	636:647	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	7	34	theme	calcium	1225:1231	arg1	cations					1233:1239	calcium cations	1225:1239	calcium cations	1225:1239	The fastest degradation rate belonged to the scaffold crosslinked by calcium cations.					
35367272	2	35	theme	chitosan/cellulose	380:397	arg1	nanocrystals					399:410	chitosan/cellulose nanocrystals	380:410	chitosan/cellulose nanocrystals with different crosslinking methods	380:446	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	2	36	theme	freeze-drying	474:486	arg1	method					488:493	the freeze-drying method	470:493	the freeze-drying method for potential use in bone tissue engineering	470:538	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	0	37	theme	chloride	37:44	arg1	Effect					0:5	Effect	0:5	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals	0:135	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	6	38	theme	swelling	1103:1110	arg1	ratio					1112:1116	the highest swelling ratio	1091:1116	the highest swelling ratio	1091:1116	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	5	39	theme	thermal	785:791	arg1	stability					793:801	the thermal stability	781:801	the thermal stability of scaffolds based on chitosan/cellulose nanocrystals	781:855	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	0	40	theme	calcium	29:35	arg1	chloride					37:44	calcium chloride	29:44	calcium chloride	29:44	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	6	41	theme	highest	1095:1101	arg1	ratio					1112:1116	the highest swelling ratio	1091:1116	the highest swelling ratio	1091:1116	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	6	42	theme	other	1139:1143	arg1	scaffolds					1145:1153	the other scaffolds	1135:1153	the other scaffolds	1135:1153	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	4	43	theme	porous	688:693	arg1	samples					676:682	all scaffold samples	663:682	all scaffold samples	663:682	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	4	43	theme	porous	688:693	arg1	networks					713:720	porous three-dimensional networks	688:720	porous three-dimensional networks in which the pores are connected	688:753	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	7	44	theme	fastest	1160:1166	arg1	rate					1180:1183	The fastest degradation rate	1156:1183	The fastest degradation rate	1156:1183	The fastest degradation rate belonged to the scaffold crosslinked by calcium cations.					
35367272	5	45	theme	crosslinking	911:922	arg1	methods					924:930	different crosslinking methods	901:930	different crosslinking methods	901:930	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	2	46	theme	tissue	521:526	arg1	engineering					528:538	bone tissue engineering	516:538	bone tissue engineering	516:538	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	6	47	dep	crosslinked	978:988	arg1	nanocrystals					956:967	The chitosan/cellulose nanocrystals	933:967	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde	933:1006	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	6	47	dep	crosslinked	978:988	arg1	scaffold					969:976	scaffold	969:976	scaffold	969:976	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	8	48	theme	EDX	1259:1261	arg1	analysis					1263:1270	EDX analysis	1259:1270	EDX analysis	1259:1270	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	0	49	theme	crosslinking	59:70	arg1	agents					72:77	different crosslinking agents	49:77	different crosslinking agents	49:77	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	7	50	theme	degradation	1168:1178	arg1	rate					1180:1183	The fastest degradation rate	1156:1183	The fastest degradation rate	1156:1183	The fastest degradation rate belonged to the scaffold crosslinked by calcium cations.					
35367272	2	51	theme	bone	516:519	arg1	engineering					528:538	bone tissue engineering	516:538	bone tissue engineering	516:538	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	5	52	theme	TGA	756:758	arg1	analysis					760:767	TGA analysis	756:767	TGA analysis	756:767	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	2	53	with	nanocrystals	399:410	arg1	methods					440:446	different crosslinking methods	417:446	different crosslinking methods	417:446	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	9	54	theme	cell	1434:1437	arg1	proliferation					1439:1451	cell proliferation	1434:1451	cell proliferation	1434:1451	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	10	55	theme	fibroblast	1505:1514	arg1	cells					1516:1520	NIH3T3 fibroblast cells	1498:1520	NIH3T3 fibroblast cells	1498:1520	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	3	56	theme	chemical	560:567	arg1	features					569:576	The structural and chemical features	541:576	The structural and chemical features of prepared scaffolds	541:598	The structural and chemical features of prepared scaffolds were studied by the FTIR technique.					
35367272	10	57	from	viability	1485:1493	arg1	presence					1529:1536	the presence	1525:1536	the presence of glutaraldehyde-containing scaffolds	1525:1575	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	6	58	theme	chitosan/cellulose	937:954	arg1	nanocrystals					956:967	The chitosan/cellulose nanocrystals	933:967	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde	933:1006	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	6	58	theme	chitosan/cellulose	937:954	arg1	scaffold					969:976	scaffold	969:976	scaffold	969:976	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	9	59	theme	cell	1349:1352	arg1	viability					1354:1362	cell viability	1349:1362	cell viability	1349:1362	The cell viability and cell attachment results indicated that all four scaffolds support cell proliferation and cell adhesion.					
35367272	10	60	theme	NIH3T3	1498:1503	arg1	cells					1516:1520	NIH3T3 fibroblast cells	1498:1520	NIH3T3 fibroblast cells	1498:1520	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	10	61	theme	glutaraldehyde-containing	1541:1565	arg1	scaffolds					1567:1575	glutaraldehyde-containing scaffolds	1541:1575	glutaraldehyde-containing scaffolds	1541:1575	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	2	62	theme	different	351:359	arg1	scaffolds					361:369	four different scaffolds	346:369	four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods	346:446	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	4	63	theme	scaffold	667:674	arg1	samples					676:682	all scaffold samples	663:682	all scaffold samples	663:682	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	4	63	theme	scaffold	667:674	arg1	networks					713:720	porous three-dimensional networks	688:720	porous three-dimensional networks in which the pores are connected	688:753	FESEM images revealed that all scaffold samples are porous three-dimensional networks in which the pores are connected.					
35367272	5	64	theme	chitosan/cellulose	825:842	arg1	nanocrystals					844:855	chitosan/cellulose nanocrystals	825:855	chitosan/cellulose nanocrystals	825:855	TGA analysis showed that the thermal stability of scaffolds based on chitosan/cellulose nanocrystals has not been changed significantly by using different crosslinking methods.					
35367272	2	65	theme	different	417:425	arg1	methods					440:446	different crosslinking methods	417:446	different crosslinking methods	417:446	Therefore, four different scaffolds based on chitosan/cellulose nanocrystals with different crosslinking methods were fabricated using the freeze-drying method for potential use in bone tissue engineering.					
35367272	1	66	theme	main	255:258	arg1	characteristics					260:274	the main characteristics	251:274	the main characteristics of scaffolds based on chitosan and cellulose nanocrystals	251:332	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	0	67	theme	different	49:57	arg1	agents					72:77	different crosslinking agents	49:77	different crosslinking agents	49:77	Effect of glutaraldehyde and calcium chloride as different crosslinking agents on the characteristics of chitosan/cellulose nanocrystals scaffold.					
35367272	6	68	theme	uncrosslinked	1061:1073	arg1	scaffold					1075:1082	the uncrosslinked scaffold	1057:1082	the uncrosslinked scaffold	1057:1082	The chitosan/cellulose nanocrystals scaffold crosslinked by glutaraldehyde represented the highest compressive strength and the uncrosslinked scaffold showed the highest swelling ratio in comparison to the other scaffolds.					
35367272	10	69	theme	other	1600:1604	arg1	scaffolds					1606:1614	other scaffolds	1600:1614	other scaffolds	1600:1614	However, the viability of NIH3T3 fibroblast cells in the presence of glutaraldehyde-containing scaffolds was lower than that of other scaffolds.					
35367272	1	70	theme	glutaraldehyde	161:174	arg1	cations					188:194	glutaraldehyde and calcium cations	161:194	glutaraldehyde and calcium cations as covalent and ionic crosslinkers	161:229	The effect of glutaraldehyde and calcium cations as covalent and ionic crosslinkers was investigated on the main characteristics of scaffolds based on chitosan and cellulose nanocrystals.					
35367272	8	71	theme	FESEM	1242:1246	arg1	images					1248:1253	FESEM images	1242:1253	FESEM images	1242:1253	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35367272	8	72	theme	good	1313:1316	arg1	ability					1336:1342	good biomineralization ability	1313:1342	good biomineralization ability	1313:1342	FESEM images and EDX analysis confirmed that fabricated scaffolds have good biomineralization ability.					
35043585	2	0	theme	first	356:360	arg1	thing					371:375	the first pressing thing	352:375	the first pressing thing for 3D printing tissue engineering scaffold	352:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	7	1	theme	further	1230:1236	arg1	research					1238:1245	The further research	1226:1245	The further research of chicken embryo allantoic membrane assay and animal experiment	1226:1310	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	2	2	from	promotion	441:449	arg1	scaffold					474:481	the scaffold	470:481	the scaffold	470:481	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	6	3	theme	soy	1128:1130	arg1	protein					1132:1138	soy protein	1128:1138	soy protein	1128:1138	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	1	4	theme	broad	180:184	arg1	interest					195:202	broad research interest	180:202	broad research interest	180:202	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	6	5	dep	cell	1175:1178	arg1	attach					1180:1185	attach	1180:1185	attach	1180:1185	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	7	6	theme	peptide	1473:1479	arg1	powder					1481:1486	soy peptide powder	1469:1486	soy peptide powder	1469:1486	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	4	7	theme	good	774:777	arg1	ability					792:798	good crosslinking ability	774:798	good crosslinking ability	774:798	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	6	8	theme	scaffold	1018:1025	arg1	cytocompatibility					989:1005	the cytocompatibility	985:1005	the cytocompatibility of printed scaffold	985:1025	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	7	9	theme	assay	1284:1288	arg1	research					1238:1245	The further research	1226:1245	The further research of chicken embryo allantoic membrane assay and animal experiment	1226:1310	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	3	10	with	hydrogel	527:534	arg1	protein-rich					541:552	protein-rich	541:552	protein-rich	541:552	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	7	11	theme	embryo	1258:1263	arg1	assay					1284:1288	chicken embryo allantoic membrane assay	1250:1288	chicken embryo allantoic membrane assay	1250:1288	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	7	12	contain	has	1488:1490	arg2	means					1424:1428	means	1424:1428	means	1424:1428	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	7	12	contain	has	1488:1490	arg2	potential					1498:1506	great potential	1492:1506	great potential for angiogenesis	1492:1523	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	7	12	contain	has	1488:1490	arg1	ink					1444:1446	the developed ink	1430:1446	the developed ink with soy protein and soy peptide powder	1430:1486	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	5	13	theme	scaffolds	950:958	arg1	properties					932:941	the physicochemical properties	912:941	the physicochemical properties of the scaffolds	912:958	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	4	14	theme	shear-thinning	692:705	arg1	behavior					707:714	excellent shear-thinning behavior	682:714	excellent shear-thinning behavior	682:714	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	6	15	with	scaffolds	1113:1121	arg1	protein					1132:1138	soy protein	1128:1138	soy protein	1128:1138	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	6	15	with	scaffolds	1113:1121	arg1	powder					1156:1161	soy peptide powder	1144:1161	soy peptide powder	1144:1161	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	7	16	theme	animal	1294:1299	arg1	experiment					1301:1310	animal experiment	1294:1310	animal experiment	1294:1310	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	1	17	theme	research	186:193	arg1	interest					195:202	broad research interest	180:202	broad research interest	180:202	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	6	18	theme	printed	1010:1016	arg1	scaffold					1018:1025	printed scaffold	1010:1025	printed scaffold	1010:1025	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	5	19	theme	physicochemical	916:930	arg1	properties					932:941	the physicochemical properties	912:941	the physicochemical properties of the scaffolds	912:958	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	4	20	theme	crosslinking	779:790	arg1	ability					792:798	good crosslinking ability	774:798	good crosslinking ability	774:798	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	2	21	theme	printing	384:391	arg1	engineering					400:410	3D printing tissue engineering	381:410	3D printing tissue engineering scaffold	381:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	7	22	theme	soy	1453:1455	arg1	protein					1457:1463	soy protein	1453:1463	soy protein	1453:1463	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	2	23	theme	3D	381:382	arg1	engineering					400:410	3D printing tissue engineering	381:410	3D printing tissue engineering scaffold	381:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	0	24	theme	Alginate/Gelatin-Based	0:21	arg1	Hydrogel					23:30	Alginate/Gelatin-Based Hydrogel	0:30	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.	0:132	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	4	25	theme	extrusion-based	737:751	arg1	printing					753:760	extrusion-based printing	737:760	extrusion-based printing	737:760	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	1	26	theme	biomedical	207:216	arg1	engineering					218:228	biomedical engineering	207:228	biomedical engineering	207:228	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	0	27	theme	Soy	37:39	arg1	Powder					57:62	Soy Protein/Peptide Powder	37:62	Soy Protein/Peptide Powder	37:62	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	5	28	theme	macroporous	825:835	arg1	scaffolds					847:855	The macroporous composite scaffolds	821:855	The macroporous composite scaffolds	821:855	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	7	29	theme	allantoic	1265:1273	arg1	assay					1284:1288	chicken embryo allantoic membrane assay	1250:1288	chicken embryo allantoic membrane assay	1250:1288	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	2	30	dep	is	349:350	arg1	thing					371:375	the first pressing thing	352:375	the first pressing thing for 3D printing tissue engineering scaffold	352:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	2	31	theme	other	422:426	arg1	thing					428:432	other thing	422:432	other thing	422:432	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	2	31	theme	other	422:426	arg1	promotion					441:449	the promotion	437:449	the promotion of angiogenesis in the scaffold	437:481	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	4	32	dep	contribute	723:732	arg1	shown					768:772	shown	768:772	contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride	723:818	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	3	33	theme	peptide	640:646	arg1	powder					648:653	soy protein/soy peptide powder	624:653	soy protein/soy peptide powder	624:653	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	3	34	theme	gelatin/sodium	497:510	arg1	hydrogel					527:534	a gelatin/sodium alginate-based hydrogel	495:534	a gelatin/sodium alginate-based hydrogel with protein-rich	495:552	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	4	35	theme	excellent	682:690	arg1	behavior					707:714	excellent shear-thinning behavior	682:714	excellent shear-thinning behavior	682:714	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	6	36	theme	peptide	1148:1154	arg1	powder					1156:1161	soy peptide powder	1144:1161	soy peptide powder	1144:1161	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	6	37	theme	epidermal	1074:1082	arg1	cells					1084:1088	human umbilical vein epidermal cells	1053:1088	human umbilical vein epidermal cells	1053:1088	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	7	38	theme	neo-vessels	1389:1399	arg1	growth					1379:1384	the growth	1375:1384	the growth of neo-vessels	1375:1399	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	4	39	theme	prepared	660:667	arg1	inks					669:672	The prepared inks	656:672	The prepared inks	656:672	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	1	40	theme	clinical	234:241	arg1	applications					243:254	clinical applications	234:254	clinical applications	234:254	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	2	41	theme	tissue	393:398	arg1	engineering					400:410	3D printing tissue engineering	381:410	3D printing tissue engineering scaffold	381:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	7	42	theme	soy	1469:1471	arg1	powder					1481:1486	soy peptide powder	1469:1486	soy peptide powder	1469:1486	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	0	43	theme	Protein/Peptide	41:55	arg1	Powder					57:62	Soy Protein/Peptide Powder	37:62	Soy Protein/Peptide Powder	37:62	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	3	44	theme	soy	624:626	arg1	powder					648:653	soy protein/soy peptide powder	624:653	soy protein/soy peptide powder	624:653	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	5	45	theme	composite	837:845	arg1	scaffolds					847:855	The macroporous composite scaffolds	821:855	The macroporous composite scaffolds	821:855	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	2	46	theme	engineering	400:410	arg1	scaffold					412:419	3D printing tissue engineering scaffold	381:419	3D printing tissue engineering scaffold	381:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	2	47	theme	angiogenesis	454:465	arg1	thing					428:432	other thing	422:432	other thing	422:432	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	2	47	theme	angiogenesis	454:465	arg1	promotion					441:449	the promotion	437:449	the promotion of angiogenesis in the scaffold	437:481	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	6	48	theme	vein	1069:1072	arg1	cells					1084:1088	human umbilical vein epidermal cells	1053:1088	human umbilical vein epidermal cells	1053:1088	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	0	49	theme	Printing	71:78	arg1	Scaffolds					99:107	3D Printing Tissue-Engineering Scaffolds	68:107	3D Printing Tissue-Engineering Scaffolds	68:107	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	1	50	theme	recent	137:142	arg1	years					144:148	recent years	137:148	recent years	137:148	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	7	51	with	ink	1444:1446	arg1	protein					1457:1463	soy protein	1453:1463	soy protein	1453:1463	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	7	51	with	ink	1444:1446	arg1	powder					1481:1486	soy peptide powder	1469:1486	soy peptide powder	1469:1486	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	3	52	theme	protein/soy	628:638	arg1	powder					648:653	soy protein/soy peptide powder	624:653	soy protein/soy peptide powder	624:653	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	0	53	with	Hydrogel	23:30	arg1	Powder					57:62	Soy Protein/Peptide Powder	37:62	Soy Protein/Peptide Powder	37:62	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	2	54	theme	ink	345:347	arg1	development					330:340	the development	326:340	the development of ink	326:347	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	7	55	theme	membrane	1275:1282	arg1	assay					1284:1288	chicken embryo allantoic membrane assay	1250:1288	chicken embryo allantoic membrane assay	1250:1288	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	4	56	theme	calcium	803:809	arg1	chloride					811:818	calcium chloride	803:818	calcium chloride	803:818	The prepared inks exhibit excellent shear-thinning behavior, which contribute to extrusion-based printing; also shown good crosslinking ability by calcium chloride.					
35043585	6	57	theme	soy	1144:1146	arg1	powder					1156:1161	soy peptide powder	1144:1161	soy peptide powder	1144:1161	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	5	58	theme	developed	894:902	arg1	ink					904:906	the developed ink	890:906	the developed ink	890:906	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	6	59	theme	umbilical	1059:1067	arg1	cells					1084:1088	human umbilical vein epidermal cells	1053:1088	human umbilical vein epidermal cells	1053:1088	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	6	60	dep	cells	1084:1088	arg1	show					1099:1102	show	1099:1102	show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation	1099:1223	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	7	61	theme	great	1492:1496	arg1	potential					1498:1506	great potential	1492:1506	great potential for angiogenesis	1492:1523	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	7	62	theme	developed	1434:1442	arg1	ink					1444:1446	the developed ink	1430:1446	the developed ink with soy protein and soy peptide powder	1430:1486	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	1	63	theme	3D	151:152	arg1	bioprinting					154:164	3D bioprinting	151:164	3D bioprinting	151:164	In recent years, 3D bioprinting has attracted broad research interest in biomedical engineering and clinical applications.					
35043585	6	64	theme	human	1053:1057	arg1	cells					1084:1088	human umbilical vein epidermal cells	1053:1088	human umbilical vein epidermal cells	1053:1088	Moreover, the cytocompatibility of printed scaffold is characterized by using human umbilical vein epidermal cells, results show that the scaffolds with soy protein and soy peptide powder can promote cell attach, spread, migration, and proliferation.					
35043585	0	65	theme	Tissue-Engineering	80:97	arg1	Scaffolds					99:107	3D Printing Tissue-Engineering Scaffolds	68:107	3D Printing Tissue-Engineering Scaffolds	68:107	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	5	66	theme	3D	872:873	arg1	printing					875:882	3D printing	872:882	3D printing using the developed ink	872:906	The macroporous composite scaffolds are printed by 3D printing using the developed ink and the physicochemical properties of the scaffolds are evaluated.					
35043585	3	67	theme	sodium	603:608	arg1	alginate					610:617	sodium alginate	603:617	sodium alginate	603:617	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	3	68	theme	alginate-based	512:525	arg1	hydrogel					527:534	a gelatin/sodium alginate-based hydrogel	495:534	a gelatin/sodium alginate-based hydrogel with protein-rich	495:552	Therefore, a gelatin/sodium alginate-based hydrogel with protein-rich is developed here, which is prepared by gelatin, sodium alginate, and soy protein/soy peptide powder.					
35043585	2	69	dep	are	272:274	arg1	need					287:290	need	287:290	are two issues need to be solved urgently at present	272:323	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	0	70	theme	3D	68:69	arg1	Scaffolds					99:107	3D Printing Tissue-Engineering Scaffolds	68:107	3D Printing Tissue-Engineering Scaffolds	68:107	Alginate/Gelatin-Based Hydrogel with Soy Protein/Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis.					
35043585	7	71	theme	experiment	1301:1310	arg1	research					1238:1245	The further research	1226:1245	The further research of chicken embryo allantoic membrane assay and animal experiment	1226:1310	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35043585	2	72	theme	pressing	362:369	arg1	thing					371:375	the first pressing thing	352:375	the first pressing thing for 3D printing tissue engineering scaffold	352:419	However, there are two issues need to be solved urgently at present, the development of ink is the first pressing thing for 3D printing tissue engineering scaffold, other thing is the promotion of angiogenesis in the scaffold.					
35043585	7	73	theme	chicken	1250:1256	arg1	assay					1284:1288	chicken embryo allantoic membrane assay	1250:1288	chicken embryo allantoic membrane assay	1250:1288	The further research of chicken embryo allantoic membrane assay and animal experiment are carried, and results present that the scaffold can promote the growth of neo-vessels in the scaffold, which means the developed ink with soy protein and soy peptide powder has great potential for angiogenesis.					
35550506	5	0	theme	chiral	815:820	arg1	bundles					784:790	bundles	784:790	These 'bundles'	777:791	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	0	theme	chiral	815:820	arg1	dopants					822:828	colloidal chiral dopants	805:828	colloidal chiral dopants	805:828	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	4	1	theme	composite	756:764	arg1	particles					766:774	laterally-bound composite particles	740:774	laterally-bound composite particles	740:774	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	5	2	from	link	907:910	arg1	molecular					963:971	molecular	963:971	molecular	963:971	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	2	from	link	907:910	arg1	transfer					932:939	the hierarchical transfer	915:939	the hierarchical transfer of chirality from the molecular to the colloidal scale	915:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	1	3	theme	natural	159:165	arg1	phenomenon					167:176	an intriguing and universal natural phenomenon	131:176	phenomenon	167:176	The transfer of chirality across length-scales is an intriguing and universal natural phenomenon.					
35550506	4	4	from	behaviour	544:552	arg1	films					573:577	films	573:577	films	573:577	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	4	4	from	behaviour	544:552	arg1	suspensions					557:567	suspensions	557:567	suspensions	557:567	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	4	5	theme	laterally-bound	740:754	arg1	particles					766:774	laterally-bound composite particles	740:774	laterally-bound composite particles	740:774	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	3	6	theme	cellulose	398:406	arg1	suspensions					420:430	cellulose nanocrystal suspensions	398:430	cellulose nanocrystal suspensions	398:430	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	4	7	theme	nanoparticles	640:652	arg1	analysis					613:620	a quantitative morphological analysis	584:620	a quantitative morphological analysis of the individual nanoparticles	584:652	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	2	8	theme	structure	300:308	arg1	features					260:267	the emergent features	247:267	the emergent features of their resulting large-scale structure	247:308	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	4	9	theme	individual	629:638	arg1	nanoparticles					640:652	the individual nanoparticles	625:652	the individual nanoparticles	625:652	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	4	10	theme	inverse	668:674	arg1	relationship					676:687	an inverse relationship	665:687	an inverse relationship between the cholesteric pitch	665:717	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	2	11	theme	large-scale	288:298	arg1	structure					300:308	their resulting large-scale structure	272:308	their resulting large-scale structure	272:308	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	3	12	theme	chiral	458:463	arg1	films					474:478	chiral photonic films	458:478	chiral photonic films	458:478	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	5	13	from	molecular	963:971	arg1	link					907:910	the missing link	895:910	the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale	895:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	13	from	molecular	963:971	arg1	transfer					932:939	the hierarchical transfer	915:939	the hierarchical transfer of chirality from the molecular to the colloidal scale	915:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	2	14	theme	resulting	278:286	arg1	structure					300:308	their resulting large-scale structure	272:308	their resulting large-scale structure	272:308	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	3	15	theme	photonic	465:472	arg1	films					474:478	chiral photonic films	458:478	chiral photonic films	458:478	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	0	16	theme	Chiral	0:5	arg1	self-assembly					7:19	Chiral self-assembly	0:19	Chiral self-assembly of cellulose nanocrystals	0:45	Chiral self-assembly of cellulose nanocrystals is driven by crystallite bundles.					
35550506	4	17	theme	quantitative	586:597	arg1	analysis					613:620	a quantitative morphological analysis	584:620	a quantitative morphological analysis of the individual nanoparticles	584:652	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	5	18	theme	missing	899:905	arg1	link					907:910	the missing link	895:910	the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale	895:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	19	theme	colloidal	980:988	arg1	scale					990:994	the colloidal scale	976:994	the colloidal scale	976:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	3	20	theme	mesophase	375:383	arg1	chirality					385:393	mesophase chirality	375:393	mesophase chirality	375:393	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	1	21	theme	chirality	97:105	arg1	intriguing					134:143	intriguing	134:143	intriguing	134:143	The transfer of chirality across length-scales is an intriguing and universal natural phenomenon.					
35550506	1	21	theme	chirality	97:105	arg1	transfer					85:92	The transfer	81:92	The transfer of chirality across length-scales	81:126	The transfer of chirality across length-scales is an intriguing and universal natural phenomenon.					
35550506	3	22	theme	chirality	385:393	arg1	origins					364:370	the origins	360:370	the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest	360:513	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	5	23	theme	chirality	944:952	arg1	transfer					932:939	the hierarchical transfer	915:939	the hierarchical transfer of chirality from the molecular to the colloidal scale	915:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	3	24	theme	significant	494:504	arg1	interest					506:513	significant interest	494:513	significant interest	494:513	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	4	25	theme	morphological	599:611	arg1	analysis					613:620	a quantitative morphological analysis	584:620	a quantitative morphological analysis of the individual nanoparticles	584:652	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	0	26	theme	nanocrystals	34:45	arg1	self-assembly					7:19	Chiral self-assembly	0:19	Chiral self-assembly of cellulose nanocrystals	0:45	Chiral self-assembly of cellulose nanocrystals is driven by crystallite bundles.					
35550506	5	27	theme	analogous	831:839	arg1	bundles					784:790	bundles	784:790	These 'bundles'	777:791	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	27	theme	analogous	831:839	arg1	dopants					822:828	colloidal chiral dopants	805:828	colloidal chiral dopants	805:828	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	3	28	from	origins	364:370	arg1	suspensions					420:430	cellulose nanocrystal suspensions	398:430	cellulose nanocrystal suspensions	398:430	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	0	29	theme	cellulose	24:32	arg1	nanocrystals					34:45	cellulose nanocrystals	24:45	cellulose nanocrystals	24:45	Chiral self-assembly of cellulose nanocrystals is driven by crystallite bundles.					
35550506	5	30	theme	molecular	858:866	arg1	crystals					875:882	molecular liquid crystals	858:882	molecular liquid crystals	858:882	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	3	31	theme	nanocrystal	408:418	arg1	suspensions					420:430	cellulose nanocrystal suspensions	398:430	cellulose nanocrystal suspensions	398:430	In this work, we investigate the origins of mesophase chirality in cellulose nanocrystal suspensions, whose self-assembly into chiral photonic films has attracted significant interest.					
35550506	5	32	theme	colloidal	805:813	arg1	bundles					784:790	bundles	784:790	These 'bundles'	777:791	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	32	theme	colloidal	805:813	arg1	dopants					822:828	colloidal chiral dopants	805:828	colloidal chiral dopants	805:828	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	2	33	theme	blocks	237:242	arg1	properties					203:212	the properties	199:212	the properties of individual building blocks	199:242	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	2	34	theme	individual	217:226	arg1	blocks					237:242	individual building blocks	217:242	individual building blocks	217:242	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	2	35	theme	building	228:235	arg1	blocks					237:242	individual building blocks	217:242	individual building blocks	217:242	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	4	36	theme	particles	766:774	arg1	abundance					727:735	the abundance	723:735	the abundance of laterally-bound composite particles	723:774	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	4	36	theme	particles	766:774	arg1	relationship					676:687	an inverse relationship	665:687	an inverse relationship between the cholesteric pitch	665:717	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	5	37	theme	liquid	868:873	arg1	crystals					875:882	molecular liquid crystals	858:882	molecular liquid crystals	858:882	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	5	38	theme	hierarchical	919:930	arg1	transfer					932:939	the hierarchical transfer	915:939	the hierarchical transfer of chirality from the molecular to the colloidal scale	915:994	These 'bundles' thus act as colloidal chiral dopants, analogous to those used in molecular liquid crystals, providing the missing link in the hierarchical transfer of chirality from the molecular to the colloidal scale.					
35550506	4	39	theme	cholesteric	701:711	arg1	pitch					713:717	the cholesteric pitch	697:717	the cholesteric pitch	697:717	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	0	40	theme	crystallite	60:70	arg1	bundles					72:78	crystallite bundles	60:78	crystallite bundles	60:78	Chiral self-assembly of cellulose nanocrystals is driven by crystallite bundles.					
35550506	4	41	theme	ensemble	535:542	arg1	behaviour					544:552	the ensemble behaviour	531:552	the ensemble behaviour in suspensions and films	531:577	By correlating the ensemble behaviour in suspensions and films with a quantitative morphological analysis of the individual nanoparticles, we reveal an inverse relationship between the cholesteric pitch and the abundance of laterally-bound composite particles.					
35550506	2	42	theme	emergent	251:258	arg1	features					260:267	the emergent features	247:267	the emergent features of their resulting large-scale structure	247:308	However, connecting the properties of individual building blocks to the emergent features of their resulting large-scale structure remains a challenge.					
35550506	1	43	theme	universal	149:157	arg1	phenomenon					167:176	an intriguing and universal natural phenomenon	131:176	phenomenon	167:176	The transfer of chirality across length-scales is an intriguing and universal natural phenomenon.					
37028630	0	0	theme	cooking	70:76	arg1	quality					78:84	the edible and cooking quality	55:84	the edible and cooking quality of its porridge	55:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	1	1	dep	storage	272:278	arg1	40 °C					281:285	40 °C	281:285	40 °C	281:285	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	1	1	dep	storage	272:278	arg1	10 weeks					288:295	10 weeks	288:295	10 weeks	288:295	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	3	2	dep	homogeneity	516:526	arg1	the					512:514	the	512:514	the	512:514	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	8	3	theme	millet	1469:1474	arg1	G					1437:1437	G'	1437:1438	G'	1437:1438	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	8	3	theme	millet	1469:1474	arg1	G″					1444:1445	G″	1444:1445	G″	1444:1445	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	2	4	theme	foxtail	430:436	arg1	millet					438:443	foxtail millet	430:443	foxtail millet	430:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	1	5	theme	foxtail	301:307	arg1	millet					309:314	foxtail millet	301:314	foxtail millet	301:314	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	2	6	dep	protein	408:414	arg1	in-situ					400:406	the in-situ protein and starch in foxtail millet	396:443	the in-situ protein and starch in foxtail millet	396:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	4	7	dep	absorption	733:742	arg1	the					723:725	the	723:725	the	723:725	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	2	8	from	millet	438:443	arg1	alteration					382:391	The structural alteration	367:391	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties	367:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	2	9	theme	physicochemical	461:475	arg1	properties					477:486	the physicochemical properties	457:486	the physicochemical properties	457:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	1	10	theme	millet	309:314	arg1	storage					272:278	the accelerating storage	255:278	the accelerating storage (40 °C, 10 weeks) of foxtail millet	255:314	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	7	11	theme	stored	1253:1258	arg1	sample					1260:1265	the stored sample	1249:1265	the stored sample	1249:1265	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	7	12	theme	native	1176:1181	arg1	millet					1191:1196	the native foxtail millet	1172:1196	the native foxtail millet	1172:1196	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	5	13	theme	protein	1012:1018	arg1	bodies					1020:1025	protein bodies	1012:1025	protein bodies	1012:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	0	14	theme	protein	160:166	arg1	alteration					134:143	the structural alteration	119:143	the structural alteration of the in-situ protein and starch and physicochemical properties	119:208	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	5	15	theme	stored	896:901	arg1	millet					903:908	the stored millet	892:908	the stored millet	892:908	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	8	16	theme	native	1511:1516	arg1	counterpart					1518:1528	its native counterpart	1507:1528	its native counterpart	1507:1528	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	0	17	theme	porridge	93:100	arg1	quality					78:84	the edible and cooking quality	55:84	the edible and cooking quality of its porridge	55:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	2	18	from	protein	408:414	arg1	millet					438:443	foxtail millet	430:443	foxtail millet	430:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	6	19	theme	stored	1087:1092	arg1	millet					1094:1099	the stored millet	1083:1099	the stored millet	1083:1099	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	8	20	theme	foxtail	1461:1467	arg1	millet					1469:1474	the stored foxtail millet	1450:1474	the stored foxtail millet	1450:1474	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	0	21	theme	millet	45:50	arg1	storage					26:32	accelerating storage	13:32	accelerating storage of foxtail millet	13:50	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	1	22	theme	edible	323:328	arg1	quality					342:348	the edible and cooking quality	319:348	the edible and cooking quality of its porridge	319:364	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	0	23	theme	starch	172:177	arg1	alteration					134:143	the structural alteration	119:143	the structural alteration of the in-situ protein and starch and physicochemical properties	119:208	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	2	24	from	starch	420:425	arg1	millet					438:443	foxtail millet	430:443	foxtail millet	430:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	0	25	theme	properties	199:208	arg1	alteration					134:143	the structural alteration	119:143	the structural alteration of the in-situ protein and starch and physicochemical properties	119:208	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	5	26	with	gelatinization	961:974	arg1	extension					999:1007	a higher coverage extension	981:1007	a higher coverage extension in protein bodies	981:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	0	27	theme	physicochemical	183:197	arg1	properties					199:208	physicochemical properties	183:208	physicochemical properties	183:208	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	5	28	theme	starch	873:878	arg1	granules					880:887	the starch granules	869:887	the starch granules in the stored millet	869:908	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	5	29	theme	coverage	990:997	arg1	extension					999:1007	a higher coverage extension	981:1007	a higher coverage extension in protein bodies	981:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	0	30	theme	storage	26:32	arg1	Influence					0:8	Influence	0:8	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge	0:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	7	31	theme	sample	1260:1265	arg1	trough					1209:1214	trough	1209:1214	trough	1209:1214	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	7	31	theme	sample	1260:1265	arg1	peak					1203:1206	the peak	1199:1206	the peak	1199:1206	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	7	31	theme	sample	1260:1265	arg1	viscosity					1236:1244	setback viscosity	1228:1244	setback viscosity	1228:1244	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	4	32	theme	water	727:731	arg1	absorption					733:742	water absorption	727:742	water absorption	727:742	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	5	33	theme	better	954:959	arg1	gelatinization					961:974	better gelatinization	954:974	better gelatinization with a higher coverage extension in protein bodies	954:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	2	34	theme	structural	371:380	arg1	alteration					382:391	The structural alteration	367:391	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties	367:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	0	35	theme	accelerating	13:24	arg1	storage					26:32	accelerating storage	13:32	accelerating storage of foxtail millet	13:50	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	1	36	theme	accelerating	259:270	arg1	storage					272:278	the accelerating storage	255:278	the accelerating storage (40 °C, 10 weeks) of foxtail millet	255:314	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	1	37	from	effect	245:250	arg1	quality					342:348	the edible and cooking quality	319:348	the edible and cooking quality of its porridge	319:364	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	1	38	theme	cooking	334:340	arg1	quality					342:348	the edible and cooking quality	319:348	the edible and cooking quality of its porridge	319:364	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	6	39	theme	protein	1057:1063	arg1	bonds					1074:1078	the protein hydrogen bonds	1053:1078	the protein hydrogen bonds in the stored millet	1053:1099	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	0	40	dep	protein	160:166	arg1	in-situ					152:158	the in-situ protein and starch	148:177	the in-situ protein and starch	148:177	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	0	41	theme	foxtail	37:43	arg1	millet					45:50	foxtail millet	37:50	foxtail millet	37:50	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	1	42	theme	storage	272:278	arg1	effect					245:250	the effect	241:250	the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge	241:364	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	3	43	theme	millet	616:621	arg1	storage					605:611	8-week storage	598:611	8-week storage of millet	598:621	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	3	44	theme	millet	548:553	arg1	porridge					555:562	millet porridge	548:562	millet porridge	548:562	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	6	45	from	bonds	1074:1078	arg1	millet					1094:1099	the stored millet	1083:1099	the stored millet	1083:1099	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	2	46	theme	starch	420:425	arg1	alteration					382:391	The structural alteration	367:391	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties	367:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	2	47	theme	properties	477:486	arg1	alteration					382:391	The structural alteration	367:391	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties	367:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	3	48	theme	8-week	598:603	arg1	storage					605:611	8-week storage	598:611	8-week storage of millet	598:621	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	3	49	theme	porridge	555:562	arg1	palatability					532:543	palatability	532:543	palatability	532:543	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	3	49	theme	porridge	555:562	arg1	homogeneity					516:526	homogeneity	516:526	homogeneity	516:526	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	5	50	theme	morphological	803:815	arg1	studies					817:823	The morphological studies	799:823	The morphological studies (using the SEM, CLSM and TEM)	799:853	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	5	51	theme	higher	983:988	arg1	extension					999:1007	a higher coverage extension	981:1007	a higher coverage extension in protein bodies	981:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	5	52	from	extension	999:1007	arg1	bodies					1020:1025	protein bodies	1012:1025	protein bodies	1012:1025	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	0	53	theme	structural	123:132	arg1	alteration					134:143	the structural alteration	119:143	the structural alteration of the in-situ protein and starch and physicochemical properties	119:208	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	7	54	theme	conclusion	1350:1359	arg1	temperature					1361:1371	conclusion temperature	1350:1371	conclusion temperature	1350:1371	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	2	55	from	alteration	382:391	arg1	millet					438:443	foxtail millet	430:443	foxtail millet	430:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	0	56	from	Influence	0:8	arg1	quality					78:84	the edible and cooking quality	55:84	the edible and cooking quality of its porridge	55:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	1	57	theme	porridge	357:364	arg1	quality					342:348	the edible and cooking quality	319:348	the edible and cooking quality of its porridge	319:364	This study aimed to elucidate the effect of the accelerating storage (40 °C, 10 weeks) of foxtail millet on the edible and cooking quality of its porridge.					
37028630	6	58	theme	ordered	1132:1138	arg1	degree					1140:1145	the starch ordered degree	1121:1145	the starch ordered degree	1121:1145	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	3	59	gly	homogeneity	516:526	arg1	porridge					555:562	millet porridge	548:562	millet porridge	548:562	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	5	60	from	granules	880:887	arg1	millet					903:908	the stored millet	892:908	the stored millet	892:908	The morphological studies (using the SEM, CLSM and TEM) revealed that the starch granules in the stored millet became easier to swell and melt, leading to better gelatinization with a higher coverage extension in protein bodies.					
37028630	3	61	theme	proximate	634:642	arg1	compositions					644:655	its proximate compositions	630:655	its proximate compositions	630:655	Both the homogeneity and palatability of millet porridge were significantly improved after 8-week storage of millet, while its proximate compositions remained unchanged.					
37028630	6	62	theme	starch	1125:1130	arg1	degree					1140:1145	the starch ordered degree	1121:1145	the starch ordered degree	1121:1145	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	4	63	theme	accelerating	692:703	arg1	storage					705:711	the accelerating storage	688:711	the accelerating storage	688:711	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	4	63	theme	accelerating	692:703	arg1	Meanwhile					677:685	Meanwhile	677:685	Meanwhile	677:685	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	6	64	theme	hydrogen	1065:1072	arg1	bonds					1074:1078	the protein hydrogen bonds	1053:1078	the protein hydrogen bonds in the stored millet	1053:1099	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	8	65	dep	G	1437:1437	arg1	the					1433:1435	the	1433:1435	the	1433:1435	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	4	66	theme	millet	760:765	arg1	swelling					748:755	swelling	748:755	swelling	748:755	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	4	66	theme	millet	760:765	arg1	absorption					733:742	water absorption	727:742	water absorption	727:742	Meanwhile, the accelerating storage increased the water absorption and swelling of millet by 20 % and 22 %, respectively.					
37028630	7	67	theme	foxtail	1183:1189	arg1	millet					1191:1196	the native foxtail millet	1172:1196	the native foxtail millet	1172:1196	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	2	68	theme	protein	408:414	arg1	alteration					382:391	The structural alteration	367:391	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties	367:486	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	2	69	from	properties	477:486	arg1	millet					438:443	foxtail millet	430:443	foxtail millet	430:443	The structural alteration of the in-situ protein and starch in foxtail millet, as well as the physicochemical properties were investigated.					
37028630	0	70	theme	edible	59:64	arg1	quality					78:84	the edible and cooking quality	55:84	the edible and cooking quality of its porridge	55:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37028630	7	71	theme	setback	1228:1234	arg1	viscosity					1236:1244	setback viscosity	1228:1244	setback viscosity	1228:1244	Compared to the native foxtail millet, the peak, trough, final, and setback viscosity of the stored sample increased by 27 %, 76 %, 115 % and 143 %, respectively, while the onset, peak, and conclusion temperature increased by 0.80, 1.10 and 0.80 °C, respectively.					
37028630	6	72	theme	FTIR	1028:1031	arg1	results					1033:1039	FTIR results	1028:1039	FTIR results	1028:1039	FTIR results showed that the protein hydrogen bonds in the stored millet became stronger and the starch ordered degree was reduced.					
37028630	8	73	theme	stored	1454:1459	arg1	millet					1469:1474	the stored foxtail millet	1450:1474	the stored foxtail millet	1450:1474	Besides, the G' and G″ of the stored foxtail millet were significantly higher than its native counterpart.					
37028630	0	74	dep	insight	106:112	arg1	Influence					0:8	Influence	0:8	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge	0:100	Influence of accelerating storage of foxtail millet on the edible and cooking quality of its porridge: An insight into the structural alteration of the in-situ protein and starch and physicochemical properties.					
37364804	11	0	theme	biomaterials	1965:1976	arg1	class					1948:1952	a new class	1942:1952	a new class of natural biomaterials for tissue engineering	1942:1999	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	5	1	theme	macrophages	780:790	arg1	phenotype					767:775	the phenotype	763:775	the phenotype of macrophages	763:790	In a nutshell, gHECM promotes tissue regeneration by changing the phenotype of macrophages around the site of injury.					
37364804	6	2	theme	anti-inflammatory	1044:1060	arg1	cytokines					1062:1070	anti-inflammatory cytokines	1044:1070	anti-inflammatory cytokines	1044:1070	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	0	3	theme	M2-type	94:100	arg1	polarization					102:113	M2-type polarization	94:113	M2-type polarization of macrophages	94:128	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	7	4	theme	spatial	1178:1184	arg1	barriers					1186:1193	spatial barriers	1178:1193	spatial barriers	1178:1193	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	4	5	from	aids	551:554	arg1	regeneration					563:574	the regeneration	559:574	the regeneration of the gastric lining	559:596	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	7	6	theme	inflammation	1325:1336	arg1	recovery					1313:1320	the recovery	1309:1320	the recovery of inflammation and healing of ulcers	1309:1358	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	0	7	theme	macrophages	118:128	arg1	polarization					102:113	M2-type polarization	94:113	M2-type polarization of macrophages	94:128	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	10	8	theme	signaling	1674:1682	arg1	pathways					1684:1691	the signaling pathways	1670:1691	the signaling pathways involved in this process	1670:1716	Nevertheless, the signaling pathways involved in this process need to be further explored and identified.					
37364804	4	9	theme	surrounding	627:637	arg1	macrophages					639:649	surrounding macrophages	627:649	surrounding macrophages	627:649	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	8	10	theme	chemotactic	1444:1454	arg1	ability					1456:1462	the chemotactic ability	1440:1462	the chemotactic ability of macrophages	1440:1477	They contribute to the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion.					
37364804	4	11	from	inflammation	534:545	arg1	regeneration					563:574	the regeneration	559:574	the regeneration of the gastric lining	559:596	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	7	12	theme	peripheral	1211:1220	arg1	system					1229:1234	the peripheral immune system	1207:1234	the peripheral immune system	1207:1234	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	8	13	theme	local	1415:1419	arg1	tissues					1421:1427	local tissues	1415:1427	local tissues	1415:1427	They contribute to the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion.					
37364804	2	14	theme	decellularized	336:349	arg1	matrix					365:370	a gastric submucosal decellularized extracellular matrix	315:370	a gastric submucosal decellularized extracellular matrix called gHECM	315:383	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	7	15	theme	inflammatory	1253:1264	arg1	microenvironment					1266:1281	the inflammatory microenvironment	1249:1281	the inflammatory microenvironment	1249:1281	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	6	16	theme	macrophages	925:935	arg1	percentage					908:917	the percentage	904:917	the percentage of M1 macrophages	904:935	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	6	17	theme	NF-κB	1095:1099	arg1	pathway					1101:1107	the NF-κB pathway	1091:1107	the NF-κB pathway	1091:1107	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	2	18	theme	acid	292:295	arg1	layer					272:276	a drug-carrying layer	256:276	a drug-carrying layer of hyaluronic acid	256:295	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	0	19	theme	matrix	59:64	arg1	composite					66:74	hyaluronic acid/extracellular matrix composite	29:74	hyaluronic acid/extracellular matrix composite	29:74	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	6	20	theme	M1	922:923	arg1	macrophages					925:935	M1 macrophages	922:935	M1 macrophages	922:935	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	5	21	theme	injury	811:816	arg1	injury					811:816	injury	811:816	injury	811:816	In a nutshell, gHECM promotes tissue regeneration by changing the phenotype of macrophages around the site of injury.					
37364804	5	21	theme	injury	811:816	arg1	site					803:806	the site	799:806	the site of injury	799:816	In a nutshell, gHECM promotes tissue regeneration by changing the phenotype of macrophages around the site of injury.					
37364804	2	22	theme	hyaluronic	281:290	arg1	acid					292:295	hyaluronic acid	281:295	hyaluronic acid	281:295	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	0	23	theme	gastric	10:16	arg1	ulcer					18:22	gastric ulcer	10:22	gastric ulcer	10:22	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	11	24	theme	new	1944:1946	arg1	class					1948:1952	a new class	1942:1952	a new class of natural biomaterials for tissue engineering	1942:1999	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	11	25	theme	decellularized	1902:1915	arg1	matrix					1917:1922	the decellularized matrix	1898:1922	the decellularized matrix	1898:1922	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	2	26	theme	submucosal	325:334	arg1	matrix					365:370	a gastric submucosal decellularized extracellular matrix	315:370	a gastric submucosal decellularized extracellular matrix called gHECM	315:383	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	7	27	theme	ulcers	1353:1358	arg1	healing					1342:1348	healing	1342:1348	healing	1342:1348	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	7	27	theme	ulcers	1353:1358	arg1	inflammation					1325:1336	inflammation	1325:1336	inflammation	1325:1336	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	4	28	theme	lining	591:596	arg1	regeneration					563:574	the regeneration	559:574	the regeneration of the gastric lining	559:596	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	2	29	theme	gastric	317:323	arg1	matrix					365:370	a gastric submucosal decellularized extracellular matrix	315:370	a gastric submucosal decellularized extracellular matrix called gHECM	315:383	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	4	30	theme	macrophages	639:649	arg1	phenotype					614:622	the phenotype	610:622	the phenotype of surrounding macrophages	610:649	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	4	31	theme	gastric	583:589	arg1	lining					591:596	the gastric lining	579:596	the gastric lining	579:596	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	5	32	theme	tissue	731:736	arg1	regeneration					738:749	tissue regeneration	731:749	tissue regeneration	731:749	In a nutshell, gHECM promotes tissue regeneration by changing the phenotype of macrophages around the site of injury.					
37364804	8	33	theme	paracrine	1487:1495	arg1	secretion					1497:1505	paracrine secretion	1487:1505	paracrine secretion	1487:1505	They contribute to the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion.					
37364804	9	34	theme	immunological	1541:1553	arg1	network					1566:1572	the immunological regulatory network	1537:1572	the immunological regulatory network of macrophage polarization	1537:1599	In this study, we focused on the immunological regulatory network of macrophage polarization to further develop the mechanisms behind this process.					
37364804	3	35	theme	macrophage	404:413	arg1	polarization					415:426	macrophage polarization	404:426	macrophage polarization	404:426	The regulation of macrophage polarization by the extracellular matrix's components was then investigated.					
37364804	6	36	theme	M2	1012:1013	arg1	phenotype					1015:1023	the M2 phenotype	1008:1023	the M2 phenotype	1008:1023	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	9	37	theme	polarization	1588:1599	arg1	network					1566:1572	the immunological regulatory network	1537:1572	the immunological regulatory network of macrophage polarization	1537:1599	In this study, we focused on the immunological regulatory network of macrophage polarization to further develop the mechanisms behind this process.					
37364804	1	38	theme	clinical	222:229	arg1	treatment					135:143	The treatment	131:143	The treatment of gastric ulcer and perforation using synthetic and biomaterials	131:209	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	1	38	theme	clinical	222:229	arg1	challenge					231:239	a clinical challenge	220:239	a clinical challenge	220:239	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	0	39	theme	acid/extracellular	40:57	arg1	composite					66:74	hyaluronic acid/extracellular matrix composite	29:74	hyaluronic acid/extracellular matrix composite	29:74	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	11	40	theme	natural	1957:1963	arg1	biomaterials					1965:1976	natural biomaterials	1957:1976	natural biomaterials for tissue engineering	1957:1999	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	9	41	theme	regulatory	1555:1564	arg1	network					1566:1572	the immunological regulatory network	1537:1572	the immunological regulatory network of macrophage polarization	1537:1599	In this study, we focused on the immunological regulatory network of macrophage polarization to further develop the mechanisms behind this process.					
37364804	8	42	theme	secreted	1384:1391	arg1	cytokines					1393:1401	the secreted cytokines	1380:1401	the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion	1380:1505	They contribute to the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion.					
37364804	4	43	theme	immune	684:689	arg1	response					691:698	the body's whole immune response	667:698	the body's whole immune response	667:698	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	0	44	theme	hyaluronic	29:38	arg1	composite					66:74	hyaluronic acid/extracellular matrix composite	29:74	hyaluronic acid/extracellular matrix composite	29:74	Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.					
37364804	7	45	theme	immune	1222:1227	arg1	system					1229:1234	the peripheral immune system	1207:1234	the peripheral immune system	1207:1234	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	8	46	theme	macrophages	1467:1477	arg1	ability					1456:1462	the chemotactic ability	1440:1462	the chemotactic ability of macrophages	1440:1477	They contribute to the secreted cytokines that act on local tissues or enhance the chemotactic ability of macrophages through paracrine secretion.					
37364804	4	47	theme	whole	678:682	arg1	response					691:698	the body's whole immune response	667:698	the body's whole immune response	667:698	This work proclaims how gHECM responds to inflammation and aids in the regeneration of the gastric lining by altering the phenotype of surrounding macrophages and stimulating the body's whole immune response.					
37364804	6	48	theme	subpopulation	991:1003	arg1	release					1033:1039	the release	1029:1039	the release of anti-inflammatory cytokines, which could block the NF-κB pathway	1029:1107	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	6	48	theme	subpopulation	991:1003	arg1	differentiation					961:975	differentiation	961:975	differentiation of macrophage subpopulation to the M2 phenotype	961:1023	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	7	49	theme	Activated	1110:1118	arg1	macrophages					1120:1130	Activated macrophages	1110:1130	Activated macrophages	1110:1130	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	3	50	theme	extracellular	435:447	arg1	components					458:467	the extracellular matrix's components	431:467	the extracellular matrix's components	431:467	The regulation of macrophage polarization by the extracellular matrix's components was then investigated.					
37364804	6	51	theme	macrophage	980:989	arg1	subpopulation					991:1003	macrophage subpopulation	980:1003	macrophage subpopulation	980:1003	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	6	52	theme	cytokines	883:891	arg1	production					852:861	the production	848:861	the production of pro-inflammatory cytokines	848:891	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	1	53	theme	perforation	166:176	arg1	treatment					135:143	The treatment	131:143	The treatment of gastric ulcer and perforation using synthetic and biomaterials	131:209	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	1	53	theme	perforation	166:176	arg1	challenge					231:239	a clinical challenge	220:239	a clinical challenge	220:239	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	9	54	theme	macrophage	1577:1586	arg1	polarization					1588:1599	macrophage polarization	1577:1599	macrophage polarization	1577:1599	In this study, we focused on the immunological regulatory network of macrophage polarization to further develop the mechanisms behind this process.					
37364804	7	55	theme	healing	1342:1348	arg1	recovery					1313:1320	the recovery	1309:1320	the recovery of inflammation and healing of ulcers	1309:1358	Activated macrophages are capable of immediately delivering through spatial barriers, modulating the peripheral immune system, influencing the inflammatory microenvironment, and ultimately promoting the recovery of inflammation and healing of ulcers.					
37364804	6	56	theme	pro-inflammatory	866:881	arg1	cytokines					883:891	pro-inflammatory cytokines	866:891	pro-inflammatory cytokines	866:891	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	1	57	theme	gastric	148:154	arg1	ulcer					156:160	gastric ulcer	148:160	gastric ulcer	148:160	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	11	58	theme	more	1804:1807	arg1	investigation					1809:1821	more investigation	1804:1821	more investigation into how the decellularized matrix affects immune modulation	1804:1882	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	1	59	theme	ulcer	156:160	arg1	treatment					135:143	The treatment	131:143	The treatment of gastric ulcer and perforation using synthetic and biomaterials	131:209	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	1	59	theme	ulcer	156:160	arg1	challenge					231:239	a clinical challenge	220:239	a clinical challenge	220:239	The treatment of gastric ulcer and perforation using synthetic and biomaterials has been a clinical challenge.					
37364804	2	60	theme	extracellular	351:363	arg1	matrix					365:370	a gastric submucosal decellularized extracellular matrix	315:370	a gastric submucosal decellularized extracellular matrix called gHECM	315:383	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	2	61	theme	drug-carrying	258:270	arg1	layer					272:276	a drug-carrying layer	256:276	a drug-carrying layer of hyaluronic acid	256:295	In this work, a drug-carrying layer of hyaluronic acid was combined with a gastric submucosal decellularized extracellular matrix called gHECM.					
37364804	11	62	theme	tissue	1982:1987	arg1	engineering					1989:1999	tissue engineering	1982:1999	tissue engineering	1982:1999	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	11	63	theme	immune	1866:1871	arg1	modulation					1873:1882	immune modulation	1866:1882	immune modulation	1866:1882	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	11	64	theme	decellularized	1836:1849	arg1	matrix					1851:1856	the decellularized matrix	1832:1856	the decellularized matrix	1832:1856	We think that our research will encourage more investigation into how the decellularized matrix affects immune modulation and will help the decellularized matrix perform better as a new class of natural biomaterials for tissue engineering.					
37364804	3	65	theme	polarization	415:426	arg1	regulation					390:399	The regulation	386:399	The regulation of macrophage polarization by the extracellular matrix's components	386:467	The regulation of macrophage polarization by the extracellular matrix's components was then investigated.					
37364804	6	66	theme	cytokines	1062:1070	arg1	release					1033:1039	the release	1029:1039	the release of anti-inflammatory cytokines, which could block the NF-κB pathway	1029:1107	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
37364804	6	66	theme	cytokines	1062:1070	arg1	differentiation					961:975	differentiation	961:975	differentiation of macrophage subpopulation to the M2 phenotype	961:1023	In particular, gHECM reduces the production of pro-inflammatory cytokines, decreases the percentage of M1 macrophages, and further encourages differentiation of macrophage subpopulation to the M2 phenotype and the release of anti-inflammatory cytokines, which could block the NF-κB pathway.					
35287849	0	0	theme	healing	86:92	arg1	defects					114:120	healing full-thickness skin defects	86:120	healing full-thickness skin defects	86:120	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	7	1	theme	denser	1243:1248	arg1	surface					1256:1262	the denser upper surface outward	1239:1270	the denser upper surface outward	1239:1270	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	3	2	theme	physical	703:710	arg1	barrier					712:718	a physical barrier	701:718	a physical barrier to the invasion of bacteria	701:746	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	1	3	theme	excellent	159:167	arg1	biomaterial					179:189	an excellent candidate biomaterial	156:189	an excellent candidate biomaterial for wound dressing applications	156:221	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	3	theme	excellent	159:167	arg1	nanocellulose					133:145	Bacterial nanocellulose	123:145	Bacterial nanocellulose (BNC)	123:151	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	0	4	theme	skin	109:112	arg1	defects					114:120	healing full-thickness skin defects	86:120	healing full-thickness skin defects	86:120	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	3	5	theme	BNC	578:580	arg1	membranes					582:590	the BNC membranes	574:590	the BNC membranes	574:590	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	0	6	theme	full-thickness	94:107	arg1	defects					114:120	healing full-thickness skin defects	86:120	healing full-thickness skin defects	86:120	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	3	7	theme	bacteria	739:746	arg1	invasion					727:734	the invasion	723:734	the invasion of bacteria	723:746	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	3	8	theme	membranes	582:590	arg1	denser					605:610	denser	605:610	denser	605:610	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	3	8	theme	membranes	582:590	arg1	surfaces					562:569	the upper surfaces	552:569	the upper surfaces of the BNC membranes	552:590	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	1	9	theme	wound	284:288	arg1	healing					290:296	wound healing	284:296	wound healing resulting from BNC biosynthesized by different bacterial strains	284:361	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	2	10	theme	study	369:373	arg1	design					375:380	This study design	364:380	This study design	364:380	This study design aimed to characterize the BNC produced by three different bacterial strains and compare their effectiveness for wound healing applications.					
35287849	7	11	theme	membranes	1200:1208	arg1	surface					1185:1191	the lower surface	1175:1191	the lower surface of BNC membranes	1175:1208	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	6	12	theme	different	1100:1108	arg1	strains					1110:1116	different strains	1100:1116	different strains	1100:1116	The results indicate that BNC biosynthesized by different strains displayed different wound healing effectiveness.					
35287849	4	13	theme	lower	797:801	arg1	surfaces					803:810	the lower surfaces	793:810	the lower surfaces of BNC membranes	793:827	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	1	14	theme	candidate	169:177	arg1	biomaterial					179:189	an excellent candidate biomaterial	156:189	an excellent candidate biomaterial for wound dressing applications	156:221	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	14	theme	candidate	169:177	arg1	nanocellulose					133:145	Bacterial nanocellulose	123:145	Bacterial nanocellulose (BNC)	123:151	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	7	15	theme	lower	1179:1183	arg1	surface					1185:1191	the lower surface	1175:1191	the lower surface of BNC membranes	1175:1208	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	4	16	theme	upper	880:884	arg1	surfaces					886:893	the upper surfaces	876:893	the upper surfaces	876:893	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	5	17	theme	In	896:897	arg1	analysis					904:911	In vivo analysis	896:911	In vivo analysis	896:911	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	1	18	theme	wound	195:199	arg1	applications					210:221	wound dressing applications	195:221	wound dressing applications	195:221	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	0	19	theme	nanocellulose	18:30	arg1	membranes					32:40	wet nanocellulose membranes	14:40	wet nanocellulose membranes	14:40	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	4	20	theme	membranes	819:827	arg1	surfaces					803:810	the lower surfaces	793:810	the lower surfaces of BNC membranes	793:827	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	4	21	theme	fibroblasts	763:773	arg1	growth					753:758	The growth	749:758	The growth of fibroblasts	749:773	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	5	22	dep	In	896:897	arg1	vivo					899:902	vivo	899:902	vivo	899:902	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	1	23	theme	dressing	201:208	arg1	applications					210:221	wound dressing applications	195:221	wound dressing applications	195:221	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	0	24	theme	wet	14:16	arg1	membranes					32:40	wet nanocellulose membranes	14:40	wet nanocellulose membranes	14:40	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	7	25	with	contact	1213:1219	arg1	wounds					1226:1231	wounds	1226:1231	wounds	1226:1231	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	2	26	theme	bacterial	440:448	arg1	strains					450:456	three different bacterial strains	424:456	three different bacterial strains	424:456	This study design aimed to characterize the BNC produced by three different bacterial strains and compare their effectiveness for wound healing applications.					
35287849	5	27	theme	greatest	1020:1027	arg1	efficacy					1042:1049	the greatest wound repair efficacy	1016:1049	the greatest wound repair efficacy	1016:1049	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	7	28	theme	wound	1314:1318	arg1	biomaterial					1327:1337	a wound repair biomaterial	1312:1337	a wound repair biomaterial	1312:1337	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	5	29	theme	wound	1029:1033	arg1	efficacy					1042:1049	the greatest wound repair efficacy	1016:1049	the greatest wound repair efficacy	1016:1049	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	2	30	theme	different	430:438	arg1	strains					450:456	three different bacterial strains	424:456	three different bacterial strains	424:456	This study design aimed to characterize the BNC produced by three different bacterial strains and compare their effectiveness for wound healing applications.					
35287849	2	31	theme	healing	500:506	arg1	applications					508:519	wound healing applications	494:519	wound healing applications	494:519	This study design aimed to characterize the BNC produced by three different bacterial strains and compare their effectiveness for wound healing applications.					
35287849	0	32	theme	membranes	32:40	arg1	Evaluation					0:9	Evaluation	0:9	Evaluation of wet nanocellulose membranes	0:40	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	5	33	theme	repair	1035:1040	arg1	efficacy					1042:1049	the greatest wound repair efficacy	1016:1049	the greatest wound repair efficacy	1016:1049	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	7	34	theme	repair	1320:1325	arg1	biomaterial					1327:1337	a wound repair biomaterial	1312:1337	a wound repair biomaterial	1312:1337	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	2	35	theme	wound	494:498	arg1	applications					508:519	wound healing applications	494:519	wound healing applications	494:519	This study design aimed to characterize the BNC produced by three different bacterial strains and compare their effectiveness for wound healing applications.					
35287849	0	36	theme	bacterial	64:72	arg1	strains					74:80	different bacterial strains	54:80	different bacterial strains for healing full-thickness skin defects	54:120	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	6	37	theme	wound	1138:1142	arg1	effectiveness					1152:1164	different wound healing effectiveness	1128:1164	different wound healing effectiveness	1128:1164	The results indicate that BNC biosynthesized by different strains displayed different wound healing effectiveness.					
35287849	1	38	theme	Bacterial	123:131	arg1	BNC					148:150	BNC	148:150	BNC	148:150	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	38	theme	Bacterial	123:131	arg1	nanocellulose					133:145	Bacterial nanocellulose	123:145	Bacterial nanocellulose (BNC)	123:151	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	38	theme	Bacterial	123:131	arg1	biomaterial					179:189	an excellent candidate biomaterial	156:189	an excellent candidate biomaterial for wound dressing applications	156:221	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	39	from	differences	269:279	arg1	healing					290:296	wound healing	284:296	wound healing resulting from BNC biosynthesized by different bacterial strains	284:361	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	1	40	theme	different	335:343	arg1	strains					355:361	different bacterial strains	335:361	different bacterial strains	335:361	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	4	41	theme	superior	856:863	arg1	biocompatibility					839:854	biocompatibility	839:854	biocompatibility superior to that of the upper surfaces	839:893	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	1	42	theme	bacterial	345:353	arg1	strains					355:361	different bacterial strains	335:361	different bacterial strains	335:361	Bacterial nanocellulose (BNC) is an excellent candidate biomaterial for wound dressing applications, although its preparation should consider the differences in wound healing resulting from BNC biosynthesized by different bacterial strains.					
35287849	7	43	theme	clinical	1287:1294	arg1	requirements					1296:1307	the clinical requirements	1283:1307	the clinical requirements of a wound repair biomaterial	1283:1337	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	7	44	dep	satisfied	1273:1281	arg1	Placing					1167:1173	Placing	1167:1173	Placing the lower surface of BNC membranes in contact with wounds	1167:1231	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	5	45	theme	BNC	969:971	arg1	membrane					973:980	the BNC membrane	965:980	the BNC membrane synthesized by DHU-WX-1	965:1004	In vivo analysis indicated that, of all samples, wounds treated with the BNC membrane synthesized by DHU-WX-1 displayed the greatest wound repair efficacy.					
35287849	6	46	theme	healing	1144:1150	arg1	effectiveness					1152:1164	different wound healing effectiveness	1128:1164	different wound healing effectiveness	1128:1164	The results indicate that BNC biosynthesized by different strains displayed different wound healing effectiveness.					
35287849	7	47	theme	BNC	1196:1198	arg1	membranes					1200:1208	BNC membranes	1196:1208	BNC membranes	1196:1208	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	7	48	theme	upper	1250:1254	arg1	surface					1256:1262	the denser upper surface outward	1239:1270	the denser upper surface outward	1239:1270	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	3	49	theme	lower	638:642	arg1	surfaces					644:651	the lower surfaces	634:651	the lower surfaces	634:651	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	7	50	theme	biomaterial	1327:1337	arg1	requirements					1296:1307	the clinical requirements	1283:1307	the clinical requirements of a wound repair biomaterial	1283:1337	Placing the lower surface of BNC membranes in contact with wounds, with the denser upper surface outward, satisfied the clinical requirements of a wound repair biomaterial.					
35287849	3	51	theme	upper	556:560	arg1	denser					605:610	denser	605:610	denser	605:610	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	3	51	theme	upper	556:560	arg1	surfaces					562:569	the upper surfaces	552:569	the upper surfaces of the BNC membranes	552:590	The results demonstrated that the upper surfaces of the BNC membranes were clearly denser and more compact than the lower surfaces, while all varieties were capable of serving as a physical barrier to the invasion of bacteria.					
35287849	0	52	theme	different	54:62	arg1	strains					74:80	different bacterial strains	54:80	different bacterial strains for healing full-thickness skin defects	54:120	Evaluation of wet nanocellulose membranes produced by different bacterial strains for healing full-thickness skin defects.					
35287849	4	53	theme	BNC	815:817	arg1	membranes					819:827	BNC membranes	815:827	BNC membranes	815:827	The growth of fibroblasts demonstrated that the lower surfaces of BNC membranes exhibited biocompatibility superior to that of the upper surfaces.					
35287849	6	54	theme	different	1128:1136	arg1	effectiveness					1152:1164	different wound healing effectiveness	1128:1164	different wound healing effectiveness	1128:1164	The results indicate that BNC biosynthesized by different strains displayed different wound healing effectiveness.					
37302630	5	0	theme	critical	727:734	arg1	temperature					745:755	the lowest critical solution temperature	716:755	the lowest critical solution temperature in the water	716:768	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	3	1	from	70 °C	432:436	arg1	temperature					406:416	an increase temperature	394:416	an increase temperature from 10 °C to 70 °C	394:436	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	1	2	theme	acrylamide	167:176	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	5	3	theme	solution	736:743	arg1	temperature					745:755	the lowest critical solution temperature	716:755	the lowest critical solution temperature in the water	716:768	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	5	4	from	temperature	745:755	arg1	water					764:768	the water	760:768	the water	760:768	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	5	5	theme	practical	854:862	arg1	use					864:866	the practical use	850:866	the practical use process	850:874	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	5	6	theme	use	864:866	arg1	process					868:874	the practical use process	850:874	the practical use process	850:874	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	8	7	theme	smart	1115:1119	arg1	membrane					1128:1135	The smart gating membrane	1111:1135	The smart gating membrane	1111:1135	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	8	8	theme	multi-stage	1173:1183	arg1	separation					1185:1194	substance multi-stage separation	1163:1194	substance multi-stage separation	1163:1194	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	2	9	theme	shell	273:277	arg1	presence					254:261	The presence	250:261	The presence of PNIPAM shell on cellulose nanofibrils (CNFs)	250:309	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	4	10	theme	gating	607:612	arg1	ratio					614:618	The gating ratio	603:618	The gating ratio of the membrane	603:634	The gating ratio of the membrane can reach 2.47.					
37302630	2	11	theme	PNIPAM	266:271	arg1	shell					273:277	PNIPAM shell	266:277	PNIPAM shell	266:277	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	8	12	theme	selective	1200:1208	arg1	separation					1210:1219	selective separation	1200:1219	selective separation	1200:1219	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	8	13	theme	gating	1121:1126	arg1	membrane					1128:1135	The smart gating membrane	1111:1135	The smart gating membrane	1111:1135	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	8	14	theme	substance	1163:1171	arg1	separation					1185:1194	substance multi-stage separation	1163:1194	substance multi-stage separation	1163:1194	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	1	15	theme	PNIPAM	180:185	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	0	16	theme	smart	2:6	arg1	membrane					29:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane showing selective separation and self-cleaning performance.					
37302630	4	17	theme	membrane	627:634	arg1	ratio					614:618	The gating ratio	603:618	The gating ratio of the membrane	603:634	The gating ratio of the membrane can reach 2.47.					
37302630	1	18	theme	smart	100:104	arg1	membrane					113:120	A smart gating membrane	98:120	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT)	98:234	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	1	19	theme	-grafted	187:194	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	0	20	theme	nanocellulose	15:27	arg1	membrane					29:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane showing selective separation and self-cleaning performance.					
37302630	7	21	theme	water	1019:1023	arg1	permeance					1025:1033	the water permeance	1015:1033	the water permeance	1015:1033	In addition, the water permeance can be restored to 370 L·m-2·h-1·bar-1 by washing the membrane under light.					
37302630	3	22	dep	70 °C	432:436	arg1	to					429:430	to	429:430	to	429:430	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	1	23	theme	gating	106:111	arg1	membrane					113:120	A smart gating membrane	98:120	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT)	98:234	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	3	24	theme	average	449:455	arg1	size					462:465	the average pore size	445:465	the average pore size of the membrane	445:481	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	0	25	theme	gating	8:13	arg1	membrane					29:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane	0:36	A smart gating nanocellulose membrane showing selective separation and self-cleaning performance.					
37302630	5	26	theme	CNT	679:681	arg1	effect					669:674	The photothermal effect	652:674	The photothermal effect of CNT	652:681	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	2	27	theme	cellulose	282:290	arg1	nanofibrils					292:302	cellulose nanofibrils	282:302	cellulose nanofibrils (CNFs)	282:309	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	2	27	theme	cellulose	282:290	arg1	CNFs					305:308	CNFs	305:308	CNFs	305:308	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	2	28	from	presence	254:261	arg1	nanofibrils					292:302	cellulose nanofibrils	282:302	cellulose nanofibrils (CNFs)	282:309	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	2	28	from	presence	254:261	arg1	CNFs					305:308	CNFs	305:308	CNFs	305:308	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	3	29	theme	pore	457:460	arg1	size					462:465	the average pore size	445:465	the average pore size of the membrane	445:481	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	3	30	theme	increase	397:404	arg1	temperature					406:416	an increase temperature	394:416	an increase temperature from 10 °C to 70 °C	394:436	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	5	31	theme	whole	804:808	arg1	phase					816:820	the whole water phase	800:820	the whole water phase	800:820	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	3	32	from	440 L·m-2·h-1·bar-1	558:576	arg1	110 nm					514:519	110 nm	514:519	110 nm	514:519	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	3	32	from	440 L·m-2·h-1·bar-1	558:576	arg1	permeance					543:551	the water permeance	533:551	the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1	533:600	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	1	33	theme	carbon	214:219	arg1	CNT					231:233	CNT	231:233	CNT	231:233	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	1	33	theme	carbon	214:219	arg1	nanotube					221:228	carbon nanotube	214:228	carbon nanotube (CNT)	214:234	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	5	34	theme	water	810:814	arg1	phase					816:820	the whole water phase	800:820	the whole water phase	800:820	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	3	35	theme	water	537:541	arg1	permeance					543:551	the water permeance	533:551	the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1	533:600	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	2	36	theme	composite	321:329	arg1	membrane					331:338	the composite membrane	317:338	the composite membrane with thermal responsiveness	317:366	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	0	37	theme	selective	46:54	arg1	separation					56:65	selective separation	46:65	selective separation	46:65	A smart gating nanocellulose membrane showing selective separation and self-cleaning performance.					
37302630	1	38	theme	N-isopropyl	155:165	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	3	39	theme	membrane	474:481	arg1	size					462:465	the average pore size	445:465	the average pore size of the membrane	445:481	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	5	40	theme	photothermal	656:667	arg1	effect					669:674	The photothermal effect	652:674	The photothermal effect of CNT	652:681	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	2	41	with	membrane	331:338	arg1	responsiveness					353:366	thermal responsiveness	345:366	thermal responsiveness	345:366	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	1	42	theme	thermal-sensitive	131:147	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	1	43	theme	poly	149:152	arg1	nanocellulose					196:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose	131:208	A smart gating membrane based on thermal-sensitive poly (N-isopropyl acrylamide) (PNIPAM)-grafted nanocellulose and carbon nanotube (CNT) was prepared.					
37302630	2	44	attach	presence	254:261	arg1	nanofibrils					292:302	cellulose nanofibrils	282:302	cellulose nanofibrils (CNFs)	282:309	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	2	44	attach	presence	254:261	arg1	CNFs					305:308	CNFs	305:308	CNFs	305:308	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	2	44	attach	presence	254:261	arg2	shell					273:277	PNIPAM shell	266:277	PNIPAM shell	266:277	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
37302630	0	45	theme	self-cleaning	71:83	arg1	performance					85:95	self-cleaning performance	71:95	self-cleaning performance	71:95	A smart gating nanocellulose membrane showing selective separation and self-cleaning performance.					
37302630	8	46	contain	has	1137:1139	arg2	application					1148:1158	a wide application	1141:1158	a wide application	1141:1158	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	8	46	contain	has	1137:1139	arg1	membrane					1128:1135	The smart gating membrane	1111:1135	The smart gating membrane	1111:1135	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	3	47	theme	external	372:379	arg1	stimulation					381:391	external stimulation	372:391	external stimulation	372:391	By external stimulation, an increase temperature from 10 °C to 70 °C allows the average pore size of the membrane to be controlled from 28 nm to 110 nm, as well as the water permeance from 440 L·m-2·h-1·bar-1 to 1088 L·m-2·h-1·bar-1.					
37302630	5	48	theme	lowest	720:725	arg1	temperature					745:755	the lowest critical solution temperature	716:755	the lowest critical solution temperature in the water	716:768	The photothermal effect of CNT rapidly warms up the membrane to the lowest critical solution temperature in the water, avoiding the constraint that the whole water phase cannot be heated throughout the practical use process.					
37302630	8	49	theme	wide	1143:1146	arg1	application					1148:1158	a wide application	1141:1158	a wide application	1141:1158	The smart gating membrane has a wide application in substance multi-stage separation and selective separation, and it can realize self-cleaning.					
37302630	2	50	theme	thermal	345:351	arg1	responsiveness					353:366	thermal responsiveness	345:366	thermal responsiveness	345:366	The presence of PNIPAM shell on cellulose nanofibrils (CNFs) endow the composite membrane with thermal responsiveness.					
35908678	2	0	theme	remarkable	484:493	arg1	increase					495:502	a remarkable increase	482:502	a remarkable increase in their compressive modulus	482:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	1	1	theme	ethanol	357:363	arg1	solutions					391:399	ethanol and sodium alginate (ALG) solutions	357:399	solutions	391:399	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	7	2	theme	MB	1432:1433	arg1	adsorption					1435:1444	MB adsorption	1432:1444	MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents	1432:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	3	3	theme	pseudo-second-order	771:789	arg1	kinetics					802:809	pseudo-second-order adsorption kinetics	771:809	pseudo-second-order adsorption kinetics	771:809	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	2	4	from	33 kPa	572:577	arg1	increase					495:502	a remarkable increase	482:502	a remarkable increase in their compressive modulus	482:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	4	from	33 kPa	572:577	arg1	times					630:634	13/12 times	624:634	13/12 times	624:634	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	4	from	33 kPa	572:577	arg1	strength					546:553	collapse strength	537:553	collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa	537:598	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	3	5	theme	composite	676:684	arg1	aerogels					686:693	the composite aerogels	672:693	the composite aerogels	672:693	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	6	6	theme	pseudo-second-order	1202:1220	arg1	kinetics					1222:1229	pseudo-second-order kinetics	1202:1229	pseudo-second-order kinetics	1202:1229	MB adsorption is best described by the Langmuir isotherm and follows pseudo-second-order kinetics.					
35908678	4	7	dep	methylene	915:923	arg1	i.e.					909:912	i.e.	909:912	i.e.	909:912	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	8	from	dye	904:906	arg1	water					939:943	water	939:943	water	939:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	5	9	theme	solutions	1122:1130	arg1	pH					1096:1097	pH	1096:1097	pH	1096:1097	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	9	theme	solutions	1122:1130	arg1	temperature					1104:1114	temperature	1104:1114	temperature	1104:1114	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	9	theme	solutions	1122:1130	arg1	concentration					1081:1093	the initial concentration	1069:1093	the initial concentration	1069:1093	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	4	10	theme	blue	925:928	arg1	methylene					915:923	methylene blue	915:928	methylene blue (MB)	915:933	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	10	theme	blue	925:928	arg1	MB					931:932	MB	931:932	MB	931:932	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	1	11	theme	sodium	369:374	arg1	solutions					391:399	ethanol and sodium alginate (ALG) solutions	357:399	solutions	391:399	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	6	12	theme	MB	1133:1134	arg1	adsorption					1136:1145	MB adsorption	1133:1145	MB adsorption	1133:1145	MB adsorption is best described by the Langmuir isotherm and follows pseudo-second-order kinetics.					
35908678	1	13	theme	alginate	376:383	arg1	solutions					391:399	ethanol and sodium alginate (ALG) solutions	357:399	solutions	391:399	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	4	14	theme	efficient	860:868	arg1	aerogel					840:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	14	theme	efficient	860:868	arg1	floating					870:877	an efficient floating	857:877	an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water	857:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	2	15	theme	compressive	513:523	arg1	modulus					525:531	their compressive modulus	507:531	their compressive modulus	507:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	7	16	theme	due	1446:1448	arg1	adsorption					1435:1444	MB adsorption	1432:1444	MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents	1432:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	4	17	theme	composite	830:838	arg1	aerogel					840:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	17	theme	composite	830:838	arg1	floating					870:877	an efficient floating	857:877	an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water	857:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	7	18	theme	ALG	1253:1255	arg1	Ca2+-crosslinking					1232:1248	Ca2+-crosslinking	1232:1248	Ca2+-crosslinking of ALG	1232:1255	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	7	19	theme	slow	1399:1402	arg1	step					1423:1426	a slow internal diffusion step	1397:1426	a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents	1397:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	2	20	theme	resulting	406:414	arg1	aerogels					426:433	The resulting composite aerogels	402:433	The resulting composite aerogels	402:433	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	0	21	theme	phase	118:122	arg1	separation					124:133	phase separation	118:133	phase separation as environmental floating adsorbents	118:170	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	1	22	theme	ALG	386:388	arg1	solutions					391:399	ethanol and sodium alginate (ALG) solutions	357:399	solutions	391:399	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	4	23	theme	porous	823:828	arg1	aerogel					840:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	23	theme	porous	823:828	arg1	floating					870:877	an efficient floating	857:877	an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water	857:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	0	24	theme	Alginate-reinforced	0:18	arg1	3-hydroxybutyrate					25:41	Alginate-reinforced poly(3-hydroxybutyrate)	0:42	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate)	0:84	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	0	25	theme	poly	20:23	arg1	3-hydroxybutyrate					25:41	Alginate-reinforced poly(3-hydroxybutyrate)	0:42	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate)	0:84	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	5	26	theme	operating	1040:1048	arg1	pH					1096:1097	pH	1096:1097	pH	1096:1097	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	26	theme	operating	1040:1048	arg1	temperature					1104:1114	temperature	1104:1114	temperature	1104:1114	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	26	theme	operating	1040:1048	arg1	concentration					1081:1093	the initial concentration	1069:1093	the initial concentration	1069:1093	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	26	theme	operating	1040:1048	arg1	parameters					1050:1059	the adsorbent, as well as operating parameters	1014:1059	the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions	1014:1130	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	2	27	theme	52 wt	453:457	arg1	fraction					460:467	a 52 wt% fraction	451:467	a 52 wt% fraction	451:467	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	1	28	theme	nonsolvent	287:296	arg1	separation					312:321	nonsolvent induced phase separation	287:321	nonsolvent induced phase separation	287:321	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	7	29	theme	network	1467:1473	arg1	structure					1475:1483	its tightened network structure	1453:1483	its tightened network structure relative to noncrosslinked adsorbents	1453:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	7	30	theme	MB	1324:1325	arg1	capability					1338:1347	MB adsorption capability	1324:1347	MB adsorption capability	1324:1347	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	7	31	theme	diffusion	1413:1421	arg1	step					1423:1426	a slow internal diffusion step	1397:1426	a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents	1397:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	1	32	theme	induced	298:304	arg1	separation					312:321	nonsolvent induced phase separation	287:321	nonsolvent induced phase separation	287:321	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	0	33	theme	environmental	138:150	arg1	adsorbents					161:170	environmental floating adsorbents	138:170	environmental floating adsorbents	138:170	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	1	34	theme	phase	306:310	arg1	separation					312:321	nonsolvent induced phase separation	287:321	nonsolvent induced phase separation	287:321	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	4	35	dep	dye	904:906	arg1	methylene					915:923	methylene blue	915:928	methylene blue (MB)	915:933	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	35	dep	dye	904:906	arg1	MB					931:932	MB	931:932	MB	931:932	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	3	36	from	contents	660:667	arg1	aerogels					686:693	the composite aerogels	672:693	the composite aerogels	672:693	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	7	37	theme	noncrosslinked	1497:1510	arg1	adsorbents					1512:1521	noncrosslinked adsorbents	1497:1521	noncrosslinked adsorbents	1497:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	7	38	theme	compressive	1275:1285	arg1	strength					1287:1294	compressive strength	1275:1294	compressive strength	1275:1294	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	5	39	theme	initial	1073:1079	arg1	concentration					1081:1093	the initial concentration	1069:1093	the initial concentration	1069:1093	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	0	40	theme	floating	152:159	arg1	adsorbents					161:170	environmental floating adsorbents	138:170	environmental floating adsorbents	138:170	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	5	41	theme	adsorbent	1018:1026	arg1	pH					1096:1097	pH	1096:1097	pH	1096:1097	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	41	theme	adsorbent	1018:1026	arg1	temperature					1104:1114	temperature	1104:1114	temperature	1104:1114	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	41	theme	adsorbent	1018:1026	arg1	concentration					1081:1093	the initial concentration	1069:1093	the initial concentration	1069:1093	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	41	theme	adsorbent	1018:1026	arg1	parameters					1050:1059	the adsorbent, as well as operating parameters	1014:1059	the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions	1014:1130	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	7	42	theme	pseudo-first-order	1359:1376	arg1	kinetics					1378:1385	pseudo-first-order kinetics	1359:1385	pseudo-first-order kinetics	1359:1385	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	2	43	theme	composite	416:424	arg1	aerogels					426:433	The resulting composite aerogels	402:433	The resulting composite aerogels	402:433	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	44	from	increase	495:502	arg1	modulus					525:531	their compressive modulus	507:531	their compressive modulus	507:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	7	45	theme	adsorption	1327:1336	arg1	capability					1338:1347	MB adsorption capability	1324:1347	MB adsorption capability	1324:1347	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	2	46	from	times	630:634	arg1	modulus					525:531	their compressive modulus	507:531	their compressive modulus	507:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	47	theme	collapse	537:544	arg1	strength					546:553	collapse strength	537:553	collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa	537:598	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	4	48	theme	adsorbent	879:887	arg1	aerogel					840:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel	812:846	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	4	48	theme	adsorbent	879:887	arg1	floating					870:877	an efficient floating	857:877	an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water	857:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	6	49	theme	Langmuir	1172:1179	arg1	isotherm					1181:1188	the Langmuir isotherm	1168:1188	the Langmuir isotherm	1168:1188	MB adsorption is best described by the Langmuir isotherm and follows pseudo-second-order kinetics.					
35908678	3	50	theme	soybean	745:751	arg1	oil					753:755	soybean oil	745:755	soybean oil	745:755	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	4	51	theme	cationic	895:902	arg1	dye					904:906	a cationic dye	893:906	a cationic dye (i.e., methylene blue (MB)) in water	893:943	The highly porous composite aerogel acted as an efficient floating adsorbent for a cationic dye (i.e., methylene blue (MB)) in water.					
35908678	3	52	theme	ALG	656:658	arg1	contents					660:667	the ALG contents	652:667	the ALG contents in the composite aerogels	652:693	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	0	53	dep	3-hydroxybutyrate	25:41	arg1	hydroxybutyrate-co-hydroxyvalerate					50:83	hydroxybutyrate-co-hydroxyvalerate	50:83	hydroxybutyrate-co-hydroxyvalerate	50:83	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	0	53	dep	3-hydroxybutyrate	25:41	arg1	poly					45:48	poly	45:48	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate)	0:84	Alginate-reinforced poly(3-hydroxybutyrate)/ poly(hydroxybutyrate-co-hydroxyvalerate) aerogel monoliths fabricated by phase separation as environmental floating adsorbents.					
35908678	2	54	from	strength	546:553	arg1	modulus					525:531	their compressive modulus	507:531	their compressive modulus	507:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	7	55	theme	internal	1404:1411	arg1	step					1423:1426	a slow internal diffusion step	1397:1426	a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents	1397:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	5	56	theme	ALG	998:1000	arg1	contents					1002:1009	ALG contents	998:1009	ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions	998:1130	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	57	theme	MB	946:947	arg1	adsorption					949:958	MB adsorption	946:958	MB adsorption	946:958	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	58	theme	MB	1119:1120	arg1	solutions					1122:1130	MB solutions	1119:1130	MB solutions	1119:1130	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	1	59	theme	Poly	173:176	arg1	monoliths					259:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths	173:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths	173:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
35908678	3	60	theme	adsorption	791:800	arg1	kinetics					802:809	pseudo-second-order adsorption kinetics	771:809	pseudo-second-order adsorption kinetics	771:809	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	3	61	from	increase	640:647	arg1	contents					660:667	the ALG contents	652:667	the ALG contents in the composite aerogels	652:693	An increase in the ALG contents in the composite aerogels allowed them to effectively adsorb both water and soybean oil, according to pseudo-second-order adsorption kinetics.					
35908678	7	62	theme	relative	1485:1492	arg1	structure					1475:1483	its tightened network structure	1453:1483	its tightened network structure relative to noncrosslinked adsorbents	1453:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	7	63	link	noncrosslinked	1497:1510	arg1	adsorbents					1512:1521	noncrosslinked adsorbents	1497:1521	noncrosslinked adsorbents	1497:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	2	64	from	0.3 MPa	560:566	arg1	increase					495:502	a remarkable increase	482:502	a remarkable increase in their compressive modulus	482:531	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	64	from	0.3 MPa	560:566	arg1	times					630:634	13/12 times	624:634	13/12 times	624:634	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	64	from	0.3 MPa	560:566	arg1	strength					546:553	collapse strength	537:553	collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa	537:598	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	5	65	from	contents	1002:1009	arg1	pH					1096:1097	pH	1096:1097	pH	1096:1097	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	65	from	contents	1002:1009	arg1	temperature					1104:1114	temperature	1104:1114	temperature	1104:1114	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	65	from	contents	1002:1009	arg1	concentration					1081:1093	the initial concentration	1069:1093	the initial concentration	1069:1093	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	5	65	from	contents	1002:1009	arg1	parameters					1050:1059	the adsorbent, as well as operating parameters	1014:1059	the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions	1014:1130	MB adsorption was found to be strongly dependent on ALG contents in the adsorbent, as well as operating parameters such as the initial concentration, pH, and temperature of MB solutions.					
35908678	7	66	theme	tightened	1457:1465	arg1	structure					1475:1483	its tightened network structure	1453:1483	its tightened network structure relative to noncrosslinked adsorbents	1453:1521	Ca2+-crosslinking of ALG further increased compressive strength but significantly decreased MB adsorption capability following pseudo-first-order kinetics, implying a slow internal diffusion step for MB adsorption due to its tightened network structure relative to noncrosslinked adsorbents.					
35908678	2	67	theme	%	458:458	arg1	fraction					460:467	a 52 wt% fraction	451:467	a 52 wt% fraction	451:467	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	2	68	dep	times	630:634	arg1	i.e.					615:618	i.e.	615:618	i.e.	615:618	The resulting composite aerogels contained up to a 52 wt% fraction ALG, causing a remarkable increase in their compressive modulus and collapse strength from 0.3 MPa and 33 kPa to 4 MPa and 406 kPa, respectively, i.e., by 13/12 times.					
35908678	1	69	theme	aerogel	251:257	arg1	monoliths					259:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths	173:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths	173:267	Poly(3-hydroxybutyrate) (PHB)/poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) aerogel monoliths were prepared via nonsolvent induced phase separation and then sequentially immersed in ethanol and sodium alginate (ALG) solutions.					
37377346	6	0	theme	porphyrin-based	1274:1288	arg1	COF					1290:1292	the porphyrin-based COF	1270:1292	the porphyrin-based COF	1270:1292	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	2	1	with	cellulose	618:626	arg1	structures					677:686	their unique structures	664:686	their unique structures	664:686	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	2	1	with	cellulose	618:626	arg1	forces					709:714	hydrogen bonding forces	692:714	hydrogen bonding forces	692:714	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	3	2	theme	composite	748:756	arg1	membrane					758:765	this composite membrane	743:765	this composite membrane toward methyl green and congo red	743:799	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	1	3	theme	application	196:206	arg1	prospect					208:215	a wide application prospect	189:215	a wide application prospect	189:215	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	4	theme	BC/COF	1440:1445	arg1	membrane					1457:1464	The self-supporting BC/COF composite membrane	1420:1464	The self-supporting BC/COF composite membrane synthesized by this strategy	1420:1493	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	2	5	theme	porphyrin-based	639:653	arg1	COF					655:657	a porphyrin-based COF	637:657	a porphyrin-based COF with their unique structures and hydrogen bonding forces	637:714	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	5	6	dep	hydrophilicity	1001:1014	arg1	the					997:999	the	997:999	the	997:999	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	7	7	theme	materials	1652:1660	arg1	application					1633:1643	the application	1629:1643	the application of COF materials in water treatment	1629:1679	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	4	8	theme	pH	911:912	arg1	conditions					914:923	different pH conditions	901:923	different pH conditions	901:923	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	5	9	theme	membrane	1063:1070	arg1	hydrophilicity					1001:1014	hydrophilicity	1001:1014	hydrophilicity	1001:1014	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	5	9	theme	membrane	1063:1070	arg1	negativity					1028:1037	surface negativity	1020:1037	surface negativity	1020:1037	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	1	10	theme	COF	418:420	arg1	powders					422:428	COF powders	418:428	COF powders formed at high temperature and high pressure	418:473	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	4	11	theme	excellent	875:883	arg1	stability					885:893	excellent stability	875:893	excellent stability	875:893	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	6	12	theme	excellent	1214:1222	arg1	properties					1238:1247	excellent antibacterial properties	1214:1247	excellent antibacterial properties	1214:1247	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	1	13	theme	organic	158:164	arg1	frameworks					166:175	Covalent organic frameworks	149:175	Covalent organic frameworks (COFs)	149:182	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	13	theme	organic	158:164	arg1	COFs					178:181	COFs	178:181	COFs	178:181	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	3	14	theme	L	848:848	arg1	bar-1					858:862	about 195 L m-2 h-1 bar-1	838:862	about 195 L m-2 h-1 bar-1	838:862	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	14	theme	L	848:848	arg1	permeance					824:832	the permeance	820:832	the permeance	820:832	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	5	15	theme	BC/COF	1046:1051	arg1	membrane					1063:1070	the BC/COF composite membrane	1042:1070	the BC/COF composite membrane	1042:1070	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	4	16	theme	experimental	959:970	arg1	conditions					972:981	cyclic experimental conditions	952:981	cyclic experimental conditions	952:981	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	0	17	theme	Antifouling	88:98	arg1	Properties					118:127	Antifouling and Antibacterial Properties	88:127	Antifouling and Antibacterial Properties for Dye Separation	88:146	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	1	18	theme	great	348:352	arg1	challenge					354:362	a great challenge	346:362	a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure	346:473	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	6	19	theme	visible	1405:1411	arg1	light					1413:1417	visible light	1405:1417	visible light	1405:1417	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	7	20	theme	separation	1587:1596	arg1	effects					1598:1604	excellent dye separation effects	1573:1604	excellent dye separation effects	1573:1604	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	2	21	theme	continuous	493:502	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	0	22	theme	Antibacterial	104:116	arg1	Properties					118:127	Antifouling and Antibacterial Properties	88:127	Antifouling and Antibacterial Properties for Dye Separation	88:146	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	5	23	theme	flux	1126:1129	arg1	rate					1140:1143	the flux recovery rate	1122:1143	the flux recovery rate	1122:1143	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	1	24	theme	high	440:443	arg1	temperature					445:455	high temperature	440:455	high temperature	440:455	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	3	25	theme	h-1	854:856	arg1	bar-1					858:862	about 195 L m-2 h-1 bar-1	838:862	about 195 L m-2 h-1 bar-1	838:862	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	25	theme	h-1	854:856	arg1	permeance					824:832	the permeance	820:832	the permeance	820:832	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	7	26	theme	excellent	1573:1581	arg1	effects					1598:1604	excellent dye separation effects	1573:1604	excellent dye separation effects	1573:1604	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	2	27	theme	framework	557:565	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	5	28	theme	certain	1085:1091	arg1	performance					1105:1115	certain antifouling performance	1085:1115	certain antifouling performance	1085:1115	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	2	29	theme	cellulose/covalent	530:547	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	6	30	theme	coli	1338:1341	arg1	%					1385:1385	less than 1%	1374:1385	less than 1%	1374:1385	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	6	30	theme	coli	1338:1341	arg1	rates					1312:1316	the survival rates	1299:1316	the survival rates of both Escherichia coli and Staphylococcus aureus	1299:1367	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	1	31	theme	insolubility	381:392	arg1	reason					367:372	reason	367:372	reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure	367:473	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	2	32	theme	defect-free	508:518	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	3	33	theme	membrane	758:765	arg1	%					813:813	up to 99%	805:813	up to 99%	805:813	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	33	theme	membrane	758:765	arg1	rate					735:738	The dye rejection rate	717:738	The dye rejection rate of this composite membrane toward methyl green and congo red	717:799	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	0	34	theme	Multifunctional	0:14	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	2	35	theme	hydrogen	692:699	arg1	bonding					701:707	hydrogen bonding	692:707	hydrogen bonding forces	692:714	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	0	36	theme	Cellulose/Covalent	26:43	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	0	37	theme	Framework	53:61	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	1	38	theme	COF	324:326	arg1	membranes					328:336	pure COF membranes	319:336	pure COF membranes	319:336	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	39	theme	outstanding	1504:1514	arg1	properties					1546:1555	outstanding antifouling and antibacterial properties	1504:1555	outstanding antifouling and antibacterial properties	1504:1555	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	0	40	with	Membranes	73:81	arg1	Properties					118:127	Antifouling and Antibacterial Properties	88:127	Antifouling and Antibacterial Properties for Dye Separation	88:146	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	6	41	theme	COF	1290:1292	arg1	doping					1260:1265	the doping	1256:1265	the doping of the porphyrin-based COF	1256:1292	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	3	42	theme	dye	721:723	arg1	%					813:813	up to 99%	805:813	up to 99%	805:813	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	42	theme	dye	721:723	arg1	rate					735:738	The dye rejection rate	717:738	The dye rejection rate of this composite membrane toward methyl green and congo red	717:799	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	1	43	theme	high	461:464	arg1	pressure					466:473	high pressure	461:473	high pressure	461:473	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	44	theme	composite	1447:1455	arg1	membrane					1457:1464	The self-supporting BC/COF composite membrane	1420:1464	The self-supporting BC/COF composite membrane synthesized by this strategy	1420:1493	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	1	45	contain	have	184:187	arg1	frameworks					166:175	Covalent organic frameworks	149:175	Covalent organic frameworks (COFs)	149:182	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	45	contain	have	184:187	arg1	COFs					178:181	COFs	178:181	COFs	178:181	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	45	contain	have	184:187	arg2	prospect					208:215	a wide application prospect	189:215	a wide application prospect	189:215	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	46	theme	wide	191:194	arg1	prospect					208:215	a wide application prospect	189:215	a wide application prospect	189:215	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	47	theme	self-supporting	1424:1438	arg1	membrane					1457:1464	The self-supporting BC/COF composite membrane	1420:1464	The self-supporting BC/COF composite membrane synthesized by this strategy	1420:1493	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	7	48	theme	COF	1648:1650	arg1	materials					1652:1660	COF materials	1648:1660	COF materials	1648:1660	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	1	49	theme	wastewater	220:229	arg1	treatment					231:239	wastewater treatment	220:239	wastewater treatment	220:239	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	4	50	theme	different	901:909	arg1	conditions					914:923	different pH conditions	901:923	different pH conditions	901:923	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	3	51	theme	methyl	774:779	arg1	green					781:785	methyl green	774:785	methyl green	774:785	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	52	dep	99	811:812	arg1	to					808:809	to	808:809	to	808:809	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	2	53	with	COF	655:657	arg1	structures					677:686	their unique structures	664:686	their unique structures	664:686	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	2	53	with	COF	655:657	arg1	forces					709:714	hydrogen bonding forces	692:714	hydrogen bonding forces	692:714	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	2	54	theme	composite	567:575	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	6	55	theme	antibacterial	1224:1236	arg1	properties					1238:1247	excellent antibacterial properties	1214:1247	excellent antibacterial properties	1214:1247	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	6	56	theme	aureus	1362:1367	arg1	%					1385:1385	less than 1%	1374:1385	less than 1%	1374:1385	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	6	56	theme	aureus	1362:1367	arg1	rates					1312:1316	the survival rates	1299:1316	the survival rates of both Escherichia coli and Staphylococcus aureus	1299:1367	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	6	57	theme	survival	1303:1310	arg1	%					1385:1385	less than 1%	1374:1385	less than 1%	1374:1385	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	6	57	theme	survival	1303:1310	arg1	rates					1312:1316	the survival rates	1299:1316	the survival rates of both Escherichia coli and Staphylococcus aureus	1299:1367	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	1	58	theme	powders	422:428	arg1	unprocessability					398:413	unprocessability	398:413	unprocessability	398:413	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	58	theme	powders	422:428	arg1	insolubility					381:392	insolubility	381:392	insolubility	381:392	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	59	theme	Covalent	149:156	arg1	frameworks					166:175	Covalent organic frameworks	149:175	Covalent organic frameworks (COFs)	149:182	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	59	theme	Covalent	149:156	arg1	COFs					178:181	COFs	178:181	COFs	178:181	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	2	60	theme	bacterial	608:616	arg1	BC					629:630	BC	629:630	BC	629:630	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	2	60	theme	bacterial	608:616	arg1	cellulose					618:626	bacterial cellulose	608:626	bacterial cellulose (BC)	608:631	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	3	61	theme	m-2	850:852	arg1	bar-1					858:862	about 195 L m-2 h-1 bar-1	838:862	about 195 L m-2 h-1 bar-1	838:862	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	61	theme	m-2	850:852	arg1	permeance					824:832	the permeance	820:832	the permeance	820:832	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	7	62	contain	has	1500:1502	arg1	membrane					1457:1464	The self-supporting BC/COF composite membrane	1420:1464	The self-supporting BC/COF composite membrane synthesized by this strategy	1420:1493	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	7	62	contain	has	1500:1502	arg2	properties					1546:1555	outstanding antifouling and antibacterial properties	1504:1555	outstanding antifouling and antibacterial properties	1504:1555	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	6	63	theme	composite	1185:1193	arg1	membrane					1195:1202	the composite membrane	1181:1202	the composite membrane	1181:1202	More importantly, the composite membrane exhibited excellent antibacterial properties due to the doping of the porphyrin-based COF, and the survival rates of both Escherichia coli and Staphylococcus aureus were less than 1% after exposure to visible light.					
37377346	5	64	theme	composite	1053:1061	arg1	membrane					1063:1070	the BC/COF composite membrane	1042:1070	the BC/COF composite membrane	1042:1070	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	7	65	theme	dye	1583:1585	arg1	effects					1598:1604	excellent dye separation effects	1573:1604	excellent dye separation effects	1573:1604	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	4	66	theme	cyclic	952:957	arg1	conditions					972:981	cyclic experimental conditions	952:981	cyclic experimental conditions	952:981	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	4	67	theme	long-time	926:934	arg1	filtration					936:945	long-time filtration	926:945	long-time filtration	926:945	It showed excellent stability under different pH conditions, long-time filtration, and cyclic experimental conditions.					
37377346	1	68	theme	unprocessability	398:413	arg1	reason					367:372	reason	367:372	reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure	367:473	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	0	69	theme	Dye	133:135	arg1	Separation					137:146	Dye Separation	133:146	Dye Separation	133:146	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	5	70	theme	recovery	1131:1138	arg1	rate					1140:1143	the flux recovery rate	1122:1143	the flux recovery rate	1122:1143	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	2	71	theme	organic	549:555	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	2	72	theme	unique	670:675	arg1	structures					677:686	their unique structures	664:686	their unique structures	664:686	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	5	73	theme	antifouling	1093:1103	arg1	performance					1105:1115	certain antifouling performance	1085:1115	certain antifouling performance	1085:1115	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	7	74	from	application	1633:1643	arg1	treatment					1671:1679	water treatment	1665:1679	water treatment	1665:1679	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	2	75	theme	bacterial	520:528	arg1	membrane					577:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane	491:584	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	0	76	theme	Bacterial	16:24	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	2	77	theme	bonding	701:707	arg1	forces					709:714	hydrogen bonding forces	692:714	hydrogen bonding forces	692:714	In this study, a continuous and defect-free bacterial cellulose/covalent organic framework composite membrane was prepared by using bacterial cellulose (BC) and a porphyrin-based COF with their unique structures and hydrogen bonding forces.					
37377346	0	78	theme	Organic	45:51	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	0	79	theme	Composite	63:71	arg1	Membranes					73:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes	0:81	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.	0:147	Multifunctional Bacterial Cellulose/Covalent Organic Framework Composite Membranes with Antifouling and Antibacterial Properties for Dye Separation.					
37377346	1	80	theme	pure	319:322	arg1	membranes					328:336	pure COF membranes	319:336	pure COF membranes	319:336	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	81	theme	water	1665:1669	arg1	treatment					1671:1679	water treatment	1665:1679	water treatment	1665:1679	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	1	82	dep	insolubility	381:392	arg1	the					377:379	the	377:379	the	377:379	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	1	83	theme	membranes	328:336	arg1	preparation					304:314	the preparation	300:314	the preparation of pure COF membranes	300:336	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	7	84	theme	antibacterial	1532:1544	arg1	properties					1546:1555	outstanding antifouling and antibacterial properties	1504:1555	outstanding antifouling and antibacterial properties	1504:1555	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	5	85	theme	surface	1020:1026	arg1	negativity					1028:1037	surface negativity	1020:1037	surface negativity	1020:1037	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	7	86	dep	effects	1598:1604	arg1	addition					1561:1568	addition	1561:1568	addition	1561:1568	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	7	87	theme	antifouling	1516:1526	arg1	properties					1546:1555	outstanding antifouling and antibacterial properties	1504:1555	outstanding antifouling and antibacterial properties	1504:1555	The self-supporting BC/COF composite membrane synthesized by this strategy also has outstanding antifouling and antibacterial properties, in addition to excellent dye separation effects, which greatly broaden the application of COF materials in water treatment.					
37377346	5	88	dep	it	1077:1078	arg1	have					1080:1083	have	1080:1083	have certain antifouling performance	1080:1115	In addition, the hydrophilicity and surface negativity of the BC/COF composite membrane made it have certain antifouling performance, and the flux recovery rate can reach 93.72%.					
37377346	1	89	theme	unique	258:263	arg1	structure					265:273	their unique structure	252:273	their unique structure	252:273	Covalent organic frameworks (COFs) have a wide application prospect in wastewater treatment because of their unique structure and properties; however, the preparation of pure COF membranes remains a great challenge by reason of the insolubility and unprocessability of COF powders formed at high temperature and high pressure.					
37377346	3	90	theme	rejection	725:733	arg1	%					813:813	up to 99%	805:813	up to 99%	805:813	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
37377346	3	90	theme	rejection	725:733	arg1	rate					735:738	The dye rejection rate	717:738	The dye rejection rate of this composite membrane toward methyl green and congo red	717:799	The dye rejection rate of this composite membrane toward methyl green and congo red was up to 99%, and the permeance was about 195 L m-2 h-1 bar-1.					
36808125	0	0	theme	transmission-blocking	82:102	arg1	vaccine					117:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	4	1	theme	eukaryotic	681:690	arg1	systems					692:698	eukaryotic systems	681:698	eukaryotic systems	681:698	For example, to date, a non-native N-glycan is required to stabilize the domain when produced in eukaryotic systems.					
36808125	6	2	theme	self-assembling	1015:1029	arg1	nanoparticle					1048:1059	a self-assembling single-component nanoparticle	1013:1059	a self-assembling single-component nanoparticle	1013:1059	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	0	3	theme	malaria	74:80	arg1	vaccine					117:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	5	4	with	antigen	909:915	arg1	characteristics					931:945	improved characteristics	922:945	improved characteristics for vaccine manufacture	922:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	2	5	from	antigen	338:344	arg1	development					349:359	development	349:359	development	349:359	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	1	6	from	human	183:187	arg1	transmission					165:176	parasite transmission	156:176	parasite transmission from human to mosquito	156:199	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	5	7	theme	Pfs48/45	897:904	arg1	antigen					909:915	a stabilized non-glycosylated Pfs48/45 D3 antigen	867:915	a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture	867:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	0	8	theme	nanoparticle	104:115	arg1	vaccine					117:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	4	9	theme	non-native	608:617	arg1	N-glycan					619:626	a non-native N-glycan	606:626	a non-native N-glycan	606:626	For example, to date, a non-native N-glycan is required to stabilize the domain when produced in eukaryotic systems.					
36808125	6	10	from	doses	1154:1158	arg1	activity					1127:1134	potent transmission-reducing activity	1098:1134	potent transmission-reducing activity in rodents at low doses	1098:1158	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	6	11	from	activity	1127:1134	arg1	rodents					1139:1145	rodents	1139:1145	rodents	1139:1145	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	3	12	theme	production	535:544	arg1	challenges					546:555	production challenges	535:555	production challenges	535:555	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	5	13	theme	in	758:759	arg1	pipeline					777:784	in vitro screening pipeline	758:784	in vitro screening pipeline	758:784	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	1	14	theme	powerful	212:219	arg1	method					221:226	a powerful method	210:226	a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans	210:311	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	1	14	theme	powerful	212:219	arg1	vaccine					136:142	A malaria vaccine	126:142	A malaria vaccine that blocks parasite transmission from human to mosquito	126:199	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	5	15	theme	SPEEDesign	722:731	arg1	design					747:752	a SPEEDesign computational design	720:752	a SPEEDesign computational design	720:752	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	2	16	dep	parasite	432:439	arg1	falciparum					452:461	Plasmodium falciparum	441:461	the deadliest malaria parasite Plasmodium falciparum	410:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	7	17	theme	antigens	1342:1349	arg1	design					1318:1323	the design	1314:1323	the design of other vaccine antigens and therapeutics without interfering glycans	1314:1394	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	5	18	theme	D3	906:907	arg1	antigen					909:915	a stabilized non-glycosylated Pfs48/45 D3 antigen	867:915	a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture	867:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	6	19	theme	transmission-reducing	1105:1125	arg1	activity					1127:1134	potent transmission-reducing activity	1098:1134	potent transmission-reducing activity in rodents at low doses	1098:1158	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	7	20	theme	powerful	1212:1219	arg1	approaches					1221:1230	many new and powerful approaches	1199:1230	many new and powerful approaches to TBV development	1199:1249	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	3	21	theme	TBV	516:518	arg1	candidate					520:528	an established TBV candidate	501:528	an established TBV candidate	501:528	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	21	theme	TBV	516:518	arg1	domain					474:479	The third domain	464:479	The third domain of Pfs48/45 (D3)	464:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	21	theme	TBV	516:518	arg1	Pfs48/45					484:491	Pfs48/45	484:491	Pfs48/45 (D3)	484:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	5	22	theme	computational	733:745	arg1	design					747:752	a SPEEDesign computational design	720:752	a SPEEDesign computational design	720:752	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	5	23	theme	vaccine	951:957	arg1	manufacture					959:969	vaccine manufacture	951:969	vaccine manufacture	951:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	3	24	theme	established	504:514	arg1	candidate					520:528	an established TBV candidate	501:528	an established TBV candidate	501:528	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	24	theme	established	504:514	arg1	domain					474:479	The third domain	464:479	The third domain of Pfs48/45 (D3)	464:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	24	theme	established	504:514	arg1	Pfs48/45					484:491	Pfs48/45	484:491	Pfs48/45 (D3)	484:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	6	25	theme	potent	1098:1103	arg1	activity					1127:1134	potent transmission-reducing activity	1098:1134	potent transmission-reducing activity in rodents at low doses	1098:1158	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	7	26	theme	many	1199:1202	arg1	approaches					1221:1230	many new and powerful approaches	1199:1230	many new and powerful approaches to TBV development	1199:1249	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	5	27	theme	stabilized	869:878	arg1	antigen					909:915	a stabilized non-glycosylated Pfs48/45 D3 antigen	867:915	a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture	867:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	2	28	theme	Plasmodium	441:450	arg1	falciparum					452:461	Plasmodium falciparum	441:461	the deadliest malaria parasite Plasmodium falciparum	410:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	1	29	theme	disease	295:301	arg1	incidence					282:290	the incidence	278:290	the incidence of disease in humans	278:311	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	2	30	theme	malaria	424:430	arg1	parasite					432:439	the deadliest malaria parasite Plasmodium falciparum	410:461	the deadliest malaria parasite Plasmodium falciparum	410:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	5	31	theme	transmission	810:821	arg1	epitope					832:838	the potent transmission blocking epitope	799:838	the potent transmission blocking epitope in Pfs48/45	799:850	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	1	32	from	incidence	282:290	arg1	humans					306:311	humans	306:311	humans	306:311	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	5	33	theme	potent	803:808	arg1	epitope					832:838	the potent transmission blocking epitope	799:838	the potent transmission blocking epitope in Pfs48/45	799:850	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	2	34	theme	deadliest	414:422	arg1	parasite					432:439	the deadliest malaria parasite Plasmodium falciparum	410:461	the deadliest malaria parasite Plasmodium falciparum	410:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	0	35	theme	Pfs48/45	40:47	arg1	antigen					49:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	5	36	dep	in	758:759	arg1	vitro					761:765	vitro	761:765	vitro	761:765	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	7	37	theme	TBV	1235:1237	arg1	development					1239:1249	TBV development	1235:1249	TBV development	1235:1249	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	7	38	theme	therapeutics	1355:1366	arg1	design					1318:1323	the design	1314:1323	the design of other vaccine antigens and therapeutics without interfering glycans	1314:1394	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	0	39	theme	non-glycosylated	23:38	arg1	antigen					49:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	5	40	theme	screening	767:775	arg1	pipeline					777:784	in vitro screening pipeline	758:784	in vitro screening pipeline	758:784	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	0	41	theme	stabilized	12:21	arg1	antigen					49:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	3	42	theme	third	468:472	arg1	candidate					520:528	an established TBV candidate	501:528	an established TBV candidate	501:528	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	42	theme	third	468:472	arg1	domain					474:479	The third domain	464:479	The third domain of Pfs48/45 (D3)	464:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	42	theme	third	468:472	arg1	Pfs48/45					484:491	Pfs48/45	484:491	Pfs48/45 (D3)	484:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	7	43	theme	Pfs48/45	1174:1181	arg1	antigen					1183:1189	The enhanced Pfs48/45 antigen	1161:1189	The enhanced Pfs48/45 antigen	1161:1189	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	5	44	theme	non-glycosylated	880:895	arg1	antigen					909:915	a stabilized non-glycosylated Pfs48/45 D3 antigen	867:915	a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture	867:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	7	45	theme	antigen	1261:1267	arg1	method					1276:1281	this antigen design method	1256:1281	this antigen design method	1256:1281	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	6	46	theme	low	1150:1152	arg1	doses					1154:1158	low doses	1150:1158	low doses	1150:1158	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
36808125	1	47	theme	malaria	128:134	arg1	method					221:226	a powerful method	210:226	a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans	210:311	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	1	47	theme	malaria	128:134	arg1	vaccine					136:142	A malaria vaccine	126:142	A malaria vaccine that blocks parasite transmission from human to mosquito	126:199	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	0	48	theme	antigen	49:55	arg1	Design					0:5	Design	0:5	Design of a stabilized non-glycosylated Pfs48/45 antigen	0:55	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	5	49	gly	non-glycosylated	880:895	arg1	antigen					909:915	a stabilized non-glycosylated Pfs48/45 D3 antigen	867:915	a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture	867:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	7	50	theme	enhanced	1165:1172	arg1	antigen					1183:1189	The enhanced Pfs48/45 antigen	1161:1189	The enhanced Pfs48/45 antigen	1161:1189	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	7	51	theme	interfering	1376:1386	arg1	glycans					1388:1394	interfering glycans	1376:1394	interfering glycans	1376:1394	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	5	52	theme	improved	922:929	arg1	characteristics					931:945	improved characteristics	922:945	improved characteristics for vaccine manufacture	922:969	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	7	53	theme	new	1204:1206	arg1	approaches					1221:1230	many new and powerful approaches	1199:1230	many new and powerful approaches to TBV development	1199:1249	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	1	54	theme	parasite	156:163	arg1	transmission					165:176	parasite transmission	156:176	parasite transmission from human to mosquito	156:199	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	0	55	gly	non-glycosylated	23:38	arg1	antigen					49:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	a stabilized non-glycosylated Pfs48/45 antigen	10:55	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	5	56	from	epitope	832:838	arg1	Pfs48/45					843:850	Pfs48/45	843:850	Pfs48/45	843:850	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	3	57	theme	Pfs48/45	484:491	arg1	candidate					520:528	an established TBV candidate	501:528	an established TBV candidate	501:528	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	57	theme	Pfs48/45	484:491	arg1	domain					474:479	The third domain	464:479	The third domain of Pfs48/45 (D3)	464:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	3	57	theme	Pfs48/45	484:491	arg1	Pfs48/45					484:491	Pfs48/45	484:491	Pfs48/45 (D3)	484:496	The third domain of Pfs48/45 (D3) is an established TBV candidate, but production challenges have hampered development.					
36808125	2	58	theme	promising	328:336	arg1	Pfs48/45					314:321	Pfs48/45	314:321	Pfs48/45	314:321	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	2	58	theme	promising	328:336	arg1	antigen					338:344	a promising antigen	326:344	a promising antigen in development	326:359	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	0	59	theme	potent	67:72	arg1	vaccine					117:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	a potent malaria transmission-blocking nanoparticle vaccine	65:123	Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine.					
36808125	7	60	theme	other	1328:1332	arg1	antigens					1342:1349	other vaccine antigens	1328:1349	other vaccine antigens	1328:1349	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	5	61	theme	blocking	823:830	arg1	epitope					832:838	the potent transmission blocking epitope	799:838	the potent transmission blocking epitope in Pfs48/45	799:850	Here, we implement a SPEEDesign computational design and in vitro screening pipeline that retains the potent transmission blocking epitope in Pfs48/45 while creating a stabilized non-glycosylated Pfs48/45 D3 antigen with improved characteristics for vaccine manufacture.					
36808125	2	62	theme	blocking	379:386	arg1	TBV					397:399	TBV	397:399	TBV	397:399	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	2	62	theme	blocking	379:386	arg1	vaccine					388:394	a transmission blocking vaccine	364:394	a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum	364:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	7	63	theme	vaccine	1334:1340	arg1	antigens					1342:1349	other vaccine antigens	1328:1349	other vaccine antigens	1328:1349	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	1	64	theme	parasite	246:253	arg1	lifecycle					255:263	the parasite lifecycle	242:263	the parasite lifecycle	242:263	A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans.					
36808125	7	65	theme	design	1269:1274	arg1	method					1276:1281	this antigen design method	1256:1281	this antigen design method	1256:1281	The enhanced Pfs48/45 antigen enables many new and powerful approaches to TBV development, and this antigen design method can be broadly applied towards the design of other vaccine antigens and therapeutics without interfering glycans.					
36808125	2	66	theme	transmission	366:377	arg1	TBV					397:399	TBV	397:399	TBV	397:399	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	2	66	theme	transmission	366:377	arg1	vaccine					388:394	a transmission blocking vaccine	364:394	a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum	364:461	Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest malaria parasite Plasmodium falciparum.					
36808125	6	67	theme	single-component	1031:1046	arg1	nanoparticle					1048:1059	a self-assembling single-component nanoparticle	1013:1059	a self-assembling single-component nanoparticle	1013:1059	This antigen can be genetically fused to a self-assembling single-component nanoparticle, resulting in a vaccine that elicits potent transmission-reducing activity in rodents at low doses.					
35891601	4	0	theme	MeHA	667:670	arg1	patches					672:678	MeHA patches	667:678	MeHA patches	667:678	MeHA patches were realized by 3D bioprinting technique and they were loaded with hMSC-EXOs.					
35891601	1	1	theme	care	161:164	arg1	management					166:175	Wound care management	155:175	Wound care management	155:175	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	6	2	theme	specific	1040:1047	arg1	markers					1049:1055	specific markers	1040:1055	specific markers related to wound healing process in human fibroblasts and human endothelial cells	1040:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	3	3	theme	healing	649:655	arg1	purposes					657:664	wound healing purposes	643:664	wound healing purposes	643:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	6	4	theme	healing	1074:1080	arg1	process					1082:1088	wound healing process	1068:1088	wound healing process in human fibroblasts and human endothelial cells	1068:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	0	5	theme	regenerative	98:109	arg1	properties					111:120	the regenerative properties	94:120	the regenerative properties of endothelial and dermal cells	94:152	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	3	6	theme	mesenchymal	595:605	arg1	hMSC-EXOs					619:627	hMSC-EXOs	619:627	hMSC-EXOs	619:627	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	6	theme	mesenchymal	595:605	arg1	cells					612:616	human mesenchymal stem cells	589:616	human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	589:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	5	7	theme	degradation	866:876	arg1	time					878:881	extended degradation time	857:881	extended degradation time	857:881	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	2	8	dep	three-dimensional	341:357	arg1	3D					360:361	3D	360:361	3D	360:361	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
35891601	3	9	theme	advanced	520:527	arg1	patches					535:541	advanced smart patches	520:541	advanced smart patches	520:541	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	5	10	theme	mechanical	805:814	arg1	performance					816:826	improved mechanical performance	796:826	improved mechanical performance	796:826	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	3	11	theme	hyaluronic	456:465	arg1	MeHA					473:476	MeHA	473:476	MeHA	473:476	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	11	theme	hyaluronic	456:465	arg1	acid					467:470	hyaluronic acid	456:470	a methacrylated hyaluronic acid (MeHA) bioink	440:484	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	5	12	theme	appropriate	829:839	arg1	ratio					850:854	appropriate swelling ratio	829:854	appropriate swelling ratio	829:854	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	3	13	theme	present	427:433	arg1	work					435:438	the present work	423:438	the present work	423:438	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	5	14	theme	printed	766:772	arg1	patches					779:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	6	15	theme	wound	1068:1072	arg1	healing					1074:1080	wound healing	1068:1080	wound healing process in human fibroblasts and human endothelial cells	1068:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	4	16	theme	bioprinting	700:710	arg1	technique					712:720	3D bioprinting technique	697:720	3D bioprinting technique	697:720	MeHA patches were realized by 3D bioprinting technique and they were loaded with hMSC-EXOs.					
35891601	6	17	theme	related	1057:1063	arg1	markers					1049:1055	specific markers	1040:1055	specific markers related to wound healing process in human fibroblasts and human endothelial cells	1040:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	5	18	theme	MeHA	774:777	arg1	patches					779:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	3	19	theme	patches	535:541	arg1	fabrication					505:515	the fabrication	501:515	the fabrication of advanced smart patches	501:541	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	4	20	theme	3D	697:698	arg1	technique					712:720	3D bioprinting technique	697:720	3D bioprinting technique	697:720	MeHA patches were realized by 3D bioprinting technique and they were loaded with hMSC-EXOs.					
35891601	6	21	theme	markers	1049:1055	arg1	migration					991:999	migration	991:999	migration	991:999	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	6	21	theme	markers	1049:1055	arg1	ability					1013:1019	angiogenic ability	1002:1019	angiogenic ability	1002:1019	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	6	21	theme	markers	1049:1055	arg1	proliferation					976:988	proliferation	976:988	proliferation	976:988	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	6	21	theme	markers	1049:1055	arg1	expression					1026:1035	expression	1026:1035	expression	1026:1035	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	0	22	theme	stem	24:27	arg1	cells					29:33	mesenchymal stem cells	12:33	mesenchymal stem cells delivered from methacrylated hyaluronic acid	12:78	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	2	23	theme	medication	312:321	arg1	use					292:294	the use	288:294	the use of personalized medication	288:321	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
35891601	3	24	theme	methacrylated	442:454	arg1	system					557:562	a delivery system	546:562	a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	546:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	24	theme	methacrylated	442:454	arg1	bioink					479:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	0	25	theme	mesenchymal	12:22	arg1	cells					29:33	mesenchymal stem cells	12:33	mesenchymal stem cells delivered from methacrylated hyaluronic acid	12:78	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	0	26	theme	endothelial	125:135	arg1	cells					148:152	endothelial and dermal cells	125:152	cells	148:152	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	2	27	theme	personalized	299:310	arg1	medication					312:321	personalized medication	299:321	personalized medication	299:321	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
35891601	1	28	theme	innovative	211:220	arg1	dressings					234:242	innovative smart wound dressings	211:242	innovative smart wound dressings	211:242	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	5	29	theme	suitable	888:895	arg1	biocompatibility					897:912	suitable biocompatibility	888:912	suitable biocompatibility	888:912	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	0	30	theme	cells	148:152	arg1	properties					111:120	the regenerative properties	94:120	the regenerative properties of endothelial and dermal cells	94:152	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	6	31	theme	human	1115:1119	arg1	cells					1133:1137	human endothelial cells	1115:1137	human endothelial cells	1115:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	1	32	theme	smart	222:226	arg1	dressings					234:242	innovative smart wound dressings	211:242	innovative smart wound dressings	211:242	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	0	33	theme	cells	29:33	arg1	Exosomes					0:7	Exosomes	0:7	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid	0:78	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	5	34	theme	swelling	841:848	arg1	ratio					850:854	appropriate swelling ratio	829:854	appropriate swelling ratio	829:854	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	0	35	theme	dermal	141:146	arg1	cells					148:152	endothelial and dermal cells	125:152	cells	148:152	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	3	36	theme	stem	607:610	arg1	hMSC-EXOs					619:627	hMSC-EXOs	619:627	hMSC-EXOs	619:627	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	36	theme	stem	607:610	arg1	cells					612:616	human mesenchymal stem cells	589:616	human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	589:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	37	theme	exosomes	567:574	arg1	system					557:562	a delivery system	546:562	a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	546:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	37	theme	exosomes	567:574	arg1	bioink					479:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	1	38	theme	wound	228:232	arg1	dressings					234:242	innovative smart wound dressings	211:242	innovative smart wound dressings	211:242	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	0	39	theme	methacrylated	50:62	arg1	acid					75:78	methacrylated hyaluronic acid	50:78	methacrylated hyaluronic acid	50:78	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	6	40	theme	MeHA	928:931	arg1	patches					933:939	MeHA patches	928:939	MeHA patches loaded with hMSC-EXOs	928:961	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	3	41	theme	delivery	548:555	arg1	system					557:562	a delivery system	546:562	a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	546:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	41	theme	delivery	548:555	arg1	bioink					479:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	6	42	theme	human	1093:1097	arg1	fibroblasts					1099:1109	human fibroblasts	1093:1109	human fibroblasts	1093:1109	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	6	43	theme	endothelial	1121:1131	arg1	cells					1133:1137	human endothelial cells	1115:1137	human endothelial cells	1115:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	5	44	theme	3D	763:764	arg1	patches					779:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches	759:785	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	2	45	theme	three-dimensional	341:357	arg1	bioprinting					364:374	three-dimensional (3D) bioprinting	341:374	three-dimensional (3D) bioprinting	341:374	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
35891601	3	46	theme	wound	643:647	arg1	healing					649:655	wound healing	643:655	wound healing purposes	643:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	47	theme	human	589:593	arg1	hMSC-EXOs					619:627	hMSC-EXOs	619:627	hMSC-EXOs	619:627	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	47	theme	human	589:593	arg1	cells					612:616	human mesenchymal stem cells	589:616	human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	589:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	48	theme	acid	467:470	arg1	system					557:562	a delivery system	546:562	a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	546:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	48	theme	acid	467:470	arg1	bioink					479:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	a methacrylated hyaluronic acid (MeHA) bioink	440:484	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	49	theme	smart	529:533	arg1	patches					535:541	advanced smart patches	520:541	advanced smart patches	520:541	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	1	50	theme	dressings	234:242	arg1	development					196:206	the development	192:206	the development of innovative smart wound dressings	192:242	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	2	51	theme	wound	267:271	arg1	complexity					249:258	The complexity	245:258	The complexity of the wound	245:271	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
35891601	6	52	from	process	1082:1088	arg1	cells					1133:1137	human endothelial cells	1115:1137	human endothelial cells	1115:1137	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	6	52	from	process	1082:1088	arg1	fibroblasts					1099:1109	human fibroblasts	1093:1109	human fibroblasts	1093:1109	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	1	53	theme	Wound	155:159	arg1	management					166:175	Wound care management	155:175	Wound care management	155:175	Wound care management urgently needs the development of innovative smart wound dressings.					
35891601	3	54	theme	suitable	630:637	arg1	hMSC-EXOs					619:627	hMSC-EXOs	619:627	hMSC-EXOs	619:627	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	54	theme	suitable	630:637	arg1	cells					612:616	human mesenchymal stem cells	589:616	human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	589:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	5	55	theme	improved	796:803	arg1	performance					816:826	improved mechanical performance	796:826	improved mechanical performance	796:826	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	5	56	theme	extended	857:864	arg1	time					878:881	extended degradation time	857:881	extended degradation time	857:881	The 3D printed MeHA patches revealed improved mechanical performance, appropriate swelling ratio, extended degradation time, and suitable biocompatibility.					
35891601	3	57	attach	derived	576:582	arg1	hMSC-EXOs					619:627	hMSC-EXOs	619:627	hMSC-EXOs	619:627	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	57	attach	derived	576:582	arg2	exosomes					567:574	exosomes	567:574	exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	567:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	3	57	attach	derived	576:582	arg1	cells					612:616	human mesenchymal stem cells	589:616	human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes	589:664	In this view, in the present work a methacrylated hyaluronic acid (MeHA) bioink was tested for the fabrication of advanced smart patches as a delivery system of exosomes derived from human mesenchymal stem cells (hMSC-EXOs) suitable for wound healing purposes.					
35891601	6	58	theme	angiogenic	1002:1011	arg1	ability					1013:1019	angiogenic ability	1002:1019	angiogenic ability	1002:1019	Furthermore, MeHA patches loaded with hMSC-EXOs improved the proliferation, migration, angiogenic ability, and expression of specific markers related to wound healing process in human fibroblasts and human endothelial cells.					
35891601	0	59	theme	hyaluronic	64:73	arg1	acid					75:78	methacrylated hyaluronic acid	50:78	methacrylated hyaluronic acid	50:78	Exosomes of mesenchymal stem cells delivered from methacrylated hyaluronic acid patch improve the regenerative properties of endothelial and dermal cells.					
35891601	2	60	theme	bioprinting	364:374	arg1	advent					331:336	the advent	327:336	the advent of three-dimensional (3D) bioprinting	327:374	The complexity of the wound often requires the use of personalized medication and the advent of three-dimensional (3D) bioprinting fits strongly with this need.					
37169048	10	0	theme	cinnamon	951:958	arg1	BgBs					960:963	plain and cinnamon BgBs	941:963	plain and cinnamon BgBs	941:963	The sensory evaluation of plain and cinnamon BgBs did not significantly differ from one another.					
37169048	5	1	contain	had	577:579	arg1	BgBs					572:575	Cinnamon BgBs	563:575	Cinnamon BgBs	563:575	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	5	1	contain	had	577:579	arg2	activity					606:613	44.44 % more antioxidant activity	581:613	44.44 % more antioxidant activity	581:613	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	5	2	theme	plain	627:631	arg1	BgBs					633:636	plain BgBs	627:636	plain BgBs (40.20 %)	627:646	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	5	2	theme	plain	627:631	arg1	%					645:645	40.20 %	639:645	40.20 %	639:645	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	2	3	theme	sensory	319:325	arg1	analysis					327:334	sensory analysis	319:334	sensory analysis	319:334	Morphology, oxidative stability, microbiological, chemical, and sensory analysis were assessed.					
37169048	1	4	theme	alginate	222:229	arg1	hydrogel					231:238	alginate hydrogel	222:238	alginate hydrogel	222:238	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	10	5	theme	plain	941:945	arg1	BgBs					960:963	plain and cinnamon BgBs	941:963	plain and cinnamon BgBs	941:963	The sensory evaluation of plain and cinnamon BgBs did not significantly differ from one another.					
37169048	6	6	theme	log	707:709	arg1	cycles					711:716	>7 log cycles	704:716	>7 log cycles	704:716	Moreover, BgBs products kept their probiotic counts at >7 log cycles.					
37169048	2	7	theme	oxidative	267:275	arg1	stability					277:285	oxidative stability	267:285	oxidative stability	267:285	Morphology, oxidative stability, microbiological, chemical, and sensory analysis were assessed.					
37169048	0	8	theme	novel	80:84	arg1	structure					86:94	A novel structure	78:94	A novel structure for nutritious spreadable butter	78:127	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	10	9	dep	one	999:1001	arg1	another					1003:1009	another	1003:1009	another	1003:1009	The sensory evaluation of plain and cinnamon BgBs did not significantly differ from one another.					
37169048	6	10	theme	>7	704:705	arg1	cycles					711:716	>7 log cycles	704:716	>7 log cycles	704:716	Moreover, BgBs products kept their probiotic counts at >7 log cycles.					
37169048	7	11	theme	lower	743:747	arg1	load					759:762	a lower microbial load	741:762	a lower microbial load	741:762	The cinnamon BgBs had a lower microbial load than plain BgBs.					
37169048	0	12	theme	nutritious	100:109	arg1	butter					122:127	nutritious spreadable butter	100:127	nutritious spreadable butter	100:127	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	7	13	theme	microbial	749:757	arg1	load					759:762	a lower microbial load	741:762	a lower microbial load	741:762	The cinnamon BgBs had a lower microbial load than plain BgBs.					
37169048	11	14	theme	storage	1035:1041	arg1	addition					1051:1058	the addition	1047:1058	the addition of the cinnamon oil	1047:1078	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	11	14	theme	storage	1035:1041	arg1	period					1025:1030	the period	1021:1030	the period of storage	1021:1041	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	6	15	theme	probiotic	684:692	arg1	counts					694:699	their probiotic counts	678:699	their probiotic counts	678:699	Moreover, BgBs products kept their probiotic counts at >7 log cycles.					
37169048	7	16	contain	had	737:739	arg2	load					759:762	a lower microbial load	741:762	a lower microbial load	741:762	The cinnamon BgBs had a lower microbial load than plain BgBs.					
37169048	7	16	contain	had	737:739	arg1	BgBs					732:735	The cinnamon BgBs	719:735	The cinnamon BgBs	719:735	The cinnamon BgBs had a lower microbial load than plain BgBs.					
37169048	1	17	theme	bigel	167:171	arg1	replacement					135:145	a replacement	133:145	a replacement for saturated fats	133:164	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	1	17	theme	bigel	167:171	arg1	BgBs					188:191	BgBs	188:191	BgBs	188:191	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	1	17	theme	bigel	167:171	arg1	spread					180:185	bigel butter spread	167:185	bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel	167:238	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	0	18	theme	Bigel	0:4	arg1	formulations					6:17	Bigel formulations	0:17	Bigel formulations	0:17	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	5	19	theme	Cinnamon	563:570	arg1	BgBs					572:575	Cinnamon BgBs	563:575	Cinnamon BgBs	563:575	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	11	20	theme	cinnamon	1067:1074	arg1	oil					1076:1078	the cinnamon oil	1063:1078	the cinnamon oil	1063:1078	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	7	21	theme	cinnamon	723:730	arg1	BgBs					732:735	The cinnamon BgBs	719:735	The cinnamon BgBs	719:735	The cinnamon BgBs had a lower microbial load than plain BgBs.					
37169048	1	22	theme	butter	173:178	arg1	replacement					135:145	a replacement	133:145	a replacement for saturated fats	133:164	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	1	22	theme	butter	173:178	arg1	BgBs					188:191	BgBs	188:191	BgBs	188:191	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	1	22	theme	butter	173:178	arg1	spread					180:185	bigel butter spread	167:185	bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel	167:238	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	9	23	theme	pH	865:866	arg1	values					868:873	the pH values	861:873	the pH values	861:873	But the pH values slightly dropped with the storage time.					
37169048	0	24	theme	spreadable	111:120	arg1	butter					122:127	nutritious spreadable butter	100:127	nutritious spreadable butter	100:127	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	1	25	theme	saturated	151:159	arg1	fats					161:164	saturated fats	151:164	saturated fats	151:164	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	3	26	theme	fatty	393:397	arg1	acids					399:403	unsaturated fatty acids	381:403	unsaturated fatty acids	381:403	The results demonstrated that unsaturated fatty acids were higher in cinnamon (73.87 %) than in plain (71.57 %) BgBs.					
37169048	11	27	theme	oil	1076:1078	arg1	addition					1051:1058	the addition	1047:1058	the addition of the cinnamon oil	1047:1078	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	11	27	theme	oil	1076:1078	arg1	period					1025:1030	the period	1021:1030	the period of storage	1021:1041	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	8	28	theme	chemical	785:792	arg1	composition					794:804	The chemical composition	781:804	The chemical composition of the BgBs products	781:825	The chemical composition of the BgBs products did not change significantly.					
37169048	0	29	theme	sesame	28:33	arg1	oleogel					35:41	sesame oleogel	28:41	sesame oleogel with probiotics alginate hydrogel	28:75	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	3	30	dep	higher	410:415	arg1	%					436:436	73.87 %	430:436	73.87 %	430:436	The results demonstrated that unsaturated fatty acids were higher in cinnamon (73.87 %) than in plain (71.57 %) BgBs.					
37169048	0	31	theme	probiotics	48:57	arg1	hydrogel					68:75	probiotics alginate hydrogel	48:75	probiotics alginate hydrogel	48:75	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	5	32	theme	more	589:592	arg1	activity					606:613	44.44 % more antioxidant activity	581:613	44.44 % more antioxidant activity	581:613	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	6	33	theme	BgBs	659:662	arg1	products					664:671	BgBs products	659:671	BgBs products	659:671	Moreover, BgBs products kept their probiotic counts at >7 log cycles.					
37169048	3	34	theme	plain	447:451	arg1	%					460:460	71.57 %	454:460	71.57 %	454:460	The results demonstrated that unsaturated fatty acids were higher in cinnamon (73.87 %) than in plain (71.57 %) BgBs.					
37169048	3	34	theme	plain	447:451	arg1	BgBs					463:466	plain (71.57 %) BgBs	447:466	plain (71.57 %) BgBs	447:466	The results demonstrated that unsaturated fatty acids were higher in cinnamon (73.87 %) than in plain (71.57 %) BgBs.					
37169048	3	35	theme	unsaturated	381:391	arg1	acids					399:403	unsaturated fatty acids	381:403	unsaturated fatty acids	381:403	The results demonstrated that unsaturated fatty acids were higher in cinnamon (73.87 %) than in plain (71.57 %) BgBs.					
37169048	5	36	theme	antioxidant	594:604	arg1	activity					606:613	44.44 % more antioxidant activity	581:613	44.44 % more antioxidant activity	581:613	Cinnamon BgBs had 44.44 % more antioxidant activity compared to plain BgBs (40.20 %).					
37169048	8	37	theme	products	818:825	arg1	composition					794:804	The chemical composition	781:804	The chemical composition of the BgBs products	781:825	The chemical composition of the BgBs products did not change significantly.					
37169048	4	38	theme	peroxide	473:480	arg1	higher					492:497	higher	492:497	higher	492:497	The peroxide value was higher in plain (5.25 meqO2/kg) than in cinnamon BgBs (4.29 meqO2/kg).					
37169048	4	38	theme	peroxide	473:480	arg1	value					482:486	The peroxide value	469:486	The peroxide value	469:486	The peroxide value was higher in plain (5.25 meqO2/kg) than in cinnamon BgBs (4.29 meqO2/kg).					
37169048	11	39	theme	flavor	1107:1112	arg1	ratings					1114:1120	the flavor ratings	1103:1120	the flavor ratings	1103:1120	However, the period of storage and the addition of the cinnamon oil significantly affected the flavor ratings.					
37169048	8	40	theme	BgBs	813:816	arg1	products					818:825	the BgBs products	809:825	the BgBs products	809:825	The chemical composition of the BgBs products did not change significantly.					
37169048	9	41	theme	storage	901:907	arg1	time					909:912	the storage time	897:912	the storage time	897:912	But the pH values slightly dropped with the storage time.					
37169048	4	42	theme	cinnamon	532:539	arg1	4.29 meqO2/kg					547:559	4.29 meqO2/kg	547:559	4.29 meqO2/kg	547:559	The peroxide value was higher in plain (5.25 meqO2/kg) than in cinnamon BgBs (4.29 meqO2/kg).					
37169048	4	42	theme	cinnamon	532:539	arg1	BgBs					541:544	cinnamon BgBs	532:544	cinnamon BgBs (4.29 meqO2/kg)	532:560	The peroxide value was higher in plain (5.25 meqO2/kg) than in cinnamon BgBs (4.29 meqO2/kg).					
37169048	10	43	theme	sensory	919:925	arg1	evaluation					927:936	The sensory evaluation	915:936	The sensory evaluation of plain and cinnamon BgBs	915:963	The sensory evaluation of plain and cinnamon BgBs did not significantly differ from one another.					
37169048	0	44	dep	based	19:23	arg1	structure					86:94	A novel structure	78:94	A novel structure for nutritious spreadable butter	78:127	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	1	45	theme	sesame	203:208	arg1	oleogel					210:216	sesame oleogel	203:216	sesame oleogel	203:216	As a replacement for saturated fats, bigel butter spread (BgBs) based on sesame oleogel and alginate hydrogel was developed.					
37169048	0	46	theme	alginate	59:66	arg1	hydrogel					68:75	probiotics alginate hydrogel	48:75	probiotics alginate hydrogel	48:75	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	10	47	theme	BgBs	960:963	arg1	evaluation					927:936	The sensory evaluation	915:936	The sensory evaluation of plain and cinnamon BgBs	915:963	The sensory evaluation of plain and cinnamon BgBs did not significantly differ from one another.					
37169048	0	48	with	oleogel	35:41	arg1	hydrogel					68:75	probiotics alginate hydrogel	48:75	probiotics alginate hydrogel	48:75	Bigel formulations based on sesame oleogel with probiotics alginate hydrogel: A novel structure for nutritious spreadable butter.					
37169048	7	49	theme	plain	769:773	arg1	BgBs					775:778	plain BgBs	769:778	plain BgBs	769:778	The cinnamon BgBs had a lower microbial load than plain BgBs.					
35636194	0	0	theme	porous	79:84	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	0	1	from	detection	17:25	arg1	juices					45:50	juices	45:50	juices based on mung bean-derived porous carbon@chitosan composite	45:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	3	2	theme	adhesion	651:658	arg1	capacity					660:667	adhesion capacity	651:667	adhesion capacity	651:667	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	3	theme	CTS	419:421	arg1	composite					423:431	the MBC@CTS composite	411:431	the MBC@CTS composite	411:431	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	1	4	theme	chitosan	243:250	arg1	composite					262:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	5	used	used	283:286	arg2	composite					262:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	6	theme	glassy	304:309	arg1	GCE					329:331	GCE	329:331	GCE	329:331	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	6	theme	glassy	304:309	arg1	electrode					318:326	the glassy carbon electrode	300:326	the glassy carbon electrode (GCE)	300:332	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	7	theme	simple	159:164	arg1	strategy					179:186	a simple and scalable strategy	157:186	a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE)	157:332	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	0	8	theme	@	92:92	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	1	9	theme	carbon	311:316	arg1	GCE					329:331	GCE	329:331	GCE	329:331	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	9	theme	carbon	311:316	arg1	electrode					318:326	the glassy carbon electrode	300:326	the glassy carbon electrode (GCE)	300:332	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	6	10	theme	%	1184:1184	arg1	recoveries					1160:1169	satisfactory recoveries	1147:1169	satisfactory recoveries	1147:1169	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	10	theme	%	1184:1184	arg1	%					1184:1184	98.8-103.2%	1174:1184	98.8-103.2%	1174:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	10	theme	%	1184:1184	arg1	%					1141:1141	2.4 %-4.2%	1132:1141	2.4 %-4.2%	1132:1141	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	11	theme	%	1136:1136	arg1	%					1184:1184	98.8-103.2%	1174:1184	98.8-103.2%	1174:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	11	theme	%	1136:1136	arg1	%					1141:1141	2.4 %-4.2%	1132:1141	2.4 %-4.2%	1132:1141	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	12	theme	hierarchical	461:472	arg1	structure					474:482	three-dimensional hierarchical structure	443:482	three-dimensional hierarchical structure	443:482	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	4	13	theme	@	677:677	arg1	sensor					686:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	1	14	theme	MBC	253:255	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	14	theme	MBC	253:255	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	0	15	theme	carbon	86:91	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	6	16	theme	apple	1068:1072	arg1	juices					1085:1090	apple and tomato juices	1068:1090	apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1068:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	17	with	MBC	434:436	arg1	structure					474:482	three-dimensional hierarchical structure	443:482	three-dimensional hierarchical structure	443:482	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	5	18	theme	concentration	835:847	arg1	range					849:853	a linear concentration range	826:853	a linear concentration range from 0.1 to 20 μM	826:871	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	1	19	theme	@	256:256	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	19	theme	@	256:256	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	6	20	theme	CBZ	1051:1053	arg1	detection					1055:1063	the CBZ detection	1047:1063	the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1047:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	4	21	theme	MBC	674:676	arg1	sensor					686:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	4	22	theme	electrochemical	713:727	arg1	performance					739:749	wonderful electrochemical detection performance	703:749	wonderful electrochemical detection performance towards CBZ	703:761	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	4	23	theme	detection	729:737	arg1	performance					739:749	wonderful electrochemical detection performance	703:749	wonderful electrochemical detection performance towards CBZ	703:761	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	2	24	theme	@	342:342	arg1	sensor					351:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor was applied for the carbendazim (CBZ) detection.					
35636194	0	25	theme	chitosan	93:100	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	6	26	theme	recoveries	1160:1169	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	27	theme	three-dimensional	443:459	arg1	structure					474:482	three-dimensional hierarchical structure	443:482	three-dimensional hierarchical structure	443:482	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	1	28	theme	scalable	170:177	arg1	strategy					179:186	a simple and scalable strategy	157:186	a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE)	157:332	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	0	29	theme	sensitive	7:15	arg1	detection					17:25	Highly sensitive detection	0:25	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite	0:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	0	30	theme	bean-derived	66:77	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	6	31	theme	satisfactory	1147:1158	arg1	recoveries					1160:1169	satisfactory recoveries	1147:1169	satisfactory recoveries	1147:1169	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	5	32	from	20 μM	867:871	arg1	range					849:853	a linear concentration range	826:853	a linear concentration range from 0.1 to 20 μM	826:871	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	3	33	theme	specific	500:507	arg1	area					517:520	large specific surface area	494:520	large specific surface area	494:520	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	2	34	theme	carbendazim	378:388	arg1	detection					396:404	the carbendazim (CBZ) detection	374:404	the carbendazim (CBZ) detection	374:404	The MBC@CTS/GCE sensor was applied for the carbendazim (CBZ) detection.					
35636194	6	35	with	juices	1085:1090	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	36	theme	good	591:594	arg1	property					609:616	good film-forming property	591:616	good film-forming property	591:616	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	1	37	link	bean-derived	216:227	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	37	link	bean-derived	216:227	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	3	38	theme	surface	509:515	arg1	area					517:520	large specific surface area	494:520	large specific surface area	494:520	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	6	39	theme	standard	1110:1117	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	0	40	theme	electrochemical	121:135	arg1	sensor					137:142	electrochemical sensor	121:142	electrochemical sensor	121:142	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	4	41	theme	CTS/GCE	678:684	arg1	sensor					686:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor	670:691	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	6	42	theme	%	1141:1141	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	43	theme	good	968:971	arg1	reproducibility					973:987	good reproducibility	968:987	good reproducibility	968:987	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	5	44	theme	optimized	774:782	arg1	conditions					784:793	the optimized conditions	770:793	the optimized conditions	770:793	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	1	45	theme	composite	262:270	arg1	preparation					196:206	the preparation	192:206	the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE)	192:332	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	6	46	from	detection	1055:1063	arg1	juices					1085:1090	apple and tomato juices	1068:1090	apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1068:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	47	theme	low	1097:1099	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	48	theme	large	494:498	arg1	area					517:520	large specific surface area	494:520	large specific surface area	494:520	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	5	49	theme	CTS/GCE	804:810	arg1	sensor					812:817	the MBC@CTS/GCE sensor	796:817	the MBC@CTS/GCE sensor	796:817	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	3	50	theme	good	523:526	arg1	adsorbability					528:540	good adsorbability	523:540	good adsorbability	523:540	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	0	51	theme	carbendazim	30:40	arg1	detection					17:25	Highly sensitive detection	0:25	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite	0:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	5	52	theme	MBC	800:802	arg1	sensor					812:817	the MBC@CTS/GCE sensor	796:817	the MBC@CTS/GCE sensor	796:817	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	1	53	theme	mung	211:214	arg1	composite					262:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	6	54	theme	fabricated	945:954	arg1	sensor					956:961	the fabricated sensor	941:961	the fabricated sensor with good reproducibility, stability, and selectivity	941:1015	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	5	55	theme	detection	902:910	arg1	limit					893:897	relatively low limit	878:897	relatively low limit of detection (LOD) of 20 nM	878:925	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	0	56	link	bean-derived	66:77	arg1	composite					102:110	bean-derived porous carbon@chitosan composite	66:110	bean-derived porous carbon@chitosan composite	66:110	Highly sensitive detection of carbendazim in juices based on mung bean-derived porous carbon@chitosan composite modified electrochemical sensor.					
35636194	3	57	theme	MBC	415:417	arg1	composite					423:431	the MBC@CTS composite	411:431	the MBC@CTS composite	411:431	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	58	theme	hydrophilicity	619:632	arg1	performance					634:644	hydrophilicity performance	619:644	hydrophilicity performance	619:644	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	6	59	with	sensor	956:961	arg1	stability					990:998	stability	990:998	stability	990:998	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	59	with	sensor	956:961	arg1	selectivity					1005:1015	selectivity	1005:1015	selectivity	1005:1015	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	6	59	with	sensor	956:961	arg1	reproducibility					973:987	good reproducibility	968:987	good reproducibility	968:987	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	60	theme	film-forming	596:607	arg1	property					609:616	good film-forming property	591:616	good film-forming property	591:616	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	61	theme	@	418:418	arg1	composite					423:431	the MBC@CTS composite	411:431	the MBC@CTS composite	411:431	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	62	theme	high	547:550	arg1	conductivity					563:574	high electrical conductivity	547:574	high electrical conductivity	547:574	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	5	63	theme	low	889:891	arg1	limit					893:897	relatively low limit	878:897	relatively low limit of detection (LOD) of 20 nM	878:925	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	1	64	theme	bean-derived	216:227	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	64	theme	bean-derived	216:227	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	4	65	theme	wonderful	703:711	arg1	performance					739:749	wonderful electrochemical detection performance	703:749	wonderful electrochemical detection performance towards CBZ	703:761	The MBC@CTS/GCE sensor exhibited wonderful electrochemical detection performance towards CBZ.					
35636194	3	66	theme	electrical	552:561	arg1	conductivity					563:574	high electrical conductivity	547:574	high electrical conductivity	547:574	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	5	67	theme	@	803:803	arg1	sensor					812:817	the MBC@CTS/GCE sensor	796:817	the MBC@CTS/GCE sensor	796:817	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	5	68	theme	linear	828:833	arg1	range					849:853	a linear concentration range	826:853	a linear concentration range from 0.1 to 20 μM	826:871	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	5	69	dep	20 μM	867:871	arg1	to					864:865	to	864:865	to	864:865	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	1	70	theme	porous	229:234	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	70	theme	porous	229:234	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	2	71	theme	CTS/GCE	343:349	arg1	sensor					351:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor was applied for the carbendazim (CBZ) detection.					
35636194	5	72	theme	20 nM	921:925	arg1	detection					902:910	detection	902:910	detection (LOD) of 20 nM	902:925	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	5	72	theme	20 nM	921:925	arg1	LOD					913:915	LOD	913:915	LOD	913:915	Under the optimized conditions, the MBC@CTS/GCE sensor showed a linear concentration range from 0.1 to 20 μM with relatively low limit of detection (LOD) of 20 nM.					
35636194	6	73	theme	tomato	1078:1083	arg1	juices					1085:1090	apple and tomato juices	1068:1090	apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1068:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	2	74	theme	MBC	339:341	arg1	sensor					351:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor	335:356	The MBC@CTS/GCE sensor was applied for the carbendazim (CBZ) detection.					
35636194	1	75	theme	carbon	236:241	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	75	theme	carbon	236:241	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	6	76	theme	relative	1101:1108	arg1	deviation					1119:1127	low relative standard deviation	1097:1127	low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%	1097:1184	In addition, the fabricated sensor with good reproducibility, stability, and selectivity were successfully applied for the CBZ detection in apple and tomato juices with low relative standard deviation of 2.4 %-4.2% and satisfactory recoveries of 98.8-103.2%.					
35636194	3	77	contain	had	587:589	arg2	property					609:616	good film-forming property	591:616	good film-forming property	591:616	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	77	contain	had	587:589	arg2	capacity					660:667	adhesion capacity	651:667	adhesion capacity	651:667	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	77	contain	had	587:589	arg1	CTS					583:585	CTS	583:585	CTS	583:585	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	3	77	contain	had	587:589	arg2	performance					634:644	hydrophilicity performance	619:644	hydrophilicity performance	619:644	For the MBC@CTS composite, MBC with three-dimensional hierarchical structure presented large specific surface area, good adsorbability, and high electrical conductivity, while CTS had good film-forming property, hydrophilicity performance, and adhesion capacity.					
35636194	1	78	theme	@	242:242	arg1	CTS					257:259	MBC@CTS	253:259	MBC@CTS	253:259	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
35636194	1	78	theme	@	242:242	arg1	chitosan					243:250	bean-derived porous carbon@chitosan	216:250	mung bean-derived porous carbon@chitosan (MBC@CTS) composite	211:270	We reported a simple and scalable strategy for the preparation of mung bean-derived porous carbon@chitosan (MBC@CTS) composite, which was used to optimize the glassy carbon electrode (GCE).					
36828091	6	0	used	occupied	961:968	arg2	site					949:952	each effective site	934:952	each effective site	934:952	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	9	1	theme	exponent	1393:1400	arg1	values					1402:1407	the obtained diffusion exponent values	1370:1407	the obtained diffusion exponent values (>0.45)	1370:1415	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	9	1	theme	exponent	1393:1400	arg1	>0.45					1410:1414	>0.45	1410:1414	>0.45	1410:1414	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	0	2	theme	enhanced	84:91	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	2	theme	enhanced	84:91	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	1	3	theme	Natural	158:164	arg1	D					187:187	D	187:187	D	187:187	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	3	theme	Natural	158:164	arg1	frustules					176:184	Natural diatomite frustules	158:184	Natural diatomite frustules (D)	158:188	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	10	4	theme	cell	1572:1575	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	0	5	theme	oxaliplatin	104:114	arg1	drug					116:119	oxaliplatin drug	104:119	oxaliplatin drug	104:119	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	10	6	theme	cell	1658:1661	arg1	viability					1663:1671	3.16 % cell viability	1651:1671	3.16 % cell viability	1651:1671	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	6	theme	cell	1658:1661	arg1	CF/ZD					1644:1648	CF/ZD	1644:1648	CF/ZD (3.16 % cell viability)	1644:1672	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	7	from	CF/ZD	1644:1648	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	8	theme	cell	1623:1626	arg1	viability					1628:1636	cell viability	1623:1636	9.76 % cell viability	1616:1636	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	9	theme	3.16 	1651:1655	arg1	%					1656:1656	%	1656:1656	%	1656:1656	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	7	10	theme	encapsulation	1177:1189	arg1	reactions					1191:1199	the encapsulation reactions	1173:1199	the encapsulation reactions	1173:1199	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	10	11	dep	%	1621:1621	arg1	viability					1628:1636	cell viability	1623:1636	9.76 % cell viability	1616:1636	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	9	12	theme	release	1336:1342	arg1	studies					1352:1358	The release kinetic studies	1332:1358	The release kinetic studies involving the obtained diffusion exponent values (>0.45)	1332:1415	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	1	13	theme	zeolitized	277:286	arg1	ZD					299:300	ZD	299:300	ZD	299:300	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	13	theme	zeolitized	277:286	arg1	diatomite					288:296	zeolitized diatomite	277:296	zeolitized diatomite (ZD)	277:301	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	4	14	theme	kinetic	712:718	arg1	order					706:710	the classic Pseudo-first order kinetic	681:718	the classic Pseudo-first order kinetic (R2 > 0.93)	681:730	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	4	14	theme	kinetic	712:718	arg1	R2 > 0.93					721:729	R2 > 0.93	721:729	R2 > 0.93	721:729	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	2	15	with	carriers	414:421	arg1	properties					464:473	enhanced properties	455:473	enhanced properties	455:473	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	6	16	theme	vertical	1014:1021	arg1	forms					1023:1027	vertical forms	1014:1027	vertical forms involving multi-molecular mechanisms	1014:1064	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	6	17	theme	multi-molecular	1039:1053	arg1	mechanisms					1055:1064	multi-molecular mechanisms	1039:1064	multi-molecular mechanisms	1039:1064	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	1	18	theme	diatomite	166:174	arg1	D					187:187	D	187:187	D	187:187	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	18	theme	diatomite	166:174	arg1	frustules					176:184	Natural diatomite frustules	158:184	Natural diatomite frustules (D)	158:188	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	0	19	theme	drug	116:119	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	19	theme	drug	116:119	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	10	20	from	ZD	1612:1613	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	8	21	theme	release	1206:1212	arg1	profiles					1214:1221	The release profiles	1202:1221	The release profiles of ZD as well as CF/ZD	1202:1244	The release profiles of ZD as well as CF/ZD exhibit slow and controlled properties for about 100 h either at pH 5.5 or at pH 7.4.					
36828091	9	22	theme	kinetic	1344:1350	arg1	studies					1352:1358	The release kinetic studies	1332:1358	The release kinetic studies involving the obtained diffusion exponent values (>0.45)	1332:1415	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	8	23	theme	ZD	1226:1227	arg1	profiles					1214:1221	The release profiles	1202:1221	The release profiles of ZD as well as CF/ZD	1202:1244	The release profiles of ZD as well as CF/ZD exhibit slow and controlled properties for about 100 h either at pH 5.5 or at pH 7.4.					
36828091	0	24	theme	release	131:137	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	24	theme	release	131:137	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	5	25	theme	estimated	783:791	arg1	density					822:828	The estimated effective encapsulation site density	779:828	The estimated effective encapsulation site density of CF/ZD	779:837	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	25	theme	estimated	783:791	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	10	26	theme	cancer	1565:1570	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	3	27	theme	encapsulation	570:582	arg1	capacities					584:593	significantly enhanced encapsulation capacities	547:593	significantly enhanced encapsulation capacities	547:593	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	6	28	dep	3	981:981	arg1	to					978:979	to	978:979	to	978:979	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	4	29	theme	classic	685:691	arg1	order					706:710	the classic Pseudo-first order kinetic	681:718	the classic Pseudo-first order kinetic (R2 > 0.93)	681:730	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	4	29	theme	classic	685:691	arg1	R2 > 0.93					721:729	R2 > 0.93	721:729	R2 > 0.93	721:729	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	5	30	theme	CF/ZD	833:837	arg1	density					822:828	The estimated effective encapsulation site density	779:828	The estimated effective encapsulation site density of CF/ZD	779:837	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	30	theme	CF/ZD	833:837	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	7	31	theme	encapsulation	1071:1083	arg1	energy					1085:1090	The encapsulation energy	1067:1090	The encapsulation energy (<40 KJ/mol)	1067:1103	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	7	31	theme	encapsulation	1071:1083	arg1	KJ/mol					1097:1102	<40 KJ/mol	1093:1102	<40 KJ/mol	1093:1102	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	5	32	theme	higher	872:877	arg1	value					879:883	a notably higher value	862:883	a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	862:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	32	theme	higher	872:877	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	4	33	theme	Langmuir	748:755	arg1	R2 = 0.99					767:775	R2 = 0.99	767:775	R2 = 0.99	767:775	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	4	33	theme	Langmuir	748:755	arg1	isotherm					757:764	traditional Langmuir isotherm	736:764	traditional Langmuir isotherm (R2 = 0.99)	736:776	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	0	34	theme	zeolitic	59:66	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	34	theme	zeolitic	59:66	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	9	35	theme	diffusion	1383:1391	arg1	values					1402:1407	the obtained diffusion exponent values	1370:1407	the obtained diffusion exponent values (>0.45)	1370:1415	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	9	35	theme	diffusion	1383:1391	arg1	>0.45					1410:1414	>0.45	1410:1414	>0.45	1410:1414	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	10	36	theme	cell	1595:1598	arg1	viability					1600:1608	cell viability	1595:1608	18.78 % cell viability	1587:1608	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	37	dep	%	1593:1593	arg1	viability					1600:1608	cell viability	1595:1608	18.78 % cell viability	1587:1608	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	2	38	theme	drug	438:441	arg1	carriers					414:421	potential carriers	404:421	potential carriers of oxaliplatin drug (OXPL) with enhanced properties	404:473	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	2	38	theme	drug	438:441	arg1	products					378:385	The modified products	365:385	The modified products	365:385	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	7	39	theme	physical	1146:1153	arg1	mechanisms					1155:1164	the physical mechanisms	1142:1164	the physical mechanisms	1142:1164	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	0	40	theme	loading	122:128	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	40	theme	loading	122:128	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	3	41	theme	enhanced	561:568	arg1	capacities					584:593	significantly enhanced encapsulation capacities	547:593	significantly enhanced encapsulation capacities	547:593	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	2	42	theme	oxaliplatin	426:436	arg1	OXPL					444:447	OXPL	444:447	OXPL	444:447	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	2	42	theme	oxaliplatin	426:436	arg1	drug					438:441	oxaliplatin drug	426:441	oxaliplatin drug (OXPL)	426:448	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	5	43	theme	effective	793:801	arg1	density					822:828	The estimated effective encapsulation site density	779:828	The estimated effective encapsulation site density of CF/ZD	779:837	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	43	theme	effective	793:801	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	6	44	theme	effective	939:947	arg1	site					949:952	each effective site	934:952	each effective site	934:952	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	10	45	dep	D	1584:1584	arg1	%					1593:1593	18.78 %	1587:1593	18.78 % cell viability	1587:1608	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	9	46	theme	erosion/diffusion	1461:1477	arg1	mechanism					1487:1495	non-Fickian transport and complex erosion/diffusion release mechanism	1427:1495	mechanism	1487:1495	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	8	47	theme	CF/ZD	1240:1244	arg1	profiles					1214:1221	The release profiles	1202:1221	The release profiles of ZD as well as CF/ZD	1202:1244	The release profiles of ZD as well as CF/ZD exhibit slow and controlled properties for about 100 h either at pH 5.5 or at pH 7.4.					
36828091	4	48	theme	encapsulation	650:662	arg1	reactions					664:672	The occurred encapsulation reactions	637:672	The occurred encapsulation reactions	637:672	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	2	49	theme	potential	404:412	arg1	carriers					414:421	potential carriers	404:421	potential carriers of oxaliplatin drug (OXPL) with enhanced properties	404:473	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	2	49	theme	potential	404:412	arg1	products					378:385	The modified products	365:385	The modified products	365:385	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	10	50	dep	ZD	1612:1613	arg1	%					1621:1621	9.76 %	1616:1621	9.76 % cell viability	1616:1636	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	0	51	theme	cellulose	34:42	arg1	characterization					14:29	characterization	14:29	characterization	14:29	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	51	theme	cellulose	34:42	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	1	52	dep	zeolitization	211:223	arg1	processes					257:265	functionalization processes	239:265	functionalization processes	239:265	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	3	53	theme	raw	610:612	arg1	65.9 mg/g					625:633	65.9 mg/g	625:633	65.9 mg/g	625:633	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	3	53	theme	raw	610:612	arg1	diatomite					614:622	raw diatomite	610:622	raw diatomite (65.9 mg/g)	610:634	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	4	54	theme	occurred	641:648	arg1	reactions					664:672	The occurred encapsulation reactions	637:672	The occurred encapsulation reactions	637:672	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	5	55	theme	site	817:820	arg1	density					822:828	The estimated effective encapsulation site density	779:828	The estimated effective encapsulation site density of CF/ZD	779:837	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	55	theme	site	817:820	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	1	56	theme	cellulose	307:315	arg1	CF/ZD					357:361	CF/ZD	357:361	CF/ZD	357:361	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	56	theme	cellulose	307:315	arg1	composite					346:354	cellulose fibrous/zeolitized diatomite composite	307:354	cellulose fibrous/zeolitized diatomite composite (CF/ZD)	307:362	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	0	57	theme	cytotoxicity	144:155	arg1	carrier					93:99	an enhanced carrier	81:99	an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity	81:155	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	0	57	theme	cytotoxicity	144:155	arg1	diatomite					68:76	zeolitic diatomite	59:76	zeolitic diatomite	59:76	Synthesis and characterization of cellulose functionalized zeolitic diatomite as an enhanced carrier of oxaliplatin drug; loading, release, and cytotoxicity.					
36828091	10	58	theme	%	1656:1656	arg1	viability					1663:1671	3.16 % cell viability	1651:1671	3.16 % cell viability	1651:1671	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	10	58	theme	%	1656:1656	arg1	CF/ZD					1644:1648	CF/ZD	1644:1648	CF/ZD (3.16 % cell viability)	1644:1672	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	2	59	theme	enhanced	455:462	arg1	properties					464:473	enhanced properties	455:473	enhanced properties	455:473	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	1	60	theme	fibrous/zeolitized	317:334	arg1	CF/ZD					357:361	CF/ZD	357:361	CF/ZD	357:361	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	60	theme	fibrous/zeolitized	317:334	arg1	composite					346:354	cellulose fibrous/zeolitized diatomite composite	307:354	cellulose fibrous/zeolitized diatomite composite (CF/ZD)	307:362	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	10	61	theme	cytotoxic	1532:1540	arg1	effects					1542:1548	enhanced cytotoxic effects	1523:1548	enhanced cytotoxic effects on the HCT-116 cancer cell lines	1523:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	9	62	theme	complex	1453:1459	arg1	mechanism					1487:1495	non-Fickian transport and complex erosion/diffusion release mechanism	1427:1495	mechanism	1487:1495	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	8	63	theme	controlled	1263:1272	arg1	properties					1274:1283	slow and controlled properties	1254:1283	slow and controlled properties for about 100 h	1254:1299	The release profiles of ZD as well as CF/ZD exhibit slow and controlled properties for about 100 h either at pH 5.5 or at pH 7.4.					
36828091	1	64	theme	diatomite	336:344	arg1	CF/ZD					357:361	CF/ZD	357:361	CF/ZD	357:361	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	1	64	theme	diatomite	336:344	arg1	composite					346:354	cellulose fibrous/zeolitized diatomite composite	307:354	cellulose fibrous/zeolitized diatomite composite (CF/ZD)	307:362	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
36828091	10	65	theme	enhanced	1523:1530	arg1	effects					1542:1548	enhanced cytotoxic effects	1523:1548	enhanced cytotoxic effects on the HCT-116 cancer cell lines	1523:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	7	66	theme	predominant	1119:1129	arg1	effects					1131:1137	the predominant effects	1115:1137	the predominant effects of the physical mechanisms during the encapsulation reactions	1115:1199	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	4	67	theme	Pseudo-first	693:704	arg1	order					706:710	the classic Pseudo-first order kinetic	681:718	the classic Pseudo-first order kinetic (R2 > 0.93)	681:730	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	4	67	theme	Pseudo-first	693:704	arg1	R2 > 0.93					721:729	R2 > 0.93	721:729	R2 > 0.93	721:729	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	3	68	theme	prepared	480:487	arg1	structures					528:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	6	69	theme	OXPL	996:999	arg1	molecules					1001:1009	OXPL molecules	996:1009	OXPL molecules	996:1009	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	10	70	from	D	1584:1584	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	7	71	theme	mechanisms	1155:1164	arg1	effects					1131:1137	the predominant effects	1115:1137	the predominant effects of the physical mechanisms during the encapsulation reactions	1115:1199	The encapsulation energy (<40 KJ/mol) suggested the predominant effects of the physical mechanisms during the encapsulation reactions.					
36828091	3	72	theme	ZD	489:490	arg1	structures					528:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	4	73	theme	traditional	736:746	arg1	R2 = 0.99					767:775	R2 = 0.99	767:775	R2 = 0.99	767:775	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	4	73	theme	traditional	736:746	arg1	isotherm					757:764	traditional Langmuir isotherm	736:764	traditional Langmuir isotherm (R2 = 0.99)	736:776	The occurred encapsulation reactions follow the classic Pseudo-first order kinetic (R2 > 0.93) and traditional Langmuir isotherm (R2 = 0.99).					
36828091	9	74	theme	release	1479:1485	arg1	mechanism					1487:1495	non-Fickian transport and complex erosion/diffusion release mechanism	1427:1495	mechanism	1487:1495	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	6	75	theme	molecules	1001:1009	arg1	molecules					983:991	up to 3 molecules	975:991	up to 3 molecules of OXPL molecules	975:1009	Moreover, each effective site can be occupied with up to 3 molecules of OXPL molecules in vertical forms involving multi-molecular mechanisms.					
36828091	8	76	theme	slow	1254:1257	arg1	properties					1274:1283	slow and controlled properties	1254:1283	slow and controlled properties for about 100 h	1254:1299	The release profiles of ZD as well as CF/ZD exhibit slow and controlled properties for about 100 h either at pH 5.5 or at pH 7.4.					
36828091	3	77	theme	CF/ZD	509:513	arg1	structures					528:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures	476:537	The prepared ZD (112.5 mg/g) and CF/ZD (268.3 mg/g) structures exhibit significantly enhanced encapsulation capacities as compared to raw diatomite (65.9 mg/g).					
36828091	9	78	theme	obtained	1374:1381	arg1	values					1402:1407	the obtained diffusion exponent values	1370:1407	the obtained diffusion exponent values (>0.45)	1370:1415	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	9	78	theme	obtained	1374:1381	arg1	>0.45					1410:1414	>0.45	1410:1414	>0.45	1410:1414	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	10	79	from	effects	1542:1548	arg1	lines					1577:1581	the HCT-116 cancer cell lines	1553:1581	the HCT-116 cancer cell lines	1553:1581	These structures exhibit enhanced cytotoxic effects on the HCT-116 cancer cell lines (D (18.78 % cell viability), ZD (9.76 % cell viability), and CF/ZD (3.16 % cell viability).					
36828091	9	80	theme	non-Fickian	1427:1437	arg1	transport					1439:1447	non-Fickian transport and complex erosion/diffusion release mechanism	1427:1495	transport	1439:1447	The release kinetic studies involving the obtained diffusion exponent values (>0.45) suggested non-Fickian transport and complex erosion/diffusion release mechanism.					
36828091	5	81	theme	encapsulation	803:815	arg1	density					822:828	The estimated effective encapsulation site density	779:828	The estimated effective encapsulation site density of CF/ZD	779:837	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	5	81	theme	encapsulation	803:815	arg1	104.8 mg/g					842:851	104.8 mg/g	842:851	104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g)	842:921	The estimated effective encapsulation site density of CF/ZD is 104.8 mg/g which is a notably higher value than ZD (44.6 mg/g) and D (28.4 mg/g).					
36828091	2	82	theme	modified	369:376	arg1	carriers					414:421	potential carriers	404:421	potential carriers of oxaliplatin drug (OXPL) with enhanced properties	404:473	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	2	82	theme	modified	369:376	arg1	products					378:385	The modified products	365:385	The modified products	365:385	The modified products were assessed as potential carriers of oxaliplatin drug (OXPL) with enhanced properties.					
36828091	1	83	theme	functionalization	239:255	arg1	processes					257:265	functionalization processes	239:265	functionalization processes	239:265	Natural diatomite frustules (D) were incorporated in zeolitization and cellulose functionalization processes to obtain zeolitized diatomite (ZD) and cellulose fibrous/zeolitized diatomite composite (CF/ZD).					
35798724	6	0	theme	conditioned	920:930	arg1	media					932:936	conditioned media	920:936	conditioned media from cultured radula cells	920:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	1	1	theme	unique	141:146	arg1	biomaterial					84:94	The biomaterial	80:94	The biomaterial with the highest known tensile strength	80:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	1	theme	unique	141:146	arg1	goethite					172:179	goethite	172:179	goethite	172:179	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	1	theme	unique	141:146	arg1	chitin					161:166	chitin	161:166	chitin	161:166	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	1	theme	unique	141:146	arg1	composite					148:156	a unique composite	139:156	a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata)	139:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	3	2	from	cells	483:487	arg1	culture					492:498	culture	492:498	culture	492:498	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	4	3	theme	Transcriptomic	536:549	arg1	analysis					551:558	Transcriptomic analysis	536:558	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate,	536:646	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	3	4	theme	isolated	456:463	arg1	tissue					472:477	isolated limpet tissue	456:477	isolated limpet tissue	456:477	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	4	5	theme	genes	695:699	arg1	expression					681:690	expression	681:690	expression of genes related to chitin and iron processing	681:737	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	2	6	from	based	265:269	arg1	tooth					281:285	limpet tooth	274:285	limpet tooth	274:285	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	7	7	with	biomimetic	1095:1104	arg1	properties					1122:1131	comparable properties	1111:1131	comparable properties	1111:1131	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	4	8	theme	related	701:707	arg1	genes					695:699	genes	695:699	genes related to chitin and iron processing	695:737	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	6	9	theme	radula	952:957	arg1	cells					959:963	cultured radula cells	943:963	cultured radula cells	943:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	3	10	theme	biomimetic	513:522	arg1	structures					524:533	new biomimetic structures	509:533	new biomimetic structures	509:533	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	6	11	theme	Bioinspired	843:853	arg1	material					855:862	Bioinspired material	843:862	Bioinspired material	843:862	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	6	12	theme	cultured	943:950	arg1	cells					959:963	cultured radula cells	943:963	cultured radula cells	943:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	7	13	theme	comparable	1111:1120	arg1	properties					1122:1131	comparable properties	1111:1131	comparable properties	1111:1131	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	3	14	dep	ex	441:442	arg1	vivo					444:447	vivo	444:447	vivo	444:447	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	1	15	theme	Common	219:224	arg1	vulgata					242:248	the Common Limpet (Patella vulgata)	215:249	the Common Limpet (Patella vulgata)	215:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	5	16	from	processes	778:786	arg1	radula					795:800	the radula	791:800	the radula	791:800	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	3	17	theme	developmental	417:429	arg1	processes					431:439	limpet tooth developmental processes	404:439	limpet tooth developmental processes	404:439	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	5	18	theme	radula	820:825	arg1	cells					827:831	isolated radula cells	811:831	isolated radula cells	811:831	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	5	19	theme	iron	752:755	arg1	processes					778:786	iron and chitin metabolic processes	752:786	iron and chitin metabolic processes in the radula	752:800	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	1	20	from	vulgata	242:248	arg1	teeth					204:208	teeth	204:208	teeth from the Common Limpet (Patella vulgata)	204:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	4	21	theme	iron	723:726	arg1	processing					728:737	iron processing	723:737	iron processing	723:737	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	1	22	theme	chitin	161:166	arg1	biomaterial					84:94	The biomaterial	80:94	The biomaterial with the highest known tensile strength	80:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	22	theme	chitin	161:166	arg1	goethite					172:179	goethite	172:179	goethite	172:179	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	22	theme	chitin	161:166	arg1	chitin					161:166	chitin	161:166	chitin	161:166	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	22	theme	chitin	161:166	arg1	composite					148:156	a unique composite	139:156	a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata)	139:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	2	23	theme	biomimetic	254:263	arg1	based					265:269	A biomimetic based	252:269	A biomimetic based	252:269	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	2	23	theme	biomimetic	254:263	arg1	desirable					356:364	desirable	356:364	desirable	356:364	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	4	24	theme	limpet	624:629	arg1	teeth					631:635	limpet teeth	624:635	limpet teeth	624:635	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	0	25	theme	Biomimetic	0:9	arg1	generation					11:20	Biomimetic generation	0:20	Biomimetic generation of the strongest known biomaterial	0:55	Biomimetic generation of the strongest known biomaterial found in limpet tooth.					
35798724	1	26	theme	Limpet	226:231	arg1	vulgata					242:248	the Common Limpet (Patella vulgata)	215:249	the Common Limpet (Patella vulgata)	215:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	6	27	from	cells	959:963	arg1	media					932:936	conditioned media	920:936	conditioned media from cultured radula cells	920:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	1	28	theme	goethite	172:179	arg1	biomaterial					84:94	The biomaterial	80:94	The biomaterial with the highest known tensile strength	80:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	28	theme	goethite	172:179	arg1	goethite					172:179	goethite	172:179	goethite	172:179	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	28	theme	goethite	172:179	arg1	chitin					161:166	chitin	161:166	chitin	161:166	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	28	theme	goethite	172:179	arg1	composite					148:156	a unique composite	139:156	a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata)	139:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	5	29	theme	metabolic	768:776	arg1	processes					778:786	iron and chitin metabolic processes	752:786	iron and chitin metabolic processes in the radula	752:800	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	5	30	theme	chitin	761:766	arg1	processes					778:786	iron and chitin metabolic processes	752:786	iron and chitin metabolic processes in the radula	752:800	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	7	31	theme	tooth	1037:1041	arg1	generation					1016:1025	the generation	1012:1025	the generation of limpet tooth	1012:1041	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	1	32	attach	present	193:199	arg1	teeth					204:208	teeth	204:208	teeth from the Common Limpet (Patella vulgata)	204:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	32	attach	present	193:199	arg2	chitin					161:166	chitin	161:166	chitin	161:166	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	3	33	theme	tooth	411:415	arg1	processes					431:439	limpet tooth developmental processes	404:439	limpet tooth developmental processes	404:439	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	1	34	with	biomaterial	84:94	arg1	strength					127:134	the highest known tensile strength	101:134	the highest known tensile strength	101:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	35	theme	Patella	234:240	arg1	vulgata					242:248	the Common Limpet (Patella vulgata)	215:249	the Common Limpet (Patella vulgata)	215:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	3	36	theme	new	509:511	arg1	structures					524:533	new biomimetic structures	509:533	new biomimetic structures	509:533	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	4	37	from	radula	595:600	arg1	organ					607:611	the organ	603:611	the organ	603:611	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	3	38	theme	limpet	465:470	arg1	tissue					472:477	isolated limpet tissue	456:477	isolated limpet tissue	456:477	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	0	39	theme	known	39:43	arg1	biomaterial					45:55	the strongest known biomaterial	25:55	the strongest known biomaterial	25:55	Biomimetic generation of the strongest known biomaterial found in limpet tooth.					
35798724	2	40	theme	limpet	274:279	arg1	tooth					281:285	limpet tooth	274:285	limpet tooth	274:285	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	1	41	from	teeth	204:208	arg1	present					193:199	present	193:199	present	193:199	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	2	42	with	based	265:269	arg1	properties					335:344	corresponding high-performance mechanical properties	293:344	corresponding high-performance mechanical properties	293:344	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	2	43	theme	mechanical	324:333	arg1	properties					335:344	corresponding high-performance mechanical properties	293:344	corresponding high-performance mechanical properties	293:344	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	0	44	theme	strongest	29:37	arg1	biomaterial					45:55	the strongest known biomaterial	25:55	the strongest known biomaterial	25:55	Biomimetic generation of the strongest known biomaterial found in limpet tooth.					
35798724	6	45	theme	mineralised	905:915	arg1	chitin					898:903	electrospun chitin	886:903	electrospun chitin mineralised by conditioned media from cultured radula cells	886:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	7	46	theme	limpet	1030:1035	arg1	tooth					1037:1041	limpet tooth	1030:1041	limpet tooth	1030:1041	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	4	47	theme	sequential	659:668	arg1	changes					670:676	sequential changes	659:676	sequential changes in expression of genes related to chitin and iron processing	659:737	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	3	48	theme	limpet	404:409	arg1	processes					431:439	limpet tooth developmental processes	404:439	limpet tooth developmental processes	404:439	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	7	49	theme	biomimetic	1095:1104	arg1	development					1072:1082	development	1072:1082	development of a novel biomimetic with comparable properties	1072:1131	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	1	50	from	present	193:199	arg1	teeth					204:208	teeth	204:208	teeth from the Common Limpet (Patella vulgata)	204:249	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	7	51	theme	molecular	985:993	arg1	processes					995:1003	molecular processes	985:1003	molecular processes behind the generation of limpet tooth	985:1041	Our results inform molecular processes behind the generation of limpet tooth and establish a platform for development of a novel biomimetic with comparable properties.					
35798724	1	52	theme	highest	105:111	arg1	strength					127:134	the highest known tensile strength	101:134	the highest known tensile strength	101:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	0	53	theme	biomaterial	45:55	arg1	generation					11:20	Biomimetic generation	0:20	Biomimetic generation of the strongest known biomaterial	0:55	Biomimetic generation of the strongest known biomaterial found in limpet tooth.					
35798724	6	54	theme	electrospun	886:896	arg1	chitin					898:903	electrospun chitin	886:903	electrospun chitin mineralised by conditioned media from cultured radula cells	886:963	Bioinspired material can be developed with electrospun chitin mineralised by conditioned media from cultured radula cells.					
35798724	1	55	dep	chitin	161:166	arg1	α-FeO					182:186	α-FeO	182:186	α-FeO(OH)	182:190	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	55	dep	chitin	161:166	arg1	OH					188:189	OH	188:189	OH	188:189	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	3	56	from	tissue	472:477	arg1	culture					492:498	culture	492:498	culture	492:498	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	1	57	theme	known	113:117	arg1	strength					127:134	the highest known tensile strength	101:134	the highest known tensile strength	101:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	1	58	theme	tensile	119:125	arg1	strength					127:134	the highest known tensile strength	101:134	the highest known tensile strength	101:134	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	4	59	theme	developmental	568:580	arg1	stage					582:586	each developmental stage	563:586	each developmental stage of the radula, the organ from which limpet teeth originate,	563:646	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	3	60	theme	ex	441:442	arg1	processes					431:439	limpet tooth developmental processes	404:439	limpet tooth developmental processes	404:439	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	4	61	from	changes	670:676	arg1	expression					681:690	expression	681:690	expression of genes related to chitin and iron processing	681:737	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	3	62	theme	processes	431:439	arg1	replication					389:399	the replication	385:399	the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures	385:533	Here we report on the replication of limpet tooth developmental processes ex vivo, where isolated limpet tissue and cells in culture generate new biomimetic structures.					
35798724	0	63	theme	limpet	66:71	arg1	tooth					73:77	limpet tooth	66:77	limpet tooth	66:77	Biomimetic generation of the strongest known biomaterial found in limpet tooth.					
35798724	4	64	theme	radula	595:600	arg1	stage					582:586	each developmental stage	563:586	each developmental stage of the radula, the organ from which limpet teeth originate,	563:646	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35798724	2	65	theme	high-performance	307:322	arg1	properties					335:344	corresponding high-performance mechanical properties	293:344	corresponding high-performance mechanical properties	293:344	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	5	66	theme	isolated	811:818	arg1	cells					827:831	isolated radula cells	811:831	isolated radula cells	811:831	We quantify iron and chitin metabolic processes in the radula and grow isolated radula cells in vitro.					
35798724	1	67	theme	present	193:199	arg1	chitin					161:166	chitin	161:166	chitin	161:166	The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata).					
35798724	2	68	theme	corresponding	293:305	arg1	properties					335:344	corresponding high-performance mechanical properties	293:344	corresponding high-performance mechanical properties	293:344	A biomimetic based on limpet tooth, with corresponding high-performance mechanical properties is highly desirable.					
35798724	4	69	theme	stage	582:586	arg1	analysis					551:558	Transcriptomic analysis	536:558	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate,	536:646	Transcriptomic analysis of each developmental stage of the radula, the organ from which limpet teeth originate, identifies sequential changes in expression of genes related to chitin and iron processing.					
35628555	8	0	theme	oxygen	1293:1298	arg1	species					1300:1306	reactive oxygen species	1284:1306	reactive oxygen species	1284:1306	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	1	theme	tumor	1151:1155	arg1	factor-α					1166:1173	an interleukin-1β + tumor necrosis factor-α	1131:1173	factor-α	1166:1173	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	1	2	theme	retinal	134:140	arg1	structure					142:150	the retinal structure	130:150	the retinal structure	130:150	The complexity of the retinal structure reflects on the difficulty to describe its composite cell interactions.					
35628555	9	3	theme	events	1458:1463	arg1	cascade					1447:1453	the cascade	1443:1453	the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit	1443:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	8	4	theme	pro-inflammatory	1101:1116	arg1	stimulus					1118:1125	The best pro-inflammatory stimulus	1092:1125	The best pro-inflammatory stimulus	1092:1125	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	4	theme	pro-inflammatory	1101:1116	arg1	interleukin-1β					1134:1147	an interleukin-1β + tumor necrosis factor-α	1131:1173	interleukin-1β	1134:1147	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	9	5	theme	co-culture	1496:1505	arg1	models					1507:1512	co-culture models	1496:1512	co-culture models involving microvascular cells	1496:1542	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	5	6	theme	morphologic	922:932	arg1	assays					949:954	morphologic and functional assays	922:954	morphologic and functional assays	922:954	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	1	7	theme	structure	142:150	arg1	complexity					116:125	The complexity	112:125	The complexity of the retinal structure	112:150	The complexity of the retinal structure reflects on the difficulty to describe its composite cell interactions.					
35628555	4	8	theme	inflammatory	796:807	arg1	response					810:817	a significant M1 (inflammatory) response	778:817	a significant M1 (inflammatory) response	778:817	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	2	9	theme	inflammatory	276:287	arg1	stimuli					289:295	inflammatory stimuli	276:295	inflammatory stimuli	276:295	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	4	10	theme	able	763:766	arg1	combination					751:761	the best combination	742:761	the best combination able to induce a significant M1 (inflammatory) response	742:817	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	3	11	theme	retinal	549:555	arg1	portions					557:564	the neuro-vascular retinal portions	530:564	the neuro-vascular retinal portions in species-specific models	530:591	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	5	12	theme	pro-	871:874	arg1	molecules					898:906	pro- and anti-inflammatory molecules	871:906	pro- and anti-inflammatory molecules	871:906	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	0	13	theme	Diabetic	90:97	arg1	Retinopathy					99:109	Diabetic Retinopathy	90:109	Diabetic Retinopathy	90:109	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	8	14	theme	inflammatory	1331:1342	arg1	cytokines					1344:1352	inflammatory cytokines	1331:1352	inflammatory cytokines	1331:1352	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	15	theme	morphology	1214:1223	arg1	changes					1225:1231	morphology changes	1214:1231	morphology changes	1214:1231	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	9	16	theme	neurovascular	1611:1623	arg1	unit					1625:1628	the neurovascular unit	1607:1628	the neurovascular unit	1607:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	2	17	theme	rodent	358:363	arg1	cells					365:369	rodent cells	358:369	rodent cells	358:369	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	3	18	theme	human	427:431	arg1	line					444:447	immortalized human microglial line	414:447	a commercially available immortalized human microglial line	389:447	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	6	19	theme	cells	1026:1030	arg1	derivation					1006:1015	the human microglial derivation	985:1015	the human microglial derivation of these cells	985:1030	Marker expression confirmed the human microglial derivation of these cells.					
35628555	2	20	theme	immune	257:262	arg1	reaction					264:271	the immune reaction	253:271	the immune reaction to inflammatory stimuli during diabetic retinopathy (DR)	253:328	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	3	21	theme	microglial	433:442	arg1	line					444:447	immortalized human microglial line	414:447	a commercially available immortalized human microglial line	389:447	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	9	22	theme	multifaceted	1578:1589	arg1	interactions					1591:1602	multifaceted interactions	1578:1602	multifaceted interactions of the neurovascular unit	1578:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	8	23	theme	interferon-γ	1177:1188	arg1	cocktail					1190:1197	interferon-γ cocktail	1177:1197	interferon-γ cocktail	1177:1197	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	24	theme	best	1096:1099	arg1	stimulus					1118:1125	The best pro-inflammatory stimulus	1092:1125	The best pro-inflammatory stimulus	1092:1125	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	24	theme	best	1096:1099	arg1	interleukin-1β					1134:1147	an interleukin-1β + tumor necrosis factor-α	1131:1173	interleukin-1β	1134:1147	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	9	25	theme	unit	1625:1628	arg1	interactions					1591:1602	multifaceted interactions	1578:1602	multifaceted interactions of the neurovascular unit	1578:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	3	26	theme	species-specific	569:584	arg1	models					586:591	species-specific models	569:591	species-specific models	569:591	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	3	27	theme	available	404:412	arg1	line					444:447	immortalized human microglial line	414:447	a commercially available immortalized human microglial line	389:447	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	8	28	theme	reactive	1284:1291	arg1	species					1300:1306	reactive oxygen species	1284:1306	reactive oxygen species	1284:1306	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	2	29	theme	diabetic	304:311	arg1	DR					326:327	DR	326:327	DR	326:327	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	2	29	theme	diabetic	304:311	arg1	retinopathy					313:323	diabetic retinopathy	304:323	diabetic retinopathy (DR)	304:328	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	4	30	theme	significant	780:790	arg1	response					810:817	a significant M1 (inflammatory) response	778:817	a significant M1 (inflammatory) response	778:817	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	3	31	theme	immortalized	414:425	arg1	line					444:447	immortalized human microglial line	414:447	a commercially available immortalized human microglial line	389:447	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	0	32	theme	Immortalized	23:34	arg1	Line					58:61	an Immortalized Human Microglial Cell Line	20:61	an Immortalized Human Microglial Cell Line	20:61	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	9	33	theme	microglial	1386:1395	arg1	line					1397:1400	this microglial line	1381:1400	this microglial line	1381:1400	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	0	34	theme	Retinopathy	99:109	arg1	Study					81:85	the Study	77:85	the Study of Diabetic Retinopathy	77:109	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	4	35	theme	pro-inflammatory	705:720	arg1	cocktails					722:730	several pro-inflammatory cocktails	697:730	several pro-inflammatory cocktails	697:730	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	9	36	theme	interactions	1591:1602	arg1	understanding					1561:1573	the understanding	1557:1573	the understanding of multifaceted interactions of the neurovascular unit	1557:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	4	37	theme	several	697:703	arg1	cocktails					722:730	several pro-inflammatory cocktails	697:730	several pro-inflammatory cocktails	697:730	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	0	38	theme	Microglial	42:51	arg1	Line					58:61	an Immortalized Human Microglial Cell Line	20:61	an Immortalized Human Microglial Cell Line	20:61	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	6	39	theme	microglial	995:1004	arg1	derivation					1006:1015	the human microglial derivation	985:1015	the human microglial derivation of these cells	985:1030	Marker expression confirmed the human microglial derivation of these cells.					
35628555	9	40	theme	microvascular	1524:1536	arg1	cells					1538:1542	microvascular cells	1524:1542	microvascular cells	1524:1542	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	5	41	theme	molecules	898:906	arg1	expression					857:866	the expression	853:866	the expression of pro- and anti-inflammatory molecules	853:906	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	4	42	theme	lipopolysaccharide	656:673	arg1	stimulation					681:691	lipopolysaccharide (LPS) stimulation	656:691	lipopolysaccharide (LPS) stimulation	656:691	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	0	43	theme	Human	36:40	arg1	Line					58:61	an Immortalized Human Microglial Cell Line	20:61	an Immortalized Human Microglial Cell Line	20:61	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	6	44	theme	human	989:993	arg1	derivation					1006:1015	the human microglial derivation	985:1015	the human microglial derivation of these cells	985:1030	Marker expression confirmed the human microglial derivation of these cells.					
35628555	5	45	theme	anti-inflammatory	880:896	arg1	molecules					898:906	pro- and anti-inflammatory molecules	871:906	pro- and anti-inflammatory molecules	871:906	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	5	46	theme	M1	832:833	arg1	induction					835:843	M1 induction	832:843	M1 induction	832:843	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	1	47	theme	composite	195:203	arg1	interactions					210:221	its composite cell interactions	191:221	its composite cell interactions	191:221	The complexity of the retinal structure reflects on the difficulty to describe its composite cell interactions.					
35628555	0	48	theme	Line	58:61	arg1	Characterization					0:15	Characterization	0:15	Characterization of an Immortalized Human Microglial Cell Line	0:61	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	5	49	theme	functional	938:947	arg1	assays					949:954	morphologic and functional assays	922:954	morphologic and functional assays	922:954	We measured M1 induction through the expression of pro- and anti-inflammatory molecules and performed morphologic and functional assays.					
35628555	0	50	theme	Cell	53:56	arg1	Line					58:61	an Immortalized Human Microglial Cell Line	20:61	an Immortalized Human Microglial Cell Line	20:61	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	7	51	theme	M1	1080:1081	arg1	profile					1083:1089	a M1 profile	1078:1089	a M1 profile	1078:1089	Differently from rodents, LPS did not induce a M1 profile.					
35628555	3	52	from	portions	557:564	arg1	models					586:591	species-specific models	569:591	species-specific models	569:591	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	8	53	theme	necrosis	1157:1164	arg1	factor-α					1166:1173	an interleukin-1β + tumor necrosis factor-α	1131:1173	factor-α	1166:1173	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	9	54	dep	DR.	1476:1478	arg1	help					1549:1552	help	1549:1552	will help in the understanding of multifaceted interactions of the neurovascular unit	1544:1628	In conclusion, this microglial line proved potentially useful to investigate the cascade of events leading to DR. In perspective, co-culture models involving microvascular cells will help in the understanding of multifaceted interactions of the neurovascular unit.					
35628555	4	55	theme	best	746:749	arg1	combination					751:761	the best combination	742:761	the best combination able to induce a significant M1 (inflammatory) response	742:817	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	1	56	theme	cell	205:208	arg1	interactions					210:221	its composite cell interactions	191:221	its composite cell interactions	191:221	The complexity of the retinal structure reflects on the difficulty to describe its composite cell interactions.					
35628555	4	57	theme	M1	792:793	arg1	response					810:817	a significant M1 (inflammatory) response	778:817	a significant M1 (inflammatory) response	778:817	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	3	58	theme	neuro-vascular	534:547	arg1	portions					557:564	the neuro-vascular retinal portions	530:564	the neuro-vascular retinal portions in species-specific models	530:591	We characterized a commercially available immortalized human microglial line and tested its susceptibility to inflammation, to study the interactions between the neuro-vascular retinal portions in species-specific models.					
35628555	8	59	theme	cytokines	1344:1352	arg1	apoptosis					1262:1270	apoptosis	1262:1270	apoptosis	1262:1270	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	59	theme	cytokines	1344:1352	arg1	proliferation					1247:1259	proliferation	1247:1259	proliferation	1247:1259	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	59	theme	cytokines	1344:1352	arg1	species					1300:1306	reactive oxygen species	1284:1306	reactive oxygen species	1284:1306	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	59	theme	cytokines	1344:1352	arg1	expression					1317:1326	the expression	1313:1326	the expression of inflammatory cytokines and miRNAs	1313:1363	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	59	theme	cytokines	1344:1352	arg1	migration					1273:1281	migration	1273:1281	migration	1273:1281	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	2	60	theme	most	335:338	arg1	studies					340:346	most studies	335:346	most studies	335:346	Microglia is responsible for the immune reaction to inflammatory stimuli during diabetic retinopathy (DR), but most studies still use rodent cells.					
35628555	4	61	theme	markers	638:644	arg1	expression					613:622	the expression	609:622	the expression of microglial markers	609:644	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
35628555	6	62	theme	Marker	957:962	arg1	expression					964:973	Marker expression	957:973	Marker expression	957:973	Marker expression confirmed the human microglial derivation of these cells.					
35628555	0	63	dep	Characterization	0:15	arg1	Tool					68:71	a Tool	66:71	a Tool for the Study of Diabetic Retinopathy	66:109	Characterization of an Immortalized Human Microglial Cell Line as a Tool for the Study of Diabetic Retinopathy.					
35628555	8	64	theme	miRNAs	1358:1363	arg1	apoptosis					1262:1270	apoptosis	1262:1270	apoptosis	1262:1270	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	64	theme	miRNAs	1358:1363	arg1	proliferation					1247:1259	proliferation	1247:1259	proliferation	1247:1259	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	64	theme	miRNAs	1358:1363	arg1	species					1300:1306	reactive oxygen species	1284:1306	reactive oxygen species	1284:1306	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	64	theme	miRNAs	1358:1363	arg1	expression					1317:1326	the expression	1313:1326	the expression of inflammatory cytokines and miRNAs	1313:1363	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	8	64	theme	miRNAs	1358:1363	arg1	migration					1273:1281	migration	1273:1281	migration	1273:1281	The best pro-inflammatory stimulus was an interleukin-1β + tumor necrosis factor-α + interferon-γ cocktail, which induced morphology changes and increased proliferation, apoptosis, migration, reactive oxygen species, and the expression of inflammatory cytokines and miRNAs.					
35628555	4	65	theme	microglial	627:636	arg1	markers					638:644	microglial markers	627:644	microglial markers	627:644	After checking the expression of microglial markers, we tried lipopolysaccharide (LPS) stimulation and several pro-inflammatory cocktails to select the best combination able to induce a significant M1 (inflammatory) response.					
36403767	3	0	theme	interactions	655:666	arg1	existence					632:640	existence	632:640	existence of secondary interactions confirmed by FT-IR analysis	632:694	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	4	1	theme	test	841:844	arg1	results					846:852	Mechanical test results	830:852	Mechanical test results	830:852	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	6	2	theme	good	1074:1077	arg1	activity					1093:1100	good antibacterial activity	1074:1100	good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli	1074:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	6	3	theme	In-vitro	1046:1053	arg1	studies					1055:1061	In-vitro studies	1046:1061	In-vitro studies	1046:1061	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	0	4	theme	wound	113:117	arg1	healing					119:125	wound healing	113:125	wound healing	113:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	9	5	theme	wound	1625:1629	arg1	applications					1636:1647	wound care applications	1625:1647	wound care applications	1625:1647	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	8	6	theme	prominent	1461:1469	arg1	healing					1477:1483	prominent wound healing	1461:1483	prominent wound healing (96.5 %)	1461:1492	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	8	6	theme	prominent	1461:1469	arg1	%					1491:1491	96.5 %	1486:1491	96.5 %	1486:1491	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	9	7	theme	developed	1558:1566	arg1	biomaterial					1610:1620	biomaterial	1610:1620	biomaterial	1610:1620	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	9	7	theme	developed	1558:1566	arg1	film					1582:1585	developed bio-composite film	1558:1585	developed bio-composite film	1558:1585	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	2	8	theme	healing	538:544	arg1	application					546:556	wound healing application	532:556	wound healing application	532:556	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	6	9	theme	bacterial	1130:1138	arg1	strains					1140:1146	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	3	10	theme	alcohol	597:603	arg1	matrix					615:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	2	11	theme	film	466:469	arg1	preparation					369:379	the preparation	365:379	the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	365:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	6	12	theme	foremost	1110:1117	arg1	strains					1140:1146	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	1	13	theme	Natural	128:134	arg1	material					164:171	Natural extract-based bio-composite material	128:171	Natural extract-based bio-composite material for wound healing	128:189	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	2	14	theme	based	446:450	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	15	theme	scratch	1404:1410	arg1	assay					1412:1416	in-vitro scratch assay	1395:1416	in-vitro scratch assay	1395:1416	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	0	16	theme	/chitosan	57:65	arg1	films					77:81	poly (vinyl alcohol)/chitosan composite films	37:81	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	1	17	theme	human	320:324	arg1	well-being					326:335	the human well-being	316:335	the human well-being	316:335	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	1	18	theme	bio-composite	150:162	arg1	material					164:171	Natural extract-based bio-composite material	128:171	Natural extract-based bio-composite material for wound healing	128:189	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	4	19	from	improvement	748:758	arg1	flexibility					763:773	flexibility	763:773	flexibility	763:773	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	5	20	theme	transmission	913:924	arg1	rate					926:929	water vapor transmission rate	901:929	water vapor transmission rate (∼70.07 %)	901:940	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	20	theme	transmission	913:924	arg1	%					939:939	∼70.07 %	932:939	∼70.07 %	932:939	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	2	21	theme	solvent	479:485	arg1	technique					495:503	solvent casting technique	479:503	solvent casting technique	479:503	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	22	theme	adhesion	1427:1434	arg1	results					1441:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	0	23	dep	films	77:81	arg1	bio-material					96:107	A promising bio-material	84:107	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	7	24	theme	amplified	1239:1247	arg1	property					1278:1285	amplified anti-inflammatory (∼79.38 %) property	1239:1285	amplified anti-inflammatory (∼79.38 %) property	1239:1285	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	25	theme	alba	422:425	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	4	26	theme	thermal	714:720	arg1	stability					722:730	thermal stability	714:730	thermal stability	714:730	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	0	27	theme	Basella	0:6	arg1	extract					18:24	Basella alba stem extract	0:24	Basella alba stem extract	0:24	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	7	28	theme	anti-inflammatory	1249:1265	arg1	property					1278:1285	amplified anti-inflammatory (∼79.38 %) property	1239:1285	amplified anti-inflammatory (∼79.38 %) property	1239:1285	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	29	theme	vinyl	390:394	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	0	30	theme	stem	13:16	arg1	extract					18:24	Basella alba stem extract	0:24	Basella alba stem extract	0:24	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	1	31	theme	wound	270:274	arg1	film					285:288	commercial wound dressing film	259:288	commercial wound dressing film	259:288	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	5	32	theme	water	901:905	arg1	rate					926:929	water vapor transmission rate	901:929	water vapor transmission rate (∼70.07 %)	901:940	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	32	theme	water	901:905	arg1	%					939:939	∼70.07 %	932:939	∼70.07 %	932:939	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	2	33	theme	BAE	441:443	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	2	34	theme	Poly	384:387	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	1	35	theme	film	285:288	arg1	cost					251:254	high cost	246:254	high cost of commercial wound dressing film	246:288	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	7	36	dep	film	1230:1233	arg1	has					1235:1237	has	1235:1237	has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1235:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	7	37	theme	vinyl	1206:1210	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	38	theme	extract	432:438	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	3	39	theme	/Chitosan	605:613	arg1	matrix					615:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	1	40	theme	serious	297:303	arg1	problem					305:311	serious problem	297:311	serious problem	297:311	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	9	41	theme	bio-composite	1568:1580	arg1	biomaterial					1610:1620	biomaterial	1610:1620	biomaterial	1610:1620	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	9	41	theme	bio-composite	1568:1580	arg1	film					1582:1585	developed bio-composite film	1558:1585	developed bio-composite film	1558:1585	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	7	42	theme	Poly	1200:1203	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	3	43	theme	secondary	645:653	arg1	interactions					655:666	secondary interactions	645:666	secondary interactions confirmed by FT-IR analysis	645:694	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	7	44	theme	BAE	1185:1187	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	0	45	theme	vinyl	43:47	arg1	poly					37:40	poly	37:40	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	0	45	theme	vinyl	43:47	arg1	alcohol					49:55	vinyl alcohol	43:55	vinyl alcohol	43:55	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	9	46	used	utilized	1596:1603	arg2	film					1582:1585	developed bio-composite film	1558:1585	developed bio-composite film	1558:1585	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	9	46	used	utilized	1596:1603	arg2	biomaterial					1610:1620	biomaterial	1610:1620	biomaterial	1610:1620	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	9	47	theme	work	1539:1542	arg1	results					1516:1522	Overall results	1508:1522	Overall results of the present work	1508:1542	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	3	48	theme	FT-IR	681:685	arg1	analysis					687:694	FT-IR analysis	681:694	FT-IR analysis	681:694	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	1	49	theme	infection	232:240	arg1	risk					224:227	risk	224:227	risk of infection	224:240	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	1	50	theme	high	246:249	arg1	cost					251:254	high cost	246:254	high cost of commercial wound dressing film	246:288	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	7	51	theme	cytotoxicity	1363:1374	arg1	results					1376:1382	cytotoxicity results	1363:1382	cytotoxicity results	1363:1382	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	4	52	theme	Mechanical	830:839	arg1	results					846:852	Mechanical test results	830:852	Mechanical test results	830:852	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	6	53	theme	antibacterial	1079:1091	arg1	activity					1093:1100	good antibacterial activity	1074:1100	good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli	1074:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	1	54	theme	wound	177:181	arg1	healing					183:189	wound healing	177:189	wound healing	177:189	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	5	55	theme	BAE	1033:1035	arg1	content					1037:1043	BAE content	1033:1043	BAE content	1033:1043	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	7	56	theme	excellent	1310:1318	arg1	biocompatibility					1320:1335	excellent biocompatibility	1310:1335	excellent biocompatibility (94.9 %)	1310:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	7	56	theme	excellent	1310:1318	arg1	%					1343:1343	94.9 %	1338:1343	94.9 %	1338:1343	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	3	57	theme	BAE	576:578	arg1	Incorporation					559:571	Incorporation	559:571	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix	559:620	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	1	58	theme	much	202:205	arg1	attention					207:215	much attention	202:215	much attention	202:215	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	5	59	theme	Hydrophilic	869:879	arg1	property					881:888	Hydrophilic property	869:888	Hydrophilic property (∼9.04 %)	869:898	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	59	theme	Hydrophilic	869:879	arg1	%					897:897	∼9.04 %	891:897	∼9.04 %	891:897	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	9	60	theme	care	1631:1634	arg1	applications					1636:1647	wound care applications	1625:1647	wound care applications	1625:1647	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	3	61	theme	vinyl	591:595	arg1	matrix					615:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	9	62	from	applications	1636:1647	arg1	biomaterial					1610:1620	biomaterial	1610:1620	biomaterial	1610:1620	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	9	62	from	applications	1636:1647	arg1	film					1582:1585	developed bio-composite film	1558:1585	developed bio-composite film	1558:1585	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	2	63	theme	wound	532:536	arg1	healing					538:544	wound healing	532:544	wound healing application	532:556	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	64	theme	in-vitro	1395:1402	arg1	assay					1412:1416	in-vitro scratch assay	1395:1416	in-vitro scratch assay	1395:1416	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	6	65	theme	infectious	1119:1128	arg1	strains					1140:1146	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	foremost infectious bacterial strains S. aureus and E. coli	1110:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	4	66	theme	Good	697:700	arg1	%					783:783	∼63.38 %	776:783	∼63.38 %	776:783	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	4	66	theme	Good	697:700	arg1	morphology					702:711	Good morphology	697:711	Good morphology	697:711	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	5	67	theme	degradation	974:984	arg1	rate					986:989	degradation rate	974:989	degradation rate (∼14.04 %)	974:1000	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	67	theme	degradation	974:984	arg1	%					999:999	∼14.04 %	992:999	∼14.04 %	992:999	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	3	68	theme	Poly	585:588	arg1	matrix					615:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Poly (vinyl alcohol)/Chitosan matrix	585:620	Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.					
36403767	2	69	theme	bio-composite	452:464	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	70	theme	assay	1412:1416	arg1	results					1441:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	6	71	dep	strains	1140:1146	arg1	aureus					1151:1156	S. aureus	1148:1156	S. aureus	1148:1156	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	6	71	dep	strains	1140:1146	arg1	coli					1165:1168	E. coli	1162:1168	E. coli	1162:1168	In-vitro studies have shown good antibacterial activity against foremost infectious bacterial strains S. aureus and E. coli.					
36403767	0	72	theme	composite	67:75	arg1	films					77:81	poly (vinyl alcohol)/chitosan composite films	37:81	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	1	73	theme	extract-based	136:148	arg1	material					164:171	Natural extract-based bio-composite material	128:171	Natural extract-based bio-composite material for wound healing	128:189	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	9	74	from	biomaterial	1610:1620	arg1	applications					1636:1647	wound care applications	1625:1647	wound care applications	1625:1647	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	8	75	theme	cell	1422:1425	arg1	adhesion					1427:1434	cell adhesion	1422:1434	cell adhesion	1422:1434	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	5	76	theme	vapor	907:911	arg1	rate					926:929	water vapor transmission rate	901:929	water vapor transmission rate (∼70.07 %)	901:940	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	76	theme	vapor	907:911	arg1	%					939:939	∼70.07 %	932:939	∼70.07 %	932:939	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	2	77	theme	casting	487:493	arg1	technique					495:503	solvent casting technique	479:503	solvent casting technique	479:503	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	78	theme	test	1436:1439	arg1	results					1441:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	in-vitro scratch assay and cell adhesion test results	1395:1447	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	4	79	theme	significant	736:746	arg1	improvement					748:758	significant improvement	736:758	significant improvement in flexibility	736:773	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	0	80	theme	promising	86:94	arg1	bio-material					96:107	A promising bio-material	84:107	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	0	81	theme	alba	8:11	arg1	extract					18:24	Basella alba stem extract	0:24	Basella alba stem extract	0:24	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	4	82	from	stability	722:730	arg1	flexibility					763:773	flexibility	763:773	flexibility	763:773	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	7	83	theme	/Chitosan	1220:1228	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	84	theme	/Chitosan/Basella	404:420	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	8	85	theme	wound	1471:1475	arg1	healing					1477:1483	prominent wound healing	1461:1483	prominent wound healing (96.5 %)	1461:1492	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	8	85	theme	wound	1471:1475	arg1	%					1491:1491	96.5 %	1486:1491	96.5 %	1486:1491	Moreover, in-vitro scratch assay and cell adhesion test results illustrated prominent wound healing (96.5 %) and adhesion.					
36403767	1	86	theme	commercial	259:268	arg1	film					285:288	commercial wound dressing film	259:288	commercial wound dressing film	259:288	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	7	87	theme	alcohol	1212:1218	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	88	theme	alcohol	396:402	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	0	89	theme	poly	37:40	arg1	films					77:81	poly (vinyl alcohol)/chitosan composite films	37:81	poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing	37:125	Basella alba stem extract integrated poly (vinyl alcohol)/chitosan composite films: A promising bio-material for wound healing.					
36403767	1	90	theme	dressing	276:283	arg1	film					285:288	commercial wound dressing film	259:288	commercial wound dressing film	259:288	Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being.					
36403767	5	91	theme	swelling	943:950	arg1	ability					952:958	swelling ability	943:958	swelling ability (∼14.7 %)	943:968	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	91	theme	swelling	943:950	arg1	%					967:967	∼14.7 %	961:967	∼14.7 %	961:967	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	5	92	from	increase	1021:1028	arg1	content					1037:1043	BAE content	1033:1043	BAE content	1033:1043	Hydrophilic property (∼9.04 %), water vapor transmission rate (∼70.07 %), swelling ability (∼14.7 %) and degradation rate (∼14.04 %) were enhanced with increase in BAE content.					
36403767	9	93	theme	Overall	1508:1514	arg1	results					1516:1522	Overall results	1508:1522	Overall results of the present work	1508:1542	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36403767	7	94	theme	integrated	1189:1198	arg1	film					1230:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film	1185:1233	BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %)	1185:1344	Additionally, BAE integrated Poly (vinyl alcohol)/Chitosan film has amplified anti-inflammatory (∼79.38 %) property, hemocompatibility and excellent biocompatibility (94.9 %) was displayed by cytotoxicity results.					
36403767	2	95	theme	stem	427:430	arg1	film					466:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film	384:469	Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application.					
36403767	4	96	theme	films	793:797	arg1	stability					722:730	thermal stability	714:730	thermal stability	714:730	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	4	96	theme	films	793:797	arg1	improvement					748:758	significant improvement	736:758	significant improvement in flexibility	736:773	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	4	96	theme	films	793:797	arg1	%					783:783	∼63.38 %	776:783	∼63.38 %	776:783	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	4	96	theme	films	793:797	arg1	morphology					702:711	Good morphology	697:711	Good morphology	697:711	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	4	97	from	morphology	702:711	arg1	flexibility					763:773	flexibility	763:773	flexibility	763:773	Good morphology, thermal stability and significant improvement in flexibility (∼63.38 %) of the films were confirmed by SEM, TGA and Mechanical test results, respectively.					
36403767	9	98	theme	present	1531:1537	arg1	work					1539:1542	the present work	1527:1542	the present work	1527:1542	Overall results of the present work proclaim that developed bio-composite film could be utilized as a biomaterial in wound care applications.					
36967163	5	0	dep	METHODS	772:778	arg1	based					794:798	based	794:798	was based on the NutriNet-Santé cohort (2009-2020)	790:839	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	5	0	dep	METHODS	772:778	arg1	included					901:908	included	901:908	were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y)	896:1010	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	9	1	theme	=	1799:1799	arg1	P-trend					1791:1797	P-trend = 0.02	1791:1804	P-trend = 0.02	1791:1804	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	10	2	theme	FODMAP	1954:1959	arg1	intake					1961:1966	FODMAP intake	1954:1966	FODMAP intake	1954:1966	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	6	3	theme	food	1108:1111	arg1	table					1125:1129	a detailed food composition table	1097:1129	a detailed food composition table	1097:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	6	4	theme	dietary	1071:1077	arg1	records					1079:1085	repeated 24-h dietary records	1057:1085	repeated 24-h dietary records linked to a detailed food composition table	1057:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	11	5	theme	experimental	2030:2041	arg1	studies					2043:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	5	6	dep	%	962:962	arg1	women					964:968	women	964:968	78.7% women	958:968	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	11	7	theme	underlying	2121:2130	arg1	mechanisms					2132:2141	the potential underlying mechanisms	2107:2141	the potential underlying mechanisms	2107:2141	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	8	8	theme	=	1528:1528	arg1	P-trend					1520:1526	P-trend = 0.04	1520:1533	P-trend = 0.04	1520:1533	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	10	9	theme	cancer	1984:1989	arg1	development					1991:2001	cancer development	1984:2001	cancer development	1984:2001	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	6	10	theme	repeated	1057:1064	arg1	records					1079:1085	repeated 24-h dietary records	1057:1085	repeated 24-h dietary records linked to a detailed food composition table	1057:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	3	11	theme	epidemiologic	517:529	arg1	study					531:535	no epidemiologic study	514:535	no epidemiologic study	514:535	However, to our knowledge, no epidemiologic study has investigated this hypothesis so far.					
36967163	5	12	theme	NutriNet-Santé	807:820	arg1	2009-2020					830:838	2009-2020	830:838	2009-2020	830:838	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	5	12	theme	NutriNet-Santé	807:820	arg1	cohort					822:827	the NutriNet-Santé cohort	803:827	the NutriNet-Santé cohort (2009-2020)	803:839	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	7	13	theme	anthropometric	1323:1336	arg1	variables					1338:1346	lifestyle, sociodemographic, and anthropometric variables	1290:1346	variables	1338:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	10	14	theme	CONCLUSIONS	1808:1818	arg1	Results					1820:1826	CONCLUSIONS Results	1808:1826	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort	1808:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	5	15	theme	±	976:976	arg1	age					981:983	mean ± SD age	971:983	mean ± SD age at baseline 42.1	971:1000	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	4	16	from	associations	626:637	arg1	cohort					764:769	a large prospective cohort	744:769	a large prospective cohort	744:769	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	4	17	theme	FODMAP	647:652	arg1	intake					654:659	FODMAP intake	647:659	FODMAP intake (total and by type)	647:679	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	0	18	theme	NutriNet-Santé	119:132	arg1	Cohort					134:139	the Prospective NutriNet-Santé Cohort	103:139	the Prospective NutriNet-Santé Cohort	103:139	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	7	19	theme	hazard	1246:1251	arg1	models					1253:1258	Cox proportional hazard models	1229:1258	Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables	1229:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	10	20	theme	large	1838:1842	arg1	study					1861:1865	this large population-based study	1833:1865	this large population-based study on French adults from the NutriNet-Santé cohort	1833:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	8	21	theme	RESULTS	1349:1355	arg1	intake					1370:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	7	22	theme	Cox	1229:1231	arg1	models					1253:1258	Cox proportional hazard models	1229:1258	Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables	1229:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	10	23	from	cohort	1908:1913	arg1	adults					1877:1882	French adults	1870:1882	French adults from the NutriNet-Santé cohort	1870:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	7	24	theme	sociodemographic	1301:1316	arg1	range					1281:1285	a large range	1273:1285	a large range of lifestyle, sociodemographic, and anthropometric variables	1273:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	8	25	theme	FODMAP	1363:1368	arg1	intake					1370:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	10	26	theme	French	1870:1875	arg1	adults					1877:1882	French adults	1870:1882	French adults from the NutriNet-Santé cohort	1870:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	1	27	theme	BACKGROUND	142:151	arg1	FODMAPs					228:234	FODMAPs	228:234	FODMAPs	228:234	BACKGROUND Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) have been shown to be involved in gastrointestinal disorders.					
36967163	1	27	theme	BACKGROUND	142:151	arg1	oligosaccharides					165:180	BACKGROUND Fermentable oligosaccharides	142:180	BACKGROUND Fermentable oligosaccharides	142:180	BACKGROUND Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) have been shown to be involved in gastrointestinal disorders.					
36967163	9	28	theme	cancer	1590:1595	arg1	risk					1597:1600	cancer risk	1590:1600	cancer risk	1590:1600	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	10	29	theme	NutriNet-Santé	1893:1906	arg1	cohort					1908:1913	the NutriNet-Santé cohort	1889:1913	the NutriNet-Santé cohort	1889:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	9	30	dep	Q5	1647:1648	arg1	1.25					1688:1691	1.25	1688:1691	1.25	1688:1691	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	30	dep	Q5	1647:1648	arg1	%					1676:1676	1.10; 95% CI: 0.97	1668:1685	1.10; 95% CI: 0.97	1668:1685	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	30	dep	Q5	1647:1648	arg1	P-trend					1694:1700	P-trend = 0.04	1694:1707	P-trend = 0.04	1694:1707	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	8	31	theme	overall	1407:1413	arg1	risk					1422:1425	increased overall cancer risk	1397:1425	increased overall cancer risk	1397:1425	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	9	32	theme	HR	1742:1743	arg1	Q5					1745:1746	HR Q5	1742:1746	HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79	1742:1788	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	10	33	theme	significant	1922:1932	arg1	association					1934:1944	a significant association	1920:1944	a significant association between FODMAP intake and the risk of cancer development	1920:2001	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	0	34	theme	Fermentable	0:10	arg1	FODMAPs					75:81	FODMAPs	75:81	FODMAPs	75:81	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	0	34	theme	Fermentable	0:10	arg1	Oligosaccharides					12:27	Fermentable Oligosaccharides	0:27	Fermentable Oligosaccharides	0:27	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	5	35	theme	mean	971:974	arg1	age					981:983	mean ± SD age	971:983	mean ± SD age at baseline 42.1	971:1000	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	7	36	theme	cancer	1199:1204	arg1	risks					1206:1210	cancer risks	1199:1210	cancer risks	1199:1210	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	2	37	theme	chronic	434:440	arg1	diseases					442:449	other chronic diseases	428:449	other chronic diseases such as cancer	428:464	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	2	37	theme	chronic	434:440	arg1	cancer					459:464	cancer	459:464	cancer	459:464	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	9	38	theme	overall	1628:1634	arg1	cancer					1636:1641	overall cancer	1628:1641	overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04)	1628:1708	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	38	theme	overall	1628:1634	arg1	Q5					1647:1648	HR Q5	1644:1648	HR Q5 compared with Q1	1644:1665	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	11	39	theme	Further	2004:2010	arg1	studies					2043:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	2	40	theme	potential	332:340	arg1	view					302:305	view	302:305	view of their proinflammatory potential	302:340	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	2	40	theme	potential	332:340	arg1	interactions					352:363	their interactions	346:363	their interactions with the gut microbiota	346:387	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	5	41	theme	follow-up	934:942	arg1	time					944:947	median follow-up time	927:947	median follow-up time = 7.7 y	927:955	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	8	42	theme	sex-specific	1460:1471	arg1	Q5					1473:1474	sex-specific Q5	1460:1474	sex-specific Q5 compared with Q1	1460:1491	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	4	43	theme	prospective	752:762	arg1	cohort					764:769	a large prospective cohort	744:769	a large prospective cohort	744:769	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	2	44	theme	gut	374:376	arg1	microbiota					378:387	the gut microbiota	370:387	the gut microbiota	370:387	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	5	45	from	baseline	887:894	arg1	participants					856:867	104,909 adult participants	842:867	104,909 adult participants without cancer at baseline	842:894	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	5	46	theme	=	949:949	arg1	time					944:947	median follow-up time	927:947	median follow-up time = 7.7 y	927:955	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	7	47	theme	FODMAP	1153:1158	arg1	intake					1160:1165	FODMAP intake	1153:1165	FODMAP intake (expressed in quintiles, Q)	1153:1193	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	9	48	dep	Q1	1762:1763	arg1	1.78					1766:1769	1.78	1766:1769	1.78	1766:1769	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	48	dep	Q1	1762:1763	arg1	%					1774:1774	95% CI: 1.13-2.79	1772:1788	Q1: 1.78; 95% CI: 1.13-2.79	1762:1788	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	8	49	dep	associated	1381:1390	arg1	n					1428:1428	n	1428:1428	n = 3374 incident cases	1428:1450	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	7	50	theme	variables	1338:1346	arg1	range					1281:1285	a large range	1273:1285	a large range of lifestyle, sociodemographic, and anthropometric variables	1273:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	6	51	theme	24-h	1066:1069	arg1	records					1079:1085	repeated 24-h dietary records	1057:1085	repeated 24-h dietary records linked to a detailed food composition table	1057:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	0	52	theme	Prospective	107:117	arg1	Cohort					134:139	the Prospective NutriNet-Santé Cohort	103:139	the Prospective NutriNet-Santé Cohort	103:139	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	9	53	dep	n	1733:1733	arg1	P-trend					1791:1797	P-trend = 0.02	1791:1804	P-trend = 0.02	1791:1804	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	53	dep	n	1733:1733	arg1	Q5					1745:1746	HR Q5	1742:1746	HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79	1742:1788	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	7	54	theme	large	1275:1279	arg1	range					1281:1285	a large range	1273:1285	a large range of lifestyle, sociodemographic, and anthropometric variables	1273:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	5	55	dep	=	949:949	arg1	y					955:955	7.7 y	951:955	7.7 y	951:955	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	6	56	attach	linked	1087:1092	arg2	records					1079:1085	repeated 24-h dietary records	1057:1085	repeated 24-h dietary records linked to a detailed food composition table	1057:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	6	56	attach	linked	1087:1092	arg1	table					1125:1129	a detailed food composition table	1097:1129	a detailed food composition table	1097:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	5	57	theme	SD	978:979	arg1	age					981:983	mean ± SD age	971:983	mean ± SD age at baseline 42.1	971:1000	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	10	58	theme	development	1991:2001	arg1	intake					1961:1966	FODMAP intake	1954:1966	FODMAP intake	1954:1966	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	10	58	theme	development	1991:2001	arg1	risk					1976:1979	the risk	1972:1979	the risk of cancer development	1972:2001	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	6	59	theme	composition	1113:1123	arg1	table					1125:1129	a detailed food composition table	1097:1129	a detailed food composition table	1097:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	9	60	theme	=	1702:1702	arg1	P-trend					1694:1700	P-trend = 0.04	1694:1707	P-trend = 0.04	1694:1707	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	5	61	theme	adult	850:854	arg1	participants					856:867	104,909 adult participants	842:867	104,909 adult participants without cancer at baseline	842:894	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	8	62	theme	Total	1357:1361	arg1	intake					1370:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake	1349:1375	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	6	63	theme	detailed	1099:1106	arg1	table					1125:1129	a detailed food composition table	1097:1129	a detailed food composition table	1097:1129	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	4	64	theme	cancer	685:690	arg1	risk					692:695	cancer risk	685:695	cancer risk (overall, breast, prostate, and colorectal)	685:739	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	7	65	theme	proportional	1233:1244	arg1	models					1253:1258	Cox proportional hazard models	1229:1258	Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables	1229:1346	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	9	66	theme	colorectal	1714:1723	arg1	cancer					1725:1730	colorectal cancer	1714:1730	colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02)	1714:1805	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	66	theme	colorectal	1714:1723	arg1	n					1733:1733	n = 272	1733:1739	n = 272	1733:1739	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	8	67	dep	n	1428:1428	arg1	1.44					1514:1517	1.44	1514:1517	1.44	1514:1517	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	8	67	dep	n	1428:1428	arg1	P-trend					1520:1526	P-trend = 0.04	1520:1533	P-trend = 0.04	1520:1533	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	8	67	dep	n	1428:1428	arg1	HR					1453:1454	HR	1453:1454	HR for sex-specific Q5 compared with Q1	1453:1491	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	8	67	dep	n	1428:1428	arg1	%					1502:1502	1.21; 95%	1494:1502	1.21; 95% CI: 1.02	1494:1511	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	1	68	theme	Fermentable	153:163	arg1	FODMAPs					228:234	FODMAPs	228:234	FODMAPs	228:234	BACKGROUND Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) have been shown to be involved in gastrointestinal disorders.					
36967163	1	68	theme	Fermentable	153:163	arg1	oligosaccharides					165:180	BACKGROUND Fermentable oligosaccharides	142:180	BACKGROUND Fermentable oligosaccharides	142:180	BACKGROUND Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) have been shown to be involved in gastrointestinal disorders.					
36967163	2	69	with	view	302:305	arg1	microbiota					378:387	the gut microbiota	370:387	the gut microbiota	370:387	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	8	70	theme	increased	1397:1405	arg1	risk					1422:1425	increased overall cancer risk	1397:1425	increased overall cancer risk	1397:1425	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	9	71	theme	=	1735:1735	arg1	cancer					1725:1730	colorectal cancer	1714:1730	colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02)	1714:1805	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	71	theme	=	1735:1735	arg1	n					1733:1733	n = 272	1733:1739	n = 272	1733:1739	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	11	72	theme	potential	2111:2119	arg1	mechanisms					2132:2141	the potential underlying mechanisms	2107:2141	the potential underlying mechanisms	2107:2141	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	0	73	theme	Cancer	88:93	arg1	Risk					95:98	Cancer Risk	88:98	Cancer Risk	88:98	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	7	74	dep	intake	1160:1165	arg1	expressed					1168:1176	expressed	1168:1176	expressed	1168:1176	Associations between FODMAP intake (expressed in quintiles, Q) and cancer risks were assessed by Cox proportional hazard models adjusted for a large range of lifestyle, sociodemographic, and anthropometric variables.					
36967163	6	75	theme	dietary	1022:1028	arg1	intakes					1030:1036	Baseline dietary intakes	1013:1036	Baseline dietary intakes	1013:1036	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	8	76	theme	cancer	1415:1420	arg1	risk					1422:1425	increased overall cancer risk	1397:1425	increased overall cancer risk	1397:1425	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	11	77	from	data	2099:2102	arg1	mechanisms					2132:2141	the potential underlying mechanisms	2107:2141	the potential underlying mechanisms	2107:2141	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	10	78	from	study	1861:1865	arg1	adults					1877:1882	French adults	1870:1882	French adults from the NutriNet-Santé cohort	1870:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	10	78	from	study	1861:1865	arg1	Results					1820:1826	CONCLUSIONS Results	1808:1826	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort	1808:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	2	79	theme	diseases	442:449	arg1	etiology					416:423	the etiology	412:423	the etiology of other chronic diseases such as cancer	412:464	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	4	80	dep	OBJECTIVES	578:587	arg1	was					603:605	was	603:605	was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort	603:769	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	5	81	from	baseline	988:995	arg1	age					981:983	mean ± SD age	971:983	mean ± SD age at baseline 42.1	971:1000	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	1	82	theme	gastrointestinal	271:286	arg1	disorders					288:296	gastrointestinal disorders	271:296	gastrointestinal disorders	271:296	BACKGROUND Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) have been shown to be involved in gastrointestinal disorders.					
36967163	4	83	dep	risk	692:695	arg1	prostate					715:722	prostate	715:722	prostate	715:722	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	4	83	dep	risk	692:695	arg1	colorectal					729:738	colorectal	729:738	colorectal	729:738	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	4	83	dep	risk	692:695	arg1	breast					707:712	breast	707:712	breast	707:712	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	2	84	theme	other	428:432	arg1	diseases					442:449	other chronic diseases	428:449	other chronic diseases such as cancer	428:464	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	2	84	theme	other	428:432	arg1	cancer					459:464	cancer	459:464	cancer	459:464	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	8	85	theme	incident	1437:1444	arg1	cases					1446:1450	3374 incident cases	1432:1450	3374 incident cases	1432:1450	RESULTS Total FODMAP intake was associated with increased overall cancer risk (n = 3374 incident cases, HR for sex-specific Q5 compared with Q1: 1.21; 95% CI: 1.02, 1.44; P-trend = 0.04).					
36967163	5	86	dep	±	1002:1002	arg1	time					944:947	median follow-up time	927:947	median follow-up time = 7.7 y	927:955	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	5	86	dep	±	1002:1002	arg1	%					962:962	78.7%	958:962	78.7% women	958:968	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	6	87	theme	Baseline	1013:1020	arg1	intakes					1030:1036	Baseline dietary intakes	1013:1036	Baseline dietary intakes	1013:1036	Baseline dietary intakes were obtained from repeated 24-h dietary records linked to a detailed food composition table.					
36967163	9	88	theme	HR	1644:1645	arg1	cancer					1636:1641	overall cancer	1628:1641	overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04)	1628:1708	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	9	88	theme	HR	1644:1645	arg1	Q5					1647:1648	HR Q5	1644:1648	HR Q5 compared with Q1	1644:1665	In particular, oligosaccharides were associated with cancer risk: a trend was observed for overall cancer (HR Q5 compared with Q1: 1.10; 95% CI: 0.97, 1.25; P-trend = 0.04) and colorectal cancer (n = 272, HR Q5 compared with Q1: 1.78; 95% CI: 1.13-2.79; P-trend = 0.02).					
36967163	4	89	dep	intake	654:659	arg1	total					662:666	total	662:666	total	662:666	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	4	89	dep	intake	654:659	arg1	type					675:678	type	675:678	type	675:678	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
36967163	2	90	with	interactions	352:363	arg1	microbiota					378:387	the gut microbiota	370:387	the gut microbiota	370:387	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	5	91	theme	median	927:932	arg1	time					944:947	median follow-up time	927:947	median follow-up time = 7.7 y	927:955	METHODS The study was based on the NutriNet-Santé cohort (2009-2020); 104,909 adult participants without cancer at baseline were included in our analyses (median follow-up time = 7.7 y, 78.7% women, mean ± SD age at baseline 42.1 ± 14.5 y).					
36967163	11	92	theme	epidemiologic	2012:2024	arg1	studies					2043:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies	2004:2049	Further epidemiologic and experimental studies are needed to confirm these results and provide data on the potential underlying mechanisms.					
36967163	10	93	theme	population-based	1844:1859	arg1	study					1861:1865	this large population-based study	1833:1865	this large population-based study on French adults from the NutriNet-Santé cohort	1833:1913	CONCLUSIONS Results from this large population-based study on French adults from the NutriNet-Santé cohort show a significant association between FODMAP intake and the risk of cancer development.					
36967163	2	94	theme	proinflammatory	316:330	arg1	potential					332:340	their proinflammatory potential	310:340	their proinflammatory potential	310:340	In view of their proinflammatory potential and their interactions with the gut microbiota, their contribution to the etiology of other chronic diseases such as cancer has been postulated.					
36967163	0	95	dep	Oligosaccharides	12:27	arg1	Cohort					134:139	the Prospective NutriNet-Santé Cohort	103:139	the Prospective NutriNet-Santé Cohort	103:139	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Cancer Risk in the Prospective NutriNet-Santé Cohort.					
36967163	4	96	theme	large	746:750	arg1	cohort					764:769	a large prospective cohort	744:769	a large prospective cohort	744:769	OBJECTIVES Our objective was to investigate the associations between FODMAP intake (total and by type) and cancer risk (overall, breast, prostate, and colorectal) in a large prospective cohort.					
35413301	0	0	theme	acid-co-itaconic	99:114	arg1	cellulose-grafted-poly					68:89	carboxymethyl cellulose-grafted-poly	54:89	carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	54:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	0	0	theme	acid-co-itaconic	99:114	arg1	acid					116:119	acrylic acid-co-itaconic acid	91:119	acrylic acid-co-itaconic acid	91:119	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	8	1	theme	AA-co-IA	1562:1569	arg1	adsorbent					1613:1621	adsorbent	1613:1621	adsorbent	1613:1621	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	8	1	theme	AA-co-IA	1562:1569	arg1	/MMT					1571:1574	CMC-g-poly (AA-co-IA)/MMT	1550:1574	CMC-g-poly (AA-co-IA)/MMT	1550:1574	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	7	2	theme	ad	1411:1412	arg1	behavior					1427:1434	ad (de)sorption behavior	1411:1434	ad (de)sorption behavior study	1411:1440	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	0	3	theme	acrylic	91:97	arg1	cellulose-grafted-poly					68:89	carboxymethyl cellulose-grafted-poly	54:89	carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	54:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	0	3	theme	acrylic	91:97	arg1	acid					116:119	acrylic acid-co-itaconic acid	91:119	acrylic acid-co-itaconic acid	91:119	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	5	4	theme	Langmuir	1065:1072	arg1	models					1261:1266	the best-fitted models	1245:1266	the best-fitted models for kinetic and equilibrium data	1245:1299	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	5	4	theme	Langmuir	1065:1072	arg1	models					1074:1079	Pseudo-second-order and Langmuir models	1041:1079	models	1074:1079	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	4	5	theme	/MMT	814:817	arg1	efficiency					779:788	The maximum removal efficiency	759:788	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	759:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	6	theme	response	976:983	arg1	RSM-CCD					1031:1037	RSM-CCD	1031:1037	RSM-CCD	1031:1037	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	6	theme	response	976:983	arg1	design					1023:1028	a response surface methodology-central composite design	974:1028	a response surface methodology-central composite design (RSM-CCD)	974:1038	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	5	7	theme	19.1205 mg/g	1150:1161	arg1	capacity					1121:1128	the maximum monolayer adsorption capacity	1088:1128	the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1088:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	2	8	theme	nano-sheets	521:531	arg1	incorporation					483:495	incorporation	483:495	incorporation of montmorillonite clay nano-sheets (MMT)	483:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	2	8	theme	nano-sheets	521:531	arg1	ratio					463:467	IA/AA molar ratio	451:467	IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT)	451:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	7	9	theme	sorption	1418:1425	arg1	behavior					1427:1434	ad (de)sorption behavior	1411:1434	ad (de)sorption behavior study	1411:1440	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	8	10	from	wastewater	1651:1660	arg1	removal					1638:1644	safranin-O removal	1627:1644	safranin-O removal from wastewater	1627:1660	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	5	11	theme	maximum	1092:1098	arg1	capacity					1121:1128	the maximum monolayer adsorption capacity	1088:1128	the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1088:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	2	12	theme	clay	516:519	arg1	MMT					534:536	MMT	534:536	MMT	534:536	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	2	12	theme	clay	516:519	arg1	nano-sheets					521:531	montmorillonite clay nano-sheets	500:531	montmorillonite clay nano-sheets (MMT)	500:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	4	13	theme	optimum	825:831	arg1	conditions					833:842	optimum conditions	825:842	optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	825:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	5	14	theme	CMC-g-poly	1167:1176	arg1	samples					1219:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	2	15	theme	montmorillonite	500:514	arg1	MMT					534:536	MMT	534:536	MMT	534:536	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	2	15	theme	montmorillonite	500:514	arg1	nano-sheets					521:531	montmorillonite clay nano-sheets	500:531	montmorillonite clay nano-sheets (MMT)	500:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	7	16	theme	de	1415:1416	arg1	behavior					1427:1434	ad (de)sorption behavior	1411:1434	ad (de)sorption behavior study	1411:1440	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	1	17	theme	acid	190:193	arg1	Copolymer					146:154	Copolymer	146:154	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA))	146:275	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	17	theme	acid	190:193	arg1	adsorbent					312:320	adsorbent	312:320	adsorbent	312:320	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	8	18	theme	CMC-g-poly	1550:1559	arg1	adsorbent					1613:1621	adsorbent	1613:1621	adsorbent	1613:1621	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	8	18	theme	CMC-g-poly	1550:1559	arg1	/MMT					1571:1574	CMC-g-poly (AA-co-IA)/MMT	1550:1574	CMC-g-poly (AA-co-IA)/MMT	1550:1574	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	0	19	from	wastewater	37:46	arg1	removal					24:30	Safranin-O cationic dye removal	0:30	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	0:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	4	20	theme	CMC-g-poly	793:802	arg1	/MMT					814:817	CMC-g-poly (AA-co-IA)/MMT	793:817	CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	793:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	21	theme	40 min	938:943	arg1	pH					850:851	pH	850:851	pH of 8	850:856	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	21	theme	40 min	938:943	arg1	time					930:933	contact time	922:933	contact time of 40 min	922:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	21	theme	40 min	938:943	arg1	dose					903:906	adsorbent dose	893:906	adsorbent dose of 2 g/L	893:915	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	21	theme	40 min	938:943	arg1	concentration					867:879	initial concentration	859:879	initial concentration of 10 mg/L	859:890	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	1	22	theme	itaconic	181:188	arg1	acid					190:193	itaconic acid	181:193	itaconic acid (IA)	181:198	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	22	theme	itaconic	181:188	arg1	IA					196:197	IA	196:197	IA	196:197	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	0	23	theme	cationic	11:18	arg1	removal					24:30	Safranin-O cationic dye removal	0:30	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	0:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	4	24	theme	2 g/L	911:915	arg1	pH					850:851	pH	850:851	pH of 8	850:856	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	24	theme	2 g/L	911:915	arg1	time					930:933	contact time	922:933	contact time of 40 min	922:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	24	theme	2 g/L	911:915	arg1	dose					903:906	adsorbent dose	893:906	adsorbent dose of 2 g/L	893:915	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	24	theme	2 g/L	911:915	arg1	concentration					867:879	initial concentration	859:879	initial concentration of 10 mg/L	859:890	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	25	theme	10 mg/L	884:890	arg1	pH					850:851	pH	850:851	pH of 8	850:856	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	25	theme	10 mg/L	884:890	arg1	time					930:933	contact time	922:933	contact time of 40 min	922:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	25	theme	10 mg/L	884:890	arg1	dose					903:906	adsorbent dose	893:906	adsorbent dose of 2 g/L	893:915	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	25	theme	10 mg/L	884:890	arg1	concentration					867:879	initial concentration	859:879	initial concentration of 10 mg/L	859:890	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	5	26	theme	equilibrium	1284:1294	arg1	data					1296:1299	equilibrium data	1284:1299	equilibrium data	1284:1299	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	2	27	theme	removal	377:383	arg1	efficiencies					385:396	The swelling and removal efficiencies	360:396	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA)	360:421	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	0	28	theme	Safranin-O	0:9	arg1	removal					24:30	Safranin-O cationic dye removal	0:30	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	0:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	5	29	theme	adsorption	1110:1119	arg1	capacity					1121:1128	the maximum monolayer adsorption capacity	1088:1128	the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1088:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	4	30	theme	AA-co-IA	805:812	arg1	/MMT					814:817	CMC-g-poly (AA-co-IA)/MMT	793:817	CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	793:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	3	31	theme	MMT	707:709	arg1	nano-sheets					711:721	MMT nano-sheets	707:721	MMT nano-sheets	707:721	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	6	32	theme	safranin-O	1321:1330	arg1	decontamination					1332:1346	safranin-O decontamination	1321:1346	safranin-O decontamination	1321:1346	Thermodynamically, safranin-O decontamination was spontaneous, exothermic, and entropy decreasing.					
35413301	4	33	theme	removal	771:777	arg1	efficiency					779:788	The maximum removal efficiency	759:788	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	759:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	0	34	theme	dye	20:22	arg1	removal					24:30	Safranin-O cationic dye removal	0:30	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	0:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	4	35	theme	8	856:856	arg1	pH					850:851	pH	850:851	pH of 8	850:856	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	35	theme	8	856:856	arg1	time					930:933	contact time	922:933	contact time of 40 min	922:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	35	theme	8	856:856	arg1	dose					903:906	adsorbent dose	893:906	adsorbent dose of 2 g/L	893:915	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	35	theme	8	856:856	arg1	concentration					867:879	initial concentration	859:879	initial concentration of 10 mg/L	859:890	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	3	36	theme	AA-co-IA	604:611	arg1	samples					614:620	CMC-g-poly (AA-co-IA) samples	592:620	CMC-g-poly (AA-co-IA) samples	592:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	37	theme	surface	544:550	arg1	15.632					626:631	15.632	626:631	15.632	626:631	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	37	theme	surface	544:550	arg1	area					552:555	The surface area	540:555	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples	540:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	5	38	theme	best-fitted	1249:1259	arg1	models					1261:1266	the best-fitted models	1245:1266	the best-fitted models for kinetic and equilibrium data	1245:1299	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	5	38	theme	best-fitted	1249:1259	arg1	models					1074:1079	Pseudo-second-order and Langmuir models	1041:1079	models	1074:1079	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	1	39	theme	acid	167:170	arg1	Copolymer					146:154	Copolymer	146:154	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA))	146:275	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	39	theme	acid	167:170	arg1	adsorbent					312:320	adsorbent	312:320	adsorbent	312:320	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	4	40	theme	contact	922:928	arg1	time					930:933	contact time	922:933	contact time of 40 min	922:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	5	41	theme	18.5185 mg/g	1133:1144	arg1	capacity					1121:1128	the maximum monolayer adsorption capacity	1088:1128	the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1088:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	7	42	theme	/MMT	1475:1478	arg1	performance					1480:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	8	43	theme	safranin-O	1627:1636	arg1	removal					1638:1644	safranin-O removal	1627:1644	safranin-O removal from wastewater	1627:1660	Therefore, CMC-g-poly (AA-co-IA)/MMT was considered as a highly potential adsorbent for safranin-O removal from wastewater.					
35413301	3	44	theme	CMC-g-poly	565:574	arg1	15.632					626:631	15.632	626:631	15.632	626:631	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	44	theme	CMC-g-poly	565:574	arg1	area					552:555	The surface area	540:555	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples	540:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	5	45	theme	/MMT	1214:1217	arg1	samples					1219:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	4	46	theme	initial	859:865	arg1	concentration					867:879	initial concentration	859:879	initial concentration of 10 mg/L	859:890	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	3	47	theme	CMC-g-poly	592:601	arg1	samples					614:620	CMC-g-poly (AA-co-IA) samples	592:620	CMC-g-poly (AA-co-IA) samples	592:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	48	theme	surface	745:751	arg1	area					753:756	hydrogel surface area	736:756	hydrogel surface area	736:756	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	2	49	theme	CMC-g-poly	401:410	arg1	efficiencies					385:396	The swelling and removal efficiencies	360:396	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA)	360:421	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	0	50	theme	carboxymethyl	54:66	arg1	cellulose-grafted-poly					68:89	carboxymethyl cellulose-grafted-poly	54:89	carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid)	54:120	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	0	50	theme	carboxymethyl	54:66	arg1	acid					116:119	acrylic acid-co-itaconic acid	91:119	acrylic acid-co-itaconic acid	91:119	Safranin-O cationic dye removal from wastewater using carboxymethyl cellulose-grafted-poly(acrylic acid-co-itaconic acid) nanocomposite hydrogel.					
35413301	3	51	theme	hydrogel	736:743	arg1	area					753:756	hydrogel surface area	736:756	hydrogel surface area	736:756	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	4	52	dep	pH	850:851	arg1	i.e.					844:847	i.e.	844:847	i.e.	844:847	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	3	53	theme	MMT	560:562	arg1	15.632					626:631	15.632	626:631	15.632	626:631	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	53	theme	MMT	560:562	arg1	area					552:555	The surface area	540:555	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples	540:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	2	54	theme	IA/AA	451:455	arg1	ratio					463:467	IA/AA molar ratio	451:467	IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT)	451:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	3	55	theme	nano-sheets	711:721	arg1	effectiveness					690:702	the effectiveness	686:702	the effectiveness of MMT nano-sheets in improving hydrogel surface area	686:756	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	7	56	theme	behavior	1427:1434	arg1	study					1436:1440	ad (de)sorption behavior study	1411:1440	ad (de)sorption behavior study	1411:1440	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	7	57	theme	CMC-g-poly	1454:1463	arg1	performance					1480:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	7	58	theme	AA-co-IA	1466:1473	arg1	performance					1480:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	CMC-g-poly (AA-co-IA)/MMT performance	1454:1490	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	4	59	theme	methodology-central	993:1011	arg1	RSM-CCD					1031:1037	RSM-CCD	1031:1037	RSM-CCD	1031:1037	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	59	theme	methodology-central	993:1011	arg1	design					1023:1028	a response surface methodology-central composite design	974:1028	a response surface methodology-central composite design (RSM-CCD)	974:1038	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	5	60	theme	monolayer	1100:1108	arg1	capacity					1121:1128	the maximum monolayer adsorption capacity	1088:1128	the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1088:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	7	61	theme	multiple	1514:1521	arg1	steps					1532:1536	multiple recovery steps	1514:1536	multiple recovery steps	1514:1536	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	5	62	dep	CMC-g-poly	1167:1176	arg1	AA-co-IA					1205:1212	AA-co-IA	1205:1212	AA-co-IA	1205:1212	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	5	62	dep	CMC-g-poly	1167:1176	arg1	AA-co-IA					1179:1186	AA-co-IA	1179:1186	AA-co-IA	1179:1186	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	4	63	theme	maximum	763:769	arg1	efficiency					779:788	The maximum removal efficiency	759:788	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min	759:943	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	64	theme	surface	985:991	arg1	RSM-CCD					1031:1037	RSM-CCD	1031:1037	RSM-CCD	1031:1037	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	64	theme	surface	985:991	arg1	design					1023:1028	a response surface methodology-central composite design	974:1028	a response surface methodology-central composite design (RSM-CCD)	974:1038	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	1	65	theme	sodium	213:218	arg1	CMC-g-poly					254:263	CMC-g-poly	254:263	CMC-g-poly (AA-co-IA)	254:274	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	65	theme	sodium	213:218	arg1	hydrogel					244:251	sodium carboxymethyl cellulose hydrogel	213:251	sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA))	213:275	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	3	66	theme	samples	614:620	arg1	15.632					626:631	15.632	626:631	15.632	626:631	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	3	66	theme	samples	614:620	arg1	area					552:555	The surface area	540:555	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples	540:620	The surface area of MMT, CMC-g-poly (AA-co-IA), and CMC-g-poly (AA-co-IA) samples was 15.632, 0.61452, and 0.66584 m2/g, respectively, indicating the effectiveness of MMT nano-sheets in improving hydrogel surface area.					
35413301	1	67	theme	acrylic	159:165	arg1	AA					173:174	AA	173:174	AA	173:174	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	67	theme	acrylic	159:165	arg1	acid					167:170	acrylic acid	159:170	acrylic acid (AA)	159:175	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	68	theme	carboxymethyl	220:232	arg1	CMC-g-poly					254:263	CMC-g-poly	254:263	CMC-g-poly (AA-co-IA)	254:274	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	68	theme	carboxymethyl	220:232	arg1	hydrogel					244:251	sodium carboxymethyl cellulose hydrogel	213:251	sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA))	213:275	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	2	69	theme	swelling	364:371	arg1	efficiencies					385:396	The swelling and removal efficiencies	360:396	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA)	360:421	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	4	70	theme	composite	1013:1021	arg1	RSM-CCD					1031:1037	RSM-CCD	1031:1037	RSM-CCD	1031:1037	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	4	70	theme	composite	1013:1021	arg1	design					1023:1028	a response surface methodology-central composite design	974:1028	a response surface methodology-central composite design (RSM-CCD)	974:1038	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
35413301	1	71	theme	cellulose	234:242	arg1	CMC-g-poly					254:263	CMC-g-poly	254:263	CMC-g-poly (AA-co-IA)	254:274	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	1	71	theme	cellulose	234:242	arg1	hydrogel					244:251	sodium carboxymethyl cellulose hydrogel	213:251	sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA))	213:275	Copolymer of acrylic acid (AA) and itaconic acid (IA) grafted onto sodium carboxymethyl cellulose hydrogel (CMC-g-poly (AA-co-IA)) was successfully synthesized as an adsorbent to remove safranin-O from wastewater.					
35413301	2	72	theme	molar	457:461	arg1	ratio					463:467	IA/AA molar ratio	451:467	IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT)	451:537	The swelling and removal efficiencies of CMC-g-poly (AA-co-IA) were enhanced by increasing IA/AA molar ratio as well as by incorporation of montmorillonite clay nano-sheets (MMT).					
35413301	5	73	theme	Pseudo-second-order	1041:1059	arg1	models					1261:1266	the best-fitted models	1245:1266	the best-fitted models for kinetic and equilibrium data	1245:1299	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	5	73	theme	Pseudo-second-order	1041:1059	arg1	models					1074:1079	Pseudo-second-order and Langmuir models	1041:1079	models	1074:1079	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	7	74	theme	recovery	1523:1530	arg1	steps					1532:1536	multiple recovery steps	1514:1536	multiple recovery steps	1514:1536	Moreover, ad (de)sorption behavior study showed that CMC-g-poly (AA-co-IA)/MMT performance was not changed after multiple recovery steps.					
35413301	5	75	theme	CMC-g-poly	1193:1202	arg1	samples					1219:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples	1167:1225	Pseudo-second-order and Langmuir models giving the maximum monolayer adsorption capacity of 18.5185 mg/g and 19.1205 mg/g for CMC-g-poly (AA-co-IA) and CMC-g-poly (AA-co-IA)/MMT samples, respectively are the best-fitted models for kinetic and equilibrium data.					
35413301	4	76	theme	adsorbent	893:901	arg1	dose					903:906	adsorbent dose	893:906	adsorbent dose of 2 g/L	893:915	The maximum removal efficiency of CMC-g-poly (AA-co-IA)/MMT under optimum conditions i.e., pH of 8, initial concentration of 10 mg/L, adsorbent dose of 2 g/L, and contact time of 40 min was ascertained 99.78% using a response surface methodology-central composite design (RSM-CCD).					
37050003	1	0	theme	antibacterial	180:192	arg1	properties					194:203	their unique antibacterial properties	167:203	their unique antibacterial properties	167:203	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	7	1	contain	contained	1061:1069	arg1	hydrogel					1047:1054	a hydrogel	1045:1054	a hydrogel that contained silver nanoparticles	1045:1090	It can be said that microwave irradiation was successful in creating a hydrogel that contained silver nanoparticles.					
37050003	7	1	contain	contained	1061:1069	arg2	nanoparticles					1078:1090	silver nanoparticles	1071:1090	silver nanoparticles	1071:1090	It can be said that microwave irradiation was successful in creating a hydrogel that contained silver nanoparticles.					
37050003	6	2	theme	diffusion	958:966	arg1	method					968:973	the agar diffusion method	949:973	the agar diffusion method	949:973	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	7	3	theme	silver	1071:1076	arg1	nanoparticles					1078:1090	silver nanoparticles	1071:1090	silver nanoparticles	1071:1090	It can be said that microwave irradiation was successful in creating a hydrogel that contained silver nanoparticles.					
37050003	6	4	theme	agar	953:956	arg1	method					968:973	the agar diffusion method	949:973	the agar diffusion method	949:973	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	3	5	theme	microwave	368:376	arg1	irradiation					378:388	microwave irradiation	368:388	microwave irradiation	368:388	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	4	6	theme	spectrum	582:589	arg1	analyses					591:598	FT-IR spectrum analyses	576:598	FT-IR spectrum analyses	576:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	5	7	dep	in	773:774	arg1	vivo					776:779	vivo	776:779	vivo	776:779	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	3	8	theme	hydrogel	479:486	arg1	samples					488:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	3	9	theme	samples	488:494	arg1	preparation					412:422	the preparation	408:422	the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	408:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	4	10	theme	FT-IR	576:580	arg1	analyses					591:598	FT-IR spectrum analyses	576:598	FT-IR spectrum analyses	576:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	1	11	theme	Silver	91:96	arg1	composites					111:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	3	12	theme	grafted	447:453	arg1	samples					488:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	6	13	theme	polyvinyl	834:842	arg1	alcohol					844:850	chitosan-grafted polyvinyl alcohol	817:850	chitosan-grafted polyvinyl alcohol	817:850	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	1	14	theme	nanoparticle	98:109	arg1	composites					111:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	7	15	theme	microwave	996:1004	arg1	irradiation					1006:1016	microwave irradiation	996:1016	microwave irradiation	996:1016	It can be said that microwave irradiation was successful in creating a hydrogel that contained silver nanoparticles.					
37050003	0	16	theme	Silver	0:5	arg1	Nanoparticles					7:19	Silver Nanoparticles	0:19	Silver Nanoparticles	0:19	Silver Nanoparticles Loaded on Chitosan-g-PVA Hydrogel for the Wound-Healing Applications.					
37050003	4	17	theme	UV-spectrum	554:564	arg1	release					608:614	the release	604:614	the release of silver ions	604:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	17	theme	UV-spectrum	554:564	arg1	accomplishment					512:525	the accomplishment	508:525	the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses	508:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	6	18	theme	antibacterial	890:902	arg1	activity					904:911	excellent antibacterial activity	880:911	excellent antibacterial activity against E. coli and S. aureus	880:941	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	3	19	theme	Ch	443:444	arg1	samples					488:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	4	20	theme	silver	619:624	arg1	ions					626:629	silver ions	619:629	silver ions	619:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	21	theme	TEM	567:569	arg1	release					608:614	the release	604:614	the release of silver ions	604:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	21	theme	TEM	567:569	arg1	accomplishment					512:525	the accomplishment	508:525	the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses	508:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	5	22	theme	prepared	685:692	arg1	samples					703:709	the prepared hydrogel samples	681:709	the prepared hydrogel samples	681:709	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	2	23	theme	current	213:219	arg1	work					221:224	the current work	209:224	the current work	209:224	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	1	24	theme	abundant	127:134	arg1	applications					147:158	abundant biomedical applications	127:158	abundant biomedical applications	127:158	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	5	25	theme	fibroblast	747:756	arg1	in					737:738	in	737:738	in	737:738	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	5	25	theme	fibroblast	747:756	arg1	cells					758:762	fibroblast cells	747:762	fibroblast cells	747:762	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	5	26	theme	hydrogel	694:701	arg1	samples					703:709	the prepared hydrogel samples	681:709	the prepared hydrogel samples	681:709	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	5	27	theme	samples	703:709	arg1	ability					670:676	The wound-healing ability	652:676	The wound-healing ability of the prepared hydrogel samples	652:709	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	2	28	used	used	254:257	arg2	agent					281:285	a natural reducing agent	262:285	a natural reducing agent	262:285	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	28	used	used	254:257	arg2	extract					242:248	green tea leaf extract	227:248	green tea leaf extract	227:248	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	3	29	theme	polyvinyl	455:463	arg1	alcohol					465:471	polyvinyl alcohol	455:471	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	3	29	theme	polyvinyl	455:463	arg1	PVA					474:476	PVA	474:476	PVA	474:476	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	0	30	theme	Chitosan-g-PVA	31:44	arg1	Hydrogel					46:53	Chitosan-g-PVA Hydrogel	31:53	Chitosan-g-PVA Hydrogel for the Wound-Healing Applications	31:88	Silver Nanoparticles Loaded on Chitosan-g-PVA Hydrogel for the Wound-Healing Applications.					
37050003	4	31	theme	AgNPs	530:534	arg1	polymer					545:551	AgNPs hydrogel polymer	530:551	AgNPs hydrogel polymer	530:551	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	3	32	theme	AgNPs/chitosan	427:440	arg1	samples					488:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	3	33	theme	alcohol	465:471	arg1	samples					488:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples	427:494	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	1	34	contain	have	122:125	arg1	composites					111:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites	91:120	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	1	34	contain	have	122:125	arg2	applications					147:158	abundant biomedical applications	127:158	abundant biomedical applications	127:158	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	6	35	theme	chitosan-grafted	817:832	arg1	alcohol					844:850	chitosan-grafted polyvinyl alcohol	817:850	chitosan-grafted polyvinyl alcohol	817:850	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	1	36	theme	biomedical	136:145	arg1	applications					147:158	abundant biomedical applications	127:158	abundant biomedical applications	127:158	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
37050003	3	37	used	used	399:402	arg2	irradiation					378:388	microwave irradiation	368:388	microwave irradiation	368:388	Furthermore, microwave irradiation has been used for the preparation of AgNPs/chitosan (Ch) grafted polyvinyl alcohol (PVA) hydrogel samples.					
37050003	4	38	theme	polymer	545:551	arg1	release					608:614	the release	604:614	the release of silver ions	604:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	38	theme	polymer	545:551	arg1	accomplishment					512:525	the accomplishment	508:525	the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses	508:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	5	39	theme	wound-healing	656:668	arg1	ability					670:676	The wound-healing ability	652:676	The wound-healing ability of the prepared hydrogel samples	652:709	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	2	40	theme	tea	233:235	arg1	agent					281:285	a natural reducing agent	262:285	a natural reducing agent	262:285	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	40	theme	tea	233:235	arg1	extract					242:248	green tea leaf extract	227:248	green tea leaf extract	227:248	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	41	theme	leaf	237:240	arg1	agent					281:285	a natural reducing agent	262:285	a natural reducing agent	262:285	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	41	theme	leaf	237:240	arg1	extract					242:248	green tea leaf extract	227:248	green tea leaf extract	227:248	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	5	42	dep	in	737:738	arg1	vitro					740:744	vitro	740:744	vitro	740:744	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	5	42	dep	in	737:738	arg1	the					733:735	the	733:735	the	733:735	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	4	43	theme	hydrogel	536:543	arg1	polymer					545:551	AgNPs hydrogel polymer	530:551	AgNPs hydrogel polymer	530:551	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	2	44	theme	reducing	272:279	arg1	agent					281:285	a natural reducing agent	262:285	a natural reducing agent	262:285	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	44	theme	reducing	272:279	arg1	extract					242:248	green tea leaf extract	227:248	green tea leaf extract	227:248	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	45	theme	irradiation	331:341	arg1	technology					343:352	microwave irradiation technology	321:352	microwave irradiation technology	321:352	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	46	theme	natural	264:270	arg1	agent					281:285	a natural reducing agent	262:285	a natural reducing agent	262:285	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	46	theme	natural	264:270	arg1	extract					242:248	green tea leaf extract	227:248	green tea leaf extract	227:248	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	2	47	theme	microwave	321:329	arg1	irradiation					331:341	microwave irradiation	321:341	microwave irradiation technology	321:352	In the current work, green tea leaf extract was used as a natural reducing agent to synthesize AgNPs (AgNPs) using microwave irradiation technology.					
37050003	4	48	theme	analyses	591:598	arg1	release					608:614	the release	604:614	the release of silver ions	604:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	48	theme	analyses	591:598	arg1	accomplishment					512:525	the accomplishment	508:525	the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses	508:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	49	theme	ions	626:629	arg1	release					608:614	the release	604:614	the release of silver ions	604:629	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	4	49	theme	ions	626:629	arg1	accomplishment					512:525	the accomplishment	508:525	the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses	508:598	To approve the accomplishment of AgNPs hydrogel polymer, UV-spectrum, TEM, and FT-IR spectrum analyses and the release of silver ions, actions were taken.					
37050003	5	50	theme	rat	787:789	arg1	models					791:796	rat models	787:796	rat models	787:796	The wound-healing ability of the prepared hydrogel samples was measured via both the in vitro (fibroblast cells) and the in vivo using rat models.					
37050003	0	51	theme	Wound-Healing	63:75	arg1	Applications					77:88	the Wound-Healing Applications	59:88	the Wound-Healing Applications	59:88	Silver Nanoparticles Loaded on Chitosan-g-PVA Hydrogel for the Wound-Healing Applications.					
37050003	6	52	theme	excellent	880:888	arg1	activity					904:911	excellent antibacterial activity	880:911	excellent antibacterial activity against E. coli and S. aureus	880:941	It was found that chitosan-grafted polyvinyl alcohol, including AgNPs, exhibited excellent antibacterial activity against E. coli and S. aureus using the agar diffusion method.					
37050003	1	53	theme	unique	173:178	arg1	properties					194:203	their unique antibacterial properties	167:203	their unique antibacterial properties	167:203	Silver nanoparticle composites have abundant biomedical applications due to their unique antibacterial properties.					
36278431	8	0	theme	co-deliver	1150:1159	arg1	combinations					1161:1172	co-deliver combinations	1150:1172	co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals	1150:1290	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	4	1	theme	composite	635:643	arg1	nanoparticles					645:657	the composite nanoparticles	631:657	the composite nanoparticles	631:657	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	8	2	theme	supplements	1259:1269	arg1	development					1226:1236	the development	1222:1236	the development of functional foods, supplements, and pharmaceuticals	1222:1290	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	1	3	theme	specific	184:191	arg1	nutrients					193:201	specific nutrients	184:201	specific nutrients	184:201	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	8	4	theme	pharmaceuticals	1276:1290	arg1	development					1226:1236	the development	1222:1236	the development of functional foods, supplements, and pharmaceuticals	1222:1290	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	0	5	from	Co-encapsulation	0:15	arg1	nanoparticles					78:90	zein/carboxymethyl cellulose nanoparticles	49:90	zein/carboxymethyl cellulose nanoparticles	49:90	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	7	6	theme	resveratrol	1053:1063	arg1	bioaccessibility					1015:1030	the in vitro bioaccessibility	1002:1030	the in vitro bioaccessibility of the quercetin and resveratrol	1002:1063	Moreover, encapsulation increased the in vitro bioaccessibility of the quercetin and resveratrol.					
36278431	6	7	theme	gastrointestinal	892:907	arg1	conditions					909:918	simulated gastrointestinal conditions	882:918	simulated gastrointestinal conditions	882:918	Encapsulation of the nutraceuticals was shown to delay their release under simulated gastrointestinal conditions, which may be beneficial for some applications.					
36278431	0	8	dep	in	125:126	arg1	vitro					128:132	vitro	128:132	vitro	128:132	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	3	9	theme	cellulose	427:435	arg1	nanoparticles					437:449	Zein/carboxymethyl cellulose nanoparticles	408:449	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm)	408:483	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	8	10	theme	compounds	1187:1195	arg1	combinations					1161:1172	co-deliver combinations	1150:1172	co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals	1150:1290	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	6	11	theme	simulated	882:890	arg1	conditions					909:918	simulated gastrointestinal conditions	882:918	simulated gastrointestinal conditions	882:918	Encapsulation of the nutraceuticals was shown to delay their release under simulated gastrointestinal conditions, which may be beneficial for some applications.					
36278431	2	12	theme	composite	316:324	arg1	nanoparticles					326:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	In this work, zein/carboxymethyl cellulose composite nanoparticles were successfully prepared using antisolvent precipitation methods.					
36278431	1	13	theme	nutrients	193:201	arg1	combinations					168:179	combinations	168:179	combinations of specific nutrients and nutraceuticals	168:220	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	0	14	theme	in	125:126	arg1	digestion					134:142	in vitro digestion	125:142	in vitro digestion	125:142	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	8	15	theme	bioactive	1177:1185	arg1	compounds					1187:1195	bioactive compounds	1177:1195	bioactive compounds	1177:1195	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	7	16	theme	quercetin	1039:1047	arg1	bioaccessibility					1015:1030	the in vitro bioaccessibility	1002:1030	the in vitro bioaccessibility of the quercetin and resveratrol	1002:1063	Moreover, encapsulation increased the in vitro bioaccessibility of the quercetin and resveratrol.					
36278431	2	17	theme	cellulose	306:314	arg1	nanoparticles					326:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	In this work, zein/carboxymethyl cellulose composite nanoparticles were successfully prepared using antisolvent precipitation methods.					
36278431	2	18	theme	antisolvent	373:383	arg1	methods					399:405	antisolvent precipitation methods	373:405	antisolvent precipitation methods	373:405	In this work, zein/carboxymethyl cellulose composite nanoparticles were successfully prepared using antisolvent precipitation methods.					
36278431	1	19	theme	nutraceuticals	207:220	arg1	combinations					168:179	combinations	168:179	combinations of specific nutrients and nutraceuticals	168:220	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	3	20	theme	smallest	460:467	arg1	size					469:472	the smallest size	456:472	the smallest size (204.6 nm)	456:483	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	3	20	theme	smallest	460:467	arg1	nm					481:482	204.6 nm	475:482	204.6 nm	475:482	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	4	21	theme	binding	603:609	arg1	forces					611:616	dominant binding forces	594:616	dominant binding forces	594:616	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	8	22	theme	zein/carboxymethyl	1092:1109	arg1	nanoparticles					1121:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	7	23	dep	in	1006:1007	arg1	vitro					1009:1013	vitro	1009:1013	vitro	1009:1013	Moreover, encapsulation increased the in vitro bioaccessibility of the quercetin and resveratrol.					
36278431	8	24	used	used	1142:1145	arg2	nanoparticles					1121:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	0	25	theme	quercetin	20:28	arg1	Co-encapsulation					0:15	Co-encapsulation	0:15	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.	0:143	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	1	26	theme	synergistic	234:244	arg1	benefits					253:260	synergistic health benefits	234:260	synergistic health benefits to humans	234:270	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	5	27	theme	thermal	786:792	arg1	degradation					794:804	thermal degradation	786:804	thermal degradation	786:804	Quercetin and resveratrol were then encapsulated within these nanocarriers, which improved their resistance to both light and thermal degradation.					
36278431	1	28	theme	health	246:251	arg1	benefits					253:260	synergistic health benefits	234:260	synergistic health benefits to humans	234:270	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	3	29	theme	mass	506:509	arg1	ratio					511:515	the mass ratio	502:515	the mass ratio of zein to CMC	502:530	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	3	29	theme	mass	506:509	arg1	 1					539:540	 1	539:540	 1	539:540	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	8	30	theme	cellulose	1111:1119	arg1	nanoparticles					1121:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	zein/carboxymethyl cellulose nanoparticles	1092:1133	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	0	31	theme	resveratrol	34:44	arg1	Co-encapsulation					0:15	Co-encapsulation	0:15	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.	0:143	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	3	32	with	nanoparticles	437:449	arg1	size					469:472	the smallest size	456:472	the smallest size (204.6 nm)	456:483	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	3	32	with	nanoparticles	437:449	arg1	nm					481:482	204.6 nm	475:482	204.6 nm	475:482	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	3	33	theme	zein	520:523	arg1	ratio					511:515	the mass ratio	502:515	the mass ratio of zein to CMC	502:530	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	3	33	theme	zein	520:523	arg1	 1					539:540	 1	539:540	 1	539:540	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	0	34	theme	cellulose	68:76	arg1	nanoparticles					78:90	zein/carboxymethyl cellulose nanoparticles	49:90	zein/carboxymethyl cellulose nanoparticles	49:90	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	4	35	theme	hydrophobic	564:574	arg1	interactions					576:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	8	36	theme	foods	1252:1256	arg1	development					1226:1236	the development	1222:1236	the development of functional foods, supplements, and pharmaceuticals	1222:1290	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	0	37	theme	zein/carboxymethyl	49:66	arg1	nanoparticles					78:90	zein/carboxymethyl cellulose nanoparticles	49:90	zein/carboxymethyl cellulose nanoparticles	49:90	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	4	38	theme	dominant	594:601	arg1	forces					611:616	dominant binding forces	594:616	dominant binding forces	594:616	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	8	39	theme	functional	1241:1250	arg1	foods					1252:1256	functional foods	1241:1256	functional foods	1241:1256	Our results indicate that zein/carboxymethyl cellulose nanoparticles can be used to co-deliver combinations of bioactive compounds, which may be useful for the development of functional foods, supplements, and pharmaceuticals.					
36278431	2	40	theme	zein/carboxymethyl	287:304	arg1	nanoparticles					326:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	zein/carboxymethyl cellulose composite nanoparticles	287:338	In this work, zein/carboxymethyl cellulose composite nanoparticles were successfully prepared using antisolvent precipitation methods.					
36278431	6	41	theme	nutraceuticals	828:841	arg1	Encapsulation					807:819	Encapsulation	807:819	Encapsulation of the nutraceuticals	807:841	Encapsulation of the nutraceuticals was shown to delay their release under simulated gastrointestinal conditions, which may be beneficial for some applications.					
36278431	1	42	theme	Oral	145:148	arg1	administration					150:163	Oral administration	145:163	Oral administration of combinations of specific nutrients and nutraceuticals	145:220	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36278431	4	43	theme	bonding	552:558	arg1	interactions					576:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	2	44	theme	precipitation	385:397	arg1	methods					399:405	antisolvent precipitation methods	373:405	antisolvent precipitation methods	373:405	In this work, zein/carboxymethyl cellulose composite nanoparticles were successfully prepared using antisolvent precipitation methods.					
36278431	7	45	theme	in	1006:1007	arg1	bioaccessibility					1015:1030	the in vitro bioaccessibility	1002:1030	the in vitro bioaccessibility of the quercetin and resveratrol	1002:1063	Moreover, encapsulation increased the in vitro bioaccessibility of the quercetin and resveratrol.					
36278431	3	46	theme	Zein/carboxymethyl	408:425	arg1	nanoparticles					437:449	Zein/carboxymethyl cellulose nanoparticles	408:449	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm)	408:483	Zein/carboxymethyl cellulose nanoparticles with the smallest size (204.6 nm) were formed when the mass ratio of zein to CMC was 2 : 1.					
36278431	4	47	theme	Hydrogen	543:550	arg1	interactions					576:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions	543:587	Hydrogen bonding and hydrophobic interactions were dominant binding forces to stabilize the composite nanoparticles.					
36278431	0	48	dep	Co-encapsulation	0:15	arg1	characterization					93:108	characterization	93:108	characterization	93:108	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	0	48	dep	Co-encapsulation	0:15	arg1	digestion					134:142	in vitro digestion	125:142	in vitro digestion	125:142	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	0	48	dep	Co-encapsulation	0:15	arg1	stability					111:119	stability	111:119	stability	111:119	Co-encapsulation of quercetin and resveratrol in zein/carboxymethyl cellulose nanoparticles: characterization, stability and in vitro digestion.					
36278431	1	49	theme	combinations	168:179	arg1	administration					150:163	Oral administration	145:163	Oral administration of combinations of specific nutrients and nutraceuticals	145:220	Oral administration of combinations of specific nutrients and nutraceuticals can provide synergistic health benefits to humans.					
36328284	7	0	theme	drinking	1228:1235	arg1	water					1237:1241	drinking water	1228:1241	drinking water (30 μg L-1)	1228:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	7	0	theme	drinking	1228:1235	arg1	L-1					1250:1252	30 μg L-1	1244:1252	30 μg L-1	1244:1252	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	7	1	from	10.98 mg L-1	1124:1135	arg1	wastewater					1108:1117	simulated wastewater	1098:1117	simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1098:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	5	2	theme	DFT	722:724	arg1	calculations					726:737	The DFT calculations	718:737	The DFT calculations	718:737	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	9	3	theme	high	1402:1405	arg1	performance					1407:1417	high performance	1402:1417	high performance	1402:1417	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	2	4	theme	efficient	376:384	arg1	adsorption					408:417	efficient and selective uranium adsorption	376:417	efficient and selective uranium adsorption	376:417	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	4	5	theme	only	662:665	arg1	4 h					667:669	only 4 h	662:669	only 4 h due to high nitrogen content of 6.57 mol kg-1	662:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	7	6	theme	simulated	1098:1106	arg1	wastewater					1108:1117	simulated wastewater	1098:1117	simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1098:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	9	7	theme	industrial	1497:1506	arg1	applications					1508:1519	practical industrial applications	1487:1519	practical industrial applications	1487:1519	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	0	8	theme	nuclear	122:128	arg1	waste					130:134	radioactive nuclear waste	110:134	radioactive nuclear waste	110:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	6	9	dep	times	1045:1049	arg1	that					1051:1054	that	1051:1054	that	1051:1054	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	9	10	contain	has	1463:1465	arg1	performance					1407:1417	high performance	1402:1417	high performance	1402:1417	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	9	10	contain	has	1463:1465	arg1	cost-effectiveness					1437:1454	cost-effectiveness	1437:1454	cost-effectiveness	1437:1454	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	9	10	contain	has	1463:1465	arg2	advantages					1473:1482	great advantages	1467:1482	great advantages	1467:1482	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	9	10	contain	has	1463:1465	arg1	practicality					1420:1431	practicality	1420:1431	practicality	1420:1431	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	6	11	theme	Adsorption	889:898	arg1	efficiency					900:909	Adsorption efficiency	889:909	Adsorption efficiency of U(VI) from simulated nuclear wastewater	889:952	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	3	12	theme	prepared	424:431	arg1	microspheres					442:453	The prepared chitosan microspheres	420:453	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength	420:520	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	0	13	theme	radioactive	110:120	arg1	waste					130:134	radioactive nuclear waste	110:134	radioactive nuclear waste	110:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	7	14	theme	μg	1142:1143	arg1	L-1					1145:1147	1 μg L-1	1140:1147	1 μg L-1	1140:1147	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	3	15	theme	environmental	553:565	arg1	benefits					567:574	cost-effectiveness and environmental benefits	530:574	cost-effectiveness and environmental benefits	530:574	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	7	16	theme	Agency	1202:1207	arg1	limits					1217:1222	the US Environmental Protection Agency uranium limits	1170:1222	the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1170:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	3	17	theme	cost-effectiveness	530:547	arg1	benefits					567:574	cost-effectiveness and environmental benefits	530:574	cost-effectiveness and environmental benefits	530:574	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	1	18	from	waste	181:185	arg1	extraction					145:154	Uranium extraction	137:154	Uranium extraction from radioactive nuclear waste	137:185	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	3	19	with	microspheres	442:453	arg1	strength					513:520	good mechanical strength	497:520	good mechanical strength	497:520	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	3	19	with	microspheres	442:453	arg1	size					468:471	uniform size	460:471	uniform size	460:471	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	3	19	with	microspheres	442:453	arg1	dispersion					482:491	uniform dispersion	474:491	uniform dispersion	474:491	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	3	20	theme	uniform	460:466	arg1	size					468:471	uniform size	460:471	uniform size	460:471	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	7	21	theme	uranium	1209:1215	arg1	limits					1217:1222	the US Environmental Protection Agency uranium limits	1170:1222	the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1170:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	7	22	theme	Protection	1191:1200	arg1	limits					1217:1222	the US Environmental Protection Agency uranium limits	1170:1222	the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1170:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	1	23	theme	sustainable	200:210	arg1	supply					219:224	sustainable energy supply	200:224	sustainable energy supply	200:224	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	7	24	theme	Environmental	1177:1189	arg1	limits					1217:1222	the US Environmental Protection Agency uranium limits	1170:1222	the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1170:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	1	25	theme	energy	212:217	arg1	supply					219:224	sustainable energy supply	200:224	sustainable energy supply	200:224	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	0	26	theme	Efficient	0:8	arg1	capture					24:30	Efficient and selective capture	0:30	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.	0:135	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	6	27	dep	U	914:914	arg1	VI					916:917	VI	916:917	VI	916:917	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	9	28	theme	0.4-PEI/ECH-CTS	1363:1377	arg1	microspheres					1379:1390	the 0.4-PEI/ECH-CTS microspheres	1359:1390	the 0.4-PEI/ECH-CTS microspheres	1359:1390	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	2	29	theme	uranium	400:406	arg1	adsorption					408:417	efficient and selective uranium adsorption	376:417	efficient and selective uranium adsorption	376:417	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	3	30	theme	mechanical	502:511	arg1	strength					513:520	good mechanical strength	497:520	good mechanical strength	497:520	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	4	31	theme	adsorption	618:627	arg1	capacity					629:636	the highest adsorption capacity	606:636	the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1	606:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	9	32	theme	great	1467:1471	arg1	advantages					1473:1482	great advantages	1467:1482	great advantages	1467:1482	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	3	33	theme	good	497:500	arg1	strength					513:520	good mechanical strength	497:520	good mechanical strength	497:520	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	0	34	theme	selective	14:22	arg1	capture					24:30	Efficient and selective capture	0:30	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.	0:135	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	4	35	theme	380.65 mg g-1	641:653	arg1	capacity					629:636	the highest adsorption capacity	606:636	the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1	606:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	5	36	theme	UO22+	786:790	arg1	UO22+					819:823	one UO22+	815:823	one UO22+ chelated with two -NH2 from two adsorption units, respectively	815:886	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	5	36	theme	UO22+	786:790	arg1	mode					778:781	the optimal coordination mode	753:781	the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS	753:810	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	6	37	theme	nuclear	935:941	arg1	wastewater					943:952	simulated nuclear wastewater	925:952	simulated nuclear wastewater	925:952	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	1	38	theme	ecological	230:239	arg1	security					241:248	ecological security	230:248	ecological security	230:248	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	0	39	theme	uranium	35:41	arg1	capture					24:30	Efficient and selective capture	0:30	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.	0:135	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	6	40	theme	simulated	925:933	arg1	wastewater					943:952	simulated nuclear wastewater	925:952	simulated nuclear wastewater	925:952	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	2	41	theme	polyethyleneimine-chitosan	261:286	arg1	n-PEI/ECH-CTS					311:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS	259:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5)	259:353	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	2	42	dep	n-PEI/ECH-CTS	311:323	arg1	0.5					350:352	0.5	350:352	0.5	350:352	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	6	43	from	wastewater	943:952	arg1	efficiency					900:909	Adsorption efficiency	889:909	Adsorption efficiency of U(VI) from simulated nuclear wastewater	889:952	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	5	44	theme	adsorption	857:866	arg1	units					868:872	two adsorption units	853:872	two adsorption units	853:872	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	5	45	theme	0.4-PEI/ECH-CTS	796:810	arg1	UO22+					819:823	one UO22+	815:823	one UO22+ chelated with two -NH2 from two adsorption units, respectively	815:886	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	5	45	theme	0.4-PEI/ECH-CTS	796:810	arg1	mode					778:781	the optimal coordination mode	753:781	the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS	753:810	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	8	46	theme	adsorption	1307:1316	arg1	efficiency					1318:1327	above 95% adsorption efficiency	1297:1327	above 95% adsorption efficiency	1297:1327	Besides, 0.4-PEI/ECH-CTS still maintains above 95% adsorption efficiency after seven cycles.					
36328284	0	47	theme	polyethyleneimine-modified	46:71	arg1	microspheres					92:103	polyethyleneimine-modified chitosan composite microspheres	46:103	polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste	46:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	7	48	dep	reduces	1087:1093	arg1	VI					1083:1084	VI	1083:1084	VI	1083:1084	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	8	49	dep	efficiency	1318:1327	arg1	%					1305:1305	%	1305:1305	%	1305:1305	Besides, 0.4-PEI/ECH-CTS still maintains above 95% adsorption efficiency after seven cycles.					
36328284	1	50	theme	Uranium	137:143	arg1	extraction					145:154	Uranium extraction	137:154	Uranium extraction from radioactive nuclear waste	137:185	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	3	51	theme	chitosan	433:440	arg1	microspheres					442:453	The prepared chitosan microspheres	420:453	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength	420:520	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	4	52	theme	highest	610:616	arg1	capacity					629:636	the highest adsorption capacity	606:636	the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1	606:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	5	53	theme	optimal	757:763	arg1	UO22+					819:823	one UO22+	815:823	one UO22+ chelated with two -NH2 from two adsorption units, respectively	815:886	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	5	53	theme	optimal	757:763	arg1	mode					778:781	the optimal coordination mode	753:781	the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS	753:810	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	4	54	theme	due	671:673	arg1	4 h					667:669	only 4 h	662:669	only 4 h due to high nitrogen content of 6.57 mol kg-1	662:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	9	55	theme	practical	1487:1495	arg1	applications					1508:1519	practical industrial applications	1487:1519	practical industrial applications	1487:1519	In short, the 0.4-PEI/ECH-CTS microspheres integrate high performance, practicality and cost-effectiveness, which has great advantages in practical industrial applications.					
36328284	1	56	theme	nuclear	173:179	arg1	waste					181:185	radioactive nuclear waste	161:185	radioactive nuclear waste	161:185	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	6	57	theme	Kd	980:981	arg1	up					992:993	up	992:993	up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions	992:1073	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	6	57	theme	Kd	980:981	arg1	value					983:987	the Kd value	976:987	the Kd value	976:987	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	5	58	theme	coordination	765:776	arg1	UO22+					819:823	one UO22+	815:823	one UO22+ chelated with two -NH2 from two adsorption units, respectively	815:886	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	5	58	theme	coordination	765:776	arg1	mode					778:781	the optimal coordination mode	753:781	the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS	753:810	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	0	59	from	waste	130:134	arg1	microspheres					92:103	polyethyleneimine-modified chitosan composite microspheres	46:103	polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste	46:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	8	60	dep	%	1305:1305	arg1	95					1303:1304	95	1303:1304	95	1303:1304	Besides, 0.4-PEI/ECH-CTS still maintains above 95% adsorption efficiency after seven cycles.					
36328284	4	61	theme	high	678:681	arg1	content					692:698	high nitrogen content	678:698	high nitrogen content of 6.57 mol kg-1	678:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	6	62	theme	U	914:914	arg1	efficiency					900:909	Adsorption efficiency	889:909	Adsorption efficiency of U(VI) from simulated nuclear wastewater	889:952	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	1	63	theme	radioactive	161:171	arg1	waste					181:185	radioactive nuclear waste	161:185	radioactive nuclear waste	161:185	Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security.					
36328284	6	64	theme	ions	1070:1073	arg1	times					1045:1049	1.7 × 104-6.1 × 104 times	1025:1049	1.7 × 104-6.1 × 104 times that of coexisting ions	1025:1073	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	0	65	theme	composite	82:90	arg1	microspheres					92:103	polyethyleneimine-modified chitosan composite microspheres	46:103	polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste	46:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	2	66	theme	microspheres	298:309	arg1	n-PEI/ECH-CTS					311:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS	259:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5)	259:353	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	4	67	theme	6.57 mol kg-1	703:715	arg1	content					692:698	high nitrogen content	678:698	high nitrogen content of 6.57 mol kg-1	678:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36328284	2	68	theme	selective	390:398	arg1	adsorption					408:417	efficient and selective uranium adsorption	376:417	efficient and selective uranium adsorption	376:417	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	3	69	theme	uniform	474:480	arg1	dispersion					482:491	uniform dispersion	474:491	uniform dispersion	474:491	The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits.					
36328284	6	70	theme	coexisting	1059:1068	arg1	ions					1070:1073	coexisting ions	1059:1073	coexisting ions	1059:1073	Adsorption efficiency of U(VI) from simulated nuclear wastewater achieves to 100%, and the Kd value is up to 1.1 × 104 mL g-1, which is 1.7 × 104-6.1 × 104 times that of coexisting ions.					
36328284	0	71	theme	chitosan	73:80	arg1	microspheres					92:103	polyethyleneimine-modified chitosan composite microspheres	46:103	polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste	46:134	Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste.					
36328284	5	72	from	units	868:872	arg1	-NH2					843:846	two -NH2	839:846	two -NH2	839:846	The DFT calculations confirms that the optimal coordination mode of UO22+ and 0.4-PEI/ECH-CTS is one UO22+ chelated with two -NH2 from two adsorption units, respectively.					
36328284	2	73	theme	composite	288:296	arg1	n-PEI/ECH-CTS					311:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS	259:323	a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5)	259:353	Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption.					
36328284	7	74	theme	US	1174:1175	arg1	limits					1217:1222	the US Environmental Protection Agency uranium limits	1170:1222	the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1)	1170:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	7	75	theme	μg	1247:1248	arg1	water					1237:1241	drinking water	1228:1241	drinking water (30 μg L-1)	1228:1253	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	7	75	theme	μg	1247:1248	arg1	L-1					1250:1252	30 μg L-1	1244:1252	30 μg L-1	1244:1252	The CU(VI) reduces in simulated wastewater from 10.98 mg L-1 to 1 μg L-1, which is well below the US Environmental Protection Agency uranium limits for drinking water (30 μg L-1).					
36328284	4	76	theme	nitrogen	683:690	arg1	content					692:698	high nitrogen content	678:698	high nitrogen content of 6.57 mol kg-1	678:715	The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g-1 within only 4 h due to high nitrogen content of 6.57 mol kg-1.					
36257365	0	0	theme	electron	89:96	arg1	transport					107:115	electron and hole transport	89:115	transport	107:115	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	4	1	theme	diffraction	532:542	arg1	spectra					544:550	The diffraction spectra	528:550	The diffraction spectra from chitosan for pH 9	528:573	The diffraction spectra from chitosan for pH 9 is 19.56°.					
36257365	4	1	theme	diffraction	532:542	arg1	19.56°					578:583	19.56°	578:583	19.56°	578:583	The diffraction spectra from chitosan for pH 9 is 19.56°.					
36257365	4	2	from	chitosan	557:564	arg1	spectra					544:550	The diffraction spectra	528:550	The diffraction spectra from chitosan for pH 9	528:573	The diffraction spectra from chitosan for pH 9 is 19.56°.					
36257365	4	2	from	chitosan	557:564	arg1	19.56°					578:583	19.56°	578:583	19.56°	578:583	The diffraction spectra from chitosan for pH 9 is 19.56°.					
36257365	6	3	theme	FTIR	848:851	arg1	spectra					853:859	the FTIR spectra	844:859	the FTIR spectra	844:859	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	7	4	theme	self-cleaning	1008:1020	arg1	performance					1022:1032	the best self-cleaning performance	999:1032	the best self-cleaning performance for dye stain which completely lost after being exposed for 15 h irradiation	999:1109	The pH 9 is the best self-cleaning performance for dye stain which completely lost after being exposed for 15 h irradiation.					
36257365	7	4	theme	self-cleaning	1008:1020	arg1	pH 9					991:994	The pH 9	987:994	The pH 9	987:994	The pH 9 is the best self-cleaning performance for dye stain which completely lost after being exposed for 15 h irradiation.					
36257365	8	5	theme	new	1256:1258	arg1	material					1274:1281	new self-cleaning material	1256:1281	new self-cleaning material in future	1256:1291	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	0	6	theme	hole	102:105	arg1	transport					107:115	electron and hole transport	89:115	transport	107:115	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	2	7	with	15 h	351:354	arg1	dye					361:363	dye	361:363	dye	361:363	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	2	8	theme	self-cleaning	257:269	arg1	test					271:274	The self-cleaning test	253:274	The self-cleaning test	253:274	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	3	9	dep	Infra-Red	481:489	arg1	FTIR					492:495	FTIR	492:495	FTIR	492:495	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	5	10	theme	wavenumber	677:686	arg1	3495 cm-1					688:696	the wavenumber 3495 cm-1	673:696	the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan	673:749	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
36257365	5	11	theme	wavenumbers	612:622	arg1	621 cm-1					634:641	the wavenumbers 422 cm-1- 621 cm-1	608:641	the wavenumbers 422 cm-1- 621 cm-1	608:641	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
36257365	6	12	theme	vibration	919:927	arg1	modes					929:933	two optical photon vibration modes	900:933	two optical photon vibration modes (∆ (LO-TO))	900:945	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	1	13	theme	ZnO/chitosan	118:129	arg1	fabric					143:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	13	theme	ZnO/chitosan	118:129	arg1	self-cleaning					172:184	a self-cleaning	170:184	a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9	170:250	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	3	14	theme	X-Ray	438:442	arg1	XRD					457:459	XRD	457:459	XRD	457:459	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	3	14	theme	X-Ray	438:442	arg1	Diffraction					444:454	X-Ray Diffraction	438:454	X-Ray Diffraction (XRD)	438:460	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	8	15	theme	high	1237:1240	arg1	potential					1242:1250	high potential	1237:1250	high potential for new self-cleaning material in future	1237:1291	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	3	16	theme	ZnO/chitosan	389:400	arg1	composites					402:411	ZnO/chitosan composites	389:411	ZnO/chitosan composites	389:411	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	7	17	theme	15 h	1094:1097	arg1	irradiation					1099:1109	15 h irradiation	1094:1109	15 h irradiation	1094:1109	The pH 9 is the best self-cleaning performance for dye stain which completely lost after being exposed for 15 h irradiation.					
36257365	8	18	theme	best	1135:1138	arg1	self-cleaning					1140:1152	the best self-cleaning	1131:1152	the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO))	1131:1225	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	8	19	from	material	1274:1281	arg1	future					1286:1291	future	1286:1291	future	1286:1291	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	0	20	theme	High	0:3	arg1	efficiency					5:14	High efficiency	0:14	High efficiency self-cleaning of	0:31	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	6	21	theme	photon	912:917	arg1	modes					929:933	two optical photon vibration modes	900:933	two optical photon vibration modes (∆ (LO-TO))	900:945	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	5	22	theme	vibration	590:598	arg1	bond					600:603	The vibration bond	586:603	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1	586:641	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
36257365	3	23	dep	Fourier	463:469	arg1	Transform					471:479	Transform	471:479	Transform Infra-Red (FTIR)	471:496	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	8	24	theme	due	1154:1156	arg1	self-cleaning					1140:1152	the best self-cleaning	1131:1152	the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO))	1131:1225	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	6	25	theme	optical	904:910	arg1	modes					929:933	two optical photon vibration modes	900:933	two optical photon vibration modes (∆ (LO-TO))	900:945	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	5	26	theme	ZnO	657:659	arg1	bond					661:664	ZnO bond	657:664	ZnO bond	657:664	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
36257365	6	27	theme	Optical	752:758	arg1	properties					760:769	Optical properties	752:769	Optical properties	752:769	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	8	28	theme	self-cleaning	1260:1272	arg1	material					1274:1281	new self-cleaning material	1256:1281	new self-cleaning material in future	1256:1291	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	2	29	theme	clothing	373:380	arg1	stain					382:386	the clothing stain	369:386	the clothing stain	369:386	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	0	30	theme	self-cleaning	16:28	arg1	efficiency					5:14	High efficiency	0:14	High efficiency self-cleaning of	0:31	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	3	31	theme	UV-Visible	503:512	arg1	spectroscopy					514:525	UV-Visible spectroscopy	503:525	UV-Visible spectroscopy	503:525	ZnO/chitosan composites were characterized using X-Ray Diffraction (XRD), Fourier Transform Infra-Red (FTIR), and UV-Visible spectroscopy.					
36257365	1	32	theme	sol-gel	209:215	arg1	method					217:222	sol-gel method	209:222	sol-gel method for various pH	209:237	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	6	33	theme	KK	810:811	arg1	relation					814:821	the Kamers Kronig (KK) relation	791:821	the Kamers Kronig (KK) relation which was applied to the FTIR spectra	791:859	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	8	34	theme	crystallite	1174:1184	arg1	size					1186:1189	the smallest crystallite size	1161:1189	the smallest crystallite size and highest bandgap and (∆ (LO-TO))	1161:1225	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	0	35	theme	additional	57:66	arg1	chitosan					68:75	additional chitosan	57:75	additional chitosan for helping electron and hole transport	57:115	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	6	36	theme	highest	875:881	arg1	distance					883:890	the highest distance	871:890	the highest distance between two optical photon vibration modes (∆ (LO-TO))	871:945	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	6	36	theme	highest	875:881	arg1	199 cm-1					950:957	199 cm-1	950:957	199 cm-1 was obtained when the pH 9	950:984	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	5	37	theme	422 cm-1-	624:632	arg1	621 cm-1					634:641	the wavenumbers 422 cm-1- 621 cm-1	608:641	the wavenumbers 422 cm-1- 621 cm-1	608:641	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
36257365	2	38	theme	cloth	311:315	arg1	samples					317:323	the cloth samples	307:323	the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain	307:386	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	6	39	theme	Kronig	802:807	arg1	relation					814:821	the Kamers Kronig (KK) relation	791:821	the Kamers Kronig (KK) relation which was applied to the FTIR spectra	791:859	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	1	40	dep	self-cleaning	172:184	arg1	7					243:243	7	243:243	7	243:243	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	40	dep	self-cleaning	172:184	arg1	9					250:250	9	250:250	9	250:250	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	40	dep	self-cleaning	172:184	arg1	5					240:240	5	240:240	5	240:240	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	41	theme	coated	131:136	arg1	fabric					143:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	41	theme	coated	131:136	arg1	self-cleaning					172:184	a self-cleaning	170:184	a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9	170:250	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	6	42	theme	Kamers	795:800	arg1	relation					814:821	the Kamers Kronig (KK) relation	791:821	the Kamers Kronig (KK) relation which was applied to the FTIR spectra	791:859	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	1	43	theme	wool	138:141	arg1	fabric					143:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric	118:148	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	43	theme	wool	138:141	arg1	self-cleaning					172:184	a self-cleaning	170:184	a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9	170:250	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	1	44	theme	various	228:234	arg1	pH					236:237	various pH	228:237	various pH	228:237	ZnO/chitosan coated wool fabric has been applied as a self-cleaning which obtained through sol-gel method for various pH: 5, 7, and 9.					
36257365	8	45	dep	bandgap	1203:1209	arg1	∆					1216:1216	∆	1216:1216	∆ (LO-TO)	1216:1224	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	8	45	dep	bandgap	1203:1209	arg1	highest					1195:1201	highest	1195:1201	highest	1195:1201	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	8	45	dep	bandgap	1203:1209	arg1	LO-TO					1219:1223	LO-TO	1219:1223	LO-TO	1219:1223	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	8	46	theme	bandgap	1203:1209	arg1	size					1186:1189	the smallest crystallite size	1161:1189	the smallest crystallite size and highest bandgap and (∆ (LO-TO))	1161:1225	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	8	47	theme	smallest	1165:1172	arg1	size					1186:1189	the smallest crystallite size	1161:1189	the smallest crystallite size and highest bandgap and (∆ (LO-TO))	1161:1225	Samples pH 9 shows the best self-cleaning due to the smallest crystallite size and highest bandgap and (∆ (LO-TO)) indicated high potential for new self-cleaning material in future.					
36257365	7	48	theme	dye	1038:1040	arg1	stain					1042:1046	dye stain	1038:1046	dye stain which completely lost after being exposed for 15 h irradiation	1038:1109	The pH 9 is the best self-cleaning performance for dye stain which completely lost after being exposed for 15 h irradiation.					
36257365	6	49	dep	modes	929:933	arg1	LO-TO					939:943	LO-TO	939:943	LO-TO	939:943	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	6	49	dep	modes	929:933	arg1	∆					936:936	∆	936:936	∆ (LO-TO)	936:944	Optical properties were analysed using the Kamers Kronig (KK) relation which was applied to the FTIR spectra and shows the highest distance between two optical photon vibration modes (∆ (LO-TO)) is 199 cm-1 was obtained when the pH 9.					
36257365	2	50	dep	15 h	351:354	arg1	up					345:346	up	345:346	up	345:346	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	0	51	with	ZnO	48:50	arg1	chitosan					68:75	additional chitosan	57:75	additional chitosan for helping electron and hole transport	57:115	High efficiency self-cleaning of nanocomposites ZnO with additional chitosan for helping electron and hole transport.					
36257365	2	52	theme	UVA-UVB	331:337	arg1	lamps					339:343	UVA-UVB lamps	331:343	UVA-UVB lamps up to 15 h with dye for the clothing stain	331:386	The self-cleaning test was carried out by irradiating the cloth samples using UVA-UVB lamps up to 15 h with dye for the clothing stain.					
36257365	5	53	from	621 cm-1	634:641	arg1	bond					600:603	The vibration bond	586:603	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1	586:641	The vibration bond at the wavenumbers 422 cm-1- 621 cm-1 identified as ZnO bond and at the wavenumber 3495 cm-1 identified for stretching -OH and -NH2 from chitosan.					
37390694	10	0	theme	promising	1436:1444	arg1	strategy					1446:1453	a promising strategy	1434:1453	a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components	1434:1610	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	11	1	theme	sustainable	1763:1773	arg1	agriculture					1775:1785	sustainable agriculture	1763:1785	sustainable agriculture	1763:1785	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	7	2	from	decline	1141:1147	arg1	crystallinity					1156:1168	the crystallinity	1152:1168	the crystallinity of roots cellulose	1152:1187	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	3	3	theme	alleviation	508:518	arg1	mechanisms					483:492	the mechanisms	479:492	the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis	479:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	4	4	theme	plant	668:672	arg1	biomass					674:680	plant biomass	668:680	plant biomass	668:680	The results showed that salt stress hindered plant biomass and root growth in cotton.					
37390694	1	5	theme	major	144:148	arg1	stresses					158:165	the major abiotic stresses	140:165	the major abiotic stresses that impair agricultural production	140:201	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	1	6	theme	stresses	158:165	arg1	stresses					158:165	the major abiotic stresses	140:165	the major abiotic stresses that impair agricultural production	140:201	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	1	6	theme	stresses	158:165	arg1	one					133:135	one	133:135	one	133:135	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	8	7	theme	pectin	1267:1272	arg1	contents					1220:1227	the contents	1216:1227	the contents of chelated pectin and alkali-soluble pectin	1216:1272	Boron supply also reduced the contents of chelated pectin and alkali-soluble pectin.					
37390694	3	8	theme	salt	523:526	arg1	stress					528:533	salt stress	523:533	salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis	523:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	3	9	theme	substances	555:564	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	9	10	theme	cellulose	1385:1393	arg1	accumulation					1395:1406	cellulose accumulation	1385:1406	cellulose accumulation	1385:1406	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	8	11	theme	Boron	1190:1194	arg1	supply					1196:1201	Boron supply	1190:1201	Boron supply	1190:1201	Boron supply also reduced the contents of chelated pectin and alkali-soluble pectin.					
37390694	10	12	theme	plant	1518:1522	arg1	growth					1524:1529	plant growth	1518:1529	plant growth	1518:1529	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	11	13	theme	stress	1711:1716	arg1	effects					1695:1701	the effects	1691:1701	the effects of salt stress on plants	1691:1726	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	3	14	theme	structure	577:585	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	10	15	theme	cell	1591:1594	arg1	components					1601:1610	root cell wall components	1586:1610	root cell wall components	1586:1610	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	3	16	theme	cell	567:570	arg1	structure					577:585	cell wall structure	567:585	cell wall structure	567:585	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	6	17	theme	soluble	946:952	arg1	protein					954:960	soluble protein	946:960	soluble protein	946:960	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	0	18	theme	cell	65:68	arg1	structure					75:83	cell wall structure	65:83	cell wall structure	65:83	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	6	19	theme	proline	937:943	arg1	accumulation					921:932	the accumulation	917:932	the accumulation of proline, soluble protein, and soluble sugar	917:979	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	8	20	theme	pectin	1241:1246	arg1	contents					1220:1227	the contents	1216:1227	the contents of chelated pectin and alkali-soluble pectin	1216:1272	Boron supply also reduced the contents of chelated pectin and alkali-soluble pectin.					
37390694	3	21	from	alleviation	508:518	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	8	22	theme	alkali-soluble	1252:1265	arg1	pectin					1267:1272	alkali-soluble pectin	1252:1272	alkali-soluble pectin	1252:1272	Boron supply also reduced the contents of chelated pectin and alkali-soluble pectin.					
37390694	7	23	theme	X-ray	1093:1097	arg1	diffraction					1099:1109	X-ray diffraction	1093:1109	X-ray diffraction (XRD) analysis	1093:1124	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	7	23	theme	X-ray	1093:1097	arg1	XRD					1112:1114	XRD	1112:1114	XRD	1112:1114	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	2	24	theme	wall	391:394	arg1	modification					396:407	cell wall modification	386:407	cell wall modification	386:407	However, the regulatory mechanism of how B improves salt resistance via cell wall modification remains unknown.					
37390694	2	25	theme	regulatory	327:336	arg1	mechanism					338:346	the regulatory mechanism	323:346	the regulatory mechanism of how B improves salt resistance via cell wall modification	323:407	However, the regulatory mechanism of how B improves salt resistance via cell wall modification remains unknown.					
37390694	2	26	theme	salt	366:369	arg1	resistance					371:380	salt resistance	366:380	salt resistance	366:380	However, the regulatory mechanism of how B improves salt resistance via cell wall modification remains unknown.					
37390694	5	27	theme	cell	768:771	arg1	wall					773:776	the root cell wall	759:776	the root cell wall	759:776	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	1	28	theme	cell	247:250	arg1	composition					252:262	plant cell composition	241:262	plant cell composition	241:262	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	3	29	theme	ion	606:608	arg1	homeostasis					610:620	ion homeostasis	606:620	ion homeostasis	606:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	9	30	theme	exogenous	1353:1361	arg1	B					1363:1363	exogenous B	1353:1363	exogenous B	1353:1363	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	0	31	theme	salt	28:31	arg1	stress					33:38	salt stress	28:38	salt stress in cotton	28:48	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	6	32	theme	soluble	967:973	arg1	sugar					975:979	soluble sugar	967:979	soluble sugar	967:979	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	3	33	theme	components	591:600	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	9	34	theme	Fourier-transform	1275:1291	arg1	FTIR					1316:1319	FTIR	1316:1319	FTIR	1316:1319	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	9	34	theme	Fourier-transform	1275:1291	arg1	spectroscopy					1302:1313	Fourier-transform infrared spectroscopy	1275:1313	Fourier-transform infrared spectroscopy (FTIR) analysis	1275:1329	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	7	35	theme	cellulose	1179:1187	arg1	crystallinity					1156:1168	the crystallinity	1152:1168	the crystallinity of roots cellulose	1152:1187	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	11	36	theme	invaluable	1636:1645	arg1	insights					1647:1654	invaluable insights	1636:1654	invaluable insights	1636:1654	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	6	37	from	content	1043:1049	arg1	roots					1073:1077	the roots	1069:1077	the roots	1069:1077	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	9	38	theme	spectroscopy	1302:1313	arg1	analysis					1322:1329	Fourier-transform infrared spectroscopy (FTIR) analysis	1275:1329	Fourier-transform infrared spectroscopy (FTIR) analysis	1275:1329	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	11	39	contain	have	1741:1744	arg1	insights					1647:1654	invaluable insights	1636:1654	invaluable insights	1636:1654	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	11	39	contain	have	1741:1744	arg2	implications					1746:1757	implications	1746:1757	implications for sustainable agriculture	1746:1785	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	5	40	theme	Electron	807:814	arg1	TEM					828:830	TEM	828:830	TEM	828:830	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	5	40	theme	Electron	807:814	arg1	Microscope					816:825	Transmission Electron Microscope	794:825	Transmission Electron Microscope (TEM) analysis	794:840	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	6	41	theme	B	859:859	arg1	presence					847:854	The presence	843:854	The presence of B	843:859	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	6	42	theme	Cl-	1020:1022	arg1	content					1001:1007	the content	997:1007	the content of Na+ and Cl-	997:1022	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	6	43	theme	Na+	1012:1014	arg1	content					1001:1007	the content	997:1007	the content of Na+ and Cl-	997:1022	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	3	44	theme	B-mediated	497:506	arg1	alleviation					508:518	B-mediated alleviation	497:518	B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis	497:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	10	45	theme	adverse	1474:1480	arg1	impact					1482:1487	the adverse impact	1470:1487	the adverse impact of salt stress	1470:1502	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	5	46	theme	Microscope	816:825	arg1	analysis					833:840	Transmission Electron Microscope (TEM) analysis	794:840	Transmission Electron Microscope (TEM) analysis	794:840	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	5	47	theme	Transmission	794:805	arg1	TEM					828:830	TEM	828:830	TEM	828:830	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	5	47	theme	Transmission	794:805	arg1	Microscope					816:825	Transmission Electron Microscope	794:825	Transmission Electron Microscope (TEM) analysis	794:840	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	11	48	from	effects	1695:1701	arg1	plants					1721:1726	plants	1721:1726	plants	1721:1726	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	5	49	theme	salt	719:722	arg1	stress					724:729	salt stress	719:729	salt stress	719:729	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	3	50	theme	stress	528:533	arg1	alleviation					508:518	B-mediated alleviation	497:518	B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis	497:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	1	51	theme	abiotic	150:156	arg1	stresses					158:165	the major abiotic stresses	140:165	the major abiotic stresses that impair agricultural production	140:201	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	6	52	theme	Ca2+	1061:1064	arg1	content					1043:1049	the content	1039:1049	the content of K+ and Ca2+ in the roots	1039:1077	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	10	53	theme	stress	1497:1502	arg1	impact					1482:1487	the adverse impact	1470:1487	the adverse impact of salt stress	1470:1502	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	11	54	theme	salt	1706:1709	arg1	stress					1711:1716	salt stress	1706:1716	salt stress	1706:1716	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	5	55	theme	wall	773:776	arg1	morphology					745:754	the morphology	741:754	the morphology of the root cell wall	741:776	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	6	56	theme	K+	1054:1055	arg1	content					1043:1049	the content	1039:1049	the content of K+ and Ca2+ in the roots	1039:1077	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	3	57	theme	osmotic	547:553	arg1	substances					555:564	osmotic substances	547:564	osmotic substances	547:564	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	1	58	theme	agricultural	179:190	arg1	production					192:201	agricultural production	179:201	agricultural production	179:201	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	6	59	theme	adverse	890:896	arg1	effects					898:904	these adverse effects	884:904	these adverse effects	884:904	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	3	60	theme	wall	572:575	arg1	structure					577:585	cell wall structure	567:585	cell wall structure	567:585	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	1	61	theme	Salt	107:110	arg1	stress					112:117	Salt stress	107:117	Salt stress	107:117	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	3	62	from	stress	528:533	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	6	63	theme	protein	954:960	arg1	accumulation					921:932	the accumulation	917:932	the accumulation of proline, soluble protein, and soluble sugar	917:979	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	10	64	theme	salt	1492:1495	arg1	stress					1497:1502	salt stress	1492:1502	salt stress	1492:1502	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	0	65	theme	wall	70:73	arg1	structure					75:83	cell wall structure	65:83	cell wall structure	65:83	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	4	66	theme	salt	647:650	arg1	stress					652:657	salt stress	647:657	salt stress	647:657	The results showed that salt stress hindered plant biomass and root growth in cotton.					
37390694	7	67	theme	diffraction	1099:1109	arg1	analysis					1117:1124	X-ray diffraction (XRD) analysis	1093:1124	X-ray diffraction (XRD) analysis	1093:1124	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	1	68	theme	salt	301:304	arg1	stress					306:311	salt stress	301:311	salt stress	301:311	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	8	69	theme	chelated	1232:1239	arg1	pectin					1241:1246	chelated pectin	1232:1246	chelated pectin	1232:1246	Boron supply also reduced the contents of chelated pectin and alkali-soluble pectin.					
37390694	3	70	theme	present	430:436	arg1	study					438:442	The present study	426:442	The present study	426:442	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	0	71	theme	homeostasis	93:103	arg1	"					104:104	ion homeostasis"	89:104	ion homeostasis"	89:104	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	11	72	theme	B	1673:1673	arg1	role					1665:1668	the role	1661:1668	the role of B in ameliorating the effects of salt stress on plants	1661:1726	This study may provide invaluable insights into the role of B in ameliorating the effects of salt stress on plants, which could have implications for sustainable agriculture.					
37390694	0	73	from	stress	33:38	arg1	cotton					43:48	cotton	43:48	cotton	43:48	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	10	74	theme	ionic	1557:1561	arg1	stresses					1563:1570	osmotic and ionic stresses	1545:1570	osmotic and ionic stresses	1545:1570	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	0	75	theme	Exogenous	1:9	arg1	boron					11:15	"Exogenous boron	0:15	"Exogenous boron	0:15	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	2	76	theme	cell	386:389	arg1	modification					396:407	cell wall modification	386:407	cell wall modification	386:407	However, the regulatory mechanism of how B improves salt resistance via cell wall modification remains unknown.					
37390694	4	77	theme	root	686:689	arg1	growth					691:696	root growth	686:696	root growth	686:696	The results showed that salt stress hindered plant biomass and root growth in cotton.					
37390694	3	78	from	terms	538:542	arg1	alleviation					508:518	B-mediated alleviation	497:518	B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis	497:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	10	79	theme	osmotic	1545:1551	arg1	stresses					1563:1570	osmotic and ionic stresses	1545:1570	osmotic and ionic stresses	1545:1570	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	5	80	theme	root	763:766	arg1	wall					773:776	the root cell wall	759:776	the root cell wall	759:776	Moreover, salt stress disrupted the morphology of the root cell wall as evidenced by Transmission Electron Microscope (TEM) analysis.					
37390694	1	81	theme	plant	241:245	arg1	composition					252:262	plant cell composition	241:262	plant cell composition	241:262	Salt stress is considered one of the major abiotic stresses that impair agricultural production, while boron (B) is indispensable for plant cell composition and has also been found to alleviate salt stress.					
37390694	10	82	theme	root	1586:1589	arg1	components					1601:1610	root cell wall components	1586:1610	root cell wall components	1586:1610	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
37390694	6	83	theme	sugar	975:979	arg1	accumulation					921:932	the accumulation	917:932	the accumulation of proline, soluble protein, and soluble sugar	917:979	The presence of B effectively alleviated these adverse effects, promoting the accumulation of proline, soluble protein, and soluble sugar, while reducing the content of Na+ and Cl- and augmenting the content of K+ and Ca2+ in the roots.					
37390694	0	84	theme	ion	89:91	arg1	"					104:104	ion homeostasis"	89:104	ion homeostasis"	89:104	"Exogenous boron alleviates salt stress in cotton by maintaining cell wall structure and ion homeostasis".					
37390694	7	85	theme	roots	1173:1177	arg1	cellulose					1179:1187	roots cellulose	1173:1187	roots cellulose	1173:1187	Furthermore, X-ray diffraction (XRD) analysis demonstrated a decline in the crystallinity of roots cellulose.					
37390694	9	86	theme	infrared	1293:1300	arg1	FTIR					1316:1319	FTIR	1316:1319	FTIR	1316:1319	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	9	86	theme	infrared	1293:1300	arg1	spectroscopy					1302:1313	Fourier-transform infrared spectroscopy	1275:1313	Fourier-transform infrared spectroscopy (FTIR) analysis	1275:1329	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	9	87	from	decline	1374:1380	arg1	accumulation					1395:1406	cellulose accumulation	1385:1406	cellulose accumulation	1385:1406	Fourier-transform infrared spectroscopy (FTIR) analysis further affirmed that exogenous B led to a decline in cellulose accumulation.					
37390694	3	88	theme	homeostasis	610:620	arg1	terms					538:542	terms	538:542	terms of osmotic substances, cell wall structure and components and ion homeostasis	538:620	The present study primarily focused on investigating the mechanisms of B-mediated alleviation of salt stress in terms of osmotic substances, cell wall structure and components and ion homeostasis.					
37390694	10	89	theme	wall	1596:1599	arg1	components					1601:1610	root cell wall components	1586:1610	root cell wall components	1586:1610	In conclusion, B offered a promising strategy for mitigating the adverse impact of salt stress and enhancing plant growth by countering osmotic and ionic stresses and modifying root cell wall components.					
36362135	1	0	theme	rice	116:119	arg1	composition					74:84	composition	74:84	composition	74:84	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	0	theme	rice	116:119	arg1	properties					102:111	nutritional properties	90:111	nutritional properties	90:111	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	0	theme	rice	116:119	arg1	product					129:135	the product	125:135	the product of the expression of genes in the developing seed	125:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	5	1	theme	seed	620:623	arg1	development					625:635	seed development	620:635	seed development in both wild and domesticated rice	620:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	9	2	theme	transcripts	1332:1342	arg1	number					1316:1321	A substantial number	1302:1321	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins	1302:1442	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	6	3	theme	protein	857:863	arg1	synthesis					865:873	protein synthesis	857:873	protein synthesis	857:873	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	2	4	from	rice	305:308	arg1	stages					262:267	different stages	252:267	different stages of seed development in domesticated rice	252:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	10	5	theme	metabolic	1537:1545	arg1	processes					1547:1555	metabolic processes	1537:1555	metabolic processes associated with seed development	1537:1588	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	6	6	theme	nucleic	765:771	arg1	processing					778:787	nucleic acid processing	765:787	nucleic acid processing	765:787	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	2	7	theme	gene	233:236	arg1	expression					238:247	gene expression	233:247	gene expression	233:247	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	2	8	theme	seed	272:275	arg1	development					277:287	seed development	272:287	seed development in domesticated rice	272:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	10	9	theme	expression	1482:1491	arg1	patterns					1465:1472	The patterns	1461:1472	The patterns of gene expression revealed in this study	1461:1514	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	7	10	theme	early	1050:1054	arg1	stage					1056:1060	the early stage	1046:1060	the early stage (5 days post anthesis (DPA))	1046:1089	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	9	11	theme	domestication	1366:1378	arg1	genes					1380:1384	domestication genes	1366:1384	domestication genes	1366:1384	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	4	12	theme	primary	393:399	arg1	pool					406:409	the primary gene pool	389:409	the primary gene pool of rice	389:417	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	1	13	from	seed	182:185	arg1	product					129:135	the product	125:135	the product of the expression of genes in the developing seed	125:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	13	from	seed	182:185	arg1	properties					102:111	nutritional properties	90:111	nutritional properties	90:111	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	13	from	seed	182:185	arg1	composition					74:84	composition	74:84	composition	74:84	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	10	14	theme	gene	1477:1480	arg1	expression					1482:1491	gene expression	1477:1491	gene expression revealed in this study	1477:1514	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	7	15	theme	sucrose	984:990	arg1	metabolism					992:1001	starch and sucrose metabolism	973:1001	metabolism	992:1001	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	5	16	from	genome	526:531	arg1	profiling					485:493	Transcriptome profiling	471:493	Transcriptome profiling of all coding sequences in the genome	471:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	4	17	theme	wild	374:377	arg1	taxa					379:382	wild taxa	374:382	wild taxa	374:382	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	7	18	theme	storage	1013:1019	arg1	proteins					1021:1028	seed storage proteins	1008:1028	seed storage proteins	1008:1028	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	10	19	theme	nutritional	1655:1665	arg1	value					1667:1671	nutritional value	1655:1671	nutritional value	1655:1671	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	7	20	theme	starch	973:978	arg1	metabolism					992:1001	starch and sucrose metabolism	973:1001	metabolism	992:1001	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	9	21	theme	sucrose	1398:1404	arg1	metabolism					1406:1415	starch and sucrose metabolism	1387:1415	starch and sucrose metabolism	1387:1415	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	7	22	from	development	1146:1156	arg1	rice					1188:1191	both wild and domesticated rice	1161:1191	both wild and domesticated rice	1161:1191	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	8	23	theme	hull	1222:1225	arg1	gene					1240:1243	black hull colour (Bh4) gene	1216:1243	black hull colour (Bh4) gene	1216:1243	However, in contrast, black hull colour (Bh4) gene was significantly expressed throughout seed development.					
36362135	1	24	from	expression	144:153	arg1	seed					182:185	the developing seed	167:185	the developing seed	167:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	0	25	theme	Rice	64:67	arg1	Seed					34:37	the Developing Seed	19:37	the Developing Seed of Wild and Domesticated Rice	19:67	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	9	26	theme	storage	1427:1433	arg1	proteins					1435:1442	seed storage proteins	1422:1442	seed storage proteins	1422:1442	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	2	27	from	development	277:287	arg1	rice					305:308	domesticated rice	292:308	domesticated rice	292:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	4	28	theme	rufipogon	449:457	arg1	taxa					464:467	rufipogon type taxa	449:467	rufipogon type taxa	449:467	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	7	29	theme	expression	924:933	arg1	level					910:914	The level	906:914	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins	906:1028	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	7	29	theme	expression	924:933	arg1	highest					1035:1041	highest	1035:1041	highest	1035:1041	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	4	30	theme	rice	414:417	arg1	pool					406:409	the primary gene pool	389:409	the primary gene pool of rice	389:417	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	5	31	theme	sequences	509:517	arg1	profiling					485:493	Transcriptome profiling	471:493	Transcriptome profiling of all coding sequences in the genome	471:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	0	32	theme	Domesticated	51:62	arg1	Rice					64:67	Wild and Domesticated Rice	42:67	Wild and Domesticated Rice	42:67	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	6	33	attach	linked	847:852	arg2	number					831:836	the highest number	819:836	the highest number of being linked to protein synthesis and starch/sucrose metabolism	819:903	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	6	33	attach	linked	847:852	arg1	synthesis					865:873	protein synthesis	857:873	protein synthesis	857:873	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	6	33	attach	linked	847:852	arg1	metabolism					894:903	starch/sucrose metabolism	879:903	starch/sucrose metabolism	879:903	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	0	34	theme	Gene	0:3	arg1	Expression					5:14	Gene Expression	0:14	Gene Expression in the Developing Seed of Wild and Domesticated Rice.	0:68	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	8	35	theme	seed	1284:1287	arg1	development					1289:1299	seed development	1284:1299	seed development	1284:1299	However, in contrast, black hull colour (Bh4) gene was significantly expressed throughout seed development.					
36362135	1	36	theme	nutritional	90:100	arg1	product					129:135	the product	125:135	the product of the expression of genes in the developing seed	125:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	36	theme	nutritional	90:100	arg1	properties					102:111	nutritional properties	90:111	nutritional properties	90:111	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	36	theme	nutritional	90:100	arg1	composition					74:84	composition	74:84	composition	74:84	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	10	37	theme	seed	1573:1576	arg1	development					1578:1588	seed development	1573:1588	seed development	1573:1588	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	0	38	theme	Developing	23:32	arg1	Seed					34:37	the Developing Seed	19:37	the Developing Seed of Wild and Domesticated Rice	19:67	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	2	39	theme	domesticated	292:303	arg1	rice					305:308	domesticated rice	292:308	domesticated rice	292:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	10	40	theme	grain	1637:1641	arg1	quality					1643:1649	rice grain quality	1632:1649	rice grain quality	1632:1649	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	10	41	theme	rice	1632:1635	arg1	quality					1643:1649	rice grain quality	1632:1649	rice grain quality	1632:1649	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	5	42	from	development	625:635	arg1	wild					645:648	wild	645:648	wild	645:648	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	42	from	development	625:635	arg1	rice					667:670	domesticated rice	654:670	domesticated rice	654:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	43	theme	different	600:608	arg1	stages					610:615	different stages	600:615	different stages of seed development in both wild and domesticated rice	600:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	44	from	rice	667:670	arg1	stages					610:615	different stages	600:615	different stages of seed development in both wild and domesticated rice	600:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	6	45	theme	starch/sucrose	879:892	arg1	metabolism					894:903	starch/sucrose metabolism	879:903	starch/sucrose metabolism	879:903	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	1	46	theme	developing	171:180	arg1	seed					182:185	the developing seed	167:185	the developing seed	167:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	2	47	theme	different	252:260	arg1	stages					262:267	different stages	252:267	different stages of seed development in domesticated rice	252:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	9	48	theme	novel	1326:1330	arg1	38					1345:1346	38	1345:1346	38	1345:1346	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	9	48	theme	novel	1326:1330	arg1	transcripts					1332:1342	novel transcripts	1326:1342	novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins	1326:1442	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	6	49	theme	acid	773:776	arg1	processing					778:787	nucleic acid processing	765:787	nucleic acid processing	765:787	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	2	50	theme	expression	238:247	arg1	level					224:228	the level	220:228	the level of gene expression	220:247	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	1	51	theme	expression	144:153	arg1	product					129:135	the product	125:135	the product of the expression of genes in the developing seed	125:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	51	theme	expression	144:153	arg1	properties					102:111	nutritional properties	90:111	nutritional properties	90:111	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	1	51	theme	expression	144:153	arg1	composition					74:84	composition	74:84	composition	74:84	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	10	52	from	differences	1617:1627	arg1	quality					1643:1649	rice grain quality	1632:1649	rice grain quality	1632:1649	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	10	52	from	differences	1617:1627	arg1	value					1667:1671	nutritional value	1655:1671	nutritional value	1655:1671	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	2	53	dep	investigate	208:218	arg1	Oryza					311:315	Oryza	311:315	Oryza	311:315	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	2	54	theme	development	277:287	arg1	stages					262:267	different stages	252:267	different stages of seed development in domesticated rice	252:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	1	55	theme	genes	158:162	arg1	expression					144:153	the expression	140:153	the expression of genes in the developing seed	140:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	0	56	from	Expression	5:14	arg1	Seed					34:37	the Developing Seed	19:37	the Developing Seed of Wild and Domesticated Rice	19:67	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	6	57	theme	transcriptional	737:751	arg1	regulation					753:762	transcriptional regulation	737:762	transcriptional regulation	737:762	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	4	58	theme	gene	401:404	arg1	pool					406:409	the primary gene pool	389:409	the primary gene pool of rice	389:417	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	8	59	theme	colour	1227:1232	arg1	gene					1240:1243	black hull colour (Bh4) gene	1216:1243	black hull colour (Bh4) gene	1216:1243	However, in contrast, black hull colour (Bh4) gene was significantly expressed throughout seed development.					
36362135	2	60	used	used	200:203	arg2	RNA-Seq					188:194	RNA-Seq	188:194	RNA-Seq	188:194	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	7	61	dep	stage	1056:1060	arg1	days					1065:1068	5 days	1063:1068	5 days post anthesis (DPA)	1063:1088	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	5	62	from	profiling	485:493	arg1	genome					526:531	the genome	522:531	the genome	522:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	63	theme	development	625:635	arg1	stages					610:615	different stages	600:615	different stages of seed development in both wild and domesticated rice	600:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	9	64	theme	starch	1387:1392	arg1	metabolism					1406:1415	starch and sucrose metabolism	1387:1415	starch and sucrose metabolism	1387:1415	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	7	65	theme	seed	1008:1011	arg1	proteins					1021:1028	seed storage proteins	1008:1028	seed storage proteins	1008:1028	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	5	66	theme	coding	502:507	arg1	sequences					509:517	all coding sequences	498:517	all coding sequences in the genome	498:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	67	from	sequences	509:517	arg1	genome					526:531	the genome	522:531	the genome	522:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	7	68	theme	seed	1141:1144	arg1	development					1146:1156	seed development	1141:1156	seed development in both wild and domesticated rice	1141:1191	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	8	69	theme	black	1216:1220	arg1	gene					1240:1243	black hull colour (Bh4) gene	1216:1243	black hull colour (Bh4) gene	1216:1243	However, in contrast, black hull colour (Bh4) gene was significantly expressed throughout seed development.					
36362135	4	70	dep	Australian	363:372	arg1	Oryza					420:424	Oryza	420:424	Oryza	420:424	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	4	70	dep	Australian	363:372	arg1	Oryza					443:447	Oryza	443:447	Oryza	443:447	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	4	70	dep	Australian	363:372	arg1	Nipponbare					343:352	Nipponbare	343:352	Nipponbare	343:352	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	4	70	dep	Australian	363:372	arg1	taxa					379:382	wild taxa	374:382	wild taxa	374:382	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	5	71	theme	Transcriptome	471:483	arg1	profiling					485:493	Transcriptome profiling	471:493	Transcriptome profiling of all coding sequences in the genome	471:531	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	9	72	theme	seed	1422:1425	arg1	proteins					1435:1442	seed storage proteins	1422:1442	seed storage proteins	1422:1442	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36362135	2	73	from	stages	262:267	arg1	rice					305:308	domesticated rice	292:308	domesticated rice	292:308	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	5	74	theme	domesticated	654:665	arg1	rice					667:670	domesticated rice	654:670	domesticated rice	654:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	4	75	theme	type	459:462	arg1	taxa					464:467	rufipogon type taxa	449:467	rufipogon type taxa	449:467	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	3	76	dep	var	338:340	arg1	japonica					329:336	japonica	329:336	japonica	329:336	japonica var.					
36362135	1	77	dep	composition	74:84	arg1	The					70:72	The	70:72	The	70:72	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	7	78	theme	domestication	951:963	arg1	traits					965:970	domestication traits	951:970	domestication traits	951:970	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	8	79	theme	Bh4	1235:1237	arg1	gene					1240:1243	black hull colour (Bh4) gene	1216:1243	black hull colour (Bh4) gene	1216:1243	However, in contrast, black hull colour (Bh4) gene was significantly expressed throughout seed development.					
36362135	2	80	dep	Oryza	311:315	arg1	sativa					317:322	Oryza sativa ssp	311:326	Oryza sativa ssp	311:326	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	2	80	dep	Oryza	311:315	arg1	ssp					324:326	ssp	324:326	Oryza sativa ssp	311:326	RNA-Seq was used to investigate the level of gene expression at different stages of seed development in domesticated rice (Oryza sativa ssp.					
36362135	1	81	from	product	129:135	arg1	seed					182:185	the developing seed	167:185	the developing seed	167:185	The composition and nutritional properties of rice are the product of the expression of genes in the developing seed.					
36362135	10	82	theme	processes	1547:1555	arg1	timing					1527:1532	the timing	1523:1532	the timing of metabolic processes associated with seed development	1523:1588	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	7	83	theme	gene	919:922	arg1	expression					924:933	gene expression	919:933	gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins	919:1028	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	7	84	theme	middle	1098:1103	arg1	stage					1105:1109	the middle stage	1094:1109	the middle stage (15 DPA)	1094:1118	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	7	84	theme	middle	1098:1103	arg1	DPA					1115:1117	15 DPA	1112:1117	15 DPA	1112:1117	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	4	85	dep	Oryza	420:424	arg1	taxa					464:467	rufipogon type taxa	449:467	rufipogon type taxa	449:467	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	4	85	dep	Oryza	420:424	arg1	meridionalis					426:437	Oryza meridionalis	420:437	Oryza meridionalis	420:437	Nipponbare) and two Australian wild taxa from the primary gene pool of rice (Oryza meridionalis and Oryza rufipogon type taxa).					
36362135	0	86	theme	Wild	42:45	arg1	Rice					64:67	Wild and Domesticated Rice	42:67	Wild and Domesticated Rice	42:67	Gene Expression in the Developing Seed of Wild and Domesticated Rice.					
36362135	6	87	theme	highest	823:829	arg1	number					831:836	the highest number	819:836	the highest number of being linked to protein synthesis and starch/sucrose metabolism	819:903	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	5	88	from	stages	610:615	arg1	wild					645:648	wild	645:648	wild	645:648	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	5	88	from	stages	610:615	arg1	rice					667:670	domesticated rice	654:670	domesticated rice	654:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	7	89	theme	domesticated	1175:1186	arg1	rice					1188:1191	both wild and domesticated rice	1161:1191	both wild and domesticated rice	1161:1191	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	5	90	from	wild	645:648	arg1	stages					610:615	different stages	600:615	different stages of seed development in both wild and domesticated rice	600:670	Transcriptome profiling of all coding sequences in the genome revealed that genes were significantly differentially expressed at different stages of seed development in both wild and domesticated rice.					
36362135	6	91	theme	signal	794:799	arg1	transduction					801:812	signal transduction	794:812	signal transduction	794:812	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	10	92	used	used	1601:1604	arg2	patterns					1465:1472	The patterns	1461:1472	The patterns of gene expression revealed in this study	1461:1514	The patterns of gene expression revealed in this study define the timing of metabolic processes associated with seed development and may be used to explain differences in rice grain quality and nutritional value.					
36362135	7	93	theme	wild	1166:1169	arg1	rice					1188:1191	both wild and domesticated rice	1161:1191	both wild and domesticated rice	1161:1191	The level of gene expression associated with domestication traits, starch and sucrose metabolism, and seed storage proteins were highest at the early stage (5 days post anthesis (DPA)) to the middle stage (15 DPA) and declined late in seed development in both wild and domesticated rice.					
36362135	6	94	theme	expressed	688:696	arg1	genes					698:702	Differentially expressed genes	673:702	Differentially expressed genes	673:702	Differentially expressed genes were associated with metabolism, transcriptional regulation, nucleic acid processing, and signal transduction with the highest number of being linked to protein synthesis and starch/sucrose metabolism.					
36362135	9	95	theme	substantial	1304:1314	arg1	number					1316:1321	A substantial number	1302:1321	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins	1302:1442	A substantial number of novel transcripts (38) corresponding to domestication genes, starch and sucrose metabolism, and seed storage proteins were identified.					
36436862	0	0	theme	ion	90:92	arg1	warehouses					95:104	renewable metal ion "warehouses	74:104	renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects	74:166	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	4	1	theme	key	716:718	arg1	"					689:689	the "warehouses"	674:689	the "warehouses" of metal ions	674:703	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	1	theme	key	716:718	arg1	CMCS					642:645	CMCS	642:645	CMCS	642:645	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	1	theme	key	716:718	arg1	roles					720:724	key roles	716:724	key roles	716:724	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	1	theme	key	716:718	arg1	MOFs					662:665	bimetallic MOFs	651:665	bimetallic MOFs	651:665	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	3	2	theme	composite	516:524	arg1	beads					526:530	renewable Ag/Cu-BTC@CMCS composite beads	491:530	renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	491:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	7	3	theme	fungicides	1540:1549	arg1	design					1491:1496	design	1491:1496	design	1491:1496	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	7	3	theme	fungicides	1540:1549	arg1	application					1513:1523	commercial application	1502:1523	commercial application	1502:1523	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	0	4	theme	metal	84:88	arg1	warehouses					95:104	renewable metal ion "warehouses	74:104	renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects	74:166	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	3	5	with	beads	526:530	arg1	sterilization					543:555	rapid sterilization	537:555	rapid sterilization	537:555	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	5	with	beads	526:530	arg1	effects					582:588	long-term antibacterial effects	558:588	long-term antibacterial effects	558:588	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	5	with	beads	526:530	arg1	biosafety					599:607	high biosafety	594:607	high biosafety	594:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	4	6	theme	metal	785:789	arg1	ions					791:794	metal ions	785:794	metal ions	785:794	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	2	7	from	bacterium	340:348	arg1	environments					359:370	water environments	353:370	water environments	353:370	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	5	8	with	beads	901:905	arg1	efficiency					931:940	high antibacterial efficiency	912:940	high antibacterial efficiency	912:940	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	9	theme	safe	1357:1360	arg1	level					1362:1366	a safe level	1355:1366	a safe level of residual heavy metals	1355:1391	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	10	theme	renewable	491:499	arg1	beads					526:530	renewable Ag/Cu-BTC@CMCS composite beads	491:530	renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	491:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	4	11	theme	ions	700:703	arg1	"					689:689	the "warehouses"	674:689	the "warehouses" of metal ions	674:703	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	11	theme	ions	700:703	arg1	roles					720:724	key roles	716:724	key roles	716:724	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	11	theme	ions	700:703	arg1	CMCS					642:645	CMCS	642:645	CMCS	642:645	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	11	theme	ions	700:703	arg1	MOFs					662:665	bimetallic MOFs	651:665	bimetallic MOFs	651:665	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	2	12	theme	antibacterial	303:315	arg1	materials					317:325	more reliable and efficient antibacterial materials	275:325	more reliable and efficient antibacterial materials	275:325	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	6	13	theme	ions	1138:1141	arg1	release					1121:1127	the rapid release	1111:1127	the rapid release of metal ions from polymer chains	1111:1161	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	6	13	theme	ions	1138:1141	arg1	release					1181:1187	the long-term release	1167:1187	the long-term release from MOFs	1167:1197	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	7	14	theme	novel	1528:1532	arg1	fungicides					1540:1549	novel water fungicides	1528:1549	novel water fungicides	1528:1549	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	3	15	theme	antibacterial	568:580	arg1	effects					582:588	long-term antibacterial effects	558:588	long-term antibacterial effects	558:588	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	6	16	theme	pool	1269:1272	arg1	water					1274:1278	the simulated swimming pool water	1246:1278	the simulated swimming pool water in 2 h	1246:1285	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	2	17	theme	efficient	293:301	arg1	materials					317:325	more reliable and efficient antibacterial materials	275:325	more reliable and efficient antibacterial materials	275:325	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	5	18	dep	concentrations	979:992	arg1	concentrations					979:992	low minimum inhibitory concentrations	956:992	low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus)	956:1054	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	18	dep	concentrations	979:992	arg1	0.16 mg/mL					1026:1035	0.16 mg/mL	1026:1035	0.16 mg/mL against S. aureus	1026:1053	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	18	dep	concentrations	979:992	arg1	0.32 mg/mL					995:1004	0.32 mg/mL	995:1004	0.32 mg/mL against E. coli	995:1020	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	19	theme	high	912:915	arg1	efficiency					931:940	high antibacterial efficiency	912:940	high antibacterial efficiency	912:940	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	20	theme	swimming	1260:1267	arg1	water					1274:1278	the simulated swimming pool water	1246:1278	the simulated swimming pool water in 2 h	1246:1285	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	4	21	theme	metal	694:698	arg1	ions					700:703	metal ions	694:703	metal ions	694:703	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	5	22	theme	Ag+	865:867	arg1	combination					850:860	the combination	846:860	the combination of Ag+ and Cu2+	846:876	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	7	23	theme	water	1534:1538	arg1	fungicides					1540:1549	novel water fungicides	1528:1549	novel water fungicides	1528:1549	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	3	24	theme	interweaving	420:431	arg1	CMCS					457:460	CMCS	457:460	CMCS	457:460	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	24	theme	interweaving	420:431	arg1	chitosan					447:454	interweaving carboxymethyl chitosan	420:454	interweaving carboxymethyl chitosan (CMCS)	420:461	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	2	25	theme	reliable	280:287	arg1	materials					317:325	more reliable and efficient antibacterial materials	275:325	more reliable and efficient antibacterial materials	275:325	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	4	26	theme	warehouses	679:688	arg1	"					689:689	the "warehouses"	674:689	the "warehouses" of metal ions	674:703	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	26	theme	warehouses	679:688	arg1	roles					720:724	key roles	716:724	key roles	716:724	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	26	theme	warehouses	679:688	arg1	CMCS					642:645	CMCS	642:645	CMCS	642:645	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	26	theme	warehouses	679:688	arg1	MOFs					662:665	bimetallic MOFs	651:665	bimetallic MOFs	651:665	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	5	27	theme	synergistic	801:811	arg1	effect					827:832	The synergistic antibacterial effect	797:832	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+	797:876	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	28	theme	heavy	1380:1384	arg1	metals					1386:1391	residual heavy metals	1371:1391	residual heavy metals	1371:1391	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	29	theme	high	594:597	arg1	biosafety					599:607	high biosafety	594:607	high biosafety	594:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	7	30	theme	new	1446:1448	arg1	insights					1450:1457	new insights	1446:1457	new insights	1446:1457	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	3	31	theme	chitosan	447:454	arg1	strategy					408:415	a novel strategy	400:415	a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	400:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	32	theme	novel	402:406	arg1	strategy					408:415	a novel strategy	400:415	a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	400:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	5	33	theme	99.9 	1065:1069	arg1	%					1070:1070	%	1070:1070	%	1070:1070	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	34	theme	polymer	1148:1154	arg1	chains					1156:1161	polymer chains	1148:1161	polymer chains	1148:1161	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	4	35	theme	controlled	763:772	arg1	release					774:780	controlled release	763:780	controlled release of metal ions	763:794	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	1	36	theme	water	203:207	arg1	environment					209:219	the water environment	199:219	the water environment	199:219	Pathogens transmitted through the water environment pose a great threat to human health.					
36436862	0	37	theme	chitosan	31:38	arg1	Hybridization					0:12	Hybridization	0:12	Hybridization of carboxymethyl chitosan with bimetallic MOFs	0:59	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	5	38	theme	antibacterial	813:825	arg1	effect					827:832	The synergistic antibacterial effect	797:832	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+	797:876	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	39	theme	composite	1204:1212	arg1	beads					1214:1218	the composite beads	1200:1218	the composite beads	1200:1218	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	5	40	theme	low	956:958	arg1	concentrations					979:992	low minimum inhibitory concentrations	956:992	low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus)	956:1054	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	40	theme	low	956:958	arg1	0.16 mg/mL					1026:1035	0.16 mg/mL	1026:1035	0.16 mg/mL against S. aureus	1026:1053	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	40	theme	low	956:958	arg1	0.32 mg/mL					995:1004	0.32 mg/mL	995:1004	0.32 mg/mL against E. coli	995:1020	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	41	theme	inhibitory	968:977	arg1	concentrations					979:992	low minimum inhibitory concentrations	956:992	low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus)	956:1054	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	41	theme	inhibitory	968:977	arg1	0.16 mg/mL					1026:1035	0.16 mg/mL	1026:1035	0.16 mg/mL against S. aureus	1026:1053	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	41	theme	inhibitory	968:977	arg1	0.32 mg/mL					995:1004	0.32 mg/mL	995:1004	0.32 mg/mL against E. coli	995:1020	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	0	42	theme	carboxymethyl	17:29	arg1	chitosan					31:38	carboxymethyl chitosan	17:38	carboxymethyl chitosan	17:38	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	0	43	theme	rapid	112:116	arg1	sterilization					118:130	rapid sterilization	112:130	rapid sterilization	112:130	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	5	44	theme	%	1070:1070	arg1	bacteria					1072:1079	99.9 % bacteria	1065:1079	99.9 % bacteria killing rate	1065:1092	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	45	theme	minimum	960:966	arg1	concentrations					979:992	low minimum inhibitory concentrations	956:992	low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus)	956:1054	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	45	theme	minimum	960:966	arg1	0.16 mg/mL					1026:1035	0.16 mg/mL	1026:1035	0.16 mg/mL against S. aureus	1026:1053	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	5	45	theme	minimum	960:966	arg1	0.32 mg/mL					995:1004	0.32 mg/mL	995:1004	0.32 mg/mL against E. coli	995:1020	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	6	46	from	chains	1156:1161	arg1	release					1121:1127	the rapid release	1111:1127	the rapid release of metal ions from polymer chains	1111:1161	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	6	46	from	chains	1156:1161	arg1	release					1181:1187	the long-term release	1167:1187	the long-term release from MOFs	1167:1197	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	0	47	theme	bimetallic	45:54	arg1	MOFs					56:59	bimetallic MOFs	45:59	bimetallic MOFs	45:59	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	5	48	theme	antibacterial	917:929	arg1	efficiency					931:940	high antibacterial efficiency	912:940	high antibacterial efficiency	912:940	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	0	49	theme	long-term	136:144	arg1	effects					160:166	long-term antibacterial effects	136:166	long-term antibacterial effects	136:166	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	3	50	theme	carboxymethyl	433:445	arg1	CMCS					457:460	CMCS	457:460	CMCS	457:460	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	50	theme	carboxymethyl	433:445	arg1	chitosan					447:454	interweaving carboxymethyl chitosan	420:454	interweaving carboxymethyl chitosan (CMCS)	420:461	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	5	51	theme	Cu2+	873:876	arg1	combination					850:860	the combination	846:860	the combination of Ag+ and Cu2+	846:876	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	7	52	dep	design	1491:1496	arg1	the					1487:1489	the	1487:1489	the	1487:1489	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	1	53	theme	great	228:232	arg1	threat					234:239	a great threat	226:239	a great threat to human health	226:255	Pathogens transmitted through the water environment pose a great threat to human health.					
36436862	6	54	theme	bacterial	1312:1320	arg1	reproduction					1322:1333	bacterial reproduction	1312:1333	bacterial reproduction	1312:1333	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	7	55	theme	commercial	1502:1511	arg1	application					1513:1523	commercial application	1502:1523	commercial application	1502:1523	This work provides new insights and promises a strategy for the design and commercial application of novel water fungicides.					
36436862	6	56	theme	CMCS	1421:1424	arg1	chelation					1408:1416	the chelation	1404:1416	the chelation of CMCS	1404:1424	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	57	theme	@	510:510	arg1	beads					526:530	renewable Ag/Cu-BTC@CMCS composite beads	491:530	renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	491:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	6	58	theme	metals	1386:1391	arg1	level					1362:1366	a safe level	1355:1366	a safe level of residual heavy metals	1355:1391	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	6	59	theme	long-term	1171:1179	arg1	release					1181:1187	the long-term release	1167:1187	the long-term release from MOFs	1167:1197	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	0	60	theme	antibacterial	146:158	arg1	effects					160:166	long-term antibacterial effects	136:166	long-term antibacterial effects	136:166	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	6	61	theme	simulated	1250:1258	arg1	water					1274:1278	the simulated swimming pool water	1246:1278	the simulated swimming pool water in 2 h	1246:1285	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	62	theme	CMCS	511:514	arg1	beads					526:530	renewable Ag/Cu-BTC@CMCS composite beads	491:530	renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	491:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	4	63	theme	ions	791:794	arg1	delivery					749:756	delivery	749:756	delivery	749:756	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	63	theme	ions	791:794	arg1	release					774:780	controlled release	763:780	controlled release of metal ions	763:794	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	63	theme	ions	791:794	arg1	storage					740:746	storage	740:746	storage	740:746	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	63	theme	ions	791:794	arg1	anchoring					729:737	anchoring	729:737	anchoring	729:737	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	0	64	with	Hybridization	0:12	arg1	MOFs					56:59	bimetallic MOFs	45:59	bimetallic MOFs	45:59	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	2	65	dep	bacterium	340:348	arg1	urgent					375:380	urgent	375:380	urgent	375:380	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	6	66	theme	rapid	1115:1119	arg1	release					1121:1127	the rapid release	1111:1127	the rapid release of metal ions from polymer chains	1111:1161	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	6	67	from	water	1274:1278	arg1	2 h					1283:1285	2 h	1283:1285	2 h	1283:1285	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	68	theme	long-term	558:566	arg1	effects					582:588	long-term antibacterial effects	558:588	long-term antibacterial effects	558:588	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	3	69	theme	Ag/Cu-BTC	501:509	arg1	beads					526:530	renewable Ag/Cu-BTC@CMCS composite beads	491:530	renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	491:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	6	70	theme	metal	1132:1136	arg1	ions					1138:1141	metal ions	1132:1141	metal ions	1132:1141	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	2	71	theme	water	353:357	arg1	environments					359:370	water environments	353:370	water environments	353:370	Hence developing more reliable and efficient antibacterial materials to eliminate bacterium in water environments is urgent.					
36436862	0	72	theme	renewable	74:82	arg1	warehouses					95:104	renewable metal ion "warehouses	74:104	renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects	74:166	Hybridization of carboxymethyl chitosan with bimetallic MOFs to construct renewable metal ion "warehouses" with rapid sterilization and long-term antibacterial effects.					
36436862	3	73	theme	Ag/Cu-MOFs	467:476	arg1	strategy					408:415	a novel strategy	400:415	a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety	400:607	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	5	74	theme	composite	891:899	arg1	beads					901:905	the composite beads	887:905	the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate	887:1092	The synergistic antibacterial effect achieved by the combination of Ag+ and Cu2+ provides the composite beads with high antibacterial efficiency, resulting in low minimum inhibitory concentrations (0.32 mg/mL against E. coli and 0.16 mg/mL against S. aureus) and over 99.9 % bacteria killing rate.					
36436862	1	75	theme	human	244:248	arg1	health					250:255	human health	244:255	human health	244:255	Pathogens transmitted through the water environment pose a great threat to human health.					
36436862	6	76	theme	residual	1371:1378	arg1	metals					1386:1391	residual heavy metals	1371:1391	residual heavy metals	1371:1391	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	3	77	theme	rapid	537:541	arg1	sterilization					543:555	rapid sterilization	537:555	rapid sterilization	537:555	Herein, we posed a novel strategy of interweaving carboxymethyl chitosan (CMCS) and Ag/Cu-MOFs to construct renewable Ag/Cu-BTC@CMCS composite beads with rapid sterilization, long-term antibacterial effects and high biosafety.					
36436862	6	78	from	MOFs	1194:1197	arg1	release					1121:1127	the rapid release	1111:1127	the rapid release of metal ions from polymer chains	1111:1161	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	6	78	from	MOFs	1194:1197	arg1	release					1181:1187	the long-term release	1167:1187	the long-term release from MOFs	1167:1197	Benefiting from the rapid release of metal ions from polymer chains and the long-term release from MOFs, the composite beads can effectively sterilize the simulated swimming pool water in 2 h and persistently inhibit bacterial reproduction over 48 h, and show a safe level of residual heavy metals because of the chelation of CMCS.					
36436862	4	79	theme	bimetallic	651:660	arg1	"					689:689	the "warehouses"	674:689	the "warehouses" of metal ions	674:703	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	79	theme	bimetallic	651:660	arg1	roles					720:724	key roles	716:724	key roles	716:724	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	79	theme	bimetallic	651:660	arg1	CMCS					642:645	CMCS	642:645	CMCS	642:645	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36436862	4	79	theme	bimetallic	651:660	arg1	MOFs					662:665	bimetallic MOFs	651:665	bimetallic MOFs	651:665	Characterizations revealed that CMCS and bimetallic MOFs act as the "warehouses" of metal ions and played key roles in anchoring, storage, delivery, and controlled release of metal ions.					
36972821	4	0	theme	XRD	743:745	arg1	Characterization					709:724	Characterization	709:724	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS	709:760	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	2	1	theme	As	517:518	arg1	removal					525:531	As(III) removal	517:531	As(III) removal	517:531	However, GOCS is often inefficient for heavy metal adsorption and FMBO suffers poor regeneration for As(III) removal.					
36972821	3	2	theme	FMBO	586:589	arg1	method					568:573	a method	566:573	a method of dopping FMBO into GOCS	566:599	In this study, we have proposed a method of dopping FMBO into GOCS to obtain a recyclable granular adsorbent (Fe/MnGOCS) for achieving As(III) removal from aqueous solutions.					
36972821	4	3	dep	mechanism	836:844	arg1	III					823:825	III	823:825	III	823:825	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	7	4	theme	GOCS	1577:1580	arg1	GOCS					1577:1580	GOCS	1577:1580	GOCS	1577:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	4	theme	GOCS	1577:1580	arg1	groups					1567:1572	oxygen-containing functional groups	1538:1572	oxygen-containing functional groups of GOCS	1538:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	4	5	theme	FTIR	748:751	arg1	Characterization					709:724	Characterization	709:724	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS	709:760	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	5	6	theme	processes	1016:1024	arg1	effects					898:904	the effects	894:904	the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes	894:1024	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	4	7	theme	BET	729:731	arg1	Characterization					709:724	Characterization	709:724	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS	709:760	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	8	8	theme	pH	1700:1701	arg1	values					1703:1708	pH values	1700:1708	pH values of 3-10	1700:1716	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	7	9	dep	solutions	1425:1433	arg1	III					1407:1409	III	1407:1409	III	1407:1409	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	1	10	theme	III	410:412	arg1	capacity					395:402	their high removal capacity	376:402	their high removal capacity of As(III)	376:413	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	7	11	theme	oxygen-containing	1538:1554	arg1	GOCS					1577:1580	GOCS	1577:1580	GOCS	1577:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	11	theme	oxygen-containing	1538:1554	arg1	groups					1567:1572	oxygen-containing functional groups	1538:1572	oxygen-containing functional groups of GOCS	1538:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	12	theme	major	1378:1382	arg1	complexation					1345:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation	1281:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III)	1281:1369	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	12	theme	major	1378:1382	arg1	mechanism					1384:1392	the major mechanism	1374:1392	the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS	1374:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	0	13	theme	graphene	92:99	arg1	chitosan					107:114	graphene oxide chitosan	92:114	graphene oxide chitosan	92:114	As(III) removal by a recyclable granular adsorbent through dopping Fe-Mn binary oxides into graphene oxide chitosan.					
36972821	7	14	theme	amorphous	1281:1289	arg1	complexation					1345:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation	1281:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III)	1281:1369	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	14	theme	amorphous	1281:1289	arg1	mechanism					1384:1392	the major mechanism	1374:1392	the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS	1374:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	14	15	theme	binary	2269:2274	arg1	composite					2284:2292	binary polymer composite	2269:2292	binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments	2269:2385	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	3	16	dep	removal	677:683	arg1	III					672:674	III	672:674	III	672:674	In this study, we have proposed a method of dopping FMBO into GOCS to obtain a recyclable granular adsorbent (Fe/MnGOCS) for achieving As(III) removal from aqueous solutions.					
36972821	1	17	theme	environmentally	178:192	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	17	theme	environmentally	178:192	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	17	theme	environmentally	178:192	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	10	18	theme	kinetic	1835:1841	arg1	process					1843:1849	its kinetic process	1831:1849	its kinetic process	1831:1849	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	5	19	theme	kinetic	977:983	arg1	processes					1016:1024	kinetic, isothermal, and thermodynamic processes	977:1024	kinetic, isothermal, and thermodynamic processes	977:1024	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	7	20	with	oxidation	1469:1477	arg1	GOCS					1577:1580	GOCS	1577:1580	GOCS	1577:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	20	with	oxidation	1469:1477	arg1	groups					1567:1572	oxygen-containing functional groups	1538:1572	oxygen-containing functional groups of GOCS	1538:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	14	21	theme	heavy	2348:2352	arg1	metals					2354:2359	heavy metals	2348:2359	heavy metals	2348:2359	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	7	22	dep	form	1323:1326	arg1	mainly					1309:1314	mainly	1309:1314	mainly	1309:1314	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	1	23	theme	high	382:385	arg1	capacity					395:402	their high removal capacity	376:402	their high removal capacity of As(III)	376:413	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	6	24	theme	molar	1239:1243	arg1	ratio					1245:1249	the increasing molar ratio	1224:1249	the increasing molar ratio of Mn and Fe	1224:1262	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	4	25	theme	As	820:821	arg1	mechanism					836:844	As(III) removal mechanism	820:844	As(III) removal mechanism	820:844	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	11	26	theme	Langmuir	1944:1951	arg1	isotherm					1953:1960	the Langmuir isotherm	1940:1960	the Langmuir isotherm	1940:1960	Fitted by the Langmuir isotherm, the maximum adsorption capacity is 108.89 mg/g at 25 °C.					
36972821	9	27	theme	coexisting	1727:1736	arg1	PO43-					1738:1742	the coexisting PO43-	1723:1742	the coexisting PO43-	1723:1742	But the coexisting PO43- can greatly decrease Re by 24.11 %.					
36972821	5	28	theme	thermodynamic	1002:1014	arg1	processes					1016:1024	kinetic, isothermal, and thermodynamic processes	977:1024	kinetic, isothermal, and thermodynamic processes	977:1024	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	29	theme	coexisting	942:951	arg1	ions					953:956	coexisting ions	942:956	coexisting ions	942:956	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	29	theme	coexisting	942:951	arg1	pH					930:931	pH	930:931	pH	930:931	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	1	30	theme	oxide	126:130	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	30	theme	oxide	126:130	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	30	theme	oxide	126:130	arg1	GOCS					152:155	GOCS	152:155	GOCS	152:155	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	30	theme	oxide	126:130	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	4	31	theme	removal	828:834	arg1	mechanism					836:844	As(III) removal mechanism	820:844	As(III) removal mechanism	820:844	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	11	32	theme	maximum	1967:1973	arg1	capacity					1986:1993	the maximum adsorption capacity	1963:1993	the maximum adsorption capacity	1963:1993	Fitted by the Langmuir isotherm, the maximum adsorption capacity is 108.89 mg/g at 25 °C.					
36972821	2	33	theme	poor	495:498	arg1	regeneration					500:511	poor regeneration	495:511	poor regeneration	495:511	However, GOCS is often inefficient for heavy metal adsorption and FMBO suffers poor regeneration for As(III) removal.					
36972821	13	34	theme	adsorption	2117:2126	arg1	experiments					2128:2138	Column adsorption experiments	2110:2138	Column adsorption experiments	2110:2138	Column adsorption experiments show that Fe/MnGOCS can effectively reduce As(III) concentration from 10 mg/L to <10 μg/L.					
36972821	1	35	theme	binary	313:318	arg1	FMBO					328:331	FMBO	328:331	FMBO	328:331	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	35	theme	binary	313:318	arg1	oxides					320:325	Fe-Mn binary oxides	307:325	Fe-Mn binary oxides (FMBO)	307:332	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	36	theme	composite	141:149	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	36	theme	composite	141:149	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	36	theme	composite	141:149	arg1	GOCS					152:155	GOCS	152:155	GOCS	152:155	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	36	theme	composite	141:149	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	2	37	theme	metal	461:465	arg1	adsorption					467:476	heavy metal adsorption	455:476	heavy metal adsorption	455:476	However, GOCS is often inefficient for heavy metal adsorption and FMBO suffers poor regeneration for As(III) removal.					
36972821	7	38	with	complexation	1345:1356	arg1	As					1363:1364	As	1363:1364	As	1363:1364	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	38	with	complexation	1345:1356	arg1	III					1366:1368	III	1366:1368	III	1366:1368	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	12	39	theme	slight	2067:2072	arg1	decrease					2074:2081	only a slight decrease	2060:2081	only a slight decrease of <10 % for the Re value	2060:2107	After four times regeneration, there is only a slight decrease of <10 % for the Re value.					
36972821	3	40	theme	aqueous	690:696	arg1	solutions					698:706	aqueous solutions	690:706	aqueous solutions	690:706	In this study, we have proposed a method of dopping FMBO into GOCS to obtain a recyclable granular adsorbent (Fe/MnGOCS) for achieving As(III) removal from aqueous solutions.					
36972821	0	41	theme	Fe-Mn	67:71	arg1	oxides					80:85	Fe-Mn binary oxides	67:85	Fe-Mn binary oxides	67:85	As(III) removal by a recyclable granular adsorbent through dopping Fe-Mn binary oxides into graphene oxide chitosan.					
36972821	4	42	theme	Fe/MnGOCS	806:814	arg1	mechanism					836:844	As(III) removal mechanism	820:844	As(III) removal mechanism	820:844	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	4	42	theme	Fe/MnGOCS	806:814	arg1	formation					793:801	the formation	789:801	the formation of Fe/MnGOCS	789:814	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	7	43	theme	Mn	1491:1492	arg1	oxides					1494:1499	Mn oxides	1491:1499	Mn oxides	1491:1499	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	8	44	theme	weaker	1610:1615	arg1	role					1617:1620	a weaker role	1608:1620	a weaker role	1608:1620	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	13	45	dep	concentration	2191:2203	arg1	III					2186:2188	III	2186:2188	III	2186:2188	Column adsorption experiments show that Fe/MnGOCS can effectively reduce As(III) concentration from 10 mg/L to <10 μg/L.					
36972821	1	46	theme	abundant	252:259	arg1	groups					272:277	abundant functional groups	252:277	abundant functional groups	252:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	7	47	theme	oxides	1301:1306	arg1	complexation					1345:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation	1281:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III)	1281:1369	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	47	theme	oxides	1301:1306	arg1	mechanism					1384:1392	the major mechanism	1374:1392	the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS	1374:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	12	48	theme	%	2090:2090	arg1	decrease					2074:2081	only a slight decrease	2060:2081	only a slight decrease of <10 % for the Re value	2060:2107	After four times regeneration, there is only a slight decrease of <10 % for the Re value.					
36972821	1	49	theme	groups	272:277	arg1	adsorbent					213:221	adsorbent	213:221	adsorbent	213:221	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	14	50	theme	metal	2313:2317	arg1	oxides					2319:2324	binary metal oxides	2306:2324	binary metal oxides	2306:2324	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	7	51	theme	hydro	1295:1299	arg1	complexation					1345:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation	1281:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III)	1281:1369	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	51	theme	hydro	1295:1299	arg1	mechanism					1384:1392	the major mechanism	1374:1392	the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS	1374:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	52	dep	oxidation	1469:1477	arg1	III					1464:1466	III	1464:1466	III	1464:1466	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	8	53	theme	Charge	1583:1588	arg1	interaction					1590:1600	Charge interaction	1583:1600	Charge interaction	1583:1600	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	0	54	dep	removal	8:14	arg1	III					3:5	III	3:5	III	3:5	As(III) removal by a recyclable granular adsorbent through dopping Fe-Mn binary oxides into graphene oxide chitosan.					
36972821	7	55	theme	aqueous	1417:1423	arg1	solutions					1425:1433	aqueous solutions	1417:1433	aqueous solutions	1417:1433	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	12	56	theme	times	2031:2035	arg1	regeneration					2037:2048	four times regeneration	2026:2048	four times regeneration	2026:2048	After four times regeneration, there is only a slight decrease of <10 % for the Re value.					
36972821	3	57	theme	dopping	578:584	arg1	FMBO					586:589	dopping FMBO	578:589	dopping FMBO	578:589	In this study, we have proposed a method of dopping FMBO into GOCS to obtain a recyclable granular adsorbent (Fe/MnGOCS) for achieving As(III) removal from aqueous solutions.					
36972821	1	58	theme	friendly	194:201	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	58	theme	friendly	194:201	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	58	theme	friendly	194:201	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	14	59	theme	binary	2306:2311	arg1	oxides					2319:2324	binary metal oxides	2306:2324	binary metal oxides	2306:2324	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	10	60	from	adsorption	1788:1797	arg1	Fe/MnGOCS					1802:1810	Fe/MnGOCS	1802:1810	Fe/MnGOCS	1802:1810	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	1	61	theme	adsorbent	213:221	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	61	theme	adsorbent	213:221	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	61	theme	adsorbent	213:221	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	10	62	dep	endothermic	1815:1825	arg1	As					1780:1781	As	1780:1781	As	1780:1781	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	1	63	theme	stability	238:246	arg1	adsorbent					213:221	adsorbent	213:221	adsorbent	213:221	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	10	64	dep	adsorption	1788:1797	arg1	III					1783:1785	III	1783:1785	III	1783:1785	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	8	65	theme	wide	1686:1689	arg1	range					1691:1695	a wide range	1684:1695	a wide range of pH values of 3-10	1684:1716	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	7	66	from	complexation	1345:1356	arg1	form					1323:1326	the form	1319:1326	the form of ferrihydrite	1319:1342	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	14	67	theme	polymer	2276:2282	arg1	composite					2284:2292	binary polymer composite	2269:2292	binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments	2269:2385	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	6	68	theme	removal	1049:1055	arg1	efficiency					1057:1066	the removal efficiency	1045:1066	the removal efficiency (Re) of As(III) by Fe/MnGOCS	1045:1095	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	6	68	theme	removal	1049:1055	arg1	%					1109:1109	about 96 %	1100:1109	about 96 %	1100:1109	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	6	68	theme	removal	1049:1055	arg1	Re					1069:1070	Re	1069:1070	Re	1069:1070	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	7	69	theme	functional	1556:1565	arg1	GOCS					1577:1580	GOCS	1577:1580	GOCS	1577:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	69	theme	functional	1556:1565	arg1	groups					1567:1572	oxygen-containing functional groups	1538:1572	oxygen-containing functional groups of GOCS	1538:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	70	theme	Fe	1291:1292	arg1	complexation					1345:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation	1281:1356	amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III)	1281:1369	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	70	theme	Fe	1291:1292	arg1	mechanism					1384:1392	the major mechanism	1374:1392	the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS	1374:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	8	71	theme	values	1703:1708	arg1	range					1691:1695	a wide range	1684:1695	a wide range of pH values of 3-10	1684:1716	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	0	72	theme	oxide	101:105	arg1	chitosan					107:114	graphene oxide chitosan	92:114	graphene oxide chitosan	92:114	As(III) removal by a recyclable granular adsorbent through dopping Fe-Mn binary oxides into graphene oxide chitosan.					
36972821	8	73	theme	3-10	1713:1716	arg1	values					1703:1708	pH values	1700:1708	pH values of 3-10	1700:1716	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	14	74	theme	aquatic	2366:2372	arg1	environments					2374:2385	aquatic environments	2366:2385	aquatic environments	2366:2385	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	5	75	theme	operational	909:919	arg1	factors					921:927	operational factors	909:927	operational factors (pH, dosage, coexisting ions, etc.)	909:963	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	7	76	theme	III	1528:1530	arg1	oxidation					1469:1477	oxidation	1469:1477	As(III) oxidation mediated by Mn oxides	1461:1499	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	76	theme	III	1528:1530	arg1	complexation					1509:1520	the complexation	1505:1520	the complexation of As(III) with oxygen-containing functional groups of GOCS	1505:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	10	77	theme	determination	1895:1907	arg1	coefficient					1909:1919	a determination coefficient	1893:1919	a determination coefficient of 0.95	1893:1927	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	8	78	dep	high	1674:1677	arg1	III					1628:1630	III	1628:1630	III	1628:1630	Charge interaction plays a weaker role in As(III) adsorption, therefore Re is persistently high over a wide range of pH values of 3-10.					
36972821	6	79	theme	Mn	1254:1255	arg1	ratio					1245:1249	the increasing molar ratio	1224:1249	the increasing molar ratio of Mn and Fe	1224:1262	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	14	80	theme	new	2251:2253	arg1	insights					2255:2262	new insights	2251:2262	new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments	2251:2385	This study provides new insights into binary polymer composite modified by binary metal oxides to efficiently remove heavy metals from aquatic environments.					
36972821	6	81	theme	III	1079:1081	arg1	efficiency					1057:1066	the removal efficiency	1045:1066	the removal efficiency (Re) of As(III) by Fe/MnGOCS	1045:1095	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	6	81	theme	III	1079:1081	arg1	%					1109:1109	about 96 %	1100:1109	about 96 %	1100:1109	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	6	81	theme	III	1079:1081	arg1	Re					1069:1070	Re	1069:1070	Re	1069:1070	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	4	82	theme	XPS	758:760	arg1	Characterization					709:724	Characterization	709:724	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS	709:760	Characterization of BET, SEM-EDS, XRD, FTIR, and XPS are carried out to confirm the formation of Fe/MnGOCS and As(III) removal mechanism.					
36972821	1	83	theme	removal	387:393	arg1	capacity					395:402	their high removal capacity	376:402	their high removal capacity of As(III)	376:413	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	6	84	theme	increasing	1228:1237	arg1	ratio					1245:1249	the increasing molar ratio	1224:1249	the increasing molar ratio of Mn and Fe	1224:1262	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	1	85	theme	Graphene	117:124	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	85	theme	Graphene	117:124	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	85	theme	Graphene	117:124	arg1	GOCS					152:155	GOCS	152:155	GOCS	152:155	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	85	theme	Graphene	117:124	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	12	86	theme	Re	2100:2101	arg1	value					2103:2107	the Re value	2096:2107	the Re value	2096:2107	After four times regeneration, there is only a slight decrease of <10 % for the Re value.					
36972821	13	87	theme	Column	2110:2115	arg1	experiments					2128:2138	Column adsorption experiments	2110:2138	Column adsorption experiments	2110:2138	Column adsorption experiments show that Fe/MnGOCS can effectively reduce As(III) concentration from 10 mg/L to <10 μg/L.					
36972821	1	88	theme	Fe-Mn	307:311	arg1	FMBO					328:331	FMBO	328:331	FMBO	328:331	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	88	theme	Fe-Mn	307:311	arg1	oxides					320:325	Fe-Mn binary oxides	307:325	Fe-Mn binary oxides (FMBO)	307:332	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	7	89	with	complexation	1509:1520	arg1	GOCS					1577:1580	GOCS	1577:1580	GOCS	1577:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	7	89	with	complexation	1509:1520	arg1	groups					1567:1572	oxygen-containing functional groups	1538:1572	oxygen-containing functional groups of GOCS	1538:1580	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	0	90	theme	binary	73:78	arg1	oxides					80:85	Fe-Mn binary oxides	67:85	Fe-Mn binary oxides	67:85	As(III) removal by a recyclable granular adsorbent through dopping Fe-Mn binary oxides into graphene oxide chitosan.					
36972821	7	91	theme	ferrihydrite	1331:1342	arg1	form					1323:1326	the form	1319:1326	the form of ferrihydrite	1319:1342	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	2	92	theme	heavy	455:459	arg1	adsorption					467:476	heavy metal adsorption	455:476	heavy metal adsorption	455:476	However, GOCS is often inefficient for heavy metal adsorption and FMBO suffers poor regeneration for As(III) removal.					
36972821	11	93	theme	adsorption	1975:1984	arg1	capacity					1986:1993	the maximum adsorption capacity	1963:1993	the maximum adsorption capacity	1963:1993	Fitted by the Langmuir isotherm, the maximum adsorption capacity is 108.89 mg/g at 25 °C.					
36972821	10	94	with	pseudo-second-order	1868:1886	arg1	coefficient					1909:1919	a determination coefficient	1893:1919	a determination coefficient of 0.95	1893:1927	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	10	95	theme	0.95	1924:1927	arg1	coefficient					1909:1919	a determination coefficient	1893:1919	a determination coefficient of 0.95	1893:1927	As(III) adsorption on Fe/MnGOCS is endothermic and its kinetic process is controlled by pseudo-second-order with a determination coefficient of 0.95.					
36972821	1	96	theme	increasing	349:358	arg1	interest					360:367	increasing interest	349:367	increasing interest	349:367	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	96	theme	increasing	349:358	arg1	chitosan					132:139	Graphene oxide chitosan composite	117:149	Graphene oxide chitosan composite (GOCS)	117:156	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	96	theme	increasing	349:358	arg1	composite					203:211	an environmentally friendly composite	175:211	an environmentally friendly composite adsorbent because of its stability and abundant functional groups	175:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	1	97	theme	functional	261:270	arg1	groups					272:277	abundant functional groups	252:277	abundant functional groups	252:277	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	6	98	theme	Fe	1261:1262	arg1	ratio					1245:1249	the increasing molar ratio	1224:1249	the increasing molar ratio of Mn and Fe	1224:1262	Results show that the removal efficiency (Re) of As(III) by Fe/MnGOCS is about 96 %, which is much higher than those of FeGOCS (66 %), MnGOCS (42 %), and GOCS (8 %), and it increases slightly with the increasing molar ratio of Mn and Fe.					
36972821	3	99	from	solutions	698:706	arg1	removal					677:683	(III) removal	671:683	(III) removal from aqueous solutions	671:706	In this study, we have proposed a method of dopping FMBO into GOCS to obtain a recyclable granular adsorbent (Fe/MnGOCS) for achieving As(III) removal from aqueous solutions.					
36972821	5	100	theme	isothermal	986:995	arg1	processes					1016:1024	kinetic, isothermal, and thermodynamic processes	977:1024	kinetic, isothermal, and thermodynamic processes	977:1024	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	7	101	theme	As	1461:1462	arg1	oxidation					1469:1477	oxidation	1469:1477	As(III) oxidation mediated by Mn oxides	1461:1499	This is because amorphous Fe (hydro)oxides (mainly in the form of ferrihydrite) complexation with As(III) is the major mechanism to remove As(III) from aqueous solutions, and it is accompanied by As(III) oxidation mediated by Mn oxides and the complexation of As(III) with oxygen-containing functional groups of GOCS.					
36972821	5	102	theme	Batch	847:851	arg1	experiments					853:863	Batch experiments	847:863	Batch experiments	847:863	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	1	103	theme	heavy	289:293	arg1	metals					295:300	heavy metals	289:300	heavy metals	289:300	Graphene oxide chitosan composite (GOCS) is recognized as an environmentally friendly composite adsorbent because of its stability and abundant functional groups to adsorb heavy metals, and Fe-Mn binary oxides (FMBO) have attracted increasing interest due to their high removal capacity of As(III).					
36972821	5	104	theme	factors	921:927	arg1	effects					898:904	the effects	894:904	the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes	894:1024	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	105	dep	factors	921:927	arg1	dosage					934:939	dosage	934:939	dosage	934:939	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	105	dep	factors	921:927	arg1	ions					953:956	coexisting ions	942:956	coexisting ions	942:956	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	105	dep	factors	921:927	arg1	pH					930:931	pH	930:931	pH	930:931	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
36972821	5	105	dep	factors	921:927	arg1	etc.					959:962	etc.	959:962	etc.	959:962	Batch experiments are conducted to investigate the effects of operational factors (pH, dosage, coexisting ions, etc.), as well as kinetic, isothermal, and thermodynamic processes.					
35217259	2	0	theme	excessive	603:611	arg1	flow					613:616	an excessive flow	600:616	an excessive flow of fatty acids into hepatocytes	600:648	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	1	1	dep	"	435:435	arg1	HepG2					487:491	HepG2	487:491	HepG2	487:491	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	0	2	theme	fatty	171:175	arg1	disease					183:189	non-alcoholic fatty liver disease	157:189	non-alcoholic fatty liver disease	157:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	3	theme	non-alcoholic	441:453	arg1	disease					467:473	non-alcoholic fatty liver disease	441:473	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	4	theme	cells	1431:1435	arg1	medium					1391:1396	the culture medium	1379:1396	the culture medium of healthy and the disease model cells	1379:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	1	5	theme	acetate	268:274	arg1	pH 4.3					299:304	sodium acetate background electrolyte pH 4.3	261:304	sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	261:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	6	theme	intermediate	1056:1067	arg1	precision					1069:1077	intermediate precision	1056:1077	intermediate precision	1056:1077	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	0	7	from	model	148:152	arg1	investigation					71:83	the investigation	67:83	the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease	67:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	0	8	theme	disease	183:189	arg1	model					148:152	a cellular model	137:152	a cellular model of non-alcoholic fatty liver disease	137:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	9	theme	liver	461:465	arg1	disease					467:473	non-alcoholic fatty liver disease	441:473	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	10	theme	electrolyte	287:297	arg1	pH 4.3					299:304	sodium acetate background electrolyte pH 4.3	261:304	sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	261:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	2	11	theme	acids	627:631	arg1	flow					613:616	an excessive flow	600:616	an excessive flow of fatty acids into hepatocytes	600:648	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	3	12	theme	disease	698:704	arg1	pathophysiology					706:720	the disease pathophysiology	694:720	the disease pathophysiology	694:720	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	4	13	dep	range	1031:1035	arg1	limits					1217:1222	limits	1217:1222	limits	1217:1222	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	1	14	theme	model	475:479	arg1	cells					481:485	non-alcoholic fatty liver disease model cells	441:485	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	15	theme	migration	1097:1105	arg1	times					1107:1111	migration times	1097:1111	migration times	1097:1111	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	3	16	theme	intracellular	729:741	arg1	levels					783:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	0	17	theme	culture	119:125	arg1	medium					127:132	the culture medium	115:132	the culture medium	115:132	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	2	18	theme	exposure	541:548	arg1	cells					556:560	exposure HepG2 cells	541:560	exposure HepG2 cells with oleate and palmitate	541:586	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	1	19	theme	metabolism	413:422	arg1	study					404:408	the comparative study	388:408	the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2	388:491	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	20	dep	accuracy	1114:1121	arg1	trueness					1142:1149	trueness	1142:1149	trueness	1142:1149	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	20	dep	accuracy	1114:1121	arg1	rate					1133:1136	recovery rate	1124:1136	recovery rate	1124:1136	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	1	21	theme	CuSO4	207:211	arg1	additives					248:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives	207:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	207:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	22	located	found	1518:1522	arg2	acid					1503:1506	lactic acid	1496:1506	lactic acid	1496:1506	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	22	located	found	1518:1522	arg2	Ala					1478:1480	Ala	1478:1480	Ala	1478:1480	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	22	located	found	1518:1522	arg2	levels					1463:1468	altered levels	1455:1468	altered levels of Arg	1455:1475	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	22	located	found	1518:1522	arg1	comparison					1527:1536	comparison	1527:1536	comparison to health control	1527:1554	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	22	located	found	1518:1522	arg2	Glu					1483:1485	Glu	1483:1485	Glu	1483:1485	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	22	located	found	1518:1522	arg2	Gln					1488:1490	Gln	1488:1490	Gln	1488:1490	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	4	23	theme	acids	893:897	arg1	metabolism					873:882	the metabolism	869:882	the metabolism of amino acids	869:897	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	3	24	theme	interleukin	769:779	arg1	levels					783:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	0	25	theme	cellular	139:146	arg1	model					148:152	a cellular model	137:152	a cellular model of non-alcoholic fatty liver disease	137:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	6	26	theme	acids	1370:1374	arg1	concentrations					1346:1359	The concentrations	1342:1359	The concentrations of amino acids in the culture medium of healthy and the disease model cells	1342:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	27	theme	healthy	1401:1407	arg1	cells					1431:1435	healthy and the disease model cells	1401:1435	healthy and the disease model cells	1401:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	1	28	theme	acid	367:370	arg1	determination					327:339	the simultaneous determination	310:339	the simultaneous determination of amino acids and lactic acid	310:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	0	29	theme	acids	94:98	arg1	composition					100:110	amino acids composition	88:110	amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease	88:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	2	30	theme	disease	516:522	arg1	model					503:507	In vitro model	494:507	In vitro model of the disease	494:522	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	5	31	theme	acids	1319:1323	arg1	quantitation					1297:1308	the quantitation	1293:1308	the quantitation of amino acids and lactic acid	1293:1339	The method proved to be sensitive, reliable and highly accurate for the quantitation of amino acids and lactic acid.					
35217259	6	32	from	concentrations	1346:1359	arg1	medium					1391:1396	the culture medium	1379:1396	the culture medium of healthy and the disease model cells	1379:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	4	33	theme	dynamic	1023:1029	arg1	range					1031:1035	linear dynamic range	1016:1035	linear dynamic range	1016:1035	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	5	34	theme	lactic	1329:1334	arg1	acid					1336:1339	lactic acid	1329:1339	lactic acid	1329:1339	The method proved to be sensitive, reliable and highly accurate for the quantitation of amino acids and lactic acid.					
35217259	0	35	theme	Cu2+	8:11	arg1	ions					13:16	Cu2+ ions	8:16	Cu2+ ions	8:16	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	36	with	method	195:200	arg1	additives					248:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives	207:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	207:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	37	theme	amino	344:348	arg1	acids					350:354	amino acids	344:354	amino acids	344:354	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	2	38	dep	In	494:495	arg1	vitro					497:501	vitro	497:501	vitro	497:501	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	4	39	theme	peak	1082:1085	arg1	areas					1087:1091	peak areas	1082:1091	peak areas	1082:1091	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	0	40	with	CE	0:1	arg1	ions					13:16	Cu2+ ions	8:16	Cu2+ ions	8:16	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	0	40	with	CE	0:1	arg1	additives					53:61	2-hydroxypropyl-β-cyclodextrin additives	22:61	2-hydroxypropyl-β-cyclodextrin additives	22:61	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	41	from	cells	481:485	arg1	study					404:408	the comparative study	388:408	the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2	388:491	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	42	theme	amino	1364:1368	arg1	acids					1370:1374	amino acids	1364:1374	amino acids in the culture medium of healthy and the disease model cells	1364:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	0	43	theme	liver	177:181	arg1	disease					183:189	non-alcoholic fatty liver disease	157:189	non-alcoholic fatty liver disease	157:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	3	44	with	consistent	678:687	arg1	pathophysiology					706:720	the disease pathophysiology	694:720	the disease pathophysiology	694:720	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	1	45	theme	sodium	261:266	arg1	pH 4.3					299:304	sodium acetate background electrolyte pH 4.3	261:304	sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	261:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	46	theme	fatty	455:459	arg1	disease					467:473	non-alcoholic fatty liver disease	441:473	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	47	theme	model	1425:1429	arg1	cells					1431:1435	healthy and the disease model cells	1401:1435	healthy and the disease model cells	1401:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	1	48	theme	background	276:285	arg1	pH 4.3					299:304	sodium acetate background electrolyte pH 4.3	261:304	sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	261:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	49	theme	recovery	1124:1131	arg1	rate					1133:1136	recovery rate	1124:1136	recovery rate	1124:1136	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	1	50	theme	disease	467:473	arg1	cells					481:485	non-alcoholic fatty liver disease model cells	441:485	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	2	51	theme	fatty	621:625	arg1	acids					627:631	fatty acids	621:631	fatty acids	621:631	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	4	52	theme	times	1107:1111	arg1	quantitation					1204:1215	quantitation	1204:1215	quantitation	1204:1215	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	52	theme	times	1107:1111	arg1	repeatability					1038:1050	repeatability	1038:1050	repeatability	1038:1050	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	52	theme	times	1107:1111	arg1	precision					1069:1077	intermediate precision	1056:1077	intermediate precision	1056:1077	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	52	theme	times	1107:1111	arg1	accuracy					1114:1121	accuracy	1114:1121	accuracy (recovery rate and trueness estimated by reference method)	1114:1180	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	52	theme	times	1107:1111	arg1	range					1031:1035	linear dynamic range	1016:1035	linear dynamic range	1016:1035	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	52	theme	times	1107:1111	arg1	limits					1193:1198	detection limits	1183:1198	detection limits	1183:1198	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	3	53	theme	cytokine	760:767	arg1	interleukin					769:779	cytokine interleukin 8	760:781	cytokine interleukin 8	760:781	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	0	54	theme	medium	127:132	arg1	composition					100:110	amino acids composition	88:110	amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease	88:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	55	theme	CE	192:193	arg1	method					195:200	CE method	192:200	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	192:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	2	56	theme	HepG2	550:554	arg1	cells					556:560	exposure HepG2 cells	541:560	exposure HepG2 cells with oleate and palmitate	541:586	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	3	57	theme	triglyceride	743:754	arg1	levels					783:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	intracellular triglyceride and cytokine interleukin 8 levels	729:788	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	6	58	theme	Arg	1473:1475	arg1	Ala					1478:1480	Ala	1478:1480	Ala	1478:1480	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	58	theme	Arg	1473:1475	arg1	Gln					1488:1490	Gln	1488:1490	Gln	1488:1490	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	58	theme	Arg	1473:1475	arg1	levels					1463:1468	altered levels	1455:1468	altered levels of Arg	1455:1475	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	58	theme	Arg	1473:1475	arg1	acid					1503:1506	lactic acid	1496:1506	lactic acid	1496:1506	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	58	theme	Arg	1473:1475	arg1	Glu					1483:1485	Glu	1483:1485	Glu	1483:1485	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	0	59	from	investigation	71:83	arg1	model					148:152	a cellular model	137:152	a cellular model of non-alcoholic fatty liver disease	137:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	60	from	metabolism	413:422	arg1	cells					481:485	non-alcoholic fatty liver disease model cells	441:485	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	60	from	metabolism	413:422	arg1	"					435:435	"healthy"	427:435	"healthy"	427:435	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	61	from	additives	248:256	arg1	pH 4.3					299:304	sodium acetate background electrolyte pH 4.3	261:304	sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	261:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	62	theme	amino	887:891	arg1	acids					893:897	amino acids	887:897	amino acids	887:897	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	63	theme	detection	1183:1191	arg1	limits					1193:1198	detection limits	1183:1198	detection limits	1183:1198	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	0	64	theme	non-alcoholic	157:169	arg1	disease					183:189	non-alcoholic fatty liver disease	157:189	non-alcoholic fatty liver disease	157:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	65	theme	healthy	428:434	arg1	"					435:435	"healthy"	427:435	"healthy"	427:435	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	0	66	from	composition	100:110	arg1	model					148:152	a cellular model	137:152	a cellular model of non-alcoholic fatty liver disease	137:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	3	67	theme	cells	812:816	arg1	viability					818:826	cells viability	812:826	cells viability	812:826	The model was proven to be consistent with the disease pathophysiology, since intracellular triglyceride and cytokine interleukin 8 levels were increased, while cells viability was decreased.					
35217259	1	68	from	"	435:435	arg1	study					404:408	the comparative study	388:408	the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2	388:491	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	69	from	medium	1391:1396	arg1	concentrations					1346:1359	The concentrations	1342:1359	The concentrations of amino acids in the culture medium of healthy and the disease model cells	1342:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	4	70	theme	medium	963:968	arg1	preparation					940:950	sample preparation	933:950	sample preparation of culture medium	933:968	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	71	theme	reference	1164:1172	arg1	method					1174:1179	reference method	1164:1179	reference method	1164:1179	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	0	72	theme	amino	88:92	arg1	acids					94:98	amino acids	88:98	amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease	88:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	73	theme	lactic	360:365	arg1	acid					367:370	lactic acid	360:370	lactic acid	360:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	74	theme	lactic	1496:1501	arg1	levels					1463:1468	altered levels	1455:1468	altered levels of Arg	1455:1475	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	74	theme	lactic	1496:1501	arg1	acid					1503:1506	lactic acid	1496:1506	lactic acid	1496:1506	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	2	75	theme	In	494:495	arg1	model					503:507	In vitro model	494:507	In vitro model of the disease	494:522	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	0	76	theme	composition	100:110	arg1	investigation					71:83	the investigation	67:83	the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease	67:189	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	6	77	from	acids	1370:1374	arg1	medium					1391:1396	the culture medium	1379:1396	the culture medium of healthy and the disease model cells	1379:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	4	78	theme	sample	933:938	arg1	preparation					940:950	sample preparation	933:950	sample preparation of culture medium	933:968	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	5	79	theme	amino	1313:1317	arg1	acids					1319:1323	amino acids	1313:1323	amino acids	1313:1323	The method proved to be sensitive, reliable and highly accurate for the quantitation of amino acids and lactic acid.					
35217259	1	80	from	study	404:408	arg1	cells					481:485	non-alcoholic fatty liver disease model cells	441:485	non-alcoholic fatty liver disease model cells	441:485	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	1	80	from	study	404:408	arg1	"					435:435	"healthy"	427:435	"healthy"	427:435	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	6	81	theme	altered	1455:1461	arg1	Ala					1478:1480	Ala	1478:1480	Ala	1478:1480	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	81	theme	altered	1455:1461	arg1	Gln					1488:1490	Gln	1488:1490	Gln	1488:1490	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	81	theme	altered	1455:1461	arg1	levels					1463:1468	altered levels	1455:1468	altered levels of Arg	1455:1475	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	81	theme	altered	1455:1461	arg1	acid					1503:1506	lactic acid	1496:1506	lactic acid	1496:1506	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	6	81	theme	altered	1455:1461	arg1	Glu					1483:1485	Glu	1483:1485	Glu	1483:1485	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	4	82	theme	culture	955:961	arg1	medium					963:968	culture medium	955:968	culture medium	955:968	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	6	83	theme	disease	1417:1423	arg1	model					1425:1429	the disease model	1413:1429	the disease model	1413:1429	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	1	84	theme	comparative	392:402	arg1	study					404:408	the comparative study	388:408	the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2	388:491	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	85	theme	linear	1016:1021	arg1	range					1031:1035	linear dynamic range	1016:1035	linear dynamic range	1016:1035	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	6	86	theme	health	1541:1546	arg1	control					1548:1554	health control	1541:1554	health control	1541:1554	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	0	87	theme	2-hydroxypropyl-β-cyclodextrin	22:51	arg1	additives					53:61	2-hydroxypropyl-β-cyclodextrin additives	22:61	2-hydroxypropyl-β-cyclodextrin additives	22:61	CE with Cu2+ ions and 2-hydroxypropyl-β-cyclodextrin additives for the investigation of amino acids composition of the culture medium in a cellular model of non-alcoholic fatty liver disease.					
35217259	1	88	theme	simultaneous	314:325	arg1	determination					327:339	the simultaneous determination	310:339	the simultaneous determination of amino acids and lactic acid	310:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	89	theme	CE	992:993	arg1	method					995:1000	the CE method	988:1000	the CE method	988:1000	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	6	90	theme	culture	1383:1389	arg1	medium					1391:1396	the culture medium	1379:1396	the culture medium of healthy and the disease model cells	1379:1435	The concentrations of amino acids in the culture medium of healthy and the disease model cells were measured and altered levels of Arg, Ala, Glu, Gln and lactic acid have been found in comparison to health control.					
35217259	1	91	theme	acids	350:354	arg1	determination					327:339	the simultaneous determination	310:339	the simultaneous determination of amino acids and lactic acid	310:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	5	92	theme	acid	1336:1339	arg1	quantitation					1297:1308	the quantitation	1293:1308	the quantitation of amino acids and lactic acid	1293:1339	The method proved to be sensitive, reliable and highly accurate for the quantitation of amino acids and lactic acid.					
35217259	2	93	with	cells	556:560	arg1	oleate					567:572	oleate	567:572	oleate	567:572	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	2	93	with	cells	556:560	arg1	palmitate					578:586	palmitate	578:586	palmitate	578:586	In vitro model of the disease was developed by exposure HepG2 cells with oleate and palmitate to simulate an excessive flow of fatty acids into hepatocytes.					
35217259	1	94	theme	2-hydroxypropyl-β-cyclodextrin	217:246	arg1	additives					248:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives	207:256	CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid	207:370	CE method with CuSO4 and 2-hydroxypropyl-β-cyclodextrin additives in sodium acetate background electrolyte pH 4.3 for the simultaneous determination of amino acids and lactic acid was adapted for the comparative study of metabolism in "healthy" and non-alcoholic fatty liver disease model cells HepG2.					
35217259	4	95	theme	areas	1087:1091	arg1	quantitation					1204:1215	quantitation	1204:1215	quantitation	1204:1215	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	95	theme	areas	1087:1091	arg1	repeatability					1038:1050	repeatability	1038:1050	repeatability	1038:1050	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	95	theme	areas	1087:1091	arg1	precision					1069:1077	intermediate precision	1056:1077	intermediate precision	1056:1077	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	95	theme	areas	1087:1091	arg1	accuracy					1114:1121	accuracy	1114:1121	accuracy (recovery rate and trueness estimated by reference method)	1114:1180	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	95	theme	areas	1087:1091	arg1	range					1031:1035	linear dynamic range	1016:1035	linear dynamic range	1016:1035	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
35217259	4	95	theme	areas	1087:1091	arg1	limits					1193:1198	detection limits	1183:1198	detection limits	1183:1198	In order to check whether the metabolism of amino acids changes in pathology, we proposed sample preparation of culture medium and characterized the CE method by evaluating linear dynamic range, repeatability and intermediate precision of peak areas and migration times, accuracy (recovery rate and trueness estimated by reference method), detection limits and quantitation limits.					
34499787	2	0	with	effect	357:362	arg1	activity					428:435	highly efficient drug-drug activity	401:435	highly efficient drug-drug activity	401:435	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	7	1	dep	@	1218:1218	arg1	GO					1219:1220	GO	1219:1220	GO	1219:1220	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	6	2	dep	5-FU	1094:1097	arg1	mL-1					1116:1119	54.1 and 103 μg mL-1	1100:1119	54.1 and 103 μg mL-1 on A549 and HepG-2	1100:1138	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	1	3	theme	biocompatible	229:241	arg1	nanocomposite					131:143	a nanocomposite	129:143	a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO)	129:224	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	3	theme	biocompatible	229:241	arg1	materials					243:251	biocompatible materials	229:251	biocompatible materials	229:251	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	7	4	theme	HPMC/5-FL	1209:1217	arg1	@					1218:1218	the HPMC/5-FL@GO	1205:1220	the HPMC/5-FL@GO	1205:1220	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	3	5	theme	X-ray	520:524	arg1	diffraction					526:536	X-ray diffraction	520:536	X-ray diffraction	520:536	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	6	theme	electron	548:555	arg1	microscopy					557:566	scanning electron microscopy	539:566	scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis	539:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	2	7	theme	drug	285:288	arg1	activity					290:297	the drug activity	281:297	the drug activity of immobilized 5-fluorouracil (5-FU)	281:334	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	3	8	theme	energy	581:586	arg1	microscopy					637:646	transmission electron microscopy	615:646	transmission electron microscopy	615:646	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	8	theme	energy	581:586	arg1	analysis					667:674	thermogravimetric analysis	649:674	thermogravimetric analysis	649:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	8	theme	energy	581:586	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	7	9	theme	biomedical	1237:1246	arg1	application					1248:1258	a biomedical application	1235:1258	a biomedical application such as cancer therapy with the unique biocompatible to human cells	1235:1326	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	4	10	theme	homogenous	754:763	arg1	structure					794:802	A homogenous and compatible nanocomposite structure	752:802	A homogenous and compatible nanocomposite structure with a homogenous drug distribution	752:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	6	11	from	mL-1	1045:1048	arg1	HepG-2					1062:1067	HepG-2	1062:1067	HepG-2	1062:1067	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	6	11	from	mL-1	1045:1048	arg1	A549					1053:1056	A549	1053:1056	A549	1053:1056	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	4	12	theme	nanocomposite	780:792	arg1	structure					794:802	A homogenous and compatible nanocomposite structure	752:802	A homogenous and compatible nanocomposite structure with a homogenous drug distribution	752:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	7	13	theme	human	1316:1320	arg1	cells					1322:1326	human cells	1316:1326	human cells	1316:1326	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	2	14	theme	treatment	376:384	arg1	protocols					386:394	long-run treatment protocols	367:394	long-run treatment protocols	367:394	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	3	15	theme	scanning	539:546	arg1	microscopy					557:566	scanning electron microscopy	539:566	scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis	539:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	1	16	theme	hydroxypropyl	165:177	arg1	methylcellulose					179:193	hydroxypropyl methylcellulose	165:193	hydroxypropyl methylcellulose (HPMC)	165:200	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	16	theme	hydroxypropyl	165:177	arg1	HPMC					196:199	HPMC	196:199	HPMC	196:199	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	7	17	theme	attained	1187:1194	arg1	results					1196:1202	the attained results	1183:1202	the attained results	1183:1202	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	6	18	theme	nanocomposite	1013:1025	arg1	activities					990:999	The antitumor activities	976:999	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2)	976:1068	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	6	18	theme	nanocomposite	1013:1025	arg1	lower					1075:1079	lower	1075:1079	lower	1075:1079	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	7	19	with	therapy	1275:1281	arg1	biocompatible					1299:1311	biocompatible	1299:1311	biocompatible	1299:1311	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	2	20	theme	immobilized	302:312	arg1	5-FU					330:333	5-FU	330:333	5-FU	330:333	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	2	20	theme	immobilized	302:312	arg1	5-fluorouracil					314:327	immobilized 5-fluorouracil	302:327	immobilized 5-fluorouracil (5-FU)	302:334	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	7	21	theme	cancer	1268:1273	arg1	therapy					1275:1281	cancer therapy	1268:1281	cancer therapy with the unique biocompatible to human cells	1268:1326	CONCLUSION AND IMPLICATIONS According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.					
34499787	5	22	theme	normal	933:938	arg1	lines					950:954	normal Vero cell lines	933:954	normal Vero cell lines	933:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	3	23	theme	dispersive	588:597	arg1	microscopy					637:646	transmission electron microscopy	615:646	transmission electron microscopy	615:646	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	23	theme	dispersive	588:597	arg1	analysis					667:674	thermogravimetric analysis	649:674	thermogravimetric analysis	649:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	23	theme	dispersive	588:597	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	4	24	theme	homogenous	811:820	arg1	distribution					827:838	a homogenous drug distribution	809:838	a homogenous drug distribution	809:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	5	25	theme	Vero	940:943	arg1	lines					950:954	normal Vero cell lines	933:954	normal Vero cell lines	933:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	5	26	theme	prepared	872:879	arg1	nanocomposite					881:893	the prepared nanocomposite	868:893	the prepared nanocomposite	868:893	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	4	27	theme	compatible	769:778	arg1	structure					794:802	A homogenous and compatible nanocomposite structure	752:802	A homogenous and compatible nanocomposite structure with a homogenous drug distribution	752:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	5	28	contain	has	895:897	arg2	effect					918:923	a low cytotoxicity effect	899:923	a low cytotoxicity effect against normal Vero cell lines	899:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	5	28	contain	has	895:897	arg1	nanocomposite					881:893	the prepared nanocomposite	868:893	the prepared nanocomposite	868:893	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	2	29	theme	efficient	408:416	arg1	activity					428:435	highly efficient drug-drug activity	401:435	highly efficient drug-drug activity	401:435	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	2	30	theme	drug-drug	418:426	arg1	activity					428:435	highly efficient drug-drug activity	401:435	highly efficient drug-drug activity	401:435	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	1	31	dep	@	155:155	arg1	GO					156:157	GO	156:157	GO	156:157	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	5	32	theme	cell	945:948	arg1	lines					950:954	normal Vero cell lines	933:954	normal Vero cell lines	933:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	1	33	theme	HPMC/5-FL	146:154	arg1	nanocomposite					131:143	a nanocomposite	129:143	a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO)	129:224	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	33	theme	HPMC/5-FL	146:154	arg1	@					155:155	HPMC/5-FL@GO	146:157	HPMC/5-FL@GO	146:157	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	0	34	theme	drug	58:61	arg1	system					71:76	drug carrier system	58:76	drug carrier system for 5-fluorouracil	58:95	Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5-fluorouracil.					
34499787	3	35	theme	ATR-FTIR	497:504	arg1	spectroscopy					506:517	ATR-FTIR spectroscopy	497:517	ATR-FTIR spectroscopy	497:517	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	36	theme	dynamic	681:687	arg1	scattering					695:704	dynamic light scattering	681:704	dynamic light scattering	681:704	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	5	37	theme	low	901:903	arg1	effect					918:923	a low cytotoxicity effect	899:923	a low cytotoxicity effect against normal Vero cell lines	899:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	6	38	theme	same	1008:1011	arg1	nanocomposite					1013:1025	the same nanocomposite	1004:1025	the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2)	1004:1068	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	1	39	dep	oxide	215:219	arg1	GO					222:223	GO	222:223	GO	222:223	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	3	40	theme	transmission	615:626	arg1	microscopy					637:646	transmission electron microscopy	615:646	transmission electron microscopy	615:646	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	40	theme	transmission	615:626	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	5	41	theme	cytotoxicity	905:916	arg1	effect					918:923	a low cytotoxicity effect	899:923	a low cytotoxicity effect against normal Vero cell lines	899:954	Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU.					
34499787	1	42	theme	graphene	206:213	arg1	oxide					215:219	graphene oxide	206:219	graphene oxide (GO)	206:224	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	4	43	with	structure	794:802	arg1	distribution					827:838	a homogenous drug distribution	809:838	a homogenous drug distribution	809:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	3	44	theme	X-ray	599:603	arg1	microscopy					637:646	transmission electron microscopy	615:646	transmission electron microscopy	615:646	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	44	theme	X-ray	599:603	arg1	analysis					667:674	thermogravimetric analysis	649:674	thermogravimetric analysis	649:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	44	theme	X-ray	599:603	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	0	45	theme	carrier	63:69	arg1	system					71:76	drug carrier system	58:76	drug carrier system for 5-fluorouracil	58:95	Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5-fluorouracil.					
34499787	6	46	theme	antitumor	980:988	arg1	activities					990:999	The antitumor activities	976:999	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2)	976:1068	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	6	46	theme	antitumor	980:988	arg1	lower					1075:1079	lower	1075:1079	lower	1075:1079	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	3	47	dep	METHOD	438:443	arg1	characterized					480:492	characterized	480:492	were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study	475:749	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	1	48	dep	AIM	98:100	arg1	aims					113:116	aims	113:116	aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials	113:251	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	49	from	oxide	215:219	arg1	nanocomposite					131:143	a nanocomposite	129:143	a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO)	129:224	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	49	from	oxide	215:219	arg1	@					155:155	HPMC/5-FL@GO	146:157	HPMC/5-FL@GO	146:157	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	49	from	oxide	215:219	arg1	materials					243:251	biocompatible materials	229:251	biocompatible materials	229:251	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	6	50	dep	nanocomposite	1013:1025	arg1	mL-1					1045:1048	20.4 and 74.3 μg mL-1	1028:1048	20.4 and 74.3 μg mL-1 on A549 and HepG-2	1028:1067	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	4	51	theme	drug	822:825	arg1	distribution					827:838	a homogenous drug distribution	809:838	a homogenous drug distribution	809:838	A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.					
34499787	3	52	theme	light	689:693	arg1	scattering					695:704	dynamic light scattering	681:704	dynamic light scattering	681:704	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	53	theme	thermogravimetric	649:665	arg1	analysis					667:674	thermogravimetric analysis	649:674	thermogravimetric analysis	649:674	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	53	theme	thermogravimetric	649:665	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	1	54	from	methylcellulose	179:193	arg1	nanocomposite					131:143	a nanocomposite	129:143	a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO)	129:224	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	54	from	methylcellulose	179:193	arg1	@					155:155	HPMC/5-FL@GO	146:157	HPMC/5-FL@GO	146:157	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	1	54	from	methylcellulose	179:193	arg1	materials					243:251	biocompatible materials	229:251	biocompatible materials	229:251	AIM This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.					
34499787	2	55	theme	5-fluorouracil	314:327	arg1	activity					290:297	the drug activity	281:297	the drug activity of immobilized 5-fluorouracil (5-FU)	281:334	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	2	56	theme	protocols	386:394	arg1	effect					357:362	the side effect	348:362	the side effect of long-run treatment protocols with highly efficient drug-drug activity	348:435	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	3	57	theme	electron	628:635	arg1	microscopy					637:646	transmission electron microscopy	615:646	transmission electron microscopy	615:646	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	57	theme	electron	628:635	arg1	analysis					605:612	energy dispersive X-ray analysis	581:612	energy dispersive X-ray analysis	581:612	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	3	58	theme	Different	457:465	arg1	samples					467:473	Different samples	457:473	Different samples	457:473	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	2	59	theme	side	352:355	arg1	effect					357:362	the side effect	348:362	the side effect of long-run treatment protocols with highly efficient drug-drug activity	348:435	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	2	60	theme	long-run	367:374	arg1	protocols					386:394	long-run treatment protocols	367:394	long-run treatment protocols	367:394	The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drug-drug activity.					
34499787	6	61	from	mL-1	1116:1119	arg1	HepG-2					1133:1138	HepG-2	1133:1138	HepG-2	1133:1138	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	6	61	from	mL-1	1116:1119	arg1	A549					1124:1127	A549	1124:1127	A549	1124:1127	The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL-1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL-1 on A549 and HepG-2).					
34499787	3	62	theme	anticancer	734:743	arg1	study					745:749	anticancer study	734:749	anticancer study	734:749	METHOD AND RESULTS Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study.					
34499787	0	63	theme	oxide	39:43	arg1	composite					45:53	oxide composite	39:53	oxide composite	39:53	Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5-fluorouracil.					
35698997	8	0	theme	healing	1164:1170	arg1	stages					1148:1153	the early stages	1138:1153	the early stages of wound healing	1138:1170	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	0	1	with	scaffold	39:46	arg1	methylene					53:61	methylene blue	53:66	methylene blue	53:66	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	1	2	theme	common	171:176	arg1	causes					178:183	the most common causes	162:183	the most common causes of trauma-related death	162:207	Uncontrollable bleeding and infection are two of the most common causes of trauma-related death.					
35698997	4	3	theme	common	646:651	arg1	materials					664:672	common hemostatic materials	646:672	common hemostatic materials	646:672	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	0	4	theme	photodynamic	91:102	arg1	therapy					104:110	antimicrobial photodynamic therapy	77:110	antimicrobial photodynamic therapy	77:110	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	8	5	theme	wound	1158:1162	arg1	healing					1164:1170	wound healing	1158:1170	wound healing	1158:1170	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	8	6	theme	wound	1121:1125	arg1	exudate					1127:1133	wound exudate	1121:1133	wound exudate	1121:1133	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	1	7	theme	causes	178:183	arg1	two					155:157	two	155:157	two	155:157	Uncontrollable bleeding and infection are two of the most common causes of trauma-related death.					
35698997	1	7	theme	causes	178:183	arg1	causes					178:183	the most common causes	162:183	the most common causes of trauma-related death	162:207	Uncontrollable bleeding and infection are two of the most common causes of trauma-related death.					
35698997	3	8	theme	platelet	399:406	arg1	binding					408:414	platelet binding	399:414	platelet binding	399:414	Keratin-based biomaterials have been reported to exhibit the functions of enhancing platelet binding and activating and facilitating fibrinogen polymerization.					
35698997	4	9	theme	hemostatic	570:579	arg1	ability					581:587	hemostatic ability	570:587	hemostatic ability	570:587	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	5	10	theme	freeze-gelation	755:769	arg1	method					771:776	the freeze-gelation method	751:776	the freeze-gelation method	751:776	Methylene blue-loaded keratin/alginate composite scaffolds were prepared by the freeze-gelation method.					
35698997	5	11	theme	Methylene	675:683	arg1	scaffolds					724:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds were prepared by the freeze-gelation method.					
35698997	6	12	theme	liquid	824:829	arg1	absorption					831:840	1600% liquid absorption	818:840	1600% liquid absorption	818:840	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	4	13	theme	materials	664:672	arg1	shortcomings					630:641	the shortcomings	626:641	the shortcomings of common hemostatic materials	626:672	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	8	14	theme	burst	1094:1098	arg1	release					1100:1106	high burst release	1089:1106	high burst release	1089:1106	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	4	15	theme	good	529:532	arg1	biodegradability					534:549	good biodegradability	529:549	good biodegradability	529:549	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	9	16	theme	photodynamic	1278:1289	arg1	effect					1291:1296	an antimicrobial photodynamic effect	1261:1296	an antimicrobial photodynamic effect	1261:1296	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	5	17	theme	blue-loaded	685:695	arg1	scaffolds					724:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds were prepared by the freeze-gelation method.					
35698997	6	18	theme	%	822:822	arg1	absorption					831:840	1600% liquid absorption	818:840	1600% liquid absorption	818:840	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	4	19	theme	hemostatic	653:662	arg1	materials					664:672	common hemostatic materials	646:672	common hemostatic materials	646:672	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	9	20	theme	antimicrobial	1201:1213	arg1	assay					1233:1237	the antimicrobial photoinactivation assay	1197:1237	the antimicrobial photoinactivation assay	1197:1237	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	5	21	theme	composite	714:722	arg1	scaffolds					724:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds were prepared by the freeze-gelation method.					
35698997	5	22	theme	keratin/alginate	697:712	arg1	scaffolds					724:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds	675:732	Methylene blue-loaded keratin/alginate composite scaffolds were prepared by the freeze-gelation method.					
35698997	6	23	theme	1600	818:821	arg1	%					822:822	%	822:822	%	822:822	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	4	24	with	material	515:522	arg1	biodegradability					534:549	good biodegradability	529:549	good biodegradability	529:549	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	4	24	with	material	515:522	arg1	function					608:615	antibacterial function	594:615	antibacterial function	594:615	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	4	24	with	material	515:522	arg1	biocompatibility					552:567	biocompatibility	552:567	biocompatibility	552:567	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	4	24	with	material	515:522	arg1	ability					581:587	hemostatic ability	570:587	hemostatic ability	570:587	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	8	25	theme	early	1142:1146	arg1	stages					1148:1153	the early stages	1138:1153	the early stages of wound healing	1138:1170	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	7	26	theme	synergistic	970:980	arg1	action					982:987	the keratin/alginate composite scaffolds' synergistic action	928:987	the keratin/alginate composite scaffolds' synergistic action	928:987	We find that the keratin/alginate composite scaffolds' synergistic action may significantly reduce hemostasis time.					
35698997	1	27	theme	trauma-related	188:201	arg1	death					203:207	trauma-related death	188:207	trauma-related death	188:207	Uncontrollable bleeding and infection are two of the most common causes of trauma-related death.					
35698997	0	28	theme	hemostatic	2:11	arg1	scaffold					39:46	A hemostatic keratin/alginate hydrogel scaffold	0:46	A hemostatic keratin/alginate hydrogel scaffold with methylene blue	0:66	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	9	29	theme	colonies	1356:1363	arg1	growth					1346:1351	the fast growth	1337:1351	the fast growth of colonies	1337:1363	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	1	30	theme	death	203:207	arg1	causes					178:183	the most common causes	162:183	the most common causes of trauma-related death	162:207	Uncontrollable bleeding and infection are two of the most common causes of trauma-related death.					
35698997	0	31	theme	hydrogel	30:37	arg1	scaffold					39:46	A hemostatic keratin/alginate hydrogel scaffold	0:46	A hemostatic keratin/alginate hydrogel scaffold with methylene blue	0:66	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	2	32	with	materials	231:239	arg1	effectiveness					280:292	high hemostatic and antibacterial effectiveness	246:292	high hemostatic and antibacterial effectiveness	246:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	6	33	theme	composite	783:791	arg1	scaffolds					793:801	The composite scaffolds	779:801	The composite scaffolds	779:801	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	0	34	theme	keratin/alginate	13:28	arg1	scaffold					39:46	A hemostatic keratin/alginate hydrogel scaffold	0:46	A hemostatic keratin/alginate hydrogel scaffold with methylene blue	0:66	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	3	35	theme	Keratin-based	315:327	arg1	biomaterials					329:340	Keratin-based biomaterials	315:340	Keratin-based biomaterials	315:340	Keratin-based biomaterials have been reported to exhibit the functions of enhancing platelet binding and activating and facilitating fibrinogen polymerization.					
35698997	7	36	theme	keratin/alginate	932:947	arg1	action					982:987	the keratin/alginate composite scaffolds' synergistic action	928:987	the keratin/alginate composite scaffolds' synergistic action	928:987	We find that the keratin/alginate composite scaffolds' synergistic action may significantly reduce hemostasis time.					
35698997	9	37	theme	photoinactivation	1215:1231	arg1	assay					1233:1237	the antimicrobial photoinactivation assay	1197:1237	the antimicrobial photoinactivation assay	1197:1237	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	2	38	theme	hemostatic	251:260	arg1	effectiveness					280:292	high hemostatic and antibacterial effectiveness	246:292	high hemostatic and antibacterial effectiveness	246:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	7	39	theme	composite	949:957	arg1	action					982:987	the keratin/alginate composite scaffolds' synergistic action	928:987	the keratin/alginate composite scaffolds' synergistic action	928:987	We find that the keratin/alginate composite scaffolds' synergistic action may significantly reduce hemostasis time.					
35698997	2	40	theme	high	246:249	arg1	effectiveness					280:292	high hemostatic and antibacterial effectiveness	246:292	high hemostatic and antibacterial effectiveness	246:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	8	41	theme	drug-loaded	1057:1067	arg1	scaffolds					1069:1077	the drug-loaded scaffolds	1053:1077	the drug-loaded scaffolds	1053:1077	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	3	42	theme	fibrinogen	448:457	arg1	polymerization					459:472	fibrinogen polymerization	448:472	fibrinogen polymerization	448:472	Keratin-based biomaterials have been reported to exhibit the functions of enhancing platelet binding and activating and facilitating fibrinogen polymerization.					
35698997	9	43	theme	fast	1341:1344	arg1	growth					1346:1351	the fast growth	1337:1351	the fast growth of colonies	1337:1363	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	4	44	theme	hemostatic	504:513	arg1	material					515:522	a hemostatic material	502:522	a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function	502:615	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	6	45	theme	good	870:873	arg1	biocompatibility					875:890	good biocompatibility	870:890	good biocompatibility	870:890	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	2	46	theme	safe	226:229	arg1	materials					231:239	safe materials	226:239	developing safe materials with high hemostatic and antibacterial effectiveness	215:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	4	47	theme	antibacterial	594:606	arg1	function					608:615	antibacterial function	594:615	antibacterial function	594:615	In this study, we designed a hemostatic material with good biodegradability, biocompatibility, hemostatic ability, and antibacterial function to solve the shortcomings of common hemostatic materials.					
35698997	2	48	theme	developing	215:224	arg1	materials					231:239	safe materials	226:239	developing safe materials with high hemostatic and antibacterial effectiveness	215:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	9	49	theme	antimicrobial	1264:1276	arg1	effect					1291:1296	an antimicrobial photodynamic effect	1261:1296	an antimicrobial photodynamic effect	1261:1296	The results obtained by the antimicrobial photoinactivation assay in vitro suggest that an antimicrobial photodynamic effect might be triggered, thereby preventing the fast growth of colonies.					
35698997	6	50	theme	well-interconnected	843:861	arg1	pores					863:867	well-interconnected pores	843:867	well-interconnected pores	843:867	The composite scaffolds exhibited over 1600% liquid absorption, well-interconnected pores, good biocompatibility, and biodegradability.					
35698997	0	51	theme	antimicrobial	77:89	arg1	therapy					104:110	antimicrobial photodynamic therapy	77:110	antimicrobial photodynamic therapy	77:110	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35698997	7	52	theme	hemostasis	1014:1023	arg1	time					1025:1028	hemostasis time	1014:1028	hemostasis time	1014:1028	We find that the keratin/alginate composite scaffolds' synergistic action may significantly reduce hemostasis time.					
35698997	2	53	theme	antibacterial	266:278	arg1	effectiveness					280:292	high hemostatic and antibacterial effectiveness	246:292	high hemostatic and antibacterial effectiveness	246:292	Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge.					
35698997	8	54	theme	high	1089:1092	arg1	release					1100:1106	high burst release	1089:1106	high burst release	1089:1106	To prevent infection, the drug-loaded scaffolds generated high burst release by absorbing wound exudate in the early stages of wound healing.					
35698997	0	55	theme	blue	63:66	arg1	methylene					53:61	methylene blue	53:66	methylene blue	53:66	A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy.					
35880575	5	0	theme	fluorescence	726:737	arg1	microscopy					739:748	fluorescence microscopy	726:748	fluorescence microscopy	726:748	According to optical and fluorescence microscopy, the microcapsules displayed a spherical morphology, and their synthesis is dependent on the concentration of Dex-OA nanoconjugates.					
35880575	5	1	theme	spherical	781:789	arg1	morphology					791:800	a spherical morphology	779:800	a spherical morphology	779:800	According to optical and fluorescence microscopy, the microcapsules displayed a spherical morphology, and their synthesis is dependent on the concentration of Dex-OA nanoconjugates.					
35880575	7	2	theme	robust	1004:1009	arg1	method					1025:1030	a robust and efficient method	1002:1030	a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1002:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	2	3	theme	amide-linkage	424:436	arg1	chemistry					438:446	facile amide-linkage chemistry	417:446	facile amide-linkage chemistry	417:446	Herein, nanoconjugates based on dextran and oleic acid (Dex-OA) were synthesized via facile amide-linkage chemistry.					
35880575	7	4	theme	natural	1081:1087	arg1	blocks					1110:1115	fully natural amphiphilic building blocks	1075:1115	fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1075:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	5	theme	nanosized	205:213	arg1	structures					215:224	micro- and nanosized structures	194:224	micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	194:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	7	6	theme	amphiphilic	1089:1099	arg1	blocks					1110:1115	fully natural amphiphilic building blocks	1075:1115	fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1075:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	7	theme	intrinsic	295:303	arg1	properties					320:329	their intrinsic and functional properties	289:329	their intrinsic and functional properties	289:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	8	theme	structures	215:224	arg1	construction					178:189	the construction	174:189	the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	174:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	9	theme	Saccharide/lipid	107:122	arg1	blocks					163:168	attractive building blocks	143:168	attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	143:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	9	theme	Saccharide/lipid	107:122	arg1	nanoconjugates					124:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	2	10	theme	facile	417:422	arg1	chemistry					438:446	facile amide-linkage chemistry	417:446	facile amide-linkage chemistry	417:446	Herein, nanoconjugates based on dextran and oleic acid (Dex-OA) were synthesized via facile amide-linkage chemistry.					
35880575	5	11	theme	Dex-OA	860:865	arg1	nanoconjugates					867:880	Dex-OA nanoconjugates	860:880	Dex-OA nanoconjugates	860:880	According to optical and fluorescence microscopy, the microcapsules displayed a spherical morphology, and their synthesis is dependent on the concentration of Dex-OA nanoconjugates.					
35880575	7	12	theme	microcapsules	1056:1068	arg1	construction					1040:1051	the construction	1036:1051	the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1036:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	13	from	construction	1040:1051	arg1	blocks					1110:1115	fully natural amphiphilic building blocks	1075:1115	fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1075:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	3	14	theme	Dex-OA	463:468	arg1	micelles					470:477	The resultant Dex-OA micelles	449:477	The resultant Dex-OA micelles	449:477	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	1	15	theme	functional	309:318	arg1	properties					320:329	their intrinsic and functional properties	289:329	their intrinsic and functional properties	289:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	0	16	theme	Alternative	39:49	arg1	Blocks					60:65	Alternative Building Blocks	39:65	Alternative Building Blocks for Highly Biocompatible Microcapsules	39:104	Polysaccharide/Lipid Nanoconjugates as Alternative Building Blocks for Highly Biocompatible Microcapsules.					
35880575	1	17	theme	properties	320:329	arg1	courtesy					277:284	courtesy	277:284	courtesy of their intrinsic and functional properties	277:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	17	theme	properties	320:329	arg1	roles					241:245	the roles	237:245	the roles of glycolipids in human body	237:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	7	18	theme	protocell	1191:1199	arg1	research					1201:1208	protocell research	1191:1208	protocell research	1191:1208	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	19	theme	attractive	143:152	arg1	blocks					163:168	attractive building blocks	143:168	attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	143:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	19	theme	attractive	143:152	arg1	nanoconjugates					124:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	3	20	theme	water-filled	514:525	arg1	microcapsules					527:539	spherical water-filled microcapsules	504:539	spherical water-filled microcapsules	504:539	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	4	21	theme	aqueous	644:650	arg1	media					652:656	aqueous media	644:656	aqueous media	644:656	By cross-linking, the microcapsules could be transferred to aqueous media, forming a stable microcapsule dispersion.					
35880575	4	22	theme	microcapsule	676:687	arg1	dispersion					689:698	a stable microcapsule dispersion	667:698	a stable microcapsule dispersion	667:698	By cross-linking, the microcapsules could be transferred to aqueous media, forming a stable microcapsule dispersion.					
35880575	1	23	theme	building	154:161	arg1	blocks					163:168	attractive building blocks	143:168	attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	143:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	23	theme	building	154:161	arg1	nanoconjugates					124:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates	107:137	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	5	24	theme	nanoconjugates	867:880	arg1	concentration					843:855	the concentration	839:855	the concentration of Dex-OA nanoconjugates	839:880	According to optical and fluorescence microscopy, the microcapsules displayed a spherical morphology, and their synthesis is dependent on the concentration of Dex-OA nanoconjugates.					
35880575	3	25	theme	emulsification	560:573	arg1	process					575:581	a water-in-oil emulsification process	545:581	a water-in-oil emulsification process	545:581	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	7	26	from	application	1140:1150	arg1	microreactors					1215:1227	microreactors	1215:1227	microreactors	1215:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	26	from	application	1140:1150	arg1	fields					1163:1168	diverse fields	1155:1168	diverse fields such as biomedicine, protocell research, and microreactors	1155:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	26	from	application	1140:1150	arg1	biomedicine					1178:1188	biomedicine	1178:1188	biomedicine	1178:1188	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	26	from	application	1140:1150	arg1	research					1201:1208	protocell research	1191:1208	protocell research	1191:1208	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	27	theme	glycolipids	250:260	arg1	courtesy					277:284	courtesy	277:284	courtesy of their intrinsic and functional properties	277:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	27	theme	glycolipids	250:260	arg1	roles					241:245	the roles	237:245	the roles of glycolipids in human body	237:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	0	28	theme	Building	51:58	arg1	Blocks					60:65	Alternative Building Blocks	39:65	Alternative Building Blocks for Highly Biocompatible Microcapsules	39:104	Polysaccharide/Lipid Nanoconjugates as Alternative Building Blocks for Highly Biocompatible Microcapsules.					
35880575	3	29	theme	resultant	453:461	arg1	micelles					470:477	The resultant Dex-OA micelles	449:477	The resultant Dex-OA micelles	449:477	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	1	30	from	glycolipids	250:260	arg1	body					271:274	human body	265:274	human body	265:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	3	31	theme	spherical	504:512	arg1	microcapsules					527:539	spherical water-filled microcapsules	504:539	spherical water-filled microcapsules	504:539	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	6	32	theme	labeled	964:970	arg1	dextran					972:978	fluorescently labeled dextran	950:978	fluorescently labeled dextran	950:978	Furthermore, the microcapsules could easily encapsulate and retain fluorescently labeled dextran.					
35880575	3	33	theme	water-in-oil	547:558	arg1	process					575:581	a water-in-oil emulsification process	545:581	a water-in-oil emulsification process	545:581	The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process.					
35880575	7	34	from	blocks	1110:1115	arg1	microcapsules					1056:1068	microcapsules	1056:1068	microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1056:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	34	from	blocks	1110:1115	arg1	construction					1040:1051	the construction	1036:1051	the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1036:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	35	from	roles	241:245	arg1	body					271:274	human body	265:274	human body	265:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	2	36	theme	oleic	376:380	arg1	Dex-OA					388:393	Dex-OA	388:393	Dex-OA	388:393	Herein, nanoconjugates based on dextran and oleic acid (Dex-OA) were synthesized via facile amide-linkage chemistry.					
35880575	2	36	theme	oleic	376:380	arg1	acid					382:385	oleic acid	376:385	oleic acid (Dex-OA)	376:394	Herein, nanoconjugates based on dextran and oleic acid (Dex-OA) were synthesized via facile amide-linkage chemistry.					
35880575	7	37	theme	diverse	1155:1161	arg1	microreactors					1215:1227	microreactors	1215:1227	microreactors	1215:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	37	theme	diverse	1155:1161	arg1	fields					1163:1168	diverse fields	1155:1168	diverse fields such as biomedicine, protocell research, and microreactors	1155:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	37	theme	diverse	1155:1161	arg1	biomedicine					1178:1188	biomedicine	1178:1188	biomedicine	1178:1188	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	37	theme	diverse	1155:1161	arg1	research					1201:1208	protocell research	1191:1208	protocell research	1191:1208	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	7	38	with	blocks	1110:1115	arg1	potential					1126:1134	the potential	1122:1134	the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1122:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	39	theme	human	265:269	arg1	body					271:274	human body	265:274	human body	265:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	40	from	body	271:274	arg1	courtesy					277:284	courtesy	277:284	courtesy of their intrinsic and functional properties	277:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	1	40	from	body	271:274	arg1	roles					241:245	the roles	237:245	the roles of glycolipids in human body	237:274	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35880575	4	41	theme	stable	669:674	arg1	dispersion					689:698	a stable microcapsule dispersion	667:698	a stable microcapsule dispersion	667:698	By cross-linking, the microcapsules could be transferred to aqueous media, forming a stable microcapsule dispersion.					
35880575	7	42	theme	efficient	1015:1023	arg1	method					1025:1030	a robust and efficient method	1002:1030	a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1002:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	0	43	theme	Biocompatible	78:90	arg1	Microcapsules					92:104	Highly Biocompatible Microcapsules	71:104	Highly Biocompatible Microcapsules	71:104	Polysaccharide/Lipid Nanoconjugates as Alternative Building Blocks for Highly Biocompatible Microcapsules.					
35880575	7	44	theme	building	1101:1108	arg1	blocks					1110:1115	fully natural amphiphilic building blocks	1075:1115	fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors	1075:1227	This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors.					
35880575	1	45	theme	micro-	194:199	arg1	structures					215:224	micro- and nanosized structures	194:224	micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties	194:329	Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties.					
35597379	4	0	theme	of	778:779	arg1	sugars					789:794	lower of neutral sugars	772:794	lower of neutral sugars	772:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	7	1	with	pectins	1124:1130	arg1	samples					1166:1172	slightly upper technological samples	1137:1172	slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1137:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	4	2	theme	sugars	789:794	arg1	content					739:745	higher content	732:745	higher content of galacturonic acid and lower of neutral sugars	732:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	3	theme	glucose	1484:1490	arg1	capacity					1503:1510	higher glucose adsorption capacity	1477:1510	higher glucose adsorption capacity (4 mmol g-1 at 200 min)	1477:1534	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	3	4	theme	yield	526:530	arg1	value					532:536	The experimental yield value	509:536	The experimental yield value (6.7%)	509:543	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	4	theme	yield	526:530	arg1	%					542:542	6.7%	539:542	6.7%	539:542	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	5	dep	conditions	607:616	arg1	pH 1.5					634:639	pH 1.5	634:639	pH 1.5	634:639	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	5	dep	conditions	607:616	arg1	90 min					626:631	90 min	626:631	90 min	626:631	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	5	dep	conditions	607:616	arg1	60 °C					619:623	60 °C	619:623	60 °C	619:623	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	4	6	theme	galacturonic	750:761	arg1	acid					763:766	galacturonic acid	750:766	galacturonic acid	750:766	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	7	theme	α-amylase	1548:1556	arg1	inhibition					1558:1567	α-amylase inhibition	1548:1567	α-amylase inhibition (73.7%)	1548:1575	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	8	7	theme	α-amylase	1548:1556	arg1	%					1574:1574	73.7%	1570:1574	73.7%	1570:1574	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	6	8	theme	spectral	1037:1044	arg1	analysis					1046:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	7	9	theme	emulsifying	1254:1264	arg1	38.5 m2/g					1276:1284	38.5 m2/g	1276:1284	38.5 m2/g	1276:1284	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	7	9	theme	emulsifying	1254:1264	arg1	activity					1266:1273	emulsifying activity	1254:1273	emulsifying activity (38.5 m2/g)	1254:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	0	10	theme	Physicochemical	102:116	arg1	properties					167:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	5	11	theme	higher	938:943	arg1	extent					945:950	a higher extent	936:950	a higher extent than ultrasound treatment (800 kDa)	936:986	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	4	12	theme	CAE	826:828	arg1	pectin					830:835	CAE pectin	826:835	CAE pectin	826:835	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	13	theme	date	1298:1301	arg1	pectins					1303:1309	date pectins	1298:1309	date pectins obtained by UAE	1298:1325	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	0	14	theme	techno-functional	119:135	arg1	properties					167:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	1	15	theme	date	211:214	arg1	fruits					216:221	date fruits	211:221	date fruits	211:221	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
35597379	4	16	theme	UAE	799:801	arg1	pectin					803:808	UAE pectin	799:808	UAE pectin	799:808	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	17	from	150 min	1650:1656	arg1	1.4 mmol mM g-1					1631:1645	1.4 mmol mM g-1	1631:1645	1.4 mmol mM g-1	1631:1645	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	0	18	theme	antioxidant	138:148	arg1	properties					167:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	8	19	theme	potential	1759:1767	arg1	properties					1786:1795	potential health-promoting properties	1759:1795	potential health-promoting properties	1759:1795	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	2	20	theme	acid	486:489	arg1	CAE					503:505	CAE	503:505	CAE	503:505	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	20	theme	acid	486:489	arg1	extraction					491:500	conventional acid extraction	473:500	conventional acid extraction (CAE)	473:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	8	21	theme	enhanced	1337:1344	arg1	activity					1358:1365	enhanced antioxidant activity	1337:1365	enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively)	1337:1428	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	0	22	theme	antidiabetic	154:165	arg1	properties					167:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	Physicochemical, techno-functional, antioxidant and antidiabetic properties	102:176	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	0	23	theme	ultrasound	72:81	arg1	extraction					90:99	ultrasound pectin extraction	72:99	ultrasound pectin extraction	72:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	8	24	dep	activity	1358:1365	arg1	DW					1387:1388	24.3 and 61.0 mg/g DW	1368:1388	24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively	1368:1427	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	2	25	theme	process	360:366	arg1	methodology					327:337	Response surface methodology	310:337	Response surface methodology (RSM)	310:343	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	25	theme	process	360:366	arg1	tool					381:384	process optimization tool	360:384	process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE)	360:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	0	26	theme	New	0:2	arg1	approach					17:24	New valorization approach	0:24	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction	0:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	7	27	theme	holding	1200:1206	arg1	capacity					1208:1215	oil holding capacity	1196:1215	oil holding capacity	1196:1215	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	8	28	from	200 min	1527:1533	arg1	4 mmol g-1					1513:1522	4 mmol g-1	1513:1522	4 mmol g-1	1513:1522	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	2	29	theme	highest	401:407	arg1	yield					409:413	the highest yield	397:413	the highest yield using ultrasound-assisted extraction (UAE)	397:456	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	1	30	theme	common	272:277	arg1	variety					279:285	an Algerian common variety	260:285	an Algerian common variety	260:285	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
35597379	0	31	theme	Algerian	29:36	arg1	dates					38:42	Algerian dates	29:42	Algerian dates (Phoenix dactylifera L.)	29:67	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	0	31	theme	Algerian	29:36	arg1	Phoenix					45:51	Phoenix	45:51	Phoenix	45:51	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	5	32	theme	extracted	905:913	arg1	539 kDa					924:930	539 kDa	924:930	539 kDa	924:930	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	5	32	theme	extracted	905:913	arg1	pectins					915:921	the extracted pectins	901:921	the extracted pectins (539 kDa)	901:931	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	2	33	theme	conventional	473:484	arg1	CAE					503:505	CAE	503:505	CAE	503:505	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	33	theme	conventional	473:484	arg1	extraction					491:500	conventional acid extraction	473:500	conventional acid extraction (CAE)	473:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	6	34	theme	Infrared	1007:1014	arg1	FT-IR					1030:1034	FT-IR	1030:1034	FT-IR	1030:1034	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	6	34	theme	Infrared	1007:1014	arg1	Spectroscopy					1016:1027	Fourier-Transform Infrared Spectroscopy	989:1027	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	8	35	dep	diffusion	1620:1628	arg1	1.4 mmol mM g-1					1631:1645	1.4 mmol mM g-1	1631:1645	1.4 mmol mM g-1	1631:1645	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	2	36	theme	surface	319:325	arg1	methodology					327:337	Response surface methodology	310:337	Response surface methodology (RSM)	310:343	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	36	theme	surface	319:325	arg1	tool					381:384	process optimization tool	360:384	process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE)	360:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	36	theme	surface	319:325	arg1	RSM					340:342	RSM	340:342	RSM	340:342	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	8	37	theme	adsorption	1492:1501	arg1	capacity					1503:1510	higher glucose adsorption capacity	1477:1510	higher glucose adsorption capacity (4 mmol g-1 at 200 min)	1477:1534	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	1	38	theme	fruits	216:221	arg1	fortune					200:206	the great fortune	190:206	the great fortune of date fruits	190:221	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
35597379	7	39	theme	technological	1152:1164	arg1	samples					1166:1172	slightly upper technological samples	1137:1172	slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1137:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	8	40	from	150 min	1739:1745	arg1	0.1 mmol mM g-1					1720:1734	0.1 mmol mM g-1	1720:1734	0.1 mmol mM g-1	1720:1734	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	4	41	theme	monomeric	703:711	arg1	composition					713:723	the monomeric composition	699:723	the monomeric composition	699:723	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	42	theme	antidiabetic	1444:1455	arg1	properties					1457:1466	antidiabetic properties	1444:1466	antidiabetic properties	1444:1466	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	4	43	theme	lower	772:776	arg1	sugars					789:794	lower of neutral sugars	772:794	lower of neutral sugars	772:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	3	44	theme	experimental	513:524	arg1	value					532:536	The experimental yield value	509:536	The experimental yield value (6.7%)	509:543	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	44	theme	experimental	513:524	arg1	%					542:542	6.7%	539:542	6.7%	539:542	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	4	45	theme	neutral	781:787	arg1	sugars					789:794	lower of neutral sugars	772:794	lower of neutral sugars	772:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	8	46	theme	higher	1477:1482	arg1	capacity					1503:1510	higher glucose adsorption capacity	1477:1510	higher glucose adsorption capacity (4 mmol g-1 at 200 min)	1477:1534	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	8	47	theme	starch	1702:1707	arg1	digestion					1709:1717	starch digestion	1702:1717	starch digestion (0.1 mmol mM g-1 at 150 min)	1702:1746	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	4	48	theme	acid	763:766	arg1	content					739:745	higher content	732:745	higher content of galacturonic acid and lower of neutral sugars	732:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	7	49	from	samples	1166:1172	arg1	terms					1177:1181	terms	1177:1181	terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1177:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	1	50	theme	great	194:198	arg1	fortune					200:206	the great fortune	190:206	the great fortune of date fruits	190:221	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
35597379	7	51	theme	activity	1266:1273	arg1	terms					1177:1181	terms	1177:1181	terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1177:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	5	52	theme	ultrasound	957:966	arg1	800 kDa					979:985	800 kDa	979:985	800 kDa	979:985	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	5	52	theme	ultrasound	957:966	arg1	treatment					968:976	ultrasound treatment	957:976	ultrasound treatment (800 kDa)	957:986	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	0	53	dep	properties	167:176	arg1	approach					17:24	New valorization approach	0:24	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction	0:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	3	54	theme	model	674:678	arg1	validity					658:665	the validity	654:665	the validity of the model	654:678	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	8	55	theme	health-promoting	1769:1784	arg1	properties					1786:1795	potential health-promoting properties	1759:1795	potential health-promoting properties	1759:1795	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	3	56	theme	predicted	571:579	arg1	%					589:589	6.6%	586:589	6.6%	586:589	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	3	56	theme	predicted	571:579	arg1	one					581:583	the predicted one	567:583	the predicted one (6.6%)	567:590	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	8	57	theme	potential	1581:1589	arg1	capacity					1591:1598	potential capacity	1581:1598	potential capacity	1581:1598	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	8	58	theme	antioxidant	1346:1356	arg1	activity					1358:1365	enhanced antioxidant activity	1337:1365	enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively)	1337:1428	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	6	59	theme	low-methoxyl	1085:1096	arg1	pectins					1098:1104	low-methoxyl pectins	1085:1104	low-methoxyl pectins	1085:1104	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	7	60	theme	upper	1146:1150	arg1	samples					1166:1172	slightly upper technological samples	1137:1172	slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1137:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	8	61	dep	digestion	1709:1717	arg1	0.1 mmol mM g-1					1720:1734	0.1 mmol mM g-1	1720:1734	0.1 mmol mM g-1	1720:1734	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	8	62	dep	capacity	1503:1510	arg1	4 mmol g-1					1513:1522	4 mmol g-1	1513:1522	4 mmol g-1	1513:1522	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	8	63	theme	glucose	1612:1618	arg1	diffusion					1620:1628	glucose diffusion	1612:1628	glucose diffusion (1.4 mmol mM g-1 at 150 min)	1612:1657	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	0	64	theme	pectin	83:88	arg1	extraction					90:99	ultrasound pectin extraction	72:99	ultrasound pectin extraction	72:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	5	65	theme	molecular	876:884	arg1	Mw					894:895	Mw	894:895	Mw	894:895	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	5	65	theme	molecular	876:884	arg1	weight					886:891	the molecular weight	872:891	the molecular weight (Mw) of the extracted pectins (539 kDa)	872:931	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	7	66	theme	capacity	1208:1215	arg1	terms					1177:1181	terms	1177:1181	terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1177:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	2	67	theme	optimization	368:379	arg1	methodology					327:337	Response surface methodology	310:337	Response surface methodology (RSM)	310:343	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	67	theme	optimization	368:379	arg1	tool					381:384	process optimization tool	360:384	process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE)	360:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	0	68	theme	valorization	4:15	arg1	approach					17:24	New valorization approach	0:24	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction	0:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	7	69	theme	oil	1196:1198	arg1	capacity					1208:1215	oil holding capacity	1196:1215	oil holding capacity	1196:1215	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	2	70	theme	ultrasound-assisted	421:439	arg1	UAE					453:455	UAE	453:455	UAE	453:455	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	70	theme	ultrasound-assisted	421:439	arg1	extraction					441:450	ultrasound-assisted extraction	421:450	ultrasound-assisted extraction (UAE)	421:456	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	8	71	theme	FRAP	1403:1406	arg1	assays					1408:1413	FRAP assays	1403:1413	FRAP assays	1403:1413	Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.					
35597379	1	72	theme	Algerian	263:270	arg1	variety					279:285	an Algerian common variety	260:285	an Algerian common variety	260:285	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
35597379	5	73	theme	Conventional	838:849	arg1	treatments					851:860	Conventional treatments	838:860	Conventional treatments	838:860	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	7	74	theme	water	1186:1190	arg1	terms					1177:1181	terms	1177:1181	terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g)	1177:1285	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	0	75	theme	dates	38:42	arg1	approach					17:24	New valorization approach	0:24	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction	0:99	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	0	76	dep	Phoenix	45:51	arg1	L.					65:66	Phoenix dactylifera L.	45:66	Phoenix dactylifera L.	45:66	New valorization approach of Algerian dates (Phoenix dactylifera L.) by ultrasound pectin extraction: Physicochemical, techno-functional, antioxidant and antidiabetic properties.					
35597379	4	77	theme	composition	713:723	arg1	evaluation					685:694	The evaluation	681:694	The evaluation of the monomeric composition	681:723	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	5	78	theme	pectins	915:921	arg1	Mw					894:895	Mw	894:895	Mw	894:895	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	5	78	theme	pectins	915:921	arg1	weight					886:891	the molecular weight	872:891	the molecular weight (Mw) of the extracted pectins (539 kDa)	872:931	Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa).					
35597379	6	79	theme	Spectroscopy	1016:1027	arg1	analysis					1046:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	3	80	theme	optimum	599:605	arg1	conditions					607:616	the optimum conditions	595:616	the optimum conditions (60 °C, 90 min, pH 1.5)	595:640	The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model.					
35597379	4	81	theme	higher	732:737	arg1	content					739:745	higher content	732:745	higher content of galacturonic acid and lower of neutral sugars	732:794	The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin.					
35597379	6	82	theme	Fourier-Transform	989:1005	arg1	FT-IR					1030:1034	FT-IR	1030:1034	FT-IR	1030:1034	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	6	82	theme	Fourier-Transform	989:1005	arg1	Spectroscopy					1016:1027	Fourier-Transform Infrared Spectroscopy	989:1027	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis	989:1053	Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins.					
35597379	2	83	theme	Response	310:317	arg1	methodology					327:337	Response surface methodology	310:337	Response surface methodology (RSM)	310:343	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	83	theme	Response	310:317	arg1	tool					381:384	process optimization tool	360:384	process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE)	360:506	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	2	83	theme	Response	310:317	arg1	RSM					340:342	RSM	340:342	RSM	340:342	Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE).					
35597379	7	84	dep	water	1186:1190	arg1	3.8 g/g					1226:1232	3.8 g/g	1226:1232	3.8 g/g	1226:1232	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	7	84	dep	water	1186:1190	arg1	5.2					1218:1220	5.2	1218:1220	5.2	1218:1220	CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g).					
35597379	1	85	theme	current	228:234	arg1	study					236:240	the current study	224:240	the current study	224:240	To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins.					
36912686	11	0	contain	has	1621:1623	arg1	region					1614:1619	the side region	1605:1619	the side region	1605:1619	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	11	0	contain	has	1621:1623	arg2	crystalline					1627:1637	crystalline	1627:1637	crystalline	1627:1637	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	11	0	contain	has	1621:1623	arg2	amorphous					1642:1650	amorphous	1642:1650	amorphous	1642:1650	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	7	1	theme	calcite	1030:1036	arg1	crystallites					1038:1049	calcite crystallites	1030:1049	calcite crystallites	1030:1049	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	1	2	theme	breaking	138:145	arg1	shells					155:160	breaking mollusc shells	138:160	breaking mollusc shells	138:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	8	3	theme	larger	1096:1101	arg1	crystallites					1111:1122	larger calcite crystallites	1096:1122	larger calcite crystallites	1096:1122	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	11	4	theme	club	1466:1469	arg1	side					1454:1457	the side	1450:1457	the side of the club	1450:1469	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	11	5	theme	phases	1545:1550	arg1	variety					1534:1540	a variety	1532:1540	a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase	1532:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	11	5	theme	phases	1545:1550	arg1	phases					1545:1550	phases	1545:1550	phases	1545:1550	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	8	6	from	present	1187:1193	arg1	biocomposite					1203:1214	this biocomposite	1198:1214	this biocomposite	1198:1214	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	1	7	theme	mollusc	147:153	arg1	shells					155:160	breaking mollusc shells	138:160	breaking mollusc shells	138:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	11	8	theme	side	1609:1612	arg1	region					1614:1619	the side region	1605:1619	the side region	1605:1619	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	4	9	theme	amorphous	471:479	arg1	phases					481:486	more amorphous phases	466:486	more amorphous phases	466:486	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	11	10	dep	crystalline	1627:1637	arg1	phase					1660:1664	mineral phase	1652:1664	mineral phase	1652:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	5	11	theme	striated	657:664	arg1	regions					666:672	the periodic and striated regions	640:672	the periodic and striated regions	640:672	This work focuses on the side of the club, in what is known as the periodic and striated regions.					
36912686	5	12	theme	club	614:617	arg1	side					602:605	the side	598:605	the side of the club, in what is known as the periodic and striated regions	598:672	This work focuses on the side of the club, in what is known as the periodic and striated regions.					
36912686	6	13	theme	diffraction	748:758	arg1	mapping					760:766	synchrotron X-ray diffraction mapping	730:766	synchrotron X-ray diffraction mapping	730:766	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	1	14	theme	dactyl	121:126	arg1	clubs					128:132	its weaponized appendage dactyl clubs	96:132	its weaponized appendage dactyl clubs for breaking mollusc shells	96:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	3	15	theme	impact	319:324	arg1	region					326:331	impact region	319:331	impact region	319:331	Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites.					
36912686	3	15	theme	impact	319:324	arg1	regions					279:285	the regions	275:285	the regions close to the action	275:305	Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites.					
36912686	3	16	theme	Most	246:249	arg1	research					251:258	Most research	246:258	Most research	246:258	Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites.					
36912686	6	17	theme	X-ray	742:746	arg1	mapping					760:766	synchrotron X-ray diffraction mapping	730:766	synchrotron X-ray diffraction mapping	730:766	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	9	18	theme	club	1308:1311	arg1	side					1296:1299	the side	1292:1299	the side of the club	1292:1311	This suggests that chitin may serve as a template for crystallization when the side of the club is fully mineralized.					
36912686	9	18	theme	club	1308:1311	arg1	mineralized					1322:1332	mineralized	1322:1332	mineralized	1322:1332	This suggests that chitin may serve as a template for crystallization when the side of the club is fully mineralized.					
36912686	11	19	theme	safety	1502:1507	arg1	margin					1509:1514	a significant safety margin	1488:1514	a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase	1488:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	7	20	theme	amorphous	1013:1021	arg1	phase					1023:1027	an amorphous phase	1010:1027	an amorphous phase	1010:1027	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	6	21	theme	synchrotron	730:740	arg1	mapping					760:766	synchrotron X-ray diffraction mapping	730:766	synchrotron X-ray diffraction mapping	730:766	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	22	from	region	846:851	arg1	mineral					830:836	mineral	830:836	mineral	830:836	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	4	23	theme	lower	441:445	arg1	mineralization					447:460	lower mineralization	441:460	lower mineralization	441:460	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	8	24	from	biocomposite	1203:1214	arg1	present					1187:1193	present	1187:1193	present	1187:1193	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	1	25	theme	fascinating	67:77	arg1	animal					79:84	a fascinating animal	65:84	a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells	65:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	1	25	theme	fascinating	67:77	arg1	stomatopod					51:60	The stomatopod	47:60	The stomatopod	47:60	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	7	26	theme	side	969:972	arg1	region					974:979	this side region	964:979	this side region	964:979	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	0	27	theme	Flexible	0:7	arg1	design					9:14	Flexible design	0:14	Flexible design	0:14	Flexible design in the stomatopod dactyl club.					
36912686	6	28	theme	tomography	718:727	arg1	combination					677:687	A combination	675:687	A combination of laboratory micro-computed tomography	675:727	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	28	theme	tomography	718:727	arg1	mapping					803:809	synchrotron X-ray fluorescence mapping	772:809	synchrotron X-ray fluorescence mapping	772:809	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	28	theme	tomography	718:727	arg1	mapping					760:766	synchrotron X-ray diffraction mapping	730:766	synchrotron X-ray diffraction mapping	730:766	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	8	29	dep	organized	1139:1147	arg1	textured					1150:1157	textured	1150:1157	textured	1150:1157	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	7	30	theme	both	1067:1070	arg1	mixture					1056:1062	a mixture	1054:1062	a mixture of both	1054:1070	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	7	30	theme	both	1067:1070	arg1	phase					1023:1027	an amorphous phase	1010:1027	an amorphous phase	1010:1027	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	7	30	theme	both	1067:1070	arg1	crystallites					1038:1049	calcite crystallites	1030:1049	calcite crystallites	1030:1049	This means that this side region can be mineralized by either an amorphous phase, calcite crystallites or a mixture of both.					
36912686	8	31	theme	present	1187:1193	arg1	chitin					1180:1185	the chitin	1176:1185	the chitin present in this biocomposite	1176:1214	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	6	32	from	phase	913:917	arg1	clubs					941:945	clubs	941:945	clubs	941:945	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	32	from	phase	913:917	arg1	all					936:938	all	936:938	all	936:938	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	32	from	phase	913:917	arg1	some					922:925	some	922:925	some	922:925	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	6	33	theme	micro-computed	703:716	arg1	tomography					718:727	laboratory micro-computed tomography	692:727	laboratory micro-computed tomography	692:727	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	4	34	theme	impact	420:425	arg1	impact					420:425	impact	420:425	impact	420:425	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	4	34	theme	impact	420:425	arg1	site					412:415	the site	408:415	the site of impact	408:425	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	0	35	theme	dactyl	34:39	arg1	club					41:44	the stomatopod dactyl club	19:44	the stomatopod dactyl club	19:44	Flexible design in the stomatopod dactyl club.					
36912686	6	36	theme	crystalline	901:911	arg1	phase					913:917	a crystalline phase	899:917	a crystalline phase in some, but not all, clubs	899:945	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	2	37	theme	Dactyl	163:168	arg1	example					195:201	a well studied example	180:201	a well studied example of biomineralized hierarchical structures	180:243	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	2	37	theme	Dactyl	163:168	arg1	clubs					170:174	Dactyl clubs	163:174	Dactyl clubs	163:174	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	2	38	theme	hierarchical	221:232	arg1	structures					234:243	biomineralized hierarchical structures	206:243	biomineralized hierarchical structures	206:243	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	0	39	theme	stomatopod	23:32	arg1	club					41:44	the stomatopod dactyl club	19:44	the stomatopod dactyl club	19:44	Flexible design in the stomatopod dactyl club.					
36912686	11	40	theme	mineral	1652:1658	arg1	phase					1660:1664	mineral phase	1652:1664	mineral phase	1652:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	5	41	theme	periodic	644:651	arg1	regions					666:672	the periodic and striated regions	640:672	the periodic and striated regions	640:672	This work focuses on the side of the club, in what is known as the periodic and striated regions.					
36912686	2	42	theme	biomineralized	206:219	arg1	structures					234:243	biomineralized hierarchical structures	206:243	biomineralized hierarchical structures	206:243	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	6	43	theme	laboratory	692:701	arg1	tomography					718:727	laboratory micro-computed tomography	692:727	laboratory micro-computed tomography	692:727	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	3	44	theme	apatite	368:374	arg1	crystallites					376:387	apatite crystallites	368:387	apatite crystallites	368:387	Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites.					
36912686	6	45	from	amorphous	886:894	arg1	transition					867:876	the transition	863:876	the transition from an amorphous to a crystalline phase in some, but not all, clubs	863:945	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	8	46	attach	present	1187:1193	arg1	biocomposite					1203:1214	this biocomposite	1198:1214	this biocomposite	1198:1214	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	8	46	attach	present	1187:1193	arg2	chitin					1180:1185	the chitin	1176:1185	the chitin present in this biocomposite	1176:1214	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	3	47	dep	region	326:331	arg1	the					315:317	the	315:317	the	315:317	Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites.					
36912686	2	48	theme	studied	187:193	arg1	example					195:201	a well studied example	180:201	a well studied example of biomineralized hierarchical structures	180:243	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	2	48	theme	studied	187:193	arg1	clubs					170:174	Dactyl clubs	163:174	Dactyl clubs	163:174	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	11	49	dep	club	1562:1565	arg1	function					1571:1578	function	1571:1578	can function independently of whether the side region has a crystalline or amorphous mineral phase	1567:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	11	49	dep	club	1562:1565	arg1	i.e.					1553:1556	i.e.	1553:1556	i.e.	1553:1556	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	8	50	theme	calcite	1103:1109	arg1	crystallites					1111:1122	larger calcite crystallites	1096:1122	larger calcite crystallites	1096:1122	It was found that when larger calcite crystallites form, they are organized (textured) with respect to the chitin present in this biocomposite.					
36912686	1	51	theme	weaponized	100:109	arg1	clubs					128:132	its weaponized appendage dactyl clubs	96:132	its weaponized appendage dactyl clubs for breaking mollusc shells	96:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	6	52	theme	fluorescence	790:801	arg1	mapping					803:809	synchrotron X-ray fluorescence mapping	772:809	synchrotron X-ray fluorescence mapping	772:809	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	1	53	theme	appendage	111:119	arg1	clubs					128:132	its weaponized appendage dactyl clubs	96:132	its weaponized appendage dactyl clubs for breaking mollusc shells	96:160	The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells.					
36912686	6	54	theme	X-ray	784:788	arg1	mapping					803:809	synchrotron X-ray fluorescence mapping	772:809	synchrotron X-ray fluorescence mapping	772:809	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	10	55	theme	calcite	1344:1350	arg1	crystallites					1352:1363	calcite crystallites	1344:1363	calcite crystallites	1344:1363	Further, calcite crystallites were found to form as early as 1 week after moulting of the club.					
36912686	4	56	contain	has	437:439	arg2	phases					481:486	more amorphous phases	466:486	more amorphous phases	466:486	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	4	56	contain	has	437:439	arg1	club					432:435	the club	428:435	the club	428:435	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	4	56	contain	has	437:439	arg2	mineralization					447:460	lower mineralization	441:460	lower mineralization	441:460	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	11	57	theme	significant	1490:1500	arg1	margin					1509:1514	a significant safety margin	1488:1514	a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase	1488:1664	This suggests that the side of the club is designed with a significant safety margin that allows for a variety of phases, i.e. the club can function independently of whether the side region has a crystalline or amorphous mineral phase.					
36912686	4	58	theme	mineralized	551:561	arg1	areas					495:499	these areas	489:499	these areas	489:499	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	4	58	theme	mineralized	551:561	arg1	counterparts					563:574	their highly mineralized counterparts	538:574	their highly mineralized counterparts	538:574	Further away from the site of impact, the club has lower mineralization and more amorphous phases; these areas have not been as actively studied as their highly mineralized counterparts.					
36912686	6	59	theme	synchrotron	772:782	arg1	mapping					803:809	synchrotron X-ray fluorescence mapping	772:809	synchrotron X-ray fluorescence mapping	772:809	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
36912686	0	60	dep	design	9:14	arg1	club					41:44	the stomatopod dactyl club	19:44	the stomatopod dactyl club	19:44	Flexible design in the stomatopod dactyl club.					
36912686	10	61	theme	club	1425:1428	arg1	moulting					1409:1416	moulting	1409:1416	moulting of the club	1409:1428	Further, calcite crystallites were found to form as early as 1 week after moulting of the club.					
36912686	2	62	theme	structures	234:243	arg1	example					195:201	a well studied example	180:201	a well studied example of biomineralized hierarchical structures	180:243	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	2	62	theme	structures	234:243	arg1	clubs					170:174	Dactyl clubs	163:174	Dactyl clubs	163:174	Dactyl clubs are a well studied example of biomineralized hierarchical structures.					
36912686	6	63	from	mineral	830:836	arg1	region					846:851	this region	841:851	this region	841:851	A combination of laboratory micro-computed tomography, synchrotron X-ray diffraction mapping and synchrotron X-ray fluorescence mapping has shown that the mineral in this region undergoes the transition from an amorphous to a crystalline phase in some, but not all, clubs.					
35567682	1	0	theme	Si-OH	164:168	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	0	theme	Si-OH	164:168	arg1	CS-Glu					170:175	Fe3O4@Si-OH@CS-Glu	158:175	Fe3O4@Si-OH@CS-Glu	158:175	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	2	1	theme	zeta	453:456	arg1	potential					458:466	zeta potential	453:466	zeta potential	453:466	The adsorbent was characterised with SEM, XRD, FTIR, BET, VSM, and zeta potential.					
35567682	1	2	theme	@	169:169	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	2	theme	@	169:169	arg1	CS-Glu					170:175	Fe3O4@Si-OH@CS-Glu	158:175	Fe3O4@Si-OH@CS-Glu	158:175	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	6	3	theme	adsorbent	949:957	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	1	4	used	used	315:318	arg2	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	4	used	used	315:318	arg2	agent					251:255	a cross-linking agent	235:255	a cross-linking agent	235:255	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	5	theme	improved	268:275	arg1	properties					293:302	improved physicochemical properties	268:302	improved physicochemical properties	268:302	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	6	6	theme	stable	1021:1026	arg1	structure					1028:1036	a stable structure	1019:1036	a stable structure	1019:1036	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	4	7	theme	adsorption	749:758	arg1	cycles					760:765	2-4 adsorption cycles	745:765	2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu	745:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	7	8	theme	heavy	1108:1112	arg1	metals					1114:1119	heavy metals	1108:1119	heavy metals	1108:1119	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	3	9	theme	Fe3O4	526:530	arg1	CS-Glu					538:543	Fe3O4@Si-OH@CS-Glu	526:543	Fe3O4@Si-OH@CS-Glu	526:543	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	1	10	theme	physicochemical	277:291	arg1	properties					293:302	improved physicochemical properties	268:302	improved physicochemical properties	268:302	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	11	theme	polluted	370:377	arg1	water					379:383	polluted water	370:383	polluted water	370:383	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	5	12	theme	main	803:806	arg1	mechanism					819:827	The main adsorption mechanism	799:827	The main adsorption mechanism of the adsorbent for heavy metals and bacteria	799:874	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	5	12	theme	main	803:806	arg1	adsorption					893:902	electrostatic adsorption	879:902	electrostatic adsorption	879:902	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	3	13	theme	adsorption	499:508	arg1	high					584:587	high	584:587	high	584:587	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	3	13	theme	adsorption	499:508	arg1	efficiencies					510:521	the adsorption efficiencies	495:521	the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+	495:574	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	6	14	theme	@	941:941	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	6	15	theme	Si-OH	936:940	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	0	16	theme	bacteria	98:105	arg1	removal					70:76	removal	70:76	removal of heavy metals and bacteria	70:105	Glutaraldehyde base-cross-linked chitosan-silanol/Fe3O4 composite for removal of heavy metals and bacteria.					
35567682	3	17	theme	@	537:537	arg1	CS-Glu					538:543	Fe3O4@Si-OH@CS-Glu	526:543	Fe3O4@Si-OH@CS-Glu	526:543	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	6	18	theme	@	935:935	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	7	19	from	water	1139:1143	arg1	removal					1097:1103	the removal	1093:1103	the removal of heavy metals and bacteria from water	1093:1143	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	3	20	theme	CS-Glu	538:543	arg1	high					584:587	high	584:587	high	584:587	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	3	20	theme	CS-Glu	538:543	arg1	efficiencies					510:521	the adsorption efficiencies	495:521	the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+	495:574	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	1	21	theme	chitosan-silanol	188:203	arg1	groups					205:210	chitosan-silanol groups	188:210	chitosan-silanol groups	188:210	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	4	22	theme	@	790:790	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	3	23	theme	@	531:531	arg1	CS-Glu					538:543	Fe3O4@Si-OH@CS-Glu	526:543	Fe3O4@Si-OH@CS-Glu	526:543	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	6	24	theme	synthesised	918:928	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	0	25	theme	chitosan-silanol/Fe3O4	33:54	arg1	composite					56:64	chitosan-silanol/Fe3O4 composite	33:64	chitosan-silanol/Fe3O4 composite	33:64	Glutaraldehyde base-cross-linked chitosan-silanol/Fe3O4 composite for removal of heavy metals and bacteria.					
35567682	4	26	theme	Si-OH	785:789	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	3	27	theme	Si-OH	532:536	arg1	CS-Glu					538:543	Fe3O4@Si-OH@CS-Glu	526:543	Fe3O4@Si-OH@CS-Glu	526:543	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	4	28	dep	coli	661:664	arg1	gram-negative					667:679	gram-negative	667:679	gram-negative	667:679	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	3	29	theme	optimum	475:481	arg1	conditions					483:492	optimum conditions	475:492	optimum conditions	475:492	Under optimum conditions, the adsorption efficiencies of Fe3O4@Si-OH@CS-Glu for Cr6+, As5+, Hg2+, and Se6+ were as high as 90.5%, 73.5%, 91.6%, and 100% respectively.					
35567682	7	30	theme	metals	1114:1119	arg1	removal					1097:1103	the removal	1093:1103	the removal of heavy metals and bacteria from water	1093:1143	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	6	31	theme	Fe3O4	930:934	arg1	CS-Glu					942:947	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	the synthesised Fe3O4@Si-OH@CS-Glu adsorbent	914:957	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	5	32	theme	electrostatic	879:891	arg1	mechanism					819:827	The main adsorption mechanism	799:827	The main adsorption mechanism of the adsorbent for heavy metals and bacteria	799:874	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	5	32	theme	electrostatic	879:891	arg1	adsorption					893:902	electrostatic adsorption	879:902	electrostatic adsorption	879:902	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	0	33	theme	heavy	81:85	arg1	metals					87:92	heavy metals	81:92	heavy metals	81:92	Glutaraldehyde base-cross-linked chitosan-silanol/Fe3O4 composite for removal of heavy metals and bacteria.					
35567682	4	34	theme	2.5 mg	772:777	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	6	35	theme	high	966:969	arg1	efficiency					979:988	high removal efficiency	966:988	high removal efficiency	966:988	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	6	36	theme	adsorption	994:1003	arg1	capacity					1005:1012	adsorption capacity	994:1012	adsorption capacity	994:1012	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	6	37	theme	easy	1042:1045	arg1	separation					1047:1056	easy separation	1042:1056	easy separation	1042:1056	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	4	38	with	cycles	760:765	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	1	39	theme	multiple	330:337	arg1	metals					345:350	multiple heavy metals	330:350	multiple heavy metals	330:350	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	4	40	theme	@	784:784	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	5	41	theme	heavy	850:854	arg1	metals					856:861	heavy metals	850:861	heavy metals	850:861	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	7	42	contain	has	1062:1064	arg1	It					1059:1060	It	1059:1060	It	1059:1060	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	7	42	contain	has	1062:1064	arg2	applications					1076:1087	promising applications	1066:1087	promising applications	1066:1087	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	7	43	theme	bacteria	1125:1132	arg1	removal					1097:1103	the removal	1093:1103	the removal of heavy metals and bacteria from water	1093:1143	It has promising applications for the removal of heavy metals and bacteria from water.					
35567682	5	44	theme	adsorption	808:817	arg1	mechanism					819:827	The main adsorption mechanism	799:827	The main adsorption mechanism of the adsorbent for heavy metals and bacteria	799:874	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	5	44	theme	adsorption	808:817	arg1	adsorption					893:902	electrostatic adsorption	879:902	electrostatic adsorption	879:902	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	4	45	theme	Fe3O4	779:783	arg1	CS-Glu					791:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	2.5 mg Fe3O4@Si-OH@CS-Glu	772:796	In addition, Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) can be removed after 2-4 adsorption cycles with 2.5 mg Fe3O4@Si-OH@CS-Glu.					
35567682	6	46	theme	removal	971:977	arg1	efficiency					979:988	high removal efficiency	966:988	high removal efficiency	966:988	Overall, the synthesised Fe3O4@Si-OH@CS-Glu adsorbent showed high removal efficiency and adsorption capacity with a stable structure and easy separation.					
35567682	1	47	theme	cross-linking	237:249	arg1	agent					251:255	a cross-linking agent	235:255	a cross-linking agent	235:255	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	47	theme	cross-linking	237:249	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	5	48	theme	adsorbent	836:844	arg1	mechanism					819:827	The main adsorption mechanism	799:827	The main adsorption mechanism of the adsorbent for heavy metals and bacteria	799:874	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	5	48	theme	adsorbent	836:844	arg1	adsorption					893:902	electrostatic adsorption	879:902	electrostatic adsorption	879:902	The main adsorption mechanism of the adsorbent for heavy metals and bacteria is electrostatic adsorption.					
35567682	1	49	contain	has	264:266	arg1	agent					251:255	a cross-linking agent	235:255	a cross-linking agent	235:255	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	49	contain	has	264:266	arg2	properties					293:302	improved physicochemical properties	268:302	improved physicochemical properties	268:302	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	49	contain	has	264:266	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	50	theme	Fe3O4	158:162	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	50	theme	Fe3O4	158:162	arg1	CS-Glu					170:175	Fe3O4@Si-OH@CS-Glu	158:175	Fe3O4@Si-OH@CS-Glu	158:175	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	0	51	theme	metals	87:92	arg1	removal					70:76	removal	70:76	removal of heavy metals and bacteria	70:105	Glutaraldehyde base-cross-linked chitosan-silanol/Fe3O4 composite for removal of heavy metals and bacteria.					
35567682	1	52	theme	heavy	339:343	arg1	metals					345:350	multiple heavy metals	330:350	multiple heavy metals	330:350	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	53	theme	@	163:163	arg1	adsorbent					147:155	adsorbent	147:155	adsorbent	147:155	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	1	53	theme	@	163:163	arg1	CS-Glu					170:175	Fe3O4@Si-OH@CS-Glu	158:175	Fe3O4@Si-OH@CS-Glu	158:175	We designed and synthesised a magnetic adsorbent (Fe3O4@Si-OH@CS-Glu) combining chitosan-silanol groups with glutaraldehyde as a cross-linking agent, which has improved physicochemical properties and can be used to remove multiple heavy metals and bacteria from polluted water.					
35567682	7	54	theme	promising	1066:1074	arg1	applications					1076:1087	promising applications	1066:1087	promising applications	1066:1087	It has promising applications for the removal of heavy metals and bacteria from water.					
36500331	6	0	theme	biocomposite	944:955	arg1	characterization					918:933	The characterization	914:933	The characterization of novel biocomposite (HEC/PANI-PPy)	914:970	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	3	1	theme	recent	468:473	arg1	years					475:479	recent years	468:479	recent years	468:479	In recent years, nanomaterials have become attractive choice for eco-friendly removal of organic dyestuff.					
36500331	7	2	theme	contact	1228:1234	arg1	time					1236:1239	contact time	1228:1239	contact time	1228:1239	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	4	3	theme	wherein	653:659	arg1	copolymer					661:669	biocomposite wherein copolymer	640:669	biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY)	640:713	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	0	4	theme	Polyaniline	83:93	arg1	Copolymer					70:78	Copolymer	70:78	Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes	70:145	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	5	5	theme	textile	839:845	arg1	B					862:862	Rhodamine B	852:862	Rhodamine B (RhB)	852:868	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	5	theme	textile	839:845	arg1	dyes					847:850	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	5	theme	textile	839:845	arg1	Orange					881:886	methyl Orange	874:886	methyl Orange (MO)-	874:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	3	6	theme	dyestuff	562:569	arg1	removal					543:549	eco-friendly removal	530:549	eco-friendly removal of organic dyestuff	530:569	In recent years, nanomaterials have become attractive choice for eco-friendly removal of organic dyestuff.					
36500331	1	7	theme	aquatic	285:291	arg1	environment					293:303	the aquatic environment	281:303	the aquatic environment	281:303	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	0	8	theme	Biocomposite	111:122	arg1	Copolymer					70:78	Copolymer	70:78	Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes	70:145	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	10	9	theme	dyes	1703:1706	arg1	removal					1678:1684	removal	1678:1684	removal	1678:1684	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	10	9	theme	dyes	1703:1706	arg1	separation					1663:1672	separation	1663:1672	separation	1663:1672	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	2	10	from	processes	355:363	arg1	textiles					368:375	textiles	368:375	textiles	368:375	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	1	11	theme	sustainable	173:183	arg1	textiles					185:192	sustainable textiles	173:192	sustainable textiles	173:192	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	7	12	theme	adsorbent	1203:1211	arg1	amount					1213:1218	adsorbent amount	1203:1218	adsorbent amount	1203:1218	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	3	13	theme	eco-friendly	530:541	arg1	removal					543:549	eco-friendly removal	530:549	eco-friendly removal of organic dyestuff	530:569	In recent years, nanomaterials have become attractive choice for eco-friendly removal of organic dyestuff.					
36500331	7	14	theme	initial	1180:1186	arg1	concentration					1188:1200	dye initial concentration	1176:1200	dye initial concentration	1176:1200	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	9	15	theme	adsorption	1462:1471	arg1	capacity					1473:1480	the adsorption capacity	1458:1480	the adsorption capacity HEC/PANI-PPy	1458:1493	It is found that the adsorption capacity HEC/PANI-PPy is 30.06 and 29.3 for RhB and MO respectively.					
36500331	1	16	theme	controlled	198:207	arg1	production					209:218	controlled production	198:218	controlled production	198:218	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	1	17	theme	textiles	185:192	arg1	concepts					161:168	The emerging concepts	148:168	The emerging concepts of sustainable textiles	148:192	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	1	17	theme	textiles	185:192	arg1	production					209:218	controlled production	198:218	controlled production	198:218	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	5	18	theme	as-prepared	796:806	arg1	composite					808:816	as-prepared composite	796:816	as-prepared composite	796:816	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	19	theme	methyl	874:879	arg1	MO					889:890	MO	889:890	MO	889:890	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	19	theme	methyl	874:879	arg1	Orange					881:886	methyl Orange	874:886	methyl Orange (MO)-	874:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	19	theme	methyl	874:879	arg1	dyes					847:850	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	7	20	theme	dye	1176:1178	arg1	concentration					1188:1200	dye initial concentration	1176:1200	dye initial concentration	1176:1200	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	2	21	theme	synthetic	436:444	arg1	dyes					446:449	super toxic synthetic dyes	424:449	super toxic synthetic dyes	424:449	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	8	22	theme	RhB	1374:1376	arg1	adsorption					1360:1369	the composite-mediated adsorption	1337:1369	the composite-mediated adsorption of RhB and MO	1337:1383	Interestingly, the composite-mediated adsorption of RhB and MO followed pseudo-second order and the Langmuir isotherm.					
36500331	2	23	theme	toxic	430:434	arg1	dyes					446:449	super toxic synthetic dyes	424:449	super toxic synthetic dyes	424:449	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	6	24	theme	novel	938:942	arg1	HEC/PANI-PPy					958:969	HEC/PANI-PPy	958:969	HEC/PANI-PPy	958:969	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	24	theme	novel	938:942	arg1	biocomposite					944:955	novel biocomposite	938:955	novel biocomposite (HEC/PANI-PPy)	938:970	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	7	25	theme	operational	1145:1155	arg1	pH					1221:1222	pH	1221:1222	pH	1221:1222	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	7	25	theme	operational	1145:1155	arg1	amount					1213:1218	adsorbent amount	1203:1218	adsorbent amount	1203:1218	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	7	25	theme	operational	1145:1155	arg1	time					1236:1239	contact time	1228:1239	contact time	1228:1239	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	7	25	theme	operational	1145:1155	arg1	parameters					1157:1166	The operational parameters	1141:1166	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time	1141:1239	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	7	25	theme	operational	1145:1155	arg1	concentration					1188:1200	dye initial concentration	1176:1200	dye initial concentration	1176:1200	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	5	26	dep	dyes	847:850	arg1	RhB					865:867	RhB	865:867	RhB	865:867	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	26	dep	dyes	847:850	arg1	MO					889:890	MO	889:890	MO	889:890	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	26	dep	dyes	847:850	arg1	B					862:862	Rhodamine B	852:862	Rhodamine B (RhB)	852:868	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	26	dep	dyes	847:850	arg1	Orange					881:886	methyl Orange	874:886	methyl Orange (MO)-	874:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	26	dep	dyes	847:850	arg1	dyes					847:850	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	2	27	theme	super	424:428	arg1	dyes					446:449	super toxic synthetic dyes	424:449	super toxic synthetic dyes	424:449	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	0	28	theme	Dyes	142:145	arg1	Adsorption					128:137	Adsorption	128:137	Adsorption of Dyes	128:145	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	7	29	theme	biocomposite	1308:1319	arg1	level					1286:1290	the efficiency level	1271:1290	the efficiency level of the prepared biocomposite	1271:1319	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	2	30	theme	conventional	342:353	arg1	processes					355:363	the currently in-practiced conventional processes	315:363	the currently in-practiced conventional processes in textiles	315:375	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	3	31	theme	attractive	508:517	arg1	choice					519:524	attractive choice	508:524	attractive choice for eco-friendly removal of organic dyestuff	508:569	In recent years, nanomaterials have become attractive choice for eco-friendly removal of organic dyestuff.					
36500331	6	32	theme	X-ray	1116:1120	arg1	diffraction					1122:1132	powder X-ray diffraction	1109:1132	powder X-ray diffraction (XRD)	1109:1138	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	32	theme	X-ray	1116:1120	arg1	XRD					1135:1137	XRD	1135:1137	XRD	1135:1137	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	10	33	theme	textile	1722:1728	arg1	effluents					1730:1738	polluted textile effluents	1713:1738	polluted textile effluents	1713:1738	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	2	34	theme	in-practiced	329:340	arg1	processes					355:363	the currently in-practiced conventional processes	315:363	the currently in-practiced conventional processes in textiles	315:375	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	6	35	theme	powder	1109:1114	arg1	diffraction					1122:1132	powder X-ray diffraction	1109:1132	powder X-ray diffraction (XRD)	1109:1138	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	35	theme	powder	1109:1114	arg1	XRD					1135:1137	XRD	1135:1137	XRD	1135:1137	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	0	36	theme	Cellulose	47:55	arg1	Characterization					14:29	Characterization	14:29	Characterization	14:29	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	0	36	theme	Cellulose	47:55	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis	0:8	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	10	37	dep	inexpensive	1567:1577	arg1	adsorbent					1600:1608	adsorbent	1600:1608	adsorbent	1600:1608	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	9	38	theme	capacity	1473:1480	arg1	HEC/PANI-PPy					1482:1493	the adsorption capacity HEC/PANI-PPy	1458:1493	the adsorption capacity HEC/PANI-PPy	1458:1493	It is found that the adsorption capacity HEC/PANI-PPy is 30.06 and 29.3 for RhB and MO respectively.					
36500331	8	39	theme	pseudo-second	1394:1406	arg1	order					1408:1412	pseudo-second order	1394:1412	pseudo-second order	1394:1412	Interestingly, the composite-mediated adsorption of RhB and MO followed pseudo-second order and the Langmuir isotherm.					
36500331	1	40	theme	production	209:218	arg1	strategy					220:227	The emerging concepts of sustainable textiles and controlled production strategy	148:227	The emerging concepts of sustainable textiles and controlled production strategy	148:227	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	7	41	theme	efficiency	1275:1284	arg1	level					1286:1290	the efficiency level	1271:1290	the efficiency level of the prepared biocomposite	1271:1319	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	0	42	theme	Hydroxyethyl	34:45	arg1	Cellulose					47:55	Hydroxyethyl Cellulose	34:55	Hydroxyethyl Cellulose	34:55	Synthesis and Characterization of Hydroxyethyl Cellulose Grafted with Copolymer of Polyaniline and Polypyrrole Biocomposite for Adsorption of Dyes.					
36500331	4	43	theme	biocomposite	640:651	arg1	copolymer					661:669	biocomposite wherein copolymer	640:669	biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY)	640:713	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	6	44	theme	Brunauer-Emmett-Teller	1030:1051	arg1	BET					1063:1065	BET	1063:1065	BET	1063:1065	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	44	theme	Brunauer-Emmett-Teller	1030:1051	arg1	analyzer					1053:1060	Brunauer-Emmett-Teller analyzer	1030:1060	Brunauer-Emmett-Teller analyzer (BET)	1030:1066	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	5	45	theme	Rhodamine	852:860	arg1	RhB					865:867	RhB	865:867	RhB	865:867	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	45	theme	Rhodamine	852:860	arg1	B					862:862	Rhodamine B	852:862	Rhodamine B (RhB)	852:868	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	45	theme	Rhodamine	852:860	arg1	dyes					847:850	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	textile dyes Rhodamine B (RhB) and methyl Orange (MO)-	839:892	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	5	46	theme	adsorption	771:780	arg1	properties					782:791	adsorption properties	771:791	adsorption properties of as-prepared composite	771:816	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	10	47	theme	organic	1695:1701	arg1	dyes					1703:1706	toxic organic dyes	1689:1706	toxic organic dyes	1689:1706	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	10	48	theme	polluted	1713:1720	arg1	effluents					1730:1738	polluted textile effluents	1713:1738	polluted textile effluents	1713:1738	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	6	49	theme	Electron	1078:1085	arg1	Microscope					1087:1096	Scanning Electron Microscope	1069:1096	Scanning Electron Microscope (SEM)	1069:1102	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	49	theme	Electron	1078:1085	arg1	SEM					1099:1101	SEM	1099:1101	SEM	1099:1101	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	10	50	dep	separation	1663:1672	arg1	the					1659:1661	the	1659:1661	the	1659:1661	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	10	51	theme	toxic	1689:1693	arg1	dyes					1703:1706	toxic organic dyes	1689:1706	toxic organic dyes	1689:1706	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	8	52	theme	Langmuir	1422:1429	arg1	isotherm					1431:1438	the Langmuir isotherm	1418:1438	the Langmuir isotherm	1418:1438	Interestingly, the composite-mediated adsorption of RhB and MO followed pseudo-second order and the Langmuir isotherm.					
36500331	4	53	theme	hydroxyethyl	732:743	arg1	HEC					756:758	HEC	756:758	HEC	756:758	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	4	53	theme	hydroxyethyl	732:743	arg1	cellulose					745:753	hydroxyethyl cellulose	732:753	hydroxyethyl cellulose (HEC)	732:759	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	5	54	theme	model	897:901	arg1	adsorbate					903:911	model adsorbate	897:911	model adsorbate	897:911	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	8	55	theme	composite-mediated	1341:1358	arg1	adsorption					1360:1369	the composite-mediated adsorption	1337:1369	the composite-mediated adsorption of RhB and MO	1337:1383	Interestingly, the composite-mediated adsorption of RhB and MO followed pseudo-second order and the Langmuir isotherm.					
36500331	6	56	theme	Scanning	1069:1076	arg1	Microscope					1087:1096	Scanning Electron Microscope	1069:1096	Scanning Electron Microscope (SEM)	1069:1102	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	6	56	theme	Scanning	1069:1076	arg1	SEM					1099:1101	SEM	1099:1101	SEM	1099:1101	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	1	57	theme	concepts	161:168	arg1	strategy					220:227	The emerging concepts of sustainable textiles and controlled production strategy	148:227	The emerging concepts of sustainable textiles and controlled production strategy	148:227	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	7	58	theme	prepared	1299:1306	arg1	biocomposite					1308:1319	the prepared biocomposite	1295:1319	the prepared biocomposite	1295:1319	The operational parameters such as dye initial concentration, adsorbent amount, pH and contact time were also studied to evaluate the efficiency level of the prepared biocomposite.					
36500331	4	59	theme	polyaniline	674:684	arg1	copolymer					661:669	biocomposite wherein copolymer	640:669	biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY)	640:713	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	5	60	theme	composite	808:816	arg1	properties					782:791	adsorption properties	771:791	adsorption properties of as-prepared composite	771:816	Further, adsorption properties of as-prepared composite were evaluated using textile dyes Rhodamine B (RhB) and methyl Orange (MO)- as model adsorbate.					
36500331	6	61	dep	Fourier	994:1000	arg1	Transform					1002:1010	Transform	1002:1010	Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD)	1002:1138	The characterization of novel biocomposite (HEC/PANI-PPy) was carried out using Fourier Transform Infrared (FT-IR), Brunauer-Emmett-Teller analyzer (BET), Scanning Electron Microscope (SEM), and powder X-ray diffraction (XRD).					
36500331	2	62	dep	dyes	446:449	arg1	effluents					454:462	effluents	454:462	effluents	454:462	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	4	63	theme	Polypyrrole	697:707	arg1	copolymer					661:669	biocomposite wherein copolymer	640:669	biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY)	640:713	Accordingly, this article reports synthesis and characterization of biocomposite wherein copolymer of polyaniline (PANI) and Polypyrrole (PPY) was grafted onto hydroxyethyl cellulose (HEC).					
36500331	1	64	theme	emerging	152:159	arg1	concepts					161:168	The emerging concepts	148:168	The emerging concepts of sustainable textiles	148:192	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	8	65	theme	MO	1382:1383	arg1	adsorption					1360:1369	the composite-mediated adsorption	1337:1369	the composite-mediated adsorption of RhB and MO	1337:1383	Interestingly, the composite-mediated adsorption of RhB and MO followed pseudo-second order and the Langmuir isotherm.					
36500331	1	66	theme	contaminants	263:274	arg1	emissions					250:258	ideally zero emissions	237:258	ideally zero emissions of contaminants into the aquatic environment	237:303	The emerging concepts of sustainable textiles and controlled production strategy demands ideally zero emissions of contaminants into the aquatic environment.					
36500331	2	67	theme	contaminants	400:411	arg1	number					390:395	a number	388:395	a number of contaminants especially super toxic synthetic dyes as effluents	388:462	However, the currently in-practiced conventional processes in textiles dispose of a number of contaminants especially super toxic synthetic dyes as effluents.					
36500331	10	68	from	effluents	1730:1738	arg1	removal					1678:1684	removal	1678:1684	removal	1678:1684	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36500331	10	68	from	effluents	1730:1738	arg1	separation					1663:1672	separation	1663:1672	separation	1663:1672	Thus, HEC/PANI-PPy is an inexpensive and highly efficient adsorbent that could be employed for could be employed for the separation and removal of toxic organic dyes from polluted textile effluents.					
36079712	6	0	theme	thickeners	853:862	arg1	viscosity					830:838	The viscosity	826:838	The viscosity of gum-based thickeners	826:862	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	8	1	contain	have	1064:1067	arg2	behavior					1090:1097	a predictable linear behavior	1069:1097	a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener	1069:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	8	1	contain	have	1064:1067	arg1	thickeners					1053:1062	Gum-based thickeners	1043:1062	Gum-based thickeners	1043:1062	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	3	2	theme	thickeners	470:479	arg1	viscosity					447:455	the viscosity	443:455	the viscosity of gum-based thickeners	443:479	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	6	3	theme	gum-based	843:851	arg1	thickeners					853:862	gum-based thickeners	843:862	gum-based thickeners	843:862	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	6	4	theme	preparation	908:918	arg1	h					903:903	6 h	901:903	6 h of preparation	901:918	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	8	5	theme	linear	1083:1088	arg1	behavior					1090:1097	a predictable linear behavior	1069:1097	a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener	1069:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	3	6	theme	thick	640:644	arg1	textures					646:653	very thick textures	635:653	very thick textures	635:653	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	2	7	dep	market	357:362	arg1	gum					395:397	gum	395:397	gum	395:397	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	7	dep	market	357:362	arg1	starch					373:378	starch	373:378	starch	373:378	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	7	dep	market	357:362	arg1	starch					365:370	starch	365:370	starch	365:370	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	4	8	theme	different	684:692	arg1	concentrations					694:707	different concentrations	684:707	different concentrations of the four thickeners using regression analysis (R2 > 0.9)	684:767	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	9	9	theme	pudding-like	1328:1339	arg1	viscosity					1341:1349	pudding-like viscosity	1328:1349	pudding-like viscosity	1328:1349	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	6	10	dep	43	970:971	arg1	to					967:968	to	967:968	to	967:968	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	2	11	from	variations	205:214	arg1	water					232:236	water	232:236	water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	232:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	11	from	variations	205:214	arg1	concentrations					251:264	different concentrations	241:264	different concentrations	241:264	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	11	from	variations	205:214	arg1	evolution					270:278	evolution	270:278	evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	270:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	7	12	theme	correct	1008:1014	arg1	handling					1016:1023	correct handling	1008:1023	correct handling	1008:1023	These findings are important for correct handling and prescription.					
36079712	0	13	theme	Rheological	0:10	arg1	Properties					12:21	Rheological Properties	0:21	Rheological Properties	0:21	Rheological Properties and Stability of Thickeners for Clinical Use.					
36079712	8	14	theme	honey-like	1148:1157	arg1	textures					1159:1166	nectar and honey-like textures	1137:1166	nectar and honey-like textures	1137:1166	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	8	15	with	behavior	1090:1097	arg1	formula					1108:1114	the formula we present, reaching nectar and honey-like textures with less quantity of thickener	1104:1198	the formula we present, reaching nectar and honey-like textures with less quantity of thickener	1104:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	2	16	theme	commercial	319:328	arg1	thickeners					330:339	commercial thickeners	319:339	commercial thickeners that are on the market (starch, starch with gums, and gum)	319:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	8	17	theme	less	1173:1176	arg1	quantity					1178:1185	less quantity	1173:1185	less quantity of thickener	1173:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	1	18	with	patients	99:106	arg1	dysphagia					113:121	dysphagia	113:121	dysphagia	113:121	The adaptation of liquids for patients with dysphagia requires precision and individualization in the viscosities used.					
36079712	1	19	theme	liquids	87:93	arg1	adaptation					73:82	The adaptation	69:82	The adaptation of liquids for patients with dysphagia	69:121	The adaptation of liquids for patients with dysphagia requires precision and individualization in the viscosities used.					
36079712	2	20	from	concentrations	251:264	arg1	water					232:236	water	232:236	water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	232:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	20	from	concentrations	251:264	arg1	variations					205:214	the variations	201:214	the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	201:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	9	21	theme	starch	1240:1245	arg1	thickeners					1247:1256	starch thickeners	1240:1256	starch thickeners	1240:1256	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	2	22	theme	compositions	303:314	arg1	time					285:288	time	285:288	time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	285:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	6	23	theme	%	893:893	arg1	maximum					879:885	a maximum	877:885	a maximum of 6.5%	877:893	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	3	24	theme	pudding	522:528	arg1	texture					530:536	pudding texture	522:536	pudding texture	522:536	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	2	25	from	evolution	270:278	arg1	water					232:236	water	232:236	water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	232:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	2	25	from	evolution	270:278	arg1	variations					205:214	the variations	201:214	the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	201:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	0	26	theme	Thickeners	40:49	arg1	Stability					27:35	Stability	27:35	Stability	27:35	Rheological Properties and Stability of Thickeners for Clinical Use.					
36079712	0	26	theme	Thickeners	40:49	arg1	Properties					12:21	Rheological Properties	0:21	Rheological Properties	0:21	Rheological Properties and Stability of Thickeners for Clinical Use.					
36079712	5	27	theme	viscosity	782:790	arg1	changes					792:798	viscosity changes	782:798	viscosity changes	782:798	We analyzed viscosity changes after 6 h of preparation.					
36079712	3	28	dep	thickeners	581:590	arg1	or					599:600	or	599:600	or	599:600	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	3	29	from	concentration	419:431	arg1	water					436:440	water	436:440	water	436:440	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	8	30	theme	thickener	1190:1198	arg1	quantity					1178:1185	less quantity	1173:1185	less quantity of thickener	1173:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	0	31	theme	Clinical	55:62	arg1	Use					64:66	Clinical Use	55:66	Clinical Use	55:66	Rheological Properties and Stability of Thickeners for Clinical Use.					
36079712	9	32	theme	exponential	1266:1276	arg1	behavior					1278:1285	an exponential behavior	1263:1285	an exponential behavior which is difficult to handle, they reach pudding-like viscosity	1263:1349	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	9	32	theme	exponential	1266:1276	arg1	difficult					1296:1304	difficult	1296:1304	difficult	1296:1304	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	8	33	theme	nectar	1137:1142	arg1	textures					1159:1166	nectar and honey-like textures	1137:1166	nectar and honey-like textures	1137:1166	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	2	34	theme	viscosity	219:227	arg1	variations					205:214	the variations	201:214	the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	201:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	3	35	theme	gum-based	460:468	arg1	thickeners					470:479	gum-based thickeners	460:479	gum-based thickeners	460:479	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	2	36	theme	different	241:249	arg1	concentrations					251:264	different concentrations	241:264	different concentrations	241:264	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	8	37	dep	formula	1108:1114	arg1	present					1119:1125	present	1119:1125	present	1119:1125	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	3	38	theme	thickeners	581:590	arg1	viscosity					551:559	the viscosity	547:559	the viscosity of the starch-based thickeners (alone or mixed with gums)	547:617	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	9	39	contain	have	1258:1261	arg1	thickeners					1247:1256	starch thickeners	1240:1256	starch thickeners	1240:1256	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	9	39	contain	have	1258:1261	arg2	behavior					1278:1285	an exponential behavior	1263:1285	an exponential behavior which is difficult to handle, they reach pudding-like viscosity	1263:1349	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	9	39	contain	have	1258:1261	arg2	difficult					1296:1304	difficult	1296:1304	difficult	1296:1304	In contrast, starch thickeners have an exponential behavior which is difficult to handle, they reach pudding-like viscosity, and are not stable over time.					
36079712	4	40	theme	thickeners	721:730	arg1	concentrations					694:707	different concentrations	684:707	different concentrations of the four thickeners using regression analysis (R2 > 0.9)	684:767	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	4	41	theme	regression	738:747	arg1	analysis					749:756	regression analysis	738:756	regression analysis (R2 > 0.9)	738:767	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	4	41	theme	regression	738:747	arg1	>					762:762	R2 > 0.9	759:766	R2 > 0.9	759:766	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	2	42	theme	thickeners	330:339	arg1	compositions					303:314	the three compositions	293:314	the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum)	293:398	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	4	43	theme	R2	759:760	arg1	analysis					749:756	regression analysis	738:756	regression analysis (R2 > 0.9)	738:767	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	4	43	theme	R2	759:760	arg1	>					762:762	R2 > 0.9	759:766	R2 > 0.9	759:766	We modeled the viscosity at different concentrations of the four thickeners using regression analysis (R2 > 0.9).					
36079712	5	44	theme	preparation	813:823	arg1	h					808:808	6 h	806:808	6 h of preparation	806:823	We analyzed viscosity changes after 6 h of preparation.					
36079712	6	45	theme	starch-based	927:938	arg1	thickeners					940:949	starch-based thickeners	927:949	starch-based thickeners	927:949	The viscosity of gum-based thickeners increased by a maximum of 6.5% after 6 h of preparation, while starch-based thickeners increased by up to 43%.					
36079712	8	46	theme	Gum-based	1043:1051	arg1	thickeners					1053:1062	Gum-based thickeners	1043:1062	Gum-based thickeners	1043:1062	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
36079712	2	47	with	starch	373:378	arg1	gums					385:388	gums	385:388	gums	385:388	We describe the variations of viscosity in water at different concentrations and evolution over time of the three compositions of commercial thickeners that are on the market (starch, starch with gums, and gum).					
36079712	3	48	theme	starch-based	568:579	arg1	thickeners					581:590	the starch-based thickeners	564:590	the starch-based thickeners (alone or mixed with gums)	564:617	By increasing the concentration in water, the viscosity of gum-based thickeners increases linearly, but it did not reach pudding texture, whereas the viscosity of the starch-based thickeners (alone or mixed with gums) rapidly reaches very thick textures.					
36079712	8	49	theme	predictable	1071:1081	arg1	behavior					1090:1097	a predictable linear behavior	1069:1097	a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener	1069:1198	Gum-based thickeners have a predictable linear behavior with the formula we present, reaching nectar and honey-like textures with less quantity of thickener, and are stable over time.					
35240217	0	0	theme	porous	88:93	arg1	templates					123:131	templates	123:131	templates	123:131	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	0	0	theme	porous	88:93	arg1	fibers					113:118	porous cellulose acetate fibers	88:118	porous cellulose acetate fibers	88:118	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	1	1	theme	ambient	327:333	arg1	temperatures					335:346	ambient temperatures	327:346	ambient temperatures	327:346	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	2	theme	good	1023:1026	arg1	selectivity					1028:1038	good selectivity	1023:1038	good selectivity to formaldehyde over diverse volatile organic compounds	1023:1094	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	3	3	theme	C-NFMs	730:735	arg1	interconnectivity					686:702	immense pore interconnectivity	673:702	immense pore interconnectivity	673:702	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	3	theme	C-NFMs	730:735	arg1	structure					662:670	the unique heterojunction structure	636:670	the unique heterojunction structure	636:670	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	3	theme	C-NFMs	730:735	arg1	area					722:725	large surface area	708:725	large surface area	708:725	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	4	theme	surface	714:720	arg1	area					722:725	large surface area	708:725	large surface area	708:725	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	4	5	theme	diverse	1061:1067	arg1	compounds					1086:1094	diverse volatile organic compounds	1061:1094	diverse volatile organic compounds	1061:1094	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	3	6	theme	equals	870:875	arg1	26 ppb					827:832	26 ppb	827:832	26 ppb	827:832	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	6	theme	equals	870:875	arg1	limit					840:844	a limit	838:844	a limit of quantification value equals to 87 ppb	838:885	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	0	7	theme	acetate	105:111	arg1	templates					123:131	templates	123:131	templates	123:131	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	0	7	theme	acetate	105:111	arg1	fibers					113:118	porous cellulose acetate fibers	88:118	porous cellulose acetate fibers	88:118	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	5	8	theme	adsorption	1129:1138	arg1	process					1140:1146	the adsorption process	1125:1146	the adsorption process of QCM coated sensors	1125:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	2	9	theme	calcination	599:609	arg1	process					611:617	calcination process	599:617	calcination process	599:617	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	5	10	theme	formaldehyde	1263:1274	arg1	gas					1276:1278	formaldehyde gas	1263:1278	formaldehyde gas	1263:1278	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	5	11	theme	QCM	1151:1153	arg1	sensors					1162:1168	QCM coated sensors	1151:1168	QCM coated sensors	1151:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	0	12	theme	cellulose	95:103	arg1	templates					123:131	templates	123:131	templates	123:131	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	0	12	theme	cellulose	95:103	arg1	fibers					113:118	porous cellulose acetate fibers	88:118	porous cellulose acetate fibers	88:118	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	3	13	theme	as-developed	742:753	arg1	sensors					759:765	the as-developed QCM sensors	738:765	the as-developed QCM sensors	738:765	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	14	theme	low	790:792	arg1	limit					794:798	an extremely low limit	777:798	an extremely low limit of detection (LOD)	777:817	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	2	15	theme	sol-gel	522:528	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	3	16	theme	QCM	755:757	arg1	sensors					759:765	the as-developed QCM sensors	738:765	the as-developed QCM sensors	738:765	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	1	17	theme	CuO/ZnO	177:183	arg1	C-NFMs					213:218	C-NFMs	213:218	C-NFMs	213:218	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	17	theme	CuO/ZnO	177:183	arg1	mats					207:210	CuO/ZnO composite nanofibrous mats	177:210	CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM)	177:260	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	18	theme	response	951:958	arg1	80s					967:969	80s	967:969	80s	967:969	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	4	18	theme	response	951:958	arg1	times					960:964	short response times	945:964	short response times (80s)	945:970	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	4	19	theme	long-term	977:985	arg1	stability					987:995	the long-term stability	973:995	the long-term stability during 3 weeks	973:1010	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	1	20	theme	composite	185:193	arg1	C-NFMs					213:218	C-NFMs	213:218	C-NFMs	213:218	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	20	theme	composite	185:193	arg1	mats					207:210	CuO/ZnO composite nanofibrous mats	177:210	CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM)	177:260	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	0	21	theme	sensitive	7:15	arg1	sensors					30:36	Highly sensitive formaldehyde sensors	0:36	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats	0:80	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	5	22	theme	sorption	1101:1108	arg1	equilibrium					1110:1120	The sorption equilibrium	1097:1120	The sorption equilibrium in the adsorption process of QCM coated sensors	1097:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	5	22	theme	sorption	1101:1108	arg1	met					1179:1181	met	1179:1181	met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs	1179:1289	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	5	23	with	met	1179:1181	arg1	model					1203:1207	the Freundlich model	1188:1207	the Freundlich model	1188:1207	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	4	24	theme	short	945:949	arg1	80s					967:969	80s	967:969	80s	967:969	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	4	24	theme	short	945:949	arg1	times					960:964	short response times	945:964	short response times (80s)	945:970	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	5	25	theme	coated	1155:1160	arg1	sensors					1162:1168	QCM coated sensors	1151:1168	QCM coated sensors	1151:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	1	26	theme	nanofibrous	195:205	arg1	C-NFMs					213:218	C-NFMs	213:218	C-NFMs	213:218	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	26	theme	nanofibrous	195:205	arg1	mats					207:210	CuO/ZnO composite nanofibrous mats	177:210	CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM)	177:260	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	2	27	theme	high	450:453	arg1	126.53 m2 g-1					469:481	126.53 m2 g-1	469:481	126.53 m2 g-1	469:481	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	2	27	theme	high	450:453	arg1	area					463:466	high surface area	450:466	high surface area (126.53 m2 g-1)	450:482	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	5	28	theme	sensors	1162:1168	arg1	process					1140:1146	the adsorption process	1125:1146	the adsorption process of QCM coated sensors	1125:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	3	29	theme	detection	803:811	arg1	limit					794:798	an extremely low limit	777:798	an extremely low limit of detection (LOD)	777:817	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	2	30	theme	/CuAc2/ZnAc2	552:563	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	5	31	from	equilibrium	1110:1120	arg1	process					1140:1146	the adsorption process	1125:1146	the adsorption process of QCM coated sensors	1125:1168	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	2	32	theme	porous	431:436	arg1	C-NFMs					438:443	Triaxial and highly porous C-NFMs	411:443	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1)	411:482	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	0	33	theme	formaldehyde	17:28	arg1	sensors					30:36	Highly sensitive formaldehyde sensors	0:36	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats	0:80	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	4	34	theme	coated	908:913	arg1	sensors					919:925	the C-NFMs coated QCM sensors	897:925	the C-NFMs coated QCM sensors	897:925	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	1	35	from	temperatures	335:346	arg1	determination					290:302	stable determination	283:302	stable determination of formaldehyde gas at ambient temperatures	283:346	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	36	theme	stable	283:288	arg1	determination					290:302	stable determination	283:302	stable determination of formaldehyde gas at ambient temperatures	283:346	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	2	37	theme	CA	549:550	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	3	38	theme	immense	673:679	arg1	interconnectivity					686:702	immense pore interconnectivity	673:702	immense pore interconnectivity	673:702	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	39	from	area	722:725	arg1	Benefiting					620:629	Benefiting	620:629	Benefiting	620:629	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	1	40	theme	determination	290:302	arg1	sensor					161:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	40	theme	determination	290:302	arg1	capable					272:278	capable	272:278	capable	272:278	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	3	41	theme	heterojunction	647:660	arg1	structure					662:670	the unique heterojunction structure	636:670	the unique heterojunction structure	636:670	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	2	42	theme	Triaxial	411:418	arg1	C-NFMs					438:443	Triaxial and highly porous C-NFMs	411:443	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1)	411:482	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	0	43	theme	composite	55:63	arg1	mats					77:80	CuO/ZnO composite nanofibrous mats	47:80	CuO/ZnO composite nanofibrous mats	47:80	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	2	44	theme	acetate	540:546	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	3	45	from	interconnectivity	686:702	arg1	Benefiting					620:629	Benefiting	620:629	Benefiting	620:629	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	2	46	with	C-NFMs	438:443	arg1	126.53 m2 g-1					469:481	126.53 m2 g-1	469:481	126.53 m2 g-1	469:481	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	2	46	with	C-NFMs	438:443	arg1	area					463:466	high surface area	450:466	high surface area (126.53 m2 g-1)	450:482	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	0	47	theme	CuO/ZnO	47:53	arg1	mats					77:80	CuO/ZnO composite nanofibrous mats	47:80	CuO/ZnO composite nanofibrous mats	47:80	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	1	48	theme	formaldehyde	307:318	arg1	gas					320:322	formaldehyde gas	307:322	formaldehyde gas	307:322	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	49	theme	QCM	915:917	arg1	sensors					919:925	the C-NFMs coated QCM sensors	897:925	the C-NFMs coated QCM sensors	897:925	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	3	50	theme	quantification	849:862	arg1	equals					870:875	quantification value equals	849:875	quantification value equals to 87 ppb	849:885	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	1	51	theme	gas	320:322	arg1	determination					290:302	stable determination	283:302	stable determination of formaldehyde gas at ambient temperatures	283:346	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	52	theme	C-NFMs	901:906	arg1	sensors					919:925	the C-NFMs coated QCM sensors	897:925	the C-NFMs coated QCM sensors	897:925	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	3	53	theme	large	708:712	arg1	area					722:725	large surface area	708:725	large surface area	708:725	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	5	54	theme	Freundlich	1192:1201	arg1	model					1203:1207	the Freundlich model	1188:1207	the Freundlich model	1188:1207	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	3	55	theme	value	864:868	arg1	equals					870:875	quantification value equals	849:875	quantification value equals to 87 ppb	849:885	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	1	56	theme	quartz	228:233	arg1	microbalance					243:254	quartz crystal microbalance	228:254	quartz crystal microbalance (QCM)	228:260	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	56	theme	quartz	228:233	arg1	QCM					257:259	QCM	257:259	QCM	257:259	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	2	57	theme	complex	565:571	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	3	58	theme	pore	681:684	arg1	interconnectivity					686:702	immense pore interconnectivity	673:702	immense pore interconnectivity	673:702	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	3	59	theme	unique	640:645	arg1	structure					662:670	the unique heterojunction structure	636:670	the unique heterojunction structure	636:670	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	1	60	theme	innovative	137:146	arg1	sensor					161:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	60	theme	innovative	137:146	arg1	capable					272:278	capable	272:278	capable	272:278	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	61	theme	organic	1078:1084	arg1	compounds					1086:1094	diverse volatile organic compounds	1061:1094	diverse volatile organic compounds	1061:1094	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	1	62	theme	crystal	235:241	arg1	microbalance					243:254	quartz crystal microbalance	228:254	quartz crystal microbalance (QCM)	228:260	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	62	theme	crystal	235:241	arg1	QCM					257:259	QCM	257:259	QCM	257:259	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	63	theme	formaldehyde	148:159	arg1	sensor					161:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor	134:166	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	1	63	theme	formaldehyde	148:159	arg1	capable					272:278	capable	272:278	capable	272:278	An innovative formaldehyde sensor based on CuO/ZnO composite nanofibrous mats (C-NFMs) coated quartz crystal microbalance (QCM), which is capable of stable determination of formaldehyde gas at ambient temperatures sensitively and selectively, has been successfully fabricated.					
35240217	4	64	theme	volatile	1069:1076	arg1	compounds					1086:1094	diverse volatile organic compounds	1061:1094	diverse volatile organic compounds	1061:1094	Besides, the C-NFMs coated QCM sensors also demonstrated short response times (80s), the long-term stability during 3 weeks as well as good selectivity to formaldehyde over diverse volatile organic compounds.					
35240217	0	65	theme	nanofibrous	65:75	arg1	mats					77:80	CuO/ZnO composite nanofibrous mats	47:80	CuO/ZnO composite nanofibrous mats	47:80	Highly sensitive formaldehyde sensors based on CuO/ZnO composite nanofibrous mats using porous cellulose acetate fibers as templates.					
35240217	3	66	from	structure	662:670	arg1	Benefiting					620:629	Benefiting	620:629	Benefiting	620:629	Benefiting from the unique heterojunction structure, immense pore interconnectivity and large surface area of C-NFMs, the as-developed QCM sensors exhibited an extremely low limit of detection (LOD) down to 26 ppb and a limit of quantification value equals to 87 ppb.					
35240217	2	67	theme	surface	455:461	arg1	126.53 m2 g-1					469:481	126.53 m2 g-1	469:481	126.53 m2 g-1	469:481	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	2	67	theme	surface	455:461	arg1	area					463:466	high surface area	450:466	high surface area (126.53 m2 g-1)	450:482	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35240217	5	68	theme	heterogeneous	1230:1242	arg1	adsorption					1244:1253	the heterogeneous adsorption	1226:1253	the heterogeneous adsorption between formaldehyde gas and C-NFMs	1226:1289	The sorption equilibrium in the adsorption process of QCM coated sensors was well met with the Freundlich model, which certified the heterogeneous adsorption between formaldehyde gas and C-NFMs.					
35240217	2	69	theme	cellulose	530:538	arg1	solution					573:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution	520:580	Triaxial and highly porous C-NFMs with high surface area (126.53 m2 g-1) were synthesized by electrospinning a sol-gel cellulose acetate (CA)/CuAc2/ZnAc2 complex solution and following by calcination process.					
35626690	0	0	theme	Murine	103:108	arg1	Model					129:133	a Murine Cardiac Transplant Model	101:133	a Murine Cardiac Transplant Model	101:133	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	4	1	theme	Cardiac	534:540	arg1	grafts					542:547	Cardiac grafts	534:547	Cardiac grafts	534:547	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	9	2	theme	preservative	1416:1427	arg1	capacity					1429:1436	an improved preservative capacity	1404:1436	an improved preservative capacity	1404:1436	Unisol-based solutions showed an improved preservative capacity compared with the gold standard HTK early after cardiac transplantation.					
35626690	6	3	theme	Glut	892:895	arg1	s					900:900	Glut 47 s	892:900	Glut 47 s	892:900	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	7	4	theme	increased	1056:1064	arg1	recruitment					1076:1086	a significantly increased leukocyte recruitment	1040:1086	a significantly increased leukocyte recruitment	1040:1086	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	1	5	theme	easiest	176:182	arg1	storage					148:154	Static cold storage	136:154	Static cold storage	136:154	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	1	5	theme	easiest	176:182	arg1	method					184:189	the cheapest and easiest method	159:189	the cheapest and easiest method	159:189	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	0	6	theme	Transplant	118:127	arg1	Model					129:133	a Murine Cardiac Transplant Model	101:133	a Murine Cardiac Transplant Model	101:133	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	5	7	theme	Cardiac	671:677	arg1	grafts					679:684	Cardiac grafts	671:684	Cardiac grafts	671:684	Cardiac grafts were assessed for rebeating and functionality, histomorphologic alterations, and cytokine expression.					
35626690	6	8	theme	UHK	849:851	arg1	s					856:856	UHK 56 s	849:856	UHK 56 s	849:856	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	8	9	theme	UHK-	1250:1253	arg1	animals					1271:1277	UHK- and ULK-treated animals	1250:1277	UHK- and ULK-treated animals	1250:1277	In UHK- and ULK-treated animals, a trend toward decreased expression of proinflammatory markers was seen when compared to HTK.					
35626690	8	10	theme	decreased	1295:1303	arg1	expression					1305:1314	decreased expression	1295:1314	decreased expression of proinflammatory markers	1295:1341	In UHK- and ULK-treated animals, a trend toward decreased expression of proinflammatory markers was seen when compared to HTK.					
35626690	0	11	theme	Cardiac	110:116	arg1	Model					129:133	a Murine Cardiac Transplant Model	101:133	a Murine Cardiac Transplant Model	101:133	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	4	12	dep	high-	613:617	arg1	UHK					619:621	UHK	619:621	UHK	619:621	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	10	13	theme	tissue-protective	1560:1576	arg1	properties					1578:1587	tissue-protective properties	1560:1587	tissue-protective properties	1560:1587	Supplemented glutathione did not further improve tissue-protective properties.					
35626690	2	14	theme	preservative	285:296	arg1	capacity					298:305	the preservative capacity	281:305	the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution	281:411	This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution.					
35626690	7	15	theme	cells	1198:1202	arg1	number					1178:1183	the number	1174:1183	the number of apoptotic cells	1174:1202	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	7	15	theme	cells	1198:1202	arg1	lower					1217:1221	lower	1217:1221	lower	1217:1221	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	7	16	theme	damage	1120:1125	arg1	degrees					1102:1108	similar degrees	1094:1108	similar degrees of tissue damage and inflammatory infiltrate in all groups	1094:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	2	17	theme	histidine-tryptophan-ketoglutarate	363:396	arg1	solution					404:411	histidine-tryptophan-ketoglutarate (HTK) solution	363:411	histidine-tryptophan-ketoglutarate (HTK) solution	363:411	This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution.					
35626690	9	18	theme	Unisol-based	1374:1385	arg1	solutions					1387:1395	Unisol-based solutions	1374:1395	Unisol-based solutions	1374:1395	Unisol-based solutions showed an improved preservative capacity compared with the gold standard HTK early after cardiac transplantation.					
35626690	4	19	with	solutions	598:606	arg1	glutathione					650:660	glutathione	650:660	glutathione	650:660	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	4	19	with	solutions	598:606	arg1	HTK					666:668	HTK	666:668	HTK	666:668	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	5	20	theme	cytokine	767:774	arg1	expression					776:785	cytokine expression	767:785	cytokine expression	767:785	Cardiac grafts were assessed for rebeating and functionality, histomorphologic alterations, and cytokine expression.					
35626690	6	21	theme	rebeating	833:841	arg1	time					843:846	a faster rebeating time	824:846	a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s)	824:901	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	3	22	theme	heterotopic	431:441	arg1	transplantations					449:464	Murine syngeneic heterotopic heart transplantations	414:464	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c)	414:480	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	3	22	theme	heterotopic	431:441	arg1	Balb/c-Balb/c					467:479	Balb/c-Balb/c	467:479	Balb/c-Balb/c	467:479	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	6	23	dep	rebeating	833:841	arg1	faster					826:831	faster	826:831	faster	826:831	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	0	24	theme	Perfusion	31:39	arg1	Solutions					41:49	Gluconate-Lactobionate-Dextran Perfusion Solutions	0:49	Gluconate-Lactobionate-Dextran Perfusion Solutions	0:49	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	6	25	theme	ULK	876:878	arg1	s					883:883	ULK 45 s	876:883	ULK 45 s	876:883	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	2	26	theme	Unisol	342:347	arg1	solutions					350:358	gluconate-lactobionate-dextran (Unisol) solutions	310:358	gluconate-lactobionate-dextran (Unisol) solutions	310:358	This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution.					
35626690	7	27	from	degrees	1102:1108	arg1	groups					1162:1167	all groups	1158:1167	all groups	1158:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	0	28	theme	Gluconate-Lactobionate-Dextran	0:29	arg1	Solutions					41:49	Gluconate-Lactobionate-Dextran Perfusion Solutions	0:49	Gluconate-Lactobionate-Dextran Perfusion Solutions	0:49	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	9	29	theme	cardiac	1486:1492	arg1	transplantation					1494:1508	cardiac transplantation	1486:1508	cardiac transplantation	1486:1508	Unisol-based solutions showed an improved preservative capacity compared with the gold standard HTK early after cardiac transplantation.					
35626690	7	30	theme	Ischemic	1017:1024	arg1	injury					1026:1031	Ischemic injury	1017:1031	Ischemic injury	1017:1031	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	7	31	theme	similar	1094:1100	arg1	degrees					1102:1108	similar degrees	1094:1108	similar degrees of tissue damage and inflammatory infiltrate in all groups	1094:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	4	32	theme	Unisol-based	585:596	arg1	solutions					598:606	Unisol-based solutions	585:606	Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK	585:668	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	2	33	theme	gluconate-lactobionate-dextran	310:339	arg1	solutions					350:358	gluconate-lactobionate-dextran (Unisol) solutions	310:358	gluconate-lactobionate-dextran (Unisol) solutions	310:358	This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution.					
35626690	6	34	dep	time	843:846	arg1	s					883:883	ULK 45 s	876:883	ULK 45 s	876:883	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	6	34	dep	time	843:846	arg1	s					856:856	UHK 56 s	849:856	UHK 56 s	849:856	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	6	34	dep	time	843:846	arg1	s					873:873	UHK + Glut 44 s	859:873	s	873:873	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	6	34	dep	time	843:846	arg1	s					900:900	Glut 47 s	892:900	Glut 47 s	892:900	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	6	34	dep	time	843:846	arg1	ULK					886:888	ULK	886:888	ULK	886:888	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	3	35	theme	Murine	414:419	arg1	transplantations					449:464	Murine syngeneic heterotopic heart transplantations	414:464	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c)	414:480	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	3	35	theme	Murine	414:419	arg1	Balb/c-Balb/c					467:479	Balb/c-Balb/c	467:479	Balb/c-Balb/c	467:479	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	4	36	theme	high-	613:617	arg1	glutathione					650:660	glutathione	650:660	glutathione	650:660	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	8	37	theme	ULK-treated	1259:1269	arg1	animals					1271:1277	UHK- and ULK-treated animals	1250:1277	UHK- and ULK-treated animals	1250:1277	In UHK- and ULK-treated animals, a trend toward decreased expression of proinflammatory markers was seen when compared to HTK.					
35626690	7	38	from	damage	1120:1125	arg1	groups					1162:1167	all groups	1158:1167	all groups	1158:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	4	39	theme	±	648:648	arg1	glutathione					650:660	glutathione	650:660	glutathione	650:660	Cardiac grafts were either flushed and stored with Unisol-based solutions with high-(UHK) and low-potassium (ULK) ± glutathione, or HTK.					
35626690	9	40	theme	improved	1407:1414	arg1	capacity					1429:1436	an improved preservative capacity	1404:1436	an improved preservative capacity	1404:1436	Unisol-based solutions showed an improved preservative capacity compared with the gold standard HTK early after cardiac transplantation.					
35626690	7	41	theme	tissue	1113:1118	arg1	damage					1120:1125	tissue damage	1113:1125	tissue damage	1113:1125	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	7	42	from	infiltrate	1144:1153	arg1	groups					1162:1167	all groups	1158:1167	all groups	1158:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	0	43	theme	Ischemic	61:68	arg1	Injury					70:75	Ischemic Injury	61:75	Ischemic Injury	61:75	Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.					
35626690	5	44	theme	histomorphologic	733:748	arg1	alterations					750:760	histomorphologic alterations	733:760	histomorphologic alterations	733:760	Cardiac grafts were assessed for rebeating and functionality, histomorphologic alterations, and cytokine expression.					
35626690	3	45	theme	heart	443:447	arg1	transplantations					449:464	Murine syngeneic heterotopic heart transplantations	414:464	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c)	414:480	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	3	45	theme	heart	443:447	arg1	Balb/c-Balb/c					467:479	Balb/c-Balb/c	467:479	Balb/c-Balb/c	467:479	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	7	46	theme	inflammatory	1131:1142	arg1	infiltrate					1144:1153	inflammatory infiltrate	1131:1153	inflammatory infiltrate	1131:1153	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	10	47	theme	Supplemented	1511:1522	arg1	glutathione					1524:1534	Supplemented glutathione	1511:1534	Supplemented glutathione	1511:1534	Supplemented glutathione did not further improve tissue-protective properties.					
35626690	6	48	theme	Glut	865:868	arg1	s					873:873	UHK + Glut 44 s	859:873	s	873:873	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	6	49	theme	Unisol-based	788:799	arg1	solutions					801:809	Unisol-based solutions	788:809	Unisol-based solutions	788:809	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	3	50	theme	storage	525:531	arg1	h					508:508	18 h	505:508	18 h of static cold storage	505:531	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	1	51	theme	Static	136:141	arg1	storage					148:154	Static cold storage	136:154	Static cold storage	136:154	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	1	51	theme	Static	136:141	arg1	method					184:189	the cheapest and easiest method	159:189	the cheapest and easiest method	159:189	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	3	52	theme	static	513:518	arg1	storage					525:531	static cold storage	513:531	static cold storage	513:531	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	9	53	theme	standard	1461:1468	arg1	HTK					1470:1472	the gold standard HTK	1452:1472	the gold standard HTK	1452:1472	Unisol-based solutions showed an improved preservative capacity compared with the gold standard HTK early after cardiac transplantation.					
35626690	1	54	theme	cheapest	163:170	arg1	storage					148:154	Static cold storage	136:154	Static cold storage	136:154	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	1	54	theme	cheapest	163:170	arg1	method					184:189	the cheapest and easiest method	159:189	the cheapest and easiest method	159:189	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	7	55	theme	infiltrate	1144:1153	arg1	degrees					1102:1108	similar degrees	1094:1108	similar degrees of tissue damage and inflammatory infiltrate in all groups	1094:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	1	56	theme	cold	143:146	arg1	storage					148:154	Static cold storage	136:154	Static cold storage	136:154	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	1	56	theme	cold	143:146	arg1	method					184:189	the cheapest and easiest method	159:189	the cheapest and easiest method	159:189	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	6	57	theme	UHK	859:861	arg1	s					873:873	UHK + Glut 44 s	859:873	s	873:873	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	8	58	theme	markers	1335:1341	arg1	expression					1305:1314	decreased expression	1295:1314	decreased expression of proinflammatory markers	1295:1341	In UHK- and ULK-treated animals, a trend toward decreased expression of proinflammatory markers was seen when compared to HTK.					
35626690	6	59	from	endpoint	998:1005	arg1	POD					1010:1012	POD 3	1010:1014	POD 3	1010:1014	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	2	60	theme	solutions	350:358	arg1	capacity					298:305	the preservative capacity	281:305	the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution	281:411	This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan-ketoglutarate (HTK) solution.					
35626690	7	61	from	groups	1162:1167	arg1	degrees					1102:1108	similar degrees	1094:1108	similar degrees of tissue damage and inflammatory infiltrate in all groups	1094:1167	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	8	62	theme	proinflammatory	1319:1333	arg1	markers					1335:1341	proinflammatory markers	1319:1341	proinflammatory markers	1319:1341	In UHK- and ULK-treated animals, a trend toward decreased expression of proinflammatory markers was seen when compared to HTK.					
35626690	3	63	theme	cold	520:523	arg1	storage					525:531	static cold storage	513:531	static cold storage	513:531	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	1	64	theme	donor	239:243	arg1	organs					245:250	donor organs	239:250	donor organs	239:250	Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs.					
35626690	7	65	theme	leukocyte	1066:1074	arg1	recruitment					1076:1086	a significantly increased leukocyte recruitment	1040:1086	a significantly increased leukocyte recruitment	1040:1086	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	6	66	dep	along	929:933	arg1	with					935:938	with	935:938	with	935:938	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
35626690	7	67	theme	apoptotic	1188:1196	arg1	cells					1198:1202	apoptotic cells	1188:1202	apoptotic cells	1188:1202	Ischemic injury led to a significantly increased leukocyte recruitment, with similar degrees of tissue damage and inflammatory infiltrate in all groups, yet the number of apoptotic cells tended to be lower in ULK compared to HTK.					
35626690	3	68	theme	syngeneic	421:429	arg1	transplantations					449:464	Murine syngeneic heterotopic heart transplantations	414:464	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c)	414:480	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	3	68	theme	syngeneic	421:429	arg1	Balb/c-Balb/c					467:479	Balb/c-Balb/c	467:479	Balb/c-Balb/c	467:479	Murine syngeneic heterotopic heart transplantations (Balb/c-Balb/c) were carried out after 18 h of static cold storage.					
35626690	6	69	theme	better	942:947	arg1	contractility					949:961	a better contractility	940:961	HTK (119.5 s) along with a better contractility	915:961	Unisol-based solutions demonstrated a faster rebeating time (UHK 56 s, UHK + Glut 44 s, ULK 45 s, ULK + Glut 47 s) compared to HTK (119.5 s) along with a better contractility early after reperfusion and at the endpoint on POD 3.					
36087961	7	0	theme	acid-base	1014:1022	arg1	resistance					1024:1033	excellent acid-base resistance	1004:1033	excellent acid-base resistance (suitable pH 2-12)	1004:1052	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	0	theme	acid-base	1014:1022	arg1	pH 2-12					1045:1051	suitable pH 2-12	1036:1051	suitable pH 2-12	1036:1051	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	3	1	from	elements	442:449	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	1	from	elements	442:449	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	1	from	elements	442:449	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	1	2	theme	chitosan	232:239	arg1	stability					219:227	poor stability	214:227	poor stability	214:227	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	1	2	theme	chitosan	232:239	arg1	strength					174:181	low mechanical strength	159:181	low mechanical strength	159:181	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	1	2	theme	chitosan	232:239	arg1	efficiency					199:208	low adsorption efficiency	184:208	low adsorption efficiency	184:208	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	5	3	theme	adsorbed	774:781	arg1	Cr					783:784	the adsorbed Cr	770:784	the adsorbed Cr	770:784	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	3	4	theme	EDS	484:486	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	4	5	dep	includes	604:611	arg1	VI					574:575	VI	574:575	VI	574:575	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	3	6	theme	SEM-mapping	468:478	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	7	theme	XPS	454:456	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	1	8	dep	strategy	125:132	arg1	solve					137:141	solve	137:141	to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan	134:239	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	6	9	from	298 K	965:969	arg1	246.72 mg g-1					948:960	246.72 mg g-1	948:960	246.72 mg g-1	948:960	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	6	9	from	298 K	965:969	arg1	capacity					918:925	The maximum adsorption capacity	895:925	The maximum adsorption capacity of CS-thiourea-Zr	895:943	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	3	10	theme	bonds	409:413	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	0	11	from	detoxification	60:73	arg1	solution					101:108	aqueous solution	93:108	aqueous solution	93:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	5	12	dep	Cr	695:696	arg1	VI					698:699	VI	698:699	VI	698:699	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	5	13	theme	electrostatic	717:729	arg1	adsorption					731:740	electrostatic adsorption	717:740	electrostatic adsorption	717:740	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	3	14	theme	S	440:440	arg1	elements					442:449	S elements	440:449	S elements in XPS spectrum	440:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	2	15	theme	first	359:363	arg1	time					365:368	the first time	355:368	the first time	355:368	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	4	16	theme	Cr	571:572	arg1	mechanism					558:566	The main mechanism	549:566	The main mechanism of Cr	549:572	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	0	17	theme	aqueous	93:99	arg1	solution					101:108	aqueous solution	93:108	aqueous solution	93:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	6	18	theme	maximum	899:905	arg1	246.72 mg g-1					948:960	246.72 mg g-1	948:960	246.72 mg g-1	948:960	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	6	18	theme	maximum	899:905	arg1	capacity					918:925	The maximum adsorption capacity	895:925	The maximum adsorption capacity of CS-thiourea-Zr	895:943	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	3	19	theme	elements	442:449	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	6	20	from	pH = 2.0	975:982	arg1	246.72 mg g-1					948:960	246.72 mg g-1	948:960	246.72 mg g-1	948:960	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	6	20	from	pH = 2.0	975:982	arg1	capacity					918:925	The maximum adsorption capacity	895:925	The maximum adsorption capacity of CS-thiourea-Zr	895:943	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	1	21	theme	low	159:161	arg1	strength					174:181	low mechanical strength	159:181	low mechanical strength	159:181	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	3	22	from	bonds	409:413	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	22	from	bonds	409:413	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	22	from	bonds	409:413	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	2	23	theme	cross-linked	277:288	arg1	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	5	24	theme	CS	886:887	arg1	bond					889:892	CS bond	886:892	CS bond	886:892	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	1	25	theme	mechanical	163:172	arg1	strength					174:181	low mechanical strength	159:181	low mechanical strength	159:181	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	2	26	theme	Zr4+	272:275	arg1	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	3	27	from	EDS	484:486	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	27	from	EDS	484:486	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	27	from	EDS	484:486	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	1	28	theme	strength	174:181	arg1	problems					147:154	the problems	143:154	the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan	143:239	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	4	29	theme	ion	635:637	arg1	action					627:632	electrostatic action	613:632	electrostatic action	613:632	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	4	29	theme	ion	635:637	arg1	exchange					639:646	ion exchange	635:646	ion exchange	635:646	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	5	30	dep	reduced	793:799	arg1	VI					786:787	VI	786:787	VI	786:787	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	3	31	theme	ZrO	401:403	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	0	32	theme	chitosan-thiourea	18:34	arg1	composite					36:44	chitosan-thiourea composite	18:44	chitosan-thiourea composite	18:44	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	3	33	from	CS	397:398	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	33	from	CS	397:398	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	33	from	CS	397:398	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	0	34	dep	Cr	78:79	arg1	VI					81:82	VI	81:82	VI	81:82	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	0	34	dep	Cr	78:79	arg1	ions					85:88	ions	85:88	Cr(VI) ions in aqueous solution	78:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	1	35	theme	low	184:186	arg1	efficiency					199:208	low adsorption efficiency	184:208	low adsorption efficiency	184:208	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	0	36	theme	efficient	50:58	arg1	detoxification					60:73	efficient detoxification	50:73	efficient detoxification of Cr(VI) ions in aqueous solution	50:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	3	37	theme	FTIR	418:421	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	38	theme	CS	397:398	arg1	results					488:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results	397:494	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	1	39	theme	adsorption	188:197	arg1	efficiency					199:208	low adsorption efficiency	184:208	low adsorption efficiency	184:208	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	5	40	theme	ion	746:748	arg1	exchange					750:757	ion exchange	746:757	ion exchange	746:757	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	5	41	theme	COO-	871:874	arg1	group					876:880	COO- group	871:880	COO- group	871:880	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	2	42	used	used	374:377	arg2	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	1	43	theme	efficiency	199:208	arg1	problems					147:154	the problems	143:154	the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan	143:239	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	5	44	theme	Cr	695:696	arg1	adsorption					681:690	The adsorption	677:690	The adsorption of Cr(VI)	677:700	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	0	45	from	Cr	78:79	arg1	solution					101:108	aqueous solution	93:108	aqueous solution	93:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	2	46	dep	Cr	389:390	arg1	VI					392:393	VI	392:393	VI	392:393	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	6	47	theme	adsorption	907:916	arg1	246.72 mg g-1					948:960	246.72 mg g-1	948:960	246.72 mg g-1	948:960	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	6	47	theme	adsorption	907:916	arg1	capacity					918:925	The maximum adsorption capacity	895:925	The maximum adsorption capacity of CS-thiourea-Zr	895:943	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	4	48	theme	electrostatic	613:625	arg1	complexation					663:674	complexation	663:674	complexation	663:674	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	4	48	theme	electrostatic	613:625	arg1	reduction					649:657	reduction	649:657	reduction	649:657	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	4	48	theme	electrostatic	613:625	arg1	action					627:632	electrostatic action	613:632	electrostatic action	613:632	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	4	48	theme	electrostatic	613:625	arg1	exchange					639:646	ion exchange	635:646	ion exchange	635:646	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	2	49	link	cross-linked	277:288	arg1	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	3	50	theme	CN	406:407	arg1	bonds					409:413	CN bonds	406:413	CN bonds in FTIR spectrum and Zr	406:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	0	51	from	solution	101:108	arg1	detoxification					60:73	efficient detoxification	50:73	efficient detoxification of Cr(VI) ions in aqueous solution	50:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	5	52	theme	Cr	848:849	arg1	adsorption					834:843	the adsorption	830:843	the adsorption of Cr(III)	830:854	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	3	53	from	ZrO	401:403	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	53	from	ZrO	401:403	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	53	from	ZrO	401:403	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	2	54	theme	CS-thiourea-Zr	309:322	arg1	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	5	55	theme	-OH	815:817	arg1	group					819:823	-OH group	815:823	-OH group	815:823	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	7	56	contain	has	1000:1002	arg2	pH 2-12					1045:1051	suitable pH 2-12	1036:1051	suitable pH 2-12	1036:1051	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	56	contain	has	1000:1002	arg2	resistance					1024:1033	excellent acid-base resistance	1004:1033	excellent acid-base resistance (suitable pH 2-12)	1004:1052	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	56	contain	has	1000:1002	arg2	reusability					1058:1068	reusability	1058:1068	reusability	1058:1068	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	56	contain	has	1000:1002	arg1	CS-thiourea-Zr					985:998	CS-thiourea-Zr	985:998	CS-thiourea-Zr	985:998	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	1	57	theme	effective	115:123	arg1	strategy					125:132	The effective strategy	111:132	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan	111:239	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	6	58	theme	CS-thiourea-Zr	930:943	arg1	246.72 mg g-1					948:960	246.72 mg g-1	948:960	246.72 mg g-1	948:960	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	6	58	theme	CS-thiourea-Zr	930:943	arg1	capacity					918:925	The maximum adsorption capacity	895:925	The maximum adsorption capacity of CS-thiourea-Zr	895:943	The maximum adsorption capacity of CS-thiourea-Zr is 246.72 mg g-1 at 298 K and pH = 2.0.					
36087961	5	59	theme	Cr	783:784	arg1	%					765:765	80.6 %	760:765	80.6 % of the adsorbed Cr	760:784	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	5	59	theme	Cr	783:784	arg1	Cr					783:784	the adsorbed Cr	770:784	the adsorbed Cr	770:784	The adsorption of Cr(VI) is enhanced by electrostatic adsorption and ion exchange, 80.6 % of the adsorbed Cr(VI) is reduced to Cr(III) by -OH group, and the adsorption of Cr(III) is enhanced by COO- group and CS bond.					
36087961	3	60	theme	CS-thiourea-Zr	533:546	arg1	preparation					518:528	the successful preparation	503:528	the successful preparation of CS-thiourea-Zr	503:546	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	2	61	theme	chitosan-thiourea	290:306	arg1	composite					325:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite	272:333	In this work, Zr4+ cross-linked chitosan-thiourea (CS-thiourea-Zr) composite was synthesized for the first time and used to remove Cr(VI).					
36087961	3	62	from	SEM-mapping	468:478	arg1	Zr					436:437	Zr	436:437	Zr	436:437	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	62	from	SEM-mapping	468:478	arg1	spectrum					423:430	FTIR spectrum	418:430	FTIR spectrum	418:430	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	3	62	from	SEM-mapping	468:478	arg1	spectrum					458:465	XPS spectrum	454:465	XPS spectrum	454:465	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	1	63	theme	poor	214:217	arg1	stability					219:227	poor stability	214:227	poor stability	214:227	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	4	64	theme	main	553:556	arg1	mechanism					558:566	The main mechanism	549:566	The main mechanism of Cr	549:572	The main mechanism of Cr(VI) removal by CS-thiourea-Zr includes electrostatic action, ion exchange, reduction and complexation.					
36087961	3	65	theme	successful	507:516	arg1	preparation					518:528	the successful preparation	503:528	the successful preparation of CS-thiourea-Zr	503:546	CS, ZrO, CN bonds in FTIR spectrum and Zr, S elements in XPS spectrum, SEM-mapping and EDS results verify the successful preparation of CS-thiourea-Zr.					
36087961	7	66	theme	suitable	1036:1043	arg1	resistance					1024:1033	excellent acid-base resistance	1004:1033	excellent acid-base resistance (suitable pH 2-12)	1004:1052	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	66	theme	suitable	1036:1043	arg1	pH 2-12					1045:1051	suitable pH 2-12	1036:1051	suitable pH 2-12	1036:1051	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	1	67	theme	stability	219:227	arg1	problems					147:154	the problems	143:154	the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan	143:239	The effective strategy to solve the problems of low mechanical strength, low adsorption efficiency and poor stability of chitosan is to modify it.					
36087961	0	68	theme	Cr	78:79	arg1	detoxification					60:73	efficient detoxification	50:73	efficient detoxification of Cr(VI) ions in aqueous solution	50:108	Zr4+ cross-linked chitosan-thiourea composite for efficient detoxification of Cr(VI) ions in aqueous solution.					
36087961	7	69	theme	excellent	1004:1012	arg1	resistance					1024:1033	excellent acid-base resistance	1004:1033	excellent acid-base resistance (suitable pH 2-12)	1004:1052	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
36087961	7	69	theme	excellent	1004:1012	arg1	pH 2-12					1045:1051	suitable pH 2-12	1036:1051	suitable pH 2-12	1036:1051	CS-thiourea-Zr has excellent acid-base resistance (suitable pH 2-12) and reusability.					
37028863	0	0	theme	inactivation	89:100	arg1	technology					102:111	photodynamic inactivation technology	76:111	photodynamic inactivation technology for antibacterial food packaging	76:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	4	1	theme	CFU/mL	899:904	arg1	reductions					851:860	reductions	851:860	reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli	851:951	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	1	2	theme	food	172:175	arg1	quality					177:183	food quality	172:183	food quality	172:183	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	4	3	theme	abundant	786:793	arg1	species					811:817	abundant reactive oxygen species	786:817	abundant reactive oxygen species	786:817	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	1	4	theme	new	249:251	arg1	materials					263:271	new packaging materials	249:271	new packaging materials with antimicrobial activity	249:299	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	0	5	theme	photodynamic	76:87	arg1	technology					102:111	photodynamic inactivation technology	76:111	photodynamic inactivation technology for antibacterial food packaging	76:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	2	6	theme	bactericidal	358:369	arg1	technology					371:380	bactericidal technology	358:380	bactericidal technology	358:380	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	1	7	theme	packaging	253:261	arg1	materials					263:271	new packaging materials	249:271	new packaging materials with antimicrobial activity	249:299	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	5	8	theme	growth	1055:1060	arg1	inhibition					1037:1046	inhibition	1037:1046	inhibition of the growth of colonization	1037:1076	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	6	9	theme	safe	1183:1186	arg1	packaging					1221:1229	safe and efficient antimicrobial food packaging	1183:1229	safe and efficient antimicrobial food packaging	1183:1229	This work will provide new insights to explore safe and efficient antimicrobial food packaging.					
37028863	4	10	with	irradiation	707:717	arg1	source					739:744	a 405 nm light source	724:744	a 405 nm light source	724:744	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	2	11	theme	technology	371:380	arg1	inactivation					342:353	photodynamic inactivation	329:353	photodynamic inactivation of bactericidal technology in food packaging materials	329:408	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	4	12	theme	405 nm	726:731	arg1	source					739:744	a 405 nm light source	724:744	a 405 nm light source	724:744	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	0	13	theme	food	131:134	arg1	packaging					136:144	antibacterial food packaging	117:144	antibacterial food packaging	117:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	2	14	theme	quantum	446:452	arg1	CDs					460:462	CDs	460:462	CDs	460:462	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	14	theme	quantum	446:452	arg1	dots					454:457	fluorescent carbon quantum dots	427:457	fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric	427:504	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	5	15	theme	cold	984:987	arg1	applications					1002:1013	cold pork storage applications	984:1013	cold pork storage applications	984:1013	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	0	16	theme	antibacterial	117:129	arg1	packaging					136:144	antibacterial food packaging	117:144	antibacterial food packaging	117:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	2	17	theme	plant	491:495	arg1	turmeric					497:504	the natural plant turmeric	479:504	the natural plant turmeric	479:504	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	5	18	theme	pork	989:992	arg1	applications					1002:1013	cold pork storage applications	984:1013	cold pork storage applications	984:1013	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	0	19	theme	carbon	9:14	arg1	dots					24:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	5	20	theme	pork	1115:1118	arg1	spoilage					1103:1110	the spoilage	1099:1110	the spoilage of pork	1099:1118	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	6	21	theme	new	1159:1161	arg1	insights					1163:1170	new insights	1159:1170	new insights	1159:1170	This work will provide new insights to explore safe and efficient antimicrobial food packaging.					
37028863	0	22	theme	Turmeric	0:7	arg1	dots					24:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	1	23	theme	antimicrobial	278:290	arg1	activity					292:299	antimicrobial activity	278:299	antimicrobial activity	278:299	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	5	24	theme	colonization	1065:1076	arg1	growth					1055:1060	the growth	1051:1060	the growth of colonization	1051:1076	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	2	25	theme	packaging	390:398	arg1	materials					400:408	food packaging materials	385:408	food packaging materials	385:408	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	4	26	theme	oxygen	804:809	arg1	species					811:817	abundant reactive oxygen species	786:817	abundant reactive oxygen species	786:817	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	2	27	theme	composite	559:567	arg1	CDs-CS					591:596	CDs-CS	591:596	CDs-CS	591:596	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	27	theme	composite	559:567	arg1	films					584:588	active composite food packaging films	552:588	active composite food packaging films (CDs-CS)	552:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	28	from	inactivation	342:353	arg1	materials					400:408	food packaging materials	385:408	food packaging materials	385:408	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	4	29	theme	composite	751:759	arg1	able					770:773	able	770:773	able	770:773	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	4	29	theme	composite	751:759	arg1	film					761:764	the composite film	747:764	the composite film	747:764	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	0	30	theme	quantum	16:22	arg1	dots					24:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots	0:27	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	2	31	theme	active	552:557	arg1	CDs-CS					591:596	CDs-CS	591:596	CDs-CS	591:596	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	31	theme	active	552:557	arg1	films					584:588	active composite food packaging films	552:588	active composite food packaging films (CDs-CS)	552:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	3	32	theme	mechanical	644:653	arg1	hydrophobicity					685:698	hydrophobicity	685:698	hydrophobicity	685:698	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	32	theme	mechanical	644:653	arg1	properties					655:664	better mechanical properties	637:664	better mechanical properties	637:664	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	32	theme	mechanical	644:653	arg1	protection					670:679	UV protection	667:679	UV protection	667:679	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	6	33	theme	efficient	1192:1200	arg1	packaging					1221:1229	safe and efficient antimicrobial food packaging	1183:1229	safe and efficient antimicrobial food packaging	1183:1229	This work will provide new insights to explore safe and efficient antimicrobial food packaging.					
37028863	1	34	theme	food	208:211	arg1	industry					213:220	the food industry	204:220	the food industry	204:220	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	0	35	theme	chitosan	38:45	arg1	films					61:65	chitosan nanocomposite films	38:65	chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging	38:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	5	36	theme	CDs-CS2	1016:1022	arg1	films					1024:1028	CDs-CS2 films	1016:1028	CDs-CS2 films	1016:1028	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	2	37	theme	carbon	439:444	arg1	CDs					460:462	CDs	460:462	CDs	460:462	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	37	theme	carbon	439:444	arg1	dots					454:457	fluorescent carbon quantum dots	427:457	fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric	427:504	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	38	theme	natural	483:489	arg1	turmeric					497:504	the natural plant turmeric	479:504	the natural plant turmeric	479:504	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	1	39	with	materials	263:271	arg1	activity					292:299	antimicrobial activity	278:299	antimicrobial activity	278:299	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	2	40	theme	fluorescent	427:437	arg1	CDs					460:462	CDs	460:462	CDs	460:462	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	40	theme	fluorescent	427:437	arg1	dots					454:457	fluorescent carbon quantum dots	427:457	fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric	427:504	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	4	41	theme	Log10	893:897	arg1	CFU/mL					899:904	approximately 3.19 and 2.05 Log10 CFU/mL	865:904	approximately 3.19 and 2.05 Log10 CFU/mL	865:904	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	3	42	theme	better	637:642	arg1	hydrophobicity					685:698	hydrophobicity	685:698	hydrophobicity	685:698	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	42	theme	better	637:642	arg1	properties					655:664	better mechanical properties	637:664	better mechanical properties	637:664	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	42	theme	better	637:642	arg1	protection					670:679	UV protection	667:679	UV protection	667:679	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	0	43	theme	nanocomposite	47:59	arg1	films					61:65	chitosan nanocomposite films	38:65	chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging	38:144	Turmeric carbon quantum dots enhanced chitosan nanocomposite films based on photodynamic inactivation technology for antibacterial food packaging.					
37028863	2	44	theme	films	584:588	arg1	series					542:547	a series	540:547	a series of active composite food packaging films (CDs-CS)	540:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	4	45	theme	CDs-CS2	828:834	arg1	film					836:839	the CDs-CS2 film	824:839	the CDs-CS2 film	824:839	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	4	46	theme	light	733:737	arg1	source					739:744	a 405 nm light source	724:744	a 405 nm light source	724:744	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	4	47	theme	reactive	795:802	arg1	species					811:817	abundant reactive oxygen species	786:817	abundant reactive oxygen species	786:817	Under irradiation with a 405 nm light source, the composite film was able to produce abundant reactive oxygen species, and the CDs-CS2 film exhibited reductions of approximately 3.19 and 2.05 Log10 CFU/mL for Staphylococcus aureus and Escherichia coli respectively within 40 min.					
37028863	2	48	theme	packaging	574:582	arg1	CDs-CS					591:596	CDs-CS	591:596	CDs-CS	591:596	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	48	theme	packaging	574:582	arg1	films					584:588	active composite food packaging films	552:588	active composite food packaging films (CDs-CS)	552:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	3	49	theme	containing	618:627	arg1	CDs					629:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	50	contain	had	633:635	arg2	hydrophobicity					685:698	hydrophobicity	685:698	hydrophobicity	685:698	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	50	contain	had	633:635	arg2	protection					670:679	UV protection	667:679	UV protection	667:679	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	50	contain	had	633:635	arg2	properties					655:664	better mechanical properties	637:664	better mechanical properties	637:664	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	50	contain	had	633:635	arg1	CDs					629:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	2	51	theme	photodynamic	329:340	arg1	inactivation					342:353	photodynamic inactivation	329:353	photodynamic inactivation of bactericidal technology in food packaging materials	329:408	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	52	theme	food	569:572	arg1	CDs-CS					591:596	CDs-CS	591:596	CDs-CS	591:596	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	2	52	theme	food	569:572	arg1	films					584:588	active composite food packaging films	552:588	active composite food packaging films (CDs-CS)	552:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	6	53	theme	antimicrobial	1202:1214	arg1	packaging					1221:1229	safe and efficient antimicrobial food packaging	1183:1229	safe and efficient antimicrobial food packaging	1183:1229	This work will provide new insights to explore safe and efficient antimicrobial food packaging.					
37028863	1	54	theme	increased	151:159	arg1	demand					161:166	The increased demand	147:166	The increased demand for food quality and safety	147:194	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	1	55	theme	urgent	229:234	arg1	attention					236:244	urgent attention	229:244	urgent attention	229:244	The increased demand for food quality and safety has led the food industry to pay urgent attention to new packaging materials with antimicrobial activity.					
37028863	2	56	theme	chitosan	513:520	arg1	matrix					522:527	a chitosan matrix	511:527	a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS)	511:597	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	3	57	theme	UV	667:668	arg1	properties					655:664	better mechanical properties	637:664	better mechanical properties	637:664	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	57	theme	UV	667:668	arg1	protection					670:679	UV protection	667:679	UV protection	667:679	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	3	58	theme	chitosan	604:611	arg1	CDs					629:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	2	59	theme	food	385:388	arg1	materials					400:408	food packaging materials	385:408	food packaging materials	385:408	In this study, we combined photodynamic inactivation of bactericidal technology in food packaging materials by incorporating fluorescent carbon quantum dots (CDs) prepared from the natural plant turmeric into a chitosan matrix to prepare a series of active composite food packaging films (CDs-CS).					
37028863	5	60	theme	storage	994:1000	arg1	applications					1002:1013	cold pork storage applications	984:1013	cold pork storage applications	984:1013	In cold pork storage applications, CDs-CS2 films showed inhibition of the growth of colonization in pork and retarded the spoilage of pork within 10 days.					
37028863	3	61	theme	film	613:616	arg1	CDs					629:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs	600:631	The chitosan film containing CDs had better mechanical properties, UV protection and hydrophobicity.					
37028863	6	62	theme	food	1216:1219	arg1	packaging					1221:1229	safe and efficient antimicrobial food packaging	1183:1229	safe and efficient antimicrobial food packaging	1183:1229	This work will provide new insights to explore safe and efficient antimicrobial food packaging.					
36306637	0	0	theme	chiral	83:88	arg1	determination					97:109	the chiral purity determination	79:109	the chiral purity determination of silodosin	79:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	7	1	theme	Requirements	1277:1288	arg1	Harmonization					1250:1262	Harmonization	1250:1262	Harmonization of Technical Requirements for Pharmaceuticals for Human Use	1250:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	6	2	theme	suitable	1122:1129	arg1	shape					1136:1140	suitable peak shape	1122:1140	suitable peak shape	1122:1140	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	1	3	theme	selective	154:162	arg1	antagonist					182:191	a single isomer selective α1-adrenoreceptor antagonist	138:191	a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia	138:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	1	3	theme	selective	154:162	arg1	Silodosin					125:133	Silodosin	125:133	Silodosin	125:133	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	6	4	theme	careful	1080:1086	arg1	adjustment					1091:1100	careful pH adjustment	1080:1100	careful pH adjustment	1080:1100	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	4	5	theme	suitable	556:563	arg1	selector					572:579	suitable chiral selector	556:579	suitable chiral selector	556:579	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	7	6	theme	guideline	1200:1208	arg1	R1					1213:1214	R1	1213:1214	R1	1213:1214	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	7	6	theme	guideline	1200:1208	arg1	Q2					1210:1211	the guideline Q2	1196:1211	the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use	1196:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	1	7	theme	α1-adrenoreceptor	164:180	arg1	antagonist					182:191	a single isomer selective α1-adrenoreceptor antagonist	138:191	a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia	138:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	1	7	theme	α1-adrenoreceptor	164:180	arg1	Silodosin					125:133	Silodosin	125:133	Silodosin	125:133	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	4	8	theme	scouting	616:623	arg1	phase					625:629	the scouting phase	612:629	the scouting phase	612:629	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	5	9	theme	central	789:795	arg1	design					807:812	a face-centered central composite design	773:812	a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV	773:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	2	10	theme	drug	300:303	arg1	purity					286:291	the enantiomeric purity	269:291	the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations	269:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	0	11	theme	purity	90:95	arg1	determination					97:109	the chiral purity determination	79:109	the chiral purity determination of silodosin	79:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	7	12	theme	Human	1314:1318	arg1	Use					1320:1322	Human Use	1314:1322	Human Use	1314:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	5	13	theme	28 kV	992:996	arg1	voltage					981:987	an applied voltage	970:987	an applied voltage of 28 kV	970:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	13	theme	28 kV	992:996	arg1	car-boxymethyl-β-cyclodextrin					902:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	13	theme	28 kV	992:996	arg1	temperature					945:955	a capillary temperature	933:955	a capillary temperature of 17 °C	933:964	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	0	14	theme	silodosin	114:122	arg1	determination					97:109	the chiral purity determination	79:109	the chiral purity determination of silodosin	79:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	3	15	theme	design	488:493	arg1	strategy					495:502	design strategy	488:502	design strategy	488:502	Method development followed a quality by design strategy.					
36306637	5	16	theme	capillary	935:943	arg1	temperature					945:955	a capillary temperature	933:955	a capillary temperature of 17 °C	933:964	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	4	17	theme	critical	694:701	arg1	parameters					711:720	the critical process parameters	690:720	the critical process parameters	690:720	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	5	18	theme	composite	797:805	arg1	design					807:812	a face-centered central composite design	773:812	a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV	773:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	7	19	theme	formulation	1376:1386	arg1	analysis					1343:1350	the analysis	1339:1350	the analysis of a commercial capsule formulation	1339:1386	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	2	20	theme	substance	397:405	arg1	analysis					380:387	the analysis	376:387	the analysis of drug substance as well as pharmaceutical formulations	376:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	7	21	theme	International	1224:1236	arg1	Council					1238:1244	the International Council	1220:1244	the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use	1220:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	2	22	theme	drug	392:395	arg1	substance					397:405	drug substance	392:405	drug substance as well as pharmaceutical formulations	392:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	7	23	theme	Council	1238:1244	arg1	R1					1213:1214	R1	1213:1214	R1	1213:1214	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	7	23	theme	Council	1238:1244	arg1	Q2					1210:1211	the guideline Q2	1196:1211	the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use	1196:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	5	24	contain	containing	882:891	arg2	temperature					945:955	a capillary temperature	933:955	a capillary temperature of 17 °C	933:964	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	24	contain	containing	882:891	arg1	pH					874:875	pH 2.9	874:879	pH 2.9	874:879	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	24	contain	containing	882:891	arg2	voltage					981:987	an applied voltage	970:987	an applied voltage of 28 kV	970:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	24	contain	containing	882:891	arg2	car-boxymethyl-β-cyclodextrin					902:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	24	contain	containing	882:891	arg1	buffer					866:871	the conditions 100 mM sodium phosphate buffer	827:871	the conditions 100 mM sodium phosphate buffer	827:871	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	2	25	theme	electrophoresis	317:331	arg1	method					333:338	a capillary electrophoresis method	305:338	a capillary electrophoresis method	305:338	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	3	26	theme	Method	447:452	arg1	development					454:464	Method development	447:464	Method development	447:464	Method development followed a quality by design strategy.					
36306637	4	27	from	conditions	598:607	arg1	phase					625:629	the scouting phase	612:629	the scouting phase	612:629	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	4	28	theme	starting	589:596	arg1	conditions					598:607	the starting conditions	585:607	the starting conditions	585:607	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	2	29	theme	capillary	307:315	arg1	electrophoresis					317:331	a capillary electrophoresis	305:331	a capillary electrophoresis method	305:338	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	2	30	theme	formulations	433:444	arg1	analysis					380:387	the analysis	376:387	the analysis of drug substance as well as pharmaceutical formulations	376:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	0	31	theme	design-guided	11:23	arg1	development					25:35	design-guided development	11:35	design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin	11:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	6	32	theme	Plackett-Burman	1030:1044	arg1	design					1046:1051	a Plackett-Burman design	1028:1051	a Plackett-Burman design	1028:1051	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	4	33	theme	full	644:647	arg1	design					659:664	a two-level full factorial design	632:664	a two-level full factorial design	632:664	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	4	34	from	selector	572:579	arg1	phase					625:629	the scouting phase	612:629	the scouting phase	612:629	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	2	35	theme	pharmaceutical	418:431	arg1	formulations					433:444	pharmaceutical formulations	418:444	drug substance as well as pharmaceutical formulations	392:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	5	36	theme	conditions	831:840	arg1	pH					874:875	pH 2.9	874:879	pH 2.9	874:879	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	36	theme	conditions	831:840	arg1	buffer					866:871	the conditions 100 mM sodium phosphate buffer	827:871	the conditions 100 mM sodium phosphate buffer	827:871	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	7	37	theme	commercial	1357:1366	arg1	formulation					1376:1386	a commercial capsule formulation	1355:1386	a commercial capsule formulation	1355:1386	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	5	38	theme	40 mg/mL	893:900	arg1	car-boxymethyl-β-cyclodextrin					902:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	4	39	theme	process	703:709	arg1	parameters					711:720	the critical process parameters	690:720	the critical process parameters	690:720	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	1	40	theme	benign	219:224	arg1	hyperplasia					236:246	benign prostatic hyperplasia	219:246	benign prostatic hyperplasia	219:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	5	41	theme	100 mM	842:847	arg1	pH					874:875	pH 2.9	874:879	pH 2.9	874:879	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	41	theme	100 mM	842:847	arg1	buffer					866:871	the conditions 100 mM sodium phosphate buffer	827:871	the conditions 100 mM sodium phosphate buffer	827:871	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	42	theme	face-centered	775:787	arg1	design					807:812	a face-centered central composite design	773:812	a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV	773:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	1	43	theme	prostatic	226:234	arg1	hyperplasia					236:246	benign prostatic hyperplasia	219:246	benign prostatic hyperplasia	219:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	0	44	theme	electrophoresis	52:66	arg1	method					68:73	a capillary electrophoresis method	40:73	a capillary electrophoresis method for the chiral purity determination of silodosin	40:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	4	45	theme	chiral	565:570	arg1	selector					572:579	suitable chiral selector	556:579	suitable chiral selector	556:579	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	5	46	theme	phosphate	856:864	arg1	pH					874:875	pH 2.9	874:879	pH 2.9	874:879	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	46	theme	phosphate	856:864	arg1	buffer					866:871	the conditions 100 mM sodium phosphate buffer	827:871	the conditions 100 mM sodium phosphate buffer	827:871	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	47	theme	applied	973:979	arg1	voltage					981:987	an applied voltage	970:987	an applied voltage of 28 kV	970:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	0	48	theme	capillary	42:50	arg1	method					68:73	a capillary electrophoresis method	40:73	a capillary electrophoresis method for the chiral purity determination of silodosin	40:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	6	49	theme	Robustness	999:1008	arg1	testing					1010:1016	Robustness testing	999:1016	Robustness testing employing a Plackett-Burman design	999:1051	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	7	50	theme	Technical	1267:1275	arg1	Requirements					1277:1288	Technical Requirements	1267:1288	Technical Requirements for Pharmaceuticals for Human Use	1267:1322	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	5	51	theme	final	727:731	arg1	optimization					740:751	The final method optimization	723:751	The final method optimization	723:751	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	52	theme	sodium	849:854	arg1	pH					874:875	pH 2.9	874:879	pH 2.9	874:879	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	52	theme	sodium	849:854	arg1	buffer					866:871	the conditions 100 mM sodium phosphate buffer	827:871	the conditions 100 mM sodium phosphate buffer	827:871	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	2	53	theme	enantiomeric	273:284	arg1	purity					286:291	the enantiomeric purity	269:291	the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations	269:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	1	54	theme	hyperplasia	236:246	arg1	treatment					206:214	the treatment	202:214	the treatment of benign prostatic hyperplasia	202:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	5	55	theme	method	733:738	arg1	optimization					740:751	The final method optimization	723:751	The final method optimization	723:751	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	2	56	dep	purity	286:291	arg1	developed					344:352	developed	344:352	was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations	340:444	In order to control the enantiomeric purity of the drug a capillary electrophoresis method was developed that is applicable to the analysis of drug substance as well as pharmaceutical formulations.					
36306637	4	57	theme	two-level	634:642	arg1	design					659:664	a two-level full factorial design	632:664	a two-level full factorial design	632:664	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	5	58	theme	17 °C	960:964	arg1	voltage					981:987	an applied voltage	970:987	an applied voltage of 28 kV	970:996	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	58	theme	17 °C	960:964	arg1	car-boxymethyl-β-cyclodextrin					902:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	40 mg/mL car-boxymethyl-β-cyclodextrin	893:930	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	5	58	theme	17 °C	960:964	arg1	temperature					945:955	a capillary temperature	933:955	a capillary temperature of 17 °C	933:964	The final method optimization was performed using a face-centered central composite design resulting in the conditions 100 mM sodium phosphate buffer, pH 2.9, containing 40 mg/mL car-boxymethyl-β-cyclodextrin, a capillary temperature of 17 °C and an applied voltage of 28 kV.					
36306637	6	59	theme	peak	1131:1134	arg1	shape					1136:1140	suitable peak shape	1122:1140	suitable peak shape	1122:1140	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	1	60	theme	single	140:145	arg1	antagonist					182:191	a single isomer selective α1-adrenoreceptor antagonist	138:191	a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia	138:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	1	60	theme	single	140:145	arg1	Silodosin					125:133	Silodosin	125:133	Silodosin	125:133	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	7	61	theme	capsule	1368:1374	arg1	formulation					1376:1386	a commercial capsule formulation	1355:1386	a commercial capsule formulation	1355:1386	The method was validated according to the guideline Q2(R1) of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use and applied to the analysis of a commercial capsule formulation.					
36306637	6	62	theme	adjustment	1091:1100	arg1	importance					1066:1075	the importance	1062:1075	the importance of careful pH adjustment in order to achieve suitable peak shape and resolution	1062:1155	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	0	63	theme	method	68:73	arg1	development					25:35	design-guided development	11:35	design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin	11:122	Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin.					
36306637	4	64	theme	carboxymethyl-β-cyclodextrin	524:551	arg1	selection					511:519	selection	511:519	selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase	511:629	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
36306637	6	65	theme	pH	1088:1089	arg1	adjustment					1091:1100	careful pH adjustment	1080:1100	careful pH adjustment	1080:1100	Robustness testing employing a Plackett-Burman design revealed the importance of careful pH adjustment in order to achieve suitable peak shape and resolution.					
36306637	1	66	theme	isomer	147:152	arg1	antagonist					182:191	a single isomer selective α1-adrenoreceptor antagonist	138:191	a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia	138:246	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	1	66	theme	isomer	147:152	arg1	Silodosin					125:133	Silodosin	125:133	Silodosin	125:133	Silodosin is a single isomer selective α1-adrenoreceptor antagonist used for the treatment of benign prostatic hyperplasia.					
36306637	4	67	theme	factorial	649:657	arg1	design					659:664	a two-level full factorial design	632:664	a two-level full factorial design	632:664	After selection of carboxymethyl-β-cyclodextrin as suitable chiral selector and the starting conditions in the scouting phase, a two-level full factorial design was applied to identify the critical process parameters.					
37099026	3	0	dep	simulate	741:748	arg1	improve					807:813	improve	807:813	improve the convenience of clinical implantation	807:854	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	6	1	theme	osteogenic	1293:1302	arg1	activity					1304:1311	osteogenic activity	1293:1311	osteogenic activity	1293:1311	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	3	2	theme	bone	777:780	arg1	tissue					782:787	bone tissue	777:787	bone tissue	777:787	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	3	3	theme	fiber	759:763	arg1	skeleton					765:772	collagen fiber skeleton	750:772	collagen fiber skeleton	750:772	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	0	4	theme	Angiogenic	86:95	arg1	Activities					97:106	Antibacterial and Angiogenic Activities	68:106	Antibacterial and Angiogenic Activities	68:106	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	8	5	theme	YAP/TAZ	1572:1578	arg1	expression					1558:1567	the expression	1554:1567	the expression of YAP/TAZ	1554:1578	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	3	6	theme	oriented	673:680	arg1	skeleton					692:699	oriented cellulose skeleton	673:699	oriented cellulose skeleton	673:699	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	1	7	theme	bone	270:273	arg1	matrix					289:294	bone extracellular matrix	270:294	bone extracellular matrix	270:294	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	0	8	theme	Bone	112:115	arg1	Repair					117:122	Bone Repair	112:122	Bone Repair	112:122	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	8	9	theme	mechanical	1460:1469	arg1	characteristics					1471:1485	the mechanical characteristics	1456:1485	the mechanical characteristics of the scaffolds	1456:1502	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	7	10	theme	Runx-2	1432:1437	arg1	expression					1418:1427	the expression	1414:1427	the expression of Runx-2	1414:1437	Interestingly, DMOG can also activate the YAP/TAZ by upregulating the expression of Runx-2.					
37099026	9	11	theme	defects	1754:1760	arg1	treatment					1736:1744	the treatment	1732:1744	the treatment of bone defects	1732:1760	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	1	12	theme	extracellular	275:287	arg1	matrix					289:294	bone extracellular matrix	270:294	bone extracellular matrix	270:294	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	5	13	with	scaffold	1060:1067	arg1	activity					1093:1100	good antibacterial activity	1074:1100	good antibacterial activity	1074:1100	Among them, CQS endows the scaffold with good antibacterial activity, while DMOG significantly improves the scaffold's osteogenic and angiogenic activities.					
37099026	1	14	theme	huge	389:392	arg1	challenge					394:402	a huge challenge	387:402	a huge challenge	387:402	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	6	15	theme	signaling	1329:1337	arg1	pathway					1339:1345	YAP/TAZ signaling pathway	1321:1345	YAP/TAZ signaling pathway	1321:1345	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	6	16	theme	elastic	1220:1226	arg1	characteristics					1228:1242	the anisotropic and elastic characteristics	1200:1242	the anisotropic and elastic characteristics of the scaffold	1200:1258	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	2	17	theme	osteogenic	541:550	arg1	activities					567:576	good antibacterial, osteogenic and angiogenic activities	521:576	good antibacterial, osteogenic and angiogenic activities	521:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	4	18	theme	quaternary	880:889	arg1	CQS					906:908	CQS	906:908	CQS	906:908	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	4	18	theme	quaternary	880:889	arg1	salt					900:903	chitosan quaternary ammonium salt	871:903	chitosan quaternary ammonium salt (CQS)	871:909	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	3	19	theme	implantation	843:854	arg1	convenience					819:829	the convenience	815:829	the convenience of clinical implantation	815:854	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	4	20	theme	elastic	986:992	arg1	scaffold					994:1001	the wood-derived elastic scaffold	969:1001	the wood-derived elastic scaffold through a polydopamine layer	969:1030	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	4	21	theme	chitosan	871:878	arg1	CQS					906:908	CQS	906:908	CQS	906:908	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	4	21	theme	chitosan	871:878	arg1	salt					900:903	chitosan quaternary ammonium salt	871:903	chitosan quaternary ammonium salt (CQS)	871:909	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	9	22	theme	potential	1707:1715	arg1	application					1717:1727	potential application	1707:1727	potential application	1707:1727	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	2	23	theme	porous	482:487	arg1	structure					489:497	anisotropic porous structure	470:497	anisotropic porous structure	470:497	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	0	24	theme	Elastic	7:13	arg1	Scaffold					54:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold	0:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.	0:123	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	3	25	theme	collagen	750:757	arg1	skeleton					765:772	collagen fiber skeleton	750:772	collagen fiber skeleton	750:772	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	3	26	with	scaffold	659:666	arg1	skeleton					692:699	oriented cellulose skeleton	673:699	oriented cellulose skeleton	673:699	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	3	26	with	scaffold	659:666	arg1	elasticity					710:719	high elasticity	705:719	high elasticity	705:719	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	9	27	link	wood-derived	1655:1666	arg1	scaffold					1678:1685	this wood-derived composite scaffold	1650:1685	this wood-derived composite scaffold	1650:1685	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	4	28	theme	wood-derived	973:984	arg1	scaffold					994:1001	the wood-derived elastic scaffold	969:1001	the wood-derived elastic scaffold through a polydopamine layer	969:1030	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	2	29	theme	anisotropic	470:480	arg1	structure					489:497	anisotropic porous structure	470:497	anisotropic porous structure	470:497	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	3	30	theme	high	705:708	arg1	elasticity					710:719	high elasticity	705:719	high elasticity	705:719	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	6	31	theme	YAP/TAZ	1321:1327	arg1	pathway					1339:1345	YAP/TAZ signaling pathway	1321:1345	YAP/TAZ signaling pathway	1321:1345	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	1	32	theme	growing	206:212	arg1	demand					214:219	the rapidly growing demand	194:219	the rapidly growing demand for bone implants	194:237	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	0	33	theme	Anisotropic	19:29	arg1	Scaffold					54:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold	0:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.	0:123	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	8	34	theme	osteogenic	1611:1620	arg1	differentiation					1622:1636	osteogenic differentiation	1611:1636	osteogenic differentiation	1611:1636	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	3	35	theme	natural	586:592	arg1	wood					594:597	natural wood	586:597	natural wood	586:597	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	2	36	theme	composite	446:454	arg1	scaffold					456:463	a wood-derived composite scaffold	431:463	a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities	431:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	1	37	with	scaffolds	255:263	arg1	matrix					289:294	bone extracellular matrix	270:294	bone extracellular matrix	270:294	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	5	38	dep	osteogenic	1152:1161	arg1	activities					1178:1187	activities	1178:1187	activities	1178:1187	Among them, CQS endows the scaffold with good antibacterial activity, while DMOG significantly improves the scaffold's osteogenic and angiogenic activities.					
37099026	3	39	theme	cellulose	682:690	arg1	skeleton					692:699	oriented cellulose skeleton	673:699	oriented cellulose skeleton	673:699	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	9	40	theme	composite	1668:1676	arg1	scaffold					1678:1685	this wood-derived composite scaffold	1650:1685	this wood-derived composite scaffold	1650:1685	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	2	41	theme	wood-derived	433:444	arg1	scaffold					456:463	a wood-derived composite scaffold	431:463	a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities	431:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	0	42	theme	Composite	44:52	arg1	Scaffold					54:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold	0:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.	0:123	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	1	43	theme	suitable	313:320	arg1	properties					333:342	suitable mechanical properties	313:342	suitable mechanical properties	313:342	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	8	44	theme	scaffolds	1494:1502	arg1	characteristics					1471:1485	the mechanical characteristics	1456:1485	the mechanical characteristics of the scaffolds	1456:1502	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	8	44	theme	scaffolds	1494:1502	arg1	DMOG					1521:1524	the modified DMOG	1508:1524	the modified DMOG	1508:1524	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	1	45	theme	bone	225:228	arg1	implants					230:237	bone implants	225:237	bone implants	225:237	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	0	46	theme	Wood-Derived	31:42	arg1	Scaffold					54:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold	0:61	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.	0:123	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	1	47	theme	mechanical	322:331	arg1	properties					333:342	suitable mechanical properties	313:342	suitable mechanical properties	313:342	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	2	48	theme	high	500:503	arg1	elasticity					505:514	high elasticity	500:514	high elasticity	500:514	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	8	49	theme	modified	1512:1519	arg1	DMOG					1521:1524	the modified DMOG	1508:1524	the modified DMOG	1508:1524	That is to say, the mechanical characteristics of the scaffolds and the modified DMOG can synergistically enhance the expression of YAP/TAZ, thereby effectively promoting osteogenic differentiation.					
37099026	3	50	link	wood-derived	646:657	arg1	scaffold					659:666	a wood-derived scaffold	644:666	a wood-derived scaffold	644:666	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	2	51	theme	angiogenic	556:565	arg1	activities					567:576	good antibacterial, osteogenic and angiogenic activities	521:576	good antibacterial, osteogenic and angiogenic activities	521:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	2	52	theme	good	521:524	arg1	activities					567:576	good antibacterial, osteogenic and angiogenic activities	521:576	good antibacterial, osteogenic and angiogenic activities	521:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	6	53	theme	cell	1271:1274	arg1	polarization					1276:1287	cell polarization	1271:1287	cell polarization	1271:1287	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	2	54	with	scaffold	456:463	arg1	activities					567:576	good antibacterial, osteogenic and angiogenic activities	521:576	good antibacterial, osteogenic and angiogenic activities	521:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	2	54	with	scaffold	456:463	arg1	structure					489:497	anisotropic porous structure	470:497	anisotropic porous structure	470:497	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	2	54	with	scaffold	456:463	arg1	elasticity					505:514	high elasticity	500:514	high elasticity	500:514	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	1	55	theme	Scaffold-based	125:138	arg1	engineering					147:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	1	55	theme	Scaffold-based	125:138	arg1	strategy					174:181	a promising strategy	162:181	a promising strategy to address the rapidly growing demand for bone implants	162:237	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	9	56	contain	have	1702:1705	arg1	scaffold					1678:1685	this wood-derived composite scaffold	1650:1685	this wood-derived composite scaffold	1650:1685	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	9	56	contain	have	1702:1705	arg2	application					1717:1727	potential application	1707:1727	potential application	1707:1727	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	3	57	theme	alkaline	616:623	arg1	solution					625:632	alkaline solution	616:632	alkaline solution	616:632	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	9	58	theme	bone	1749:1752	arg1	defects					1754:1760	bone defects	1749:1760	bone defects	1749:1760	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	1	59	theme	tissue	140:145	arg1	engineering					147:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	1	59	theme	tissue	140:145	arg1	strategy					174:181	a promising strategy	162:181	a promising strategy to address the rapidly growing demand for bone implants	162:237	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	1	60	theme	multiple	348:355	arg1	activities					368:377	multiple biological activities	348:377	multiple biological activities	348:377	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	4	61	link	wood-derived	973:984	arg1	scaffold					994:1001	the wood-derived elastic scaffold	969:1001	the wood-derived elastic scaffold through a polydopamine layer	969:1030	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	5	62	theme	good	1074:1077	arg1	activity					1093:1100	good antibacterial activity	1074:1100	good antibacterial activity	1074:1100	Among them, CQS endows the scaffold with good antibacterial activity, while DMOG significantly improves the scaffold's osteogenic and angiogenic activities.					
37099026	3	63	theme	wood-derived	646:657	arg1	scaffold					659:666	a wood-derived scaffold	644:666	a wood-derived scaffold	644:666	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	9	64	theme	wood-derived	1655:1666	arg1	scaffold					1678:1685	this wood-derived composite scaffold	1650:1685	this wood-derived composite scaffold	1650:1685	Therefore, this wood-derived composite scaffold is expected to have potential application in the treatment of bone defects.					
37099026	4	65	theme	polydopamine	1013:1024	arg1	layer					1026:1030	a polydopamine layer	1011:1030	a polydopamine layer	1011:1030	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	6	66	theme	anisotropic	1204:1214	arg1	characteristics					1228:1242	the anisotropic and elastic characteristics	1200:1242	the anisotropic and elastic characteristics of the scaffold	1200:1258	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	5	67	theme	antibacterial	1079:1091	arg1	activity					1093:1100	good antibacterial activity	1074:1100	good antibacterial activity	1074:1100	Among them, CQS endows the scaffold with good antibacterial activity, while DMOG significantly improves the scaffold's osteogenic and angiogenic activities.					
37099026	6	68	theme	scaffold	1251:1258	arg1	characteristics					1228:1242	the anisotropic and elastic characteristics	1200:1242	the anisotropic and elastic characteristics of the scaffold	1200:1258	Moreover, the anisotropic and elastic characteristics of the scaffold can induce cell polarization and osteogenic activity through YAP/TAZ signaling pathway.					
37099026	3	69	theme	clinical	834:841	arg1	implantation					843:854	clinical implantation	834:854	clinical implantation	834:854	First, natural wood was treated with alkaline solution to obtain a wood-derived scaffold with oriented cellulose skeleton and high elasticity, which can not only simulate collagen fiber skeleton in bone tissue, but also greatly improve the convenience of clinical implantation.					
37099026	2	70	theme	antibacterial	526:538	arg1	activities					567:576	good antibacterial, osteogenic and angiogenic activities	521:576	good antibacterial, osteogenic and angiogenic activities	521:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	2	71	link	wood-derived	433:444	arg1	scaffold					456:463	a wood-derived composite scaffold	431:463	a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities	431:576	Here, we aimed to develop a wood-derived composite scaffold with anisotropic porous structure, high elasticity, and good antibacterial, osteogenic and angiogenic activities.					
37099026	0	72	with	Scaffold	54:61	arg1	Activities					97:106	Antibacterial and Angiogenic Activities	68:106	Antibacterial and Angiogenic Activities	68:106	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	1	73	theme	developing	244:253	arg1	scaffolds					255:263	developing scaffolds	244:263	developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities	244:377	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	0	74	theme	Antibacterial	68:80	arg1	Activities					97:106	Antibacterial and Angiogenic Activities	68:106	Antibacterial and Angiogenic Activities	68:106	Highly Elastic and Anisotropic Wood-Derived Composite Scaffold with Antibacterial and Angiogenic Activities for Bone Repair.					
37099026	1	75	theme	biological	357:366	arg1	activities					368:377	multiple biological activities	348:377	multiple biological activities	348:377	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	4	76	theme	ammonium	891:898	arg1	CQS					906:908	CQS	906:908	CQS	906:908	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	4	76	theme	ammonium	891:898	arg1	salt					900:903	chitosan quaternary ammonium salt	871:903	chitosan quaternary ammonium salt (CQS)	871:909	Subsequently, chitosan quaternary ammonium salt (CQS) and dimethyloxalylglycine (DMOG) were further modified on the wood-derived elastic scaffold through a polydopamine layer.					
37099026	1	77	theme	promising	164:172	arg1	engineering					147:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering	125:157	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37099026	1	77	theme	promising	164:172	arg1	strategy					174:181	a promising strategy	162:181	a promising strategy to address the rapidly growing demand for bone implants	162:237	Scaffold-based tissue engineering is a promising strategy to address the rapidly growing demand for bone implants, but developing scaffolds with bone extracellular matrix like structures, suitable mechanical properties and multiple biological activities remains a huge challenge.					
37003382	0	0	theme	chemical	83:90	arg1	composition					92:102	chemical composition	83:102	chemical composition	83:102	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	4	1	theme	granatum	641:648	arg1	oil					650:652	P. granatum oil	638:652	P. granatum oil	638:652	However, P. granatum oil produced high droplets size.					
37003382	2	2	theme	following	347:355	arg1	ratios					357:362	the following ratios	343:362	the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil	343:429	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	8	3	theme	essential	1075:1083	arg1	MIC = 500					1091:1099	MIC = 500	1091:1099	MIC = 500	1091:1099	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	8	3	theme	essential	1075:1083	arg1	oils					1085:1088	essential oils	1075:1088	essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium)	1075:1148	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	8	3	theme	essential	1075:1083	arg1	650 mg/L					1105:1112	650 mg/L	1105:1112	650 mg/L	1105:1112	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	0	4	from	impacts	4:10	arg1	diversity					69:77	microbial diversity	59:77	microbial diversity	59:77	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	0	4	from	impacts	4:10	arg1	composition					92:102	chemical composition	83:102	chemical composition	83:102	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	4	5	theme	P.	638:639	arg1	oil					650:652	P. granatum oil	638:652	P. granatum oil	638:652	However, P. granatum oil produced high droplets size.					
37003382	2	6	theme	essential	489:497	arg1	oils					499:502	four essential oils	484:502	four essential oils	484:502	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	10	7	theme	active	1292:1297	arg1	products					1299:1306	the most active products	1283:1306	the most active products against E.coli	1283:1321	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	10	7	theme	active	1292:1297	arg1	nanoemulsion					1265:1276	its nanoemulsion	1261:1276	its nanoemulsion	1261:1276	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	10	7	theme	active	1292:1297	arg1	limon					1251:1255	C. limon	1248:1255	C. limon	1248:1255	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	11	8	theme	meat	1422:1425	arg1	life					1414:1417	the shelf life	1404:1417	the shelf life of meat	1404:1425	These results suggest that chitosan-essential oil nanoemulsions may help extend the shelf life of meat by acting as antimicrobial agents.					
37003382	4	9	theme	droplets	668:675	arg1	size					677:680	high droplets size	663:680	high droplets size	663:680	However, P. granatum oil produced high droplets size.					
37003382	0	10	theme	minced	120:125	arg1	meat					127:130	refrigerated minced meat	107:130	refrigerated minced meat	107:130	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	6	11	theme	antibacterial	842:854	arg1	activity					856:863	The in vivo antibacterial activity	830:863	The in vivo antibacterial activity	830:863	The in vivo antibacterial activity was further investigated on minced beef meat during storage at 4 °C for ten days.					
37003382	8	12	dep	oils	1085:1088	arg1	MIC = 500					1091:1099	MIC = 500	1091:1099	MIC = 500	1091:1099	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	8	12	dep	oils	1085:1088	arg1	oils					1085:1088	essential oils	1075:1088	essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium)	1075:1148	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	8	12	dep	oils	1085:1088	arg1	650 mg/L					1105:1112	650 mg/L	1105:1112	650 mg/L	1105:1112	Chitosan was more effective as an antibacterial than essential oils (MIC = 500 and 650 mg/L against E. coli and S. typhimunium).					
37003382	11	13	theme	antimicrobial	1440:1452	arg1	agents					1454:1459	antimicrobial agents	1440:1459	antimicrobial agents	1440:1459	These results suggest that chitosan-essential oil nanoemulsions may help extend the shelf life of meat by acting as antimicrobial agents.					
37003382	11	14	theme	chitosan-essential	1351:1368	arg1	nanoemulsions					1374:1386	chitosan-essential oil nanoemulsions	1351:1386	chitosan-essential oil nanoemulsions	1351:1386	These results suggest that chitosan-essential oil nanoemulsions may help extend the shelf life of meat by acting as antimicrobial agents.					
37003382	0	15	theme	refrigerated	107:118	arg1	meat					127:130	refrigerated minced meat	107:130	refrigerated minced meat	107:130	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	2	16	dep	ratios	357:362	arg1	oil					416:418	essential oil	406:418	the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil	343:429	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	16	dep	ratios	357:362	arg1	oil					427:429	olive oil	421:429	the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil	343:429	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	16	dep	ratios	357:362	arg1	0.5:0.5:4					365:373	0.5:0.5:4	365:373	0.5:0.5:4	365:373	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	16	dep	ratios	357:362	arg1	2:3:4					387:391	2:3:4	387:391	2:3:4	387:391	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	16	dep	ratios	357:362	arg1	1:1:4					376:380	1:1:4	376:380	1:1:4	376:380	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	1	17	theme	granatum	175:182	arg1	oils					143:146	Essential oils	133:146	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier	133:242	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	6	18	theme	in	834:835	arg1	activity					856:863	The in vivo antibacterial activity	830:863	The in vivo antibacterial activity	830:863	The in vivo antibacterial activity was further investigated on minced beef meat during storage at 4 °C for ten days.					
37003382	11	19	theme	oil	1370:1372	arg1	nanoemulsions					1374:1386	chitosan-essential oil nanoemulsions	1351:1386	chitosan-essential oil nanoemulsions	1351:1386	These results suggest that chitosan-essential oil nanoemulsions may help extend the shelf life of meat by acting as antimicrobial agents.					
37003382	1	20	from	oils	143:146	arg1	oil					227:229	olive oil	221:229	olive oil	221:229	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	5	21	theme	pathogenic	759:768	arg1	coli					797:800	Escherichia coli	785:800	Escherichia coli	785:800	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	5	21	theme	pathogenic	759:768	arg1	typhimunium					817:827	Salmonella typhimunium	806:827	Salmonella typhimunium	806:827	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	5	21	theme	pathogenic	759:768	arg1	bacteria					775:782	two pathogenic food bacteria	755:782	two pathogenic food bacteria	755:782	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	3	22	theme	nanoemulsions	538:550	arg1	characterization					518:533	the characterization	514:533	the characterization of nanoemulsions	514:550	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	1	23	theme	Thymus	185:190	arg1	vulgaris					192:199	Thymus vulgaris	185:199	Thymus vulgaris	185:199	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	0	24	theme	chitosan-essential	15:32	arg1	nanoemulsions					38:50	chitosan-essential oil nanoemulsions	15:50	chitosan-essential oil nanoemulsions	15:50	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	1	25	theme	biopolymer	260:269	arg1	chitosan					271:278	biopolymer chitosan	260:278	biopolymer chitosan	260:278	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	3	26	theme	M.	553:554	arg1	oils					592:595	M. piperita, T. vulgaris, and C. limon oils	553:595	M. piperita, T. vulgaris, and C. limon oils	553:595	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	0	27	dep	diversity	69:77	arg1	the					55:57	the	55:57	the	55:57	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	2	28	theme	chitosan	396:403	arg1	1:1:4					376:380	1:1:4	376:380	1:1:4	376:380	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	28	theme	chitosan	396:403	arg1	2:3:4					387:391	2:3:4	387:391	2:3:4	387:391	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	2	28	theme	chitosan	396:403	arg1	0.5:0.5:4					365:373	0.5:0.5:4	365:373	0.5:0.5:4	365:373	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	0	29	theme	meat	127:130	arg1	diversity					69:77	microbial diversity	59:77	microbial diversity	59:77	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	0	29	theme	meat	127:130	arg1	composition					92:102	chemical composition	83:102	chemical composition	83:102	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	10	30	theme	In	1220:1221	arg1	studies					1228:1234	In vivo studies	1220:1234	In vivo studies	1220:1234	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	0	31	theme	nanoemulsions	38:50	arg1	impacts					4:10	The impacts	0:10	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.	0:131	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	6	32	dep	in	834:835	arg1	vivo					837:840	vivo	837:840	vivo	837:840	The in vivo antibacterial activity was further investigated on minced beef meat during storage at 4 °C for ten days.					
37003382	1	33	theme	Citrus	205:210	arg1	limon					212:216	Citrus limon	205:216	Citrus limon	205:216	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	0	34	theme	oil	34:36	arg1	nanoemulsions					38:50	chitosan-essential oil nanoemulsions	15:50	chitosan-essential oil nanoemulsions	15:50	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	5	35	theme	antimicrobial	724:736	arg1	activity					738:745	antimicrobial activity	724:745	antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium	724:827	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	3	36	theme	C.	583:584	arg1	oils					592:595	M. piperita, T. vulgaris, and C. limon oils	553:595	M. piperita, T. vulgaris, and C. limon oils	553:595	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	2	37	theme	essential	406:414	arg1	oil					416:418	essential oil	406:418	the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil	343:429	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	7	38	theme	MIC	960:962	arg1	values					964:969	the MIC values	956:969	the MIC values	956:969	Based on the MIC values, E. coli was more susceptible than S. typhimunium.					
37003382	5	39	theme	food	770:773	arg1	coli					797:800	Escherichia coli	785:800	Escherichia coli	785:800	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	5	39	theme	food	770:773	arg1	typhimunium					817:827	Salmonella typhimunium	806:827	Salmonella typhimunium	806:827	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	5	39	theme	food	770:773	arg1	bacteria					775:782	two pathogenic food bacteria	755:782	two pathogenic food bacteria	755:782	The products were evaluated in vitro for antimicrobial activity against two pathogenic food bacteria, Escherichia coli and Salmonella typhimunium.					
37003382	1	40	from	oil	227:229	arg1	oils					143:146	Essential oils	133:146	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier	133:242	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	3	41	theme	limon	586:590	arg1	oils					592:595	M. piperita, T. vulgaris, and C. limon oils	553:595	M. piperita, T. vulgaris, and C. limon oils	553:595	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	10	42	theme	C.	1248:1249	arg1	limon					1251:1255	C. limon	1248:1255	C. limon	1248:1255	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	10	42	theme	C.	1248:1249	arg1	nanoemulsion					1265:1276	its nanoemulsion	1261:1276	its nanoemulsion	1261:1276	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	10	42	theme	C.	1248:1249	arg1	products					1299:1306	the most active products	1283:1306	the most active products against E.coli	1283:1321	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	2	43	theme	olive	421:425	arg1	oil					427:429	olive oil	421:429	the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil	343:429	The formulations were prepared using the following ratios: 0.5:0.5:4, 1:1:4, and 2:3:4 of chitosan: essential oil: olive oil, respectively, representing 12 formulations based on four essential oils.					
37003382	6	44	theme	beef	900:903	arg1	meat					905:908	minced beef meat	893:908	minced beef meat	893:908	The in vivo antibacterial activity was further investigated on minced beef meat during storage at 4 °C for ten days.					
37003382	1	45	dep	granatum	175:182	arg1	vulgaris					192:199	Thymus vulgaris	185:199	Thymus vulgaris	185:199	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	1	45	dep	granatum	175:182	arg1	limon					212:216	Citrus limon	205:216	Citrus limon	205:216	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	9	46	theme	tested	1161:1166	arg1	products					1168:1175	the tested products	1157:1175	the tested products	1157:1175	Among the tested products, C. limon had a more antibacterial effect.					
37003382	11	47	theme	shelf	1408:1412	arg1	life					1414:1417	the shelf life	1404:1417	the shelf life of meat	1404:1425	These results suggest that chitosan-essential oil nanoemulsions may help extend the shelf life of meat by acting as antimicrobial agents.					
37003382	6	48	theme	minced	893:898	arg1	meat					905:908	minced beef meat	893:908	minced beef meat	893:908	The in vivo antibacterial activity was further investigated on minced beef meat during storage at 4 °C for ten days.					
37003382	9	49	theme	C.	1178:1179	arg1	limon					1181:1185	C. limon	1178:1185	C. limon	1178:1185	Among the tested products, C. limon had a more antibacterial effect.					
37003382	1	50	theme	Essential	133:141	arg1	oils					143:146	Essential oils	133:146	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier	133:242	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	10	51	dep	In	1220:1221	arg1	vivo					1223:1226	vivo	1223:1226	vivo	1223:1226	In vivo studies proved that C. limon and its nanoemulsion were the most active products against E.coli.					
37003382	4	52	theme	high	663:666	arg1	size					677:680	high droplets size	663:680	high droplets size	663:680	However, P. granatum oil produced high droplets size.					
37003382	1	53	theme	olive	221:225	arg1	oil					227:229	olive oil	221:229	olive oil	221:229	Essential oils of Mentha piperita, Punica granatum, Thymus vulgaris and Citrus limon in olive oil as a carrier were mixed with biopolymer chitosan to prepare nanoemulsions.					
37003382	3	54	theme	smallest	610:617	arg1	droplets					619:626	the smallest droplets	606:626	the smallest droplets	606:626	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	3	55	theme	T.	566:567	arg1	oils					592:595	M. piperita, T. vulgaris, and C. limon oils	553:595	M. piperita, T. vulgaris, and C. limon oils	553:595	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	3	56	dep	T.	566:567	arg1	vulgaris					569:576	T. vulgaris	566:576	T. vulgaris	566:576	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	3	57	dep	M.	553:554	arg1	piperita					556:563	M. piperita	553:563	M. piperita	553:563	Based on the characterization of nanoemulsions, M. piperita, T. vulgaris, and C. limon oils produced the smallest droplets.					
37003382	0	58	theme	microbial	59:67	arg1	diversity					69:77	microbial diversity	59:77	microbial diversity	59:77	The impacts of chitosan-essential oil nanoemulsions on the microbial diversity and chemical composition of refrigerated minced meat.					
37003382	9	59	theme	antibacterial	1198:1210	arg1	effect					1212:1217	a more antibacterial effect	1191:1217	a more antibacterial effect	1191:1217	Among the tested products, C. limon had a more antibacterial effect.					
37003382	9	60	contain	had	1187:1189	arg2	effect					1212:1217	a more antibacterial effect	1191:1217	a more antibacterial effect	1191:1217	Among the tested products, C. limon had a more antibacterial effect.					
37003382	9	60	contain	had	1187:1189	arg1	limon					1181:1185	C. limon	1178:1185	C. limon	1178:1185	Among the tested products, C. limon had a more antibacterial effect.					
36241293	0	0	theme	emulsification	73:86	arg1	performance					88:98	emulsification performance	73:98	emulsification performance	73:98	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	7	1	theme	pectin	1039:1044	arg1	properties					1025:1034	the physicochemical properties	1005:1034	the physicochemical properties of pectin	1005:1044	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	3	2	dep	esterification	442:455	arg1	the					438:440	the	438:440	the	438:440	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	1	3	theme	Parched	212:218	arg1	PH					232:233	PH	232:233	PH	232:233	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	3	theme	Parched	212:218	arg1	processing					220:229	Parched processing	212:229	Parched processing (PH)	212:234	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	2	4	theme	characterization	385:400	arg1	methods					402:408	characterization methods	385:408	characterization methods	385:408	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	0	5	from	Effect	0:5	arg1	properties					58:67	properties	58:67	properties	58:67	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	0	5	from	Effect	0:5	arg1	performance					88:98	emulsification performance	73:98	emulsification performance	73:98	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	7	6	theme	physicochemical	1009:1023	arg1	properties					1025:1034	the physicochemical properties	1005:1034	the physicochemical properties of pectin	1005:1044	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	4	7	contain	had	564:566	arg2	464.42 × 103 g/mol					621:638	464.42 × 103 g/mol	621:638	464.42 × 103 g/mol	621:638	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	7	contain	had	564:566	arg1	FHP					560:562	FHP	560:562	FHP	560:562	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	7	contain	had	564:566	arg2	weight					613:618	molecular weight	603:618	molecular weight	603:618	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	7	contain	had	564:566	arg2	viscosity					589:597	apparent viscosity	580:597	apparent viscosity	580:597	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	8	theme	molecular	603:611	arg1	weight					613:618	molecular weight	603:618	molecular weight	603:618	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	0	9	theme	pectin	112:117	arg1	properties					58:67	properties	58:67	properties	58:67	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	0	9	theme	pectin	112:117	arg1	performance					88:98	emulsification performance	73:98	emulsification performance	73:98	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	6	10	theme	better	880:885	arg1	performance					887:897	better performance	880:897	better performance	880:897	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	1	11	theme	hot	164:166	arg1	drying					172:177	hot air drying	164:177	hot air drying (HH)	164:182	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	11	theme	hot	164:166	arg1	HH					180:181	HH	180:181	HH	180:181	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	0	12	theme	hawthorn	103:110	arg1	pectin					112:117	hawthorn pectin	103:117	hawthorn pectin	103:117	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	2	13	theme	pectins	297:303	arg1	types					288:292	Five types	283:292	Five types of pectins (HHP, FHP, PHP, CHP, BHP)	283:329	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	7	14	theme	hawthorn	987:994	arg1	methods					976:982	different processing methods	955:982	different processing methods of hawthorn	955:994	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	4	15	theme	apparent	580:587	arg1	viscosity					589:597	apparent viscosity	580:597	apparent viscosity	580:597	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	15	theme	apparent	580:587	arg1	464.42 × 103 g/mol					621:638	464.42 × 103 g/mol	621:638	464.42 × 103 g/mol	621:638	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	5	16	theme	monosaccharide	705:718	arg1	composition					720:730	monosaccharide composition	705:730	monosaccharide composition	705:730	PHP and CHP differ in galacturonic acid, molecular weight, and monosaccharide composition depending on the time of processing.					
36241293	7	17	theme	processing	965:974	arg1	methods					976:982	different processing methods	955:982	different processing methods of hawthorn	955:994	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	4	18	theme	highest	572:578	arg1	viscosity					589:597	apparent viscosity	580:597	apparent viscosity	580:597	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	4	18	theme	highest	572:578	arg1	464.42 × 103 g/mol					621:638	464.42 × 103 g/mol	621:638	464.42 × 103 g/mol	621:638	FHP had the highest apparent viscosity and molecular weight (464.42 × 103 g/mol).					
36241293	7	19	with	pectin	1051:1056	arg1	properties					1072:1081	specific properties	1063:1081	specific properties	1063:1081	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	0	20	theme	processing	20:29	arg1	methods					31:37	different processing methods	10:37	different processing methods of hawthorn	10:49	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	0	21	dep	properties	58:67	arg1	the					54:56	the	54:56	the	54:56	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	7	22	theme	processing	1129:1138	arg1	method					1140:1145	the appropriate processing method	1113:1145	the appropriate processing method	1113:1145	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	0	23	theme	different	10:18	arg1	methods					31:37	different processing methods	10:37	different processing methods of hawthorn	10:49	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	6	24	theme	best	797:800	arg1	stability					802:810	the best stability	793:810	the best stability	793:810	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	7	25	theme	specific	1063:1070	arg1	properties					1072:1081	specific properties	1063:1081	specific properties	1063:1081	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	6	26	theme	CHP	864:866	arg1	properties					836:845	the emulsification properties	817:845	the emulsification properties of FHP, PHP, and CHP	817:866	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	7	27	theme	different	955:963	arg1	methods					976:982	different processing methods	955:982	different processing methods of hawthorn	955:994	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	1	28	theme	Charred	237:243	arg1	CH					257:258	CH	257:258	CH	257:258	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	28	theme	Charred	237:243	arg1	processing					245:254	Charred processing	237:254	Charred processing (CH)	237:259	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	7	29	theme	appropriate	1117:1127	arg1	method					1140:1145	the appropriate processing method	1113:1145	the appropriate processing method	1113:1145	In conclusion, our results showed that different processing methods of hawthorn affected the physicochemical properties of pectin, and pectin with specific properties could be obtained by choosing the appropriate processing method.					
36241293	5	30	theme	molecular	683:691	arg1	weight					693:698	molecular weight	683:698	molecular weight	683:698	PHP and CHP differ in galacturonic acid, molecular weight, and monosaccharide composition depending on the time of processing.					
36241293	0	31	theme	methods	31:37	arg1	Effect					0:5	Effect	0:5	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.	0:118	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	2	32	theme	methods	402:408	arg1	series					375:380	a series	373:380	a series of characterization methods	373:408	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	6	33	theme	emulsification	821:834	arg1	properties					836:845	the emulsification properties	817:845	the emulsification properties of FHP, PHP, and CHP	817:866	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	3	34	dep	lowest	494:499	arg1	g/mol					538:542	g/mol	538:542	g/mol	538:542	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	34	dep	lowest	494:499	arg1	73.67 × 103					525:535	73.67 × 103	525:535	73.67 × 103	525:535	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	34	dep	lowest	494:499	arg1	%					519:519	30.92 %	513:519	30.92 %	513:519	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	6	35	theme	HHP	785:787	arg1	emulsion					773:780	The emulsion	769:780	The emulsion of HHP	769:787	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	0	36	theme	hawthorn	42:49	arg1	methods					31:37	different processing methods	10:37	different processing methods of hawthorn	10:49	Effect of different processing methods of hawthorn on the properties and emulsification performance of hawthorn pectin.					
36241293	3	37	theme	molecular	461:469	arg1	weight					471:476	molecular weight	461:476	molecular weight	461:476	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	37	theme	molecular	461:469	arg1	esterification					442:455	esterification	442:455	esterification	442:455	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	37	theme	molecular	461:469	arg1	lowest					494:499	lowest	494:499	lowest	494:499	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	5	38	theme	processing	757:766	arg1	time					749:752	the time	745:752	the time of processing	745:766	PHP and CHP differ in galacturonic acid, molecular weight, and monosaccharide composition depending on the time of processing.					
36241293	6	39	contain	had	789:791	arg1	emulsion					773:780	The emulsion	769:780	The emulsion of HHP	769:787	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	6	39	contain	had	789:791	arg2	stability					802:810	the best stability	793:810	the best stability	793:810	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	6	40	theme	PHP	855:857	arg1	properties					836:845	the emulsification properties	817:845	the emulsification properties of FHP, PHP, and CHP	817:866	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	5	41	theme	galacturonic	664:675	arg1	acid					677:680	galacturonic acid	664:680	galacturonic acid	664:680	PHP and CHP differ in galacturonic acid, molecular weight, and monosaccharide composition depending on the time of processing.					
36241293	1	42	theme	vacuum	185:190	arg1	FH					207:208	FH	207:208	FH	207:208	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	42	theme	vacuum	185:190	arg1	freeze-drying					192:204	vacuum freeze-drying	185:204	vacuum freeze-drying (FH)	185:209	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	3	43	theme	BHP	481:483	arg1	weight					471:476	molecular weight	461:476	molecular weight	461:476	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	43	theme	BHP	481:483	arg1	lowest					494:499	lowest	494:499	lowest	494:499	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	3	43	theme	BHP	481:483	arg1	esterification					442:455	esterification	442:455	esterification	442:455	The results indicated that the esterification and molecular weight of BHP were the lowest, which were 30.92 % and 73.67 × 103 (g/mol), respectively.					
36241293	1	44	theme	hawthorns	134:142	arg1	types					125:129	Five types	120:129	Five types of hawthorns	120:142	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	45	theme	air	168:170	arg1	drying					172:177	hot air drying	164:177	hot air drying (HH)	164:182	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	1	45	theme	air	168:170	arg1	HH					180:181	HH	180:181	HH	180:181	Five types of hawthorns were obtained using hot air drying (HH), vacuum freeze-drying (FH), Parched processing (PH), Charred processing (CH), and blackening (BH).					
36241293	6	46	theme	FHP	850:852	arg1	properties					836:845	the emulsification properties	817:845	the emulsification properties of FHP, PHP, and CHP	817:866	The emulsion of HHP had the best stability, and the emulsification properties of FHP, PHP, and CHP also showed better performance compared to BHP.					
36241293	2	47	dep	pectins	297:303	arg1	CHP					321:323	CHP	321:323	CHP	321:323	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	2	47	dep	pectins	297:303	arg1	PHP					316:318	PHP	316:318	PHP	316:318	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	2	47	dep	pectins	297:303	arg1	FHP					311:313	FHP	311:313	FHP	311:313	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	2	47	dep	pectins	297:303	arg1	BHP					326:328	BHP	326:328	BHP	326:328	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36241293	2	47	dep	pectins	297:303	arg1	HHP					306:308	HHP	306:308	HHP	306:308	Five types of pectins (HHP, FHP, PHP, CHP, BHP) were extracted and characterized based on a series of characterization methods.					
36269163	6	0	used	used	1090:1093	arg2	RSM					1081:1083	RSM	1081:1083	RSM	1081:1083	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	6	0	used	used	1090:1093	arg2	methodology					1068:1078	response surface methodology	1051:1078	response surface methodology (RSM)	1051:1084	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	5	1	theme	variables	934:942	arg1	nature					920:925	The combinational nature	902:925	The combinational nature of the variables	902:942	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	1	2	theme	Hydrogel	178:185	arg1	candidates					211:220	promising candidates	201:220	promising candidates in cartilage tissue engineering	201:252	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	1	2	theme	Hydrogel	178:185	arg1	materials					187:195	Hydrogel materials	178:195	Hydrogel materials	178:195	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	1	3	theme	porous	275:280	arg1	environment					282:292	a 3D porous environment	270:292	a 3D porous environment for cell proliferation and the development of new cartilage tissue	270:359	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	5	4	theme	ranges	1014:1019	arg1	analysis					973:980	an exhaustive analysis	959:980	an exhaustive analysis of all reasonable concentration ranges	959:1019	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	5	4	theme	ranges	1014:1019	arg1	impractical					1030:1040	impractical	1030:1040	impractical	1030:1040	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	6	5	theme	acid	1194:1197	arg1	HAMA					1213:1216	HAMA	1213:1216	HAMA	1213:1216	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	6	5	theme	acid	1194:1197	arg1	methacryloyl					1199:1210	hyaluronic acid methacryloyl	1183:1210	hyaluronic acid methacryloyl (HAMA)	1183:1217	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	0	6	theme	mechanical	106:115	arg1	properties					131:140	mechanical and transport properties	106:140	properties	131:140	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	7	7	theme	hydrogel	1423:1430	arg1	membrane					1432:1439	the hydrogel membrane	1419:1439	the hydrogel membrane	1419:1439	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	7	8	theme	diffusion	1394:1402	arg1	coefficient					1404:1414	diffusion coefficient	1394:1414	diffusion coefficient	1394:1414	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	6	9	theme	transport	1255:1263	arg1	properties					1265:1274	both mechanical and transport properties	1235:1274	properties	1265:1274	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	3	10	theme	crosslinking	594:605	arg1	density					607:613	the crosslinking density	590:613	the crosslinking density	590:613	In photocrosslinkable hydrogels, both of these material properties can be tuned by changing the crosslinking density.					
36269163	6	11	theme	response	1051:1058	arg1	RSM					1081:1083	RSM	1081:1083	RSM	1081:1083	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	6	11	theme	response	1051:1058	arg1	methodology					1068:1078	response surface methodology	1051:1078	response surface methodology (RSM)	1051:1084	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	2	12	theme	transport	386:394	arg1	properties					396:405	Both the mechanical and transport properties	362:405	properties	396:405	Both the mechanical and transport properties of hydrogel scaffolds influence the ability of encapsulated cells to produce neocartilage.					
36269163	1	13	theme	cell	298:301	arg1	proliferation					303:315	cell proliferation	298:315	cell proliferation	298:315	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	0	14	theme	transport	121:129	arg1	properties					131:140	mechanical and transport properties	106:140	properties	131:140	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	6	15	theme	methacryloyl	1199:1210	arg1	hybrid					1140:1145	a hybrid	1138:1145	a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties	1138:1274	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	2	16	theme	encapsulated	454:465	arg1	cells					467:471	encapsulated cells	454:471	encapsulated cells	454:471	Both the mechanical and transport properties of hydrogel scaffolds influence the ability of encapsulated cells to produce neocartilage.					
36269163	5	17	theme	exhaustive	962:971	arg1	analysis					973:980	an exhaustive analysis	959:980	an exhaustive analysis of all reasonable concentration ranges	959:1019	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	5	17	theme	exhaustive	962:971	arg1	impractical					1030:1040	impractical	1030:1040	impractical	1030:1040	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	8	18	used	used	1507:1510	arg2	models					1459:1464	Two mathematical models	1442:1464	Two mathematical models	1442:1464	Two mathematical models were fitted to the experimental data and used to predict the optimum hydrogel composition.					
36269163	4	19	theme	interdependent	629:642	arg1	nature					644:649	the interdependent nature	625:649	the interdependent nature of the structural, physical and biological properties of photocrosslinkable	625:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	4	20	theme	physiochemical	854:867	arg1	characterization					884:899	physiochemical and biological characterization	854:899	physiochemical and biological characterization	854:899	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	1	21	theme	promising	201:209	arg1	candidates					211:220	promising candidates	201:220	promising candidates in cartilage tissue engineering	201:252	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	1	21	theme	promising	201:209	arg1	materials					187:195	Hydrogel materials	178:195	Hydrogel materials	178:195	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	5	22	theme	combinational	906:918	arg1	nature					920:925	The combinational nature	902:925	The combinational nature of the variables	902:942	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	6	23	theme	hyaluronic	1183:1192	arg1	acid					1194:1197	hyaluronic acid	1183:1197	hyaluronic acid methacryloyl (HAMA)	1183:1217	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	7	24	theme	photoinitiator	1340:1353	arg1	concentration					1355:1367	photoinitiator concentration	1340:1367	photoinitiator concentration	1340:1367	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	4	25	theme	sequential	817:826	arg1	steps					845:849	sequential and/or iterative steps	817:849	sequential and/or iterative steps of physiochemical and biological characterization	817:899	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	2	26	theme	scaffolds	419:427	arg1	mechanical					371:380	mechanical	371:380	mechanical	371:380	Both the mechanical and transport properties of hydrogel scaffolds influence the ability of encapsulated cells to produce neocartilage.					
36269163	2	27	theme	hydrogel	410:417	arg1	scaffolds					419:427	hydrogel scaffolds	410:427	hydrogel scaffolds	410:427	Both the mechanical and transport properties of hydrogel scaffolds influence the ability of encapsulated cells to produce neocartilage.					
36269163	4	28	theme	iterative	835:843	arg1	steps					845:849	sequential and/or iterative steps	817:849	sequential and/or iterative steps of physiochemical and biological characterization	817:899	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	1	29	theme	cartilage	225:233	arg1	engineering					242:252	cartilage tissue engineering	225:252	cartilage tissue engineering	225:252	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	9	30	theme	optimal	1570:1576	arg1	composition					1578:1588	the optimal composition	1566:1588	the optimal composition	1566:1588	Finally, the optimal composition was tested and compared with the predicted values.					
36269163	7	31	theme	HAMA	1330:1333	arg1	effect					1313:1318	the effect	1309:1318	the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane	1309:1439	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	1	32	theme	tissue	235:240	arg1	engineering					242:252	cartilage tissue engineering	225:252	cartilage tissue engineering	225:252	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	0	33	theme	methacryloyl	38:49	arg1	composition					15:25	the composition	11:25	the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology	11:175	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	7	34	theme	shear	1376:1380	arg1	modulus					1382:1388	shear modulus	1376:1388	shear modulus	1376:1388	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	0	35	theme	surface	157:163	arg1	methodology					165:175	response surface methodology	148:175	response surface methodology	148:175	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	8	36	theme	hydrogel	1535:1542	arg1	composition					1544:1554	the optimum hydrogel composition	1523:1554	the optimum hydrogel composition	1523:1554	Two mathematical models were fitted to the experimental data and used to predict the optimum hydrogel composition.					
36269163	9	37	theme	predicted	1623:1631	arg1	values					1633:1638	the predicted values	1619:1638	the predicted values	1619:1638	Finally, the optimal composition was tested and compared with the predicted values.					
36269163	0	38	theme	gelatin	30:36	arg1	methacryloyl					38:49	gelatin methacryloyl	30:49	gelatin methacryloyl	30:49	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	0	39	theme	response	148:155	arg1	methodology					165:175	response surface methodology	148:175	response surface methodology	148:175	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	8	40	theme	experimental	1485:1496	arg1	data					1498:1501	the experimental data	1481:1501	the experimental data	1481:1501	Two mathematical models were fitted to the experimental data and used to predict the optimum hydrogel composition.					
36269163	6	41	theme	gelatin-methacryloyl	1150:1169	arg1	hybrid					1140:1145	a hybrid	1138:1145	a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties	1138:1274	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	3	42	theme	photocrosslinkable	501:518	arg1	hydrogels					520:528	photocrosslinkable hydrogels	501:528	photocrosslinkable hydrogels	501:528	In photocrosslinkable hydrogels, both of these material properties can be tuned by changing the crosslinking density.					
36269163	0	43	theme	hyaluronic	55:64	arg1	acid					66:69	hyaluronic acid	55:69	hyaluronic acid	55:69	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	1	44	theme	new	340:342	arg1	tissue					354:359	new cartilage tissue	340:359	new cartilage tissue	340:359	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	6	45	theme	hybrid	1140:1145	arg1	composition					1123:1133	the composition	1119:1133	the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties	1119:1274	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	0	46	dep	methacryloyl	38:49	arg1	hydrogels					84:92	methacryloyl hydrogels	71:92	methacryloyl hydrogels	71:92	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	4	47	theme	complicated	786:796	arg1	process					798:804	a complicated process	784:804	a complicated process	784:804	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	4	47	theme	complicated	786:796	arg1	composition					759:769	optimizing composition	748:769	optimizing composition	748:769	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	1	48	theme	cartilage	344:352	arg1	tissue					354:359	new cartilage tissue	340:359	new cartilage tissue	340:359	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	7	49	theme	GelMA	1323:1327	arg1	effect					1313:1318	the effect	1309:1318	the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane	1309:1439	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	7	50	from	effect	1313:1318	arg1	modulus					1382:1388	shear modulus	1376:1388	shear modulus	1376:1388	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	7	50	from	effect	1313:1318	arg1	coefficient					1404:1414	diffusion coefficient	1394:1414	diffusion coefficient	1394:1414	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	7	51	theme	membrane	1432:1439	arg1	modulus					1382:1388	shear modulus	1376:1388	shear modulus	1376:1388	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	7	51	theme	membrane	1432:1439	arg1	coefficient					1404:1414	diffusion coefficient	1394:1414	diffusion coefficient	1394:1414	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	3	52	theme	material	545:552	arg1	properties					554:563	these material properties	539:563	these material properties	539:563	In photocrosslinkable hydrogels, both of these material properties can be tuned by changing the crosslinking density.					
36269163	1	53	theme	tissue	354:359	arg1	proliferation					303:315	cell proliferation	298:315	cell proliferation	298:315	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	1	53	theme	tissue	354:359	arg1	development					325:335	the development	321:335	the development of new cartilage tissue	321:359	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	7	54	dep	modulus	1382:1388	arg1	the					1372:1374	the	1372:1374	the	1372:1374	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	4	55	theme	characterization	884:899	arg1	steps					845:849	sequential and/or iterative steps	817:849	sequential and/or iterative steps of physiochemical and biological characterization	817:899	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	7	56	theme	concentration	1355:1367	arg1	effect					1313:1318	the effect	1309:1318	the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane	1309:1439	RSM was employed to investigate the effect of GelMA, HAMA, and photoinitiator concentration on the shear modulus and diffusion coefficient of the hydrogel membrane.					
36269163	6	57	theme	mechanical	1240:1249	arg1	properties					1265:1274	both mechanical and transport properties	1235:1274	properties	1265:1274	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	4	58	theme	structural	658:667	arg1	properties					694:703	the structural, physical and biological properties	654:703	the structural, physical and biological properties of photocrosslinkable	654:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	8	59	theme	mathematical	1446:1457	arg1	models					1459:1464	Two mathematical models	1442:1464	Two mathematical models	1442:1464	Two mathematical models were fitted to the experimental data and used to predict the optimum hydrogel composition.					
36269163	4	60	theme	biological	873:882	arg1	characterization					884:899	physiochemical and biological characterization	854:899	physiochemical and biological characterization	854:899	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	1	61	from	candidates	211:220	arg1	engineering					242:252	cartilage tissue engineering	225:252	cartilage tissue engineering	225:252	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
36269163	5	62	theme	concentration	1000:1012	arg1	ranges					1014:1019	all reasonable concentration ranges	985:1019	all reasonable concentration ranges	985:1019	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	0	63	theme	methacryloyl	71:82	arg1	hydrogels					84:92	methacryloyl hydrogels	71:92	methacryloyl hydrogels	71:92	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	4	64	theme	properties	694:703	arg1	nature					644:649	the interdependent nature	625:649	the interdependent nature of the structural, physical and biological properties of photocrosslinkable	625:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	8	65	theme	optimum	1527:1533	arg1	composition					1544:1554	the optimum hydrogel composition	1523:1554	the optimum hydrogel composition	1523:1554	Two mathematical models were fitted to the experimental data and used to predict the optimum hydrogel composition.					
36269163	2	66	theme	cells	467:471	arg1	ability					443:449	the ability	439:449	the ability of encapsulated cells to produce neocartilage	439:495	Both the mechanical and transport properties of hydrogel scaffolds influence the ability of encapsulated cells to produce neocartilage.					
36269163	5	67	theme	reasonable	989:998	arg1	ranges					1014:1019	all reasonable concentration ranges	985:1019	all reasonable concentration ranges	985:1019	The combinational nature of the variables indicates that an exhaustive analysis of all reasonable concentration ranges would be impractical.					
36269163	4	68	theme	photocrosslinkable	708:725	arg1	properties					694:703	the structural, physical and biological properties	654:703	the structural, physical and biological properties of photocrosslinkable	654:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	4	69	theme	physical	670:677	arg1	properties					694:703	the structural, physical and biological properties	654:703	the structural, physical and biological properties of photocrosslinkable	654:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	0	70	theme	acid	66:69	arg1	composition					15:25	the composition	11:25	the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology	11:175	Optimizing the composition of gelatin methacryloyl and hyaluronic acid methacryloyl hydrogels to maximize mechanical and transport properties using response surface methodology.					
36269163	4	71	theme	biological	683:692	arg1	properties					694:703	the structural, physical and biological properties	654:703	the structural, physical and biological properties of photocrosslinkable	654:725	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	4	72	theme	optimizing	748:757	arg1	process					798:804	a complicated process	784:804	a complicated process	784:804	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	4	72	theme	optimizing	748:757	arg1	composition					759:769	optimizing composition	748:769	optimizing composition	748:769	However, the interdependent nature of the structural, physical and biological properties of photocrosslinkable hydrogels means that optimizing composition is typically a complicated process, involving sequential and/or iterative steps of physiochemical and biological characterization.					
36269163	6	73	theme	surface	1060:1066	arg1	RSM					1081:1083	RSM	1081:1083	RSM	1081:1083	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	6	73	theme	surface	1060:1066	arg1	methodology					1068:1078	response surface methodology	1051:1078	response surface methodology (RSM)	1051:1084	Herein, response surface methodology (RSM) was used to efficiently optimize the composition of a hybrid of gelatin-methacryloyl (GelMA) and hyaluronic acid methacryloyl (HAMA) with respect to both mechanical and transport properties.					
36269163	1	74	theme	3D	272:273	arg1	environment					282:292	a 3D porous environment	270:292	a 3D porous environment for cell proliferation and the development of new cartilage tissue	270:359	Hydrogel materials are promising candidates in cartilage tissue engineering as they provide a 3D porous environment for cell proliferation and the development of new cartilage tissue.					
37105305	2	0	theme	adsorptive	496:505	arg1	sites					507:511	numerous adsorptive sites	487:511	numerous adsorptive sites	487:511	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	7	1	theme	electrostatic	1188:1200	arg1	interaction					1202:1212	electrostatic interaction	1188:1212	electrostatic interaction	1188:1212	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	0	2	theme	uranium	88:94	arg1	capture					100:106	uranium(VI) capture	88:106	uranium(VI) capture from wastewater	88:122	Magnetite/β-cyclodextrin/fly ash composite as an effective and recyclable adsorbent for uranium(VI) capture from wastewater.					
37105305	4	3	theme	removal	844:850	arg1	process					852:858	the uranium(VI) removal process	828:858	the uranium(VI) removal process	828:858	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	7	4	theme	interaction	1202:1212	arg1	synergism					1119:1127	the synergism	1115:1127	the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction	1115:1212	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	6	5	theme	uranium	985:991	arg1	higher					1024:1029	higher	1024:1029	higher	1024:1029	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	6	5	theme	uranium	985:991	arg1	rate					977:980	the removal rate	965:980	the removal rate of uranium(VI) on Fe3O4/β-CD/FA	965:1012	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	2	6	theme	uranium	532:538	arg1	removal					521:527	the removal	517:527	the removal of uranium	517:538	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	1	7	dep	prepared	266:273	arg1	VI					176:177	VI	176:177	VI	176:177	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	2	8	dep	providing	477:485	arg1	VI					540:541	VI	540:541	VI	540:541	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	8	9	dep	efficacious	1270:1280	arg1	an					1267:1268	an	1267:1268	an	1267:1268	Given the above, Fe3O4/β-CD/FA would be regarded as an efficacious, green and promising adsorbent for uranium(VI) separation from wastewater.					
37105305	7	10	theme	reaction	1156:1163	arg1	synergism					1119:1127	the synergism	1115:1127	the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction	1115:1212	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	0	11	dep	capture	100:106	arg1	VI					96:97	VI	96:97	VI	96:97	Magnetite/β-cyclodextrin/fly ash composite as an effective and recyclable adsorbent for uranium(VI) capture from wastewater.					
37105305	7	12	theme	reaction	1138:1145	arg1	synergism					1119:1127	the synergism	1115:1127	the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction	1115:1212	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	7	13	theme	uranium	1063:1069	arg1	immobilization					1045:1058	The immobilization	1041:1058	The immobilization of uranium(VI) on Fe3O4/β-CD/FA	1041:1090	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	4	14	theme	experimental	761:772	arg1	data					774:777	the experimental data	757:777	the experimental data	757:777	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	8	15	from	wastewater	1345:1354	arg1	separation					1329:1338	uranium(VI) separation	1317:1338	uranium(VI) separation from wastewater	1317:1354	Given the above, Fe3O4/β-CD/FA would be regarded as an efficacious, green and promising adsorbent for uranium(VI) separation from wastewater.					
37105305	4	16	theme	uranium	832:838	arg1	process					852:858	the uranium(VI) removal process	828:858	the uranium(VI) removal process	828:858	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	6	17	dep	higher	1024:1029	arg1	%					1038:1038	90.4%	1034:1038	90.4%	1034:1038	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	6	17	dep	higher	1024:1029	arg1	to					1031:1032	to	1031:1032	to	1031:1032	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	2	18	theme	oxygen-containing	440:456	arg1	groups					469:474	abundant oxygen-containing functional groups	431:474	abundant oxygen-containing functional groups	431:474	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	2	19	theme	numerous	487:494	arg1	sites					507:511	numerous adsorptive sites	487:511	numerous adsorptive sites	487:511	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	7	20	theme	chemical	1166:1173	arg1	reaction					1175:1182	chemical reaction	1166:1182	chemical reaction	1166:1182	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	7	21	from	immobilization	1045:1058	arg1	Fe3O4/β-CD/FA					1078:1090	Fe3O4/β-CD/FA	1078:1090	Fe3O4/β-CD/FA	1078:1090	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	4	22	theme	Langmuir	722:729	arg1	models					731:736	Langmuir models	722:736	Langmuir models	722:736	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	1	23	theme	uranium	168:174	arg1	separation					154:163	the separation	150:163	the separation of uranium	150:174	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	2	24	theme	abundant	431:438	arg1	groups					469:474	abundant oxygen-containing functional groups	431:474	abundant oxygen-containing functional groups	431:474	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	6	25	theme	removal	969:975	arg1	higher					1024:1029	higher	1024:1029	higher	1024:1029	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	6	25	theme	removal	969:975	arg1	rate					977:980	the removal rate	965:980	the removal rate of uranium(VI) on Fe3O4/β-CD/FA	965:1012	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	8	26	theme	uranium	1317:1323	arg1	separation					1329:1338	uranium(VI) separation	1317:1338	uranium(VI) separation from wastewater	1317:1354	Given the above, Fe3O4/β-CD/FA would be regarded as an efficacious, green and promising adsorbent for uranium(VI) separation from wastewater.					
37105305	8	27	dep	separation	1329:1338	arg1	VI					1325:1326	VI	1325:1326	VI	1325:1326	Given the above, Fe3O4/β-CD/FA would be regarded as an efficacious, green and promising adsorbent for uranium(VI) separation from wastewater.					
37105305	7	28	theme	complex	1148:1154	arg1	reaction					1156:1163	complex reaction	1148:1163	complex reaction	1148:1163	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	7	29	theme	redox	1132:1136	arg1	reaction					1138:1145	redox reaction	1132:1145	redox reaction	1132:1145	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	3	30	theme	maximum	576:582	arg1	efficiency					604:613	the maximum uranium(VI) removal efficiency	572:613	the maximum uranium(VI) removal efficiency	572:613	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	30	theme	maximum	576:582	arg1	higher					650:655	higher	650:655	higher	650:655	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	1	31	theme	chemical	281:288	arg1	technology					306:315	a chemical coprecipitation technology	279:315	a chemical coprecipitation technology	279:315	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	3	32	theme	uranium	584:590	arg1	efficiency					604:613	the maximum uranium(VI) removal efficiency	572:613	the maximum uranium(VI) removal efficiency	572:613	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	32	theme	uranium	584:590	arg1	higher					650:655	higher	650:655	higher	650:655	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	4	33	dep	process	852:858	arg1	VI					840:841	VI	840:841	VI	840:841	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	1	34	theme	coprecipitation	290:304	arg1	technology					306:315	a chemical coprecipitation technology	279:315	a chemical coprecipitation technology	279:315	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	0	35	dep	effective	49:57	arg1	adsorbent					74:82	adsorbent	74:82	adsorbent	74:82	Magnetite/β-cyclodextrin/fly ash composite as an effective and recyclable adsorbent for uranium(VI) capture from wastewater.					
37105305	5	36	theme	good	895:898	arg1	ability					918:924	good anti-interference ability	895:924	good anti-interference ability	895:924	In addition, Fe3O4/β-CD/FA showed good anti-interference ability and recoverability.					
37105305	2	37	theme	functional	458:467	arg1	groups					469:474	abundant oxygen-containing functional groups	431:474	abundant oxygen-containing functional groups	431:474	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	6	38	dep	uranium	985:991	arg1	VI					993:994	VI	993:994	VI	993:994	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	6	39	from	rate	977:980	arg1	Fe3O4/β-CD/FA					1000:1012	Fe3O4/β-CD/FA	1000:1012	Fe3O4/β-CD/FA	1000:1012	After five cycles, the removal rate of uranium(VI) on Fe3O4/β-CD/FA was still higher to 90.4%.					
37105305	5	40	theme	anti-interference	900:916	arg1	ability					918:924	good anti-interference ability	895:924	good anti-interference ability	895:924	In addition, Fe3O4/β-CD/FA showed good anti-interference ability and recoverability.					
37105305	4	41	theme	chemical	798:805	arg1	adsorption					807:816	chemical adsorption	798:816	chemical adsorption	798:816	Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process.					
37105305	2	42	theme	characterization	322:337	arg1	results					339:345	The characterization results	318:345	The characterization results	318:345	The characterization results indicated that Fe3O4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI).					
37105305	3	43	dep	efficiency	604:613	arg1	VI					592:593	VI	592:593	VI	592:593	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	44	theme	Fe3O4/β-CD/FA	631:643	arg1	capacity					619:626	capacity	619:626	capacity	619:626	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	44	theme	Fe3O4/β-CD/FA	631:643	arg1	efficiency					604:613	the maximum uranium(VI) removal efficiency	572:613	the maximum uranium(VI) removal efficiency	572:613	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	44	theme	Fe3O4/β-CD/FA	631:643	arg1	higher					650:655	higher	650:655	higher	650:655	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	45	theme	removal	596:602	arg1	efficiency					604:613	the maximum uranium(VI) removal efficiency	572:613	the maximum uranium(VI) removal efficiency	572:613	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	3	45	theme	removal	596:602	arg1	higher					650:655	higher	650:655	higher	650:655	At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe3O4/β-CD/FA were higher to 97.8% and 444.4 mg g-1, respectively.					
37105305	1	46	theme	Magnetite/β-cyclodextrin/fly	197:224	arg1	Fe3O4/β-CD/FA					241:253	Fe3O4/β-CD/FA	241:253	Fe3O4/β-CD/FA	241:253	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	1	46	theme	Magnetite/β-cyclodextrin/fly	197:224	arg1	composite					230:238	Magnetite/β-cyclodextrin/fly ash composite	197:238	Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA)	197:254	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	1	46	theme	Magnetite/β-cyclodextrin/fly	197:224	arg1	adsorbent					136:144	adsorbent	136:144	adsorbent	136:144	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	7	47	theme	reaction	1175:1182	arg1	synergism					1119:1127	the synergism	1115:1127	the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction	1115:1212	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	1	48	theme	ash	226:228	arg1	Fe3O4/β-CD/FA					241:253	Fe3O4/β-CD/FA	241:253	Fe3O4/β-CD/FA	241:253	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	1	48	theme	ash	226:228	arg1	composite					230:238	Magnetite/β-cyclodextrin/fly ash composite	197:238	Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA)	197:254	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	1	48	theme	ash	226:228	arg1	adsorbent					136:144	adsorbent	136:144	adsorbent	136:144	As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe3O4/β-CD/FA) was first prepared via a chemical coprecipitation technology.					
37105305	7	49	dep	uranium	1063:1069	arg1	VI					1071:1072	VI	1071:1072	VI	1071:1072	The immobilization of uranium(VI) on Fe3O4/β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction.					
37105305	0	50	from	wastewater	113:122	arg1	capture					100:106	uranium(VI) capture	88:106	uranium(VI) capture from wastewater	88:122	Magnetite/β-cyclodextrin/fly ash composite as an effective and recyclable adsorbent for uranium(VI) capture from wastewater.					
37011753	4	0	theme	adsorption	691:700	arg1	process					702:708	the adsorption process	687:708	the adsorption process	687:708	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	6	1	theme	calculated	1037:1046	arg1	parameters					1062:1071	The calculated thermodynamic parameters	1033:1071	The calculated thermodynamic parameters	1033:1071	The calculated thermodynamic parameters indicate that MB adsorption on SA-SiO2-PAMPS is spontaneous and endothermic.					
37011753	2	2	theme	2-acrylamido-2-methylpropane	341:368	arg1	poly					336:339	poly	336:339	poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS)	336:391	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
37011753	2	2	theme	2-acrylamido-2-methylpropane	341:368	arg1	acid					379:382	2-acrylamido-2-methylpropane sulfonic acid	341:382	2-acrylamido-2-methylpropane sulfonic acid	341:382	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
37011753	0	3	theme	blue	84:87	arg1	methylene					74:82	methylene blue	74:87	methylene blue	74:87	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	1	4	theme	reported	157:164	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	3	5	theme	material	520:527	arg1	SA-SiO2-PAMPS					529:541	the obtained composite material SA-SiO2-PAMPS	497:541	the obtained composite material SA-SiO2-PAMPS	497:541	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	6	theme	excellent	549:557	arg1	capacity					570:577	excellent adsorption capacity	549:577	excellent adsorption capacity toward cationic dye methylene blue (MB)	549:617	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	7	theme	water	250:254	arg1	contaminants					256:267	water contaminants	250:267	water contaminants	250:267	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	3	8	theme	adsorption	559:568	arg1	capacity					570:577	excellent adsorption capacity	549:577	excellent adsorption capacity toward cationic dye methylene blue (MB)	549:617	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	4	9	theme	Langmuir	764:771	arg1	model					782:786	Langmuir isotherm model	764:786	Langmuir isotherm model	764:786	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	1	10	from	sites	139:143	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	3	11	theme	sulfonate	479:487	arg1	groups					489:494	abundant sulfonate groups	470:494	abundant sulfonate groups	470:494	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	12	theme	contaminants	256:267	arg1	adsorption					236:245	adsorption	236:245	adsorption of water contaminants	236:267	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	4	13	theme	monolayer	855:863	arg1	behavior					876:883	monolayer adsorption behavior	855:883	monolayer adsorption behavior	855:883	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	4	14	theme	kinetic	746:752	arg1	model					754:758	pseudo-second-order kinetic model	726:758	pseudo-second-order kinetic model	726:758	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	3	15	theme	obtained	501:508	arg1	SA-SiO2-PAMPS					529:541	the obtained composite material SA-SiO2-PAMPS	497:541	the obtained composite material SA-SiO2-PAMPS	497:541	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	16	theme	sodium	166:171	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	5	17	theme	Langmuir	932:939	arg1	model					941:945	Langmuir model	932:945	Langmuir model	932:945	The maximum adsorption capacity obtained from Langmuir model is found to be 427.36, 495.05, and 564.97 mg/g under 25, 35, and 45 °C, respectively.					
37011753	3	18	theme	composite	510:518	arg1	SA-SiO2-PAMPS					529:541	the obtained composite material SA-SiO2-PAMPS	497:541	the obtained composite material SA-SiO2-PAMPS	497:541	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	19	theme	alginate	173:180	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	0	20	theme	sodium	12:17	arg1	beads					43:47	sodium alginate-SiO2 composite beads	12:47	sodium alginate-SiO2 composite beads	12:47	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	4	21	theme	behavior	876:883	arg1	existence					818:826	the existence	814:826	the existence of chemical adsorption and monolayer adsorption behavior	814:883	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	2	22	theme	SA-SiO2	302:308	arg1	beads					310:314	porous SA-SiO2 beads	295:314	porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS)	295:391	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
37011753	5	23	theme	maximum	890:896	arg1	capacity					909:916	The maximum adsorption capacity	886:916	The maximum adsorption capacity obtained from Langmuir model	886:945	The maximum adsorption capacity obtained from Langmuir model is found to be 427.36, 495.05, and 564.97 mg/g under 25, 35, and 45 °C, respectively.					
37011753	5	23	theme	maximum	890:896	arg1	427.36					962:967	427.36	962:967	427.36	962:967	The maximum adsorption capacity obtained from Langmuir model is found to be 427.36, 495.05, and 564.97 mg/g under 25, 35, and 45 °C, respectively.					
37011753	4	24	theme	adsorption	865:874	arg1	behavior					876:883	monolayer adsorption behavior	855:883	monolayer adsorption behavior	855:883	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	2	25	theme	porous	295:300	arg1	beads					310:314	porous SA-SiO2 beads	295:314	porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS)	295:391	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
37011753	1	26	theme	SA	183:184	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	0	27	theme	composite	33:41	arg1	beads					43:47	sodium alginate-SiO2 composite beads	12:47	sodium alginate-SiO2 composite beads	12:47	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	4	28	theme	pseudo-second-order	726:744	arg1	model					754:758	pseudo-second-order kinetic model	726:758	pseudo-second-order kinetic model	726:758	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	4	29	theme	chemical	831:838	arg1	adsorption					840:849	chemical adsorption	831:849	chemical adsorption	831:849	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	6	30	theme	thermodynamic	1048:1060	arg1	parameters					1062:1071	The calculated thermodynamic parameters	1033:1071	The calculated thermodynamic parameters	1033:1071	The calculated thermodynamic parameters indicate that MB adsorption on SA-SiO2-PAMPS is spontaneous and endothermic.					
37011753	0	31	theme	alginate-SiO2	19:31	arg1	beads					43:47	sodium alginate-SiO2 composite beads	12:47	sodium alginate-SiO2 composite beads	12:47	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	3	32	theme	groups	489:494	arg1	properties					438:447	the porous properties	427:447	the porous properties	427:447	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	32	theme	groups	489:494	arg1	existence					457:465	the existence	453:465	the existence of abundant sulfonate groups	453:494	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	33	theme	-based	186:191	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	3	34	theme	abundant	470:477	arg1	groups					489:494	abundant sulfonate groups	470:494	abundant sulfonate groups	470:494	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	35	theme	dye	595:597	arg1	methylene					599:607	cationic dye methylene blue	586:612	cationic dye methylene blue (MB)	586:617	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	35	theme	dye	595:597	arg1	MB					615:616	MB	615:616	MB	615:616	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	4	36	theme	isotherm	658:665	arg1	studies					667:673	The adsorption kinetic and adsorption isotherm studies	620:673	studies	667:673	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	1	37	theme	porous	193:198	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	4	38	theme	adsorption	647:656	arg1	studies					667:673	The adsorption kinetic and adsorption isotherm studies	620:673	studies	667:673	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	6	39	theme	MB	1087:1088	arg1	adsorption					1090:1099	MB adsorption	1087:1099	MB adsorption on SA-SiO2-PAMPS	1087:1116	The calculated thermodynamic parameters indicate that MB adsorption on SA-SiO2-PAMPS is spontaneous and endothermic.					
37011753	3	40	theme	porous	431:436	arg1	properties					438:447	the porous properties	427:447	the porous properties	427:447	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	4	41	theme	adsorption	840:849	arg1	existence					818:826	the existence	814:826	the existence of chemical adsorption and monolayer adsorption behavior	814:883	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	1	42	from	beads	200:204	arg1	lack					105:108	The lack	101:108	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads	101:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	0	43	theme	efficient	53:61	arg1	removal					63:69	efficient removal	53:69	efficient removal of methylene blue from water	53:98	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	3	44	theme	cationic	586:593	arg1	methylene					599:607	cationic dye methylene blue	586:612	cationic dye methylene blue (MB)	586:617	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	44	theme	cationic	586:593	arg1	MB					615:616	MB	615:616	MB	615:616	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	1	45	theme	sufficient	113:122	arg1	sites					139:143	sufficient active binding sites	113:143	sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads	113:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	5	46	theme	adsorption	898:907	arg1	capacity					909:916	The maximum adsorption capacity	886:916	The maximum adsorption capacity obtained from Langmuir model	886:945	The maximum adsorption capacity obtained from Langmuir model is found to be 427.36, 495.05, and 564.97 mg/g under 25, 35, and 45 °C, respectively.					
37011753	5	46	theme	adsorption	898:907	arg1	427.36					962:967	427.36	962:967	427.36	962:967	The maximum adsorption capacity obtained from Langmuir model is found to be 427.36, 495.05, and 564.97 mg/g under 25, 35, and 45 °C, respectively.					
37011753	1	47	theme	active	124:129	arg1	sites					139:143	sufficient active binding sites	113:143	sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads	113:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	1	48	from	lack	105:108	arg1	beads					200:204	commonly reported sodium alginate (SA)-based porous beads	148:204	commonly reported sodium alginate (SA)-based porous beads	148:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	4	49	theme	isotherm	773:780	arg1	model					782:786	Langmuir isotherm model	764:786	Langmuir isotherm model	764:786	The adsorption kinetic and adsorption isotherm studies reveal that the adsorption process fits closely to pseudo-second-order kinetic model and Langmuir isotherm model, respectively, suggesting the existence of chemical adsorption and monolayer adsorption behavior.					
37011753	1	50	theme	binding	131:137	arg1	sites					139:143	sufficient active binding sites	113:143	sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads	113:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	0	51	theme	methylene	74:82	arg1	removal					63:69	efficient removal	53:69	efficient removal of methylene blue from water	53:98	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	0	52	from	water	94:98	arg1	removal					63:69	efficient removal	53:69	efficient removal of methylene blue from water	53:98	Engineering sodium alginate-SiO2 composite beads for efficient removal of methylene blue from water.					
37011753	3	53	theme	blue	609:612	arg1	methylene					599:607	cationic dye methylene blue	586:612	cationic dye methylene blue (MB)	586:617	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	3	53	theme	blue	609:612	arg1	MB					615:616	MB	615:616	MB	615:616	Due to the porous properties and the existence of abundant sulfonate groups, the obtained composite material SA-SiO2-PAMPS shows excellent adsorption capacity toward cationic dye methylene blue (MB).					
37011753	6	54	from	adsorption	1090:1099	arg1	SA-SiO2-PAMPS					1104:1116	SA-SiO2-PAMPS	1104:1116	SA-SiO2-PAMPS	1104:1116	The calculated thermodynamic parameters indicate that MB adsorption on SA-SiO2-PAMPS is spontaneous and endothermic.					
37011753	1	55	theme	sites	139:143	arg1	lack					105:108	The lack	101:108	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads	101:204	The lack of sufficient active binding sites in commonly reported sodium alginate (SA)-based porous beads hampers their performances in adsorption of water contaminants.					
37011753	2	56	theme	sulfonic	370:377	arg1	poly					336:339	poly	336:339	poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS)	336:391	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
37011753	2	56	theme	sulfonic	370:377	arg1	acid					379:382	2-acrylamido-2-methylpropane sulfonic acid	341:382	2-acrylamido-2-methylpropane sulfonic acid	341:382	To address this problem, porous SA-SiO2 beads functionalized with poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS) are reported in this work.					
36674522	7	0	theme	new	1077:1079	arg1	characteristics					1092:1106	new mechanical characteristics	1077:1106	new mechanical characteristics that are advantageous in terms of strength	1077:1149	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	9	1	theme	strength	1435:1442	arg1	terms					1415:1419	terms	1415:1419	terms of mechanical strength	1415:1442	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	4	2	theme	waste	483:487	arg1	materials					489:497	waste materials	483:497	waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride	483:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	7	3	theme	mechanical	1081:1090	arg1	characteristics					1092:1106	new mechanical characteristics	1077:1106	new mechanical characteristics that are advantageous in terms of strength	1077:1149	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	10	4	theme	functional	1557:1566	arg1	characteristics					1568:1582	its functional characteristics	1553:1582	its functional characteristics for at least 1 month	1553:1603	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
36674522	1	5	theme	sustainable	180:190	arg1	economy					202:208	the sustainable and green economy	176:208	the sustainable and green economy	176:208	The need for new non-animal and non-petroleum-based materials is strongly emphasized in the sustainable and green economy.					
36674522	4	6	with	cactus	504:509	arg1	polymers					552:559	polymers	552:559	polymers like polyurethane or polyvinyl chloride	552:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	10	7	theme	material	1482:1489	arg1	application					1455:1465	the application	1451:1465	the application of the created material as a card folder	1451:1506	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
36674522	7	8	from	advantageous	1117:1128	arg1	terms					1133:1137	terms	1133:1137	terms of strength	1133:1149	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	4	9	from	composites	469:478	arg1	practice					443:450	practice	443:450	practice	443:450	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	7	10	theme	apple	919:923	arg1	powder					925:930	apple powder	919:930	apple powder	919:930	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	9	11	theme	powder	1267:1272	arg1	amounts					1250:1256	Different amounts	1240:1256	Different amounts of apple powder	1240:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	11	theme	powder	1267:1272	arg1	powder					1267:1272	apple powder	1261:1272	apple powder	1261:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	10	12	theme	card	1496:1499	arg1	folder					1501:1506	a card folder	1494:1506	a card folder	1494:1506	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
36674522	9	13	dep	60	1326:1327	arg1	to					1323:1324	to	1323:1324	to	1323:1324	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	10	14	from	durable	1526:1532	arg1	use					1537:1539	use	1537:1539	use	1537:1539	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
36674522	5	15	theme	natural	691:697	arg1	materials					718:726	natural, biodegradable raw materials	691:726	natural, biodegradable raw materials	691:726	The article presents the results of work aimed at obtaining a material based entirely on natural, biodegradable raw materials.					
36674522	7	16	from	terms	1133:1137	arg1	advantageous					1117:1128	advantageous	1117:1128	advantageous	1117:1128	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	9	17	theme	powder	1382:1387	arg1	%					1372:1372	40%	1370:1372	40% of this powder	1370:1387	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	17	theme	powder	1382:1387	arg1	powder					1382:1387	this powder	1377:1387	this powder	1377:1387	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	18	from	favorable	1402:1410	arg1	terms					1415:1419	terms	1415:1419	terms of mechanical strength	1415:1442	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	8	19	theme	powder	1189:1194	arg1	layer					1196:1200	the apple powder layer	1179:1200	the apple powder layer	1179:1200	Microscopic observation of the apple powder layer showed that the coverage was uniform.					
36674522	7	20	theme	resulting	1049:1057	arg1	material					1059:1066	The resulting material	1045:1066	The resulting material acquired new mechanical characteristics that are advantageous in terms of strength	1045:1149	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	4	21	with	pineapples	512:521	arg1	polymers					552:559	polymers	552:559	polymers like polyurethane or polyvinyl chloride	552:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	1	22	theme	green	196:200	arg1	economy					202:208	the sustainable and green economy	176:208	the sustainable and green economy	176:208	The need for new non-animal and non-petroleum-based materials is strongly emphasized in the sustainable and green economy.					
36674522	8	23	theme	Microscopic	1152:1162	arg1	observation					1164:1174	Microscopic observation	1152:1174	Microscopic observation of the apple powder layer	1152:1200	Microscopic observation of the apple powder layer showed that the coverage was uniform.					
36674522	9	24	theme	Different	1240:1248	arg1	amounts					1250:1256	Different amounts	1240:1256	Different amounts of apple powder	1240:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	24	theme	Different	1240:1248	arg1	powder					1267:1272	apple powder	1261:1272	apple powder	1261:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	11	25	from	entrapment	1695:1704	arg1	surface					1729:1735	its surface	1725:1735	its surface	1725:1735	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	9	26	from	terms	1415:1419	arg1	favorable					1402:1410	favorable	1402:1410	favorable	1402:1410	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	26	from	terms	1415:1419	arg1	variant					1357:1363	the variant	1353:1363	the variant with 40% of this powder	1353:1387	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	11	27	with	material	1763:1770	arg1	characteristics					1788:1802	functional characteristics	1777:1802	functional characteristics	1777:1802	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	5	28	theme	work	638:641	arg1	results					627:633	the results	623:633	the results of work aimed at obtaining a material based entirely on natural, biodegradable raw materials	623:726	The article presents the results of work aimed at obtaining a material based entirely on natural, biodegradable raw materials.					
36674522	11	29	theme	novel	1757:1761	arg1	result					1747:1752	a result	1745:1752	a result	1745:1752	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	11	29	theme	novel	1757:1761	arg1	material					1763:1770	a novel material	1755:1770	a novel material with functional characteristics	1755:1802	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	0	30	theme	SCOBY	0:4	arg1	Cellulose					6:14	SCOBY Cellulose	0:14	SCOBY Cellulose	0:14	SCOBY Cellulose Modified with Apple Powder-Biomaterial with Functional Characteristics.					
36674522	9	31	used	used	1279:1282	arg2	amounts					1250:1256	Different amounts	1240:1256	Different amounts of apple powder	1240:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	31	used	used	1279:1282	arg2	powder					1267:1272	apple powder	1261:1272	apple powder	1261:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	6	32	theme	fermentation	780:791	arg1	byproduct					763:771	a byproduct	761:771	a byproduct of the fermentation carried out by SCOBY	761:812	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	1	33	theme	new	101:103	arg1	materials					140:148	new non-animal and non-petroleum-based materials	101:148	new non-animal and non-petroleum-based materials	101:148	The need for new non-animal and non-petroleum-based materials is strongly emphasized in the sustainable and green economy.					
36674522	3	34	theme	Vegan	359:363	arg1	"					372:372	Vegan leather"	359:372	Vegan leather"	359:372	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	9	35	theme	cellulose	1297:1305	arg1	surface					1307:1313	the cellulose surface	1293:1313	the cellulose surface	1293:1313	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	7	36	theme	cellulose	1016:1024	arg1	properties					979:988	the mechanical properties	964:988	the mechanical properties of the obtained bacterial cellulose	964:1024	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	6	37	theme	Bacterial	729:737	arg1	cellulose					739:747	Bacterial cellulose	729:747	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY	729:812	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	1	38	theme	non-animal	105:114	arg1	materials					140:148	new non-animal and non-petroleum-based materials	101:148	new non-animal and non-petroleum-based materials	101:148	The need for new non-animal and non-petroleum-based materials is strongly emphasized in the sustainable and green economy.					
36674522	3	39	theme	leather	365:371	arg1	"					372:372	Vegan leather"	359:372	Vegan leather"	359:372	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	11	40	theme	cellulose	1654:1662	arg1	properties					1621:1630	The mechanical properties	1606:1630	The mechanical properties of modified bacterial cellulose	1606:1662	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	4	41	theme	polyvinyl	582:590	arg1	chloride					592:599	polyvinyl chloride	582:599	polyvinyl chloride	582:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	8	42	theme	apple	1183:1187	arg1	layer					1196:1200	the apple powder layer	1179:1200	the apple powder layer	1179:1200	Microscopic observation of the apple powder layer showed that the coverage was uniform.					
36674522	7	43	theme	obtained	997:1004	arg1	cellulose					1016:1024	the obtained bacterial cellulose	993:1024	the obtained bacterial cellulose	993:1024	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	7	44	theme	strength	1142:1149	arg1	terms					1133:1137	terms	1133:1137	terms of strength	1133:1149	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	3	45	theme	recent	426:431	arg1	years					433:437	recent years	426:437	recent years	426:437	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	0	46	theme	Apple	30:34	arg1	Powder-Biomaterial					36:53	Apple Powder-Biomaterial	30:53	Apple Powder-Biomaterial with Functional Characteristics	30:85	SCOBY Cellulose Modified with Apple Powder-Biomaterial with Functional Characteristics.					
36674522	11	47	theme	apple	1709:1713	arg1	powder					1715:1720	apple powder	1709:1720	apple powder	1709:1720	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	3	48	theme	clothing	395:402	arg1	market					404:409	the clothing market's	391:411	the clothing market's attention	391:421	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	11	49	theme	powder	1715:1720	arg1	entrapment					1695:1704	the entrapment	1691:1704	the entrapment of apple powder on its surface	1691:1735	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	0	50	theme	Functional	60:69	arg1	Characteristics					71:85	Functional Characteristics	60:85	Functional Characteristics	60:85	SCOBY Cellulose Modified with Apple Powder-Biomaterial with Functional Characteristics.					
36674522	4	51	theme	materials	489:497	arg1	they					453:456	they	453:456	they	453:456	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	4	51	theme	materials	489:497	arg1	composites					469:478	composites	469:478	composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride	469:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	4	51	theme	materials	489:497	arg1	materials					489:497	waste materials	483:497	waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride	483:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	5	52	dep	natural	691:697	arg1	biodegradable					700:712	biodegradable	700:712	biodegradable	700:712	The article presents the results of work aimed at obtaining a material based entirely on natural, biodegradable raw materials.					
36674522	2	53	theme	valuable	241:248	arg1	resource					250:257	a valuable resource	239:257	a valuable resource	239:257	Waste materials have proven a valuable resource in this regard.					
36674522	9	54	with	variant	1357:1363	arg1	%					1372:1372	40%	1370:1372	40% of this powder	1370:1387	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	9	54	with	variant	1357:1363	arg1	powder					1382:1387	this powder	1377:1387	this powder	1377:1387	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	1	55	theme	non-petroleum-based	120:138	arg1	materials					140:148	new non-animal and non-petroleum-based materials	101:148	new non-animal and non-petroleum-based materials	101:148	The need for new non-animal and non-petroleum-based materials is strongly emphasized in the sustainable and green economy.					
36674522	7	56	theme	bacterial	1006:1014	arg1	cellulose					1016:1024	the obtained bacterial cellulose	993:1024	the obtained bacterial cellulose	993:1024	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	6	57	theme	powder	885:890	arg1	entrapment					865:874	the entrapment	861:874	the entrapment of apple powder	861:890	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	3	58	theme	large	308:312	arg1	number					314:319	quite a large number	300:319	quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years	300:437	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	3	59	from	number	314:319	arg1	fact					278:281	fact	278:281	fact	278:281	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	7	60	theme	culture	947:953	arg1	media					955:959	the SCOBY culture media	937:959	the SCOBY culture media	937:959	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	6	61	mod	modified	818:825	arg3	glycerol					832:839	glycerol	832:839	glycerol	832:839	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	6	61	mod	modified	818:825	arg1	cellulose					739:747	Bacterial cellulose	729:747	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY	729:812	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	6	62	theme	apple	879:883	arg1	powder					885:890	apple powder	879:890	apple powder	879:890	Bacterial cellulose produced as a byproduct of the fermentation carried out by SCOBY was modified with glycerol and then altered by the entrapment of apple powder.					
36674522	7	63	theme	mechanical	968:977	arg1	properties					979:988	the mechanical properties	964:988	the mechanical properties of the obtained bacterial cellulose	964:1024	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	11	64	theme	mechanical	1610:1619	arg1	properties					1621:1630	The mechanical properties	1606:1630	The mechanical properties of modified bacterial cellulose	1606:1662	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	10	65	from	use	1537:1539	arg1	durable					1526:1532	durable	1526:1532	durable	1526:1532	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
36674522	11	66	theme	modified	1635:1642	arg1	cellulose					1654:1662	modified bacterial cellulose	1635:1662	modified bacterial cellulose	1635:1662	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	4	67	with	apples	540:545	arg1	polymers					552:559	polymers	552:559	polymers like polyurethane or polyvinyl chloride	552:599	In practice, they are mostly composites of waste materials like cactus, pineapples, or, eventually, apples with polymers like polyurethane or polyvinyl chloride.					
36674522	8	68	theme	layer	1196:1200	arg1	observation					1164:1174	Microscopic observation	1152:1174	Microscopic observation of the apple powder layer	1152:1200	Microscopic observation of the apple powder layer showed that the coverage was uniform.					
36674522	11	69	theme	bacterial	1644:1652	arg1	cellulose					1654:1662	modified bacterial cellulose	1635:1662	modified bacterial cellulose	1635:1662	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	3	70	theme	goods	324:328	arg1	number					314:319	quite a large number	300:319	quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years	300:437	In fact, there have been quite a large number of goods obtained from wastes called "Vegan leather" that have gained the clothing market's attention in recent years.					
36674522	2	71	theme	Waste	211:215	arg1	materials					217:225	Waste materials	211:225	Waste materials	211:225	Waste materials have proven a valuable resource in this regard.					
36674522	7	72	theme	SCOBY	941:945	arg1	media					955:959	the SCOBY culture media	937:959	the SCOBY culture media	937:959	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	7	73	from	effect	897:902	arg1	properties					979:988	the mechanical properties	964:988	the mechanical properties of the obtained bacterial cellulose	964:1024	The effect of introducing apple powder into the SCOBY culture media on the mechanical properties of the obtained bacterial cellulose was also evaluated The resulting material acquired new mechanical characteristics that are advantageous in terms of strength.					
36674522	11	74	theme	functional	1777:1786	arg1	characteristics					1788:1802	functional characteristics	1777:1802	functional characteristics	1777:1802	The mechanical properties of modified bacterial cellulose were favorably affected by the entrapment of apple powder on its surface, and as a result, a novel material with functional characteristics was obtained.					
36674522	5	75	theme	raw	714:716	arg1	materials					718:726	natural, biodegradable raw materials	691:726	natural, biodegradable raw materials	691:726	The article presents the results of work aimed at obtaining a material based entirely on natural, biodegradable raw materials.					
36674522	9	76	theme	apple	1261:1265	arg1	powder					1267:1272	apple powder	1261:1272	apple powder	1261:1272	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	0	77	with	Powder-Biomaterial	36:53	arg1	Characteristics					71:85	Functional Characteristics	60:85	Functional Characteristics	60:85	SCOBY Cellulose Modified with Apple Powder-Biomaterial with Functional Characteristics.					
36674522	9	78	theme	mechanical	1424:1433	arg1	strength					1435:1442	mechanical strength	1424:1442	mechanical strength	1424:1442	Different amounts of apple powder were used to cover the cellulose surface from 10 to 60%, and it was found that the variant with 40% of this powder was the most favorable in terms of mechanical strength.					
36674522	10	79	theme	created	1474:1480	arg1	material					1482:1489	the created material	1470:1489	the created material	1470:1489	Also, the application of the created material as a card folder showed that it is durable in use and retains its functional characteristics for at least 1 month.					
37375244	0	0	theme	Acid	91:94	arg1	Pretreatment					96:107	Atmospheric Acetic Acid Pretreatment	72:107	Atmospheric Acetic Acid Pretreatment	72:107	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	2	1	theme	several	512:518	arg1	variables					529:537	several response variables	512:537	several response variables	512:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	2	from	effects	401:407	arg1	variables					529:537	several response variables	512:537	several response variables	512:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	4	3	theme	PDR	777:779	arg1	model					781:785	the PDR model	773:785	the PDR model	773:785	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	0	4	theme	Acetic	84:89	arg1	Pretreatment					96:107	Atmospheric Acetic Acid Pretreatment	72:107	Atmospheric Acetic Acid Pretreatment	72:107	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	4	5	from	results	758:764	arg1	deviation					726:734	a great deviation	718:734	a great deviation from the experimental results	718:764	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	4	6	theme	experimental	745:756	arg1	results					758:764	the experimental results	741:764	the experimental results	741:764	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	1	7	theme	sulfuric	234:241	arg1	SA					249:250	SA	249:250	SA	249:250	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	1	7	theme	sulfuric	234:241	arg1	acid					243:246	sulfuric acid	234:246	sulfuric acid (SA)	234:251	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	6	8	theme	residual	1181:1188	arg1	linin					1190:1194	the residual linin and acetyl group	1177:1211	linin	1190:1194	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	9	theme	solid	1090:1094	arg1	well					1096:1099	the pretreated cellulosic solid well	1064:1099	the pretreated cellulosic solid well	1064:1099	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	1	10	theme	acid	243:246	arg1	addition					222:229	the addition	218:229	the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C)	218:296	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	3	11	theme	Potential	636:644	arg1	Degree					646:651	the Potential Degree	632:651	the Potential Degree of Reaction (PDR)	632:669	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	2	12	theme	effects	500:506	arg1	effects					401:407	the effects	397:407	the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables	397:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	6	13	theme	cellulosic	1079:1088	arg1	well					1096:1099	the pretreated cellulosic solid well	1064:1099	the pretreated cellulosic solid well	1064:1099	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	2	14	theme	time	443:446	arg1	effects					401:407	the effects	397:407	the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables	397:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	5	15	theme	low	986:988	arg1	degree					990:995	the relatively low degree	971:995	the relatively low degree of delignification and acetylation of cellulose	971:1043	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	1	16	with	Pretreatment	144:155	arg1	addition					222:229	the addition	218:229	the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C)	218:296	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	6	17	theme	pretreated	1068:1077	arg1	well					1096:1099	the pretreated cellulosic solid well	1064:1099	the pretreated cellulosic solid well	1064:1099	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	1	18	theme	aqueous	187:193	arg1	AA					208:209	AA	208:209	AA	208:209	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	1	18	theme	aqueous	187:193	arg1	acid					202:205	aqueous acetic acid	187:205	aqueous acetic acid (AA)	187:210	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	0	19	theme	Peracetic	113:121	arg1	Acid					123:126	Peracetic Acid	113:126	Peracetic Acid	113:126	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	4	20	theme	great	720:724	arg1	deviation					726:734	a great deviation	718:734	a great deviation from the experimental results	718:764	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	0	21	dep	Pretreatment	96:107	arg1	Post-Treatment					128:141	Post-Treatment	128:141	Post-Treatment	128:141	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	2	22	theme	surface	328:334	arg1	methodology					336:346	A response surface methodology	317:346	A response surface methodology (central composite design)	317:373	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	22	theme	surface	328:334	arg1	design					367:372	central composite design	349:372	central composite design	349:372	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	23	theme	temperature	412:422	arg1	effects					401:407	the effects	397:407	the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables	397:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	24	theme	concentration	428:440	arg1	effects					401:407	the effects	397:407	the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables	397:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	7	25	theme	PAA	1311:1313	arg1	post-treatment					1315:1328	PAA post-treatment	1311:1328	PAA post-treatment	1311:1328	The enzymatic polysaccharide conversion increased from <30% for AA-pretreatment to about 70% for PAA post-treatment.					
37375244	2	26	theme	response	319:326	arg1	methodology					336:346	A response surface methodology	317:346	A response surface methodology (central composite design)	317:373	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	26	theme	response	319:326	arg1	design					367:372	central composite design	349:372	central composite design	349:372	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	5	27	theme	acetylation	1020:1030	arg1	degree					990:995	the relatively low degree	971:995	the relatively low degree of delignification and acetylation of cellulose	971:1043	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	2	28	theme	response	520:527	arg1	variables					529:537	several response variables	512:537	several response variables	512:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	1	29	theme	acetic	195:200	arg1	AA					208:209	AA	208:209	AA	208:209	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	1	29	theme	acetic	195:200	arg1	acid					202:205	aqueous acetic acid	187:205	aqueous acetic acid (AA)	187:210	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	0	30	theme	Enzymatic	24:32	arg1	Digestibility					34:46	the Cellulose Enzymatic Digestibility	10:46	the Cellulose Enzymatic Digestibility of Sugarcane Bagasse	10:67	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	4	31	theme	experimental	798:809	arg1	data					811:814	the experimental data	794:814	the experimental data	794:814	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	0	32	theme	Cellulose	14:22	arg1	Digestibility					34:46	the Cellulose Enzymatic Digestibility	10:46	the Cellulose Enzymatic Digestibility of Sugarcane Bagasse	10:67	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	7	33	theme	enzymatic	1218:1226	arg1	conversion					1243:1252	The enzymatic polysaccharide conversion	1214:1252	The enzymatic polysaccharide conversion	1214:1252	The enzymatic polysaccharide conversion increased from <30% for AA-pretreatment to about 70% for PAA post-treatment.					
37375244	2	34	theme	composite	357:365	arg1	methodology					336:346	A response surface methodology	317:346	A response surface methodology (central composite design)	317:373	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	34	theme	composite	357:365	arg1	design					367:372	central composite design	349:372	central composite design	349:372	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	3	35	theme	Reaction	656:663	arg1	model					622:626	Saeman's model	613:626	Saeman's model	613:626	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	3	35	theme	Reaction	656:663	arg1	Degree					646:651	the Potential Degree	632:651	the Potential Degree of Reaction (PDR)	632:669	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	2	36	theme	concentration	456:468	arg1	effects					401:407	the effects	397:407	the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables	397:537	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	7	37	theme	polysaccharide	1228:1241	arg1	conversion					1243:1252	The enzymatic polysaccharide conversion	1214:1252	The enzymatic polysaccharide conversion	1214:1252	The enzymatic polysaccharide conversion increased from <30% for AA-pretreatment to about 70% for PAA post-treatment.					
37375244	2	38	theme	central	349:355	arg1	methodology					336:346	A response surface methodology	317:346	A response surface methodology (central composite design)	317:373	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	2	38	theme	central	349:355	arg1	design					367:372	central composite design	349:372	central composite design	349:372	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	4	39	theme	0.95-0.99	862:870	arg1	coefficients					846:857	determination coefficients	832:857	determination coefficients of 0.95-0.99	832:870	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	2	40	theme	SA	453:454	arg1	concentration					456:468	SA concentration	453:468	SA concentration	453:468	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	0	41	theme	Bagasse	61:67	arg1	Digestibility					34:46	the Cellulose Enzymatic Digestibility	10:46	the Cellulose Enzymatic Digestibility of Sugarcane Bagasse	10:67	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	5	42	theme	cellulose	1035:1043	arg1	acetylation					1020:1030	acetylation	1020:1030	acetylation	1020:1030	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	5	42	theme	cellulose	1035:1043	arg1	delignification					1000:1014	delignification	1000:1014	delignification	1000:1014	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	2	43	theme	interactive	488:498	arg1	effects					500:506	their interactive effects	482:506	their interactive effects	482:506	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	6	44	theme	group	1207:1211	arg1	%					1172:1172	50-60%	1167:1172	50-60% of the residual linin and acetyl group	1167:1211	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	44	theme	group	1207:1211	arg1	linin					1190:1194	the residual linin and acetyl group	1177:1211	linin	1190:1194	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	44	theme	group	1207:1211	arg1	group					1207:1211	the residual linin and acetyl group	1177:1211	group	1207:1211	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	0	45	theme	Sugarcane	51:59	arg1	Bagasse					61:67	Sugarcane Bagasse	51:67	Sugarcane Bagasse	51:67	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	1	46	theme	mild	273:276	arg1	°C					294:295	<110 °C	289:295	<110 °C	289:295	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	1	46	theme	mild	273:276	arg1	condition					278:286	mild condition	273:286	mild condition (<110 °C)	273:296	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	5	47	theme	substrates	932:941	arg1	digestibility					897:909	poor enzymatic digestibility	882:909	poor enzymatic digestibility of the AA-pretreated substrates	882:941	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	5	48	theme	AA-pretreated	918:930	arg1	substrates					932:941	the AA-pretreated substrates	914:941	the AA-pretreated substrates	914:941	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	4	49	theme	determination	832:844	arg1	coefficients					846:857	determination coefficients	832:857	determination coefficients of 0.95-0.99	832:870	It was found that Saeman's model showed a great deviation from the experimental results, while the PDR model fitted the experimental data very well, with determination coefficients of 0.95-0.99.					
37375244	6	50	theme	well	1096:1099	arg1	Post-treatment					1046:1059	Post-treatment	1046:1059	Post-treatment of the pretreated cellulosic solid well	1046:1099	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	51	theme	linin	1190:1194	arg1	%					1172:1172	50-60%	1167:1172	50-60% of the residual linin and acetyl group	1167:1211	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	51	theme	linin	1190:1194	arg1	linin					1190:1194	the residual linin and acetyl group	1177:1211	linin	1190:1194	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	6	51	theme	linin	1190:1194	arg1	group					1207:1211	the residual linin and acetyl group	1177:1211	group	1207:1211	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	3	52	dep	model	622:626	arg1	model					671:675	model	671:675	model	671:675	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	6	53	theme	acetyl	1200:1205	arg1	group					1207:1211	the residual linin and acetyl group	1177:1211	group	1207:1211	Post-treatment of the pretreated cellulosic solid well improved the cellulose digestibly by further selectively removing 50-60% of the residual linin and acetyl group.					
37375244	3	54	theme	Kinetic	540:546	arg1	modeling					548:555	Kinetic modeling	540:555	Kinetic modeling	540:555	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	0	55	theme	Atmospheric	72:82	arg1	Pretreatment					96:107	Atmospheric Acetic Acid Pretreatment	72:107	Atmospheric Acetic Acid Pretreatment	72:107	Improving the Cellulose Enzymatic Digestibility of Sugarcane Bagasse by Atmospheric Acetic Acid Pretreatment and Peracetic Acid Post-Treatment.					
37375244	3	56	theme	AA	586:587	arg1	pretreatment					589:600	AA pretreatment	586:600	AA pretreatment	586:600	Kinetic modeling was further investigated for AA pretreatment using both Saeman's model and the Potential Degree of Reaction (PDR) model.					
37375244	5	57	theme	poor	882:885	arg1	digestibility					897:909	poor enzymatic digestibility	882:909	poor enzymatic digestibility of the AA-pretreated substrates	882:941	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	1	58	theme	sugarcane	160:168	arg1	bagasse					170:176	sugarcane bagasse	160:176	sugarcane bagasse (SCB)	160:182	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	1	58	theme	sugarcane	160:168	arg1	SCB					179:181	SCB	179:181	SCB	179:181	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
37375244	2	59	theme	AA	425:426	arg1	concentration					428:440	AA concentration	425:440	AA concentration	425:440	A response surface methodology (central composite design) was employed to study the effects of temperature, AA concentration, time, and SA concentration, as well as their interactive effects, on several response variables.					
37375244	5	60	theme	delignification	1000:1014	arg1	degree					990:995	the relatively low degree	971:995	the relatively low degree of delignification and acetylation of cellulose	971:1043	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	5	61	theme	enzymatic	887:895	arg1	digestibility					897:909	poor enzymatic digestibility	882:909	poor enzymatic digestibility of the AA-pretreated substrates	882:941	However, poor enzymatic digestibility of the AA-pretreated substrates was observed, mainly due to the relatively low degree of delignification and acetylation of cellulose.					
37375244	1	62	theme	bagasse	170:176	arg1	Pretreatment					144:155	Pretreatment	144:155	Pretreatment	144:155	Pretreatment of sugarcane bagasse (SCB) by aqueous acetic acid (AA), with the addition of sulfuric acid (SA) as a catalyst under mild condition (<110 °C), was investigated.					
35773380	8	0	theme	sulfate	1348:1354	arg1	concentration					1356:1368	sulfate concentration	1348:1368	sulfate concentration	1348:1368	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	8	1	theme	G.	1299:1300	arg1	culture					1311:1317	G. gracilis culture	1299:1317	G. gracilis culture	1299:1317	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	3	2	theme	biochemical	477:487	arg1	composition					489:499	their biochemical composition	471:499	their growth as well as their biochemical composition	447:499	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	3	theme	sulfur	600:605	arg1	seawater					616:623	sulfur enriched seawater	600:623	sulfur enriched seawater	600:623	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	3	theme	sulfur	600:605	arg1	SES					595:597	SES	595:597	SES (sulfur enriched seawater)	595:624	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	1	4	theme	coastal	162:168	arg1	regions					170:176	coastal regions	162:176	coastal regions	162:176	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	5	5	theme	alga	831:834	arg1	growth					836:841	alga growth	831:841	alga growth	831:841	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	0	6	from	Effects	0:6	arg1	growth					76:81	Gracilaria gracilis growth	56:81	Gracilaria gracilis growth	56:81	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	0	6	from	Effects	0:6	arg1	composition					99:109	biochemical composition	87:109	biochemical composition	87:109	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	2	7	theme	interest	276:283	arg1	spate					267:271	a spate	265:271	a spate of interest	265:283	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	2	8	from	culture	292:298	arg1	lagoon					303:308	lagoon	303:308	lagoon	303:308	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	0	9	theme	biochemical	87:97	arg1	composition					99:109	biochemical composition	87:109	biochemical composition	87:109	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	7	10	theme	severe	1107:1112	arg1	retardation					1121:1131	severe growth retardation	1107:1131	severe growth retardation	1107:1131	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	10	theme	severe	1107:1112	arg1	quality					1155:1161	quality	1155:1161	quality	1155:1161	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	10	theme	severe	1107:1112	arg1	yield					1145:1149	lower agar yield	1134:1149	lower agar yield	1134:1149	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	11	theme	lower	1134:1138	arg1	retardation					1121:1131	severe growth retardation	1107:1131	severe growth retardation	1107:1131	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	11	theme	lower	1134:1138	arg1	yield					1145:1149	lower agar yield	1134:1149	lower agar yield	1134:1149	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	2	12	theme	water	320:324	arg1	concentration					334:346	the water sulfate concentration	316:346	the water sulfate concentration	316:346	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	2	12	theme	water	320:324	arg1	variable					351:358	variable	351:358	variable	351:358	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	1	13	from	producer	150:157	arg1	regions					170:176	coastal regions	162:176	coastal regions	162:176	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	7	14	theme	G.	1200:1201	arg1	gracilis					1203:1210	G. gracilis	1200:1210	G. gracilis	1200:1210	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	3	15	theme	sulfate	415:421	arg1	effect					437:442	the sulfate concentration effect	411:442	the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater)	411:624	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	5	16	dep	environment	808:818	arg1	affects					924:930	affects	924:930	affects them	924:935	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	5	16	dep	environment	808:818	arg1	sustain					823:829	sustain	823:829	to sustain alga growth, proteins, R-phycoerythrin and agar yields	820:884	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	4	17	theme	medium	679:684	arg1	content					652:658	the sulfate content	640:658	the sulfate content of the surrounding medium	640:684	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	4	17	theme	medium	679:684	arg1	parameter					695:703	a key parameter	689:703	a key parameter influencing both the alga growth and its composition	689:756	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	2	18	dep	Nowadays	246:253	arg1	there					256:260	there	256:260	there	256:260	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	3	19	theme	laboratory	363:372	arg1	culture					374:380	A laboratory culture	361:380	A laboratory culture	361:380	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	4	20	theme	sulfate	644:650	arg1	content					652:658	the sulfate content	640:658	the sulfate content of the surrounding medium	640:684	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	4	20	theme	sulfate	644:650	arg1	parameter					695:703	a key parameter	689:703	a key parameter influencing both the alga growth and its composition	689:756	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	7	21	theme	sulfur	1056:1061	arg1	2.5 mM					1075:1080	2.5 mM	1075:1080	2.5 mM	1075:1080	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	21	theme	sulfur	1056:1061	arg1	starvation					1063:1072	sulfur starvation	1056:1072	sulfur starvation (2.5 mM)	1056:1081	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	3	22	theme	enriched	607:614	arg1	seawater					616:623	sulfur enriched seawater	600:623	sulfur enriched seawater	600:623	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	22	theme	enriched	607:614	arg1	SES					595:597	SES	595:597	SES (sulfur enriched seawater)	595:624	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	7	23	theme	limit	1181:1185	arg1	potential					1187:1195	the limit potential	1177:1195	the limit potential of G. gracilis for mariculture	1177:1226	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	0	24	theme	sulfur	20:25	arg1	starvation					27:36	seawater sulfur starvation	11:36	seawater sulfur starvation	11:36	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	6	25	theme	agar	960:963	arg1	related					994:1000	related	994:1000	related	994:1000	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	6	25	theme	agar	960:963	arg1	degree					950:955	The sulfate degree	938:955	The sulfate degree of agar and therefore its quality	938:989	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	7	26	theme	gracilis	1203:1210	arg1	potential					1187:1195	the limit potential	1177:1195	the limit potential of G. gracilis for mariculture	1177:1226	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	1	27	theme	wide	193:196	arg1	gracilis					236:243	Gracilaria gracilis	225:243	Gracilaria gracilis	225:243	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	27	theme	wide	193:196	arg1	range					198:202	a wide range	191:202	a wide range of species including Gracilaria gracilis	191:243	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	0	28	theme	seawater	11:18	arg1	starvation					27:36	seawater sulfur starvation	11:36	seawater sulfur starvation	11:36	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	8	29	theme	culture	1311:1317	arg1	success					1288:1294	the success	1284:1294	the success of G. gracilis culture in the lagoon	1284:1331	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	8	29	theme	culture	1311:1317	arg1	feasible					1336:1343	feasible	1336:1343	feasible	1336:1343	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	2	30	theme	sulfate	326:332	arg1	concentration					334:346	the water sulfate concentration	316:346	the water sulfate concentration	316:346	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	2	30	theme	sulfate	326:332	arg1	variable					351:358	variable	351:358	variable	351:358	Nowadays, there is a spate of interest in its culture in lagoon where the water sulfate concentration is variable.					
35773380	8	31	from	success	1288:1294	arg1	lagoon					1326:1331	the lagoon	1322:1331	the lagoon	1322:1331	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	7	32	theme	growth	1114:1119	arg1	retardation					1121:1131	severe growth retardation	1107:1131	severe growth retardation	1107:1131	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	32	theme	growth	1114:1119	arg1	quality					1155:1161	quality	1155:1161	quality	1155:1161	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	32	theme	growth	1114:1119	arg1	yield					1145:1149	lower agar yield	1134:1149	lower agar yield	1134:1149	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	8	33	theme	gracilis	1302:1309	arg1	culture					1311:1317	G. gracilis culture	1299:1317	G. gracilis culture	1299:1317	These results demonstrated that the success of G. gracilis culture in the lagoon is feasible if sulfate concentration is closer to that of seawater.					
35773380	0	34	theme	starvation	27:36	arg1	Effects					0:6	Effects	0:6	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.	0:110	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	3	35	from	effect	437:442	arg1	composition					489:499	their biochemical composition	471:499	their growth as well as their biochemical composition	447:499	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	35	from	effect	437:442	arg1	growth					453:458	their growth	447:458	their growth as well as their biochemical composition	447:499	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	1	36	theme	species	207:213	arg1	gracilis					236:243	Gracilaria gracilis	225:243	Gracilaria gracilis	225:243	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	36	theme	species	207:213	arg1	range					198:202	a wide range	191:202	a wide range of species including Gracilaria gracilis	191:243	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	37	theme	genus	116:120	arg1	producer					150:157	largest biomass producer	134:157	largest biomass producer in coastal regions	134:176	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	37	theme	genus	116:120	arg1	Gracilaria					122:131	The genus Gracilaria	112:131	The genus Gracilaria	112:131	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	0	38	theme	enrichment	42:51	arg1	Effects					0:6	Effects	0:6	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.	0:110	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	4	39	theme	alga	726:729	arg1	growth					731:736	the alga growth	722:736	the alga growth	722:736	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	7	40	theme	agar	1140:1143	arg1	retardation					1121:1131	severe growth retardation	1107:1131	severe growth retardation	1107:1131	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	7	40	theme	agar	1140:1143	arg1	yield					1145:1149	lower agar yield	1134:1149	lower agar yield	1134:1149	We conclude that sulfur starvation (2.5 mM) for three weeks, led to severe growth retardation, lower agar yield and quality and indicated the limit potential of G. gracilis for mariculture under these conditions.					
35773380	5	41	theme	sulfur	891:896	arg1	enrichment					898:907	sulfur enrichment	891:907	sulfur enrichment	891:907	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	4	42	theme	key	691:693	arg1	parameter					695:703	a key parameter	689:703	a key parameter influencing both the alga growth and its composition	689:756	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	4	42	theme	key	691:693	arg1	content					652:658	the sulfate content	640:658	the sulfate content of the surrounding medium	640:684	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	5	43	theme	agar	874:877	arg1	yields					879:884	agar yields	874:884	agar yields	874:884	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	5	44	theme	suitable	799:806	arg1	environment					808:818	the most suitable environment	790:818	the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them	790:935	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	5	44	theme	suitable	799:806	arg1	seawater					768:775	seawater	768:775	seawater	768:775	However, seawater proved to be the most suitable environment to sustain alga growth, proteins, R-phycoerythrin and agar yields, but sulfur enrichment and starvation affects them.					
35773380	4	45	theme	surrounding	667:677	arg1	medium					679:684	the surrounding medium	663:684	the surrounding medium	663:684	We found that the sulfate content of the surrounding medium is a key parameter influencing both the alga growth and its composition.					
35773380	1	46	theme	largest	134:140	arg1	producer					150:157	largest biomass producer	134:157	largest biomass producer in coastal regions	134:176	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	46	theme	largest	134:140	arg1	Gracilaria					122:131	The genus Gracilaria	112:131	The genus Gracilaria	112:131	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	6	47	theme	medium	1009:1014	arg1	concentration					1024:1036	the medium sulfate concentration	1005:1036	the medium sulfate concentration	1005:1036	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	1	48	theme	Gracilaria	225:234	arg1	gracilis					236:243	Gracilaria gracilis	225:243	Gracilaria gracilis	225:243	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	0	49	theme	gracilis	67:74	arg1	growth					76:81	Gracilaria gracilis growth	56:81	Gracilaria gracilis growth	56:81	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	3	50	theme	sulfur	551:556	arg1	SSS					546:548	SSS	546:548	SSS (sulfur starved seawater)	546:574	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	50	theme	sulfur	551:556	arg1	seawater					566:573	sulfur starved seawater	551:573	sulfur starved seawater	551:573	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	6	51	theme	sulfate	942:948	arg1	related					994:1000	related	994:1000	related	994:1000	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	6	51	theme	sulfate	942:948	arg1	degree					950:955	The sulfate degree	938:955	The sulfate degree of agar and therefore its quality	938:989	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	1	52	theme	biomass	142:148	arg1	producer					150:157	largest biomass producer	134:157	largest biomass producer in coastal regions	134:176	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	1	52	theme	biomass	142:148	arg1	Gracilaria					122:131	The genus Gracilaria	112:131	The genus Gracilaria	112:131	The genus Gracilaria, largest biomass producer in coastal regions, encompasses a wide range of species including Gracilaria gracilis.					
35773380	3	53	theme	concentration	423:435	arg1	effect					437:442	the sulfate concentration effect	411:442	the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater)	411:624	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	0	54	theme	Gracilaria	56:65	arg1	growth					76:81	Gracilaria gracilis growth	56:81	Gracilaria gracilis growth	56:81	Effects of seawater sulfur starvation and enrichment on Gracilaria gracilis growth and biochemical composition.					
35773380	6	55	theme	sulfate	1016:1022	arg1	concentration					1024:1036	the medium sulfate concentration	1005:1036	the medium sulfate concentration	1005:1036	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	3	56	theme	starved	558:564	arg1	SSS					546:548	SSS	546:548	SSS (sulfur starved seawater)	546:574	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	3	56	theme	starved	558:564	arg1	seawater					566:573	sulfur starved seawater	551:573	sulfur starved seawater	551:573	A laboratory culture was carried out to determine the sulfate concentration effect on their growth as well as their biochemical composition, which were 2.5, 27 or 50 mM, referred to as SSS (sulfur starved seawater), SW (seawater) and SES (sulfur enriched seawater).					
35773380	6	57	theme	quality	983:989	arg1	related					994:1000	related	994:1000	related	994:1000	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
35773380	6	57	theme	quality	983:989	arg1	degree					950:955	The sulfate degree	938:955	The sulfate degree of agar and therefore its quality	938:989	The sulfate degree of agar and therefore its quality is related to the medium sulfate concentration.					
37402426	2	0	theme	environmental	572:584	arg1	issues					599:604	environmental and economic issues	572:604	environmental and economic issues	572:604	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	8	1	theme	film	1921:1924	arg1	matrix					1926:1931	the composite film matrix	1907:1931	the composite film matrix	1907:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	15	2	theme	MF	2987:2988	arg1	range					2978:2982	the range	2974:2982	the range of MF	2974:2988	The size of this composite film may be therefore considered in the range of MF.					
37402426	3	3	theme	nanocomposite	681:693	arg1	films					695:699	PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films	630:699	PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films	630:699	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	13	4	theme	BSA	2744:2746	arg1	200 mg/L					2732:2739	200 mg/L	2732:2739	200 mg/L of BSA	2732:2746	Performance evaluation of the PVA/CNF0.5 composite film showed that 46.3% and 92.8% yield were found in the retentate for 200 mg/L of BSA, and 5 × 107 CFU/mL respectively.					
37402426	7	5	theme	malic	1568:1572	arg1	acid					1574:1577	malic acid	1568:1577	malic acid	1568:1577	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	5	6	theme	composite	1208:1216	arg1	films					1218:1222	PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films	1161:1222	PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films	1161:1222	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	2	7	theme	economic	590:597	arg1	issues					599:604	environmental and economic issues	572:604	environmental and economic issues	572:604	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	8	8	dep	temperature	1602:1612	arg1	max					1618:1620	max	1618:1620	max	1618:1620	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	8	dep	temperature	1602:1612	arg1	Td					1615:1616	Td	1615:1616	Td	1615:1616	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	10	9	dep	found	2146:2150	arg1	followed					2168:2175	followed	2168:2175	followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0	2168:2227	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	1	10	theme	nanofiber	196:204	arg1	production					172:181	production	172:181	production of cellulose nanofiber (CNF) from waste materials	172:231	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	4	11	theme	water	851:855	arg1	absorption					857:866	The strongest water absorption	837:866	The strongest water absorption behaviour	837:876	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	7	12	theme	unique	1420:1425	arg1	peaks					1427:1431	unique peaks	1420:1431	unique peaks	1420:1431	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	11	13	theme	maximum	2234:2240	arg1	111 MPa					2259:2265	111 MPa	2259:2265	111 MPa	2259:2265	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	11	13	theme	maximum	2234:2240	arg1	modulus					2250:2256	The maximum young's modulus	2230:2256	The maximum young's modulus (111 MPa)	2230:2266	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	11	14	theme	molecular	2408:2416	arg1	structures					2418:2427	the molecular structures	2404:2427	the molecular structures	2404:2427	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	3	15	theme	solvent	725:731	arg1	approach					741:748	the solvent casting approach	721:748	the solvent casting approach	721:748	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	6	16	theme	pores	1372:1376	arg1	number					1362:1367	number	1362:1367	number	1362:1367	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37402426	6	16	theme	pores	1372:1376	arg1	sizes					1352:1356	sizes	1352:1356	sizes	1352:1356	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37402426	6	17	dep	sizes	1352:1356	arg1	the					1348:1350	the	1348:1350	the	1348:1350	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37402426	7	18	theme	XRD	1392:1394	arg1	analysis					1396:1403	XRD analysis	1392:1403	XRD analysis	1392:1403	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	2	19	theme	sustainable	531:541	arg1	way					543:545	a sustainable way	529:545	a sustainable way of monetizing to address environmental and economic issues	529:604	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	19	theme	sustainable	531:541	arg1	material					494:501	the composite material	480:501	the composite material	480:501	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	11	20	theme	pure	2346:2349	arg1	PVA					2351:2353	pure PVA	2346:2353	pure PVA	2346:2353	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	1	21	from	materials	223:231	arg1	production					172:181	production	172:181	production of cellulose nanofiber (CNF) from waste materials	172:231	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	7	22	theme	new	1506:1508	arg1	plane					1518:1522	new crystal plane	1506:1522	new crystal plane generated upon cross-linking in presence of malic acid	1506:1577	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	2	23	theme	composite	484:492	arg1	way					543:545	a sustainable way	529:545	a sustainable way of monetizing to address environmental and economic issues	529:604	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	23	theme	composite	484:492	arg1	material					494:501	the composite material	480:501	the composite material	480:501	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	5	24	theme	water	1103:1107	arg1	droplet					1109:1115	water droplet	1103:1115	water droplet	1103:1115	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	9	25	theme	surface	1980:1986	arg1	porosity					1988:1995	a surface porosity	1978:1995	a surface porosity	1978:1995	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	8	26	theme	273.4 °C.	1705:1713	arg1	studies					1720:1726	273.4 °C. FTIR studies	1705:1726	273.4 °C. FTIR studies	1705:1726	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	1	27	theme	recent	158:163	arg1	years					165:169	recent years	158:169	recent years	158:169	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	14	28	dep	%	2803:2803	arg1	coli					2808:2811	E. coli	2805:2811	more than 90% E. coli	2791:2811	However, more than 90% E. coli was retained by PVA/CNF0.5 composite film, therefore absolute rating of this membrane is 0.22 μm.					
37402426	4	29	theme	PVA	907:909	arg1	membrane					911:918	pure PVA membrane	902:918	pure PVA membrane	902:918	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	1	30	theme	economic	340:347	arg1	value					349:353	economic value	340:353	economic value	340:353	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	8	31	theme	maximum	1584:1590	arg1	rate					1597:1600	The maximum loss rate	1580:1600	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5	1580:1660	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	3	32	theme	2.0 wt	793:798	arg1	%					799:799	2.0 wt%	793:799	2.0 wt% of CNF concentrations	793:821	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	3	32	theme	2.0 wt	793:798	arg1	concentrations					808:821	CNF concentrations	804:821	CNF concentrations	804:821	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	13	33	theme	film	2661:2664	arg1	evaluation					2622:2631	Performance evaluation	2610:2631	Performance evaluation of the PVA/CNF0.5 composite film	2610:2664	Performance evaluation of the PVA/CNF0.5 composite film showed that 46.3% and 92.8% yield were found in the retentate for 200 mg/L of BSA, and 5 × 107 CFU/mL respectively.					
37402426	5	34	theme	32.3°	1078:1082	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	9	35	theme	pore	2006:2009	arg1	size					2011:2014	mean pore size	2001:2014	mean pore size	2001:2014	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	0	36	theme	alcohol/	90:97	arg1	nanofiber					109:117	polyvinyl alcohol/ cellulose nanofiber	80:117	polyvinyl alcohol/ cellulose nanofiber	80:117	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	8	37	theme	rate	1597:1600	arg1	temperature					1602:1612	The maximum loss rate temperature	1580:1612	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5	1580:1660	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	9	38	contain	have	1973:1976	arg2	size					2011:2014	mean pore size	2001:2014	mean pore size	2001:2014	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	9	38	contain	have	1973:1976	arg2	porosity					1988:1995	a surface porosity	1978:1995	a surface porosity	1978:1995	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	9	38	contain	have	1973:1976	arg1	film					1955:1958	PVA/CNF0.5 composite film	1934:1958	PVA/CNF0.5 composite film	1934:1958	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	0	39	theme	nanofiber	109:117	arg1	films					71:75	composite films	61:75	composite films of polyvinyl alcohol/ cellulose nanofiber	61:117	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	1	40	theme	low	360:362	arg1	density					364:370	low density	360:370	low density	360:370	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	3	41	theme	concentrations	808:821	arg1	%					799:799	2.0 wt%	793:799	2.0 wt% of CNF concentrations	793:821	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	3	41	theme	concentrations	808:821	arg1	concentrations					808:821	CNF concentrations	804:821	CNF concentrations	804:821	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	0	42	theme	films	71:75	arg1	characterization					13:28	characterization	13:28	characterization	13:28	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	0	42	theme	films	71:75	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	0	42	theme	films	71:75	arg1	evaluation					47:56	performance evaluation	35:56	performance evaluation	35:56	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	5	43	theme	PVA	1156:1158	arg1	droplet					1109:1115	water droplet	1103:1115	water droplet	1103:1115	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	5	43	theme	PVA	1156:1158	arg1	interface					1138:1146	the solid-liquid interface	1121:1146	the solid-liquid interface of pure PVA	1121:1158	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	9	44	theme	%	2024:2024	arg1	porosity					1988:1995	a surface porosity	1978:1995	a surface porosity	1978:1995	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	9	44	theme	%	2024:2024	arg1	size					2011:2014	mean pore size	2001:2014	mean pore size	2001:2014	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	8	45	attach	presence	1868:1875	arg1	matrix					1926:1931	the composite film matrix	1907:1931	the composite film matrix	1907:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	45	attach	presence	1868:1875	arg2	band					1899:1902	higher crystalline band	1880:1902	higher crystalline band	1880:1902	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	46	theme	PVA/CNF	1827:1833	arg1	films					1845:1849	other PVA/CNF composite films	1821:1849	other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix	1821:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	2	47	theme	synthetic	410:418	arg1	biopolymer					420:429	a synthetic biopolymer	408:429	a synthetic biopolymer with good water solubility and biocompatibility	408:477	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	47	theme	synthetic	410:418	arg1	alcohol					391:397	Polyvinyl alcohol	381:397	Polyvinyl alcohol (PVA)	381:403	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	9	48	theme	0.19	2030:2033	arg1	μm					2035:2036	0.19 μm	2030:2036	0.19 μm	2030:2036	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	8	49	theme	highest	1780:1786	arg1	peak					1788:1791	the highest peak	1776:1791	the highest peak at 1428 cm-1	1776:1804	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	5	50	theme	water	1023:1027	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	3	51	theme	pure	620:623	arg1	PVA					625:627	this work pure PVA	610:627	this work pure PVA	610:627	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	5	52	theme	solid-liquid	1125:1136	arg1	interface					1138:1146	the solid-liquid interface	1121:1146	the solid-liquid interface of pure PVA	1121:1158	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	15	53	theme	film	2938:2941	arg1	size					2915:2918	The size	2911:2918	The size of this composite film	2911:2941	The size of this composite film may be therefore considered in the range of MF.					
37402426	2	54	theme	water	441:445	arg1	solubility					447:456	good water solubility	436:456	good water solubility	436:456	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	0	55	theme	composite	61:69	arg1	films					71:75	composite films	61:75	composite films of polyvinyl alcohol/ cellulose nanofiber	61:117	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	1	56	theme	high	312:315	arg1	properties					328:337	high mechanical properties	312:337	high mechanical properties	312:337	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	14	57	theme	membrane	2890:2897	arg1	rating					2875:2880	absolute rating	2866:2880	absolute rating of this membrane	2866:2897	However, more than 90% E. coli was retained by PVA/CNF0.5 composite film, therefore absolute rating of this membrane is 0.22 μm.					
37402426	7	58	from	cross-linking	1539:1551	arg1	presence					1556:1563	presence	1556:1563	presence of malic acid	1556:1577	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	5	59	theme	47.8°	1053:1057	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	8	60	from	presence	1868:1875	arg1	matrix					1926:1931	the composite film matrix	1907:1931	the composite film matrix	1907:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	61	theme	crystalline	1887:1897	arg1	band					1899:1902	higher crystalline band	1880:1902	higher crystalline band	1880:1902	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	9	62	theme	MF	2074:2075	arg1	category					2086:2093	the MF membrane category	2070:2093	the MF membrane category	2070:2093	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	5	63	theme	43.4°	1060:1064	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	12	64	theme	greater	2467:2473	arg1	elongation					2475:2484	greater elongation	2467:2484	greater elongation at break (21.7) than the other polymers	2467:2524	PVA/CNF0.5 exhibits greater elongation at break (21.7) than the other polymers, indicating a material's ability to undergo significant deformation before failure.					
37402426	10	65	theme	maximum	2100:2106	arg1	TS					2126:2127	TS	2126:2127	TS	2126:2127	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	10	65	theme	maximum	2100:2106	arg1	strength					2116:2123	The maximum tensile strength	2096:2123	The maximum tensile strength (TS) of 5.27 MPa	2096:2140	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	1	66	theme	great	246:250	arg1	interest					252:259	great interest	246:259	great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density	246:370	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	7	67	theme	acid	1574:1577	arg1	presence					1556:1563	presence	1556:1563	presence of malic acid	1556:1577	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	8	68	theme	composite	1911:1919	arg1	matrix					1926:1931	the composite film matrix	1907:1931	the composite film matrix	1907:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	5	69	theme	53.1°	1046:1050	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	2	70	theme	monetizing	550:559	arg1	way					543:545	a sustainable way	529:545	a sustainable way of monetizing to address environmental and economic issues	529:604	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	70	theme	monetizing	550:559	arg1	material					494:501	the composite material	480:501	the composite material	480:501	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	9	71	theme	mean	2001:2004	arg1	size					2011:2014	mean pore size	2001:2014	mean pore size	2001:2014	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	6	72	theme	composite	1326:1334	arg1	film					1336:1339	the PVA/CNF0.5 composite film	1311:1339	the PVA/CNF0.5 composite film	1311:1339	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37402426	1	73	theme	cellulose	186:194	arg1	CNF					207:209	CNF	207:209	CNF	207:209	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	1	73	theme	cellulose	186:194	arg1	nanofiber					196:204	cellulose nanofiber	186:204	cellulose nanofiber (CNF)	186:210	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	3	74	theme	1.5	784:786	arg1	addition					759:766	the addition	755:766	the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively	755:834	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	12	75	theme	other	2511:2515	arg1	polymers					2517:2524	the other polymers	2507:2524	the other polymers	2507:2524	PVA/CNF0.5 exhibits greater elongation at break (21.7) than the other polymers, indicating a material's ability to undergo significant deformation before failure.					
37402426	4	76	theme	strongest	841:849	arg1	absorption					857:866	The strongest water absorption	837:866	The strongest water absorption behaviour	837:876	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	9	77	theme	composite	1945:1953	arg1	film					1955:1958	PVA/CNF0.5 composite film	1934:1958	PVA/CNF0.5 composite film	1934:1958	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	8	78	theme	TG	1680:1681	arg1	analysis					1683:1690	TG analysis	1680:1690	TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix	1680:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	12	79	from	break	2489:2493	arg1	elongation					2475:2484	greater elongation	2467:2484	greater elongation at break (21.7) than the other polymers	2467:2524	PVA/CNF0.5 exhibits greater elongation at break (21.7) than the other polymers, indicating a material's ability to undergo significant deformation before failure.					
37402426	4	80	theme	absorption	857:866	arg1	%					896:896	25.82%	891:896	25.82% for pure PVA membrane	891:918	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	4	80	theme	absorption	857:866	arg1	behaviour					868:876	The strongest water absorption behaviour	837:876	The strongest water absorption behaviour	837:876	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	10	81	theme	pure	2204:2207	arg1	PVA					2209:2211	pure PVA	2204:2211	pure PVA	2204:2211	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	3	82	theme	casting	733:739	arg1	approach					741:748	the solvent casting approach	721:748	the solvent casting approach	721:748	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	2	83	with	biopolymer	420:429	arg1	biocompatibility					462:477	biocompatibility	462:477	biocompatibility	462:477	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	83	with	biopolymer	420:429	arg1	solubility					447:456	good water solubility	436:456	good water solubility	436:456	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	11	84	theme	young	2242:2246	arg1	111 MPa					2259:2265	111 MPa	2259:2265	111 MPa	2259:2265	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	11	84	theme	young	2242:2246	arg1	modulus					2250:2256	The maximum young's modulus	2230:2256	The maximum young's modulus (111 MPa)	2230:2266	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	3	85	theme	0	771:771	arg1	addition					759:766	the addition	755:766	the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively	755:834	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	8	86	theme	FTIR	1715:1718	arg1	studies					1720:1726	273.4 °C. FTIR studies	1705:1726	273.4 °C. FTIR studies	1705:1726	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	7	87	theme	crystal	1510:1516	arg1	plane					1518:1522	new crystal plane	1506:1522	new crystal plane generated upon cross-linking in presence of malic acid	1506:1577	XRD analysis suggested that unique peaks found at 2θ = 17.5°, 28.1°, 33.4°, and 38° for nanocomposites indicating new crystal plane generated upon cross-linking in presence of malic acid.					
37402426	10	88	theme	tensile	2108:2114	arg1	TS					2126:2127	TS	2126:2127	TS	2126:2127	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	10	88	theme	tensile	2108:2114	arg1	strength					2116:2123	The maximum tensile strength	2096:2123	The maximum tensile strength (TS) of 5.27 MPa	2096:2140	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	1	89	theme	waste	217:221	arg1	materials					223:231	waste materials	217:231	waste materials	217:231	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	5	90	theme	37.7°	1067:1071	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	0	91	theme	polyvinyl	80:88	arg1	nanofiber					109:117	polyvinyl alcohol/ cellulose nanofiber	80:117	polyvinyl alcohol/ cellulose nanofiber	80:117	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	14	92	theme	absolute	2866:2873	arg1	rating					2875:2880	absolute rating	2866:2880	absolute rating of this membrane	2866:2897	However, more than 90% E. coli was retained by PVA/CNF0.5 composite film, therefore absolute rating of this membrane is 0.22 μm.					
37402426	3	93	theme	CNF	804:806	arg1	concentrations					808:821	CNF concentrations	804:821	CNF concentrations	804:821	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	13	94	theme	composite	2651:2659	arg1	film					2661:2664	the PVA/CNF0.5 composite film	2636:2664	the PVA/CNF0.5 composite film	2636:2664	Performance evaluation of the PVA/CNF0.5 composite film showed that 46.3% and 92.8% yield were found in the retentate for 200 mg/L of BSA, and 5 × 107 CFU/mL respectively.					
37402426	4	95	theme	pure	902:905	arg1	membrane					911:918	pure PVA membrane	902:918	pure PVA membrane	902:918	The strongest water absorption behaviour was found as 25.82% for pure PVA membrane, followed by PVA/CNF0.5 (20.71%), PVA/CNF1.0 (10.26%), PVA/CNF1.5 (9.63%), and PVA/CNF2.0 (4.35%).					
37402426	3	96	theme	1.0	779:781	arg1	addition					759:766	the addition	755:766	the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively	755:834	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	0	97	theme	cellulose	99:107	arg1	nanofiber					109:117	polyvinyl alcohol/ cellulose nanofiber	80:117	polyvinyl alcohol/ cellulose nanofiber	80:117	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	3	98	theme	%	799:799	arg1	addition					759:766	the addition	755:766	the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively	755:834	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	3	99	theme	0.5	774:776	arg1	addition					759:766	the addition	755:766	the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively	755:834	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	8	100	theme	loss	1592:1595	arg1	rate					1597:1600	The maximum loss rate	1580:1600	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5	1580:1660	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	101	theme	other	1821:1825	arg1	films					1845:1849	other PVA/CNF composite films	1821:1849	other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix	1821:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	8	102	from	1428 cm-1	1796:1804	arg1	peak					1788:1791	the highest peak	1776:1791	the highest peak at 1428 cm-1	1776:1804	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	5	103	theme	pure	1151:1154	arg1	PVA					1156:1158	pure PVA	1151:1158	pure PVA	1151:1158	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	2	104	theme	Polyvinyl	381:389	arg1	biopolymer					420:429	a synthetic biopolymer	408:429	a synthetic biopolymer with good water solubility and biocompatibility	408:477	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	104	theme	Polyvinyl	381:389	arg1	PVA					400:402	PVA	400:402	PVA	400:402	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	2	104	theme	Polyvinyl	381:389	arg1	alcohol					391:397	Polyvinyl alcohol	381:397	Polyvinyl alcohol (PVA)	381:403	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	8	105	theme	composite	1835:1843	arg1	films					1845:1849	other PVA/CNF composite films	1821:1849	other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix	1821:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	13	106	theme	Performance	2610:2620	arg1	evaluation					2622:2631	Performance evaluation	2610:2631	Performance evaluation of the PVA/CNF0.5 composite film	2610:2664	Performance evaluation of the PVA/CNF0.5 composite film showed that 46.3% and 92.8% yield were found in the retentate for 200 mg/L of BSA, and 5 × 107 CFU/mL respectively.					
37402426	6	107	theme	SEM	1242:1244	arg1	image					1246:1250	The SEM image	1238:1250	The SEM image	1238:1250	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37402426	1	108	theme	renewable	276:284	arg1	nature					286:291	their renewable nature	270:291	their renewable nature	270:291	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	14	109	theme	composite	2840:2848	arg1	film					2850:2853	PVA/CNF0.5 composite film	2829:2853	PVA/CNF0.5 composite film	2829:2853	However, more than 90% E. coli was retained by PVA/CNF0.5 composite film, therefore absolute rating of this membrane is 0.22 μm.					
37402426	10	110	theme	5.27 MPa	2133:2140	arg1	TS					2126:2127	TS	2126:2127	TS	2126:2127	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	10	110	theme	5.27 MPa	2133:2140	arg1	strength					2116:2123	The maximum tensile strength	2096:2123	The maximum tensile strength (TS) of 5.27 MPa	2096:2140	The maximum tensile strength (TS) of 5.27 MPa was found for PVA/CNF0.5, followed by PVA/CNF1.0, PVA/CNF1.5, pure PVA, and PVA/CNF2.0.					
37402426	3	111	theme	work	615:618	arg1	PVA					625:627	this work pure PVA	610:627	this work pure PVA	610:627	In this work pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, and PVA/CNF2.0 nanocomposite films were produced using the solvent casting approach with the addition of 0, 0.5, 1.0, 1.5, and 2.0 wt% of CNF concentrations respectively.					
37402426	9	112	theme	μm	2035:2036	arg1	porosity					1988:1995	a surface porosity	1978:1995	a surface porosity	1978:1995	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	9	112	theme	μm	2035:2036	arg1	size					2011:2014	mean pore size	2001:2014	mean pore size	2001:2014	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	0	113	theme	performance	35:45	arg1	evaluation					47:56	performance evaluation	35:56	performance evaluation	35:56	Preparation, characterization, and performance evaluation of composite films of polyvinyl alcohol/ cellulose nanofiber extracted from Imperata cylindrica.					
37402426	5	114	theme	contact	1029:1035	arg1	angle					1037:1041	The water contact angle	1019:1041	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3°	1019:1082	The water contact angle of 53.1°, 47.8°, 43.4°, 37.7°, and 32.3° was formed between water droplet and the solid-liquid interface of pure PVA, PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5, PVA/CNF2.0 composite films respectively.					
37402426	8	115	theme	composite	1754:1762	arg1	film					1764:1767	PVA/CNF0.5 composite film	1743:1767	PVA/CNF0.5 composite film	1743:1767	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	13	116	theme	PVA/CNF0.5	2640:2649	arg1	film					2661:2664	the PVA/CNF0.5 composite film	2636:2664	the PVA/CNF0.5 composite film	2636:2664	Performance evaluation of the PVA/CNF0.5 composite film showed that 46.3% and 92.8% yield were found in the retentate for 200 mg/L of BSA, and 5 × 107 CFU/mL respectively.					
37402426	8	117	theme	higher	1880:1885	arg1	band					1899:1902	higher crystalline band	1880:1902	higher crystalline band	1880:1902	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	2	118	theme	good	436:439	arg1	solubility					447:456	good water solubility	436:456	good water solubility	436:456	Because Polyvinyl alcohol (PVA) is a synthetic biopolymer with good water solubility and biocompatibility, the composite material formed of CNF and PVA, is a sustainable way of monetizing to address environmental and economic issues.					
37402426	1	119	theme	mechanical	317:326	arg1	properties					328:337	high mechanical properties	312:337	high mechanical properties	312:337	In recent years, production of cellulose nanofiber (CNF) from waste materials has achieved great interest owing to their renewable nature, biodegradability, high mechanical properties, economic value, and low density.					
37402426	15	120	theme	composite	2928:2936	arg1	film					2938:2941	this composite film	2923:2941	this composite film	2923:2941	The size of this composite film may be therefore considered in the range of MF.					
37402426	8	121	theme	band	1899:1902	arg1	presence					1868:1875	the presence	1864:1875	the presence of higher crystalline band in the composite film matrix	1864:1931	The maximum loss rate temperature (Td,max) for PVA/CNF0.5, PVA/CNF1.0, PVA/CNF1.5 was determined by TG analysis to be around 273.4 °C. FTIR studies suggested that PVA/CNF0.5 composite film showed the highest peak at 1428 cm-1 as compared to other PVA/CNF composite films representing the presence of higher crystalline band in the composite film matrix.					
37402426	12	122	theme	significant	2570:2580	arg1	deformation					2582:2592	significant deformation	2570:2592	significant deformation	2570:2592	PVA/CNF0.5 exhibits greater elongation at break (21.7) than the other polymers, indicating a material's ability to undergo significant deformation before failure.					
37402426	11	123	theme	structures	2418:2427	arg1	cyclization					2389:2399	the cyclization	2385:2399	the cyclization of the molecular structures	2385:2427	The maximum young's modulus (111 MPa) was found for PVA/CNF1.0, followed by PVA/CNF0.5, PVA/CNF2.0, PVA/CNF1.5, and pure PVA, which could be attributed to the cyclization of the molecular structures by cross-linking.					
37402426	9	124	theme	membrane	2077:2084	arg1	category					2086:2093	the MF membrane category	2070:2093	the MF membrane category	2070:2093	PVA/CNF0.5 composite film was found to have a surface porosity and mean pore size of 27.35% and 0.19 μm respectively, classifying it in the MF membrane category.					
37402426	6	125	theme	network	1273:1279	arg1	structure					1281:1289	a network structure	1271:1289	a network structure like a tree	1271:1301	The SEM image clearly shows that a network structure like a tree form at the PVA/CNF0.5 composite film, where the sizes and number of pores are apparent.					
37245769	5	0	theme	clathrin-mediated	1143:1159	arg1	endocytosis					1161:1171	clathrin-mediated endocytosis	1143:1171	clathrin-mediated endocytosis	1143:1171	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	1	dep	had	950:952	arg1	enhanced					1086:1093	enhanced	1086:1093	enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis	1086:1171	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	2	theme	bean	1030:1033	arg1	gum					1035:1037	locust bean gum	1023:1037	locust bean gum	1023:1037	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	3	3	theme	mv	790:791	arg1	18.2 ± 0.3 nm					693:705	18.2 ± 0.3 nm	693:705	18.2 ± 0.3 nm	693:705	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	3	theme	mv	790:791	arg1	ZP					772:773	ZP	772:773	ZP of -32.2 ± 0.5 mv	772:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	3	theme	mv	790:791	arg1	PDI					748:750	PDI	748:750	PDI of 0.30 ± 0.04	748:765	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	3	theme	mv	790:791	arg1	EE					728:729	EE	728:729	EE of 70.4 ± 1.6 %	728:745	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	3	theme	mv	790:791	arg1	LC					708:709	LC	708:709	LC of 29.4 ± 0.2 %	708:725	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	4	4	theme	arrangements	902:913	arg1	pattern					881:887	a pattern	879:887	a pattern of staggered arrangements	879:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
37245769	6	5	theme	therapeutic	1200:1210	arg1	effect					1212:1217	an increased therapeutic effect	1187:1217	an increased therapeutic effect	1187:1217	It exhibited an increased therapeutic effect against L.intracellularis in vitro and in vivo.					
37245769	5	6	theme	locust	1023:1028	arg1	gum					1035:1037	locust bean gum	1023:1037	locust bean gum	1023:1037	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	7	theme	TIL	1135:1137	arg1	uptake					1108:1113	the cellular uptake	1095:1113	the cellular uptake	1095:1113	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	7	theme	TIL	1135:1137	arg1	accumulation					1119:1130	accumulation	1119:1130	accumulation of TIL	1119:1137	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	0	8	theme	proliferative	112:124	arg1	enteritis					126:134	porcine proliferative enteritis	104:134	porcine proliferative enteritis caused by Lawsonia intracellularis	104:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	5	9	theme	plain	1047:1051	arg1	nanogels					1053:1060	the plain nanogels	1043:1060	the plain nanogels	1043:1060	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	0	10	theme	porcine	104:110	arg1	enteritis					126:134	porcine proliferative enteritis	104:134	porcine proliferative enteritis caused by Lawsonia intracellularis	104:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	1	11	theme	bioadhesive	375:385	arg1	substances					387:396	bioadhesive substances	375:396	bioadhesive substances	375:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	4	12	from	TIL-nanogels	863:874	arg1	pattern					881:887	a pattern	879:887	a pattern of staggered arrangements	879:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
37245769	5	13	theme	cellular	1099:1106	arg1	uptake					1108:1113	the cellular uptake	1095:1113	the cellular uptake	1095:1113	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	3	14	theme	%	725:725	arg1	18.2 ± 0.3 nm					693:705	18.2 ± 0.3 nm	693:705	18.2 ± 0.3 nm	693:705	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	14	theme	%	725:725	arg1	ZP					772:773	ZP	772:773	ZP of -32.2 ± 0.5 mv	772:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	14	theme	%	725:725	arg1	PDI					748:750	PDI	748:750	PDI of 0.30 ± 0.04	748:765	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	14	theme	%	725:725	arg1	EE					728:729	EE	728:729	EE of 70.4 ± 1.6 %	728:745	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	14	theme	%	725:725	arg1	LC					708:709	LC	708:709	LC of 29.4 ± 0.2 %	708:725	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	0	15	theme	enteritis	126:134	arg1	therapy					93:99	effective therapy	83:99	effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	83:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	3	16	theme	LC	708:709	arg1	diameter					681:688	a diameter	679:688	a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv	679:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	2	17	theme	mass	507:510	arg1	ratio					512:516	a mass ratio	505:516	a mass ratio of 1:1 and CaCl2	505:533	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	1	18	theme	treatment	197:205	arg1	difficulty					207:216	the treatment difficulty	193:216	the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics	193:282	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	3	19	theme	EE	728:729	arg1	diameter					681:688	a diameter	679:688	a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv	679:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	6	20	theme	increased	1190:1198	arg1	effect					1212:1217	an increased therapeutic effect	1187:1217	an increased therapeutic effect	1187:1217	It exhibited an increased therapeutic effect against L.intracellularis in vitro and in vivo.					
37245769	4	21	theme	staggered	892:900	arg1	arrangements					902:913	staggered arrangements	892:913	staggered arrangements	892:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
37245769	0	22	theme	Guar	0:3	arg1	gum					5:7	Guar gum	0:7	Guar gum	0:7	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	4	23	from	pattern	881:887	arg1	surface					852:858	the surface	848:858	the surface of TIL-nanogels in a pattern of staggered arrangements	848:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
37245769	2	24	theme	ionic	541:545	arg1	crosslinker					547:557	an ionic crosslinker	538:557	an ionic crosslinker	538:557	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	24	theme	ionic	541:545	arg1	nanogels					427:434	The optimized nanogels	413:434	The optimized nanogels	413:434	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	3	25	theme	uniform	650:656	arg1	shape					668:672	a uniform spherical shape	648:672	a uniform spherical shape	648:672	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	0	26	theme	tilmicosin-loaded	18:34	arg1	nanogels					70:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels	18:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	18:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	1	27	theme	-loaded	305:311	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	0	28	theme	Lawsonia	146:153	arg1	intracellularis					155:169	Lawsonia intracellularis	146:169	Lawsonia intracellularis	146:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	7	29	theme	intracellular	1328:1340	arg1	infection					1352:1360	intracellular bacterial infection	1328:1360	intracellular bacterial infection treatment	1328:1370	This study will provide guidance for developing nanogels for intracellular bacterial infection treatment.					
37245769	1	30	theme	Lawsonia	221:228	arg1	intracellularis					230:244	Lawsonia intracellularis	221:244	Lawsonia intracellularis (L.intracellularis) using antibiotics	221:282	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	1	30	theme	Lawsonia	221:228	arg1	L.intracellularis					247:263	L.intracellularis	247:263	L.intracellularis	247:263	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	1	31	theme	sodium	313:318	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	1	32	theme	intracellularis	230:244	arg1	difficulty					207:216	the treatment difficulty	193:216	the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics	193:282	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	0	33	theme	alginate/gelatin	43:58	arg1	nanogels					70:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels	18:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	18:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	1	34	theme	alginate	320:327	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	2	35	from	ratio	512:516	arg1	interaction					467:477	electrostatic interaction	453:477	electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2	453:533	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	7	36	theme	bacterial	1342:1350	arg1	infection					1352:1360	intracellular bacterial infection	1328:1360	intracellular bacterial infection treatment	1328:1370	This study will provide guidance for developing nanogels for intracellular bacterial infection treatment.					
37245769	3	37	contain	had	644:646	arg1	TIL-nanogels					614:625	The optimized TIL-nanogels	600:625	The optimized TIL-nanogels modified with GG	600:642	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	37	contain	had	644:646	arg2	shape					668:672	a uniform spherical shape	648:672	a uniform spherical shape	648:672	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	0	38	theme	sodium	36:41	arg1	nanogels					70:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels	18:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	18:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	3	39	theme	PDI	748:750	arg1	diameter					681:688	a diameter	679:688	a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv	679:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	7	40	theme	infection	1352:1360	arg1	treatment					1362:1370	intracellular bacterial infection treatment	1328:1370	intracellular bacterial infection treatment	1328:1370	This study will provide guidance for developing nanogels for intracellular bacterial infection treatment.					
37245769	2	41	theme	CaCl2	529:533	arg1	ratio					512:516	a mass ratio	505:516	a mass ratio of 1:1 and CaCl2	505:533	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	1	42	theme	SA	330:331	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	2	43	mod	modified	571:578	arg3	GG					595:596	GG	595:596	GG	595:596	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	43	mod	modified	571:578	arg1	crosslinker					547:557	an ionic crosslinker	538:557	an ionic crosslinker	538:557	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	43	mod	modified	571:578	arg1	nanogels					427:434	The optimized nanogels	413:434	The optimized nanogels	413:434	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	43	mod	modified	571:578	arg3	gum					590:592	guar gum	585:592	guar gum (GG)	585:597	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	0	44	theme	composite	60:68	arg1	nanogels					70:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels	18:77	tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	18:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	3	45	theme	%	745:745	arg1	18.2 ± 0.3 nm					693:705	18.2 ± 0.3 nm	693:705	18.2 ± 0.3 nm	693:705	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	45	theme	%	745:745	arg1	ZP					772:773	ZP	772:773	ZP of -32.2 ± 0.5 mv	772:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	45	theme	%	745:745	arg1	PDI					748:750	PDI	748:750	PDI of 0.30 ± 0.04	748:765	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	45	theme	%	745:745	arg1	EE					728:729	EE	728:729	EE of 70.4 ± 1.6 %	728:745	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	45	theme	%	745:745	arg1	LC					708:709	LC	708:709	LC of 29.4 ± 0.2 %	708:725	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	46	theme	18.2 ± 0.3 nm	693:705	arg1	diameter					681:688	a diameter	679:688	a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv	679:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	5	47	theme	adhesive	968:975	arg1	strength					977:984	the strongest adhesive strength	954:984	the strongest adhesive strength	954:984	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	48	theme	strongest	958:966	arg1	strength					977:984	the strongest adhesive strength	954:984	the strongest adhesive strength	954:984	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	1	49	theme	/gelatin	333:340	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	2	50	theme	guar	585:588	arg1	GG					595:596	GG	595:596	GG	595:596	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	50	theme	guar	585:588	arg1	gum					590:592	guar gum	585:592	guar gum (GG)	585:597	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	3	51	theme	spherical	658:666	arg1	shape					668:672	a uniform spherical shape	648:672	a uniform spherical shape	648:672	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	4	52	from	surface	852:858	arg1	pattern					881:887	a pattern	879:887	a pattern of staggered arrangements	879:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
37245769	5	53	contain	had	950:952	arg1	TIL-nanogels					920:931	The TIL-nanogels	916:931	The TIL-nanogels modified with GG	916:948	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	5	53	contain	had	950:952	arg2	strength					977:984	the strongest adhesive strength	954:984	the strongest adhesive strength	954:984	The TIL-nanogels modified with GG had the strongest adhesive strength amongst those with I-carrageenan and locust bean gum and the plain nanogels, and thus significantly enhanced the cellular uptake and accumulation of TIL via clathrin-mediated endocytosis.					
37245769	3	54	theme	ZP	772:773	arg1	diameter					681:688	a diameter	679:688	a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv	679:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	0	55	theme	effective	83:91	arg1	therapy					93:99	effective therapy	83:99	effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis	83:169	Guar gum modified tilmicosin-loaded sodium alginate/gelatin composite nanogels for effective therapy of porcine proliferative enteritis caused by Lawsonia intracellularis.					
37245769	3	56	theme	optimized	604:612	arg1	TIL-nanogels					614:625	The optimized TIL-nanogels	600:625	The optimized TIL-nanogels modified with GG	600:642	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	2	57	theme	electrostatic	453:465	arg1	interaction					467:477	electrostatic interaction	453:477	electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2	453:533	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	58	theme	optimized	417:425	arg1	crosslinker					547:557	an ionic crosslinker	538:557	an ionic crosslinker	538:557	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	2	58	theme	optimized	417:425	arg1	nanogels					427:434	The optimized nanogels	413:434	The optimized nanogels	413:434	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	3	59	theme	0.30 ± 0.04	755:765	arg1	18.2 ± 0.3 nm					693:705	18.2 ± 0.3 nm	693:705	18.2 ± 0.3 nm	693:705	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	59	theme	0.30 ± 0.04	755:765	arg1	ZP					772:773	ZP	772:773	ZP of -32.2 ± 0.5 mv	772:791	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	59	theme	0.30 ± 0.04	755:765	arg1	PDI					748:750	PDI	748:750	PDI of 0.30 ± 0.04	748:765	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	59	theme	0.30 ± 0.04	755:765	arg1	EE					728:729	EE	728:729	EE of 70.4 ± 1.6 %	728:745	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	3	59	theme	0.30 ± 0.04	755:765	arg1	LC					708:709	LC	708:709	LC of 29.4 ± 0.2 %	708:725	The optimized TIL-nanogels modified with GG had a uniform spherical shape with a diameter of 18.2 ± 0.3 nm, LC of 29.4 ± 0.2 %, EE of 70.4 ± 1.6 %, PDI of 0.30 ± 0.04, and ZP of -32.2 ± 0.5 mv.					
37245769	2	60	theme	1:1	521:523	arg1	ratio					512:516	a mass ratio	505:516	a mass ratio of 1:1 and CaCl2	505:533	The optimized nanogels were prepared by electrostatic interaction between SA and gelatin at a mass ratio of 1:1 and CaCl2 as an ionic crosslinker and further modified with guar gum (GG).					
37245769	1	61	theme	composite	342:350	arg1	nanogels					352:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels	285:359	the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances	285:396	In order to overcome the treatment difficulty of Lawsonia intracellularis (L.intracellularis) using antibiotics, the tilmicosin (TIL)-loaded sodium alginate (SA)/gelatin composite nanogels modified with bioadhesive substances were designed.					
37245769	4	62	theme	TIL-nanogels	863:874	arg1	surface					852:858	the surface	848:858	the surface of TIL-nanogels in a pattern of staggered arrangements	848:913	The FTIR, DSC, and PXRD showed that GG was covered on the surface of TIL-nanogels in a pattern of staggered arrangements.					
36621333	0	0	theme	antioxidant	104:114	arg1	properties					116:125	excellent antibacterial and antioxidant properties	76:125	excellent antibacterial and antioxidant properties for fruit preservation	76:148	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	1	1	theme	food	341:344	arg1	waste					346:350	considerable food waste	328:350	considerable food waste	328:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	2	2	theme	superior	400:407	arg1	properties					439:448	superior antibacterial and antioxidant properties	400:448	superior antibacterial and antioxidant properties	400:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	3	3	theme	obtained	715:722	arg1	film					751:754	the obtained Chitosan-Tannic acid/MXene film	711:754	the obtained Chitosan-Tannic acid/MXene film	711:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	5	4	theme	packaging	1122:1130	arg1	material					1132:1139	competitive packaging material	1110:1139	competitive packaging material	1110:1139	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	3	5	theme	Chitosan-Tannic	724:738	arg1	film					751:754	the obtained Chitosan-Tannic acid/MXene film	711:754	the obtained Chitosan-Tannic acid/MXene film	711:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	4	6	theme	shelf	930:934	arg1	life					936:939	the shelf life	926:939	the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier	926:1014	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	2	7	theme	hydrogen	529:536	arg1	bonding					538:544	hydrogen bonding	529:544	hydrogen bonding	529:544	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	5	8	theme	fresh	1154:1158	arg1	dilemma					1179:1185	the fresh fruit preservation dilemma	1150:1185	the fresh fruit preservation dilemma	1150:1185	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	5	9	theme	desirable	1023:1031	arg1	performances					1033:1044	These desirable performances	1017:1044	These desirable performances	1017:1044	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	1	10	theme	simple	184:189	arg1	strategy					205:212	a simple and effective strategy	182:212	a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste	182:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	0	11	theme	fruit	131:135	arg1	preservation					137:148	fruit preservation	131:148	fruit preservation	131:148	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	5	12	theme	fruit	1160:1164	arg1	dilemma					1179:1185	the fresh fruit preservation dilemma	1150:1185	the fresh fruit preservation dilemma	1150:1185	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	4	13	theme	composite	888:896	arg1	film					898:901	the composite film	884:901	the composite film	884:901	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	4	14	theme	water	985:989	arg1	vapor					991:995	its excellent water vapor	971:995	its excellent water vapor	971:995	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	4	15	theme	excellent	975:983	arg1	vapor					991:995	its excellent water vapor	971:995	its excellent water vapor	971:995	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	5	16	theme	preservation	1166:1177	arg1	dilemma					1179:1185	the fresh fruit preservation dilemma	1150:1185	the fresh fruit preservation dilemma	1150:1185	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	1	17	theme	effective	195:203	arg1	strategy					205:212	a simple and effective strategy	182:212	a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste	182:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	0	18	theme	Self-assembly	0:12	arg1	fabrication					14:24	Self-assembly fabrication	0:24	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.	0:149	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	5	19	theme	competitive	1110:1120	arg1	material					1132:1139	competitive packaging material	1110:1139	competitive packaging material	1110:1139	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	2	20	theme	composite	380:388	arg1	film					390:393	a biopolymer-based composite film	361:393	a biopolymer-based composite film with superior antibacterial and antioxidant properties	361:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	0	21	theme	chitosan-tannic	29:43	arg1	film					66:69	chitosan-tannic acid/MXene composite film	29:69	chitosan-tannic acid/MXene composite film	29:69	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	5	22	theme	composite	1072:1080	arg1	film					1082:1085	our newly designed composite film	1053:1085	our newly designed composite film	1053:1085	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	5	22	theme	composite	1072:1080	arg1	effective					1096:1104	effective	1096:1104	effective	1096:1104	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	2	23	theme	self-assembly	567:579	arg1	method					581:586	an electrostatic self-assembly method	550:586	an electrostatic self-assembly method	550:586	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	3	24	theme	antibacterial	665:677	arg1	capabilities					695:706	antibacterial and antioxidant capabilities	665:706	antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film	665:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	24	theme	antibacterial	665:677	arg1	properties					626:635	the mechanical properties	611:635	the mechanical properties	611:635	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	2	25	theme	antioxidant	427:437	arg1	properties					439:448	superior antibacterial and antioxidant properties	400:448	superior antibacterial and antioxidant properties	400:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	0	26	theme	composite	56:64	arg1	film					66:69	chitosan-tannic acid/MXene composite film	29:69	chitosan-tannic acid/MXene composite film	29:69	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	5	27	theme	designed	1063:1070	arg1	film					1082:1085	our newly designed composite film	1053:1085	our newly designed composite film	1053:1085	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	5	27	theme	designed	1063:1070	arg1	effective					1096:1104	effective	1096:1104	effective	1096:1104	These desirable performances enable our newly designed composite film to be an effective and competitive packaging material to solve the fresh fruit preservation dilemma.					
36621333	2	28	theme	electrostatic	553:565	arg1	method					581:586	an electrostatic self-assembly method	550:586	an electrostatic self-assembly method	550:586	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	3	29	theme	mechanical	615:624	arg1	capabilities					695:706	antibacterial and antioxidant capabilities	665:706	antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film	665:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	29	theme	mechanical	615:624	arg1	resistance					653:662	heat resistance	648:662	heat resistance	648:662	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	29	theme	mechanical	615:624	arg1	properties					626:635	the mechanical properties	611:635	the mechanical properties	611:635	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	29	theme	mechanical	615:624	arg1	water					638:642	water	638:642	water	638:642	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	0	30	theme	acid/MXene	45:54	arg1	film					66:69	chitosan-tannic acid/MXene composite film	29:69	chitosan-tannic acid/MXene composite film	29:69	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	3	31	theme	scenarios	818:826	arg1	use					796:798	the use	792:798	the use of packaging film scenarios	792:826	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	2	32	theme	tannic	489:494	arg1	acid					496:499	tannic acid	489:499	tannic acid	489:499	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	1	33	theme	shelf	228:232	arg1	life					234:237	the shelf life	224:237	the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste	224:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	4	34	theme	bananas	944:950	arg1	life					936:939	the shelf life	926:939	the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier	926:1014	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	0	35	theme	excellent	76:84	arg1	properties					116:125	excellent antibacterial and antioxidant properties	76:125	excellent antibacterial and antioxidant properties for fruit preservation	76:148	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	0	36	theme	film	66:69	arg1	fabrication					14:24	Self-assembly fabrication	0:24	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.	0:149	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	3	37	theme	packaging	803:811	arg1	scenarios					818:826	packaging film scenarios	803:826	packaging film scenarios	803:826	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	2	38	with	film	390:393	arg1	properties					439:448	superior antibacterial and antioxidant properties	400:448	superior antibacterial and antioxidant properties	400:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	0	39	with	fabrication	14:24	arg1	properties					116:125	excellent antibacterial and antioxidant properties	76:125	excellent antibacterial and antioxidant properties for fruit preservation	76:148	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	3	40	theme	acid/MXene	740:749	arg1	film					751:754	the obtained Chitosan-Tannic acid/MXene film	711:754	the obtained Chitosan-Tannic acid/MXene film	711:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	41	theme	film	813:816	arg1	scenarios					818:826	packaging film scenarios	803:826	packaging film scenarios	803:826	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	4	42	theme	grapes	956:961	arg1	life					936:939	the shelf life	926:939	the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier	926:1014	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	4	43	theme	fruit	833:837	arg1	experiments					852:862	The fruit preservation experiments	829:862	The fruit preservation experiments	829:862	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	3	44	theme	antioxidant	683:693	arg1	capabilities					695:706	antibacterial and antioxidant capabilities	665:706	antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film	665:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	44	theme	antioxidant	683:693	arg1	properties					626:635	the mechanical properties	611:635	the mechanical properties	611:635	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	45	theme	heat	648:651	arg1	resistance					653:662	heat resistance	648:662	heat resistance	648:662	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	45	theme	heat	648:651	arg1	properties					626:635	the mechanical properties	611:635	the mechanical properties	611:635	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	0	46	theme	antibacterial	86:98	arg1	properties					116:125	excellent antibacterial and antioxidant properties	76:125	excellent antibacterial and antioxidant properties for fruit preservation	76:148	Self-assembly fabrication of chitosan-tannic acid/MXene composite film with excellent antibacterial and antioxidant properties for fruit preservation.					
36621333	2	47	theme	antibacterial	409:421	arg1	properties					439:448	superior antibacterial and antioxidant properties	400:448	superior antibacterial and antioxidant properties	400:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	2	48	theme	biopolymer-based	363:378	arg1	film					390:393	a biopolymer-based composite film	361:393	a biopolymer-based composite film with superior antibacterial and antioxidant properties	361:448	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	1	49	theme	time-sensitive	242:255	arg1	fruits					257:262	time-sensitive fruits	242:262	time-sensitive fruits	242:262	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	2	50	theme	chitosan	508:515	arg1	network					517:523	a chitosan network	506:523	a chitosan network via hydrogen bonding and an electrostatic self-assembly method	506:586	Herein, a biopolymer-based composite film with superior antibacterial and antioxidant properties was developed by introducing MXene and tannic acid into a chitosan network via hydrogen bonding and an electrostatic self-assembly method.					
36621333	1	51	theme	considerable	328:339	arg1	waste					346:350	considerable food waste	328:350	considerable food waste	328:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
36621333	4	52	theme	preservation	839:850	arg1	experiments					852:862	The fruit preservation experiments	829:862	The fruit preservation experiments	829:862	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	3	53	theme	film	751:754	arg1	capabilities					695:706	antibacterial and antioxidant capabilities	665:706	antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film	665:754	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	3	53	theme	film	751:754	arg1	properties					626:635	the mechanical properties	611:635	the mechanical properties	611:635	The results show that the mechanical properties, water and heat resistance, antibacterial and antioxidant capabilities of the obtained Chitosan-Tannic acid/MXene film are significantly increased to meet the use of packaging film scenarios.					
36621333	4	54	theme	oxygen	1001:1006	arg1	barrier					1008:1014	oxygen barrier	1001:1014	oxygen barrier	1001:1014	The fruit preservation experiments also confirmed that the composite film can effectively extend the shelf life of bananas and grapes through its excellent water vapor and oxygen barrier.					
36621333	1	55	theme	fruits	257:262	arg1	life					234:237	the shelf life	224:237	the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste	224:350	It is highly urgent to develop a simple and effective strategy to extend the shelf life of time-sensitive fruits, which are very susceptible to spoilage over time, resulting in considerable food waste.					
35107207	8	0	theme	specific	1557:1564	arg1	ability					1576:1582	specific actuating ability	1557:1582	specific actuating ability	1557:1582	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	3	1	theme	solvent	733:739	arg1	system					741:746	an N,N-dimethylformamide solvent system	708:746	system	741:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	1	2	theme	-derived	160:167	arg1	materials					178:186	-derived photonic materials	160:186	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	5	3	from	red	987:989	arg1	variation					972:980	stretchable variation	960:980	stretchable variation from red, yellow, to green responding to the applied mechanical stimuli	960:1052	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	7	4	theme	right-handed	1398:1409	arg1	shapes					1419:1424	right-handed helical shapes	1398:1424	right-handed helical shapes	1398:1424	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	3	5	theme	N	711:711	arg1	system					741:746	an N,N-dimethylformamide solvent system	708:746	system	741:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	6	6	theme	spraying	1092:1099	arg1	moisture					1101:1108	spraying moisture	1092:1108	spraying moisture	1092:1108	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	1	7	theme	photonic	169:176	arg1	materials					178:186	-derived photonic materials	160:186	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	8	8	theme	mechanical	1618:1627	arg1	sensors					1629:1635	mechanical sensors	1618:1635	mechanical sensors	1618:1635	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	7	9	theme	high	1372:1375	arg1	probability					1377:1387	a high probability	1370:1387	a high probability (63%) of right-handed helical shapes	1370:1424	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	7	9	theme	high	1372:1375	arg1	%					1392:1392	63%	1390:1392	63%	1390:1392	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	1	10	dep	nanocrystals	141:152	arg1	materials					178:186	-derived photonic materials	160:186	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	4	11	theme	PEGDMA	772:777	arg1	composite					780:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	8	12	theme	stretchable	1638:1648	arg1	optics					1650:1655	stretchable optics	1638:1655	stretchable optics	1638:1655	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	5	13	theme	optical	928:934	arg1	iridescence					936:946	vivid optical iridescence	922:946	vivid optical iridescence	922:946	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	6	14	theme	complex	1168:1174	arg1	behaviors					1191:1199	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	behaviors	1191:1199	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	2	15	theme	developing	379:388	arg1	sensors					407:413	developing high-performance sensors	379:413	developing high-performance sensors	379:413	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
35107207	5	16	theme	vivid	922:926	arg1	iridescence					936:946	vivid optical iridescence	922:946	vivid optical iridescence	922:946	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	5	17	dep	red	987:989	arg1	yellow					992:997	yellow	992:997	yellow	992:997	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	3	18	theme	ethylene	552:559	arg1	poly					547:550	poly	547:550	poly(ethylene glycol) dimethacrylate (PEGDMA)	547:591	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	18	theme	ethylene	552:559	arg1	glycol					561:566	ethylene glycol	552:566	ethylene glycol	552:566	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	1	19	theme	confirmed	193:201	arg1	potential					209:217	confirmed great potential	193:217	confirmed great potential	193:217	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	0	20	theme	Actuator	110:117	arg1	Properties					119:128	Actuator Properties	110:128	Actuator Properties	110:128	Highly Tough, Stretchable, and Solvent-Resistant Cellulose Nanocrystal Photonic Films for Mechanochromism and Actuator Properties.					
35107207	4	21	theme	impressive	799:808	arg1	42 MPa					820:825	42 MPa	820:825	42 MPa	820:825	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	4	21	theme	impressive	799:808	arg1	strength					810:817	impressive strength	799:817	impressive strength (42 MPa)	799:826	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	8	22	with	system	1496:1501	arg1	ability					1576:1582	specific actuating ability	1557:1582	specific actuating ability	1557:1582	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	22	with	system	1496:1501	arg1	mechanochromism					1536:1550	mechanochromism	1536:1550	mechanochromism	1536:1550	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	22	with	system	1496:1501	arg1	robustness					1524:1533	robustness	1524:1533	robustness	1524:1533	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	22	with	system	1496:1501	arg1	sustainability					1508:1521	sustainability	1508:1521	sustainability	1508:1521	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	7	23	theme	coiled	1439:1444	arg1	tendril					1446:1452	a coiled tendril	1437:1452	a coiled tendril	1437:1452	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	3	24	dep	strategy	533:540	arg1	converged					600:608	converged	600:608	can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	593:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	2	25	theme	intelligent	416:426	arg1	coatings					428:435	intelligent coatings	416:435	intelligent coatings	416:435	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
35107207	7	26	theme	CNC	1289:1291	arg1	anisotropy					1275:1284	its structural anisotropy	1260:1284	its structural anisotropy of CNC with typical left-handedness	1260:1320	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	7	27	with	CNC	1289:1291	arg1	left-handedness					1306:1320	typical left-handedness	1298:1320	typical left-handedness	1298:1320	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	4	28	theme	CNC-poly	763:770	arg1	composite					780:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	8	29	from	avenue	1608:1613	arg1	sensors					1629:1635	mechanical sensors	1618:1635	mechanical sensors	1618:1635	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	29	from	avenue	1608:1613	arg1	optics					1650:1655	stretchable optics	1638:1655	stretchable optics	1638:1655	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	29	from	avenue	1608:1613	arg1	actuators					1670:1678	intelligent actuators	1658:1678	intelligent actuators	1658:1678	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	8	29	from	avenue	1608:1613	arg1	robots					1690:1695	soft robots	1685:1695	soft robots	1685:1695	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	1	30	theme	great	203:207	arg1	potential					209:217	confirmed great potential	193:217	confirmed great potential	193:217	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	3	31	theme	chiral	619:624	arg1	structure					634:642	the chiral nematic structure	615:642	the chiral nematic structure of CNCs	615:650	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	1	32	link	-derived	160:167	arg1	materials					178:186	-derived photonic materials	160:186	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	6	33	theme	actuation	1133:1141	arg1	4.6° s-1					1144:1151	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	4.6° s-1	1144:1151	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	8	34	theme	versatile	1486:1494	arg1	system					1496:1501	this versatile system	1481:1501	this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability	1481:1582	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	2	35	theme	multifunctional	461:475	arg1	devices					477:483	multifunctional devices	461:483	multifunctional devices	461:483	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
35107207	6	36	theme	3D	1176:1177	arg1	behaviors					1191:1199	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	behaviors	1191:1199	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	6	37	theme	multiple	1159:1166	arg1	behaviors					1191:1199	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	behaviors	1191:1199	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	3	38	theme	ultraviolet-triggered	655:675	arg1	polymerization					690:703	ultraviolet-triggered free radical polymerization	655:703	ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	655:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	39	theme	robust	526:531	arg1	strategy					533:540	a facile and robust strategy	513:540	a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	513:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	40	theme	CNCs	647:650	arg1	structure					634:642	the chiral nematic structure	615:642	the chiral nematic structure of CNCs	615:650	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	7	41	theme	typical	1298:1304	arg1	left-handedness					1306:1320	typical left-handedness	1298:1320	typical left-handedness	1298:1320	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	2	42	theme	multiple	356:363	arg1	responses					365:373	multiple responses	356:373	multiple responses	356:373	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
35107207	3	43	theme	free	677:680	arg1	polymerization					690:703	ultraviolet-triggered free radical polymerization	655:703	ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	655:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	8	44	theme	soft	1685:1688	arg1	robots					1690:1695	soft robots	1685:1695	soft robots	1685:1695	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	1	45	contain	have	188:191	arg1	nanocrystals					141:152	Cellulose nanocrystals	131:152	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	1	45	contain	have	188:191	arg2	potential					209:217	confirmed great potential	193:217	confirmed great potential	193:217	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	1	45	contain	have	188:191	arg1	CNCs					155:158	CNCs	155:158	CNCs	155:158	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	6	46	theme	iridescent	1229:1238	arg1	appearances					1240:1250	synergistic iridescent appearances	1217:1250	synergistic iridescent appearances	1217:1250	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	1	47	theme	renewable	232:240	arg1	areas					266:270	renewable optical and engineering areas	232:270	renewable optical and engineering areas	232:270	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	8	48	theme	actuating	1566:1574	arg1	ability					1576:1582	specific actuating ability	1557:1582	specific actuating ability	1557:1582	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	6	49	theme	synergistic	1217:1227	arg1	appearances					1240:1250	synergistic iridescent appearances	1217:1250	synergistic iridescent appearances	1217:1250	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	6	50	theme	sensitive	1123:1131	arg1	4.6° s-1					1144:1151	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	4.6° s-1	1144:1151	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	4	51	theme	solvent	880:886	arg1	resistance					888:897	solvent resistance	880:897	solvent resistance	880:897	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	5	52	theme	applied	1027:1033	arg1	stimuli					1046:1052	the applied mechanical stimuli	1023:1052	the applied mechanical stimuli	1023:1052	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	8	53	theme	sustainable	1596:1606	arg1	avenue					1608:1613	a sustainable avenue	1594:1613	a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots	1594:1695	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	1	54	theme	Cellulose	131:139	arg1	nanocrystals					141:152	Cellulose nanocrystals	131:152	Cellulose nanocrystals (CNCs)-derived photonic materials	131:186	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	1	54	theme	Cellulose	131:139	arg1	CNCs					155:158	CNCs	155:158	CNCs	155:158	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	6	55	theme	deformation	1179:1189	arg1	behaviors					1191:1199	sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors	1123:1199	behaviors	1191:1199	More interestingly, upon exposure to spraying moisture, it executes sensitive actuation (4.6° s-1 ) and multiple complex 3D deformation behaviors, accompanied by synergistic iridescent appearances.					
35107207	5	56	theme	mechanical	1035:1044	arg1	stimuli					1046:1052	the applied mechanical stimuli	1023:1052	the applied mechanical stimuli	1023:1052	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	7	57	theme	helical	1411:1417	arg1	shapes					1419:1424	right-handed helical shapes	1398:1424	right-handed helical shapes	1398:1424	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	4	58	theme	resulting	753:761	arg1	composite					780:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite	749:788	The resulting CNC-poly(PEGDMA) composite exhibits impressive strength (42 MPa), stretchability (104%), toughness (31 MJ m-3 ), and solvent resistance.					
35107207	1	59	theme	optical	242:248	arg1	areas					266:270	renewable optical and engineering areas	232:270	renewable optical and engineering areas	232:270	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	7	60	theme	shapes	1419:1424	arg1	probability					1377:1387	a high probability	1370:1387	a high probability (63%) of right-handed helical shapes	1370:1424	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	7	60	theme	shapes	1419:1424	arg1	%					1392:1392	63%	1390:1392	63%	1390:1392	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	3	61	theme	radical	682:688	arg1	polymerization					690:703	ultraviolet-triggered free radical polymerization	655:703	ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	655:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	5	62	theme	stretchable	960:970	arg1	variation					972:980	stretchable variation	960:980	stretchable variation from red, yellow, to green responding to the applied mechanical stimuli	960:1052	Notably, it preserves vivid optical iridescence, displaying stretchable variation from red, yellow, to green responding to the applied mechanical stimuli.					
35107207	3	63	theme	facile	515:520	arg1	strategy					533:540	a facile and robust strategy	513:540	a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system	513:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	7	64	theme	structural	1264:1273	arg1	anisotropy					1275:1284	its structural anisotropy	1260:1284	its structural anisotropy of CNC with typical left-handedness	1260:1320	Due to its structural anisotropy of CNC with typical left-handedness, the actuation shows the capability to generate a high probability (63%) of right-handed helical shapes, mimicking a coiled tendril.					
35107207	0	65	theme	Photonic	71:78	arg1	Films					80:84	Photonic Films	71:84	Photonic Films	71:84	Highly Tough, Stretchable, and Solvent-Resistant Cellulose Nanocrystal Photonic Films for Mechanochromism and Actuator Properties.					
35107207	2	66	theme	flexible	438:445	arg1	textiles					447:454	flexible textiles	438:454	flexible textiles	438:454	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
35107207	0	67	dep	Tough	7:11	arg1	Films					80:84	Photonic Films	71:84	Photonic Films	71:84	Highly Tough, Stretchable, and Solvent-Resistant Cellulose Nanocrystal Photonic Films for Mechanochromism and Actuator Properties.					
35107207	3	68	theme	poly	547:550	arg1	PEGDMA					585:590	PEGDMA	585:590	PEGDMA	585:590	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	68	theme	poly	547:550	arg1	dimethacrylate					569:582	poly(ethylene glycol) dimethacrylate	547:582	poly(ethylene glycol) dimethacrylate (PEGDMA)	547:591	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	8	69	theme	intelligent	1658:1668	arg1	actuators					1670:1678	intelligent actuators	1658:1678	intelligent actuators	1658:1678	The authors envision that this versatile system with sustainability, robustness, mechanochromism, and specific actuating ability will open a sustainable avenue in mechanical sensors, stretchable optics, intelligent actuators, and soft robots.					
35107207	1	70	theme	engineering	254:264	arg1	areas					266:270	renewable optical and engineering areas	232:270	renewable optical and engineering areas	232:270	Cellulose nanocrystals (CNCs)-derived photonic materials have confirmed great potential in producing renewable optical and engineering areas.					
35107207	3	71	from	polymerization	690:703	arg1	system					741:746	an N,N-dimethylformamide solvent system	708:746	system	741:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	72	theme	N-dimethylformamide	713:731	arg1	system					741:746	an N,N-dimethylformamide solvent system	708:746	system	741:746	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	3	73	theme	nematic	626:632	arg1	structure					634:642	the chiral nematic structure	615:642	the chiral nematic structure of CNCs	615:650	Herein, the authors report a facile and robust strategy that poly(ethylene glycol) dimethacrylate (PEGDMA) can be converged into the chiral nematic structure of CNCs by ultraviolet-triggered free radical polymerization in an N,N-dimethylformamide solvent system.					
35107207	2	74	theme	high-performance	390:405	arg1	sensors					407:413	developing high-performance sensors	379:413	developing high-performance sensors	379:413	However, it remains challenging to simultaneously possess toughness, strength, and multiple responses for developing high-performance sensors, intelligent coatings, flexible textiles, and multifunctional devices.					
37270136	1	0	dep	worldwide	172:180	arg1	turned					182:187	turned	182:187	worldwide turned into a serious preoccupation due to their environmental and health impacts	172:262	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	10	1	theme	antibiotics	1917:1927	arg1	adsorption					1893:1902	the adsorption	1889:1902	the adsorption of the three antibiotics on BC adsorbent	1889:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	7	2	theme	adsorbed	1084:1091	arg1	molecules					1093:1101	adsorbed molecules	1084:1101	adsorbed molecules per site (n)	1084:1114	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	2	3	theme	antibiotic	287:296	arg1	residuals					298:306	antibiotic residuals	287:306	antibiotic residuals	287:306	Since the majority of antibiotic residuals are hardly eliminated from wastewater, based on usual methods, other treatments receive considerable attention.					
37270136	11	4	theme	wastewater	2089:2098	arg1	handling					2100:2107	wastewater handling	2089:2107	wastewater handling	2089:2107	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	5	5	theme	DOR	874:876	arg1	phenomena					889:897	the AMO, AMP, and DOR adsorption phenomena	856:897	the AMO, AMP, and DOR adsorption phenomena	856:897	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	10	6	from	adsorption	1893:1902	arg1	BC					1932:1933	BC adsorbent	1932:1943	BC adsorbent	1932:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	9	7	theme	adsorption	1642:1651	arg1	systems					1653:1659	All adsorption systems	1638:1659	All adsorption systems	1638:1659	All adsorption systems are demonstrated by a calculation of the energy of adsorption, considering that the extrication of these pollutants implies physical interactions.					
37270136	11	8	theme	extract	2006:2012	arg1	antibiotics					2014:2024	extract antibiotics	2006:2024	extract antibiotics	2006:2024	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	2	9	theme	considerable	396:407	arg1	attention					409:417	considerable attention	396:417	considerable attention	396:417	Since the majority of antibiotic residuals are hardly eliminated from wastewater, based on usual methods, other treatments receive considerable attention.					
37270136	8	10	theme	adsorption	1559:1568	arg1	capacities					1570:1579	the adsorption capacities	1555:1579	the adsorption capacities	1555:1579	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	11	11	theme	important	2050:2058	arg1	sample					1959:1964	BC sample	1956:1964	BC sample	1956:1964	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	11	theme	important	2050:2058	arg1	adsorbent					1993:2001	adsorbent	1993:2001	adsorbent	1993:2001	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	11	theme	important	2050:2058	arg1	potentials					2060:2069	important potentials	2050:2069	important potentials	2050:2069	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	12	theme	BC	1956:1957	arg1	sample					1959:1964	BC sample	1956:1964	BC sample	1956:1964	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	12	theme	BC	1956:1957	arg1	adsorbent					1993:2001	adsorbent	1993:2001	adsorbent	1993:2001	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	12	theme	BC	1956:1957	arg1	potentials					2060:2069	important potentials	2050:2069	important potentials	2050:2069	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	1	13	theme	antibiotics	160:170	arg1	use					153:155	The increased use	139:155	The increased use of antibiotics	139:170	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	8	14	theme	adsorption	1255:1264	arg1	70.4-88.0 mg/g					1357:1370	70.4-88.0 mg/g	1357:1370	70.4-88.0 mg/g	1357:1370	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	8	14	theme	adsorption	1255:1264	arg1	amounts					1266:1272	The adsorption amounts	1251:1272	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model,	1251:1339	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	0	15	theme	physical	89:96	arg1	investigation					98:110	physical investigation	89:110	physical investigation	89:110	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	16	theme	adsorption	521:530	arg1	isotherms					532:540	the adsorption isotherms	517:540	the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite	517:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	4	17	theme	physics	791:797	arg1	theory					799:804	a statistical physics theory	777:804	a statistical physics theory	777:804	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	0	18	theme	adsorption	119:128	arg1	process					130:136	the adsorption process	115:136	the adsorption process	115:136	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	19	theme	phenomenon	756:765	arg1	investigation					727:739	a theoretical investigation	713:739	a theoretical investigation of the removal phenomenon	713:765	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	7	20	theme	multi-docking	1138:1150	arg1	phenomena					1188:1196	multi-docking (n < 1) and multi-molecular (n > 1) phenomena	1138:1196	multi-docking (n < 1) and multi-molecular (n > 1) phenomena	1138:1196	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	4	21	used	used	697:700	arg2	T = 303.15					654:663	T = 303.15	654:663	T = 303.15	654:663	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	4	21	used	used	697:700	arg2	temperatures					640:651	three temperatures	634:651	three temperatures	634:651	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	4	21	used	used	697:700	arg2	323.15 K					677:684	323.15 K	677:684	323.15 K	677:684	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	4	21	used	used	697:700	arg2	313.15					666:671	313.15	666:671	313.15	666:671	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	8	22	theme	antibiotics	1472:1482	arg1	performance					1495:1505	the antibiotics adsorption performance	1468:1505	the antibiotics adsorption performance of BC	1468:1511	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	7	23	dep	multi-molecular	1164:1178	arg1	n > 1					1181:1185	n > 1	1181:1185	n > 1	1181:1185	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	0	24	theme	antibiotics	14:24	arg1	Adsorption					0:9	Adsorption	0:9	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.	0:137	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	25	theme	amoxicillin	572:582	arg1	isotherms					532:540	the adsorption isotherms	517:540	the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite	517:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	0	26	theme	bentonite-chitosan	29:46	arg1	composite					48:56	bentonite-chitosan composite	29:56	bentonite-chitosan composite	29:56	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	7	27	theme	DOR	1229:1231	arg1	adsorption					1233:1242	DOR adsorption	1229:1242	DOR adsorption on BC	1229:1248	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	8	28	theme	BC	1510:1511	arg1	performance					1495:1505	the antibiotics adsorption performance	1468:1505	the antibiotics adsorption performance of BC	1468:1511	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	8	29	theme	monolayer	1324:1332	arg1	model					1334:1338	the monolayer model	1320:1338	the monolayer model	1320:1338	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	5	30	theme	analytical	813:822	arg1	models					824:829	Three analytical models	807:829	Three analytical models	807:829	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	5	31	used	utilized	835:842	arg2	models					824:829	Three analytical models	807:829	Three analytical models	807:829	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	7	32	from	adsorption	1233:1242	arg1	BC					1247:1248	BC	1247:1248	BC	1247:1248	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	8	33	from	saturation	1277:1286	arg1	70.4-88.0 mg/g					1357:1370	70.4-88.0 mg/g	1357:1370	70.4-88.0 mg/g	1357:1370	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	8	33	from	saturation	1277:1286	arg1	amounts					1266:1272	The adsorption amounts	1251:1272	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model,	1251:1339	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	0	34	dep	Adsorption	0:9	arg1	modeling					76:83	Phenomenological modeling	59:83	Phenomenological modeling	59:83	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	0	34	dep	Adsorption	0:9	arg1	investigation					98:110	physical investigation	89:110	physical investigation	89:110	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	35	from	isotherms	532:540	arg1	composite					606:614	bentonite-chitosan composite	587:614	bentonite-chitosan composite	587:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	2	36	theme	other	371:375	arg1	treatments					377:386	other treatments	371:386	other treatments	371:386	Since the majority of antibiotic residuals are hardly eliminated from wastewater, based on usual methods, other treatments receive considerable attention.					
37270136	8	37	theme	operating	1618:1626	arg1	variable					1628:1635	this operating variable	1613:1635	this operating variable	1613:1635	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	4	38	theme	bentonite-chitosan	587:604	arg1	composite					606:614	bentonite-chitosan composite	587:614	bentonite-chitosan composite	587:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	7	39	theme	molecules	1093:1101	arg1	number					1074:1079	the number	1070:1079	the number of adsorbed molecules per site (n)	1070:1114	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	2	40	theme	residuals	298:306	arg1	majority					275:282	the majority	271:282	the majority of antibiotic residuals	271:306	Since the majority of antibiotic residuals are hardly eliminated from wastewater, based on usual methods, other treatments receive considerable attention.					
37270136	5	41	theme	AMP	865:867	arg1	phenomena					889:897	the AMO, AMP, and DOR adsorption phenomena	856:897	the AMO, AMP, and DOR adsorption phenomena	856:897	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	11	42	theme	industrial	2112:2121	arg1	level					2123:2127	industrial level	2112:2127	industrial level	2112:2127	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	7	43	from	AMO	1215:1217	arg1	BC					1247:1248	BC	1247:1248	BC	1247:1248	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	1	44	theme	serious	196:202	arg1	preoccupation					204:216	a serious preoccupation	194:216	a serious preoccupation due to their environmental and health impacts	194:262	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	10	45	from	nature	1879:1884	arg1	BC					1932:1933	BC adsorbent	1932:1943	BC adsorbent	1932:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	7	46	from	AMP	1220:1222	arg1	BC					1247:1248	BC	1247:1248	BC	1247:1248	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	10	47	theme	adsorbent	1935:1943	arg1	BC					1932:1933	BC adsorbent	1932:1943	BC adsorbent	1932:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	1	48	theme	due	218:220	arg1	preoccupation					204:216	a serious preoccupation	194:216	a serious preoccupation due to their environmental and health impacts	194:262	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	6	49	theme	antibiotic	953:962	arg1	adsorption					964:973	all antibiotic adsorption	949:973	all antibiotic adsorption on a BC adsorbent	949:991	From the fitting results, all antibiotic adsorption on a BC adsorbent is associated with the monolayer formation with one type of site.					
37270136	5	50	theme	AMO	860:862	arg1	phenomena					889:897	the AMO, AMP, and DOR adsorption phenomena	856:897	the AMO, AMP, and DOR adsorption phenomena	856:897	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	8	51	theme	BC	1295:1296	arg1	saturation					1277:1286	saturation	1277:1286	saturation of the BC adsorbent, deduced by the monolayer model,	1277:1339	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	5	52	theme	molecular	906:914	arg1	level					916:920	the molecular level	902:920	the molecular level	902:920	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	6	53	theme	fitting	932:938	arg1	results					940:946	the fitting results	928:946	the fitting results	928:946	From the fitting results, all antibiotic adsorption on a BC adsorbent is associated with the monolayer formation with one type of site.					
37270136	4	54	theme	theoretical	715:725	arg1	investigation					727:739	a theoretical investigation	713:739	a theoretical investigation of the removal phenomenon	713:765	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	1	55	theme	increased	143:151	arg1	use					153:155	The increased use	139:155	The increased use of antibiotics	139:170	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	6	56	theme	monolayer	1016:1024	arg1	formation					1026:1034	the monolayer formation	1012:1034	the monolayer formation	1012:1034	From the fitting results, all antibiotic adsorption on a BC adsorbent is associated with the monolayer formation with one type of site.					
37270136	5	57	theme	adsorption	878:887	arg1	phenomena					889:897	the AMO, AMP, and DOR adsorption phenomena	856:897	the AMO, AMP, and DOR adsorption phenomena	856:897	Three analytical models are utilized to describe the AMO, AMP, and DOR adsorption phenomena at the molecular level.					
37270136	9	58	theme	energy	1702:1707	arg1	calculation					1683:1693	a calculation	1681:1693	a calculation of the energy of adsorption	1681:1721	All adsorption systems are demonstrated by a calculation of the energy of adsorption, considering that the extrication of these pollutants implies physical interactions.					
37270136	7	59	theme	multi-molecular	1164:1178	arg1	phenomena					1188:1196	multi-docking (n < 1) and multi-molecular (n > 1) phenomena	1138:1196	multi-docking (n < 1) and multi-molecular (n > 1) phenomena	1138:1196	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	10	60	from	BC	1932:1933	arg1	nature					1879:1884	the spontaneous and feasible nature	1850:1884	the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent	1850:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	9	61	theme	adsorption	1712:1721	arg1	energy					1702:1707	the energy	1698:1707	the energy of adsorption	1698:1721	All adsorption systems are demonstrated by a calculation of the energy of adsorption, considering that the extrication of these pollutants implies physical interactions.					
37270136	7	62	dep	multi-docking	1138:1150	arg1	n < 1					1153:1157	n < 1	1153:1157	n < 1	1153:1157	Concerning the number of adsorbed molecules per site (n), it is concluded that multi-docking (n < 1) and multi-molecular (n > 1) phenomena are feasible for AMO, AMP, and DOR adsorption on BC.					
37270136	11	63	from	water	2031:2035	arg1	sample					1959:1964	BC sample	1956:1964	BC sample	1956:1964	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	63	from	water	2031:2035	arg1	adsorbent					1993:2001	adsorbent	1993:2001	adsorbent	1993:2001	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	11	63	from	water	2031:2035	arg1	potentials					2060:2069	important potentials	2050:2069	important potentials	2050:2069	In brief, BC sample is regarded as a promising adsorbent to extract antibiotics from water and presents important potentials to be effected in wastewater handling at industrial level.					
37270136	0	64	theme	process	130:136	arg1	modeling					76:83	Phenomenological modeling	59:83	Phenomenological modeling	59:83	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	0	64	theme	process	130:136	arg1	investigation					98:110	physical investigation	89:110	physical investigation	89:110	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	65	theme	statistical	779:789	arg1	theory					799:804	a statistical physics theory	777:804	a statistical physics theory	777:804	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	6	66	theme	site	1053:1056	arg1	type					1045:1048	one type	1041:1048	one type of site	1041:1056	From the fitting results, all antibiotic adsorption on a BC adsorbent is associated with the monolayer formation with one type of site.					
37270136	8	67	theme	adsorption	1484:1493	arg1	performance					1495:1505	the antibiotics adsorption performance	1468:1505	the antibiotics adsorption performance of BC	1468:1511	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	4	68	theme	removal	748:754	arg1	phenomenon					756:765	the removal phenomenon	744:765	the removal phenomenon	744:765	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	3	69	theme	effective	452:460	arg1	method					462:467	the most effective method	443:467	the most effective method of the treatment of antibiotics	443:499	Adsorption is known as the most effective method of the treatment of antibiotics.					
37270136	3	69	theme	effective	452:460	arg1	Adsorption					420:429	Adsorption	420:429	Adsorption	420:429	Adsorption is known as the most effective method of the treatment of antibiotics.					
37270136	9	70	theme	pollutants	1766:1775	arg1	extrication					1745:1755	the extrication	1741:1755	the extrication of these pollutants	1741:1775	All adsorption systems are demonstrated by a calculation of the energy of adsorption, considering that the extrication of these pollutants implies physical interactions.					
37270136	8	71	theme	adsorbent	1298:1306	arg1	BC					1295:1296	the BC adsorbent	1291:1306	the BC adsorbent	1291:1306	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37270136	3	72	theme	antibiotics	489:499	arg1	treatment					476:484	the treatment	472:484	the treatment of antibiotics	472:499	Adsorption is known as the most effective method of the treatment of antibiotics.					
37270136	9	73	theme	physical	1785:1792	arg1	interactions					1794:1805	physical interactions	1785:1805	physical interactions	1785:1805	All adsorption systems are demonstrated by a calculation of the energy of adsorption, considering that the extrication of these pollutants implies physical interactions.					
37270136	4	74	theme	doripenem	545:553	arg1	isotherms					532:540	the adsorption isotherms	517:540	the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite	517:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	6	75	from	adsorption	964:973	arg1	adsorbent					983:991	adsorbent	983:991	adsorbent	983:991	From the fitting results, all antibiotic adsorption on a BC adsorbent is associated with the monolayer formation with one type of site.					
37270136	10	76	theme	thermodynamic	1812:1824	arg1	interpretation					1826:1839	The thermodynamic interpretation	1808:1839	The thermodynamic interpretation	1808:1839	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	3	77	theme	treatment	476:484	arg1	method					462:467	the most effective method	443:467	the most effective method of the treatment of antibiotics	443:499	Adsorption is known as the most effective method of the treatment of antibiotics.					
37270136	3	77	theme	treatment	476:484	arg1	Adsorption					420:429	Adsorption	420:429	Adsorption	420:429	Adsorption is known as the most effective method of the treatment of antibiotics.					
37270136	0	78	theme	Phenomenological	59:74	arg1	modeling					76:83	Phenomenological modeling	59:83	Phenomenological modeling	59:83	Adsorption of antibiotics by bentonite-chitosan composite: Phenomenological modeling and physical investigation of the adsorption process.					
37270136	4	79	theme	ampicillin	556:565	arg1	isotherms					532:540	the adsorption isotherms	517:540	the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite	517:614	In this paper, the adsorption isotherms of doripenem, ampicillin, and amoxicillin on bentonite-chitosan composite are determined at three temperatures, T = 303.15, 313.15 and 323.15 K, which are used to achieve a theoretical investigation of the removal phenomenon, based on a statistical physics theory.					
37270136	10	80	theme	feasible	1870:1877	arg1	nature					1879:1884	the spontaneous and feasible nature	1850:1884	the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent	1850:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	2	81	theme	usual	356:360	arg1	methods					362:368	usual methods	356:368	usual methods	356:368	Since the majority of antibiotic residuals are hardly eliminated from wastewater, based on usual methods, other treatments receive considerable attention.					
37270136	10	82	theme	spontaneous	1854:1864	arg1	nature					1879:1884	the spontaneous and feasible nature	1850:1884	the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent	1850:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	1	83	theme	health	249:254	arg1	impacts					256:262	their environmental and health impacts	225:262	impacts	256:262	The increased use of antibiotics worldwide turned into a serious preoccupation due to their environmental and health impacts.					
37270136	10	84	theme	adsorption	1893:1902	arg1	nature					1879:1884	the spontaneous and feasible nature	1850:1884	the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent	1850:1943	The thermodynamic interpretation confirms the spontaneous and feasible nature of the adsorption of the three antibiotics on BC adsorbent.					
37270136	8	85	theme	variable	1628:1635	arg1	increment					1600:1608	the increment	1596:1608	the increment of this operating variable	1596:1635	The adsorption amounts at saturation of the BC adsorbent, deduced by the monolayer model, are found to be 70.4-88.0 mg/g for doripenem, 57.8-79.2 mg/g for ampicillin and 38.6-67.5 mg/g for amoxicillin indicating that the antibiotics adsorption performance of BC was greatly depended on temperature where the adsorption capacities increased with the increment of this operating variable.					
37119624	13	0	theme	suggested	1752:1760	arg1	approach					1762:1769	the suggested approach	1748:1769	the suggested approach	1748:1769	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	11	1	theme	research	1481:1488	arg1	study					1490:1494	this research study	1476:1494	this research study	1476:1494	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	1	2	theme	detrimental	245:255	arg1	effects					271:277	the detrimental environmental effects	241:277	the detrimental environmental effects of synthetic plastics	241:299	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	4	3	theme	starch	589:594	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	5	4	theme	plastics	650:657	arg1	value					641:645	the value	637:645	the value of plastics	637:657	People have discovered the value of plastics all around the world.					
37119624	6	5	theme	restaurant	766:775	arg1	products					777:784	throwaway quick service restaurant products	742:784	throwaway quick service restaurant products	742:784	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	7	6	theme	negative	819:826	arg1	dumping					854:860	their dumping	848:860	their dumping	848:860	Regarding the negative aspect of plastics, their dumping after durability poses a serious risk to both people and wildlife.					
37119624	7	6	theme	negative	819:826	arg1	aspect					828:833	the negative aspect	815:833	the negative aspect of plastics	815:845	Regarding the negative aspect of plastics, their dumping after durability poses a serious risk to both people and wildlife.					
37119624	11	7	theme	Fuzzy	1357:1361	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	6	8	theme	quick	752:756	arg1	products					777:784	throwaway quick service restaurant products	742:784	throwaway quick service restaurant products	742:784	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	13	9	theme	plastic	1685:1691	arg1	synthesis					1693:1701	biodegradable dynamic plastic synthesis	1663:1701	biodegradable dynamic plastic synthesis	1663:1701	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	12	10	theme	criteria	1533:1540	arg1	weights					1518:1524	the objective weights	1504:1524	the objective weights of the criteria in this case	1504:1553	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	8	11	theme	alternative	963:973	arg1	resources					983:991	alternative natural resources	963:991	alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable	963:1087	This prompted researchers to seek alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable.					
37119624	11	12	used	utilized	1464:1471	arg2	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	13	theme	set-based	107:115	arg1	method					124:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	9	14	theme	flexible	1166:1173	arg1	biopolymers					1175:1185	flexible biopolymers	1166:1185	flexible biopolymers	1166:1185	It has been discovered that tuber and grain starches can be used to produce flexible biopolymers.					
37119624	14	15	theme	thermoplastic	1816:1828	arg1	starches					1830:1837	thermoplastic starches	1816:1837	thermoplastic starches derived from rice and corn for packaging applications	1816:1891	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	12	16	theme	objective	1508:1516	arg1	weights					1518:1524	the objective weights	1504:1524	the objective weights of the criteria in this case	1504:1553	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	13	17	theme	biodegradable	1663:1675	arg1	synthesis					1693:1701	biodegradable dynamic plastic synthesis	1663:1701	biodegradable dynamic plastic synthesis	1663:1701	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	10	18	dep	problem	1251:1257	arg1	have					1306:1309	have	1306:1309	have varying qualities	1306:1327	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	10	19	theme	MCDM	1246:1249	arg1	decision					1192:1199	The decision to choose the best among these choices	1188:1238	The decision to choose the best among these choices	1188:1238	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	10	19	theme	MCDM	1246:1249	arg1	problem					1251:1257	an MCDM problem	1243:1257	an MCDM problem because the carbohydrates from these suppliers have varying qualities	1243:1327	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	0	20	theme	dynamic	51:57	arg1	product					67:73	a biodegradable dynamic plastic product	35:73	a biodegradable dynamic plastic product	35:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	0	21	dep	method	124:129	arg1	approach					13:20	A novel MCDM approach	0:20	A novel MCDM approach to selecting a biodegradable dynamic plastic product	0:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	4	22	theme	samples	507:513	arg1	types					487:491	Several types	479:491	Several types of bioplastic samples	479:513	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	1	23	theme	biodegradable	151:163	arg1	polymers					165:172	biodegradable polymers	151:172	biodegradable polymers for both industrial and commercial uses	151:212	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	8	24	used	used	1005:1008	arg2	resources					983:991	alternative natural resources	963:991	alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable	963:1087	This prompted researchers to seek alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable.					
37119624	4	25	theme	Several	479:485	arg1	types					487:491	Several types	479:491	Several types of bioplastic samples	479:513	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	9	26	used	used	1150:1153	arg2	starches					1134:1141	tuber and grain starches	1118:1141	tuber and grain starches	1118:1141	It has been discovered that tuber and grain starches can be used to produce flexible biopolymers.					
37119624	11	27	theme	COmplex	1380:1386	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	28	theme	hesitant	92:99	arg1	method					124:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	12	29	used	used	1559:1562	arg2	we					1556:1557	we	1556:1557	we	1556:1557	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	12	30	theme	weight	1585:1590	arg1	determination					1592:1604	weight determination	1585:1604	weight determination	1585:1604	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	3	31	theme	current	388:394	arg1	study					396:400	The current study	384:400	The current study	384:400	The current study examines bioplastics made from maize and rice starch for packaging purposes.					
37119624	11	32	theme	COPRAS	1413:1418	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	33	theme	MCDM	8:11	arg1	approach					13:20	A novel MCDM approach	0:20	A novel MCDM approach to selecting a biodegradable dynamic plastic product	0:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	1	34	theme	plastics	292:299	arg1	effects					271:277	the detrimental environmental effects	241:277	the detrimental environmental effects of synthetic plastics	241:299	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	11	35	theme	ASsessment	1401:1410	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	4	36	theme	various	533:539	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	10	37	contain	have	1306:1309	arg1	carbohydrates					1271:1283	the carbohydrates	1267:1283	the carbohydrates from these suppliers	1267:1304	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	10	37	contain	have	1306:1309	arg2	qualities					1319:1327	varying qualities	1311:1327	varying qualities	1311:1327	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	6	38	theme	trash	711:715	arg1	bags					717:720	trash bags	711:720	trash bags	711:720	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	6	39	theme	other	791:795	arg1	things					797:802	other things	791:802	other things	791:802	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	14	40	theme	packaging	1870:1878	arg1	applications					1880:1891	packaging applications	1870:1891	packaging applications	1870:1891	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	4	41	theme	rice	601:604	arg1	starch					606:611	rice starch	601:611	rice starch	601:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	9	42	theme	tuber	1118:1122	arg1	starches					1134:1141	tuber and grain starches	1118:1141	tuber and grain starches	1118:1141	It has been discovered that tuber and grain starches can be used to produce flexible biopolymers.					
37119624	2	43	theme	numerous	350:357	arg1	composites					372:381	numerous starch-based composites	350:381	numerous starch-based composites	350:381	For a variety of uses, researchers have created numerous starch-based composites.					
37119624	4	44	theme	acid	577:580	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	11	45	theme	Set	1363:1365	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	9	46	theme	grain	1128:1132	arg1	starches					1134:1141	tuber and grain starches	1118:1141	tuber and grain starches	1118:1141	It has been discovered that tuber and grain starches can be used to produce flexible biopolymers.					
37119624	7	47	theme	plastics	838:845	arg1	dumping					854:860	their dumping	848:860	their dumping	848:860	Regarding the negative aspect of plastics, their dumping after durability poses a serious risk to both people and wildlife.					
37119624	7	47	theme	plastics	838:845	arg1	aspect					828:833	the negative aspect	815:833	the negative aspect of plastics	815:845	Regarding the negative aspect of plastics, their dumping after durability poses a serious risk to both people and wildlife.					
37119624	1	48	theme	environmental	257:269	arg1	effects					271:277	the detrimental environmental effects	241:277	the detrimental environmental effects of synthetic plastics	241:299	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	4	49	theme	maize	583:587	arg1	starch					589:594	maize starch	583:594	maize starch	583:594	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	11	50	theme	Hesitant	1348:1355	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	6	51	theme	service	758:764	arg1	products					777:784	throwaway quick service restaurant products	742:784	throwaway quick service restaurant products	742:784	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	1	52	theme	polymers	165:172	arg1	development					136:146	The development	132:146	The development of biodegradable polymers for both industrial and commercial uses	132:212	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	1	52	theme	polymers	165:172	arg1	crucial					217:223	crucial	217:223	crucial	217:223	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	1	52	theme	polymers	165:172	arg1	nowadays					225:232	nowadays	225:232	nowadays	225:232	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	13	53	theme	dynamic	1677:1683	arg1	synthesis					1693:1701	biodegradable dynamic plastic synthesis	1663:1701	biodegradable dynamic plastic synthesis	1663:1701	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	6	54	theme	throwaway	742:750	arg1	products					777:784	throwaway quick service restaurant products	742:784	throwaway quick service restaurant products	742:784	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	8	55	theme	natural	975:981	arg1	resources					983:991	alternative natural resources	963:991	alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable	963:1087	This prompted researchers to seek alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable.					
37119624	0	56	theme	COPRAS	117:122	arg1	method					124:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	13	57	theme	optimal	1640:1646	arg1	hydrolyzes					1648:1657	the optimal hydrolyzes	1636:1657	the optimal hydrolyzes for biodegradable dynamic plastic synthesis	1636:1701	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	14	58	theme	starches	1830:1837	arg1	feasibility					1801:1811	the feasibility	1797:1811	the feasibility of thermoplastic starches derived from rice and corn for packaging applications	1797:1891	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	1	59	dep	crucial	217:223	arg1	development					136:146	The development	132:146	The development of biodegradable polymers for both industrial and commercial uses	132:212	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	1	59	dep	crucial	217:223	arg1	crucial					217:223	crucial	217:223	crucial	217:223	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	1	59	dep	crucial	217:223	arg1	nowadays					225:232	nowadays	225:232	nowadays	225:232	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	6	60	used	used	691:694	arg2	It					681:682	It	681:682	It	681:682	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	0	61	theme	plastic	59:65	arg1	product					67:73	a biodegradable dynamic plastic product	35:73	a biodegradable dynamic plastic product	35:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	12	62	theme	determination	1592:1604	arg1	method					1575:1580	the Critic method	1564:1580	the Critic method of weight determination	1564:1604	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	11	63	theme	uncertainty	1440:1450	arg1	problems					1452:1459	uncertainty problems	1440:1459	uncertainty problems	1440:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	64	theme	probabilistic	78:90	arg1	method					124:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	11	65	theme	-based	1373:1378	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	66	theme	fuzzy	101:105	arg1	method					124:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	a probabilistic hesitant fuzzy set-based COPRAS method	76:129	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	12	67	theme	Critic	1568:1573	arg1	method					1575:1580	the Critic method	1564:1580	the Critic method of weight determination	1564:1604	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	4	68	theme	bioplastic	496:505	arg1	samples					507:513	bioplastic samples	496:513	bioplastic samples	496:513	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	11	69	theme	PHFS	1368:1371	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	0	70	theme	novel	2:6	arg1	approach					13:20	A novel MCDM approach	0:20	A novel MCDM approach to selecting a biodegradable dynamic plastic product	0:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	8	71	theme	flexible	1020:1027	arg1	polymers					1029:1036	flexible polymers	1020:1036	flexible polymers that are recyclable, eco-friendly, and sustainable	1020:1087	This prompted researchers to seek alternative natural resources that may be used to create flexible polymers that are recyclable, eco-friendly, and sustainable.					
37119624	4	72	theme	glycerol	560:567	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	13	73	theme	example	1610:1616	arg1	case					1618:1621	An example case	1607:1621	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis	1607:1701	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	13	74	theme	approach	1762:1769	arg1	applicability					1731:1743	the applicability	1727:1743	the applicability of the suggested approach	1727:1769	An example case of selecting the optimal hydrolyzes for biodegradable dynamic plastic synthesis was chosen to represent the applicability of the suggested approach.					
37119624	1	75	theme	synthetic	282:290	arg1	plastics					292:299	synthetic plastics	282:299	synthetic plastics	282:299	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	7	76	theme	serious	887:893	arg1	risk					895:898	a serious risk	885:898	a serious risk to both people and wildlife	885:926	Regarding the negative aspect of plastics, their dumping after durability poses a serious risk to both people and wildlife.					
37119624	10	77	from	suppliers	1296:1304	arg1	carbohydrates					1271:1283	the carbohydrates	1267:1283	the carbohydrates from these suppliers	1267:1304	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	4	78	theme	citric	570:575	arg1	acid					577:580	citric acid	570:580	citric acid	570:580	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	11	79	theme	PRoportional	1388:1399	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	3	80	dep	maize	433:437	arg1	starch					448:453	starch	448:453	starch	448:453	The current study examines bioplastics made from maize and rice starch for packaging purposes.					
37119624	1	81	dep	industrial	183:192	arg1	uses					209:212	uses	209:212	uses	209:212	The development of biodegradable polymers for both industrial and commercial uses is crucial nowadays due to the detrimental environmental effects of synthetic plastics.					
37119624	6	82	theme	liquid	723:728	arg1	containers					730:739	liquid containers	723:739	liquid containers	723:739	It can be used for packaging, trash bags, liquid containers, throwaway quick service restaurant products, and other things.					
37119624	3	83	theme	packaging	459:467	arg1	purposes					469:476	packaging purposes	459:476	packaging purposes	459:476	The current study examines bioplastics made from maize and rice starch for packaging purposes.					
37119624	0	84	theme	biodegradable	37:49	arg1	product					67:73	a biodegradable dynamic plastic product	35:73	a biodegradable dynamic plastic product	35:73	A novel MCDM approach to selecting a biodegradable dynamic plastic product: a probabilistic hesitant fuzzy set-based COPRAS method.					
37119624	4	85	theme	gelatin	551:557	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	12	86	from	weights	1518:1524	arg1	case					1550:1553	this case	1545:1553	this case	1545:1553	To get the objective weights of the criteria in this case, we used the Critic method of weight determination.					
37119624	14	87	attach	derived	1839:1845	arg1	corn					1861:1864	corn	1861:1864	corn	1861:1864	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	14	87	attach	derived	1839:1845	arg1	rice					1852:1855	rice	1852:1855	rice	1852:1855	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	14	87	attach	derived	1839:1845	arg2	starches					1830:1837	thermoplastic starches	1816:1837	thermoplastic starches derived from rice and corn for packaging applications	1816:1891	The findings demonstrate the feasibility of thermoplastic starches derived from rice and corn for packaging applications.					
37119624	10	88	theme	varying	1311:1317	arg1	qualities					1319:1327	varying qualities	1311:1327	varying qualities	1311:1327	The decision to choose the best among these choices is an MCDM problem because the carbohydrates from these suppliers have varying qualities.					
37119624	2	89	theme	uses	319:322	arg1	uses					319:322	uses	319:322	uses	319:322	For a variety of uses, researchers have created numerous starch-based composites.					
37119624	2	89	theme	uses	319:322	arg1	variety					308:314	a variety	306:314	a variety of uses	306:322	For a variety of uses, researchers have created numerous starch-based composites.					
37119624	4	90	theme	starch	606:611	arg1	ratios					541:546	various ratios	533:546	various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch	533:611	Several types of bioplastic samples are created using various ratios of gelatin, glycerol, citric acid, maize starch, and rice starch.					
37119624	11	91	theme	Probabilistic	1334:1346	arg1	method					1421:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method	1330:1426	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems	1330:1459	The Probabilistic Hesitant Fuzzy Set (PHFS)-based COmplex PRoportional ASsessment (COPRAS) method for solving uncertainty problems is utilized in this research study.					
37119624	2	92	theme	starch-based	359:370	arg1	composites					372:381	numerous starch-based composites	350:381	numerous starch-based composites	350:381	For a variety of uses, researchers have created numerous starch-based composites.					
34999488	11	0	theme	elastic	1675:1681	arg1	modulus					1683:1689	an average elastic modulus	1664:1689	an average elastic modulus of 287.5 ± 62.6 MPa	1664:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	6	1	theme	sweep	853:857	arg1	tests					859:863	Frequency sweep tests	843:863	Frequency sweep tests	843:863	Frequency sweep tests were conducted on eight porcine meniscal specimens.					
34999488	12	2	theme	water	1815:1819	arg1	content					1821:1827	tissue water content	1808:1827	tissue water content	1808:1827	Magnitudes of the mechanical parameters governing the ECM and fibers were negatively related to tissue water content.					
34999488	11	3	theme	element	1567:1573	arg1	analysis					1575:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	3	4	theme	pertinent	549:557	arg1	properties					570:579	the tissue's pertinent mechanical properties	536:579	the tissue's pertinent mechanical properties	536:579	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	1	5	theme	gel-like	160:167	arg1	solution					175:182	a gel-like water solution	158:182	a gel-like water solution of proteoglycans embedding bundles of collagen fibers	158:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	4	6	theme	mechanical	698:707	arg1	behavior					709:716	meniscal mechanical behavior	689:716	meniscal mechanical behavior in shear	689:725	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	10	7	theme	ECM	1449:1451	arg1	behavior					1464:1471	tissue ECM mechanical behavior	1442:1471	tissue ECM mechanical behavior	1442:1471	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	2	8	theme	meniscal	317:324	arg1	mechanics					326:334	meniscal mechanics	317:334	meniscal mechanics	317:334	Collagen fibers significantly contribute to meniscal mechanics, however little is known about their mechanical properties.					
34999488	1	9	theme	proteoglycans	187:199	arg1	bundles					211:217	proteoglycans embedding bundles	187:217	proteoglycans embedding bundles of collagen fibers	187:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	1	10	theme	bundles	211:217	arg1	solution					175:182	a gel-like water solution	158:182	a gel-like water solution of proteoglycans embedding bundles of collagen fibers	158:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	2	11	dep	mechanics	326:334	arg1	known					355:359	known	355:359	is known about their mechanical properties	352:393	Collagen fibers significantly contribute to meniscal mechanics, however little is known about their mechanical properties.					
34999488	9	12	used	used	1306:1309	arg2	plane					1290:1294	the shear plane	1280:1294	the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis	1280:1404	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	7	13	theme	shear	1044:1048	arg1	plane					1050:1054	the shear plane	1040:1054	the shear plane	1040:1054	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	6	14	theme	Frequency	843:851	arg1	tests					859:863	Frequency sweep tests	843:863	Frequency sweep tests	843:863	Frequency sweep tests were conducted on eight porcine meniscal specimens.					
34999488	7	15	used	used	1061:1064	arg2	fibers					999:1004	collagen fibers	990:1004	collagen fibers oriented parallel with respect to the shear plane	990:1054	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	0	16	theme	inverse	66:72	arg1	approach					98:105	an inverse finite element analysis approach	63:105	an inverse finite element analysis approach	63:105	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	12	17	theme	parameters	1741:1750	arg1	Magnitudes					1712:1721	Magnitudes	1712:1721	Magnitudes of the mechanical parameters governing the ECM and fibers	1712:1779	Magnitudes of the mechanical parameters governing the ECM and fibers were negatively related to tissue water content.					
34999488	11	18	theme	finite	1560:1565	arg1	analysis					1575:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	0	19	theme	element	81:87	arg1	approach					98:105	an inverse finite element analysis approach	63:105	an inverse finite element analysis approach	63:105	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	8	20	from	response	1150:1157	arg1	contribution					1098:1109	the contribution	1094:1109	the contribution of collagen fibers from the mechanical response	1094:1157	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	7	21	theme	collagen	990:997	arg1	fibers					999:1004	collagen fibers	990:1004	collagen fibers oriented parallel with respect to the shear plane	990:1054	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	10	22	theme	generalized	1497:1507	arg1	model					1517:1521	a generalized Maxwell model	1495:1521	a generalized Maxwell model with 3 relaxation times	1495:1545	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	0	23	theme	Mechanical	0:9	arg1	properties					11:20	Mechanical properties	0:20	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.	0:106	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	9	24	theme	fibers	1363:1368	arg1	properties					1336:1345	the elastic properties	1324:1345	the elastic properties of the collagen fibers	1324:1368	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	3	25	theme	embedded	480:487	arg1	fibers					473:478	collagen fibers	464:478	collagen fibers embedded in the ECM of the meniscus	464:514	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	9	26	theme	inverse	1374:1380	arg1	analysis					1397:1404	inverse finite element analysis	1374:1404	inverse finite element analysis	1374:1404	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	1	27	theme	extracellular	112:124	arg1	ECM					134:136	ECM	134:136	ECM	134:136	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	1	27	theme	extracellular	112:124	arg1	matrix					126:131	The extracellular matrix	108:131	The extracellular matrix (ECM) of the meniscus	108:153	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	10	28	with	model	1517:1521	arg1	times					1541:1545	3 relaxation times	1528:1545	3 relaxation times	1528:1545	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	3	29	theme	collagen	464:471	arg1	fibers					473:478	collagen fibers	464:478	collagen fibers embedded in the ECM of the meniscus	464:514	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	0	30	theme	circumferential	34:48	arg1	fibers					50:55	meniscal circumferential fibers	25:55	meniscal circumferential fibers	25:55	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	9	31	with	cohort	1223:1228	arg1	fibers					1235:1240	fibers	1235:1240	fibers	1235:1240	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	8	32	theme	fibers	1123:1128	arg1	contribution					1098:1109	the contribution	1094:1109	the contribution of collagen fibers from the mechanical response	1094:1157	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	6	33	theme	porcine	889:895	arg1	specimens					906:914	eight porcine meniscal specimens	883:914	eight porcine meniscal specimens	883:914	Frequency sweep tests were conducted on eight porcine meniscal specimens.					
34999488	3	34	theme	study	418:422	arg1	objective					400:408	The objective	396:408	The objective of this study	396:422	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	9	35	theme	element	1389:1395	arg1	analysis					1397:1404	inverse finite element analysis	1374:1404	inverse finite element analysis	1374:1404	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	11	36	theme	elastic	1640:1646	arg1	fibers					1608:1613	collagen fibers	1599:1613	collagen fibers	1599:1613	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	11	36	theme	elastic	1640:1646	arg1	elements					1648:1655	linear elastic elements	1633:1655	linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa	1633:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	4	37	theme	linear	609:614	arg1	suitable					668:675	suitable	668:675	suitable	668:675	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	4	37	theme	linear	609:614	arg1	model					659:663	a linear fiber reinforced viscoelastic constitutive model	607:663	a linear fiber reinforced viscoelastic constitutive model	607:663	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	11	38	theme	average	1667:1673	arg1	modulus					1683:1689	an average elastic modulus	1664:1689	an average elastic modulus of 287.5 ± 62.6 MPa	1664:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	7	39	theme	experimental	935:946	arg1	data					948:951	experimental data	935:951	experimental data	935:951	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	1	40	theme	fibers	231:236	arg1	bundles					211:217	proteoglycans embedding bundles	187:217	proteoglycans embedding bundles of collagen fibers	187:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	4	41	theme	reinforced	622:631	arg1	suitable					668:675	suitable	668:675	suitable	668:675	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	4	41	theme	reinforced	622:631	arg1	model					659:663	a linear fiber reinforced viscoelastic constitutive model	607:663	a linear fiber reinforced viscoelastic constitutive model	607:663	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	11	42	theme	287.5 ± 62.6 MPa	1694:1709	arg1	modulus					1683:1689	an average elastic modulus	1664:1689	an average elastic modulus of 287.5 ± 62.6 MPa	1664:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	2	43	theme	mechanical	373:382	arg1	properties					384:393	their mechanical properties	367:393	their mechanical properties	367:393	Collagen fibers significantly contribute to meniscal mechanics, however little is known about their mechanical properties.					
34999488	8	44	theme	mechanical	1180:1189	arg1	properties					1191:1200	the mechanical properties	1176:1200	the mechanical properties of the ECM	1176:1211	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	3	45	from	ECM	496:498	arg1	embedded					480:487	embedded	480:487	embedded	480:487	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	9	46	theme	second	1216:1221	arg1	cohort					1223:1228	A second cohort	1214:1228	A second cohort with fibers	1214:1240	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	4	47	from	behavior	709:716	arg1	shear					721:725	shear	721:725	shear	721:725	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	10	48	theme	testing	1411:1417	arg1	protocol					1419:1426	Our testing protocol	1407:1426	Our testing protocol	1407:1426	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	8	49	theme	ECM	1209:1211	arg1	properties					1191:1200	the mechanical properties	1176:1200	the mechanical properties of the ECM	1176:1211	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	10	50	theme	mechanical	1453:1462	arg1	behavior					1464:1471	tissue ECM mechanical behavior	1442:1471	tissue ECM mechanical behavior	1442:1471	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	1	51	theme	water	169:173	arg1	solution					175:182	a gel-like water solution	158:182	a gel-like water solution of proteoglycans embedding bundles of collagen fibers	158:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	11	52	contain	having	1657:1662	arg1	fibers					1608:1613	collagen fibers	1599:1613	collagen fibers	1599:1613	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	11	52	contain	having	1657:1662	arg2	modulus					1683:1689	an average elastic modulus	1664:1689	an average elastic modulus of 287.5 ± 62.6 MPa	1664:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	11	52	contain	having	1657:1662	arg1	elements					1648:1655	linear elastic elements	1633:1655	linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa	1633:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	12	53	theme	tissue	1808:1813	arg1	content					1821:1827	tissue water content	1808:1827	tissue water content	1808:1827	Magnitudes of the mechanical parameters governing the ECM and fibers were negatively related to tissue water content.					
34999488	4	54	theme	meniscal	689:696	arg1	behavior					709:716	meniscal mechanical behavior	689:716	meniscal mechanical behavior in shear	689:725	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	11	55	theme	collagen	1599:1606	arg1	fibers					1608:1613	collagen fibers	1599:1613	collagen fibers	1599:1613	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	11	55	theme	collagen	1599:1606	arg1	elements					1648:1655	linear elastic elements	1633:1655	linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa	1633:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	10	56	theme	tissue	1442:1447	arg1	behavior					1464:1471	tissue ECM mechanical behavior	1442:1471	tissue ECM mechanical behavior	1442:1471	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	3	57	theme	mechanical	559:568	arg1	properties					570:579	the tissue's pertinent mechanical properties	536:579	the tissue's pertinent mechanical properties	536:579	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	4	58	theme	constitutive	646:657	arg1	suitable					668:675	suitable	668:675	suitable	668:675	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	4	58	theme	constitutive	646:657	arg1	model					659:663	a linear fiber reinforced viscoelastic constitutive model	607:663	a linear fiber reinforced viscoelastic constitutive model	607:663	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	3	59	theme	meniscus	507:514	arg1	ECM					496:498	the ECM	492:498	the ECM of the meniscus	492:514	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	1	60	theme	embedding	201:209	arg1	bundles					211:217	proteoglycans embedding bundles	187:217	proteoglycans embedding bundles of collagen fibers	187:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	9	61	theme	shear	1284:1288	arg1	plane					1290:1294	the shear plane	1280:1294	the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis	1280:1404	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	2	62	theme	Collagen	273:280	arg1	fibers					282:287	Collagen fibers	273:287	Collagen fibers	273:287	Collagen fibers significantly contribute to meniscal mechanics, however little is known about their mechanical properties.					
34999488	1	63	dep	oriented	245:252	arg1	solution					175:182	a gel-like water solution	158:182	a gel-like water solution of proteoglycans embedding bundles of collagen fibers	158:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	0	64	theme	finite	74:79	arg1	approach					98:105	an inverse finite element analysis approach	63:105	an inverse finite element analysis approach	63:105	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	11	65	theme	inverse	1552:1558	arg1	analysis					1575:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis	1548:1582	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	0	66	theme	analysis	89:96	arg1	approach					98:105	an inverse finite element analysis approach	63:105	an inverse finite element analysis approach	63:105	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	1	67	theme	meniscus	146:153	arg1	ECM					134:136	ECM	134:136	ECM	134:136	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	1	67	theme	meniscus	146:153	arg1	matrix					126:131	The extracellular matrix	108:131	The extracellular matrix (ECM) of the meniscus	108:153	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	12	68	theme	mechanical	1730:1739	arg1	parameters					1741:1750	the mechanical parameters	1726:1750	the mechanical parameters governing the ECM and fibers	1726:1779	Magnitudes of the mechanical parameters governing the ECM and fibers were negatively related to tissue water content.					
34999488	9	69	theme	elastic	1328:1334	arg1	properties					1336:1345	the elastic properties	1324:1345	the elastic properties of the collagen fibers	1324:1368	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	5	70	theme	mechanical	765:774	arg1	properties					776:785	the mechanical properties	761:785	the mechanical properties governing the model	761:805	It was further hypothesized that the mechanical properties governing the model depend on the tissue's composition.					
34999488	10	71	theme	Maxwell	1509:1515	arg1	model					1517:1521	a generalized Maxwell model	1495:1521	a generalized Maxwell model with 3 relaxation times	1495:1545	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	9	72	theme	collagen	1354:1361	arg1	fibers					1363:1368	the collagen fibers	1350:1368	the collagen fibers	1350:1368	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	3	73	theme	constitutive	441:452	arg1	model					454:458	a constitutive model	439:458	a constitutive model for collagen fibers embedded in the ECM of the meniscus	439:514	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	0	74	theme	meniscal	25:32	arg1	fibers					50:55	meniscal circumferential fibers	25:55	meniscal circumferential fibers	25:55	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	8	75	theme	collagen	1114:1121	arg1	fibers					1123:1128	collagen fibers	1114:1128	collagen fibers	1114:1128	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	7	76	theme	tissue	967:972	arg1	specimens					974:982	tissue specimens	967:982	tissue specimens	967:982	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	10	77	theme	relaxation	1530:1539	arg1	times					1541:1545	3 relaxation times	1528:1545	3 relaxation times	1528:1545	Our testing protocol revealed that tissue ECM mechanical behavior could be described by a generalized Maxwell model with 3 relaxation times.					
34999488	0	78	theme	fibers	50:55	arg1	properties					11:20	Mechanical properties	0:20	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.	0:106	Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach.					
34999488	9	79	theme	finite	1382:1387	arg1	analysis					1397:1404	inverse finite element analysis	1374:1404	inverse finite element analysis	1374:1404	A second cohort with fibers orthogonally oriented with respect to the shear plane that were used to determine the elastic properties of the collagen fibers via inverse finite element analysis.					
34999488	6	80	theme	meniscal	897:904	arg1	specimens					906:914	eight porcine meniscal specimens	883:914	eight porcine meniscal specimens	883:914	Frequency sweep tests were conducted on eight porcine meniscal specimens.					
34999488	11	81	theme	linear	1633:1638	arg1	fibers					1608:1613	collagen fibers	1599:1613	collagen fibers	1599:1613	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	11	81	theme	linear	1633:1638	arg1	elements					1648:1655	linear elastic elements	1633:1655	linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa	1633:1709	The inverse finite element analysis suggested that collagen fibers can be modeled as linear elastic elements having an average elastic modulus of 287.5 ± 62.6 MPa.					
34999488	8	82	theme	mechanical	1139:1148	arg1	response					1150:1157	the mechanical response	1135:1157	the mechanical response	1135:1157	This was done to eliminate the contribution of collagen fibers from the mechanical response and characterize the mechanical properties of the ECM.					
34999488	3	83	from	embedded	480:487	arg1	ECM					496:498	the ECM	492:498	the ECM of the meniscus	492:514	The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties.					
34999488	7	84	theme	data	948:951	arg1	cohort					925:930	A first cohort	917:930	A first cohort of experimental data	917:951	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
34999488	4	85	theme	fiber	616:620	arg1	suitable					668:675	suitable	668:675	suitable	668:675	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	4	85	theme	fiber	616:620	arg1	model					659:663	a linear fiber reinforced viscoelastic constitutive model	607:663	a linear fiber reinforced viscoelastic constitutive model	607:663	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	1	86	theme	collagen	222:229	arg1	fibers					231:236	collagen fibers	222:236	collagen fibers	222:236	The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented circumferentially.					
34999488	4	87	theme	viscoelastic	633:644	arg1	suitable					668:675	suitable	668:675	suitable	668:675	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	4	87	theme	viscoelastic	633:644	arg1	model					659:663	a linear fiber reinforced viscoelastic constitutive model	607:663	a linear fiber reinforced viscoelastic constitutive model	607:663	It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear.					
34999488	7	88	theme	first	919:923	arg1	cohort					925:930	A first cohort	917:930	A first cohort of experimental data	917:951	A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel with respect to the shear plane were used.					
35980368	3	0	theme	APDMH	506:510	arg1	PAC					520:522	PAC	520:522	PAC	520:522	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	3	0	theme	APDMH	506:510	arg1	-g-ONC					512:517	antibacterial poly(APDMH)-g-ONC	487:517	antibacterial poly(APDMH)-g-ONC (PAC)	487:523	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	9	1	theme	efficient	1631:1639	arg1	applications					1662:1673	highly efficient oil/water separation applications	1624:1673	highly efficient oil/water separation applications	1624:1673	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	5	2	theme	oil/water	758:766	arg1	performances					779:790	oil/water separation performances	758:790	oil/water separation performances	758:790	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	6	3	theme	superior	928:935	arg1	elasticity					937:946	superior elasticity	928:946	superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain)	928:1023	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	6	4	from	strain	1017:1022	arg1	cycles					1003:1008	five compression-release cycles	978:1008	five compression-release cycles at 50% strain	978:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	6	5	theme	%	1015:1015	arg1	strain					1017:1022	50% strain	1013:1022	50% strain	1013:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	9	6	theme	diverse	1678:1684	arg1	conditions					1692:1701	diverse harsh conditions	1678:1701	diverse harsh conditions	1678:1701	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	8	7	theme	inoculated	1486:1495	arg1	bacteria					1497:1504	all inoculated bacteria	1482:1504	all inoculated bacteria	1482:1504	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	6	8	theme	50	1013:1014	arg1	%					1015:1015	%	1015:1015	%	1015:1015	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	2	9	theme	large-scale	342:352	arg1	application					354:364	their large-scale application	336:364	their large-scale application	336:364	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	9	10	theme	biofilm	1569:1575	arg1	formation					1577:1585	biofilm formation	1569:1585	biofilm formation	1569:1585	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	1	11	used	used	180:183	arg2	aerogels					154:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels have been widely used for various applications.					
35980368	2	12	theme	contamination	303:315	arg1	disadvantages					224:236	the disadvantages	220:236	the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria	220:327	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	6	13	dep	elasticity	937:946	arg1	recovery					963:970	96.76% height recovery	949:970	96.76% height recovery after five compression-release cycles at 50% strain	949:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	4	14	theme	network	688:694	arg1	structures					696:705	multiple network structures	679:705	multiple network structures	679:705	PAC and poly(ethyleneimine) (PEI) were chemically cross-linked using 3-glycidoxypropyltrimethox (GPTMS), aiming at constructing a PAC-g-PEI aerogel with multiple network structures.					
35980368	7	15	theme	separation	1136:1145	arg1	performances					1147:1158	excellent oil/water separation performances	1116:1158	excellent oil/water separation performances	1116:1158	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	8	16	theme	rechargeable	1333:1344	arg1	properties					1360:1369	highly efficient and rechargeable antibacterial properties	1312:1369	highly efficient and rechargeable antibacterial properties	1312:1369	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	2	17	theme	easy	298:301	arg1	contamination					303:315	easy contamination	298:315	easy contamination by bacteria	298:327	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	1	18	theme	various	189:195	arg1	applications					197:208	various applications	189:208	various applications	189:208	Nanofibrillated cellulose (NFC)-based aerogels have been widely used for various applications.					
35980368	5	19	theme	different	798:806	arg1	conditions					808:817	different conditions	798:817	different conditions	798:817	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	5	20	theme	separation	768:777	arg1	performances					779:790	oil/water separation performances	758:790	oil/water separation performances	758:790	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	8	21	theme	antibacterial	1346:1358	arg1	properties					1360:1369	highly efficient and rechargeable antibacterial properties	1312:1369	highly efficient and rechargeable antibacterial properties	1312:1369	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	8	22	theme	chlorinated	1270:1280	arg1	aerogel					1282:1288	the chlorinated aerogel	1266:1288	the chlorinated aerogel of PAC-g-PEI-Cl	1266:1304	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	3	23	theme	-5,5-dimethyl	410:422	arg1	APDMH					435:439	APDMH	435:439	APDMH	435:439	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	3	23	theme	-5,5-dimethyl	410:422	arg1	hydantoin					424:432	3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin	381:432	3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH)	381:440	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	6	24	theme	compression	911:921	arg1	cycles					901:906	>50 cycles	897:906	>50 cycles of compression	897:921	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	5	25	theme	composite	736:744	arg1	aerogel					746:752	composite aerogel	736:752	composite aerogel	736:752	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	1	26	theme	Nanofibrillated	116:130	arg1	aerogels					154:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels have been widely used for various applications.					
35980368	4	27	with	aerogel	666:672	arg1	structures					696:705	multiple network structures	679:705	multiple network structures	679:705	PAC and poly(ethyleneimine) (PEI) were chemically cross-linked using 3-glycidoxypropyltrimethox (GPTMS), aiming at constructing a PAC-g-PEI aerogel with multiple network structures.					
35980368	8	28	theme	PAC-g-PEI-Cl	1293:1304	arg1	aerogel					1282:1288	the chlorinated aerogel	1266:1288	the chlorinated aerogel of PAC-g-PEI-Cl	1266:1304	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	7	29	theme	oil/water	1126:1134	arg1	performances					1147:1158	excellent oil/water separation performances	1116:1158	excellent oil/water separation performances	1116:1158	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	7	30	theme	excellent	1116:1124	arg1	performances					1147:1158	excellent oil/water separation performances	1116:1158	excellent oil/water separation performances	1116:1158	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	7	31	theme	satisfactory	1173:1184	arg1	efficiency					1197:1206	a satisfactory separation efficiency	1171:1206	a satisfactory separation efficiency of over 99%	1171:1218	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	6	32	theme	compression-release	983:1001	arg1	cycles					1003:1008	five compression-release cycles	978:1008	five compression-release cycles at 50% strain	978:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	9	33	theme	harsh	1686:1690	arg1	conditions					1692:1701	diverse harsh conditions	1678:1701	diverse harsh conditions	1678:1701	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	9	34	theme	oil/water	1641:1649	arg1	applications					1662:1673	highly efficient oil/water separation applications	1624:1673	highly efficient oil/water separation applications	1624:1673	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	7	35	theme	%	1218:1218	arg1	efficiency					1197:1206	a satisfactory separation efficiency	1171:1206	a satisfactory separation efficiency of over 99%	1171:1218	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	7	35	theme	%	1218:1218	arg1	flux					1224:1227	flux	1224:1227	flux of over 9500 L·m-2·h-1	1224:1250	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	9	36	theme	separation	1651:1660	arg1	applications					1662:1673	highly efficient oil/water separation applications	1624:1673	highly efficient oil/water separation applications	1624:1673	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	0	37	theme	Nanofibrillated	49:63	arg1	Aerogels					81:88	Nanofibrillated Cellulose-Based Aerogels	49:88	Nanofibrillated Cellulose-Based Aerogels	49:88	Mechanically Tough and Regenerable Antibacterial Nanofibrillated Cellulose-Based Aerogels for Oil/Water Separation.					
35980368	4	38	theme	multiple	679:686	arg1	structures					696:705	multiple network structures	679:705	multiple network structures	679:705	PAC and poly(ethyleneimine) (PEI) were chemically cross-linked using 3-glycidoxypropyltrimethox (GPTMS), aiming at constructing a PAC-g-PEI aerogel with multiple network structures.					
35980368	8	39	dep	Escherichia	1396:1406	arg1	coli					1408:1411	coli	1408:1411	coli	1408:1411	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	7	40	with	aerogel	1103:1109	arg1	performances					1147:1158	excellent oil/water separation performances	1116:1158	excellent oil/water separation performances	1116:1158	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	3	41	theme	oxidized	457:464	arg1	ONC					471:473	ONC	471:473	ONC	471:473	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	3	41	theme	oxidized	457:464	arg1	NFC					466:468	oxidized NFC	457:468	oxidized NFC (ONC)	457:474	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	6	42	dep	resistance	885:894	arg1	cycles					901:906	>50 cycles	897:906	>50 cycles of compression	897:921	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	5	43	theme	performances	779:790	arg1	behaviors					723:731	The mechanical behaviors	708:731	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions	708:817	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	9	44	theme	PAC-g-PEI-Cl	1536:1547	arg1	aerogel					1549:1555	PAC-g-PEI-Cl aerogel	1536:1555	PAC-g-PEI-Cl aerogel	1536:1555	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	2	45	theme	stability	257:265	arg1	disadvantages					224:236	the disadvantages	220:236	the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria	220:327	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	8	46	theme	efficient	1319:1327	arg1	properties					1360:1369	highly efficient and rechargeable antibacterial properties	1312:1369	highly efficient and rechargeable antibacterial properties	1312:1369	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	7	47	theme	separation	1186:1195	arg1	efficiency					1197:1206	a satisfactory separation efficiency	1171:1206	a satisfactory separation efficiency of over 99%	1171:1218	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	6	48	theme	height	956:961	arg1	recovery					963:970	96.76% height recovery	949:970	96.76% height recovery after five compression-release cycles at 50% strain	949:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	7	49	theme	underwater-oleophobic	1060:1080	arg1	properties					1082:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	6	50	theme	fatigue	877:883	arg1	resistance					885:894	outstanding fatigue resistance	865:894	outstanding fatigue resistance (>50 cycles of compression)	865:922	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	2	51	theme	structural	246:255	arg1	stability					257:265	poor structural stability	241:265	poor structural stability	241:265	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	7	52	theme	obtained	1030:1037	arg1	properties					1082:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	3	53	theme	poly	501:504	arg1	PAC					520:522	PAC	520:522	PAC	520:522	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	3	53	theme	poly	501:504	arg1	-g-ONC					512:517	antibacterial poly(APDMH)-g-ONC	487:517	antibacterial poly(APDMH)-g-ONC (PAC)	487:523	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	0	54	theme	Cellulose-Based	65:79	arg1	Aerogels					81:88	Nanofibrillated Cellulose-Based Aerogels	49:88	Nanofibrillated Cellulose-Based Aerogels	49:88	Mechanically Tough and Regenerable Antibacterial Nanofibrillated Cellulose-Based Aerogels for Oil/Water Separation.					
35980368	6	55	theme	%	954:954	arg1	recovery					963:970	96.76% height recovery	949:970	96.76% height recovery after five compression-release cycles at 50% strain	949:1022	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	6	56	theme	outstanding	865:875	arg1	resistance					885:894	outstanding fatigue resistance	865:894	outstanding fatigue resistance (>50 cycles of compression)	865:922	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	2	57	theme	poor	241:244	arg1	stability					257:265	poor structural stability	241:265	poor structural stability	241:265	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	7	58	theme	L·m-2·h-1	1242:1250	arg1	efficiency					1197:1206	a satisfactory separation efficiency	1171:1206	a satisfactory separation efficiency of over 99%	1171:1218	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	7	58	theme	L·m-2·h-1	1242:1250	arg1	flux					1224:1227	flux	1224:1227	flux of over 9500 L·m-2·h-1	1224:1250	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	1	59	theme	-based	147:152	arg1	aerogels					154:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels	116:161	Nanofibrillated cellulose (NFC)-based aerogels have been widely used for various applications.					
35980368	6	60	theme	96.76	949:953	arg1	%					954:954	%	954:954	%	954:954	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	7	61	theme	superhydrophilic	1039:1054	arg1	properties					1082:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties	1026:1091	The obtained superhydrophilic and underwater-oleophobic properties endow the aerogel with excellent oil/water separation performances, achieving a satisfactory separation efficiency of over 99% and flux of over 9500 L·m-2·h-1.					
35980368	2	62	theme	toughness	283:291	arg1	disadvantages					224:236	the disadvantages	220:236	the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria	220:327	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	3	63	theme	antibacterial	487:499	arg1	PAC					520:522	PAC	520:522	PAC	520:522	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	3	63	theme	antibacterial	487:499	arg1	-g-ONC					512:517	antibacterial poly(APDMH)-g-ONC	487:517	antibacterial poly(APDMH)-g-ONC (PAC)	487:523	In this work, 3-(3'-acrylicacidpropylester)-5,5-dimethyl hydantoin (APDMH) was grafted on oxidized NFC (ONC) to prepare antibacterial poly(APDMH)-g-ONC (PAC).					
35980368	8	64	theme	Escherichia	1396:1406	arg1	6.72-log					1387:1394	6.72-log	1387:1394	6.72-log Escherichia coli	1387:1411	Furthermore, the chlorinated aerogel of PAC-g-PEI-Cl shows highly efficient and rechargeable antibacterial properties, can inactivate 6.72-log Escherichia coli and 6.60-log Staphylococcus aureus within 10 min, and can still kill all inoculated bacteria after 50 cycles.					
35980368	0	65	theme	Oil/Water	94:102	arg1	Separation					104:113	Oil/Water Separation	94:113	Oil/Water Separation	94:113	Mechanically Tough and Regenerable Antibacterial Nanofibrillated Cellulose-Based Aerogels for Oil/Water Separation.					
35980368	6	66	theme	PAC-g-PEI	838:846	arg1	aerogel					848:854	PAC-g-PEI aerogel	838:854	PAC-g-PEI aerogel	838:854	PAC-g-PEI aerogel exhibits outstanding fatigue resistance (>50 cycles of compression) and superior elasticity (96.76% height recovery after five compression-release cycles at 50% strain).					
35980368	2	67	theme	mechanical	272:281	arg1	toughness					283:291	low mechanical toughness	268:291	low mechanical toughness	268:291	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	4	68	theme	PAC-g-PEI	656:664	arg1	aerogel					666:672	a PAC-g-PEI aerogel	654:672	a PAC-g-PEI aerogel with multiple network structures	654:705	PAC and poly(ethyleneimine) (PEI) were chemically cross-linked using 3-glycidoxypropyltrimethox (GPTMS), aiming at constructing a PAC-g-PEI aerogel with multiple network structures.					
35980368	9	69	theme	promising	1600:1608	arg1	candidate					1610:1618	a promising candidate	1598:1618	a promising candidate for highly efficient oil/water separation applications	1598:1673	In addition, PAC-g-PEI-Cl aerogel can inhibit biofilm formation, making it a promising candidate for highly efficient oil/water separation applications in diverse harsh conditions.					
35980368	5	70	theme	aerogel	746:752	arg1	behaviors					723:731	The mechanical behaviors	708:731	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions	708:817	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35980368	2	71	theme	low	268:270	arg1	toughness					283:291	low mechanical toughness	268:291	low mechanical toughness	268:291	However, the disadvantages of poor structural stability, low mechanical toughness, and easy contamination by bacteria hinder their large-scale application.					
35980368	5	72	theme	mechanical	712:721	arg1	behaviors					723:731	The mechanical behaviors	708:731	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions	708:817	The mechanical behaviors of composite aerogel and oil/water separation performances under different conditions were investigated.					
35410335	2	0	theme	co-occurrence	367:379	arg1	networks					381:388	co-occurrence networks	367:388	co-occurrence networks	367:388	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	1	1	theme	biofloc-based	273:285	arg1	systems					295:301	biofloc-based culture systems	273:301	biofloc-based culture systems	273:301	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	8	2	theme	bacterial	1657:1665	arg1	assembly					1667:1674	the bacterial assembly	1653:1674	the bacterial assembly of the shrimp culture system	1653:1703	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	5	3	dep	%	813:813	arg1	50					811:812	50	811:812	50	811:812	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	2	4	from	interaction	354:364	arg1	systems					465:471	biofloc-based culture systems	443:471	biofloc-based culture systems	443:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	1	5	theme	reliable	180:187	arg1	conditions					218:227	more reliable and environmentally friendly conditions	175:227	more reliable and environmentally friendly conditions for shrimp growth	175:245	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	4	6	theme	habitats	706:713	arg1	compositions					678:689	compositions	678:689	compositions	678:689	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	4	6	theme	habitats	706:713	arg1	structures					663:672	bacterial community structures	643:672	bacterial community structures	643:672	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	2	7	theme	sucrose	330:336	arg1	addition					338:345	sucrose addition	330:345	sucrose addition	330:345	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	1	8	theme	environmentally	193:207	arg1	conditions					218:227	more reliable and environmentally friendly conditions	175:227	more reliable and environmentally friendly conditions for shrimp growth	175:245	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	3	9	theme	sucrose	551:557	arg1	addition					559:566	sucrose addition	551:566	sucrose addition	551:566	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	1	10	theme	shrimp	233:238	arg1	growth					240:245	shrimp growth	233:245	shrimp growth	233:245	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	7	11	theme	shrimp	1394:1399	arg1	growth					1401:1406	shrimp growth	1394:1406	shrimp growth	1394:1406	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	1	12	from	bacteria	261:268	arg1	systems					295:301	biofloc-based culture systems	273:301	biofloc-based culture systems	273:301	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	1	13	theme	carbon	148:153	arg1	source					155:160	an effective carbon source	135:160	an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems	135:301	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	1	13	theme	carbon	148:153	arg1	Sucrose					124:130	Sucrose	124:130	Sucrose	124:130	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	1	14	theme	effective	138:146	arg1	source					155:160	an effective carbon source	135:160	an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems	135:301	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	1	14	theme	effective	138:146	arg1	Sucrose					124:130	Sucrose	124:130	Sucrose	124:130	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	9	15	theme	beneficial	1771:1780	arg1	taxa					1782:1785	certain beneficial taxa	1763:1785	certain beneficial taxa	1763:1785	These results provide a basis for selectively regulating certain beneficial taxa to improve shrimp growth in culture systems.					
35410335	7	16	theme	keystone	1366:1373	arg1	taxa					1375:1378	keystone taxa	1366:1378	keystone taxa for improving shrimp growth	1366:1406	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	7	16	theme	keystone	1366:1373	arg1	some					1342:1345	some	1342:1345	some	1342:1345	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	5	17	dep	communities	957:967	arg1	%					945:945	%	945:945	%	945:945	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	8	18	from	water	1484:1488	arg1	assembly					1470:1477	gut bacterial community assembly	1446:1477	gut bacterial community assembly from water and biofloc	1446:1500	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	5	19	theme	addition	911:918	arg1	groups					920:925	the sucrose addition groups	899:925	the sucrose addition groups	899:925	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	5	20	dep	%	945:945	arg1	33					943:944	33	943:944	33	943:944	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	3	21	from	communities	581:591	arg1	bioflocs					619:626	bioflocs	619:626	bioflocs	619:626	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	21	from	communities	581:591	arg1	gut					633:635	gut	633:635	gut	633:635	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	21	from	communities	581:591	arg1	water					612:616	water	612:616	water	612:616	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	21	from	communities	581:591	arg1	habitats					602:609	three habitats	596:609	three habitats (water, bioflocs, and gut)	596:636	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	9	22	theme	shrimp	1798:1803	arg1	growth					1805:1810	shrimp growth	1798:1810	shrimp growth in culture systems	1798:1829	These results provide a basis for selectively regulating certain beneficial taxa to improve shrimp growth in culture systems.					
35410335	0	23	theme	shrimp	101:106	arg1	system					116:121	the shrimp culture system	97:121	the shrimp culture system	97:121	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	2	24	theme	bacterial	418:426	arg1	communities					428:438	bacterial communities	418:438	bacterial communities	418:438	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	0	25	theme	system	116:121	arg1	convergence					60:70	bacterial community convergence	40:70	bacterial community convergence	40:70	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	0	25	theme	system	116:121	arg1	stability					84:92	network stability	76:92	network stability	76:92	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	0	26	theme	Sucrose	0:6	arg1	addition					8:15	Sucrose addition	0:15	Sucrose addition	0:15	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	5	27	theme	bacterial	947:955	arg1	communities					957:967	only about 33% bacterial communities	932:967	only about 33% bacterial communities	932:967	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	8	28	theme	%	1568:1568	arg1	ratios					1553:1558	the ratios	1549:1558	the ratios of 55-91% and 67-83%, respectively	1549:1593	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	2	29	theme	culture	457:463	arg1	systems					465:471	biofloc-based culture systems	443:471	biofloc-based culture systems	443:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	3	30	dep	habitats	602:609	arg1	bioflocs					619:626	bioflocs	619:626	bioflocs	619:626	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	30	dep	habitats	602:609	arg1	gut					633:635	gut	633:635	gut	633:635	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	30	dep	habitats	602:609	arg1	water					612:616	water	612:616	water	612:616	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	3	30	dep	habitats	602:609	arg1	habitats					602:609	three habitats	596:609	three habitats (water, bioflocs, and gut)	596:636	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	6	31	theme	Sucrose	1043:1049	arg1	addition					1051:1058	Sucrose addition	1043:1058	Sucrose addition	1043:1058	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	0	32	theme	bacterial	40:48	arg1	convergence					60:70	bacterial community convergence	40:70	bacterial community convergence	40:70	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	5	33	theme	control	1019:1025	arg1	system					1035:1040	the control culture system	1015:1040	the control culture system	1015:1040	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	2	34	from	mechanisms	404:413	arg1	systems					465:471	biofloc-based culture systems	443:471	biofloc-based culture systems	443:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	7	35	theme	culture	1322:1328	arg1	systems					1330:1336	the sucrose addition culture systems	1301:1336	the sucrose addition culture systems	1301:1336	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	0	36	theme	network	76:82	arg1	stability					84:92	network stability	76:92	network stability	76:92	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	5	37	theme	gut	815:817	arg1	communities					829:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	7	38	theme	sucrose	1305:1311	arg1	systems					1330:1336	the sucrose addition culture systems	1301:1336	the sucrose addition culture systems	1301:1336	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	8	39	theme	gut	1446:1448	arg1	assembly					1470:1477	gut bacterial community assembly	1446:1477	gut bacterial community assembly from water and biofloc	1446:1500	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	2	40	theme	communities	428:438	arg1	interaction					354:364	interaction	354:364	interaction	354:364	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	40	theme	communities	428:438	arg1	networks					381:388	co-occurrence networks	367:388	co-occurrence networks	367:388	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	40	theme	communities	428:438	arg1	mechanisms					404:413	assembly mechanisms	395:413	assembly mechanisms	395:413	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	8	41	theme	community	1460:1468	arg1	assembly					1470:1477	gut bacterial community assembly	1446:1477	gut bacterial community assembly from water and biofloc	1446:1500	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	3	42	theme	addition	559:566	arg1	effects					540:546	the effects	536:546	the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut)	536:636	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	4	43	from	groups	738:743	arg1	similar					727:733	similar	727:733	similar	727:733	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	6	44	theme	phylum	1108:1113	arg1	Actinobacteria					1115:1128	the phylum Actinobacteria	1104:1128	the phylum Actinobacteria	1104:1128	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	8	45	theme	culture	1690:1696	arg1	system					1698:1703	the shrimp culture system	1679:1703	the shrimp culture system	1679:1703	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	4	46	with	groups	738:743	arg1	addition					758:765	sucrose addition	750:765	sucrose addition	750:765	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	4	47	dep	structures	663:672	arg1	The					639:641	The	639:641	The	639:641	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	1	48	theme	culture	287:293	arg1	systems					295:301	biofloc-based culture systems	273:301	biofloc-based culture systems	273:301	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	5	49	dep	communities	829:839	arg1	%					813:813	%	813:813	%	813:813	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	3	50	theme	bacterial	571:579	arg1	communities					581:591	bacterial communities	571:591	bacterial communities in three habitats (water, bioflocs, and gut)	571:636	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	5	51	theme	biofloc	876:882	arg1	communities					884:894	water and biofloc communities	866:894	communities	884:894	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	2	52	from	networks	381:388	arg1	systems					465:471	biofloc-based culture systems	443:471	biofloc-based culture systems	443:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	53	theme	addition	338:345	arg1	influence					317:325	the influence	313:325	the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems	313:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	3	54	from	effects	540:546	arg1	communities					581:591	bacterial communities	571:591	bacterial communities in three habitats (water, bioflocs, and gut)	571:636	Here, we comprehensively investigated the effects of sucrose addition on bacterial communities in three habitats (water, bioflocs, and gut).					
35410335	1	55	theme	friendly	209:216	arg1	conditions					218:227	more reliable and environmentally friendly conditions	175:227	more reliable and environmentally friendly conditions for shrimp growth	175:245	Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.					
35410335	4	56	theme	community	653:661	arg1	structures					663:672	bacterial community structures	643:672	bacterial community structures	643:672	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	5	57	theme	water	866:870	arg1	communities					884:894	water and biofloc communities	866:894	communities	884:894	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	9	58	theme	certain	1763:1769	arg1	taxa					1782:1785	certain beneficial taxa	1763:1785	certain beneficial taxa	1763:1785	These results provide a basis for selectively regulating certain beneficial taxa to improve shrimp growth in culture systems.					
35410335	4	59	theme	sucrose	750:756	arg1	addition					758:765	sucrose addition	750:765	sucrose addition	750:765	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	5	60	theme	sucrose	903:909	arg1	groups					920:925	the sucrose addition groups	899:925	the sucrose addition groups	899:925	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	6	61	theme	gut	1209:1211	arg1	habitats					1213:1220	gut habitats	1209:1220	gut habitats	1209:1220	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	7	62	theme	core	1229:1232	arg1	taxa					1234:1237	These core taxa	1223:1237	These core taxa	1223:1237	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	5	63	from	communities	884:894	arg1	groups					920:925	the sucrose addition groups	899:925	the sucrose addition groups	899:925	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	2	64	from	influence	317:325	arg1	interaction					354:364	interaction	354:364	interaction	354:364	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	64	from	influence	317:325	arg1	networks					381:388	co-occurrence networks	367:388	co-occurrence networks	367:388	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	64	from	influence	317:325	arg1	mechanisms					404:413	assembly mechanisms	395:413	assembly mechanisms	395:413	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	0	65	theme	culture	108:114	arg1	system					116:121	the shrimp culture system	97:121	the shrimp culture system	97:121	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	9	66	theme	culture	1815:1821	arg1	systems					1823:1829	culture systems	1815:1829	culture systems	1815:1829	These results provide a basis for selectively regulating certain beneficial taxa to improve shrimp growth in culture systems.					
35410335	8	67	with	select	1537:1542	arg1	ratios					1553:1558	the ratios	1549:1558	the ratios of 55-91% and 67-83%, respectively	1549:1593	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	5	68	theme	bacterial	819:827	arg1	communities					829:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	6	69	theme	core	1081:1084	arg1	taxa					1086:1089	core taxa	1081:1089	core taxa belonging to the phylum Actinobacteria	1081:1128	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	2	70	theme	assembly	395:402	arg1	mechanisms					404:413	assembly mechanisms	395:413	assembly mechanisms	395:413	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	8	71	theme	%	1579:1579	arg1	ratios					1553:1558	the ratios	1549:1558	the ratios of 55-91% and 67-83%, respectively	1549:1593	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	2	72	dep	interaction	354:364	arg1	the					350:352	the	350:352	the	350:352	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	2	73	theme	biofloc-based	443:455	arg1	systems					465:471	biofloc-based culture systems	443:471	biofloc-based culture systems	443:471	However, the influence of sucrose addition on the interaction, co-occurrence networks, and assembly mechanisms of bacterial communities in biofloc-based culture systems remains largely unknown.					
35410335	0	74	theme	community	50:58	arg1	convergence					60:70	bacterial community convergence	40:70	bacterial community convergence	40:70	Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system.					
35410335	7	75	theme	addition	1313:1320	arg1	systems					1330:1336	the sucrose addition culture systems	1301:1336	the sucrose addition culture systems	1301:1336	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	8	76	from	biofloc	1494:1500	arg1	assembly					1470:1477	gut bacterial community assembly	1446:1477	gut bacterial community assembly from water and biofloc	1446:1500	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	9	77	from	growth	1805:1810	arg1	systems					1823:1829	culture systems	1815:1829	culture systems	1815:1829	These results provide a basis for selectively regulating certain beneficial taxa to improve shrimp growth in culture systems.					
35410335	5	78	theme	culture	1027:1033	arg1	system					1035:1040	the control culture system	1015:1040	the control culture system	1015:1040	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	8	79	theme	sucrose	1428:1434	arg1	addition					1436:1443	sucrose addition	1428:1443	sucrose addition	1428:1443	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	6	80	dep	families	1138:1145	arg1	families					1138:1145	the families	1134:1145	the families Rhodobacteraceae and Flavobacteriaceae	1134:1184	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	6	80	dep	families	1138:1145	arg1	Flavobacteriaceae					1168:1184	Flavobacteriaceae	1168:1184	Flavobacteriaceae	1168:1184	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	6	80	dep	families	1138:1145	arg1	Rhodobacteraceae					1147:1162	Rhodobacteraceae	1147:1162	Rhodobacteraceae	1147:1162	Sucrose addition accordantly enriched core taxa belonging to the phylum Actinobacteria and the families Rhodobacteraceae and Flavobacteriaceae in water, biofloc, and gut habitats.					
35410335	5	81	attach	derived	853:859	arg1	communities					884:894	water and biofloc communities	866:894	communities	884:894	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	5	81	attach	derived	853:859	arg2	communities					829:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities	801:839	More than 50% gut bacterial communities were mainly derived from water and biofloc communities in the sucrose addition groups, but only about 33% bacterial communities migrated from water and biofloc to the gut in the control culture system.					
35410335	8	82	theme	sucrose	1612:1618	arg1	addition					1620:1627	sucrose addition	1612:1627	sucrose addition	1612:1627	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	7	83	theme	network	1280:1286	arg1	stability					1288:1296	bacterial network stability	1270:1296	bacterial network stability	1270:1296	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	8	84	theme	shrimp	1683:1688	arg1	system					1698:1703	the shrimp culture system	1679:1703	the shrimp culture system	1679:1703	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	4	85	from	similar	727:733	arg1	groups					738:743	groups	738:743	groups with sucrose addition	738:765	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	7	86	theme	bacterial	1270:1278	arg1	stability					1288:1296	bacterial network stability	1270:1296	bacterial network stability	1270:1296	These core taxa were important for maintaining bacterial network stability in the sucrose addition culture systems and some were identified as keystone taxa for improving shrimp growth.					
35410335	4	87	theme	bacterial	643:651	arg1	structures					663:672	bacterial community structures	643:672	bacterial community structures	643:672	The bacterial community structures and compositions of these three habitats became more similar in groups with sucrose addition, compared with those in controls.					
35410335	8	88	theme	bacterial	1450:1458	arg1	assembly					1470:1477	gut bacterial community assembly	1446:1477	gut bacterial community assembly from water and biofloc	1446:1500	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
35410335	8	89	theme	system	1698:1703	arg1	assembly					1667:1674	the bacterial assembly	1653:1674	the bacterial assembly of the shrimp culture system	1653:1703	Furthermore, after sucrose addition, gut bacterial community assembly from water and biofloc was dominated by the heterogeneous select with the ratios of 55-91% and 67-83%, respectively, indicating that sucrose addition can directionally shape the bacterial assembly of the shrimp culture system.					
36444025	0	0	theme	refrigerated	84:95	arg1	carp					97:100	refrigerated carp	84:100	refrigerated carp	84:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	0	1	from	pattern	15:21	arg1	stabilization					67:79	texture stabilization	59:79	texture stabilization of refrigerated carp	59:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	5	2	theme	proteomic	659:667	arg1	analysis					669:676	label-free proteomic analysis	648:676	label-free proteomic analysis	648:676	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	2	3	theme	enzyme	356:361	arg1	activities					363:372	lower endogenous enzyme activities	339:372	lower endogenous enzyme activities	339:372	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	6	4	theme	coated	1003:1008	arg1	fillets					1010:1016	coated fillets	1003:1016	coated fillets	1003:1016	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	6	5	theme	protein	921:927	arg1	turnover					929:936	protein turnover	921:936	protein turnover	921:936	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	1	6	theme	protective	159:168	arg1	pattern					170:176	the protective pattern	155:176	the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets	155:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	1	7	theme	refrigerated	258:269	arg1	fillets					282:288	refrigerated grass carp fillets	258:288	refrigerated grass carp fillets	258:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	5	8	theme	coated	731:736	arg1	fillets					738:744	coated fillets	731:744	coated fillets than that of the control	731:769	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	7	9	theme	myofibrillar	1113:1124	arg1	degradation					1134:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	1	10	theme	grass	271:275	arg1	carp					277:280	grass carp	271:280	refrigerated grass carp fillets	258:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	0	11	theme	carp	97:100	arg1	stabilization					67:79	texture stabilization	59:79	texture stabilization of refrigerated carp	59:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	6	12	theme	protein	893:899	arg1	phosphorylation					901:915	protein phosphorylation	893:915	protein phosphorylation	893:915	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	7	13	theme	protein	1126:1132	arg1	degradation					1134:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	1	14	theme	carp	277:280	arg1	fillets					282:288	refrigerated grass carp fillets	258:288	refrigerated grass carp fillets	258:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	6	15	from	up-regulation	986:998	arg1	fillets					1010:1016	coated fillets	1003:1016	coated fillets	1003:1016	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	7	16	theme	phosphorylation	1158:1172	arg1	level					1174:1178	protein phosphorylation level	1150:1178	protein phosphorylation level	1150:1178	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	7	17	theme	enzyme-induced	1098:1111	arg1	degradation					1134:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	7	18	theme	texture	1205:1211	arg1	properties					1213:1222	the texture properties	1201:1222	the texture properties of refrigerated fillets	1201:1246	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	6	19	dep	showed	979:984	arg1	compared					1018:1025	compared	1018:1025	showed up-regulation in coated fillets compared to the control on day 12	979:1050	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	2	20	theme	coated	391:396	arg1	fillets					398:404	coated fillets	391:404	coated fillets	391:404	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	0	21	theme	protective	4:13	arg1	pattern					15:21	The protective pattern	0:21	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp	0:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	6	22	theme	tissue	875:880	arg1	structure					882:890	tissue structure	875:890	tissue structure	875:890	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	6	23	from	control	1034:1040	arg1	day					1045:1047	day 12	1045:1050	day 12	1045:1050	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	2	24	theme	higher	316:321	arg1	force					329:333	higher shear force	316:333	higher shear force	316:333	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	5	25	located	observed	719:726	arg2	proteome					683:690	the proteome	679:690	the proteome closer to fresh sample	679:713	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	5	25	located	observed	719:726	arg1	fillets					738:744	coated fillets	731:744	coated fillets than that of the control	731:769	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	1	26	theme	chitosan	181:188	arg1	coating					190:196	chitosan coating	181:196	chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets	181:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	5	27	theme	hierarchical	796:807	arg1	analysis					817:824	hierarchical cluster analysis	796:824	hierarchical cluster analysis	796:824	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	1	28	theme	fillets	282:288	arg1	stabilization					241:253	texture stabilization	233:253	texture stabilization of refrigerated grass carp fillets	233:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	5	29	theme	label-free	648:657	arg1	analysis					669:676	label-free proteomic analysis	648:676	label-free proteomic analysis	648:676	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	7	30	theme	endogenous	1087:1096	arg1	degradation					1134:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	endogenous enzyme-induced myofibrillar protein degradation	1087:1144	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	1	31	theme	coating	190:196	arg1	pattern					170:176	the protective pattern	155:176	the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets	155:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	5	32	theme	cluster	809:815	arg1	analysis					817:824	hierarchical cluster analysis	796:824	hierarchical cluster analysis	796:824	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	6	33	theme	most	969:972	arg1	DAPs					974:977	most DAPs	969:977	most DAPs	969:977	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	4	34	theme	protein	557:563	arg1	changes					577:583	protein composition changes	557:583	protein composition changes	557:583	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
36444025	2	35	theme	endogenous	345:354	arg1	activities					363:372	lower endogenous enzyme activities	339:372	lower endogenous enzyme activities	339:372	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	4	36	theme	composition	565:575	arg1	changes					577:583	protein composition changes	557:583	protein composition changes	557:583	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
36444025	0	37	theme	active	41:46	arg1	coating					48:54	chitosan-based active coating	26:54	chitosan-based active coating	26:54	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	1	38	theme	green	212:216	arg1	extract					222:228	green tea extract	212:228	green tea extract	212:228	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	0	39	theme	chitosan-based	26:39	arg1	coating					48:54	chitosan-based active coating	26:54	chitosan-based active coating	26:54	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	0	40	theme	proteolysis	134:144	arg1	perspective					119:129	the perspective	115:129	the perspective of proteolysis	115:144	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	4	41	theme	products	625:632	arg1	accumulation					589:600	accumulation	589:600	accumulation of protein degradation products	589:632	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
36444025	4	41	theme	products	625:632	arg1	changes					577:583	protein composition changes	557:583	protein composition changes	557:583	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
36444025	1	42	theme	tea	218:220	arg1	extract					222:228	green tea extract	212:228	green tea extract	212:228	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	7	43	theme	protein	1150:1156	arg1	level					1174:1178	protein phosphorylation level	1150:1178	protein phosphorylation level	1150:1178	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	7	44	theme	refrigerated	1227:1238	arg1	fillets					1240:1246	refrigerated fillets	1227:1246	refrigerated fillets	1227:1246	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	6	45	theme	differential	841:852	arg1	proteins					854:861	33 differential proteins	838:861	33 differential proteins involved in tissue structure	838:890	Meanwhile, 33 differential proteins involved in tissue structure, protein phosphorylation and protein turnover were further screened out, and most DAPs showed up-regulation in coated fillets compared to the control on day 12.					
36444025	2	46	theme	lower	339:343	arg1	activities					363:372	lower endogenous enzyme activities	339:372	lower endogenous enzyme activities	339:372	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	0	47	theme	coating	48:54	arg1	pattern					15:21	The protective pattern	0:21	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp	0:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	5	48	theme	closer	692:697	arg1	proteome					683:690	the proteome	679:690	the proteome closer to fresh sample	679:713	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	7	49	theme	fillets	1240:1246	arg1	properties					1213:1222	the texture properties	1201:1222	the texture properties of refrigerated fillets	1201:1246	Presumably, the coating modulated endogenous enzyme-induced myofibrillar protein degradation and protein phosphorylation level, thereby stabilizing the texture properties of refrigerated fillets.					
36444025	4	50	theme	protein	605:611	arg1	products					625:632	protein degradation products	605:632	protein degradation products	605:632	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
36444025	5	51	theme	fresh	702:706	arg1	sample					708:713	fresh sample	702:713	fresh sample	702:713	According to label-free proteomic analysis, the proteome closer to fresh sample was observed in coated fillets than that of the control, as supported by PCA and hierarchical cluster analysis.					
36444025	2	52	located	observed	379:386	arg1	general					307:313	general	307:313	general	307:313	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	2	52	located	observed	379:386	arg2	activities					363:372	lower endogenous enzyme activities	339:372	lower endogenous enzyme activities	339:372	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	2	52	located	observed	379:386	arg1	fillets					398:404	coated fillets	391:404	coated fillets	391:404	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	2	52	located	observed	379:386	arg2	force					329:333	higher shear force	316:333	higher shear force	316:333	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	2	53	theme	shear	323:327	arg1	force					329:333	higher shear force	316:333	higher shear force	316:333	In general, higher shear force and lower endogenous enzyme activities were observed in coated fillets, with the max.					
36444025	3	54	theme	calpain	445:451	arg1	level					421:425	level	421:425	level of cathepsins and calpain	421:451	level of cathepsins and calpain decreasing by 30.2 ∼ 39.6 % when compared to the control during storage.					
36444025	3	55	theme	cathepsins	430:439	arg1	level					421:425	level	421:425	level of cathepsins and calpain	421:451	level of cathepsins and calpain decreasing by 30.2 ∼ 39.6 % when compared to the control during storage.					
36444025	1	56	theme	texture	233:239	arg1	stabilization					241:253	texture stabilization	233:253	texture stabilization of refrigerated grass carp fillets	233:288	Herein, the protective pattern of chitosan coating enriched with green tea extract on texture stabilization of refrigerated grass carp fillets was explored.					
36444025	0	57	theme	texture	59:65	arg1	stabilization					67:79	texture stabilization	59:79	texture stabilization of refrigerated carp	59:100	The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis.					
36444025	4	58	theme	degradation	613:623	arg1	products					625:632	protein degradation products	605:632	protein degradation products	605:632	Meanwhile, the coating reduced protein composition changes and accumulation of protein degradation products.					
35716790	1	0	theme	casting	255:261	arg1	method					263:268	solution casting method	246:268	solution casting method	246:268	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	2	1	theme	PLA/CA	275:280	arg1	membrane					282:289	The PLA/CA membrane	271:289	The PLA/CA membrane	271:289	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	9	2	theme	chicken	1316:1322	arg1	meat					1331:1334	chicken breast meat	1316:1334	chicken breast meat	1316:1334	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	3	3	theme	high	579:582	arg1	transparency					584:595	high transparency	579:595	high transparency	579:595	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	4	theme	good	558:561	arg1	flexibility					563:573	good flexibility	558:573	good flexibility	558:573	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	9	5	theme	chicken	1278:1284	arg1	meat					1293:1296	chicken breast meat	1278:1296	chicken breast meat	1278:1296	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	8	6	theme	environmental	1052:1064	arg1	pH					1066:1067	the environmental pH	1048:1067	the environmental pH (ammonia and acetic acid vapor)	1048:1099	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	6	7	theme	same	836:839	arg1	time					841:844	the same time	832:844	the same time	832:844	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	7	8	theme	barrier	1023:1029	arg1	properties					1031:1040	excellent UV barrier properties	1010:1040	excellent UV barrier properties	1010:1040	PLA/AL films exhibit excellent UV barrier properties.					
35716790	1	9	dep	alizarin	216:223	arg1	AL					226:227	AL	226:227	AL	226:227	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	3	10	theme	same	421:424	arg1	time					426:429	the same time	417:429	the same time	417:429	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	6	11	theme	PLA/CS	871:876	arg1	membrane					878:885	PLA/CS membrane	871:885	PLA/CS membrane	871:885	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	4	12	theme	FE-SEM	613:618	arg1	results					602:608	The results	598:608	The results of FE-SEM and FTIR	598:627	The results of FE-SEM and FTIR showed that CS and AL were uniformly dispersed in PLA matrix and had good compatibility with PLA.					
35716790	9	13	theme	composite	1393:1401	arg1	membrane					1403:1410	functional PLA/CA composite membrane	1375:1410	functional PLA/CA composite membrane	1375:1410	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	8	14	theme	color	1159:1163	arg1	change					1165:1170	reversible color change	1148:1170	reversible color change of yellow	1148:1180	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	5	15	theme	PLA/CS	757:762	arg1	activities					743:752	The antioxidant activities	727:752	The antioxidant activities of PLA/CS and PLA/AL composite films	727:789	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	5	15	theme	PLA/CS	757:762	arg1	%					801:801	43.3 %	796:801	43.3 %	796:801	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	9	16	theme	breast	1286:1291	arg1	meat					1293:1296	chicken breast meat	1278:1296	chicken breast meat	1278:1296	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	9	17	theme	breast	1324:1329	arg1	meat					1331:1334	chicken breast meat	1316:1334	chicken breast meat	1316:1334	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	0	18	theme	food	88:91	arg1	packaging					93:101	food packaging	88:101	food packaging	88:101	Poly (lactic acid)-based pH responsive membrane combined with chitosan and alizarin for food packaging.					
35716790	4	19	theme	good	698:701	arg1	compatibility					703:715	good compatibility	698:715	good compatibility	698:715	The results of FE-SEM and FTIR showed that CS and AL were uniformly dispersed in PLA matrix and had good compatibility with PLA.					
35716790	2	20	theme	part	335:338	arg1	zone					318:321	the antibacterial zone	300:321	the antibacterial zone of the edge part (PLA/CS)	300:347	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	20	theme	part	335:338	arg1	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	8	21	theme	yellow	1175:1180	arg1	change					1165:1170	reversible color change	1148:1170	reversible color change of yellow	1148:1180	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	3	22	contain	have	553:556	arg1	membrane					544:551	the prepared PLA/CA composite membrane	514:551	the prepared PLA/CA composite membrane	514:551	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	22	contain	have	553:556	arg2	transparency					584:595	high transparency	579:595	high transparency	579:595	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	22	contain	have	553:556	arg2	flexibility					563:573	good flexibility	558:573	good flexibility	558:573	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	6	23	theme	membrane	878:885	arg1	high					946:949	high	946:949	high	946:949	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	6	23	theme	membrane	878:885	arg1	rates					862:866	the inhibitory rates	847:866	the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus	847:936	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	7	24	theme	UV	1020:1021	arg1	properties					1031:1040	excellent UV barrier properties	1010:1040	excellent UV barrier properties	1010:1040	PLA/AL films exhibit excellent UV barrier properties.					
35716790	7	25	theme	excellent	1010:1018	arg1	properties					1031:1040	excellent UV barrier properties	1010:1040	excellent UV barrier properties	1010:1040	PLA/AL films exhibit excellent UV barrier properties.					
35716790	3	26	theme	prepared	518:525	arg1	membrane					544:551	the prepared PLA/CA composite membrane	514:551	the prepared PLA/CA composite membrane	514:551	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	2	27	contain	contains	291:298	arg2	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	27	contain	contains	291:298	arg1	membrane					282:289	The PLA/CA membrane	271:289	The PLA/CA membrane	271:289	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	27	contain	contains	291:298	arg2	zone					318:321	the antibacterial zone	300:321	the antibacterial zone of the edge part (PLA/CS)	300:347	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	6	28	from	time	841:844	arg1	high					946:949	high	946:949	high	946:949	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	6	28	from	time	841:844	arg1	rates					862:866	the inhibitory rates	847:866	the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus	847:936	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	3	29	theme	environmentally	436:450	arg1	citrate					482:488	the environmentally friendly plasticizer tributyl citrate	432:488	the environmentally friendly plasticizer tributyl citrate (TBC)	432:494	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	29	theme	environmentally	436:450	arg1	TBC					491:493	TBC	491:493	TBC	491:493	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	2	30	theme	antibacterial	304:316	arg1	zone					318:321	the antibacterial zone	300:321	the antibacterial zone of the edge part (PLA/CS)	300:347	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	3	31	theme	friendly	452:459	arg1	citrate					482:488	the environmentally friendly plasticizer tributyl citrate	432:488	the environmentally friendly plasticizer tributyl citrate (TBC)	432:494	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	31	theme	friendly	452:459	arg1	TBC					491:493	TBC	491:493	TBC	491:493	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	8	32	theme	acetic	1082:1087	arg1	vapor					1094:1098	acetic acid vapor	1082:1098	acetic acid vapor	1082:1098	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	1	33	theme	-based	131:136	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	8	34	theme	alkaline	1222:1229	arg1	condition					1231:1239	alkaline condition	1222:1239	alkaline condition	1222:1239	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	4	35	theme	FTIR	624:627	arg1	results					602:608	The results	598:608	The results of FE-SEM and FTIR	598:627	The results of FE-SEM and FTIR showed that CS and AL were uniformly dispersed in PLA matrix and had good compatibility with PLA.					
35716790	4	36	theme	PLA	679:681	arg1	matrix					683:688	PLA matrix	679:688	PLA matrix	679:688	The results of FE-SEM and FTIR showed that CS and AL were uniformly dispersed in PLA matrix and had good compatibility with PLA.					
35716790	1	37	theme	functional	138:147	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	0	38	theme	lactic	6:11	arg1	Poly					0:3	Poly	0:3	Poly (lactic acid)	0:17	Poly (lactic acid)-based pH responsive membrane combined with chitosan and alizarin for food packaging.					
35716790	0	38	theme	lactic	6:11	arg1	acid					13:16	lactic acid	6:16	lactic acid	6:16	Poly (lactic acid)-based pH responsive membrane combined with chitosan and alizarin for food packaging.					
35716790	9	39	theme	color	1359:1363	arg1	change					1365:1370	the color change	1355:1370	the color change of functional PLA/CA composite membrane	1355:1410	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	8	40	dep	pH	1066:1067	arg1	ammonia					1070:1076	ammonia	1070:1076	ammonia	1070:1076	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	8	40	dep	pH	1066:1067	arg1	vapor					1094:1098	acetic acid vapor	1082:1098	acetic acid vapor	1082:1098	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	1	41	theme	partition	149:157	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	42	theme	composite	159:167	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	43	contain	containing	187:196	arg2	CS					208:209	CS	208:209	CS	208:209	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	43	contain	containing	187:196	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	43	contain	containing	187:196	arg2	alizarin					216:223	alizarin	216:223	alizarin (AL)	216:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	43	contain	containing	187:196	arg2	chitosan					198:205	chitosan	198:205	chitosan (CS)	198:210	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	5	44	theme	antioxidant	731:741	arg1	activities					743:752	The antioxidant activities	727:752	The antioxidant activities of PLA/CS and PLA/AL composite films	727:789	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	5	44	theme	antioxidant	731:741	arg1	%					801:801	43.3 %	796:801	43.3 %	796:801	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	2	45	theme	edge	330:333	arg1	PLA/CS					341:346	PLA/CS	341:346	PLA/CS	341:346	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	45	theme	edge	330:333	arg1	part					335:338	the edge part	326:338	the edge part (PLA/CS)	326:347	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	46	theme	detection	369:377	arg1	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	8	47	theme	PLA/AL	1125:1130	arg1	membrane					1132:1139	the PLA/AL membrane	1121:1139	the PLA/AL membrane	1121:1139	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	1	48	theme	membrane	169:176	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	0	49	theme	responsive	28:37	arg1	membrane					39:46	pH responsive membrane	25:46	pH responsive membrane combined with chitosan and alizarin for food packaging	25:101	Poly (lactic acid)-based pH responsive membrane combined with chitosan and alizarin for food packaging.					
35716790	8	50	theme	acidic	1188:1193	arg1	condition					1195:1203	acidic condition	1188:1203	acidic condition	1188:1203	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	2	51	theme	central	391:397	arg1	PLA/AL					405:410	PLA/AL	405:410	PLA/AL	405:410	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	51	theme	central	391:397	arg1	part					399:402	the central part	387:402	the central part (PLA/AL)	387:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	3	52	theme	plasticizer	461:471	arg1	citrate					482:488	the environmentally friendly plasticizer tributyl citrate	432:488	the environmentally friendly plasticizer tributyl citrate (TBC)	432:494	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	52	theme	plasticizer	461:471	arg1	TBC					491:493	TBC	491:493	TBC	491:493	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	5	53	theme	PLA/AL	768:773	arg1	films					785:789	PLA/AL composite films	768:789	PLA/AL composite films	768:789	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	2	54	theme	pH	357:358	arg1	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	3	55	theme	tributyl	473:480	arg1	citrate					482:488	the environmentally friendly plasticizer tributyl citrate	432:488	the environmentally friendly plasticizer tributyl citrate (TBC)	432:494	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	3	55	theme	tributyl	473:480	arg1	TBC					491:493	TBC	491:493	TBC	491:493	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	9	56	theme	meat	1293:1296	arg1	storage					1267:1273	storage	1267:1273	storage	1267:1273	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	9	56	theme	meat	1293:1296	arg1	packaging					1253:1261	packaging	1253:1261	packaging	1253:1261	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	5	57	theme	composite	775:783	arg1	films					785:789	PLA/AL composite films	768:789	PLA/AL composite films	768:789	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	9	58	dep	packaging	1253:1261	arg1	the					1249:1251	the	1249:1251	the	1249:1251	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	5	59	theme	films	785:789	arg1	activities					743:752	The antioxidant activities	727:752	The antioxidant activities of PLA/CS and PLA/AL composite films	727:789	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	5	59	theme	films	785:789	arg1	%					801:801	43.3 %	796:801	43.3 %	796:801	The antioxidant activities of PLA/CS and PLA/AL composite films were 43.3 % and 72.8 %, respectively.					
35716790	9	60	theme	PLA/CA	1386:1391	arg1	membrane					1403:1410	functional PLA/CA composite membrane	1375:1410	functional PLA/CA composite membrane	1375:1410	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	3	61	theme	PLA/CA	527:532	arg1	membrane					544:551	the prepared PLA/CA composite membrane	514:551	the prepared PLA/CA composite membrane	514:551	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	1	62	theme	poly	106:109	arg1	PLA/CA					179:184	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA)	104:185	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	8	63	theme	reversible	1148:1157	arg1	change					1165:1170	reversible color change	1148:1170	reversible color change of yellow	1148:1180	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	6	64	theme	inhibitory	851:860	arg1	high					946:949	high	946:949	high	946:949	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	6	64	theme	inhibitory	851:860	arg1	rates					862:866	the inhibitory rates	847:866	the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus	847:936	At the same time, the inhibitory rates of PLA/CS membrane against Escherichia coli and Staphylococcus aureus were as high as 87.91 % and 75.17 %, respectively.					
35716790	2	65	theme	part	399:402	arg1	zone					318:321	the antibacterial zone	300:321	the antibacterial zone of the edge part (PLA/CS)	300:347	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	2	65	theme	part	399:402	arg1	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	3	66	theme	composite	534:542	arg1	membrane					544:551	the prepared PLA/CA composite membrane	514:551	the prepared PLA/CA composite membrane	514:551	At the same time, the environmentally friendly plasticizer tributyl citrate (TBC) was added to make the prepared PLA/CA composite membrane have good flexibility and high transparency.					
35716790	8	67	theme	acid	1089:1092	arg1	vapor					1094:1098	acetic acid vapor	1082:1098	acetic acid vapor	1082:1098	When the environmental pH (ammonia and acetic acid vapor) changed repeatedly, the PLA/AL membrane showed reversible color change of yellow under acidic condition and purple under alkaline condition.					
35716790	9	68	theme	meat	1331:1334	arg1	freshness					1303:1311	the freshness	1299:1311	the freshness of chicken breast meat	1299:1334	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	9	69	theme	functional	1375:1384	arg1	membrane					1403:1410	functional PLA/CA composite membrane	1375:1410	functional PLA/CA composite membrane	1375:1410	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	9	70	theme	membrane	1403:1410	arg1	change					1365:1370	the color change	1355:1370	the color change of functional PLA/CA composite membrane	1355:1410	During the packaging and storage of chicken breast meat, the freshness of chicken breast meat can be detected by the color change of functional PLA/CA composite membrane.					
35716790	2	71	theme	response	360:367	arg1	zone					379:382	the pH response detection zone	353:382	the pH response detection zone of the central part (PLA/AL)	353:411	The PLA/CA membrane contains the antibacterial zone of the edge part (PLA/CS) and the pH response detection zone of the central part (PLA/AL).					
35716790	1	72	theme	solution	246:253	arg1	method					263:268	solution casting method	246:268	solution casting method	246:268	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	7	73	theme	PLA/AL	989:994	arg1	films					996:1000	PLA/AL films	989:1000	PLA/AL films	989:1000	PLA/AL films exhibit excellent UV barrier properties.					
35716790	1	74	theme	lactic	112:117	arg1	poly					106:109	A poly	104:109	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL)	104:228	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35716790	1	74	theme	lactic	112:117	arg1	acid					119:122	lactic acid	112:122	lactic acid	112:122	A poly (lactic acid) (PLA) -based functional partition composite membrane (PLA/CA) containing chitosan (CS) and alizarin (AL) was designed by solution casting method.					
35074131	3	0	theme	CUR-CS-LS	361:369	arg1	239 nm					376:381	239 nm	376:381	239 nm	376:381	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	3	0	theme	CUR-CS-LS	361:369	arg1	diameter					339:346	the average diameter	327:346	the average diameter of CS-LS and CUR-CS-LS	327:369	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	5	1	theme	hydrophobic	710:720	arg1	interactions					722:733	hydrophobic interactions	710:733	hydrophobic interactions	710:733	Curcumin is encapsulated in the hydrophobic core through hydrophobic interactions.					
35074131	6	2	theme	curcumin	801:808	arg1	stability					771:779	thermal stability	763:779	thermal stability	763:779	Encapsulation improves the thermal stability and pH stability of curcumin.					
35074131	6	2	theme	curcumin	801:808	arg1	stability					788:796	pH stability	785:796	pH stability	785:796	Encapsulation improves the thermal stability and pH stability of curcumin.					
35074131	7	3	theme	pH	971:972	arg1	conditions					974:983	the same heat treatment and pH conditions	943:983	conditions	974:983	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	4	4	theme	electrostatic	625:637	arg1	interactions					639:650	electrostatic interactions	625:650	electrostatic interactions	625:650	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	7	5	from	efficiency	854:863	arg1	CUR-CS-LS					880:888	CUR-CS-LS	880:888	CUR-CS-LS	880:888	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	4	6	theme	aromatic	435:442	arg1	rings					444:448	the aromatic rings	431:448	the aromatic rings of lignosulfonate	431:466	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	7	7	theme	heat	952:955	arg1	treatment					957:965	the same heat treatment and pH conditions	943:983	treatment	957:965	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	9	8	theme	matrix	1151:1156	arg1	swelling					1158:1165	matrix swelling	1151:1165	matrix swelling	1151:1165	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	6	9	dep	stability	771:779	arg1	the					759:761	the	759:761	the	759:761	Encapsulation improves the thermal stability and pH stability of curcumin.					
35074131	8	10	theme	aqueous	1069:1075	arg1	solution					1077:1084	aqueous solution	1069:1084	aqueous solution	1069:1084	Encapsulation also increases the antioxidant activity of curcumin in aqueous solution.					
35074131	4	11	theme	micelles	511:518	arg1	core					503:506	the hydrophobic core	487:506	the hydrophobic core of micelles	487:518	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	7	12	theme	same	947:950	arg1	treatment					957:965	the same heat treatment and pH conditions	943:983	treatment	957:965	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	5	13	theme	hydrophobic	685:695	arg1	core					697:700	the hydrophobic core	681:700	the hydrophobic core	681:700	Curcumin is encapsulated in the hydrophobic core through hydrophobic interactions.					
35074131	9	14	from	diffusion	1137:1145	arg1	addition					1090:1097	addition	1090:1097	addition	1090:1097	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	6	15	theme	pH	785:786	arg1	stability					788:796	pH stability	785:796	pH stability	785:796	Encapsulation improves the thermal stability and pH stability of curcumin.					
35074131	4	16	theme	π-π	528:530	arg1	interactions					532:543	π-π interactions	528:543	π-π interactions	528:543	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	1	17	theme	polyelectrolyte	216:230	arg1	self-assembly					232:244	polyelectrolyte self-assembly	216:244	polyelectrolyte self-assembly	216:244	In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared through polyelectrolyte self-assembly.					
35074131	10	18	theme	promising	1222:1230	arg1	system					1241:1246	an effective promising delivery system	1209:1246	an effective promising delivery system for encapsulating hydrophobic biologically active substances	1209:1307	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	10	18	theme	promising	1222:1230	arg1	CS-LS					1196:1200	CS-LS	1196:1200	CS-LS	1196:1200	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	10	19	theme	effective	1212:1220	arg1	system					1241:1246	an effective promising delivery system	1209:1246	an effective promising delivery system for encapsulating hydrophobic biologically active substances	1209:1307	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	10	19	theme	effective	1212:1220	arg1	CS-LS					1196:1200	CS-LS	1196:1200	CS-LS	1196:1200	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	6	20	theme	thermal	763:769	arg1	stability					771:779	thermal stability	763:779	thermal stability	763:779	Encapsulation improves the thermal stability and pH stability of curcumin.					
35074131	3	21	theme	average	331:337	arg1	239 nm					376:381	239 nm	376:381	239 nm	376:381	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	3	21	theme	average	331:337	arg1	diameter					339:346	the average diameter	327:346	the average diameter of CS-LS and CUR-CS-LS	327:369	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	4	22	theme	hydrophobic	491:501	arg1	core					503:506	the hydrophobic core	487:506	the hydrophobic core of micelles	487:518	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	4	23	theme	hydrophilic	599:609	arg1	shell					611:615	a hydrophilic shell	597:615	a hydrophilic shell through electrostatic interactions	597:650	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	8	24	from	activity	1045:1052	arg1	solution					1077:1084	aqueous solution	1069:1084	aqueous solution	1069:1084	Encapsulation also increases the antioxidant activity of curcumin in aqueous solution.					
35074131	0	25	theme	antioxidant	34:44	arg1	properties					46:55	antioxidant properties	34:55	antioxidant properties	34:55	Preparation, characterization and antioxidant properties of curcumin encapsulated chitosan/lignosulfonate micelles.					
35074131	10	26	theme	delivery	1232:1239	arg1	system					1241:1246	an effective promising delivery system	1209:1246	an effective promising delivery system for encapsulating hydrophobic biologically active substances	1209:1307	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	10	26	theme	delivery	1232:1239	arg1	CS-LS					1196:1200	CS-LS	1196:1200	CS-LS	1196:1200	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	0	27	theme	curcumin	60:67	arg1	characterization					13:28	characterization	13:28	characterization	13:28	Preparation, characterization and antioxidant properties of curcumin encapsulated chitosan/lignosulfonate micelles.					
35074131	0	27	theme	curcumin	60:67	arg1	properties					46:55	antioxidant properties	34:55	antioxidant properties	34:55	Preparation, characterization and antioxidant properties of curcumin encapsulated chitosan/lignosulfonate micelles.					
35074131	0	27	theme	curcumin	60:67	arg1	Preparation					0:10	Preparation	0:10	Preparation	0:10	Preparation, characterization and antioxidant properties of curcumin encapsulated chitosan/lignosulfonate micelles.					
35074131	7	28	theme	curcumin	868:875	arg1	efficiency					854:863	the retention efficiency	840:863	the retention efficiency of curcumin in CUR-CS-LS	840:888	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	3	29	theme	CS-LS	351:355	arg1	239 nm					376:381	239 nm	376:381	239 nm	376:381	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	3	29	theme	CS-LS	351:355	arg1	diameter					339:346	the average diameter	327:346	the average diameter of CS-LS and CUR-CS-LS	327:369	The results showed that the average diameter of CS-LS and CUR-CS-LS were 239 nm and 286 nm, respectively.					
35074131	1	30	theme	chitosan/lignosulfonate	130:152	arg1	micelles					164:171	chitosan/lignosulfonate composite micelles	130:171	chitosan/lignosulfonate composite micelles (CS-LS)	130:179	In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared through polyelectrolyte self-assembly.					
35074131	1	30	theme	chitosan/lignosulfonate	130:152	arg1	CS-LS					174:178	CS-LS	174:178	CS-LS	174:178	In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared through polyelectrolyte self-assembly.					
35074131	7	31	theme	retention	844:852	arg1	efficiency					854:863	the retention efficiency	840:863	the retention efficiency of curcumin in CUR-CS-LS	840:888	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	1	32	theme	composite	154:162	arg1	micelles					164:171	chitosan/lignosulfonate composite micelles	130:171	chitosan/lignosulfonate composite micelles (CS-LS)	130:179	In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared through polyelectrolyte self-assembly.					
35074131	1	32	theme	composite	154:162	arg1	CS-LS					174:178	CS-LS	174:178	CS-LS	174:178	In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared through polyelectrolyte self-assembly.					
35074131	9	33	theme	release	1104:1110	arg1	diffusion					1137:1145	diffusion	1137:1145	diffusion	1137:1145	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	9	33	theme	release	1104:1110	arg1	mechanism					1112:1120	the release mechanism	1100:1120	the release mechanism of curcumin	1100:1132	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	4	34	theme	hydrophobic	577:587	arg1	core					589:592	the hydrophobic core	573:592	the hydrophobic core	573:592	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	4	35	theme	lignosulfonate	453:466	arg1	rings					444:448	the aromatic rings	431:448	the aromatic rings of lignosulfonate	431:466	The results show that the aromatic rings of lignosulfonate are assembled into the hydrophobic core of micelles through π-π interactions, and chitosan binds outside the hydrophobic core as a hydrophilic shell through electrostatic interactions.					
35074131	10	36	theme	active	1291:1296	arg1	substances					1298:1307	hydrophobic biologically active substances	1266:1307	hydrophobic biologically active substances	1266:1307	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35074131	0	37	theme	chitosan/lignosulfonate	82:104	arg1	micelles					106:113	chitosan/lignosulfonate micelles	82:113	chitosan/lignosulfonate micelles	82:113	Preparation, characterization and antioxidant properties of curcumin encapsulated chitosan/lignosulfonate micelles.					
35074131	9	38	from	swelling	1158:1165	arg1	addition					1090:1097	addition	1090:1097	addition	1090:1097	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	8	39	theme	antioxidant	1033:1043	arg1	activity					1045:1052	the antioxidant activity	1029:1052	the antioxidant activity of curcumin in aqueous solution	1029:1084	Encapsulation also increases the antioxidant activity of curcumin in aqueous solution.					
35074131	9	40	theme	curcumin	1125:1132	arg1	diffusion					1137:1145	diffusion	1137:1145	diffusion	1137:1145	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	9	40	theme	curcumin	1125:1132	arg1	mechanism					1112:1120	the release mechanism	1100:1120	the release mechanism of curcumin	1100:1132	In addition, the release mechanism of curcumin is diffusion and matrix swelling.					
35074131	7	41	theme	free	825:828	arg1	curcumin					830:837	free curcumin	825:837	free curcumin	825:837	Compared with free curcumin, the retention efficiency of curcumin in CUR-CS-LS increased by approximately 6.66 and 6.46 times under the same heat treatment and pH conditions, respectively.					
35074131	8	42	theme	curcumin	1057:1064	arg1	activity					1045:1052	the antioxidant activity	1029:1052	the antioxidant activity of curcumin in aqueous solution	1029:1084	Encapsulation also increases the antioxidant activity of curcumin in aqueous solution.					
35074131	10	43	theme	hydrophobic	1266:1276	arg1	substances					1298:1307	hydrophobic biologically active substances	1266:1307	hydrophobic biologically active substances	1266:1307	These findings explain that CS-LS may be an effective promising delivery system for encapsulating hydrophobic biologically active substances.					
35897873	5	0	theme	bending	822:828	arg1	strength					830:837	bending strength	822:837	bending strength	822:837	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	4	1	theme	microscopy	539:548	arg1	techniques					585:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	1	2	theme	substrate	171:179	arg1	properties					151:160	the mechanical properties	136:160	the mechanical properties of paper substrate	136:179	This article describes how crystalline or fibrous nanocellulose influences the mechanical properties of paper substrate.					
35897873	6	3	from	disturbances	995:1006	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	1011:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	6	4	theme	observed	869:876	arg1	decrease					878:885	the observed decrease	865:885	the observed decrease in the strength properties of the paper after applying some NC compositions	865:961	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	6	4	theme	observed	869:876	arg1	due					966:968	due	966:968	due	966:968	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	6	5	theme	paper	921:925	arg1	properties					903:912	the strength properties	890:912	the strength properties of the paper	890:925	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	3	6	theme	paper	393:397	arg1	reinforcement					372:384	Selective reinforcement	362:384	Selective reinforcement of the paper treated with the nanocellulose samples mentioned above	362:452	Selective reinforcement of the paper treated with the nanocellulose samples mentioned above was observed.					
35897873	4	7	theme	roentgenography	551:565	arg1	techniques					585:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	5	8	theme	elongation	712:721	arg1	coefficient					723:733	elongation coefficient	712:733	elongation coefficient	712:733	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	5	9	theme	physical	649:656	arg1	properties					658:667	physical properties	649:667	physical properties	649:667	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	7	10	located	observed	1154:1161	arg1	case					1170:1173	the case	1166:1173	the case of paper reinforced with nanocellulose functionalized with carboxyl groups	1166:1248	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	7	10	located	observed	1154:1161	arg1	hand					1111:1114	the other hand	1101:1114	the other hand	1101:1114	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	7	10	located	observed	1154:1161	arg2	strength					1141:1148	significantly increased strength	1117:1148	significantly increased strength	1117:1148	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	2	11	theme	cellulose	340:348	arg1	nanofibers					350:359	carboxy cellulose nanofibers	332:359	carboxy cellulose nanofibers	332:359	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	6	12	theme	NC	947:948	arg1	compositions					950:961	some NC compositions	942:961	some NC compositions	942:961	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	5	13	theme	air	800:802	arg1	permeability					804:815	Bendtsen air permeability	791:815	Bendtsen air permeability	791:815	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	7	14	theme	paper	1178:1182	arg1	case					1170:1173	the case	1166:1173	the case of paper reinforced with nanocellulose functionalized with carboxyl groups	1166:1248	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	4	15	theme	electron	530:537	arg1	microscopy					539:548	scanning electron microscopy	521:548	scanning electron microscopy	521:548	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	7	16	theme	carboxyl	1234:1241	arg1	groups					1243:1248	carboxyl groups	1234:1248	carboxyl groups	1234:1248	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	3	17	theme	nanocellulose	416:428	arg1	samples					430:436	the nanocellulose samples	412:436	the nanocellulose samples mentioned above	412:452	Selective reinforcement of the paper treated with the nanocellulose samples mentioned above was observed.					
35897873	4	18	theme	scanning	521:528	arg1	microscopy					539:548	scanning electron microscopy	521:548	scanning electron microscopy	521:548	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	1	19	theme	crystalline	88:98	arg1	nanocellulose					111:123	crystalline or fibrous nanocellulose	88:123	crystalline or fibrous nanocellulose	88:123	This article describes how crystalline or fibrous nanocellulose influences the mechanical properties of paper substrate.					
35897873	5	20	theme	Elmendorf	736:744	arg1	resistance					751:760	Elmendorf tear resistance	736:760	Elmendorf tear resistance	736:760	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	6	21	from	bonds	1020:1024	arg1	loss					977:980	the loss	973:980	the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	973:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	5	22	theme	tensile	697:703	arg1	index					705:709	tensile index	697:709	tensile index	697:709	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	5	23	theme	nanocellulose	624:636	arg1	coating					638:644	nanocellulose coating	624:644	nanocellulose coating	624:644	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	2	24	theme	carboxy	332:338	arg1	nanofibers					350:359	carboxy cellulose nanofibers	332:359	carboxy cellulose nanofibers	332:359	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	0	25	theme	Structure	27:35	arg1	Influence					0:8	Influence	0:8	Influence of Nanocellulose Structure on Paper Reinforcement.	0:59	Influence of Nanocellulose Structure on Paper Reinforcement.					
35897873	6	26	theme	hydrogen	1011:1018	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	1011:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	5	27	theme	coating	638:644	arg1	effect					614:619	the effect	610:619	the effect of nanocellulose coating on physical properties	610:667	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	1	28	theme	fibrous	103:109	arg1	nanocellulose					111:123	crystalline or fibrous nanocellulose	88:123	crystalline or fibrous nanocellulose	88:123	This article describes how crystalline or fibrous nanocellulose influences the mechanical properties of paper substrate.					
35897873	0	29	theme	Nanocellulose	13:25	arg1	Structure					27:35	Nanocellulose Structure	13:35	Nanocellulose Structure	13:35	Influence of Nanocellulose Structure on Paper Reinforcement.					
35897873	6	30	theme	strength	894:901	arg1	properties					903:912	the strength properties	890:912	the strength properties of the paper	890:925	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	5	31	theme	Bendtsen	763:770	arg1	roughness					780:788	Bendtsen surface roughness	763:788	Bendtsen surface roughness	763:788	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	4	32	theme	fibre	486:490	arg1	structure					492:500	the fibre structure	482:500	the fibre structure	482:500	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	7	33	theme	increased	1131:1139	arg1	strength					1141:1148	significantly increased strength	1117:1148	significantly increased strength	1117:1148	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	0	34	theme	Paper	40:44	arg1	Reinforcement					46:58	Paper Reinforcement	40:58	Paper Reinforcement	40:58	Influence of Nanocellulose Structure on Paper Reinforcement.					
35897873	6	35	theme	disturbances	995:1006	arg1	loss					977:980	the loss	973:980	the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	973:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	5	36	theme	surface	772:778	arg1	roughness					780:788	Bendtsen surface roughness	763:788	Bendtsen surface roughness	763:788	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	6	37	from	decrease	878:885	arg1	properties					903:912	the strength properties	890:912	the strength properties of the paper	890:925	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	4	38	theme	spectroscopy	572:583	arg1	techniques					585:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	scanning electron microscopy, roentgenography, and spectroscopy techniques	521:594	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	7	39	theme	other	1105:1109	arg1	hand					1111:1114	the other hand	1101:1114	the other hand	1101:1114	On the other hand, significantly increased strength was observed in the case of paper reinforced with nanocellulose functionalized with carboxyl groups.					
35897873	6	40	theme	paper	1081:1085	arg1	substrate					1087:1095	the paper substrate	1077:1095	the paper substrate	1077:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	6	41	theme	potential	985:993	arg1	disturbances					995:1006	potential disturbances	985:1006	potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	985:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	6	42	from	loss	977:980	arg1	bonds					1020:1024	hydrogen bonds	1011:1024	hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate	1011:1095	It can be concluded that the observed decrease in the strength properties of the paper after applying some NC compositions is due to the loss of potential disturbances in hydrogen bonds between the nanocellulose dispersed in ethanol and the paper substrate.					
35897873	0	43	from	Influence	0:8	arg1	Reinforcement					46:58	Paper Reinforcement	40:58	Paper Reinforcement	40:58	Influence of Nanocellulose Structure on Paper Reinforcement.					
35897873	4	44	from	change	472:477	arg1	structure					492:500	the fibre structure	482:500	the fibre structure	482:500	The change in the fibre structure was assessed using scanning electron microscopy, roentgenography, and spectroscopy techniques.					
35897873	2	45	theme	available	220:228	arg1	nanocrystals					240:251	commercially available cellulose nanocrystals	207:251	commercially available cellulose nanocrystals	207:251	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	2	46	theme	cellulose	230:238	arg1	nanocrystals					240:251	commercially available cellulose nanocrystals	207:251	commercially available cellulose nanocrystals	207:251	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	5	47	theme	tear	746:749	arg1	resistance					751:760	Elmendorf tear resistance	736:760	Elmendorf tear resistance	736:760	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	1	48	theme	mechanical	140:149	arg1	properties					151:160	the mechanical properties	136:160	the mechanical properties of paper substrate	136:179	This article describes how crystalline or fibrous nanocellulose influences the mechanical properties of paper substrate.					
35897873	5	49	from	effect	614:619	arg1	properties					658:667	physical properties	649:667	physical properties	649:667	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35897873	3	50	theme	Selective	362:370	arg1	reinforcement					372:384	Selective reinforcement	362:384	Selective reinforcement of the paper treated with the nanocellulose samples mentioned above	362:452	Selective reinforcement of the paper treated with the nanocellulose samples mentioned above was observed.					
35897873	2	51	theme	cellulose	276:284	arg1	nanofibers					286:295	mechanically prepared cellulose nanofibers	254:295	mechanically prepared cellulose nanofibers dispersed in water or ethanol	254:325	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	2	52	used	used	202:205	arg2	we					199:200	we	199:200	we	199:200	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	2	53	theme	prepared	267:274	arg1	nanofibers					286:295	mechanically prepared cellulose nanofibers	254:295	mechanically prepared cellulose nanofibers dispersed in water or ethanol	254:325	In this context, we used commercially available cellulose nanocrystals, mechanically prepared cellulose nanofibers dispersed in water or ethanol, and carboxy cellulose nanofibers.					
35897873	1	54	theme	paper	165:169	arg1	substrate					171:179	paper substrate	165:179	paper substrate	165:179	This article describes how crystalline or fibrous nanocellulose influences the mechanical properties of paper substrate.					
35897873	5	55	theme	Bendtsen	791:798	arg1	permeability					804:815	Bendtsen air permeability	791:815	Bendtsen air permeability	791:815	In addition, the effect of nanocellulose coating on physical properties was evaluated, specifically tensile index, elongation coefficient, Elmendorf tear resistance, Bendtsen surface roughness, Bendtsen air permeability, and bending strength.					
35259349	3	0	theme	vector	303:308	arg1	storage					310:316	long-term vector storage	293:316	long-term vector storage	293:316	While this allows for long-term vector storage without loss of activity, it is inconvenient and involves high costs and logistical challenges.					
35259349	7	1	theme	buffer	1153:1158	arg1	combination					1122:1132	a combination	1120:1132	a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx	1120:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	7	2	theme	different	1050:1058	arg1	concentration					1065:1077	different salt concentration	1050:1077	different salt concentration	1050:1077	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	9	3	theme	processes	1413:1421	arg1	optimizations					1382:1394	future optimizations	1375:1394	future optimizations of freeze-drying processes	1375:1421	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	6	4	theme	secondary	870:878	arg1	drying					880:885	secondary drying	870:885	secondary drying	870:885	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	6	5	theme	residual	958:965	arg1	moisture					967:974	the residual moisture	954:974	the residual moisture	954:974	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	8	6	from	25 °C	1337:1341	arg1	2-8 °C					1302:1307	2-8 °C	1302:1307	2-8 °C	1302:1307	1.5% provided stable long-term storage at 2-8 °C and for at least 4 weeks at 25 °C.					
35259349	0	7	from	Studies	11:17	arg1	Stabilization					22:34	Stabilization	22:34	Stabilization of AAV Vector Formulations by Lyophilization	22:79	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization.					
35259349	7	8	theme	salt	1060:1063	arg1	concentration					1065:1077	different salt concentration	1050:1077	different salt concentration	1050:1077	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	6	9	theme	AAV8	786:789	arg1	vectors					791:797	AAV8 vectors	786:797	AAV8 vectors	786:797	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	7	10	theme	10 mM	1137:1141	arg1	buffer					1153:1158	10 mM phosphate buffer	1137:1158	10 mM phosphate buffer	1137:1158	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	4	11	theme	freeze-dried	471:482	arg1	formulations					484:495	freeze-dried formulations	471:495	freeze-dried formulations	471:495	Therefore, there is a need for AAV formulations, such as freeze-dried formulations, that allow for long-term storage at 2-8 °C.					
35259349	9	12	theme	AAV	1427:1429	arg1	products					1457:1464	AAV vector-based gene therapy products	1427:1464	AAV vector-based gene therapy products	1427:1464	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	7	13	theme	phosphate	1143:1151	arg1	buffer					1153:1158	10 mM phosphate buffer	1137:1158	10 mM phosphate buffer	1137:1158	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	4	14	theme	AAV	445:447	arg1	formulations					449:460	AAV formulations	445:460	AAV formulations	445:460	Therefore, there is a need for AAV formulations, such as freeze-dried formulations, that allow for long-term storage at 2-8 °C.					
35259349	4	14	theme	AAV	445:447	arg1	formulations					484:495	freeze-dried formulations	471:495	freeze-dried formulations	471:495	Therefore, there is a need for AAV formulations, such as freeze-dried formulations, that allow for long-term storage at 2-8 °C.					
35259349	5	15	theme	AAV	641:643	arg1	vector					645:650	an AAV vector	638:650	an AAV vector	638:650	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	9	16	theme	vector-based	1431:1442	arg1	products					1457:1464	AAV vector-based gene therapy products	1427:1464	AAV vector-based gene therapy products	1427:1464	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	5	17	from	stress	671:676	arg1	capsid					685:690	the capsid	681:690	the capsid during the lyophilization cycle	681:722	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	5	18	theme	lyophilization	576:589	arg1	process					591:597	a lyophilization process	574:597	a lyophilization process for complex biological structures like an AAV vector	574:650	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	9	19	theme	gene	1444:1447	arg1	products					1457:1464	AAV vector-based gene therapy products	1427:1464	AAV vector-based gene therapy products	1427:1464	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	1	20	theme	promising	151:159	arg1	systems					170:176	the most promising delivery systems	142:176	the most promising delivery systems for gene therapy	142:193	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	3	21	theme	activity	334:341	arg1	loss					326:329	loss	326:329	loss of activity	326:341	While this allows for long-term vector storage without loss of activity, it is inconvenient and involves high costs and logistical challenges.					
35259349	7	22	theme	excipient	1082:1090	arg1	compositions					1092:1103	excipient compositions	1082:1103	excipient compositions	1082:1103	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	1	23	theme	Adeno-associated	82:97	arg1	AAV					106:108	AAV	106:108	AAV	106:108	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	1	23	theme	Adeno-associated	82:97	arg1	virus					99:103	Adeno-associated virus	82:103	Adeno-associated virus (AAV) vectors	82:117	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	1	24	theme	delivery	161:168	arg1	systems					170:176	the most promising delivery systems	142:176	the most promising delivery systems for gene therapy	142:193	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	4	25	from	2-8 °C	534:539	arg1	storage					523:529	long-term storage	513:529	long-term storage at 2-8 °C	513:539	Therefore, there is a need for AAV formulations, such as freeze-dried formulations, that allow for long-term storage at 2-8 °C.					
35259349	5	26	theme	complex	603:609	arg1	structures					622:631	complex biological structures	603:631	complex biological structures like an AAV vector	603:650	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	6	27	theme	different	744:752	arg1	conditions					754:763	different conditions	744:763	different conditions for freeze-drying of AAV8 vectors	744:797	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	1	28	theme	virus	99:103	arg1	vectors					111:117	Adeno-associated virus (AAV) vectors	82:117	Adeno-associated virus (AAV) vectors	82:117	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	1	29	theme	systems	170:176	arg1	systems					170:176	the most promising delivery systems	142:176	the most promising delivery systems for gene therapy	142:193	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	1	29	theme	systems	170:176	arg1	one					135:137	one	135:137	one	135:137	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	0	30	theme	Systematic	0:9	arg1	Studies					11:17	Systematic Studies	0:17	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization	0:79	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization.					
35259349	5	31	theme	biological	611:620	arg1	structures					622:631	complex biological structures	603:631	complex biological structures like an AAV vector	603:650	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	5	32	theme	major	544:548	arg1	challenge					550:558	A major challenge	542:558	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector	542:650	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	7	33	dep	found	1109:1113	arg1	combination					1122:1132	a combination	1120:1132	a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx	1120:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	4	34	theme	long-term	513:521	arg1	storage					523:529	long-term storage	513:529	long-term storage at 2-8 °C	513:539	Therefore, there is a need for AAV formulations, such as freeze-dried formulations, that allow for long-term storage at 2-8 °C.					
35259349	7	35	theme	approx	1252:1257	arg1	moisture					1240:1247	a residual moisture	1229:1247	a residual moisture of approx	1229:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	8	36	theme	long-term	1281:1289	arg1	storage					1291:1297	stable long-term storage	1274:1297	stable long-term storage	1274:1297	1.5% provided stable long-term storage at 2-8 °C and for at least 4 weeks at 25 °C.					
35259349	7	37	with	combination	1122:1132	arg1	moisture					1240:1247	a residual moisture	1229:1247	a residual moisture of approx	1229:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	1	38	theme	gene	182:185	arg1	therapy					187:193	gene therapy	182:193	gene therapy	182:193	Adeno-associated virus (AAV) vectors have evolved as one of the most promising delivery systems for gene therapy.					
35259349	7	39	theme	next	1009:1012	arg1	step					1014:1017	a next step	1007:1017	a next step	1007:1017	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	8	40	theme	stable	1274:1279	arg1	storage					1291:1297	stable long-term storage	1274:1297	stable long-term storage	1274:1297	1.5% provided stable long-term storage at 2-8 °C and for at least 4 weeks at 25 °C.					
35259349	7	41	theme	poloxamer	1214:1222	arg1	combination					1122:1132	a combination	1120:1132	a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx	1120:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	0	42	theme	AAV	39:41	arg1	Formulations					50:61	AAV Vector Formulations	39:61	AAV Vector Formulations	39:61	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization.					
35259349	7	43	theme	0.1	1209:1211	arg1	%					1212:1212	%	1212:1212	%	1212:1212	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	2	44	theme	AAV	221:223	arg1	storage					232:238	AAV vector storage	221:238	AAV vector storage	221:238	The current standard for AAV vector storage is deep-freezing below -60 °C.					
35259349	3	45	theme	logistical	391:400	arg1	challenges					402:411	logistical challenges	391:411	logistical challenges	391:411	While this allows for long-term vector storage without loss of activity, it is inconvenient and involves high costs and logistical challenges.					
35259349	7	46	dep	%	1165:1165	arg1	150 mM					1168:1173	150 mM	1168:1173	150 mM	1168:1173	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	7	47	theme	residual	1231:1238	arg1	moisture					1240:1247	a residual moisture	1229:1247	a residual moisture of approx	1229:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	5	48	theme	lyophilization	703:716	arg1	cycle					718:722	the lyophilization cycle	699:722	the lyophilization cycle	699:722	A major challenge in developing a lyophilization process for complex biological structures like an AAV vector is to minimize the stress on the capsid during the lyophilization cycle.					
35259349	0	49	theme	Formulations	50:61	arg1	Stabilization					22:34	Stabilization	22:34	Stabilization of AAV Vector Formulations by Lyophilization	22:79	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization.					
35259349	6	50	theme	undesirable	814:824	arg1	instability					826:836	undesirable instability	814:836	undesirable instability	814:836	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	7	51	theme	%	1188:1188	arg1	hydroxyectoine					1190:1203	5% hydroxyectoine	1187:1203	5% hydroxyectoine	1187:1203	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	0	52	theme	Vector	43:48	arg1	Formulations					50:61	AAV Vector Formulations	39:61	AAV Vector Formulations	39:61	Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization.					
35259349	3	53	theme	long-term	293:301	arg1	storage					310:316	long-term vector storage	293:316	long-term vector storage	293:316	While this allows for long-term vector storage without loss of activity, it is inconvenient and involves high costs and logistical challenges.					
35259349	7	54	theme	hydroxyectoine	1190:1203	arg1	combination					1122:1132	a combination	1120:1132	a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx	1120:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	6	55	theme	lower	903:907	arg1	temperatures					909:920	lower temperatures	903:920	lower temperatures	903:920	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	9	56	theme	freeze-drying	1399:1411	arg1	processes					1413:1421	freeze-drying processes	1399:1421	freeze-drying processes	1399:1421	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	9	57	theme	future	1375:1380	arg1	optimizations					1382:1394	future optimizations	1375:1394	future optimizations of freeze-drying processes	1375:1421	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	9	58	theme	therapy	1449:1455	arg1	products					1457:1464	AAV vector-based gene therapy products	1427:1464	AAV vector-based gene therapy products	1427:1464	These results pave the way for future optimizations of freeze-drying processes for AAV vector-based gene therapy products.					
35259349	7	59	theme	5	1187:1187	arg1	%					1188:1188	%	1188:1188	%	1188:1188	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	7	60	theme	5.67	1161:1164	arg1	%					1165:1165	%	1165:1165	%	1165:1165	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	6	61	theme	vectors	791:797	arg1	freeze-drying					769:781	freeze-drying	769:781	freeze-drying of AAV8 vectors	769:797	Here, we evaluated different conditions for freeze-drying of AAV8 vectors and found that undesirable instability can be significantly reduced if secondary drying is performed at lower temperatures, kept as short as possible, and the residual moisture is kept between 1.5 and 2%.					
35259349	7	62	theme	%	1212:1212	arg1	poloxamer					1214:1222	0.1% poloxamer	1209:1222	0.1% poloxamer	1209:1222	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	7	63	theme	%	1165:1165	arg1	trehalose					1176:1184	5.67% (150 mM) trehalose	1161:1184	5.67% (150 mM) trehalose	1161:1184	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
35259349	3	64	theme	high	376:379	arg1	costs					381:385	high costs	376:385	high costs	376:385	While this allows for long-term vector storage without loss of activity, it is inconvenient and involves high costs and logistical challenges.					
35259349	2	65	theme	vector	225:230	arg1	storage					232:238	AAV vector storage	221:238	AAV vector storage	221:238	The current standard for AAV vector storage is deep-freezing below -60 °C.					
35259349	7	66	theme	trehalose	1176:1184	arg1	combination					1122:1132	a combination	1120:1132	a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx	1120:1257	In a next step, we explored formulations with different salt concentration or excipient compositions and found that a combination of 10 mM phosphate buffer, 5.67% (150 mM) trehalose, 5% hydroxyectoine and 0.1% poloxamer with a residual moisture of approx.					
36038969	9	0	theme	foam	1228:1231	arg1	mechanism					1211:1219	The main mechanism	1202:1219	The main mechanism of the foam	1202:1231	The main mechanism of the foam is ion exchange.					
36038969	9	0	theme	foam	1228:1231	arg1	exchange					1240:1247	ion exchange	1236:1247	ion exchange	1236:1247	The main mechanism of the foam is ion exchange.					
36038969	5	1	theme	maximal	687:693	arg1	capacity					719:726	the maximal fluoride ion adsorption capacity	683:726	the maximal fluoride ion adsorption capacity	683:726	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	1	theme	maximal	687:693	arg1	mg/g					737:740	5.09 mg/g	732:740	5.09 mg/g with 20 mg/L fluorine solutions	732:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	2	theme	fluoride	695:702	arg1	capacity					719:726	the maximal fluoride ion adsorption capacity	683:726	the maximal fluoride ion adsorption capacity	683:726	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	2	theme	fluoride	695:702	arg1	mg/g					737:740	5.09 mg/g	732:740	5.09 mg/g with 20 mg/L fluorine solutions	732:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	0	3	theme	ion	79:81	arg1	removal					83:89	fluoride ion removal	70:89	fluoride ion removal	70:89	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	9	4	theme	ion	1236:1238	arg1	mechanism					1211:1219	The main mechanism	1202:1219	The main mechanism of the foam	1202:1231	The main mechanism of the foam is ion exchange.					
36038969	9	4	theme	ion	1236:1238	arg1	exchange					1240:1247	ion exchange	1236:1247	ion exchange	1236:1247	The main mechanism of the foam is ion exchange.					
36038969	7	5	theme	pseudo-second-order	1014:1032	arg1	model					1034:1038	a pseudo-second-order model	1012:1038	a pseudo-second-order model	1012:1038	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	2	6	theme	dental	251:256	arg1	fluorosis					258:266	dental fluorosis	251:266	dental fluorosis	251:266	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	6	7	theme	adsorption	890:899	arg1	process					901:907	the adsorption process	886:907	the adsorption process	886:907	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	6	7	theme	adsorption	890:899	arg1	closer					912:917	closer	912:917	closer	912:917	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	0	8	theme	fluoride	70:77	arg1	removal					83:89	fluoride ion removal	70:89	fluoride ion removal	70:89	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	6	9	theme	adsorption	792:801	arg1	isotherm					803:810	The adsorption isotherm	788:810	The adsorption isotherm	788:810	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	5	10	theme	adsorption	652:661	arg1	results					663:669	The adsorption results	648:669	The adsorption results	648:669	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	11	theme	ion	704:706	arg1	capacity					719:726	the maximal fluoride ion adsorption capacity	683:726	the maximal fluoride ion adsorption capacity	683:726	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	11	theme	ion	704:706	arg1	mg/g					737:740	5.09 mg/g	732:740	5.09 mg/g with 20 mg/L fluorine solutions	732:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	7	12	theme	adsorption	1049:1058	arg1	process					1060:1066	the adsorption process	1045:1066	the adsorption process	1045:1066	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	3	13	theme	-based	341:346	arg1	materials					353:361	sodium alginate (SA)-based foam materials	321:361	sodium alginate (SA)-based foam materials	321:361	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	2	14	theme	skeletal	228:235	arg1	fluorosis					237:245	skeletal fluorosis	228:245	skeletal fluorosis	228:245	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	8	15	theme	Adsorption	1095:1104	arg1	analysis					1121:1128	Adsorption thermodynamics analysis	1095:1128	Adsorption thermodynamics analysis	1095:1128	Adsorption thermodynamics analysis emphasized that the adsorption process was spontaneous and endothermic.					
36038969	2	16	theme	human	280:284	arg1	health					286:291	human health	280:291	human health	280:291	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	3	17	theme	materials	353:361	arg1	series					311:316	a series	309:316	a series of sodium alginate (SA)-based foam materials	309:361	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	0	18	theme	Tailored	0:7	arg1	design					9:14	Tailored design	0:14	Tailored design of a novel composite foam of sodium alginate	0:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	10	19	theme	SA-nAl2O3	1254:1262	arg1	foam					1264:1267	The SA-nAl2O3 foam	1250:1267	The SA-nAl2O3 foam	1250:1267	The SA-nAl2O3 foam exhibited excellent regeneration performance and stability after three cycles.					
36038969	7	20	theme	SA-nAl2O3	980:988	arg1	foam					990:993	SA-nAl2O3 foam	980:993	SA-nAl2O3 foam	980:993	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	3	21	from	alumina	440:446	arg1	SA					464:465	the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal	460:542	the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal	460:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	8	22	theme	adsorption	1150:1159	arg1	spontaneous					1173:1183	spontaneous	1173:1183	spontaneous	1173:1183	Adsorption thermodynamics analysis emphasized that the adsorption process was spontaneous and endothermic.					
36038969	8	22	theme	adsorption	1150:1159	arg1	process					1161:1167	the adsorption process	1146:1167	the adsorption process	1146:1167	Adsorption thermodynamics analysis emphasized that the adsorption process was spontaneous and endothermic.					
36038969	4	23	theme	SA-nAl2O3	549:557	arg1	morphology					564:573	The SA-nAl2O3 foam morphology	545:573	The SA-nAl2O3 foam morphology	545:573	The SA-nAl2O3 foam morphology was further explored and confirmed that nAl2O3 existed stably in the SA.					
36038969	7	24	theme	foam	990:993	arg1	behavior					968:975	The adsorption kinetics behavior	944:975	The adsorption kinetics behavior of SA-nAl2O3 foam	944:993	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	0	25	used	used	61:64	arg2	design					9:14	Tailored design	0:14	Tailored design of a novel composite foam of sodium alginate	0:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	3	26	theme	novel	479:483	arg1	foam					508:511	a novel adsorbent of SA-nAl2O3 foam	477:511	a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal	477:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	5	27	theme	mg/L	750:753	arg1	solutions					764:772	20 mg/L fluorine solutions	747:772	20 mg/L fluorine solutions	747:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	0	28	theme	composite	27:35	arg1	foam					37:40	a novel composite foam	19:40	a novel composite foam of sodium alginate	19:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	5	29	theme	fluorine	755:762	arg1	solutions					764:772	20 mg/L fluorine solutions	747:772	20 mg/L fluorine solutions	747:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	3	30	theme	freeze-drying	379:391	arg1	technique					393:401	freeze-drying technique	379:401	freeze-drying technique	379:401	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	0	31	theme	novel	21:25	arg1	foam					37:40	a novel composite foam	19:40	a novel composite foam of sodium alginate	19:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	3	32	theme	foam	348:351	arg1	materials					353:361	sodium alginate (SA)-based foam materials	321:361	sodium alginate (SA)-based foam materials	321:361	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	10	33	theme	regeneration	1289:1300	arg1	performance					1302:1312	excellent regeneration performance	1279:1312	excellent regeneration performance	1279:1312	The SA-nAl2O3 foam exhibited excellent regeneration performance and stability after three cycles.					
36038969	4	34	theme	foam	559:562	arg1	morphology					564:573	The SA-nAl2O3 foam morphology	545:573	The SA-nAl2O3 foam morphology	545:573	The SA-nAl2O3 foam morphology was further explored and confirmed that nAl2O3 existed stably in the SA.					
36038969	5	35	theme	adsorption	708:717	arg1	capacity					719:726	the maximal fluoride ion adsorption capacity	683:726	the maximal fluoride ion adsorption capacity	683:726	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	35	theme	adsorption	708:717	arg1	mg/g					737:740	5.09 mg/g	732:740	5.09 mg/g with 20 mg/L fluorine solutions	732:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	6	36	theme	isotherm	846:853	arg1	model					855:859	the Langmuir isotherm model	833:859	the Langmuir isotherm model	833:859	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	7	37	theme	adsorption	948:957	arg1	behavior					968:975	The adsorption kinetics behavior	944:975	The adsorption kinetics behavior of SA-nAl2O3 foam	944:993	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	3	38	theme	SA-nAl2O3	498:506	arg1	adsorbent					485:493	adsorbent	485:493	adsorbent	485:493	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	10	39	theme	excellent	1279:1287	arg1	performance					1302:1312	excellent regeneration performance	1279:1312	excellent regeneration performance	1279:1312	The SA-nAl2O3 foam exhibited excellent regeneration performance and stability after three cycles.					
36038969	3	40	theme	nano-activated	425:438	arg1	nAl2O3					449:454	nAl2O3	449:454	nAl2O3	449:454	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	3	40	theme	nano-activated	425:438	arg1	alumina					440:446	the nano-activated alumina	421:446	the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal	421:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	0	41	theme	foam	37:40	arg1	design					9:14	Tailored design	0:14	Tailored design of a novel composite foam of sodium alginate	0:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	6	42	theme	Langmuir	837:844	arg1	model					855:859	the Langmuir isotherm model	833:859	the Langmuir isotherm model	833:859	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	7	43	theme	kinetics	959:966	arg1	behavior					968:975	The adsorption kinetics behavior	944:975	The adsorption kinetics behavior of SA-nAl2O3 foam	944:993	The adsorption kinetics behavior of SA-nAl2O3 foam was described by a pseudo-second-order model, and the adsorption process occurred by chemisorption.					
36038969	2	44	theme	ion	184:186	arg1	amount					165:170	the amount	161:170	the amount of fluoride ion	161:186	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	2	44	theme	ion	184:186	arg1	ion					184:186	fluoride ion	175:186	fluoride ion	175:186	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	9	45	theme	main	1206:1209	arg1	mechanism					1211:1219	The main mechanism	1202:1219	The main mechanism of the foam	1202:1231	The main mechanism of the foam is ion exchange.					
36038969	9	45	theme	main	1206:1209	arg1	exchange					1240:1247	ion exchange	1236:1247	ion exchange	1236:1247	The main mechanism of the foam is ion exchange.					
36038969	3	46	theme	adsorbent	485:493	arg1	foam					508:511	a novel adsorbent of SA-nAl2O3 foam	477:511	a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal	477:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	2	47	theme	fluoride	175:182	arg1	ion					184:186	fluoride ion	175:186	fluoride ion	175:186	Nonetheless, when the amount of fluoride ion is greater than required, it will cause skeletal fluorosis and dental fluorosis to threaten human health.					
36038969	5	48	with	mg/g	737:740	arg1	solutions					764:772	20 mg/L fluorine solutions	747:772	20 mg/L fluorine solutions	747:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	8	49	theme	thermodynamics	1106:1119	arg1	analysis					1121:1128	Adsorption thermodynamics analysis	1095:1128	Adsorption thermodynamics analysis	1095:1128	Adsorption thermodynamics analysis emphasized that the adsorption process was spontaneous and endothermic.					
36038969	5	50	from	pH	779:780	arg1	capacity					719:726	the maximal fluoride ion adsorption capacity	683:726	the maximal fluoride ion adsorption capacity	683:726	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	50	from	pH	779:780	arg1	mg/g					737:740	5.09 mg/g	732:740	5.09 mg/g with 20 mg/L fluorine solutions	732:772	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	1	51	theme	essential	107:115	arg1	Fluoride					92:99	Fluoride	92:99	Fluoride	92:99	Fluoride is an essential micronutrient for humans.					
36038969	1	51	theme	essential	107:115	arg1	micronutrient					117:129	an essential micronutrient	104:129	an essential micronutrient for humans	104:140	Fluoride is an essential micronutrient for humans.					
36038969	6	52	theme	monolayer	922:930	arg1	adsorption					932:941	monolayer adsorption	922:941	monolayer adsorption	922:941	The adsorption isotherm fitted adequately to the Langmuir isotherm model, which demonstrated that the adsorption process is closer to monolayer adsorption.					
36038969	0	53	theme	alginate	52:59	arg1	foam					37:40	a novel composite foam	19:40	a novel composite foam of sodium alginate	19:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	3	54	theme	fluoride	522:529	arg1	ions					531:534	fluoride ions	522:534	fluoride ions removal	522:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
36038969	5	55	theme	20	747:748	arg1	mg/L					750:753	mg/L	750:753	mg/L	750:753	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	5	56	theme	3	785:785	arg1	pH					779:780	a pH	777:780	a pH of 3	777:785	The adsorption results showed that the maximal fluoride ion adsorption capacity was 5.09 mg/g with 20 mg/L fluorine solutions at a pH of 3.					
36038969	0	57	theme	sodium	45:50	arg1	alginate					52:59	sodium alginate	45:59	sodium alginate	45:59	Tailored design of a novel composite foam of sodium alginate used for fluoride ion removal.					
36038969	3	58	theme	ions	531:534	arg1	removal					536:542	fluoride ions removal	522:542	fluoride ions removal	522:542	In this paper, a series of sodium alginate (SA)-based foam materials are prepared by freeze-drying technique and anchored with the nano-activated alumina (nAl2O3) in the SA to obtain a novel adsorbent of SA-nAl2O3 foam used for fluoride ions removal.					
37068561	4	0	theme	optimum	728:734	arg1	formulation					736:746	an optimum formulation	725:746	an optimum formulation for further in vivo inspection	725:777	Afterward, three promising formulations were loaded with berberine and characterized to select an optimum formulation for further in vivo inspection.					
37068561	5	1	theme	particle	798:805	arg1	size					807:810	particle size	798:810	particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39	798:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	7	2	theme	hippocampal	1115:1125	arg1	tissue					1127:1132	The hippocampal tissue	1111:1132	The hippocampal tissue of rats receiving B2	1111:1153	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	6	3	from	severity	994:1001	arg1	rats					1048:1051	rats	1048:1051	rats	1048:1051	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	1	4	theme	plant	188:192	arg1	alkaloid					194:201	a plant alkaloid	186:201	a plant alkaloid with versatile medicinal applications	186:239	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	1	4	theme	plant	188:192	arg1	hydrochloride					169:181	Berberine hydrochloride	159:181	Berberine hydrochloride	159:181	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	7	5	theme	lower	1210:1214	arg1	levels					1227:1232	remarkably lower expression levels	1199:1232	remarkably lower expression levels of COX-2 and TNF-α	1199:1251	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	8	6	theme	changes	1416:1422	arg1	sign					1381:1384	any sign	1377:1384	any sign of intoxication or behavioral changes	1377:1422	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	9	7	theme	deteriorating	1570:1582	arg1	impact					1584:1589	the deteriorating impact	1566:1589	the deteriorating impact of pilocarpine-induced epilepsy	1566:1621	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	4	8	dep	in	760:761	arg1	vivo					763:766	vivo	763:766	vivo	763:766	Afterward, three promising formulations were loaded with berberine and characterized to select an optimum formulation for further in vivo inspection.					
37068561	6	9	theme	berberine	968:976	arg1	suspension					978:987	free berberine suspension	963:987	free berberine suspension	963:987	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	7	10	theme	TNF-α	1247:1251	arg1	activity					1279:1286	enhanced antioxidant activity	1258:1286	enhanced antioxidant activity	1258:1286	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	10	theme	TNF-α	1247:1251	arg1	levels					1227:1232	remarkably lower expression levels	1199:1232	remarkably lower expression levels of COX-2 and TNF-α	1199:1251	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	10	theme	TNF-α	1247:1251	arg1	signs					1162:1166	signs	1162:1166	signs of reduced neuro-degeneration	1162:1196	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	4	11	theme	further	752:758	arg1	inspection					768:777	further in vivo inspection	752:777	further in vivo inspection	752:777	Afterward, three promising formulations were loaded with berberine and characterized to select an optimum formulation for further in vivo inspection.					
37068561	5	12	theme	efficiency	848:857	arg1	size					807:810	particle size	798:810	particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39	798:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	5	13	theme	brain	914:918	arg1	uptake					920:925	the brain uptake	910:925	the brain uptake of berberine	910:938	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	2	14	theme	capable	419:425	arg1	nanosystem					408:417	a nanosystem	406:417	a nanosystem capable of delivering it safely and efficiently to the brain	406:478	Nonetheless, the acknowledged role of berberine in controlling seizures has fuelled the need to develop a nanosystem capable of delivering it safely and efficiently to the brain.					
37068561	0	15	theme	pilocarpine	128:138	arg1	model					140:144	the pilocarpine model	124:144	the pilocarpine model of epilepsy	124:156	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	0	16	theme	Berberine-loaded	0:15	arg1	composite					38:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	5	17	theme	±	869:869	arg1	1.39					871:874	83.75% ± 1.39	862:874	83.75% ± 1.39	862:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	0	18	theme	zein/hyaluronic	17:31	arg1	composite					38:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	6	19	theme	epilepticus	1033:1043	arg1	severity					994:1001	the severity	990:1001	the severity of pilocarpine-induced status epilepticus in rats	990:1051	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	6	20	theme	subcutaneous	1076:1087	arg1	administration					1089:1102	the subcutaneous administration	1072:1102	the subcutaneous administration of B2	1072:1108	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	7	21	theme	COX-2	1237:1241	arg1	activity					1279:1286	enhanced antioxidant activity	1258:1286	enhanced antioxidant activity	1258:1286	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	21	theme	COX-2	1237:1241	arg1	levels					1227:1232	remarkably lower expression levels	1199:1232	remarkably lower expression levels of COX-2 and TNF-α	1199:1251	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	21	theme	COX-2	1237:1241	arg1	signs					1162:1166	signs	1162:1166	signs of reduced neuro-degeneration	1162:1196	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	2	22	theme	berberine	340:348	arg1	role					332:335	the acknowledged role	315:335	the acknowledged role of berberine in controlling seizures	315:372	Nonetheless, the acknowledged role of berberine in controlling seizures has fuelled the need to develop a nanosystem capable of delivering it safely and efficiently to the brain.					
37068561	7	23	theme	reduced	1171:1177	arg1	neuro-degeneration					1179:1196	reduced neuro-degeneration	1171:1196	reduced neuro-degeneration	1171:1196	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	1	24	theme	versatile	208:216	arg1	applications					228:239	versatile medicinal applications	208:239	versatile medicinal applications	208:239	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	3	25	with	formulations	567:578	arg1	factors					607:613	different preliminary factors	585:613	different preliminary factors	585:613	Consequently, zein and hyaluronic acid were chosen for this purpose, and about twenty formulations with different preliminary factors were screened.					
37068561	6	26	theme	free	963:966	arg1	suspension					978:987	free berberine suspension	963:987	free berberine suspension	963:987	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	3	27	theme	different	585:593	arg1	factors					607:613	different preliminary factors	585:613	different preliminary factors	585:613	Consequently, zein and hyaluronic acid were chosen for this purpose, and about twenty formulations with different preliminary factors were screened.					
37068561	1	28	theme	medicinal	218:226	arg1	applications					228:239	versatile medicinal applications	208:239	versatile medicinal applications	208:239	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	0	29	theme	epilepsy	149:156	arg1	model					140:144	the pilocarpine model	124:144	the pilocarpine model of epilepsy	124:156	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	5	30	theme	uptake	920:925	arg1	increment					897:905	the increment	893:905	the increment of the brain uptake of berberine	893:938	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	8	31	theme	developed	1325:1333	arg1	system					1335:1340	the developed system	1321:1340	the developed system	1321:1340	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	5	32	theme	entrapment	837:846	arg1	efficiency					848:857	% entrapment efficiency	835:857	% entrapment efficiency	835:857	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	0	33	theme	acid	33:36	arg1	composite					38:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite	0:46	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	5	34	theme	berberine	930:938	arg1	uptake					920:925	the brain uptake	910:925	the brain uptake of berberine	910:938	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	2	35	theme	acknowledged	319:330	arg1	role					332:335	the acknowledged role	315:335	the acknowledged role of berberine in controlling seizures	315:372	Nonetheless, the acknowledged role of berberine in controlling seizures has fuelled the need to develop a nanosystem capable of delivering it safely and efficiently to the brain.					
37068561	4	36	theme	promising	647:655	arg1	formulations					657:668	three promising formulations	641:668	three promising formulations	641:668	Afterward, three promising formulations were loaded with berberine and characterized to select an optimum formulation for further in vivo inspection.					
37068561	5	37	theme	size	807:810	arg1	formula					787:793	The B2 formula	780:793	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39	780:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	9	38	theme	epilepsy	1614:1621	arg1	impact					1584:1589	the deteriorating impact	1566:1589	the deteriorating impact of pilocarpine-induced epilepsy	1566:1621	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	7	39	theme	neuro-degeneration	1179:1196	arg1	activity					1279:1286	enhanced antioxidant activity	1258:1286	enhanced antioxidant activity	1258:1286	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	39	theme	neuro-degeneration	1179:1196	arg1	levels					1227:1232	remarkably lower expression levels	1199:1232	remarkably lower expression levels of COX-2 and TNF-α	1199:1251	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	39	theme	neuro-degeneration	1179:1196	arg1	signs					1162:1166	signs	1162:1166	signs of reduced neuro-degeneration	1162:1196	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	9	40	theme	loaded	1464:1469	arg1	nanoparticles					1481:1493	the developed berberine loaded composite nanoparticles	1440:1493	the developed berberine loaded composite nanoparticles	1440:1493	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	7	41	theme	rats	1137:1140	arg1	tissue					1127:1132	The hippocampal tissue	1111:1132	The hippocampal tissue of rats receiving B2	1111:1153	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	5	42	theme	%	867:867	arg1	1.39					871:874	83.75% ± 1.39	862:874	83.75% ± 1.39	862:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	5	43	theme	1.39	871:874	arg1	efficiency					848:857	% entrapment efficiency	835:857	% entrapment efficiency	835:857	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	5	43	theme	1.39	871:874	arg1	±					824:824	± 1.86	824:829	± 1.86	824:829	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	8	44	theme	intoxication	1389:1400	arg1	sign					1381:1384	any sign	1377:1384	any sign of intoxication or behavioral changes	1377:1422	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	5	45	theme	83.75	862:866	arg1	%					867:867	%	867:867	%	867:867	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	0	46	theme	brain	76:80	arg1	uptake					82:87	efficient brain uptake	66:87	efficient brain uptake	66:87	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	9	47	theme	developed	1444:1452	arg1	nanoparticles					1481:1493	the developed berberine loaded composite nanoparticles	1440:1493	the developed berberine loaded composite nanoparticles	1440:1493	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	5	48	theme	nm	821:822	arg1	±					824:824	± 1.86	824:829	± 1.86	824:829	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	3	49	theme	preliminary	595:605	arg1	factors					607:613	different preliminary factors	585:613	different preliminary factors	585:613	Consequently, zein and hyaluronic acid were chosen for this purpose, and about twenty formulations with different preliminary factors were screened.					
37068561	3	50	theme	hyaluronic	504:513	arg1	acid					515:518	hyaluronic acid	504:518	hyaluronic acid	504:518	Consequently, zein and hyaluronic acid were chosen for this purpose, and about twenty formulations with different preliminary factors were screened.					
37068561	0	51	theme	efficient	66:74	arg1	uptake					82:87	efficient brain uptake	66:87	efficient brain uptake	66:87	Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy.					
37068561	8	52	theme	behavioral	1405:1414	arg1	changes					1416:1422	behavioral changes	1405:1422	behavioral changes	1405:1422	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	7	53	theme	expression	1216:1225	arg1	levels					1227:1232	remarkably lower expression levels	1199:1232	remarkably lower expression levels of COX-2 and TNF-α	1199:1251	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	7	54	theme	enhanced	1258:1265	arg1	activity					1279:1286	enhanced antioxidant activity	1258:1286	enhanced antioxidant activity	1258:1286	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	1	55	with	alkaloid	194:201	arg1	applications					228:239	versatile medicinal applications	208:239	versatile medicinal applications	208:239	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	6	56	theme	pilocarpine-induced	1006:1024	arg1	epilepticus					1033:1043	pilocarpine-induced status epilepticus	1006:1043	pilocarpine-induced status epilepticus	1006:1043	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	2	57	theme	controlling	353:363	arg1	seizures					365:372	controlling seizures	353:372	controlling seizures	353:372	Nonetheless, the acknowledged role of berberine in controlling seizures has fuelled the need to develop a nanosystem capable of delivering it safely and efficiently to the brain.					
37068561	6	58	theme	status	1026:1031	arg1	epilepticus					1033:1043	pilocarpine-induced status epilepticus	1006:1043	pilocarpine-induced status epilepticus	1006:1043	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	9	59	theme	pilocarpine-induced	1594:1612	arg1	epilepsy					1614:1621	pilocarpine-induced epilepsy	1594:1621	pilocarpine-induced epilepsy	1594:1621	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	1	60	theme	Berberine	159:167	arg1	alkaloid					194:201	a plant alkaloid	186:201	a plant alkaloid with versatile medicinal applications	186:239	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	1	60	theme	Berberine	159:167	arg1	hydrochloride					169:181	Berberine hydrochloride	159:181	Berberine hydrochloride	159:181	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
37068561	8	61	theme	system	1335:1340	arg1	safety					1311:1316	the relative safety	1298:1316	the relative safety of the developed system	1298:1340	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	4	62	theme	in	760:761	arg1	inspection					768:777	further in vivo inspection	752:777	further in vivo inspection	752:777	Afterward, three promising formulations were loaded with berberine and characterized to select an optimum formulation for further in vivo inspection.					
37068561	5	63	theme	B2	784:785	arg1	formula					787:793	The B2 formula	780:793	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39	780:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	6	64	theme	B2	1107:1108	arg1	administration					1089:1102	the subcutaneous administration	1072:1102	the subcutaneous administration of B2	1072:1108	Moreover, compared to free berberine suspension, the severity of pilocarpine-induced status epilepticus in rats was depleted after the subcutaneous administration of B2.					
37068561	9	65	theme	composite	1471:1479	arg1	nanoparticles					1481:1493	the developed berberine loaded composite nanoparticles	1440:1493	the developed berberine loaded composite nanoparticles	1440:1493	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	8	66	theme	relative	1302:1309	arg1	safety					1311:1316	the relative safety	1298:1316	the relative safety of the developed system	1298:1340	Finally, the relative safety of the developed system was determined after searching for any sign of intoxication or behavioral changes.					
37068561	5	67	theme	297.2	815:819	arg1	nm					821:822	nm	821:822	nm	821:822	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	9	68	theme	berberine	1454:1462	arg1	nanoparticles					1481:1493	the developed berberine loaded composite nanoparticles	1440:1493	the developed berberine loaded composite nanoparticles	1440:1493	In conclusion, the developed berberine loaded composite nanoparticles successfully delivered berberine across the BBB securely to ameliorate the deteriorating impact of pilocarpine-induced epilepsy.					
37068561	5	69	theme	%	835:835	arg1	efficiency					848:857	% entrapment efficiency	835:857	% entrapment efficiency	835:857	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	7	70	theme	antioxidant	1267:1277	arg1	activity					1279:1286	enhanced antioxidant activity	1258:1286	enhanced antioxidant activity	1258:1286	The hippocampal tissue of rats receiving B2 showed signs of reduced neuro-degeneration, remarkably lower expression levels of COX-2 and TNF-α, and enhanced antioxidant activity.					
37068561	5	71	theme	±	824:824	arg1	size					807:810	particle size	798:810	particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39	798:874	The B2 formula of particle size of 297.2 nm ± 1.86 and % entrapment efficiency of 83.75% ± 1.39 has succeeded in the increment of the brain uptake of berberine.					
37068561	2	72	from	role	332:335	arg1	seizures					365:372	controlling seizures	353:372	controlling seizures	353:372	Nonetheless, the acknowledged role of berberine in controlling seizures has fuelled the need to develop a nanosystem capable of delivering it safely and efficiently to the brain.					
37068561	1	73	theme	multiple	267:274	arg1	limitations					276:286	multiple limitations	267:286	multiple limitations	267:286	Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has suffered from multiple limitations in its usage.					
36167104	8	0	theme	starch/PVA	1216:1225	arg1	films					1227:1231	the starch/PVA films	1212:1231	the starch/PVA films embedded with Ag-ZrP	1212:1252	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	6	1	theme	PVA	937:939	arg1	crystallinity					920:932	the crystallinity	916:932	the crystallinity of PVA	916:939	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	3	2	theme	hydrophobic	527:537	arg1	properties					557:566	the hydrophobic and antibacterial properties	523:566	the hydrophobic and antibacterial properties of the constructed nanofibrous films	523:603	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	5	3	theme	enhanced	835:842	arg1	strength					855:862	enhanced mechanical strength	835:862	enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite	835:903	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	6	4	theme	electrospinning	964:978	arg1	process					980:986	the electrospinning process	960:986	the electrospinning process	960:986	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	8	5	theme	Gram-negative	1306:1318	arg1	bacteria					1338:1345	both Gram-negative and Gram-positive bacteria	1301:1345	both Gram-negative and Gram-positive bacteria	1301:1345	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	1	6	theme	green	173:177	arg1	resources					179:187	green resources	173:187	green resources	173:187	Polymers synthesized from green resources have many advantages in food packaging and hence their development is very important.					
36167104	9	7	theme	starch	1410:1415	arg1	films					1429:1433	electrospun starch nanofibrous films	1398:1433	electrospun starch nanofibrous films	1398:1433	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	3	8	theme	constructed	575:585	arg1	films					599:603	the constructed nanofibrous films	571:603	the constructed nanofibrous films	571:603	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	4	9	theme	starch/PVA	635:644	arg1	ratio					646:650	starch/PVA ratio	635:650	starch/PVA ratio	635:650	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	0	10	theme	hydrophobic	85:95	arg1	property					97:104	hydrophobic property	85:104	hydrophobic property	85:104	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	10	theme	hydrophobic	85:95	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	9	11	theme	nanofibrous	1417:1427	arg1	films					1429:1433	electrospun starch nanofibrous films	1398:1433	electrospun starch nanofibrous films	1398:1433	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	2	12	theme	alcohol	300:306	arg1	films					336:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	Herein, starch/polyvinyl alcohol (PVA) nanofibrous composite films were fabricated by electrospinning technology.					
36167104	3	13	theme	nanofibrous	587:597	arg1	films					599:603	the constructed nanofibrous films	571:603	the constructed nanofibrous films	571:603	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	8	14	theme	outstanding	1258:1268	arg1	property					1284:1291	outstanding antibacterial property	1258:1291	outstanding antibacterial property	1258:1291	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	4	15	from	effects	624:630	arg1	properties					691:700	the micro-morphology and mechanical properties	655:700	the micro-morphology and mechanical properties of the binary composite film	655:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	9	16	theme	films	1429:1433	arg1	prospects					1385:1393	the potential prospects	1371:1393	the potential prospects of electrospun starch nanofibrous films in the food packaging field	1371:1461	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	7	17	theme	starch/PVA	1157:1166	arg1	films					1168:1172	the starch/PVA films	1153:1172	the starch/PVA films	1153:1172	After the cross-linking with GTA, the starch/PVA films became more hydrophobic.					
36167104	7	18	with	cross-linking	1129:1141	arg1	GTA					1148:1150	GTA	1148:1150	GTA	1148:1150	After the cross-linking with GTA, the starch/PVA films became more hydrophobic.					
36167104	2	19	theme	starch/polyvinyl	283:298	arg1	alcohol					300:306	starch/polyvinyl alcohol	283:306	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	Herein, starch/polyvinyl alcohol (PVA) nanofibrous composite films were fabricated by electrospinning technology.					
36167104	2	19	theme	starch/polyvinyl	283:298	arg1	PVA					309:311	PVA	309:311	PVA	309:311	Herein, starch/polyvinyl alcohol (PVA) nanofibrous composite films were fabricated by electrospinning technology.					
36167104	1	20	theme	many	194:197	arg1	advantages					199:208	many advantages	194:208	many advantages	194:208	Polymers synthesized from green resources have many advantages in food packaging and hence their development is very important.					
36167104	3	21	theme	zirconium	470:478	arg1	Ag-ZrP					491:496	Ag-ZrP	491:496	Ag-ZrP	491:496	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	21	theme	zirconium	470:478	arg1	phosphate					480:488	silver sodium zirconium phosphate	456:488	silver sodium zirconium phosphate (Ag-ZrP)	456:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	5	22	theme	electrospun	806:816	arg1	uniformity					784:793	optimal uniformity	776:793	optimal uniformity	776:793	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	5	22	theme	electrospun	806:816	arg1	nanofibers					818:827	bead-free electrospun nanofibers	796:827	bead-free electrospun nanofibers	796:827	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	5	23	theme	bead-free	796:804	arg1	uniformity					784:793	optimal uniformity	776:793	optimal uniformity	776:793	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	5	23	theme	bead-free	796:804	arg1	nanofibers					818:827	bead-free electrospun nanofibers	796:827	bead-free electrospun nanofibers	796:827	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	0	24	theme	starch	9:14	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	24	theme	starch	9:14	arg1	construction					71:82	Facile construction	64:82	Facile construction	64:82	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	24	theme	starch	9:14	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	24	theme	starch	9:14	arg1	property					97:104	hydrophobic property	85:104	hydrophobic property	85:104	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	6	25	theme	PVA	1017:1019	arg1	introduction					1001:1012	the introduction	997:1012	the introduction of PVA	997:1019	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	9	26	theme	food	1442:1445	arg1	field					1457:1461	the food packaging field	1438:1461	the food packaging field	1438:1461	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	2	27	theme	composite	326:334	arg1	films					336:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	Herein, starch/polyvinyl alcohol (PVA) nanofibrous composite films were fabricated by electrospinning technology.					
36167104	3	28	theme	silver	456:461	arg1	Ag-ZrP					491:496	Ag-ZrP	491:496	Ag-ZrP	491:496	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	28	theme	silver	456:461	arg1	phosphate					480:488	silver sodium zirconium phosphate	456:488	silver sodium zirconium phosphate (Ag-ZrP)	456:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	9	29	theme	electrospun	1398:1408	arg1	films					1429:1433	electrospun starch nanofibrous films	1398:1433	electrospun starch nanofibrous films	1398:1433	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	6	30	theme	hydrogen	1038:1045	arg1	interactions					1047:1058	the hydrogen interactions	1034:1058	the hydrogen interactions	1034:1058	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	8	31	with	embedded	1233:1240	arg1	Ag-ZrP					1247:1252	Ag-ZrP	1247:1252	Ag-ZrP	1247:1252	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	2	32	theme	nanofibrous	314:324	arg1	films					336:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	starch/polyvinyl alcohol (PVA) nanofibrous composite films	283:340	Herein, starch/polyvinyl alcohol (PVA) nanofibrous composite films were fabricated by electrospinning technology.					
36167104	3	33	theme	sodium	463:468	arg1	Ag-ZrP					491:496	Ag-ZrP	491:496	Ag-ZrP	491:496	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	33	theme	sodium	463:468	arg1	phosphate					480:488	silver sodium zirconium phosphate	456:488	silver sodium zirconium phosphate (Ag-ZrP)	456:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	0	34	theme	nanofibrous	26:36	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	34	theme	nanofibrous	26:36	arg1	construction					71:82	Facile construction	64:82	Facile construction	64:82	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	34	theme	nanofibrous	26:36	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	34	theme	nanofibrous	26:36	arg1	property					97:104	hydrophobic property	85:104	hydrophobic property	85:104	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	9	35	theme	packaging	1447:1455	arg1	field					1457:1461	the food packaging field	1438:1461	the food packaging field	1438:1461	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	0	36	theme	activity	125:132	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	36	theme	activity	125:132	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	3	37	theme	films	599:603	arg1	properties					557:566	the hydrophobic and antibacterial properties	523:566	the hydrophobic and antibacterial properties of the constructed nanofibrous films	523:603	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	4	38	theme	mechanical	680:689	arg1	properties					691:700	the micro-morphology and mechanical properties	655:700	the micro-morphology and mechanical properties of the binary composite film	655:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	0	39	theme	composite	16:24	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	39	theme	composite	16:24	arg1	construction					71:82	Facile construction	64:82	Facile construction	64:82	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	39	theme	composite	16:24	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	39	theme	composite	16:24	arg1	property					97:104	hydrophobic property	85:104	hydrophobic property	85:104	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	40	theme	antibacterial	111:123	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	40	theme	antibacterial	111:123	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	3	41	with	reaction	417:424	arg1	phosphate					480:488	silver sodium zirconium phosphate	456:488	silver sodium zirconium phosphate (Ag-ZrP)	456:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	41	with	reaction	417:424	arg1	GTA					447:449	GTA	447:449	GTA	447:449	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	41	with	reaction	417:424	arg1	glutaraldehyde					431:444	glutaraldehyde	431:444	glutaraldehyde (GTA)	431:450	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	3	41	with	reaction	417:424	arg1	Ag-ZrP					491:496	Ag-ZrP	491:496	Ag-ZrP	491:496	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	8	42	dep	films	1227:1231	arg1	embedded					1233:1240	embedded	1233:1240	embedded	1233:1240	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	1	43	theme	food	213:216	arg1	packaging					218:226	food packaging	213:226	food packaging	213:226	Polymers synthesized from green resources have many advantages in food packaging and hence their development is very important.					
36167104	5	44	theme	mechanical	844:853	arg1	strength					855:862	enhanced mechanical strength	835:862	enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite	835:903	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	4	45	theme	film	726:729	arg1	properties					691:700	the micro-morphology and mechanical properties	655:700	the micro-morphology and mechanical properties of the binary composite film	655:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	4	46	theme	composite	716:724	arg1	film					726:729	the binary composite film	705:729	the binary composite film	705:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	6	47	theme	films	1112:1116	arg1	stability					1085:1093	the thermal stability	1073:1093	the thermal stability of the composite films	1073:1116	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	4	48	theme	binary	709:714	arg1	film					726:729	the binary composite film	705:729	the binary composite film	705:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	5	49	theme	optimal	776:782	arg1	uniformity					784:793	optimal uniformity	776:793	optimal uniformity	776:793	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	5	49	theme	optimal	776:782	arg1	nanofibers					818:827	bead-free electrospun nanofibers	796:827	bead-free electrospun nanofibers	796:827	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	1	50	contain	have	189:192	arg2	advantages					199:208	many advantages	194:208	many advantages	194:208	Polymers synthesized from green resources have many advantages in food packaging and hence their development is very important.					
36167104	1	50	contain	have	189:192	arg1	Polymers					147:154	Polymers	147:154	Polymers synthesized from green resources	147:187	Polymers synthesized from green resources have many advantages in food packaging and hence their development is very important.					
36167104	3	51	theme	cross-linking	403:415	arg1	reaction					417:424	Steam-induced cross-linking reaction	389:424	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP)	389:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	6	52	theme	composite	1102:1110	arg1	films					1112:1116	the composite films	1098:1116	the composite films	1098:1116	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	9	53	from	prospects	1385:1393	arg1	field					1457:1461	the food packaging field	1438:1461	the food packaging field	1438:1461	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	5	54	with	uniformity	784:793	arg1	strength					855:862	enhanced mechanical strength	835:862	enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite	835:903	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	0	55	theme	food	48:51	arg1	packaging					53:61	food packaging	48:61	food packaging	48:61	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	5	56	theme	composite	754:762	arg1	film					764:767	The composite film	750:767	The composite film	750:767	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	0	57	dep	films	38:42	arg1	enhancement					134:144	antibacterial activity enhancement	111:144	antibacterial activity enhancement	111:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	57	dep	films	38:42	arg1	construction					71:82	Facile construction	64:82	Facile construction	64:82	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	57	dep	films	38:42	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	57	dep	films	38:42	arg1	property					97:104	hydrophobic property	85:104	hydrophobic property	85:104	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	8	58	theme	antibacterial	1270:1282	arg1	property					1284:1291	outstanding antibacterial property	1258:1291	outstanding antibacterial property	1258:1291	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	4	59	theme	ratio	646:650	arg1	effects					624:630	The effects	620:630	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film	620:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	0	60	theme	Facile	64:69	arg1	construction					71:82	Facile construction	64:82	Facile construction	64:82	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	0	60	theme	Facile	64:69	arg1	films					38:42	starch composite nanofibrous films	9:42	starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement	9:144	Emerging starch composite nanofibrous films for food packaging: Facile construction, hydrophobic property, and antibacterial activity enhancement.					
36167104	9	61	theme	potential	1375:1383	arg1	prospects					1385:1393	the potential prospects	1371:1393	the potential prospects of electrospun starch nanofibrous films in the food packaging field	1371:1461	This work demonstrated the potential prospects of electrospun starch nanofibrous films in the food packaging field.					
36167104	8	62	contain	had	1254:1256	arg2	property					1284:1291	outstanding antibacterial property	1258:1291	outstanding antibacterial property	1258:1291	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	8	62	contain	had	1254:1256	arg1	films					1227:1231	the starch/PVA films	1212:1231	the starch/PVA films embedded with Ag-ZrP	1212:1252	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	5	63	theme	starch/PVA	884:893	arg1	composite					895:903	the 60/40 (v/v) starch/PVA composite	868:903	the 60/40 (v/v) starch/PVA composite	868:903	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	3	64	theme	antibacterial	543:555	arg1	properties					557:566	the hydrophobic and antibacterial properties	523:566	the hydrophobic and antibacterial properties of the constructed nanofibrous films	523:603	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36167104	8	65	theme	Gram-positive	1324:1336	arg1	bacteria					1338:1345	both Gram-negative and Gram-positive bacteria	1301:1345	both Gram-negative and Gram-positive bacteria	1301:1345	Furthermore, the starch/PVA films embedded with Ag-ZrP had outstanding antibacterial property against both Gram-negative and Gram-positive bacteria.					
36167104	4	66	theme	micro-morphology	659:674	arg1	properties					691:700	the micro-morphology and mechanical properties	655:700	the micro-morphology and mechanical properties of the binary composite film	655:729	The effects of starch/PVA ratio on the micro-morphology and mechanical properties of the binary composite film were investigated.					
36167104	6	67	theme	thermal	1077:1083	arg1	stability					1085:1093	the thermal stability	1073:1093	the thermal stability of the composite films	1073:1116	Moreover, the crystallinity of PVA was reduced during the electrospinning process, whereas the introduction of PVA strengthened the hydrogen interactions and improved the thermal stability of the composite films.					
36167104	5	68	theme	60/40	872:876	arg1	composite					895:903	the 60/40 (v/v) starch/PVA composite	868:903	the 60/40 (v/v) starch/PVA composite	868:903	The composite film showed optimal uniformity, bead-free electrospun nanofibers, with enhanced mechanical strength for the 60/40 (v/v) starch/PVA composite.					
36167104	3	69	theme	Steam-induced	389:401	arg1	reaction					417:424	Steam-induced cross-linking reaction	389:424	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP)	389:497	Steam-induced cross-linking reaction with glutaraldehyde (GTA) and silver sodium zirconium phosphate (Ag-ZrP) was employed to improve the hydrophobic and antibacterial properties of the constructed nanofibrous films, respectively.					
36235668	6	0	theme	maternal	1657:1664	arg1	diet					1666:1669	maternal diet	1657:1669	maternal diet	1657:1669	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	1	1	theme	milk	401:404	arg1	composition					411:421	human milk (HM) composition	395:421	human milk (HM) composition	395:421	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	3	2	theme	food	890:893	arg1	insecurity					895:904	High food insecurity	885:904	High food insecurity indexes during the follow-up	885:933	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	3	theme	24-h	702:705	arg1	recalls					707:713	24-h recalls	702:713	24-h recalls	702:713	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	6	4	theme	Food	1637:1640	arg1	insecurity					1642:1651	Food insecurity	1637:1651	Food insecurity	1637:1651	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	3	5	dep	aß-coef	1144:1150	arg1	value					1162:1166	p value = 0.03	1160:1173	p value = 0.03	1160:1173	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	6	theme	HM	1581:1582	arg1	levels					1584:1589	lower HM levels	1575:1589	lower HM levels of lactose	1575:1600	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	3	7	dep	aß-coef	1098:1104	arg1	0.04					1124:1127	0.04	1124:1127	0.04	1124:1127	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	1	8	theme	Health	157:162	arg1	Organization					164:175	the World Health Organization	147:175	the World Health Organization (WHO)	147:181	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	2	9	from	TransmIssion	823:834	arg1	study					878:882	Central-Africa" (MITICA) study	853:882	Central-Africa" (MITICA) study	853:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	1	10	with	regions	460:466	arg1	insecurity					483:492	high food insecurity	473:492	high food insecurity	473:492	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	5	11	theme	many	1474:1477	arg1	levels					1464:1469	higher HM levels	1454:1469	higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001),	1454:1564	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	7	12	from	actions	1808:1814	arg1	security					1824:1831	food security	1819:1831	food security	1819:1831	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	3	13	theme	lower	1073:1077	arg1	levels					1079:1084	lower levels	1073:1084	lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001)	1073:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	14	dep	aß-coef	1603:1609	arg1	0.01					1630:1633	0.01	1630:1633	0.01	1630:1633	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	3	15	theme	=	1106:1106	arg1	aß-coef					1098:1104	aß-coef = −0.2	1098:1111	aß-coef = −0.2	1098:1111	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	15	theme	=	1106:1106	arg1	retinol					1089:1095	retinol	1089:1095	retinol (aß-coef = −0.2, p value = 0.04)	1089:1128	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	16	from	December	756:763	arg1	recalls					707:713	24-h recalls	702:713	24-h recalls	702:713	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	16	from	December	756:763	arg1	questionnaires					736:749	food consumption questionnaires	719:749	food consumption questionnaires	719:749	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	5	17	theme	=	1611:1611	arg1	aß-coef					1603:1609	aß-coef	1603:1609	aß-coef = −15.6	1603:1617	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	18	theme	dietary	369:375	arg1	factors					377:383	maternal dietary factors	360:383	maternal dietary factors	360:383	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	2	19	theme	undernourishment	508:523	arg1	status					525:530	The maternal undernourishment status	495:530	The maternal undernourishment status at delivery, maternal diet, and HM nutrients	495:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	7	20	theme	healthy	1952:1958	arg1	growth					1960:1965	healthy growth	1952:1965	healthy growth	1952:1965	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	3	21	theme	acids	1137:1141	arg1	levels					1079:1084	lower levels	1073:1084	lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001)	1073:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	22	theme	total	1511:1515	arg1	aß-coef					1530:1536	aß-coef = 5484.4	1530:1545	aß-coef = 5484.4	1530:1545	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	22	theme	total	1511:1515	arg1	acids					1523:1527	total amino acids	1511:1527	total amino acids (aß-coef = 5484.4, p value < 0.001)	1511:1563	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	22	theme	total	1511:1515	arg1	HMOs					1486:1489	the HMOs	1482:1489	the HMOs that were measured	1482:1508	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	3	23	theme	p	1160:1160	arg1	value					1162:1166	p value = 0.03	1160:1173	p value = 0.03	1160:1173	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	7	24	theme	effective	1839:1847	arg1	manner					1849:1854	an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth	1836:1965	an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth	1836:1965	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	4	25	theme	p	1361:1361	arg1	value					1363:1367	p value	1361:1367	p value	1361:1367	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	2	26	theme	MITICA	870:875	arg1	study					878:882	Central-Africa" (MITICA) study	853:882	Central-Africa" (MITICA) study	853:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	27	theme	=	1168:1168	arg1	value					1162:1166	p value = 0.03	1160:1173	p value = 0.03	1160:1173	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	28	theme	meat	1410:1413	arg1	consumption					1395:1405	the consumption	1391:1405	the consumption of meat, poultry, and fish	1391:1432	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	29	from	delivery	347:354	arg1	factors					377:383	maternal dietary factors	360:383	maternal dietary factors	360:383	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	1	29	from	delivery	347:354	arg1	status					337:342	the mother’s undernourishment status	307:342	the mother’s undernourishment status at delivery	307:354	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	1	30	theme	undernourishment	320:335	arg1	status					337:342	the mother’s undernourishment status	307:342	the mother’s undernourishment status at delivery	307:354	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	3	31	theme	lower	982:986	arg1	levels					988:993	lower levels	982:993	lower levels of many of the human milk oligosaccharides (HMOs) that were measured	982:1062	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	4	32	dep	=	1369:1369	arg1	3.3					1356:1358	3.3	1356:1358	3.3	1356:1358	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	2	33	from	microbiota	839:848	arg1	study					878:882	Central-Africa" (MITICA) study	853:882	Central-Africa" (MITICA) study	853:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	34	theme	"	867:867	arg1	study					878:882	Central-Africa" (MITICA) study	853:882	Central-Africa" (MITICA) study	853:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	35	theme	acids	1187:1191	arg1	levels					1079:1084	lower levels	1073:1084	lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001)	1073:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	36	theme	poultry	1416:1422	arg1	consumption					1395:1405	the consumption	1391:1405	the consumption of meat, poultry, and fish	1391:1432	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	0	37	theme	Food	0:3	arg1	Insecurity					5:14	Food Insecurity	0:14	Food Insecurity	0:14	Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa.					
36235668	6	38	theme	meaningful	1677:1686	arg1	effect					1688:1693	a meaningful effect	1675:1693	a meaningful effect	1675:1693	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	5	39	dep	aß-coef	1530:1536	arg1	<					1556:1556	p value < 0.001	1548:1562	p value < 0.001	1548:1562	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	2	40	from	delivery	535:542	arg1	status					525:530	The maternal undernourishment status	495:530	The maternal undernourishment status at delivery, maternal diet, and HM nutrients	495:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	7	41	theme	food	1819:1822	arg1	security					1824:1831	food security	1819:1831	food security	1819:1831	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	1	42	dep	Organization	164:175	arg1	WHO					178:180	WHO	178:180	WHO	178:180	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	6	43	theme	undernourishment	1752:1767	arg1	risk					1769:1772	an infant undernourishment risk	1742:1772	an infant undernourishment risk	1742:1772	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	6	43	theme	undernourishment	1752:1767	arg1	impact					1729:1734	a possible impact	1718:1734	a possible impact	1718:1734	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	2	44	theme	Mother-to-Infant	806:821	arg1	TransmIssion					823:834	the "Mother-to-Infant TransmIssion	801:834	the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study	801:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	0	45	theme	Human	44:48	arg1	Composition					55:65	Human Milk Composition	44:65	Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa	44:135	Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa.					
36235668	3	46	theme	oligosaccharides	1021:1036	arg1	many					998:1001	many	998:1001	many	998:1001	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	46	theme	oligosaccharides	1021:1036	arg1	HMOs					1039:1042	HMOs	1039:1042	HMOs	1039:1042	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	46	theme	oligosaccharides	1021:1036	arg1	oligosaccharides					1021:1036	the human milk oligosaccharides	1006:1036	the human milk oligosaccharides (HMOs) that were measured	1006:1062	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	47	theme	p	1548:1548	arg1	<					1556:1556	p value < 0.001	1548:1562	p value < 0.001	1548:1562	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	48	theme	life	452:455	arg1	months					442:447	the first 6 months	430:447	the first 6 months of life	430:455	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	5	49	theme	HM	1461:1462	arg1	levels					1464:1469	higher HM levels	1454:1469	higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001),	1454:1564	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	3	50	theme	human	1010:1014	arg1	HMOs					1039:1042	HMOs	1039:1042	HMOs	1039:1042	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	50	theme	human	1010:1014	arg1	oligosaccharides					1021:1036	the human milk oligosaccharides	1006:1036	the human milk oligosaccharides (HMOs) that were measured	1006:1062	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	0	51	from	Birth	113:117	arg1	Central-Africa					122:135	Central-Africa	122:135	Central-Africa	122:135	Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa.					
36235668	3	52	theme	p	1213:1213	arg1	<					1221:1221	p value < 0.001	1213:1227	p value < 0.001	1213:1227	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	53	theme	food	719:722	arg1	questionnaires					736:749	food consumption questionnaires	719:749	food consumption questionnaires	719:749	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	54	theme	consumption	724:734	arg1	questionnaires					736:749	food consumption questionnaires	719:749	food consumption questionnaires	719:749	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	5	55	theme	lactose	1594:1600	arg1	levels					1584:1589	lower HM levels	1575:1589	lower HM levels of lactose	1575:1600	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	56	theme	high	473:476	arg1	insecurity					483:492	high food insecurity	473:492	high food insecurity	473:492	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	6	57	theme	infant	1745:1750	arg1	risk					1769:1772	an infant undernourishment risk	1742:1772	an infant undernourishment risk	1742:1772	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	6	57	theme	infant	1745:1750	arg1	impact					1729:1734	a possible impact	1718:1734	a possible impact	1718:1734	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	2	58	theme	maternal	545:552	arg1	diet					554:557	maternal diet	545:557	maternal diet	545:557	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	59	theme	High	885:888	arg1	insecurity					895:904	High food insecurity	885:904	High food insecurity indexes during the follow-up	885:933	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	60	theme	HMOs	1486:1489	arg1	acids					1523:1527	total amino acids	1511:1527	total amino acids (aß-coef = 5484.4, p value < 0.001)	1511:1563	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	60	theme	HMOs	1486:1489	arg1	many					1474:1477	many	1474:1477	many	1474:1477	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	60	theme	HMOs	1486:1489	arg1	HMOs					1486:1489	the HMOs	1482:1489	the HMOs that were measured	1482:1508	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	61	theme	lower	1575:1579	arg1	levels					1584:1589	lower HM levels	1575:1589	lower HM levels of lactose	1575:1600	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	62	theme	World	151:155	arg1	Organization					164:175	the World Health Organization	147:175	the World Health Organization (WHO)	147:181	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	5	63	dep	=	1611:1611	arg1	−15.6					1613:1617	−15.6	1613:1617	−15.6	1613:1617	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	2	64	theme	HM	564:565	arg1	nutrients					567:575	HM nutrients	564:575	HM nutrients	564:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	65	theme	retinol	1089:1095	arg1	levels					1079:1084	lower levels	1073:1084	lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001)	1073:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	66	theme	insecurity	895:904	arg1	indexes					906:912	High food insecurity indexes	885:912	High food insecurity indexes during the follow-up	885:933	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	67	dep	associated	1438:1447	arg1	aß-coef					1603:1609	aß-coef	1603:1609	aß-coef = −15.6	1603:1617	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	1	68	theme	first	434:438	arg1	months					442:447	the first 6 months	430:447	the first 6 months of life	430:455	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	6	69	contain	had	1671:1673	arg1	insecurity					1642:1651	Food insecurity	1637:1651	Food insecurity	1637:1651	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	6	69	contain	had	1671:1673	arg1	diet					1666:1669	maternal diet	1657:1669	maternal diet	1657:1669	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	6	69	contain	had	1671:1673	arg2	effect					1688:1693	a meaningful effect	1675:1693	a meaningful effect	1675:1693	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	3	70	theme	fatty	1131:1135	arg1	aß-coef					1144:1150	aß-coef = −7.2	1144:1157	aß-coef = −7.2	1144:1157	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	70	theme	fatty	1131:1135	arg1	acids					1137:1141	fatty acids	1131:1141	fatty acids (aß-coef = −7.2, p value = 0.03)	1131:1174	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	4	71	theme	higher	1308:1313	arg1	levels					1315:1320	significantly higher levels	1294:1320	significantly higher levels of lactose	1294:1331	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	1	72	theme	maternal	360:367	arg1	factors					377:383	maternal dietary factors	360:383	maternal dietary factors	360:383	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	5	73	theme	=	1538:1538	arg1	aß-coef					1530:1536	aß-coef = 5484.4	1530:1545	aß-coef = 5484.4	1530:1545	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	73	theme	=	1538:1538	arg1	acids					1523:1527	total amino acids	1511:1527	total amino acids (aß-coef = 5484.4, p value < 0.001)	1511:1563	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	2	74	theme	born	629:632	arg1	infants					634:640	their 48 vaginally born infants	610:640	their 48 vaginally born infants	610:640	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	75	theme	=	1152:1152	arg1	aß-coef					1144:1150	aß-coef = −7.2	1144:1157	aß-coef = −7.2	1144:1157	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	75	theme	=	1152:1152	arg1	acids					1137:1141	fatty acids	1131:1141	fatty acids (aß-coef = −7.2, p value = 0.03)	1131:1174	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	76	theme	maternal	499:506	arg1	status					525:530	The maternal undernourishment status	495:530	The maternal undernourishment status at delivery, maternal diet, and HM nutrients	495:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	7	77	theme	infant	1932:1937	arg1	survival					1939:1946	infant survival	1932:1946	infant survival	1932:1946	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	4	78	theme	lactose	1325:1331	arg1	levels					1315:1320	significantly higher levels	1294:1320	significantly higher levels of lactose	1294:1331	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	1	79	theme	human	395:399	arg1	HM					407:408	HM	407:408	HM	407:408	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	1	79	theme	human	395:399	arg1	milk					401:404	human milk	395:404	human milk (HM) composition	395:421	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	5	80	theme	amino	1517:1521	arg1	aß-coef					1530:1536	aß-coef = 5484.4	1530:1545	aß-coef = 5484.4	1530:1545	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	80	theme	amino	1517:1521	arg1	acids					1523:1527	total amino acids	1511:1527	total amino acids (aß-coef = 5484.4, p value < 0.001)	1511:1563	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	80	theme	amino	1517:1521	arg1	HMOs					1486:1489	the HMOs	1482:1489	the HMOs that were measured	1482:1508	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	2	81	from	study	878:882	arg1	TransmIssion					823:834	the "Mother-to-Infant TransmIssion	801:834	the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study	801:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	82	theme	Central-Africa	853:866	arg1	study					878:882	Central-Africa" (MITICA) study	853:882	Central-Africa" (MITICA) study	853:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	6	83	theme	possible	1720:1727	arg1	risk					1769:1772	an infant undernourishment risk	1742:1772	an infant undernourishment risk	1742:1772	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	6	83	theme	possible	1720:1727	arg1	impact					1729:1734	a possible impact	1718:1734	a possible impact	1718:1734	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	7	84	dep	influence	1859:1867	arg1	improve					1924:1930	improve	1924:1930	improve infant survival and healthy growth	1924:1965	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	2	85	theme	microbiota	839:848	arg1	TransmIssion					823:834	the "Mother-to-Infant TransmIssion	801:834	the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study	801:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	86	dep	December	756:763	arg1	to					770:771	to	770:771	to	770:771	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	2	86	dep	December	756:763	arg1	June					773:776	June	773:776	June	773:776	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	4	87	from	households	1273:1282	arg1	women					1248:1252	women	1248:1252	women from food-insecure households	1248:1282	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	7	88	theme	HM	1896:1897	arg1	content					1885:1891	the nutritional content	1869:1891	the nutritional content of HM	1869:1897	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	7	89	theme	nutritional	1873:1883	arg1	content					1885:1891	the nutritional content	1869:1891	the nutritional content of HM	1869:1897	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	1	90	theme	food	478:481	arg1	insecurity					483:492	high food insecurity	473:492	high food insecurity	473:492	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	1	91	theme	mother’s	311:318	arg1	status					337:342	the mother’s undernourishment status	307:342	the mother’s undernourishment status at delivery	307:354	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	6	92	theme	HM	1698:1699	arg1	composition					1701:1711	HM composition	1698:1711	HM composition	1698:1711	Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk.					
36235668	3	93	dep	aß-coef	1194:1200	arg1	<					1221:1221	p value < 0.001	1213:1227	p value < 0.001	1213:1227	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	0	94	theme	Maternal	20:27	arg1	Diet					29:32	Maternal Diet	20:32	Maternal Diet	20:32	Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa.					
36235668	1	95	theme	first	257:261	arg1	months					265:270	the first 6 months	253:270	the first 6 months of life	253:278	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	3	96	theme	many	998:1001	arg1	levels					988:993	lower levels	982:993	lower levels of many of the human milk oligosaccharides (HMOs) that were measured	982:1062	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	97	from	diet	554:557	arg1	status					525:530	The maternal undernourishment status	495:530	The maternal undernourishment status at delivery, maternal diet, and HM nutrients	495:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	98	theme	amino	1181:1185	arg1	aß-coef					1194:1200	aß-coef = −2121.0	1194:1210	aß-coef = −2121.0	1194:1210	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	98	theme	amino	1181:1185	arg1	acids					1187:1191	amino acids	1181:1191	amino acids (aß-coef = −2121.0, p value < 0.001)	1181:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	99	theme	TransmIssion	823:834	arg1	context					790:796	the context	786:796	the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study	786:882	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	0	100	theme	Milk	50:53	arg1	Composition					55:65	Human Milk Composition	44:65	Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa	44:135	Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant's Birth and 6 Months after Birth in Central-Africa.					
36235668	1	101	theme	life	275:278	arg1	months					265:270	the first 6 months	253:270	the first 6 months of life	253:278	Although the World Health Organization (WHO) and UNICEF recommend that infants should be exclusively breastfed for the first 6 months of life, evidence is scarce on how the mother’s undernourishment status at delivery and maternal dietary factors influence human milk (HM) composition during the first 6 months of life in regions with high food insecurity.					
36235668	3	102	theme	milk	1016:1019	arg1	HMOs					1039:1042	HMOs	1039:1042	HMOs	1039:1042	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	102	theme	milk	1016:1019	arg1	oligosaccharides					1021:1036	the human milk oligosaccharides	1006:1036	the human milk oligosaccharides (HMOs) that were measured	1006:1062	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	2	103	from	nutrients	567:575	arg1	status					525:530	The maternal undernourishment status	495:530	The maternal undernourishment status at delivery, maternal diet, and HM nutrients	495:575	The maternal undernourishment status at delivery, maternal diet, and HM nutrients were assessed among 46 women and their 48 vaginally born infants in Bangui at 1, 4, 11, 18, and 25 weeks after birth through 24-h recalls and food consumption questionnaires from December 2017 to June 2019 in the context of the "Mother-to-Infant TransmIssion of microbiota in Central-Africa" (MITICA) study.					
36235668	3	104	theme	=	1202:1202	arg1	aß-coef					1194:1200	aß-coef = −2121.0	1194:1210	aß-coef = −2121.0	1194:1210	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	3	104	theme	=	1202:1202	arg1	acids					1187:1191	amino acids	1181:1191	amino acids (aß-coef = −2121.0, p value < 0.001)	1181:1228	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	105	theme	higher	1454:1459	arg1	levels					1464:1469	higher HM levels	1454:1469	higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001),	1454:1564	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	5	106	theme	value	1550:1554	arg1	<					1556:1556	p value < 0.001	1548:1562	p value < 0.001	1548:1562	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
36235668	7	107	theme	consistent	1797:1806	arg1	actions					1808:1814	consistent actions	1797:1814	consistent actions on food security	1797:1831	Our results plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.					
36235668	4	108	theme	food-insecure	1259:1271	arg1	households					1273:1282	food-insecure households	1259:1282	food-insecure households	1259:1282	On the contrary, women from food-insecure households displayed significantly higher levels of lactose in their HM (aß-coef = 3.3, p value = 0.02).					
36235668	3	109	theme	value	1215:1219	arg1	<					1221:1221	p value < 0.001	1213:1227	p value < 0.001	1213:1227	High food insecurity indexes during the follow-up were significantly associated with them having lower levels of many of the human milk oligosaccharides (HMOs) that were measured and with lower levels of retinol (aß-coef = −0.2, p value = 0.04), fatty acids (aß-coef = −7.2, p value = 0.03), and amino acids (aß-coef = −2121.0, p value < 0.001).					
36235668	5	110	theme	fish	1429:1432	arg1	consumption					1395:1405	the consumption	1391:1405	the consumption of meat, poultry, and fish	1391:1432	In parallel, the consumption of meat, poultry, and fish was associated with higher HM levels of many of the HMOs that were measured, total amino acids (aß-coef = 5484.4, p value < 0.001), and with lower HM levels of lactose (aß-coef = −15.6, p value = 0.01).					
35384131	2	0	theme	hydrogels	367:375	arg1	benefits					355:362	the benefits	351:362	the benefits of hydrogels in accelerating wound healing	351:405	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	5	1	theme	hydrogel	955:962	arg1	dressings					964:972	hydrogel dressings	955:972	hydrogel dressings	955:972	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	4	2	from	variations	822:831	arg1	architecture					845:856	collagen architecture	836:856	collagen architecture	836:856	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	4	2	from	variations	822:831	arg1	alignment					862:870	alignment	862:870	alignment	862:870	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	3	3	theme	splinted	521:528	arg1	model					547:551	a splinted excisional wound model	519:551	a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings	519:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	1	4	theme	wound	269:273	arg1	healing					275:281	wound healing	269:281	wound healing outcomes	269:290	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	0	5	theme	available	113:121	arg1	dressings					132:140	commercially available collagen dressings	100:140	commercially available collagen dressings	100:140	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	5	6	theme	resulting	1039:1047	arg1	architecture					1049:1060	resulting architecture	1039:1060	resulting architecture of healed scars	1039:1076	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	7	7	theme	novel	1377:1381	arg1	insights					1383:1390	novel insights	1377:1390	novel insights	1377:1390	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	1	8	theme	healing	275:281	arg1	outcomes					283:290	wound healing outcomes	269:290	wound healing outcomes	269:290	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	7	9	theme	Further	1255:1261	arg1	understanding					1263:1275	Further understanding	1255:1275	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds	1255:1363	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	4	10	from	response	895:902	arg1	architecture					845:856	collagen architecture	836:856	collagen architecture	836:856	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	4	10	from	response	895:902	arg1	alignment					862:870	alignment	862:870	alignment	862:870	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	5	11	theme	cellular	1016:1023	arg1	response					1025:1032	cellular response	1016:1032	cellular response	1016:1032	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	3	12	theme	human-like	572:581	arg1	healing					589:595	human-like wound healing	572:595	human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings	572:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	4	13	theme	histopathologic	757:771	arg1	analysis					773:780	histologic and histopathologic analysis	742:780	analysis	773:780	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	3	14	with	wounds	617:622	arg1	dressings					663:671	three different collagen hydrogel dressings	629:671	three different collagen hydrogel dressings	629:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	6	15	theme	pullulan-collagen	1097:1113	arg1	dressing					1124:1131	our pullulan-collagen hydrogel dressing	1093:1131	our pullulan-collagen hydrogel dressing	1093:1131	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	6	16	theme	shorter	1230:1236	arg1	fibres					1247:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	1	17	theme	ideal	193:197	arg1	physio-mimetic					200:213	an ideal, physio-mimetic	190:213	physio-mimetic	200:213	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	0	18	theme	collagen	123:130	arg1	dressings					132:140	commercially available collagen dressings	100:140	commercially available collagen dressings	100:140	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	6	19	with	tissue	1179:1184	arg1	fibres					1247:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	0	20	theme	Pullulan-Collagen	0:16	arg1	dressing					33:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	6	21	theme	wound	1145:1149	arg1	closure					1151:1157	wound closure	1145:1157	wound closure	1145:1157	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	0	22	theme	hydrogel	18:25	arg1	dressing					33:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	7	23	theme	hydrogel	1284:1291	arg1	properties					1293:1302	hydrogel properties	1284:1302	hydrogel properties	1284:1302	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	6	24	theme	dense	1196:1200	arg1	fibres					1247:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	2	25	theme	hydrogel	460:467	arg1	compositions					478:489	different hydrogel material compositions	450:489	different hydrogel material compositions	450:489	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	4	26	theme	tissue	888:893	arg1	response					895:902	the tissue response	884:902	the tissue response	884:902	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	6	27	theme	aligned	1217:1223	arg1	fibres					1247:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	7	28	theme	properties	1433:1442	arg1	insights					1383:1390	novel insights	1377:1390	novel insights	1377:1390	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	7	28	theme	properties	1433:1442	arg1	optimization					1404:1415	further optimization	1396:1415	further optimization of the material properties of wound dressings	1396:1461	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	2	29	theme	wound	393:397	arg1	healing					399:405	wound healing	393:405	wound healing	393:405	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	2	30	theme	different	450:458	arg1	compositions					478:489	different hydrogel material compositions	450:489	different hydrogel material compositions	450:489	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	1	31	theme	cutaneous	298:306	arg1	injury					308:313	cutaneous injury	298:313	cutaneous injury	298:313	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	5	32	theme	material	932:939	arg1	properties					941:950	the material properties	928:950	the material properties of hydrogel dressings	928:972	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	2	33	theme	most	322:325	arg1	studies					327:333	most studies	322:333	most studies	322:333	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	7	34	theme	dressings	1453:1461	arg1	properties					1433:1442	the material properties	1420:1442	the material properties of wound dressings	1420:1461	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	1	35	theme	native	218:223	arg1	ECM					247:249	ECM	247:249	ECM	247:249	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	1	35	theme	native	218:223	arg1	matrix					239:244	native extracellular matrix	218:244	native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury	218:313	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	0	36	theme	wound	27:31	arg1	dressing					33:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing	0:40	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	4	37	theme	explanted	789:797	arg1	tissues					804:810	the explanted scar tissues	785:810	the explanted scar tissues	785:810	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	1	38	theme	extracellular	225:237	arg1	ECM					247:249	ECM	247:249	ECM	247:249	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	1	38	theme	extracellular	225:237	arg1	matrix					239:244	native extracellular matrix	218:244	native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury	218:313	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	0	39	theme	dermal	51:56	arg1	remodelling					58:68	dermal remodelling	51:68	dermal remodelling	51:68	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	4	40	theme	histologic	742:751	arg1	analysis					773:780	histologic and histopathologic analysis	742:780	analysis	773:780	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	1	41	theme	matrix	239:244	arg1	physio-mimetic					200:213	an ideal, physio-mimetic	190:213	physio-mimetic	200:213	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	5	42	theme	healed	1065:1070	arg1	scars					1072:1076	healed scars	1065:1076	healed scars	1065:1076	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	2	43	theme	minimal	418:424	arg1	data					426:429	minimal data	418:429	minimal data directly comparing different hydrogel material compositions	418:489	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	7	44	theme	further	1396:1402	arg1	optimization					1404:1415	further optimization	1396:1415	further optimization of the material properties of wound dressings	1396:1461	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	5	45	theme	scars	1072:1076	arg1	architecture					1049:1060	resulting architecture	1039:1060	resulting architecture of healed scars	1039:1076	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	5	45	theme	scars	1072:1076	arg1	time					1010:1013	healing time	1002:1013	healing time	1002:1013	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	5	45	theme	scars	1072:1076	arg1	response					1025:1032	cellular response	1016:1032	cellular response	1016:1032	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	7	46	theme	wound	1447:1451	arg1	dressings					1453:1461	wound dressings	1447:1461	wound dressings	1447:1461	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	4	47	theme	scar	799:802	arg1	tissues					804:810	the explanted scar tissues	785:810	the explanted scar tissues	785:810	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	3	48	used	utilized	510:517	arg2	we					507:508	we	507:508	we	507:508	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	5	49	theme	healing	1002:1008	arg1	time					1010:1013	healing time	1002:1013	healing time	1002:1013	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	6	50	theme	collagen	1238:1245	arg1	fibres					1247:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	less dense, more randomly aligned, and shorter collagen fibres	1191:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	3	51	theme	treated	609:615	arg1	wounds					617:622	treated wounds	609:622	treated wounds	609:622	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	1	52	theme	Biological	143:152	arg1	scaffolds					154:162	Biological scaffolds	143:162	Biological scaffolds such as hydrogels	143:180	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	1	52	theme	Biological	143:152	arg1	hydrogels					172:180	hydrogels	172:180	hydrogels	172:180	Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury.					
35384131	4	53	from	analysis	773:780	arg1	tissues					804:810	the explanted scar tissues	785:810	the explanted scar tissues	785:810	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	7	54	theme	resulting	1327:1335	arg1	architecture					1342:1353	the healing and resulting scar architecture	1311:1353	architecture	1342:1353	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	4	55	theme	collagen	836:843	arg1	architecture					845:856	collagen architecture	836:856	collagen architecture	836:856	We assessed the feasibility of applying each dressing and performed histologic and histopathologic analysis on the explanted scar tissues to assess variations in collagen architecture and alignment, as well as the tissue response.					
35384131	3	56	theme	collagen	645:652	arg1	dressings					663:671	three different collagen hydrogel dressings	629:671	three different collagen hydrogel dressings	629:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	5	57	theme	dressings	964:972	arg1	properties					941:950	the material properties	928:950	the material properties of hydrogel dressings	928:972	Our data indicate that the material properties of hydrogel dressings can significantly influence healing time, cellular response, and resulting architecture of healed scars.					
35384131	3	58	theme	wound	583:587	arg1	healing					589:595	human-like wound healing	572:595	human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings	572:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	7	59	theme	wounds	1358:1363	arg1	architecture					1342:1353	the healing and resulting scar architecture	1311:1353	architecture	1342:1353	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	7	59	theme	wounds	1358:1363	arg1	healing					1315:1321	the healing and resulting scar architecture	1311:1353	healing	1315:1321	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	3	60	theme	hydrogel	654:661	arg1	dressings					663:671	three different collagen hydrogel dressings	629:671	three different collagen hydrogel dressings	629:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	3	61	theme	wound	541:545	arg1	model					547:551	a splinted excisional wound model	519:551	a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings	519:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	7	62	theme	scar	1337:1340	arg1	architecture					1342:1353	the healing and resulting scar architecture	1311:1353	architecture	1342:1353	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	6	63	theme	healed	1172:1177	arg1	tissue					1179:1184	healed tissue	1172:1184	healed tissue with less dense, more randomly aligned, and shorter collagen fibres	1172:1252	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	6	64	theme	hydrogel	1115:1122	arg1	dressing					1124:1131	our pullulan-collagen hydrogel dressing	1093:1131	our pullulan-collagen hydrogel dressing	1093:1131	Specifically, our pullulan-collagen hydrogel dressing accelerated wound closure and promoted healed tissue with less dense, more randomly aligned, and shorter collagen fibres.					
35384131	3	65	theme	excisional	530:539	arg1	model					547:551	a splinted excisional wound model	519:551	a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings	519:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	3	66	from	healing	589:595	arg1	wounds					617:622	treated wounds	609:622	treated wounds	609:622	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	3	66	from	healing	589:595	arg1	mice					600:603	mice	600:603	mice	600:603	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	0	67	theme	wound	74:78	arg1	healing					80:86	wound healing	74:86	wound healing	74:86	Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.					
35384131	7	68	theme	material	1424:1431	arg1	properties					1433:1442	the material properties	1420:1442	the material properties of wound dressings	1420:1461	Further understanding of how hydrogel properties affect the healing and resulting scar architecture of wounds may lead to novel insights and further optimization of the material properties of wound dressings.					
35384131	3	69	theme	different	635:643	arg1	dressings					663:671	three different collagen hydrogel dressings	629:671	three different collagen hydrogel dressings	629:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35384131	2	70	theme	material	469:476	arg1	compositions					478:489	different hydrogel material compositions	450:489	different hydrogel material compositions	450:489	While most studies have focused on the benefits of hydrogels in accelerating wound healing, there are minimal data directly comparing different hydrogel material compositions.					
35384131	3	71	with	mice	600:603	arg1	dressings					663:671	three different collagen hydrogel dressings	629:671	three different collagen hydrogel dressings	629:671	In this study, we utilized a splinted excisional wound model that recapitulates human-like wound healing in mice and treated wounds with three different collagen hydrogel dressings.					
35349304	5	0	theme	defined	815:821	arg1	"					834:834	Spatially defined agar "plugs"	805:834	Spatially defined agar "plugs" of interest	805:846	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	9	1	theme	augmented	1673:1681	arg1	metabolism					1683:1692	augmented metabolism	1673:1692	augmented metabolism	1673:1692	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	3	2	theme	metaproteomic	540:552	arg1	studies					554:560	spatiotemporal metaproteomic studies	525:560	spatiotemporal metaproteomic studies of root-associated microbiomes	525:591	How microbiomes change with respect to space and time across plant roots remains poorly understood, and methodologies that facilitate spatiotemporal metaproteomic studies of root-associated microbiomes are yet to be realized.					
35349304	4	3	from	systems	753:759	arg1	embedded					722:729	embedded	722:729	embedded	722:729	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	0	4	theme	Root-Associated	76:90	arg1	Metaproteomics					92:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	4	5	used	used	783:786	arg2	systems					753:759	agar-plate culture systems	734:759	agar-plate culture systems	734:759	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	8	6	theme	spatial	1363:1369	arg1	resolution					1371:1380	The spatial resolution	1359:1380	The spatial resolution of these measurements	1359:1402	The spatial resolution of these measurements provides evidence that microbiome composition and expression changes across the plant root interface.					
35349304	5	7	used	used	963:966	arg2	metaproteomics					937:950	metaproteomics	937:950	metaproteomics	937:950	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	7	8	dep	locations	1290:1298	arg1	tip					1317:1319	root tip	1312:1319	root tip	1312:1319	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	8	dep	locations	1290:1298	arg1	region					1328:1333	a region	1326:1333	a region	1326:1333	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	8	dep	locations	1290:1298	arg1	locations					1290:1298	three distinct locations	1275:1298	three distinct locations (root base, root tip, and a region distant from the root)	1275:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	8	dep	locations	1290:1298	arg1	base					1306:1309	root base	1301:1309	root base	1301:1309	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	5	9	theme	community	992:1000	arg1	composition					1002:1012	microbial community composition	982:1012	microbial community composition	982:1012	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	10	10	theme	extraction	1793:1802	arg1	method					1804:1809	a novel peptide extraction method	1777:1809	a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements	1777:1921	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	7	11	theme	time	1245:1248	arg1	points					1250:1255	two time points	1241:1255	two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root)	1241:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	11	theme	time	1245:1248	arg1	h					1268:1268	24 and 48 h	1258:1268	24 and 48 h	1258:1268	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	9	12	theme	proteomes	1548:1556	arg1	Interrogation					1506:1518	Interrogation	1506:1518	Interrogation of the individual microbial proteomes	1506:1556	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	5	13	theme	novel	896:900	arg1	method					921:926	a novel peptide extraction method	894:926	a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function	894:1025	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	7	14	theme	root	1301:1304	arg1	locations					1290:1298	three distinct locations	1275:1298	three distinct locations (root base, root tip, and a region distant from the root)	1275:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	14	theme	root	1301:1304	arg1	base					1306:1309	root base	1301:1309	root base	1301:1309	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	3	15	theme	microbiomes	581:591	arg1	studies					554:560	spatiotemporal metaproteomic studies	525:560	spatiotemporal metaproteomic studies of root-associated microbiomes	525:591	How microbiomes change with respect to space and time across plant roots remains poorly understood, and methodologies that facilitate spatiotemporal metaproteomic studies of root-associated microbiomes are yet to be realized.					
35349304	4	16	from	embedded	722:729	arg1	systems					753:759	agar-plate culture systems	734:759	agar-plate culture systems	734:759	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	1	17	theme	vital	188:192	arg1	role					194:197	a vital role	186:197	a vital role	186:197	Plant-microbe interactions in the rhizosphere play a vital role in plant health and productivity.					
35349304	0	18	theme	Agar-Plate	116:125	arg1	System					127:132	an Agar-Plate System	113:132	an Agar-Plate System	113:132	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	1	19	from	interactions	149:160	arg1	rhizosphere					169:179	the rhizosphere	165:179	the rhizosphere	165:179	Plant-microbe interactions in the rhizosphere play a vital role in plant health and productivity.					
35349304	10	20	theme	peptide	1785:1791	arg1	method					1804:1809	a novel peptide extraction method	1777:1809	a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements	1777:1921	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	7	21	from	root	1352:1355	arg1	distant					1335:1341	distant	1335:1341	distant	1335:1341	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	4	22	theme	plant	710:714	arg1	roots					716:720	plant roots	710:720	plant roots embedded in agar-plate culture systems, which have long been used to study plants	710:802	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	5	23	theme	interest	839:846	arg1	"					834:834	Spatially defined agar "plugs"	805:834	Spatially defined agar "plugs" of interest	805:846	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	5	24	theme	agar	823:826	arg1	"					834:834	Spatially defined agar "plugs"	805:834	Spatially defined agar "plugs" of interest	805:846	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	10	25	theme	agar-plate	1830:1839	arg1	systems					1849:1855	plant agar-plate culture systems	1824:1855	plant agar-plate culture systems	1824:1855	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	10	26	theme	culture	1841:1847	arg1	systems					1849:1855	plant agar-plate culture systems	1824:1855	plant agar-plate culture systems	1824:1855	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	5	27	theme	extraction	910:919	arg1	method					921:926	a novel peptide extraction method	894:926	a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function	894:1025	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	10	28	theme	novel	1779:1783	arg1	method					1804:1809	a novel peptide extraction method	1777:1809	a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements	1777:1921	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	8	29	theme	root	1490:1493	arg1	interface					1495:1503	the plant root interface	1480:1503	the plant root interface	1480:1503	The spatial resolution of these measurements provides evidence that microbiome composition and expression changes across the plant root interface.					
35349304	9	30	theme	individual	1527:1536	arg1	proteomes					1548:1556	the individual microbial proteomes	1523:1556	the individual microbial proteomes	1523:1556	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	3	31	theme	plant	452:456	arg1	roots					458:462	plant roots	452:462	plant roots	452:462	How microbiomes change with respect to space and time across plant roots remains poorly understood, and methodologies that facilitate spatiotemporal metaproteomic studies of root-associated microbiomes are yet to be realized.					
35349304	0	32	theme	Experimental	18:29	arg1	Approach					31:38	an Experimental Approach	15:38	an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics	15:105	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	9	33	theme	abundant	1736:1743	arg1	member					1745:1750	the most abundant member	1727:1750	the most abundant member	1727:1750	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	9	34	with	associations	1615:1626	arg1	root					1643:1646	the plant root	1633:1646	the plant root	1633:1646	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	5	35	theme	microbial	982:990	arg1	composition					1002:1012	microbial community composition	982:1012	microbial community composition	982:1012	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	4	36	theme	metaproteome	678:689	arg1	measurements					691:702	spatially resolved metaproteome measurements	659:702	spatially resolved metaproteome measurements	659:702	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	9	37	theme	behavioral	1604:1613	arg1	associations					1615:1626	their behavioral associations	1598:1626	their behavioral associations	1598:1626	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	9	38	theme	member	1745:1750	arg1	predominance					1711:1722	predominance	1711:1722	predominance of the most abundant member	1711:1750	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	2	39	theme	surrounding	325:335	arg1	environment					337:347	their surrounding environment	319:347	their surrounding environment	319:347	The composition and function of root-associated microbiomes is strongly influenced by their surrounding environment, which is often customized by their host.					
35349304	4	40	theme	resolved	669:676	arg1	measurements					691:702	spatially resolved metaproteome measurements	659:702	spatially resolved metaproteome measurements	659:702	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	3	41	theme	spatiotemporal	525:538	arg1	studies					554:560	spatiotemporal metaproteomic studies	525:560	spatiotemporal metaproteomic studies of root-associated microbiomes	525:591	How microbiomes change with respect to space and time across plant roots remains poorly understood, and methodologies that facilitate spatiotemporal metaproteomic studies of root-associated microbiomes are yet to be realized.					
35349304	10	42	theme	proteomic	1900:1908	arg1	measurements					1910:1921	(meta)proteomic measurements	1894:1921	(meta)proteomic measurements	1894:1921	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	1	43	theme	plant	202:206	arg1	health					208:213	plant health	202:213	plant health	202:213	Plant-microbe interactions in the rhizosphere play a vital role in plant health and productivity.					
35349304	0	44	theme	Approach	31:38	arg1	Development					0:10	Development	0:10	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics	0:105	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	5	45	theme	plugs	829:833	arg1	"					834:834	Spatially defined agar "plugs"	805:834	Spatially defined agar "plugs" of interest	805:846	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	9	46	theme	plant	1637:1641	arg1	root					1643:1646	the plant root	1633:1646	the plant root	1633:1646	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	6	47	theme	root	1121:1124	arg1	system					1126:1131	a Populus root system	1111:1131	a Populus root system	1111:1131	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	5	48	theme	prior	928:932	arg1	method					921:926	a novel peptide extraction method	894:926	a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function	894:1025	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	10	49	theme	meta	1895:1898	arg1	measurements					1910:1921	(meta)proteomic measurements	1894:1921	(meta)proteomic measurements	1894:1921	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	6	50	theme	agar	1149:1152	arg1	plate					1154:1158	an agar plate	1146:1158	an agar plate	1146:1158	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	6	51	theme	3-week-old	1167:1176	arg1	plant					1198:1202	a 3-week-old Populus trichocarpa plant	1165:1202	a 3-week-old Populus trichocarpa plant	1165:1202	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	6	52	theme	Populus	1113:1119	arg1	system					1126:1131	a Populus root system	1111:1131	a Populus root system	1111:1131	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	8	53	theme	plant	1484:1488	arg1	interface					1495:1503	the plant root interface	1480:1503	the plant root interface	1480:1503	The spatial resolution of these measurements provides evidence that microbiome composition and expression changes across the plant root interface.					
35349304	8	54	theme	measurements	1391:1402	arg1	resolution					1371:1380	The spatial resolution	1359:1380	The spatial resolution of these measurements	1359:1402	The spatial resolution of these measurements provides evidence that microbiome composition and expression changes across the plant root interface.					
35349304	7	55	theme	distant	1335:1341	arg1	locations					1290:1298	three distinct locations	1275:1298	three distinct locations (root base, root tip, and a region distant from the root)	1275:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	55	theme	distant	1335:1341	arg1	base					1306:1309	root base	1301:1309	root base	1301:1309	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	1	56	theme	Plant-microbe	135:147	arg1	interactions					149:160	Plant-microbe interactions	135:160	Plant-microbe interactions in the rhizosphere	135:179	Plant-microbe interactions in the rhizosphere play a vital role in plant health and productivity.					
35349304	10	57	theme	plant	1824:1828	arg1	systems					1849:1855	plant agar-plate culture systems	1824:1855	plant agar-plate culture systems	1824:1855	This study demonstrated a novel peptide extraction method for studying plant agar-plate culture systems, which was previously unsuitable for (meta)proteomic measurements.					
35349304	7	58	theme	distinct	1281:1288	arg1	tip					1317:1319	root tip	1312:1319	root tip	1312:1319	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	58	theme	distinct	1281:1288	arg1	region					1328:1333	a region	1326:1333	a region	1326:1333	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	58	theme	distinct	1281:1288	arg1	locations					1290:1298	three distinct locations	1275:1298	three distinct locations (root base, root tip, and a region distant from the root)	1275:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	58	theme	distinct	1281:1288	arg1	base					1306:1309	root base	1301:1309	root base	1301:1309	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	4	59	theme	embedded	722:729	arg1	roots					716:720	plant roots	710:720	plant roots embedded in agar-plate culture systems, which have long been used to study plants	710:802	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	9	60	theme	microbial	1538:1546	arg1	proteomes					1548:1556	the individual microbial proteomes	1523:1556	the individual microbial proteomes	1523:1556	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	6	61	theme	trichocarpa	1186:1196	arg1	plant					1198:1202	a 3-week-old Populus trichocarpa plant	1165:1202	a 3-week-old Populus trichocarpa plant	1165:1202	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	6	62	theme	10-member	1074:1082	arg1	proof-of-principle					1033:1050	a proof-of-principle	1031:1050	a proof-of-principle	1031:1050	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	6	62	theme	10-member	1074:1082	arg1	community					1084:1092	a previously studied 10-member community	1053:1092	a previously studied 10-member community constructed from a Populus root system	1053:1131	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	9	63	theme	functional	1567:1576	arg1	profiles					1578:1585	functional profiles	1567:1585	functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member	1567:1750	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	2	64	theme	microbiomes	281:291	arg1	function					253:260	function	253:260	function	253:260	The composition and function of root-associated microbiomes is strongly influenced by their surrounding environment, which is often customized by their host.					
35349304	2	64	theme	microbiomes	281:291	arg1	composition					237:247	composition	237:247	composition	237:247	The composition and function of root-associated microbiomes is strongly influenced by their surrounding environment, which is often customized by their host.					
35349304	4	65	theme	agar-plate	734:743	arg1	systems					753:759	agar-plate culture systems	734:759	agar-plate culture systems	734:759	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	6	66	theme	studied	1066:1072	arg1	proof-of-principle					1033:1050	a proof-of-principle	1031:1050	a proof-of-principle	1031:1050	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	6	66	theme	studied	1066:1072	arg1	community					1084:1092	a previously studied 10-member community	1053:1092	a previously studied 10-member community constructed from a Populus root system	1053:1131	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	0	67	theme	Plant	70:74	arg1	Metaproteomics					92:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	7	68	theme	root	1312:1315	arg1	tip					1317:1319	root tip	1312:1319	root tip	1312:1319	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	7	68	theme	root	1312:1315	arg1	locations					1290:1298	three distinct locations	1275:1298	three distinct locations (root base, root tip, and a region distant from the root)	1275:1356	Metaproteomics was performed across two time points (24 and 48 h) for three distinct locations (root base, root tip, and a region distant from the root).					
35349304	2	69	theme	root-associated	265:279	arg1	microbiomes					281:291	root-associated microbiomes	265:291	root-associated microbiomes	265:291	The composition and function of root-associated microbiomes is strongly influenced by their surrounding environment, which is often customized by their host.					
35349304	2	70	dep	composition	237:247	arg1	The					233:235	The	233:235	The	233:235	The composition and function of root-associated microbiomes is strongly influenced by their surrounding environment, which is often customized by their host.					
35349304	4	71	theme	culture	745:751	arg1	systems					753:759	agar-plate culture systems	734:759	agar-plate culture systems	734:759	Here, we developed a method that provides spatially resolved metaproteome measurements along plant roots embedded in agar-plate culture systems, which have long been used to study plants.					
35349304	5	72	theme	peptide	902:908	arg1	method					921:926	a novel peptide extraction method	894:926	a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function	894:1025	Spatially defined agar "plugs" of interest were excised and subsequently processed using a novel peptide extraction method prior to metaproteomics, which was used to infer both microbial community composition and function.					
35349304	0	73	theme	Resolved	61:68	arg1	Metaproteomics					92:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Spatially Resolved Plant Root-Associated Metaproteomics	51:105	Development of an Experimental Approach to Achieve Spatially Resolved Plant Root-Associated Metaproteomics Using an Agar-Plate System.					
35349304	6	74	theme	Populus	1178:1184	arg1	plant					1198:1202	a 3-week-old Populus trichocarpa plant	1165:1202	a 3-week-old Populus trichocarpa plant	1165:1202	As a proof-of-principle, a previously studied 10-member community constructed from a Populus root system was grown in an agar plate with a 3-week-old Populus trichocarpa plant.					
35349304	8	75	theme	microbiome	1427:1436	arg1	composition					1438:1448	microbiome composition	1427:1448	microbiome composition	1427:1448	The spatial resolution of these measurements provides evidence that microbiome composition and expression changes across the plant root interface.					
35349304	9	76	theme	related	1587:1593	arg1	profiles					1578:1585	functional profiles	1567:1585	functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member	1567:1750	Interrogation of the individual microbial proteomes revealed functional profiles related to their behavioral associations with the plant root, in which chemotaxis and augmented metabolism likely supported predominance of the most abundant member.					
35349304	3	77	theme	root-associated	565:579	arg1	microbiomes					581:591	root-associated microbiomes	565:591	root-associated microbiomes	565:591	How microbiomes change with respect to space and time across plant roots remains poorly understood, and methodologies that facilitate spatiotemporal metaproteomic studies of root-associated microbiomes are yet to be realized.					
36448086	15	0	theme	engineer	1803:1810	arg1	tissues					1824:1830	tissue engineer replacement tissues	1796:1830	tissue engineer replacement tissues	1796:1830	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	14	1	from	prevalence	1592:1601	arg1	surface					1637:1643	the superior surface	1624:1643	the superior surface of the tissue	1624:1657	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	7	2	theme	Frequency	831:839	arg1	tests					847:851	Frequency sweep tests	831:851	Frequency sweep tests	831:851	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	5	3	theme	surface	634:640	arg1	layers					642:647	the surface layers	630:647	the surface layers	630:647	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	6	4	theme	porcine	780:786	arg1	menisci					788:794	porcine menisci	780:794	porcine menisci (medial and lateral, n = 10 each)	780:828	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	10	5	theme	shear	1139:1143	arg1	modulus					1145:1151	the lowest shear modulus	1128:1151	the lowest shear modulus	1128:1151	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	8	6	theme	Mechanical	910:919	arg1	behavior					921:928	Mechanical behavior	910:928	Mechanical behavior of regions	910:939	Mechanical behavior of regions was described by a generalized Maxwell model.					
36448086	12	7	theme	surface	1378:1384	arg1	layers					1386:1391	the surface layers	1374:1391	the surface layers	1374:1391	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	11	8	theme	tissue	1284:1289	arg1	regions					1291:1297	all tissue regions	1280:1297	all tissue regions	1280:1297	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	5	9	theme	shear	610:614	arg1	properties					616:625	the dynamic shear properties	598:625	the dynamic shear properties of the surface layers	598:647	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	2	10	theme	fibrocartilaginous	302:319	arg1	core					321:324	the meniscus fibrocartilaginous core	289:324	the meniscus fibrocartilaginous core	289:324	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	1	11	theme	shear	170:174	arg1	loads					176:180	excessive shear loads	160:180	excessive shear loads	160:180	Damage to the meniscus has been associated with excessive shear loads.					
36448086	3	12	with	inhomogeneous	365:377	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	12	with	inhomogeneous	365:377	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	6	13	dep	menisci	788:794	arg1	n = 10					817:822	n = 10	817:822	n = 10 each	817:827	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	12	14	theme	tissue	1314:1319	arg1	composition					1321:1331	Inhomogeneous tissue composition	1300:1331	Inhomogeneous tissue composition	1300:1331	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	14	15	theme	femoral	1555:1561	arg1	layer					1563:1567	the femoral layer	1551:1567	the femoral layer	1551:1567	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	10	16	contain	had	1124:1126	arg1	surface					1116:1122	The femoral surface	1104:1122	The femoral surface	1104:1122	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	10	16	contain	had	1124:1126	arg2	modulus					1145:1151	the lowest shear modulus	1128:1151	the lowest shear modulus	1128:1151	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	5	17	theme	empirical	660:668	arg1	relations					670:678	empirical relations	660:678	empirical relations with their composition	660:701	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	13	18	theme	shear	1479:1483	arg1	properties					1485:1494	shear properties	1479:1494	shear properties in all regions	1479:1509	Water content negatively correlated with shear properties in all regions.					
36448086	14	19	theme	shear	1531:1535	arg1	properties					1537:1546	The lower measured shear properties	1512:1546	The lower measured shear properties in the femoral layer	1512:1567	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	15	20	theme	tissue	1693:1698	arg1	behavior					1677:1684	The heterogenous behavior	1660:1684	The heterogenous behavior of the tissue in shear	1660:1707	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	14	21	theme	tears	1615:1619	arg1	prevalence					1592:1601	the higher prevalence	1581:1601	the higher prevalence of meniscal tears on the superior surface of the tissue	1581:1657	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	2	22	theme	previous	230:237	arg1	studies					239:245	previous studies	230:245	previous studies	230:245	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	11	23	theme	Maxwell	1217:1223	arg1	model					1225:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	15	24	contain	has	1754:1756	arg1	behavior					1677:1684	The heterogenous behavior	1660:1684	The heterogenous behavior of the tissue in shear	1660:1707	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	15	24	contain	has	1754:1756	arg2	implications					1768:1779	important implications	1758:1779	important implications for efforts to tissue engineer replacement tissues	1758:1830	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	11	25	theme	3-relaxation	1198:1209	arg1	model					1225:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	10	26	theme	tibial	1180:1185	arg1	regions					1187:1193	tibial regions	1180:1193	tibial regions	1180:1193	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	0	27	theme	tissue	80:85	arg1	core					87:90	tissue core	80:90	tissue core	80:90	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	14	28	theme	higher	1585:1590	arg1	prevalence					1592:1601	the higher prevalence	1581:1601	the higher prevalence of meniscal tears on the superior surface of the tissue	1581:1657	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	8	29	theme	generalized	960:970	arg1	model					980:984	a generalized Maxwell model	958:984	a generalized Maxwell model	958:984	Mechanical behavior of regions was described by a generalized Maxwell model.					
36448086	7	30	theme	phase	892:896	arg1	shifts					898:903	phase shifts	892:903	phase shifts (δ)	892:907	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	7	30	theme	phase	892:896	arg1	δ					906:906	δ	906:906	δ	906:906	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	12	31	from	content	1363:1369	arg1	layers					1386:1391	the surface layers	1374:1391	the surface layers	1374:1391	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	15	32	theme	important	1758:1766	arg1	implications					1768:1779	important implications	1758:1779	important implications for efforts to tissue engineer replacement tissues	1758:1830	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	3	33	theme	surface	440:446	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	33	theme	surface	440:446	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	7	34	theme	G	884:884	arg1	modulus					875:881	complex shear modulus	861:881	complex shear modulus (G*)	861:886	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	7	34	theme	G	884:884	arg1	*					885:885	G*	884:885	G*	884:885	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	15	35	theme	meniscus	1731:1738	arg1	pathology					1740:1748	meniscus pathology	1731:1748	meniscus pathology	1731:1748	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	0	36	theme	dynamic	17:23	arg1	properties					31:40	dynamic shear properties	17:40	dynamic shear properties of the meniscus	17:56	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	15	37	from	behavior	1677:1684	arg1	shear					1703:1707	shear	1703:1707	shear	1703:1707	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	4	38	theme	surface	539:545	arg1	layers					547:552	the surface layers	535:552	the surface layers	535:552	To date, little is known about the shear behavior of the surface layers.					
36448086	0	39	theme	properties	31:40	arg1	Heterogeneity					0:12	Heterogeneity	0:12	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.	0:110	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	10	40	theme	femoral	1108:1114	arg1	surface					1116:1122	The femoral surface	1104:1122	The femoral surface	1104:1122	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	3	41	theme	cartilaginous	397:409	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	41	theme	cartilaginous	397:409	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	6	42	dep	n = 10	817:822	arg1	each					824:827	each	824:827	each	824:827	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	9	43	theme	tissue	1070:1075	arg1	regions					1077:1083	the tissue regions	1066:1083	the tissue regions	1066:1083	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	9	44	with	Correlations	987:998	arg1	glycosaminoglycans					1036:1053	glycosaminoglycans	1036:1053	glycosaminoglycans	1036:1053	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	9	44	with	Correlations	987:998	arg1	water					1026:1030	water	1026:1030	water	1026:1030	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	12	45	theme	tissue	1425:1430	arg1	core					1432:1435	tissue core	1425:1435	tissue core	1425:1435	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	4	46	theme	shear	517:521	arg1	behavior					523:530	the shear behavior	513:530	the shear behavior of the surface layers	513:552	To date, little is known about the shear behavior of the surface layers.					
36448086	10	47	theme	lowest	1132:1137	arg1	modulus					1145:1151	the lowest shear modulus	1128:1151	the lowest shear modulus	1128:1151	The femoral surface had the lowest shear modulus, when compared to core and tibial regions.					
36448086	15	48	theme	replacement	1812:1822	arg1	tissues					1824:1830	tissue engineer replacement tissues	1796:1830	tissue engineer replacement tissues	1796:1830	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	14	49	from	properties	1537:1546	arg1	layer					1563:1567	the femoral layer	1551:1567	the femoral layer	1551:1567	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	7	50	theme	shear	869:873	arg1	modulus					875:881	complex shear modulus	861:881	complex shear modulus (G*)	861:886	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	7	50	theme	shear	869:873	arg1	*					885:885	G*	884:885	G*	884:885	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	0	51	dep	Heterogeneity	0:12	arg1	comparison					61:70	A comparison	59:70	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.	0:110	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	15	52	theme	tissue	1796:1801	arg1	tissues					1824:1830	tissue engineer replacement tissues	1796:1830	tissue engineer replacement tissues	1796:1830	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	6	53	theme	menisci	788:794	arg1	core					772:775	core	772:775	core of porcine menisci (medial and lateral, n = 10 each)	772:828	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	6	53	theme	menisci	788:794	arg1	layers					761:766	tibial and femoral surface layers	734:766	tibial and femoral surface layers	734:766	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	7	54	theme	sweep	841:845	arg1	tests					847:851	Frequency sweep tests	831:851	Frequency sweep tests	831:851	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	13	55	from	properties	1485:1494	arg1	regions					1503:1509	all regions	1499:1509	all regions	1499:1509	Water content negatively correlated with shear properties in all regions.					
36448086	2	56	theme	shear	269:273	arg1	properties					275:284	the shear properties	265:284	the shear properties of the meniscus fibrocartilaginous core	265:324	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	8	57	theme	regions	933:939	arg1	behavior					921:928	Mechanical behavior	910:928	Mechanical behavior of regions	910:939	Mechanical behavior of regions was described by a generalized Maxwell model.					
36448086	12	58	theme	water	1357:1361	arg1	content					1363:1369	water content	1357:1369	water content in the surface layers	1357:1391	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	5	59	theme	dynamic	602:608	arg1	properties					616:625	the dynamic shear properties	598:625	the dynamic shear properties of the surface layers	598:647	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	2	60	theme	core	321:324	arg1	properties					275:284	the shear properties	265:284	the shear properties of the meniscus fibrocartilaginous core	265:324	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	1	61	theme	excessive	160:168	arg1	loads					176:180	excessive shear loads	160:180	excessive shear loads	160:180	Damage to the meniscus has been associated with excessive shear loads.					
36448086	6	62	theme	surface	753:759	arg1	layers					761:766	tibial and femoral surface layers	734:766	tibial and femoral surface layers	734:766	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	2	63	theme	meniscus	293:300	arg1	core					321:324	the meniscus fibrocartilaginous core	289:324	the meniscus fibrocartilaginous core	289:324	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	6	64	theme	tibial	734:739	arg1	layers					761:766	tibial and femoral surface layers	734:766	tibial and femoral surface layers	734:766	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	14	65	theme	tissue	1652:1657	arg1	surface					1637:1643	the superior surface	1624:1643	the superior surface of the tissue	1624:1657	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	11	66	theme	regions	1291:1297	arg1	behavior					1268:1275	the shear behavior	1258:1275	the shear behavior of all tissue regions	1258:1297	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	5	67	theme	layers	642:647	arg1	properties					616:625	the dynamic shear properties	598:625	the dynamic shear properties of the surface layers	598:647	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	2	68	theme	meniscus	204:211	arg1	pathophysiology					213:227	meniscus pathophysiology	204:227	meniscus pathophysiology	204:227	Aimed at elucidating meniscus pathophysiology, previous studies have investigated the shear properties of the meniscus fibrocartilaginous core.					
36448086	12	69	theme	Inhomogeneous	1300:1312	arg1	composition					1321:1331	Inhomogeneous tissue composition	1300:1331	Inhomogeneous tissue composition	1300:1331	Inhomogeneous tissue composition was also observed, with water content in the surface layers being higher when compared with tissue core.					
36448086	14	70	theme	superior	1628:1635	arg1	surface					1637:1643	the superior surface	1624:1643	the superior surface of the tissue	1624:1657	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	15	71	theme	heterogenous	1664:1675	arg1	behavior					1677:1684	The heterogenous behavior	1660:1684	The heterogenous behavior of the tissue in shear	1660:1707	The heterogenous behavior of the tissue in shear provides insight into meniscus pathology and has important implications for efforts to tissue engineer replacement tissues.					
36448086	14	72	theme	measured	1522:1529	arg1	properties					1537:1546	The lower measured shear properties	1512:1546	The lower measured shear properties in the femoral layer	1512:1567	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	14	73	theme	meniscal	1606:1613	arg1	tears					1615:1619	meniscal tears	1606:1619	meniscal tears	1606:1619	The lower measured shear properties in the femoral layer may explain the higher prevalence of meniscal tears on the superior surface of the tissue.					
36448086	8	74	theme	Maxwell	972:978	arg1	model					980:984	a generalized Maxwell model	958:984	a generalized Maxwell model	958:984	Mechanical behavior of regions was described by a generalized Maxwell model.					
36448086	5	75	theme	study	577:581	arg1	objective					559:567	The objective	555:567	The objective of this study	555:581	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	11	76	theme	times	1211:1215	arg1	model					1225:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model	1196:1229	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	9	77	theme	shear	1008:1012	arg1	moduli					1014:1019	shear moduli	1008:1019	shear moduli	1008:1019	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	0	78	theme	surface	96:102	arg1	layers					104:109	surface layers	96:109	surface layers	96:109	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	11	79	theme	shear	1262:1266	arg1	behavior					1268:1275	the shear behavior	1258:1275	the shear behavior of all tissue regions	1258:1297	A 3-relaxation times Maxwell model satisfactorily interpreted the shear behavior of all tissue regions.					
36448086	3	80	theme	external	388:395	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	80	theme	external	388:395	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	81	theme	femoral	432:438	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	81	theme	femoral	432:438	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	0	82	theme	shear	25:29	arg1	properties					31:40	dynamic shear properties	17:40	dynamic shear properties of the meniscus	17:56	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	4	83	theme	layers	547:552	arg1	behavior					523:530	the shear behavior	513:530	the shear behavior of the surface layers	513:552	To date, little is known about the shear behavior of the surface layers.					
36448086	3	84	theme	tissue	469:474	arg1	core					476:479	the tissue core	465:479	the tissue core	465:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	0	85	gly	Heterogeneity	0:12	arg1	properties					31:40	dynamic shear properties	17:40	dynamic shear properties of the meniscus	17:56	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	5	86	with	relations	670:678	arg1	composition					691:701	their composition	685:701	their composition	685:701	The objective of this study was to measure the dynamic shear properties of the surface layers and derive empirical relations with their composition.					
36448086	3	87	theme	tibial	421:426	arg1	envelope					411:418	an external cartilaginous envelope	385:418	an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core	385:479	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	3	87	theme	tibial	421:426	arg1	layers					448:453	tibial and femoral surface layers	421:453	tibial and femoral surface layers	421:453	However, the meniscus is structurally inhomogeneous, with an external cartilaginous envelope (tibial and femoral surface layers) wrapping the tissue core.					
36448086	6	88	theme	femoral	745:751	arg1	layers					761:766	tibial and femoral surface layers	734:766	tibial and femoral surface layers	734:766	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	0	89	theme	meniscus	49:56	arg1	properties					31:40	dynamic shear properties	17:40	dynamic shear properties of the meniscus	17:56	Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers.					
36448086	13	90	theme	Water	1438:1442	arg1	content					1444:1450	Water content	1438:1450	Water content	1438:1450	Water content negatively correlated with shear properties in all regions.					
36448086	9	91	dep	water	1026:1030	arg1	content					1055:1061	content	1055:1061	content	1055:1061	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	9	92	theme	regions	1077:1083	arg1	glycosaminoglycans					1036:1053	glycosaminoglycans	1036:1053	glycosaminoglycans	1036:1053	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	9	92	theme	regions	1077:1083	arg1	water					1026:1030	water	1026:1030	water	1026:1030	Correlations between shear moduli with water and glycosaminoglycans content of the tissue regions were investigated.					
36448086	6	93	theme	lateral	808:814	arg1	n = 10					817:822	n = 10	817:822	n = 10 each	817:827	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
36448086	7	94	theme	complex	861:867	arg1	modulus					875:881	complex shear modulus	861:881	complex shear modulus (G*)	861:886	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	7	94	theme	complex	861:867	arg1	*					885:885	G*	884:885	G*	884:885	Frequency sweep tests yielded complex shear modulus (G*) and phase shifts (δ).					
36448086	6	95	theme	medial	797:802	arg1	n = 10					817:822	n = 10	817:822	n = 10 each	817:827	Specimens were harvested from tibial and femoral surface layers and core of porcine menisci (medial and lateral, n = 10 each).					
35661803	6	0	theme	adhering	932:939	arg1	BNC-TS-C					1035:1042	BNC-TS-C	1035:1042	BNC-TS-C	1035:1042	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	0	theme	adhering	932:939	arg1	Spheres					1026:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres	932:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days	932:1056	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	0	1	theme	modified	34:41	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	7	2	with	platforms	1136:1144	arg1	microenvironment					1160:1175	distinct microenvironment	1151:1175	distinct microenvironment	1151:1175	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	7	3	theme	spheroid	1127:1134	arg1	platforms					1136:1144	translucid spheroid platforms	1116:1144	translucid spheroid platforms with distinct microenvironment	1116:1175	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	7	3	theme	spheroid	1127:1134	arg1	RESULTS					1059:1065	RESULTS	1059:1065	RESULTS BNC-TS-H and BNC-TS-C platforms	1059:1097	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	11	4	theme	distinct	1602:1609	arg1	platforms					1627:1635	distinct microstructured platforms	1602:1635	distinct microstructured platforms of BNC-TS-H and BNC-TS-C	1602:1660	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	8	5	theme	chemical	1209:1216	arg1	characterizations					1231:1247	The chemical and physical characterizations	1205:1247	The chemical and physical characterizations	1205:1247	The chemical and physical characterizations confirmed the platforms composition as BNC.					
35661803	1	6	used	used	167:170	arg2	nanocellulose					138:150	BACKGROUND Bacterial nanocellulose	117:150	BACKGROUND Bacterial nanocellulose (BNC)	117:156	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	6	used	used	167:170	arg2	support					180:186	cell support	175:186	cell support in numerous tissue engineering studies	175:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	6	used	used	167:170	arg2	BNC					153:155	BNC	153:155	BNC	153:155	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	11	7	theme	BNC-TS-C	1653:1660	arg1	platforms					1627:1635	distinct microstructured platforms	1602:1635	distinct microstructured platforms of BNC-TS-H and BNC-TS-C	1602:1660	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	4	8	from	conditions	675:684	arg1	medium					697:702	minimal medium	689:702	minimal medium	689:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	8	9	theme	physical	1222:1229	arg1	characterizations					1231:1247	The chemical and physical characterizations	1205:1247	The chemical and physical characterizations	1205:1247	The chemical and physical characterizations confirmed the platforms composition as BNC.					
35661803	2	10	dep	fact	266:269	arg1	allows					285:290	allows	285:290	allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture	285:388	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	11	11	theme	BNC-TS-H	1640:1647	arg1	platforms					1627:1635	distinct microstructured platforms	1602:1635	distinct microstructured platforms of BNC-TS-H and BNC-TS-C	1602:1660	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	1	12	theme	tissue	200:205	arg1	studies					219:225	numerous tissue engineering studies	191:225	numerous tissue engineering studies	191:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	7	13	theme	BNC-TS-C	1080:1087	arg1	platforms					1089:1097	BNC-TS-C platforms	1080:1097	BNC-TS-C platforms	1080:1097	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	14	14	theme	GENERAL	1851:1857	arg1	SIGNIFICANCE					1859:1870	GENERAL SIGNIFICANCE	1851:1870	GENERAL SIGNIFICANCE	1851:1870	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	8	15	theme	platforms	1263:1271	arg1	composition					1273:1283	the platforms composition	1259:1283	the platforms composition	1259:1283	The chemical and physical characterizations confirmed the platforms composition as BNC.					
35661803	10	16	from	phenotype	1509:1517	arg1	72 h					1522:1525	72 h	1522:1525	72 h of culture	1522:1536	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	4	17	theme	dynamic	659:665	arg1	conditions					675:684	dynamic culture conditions	659:684	dynamic culture conditions in minimal medium	659:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	6	18	theme	Translucid	955:964	arg1	BNC-TS-H					979:986	BNC-TS-H	979:986	BNC-TS-H	979:986	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	18	theme	Translucid	955:964	arg1	Spheres					970:976	the Hollow Translucid BNC Spheres	944:976	the Hollow Translucid BNC Spheres (BNC-TS-H)	944:987	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	9	19	theme	internal	1306:1313	arg1	relevant					1360:1367	relevant	1360:1367	relevant	1360:1367	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	9	19	theme	internal	1306:1313	arg1	microenvironments					1315:1331	The produced internal microenvironments	1293:1331	The produced internal microenvironments in spherical platforms	1293:1354	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	5	20	theme	chemical	709:716	arg1	composition					718:728	chemical composition	709:728	chemical composition	709:728	The chemical composition and physical properties of the platforms were evaluated.					
35661803	14	21	dep	produced	1883:1890	arg1	SIGNIFICANCE					1859:1870	GENERAL SIGNIFICANCE	1851:1870	GENERAL SIGNIFICANCE	1851:1870	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	0	22	theme	hollow	78:83	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	1	23	from	support	180:186	arg1	studies					219:225	numerous tissue engineering studies	191:225	numerous tissue engineering studies	191:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	5	24	dep	composition	718:728	arg1	The					705:707	The	705:707	The	705:707	The chemical composition and physical properties of the platforms were evaluated.					
35661803	13	25	theme	tissue	1831:1836	arg1	engineering					1838:1848	tissue engineering	1831:1848	tissue engineering	1831:1848	This behavior suggests several applications in tissue engineering.					
35661803	0	26	theme	compartimentalized	89:106	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	1	27	theme	cell	175:178	arg1	support					180:186	cell support	175:186	cell support in numerous tissue engineering studies	175:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	27	theme	cell	175:178	arg1	nanocellulose					138:150	BACKGROUND Bacterial nanocellulose	117:150	BACKGROUND Bacterial nanocellulose (BNC)	117:156	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	6	28	theme	Translucid	1011:1020	arg1	BNC-TS-C					1035:1042	BNC-TS-C	1035:1042	BNC-TS-C	1035:1042	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	28	theme	Translucid	1011:1020	arg1	Spheres					1026:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres	932:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days	932:1056	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	11	29	theme	minimal	1578:1584	arg1	medium					1586:1591	minimal medium	1578:1591	minimal medium	1578:1591	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	9	30	theme	cell	1388:1391	arg1	fate					1393:1396	tumor cell fate	1382:1396	tumor cell fate	1382:1396	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	3	31	dep	oxygen	493:498	arg1	transportation					514:527	transportation	514:527	transportation	514:527	Its structure and interconnected pores lead to animal cells adhesion and proliferation, also allowing oxygen and nutrients transportation.					
35661803	2	32	theme	cell	377:380	arg1	culture					382:388	3D cell culture	374:388	3D cell culture	374:388	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	0	33	theme	Melanoma	0:7	arg1	growth					9:14	Melanoma growth	0:14	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.	0:115	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	13	34	from	applications	1815:1826	arg1	engineering					1838:1848	tissue engineering	1831:1848	tissue engineering	1831:1848	This behavior suggests several applications in tissue engineering.					
35661803	1	35	theme	BACKGROUND	117:126	arg1	support					180:186	cell support	175:186	cell support in numerous tissue engineering studies	175:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	35	theme	BACKGROUND	117:126	arg1	BNC					153:155	BNC	153:155	BNC	153:155	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	35	theme	BACKGROUND	117:126	arg1	nanocellulose					138:150	BACKGROUND Bacterial nanocellulose	117:150	BACKGROUND Bacterial nanocellulose (BNC)	117:156	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	12	36	theme	cell-cell	1744:1752	arg1	interactions					1770:1781	distinct cell-cell and cell-matrix interactions	1735:1781	distinct cell-cell and cell-matrix interactions	1735:1781	The platforms microstructure resulted in microenvironments that enabled distinct cell-cell and cell-matrix interactions.					
35661803	4	37	theme	new	553:555	arg1	methodology					557:567	a new methodology	551:567	a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium	551:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	14	38	theme	cell	1963:1966	arg1	culture					1968:1974	3D cell culture	1960:1974	3D cell culture	1960:1974	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	11	39	from	fermentation	1562:1573	arg1	medium					1586:1591	minimal medium	1578:1591	minimal medium	1578:1591	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	12	40	theme	cell-matrix	1758:1768	arg1	interactions					1770:1781	distinct cell-cell and cell-matrix interactions	1735:1781	distinct cell-cell and cell-matrix interactions	1735:1781	The platforms microstructure resulted in microenvironments that enabled distinct cell-cell and cell-matrix interactions.					
35661803	10	41	dep	typical	1492:1498	arg1	tumorous					1500:1507	tumorous	1500:1507	tumorous	1500:1507	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	7	42	theme	dynamic	1183:1189	arg1	fermentation					1191:1202	dynamic fermentation	1183:1202	dynamic fermentation	1183:1202	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	2	43	theme	ideal	343:347	arg1	material					349:356	an ideal material	340:356	an ideal material	340:356	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	0	44	theme	bacterial	54:62	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	14	45	theme	distinct	1929:1936	arg1	microenvironments					1938:1954	distinct microenvironments	1929:1954	distinct microenvironments for 3D cell culture	1929:1974	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	7	46	dep	RESULTS	1059:1065	arg1	BNC-TS-H					1067:1074	BNC-TS-H	1067:1074	BNC-TS-H	1067:1074	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	7	46	dep	RESULTS	1059:1065	arg1	platforms					1089:1097	BNC-TS-C platforms	1080:1097	BNC-TS-C platforms	1080:1097	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	10	47	theme	culture	1420:1426	arg1	12 h					1412:1415	the first 12 h	1402:1415	the first 12 h of culture	1402:1426	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	14	48	theme	BNC	1903:1905	arg1	platforms					1914:1922	translucid BNC sphere platforms	1892:1922	translucid BNC sphere platforms	1892:1922	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	0	49	theme	nanocellulose	64:76	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	9	50	from	microenvironments	1315:1331	arg1	platforms					1346:1354	spherical platforms	1336:1354	spherical platforms	1336:1354	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	4	51	theme	spherical	580:588	arg1	platforms					590:598	spherical platforms	580:598	spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium	580:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	7	52	theme	translucid	1116:1125	arg1	platforms					1136:1144	translucid spheroid platforms	1116:1144	translucid spheroid platforms with distinct microenvironment	1116:1175	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	7	52	theme	translucid	1116:1125	arg1	RESULTS					1059:1065	RESULTS	1059:1065	RESULTS BNC-TS-H and BNC-TS-C platforms	1059:1097	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	11	53	theme	microstructured	1611:1625	arg1	platforms					1627:1635	distinct microstructured platforms	1602:1635	distinct microstructured platforms of BNC-TS-H and BNC-TS-C	1602:1660	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	4	54	theme	minimal	689:695	arg1	medium					697:702	minimal medium	689:702	minimal medium	689:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	4	55	theme	culture	667:673	arg1	conditions					675:684	dynamic culture conditions	659:684	dynamic culture conditions in minimal medium	659:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	2	56	theme	required	310:317	arg1	microenvironment					319:334	a required microenvironment	308:334	a required microenvironment for an ideal material, which supports 3D cell culture	308:388	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	1	57	theme	numerous	191:198	arg1	studies					219:225	numerous tissue engineering studies	191:225	numerous tissue engineering studies	191:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	6	58	theme	melanoma	799:806	arg1	cells					808:812	human melanoma cells	793:812	human melanoma cells (SK-MEL-28)	793:824	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	58	theme	melanoma	799:806	arg1	SK-MEL-28					815:823	SK-MEL-28	815:823	SK-MEL-28	815:823	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	59	theme	human	793:797	arg1	cells					808:812	human melanoma cells	793:812	human melanoma cells (SK-MEL-28)	793:824	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	59	theme	human	793:797	arg1	SK-MEL-28					815:823	SK-MEL-28	815:823	SK-MEL-28	815:823	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	1	60	theme	engineering	207:217	arg1	studies					219:225	numerous tissue engineering studies	191:225	numerous tissue engineering studies	191:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	5	61	theme	physical	734:741	arg1	properties					743:752	physical properties	734:752	physical properties	734:752	The chemical composition and physical properties of the platforms were evaluated.					
35661803	12	62	theme	platforms	1667:1675	arg1	microstructure					1677:1690	The platforms microstructure	1663:1690	The platforms microstructure	1663:1690	The platforms microstructure resulted in microenvironments that enabled distinct cell-cell and cell-matrix interactions.					
35661803	9	63	theme	produced	1297:1304	arg1	relevant					1360:1367	relevant	1360:1367	relevant	1360:1367	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	9	63	theme	produced	1297:1304	arg1	microenvironments					1315:1331	The produced internal microenvironments	1293:1331	The produced internal microenvironments in spherical platforms	1293:1354	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	6	64	theme	Hollow	948:953	arg1	BNC-TS-H					979:986	BNC-TS-H	979:986	BNC-TS-H	979:986	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	64	theme	Hollow	948:953	arg1	Spheres					970:976	the Hollow Translucid BNC Spheres	944:976	the Hollow Translucid BNC Spheres (BNC-TS-H)	944:987	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	11	65	theme	dynamic	1554:1560	arg1	fermentation					1562:1573	The dynamic fermentation	1550:1573	The dynamic fermentation in minimal medium	1550:1591	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	10	66	theme	nanocellulose	1451:1463	arg1	microfibers					1465:1475	nanocellulose microfibers	1451:1475	nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture	1451:1536	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	9	67	theme	spherical	1336:1344	arg1	platforms					1346:1354	spherical platforms	1336:1354	spherical platforms	1336:1354	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	6	68	theme	BNC	1022:1024	arg1	BNC-TS-C					1035:1042	BNC-TS-C	1035:1042	BNC-TS-C	1035:1042	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	68	theme	BNC	1022:1024	arg1	Spheres					1026:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres	932:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days	932:1056	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	0	69	from	growth	9:14	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	11	70	dep	CONCLUSION	1539:1548	arg1	produced					1593:1600	produced	1593:1600	produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C	1593:1660	CONCLUSION The dynamic fermentation in minimal medium produced distinct microstructured platforms of BNC-TS-H and BNC-TS-C.					
35661803	4	71	dep	METHODS	530:536	arg1	developed					541:549	developed	541:549	developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium	541:702	METHODS We developed a new methodology to produce spherical platforms synthesized by Komagataebacter hansenii (ATCC 23769) under dynamic culture conditions in minimal medium.					
35661803	6	72	theme	Compartmentalized	993:1009	arg1	BNC-TS-C					1035:1042	BNC-TS-C	1035:1042	BNC-TS-C	1035:1042	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	72	theme	Compartmentalized	993:1009	arg1	Spheres					1026:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres	932:1032	adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days	932:1056	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	10	73	theme	typical	1492:1498	arg1	phenotype					1509:1517	their typical tumorous phenotype	1486:1517	their typical tumorous phenotype in 72 h of culture	1486:1536	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	5	74	theme	platforms	761:769	arg1	composition					718:728	chemical composition	709:728	chemical composition	709:728	The chemical composition and physical properties of the platforms were evaluated.					
35661803	5	74	theme	platforms	761:769	arg1	properties					743:752	physical properties	734:752	physical properties	734:752	The chemical composition and physical properties of the platforms were evaluated.					
35661803	9	75	theme	tumor	1382:1386	arg1	fate					1393:1396	tumor cell fate	1382:1396	tumor cell fate	1382:1396	The produced internal microenvironments in spherical platforms are relevant to determine tumor cell fate.					
35661803	13	76	theme	several	1807:1813	arg1	applications					1815:1826	several applications	1807:1826	several applications in tissue engineering	1807:1848	This behavior suggests several applications in tissue engineering.					
35661803	6	77	dep	3 days	1051:1056	arg1	up					1045:1046	up	1045:1046	up	1045:1046	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	3	78	theme	animal	438:443	arg1	cells					445:449	animal cells	438:449	animal cells	438:449	Its structure and interconnected pores lead to animal cells adhesion and proliferation, also allowing oxygen and nutrients transportation.					
35661803	2	79	theme	3D	374:375	arg1	culture					382:388	3D cell culture	374:388	3D cell culture	374:388	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	1	80	theme	Bacterial	128:136	arg1	support					180:186	cell support	175:186	cell support in numerous tissue engineering studies	175:225	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	80	theme	Bacterial	128:136	arg1	BNC					153:155	BNC	153:155	BNC	153:155	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	1	80	theme	Bacterial	128:136	arg1	nanocellulose					138:150	BACKGROUND Bacterial nanocellulose	117:150	BACKGROUND Bacterial nanocellulose (BNC)	117:156	BACKGROUND Bacterial nanocellulose (BNC) has been used as cell support in numerous tissue engineering studies.					
35661803	12	81	theme	distinct	1735:1742	arg1	interactions					1770:1781	distinct cell-cell and cell-matrix interactions	1735:1781	distinct cell-cell and cell-matrix interactions	1735:1781	The platforms microstructure resulted in microenvironments that enabled distinct cell-cell and cell-matrix interactions.					
35661803	0	82	theme	translucid	43:52	arg1	spheres					108:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres	19:114	Melanoma growth in non-chemically modified translucid bacterial nanocellulose hollow and compartimentalized spheres.					
35661803	14	83	theme	3D	1960:1961	arg1	culture					1968:1974	3D cell culture	1960:1974	3D cell culture	1960:1974	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	6	84	theme	metabolic	880:888	arg1	activity					890:897	metabolic activity	880:897	metabolic activity	880:897	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	3	85	theme	interconnected	409:422	arg1	pores					424:428	interconnected pores	409:428	interconnected pores	409:428	Its structure and interconnected pores lead to animal cells adhesion and proliferation, also allowing oxygen and nutrients transportation.					
35661803	10	86	theme	first	1406:1410	arg1	12 h					1412:1415	the first 12 h	1402:1415	the first 12 h of culture	1402:1426	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	7	87	theme	distinct	1151:1158	arg1	microenvironment					1160:1175	distinct microenvironment	1151:1175	distinct microenvironment	1151:1175	RESULTS BNC-TS-H and BNC-TS-C platforms were produced as translucid spheroid platforms with distinct microenvironment under dynamic fermentation.					
35661803	6	88	theme	BNC	966:968	arg1	BNC-TS-H					979:986	BNC-TS-H	979:986	BNC-TS-H	979:986	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	6	88	theme	BNC	966:968	arg1	Spheres					970:976	the Hollow Translucid BNC Spheres	944:976	the Hollow Translucid BNC Spheres (BNC-TS-H)	944:987	Then, human melanoma cells (SK-MEL-28) were encapsulated into the platforms and evaluated by metabolic activity, morphology and their ability on adhering to the Hollow Translucid BNC Spheres (BNC-TS-H) and Compartmentalized Translucid BNC Spheres (BNC-TS-C) up to 3 days.					
35661803	10	89	theme	culture	1530:1536	arg1	72 h					1522:1525	72 h	1522:1525	72 h of culture	1522:1536	In the first 12 h of culture, cells could adhere to nanocellulose microfibers assuming their typical tumorous phenotype in 72 h of culture.					
35661803	2	90	theme	microenvironment	319:334	arg1	creation					296:303	the creation	292:303	the creation of a required microenvironment for an ideal material, which supports 3D cell culture	292:388	Its use can be explained based on the fact its structure allows the creation of a required microenvironment for an ideal material, which supports 3D cell culture.					
35661803	14	91	theme	sphere	1907:1912	arg1	platforms					1914:1922	translucid BNC sphere platforms	1892:1922	translucid BNC sphere platforms	1892:1922	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
35661803	14	92	theme	translucid	1892:1901	arg1	platforms					1914:1922	translucid BNC sphere platforms	1892:1922	translucid BNC sphere platforms	1892:1922	GENERAL SIGNIFICANCE The method produced translucid BNC sphere platforms with distinct microenvironments for 3D cell culture.					
36094958	6	0	from	study	907:911	arg1	data					891:894	data	891:894	data from a new study	891:911	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	6	1	theme	new	903:905	arg1	study					907:911	a new study	901:911	a new study	901:911	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	5	2	theme	diet	652:655	arg1	response					657:664	diet response	652:664	diet response	652:664	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	6	3	theme	several	811:817	arg1	studies					828:834	several clinical studies	811:834	several clinical studies	811:834	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	1	4	theme	macronutrient	144:156	arg1	compositions					158:169	macronutrient compositions	144:169	macronutrient compositions	144:169	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	2	5	theme	different	345:353	arg1	populations					355:365	different populations	345:365	different populations	345:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	6	from	sets	324:327	arg1	populations					355:365	different populations	345:365	different populations	345:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	7	theme	available	288:296	arg1	studies					298:304	available studies	288:304	available studies	288:304	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	5	8	theme	novel	590:594	arg1	model					609:613	a novel mathematical model	588:613	a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver	588:747	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	8	9	theme	specific	1146:1153	arg1	individual					1155:1164	a specific individual	1144:1164	a specific individual's sex	1144:1170	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	2	10	from	variables	332:340	arg1	populations					355:365	different populations	345:365	different populations	345:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	11	theme	diets	275:279	arg1	impact					249:254	the impact	245:254	the impact of these different diets	245:279	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	7	12	dep	glycogen	984:991	arg1	e.g.					971:974	e.g.	971:974	e.g.	971:974	Using this model, we can predict non-measured variables, e.g. hepatic glycogen and gluconeogenesis, in response to fasting and different diets.					
36094958	1	13	theme	compositions	158:169	arg1	combinations					128:139	new combinations	124:139	new combinations of macronutrient compositions and fasting schedules	124:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	6	14	from	studies	828:834	arg1	data					801:804	data	801:804	data from several clinical studies	801:834	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	2	15	from	populations	355:365	arg1	variables					332:340	variables	332:340	variables in different populations	332:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	15	from	populations	355:365	arg1	sets					324:327	different sets	314:327	different sets of variables in different populations	314:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	16	theme	different	265:273	arg1	diets					275:279	these different diets	259:279	these different diets	259:279	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	17	theme	partial	388:394	arg1	insights					411:418	partial, non-connected insights	388:418	partial, non-connected insights	388:418	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	9	18	theme	twin	1297:1300	arg1	technology					1302:1311	an offline digital twin technology	1278:1311	an offline digital twin technology	1278:1311	This tool enables an offline digital twin technology.					
36094958	2	19	theme	different	314:322	arg1	variables					332:340	variables	332:340	variables in different populations	332:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	19	theme	different	314:322	arg1	sets					324:327	different sets	314:327	different sets of variables in different populations	314:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	1	20	theme	fasting	175:181	arg1	schedules					183:191	fasting schedules	175:191	fasting schedules	175:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	0	21	theme	Digital	0:6	arg1	twin					8:11	Digital twin	0:11	Digital twin	0:11	Digital twin predicting diet response before and after long-term fasting.					
36094958	1	22	from	interest	96:103	arg1	diets					108:112	diets	108:112	diets proposing new combinations of macronutrient compositions and fasting schedules	108:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	1	23	theme	schedules	183:191	arg1	combinations					128:139	new combinations	124:139	new combinations of macronutrient compositions and fasting schedules	124:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	0	24	theme	diet	24:27	arg1	response					29:36	diet response	24:36	diet response	24:36	Digital twin predicting diet response before and after long-term fasting.					
36094958	9	25	theme	offline	1281:1287	arg1	technology					1302:1311	an offline digital twin technology	1278:1311	an offline digital twin technology	1278:1311	This tool enables an offline digital twin technology.					
36094958	7	26	theme	different	1041:1049	arg1	diets					1051:1055	different diets	1041:1055	different diets	1041:1055	Using this model, we can predict non-measured variables, e.g. hepatic glycogen and gluconeogenesis, in response to fasting and different diets.					
36094958	5	27	theme	mathematical	596:607	arg1	model					609:613	a novel mathematical model	588:613	a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver	588:747	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	3	28	theme	such	461:464	arg1	insights					474:481	all such partial insights	457:481	all such partial insights into a useful and interconnected big picture	457:526	We lack an approach for integrating all such partial insights into a useful and interconnected big picture.					
36094958	4	29	theme	integrating	556:566	arg1	tool					568:571	such an integrating tool	548:571	such an integrating tool	548:571	Herein, we present such an integrating tool.					
36094958	7	30	theme	hepatic	976:982	arg1	glycogen					984:991	hepatic glycogen	976:991	hepatic glycogen	976:991	Using this model, we can predict non-measured variables, e.g. hepatic glycogen and gluconeogenesis, in response to fasting and different diets.					
36094958	6	31	theme	independent	863:873	arg1	data					875:878	new independent data	859:878	new independent data	859:878	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	6	31	theme	independent	863:873	arg1	data					891:894	data	891:894	data from a new study	891:911	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	1	32	theme	great	90:94	arg1	interest					96:103	great interest	90:103	great interest in diets proposing new combinations of macronutrient compositions and fasting schedules	90:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	3	33	theme	big	516:518	arg1	picture					520:526	a useful and interconnected big picture	488:526	a useful and interconnected big picture	488:526	We lack an approach for integrating all such partial insights into a useful and interconnected big picture.					
36094958	5	34	dep	describes	620:628	arg1	both					696:699	both	696:699	both	696:699	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	3	35	theme	useful	490:495	arg1	picture					520:526	a useful and interconnected big picture	488:526	a useful and interconnected big picture	488:526	We lack an approach for integrating all such partial insights into a useful and interconnected big picture.					
36094958	5	36	theme	organ-organ	705:715	arg1	crosstalk					717:725	organ-organ crosstalk	705:725	organ-organ crosstalk	705:725	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	6	37	theme	new	859:861	arg1	data					875:878	new independent data	859:878	new independent data	859:878	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	6	37	theme	new	859:861	arg1	data					891:894	data	891:894	data from a new study	891:911	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	8	38	theme	historical	1220:1229	arg1	data					1231:1234	the individual's historical data	1203:1234	the individual's historical data on metabolite dynamics	1203:1257	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	8	39	from	data	1231:1234	arg1	dynamics					1250:1257	metabolite dynamics	1239:1257	metabolite dynamics	1239:1257	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	5	40	theme	fasting	670:676	arg1	fluxes					688:693	fasting metabolic fluxes	670:693	fasting metabolic fluxes	670:693	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	2	41	theme	little	218:223	arg1	consensus					225:233	little consensus	218:233	little consensus	218:233	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	3	42	theme	partial	466:472	arg1	insights					474:481	all such partial insights	457:481	all such partial insights into a useful and interconnected big picture	457:526	We lack an approach for integrating all such partial insights into a useful and interconnected big picture.					
36094958	5	43	theme	metabolic	678:686	arg1	fluxes					688:693	fasting metabolic fluxes	670:693	fasting metabolic fluxes	670:693	The tool uses a novel mathematical model that describes mechanisms regulating diet response and fasting metabolic fluxes, both for organ-organ crosstalk, and inside the liver.					
36094958	3	44	theme	interconnected	501:514	arg1	picture					520:526	a useful and interconnected big picture	488:526	a useful and interconnected big picture	488:526	We lack an approach for integrating all such partial insights into a useful and interconnected big picture.					
36094958	2	45	theme	variables	332:340	arg1	variables					332:340	variables	332:340	variables in different populations	332:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	2	45	theme	variables	332:340	arg1	sets					324:327	different sets	314:327	different sets of variables in different populations	314:365	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	8	46	theme	metabolic	1093:1101	arg1	responses					1103:1111	such metabolic responses	1088:1111	such metabolic responses	1088:1111	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	9	47	theme	digital	1289:1295	arg1	technology					1302:1311	an offline digital twin technology	1278:1311	an offline digital twin technology	1278:1311	This tool enables an offline digital twin technology.					
36094958	8	48	theme	such	1088:1091	arg1	responses					1103:1111	such metabolic responses	1088:1111	such metabolic responses	1088:1111	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	8	49	theme	metabolite	1239:1248	arg1	dynamics					1250:1257	metabolite dynamics	1239:1257	metabolite dynamics	1239:1257	Furthermore, we exemplify how such metabolic responses can be successfully adapted to a specific individual's sex, weight, height, as well as to the individual's historical data on metabolite dynamics.					
36094958	7	50	dep	fasting	1029:1035	arg1	response					1017:1024	response	1017:1024	response	1017:1024	Using this model, we can predict non-measured variables, e.g. hepatic glycogen and gluconeogenesis, in response to fasting and different diets.					
36094958	6	51	theme	clinical	819:826	arg1	studies					828:834	several clinical studies	811:834	several clinical studies	811:834	The tool can mechanistically explain and integrate data from several clinical studies, and correctly predict new independent data, including data from a new study.					
36094958	1	52	theme	new	124:126	arg1	combinations					128:139	new combinations	124:139	new combinations of macronutrient compositions and fasting schedules	124:191	Today, there is great interest in diets proposing new combinations of macronutrient compositions and fasting schedules.					
36094958	0	53	theme	long-term	55:63	arg1	fasting					65:71	long-term fasting	55:71	long-term fasting	55:71	Digital twin predicting diet response before and after long-term fasting.					
36094958	2	54	dep	partial	388:394	arg1	non-connected					397:409	non-connected	397:409	non-connected	397:409	Unfortunately, there is little consensus regarding the impact of these different diets, since available studies measure different sets of variables in different populations, thus only providing partial, non-connected insights.					
36094958	7	55	theme	non-measured	947:958	arg1	variables					960:968	non-measured variables	947:968	non-measured variables	947:968	Using this model, we can predict non-measured variables, e.g. hepatic glycogen and gluconeogenesis, in response to fasting and different diets.					
35388969	2	0	theme	{	318:318	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	0	theme	{	318:318	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	0	theme	{	318:318	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	0	theme	{	318:318	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	6	1	theme	portable	1307:1314	arg1	platform					1340:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	1	2	theme	human	254:258	arg1	body					260:263	the human body	250:263	the human body	250:263	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	2	3	from	detection	508:516	arg1	water					555:559	water	555:559	water	555:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	1	4	theme	agricultural	159:170	arg1	industry					172:179	the modern agricultural industry	148:179	the modern agricultural industry	148:179	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	5	5	dep	SA	1217:1218	arg1	qmax					1221:1224	qmax	1221:1224	qmax = 161.8 mg g-1	1221:1239	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	3	6	theme	nitrogen-rich	574:586	arg1	sites					588:592	The exposed nitrogen-rich sites	562:592	The exposed nitrogen-rich sites	562:592	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	4	7	theme	low	993:995	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	7	theme	low	993:995	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	3	8	theme	MOF-on-MOF-sodium	673:689	arg1	alginate					691:698	MOF-on-MOF-sodium alginate	673:698	MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite	673:726	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	3	8	theme	MOF-on-MOF-sodium	673:689	arg1	SA					714:715	ZIF-8-on-Zn2@SA	701:715	ZIF-8-on-Zn2@SA	701:715	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	2	9	theme	=	384:384	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	9	theme	=	384:384	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	6	10	theme	promising	1360:1368	arg1	candidate					1370:1378	a promising candidate	1358:1378	a promising candidate for monitoring and removal of pesticides	1358:1419	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	2	11	theme	on-site	500:506	arg1	detection					508:516	visual and on-site detection	489:516	visual and on-site detection of pesticides and their removal from water	489:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	4	12	theme	fluorescent	795:805	arg1	emission					807:814	the excellent fluorescent emission	781:814	the excellent fluorescent emission of Zn2	781:821	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	13	theme	linear	959:964	arg1	range					966:970	a broad linear range	951:970	a broad linear range (10-100 × 10-6 m)	951:988	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	13	theme	linear	959:964	arg1	m					987:987	10-100 × 10-6 m	973:987	10-100 × 10-6 m	973:987	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	3	14	theme	chemical	603:610	arg1	stability					612:620	high chemical stability	598:620	high chemical stability	598:620	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	4	15	from	detection	879:887	arg1	fruits					924:929	real fruits	919:929	real fruits	919:929	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	15	from	detection	879:887	arg1	vegetables					935:944	vegetables	935:944	vegetables	935:944	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	3	16	theme	@	713:713	arg1	alginate					691:698	MOF-on-MOF-sodium alginate	673:698	MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite	673:726	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	3	16	theme	@	713:713	arg1	SA					714:715	ZIF-8-on-Zn2@SA	701:715	ZIF-8-on-Zn2@SA	701:715	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	5	17	theme	ZIF-8-on-Zn2	1204:1215	arg1	SA					1217:1218	the ZIF-8-on-Zn2@SA	1200:1218	the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 )	1200:1241	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	2	18	dep	[Zn2	350:353	arg1	bdc					363:365	bdc	363:365	bdc	363:365	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	18	dep	[Zn2	350:353	arg1	tpt					356:358	tpt)2	356:360	tpt)2 (bdc)	356:366	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	0	19	theme	Effective	79:87	arg1	Removal					89:95	Effective Removal	79:95	Effective Removal	79:95	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	6	20	theme	SA	1329:1330	arg1	platform					1340:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	4	21	theme	=	1021:1021	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	21	theme	=	1021:1021	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	2	22	theme	O	334:334	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	22	theme	O	334:334	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	22	theme	O	334:334	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	22	theme	O	334:334	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	6	23	theme	ZIF-8-on-Zn2	1316:1327	arg1	platform					1340:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	4	24	theme	@	849:849	arg1	module					853:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	2	25	theme	visual	489:494	arg1	detection					508:516	visual and on-site detection	489:516	visual and on-site detection of pesticides and their removal from water	489:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	0	26	theme	Smart	0:4	arg1	Hydrogel					17:24	Smart MOF-on-MOF Hydrogel	0:24	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.	0:110	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	2	27	theme	removal	542:548	arg1	detection					508:516	visual and on-site detection	489:516	visual and on-site detection of pesticides and their removal from water	489:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	4	28	theme	satisfactory	1043:1054	arg1	recoveries					1056:1065	satisfactory recoveries	1043:1065	satisfactory recoveries (98.30-102.70%)	1043:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	28	theme	satisfactory	1043:1054	arg1	%					1080:1080	98.30-102.70%	1068:1080	98.30-102.70%	1068:1080	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	2	29	theme	}	336:336	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	29	theme	}	336:336	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	29	theme	}	336:336	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	29	theme	}	336:336	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	4	30	with	vegetables	935:944	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	30	with	vegetables	935:944	arg1	m					987:987	10-100 × 10-6 m	973:987	10-100 × 10-6 m	973:987	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	30	with	vegetables	935:944	arg1	%					1080:1080	98.30-102.70%	1068:1080	98.30-102.70%	1068:1080	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	30	with	vegetables	935:944	arg1	range					966:970	a broad linear range	951:970	a broad linear range (10-100 × 10-6 m)	951:988	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	30	with	vegetables	935:944	arg1	recoveries					1056:1065	satisfactory recoveries	1043:1065	satisfactory recoveries (98.30-102.70%)	1043:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	30	with	vegetables	935:944	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	31	theme	rod-like	828:835	arg1	module					853:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	6	32	theme	environmental	1477:1489	arg1	pollution					1491:1499	serious pesticide environmental pollution	1459:1499	serious pesticide environmental pollution	1459:1499	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	0	33	theme	Rod-shaped	38:47	arg1	Core					49:52	a Simple Rod-shaped Core	29:52	a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides	29:109	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	4	34	with	fruits	924:929	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	34	with	fruits	924:929	arg1	m					987:987	10-100 × 10-6 m	973:987	10-100 × 10-6 m	973:987	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	34	with	fruits	924:929	arg1	%					1080:1080	98.30-102.70%	1068:1080	98.30-102.70%	1068:1080	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	34	with	fruits	924:929	arg1	range					966:970	a broad linear range	951:970	a broad linear range (10-100 × 10-6 m)	951:988	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	34	with	fruits	924:929	arg1	recoveries					1056:1065	satisfactory recoveries	1043:1065	satisfactory recoveries (98.30-102.70%)	1043:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	34	with	fruits	924:929	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	6	35	theme	serious	1459:1465	arg1	pollution					1491:1499	serious pesticide environmental pollution	1459:1499	serious pesticide environmental pollution	1459:1499	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	1	36	theme	pesticides	134:143	arg1	use					127:129	The immoderate use	112:129	The immoderate use of pesticides in the modern agricultural industry	112:179	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	2	37	theme	tpt	323:325	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	37	theme	tpt	323:325	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	37	theme	tpt	323:325	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	37	theme	tpt	323:325	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	1	38	theme	resources	215:223	arg1	pollution					196:204	the pollution	192:204	the pollution of water resources	192:223	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	2	39	dep	Htpt	379:382	arg1	phenyl-2H-tetrazole					414:432	phenyl-2H-tetrazole	414:432	phenyl-2H-tetrazole	414:432	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	4	40	theme	naked-eye	869:877	arg1	detection					879:887	naked-eye detection	869:887	naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%)	869:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	2	41	theme	[Zn	319:321	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	41	theme	[Zn	319:321	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	41	theme	[Zn	319:321	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	41	theme	[Zn	319:321	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	5	42	theme	correlation	1255:1265	arg1	R2					1280:1281	R2 > 0.99	1280:1288	R2 > 0.99	1280:1288	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	42	theme	correlation	1255:1265	arg1	coefficient					1267:1277	a high correlation coefficient	1248:1277	a high correlation coefficient (R2 > 0.99)	1248:1289	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	1	43	theme	modern	152:157	arg1	industry					172:179	the modern agricultural industry	148:179	the modern agricultural industry	148:179	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	5	44	dep	=	1226:1226	arg1	mg g-1					1234:1239	161.8 mg g-1	1228:1239	161.8 mg g-1	1228:1239	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	4	45	theme	broad	953:957	arg1	range					966:970	a broad linear range	951:970	a broad linear range (10-100 × 10-6 m)	951:988	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	45	theme	broad	953:957	arg1	m					987:987	10-100 × 10-6 m	973:987	10-100 × 10-6 m	973:987	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	46	theme	real	919:922	arg1	fruits					924:929	real fruits	919:929	real fruits	919:929	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	3	47	theme	exposed	566:572	arg1	sites					588:592	The exposed nitrogen-rich sites	562:592	The exposed nitrogen-rich sites	562:592	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	2	48	theme	metal-organic	278:290	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	48	theme	metal-organic	278:290	arg1	MOFs					304:307	MOFs	304:307	MOFs	304:307	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	48	theme	metal-organic	278:290	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	48	theme	metal-organic	278:290	arg1	materials					475:483	smart materials	469:483	smart materials for visual and on-site detection of pesticides and their removal from water	469:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	48	theme	metal-organic	278:290	arg1	[Zn2					350:353	{[Zn2	349:353	{[Zn2 (tpt)2 (bdc)]	349:367	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	4	49	theme	LOD	1017:1019	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	49	theme	LOD	1017:1019	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	2	50	theme	pesticides	521:530	arg1	detection					508:516	visual and on-site detection	489:516	visual and on-site detection of pesticides and their removal from water	489:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	3	51	theme	high	598:601	arg1	stability					612:620	high chemical stability	598:620	high chemical stability	598:620	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	1	52	theme	immoderate	116:125	arg1	use					127:129	The immoderate use	112:129	The immoderate use of pesticides in the modern agricultural industry	112:179	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	3	53	theme	alginate	691:698	arg1	composite					718:726	MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite	673:726	MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite	673:726	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	6	54	with	regions	1446:1452	arg1	pollution					1491:1499	serious pesticide environmental pollution	1459:1499	serious pesticide environmental pollution	1459:1499	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	0	55	theme	Visual	58:63	arg1	Detection					65:73	Visual Detection	58:73	Visual Detection	58:73	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	4	56	theme	excellent	785:793	arg1	emission					807:814	the excellent fluorescent emission	781:814	the excellent fluorescent emission of Zn2	781:821	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	5	57	theme	@	1216:1216	arg1	SA					1217:1218	the ZIF-8-on-Zn2@SA	1200:1218	the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 )	1200:1241	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	2	58	theme	smart	469:473	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	58	theme	smart	469:473	arg1	materials					475:483	smart materials	469:483	smart materials for visual and on-site detection of pesticides and their removal from water	469:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	6	59	theme	sensing	1332:1338	arg1	platform					1340:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	3	60	theme	ZIF-8-on-Zn2	701:712	arg1	alginate					691:698	MOF-on-MOF-sodium alginate	673:698	MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite	673:726	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	3	60	theme	ZIF-8-on-Zn2	701:712	arg1	SA					714:715	ZIF-8-on-Zn2@SA	701:715	ZIF-8-on-Zn2@SA	701:715	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	3	61	theme	self-assembly	633:645	arg1	core					647:650	a self-assembly core	631:650	a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface	631:767	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	0	62	theme	Pesticides	100:109	arg1	Detection					65:73	Visual Detection	58:73	Visual Detection	58:73	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	0	62	theme	Pesticides	100:109	arg1	Removal					89:95	Effective Removal	79:95	Effective Removal	79:95	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	6	63	theme	@	1328:1328	arg1	platform					1340:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	the portable ZIF-8-on-Zn2@SA sensing platform	1303:1347	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	6	64	theme	pesticides	1410:1419	arg1	monitoring					1384:1393	monitoring	1384:1393	monitoring	1384:1393	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	6	64	theme	pesticides	1410:1419	arg1	removal					1399:1405	removal	1399:1405	removal of pesticides	1399:1419	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	2	65	theme	·2H2	329:332	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	65	theme	·2H2	329:332	arg1	Zn1					340:342	Zn1	340:342	Zn1	340:342	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	65	theme	·2H2	329:332	arg1	n					337:337	{[Zn(tpt)2 ·2H2 O]}n	318:337	{[Zn(tpt)2 ·2H2 O]}n (Zn1)	318:343	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	65	theme	·2H2	329:332	arg1	Htpt					379:382	Htpt	379:382	Htpt = 5-[4(1H-1,2,4-triazol-1-yl)	379:412	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	0	66	theme	MOF-on-MOF	6:15	arg1	Hydrogel					17:24	Smart MOF-on-MOF Hydrogel	0:24	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.	0:110	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	1	67	from	use	127:129	arg1	industry					172:179	the modern agricultural industry	148:179	the modern agricultural industry	148:179	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	4	68	theme	ZIF-8-on-Zn2	837:848	arg1	module					853:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	m					1035:1035	LOD = 0.14 × 10-6 m	1017:1035	LOD = 0.14 × 10-6 m	1017:1035	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	m					987:987	10-100 × 10-6 m	973:987	10-100 × 10-6 m	973:987	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	%					1080:1080	98.30-102.70%	1068:1080	98.30-102.70%	1068:1080	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	range					966:970	a broad linear range	951:970	a broad linear range (10-100 × 10-6 m)	951:988	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	recoveries					1056:1065	satisfactory recoveries	1043:1065	satisfactory recoveries (98.30-102.70%)	1043:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	4	69	theme	detection	1006:1014	arg1	limit					997:1001	a low limit	991:1001	a low limit of detection (LOD = 0.14 × 10-6 m)	991:1036	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	5	70	attach	removed	1178:1184	arg2	CBZ					1110:1112	CBZ	1110:1112	CBZ	1110:1112	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	70	attach	removed	1178:1184	arg2	carbendazim					1097:1107	carbendazim	1097:1107	carbendazim (CBZ)	1097:1113	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	70	attach	removed	1178:1184	arg1	water					1191:1195	water	1191:1195	water	1191:1195	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	70	attach	removed	1178:1184	arg2	metabolite					1120:1129	the metabolite	1116:1129	the metabolite of TM after usage in crops	1116:1156	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	3	71	theme	outside	753:759	arg1	surface					761:767	the outside surface	749:767	the outside surface	749:767	The exposed nitrogen-rich sites and high chemical stability make Zn2 a self-assembly core to further fabricate MOF-on-MOF-sodium alginate (ZIF-8-on-Zn2@SA) composite by wrapping ZIF-8 on the outside surface.					
35388969	4	72	theme	SA	850:851	arg1	module					853:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	the rod-like ZIF-8-on-Zn2@SA module	824:858	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	0	73	theme	Simple	31:36	arg1	Core					49:52	a Simple Rod-shaped Core	29:52	a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides	29:109	Smart MOF-on-MOF Hydrogel as a Simple Rod-shaped Core for Visual Detection and Effective Removal of Pesticides.					
35388969	4	74	theme	Zn2	819:821	arg1	emission					807:814	the excellent fluorescent emission	781:814	the excellent fluorescent emission of Zn2	781:821	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	5	75	theme	high	1250:1253	arg1	R2					1280:1281	R2 > 0.99	1280:1288	R2 > 0.99	1280:1288	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	75	theme	high	1250:1253	arg1	coefficient					1267:1277	a high correlation coefficient	1248:1277	a high correlation coefficient (R2 > 0.99)	1248:1289	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	2	76	from	water	555:559	arg1	pesticides					521:530	pesticides	521:530	pesticides	521:530	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	76	from	water	555:559	arg1	removal					542:548	their removal	536:548	their removal from water	536:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	76	from	water	555:559	arg1	detection					508:516	visual and on-site detection	489:516	visual and on-site detection of pesticides and their removal from water	489:559	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	6	77	theme	pesticide	1467:1475	arg1	pollution					1491:1499	serious pesticide environmental pollution	1459:1499	serious pesticide environmental pollution	1459:1499	Therefore, the portable ZIF-8-on-Zn2@SA sensing platform presents a promising candidate for monitoring and removal of pesticides, especially suitable for regions with serious pesticide environmental pollution.					
35388969	5	78	theme	=	1226:1226	arg1	qmax					1221:1224	qmax	1221:1224	qmax = 161.8 mg g-1	1221:1239	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	2	79	dep	n	337:337	arg1	Zn2					372:374	Zn2	372:374	Zn2	372:374	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	79	dep	n	337:337	arg1	n					369:369	}n	368:369	}n (Zn2)	368:375	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	5	80	theme	TM	1134:1135	arg1	carbendazim					1097:1107	carbendazim	1097:1107	carbendazim (CBZ)	1097:1113	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	80	theme	TM	1134:1135	arg1	metabolite					1120:1129	the metabolite	1116:1129	the metabolite of TM after usage in crops	1116:1156	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	5	81	from	usage	1143:1147	arg1	crops					1152:1156	crops	1152:1156	crops	1152:1156	In addition, carbendazim (CBZ), the metabolite of TM after usage in crops, can be efficiently removed from water by the ZIF-8-on-Zn2@SA (qmax = 161.8 mg g-1 ) with a high correlation coefficient (R2 > 0.99).					
35388969	4	82	theme	thiophanate-methyl	892:909	arg1	detection					879:887	naked-eye detection	869:887	naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%)	869:1081	Inheriting the excellent fluorescent emission of Zn2, the rod-like ZIF-8-on-Zn2@SA module exhibits naked-eye detection of thiophanate-methyl (TM) in real fruits and vegetables with a broad linear range (10-100 × 10-6 m), a low limit of detection (LOD = 0.14 × 10-6 m), and satisfactory recoveries (98.30-102.70%).					
35388969	1	83	theme	water	209:213	arg1	resources					215:223	water resources	209:223	water resources	209:223	The immoderate use of pesticides in the modern agricultural industry has led to the pollution of water resources and ultimately threatens the human body.					
35388969	2	84	dep	=	384:384	arg1	1H-1,2,4-triazol-1-yl					391:411	1H-1,2,4-triazol-1-yl	391:411	1H-1,2,4-triazol-1-yl	391:411	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	84	dep	=	384:384	arg1	5-[4					386:389	5-[4	386:389	5-[4	386:389	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	85	theme	{	349:349	arg1	frameworks					292:301	two metal-organic frameworks	274:301	two metal-organic frameworks (MOFs)	274:308	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
35388969	2	85	theme	{	349:349	arg1	[Zn2					350:353	{[Zn2	349:353	{[Zn2 (tpt)2 (bdc)]	349:367	Herein, two metal-organic frameworks (MOFs), namely {[Zn(tpt)2 ·2H2 O]}n (Zn1) and {[Zn2 (tpt)2 (bdc)]}n (Zn2), (Htpt = 5-[4(1H-1,2,4-triazol-1-yl)]phenyl-2H-tetrazole), respectively, are constructed as smart materials for visual and on-site detection of pesticides and their removal from water.					
36244540	0	0	theme	alcohol	93:99	arg1	film					112:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	5	1	contain	had	746:748	arg2	effect					779:784	a long-lasting antibacterial effect	750:784	a long-lasting antibacterial effect	750:784	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	5	1	contain	had	746:748	arg1	which					740:744	which	740:744	which	740:744	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	6	2	from	effect	908:913	arg1	applications					947:958	fresh-cut apple preservation applications	918:958	fresh-cut apple preservation applications	918:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	0	3	theme	vinyl	87:91	arg1	film					112:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	7	4	theme	products	1105:1112	arg1	life					1092:1095	the shelf life	1082:1095	the shelf life of food products	1082:1112	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	7	5	theme	food	1100:1103	arg1	products					1105:1112	food products	1100:1112	food products	1100:1112	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	0	6	theme	composite	102:110	arg1	film					112:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	5	7	theme	Ag+	688:690	arg1	0.686 ± 0.022 mg·L-1					701:720	0.686 ± 0.022 mg·L-1	701:720	0.686 ± 0.022 mg·L-1	701:720	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	5	7	theme	Ag+	688:690	arg1	release					677:683	the release	673:683	the release of Ag+	673:690	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	7	8	contain	has	1004:1006	arg1	film					999:1002	CG/PVA/AgNPs composite film	976:1002	CG/PVA/AgNPs composite film	976:1002	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	7	8	contain	has	1004:1006	arg2	applications					1018:1029	potential applications	1008:1029	potential applications	1008:1029	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	6	9	theme	composite	840:848	arg1	film					850:853	CG/PVA/AgNPs-2 composite film	825:853	CG/PVA/AgNPs-2 composite film	825:853	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	4	10	theme	@	596:596	arg1	CG					597:598	The AgNPs@CG	587:598	The AgNPs@CG	587:598	The AgNPs@CG was incorporated into the CG/PVA composite film.					
36244540	1	11	theme	serious	164:170	arg1	threat					172:177	a serious threat	162:177	a serious threat to human health	162:193	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	1	11	theme	serious	164:170	arg1	spoilage					123:130	Food spoilage	118:130	Food spoilage caused by bacterial growth	118:157	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	6	12	theme	CG/PVA/AgNPs-2	825:838	arg1	film					850:853	CG/PVA/AgNPs-2 composite film	825:853	CG/PVA/AgNPs-2 composite film	825:853	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	6	13	theme	preservation	934:945	arg1	applications					947:958	fresh-cut apple preservation applications	918:958	fresh-cut apple preservation applications	918:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	2	14	theme	pathogenic	269:278	arg1	microorganisms					280:293	various pathogenic microorganisms	261:293	various pathogenic microorganisms	261:293	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	5	15	theme	long-lasting	752:763	arg1	effect					779:784	a long-lasting antibacterial effect	750:784	a long-lasting antibacterial effect	750:784	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	3	16	theme	long-lasting	536:547	arg1	release					571:577	a long-lasting and stable controlled release	534:577	a long-lasting and stable controlled release of Ag+	534:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	4	17	theme	composite	633:641	arg1	film					643:646	the CG/PVA composite film	622:646	the CG/PVA composite film	622:646	The AgNPs@CG was incorporated into the CG/PVA composite film.					
36244540	0	18	theme	Gallic	0:5	arg1	acid					7:10	Gallic acid	0:10	Gallic acid	0:10	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	1	19	theme	human	182:186	arg1	health					188:193	human health	182:193	human health	182:193	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	0	20	theme	chitosan	27:34	arg1	nanosilver					48:57	chitosan immobilized nanosilver	27:57	chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film	27:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	5	21	theme	antibacterial	765:777	arg1	effect					779:784	a long-lasting antibacterial effect	750:784	a long-lasting antibacterial effect	750:784	The results showed that the release of Ag+ was only 0.686 ± 0.022 mg·L-1 after seven days, which had a long-lasting antibacterial effect on E. coli and S. aureus.					
36244540	7	22	theme	packaging	1053:1061	arg1	material					1063:1070	effective and safe packaging material	1034:1070	effective and safe packaging material	1034:1070	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	2	23	theme	rapid	306:310	arg1	release					312:318	their rapid release	300:318	their rapid release	300:318	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	7	24	theme	shelf	1086:1090	arg1	life					1092:1095	the shelf life	1082:1095	the shelf life of food products	1082:1112	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	3	25	theme	silver	371:376	arg1	nanoparticles					378:390	silver nanoparticles	371:390	silver nanoparticles (AgNPs@CG)	371:401	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	25	theme	silver	371:376	arg1	CG					399:400	AgNPs@CG	393:400	AgNPs@CG	393:400	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	6	26	theme	apple	928:932	arg1	applications					947:958	fresh-cut apple preservation applications	918:958	fresh-cut apple preservation applications	918:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	3	27	theme	gallic	446:451	arg1	agent					517:521	a reducing and stabilizing agent	490:521	a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+	490:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	27	theme	gallic	446:451	arg1	CG					483:484	CG	483:484	CG	483:484	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	27	theme	gallic	446:451	arg1	chitosan					473:480	gallic acid-functionalized chitosan	446:480	gallic acid-functionalized chitosan (CG)	446:485	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	6	28	theme	fresh-cut	918:926	arg1	applications					947:958	fresh-cut apple preservation applications	918:958	fresh-cut apple preservation applications	918:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	4	29	theme	CG/PVA	626:631	arg1	film					643:646	the CG/PVA composite film	622:646	the CG/PVA composite film	622:646	The AgNPs@CG was incorporated into the CG/PVA composite film.					
36244540	0	30	theme	immobilized	36:46	arg1	nanosilver					48:57	chitosan immobilized nanosilver	27:57	chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film	27:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	7	31	theme	safe	1048:1051	arg1	material					1063:1070	effective and safe packaging material	1034:1070	effective and safe packaging material	1034:1070	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	3	32	theme	AgNPs	393:397	arg1	nanoparticles					378:390	silver nanoparticles	371:390	silver nanoparticles (AgNPs@CG)	371:401	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	32	theme	AgNPs	393:397	arg1	CG					399:400	AgNPs@CG	393:400	AgNPs@CG	393:400	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	0	33	theme	chitosan/Poly	72:84	arg1	film					112:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	3	34	theme	stable	553:558	arg1	release					571:577	a long-lasting and stable controlled release	534:577	a long-lasting and stable controlled release of Ag+	534:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	1	35	theme	Food	118:121	arg1	spoilage					123:130	Food spoilage	118:130	Food spoilage caused by bacterial growth	118:157	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	1	35	theme	Food	118:121	arg1	threat					172:177	a serious threat	162:177	a serious threat to human health	162:193	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	3	36	theme	@	398:398	arg1	nanoparticles					378:390	silver nanoparticles	371:390	silver nanoparticles (AgNPs@CG)	371:401	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	36	theme	@	398:398	arg1	CG					399:400	AgNPs@CG	393:400	AgNPs@CG	393:400	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	6	37	theme	preservation	895:906	arg1	effect					908:913	the freshness preservation effect	881:913	the freshness preservation effect in fresh-cut apple preservation applications	881:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	7	38	theme	effective	1034:1042	arg1	material					1063:1070	effective and safe packaging material	1034:1070	effective and safe packaging material	1034:1070	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	3	39	theme	controlled	560:569	arg1	release					571:577	a long-lasting and stable controlled release	534:577	a long-lasting and stable controlled release of Ag+	534:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	7	40	theme	CG/PVA/AgNPs	976:987	arg1	film					999:1002	CG/PVA/AgNPs composite film	976:1002	CG/PVA/AgNPs composite film	976:1002	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	2	41	theme	cumulative	335:344	arg1	toxicity					346:353	cumulative toxicity	335:353	cumulative toxicity	335:353	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	6	42	theme	freshness	885:893	arg1	effect					908:913	the freshness preservation effect	881:913	the freshness preservation effect in fresh-cut apple preservation applications	881:958	In addition, CG/PVA/AgNPs-2 composite film can significantly improve the freshness preservation effect in fresh-cut apple preservation applications.					
36244540	7	43	theme	potential	1008:1016	arg1	applications					1018:1029	potential applications	1008:1029	potential applications	1008:1029	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	2	44	theme	Silver	196:201	arg1	AgNPs					218:222	AgNPs	218:222	AgNPs	218:222	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	2	44	theme	Silver	196:201	arg1	nanoparticles					203:215	Silver nanoparticles	196:215	Silver nanoparticles (AgNPs)	196:223	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	2	45	theme	various	261:267	arg1	microorganisms					280:293	various pathogenic microorganisms	261:293	various pathogenic microorganisms	261:293	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	7	46	theme	composite	989:997	arg1	film					999:1002	CG/PVA/AgNPs composite film	976:1002	CG/PVA/AgNPs composite film	976:1002	In conclusion, CG/PVA/AgNPs composite film has potential applications as effective and safe packaging material to extend the shelf life of food products.					
36244540	3	47	theme	acid-functionalized	453:471	arg1	agent					517:521	a reducing and stabilizing agent	490:521	a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+	490:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	47	theme	acid-functionalized	453:471	arg1	CG					483:484	CG	483:484	CG	483:484	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	47	theme	acid-functionalized	453:471	arg1	chitosan					473:480	gallic acid-functionalized chitosan	446:480	gallic acid-functionalized chitosan (CG)	446:485	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	48	theme	stabilizing	505:515	arg1	agent					517:521	a reducing and stabilizing agent	490:521	a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+	490:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	48	theme	stabilizing	505:515	arg1	chitosan					473:480	gallic acid-functionalized chitosan	446:480	gallic acid-functionalized chitosan (CG)	446:485	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	49	theme	Ag+	582:584	arg1	release					571:577	a long-lasting and stable controlled release	534:577	a long-lasting and stable controlled release of Ag+	534:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	1	50	theme	bacterial	142:150	arg1	growth					152:157	bacterial growth	142:157	bacterial growth	142:157	Food spoilage caused by bacterial growth is a serious threat to human health.					
36244540	4	51	theme	AgNPs	591:595	arg1	CG					597:598	The AgNPs@CG	587:598	The AgNPs@CG	587:598	The AgNPs@CG was incorporated into the CG/PVA composite film.					
36244540	0	52	theme	modified	63:70	arg1	film					112:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	modified chitosan/Poly (vinyl alcohol) composite film	63:115	Gallic acid functionalized chitosan immobilized nanosilver for modified chitosan/Poly (vinyl alcohol) composite film.					
36244540	2	53	theme	antibacterial	230:242	arg1	activity					244:251	antibacterial activity	230:251	antibacterial activity against various pathogenic microorganisms	230:293	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	3	54	theme	reducing	492:499	arg1	agent					517:521	a reducing and stabilizing agent	490:521	a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+	490:584	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	3	54	theme	reducing	492:499	arg1	chitosan					473:480	gallic acid-functionalized chitosan	446:480	gallic acid-functionalized chitosan (CG)	446:485	In this paper, silver nanoparticles (AgNPs@CG) were reduced and immobilized in situ using gallic acid-functionalized chitosan (CG) as a reducing and stabilizing agent to achieve a long-lasting and stable controlled release of Ag+.					
36244540	2	55	contain	have	225:228	arg2	activity					244:251	antibacterial activity	230:251	antibacterial activity against various pathogenic microorganisms	230:293	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	2	55	contain	have	225:228	arg1	AgNPs					218:222	AgNPs	218:222	AgNPs	218:222	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
36244540	2	55	contain	have	225:228	arg1	nanoparticles					203:215	Silver nanoparticles	196:215	Silver nanoparticles (AgNPs)	196:223	Silver nanoparticles (AgNPs) have antibacterial activity against various pathogenic microorganisms, but their rapid release often leads to cumulative toxicity.					
35020918	5	0	theme	lesion	753:758	arg1	diameters					760:768	the lesion diameters	749:768	the lesion diameters	749:768	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	1	1	theme	UV	167:168	arg1	effect					184:189	the UV light-induced effect	163:189	the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii	163:295	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	6	2	theme	nucleic	996:1002	arg1	material					1009:1016	nucleic acid material	996:1016	nucleic acid material	996:1016	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	1	3	theme	light-induced	170:182	arg1	effect					184:189	the UV light-induced effect	163:189	the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii	163:295	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	7	4	from	dismutase	1061:1069	arg1	cells					1089:1093	the P. steckii cells	1074:1093	the P. steckii cells	1074:1093	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	7	5	dep	maximum	1103:1109	arg1	concentrations					1111:1124	concentrations	1111:1124	maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively)	1103:1183	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	8	6	theme	film	1326:1329	arg1	solution					1331:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	6	7	theme	protein	984:990	arg1	extravasation					953:965	serious extravasation	945:965	serious extravasation of intracellular protein and nucleic acid material	945:1016	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	6	8	theme	intracellular	970:982	arg1	protein					984:990	intracellular protein	970:990	intracellular protein	970:990	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	8	9	theme	nanocomposite	1312:1324	arg1	solution					1331:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	1	10	theme	underlying	305:314	arg1	mechanism					330:338	the underlying physiological mechanism	301:338	the underlying physiological mechanism of this effect	301:353	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	5	11	theme	same	732:735	arg1	conditions					737:746	the same conditions	728:746	the same conditions	728:746	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	6	12	theme	cell	871:874	arg1	membrane					876:883	the P. steckii cell membrane	856:883	the P. steckii cell membrane	856:883	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	7	13	dep	μmol/mL	1134:1140	arg1	U/mL					1149:1152	44.06 U/mL	1143:1152	44.06 U/mL	1143:1152	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	7	13	dep	μmol/mL	1134:1140	arg1	U/mL					1165:1168	24.67 U/mL	1159:1168	24.67 U/mL	1159:1168	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	5	14	theme	mangoes	797:803	arg1	proportion					774:783	proportion	774:783	proportion of infected mangoes	774:803	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	5	14	theme	mangoes	797:803	arg1	diameters					760:768	the lesion diameters	749:768	the lesion diameters	749:768	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	5	15	from	period	704:709	arg1	mangoes					714:720	mangoes	714:720	mangoes	714:720	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	3	16	theme	colony	488:493	arg1	diameter					495:502	the smallest P. steckii colony diameter	464:502	the smallest P. steckii colony diameter	464:502	UV-photoinduced treatment for 120 min produced the smallest P. steckii colony diameter, at 4.85 mm.					
35020918	4	17	theme	P.	602:603	arg1	medium					621:626	the P. steckii culture medium	598:626	the P. steckii culture medium	598:626	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	7	18	theme	44.06	1143:1147	arg1	U/mL					1149:1152	44.06 U/mL	1143:1152	44.06 U/mL	1143:1152	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	4	19	theme	culture	613:619	arg1	medium					621:626	the P. steckii culture medium	598:626	the P. steckii culture medium	598:626	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	0	20	theme	Antifungal	14:23	arg1	Activity					25:32	Photo-Induced Antifungal Activity	0:32	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.	0:112	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	6	21	theme	P.	860:861	arg1	membrane					876:883	the P. steckii cell membrane	856:883	the P. steckii cell membrane	856:883	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	7	22	theme	P.	1078:1079	arg1	cells					1089:1093	the P. steckii cells	1074:1093	the P. steckii cells	1074:1093	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	2	23	theme	longer	361:366	arg1	time					380:383	longer UV exposure time	361:383	longer UV exposure time	361:383	With longer UV exposure time, pathogen inhibition increased.					
35020918	7	24	theme	24.67	1159:1163	arg1	U/mL					1165:1168	24.67 U/mL	1159:1168	24.67 U/mL	1159:1168	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	3	25	theme	P.	477:478	arg1	diameter					495:502	the smallest P. steckii colony diameter	464:502	the smallest P. steckii colony diameter	464:502	UV-photoinduced treatment for 120 min produced the smallest P. steckii colony diameter, at 4.85 mm.					
35020918	0	26	theme	Photo-Induced	0:12	arg1	Activity					25:32	Photo-Induced Antifungal Activity	0:32	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.	0:112	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	1	27	theme	physiological	316:328	arg1	mechanism					330:338	the underlying physiological mechanism	301:338	the underlying physiological mechanism of this effect	301:353	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	7	28	theme	steckii	1081:1087	arg1	cells					1089:1093	the P. steckii cells	1074:1093	the P. steckii cells	1074:1093	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	8	29	theme	significant	1233:1243	arg1	inhibition					1256:1265	significant P. steckii inhibition	1233:1265	significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution	1233:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	3	30	theme	UV-photoinduced	417:431	arg1	treatment					433:441	UV-photoinduced treatment	417:441	UV-photoinduced treatment for 120 min	417:453	UV-photoinduced treatment for 120 min produced the smallest P. steckii colony diameter, at 4.85 mm.					
35020918	4	31	theme	storage	569:575	arg1	h					564:564	8 h	562:564	8 h of storage	562:575	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	5	32	theme	growth	697:702	arg1	period					704:709	a 120-h growth period	689:709	a 120-h growth period on mangoes under the same conditions	689:746	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	8	33	dep	significant	1233:1243	arg1	P.					1245:1246	P.	1245:1246	P.	1245:1246	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	7	34	dep	concentrations	1111:1124	arg1	μmol/mL					1134:1140	2.1106 μmol/mL	1127:1140	2.1106 μmol/mL	1127:1140	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	6	35	theme	serious	945:951	arg1	extravasation					953:965	serious extravasation	945:965	serious extravasation of intracellular protein and nucleic acid material	945:1016	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	8	36	dep	P.	1245:1246	arg1	steckii					1248:1254	steckii	1248:1254	steckii	1248:1254	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	2	37	theme	pathogen	386:393	arg1	inhibition					395:404	pathogen inhibition	386:404	pathogen inhibition	386:404	With longer UV exposure time, pathogen inhibition increased.					
35020918	4	38	theme	highest	640:646	arg1	level					648:652	its highest level	636:652	its highest level	636:652	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	0	39	theme	Composite	46:54	arg1	Solution					61:68	Chitosan Composite Film Solution	37:68	Chitosan Composite Film Solution	37:68	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	7	40	theme	superoxide	1050:1059	arg1	dismutase					1061:1069	superoxide dismutase	1050:1069	superoxide dismutase	1050:1069	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	4	41	dep	P.	602:603	arg1	steckii					605:611	steckii	605:611	steckii	605:611	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	3	42	dep	P.	477:478	arg1	steckii					480:486	steckii	480:486	steckii	480:486	UV-photoinduced treatment for 120 min produced the smallest P. steckii colony diameter, at 4.85 mm.					
35020918	6	43	dep	P.	860:861	arg1	steckii					863:869	steckii	863:869	steckii	863:869	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	0	44	theme	Chitosan	37:44	arg1	Solution					61:68	Chitosan Composite Film Solution	37:68	Chitosan Composite Film Solution	37:68	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	1	45	theme	effect	348:353	arg1	effect					184:189	the UV light-induced effect	163:189	the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii	163:295	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	1	45	theme	effect	348:353	arg1	mechanism					330:338	the underlying physiological mechanism	301:338	the underlying physiological mechanism of this effect	301:353	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	3	46	theme	smallest	468:475	arg1	diameter					495:502	the smallest P. steckii colony diameter	464:502	the smallest P. steckii colony diameter	464:502	UV-photoinduced treatment for 120 min produced the smallest P. steckii colony diameter, at 4.85 mm.					
35020918	8	47	theme	UV	1274:1275	arg1	light					1277:1281	UV light	1274:1281	the UV light induction of the CTS-TiO2-Ag nanocomposite film solution	1270:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	1	48	theme	nanocomposite	241:253	arg1	solution					260:267	chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution	194:267	chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution	194:267	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	0	49	theme	Solution	61:68	arg1	Activity					25:32	Photo-Induced Antifungal Activity	0:32	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.	0:112	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	5	50	theme	infected	788:795	arg1	mangoes					797:803	infected mangoes	788:803	infected mangoes	788:803	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	0	51	with	Activity	25:32	arg1	Dioxide					89:95	Nano-Titanium Dioxide	75:95	Nano-Titanium Dioxide	75:95	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	0	51	with	Activity	25:32	arg1	Nano-Silver					101:111	Nano-Silver	101:111	Nano-Silver	101:111	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	0	52	theme	Film	56:59	arg1	Solution					61:68	Chitosan Composite Film Solution	37:68	Chitosan Composite Film Solution	37:68	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	2	53	theme	exposure	371:378	arg1	time					380:383	longer UV exposure time	361:383	longer UV exposure time	361:383	With longer UV exposure time, pathogen inhibition increased.					
35020918	8	54	theme	solution	1331:1338	arg1	induction					1283:1291	the UV light induction	1270:1291	the UV light induction of the CTS-TiO2-Ag nanocomposite film solution	1270:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	1	55	theme	film	255:258	arg1	solution					260:267	chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution	194:267	chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution	194:267	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	5	56	theme	120-h	691:695	arg1	period					704:709	a 120-h growth period	689:709	a 120-h growth period on mangoes under the same conditions	689:746	After a 120-h growth period on mangoes under the same conditions, the lesion diameters and proportion of infected mangoes reached 12.61 mm and 41.67%, respectively.					
35020918	2	57	theme	UV	368:369	arg1	time					380:383	longer UV exposure time	361:383	longer UV exposure time	361:383	With longer UV exposure time, pathogen inhibition increased.					
35020918	8	58	theme	CTS-TiO2-Ag	1300:1310	arg1	solution					1331:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	the CTS-TiO2-Ag nanocomposite film solution	1296:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	1	59	theme	solution	260:267	arg1	effect					184:189	the UV light-induced effect	163:189	the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii	163:295	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	1	59	theme	solution	260:267	arg1	mechanism					330:338	the underlying physiological mechanism	301:338	the underlying physiological mechanism of this effect	301:353	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	0	60	theme	Nano-Titanium	75:87	arg1	Dioxide					89:95	Nano-Titanium Dioxide	75:95	Nano-Titanium Dioxide	75:95	Photo-Induced Antifungal Activity of Chitosan Composite Film Solution with Nano-Titanium Dioxide and Nano-Silver.					
35020918	7	61	from	Malondialdehyde	1019:1033	arg1	cells					1089:1093	the P. steckii cells	1074:1093	the P. steckii cells	1074:1093	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	1	62	dep	ABSTRACT	114:121	arg1	conducted					138:146	conducted	138:146	was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect	134:353	ABSTRACT This study was conducted to investigate the UV light-induced effect of chitosan-titanium dioxide-silver (CTS-TiO2-Ag) nanocomposite film solution against Penicillium steckii and the underlying physiological mechanism of this effect.					
35020918	8	63	theme	light	1277:1281	arg1	induction					1283:1291	the UV light induction	1270:1291	the UV light induction of the CTS-TiO2-Ag nanocomposite film solution	1270:1338	These results indicate significant P. steckii inhibition by the UV light induction of the CTS-TiO2-Ag nanocomposite film solution.					
35020918	6	64	theme	material	1009:1016	arg1	extravasation					953:965	serious extravasation	945:965	serious extravasation of intracellular protein and nucleic acid material	945:1016	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35020918	7	65	theme	incubation	1198:1207	arg1	h					1193:1193	8 h	1191:1193	8 h of incubation	1191:1207	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	7	66	from	catalase	1036:1043	arg1	cells					1089:1093	the P. steckii cells	1074:1093	the P. steckii cells	1074:1093	Malondialdehyde, catalase, and superoxide dismutase in the P. steckii cells reached maximum concentrations (2.1106 μmol/mL, 44.06 U/mL, and 24.67 U/mL, respectively) after 8 h of incubation.					
35020918	4	67	theme	medium	621:626	arg1	conductivity					582:593	the conductivity	578:593	the conductivity of the P. steckii culture medium	578:626	However, when this treatment was followed by 8 h of storage, the conductivity of the P. steckii culture medium reached its highest level, at 713 microsiemens per cm.					
35020918	6	68	theme	acid	1004:1007	arg1	material					1009:1016	nucleic acid material	996:1016	nucleic acid material	996:1016	Because the P. steckii cell membrane was severely disrupted, its permeability increased, causing serious extravasation of intracellular protein and nucleic acid material.					
35565974	7	0	theme	HIUS	900:903	arg1	treatment					905:913	HIUS treatment	900:913	HIUS treatment	900:913	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	8	1	theme	dynamic	1072:1078	arg1	scattering					1086:1095	back dynamic light scattering	1067:1095	back dynamic light scattering	1067:1095	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	10	2	theme	HIUS	1427:1430	arg1	treatment					1432:1440	HIUS treatment	1427:1440	HIUS treatment	1427:1440	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	10	3	theme	treatment	1432:1440	arg1	use					1420:1422	the use	1416:1422	the use of HIUS treatment	1416:1440	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	0	4	from	Influence	4:12	arg1	Properties					51:60	Properties	51:60	Properties of Cellulose	51:73	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	5	5	theme	high-intensity	593:606	arg1	HIUS					625:628	HIUS	625:628	HIUS	625:628	The high-intensity ultrasonication (HIUS) was applied to reach further disintegration of cellulose fibers.					
35565974	5	5	theme	high-intensity	593:606	arg1	ultrasonication					608:622	The high-intensity ultrasonication	589:622	The high-intensity ultrasonication (HIUS)	589:629	The high-intensity ultrasonication (HIUS) was applied to reach further disintegration of cellulose fibers.					
35565974	10	6	theme	first	1313:1317	arg1	This					1300:1303	This	1300:1303	This	1300:1303	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	10	6	theme	first	1313:1317	arg1	time					1319:1322	the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment	1309:1440	the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment	1309:1440	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	9	7	theme	hop	1179:1181	arg1	source					1205:1210	a potential source	1193:1210	a potential source of cellulose	1193:1223	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	9	7	theme	hop	1179:1181	arg1	stems					1183:1187	the hop stems	1175:1187	the hop stems	1175:1187	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	4	8	theme	median	516:521	arg1	diameter					523:530	median diameter	516:530	median diameter of 6.7 nm obtained from atomic force microscopy imaging	516:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	8	9	theme	light	1080:1084	arg1	scattering					1086:1095	back dynamic light scattering	1067:1095	back dynamic light scattering	1067:1095	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	2	10	contain	contain	282:288	arg1	stems					276:280	Hop stems	272:280	Hop stems	272:280	Hop stems contain up to 29% of cellulose.					
35565974	2	10	contain	contain	282:288	arg2	%					298:298	up to 29%	290:298	up to 29% of cellulose	290:311	Hop stems contain up to 29% of cellulose.					
35565974	2	10	contain	contain	282:288	arg2	cellulose					303:311	cellulose	303:311	cellulose	303:311	Hop stems contain up to 29% of cellulose.					
35565974	8	11	dep	scattering	1086:1095	arg1	methods					1131:1137	methods	1131:1137	methods	1131:1137	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	6	12	theme	even	767:770	arg1	degree					760:765	crystallinity degree	746:765	crystallinity degree even up to 60%	746:780	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	1	13	theme	hop	214:216	arg1	cones					218:222	hop cones	214:222	hop cones production	214:233	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	0	14	theme	Hop	93:95	arg1	Stems					97:101	the Hop Stems	89:101	the Hop Stems	89:101	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	0	14	theme	Hop	93:95	arg1	Byproduct					108:116	the Byproduct	104:116	the Byproduct of the Hop Cones Production	104:144	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	7	15	theme	intermolecular	933:946	arg1	bonds					957:961	intermolecular hydrogen bonds	933:961	intermolecular hydrogen bonds	933:961	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	7	16	theme	FTIR	874:877	arg1	spectra					880:886	spectroscopy (FTIR) spectra	860:886	spectroscopy (FTIR) spectra	860:886	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	9	17	theme	HIUS	1284:1287	arg1	treatment					1289:1297	HIUS treatment	1284:1297	HIUS treatment	1284:1297	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	1	18	theme	cones	218:222	arg1	production					224:233	hop cones production	214:233	hop cones production	214:233	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	5	19	theme	fibers	688:693	arg1	disintegration					660:673	further disintegration	652:673	further disintegration of cellulose fibers	652:693	The high-intensity ultrasonication (HIUS) was applied to reach further disintegration of cellulose fibers.					
35565974	6	20	theme	crystallinity	746:758	arg1	degree					760:765	crystallinity degree	746:765	crystallinity degree even up to 60%	746:780	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	10	21	theme	cellulose	1351:1359	arg1	properties					1333:1342	the properties	1329:1342	the properties of hop cellulose	1329:1359	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	3	22	theme	thermochemical	364:377	arg1	treatment					379:387	the thermochemical treatment	360:387	the thermochemical treatment	360:387	The cellulose isolation was conducted through the thermochemical treatment.					
35565974	9	23	theme	Obtained	1140:1147	arg1	evidence					1161:1168	evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment	1161:1297	evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment	1161:1297	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	9	23	theme	Obtained	1140:1147	arg1	results					1149:1155	Obtained results	1140:1155	Obtained results	1140:1155	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	7	24	theme	spectroscopy	860:871	arg1	spectra					880:886	spectroscopy (FTIR) spectra	860:886	spectroscopy (FTIR) spectra	860:886	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	2	25	dep	29	296:297	arg1	to					293:294	to	293:294	to	293:294	Hop stems contain up to 29% of cellulose.					
35565974	8	26	theme	HIUS	1020:1023	arg1	treatment					1025:1033	HIUS treatment	1020:1033	HIUS treatment	1020:1033	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	8	27	theme	Doppler	1107:1113	arg1	electrophoresis					1115:1129	laser Doppler electrophoresis	1101:1129	laser Doppler electrophoresis	1101:1129	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	9	28	theme	potential	1195:1203	arg1	source					1205:1210	a potential source	1193:1210	a potential source of cellulose	1193:1223	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	9	28	theme	potential	1195:1203	arg1	stems					1183:1187	the hop stems	1175:1187	the hop stems	1175:1187	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	8	29	theme	dispersions	991:1001	arg1	stability					968:976	The stability	964:976	The stability of cellulose dispersions versus length of HIUS treatment	964:1033	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	4	30	theme	X-ray	494:498	arg1	diffraction					500:510	X-ray diffraction	494:510	X-ray diffraction	494:510	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	8	31	theme	treatment	1025:1033	arg1	length					1010:1015	length	1010:1015	length of HIUS treatment	1010:1033	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	2	32	theme	cellulose	303:311	arg1	cellulose					303:311	cellulose	303:311	cellulose	303:311	Hop stems contain up to 29% of cellulose.					
35565974	2	32	theme	cellulose	303:311	arg1	%					298:298	up to 29%	290:298	up to 29% of cellulose	290:311	Hop stems contain up to 29% of cellulose.					
35565974	5	33	theme	further	652:658	arg1	disintegration					660:673	further disintegration	652:673	further disintegration of cellulose fibers	652:693	The high-intensity ultrasonication (HIUS) was applied to reach further disintegration of cellulose fibers.					
35565974	1	34	theme	production	224:233	arg1	stems					192:196	the hop stems	184:196	the hop stems	184:196	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	1	34	theme	production	224:233	arg1	byproduct					201:209	a byproduct	199:209	a byproduct of hop cones production	199:233	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	8	35	theme	cellulose	981:989	arg1	dispersions					991:1001	cellulose dispersions	981:1001	cellulose dispersions	981:1001	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	6	36	from	decrease	786:793	arg1	degree					760:765	crystallinity degree	746:765	crystallinity degree even up to 60%	746:780	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	6	36	from	decrease	786:793	arg1	diameter					808:815	the fiber diameter	798:815	the fiber diameter up to 4 nm	798:826	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	1	37	theme	work	164:167	arg1	goal					151:154	The goal	147:154	The goal of this work	147:167	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	0	38	theme	High-Intensity	17:30	arg1	Ultrasonication					32:46	High-Intensity Ultrasonication	17:46	High-Intensity Ultrasonication	17:46	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	8	39	theme	length	1010:1015	arg1	stability					968:976	The stability	964:976	The stability of cellulose dispersions versus length of HIUS treatment	964:1033	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	7	40	dep	Fourier	833:839	arg1	transform					841:849	transform	841:849	transform infrared spectroscopy (FTIR) spectra	841:886	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	9	41	theme	stable	1259:1264	arg1	dispersions					1266:1276	stable dispersions	1259:1276	stable dispersions	1259:1276	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	6	42	theme	fiber	802:806	arg1	diameter					808:815	the fiber diameter	798:815	the fiber diameter up to 4 nm	798:826	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	4	43	theme	force	563:567	arg1	microscopy					569:578	atomic force microscopy	556:578	atomic force microscopy imaging	556:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	7	44	from	changes	922:928	arg1	bonds					957:961	intermolecular hydrogen bonds	933:961	intermolecular hydrogen bonds	933:961	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	0	45	theme	Hop	125:127	arg1	Production					135:144	the Hop Cones Production	121:144	the Hop Cones Production	121:144	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	6	46	dep	even	767:770	arg1	%					780:780	up to 60%	772:780	up to 60%	772:780	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	0	47	theme	Ultrasonication	32:46	arg1	Influence					4:12	The Influence	0:12	The Influence of High-Intensity Ultrasonication on Properties of Cellulose	0:73	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	4	48	theme	crystallinity	459:471	arg1	degree					473:478	crystallinity degree	459:478	crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging	459:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	6	49	dep	nm	825:826	arg1	4					823:823	4	823:823	4	823:823	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	6	50	dep	4	823:823	arg1	to					820:821	to	820:821	to	820:821	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	4	51	theme	degree	473:478	arg1	degree					473:478	crystallinity degree	459:478	crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging	459:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	4	51	theme	degree	473:478	arg1	%					454:454	67%	452:454	67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging	452:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	3	52	theme	cellulose	318:326	arg1	isolation					328:336	The cellulose isolation	314:336	The cellulose isolation	314:336	The cellulose isolation was conducted through the thermochemical treatment.					
35565974	1	53	theme	potential	241:249	arg1	source					251:256	a potential source	239:256	a potential source of cellulose	239:269	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	1	53	theme	potential	241:249	arg1	stems					192:196	the hop stems	184:196	the hop stems	184:196	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	0	54	theme	Production	135:144	arg1	Stems					97:101	the Hop Stems	89:101	the Hop Stems	89:101	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	0	54	theme	Production	135:144	arg1	Byproduct					108:116	the Byproduct	104:116	the Byproduct of the Hop Cones Production	104:144	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	4	55	theme	high-speed	396:405	arg1	blending					407:414	high-speed blending	396:414	high-speed blending	396:414	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	6	56	theme	HIUS	707:710	arg1	treatment					712:720	The longer HIUS treatment	696:720	The longer HIUS treatment	696:720	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	0	57	theme	Cones	129:133	arg1	Production					135:144	the Hop Cones Production	121:144	the Hop Cones Production	121:144	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	6	58	dep	60	778:779	arg1	to					775:776	to	775:776	to	775:776	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	6	59	theme	longer	700:705	arg1	treatment					712:720	The longer HIUS treatment	696:720	The longer HIUS treatment	696:720	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	10	60	theme	hop	1347:1349	arg1	cellulose					1351:1359	hop cellulose	1347:1359	hop cellulose	1347:1359	This was the first time that the properties of hop cellulose have been described so extensively and in detail after the use of HIUS treatment.					
35565974	1	61	theme	cellulose	261:269	arg1	source					251:256	a potential source	239:256	a potential source of cellulose	239:269	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	1	61	theme	cellulose	261:269	arg1	stems					192:196	the hop stems	184:196	the hop stems	184:196	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	7	62	theme	hydrogen	948:955	arg1	bonds					957:961	intermolecular hydrogen bonds	933:961	intermolecular hydrogen bonds	933:961	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	2	63	theme	Hop	272:274	arg1	stems					276:280	Hop stems	272:280	Hop stems	272:280	Hop stems contain up to 29% of cellulose.					
35565974	1	64	theme	hop	188:190	arg1	source					251:256	a potential source	239:256	a potential source of cellulose	239:269	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	1	64	theme	hop	188:190	arg1	stems					192:196	the hop stems	184:196	the hop stems	184:196	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	1	64	theme	hop	188:190	arg1	byproduct					201:209	a byproduct	199:209	a byproduct of hop cones production	199:233	The goal of this work is to evaluate the hop stems, a byproduct of hop cones production, as a potential source of cellulose.					
35565974	8	65	theme	laser	1101:1105	arg1	electrophoresis					1115:1129	laser Doppler electrophoresis	1101:1129	laser Doppler electrophoresis	1101:1129	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	4	66	theme	nm	539:540	arg1	diffraction					500:510	X-ray diffraction	494:510	X-ray diffraction	494:510	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	4	66	theme	nm	539:540	arg1	diameter					523:530	median diameter	516:530	median diameter of 6.7 nm obtained from atomic force microscopy imaging	516:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	6	67	from	decrease	734:741	arg1	degree					760:765	crystallinity degree	746:765	crystallinity degree even up to 60%	746:780	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	6	67	from	decrease	734:741	arg1	diameter					808:815	the fiber diameter	798:815	the fiber diameter up to 4 nm	798:826	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	8	68	with	days	1057:1060	arg1	electrophoresis					1115:1129	laser Doppler electrophoresis	1101:1129	laser Doppler electrophoresis	1101:1129	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	8	68	with	days	1057:1060	arg1	scattering					1086:1095	back dynamic light scattering	1067:1095	back dynamic light scattering	1067:1095	The stability of cellulose dispersions versus length of HIUS treatment was monitored over 14 days with back dynamic light scattering and laser Doppler electrophoresis methods.					
35565974	4	69	theme	atomic	556:561	arg1	microscopy					569:578	atomic force microscopy	556:578	atomic force microscopy imaging	556:586	After high-speed blending, the cellulose was characterized by 67% of crystallinity degree obtained from X-ray diffraction and median diameter of 6.7 nm obtained from atomic force microscopy imaging.					
35565974	0	70	theme	Cellulose	65:73	arg1	Properties					51:60	Properties	51:60	Properties of Cellulose	51:73	The Influence of High-Intensity Ultrasonication on Properties of Cellulose Produced from the Hop Stems, the Byproduct of the Hop Cones Production.					
35565974	9	71	theme	cellulose	1215:1223	arg1	source					1205:1210	a potential source	1193:1210	a potential source of cellulose	1193:1223	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	9	71	theme	cellulose	1215:1223	arg1	stems					1183:1187	the hop stems	1175:1187	the hop stems	1175:1187	Obtained results are evidence that the hop stems are a potential source of cellulose and that it is possible to obtain stable dispersions after HIUS treatment.					
35565974	6	72	dep	diameter	808:815	arg1	nm					825:826	nm	825:826	nm	825:826	The longer HIUS treatment resulted in decrease in crystallinity degree even up to 60% and decrease in the fiber diameter up to 4 nm.					
35565974	7	73	dep	transform	841:849	arg1	infrared					851:858	infrared	851:858	transform infrared spectroscopy (FTIR) spectra	841:886	The Fourier transform infrared spectroscopy (FTIR) spectra showed that HIUS treatment led to changes in intermolecular hydrogen bonds.					
35565974	5	74	theme	cellulose	678:686	arg1	fibers					688:693	cellulose fibers	678:693	cellulose fibers	678:693	The high-intensity ultrasonication (HIUS) was applied to reach further disintegration of cellulose fibers.					
35989009	0	0	theme	resistance	98:107	arg1	performance					109:119	thermally stable and ultraviolet resistance performance	65:119	thermally stable and ultraviolet resistance performance	65:119	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	5	1	theme	water	814:818	arg1	solubility					820:829	water solubility	814:829	water solubility	814:829	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	1	2	with	film	180:183	arg1	performance					195:205	good performance	190:205	good performance	190:205	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	9	3	theme	guiding	1268:1274	arg1	significance					1276:1287	certain guiding significance	1260:1287	certain guiding significance for polysaccharide-based mulch film	1260:1323	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	0	4	theme	ultraviolet	86:96	arg1	performance					109:119	thermally stable and ultraviolet resistance performance	65:119	thermally stable and ultraviolet resistance performance	65:119	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	3	5	theme	mechanical	541:550	arg1	properties					552:561	mechanical properties	541:561	mechanical properties	541:561	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	1	6	theme	humic	291:295	arg1	GCS					318:320	GCS	318:320	GCS	318:320	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	1	6	theme	humic	291:295	arg1	complexes					307:315	humic acid/urea complexes	291:315	humic acid/urea complexes (GCS)	291:321	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	5	7	theme	glutaraldehyde	760:773	arg1	crosslinking					775:786	glutaraldehyde crosslinking	760:786	glutaraldehyde crosslinking	760:786	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	9	8	theme	polysaccharide-based	1293:1312	arg1	film					1320:1323	polysaccharide-based mulch film	1293:1323	polysaccharide-based mulch film	1293:1323	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	1	9	theme	acid/urea	297:305	arg1	GCS					318:320	GCS	318:320	GCS	318:320	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	1	9	theme	acid/urea	297:305	arg1	complexes					307:315	humic acid/urea complexes	291:315	humic acid/urea complexes (GCS)	291:321	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	6	10	theme	ultraviolet	936:946	arg1	resistance					948:957	ultraviolet resistance	936:957	ultraviolet resistance	936:957	Meanwhile, the thermostability and ultraviolet resistance were improved.					
35989009	8	11	theme	excellent	1126:1134	arg1	compatibility					1136:1148	excellent compatibility	1126:1148	excellent compatibility	1126:1148	Morphological analyses present film has excellent compatibility.					
35989009	7	12	theme	X-ray	1004:1008	arg1	diffractometry					1010:1023	X-ray diffractometry	1004:1023	X-ray diffractometry	1004:1023	The infrared spectroscopy and X-ray diffractometry demonstrated the successfully crosslinked by glutaraldehyde.					
35989009	8	13	dep	present	1109:1115	arg1	has					1122:1124	has	1122:1124	present film has excellent compatibility	1109:1148	Morphological analyses present film has excellent compatibility.					
35989009	4	14	theme	tensile	627:633	arg1	strength					635:642	tensile strength	627:642	tensile strength	627:642	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	9	15	theme	GCS-HA/CE	1164:1172	arg1	film					1174:1177	GCS-HA/CE film	1164:1177	GCS-HA/CE film	1164:1177	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	9	16	theme	mulch	1314:1318	arg1	film					1320:1323	polysaccharide-based mulch film	1293:1323	polysaccharide-based mulch film	1293:1323	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	4	17	from	%	709:709	arg1	state					718:722	dry state	714:722	dry state	714:722	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	1	18	theme	good	190:193	arg1	performance					195:205	good performance	190:205	good performance	190:205	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	5	19	theme	moisture	796:803	arg1	content					805:811	moisture content	796:811	moisture content	796:811	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	2	20	with	endowed	442:448	arg1	property					468:475	the improved property	455:475	the improved property	455:475	By flow-coating with GCS to construct hierarchical networks, GCS-HA/CE film is endowed with the improved property.					
35989009	8	21	theme	Morphological	1086:1098	arg1	analyses					1100:1107	Morphological analyses	1086:1107	Morphological analyses	1086:1107	Morphological analyses present film has excellent compatibility.					
35989009	9	22	theme	good	1185:1188	arg1	preservation					1195:1206	good heat preservation	1185:1206	good heat preservation	1185:1206	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	2	23	theme	hierarchical	401:412	arg1	networks					414:421	hierarchical networks	401:421	hierarchical networks	401:421	By flow-coating with GCS to construct hierarchical networks, GCS-HA/CE film is endowed with the improved property.					
35989009	2	24	theme	improved	459:466	arg1	property					468:475	the improved property	455:475	the improved property	455:475	By flow-coating with GCS to construct hierarchical networks, GCS-HA/CE film is endowed with the improved property.					
35989009	4	25	from	53.97 MPa	689:697	arg1	state					718:722	dry state	714:722	dry state	714:722	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	0	26	theme	polysaccharide-based	28:47	arg1	film					55:58	hydrophobic polysaccharide-based mulch film	16:58	hydrophobic polysaccharide-based mulch film	16:58	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	3	27	from	concentrations	523:536	arg1	properties					552:561	mechanical properties	541:561	mechanical properties	541:561	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	3	28	theme	optimum	585:591	arg1	concentration					593:605	the optimum concentration	581:605	the optimum concentration	581:605	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	1	29	theme	plastic	221:227	arg1	mulch					229:233	plastic mulch	221:233	plastic mulch	221:233	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	0	30	theme	hydrophobic	16:26	arg1	film					55:58	hydrophobic polysaccharide-based mulch film	16:58	hydrophobic polysaccharide-based mulch film	16:58	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	4	31	dep	strength	635:642	arg1	The					623:625	The	623:625	The	623:625	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	4	32	theme	film	672:675	arg1	elongation					648:657	elongation	648:657	elongation	648:657	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	4	32	theme	film	672:675	arg1	strength					635:642	tensile strength	627:642	tensile strength	627:642	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	3	33	with	influences	482:491	arg1	concentrations					523:536	different concentrations	513:536	different concentrations on mechanical properties	513:561	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	9	34	theme	aging	1209:1213	arg1	resistance					1215:1224	aging resistance	1209:1224	aging resistance	1209:1224	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	0	35	theme	mulch	49:53	arg1	film					55:58	hydrophobic polysaccharide-based mulch film	16:58	hydrophobic polysaccharide-based mulch film	16:58	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	1	36	theme	cellulose/humic	328:342	arg1	acid					344:347	cellulose/humic acid	328:347	cellulose/humic acid (HA/CE) film	328:360	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	1	36	theme	cellulose/humic	328:342	arg1	HA/CE					350:354	HA/CE	350:354	HA/CE	350:354	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	9	37	theme	heat	1190:1193	arg1	preservation					1195:1206	good heat preservation	1185:1206	good heat preservation	1185:1206	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	4	38	theme	GCS-HA/CE	662:670	arg1	film					672:675	GCS-HA/CE film	662:675	GCS-HA/CE film	662:675	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	2	39	theme	GCS-HA/CE	424:432	arg1	film					434:437	GCS-HA/CE film	424:437	GCS-HA/CE film	424:437	By flow-coating with GCS to construct hierarchical networks, GCS-HA/CE film is endowed with the improved property.					
35989009	5	40	theme	water	836:840	arg1	permeability					848:859	water vapor permeability	836:859	water vapor permeability	836:859	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	1	41	theme	acid	344:347	arg1	film					357:360	cellulose/humic acid (HA/CE) film	328:360	cellulose/humic acid (HA/CE) film	328:360	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	3	42	theme	different	513:521	arg1	concentrations					523:536	different concentrations	513:536	different concentrations on mechanical properties	513:561	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	5	43	theme	vapor	842:846	arg1	permeability					848:859	water vapor permeability	836:859	water vapor permeability	836:859	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	7	44	theme	infrared	978:985	arg1	spectroscopy					987:998	The infrared spectroscopy	974:998	The infrared spectroscopy	974:998	The infrared spectroscopy and X-ray diffractometry demonstrated the successfully crosslinked by glutaraldehyde.					
35989009	0	45	with	Sustainable	0:10	arg1	performance					109:119	thermally stable and ultraviolet resistance performance	65:119	thermally stable and ultraviolet resistance performance	65:119	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	3	46	theme	composition	496:506	arg1	influences					482:491	The influences	478:491	The influences of composition with different concentrations on mechanical properties	478:561	The influences of composition with different concentrations on mechanical properties were studied, and the optimum concentration was determined.					
35989009	9	47	theme	certain	1260:1266	arg1	significance					1276:1287	certain guiding significance	1260:1287	certain guiding significance for polysaccharide-based mulch film	1260:1323	In addition, GCS-HA/CE film shows good heat preservation, aging resistance, and biodegradability, indicating certain guiding significance for polysaccharide-based mulch film.					
35989009	4	48	theme	dry	714:716	arg1	state					718:722	dry state	714:722	dry state	714:722	The tensile strength and elongation of GCS-HA/CE film could reach 53.97 MPa and 12.86 % in dry state, respectively.					
35989009	1	49	theme	glutaraldehyde	250:263	arg1	chitosan					278:285	the glutaraldehyde crosslinking chitosan	246:285	the glutaraldehyde crosslinking chitosan	246:285	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	5	50	theme	contact	876:882	arg1	94.025°					891:897	94.025°	891:897	94.025°	891:897	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	5	50	theme	contact	876:882	arg1	angle					884:888	contact angle	876:888	contact angle (94.025°)	876:898	Results suggest that glutaraldehyde crosslinking reduces moisture content, water solubility, and water vapor permeability, but increases contact angle (94.025°).					
35989009	1	51	theme	polysaccharide-based	153:172	arg1	film					180:183	a polysaccharide-based mulch film	151:183	a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film	151:360	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	1	52	theme	crosslinking	265:276	arg1	chitosan					278:285	the glutaraldehyde crosslinking chitosan	246:285	the glutaraldehyde crosslinking chitosan	246:285	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
35989009	0	53	theme	stable	75:80	arg1	performance					109:119	thermally stable and ultraviolet resistance performance	65:119	thermally stable and ultraviolet resistance performance	65:119	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	0	54	with	film	55:58	arg1	performance					109:119	thermally stable and ultraviolet resistance performance	65:119	thermally stable and ultraviolet resistance performance	65:119	Sustainable and hydrophobic polysaccharide-based mulch film with thermally stable and ultraviolet resistance performance.					
35989009	1	55	theme	mulch	174:178	arg1	film					180:183	a polysaccharide-based mulch film	151:183	a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film	151:360	This work aimed to construct a polysaccharide-based mulch film with good performance for replacing plastic mulch by coating the glutaraldehyde crosslinking chitosan and humic acid/urea complexes (GCS) into cellulose/humic acid (HA/CE) film.					
36113599	8	0	theme	NiFe2O4	1012:1018	arg1	composite					1028:1036	NiFe2O4@SEH-CSB composite	1012:1036	NiFe2O4@SEH-CSB composite	1012:1036	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	9	1	theme	@	1245:1245	arg1	composite					1254:1262	NiFe2O4@SEH-CSB composite	1238:1262	NiFe2O4@SEH-CSB composite	1238:1262	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	7	2	theme	NiFe2O4	899:905	arg1	SEH-CSB					907:913	NiFe2O4@SEH-CSB	899:913	NiFe2O4@SEH-CSB towards Cr(VI)	899:928	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	1	3	theme	organic-inorganic	143:159	arg1	composite					161:169	a novel magnetic organic-inorganic composite	126:169	a novel magnetic organic-inorganic composite	126:169	In this study, a novel magnetic organic-inorganic composite was fabricated.					
36113599	6	4	attach	removal	727:733	arg3	SEH-CSB					756:762	NiFe2O4@SEH-CSB	748:762	NiFe2O4@SEH-CSB	748:762	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	6	4	attach	removal	727:733	arg2	Cr					738:739	Cr	738:739	Cr(VI)	738:743	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	7	5	theme	adsorption	876:885	arg1	373.61 mg/g					946:956	373.61 mg/g	946:956	373.61 mg/g	946:956	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	7	5	theme	adsorption	876:885	arg1	capacity					887:894	the maximum adsorption capacity	864:894	the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI)	864:928	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	3	6	theme	magnetic	509:516	arg1	SEH-CSB					558:564	NiFe2O4@SEH-CSB	550:564	NiFe2O4@SEH-CSB	550:564	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	3	6	theme	magnetic	509:516	arg1	composite					539:547	the magnetic Chitosan-Schiff-base composite	505:547	the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	505:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	8	7	theme	SEH-CSB	1020:1026	arg1	composite					1028:1036	NiFe2O4@SEH-CSB composite	1012:1036	NiFe2O4@SEH-CSB composite	1012:1036	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	6	8	theme	kinetics	815:822	arg1	model					824:828	pseudo-second order kinetics model	795:828	pseudo-second order kinetics model	795:828	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	3	9	theme	Chitosan-Schiff-base	518:537	arg1	SEH-CSB					558:564	NiFe2O4@SEH-CSB	550:564	NiFe2O4@SEH-CSB	550:564	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	3	9	theme	Chitosan-Schiff-base	518:537	arg1	composite					539:547	the magnetic Chitosan-Schiff-base composite	505:547	the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	505:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	3	10	theme	@	557:557	arg1	SEH-CSB					558:564	NiFe2O4@SEH-CSB	550:564	NiFe2O4@SEH-CSB	550:564	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	3	10	theme	@	557:557	arg1	composite					539:547	the magnetic Chitosan-Schiff-base composite	505:547	the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	505:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	9	11	theme	magnetic	1194:1201	arg1	property					1203:1210	The magnetic property	1190:1210	The magnetic property	1190:1210	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	8	12	theme	@	1019:1019	arg1	composite					1028:1036	NiFe2O4@SEH-CSB composite	1012:1036	NiFe2O4@SEH-CSB composite	1012:1036	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	6	13	theme	order	809:813	arg1	kinetics					815:822	pseudo-second order kinetics	795:822	pseudo-second order kinetics model	795:828	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	6	14	theme	pseudo-second	795:807	arg1	kinetics					815:822	pseudo-second order kinetics	795:822	pseudo-second order kinetics model	795:828	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	7	15	theme	maximum	868:874	arg1	373.61 mg/g					946:956	373.61 mg/g	946:956	373.61 mg/g	946:956	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	7	15	theme	maximum	868:874	arg1	capacity					887:894	the maximum adsorption capacity	864:894	the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI)	864:928	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	0	16	dep	removal	102:108	arg1	VI					98:99	VI	98:99	VI	98:99	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.					
36113599	7	17	dep	Cr	923:924	arg1	VI					926:927	VI	926:927	VI	926:927	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	8	18	theme	ion-exchange	1116:1127	arg1	domination					1052:1061	the domination	1048:1061	the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways	1048:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	5	19	theme	Cr	715:716	arg1	removal					704:710	the removal	700:710	the removal of Cr(VI)	700:720	Results clarified that SHE played a crucial role in the removal of Cr(VI).					
36113599	9	20	theme	easy	1220:1223	arg1	recycling					1225:1233	easy recycling	1220:1233	easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles	1220:1290	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	6	21	theme	Cr	738:739	arg1	removal					727:733	The removal	723:733	The removal of Cr(VI) on NiFe2O4@SEH-CSB	723:762	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	3	22	theme	NiFe2O4	550:556	arg1	SEH-CSB					558:564	NiFe2O4@SEH-CSB	550:564	NiFe2O4@SEH-CSB	550:564	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	3	22	theme	NiFe2O4	550:556	arg1	composite					539:547	the magnetic Chitosan-Schiff-base composite	505:547	the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	505:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	6	23	dep	Cr	738:739	arg1	VI					741:742	VI	741:742	VI	741:742	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	9	24	theme	SEH-CSB	1246:1252	arg1	composite					1254:1262	NiFe2O4@SEH-CSB composite	1238:1262	NiFe2O4@SEH-CSB composite	1238:1262	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	8	25	theme	surface	1130:1136	arg1	complexation					1138:1149	surface complexation	1130:1149	surface complexation	1130:1149	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	26	dep	Cr	1002:1003	arg1	VI					1005:1006	VI	1005:1006	VI	1005:1006	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	27	theme	complexation	1138:1149	arg1	domination					1052:1061	the domination	1048:1061	the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways	1048:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	0	28	theme	new	15:17	arg1	Sulfacetamide-Ethylacetoacetate					28:58	a new magnetic Sulfacetamide-Ethylacetoacetate	13:58	a new magnetic Sulfacetamide-Ethylacetoacetate	13:58	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.					
36113599	9	29	theme	NiFe2O4	1238:1244	arg1	composite					1254:1262	NiFe2O4@SEH-CSB composite	1238:1262	NiFe2O4@SEH-CSB composite	1238:1262	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	2	30	dep	capable	368:374	arg1	sites					357:361	active sites	350:361	active sites that capable of forming coordinate covalent bonds with Cr(VI)	350:423	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	31	used	used	237:240	arg2	ethylacetoacetae					215:230	ethylacetoacetae	215:230	ethylacetoacetae	215:230	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	31	used	used	237:240	arg2	sulfacetamide					197:209	sulfacetamide	197:209	sulfacetamide	197:209	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	31	used	used	237:240	arg2	Chitosan					187:194	Chitosan	187:194	Chitosan	187:194	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	3	32	theme	formed	467:472	arg1	SHE-CSB					474:480	the formed SHE-CSB	463:480	the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	463:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	7	33	theme	SEH-CSB	907:913	arg1	373.61 mg/g					946:956	373.61 mg/g	946:956	373.61 mg/g	946:956	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	7	33	theme	SEH-CSB	907:913	arg1	capacity					887:894	the maximum adsorption capacity	864:894	the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI)	864:928	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	4	34	theme	@	575:575	arg1	SEH-CSB					576:582	NiFe2O4@SEH-CSB	568:582	NiFe2O4@SEH-CSB	568:582	NiFe2O4@SEH-CSB was characterized using FTIR, zeta potential, SEM, VSM and XPS.					
36113599	5	35	theme	crucial	684:690	arg1	role					692:695	a crucial role	682:695	a crucial role	682:695	Results clarified that SHE played a crucial role in the removal of Cr(VI).					
36113599	3	36	theme	SHE-CSB	474:480	arg1	modification					447:458	modification	447:458	modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB)	447:565	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	0	37	theme	Sulfacetamide-Ethylacetoacetate	28:58	arg1	Synthesis					0:8	Synthesis	0:8	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate	0:58	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.					
36113599	4	38	theme	NiFe2O4	568:574	arg1	SEH-CSB					576:582	NiFe2O4@SEH-CSB	568:582	NiFe2O4@SEH-CSB	568:582	NiFe2O4@SEH-CSB was characterized using FTIR, zeta potential, SEM, VSM and XPS.					
36113599	8	39	theme	plausible	963:971	arg1	mechanism					973:981	The plausible mechanism	959:981	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite	959:1036	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	40	theme	bond	1175:1178	arg1	pathways					1180:1187	coordinate-covalent bond pathways	1155:1187	coordinate-covalent bond pathways	1155:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	0	41	theme	magnetic	19:26	arg1	Sulfacetamide-Ethylacetoacetate					28:58	a new magnetic Sulfacetamide-Ethylacetoacetate	13:58	a new magnetic Sulfacetamide-Ethylacetoacetate	13:58	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.					
36113599	9	42	theme	composite	1254:1262	arg1	recycling					1225:1233	easy recycling	1220:1233	easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles	1220:1290	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	3	43	with	SHE-CSB	474:480	arg1	NiFe2O4					487:493	NiFe2O4	487:493	NiFe2O4	487:493	This was followed by modification of the formed SHE-CSB with NiFe2O4 to obtain the magnetic Chitosan-Schiff-base composite (NiFe2O4@SEH-CSB).					
36113599	8	44	theme	coulombic	1066:1074	arg1	interaction					1076:1086	coulombic interaction	1066:1086	coulombic interaction	1066:1086	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	45	theme	coordinate-covalent	1155:1173	arg1	pathways					1180:1187	coordinate-covalent bond pathways	1155:1187	coordinate-covalent bond pathways	1155:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	46	theme	complexation	1102:1113	arg1	domination					1052:1061	the domination	1048:1061	the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways	1048:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	47	theme	interaction	1076:1086	arg1	domination					1052:1061	the domination	1048:1061	the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways	1048:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	8	48	theme	outer-sphere	1089:1100	arg1	complexation					1102:1113	outer-sphere complexation	1089:1113	outer-sphere complexation	1089:1113	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	5	49	dep	Cr	715:716	arg1	VI					718:719	VI	718:719	VI	718:719	Results clarified that SHE played a crucial role in the removal of Cr(VI).					
36113599	1	50	theme	magnetic	134:141	arg1	composite					161:169	a novel magnetic organic-inorganic composite	126:169	a novel magnetic organic-inorganic composite	126:169	In this study, a novel magnetic organic-inorganic composite was fabricated.					
36113599	8	51	theme	pathways	1180:1187	arg1	domination					1052:1061	the domination	1048:1061	the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways	1048:1187	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	9	52	theme	sequential	1274:1283	arg1	cycles					1285:1290	seven sequential cycles	1268:1290	seven sequential cycles	1268:1290	The magnetic property enabled easy recycling of NiFe2O4@SEH-CSB composite for seven sequential cycles.					
36113599	1	53	theme	novel	128:132	arg1	composite					161:169	a novel magnetic organic-inorganic composite	126:169	a novel magnetic organic-inorganic composite	126:169	In this study, a novel magnetic organic-inorganic composite was fabricated.					
36113599	2	54	theme	hydrazone-chitosan	291:308	arg1	SEH-CSB					323:329	SEH-CSB	323:329	SEH-CSB	323:329	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	54	theme	hydrazone-chitosan	291:308	arg1	Schiff-base					310:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base	253:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB)	253:330	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	55	theme	sites	357:361	arg1	variety					339:345	a variety	337:345	a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI)	337:423	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	55	theme	sites	357:361	arg1	sites					357:361	active sites	350:361	active sites that capable of forming coordinate covalent bonds with Cr(VI)	350:423	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	8	56	theme	Cr	1002:1003	arg1	removal					991:997	the removal	987:997	the removal of Cr(VI) by NiFe2O4@SEH-CSB composite	987:1036	The plausible mechanism for the removal of Cr(VI) by NiFe2O4@SEH-CSB composite suggested the domination of coulombic interaction, outer-sphere complexation, ion-exchange, surface complexation and coordinate-covalent bond pathways.					
36113599	6	57	theme	@	755:755	arg1	SEH-CSB					756:762	NiFe2O4@SEH-CSB	748:762	NiFe2O4@SEH-CSB	748:762	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	2	58	theme	Sulfacetamide-Ethylacetoacetate	259:289	arg1	SEH-CSB					323:329	SEH-CSB	323:329	SEH-CSB	323:329	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	58	theme	Sulfacetamide-Ethylacetoacetate	259:289	arg1	Schiff-base					310:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base	253:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB)	253:330	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	7	59	theme	@	906:906	arg1	SEH-CSB					907:913	NiFe2O4@SEH-CSB	899:913	NiFe2O4@SEH-CSB towards Cr(VI)	899:928	Besides, the maximum adsorption capacity of NiFe2O4@SEH-CSB towards Cr(VI) was found to be 373.61 mg/g.					
36113599	2	60	theme	active	350:355	arg1	sites					357:361	active sites	350:361	active sites that capable of forming coordinate covalent bonds with Cr(VI)	350:423	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	0	61	theme	Cr	95:96	arg1	removal					102:108	Cr(VI) removal	95:108	Cr(VI) removal	95:108	Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.					
36113599	6	62	theme	NiFe2O4	748:754	arg1	SEH-CSB					756:762	NiFe2O4@SEH-CSB	748:762	NiFe2O4@SEH-CSB	748:762	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	2	63	theme	new	255:257	arg1	SEH-CSB					323:329	SEH-CSB	323:329	SEH-CSB	323:329	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	63	theme	new	255:257	arg1	Schiff-base					310:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base	253:320	a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB)	253:330	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	6	64	from	removal	727:733	arg1	SEH-CSB					756:762	NiFe2O4@SEH-CSB	748:762	NiFe2O4@SEH-CSB	748:762	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	2	65	theme	covalent	398:405	arg1	bonds					407:411	coordinate covalent bonds	387:411	coordinate covalent bonds	387:411	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	6	66	theme	Freundlich	834:843	arg1	isotherm					845:852	Freundlich isotherm	834:852	Freundlich isotherm	834:852	The removal of Cr(VI) on NiFe2O4@SEH-CSB was found to be more fitted to pseudo-second order kinetics model and Freundlich isotherm.					
36113599	2	67	dep	Cr	418:419	arg1	VI					421:422	VI	421:422	VI	421:422	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	2	68	theme	coordinate	387:396	arg1	bonds					407:411	coordinate covalent bonds	387:411	coordinate covalent bonds	387:411	Chitosan, sulfacetamide and ethylacetoacetae were used to prepare a new Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base (SEH-CSB) with a variety of active sites that capable of forming coordinate covalent bonds with Cr(VI).					
36113599	4	69	theme	zeta	614:617	arg1	potential					619:627	zeta potential	614:627	zeta potential	614:627	NiFe2O4@SEH-CSB was characterized using FTIR, zeta potential, SEM, VSM and XPS.					
37127202	6	0	theme	electrochemical	1297:1311	arg1	sensor					1313:1318	The proposed electrochemical sensor	1284:1318	The proposed electrochemical sensor	1284:1318	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	2	1	theme	carbon	596:601	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	1	theme	carbon	596:601	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	6	2	theme	sensitivity	1343:1353	arg1	metrics					1382:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	4	3	theme	linear	950:955	arg1	LSV					976:978	LSV	976:978	LSV	976:978	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	3	theme	linear	950:955	arg1	voltammetry					963:973	linear sweep voltammetry	950:973	linear sweep voltammetry (LSV)	950:979	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	5	4	theme	detection	1222:1230	arg1	value					1238:1242	detection (LOD) value	1222:1242	detection (LOD) value of 0.8 nM determined by the DPV method	1222:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	2	5	theme	electrochemical	499:513	arg1	performance					515:525	the electrochemical performance	495:525	the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples	495:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	1	6	theme	human	365:369	arg1	health					371:376	human health	365:376	human health	365:376	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	6	7	theme	proposed	1288:1295	arg1	sensor					1313:1318	The proposed electrochemical sensor	1284:1318	The proposed electrochemical sensor	1284:1318	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	2	8	theme	water	693:697	arg1	samples					699:705	water samples	693:705	water samples	693:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	5	9	theme	low	1195:1197	arg1	amount					1199:1204	a low amount	1193:1204	a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1193:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	9	theme	low	1195:1197	arg1	limit					1213:1217	the limit	1209:1217	the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1209:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	10	theme	DPV	1272:1274	arg1	method					1276:1281	the DPV method	1268:1281	the DPV method	1268:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	0	11	theme	electrochemical	101:115	arg1	sensor					117:122	an electrochemical sensor	98:122	an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant	98:187	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	3	12	theme	microscopy	734:743	arg1	technique					751:759	The transmission electron microscopy (TEM) technique	708:759	The transmission electron microscopy (TEM) technique	708:759	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	5	13	theme	optimized	1038:1046	arg1	conditions					1059:1068	optimized analytical conditions	1038:1068	optimized analytical conditions	1038:1068	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	4	14	theme	impedance	1002:1010	arg1	EIS					1026:1028	EIS	1026:1028	EIS	1026:1028	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	14	theme	impedance	1002:1010	arg1	spectroscopy					1012:1023	electrochemical impedance spectroscopy	986:1023	electrochemical impedance spectroscopy (EIS)	986:1029	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	2	15	theme	nanofibril	557:566	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	15	theme	nanofibril	557:566	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	3	16	theme	electron	725:732	arg1	TEM					746:748	TEM	746:748	TEM	746:748	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	3	16	theme	electron	725:732	arg1	microscopy					734:743	transmission electron microscopy	712:743	The transmission electron microscopy (TEM) technique	708:759	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	6	17	theme	real	1393:1396	arg1	analysis					1405:1412	real sample analysis	1393:1412	real sample analysis of p-nitrophenol	1393:1429	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	2	18	theme	p-nitrophenol	676:688	arg1	detection					663:671	the sensitive and reliable detection	636:671	the sensitive and reliable detection of p-nitrophenol in water samples	636:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	6	19	theme	selectivity	1356:1366	arg1	metrics					1382:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	2	20	theme	oxide/cellulose	541:555	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	20	theme	oxide/cellulose	541:555	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	0	21	theme	sensor	117:122	arg1	fabrication					83:93	the fabrication	79:93	the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant	79:187	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	1	22	theme	regulatory	388:397	arg1	compliance					399:408	regulatory compliance	388:408	regulatory compliance	388:408	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	2	23	theme	reliable	654:661	arg1	detection					663:671	the sensitive and reliable detection	636:671	the sensitive and reliable detection of p-nitrophenol in water samples	636:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	24	from	detection	663:671	arg1	samples					699:705	water samples	693:705	water samples	693:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	0	25	theme	oxide/cellulose	9:23	arg1	composite					36:44	Graphene oxide/cellulose nanofibril composite	0:44	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.	0:188	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	4	26	theme	sweep	957:961	arg1	LSV					976:978	LSV	976:978	LSV	976:978	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	26	theme	sweep	957:961	arg1	voltammetry					963:973	linear sweep voltammetry	950:973	linear sweep voltammetry (LSV)	950:979	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	27	theme	pulse	925:929	arg1	DPV					944:946	DPV	944:946	DPV	944:946	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	27	theme	pulse	925:929	arg1	voltammetry					931:941	differential pulse voltammetry	912:941	differential pulse voltammetry (DPV)	912:947	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	28	theme	electrochemical	986:1000	arg1	EIS					1026:1028	EIS	1026:1028	EIS	1026:1028	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	28	theme	electrochemical	986:1000	arg1	spectroscopy					1012:1023	electrochemical impedance spectroscopy	986:1023	electrochemical impedance spectroscopy (EIS)	986:1029	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	6	29	theme	excellent	1333:1341	arg1	metrics					1382:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	0	30	theme	Graphene	0:7	arg1	composite					36:44	Graphene oxide/cellulose nanofibril composite	0:44	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.	0:188	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	2	31	theme	sensitive	640:648	arg1	detection					663:671	the sensitive and reliable detection	636:671	the sensitive and reliable detection of p-nitrophenol in water samples	636:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	5	32	theme	analytical	1048:1057	arg1	conditions					1059:1068	optimized analytical conditions	1038:1068	optimized analytical conditions	1038:1068	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	2	33	theme	modified	587:594	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	33	theme	modified	587:594	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	6	34	theme	accuracy	1373:1380	arg1	metrics					1382:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	excellent sensitivity, selectivity, and accuracy metrics	1333:1388	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	6	35	theme	sample	1398:1403	arg1	analysis					1405:1412	real sample analysis	1393:1412	real sample analysis of p-nitrophenol	1393:1429	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	4	36	theme	electrochemical	867:881	arg1	sensor					883:888	the fabricated electrochemical sensor	852:888	the fabricated electrochemical sensor	852:888	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	2	37	theme	main	448:451	arg1	objective					453:461	The main objective	444:461	The main objective of this work	444:474	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	0	38	theme	nanofibril	25:34	arg1	composite					36:44	Graphene oxide/cellulose nanofibril composite	0:44	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.	0:188	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	5	39	theme	limit	1213:1217	arg1	amount					1199:1204	a low amount	1193:1204	a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1193:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	39	theme	limit	1213:1217	arg1	limit					1213:1217	the limit	1209:1217	the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1209:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	3	40	theme	nanocomposites	804:817	arg1	structure					791:799	the structure	787:799	the structure of nanocomposites	787:817	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	2	41	theme	GO/CNF	579:584	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	41	theme	GO/CNF	579:584	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	5	42	theme	wide	1112:1115	arg1	relationship					1124:1135	a wide linear relationship	1110:1135	a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1110:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	1	43	dep	detection	194:202	arg1	The					190:192	The	190:192	The	190:192	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	1	44	theme	p-Nitrophenol	226:238	arg1	detection					194:202	detection	194:202	detection	194:202	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	1	44	theme	p-Nitrophenol	226:238	arg1	quantification					208:221	quantification	208:221	quantification	208:221	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	0	45	theme	p-nitrophenol	146:158	arg1	quantification					128:141	quantification	128:141	quantification of p-nitrophenol, a hazardous water pollutant	128:187	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	5	46	theme	linear	1117:1122	arg1	relationship					1124:1135	a wide linear relationship	1110:1135	a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1110:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	4	47	theme	fabricated	856:865	arg1	sensor					883:888	the fabricated electrochemical sensor	852:888	the fabricated electrochemical sensor	852:888	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	2	48	theme	graphene	532:539	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	48	theme	graphene	532:539	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	49	theme	composite	568:576	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	49	theme	composite	568:576	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	0	50	theme	hazardous	163:171	arg1	p-nitrophenol					146:158	p-nitrophenol	146:158	p-nitrophenol	146:158	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	0	50	theme	hazardous	163:171	arg1	pollutant					179:187	a hazardous water pollutant	161:187	a hazardous water pollutant	161:187	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	1	51	theme	remediation	423:433	arg1	efforts					435:441	remediation efforts	423:441	remediation efforts	423:441	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	5	52	theme	peak	1075:1078	arg1	current					1080:1086	the peak current	1071:1086	the peak current of the analyte	1071:1101	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	4	53	theme	differential	912:923	arg1	DPV					944:946	DPV	944:946	DPV	944:946	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	4	53	theme	differential	912:923	arg1	voltammetry					931:941	differential pulse voltammetry	912:941	differential pulse voltammetry (DPV)	912:947	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	0	54	theme	high-performance	49:64	arg1	catalyst					66:73	A high-performance catalyst	47:73	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.	0:188	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	1	55	theme	environmental	329:341	arg1	pollution					343:351	environmental pollution	329:351	environmental pollution	329:351	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	2	56	theme	electrode	609:617	arg1	performance					515:525	the electrochemical performance	495:525	the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples	495:705	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	4	57	theme	sensor	883:888	arg1	behavior					840:847	The electrochemical behavior	820:847	The electrochemical behavior of the fabricated electrochemical sensor	820:888	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	1	58	from	quantification	208:221	arg1	samples					264:270	environmental samples	250:270	environmental samples	250:270	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	5	59	from	concentration	1146:1158	arg1	range					1165:1169	a range	1163:1169	a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1163:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	1	60	theme	pollution	343:351	arg1	extent					308:313	extent	308:313	extent	308:313	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	1	60	theme	pollution	343:351	arg1	impact					319:324	impact	319:324	impact	319:324	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	2	61	theme	paste	603:607	arg1	GO/CNF/CPE					620:629	GO/CNF/CPE	620:629	GO/CNF/CPE	620:629	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	2	61	theme	paste	603:607	arg1	electrode					609:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode	530:617	a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE)	530:630	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	3	62	theme	transmission	712:723	arg1	TEM					746:748	TEM	746:748	TEM	746:748	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	3	62	theme	transmission	712:723	arg1	microscopy					734:743	transmission electron microscopy	712:743	The transmission electron microscopy (TEM) technique	708:759	The transmission electron microscopy (TEM) technique was employed to enlighten the structure of nanocomposites.					
37127202	0	63	dep	composite	36:44	arg1	catalyst					66:73	A high-performance catalyst	47:73	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.	0:188	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	5	64	theme	value	1238:1242	arg1	limit					1213:1217	the limit	1209:1217	the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1209:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	0	65	theme	water	173:177	arg1	p-nitrophenol					146:158	p-nitrophenol	146:158	p-nitrophenol	146:158	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	0	65	theme	water	173:177	arg1	pollutant					179:187	a hazardous water pollutant	161:187	a hazardous water pollutant	161:187	Graphene oxide/cellulose nanofibril composite: A high-performance catalyst for the fabrication of an electrochemical sensor for quantification of p-nitrophenol, a hazardous water pollutant.					
37127202	5	66	theme	analyte	1095:1101	arg1	current					1080:1086	the peak current	1071:1086	the peak current of the analyte	1071:1101	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	4	67	theme	electrochemical	824:838	arg1	behavior					840:847	The electrochemical behavior	820:847	The electrochemical behavior of the fabricated electrochemical sensor	820:888	The electrochemical behavior of the fabricated electrochemical sensor was characterized via differential pulse voltammetry (DPV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS).					
37127202	1	68	from	detection	194:202	arg1	samples					264:270	environmental samples	250:270	environmental samples	250:270	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	5	69	with	relationship	1124:1135	arg1	concentration					1146:1158	its concentration	1142:1158	its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1142:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	6	70	theme	p-nitrophenol	1417:1429	arg1	analysis					1405:1412	real sample analysis	1393:1412	real sample analysis of p-nitrophenol	1393:1429	The proposed electrochemical sensor demonstrated excellent sensitivity, selectivity, and accuracy metrics in real sample analysis of p-nitrophenol.					
37127202	5	71	with	range	1165:1169	arg1	amount					1199:1204	a low amount	1193:1204	a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1193:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	71	with	range	1165:1169	arg1	limit					1213:1217	the limit	1209:1217	the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1209:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	72	theme	3.0 nM-210 μM	1174:1186	arg1	range					1165:1169	a range	1163:1169	a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method	1163:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	73	theme	0.8 nM	1247:1252	arg1	value					1238:1242	detection (LOD) value	1222:1242	detection (LOD) value of 0.8 nM determined by the DPV method	1222:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	5	74	theme	LOD	1233:1235	arg1	value					1238:1242	detection (LOD) value	1222:1242	detection (LOD) value of 0.8 nM determined by the DPV method	1222:1281	Under optimized analytical conditions, the peak current of the analyte showed a wide linear relationship with its concentration in a range of 3.0 nM-210 μM with a low amount of the limit of detection (LOD) value of 0.8 nM determined by the DPV method.					
37127202	1	75	dep	extent	308:313	arg1	the					304:306	the	304:306	the	304:306	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
37127202	2	76	theme	work	471:474	arg1	objective					453:461	The main objective	444:461	The main objective of this work	444:474	The main objective of this work was to investigate the electrochemical performance of a graphene oxide/cellulose nanofibril composite (GO/CNF) modified carbon paste electrode (GO/CNF/CPE) for the sensitive and reliable detection of p-nitrophenol in water samples.					
37127202	1	77	theme	environmental	250:262	arg1	samples					264:270	environmental samples	250:270	environmental samples	250:270	The detection and quantification of p-Nitrophenol (p-NP) in environmental samples are important for understanding the extent and impact of environmental pollution, protecting human health, ensuring regulatory compliance, and guiding remediation efforts.					
35952870	9	0	theme	VFA	1405:1407	arg1	yield					1409:1413	the VFA yield	1401:1413	the VFA yield of WAS/FW co-fermentation	1401:1439	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	9	1	theme	certain	1544:1550	arg1	extent					1552:1557	a certain extent	1542:1557	a certain extent	1542:1557	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	6	2	theme	carbohydrate-rich	1110:1126	arg1	component					1128:1136	a carbohydrate-rich component	1108:1136	a carbohydrate-rich component	1108:1136	A positive interaction on VFA yield was observed when mixing a protein-rich and a carbohydrate-rich component.					
35952870	1	3	theme	co-fermentation	137:151	arg1	performance					153:163	co-fermentation performance	137:163	co-fermentation performance	137:163	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	6	4	from	interaction	1039:1049	arg1	yield					1058:1062	VFA yield	1054:1062	VFA yield	1054:1062	A positive interaction on VFA yield was observed when mixing a protein-rich and a carbohydrate-rich component.					
35952870	4	5	theme	no	802:803	arg1	control					808:814	no pH control	802:814	no pH control	802:814	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	0	6	from	Impact	0:5	arg1	co-fermentation					47:61	acidogenic co-fermentation	36:61	acidogenic co-fermentation with waste	36:72	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	9	7	theme	FW	1464:1465	arg1	composition					1467:1477	FW composition	1464:1477	FW composition	1464:1477	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	6	8	theme	VFA	1054:1056	arg1	yield					1058:1062	VFA yield	1054:1062	VFA yield	1054:1062	A positive interaction on VFA yield was observed when mixing a protein-rich and a carbohydrate-rich component.					
35952870	4	9	theme	mesophilic	664:673	arg1	assays					681:686	mesophilic batch assays	664:686	mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control	664:814	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	6	10	dep	protein-rich	1091:1102	arg1	a					1089:1089	a	1089:1089	a	1089:1089	A positive interaction on VFA yield was observed when mixing a protein-rich and a carbohydrate-rich component.					
35952870	8	11	theme	FW	1337:1338	arg1	composition					1340:1350	FW composition	1337:1350	FW composition	1337:1350	On the other hand, the VFA profile was clearly driven by the components in the mixture, including both WAS and FW composition.					
35952870	6	12	theme	positive	1030:1037	arg1	interaction					1039:1049	A positive interaction	1028:1049	A positive interaction on VFA yield	1028:1062	A positive interaction on VFA yield was observed when mixing a protein-rich and a carbohydrate-rich component.					
35952870	9	13	theme	co-fermentation	1425:1439	arg1	yield					1409:1413	the VFA yield	1401:1413	the VFA yield of WAS/FW co-fermentation	1401:1439	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	1	14	theme	fermentation	243:254	arg1	yield					256:260	the fermentation yield	239:260	the fermentation yield	239:260	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	1	14	theme	fermentation	243:254	arg1	relevant					284:291	relevant	284:291	relevant	284:291	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	4	15	theme	same	746:749	arg1	sludge					710:715	waste activated sludge	694:715	waste activated sludge (WAS)	694:721	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	15	theme	same	746:749	arg1	ratio					759:763	the same mixture ratio	742:763	the same mixture ratio (70 % WAS +30 % FW on VS basis)	742:795	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	16	theme	activated	700:708	arg1	sludge					710:715	waste activated sludge	694:715	waste activated sludge (WAS)	694:721	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	16	theme	activated	700:708	arg1	ratio					759:763	the same mixture ratio	742:763	the same mixture ratio (70 % WAS +30 % FW on VS basis)	742:795	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	17	theme	pH	805:806	arg1	control					808:814	no pH control	802:814	no pH control	802:814	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	5	18	theme	highest	945:951	arg1	yields					957:962	the highest VFA yields	941:962	the highest VFA yields; 502 and 442 mgCOD/gVS	941:985	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	8	19	from	components	1287:1296	arg1	mixture					1305:1311	the mixture	1301:1311	the mixture	1301:1311	On the other hand, the VFA profile was clearly driven by the components in the mixture, including both WAS and FW composition.					
35952870	4	20	theme	waste	694:698	arg1	sludge					710:715	waste activated sludge	694:715	waste activated sludge (WAS)	694:721	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	20	theme	waste	694:698	arg1	ratio					759:763	the same mixture ratio	742:763	the same mixture ratio (70 % WAS +30 % FW on VS basis)	742:795	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	7	21	from	proportion	1198:1207	arg1	mixtures					1216:1223	the mixtures	1212:1223	the mixtures	1212:1223	This interaction was not proportional to the co-substrates proportion in the mixtures.					
35952870	2	22	theme	components	358:367	arg1	impact					334:339	the impact	330:339	the impact of individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose)	330:433	First, the impact of individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose) was assessed.					
35952870	4	23	dep	ratio	759:763	arg1	%					769:769	70 %	766:769	70 % WAS +30 % FW on VS basis	766:794	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	5	24	theme	VFA	953:955	arg1	yields					957:962	the highest VFA yields	941:962	the highest VFA yields; 502 and 442 mgCOD/gVS	941:985	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	9	25	theme	FW	1484:1485	arg1	composition					1487:1497	FW composition	1484:1497	FW composition	1484:1497	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	2	26	theme	FW	355:356	arg1	components					358:367	individual FW components	344:367	individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose)	344:433	First, the impact of individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose) was assessed.					
35952870	4	27	theme	mixture	751:757	arg1	sludge					710:715	waste activated sludge	694:715	waste activated sludge (WAS)	694:721	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	4	27	theme	mixture	751:757	arg1	ratio					759:763	the same mixture ratio	742:763	the same mixture ratio (70 % WAS +30 % FW on VS basis)	742:795	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	3	28	theme	protein-rich	486:497	arg1	component					499:507	a protein-rich component	484:507	a protein-rich component	484:507	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	2	29	theme	individual	344:353	arg1	components					358:367	individual FW components	344:367	individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose)	344:433	First, the impact of individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose) was assessed.					
35952870	0	30	theme	waste	15:19	arg1	composition					21:31	food waste composition	10:31	food waste composition	10:31	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	9	31	theme	WAS/FW	1418:1423	arg1	co-fermentation					1425:1439	WAS/FW co-fermentation	1418:1439	WAS/FW co-fermentation	1418:1439	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	4	32	theme	batch	675:679	arg1	assays					681:686	mesophilic batch assays	664:686	mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control	664:814	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	8	33	theme	other	1233:1237	arg1	hand					1239:1242	the other hand	1229:1242	the other hand	1229:1242	On the other hand, the VFA profile was clearly driven by the components in the mixture, including both WAS and FW composition.					
35952870	0	34	theme	food	10:13	arg1	composition					21:31	food waste composition	10:31	food waste composition	10:31	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	5	35	dep	yields	957:962	arg1	mgCOD/gVS					977:985	502 and 442 mgCOD/gVS	965:985	the highest VFA yields; 502 and 442 mgCOD/gVS	941:985	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	9	36	used	used	1508:1511	arg2	composition					1487:1497	FW composition	1484:1497	FW composition	1484:1497	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	3	37	theme	mixing	477:482	arg1	component					499:507	a protein-rich component	484:507	a protein-rich component	484:507	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	4	38	theme	main	726:729	arg1	substrate					731:739	main substrate	726:739	main substrate	726:739	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	3	39	dep	studied	547:553	arg1	meat/vegetable					611:624	meat/vegetable	611:624	meat/vegetable	611:624	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	3	39	dep	studied	547:553	arg1	meat/rice					597:605	meat/rice	597:605	meat/rice	597:605	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	0	40	theme	composition	21:31	arg1	Impact					0:5	Impact	0:5	Impact of food waste composition on acidogenic co-fermentation with waste	0:72	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	5	41	theme	protein-rich	908:919	arg1	components					921:930	protein-rich components	908:930	protein-rich components	908:930	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	3	42	theme	carbohydrate-rich	515:531	arg1	component					533:541	a carbohydrate-rich component	513:541	a carbohydrate-rich component	513:541	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	1	43	theme	FW	203:204	arg1	composition					206:216	FW composition	203:216	FW composition	203:216	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	4	44	theme	%	779:779	arg1	FW					781:782	+30 % FW	775:782	+30 % FW	775:782	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	3	45	theme	component	499:507	arg1	effect					467:472	the effect	463:472	the effect of mixing a protein-rich component and a carbohydrate-rich component	463:541	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	1	46	theme	food	106:109	arg1	FW					118:119	FW	118:119	FW	118:119	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	1	46	theme	food	106:109	arg1	waste					111:115	food waste	106:115	food waste (FW) composition	106:132	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	0	47	theme	acidogenic	36:45	arg1	co-fermentation					47:61	acidogenic co-fermentation	36:61	acidogenic co-fermentation with waste	36:72	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	4	48	theme	+30	775:777	arg1	%					779:779	%	779:779	%	779:779	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	5	49	theme	VFA	880:882	arg1	yield					884:888	VFA yield	880:888	VFA yield	880:888	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	2	50	dep	fruit	376:380	arg1	i.e.					370:373	i.e.	370:373	i.e.	370:373	First, the impact of individual FW components (i.e., fruit, vegetables, pasta, rice, meat, fish, and cellulose) was assessed.					
35952870	1	51	theme	waste	111:115	arg1	composition					122:132	food waste (FW) composition	106:132	food waste (FW) composition	106:132	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	1	52	from	impact	96:101	arg1	performance					153:163	co-fermentation performance	137:163	co-fermentation performance	137:163	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	9	53	theme	VFA	1527:1529	arg1	profile					1531:1537	the VFA profile	1523:1537	the VFA profile	1523:1537	Overall, these results indicate that predicting the VFA yield of WAS/FW co-fermentation is not just related to FW composition, but FW composition could be used to adjust the VFA profile to a certain extent.					
35952870	4	54	from	FW	781:782	arg1	basis					790:794	VS basis	787:794	basis	790:794	All experiments were carried out in mesophilic batch assays using waste activated sludge (WAS) as main substrate, the same mixture ratio (70 % WAS +30 % FW on VS basis), and no pH control.					
35952870	8	55	theme	VFA	1249:1251	arg1	profile					1253:1259	the VFA profile	1245:1259	the VFA profile	1245:1259	On the other hand, the VFA profile was clearly driven by the components in the mixture, including both WAS and FW composition.					
35952870	5	56	theme	distinct	861:868	arg1	effect					870:875	a distinct effect	859:875	a distinct effect	859:875	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	5	57	theme	FW	842:843	arg1	component					845:853	each FW component	837:853	each FW component	837:853	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	0	58	with	co-fermentation	47:61	arg1	waste					68:72	waste	68:72	waste	68:72	Impact of food waste composition on acidogenic co-fermentation with waste activated sludge.					
35952870	3	59	theme	component	533:541	arg1	effect					467:472	the effect	463:472	the effect of mixing a protein-rich component and a carbohydrate-rich component	463:541	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	3	60	dep	fish/fruit	562:571	arg1	i.e.					556:559	i.e.	556:559	i.e.	556:559	Subsequently, the effect of mixing a protein-rich component and a carbohydrate-rich component was studied (i.e., fish/fruit and fish/cellulose, and meat/rice and meat/vegetable).					
35952870	1	61	theme	biorefinery	297:307	arg1	applications					309:320	biorefinery applications	297:320	biorefinery applications	297:320	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	7	62	theme	co-substrates	1184:1196	arg1	proportion					1198:1207	the co-substrates proportion	1180:1207	the co-substrates proportion in the mixtures	1180:1223	This interaction was not proportional to the co-substrates proportion in the mixtures.					
35952870	1	63	theme	composition	122:132	arg1	impact					96:101	The impact	92:101	The impact of food waste (FW) composition on co-fermentation performance	92:163	The impact of food waste (FW) composition on co-fermentation performance was studied to elucidate if adjusting FW composition can be used to drive the fermentation yield and profile, which is relevant for biorefinery applications.					
35952870	5	64	contain	had	855:857	arg1	component					845:853	each FW component	837:853	each FW component	837:853	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
35952870	5	64	contain	had	855:857	arg2	effect					870:875	a distinct effect	859:875	a distinct effect	859:875	Results showed that each FW component had a distinct effect on VFA yield and profile, with protein-rich components reaching the highest VFA yields; 502 and 442 mgCOD/gVS for WAS/Fish and WAS/Meat, respectively.					
36207633	4	0	theme	efficient	809:817	arg1	removal					825:831	a more efficient U(VI) removal	802:831	a more efficient U(VI) removal	802:831	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	5	1	theme	294.12 mg·g-1	915:927	arg1	capacity					903:910	a maximum adsorption capacity	882:910	a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40	882:944	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	1	2	theme	large	145:149	arg1	wastewater					181:190	uranium-containing wastewater	162:190	uranium-containing wastewater	162:190	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	2	theme	large	145:149	arg1	hazards					210:216	its potential hazards	196:216	its potential hazards	196:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	2	theme	large	145:149	arg1	amounts					151:157	large amounts	145:157	large amounts of uranium-containing wastewater and its potential hazards	145:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	3	theme	material	253:260	arg1	removal					262:268	efficient material removal	243:268	efficient material removal of uranium (VI)	243:284	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	6	4	from	mechanism	980:988	arg1	solutions					1052:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	1	5	theme	amounts	151:157	arg1	production					131:140	The production	127:140	The production of large amounts of uranium-containing wastewater and its potential hazards	127:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	6	6	theme	acidic	1006:1011	arg1	solutions					1052:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	3	7	theme	U	650:650	arg1	efficiency					667:676	their U(VI) adsorption efficiency	644:676	their U(VI) adsorption efficiency	644:676	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	4	8	theme	specific	775:782	arg1	area					792:795	larger specific surface area	768:795	larger specific surface area	768:795	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	5	9	theme	maximum	884:890	arg1	capacity					903:910	a maximum adsorption capacity	882:910	a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40	882:944	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	3	10	theme	precursors	523:532	arg1	precursors					523:532	precursors	523:532	precursors	523:532	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	10	theme	precursors	523:532	arg1	temperature					493:503	the reaction temperature	480:503	the reaction temperature	480:503	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	10	theme	precursors	523:532	arg1	amount					513:518	the amount	509:518	the amount of precursors	509:532	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	4	11	theme	U	819:819	arg1	removal					825:831	a more efficient U(VI) removal	802:831	a more efficient U(VI) removal	802:831	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	2	12	theme	facile	337:342	arg1	synthesis					372:380	a facile and eco-friendly biomimetic synthesis	335:380	a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP)	335:409	Inspired by the natural mineralization of bone, a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP) was carried out using chitosan (CS) as a template.					
36207633	1	13	theme	uranium	273:279	arg1	removal					262:268	efficient material removal	243:268	efficient material removal of uranium (VI)	243:284	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	13	theme	uranium	273:279	arg1	green					233:237	stimulated green	222:237	stimulated green	222:237	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	3	14	theme	reaction	484:491	arg1	temperature					493:503	the reaction temperature	480:503	the reaction temperature	480:503	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	2	15	theme	nano-hydroxyapatite	385:403	arg1	synthesis					372:380	a facile and eco-friendly biomimetic synthesis	335:380	a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP)	335:409	Inspired by the natural mineralization of bone, a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP) was carried out using chitosan (CS) as a template.					
36207633	4	16	theme	surface	784:790	arg1	area					792:795	larger specific surface area	768:795	larger specific surface area	768:795	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	4	17	theme	smaller	720:726	arg1	size					737:740	smaller particle size	720:740	smaller particle size	720:740	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	1	18	theme	uranium-containing	162:179	arg1	wastewater					181:190	uranium-containing wastewater	162:190	uranium-containing wastewater	162:190	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	0	19	theme	uranium	10:16	arg1	adsorbing					22:30	Efficient uranium(VI) adsorbing	0:30	Efficient uranium(VI) adsorbing	0:30	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	3	20	theme	adsorption	656:665	arg1	efficiency					667:676	their U(VI) adsorption efficiency	644:676	their U(VI) adsorption efficiency	644:676	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	7	21	dep	mechanisms	1138:1147	arg1	VI					1123:1124	VI	1123:1124	VI	1123:1124	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	2	22	theme	natural	303:309	arg1	mineralization					311:324	the natural mineralization	299:324	the natural mineralization of bone	299:332	Inspired by the natural mineralization of bone, a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP) was carried out using chitosan (CS) as a template.					
36207633	1	23	theme	wastewater	181:190	arg1	wastewater					181:190	uranium-containing wastewater	162:190	uranium-containing wastewater	162:190	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	23	theme	wastewater	181:190	arg1	hazards					210:216	its potential hazards	196:216	its potential hazards	196:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	23	theme	wastewater	181:190	arg1	amounts					151:157	large amounts	145:157	large amounts of uranium-containing wastewater and its potential hazards	145:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	0	24	theme	Efficient	0:8	arg1	adsorbing					22:30	Efficient uranium(VI) adsorbing	0:30	Efficient uranium(VI) adsorbing	0:30	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	6	25	theme	aqueous	1044:1050	arg1	solutions					1052:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	2	26	theme	biomimetic	361:370	arg1	synthesis					372:380	a facile and eco-friendly biomimetic synthesis	335:380	a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP)	335:409	Inspired by the natural mineralization of bone, a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP) was carried out using chitosan (CS) as a template.					
36207633	4	27	theme	larger	768:773	arg1	area					792:795	larger specific surface area	768:795	larger specific surface area	768:795	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	4	28	theme	synthesized	693:703	arg1	CS/HAP-40					705:713	the synthesized CS/HAP-40	689:713	the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area	689:795	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	5	29	contain	has	878:880	arg2	capacity					903:910	a maximum adsorption capacity	882:910	a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40	882:944	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	5	29	contain	has	878:880	arg1	It					875:876	It	875:876	It	875:876	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	0	30	theme	adsorption	105:114	arg1	mechanism					116:124	adsorption mechanism	105:124	adsorption mechanism	105:124	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	7	31	from	pH	1152:1153	arg1	complexation					1174:1185	surface complexation	1166:1185	surface complexation	1166:1185	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	31	from	pH	1152:1153	arg1	mechanisms					1138:1147	the U(VI) adsorption mechanisms	1117:1147	the U(VI) adsorption mechanisms at pH 8	1117:1155	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	1	32	theme	potential	200:208	arg1	hazards					210:216	its potential hazards	196:216	its potential hazards	196:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	8	33	located	observed	1258:1265	arg1	contrary					1212:1219	the contrary	1208:1219	the contrary	1208:1219	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	8	33	located	observed	1258:1265	arg1	pH					1270:1271	pH 3	1270:1273	pH 3	1270:1273	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	8	33	located	observed	1258:1265	arg2	mechanisms					1238:1247	three different mechanisms	1222:1247	three different mechanisms	1222:1247	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	4	34	with	CS/HAP-40	705:713	arg1	size					737:740	smaller particle size	720:740	smaller particle size	720:740	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	4	34	with	CS/HAP-40	705:713	arg1	crystallinity					749:761	lower crystallinity	743:761	lower crystallinity	743:761	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	4	34	with	CS/HAP-40	705:713	arg1	area					792:795	larger specific surface area	768:795	larger specific surface area	768:795	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	3	35	theme	CS/HAP	610:615	arg1	nanorods					617:624	the CS/HAP nanorods	606:624	the CS/HAP nanorods	606:624	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	6	36	theme	removal	972:978	arg1	mechanism					980:988	the U(VI) removal mechanism	962:988	the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	962:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	6	36	theme	removal	972:978	arg1	different					1078:1086	different	1078:1086	different	1078:1086	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	1	37	theme	hazards	210:216	arg1	wastewater					181:190	uranium-containing wastewater	162:190	uranium-containing wastewater	162:190	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	37	theme	hazards	210:216	arg1	hazards					210:216	its potential hazards	196:216	its potential hazards	196:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	37	theme	hazards	210:216	arg1	amounts					151:157	large amounts	145:157	large amounts of uranium-containing wastewater and its potential hazards	145:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	6	38	theme	CS/HAP-40	993:1001	arg1	mechanism					980:988	the U(VI) removal mechanism	962:988	the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	962:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	6	38	theme	CS/HAP-40	993:1001	arg1	different					1078:1086	different	1078:1086	different	1078:1086	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	8	39	theme	form	1305:1308	arg1	chernikovite					1310:1321	form chernikovite	1305:1321	form chernikovite	1305:1321	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	8	40	theme	different	1228:1236	arg1	mechanisms					1238:1247	three different mechanisms	1222:1247	three different mechanisms	1222:1247	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	6	41	theme	U	966:966	arg1	mechanism					980:988	the U(VI) removal mechanism	962:988	the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	962:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	6	41	theme	U	966:966	arg1	different					1078:1086	different	1078:1086	different	1078:1086	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	0	42	theme	nano-sized	44:53	arg1	composites					70:79	nano-sized hydroxyapatite composites	44:79	nano-sized hydroxyapatite composites	44:79	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	4	43	dep	removal	825:831	arg1	VI					821:822	VI	821:822	VI	821:822	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	0	44	dep	adsorbing	22:30	arg1	VI					18:19	VI	18:19	VI	18:19	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	6	45	theme	alkaline	1026:1033	arg1	solutions					1052:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	acidic (pH = 3) and alkaline (pH = 8) aqueous solutions	1006:1060	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	7	46	theme	adsorption	1127:1136	arg1	complexation					1174:1185	surface complexation	1166:1185	surface complexation	1166:1185	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	46	theme	adsorption	1127:1136	arg1	mechanisms					1138:1147	the U(VI) adsorption mechanisms	1117:1147	the U(VI) adsorption mechanisms at pH 8	1117:1155	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	8	47	theme	ion	1350:1352	arg1	exchange					1354:1361	ion exchange	1350:1361	ion exchange	1350:1361	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	3	48	dep	efficiency	667:676	arg1	VI					652:653	VI	652:653	VI	652:653	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	7	49	theme	surface	1166:1172	arg1	complexation					1174:1185	surface complexation	1166:1185	surface complexation	1166:1185	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	49	theme	surface	1166:1172	arg1	mechanisms					1138:1147	the U(VI) adsorption mechanisms	1117:1147	the U(VI) adsorption mechanisms at pH 8	1117:1155	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	1	50	contain	has	218:220	arg2	removal					262:268	efficient material removal	243:268	efficient material removal of uranium (VI)	243:284	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	50	contain	has	218:220	arg2	green					233:237	stimulated green	222:237	stimulated green	222:237	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	1	50	contain	has	218:220	arg1	production					131:140	The production	127:140	The production of large amounts of uranium-containing wastewater and its potential hazards	127:216	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	3	51	theme	particle	548:555	arg1	size					557:560	particle size	548:560	particle size	548:560	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	6	52	dep	mechanism	980:988	arg1	VI					968:969	VI	968:969	VI	968:969	Interestingly, the U(VI) removal mechanism of CS/HAP-40 in acidic (pH = 3) and alkaline (pH = 8) aqueous solutions was found to be different.					
36207633	2	53	theme	bone	329:332	arg1	mineralization					311:324	the natural mineralization	299:324	the natural mineralization of bone	299:332	Inspired by the natural mineralization of bone, a facile and eco-friendly biomimetic synthesis of nano-hydroxyapatite (HAP) was carried out using chitosan (CS) as a template.					
36207633	5	54	theme	CS/HAP-40	936:944	arg1	294.12 mg·g-1					915:927	294.12 mg·g-1	915:927	294.12 mg·g-1 of the CS/HAP-40	915:944	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	1	55	dep	uranium	273:279	arg1	VI					282:283	VI	282:283	VI	282:283	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	3	56	theme	specific	581:588	arg1	area					598:601	specific surface area	581:601	specific surface area	581:601	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	1	57	theme	stimulated	222:231	arg1	green					233:237	stimulated green	222:237	stimulated green	222:237	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
36207633	4	58	theme	particle	728:735	arg1	size					737:740	smaller particle size	720:740	smaller particle size	720:740	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	3	59	theme	nanorods	617:624	arg1	size					557:560	particle size	548:560	particle size	548:560	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	59	theme	nanorods	617:624	arg1	area					598:601	specific surface area	581:601	specific surface area	581:601	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	59	theme	nanorods	617:624	arg1	efficiency					667:676	their U(VI) adsorption efficiency	644:676	their U(VI) adsorption efficiency	644:676	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	59	theme	nanorods	617:624	arg1	crystallinity					563:575	crystallinity	563:575	crystallinity	563:575	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	3	60	theme	surface	590:596	arg1	area					598:601	specific surface area	581:601	specific surface area	581:601	It was found that the reaction temperature and the amount of precursors influence the particle size, crystallinity and specific surface area of the CS/HAP nanorods, and consequently their U(VI) adsorption efficiency.					
36207633	8	61	dep	observed	1258:1265	arg1	dissolution-precipitation					1276:1300	dissolution-precipitation	1276:1300	dissolution-precipitation to form chernikovite, surface complexation, and ion exchange	1276:1361	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	7	62	theme	main	1103:1106	arg1	results					1108:1114	the main results	1099:1114	the main results	1099:1114	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	8	63	theme	surface	1324:1330	arg1	complexation					1332:1343	surface complexation	1324:1343	surface complexation	1324:1343	On the contrary, three different mechanisms could be observed at pH 3: dissolution-precipitation to form chernikovite, surface complexation, and ion exchange.					
36207633	7	64	theme	ion	1191:1193	arg1	exchange					1195:1202	ion exchange	1191:1202	ion exchange	1191:1202	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	65	theme	U	1121:1121	arg1	complexation					1174:1185	surface complexation	1166:1185	surface complexation	1166:1185	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	65	theme	U	1121:1121	arg1	mechanisms					1138:1147	the U(VI) adsorption mechanisms	1117:1147	the U(VI) adsorption mechanisms at pH 8	1117:1155	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	66	theme	results	1108:1114	arg1	one					1092:1094	one	1092:1094	one	1092:1094	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	7	66	theme	results	1108:1114	arg1	results					1108:1114	the main results	1099:1114	the main results	1099:1114	As one of the main results, the U(VI) adsorption mechanisms at pH 8 could be surface complexation and ion exchange.					
36207633	0	67	theme	hydroxyapatite	55:68	arg1	composites					70:79	nano-sized hydroxyapatite composites	44:79	nano-sized hydroxyapatite composites	44:79	Efficient uranium(VI) adsorbing bioinspired nano-sized hydroxyapatite composites: synthesis, tuning, and adsorption mechanism.					
36207633	5	68	theme	adsorption	892:901	arg1	capacity					903:910	a maximum adsorption capacity	882:910	a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40	882:944	It has a maximum adsorption capacity of 294.12 mg·g-1 of the CS/HAP-40.					
36207633	4	69	theme	lower	743:747	arg1	crystallinity					749:761	lower crystallinity	743:761	lower crystallinity	743:761	Moreover, the synthesized CS/HAP-40 with smaller particle size, lower crystallinity, and larger specific surface area show a more efficient U(VI) removal compared with CS/HAP-55 and CS/HAP-55-AT.					
36207633	1	70	theme	efficient	243:251	arg1	removal					262:268	efficient material removal	243:268	efficient material removal of uranium (VI)	243:284	The production of large amounts of uranium-containing wastewater and its potential hazards has stimulated green and efficient material removal of uranium (VI).					
35868797	4	0	theme	reactions	688:696	arg1	combination					656:666	The combination	652:666	The combination of the two chemical reactions	652:696	The combination of the two chemical reactions significantly improves the thermoelectric performance of the thermocell.					
35868797	7	1	theme	new	985:987	arg1	potential					989:997	new potential	985:997	new potential	985:997	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	3	2	theme	thermoelectric	496:509	arg1	ions					511:514	thermoelectric ions	496:514	thermoelectric ions	496:514	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	0	3	theme	heat	92:95	arg1	harvesting					97:106	efficient heat harvesting	82:106	efficient heat harvesting	82:106	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	3	4	theme	redox	534:538	arg1	reaction					540:547	the redox reaction	530:547	the redox reaction inside the electrolyte	530:570	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	3	5	theme	carbon	433:438	arg1	paper					446:450	carbon fiber paper	433:450	carbon fiber paper	433:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	7	6	theme	thermoelectric	1024:1037	arg1	conversion					1046:1055	ambient thermoelectric energy conversion	1016:1055	ambient thermoelectric energy conversion	1016:1055	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	3	7	theme	active	479:484	arg1	sites					486:490	active sites	479:490	active sites for thermoelectric ions	479:514	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	3	8	theme	sites	486:490	arg1	number					469:474	a large number	461:474	a large number	461:474	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	5	9	theme	temperature	825:835	arg1	difference					837:846	a temperature difference	823:846	a temperature difference of 50 K	823:854	The thermopower of the BC-TEC reaches 5.9 mV·K-1 at a temperature difference of 50 K.					
35868797	3	10	theme	fiber	440:444	arg1	paper					446:450	carbon fiber paper	433:450	carbon fiber paper	433:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	3	11	theme	surface	417:423	arg1	area					425:428	The large specific surface area	398:428	The large specific surface area of carbon fiber paper	398:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	3	12	theme	paper	446:450	arg1	area					425:428	The large specific surface area	398:428	The large specific surface area of carbon fiber paper	398:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	0	13	theme	cellulose-based	10:24	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	5	14	theme	BC-TEC	794:799	arg1	thermopower					775:785	The thermopower	771:785	The thermopower of the BC-TEC	771:799	The thermopower of the BC-TEC reaches 5.9 mV·K-1 at a temperature difference of 50 K.					
35868797	4	15	theme	thermocell	759:768	arg1	performance					740:750	the thermoelectric performance	721:750	the thermoelectric performance of the thermocell	721:768	The combination of the two chemical reactions significantly improves the thermoelectric performance of the thermocell.					
35868797	6	16	theme	open-circuit	909:920	arg1	voltage					922:928	an open-circuit voltage	906:928	an open-circuit voltage of about 2 V and a peak power of 535 μW	906:968	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	0	17	theme	Bacterial	0:8	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	1	18	from	utilization	134:144	arg1	nature					177:182	nature	177:182	nature	177:182	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	2	19	theme	BC	311:312	arg1	electrolyte					314:324	BC electrolyte	311:324	BC electrolyte combined with carbon fiber paper and copper composite electrode sheets	311:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	1	20	theme	sustainable	202:212	arg1	development					221:231	sustainable energy development	202:231	sustainable energy development	202:231	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	0	21	theme	chemical	31:38	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	7	22	theme	power	1085:1089	arg1	principle					1102:1110	the power generation principle	1081:1110	the power generation principle	1081:1110	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	6	23	from	6-units	879:885	arg1	series					890:895	series	890:895	series	890:895	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	3	24	theme	chemical	591:598	arg1	reaction					600:607	the chemical reaction	587:607	the chemical reaction between the electrolyte and the electrode	587:649	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	1	25	theme	energy	214:219	arg1	development					221:231	sustainable energy development	202:231	sustainable energy development	202:231	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	1	26	theme	Reasonable	109:118	arg1	utilization					134:144	Reasonable and efficient utilization	109:144	Reasonable and efficient utilization of low-grade thermal energy in nature	109:182	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	1	26	theme	Reasonable	109:118	arg1	choice					191:196	the choice	187:196	the choice for sustainable energy development	187:231	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	7	27	theme	generation	1091:1100	arg1	principle					1102:1110	the power generation principle	1081:1110	the power generation principle	1081:1110	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	1	28	theme	efficient	124:132	arg1	utilization					134:144	Reasonable and efficient utilization	109:144	Reasonable and efficient utilization of low-grade thermal energy in nature	109:182	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	1	28	theme	efficient	124:132	arg1	choice					191:196	the choice	187:196	the choice for sustainable energy development	187:231	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	6	29	theme	2 V	939:941	arg1	voltage					922:928	an open-circuit voltage	906:928	an open-circuit voltage of about 2 V and a peak power of 535 μW	906:968	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	2	30	theme	composite	370:378	arg1	sheets					390:395	copper composite electrode sheets	363:395	copper composite electrode sheets	363:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	0	31	theme	coupled	49:55	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	6	32	theme	535 μW	963:968	arg1	power					954:958	a peak power	947:958	a peak power of 535 μW	947:968	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	6	32	theme	535 μW	963:968	arg1	2 V					939:941	2 V	939:941	2 V	939:941	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	2	33	theme	cellulose	261:269	arg1	TEC					297:299	TEC	297:299	TEC	297:299	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	2	33	theme	cellulose	261:269	arg1	thermocell					285:294	a bacterial cellulose (BC) hydrogel thermocell	249:294	a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets	249:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	2	34	theme	electrode	380:388	arg1	sheets					390:395	copper composite electrode sheets	363:395	copper composite electrode sheets	363:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	0	35	theme	reaction	40:47	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	3	36	theme	the	637:639	arg1	electrode					641:649	the electrolyte and the electrode	617:649	electrode	641:649	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	2	37	theme	bacterial	251:259	arg1	TEC					297:299	TEC	297:299	TEC	297:299	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	2	37	theme	bacterial	251:259	arg1	thermocell					285:294	a bacterial cellulose (BC) hydrogel thermocell	249:294	a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets	249:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	7	38	theme	ambient	1016:1022	arg1	conversion					1046:1055	ambient thermoelectric energy conversion	1016:1055	ambient thermoelectric energy conversion	1016:1055	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	3	39	theme	large	402:406	arg1	area					425:428	The large specific surface area	398:428	The large specific surface area of carbon fiber paper	398:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	6	40	theme	power	954:958	arg1	voltage					922:928	an open-circuit voltage	906:928	an open-circuit voltage of about 2 V and a peak power of 535 μW	906:968	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	7	41	theme	energy	1039:1044	arg1	conversion					1046:1055	ambient thermoelectric energy conversion	1016:1055	ambient thermoelectric energy conversion	1016:1055	The TEC shows new potential and prospects in ambient thermoelectric energy conversion by rationally designing the power generation principle.					
35868797	2	42	theme	fiber	347:351	arg1	paper					353:357	carbon fiber paper	340:357	carbon fiber paper	340:357	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	3	43	theme	specific	408:415	arg1	area					425:428	The large specific surface area	398:428	The large specific surface area of carbon fiber paper	398:450	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	6	44	theme	peak	949:952	arg1	power					954:958	a peak power	947:958	a peak power of 535 μW	947:968	The TEC consisting of 6-units in series produces an open-circuit voltage of about 2 V and a peak power of 535 μW.					
35868797	2	45	theme	carbon	340:345	arg1	paper					353:357	carbon fiber paper	340:357	carbon fiber paper	340:357	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	4	46	theme	thermoelectric	725:738	arg1	performance					740:750	the thermoelectric performance	721:750	the thermoelectric performance of the thermocell	721:768	The combination of the two chemical reactions significantly improves the thermoelectric performance of the thermocell.					
35868797	3	47	theme	electrolyte	621:631	arg1	electrode					641:649	the electrolyte and the electrode	617:649	electrode	641:649	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	2	48	theme	hydrogel	276:283	arg1	TEC					297:299	TEC	297:299	TEC	297:299	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	2	48	theme	hydrogel	276:283	arg1	thermocell					285:294	a bacterial cellulose (BC) hydrogel thermocell	249:294	a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets	249:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	4	49	theme	chemical	679:686	arg1	reactions					688:696	the two chemical reactions	671:696	the two chemical reactions	671:696	The combination of the two chemical reactions significantly improves the thermoelectric performance of the thermocell.					
35868797	1	50	theme	low-grade	149:157	arg1	energy					167:172	low-grade thermal energy	149:172	low-grade thermal energy	149:172	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	5	51	theme	50 K	851:854	arg1	difference					837:846	a temperature difference	823:846	a temperature difference of 50 K	823:854	The thermopower of the BC-TEC reaches 5.9 mV·K-1 at a temperature difference of 50 K.					
35868797	1	52	theme	thermal	159:165	arg1	energy					167:172	low-grade thermal energy	149:172	low-grade thermal energy	149:172	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	0	53	theme	efficient	82:90	arg1	harvesting					97:106	efficient heat harvesting	82:106	efficient heat harvesting	82:106	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	2	54	theme	BC	272:273	arg1	TEC					297:299	TEC	297:299	TEC	297:299	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	2	54	theme	BC	272:273	arg1	thermocell					285:294	a bacterial cellulose (BC) hydrogel thermocell	249:294	a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets	249:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
35868797	3	55	theme	large	463:467	arg1	number					469:474	a large number	461:474	a large number	461:474	The large specific surface area of carbon fiber paper provides a large number of active sites for thermoelectric ions, which drives the redox reaction inside the electrolyte and stimulates the chemical reaction between the electrolyte and the electrode.					
35868797	1	56	theme	energy	167:172	arg1	utilization					134:144	Reasonable and efficient utilization	109:144	Reasonable and efficient utilization of low-grade thermal energy in nature	109:182	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	1	56	theme	energy	167:172	arg1	choice					191:196	the choice	187:196	the choice for sustainable energy development	187:231	Reasonable and efficient utilization of low-grade thermal energy in nature is the choice for sustainable energy development.					
35868797	0	57	theme	dual	26:29	arg1	hydrogel					57:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel	0:64	Bacterial cellulose-based dual chemical reaction coupled hydrogel thermocells for efficient heat harvesting.					
35868797	2	58	theme	copper	363:368	arg1	sheets					390:395	copper composite electrode sheets	363:395	copper composite electrode sheets	363:395	We demonstrate a bacterial cellulose (BC) hydrogel thermocell (TEC) based on BC electrolyte combined with carbon fiber paper and copper composite electrode sheets.					
36521702	7	0	theme	maximum	1049:1055	arg1	%					1136:1136	20.3 %	1131:1136	20.3 %	1131:1136	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	0	theme	maximum	1049:1055	arg1	cytotoxicity					1057:1068	the maximum cytotoxicity	1045:1068	the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7)	1045:1125	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	3	1	theme	ultrasonic	469:478	arg1	power					480:484	ultrasonic power	469:484	ultrasonic power	469:484	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	7	2	theme	poly	1011:1014	arg1	2.5					1037:1039	2.5	1037:1039	2.5	1037:1039	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	2	theme	poly	1011:1014	arg1	index					1027:1031	the minimum poly dispersity index	999:1031	the minimum poly dispersity index	999:1031	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	3	3	from	effect	400:405	arg1	ratio					514:518	ratio	514:518	ratio of monomers (M/G)	514:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	3	from	effect	400:405	arg1	yield					504:508	the extraction yield	489:508	the extraction yield	489:508	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	3	from	effect	400:405	arg1	M/G					533:535	M/G	533:535	M/G	533:535	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	2	4	theme	native	354:359	arg1	algae					348:352	brown algae	342:352	brown algae native to the coasts of the Persian Gulf	342:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	7	5	from	extract	1084:1090	arg1	MCF-7					1120:1124	MCF-7	1120:1124	MCF-7	1120:1124	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	5	from	extract	1084:1090	arg1	line					1114:1117	breast cancer cell line	1095:1117	breast cancer cell line (MCF-7)	1095:1125	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	2	6	from	family	332:337	arg1	algae					288:292	The used algae	279:292	The used algae	279:292	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	2	6	from	family	332:337	arg1	angustifolium					309:321	Sargassum angustifolium	299:321	Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf	299:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	3	7	theme	monomers	523:530	arg1	ratio					514:518	ratio	514:518	ratio of monomers (M/G)	514:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	7	theme	monomers	523:530	arg1	yield					504:508	the extraction yield	489:508	the extraction yield	489:508	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	7	theme	monomers	523:530	arg1	M/G					533:535	M/G	533:535	M/G	533:535	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	0	8	from	angustifolium	62:74	arg1	extraction					20:29	Ultrasound-assisted extraction	0:29	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf	0:102	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	7	9	theme	alginic	1144:1150	arg1	concentration					1157:1169	alginic acid concentration	1144:1169	alginic acid concentration of 250 micrograms per milliliter	1144:1202	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	4	10	theme	cancer	713:718	arg1	cells					720:724	breast cancer cells	706:724	breast cancer cells	706:724	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	7	11	from	0.45	993:996	arg1	addition					953:960	addition	953:960	addition	953:960	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	6	12	theme	extraction	930:939	arg1	process					941:947	the extraction process	926:947	the extraction process	926:947	This shows the effectiveness of ultrasound in facilitating the extraction process.					
36521702	0	13	theme	surface	126:132	arg1	methodology					134:144	response surface methodology	117:144	response surface methodology	117:144	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	4	14	theme	dispersity	659:668	arg1	index					670:674	the poly dispersity index	650:674	the poly dispersity index	650:674	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	7	15	theme	breast	1095:1100	arg1	MCF-7					1120:1124	MCF-7	1120:1124	MCF-7	1120:1124	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	15	theme	breast	1095:1100	arg1	line					1114:1117	breast cancer cell line	1095:1117	breast cancer cell line (MCF-7)	1095:1125	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	2	16	theme	used	283:286	arg1	algae					288:292	The used algae	279:292	The used algae	279:292	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	2	16	theme	used	283:286	arg1	angustifolium					309:321	Sargassum angustifolium	299:321	Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf	299:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	2	17	theme	Gulf	390:393	arg1	coasts					368:373	the coasts	364:373	the coasts of the Persian Gulf	364:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	0	18	theme	response	117:124	arg1	methodology					134:144	response surface methodology	117:144	response surface methodology	117:144	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	5	19	theme	extraction	771:780	arg1	yield					782:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	5	19	theme	extraction	771:780	arg1	%					795:795	46 %	792:795	46 %	792:795	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	4	20	from	effect	612:617	arg1	index					670:674	the poly dispersity index	650:674	the poly dispersity index	650:674	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	4	20	from	effect	612:617	arg1	effects					690:696	cytotoxic effects	680:696	cytotoxic effects against breast cancer cells	680:724	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	5	21	theme	obtained	762:769	arg1	yield					782:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	5	21	theme	obtained	762:769	arg1	%					795:795	46 %	792:795	46 %	792:795	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	6	22	theme	ultrasound	899:908	arg1	effectiveness					882:894	the effectiveness	878:894	the effectiveness of ultrasound	878:908	This shows the effectiveness of ultrasound in facilitating the extraction process.					
36521702	7	23	theme	dispersity	1016:1025	arg1	2.5					1037:1039	2.5	1037:1039	2.5	1037:1039	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	23	theme	dispersity	1016:1025	arg1	index					1027:1031	the minimum poly dispersity index	999:1031	the minimum poly dispersity index	999:1031	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	24	theme	cancer	1102:1107	arg1	MCF-7					1120:1124	MCF-7	1120:1124	MCF-7	1120:1124	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	24	theme	cancer	1102:1107	arg1	line					1114:1117	breast cancer cell line	1095:1117	breast cancer cell line (MCF-7)	1095:1125	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	3	25	theme	temperature	410:420	arg1	effect					400:405	The effect	396:405	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G)	396:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	0	26	theme	Ultrasound-assisted	0:18	arg1	extraction					20:29	Ultrasound-assisted extraction	0:29	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf	0:102	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	1	27	dep	extraction	166:175	arg1	the					162:164	the	162:164	the	162:164	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	1	28	theme	alginic	201:207	arg1	compound					233:240	the most abundant compound	215:240	the most abundant compound	215:240	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	1	28	theme	alginic	201:207	arg1	acid					209:212	alginic acid	201:212	alginic acid	201:212	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	0	29	theme	alginic	34:40	arg1	acid					42:45	alginic acid	34:45	alginic acid	34:45	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	7	30	theme	minimum	1003:1009	arg1	2.5					1037:1039	2.5	1037:1039	2.5	1037:1039	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	30	theme	minimum	1003:1009	arg1	index					1027:1031	the minimum poly dispersity index	999:1031	the minimum poly dispersity index	999:1031	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	4	31	theme	breast	706:711	arg1	cells					720:724	breast cancer cells	706:724	breast cancer cells	706:724	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	1	32	theme	acid	209:212	arg1	characterization					181:196	characterization	181:196	characterization	181:196	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	1	32	theme	acid	209:212	arg1	extraction					166:175	extraction	166:175	extraction	166:175	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	4	33	theme	cytotoxic	680:688	arg1	effects					690:696	cytotoxic effects	680:696	cytotoxic effects against breast cancer cells	680:724	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	3	34	theme	extraction	493:502	arg1	yield					504:508	the extraction yield	489:508	the extraction yield	489:508	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	2	35	theme	Sargassum	299:307	arg1	algae					288:292	The used algae	279:292	The used algae	279:292	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	2	35	theme	Sargassum	299:307	arg1	angustifolium					309:321	Sargassum angustifolium	299:321	Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf	299:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	3	36	theme	solvent	443:449	arg1	ratio					458:462	solvent volume ratio	443:462	solvent volume ratio	443:462	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	4	37	theme	poly	654:657	arg1	index					670:674	the poly dispersity index	650:674	the poly dispersity index	650:674	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	7	38	dep	%	1136:1136	arg1	concentration					1157:1169	alginic acid concentration	1144:1169	alginic acid concentration of 250 micrograms per milliliter	1144:1202	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	39	theme	acid	1152:1155	arg1	concentration					1157:1169	alginic acid concentration	1144:1169	alginic acid concentration of 250 micrograms per milliliter	1144:1202	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	3	40	theme	algae	429:433	arg1	mass					435:438	algae mass	429:438	algae mass to solvent volume ratio	429:462	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	0	41	theme	acid	42:45	arg1	extraction					20:29	Ultrasound-assisted extraction	0:29	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf	0:102	Ultrasound-assisted extraction of alginic acid from Sargassum angustifolium harvested from Persian Gulf shores using response surface methodology.					
36521702	3	42	theme	mass	435:438	arg1	effect					400:405	The effect	396:405	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G)	396:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	43	theme	time	423:426	arg1	effect					400:405	The effect	396:405	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G)	396:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	7	44	theme	minimum	967:973	arg1	0.45					993:996	0.45	993:996	0.45	993:996	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	44	theme	minimum	967:973	arg1	ratio					983:987	the minimum monomer ratio	963:987	the minimum monomer ratio	963:987	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	2	45	theme	algae	348:352	arg1	family					332:337	the family	328:337	the family of brown algae native to the coasts of the Persian Gulf	328:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	5	46	theme	maximum	754:760	arg1	yield					782:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield	750:786	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	5	46	theme	maximum	754:760	arg1	%					795:795	46 %	792:795	46 %	792:795	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	3	47	theme	power	480:484	arg1	effect					400:405	The effect	396:405	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G)	396:536	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	2	48	theme	brown	342:346	arg1	algae					348:352	brown algae	342:352	brown algae native to the coasts of the Persian Gulf	342:393	The used algae were Sargassum angustifolium from the family of brown algae native to the coasts of the Persian Gulf.					
36521702	7	49	theme	monomer	975:981	arg1	0.45					993:996	0.45	993:996	0.45	993:996	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	49	theme	monomer	975:981	arg1	ratio					983:987	the minimum monomer ratio	963:987	the minimum monomer ratio	963:987	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	3	50	theme	composite	573:581	arg1	method					590:595	the central composite design method	561:595	the central composite design method	561:595	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	3	51	theme	volume	451:456	arg1	ratio					458:462	solvent volume ratio	443:462	solvent volume ratio	443:462	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	1	52	theme	abundant	224:231	arg1	compound					233:240	the most abundant compound	215:240	the most abundant compound	215:240	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	1	52	theme	abundant	224:231	arg1	acid					209:212	alginic acid	201:212	alginic acid	201:212	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
36521702	7	53	theme	micrograms	1178:1187	arg1	concentration					1157:1169	alginic acid concentration	1144:1169	alginic acid concentration of 250 micrograms per milliliter	1144:1202	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	5	54	theme	tropical	848:855	arg1	climates					857:864	tropical climates	848:864	tropical climates	848:864	The maximum obtained extraction yield was 46 %, which was higher than those reported for algae in tropical climates.					
36521702	3	55	theme	design	583:588	arg1	method					590:595	the central composite design method	561:595	the central composite design method	561:595	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	4	56	theme	parameters	636:645	arg1	effect					612:617	the effect	608:617	the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells	608:724	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	3	57	theme	central	565:571	arg1	method					590:595	the central composite design method	561:595	the central composite design method	561:595	The effect of temperature, time, algae mass to solvent volume ratio, and ultrasonic power on the extraction yield and ratio of monomers (M/G) was investigated using the central composite design method.					
36521702	4	58	theme	mentioned	626:634	arg1	parameters					636:645	the mentioned parameters	622:645	the mentioned parameters	622:645	Moreover, the effect of the mentioned parameters on the poly dispersity index and cytotoxic effects against breast cancer cells were also investigated.					
36521702	7	59	theme	cell	1109:1112	arg1	MCF-7					1120:1124	MCF-7	1120:1124	MCF-7	1120:1124	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	7	59	theme	cell	1109:1112	arg1	line					1114:1117	breast cancer cell line	1095:1117	breast cancer cell line (MCF-7)	1095:1125	In addition, the minimum monomer ratio was 0.45, the minimum poly dispersity index was 2.5 and the maximum cytotoxicity for using the extract on breast cancer cell line (MCF-7) was 20.3 % (with alginic acid concentration of 250 micrograms per milliliter).					
36521702	1	60	theme	brown	248:252	arg1	algae					254:258	brown algae	248:258	brown algae	248:258	In this study, the extraction and characterization of alginic acid, the most abundant compound among brown algae were investigated.					
35980768	3	0	theme	immune	553:558	arg1	response					560:567	the local inflammatory immune response	530:567	the local inflammatory immune response in horses	530:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	2	1	theme	mucosal	240:246	arg1	integrity					248:256	mucosal integrity	240:256	mucosal integrity that leads to increased intestinal permeability	240:304	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	12	2	theme	detectable	2141:2150	arg1	inflammation					2158:2169	detectable local inflammation	2141:2169	detectable local inflammation	2141:2169	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	3	3	from	response	560:567	arg1	horses					572:577	horses	572:577	horses	572:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	10	4	theme	3-OH	1717:1720	arg1	C16					1722:1724	3-OH C16	1717:1724	3-OH C16	1717:1724	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	4	5	theme	C18	731:733	arg1	acids					741:745	3-OH C14, C16, and C18 fatty acids	712:745	acids	741:745	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	1	6	contain	have	176:179	arg2	consequences					189:200	serious consequences	181:200	serious consequences	181:200	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	1	6	contain	have	176:179	arg1	disturbances					159:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	3	7	from	permeability	513:524	arg1	horses					572:577	horses	572:577	horses	572:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	9	8	theme	administration	1642:1655	arg1	cessation					1622:1630	the cessation	1618:1630	the cessation of barley administration	1618:1655	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	4	9	theme	3-OH	712:715	arg1	C16					722:724	3-OH C14, C16, and C18 fatty acids	712:745	C16	722:724	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	2	10	theme	inflammatory	330:341	arg1	response					350:357	a local inflammatory immune response	322:357	a local inflammatory immune response following alterations of the microbiota, known as dysbiosis	322:417	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	5	11	theme	healthy	868:874	arg1	horses					876:881	9 and 12 healthy horses	859:881	9 and 12 healthy horses	859:881	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	10	12	theme	=	1753:1753	arg1	P					1751:1751	P	1751:1751	P = 0.0114	1751:1760	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	5	13	theme	high	1053:1056	arg1	barley					1073:1078	barley	1073:1078	barley	1073:1078	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	13	theme	high	1053:1056	arg1	levels					1065:1070	high starch levels	1053:1070	high starch levels (barley)	1053:1079	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	10	14	theme	antibiotic	1680:1689	arg1	stressor					1691:1698	the antibiotic stressor	1676:1698	the antibiotic stressor	1676:1698	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	1	15	theme	intestine	141:149	arg1	disturbances					159:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	12	16	theme	d	2030:2030	arg1	translocation					2007:2019	a local translocation	1999:2019	a local translocation of LPS 2 d after the cessation of the stressor treatments	1999:2077	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	5	17	theme	levels	1065:1070	arg1	introduction					1037:1048	abrupt introduction	1030:1048	abrupt introduction of high starch levels (barley) into the diet	1030:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	2	18	theme	integrity	248:256	arg1	loss					232:235	The loss	228:235	The loss of mucosal integrity that leads to increased intestinal permeability	228:304	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	9	19	theme	significant	1492:1502	arg1	increase					1504:1511	a significant increase	1490:1511	a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids	1490:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	10	20	dep	increased	1740:1748	arg1	P					1751:1751	P	1751:1751	P = 0.0114	1751:1760	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	11	21	theme	SIgA	1875:1878	arg1	concentrations					1880:1893	fecal SIgA concentrations	1869:1893	fecal SIgA concentrations for both stressors	1869:1912	No significant day effect was observed for fecal SIgA concentrations for both stressors.					
35980768	5	22	theme	intestinal	906:915	arg1	dysbiosis					917:925	large intestinal dysbiosis	900:925	large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet	900:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	12	23	theme	local	2001:2005	arg1	translocation					2007:2019	a local translocation	1999:2019	a local translocation of LPS 2 d after the cessation of the stressor treatments	1999:2077	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	5	24	theme	introduction	1037:1048	arg1	d					955:955	5 d	953:955	5 d of antibiotic administration (trimethoprim sulfadiazine [TMS])	953:1018	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	24	theme	introduction	1037:1048	arg1	d					1025:1025	5 d	1023:1025	5 d of abrupt introduction of high starch levels (barley) into the diet	1023:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	2	25	theme	increased	272:280	arg1	permeability					293:304	increased intestinal permeability	272:304	increased intestinal permeability	272:304	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	13	26	theme	several	2247:2253	arg1	variations					2265:2274	several bacterial variations	2247:2274	several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis	2247:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	9	27	theme	blood	1516:1520	arg1	concentrations					1522:1535	blood concentrations	1516:1535	blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids	1516:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	9	28	theme	3-OH	1540:1543	arg1	P					1550:1550	P = 0.0125	1550:1559	P = 0.0125	1550:1559	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	9	28	theme	3-OH	1540:1543	arg1	C16					1545:1547	3-OH C16	1540:1547	3-OH C16 (P = 0.0125)	1540:1560	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	14	29	from	loss	2453:2456	arg1	intestine					2492:2500	the large intestine	2482:2500	the large intestine of horses	2482:2510	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	8	30	theme	significant	1337:1347	arg1	interaction					1349:1359	No significant interaction	1334:1359	No significant interaction between day and supplementation, or supplementation effect	1334:1418	No significant interaction between day and supplementation, or supplementation effect were observed for each biomarker.					
35980768	0	31	theme	stress-induced	79:92	arg1	dysbiosis					94:102	stress-induced dysbiosis	79:102	stress-induced dysbiosis	79:102	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	4	32	from	immunoglobulin-A	778:793	arg1	blood					751:755	blood	751:755	blood	751:755	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	4	33	theme	fecal	762:766	arg1	SIgA					796:799	SIgA	796:799	SIgA	796:799	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	4	33	theme	fecal	762:766	arg1	immunoglobulin-A					778:793	fecal secretory immunoglobulin-A	762:793	fecal secretory immunoglobulin-A (SIgA)	762:800	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	5	34	theme	antibiotic	960:969	arg1	[TMS					1013:1016	trimethoprim sulfadiazine [TMS	987:1016	trimethoprim sulfadiazine [TMS	987:1016	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	34	theme	antibiotic	960:969	arg1	administration					971:984	antibiotic administration	960:984	antibiotic administration (trimethoprim sulfadiazine [TMS])	960:1018	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	4	35	theme	fatty	735:739	arg1	acids					741:745	3-OH C14, C16, and C18 fatty acids	712:745	acids	741:745	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	3	36	theme	noninvasive	462:472	arg1	biomarkers					474:483	noninvasive biomarkers	462:483	noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses	462:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	9	37	dep	C16	1545:1547	arg1	acids					1589:1593	fatty acids	1583:1593	fatty acids	1583:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	9	38	theme	C14	1566:1568	arg1	concentrations					1522:1535	blood concentrations	1516:1535	blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids	1516:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	8	39	theme	supplementation	1397:1411	arg1	effect					1413:1418	supplementation effect	1397:1418	supplementation effect	1397:1418	No significant interaction between day and supplementation, or supplementation effect were observed for each biomarker.					
35980768	12	40	theme	intestinal	2108:2117	arg1	permeability					2119:2130	intestinal permeability	2108:2130	intestinal permeability	2108:2130	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	0	41	theme	equine	30:35	arg1	response					67:74	the equine large intestinal inflammatory response	26:74	the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation	26:132	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	13	42	theme	diet-induced	2338:2349	arg1	dysbiosis					2351:2359	antibiotic- and diet-induced dysbiosis	2322:2359	antibiotic- and diet-induced dysbiosis	2322:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	0	43	theme	intestinal	43:52	arg1	response					67:74	the equine large intestinal inflammatory response	26:74	the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation	26:132	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	1	44	theme	Large	135:139	arg1	disturbances					159:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	14	45	theme	large	2486:2490	arg1	intestine					2492:2500	the large intestine	2482:2500	the large intestine of horses	2482:2510	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	9	46	theme	fatty	1583:1587	arg1	acids					1589:1593	fatty acids	1583:1593	fatty acids	1583:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	10	47	theme	TMS	1806:1808	arg1	administration					1810:1823	TMS administration	1806:1823	TMS administration	1806:1823	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	13	48	from	variations	2265:2274	arg1	intestine					2289:2297	the large intestine	2279:2297	the large intestine	2279:2297	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	13	48	from	variations	2265:2274	arg1	features					2310:2317	features	2310:2317	features of antibiotic- and diet-induced dysbiosis	2310:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	5	49	theme	sulfadiazine	1000:1011	arg1	[TMS					1013:1016	trimethoprim sulfadiazine [TMS	987:1016	trimethoprim sulfadiazine [TMS	987:1016	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	49	theme	sulfadiazine	1000:1011	arg1	administration					971:984	antibiotic administration	960:984	antibiotic administration (trimethoprim sulfadiazine [TMS])	960:1018	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	7	50	theme	fecal	1280:1284	arg1	diversity					1296:1304	fecal bacterial diversity	1280:1304	fecal bacterial diversity	1280:1304	Correlations were performed between biomarkers and fecal bacterial diversity, composition, and function.					
35980768	10	51	theme	blood	1701:1705	arg1	levels					1707:1712	blood levels	1701:1712	blood levels of 3-OH C16	1701:1724	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	12	52	theme	antibiotic-	1948:1958	arg1	dysbiosis					1977:1985	both antibiotic- and diet-induced dysbiosis	1943:1985	both antibiotic- and diet-induced dysbiosis	1943:1985	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	14	53	theme	mucosal	2461:2467	arg1	integrity					2469:2477	mucosal integrity	2461:2477	mucosal integrity	2461:2477	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	13	54	theme	antibiotic-	2322:2332	arg1	dysbiosis					2351:2359	antibiotic- and diet-induced dysbiosis	2322:2359	antibiotic- and diet-induced dysbiosis	2322:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	13	55	theme	SIgA	2192:2195	arg1	concentrations					2197:2210	Blood LPS and fecal SIgA concentrations	2172:2210	concentrations	2197:2210	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	2	56	theme	microbiota	388:397	arg1	alterations					369:379	alterations	369:379	alterations	369:379	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	4	57	from	C16	722:724	arg1	blood					751:755	blood	751:755	blood	751:755	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	12	58	theme	diet-induced	1964:1975	arg1	dysbiosis					1977:1985	both antibiotic- and diet-induced dysbiosis	1943:1985	both antibiotic- and diet-induced dysbiosis	1943:1985	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	4	59	theme	mammalian	619:627	arg1	species					629:635	other mammalian species	613:635	other mammalian species	613:635	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	10	60	theme	C16	1722:1724	arg1	levels					1707:1712	blood levels	1701:1712	blood levels of 3-OH C16	1701:1724	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	9	61	theme	C16	1545:1547	arg1	concentrations					1522:1535	blood concentrations	1516:1535	blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids	1516:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	12	62	theme	treatments	2068:2077	arg1	cessation					2042:2050	the cessation	2038:2050	the cessation of the stressor treatments	2038:2077	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	13	63	theme	large	2283:2287	arg1	intestine					2289:2297	the large intestine	2279:2297	the large intestine	2279:2297	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	13	63	theme	large	2283:2287	arg1	features					2310:2317	features	2310:2317	features of antibiotic- and diet-induced dysbiosis	2310:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	9	64	theme	barley	1635:1640	arg1	administration					1642:1655	barley administration	1635:1655	barley administration	1635:1655	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	6	65	dep	either	1108:1113	arg1	control					1115:1121	control	1115:1121	control	1115:1121	Horses were either control or supplemented with Lactobacillus acidophilus, Ligilactobacillus salivarius, and Bifidobacterium lactis.					
35980768	2	66	theme	immune	343:348	arg1	response					350:357	a local inflammatory immune response	322:357	a local inflammatory immune response following alterations of the microbiota, known as dysbiosis	322:417	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	9	67	from	increase	1504:1511	arg1	concentrations					1522:1535	blood concentrations	1516:1535	blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids	1516:1593	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	12	68	theme	stressor	2059:2066	arg1	treatments					2068:2077	the stressor treatments	2055:2077	the stressor treatments	2055:2077	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	2	69	theme	local	324:328	arg1	response					350:357	a local inflammatory immune response	322:357	a local inflammatory immune response following alterations of the microbiota, known as dysbiosis	322:417	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	1	70	theme	horses	220:225	arg1	health					210:215	the health	206:215	the health of horses	206:225	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	4	71	theme	lipopolysaccharides	672:690	arg1	concentrations					654:667	the concentrations	650:667	the concentrations of lipopolysaccharides (LPS)	650:696	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	3	72	theme	inflammatory	540:551	arg1	response					560:567	the local inflammatory immune response	530:567	the local inflammatory immune response in horses	530:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	5	73	theme	starch	1058:1063	arg1	barley					1073:1078	barley	1073:1078	barley	1073:1078	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	73	theme	starch	1058:1063	arg1	levels					1065:1070	high starch levels	1053:1070	high starch levels (barley)	1053:1079	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	9	74	theme	dietary	1472:1478	arg1	stressor					1480:1487	the dietary stressor	1468:1487	the dietary stressor	1468:1487	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	11	75	theme	fecal	1869:1873	arg1	concentrations					1880:1893	fecal SIgA concentrations	1869:1893	fecal SIgA concentrations for both stressors	1869:1912	No significant day effect was observed for fecal SIgA concentrations for both stressors.					
35980768	5	76	theme	large	900:904	arg1	dysbiosis					917:925	large intestinal dysbiosis	900:925	large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet	900:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	77	theme	abrupt	1030:1035	arg1	introduction					1037:1048	abrupt introduction	1030:1048	abrupt introduction of high starch levels (barley) into the diet	1030:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	2	78	theme	intestinal	282:291	arg1	permeability					293:304	increased intestinal permeability	272:304	increased intestinal permeability	272:304	The loss of mucosal integrity that leads to increased intestinal permeability may result from a local inflammatory immune response following alterations of the microbiota, known as dysbiosis.					
35980768	1	79	theme	barrier	151:157	arg1	disturbances					159:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances	135:170	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	12	80	theme	LPS	2024:2026	arg1	d					2030:2030	LPS 2 d	2024:2030	LPS 2 d	2024:2030	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	10	81	theme	first	1772:1776	arg1	day					1778:1780	the first day	1768:1780	the first day to 2 d after the end of TMS administration	1768:1823	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	13	82	theme	bacterial	2255:2263	arg1	variations					2265:2274	several bacterial variations	2247:2274	several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis	2247:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	13	83	theme	fecal	2186:2190	arg1	concentrations					2197:2210	Blood LPS and fecal SIgA concentrations	2172:2210	concentrations	2197:2210	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	4	84	theme	C14	717:719	arg1	C16					722:724	3-OH C14, C16, and C18 fatty acids	712:745	C16	722:724	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	1	85	theme	serious	181:187	arg1	consequences					189:200	serious consequences	181:200	serious consequences	181:200	Large intestine barrier disturbances can have serious consequences for the health of horses.					
35980768	0	86	theme	probiotic	108:116	arg1	supplementation					118:132	probiotic supplementation	108:132	probiotic supplementation	108:132	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	9	87	theme	=	1552:1552	arg1	P					1550:1550	P = 0.0125	1550:1559	P = 0.0125	1550:1559	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	9	87	theme	=	1552:1552	arg1	C16					1545:1547	3-OH C16	1540:1547	3-OH C16 (P = 0.0125)	1540:1560	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	10	88	dep	=	1753:1753	arg1	0.0114					1755:1760	0.0114	1755:1760	0.0114	1755:1760	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	5	89	theme	administration	971:984	arg1	d					955:955	5 d	953:955	5 d of antibiotic administration (trimethoprim sulfadiazine [TMS])	953:1018	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	89	theme	administration	971:984	arg1	d					1025:1025	5 d	1023:1025	5 d of abrupt introduction of high starch levels (barley) into the diet	1023:1093	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	4	90	theme	secretory	768:776	arg1	SIgA					796:799	SIgA	796:799	SIgA	796:799	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	4	90	theme	secretory	768:776	arg1	immunoglobulin-A					778:793	fecal secretory immunoglobulin-A	762:793	fecal secretory immunoglobulin-A (SIgA)	762:800	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	11	91	theme	day	1841:1843	arg1	effect					1845:1850	No significant day effect	1826:1850	No significant day effect	1826:1850	No significant day effect was observed for fecal SIgA concentrations for both stressors.					
35980768	14	92	from	dysbiosis	2435:2443	arg1	intestine					2492:2500	the large intestine	2482:2500	the large intestine of horses	2482:2510	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	9	93	dep	d	1610:1610	arg1	cessation					1622:1630	the cessation	1618:1630	the cessation of barley administration	1618:1655	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	13	94	theme	Blood	2172:2176	arg1	LPS					2178:2180	Blood LPS and fecal SIgA concentrations	2172:2210	LPS	2178:2180	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	4	95	theme	other	613:617	arg1	species					629:635	other mammalian species	613:635	other mammalian species	613:635	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	12	96	theme	local	2152:2156	arg1	inflammation					2158:2169	detectable local inflammation	2141:2169	detectable local inflammation	2141:2169	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	3	97	theme	intestinal	502:511	arg1	permeability					513:524	the intestinal permeability	498:524	the intestinal permeability	498:524	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	0	98	theme	large	37:41	arg1	response					67:74	the equine large intestinal inflammatory response	26:74	the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation	26:132	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	14	99	theme	horses	2505:2510	arg1	intestine					2492:2500	the large intestine	2482:2500	the large intestine of horses	2482:2510	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	9	100	theme	=	1573:1573	arg1	C14					1566:1568	C14	1566:1568	C14 (P = 0.0252)	1566:1581	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	9	100	theme	=	1573:1573	arg1	P					1571:1571	P = 0.0252	1571:1580	P = 0.0252	1571:1580	However, with the dietary stressor, a significant increase in blood concentrations of 3-OH C16 (P = 0.0125) and C14 (P = 0.0252) fatty acids was measured 2 d after the cessation of barley administration.					
35980768	11	101	theme	significant	1829:1839	arg1	effect					1845:1850	No significant day effect	1826:1850	No significant day effect	1826:1850	No significant day effect was observed for fecal SIgA concentrations for both stressors.					
35980768	0	102	theme	inflammatory	54:65	arg1	response					67:74	the equine large intestinal inflammatory response	26:74	the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation	26:132	Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.					
35980768	13	103	theme	dysbiosis	2351:2359	arg1	intestine					2289:2297	the large intestine	2279:2297	the large intestine	2279:2297	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	13	103	theme	dysbiosis	2351:2359	arg1	features					2310:2317	features	2310:2317	features of antibiotic- and diet-induced dysbiosis	2310:2359	Blood LPS and fecal SIgA concentrations were significantly correlated with several bacterial variations in the large intestine, which are features of antibiotic- and diet-induced dysbiosis.					
35980768	7	104	theme	bacterial	1286:1294	arg1	diversity					1296:1304	fecal bacterial diversity	1280:1304	fecal bacterial diversity	1280:1304	Correlations were performed between biomarkers and fecal bacterial diversity, composition, and function.					
35980768	10	105	theme	administration	1810:1823	arg1	end					1799:1801	the end	1795:1801	the end of TMS administration	1795:1823	Furthermore, with the antibiotic stressor, blood levels of 3-OH C16 progressively increased (P = 0.0114) from the first day to 2 d after the end of TMS administration.					
35980768	12	106	theme	permeability	2119:2130	arg1	impairment					2094:2103	an impairment	2091:2103	an impairment of intestinal permeability	2091:2130	These results indicate that both antibiotic- and diet-induced dysbiosis resulted in a local translocation of LPS 2 d after the cessation of the stressor treatments, suggesting an impairment of intestinal permeability, without detectable local inflammation.					
35980768	3	107	theme	local	534:538	arg1	response					560:567	the local inflammatory immune response	530:567	the local inflammatory immune response in horses	530:577	Therefore, our research aimed to identify noninvasive biomarkers for studying the intestinal permeability and the local inflammatory immune response in horses.					
35980768	4	108	from	acids	741:745	arg1	blood					751:755	blood	751:755	blood	751:755	Regarding the biomarkers used in other mammalian species, we measured the concentrations of lipopolysaccharides (LPS), reflected by 3-OH C14, C16, and C18 fatty acids, in blood, and fecal secretory immunoglobulin-A (SIgA).					
35980768	5	109	theme	trimethoprim	987:998	arg1	[TMS					1013:1016	trimethoprim sulfadiazine [TMS	987:1016	trimethoprim sulfadiazine [TMS	987:1016	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	5	109	theme	trimethoprim	987:998	arg1	administration					971:984	antibiotic administration	960:984	antibiotic administration (trimethoprim sulfadiazine [TMS])	960:1018	These biomarkers were evaluated in two trials including 9 and 12 healthy horses, which developed large intestinal dysbiosis experimentally induced by 5 d of antibiotic administration (trimethoprim sulfadiazine [TMS]) or 5 d of abrupt introduction of high starch levels (barley) into the diet.					
35980768	14	110	theme	integrity	2469:2477	arg1	dysbiosis					2435:2443	dysbiosis	2435:2443	dysbiosis	2435:2443	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
35980768	14	110	theme	integrity	2469:2477	arg1	loss					2453:2456	the loss	2449:2456	the loss of mucosal integrity in the large intestine of horses	2449:2510	These findings support the hypothesis that a relationship exists between dysbiosis and the loss of mucosal integrity in the large intestine of horses.					
36414077	0	0	theme	conductive	78:87	arg1	hydrogels					89:97	nanofiber composite ionic conductive hydrogels	52:97	nanofiber composite ionic conductive hydrogels for strain sensors	52:116	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	5	1	theme	probing	1149:1155	arg1	motions					1163:1169	probing human motions	1149:1169	probing human motions	1149:1169	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	2	2	used	used	390:393	arg2	CNFs					379:382	CNFs	379:382	CNFs	379:382	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	2	used	used	390:393	arg2	nanofibers					367:376	PVA/cellulose nanofibers	353:376	PVA/cellulose nanofibers (CNFs)	353:383	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	2	used	used	390:393	arg2	substrate					408:416	composite substrate	398:416	composite substrate	398:416	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	3	theme	PVA/cellulose	353:365	arg1	substrate					408:416	composite substrate	398:416	composite substrate	398:416	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	3	theme	PVA/cellulose	353:365	arg1	CNFs					379:382	CNFs	379:382	CNFs	379:382	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	3	theme	PVA/cellulose	353:365	arg1	nanofibers					367:376	PVA/cellulose nanofibers	353:376	PVA/cellulose nanofibers (CNFs)	353:383	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	4	4	theme	insufficient	1058:1069	arg1	Fe3+					1071:1074	insufficient Fe3+	1058:1074	insufficient Fe3+	1058:1074	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	1	5	theme	nanoparticles	268:280	arg1	application					238:248	final application	232:248	final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	232:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	0	6	theme	ionic	72:76	arg1	hydrogels					89:97	nanofiber composite ionic conductive hydrogels	52:97	nanofiber composite ionic conductive hydrogels for strain sensors	52:116	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	5	7	theme	human	1157:1161	arg1	motions					1163:1169	probing human motions	1149:1169	probing human motions	1149:1169	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	3	8	theme	physical	664:671	arg1	crosslinks					673:682	physical crosslinks	664:682	physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks	664:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	1	9	theme	effective	163:171	arg1	strategy					173:180	an effective strategy	160:180	an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	160:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	10	theme	reinforced	282:291	arg1	poly					293:296	reinforced poly	282:296	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	10	theme	reinforced	282:291	arg1	alcohol					304:310	vinyl alcohol	298:310	vinyl alcohol	298:310	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	10	theme	reinforced	282:291	arg1	PVA					314:316	PVA	314:316	PVA	314:316	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	3	11	theme	boronic	555:561	arg1	bonds					578:582	boronic ester covalent bonds	555:582	boronic ester covalent bonds only	555:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	12	theme	chemical	737:744	arg1	crosslinks					746:755	chemical crosslinks	737:755	chemical crosslinks	737:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	0	13	link	cross-linked	9:20	arg1	poly					22:25	Multiply cross-linked poly	0:25	Multiply cross-linked poly(vinyl alcohol)	0:40	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	0	13	link	cross-linked	9:20	arg1	alcohol					33:39	vinyl alcohol	27:39	vinyl alcohol	27:39	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	3	14	theme	ester	563:567	arg1	bonds					578:582	boronic ester covalent bonds	555:582	boronic ester covalent bonds only	555:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	6	15	dep	structure	1231:1239	arg1	the					1219:1221	the	1219:1221	the	1219:1221	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	3	16	theme	crosslinks	746:755	arg1	crystallites					692:703	PVA crystallites	688:703	PVA crystallites	688:703	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	16	theme	crosslinks	746:755	arg1	kinds					728:732	aforementioned two kinds	709:732	aforementioned two kinds of chemical crosslinks	709:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	6	17	theme	multiple	1302:1309	arg1	crosslinks					1311:1320	multiple crosslinks	1302:1320	multiple crosslinks	1302:1320	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	4	18	theme	triple	792:797	arg1	crosslinks					799:808	triple crosslinks	792:808	triple crosslinks	792:808	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	6	19	theme	composite	1277:1285	arg1	hydrogels					1287:1295	PVA/CNF composite hydrogels	1269:1295	PVA/CNF composite hydrogels with multiple crosslinks	1269:1320	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	0	20	theme	strain	103:108	arg1	sensors					110:116	strain sensors	103:116	strain sensors	103:116	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	5	21	theme	strain	1131:1136	arg1	sensor					1138:1143	strain sensor	1131:1143	strain sensor for probing human motions	1131:1169	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	3	22	with	types	483:487	arg1	bonding					629:635	additional metal coordination bonding	599:635	additional metal coordination bonding	599:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	0	23	theme	cross-linked	9:20	arg1	poly					22:25	Multiply cross-linked poly	0:25	Multiply cross-linked poly(vinyl alcohol)	0:40	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	0	23	theme	cross-linked	9:20	arg1	alcohol					33:39	vinyl alcohol	27:39	vinyl alcohol	27:39	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	2	24	theme	conductive	437:446	arg1	hydrogels					448:456	ionic conductive hydrogels	431:456	ionic conductive hydrogels	431:456	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	1	25	theme	vinyl	298:302	arg1	poly					293:296	reinforced poly	282:296	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	25	theme	vinyl	298:302	arg1	alcohol					304:310	vinyl alcohol	298:310	vinyl alcohol	298:310	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	5	26	theme	As-optimized	1077:1088	arg1	hydrogel					1107:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	1	27	theme	mechanical	193:202	arg1	properties					204:213	mechanical properties	193:213	mechanical properties	193:213	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	2	28	theme	ionic	431:435	arg1	hydrogels					448:456	ionic conductive hydrogels	431:456	ionic conductive hydrogels	431:456	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	4	29	theme	mechanical	823:832	arg1	strength					834:841	superior mechanical strength	814:841	superior mechanical strength	814:841	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	3	30	theme	covalent	569:576	arg1	bonds					578:582	boronic ester covalent bonds	555:582	boronic ester covalent bonds only	555:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	6	31	theme	PVA/CNF	1269:1275	arg1	hydrogels					1287:1295	PVA/CNF composite hydrogels	1269:1295	PVA/CNF composite hydrogels with multiple crosslinks	1269:1320	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	4	32	with	sample	780:785	arg1	crosslinks					799:808	triple crosslinks	792:808	triple crosslinks	792:808	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	6	33	theme	interesting	1194:1204	arg1	insight					1206:1212	an interesting insight	1191:1212	an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks	1191:1320	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	5	34	theme	ionic	1090:1094	arg1	hydrogel					1107:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	6	35	theme	network	1223:1229	arg1	structure					1231:1239	network structure	1223:1239	network structure	1223:1239	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	3	36	with	coexistence	649:659	arg1	bonding					629:635	additional metal coordination bonding	599:635	additional metal coordination bonding	599:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	37	theme	crosslinks	507:516	arg1	coexistence					649:659	coexistence	649:659	coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks	649:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	37	theme	crosslinks	507:516	arg1	crosslinking					538:549	chemical crosslinking	529:549	chemical crosslinking via boronic ester covalent bonds only	529:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	37	theme	crosslinks	507:516	arg1	types					483:487	Three types	477:487	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding	477:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	5	38	theme	conductive	1096:1105	arg1	hydrogel					1107:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel	1077:1114	As-optimized ionic conductive hydrogel is suitable as strain sensor for probing human motions.					
36414077	3	39	theme	additional	599:608	arg1	bonding					629:635	additional metal coordination bonding	599:635	additional metal coordination bonding	599:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	2	40	theme	composite	398:406	arg1	nanofibers					367:376	PVA/cellulose nanofibers	353:376	PVA/cellulose nanofibers (CNFs)	353:383	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	2	40	theme	composite	398:406	arg1	substrate					408:416	composite substrate	398:416	composite substrate	398:416	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	0	41	theme	vinyl	27:31	arg1	poly					22:25	Multiply cross-linked poly	0:25	Multiply cross-linked poly(vinyl alcohol)	0:40	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	0	41	theme	vinyl	27:31	arg1	alcohol					33:39	vinyl alcohol	27:39	vinyl alcohol	27:39	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	4	42	theme	double-network	947:960	arg1	structure					962:970	double-network structure	947:970	double-network structure	947:970	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	3	43	theme	metal	610:614	arg1	bonding					629:635	additional metal coordination bonding	599:635	additional metal coordination bonding	599:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	4	44	theme	polydopamine/Fe3+	878:894	arg1	ratio					896:900	the polydopamine/Fe3+ ratio	874:900	the polydopamine/Fe3+ ratio	874:900	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	2	45	theme	strain	462:467	arg1	sensor					469:474	strain sensor	462:474	strain sensor	462:474	In this work, PVA/cellulose nanofibers (CNFs) were used as composite substrate to fabricate ionic conductive hydrogels for strain sensor.					
36414077	1	46	dep	strategy	173:180	arg1	improve					185:191	improve	185:191	to improve mechanical properties	182:213	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	46	dep	strategy	173:180	arg1	diversify					222:230	diversify	222:230	to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	219:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	47	theme	physical	319:326	arg1	hydrogels					328:336	physical hydrogels	319:336	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	48	dep	poly	293:296	arg1	hydrogels					328:336	physical hydrogels	319:336	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	6	49	theme	property	1245:1252	arg1	regulation					1254:1263	property regulation	1245:1263	property regulation	1245:1263	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	3	50	theme	characteristic	492:505	arg1	crosslinks					507:516	characteristic crosslinks	492:516	characteristic crosslinks	492:516	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	4	51	theme	superior	814:821	arg1	strength					834:841	superior mechanical strength	814:841	superior mechanical strength	814:841	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	4	52	theme	final	921:925	arg1	performance					927:937	final performance	921:937	final performance	921:937	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	3	53	theme	PVA	688:690	arg1	crystallites					692:703	PVA crystallites	688:703	PVA crystallites	688:703	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	1	54	theme	multiple	128:135	arg1	crosslinks					146:155	multiple chemical crosslinks	128:155	multiple chemical crosslinks	128:155	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	55	theme	final	232:236	arg1	application					238:248	final application	232:248	final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	232:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	56	dep	nanoparticles	268:280	arg1	poly					293:296	reinforced poly	282:296	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	56	dep	nanoparticles	268:280	arg1	alcohol					304:310	vinyl alcohol	298:310	vinyl alcohol	298:310	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	56	dep	nanoparticles	268:280	arg1	PVA					314:316	PVA	314:316	PVA	314:316	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	1	57	theme	chemical	137:144	arg1	crosslinks					146:155	multiple chemical crosslinks	128:155	multiple chemical crosslinks	128:155	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
36414077	0	58	theme	composite	62:70	arg1	hydrogels					89:97	nanofiber composite ionic conductive hydrogels	52:97	nanofiber composite ionic conductive hydrogels for strain sensors	52:116	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	3	59	theme	crosslinks	673:682	arg1	coexistence					649:659	coexistence	649:659	coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks	649:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	59	theme	crosslinks	673:682	arg1	crosslinking					538:549	chemical crosslinking	529:549	chemical crosslinking via boronic ester covalent bonds only	529:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	59	theme	crosslinks	673:682	arg1	types					483:487	Three types	477:487	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding	477:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	3	60	theme	coordination	616:627	arg1	bonding					629:635	additional metal coordination bonding	599:635	additional metal coordination bonding	599:635	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	6	61	with	hydrogels	1287:1295	arg1	crosslinks					1311:1320	multiple crosslinks	1302:1320	multiple crosslinks	1302:1320	This work provides an interesting insight into the network structure and property regulation for PVA/CNF composite hydrogels with multiple crosslinks.					
36414077	0	62	theme	nanofiber	52:60	arg1	hydrogels					89:97	nanofiber composite ionic conductive hydrogels	52:97	nanofiber composite ionic conductive hydrogels for strain sensors	52:116	Multiply cross-linked poly(vinyl alcohol)/cellulose nanofiber composite ionic conductive hydrogels for strain sensors.					
36414077	3	63	theme	aforementioned	709:722	arg1	kinds					728:732	aforementioned two kinds	709:732	aforementioned two kinds of chemical crosslinks	709:755	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	4	64	contain	has	810:812	arg1	sample					780:785	The sample	776:785	The sample with triple crosslinks	776:808	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	4	64	contain	has	810:812	arg2	resistance					847:856	resistance	847:856	resistance to fatigue	847:867	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	4	64	contain	has	810:812	arg2	strength					834:841	superior mechanical strength	814:841	superior mechanical strength	814:841	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	3	65	theme	chemical	529:536	arg1	crosslinking					538:549	chemical crosslinking	529:549	chemical crosslinking via boronic ester covalent bonds only	529:587	Three types of characteristic crosslinks, including chemical crosslinking via boronic ester covalent bonds only, and with additional metal coordination bonding, as well as coexistence of physical crosslinks via PVA crystallites and aforementioned two kinds of chemical crosslinks, were constructed.					
36414077	4	66	theme	Fe3+	1071:1074	arg1	case					1050:1053	the case	1046:1053	the case of insufficient Fe3+	1046:1074	The sample with triple crosslinks has superior mechanical strength and resistance to fatigue, and the polydopamine/Fe3+ ratio act as key to tune final performance because double-network structure prefers to form as Fe3+ is superfluous, while dual-crosslink one forms in the case of insufficient Fe3+.					
36414077	1	67	theme	polysaccharide	253:266	arg1	nanoparticles					268:280	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels	253:336	Building multiple chemical crosslinks is an effective strategy to improve mechanical properties and to diversify final application of polysaccharide nanoparticles reinforced poly(vinyl alcohol) (PVA) physical hydrogels.					
37030175	17	0	theme	endplates	2508:2516	arg1	significance					2454:2465	the significance	2450:2465	the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs	2450:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	14	1	from	permeability	1923:1934	arg1	tissues					1907:1913	intervertebral soft tissues	1887:1913	intervertebral soft tissues	1887:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	6	2	theme	residual	844:851	arg1	responses					880:888	the immediate (or residual), short-term and long-term responses	826:888	the immediate (or residual), short-term and long-term responses of these tests	826:903	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	3	3	theme	discs	525:529	arg1	responses					487:495	the quasi-static responses	470:495	the quasi-static responses of healthy and degenerative discs	470:529	The goal of this study is to quantitatively analyze the quasi-static responses of healthy and degenerative discs.					
37030175	8	4	theme	short-term	1209:1218	arg1	response					1220:1227	the short-term response	1205:1227	the short-term response	1205:1227	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	7	5	from	modulus	1018:1024	arg1	pulposus					993:1000	the nucleus pulposus	981:1000	the nucleus pulposus	981:1000	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	7	6	dep	RESULTS	906:912	arg1	show					933:936	show	933:936	show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration	933:1051	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	14	7	theme	fluid-dependent	2000:2014	arg1	responses					2029:2037	the fluid-dependent viscoelastic responses	1996:2037	the fluid-dependent viscoelastic responses of intervertebral discs	1996:2061	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	2	8	theme	degeneration	321:332	arg1	effects					310:316	the effects	306:316	the effects of degeneration on the quasi-static biomechanical responses of discs	306:385	Up to the present, the effects of degeneration on the quasi-static biomechanical responses of discs have not been well understood.					
37030175	1	9	theme	changes	229:235	arg1	dependent					212:220	dependent	212:220	dependent	212:220	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	16	10	theme	modulus	2275:2281	arg1	changes					2252:2258	the changes	2248:2258	the changes of the initial modulus	2248:2281	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	9	11	theme	degenerated	1280:1290	arg1	permeability					1292:1303	degenerated permeability	1280:1303	degenerated permeability in cartilage endplates	1280:1326	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	1	12	theme	tissue	240:245	arg1	ratio					259:263	tissue composition ratio	240:263	tissue composition ratio	240:263	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	14	13	theme	intervertebral	1887:1900	arg1	tissues					1907:1913	intervertebral soft tissues	1887:1913	intervertebral soft tissues	1887:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	7	14	from	pressure	969:976	arg1	pulposus					993:1000	the nucleus pulposus	981:1000	the nucleus pulposus	981:1000	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	14	15	theme	endplates	1949:1957	arg1	content					1855:1861	The content	1851:1861	The content of glycosaminoglycan in intervertebral soft tissues	1851:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	15	theme	endplates	1949:1957	arg1	CONCLUSIONS					1839:1849	CONCLUSIONS	1839:1849	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates	1839:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	15	theme	endplates	1949:1957	arg1	permeability					1923:1934	the permeability	1919:1934	the permeability of cartilage endplates	1919:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	1	16	from	changes	229:235	arg1	ratio					259:263	tissue composition ratio	240:263	tissue composition ratio	240:263	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	1	16	from	changes	229:235	arg1	structure					276:284	tissue structure	269:284	tissue structure	269:284	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	12	17	theme	short-term	1587:1596	arg1	responses					1598:1606	Both the residual and short-term responses	1565:1606	responses	1598:1606	Both the residual and short-term responses vary monotonically with degeneration.					
37030175	11	18	theme	response	1520:1527	arg1	%					1509:1509	approximately 31%	1493:1509	approximately 31% of total response	1493:1527	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	11	18	theme	response	1520:1527	arg1	response					1520:1527	total response	1514:1527	total response	1514:1527	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	13	19	theme	rheologic	1768:1776	arg1	models					1778:1783	the rheologic models	1764:1783	the rheologic models	1764:1783	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	0	20	theme	healthy	82:88	arg1	discs					122:126	healthy and degenerative intervertebral discs	82:126	healthy and degenerative intervertebral discs	82:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	5	21	theme	quasi-static	640:651	arg1	free-swelling					683:695	the free-swelling	679:695	the free-swelling	679:695	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	21	theme	quasi-static	640:651	arg1	creep					709:713	creep	709:713	creep	709:713	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	21	theme	quasi-static	640:651	arg1	stress-relaxation					719:735	stress-relaxation	719:735	stress-relaxation	719:735	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	21	theme	quasi-static	640:651	arg1	protocols					658:666	Four quasi-static test protocols	635:666	Four quasi-static test protocols	635:666	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	21	theme	quasi-static	640:651	arg1	slow-ramp					698:706	slow-ramp	698:706	slow-ramp	698:706	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	1	22	theme	discs	189:193	arg1	degeneration					158:169	The degeneration	154:169	The degeneration of intervertebral discs	154:193	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	17	23	theme	boundary	2378:2385	arg1	conditions					2387:2396	boundary conditions	2378:2396	boundary conditions	2378:2396	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	17	24	theme	computational	2299:2311	arg1	models					2313:2318	existing computational models	2290:2318	existing computational models	2290:2318	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	0	25	theme	degenerative	94:105	arg1	discs					122:126	healthy and degenerative intervertebral discs	82:126	healthy and degenerative intervertebral discs	82:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	13	26	from	permeability	1825:1836	arg1	models					1778:1783	the rheologic models	1764:1783	the rheologic models	1764:1783	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	8	27	theme	discs	1083:1087	arg1	test					1075:1078	the free-swelling test	1057:1078	the free-swelling test of discs possessing healthy cartilage endplates	1057:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	12	28	theme	residual	1574:1581	arg1	responses					1598:1606	Both the residual and short-term responses	1565:1606	responses	1598:1606	Both the residual and short-term responses vary monotonically with degeneration.					
37030175	13	29	theme	time	1746:1749	arg1	constants					1751:1759	the engineering equilibrium time constants	1718:1759	the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability	1718:1836	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	1	30	dep	BACKGROUND	129:138	arg1	degeneration					158:169	The degeneration	154:169	The degeneration of intervertebral discs	154:193	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	6	31	theme	double	759:764	arg1	Voigt					766:770	double Voigt	759:770	double Voigt	759:770	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	0	32	theme	discs	122:126	arg1	behaviors					69:77	the quasi-static biomechanical behaviors	38:77	the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	38:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	8	33	theme	healthy	1100:1106	arg1	endplates					1118:1126	healthy cartilage endplates	1100:1126	healthy cartilage endplates	1100:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	11	34	theme	stress	1464:1469	arg1	contribution					1471:1482	the long-term stress contribution	1450:1482	the long-term stress contribution	1450:1482	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	11	34	theme	stress	1464:1469	arg1	independent					1536:1546	independent	1536:1546	independent	1536:1546	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	3	35	theme	study	435:439	arg1	goal					422:425	The goal	418:425	The goal of this study	418:439	The goal of this study is to quantitatively analyze the quasi-static responses of healthy and degenerative discs.					
37030175	15	36	theme	responses	2126:2134	arg1	proportions					2078:2088	The component proportions	2064:2088	The component proportions of the fluid-dependent viscoelastic responses	2064:2134	The component proportions of the fluid-dependent viscoelastic responses depend also strongly on test protocols.					
37030175	14	37	theme	soft	1902:1905	arg1	tissues					1907:1913	intervertebral soft tissues	1887:1913	intervertebral soft tissues	1887:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	3	38	theme	quasi-static	474:485	arg1	responses					487:495	the quasi-static responses	470:495	the quasi-static responses of healthy and degenerative discs	470:529	The goal of this study is to quantitatively analyze the quasi-static responses of healthy and degenerative discs.					
37030175	0	39	theme	biphasic	17:24	arg1	analysis					26:33	A swelling-based biphasic analysis	0:33	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	0:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	8	40	theme	simulation	1129:1138	arg1	results					1140:1146	simulation results	1129:1146	simulation results	1129:1146	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	15	41	theme	test	2160:2163	arg1	protocols					2165:2173	test protocols	2160:2173	test protocols	2160:2173	The component proportions of the fluid-dependent viscoelastic responses depend also strongly on test protocols.					
37030175	17	42	theme	degenerated	2565:2575	arg1	discs					2577:2581	degenerated discs	2565:2581	degenerated discs	2565:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	13	43	theme	engineering	1722:1732	arg1	constants					1751:1759	the engineering equilibrium time constants	1718:1759	the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability	1718:1836	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	4	44	theme	biphasic	545:552	arg1	models					584:589	Four biphasic swelling-based finite element models	540:589	METHODS Four biphasic swelling-based finite element models	532:589	METHODS Four biphasic swelling-based finite element models are developed and quantitatively validated.					
37030175	13	45	theme	glycosaminoglycan	1668:1684	arg1	content					1686:1692	the glycosaminoglycan content	1664:1692	the glycosaminoglycan content	1664:1692	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	10	46	theme	deformation	1365:1375	arg1	deformation					1365:1375	the deformation	1361:1375	the deformation	1361:1375	For the creep test, over 50% of the deformation is contributed by the long-term response.					
37030175	10	46	theme	deformation	1365:1375	arg1	%					1356:1356	over 50%	1349:1356	over 50% of the deformation	1349:1375	For the creep test, over 50% of the deformation is contributed by the long-term response.					
37030175	0	47	theme	quasi-static	42:53	arg1	behaviors					69:77	the quasi-static biomechanical behaviors	38:77	the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	38:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	16	48	from	responsible	2232:2242	arg1	test					2193:2196	the slow-ramp test	2179:2196	the slow-ramp test	2179:2196	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	17	49	theme	disc	2365:2368	arg1	height					2370:2375	disc height	2365:2375	disc height	2365:2375	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	4	50	theme	finite	569:574	arg1	models					584:589	Four biphasic swelling-based finite element models	540:589	METHODS Four biphasic swelling-based finite element models	532:589	METHODS Four biphasic swelling-based finite element models are developed and quantitatively validated.					
37030175	2	51	theme	quasi-static	341:352	arg1	responses					368:376	the quasi-static biomechanical responses	337:376	the quasi-static biomechanical responses of discs	337:385	Up to the present, the effects of degeneration on the quasi-static biomechanical responses of discs have not been well understood.					
37030175	7	52	theme	swelling-induced	952:967	arg1	pressure					969:976	the swelling-induced pressure	948:976	the swelling-induced pressure in the nucleus pulposus	948:1000	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	1	53	theme	composition	247:257	arg1	ratio					259:263	tissue composition ratio	240:263	tissue composition ratio	240:263	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	14	54	theme	intervertebral	2042:2055	arg1	discs					2057:2061	intervertebral discs	2042:2061	intervertebral discs	2042:2061	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	17	55	theme	composition	2482:2492	arg1	significance					2454:2465	the significance	2450:2465	the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs	2450:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	17	56	from	significance	2454:2465	arg1	behaviors					2552:2560	the biomechanical behaviors	2534:2560	the biomechanical behaviors of degenerated discs	2534:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	6	57	theme	Maxwell	783:789	arg1	models					791:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	17	58	theme	cartilage	2498:2506	arg1	endplates					2508:2516	cartilage endplates	2498:2516	cartilage endplates	2498:2516	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	2	59	theme	discs	381:385	arg1	responses					368:376	the quasi-static biomechanical responses	337:376	the quasi-static biomechanical responses of discs	337:385	Up to the present, the effects of degeneration on the quasi-static biomechanical responses of discs have not been well understood.					
37030175	15	60	theme	fluid-dependent	2097:2111	arg1	responses					2126:2134	the fluid-dependent viscoelastic responses	2093:2134	the fluid-dependent viscoelastic responses	2093:2134	The component proportions of the fluid-dependent viscoelastic responses depend also strongly on test protocols.					
37030175	16	61	from	test	2193:2196	arg1	responsible					2232:2242	responsible	2232:2242	responsible	2232:2242	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	16	61	from	test	2193:2196	arg1	content					2221:2227	the glycosaminoglycan content	2199:2227	the glycosaminoglycan content	2199:2227	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	8	62	theme	strain	1180:1185	arg1	strain					1180:1185	the total strain	1170:1185	the total strain	1170:1185	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	8	62	theme	strain	1180:1185	arg1	%					1165:1165	over 80%	1158:1165	over 80% of the total strain	1158:1185	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	15	63	theme	component	2068:2076	arg1	proportions					2078:2088	The component proportions	2064:2088	The component proportions of the fluid-dependent viscoelastic responses	2064:2134	The component proportions of the fluid-dependent viscoelastic responses depend also strongly on test protocols.					
37030175	7	64	theme	Simulation	914:923	arg1	results					925:931	Simulation results	914:931	Simulation results	914:931	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	9	65	from	permeability	1292:1303	arg1	endplates					1318:1326	cartilage endplates	1308:1326	cartilage endplates	1308:1326	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	6	66	used	used	810:813	arg2	models					791:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	11	67	theme	stress-relaxation	1426:1442	arg1	test					1444:1447	the stress-relaxation test	1422:1447	the stress-relaxation test	1422:1447	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	9	68	theme	long-term	1234:1242	arg1	dominant					1256:1263	dominant	1256:1263	dominant	1256:1263	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	9	68	theme	long-term	1234:1242	arg1	response					1244:1251	The long-term response	1230:1251	The long-term response	1230:1251	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	14	69	theme	viscoelastic	2016:2027	arg1	responses					2029:2037	the fluid-dependent viscoelastic responses	1996:2037	the fluid-dependent viscoelastic responses of intervertebral discs	1996:2061	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	70	from	content	1855:1861	arg1	tissues					1907:1913	intervertebral soft tissues	1887:1913	intervertebral soft tissues	1887:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	6	71	theme	immediate	830:838	arg1	responses					880:888	the immediate (or residual), short-term and long-term responses	826:888	the immediate (or residual), short-term and long-term responses of these tests	826:903	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	8	72	theme	free-swelling	1061:1073	arg1	test					1075:1078	the free-swelling test	1057:1078	the free-swelling test of discs possessing healthy cartilage endplates	1057:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	16	73	theme	initial	2267:2273	arg1	modulus					2275:2281	the initial modulus	2263:2281	the initial modulus	2263:2281	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	14	74	dep	CONCLUSIONS	1839:1849	arg1	content					1855:1861	The content	1851:1861	The content of glycosaminoglycan in intervertebral soft tissues	1851:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	74	dep	CONCLUSIONS	1839:1849	arg1	CONCLUSIONS					1839:1849	CONCLUSIONS	1839:1849	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates	1839:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	74	dep	CONCLUSIONS	1839:1849	arg1	permeability					1923:1934	the permeability	1919:1934	the permeability of cartilage endplates	1919:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	2	75	theme	biomechanical	354:366	arg1	responses					368:376	the quasi-static biomechanical responses	337:376	the quasi-static biomechanical responses of discs	337:385	Up to the present, the effects of degeneration on the quasi-static biomechanical responses of discs have not been well understood.					
37030175	14	76	theme	critical	1967:1974	arg1	factors					1976:1982	two critical factors	1963:1982	two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs	1963:2061	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	76	theme	critical	1967:1974	arg1	CONCLUSIONS					1839:1849	CONCLUSIONS	1839:1849	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates	1839:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	17	77	theme	current	2426:2432	arg1	work					2434:2437	the current work	2422:2437	the current work	2422:2437	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	13	78	theme	determining	1799:1809	arg1	factor					1811:1816	the determining factor	1795:1816	the determining factor	1795:1816	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	13	78	theme	determining	1799:1809	arg1	permeability					1825:1836	the permeability	1821:1836	the permeability	1821:1836	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	9	79	theme	cartilage	1308:1316	arg1	endplates					1318:1326	cartilage endplates	1308:1326	cartilage endplates	1308:1326	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	5	80	theme	test	653:656	arg1	free-swelling					683:695	the free-swelling	679:695	the free-swelling	679:695	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	80	theme	test	653:656	arg1	creep					709:713	creep	709:713	creep	709:713	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	80	theme	test	653:656	arg1	stress-relaxation					719:735	stress-relaxation	719:735	stress-relaxation	719:735	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	80	theme	test	653:656	arg1	protocols					658:666	Four quasi-static test protocols	635:666	Four quasi-static test protocols	635:666	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	5	80	theme	test	653:656	arg1	slow-ramp					698:706	slow-ramp	698:706	slow-ramp	698:706	Four quasi-static test protocols, including the free-swelling, slow-ramp, creep and stress-relaxation, are implemented.					
37030175	14	81	theme	cartilage	1939:1947	arg1	endplates					1949:1957	cartilage endplates	1939:1957	cartilage endplates	1939:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	11	82	theme	total	1514:1518	arg1	response					1520:1527	total response	1514:1527	total response	1514:1527	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	0	83	from	analysis	26:33	arg1	behaviors					69:77	the quasi-static biomechanical behaviors	38:77	the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	38:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	11	84	theme	degeneration	1551:1562	arg1	contribution					1471:1482	the long-term stress contribution	1450:1482	the long-term stress contribution	1450:1482	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	11	84	theme	degeneration	1551:1562	arg1	independent					1536:1546	independent	1536:1546	independent	1536:1546	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	1	85	theme	intervertebral	174:187	arg1	discs					189:193	intervertebral discs	174:193	intervertebral discs	174:193	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
37030175	2	86	from	effects	310:316	arg1	responses					368:376	the quasi-static biomechanical responses	337:376	the quasi-static biomechanical responses of discs	337:385	Up to the present, the effects of degeneration on the quasi-static biomechanical responses of discs have not been well understood.					
37030175	13	87	theme	models	1778:1783	arg1	constants					1751:1759	the engineering equilibrium time constants	1718:1759	the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability	1718:1836	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	0	88	theme	intervertebral	107:120	arg1	discs					122:126	healthy and degenerative intervertebral discs	82:126	healthy and degenerative intervertebral discs	82:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	7	89	theme	initial	1010:1016	arg1	modulus					1018:1024	the initial modulus	1006:1024	the initial modulus	1006:1024	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	16	90	theme	glycosaminoglycan	2203:2219	arg1	responsible					2232:2242	responsible	2232:2242	responsible	2232:2242	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	16	90	theme	glycosaminoglycan	2203:2219	arg1	content					2221:2227	the glycosaminoglycan content	2199:2227	the glycosaminoglycan content	2199:2227	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	6	91	theme	Voigt	766:770	arg1	models					791:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models	755:796	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	8	92	theme	cartilage	1108:1116	arg1	endplates					1118:1126	healthy cartilage endplates	1100:1126	healthy cartilage endplates	1100:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	17	93	theme	material	2402:2409	arg1	stiffness					2411:2419	material stiffness	2402:2419	material stiffness	2402:2419	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	17	94	theme	disc	2329:2332	arg1	degenerations					2334:2346	disc degenerations	2329:2346	disc degenerations	2329:2346	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	11	95	theme	long-term	1454:1462	arg1	contribution					1471:1482	the long-term stress contribution	1450:1482	the long-term stress contribution	1450:1482	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	11	95	theme	long-term	1454:1462	arg1	independent					1536:1546	independent	1536:1546	independent	1536:1546	In the stress-relaxation test, the long-term stress contribution occupies approximately 31% of total response and is independent of degeneration.					
37030175	0	96	theme	swelling-based	2:15	arg1	analysis					26:33	A swelling-based biphasic analysis	0:33	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	0:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	7	97	theme	nucleus	985:991	arg1	pulposus					993:1000	the nucleus pulposus	981:1000	the nucleus pulposus	981:1000	RESULTS Simulation results show that both the swelling-induced pressure in the nucleus pulposus and the initial modulus decrease with degeneration.					
37030175	17	98	theme	biomechanical	2538:2550	arg1	behaviors					2552:2560	the biomechanical behaviors	2534:2560	the biomechanical behaviors of degenerated discs	2534:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	10	99	theme	creep	1337:1341	arg1	test					1343:1346	the creep test	1333:1346	the creep test	1333:1346	For the creep test, over 50% of the deformation is contributed by the long-term response.					
37030175	9	100	with	discs	1269:1273	arg1	permeability					1292:1303	degenerated permeability	1280:1303	degenerated permeability in cartilage endplates	1280:1326	The long-term response is dominant for discs with degenerated permeability in cartilage endplates.					
37030175	8	101	contain	possessing	1089:1098	arg1	discs					1083:1087	discs	1083:1087	discs possessing healthy cartilage endplates	1083:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	8	101	contain	possessing	1089:1098	arg2	endplates					1118:1126	healthy cartilage endplates	1100:1126	healthy cartilage endplates	1100:1126	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	14	102	theme	glycosaminoglycan	1866:1882	arg1	content					1855:1861	The content	1851:1861	The content of glycosaminoglycan in intervertebral soft tissues	1851:1913	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	102	theme	glycosaminoglycan	1866:1882	arg1	CONCLUSIONS					1839:1849	CONCLUSIONS	1839:1849	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates	1839:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	14	102	theme	glycosaminoglycan	1866:1882	arg1	permeability					1923:1934	the permeability	1919:1934	the permeability of cartilage endplates	1919:1957	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	6	103	theme	tests	899:903	arg1	responses					880:888	the immediate (or residual), short-term and long-term responses	826:888	the immediate (or residual), short-term and long-term responses of these tests	826:903	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	4	104	theme	swelling-based	554:567	arg1	models					584:589	Four biphasic swelling-based finite element models	540:589	METHODS Four biphasic swelling-based finite element models	532:589	METHODS Four biphasic swelling-based finite element models are developed and quantitatively validated.					
37030175	13	105	theme	equilibrium	1734:1744	arg1	constants					1751:1759	the engineering equilibrium time constants	1718:1759	the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability	1718:1836	In addition, both the glycosaminoglycan content and permeability affect the engineering equilibrium time constants of the rheologic models, in which the determining factor is the permeability.					
37030175	0	106	theme	biomechanical	55:67	arg1	behaviors					69:77	the quasi-static biomechanical behaviors	38:77	the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs	38:126	A swelling-based biphasic analysis on the quasi-static biomechanical behaviors of healthy and degenerative intervertebral discs.					
37030175	4	107	dep	METHODS	532:538	arg1	models					584:589	Four biphasic swelling-based finite element models	540:589	METHODS Four biphasic swelling-based finite element models	532:589	METHODS Four biphasic swelling-based finite element models are developed and quantitatively validated.					
37030175	17	108	dep	composition	2482:2492	arg1	permeability					2518:2529	permeability	2518:2529	permeability	2518:2529	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	4	109	theme	element	576:582	arg1	models					584:589	Four biphasic swelling-based finite element models	540:589	METHODS Four biphasic swelling-based finite element models	532:589	METHODS Four biphasic swelling-based finite element models are developed and quantitatively validated.					
37030175	15	110	theme	viscoelastic	2113:2124	arg1	responses					2126:2134	the fluid-dependent viscoelastic responses	2093:2134	the fluid-dependent viscoelastic responses	2093:2134	The component proportions of the fluid-dependent viscoelastic responses depend also strongly on test protocols.					
37030175	3	111	theme	degenerative	512:523	arg1	discs					525:529	healthy and degenerative discs	500:529	healthy and degenerative discs	500:529	The goal of this study is to quantitatively analyze the quasi-static responses of healthy and degenerative discs.					
37030175	6	112	theme	long-term	870:878	arg1	responses					880:888	the immediate (or residual), short-term and long-term responses	826:888	the immediate (or residual), short-term and long-term responses of these tests	826:903	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	14	113	theme	discs	2057:2061	arg1	responses					2029:2037	the fluid-dependent viscoelastic responses	1996:2037	the fluid-dependent viscoelastic responses of intervertebral discs	1996:2061	CONCLUSIONS The content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs.					
37030175	17	114	theme	discs	2577:2581	arg1	behaviors					2552:2560	the biomechanical behaviors	2534:2560	the biomechanical behaviors of degenerated discs	2534:2581	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	17	115	theme	biochemical	2470:2480	arg1	composition					2482:2492	biochemical composition	2470:2492	biochemical composition	2470:2492	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	16	116	theme	slow-ramp	2183:2191	arg1	test					2193:2196	the slow-ramp test	2179:2196	the slow-ramp test	2179:2196	In the slow-ramp test, the glycosaminoglycan content is responsible for the changes of the initial modulus.					
37030175	12	117	dep	responses	1598:1606	arg1	Both					1565:1568	Both	1565:1568	Both	1565:1568	Both the residual and short-term responses vary monotonically with degeneration.					
37030175	10	118	theme	long-term	1399:1407	arg1	response					1409:1416	the long-term response	1395:1416	the long-term response	1395:1416	For the creep test, over 50% of the deformation is contributed by the long-term response.					
37030175	3	119	theme	healthy	500:506	arg1	discs					525:529	healthy and degenerative discs	500:529	healthy and degenerative discs	500:529	The goal of this study is to quantitatively analyze the quasi-static responses of healthy and degenerative discs.					
37030175	8	120	theme	total	1174:1178	arg1	strain					1180:1185	the total strain	1170:1185	the total strain	1170:1185	In the free-swelling test of discs possessing healthy cartilage endplates, simulation results show that over 80% of the total strain is contributed by the short-term response.					
37030175	6	121	theme	short-term	855:864	arg1	responses					880:888	the immediate (or residual), short-term and long-term responses	826:888	the immediate (or residual), short-term and long-term responses of these tests	826:903	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	17	122	theme	existing	2290:2297	arg1	models					2313:2318	existing computational models	2290:2318	existing computational models	2290:2318	Since existing computational models simulate disc degenerations only by altering disc height, boundary conditions and material stiffness, the current work highlights the significance of biochemical composition and cartilage endplates permeability in the biomechanical behaviors of degenerated discs.					
37030175	6	123	theme	double	776:781	arg1	Maxwell					783:789	double Maxwell	776:789	double Maxwell	776:789	The double Voigt and double Maxwell models are further used to extract the immediate (or residual), short-term and long-term responses of these tests.					
37030175	1	124	theme	tissue	269:274	arg1	structure					276:284	tissue structure	269:284	tissue structure	269:284	BACKGROUND AND OBJECTIVE The degeneration of intervertebral discs is significantly dependent of the changes in tissue composition ratio and tissue structure.					
35703732	7	0	theme	esophageal	1239:1248	arg1	scaffolds					1250:1258	piglet esophageal scaffolds	1232:1258	piglet esophageal scaffolds	1232:1258	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	0	1	with	modification	86:97	arg1	gel					113:115	EETs-ECM gel	104:115	EETs-ECM gel	104:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	3	2	theme	homologous	480:489	arg1	ECM					513:515	ECM	513:515	ECM	513:515	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	3	2	theme	homologous	480:489	arg1	matrix					505:510	extracellular matrix	491:510	the processed homologous extracellular matrix (ECM)	466:516	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	1	3	theme	biological	239:248	arg1	response					250:257	their biological response	233:257	their biological response	233:257	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	6	4	theme	ECM	910:912	arg1	gel					914:916	ECM gel	910:916	ECM gel containing epoxyeicosatrienoic acids (EETs)	910:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	10	5	theme	full-thickness	1631:1644	arg1	replacement					1664:1674	rabbit full-thickness esophageal defect replacement	1624:1674	rabbit full-thickness esophageal defect replacement	1624:1674	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	7	6	theme	better	1109:1114	arg1	efficiency					1116:1125	a better efficiency	1107:1125	a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin	1107:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	4	7	from	piglets	627:633	arg1	decellularization					547:563	the decellularization	543:563	the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion	543:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	9	8	theme	esophageal	1445:1454	arg1	cells					1467:1471	esophageal epithelial cells	1445:1471	esophageal epithelial cells	1445:1471	Coating of bioscaffolds with ECM gel is suitable for carrying esophageal epithelial cells and EETs.					
35703732	4	9	theme	45-days	615:621	arg1	piglets					627:633	45-days old piglets	615:633	45-days old piglets	615:633	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	6	10	theme	derived	875:881	arg1	bioscaffolds					883:894	esophageal submucosal derived bioscaffolds	853:894	esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs)	853:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	7	11	theme	higher	1176:1181	arg1	retention					1183:1191	a higher retention	1174:1191	a higher retention of sGAG and fibronectin	1174:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	6	12	contain	containing	918:927	arg1	gel					914:916	ECM gel	910:916	ECM gel containing epoxyeicosatrienoic acids (EETs)	910:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	6	12	contain	containing	918:927	arg2	EETs					956:959	EETs	956:959	EETs	956:959	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	6	12	contain	containing	918:927	arg2	acids					949:953	epoxyeicosatrienoic acids	929:953	epoxyeicosatrienoic acids (EETs)	929:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	7	13	theme	donor	1096:1100	arg1	age					1102:1104	the donor age	1092:1104	the donor age	1092:1104	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	4	14	from	21-	607:609	arg1	decellularization					547:563	the decellularization	543:563	the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion	543:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	10	15	theme	defect	1657:1662	arg1	replacement					1664:1674	rabbit full-thickness esophageal defect replacement	1624:1674	rabbit full-thickness esophageal defect replacement	1624:1674	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	2	16	theme	study	283:287	arg1	case					275:278	An interesting case	260:278	An interesting case of study it	260:290	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	2	16	theme	study	283:287	arg1	esophagus					307:315	the porcine esophagus	295:315	the porcine esophagus	295:315	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	4	17	from	1-	603:604	arg1	decellularization					547:563	the decellularization	543:563	the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion	543:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	4	18	theme	reversible	662:671	arg1	swelling					682:689	reversible alkaline swelling	662:689	reversible alkaline swelling	662:689	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	8	19	theme	esophageal	1287:1296	arg1	ECM					1298:1300	this esophageal ECM	1282:1300	this esophageal ECM	1282:1300	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	5	20	theme	tensile	795:801	arg1	properties					814:823	tensile mechanical properties	795:823	tensile mechanical properties	795:823	The bioscaffolds were characterized in terms of their residual composition and tensile mechanical properties.					
35703732	1	21	theme	primary	208:214	arg1	goals					216:220	the primary goals	204:220	the primary goals	204:220	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	4	22	theme	alkaline	673:680	arg1	swelling					682:689	reversible alkaline swelling	662:689	reversible alkaline swelling	662:689	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	7	23	theme	sulphated	1046:1054	arg1	glycosaminoglycans/sGAG					1056:1078	sulphated glycosaminoglycans/sGAG	1046:1078	sulphated glycosaminoglycans/sGAG	1046:1078	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	8	24	gly	heterogeneity	1265:1277	arg1	ECM					1298:1300	this esophageal ECM	1282:1300	this esophageal ECM	1282:1300	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	1	25	theme	complex	126:132	arg1	organs					142:147	Damaged complex modular organs	118:147	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	1	26	theme	organs	142:147	arg1	challenge					178:186	a current clinical challenge	159:186	a current clinical challenge in which one of the primary goals is to keep their biological response	159:257	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	1	26	theme	organs	142:147	arg1	repair					149:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	7	27	theme	piglet	1232:1237	arg1	scaffolds					1250:1258	piglet esophageal scaffolds	1232:1258	piglet esophageal scaffolds	1232:1258	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	5	28	theme	mechanical	803:812	arg1	properties					814:823	tensile mechanical properties	795:823	tensile mechanical properties	795:823	The bioscaffolds were characterized in terms of their residual composition and tensile mechanical properties.					
35703732	0	29	theme	bioscaffold	74:84	arg1	modification					86:97	the bioscaffold modification	70:97	the bioscaffold modification with EETs-ECM gel	70:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	1	30	theme	current	161:167	arg1	challenge					178:186	a current clinical challenge	159:186	a current clinical challenge in which one of the primary goals is to keep their biological response	159:257	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	1	30	theme	current	161:167	arg1	repair					149:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	8	31	theme	anisotropic	1351:1361	arg1	properties					1371:1380	anisotropic tensile properties	1351:1380	anisotropic tensile properties	1351:1380	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	7	32	theme	fibronectin	1205:1215	arg1	retention					1183:1191	a higher retention	1174:1191	a higher retention of sGAG and fibronectin	1174:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	10	33	theme	EETs-ECM	1498:1505	arg1	bioscaffolds					1542:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	2	34	theme	tissue	384:389	arg1	engineering					391:401	tissue engineering	384:401	tissue engineering	384:401	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	8	35	theme	properties	1371:1380	arg1	preservation					1335:1346	the preservation	1331:1346	the preservation of anisotropic tensile properties	1331:1380	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	2	36	theme	raw	367:369	arg1	material					371:378	raw material	367:378	raw material for tissue engineering	367:401	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	7	37	theme	sGAG	1196:1199	arg1	retention					1183:1191	a higher retention	1174:1191	a higher retention of sGAG and fibronectin	1174:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	4	38	theme	perfusion	705:713	arg1	combination					647:657	the combination	643:657	the combination of reversible alkaline swelling and detergent perfusion	643:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	10	39	theme	submucosal	1531:1540	arg1	bioscaffolds					1542:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	0	40	theme	porcine	21:27	arg1	tissue					40:45	porcine esophageal tissue	21:45	porcine esophageal tissue	21:45	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	6	41	theme	submucosal	864:873	arg1	bioscaffolds					883:894	esophageal submucosal derived bioscaffolds	853:894	esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs)	853:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	10	42	theme	modified	1511:1518	arg1	bioscaffolds					1542:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	3	43	theme	esophageal	418:427	arg1	constructs					429:438	esophageal constructs	418:438	esophageal constructs	418:438	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	9	44	theme	epithelial	1456:1465	arg1	cells					1467:1471	esophageal epithelial cells	1445:1471	esophageal epithelial cells	1445:1471	Coating of bioscaffolds with ECM gel is suitable for carrying esophageal epithelial cells and EETs.					
35703732	0	45	theme	tissue	40:45	arg1	Decellularization					0:16	Decellularization	0:16	Decellularization of porcine esophageal tissue at three diameters	0:64	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	0	45	theme	tissue	40:45	arg1	modification					86:97	the bioscaffold modification	70:97	the bioscaffold modification with EETs-ECM gel	70:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	7	46	theme	decellularization	1134:1150	arg1	process					1152:1158	the decellularization process	1130:1158	the decellularization process combined with a higher retention of sGAG and fibronectin	1130:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	6	47	theme	biological	830:839	arg1	response					841:848	The biological response	826:848	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs)	826:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	0	48	with	Decellularization	0:16	arg1	gel					113:115	EETs-ECM gel	104:115	EETs-ECM gel	104:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	1	49	theme	goals	216:220	arg1	goals					216:220	the primary goals	204:220	the primary goals	204:220	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	1	49	theme	goals	216:220	arg1	one					197:199	one	197:199	one	197:199	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	3	50	theme	extracellular	491:503	arg1	ECM					513:515	ECM	513:515	ECM	513:515	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	3	50	theme	extracellular	491:503	arg1	matrix					505:510	extracellular matrix	491:510	the processed homologous extracellular matrix (ECM)	466:516	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	6	51	theme	epoxyeicosatrienoic	929:947	arg1	EETs					956:959	EETs	956:959	EETs	956:959	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	6	51	theme	epoxyeicosatrienoic	929:947	arg1	acids					949:953	epoxyeicosatrienoic acids	929:953	epoxyeicosatrienoic acids (EETs)	929:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	4	52	theme	esophagus	581:589	arg1	tissue					591:596	multilayered esophagus tissue	568:596	multilayered esophagus tissue	568:596	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	3	53	theme	processed	470:478	arg1	ECM					513:515	ECM	513:515	ECM	513:515	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	3	53	theme	processed	470:478	arg1	matrix					505:510	extracellular matrix	491:510	the processed homologous extracellular matrix (ECM)	466:516	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	10	54	theme	esophageal	1646:1655	arg1	replacement					1664:1674	rabbit full-thickness esophageal defect replacement	1624:1674	rabbit full-thickness esophageal defect replacement	1624:1674	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	8	55	theme	ECM	1298:1300	arg1	heterogeneity					1265:1277	The heterogeneity	1261:1277	The heterogeneity of this esophageal ECM	1261:1300	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	10	56	theme	rabbit	1624:1629	arg1	replacement					1664:1674	rabbit full-thickness esophageal defect replacement	1624:1674	rabbit full-thickness esophageal defect replacement	1624:1674	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	9	57	with	Coating	1383:1389	arg1	gel					1416:1418	ECM gel	1412:1418	ECM gel	1412:1418	Coating of bioscaffolds with ECM gel is suitable for carrying esophageal epithelial cells and EETs.					
35703732	2	58	theme	interesting	263:273	arg1	case					275:278	An interesting case	260:278	An interesting case of study it	260:290	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	2	58	theme	interesting	263:273	arg1	esophagus					307:315	the porcine esophagus	295:315	the porcine esophagus	295:315	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	1	59	theme	clinical	169:176	arg1	challenge					178:186	a current clinical challenge	159:186	a current clinical challenge in which one of the primary goals is to keep their biological response	159:257	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	1	59	theme	clinical	169:176	arg1	repair					149:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	5	60	theme	residual	770:777	arg1	composition					779:789	their residual composition	764:789	their residual composition	764:789	The bioscaffolds were characterized in terms of their residual composition and tensile mechanical properties.					
35703732	4	61	theme	old	623:625	arg1	piglets					627:633	45-days old piglets	615:633	45-days old piglets	615:633	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	5	62	theme	properties	814:823	arg1	terms					755:759	terms	755:759	terms of their residual composition and tensile mechanical properties	755:823	The bioscaffolds were characterized in terms of their residual composition and tensile mechanical properties.					
35703732	2	63	theme	muscular	339:346	arg1	tissue					348:353	a tubular muscular tissue	329:353	a tubular muscular tissue selected as raw material for tissue engineering	329:401	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	2	63	theme	muscular	339:346	arg1	it					323:324	it	323:324	it	323:324	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	1	64	theme	Damaged	118:124	arg1	organs					142:147	Damaged complex modular organs	118:147	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	2	65	dep	study	283:287	arg1	it					289:290	it	289:290	it	289:290	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	1	66	theme	modular	134:140	arg1	organs					142:147	Damaged complex modular organs	118:147	Damaged complex modular organs repair	118:154	Damaged complex modular organs repair is a current clinical challenge in which one of the primary goals is to keep their biological response.					
35703732	4	67	theme	swelling	682:689	arg1	combination					647:657	the combination	643:657	the combination of reversible alkaline swelling and detergent perfusion	643:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	0	68	theme	EETs-ECM	104:111	arg1	gel					113:115	EETs-ECM gel	104:115	EETs-ECM gel	104:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	0	69	from	diameters	56:64	arg1	Decellularization					0:16	Decellularization	0:16	Decellularization of porcine esophageal tissue at three diameters	0:64	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	0	69	from	diameters	56:64	arg1	modification					86:97	the bioscaffold modification	70:97	the bioscaffold modification with EETs-ECM gel	70:115	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	7	70	dep	composition	1007:1017	arg1	fibronectin					1029:1039	fibronectin	1029:1039	fibronectin	1029:1039	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	7	70	dep	composition	1007:1017	arg1	laminin					1020:1026	laminin	1020:1026	laminin	1020:1026	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	7	70	dep	composition	1007:1017	arg1	glycosaminoglycans/sGAG					1056:1078	sulphated glycosaminoglycans/sGAG	1046:1078	sulphated glycosaminoglycans/sGAG	1046:1078	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	8	71	theme	tensile	1363:1369	arg1	properties					1371:1380	anisotropic tensile properties	1351:1380	anisotropic tensile properties	1351:1380	The heterogeneity of this esophageal ECM is maintained, which implied the preservation of anisotropic tensile properties.					
35703732	5	72	theme	composition	779:789	arg1	terms					755:759	terms	755:759	terms of their residual composition and tensile mechanical properties	755:823	The bioscaffolds were characterized in terms of their residual composition and tensile mechanical properties.					
35703732	4	73	theme	detergent	695:703	arg1	perfusion					705:713	detergent perfusion	695:713	detergent perfusion	695:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	0	74	theme	esophageal	29:38	arg1	tissue					40:45	porcine esophageal tissue	21:45	porcine esophageal tissue	21:45	Decellularization of porcine esophageal tissue at three diameters and the bioscaffold modification with EETs-ECM gel.					
35703732	10	75	theme	esophageal	1520:1529	arg1	bioscaffolds					1542:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	6	76	link	derived	875:881	arg1	bioscaffolds					883:894	esophageal submucosal derived bioscaffolds	853:894	esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs)	853:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	7	77	theme	process	1152:1158	arg1	efficiency					1116:1125	a better efficiency	1107:1125	a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin	1107:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	6	78	theme	esophageal	853:862	arg1	bioscaffolds					883:894	esophageal submucosal derived bioscaffolds	853:894	esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs)	853:960	The biological response to esophageal submucosal derived bioscaffolds modified with ECM gel containing epoxyeicosatrienoic acids (EETs) was then evaluated.					
35703732	10	79	theme	gel	1507:1509	arg1	bioscaffolds					1542:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	EETs-ECM gel modified esophageal submucosal bioscaffolds	1498:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	3	80	theme	constructs	429:438	arg1	design					408:413	The design	404:413	The design of esophageal constructs	404:438	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
35703732	2	81	theme	tubular	331:337	arg1	tissue					348:353	a tubular muscular tissue	329:353	a tubular muscular tissue selected as raw material for tissue engineering	329:401	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	2	81	theme	tubular	331:337	arg1	it					323:324	it	323:324	it	323:324	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	9	82	theme	bioscaffolds	1394:1405	arg1	Coating					1383:1389	Coating	1383:1389	Coating of bioscaffolds with ECM gel	1383:1418	Coating of bioscaffolds with ECM gel is suitable for carrying esophageal epithelial cells and EETs.					
35703732	4	83	theme	multilayered	568:579	arg1	tissue					591:596	multilayered esophagus tissue	568:596	multilayered esophagus tissue	568:596	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	10	84	theme	bioscaffolds	1542:1553	arg1	Bioactivity					1483:1493	Bioactivity	1483:1493	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds	1483:1553	Bioactivity of EETs-ECM gel modified esophageal submucosal bioscaffolds is observed to promote neovascularization and antiinflammatory after rabbit full-thickness esophageal defect replacement.					
35703732	2	85	theme	porcine	299:305	arg1	case					275:278	An interesting case	260:278	An interesting case of study it	260:290	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	2	85	theme	porcine	299:305	arg1	esophagus					307:315	the porcine esophagus	295:315	the porcine esophagus	295:315	An interesting case of study it is the porcine esophagus since it is a tubular muscular tissue selected as raw material for tissue engineering.					
35703732	9	86	theme	ECM	1412:1414	arg1	gel					1416:1418	ECM gel	1412:1418	ECM gel	1412:1418	Coating of bioscaffolds with ECM gel is suitable for carrying esophageal epithelial cells and EETs.					
35703732	4	87	theme	tissue	591:596	arg1	decellularization					547:563	the decellularization	543:563	the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion	543:713	In this work, we report the decellularization of multilayered esophagus tissue from 1-, 21- and 45-days old piglets through the combination of reversible alkaline swelling and detergent perfusion.					
35703732	7	88	located	observed	1220:1227	arg2	efficiency					1116:1125	a better efficiency	1107:1125	a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin	1107:1215	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	7	88	located	observed	1220:1227	arg1	scaffolds					1250:1258	piglet esophageal scaffolds	1232:1258	piglet esophageal scaffolds	1232:1258	Results suggest that the composition (laminin, fibronectin, and sulphated glycosaminoglycans/sGAG) depends on the donor age: a better efficiency of the decellularization process combined with a higher retention of sGAG and fibronectin is observed in piglet esophageal scaffolds.					
35703732	3	89	theme	matrix	505:510	arg1	properties					452:461	properties	452:461	properties of the processed homologous extracellular matrix (ECM)	452:516	The design of esophageal constructs can draw on properties of the processed homologous extracellular matrix (ECM).					
37330062	1	0	theme	biomass	322:328	arg1	particle					330:337	a biomass particle	320:337	a biomass particle in pyrolysis	320:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	1	from	surface	309:315	arg1	pyrolysis					342:350	pyrolysis	342:350	pyrolysis	342:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	3	2	theme	lignin-	471:477	arg1	volatiles					501:509	lignin- and cellulose-derived volatiles	471:509	lignin- and cellulose-derived volatiles	471:509	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	1	3	theme	particle	330:337	arg1	surface					309:315	outer surface	303:315	outer surface of a biomass particle in pyrolysis	303:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	0	4	link	lignin-/cellulose-derived	19:43	arg1	char					45:48	the lignin-/cellulose-derived char	15:48	the lignin-/cellulose-derived char	15:48	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	6	5	theme	organics	1084:1091	arg1	gasification					1063:1074	gasification	1063:1074	gasification of some organics	1063:1091	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	7	6	theme	deposit	1325:1331	arg1	formation					1305:1313	formation	1305:1313	formation of carbon deposit	1305:1331	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	7	6	theme	deposit	1325:1331	arg1	exchange					1292:1299	the substance exchange	1278:1299	the substance exchange	1278:1299	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	7	7	theme	fragmented	1363:1372	arg1	surface					1374:1380	fragmented surface	1363:1380	fragmented surface dotted with particulate matters in the used char catalysts	1363:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	4	8	theme	phenolics	675:683	arg1	polymerization					638:651	polymerization	638:651	polymerization of the lignin-derived phenolics	638:683	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	5	9	theme	more	956:959	arg1	gases					961:965	more gases	956:965	more gases	956:965	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	6	10	theme	enhanced	1166:1173	arg1	crystallinity					1175:1187	crystallinity	1175:1187	crystallinity	1175:1187	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	3	11	link	cellulose-derived	483:499	arg1	volatiles					501:509	lignin- and cellulose-derived volatiles	471:509	lignin- and cellulose-derived volatiles	471:509	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	3	12	theme	varied	524:529	arg1	origin					531:536	varied origin	524:536	varied origin	524:536	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	0	13	from	pyrolysis	132:140	arg1	evolution					107:115	evolution	107:115	evolution of products in pyrolysis	107:140	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	7	14	with	dotted	1382:1387	arg1	matters					1406:1412	particulate matters	1394:1412	particulate matters in the used char catalysts	1394:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	4	15	dep	%	731:731	arg1	ca.					721:723	ca. 20%-30%	721:731	ca. 20%-30%	721:731	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	4	16	theme	heavy	750:754	arg1	tar					756:758	more heavy tar	745:758	more heavy tar	745:758	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	2	17	theme	volatiles	385:393	arg1	property					409:416	property	409:416	property of char	409:424	This shapes both composition of volatiles (bio-oil) and property of char.					
37330062	2	17	theme	volatiles	385:393	arg1	composition					370:380	composition	370:380	composition of volatiles (bio-oil)	370:403	This shapes both composition of volatiles (bio-oil) and property of char.					
37330062	0	18	theme	process	95:101	arg1	Part					83:86	Part	83:86	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.	0:141	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	1	19	from	core	295:298	arg1	volatiles					274:282	volatiles	274:282	volatiles from inner core	274:298	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	19	from	core	295:298	arg1	diffusion					261:269	diffusion	261:269	diffusion	261:269	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	19	from	core	295:298	arg1	transfer					249:256	transfer	249:256	transfer	249:256	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	5	20	theme	heterologous	872:883	arg1	lignin-char					885:895	the heterologous lignin-char	868:895	especially the heterologous lignin-char	857:895	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	5	20	theme	heterologous	872:883	arg1	catalysts					846:854	the char catalysts	837:854	the char catalysts	837:854	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	5	21	theme	char	841:844	arg1	lignin-char					885:895	the heterologous lignin-char	868:895	especially the heterologous lignin-char	857:895	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	5	21	theme	char	841:844	arg1	catalysts					846:854	the char catalysts	837:854	the char catalysts	837:854	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	7	22	theme	dotted	1382:1387	arg1	surface					1374:1380	fragmented surface	1363:1380	fragmented surface dotted with particulate matters in the used char catalysts	1363:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	3	23	with	interaction	456:466	arg1	char					516:519	char	516:519	char of varied origin	516:536	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	6	24	theme	catalyst	1226:1233	arg1	thermostability					1193:1207	thermostability	1193:1207	thermostability	1193:1207	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	6	24	theme	catalyst	1226:1233	arg1	crystallinity					1175:1187	crystallinity	1175:1187	crystallinity	1175:1187	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	4	25	theme	lignin-derived	660:673	arg1	phenolics					675:683	the lignin-derived phenolics	656:683	the lignin-derived phenolics	656:683	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	2	26	theme	char	421:424	arg1	property					409:416	property	409:416	property of char	409:424	This shapes both composition of volatiles (bio-oil) and property of char.					
37330062	2	26	theme	char	421:424	arg1	composition					370:380	composition	370:380	composition of volatiles (bio-oil)	370:403	This shapes both composition of volatiles (bio-oil) and property of char.					
37330062	1	27	theme	volatiles	274:282	arg1	diffusion					261:269	diffusion	261:269	diffusion	261:269	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	27	theme	volatiles	274:282	arg1	transfer					249:256	transfer	249:256	transfer	249:256	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	4	28	theme	20	725:726	arg1	%					727:727	%	727:727	%	727:727	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	1	29	theme	homologous	181:190	arg1	char					212:215	homologous and/or heterologous char	181:215	homologous and/or heterologous char	181:215	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	30	from	pyrolysis	342:350	arg1	surface					309:315	outer surface	303:315	outer surface of a biomass particle in pyrolysis	303:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	5	31	theme	heavy	990:994	arg1	organics					996:1003	less bio-oil and heavy organics	973:1003	less bio-oil and heavy organics	973:1003	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	1	32	from	diffusion	261:269	arg1	core					295:298	inner core	289:298	inner core	289:298	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	3	33	theme	origin	531:536	arg1	char					516:519	char	516:519	char of varied origin	516:536	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	4	34	dep	promoted	629:636	arg1	enhancing					686:694	enhancing	686:694	enhancing production of bio-oil by ca. 20%-30%	686:731	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	4	34	dep	promoted	629:636	arg1	suppressing					764:774	suppressing	764:774	suppressing gases formation	764:790	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	4	34	dep	promoted	629:636	arg1	generating					734:743	generating	734:743	generating more heavy tar	734:758	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	6	35	theme	char	1147:1150	arg1	surface					1136:1142	surface	1136:1142	surface of char	1136:1150	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	1	36	theme	inner	289:293	arg1	core					295:298	inner core	289:298	inner core	289:298	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	7	37	theme	used	1421:1424	arg1	catalysts					1431:1439	the used char catalysts	1417:1439	the used char catalysts	1417:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	4	38	theme	-30	728:730	arg1	%					727:727	%	727:727	%	727:727	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	1	39	theme	heterologous	199:210	arg1	char					212:215	homologous and/or heterologous char	181:215	homologous and/or heterologous char	181:215	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	40	from	particle	330:337	arg1	pyrolysis					342:350	pyrolysis	342:350	pyrolysis	342:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	1	41	from	transfer	249:256	arg1	core					295:298	inner core	289:298	inner core	289:298	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	4	42	link	lignin-derived	660:673	arg1	phenolics					675:683	the lignin-derived phenolics	656:683	the lignin-derived phenolics	656:683	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	7	43	theme	carbon	1318:1323	arg1	deposit					1325:1331	carbon deposit	1318:1331	carbon deposit	1318:1331	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	7	44	theme	substance	1282:1290	arg1	exchange					1292:1299	the substance exchange	1278:1299	the substance exchange	1278:1299	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	0	45	theme	char	45:48	arg1	Interaction					0:10	Interaction	0:10	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.	0:141	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	0	46	theme	products	120:127	arg1	evolution					107:115	evolution	107:115	evolution of products in pyrolysis	107:140	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	0	47	theme	lignin-/cellulose-derived	19:43	arg1	char					45:48	the lignin-/cellulose-derived char	15:48	the lignin-/cellulose-derived char	15:48	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	6	48	theme	volatiles-char	1024:1037	arg1	interaction					1039:1049	the volatiles-char interaction	1020:1049	the volatiles-char interaction	1020:1049	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	1	49	theme	outer	303:307	arg1	surface					309:315	outer surface	303:315	outer surface of a biomass particle in pyrolysis	303:350	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	6	50	theme	char	1221:1224	arg1	catalyst					1226:1233	the used char catalyst	1212:1233	the used char catalyst	1212:1233	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	4	51	theme	bio-oil	710:716	arg1	production					696:705	production	696:705	production of bio-oil	696:716	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	6	52	theme	used	1216:1219	arg1	catalyst					1226:1233	the used char catalyst	1212:1233	the used char catalyst	1212:1233	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	6	53	theme	organics	1124:1131	arg1	aromatization					1102:1114	aromatization	1102:1114	aromatization of some organics	1102:1131	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	5	54	theme	bio-oil	978:984	arg1	organics					996:1003	less bio-oil and heavy organics	973:1003	less bio-oil and heavy organics	973:1003	Conversely, the char catalysts, especially the heterologous lignin-char, promoted cracking of the cellulose-derivatives, producing more gases while less bio-oil and heavy organics.					
37330062	0	55	with	Interaction	0:10	arg1	volatiles					55:63	volatiles	55:63	volatiles of varied origin	55:80	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	7	56	theme	particulate	1394:1404	arg1	matters					1406:1412	particulate matters	1394:1412	particulate matters in the used char catalysts	1394:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	7	57	theme	char	1426:1429	arg1	catalysts					1431:1439	the used char catalysts	1417:1439	the used char catalysts	1417:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	1	58	dep	transfer	249:256	arg1	the					245:247	the	245:247	the	245:247	The interaction between volatiles and homologous and/or heterologous char is almost inevitable during the transfer or diffusion of volatiles from inner core to outer surface of a biomass particle in pyrolysis.					
37330062	3	59	theme	potential	446:454	arg1	interaction					456:466	the potential interaction	442:466	the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin	442:536	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	0	60	from	products	120:127	arg1	pyrolysis					132:140	pyrolysis	132:140	pyrolysis	132:140	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	0	61	theme	origin	75:80	arg1	volatiles					55:63	volatiles	55:63	volatiles of varied origin	55:80	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	4	62	theme	gases	776:780	arg1	formation					782:790	gases formation	776:790	gases formation	776:790	The results indicated that both the lignin- and cellulose-char promoted polymerization of the lignin-derived phenolics, enhancing production of bio-oil by ca. 20%-30%, generating more heavy tar but suppressing gases formation, especially over cellulose-char.					
37330062	3	63	theme	cellulose-derived	483:499	arg1	volatiles					501:509	lignin- and cellulose-derived volatiles	471:509	lignin- and cellulose-derived volatiles	471:509	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	7	64	from	matters	1406:1412	arg1	catalysts					1431:1439	the used char catalysts	1417:1439	the used char catalysts	1417:1439	Moreover, the substance exchange and formation of carbon deposit also blocked pores and formed fragmented surface dotted with particulate matters in the used char catalysts.					
37330062	0	65	theme	varied	68:73	arg1	origin					75:80	varied origin	68:80	varied origin	68:80	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	0	66	dep	Interaction	0:10	arg1	Part					83:86	Part	83:86	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.	0:141	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
37330062	6	67	from	aromatization	1102:1114	arg1	surface					1136:1142	surface	1136:1142	surface of char	1136:1150	Additionally, the volatiles-char interaction also led to gasification of some organics and also aromatization of some organics on surface of char, resulting in enhanced crystallinity and thermostability of the used char catalyst, especially for the lignin-char.					
37330062	3	68	theme	volatiles	501:509	arg1	interaction					456:466	the potential interaction	442:466	the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin	442:536	In this study, the potential interaction of lignin- and cellulose-derived volatiles with char of varied origin was investigated at 500 °C.					
37330062	0	69	from	evolution	107:115	arg1	pyrolysis					132:140	pyrolysis	132:140	pyrolysis	132:140	Interaction of the lignin-/cellulose-derived char with volatiles of varied origin: Part of the process for evolution of products in pyrolysis.					
36197539	4	0	theme	juvenile	727:734	arg1	74.9 ± 4.4 g					750:761	Wt0 74.9 ± 4.4 g	746:761	Wt0 74.9 ± 4.4 g	746:761	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	0	theme	juvenile	727:734	arg1	drum					740:743	38 juvenile red drum	724:743	38 juvenile red drum (Wt0 74.9 ± 4.4 g)	724:762	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	3	1	theme	striped	435:441	arg1	HSB					449:451	HSB	449:451	HSB	449:451	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	3	1	theme	striped	435:441	arg1	bass					443:446	hybrid striped bass	428:446	hybrid striped bass (HSB)	428:452	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	11	2	from	study	1580:1584	arg1	Results					1562:1568	Results	1562:1568	Results from this study	1562:1584	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	7	3	theme	control	1249:1255	arg1	treatments					1258:1267	RD vs static (control) treatments	1235:1267	treatments	1258:1267	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	7	4	theme	exercised	1213:1221	arg1	tilapia					1223:1229	exercised tilapia	1213:1229	exercised tilapia	1213:1229	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	7	5	theme	static	1241:1246	arg1	treatments					1258:1267	RD vs static (control) treatments	1235:1267	treatments	1258:1267	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	0	6	theme	striped	164:170	arg1	bass					172:175	hybrid striped bass	157:175	hybrid striped bass (Morone chrysops × M. saxatilis)	157:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	6	theme	striped	164:170	arg1	saxatilis					199:207	Morone chrysops × M. saxatilis	178:207	Morone chrysops × M. saxatilis	178:207	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	7	7	theme	RD	1235:1236	arg1	treatments					1258:1267	RD vs static (control) treatments	1235:1267	treatments	1258:1267	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	7	8	theme	gain	1190:1193	arg1	enhancements					1167:1178	Significant (P ≤ 0.05) enhancements	1144:1178	Significant (P ≤ 0.05) enhancements of weight gain	1144:1193	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	3	9	from	swim	594:597	arg1	system					619:624	a static culture system	602:624	a static culture system	602:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	3	10	theme	static	604:609	arg1	system					619:624	a static culture system	602:624	a static culture system	602:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	10	11	located	detected	1506:1513	arg1	glycogen					1524:1531	liver glycogen	1518:1531	liver glycogen of exercised tilapia and RD	1518:1559	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	10	11	located	detected	1506:1513	arg2	reductions					1485:1494	Significant reductions	1473:1494	Significant reductions	1473:1494	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	10	12	theme	exercised	1536:1544	arg1	tilapia					1546:1552	exercised tilapia	1536:1552	exercised tilapia	1536:1552	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	4	13	theme	juvenile	772:779	arg1	HSB					781:783	20 juvenile HSB	769:783	20 juvenile HSB (Wt0 78.0 ± 3.2 g)	769:802	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	13	theme	juvenile	772:779	arg1	78.0 ± 3.2 g					790:801	Wt0 78.0 ± 3.2 g	786:801	Wt0 78.0 ± 3.2 g	786:801	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	11	14	theme	growth	1674:1679	arg1	aspects					1642:1648	aspects	1642:1648	aspects of tilapia and red drum growth	1642:1679	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	4	15	theme	Wt0	746:748	arg1	74.9 ± 4.4 g					750:761	Wt0 74.9 ± 4.4 g	746:761	Wt0 74.9 ± 4.4 g	746:761	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	15	theme	Wt0	746:748	arg1	drum					740:743	38 juvenile red drum	724:743	38 juvenile red drum (Wt0 74.9 ± 4.4 g)	724:762	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	0	16	theme	drum	125:128	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	17	theme	Sciaenops	131:139	arg1	drum					125:128	red drum	121:128	red drum (Sciaenops ocellatus)	121:150	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	17	theme	Sciaenops	131:139	arg1	ocellatus					141:149	Sciaenops ocellatus	131:149	Sciaenops ocellatus	131:149	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	18	theme	body	53:56	arg1	composition					58:68	body composition	53:68	body composition	53:68	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	3	19	theme	slow	506:509	arg1	current					511:517	a constant slow current	495:517	a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	495:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	5	20	with	other	933:937	arg1	exercised					953:961	exercised	953:961	exercised	953:961	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	5	20	with	other	933:937	arg1	current					944:950	current	944:950	current (exercised)	944:962	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	0	21	from	Effects	0:6	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	22	theme	Nile	83:86	arg1	tilapia					88:94	Nile tilapia	83:94	Nile tilapia (Oreochromis niloticus)	83:118	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	22	theme	Nile	83:86	arg1	niloticus					109:117	Oreochromis niloticus	97:117	Oreochromis niloticus	97:117	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	8	23	theme	exercised	1301:1309	arg1	HSB					1311:1313	exercised HSB	1301:1313	exercised HSB	1301:1313	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	11	24	theme	drum	1669:1672	arg1	growth					1674:1679	red drum growth	1665:1679	red drum growth	1665:1679	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	8	25	located	observed	1289:1296	arg2	growth					1278:1283	Reduced growth	1270:1283	Reduced growth	1270:1283	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	8	25	located	observed	1289:1296	arg1	HSB					1311:1313	exercised HSB	1301:1313	exercised HSB	1301:1313	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	0	26	theme	sustained	11:19	arg1	exercise					30:37	sustained swimming exercise	11:37	sustained swimming exercise	11:37	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	3	27	theme	length/s	545:552	arg1	current					511:517	a constant slow current	495:517	a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	495:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	4	28	theme	Nile	691:694	arg1	tilapia					696:702	22 advanced juvenile male Nile tilapia	665:702	22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g)	665:721	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	28	theme	Nile	691:694	arg1	97.9 ± 2.4 g					709:720	Wt0 97.9 ± 2.4 g	705:720	Wt0 97.9 ± 2.4 g	705:720	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	0	29	theme	exercise	30:37	arg1	Effects					0:6	Effects	0:6	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).	0:209	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	1	30	theme	many	257:260	arg1	species					271:277	many salmonid species	257:277	many salmonid species	257:277	Exercise has been shown to increase growth of many salmonid species.					
36197539	9	31	theme	Hepatosomatic	1372:1384	arg1	index					1386:1390	Hepatosomatic index	1372:1390	Hepatosomatic index	1372:1390	Hepatosomatic index was lower in all exercised fish, though not significantly so for RD and tilapia.					
36197539	3	32	theme	present	355:361	arg1	study					363:367	The present study	351:367	The present study	351:367	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	10	33	theme	Significant	1473:1483	arg1	reductions					1485:1494	Significant reductions	1473:1494	Significant reductions	1473:1494	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	0	34	theme	growth	42:47	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	1	35	theme	species	271:277	arg1	growth					247:252	growth	247:252	growth of many salmonid species	247:277	Exercise has been shown to increase growth of many salmonid species.					
36197539	5	36	dep	static	908:913	arg1	control					916:922	control	916:922	control	916:922	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	5	37	theme	same	992:995	arg1	system					1023:1028	the same recirculating aquaculture system	988:1028	the same recirculating aquaculture system	988:1028	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	5	38	theme	fish	822:825	arg1	numbers					811:817	Equal numbers	805:817	Equal numbers of fish of each species	805:841	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	11	39	theme	body	1699:1702	arg1	composition					1704:1714	their body composition	1693:1714	their body composition	1693:1714	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	4	40	theme	juvenile	677:684	arg1	tilapia					696:702	22 advanced juvenile male Nile tilapia	665:702	22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g)	665:721	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	40	theme	juvenile	677:684	arg1	97.9 ± 2.4 g					709:720	Wt0 97.9 ± 2.4 g	705:720	Wt0 97.9 ± 2.4 g	705:720	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	5	41	theme	aquaculture	1011:1021	arg1	system					1023:1028	the same recirculating aquaculture system	988:1028	the same recirculating aquaculture system	988:1028	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	9	42	theme	exercised	1409:1417	arg1	fish					1419:1422	all exercised fish	1405:1422	all exercised fish	1405:1422	Hepatosomatic index was lower in all exercised fish, though not significantly so for RD and tilapia.					
36197539	3	43	theme	hybrid	428:433	arg1	HSB					449:451	HSB	449:451	HSB	449:451	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	3	43	theme	hybrid	428:433	arg1	bass					443:446	hybrid striped bass	428:446	hybrid striped bass (HSB)	428:452	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	0	44	theme	hybrid	157:162	arg1	bass					172:175	hybrid striped bass	157:175	hybrid striped bass (Morone chrysops × M. saxatilis)	157:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	44	theme	hybrid	157:162	arg1	saxatilis					199:207	Morone chrysops × M. saxatilis	178:207	Morone chrysops × M. saxatilis	178:207	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	3	45	theme	swimming	470:477	arg1	effects					459:465	the effects	455:465	the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	455:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	4	46	theme	red	736:738	arg1	74.9 ± 4.4 g					750:761	Wt0 74.9 ± 4.4 g	746:761	Wt0 74.9 ± 4.4 g	746:761	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	46	theme	red	736:738	arg1	drum					740:743	38 juvenile red drum	724:743	38 juvenile red drum (Wt0 74.9 ± 4.4 g)	724:762	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	0	47	theme	bass	172:175	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	10	48	theme	liver	1518:1522	arg1	glycogen					1524:1531	liver glycogen	1518:1531	liver glycogen of exercised tilapia and RD	1518:1559	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	5	49	dep	tagged	852:857	arg1	pit					848:850	pit	848:850	pit	848:850	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	0	50	theme	Morone	178:183	arg1	bass					172:175	hybrid striped bass	157:175	hybrid striped bass (Morone chrysops × M. saxatilis)	157:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	50	theme	Morone	178:183	arg1	saxatilis					199:207	Morone chrysops × M. saxatilis	178:207	Morone chrysops × M. saxatilis	178:207	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	10	51	theme	RD	1558:1559	arg1	glycogen					1524:1531	liver glycogen	1518:1531	liver glycogen of exercised tilapia and RD	1518:1559	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	10	52	theme	tilapia	1546:1552	arg1	glycogen					1524:1531	liver glycogen	1518:1531	liver glycogen of exercised tilapia and RD	1518:1559	Significant reductions also were detected in liver glycogen of exercised tilapia and RD.					
36197539	7	53	theme	weight	1183:1188	arg1	gain					1190:1193	weight gain	1183:1193	weight gain	1183:1193	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	3	54	theme	culture	611:617	arg1	system					619:624	a static culture system	602:624	a static culture system	602:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	0	55	theme	red	121:123	arg1	drum					125:128	red drum	121:128	red drum (Sciaenops ocellatus)	121:150	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	55	theme	red	121:123	arg1	ocellatus					141:149	Sciaenops ocellatus	131:149	Sciaenops ocellatus	131:149	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	8	56	theme	feeding	1354:1360	arg1	behavior					1362:1369	consistently skittish feeding behavior	1332:1369	consistently skittish feeding behavior	1332:1369	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	11	57	theme	continuous	1600:1609	arg1	exercise					1611:1618	continuous exercise	1600:1618	continuous exercise	1600:1618	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	7	58	theme	P ≤ 0.05	1157:1164	arg1	enhancements					1167:1178	Significant (P ≤ 0.05) enhancements	1144:1178	Significant (P ≤ 0.05) enhancements of weight gain	1144:1193	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	3	59	from	effects	459:465	arg1	current					511:517	a constant slow current	495:517	a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	495:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	6	60	theme	commercial	1072:1081	arg1	diet					1083:1086	a commercial diet	1070:1086	satiation twice daily a commercial diet	1048:1086	Fish were fed to satiation twice daily a commercial diet and individually weighed every 2 weeks through 7 weeks.					
36197539	7	61	theme	Significant	1144:1154	arg1	enhancements					1167:1178	Significant (P ≤ 0.05) enhancements	1144:1178	Significant (P ≤ 0.05) enhancements of weight gain	1144:1193	Significant (P ≤ 0.05) enhancements of weight gain were observed for exercised tilapia and RD vs static (control) treatments.					
36197539	0	62	theme	composition	58:68	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	3	63	theme	constant	497:504	arg1	current					511:517	a constant slow current	495:517	a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	495:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	8	64	theme	Reduced	1270:1276	arg1	growth					1278:1283	Reduced growth	1270:1283	Reduced growth	1270:1283	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	11	65	theme	tilapia	1653:1659	arg1	aspects					1642:1648	aspects	1642:1648	aspects of tilapia and red drum growth	1642:1679	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	0	66	theme	tilapia	88:94	arg1	responses					70:78	growth and body composition responses	42:78	growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis)	42:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	67	theme	chrysops × M.	185:197	arg1	bass					172:175	hybrid striped bass	157:175	hybrid striped bass (Morone chrysops × M. saxatilis)	157:208	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	67	theme	chrysops × M.	185:197	arg1	saxatilis					199:207	Morone chrysops × M. saxatilis	178:207	Morone chrysops × M. saxatilis	178:207	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	4	68	theme	Concurrent	627:636	arg1	trials					638:643	Concurrent trials	627:643	Concurrent trials	627:643	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	0	69	theme	Oreochromis	97:107	arg1	tilapia					88:94	Nile tilapia	83:94	Nile tilapia (Oreochromis niloticus)	83:118	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	0	69	theme	Oreochromis	97:107	arg1	niloticus					109:117	Oreochromis niloticus	97:117	Oreochromis niloticus	97:117	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	5	70	theme	Equal	805:809	arg1	numbers					811:817	Equal numbers	805:817	Equal numbers of fish of each species	805:841	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	4	71	theme	Wt0	786:788	arg1	HSB					781:783	20 juvenile HSB	769:783	20 juvenile HSB (Wt0 78.0 ± 3.2 g)	769:802	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	71	theme	Wt0	786:788	arg1	78.0 ± 3.2 g					790:801	Wt0 78.0 ± 3.2 g	786:801	Wt0 78.0 ± 3.2 g	786:801	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	2	72	theme	warmwater	332:340	arg1	species					342:348	warmwater species	332:348	warmwater species	332:348	However, limited research has evaluated exercise on warmwater species.					
36197539	0	73	theme	swimming	21:28	arg1	exercise					30:37	sustained swimming exercise	11:37	sustained swimming exercise	11:37	Effects of sustained swimming exercise on growth and body composition responses of Nile tilapia (Oreochromis niloticus), red drum (Sciaenops ocellatus), and hybrid striped bass (Morone chrysops × M. saxatilis).					
36197539	3	74	theme	body	540:543	arg1	1bl/s					555:559	1bl/s	555:559	1bl/s	555:559	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	3	74	theme	body	540:543	arg1	length/s					545:552	approximately one body length/s	522:552	approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system	522:624	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	5	75	theme	species	835:841	arg1	numbers					811:817	Equal numbers	805:817	Equal numbers of fish of each species	805:841	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	8	76	theme	skittish	1345:1352	arg1	behavior					1362:1369	consistently skittish feeding behavior	1332:1369	consistently skittish feeding behavior	1332:1369	Reduced growth was observed in exercised HSB, possibly due to consistently skittish feeding behavior.					
36197539	4	77	theme	male	686:689	arg1	tilapia					696:702	22 advanced juvenile male Nile tilapia	665:702	22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g)	665:721	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	77	theme	male	686:689	arg1	97.9 ± 2.4 g					709:720	Wt0 97.9 ± 2.4 g	705:720	Wt0 97.9 ± 2.4 g	705:720	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	3	78	theme	red	409:411	arg1	RD					419:420	RD	419:420	RD	419:420	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	3	78	theme	red	409:411	arg1	drum					413:416	red drum	409:416	red drum (RD)	409:421	The present study was conducted to evaluate with tilapia, red drum (RD), and hybrid striped bass (HSB), the effects of swimming (exercising) in a constant slow current of approximately one body length/s (1bl/s) compared to not being forced to swim in a static culture system.					
36197539	9	79	dep	significantly	1436:1448	arg1	so					1450:1451	so	1450:1451	so	1450:1451	Hepatosomatic index was lower in all exercised fish, though not significantly so for RD and tilapia.					
36197539	9	79	dep	significantly	1436:1448	arg1	not					1432:1434	not	1432:1434	not	1432:1434	Hepatosomatic index was lower in all exercised fish, though not significantly so for RD and tilapia.					
36197539	1	80	theme	salmonid	262:269	arg1	species					271:277	many salmonid species	257:277	many salmonid species	257:277	Exercise has been shown to increase growth of many salmonid species.					
36197539	5	81	dep	operated	899:906	arg1	static					908:913	static	908:913	static	908:913	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	2	82	theme	limited	289:295	arg1	research					297:304	limited research	289:304	limited research	289:304	However, limited research has evaluated exercise on warmwater species.					
36197539	5	83	theme	recirculating	997:1009	arg1	system					1023:1028	the same recirculating aquaculture system	988:1028	the same recirculating aquaculture system	988:1028	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
36197539	4	84	theme	advanced	668:675	arg1	tilapia					696:702	22 advanced juvenile male Nile tilapia	665:702	22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g)	665:721	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	4	84	theme	advanced	668:675	arg1	97.9 ± 2.4 g					709:720	Wt0 97.9 ± 2.4 g	705:720	Wt0 97.9 ± 2.4 g	705:720	Concurrent trials were conducted with 22 advanced juvenile male Nile tilapia (Wt0 97.9 ± 2.4 g), 38 juvenile red drum (Wt0 74.9 ± 4.4 g), and 20 juvenile HSB (Wt0 78.0 ± 3.2 g).					
36197539	11	85	theme	red	1665:1667	arg1	growth					1674:1679	red drum growth	1665:1679	red drum growth	1665:1679	Results from this study indicate that continuous exercise beneficially affected aspects of tilapia and red drum growth and altered their body composition.					
36197539	5	86	theme	system	1023:1028	arg1	part					980:983	all part	976:983	all part of the same recirculating aquaculture system	976:1028	Equal numbers of fish of each species were pit tagged and randomly assigned to two tanks, one operated static (control) and the other with current (exercised), which were all part of the same recirculating aquaculture system.					
37307972	7	0	theme	kinetic	1256:1262	arg1	model					1264:1268	Pseudo-Second-Order kinetic model	1236:1268	Pseudo-Second-Order kinetic model	1236:1268	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	1	1	theme	free	360:363	arg1	radical					365:371	free radical	360:371	free radical polymerization technique	360:396	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	8	2	theme	adsorptive	1372:1381	arg1	removal					1383:1389	the adsorptive removal	1368:1389	the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency	1368:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	5	3	with	dominant	908:915	arg1	capacity					953:960	a maximum adsorption capacity	932:960	a maximum adsorption capacity of 860 mg/g	932:972	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	1	4	theme	radical	365:371	arg1	technique					388:396	free radical polymerization technique	360:396	free radical polymerization technique	360:396	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	5	5	theme	maximum	934:940	arg1	capacity					953:960	a maximum adsorption capacity	932:960	a maximum adsorption capacity of 860 mg/g	932:972	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	0	6	from	solutions	162:170	arg1	removal					123:129	the removal	119:129	the removal of methylene blue from aqueous solutions	119:170	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	1	7	theme	polymerization	373:386	arg1	technique					388:396	free radical polymerization technique	360:396	free radical polymerization technique	360:396	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	8	8	theme	%	1466:1466	arg1	efficiency					1476:1485	92.4 % removal efficiency	1461:1485	92.4 % removal efficiency	1461:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	4	9	theme	adsorptive	809:818	arg1	removal					820:826	pH sensitive adsorptive removal	796:826	pH sensitive adsorptive removal of cationic dye (methylene blue)	796:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	1	10	theme	N-vinylimidazole	283:298	arg1	hydrogels					310:318	chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	251:318	hydrogels	310:318	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	7	11	theme	Pseudo-Second-Order	1236:1254	arg1	model					1264:1268	Pseudo-Second-Order kinetic model	1236:1268	Pseudo-Second-Order kinetic model	1236:1268	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	5	12	from	pH = 8	920:925	arg1	dominant					908:915	dominant	908:915	dominant	908:915	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	4	13	theme	sensitive	799:807	arg1	removal					820:826	pH sensitive adsorptive removal	796:826	pH sensitive adsorptive removal of cationic dye (methylene blue)	796:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	1	14	theme	composite	300:308	arg1	hydrogels					310:318	chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	251:318	hydrogels	310:318	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	2	15	theme	VSM	554:556	arg1	analysis					558:565	VSM analysis	554:565	VSM analysis	554:565	The prepared magnetic composite hydrogel was characterized by FT-IR, TGA, SEM, XRD, and VSM analysis.					
37307972	5	16	theme	adsorption	942:951	arg1	capacity					953:960	a maximum adsorption capacity	932:960	a maximum adsorption capacity of 860 mg/g	932:972	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	8	17	theme	blue	1404:1407	arg1	methylene					1394:1402	methylene blue	1394:1407	methylene blue	1394:1407	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	5	18	theme	blue	899:902	arg1	methylene					889:897	methylene blue	889:902	methylene blue	889:902	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	7	19	theme	blue	1171:1174	arg1	methylene					1161:1169	methylene blue	1161:1174	methylene blue	1161:1174	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	1	20	theme	ammonium	404:411	arg1	ethylenediamine					436:450	ammonium persulfate/tetramethyl ethylenediamine	404:450	ammonium persulfate/tetramethyl ethylenediamine	404:450	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	3	21	theme	swelling	570:577	arg1	study					579:583	A swelling study	568:583	A swelling study	568:583	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	1	22	theme	present	177:183	arg1	research					185:192	The present research	173:192	The present research	173:192	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	0	23	theme	modified	6:13	arg1	chitosan					15:22	Fe3O4 modified chitosan	0:22	Fe3O4 modified chitosan	0:22	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	1	24	theme	persulfate/tetramethyl	413:434	arg1	ethylenediamine					436:450	ammonium persulfate/tetramethyl ethylenediamine	404:450	ammonium persulfate/tetramethyl ethylenediamine	404:450	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	7	25	theme	Langmuir	1203:1210	arg1	adsorption					1212:1221	Langmuir adsorption	1203:1221	Langmuir adsorption isotherm	1203:1230	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	6	26	theme	blue	1017:1020	arg1	methylene					1007:1015	methylene blue	1007:1020	methylene blue	1007:1020	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	6	27	from	media	1035:1039	arg1	removal					996:1002	the adsorptive removal	981:1002	the adsorptive removal of methylene blue from aqueous media	981:1039	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	3	28	with	efficient	664:672	arg1	swelling					687:694	maximum swelling	679:694	maximum swelling	679:694	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	6	29	theme	methylene	1007:1015	arg1	removal					996:1002	the adsorptive removal	981:1002	the adsorptive removal of methylene blue from aqueous media	981:1039	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	4	30	theme	pH	796:797	arg1	removal					820:826	pH sensitive adsorptive removal	796:826	pH sensitive adsorptive removal of cationic dye (methylene blue)	796:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	2	31	theme	composite	488:496	arg1	hydrogel					498:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel was characterized by FT-IR, TGA, SEM, XRD, and VSM analysis.					
37307972	6	32	theme	magnet	1139:1144	arg1	use					1120:1122	the use	1116:1122	the use of an external magnet	1116:1144	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	6	33	theme	composite	1044:1052	arg1	hydrogel					1054:1061	a composite hydrogel	1042:1061	a composite hydrogel	1042:1061	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	3	34	theme	maximum	679:685	arg1	swelling					687:694	maximum swelling	679:694	maximum swelling	679:694	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	8	35	theme	consecutive	1415:1425	arg1	cycles					1449:1454	5 consecutive adsorption-desorption cycles	1413:1454	5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency	1413:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	9	36	theme	wastewater	1583:1592	arg1	treatment					1594:1602	wastewater treatment	1583:1602	wastewater treatment	1583:1602	Hence, CANFe-4 offers a promising recyclable, sustainable, robust, and efficient adsorbent for wastewater treatment.					
37307972	2	37	theme	magnetic	479:486	arg1	hydrogel					498:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel was characterized by FT-IR, TGA, SEM, XRD, and VSM analysis.					
37307972	0	38	theme	magnetic	43:50	arg1	hydrogel					62:69	co-polymeric magnetic composite hydrogel	30:69	co-polymeric magnetic composite hydrogel	30:69	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	8	39	with	cycles	1449:1454	arg1	efficiency					1476:1485	92.4 % removal efficiency	1461:1485	92.4 % removal efficiency	1461:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	0	40	theme	blue	144:147	arg1	methylene					134:142	methylene blue	134:147	methylene blue	134:147	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	2	41	theme	prepared	470:477	arg1	hydrogel					498:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel	466:505	The prepared magnetic composite hydrogel was characterized by FT-IR, TGA, SEM, XRD, and VSM analysis.					
37307972	0	42	theme	co-polymeric	30:41	arg1	hydrogel					62:69	co-polymeric magnetic composite hydrogel	30:69	co-polymeric magnetic composite hydrogel	30:69	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	6	43	theme	adsorptive	985:994	arg1	removal					996:1002	the adsorptive removal	981:1002	the adsorptive removal of methylene blue from aqueous media	981:1039	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	0	44	theme	methylene	134:142	arg1	removal					123:129	the removal	119:129	the removal of methylene blue from aqueous solutions	119:170	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	1	45	dep	comprises	194:202	arg1	CANFe-7					332:338	CANFe-7	332:338	CANFe-7	332:338	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	5	46	theme	methylene	889:897	arg1	adsorption					875:884	pH dependent adsorption	862:884	pH dependent adsorption of methylene blue	862:902	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	1	47	theme	magnetic	223:230	arg1	Fe3O4					232:236	magnetic Fe3O4	223:236	magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	223:318	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	7	48	theme	methylene	1161:1169	arg1	Adsorption					1147:1156	Adsorption	1147:1156	Adsorption of methylene blue	1147:1174	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	0	49	theme	aqueous	154:160	arg1	solutions					162:170	aqueous solutions	154:170	aqueous solutions	154:170	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	3	50	theme	swelling	617:624	arg1	behavior					626:633	the swelling behavior	613:633	the swelling behavior	613:633	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	1	51	dep	CANFe-7	332:338	arg1	to					329:330	to	329:330	to	329:330	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	4	52	theme	pHPZC	754:758	arg1	analysis					760:767	pHPZC analysis	754:767	pHPZC analysis	754:767	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	0	53	theme	composite	52:60	arg1	hydrogel					62:69	co-polymeric magnetic composite hydrogel	30:69	co-polymeric magnetic composite hydrogel	30:69	Fe3O4 modified chitosan based co-polymeric magnetic composite hydrogel: Synthesis, characterization and evaluation for the removal of methylene blue from aqueous solutions.					
37307972	7	54	dep	isotherm	1223:1230	arg1	the					1199:1201	the	1199:1201	the	1199:1201	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	3	55	theme	removal	709:715	arg1	studies					717:723	entire removal studies	702:723	entire removal studies	702:723	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	8	56	theme	92.4 	1461:1465	arg1	%					1466:1466	%	1466:1466	%	1466:1466	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	4	57	theme	dye	840:842	arg1	removal					820:826	pH sensitive adsorptive removal	796:826	pH sensitive adsorptive removal of cationic dye (methylene blue)	796:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	4	58	theme	blue	855:858	arg1	dye					840:842	cationic dye	831:842	cationic dye (methylene blue)	831:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	8	59	theme	adsorption-desorption	1427:1447	arg1	cycles					1449:1454	5 consecutive adsorption-desorption cycles	1413:1454	5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency	1413:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	1	60	theme	Fe3O4	232:236	arg1	fabrication					208:218	the fabrication	204:218	the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	204:318	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	8	61	theme	methylene	1394:1402	arg1	removal					1383:1389	the adsorptive removal	1368:1389	the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency	1368:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	4	62	theme	cationic	831:838	arg1	dye					840:842	cationic dye	831:842	cationic dye (methylene blue)	831:859	pHPZC analysis was performed to determine pH sensitive adsorptive removal of cationic dye (methylene blue).					
37307972	5	63	theme	860 mg/g	965:972	arg1	capacity					953:960	a maximum adsorption capacity	932:960	a maximum adsorption capacity of 860 mg/g	932:972	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	8	64	theme	removal	1468:1474	arg1	efficiency					1476:1485	92.4 % removal efficiency	1461:1485	92.4 % removal efficiency	1461:1485	Moreover, it was found that CANFe-4 could be frequently applied for the adsorptive removal of methylene blue for 5 consecutive adsorption-desorption cycles with 92.4 % removal efficiency.					
37307972	3	65	theme	entire	702:707	arg1	studies					717:723	entire removal studies	702:723	entire removal studies	702:723	A swelling study was performed to understand the swelling behavior and found CANFe-4 to be more efficient with maximum swelling hence entire removal studies were performed with CANFe-4.					
37307972	5	66	theme	dependent	865:873	arg1	adsorption					875:884	pH dependent adsorption	862:884	pH dependent adsorption of methylene blue	862:902	pH dependent adsorption of methylene blue was dominant at pH = 8 with a maximum adsorption capacity of 860 mg/g.					
37307972	6	67	theme	external	1130:1137	arg1	magnet					1139:1144	an external magnet	1127:1144	an external magnet	1127:1144	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	1	68	theme	chitosan	251:258	arg1	acrylamide					268:277	chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	251:318	acrylamide	268:277	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37307972	6	69	theme	aqueous	1027:1033	arg1	media					1035:1039	aqueous media	1027:1039	aqueous media	1027:1039	After the adsorptive removal of methylene blue from aqueous media, a composite hydrogel can conveniently be separated from the solution with the use of an external magnet.					
37307972	7	70	theme	adsorption	1212:1221	arg1	isotherm					1223:1230	Langmuir adsorption isotherm	1203:1230	Langmuir adsorption isotherm	1203:1230	Adsorption of methylene blue is well explained with the Langmuir adsorption isotherm and Pseudo-Second-Order kinetic model that validates chemisorption.					
37307972	9	71	dep	recyclable	1522:1531	arg1	adsorbent					1569:1577	adsorbent	1569:1577	adsorbent	1569:1577	Hence, CANFe-4 offers a promising recyclable, sustainable, robust, and efficient adsorbent for wastewater treatment.					
37307972	1	72	theme	grafted	260:266	arg1	acrylamide					268:277	chitosan grafted acrylamide and N-vinylimidazole composite hydrogels	251:318	acrylamide	268:277	The present research comprises the fabrication of magnetic Fe3O4 incorporated chitosan grafted acrylamide and N-vinylimidazole composite hydrogels (CANFe-1 to CANFe-7) via water mediated free radical polymerization technique using ammonium persulfate/tetramethyl ethylenediamine as initiator.					
37062380	2	0	theme	composite	501:509	arg1	films					511:515	a novel bioactive composite films	483:515	a novel bioactive composite films for food packaging application	483:546	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	6	1	theme	appropriate	972:982	arg1	%					993:993	2 %	991:993	2 %	991:993	ZPCO added at an appropriate level (2 %) can improve water-resistance of the films and reduce water vapor permeability.					
37062380	6	1	theme	appropriate	972:982	arg1	level					984:988	an appropriate level	969:988	an appropriate level (2 %)	969:994	ZPCO added at an appropriate level (2 %) can improve water-resistance of the films and reduce water vapor permeability.					
37062380	5	2	theme	tensile	799:805	arg1	strength					807:814	tensile strength	799:814	tensile strength	799:814	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	1	3	theme	increasing	268:277	arg1	attention					279:287	increasing attention	268:287	increasing attention	268:287	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	2	4	theme	bioactive	491:499	arg1	films					511:515	a novel bioactive composite films	483:515	a novel bioactive composite films for food packaging application	483:546	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	7	5	theme	food	1170:1173	arg1	simulants					1175:1183	food simulants	1170:1183	food simulants	1170:1183	More importantly, ZPCO can achieve a slower sustained-release of CEO from composite films into food simulants.					
37062380	9	6	theme	bioactive	1546:1554	arg1	material					1556:1563	a bioactive material	1544:1563	a bioactive material in the food packing	1544:1583	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	9	7	from	material	1556:1563	arg1	packing					1577:1583	the food packing	1568:1583	the food packing	1568:1583	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	2	8	theme	food	521:524	arg1	application					536:546	food packaging application	521:546	food packaging application	521:546	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	8	9	theme	composite	1203:1211	arg1	film					1213:1216	the composite film	1199:1216	the composite film containing 2 % ZPCO	1199:1236	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	8	9	theme	composite	1203:1211	arg1	safe					1241:1244	safe	1241:1244	safe	1241:1244	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	0	10	from	Effects	0:6	arg1	application					93:103	application	93:103	application	93:103	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	10	from	Effects	0:6	arg1	properties					78:87	properties	78:87	properties	78:87	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	10	from	Effects	0:6	arg1	structure					67:75	structure	67:75	structure	67:75	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	5	11	dep	decreased	857:865	arg1	whereas					868:874	whereas	868:874	whereas	868:874	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	6	12	theme	films	1032:1036	arg1	water-resistance					1008:1023	water-resistance	1008:1023	water-resistance of the films	1008:1036	ZPCO added at an appropriate level (2 %) can improve water-resistance of the films and reduce water vapor permeability.					
37062380	3	13	theme	long-term	604:612	arg1	stability					614:622	long-term stability	604:622	long-term stability	604:622	Results demonstrated that antibacterial ZPCO featuring long-term stability was successfully obtained.					
37062380	8	14	contain	containing	1218:1227	arg1	film					1213:1216	the composite film	1199:1216	the composite film containing 2 % ZPCO	1199:1236	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	8	14	contain	containing	1218:1227	arg1	safe					1241:1244	safe	1241:1244	safe	1241:1244	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	8	14	contain	containing	1218:1227	arg2	ZPCO					1233:1236	2 % ZPCO	1229:1236	2 % ZPCO	1229:1236	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	3	15	theme	antibacterial	575:587	arg1	ZPCO					589:592	antibacterial ZPCO	575:592	antibacterial ZPCO featuring long-term stability	575:622	Results demonstrated that antibacterial ZPCO featuring long-term stability was successfully obtained.					
37062380	9	16	theme	ZPCO	1484:1487	arg1	incorporation					1467:1479	the incorporation	1463:1479	the incorporation of ZPCO into CTS films	1463:1502	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	2	17	theme	packaging	526:534	arg1	application					536:546	food packaging application	521:546	food packaging application	521:546	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	7	18	theme	CEO	1140:1142	arg1	sustained-release					1119:1135	a slower sustained-release	1110:1135	a slower sustained-release of CEO from composite films into food simulants	1110:1183	More importantly, ZPCO can achieve a slower sustained-release of CEO from composite films into food simulants.					
37062380	2	19	theme	cinnamon	417:424	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	19	theme	cinnamon	417:424	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	1	20	theme	non-conventional	163:178	arg1	sources					187:193	non-conventional starch sources	163:193	non-conventional starch sources	163:193	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	0	21	theme	emulsion	51:58	arg1	Effects					0:6	Effects	0:6	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.	0:150	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	2	22	theme	novel	485:489	arg1	films					511:515	a novel bioactive composite films	483:515	a novel bioactive composite films for food packaging application	483:546	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	7	23	theme	slower	1112:1117	arg1	sustained-release					1119:1135	a slower sustained-release	1110:1135	a slower sustained-release of CEO from composite films into food simulants	1110:1183	More importantly, ZPCO can achieve a slower sustained-release of CEO from composite films into food simulants.					
37062380	8	24	theme	2 	1229:1230	arg1	%					1231:1231	%	1231:1231	%	1231:1231	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	1	25	theme	starch	180:185	arg1	sources					187:193	non-conventional starch sources	163:193	non-conventional starch sources	163:193	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	8	26	theme	%	1231:1231	arg1	ZPCO					1233:1236	2 % ZPCO	1229:1236	2 % ZPCO	1229:1236	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	5	27	theme	moisture	821:828	arg1	content					830:836	moisture content	821:836	moisture content	821:836	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	4	28	theme	favorable	698:706	arg1	dispersibility					708:721	favorable dispersibility	698:721	favorable dispersibility	698:721	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	2	29	theme	tuber	340:344	arg1	CTS					354:356	CTS	354:356	CTS	354:356	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	29	theme	tuber	340:344	arg1	starch					346:351	a nonconventional chayote tuber starch	314:351	a nonconventional chayote tuber starch (CTS)	314:357	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	1	30	theme	sources	187:193	arg1	use					156:158	The use	152:158	The use of non-conventional starch sources	152:193	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	5	31	theme	increasing	768:777	arg1	ZPCO					763:766	ZPCO increasing	763:777	ZPCO increasing	763:777	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	7	32	from	films	1159:1163	arg1	sustained-release					1119:1135	a slower sustained-release	1110:1135	a slower sustained-release of CEO from composite films into food simulants	1110:1183	More importantly, ZPCO can achieve a slower sustained-release of CEO from composite films into food simulants.					
37062380	2	33	theme	chayote	332:338	arg1	CTS					354:356	CTS	354:356	CTS	354:356	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	33	theme	chayote	332:338	arg1	starch					346:351	a nonconventional chayote tuber starch	314:351	a nonconventional chayote tuber starch (CTS)	314:357	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	34	theme	nanoparticle-stabilized	393:415	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	34	theme	nanoparticle-stabilized	393:415	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	0	35	theme	essential	20:28	arg1	emulsion					51:58	cinnamon essential oil-loaded Pickering emulsion	11:58	cinnamon essential oil-loaded Pickering emulsion	11:58	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	36	theme	starch-based	122:133	arg1	films					145:149	chayote tuber starch-based composite films	108:149	chayote tuber starch-based composite films	108:149	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	37	dep	structure	67:75	arg1	the					63:65	the	63:65	the	63:65	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	2	38	theme	Pickering	446:454	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	38	theme	Pickering	446:454	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	0	39	theme	cinnamon	11:18	arg1	emulsion					51:58	cinnamon essential oil-loaded Pickering emulsion	11:58	cinnamon essential oil-loaded Pickering emulsion	11:58	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	40	theme	tuber	116:120	arg1	films					145:149	chayote tuber starch-based composite films	108:149	chayote tuber starch-based composite films	108:149	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	8	41	theme	volatile	1387:1394	arg1	nitrogen					1401:1408	the lowest total volatile base nitrogen	1370:1408	the lowest total volatile base nitrogen	1370:1408	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	8	42	theme	total	1381:1385	arg1	nitrogen					1401:1408	the lowest total volatile base nitrogen	1370:1408	the lowest total volatile base nitrogen	1370:1408	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	4	43	theme	CTS	746:748	arg1	matrix					750:755	CTS matrix	746:755	CTS matrix	746:755	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	0	44	theme	Pickering	41:49	arg1	emulsion					51:58	cinnamon essential oil-loaded Pickering emulsion	11:58	cinnamon essential oil-loaded Pickering emulsion	11:58	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	45	theme	films	145:149	arg1	application					93:103	application	93:103	application	93:103	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	45	theme	films	145:149	arg1	properties					78:87	properties	78:87	properties	78:87	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	0	45	theme	films	145:149	arg1	structure					67:75	structure	67:75	structure	67:75	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	4	46	contain	have	693:696	arg1	ZPCO					688:691	ZPCO	688:691	ZPCO	688:691	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	4	46	contain	have	693:696	arg2	compatibility					727:739	compatibility	727:739	compatibility	727:739	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	4	46	contain	have	693:696	arg2	dispersibility					708:721	favorable dispersibility	698:721	favorable dispersibility	698:721	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	0	47	theme	chayote	108:114	arg1	films					145:149	chayote tuber starch-based composite films	108:149	chayote tuber starch-based composite films	108:149	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	8	48	theme	cell	1272:1275	arg1	cytotoxicity					1277:1288	cell cytotoxicity	1272:1288	cell cytotoxicity test	1272:1293	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	2	49	theme	CEO	441:443	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	49	theme	CEO	441:443	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	50	theme	oil	436:438	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	50	theme	oil	436:438	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	0	51	theme	oil-loaded	30:39	arg1	emulsion					51:58	cinnamon essential oil-loaded Pickering emulsion	11:58	cinnamon essential oil-loaded Pickering emulsion	11:58	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	5	52	from	break	896:900	arg1	elongation					882:891	their elongation	876:891	their elongation at break, antimicrobial and antioxidant activities	876:942	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	1	53	theme	bioactive	224:232	arg1	films					247:251	bioactive starch-based films	224:251	bioactive starch-based films	224:251	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	5	54	theme	composite	841:849	arg1	films					851:855	composite films	841:855	composite films	841:855	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	5	55	theme	antioxidant	921:931	arg1	activities					933:942	antioxidant activities	921:942	antioxidant activities	921:942	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	5	56	theme	films	851:855	arg1	content					830:836	moisture content	821:836	moisture content	821:836	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	5	56	theme	films	851:855	arg1	transmittance					784:796	transmittance	784:796	transmittance	784:796	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	5	56	theme	films	851:855	arg1	strength					807:814	tensile strength	799:814	tensile strength	799:814	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	9	57	theme	CTS	1494:1496	arg1	films					1498:1502	CTS films	1494:1502	CTS films	1494:1502	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	8	58	theme	lowest	1374:1379	arg1	nitrogen					1401:1408	the lowest total volatile base nitrogen	1370:1408	the lowest total volatile base nitrogen	1370:1408	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	0	59	theme	composite	135:143	arg1	films					145:149	chayote tuber starch-based composite films	108:149	chayote tuber starch-based composite films	108:149	Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.					
37062380	7	60	theme	composite	1149:1157	arg1	films					1159:1163	composite films	1149:1163	composite films into food simulants	1149:1183	More importantly, ZPCO can achieve a slower sustained-release of CEO from composite films into food simulants.					
37062380	8	61	theme	cytotoxicity	1277:1288	arg1	test					1290:1293	cell cytotoxicity test	1272:1293	cell cytotoxicity test	1272:1293	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	9	62	theme	great	1513:1517	arg1	application					1529:1539	a great potential application	1511:1539	a great potential application as a bioactive material in the food packing	1511:1583	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	2	63	theme	nonconventional	316:330	arg1	CTS					354:356	CTS	354:356	CTS	354:356	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	63	theme	nonconventional	316:330	arg1	starch					346:351	a nonconventional chayote tuber starch	314:351	a nonconventional chayote tuber starch (CTS)	314:357	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	1	64	theme	starch-based	234:245	arg1	films					247:251	bioactive starch-based films	224:251	bioactive starch-based films	224:251	The use of non-conventional starch sources to develop biodegradable and bioactive starch-based films have attracted increasing attention recently.					
37062380	5	65	dep	transmittance	784:796	arg1	the					780:782	the	780:782	the	780:782	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	9	66	theme	food	1572:1575	arg1	packing					1577:1583	the food packing	1568:1583	the food packing	1568:1583	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	8	67	theme	sensory	1430:1436	arg1	characteristic					1438:1451	sensory characteristic	1430:1451	sensory characteristic	1430:1451	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	9	68	theme	potential	1519:1527	arg1	application					1529:1539	a great potential application	1511:1539	a great potential application as a bioactive material in the food packing	1511:1583	Overall, the incorporation of ZPCO into CTS films offers a great potential application as a bioactive material in the food packing.					
37062380	8	69	theme	beef	1354:1357	arg1	life					1339:1342	the shelf life	1329:1342	the shelf life of ground beef	1329:1357	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	4	70	theme	FTIR	651:654	arg1	analyses					664:671	FTIR and SEM analyses	651:671	FTIR and SEM analyses	651:671	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
37062380	8	71	theme	base	1396:1399	arg1	nitrogen					1401:1408	the lowest total volatile base nitrogen	1370:1408	the lowest total volatile base nitrogen	1370:1408	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	5	72	from	activities	933:942	arg1	elongation					882:891	their elongation	876:891	their elongation at break, antimicrobial and antioxidant activities	876:942	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	2	73	theme	zein-pectin	381:391	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	73	theme	zein-pectin	381:391	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	74	theme	essential	426:434	arg1	ZPCO					466:469	ZPCO	466:469	ZPCO	466:469	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	2	74	theme	essential	426:434	arg1	emulsion					456:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion	381:463	zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO)	381:470	In this study, a nonconventional chayote tuber starch (CTS) was functionalized by zein-pectin nanoparticle-stabilized cinnamon essential oil (CEO) Pickering emulsion (ZPCO) to develop a novel bioactive composite films for food packaging application.					
37062380	6	75	theme	vapor	1055:1059	arg1	permeability					1061:1072	water vapor permeability	1049:1072	water vapor permeability	1049:1072	ZPCO added at an appropriate level (2 %) can improve water-resistance of the films and reduce water vapor permeability.					
37062380	6	76	theme	water	1049:1053	arg1	permeability					1061:1072	water vapor permeability	1049:1072	water vapor permeability	1049:1072	ZPCO added at an appropriate level (2 %) can improve water-resistance of the films and reduce water vapor permeability.					
37062380	5	77	from	antimicrobial	903:915	arg1	elongation					882:891	their elongation	876:891	their elongation at break, antimicrobial and antioxidant activities	876:942	With ZPCO increasing, the transmittance, tensile strength, and moisture content of composite films decreased, whereas their elongation at break, antimicrobial and antioxidant activities increased.					
37062380	8	78	theme	shelf	1333:1337	arg1	life					1339:1342	the shelf life	1329:1342	the shelf life of ground beef	1329:1357	Furthermore, the composite film containing 2 % ZPCO is safe and nontoxic as proved by cell cytotoxicity test, and it can significantly prolong the shelf life of ground beef by showing the lowest total volatile base nitrogen and best acceptable sensory characteristic.					
37062380	4	79	theme	SEM	660:662	arg1	analyses					664:671	FTIR and SEM analyses	651:671	FTIR and SEM analyses	651:671	FTIR and SEM analyses suggested that ZPCO have favorable dispersibility and compatibility with CTS matrix.					
35741032	12	0	located	observed	1461:1468	arg1	mice					1473:1476	mice	1473:1476	mice with colitis	1473:1489	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	12	0	located	observed	1461:1468	arg2	Alteration					1428:1437	Alteration	1428:1437	Alteration of gut microbiota	1428:1455	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	10	1	theme	molecule	1215:1222	arg1	frequency					1172:1180	the frequency	1168:1180	the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1168:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	1	2	with	disease	223:229	arg1	etiology					244:251	unknown etiology	236:251	unknown etiology	236:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	11	3	theme	IL-1β	1396:1400	arg1	levels					1402:1407	IL-1β levels	1396:1407	IL-1β levels	1396:1407	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	9	4	theme	DSS-induced	970:980	arg1	colitis					982:988	DSS-induced colitis	970:988	DSS-induced colitis mice treated with T. halophilus	970:1020	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	12	5	theme	halophilus	1518:1527	arg1	administration					1497:1510	administration	1497:1510	administration of T. halophilus	1497:1527	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	11	6	with	mice	1344:1347	arg1	colitis					1354:1360	colitis	1354:1360	colitis	1354:1360	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	10	7	theme	blood	1243:1247	arg1	leukocytes					1249:1258	peripheral blood leukocytes	1232:1258	peripheral blood leukocytes	1232:1258	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	0	8	theme	Dendritic	112:120	arg1	Activation					127:136	Dendritic Cell Activation	112:136	Dendritic Cell Activation	112:136	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	11	9	theme	cells	1325:1329	arg1	Frequencies					1299:1309	Frequencies	1299:1309	Frequencies of CD8+NK1.1+ cells	1299:1329	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	13	10	theme	microbiome	1660:1669	arg1	compositions					1671:1682	gut microbiome compositions	1656:1682	gut microbiome compositions	1656:1682	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	8	11	theme	metagenomic	948:958	arg1	analysis					960:967	16S rRNA metagenomic analysis	939:967	16S rRNA metagenomic analysis	939:967	Gut microbial composition was analyzed by 16S rRNA metagenomic analysis.					
35741032	10	12	theme	peripheral	1232:1241	arg1	leukocytes					1249:1258	peripheral blood leukocytes	1232:1258	peripheral blood leukocytes	1232:1258	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	12	13	theme	microbiota	1446:1455	arg1	Alteration					1428:1437	Alteration	1428:1437	Alteration of gut microbiota	1428:1455	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	8	14	theme	microbial	901:909	arg1	composition					911:921	Gut microbial composition	897:921	Gut microbial composition	897:921	Gut microbial composition was analyzed by 16S rRNA metagenomic analysis.					
35741032	7	15	theme	flow	861:864	arg1	cytometry					866:874	flow cytometry	861:874	flow cytometry	861:874	Anti-inflammatory functions were subsequently evaluated by flow cytometry, qRT-PCT, and ELISA.					
35741032	5	16	theme	drinking	727:734	arg1	water					736:740	drinking water	727:740	drinking water	727:740	Colitis was induced in C57BL/6J mice by feeding 4% DSS in drinking water for 7 days.					
35741032	10	17	from	lymphocytes	1286:1296	arg1	frequency					1172:1180	the frequency	1168:1180	the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1168:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	10	18	theme	intestinal	1264:1273	arg1	lymphocytes					1286:1296	intestinal epithelial lymphocytes	1264:1296	intestinal epithelial lymphocytes	1264:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	3	19	theme	salt	438:441	arg1	concentrations					443:456	high salt concentrations	433:456	high salt concentrations	433:456	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	0	20	theme	Cell	122:125	arg1	Activation					127:136	Dendritic Cell Activation	112:136	Dendritic Cell Activation	112:136	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	10	21	from	frequency	1172:1180	arg1	lymphocytes					1286:1296	intestinal epithelial lymphocytes	1264:1296	intestinal epithelial lymphocytes	1264:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	10	21	from	frequency	1172:1180	arg1	leukocytes					1249:1258	peripheral blood leukocytes	1232:1258	peripheral blood leukocytes	1232:1258	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	3	22	with	environments	415:426	arg1	concentrations					443:456	high salt concentrations	433:456	high salt concentrations	433:456	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	13	23	theme	gut	1656:1658	arg1	compositions					1671:1682	gut microbiome compositions	1656:1682	gut microbiome compositions	1656:1682	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	3	24	theme	acid-producing	373:386	arg1	halophilus					334:343	Tetragenococcus halophilus	318:343	Tetragenococcus halophilus (T. halophilus)	318:359	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	3	24	theme	acid-producing	373:386	arg1	bacterium					388:396	a lactic acid-producing bacterium	364:396	a lactic acid-producing bacterium that survives in environments with high salt concentrations	364:456	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	0	25	from	Inflammation	49:60	arg1	Mice					65:68	Mice	65:68	Mice	65:68	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	13	26	theme	immune	1634:1639	arg1	regulation					1641:1650	immune regulation	1634:1650	immune regulation	1634:1650	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	9	27	theme	DSS-induced	1106:1116	arg1	colitis					1118:1124	DSS-induced colitis	1106:1124	DSS-induced colitis mice	1106:1129	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	0	28	theme	Tetragenococcus	0:14	arg1	halophilus					16:25	Tetragenococcus halophilus	0:25	Tetragenococcus halophilus	0:25	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	4	29	theme	study	554:558	arg1	purpose					538:544	The purpose	534:544	The purpose of this study	534:558	The purpose of this study is to determine whether T. halophilus exerts an anti-inflammatory effect on intestinal inflammation in mice.					
35741032	9	30	theme	colitis	1118:1124	arg1	mice					1126:1129	DSS-induced colitis mice	1106:1129	DSS-induced colitis mice	1106:1129	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	3	31	theme	high	433:436	arg1	concentrations					443:456	high salt concentrations	433:456	high salt concentrations	433:456	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	0	32	theme	Intestinal	38:47	arg1	Inflammation					49:60	Intestinal Inflammation	38:60	Intestinal Inflammation in Mice	38:68	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	12	33	with	mice	1473:1476	arg1	colitis					1483:1489	colitis	1483:1489	colitis	1483:1489	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	12	34	theme	gut	1442:1444	arg1	microbiota					1446:1455	gut microbiota	1442:1455	gut microbiota	1442:1455	Alteration of gut microbiota was observed in mice with colitis after administration of T. halophilus.					
35741032	4	35	from	inflammation	647:658	arg1	mice					663:666	mice	663:666	mice	663:666	The purpose of this study is to determine whether T. halophilus exerts an anti-inflammatory effect on intestinal inflammation in mice.					
35741032	1	36	theme	major	186:190	arg1	subtypes					192:199	the major subtypes	182:199	the major subtypes of inflammatory bowel disease with unknown etiology	182:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	3	37	theme	lactic	366:371	arg1	halophilus					334:343	Tetragenococcus halophilus	318:343	Tetragenococcus halophilus (T. halophilus)	318:359	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	3	37	theme	lactic	366:371	arg1	bacterium					388:396	a lactic acid-producing bacterium	364:396	a lactic acid-producing bacterium that survives in environments with high salt concentrations	364:456	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	8	38	theme	Gut	897:899	arg1	composition					911:921	Gut microbial composition	897:921	Gut microbial composition	897:921	Gut microbial composition was analyzed by 16S rRNA metagenomic analysis.					
35741032	7	39	theme	Anti-inflammatory	802:818	arg1	functions					820:828	Anti-inflammatory functions	802:828	Anti-inflammatory functions	802:828	Anti-inflammatory functions were subsequently evaluated by flow cytometry, qRT-PCT, and ELISA.					
35741032	1	40	theme	subtypes	192:199	arg1	subtypes					192:199	the major subtypes	182:199	the major subtypes of inflammatory bowel disease with unknown etiology	182:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	1	40	theme	subtypes	192:199	arg1	one					175:177	one	175:177	one	175:177	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	13	41	from	colitis	1606:1612	arg1	mice					1617:1620	mice	1617:1620	mice	1617:1620	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	3	42	dep	halophilus	334:343	arg1	halophilus					349:358	T. halophilus	346:358	T. halophilus	346:358	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	8	43	theme	16S	939:941	arg1	analysis					960:967	16S rRNA metagenomic analysis	939:967	16S rRNA metagenomic analysis	939:967	Gut microbial composition was analyzed by 16S rRNA metagenomic analysis.					
35741032	10	44	theme	dendritic	1189:1197	arg1	molecule					1215:1222	the dendritic cell activation molecule CD83	1185:1227	the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1185:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	5	45	theme	%	718:718	arg1	DSS					720:722	4% DSS	717:722	4% DSS in drinking water for 7 days	717:751	Colitis was induced in C57BL/6J mice by feeding 4% DSS in drinking water for 7 days.					
35741032	5	46	from	DSS	720:722	arg1	water					736:740	drinking water	727:740	drinking water	727:740	Colitis was induced in C57BL/6J mice by feeding 4% DSS in drinking water for 7 days.					
35741032	9	47	theme	colitis	982:988	arg1	mice					990:993	DSS-induced colitis mice	970:993	DSS-induced colitis mice treated with T. halophilus	970:1020	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	1	48	theme	inflammatory	204:215	arg1	disease					223:229	inflammatory bowel disease	204:229	inflammatory bowel disease with unknown etiology	204:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	10	49	theme	cell	1199:1202	arg1	molecule					1215:1222	the dendritic cell activation molecule CD83	1185:1227	the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1185:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	10	50	from	leukocytes	1249:1258	arg1	frequency					1172:1180	the frequency	1168:1180	the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1168:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	10	51	from	molecule	1215:1222	arg1	lymphocytes					1286:1296	intestinal epithelial lymphocytes	1264:1296	intestinal epithelial lymphocytes	1264:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	10	51	from	molecule	1215:1222	arg1	leukocytes					1249:1258	peripheral blood leukocytes	1232:1258	peripheral blood leukocytes	1232:1258	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	11	52	dep	T.	1368:1369	arg1	halophilus					1371:1380	halophilus	1371:1380	halophilus	1371:1380	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	11	53	theme	CD8+NK1.1+	1314:1323	arg1	cells					1325:1329	CD8+NK1.1+ cells	1314:1329	CD8+NK1.1+ cells	1314:1329	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	11	54	theme	T.	1368:1369	arg1	treatment					1382:1390	T. halophilus treatment	1368:1390	T. halophilus treatment	1368:1390	Frequencies of CD8+NK1.1+ cells decreased in mice with colitis after T. halophilus treatment and IL-1β levels were also reduced.					
35741032	3	55	theme	immunomodulatory	492:507	arg1	function					509:516	its immunomodulatory function	488:516	its immunomodulatory function	488:516	Tetragenococcus halophilus (T. halophilus) is a lactic acid-producing bacterium that survives in environments with high salt concentrations, though little is known about its immunomodulatory function as a probiotic.					
35741032	5	56	theme	C57BL/6J	692:699	arg1	mice					701:704	C57BL/6J mice	692:704	C57BL/6J mice	692:704	Colitis was induced in C57BL/6J mice by feeding 4% DSS in drinking water for 7 days.					
35741032	10	57	theme	epithelial	1275:1284	arg1	lymphocytes					1286:1296	intestinal epithelial lymphocytes	1264:1296	intestinal epithelial lymphocytes	1264:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	1	58	theme	bowel	217:221	arg1	disease					223:229	inflammatory bowel disease	204:229	inflammatory bowel disease with unknown etiology	204:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	13	59	dep	suggest	1544:1550	arg1	effective					1569:1577	effective	1569:1577	effective	1569:1577	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	8	60	theme	rRNA	943:946	arg1	analysis					960:967	16S rRNA metagenomic analysis	939:967	16S rRNA metagenomic analysis	939:967	Gut microbial composition was analyzed by 16S rRNA metagenomic analysis.					
35741032	1	61	theme	Ulcerative	148:157	arg1	UC					168:169	UC	168:169	UC	168:169	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	1	61	theme	Ulcerative	148:157	arg1	colitis					159:165	Ulcerative colitis	148:165	Ulcerative colitis (UC)	148:170	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	9	62	theme	weight	1034:1039	arg1	loss					1041:1044	less weight loss	1029:1044	less weight loss	1029:1044	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	1	63	theme	disease	223:229	arg1	subtypes					192:199	the major subtypes	182:199	the major subtypes of inflammatory bowel disease with unknown etiology	182:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
35741032	0	64	theme	Gut	82:84	arg1	Microbiota					86:95	Gut Microbiota	82:95	Gut Microbiota	82:95	Tetragenococcus halophilus Alleviates Intestinal Inflammation in Mice by Altering Gut Microbiota and Regulating Dendritic Cell Activation via CD83.					
35741032	9	65	theme	colonic	1075:1081	arg1	shortening					1083:1092	colonic shortening	1075:1092	colonic shortening	1075:1092	DSS-induced colitis mice treated with T. halophilus showed less weight loss and significantly suppressed colonic shortening compared to DSS-induced colitis mice.					
35741032	13	66	theme	DSS-induced	1594:1604	arg1	colitis					1606:1612	DSS-induced colitis	1594:1612	DSS-induced colitis in mice	1594:1620	These results suggest T. halophilus is effective in alleviating DSS-induced colitis in mice by altering immune regulation and gut microbiome compositions.					
35741032	4	67	theme	intestinal	636:645	arg1	inflammation					647:658	intestinal inflammation	636:658	intestinal inflammation in mice	636:666	The purpose of this study is to determine whether T. halophilus exerts an anti-inflammatory effect on intestinal inflammation in mice.					
35741032	10	68	theme	activation	1204:1213	arg1	molecule					1215:1222	the dendritic cell activation molecule CD83	1185:1227	the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes	1185:1296	T. halophilus significantly reduced the frequency of the dendritic cell activation molecule CD83 in peripheral blood leukocytes and intestinal epithelial lymphocytes.					
35741032	4	69	theme	anti-inflammatory	608:624	arg1	effect					626:631	an anti-inflammatory effect	605:631	an anti-inflammatory effect	605:631	The purpose of this study is to determine whether T. halophilus exerts an anti-inflammatory effect on intestinal inflammation in mice.					
35741032	1	70	theme	unknown	236:242	arg1	etiology					244:251	unknown etiology	236:251	unknown etiology	236:251	Ulcerative colitis (UC) is one of the major subtypes of inflammatory bowel disease with unknown etiology.					
37201514	10	0	from	nature	1585:1590	arg1	MWCNT					1612:1616	MWCNT	1612:1616	MWCNT	1612:1616	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	10	1	theme	diffraction	1539:1549	arg1	analysis					1557:1564	X-ray diffraction (XRD) analysis	1533:1564	X-ray diffraction (XRD) analysis	1533:1564	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	13	2	dep	ID	2076:2077	arg1	1HJV					2080:2083	1HJV	2080:2083	1HJV	2080:2083	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	13	2	dep	ID	2076:2077	arg1	1ALU					2089:2092	1ALU	2089:2092	1ALU	2089:2092	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	7	3	theme	PDB	1111:1113	arg1	1ALU					1125:1128	1ALU	1125:1128	1ALU	1125:1128	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	7	3	theme	PDB	1111:1113	arg1	ID					1115:1116	PDB ID	1111:1116	PDB ID	1111:1116	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	9	4	theme	keratin	1448:1454	arg1	presence					1436:1443	the presence	1432:1443	the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite	1432:1510	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	11	5	contain	has	1737:1739	arg2	temperature					1770:1780	a high thermal decomposition temperature	1741:1780	a high thermal decomposition temperature of 420° C	1741:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	11	5	contain	has	1737:1739	arg1	nanocomposite					1723:1735	the nanocomposite	1719:1735	the nanocomposite	1719:1735	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	9	6	attach	presence	1436:1443	arg2	sulfate					1483:1489	glucosamine sulfate	1471:1489	glucosamine sulfate	1471:1489	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	9	6	attach	presence	1436:1443	arg1	nanocomposite					1498:1510	the nanocomposite	1494:1510	the nanocomposite	1494:1510	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	9	6	attach	presence	1436:1443	arg2	chitosan					1457:1464	chitosan	1457:1464	chitosan	1457:1464	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	9	6	attach	presence	1436:1443	arg2	keratin					1448:1454	keratin	1448:1454	keratin	1448:1454	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	2	7	theme	challenges	306:315	arg1	design					403:408	the current drug design	386:408	the current drug design utilizing functional polymers	386:438	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	7	theme	challenges	306:315	arg1	challenges					306:315	the most critical challenges	288:315	the most critical challenges for improving the therapeutic effect in osteoarthritis treatments	288:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	7	theme	challenges	306:315	arg1	One					281:283	One	281:283	One	281:283	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	9	8	theme	chitosan	1457:1464	arg1	presence					1436:1443	the presence	1432:1443	the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite	1432:1510	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	8	9	theme	Emission	1189:1196	arg1	FESEM					1228:1232	FESEM	1228:1232	FESEM	1228:1232	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	8	9	theme	Emission	1189:1196	arg1	Microscope					1216:1225	Field Emission Scanning Electron Microscope	1183:1225	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	11	10	theme	C	1790:1790	arg1	temperature					1770:1780	a high thermal decomposition temperature	1741:1780	a high thermal decomposition temperature of 420° C	1741:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	8	11	theme	Electron	1207:1214	arg1	FESEM					1228:1232	FESEM	1228:1232	FESEM	1228:1232	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	8	11	theme	Electron	1207:1214	arg1	Microscope					1216:1225	Field Emission Scanning Electron Microscope	1183:1225	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	7	12	dep	proteins	1101:1108	arg1	1ALU					1125:1128	1ALU	1125:1128	1ALU	1125:1128	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	7	12	dep	proteins	1101:1108	arg1	ID					1115:1116	PDB ID	1111:1116	PDB ID	1111:1116	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	7	13	theme	docking	1031:1037	arg1	analysis					1039:1046	Molecular docking analysis	1021:1046	Molecular docking analysis	1021:1046	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	5	14	theme	potential	859:867	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	14	theme	potential	859:867	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	12	15	theme	MWCNT-GLS/KRT/CS	1924:1939	arg1	nanocomposite					1941:1953	MWCNT-GLS/KRT/CS nanocomposite	1924:1953	MWCNT-GLS/KRT/CS nanocomposite	1924:1953	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	4	16	theme	disease	694:700	arg1	progression					702:712	disease progression	694:712	disease progression	694:712	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	6	17	theme	various	952:958	arg1	ratios					960:965	various ratios	952:965	various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT	952:1018	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	11	18	theme	high	1743:1746	arg1	temperature					1770:1780	a high thermal decomposition temperature	1741:1780	a high thermal decomposition temperature of 420° C	1741:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	13	19	theme	protein	2053:2059	arg1	structure					2061:2069	each protein structure	2048:2069	each protein structure (PDB ID: 1HJV and 1ALU)	2048:2093	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	5	20	theme	osteoarthritis	898:911	arg1	treatment					885:893	the treatment	881:893	the treatment of osteoarthritis	881:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	8	21	theme	functionalized	1311:1324	arg1	nanotubes					1346:1354	functionalized multi-walled carbon nanotubes	1311:1354	functionalized multi-walled carbon nanotubes	1311:1354	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	5	22	theme	sulfate	776:782	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	22	theme	sulfate	776:782	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	22	theme	sulfate	776:782	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	8	23	theme	carbon	1339:1344	arg1	nanotubes					1346:1354	functionalized multi-walled carbon nanotubes	1311:1354	functionalized multi-walled carbon nanotubes	1311:1354	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	11	24	theme	decomposition	1756:1768	arg1	temperature					1770:1780	a high thermal decomposition temperature	1741:1780	a high thermal decomposition temperature of 420° C	1741:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	0	25	theme	drug	114:117	arg1	delivery					119:126	osteoarthritis drug delivery	99:126	osteoarthritis drug delivery	99:126	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	6	26	theme	sulfate	1001:1007	arg1	ratios					960:965	various ratios	952:965	various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT	952:1018	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	0	27	theme	sulfate	55:61	arg1	composite					63:71	keratin/chitosan/glucosamine sulfate composite	26:71	keratin/chitosan/glucosamine sulfate composite	26:71	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	9	28	dep	Fourier	1369:1375	arg1	Transform					1377:1385	Transform	1377:1385	Transform Infrared spectroscopy (FTIR)	1377:1414	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	2	29	theme	current	390:396	arg1	design					403:408	the current drug design	386:408	the current drug design utilizing functional polymers	386:438	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	29	theme	current	390:396	arg1	challenges					306:315	the most critical challenges	288:315	the most critical challenges for improving the therapeutic effect in osteoarthritis treatments	288:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	29	theme	current	390:396	arg1	One					281:283	One	281:283	One	281:283	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	7	30	theme	binding	1148:1154	arg1	affinity					1156:1163	the binding affinity	1144:1163	the binding affinity	1144:1163	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	9	31	from	presence	1436:1443	arg1	nanocomposite					1498:1510	the nanocomposite	1494:1510	the nanocomposite	1494:1510	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	13	32	dep	structure	2061:2069	arg1	ID					2076:2077	PDB ID	2072:2077	PDB ID: 1HJV and 1ALU	2072:2092	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	1	33	dep	cartilage	193:201	arg1	the					189:191	the	189:191	the	189:191	Osteoarthritis (OA) is an inflammatory disease that affects the cartilage and tissues around the joints, which results in excessive pain and stiffness.					
37201514	2	34	theme	functional	420:429	arg1	polymers					431:438	functional polymers	420:438	functional polymers	420:438	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	0	35	theme	keratin/chitosan/glucosamine	26:53	arg1	composite					63:71	keratin/chitosan/glucosamine sulfate composite	26:71	keratin/chitosan/glucosamine sulfate composite	26:71	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	5	36	theme	loaded	794:799	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	36	theme	loaded	794:799	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	36	theme	loaded	794:799	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	10	37	theme	X-ray	1533:1537	arg1	XRD					1552:1554	XRD	1552:1554	XRD	1552:1554	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	10	37	theme	X-ray	1533:1537	arg1	diffraction					1539:1549	X-ray diffraction	1533:1549	X-ray diffraction (XRD) analysis	1533:1564	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	13	38	theme	excellent	2001:2009	arg1	affinity					2019:2026	the excellent binding affinity	1997:2026	the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU)	1997:2093	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	3	39	theme	novel	487:491	arg1	need					460:463	a need	458:463	a need to design	458:473	Indeed, there is a need to design and develop novel therapeutic drugs for positive outcomes.					
37201514	3	39	theme	novel	487:491	arg1	drugs					505:509	novel therapeutic drugs	487:509	novel therapeutic drugs for positive outcomes	487:531	Indeed, there is a need to design and develop novel therapeutic drugs for positive outcomes.					
37201514	5	40	theme	multi-walled	816:827	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	40	theme	multi-walled	816:827	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	40	theme	multi-walled	816:827	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	1	41	theme	inflammatory	155:166	arg1	disease					168:174	an inflammatory disease	152:174	an inflammatory disease that affects the cartilage and tissues around the joints, which results in excessive pain and stiffness	152:278	Osteoarthritis (OA) is an inflammatory disease that affects the cartilage and tissues around the joints, which results in excessive pain and stiffness.					
37201514	1	41	theme	inflammatory	155:166	arg1	Osteoarthritis					129:142	Osteoarthritis	129:142	Osteoarthritis (OA)	129:147	Osteoarthritis (OA) is an inflammatory disease that affects the cartilage and tissues around the joints, which results in excessive pain and stiffness.					
37201514	13	42	theme	docking	1972:1978	arg1	results					1980:1986	molecular docking results	1962:1986	molecular docking results	1962:1986	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	3	43	theme	positive	515:522	arg1	outcomes					524:531	positive outcomes	515:531	positive outcomes	515:531	Indeed, there is a need to design and develop novel therapeutic drugs for positive outcomes.					
37201514	4	44	dep	potential	628:636	arg1	therapeutic					638:648	therapeutic	638:648	therapeutic	638:648	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	12	45	theme	MTT	1797:1799	arg1	results					1807:1813	The MTT assay results	1793:1813	The MTT assay results	1793:1813	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	10	46	theme	composite	1599:1607	arg1	nature					1585:1590	the nature	1581:1590	the nature of the composite in MWCNT	1581:1616	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	5	47	theme	Keratin/Chitosan/Glucosamine	747:774	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	47	theme	Keratin/Chitosan/Glucosamine	747:774	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	47	theme	Keratin/Chitosan/Glucosamine	747:774	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	2	48	theme	osteoarthritis	357:370	arg1	treatments					372:381	osteoarthritis treatments	357:381	osteoarthritis treatments	357:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	1	49	theme	excessive	251:259	arg1	pain					261:264	excessive pain	251:264	excessive pain	251:264	Osteoarthritis (OA) is an inflammatory disease that affects the cartilage and tissues around the joints, which results in excessive pain and stiffness.					
37201514	10	50	from	composite	1599:1607	arg1	MWCNT					1612:1616	MWCNT	1612:1616	MWCNT	1612:1616	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	10	51	from	MWCNT	1612:1616	arg1	nature					1585:1590	the nature	1581:1590	the nature of the composite in MWCNT	1581:1616	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	2	52	from	effect	347:352	arg1	treatments					372:381	osteoarthritis treatments	357:381	osteoarthritis treatments	357:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	11	53	theme	Thermogravimetric	1672:1688	arg1	analysis					1696:1703	Thermogravimetric (TGA) analysis	1672:1703	Thermogravimetric (TGA) analysis	1672:1703	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	4	54	from	effects	650:656	arg1	ability					675:681	ability	675:681	ability to inhibit disease progression	675:712	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	4	54	from	effects	650:656	arg1	cartilage					661:669	cartilage	661:669	cartilage	661:669	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	0	55	theme	composite	63:71	arg1	development					11:21	development	11:21	development	11:21	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	0	55	theme	composite	63:71	arg1	Design					0:5	Design	0:5	Design	0:5	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	4	56	theme	potential	628:636	arg1	effects					650:656	its potential therapeutic effects	624:656	its potential therapeutic effects on cartilage and ability to inhibit disease progression	624:712	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	7	57	dep	ID	1115:1116	arg1	1HJV					1119:1122	1HJV	1119:1122	1HJV	1119:1122	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	7	58	theme	targeted	1092:1099	arg1	proteins					1101:1108	targeted proteins	1092:1108	targeted proteins (PDB ID: 1HJV, 1ALU)	1092:1129	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	12	59	theme	nanocomposite	1941:1953	arg1	500μg/ml					1911:1918	500μg/ml	1911:1918	500μg/ml	1911:1918	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	12	59	theme	nanocomposite	1941:1953	arg1	concentration					1896:1908	the maximum concentration	1884:1908	the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite	1884:1953	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	6	60	theme	Glucosamine	989:999	arg1	sulfate					1001:1007	Glucosamine sulfate	989:1007	Glucosamine sulfate	989:1007	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	2	61	theme	critical	297:304	arg1	challenges					306:315	the most critical challenges	288:315	the most critical challenges for improving the therapeutic effect in osteoarthritis treatments	288:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	8	62	theme	Field	1183:1187	arg1	FESEM					1228:1232	FESEM	1228:1232	FESEM	1228:1232	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	8	62	theme	Field	1183:1187	arg1	Microscope					1216:1225	Field Emission Scanning Electron Microscope	1183:1225	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	6	63	theme	Chitosan	979:986	arg1	ratios					960:965	various ratios	952:965	various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT	952:1018	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	2	64	theme	therapeutic	335:345	arg1	effect					347:352	the therapeutic effect	331:352	the therapeutic effect in osteoarthritis treatments	331:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	9	65	theme	glucosamine	1471:1481	arg1	sulfate					1483:1489	glucosamine sulfate	1471:1489	glucosamine sulfate	1471:1489	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	8	66	theme	Scanning	1198:1205	arg1	FESEM					1228:1232	FESEM	1228:1232	FESEM	1228:1232	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	8	66	theme	Scanning	1198:1205	arg1	Microscope					1216:1225	Field Emission Scanning Electron Microscope	1183:1225	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	6	67	theme	Keratin	970:976	arg1	ratios					960:965	various ratios	952:965	various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT	952:1018	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	8	68	theme	Microscope	1216:1225	arg1	study					1235:1239	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study	1183:1239	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	7	69	theme	Molecular	1021:1029	arg1	analysis					1039:1046	Molecular docking analysis	1021:1046	Molecular docking analysis	1021:1046	Molecular docking analysis has been performed with (D-Glucosamine) and targeted proteins (PDB ID: 1HJV, 1ALU) to determine the binding affinity and interactions.					
37201514	11	70	theme	thermal	1748:1754	arg1	temperature					1770:1780	a high thermal decomposition temperature	1741:1780	a high thermal decomposition temperature of 420° C	1741:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	0	71	theme	osteoarthritis	99:112	arg1	delivery					119:126	osteoarthritis drug delivery	99:126	osteoarthritis drug delivery	99:126	Design and development of keratin/chitosan/glucosamine sulfate composite loaded MWCNT intended for osteoarthritis drug delivery.					
37201514	12	72	theme	maximum	1888:1894	arg1	500μg/ml					1911:1918	500μg/ml	1911:1918	500μg/ml	1911:1918	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	12	72	theme	maximum	1888:1894	arg1	concentration					1896:1908	the maximum concentration	1884:1908	the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite	1884:1953	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	6	73	theme	MWCNT	1014:1018	arg1	ratios					960:965	various ratios	952:965	various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT	952:1018	The nanocomposite was developed using various ratios of Keratin, Chitosan, Glucosamine sulfate, and MWCNT.					
37201514	12	74	theme	viability	1839:1847	arg1	%					1829:1829	83%	1827:1829	83% of cell viability	1827:1847	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	12	74	theme	viability	1839:1847	arg1	viability					1839:1847	cell viability	1834:1847	cell viability	1834:1847	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	11	75	theme	420°	1785:1788	arg1	C					1790:1790	420° C	1785:1790	420° C	1785:1790	Thermogravimetric (TGA) analysis revealed that the nanocomposite has a high thermal decomposition temperature of 420° C.					
37201514	13	76	theme	PDB	2072:2074	arg1	ID					2076:2077	PDB ID	2072:2077	PDB ID: 1HJV and 1ALU	2072:2092	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	8	77	theme	multi-walled	1326:1337	arg1	nanotubes					1346:1354	functionalized multi-walled carbon nanotubes	1311:1354	functionalized multi-walled carbon nanotubes	1311:1354	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	4	78	from	drug	573:576	arg1	view					542:545	this view	537:545	this view	537:545	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	13	79	theme	D-Glucosamine	2031:2043	arg1	affinity					2019:2026	the excellent binding affinity	1997:2026	the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU)	1997:2093	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	8	80	theme	nanotubes	1346:1354	arg1	surface					1300:1306	the surface	1296:1306	the surface of functionalized multi-walled carbon nanotubes	1296:1354	Field Emission Scanning Electron Microscope (FESEM) study showed that the composite (KRT/CS/GLS) incorporated on the surface of functionalized multi-walled carbon nanotubes effectively.					
37201514	2	81	theme	drug	398:401	arg1	design					403:408	the current drug design	386:408	the current drug design utilizing functional polymers	386:438	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	81	theme	drug	398:401	arg1	challenges					306:315	the most critical challenges	288:315	the most critical challenges for improving the therapeutic effect in osteoarthritis treatments	288:381	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	2	81	theme	drug	398:401	arg1	One					281:283	One	281:283	One	281:283	One of the most critical challenges for improving the therapeutic effect in osteoarthritis treatments is the current drug design utilizing functional polymers.					
37201514	5	82	theme	carbon	829:834	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	82	theme	carbon	829:834	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	82	theme	carbon	829:834	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	4	83	theme	glucosamine	548:558	arg1	sulfate					560:566	glucosamine sulfate	548:566	glucosamine sulfate	548:566	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	4	83	theme	glucosamine	548:558	arg1	drug					573:576	a drug	571:576	a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression	571:712	In this view, glucosamine sulfate is a drug used to manage osteoarthritis (OA) because of its potential therapeutic effects on cartilage and ability to inhibit disease progression.					
37201514	5	84	theme	composite	784:792	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	84	theme	composite	784:792	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	84	theme	composite	784:792	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	10	85	theme	amorphous	1655:1663	arg1	state					1665:1669	an amorphous state	1652:1669	an amorphous state	1652:1669	X-ray diffraction (XRD) analysis indicated that the nature of the composite in MWCNT transformed from a crystalline to an amorphous state.					
37201514	5	86	theme	functionalized	801:814	arg1	nanotubes					836:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes	745:844	a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT)	745:852	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	86	theme	functionalized	801:814	arg1	carrier					869:875	a potential carrier	857:875	a potential carrier for the treatment of osteoarthritis	857:911	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	5	86	theme	functionalized	801:814	arg1	MWCNT					847:851	MWCNT	847:851	MWCNT	847:851	This research aims to develop a Keratin/Chitosan/Glucosamine sulfate composite loaded functionalized multi-walled carbon nanotubes (MWCNT) as a potential carrier for the treatment of osteoarthritis.					
37201514	9	87	theme	Fourier	1369:1375	arg1	analysis					1416:1423	Fourier Transform Infrared spectroscopy (FTIR) analysis	1369:1423	Fourier Transform Infrared spectroscopy (FTIR) analysis	1369:1423	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	12	88	theme	assay	1801:1805	arg1	results					1807:1813	The MTT assay results	1793:1813	The MTT assay results	1793:1813	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	12	89	theme	RAW	1865:1867	arg1	cells					1875:1879	RAW 264.7 cells	1865:1879	RAW 264.7 cells	1865:1879	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	13	90	theme	binding	2011:2017	arg1	affinity					2019:2026	the excellent binding affinity	1997:2026	the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU)	1997:2093	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	3	91	theme	therapeutic	493:503	arg1	need					460:463	a need	458:463	a need to design	458:473	Indeed, there is a need to design and develop novel therapeutic drugs for positive outcomes.					
37201514	3	91	theme	therapeutic	493:503	arg1	drugs					505:509	novel therapeutic drugs	487:509	novel therapeutic drugs for positive outcomes	487:531	Indeed, there is a need to design and develop novel therapeutic drugs for positive outcomes.					
37201514	9	92	theme	Infrared	1387:1394	arg1	FTIR					1410:1413	FTIR	1410:1413	FTIR	1410:1413	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	9	92	theme	Infrared	1387:1394	arg1	spectroscopy					1396:1407	Infrared spectroscopy	1387:1407	Infrared spectroscopy (FTIR)	1387:1414	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
37201514	12	93	theme	cell	1834:1837	arg1	viability					1839:1847	cell viability	1834:1847	cell viability	1834:1847	The MTT assay results showed that 83% of cell viability has remained in RAW 264.7 cells at the maximum concentration (500μg/ml) of MWCNT-GLS/KRT/CS nanocomposite.					
37201514	13	94	theme	molecular	1962:1970	arg1	results					1980:1986	molecular docking results	1962:1986	molecular docking results	1962:1986	Also, molecular docking results revealed the excellent binding affinity of D-Glucosamine to each protein structure (PDB ID: 1HJV and 1ALU).					
37201514	9	95	theme	sulfate	1483:1489	arg1	presence					1436:1443	the presence	1432:1443	the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite	1432:1510	Fourier Transform Infrared spectroscopy (FTIR) analysis showed the presence of keratin, chitosan, and glucosamine sulfate in the nanocomposite and remained intact.					
36037922	7	0	theme	green	1073:1077	arg1	ability					1087:1093	malachite green removal ability	1063:1093	malachite green removal ability	1063:1093	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	5	1	theme	number	852:857	arg1	availability					832:843	availability	832:843	availability of the number of active sites	832:873	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	7	2	contain	had	1059:1061	arg2	ability					1087:1093	malachite green removal ability	1063:1093	malachite green removal ability	1063:1093	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	7	2	contain	had	1059:1061	arg1	bio-composite					1045:1057	the synthesized bio-composite	1029:1057	the synthesized bio-composite	1029:1057	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	1	3	theme	dye	313:315	arg1	removal					302:308	the removal	298:308	the removal of dye	298:315	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	7	4	theme	removal	1079:1085	arg1	ability					1087:1093	malachite green removal ability	1063:1093	malachite green removal ability	1063:1093	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	3	5	theme	green	477:481	arg1	solution					502:509	green malachite (MG) dye solution	477:509	green malachite (MG) dye solution	477:509	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	0	6	from	solutions	138:146	arg1	removal					94:100	removal	94:100	removal of green malachite dye from aqueous solutions	94:146	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	3	7	theme	dye	498:500	arg1	solution					502:509	green malachite (MG) dye solution	477:509	green malachite (MG) dye solution	477:509	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	1	8	theme	dextrin	225:231	arg1	nanoparticles					253:265	dextrin and zirconium oxide nanoparticles	225:265	dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites	225:293	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	7	9	theme	malachite	1063:1071	arg1	ability					1087:1093	malachite green removal ability	1063:1093	malachite green removal ability	1063:1093	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	5	10	theme	active	862:867	arg1	sites					869:873	active sites	862:873	active sites	862:873	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	7	11	theme	synthesized	1033:1043	arg1	bio-composite					1045:1057	the synthesized bio-composite	1029:1057	the synthesized bio-composite	1029:1057	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	3	12	theme	MG	494:495	arg1	solution					502:509	green malachite (MG) dye solution	477:509	green malachite (MG) dye solution	477:509	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	7	13	theme	aqueous	1100:1106	arg1	media					1108:1112	aqueous media	1100:1112	aqueous media	1100:1112	The results showed that the synthesized bio-composite had malachite green removal ability from aqueous media.					
36037922	4	14	theme	dosage	730:735	arg1	amount					710:715	the amount	706:715	the amount of adsorbent dosage	706:735	The data indicated that dye removal increased with increasing the amount of adsorbent dosage.					
36037922	4	14	theme	dosage	730:735	arg1	dosage					730:735	adsorbent dosage	720:735	adsorbent dosage	720:735	The data indicated that dye removal increased with increasing the amount of adsorbent dosage.					
36037922	2	15	theme	materials	373:381	arg1	characterization					337:352	characterization	337:352	characterization	337:352	Identification and characterization of the synthesized materials were examined using FTIR, XRD, SEM, and BET analyses.					
36037922	2	15	theme	materials	373:381	arg1	Identification					318:331	Identification	318:331	Identification	318:331	Identification and characterization of the synthesized materials were examined using FTIR, XRD, SEM, and BET analyses.					
36037922	6	16	theme	adsorption	929:938	arg1	process					940:946	the adsorption process	925:946	the adsorption process	925:946	The active adsorption sites are saturated during the adsorption process, by the molecules of the adsorbate and filled over time.					
36037922	3	17	theme	synthesized	519:529	arg1	nanocomposites					531:544	the synthesized nanocomposites	515:544	the synthesized nanocomposites	515:544	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	2	18	theme	synthesized	361:371	arg1	materials					373:381	the synthesized materials	357:381	the synthesized materials	357:381	Identification and characterization of the synthesized materials were examined using FTIR, XRD, SEM, and BET analyses.					
36037922	1	19	theme	zirconium	237:245	arg1	oxide					247:251	zirconium oxide	237:251	zirconium oxide	237:251	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	4	20	theme	adsorbent	720:728	arg1	dosage					730:735	adsorbent dosage	720:735	adsorbent dosage	720:735	The data indicated that dye removal increased with increasing the amount of adsorbent dosage.					
36037922	5	21	theme	availability	832:843	arg1	increase					820:827	the increase	816:827	the increase of availability of the number of active sites	816:873	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	0	22	theme	adsorbents	25:34	arg1	Fabrication					0:10	Fabrication	0:10	Fabrication of different adsorbents	0:34	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	1	23	theme	oxide	247:251	arg1	nanoparticles					253:265	dextrin and zirconium oxide nanoparticles	225:265	dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites	225:293	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	0	24	theme	green	105:109	arg1	dye					121:123	green malachite dye	105:123	green malachite dye	105:123	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	1	25	theme	graphene	164:171	arg1	oxide					173:177	graphene oxide	164:177	graphene oxide	164:177	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	0	26	theme	different	15:23	arg1	adsorbents					25:34	different adsorbents	15:34	different adsorbents	15:34	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	3	27	theme	solution	609:616	arg1	pH					618:619	solution pH	609:619	solution pH	609:619	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	5	28	theme	Increased	738:746	arg1	removal					752:758	Increased dye removal	738:758	Increased dye removal by increasing the adsorbent dosage	738:793	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	0	29	theme	dye	121:123	arg1	removal					94:100	removal	94:100	removal of green malachite dye from aqueous solutions	94:146	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	5	30	theme	dye	748:750	arg1	removal					752:758	Increased dye removal	738:758	Increased dye removal by increasing the adsorbent dosage	738:793	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	1	31	theme	adsorbent	270:278	arg1	nanocomposites					280:293	adsorbent nanocomposites	270:293	adsorbent nanocomposites	270:293	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	0	32	theme	malachite	111:119	arg1	dye					121:123	green malachite dye	105:123	green malachite dye	105:123	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	5	33	theme	adsorbent	778:786	arg1	dosage					788:793	the adsorbent dosage	774:793	the adsorbent dosage	774:793	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	1	34	theme	amine	183:187	arg1	graphene					189:196	amine graphene	183:196	amine graphene	183:196	In this study, graphene oxide and amine graphene were studied by binding to dextrin and zirconium oxide nanoparticles as adsorbent nanocomposites to the removal of dye.					
36037922	2	35	theme	BET	423:425	arg1	analyses					427:434	BET analyses	423:434	BET analyses	423:434	Identification and characterization of the synthesized materials were examined using FTIR, XRD, SEM, and BET analyses.					
36037922	0	36	theme	aqueous	130:136	arg1	solutions					138:146	aqueous solutions	130:146	aqueous solutions	130:146	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	4	37	theme	dye	668:670	arg1	removal					672:678	dye removal	668:678	dye removal	668:678	The data indicated that dye removal increased with increasing the amount of adsorbent dosage.					
36037922	0	38	theme	zirconium	45:53	arg1	oxide					55:59	zirconium oxide	45:59	zirconium oxide	45:59	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	6	39	theme	adsorption	887:896	arg1	sites					898:902	The active adsorption sites	876:902	The active adsorption sites	876:902	The active adsorption sites are saturated during the adsorption process, by the molecules of the adsorbate and filled over time.					
36037922	3	40	theme	adsorbent	626:634	arg1	dosage					636:641	adsorbent dosage	626:641	adsorbent dosage	626:641	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	5	41	theme	sites	869:873	arg1	number					852:857	the number	848:857	the number of active sites	848:873	Increased dye removal by increasing the adsorbent dosage can be attributed to the increase of availability of the number of active sites.					
36037922	6	42	theme	active	880:885	arg1	sites					898:902	The active adsorption sites	876:902	The active adsorption sites	876:902	The active adsorption sites are saturated during the adsorption process, by the molecules of the adsorbate and filled over time.					
36037922	3	43	theme	Adsorption	437:446	arg1	tests					448:452	Adsorption tests	437:452	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites	437:544	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	6	44	theme	adsorbate	973:981	arg1	molecules					956:964	the molecules	952:964	the molecules of the adsorbate	952:981	The active adsorption sites are saturated during the adsorption process, by the molecules of the adsorbate and filled over time.					
36037922	3	45	theme	contact	595:601	arg1	time					603:606	contact time	595:606	contact time	595:606	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
36037922	0	46	theme	graphene	62:69	arg1	oxide					71:75	graphene oxide	62:75	graphene oxide	62:75	Fabrication of different adsorbents based on zirconium oxide, graphene oxide, and dextrin for removal of green malachite dye from aqueous solutions.					
36037922	3	47	theme	malachite	483:491	arg1	solution					502:509	green malachite (MG) dye solution	477:509	green malachite (MG) dye solution	477:509	Adsorption tests between adsorbents and green malachite (MG) dye solution for the synthesized nanocomposites were performed by considering parameters such as contact time, solution pH, and adsorbent dosage.					
35686928	1	0	theme	tissue	279:284	arg1	applications					298:309	tissue engineering applications	279:309	tissue engineering applications	279:309	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	7	1	theme	injection-based	1717:1731	arg1	delivery					1733:1740	injection-based delivery	1717:1740	injection-based delivery	1717:1740	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	2	theme	fine	1667:1670	arg1	needle					1672:1677	a 27-gauge fine needle	1656:1677	a 27-gauge fine needle	1656:1677	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	6	3	theme	ultraviolet	1393:1403	arg1	irradiation					1410:1420	ultraviolet (UV) irradiation	1393:1420	ultraviolet (UV) irradiation	1393:1420	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	4	theme	mechanical	1469:1478	arg1	stress					1480:1485	mechanical stress	1469:1485	mechanical stress	1469:1485	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	1	5	theme	cells	193:197	arg1	Susceptibility					165:178	Susceptibility	165:178	Susceptibility of mammalian cells against harsh processing conditions	165:233	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	2	6	theme	microenvironment	343:358	arg1	modulation					320:329	modulation	320:329	modulation of the cell microenvironment	320:358	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	7	7	with	cells	1789:1793	arg1	rates					1815:1819	higher success rates	1800:1819	higher success rates	1800:1819	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	1	8	theme	harsh	207:211	arg1	conditions					224:233	harsh processing conditions	207:233	harsh processing conditions	207:233	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	6	9	theme	Human	1164:1168	arg1	stem					1182:1185	Human mesenchymal stem and neural progenitor cells	1164:1213	stem	1182:1185	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	7	10	theme	polyethylene	1620:1631	arg1	solution					1639:1646	viscous polyethylene oxide solution	1612:1646	viscous polyethylene oxide solution	1612:1646	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	0	11	theme	Composite	134:142	arg1	Microbeads					153:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	0	12	from	Encapsulation	58:70	arg1	Templated					84:92	Alginate Templated	75:92	Alginate Templated	75:92	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	0	12	from	Encapsulation	58:70	arg1	Microbeads					153:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	0	12	from	Encapsulation	58:70	arg1	Silk					112:115	Dual Crosslinked Silk	95:115	Dual Crosslinked Silk	95:115	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	6	13	theme	immune	1432:1437	arg1	recognition					1439:1449	immune recognition	1432:1449	immune recognition	1432:1449	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	4	14	theme	composite	811:819	arg1	microspheres					830:841	silk/gelatin composite hydrogel microspheres	798:841	silk/gelatin composite hydrogel microspheres	798:841	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	3	15	theme	structural	656:665	arg1	stability					667:675	low structural stability	652:675	low structural stability under physiological culture conditions and poor cell-matrix interactions	652:748	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	5	16	theme	mechanical	1090:1099	arg1	properties					1101:1110	improved mechanical properties	1081:1110	improved mechanical properties compared to ionically crosslinked Alg microspheres	1081:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	7	17	theme	progenitor	1576:1585	arg1	cells					1587:1591	encapsulated stem and progenitor cells	1554:1591	cells	1587:1591	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	18	theme	microspheres	830:841	arg1	fabrication					760:770	the fabrication	756:770	the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	756:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	6	19	theme	UV	1406:1407	arg1	irradiation					1410:1420	ultraviolet (UV) irradiation	1393:1420	ultraviolet (UV) irradiation	1393:1420	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	7	20	theme	stem	1567:1570	arg1	growth					1523:1528	growth	1523:1528	growth	1523:1528	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	20	theme	stem	1567:1570	arg1	differentiation					1535:1549	differentiation	1535:1549	differentiation	1535:1549	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	20	theme	stem	1567:1570	arg1	viability					1512:1520	viability	1512:1520	viability	1512:1520	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	21	theme	templated	779:787	arg1	silk					789:792	Alg templated silk	775:792	Alg templated silk	775:792	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	3	22	theme	culture	697:703	arg1	conditions					705:714	physiological culture conditions	683:714	physiological culture conditions	683:714	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	5	23	theme	exchange	1056:1063	arg1	conditions					1065:1074	ion exchange conditions	1052:1074	ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres	1052:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	5	24	with	conditions	1065:1074	arg1	properties					1101:1110	improved mechanical properties	1081:1110	improved mechanical properties compared to ionically crosslinked Alg microspheres	1081:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	0	25	theme	Alginate	75:82	arg1	Templated					84:92	Alginate Templated	75:92	Alginate Templated	75:92	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	6	26	theme	neural	1191:1196	arg1	cells					1209:1213	Human mesenchymal stem and neural progenitor cells	1164:1213	cells	1209:1213	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	4	27	theme	enzymatic	881:889	arg1	crosslinks					891:900	permanent or on-demand cleavable enzymatic crosslinks	848:900	permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	848:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	0	28	theme	Crosslinked	100:110	arg1	Silk					112:115	Dual Crosslinked Silk	95:115	Dual Crosslinked Silk	95:115	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	7	29	theme	encapsulated	1554:1565	arg1	stem					1567:1570	encapsulated stem and progenitor cells	1554:1591	stem	1567:1570	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	30	theme	permanent	848:856	arg1	crosslinks					891:900	permanent or on-demand cleavable enzymatic crosslinks	848:900	permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	848:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	2	31	theme	cells	505:509	arg1	isolation					475:483	physical isolation	466:483	physical isolation of the encapsulated cells	466:509	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	4	32	theme	on-demand	861:869	arg1	crosslinks					891:900	permanent or on-demand cleavable enzymatic crosslinks	848:900	permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	848:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	0	33	theme	Human	18:22	arg1	Progenitor					24:33	Human Progenitor and Stem Cells	18:48	Progenitor	24:33	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	7	34	theme	higher	1800:1805	arg1	rates					1815:1819	higher success rates	1800:1819	higher success rates	1800:1819	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	5	35	theme	Alg	1146:1148	arg1	microspheres					1150:1161	ionically crosslinked Alg microspheres	1124:1161	ionically crosslinked Alg microspheres	1124:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	6	36	theme	composite	1252:1260	arg1	beads					1262:1266	the composite beads	1248:1266	the composite beads	1248:1266	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	4	37	with	fabrication	760:770	arg1	crosslinks					891:900	permanent or on-demand cleavable enzymatic crosslinks	848:900	permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	848:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	3	38	theme	hydrogel	516:523	arg1	formulations					525:536	The hydrogel formulations	512:536	The hydrogel formulations used for cell microencapsulation	512:569	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	7	39	theme	cells	1789:1793	arg1	delivery					1733:1740	injection-based delivery	1717:1740	injection-based delivery	1717:1740	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	39	theme	cells	1789:1793	arg1	bioprinting					1764:1774	three-dimensional bioprinting	1746:1774	three-dimensional bioprinting	1746:1774	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	3	40	theme	cell-matrix	725:735	arg1	interactions					737:748	poor cell-matrix interactions	720:748	poor cell-matrix interactions	720:748	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	2	41	theme	cells	388:392	arg1	encapsulation					361:373	encapsulation	361:373	encapsulation of mammalian cells within hydrogel microbeads	361:419	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	0	42	theme	Cells	44:48	arg1	Cytoprotection					0:13	Cytoprotection	0:13	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.	0:163	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	3	43	theme	cell	547:550	arg1	microencapsulation					552:569	cell microencapsulation	547:569	cell microencapsulation	547:569	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	7	44	theme	three-dimensional	1746:1762	arg1	bioprinting					1764:1774	three-dimensional bioprinting	1746:1774	three-dimensional bioprinting	1746:1774	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	45	theme	centrifugation-based	934:953	arg1	processing					963:972	simple and cost-effective centrifugation-based droplet processing	908:972	simple and cost-effective centrifugation-based droplet processing	908:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	5	46	theme	structural	1025:1034	arg1	stability					1036:1044	structural stability	1025:1044	structural stability	1025:1044	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	1	47	theme	cell	254:257	arg1	transplantation					259:273	cell transplantation	254:273	cell transplantation	254:273	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	2	48	theme	hydrogel	401:408	arg1	microbeads					410:419	hydrogel microbeads	401:419	hydrogel microbeads	401:419	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	1	49	theme	engineering	286:296	arg1	applications					298:309	tissue engineering applications	279:309	tissue engineering applications	279:309	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	7	50	theme	potential	1691:1699	arg1	applications					1701:1712	potential applications	1691:1712	potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates	1691:1819	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	1	51	theme	mammalian	183:191	arg1	cells					193:197	mammalian cells	183:197	mammalian cells	183:197	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	7	52	theme	27-gauge	1658:1665	arg1	needle					1672:1677	a 27-gauge fine needle	1656:1677	a 27-gauge fine needle	1656:1677	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	6	53	theme	mesenchymal	1170:1180	arg1	stem					1182:1185	Human mesenchymal stem and neural progenitor cells	1164:1213	stem	1182:1185	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	54	theme	apoptotic	1372:1380	arg1	cytokines					1382:1390	apoptotic cytokines	1372:1390	apoptotic cytokines	1372:1390	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	0	55	theme	Silk-Gelatin	121:132	arg1	Microbeads					153:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	2	56	theme	cell	338:341	arg1	microenvironment					343:358	the cell microenvironment	334:358	the cell microenvironment	334:358	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	1	57	theme	processing	213:222	arg1	conditions					224:233	harsh processing conditions	207:233	harsh processing conditions	207:233	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	7	58	from	applications	1701:1712	arg1	delivery					1733:1740	injection-based delivery	1717:1740	injection-based delivery	1717:1740	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	58	from	applications	1701:1712	arg1	bioprinting					1764:1774	three-dimensional bioprinting	1746:1774	three-dimensional bioprinting	1746:1774	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	59	theme	oxide	1633:1637	arg1	solution					1639:1646	viscous polyethylene oxide solution	1612:1646	viscous polyethylene oxide solution	1612:1646	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	0	60	theme	Hydrogel	144:151	arg1	Microbeads					153:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Silk-Gelatin Composite Hydrogel Microbeads	121:162	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	5	61	theme	composite	996:1004	arg1	microbeads					1006:1015	The composite microbeads	992:1015	The composite microbeads	992:1015	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	3	62	link	crosslinked	606:616	arg1	Alg					628:630	Alg	628:630	Alg	628:630	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	3	62	link	crosslinked	606:616	arg1	alginate					618:625	ionically crosslinked alginate	596:625	ionically crosslinked alginate (Alg)	596:631	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	7	63	theme	viscous	1612:1618	arg1	solution					1639:1646	viscous polyethylene oxide solution	1612:1646	viscous polyethylene oxide solution	1612:1646	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	3	64	theme	low	652:654	arg1	stability					667:675	low structural stability	652:675	low structural stability under physiological culture conditions and poor cell-matrix interactions	652:748	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	5	65	theme	improved	1081:1088	arg1	properties					1101:1110	improved mechanical properties	1081:1110	improved mechanical properties compared to ionically crosslinked Alg microspheres	1081:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	4	66	theme	silk/gelatin	798:809	arg1	microspheres					830:841	silk/gelatin composite hydrogel microspheres	798:841	silk/gelatin composite hydrogel microspheres	798:841	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	1	67	from	use	247:249	arg1	transplantation					259:273	cell transplantation	254:273	cell transplantation	254:273	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	1	67	from	use	247:249	arg1	applications					298:309	tissue engineering applications	279:309	tissue engineering applications	279:309	Susceptibility of mammalian cells against harsh processing conditions limit their use in cell transplantation and tissue engineering applications.					
35686928	7	68	theme	cells	1587:1591	arg1	growth					1523:1528	growth	1523:1528	growth	1523:1528	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	68	theme	cells	1587:1591	arg1	differentiation					1535:1549	differentiation	1535:1549	differentiation	1535:1549	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	7	68	theme	cells	1587:1591	arg1	viability					1512:1520	viability	1512:1520	viability	1512:1520	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	69	theme	hydrogel	821:828	arg1	microspheres					830:841	silk/gelatin composite hydrogel microspheres	798:841	silk/gelatin composite hydrogel microspheres	798:841	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	3	70	theme	physiological	683:695	arg1	conditions					705:714	physiological culture conditions	683:714	physiological culture conditions	683:714	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	5	71	theme	ion	1052:1054	arg1	conditions					1065:1074	ion exchange conditions	1052:1074	ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres	1052:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	4	72	theme	Alg	775:777	arg1	silk					789:792	Alg templated silk	775:792	Alg templated silk	775:792	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	6	73	theme	progenitor	1198:1207	arg1	cells					1209:1213	Human mesenchymal stem and neural progenitor cells	1164:1213	cells	1209:1213	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	4	74	theme	silk	789:792	arg1	fabrication					760:770	the fabrication	756:770	the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	756:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	0	75	theme	Dual	95:98	arg1	Silk					112:115	Dual Crosslinked Silk	95:115	Dual Crosslinked Silk	95:115	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	4	76	theme	cleavable	871:879	arg1	crosslinks					891:900	permanent or on-demand cleavable enzymatic crosslinks	848:900	permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing	848:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	6	77	theme	environmental	1290:1302	arg1	anoikis					1423:1429	anoikis	1423:1429	anoikis	1423:1429	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	factors					1304:1310	environmental factors	1290:1310	environmental factors	1290:1310	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	stress					1480:1485	mechanical stress	1469:1485	mechanical stress	1469:1485	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	acidosis					1362:1369	extracellular acidosis	1348:1369	extracellular acidosis	1348:1369	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	exposure					1323:1330	exposure	1323:1330	exposure to polycations	1323:1345	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	recognition					1439:1449	immune recognition	1432:1449	immune recognition	1432:1449	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	cytokines					1382:1390	apoptotic cytokines	1372:1390	apoptotic cytokines	1372:1390	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	6	77	theme	environmental	1290:1302	arg1	irradiation					1410:1420	ultraviolet (UV) irradiation	1393:1420	ultraviolet (UV) irradiation	1393:1420	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	0	78	theme	Progenitor	24:33	arg1	Cytoprotection					0:13	Cytoprotection	0:13	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.	0:163	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	5	79	theme	crosslinked	1134:1144	arg1	microspheres					1150:1161	ionically crosslinked Alg microspheres	1124:1161	ionically crosslinked Alg microspheres	1124:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	7	80	from	extrusion	1599:1607	arg1	solution					1639:1646	viscous polyethylene oxide solution	1612:1646	viscous polyethylene oxide solution	1612:1646	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	2	81	theme	encapsulated	492:503	arg1	cells					505:509	the encapsulated cells	488:509	the encapsulated cells	488:509	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	0	82	theme	Stem	39:42	arg1	Cells					44:48	Human Progenitor and Stem Cells	18:48	Cells	44:48	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	7	83	theme	success	1807:1813	arg1	rates					1815:1819	higher success rates	1800:1819	higher success rates	1800:1819	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	3	84	theme	poor	720:723	arg1	interactions					737:748	poor cell-matrix interactions	720:748	poor cell-matrix interactions	720:748	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	4	85	theme	droplet	955:961	arg1	processing					963:972	simple and cost-effective centrifugation-based droplet processing	908:972	simple and cost-effective centrifugation-based droplet processing	908:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	2	86	theme	physical	466:473	arg1	isolation					475:483	physical isolation	466:483	physical isolation of the encapsulated cells	466:509	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	6	87	theme	extracellular	1348:1360	arg1	acidosis					1362:1369	extracellular acidosis	1348:1369	extracellular acidosis	1348:1369	Human mesenchymal stem and neural progenitor cells are successfully encapsulated in the composite beads and protected against environmental factors, including exposure to polycations, extracellular acidosis, apoptotic cytokines, ultraviolet (UV) irradiation, anoikis, immune recognition, and particularly mechanical stress.					
35686928	2	88	theme	mammalian	378:386	arg1	cells					388:392	mammalian cells	378:392	mammalian cells	378:392	Besides modulation of the cell microenvironment, encapsulation of mammalian cells within hydrogel microbeads attract attention for cytoprotection through physical isolation of the encapsulated cells.					
35686928	7	89	theme	mammalian	1779:1787	arg1	cells					1789:1793	mammalian cells	1779:1793	mammalian cells with higher success rates	1779:1819	The microbeads preserve viability, growth, and differentiation of encapsulated stem and progenitor cells after extrusion in viscous polyethylene oxide solution through a 27-gauge fine needle, suggesting potential applications in injection-based delivery and three-dimensional bioprinting of mammalian cells with higher success rates.					
35686928	4	90	theme	simple	908:913	arg1	processing					963:972	simple and cost-effective centrifugation-based droplet processing	908:972	simple and cost-effective centrifugation-based droplet processing	908:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	5	91	link	crosslinked	1134:1144	arg1	microspheres					1150:1161	ionically crosslinked Alg microspheres	1124:1161	ionically crosslinked Alg microspheres	1124:1161	The composite microbeads display structural stability under ion exchange conditions with improved mechanical properties compared to ionically crosslinked Alg microspheres.					
35686928	0	92	link	Crosslinked	100:110	arg1	Silk					112:115	Dual Crosslinked Silk	95:115	Dual Crosslinked Silk	95:115	Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.					
35686928	4	93	theme	cost-effective	919:932	arg1	processing					963:972	simple and cost-effective centrifugation-based droplet processing	908:972	simple and cost-effective centrifugation-based droplet processing	908:972	Here the fabrication of Alg templated silk and silk/gelatin composite hydrogel microspheres with permanent or on-demand cleavable enzymatic crosslinks using simple and cost-effective centrifugation-based droplet processing are demonstrated.					
35686928	3	94	theme	crosslinked	606:616	arg1	Alg					628:630	Alg	628:630	Alg	628:630	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35686928	3	94	theme	crosslinked	606:616	arg1	alginate					618:625	ionically crosslinked alginate	596:625	ionically crosslinked alginate (Alg)	596:631	The hydrogel formulations used for cell microencapsulation are largely dominated by ionically crosslinked alginate (Alg), which suffer from low structural stability under physiological culture conditions and poor cell-matrix interactions.					
35908715	9	0	theme	BB	1508:1509	arg1	impact					1498:1503	a stronger impact	1487:1503	a stronger impact of BB in the continental outflow	1487:1536	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	10	1	theme	photochemical	1763:1775	arg1	oxidation					1777:1785	a photochemical oxidation	1761:1785	a photochemical oxidation of BBOA	1761:1793	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	10	2	theme	Lev/K+	1571:1576	arg1	ratios					1578:1583	Lev/K+ ratios	1571:1583	Lev/K+ ratios in marine aerosols	1571:1602	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	2	3	theme	winter	625:630	arg1	cruise					632:637	a winter cruise	623:637	a winter cruise (6-24 December 2018)	623:658	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	3	theme	winter	625:630	arg1	December					645:652	December	645:652	December	645:652	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	12	4	theme	sugar-C	1967:1973	arg1	input					1958:1962	the aeolian input	1946:1962	the aeolian input of sugar-C and water-soluble organic carbon (WSOC)	1946:2013	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	1	5	theme	haze	182:185	arg1	pollution					187:195	The widespread haze pollution	167:195	The widespread haze pollution over South Asia	167:211	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	2	6	dep	alcohols	539:546	arg1	erythritol					569:578	erythritol	569:578	erythritol	569:578	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	6	dep	alcohols	539:546	arg1	inositol					585:592	inositol	585:592	inositol	585:592	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	6	dep	alcohols	539:546	arg1	mannitol					559:566	mannitol	559:566	mannitol	559:566	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	6	dep	alcohols	539:546	arg1	arabitol					549:556	arabitol	549:556	arabitol	549:556	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	6	dep	alcohols	539:546	arg1	alcohols					539:546	sugar alcohols	533:546	sugar alcohols (arabitol, mannitol, erythritol, and inositol)	533:593	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	5	7	link	BB-derived	1128:1137	arg1	OA					1139:1140	BB-derived OA	1128:1140	BB-derived OA	1128:1140	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	0	8	theme	molecular	99:107	arg1	distributions					109:121	molecular distributions	99:121	molecular distributions	99:121	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	8	9	from	burning	1294:1300	arg1	origin					1269:1274	their origin	1263:1274	their origin from crop-residue burning	1263:1300	0.27) ratios over the Arabian Sea with the source-emissions revealed their origin from crop-residue burning.					
35908715	11	10	theme	field-based	1801:1811	arg1	relationship					1813:1824	Such field-based relationship	1796:1824	Such field-based relationship of Lev with the meteorological parameters	1796:1866	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	13	11	theme	atmospheric	2112:2122	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	11	theme	atmospheric	2112:2122	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	11	12	theme	surface	1922:1928	arg1	Ocean					1930:1934	the surface Ocean	1918:1934	the surface Ocean	1918:1934	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	10	13	from	ratios	1578:1583	arg1	aerosols					1595:1602	marine aerosols	1588:1602	marine aerosols	1588:1602	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	4	14	theme	sugar	804:808	arg1	alcohols					810:817	sugar alcohols	804:817	sugar alcohols	804:817	Besides, levoglucosan strongly correlated with mannosan, galactosan, sugar alcohols and elemental carbon, emphasizing their BB-origin.					
35908715	0	15	theme	sugar	150:154	arg1	compounds					156:164	sugar compounds	150:164	sugar compounds	150:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	3	16	theme	Molecular	661:669	arg1	distributions					671:683	Molecular distributions	661:683	Molecular distributions	661:683	Molecular distributions revealed predominance of levoglucosan or sucrose.					
35908715	5	17	theme	TC	1050:1051	arg1	composition					1035:1045	stable carbon isotopic composition	1012:1045	stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C	1012:1079	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	10	18	theme	ambient	1657:1663	arg1	humidity					1674:1681	ambient relative humidity	1657:1681	ambient relative humidity	1657:1681	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	12	19	theme	Arabian	2074:2080	arg1	Sea					2082:2084	the Arabian Sea	2070:2084	the Arabian Sea	2070:2084	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	2	20	theme	Arabian	604:610	arg1	Sea					612:614	the Arabian Sea	600:614	the Arabian Sea	600:614	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	0	21	theme	winter	62:67	arg1	season					69:74	winter season	62:74	winter season	62:74	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	1	22	theme	due	311:313	arg1	Sea					307:309	the Arabian Sea	295:309	the Arabian Sea due to prevailing meteorology	295:339	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	2	23	dep	levoglucosan	422:433	arg1	Gal					453:455	Gal	453:455	Gal	453:455	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	23	dep	levoglucosan	422:433	arg1	mannosan					462:469	mannosan	462:469	mannosan	462:469	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	23	dep	levoglucosan	422:433	arg1	galactosan					441:450	galactosan	441:450	galactosan	441:450	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	23	dep	levoglucosan	422:433	arg1	Lev					436:438	Lev	436:438	Lev	436:438	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	23	dep	levoglucosan	422:433	arg1	Man					472:474	Man	472:474	levoglucosan: Lev, galactosan: Gal, and mannosan: Man	422:474	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	5	24	theme	carbon	1019:1024	arg1	composition					1035:1045	stable carbon isotopic composition	1012:1045	stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C	1012:1079	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	5	25	theme	Backward	870:877	arg1	trajectories					888:899	Backward air mass trajectories	870:899	Backward air mass trajectories	870:899	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	12	26	theme	riverine	2051:2058	arg1	supply					2060:2065	that riverine supply	2046:2065	that riverine supply to the Arabian Sea	2046:2084	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	8	27	theme	Arabian	1216:1222	arg1	Sea					1224:1226	the Arabian Sea	1212:1226	the Arabian Sea	1212:1226	0.27) ratios over the Arabian Sea with the source-emissions revealed their origin from crop-residue burning.					
35908715	5	28	theme	mass	883:886	arg1	trajectories					888:899	Backward air mass trajectories	870:899	Backward air mass trajectories	870:899	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	0	29	from	emissions	28:36	arg1	season					69:74	winter season	62:74	winter season	62:74	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	2	30	dep	anhydrosugars	407:419	arg1	levoglucosan					422:433	levoglucosan	422:433	levoglucosan: Lev, galactosan: Gal, and mannosan: Man	422:474	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	31	theme	alcohols	539:546	arg1	concentrations					360:373	the concentrations	356:373	the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol)	356:593	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	32	theme	derived	399:405	arg1	anhydrosugars					407:419	biomass burning (BB) derived anhydrosugars	378:419	biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man)	378:475	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	5	33	theme	satellite-based	920:934	arg1	counts					941:946	the satellite-based fire counts	916:946	the satellite-based fire counts	916:946	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	0	34	theme	biomass	12:18	arg1	emissions					28:36	the biomass burning emissions	8:36	the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds	8:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	1	35	theme	aerosols	276:283	arg1	abundance					255:263	the abundance	251:263	the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology	251:339	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	2	36	theme	burning	386:392	arg1	anhydrosugars					407:419	biomass burning (BB) derived anhydrosugars	378:419	biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man)	378:475	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	5	37	theme	fire	936:939	arg1	counts					941:946	the satellite-based fire counts	916:946	the satellite-based fire counts	916:946	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	11	38	from	impact	1900:1905	arg1	Ocean					1930:1934	the surface Ocean	1918:1934	the surface Ocean	1918:1934	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	1	39	theme	Arabian	299:305	arg1	Sea					307:309	the Arabian Sea	295:309	the Arabian Sea due to prevailing meteorology	295:339	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	0	40	dep	emissions	28:36	arg1	Implications					77:88	Implications	77:88	the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds	8:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	12	41	theme	water-soluble	1979:1991	arg1	WSOC					2009:2012	WSOC	2009:2012	WSOC	2009:2012	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	12	41	theme	water-soluble	1979:1991	arg1	carbon					2001:2006	water-soluble organic carbon	1979:2006	water-soluble organic carbon (WSOC)	1979:2013	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	13	42	theme	dissolved	2184:2192	arg1	compounds					2202:2210	dissolved organic compounds	2184:2210	dissolved organic compounds	2184:2210	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	11	43	theme	meteorological	1842:1855	arg1	parameters					1857:1866	the meteorological parameters	1838:1866	the meteorological parameters	1838:1866	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	13	44	theme	important	2155:2163	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	44	theme	important	2155:2163	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	12	45	theme	carbon	2001:2006	arg1	input					1958:1962	the aeolian input	1946:1962	the aeolian input of sugar-C and water-soluble organic carbon (WSOC)	1946:2013	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	5	46	theme	OA	1139:1140	arg1	impact					1118:1123	the impact	1114:1123	the impact of BB-derived OA	1114:1140	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	9	47	theme	stronger	1489:1496	arg1	impact					1498:1503	a stronger impact	1487:1503	a stronger impact of BB in the continental outflow	1487:1536	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	10	48	theme	Asian	1737:1741	arg1	outflow					1743:1749	the South Asian outflow	1727:1749	the South Asian outflow	1727:1749	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	10	49	theme	marine	1588:1593	arg1	aerosols					1595:1602	marine aerosols	1588:1602	marine aerosols	1588:1602	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	0	50	from	abundances	136:145	arg1	Implications					77:88	Implications	77:88	the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds	8:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	6	51	theme	Lev/Man	1159:1165	arg1	comparison					1145:1154	A comparison	1143:1154	A comparison of Lev/Man (av	1143:1169	A comparison of Lev/Man (av.					
35908715	13	52	theme	sugars	2142:2147	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	52	theme	sugars	2142:2147	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	9	53	theme	high	1310:1313	arg1	concentrations					1315:1328	Rather high concentrations	1303:1328	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific	1303:1468	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	2	54	dep	sugars	478:483	arg1	sugars					478:483	sugars	478:483	sugars (glucose, fructose, sucrose, and trehalose)	478:527	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	54	dep	sugars	478:483	arg1	sucrose					505:511	sucrose	505:511	sucrose	505:511	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	54	dep	sugars	478:483	arg1	trehalose					518:526	trehalose	518:526	trehalose	518:526	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	54	dep	sugars	478:483	arg1	fructose					495:502	fructose	495:502	fructose	495:502	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	54	dep	sugars	478:483	arg1	glucose					486:492	glucose	486:492	glucose	486:492	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	55	theme	sugar	533:537	arg1	erythritol					569:578	erythritol	569:578	erythritol	569:578	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	55	theme	sugar	533:537	arg1	inositol					585:592	inositol	585:592	inositol	585:592	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	55	theme	sugar	533:537	arg1	mannitol					559:566	mannitol	559:566	mannitol	559:566	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	55	theme	sugar	533:537	arg1	arabitol					549:556	arabitol	549:556	arabitol	549:556	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	55	theme	sugar	533:537	arg1	alcohols					539:546	sugar alcohols	533:546	sugar alcohols (arabitol, mannitol, erythritol, and inositol)	533:593	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	12	56	theme	aeolian	1950:1956	arg1	input					1958:1962	the aeolian input	1946:1962	the aeolian input of sugar-C and water-soluble organic carbon (WSOC)	1946:2013	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	1	57	theme	widespread	171:180	arg1	pollution					187:195	The widespread haze pollution	167:195	The widespread haze pollution over South Asia	167:211	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	9	58	theme	continental	1518:1528	arg1	outflow					1530:1536	the continental outflow	1514:1536	the continental outflow	1514:1536	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	59	theme	western	1448:1454	arg1	Pacific					1462:1468	the western North Pacific	1444:1468	the western North Pacific	1444:1468	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	13	60	theme	external	2165:2172	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	60	theme	external	2165:2172	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	2	61	theme	sugars	478:483	arg1	concentrations					360:373	the concentrations	356:373	the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol)	356:593	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	10	62	theme	BBOA	1790:1793	arg1	oxidation					1777:1785	a photochemical oxidation	1761:1785	a photochemical oxidation of BBOA	1761:1793	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	0	63	theme	relative	127:134	arg1	abundances					136:145	relative abundances	127:145	relative abundances	127:145	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	11	64	theme	Such	1796:1799	arg1	relationship					1813:1824	Such field-based relationship	1796:1824	Such field-based relationship of Lev with the meteorological parameters	1796:1866	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	9	65	theme	Lev	1333:1335	arg1	concentrations					1315:1328	Rather high concentrations	1303:1328	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific	1303:1468	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	66	theme	Arabian	1346:1352	arg1	Sea					1354:1356	the Arabian Sea	1342:1356	the Arabian Sea compared to those documented over the Bay of Bengal	1342:1408	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	67	from	impact	1498:1503	arg1	outflow					1530:1536	the continental outflow	1514:1536	the continental outflow	1514:1536	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	4	68	theme	elemental	823:831	arg1	carbon					833:838	elemental carbon	823:838	elemental carbon	823:838	Besides, levoglucosan strongly correlated with mannosan, galactosan, sugar alcohols and elemental carbon, emphasizing their BB-origin.					
35908715	5	69	theme	stable	1012:1017	arg1	composition					1035:1045	stable carbon isotopic composition	1012:1045	stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C	1012:1079	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	10	70	theme	apparent	1636:1643	arg1	increase					1645:1652	an apparent increase	1633:1652	an apparent increase in ambient relative humidity and temperature	1633:1697	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	0	71	theme	compounds	156:164	arg1	distributions					109:121	molecular distributions	99:121	molecular distributions	99:121	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	0	71	theme	compounds	156:164	arg1	abundances					136:145	relative abundances	127:145	relative abundances	127:145	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	5	72	theme	Indo-Gangetic	957:969	arg1	Plain					971:975	the Indo-Gangetic Plain	953:975	the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%)	953:1101	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	11	73	theme	Lev	1829:1831	arg1	relationship					1813:1824	Such field-based relationship	1796:1824	Such field-based relationship of Lev with the meteorological parameters	1796:1866	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	13	74	theme	compounds	2202:2210	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	74	theme	compounds	2202:2210	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	11	75	with	relationship	1813:1824	arg1	parameters					1857:1866	the meteorological parameters	1838:1866	the meteorological parameters	1838:1866	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	10	76	theme	relative	1665:1672	arg1	humidity					1674:1681	ambient relative humidity	1657:1681	ambient relative humidity	1657:1681	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	8	77	with	ratios	1200:1205	arg1	source-emissions					1237:1252	the source-emissions	1233:1252	the source-emissions	1233:1252	0.27) ratios over the Arabian Sea with the source-emissions revealed their origin from crop-residue burning.					
35908715	0	78	dep	distributions	109:121	arg1	the					95:97	the	95:97	the	95:97	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	1	79	theme	prevailing	318:327	arg1	meteorology					329:339	prevailing meteorology	318:339	prevailing meteorology	318:339	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	11	80	theme	BBOA	1910:1913	arg1	impact					1900:1905	the impact	1896:1905	the impact of BBOA on the surface Ocean	1896:1934	Such field-based relationship of Lev with the meteorological parameters can be useful for modelling the impact of BBOA on the surface Ocean.					
35908715	2	81	link	derived	399:405	arg1	anhydrosugars					407:419	biomass burning (BB) derived anhydrosugars	378:419	biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man)	378:475	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	3	82	theme	sucrose	726:732	arg1	predominance					694:705	predominance	694:705	predominance of levoglucosan or sucrose	694:732	Molecular distributions revealed predominance of levoglucosan or sucrose.					
35908715	9	83	theme	Bengal	1403:1408	arg1	Bay					1396:1398	the Bay	1392:1398	the Bay of Bengal	1392:1408	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	12	84	theme	supply	2060:2065	arg1	%					2032:2032	83 %	2029:2032	83 %	2029:2032	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	12	84	theme	supply	2060:2065	arg1	%					2041:2041	92 %	2038:2041	92 % of that riverine supply to the Arabian Sea	2038:2084	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	12	84	theme	supply	2060:2065	arg1	supply					2060:2065	that riverine supply	2046:2065	that riverine supply to the Arabian Sea	2046:2084	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	3	85	theme	levoglucosan	710:721	arg1	predominance					694:705	predominance	694:705	predominance of levoglucosan or sucrose	694:732	Molecular distributions revealed predominance of levoglucosan or sucrose.					
35908715	5	86	theme	isotopic	1026:1033	arg1	composition					1035:1045	stable carbon isotopic composition	1012:1045	stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C	1012:1079	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	9	87	theme	East	1411:1414	arg1	Sea					1422:1424	East China Sea	1411:1424	East China Sea	1411:1424	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	10	88	from	increase	1645:1652	arg1	temperature					1687:1697	temperature	1687:1697	temperature	1687:1697	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	10	88	from	increase	1645:1652	arg1	humidity					1674:1681	ambient relative humidity	1657:1681	ambient relative humidity	1657:1681	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	2	89	theme	anhydrosugars	407:419	arg1	concentrations					360:373	the concentrations	356:373	the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol)	356:593	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	0	90	theme	burning	20:26	arg1	emissions					28:36	the biomass burning emissions	8:36	the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds	8:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	1	91	theme	organic	268:274	arg1	aerosols					276:283	organic aerosols	268:283	organic aerosols (OA)	268:288	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	1	91	theme	organic	268:274	arg1	OA					286:287	OA	286:287	OA	286:287	The widespread haze pollution over South Asia typically occurs in winter, affecting the abundance of organic aerosols (OA) over the Arabian Sea due to prevailing meteorology.					
35908715	13	92	theme	surface	2219:2225	arg1	water					2227:2231	the surface water	2215:2231	the surface water	2215:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	5	93	theme	air	879:881	arg1	trajectories					888:899	Backward air mass trajectories	870:899	Backward air mass trajectories	870:899	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	10	94	theme	Arabian	1708:1714	arg1	Sea					1716:1718	the Arabian Sea	1704:1718	the Arabian Sea	1704:1718	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	13	95	theme	means	2106:2110	arg1	source					2174:2179	an important external source	2152:2179	an important external source of dissolved organic compounds to the surface water	2152:2231	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	13	95	theme	means	2106:2110	arg1	dry-deposition					2124:2137	This means atmospheric dry-deposition	2101:2137	This means atmospheric dry-deposition of sugars	2101:2147	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	9	96	theme	Japan	1434:1438	arg1	Pacific					1462:1468	the western North Pacific	1444:1468	the western North Pacific	1444:1468	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	96	theme	Japan	1434:1438	arg1	Sea					1427:1429	Sea	1427:1429	Sea of Japan	1427:1438	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	96	theme	Japan	1434:1438	arg1	Sea					1422:1424	East China Sea	1411:1424	East China Sea	1411:1424	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	96	theme	Japan	1434:1438	arg1	Sea					1354:1356	the Arabian Sea	1342:1356	the Arabian Sea compared to those documented over the Bay of Bengal	1342:1408	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	2	97	theme	biomass	378:384	arg1	burning					386:392	biomass burning	378:392	biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man)	378:475	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	2	97	theme	biomass	378:384	arg1	BB					395:396	BB	395:396	BB	395:396	We determined the concentrations of biomass burning (BB) derived anhydrosugars (levoglucosan: Lev, galactosan: Gal, and mannosan: Man), sugars (glucose, fructose, sucrose, and trehalose) and sugar alcohols (arabitol, mannitol, erythritol, and inositol) over the Arabian Sea during a winter cruise (6-24 December 2018).					
35908715	0	98	theme	Arabian	47:53	arg1	Sea					55:57	the Arabian Sea	43:57	the Arabian Sea	43:57	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	5	99	theme	levoglucosan-C	1066:1079	arg1	composition					1035:1045	stable carbon isotopic composition	1012:1045	stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C	1012:1079	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	13	100	theme	organic	2194:2200	arg1	compounds					2202:2210	dissolved organic compounds	2184:2210	dissolved organic compounds	2184:2210	This means atmospheric dry-deposition of sugars is an important external source of dissolved organic compounds to the surface water.					
35908715	9	101	theme	marine	1548:1553	arg1	basin					1555:1559	this marine basin	1543:1559	this marine basin	1543:1559	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	10	102	theme	South	1731:1735	arg1	outflow					1743:1749	the South Asian outflow	1727:1749	the South Asian outflow	1727:1749	Besides, Lev/K+ ratios in marine aerosols exponentially decreased with an apparent increase in ambient relative humidity and temperature over the Arabian Sea during the South Asian outflow, implying a photochemical oxidation of BBOA.					
35908715	5	103	theme	organic	1084:1090	arg1	%					1100:1100	%	1100:1100	%	1100:1100	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	5	103	theme	organic	1084:1090	arg1	carbon					1092:1097	organic carbon	1084:1097	organic carbon (%)	1084:1101	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	9	104	theme	North	1456:1460	arg1	Pacific					1462:1468	the western North Pacific	1444:1468	the western North Pacific	1444:1468	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	9	105	theme	China	1416:1420	arg1	Sea					1422:1424	East China Sea	1411:1424	East China Sea	1411:1424	Rather high concentrations of Lev over the Arabian Sea compared to those documented over the Bay of Bengal, East China Sea, Sea of Japan and the western North Pacific further suggests a stronger impact of BB in the continental outflow over this marine basin.					
35908715	8	106	theme	crop-residue	1281:1292	arg1	burning					1294:1300	crop-residue burning	1281:1300	crop-residue burning	1281:1300	0.27) ratios over the Arabian Sea with the source-emissions revealed their origin from crop-residue burning.					
35908715	5	107	theme	BB-derived	1128:1137	arg1	OA					1139:1140	BB-derived OA	1128:1140	BB-derived OA	1128:1140	Backward air mass trajectories intercepted by the satellite-based fire counts over the Indo-Gangetic Plain together with relationship between stable carbon isotopic composition of TC (δ13CTC) and levoglucosan-C to organic carbon (%), confirmed the impact of BB-derived OA.					
35908715	6	108	dep	comparison	1145:1154	arg1	av					1168:1169	av	1168:1169	A comparison of Lev/Man (av	1143:1169	A comparison of Lev/Man (av.					
35908715	7	109	dep	Lev/K+	1182:1187	arg1	av					1190:1191	av	1190:1191	av	1190:1191	16.2) and Lev/K+ (av.					
35908715	0	110	from	distributions	109:121	arg1	Implications					77:88	Implications	77:88	the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds	8:164	Tracing the biomass burning emissions over the Arabian Sea in winter season: Implications from the molecular distributions and relative abundances of sugar compounds.					
35908715	12	111	theme	organic	1993:1999	arg1	WSOC					2009:2012	WSOC	2009:2012	WSOC	2009:2012	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
35908715	12	111	theme	organic	1993:1999	arg1	carbon					2001:2006	water-soluble organic carbon	1979:2006	water-soluble organic carbon (WSOC)	1979:2013	Besides, the aeolian input of sugar-C and water-soluble organic carbon (WSOC) accounted for 83 % and 92 % of that riverine supply to the Arabian Sea, respectively.					
37196718	4	0	theme	high	703:706	arg1	strength					716:723	a high tensile strength	701:723	a high tensile strength of 9.14 kPa	701:735	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	3	1	theme	thermal	548:554	arg1	stability					556:564	thermal stability	548:564	thermal stability	548:564	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	1	2	theme	polyelectrolyte	273:287	arg1	hydrogel					299:306	a polyelectrolyte composite hydrogel	271:306	a polyelectrolyte composite hydrogel	271:306	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	0	3	theme	antibacterial	99:111	arg1	activity					113:120	synergistic antibacterial activity	87:120	synergistic antibacterial activity	87:120	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	1	4	theme	cationic	351:358	arg1	polysaccharide					360:373	a cationic polysaccharide	349:373	a cationic polysaccharide	349:373	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	4	theme	cationic	351:358	arg1	chitosan					334:341	chitosan	334:341	chitosan (CS)	334:346	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	6	5	theme	antibacterial	1050:1062	arg1	activity					1064:1071	synergistic antibacterial activity	1038:1071	synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli	1038:1124	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	4	6	theme	tensile	708:714	arg1	strength					716:723	a high tensile strength	701:723	a high tensile strength of 9.14 kPa	701:735	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	5	7	from	%	941:941	arg1	release					917:923	the release	913:923	the release from 60 % to 94 %	913:941	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	1	8	theme	composite	289:297	arg1	hydrogel					299:306	a polyelectrolyte composite hydrogel	271:306	a polyelectrolyte composite hydrogel	271:306	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	6	9	theme	synergistic	1038:1048	arg1	activity					1064:1071	synergistic antibacterial activity	1038:1071	synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli	1038:1124	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	7	10	theme	tissue	1269:1274	arg1	engineering					1276:1286	tissue engineering	1269:1286	tissue engineering	1269:1286	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	5	11	from	2.0	899:901	arg1	change					877:882	a change	875:882	a change from pH 7.4 to 2.0	875:901	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	3	12	theme	CS	575:576	arg1	ratio					585:589	an SG:CS weight ratio	569:589	an SG:CS weight ratio of 3:1	569:596	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	5	13	theme	60 	930:932	arg1	%					933:933	%	933:933	%	933:933	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	3	14	theme	weight	578:583	arg1	ratio					585:589	an SG:CS weight ratio	569:589	an SG:CS weight ratio of 3:1	569:596	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	4	15	theme	SG/CS	614:618	arg1	hydrogel					620:627	This optimized SG/CS hydrogel	599:627	This optimized SG/CS hydrogel	599:627	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	7	16	theme	hydrogel	1186:1193	arg1	potential					1168:1176	the potential	1164:1176	the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems	1164:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	7	17	theme	wound	1254:1258	arg1	healing					1260:1266	wound healing	1254:1266	wound healing	1254:1266	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	3	18	theme	SG	572:573	arg1	ratio					585:589	an SG:CS weight ratio	569:589	an SG:CS weight ratio of 3:1	569:596	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	1	19	theme	anionic	189:195	arg1	succinoglycan					129:141	succinoglycan	129:141	succinoglycan (SG) produced by Sinorhizobium meliloti	129:181	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	19	theme	anionic	189:195	arg1	polysaccharide					197:210	an anionic polysaccharide	186:210	an anionic polysaccharide having substituents such as succinate and pyruvate groups	186:268	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	5	20	theme	pH-controlled	807:819	arg1	pattern					834:840	a pH-controlled drug release pattern	805:840	a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %	805:941	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	4	21	theme	optimized	604:612	arg1	hydrogel					620:627	This optimized SG/CS hydrogel	599:627	This optimized SG/CS hydrogel	599:627	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	4	22	theme	84.65 	682:687	arg1	%					688:688	%	688:688	%	688:688	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	0	23	theme	pH-sensitive	2:13	arg1	delivery					20:27	A pH-sensitive drug delivery	0:27	A pH-sensitive drug delivery	0:27	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	5	24	theme	SG/CS	783:787	arg1	hydrogel					789:796	this SG/CS hydrogel	778:796	this SG/CS hydrogel	778:796	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	7	25	theme	hydrogel	1232:1239	arg1	material					1241:1248	a biocompatible and biodegradable hydrogel material	1198:1248	a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems	1198:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	3	26	theme	3:1	594:596	arg1	ratio					585:589	an SG:CS weight ratio	569:589	an SG:CS weight ratio of 3:1	569:596	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	7	27	theme	biocompatible	1200:1212	arg1	material					1241:1248	a biocompatible and biodegradable hydrogel material	1198:1248	a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems	1198:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	5	28	theme	release	826:832	arg1	pattern					834:840	a pH-controlled drug release pattern	805:840	a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %	805:941	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	5	29	dep	2.0	899:901	arg1	to					896:897	to	896:897	to	896:897	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	2	30	theme	SG/CS	406:410	arg1	hydrogels					412:420	polyelectrolyte SG/CS hydrogels	390:420	polyelectrolyte SG/CS hydrogels	390:420	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	2	31	theme	SD-A-SGT	476:483	arg1	method					486:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	5	32	dep	%	933:933	arg1	to					935:936	to	935:936	to	935:936	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	2	33	theme	transfer	466:473	arg1	method					486:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	0	34	theme	drug	15:18	arg1	delivery					20:27	A pH-sensitive drug delivery	0:27	A pH-sensitive drug delivery	0:27	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	5	35	theme	94 	938:940	arg1	%					933:933	%	933:933	%	933:933	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	2	36	theme	sol-gel	458:464	arg1	method					486:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	0	37	theme	biodegradable	35:47	arg1	hydrogels					72:80	biodegradable succinoglycan/chitosan hydrogels	35:80	biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity	35:120	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	7	38	theme	biodegradable	1218:1230	arg1	material					1241:1248	a biocompatible and biodegradable hydrogel material	1198:1248	a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems	1198:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	1	39	contain	having	212:217	arg1	succinoglycan					129:141	succinoglycan	129:141	succinoglycan (SG) produced by Sinorhizobium meliloti	129:181	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	39	contain	having	212:217	arg2	succinate					240:248	succinate	240:248	succinate	240:248	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	39	contain	having	212:217	arg2	substituents					219:230	substituents	219:230	substituents such as succinate and pyruvate groups	219:268	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	39	contain	having	212:217	arg1	polysaccharide					197:210	an anionic polysaccharide	186:210	an anionic polysaccharide having substituents such as succinate and pyruvate groups	186:268	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	1	39	contain	having	212:217	arg2	groups					263:268	pyruvate groups	254:268	pyruvate groups	254:268	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	6	40	theme	%	1019:1019	arg1	viability					1000:1008	a cell viability	993:1008	a cell viability of 97.57 %	993:1019	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	2	41	theme	acidified	448:456	arg1	method					486:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	4	42	theme	%	688:688	arg1	strain					690:695	84.65 % strain	682:695	84.65 % strain	682:695	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	6	43	theme	SG/CS	962:966	arg1	hydrogel					968:975	this SG/CS hydrogel	957:975	this SG/CS hydrogel	957:975	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	2	44	theme	semi-dissolving	432:446	arg1	method					486:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method	428:491	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	6	45	theme	cell	995:998	arg1	viability					1000:1008	a cell viability	993:1008	a cell viability of 97.57 %	993:1019	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	4	46	theme	9.14 kPa	728:735	arg1	strength					716:723	a high tensile strength	701:723	a high tensile strength of 9.14 kPa	701:735	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	4	46	theme	9.14 kPa	728:735	arg1	strain					690:695	84.65 % strain	682:695	84.65 % strain	682:695	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	0	47	theme	succinoglycan/chitosan	49:70	arg1	hydrogels					72:80	biodegradable succinoglycan/chitosan hydrogels	35:80	biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity	35:120	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	6	48	theme	%	1082:1082	arg1	activity					1064:1071	synergistic antibacterial activity	1038:1071	synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli	1038:1124	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	1	49	theme	Sinorhizobium	160:172	arg1	meliloti					174:181	Sinorhizobium meliloti	160:181	Sinorhizobium meliloti	160:181	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	7	50	theme	drug	1293:1296	arg1	systems					1306:1312	drug release systems	1293:1312	drug release systems	1293:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	3	51	theme	optimized	514:522	arg1	strength					535:542	mechanical strength	524:542	mechanical strength	524:542	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	6	52	theme	%	1094:1094	arg1	activity					1064:1071	synergistic antibacterial activity	1038:1071	synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli	1038:1124	In addition, this SG/CS hydrogel not only showed a cell viability of 97.57 %, but also showed synergistic antibacterial activity of 97.75 % and 96.76 % against S. aureus and E. coli, respectively.					
37196718	1	53	theme	pyruvate	254:261	arg1	groups					263:268	pyruvate groups	254:268	pyruvate groups	254:268	Since succinoglycan (SG) produced by Sinorhizobium meliloti is an anionic polysaccharide having substituents such as succinate and pyruvate groups, a polyelectrolyte composite hydrogel can be made together with chitosan (CS), a cationic polysaccharide.					
37196718	7	54	theme	release	1298:1304	arg1	systems					1306:1312	drug release systems	1293:1312	drug release systems	1293:1312	These results indicate the potential of this hydrogel as a biocompatible and biodegradable hydrogel material for wound healing, tissue engineering, and drug release systems.					
37196718	0	55	with	hydrogels	72:80	arg1	activity					113:120	synergistic antibacterial activity	87:120	synergistic antibacterial activity	87:120	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	3	56	theme	mechanical	524:533	arg1	strength					535:542	mechanical strength	524:542	mechanical strength	524:542	The hydrogel showed optimized mechanical strength and thermal stability at an SG:CS weight ratio of 3:1.					
37196718	0	57	theme	synergistic	87:97	arg1	activity					113:120	synergistic antibacterial activity	87:120	synergistic antibacterial activity	87:120	A pH-sensitive drug delivery using biodegradable succinoglycan/chitosan hydrogels with synergistic antibacterial activity.					
37196718	4	58	theme	497.67 kPa	668:677	arg1	stress					658:663	a high compressive stress	639:663	a high compressive stress of 497.67 kPa	639:677	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	2	59	theme	polyelectrolyte	390:404	arg1	hydrogels					412:420	polyelectrolyte SG/CS hydrogels	390:420	polyelectrolyte SG/CS hydrogels	390:420	We fabricated polyelectrolyte SG/CS hydrogels using the semi-dissolving acidified sol-gel transfer (SD-A-SGT) method.					
37196718	4	60	theme	compressive	646:656	arg1	stress					658:663	a high compressive stress	639:663	a high compressive stress of 497.67 kPa	639:677	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
37196718	5	61	theme	drug	821:824	arg1	pattern					834:840	a pH-controlled drug release pattern	805:840	a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %	805:941	Additionally, this SG/CS hydrogel showed a pH-controlled drug release pattern for 5-fluorouracil (5-FU), where a change from pH 7.4 to 2.0 increased the release from 60 % to 94 %.					
37196718	4	62	theme	high	641:644	arg1	stress					658:663	a high compressive stress	639:663	a high compressive stress of 497.67 kPa	639:677	This optimized SG/CS hydrogel exhibited a high compressive stress of 497.67 kPa at 84.65 % strain and a high tensile strength of 9.14 kPa when stretched to 43.73 %.					
35628220	1	0	theme	simple	174:179	arg1	method					224:229	a simple, fast, and cost-effective co-precipitation method	172:229	a simple, fast, and cost-effective co-precipitation method with cornstarch	172:245	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	6	1	theme	auxiliary	1088:1096	arg1	fragment					1098:1105	an auxiliary fragment	1085:1105	an auxiliary fragment	1085:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	0	2	theme	Proteins	89:96	arg1	Purification					61:72	Affinity Purification	52:72	Affinity Purification of Recombinant Proteins	52:96	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	5	3	theme	determined	712:721	arg1	characteristics					732:746	The determined magnetic characteristics	708:746	The determined magnetic characteristics	708:746	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	8	4	theme	nanoparticles	1501:1513	arg1	milligram					1454:1462	milligram	1454:1462	milligram of starch-coated magnetic iron oxide nanoparticles	1454:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	6	5	theme	several	944:950	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	5	theme	several	944:950	arg1	survivin					994:1001	survivin	994:1001	survivin	994:1001	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	5	theme	several	944:950	arg1	I					991:991	cardiac troponin I	974:991	cardiac troponin I	974:991	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	5	theme	several	944:950	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	7	6	theme	magnetic	1261:1268	arg1	nanoparticles					1270:1282	magnetic nanoparticles	1261:1282	magnetic nanoparticles	1261:1282	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	8	7	theme	iron	1490:1493	arg1	nanoparticles					1501:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	5	8	theme	magnetic	723:730	arg1	characteristics					732:746	The determined magnetic characteristics	708:746	The determined magnetic characteristics	708:746	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	2	9	theme	synthesized	322:332	arg1	material					334:341	the synthesized material	318:341	the synthesized material	318:341	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	4	10	theme	composite	643:651	arg1	particles					653:661	the prepared composite particles	630:661	the prepared composite particles	630:661	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	1	11	dep	simple	174:179	arg1	co-precipitation					207:222	co-precipitation	207:222	co-precipitation	207:222	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	7	12	theme	maltose	1304:1310	arg1	solution					1312:1319	the maltose solution	1300:1319	the maltose solution	1300:1319	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	4	13	theme	prepared	634:641	arg1	particles					653:661	the prepared composite particles	630:661	the prepared composite particles	630:661	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	5	14	theme	magnetic	806:813	arg1	separation					815:824	magnetic separation	806:824	magnetic separation	806:824	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	6	15	theme	troponin	982:989	arg1	I					991:991	cardiac troponin I	974:991	cardiac troponin I	974:991	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	15	theme	troponin	982:989	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	16	theme	purification	1362:1373	arg1	reusability					1521:1531	reusability	1521:1531	reusability of the obtained material	1521:1556	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	16	theme	purification	1362:1373	arg1	efficiency					1336:1345	The excellent efficiency	1322:1345	The excellent efficiency of column-free purification	1322:1373	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	16	theme	purification	1362:1373	arg1	capacity					1389:1396	high binding capacity	1376:1396	high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles)	1376:1514	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	1	17	theme	fast	182:185	arg1	method					224:229	a simple, fast, and cost-effective co-precipitation method	172:229	a simple, fast, and cost-effective co-precipitation method with cornstarch	172:245	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	6	18	theme	cardiac	974:980	arg1	I					991:991	cardiac troponin I	974:991	cardiac troponin I	974:991	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	18	theme	cardiac	974:980	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	2	19	theme	magnetic	290:297	arg1	characteristics					299:313	The structural and magnetic characteristics	271:313	The structural and magnetic characteristics of the synthesized material	271:341	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	2	20	theme	vibrating	426:434	arg1	magnetometry					443:454	vibrating sample magnetometry	426:454	vibrating sample magnetometry	426:454	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	0	21	theme	Magnetic	14:21	arg1	Oxide					28:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	7	22	theme	specific	1150:1157	arg1	binding					1159:1165	the highly specific binding	1139:1165	the highly specific binding of this fragment to the starch shell	1139:1202	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	1	23	theme	Starch-coated	99:111	arg1	nanoparticles					133:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	1	23	theme	Starch-coated	99:111	arg1	agent					264:268	a stabilizing agent	250:268	a stabilizing agent	250:268	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	0	24	theme	Starch-Coated	0:12	arg1	Oxide					28:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	6	25	theme	maltose-binding	1058:1072	arg1	protein					1074:1080	the maltose-binding protein	1054:1080	the maltose-binding protein as an auxiliary fragment	1054:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	26	theme	material	1549:1556	arg1	reusability					1521:1531	reusability	1521:1531	reusability of the obtained material	1521:1556	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	26	theme	material	1549:1556	arg1	efficiency					1336:1345	The excellent efficiency	1322:1345	The excellent efficiency of column-free purification	1322:1373	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	26	theme	material	1549:1556	arg1	capacity					1389:1396	high binding capacity	1376:1396	high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles)	1376:1514	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	1	27	theme	magnetic	113:120	arg1	nanoparticles					133:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	1	27	theme	magnetic	113:120	arg1	agent					264:268	a stabilizing agent	250:268	a stabilizing agent	250:268	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	8	28	theme	excellent	1326:1334	arg1	efficiency					1336:1345	The excellent efficiency	1322:1345	The excellent efficiency of column-free purification	1322:1373	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	1	29	theme	cost-effective	192:205	arg1	method					224:229	a simple, fast, and cost-effective co-precipitation method	172:229	a simple, fast, and cost-effective co-precipitation method with cornstarch	172:245	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	7	30	theme	fusion	1216:1221	arg1	protein					1223:1229	the target fusion protein	1205:1229	the target fusion protein	1205:1229	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	6	31	theme	oxide	855:859	arg1	nanoparticles					861:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	31	theme	oxide	855:859	arg1	affinity					898:905	an affinity	895:905	an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	895:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	2	32	theme	material	334:341	arg1	characteristics					299:313	The structural and magnetic characteristics	271:313	The structural and magnetic characteristics of the synthesized material	271:341	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	4	33	theme	magnetic	685:692	arg1	measurements					694:705	magnetic measurements	685:705	magnetic measurements	685:705	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	0	34	theme	Iron	23:26	arg1	Oxide					28:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide	0:32	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	5	35	theme	good	780:783	arg1	candidate					785:793	a good candidate	778:793	a good candidate for use in magnetic separation	778:824	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	6	36	theme	proteins	964:971	arg1	purification					928:939	one-step purification	919:939	one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	919:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	1	37	theme	oxide	127:131	arg1	nanoparticles					133:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	1	37	theme	oxide	127:131	arg1	agent					264:268	a stabilizing agent	250:268	a stabilizing agent	250:268	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	7	38	theme	target	1209:1214	arg1	protein					1223:1229	the target fusion protein	1205:1229	the target fusion protein	1205:1229	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	3	39	theme	starch	518:523	arg1	shell					525:529	a starch shell	516:529	a starch shell	516:529	The nature of bonds between ferrihydrite nanoparticles and a starch shell has been examined by Fourier transform infrared spectroscopy.					
35628220	4	40	from	data	597:600	arg1	response					618:625	the magnetic response	605:625	the magnetic response of the prepared composite particles	605:661	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	4	41	theme	magnetic	609:616	arg1	response					618:625	the magnetic response	605:625	the magnetic response of the prepared composite particles	605:661	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	6	42	theme	recombinant	952:962	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	42	theme	recombinant	952:962	arg1	survivin					994:1001	survivin	994:1001	survivin	994:1001	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	42	theme	recombinant	952:962	arg1	I					991:991	cardiac troponin I	974:991	cardiac troponin I	974:991	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	42	theme	recombinant	952:962	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	43	dep	sorbent	1405:1411	arg1	µg					1422:1423	100-500 µg	1414:1423	100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles	1414:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	3	44	theme	bonds	471:475	arg1	nature					461:466	The nature	457:466	The nature of bonds between ferrihydrite nanoparticles and a starch shell	457:529	The nature of bonds between ferrihydrite nanoparticles and a starch shell has been examined by Fourier transform infrared spectroscopy.					
35628220	8	45	theme	column-free	1350:1360	arg1	purification					1362:1373	column-free purification	1350:1373	column-free purification	1350:1373	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	2	46	theme	sample	436:441	arg1	magnetometry					443:454	vibrating sample magnetometry	426:454	vibrating sample magnetometry	426:454	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	1	47	with	method	224:229	arg1	cornstarch					236:245	cornstarch	236:245	cornstarch	236:245	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	5	48	from	use	799:801	arg1	separation					815:824	magnetic separation	806:824	magnetic separation	806:824	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	6	49	theme	iron	850:853	arg1	nanoparticles					861:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	49	theme	iron	850:853	arg1	affinity					898:905	an affinity	895:905	an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	895:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	7	50	theme	starch	1191:1196	arg1	shell					1198:1202	the starch shell	1187:1202	the starch shell	1187:1202	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	6	51	theme	activity	1028:1035	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	51	theme	activity	1028:1035	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	52	theme	recombinant	1430:1440	arg1	protein					1442:1448	a recombinant protein	1428:1448	a recombinant protein	1428:1448	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	53	theme	magnetic	1481:1488	arg1	nanoparticles					1501:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	6	54	theme	magnetic	841:848	arg1	nanoparticles					861:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	54	theme	magnetic	841:848	arg1	affinity					898:905	an affinity	895:905	an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	895:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	2	55	theme	electron	377:384	arg1	microscopy					386:395	transmission electron microscopy	364:395	transmission electron microscopy	364:395	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	0	56	theme	Affinity	52:59	arg1	Purification					61:72	Affinity Purification	52:72	Affinity Purification of Recombinant Proteins	52:96	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	6	57	theme	inhibitory	1017:1026	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	57	theme	inhibitory	1017:1026	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	58	theme	obtained	1540:1547	arg1	material					1549:1556	the obtained material	1536:1556	the obtained material	1536:1556	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	3	59	dep	Fourier	552:558	arg1	transform					560:568	transform	560:568	transform infrared spectroscopy	560:590	The nature of bonds between ferrihydrite nanoparticles and a starch shell has been examined by Fourier transform infrared spectroscopy.					
35628220	6	60	theme	Starch-coated	827:839	arg1	nanoparticles					861:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	60	theme	Starch-coated	827:839	arg1	affinity					898:905	an affinity	895:905	an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	895:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	2	61	theme	transmission	364:375	arg1	microscopy					386:395	transmission electron microscopy	364:395	transmission electron microscopy	364:395	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	6	62	theme	melanoma	1008:1015	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	62	theme	melanoma	1008:1015	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	5	63	theme	synthesized	757:767	arg1	material					769:776	the synthesized material	753:776	the synthesized material	753:776	The determined magnetic characteristics make the synthesized material a good candidate for use in magnetic separation.					
35628220	6	64	theme	one-step	919:926	arg1	purification					928:939	one-step purification	919:939	one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	919:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	65	theme	oxide	1495:1499	arg1	nanoparticles					1501:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	66	theme	protein	1442:1448	arg1	µg					1422:1423	100-500 µg	1414:1423	100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles	1414:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	67	theme	binding	1381:1387	arg1	capacity					1389:1396	high binding capacity	1376:1396	high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles)	1376:1514	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	1	68	theme	iron	122:125	arg1	nanoparticles					133:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	1	68	theme	iron	122:125	arg1	agent					264:268	a stabilizing agent	250:268	a stabilizing agent	250:268	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	2	69	theme	structural	275:284	arg1	characteristics					299:313	The structural and magnetic characteristics	271:313	The structural and magnetic characteristics of the synthesized material	271:341	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35628220	7	70	theme	fragment	1175:1182	arg1	binding					1159:1165	the highly specific binding	1139:1165	the highly specific binding of this fragment to the starch shell	1139:1202	It has been shown that, due to the highly specific binding of this fragment to the starch shell, the target fusion protein is selectively immobilized on magnetic nanoparticles and eluted with the maltose solution.					
35628220	8	71	theme	high	1376:1379	arg1	capacity					1389:1396	high binding capacity	1376:1396	high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles)	1376:1514	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	72	theme	sorbent	1405:1411	arg1	reusability					1521:1531	reusability	1521:1531	reusability of the obtained material	1521:1556	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	72	theme	sorbent	1405:1411	arg1	efficiency					1336:1345	The excellent efficiency	1322:1345	The excellent efficiency of column-free purification	1322:1373	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	8	72	theme	sorbent	1405:1411	arg1	capacity					1389:1396	high binding capacity	1376:1396	high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles)	1376:1514	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	4	73	theme	particles	653:661	arg1	response					618:625	the magnetic response	605:625	the magnetic response of the prepared composite particles	605:661	The data on the magnetic response of the prepared composite particles have been obtained by magnetic measurements.					
35628220	0	74	theme	Recombinant	77:87	arg1	Proteins					89:96	Recombinant Proteins	77:96	Recombinant Proteins	77:96	Starch-Coated Magnetic Iron Oxide Nanoparticles for Affinity Purification of Recombinant Proteins.					
35628220	6	75	theme	sorbent	907:913	arg1	nanoparticles					861:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles	827:873	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	75	theme	sorbent	907:913	arg1	affinity					898:905	an affinity	895:905	an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	895:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	8	76	theme	starch-coated	1467:1479	arg1	nanoparticles					1501:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	starch-coated magnetic iron oxide nanoparticles	1467:1513	The excellent efficiency of column-free purification, high binding capacity of the sorbent (100-500 µg of a recombinant protein per milligram of starch-coated magnetic iron oxide nanoparticles), and reusability of the obtained material have been demonstrated.					
35628220	3	77	theme	ferrihydrite	485:496	arg1	nanoparticles					498:510	ferrihydrite nanoparticles	485:510	ferrihydrite nanoparticles	485:510	The nature of bonds between ferrihydrite nanoparticles and a starch shell has been examined by Fourier transform infrared spectroscopy.					
35628220	1	78	theme	stabilizing	252:262	arg1	nanoparticles					133:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles	99:145	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	1	78	theme	stabilizing	252:262	arg1	agent					264:268	a stabilizing agent	250:268	a stabilizing agent	250:268	Starch-coated magnetic iron oxide nanoparticles have been synthesized by a simple, fast, and cost-effective co-precipitation method with cornstarch as a stabilizing agent.					
35628220	3	79	dep	transform	560:568	arg1	infrared					570:577	infrared	570:577	transform infrared spectroscopy	560:590	The nature of bonds between ferrihydrite nanoparticles and a starch shell has been examined by Fourier transform infrared spectroscopy.					
35628220	6	80	dep	proteins	964:971	arg1	protein					1037:1043	melanoma inhibitory activity protein	1008:1043	melanoma inhibitory activity protein	1008:1043	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	80	dep	proteins	964:971	arg1	survivin					994:1001	survivin	994:1001	survivin	994:1001	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	80	dep	proteins	964:971	arg1	I					991:991	cardiac troponin I	974:991	cardiac troponin I	974:991	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	6	80	dep	proteins	964:971	arg1	proteins					964:971	several recombinant proteins	944:971	several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment	944:1105	Starch-coated magnetic iron oxide nanoparticles have been tested as an affinity sorbent for one-step purification of several recombinant proteins (cardiac troponin I, survivin, and melanoma inhibitory activity protein) bearing the maltose-binding protein as an auxiliary fragment.					
35628220	2	81	theme	Mössbauer	398:406	arg1	spectroscopy					408:419	Mössbauer spectroscopy	398:419	Mössbauer spectroscopy	398:419	The structural and magnetic characteristics of the synthesized material have been studied by transmission electron microscopy, Mössbauer spectroscopy, and vibrating sample magnetometry.					
35513693	4	0	theme	fiber	1027:1031	arg1	structure					1033:1041	the fiber structure	1023:1041	the fiber structure	1023:1041	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	6	1	theme	topical	1432:1438	arg1	therapy					1467:1473	topical antimicrobial photodynamic therapy	1432:1473	topical antimicrobial photodynamic therapy	1432:1473	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	3	2	theme	phthalocyanine	763:776	arg1	derivative					778:787	silicon(IV)phthalocyanine derivative	752:787	silicon(IV)phthalocyanine derivative	752:787	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	5	3	theme	polymer	1188:1194	arg1	mixture					1196:1202	the polymer mixture	1184:1202	the polymer mixture	1184:1202	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	6	4	theme	resulting	1372:1380	arg1	materials					1382:1390	the resulting materials	1368:1390	the resulting materials	1368:1390	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	6	5	theme	valuable	1400:1407	arg1	opportunities					1409:1421	valuable opportunities	1400:1421	valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation	1400:1515	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	3	6	theme	present	545:551	arg1	study					553:557	the present study	541:557	the present study	541:557	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	1	7	theme	major	290:294	arg1	endeavor					296:303	a major endeavor	288:303	a major endeavor that requires development of new and innovative materials	288:361	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	1	7	theme	major	290:294	arg1	effort					233:238	The ongoing effort	221:238	The ongoing effort to eradicate pathogenic bacteria and viruses	221:283	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	0	8	from	Influence	0:8	arg1	activity					97:104	photoinduced antimicrobial activity	70:104	photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	70:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	4	9	theme	cross-linking	916:928	arg1	process					930:936	A straightforward cross-linking process	898:936	A straightforward cross-linking process	898:936	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	5	10	theme	material	1297:1304	arg1	activity					1281:1288	the activity	1277:1288	the activity of the material	1277:1304	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	3	11	theme	carrier	830:836	arg1	polymer					838:844	carrier polymer	830:844	carrier polymer	830:844	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	0	12	theme	PVA-	109:112	arg1	nanomaterials					149:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	4	13	theme	straightforward	900:914	arg1	process					930:936	A straightforward cross-linking process	898:936	A straightforward cross-linking process	898:936	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	3	14	theme	antibacterial	580:592	arg1	activities					608:617	the antibacterial and antiviral activities	576:617	the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	576:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	4	15	theme	structure	1033:1041	arg1	distribution					1007:1018	an almost uniform distribution	989:1018	an almost uniform distribution of the fiber structure	989:1041	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	3	16	theme	polymer	838:844	arg1	role					818:821	the role	814:821	the role of the carrier polymer and photosensitizers concentration on its efficacy	814:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	0	17	theme	electrospun	137:147	arg1	nanomaterials					149:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	4	18	with	material	975:982	arg1	distribution					1007:1018	an almost uniform distribution	989:1018	an almost uniform distribution of the fiber structure	989:1041	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	6	19	theme	antimicrobial	1344:1356	arg1	activity					1358:1365	their visible light-triggered antimicrobial activity	1314:1365	their visible light-triggered antimicrobial activity	1314:1365	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	5	20	theme	photosensitizer	1237:1251	arg1	concentration					1253:1265	the photosensitizer concentration	1233:1265	the photosensitizer concentration	1233:1265	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	0	21	theme	PVA-chitosan-based	118:135	arg1	nanomaterials					149:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	PVA- and PVA-chitosan-based electrospun nanomaterials	109:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	2	22	theme	principles	514:523	arg1	understanding					481:493	a broad understanding	473:493	a broad understanding of chemical design principles	473:523	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	6	23	theme	remediation	1505:1515	arg1	therapy					1467:1473	topical antimicrobial photodynamic therapy	1432:1473	topical antimicrobial photodynamic therapy	1432:1473	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	6	23	theme	remediation	1505:1515	arg1	area					1483:1486	the area	1479:1486	the area of environmental remediation	1479:1515	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	4	24	theme	uniform	999:1005	arg1	distribution					1007:1018	an almost uniform distribution	989:1018	an almost uniform distribution of the fiber structure	989:1041	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	4	25	theme	scanning	1059:1066	arg1	microscopy					1077:1086	scanning electron microscopy	1059:1086	scanning electron microscopy	1059:1086	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	3	26	theme	silicon	752:758	arg1	derivative					778:787	silicon(IV)phthalocyanine derivative	752:787	silicon(IV)phthalocyanine derivative	752:787	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	6	27	theme	photodynamic	1454:1465	arg1	therapy					1467:1473	topical antimicrobial photodynamic therapy	1432:1473	topical antimicrobial photodynamic therapy	1432:1473	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	3	28	from	role	818:821	arg1	efficacy					888:895	its efficacy	884:895	its efficacy	884:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	2	29	theme	attractive	429:438	arg1	area					440:443	an emerging and attractive area	413:443	an emerging and attractive area of research	413:455	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	2	30	theme	broad	475:479	arg1	understanding					481:493	a broad understanding	473:493	a broad understanding of chemical design principles	473:523	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	5	31	theme	chitosan	1172:1179	arg1	amount					1162:1167	the amount	1158:1167	the amount of chitosan in the polymer mixture	1158:1202	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	5	31	theme	chitosan	1172:1179	arg1	chitosan					1172:1179	chitosan	1172:1179	chitosan	1172:1179	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	1	32	theme	ongoing	225:231	arg1	endeavor					296:303	a major endeavor	288:303	a major endeavor that requires development of new and innovative materials	288:361	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	1	32	theme	ongoing	225:231	arg1	effort					233:238	The ongoing effort	221:238	The ongoing effort to eradicate pathogenic bacteria and viruses	221:283	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	0	33	theme	concentration	29:41	arg1	Influence					0:8	Influence	0:8	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	0:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	3	34	theme	-chitosan	713:721	arg1	mixture					723:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture	671:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	671:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	0	35	theme	photosensitizer	13:27	arg1	concentration					29:41	photosensitizer concentration	13:41	photosensitizer concentration	13:41	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	0	36	theme	nanomaterials	149:161	arg1	activity					97:104	photoinduced antimicrobial activity	70:104	photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	70:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	4	37	theme	water-stable	962:973	arg1	material					975:982	a water-stable material	960:982	a water-stable material with an almost uniform distribution of the fiber structure	960:1041	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	3	38	theme	antiviral	598:606	arg1	activities					608:617	the antibacterial and antiviral activities	576:617	the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	576:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	0	39	theme	polymer	47:53	arg1	composition					55:65	polymer composition	47:65	polymer composition	47:65	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	1	40	theme	new	334:336	arg1	materials					353:361	new and innovative materials	334:361	new and innovative materials	334:361	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	0	41	theme	tailor-made	181:191	arg1	phthalocyanine					205:218	tailor-made silicon(IV) phthalocyanine	181:218	tailor-made silicon(IV) phthalocyanine	181:218	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	5	42	theme	antimicrobial	1108:1120	arg1	studies					1122:1128	the antimicrobial studies	1104:1128	the antimicrobial studies	1104:1128	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	3	43	theme	nanofibrous	637:647	arg1	membranes					649:657	five different nanofibrous membranes	622:657	five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	622:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	2	44	theme	design	507:512	arg1	principles					514:523	chemical design principles	498:523	chemical design principles	498:523	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	3	45	theme	photosensitizers	850:865	arg1	role					818:821	the role	814:821	the role of the carrier polymer and photosensitizers concentration on its efficacy	814:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	46	theme	vinyl	676:680	arg1	poly					671:674	poly	671:674	poly(vinyl alcohol)	671:689	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	46	theme	vinyl	676:680	arg1	alcohol					682:688	vinyl alcohol	676:688	vinyl alcohol	676:688	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	47	theme	membranes	649:657	arg1	activities					608:617	the antibacterial and antiviral activities	576:617	the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	576:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	2	48	theme	research	448:455	arg1	area					440:443	an emerging and attractive area	413:443	an emerging and attractive area of research	413:455	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	2	49	theme	chemical	498:505	arg1	principles					514:523	chemical design principles	498:523	chemical design principles	498:523	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	1	50	theme	innovative	342:351	arg1	materials					353:361	new and innovative materials	334:361	new and innovative materials	334:361	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	6	51	theme	antimicrobial	1440:1452	arg1	therapy					1467:1473	topical antimicrobial photodynamic therapy	1432:1473	topical antimicrobial photodynamic therapy	1432:1473	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	5	52	from	amount	1162:1167	arg1	mixture					1196:1202	the polymer mixture	1184:1202	the polymer mixture	1184:1202	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	2	53	theme	photodynamic	383:394	arg1	action					396:401	photodynamic action	383:401	photodynamic action	383:401	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	0	54	theme	composition	55:65	arg1	Influence					0:8	Influence	0:8	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	0:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	1	55	theme	materials	353:361	arg1	development					319:329	development	319:329	development of new and innovative materials	319:361	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	0	56	theme	silicon	193:199	arg1	phthalocyanine					205:218	tailor-made silicon(IV) phthalocyanine	181:218	tailor-made silicon(IV) phthalocyanine	181:218	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	3	57	theme	vinyl	699:703	arg1	poly					694:697	poly	694:697	poly(vinyl alcohol)	694:712	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	57	theme	vinyl	699:703	arg1	alcohol					705:711	vinyl alcohol	699:711	vinyl alcohol	699:711	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	58	theme	different	627:635	arg1	membranes					649:657	five different nanofibrous membranes	622:657	five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	622:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	5	59	theme	studies	1122:1128	arg1	results					1093:1099	The results	1089:1099	The results of the antimicrobial studies	1089:1128	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	6	60	theme	light-triggered	1328:1342	arg1	activity					1358:1365	their visible light-triggered antimicrobial activity	1314:1365	their visible light-triggered antimicrobial activity	1314:1365	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	3	61	dep	polymer	838:844	arg1	concentration					867:879	concentration	867:879	concentration	867:879	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	61	dep	polymer	838:844	arg1	the					826:828	the	826:828	the	826:828	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	3	62	theme	poly	671:674	arg1	mixture					723:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture	671:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	671:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	6	63	theme	environmental	1491:1503	arg1	remediation					1505:1515	environmental remediation	1491:1515	environmental remediation	1491:1515	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	6	64	theme	visible	1320:1326	arg1	activity					1358:1365	their visible light-triggered antimicrobial activity	1314:1365	their visible light-triggered antimicrobial activity	1314:1365	Due to their visible light-triggered antimicrobial activity, the resulting materials provide valuable opportunities for both topical antimicrobial photodynamic therapy and the area of environmental remediation.					
35513693	3	65	theme	poly	694:697	arg1	mixture					723:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture	671:729	poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy	671:895	In the present study, we investigated the antibacterial and antiviral activities of five different nanofibrous membranes composed of poly(vinyl alcohol) or poly(vinyl alcohol)-chitosan mixture cross-linked through silicon(IV)phthalocyanine derivative with the aim to identify the role of the carrier polymer and photosensitizers concentration on its efficacy.					
35513693	5	66	from	increase	1221:1228	arg1	concentration					1253:1265	the photosensitizer concentration	1233:1265	the photosensitizer concentration	1233:1265	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	0	67	theme	antimicrobial	83:95	arg1	activity					97:104	photoinduced antimicrobial activity	70:104	photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	70:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	1	68	theme	pathogenic	253:262	arg1	bacteria					264:271	pathogenic bacteria	253:271	pathogenic bacteria	253:271	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	1	69	dep	effort	233:238	arg1	eradicate					243:251	eradicate	243:251	to eradicate pathogenic bacteria and viruses	240:283	The ongoing effort to eradicate pathogenic bacteria and viruses is a major endeavor that requires development of new and innovative materials.					
35513693	2	70	theme	emerging	416:423	arg1	area					440:443	an emerging and attractive area	413:443	an emerging and attractive area of research	413:455	Materials based on photodynamic action represent an emerging and attractive area of research, and therefore, a broad understanding of chemical design principles is required.					
35513693	0	71	theme	photoinduced	70:81	arg1	activity					97:104	photoinduced antimicrobial activity	70:104	photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials	70:161	Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.					
35513693	4	72	theme	electron	1068:1075	arg1	microscopy					1077:1086	scanning electron microscopy	1059:1086	scanning electron microscopy	1059:1086	A straightforward cross-linking process was adopted to create a water-stable material with an almost uniform distribution of the fiber structure, as revealed by scanning electron microscopy.					
35513693	5	73	from	increase	1146:1153	arg1	amount					1162:1167	the amount	1158:1167	the amount of chitosan in the polymer mixture	1158:1202	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
35513693	5	73	from	increase	1146:1153	arg1	chitosan					1172:1179	chitosan	1172:1179	chitosan	1172:1179	The results of the antimicrobial studies showed that the increase in the amount of chitosan in the polymer mixture, rather than the increase in the photosensitizer concentration, enhanced the activity of the material.					
36058392	0	0	theme	matter	92:97	arg1	removal					99:105	effective particulate matter removal	70:105	effective particulate matter removal	70:105	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	1	1	theme	serious	150:156	arg1	threat					158:163	a serious threat	148:163	a serious threat to public health	148:180	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	0	2	theme	particulate	80:90	arg1	removal					99:105	effective particulate matter removal	70:105	effective particulate matter removal	70:105	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	7	3	theme	degradable	1093:1102	arg1	materials					1126:1134	degradable and functional filter materials	1093:1134	degradable and functional filter materials	1093:1134	This work shows a new possibility for the design of degradable and functional filter materials.					
36058392	3	4	theme	PVA	526:528	arg1	content					507:513	The low content	499:513	The low content of CNF and PVA	499:528	The low content of CNF and PVA could be cross-linked by borax to form hydrogels, which enhanced its maneuverability for surface implanting on the substrate.					
36058392	3	5	theme	CNF	518:520	arg1	content					507:513	The low content	499:513	The low content of CNF and PVA	499:528	The low content of CNF and PVA could be cross-linked by borax to form hydrogels, which enhanced its maneuverability for surface implanting on the substrate.					
36058392	2	6	theme	CNF	335:337	arg1	aerogels					340:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	7	7	theme	new	1059:1061	arg1	possibility					1063:1073	a new possibility	1057:1073	a new possibility for the design of degradable and functional filter materials	1057:1134	This work shows a new possibility for the design of degradable and functional filter materials.					
36058392	3	8	theme	low	503:505	arg1	content					507:513	The low content	499:513	The low content of CNF and PVA	499:528	The low content of CNF and PVA could be cross-linked by borax to form hydrogels, which enhanced its maneuverability for surface implanting on the substrate.					
36058392	5	9	theme	composite	809:817	arg1	filters					823:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	2	10	theme	composite	478:486	arg1	hydrogels					488:496	the coated composite hydrogels	467:496	the coated composite hydrogels	467:496	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	0	11	theme	Nanocellulose	0:12	arg1	implantation					14:25	Nanocellulose implantation	0:25	Nanocellulose implantation	0:25	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	1	12	theme	public	168:173	arg1	health					175:180	public health	168:180	public health	168:180	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	2	13	theme	coated	471:476	arg1	hydrogels					488:496	the coated composite hydrogels	467:496	the coated composite hydrogels	467:496	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	5	14	theme	%	890:890	arg1	efficiencies					862:873	excellent filtration efficiencies	841:873	excellent filtration efficiencies of 92 % and 96 %	841:890	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	2	15	theme	air	418:420	arg1	filters					422:428	composite air filters	408:428	composite air filters for the first time	408:447	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	7	16	theme	filter	1119:1124	arg1	materials					1126:1134	degradable and functional filter materials	1093:1134	degradable and functional filter materials	1093:1134	This work shows a new possibility for the design of degradable and functional filter materials.					
36058392	2	17	theme	alcohol	292:298	arg1	aerogels					340:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	2	18	theme	composite	408:416	arg1	filters					422:428	composite air filters	408:428	composite air filters for the first time	408:447	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	1	19	from	problem	253:259	arg1	future					268:273	future	268:273	future	268:273	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	2	20	theme	polyvinyl	282:290	arg1	PVA					301:303	PVA	301:303	PVA	301:303	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	2	20	theme	polyvinyl	282:290	arg1	alcohol					292:298	polyvinyl alcohol	282:298	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	1	21	theme	disposable	183:192	arg1	materials					216:224	disposable and degradable filter materials	183:224	disposable and degradable filter materials	183:224	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	4	22	theme	CNF	690:692	arg1	addition					678:685	the addition	674:685	the addition of CNF	674:692	More importantly, the addition of CNF greatly enriched the pore structure of aerogels, which provided a structural basis for PM capture.					
36058392	4	23	theme	aerogels	733:740	arg1	structure					720:728	the pore structure	711:728	the pore structure	711:728	More importantly, the addition of CNF greatly enriched the pore structure of aerogels, which provided a structural basis for PM capture.					
36058392	1	24	theme	matter	120:125	arg1	pollution					132:140	Particulate matter (PM) pollution	108:140	Particulate matter (PM) pollution	108:140	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	7	25	theme	functional	1108:1117	arg1	materials					1126:1134	degradable and functional filter materials	1093:1134	degradable and functional filter materials	1093:1134	This work shows a new possibility for the design of degradable and functional filter materials.					
36058392	5	26	theme	%	881:881	arg1	efficiencies					862:873	excellent filtration efficiencies	841:873	excellent filtration efficiencies of 92 % and 96 %	841:890	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	1	27	theme	degradable	198:207	arg1	materials					216:224	disposable and degradable filter materials	183:224	disposable and degradable filter materials	183:224	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	2	28	theme	corrugated	383:392	arg1	paper					394:398	a biodegradable corrugated paper	367:398	a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels	367:496	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	0	29	theme	pore	40:43	arg1	structure					45:53	the pore structure	36:53	the pore structure of aerogel for effective particulate matter removal	36:105	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	2	30	theme	first	438:442	arg1	time					444:447	the first time	434:447	the first time	434:447	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	4	31	theme	pore	715:718	arg1	structure					720:728	the pore structure	711:728	the pore structure	711:728	More importantly, the addition of CNF greatly enriched the pore structure of aerogels, which provided a structural basis for PM capture.					
36058392	4	32	theme	structural	760:769	arg1	basis					771:775	a structural basis	758:775	a structural basis for PM capture	758:790	More importantly, the addition of CNF greatly enriched the pore structure of aerogels, which provided a structural basis for PM capture.					
36058392	5	33	theme	as-prepared	797:807	arg1	filters					823:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	2	34	theme	biodegradable	369:381	arg1	paper					394:398	a biodegradable corrugated paper	367:398	a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels	367:496	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	0	35	theme	aerogel	58:64	arg1	structure					45:53	the pore structure	36:53	the pore structure of aerogel for effective particulate matter removal	36:105	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	4	36	theme	PM	781:782	arg1	capture					784:790	PM capture	781:790	PM capture	781:790	More importantly, the addition of CNF greatly enriched the pore structure of aerogels, which provided a structural basis for PM capture.					
36058392	2	37	theme	nanofibrils	322:332	arg1	aerogels					340:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	6	38	with	endowed	989:995	arg1	property					1031:1038	an antibacterial property	1014:1038	an antibacterial property	1014:1038	Moreover, the addition of dimethylol-5,5-dimethylhydantoin endowed the filters with an antibacterial property.					
36058392	2	39	theme	/borax/cellulose	305:320	arg1	aerogels					340:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels	282:347	Here, polyvinyl alcohol (PVA)/borax/cellulose nanofibrils (CNF) aerogels were implanted on a biodegradable corrugated paper to form composite air filters for the first time via freeze-drying the coated composite hydrogels.					
36058392	7	40	theme	materials	1126:1134	arg1	design					1083:1088	the design	1079:1088	the design of degradable and functional filter materials	1079:1134	This work shows a new possibility for the design of degradable and functional filter materials.					
36058392	1	41	theme	Particulate	108:118	arg1	PM					128:129	PM	128:129	PM	128:129	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	1	41	theme	Particulate	108:118	arg1	matter					120:125	Particulate matter	108:125	Particulate matter (PM) pollution	108:140	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	3	42	theme	surface	619:625	arg1	implanting					627:636	surface implanting	619:636	surface implanting on the substrate	619:653	The low content of CNF and PVA could be cross-linked by borax to form hydrogels, which enhanced its maneuverability for surface implanting on the substrate.					
36058392	0	43	theme	effective	70:78	arg1	removal					99:105	effective particulate matter removal	70:105	effective particulate matter removal	70:105	Nanocellulose implantation enriched the pore structure of aerogel for effective particulate matter removal.					
36058392	1	44	theme	filter	209:214	arg1	materials					216:224	disposable and degradable filter materials	183:224	disposable and degradable filter materials	183:224	Particulate matter (PM) pollution poses a serious threat to public health, disposable and degradable filter materials are expected to handle the problem in the future.					
36058392	6	45	theme	antibacterial	1017:1029	arg1	property					1031:1038	an antibacterial property	1014:1038	an antibacterial property	1014:1038	Moreover, the addition of dimethylol-5,5-dimethylhydantoin endowed the filters with an antibacterial property.					
36058392	5	46	theme	excellent	841:849	arg1	efficiencies					862:873	excellent filtration efficiencies	841:873	excellent filtration efficiencies of 92 % and 96 %	841:890	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	5	47	theme	air	819:821	arg1	filters					823:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters	793:829	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36058392	6	48	theme	dimethylol-5,5-dimethylhydantoin	956:987	arg1	addition					944:951	the addition	940:951	the addition of dimethylol-5,5-dimethylhydantoin	940:987	Moreover, the addition of dimethylol-5,5-dimethylhydantoin endowed the filters with an antibacterial property.					
36058392	3	49	from	implanting	627:636	arg1	substrate					645:653	the substrate	641:653	the substrate	641:653	The low content of CNF and PVA could be cross-linked by borax to form hydrogels, which enhanced its maneuverability for surface implanting on the substrate.					
36058392	5	50	theme	filtration	851:860	arg1	efficiencies					862:873	excellent filtration efficiencies	841:873	excellent filtration efficiencies of 92 % and 96 %	841:890	The as-prepared composite air filters exhibited excellent filtration efficiencies of 92 % and 96 % toward PM1.0 and PM3.0, respectively.					
36153627	6	0	theme	molecular	1034:1042	arg1	weight					1044:1049	a homogeneous molecular weight	1020:1049	a homogeneous molecular weight of 5655 Da	1020:1060	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	1	1	theme	dietary	224:230	arg1	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	1	theme	dietary	224:230	arg1	supplement					232:241	dietary supplement	224:241	dietary supplement	224:241	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	10	2	contain	possessed	1592:1600	arg2	activity					1621:1628	strong antioxidant activity	1602:1628	strong antioxidant activity	1602:1628	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	2	contain	possessed	1592:1600	arg1	RGP1-1					1585:1590	RGP1-1	1585:1590	RGP1-1	1585:1590	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	12	3	theme	natural	2374:2380	arg1	antioxidant					2382:2392	novel natural antioxidant	2368:2392	novel natural antioxidant	2368:2392	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	4	4	theme	monosaccharide	551:564	arg1	linkages					523:530	glycosyl linkages	514:530	glycosyl linkages	514:530	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	4	theme	monosaccharide	551:564	arg1	composition					566:576	monosaccharide composition	551:576	monosaccharide composition	551:576	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	2	5	theme	few	253:255	arg1	researches					257:266	few researches	253:266	few researches	253:266	However, few researches had been reported on the red ginseng polysaccharide (RGP).					
36153627	4	6	theme	differential	784:795	arg1	DSC-TG					846:851	DSC-TG	846:851	DSC-TG	846:851	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	6	theme	differential	784:795	arg1	analysis					836:843	differential scanning calorimetry-thermogravimetric analysis	784:843	differential scanning calorimetry-thermogravimetric analysis (DSC-TG)	784:852	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	6	theme	differential	784:795	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	spectrometer					695:706	gas chromatography-mass spectrometer	671:706	gas chromatography-mass spectrometer (GC-MS)	671:714	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	microscope					730:739	atomic force microscope	717:739	atomic force microscope (AFM)	717:745	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	NMR					665:667	NMR	665:667	NMR	665:667	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	microscope					766:775	scanning electron microscope	748:775	scanning electron microscope (SEM)	748:781	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	analysis					836:843	differential scanning calorimetry-thermogravimetric analysis	784:843	differential scanning calorimetry-thermogravimetric analysis (DSC-TG)	784:852	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	7	theme	nuclear	637:643	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	10	8	theme	lactate	1863:1869	arg1	troponin					1812:1819	cardiac troponin	1804:1819	cardiac troponin (cTnI)	1804:1826	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	8	theme	lactate	1863:1869	arg1	LDH					1886:1888	LDH	1886:1888	LDH	1886:1888	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	8	theme	lactate	1863:1869	arg1	dehydrogenase					1871:1883	lactate dehydrogenase	1863:1883	lactate dehydrogenase (LDH)	1863:1889	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	11	9	theme	blot	1923:1926	arg1	analysis					1928:1935	Western blot analysis	1915:1935	Western blot analysis	1915:1935	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	4	10	theme	calorimetry-thermogravimetric	806:834	arg1	DSC-TG					846:851	DSC-TG	846:851	DSC-TG	846:851	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	10	theme	calorimetry-thermogravimetric	806:834	arg1	analysis					836:843	differential scanning calorimetry-thermogravimetric analysis	784:843	differential scanning calorimetry-thermogravimetric analysis (DSC-TG)	784:852	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	10	theme	calorimetry-thermogravimetric	806:834	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	11	11	theme	kelch-like	2110:2119	arg1	keap1					2145:2149	keap1	2145:2149	keap1	2145:2149	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	11	theme	kelch-like	2110:2119	arg1	protein1					2136:2143	kelch-like ECH-associated protein1	2110:2143	kelch-like ECH-associated protein1(keap1) in oxidative stress	2110:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	0	12	from	injury	108:113	arg1	ischemia					129:136	myocardial ischemia	118:136	myocardial ischemia	118:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	12	13	theme	myocardial	2329:2338	arg1	injury					2349:2354	ISO-induced myocardial ischemia injury	2317:2354	ISO-induced myocardial ischemia injury in mice	2317:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	1	14	theme	Chinese	198:204	arg1	TCM					216:218	TCM	216:218	TCM	216:218	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	14	theme	Chinese	198:204	arg1	medicine					206:213	traditional Chinese medicine	186:213	traditional Chinese medicine (TCM)	186:219	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	14	theme	Chinese	198:204	arg1	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	11	15	theme	factor	2008:2013	arg1	factor					2026:2031	main protein Nuclear factor E2-related factor 2	1987:2033	main protein Nuclear factor E2-related factor 2(Nrf2)	1987:2039	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	15	theme	factor	2008:2013	arg1	Nrf2					2035:2038	Nrf2	2035:2038	Nrf2	2035:2038	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	4	16	theme	chromatography-mass	675:693	arg1	GC-MS					709:713	GC-MS	709:713	GC-MS	709:713	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	16	theme	chromatography-mass	675:693	arg1	spectrometer					695:706	gas chromatography-mass spectrometer	671:706	gas chromatography-mass spectrometer (GC-MS)	671:714	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	16	theme	chromatography-mass	675:693	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	11	17	theme	protein	1992:1998	arg1	factor					2026:2031	main protein Nuclear factor E2-related factor 2	1987:2033	main protein Nuclear factor E2-related factor 2(Nrf2)	1987:2039	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	17	theme	protein	1992:1998	arg1	Nrf2					2035:2038	Nrf2	2035:2038	Nrf2	2035:2038	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	8	18	theme	irregular	1379:1387	arg1	structure					1399:1407	irregular spherical structure	1379:1407	irregular spherical structure	1379:1407	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	12	19	dep	CONCLUSION	2238:2247	arg1	indicated					2268:2276	indicated	2268:2276	indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs	2268:2419	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	10	20	theme	serum	1788:1792	arg1	levels					1794:1799	the serum levels	1784:1799	the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA)	1784:1912	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	5	21	theme	RGP1-1	879:884	arg1	effect					869:874	The effect	865:874	The effect of RGP1-1 in preventing and treating myocardial ischemia	865:931	The effect of RGP1-1 in preventing and treating myocardial ischemia was evaluated by an animal model isoprenaline (ISO) induced mice.					
36153627	10	22	from	fibrosis	1713:1720	arg1	histopathology					1733:1746	histopathology	1733:1746	histopathology	1733:1746	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	11	23	from	protein1	2136:2143	arg1	stress					2165:2170	oxidative stress	2155:2170	oxidative stress	2155:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	1	24	theme	Red	150:152	arg1	supplement					232:241	dietary supplement	224:241	dietary supplement	224:241	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	24	theme	Red	150:152	arg1	RG					163:164	RG	163:164	RG	163:164	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	24	theme	Red	150:152	arg1	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	24	theme	Red	150:152	arg1	medicine					206:213	traditional Chinese medicine	186:213	traditional Chinese medicine (TCM)	186:219	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	8	25	theme	molecule	1414:1421	arg1	aggregations					1423:1434	molecule aggregations	1414:1434	molecule aggregations	1414:1434	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	3	26	dep	METHODS	327:333	arg1	study					343:347	this study	338:347	this study	338:347	METHODS In this study, a novel heteropolysaccharide named RGP1-1 was fractionated sequentially by DEAE-52 column and Sephadex G-100 gel column.					
36153627	0	27	theme	ameliorative	68:79	arg1	effect					81:86	its ameliorative effect	64:86	its ameliorative effect on oxidative stress injury in myocardial ischemia	64:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	28	from	Characterization	0:15	arg1	injury					108:113	oxidative stress injury	91:113	oxidative stress injury in myocardial ischemia	91:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	28	from	Characterization	0:15	arg1	ginseng					52:58	red ginseng	48:58	red ginseng	48:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	11	29	theme	Nrf2/HO-1	2227:2235	arg1	pathway					2216:2222	the pathway	2212:2222	the pathway of Nrf2/HO-1	2212:2235	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	7	30	theme	methylation	1123:1133	arg1	analysis					1143:1150	The methylation and NMR analysis	1119:1150	analysis	1143:1150	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	10	31	theme	myocardium	1702:1711	arg1	fibrosis					1713:1720	myocardium fibrosis	1702:1720	myocardium fibrosis	1702:1720	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	8	32	theme	thermal	1447:1453	arg1	properties					1455:1464	stable thermal properties	1440:1464	stable thermal properties of RGP1-1	1440:1474	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	10	33	theme	strong	1602:1607	arg1	activity					1621:1628	strong antioxidant activity	1602:1628	strong antioxidant activity	1602:1628	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	0	34	theme	stress	101:106	arg1	injury					108:113	oxidative stress injury	91:113	oxidative stress injury in myocardial ischemia	91:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	12	35	from	injury	2349:2354	arg1	mice					2359:2362	mice	2359:2362	mice	2359:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	9	36	theme	zeta	1502:1505	arg1	potential					1507:1515	6.82 mV zeta potential	1494:1515	6.82 mV zeta potential	1494:1515	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	11	37	theme	P	2046:2046	arg1	H					2048:2048	NAD(P)H	2042:2048	NAD(P)H	2042:2048	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	4	38	theme	atomic	717:722	arg1	microscope					730:739	atomic force microscope	717:739	atomic force microscope (AFM)	717:745	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	38	theme	atomic	717:722	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	38	theme	atomic	717:722	arg1	AFM					742:744	AFM	742:744	AFM	742:744	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	7	39	theme	-Galp-	1214:1219	arg1	4 →					1221:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	3	40	theme	novel	352:356	arg1	heteropolysaccharide					358:377	a novel heteropolysaccharide	350:377	a novel heteropolysaccharide named RGP1-1	350:390	METHODS In this study, a novel heteropolysaccharide named RGP1-1 was fractionated sequentially by DEAE-52 column and Sephadex G-100 gel column.					
36153627	12	41	theme	improving	2297:2305	arg1	drugs					2415:2419	heart-protecting drugs	2398:2419	heart-protecting drugs	2398:2419	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	12	41	theme	improving	2297:2305	arg1	effect					2307:2312	an improving effect	2294:2312	an improving effect on ISO-induced myocardial ischemia injury in mice	2294:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	10	42	theme	troponin	1812:1819	arg1	levels					1794:1799	the serum levels	1784:1799	the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA)	1784:1912	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	8	43	with	properties	1455:1464	arg1	aggregations					1423:1434	molecule aggregations	1414:1434	molecule aggregations	1414:1434	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	0	44	theme	polysaccharide	28:41	arg1	Characterization					0:15	Characterization	0:15	Characterization of a novel polysaccharide from red ginseng	0:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	44	theme	polysaccharide	28:41	arg1	effect					81:86	its ameliorative effect	64:86	its ameliorative effect on oxidative stress injury in myocardial ischemia	64:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	9	45	theme	partical	1527:1534	arg1	size					1536:1539	117.4 nm partical size	1518:1539	117.4 nm partical size	1518:1539	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	7	46	theme	4 → and → 1	1202:1212	arg1	4 →					1221:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	11	47	theme	quinone	2050:2056	arg1	oxidoreductase					2058:2071	quinone oxidoreductase 1	2050:2073	quinone oxidoreductase 1 (NQO1)	2050:2080	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	47	theme	quinone	2050:2056	arg1	NQO1					2076:2079	NQO1	2076:2079	NQO1	2076:2079	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	8	48	theme	property	1311:1318	arg1	analysis					1320:1327	Morphology and physicochemical property analysis	1280:1327	Morphology and physicochemical property analysis	1280:1327	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	11	49	from	H	2048:2048	arg1	stress					2165:2170	oxidative stress	2155:2170	oxidative stress	2155:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	3	50	theme	G-100	453:457	arg1	column					463:468	Sephadex G-100 gel column	444:468	Sephadex G-100 gel column	444:468	METHODS In this study, a novel heteropolysaccharide named RGP1-1 was fractionated sequentially by DEAE-52 column and Sephadex G-100 gel column.					
36153627	0	51	theme	red	48:50	arg1	ginseng					52:58	red ginseng	48:58	red ginseng	48:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	7	52	dep	branched	1226:1233	arg1	1 → residue					1267:1277	1 → residue	1267:1277	1 → residue	1267:1277	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	7	53	theme	-Glcp-	1195:1200	arg1	4 →					1221:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	→ 1)-Glcp-(4 → and → 1)-Galp-(4 →	1191:1223	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	12	54	theme	heart-protecting	2398:2413	arg1	drugs					2415:2419	heart-protecting drugs	2398:2419	heart-protecting drugs	2398:2419	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	12	54	theme	heart-protecting	2398:2413	arg1	effect					2307:2312	an improving effect	2294:2312	an improving effect on ISO-induced myocardial ischemia injury in mice	2294:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	4	55	theme	RGP1-1	496:501	arg1	structure					483:491	The primary structure	471:491	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property	471:617	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	7	56	dep	4 →	1221:1223	arg1	composed					1179:1186	composed	1179:1186	composed	1179:1186	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	7	56	dep	4 →	1221:1223	arg1	branched					1226:1233	branched	1226:1233	branched partially at O-4 with α-D-Glcp-(1 → residue	1226:1277	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	2	57	theme	red	293:295	arg1	RGP					321:323	RGP	321:323	RGP	321:323	However, few researches had been reported on the red ginseng polysaccharide (RGP).					
36153627	2	57	theme	red	293:295	arg1	polysaccharide					305:318	the red ginseng polysaccharide	289:318	the red ginseng polysaccharide (RGP)	289:324	However, few researches had been reported on the red ginseng polysaccharide (RGP).					
36153627	6	58	theme	5655 Da	1054:1060	arg1	weight					1044:1049	a homogeneous molecular weight	1020:1049	a homogeneous molecular weight of 5655 Da	1020:1060	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	11	59	theme	oxidative	2155:2163	arg1	stress					2165:2170	oxidative stress	2155:2170	oxidative stress	2155:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	9	60	contain	contained	1484:1492	arg1	it					1481:1482	it	1481:1482	it	1481:1482	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	9	60	contain	contained	1484:1492	arg2	phenomenon					1560:1569	polymerization phenomenon	1545:1569	polymerization phenomenon	1545:1569	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	9	60	contain	contained	1484:1492	arg2	potential					1507:1515	6.82 mV zeta potential	1494:1515	6.82 mV zeta potential	1494:1515	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	9	60	contain	contained	1484:1492	arg2	size					1536:1539	117.4 nm partical size	1518:1539	117.4 nm partical size	1518:1539	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	8	61	theme	triple-helical	1340:1353	arg1	conformation					1355:1366	a triple-helical conformation	1338:1366	a triple-helical conformation	1338:1366	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	10	62	theme	cardiomyocyte	1674:1686	arg1	apoptosis					1688:1696	cardiomyocyte apoptosis	1674:1696	cardiomyocyte apoptosis	1674:1696	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	12	63	theme	novel	2368:2372	arg1	antioxidant					2382:2392	novel natural antioxidant	2368:2392	novel natural antioxidant	2368:2392	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	11	64	from	oxidoreductase	2058:2071	arg1	stress					2165:2170	oxidative stress	2155:2170	oxidative stress	2155:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	65	theme	NAD	2042:2044	arg1	H					2048:2048	NAD(P)H	2042:2048	NAD(P)H	2042:2048	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	6	66	theme	homogeneous	1022:1032	arg1	weight					1044:1049	a homogeneous molecular weight	1020:1049	a homogeneous molecular weight of 5655 Da	1020:1060	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	4	67	theme	molecular	533:541	arg1	linkages					523:530	glycosyl linkages	514:530	glycosyl linkages	514:530	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	67	theme	molecular	533:541	arg1	weight					543:548	molecular weight	533:548	molecular weight	533:548	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	11	68	theme	ECH-associated	2121:2134	arg1	keap1					2145:2149	keap1	2145:2149	keap1	2145:2149	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	68	theme	ECH-associated	2121:2134	arg1	protein1					2136:2143	kelch-like ECH-associated protein1	2110:2143	kelch-like ECH-associated protein1(keap1) in oxidative stress	2110:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	69	theme	Western	1915:1921	arg1	analysis					1928:1935	Western blot analysis	1915:1935	Western blot analysis	1915:1935	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	4	70	dep	and	854:856	arg1	so					858:859	so	858:859	so	858:859	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	7	71	theme	NMR	1139:1141	arg1	analysis					1143:1150	The methylation and NMR analysis	1119:1150	analysis	1143:1150	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	8	72	theme	stable	1440:1445	arg1	properties					1455:1464	stable thermal properties	1440:1464	stable thermal properties of RGP1-1	1440:1474	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	4	73	theme	scanning	797:804	arg1	DSC-TG					846:851	DSC-TG	846:851	DSC-TG	846:851	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	73	theme	scanning	797:804	arg1	analysis					836:843	differential scanning calorimetry-thermogravimetric analysis	784:843	differential scanning calorimetry-thermogravimetric analysis (DSC-TG)	784:852	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	73	theme	scanning	797:804	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	12	74	theme	ISO-induced	2317:2327	arg1	injury					2349:2354	ISO-induced myocardial ischemia injury	2317:2354	ISO-induced myocardial ischemia injury in mice	2317:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	4	75	theme	magnetic	645:652	arg1	spectrometer					695:706	gas chromatography-mass spectrometer	671:706	gas chromatography-mass spectrometer (GC-MS)	671:714	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	75	theme	magnetic	645:652	arg1	microscope					730:739	atomic force microscope	717:739	atomic force microscope (AFM)	717:745	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	75	theme	magnetic	645:652	arg1	NMR					665:667	NMR	665:667	NMR	665:667	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	75	theme	magnetic	645:652	arg1	microscope					766:775	scanning electron microscope	748:775	scanning electron microscope (SEM)	748:781	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	75	theme	magnetic	645:652	arg1	analysis					836:843	differential scanning calorimetry-thermogravimetric analysis	784:843	differential scanning calorimetry-thermogravimetric analysis (DSC-TG)	784:852	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	75	theme	magnetic	645:652	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	0	76	theme	myocardial	118:127	arg1	ischemia					129:136	myocardial ischemia	118:136	myocardial ischemia	118:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	10	77	theme	mice	1725:1728	arg1	apoptosis					1688:1696	cardiomyocyte apoptosis	1674:1696	cardiomyocyte apoptosis	1674:1696	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	77	theme	mice	1725:1728	arg1	fibrosis					1713:1720	myocardium fibrosis	1702:1720	myocardium fibrosis	1702:1720	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	11	78	theme	main	1987:1990	arg1	factor					2026:2031	main protein Nuclear factor E2-related factor 2	1987:2033	main protein Nuclear factor E2-related factor 2(Nrf2)	1987:2039	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	78	theme	main	1987:1990	arg1	Nrf2					2035:2038	Nrf2	2035:2038	Nrf2	2035:2038	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	0	79	from	effect	81:86	arg1	injury					108:113	oxidative stress injury	91:113	oxidative stress injury in myocardial ischemia	91:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	79	from	effect	81:86	arg1	ginseng					52:58	red ginseng	48:58	red ginseng	48:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	12	80	theme	ischemia	2340:2347	arg1	injury					2349:2354	ISO-induced myocardial ischemia injury	2317:2354	ISO-induced myocardial ischemia injury in mice	2317:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	5	81	dep	model	960:964	arg1	induced					985:991	induced	985:991	induced mice	985:996	The effect of RGP1-1 in preventing and treating myocardial ischemia was evaluated by an animal model isoprenaline (ISO) induced mice.					
36153627	3	82	theme	gel	459:461	arg1	column					463:468	Sephadex G-100 gel column	444:468	Sephadex G-100 gel column	444:468	METHODS In this study, a novel heteropolysaccharide named RGP1-1 was fractionated sequentially by DEAE-52 column and Sephadex G-100 gel column.					
36153627	12	83	from	effect	2307:2312	arg1	injury					2349:2354	ISO-induced myocardial ischemia injury	2317:2354	ISO-induced myocardial ischemia injury in mice	2317:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	1	84	theme	traditional	186:196	arg1	TCM					216:218	TCM	216:218	TCM	216:218	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	84	theme	traditional	186:196	arg1	medicine					206:213	traditional Chinese medicine	186:213	traditional Chinese medicine (TCM)	186:219	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	84	theme	traditional	186:196	arg1	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	11	85	theme	E2-related	2015:2024	arg1	factor					2026:2031	main protein Nuclear factor E2-related factor 2	1987:2033	main protein Nuclear factor E2-related factor 2(Nrf2)	1987:2039	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	85	theme	E2-related	2015:2024	arg1	Nrf2					2035:2038	Nrf2	2035:2038	Nrf2	2035:2038	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	8	86	theme	spherical	1389:1397	arg1	structure					1399:1407	irregular spherical structure	1379:1407	irregular spherical structure	1379:1407	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	1	87	used	used	178:181	arg2	RG					163:164	RG	163:164	RG	163:164	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	87	used	used	178:181	arg2	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	87	used	used	178:181	arg2	supplement					232:241	dietary supplement	224:241	dietary supplement	224:241	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	87	used	used	178:181	arg2	medicine					206:213	traditional Chinese medicine	186:213	traditional Chinese medicine (TCM)	186:219	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	4	88	theme	gas	671:673	arg1	GC-MS					709:713	GC-MS	709:713	GC-MS	709:713	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	88	theme	gas	671:673	arg1	spectrometer					695:706	gas chromatography-mass spectrometer	671:706	gas chromatography-mass spectrometer (GC-MS)	671:714	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	88	theme	gas	671:673	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	10	89	from	apoptosis	1688:1696	arg1	histopathology					1733:1746	histopathology	1733:1746	histopathology	1733:1746	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	11	90	theme	Nuclear	2000:2006	arg1	factor					2026:2031	main protein Nuclear factor E2-related factor 2	1987:2033	main protein Nuclear factor E2-related factor 2(Nrf2)	1987:2039	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	90	theme	Nuclear	2000:2006	arg1	Nrf2					2035:2038	Nrf2	2035:2038	Nrf2	2035:2038	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	2	91	theme	ginseng	297:303	arg1	RGP					321:323	RGP	321:323	RGP	321:323	However, few researches had been reported on the red ginseng polysaccharide (RGP).					
36153627	2	91	theme	ginseng	297:303	arg1	polysaccharide					305:318	the red ginseng polysaccharide	289:318	the red ginseng polysaccharide (RGP)	289:324	However, few researches had been reported on the red ginseng polysaccharide (RGP).					
36153627	1	92	theme	BACKGROUND	139:148	arg1	supplement					232:241	dietary supplement	224:241	dietary supplement	224:241	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	92	theme	BACKGROUND	139:148	arg1	RG					163:164	RG	163:164	RG	163:164	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	92	theme	BACKGROUND	139:148	arg1	ginseng					154:160	BACKGROUND Red ginseng	139:160	BACKGROUND Red ginseng (RG)	139:165	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	1	92	theme	BACKGROUND	139:148	arg1	medicine					206:213	traditional Chinese medicine	186:213	traditional Chinese medicine (TCM)	186:219	BACKGROUND Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement.					
36153627	11	93	theme	heme	2083:2086	arg1	HO-1					2100:2103	HO-1	2100:2103	HO-1	2100:2103	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	11	93	theme	heme	2083:2086	arg1	oxygenase-1					2088:2098	heme oxygenase-1	2083:2098	heme oxygenase-1(HO-1)	2083:2104	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	6	94	theme	94.26:4.92	1107:1116	arg1	ratio					1098:1102	the ratio	1094:1102	the ratio of 94.26:4.92	1094:1116	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	12	95	contain	had	2290:2292	arg2	effect					2307:2312	an improving effect	2294:2312	an improving effect on ISO-induced myocardial ischemia injury in mice	2294:2362	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	12	95	contain	had	2290:2292	arg1	RGP1-1					2283:2288	RGP1-1	2283:2288	RGP1-1	2283:2288	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	12	95	contain	had	2290:2292	arg2	drugs					2415:2419	heart-protecting drugs	2398:2419	heart-protecting drugs	2398:2419	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	7	96	with	O-4	1248:1250	arg1	α-D-Glcp-					1257:1265	α-D-Glcp-	1257:1265	α-D-Glcp-	1257:1265	The methylation and NMR analysis indicated the backbone was composed of → 1)-Glcp-(4 → and → 1)-Galp-(4 →, branched partially at O-4 with α-D-Glcp-(1 → residue.					
36153627	4	97	theme	primary	475:481	arg1	structure					483:491	The primary structure	471:491	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property	471:617	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	0	98	theme	oxidative	91:99	arg1	injury					108:113	oxidative stress injury	91:113	oxidative stress injury in myocardial ischemia	91:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	5	99	theme	myocardial	913:922	arg1	ischemia					924:931	myocardial ischemia	913:931	myocardial ischemia	913:931	The effect of RGP1-1 in preventing and treating myocardial ischemia was evaluated by an animal model isoprenaline (ISO) induced mice.					
36153627	0	100	from	ginseng	52:58	arg1	Characterization					0:15	Characterization	0:15	Characterization of a novel polysaccharide from red ginseng	0:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	100	from	ginseng	52:58	arg1	effect					81:86	its ameliorative effect	64:86	its ameliorative effect on oxidative stress injury in myocardial ischemia	64:136	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	0	100	from	ginseng	52:58	arg1	polysaccharide					28:41	a novel polysaccharide	20:41	a novel polysaccharide from red ginseng	20:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	4	101	theme	force	724:728	arg1	microscope					730:739	atomic force microscope	717:739	atomic force microscope (AFM)	717:745	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	101	theme	force	724:728	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	101	theme	force	724:728	arg1	AFM					742:744	AFM	742:744	AFM	742:744	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	3	102	theme	Sephadex	444:451	arg1	column					463:468	Sephadex G-100 gel column	444:468	Sephadex G-100 gel column	444:468	METHODS In this study, a novel heteropolysaccharide named RGP1-1 was fractionated sequentially by DEAE-52 column and Sephadex G-100 gel column.					
36153627	4	103	theme	physicochemical	594:608	arg1	linkages					523:530	glycosyl linkages	514:530	glycosyl linkages	514:530	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	103	theme	physicochemical	594:608	arg1	property					610:617	physicochemical property	594:617	physicochemical property	594:617	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	8	104	theme	RGP1-1	1469:1474	arg1	flaky					1369:1373	flaky	1369:1373	flaky	1369:1373	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	8	104	theme	RGP1-1	1469:1474	arg1	properties					1455:1464	stable thermal properties	1440:1464	stable thermal properties of RGP1-1	1440:1474	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	8	104	theme	RGP1-1	1469:1474	arg1	conformation					1355:1366	a triple-helical conformation	1338:1366	a triple-helical conformation	1338:1366	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	8	104	theme	RGP1-1	1469:1474	arg1	structure					1399:1407	irregular spherical structure	1379:1407	irregular spherical structure	1379:1407	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	9	105	theme	6.82 mV	1494:1500	arg1	potential					1507:1515	6.82 mV zeta potential	1494:1515	6.82 mV zeta potential	1494:1515	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	4	106	theme	glycosyl	514:521	arg1	morphology					579:588	morphology	579:588	morphology	579:588	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	106	theme	glycosyl	514:521	arg1	linkages					523:530	glycosyl linkages	514:530	glycosyl linkages	514:530	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	106	theme	glycosyl	514:521	arg1	property					610:617	physicochemical property	594:617	physicochemical property	594:617	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	106	theme	glycosyl	514:521	arg1	composition					566:576	monosaccharide composition	551:576	monosaccharide composition	551:576	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	106	theme	glycosyl	514:521	arg1	weight					543:548	molecular weight	533:548	molecular weight	533:548	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	0	107	theme	novel	22:26	arg1	polysaccharide					28:41	a novel polysaccharide	20:41	a novel polysaccharide from red ginseng	20:58	Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia.					
36153627	4	108	theme	electron	757:764	arg1	SEM					778:780	SEM	778:780	SEM	778:780	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	108	theme	electron	757:764	arg1	microscope					766:775	scanning electron microscope	748:775	scanning electron microscope (SEM)	748:781	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	108	theme	electron	757:764	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	6	109	theme	RESULTS	999:1005	arg1	RGP1-1					1007:1012	RESULTS RGP1-1	999:1012	RESULTS RGP1-1	999:1012	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	11	110	from	oxygenase-1	2088:2098	arg1	stress					2165:2170	oxidative stress	2155:2170	oxidative stress	2155:2170	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	6	111	with	RGP1-1	1007:1012	arg1	weight					1044:1049	a homogeneous molecular weight	1020:1049	a homogeneous molecular weight of 5655 Da	1020:1060	RESULTS RGP1-1, with a homogeneous molecular weight of 5655 Da, was composed of Glc and Gal in the ratio of 94.26:4.92.					
36153627	9	112	theme	117.4 nm	1518:1525	arg1	size					1536:1539	117.4 nm partical size	1518:1539	117.4 nm partical size	1518:1539	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	10	113	theme	cardiac	1804:1810	arg1	troponin					1812:1819	cardiac troponin	1804:1819	cardiac troponin (cTnI)	1804:1826	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	113	theme	cardiac	1804:1810	arg1	aminotransferase					1839:1854	aspartate aminotransferase	1829:1854	aspartate aminotransferase (AST)	1829:1860	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	113	theme	cardiac	1804:1810	arg1	malondialdehyde					1892:1906	malondialdehyde	1892:1906	malondialdehyde (MDA)	1892:1912	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	113	theme	cardiac	1804:1810	arg1	dehydrogenase					1871:1883	lactate dehydrogenase	1863:1883	lactate dehydrogenase (LDH)	1863:1889	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	113	theme	cardiac	1804:1810	arg1	cTnI					1822:1825	cTnI	1822:1825	cTnI	1822:1825	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	8	114	theme	Morphology	1280:1289	arg1	analysis					1320:1327	Morphology and physicochemical property analysis	1280:1327	Morphology and physicochemical property analysis	1280:1327	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	10	115	theme	antioxidant	1609:1619	arg1	activity					1621:1628	strong antioxidant activity	1602:1628	strong antioxidant activity	1602:1628	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	116	theme	aspartate	1829:1837	arg1	AST					1857:1859	AST	1857:1859	AST	1857:1859	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	116	theme	aspartate	1829:1837	arg1	troponin					1812:1819	cardiac troponin	1804:1819	cardiac troponin (cTnI)	1804:1826	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	10	116	theme	aspartate	1829:1837	arg1	aminotransferase					1839:1854	aspartate aminotransferase	1829:1854	aspartate aminotransferase (AST)	1829:1860	Furthermore, RGP1-1 possessed strong antioxidant activity in vitro and in vivo, RGP1-1 could decrease cardiomyocyte apoptosis and myocardium fibrosis of mice in histopathology and it could decrease significantly the serum levels of cardiac troponin (cTnI), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), malondialdehyde (MDA).					
36153627	8	117	theme	physicochemical	1295:1309	arg1	property					1311:1318	physicochemical property	1295:1318	physicochemical property	1295:1318	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	8	118	with	flaky	1369:1373	arg1	aggregations					1423:1434	molecule aggregations	1414:1434	molecule aggregations	1414:1434	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	9	119	theme	polymerization	1545:1558	arg1	phenomenon					1560:1569	polymerization phenomenon	1545:1569	polymerization phenomenon	1545:1569	And it contained 6.82 mV zeta potential, 117.4 nm partical size and polymerization phenomenon.					
36153627	8	120	with	conformation	1355:1366	arg1	aggregations					1423:1434	molecule aggregations	1414:1434	molecule aggregations	1414:1434	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36153627	5	121	theme	animal	953:958	arg1	model					960:964	an animal model	950:964	an animal model isoprenaline (ISO) induced mice	950:996	The effect of RGP1-1 in preventing and treating myocardial ischemia was evaluated by an animal model isoprenaline (ISO) induced mice.					
36153627	12	122	theme	above	2253:2257	arg1	findings					2259:2266	The above findings	2249:2266	The above findings	2249:2266	CONCLUSION The above findings indicated that RGP1-1 had an improving effect on ISO-induced myocardial ischemia injury in mice, as novel natural antioxidant and heart-protecting drugs.					
36153627	11	123	dep	expression	1973:1982	arg1	injure					2172:2177	injure	2172:2177	injure progress	2172:2186	Western blot analysis showed that RGP1-1 can increase the expression of main protein Nuclear factor E2-related factor 2(Nrf2), NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase-1(HO-1) and kelch-like ECH-associated protein1(keap1) in oxidative stress injure progress, and therefore regulate the pathway of Nrf2/HO-1.					
36153627	4	124	theme	scanning	748:755	arg1	SEM					778:780	SEM	778:780	SEM	778:780	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	124	theme	scanning	748:755	arg1	microscope					766:775	scanning electron microscope	748:775	scanning electron microscope (SEM)	748:781	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	4	124	theme	scanning	748:755	arg1	resonance					654:662	nuclear magnetic resonance	637:662	nuclear magnetic resonance (NMR)	637:668	The primary structure of RGP1-1, including glycosyl linkages, molecular weight, monosaccharide composition, morphology and physicochemical property were conducted by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometer (GC-MS), atomic force microscope (AFM), scanning electron microscope (SEM), differential scanning calorimetry-thermogravimetric analysis (DSC-TG) and so on.					
36153627	8	125	with	structure	1399:1407	arg1	aggregations					1423:1434	molecule aggregations	1414:1434	molecule aggregations	1414:1434	Morphology and physicochemical property analysis revealed a triple-helical conformation, flaky and irregular spherical structure with molecule aggregations and stable thermal properties of RGP1-1.					
36329067	6	0	theme	behaviour	957:965	arg1	values					981:986	thermal behaviour and calorific values	949:986	thermal behaviour and calorific values	949:986	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	13	1	theme	tested	1816:1821	arg1	feedstock					1871:1879	a feedstock	1869:1879	a feedstock in biorefinery for bioenergy	1869:1908	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	13	1	theme	tested	1816:1821	arg1	biomass					1823:1829	the tested biomass	1812:1829	the tested biomass	1812:1829	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	13	1	theme	tested	1816:1821	arg1	juliflora					1841:1849	Prosopis juliflora	1832:1849	Prosopis juliflora	1832:1849	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	9	2	theme	moisture	1218:1225	arg1	87.67 ± 0.002					1257:1269	volatile matter 87.67 ± 0.002	1241:1269	volatile matter 87.67 ± 0.002	1241:1269	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	2	theme	moisture	1218:1225	arg1	0.21 ± 0.002					1276:1287	ash 0.21 ± 0.002	1272:1287	ash 0.21 ± 0.002	1272:1287	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	2	theme	moisture	1218:1225	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	2	theme	moisture	1218:1225	arg1	4.23 ± 0.002					1303:1314	fixed carbon 4.23 ± 0.002	1290:1314	fixed carbon 4.23 ± 0.002	1290:1314	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	2	3	theme	prognosticating	350:364	arg1	approach					366:373	a prognosticating approach	348:373	a prognosticating approach to tackle many agricultural/forestry residues	348:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	2	3	theme	prognosticating	350:364	arg1	biorefinery					276:286	the sustainable biorefinery	260:286	the sustainable biorefinery of lignocellulosic waste	260:311	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	4	4	theme	lignocellulosic	629:643	arg1	biomass					645:651	lignocellulosic biomass	629:651	lignocellulosic biomass	629:651	Thus the characterization of lignocellulosic biomass is essential to understanding the feedstock's nature, composition and suitability for biofuel production.					
36329067	2	5	theme	waste	307:311	arg1	approach					366:373	a prognosticating approach	348:373	a prognosticating approach to tackle many agricultural/forestry residues	348:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	2	5	theme	waste	307:311	arg1	biorefinery					276:286	the sustainable biorefinery	260:286	the sustainable biorefinery of lignocellulosic waste	260:311	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	9	6	theme	matter	1250:1255	arg1	87.67 ± 0.002					1257:1269	volatile matter 87.67 ± 0.002	1241:1269	volatile matter 87.67 ± 0.002	1241:1269	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	6	theme	matter	1250:1255	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	3	7	theme	major	550:554	arg1	bottlenecks					556:566	the major bottlenecks	546:566	the major bottlenecks in lignocellulosic biorefinery	546:597	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	1	8	theme	promising	180:188	arg1	alternative					190:200	a promising alternative	178:200	a promising alternative to the alarming depletion of fossil fuels	178:242	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	1	8	theme	promising	180:188	arg1	production					102:111	The production	98:111	The production of renewable and sustainable biofuels using inevitable wastes	98:173	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	6	9	theme	pods	924:927	arg1	characterization					901:916	Proximate, ultimate and biochemical characterization	865:916	Proximate, ultimate and biochemical characterization of Pj pods	865:927	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	11	10	theme	lignin	1563:1568	arg1	4.71 ± 0.12					1570:1580	lignin 4.71 ± 0.12	1563:1580	lignin 4.71 ± 0.12	1563:1580	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	2	11	theme	alternative	320:330	arg1	source					337:342	an alternative fuel source	317:342	an alternative fuel source	317:342	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	1	12	theme	alarming	209:216	arg1	depletion					218:226	the alarming depletion	205:226	the alarming depletion of fossil fuels	205:242	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	9	13	theme	fixed	1290:1294	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	13	theme	fixed	1290:1294	arg1	4.23 ± 0.002					1303:1314	fixed carbon 4.23 ± 0.002	1290:1314	fixed carbon 4.23 ± 0.002	1290:1314	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	6	14	theme	calorific	971:979	arg1	values					981:986	thermal behaviour and calorific values	949:986	thermal behaviour and calorific values	949:986	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	11	15	theme	dry	1501:1503	arg1	basis					1505:1509	a dry basis	1499:1509	a dry basis	1499:1509	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	2	16	theme	sustainable	264:274	arg1	approach					366:373	a prognosticating approach	348:373	a prognosticating approach to tackle many agricultural/forestry residues	348:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	2	16	theme	sustainable	264:274	arg1	biorefinery					276:286	the sustainable biorefinery	260:286	the sustainable biorefinery of lignocellulosic waste	260:311	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	1	17	theme	biofuels	142:149	arg1	alternative					190:200	a promising alternative	178:200	a promising alternative to the alarming depletion of fossil fuels	178:242	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	1	17	theme	biofuels	142:149	arg1	production					102:111	The production	98:111	The production of renewable and sustainable biofuels using inevitable wastes	98:173	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	1	18	theme	inevitable	157:166	arg1	wastes					168:173	inevitable wastes	157:173	inevitable wastes	157:173	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	0	19	theme	bioenergy	77:85	arg1	feedstock					87:95	a potential bioenergy feedstock	65:95	a potential bioenergy feedstock	65:95	The comprehensive characterization of Prosopis juliflora pods as a potential bioenergy feedstock.					
36329067	9	20	theme	17.62 kg/MJ	1342:1352	arg1	value					1333:1337	a calorific value	1321:1337	a calorific value of 17.62 kg/MJ	1321:1352	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	12	21	theme	&1H	1736:1738	arg1	NMR					1740:1742	CP/MAS &1H NMR	1729:1742	CP/MAS &1H NMR	1729:1742	The isolated cellulose and hemicellulose were analyzed and confirmed by CP/MAS &1H NMR, FTIR, TG-DSC, SEM, XRD, and TGA.					
36329067	5	22	theme	evergreen	782:790	arg1	feedstock					854:862	an energy feedstock	844:862	an energy feedstock	844:862	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	22	theme	evergreen	782:790	arg1	pods					809:812	evergreen spiny non-edible pods	782:812	evergreen spiny non-edible pods of Prosopis juliflora (Pj)	782:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	10	23	theme	CHNS	1359:1362	arg1	content					1364:1370	The CHNS content	1355:1370	The CHNS content	1355:1370	The CHNS content was (w/w %) carbon 41.77, nitrogen 3.58, sulfur 26.3 and hydrogen 6.55.					
36329067	10	23	theme	CHNS	1359:1362	arg1	carbon					1384:1389	carbon 41.77	1384:1395	carbon 41.77	1384:1395	The CHNS content was (w/w %) carbon 41.77, nitrogen 3.58, sulfur 26.3 and hydrogen 6.55.					
36329067	11	24	theme	analysis	1472:1479	arg1	yields					1481:1486	The biochemical composition analysis yields	1444:1486	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.	1444:1655	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	24	theme	analysis	1472:1479	arg1	w/w					1491:1493	% w/w	1489:1493	% w/w	1489:1493	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	5	25	theme	non-edible	798:807	arg1	feedstock					854:862	an energy feedstock	844:862	an energy feedstock	844:862	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	25	theme	non-edible	798:807	arg1	pods					809:812	evergreen spiny non-edible pods	782:812	evergreen spiny non-edible pods of Prosopis juliflora (Pj)	782:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	2	26	theme	environmental	462:474	arg1	benefits					476:483	environmental benefits	462:483	a circular economy as well as environmental benefits	432:483	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	11	27	theme	biochemical	1448:1458	arg1	analysis					1472:1479	biochemical composition analysis	1448:1479	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.	1444:1655	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	2	28	theme	agricultural/forestry	390:410	arg1	residues					412:419	tackle many agricultural/forestry residues	378:419	tackle many agricultural/forestry residues	378:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	5	29	theme	energy	847:852	arg1	feedstock					854:862	an energy feedstock	844:862	an energy feedstock	844:862	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	29	theme	energy	847:852	arg1	pods					809:812	evergreen spiny non-edible pods	782:812	evergreen spiny non-edible pods of Prosopis juliflora (Pj)	782:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	9	30	contain	contain	1202:1208	arg1	pods					1197:1200	The collected Pj pods	1180:1200	The collected Pj pods	1180:1200	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	30	contain	contain	1202:1208	arg2	0.21 ± 0.002					1276:1287	ash 0.21 ± 0.002	1272:1287	ash 0.21 ± 0.002	1272:1287	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	30	contain	contain	1202:1208	arg2	87.67 ± 0.002					1257:1269	volatile matter 87.67 ± 0.002	1241:1269	volatile matter 87.67 ± 0.002	1241:1269	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	30	contain	contain	1202:1208	arg2	4.23 ± 0.002					1303:1314	fixed carbon 4.23 ± 0.002	1290:1314	fixed carbon 4.23 ± 0.002	1290:1314	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	30	contain	contain	1202:1208	arg2	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	12	31	theme	isolated	1661:1668	arg1	cellulose					1670:1678	cellulose	1670:1678	cellulose	1670:1678	The isolated cellulose and hemicellulose were analyzed and confirmed by CP/MAS &1H NMR, FTIR, TG-DSC, SEM, XRD, and TGA.					
36329067	11	32	theme	hemicellulose	1535:1547	arg1	30.86 ± 0.27					1549:1560	hemicellulose 30.86 ± 0.27	1535:1560	hemicellulose 30.86 ± 0.27	1535:1560	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	3	33	gly	heterogeneity	495:507	arg1	biomass					528:534	lignocellulosic biomass	512:534	lignocellulosic biomass	512:534	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	6	34	theme	Pj	921:922	arg1	pods					924:927	Pj pods	921:927	Pj pods	921:927	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	0	35	theme	Prosopis	38:45	arg1	juliflora					47:55	Prosopis juliflora	38:55	Prosopis juliflora	38:55	The comprehensive characterization of Prosopis juliflora pods as a potential bioenergy feedstock.					
36329067	8	36	theme	potential	1145:1153	arg1	feedstock					1155:1163	a potential feedstock	1143:1163	a potential feedstock for bioenergy	1143:1177	The overall characterization has revealed the Pj pods as a potential feedstock for bioenergy.					
36329067	8	36	theme	potential	1145:1153	arg1	pods					1135:1138	the Pj pods	1128:1138	the Pj pods	1128:1138	The overall characterization has revealed the Pj pods as a potential feedstock for bioenergy.					
36329067	12	37	dep	cellulose	1670:1678	arg1	The					1657:1659	The	1657:1659	The	1657:1659	The isolated cellulose and hemicellulose were analyzed and confirmed by CP/MAS &1H NMR, FTIR, TG-DSC, SEM, XRD, and TGA.					
36329067	13	38	used	used	1861:1864	arg2	biomass					1823:1829	the tested biomass	1812:1829	the tested biomass	1812:1829	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	13	38	used	used	1861:1864	arg2	juliflora					1841:1849	Prosopis juliflora	1832:1849	Prosopis juliflora	1832:1849	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	13	38	used	used	1861:1864	arg2	feedstock					1871:1879	a feedstock	1869:1879	a feedstock in biorefinery for bioenergy	1869:1908	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	1	39	theme	fossil	231:236	arg1	fuels					238:242	fossil fuels	231:242	fossil fuels	231:242	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	11	40	theme	starch	1608:1613	arg1	1.1 ± 0.06					1615:1624	starch 1.1 ± 0.06	1608:1624	starch 1.1 ± 0.06	1608:1624	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	4	41	theme	biomass	645:651	arg1	essential					656:664	essential	656:664	essential	656:664	Thus the characterization of lignocellulosic biomass is essential to understanding the feedstock's nature, composition and suitability for biofuel production.					
36329067	4	41	theme	biomass	645:651	arg1	characterization					609:624	the characterization	605:624	the characterization of lignocellulosic biomass	605:651	Thus the characterization of lignocellulosic biomass is essential to understanding the feedstock's nature, composition and suitability for biofuel production.					
36329067	2	42	theme	tackle	378:383	arg1	residues					412:419	tackle many agricultural/forestry residues	378:419	tackle many agricultural/forestry residues	378:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	3	43	theme	biomass	528:534	arg1	bottlenecks					556:566	the major bottlenecks	546:566	the major bottlenecks in lignocellulosic biorefinery	546:597	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	3	43	theme	biomass	528:534	arg1	one					539:541	one	539:541	one	539:541	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	3	43	theme	biomass	528:534	arg1	heterogeneity					495:507	the heterogeneity	491:507	the heterogeneity of lignocellulosic biomass	491:534	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	6	44	theme	thermal	949:955	arg1	values					981:986	thermal behaviour and calorific values	949:986	thermal behaviour and calorific values	949:986	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	3	45	theme	bottlenecks	556:566	arg1	bottlenecks					556:566	the major bottlenecks	546:566	the major bottlenecks in lignocellulosic biorefinery	546:597	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	3	45	theme	bottlenecks	556:566	arg1	one					539:541	one	539:541	one	539:541	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	3	45	theme	bottlenecks	556:566	arg1	heterogeneity					495:507	the heterogeneity	491:507	the heterogeneity of lignocellulosic biomass	491:534	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	9	46	theme	Pj	1194:1195	arg1	pods					1197:1200	The collected Pj pods	1180:1200	The collected Pj pods	1180:1200	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	13	47	theme	present	1782:1788	arg1	results					1790:1796	The present results	1778:1796	The present results	1778:1796	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	9	48	theme	volatile	1241:1248	arg1	87.67 ± 0.002					1257:1269	volatile matter 87.67 ± 0.002	1241:1269	volatile matter 87.67 ± 0.002	1241:1269	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	48	theme	volatile	1241:1248	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	2	49	theme	lignocellulosic	291:305	arg1	waste					307:311	lignocellulosic waste	291:311	lignocellulosic waste	291:311	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	10	50	dep	carbon	1384:1389	arg1	%					1381:1381	w/w %	1377:1381	w/w %	1377:1381	The CHNS content was (w/w %) carbon 41.77, nitrogen 3.58, sulfur 26.3 and hydrogen 6.55.					
36329067	5	51	theme	juliflora	826:834	arg1	feedstock					854:862	an energy feedstock	844:862	an energy feedstock	844:862	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	51	theme	juliflora	826:834	arg1	pods					809:812	evergreen spiny non-edible pods	782:812	evergreen spiny non-edible pods of Prosopis juliflora (Pj)	782:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	11	52	theme	protein	1583:1589	arg1	11.63 ± 0.12					1591:1602	protein 11.63 ± 0.12	1583:1602	protein 11.63 ± 0.12	1583:1602	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	2	53	theme	fuel	332:335	arg1	source					337:342	an alternative fuel source	317:342	an alternative fuel source	317:342	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	9	54	theme	ash	1272:1274	arg1	0.21 ± 0.002					1276:1287	ash 0.21 ± 0.002	1272:1287	ash 0.21 ± 0.002	1272:1287	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	54	theme	ash	1272:1274	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	3	55	theme	lignocellulosic	571:585	arg1	biorefinery					587:597	lignocellulosic biorefinery	571:597	lignocellulosic biorefinery	571:597	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	5	56	theme	present	763:769	arg1	study					771:775	The present study	759:775	The present study	759:775	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	9	57	theme	carbon	1296:1301	arg1	7.89 ± 0.002					1227:1238	moisture 7.89 ± 0.002	1218:1238	moisture 7.89 ± 0.002	1218:1238	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	57	theme	carbon	1296:1301	arg1	4.23 ± 0.002					1303:1314	fixed carbon 4.23 ± 0.002	1290:1314	fixed carbon 4.23 ± 0.002	1290:1314	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	1	58	theme	renewable	116:124	arg1	biofuels					142:149	renewable and sustainable biofuels	116:149	renewable and sustainable biofuels using inevitable wastes	116:173	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	7	59	theme	reliable	1068:1075	arg1	methods					1077:1083	reliable methods	1068:1083	reliable methods	1068:1083	Cellulose and hemicellulose were isolated and characterized by reliable methods.					
36329067	1	60	theme	sustainable	130:140	arg1	biofuels					142:149	renewable and sustainable biofuels	116:149	renewable and sustainable biofuels using inevitable wastes	116:173	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	11	61	dep	yields	1481:1486	arg1	1.1 ± 0.06					1615:1624	starch 1.1 ± 0.06	1608:1624	starch 1.1 ± 0.06	1608:1624	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	61	dep	yields	1481:1486	arg1	26.6 ± 0.18					1522:1532	cellulose 26.6 ± 0.18	1512:1532	cellulose 26.6 ± 0.18	1512:1532	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	61	dep	yields	1481:1486	arg1	4.71 ± 0.12					1570:1580	lignin 4.71 ± 0.12	1563:1580	lignin 4.71 ± 0.12	1563:1580	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	61	dep	yields	1481:1486	arg1	extractives					1630:1640	extractives 30.56 ± 0.008	1630:1654	extractives 30.56 ± 0.008	1630:1654	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	61	dep	yields	1481:1486	arg1	30.86 ± 0.27					1549:1560	hemicellulose 30.86 ± 0.27	1535:1560	hemicellulose 30.86 ± 0.27	1535:1560	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	61	dep	yields	1481:1486	arg1	11.63 ± 0.12					1591:1602	protein 11.63 ± 0.12	1583:1602	protein 11.63 ± 0.12	1583:1602	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	0	62	theme	potential	67:75	arg1	feedstock					87:95	a potential bioenergy feedstock	65:95	a potential bioenergy feedstock	65:95	The comprehensive characterization of Prosopis juliflora pods as a potential bioenergy feedstock.					
36329067	9	63	theme	calorific	1323:1331	arg1	value					1333:1337	a calorific value	1321:1337	a calorific value of 17.62 kg/MJ	1321:1352	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	64	dep	7.89 ± 0.002	1227:1238	arg1	%					1211:1211	%	1211:1211	% w/w	1211:1215	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	11	65	theme	cellulose	1512:1520	arg1	26.6 ± 0.18					1522:1532	cellulose 26.6 ± 0.18	1512:1532	cellulose 26.6 ± 0.18	1512:1532	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	5	66	theme	Prosopis	817:824	arg1	Pj					837:838	Pj	837:838	Pj	837:838	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	66	theme	Prosopis	817:824	arg1	juliflora					826:834	Prosopis juliflora	817:834	Prosopis juliflora (Pj)	817:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	8	67	theme	overall	1090:1096	arg1	characterization					1098:1113	The overall characterization	1086:1113	The overall characterization	1086:1113	The overall characterization has revealed the Pj pods as a potential feedstock for bioenergy.					
36329067	4	68	theme	biofuel	739:745	arg1	production					747:756	biofuel production	739:756	biofuel production	739:756	Thus the characterization of lignocellulosic biomass is essential to understanding the feedstock's nature, composition and suitability for biofuel production.					
36329067	3	69	from	bottlenecks	556:566	arg1	biorefinery					587:597	lignocellulosic biorefinery	571:597	lignocellulosic biorefinery	571:597	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	13	70	from	feedstock	1871:1879	arg1	biorefinery					1884:1894	biorefinery	1884:1894	biorefinery	1884:1894	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	12	71	theme	CP/MAS	1729:1734	arg1	NMR					1740:1742	CP/MAS &1H NMR	1729:1742	CP/MAS &1H NMR	1729:1742	The isolated cellulose and hemicellulose were analyzed and confirmed by CP/MAS &1H NMR, FTIR, TG-DSC, SEM, XRD, and TGA.					
36329067	11	72	theme	composition	1460:1470	arg1	analysis					1472:1479	biochemical composition analysis	1448:1479	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.	1444:1655	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	5	73	theme	spiny	792:796	arg1	feedstock					854:862	an energy feedstock	844:862	an energy feedstock	844:862	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	5	73	theme	spiny	792:796	arg1	pods					809:812	evergreen spiny non-edible pods	782:812	evergreen spiny non-edible pods of Prosopis juliflora (Pj)	782:839	The present study taps evergreen spiny non-edible pods of Prosopis juliflora (Pj) as an energy feedstock.					
36329067	0	74	theme	comprehensive	4:16	arg1	characterization					18:33	The comprehensive characterization	0:33	The comprehensive characterization of Prosopis juliflora	0:55	The comprehensive characterization of Prosopis juliflora pods as a potential bioenergy feedstock.					
36329067	11	75	theme	%	1489:1489	arg1	yields					1481:1486	The biochemical composition analysis yields	1444:1486	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.	1444:1655	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	11	75	theme	%	1489:1489	arg1	w/w					1491:1493	% w/w	1489:1493	% w/w	1489:1493	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	2	76	theme	many	385:388	arg1	residues					412:419	tackle many agricultural/forestry residues	378:419	tackle many agricultural/forestry residues	378:419	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	13	77	theme	Prosopis	1832:1839	arg1	biomass					1823:1829	the tested biomass	1812:1829	the tested biomass	1812:1829	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	13	77	theme	Prosopis	1832:1839	arg1	juliflora					1841:1849	Prosopis juliflora	1832:1849	Prosopis juliflora	1832:1849	The present results revealed that the tested biomass, Prosopis juliflora, could be used as a feedstock in biorefinery for bioenergy.					
36329067	2	78	theme	circular	434:441	arg1	economy					443:449	a circular economy	432:449	a circular economy as well as environmental benefits	432:483	Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits.					
36329067	0	79	theme	juliflora	47:55	arg1	characterization					18:33	The comprehensive characterization	0:33	The comprehensive characterization of Prosopis juliflora	0:55	The comprehensive characterization of Prosopis juliflora pods as a potential bioenergy feedstock.					
36329067	11	80	from	yields	1481:1486	arg1	basis					1505:1509	a dry basis	1499:1509	a dry basis	1499:1509	The biochemical composition analysis yields (% w/w) on a dry basis; cellulose 26.6 ± 0.18, hemicellulose 30.86 ± 0.27, lignin 4.71 ± 0.12, protein 11.63 ± 0.12 and starch 1.1 ± 0.06 and extractives 30.56 ± 0.008.					
36329067	9	81	dep	%	1211:1211	arg1	w/w					1213:1215	w/w	1213:1215	% w/w	1211:1215	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	9	82	theme	collected	1184:1192	arg1	pods					1197:1200	The collected Pj pods	1180:1200	The collected Pj pods	1180:1200	The collected Pj pods contain (% w/w) moisture 7.89 ± 0.002, volatile matter 87.67 ± 0.002, ash 0.21 ± 0.002, fixed carbon 4.23 ± 0.002 with a calorific value of 17.62 kg/MJ.					
36329067	6	83	theme	biochemical	889:899	arg1	characterization					901:916	Proximate, ultimate and biochemical characterization	865:916	Proximate, ultimate and biochemical characterization of Pj pods	865:927	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	3	84	theme	lignocellulosic	512:526	arg1	biomass					528:534	lignocellulosic biomass	512:534	lignocellulosic biomass	512:534	But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.					
36329067	6	85	theme	ultimate	876:883	arg1	characterization					901:916	Proximate, ultimate and biochemical characterization	865:916	Proximate, ultimate and biochemical characterization of Pj pods	865:927	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
36329067	1	86	theme	fuels	238:242	arg1	depletion					218:226	the alarming depletion	205:226	the alarming depletion of fossil fuels	205:242	The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels.					
36329067	6	87	theme	Proximate	865:873	arg1	characterization					901:916	Proximate, ultimate and biochemical characterization	865:916	Proximate, ultimate and biochemical characterization of Pj pods	865:927	Proximate, ultimate and biochemical characterization of Pj pods were conducted, and thermal behaviour and calorific values were determined.					
37255364	0	0	theme	hybrids	99:105	arg1	mechanics					70:78	mechanics	70:78	mechanics	70:78	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	0	0	theme	hybrids	99:105	arg1	hierarchy					56:64	hierarchy	56:64	hierarchy	56:64	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	7	1	theme	mechanical	1222:1231	arg1	properties					1233:1242	the mechanical properties	1218:1242	the mechanical properties of these composite materials	1218:1271	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	8	2	with	materials	1473:1481	arg1	properties					1508:1517	targeted mechanical properties	1488:1517	targeted mechanical properties for a specific application using a limited selection of building blocks	1488:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	4	3	theme	secondary	771:779	arg1	structure					781:789	secondary structure	771:789	secondary structure	771:789	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	0	4	theme	peptide-polymer	83:97	arg1	hybrids					99:105	peptide-polymer hybrids	83:105	peptide-polymer hybrids	83:105	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	2	5	used	used	375:378	arg2	pathway					391:397	another pathway	383:397	another pathway towards hierarchical tuning via matrix-filler interactions	383:456	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	2	5	used	used	375:378	arg2	addition					320:327	The addition	316:327	The addition of nanofiller with hydrogen bonding sites	316:369	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	1	6	theme	peptide	171:177	arg1	motifs					179:184	peptide motifs	171:184	peptide motifs	171:184	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	2	7	with	addition	320:327	arg1	sites					365:369	hydrogen bonding sites	348:369	hydrogen bonding sites	348:369	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	7	8	theme	CNC	1302:1304	arg1	reinforcement					1306:1318	CNC reinforcement	1302:1318	CNC reinforcement	1302:1318	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	8	9	theme	limited	1554:1560	arg1	selection					1562:1570	a limited selection	1552:1570	a limited selection of building blocks	1552:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	4	10	theme	mechanical	819:828	arg1	properties					830:839	mechanical properties	819:839	mechanical properties	819:839	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	6	11	theme	CNC	1093:1095	arg1	content					1097:1103	CNC content	1093:1103	CNC content	1093:1103	Depending on peptide and CNC content, the Young's modulus varies from 10 to 150 MPa.					
37255364	7	12	theme	reinforcement	1306:1318	arg1	balance					1291:1297	a balance	1289:1297	a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology	1289:1374	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	5	13	theme	peptide	904:910	arg1	matrix					912:917	the peptide matrix	900:917	the peptide matrix	900:917	Interactions between the peptide matrix and CNCs occur in all of the PPU/CNC nanocomposites, preventing α-helical ordering, but promoting inter-molecular hydrogen bonded β-sheet formation.					
37255364	7	14	theme	microphase-separated	1344:1363	arg1	morphology					1365:1374	microphase-separated morphology	1344:1374	microphase-separated morphology	1344:1374	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	3	15	theme	tailored	605:612	arg1	interactions					628:639	tailored matrix-filler interactions	605:639	tailored matrix-filler interactions	605:639	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	3	16	theme	cellulose	524:532	arg1	nanocrystals					534:545	cellulose nanocrystals	524:545	cellulose nanocrystals (CNCs)	524:552	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	3	16	theme	cellulose	524:532	arg1	CNCs					548:551	CNCs	548:551	CNCs	548:551	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	7	17	theme	polymer	1194:1200	arg1	nanocomposites					1202:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	3	18	theme	mechanically-tunable	565:584	arg1	nanocomposites					586:599	mechanically-tunable nanocomposites	565:599	mechanically-tunable nanocomposites	565:599	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	4	19	theme	matrix-filler	737:749	arg1	interactions					751:762	these matrix-filler interactions	731:762	these matrix-filler interactions	731:762	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	1	20	theme	conventional	284:295	arg1	framework					305:313	a conventional polymer framework	282:313	a conventional polymer framework	282:313	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	4	21	theme	peptide	848:854	arg1	nanocomposites					863:876	the peptide hybrid nanocomposites	844:876	the peptide hybrid nanocomposites	844:876	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	6	22	dep	150	1144:1146	arg1	to					1141:1142	to	1141:1142	to	1141:1142	Depending on peptide and CNC content, the Young's modulus varies from 10 to 150 MPa.					
37255364	0	23	theme	peptide-cellulose	11:27	arg1	interactions					29:40	Leveraging peptide-cellulose interactions	0:40	Leveraging peptide-cellulose interactions	0:40	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	7	24	theme	peptidic	1321:1328	arg1	ordering					1330:1337	peptidic ordering	1321:1337	peptidic ordering	1321:1337	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	7	25	theme	conventional	1160:1171	arg1	nanocomposites					1202:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	4	26	from	effect	721:726	arg1	properties					830:839	mechanical properties	819:839	mechanical properties	819:839	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	4	26	from	effect	721:726	arg1	structure					781:789	secondary structure	771:789	secondary structure	771:789	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	4	26	from	effect	721:726	arg1	ordering					805:812	hierarchical ordering	792:812	hierarchical ordering	792:812	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	2	27	theme	hierarchical	407:418	arg1	tuning					420:425	hierarchical tuning	407:425	hierarchical tuning via matrix-filler interactions	407:456	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	0	28	theme	Leveraging	0:9	arg1	interactions					29:40	Leveraging peptide-cellulose interactions	0:40	Leveraging peptide-cellulose interactions	0:40	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	1	29	theme	polymer	297:303	arg1	framework					305:313	a conventional polymer framework	282:313	a conventional polymer framework	282:313	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	4	30	theme	hierarchical	792:803	arg1	ordering					805:812	hierarchical ordering	792:812	hierarchical ordering	792:812	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	2	31	theme	nanofiller	332:341	arg1	addition					320:327	The addition	316:327	The addition of nanofiller with hydrogen bonding sites	316:369	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	2	31	theme	nanofiller	332:341	arg1	pathway					391:397	another pathway	383:397	another pathway towards hierarchical tuning via matrix-filler interactions	383:456	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	4	32	dep	structure	781:789	arg1	the					767:769	the	767:769	the	767:769	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	3	33	theme	peptide-polyurea	473:488	arg1	hybrids					490:496	peptide-polyurea hybrids	473:496	peptide-polyurea hybrids (PPUs)	473:503	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	3	33	theme	peptide-polyurea	473:488	arg1	PPUs					499:502	PPUs	499:502	PPUs	499:502	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	1	34	theme	framework	305:313	arg1	properties					268:277	the mechanical properties	253:277	the mechanical properties of a conventional polymer framework	253:313	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	5	35	theme	α-helical	983:991	arg1	ordering					993:1000	α-helical ordering	983:1000	α-helical ordering	983:1000	Interactions between the peptide matrix and CNCs occur in all of the PPU/CNC nanocomposites, preventing α-helical ordering, but promoting inter-molecular hydrogen bonded β-sheet formation.					
37255364	3	36	theme	matrix-filler	614:626	arg1	interactions					628:639	tailored matrix-filler interactions	605:639	tailored matrix-filler interactions	605:639	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	5	37	theme	bonded	1042:1047	arg1	formation					1057:1065	inter-molecular hydrogen bonded β-sheet formation	1017:1065	inter-molecular hydrogen bonded β-sheet formation	1017:1065	Interactions between the peptide matrix and CNCs occur in all of the PPU/CNC nanocomposites, preventing α-helical ordering, but promoting inter-molecular hydrogen bonded β-sheet formation.					
37255364	4	38	theme	hybrid	856:861	arg1	nanocomposites					863:876	the peptide hybrid nanocomposites	844:876	the peptide hybrid nanocomposites	844:876	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	1	39	theme	spider	120:125	arg1	silk					127:130	spider silk	120:130	spider silk's hierarchical diversity	120:155	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	7	40	theme	cellulose-reinforced	1173:1192	arg1	nanocomposites					1202:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	conventional cellulose-reinforced polymer nanocomposites	1160:1215	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	7	41	theme	composite	1253:1261	arg1	materials					1263:1271	these composite materials	1247:1271	these composite materials	1247:1271	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	1	42	theme	structural	214:223	arg1	arrangement					225:235	structural arrangement	214:235	structural arrangement	214:235	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	7	43	theme	materials	1263:1271	arg1	properties					1233:1242	the mechanical properties	1218:1242	the mechanical properties of these composite materials	1218:1271	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	5	44	theme	PPU/CNC	948:954	arg1	nanocomposites					956:969	the PPU/CNC nanocomposites	944:969	the PPU/CNC nanocomposites	944:969	Interactions between the peptide matrix and CNCs occur in all of the PPU/CNC nanocomposites, preventing α-helical ordering, but promoting inter-molecular hydrogen bonded β-sheet formation.					
37255364	0	45	dep	hierarchy	56:64	arg1	the					52:54	the	52:54	the	52:54	Leveraging peptide-cellulose interactions to tailor the hierarchy and mechanics of peptide-polymer hybrids.					
37255364	2	46	theme	matrix-filler	431:443	arg1	interactions					445:456	matrix-filler interactions	431:456	matrix-filler interactions	431:456	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	3	47	theme	peptide-cellulose	645:661	arg1	interactions					663:674	peptide-cellulose interactions	645:674	peptide-cellulose interactions	645:674	Specifically, peptide-polyurea hybrids (PPUs) were combined with cellulose nanocrystals (CNCs) to develop mechanically-tunable nanocomposites via tailored matrix-filler interactions (or peptide-cellulose interactions).					
37255364	8	48	theme	peptide-cellulose	1418:1434	arg1	interactions					1436:1447	peptide-cellulose interactions	1418:1447	peptide-cellulose interactions	1418:1447	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	8	49	theme	building	1575:1582	arg1	blocks					1584:1589	building blocks	1575:1589	building blocks	1575:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	1	50	theme	hierarchical	134:145	arg1	diversity					147:155	spider silk's hierarchical diversity	120:155	spider silk's hierarchical diversity	120:155	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37255364	5	51	theme	β-sheet	1049:1055	arg1	formation					1057:1065	inter-molecular hydrogen bonded β-sheet formation	1017:1065	inter-molecular hydrogen bonded β-sheet formation	1017:1065	Interactions between the peptide matrix and CNCs occur in all of the PPU/CNC nanocomposites, preventing α-helical ordering, but promoting inter-molecular hydrogen bonded β-sheet formation.					
37255364	8	52	theme	mechanical	1497:1506	arg1	properties					1508:1517	targeted mechanical properties	1488:1517	targeted mechanical properties for a specific application using a limited selection of building blocks	1488:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	8	53	theme	targeted	1488:1495	arg1	properties					1508:1517	targeted mechanical properties	1488:1517	targeted mechanical properties for a specific application using a limited selection of building blocks	1488:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	4	54	theme	nanocomposites	863:876	arg1	properties					830:839	mechanical properties	819:839	mechanical properties	819:839	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	4	54	theme	nanocomposites	863:876	arg1	structure					781:789	secondary structure	771:789	secondary structure	771:789	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	4	54	theme	nanocomposites	863:876	arg1	ordering					805:812	hierarchical ordering	792:812	hierarchical ordering	792:812	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	2	55	theme	hydrogen	348:355	arg1	sites					365:369	hydrogen bonding sites	348:369	hydrogen bonding sites	348:369	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	2	56	theme	bonding	357:363	arg1	sites					365:369	hydrogen bonding sites	348:369	hydrogen bonding sites	348:369	The addition of nanofiller with hydrogen bonding sites was used as another pathway towards hierarchical tuning via matrix-filler interactions.					
37255364	7	57	theme	ordering	1330:1337	arg1	balance					1291:1297	a balance	1289:1297	a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology	1289:1374	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	8	58	theme	specific	1525:1532	arg1	application					1534:1544	a specific application	1523:1544	a specific application using a limited selection of building blocks	1523:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	8	59	theme	blocks	1584:1589	arg1	selection					1562:1570	a limited selection	1552:1570	a limited selection of building blocks	1552:1589	This research highlights that leveraging peptide-cellulose interactions is a strategy to create materials with targeted mechanical properties for a specific application using a limited selection of building blocks.					
37255364	7	60	theme	morphology	1365:1374	arg1	balance					1291:1297	a balance	1289:1297	a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology	1289:1374	Unlike conventional cellulose-reinforced polymer nanocomposites, the mechanical properties of these composite materials are dictated by a balance of CNC reinforcement, peptidic ordering, and microphase-separated morphology.					
37255364	4	61	theme	material	686:693	arg1	platform					695:702	this material platform	681:702	this material platform	681:702	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	4	62	theme	interactions	751:762	arg1	effect					721:726	the effect	717:726	the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites	717:876	In this material platform, we explored the effect of these matrix-filler interactions on the secondary structure, hierarchical ordering, and mechanical properties of the peptide hybrid nanocomposites.					
37255364	1	63	theme	mechanical	257:266	arg1	properties					268:277	the mechanical properties	253:277	the mechanical properties of a conventional polymer framework	253:313	Inspired by spider silk's hierarchical diversity, we leveraged peptide motifs with the capability to tune structural arrangement for controlling the mechanical properties of a conventional polymer framework.					
37014823	0	0	theme	NADES	64:68	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	0	theme	NADES	64:68	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	2	1	from	water	358:362	arg1	insoluble					345:353	insoluble	345:353	insoluble	345:353	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	2	2	from	insoluble	345:353	arg1	lipids					367:372	lipids	367:372	lipids	367:372	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	2	2	from	insoluble	345:353	arg1	water					358:362	water	358:362	water	358:362	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	1	3	theme	solubilization	114:127	arg1	matrix					129:134	a third solubilization matrix	106:134	a third solubilization matrix (besides water and lipids)	106:161	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	9	4	from	matrix	1520:1525	arg1	tract					1545:1549	the intestinal tract	1530:1549	the intestinal tract	1530:1549	The mucous layer would thus constitute a NADES based digestion matrix in the intestinal tract.					
37014823	1	5	theme	natural	194:200	arg1	NADES					226:230	NADES	226:230	NADES	226:230	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	1	5	theme	natural	194:200	arg1	solvents					216:223	natural deep eutectic solvents	194:223	natural deep eutectic solvents (NADES)	194:231	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	5	6	with	glycoproteins	737:749	arg1	sugars					764:769	exposed sugars	756:769	exposed sugars	756:769	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	6	with	glycoproteins	737:749	arg1	acids					796:800	amino acids	790:800	amino acids like proline and threonine	790:827	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	6	with	glycoproteins	737:749	arg1	acids					901:905	organic acids	893:905	organic acids	893:905	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	6	with	glycoproteins	737:749	arg1	sugars					778:783	amino sugars	772:783	amino sugars	772:783	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	6	with	glycoproteins	737:749	arg1	amines					852:857	quaternary amines	841:857	quaternary amines like choline and ethanolamine	841:887	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	7	dep	NADES	724:728	arg1	glycoproteins					737:749	glycoproteins	737:749	glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid	737:932	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	1	8	theme	deep	202:205	arg1	NADES					226:230	NADES	226:230	NADES	226:230	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	1	8	theme	deep	202:205	arg1	solvents					216:223	natural deep eutectic solvents	194:223	natural deep eutectic solvents (NADES)	194:231	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	0	9	theme	based	71:75	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	9	theme	based	71:75	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	2	10	from	lipids	367:372	arg1	insoluble					345:353	insoluble	345:353	insoluble	345:353	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	6	11	theme	intestine	1043:1051	arg1	layer					1024:1028	the mucous layer	1013:1028	the mucous layer of the small intestine where it performs its digestive action	1013:1090	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	3	12	theme	lipid-based	467:477	arg1	matrices					479:486	lipid-based matrices	467:486	lipid-based matrices	467:486	NADES matrices also support enzyme activity, such as amylase, at higher rates than water or lipid-based matrices.					
37014823	1	13	theme	eutectic	207:214	arg1	NADES					226:230	NADES	226:230	NADES	226:230	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	1	13	theme	eutectic	207:214	arg1	solvents					216:223	natural deep eutectic solvents	194:223	natural deep eutectic solvents (NADES)	194:231	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	9	14	theme	based	1504:1508	arg1	matrix					1520:1525	a NADES based digestion matrix	1496:1525	a NADES based digestion matrix in the intestinal tract	1496:1549	The mucous layer would thus constitute a NADES based digestion matrix in the intestinal tract.					
37014823	6	15	theme	small	1037:1041	arg1	intestine					1043:1051	the small intestine	1033:1051	the small intestine where it performs its digestive action	1033:1090	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	2	16	theme	important	298:306	arg1	starch					327:332	starch	327:332	starch	327:332	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	2	16	theme	important	298:306	arg1	molecules					308:316	many biologically important molecules	280:316	many biologically important molecules	280:316	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	8	17	from	layer	1257:1261	arg1	intestines					1276:1285	the small intestines	1266:1285	the small intestines	1266:1285	Hence, we propose that the mucous layer in the small intestines harbors digestive enzymes like amylase, while starch, due to solubility, redistributes from the lumen into the mucous layer where it is subsequently digested by amylase.					
37014823	5	18	theme	amino	790:794	arg1	acids					796:800	amino acids	790:800	amino acids like proline and threonine	790:827	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	3	19	theme	higher	440:445	arg1	rates					447:451	higher rates	440:451	higher rates than water or lipid-based matrices	440:486	NADES matrices also support enzyme activity, such as amylase, at higher rates than water or lipid-based matrices.					
37014823	4	20	theme	starch	566:571	arg1	digestion					573:581	small intestinal starch digestion	549:581	small intestinal starch digestion	549:581	We contemplated if a NADES environment could play a role in small intestinal starch digestion.					
37014823	0	21	theme	digestion	77:85	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	21	theme	digestion	77:85	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	6	22	gly	glycoproteins	992:1004	arg1	glycoproteins					992:1004	glycoproteins	992:1004	glycoproteins	992:1004	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	7	23	from	sites	1131:1135	arg1	amylase					1104:1110	Dislodging amylase	1093:1110	Dislodging amylase from these binding sites	1093:1135	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	4	24	theme	intestinal	555:564	arg1	digestion					573:581	small intestinal starch digestion	549:581	small intestinal starch digestion	549:581	We contemplated if a NADES environment could play a role in small intestinal starch digestion.					
37014823	5	25	gly	glycoproteins	737:749	arg1	glycoproteins					737:749	glycoproteins	737:749	glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid	737:932	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	26	theme	mucous	663:668	arg1	layer					670:674	the secreted mucous layer	650:674	the secreted mucous layer	650:674	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	9	27	theme	digestion	1510:1518	arg1	matrix					1520:1525	a NADES based digestion matrix	1496:1525	a NADES based digestion matrix in the intestinal tract	1496:1549	The mucous layer would thus constitute a NADES based digestion matrix in the intestinal tract.					
37014823	6	28	theme	mucous	1017:1022	arg1	layer					1024:1028	the mucous layer	1013:1028	the mucous layer of the small intestine where it performs its digestive action	1013:1090	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	7	29	theme	digestive	1184:1192	arg1	result					1215:1220	a result	1213:1220	a result	1213:1220	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	7	29	theme	digestive	1184:1192	arg1	problems					1201:1208	digestive health problems	1184:1208	digestive health problems	1184:1208	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	0	30	theme	mucous	18:23	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	30	theme	mucous	18:23	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	6	31	theme	Various	936:942	arg1	studies					944:950	Various studies	936:950	Various studies	936:950	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	8	32	theme	mucous	1250:1255	arg1	layer					1257:1261	the mucous layer	1246:1261	the mucous layer in the small intestines	1246:1285	Hence, we propose that the mucous layer in the small intestines harbors digestive enzymes like amylase, while starch, due to solubility, redistributes from the lumen into the mucous layer where it is subsequently digested by amylase.					
37014823	0	33	theme	intestinal	7:16	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	33	theme	intestinal	7:16	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	8	34	theme	mucous	1398:1403	arg1	layer					1405:1409	the mucous layer	1394:1409	the mucous layer where it is subsequently digested by amylase	1394:1454	Hence, we propose that the mucous layer in the small intestines harbors digestive enzymes like amylase, while starch, due to solubility, redistributes from the lumen into the mucous layer where it is subsequently digested by amylase.					
37014823	5	35	theme	quaternary	841:850	arg1	amines					852:857	quaternary amines	841:857	quaternary amines like choline and ethanolamine	841:887	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	8	36	theme	digestive	1295:1303	arg1	enzymes					1305:1311	digestive enzymes	1295:1311	digestive enzymes like amylase	1295:1324	Hence, we propose that the mucous layer in the small intestines harbors digestive enzymes like amylase, while starch, due to solubility, redistributes from the lumen into the mucous layer where it is subsequently digested by amylase.					
37014823	2	37	theme	Such	234:237	arg1	matrices					239:246	Such matrices	234:246	Such matrices	234:246	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	9	38	theme	intestinal	1534:1543	arg1	tract					1545:1549	the intestinal tract	1530:1549	the intestinal tract	1530:1549	The mucous layer would thus constitute a NADES based digestion matrix in the intestinal tract.					
37014823	4	39	theme	small	549:553	arg1	digestion					573:581	small intestinal starch digestion	549:581	small intestinal starch digestion	549:581	We contemplated if a NADES environment could play a role in small intestinal starch digestion.					
37014823	3	40	theme	NADES	375:379	arg1	matrices					381:388	NADES matrices	375:388	NADES matrices	375:388	NADES matrices also support enzyme activity, such as amylase, at higher rates than water or lipid-based matrices.					
37014823	5	41	theme	chemical	683:690	arg1	composition					692:702	a chemical composition	681:702	a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid)	681:933	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	1	42	dep	proposed	172:179	arg1	composed					182:189	composed	182:189	composed of natural deep eutectic solvents (NADES)	182:231	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	5	43	theme	organic	893:899	arg1	acids					901:905	organic acids	893:905	organic acids	893:905	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	44	theme	secreted	654:661	arg1	layer					670:674	the secreted mucous layer	650:674	the secreted mucous layer	650:674	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	0	45	theme	Deep	41:44	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	45	theme	Deep	41:44	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	7	46	theme	Dislodging	1093:1102	arg1	amylase					1104:1110	Dislodging amylase	1093:1110	Dislodging amylase from these binding sites	1093:1135	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	2	47	theme	many	280:283	arg1	starch					327:332	starch	327:332	starch	327:332	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	2	47	theme	many	280:283	arg1	molecules					308:316	many biologically important molecules	280:316	many biologically important molecules	280:316	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
37014823	0	48	theme	NAtural	33:39	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	48	theme	NAtural	33:39	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	5	49	theme	intestinal	588:597	arg1	layer					606:610	The intestinal mucous layer	584:610	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer)	584:675	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	50	theme	citric	912:917	arg1	acid					929:932	citric and malic acid	912:932	acid	929:932	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	6	51	theme	digestive	1075:1083	arg1	action					1085:1090	its digestive action	1071:1090	its digestive action	1071:1090	Various studies have indeed shown that amylase binds to glycoproteins within the mucous layer of the small intestine where it performs its digestive action.					
37014823	7	52	theme	starch	1145:1150	arg1	digestion					1152:1160	starch digestion	1145:1160	starch digestion	1145:1160	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	7	53	theme	binding	1123:1129	arg1	sites					1131:1135	these binding sites	1117:1135	these binding sites	1117:1135	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	5	54	theme	mucous	599:604	arg1	layer					606:610	The intestinal mucous layer	584:610	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer)	584:675	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	7	55	theme	health	1194:1199	arg1	result					1215:1220	a result	1213:1220	a result	1213:1220	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	7	55	theme	health	1194:1199	arg1	problems					1201:1208	digestive health problems	1184:1208	digestive health problems	1184:1208	Dislodging amylase from these binding sites impedes starch digestion and it may well cause digestive health problems as a result.					
37014823	3	56	theme	enzyme	403:408	arg1	activity					410:417	enzyme activity	403:417	enzyme activity	403:417	NADES matrices also support enzyme activity, such as amylase, at higher rates than water or lipid-based matrices.					
37014823	5	57	theme	malic	923:927	arg1	acid					929:932	citric and malic acid	912:932	acid	929:932	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	58	dep	glycoproteins	737:749	arg1	e.g.					731:734	e.g.	731:734	e.g.	731:734	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	1	59	theme	third	108:112	arg1	matrix					129:134	a third solubilization matrix	106:134	a third solubilization matrix (besides water and lipids)	106:161	In plants, a third solubilization matrix (besides water and lipids) has been proposed, composed of natural deep eutectic solvents (NADES).					
37014823	4	60	theme	NADES	510:514	arg1	environment					516:526	a NADES environment	508:526	a NADES environment	508:526	We contemplated if a NADES environment could play a role in small intestinal starch digestion.					
37014823	0	61	theme	Solvent	55:61	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	61	theme	Solvent	55:61	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	9	62	theme	mucous	1461:1466	arg1	layer					1468:1472	The mucous layer	1457:1472	The mucous layer	1457:1472	The mucous layer would thus constitute a NADES based digestion matrix in the intestinal tract.					
37014823	5	63	theme	amino	772:776	arg1	sugars					778:783	amino sugars	772:783	amino sugars	772:783	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	64	theme	exposed	756:762	arg1	sugars					764:769	exposed sugars	756:769	exposed sugars	756:769	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	0	65	theme	Eutectic	46:53	arg1	layer					25:29	the intestinal mucous layer	3:29	the intestinal mucous layer	3:29	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	0	65	theme	Eutectic	46:53	arg1	matrix					87:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	a NAtural Deep Eutectic Solvent (NADES) based digestion matrix	31:92	Is the intestinal mucous layer a NAtural Deep Eutectic Solvent (NADES) based digestion matrix?					
37014823	5	66	contain	has	677:679	arg1	layer					606:610	The intestinal mucous layer	584:610	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer)	584:675	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	5	66	contain	has	677:679	arg2	composition					692:702	a chemical composition	681:702	a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid)	681:933	The intestinal mucous layer (encompassing both the glycocalyx and the secreted mucous layer) has a chemical composition that fits well with NADES (e.g., glycoproteins with exposed sugars, amino sugars, and amino acids like proline and threonine, as well as quaternary amines like choline and ethanolamine and organic acids like citric and malic acid).					
37014823	8	67	theme	small	1270:1274	arg1	intestines					1276:1285	the small intestines	1266:1285	the small intestines	1266:1285	Hence, we propose that the mucous layer in the small intestines harbors digestive enzymes like amylase, while starch, due to solubility, redistributes from the lumen into the mucous layer where it is subsequently digested by amylase.					
37014823	2	68	theme	molecules	308:316	arg1	solubilization					262:275	the solubilization	258:275	the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids	258:372	Such matrices allow for the solubilization of many biologically important molecules, such as starch, which are insoluble in water or lipids.					
35051499	5	0	theme	rheological	803:813	arg1	behavior					815:822	rheological behavior	803:822	rheological behavior	803:822	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	4	1	theme	homogenization	721:734	arg1	treatment					736:744	homogenization treatment	721:744	homogenization treatment	721:744	The cationic fibers with degrees of substitution (DS) between 0.02 and 0.36, were subjected to homogenization treatment.					
35051499	1	2	theme	energy	274:279	arg1	consumption					281:291	energy consumption	274:291	energy consumption	274:291	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	8	3	theme	materials	1502:1510	arg1	properties					1464:1473	the final properties	1454:1473	the final properties of the cationic cellulosic materials	1454:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	5	4	theme	similar	927:933	arg1	DS					935:936	similar DS	927:936	similar DS	927:936	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	8	5	theme	cellulosic	1491:1500	arg1	materials					1502:1510	the cationic cellulosic materials	1478:1510	the cationic cellulosic materials	1478:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	7	6	theme	longer	1209:1214	arg1	fibrils					1216:1222	longer fibrils	1209:1222	longer fibrils with an average diameter of 1 μm	1209:1255	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	0	7	from	Effect	0:5	arg1	properties					44:53	the properties	40:53	the properties of cationic Eucalyptus	40:76	Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose.					
35051499	3	8	theme	periodate	583:591	arg1	method					575:580	a two-step method	564:580	a two-step method (periodate oxidation + Girard's reagent T)	564:623	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	8	theme	periodate	583:591	arg1	T					622:622	periodate oxidation + Girard's reagent T	583:622	periodate oxidation + Girard's reagent T	583:622	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	6	9	theme	structure	1020:1028	arg1	degradation					991:1001	significant degradation	979:1001	significant degradation of the cellulose structure	979:1028	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	5	10	with	samples	914:920	arg1	DS					935:936	similar DS	927:936	similar DS	927:936	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	7	11	theme	1 μm	1252:1255	arg1	diameter					1240:1247	an average diameter	1229:1247	an average diameter of 1 μm	1229:1255	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	4	12	theme	cationic	630:637	arg1	fibers					639:644	The cationic fibers	626:644	The cationic fibers	626:644	The cationic fibers with degrees of substitution (DS) between 0.02 and 0.36, were subjected to homogenization treatment.					
35051499	5	13	theme	chemical	777:784	arg1	composition					786:796	chemical composition	777:796	chemical composition	777:796	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	7	14	theme	cellulose	1277:1285	arg1	degradation					1287:1297	no significant cellulose degradation	1262:1297	no significant cellulose degradation	1262:1297	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	3	15	with	reaction	502:509	arg1	chloride					549:556	2,3-epoxypropyltrimethylammonium chloride	516:556	2,3-epoxypropyltrimethylammonium chloride	516:556	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	5	16	theme	cationization	888:900	arg1	method					902:907	the cationization method	884:907	the cationization method	884:907	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	5	17	theme	method	902:907	arg1	effect					874:879	the effect	870:879	the effect of the cationization method	870:907	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	5	17	theme	method	902:907	arg1	effect					853:858	the effect	849:858	the effect of DS	849:864	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	6	18	theme	cellulose	1010:1018	arg1	structure					1020:1028	the cellulose structure	1006:1028	the cellulose structure	1006:1028	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	5	19	dep	assess	842:847	arg1	samples					914:920	samples	914:920	samples with similar DS	914:936	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	6	20	theme	0.36	1170:1173	arg1	DS					1164:1165	a DS	1162:1165	a DS of 0.36	1162:1173	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	1	21	theme	past	208:211	arg1	decades					217:223	the past few decades	204:223	the past few decades	204:223	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	7	22	theme	Direct	1176:1181	arg1	cationization					1183:1195	Direct cationization	1176:1195	Direct cationization	1176:1195	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	7	23	theme	average	1232:1238	arg1	diameter					1240:1247	an average diameter	1229:1247	an average diameter of 1 μm	1229:1255	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	7	24	theme	significant	1265:1275	arg1	degradation					1287:1297	no significant cellulose degradation	1262:1297	no significant cellulose degradation	1262:1297	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	1	25	theme	few	213:215	arg1	decades					217:223	the past few decades	204:223	the past few decades	204:223	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	3	26	attach	attached	461:468	arg2	groups					449:454	quaternary ammonium groups	429:454	quaternary ammonium groups	429:454	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	26	attach	attached	461:468	arg3	reaction					502:509	a direct reaction	493:509	a direct reaction with 2,3-epoxypropyltrimethylammonium chloride	493:556	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	26	attach	attached	461:468	arg3	work					423:426	this work	418:426	this work	418:426	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	26	attach	attached	461:468	arg1	fibers					483:488	cellulose fibers	473:488	cellulose fibers	473:488	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	1	27	theme	Micro/nanofibrillated	111:131	arg1	M/NFCs					145:150	M/NFCs	145:150	M/NFCs	145:150	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	1	27	theme	Micro/nanofibrillated	111:131	arg1	celluloses					133:142	Micro/nanofibrillated celluloses	111:142	Micro/nanofibrillated celluloses (M/NFCs)	111:151	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	8	28	from	influence	1413:1421	arg1	properties					1464:1473	the final properties	1454:1473	the final properties of the cationic cellulosic materials	1454:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	0	29	theme	pretreatment	24:35	arg1	Effect					0:5	Effect	0:5	Effect of cationization pretreatment on the properties of cationic Eucalyptus	0:76	Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose.					
35051499	6	30	theme	material	1099:1106	arg1	solubilization					1077:1090	solubilization	1077:1090	solubilization of the material	1077:1106	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	6	30	theme	material	1099:1106	arg1	fibrils					1065:1071	short fibrils	1059:1071	short fibrils	1059:1071	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	2	31	theme	few	332:334	arg1	studies					336:342	few studies	332:342	few studies	332:342	To date, few studies have considered cationization as a pretreatment for their preparation.					
35051499	7	32	from	%	1366:1366	arg1	material					1349:1356	a more cohesive gel-like material	1324:1356	a more cohesive gel-like material (at 1 wt%)	1324:1367	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	6	33	theme	solubilization	1077:1090	arg1	formation					1046:1054	the formation	1042:1054	the formation	1042:1054	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	0	34	theme	cationization	10:22	arg1	pretreatment					24:35	cationization pretreatment	10:35	cationization pretreatment	10:35	Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose.					
35051499	8	35	theme	cationization	1430:1442	arg1	method					1444:1449	the cationization method	1426:1449	the cationization method	1426:1449	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	3	36	theme	reagent	614:620	arg1	method					575:580	a two-step method	564:580	a two-step method (periodate oxidation + Girard's reagent T)	564:623	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	36	theme	reagent	614:620	arg1	T					622:622	periodate oxidation + Girard's reagent T	583:622	periodate oxidation + Girard's reagent T	583:622	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	37	theme	direct	495:500	arg1	reaction					502:509	a direct reaction	493:509	a direct reaction with 2,3-epoxypropyltrimethylammonium chloride	493:556	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	38	theme	ammonium	440:447	arg1	groups					449:454	quaternary ammonium groups	429:454	quaternary ammonium groups	429:454	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	6	39	theme	significant	979:989	arg1	degradation					991:1001	significant degradation	979:1001	significant degradation of the cellulose structure	979:1028	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	6	40	theme	fibrils	1065:1071	arg1	formation					1046:1054	the formation	1042:1054	the formation	1042:1054	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	1	41	theme	various	231:237	arg1	pretreatments					239:251	various pretreatments	231:251	various pretreatments	231:251	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	5	42	theme	morphological	751:763	arg1	properties					765:774	The morphological properties	747:774	The morphological properties	747:774	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	6	43	theme	short	1059:1063	arg1	fibrils					1065:1071	short fibrils	1059:1071	short fibrils	1059:1071	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	8	44	theme	method	1444:1449	arg1	influence					1413:1421	the strong influence	1402:1421	the strong influence of the cationization method on the final properties of the cationic cellulosic materials	1402:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	3	45	theme	2,3-epoxypropyltrimethylammonium	516:547	arg1	chloride					549:556	2,3-epoxypropyltrimethylammonium chloride	516:556	2,3-epoxypropyltrimethylammonium chloride	516:556	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	46	theme	quaternary	429:438	arg1	groups					449:454	quaternary ammonium groups	429:454	quaternary ammonium groups	429:454	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	8	47	theme	final	1458:1462	arg1	properties					1464:1473	the final properties	1454:1473	the final properties of the cationic cellulosic materials	1454:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	7	48	with	fibrils	1216:1222	arg1	diameter					1240:1247	an average diameter	1229:1247	an average diameter of 1 μm	1229:1255	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	7	49	theme	cohesive	1331:1338	arg1	material					1349:1356	a more cohesive gel-like material	1324:1356	a more cohesive gel-like material (at 1 wt%)	1324:1367	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	6	50	theme	complete	1135:1142	arg1	solubilization					1144:1157	almost complete solubilization	1128:1157	almost complete solubilization	1128:1157	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	6	51	theme	two-step	944:951	arg1	cationization					953:965	The two-step cationization	940:965	The two-step cationization	940:965	The two-step cationization resulted in significant degradation of the cellulose structure, leading to the formation of short fibrils and solubilization of the material, ranging from 6% to almost complete solubilization at a DS of 0.36.					
35051499	8	52	theme	strong	1406:1411	arg1	influence					1413:1421	the strong influence	1402:1421	the strong influence of the cationization method on the final properties of the cationic cellulosic materials	1402:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	4	53	with	fibers	639:644	arg1	degrees					651:657	degrees	651:657	degrees of substitution (DS)	651:678	The cationic fibers with degrees of substitution (DS) between 0.02 and 0.36, were subjected to homogenization treatment.					
35051499	1	54	used	used	259:262	arg2	pretreatments					239:251	various pretreatments	231:251	various pretreatments	231:251	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	1	55	theme	research	181:188	arg1	interest					190:197	considerable research interest	168:197	considerable research interest	168:197	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	0	56	theme	Eucalyptus	67:76	arg1	properties					44:53	the properties	40:53	the properties of cationic Eucalyptus	40:76	Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose.					
35051499	7	57	theme	gel-like	1340:1347	arg1	material					1349:1356	a more cohesive gel-like material	1324:1356	a more cohesive gel-like material (at 1 wt%)	1324:1367	Direct cationization resulted in longer fibrils with an average diameter of 1 μm, and no significant cellulose degradation was observed, leading to a more cohesive gel-like material (at 1 wt%).					
35051499	1	58	theme	considerable	168:179	arg1	interest					190:197	considerable research interest	168:197	considerable research interest	168:197	Micro/nanofibrillated celluloses (M/NFCs) have attracted considerable research interest over the past few decades, with various pretreatments being used to reduce energy consumption and/or increase fibrillation.					
35051499	3	59	theme	cellulose	473:481	arg1	fibers					483:488	cellulose fibers	473:488	cellulose fibers	473:488	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	4	60	theme	substitution	662:673	arg1	degrees					651:657	degrees	651:657	degrees of substitution (DS)	651:678	The cationic fibers with degrees of substitution (DS) between 0.02 and 0.36, were subjected to homogenization treatment.					
35051499	0	61	theme	cationic	58:65	arg1	Eucalyptus					67:76	cationic Eucalyptus	58:76	cationic Eucalyptus	58:76	Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose.					
35051499	8	62	theme	cationic	1482:1489	arg1	materials					1502:1510	the cationic cellulosic materials	1478:1510	the cationic cellulosic materials	1478:1510	These observations clearly show the strong influence of the cationization method on the final properties of the cationic cellulosic materials.					
35051499	5	63	theme	DS	863:864	arg1	effect					874:879	the effect	870:879	the effect of the cationization method	870:907	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	5	63	theme	DS	863:864	arg1	effect					853:858	the effect	849:858	the effect of DS	849:864	The morphological properties, chemical composition, and rheological behavior were evaluated to assess the effect of DS and the effect of the cationization method (for samples with similar DS).					
35051499	3	64	theme	two-step	566:573	arg1	method					575:580	a two-step method	564:580	a two-step method (periodate oxidation + Girard's reagent T)	564:623	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35051499	3	64	theme	two-step	566:573	arg1	T					622:622	periodate oxidation + Girard's reagent T	583:622	periodate oxidation + Girard's reagent T	583:622	In this work, quaternary ammonium groups were attached to cellulose fibers by a direct reaction with 2,3-epoxypropyltrimethylammonium chloride or by a two-step method (periodate oxidation + Girard's reagent T).					
35245975	12	0	theme	automated	2109:2117	arg1	system					2119:2124	an automated system	2106:2124	an automated system	2106:2124	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	10	1	theme	decellularization	1769:1785	arg1	platform					1787:1794	the reported open-source automated decellularization platform	1734:1794	the reported open-source automated decellularization platform	1734:1794	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	6	2	theme	effective	1162:1170	arg1	decellularization					1172:1188	effective decellularization	1162:1188	effective decellularization	1162:1188	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	6	3	from	%	1078:1078	arg1	content					1106:1112	DNA content	1102:1112	DNA content	1102:1112	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	3	4	theme	work	586:589	arg1	aim					567:569	The aim	563:569	The aim of the current work	563:589	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	11	5	theme	tissue	1974:1979	arg1	engineering					1981:1991	tissue engineering	1974:1991	tissue engineering	1974:1991	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	11	6	theme	user	2082:2085	arg1	error					2087:2091	user error	2082:2091	user error	2082:2091	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	1	7	theme	treatments	200:209	arg1	application					169:179	the application	165:179	the application of many sequential treatments by an operator	165:224	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	10	8	theme	decellularized	1847:1860	arg1	tissues					1862:1868	decellularized tissues	1847:1868	decellularized tissues	1847:1868	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	9	9	theme	Decellularized	1486:1499	arg1	DCC					1512:1514	DCC	1512:1514	DCC	1512:1514	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	9	9	theme	Decellularized	1486:1499	arg1	cartilage					1501:1509	Decellularized cartilage	1486:1509	Decellularized cartilage (DCC)	1486:1515	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	12	10	theme	due	2168:2170	arg1	groups					2161:2166	many research groups	2147:2166	many research groups due to cost and complexity	2147:2193	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	9	11	theme	collagen	1583:1590	arg1	content					1592:1598	collagen content	1583:1598	collagen content	1583:1598	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	8	12	theme	decellularization	1459:1475	arg1	process					1477:1483	the automated decellularization process	1445:1483	the automated decellularization process	1445:1483	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	11	13	theme	extracellular	1913:1925	arg1	ECM					1935:1937	ECM	1935:1937	ECM	1935:1937	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	11	13	theme	extracellular	1913:1925	arg1	matrix					1927:1932	Impact statement Decellularized extracellular matrix	1881:1932	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	3	14	theme	open-source	626:636	arg1	system					666:671	a full open-source automated decellularization system	619:671	a full open-source automated decellularization system to be available for others to adopt	619:707	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	15	15	theme	applications	2604:2615	arg1	research					2549:2556	further research	2541:2556	further research of ECM-based materials and potential clinical applications	2541:2615	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	11	16	theme	Decellularized	1898:1911	arg1	ECM					1935:1937	ECM	1935:1937	ECM	1935:1937	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	11	16	theme	Decellularized	1898:1911	arg1	matrix					1927:1932	Impact statement Decellularized extracellular matrix	1881:1932	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	4	17	theme	low-cost	759:766	arg1	apparatus					744:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	4	17	theme	low-cost	759:766	arg1	device					777:782	a low-cost (<$2000) device	757:782	a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein	757:897	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	11	18	theme	statement	1888:1896	arg1	ECM					1935:1937	ECM	1935:1937	ECM	1935:1937	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	11	18	theme	statement	1888:1896	arg1	matrix					1927:1932	Impact statement Decellularized extracellular matrix	1881:1932	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	15	19	theme	potential	2585:2593	arg1	applications					2604:2615	potential clinical applications	2585:2615	potential clinical applications	2585:2615	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	4	20	theme	<	769:769	arg1	$					770:770	<$2000	769:774	<$2000	769:774	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	14	21	theme	decellularized	2435:2448	arg1	tissues					2450:2456	these decellularized tissues	2429:2456	these decellularized tissues	2429:2456	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	5	22	used	used	943:946	arg2	device					932:937	The automated decellularization device	900:937	The automated decellularization device	900:937	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	15	23	theme	materials	2571:2579	arg1	research					2549:2556	further research	2541:2556	further research of ECM-based materials and potential clinical applications	2541:2615	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	9	24	theme	%	1534:1534	arg1	decrease					1536:1543	a 34% decrease	1530:1543	a 34% decrease in GAG content	1530:1558	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	12	25	theme	research	2152:2159	arg1	groups					2161:2166	many research groups	2147:2166	many research groups due to cost and complexity	2147:2193	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	4	26	theme	decellularization	726:742	arg1	apparatus					744:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	4	26	theme	decellularization	726:742	arg1	device					777:782	a low-cost (<$2000) device	757:782	a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein	757:897	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	0	27	theme	Matrix	79:84	arg1	Retention					86:94	High Extracellular Matrix Retention	60:94	High Extracellular Matrix Retention	60:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	15	28	theme	further	2541:2547	arg1	research					2549:2556	further research	2541:2556	further research of ECM-based materials and potential clinical applications	2541:2615	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	3	29	theme	decellularization	648:664	arg1	system					666:671	a full open-source automated decellularization system	619:671	a full open-source automated decellularization system to be available for others to adopt	619:707	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	14	30	theme	compositional	2401:2413	arg1	properties					2415:2424	the native-like compositional properties	2385:2424	the native-like compositional properties of these decellularized tissues	2385:2456	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	8	31	with	decellularization	1385:1401	arg1	tissue					1417:1422	meniscus tissue	1408:1422	meniscus tissue	1408:1422	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	1	32	theme	many	184:187	arg1	treatments					200:209	many sequential treatments	184:209	many sequential treatments	184:209	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	2	33	theme	decellularization	297:313	arg1	devices					315:321	automated decellularization devices	287:321	automated decellularization devices	287:321	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	2	34	theme	decellularization	444:460	arg1	devices					462:468	previous automated decellularization devices	425:468	previous automated decellularization devices	425:468	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	1	35	theme	Manual	97:102	arg1	decellularization					111:127	Manual tissue decellularization	97:127	Manual tissue decellularization	97:127	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	1	35	theme	Manual	97:102	arg1	process					143:149	an onerous process	132:149	an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability	132:278	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	14	36	theme	musculoskeletal	2343:2357	arg1	tissues					2359:2365	porcine musculoskeletal tissues	2335:2365	porcine musculoskeletal tissues	2335:2365	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	10	37	theme	native-like	1666:1676	arg1	tissues					1693:1699	native-like decellularized tissues	1666:1699	native-like decellularized tissues	1666:1699	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	0	38	theme	Automated	0:8	arg1	Decellularization					10:26	Automated Decellularization	0:26	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention	0:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	5	39	theme	hyaline	965:971	arg1	cartilage					973:981	hyaline cartilage	965:981	hyaline cartilage	965:981	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	4	40	theme	decellularization	826:842	arg1	protocols					844:852	decellularization protocols	826:852	decellularization protocols	826:852	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	10	41	theme	adoptable	1810:1818	arg1	platform					1820:1827	an adoptable platform	1807:1827	an adoptable platform for production of decellularized tissues by others	1807:1878	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	8	42	theme	meniscus	1408:1415	arg1	tissue					1417:1422	meniscus tissue	1408:1422	meniscus tissue	1408:1422	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	2	43	theme	automated	434:442	arg1	devices					462:468	previous automated decellularization devices	425:468	previous automated decellularization devices	425:468	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	0	44	theme	Tissues	47:53	arg1	Decellularization					10:26	Automated Decellularization	0:26	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention	0:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	13	45	theme	automated	2249:2257	arg1	decellularization					2259:2275	automated decellularization	2249:2275	automated decellularization	2249:2275	In this article, a low-cost open-source platform for automated decellularization is presented.					
35245975	7	46	theme	other	1284:1288	arg1	proteins					1290:1297	other proteins	1284:1297	other proteins	1284:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	6	47	from	reduction	1089:1097	arg1	content					1106:1112	DNA content	1102:1112	DNA content	1102:1112	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	10	48	theme	automated	1759:1767	arg1	platform					1787:1794	the reported open-source automated decellularization platform	1734:1794	the reported open-source automated decellularization platform	1734:1794	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	0	49	theme	High	60:63	arg1	Retention					86:94	High Extracellular Matrix Retention	60:94	High Extracellular Matrix Retention	60:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	6	50	theme	DNA	1102:1104	arg1	content					1106:1112	DNA content	1102:1112	DNA content	1102:1112	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	10	51	theme	reported	1738:1745	arg1	platform					1787:1794	the reported open-source automated decellularization platform	1734:1794	the reported open-source automated decellularization platform	1734:1794	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	13	52	theme	low-cost	2215:2222	arg1	platform					2236:2243	a low-cost open-source platform	2213:2243	a low-cost open-source platform for automated decellularization	2213:2275	In this article, a low-cost open-source platform for automated decellularization is presented.					
35245975	12	53	theme	system	2119:2124	arg1	barrier					2135:2141	a barrier	2133:2141	a barrier for many research groups due to cost and complexity	2133:2193	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	12	53	theme	system	2119:2124	arg1	Adoption					2094:2101	Adoption	2094:2101	Adoption of an automated system	2094:2124	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	6	54	theme	tendon	1044:1049	arg1	tissue					1051:1056	tendon tissue	1044:1056	tendon tissue	1044:1056	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	8	55	theme	automated	1449:1457	arg1	process					1477:1483	the automated decellularization process	1445:1483	the automated decellularization process	1445:1483	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	1	56	theme	user	246:249	arg1	error					251:255	user error	246:255	user error	246:255	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	6	57	theme	96	1085:1086	arg1	%					1087:1087	%	1087:1087	%	1087:1087	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	7	58	theme	glycosaminoglycans	1243:1260	arg1	retentions					1229:1238	High retentions	1224:1238	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins	1224:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	6	59	from	%	1073:1073	arg1	content					1106:1112	DNA content	1102:1112	DNA content	1102:1112	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	3	60	theme	current	578:584	arg1	work					586:589	the current work	574:589	the current work	574:589	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	9	61	from	decrease	1536:1543	arg1	content					1552:1558	GAG content	1548:1558	GAG content	1548:1558	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	9	62	theme	GAG	1548:1550	arg1	content					1552:1558	GAG content	1548:1558	GAG content	1548:1558	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	2	63	theme	automated	287:295	arg1	devices					315:321	automated decellularization devices	287:321	automated decellularization devices	287:321	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	1	64	theme	sequential	189:198	arg1	treatments					200:209	many sequential treatments	184:209	many sequential treatments	184:209	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	10	65	theme	tissues	1862:1868	arg1	production					1833:1842	production	1833:1842	production of decellularized tissues by others	1833:1878	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	4	66	theme	example	863:869	arg1	list					878:881	an example parts' list	860:881	an example parts' list provided herein	860:897	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	11	67	theme	Impact	1881:1886	arg1	ECM					1935:1937	ECM	1935:1937	ECM	1935:1937	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	11	67	theme	Impact	1881:1886	arg1	matrix					1927:1932	Impact statement Decellularized extracellular matrix	1881:1932	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	2	68	theme	open-source	402:412	arg1	platforms					414:422	open-source platforms	402:422	open-source platforms	402:422	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	5	69	theme	decellularization	914:930	arg1	device					932:937	The automated decellularization device	900:937	The automated decellularization device	900:937	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	11	70	theme	-based	1939:1944	arg1	materials					1946:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	3	71	theme	full	621:624	arg1	system					666:671	a full open-source automated decellularization system	619:671	a full open-source automated decellularization system to be available for others to adopt	619:707	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	10	72	theme	current	1634:1640	arg1	study					1642:1646	The current study	1630:1646	The current study	1630:1646	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	11	73	theme	matrix	1927:1932	arg1	materials					1946:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials	1881:1954	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	15	74	theme	decellularized	2482:2495	arg1	tissue					2497:2502	decellularized tissue	2482:2502	decellularized tissue	2482:2502	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	1	75	theme	onerous	135:141	arg1	decellularization					111:127	Manual tissue decellularization	97:127	Manual tissue decellularization	97:127	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	1	75	theme	onerous	135:141	arg1	process					143:149	an onerous process	132:149	an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability	132:278	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	14	76	theme	tissues	2450:2456	arg1	properties					2415:2424	the native-like compositional properties	2385:2424	the native-like compositional properties of these decellularized tissues	2385:2456	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	8	77	with	consistent	1429:1438	arg1	process					1477:1483	the automated decellularization process	1445:1483	the automated decellularization process	1445:1483	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	15	78	theme	clinical	2595:2602	arg1	applications					2604:2615	potential clinical applications	2585:2615	potential clinical applications	2585:2615	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	9	79	theme	34	1532:1533	arg1	%					1534:1534	%	1534:1534	%	1534:1534	Decellularized cartilage (DCC) demonstrated a 34% decrease in GAG content, while the protein and collagen content did not significantly change.					
35245975	12	80	theme	many	2147:2150	arg1	groups					2161:2166	many research groups	2147:2166	many research groups due to cost and complexity	2147:2193	Adoption of an automated system may be a barrier for many research groups due to cost and complexity.					
35245975	7	81	theme	High	1224:1227	arg1	retentions					1229:1238	High retentions	1224:1238	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins	1224:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	7	82	located	observed	1304:1311	arg2	retentions					1229:1238	High retentions	1224:1238	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins	1224:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	7	82	located	observed	1304:1311	arg1	tendon					1329:1334	tendon	1329:1334	tendon	1329:1334	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	7	82	located	observed	1304:1311	arg1	meniscus					1316:1323	meniscus	1316:1323	meniscus	1316:1323	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	3	83	theme	automated	638:646	arg1	system					666:671	a full open-source automated decellularization system	619:671	a full open-source automated decellularization system to be available for others to adopt	619:707	The aim of the current work was to develop and validate a full open-source automated decellularization system to be available for others to adopt.					
35245975	4	84	theme	open-source	714:724	arg1	apparatus					744:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus	710:752	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	4	84	theme	open-source	714:724	arg1	device					777:782	a low-cost (<$2000) device	757:782	a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein	757:897	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	15	85	theme	ECM-based	2561:2569	arg1	materials					2571:2579	ECM-based materials	2561:2579	ECM-based materials	2561:2579	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	5	86	theme	automated	904:912	arg1	device					932:937	The automated decellularization device	900:937	The automated decellularization device	900:937	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	14	87	theme	native-like	2389:2399	arg1	properties					2415:2424	the native-like compositional properties	2385:2424	the native-like compositional properties of these decellularized tissues	2385:2456	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	5	88	theme	knee	984:987	arg1	meniscus					989:996	knee meniscus	984:996	knee meniscus	984:996	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	8	89	with	Results	1365:1371	arg1	decellularization					1385:1401	manual decellularization	1378:1401	manual decellularization with meniscus tissue	1378:1422	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	6	90	dep	demonstrated	1058:1069	arg1	confirmed					1190:1198	confirmed	1190:1198	confirmed visually via histology	1190:1221	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	10	91	theme	decellularized	1678:1691	arg1	tissues					1693:1699	native-like decellularized tissues	1666:1699	native-like decellularized tissues	1666:1699	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	15	92	theme	automated	2510:2518	arg1	manner					2520:2525	an automated manner	2507:2525	an automated manner	2507:2525	The ability to produce decellularized tissue in an automated manner is useful for further research of ECM-based materials and potential clinical applications.					
35245975	1	93	theme	tissue	104:109	arg1	decellularization					111:127	Manual tissue decellularization	97:127	Manual tissue decellularization	97:127	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	1	93	theme	tissue	104:109	arg1	process					143:149	an onerous process	132:149	an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability	132:278	Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability.					
35245975	14	94	theme	porcine	2335:2341	arg1	tissues					2359:2365	porcine musculoskeletal tissues	2335:2365	porcine musculoskeletal tissues	2335:2365	This method is validated by decellularizing porcine musculoskeletal tissues and demonstrating the native-like compositional properties of these decellularized tissues.					
35245975	0	95	theme	Musculoskeletal	31:45	arg1	Tissues					47:53	Musculoskeletal Tissues	31:53	Musculoskeletal Tissues	31:53	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	4	96	dep	low-cost	759:766	arg1	$					770:770	<$2000	769:774	<$2000	769:774	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	7	97	theme	proteins	1290:1297	arg1	retentions					1229:1238	High retentions	1224:1238	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins	1224:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	8	98	theme	manual	1378:1383	arg1	decellularization					1385:1401	manual decellularization	1378:1401	manual decellularization with meniscus tissue	1378:1422	Results with manual decellularization with meniscus tissue were consistent with the automated decellularization process.					
35245975	11	99	theme	materials	2018:2026	arg1	production					1998:2007	production	1998:2007	production of these materials	1998:2026	Impact statement Decellularized extracellular matrix (ECM)-based materials are appealing for tissue engineering, but production of these materials is historically time-intensive, tedious, and prone to user error.					
35245975	2	100	theme	software	503:510	arg1	components					512:521	hardware or software components	491:521	hardware or software components that are closed-source and proprietary	491:560	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	2	101	theme	previous	425:432	arg1	devices					462:468	previous automated decellularization devices	425:468	previous automated decellularization devices	425:468	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	0	102	theme	Extracellular	65:77	arg1	Retention					86:94	High Extracellular Matrix Retention	60:94	High Extracellular Matrix Retention	60:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	7	103	theme	collagen	1270:1277	arg1	retentions					1229:1238	High retentions	1224:1238	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins	1224:1297	High retentions of glycosaminoglycans (GAGs), collagen, and other proteins were observed in meniscus and tendon following decellularization.					
35245975	2	104	theme	hardware	491:498	arg1	components					512:521	hardware or software components	491:521	hardware or software components that are closed-source and proprietary	491:560	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
35245975	4	105	theme	protocols	844:852	arg1	array					817:821	an array	814:821	an array of decellularization protocols, with an example parts' list provided herein	814:897	The open-source decellularization apparatus is a low-cost (<$2000) device that may easily be adapted to an array of decellularization protocols, with an example parts' list provided herein.					
35245975	0	106	with	Decellularization	10:26	arg1	Retention					86:94	High Extracellular Matrix Retention	60:94	High Extracellular Matrix Retention	60:94	Automated Decellularization of Musculoskeletal Tissues with High Extracellular Matrix Retention.					
35245975	10	107	theme	open-source	1747:1757	arg1	platform					1787:1794	the reported open-source automated decellularization platform	1734:1794	the reported open-source automated decellularization platform	1734:1794	The current study demonstrated that native-like decellularized tissues were produced reproducibly using the reported open-source automated decellularization platform, providing an adoptable platform for production of decellularized tissues by others.					
35245975	5	108	theme	tendon	1003:1008	arg1	tissues					1010:1016	tendon tissues	1003:1016	tendon tissues	1003:1016	The automated decellularization device was used to decellularize hyaline cartilage, knee meniscus, and tendon tissues.					
35245975	13	109	theme	open-source	2224:2234	arg1	platform					2236:2243	a low-cost open-source platform	2213:2243	a low-cost open-source platform for automated decellularization	2213:2275	In this article, a low-cost open-source platform for automated decellularization is presented.					
35245975	6	110	theme	%	1087:1087	arg1	reduction					1089:1097	96% reduction	1085:1097	96% reduction in DNA content after decellularization	1085:1136	Cartilage, meniscus, and tendon tissue demonstrated 97%, 99%, and 96% reduction in DNA content after decellularization, respectively, and with effective decellularization confirmed visually via histology.					
35245975	2	111	theme	recent	382:387	arg1	years					389:393	recent years	382:393	recent years	382:393	While automated decellularization devices have been previously reported, with advances being made in recent years toward open-source platforms, previous automated decellularization devices have been reliant on hardware or software components that are closed-source and proprietary.					
36434956	6	0	theme	intestinal	1063:1072	arg1	integrity					1082:1090	intestinal barrier integrity	1063:1090	intestinal barrier integrity	1063:1090	HFD impaired intestinal barrier integrity while improved due to EP.					
36434956	8	1	theme	improved	1637:1644	arg1	profiles					1656:1663	improved metabolic profiles	1637:1663	improved metabolic profiles	1637:1663	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	3	2	theme	control	675:681	arg1	diet					683:686	a control diet	673:686	a control diet	673:686	C57BL/6 mice were fed a control diet or a HFD with or without 5% EP for 12 weeks.					
36434956	7	3	theme	short-chain	1214:1224	arg1	acid					1232:1235	the increased short-chain fatty acid	1200:1235	the increased short-chain fatty acid	1200:1235	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	4	4	theme	barrier	803:809	arg1	integrity					811:819	intestinal barrier integrity	792:819	intestinal barrier integrity	792:819	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	9	5	theme	gut	1942:1944	arg1	composition					1957:1967	gut microbiota composition	1942:1967	gut microbiota composition	1942:1967	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	0	6	theme	Polysaccharide-rich	0:18	arg1	fractions					20:28	Polysaccharide-rich fractions	0:28	Polysaccharide-rich fractions from Enteromorpha prolifera	0:56	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	9	7	theme	composition	1957:1967	arg1	modulation					1928:1937	modulation	1928:1937	modulation of gut microbiota composition and related metabolites	1928:1991	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	10	8	theme	mechanistic	2012:2022	arg1	understanding					2024:2036	mechanistic understanding	2012:2036	mechanistic understanding of the anti-obesity and metabolic improving effects of EP	2012:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	4	9	theme	metabolites	871:881	arg1	involvement					837:847	the involvement	833:847	the involvement of gut microbiota and metabolites	833:881	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	4	9	theme	metabolites	871:881	arg1	Factors					733:739	Factors	733:739	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity	733:819	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	9	10	theme	related	1973:1979	arg1	metabolites					1981:1991	related metabolites	1973:1991	related metabolites	1973:1991	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	3	11	theme	5	713:713	arg1	%					714:714	%	714:714	%	714:714	C57BL/6 mice were fed a control diet or a HFD with or without 5% EP for 12 weeks.					
36434956	1	12	theme	EP	400:401	arg1	effect					390:395	this alleviative effect	373:395	this alleviative effect of EP	373:401	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	7	13	theme	barrier-protective	1342:1359	arg1	muciniphila					1373:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	10	14	theme	anti-obesity	2045:2056	arg1	effects					2082:2088	the anti-obesity and metabolic improving effects	2041:2088	the anti-obesity and metabolic improving effects of EP	2041:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	1	15	theme	gut	406:408	arg1	microbiota					410:419	gut microbiota	406:419	gut microbiota	406:419	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	4	16	theme	microbiota	856:865	arg1	involvement					837:847	the involvement	833:847	the involvement of gut microbiota and metabolites	833:881	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	4	16	theme	microbiota	856:865	arg1	Factors					733:739	Factors	733:739	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity	733:819	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	10	17	theme	effects	2082:2088	arg1	understanding					2024:2036	mechanistic understanding	2012:2036	mechanistic understanding of the anti-obesity and metabolic improving effects of EP	2012:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	1	18	from	benefits	254:261	arg1	management					270:279	the management	266:279	the management of obesity and associated metabolic diseases	266:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	5	19	theme	lipopolysaccharides	1023:1041	arg1	resistance					970:979	mitigated insulin resistance	952:979	mitigated insulin resistance	952:979	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	5	19	theme	lipopolysaccharides	1023:1041	arg1	steatosis					990:998	hepatic steatosis	982:998	hepatic steatosis	982:998	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	5	19	theme	lipopolysaccharides	1023:1041	arg1	adiposity					938:946	HFD-induced adiposity	926:946	HFD-induced adiposity	926:946	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	5	19	theme	lipopolysaccharides	1023:1041	arg1	elevation					1004:1012	elevation	1004:1012	elevation of serum lipopolysaccharides (LPS)	1004:1047	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	10	20	theme	metabolic	2062:2070	arg1	effects					2082:2088	the anti-obesity and metabolic improving effects	2041:2088	the anti-obesity and metabolic improving effects of EP	2041:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	7	21	theme	increased	1204:1212	arg1	acid					1232:1235	the increased short-chain fatty acid	1200:1235	the increased short-chain fatty acid	1200:1235	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	9	22	theme	metabolic	1778:1786	arg1	disorders					1788:1796	HFD-induced metabolic disorders	1766:1796	HFD-induced metabolic disorders	1766:1796	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	2	23	theme	high-fat	575:582	arg1	diet					584:587	high-fat diet	575:587	high-fat diet (HFD)	575:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	2	23	theme	high-fat	575:582	arg1	HFD					590:592	HFD	590:592	HFD	590:592	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	0	24	theme	barrier	92:98	arg1	integrity					100:108	gut barrier integrity	88:108	gut barrier integrity	88:108	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	2	25	theme	barrier	543:549	arg1	disruption					551:560	intestinal barrier disruption	532:560	intestinal barrier disruption in mice with high-fat diet (HFD)	532:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	10	26	theme	EP	2093:2094	arg1	effects					2082:2088	the anti-obesity and metabolic improving effects	2041:2088	the anti-obesity and metabolic improving effects of EP	2041:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	2	27	with	metabolism	507:516	arg1	modulation					621:630	modulation	621:630	modulation of gut microbiota	621:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	5	28	theme	HFD-induced	926:936	arg1	adiposity					938:946	HFD-induced adiposity	926:946	HFD-induced adiposity	926:946	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	2	29	theme	gut	635:637	arg1	microbiota					639:648	gut microbiota	635:648	gut microbiota	635:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	0	30	theme	diet-induced	122:133	arg1	mice					141:144	high-fat diet-induced obese mice	113:144	high-fat diet-induced obese mice linking to modulation of gut microbiota	113:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	9	31	theme	gut	1824:1826	arg1	integrity					1836:1844	gut barrier integrity	1824:1844	gut barrier integrity	1824:1844	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	0	32	from	prolifera	48:56	arg1	fractions					20:28	Polysaccharide-rich fractions	0:28	Polysaccharide-rich fractions from Enteromorpha prolifera	0:56	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	7	33	theme	HFD-induced	1158:1168	arg1	dysbiosis					1174:1182	HFD-induced gut dysbiosis	1158:1182	HFD-induced gut dysbiosis	1158:1182	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	1	34	theme	associated	296:305	arg1	diseases					317:324	associated metabolic diseases	296:324	associated metabolic diseases	296:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	9	35	theme	integrity	1836:1844	arg1	restoration					1809:1819	restoration	1809:1819	restoration of gut barrier integrity	1809:1844	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	9	35	theme	integrity	1836:1844	arg1	lowering					1850:1857	lowering	1850:1857	lowering of circulating endotoxin	1850:1882	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	1	36	theme	diseases	317:324	arg1	management					270:279	the management	266:279	the management of obesity and associated metabolic diseases	266:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	2	37	theme	EP	485:486	arg1	effects					474:480	the effects	470:480	the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota	470:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	3	38	theme	C57BL/6	651:657	arg1	mice					659:662	C57BL/6 mice	651:662	C57BL/6 mice	651:662	C57BL/6 mice were fed a control diet or a HFD with or without 5% EP for 12 weeks.					
36434956	4	39	theme	insulin	770:776	arg1	signaling					778:786	insulin signaling	770:786	insulin signaling	770:786	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	7	40	dep	Desulfovibrionaceae	1435:1453	arg1	e.g.					1429:1432	e.g.	1429:1432	e.g.	1429:1432	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	9	41	theme	circulating	1862:1872	arg1	endotoxin					1874:1882	circulating endotoxin	1862:1882	circulating endotoxin	1862:1882	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	2	42	from	association	604:614	arg1	mice					565:568	mice	565:568	mice with high-fat diet (HFD)	565:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	9	43	theme	HFD-induced	1766:1776	arg1	disorders					1788:1796	HFD-induced metabolic disorders	1766:1796	HFD-induced metabolic disorders	1766:1796	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	0	44	theme	hepatic	66:72	arg1	steatosis					74:82	hepatic steatosis	66:82	hepatic steatosis	66:82	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	7	45	theme	SCFA	1511:1514	arg1	content					1516:1522	intestinal SCFA content	1500:1522	intestinal SCFA content	1500:1522	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	7	46	dep	Alloprevotella	1300:1313	arg1	e.g.					1264:1267	e.g.	1264:1267	e.g.	1264:1267	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	8	47	theme	dominant	1578:1585	arg1	genera					1597:1602	dominant bacterial genera	1578:1602	dominant bacterial genera	1578:1602	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	2	48	with	disruption	551:560	arg1	modulation					621:630	modulation	621:630	modulation of gut microbiota	621:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	1	49	theme	important	244:252	arg1	benefits					254:261	important benefits	244:261	important benefits in the management of obesity and associated metabolic diseases	244:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	5	50	theme	insulin	962:968	arg1	resistance					970:979	mitigated insulin resistance	952:979	mitigated insulin resistance	952:979	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	8	51	theme	genera	1597:1602	arg1	change					1568:1573	The change	1564:1573	The change of dominant bacterial genera	1564:1602	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	2	52	with	mice	565:568	arg1	diet					584:587	high-fat diet	575:587	high-fat diet (HFD)	575:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	2	52	with	mice	565:568	arg1	HFD					590:592	HFD	590:592	HFD	590:592	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	6	53	theme	barrier	1074:1080	arg1	integrity					1082:1090	intestinal barrier integrity	1063:1090	intestinal barrier integrity	1063:1090	HFD impaired intestinal barrier integrity while improved due to EP.					
36434956	7	54	from	content	1516:1522	arg1	level					1557:1561	circulating LPS level	1541:1561	circulating LPS level	1541:1561	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	7	55	theme	fatty	1226:1230	arg1	acid					1232:1235	the increased short-chain fatty acid	1200:1235	the increased short-chain fatty acid	1200:1235	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	1	56	theme	obesity	284:290	arg1	management					270:279	the management	266:279	the management of obesity and associated metabolic diseases	266:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	7	57	from	reduction	1528:1536	arg1	level					1557:1561	circulating LPS level	1541:1561	circulating LPS level	1541:1561	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	8	58	theme	metabolic	1646:1654	arg1	profiles					1656:1663	improved metabolic profiles	1637:1663	improved metabolic profiles	1637:1663	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	4	59	theme	intestinal	792:801	arg1	integrity					811:819	intestinal barrier integrity	792:819	intestinal barrier integrity	792:819	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	9	60	theme	microbiota	1946:1955	arg1	composition					1957:1967	gut microbiota composition	1942:1967	gut microbiota composition	1942:1967	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	1	61	theme	Enteromorpha	208:219	arg1	EP					232:233	EP	232:233	EP	232:233	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	1	61	theme	Enteromorpha	208:219	arg1	prolifera					221:229	Enteromorpha prolifera	208:229	Enteromorpha prolifera (EP)	208:234	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	7	62	theme	endotoxin-producing	1399:1417	arg1	bacteria					1419:1426	endotoxin-producing bacteria	1399:1426	endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila)	1399:1468	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	2	63	with	association	604:614	arg1	modulation					621:630	modulation	621:630	modulation of gut microbiota	621:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	0	64	from	integrity	100:108	arg1	mice					141:144	high-fat diet-induced obese mice	113:144	high-fat diet-induced obese mice linking to modulation of gut microbiota	113:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	9	65	theme	metabolites	1981:1991	arg1	modulation					1928:1937	modulation	1928:1937	modulation of gut microbiota composition and related metabolites	1928:1991	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	3	66	theme	%	714:714	arg1	EP					716:717	5% EP	713:717	5% EP	713:717	C57BL/6 mice were fed a control diet or a HFD with or without 5% EP for 12 weeks.					
36434956	2	67	from	metabolism	507:516	arg1	mice					565:568	mice	565:568	mice with high-fat diet (HFD)	565:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	7	68	theme	Akkermansia	1361:1371	arg1	muciniphila					1373:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	0	69	theme	gut	171:173	arg1	microbiota					175:184	gut microbiota	171:184	gut microbiota	171:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	7	70	from	enrichment	1486:1495	arg1	reduction					1528:1536	reduction	1528:1536	reduction in circulating LPS level	1528:1561	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	7	70	from	enrichment	1486:1495	arg1	content					1516:1522	intestinal SCFA content	1500:1522	intestinal SCFA content	1500:1522	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	7	71	theme	gut	1338:1340	arg1	muciniphila					1373:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	gut barrier-protective Akkermansia muciniphila	1338:1383	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	5	72	theme	serum	1017:1021	arg1	lipopolysaccharides					1023:1041	serum lipopolysaccharides	1017:1041	serum lipopolysaccharides (LPS)	1017:1047	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	5	72	theme	serum	1017:1021	arg1	LPS					1044:1046	LPS	1044:1046	LPS	1044:1046	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	4	73	theme	gut	852:854	arg1	microbiota					856:865	gut microbiota	852:865	gut microbiota	852:865	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	10	74	theme	improving	2072:2080	arg1	effects					2082:2088	the anti-obesity and metabolic improving effects	2041:2088	the anti-obesity and metabolic improving effects of EP	2041:2094	These data deepen mechanistic understanding of the anti-obesity and metabolic improving effects of EP.					
36434956	0	75	theme	gut	88:90	arg1	integrity					100:108	gut barrier integrity	88:108	gut barrier integrity	88:108	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	1	76	from	prolifera	221:229	arg1	Polysaccharides					187:201	Polysaccharides	187:201	Polysaccharides from Enteromorpha prolifera (EP)	187:234	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	2	77	theme	lipid	501:505	arg1	metabolism					507:516	lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota	501:648	metabolism	507:516	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	1	78	theme	underlying	344:353	arg1	mechanism					355:363	the underlying mechanism	340:363	the underlying mechanism linking this alleviative effect of EP to gut microbiota	340:419	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	0	79	theme	high-fat	113:120	arg1	mice					141:144	high-fat diet-induced obese mice	113:144	high-fat diet-induced obese mice linking to modulation of gut microbiota	113:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	0	80	theme	microbiota	175:184	arg1	modulation					157:166	modulation	157:166	modulation of gut microbiota	157:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	7	81	theme	LPS	1553:1555	arg1	level					1557:1561	circulating LPS level	1541:1561	circulating LPS level	1541:1561	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	2	82	theme	intestinal	532:541	arg1	disruption					551:560	intestinal barrier disruption	532:560	intestinal barrier disruption in mice with high-fat diet (HFD)	532:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	0	83	from	steatosis	74:82	arg1	mice					141:144	high-fat diet-induced obese mice	113:144	high-fat diet-induced obese mice linking to modulation of gut microbiota	113:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	2	84	theme	microbiota	639:648	arg1	modulation					621:630	modulation	621:630	modulation of gut microbiota	621:648	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	0	85	theme	obese	135:139	arg1	mice					141:144	high-fat diet-induced obese mice	113:144	high-fat diet-induced obese mice linking to modulation of gut microbiota	113:184	Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.					
36434956	1	86	theme	alleviative	378:388	arg1	effect					390:395	this alleviative effect	373:395	this alleviative effect of EP	373:401	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	7	87	dep	-producing	1243:1252	arg1	acid					1232:1235	the increased short-chain fatty acid	1200:1235	the increased short-chain fatty acid	1200:1235	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	2	88	from	disruption	551:560	arg1	mice					565:568	mice	565:568	mice with high-fat diet (HFD)	565:593	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	7	89	theme	gut	1170:1172	arg1	dysbiosis					1174:1182	HFD-induced gut dysbiosis	1158:1182	HFD-induced gut dysbiosis	1158:1182	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	9	90	theme	barrier	1828:1834	arg1	integrity					1836:1844	gut barrier integrity	1824:1844	gut barrier integrity	1824:1844	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	7	91	theme	EP	1128:1129	arg1	administration					1131:1144	EP administration	1128:1144	EP administration	1128:1144	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	1	92	theme	metabolic	307:315	arg1	diseases					317:324	associated metabolic diseases	296:324	associated metabolic diseases	296:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	5	93	theme	EP	899:900	arg1	supplementation					902:916	EP supplementation	899:916	EP supplementation	899:916	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	7	94	theme	circulating	1541:1551	arg1	level					1557:1561	circulating LPS level	1541:1561	circulating LPS level	1541:1561	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	5	95	theme	hepatic	982:988	arg1	steatosis					990:998	hepatic steatosis	982:998	hepatic steatosis	982:998	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	7	96	theme	-producing	1243:1252	arg1	bacteria					1254:1261	the increased short-chain fatty acid (SCFA)-producing bacteria	1200:1261	the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus)	1200:1332	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	9	97	theme	endotoxin	1874:1882	arg1	restoration					1809:1819	restoration	1809:1819	restoration of gut barrier integrity	1809:1844	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	9	97	theme	endotoxin	1874:1882	arg1	lowering					1850:1857	lowering	1850:1857	lowering of circulating endotoxin	1850:1882	In conclusion, our results indicate that EP can attenuate HFD-induced metabolic disorders along with restoration of gut barrier integrity and lowering of circulating endotoxin, and these improvements are associated with modulation of gut microbiota composition and related metabolites.					
36434956	8	98	theme	bacterial	1587:1595	arg1	genera					1597:1602	dominant bacterial genera	1578:1602	dominant bacterial genera	1578:1602	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	1	99	contain	possess	236:242	arg1	Polysaccharides					187:201	Polysaccharides	187:201	Polysaccharides from Enteromorpha prolifera (EP)	187:234	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	1	99	contain	possess	236:242	arg2	benefits					254:261	important benefits	244:261	important benefits in the management of obesity and associated metabolic diseases	244:324	Polysaccharides from Enteromorpha prolifera (EP) possess important benefits in the management of obesity and associated metabolic diseases, but to date, the underlying mechanism linking this alleviative effect of EP to gut microbiota remains obscure.					
36434956	8	100	theme	intestinal	1669:1678	arg1	permeability					1680:1691	intestinal permeability	1669:1691	intestinal permeability induced by EP	1669:1705	The change of dominant bacterial genera is significantly correlated with improved metabolic profiles and intestinal permeability induced by EP.					
36434956	2	101	dep	metabolism	507:516	arg1	disorders					518:526	disorders	518:526	disorders	518:526	This study aimed to investigate the effects of EP in improving lipid metabolism disorders and intestinal barrier disruption in mice with high-fat diet (HFD), and its association with modulation of gut microbiota.					
36434956	5	102	theme	mitigated	952:960	arg1	resistance					970:979	mitigated insulin resistance	952:979	mitigated insulin resistance	952:979	EP supplementation reduced HFD-induced adiposity and mitigated insulin resistance, hepatic steatosis and elevation of serum lipopolysaccharides (LPS).					
36434956	4	103	theme	related	741:747	arg1	Factors					733:739	Factors	733:739	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity	733:819	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
36434956	7	104	theme	intestinal	1500:1509	arg1	content					1516:1522	intestinal SCFA content	1500:1522	intestinal SCFA content	1500:1522	Moreover, EP administration ameliorated HFD-induced gut dysbiosis, as revealed by the increased short-chain fatty acid (SCFA)-producing bacteria (e.g., Bacteroides, Parabacteroides, Alloprevotella, and Ruminococcus) and gut barrier-protective Akkermansia muciniphila and decreased endotoxin-producing bacteria (e.g., Desulfovibrionaceae and Bilophila), accompanied by enrichment in intestinal SCFA content and reduction in circulating LPS level.					
36434956	4	105	theme	lipid	752:756	arg1	metabolism					758:767	lipid metabolism	752:767	lipid metabolism	752:767	Factors related to lipid metabolism, insulin signaling and intestinal barrier integrity, as well as the involvement of gut microbiota and metabolites, were measured.					
35137630	10	0	from	defects	1523:1529	arg1	trachea					1538:1544	trachea	1538:1544	trachea	1538:1544	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	10	0	from	defects	1523:1529	arg1	tissues					1556:1562	other tissues	1550:1562	other tissues	1550:1562	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	13	1	theme	engineered	1944:1953	arg1	sheets					1965:1970	the engineered cartilage sheets	1940:1970	the engineered cartilage sheets	1940:1970	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	15	2	theme	cartilage	2175:2183	arg1	biomaterials					2211:2222	biomaterials	2211:2222	biomaterials for personalized regenerative medicine	2211:2261	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	15	2	theme	cartilage	2175:2183	arg1	sheets					2185:2190	The cartilage sheets	2171:2190	The cartilage sheets	2171:2190	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	11	3	theme	promising	1628:1636	arg1	engineering					1611:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	11	3	theme	promising	1628:1636	arg1	approach					1638:1645	a promising approach	1626:1645	a promising approach to generate biological substitutes	1626:1680	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	14	4	dep	trachea	2115:2121	arg1	the					2111:2113	the	2111:2113	the	2111:2113	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	3	5	theme	cell	275:278	arg1	infiltration					280:291	The chondrocyte cell infiltration	259:291	The chondrocyte cell infiltration activity	259:300	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	13	6	theme	tracheal	1919:1926	arg1	implants					1928:1935	tracheal implants	1919:1935	tracheal implants of the engineered cartilage sheets	1919:1970	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	15	7	theme	cartilage	2314:2322	arg1	sheets					2324:2329	cartilage sheets	2314:2329	cartilage sheets	2314:2329	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	14	8	theme	tissue-engineered	2017:2033	arg1	sheets					2045:2050	the tissue-engineered cartilage sheets	2013:2050	the tissue-engineered cartilage sheets	2013:2050	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	14	9	theme	other	2127:2131	arg1	tissues					2133:2139	other tissues	2127:2139	other tissues	2127:2139	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	7	10	theme	collagen	903:910	arg1	macromolecules					912:925	type II collagen macromolecules	895:925	type II collagen macromolecules	895:925	Cartilage-related sulfated glycosaminoglycans and type II collagen macromolecules were stably expressed in the tracheal implants.					
35137630	9	11	theme	airway	1202:1207	arg1	stenosis					1209:1216	airway stenosis	1202:1216	airway stenosis	1202:1216	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	9	12	from	candidate	1377:1385	arg1	study					1423:1427	this study	1418:1427	this study	1418:1427	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	12	13	theme	tracheal	1723:1730	arg1	prosthesis					1732:1741	tracheal prosthesis	1723:1741	tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model	1723:1815	We aimed to develop cartilage sheets as tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model.					
35137630	4	14	theme	cartilage-related	473:489	arg1	genes					491:495	cartilage-related genes	473:495	cartilage-related genes	473:495	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	15	15	theme	pore	2300:2303	arg1	sizes					2305:2309	pore sizes	2300:2309	pore sizes	2300:2309	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	9	16	theme	scaffolded	1335:1344	arg1	candidate					1377:1385	an optimal candidate	1366:1385	an optimal candidate for tracheal reconstruction	1366:1413	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	9	16	theme	scaffolded	1335:1344	arg1	sheet					1356:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	5	17	theme	thicker	624:630	arg1	sheets					642:647	The thicker cartilage sheets	620:647	The thicker cartilage sheets	620:647	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	3	18	theme	poly-caprolactone	318:334	arg1	scaffolds					342:350	poly-caprolactone sheet scaffolds	318:350	poly-caprolactone sheet scaffolds with various thicknesses and pore sizes	318:390	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	10	19	theme	therapy	1482:1488	arg1	sheets					1449:1454	cartilage sheets	1439:1454	cartilage sheets	1439:1454	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	10	19	theme	therapy	1482:1488	arg1	candidate					1490:1498	a reconstructive therapy candidate	1465:1498	a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage	1465:1584	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	11	20	theme	statement	1594:1602	arg1	engineering					1611:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	11	20	theme	statement	1594:1602	arg1	approach					1638:1645	a promising approach	1626:1645	a promising approach to generate biological substitutes	1626:1680	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	6	21	theme	different	731:739	arg1	sheets					751:756	Two different cartilage sheets	727:756	Two different cartilage sheets	727:756	Two different cartilage sheets were orthotopically implanted into a trachea in a rabbit model for 2, 4, and 16 weeks.					
35137630	12	22	theme	animal	1804:1809	arg1	model					1811:1815	the animal model	1800:1815	the animal model	1800:1815	We aimed to develop cartilage sheets as tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model.					
35137630	3	23	theme	various	357:363	arg1	thicknesses					365:375	various thicknesses	357:375	various thicknesses	357:375	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	0	24	theme	Animal	78:83	arg1	Model					85:89	an Orthotopic Animal Model	64:89	an Orthotopic Animal Model	64:89	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	10	25	theme	reconstructive	1467:1480	arg1	sheets					1449:1454	cartilage sheets	1439:1454	cartilage sheets	1439:1454	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	10	25	theme	reconstructive	1467:1480	arg1	candidate					1490:1498	a reconstructive therapy candidate	1465:1498	a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage	1465:1584	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	9	26	theme	tracheal	1391:1398	arg1	reconstruction					1400:1413	tracheal reconstruction	1391:1413	tracheal reconstruction	1391:1413	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	14	27	theme	cartilage	2153:2161	arg1	tissue					2163:2168	cartilage tissue	2153:2168	cartilage tissue	2153:2168	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	12	28	theme	regional	1778:1785	arg1	repairing					1787:1795	regional repairing	1778:1795	regional repairing	1778:1795	We aimed to develop cartilage sheets as tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model.					
35137630	8	29	theme	time-dependent	1150:1163	arg1	manner					1165:1170	a time-dependent manner	1148:1170	a time-dependent manner	1148:1170	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	3	30	theme	top	419:421	arg1	surface					423:429	the top surface	415:429	the top surface of the sheet scaffolds	415:452	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	4	31	theme	glycosaminoglycans	526:543	arg1	expression					459:468	The expression	455:468	The expression of cartilage-related genes	455:495	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	4	31	theme	glycosaminoglycans	526:543	arg1	accumulation					501:512	accumulation	501:512	accumulation of sulfated glycosaminoglycans	501:543	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	0	32	theme	Tracheal	0:7	arg1	Reconstruction					9:22	Tracheal Reconstruction	0:22	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.	0:90	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	7	33	theme	type	895:898	arg1	collagen					903:910	type II collagen	895:910	type II collagen macromolecules	895:925	Cartilage-related sulfated glycosaminoglycans and type II collagen macromolecules were stably expressed in the tracheal implants.					
35137630	5	34	theme	stronger	661:668	arg1	properties					681:690	stronger mechanical properties	661:690	stronger mechanical properties	661:690	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	1	35	theme	Tracheal	92:99	arg1	reconstruction					101:114	Tracheal reconstruction	92:114	Tracheal reconstruction	92:114	Tracheal reconstruction remains challenged in clinical.					
35137630	8	36	theme	invasive	988:995	arg1	migration					997:1005	the invasive migration	984:1005	the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants	984:1129	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	15	37	dep	dimensions	2273:2282	arg1	the					2269:2271	the	2269:2271	the	2269:2271	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	13	38	theme	sheets	1965:1970	arg1	implants					1928:1935	tracheal implants	1919:1935	tracheal implants of the engineered cartilage sheets	1919:1970	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	14	39	theme	trachea	2115:2121	arg1	reconstruction					2093:2106	the reconstruction	2089:2106	the reconstruction of the trachea and other tissues composed of cartilage tissue	2089:2168	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	3	40	theme	sheet	438:442	arg1	scaffolds					444:452	the sheet scaffolds	434:452	the sheet scaffolds	434:452	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	0	41	theme	Scaffolded	33:42	arg1	Sheets					54:59	the Scaffolded Cartilage Sheets	29:59	the Scaffolded Cartilage Sheets	29:59	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	7	42	theme	Cartilage-related	845:861	arg1	glycosaminoglycans					872:889	Cartilage-related sulfated glycosaminoglycans	845:889	Cartilage-related sulfated glycosaminoglycans	845:889	Cartilage-related sulfated glycosaminoglycans and type II collagen macromolecules were stably expressed in the tracheal implants.					
35137630	8	43	theme	tissue	1018:1023	arg1	migration					997:1005	the invasive migration	984:1005	the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants	984:1129	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	2	44	theme	scaffolded	170:179	arg1	sheets					191:196	scaffolded cartilage sheets	170:196	scaffolded cartilage sheets	170:196	We aimed to fabricate scaffolded cartilage sheets with rigid and elastic supports for tracheal reconstruction.					
35137630	10	45	dep	trachea	1538:1544	arg1	the					1534:1536	the	1534:1536	the	1534:1536	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	9	46	dep	week	1176:1179	arg1	postimplantation					1184:1199	postimplantation	1184:1199	week 16 postimplantation	1176:1199	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	4	47	theme	chondrogenic	596:607	arg1	induction					609:617	chondrogenic induction	596:617	chondrogenic induction	596:617	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	9	48	theme	sheet	1248:1252	arg1	implants					1254:1261	the thicker sheet implants	1236:1261	the thicker sheet implants	1236:1261	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	15	49	theme	regenerative	2241:2252	arg1	medicine					2254:2261	personalized regenerative medicine	2228:2261	personalized regenerative medicine	2228:2261	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	8	50	theme	fibers	1050:1055	arg1	migration					997:1005	the invasive migration	984:1005	the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants	984:1129	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	2	51	dep	rigid	203:207	arg1	supports					221:228	supports	221:228	supports for tracheal reconstruction	221:256	We aimed to fabricate scaffolded cartilage sheets with rigid and elastic supports for tracheal reconstruction.					
35137630	8	52	theme	cartilage	1062:1070	arg1	implants					1072:1079	cartilage implants	1062:1079	cartilage implants	1062:1079	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	11	53	dep	biological	1659:1668	arg1	substitutes					1670:1680	substitutes	1670:1680	substitutes	1670:1680	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	10	54	theme	cartilage	1439:1447	arg1	sheets					1449:1454	cartilage sheets	1439:1454	cartilage sheets	1439:1454	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	10	54	theme	cartilage	1439:1447	arg1	candidate					1490:1498	a reconstructive therapy candidate	1465:1498	a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage	1465:1584	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	9	55	theme	thinner	1276:1282	arg1	implants					1284:1291	the thinner implants	1272:1291	the thinner implants	1272:1291	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	8	56	theme	peripheral	1089:1098	arg1	space					1100:1104	the peripheral space	1085:1104	the peripheral space surrounding the implants	1085:1129	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	5	57	theme	cartilage	709:717	arg1	sheets					719:724	the thinner cartilage sheets	697:724	the thinner cartilage sheets	697:724	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	7	58	theme	tracheal	956:963	arg1	implants					965:972	the tracheal implants	952:972	the tracheal implants	952:972	Cartilage-related sulfated glycosaminoglycans and type II collagen macromolecules were stably expressed in the tracheal implants.					
35137630	3	59	theme	infiltration	280:291	arg1	activity					293:300	The chondrocyte cell infiltration activity	259:300	The chondrocyte cell infiltration activity	259:300	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	13	60	theme	reepithelialization	1868:1886	arg1	dynamics					1856:1863	the dynamics	1852:1863	the dynamics of reepithelialization	1852:1886	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	13	60	theme	reepithelialization	1868:1886	arg1	formation					1822:1830	The formation	1818:1830	The formation of microvessels	1818:1846	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	14	61	theme	cartilage	2035:2043	arg1	sheets					2045:2050	the tissue-engineered cartilage sheets	2013:2050	the tissue-engineered cartilage sheets	2013:2050	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	4	62	theme	cell-scaffold	566:578	arg1	composites					580:589	the cell-scaffold composites	562:589	the cell-scaffold composites	562:589	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	3	63	theme	chondrocyte	263:273	arg1	infiltration					280:291	The chondrocyte cell infiltration	259:291	The chondrocyte cell infiltration activity	259:300	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	9	64	theme	thinner	1314:1320	arg1	candidate					1377:1385	an optimal candidate	1366:1385	an optimal candidate for tracheal reconstruction	1366:1413	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	9	64	theme	thinner	1314:1320	arg1	sheet					1356:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	0	65	with	Reconstruction	9:22	arg1	Sheets					54:59	the Scaffolded Cartilage Sheets	29:59	the Scaffolded Cartilage Sheets	29:59	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	4	66	theme	genes	491:495	arg1	expression					459:468	The expression	455:468	The expression of cartilage-related genes	455:495	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	4	66	theme	genes	491:495	arg1	accumulation					501:512	accumulation	501:512	accumulation of sulfated glycosaminoglycans	501:543	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	14	67	dep	substitutes	2066:2076	arg1	applied					2078:2084	applied	2078:2084	substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue	2066:2168	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	13	68	from	weeks	1910:1914	arg1	implants					1928:1935	tracheal implants	1919:1935	tracheal implants of the engineered cartilage sheets	1919:1970	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	2	69	theme	tracheal	234:241	arg1	reconstruction					243:256	tracheal reconstruction	234:256	tracheal reconstruction	234:256	We aimed to fabricate scaffolded cartilage sheets with rigid and elastic supports for tracheal reconstruction.					
35137630	12	70	theme	cartilage	1703:1711	arg1	sheets					1713:1718	cartilage sheets	1703:1718	cartilage sheets	1703:1718	We aimed to develop cartilage sheets as tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model.					
35137630	11	71	theme	Impact	1587:1592	arg1	engineering					1611:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	11	71	theme	Impact	1587:1592	arg1	approach					1638:1645	a promising approach	1626:1645	a promising approach to generate biological substitutes	1626:1680	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	9	72	theme	cartilage	1346:1354	arg1	candidate					1377:1385	an optimal candidate	1366:1385	an optimal candidate for tracheal reconstruction	1366:1413	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	9	72	theme	cartilage	1346:1354	arg1	sheet					1356:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	5	73	theme	cartilage	632:640	arg1	sheets					642:647	The thicker cartilage sheets	620:647	The thicker cartilage sheets	620:647	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	3	74	theme	sheet	336:340	arg1	scaffolds					342:350	poly-caprolactone sheet scaffolds	318:350	poly-caprolactone sheet scaffolds with various thicknesses and pore sizes	318:390	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	6	75	theme	cartilage	741:749	arg1	sheets					751:756	Two different cartilage sheets	727:756	Two different cartilage sheets	727:756	Two different cartilage sheets were orthotopically implanted into a trachea in a rabbit model for 2, 4, and 16 weeks.					
35137630	0	76	theme	Orthotopic	67:76	arg1	Model					85:89	an Orthotopic Animal Model	64:89	an Orthotopic Animal Model	64:89	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	3	77	theme	pore	381:384	arg1	sizes					386:390	pore sizes	381:390	pore sizes	381:390	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	9	78	theme	optimal	1369:1375	arg1	candidate					1377:1385	an optimal candidate	1366:1385	an optimal candidate for tracheal reconstruction	1366:1413	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	9	78	theme	optimal	1369:1375	arg1	sheet					1356:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	the thinner (1 mm thick) scaffolded cartilage sheet	1310:1360	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	15	79	theme	sheets	2324:2329	arg1	sizes					2305:2309	pore sizes	2300:2309	pore sizes	2300:2309	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	15	79	theme	sheets	2324:2329	arg1	thickness					2285:2293	thickness	2285:2293	thickness	2285:2293	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	15	79	theme	sheets	2324:2329	arg1	dimensions					2273:2282	dimensions	2273:2282	dimensions	2273:2282	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	9	80	dep	thinner	1314:1320	arg1	thick					1328:1332	thick	1328:1332	thick	1328:1332	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	0	81	from	Reconstruction	9:22	arg1	Model					85:89	an Orthotopic Animal Model	64:89	an Orthotopic Animal Model	64:89	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	11	82	theme	Tissue	1604:1609	arg1	engineering					1611:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering	1587:1621	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	11	82	theme	Tissue	1604:1609	arg1	approach					1638:1645	a promising approach	1626:1645	a promising approach to generate biological substitutes	1626:1680	Impact statement Tissue engineering is a promising approach to generate biological substitutes.					
35137630	4	83	theme	sulfated	517:524	arg1	glycosaminoglycans					526:543	sulfated glycosaminoglycans	517:543	sulfated glycosaminoglycans	517:543	The expression of cartilage-related genes and accumulation of sulfated glycosaminoglycans were elevated in the cell-scaffold composites upon chondrogenic induction.					
35137630	13	84	theme	microvessels	1835:1846	arg1	dynamics					1856:1863	the dynamics	1852:1863	the dynamics of reepithelialization	1852:1886	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	13	84	theme	microvessels	1835:1846	arg1	formation					1822:1830	The formation	1818:1830	The formation of microvessels	1818:1846	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	6	85	theme	rabbit	808:813	arg1	model					815:819	a rabbit model	806:819	a rabbit model for 2, 4, and 16 weeks	806:842	Two different cartilage sheets were orthotopically implanted into a trachea in a rabbit model for 2, 4, and 16 weeks.					
35137630	5	86	theme	thinner	701:707	arg1	sheets					719:724	the thinner cartilage sheets	697:724	the thinner cartilage sheets	697:724	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	14	87	theme	tissues	2133:2139	arg1	reconstruction					2093:2106	the reconstruction	2089:2106	the reconstruction of the trachea and other tissues composed of cartilage tissue	2089:2168	In this study, it was demonstrated that the tissue-engineered cartilage sheets are potential substitutes applied in the reconstruction of the trachea and other tissues composed of cartilage tissue.					
35137630	3	88	with	scaffolds	342:350	arg1	thicknesses					365:375	various thicknesses	357:375	various thicknesses	357:375	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	3	88	with	scaffolds	342:350	arg1	sizes					386:390	pore sizes	381:390	pore sizes	381:390	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	10	89	theme	other	1550:1554	arg1	tissues					1556:1562	other tissues	1550:1562	other tissues	1550:1562	Finally, cartilage sheets could be a reconstructive therapy candidate applied to reconstruct defects in the trachea and other tissues composed of cartilage.					
35137630	13	90	theme	cartilage	1955:1963	arg1	sheets					1965:1970	the engineered cartilage sheets	1940:1970	the engineered cartilage sheets	1940:1970	The formation of microvessels and the dynamics of reepithelialization were monitored for 16 weeks in tracheal implants of the engineered cartilage sheets.					
35137630	5	91	theme	mechanical	670:679	arg1	properties					681:690	stronger mechanical properties	661:690	stronger mechanical properties	661:690	The thicker cartilage sheets represented stronger mechanical properties than the thinner cartilage sheets.					
35137630	0	92	theme	Cartilage	44:52	arg1	Sheets					54:59	the Scaffolded Cartilage Sheets	29:59	the Scaffolded Cartilage Sheets	29:59	Tracheal Reconstruction with the Scaffolded Cartilage Sheets in an Orthotopic Animal Model.					
35137630	12	93	theme	tracheal	1751:1758	arg1	reconstruction					1760:1773	tracheal reconstruction	1751:1773	tracheal reconstruction	1751:1773	We aimed to develop cartilage sheets as tracheal prosthesis used in tracheal reconstruction or regional repairing in the animal model.					
35137630	3	94	theme	scaffolds	444:452	arg1	surface					423:429	the top surface	415:429	the top surface of the sheet scaffolds	415:452	The chondrocyte cell infiltration activity was examined in poly-caprolactone sheet scaffolds with various thicknesses and pore sizes after seeding cells on the top surface of the sheet scaffolds.					
35137630	2	95	theme	cartilage	181:189	arg1	sheets					191:196	scaffolded cartilage sheets	170:196	scaffolded cartilage sheets	170:196	We aimed to fabricate scaffolded cartilage sheets with rigid and elastic supports for tracheal reconstruction.					
35137630	7	96	theme	sulfated	863:870	arg1	glycosaminoglycans					872:889	Cartilage-related sulfated glycosaminoglycans	845:889	Cartilage-related sulfated glycosaminoglycans	845:889	Cartilage-related sulfated glycosaminoglycans and type II collagen macromolecules were stably expressed in the tracheal implants.					
35137630	8	97	theme	fibrous	1010:1016	arg1	tissue					1018:1023	fibrous tissue	1010:1023	fibrous tissue	1010:1023	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	9	98	theme	thicker	1240:1246	arg1	implants					1254:1261	the thicker sheet implants	1236:1261	the thicker sheet implants	1236:1261	At week 16 postimplantation, airway stenosis was noticed under the thicker sheet implants, but not the thinner implants, suggesting that the thinner (1 mm thick) scaffolded cartilage sheet was an optimal candidate for tracheal reconstruction in this study.					
35137630	15	99	theme	personalized	2228:2239	arg1	medicine					2254:2261	personalized regenerative medicine	2228:2261	personalized regenerative medicine	2228:2261	The cartilage sheets were thought of as biomaterials for personalized regenerative medicine since the dimensions, thickness, and pore sizes of cartilage sheets were tunable to fit the lesions that need to be reconstructed.					
35137630	8	100	theme	collagen	1041:1048	arg1	fibers					1050:1055	profibrotic collagen fibers	1029:1055	profibrotic collagen fibers	1029:1055	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
35137630	8	101	theme	profibrotic	1029:1039	arg1	fibers					1050:1055	profibrotic collagen fibers	1029:1055	profibrotic collagen fibers	1029:1055	However, the invasive migration of fibrous tissue and profibrotic collagen fibers into cartilage implants and the peripheral space surrounding the implants were elevated in a time-dependent manner.					
37245751	2	0	used	used	417:420	arg2	acid					408:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	3	1	theme	coaxial	520:526	arg1	spinning					541:548	the coaxial microfluidic spinning	516:548	the coaxial microfluidic spinning	516:548	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	0	2	theme	antibacterial	83:95	arg1	activity					97:104	antibacterial activity	83:104	antibacterial activity	83:104	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	6	3	theme	high	1108:1111	arg1	strength					1113:1120	high strength	1108:1120	high strength	1108:1120	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	3	4	theme	microfluidic	528:539	arg1	spinning					541:548	the coaxial microfluidic spinning	516:548	the coaxial microfluidic spinning	516:548	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	5	5	theme	experimental	999:1010	arg1	R2 = 0.99					1018:1026	R2 = 0.99	1018:1026	R2 = 0.99	1018:1026	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	5	5	theme	experimental	999:1010	arg1	data					1012:1015	the experimental data	995:1015	the experimental data (R2 = 0.99)	995:1027	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	0	6	theme	drug	110:113	arg1	release					115:121	drug release	110:121	drug release	110:121	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	3	7	theme	spinning	541:548	arg1	parameters					502:511	the process parameters	490:511	the process parameters of the coaxial microfluidic spinning	490:548	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	6	8	theme	spin	1228:1231	arg1	technology					1233:1242	coaxial microfluidic spin technology	1207:1242	coaxial microfluidic spin technology	1207:1242	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	3	9	theme	alginate	586:593	arg1	membrane					595:602	the alginate membrane	582:602	the alginate membrane	582:602	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	4	10	theme	oxygen	776:781	arg1	species					783:789	reactive oxygen species	767:789	reactive oxygen species (ROS)	767:795	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	10	theme	oxygen	776:781	arg1	ROS					792:794	ROS	792:794	ROS	792:794	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	6	11	theme	drug	1283:1286	arg1	release					1288:1294	drug release	1283:1294	drug release	1283:1294	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	4	12	theme	disruptive	746:755	arg1	effect					757:762	the disruptive effect	742:762	the disruptive effect of reactive oxygen species (ROS) on bacteria	742:807	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	2	13	theme	alginate	268:275	arg1	membrane					277:284	an oriented fibrous alginate membrane	248:284	an oriented fibrous alginate membrane with sufficient strength	248:309	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	6	14	theme	dressing	1084:1091	arg1	materials					1093:1101	dressing materials	1084:1101	dressing materials with high strength and directional drug delivery	1084:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	5	15	theme	mathematical	912:923	arg1	model					940:944	a mathematical drug diffusion model	910:944	a mathematical drug diffusion model	910:944	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	6	16	theme	directional	1126:1136	arg1	delivery					1143:1150	directional drug delivery	1126:1150	directional drug delivery	1126:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	2	17	theme	fibrous	260:266	arg1	membrane					277:284	an oriented fibrous alginate membrane	248:284	an oriented fibrous alginate membrane with sufficient strength	248:309	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	6	18	theme	materials	1093:1101	arg1	preparation					1069:1079	the preparation	1065:1079	the preparation of dressing materials with high strength and directional drug delivery	1065:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	0	19	theme	microfluidic	8:19	arg1	design					30:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	6	20	theme	functional	1258:1267	arg1	materials					1269:1277	functional materials	1258:1277	functional materials for drug release	1258:1294	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	3	21	theme	membrane	595:602	arg1	properties					568:577	the mechanical properties	553:577	the mechanical properties of the alginate membrane	553:602	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	6	22	with	materials	1093:1101	arg1	strength					1113:1120	high strength	1108:1120	high strength	1108:1120	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	6	22	with	materials	1093:1101	arg1	delivery					1143:1150	directional drug delivery	1126:1150	directional drug delivery	1126:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	4	23	theme	imidazolate	700:710	arg1	framework-8					712:722	zeolitic imidazolate framework-8	691:722	zeolitic imidazolate framework-8	691:722	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	0	24	theme	Coaxial	0:6	arg1	design					30:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	4	25	theme	reactive	767:774	arg1	species					783:789	reactive oxygen species	767:789	reactive oxygen species (ROS)	767:795	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	25	theme	reactive	767:774	arg1	ROS					792:794	ROS	792:794	ROS	792:794	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	2	26	theme	framework-8/ascorbic	387:406	arg1	acid					408:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	2	27	theme	antibacterial	451:463	arg1	activity					465:472	antibacterial activity	451:472	antibacterial activity	451:472	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	6	28	theme	coaxial	1207:1213	arg1	technology					1233:1242	coaxial microfluidic spin technology	1207:1242	coaxial microfluidic spin technology	1207:1242	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	4	29	theme	generated	841:849	arg1	ROS					851:853	generated ROS	841:853	generated ROS	841:853	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	6	30	theme	new	1052:1054	arg1	idea					1056:1059	a new idea	1050:1059	a new idea for the preparation of dressing materials with high strength and directional drug delivery	1050:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	5	31	theme	high	973:976	arg1	consistency					978:988	high consistency	973:988	high consistency with the experimental data (R2 = 0.99)	973:1027	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	0	32	theme	spinning	21:28	arg1	design					30:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design	0:35	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	2	33	theme	sufficient	291:300	arg1	strength					302:309	sufficient strength	291:309	sufficient strength	291:309	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	2	34	theme	drug	433:436	arg1	delivery					438:445	drug delivery	433:445	drug delivery	433:445	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	0	35	theme	high	46:49	arg1	membranes					69:77	high strength alginate membranes	46:77	high strength alginate membranes for antibacterial activity and drug release	46:121	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	2	36	theme	microfluidic	339:350	arg1	spinning					352:359	coaxial microfluidic spinning	331:359	coaxial microfluidic spinning	331:359	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	6	37	theme	drug	1138:1141	arg1	delivery					1143:1150	directional drug delivery	1126:1150	directional drug delivery	1126:1150	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	4	38	theme	zeolitic	691:698	arg1	framework-8					712:722	zeolitic imidazolate framework-8	691:722	zeolitic imidazolate framework-8	691:722	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	39	theme	activity	669:676	arg1	mechanism					678:686	the antimicrobial activity mechanism	651:686	the antimicrobial activity mechanism of zeolitic imidazolate framework-8	651:722	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	5	40	theme	diffusion	930:938	arg1	model					940:944	a mathematical drug diffusion model	910:944	a mathematical drug diffusion model	910:944	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	1	41	theme	wound	217:221	arg1	dressing					223:230	wound dressing	217:230	wound dressing	217:230	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	0	42	theme	alginate	60:67	arg1	membranes					69:77	high strength alginate membranes	46:77	high strength alginate membranes for antibacterial activity and drug release	46:121	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	4	43	theme	ROS	851:853	arg1	amount					831:836	the quantitative amount	814:836	the quantitative amount of generated ROS	814:853	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	43	theme	ROS	851:853	arg1	ROS					851:853	generated ROS	841:853	generated ROS	841:853	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	3	44	from	effects	479:485	arg1	properties					568:577	the mechanical properties	553:577	the mechanical properties of the alginate membrane	553:602	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	1	45	theme	Directional	124:134	arg1	delivery					141:148	Directional drug delivery	124:148	Directional drug delivery	124:148	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	45	theme	Directional	124:134	arg1	strength					165:172	sufficient strength	154:172	sufficient strength	154:172	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	45	theme	Directional	124:134	arg1	conditions					182:191	two conditions	178:191	two conditions that need to be met for wound dressing	178:230	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	0	46	theme	strength	51:58	arg1	membranes					69:77	high strength alginate membranes	46:77	high strength alginate membranes for antibacterial activity and drug release	46:121	Coaxial microfluidic spinning design produced high strength alginate membranes for antibacterial activity and drug release.					
37245751	4	47	located	found	640:644	arg2	it					633:634	it	633:634	it	633:634	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	47	located	found	640:644	arg1	addition					623:630	addition	623:630	addition	623:630	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	1	48	theme	drug	136:139	arg1	delivery					141:148	Directional drug delivery	124:148	Directional drug delivery	124:148	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	48	theme	drug	136:139	arg1	strength					165:172	sufficient strength	154:172	sufficient strength	154:172	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	48	theme	drug	136:139	arg1	conditions					182:191	two conditions	178:191	two conditions that need to be met for wound dressing	178:230	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	6	49	theme	technology	1233:1242	arg1	development					1192:1202	the development	1188:1202	the development of coaxial microfluidic spin technology	1188:1242	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	1	50	theme	sufficient	154:163	arg1	delivery					141:148	Directional drug delivery	124:148	Directional drug delivery	124:148	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	50	theme	sufficient	154:163	arg1	strength					165:172	sufficient strength	154:172	sufficient strength	154:172	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	1	50	theme	sufficient	154:163	arg1	conditions					182:191	two conditions	178:191	two conditions that need to be met for wound dressing	178:230	Directional drug delivery and sufficient strength are two conditions that need to be met for wound dressing.					
37245751	2	51	theme	oriented	251:258	arg1	membrane					277:284	an oriented fibrous alginate membrane	248:284	an oriented fibrous alginate membrane with sufficient strength	248:309	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	4	52	theme	framework-8	712:722	arg1	mechanism					678:686	the antimicrobial activity mechanism	651:686	the antimicrobial activity mechanism of zeolitic imidazolate framework-8	651:722	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	2	53	theme	coaxial	331:337	arg1	spinning					352:359	coaxial microfluidic spinning	331:359	coaxial microfluidic spinning	331:359	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	4	54	from	effect	757:762	arg1	bacteria					800:807	bacteria	800:807	bacteria	800:807	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	3	55	theme	mechanical	557:566	arg1	properties					568:577	the mechanical properties	553:577	the mechanical properties of the alginate membrane	553:602	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	5	56	theme	drug	925:928	arg1	model					940:944	a mathematical drug diffusion model	910:944	a mathematical drug diffusion model	910:944	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	6	57	theme	microfluidic	1215:1226	arg1	technology					1233:1242	coaxial microfluidic spin technology	1207:1242	coaxial microfluidic spin technology	1207:1242	This study provides a new idea for the preparation of dressing materials with high strength and directional drug delivery and also provides some guidance for the development of coaxial microfluidic spin technology to be used in functional materials for drug release.					
37245751	4	58	theme	species	783:789	arg1	effect					757:762	the disruptive effect	742:762	the disruptive effect of reactive oxygen species (ROS) on bacteria	742:807	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	3	59	theme	parameters	502:511	arg1	effects					479:485	The effects	475:485	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane	475:602	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	3	60	theme	process	494:500	arg1	parameters					502:511	the process parameters	490:511	the process parameters of the coaxial microfluidic spinning	490:548	The effects of the process parameters of the coaxial microfluidic spinning on the mechanical properties of the alginate membrane were discussed.					
37245751	4	61	theme	antimicrobial	655:667	arg1	mechanism					678:686	the antimicrobial activity mechanism	651:686	the antimicrobial activity mechanism of zeolitic imidazolate framework-8	651:722	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	62	theme	quantitative	818:829	arg1	amount					831:836	the quantitative amount	814:836	the quantitative amount of generated ROS	814:853	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	4	62	theme	quantitative	818:829	arg1	ROS					851:853	generated ROS	841:853	generated ROS	841:853	In addition, it was found that the antimicrobial activity mechanism of zeolitic imidazolate framework-8 was attributed to the disruptive effect of reactive oxygen species (ROS) on bacteria, and the quantitative amount of generated ROS were evaluated by detecting •OH and H2O2.					
37245751	2	63	theme	imidazolate	375:385	arg1	acid					408:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	5	64	with	consistency	978:988	arg1	R2 = 0.99					1018:1026	R2 = 0.99	1018:1026	R2 = 0.99	1018:1026	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	5	64	with	consistency	978:988	arg1	data					1012:1015	the experimental data	995:1015	the experimental data (R2 = 0.99)	995:1027	Furthermore, a mathematical drug diffusion model was established and showed high consistency with the experimental data (R2 = 0.99).					
37245751	2	65	theme	zeolitic	366:373	arg1	acid					408:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	zeolitic imidazolate framework-8/ascorbic acid	366:411	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37245751	2	66	with	membrane	277:284	arg1	strength					302:309	sufficient strength	291:309	sufficient strength	291:309	In this paper, an oriented fibrous alginate membrane with sufficient strength was constructed via coaxial microfluidic spinning, and zeolitic imidazolate framework-8/ascorbic acid was used to realize drug delivery and antibacterial activity.					
37162583	6	0	theme	soil	809:812	arg1	capacity					793:800	the water holding capacity	775:800	the water holding capacity of the soil	775:812	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	10	1	theme	lowered	1636:1642	arg1	contents					1622:1629	the malondialdehyde contents	1602:1629	the malondialdehyde contents	1602:1629	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	10	1	theme	lowered	1636:1642	arg1	%					1651:1651	lowered by > 15%	1636:1651	lowered by > 15%	1636:1651	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	12	2	theme	phosphate	1904:1912	arg1	uptake					1894:1899	the uptake	1890:1899	the uptake of phosphate by sunflower roots	1890:1931	Additionally, the hydrogel promoted the uptake of phosphate by sunflower roots.					
37162583	9	3	theme	%	1493:1493	arg1	FC					1495:1496	100% FC	1490:1496	100% FC	1490:1496	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	9	3	theme	%	1493:1493	arg1	control					1481:1487	the well-watered control	1464:1487	the well-watered control (100% FC)	1464:1497	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	12	4	theme	sunflower	1917:1925	arg1	roots					1927:1931	sunflower roots	1917:1931	sunflower roots	1917:1931	Additionally, the hydrogel promoted the uptake of phosphate by sunflower roots.					
37162583	0	5	link	Macroalgal-derived	0:17	arg1	hydrogel					39:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel to alleviate sunflower drought stress.					
37162583	8	6	theme	various	1191:1197	arg1	by > 2-					1259:1265	length by > 2-	1252:1265	length by > 2-	1252:1265	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	and > 1.3-folds					1285:1299	and > 1.3-folds	1285:1299	and > 1.3-folds	1285:1299	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	traits					1204:1209	various root traits	1191:1209	various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds	1191:1299	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	biomass					1233:1239	fresh and dry biomass	1219:1239	fresh and dry biomass	1219:1239	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	area					1242:1245	area	1242:1245	area	1242:1245	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	 > 1.6-					1267:1273	 > 1.6-	1267:1273	 > 1.6-	1267:1273	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	6	theme	various	1191:1197	arg1	 > 1.35-					1275:1282	 > 1.35-	1275:1282	 > 1.35-	1275:1282	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	7	7	theme	column	1045:1050	arg1	experiment					1052:1061	a column experiment	1043:1061	a column experiment	1043:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	6	8	theme	holding	785:791	arg1	capacity					793:800	the water holding capacity	775:800	the water holding capacity of the soil	775:812	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	8	9	from	regimes	1318:1324	arg1	relation					1329:1336	relation	1329:1336	relation to the no-hydrogel treatments at the same conditions	1329:1389	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	6	10	theme	PO4-	863:866	arg1	hydrogel					872:879	37 mg PO4- g-1 hydrogel	857:879	37 mg PO4- g-1 hydrogel after 6 days	857:892	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	10	theme	PO4-	863:866	arg1	adsorption					845:854	a good phosphate adsorption	828:854	a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days)	828:893	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	11	11	from	reduction	1718:1726	arg1	activities					1744:1753	the specific activities	1731:1753	the specific activities of catalase and ascorbate peroxidase	1731:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	4	12	theme	%	597:597	arg1	FC					615:616	FC	615:616	FC	615:616	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	12	theme	%	597:597	arg1	capacity					605:612	75% field capacity	595:612	75% field capacity (FC)	595:617	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	5	13	theme	fast	683:686	arg1	swelling					688:695	fast swelling	683:695	fast swelling	683:695	The hydrogel showed fast swelling in water, which obeyed the pseudo-first order kinetics.					
37162583	7	14	dep	2.77 mg	1072:1078	arg1	compared					1114:1121	compared	1114:1121	compared to 11.91 mg without the hydrogel	1114:1154	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	14	dep	2.77 mg	1072:1078	arg1	leaching					1000:1007	the phosphate leaching	986:1007	the phosphate leaching from the hydrogel-amended soil in a column experiment	986:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	14	dep	2.77 mg	1072:1078	arg1	2.77 mg					1072:1078	2.77 mg	1072:1078	2.77 mg	1072:1078	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	15	theme	hydrogel-amended	1018:1033	arg1	soil					1035:1038	the hydrogel-amended soil	1014:1038	the hydrogel-amended soil in a column experiment	1014:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	4	16	theme	water-deficit	641:653	arg1	stress					655:660	water-deficit stress	641:660	water-deficit stress	641:660	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	8	17	theme	same	1375:1378	arg1	conditions					1380:1389	the same conditions	1371:1389	the same conditions	1371:1389	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	7	18	theme	phosphate	990:998	arg1	compared					1114:1121	compared	1114:1121	compared to 11.91 mg without the hydrogel	1114:1154	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	18	theme	phosphate	990:998	arg1	leaching					1000:1007	the phosphate leaching	986:1007	the phosphate leaching from the hydrogel-amended soil in a column experiment	986:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	18	theme	phosphate	990:998	arg1	2.77 mg					1072:1078	2.77 mg	1072:1078	2.77 mg	1072:1078	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	2	19	theme	sunflower	261:269	arg1	growth					271:276	sunflower growth	261:276	sunflower growth	261:276	The hydrogel promoted sunflower growth and decreased stress related biomarkers.					
37162583	9	20	theme	similar	1436:1442	arg1	contents					1452:1459	similar proline contents	1436:1459	similar proline contents	1436:1459	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	3	21	theme	hydrogels	383:391	arg1	development					354:364	the development	350:364	the development of biodegradable hydrogels	350:391	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	4	22	theme	algal-derived	474:486	arg1	alginate					488:495	brown algal-derived alginate	468:495	brown algal-derived alginate	468:495	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	13	23	theme	biodegradable	1975:1987	arg1	hydrogel					1989:1996	the developed biodegradable hydrogel	1961:1996	the developed biodegradable hydrogel	1961:1996	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	13	23	theme	biodegradable	1975:1987	arg1	soil					2032:2035	a soil	2030:2035	a soil additive to alleviate drought stress on crops	2030:2081	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	2	24	theme	stress	292:297	arg1	biomarkers					307:316	stress related biomarkers	292:316	stress related biomarkers	292:316	The hydrogel promoted sunflower growth and decreased stress related biomarkers.					
37162583	4	25	theme	soil	542:545	arg1	supplement					547:556	a soil supplement	540:556	a soil supplement for sunflower growth	540:577	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	25	theme	soil	542:545	arg1	hydrogel					450:457	A novel hydrogel	442:457	A novel hydrogel based on brown algal-derived alginate and wastepaper	442:510	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	1	26	theme	soil	199:202	arg1	capacity					183:190	the water holding capacity	165:190	the water holding capacity of the soil	165:202	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	4	27	link	algal-derived	474:486	arg1	alginate					488:495	brown algal-derived alginate	468:495	brown algal-derived alginate	468:495	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	11	28	theme	antioxidant	1674:1684	arg1	enzymes					1686:1692	the antioxidant enzymes	1670:1692	the antioxidant enzymes	1670:1692	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	5	29	theme	pseudo-first	724:735	arg1	kinetics					743:750	the pseudo-first order kinetics	720:750	the pseudo-first order kinetics	720:750	The hydrogel showed fast swelling in water, which obeyed the pseudo-first order kinetics.					
37162583	1	30	theme	Alginate/wastepaper	87:105	arg1	hydrogel					107:114	Alginate/wastepaper hydrogel	87:114	Alginate/wastepaper hydrogel	87:114	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	1	31	theme	holding	175:181	arg1	capacity					183:190	the water holding capacity	165:190	the water holding capacity of the soil	165:202	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	9	32	theme	100	1490:1492	arg1	%					1493:1493	%	1493:1493	%	1493:1493	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	0	33	theme	Macroalgal-derived	0:17	arg1	hydrogel					39:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel to alleviate sunflower drought stress.					
37162583	1	34	theme	drought	136:142	arg1	stress					144:149	sunflower drought stress	126:149	sunflower drought stress	126:149	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	9	35	from	reduction	1511:1519	arg1	relation					1524:1531	relation	1524:1531	relation to the drought-stressed plants	1524:1562	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	3	36	theme	stress	424:429	arg1	alleviation					401:411	the alleviation	397:411	the alleviation of drought stress on plants	397:439	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	4	37	theme	75	595:596	arg1	%					597:597	%	597:597	%	597:597	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	11	38	theme	respective	1833:1842	arg1	controls					1844:1851	the respective controls	1829:1851	the respective controls	1829:1851	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	6	39	theme	37 mg	857:861	arg1	hydrogel					872:879	37 mg PO4- g-1 hydrogel	857:879	37 mg PO4- g-1 hydrogel after 6 days	857:892	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	39	theme	37 mg	857:861	arg1	adsorption					845:854	a good phosphate adsorption	828:854	a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days)	828:893	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	4	40	theme	field	599:603	arg1	FC					615:616	FC	615:616	FC	615:616	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	40	theme	field	599:603	arg1	capacity					605:612	75% field capacity	595:612	75% field capacity (FC)	595:617	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	9	41	theme	%	1509:1509	arg1	reduction					1511:1519	with > 50% reduction	1500:1519	with > 50% reduction in relation to the drought-stressed plants	1500:1562	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	11	42	theme	ascorbate	1771:1779	arg1	peroxidase					1781:1790	ascorbate peroxidase	1771:1790	ascorbate peroxidase	1771:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	0	43	theme	drought	71:77	arg1	stress					79:84	sunflower drought stress	61:84	sunflower drought stress	61:84	Macroalgal-derived alginate/wastepaper hydrogel to alleviate sunflower drought stress.					
37162583	6	44	theme	good	830:833	arg1	hydrogel					872:879	37 mg PO4- g-1 hydrogel	857:879	37 mg PO4- g-1 hydrogel after 6 days	857:892	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	44	theme	good	830:833	arg1	adsorption					845:854	a good phosphate adsorption	828:854	a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days)	828:893	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	11	45	dep	%	1812:1812	arg1	50					1810:1811	50	1810:1811	50	1810:1811	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	11	45	dep	%	1812:1812	arg1	75					1803:1804	75	1803:1804	75	1803:1804	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	11	46	theme	catalase	1758:1765	arg1	activities					1744:1753	the specific activities	1731:1753	the specific activities of catalase and ascorbate peroxidase	1731:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	3	47	from	interest	338:345	arg1	development					354:364	the development	350:364	the development of biodegradable hydrogels	350:391	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	9	48	theme	drought-stressed	1540:1555	arg1	plants					1557:1562	the drought-stressed plants	1536:1562	the drought-stressed plants	1536:1562	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	10	49	theme	by > 15	1644:1650	arg1	contents					1622:1629	the malondialdehyde contents	1602:1629	the malondialdehyde contents	1602:1629	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	10	49	theme	by > 15	1644:1650	arg1	%					1651:1651	lowered by > 15%	1636:1651	lowered by > 15%	1636:1651	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	13	50	theme	drought	2059:2065	arg1	stress					2067:2072	drought stress	2059:2072	drought stress on crops	2059:2081	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	4	51	theme	novel	444:448	arg1	supplement					547:556	a soil supplement	540:556	a soil supplement for sunflower growth	540:577	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	51	theme	novel	444:448	arg1	hydrogel					450:457	A novel hydrogel	442:457	A novel hydrogel based on brown algal-derived alginate and wastepaper	442:510	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	9	52	theme	same	1574:1577	arg1	conditions					1579:1588	the same conditions	1570:1588	the same conditions	1570:1588	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	6	53	theme	g-1	868:870	arg1	hydrogel					872:879	37 mg PO4- g-1 hydrogel	857:879	37 mg PO4- g-1 hydrogel after 6 days	857:892	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	53	theme	g-1	868:870	arg1	adsorption					845:854	a good phosphate adsorption	828:854	a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days)	828:893	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	54	theme	water	779:783	arg1	capacity					793:800	the water holding capacity	775:800	the water holding capacity of the soil	775:812	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	1	55	theme	phosphate	219:227	arg1	leaching					229:236	phosphate leaching	219:236	phosphate leaching	219:236	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	8	56	theme	root	1199:1202	arg1	by > 2-					1259:1265	length by > 2-	1252:1265	length by > 2-	1252:1265	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	and > 1.3-folds					1285:1299	and > 1.3-folds	1285:1299	and > 1.3-folds	1285:1299	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	traits					1204:1209	various root traits	1191:1209	various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds	1191:1299	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	biomass					1233:1239	fresh and dry biomass	1219:1239	fresh and dry biomass	1219:1239	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	area					1242:1245	area	1242:1245	area	1242:1245	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	 > 1.6-					1267:1273	 > 1.6-	1267:1273	 > 1.6-	1267:1273	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	8	56	theme	root	1199:1202	arg1	 > 1.35-					1275:1282	 > 1.35-	1275:1282	 > 1.35-	1275:1282	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	3	57	theme	growing	330:336	arg1	interest					338:345	a growing interest	328:345	a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants	328:439	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	4	58	theme	%	635:635	arg1	extreme					624:630	extreme	624:630	extreme	624:630	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	58	theme	%	635:635	arg1	FC					637:638	50% FC	633:638	50% FC	633:638	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	11	59	theme	marked	1711:1716	arg1	reduction					1718:1726	a marked reduction	1709:1726	a marked reduction in the specific activities of catalase and ascorbate peroxidase	1709:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	3	60	from	alleviation	401:411	arg1	plants					434:439	plants	434:439	plants	434:439	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	6	61	theme	phosphate	942:950	arg1	phosphate					942:950	the adsorbed phosphate	929:950	the adsorbed phosphate	929:950	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	61	theme	phosphate	942:950	arg1	%					924:924	more than 67%	912:924	more than 67% of the adsorbed phosphate	912:950	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	8	62	theme	fresh	1219:1223	arg1	biomass					1233:1239	fresh and dry biomass	1219:1239	fresh and dry biomass	1219:1239	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	9	63	theme	sunflower	1409:1417	arg1	shoots					1419:1424	the sunflower shoots	1405:1424	the sunflower shoots	1405:1424	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	8	64	theme	hydrogel	1161:1168	arg1	application					1170:1180	The hydrogel application	1157:1180	The hydrogel application	1157:1180	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	4	65	theme	brown	468:472	arg1	alginate					488:495	brown algal-derived alginate	468:495	brown algal-derived alginate	468:495	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	8	66	theme	dry	1229:1231	arg1	biomass					1233:1239	fresh and dry biomass	1219:1239	fresh and dry biomass	1219:1239	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	11	67	theme	specific	1735:1742	arg1	activities					1744:1753	the specific activities	1731:1753	the specific activities of catalase and ascorbate peroxidase	1731:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	1	68	theme	water	169:173	arg1	capacity					183:190	the water holding capacity	165:190	the water holding capacity of the soil	165:202	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	10	69	theme	malondialdehyde	1606:1620	arg1	contents					1622:1629	the malondialdehyde contents	1602:1629	the malondialdehyde contents	1602:1629	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	10	69	theme	malondialdehyde	1606:1620	arg1	%					1651:1651	lowered by > 15%	1636:1651	lowered by > 15%	1636:1651	Similarly, the malondialdehyde contents were lowered by > 15%.					
37162583	8	70	from	conditions	1380:1389	arg1	treatments					1357:1366	the no-hydrogel treatments	1341:1366	the no-hydrogel treatments at the same conditions	1341:1389	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	2	71	theme	related	299:305	arg1	biomarkers					307:316	stress related biomarkers	292:316	stress related biomarkers	292:316	The hydrogel promoted sunflower growth and decreased stress related biomarkers.					
37162583	9	72	theme	proline	1444:1450	arg1	contents					1452:1459	similar proline contents	1436:1459	similar proline contents	1436:1459	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	5	73	from	swelling	688:695	arg1	water					700:704	water	700:704	water	700:704	The hydrogel showed fast swelling in water, which obeyed the pseudo-first order kinetics.					
37162583	4	74	dep	moderate	585:592	arg1	FC					615:616	FC	615:616	FC	615:616	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	74	dep	moderate	585:592	arg1	stress					655:660	water-deficit stress	641:660	water-deficit stress	641:660	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	4	74	dep	moderate	585:592	arg1	capacity					605:612	75% field capacity	595:612	75% field capacity (FC)	595:617	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	3	75	theme	biodegradable	369:381	arg1	hydrogels					383:391	biodegradable hydrogels	369:391	biodegradable hydrogels	369:391	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	4	76	theme	sunflower	562:570	arg1	growth					572:577	sunflower growth	562:577	sunflower growth	562:577	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	8	77	theme	length	1252:1257	arg1	by > 2-					1259:1265	length by > 2-	1252:1265	length by > 2-	1252:1265	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	9	78	theme	well-watered	1468:1479	arg1	FC					1495:1496	100% FC	1490:1496	100% FC	1490:1496	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	9	78	theme	well-watered	1468:1479	arg1	control					1481:1487	the well-watered control	1464:1487	the well-watered control (100% FC)	1464:1497	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	6	79	theme	adsorbed	933:940	arg1	phosphate					942:950	the adsorbed phosphate	929:950	the adsorbed phosphate	929:950	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	3	80	theme	drought	416:422	arg1	stress					424:429	drought stress	416:429	drought stress	416:429	There is a growing interest in the development of biodegradable hydrogels for the alleviation of drought stress on plants.					
37162583	11	81	theme	enzymes	1686:1692	arg1	analysis					1658:1665	The analysis	1654:1665	The analysis of the antioxidant enzymes	1654:1692	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	5	82	theme	order	737:741	arg1	kinetics					743:750	the pseudo-first order kinetics	720:750	the pseudo-first order kinetics	720:750	The hydrogel showed fast swelling in water, which obeyed the pseudo-first order kinetics.					
37162583	0	83	theme	alginate/wastepaper	19:37	arg1	hydrogel					39:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel	0:46	Macroalgal-derived alginate/wastepaper hydrogel to alleviate sunflower drought stress.					
37162583	13	84	theme	developed	1965:1973	arg1	hydrogel					1989:1996	the developed biodegradable hydrogel	1961:1996	the developed biodegradable hydrogel	1961:1996	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	13	84	theme	developed	1965:1973	arg1	soil					2032:2035	a soil	2030:2035	a soil additive to alleviate drought stress on crops	2030:2081	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	1	85	theme	sunflower	126:134	arg1	stress					144:149	sunflower drought stress	126:149	sunflower drought stress	126:149	Alginate/wastepaper hydrogel mitigated sunflower drought stress by increasing the water holding capacity of the soil and decreasing phosphate leaching.					
37162583	7	86	from	soil	1035:1038	arg1	compared					1114:1121	compared	1114:1121	compared to 11.91 mg without the hydrogel	1114:1154	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	86	from	soil	1035:1038	arg1	experiment					1052:1061	a column experiment	1043:1061	a column experiment	1043:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	86	from	soil	1035:1038	arg1	leaching					1000:1007	the phosphate leaching	986:1007	the phosphate leaching from the hydrogel-amended soil in a column experiment	986:1061	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	7	86	from	soil	1035:1038	arg1	2.77 mg					1072:1078	2.77 mg	1072:1078	2.77 mg	1072:1078	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	13	87	theme	additive	2037:2044	arg1	hydrogel					1989:1996	the developed biodegradable hydrogel	1961:1996	the developed biodegradable hydrogel	1961:1996	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	13	87	theme	additive	2037:2044	arg1	soil					2032:2035	a soil	2030:2035	a soil additive to alleviate drought stress on crops	2030:2081	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	7	88	theme	over-irrigation	1097:1111	arg1	times					1088:1092	4 times	1086:1092	4 times of over-irrigation	1086:1111	Thus, the phosphate leaching from the hydrogel-amended soil in a column experiment was only 2.77 mg after 4 times of over-irrigation, compared to 11.91 mg without the hydrogel.					
37162583	0	89	theme	sunflower	61:69	arg1	stress					79:84	sunflower drought stress	61:84	sunflower drought stress	61:84	Macroalgal-derived alginate/wastepaper hydrogel to alleviate sunflower drought stress.					
37162583	9	90	theme	with > 50	1500:1508	arg1	%					1509:1509	%	1509:1509	%	1509:1509	Furthermore, the sunflower shoots exhibited similar proline contents to the well-watered control (100% FC), with > 50% reduction in relation to the drought-stressed plants under the same conditions.					
37162583	13	91	from	stress	2067:2072	arg1	crops					2077:2081	crops	2077:2081	crops	2077:2081	These results implied that the developed biodegradable hydrogel could be effectively applied as a soil additive to alleviate drought stress on crops.					
37162583	8	92	theme	water	1312:1316	arg1	regimes					1318:1324	both water regimes	1307:1324	both water regimes in relation to the no-hydrogel treatments at the same conditions	1307:1389	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
37162583	6	93	theme	phosphate	835:843	arg1	hydrogel					872:879	37 mg PO4- g-1 hydrogel	857:879	37 mg PO4- g-1 hydrogel after 6 days	857:892	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	6	93	theme	phosphate	835:843	arg1	adsorption					845:854	a good phosphate adsorption	828:854	a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days)	828:893	Besides, it increased the water holding capacity of the soil and exhibited a good phosphate adsorption (37 mg PO4- g-1 hydrogel after 6 days) in the soil, and more than 67% of the adsorbed phosphate was desorbed after 20 days.					
37162583	11	94	dep	FC	1814:1815	arg1	%					1812:1812	%	1812:1812	%	1812:1812	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	11	95	theme	peroxidase	1781:1790	arg1	activities					1744:1753	the specific activities	1731:1753	the specific activities of catalase and ascorbate peroxidase	1731:1790	The analysis of the antioxidant enzymes also indicated a marked reduction in the specific activities of catalase and ascorbate peroxidase under both 75 and 50% FC compared to the respective controls.					
37162583	4	96	theme	50	633:634	arg1	%					635:635	%	635:635	%	635:635	A novel hydrogel based on brown algal-derived alginate and wastepaper was developed and tested as a soil supplement for sunflower growth under moderate (75% field capacity (FC)) and extreme (50% FC) water-deficit stress.					
37162583	8	97	theme	no-hydrogel	1345:1355	arg1	treatments					1357:1366	the no-hydrogel treatments	1341:1366	the no-hydrogel treatments at the same conditions	1341:1389	The hydrogel application promoted various root traits such as fresh and dry biomass, area, and length by > 2-, > 1.6-, > 1.35-, and > 1.3-folds under both water regimes in relation to the no-hydrogel treatments at the same conditions.					
35661672	2	0	theme	reinforcement	302:314	arg1	mechanisms					316:325	The reinforcement mechanisms	298:325	The reinforcement mechanisms	298:325	The reinforcement mechanisms were investigated by the elastoplasticity and fracture appearance.					
35661672	0	1	theme	celluloses	69:78	arg1	comparison					55:64	A comparison	53:64	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.	0:103	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	3	2	theme	Col-CNF	461:467	arg1	films					469:473	the Col-CNF films	457:473	the Col-CNF films	457:473	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	4	3	from	%	808:808	arg1	strain-to-break					773:787	the strain-to-break	769:787	the strain-to-break from 8.37% to 12.13%	769:808	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	6	4	from	effects	940:946	arg1	stability					1026:1034	thermal stability	1018:1034	thermal stability	1018:1034	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	4	from	effects	940:946	arg1	crystallinity					1037:1049	crystallinity	1037:1049	crystallinity	1037:1049	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	4	from	effects	940:946	arg1	density					992:998	density	992:998	density	992:998	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	4	from	effects	940:946	arg1	water-tightness					1001:1015	water-tightness	1001:1015	water-tightness	1001:1015	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	4	from	effects	940:946	arg1	FTIR					1055:1058	FTIR	1055:1058	FTIR	1055:1058	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	4	from	effects	940:946	arg1	thickness					981:989	thickness	981:989	thickness	981:989	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	1	5	from	celluloses	145:154	arg1	geometries					169:178	different geometries	159:178	different geometries	159:178	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	nanocrystals					278:289	cellulose nanocrystals	268:289	cellulose nanocrystals (CNC)	268:295	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	fines					226:230	cellulosic fines	215:230	cellulosic fines (CF)	215:235	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	nanofiber					248:256	cellulose nanofiber	238:256	cellulose nanofiber (CNF)	238:262	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	cellulose					198:206	microcrystalline cellulose	181:206	microcrystalline cellulose (MCC)	181:212	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	CNF					259:261	CNF	259:261	CNF	259:261	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	CNC					292:294	CNC	292:294	CNC	292:294	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	MCC					209:211	MCC	209:211	MCC	209:211	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	5	from	celluloses	145:154	arg1	CF					233:234	CF	233:234	CF	233:234	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	5	6	theme	mechanical	907:916	arg1	locking					918:924	mechanical locking	907:924	mechanical locking	907:924	The films added with MCC and CNC weaken the mechanical behavior, due to the defects and lack of mechanical locking.					
35661672	0	7	theme	different	83:91	arg1	geometries					93:102	different geometries	83:102	different geometries	83:102	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	4	8	theme	films	664:668	arg1	toughness					644:652	The toughness	640:652	The toughness of Col-CF films	640:668	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	6	9	theme	thermal	1018:1024	arg1	stability					1026:1034	thermal stability	1018:1034	thermal stability	1018:1034	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	4	10	theme	Col-CF	657:662	arg1	films					664:668	Col-CF films	657:668	Col-CF films	657:668	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	4	11	theme	CF	737:738	arg1	pull-off					725:732	pull-off	725:732	pull-off	725:732	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	7	12	theme	adjustable	1238:1247	arg1	properties					1260:1269	adjustable mechanical properties	1238:1269	adjustable mechanical properties	1238:1269	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35661672	4	13	theme	8.37	794:797	arg1	%					798:798	%	798:798	%	798:798	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	1	14	theme	different	159:167	arg1	geometries					169:178	different geometries	159:178	different geometries	159:178	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	0	15	theme	mechanical	8:17	arg1	behavior					19:26	Tunable mechanical behavior	0:26	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.	0:103	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	4	16	theme	12.13	803:807	arg1	%					798:798	%	798:798	%	798:798	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	5	17	theme	locking	918:924	arg1	defects					887:893	the defects	883:893	the defects	883:893	The films added with MCC and CNC weaken the mechanical behavior, due to the defects and lack of mechanical locking.					
35661672	5	17	theme	locking	918:924	arg1	lack					899:902	lack	899:902	lack of mechanical locking	899:924	The films added with MCC and CNC weaken the mechanical behavior, due to the defects and lack of mechanical locking.					
35661672	6	18	theme	films	1063:1067	arg1	stability					1026:1034	thermal stability	1018:1034	thermal stability	1018:1034	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	18	theme	films	1063:1067	arg1	crystallinity					1037:1049	crystallinity	1037:1049	crystallinity	1037:1049	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	18	theme	films	1063:1067	arg1	density					992:998	density	992:998	density	992:998	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	18	theme	films	1063:1067	arg1	water-tightness					1001:1015	water-tightness	1001:1015	water-tightness	1001:1015	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	18	theme	films	1063:1067	arg1	FTIR					1055:1058	FTIR	1055:1058	FTIR	1055:1058	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	6	18	theme	films	1063:1067	arg1	thickness					981:989	thickness	981:989	thickness	981:989	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	0	19	theme	Tunable	0:6	arg1	behavior					19:26	Tunable mechanical behavior	0:26	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.	0:103	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	1	20	theme	cellulose	238:246	arg1	CNF					259:261	CNF	259:261	CNF	259:261	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	20	theme	cellulose	238:246	arg1	nanofiber					248:256	cellulose nanofiber	238:256	cellulose nanofiber (CNF)	238:262	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	3	21	theme	intercrystalline	518:533	arg1	fracture					535:542	intercrystalline fracture	518:542	intercrystalline fracture	518:542	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	4	22	dep	%	798:798	arg1	to					800:801	to	800:801	to	800:801	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	3	23	theme	abundant	559:566	arg1	bonding					577:583	the abundant hydrogen bonding	555:583	the abundant hydrogen bonding	555:583	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	4	24	theme	CF	718:719	arg1	slippage					706:713	the interfibrillar slippage	687:713	the interfibrillar slippage of CF	687:719	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	3	25	theme	collagen	431:438	arg1	67.5 MPa					446:453	67.5 MPa	446:453	67.5 MPa	446:453	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	3	25	theme	collagen	431:438	arg1	film					440:443	collagen film	431:443	collagen film (67.5 MPa)	431:454	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	4	26	theme	interfibrillar	691:704	arg1	slippage					706:713	the interfibrillar slippage	687:713	the interfibrillar slippage of CF	687:719	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	1	27	theme	Collagen	105:112	arg1	films					120:124	Collagen (Col) films	105:124	Collagen (Col) films	105:124	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	3	28	theme	film	440:443	arg1	stress					421:426	the fracture stress	408:426	the fracture stress of collagen film (67.5 MPa)	408:454	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	0	29	theme	films	46:50	arg1	behavior					19:26	Tunable mechanical behavior	0:26	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.	0:103	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	4	30	dep	pull-off	725:732	arg1	improving					759:767	improving	759:767	improving the strain-to-break from 8.37% to 12.13%	759:808	The toughness of Col-CF films was increased by the interfibrillar slippage of CF and pull-off of CF within the matrix, improving the strain-to-break from 8.37% to 12.13%.					
35661672	0	31	theme	collagen-based	31:44	arg1	films					46:50	collagen-based films	31:50	collagen-based films	31:50	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	3	32	theme	mechanical	589:598	arg1	locking					600:606	mechanical locking	589:606	mechanical locking	589:606	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	7	33	with	film	1228:1231	arg1	properties					1260:1269	adjustable mechanical properties	1238:1269	adjustable mechanical properties	1238:1269	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35661672	0	34	from	comparison	55:64	arg1	geometries					93:102	different geometries	83:102	different geometries	83:102	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	7	35	theme	collagen	1186:1193	arg1	film					1195:1198	collagen film	1186:1198	collagen film offering strategies for the film with adjustable mechanical properties	1186:1269	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35661672	1	36	theme	cellulose	268:276	arg1	CNC					292:294	CNC	292:294	CNC	292:294	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	36	theme	cellulose	268:276	arg1	nanocrystals					278:289	cellulose nanocrystals	268:289	cellulose nanocrystals (CNC)	268:295	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	6	37	dep	thickness	981:989	arg1	the					977:979	the	977:979	the	977:979	Besides, the effects of celluloses' geometries on the thickness, density, water-tightness, thermal stability, crystallinity and FTIR of films were also investigated.					
35661672	7	38	theme	mechanical	1249:1258	arg1	properties					1260:1269	adjustable mechanical properties	1238:1269	adjustable mechanical properties	1238:1269	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35661672	7	39	theme	film	1195:1198	arg1	behaviors					1173:1181	the behaviors	1169:1181	the behaviors of collagen film offering strategies for the film with adjustable mechanical properties	1169:1269	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35661672	0	40	dep	behavior	19:26	arg1	comparison					55:64	A comparison	53:64	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.	0:103	Tunable mechanical behavior of collagen-based films: A comparison of celluloses in different geometries.					
35661672	5	41	theme	mechanical	855:864	arg1	behavior					866:873	the mechanical behavior	851:873	the mechanical behavior	851:873	The films added with MCC and CNC weaken the mechanical behavior, due to the defects and lack of mechanical locking.					
35661672	2	42	dep	elastoplasticity	352:367	arg1	the					348:350	the	348:350	the	348:350	The reinforcement mechanisms were investigated by the elastoplasticity and fracture appearance.					
35661672	2	42	dep	elastoplasticity	352:367	arg1	appearance					382:391	appearance	382:391	appearance	382:391	The reinforcement mechanisms were investigated by the elastoplasticity and fracture appearance.					
35661672	1	43	theme	microcrystalline	181:196	arg1	cellulose					198:206	microcrystalline cellulose	181:206	microcrystalline cellulose (MCC)	181:212	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	43	theme	microcrystalline	181:196	arg1	MCC					209:211	MCC	209:211	MCC	209:211	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	3	44	theme	fracture	412:419	arg1	stress					421:426	the fracture stress	408:426	the fracture stress of collagen film (67.5 MPa)	408:454	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	1	45	theme	cellulosic	215:224	arg1	CF					233:234	CF	233:234	CF	233:234	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	1	45	theme	cellulosic	215:224	arg1	fines					226:230	cellulosic fines	215:230	cellulosic fines (CF)	215:235	Collagen (Col) films were reinforced by celluloses in different geometries: microcrystalline cellulose (MCC), cellulosic fines (CF), cellulose nanofiber (CNF) and cellulose nanocrystals (CNC).					
35661672	3	46	theme	hydrogen	568:575	arg1	bonding					577:583	the abundant hydrogen bonding	555:583	the abundant hydrogen bonding	555:583	Compared with the fracture stress of collagen film (67.5 MPa), the Col-CNF films effectively borne the stress (95.8 MPa) by intercrystalline fracture, ascribing the abundant hydrogen bonding and mechanical locking between cellulose and collagen.					
35661672	7	47	theme	fillers	1143:1149	arg1	geometries					1129:1138	the geometries	1125:1138	the geometries of fillers	1125:1149	These provide the evidence that the geometries of fillers diversely improve the behaviors of collagen film offering strategies for the film with adjustable mechanical properties.					
35231535	1	0	theme	polymer	147:153	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	0	theme	polymer	147:153	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	0	1	theme	glucose	90:96	arg1	sensor					98:103	non-enzymatic electrochemical glucose sensor	60:103	non-enzymatic electrochemical glucose sensor	60:103	Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor.					
35231535	1	2	theme	matrix-derived	155:168	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	2	theme	matrix-derived	155:168	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	3	theme	low-cost	252:259	arg1	complex					268:274	a low-cost copper complex	250:274	a low-cost copper complex of chitosan polymer	250:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	3	4	theme	glucose	391:397	arg1	sensor					399:404	The glucose sensor	387:404	The glucose sensor	387:404	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	4	5	theme	real	711:714	arg1	sample					716:721	real sample	711:721	real sample in human serum	711:736	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	1	6	theme	copper	261:266	arg1	complex					268:274	a low-cost copper complex	250:274	a low-cost copper complex of chitosan polymer	250:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	5	7	from	detection	880:888	arg1	fluids					904:909	biological fluids	893:909	biological fluids	893:909	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	5	8	theme	biological	893:902	arg1	fluids					904:909	biological fluids	893:909	biological fluids	893:909	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	4	9	from	sample	716:721	arg1	serum					732:736	human serum	726:736	human serum	726:736	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	3	10	theme	low	456:458	arg1	limit					470:474	a low detection limit 2.72 μM	454:482	a low detection limit 2.72 μM	454:482	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	5	11	theme	efficient	783:791	arg1	material					807:814	an efficient nanocomposite material	780:814	an efficient nanocomposite material for non-enzymatic glucose sensors	780:848	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	5	11	theme	efficient	783:791	arg1	CuS/NSC					769:775	CuS/NSC	769:775	CuS/NSC	769:775	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	4	12	theme	interfering	637:647	arg1	agents					649:654	potential interfering agents	627:654	potential interfering agents	627:654	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	3	13	theme	detection	460:468	arg1	limit					470:474	a low detection limit 2.72 μM	454:482	a low detection limit 2.72 μM	454:482	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	3	14	theme	linear	418:423	arg1	range					425:429	a linear range	416:429	a linear range of 160 μM to 11.76 mM	416:451	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	5	15	theme	non-enzymatic	820:832	arg1	sensors					842:848	non-enzymatic glucose sensors	820:848	non-enzymatic glucose sensors	820:848	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	5	16	theme	nanocomposite	793:805	arg1	material					807:814	an efficient nanocomposite material	780:814	an efficient nanocomposite material for non-enzymatic glucose sensors	780:848	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	5	16	theme	nanocomposite	793:805	arg1	CuS/NSC					769:775	CuS/NSC	769:775	CuS/NSC	769:775	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	0	17	theme	Chitosan	0:7	arg1	polymer					9:15	Chitosan polymer	0:15	Chitosan polymer	0:15	Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor.					
35231535	3	18	dep	11.76 mM	444:451	arg1	to					441:442	to	441:442	to	441:442	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	5	19	theme	glucose	872:878	arg1	detection					880:888	glucose detection	872:888	glucose detection in biological fluids	872:909	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	1	20	theme	chitosan	279:286	arg1	polymer					288:294	chitosan polymer	279:294	chitosan polymer	279:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	4	21	theme	satisfactory	672:683	arg1	percentage					694:703	a satisfactory recovery percentage	670:703	a satisfactory recovery percentage using real sample in human serum	670:736	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	1	22	theme	polymer	288:294	arg1	complex					268:274	a low-cost copper complex	250:274	a low-cost copper complex of chitosan polymer	250:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	23	link	matrix-derived	155:168	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	23	link	matrix-derived	155:168	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	2	24	theme	Cyclic	297:302	arg1	voltammetry					304:314	Cyclic voltammetry	297:314	Cyclic voltammetry	297:314	Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance.					
35231535	3	25	theme	linear	542:547	arg1	response					549:556	an excellent linear response	529:556	an excellent linear response	529:556	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	5	26	theme	glucose	834:840	arg1	sensors					842:848	non-enzymatic glucose sensors	820:848	non-enzymatic glucose sensors	820:848	The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.					
35231535	3	27	theme	11.76 mM	444:451	arg1	sensitivity					490:500	a sensitivity	488:500	a sensitivity of 13.62 mA mM-1 cm-2	488:522	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	3	27	theme	11.76 mM	444:451	arg1	range					425:429	a linear range	416:429	a linear range of 160 μM to 11.76 mM	416:451	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	3	27	theme	11.76 mM	444:451	arg1	limit					470:474	a low detection limit 2.72 μM	454:482	a low detection limit 2.72 μM	454:482	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	4	28	theme	recovery	685:692	arg1	percentage					694:703	a satisfactory recovery percentage	670:703	a satisfactory recovery percentage using real sample in human serum	670:736	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	3	29	theme	13.62 mA mM-1 cm-2	505:522	arg1	sensitivity					490:500	a sensitivity	488:500	a sensitivity of 13.62 mA mM-1 cm-2	488:522	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	3	29	theme	13.62 mA mM-1 cm-2	505:522	arg1	range					425:429	a linear range	416:429	a linear range of 160 μM to 11.76 mM	416:451	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	3	29	theme	13.62 mA mM-1 cm-2	505:522	arg1	limit					470:474	a low detection limit 2.72 μM	454:482	a low detection limit 2.72 μM	454:482	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	4	30	theme	potential	627:635	arg1	agents					649:654	potential interfering agents	627:654	potential interfering agents	627:654	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	3	31	theme	excellent	532:540	arg1	response					549:556	an excellent linear response	529:556	an excellent linear response	529:556	The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM-1 cm-2 with an excellent linear response.					
35231535	2	32	theme	electrocatalytic	357:372	arg1	performance					374:384	excellent electrocatalytic performance	347:384	excellent electrocatalytic performance	347:384	Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance.					
35231535	4	33	theme	human	726:730	arg1	serum					732:736	human serum	726:736	human serum	726:736	Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum.					
35231535	2	34	theme	excellent	347:355	arg1	performance					374:384	excellent electrocatalytic performance	347:384	excellent electrocatalytic performance	347:384	Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance.					
35231535	1	35	theme	one-step	212:219	arg1	technique					234:242	a one-step hydrothermal technique	210:242	a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer	210:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	36	theme	S	127:127	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	36	theme	S	127:127	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	37	theme	hydrothermal	221:232	arg1	technique					234:242	a one-step hydrothermal technique	210:242	a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer	210:294	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	0	38	theme	electrochemical	74:88	arg1	sensor					98:103	non-enzymatic electrochemical glucose sensor	60:103	non-enzymatic electrochemical glucose sensor	60:103	Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor.					
35231535	1	39	theme	co-doped	129:136	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	39	theme	co-doped	129:136	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	0	40	theme	non-enzymatic	60:72	arg1	sensor					98:103	non-enzymatic electrochemical glucose sensor	60:103	non-enzymatic electrochemical glucose sensor	60:103	Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor.					
35231535	1	41	theme	chitosan	138:145	arg1	CuS/NSC					181:187	CuS/NSC	181:187	CuS/NSC	181:187	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35231535	1	41	theme	chitosan	138:145	arg1	composite					170:178	S co-doped chitosan polymer matrix-derived composite	127:178	S co-doped chitosan polymer matrix-derived composite (CuS/NSC)	127:188	In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer.					
35108002	7	0	theme	high	1072:1075	arg1	concentrations					1077:1090	high concentrations	1072:1090	high concentrations of TF-3	1072:1098	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	1	1	theme	hydrophilic	207:217	arg1	polyphenols					219:229	many hydrophilic polyphenols	202:229	many hydrophilic polyphenols	202:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	5	2	theme	high	836:839	arg1	efficiency					855:864	high encapsulation efficiency	836:864	high encapsulation efficiency	836:864	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	7	3	theme	nanocomplexes	1053:1065	arg1	structure					1033:1041	the globular unit structure	1015:1041	the globular unit structure of CS-CPP nanocomplexes	1015:1065	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	1	4	theme	polyphenols	219:229	arg1	bioavailability					183:197	the bioavailability	179:197	the bioavailability of many hydrophilic polyphenols	179:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	8	5	theme	CS-CPP	1252:1257	arg1	nanocomplexes					1259:1271	the CS-CPP nanocomplexes	1248:1271	the CS-CPP nanocomplexes	1248:1271	Importantly, as proved using the Caco-2 monolayer model, the intestinal permeability of TF-3 was significantly enhanced by the CS-CPP nanocomplexes.					
35108002	6	6	theme	Microstructural	888:902	arg1	studies					904:910	Microstructural studies	888:910	Microstructural studies	888:910	Microstructural studies showed strong intermolecular associations between CS, CPPs, and TF-3.					
35108002	1	7	theme	Low	113:115	arg1	permeability					128:139	Low intestinal permeability	113:139	Low intestinal permeability	113:139	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	1	7	theme	Low	113:115	arg1	feature					159:165	an unfavorable feature	144:165	an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols	144:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	3	8	theme	electrostatic	607:619	arg1	force					650:654	the dominant force	637:654	the dominant force	637:654	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	3	8	theme	electrostatic	607:619	arg1	interaction					621:631	electrostatic interaction	607:631	electrostatic interaction	607:631	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	2	9	with	tea	437:439	arg1	permeability					462:473	poor intestinal permeability	446:473	poor intestinal permeability	446:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	4	10	theme	ζ	678:678	arg1	potentials					680:689	ζ potentials	678:689	ζ potentials	678:689	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	1	11	theme	intestinal	117:126	arg1	permeability					128:139	Low intestinal permeability	113:139	Low intestinal permeability	113:139	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	1	11	theme	intestinal	117:126	arg1	feature					159:165	an unfavorable feature	144:165	an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols	144:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	2	12	theme	black	431:435	arg1	tea					437:439	black tea	431:439	black tea with poor intestinal permeability	431:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	7	13	theme	unit	1028:1031	arg1	structure					1033:1041	the globular unit structure	1015:1041	the globular unit structure of CS-CPP nanocomplexes	1015:1065	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	4	14	theme	nanocomplexes	701:713	arg1	PDIs					668:671	PDIs	668:671	PDIs	668:671	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	4	14	theme	nanocomplexes	701:713	arg1	sizes					661:665	sizes	661:665	sizes	661:665	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	4	14	theme	nanocomplexes	701:713	arg1	potentials					680:689	ζ potentials	678:689	ζ potentials	678:689	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	0	15	theme	Intestinal	10:19	arg1	Permeability					21:32	Intestinal Permeability	10:32	Intestinal Permeability of Theaflavin-3,3'-digallate by Chitosan-Caseinophosphopeptides Nanocomplexes	10:110	Enhancing Intestinal Permeability of Theaflavin-3,3'-digallate by Chitosan-Caseinophosphopeptides Nanocomplexes.					
35108002	8	16	theme	Caco-2	1158:1163	arg1	model					1175:1179	the Caco-2 monolayer model	1154:1179	the Caco-2 monolayer model	1154:1179	Importantly, as proved using the Caco-2 monolayer model, the intestinal permeability of TF-3 was significantly enhanced by the CS-CPP nanocomplexes.					
35108002	2	17	theme	intestinal	339:348	arg1	permeability					350:361	the intestinal permeability	335:361	the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability	335:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	3	18	theme	dominant	641:648	arg1	force					650:654	the dominant force	637:654	the dominant force	637:654	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	3	18	theme	dominant	641:648	arg1	interaction					621:631	electrostatic interaction	607:631	electrostatic interaction	607:631	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	2	19	theme	characteristic	402:415	arg1	theaflavin-3,3'-digallate					366:390	theaflavin-3,3'-digallate	366:390	theaflavin-3,3'-digallate (TF-3)	366:397	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	2	19	theme	characteristic	402:415	arg1	polyphenol					417:426	a characteristic polyphenol	400:426	a characteristic polyphenol in black tea with poor intestinal permeability	400:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	5	20	theme	CS-CPP	761:766	arg1	nanocomplex					768:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	7	21	theme	globular	1019:1026	arg1	structure					1033:1041	the globular unit structure	1015:1041	the globular unit structure of CS-CPP nanocomplexes	1015:1065	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	1	22	theme	unfavorable	147:157	arg1	permeability					128:139	Low intestinal permeability	113:139	Low intestinal permeability	113:139	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	1	22	theme	unfavorable	147:157	arg1	feature					159:165	an unfavorable feature	144:165	an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols	144:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
35108002	2	23	theme	intestinal	451:460	arg1	permeability					462:473	poor intestinal permeability	446:473	poor intestinal permeability	446:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	8	24	theme	monolayer	1165:1173	arg1	model					1175:1179	the Caco-2 monolayer model	1154:1179	the Caco-2 monolayer model	1154:1179	Importantly, as proved using the Caco-2 monolayer model, the intestinal permeability of TF-3 was significantly enhanced by the CS-CPP nanocomplexes.					
35108002	4	25	dep	sizes	661:665	arg1	The					657:659	The	657:659	The	657:659	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	2	26	used	used	265:268	arg2	CS					257:258	CS	257:258	CS	257:258	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	2	26	used	used	265:268	arg2	chitosan					247:254	chitosan	247:254	chitosan (CS)	247:259	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	2	27	theme	poor	446:449	arg1	permeability					462:473	poor intestinal permeability	446:473	poor intestinal permeability	446:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	5	28	theme	encapsulation	841:853	arg1	efficiency					855:864	high encapsulation efficiency	836:864	high encapsulation efficiency	836:864	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	3	29	theme	turbidimetric	542:554	arg1	titration					556:564	turbidimetric titration	542:564	turbidimetric titration	542:564	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	7	30	theme	CS-CPP	1046:1051	arg1	nanocomplexes					1053:1065	CS-CPP nanocomplexes	1046:1065	CS-CPP nanocomplexes	1046:1065	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	4	31	theme	CS-CPP	694:699	arg1	nanocomplexes					701:713	CS-CPP nanocomplexes	694:713	CS-CPP nanocomplexes	694:713	The sizes, PDIs, and ζ potentials of CS-CPP nanocomplexes varied with their compositions.					
35108002	0	32	theme	Theaflavin-3,3'-digallate	37:61	arg1	Permeability					21:32	Intestinal Permeability	10:32	Intestinal Permeability of Theaflavin-3,3'-digallate by Chitosan-Caseinophosphopeptides Nanocomplexes	10:110	Enhancing Intestinal Permeability of Theaflavin-3,3'-digallate by Chitosan-Caseinophosphopeptides Nanocomplexes.					
35108002	2	33	from	polyphenol	417:426	arg1	tea					437:439	black tea	431:439	black tea with poor intestinal permeability	431:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	2	34	with	complex	273:279	arg1	CPPs					310:313	CPPs	310:313	CPPs	310:313	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	2	34	with	complex	273:279	arg1	caseinophosphopeptides					286:307	caseinophosphopeptides	286:307	caseinophosphopeptides (CPPs)	286:314	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	5	35	theme	low	870:872	arg1	cytotoxicity					874:885	low cytotoxicity	870:885	low cytotoxicity	870:885	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	5	36	used	used	797:800	arg2	nanocomplex					768:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	8	37	theme	intestinal	1186:1195	arg1	permeability					1197:1208	the intestinal permeability	1182:1208	the intestinal permeability of TF-3	1182:1216	Importantly, as proved using the Caco-2 monolayer model, the intestinal permeability of TF-3 was significantly enhanced by the CS-CPP nanocomplexes.					
35108002	7	38	theme	TF-3	1095:1098	arg1	concentrations					1077:1090	high concentrations	1072:1090	high concentrations of TF-3	1072:1098	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	2	39	theme	theaflavin-3,3'-digallate	366:390	arg1	permeability					350:361	the intestinal permeability	335:361	the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability	335:473	In this study, chitosan (CS) was used to complex with caseinophosphopeptides (CPPs), aiming to improve the intestinal permeability of theaflavin-3,3'-digallate (TF-3), a characteristic polyphenol in black tea with poor intestinal permeability.					
35108002	7	40	theme	TF-3	999:1002	arg1	Encapsulation					982:994	Encapsulation	982:994	Encapsulation of TF-3	982:1002	Encapsulation of TF-3 maintained the globular unit structure of CS-CPP nanocomplexes, but high concentrations of TF-3 resulted in aggregation.					
35108002	8	41	theme	TF-3	1213:1216	arg1	permeability					1197:1208	the intestinal permeability	1182:1208	the intestinal permeability of TF-3	1182:1216	Importantly, as proved using the Caco-2 monolayer model, the intestinal permeability of TF-3 was significantly enhanced by the CS-CPP nanocomplexes.					
35108002	6	42	theme	intermolecular	926:939	arg1	associations					941:952	strong intermolecular associations	919:952	strong intermolecular associations between CS, CPPs, and TF-3	919:979	Microstructural studies showed strong intermolecular associations between CS, CPPs, and TF-3.					
35108002	5	43	theme	optimized	751:759	arg1	nanocomplex					768:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex	747:778	The optimized CS-CPP nanocomplex was subsequently used to encapsulate TF-3, which showed high encapsulation efficiency and low cytotoxicity.					
35108002	6	44	theme	strong	919:924	arg1	associations					941:952	strong intermolecular associations	919:952	strong intermolecular associations between CS, CPPs, and TF-3	919:979	Microstructural studies showed strong intermolecular associations between CS, CPPs, and TF-3.					
35108002	3	45	theme	various	572:578	arg1	conditions					580:589	various conditions	572:589	various conditions	572:589	Complexation between CS and CPPs was systemically investigated by turbidimetric titration under various conditions, revealing that electrostatic interaction was the dominant force.					
35108002	1	46	theme	many	202:205	arg1	polyphenols					219:229	many hydrophilic polyphenols	202:229	many hydrophilic polyphenols	202:229	Low intestinal permeability is an unfavorable feature that limits the bioavailability of many hydrophilic polyphenols.					
36257362	0	0	theme	composite	90:98	arg1	hydrogel					100:107	composite hydrogel	90:107	composite hydrogel with fast self-healing nature	90:137	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	1	1	theme	smart	157:161	arg1	hydrogel					217:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel	155:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel"	155:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	4	2	theme	nature	622:627	arg1	advantage					601:609	the advantage	597:609	the advantage of dynamic nature of covalent and non-covalent interactions	597:669	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	5	3	theme	thixotropic	823:833	arg1	response					835:842	thixotropic response	823:842	thixotropic response	823:842	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	1	4	theme	Chitosan-isophthalaldehyde-Graphene	163:197	arg1	hydrogel					217:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel	155:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel"	155:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	4	5	theme	dynamic	614:620	arg1	nature					622:627	dynamic nature	614:627	dynamic nature of covalent and non-covalent interactions	614:669	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	12	6	with	purpose	1502:1508	arg1	toxicity					1519:1526	low toxicity	1515:1526	low toxicity	1515:1526	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	6	7	theme	recorded	954:961	arg1	videos					963:968	The recorded videos	950:968	The recorded videos	950:968	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	3	8	dep	The	508:510	arg1	GO					512:513	GO	512:513	GO	512:513	The GO provides physical crosslinks and antibacterial properties to the hydrogel.					
36257362	4	9	theme	covalent	632:639	arg1	interactions					658:669	covalent and non-covalent interactions	632:669	covalent and non-covalent interactions	632:669	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	5	10	theme	hydrogels	777:785	arg1	self-healing					761:772	Further self-healing	753:772	Further self-healing of hydrogels	753:785	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	4	11	theme	pH	741:742	arg1	changes					744:750	the pH changes	737:750	the pH changes	737:750	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	6	12	theme	2-6 min	1029:1035	arg1	frame					1020:1024	a time frame	1013:1024	a time frame of 2-6 min	1013:1035	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	0	13	theme	self-healing	119:130	arg1	nature					132:137	fast self-healing nature	114:137	fast self-healing nature	114:137	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	2	14	theme	responsive	291:300	arg1	changes					302:308	an unprecedented pH responsive changes	271:308	an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability	271:393	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	4	15	from	stretchability	707:720	arg1	response					725:732	response	725:732	response to the pH changes	725:750	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	1	16	theme	oxide	199:203	arg1	hydrogel					217:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel	155:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel"	155:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	0	17	theme	fast	114:117	arg1	nature					132:137	fast self-healing nature	114:137	fast self-healing nature	114:137	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	9	18	theme	hydrogel	1256:1263	arg1	characterization					1236:1251	The characterization	1232:1251	The characterization of hydrogel	1232:1263	The characterization of hydrogel was carried by FTIR, FESEM and TGA analysis.					
36257362	2	19	theme	pH	288:289	arg1	changes					302:308	an unprecedented pH responsive changes	271:308	an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability	271:393	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	5	20	theme	imaging	910:916	arg1	techniques					938:947	real time optical imaging and video recording techniques	892:947	real time optical imaging and video recording techniques	892:947	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	12	21	theme	reduced	1444:1450	arg1	hydrogel					1452:1459	The reduced hydrogel	1440:1459	The reduced hydrogel	1440:1459	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	4	22	from	adhesion	694:701	arg1	response					725:732	response	725:732	response to the pH changes	725:750	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	1	23	theme	CS-ISD-GO	206:214	arg1	hydrogel					217:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel	155:224	a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel"	155:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	12	24	theme	release	1494:1500	arg1	purpose					1502:1508	drug release purpose	1489:1508	drug release purpose with low toxicity	1489:1526	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	12	25	theme	drug	1489:1492	arg1	purpose					1502:1508	drug release purpose	1489:1508	drug release purpose with low toxicity	1489:1526	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	11	26	theme	lower	1418:1422	arg1	values					1427:1432	lower pH values	1418:1432	lower pH values	1418:1432	The reduced gel appears to be stable at lower pH values also.					
36257362	5	27	theme	video	922:926	arg1	recording					928:936	video recording	922:936	video recording	922:936	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	8	28	theme	subsequent	1205:1214	arg1	disintegration					1216:1229	subsequent disintegration	1205:1229	subsequent disintegration	1205:1229	The hydrogel becomes mechanically strong above pH 5.5 and becomes unstable above pH 7 leading to subsequent disintegration.					
36257362	0	29	with	hydrogel	100:107	arg1	nature					132:137	fast self-healing nature	114:137	fast self-healing nature	114:137	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	5	30	theme	sweep	882:886	arg1	cycles					865:870	more than three cycles	849:870	more than three cycles of strain sweep	849:886	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	5	30	theme	sweep	882:886	arg1	techniques					938:947	real time optical imaging and video recording techniques	892:947	real time optical imaging and video recording techniques	892:947	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	0	31	theme	rheological	12:22	arg1	features					24:31	rheological features	12:31	rheological features of strain and pH sensitive chitosan-imine	12:73	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	6	32	theme	time	1015:1018	arg1	frame					1020:1024	a time frame	1013:1024	a time frame of 2-6 min	1013:1035	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	12	33	theme	low	1515:1517	arg1	toxicity					1519:1526	low toxicity	1515:1526	low toxicity	1515:1526	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	2	34	theme	ISD	444:446	arg1	concentration					420:432	concentration	420:432	concentration	420:432	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	34	theme	ISD	444:446	arg1	pH					413:414	pH	413:414	pH	413:414	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	0	35	theme	strain	36:41	arg1	Texture					0:6	Texture	0:6	Texture	0:6	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	0	35	theme	strain	36:41	arg1	features					24:31	rheological features	12:31	rheological features of strain and pH sensitive chitosan-imine	12:73	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	5	36	theme	Further	753:759	arg1	self-healing					761:772	Further self-healing	753:772	Further self-healing of hydrogels	753:785	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	5	37	theme	real	892:895	arg1	imaging					910:916	real time optical imaging	892:916	real time optical imaging	892:916	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	4	38	theme	hydrogel	685:692	arg1	adhesion					694:701	hydrogel adhesion	685:701	hydrogel adhesion	685:701	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	5	39	theme	optical	902:908	arg1	imaging					910:916	real time optical imaging	892:916	real time optical imaging	892:916	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	11	40	from	values	1427:1432	arg1	stable					1408:1413	stable	1408:1413	stable	1408:1413	The reduced gel appears to be stable at lower pH values also.					
36257362	11	41	theme	pH	1424:1425	arg1	values					1427:1432	lower pH values	1418:1432	lower pH values	1418:1432	The reduced gel appears to be stable at lower pH values also.					
36257362	2	42	theme	CS	437:438	arg1	concentration					420:432	concentration	420:432	concentration	420:432	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	42	theme	CS	437:438	arg1	pH					413:414	pH	413:414	pH	413:414	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	43	theme	rheological	486:496	arg1	analysis					498:505	rheological analysis	486:505	rheological analysis	486:505	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	5	44	theme	recording	928:936	arg1	techniques					938:947	real time optical imaging and video recording techniques	892:947	real time optical imaging and video recording techniques	892:947	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	5	45	theme	strain	875:880	arg1	sweep					882:886	strain sweep	875:886	strain sweep	875:886	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	11	46	theme	reduced	1382:1388	arg1	gel					1390:1392	The reduced gel	1378:1392	The reduced gel	1378:1392	The reduced gel appears to be stable at lower pH values also.					
36257362	6	47	theme	self-healing	984:995	arg1	response					997:1004	100 % self-healing response	978:1004	100 % self-healing response	978:1004	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	7	48	theme	pH	1094:1095	arg1	range					1085:1089	small range	1079:1089	small range of pH (4.5-5.5)	1079:1105	These properties were observed only over small range of pH (4.5-5.5).					
36257362	9	49	theme	TGA	1296:1298	arg1	analysis					1300:1307	TGA analysis	1296:1307	TGA analysis	1296:1307	The characterization of hydrogel was carried by FTIR, FESEM and TGA analysis.					
36257362	10	50	theme	drug	1364:1367	arg1	release					1369:1375	drug release	1364:1375	drug release	1364:1375	In addition, the hydrogel was reduced using NaBH4 for drug release.					
36257362	3	51	theme	physical	524:531	arg1	crosslinks					533:542	physical crosslinks	524:542	physical crosslinks	524:542	The GO provides physical crosslinks and antibacterial properties to the hydrogel.					
36257362	6	52	theme	%	982:982	arg1	response					997:1004	100 % self-healing response	978:1004	100 % self-healing response	978:1004	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	7	53	theme	small	1079:1083	arg1	range					1085:1089	small range	1079:1089	small range of pH (4.5-5.5)	1079:1105	These properties were observed only over small range of pH (4.5-5.5).					
36257362	2	54	theme	unprecedented	274:286	arg1	changes					302:308	an unprecedented pH responsive changes	271:308	an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability	271:393	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	12	55	used	used	1480:1483	arg2	hydrogel					1452:1459	The reduced hydrogel	1440:1459	The reduced hydrogel	1440:1459	The reduced hydrogel may potentially be used for drug release purpose with low toxicity.					
36257362	1	56	theme	multicomponent	232:245	arg1	"					255:255	a "multicomponent hydrogel"	229:255	a "multicomponent hydrogel"	229:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	2	57	dep	pH	413:414	arg1	the					409:411	the	409:411	the	409:411	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	1	58	theme	hydrogel	247:254	arg1	"					255:255	a "multicomponent hydrogel"	229:255	a "multicomponent hydrogel"	229:255	Here we report a smart Chitosan-isophthalaldehyde-Graphene oxide (CS-ISD-GO) hydrogel as a "multicomponent hydrogel".					
36257362	0	59	theme	chitosan-imine	60:73	arg1	Texture					0:6	Texture	0:6	Texture	0:6	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	0	59	theme	chitosan-imine	60:73	arg1	features					24:31	rheological features	12:31	rheological features of strain and pH sensitive chitosan-imine	12:73	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	5	60	theme	time	897:900	arg1	imaging					910:916	real time optical imaging	892:916	real time optical imaging	892:916	Further self-healing of hydrogels was fully investigated by measuring thixotropic response over more than three cycles of strain sweep and real time optical imaging and video recording techniques.					
36257362	3	61	theme	antibacterial	548:560	arg1	properties					562:571	antibacterial properties	548:571	antibacterial properties	548:571	The GO provides physical crosslinks and antibacterial properties to the hydrogel.					
36257362	2	62	from	changes	302:308	arg1	self-healing					360:371	self-healing	360:371	self-healing	360:371	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	62	from	changes	302:308	arg1	adhesiveness					346:357	adhesiveness	346:357	adhesiveness	346:357	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	62	from	changes	302:308	arg1	stretchability					330:343	stretchability	330:343	stretchability	330:343	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	62	from	changes	302:308	arg1	viscoelasticity					313:327	viscoelasticity	313:327	viscoelasticity	313:327	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	2	62	from	changes	302:308	arg1	self-adaptability					377:393	self-adaptability	377:393	self-adaptability	377:393	We witnessed an unprecedented pH responsive changes in viscoelasticity, stretchability, adhesiveness, self-healing and self-adaptability upon changing the pH and concentration of CS and ISD that was authenticated by texture and rheological analysis.					
36257362	0	63	theme	sensitive	50:58	arg1	chitosan-imine					60:73	pH sensitive chitosan-imine	47:73	pH sensitive chitosan-imine	47:73	Texture and rheological features of strain and pH sensitive chitosan-imine graphene-oxide composite hydrogel with fast self-healing nature.					
36257362	6	64	theme	100 	978:981	arg1	%					982:982	%	982:982	%	982:982	The recorded videos display 100 % self-healing response within a time frame of 2-6 min.					
36257362	4	65	dep	adhesion	694:701	arg1	the					681:683	the	681:683	the	681:683	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	4	66	theme	non-covalent	645:656	arg1	interactions					658:669	covalent and non-covalent interactions	632:669	covalent and non-covalent interactions	632:669	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36257362	4	67	theme	interactions	658:669	arg1	nature					622:627	dynamic nature	614:627	dynamic nature of covalent and non-covalent interactions	614:669	Taking the advantage of dynamic nature of covalent and non-covalent interactions, we tuned the hydrogel adhesion and stretchability in response to the pH changes.					
36048570	0	0	theme	Flexible	71:78	arg1	Microchips					91:100	Flexible Biosensing Microchips	71:100	Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring	71:158	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	6	1	theme	detection	1250:1258	arg1	limit					1260:1264	a low detection limit	1244:1264	a low detection limit	1244:1264	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	4	2	theme	@	847:847	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	2	theme	@	847:847	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	3	theme	ultrasensitive	682:695	arg1	microchip					707:715	an ultrasensitive biosensor microchip	679:715	an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s	679:771	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	4	theme	PBA	844:846	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	4	theme	PBA	844:846	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	2	5	theme	key	360:362	arg1	role					364:367	a key role	358:367	a key role of a protective agent	358:389	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	6	6	theme	sucrose	1282:1288	arg1	recognition					1290:1300	the accurate sucrose recognition	1269:1300	the accurate sucrose recognition	1269:1300	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	5	7	theme	certain	984:990	arg1	plane					992:996	a certain plane	982:996	a certain plane to create more regular and continuous edge features	982:1048	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	7	8	theme	as-prepared	1361:1371	arg1	microchip					1373:1381	the as-prepared microchip	1357:1381	the as-prepared microchip	1357:1381	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	3	9	theme	sucrose	530:536	arg1	detection					517:525	rapid and precise detection	499:525	rapid and precise detection of sucrose	499:536	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	7	10	theme	novel	1550:1554	arg1	strategy					1567:1574	a novel analytical strategy	1548:1574	a novel analytical strategy for the binary mixture substrate system	1548:1614	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	0	11	theme	Biosensing	80:89	arg1	Microchips					91:100	Flexible Biosensing Microchips	71:100	Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring	71:158	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	5	12	theme	PBA	955:957	arg1	crystallization					959:973	the oriented PBA crystallization	942:973	the oriented PBA crystallization	942:973	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	1	13	theme	microbial	271:279	arg1	metabolism					281:290	the microbial metabolism	267:290	the microbial metabolism with its concentration fluctuation	267:325	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	0	14	theme	Ultrasensitive	113:126	arg1	Monitoring					149:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	4	15	theme	Au	830:831	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	15	theme	Au	830:831	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	7	16	theme	analytical	1556:1565	arg1	strategy					1567:1574	a novel analytical strategy	1548:1574	a novel analytical strategy for the binary mixture substrate system	1548:1614	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	7	17	theme	sucrose	1419:1425	arg1	concentrations					1439:1452	the sucrose and glucose concentrations	1415:1452	concentrations	1439:1452	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	2	18	theme	agent	385:389	arg1	role					364:367	a key role	358:367	a key role of a protective agent	358:389	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	4	19	theme	above	654:658	arg1	issue					660:664	the above issue	650:664	the above issue	650:664	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	2	20	theme	new	451:453	arg1	vaccines					460:467	the new mRNA vaccines	447:467	the new mRNA vaccines for curing COVID-19	447:487	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	5	21	theme	special	878:884	arg1	structure					896:904	This special geometric structure	873:904	This special geometric structure	873:904	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	4	22	theme	@	829:829	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	22	theme	@	829:829	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	6	23	theme	biosensor	1165:1173	arg1	microchip					1175:1183	an enzymatic biosensor microchip	1152:1183	an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition	1152:1300	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	3	24	from	research	620:627	arg1	desired					548:554	desired	548:554	desired	548:554	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	1	25	theme	most	183:186	arg1	sources					203:209	the most applied carbon sources	179:209	the most applied carbon sources in the fermentation process	179:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	7	26	theme	outstanding	1459:1469	arg1	reusability					1471:1481	outstanding reusability	1459:1481	outstanding reusability (more than 300 times)	1459:1503	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	7	26	theme	outstanding	1459:1469	arg1	times					1498:1502	more than 300 times	1484:1502	more than 300 times	1484:1502	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	6	27	theme	low	1246:1248	arg1	limit					1260:1264	a low detection limit	1244:1264	a low detection limit	1244:1264	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	6	28	theme	enzymatic	1155:1163	arg1	microchip					1175:1183	an enzymatic biosensor microchip	1152:1183	an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition	1152:1300	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	1	29	theme	applied	188:194	arg1	sources					203:209	the most applied carbon sources	179:209	the most applied carbon sources in the fermentation process	179:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	0	30	theme	Scalable	0:7	arg1	Printing					9:16	Scalable Printing	0:16	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich	0:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	7	31	theme	glucose	1431:1437	arg1	concentrations					1439:1452	the sucrose and glucose concentrations	1415:1452	concentrations	1439:1452	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	4	32	theme	edge-rich	833:841	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	32	theme	edge-rich	833:841	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	1	33	with	metabolism	281:290	arg1	fluctuation					315:325	its concentration fluctuation	297:325	its concentration fluctuation	297:325	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	4	34	theme	sucrose	736:742	arg1	recognition					744:754	accurate sucrose recognition	727:754	accurate sucrose recognition	727:754	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	1	35	theme	carbon	196:201	arg1	sources					203:209	the most applied carbon sources	179:209	the most applied carbon sources in the fermentation process	179:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	0	36	theme	Prussian	21:28	arg1	Edge-Rich					47:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	7	37	theme	fermentation	1334:1345	arg1	reaction					1347:1354	a real alcohol fermentation reaction	1319:1354	a real alcohol fermentation reaction	1319:1354	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	0	38	theme	Fermentation	136:147	arg1	Monitoring					149:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	4	39	theme	blue	816:819	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	39	theme	blue	816:819	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	7	40	with	concentrations	1439:1452	arg1	reusability					1471:1481	outstanding reusability	1459:1481	outstanding reusability (more than 300 times)	1459:1503	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	7	40	with	concentrations	1439:1452	arg1	times					1498:1502	more than 300 times	1484:1502	more than 300 times	1484:1502	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	1	41	theme	sources	203:209	arg1	one					172:174	one	172:174	one	172:174	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	1	41	theme	sources	203:209	arg1	sources					203:209	the most applied carbon sources	179:209	the most applied carbon sources in the fermentation process	179:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	0	42	theme	Sucrose	128:134	arg1	Monitoring					149:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Ultrasensitive Sucrose Fermentation Monitoring	113:158	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	6	43	theme	ultrahigh	1193:1201	arg1	sensitivity					1203:1213	ultrahigh sensitivity	1193:1213	ultrahigh sensitivity	1193:1213	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	3	44	theme	rapid	499:503	arg1	detection					517:525	rapid and precise detection	499:525	rapid and precise detection of sucrose	499:536	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	3	45	from	fermentation	585:596	arg1	desired					548:554	desired	548:554	desired	548:554	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	2	46	theme	biological	412:421	arg1	vaccines					423:430	biological vaccines	412:430	biological vaccines	412:430	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	0	47	theme	Analogue	35:42	arg1	Edge-Rich					47:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	1	48	theme	concentration	301:313	arg1	fluctuation					315:325	its concentration fluctuation	297:325	its concentration fluctuation	297:325	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	4	49	theme	Prussian	807:814	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	49	theme	Prussian	807:814	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	2	50	theme	protective	374:383	arg1	agent					385:389	a protective agent	372:389	a protective agent	372:389	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	0	51	theme	Blue	30:33	arg1	Edge-Rich					47:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	7	52	theme	real	1321:1324	arg1	reaction					1347:1354	a real alcohol fermentation reaction	1319:1354	a real alcohol fermentation reaction	1319:1354	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	1	53	theme	fermentation	218:229	arg1	process					231:237	the fermentation process	214:237	the fermentation process	214:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	2	54	theme	mRNA	455:458	arg1	vaccines					460:467	the new mRNA vaccines	447:467	the new mRNA vaccines for curing COVID-19	447:487	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	0	55	theme	Edge-Rich	47:55	arg1	Printing					9:16	Scalable Printing	0:16	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich	0:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	4	56	theme	analogue	821:828	arg1	microarchitecture					854:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	805:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	4	56	theme	analogue	821:828	arg1	AuER					848:851	PBA@AuER	844:851	PBA@AuER	844:851	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	5	57	dep	regular	1013:1019	arg1	features					1041:1048	features	1041:1048	features	1041:1048	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	5	58	theme	geometric	886:894	arg1	structure					896:904	This special geometric structure	873:904	This special geometric structure	873:904	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	0	59	theme	@	43:43	arg1	Edge-Rich					47:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	4	60	theme	microarchitecture	854:870	arg1	construction					789:800	the construction	785:800	the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture	785:870	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	5	61	theme	continuous	1025:1034	arg1	edge					1036:1039	continuous edge	1025:1039	continuous edge	1025:1039	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	3	62	theme	industrial	574:583	arg1	fermentation					585:596	industrial fermentation	574:596	industrial fermentation	574:596	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	1	63	from	sources	203:209	arg1	process					231:237	the fermentation process	214:237	the fermentation process	214:237	Sucrose is one of the most applied carbon sources in the fermentation process, and it directly determines the microbial metabolism with its concentration fluctuation.					
36048570	4	64	theme	biosensor	697:705	arg1	microchip					707:715	an ultrasensitive biosensor microchip	679:715	an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s	679:771	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	6	65	theme	detection	1223:1231	arg1	range					1233:1237	a wide detection range	1216:1237	a wide detection range	1216:1237	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	6	66	theme	accurate	1273:1280	arg1	recognition					1290:1300	the accurate sucrose recognition	1269:1300	the accurate sucrose recognition	1269:1300	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	7	67	theme	whole	1516:1520	arg1	process					1522:1528	the whole process	1512:1528	the whole process	1512:1528	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	6	68	theme	wide	1218:1221	arg1	range					1233:1237	a wide detection range	1216:1237	a wide detection range	1216:1237	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	4	69	theme	accurate	727:734	arg1	recognition					744:754	accurate sucrose recognition	727:754	accurate sucrose recognition	727:754	In order to address the above issue, we proposed an ultrasensitive biosensor microchip achieving accurate sucrose recognition within only 12 s, relying on the construction of a Prussian blue analogue@Au edge-rich (PBA@AuER) microarchitecture.					
36048570	3	70	from	desired	548:554	arg1	fermentation					585:596	industrial fermentation	574:596	industrial fermentation	574:596	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	3	70	from	desired	548:554	arg1	research					620:627	synthetic biology research	602:627	synthetic biology research	602:627	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	7	71	theme	mixture	1591:1597	arg1	system					1609:1614	the binary mixture substrate system	1580:1614	the binary mixture substrate system	1580:1614	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	5	72	theme	oriented	946:953	arg1	crystallization					959:973	the oriented PBA crystallization	942:973	the oriented PBA crystallization	942:973	This special geometric structure was formed through exactly inducing the oriented PBA crystallization toward a certain plane to create more regular and continuous edge features.					
36048570	7	73	theme	substrate	1599:1607	arg1	system					1609:1614	the binary mixture substrate system	1580:1614	the binary mixture substrate system	1580:1614	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	3	74	theme	synthetic	602:610	arg1	research					620:627	synthetic biology research	602:627	synthetic biology research	602:627	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	2	75	theme	vaccines	423:430	arg1	production					398:407	the production	394:407	the production of biological vaccines	394:430	Meanwhile, sucrose also plays a key role of a protective agent in the production of biological vaccines, especially in the new mRNA vaccines for curing COVID-19.					
36048570	6	76	theme	screen-printed	1095:1108	arg1	ink					1110:1112	a screen-printed ink	1093:1112	a screen-printed ink	1093:1112	This composite was further transformed to a screen-printed ink to directly and large-scale fabricate an enzymatic biosensor microchip showing ultrahigh sensitivity, a wide detection range, and a low detection limit to the accurate sucrose recognition.					
36048570	7	77	theme	alcohol	1326:1332	arg1	reaction					1347:1354	a real alcohol fermentation reaction	1319:1354	a real alcohol fermentation reaction	1319:1354	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36048570	0	78	theme	Au	44:45	arg1	Edge-Rich					47:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Prussian Blue Analogue@Au Edge-Rich	21:55	Scalable Printing of Prussian Blue Analogue@Au Edge-Rich Microcubes as Flexible Biosensing Microchips Performing Ultrasensitive Sucrose Fermentation Monitoring.					
36048570	3	79	theme	biology	612:618	arg1	research					620:627	synthetic biology research	602:627	synthetic biology research	602:627	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	3	80	theme	precise	509:515	arg1	detection					517:525	rapid and precise detection	499:525	rapid and precise detection of sucrose	499:536	However, rapid and precise detection of sucrose is always desired but unrealized in industrial fermentation and synthetic biology research.					
36048570	7	81	theme	binary	1584:1589	arg1	system					1609:1614	the binary mixture substrate system	1580:1614	the binary mixture substrate system	1580:1614	As confirmed in a real alcohol fermentation reaction, the as-prepared microchip enabled us to accurately detect the sucrose and glucose concentrations with outstanding reusability (more than 300 times) during the whole process through proposing a novel analytical strategy for the binary mixture substrate system.					
36535352	0	0	theme	hydrolytic	92:101	arg1	ZnCl2					73:77	acidified ZnCl2	63:77	acidified ZnCl2	63:77	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	0	0	theme	hydrolytic	92:101	arg1	media					103:107	cellulose hydrolytic media	82:107	cellulose hydrolytic media	82:107	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	4	1	theme	ZnCl2	709:713	arg1	solution					715:722	The acidified ZnCl2 solution	695:722	The acidified ZnCl2 solution	695:722	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	1	2	theme	oxide	169:173	arg1	nanoparticles					175:187	zinc oxide nanoparticles	164:187	zinc oxide nanoparticles	164:187	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	0	3	theme	cellulose	82:90	arg1	ZnCl2					73:77	acidified ZnCl2	63:77	acidified ZnCl2	63:77	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	0	3	theme	cellulose	82:90	arg1	media					103:107	cellulose hydrolytic media	82:107	cellulose hydrolytic media	82:107	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	6	4	theme	polyurethane	1109:1120	arg1	films					1128:1132	waterborne polyurethane (WPU) films	1098:1132	waterborne polyurethane (WPU) films	1098:1132	CNC/ZnO nanohybrids were incorporated into waterborne polyurethane (WPU) films.					
36535352	5	5	theme	rod-like	887:894	arg1	nanoparticles					992:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles	872:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure	872:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	6	6	theme	waterborne	1098:1107	arg1	polyurethane					1109:1120	waterborne polyurethane	1098:1120	waterborne polyurethane (WPU) films	1098:1132	CNC/ZnO nanohybrids were incorporated into waterborne polyurethane (WPU) films.					
36535352	6	6	theme	waterborne	1098:1107	arg1	WPU					1123:1125	WPU	1123:1125	WPU	1123:1125	CNC/ZnO nanohybrids were incorporated into waterborne polyurethane (WPU) films.					
36535352	5	7	theme	flower-like	947:957	arg1	nanoparticles					992:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles	872:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure	872:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	8	8	theme	CNC/ZnO	1354:1360	arg1	composites					1362:1371	The 10 % CNC/ZnO composites	1345:1371	The 10 % CNC/ZnO composites	1345:1371	The 10 % CNC/ZnO composites showed inhibition rates to both E. coli and S. aureus above 88.8 %.					
36535352	1	9	theme	bio-based	269:277	arg1	products					279:286	the bio-based products	265:286	the bio-based products	265:286	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	7	10	theme	nanocomposite	1183:1195	arg1	films					1197:1201	the nanocomposite films	1179:1201	the nanocomposite films	1179:1201	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	7	11	dep	29.9 MPa	1264:1271	arg1	to					1261:1262	to	1261:1262	to	1261:1262	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	4	12	theme	hydrolytic	769:778	arg1	media					780:784	cellulose hydrolytic media	759:784	cellulose hydrolytic media	759:784	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	5	13	theme	precursor	840:848	arg1	pH = 9-12					860:868	pH = 9-12	860:868	pH = 9-12	860:868	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	13	theme	precursor	840:848	arg1	solution					850:857	the zinc precursor solution	831:857	the zinc precursor solution (pH = 9-12)	831:869	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	14	with	nanoparticles	992:1004	arg1	structure					1030:1038	hexagonal wurtzite structure	1011:1038	hexagonal wurtzite structure	1011:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	4	15	theme	dual	733:736	arg1	role					738:741	a dual role	731:741	a dual role	731:741	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	7	16	theme	tensile	1159:1165	arg1	strength					1167:1174	tensile strength	1159:1174	tensile strength	1159:1174	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	5	17	theme	zinc	835:838	arg1	pH = 9-12					860:868	pH = 9-12	860:868	pH = 9-12	860:868	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	17	theme	zinc	835:838	arg1	solution					850:857	the zinc precursor solution	831:857	the zinc precursor solution (pH = 9-12)	831:869	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	18	theme	average	960:966	arg1	diameter					968:975	average diameter	960:975	average diameter: 179.6 nm	960:985	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	0	19	theme	ZnO	113:115	arg1	precursor					117:125	ZnO precursor	113:125	ZnO precursor	113:125	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	7	20	theme	CNC/ZnO	1304:1310	arg1	content					1323:1329	CNC/ZnO nanofiller content	1304:1329	CNC/ZnO nanofiller content	1304:1329	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	7	21	theme	films	1197:1201	arg1	modulus					1147:1153	Young's modulus	1139:1153	Young's modulus	1139:1153	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	7	21	theme	films	1197:1201	arg1	strength					1167:1174	tensile strength	1159:1174	tensile strength	1159:1174	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	3	22	theme	subsequent	660:669	arg1	precipitation					680:692	subsequent chemical precipitation	660:692	subsequent chemical precipitation	660:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	2	23	theme	oxide	331:335	arg1	nanohybrids					347:357	cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids	304:357	cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties	304:403	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	7	24	theme	nanofiller	1312:1321	arg1	content					1323:1329	CNC/ZnO nanofiller content	1304:1329	CNC/ZnO nanofiller content	1304:1329	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	0	25	theme	Facile	0:5	arg1	preparation					7:17	Facile preparation	0:17	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.	0:126	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	1	26	with	Hybridization	128:140	arg1	nanoparticles					175:187	zinc oxide nanoparticles	164:187	zinc oxide nanoparticles	164:187	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	2	27	theme	nanocrystal/zinc	314:329	arg1	CNC/ZnO					338:344	CNC/ZnO	338:344	CNC/ZnO	338:344	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	2	27	theme	nanocrystal/zinc	314:329	arg1	oxide					331:335	cellulose nanocrystal/zinc oxide	304:335	cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties	304:403	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	3	28	theme	Microcrystalline	447:462	arg1	cellulose					464:472	Microcrystalline cellulose	447:472	Microcrystalline cellulose (MCC)	447:478	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	3	28	theme	Microcrystalline	447:462	arg1	MCC					475:477	MCC	475:477	MCC	475:477	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	0	29	theme	cellulose	22:30	arg1	hybrids					49:55	cellulose nanocrystals/ZnO hybrids	22:55	cellulose nanocrystals/ZnO hybrids	22:55	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	5	30	theme	wurtzite	1021:1028	arg1	structure					1030:1038	hexagonal wurtzite structure	1011:1038	hexagonal wurtzite structure	1011:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	2	31	theme	cellulose	304:312	arg1	CNC/ZnO					338:344	CNC/ZnO	338:344	CNC/ZnO	338:344	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	2	31	theme	cellulose	304:312	arg1	oxide					331:335	cellulose nanocrystal/zinc oxide	304:335	cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties	304:403	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	3	32	theme	stabilizing	576:586	arg1	agent					603:607	a stabilizing and supporting agent	574:607	a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation	574:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	3	32	theme	stabilizing	576:586	arg1	CNCs					547:550	CNCs	547:550	CNCs	547:550	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	5	33	dep	rod-like	887:894	arg1	length					897:902	length	897:902	length	897:902	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	33	dep	rod-like	887:894	arg1	width					921:925	width	921:925	width	921:925	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	3	34	theme	ZnO	635:637	arg1	nanoparticles					639:651	ZnO nanoparticles	635:651	ZnO nanoparticles during subsequent chemical precipitation	635:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	2	35	theme	one-pot	432:438	arg1	route					440:444	a facile one-pot route	423:444	a facile one-pot route	423:444	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	0	36	theme	hybrids	49:55	arg1	preparation					7:17	Facile preparation	0:17	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.	0:126	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	5	37	dep	diameter	968:975	arg1	179.6 nm					978:985	179.6 nm	978:985	average diameter: 179.6 nm	960:985	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	1	38	theme	zinc	227:230	arg1	oxide					232:236	the zinc oxide	223:236	the zinc oxide	223:236	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	8	39	theme	inhibition	1380:1389	arg1	rates					1391:1395	inhibition rates	1380:1395	inhibition rates	1380:1395	The 10 % CNC/ZnO composites showed inhibition rates to both E. coli and S. aureus above 88.8 %.					
36535352	6	40	theme	CNC/ZnO	1055:1061	arg1	nanohybrids					1063:1073	CNC/ZnO nanohybrids	1055:1073	CNC/ZnO nanohybrids	1055:1073	CNC/ZnO nanohybrids were incorporated into waterborne polyurethane (WPU) films.					
36535352	2	41	theme	facile	425:430	arg1	route					440:444	a facile one-pot route	423:444	a facile one-pot route	423:444	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	0	42	theme	nanocrystals/ZnO	32:47	arg1	hybrids					49:55	cellulose nanocrystals/ZnO hybrids	22:55	cellulose nanocrystals/ZnO hybrids	22:55	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	2	43	with	nanohybrids	347:357	arg1	reinforcing					364:374	reinforcing	364:374	reinforcing	364:374	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	2	43	with	nanohybrids	347:357	arg1	properties					394:403	antibacterial properties	380:403	antibacterial properties	380:403	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	1	44	theme	oxide	232:236	arg1	dispersibility					205:218	the dispersibility	201:218	the dispersibility of the zinc oxide	201:236	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	0	45	theme	acidified	63:71	arg1	ZnCl2					73:77	acidified ZnCl2	63:77	acidified ZnCl2	63:77	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	0	45	theme	acidified	63:71	arg1	media					103:107	cellulose hydrolytic media	82:107	cellulose hydrolytic media	82:107	Facile preparation of cellulose nanocrystals/ZnO hybrids using acidified ZnCl2 as cellulose hydrolytic media and ZnO precursor.					
36535352	5	46	theme	well-dispersed	872:885	arg1	nanoparticles					992:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles	872:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure	872:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	8	47	theme	%	1352:1352	arg1	composites					1362:1371	The 10 % CNC/ZnO composites	1345:1371	The 10 % CNC/ZnO composites	1345:1371	The 10 % CNC/ZnO composites showed inhibition rates to both E. coli and S. aureus above 88.8 %.					
36535352	3	48	theme	nanoparticles	639:651	arg1	growth					625:630	the in-situ growth	613:630	the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation	613:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	5	49	theme	hexagonal	1011:1019	arg1	structure					1030:1038	hexagonal wurtzite structure	1011:1038	hexagonal wurtzite structure	1011:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	50	dep	length	897:902	arg1	137.0-468.0 nm					905:918	137.0-468.0 nm	905:918	137.0-468.0 nm	905:918	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	5	50	dep	length	897:902	arg1	54.1-154.1 nm					928:940	54.1-154.1 nm	928:940	54.1-154.1 nm	928:940	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	3	51	theme	acidified	503:511	arg1	chloride					518:525	acidified zinc chloride	503:525	acidified zinc chloride	503:525	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	7	52	theme	Young	1139:1143	arg1	modulus					1147:1153	Young's modulus	1139:1153	Young's modulus	1139:1153	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	3	53	theme	supporting	592:601	arg1	agent					603:607	a stabilizing and supporting agent	574:607	a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation	574:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	3	53	theme	supporting	592:601	arg1	CNCs					547:550	CNCs	547:550	CNCs	547:550	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	3	54	theme	zinc	513:516	arg1	chloride					518:525	acidified zinc chloride	503:525	acidified zinc chloride	503:525	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	5	55	theme	ZnO	988:990	arg1	nanoparticles					992:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles	872:1004	well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure	872:1038	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	8	56	theme	10 	1349:1351	arg1	%					1352:1352	%	1352:1352	%	1352:1352	The 10 % CNC/ZnO composites showed inhibition rates to both E. coli and S. aureus above 88.8 %.					
36535352	4	57	theme	acidified	699:707	arg1	solution					715:722	The acidified ZnCl2 solution	695:722	The acidified ZnCl2 solution	695:722	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	5	58	dep	flower-like	947:957	arg1	diameter					968:975	average diameter	960:975	average diameter: 179.6 nm	960:985	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	4	59	theme	cellulose	759:767	arg1	media					780:784	cellulose hydrolytic media	759:784	cellulose hydrolytic media	759:784	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	3	60	theme	chemical	671:678	arg1	precipitation					680:692	subsequent chemical precipitation	660:692	subsequent chemical precipitation	660:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	4	61	theme	ZnO	793:795	arg1	precursor					797:805	ZnO precursor	793:805	ZnO precursor	793:805	The acidified ZnCl2 solution played a dual role, acting both as cellulose hydrolytic media and as ZnO precursor.					
36535352	1	62	theme	nanocellulose	145:157	arg1	Hybridization					128:140	Hybridization	128:140	Hybridization of nanocellulose with zinc oxide nanoparticles	128:187	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	5	63	theme	solution	850:857	arg1	pH					825:826	the pH	821:826	the pH of the zinc precursor solution (pH = 9-12)	821:869	By adjusting the pH of the zinc precursor solution (pH = 9-12), well-dispersed rod-like (length: 137.0-468.0 nm, width: 54.1-154.1 nm) and flower-like (average diameter: 179.6 nm) ZnO nanoparticles with hexagonal wurtzite structure were obtained.					
36535352	7	64	theme	10 wt	1337:1341	arg1	%					1342:1342	10 wt%	1337:1342	10 wt%	1337:1342	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
36535352	2	65	theme	antibacterial	380:392	arg1	properties					394:403	antibacterial properties	380:403	antibacterial properties	380:403	In this study, cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids with reinforcing and antibacterial properties were prepared via a facile one-pot route.					
36535352	1	66	theme	new	248:250	arg1	functions					252:260	new functions	248:260	new functions	248:260	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	3	67	theme	in-situ	617:623	arg1	growth					625:630	the in-situ growth	613:630	the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation	613:692	Microcrystalline cellulose (MCC) was first treated with acidified zinc chloride and hydrolyzed into CNCs, which then served as a stabilizing and supporting agent for the in-situ growth of ZnO nanoparticles during subsequent chemical precipitation.					
36535352	1	68	theme	zinc	164:167	arg1	nanoparticles					175:187	zinc oxide nanoparticles	164:187	zinc oxide nanoparticles	164:187	Hybridization of nanocellulose with zinc oxide nanoparticles can improve the dispersibility of the zinc oxide and bring new functions to the bio-based products.					
36535352	7	69	dep	modulus	1147:1153	arg1	The					1135:1137	The	1135:1137	The	1135:1137	The Young's modulus and tensile strength of the nanocomposite films increased gradually from 154.8 to 509.0 MPa and from 16.5 to 29.9 MPa, respectively, with increasing CNC/ZnO nanofiller content up to 10 wt%.					
37392452	8	0	theme	chromatography	1198:1211	arg1	analysis					1213:1220	high-performance liquid chromatography analysis	1174:1220	high-performance liquid chromatography analysis	1174:1220	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	1	1	theme	food	187:190	arg1	samples					192:198	food samples	187:198	food samples	187:198	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	8	2	from	potential	1302:1310	arg1	separation					1319:1328	the separation	1315:1328	the separation of neomycin from complicated aquatic products	1315:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	8	2	from	potential	1302:1310	arg1	products					1367:1374	complicated aquatic products	1347:1374	complicated aquatic products	1347:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	4	3	theme	emulsification	591:604	arg1	strategies					606:615	emulsification strategies	591:615	emulsification strategies	591:615	A versatile macroporous agarose monolith was prepared by emulsification strategies and functionalized with epoxy groups.					
37392452	8	4	theme	liquid	1191:1196	arg1	chromatography					1198:1211	high-performance liquid chromatography	1174:1211	high-performance liquid chromatography analysis	1174:1220	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	8	5	theme	spiked	1132:1137	arg1	products					1153:1160	the spiked model aquatic products	1128:1160	the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products	1128:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	5	6	theme	polyethyleneimine-integrated	673:700	arg1	nanoparticles					709:721	polyethyleneimine-integrated silica nanoparticles	673:721	polyethyleneimine-integrated silica nanoparticles	673:721	After introducing polyethyleneimine-integrated silica nanoparticles onto the agarose monolith, fluorophenylboronic acids were immobilized.					
37392452	8	7	theme	aquatic	1145:1151	arg1	products					1153:1160	the spiked model aquatic products	1128:1160	the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products	1128:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	8	8	theme	neomycin	1333:1340	arg1	separation					1319:1328	the separation	1315:1328	the separation of neomycin from complicated aquatic products	1315:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	4	9	theme	macroporous	546:556	arg1	monolith					566:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith was prepared by emulsification strategies and functionalized with epoxy groups.					
37392452	5	10	theme	agarose	732:738	arg1	monolith					740:747	the agarose monolith	728:747	the agarose monolith	728:747	After introducing polyethyleneimine-integrated silica nanoparticles onto the agarose monolith, fluorophenylboronic acids were immobilized.					
37392452	8	11	theme	composite	1059:1067	arg1	monolith					1069:1076	The composite monolith	1055:1076	The composite monolith	1055:1076	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	0	12	theme	Neomycin	138:145	arg1	Separation					124:133	the Separation	120:133	the Separation of Neomycin	120:145	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	4	13	theme	versatile	536:544	arg1	monolith					566:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith was prepared by emulsification strategies and functionalized with epoxy groups.					
37392452	8	14	theme	model	1139:1143	arg1	products					1153:1160	the spiked model aquatic products	1128:1160	the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products	1128:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	3	15	with	modification	464:475	arg1	polyethyleneimine					515:531	polyethyleneimine	515:531	polyethyleneimine	515:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	15	with	modification	464:475	arg1	incorporation					498:510	incorporation	498:510	incorporation of polyethyleneimine	498:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	15	with	modification	464:475	arg1	group					488:492	amino group	482:492	amino group	482:492	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	16	theme	amino	482:486	arg1	polyethyleneimine					515:531	polyethyleneimine	515:531	polyethyleneimine	515:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	16	theme	amino	482:486	arg1	group					488:492	amino group	482:492	amino group	482:492	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	8	17	theme	complicated	1347:1357	arg1	products					1367:1374	complicated aquatic products	1347:1374	complicated aquatic products	1347:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	5	18	theme	fluorophenylboronic	750:768	arg1	acids					770:774	fluorophenylboronic acids	750:774	fluorophenylboronic acids	750:774	After introducing polyethyleneimine-integrated silica nanoparticles onto the agarose monolith, fluorophenylboronic acids were immobilized.					
37392452	6	19	theme	composite	843:851	arg1	monolith					853:860	the composite monolith	839:860	the composite monolith	839:860	The physical and chemical characteristics of the composite monolith were analyzed systematically.					
37392452	8	20	theme	aquatic	1359:1365	arg1	products					1367:1374	complicated aquatic products	1347:1374	complicated aquatic products	1347:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	0	21	theme	Macroporous	13:23	arg1	Materials					33:41	Hierarchical Macroporous Agarose Materials	0:41	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.	0:146	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	4	22	theme	agarose	558:564	arg1	monolith					566:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith	534:573	A versatile macroporous agarose monolith was prepared by emulsification strategies and functionalized with epoxy groups.					
37392452	8	23	theme	high-performance	1174:1189	arg1	chromatography					1198:1211	high-performance liquid chromatography	1174:1211	high-performance liquid chromatography analysis	1174:1220	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	3	24	theme	silica	392:397	arg1	core					399:402	The silica core	388:402	The silica core	388:402	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	2	25	theme	neomycin	378:385	arg1	separation					364:373	selective separation	354:373	selective separation of neomycin	354:385	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	1	26	theme	efficient	211:219	arg1	platform					234:241	an efficient purification platform	208:241	an efficient purification platform	208:241	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	0	27	theme	Hierarchical	0:11	arg1	Materials					33:41	Hierarchical Macroporous Agarose Materials	0:41	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.	0:146	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	5	28	theme	silica	702:707	arg1	nanoparticles					709:721	polyethyleneimine-integrated silica nanoparticles	673:721	polyethyleneimine-integrated silica nanoparticles	673:721	After introducing polyethyleneimine-integrated silica nanoparticles onto the agarose monolith, fluorophenylboronic acids were immobilized.					
37392452	1	29	theme	purification	221:232	arg1	platform					234:241	an efficient purification platform	208:241	an efficient purification platform	208:241	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	3	30	theme	one-step	424:431	arg1	procedures					441:450	"one-step" Stöber procedures	423:450	"one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine	423:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	4	31	theme	epoxy	641:645	arg1	groups					647:652	epoxy groups	641:652	epoxy groups	641:652	A versatile macroporous agarose monolith was prepared by emulsification strategies and functionalized with epoxy groups.					
37392452	8	32	theme	purification	1260:1271	arg1	effect					1273:1278	a remarkable neomycin purification effect	1238:1278	a remarkable neomycin purification effect	1238:1278	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	1	33	from	Quantification	148:161	arg1	samples					192:198	food samples	187:198	food samples	187:198	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	0	34	theme	Agarose	25:31	arg1	Materials					33:41	Hierarchical Macroporous Agarose Materials	0:41	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.	0:146	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	2	35	with	monoliths	285:293	arg1	sites					327:331	multiple boronate affinity sites	300:331	multiple boronate affinity sites	300:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	8	36	theme	neomycin	1251:1258	arg1	effect					1273:1278	a remarkable neomycin purification effect	1238:1278	a remarkable neomycin purification effect	1238:1278	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	2	37	theme	selective	354:362	arg1	separation					364:373	selective separation	354:373	selective separation of neomycin	354:385	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	6	38	theme	chemical	811:818	arg1	characteristics					820:834	The physical and chemical characteristics	794:834	The physical and chemical characteristics of the composite monolith	794:860	The physical and chemical characteristics of the composite monolith were analyzed systematically.					
37392452	0	39	theme	Polyethyleneimine-Assisted	48:73	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	6	40	theme	monolith	853:860	arg1	characteristics					820:834	The physical and chemical characteristics	794:834	The physical and chemical characteristics of the composite monolith	794:860	The physical and chemical characteristics of the composite monolith were analyzed systematically.					
37392452	7	41	theme	binding	972:978	arg1	capacity					980:987	the binding capacity	968:987	the binding capacity	968:987	After optimization, neomycin showed high binding ability of 23.69 mg/g, and the binding capacity can be manipulated by changing the pH and adding monosaccharides.					
37392452	8	42	theme	remarkable	1240:1249	arg1	effect					1273:1278	a remarkable neomycin purification effect	1238:1278	a remarkable neomycin purification effect	1238:1278	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	2	43	theme	agarose	277:283	arg1	monoliths					285:293	hierarchical macroporous agarose monoliths	252:293	hierarchical macroporous agarose monoliths with multiple boronate affinity sites	252:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	0	44	with	Materials	33:41	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	3	45	theme	polyethyleneimine	515:531	arg1	polyethyleneimine					515:531	polyethyleneimine	515:531	polyethyleneimine	515:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	45	theme	polyethyleneimine	515:531	arg1	incorporation					498:510	incorporation	498:510	incorporation of polyethyleneimine	498:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	45	theme	polyethyleneimine	515:531	arg1	group					488:492	amino group	482:492	amino group	482:492	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	0	46	theme	Boronate	84:91	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	7	47	theme	mg/g	958:961	arg1	ability					941:947	high binding ability	928:947	high binding ability of 23.69 mg/g	928:961	After optimization, neomycin showed high binding ability of 23.69 mg/g, and the binding capacity can be manipulated by changing the pH and adding monosaccharides.					
37392452	2	48	theme	macroporous	265:275	arg1	monoliths					285:293	hierarchical macroporous agarose monoliths	252:293	hierarchical macroporous agarose monoliths with multiple boronate affinity sites	252:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	0	49	theme	Multiple	75:82	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	7	50	theme	high	928:931	arg1	ability					941:947	high binding ability	928:947	high binding ability of 23.69 mg/g	928:961	After optimization, neomycin showed high binding ability of 23.69 mg/g, and the binding capacity can be manipulated by changing the pH and adding monosaccharides.					
37392452	2	51	theme	hierarchical	252:263	arg1	monoliths					285:293	hierarchical macroporous agarose monoliths	252:293	hierarchical macroporous agarose monoliths with multiple boronate affinity sites	252:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	6	52	theme	physical	798:805	arg1	characteristics					820:834	The physical and chemical characteristics	794:834	The physical and chemical characteristics of the composite monolith	794:860	The physical and chemical characteristics of the composite monolith were analyzed systematically.					
37392452	7	53	theme	binding	933:939	arg1	ability					941:947	high binding ability	928:947	high binding ability of 23.69 mg/g	928:961	After optimization, neomycin showed high binding ability of 23.69 mg/g, and the binding capacity can be manipulated by changing the pH and adding monosaccharides.					
37392452	2	54	theme	affinity	318:325	arg1	sites					327:331	multiple boronate affinity sites	300:331	multiple boronate affinity sites	300:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	8	55	used	utilized	1095:1102	arg2	monolith					1069:1076	The composite monolith	1055:1076	The composite monolith	1055:1076	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	8	56	theme	great	1296:1300	arg1	potential					1302:1310	the great potential	1292:1310	the great potential in the separation of neomycin from complicated aquatic products	1292:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	2	57	theme	boronate	309:316	arg1	sites					327:331	multiple boronate affinity sites	300:331	multiple boronate affinity sites	300:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	1	58	theme	neomycin	166:173	arg1	residues					175:182	neomycin residues	166:182	neomycin residues	166:182	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	0	59	theme	Binding	102:108	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	2	60	theme	multiple	300:307	arg1	sites					327:331	multiple boronate affinity sites	300:331	multiple boronate affinity sites	300:331	Herein, hierarchical macroporous agarose monoliths with multiple boronate affinity sites were established for selective separation of neomycin.					
37392452	1	61	theme	residues	175:182	arg1	Quantification					148:161	Quantification	148:161	Quantification of neomycin residues in food samples	148:198	Quantification of neomycin residues in food samples demands an efficient purification platform.					
37392452	8	62	from	products	1367:1374	arg1	separation					1319:1328	the separation	1315:1328	the separation of neomycin from complicated aquatic products	1315:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	8	62	from	products	1367:1374	arg1	potential					1302:1310	the great potential	1292:1310	the great potential in the separation of neomycin from complicated aquatic products	1292:1374	The composite monolith was subsequently utilized to purify neomycin from the spiked model aquatic products followed by high-performance liquid chromatography analysis, which revealed a remarkable neomycin purification effect, indicating the great potential in the separation of neomycin from complicated aquatic products.					
37392452	0	63	theme	Affinity	93:100	arg1	Sites					110:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites	48:114	Hierarchical Macroporous Agarose Materials with Polyethyleneimine-Assisted Multiple Boronate Affinity Binding Sites for the Separation of Neomycin.					
37392452	3	64	theme	"	432:432	arg1	procedures					441:450	"one-step" Stöber procedures	423:450	"one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine	423:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
37392452	3	65	theme	Stöber	434:439	arg1	procedures					441:450	"one-step" Stöber procedures	423:450	"one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine	423:531	The silica core was synthesized by "one-step" Stöber procedures followed by modification with amino group and incorporation of polyethyleneimine.					
36282126	5	0	theme	transmission	897:908	arg1	microscopy					919:928	transmission electron microscopy	897:928	transmission electron microscopy	897:928	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	5	1	theme	electron	910:917	arg1	microscopy					919:928	transmission electron microscopy	897:928	transmission electron microscopy	897:928	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	3	2	dep	calorimetry	485:495	arg1	results					497:503	results	497:503	The isothermal titration calorimetry results	460:503	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	6	3	theme	proteins	1216:1223	arg1	stabilization					1199:1211	stabilization	1199:1211	stabilization of proteins	1199:1223	In brief, it provided a synthesis strategy for the precise preparation of trehalose-glycopolypeptides, as well as a suitable method for stabilization of proteins.					
36282126	4	4	dep	activity	716:723	arg1	%					704:704	%	704:704	%	704:704	These PICs allowed GOx to maintain an approximately 80% enzymatic activity compared with native GOx after 6× lyophilization.					
36282126	4	5	theme	native	739:744	arg1	GOx					746:748	native GOx	739:748	native GOx after 6× lyophilization	739:772	These PICs allowed GOx to maintain an approximately 80% enzymatic activity compared with native GOx after 6× lyophilization.					
36282126	1	6	theme	proteins	100:107	arg1	Protection					86:95	Protection	86:95	Protection of proteins	86:107	Protection of proteins is of great significance since external stimuli can cause denaturation due to aggregation.					
36282126	4	7	dep	%	704:704	arg1	80					702:703	80	702:703	80	702:703	These PICs allowed GOx to maintain an approximately 80% enzymatic activity compared with native GOx after 6× lyophilization.					
36282126	6	8	theme	precise	1114:1120	arg1	preparation					1122:1132	the precise preparation	1110:1132	the precise preparation of trehalose-glycopolypeptides	1110:1163	In brief, it provided a synthesis strategy for the precise preparation of trehalose-glycopolypeptides, as well as a suitable method for stabilization of proteins.					
36282126	2	9	theme	protein	392:398	arg1	stabilization					367:379	stabilization	367:379	stabilization of a model protein, glucose oxidase (GOx),	367:422	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	5	10	theme	positive	822:829	arg1	effect					831:836	a positive effect	820:836	a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx	820:1060	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	5	11	from	effect	831:836	arg1	protection					845:854	the protection	841:854	the protection of GOx	841:861	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	2	12	theme	model	386:390	arg1	protein					392:398	a model protein	384:398	a model protein	384:398	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	12	theme	model	386:390	arg1	oxidase					409:415	glucose oxidase	401:415	glucose oxidase (GOx)	401:421	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	1	13	theme	great	115:119	arg1	significance					121:132	great significance	115:132	great significance	115:132	Protection of proteins is of great significance since external stimuli can cause denaturation due to aggregation.					
36282126	6	14	theme	synthesis	1087:1095	arg1	strategy					1097:1104	a synthesis strategy	1085:1104	a synthesis strategy for the precise preparation of trehalose-glycopolypeptides	1085:1163	In brief, it provided a synthesis strategy for the precise preparation of trehalose-glycopolypeptides, as well as a suitable method for stabilization of proteins.					
36282126	6	15	theme	suitable	1179:1186	arg1	method					1188:1193	a suitable method	1177:1193	a suitable method for stabilization of proteins	1177:1223	In brief, it provided a synthesis strategy for the precise preparation of trehalose-glycopolypeptides, as well as a suitable method for stabilization of proteins.					
36282126	4	16	theme	6×	756:757	arg1	lyophilization					759:772	6× lyophilization	756:772	6× lyophilization	756:772	These PICs allowed GOx to maintain an approximately 80% enzymatic activity compared with native GOx after 6× lyophilization.					
36282126	2	17	theme	l-methionine-g-trehalose	296:319	arg1	PEG45-b-					324:331	PEG45-b-	324:331	PEG45-b-	324:331	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	17	theme	l-methionine-g-trehalose	296:319	arg1	trehalose-glycopolypeptides					242:268	well-defined cationic trehalose-glycopolypeptides	220:268	well-defined cationic trehalose-glycopolypeptides	220:268	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	17	theme	l-methionine-g-trehalose	296:319	arg1	s					321:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s	271:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	5	18	theme	protein	991:997	arg1	aggregation					999:1009	protein aggregation	991:1009	protein aggregation	991:1009	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	4	19	theme	enzymatic	706:714	arg1	activity					716:723	an approximately 80% enzymatic activity	685:723	an approximately 80% enzymatic activity	685:723	These PICs allowed GOx to maintain an approximately 80% enzymatic activity compared with native GOx after 6× lyophilization.					
36282126	0	20	theme	Protein	63:69	arg1	Stabilization					71:83	Protein Stabilization	63:83	Protein Stabilization	63:83	Sulfonium-Containing Glycopolypeptides Tethering Trehalose for Protein Stabilization.					
36282126	5	21	theme	GOx	1058:1060	arg1	function					1046:1053	the bioactive function	1032:1053	the bioactive function of GOx	1032:1060	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	5	22	theme	GOx	859:861	arg1	protection					845:854	the protection	841:854	the protection of GOx	841:861	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	0	23	theme	Tethering	39:47	arg1	Trehalose					49:57	Tethering Trehalose	39:57	Tethering Trehalose	39:57	Sulfonium-Containing Glycopolypeptides Tethering Trehalose for Protein Stabilization.					
36282126	2	24	theme	poly	271:274	arg1	PEG45-b-					324:331	PEG45-b-	324:331	PEG45-b-	324:331	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	24	theme	poly	271:274	arg1	trehalose-glycopolypeptides					242:268	well-defined cationic trehalose-glycopolypeptides	220:268	well-defined cationic trehalose-glycopolypeptides	220:268	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	24	theme	poly	271:274	arg1	s					321:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s	271:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	25	theme	glucose	401:407	arg1	protein					392:398	a model protein	384:398	a model protein	384:398	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	25	theme	glucose	401:407	arg1	oxidase					409:415	glucose oxidase	401:415	glucose oxidase (GOx)	401:421	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	25	theme	glucose	401:407	arg1	GOx					418:420	GOx	418:420	GOx	418:420	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	5	26	dep	heating	868:874	arg1	suggested					930:938	suggested	930:938	suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx	930:1060	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	6	27	theme	trehalose-glycopolypeptides	1137:1163	arg1	preparation					1122:1132	the precise preparation	1110:1132	the precise preparation of trehalose-glycopolypeptides	1110:1163	In brief, it provided a synthesis strategy for the precise preparation of trehalose-glycopolypeptides, as well as a suitable method for stabilization of proteins.					
36282126	1	28	theme	external	140:147	arg1	stimuli					149:155	external stimuli	140:155	external stimuli	140:155	Protection of proteins is of great significance since external stimuli can cause denaturation due to aggregation.					
36282126	2	29	theme	cationic	233:240	arg1	trehalose-glycopolypeptides					242:268	well-defined cationic trehalose-glycopolypeptides	220:268	well-defined cationic trehalose-glycopolypeptides	220:268	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	29	theme	cationic	233:240	arg1	s					321:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s	271:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	30	theme	trehalose-glycopolypeptides	242:268	arg1	series					210:215	a series	208:215	a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)),	208:344	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	31	theme	well-defined	220:231	arg1	trehalose-glycopolypeptides					242:268	well-defined cationic trehalose-glycopolypeptides	220:268	well-defined cationic trehalose-glycopolypeptides	220:268	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	31	theme	well-defined	220:231	arg1	s					321:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s	271:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	32	theme	-b-	292:294	arg1	PEG45-b-					324:331	PEG45-b-	324:331	PEG45-b-	324:331	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	32	theme	-b-	292:294	arg1	trehalose-glycopolypeptides					242:268	well-defined cationic trehalose-glycopolypeptides	220:268	well-defined cationic trehalose-glycopolypeptides	220:268	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	32	theme	-b-	292:294	arg1	s					321:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s	271:321	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	3	33	theme	isothermal	464:473	arg1	calorimetry					485:495	The isothermal titration calorimetry results	460:503	The isothermal titration calorimetry results	460:503	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	5	34	theme	microscopy	919:928	arg1	Results					886:892	Results	886:892	Results of transmission electron microscopy	886:928	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	5	35	theme	bioactive	1036:1044	arg1	function					1046:1053	the bioactive function	1032:1053	the bioactive function of GOx	1032:1060	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	3	36	theme	titration	475:483	arg1	calorimetry					485:495	The isothermal titration calorimetry results	460:503	The isothermal titration calorimetry results	460:503	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	3	37	theme	electrostatic	622:634	arg1	interactions					636:647	electrostatic interactions	622:647	electrostatic interactions	622:647	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	5	38	from	°C.	882:884	arg1	heating					868:874	heating	868:874	heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx	868:1060	Meanwhile, PEG45-b-(Met-g-Tre) also provided a positive effect on the protection of GOx upon heating at 60 °C. Results of transmission electron microscopy suggested that the trehalose-glycopolypeptides could prevent protein aggregation, thereby maintaining the bioactive function of GOx.					
36282126	3	39	theme	polyionic	519:527	arg1	PICs					540:543	PICs	540:543	PICs	540:543	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	3	39	theme	polyionic	519:527	arg1	complexes					529:537	polyionic complexes	519:537	polyionic complexes (PICs)	519:544	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
36282126	2	40	theme	ethylene	276:283	arg1	poly					271:274	poly	271:274	poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre))	271:343	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	2	40	theme	ethylene	276:283	arg1	glycol					285:290	ethylene glycol	276:290	ethylene glycol	276:290	Herein, a series of well-defined cationic trehalose-glycopolypeptides, poly(ethylene glycol)-b-(l-methionine-g-trehalose)s (PEG45-b-(Met-g-Tre)), were synthesized for stabilization of a model protein, glucose oxidase (GOx), against lyophilization and heating.					
36282126	3	41	theme	synthesized	570:580	arg1	trehalose-glycopolypeptides					582:608	the synthesized trehalose-glycopolypeptides	566:608	the synthesized trehalose-glycopolypeptides	566:608	The isothermal titration calorimetry results revealed that polyionic complexes (PICs) were formed between the synthesized trehalose-glycopolypeptides and GOx via electrostatic interactions.					
35352182	2	0	theme	clogging	613:620	arg1	problem					622:628	the clogging problem	609:628	the clogging problem of packed adsorbent	609:648	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	7	1	theme	L-1	1366:1368	arg1	pyrene					1382:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	7	2	theme	0.020-50 µg	1221:1231	arg1	L-1					1233:1235	0.020-50 µg L-1	1221:1235	0.020-50 µg L-1	1221:1235	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	1	3	theme	Cellulose	213:221	arg1	fibers					231:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	7	4	dep	anthracene	1337:1346	arg1	a					1335:1335	a	1335:1335	a	1335:1335	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	0	5	theme	metal-organic	96:108	arg1	framework					110:118	an iron-carboxylate metal-organic framework	76:118	an iron-carboxylate metal-organic framework	76:118	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	6	6	theme	liquid	1088:1093	arg1	chromatography					1095:1108	High-performance liquid chromatography	1071:1108	High-performance liquid chromatography	1071:1108	High-performance liquid chromatography was employed to separate and quantify extracted PAHs.					
35352182	1	7	link	hypercrosslinked	347:362	arg1	composite					372:380	hypercrosslinked polymer composite	347:380	hypercrosslinked polymer composite	347:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	1	8	theme	acetate	223:229	arg1	fibers					231:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	0	9	theme	hypercrosslinked	124:139	arg1	gelatin					159:165	hypercrosslinked polymer composite gelatin	124:165	hypercrosslinked polymer composite gelatin	124:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	6	10	theme	High-performance	1071:1086	arg1	chromatography					1095:1108	High-performance liquid chromatography	1071:1108	High-performance liquid chromatography	1071:1108	High-performance liquid chromatography was employed to separate and quantify extracted PAHs.					
35352182	2	11	theme	aromatic	468:475	arg1	hydrocarbons					477:488	polycyclic aromatic hydrocarbons	457:488	polycyclic aromatic hydrocarbons	457:488	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	2	12	theme	hybrid	387:392	arg1	materials					405:413	The hybrid adsorption materials	383:413	The hybrid adsorption materials	383:413	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	4	13	theme	polycyclic	876:885	arg1	hydrocarbons					896:907	extract and preconcentrate polycyclic aromatic hydrocarbons	849:907	extract and preconcentrate polycyclic aromatic hydrocarbons in water sample	849:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	1	14	theme	hypercrosslinked	347:362	arg1	composite					372:380	hypercrosslinked polymer composite	347:380	hypercrosslinked polymer composite	347:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	4	15	theme	preconcentrate	861:874	arg1	hydrocarbons					896:907	extract and preconcentrate polycyclic aromatic hydrocarbons	849:907	extract and preconcentrate polycyclic aromatic hydrocarbons in water sample	849:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	4	16	theme	syringe	829:835	arg1	hub					809:811	the needle hub	798:811	the needle hub of a disposable syringe	798:835	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	1	17	theme	polymer	364:370	arg1	composite					372:380	hypercrosslinked polymer composite	347:380	hypercrosslinked polymer composite	347:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	0	18	theme	composite	149:157	arg1	gelatin					159:165	hypercrosslinked polymer composite gelatin	124:165	hypercrosslinked polymer composite gelatin	124:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	7	19	theme	a	1401:1401	arg1	anthracene					1405:1414	dibenzo(a,h)anthracene	1393:1414	anthracene	1405:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	5	20	theme	extraction	990:999	arg1	conditions					1001:1010	extraction conditions	990:1010	extraction conditions	990:1010	The fabricated porous composite adsorbent was characterized and extraction conditions were optimized to achieve the best extraction performance.					
35352182	4	21	used	used	841:844	arg2	adsorbent					772:780	adsorbent	772:780	adsorbent	772:780	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	8	22	theme	detection	1431:1439	arg1	limits					1421:1426	The limits	1417:1426	The limits of detection	1417:1439	The limits of detection ranged from 0.5 to 5.0 ng L-1.					
35352182	0	23	theme	polymer	141:147	arg1	gelatin					159:165	hypercrosslinked polymer composite gelatin	124:165	hypercrosslinked polymer composite gelatin	124:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	2	24	theme	acetate	571:577	arg1	fibers					579:584	cellulose acetate fibers	561:584	cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent	561:648	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	10	25	theme	desorption	1613:1622	arg1	cycles					1578:1583	up to 21 cycles	1569:1583	up to 21 cycles of efficient extraction and desorption	1569:1622	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	2	26	theme	gelatin	514:520	arg1	cryogel					522:528	gelatin cryogel	514:528	gelatin cryogel	514:528	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	0	27	theme	solid-phase	11:21	arg1	extraction					23:32	In-syringe solid-phase extraction	0:32	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin	0:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	7	28	theme	for	1370:1372	arg1	pyrene					1382:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	10	29	theme	good	1529:1532	arg1	stability					1534:1542	The good stability	1525:1542	The good stability of the adsorbent	1525:1559	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	7	30	theme	benzo	1374:1378	arg1	pyrene					1382:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	3	31	theme	solid	695:699	arg1	adsorbent					665:673	adsorbent	665:673	adsorbent	665:673	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	3	31	theme	solid	695:699	arg1	phase					701:705	the solid phase	691:705	the solid phase of an in-syringe miniaturized solid-phase extraction system	691:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	0	32	theme	In-syringe	0:9	arg1	extraction					23:32	In-syringe solid-phase extraction	0:32	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin	0:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	8	33	theme	5.0 ng	1460:1465	arg1	L-1					1467:1469	5.0 ng L-1	1460:1469	5.0 ng L-1	1460:1469	The limits of detection ranged from 0.5 to 5.0 ng L-1.					
35352182	4	34	theme	needle	802:807	arg1	hub					809:811	the needle hub	798:811	the needle hub of a disposable syringe	798:835	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	2	35	theme	cellulose	561:569	arg1	fibers					579:584	cellulose acetate fibers	561:584	cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent	561:648	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	7	36	dep	anthracene	1405:1414	arg1	h					1403:1403	dibenzo(a,h)anthracene	1393:1414	h	1403:1403	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	7	37	theme	benzo	1258:1262	arg1	fluoranthene					1266:1277	benzo(b)fluoranthene	1258:1277	benzo(b)fluoranthene	1258:1277	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	4	38	from	hydrocarbons	896:907	arg1	sample					918:923	water sample	912:923	water sample	912:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	4	39	theme	aromatic	887:894	arg1	hydrocarbons					896:907	extract and preconcentrate polycyclic aromatic hydrocarbons	849:907	extract and preconcentrate polycyclic aromatic hydrocarbons in water sample	849:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	10	40	dep	21	1575:1576	arg1	to					1572:1573	to	1572:1573	to	1572:1573	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	6	41	theme	extracted	1148:1156	arg1	PAHs					1158:1161	extracted PAHs	1148:1161	extracted PAHs	1148:1161	High-performance liquid chromatography was employed to separate and quantify extracted PAHs.					
35352182	7	42	theme	0.010-50 µg	1280:1290	arg1	L-1					1292:1294	0.010-50 µg L-1	1280:1294	0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene	1280:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	7	42	theme	0.010-50 µg	1280:1290	arg1	phenanthrene					1241:1252	phenanthrene	1241:1252	phenanthrene	1241:1252	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	2	43	theme	adsorption	394:403	arg1	materials					405:413	The hybrid adsorption materials	383:413	The hybrid adsorption materials	383:413	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	1	44	theme	gelatin	259:265	arg1	cryogel					267:273	a gelatin cryogel adsorbent	257:283	a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite	257:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	0	45	theme	aromatic	48:55	arg1	hydrocarbons					57:68	polycyclic aromatic hydrocarbons	37:68	polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin	37:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	10	46	theme	adsorbent	1551:1559	arg1	stability					1534:1542	The good stability	1525:1542	The good stability of the adsorbent	1525:1559	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	3	47	theme	in-syringe	713:722	arg1	system					760:765	an in-syringe miniaturized solid-phase extraction system	710:765	an in-syringe miniaturized solid-phase extraction system	710:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	0	48	theme	polycyclic	37:46	arg1	hydrocarbons					57:68	polycyclic aromatic hydrocarbons	37:68	polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin	37:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	10	49	theme	efficient	1588:1596	arg1	extraction					1598:1607	efficient extraction	1588:1607	efficient extraction	1588:1607	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	3	50	theme	miniaturized	724:735	arg1	system					760:765	an in-syringe miniaturized solid-phase extraction system	710:765	an in-syringe miniaturized solid-phase extraction system	710:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	7	51	theme	linear	1205:1210	arg1	range					1212:1216	a linear range	1203:1216	a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene	1203:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	1	52	theme	adsorbent	275:283	arg1	cryogel					267:273	a gelatin cryogel adsorbent	257:283	a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite	257:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	2	53	theme	adsorbent	640:648	arg1	problem					622:628	the clogging problem	609:628	the clogging problem of packed adsorbent	609:648	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	7	54	theme	L-1	1233:1235	arg1	range					1212:1216	a linear range	1203:1216	a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene	1203:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	2	55	theme	polycyclic	457:466	arg1	hydrocarbons					477:488	polycyclic aromatic hydrocarbons	457:488	polycyclic aromatic hydrocarbons	457:488	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	0	56	theme	hydrocarbons	57:68	arg1	extraction					23:32	In-syringe solid-phase extraction	0:32	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin	0:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	7	57	theme	developed	1168:1176	arg1	method					1187:1192	The developed analysis method	1164:1192	The developed analysis method	1164:1192	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	10	58	theme	extraction	1598:1607	arg1	cycles					1578:1583	up to 21 cycles	1569:1583	up to 21 cycles of efficient extraction and desorption	1569:1622	The good stability of the adsorbent allowed up to 21 cycles of efficient extraction and desorption.					
35352182	7	59	theme	0.0050-50 µg	1353:1364	arg1	pyrene					1382:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	1	60	mod	modified	243:250	arg1	fibers					231:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers	213:236	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	1	60	mod	modified	243:250	arg3	cryogel					267:273	a gelatin cryogel adsorbent	257:283	a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite	257:380	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	7	61	theme	benzo	1329:1333	arg1	anthracene					1337:1346	benzo(a)anthracene	1329:1346	benzo(a)anthracene	1329:1346	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	7	62	theme	0.0020-50 µg	1308:1319	arg1	L-1					1321:1323	0.0020-50 µg L-1	1308:1323	0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene	1308:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	7	62	theme	0.0020-50 µg	1308:1319	arg1	pyrene					1300:1305	pyrene	1300:1305	pyrene	1300:1305	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	3	63	theme	system	760:765	arg1	adsorbent					665:673	adsorbent	665:673	adsorbent	665:673	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	3	63	theme	system	760:765	arg1	phase					701:705	the solid phase	691:705	the solid phase of an in-syringe miniaturized solid-phase extraction system	691:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	4	64	theme	extract	849:855	arg1	hydrocarbons					896:907	extract and preconcentrate polycyclic aromatic hydrocarbons	849:907	extract and preconcentrate polycyclic aromatic hydrocarbons in water sample	849:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	4	65	theme	disposable	818:827	arg1	syringe					829:835	a disposable syringe	816:835	a disposable syringe	816:835	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	4	66	theme	water	912:916	arg1	sample					918:923	water sample	912:923	water sample	912:923	The adsorbent was packed into the needle hub of a disposable syringe and used to extract and preconcentrate polycyclic aromatic hydrocarbons in water sample.					
35352182	9	67	dep	98	1501:1502	arg1	to					1498:1499	to	1498:1499	to	1498:1499	Recoveries ranged from 89 to 98% with RSDs below 7%.					
35352182	7	68	theme	analysis	1178:1185	arg1	method					1187:1192	The developed analysis method	1164:1192	The developed analysis method	1164:1192	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	2	69	theme	adsorption	431:440	arg1	ability					442:448	the adsorption ability	427:448	the adsorption ability	427:448	The hybrid adsorption materials facilitated the adsorption ability toward polycyclic aromatic hydrocarbons and were entrapped into gelatin cryogel to be hierarchically coated on cellulose acetate fibers which helped to reduce the clogging problem of packed adsorbent.					
35352182	7	70	theme	dibenzo	1393:1399	arg1	anthracene					1405:1414	dibenzo(a,h)anthracene	1393:1414	anthracene	1405:1414	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	0	71	theme	iron-carboxylate	79:94	arg1	framework					110:118	an iron-carboxylate metal-organic framework	76:118	an iron-carboxylate metal-organic framework	76:118	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	3	72	theme	solid-phase	737:747	arg1	system					760:765	an in-syringe miniaturized solid-phase extraction system	710:765	an in-syringe miniaturized solid-phase extraction system	710:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	5	73	theme	best	1042:1045	arg1	performance					1058:1068	the best extraction performance	1038:1068	the best extraction performance	1038:1068	The fabricated porous composite adsorbent was characterized and extraction conditions were optimized to achieve the best extraction performance.					
35352182	1	74	theme	iron-carboxylate	302:317	arg1	framework					333:341	an iron-carboxylate metal-organic framework	299:341	an iron-carboxylate metal-organic framework	299:341	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35352182	7	75	dep	fluoranthene	1266:1277	arg1	b					1264:1264	b	1264:1264	b	1264:1264	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	3	76	theme	extraction	749:758	arg1	system					760:765	an in-syringe miniaturized solid-phase extraction system	710:765	an in-syringe miniaturized solid-phase extraction system	710:765	The composite adsorbent was employed as the solid phase of an in-syringe miniaturized solid-phase extraction system.					
35352182	0	77	link	hypercrosslinked	124:139	arg1	gelatin					159:165	hypercrosslinked polymer composite gelatin	124:165	hypercrosslinked polymer composite gelatin	124:165	In-syringe solid-phase extraction of polycyclic aromatic hydrocarbons using an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite gelatin cryogel-modified cellulose acetate adsorbent.					
35352182	5	78	theme	extraction	1047:1056	arg1	performance					1058:1068	the best extraction performance	1038:1068	the best extraction performance	1038:1068	The fabricated porous composite adsorbent was characterized and extraction conditions were optimized to achieve the best extraction performance.					
35352182	7	79	theme	a	1380:1380	arg1	pyrene					1382:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	0.0050-50 µg L-1 for benzo(a)pyrene	1353:1387	The developed analysis method provided a linear range of 0.020-50 µg L-1 for phenanthrene and benzo(b)fluoranthene, 0.010-50 µg L-1 for pyrene, 0.0020-50 µg L-1 for benzo(a)anthracene, and 0.0050-50 µg L-1 for benzo(a)pyrene and dibenzo(a,h)anthracene.					
35352182	1	80	theme	metal-organic	319:331	arg1	framework					333:341	an iron-carboxylate metal-organic framework	299:341	an iron-carboxylate metal-organic framework	299:341	Cellulose acetate fibers were modified with a gelatin cryogel adsorbent incorporating an iron-carboxylate metal-organic framework and hypercrosslinked polymer composite.					
35413309	3	0	theme	mixed	557:561	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	0	theme	mixed	557:561	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	0	theme	mixed	557:561	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	0	1	theme	wound	106:110	arg1	dressings					112:120	potential anti-infection wound dressings	81:120	potential anti-infection wound dressings	81:120	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	9	2	theme	fibers	1421:1426	arg1	adjustable					1432:1441	adjustable	1432:1441	adjustable	1432:1441	And the permeability of the fibers was adjustable.					
35413309	9	2	theme	fibers	1421:1426	arg1	permeability					1401:1412	the permeability	1397:1412	the permeability of the fibers	1397:1426	And the permeability of the fibers was adjustable.					
35413309	4	3	theme	emulsion	818:825	arg1	stability					835:843	the emulsion storage stability	814:843	the emulsion storage stability based on visual investigation	814:873	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	7	4	theme	hemolysis	1230:1238	arg1	test					1240:1243	In vitro hemolysis test	1221:1243	In vitro hemolysis test	1221:1243	In vitro hemolysis test indicated that nanofibers were hemocompatible.					
35413309	2	5	theme	anti-infection	335:348	arg1	development					359:369	anti-infection dressing development	335:369	anti-infection dressing development	335:369	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	2	6	theme	dressing	350:357	arg1	development					359:369	anti-infection dressing development	335:369	anti-infection dressing development	335:369	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	1	7	contain	possesses	188:196	arg1	citral					181:186	citral	181:186	citral	181:186	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	7	contain	possesses	188:196	arg2	agent					150:154	a natural antibacterial agent	126:154	a natural antibacterial agent with pleasant fragrance	126:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	7	contain	possesses	188:196	arg2	solubility					210:219	low aqueous solubility	198:219	low aqueous solubility	198:219	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	4	8	theme	regular	740:746	arg1	appearances					753:763	regular cube appearances	740:763	regular cube appearances	740:763	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	2	9	from	loading	240:246	arg1	nanofiber					263:271	hydrophilic nanofiber	251:271	hydrophilic nanofiber	251:271	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	7	10	theme	In	1221:1222	arg1	test					1240:1243	In vitro hemolysis test	1221:1243	In vitro hemolysis test	1221:1243	In vitro hemolysis test indicated that nanofibers were hemocompatible.					
35413309	4	11	theme	investigation	705:717	arg1	results					672:678	The results	668:678	The results of electronic microscope investigation	668:717	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	1	12	theme	low	198:200	arg1	solubility					210:219	low aqueous solubility	198:219	low aqueous solubility	198:219	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	12	theme	low	198:200	arg1	agent					150:154	a natural antibacterial agent	126:154	a natural antibacterial agent with pleasant fragrance	126:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	6	13	theme	good	1138:1141	arg1	performance					1157:1167	good antibacterial performance	1138:1167	good antibacterial performance	1138:1167	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	6	14	contain	possessed	1128:1136	arg1	nanofibers					1092:1101	nanofibers	1092:1101	nanofibers with high citral loading	1092:1126	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	6	14	contain	possessed	1128:1136	arg2	performance					1157:1167	good antibacterial performance	1138:1167	good antibacterial performance	1138:1167	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	7	15	dep	In	1221:1222	arg1	vitro					1224:1228	vitro	1224:1228	vitro	1224:1228	In vitro hemolysis test indicated that nanofibers were hemocompatible.					
35413309	1	16	theme	aqueous	202:208	arg1	solubility					210:219	low aqueous solubility	198:219	low aqueous solubility	198:219	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	16	theme	aqueous	202:208	arg1	agent					150:154	a natural antibacterial agent	126:154	a natural antibacterial agent with pleasant fragrance	126:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	0	17	theme	chitosan-based	14:27	arg1	electrospun					29:39	Carboxymethyl chitosan-based electrospun	0:39	Carboxymethyl chitosan-based electrospun	0:39	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	3	18	theme	aggerated	384:392	arg1	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	18	theme	aggerated	384:392	arg1	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	18	theme	aggerated	384:392	arg1	βCPs					445:448	βCPs	445:448	βCPs	445:448	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	19	theme	β-cyclodextrin-citral	394:414	arg1	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	19	theme	β-cyclodextrin-citral	394:414	arg1	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	19	theme	β-cyclodextrin-citral	394:414	arg1	βCPs					445:448	βCPs	445:448	βCPs	445:448	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	20	theme	phase	611:615	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	20	theme	phase	611:615	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	11	21	theme	promising	1587:1595	arg1	alternatives					1597:1608	promising alternatives	1587:1608	promising alternatives to conventional wound dressings	1587:1640	In summary, CMCS/PVA/βCPs/citral nanofibers seemed to be promising alternatives to conventional wound dressings.					
35413309	3	22	theme	citral	492:497	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	22	theme	citral	492:497	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	22	theme	citral	492:497	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	0	23	theme	Carboxymethyl	0:12	arg1	electrospun					29:39	Carboxymethyl chitosan-based electrospun	0:39	Carboxymethyl chitosan-based electrospun	0:39	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	3	24	theme	oil	607:609	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	24	theme	oil	607:609	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	1	25	with	agent	150:154	arg1	fragrance					170:178	fragrance	170:178	fragrance	170:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	4	26	theme	electronic	683:692	arg1	investigation					705:717	electronic microscope investigation	683:717	electronic microscope investigation	683:717	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	5	27	theme	bead-on-string	908:921	arg1	nanofibers					923:932	randomly oriented and bead-on-string nanofibers	886:932	randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed	886:964	Moreover, randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed could be obtained under optimized compositions and electrospinning parameters.					
35413309	11	28	theme	CMCS/PVA/βCPs/citral	1542:1561	arg1	nanofibers					1563:1572	CMCS/PVA/βCPs/citral nanofibers	1542:1572	CMCS/PVA/βCPs/citral nanofibers	1542:1572	In summary, CMCS/PVA/βCPs/citral nanofibers seemed to be promising alternatives to conventional wound dressings.					
35413309	4	29	theme	microscope	694:703	arg1	investigation					705:717	electronic microscope investigation	683:717	electronic microscope investigation	683:717	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	2	30	theme	emulsion	284:291	arg1	strategy					309:316	Pickering emulsion electrospinning strategy	274:316	Pickering emulsion electrospinning strategy	274:316	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	3	31	theme	dispersed	597:605	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	31	theme	dispersed	597:605	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	11	32	theme	wound	1626:1630	arg1	dressings					1632:1640	conventional wound dressings	1613:1640	conventional wound dressings	1613:1640	In summary, CMCS/PVA/βCPs/citral nanofibers seemed to be promising alternatives to conventional wound dressings.					
35413309	3	33	dep	aggerated	384:392	arg1	in-situ					376:382	in-situ	376:382	in-situ	376:382	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	34	theme	complex	426:432	arg1	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	34	theme	complex	426:432	arg1	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	34	theme	complex	426:432	arg1	βCPs					445:448	βCPs	445:448	βCPs	445:448	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	1	35	theme	natural	128:134	arg1	solubility					210:219	low aqueous solubility	198:219	low aqueous solubility	198:219	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	35	theme	natural	128:134	arg1	agent					150:154	a natural antibacterial agent	126:154	a natural antibacterial agent with pleasant fragrance	126:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	11	36	theme	conventional	1613:1624	arg1	dressings					1632:1640	conventional wound dressings	1613:1640	conventional wound dressings	1613:1640	In summary, CMCS/PVA/βCPs/citral nanofibers seemed to be promising alternatives to conventional wound dressings.					
35413309	3	37	theme	/polyvinyl	532:541	arg1	PVA					552:554	PVA	552:554	PVA	552:554	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	37	theme	/polyvinyl	532:541	arg1	alcohol					543:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol	503:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA)	503:555	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	0	38	theme	high	57:60	arg1	citral-loading					62:75	high citral-loading	57:75	high citral-loading for potential anti-infection wound dressings	57:120	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	4	39	theme	visual	854:859	arg1	investigation					861:873	visual investigation	854:873	visual investigation	854:873	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	8	40	theme	fibroblast	1375:1384	arg1	cells					1386:1390	mouse fibroblast cells	1369:1390	mouse fibroblast cells	1369:1390	In addition, both fiber matrix and citral could promote the proliferation of mouse fibroblast cells.					
35413309	6	41	theme	antibacterial	1143:1155	arg1	performance					1157:1167	good antibacterial performance	1138:1167	good antibacterial performance	1138:1167	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	3	42	theme	carboxymethyl	503:515	arg1	PVA					552:554	PVA	552:554	PVA	552:554	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	42	theme	carboxymethyl	503:515	arg1	alcohol					543:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol	503:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA)	503:555	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	43	used	used	456:459	arg2	βCPs					445:448	βCPs	445:448	βCPs	445:448	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	43	used	used	456:459	arg2	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	43	used	used	456:459	arg2	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	44	theme	continuous	629:638	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	44	theme	continuous	629:638	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	45	theme	CMCS	527:530	arg1	PVA					552:554	PVA	552:554	PVA	552:554	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	45	theme	CMCS	527:530	arg1	alcohol					543:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol	503:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA)	503:555	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	46	theme	emulsion	464:471	arg1	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	46	theme	emulsion	464:471	arg1	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	5	47	with	nanofibers	923:932	arg1	βCPs					939:942	βCPs	939:942	βCPs uniformly distributed	939:964	Moreover, randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed could be obtained under optimized compositions and electrospinning parameters.					
35413309	3	48	theme	inclusion	416:424	arg1	particles					434:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles	372:442	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs)	372:449	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	48	theme	inclusion	416:424	arg1	stabilizers					473:483	emulsion stabilizers	464:483	emulsion stabilizers	464:483	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	48	theme	inclusion	416:424	arg1	βCPs					445:448	βCPs	445:448	βCPs	445:448	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	2	49	theme	hydrophilic	251:261	arg1	nanofiber					263:271	hydrophilic nanofiber	251:271	hydrophilic nanofiber	251:271	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	1	50	theme	antibacterial	136:148	arg1	solubility					210:219	low aqueous solubility	198:219	low aqueous solubility	198:219	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	1	50	theme	antibacterial	136:148	arg1	agent					150:154	a natural antibacterial agent	126:154	a natural antibacterial agent with pleasant fragrance	126:178	As a natural antibacterial agent with pleasant fragrance, citral possesses low aqueous solubility.					
35413309	5	51	theme	electrospinning	1017:1031	arg1	parameters					1033:1042	electrospinning parameters	1017:1042	electrospinning parameters	1017:1042	Moreover, randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed could be obtained under optimized compositions and electrospinning parameters.					
35413309	6	52	with	nanofibers	1092:1101	arg1	loading					1120:1126	high citral loading	1108:1126	high citral loading	1108:1126	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	3	53	theme	outer	622:626	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	53	theme	outer	622:626	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	4	54	theme	cube	748:751	arg1	appearances					753:763	regular cube appearances	740:763	regular cube appearances	740:763	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	3	55	theme	phase	646:650	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	55	theme	phase	646:650	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	2	56	theme	citral	233:238	arg1	loading					240:246	citral loading	233:246	citral loading in hydrophilic nanofiber	233:271	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	4	57	theme	storage	827:833	arg1	stability					835:843	the emulsion storage stability	814:843	the emulsion storage stability based on visual investigation	814:873	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	8	58	theme	cells	1386:1390	arg1	proliferation					1352:1364	the proliferation	1348:1364	the proliferation of mouse fibroblast cells	1348:1390	In addition, both fiber matrix and citral could promote the proliferation of mouse fibroblast cells.					
35413309	3	59	theme	alcohol	543:549	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	59	theme	alcohol	543:549	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	59	theme	alcohol	543:549	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	60	theme	water	640:644	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	60	theme	water	640:644	arg1	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	10	61	theme	CMCS/PVA/βCPs/citral	1450:1469	arg1	nanofibers					1471:1480	CMCS/PVA/βCPs/citral nanofibers	1450:1480	CMCS/PVA/βCPs/citral nanofibers	1450:1480	Thus, CMCS/PVA/βCPs/citral nanofibers could potentially protect wound from infection.					
35413309	2	62	theme	electrospinning	293:307	arg1	strategy					309:316	Pickering emulsion electrospinning strategy	274:316	Pickering emulsion electrospinning strategy	274:316	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	4	63	theme	5.5 ± 2.2 μm	780:791	arg1	size					772:775	a size	770:775	a size	770:775	The results of electronic microscope investigation shown βCPs possessed regular cube appearances with a size of 5.5 ± 2.2 μm, which might improve the emulsion storage stability based on visual investigation.					
35413309	5	64	theme	optimized	990:998	arg1	compositions					1000:1011	optimized compositions	990:1011	optimized compositions	990:1011	Moreover, randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed could be obtained under optimized compositions and electrospinning parameters.					
35413309	0	65	theme	anti-infection	91:104	arg1	dressings					112:120	potential anti-infection wound dressings	81:120	potential anti-infection wound dressings	81:120	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	5	66	theme	oriented	895:902	arg1	nanofibers					923:932	randomly oriented and bead-on-string nanofibers	886:932	randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed	886:964	Moreover, randomly oriented and bead-on-string nanofibers with βCPs uniformly distributed could be obtained under optimized compositions and electrospinning parameters.					
35413309	3	67	used	used	578:581	arg2	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	67	used	used	578:581	arg2	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	67	used	used	578:581	arg2	"					651:651	outer "continuous water phase"	622:651	outer "continuous water phase"	622:651	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	68	theme	chitosan	517:524	arg1	PVA					552:554	PVA	552:554	PVA	552:554	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	68	theme	chitosan	517:524	arg1	alcohol					543:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol	503:549	carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA)	503:555	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	6	69	theme	citral	1113:1118	arg1	loading					1120:1126	high citral loading	1108:1126	high citral loading	1108:1126	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
35413309	0	70	theme	potential	81:89	arg1	dressings					112:120	potential anti-infection wound dressings	81:120	potential anti-infection wound dressings	81:120	Carboxymethyl chitosan-based electrospun nanofibers with high citral-loading for potential anti-infection wound dressings.					
35413309	3	71	theme	inner	590:594	arg1	solutions					563:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions	492:571	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	3	71	theme	inner	590:594	arg1	"					616:616	the inner "dispersed oil phase"	586:616	the inner "dispersed oil phase"	586:616	The in-situ aggerated β-cyclodextrin-citral inclusion complex particles (βCPs) were used as emulsion stabilizers, while citral and carboxymethyl chitosan (CMCS)/polyvinyl alcohol (PVA) mixed solutions were used as the inner "dispersed oil phase" and outer "continuous water phase", respectively.					
35413309	2	72	theme	Pickering	274:282	arg1	strategy					309:316	Pickering emulsion electrospinning strategy	274:316	Pickering emulsion electrospinning strategy	274:316	To improve citral loading in hydrophilic nanofiber, Pickering emulsion electrospinning strategy was proposed for anti-infection dressing development.					
35413309	8	73	theme	fiber	1310:1314	arg1	matrix					1316:1321	fiber matrix	1310:1321	fiber matrix	1310:1321	In addition, both fiber matrix and citral could promote the proliferation of mouse fibroblast cells.					
35413309	8	74	theme	mouse	1369:1373	arg1	cells					1386:1390	mouse fibroblast cells	1369:1390	mouse fibroblast cells	1369:1390	In addition, both fiber matrix and citral could promote the proliferation of mouse fibroblast cells.					
35413309	6	75	theme	high	1108:1111	arg1	loading					1120:1126	high citral loading	1108:1126	high citral loading	1108:1126	Despite volatilization during electrospinning, nanofibers with high citral loading possessed good antibacterial performance against Staphylococcus aureus and Escherichia coli.					
36434975	7	0	theme	P-enriched	1413:1422	arg1	amendment					1469:1477	a potential soil amendment	1452:1477	a potential soil amendment	1452:1477	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	0	theme	P-enriched	1413:1422	arg1	CCM					1424:1426	the P-enriched CCM	1409:1426	the P-enriched CCM (which could be used as a potential soil amendment)	1409:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	9	1	theme	target	1814:1819	arg1	pathogens					1831:1839	target bacterial pathogens	1814:1839	target bacterial pathogens	1814:1839	No detectable levels of target bacterial pathogens were observed.					
36434975	8	2	theme	trace	1651:1655	arg1	levels					1657:1662	trace levels (well below legislative limits)	1651:1694	trace levels (well below legislative limits) of heavy metals	1651:1710	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	3	dep	PCBs	1766:1769	arg1	e.g.					1760:1763	e.g.	1760:1763	e.g.	1760:1763	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	10	4	theme	Pot	1856:1858	arg1	trials					1860:1865	Pot trials	1856:1865	Pot trials	1856:1865	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	1	5	theme	future	183:188	arg1	availability					190:201	the predicted limited future availability	161:201	the predicted limited future availability	161:201	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	7	6	theme	quality	1387:1393	arg1	assessment					1395:1404	a quality assessment	1385:1404	a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment)	1385:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	7	theme	micropollutants	1587:1601	arg1	assessment					1546:1555	microbiological assessment	1530:1555	microbiological assessment	1530:1555	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	7	theme	micropollutants	1587:1601	arg1	quantification					1561:1574	quantification	1561:1574	quantification	1561:1574	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	7	theme	micropollutants	1587:1601	arg1	composition					1517:1527	elemental composition	1507:1527	elemental composition	1507:1527	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	2	8	theme	rural	542:546	arg1	setting					548:554	a rural setting	540:554	a rural setting	540:554	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	8	9	dep	pollutants	1748:1757	arg1	pharmaceuticals					1772:1786	pharmaceuticals	1772:1786	pharmaceuticals	1772:1786	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	9	dep	pollutants	1748:1757	arg1	PCBs					1766:1769	PCBs	1766:1769	PCBs	1766:1769	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	3	10	theme	continuous	724:733	arg1	self-backwashing					735:750	continuous self-backwashing	724:750	continuous self-backwashing	724:750	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	0	11	theme	performance	117:127	arg1	assessment					93:102	An integrated assessment	79:102	An integrated assessment of adsorbent performance and quality	79:139	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	1	12	theme	phosphate	211:219	arg1	availability					190:201	the predicted limited future availability	161:201	the predicted limited future availability	161:201	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	1	12	theme	phosphate	211:219	arg1	Eutrophication					142:155	Eutrophication	142:155	Eutrophication	142:155	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	0	13	theme	quality	133:139	arg1	assessment					93:102	An integrated assessment	79:102	An integrated assessment of adsorbent performance and quality	79:139	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	4	14	theme	PO43-	871:875	arg1	levels					877:882	low and high PO43- levels	858:882	low and high PO43- levels	858:882	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	4	15	from	levels	877:882	arg1	conditions					838:847	'real' conditions	831:847	'real' conditions (both at low and high PO43- levels)	831:883	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	3	16	theme	enhanced	575:582	arg1	filtration					598:607	enhanced gravitational filtration	575:607	enhanced gravitational filtration	575:607	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	8	17	theme	metals	1705:1710	arg1	levels					1657:1662	trace levels (well below legislative limits)	1651:1694	trace levels (well below legislative limits) of heavy metals	1651:1710	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	17	theme	metals	1705:1710	arg1	levels					1730:1735	extremely low levels	1716:1735	extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals)	1716:1787	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	17	theme	metals	1705:1710	arg1	present					1642:1648	∼2.5% P2O5 present	1631:1648	∼2.5% P2O5 present	1631:1648	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	7	18	theme	microbiological	1530:1544	arg1	assessment					1546:1555	microbiological assessment	1530:1555	microbiological assessment	1530:1555	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	5	19	dep	harvested	1166:1174	arg1	%					1192:1192	more than 50%	1180:1192	more than 50%	1180:1192	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	5	20	theme	PO43-	1205:1209	arg1	levels					1211:1216	higher PO43- levels	1198:1216	higher PO43- levels	1198:1216	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	10	21	theme	higher	1947:1952	arg1	matter					1964:1969	higher plant dry matter and P concentration	1947:1989	matter	1964:1969	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	6	22	theme	Surface	1219:1225	arg1	microprecipitation					1227:1244	Surface microprecipitation	1219:1244	Surface microprecipitation	1219:1244	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	22	theme	Surface	1219:1225	arg1	mechanisms					1321:1330	the main PO43- adsorption mechanisms	1295:1330	the main PO43- adsorption mechanisms	1295:1330	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	22	theme	Surface	1219:1225	arg1	complexation					1263:1274	inner-sphere complexation	1250:1274	inner-sphere complexation	1250:1274	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	5	23	theme	phosphate	1013:1021	arg1	concentrations					1023:1036	low phosphate concentrations	1009:1036	low phosphate concentrations	1009:1036	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	2	24	theme	wastewater	477:486	arg1	effluent					488:495	wastewater effluent	477:495	wastewater effluent	477:495	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	10	25	theme	adsorbent	1928:1936	arg1	CCM					1924:1926	the CCM adsorbent	1920:1936	the CCM adsorbent	1920:1936	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	0	26	theme	fertiliser	59:68	arg1	product					70:76	a fertiliser product	57:76	a fertiliser product	57:76	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	3	27	theme	adsorption	617:626	arg1	media					628:632	adsorption media	617:632	adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing	617:750	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	8	28	theme	organic	1740:1746	arg1	pollutants					1748:1757	organic pollutants	1740:1757	organic pollutants (e.g., PCBs, pharmaceuticals)	1740:1787	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	1	29	theme	predicted	165:173	arg1	availability					190:201	the predicted limited future availability	161:201	the predicted limited future availability	161:201	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	2	30	theme	filtration/adsorption	507:527	arg1	process					529:535	a filtration/adsorption process	505:535	a filtration/adsorption process in a rural setting	505:554	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	10	31	theme	dry	1960:1962	arg1	matter					1964:1969	higher plant dry matter and P concentration	1947:1989	matter	1964:1969	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	0	32	theme	integrated	82:91	arg1	assessment					93:102	An integrated assessment	79:102	An integrated assessment of adsorbent performance and quality	79:139	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	5	33	theme	effluent	1061:1068	arg1	level					1076:1080	the residual effluent PO43- level	1048:1080	the residual effluent PO43- level	1048:1080	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	10	34	theme	kinetic	2051:2057	arg1	pattern					2059:2065	a slow-release kinetic pattern	2036:2065	a slow-release kinetic pattern	2036:2065	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	11	35	theme	FILTRAFLOTM-P	2109:2121	arg1	reactor					2129:2135	the FILTRAFLOTM-P pilot reactor	2105:2135	the FILTRAFLOTM-P pilot reactor	2105:2135	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	0	36	from	wastewater	36:45	arg1	recovery					22:29	Pilot-scale phosphate recovery	0:29	Pilot-scale phosphate recovery from wastewater	0:45	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	11	37	theme	high	2141:2144	arg1	potential					2146:2154	high potential	2141:2154	high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste	2141:2256	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	11	38	contain	has	2137:2139	arg1	CCM					2091:2093	CCM	2091:2093	CCM used with the FILTRAFLOTM-P pilot reactor	2091:2135	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	11	38	contain	has	2137:2139	arg2	potential					2146:2154	high potential	2141:2154	high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste	2141:2256	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	0	39	theme	Pilot-scale	0:10	arg1	recovery					22:29	Pilot-scale phosphate recovery	0:29	Pilot-scale phosphate recovery from wastewater	0:45	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	1	40	theme	recovery	279:286	arg1	technologies					288:299	phosphorus (P) recovery technologies	264:299	phosphorus (P) recovery technologies	264:299	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	2	41	theme	FILTRAFLOTM-P	420:432	arg1	reactor					434:440	FILTRAFLOTM-P reactor	420:440	FILTRAFLOTM-P reactor	420:440	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	2	41	theme	FILTRAFLOTM-P	420:432	arg1	technology					408:417	a novel pilot-scale technology	388:417	a novel pilot-scale technology (FILTRAFLOTM-P reactor)	388:441	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	7	42	theme	potential	1454:1462	arg1	amendment					1469:1477	a potential soil amendment	1452:1477	a potential soil amendment	1452:1477	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	42	theme	potential	1454:1462	arg1	CCM					1424:1426	the P-enriched CCM	1409:1426	the P-enriched CCM (which could be used as a potential soil amendment)	1409:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	4	43	theme	final	964:968	arg1	effluent					970:977	final effluent	964:977	final effluent	964:977	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	9	44	theme	pathogens	1831:1839	arg1	levels					1804:1809	No detectable levels	1790:1809	No detectable levels of target bacterial pathogens	1790:1839	No detectable levels of target bacterial pathogens were observed.					
36434975	3	45	theme	novel	643:647	arg1	carapace					671:678	a novel KOH deacetylated crab carapace	641:678	a novel KOH deacetylated crab carapace	641:678	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	2	46	theme	novel	390:394	arg1	reactor					434:440	FILTRAFLOTM-P reactor	420:440	FILTRAFLOTM-P reactor	420:440	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	2	46	theme	novel	390:394	arg1	technology					408:417	a novel pilot-scale technology	388:417	a novel pilot-scale technology (FILTRAFLOTM-P reactor)	388:441	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	6	47	theme	EDX	1353:1355	arg1	mapping					1367:1373	EDX elemental mapping	1353:1373	EDX elemental mapping	1353:1373	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	0	48	dep	create	50:55	arg1	assessment					93:102	An integrated assessment	79:102	An integrated assessment of adsorbent performance and quality	79:139	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	4	49	dep	levels	877:882	arg1	both					850:853	both	850:853	both	850:853	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	5	50	theme	sensitive	1109:1117	arg1	bodies					1125:1130	sensitive water bodies	1109:1130	sensitive water bodies	1109:1130	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	2	51	from	process	529:535	arg1	setting					548:554	a rural setting	540:554	a rural setting	540:554	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	3	52	theme	deacetylated	653:664	arg1	carapace					671:678	a novel KOH deacetylated crab carapace	641:678	a novel KOH deacetylated crab carapace	641:678	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	7	53	theme	CCM	1424:1426	arg1	assessment					1395:1404	a quality assessment	1385:1404	a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment)	1385:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	10	54	theme	CCM	1924:1926	arg1	addition					1908:1915	the addition	1904:1915	the addition of the CCM adsorbent	1904:1936	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	9	55	theme	detectable	1793:1802	arg1	levels					1804:1809	No detectable levels	1790:1809	No detectable levels of target bacterial pathogens	1790:1839	No detectable levels of target bacterial pathogens were observed.					
36434975	8	56	theme	∼2.5	1631:1634	arg1	%					1635:1635	%	1635:1635	%	1635:1635	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	1	57	theme	phosphorus	264:273	arg1	technologies					288:299	phosphorus (P) recovery technologies	264:299	phosphorus (P) recovery technologies	264:299	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	10	58	theme	unfertilised	2008:2019	arg1	controls					2021:2028	unfertilised controls	2008:2028	unfertilised controls	2008:2028	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	3	59	theme	chitosan-calcite	686:701	arg1	material					703:710	chitosan-calcite material	686:710	chitosan-calcite material (CCM)	686:716	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	3	59	theme	chitosan-calcite	686:701	arg1	CCM					713:715	CCM	713:715	CCM	713:715	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	8	60	theme	P2O5	1637:1640	arg1	present					1642:1648	∼2.5% P2O5 present	1631:1648	∼2.5% P2O5 present	1631:1648	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	1	61	theme	P	276:276	arg1	technologies					288:299	phosphorus (P) recovery technologies	264:299	phosphorus (P) recovery technologies	264:299	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	4	62	theme	low	858:860	arg1	levels					877:882	low and high PO43- levels	858:882	low and high PO43- levels	858:882	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	9	63	theme	bacterial	1821:1829	arg1	pathogens					1831:1839	target bacterial pathogens	1814:1839	target bacterial pathogens	1814:1839	No detectable levels of target bacterial pathogens were observed.					
36434975	1	64	theme	limited	175:181	arg1	availability					190:201	the predicted limited future availability	161:201	the predicted limited future availability	161:201	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	4	65	theme	real	832:835	arg1	conditions					838:847	'real' conditions	831:847	'real' conditions (both at low and high PO43- levels)	831:883	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	1	66	theme	remote	315:320	arg1	regions					322:328	remote regions	315:328	remote regions	315:328	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	7	67	theme	organic	1579:1585	arg1	micropollutants					1587:1601	organic micropollutants	1579:1601	organic micropollutants	1579:1601	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	11	68	theme	bio-based	2228:2236	arg1	management					2238:2247	bio-based management	2228:2247	bio-based management of waste	2228:2256	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	1	69	theme	rock	206:209	arg1	phosphate					211:219	rock phosphate	206:219	rock phosphate	206:219	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	3	70	theme	gravitational	584:596	arg1	filtration					598:607	enhanced gravitational filtration	575:607	enhanced gravitational filtration	575:607	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	8	71	theme	legislative	1676:1686	arg1	limits					1688:1693	legislative limits	1676:1693	legislative limits	1676:1693	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	3	72	dep	media	628:632	arg1	based					680:684	based	680:684	based chitosan-calcite material (CCM)	680:716	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	11	73	theme	resource	2206:2213	arg1	recovery					2215:2222	resource recovery	2206:2222	resource recovery	2206:2222	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	6	74	theme	inner-sphere	1250:1261	arg1	mechanisms					1321:1330	the main PO43- adsorption mechanisms	1295:1330	the main PO43- adsorption mechanisms	1295:1330	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	74	theme	inner-sphere	1250:1261	arg1	complexation					1263:1274	inner-sphere complexation	1250:1274	inner-sphere complexation	1250:1274	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	74	theme	inner-sphere	1250:1261	arg1	microprecipitation					1227:1244	Surface microprecipitation	1219:1244	Surface microprecipitation	1219:1244	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	5	75	theme	residual	1052:1059	arg1	level					1076:1080	the residual effluent PO43- level	1048:1080	the residual effluent PO43- level	1048:1080	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	4	76	theme	high	866:869	arg1	levels					877:882	low and high PO43- levels	858:882	low and high PO43- levels	858:882	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	5	77	theme	higher	1198:1203	arg1	levels					1211:1216	higher PO43- levels	1198:1216	higher PO43- levels	1198:1216	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	5	78	theme	low	1009:1011	arg1	concentrations					1023:1036	low phosphate concentrations	1009:1036	low phosphate concentrations	1009:1036	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	8	79	theme	heavy	1699:1703	arg1	metals					1705:1710	heavy metals	1699:1710	heavy metals	1699:1710	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	7	80	theme	elemental	1507:1515	arg1	composition					1517:1527	elemental composition	1507:1527	elemental composition	1507:1527	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	4	81	theme	adsorbent	928:936	arg1	effectiveness					907:919	the effectiveness	903:919	the effectiveness of the adsorbent to recover phosphate from final effluent	903:977	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	6	82	theme	PO43-	1304:1308	arg1	microprecipitation					1227:1244	Surface microprecipitation	1219:1244	Surface microprecipitation	1219:1244	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	82	theme	PO43-	1304:1308	arg1	mechanisms					1321:1330	the main PO43- adsorption mechanisms	1295:1330	the main PO43- adsorption mechanisms	1295:1330	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	82	theme	PO43-	1304:1308	arg1	complexation					1263:1274	inner-sphere complexation	1250:1274	inner-sphere complexation	1250:1274	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	3	83	with	media	628:632	arg1	self-backwashing					735:750	continuous self-backwashing	724:750	continuous self-backwashing	724:750	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	1	84	theme	recovery	331:338	arg1	solutions					340:348	recovery solutions	331:348	recovery solutions	331:348	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	8	85	theme	low	1726:1728	arg1	levels					1730:1735	extremely low levels	1716:1735	extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals)	1716:1787	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	86	dep	limits	1688:1693	arg1	well					1665:1668	well	1665:1668	well	1665:1668	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	6	87	theme	adsorption	1310:1319	arg1	microprecipitation					1227:1244	Surface microprecipitation	1219:1244	Surface microprecipitation	1219:1244	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	87	theme	adsorption	1310:1319	arg1	mechanisms					1321:1330	the main PO43- adsorption mechanisms	1295:1330	the main PO43- adsorption mechanisms	1295:1330	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	87	theme	adsorption	1310:1319	arg1	complexation					1263:1274	inner-sphere complexation	1250:1274	inner-sphere complexation	1250:1274	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	5	88	theme	EU	1096:1097	arg1	mg/L					1090:1093	1 mg/L	1088:1093	1 mg/L (EU limit for sensitive water bodies)	1088:1131	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	5	88	theme	EU	1096:1097	arg1	limit					1099:1103	EU limit	1096:1103	EU limit for sensitive water bodies	1096:1130	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	10	89	theme	plant	1954:1958	arg1	matter					1964:1969	higher plant dry matter and P concentration	1947:1989	matter	1964:1969	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	6	90	theme	main	1299:1302	arg1	microprecipitation					1227:1244	Surface microprecipitation	1219:1244	Surface microprecipitation	1219:1244	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	90	theme	main	1299:1302	arg1	mechanisms					1321:1330	the main PO43- adsorption mechanisms	1295:1330	the main PO43- adsorption mechanisms	1295:1330	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	6	90	theme	main	1299:1302	arg1	complexation					1263:1274	inner-sphere complexation	1250:1274	inner-sphere complexation	1250:1274	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	5	91	theme	PO43-	1070:1074	arg1	level					1076:1080	the residual effluent PO43- level	1048:1080	the residual effluent PO43- level	1048:1080	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	8	92	theme	pollutants	1748:1757	arg1	levels					1657:1662	trace levels (well below legislative limits)	1651:1694	trace levels (well below legislative limits) of heavy metals	1651:1710	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	92	theme	pollutants	1748:1757	arg1	levels					1730:1735	extremely low levels	1716:1735	extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals)	1716:1787	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	8	92	theme	pollutants	1748:1757	arg1	present					1642:1648	∼2.5% P2O5 present	1631:1648	∼2.5% P2O5 present	1631:1648	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	0	93	theme	adsorbent	107:115	arg1	performance					117:127	adsorbent performance	107:127	adsorbent performance	107:127	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	0	94	theme	phosphate	12:20	arg1	recovery					22:29	Pilot-scale phosphate recovery	0:29	Pilot-scale phosphate recovery from wastewater	0:45	Pilot-scale phosphate recovery from wastewater to create a fertiliser product: An integrated assessment of adsorbent performance and quality.					
36434975	1	95	theme	technologies	288:299	arg1	development					249:259	the increased development	235:259	the increased development of phosphorus (P) recovery technologies	235:299	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	10	96	theme	slow-release	2038:2049	arg1	pattern					2059:2065	a slow-release kinetic pattern	2036:2065	a slow-release kinetic pattern	2036:2065	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	2	97	theme	pilot-scale	396:406	arg1	reactor					434:440	FILTRAFLOTM-P reactor	420:440	FILTRAFLOTM-P reactor	420:440	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	2	97	theme	pilot-scale	396:406	arg1	technology					408:417	a novel pilot-scale technology	388:417	a novel pilot-scale technology (FILTRAFLOTM-P reactor)	388:441	Here, we report on a novel pilot-scale technology (FILTRAFLOTM-P reactor) to recover phosphate (PO43-) from wastewater effluent through a filtration/adsorption process in a rural setting.					
36434975	6	98	theme	elemental	1357:1365	arg1	mapping					1367:1373	EDX elemental mapping	1353:1373	EDX elemental mapping	1353:1373	Surface microprecipitation and inner-sphere complexation were postulated as the main PO43- adsorption mechanisms through XRD, XPS and EDX elemental mapping.					
36434975	7	99	theme	soil	1464:1467	arg1	amendment					1469:1477	a potential soil amendment	1452:1477	a potential soil amendment	1452:1477	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	99	theme	soil	1464:1467	arg1	CCM					1424:1426	the P-enriched CCM	1409:1426	the P-enriched CCM (which could be used as a potential soil amendment)	1409:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	5	100	theme	High	980:983	arg1	removal					985:991	High removal	980:991	High removal	980:991	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	11	101	theme	waste	2252:2256	arg1	management					2238:2247	bio-based management	2228:2247	bio-based management of waste	2228:2256	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	11	102	theme	pilot	2123:2127	arg1	reactor					2129:2135	the FILTRAFLOTM-P pilot reactor	2105:2135	the FILTRAFLOTM-P pilot reactor	2105:2135	This study showed that CCM used with the FILTRAFLOTM-P pilot reactor has high potential to recover phosphate from effluents and encourage resource recovery via bio-based management of waste.					
36434975	7	103	used	used	1444:1447	arg2	amendment					1469:1477	a potential soil amendment	1452:1477	a potential soil amendment	1452:1477	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	7	103	used	used	1444:1447	arg2	CCM					1424:1426	the P-enriched CCM	1409:1426	the P-enriched CCM (which could be used as a potential soil amendment)	1409:1478	Further, a quality assessment of the P-enriched CCM (which could be used as a potential soil amendment) was undertaken to consider elemental composition, microbiological assessment and quantification of organic micropollutants.					
36434975	3	104	theme	crab	666:669	arg1	carapace					671:678	a novel KOH deacetylated crab carapace	641:678	a novel KOH deacetylated crab carapace	641:678	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	8	105	theme	Quality	1604:1610	arg1	analysis					1612:1619	Quality analysis	1604:1619	Quality analysis	1604:1619	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
36434975	5	106	theme	water	1119:1123	arg1	bodies					1125:1130	sensitive water bodies	1109:1130	sensitive water bodies	1109:1130	High removal was achieved at low phosphate concentrations, bringing the residual effluent PO43- level below 1 mg/L (EU limit for sensitive water bodies), while phosphate was efficiently harvested (at more than 50%) at higher PO43- levels.					
36434975	3	107	theme	KOH	649:651	arg1	carapace					671:678	a novel KOH deacetylated crab carapace	641:678	a novel KOH deacetylated crab carapace	641:678	This unit employs enhanced gravitational filtration through adsorption media (here, a novel KOH deacetylated crab carapace based chitosan-calcite material (CCM)) with continuous self-backwashing.					
36434975	1	108	theme	increased	239:247	arg1	development					249:259	the increased development	235:259	the increased development of phosphorus (P) recovery technologies	235:299	Eutrophication and the predicted limited future availability of rock phosphate has triggered the increased development of phosphorus (P) recovery technologies, however, for remote regions, recovery solutions are still limited.					
36434975	10	109	theme	P	1975:1975	arg1	concentration					1977:1989	higher plant dry matter and P concentration	1947:1989	concentration	1977:1989	Pot trials showed that ryegrass cultivated with the addition of the CCM adsorbent achieved higher plant dry matter and P concentration when compared to unfertilised controls, with a slow-release kinetic pattern.					
36434975	4	110	theme	FILTRAFLOTM-P	792:804	arg1	unit					806:809	the FILTRAFLOTM-P unit	788:809	the FILTRAFLOTM-P unit	788:809	Trials were designed to assess how the FILTRAFLOTM-P unit would operate under 'real' conditions (both at low and high PO43- levels), and to ascertain the effectiveness of the adsorbent to recover phosphate from final effluent.					
36434975	8	111	theme	%	1635:1635	arg1	present					1642:1648	∼2.5% P2O5 present	1631:1648	∼2.5% P2O5 present	1631:1648	Quality analysis indicated ∼2.5% P2O5 present, trace levels (well below legislative limits) of heavy metals and extremely low levels of organic pollutants (e.g., PCBs, pharmaceuticals).					
35913000	2	0	theme	presumed	333:340	arg1	impact					342:347	their presumed impact	327:347	their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems	327:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	4	1	theme	urban	966:970	arg1	diet					972:975	the urban diet	962:975	the urban diet	962:975	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	2	2	from	host	545:548	arg1	knowledge					460:468	our overall knowledge	448:468	our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host	448:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	3	3	theme	differential	672:683	arg1	effect					685:690	the potential differential effect	658:690	the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura)	658:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	4	4	theme	metabolomes	1036:1046	arg1	profiles					1006:1013	the profiles	1002:1013	the profiles of the GM and tissue metabolomes	1002:1046	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	3	5	from	effect	685:690	arg1	GM					757:758	the GM	753:758	the GM	753:758	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	5	from	effect	685:690	arg1	profiles					775:782	the metabolic profiles	761:782	the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin	761:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	5	from	effect	685:690	arg1	factors					882:888	inflammatory factors	869:888	inflammatory factors in urban-caught mourning doves (Zenaida macroura)	869:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	1	6	theme	many	183:186	arg1	species					194:200	many avian species	183:200	many avian species	183:200	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	2	7	theme	expression	521:530	arg1	role					477:480	the role	473:480	the role of gut microbiome (GM) and metabolomic expression in the avian host	473:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	7	8	theme	inflammatory	1701:1712	arg1	markers					1714:1720	plasma inflammatory markers	1694:1720	plasma inflammatory markers	1694:1720	These differences were largely not reflected in the surveyed metabolomes and plasma inflammatory markers.					
35913000	3	9	theme	urban	698:702	arg1	modeled					704:710	an urban modeled versus control (i.e., bird seed) diet	695:748	modeled	704:710	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	1	10	from	subsidies	250:258	arg1	environments					269:280	built environments	263:280	built environments	263:280	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	3	11	dep	seed	739:742	arg1	i.e.					728:731	i.e.	728:731	i.e.	728:731	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	6	12	theme	GM	1413:1414	arg1	composition					1394:1404	The composition	1390:1404	The composition of the GM	1390:1414	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	6	12	theme	GM	1413:1414	arg1	dissimilar					1434:1443	dissimilar	1434:1443	dissimilar	1434:1443	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	6	13	with	diets	1453:1457	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	2	14	from	role	477:480	arg1	host					545:548	the avian host	535:548	the avian host	535:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	8	15	theme	urban	1791:1795	arg1	doves					1797:1801	urban doves	1791:1801	urban doves	1791:1801	This research supports the notion that the microbial composition in urban doves is impacted by diet, though may only weakly associate with host physiology.					
35913000	6	16	theme	urban-fed	1600:1608	arg1	birds					1610:1614	the urban-fed birds	1596:1614	the urban-fed birds	1596:1614	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	3	17	theme	diet	745:748	arg1	effect					685:690	the potential differential effect	658:690	the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura)	658:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	1	18	from	access	218:223	arg1	environments					269:280	built environments	263:280	built environments	263:280	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	3	19	theme	metabolic	765:773	arg1	profiles					775:782	the metabolic profiles	761:782	the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin	761:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	6	20	theme	greater	1465:1471	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	5	21	theme	4-wk-diet	1168:1176	arg1	period					1178:1183	a 4-wk-diet period	1166:1183	a 4-wk-diet period	1166:1183	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	8	22	theme	microbial	1766:1774	arg1	composition					1776:1786	the microbial composition	1762:1786	the microbial composition in urban doves	1762:1801	This research supports the notion that the microbial composition in urban doves is impacted by diet, though may only weakly associate with host physiology.					
35913000	2	23	theme	microbiome	489:498	arg1	role					477:480	the role	473:480	the role of gut microbiome (GM) and metabolomic expression in the avian host	473:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	5	24	theme	inflammatory	1354:1365	arg1	markers					1367:1373	inflammatory markers	1354:1373	inflammatory markers	1354:1373	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	4	25	theme	seed	1149:1152	arg1	diet					1154:1157	a seed diet	1147:1157	a seed diet	1147:1157	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	2	26	theme	intestinal	377:386	arg1	tract					388:392	the intestinal tract	373:392	the intestinal tract	373:392	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	0	27	theme	seed	96:99	arg1	diet					101:104	a seed diet	94:104	a seed diet in mourning doves	94:122	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	6	28	theme	Sanguibacter	1550:1561	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	2	29	theme	systems	439:445	arg1	profiles					408:415	metabolic profiles	398:415	metabolic profiles of host physiological systems	398:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	29	theme	systems	439:445	arg1	microbes					352:359	microbes	352:359	microbes harbored in the intestinal tract	352:392	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	30	dep	intakes	315:321	arg1	relation					286:293	relation	286:293	relation	286:293	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	31	theme	host	420:423	arg1	systems					439:445	host physiological systems	420:445	host physiological systems	420:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	5	32	theme	large	1202:1206	arg1	intestine					1208:1216	the large intestine	1198:1216	the large intestine	1198:1216	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	3	33	theme	muscle	823:828	arg1	tissues					830:836	liver, adipose, kidney, and muscle tissues	795:836	liver, adipose, kidney, and muscle tissues	795:836	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	0	34	theme	gut	40:42	arg1	microbiome					44:53	the gut microbiome	36:53	the gut microbiome	36:53	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	3	35	theme	circulating	843:853	arg1	endotoxin					855:863	circulating endotoxin	843:863	circulating endotoxin	843:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	5	36	theme	plasma	1299:1304	arg1	homogenates					1317:1327	plasma and tissue homogenates	1299:1327	plasma and tissue homogenates	1299:1327	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	1	37	theme	increased	208:216	arg1	access					218:223	increased access	208:223	increased access to human refuse	208:239	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	3	38	theme	urban-caught	893:904	arg1	Zenaida					922:928	Zenaida	922:928	Zenaida	922:928	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	38	theme	urban-caught	893:904	arg1	doves					915:919	urban-caught mourning doves	893:919	urban-caught mourning doves (Zenaida macroura)	893:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	39	theme	potential	662:670	arg1	effect					685:690	the potential differential effect	658:690	the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura)	658:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	2	40	from	intakes	315:321	arg1	microbes					352:359	microbes	352:359	microbes harbored in the intestinal tract	352:392	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	40	from	intakes	315:321	arg1	profiles					408:415	metabolic profiles	398:415	metabolic profiles of host physiological systems	398:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	5	41	theme	circulating	1334:1344	arg1	LPS					1346:1348	circulating LPS	1334:1348	circulating LPS	1334:1348	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	1	42	theme	food	245:248	arg1	subsidies					250:258	food subsidies	245:258	food subsidies in built environments	245:280	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	4	43	theme	tissue	1029:1034	arg1	metabolomes					1036:1046	the GM and tissue metabolomes	1018:1046	metabolomes	1036:1046	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	2	44	theme	mammals	587:593	arg1	understanding					570:582	our understanding	566:582	our understanding of mammals	566:593	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	45	from	impact	342:347	arg1	microbes					352:359	microbes	352:359	microbes harbored in the intestinal tract	352:392	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	45	from	impact	342:347	arg1	profiles					408:415	metabolic profiles	398:415	metabolic profiles of host physiological systems	398:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	5	46	theme	tissue	1310:1315	arg1	homogenates					1317:1327	plasma and tissue homogenates	1299:1327	plasma and tissue homogenates	1299:1327	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	2	47	theme	such	298:301	arg1	intakes					315:321	such nutritional intakes	298:321	such nutritional intakes	298:321	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	6	48	from	LPS	1589:1591	arg1	birds					1610:1614	the urban-fed birds	1596:1614	the urban-fed birds	1596:1614	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	7	49	theme	plasma	1694:1699	arg1	markers					1714:1720	plasma inflammatory markers	1694:1720	plasma inflammatory markers	1694:1720	These differences were largely not reflected in the surveyed metabolomes and plasma inflammatory markers.					
35913000	3	50	from	profiles	775:782	arg1	Zenaida					922:928	Zenaida	922:928	Zenaida	922:928	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	50	from	profiles	775:782	arg1	doves					915:919	urban-caught mourning doves	893:919	urban-caught mourning doves (Zenaida macroura)	893:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	51	theme	control	719:725	arg1	diet					745:748	an urban modeled versus control (i.e., bird seed) diet	695:748	diet	745:748	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	0	52	theme	mourning	109:116	arg1	doves					118:122	mourning doves	109:122	mourning doves	109:122	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	1	53	theme	avian	188:192	arg1	species					194:200	many avian species	183:200	many avian species	183:200	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	2	54	theme	metabolomic	509:519	arg1	expression					521:530	metabolomic expression	509:530	metabolomic expression	509:530	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	4	55	theme	GM	1022:1023	arg1	metabolomes					1036:1046	the GM and tissue metabolomes	1018:1046	metabolomes	1036:1046	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	3	56	theme	modeled	704:710	arg1	effect					685:690	the potential differential effect	658:690	the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura)	658:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	8	57	theme	host	1862:1865	arg1	physiology					1867:1876	host physiology	1862:1876	host physiology	1862:1876	This research supports the notion that the microbial composition in urban doves is impacted by diet, though may only weakly associate with host physiology.					
35913000	2	58	dep	lags	550:553	arg1	behind					559:564	behind	559:564	lags far behind our understanding of mammals	550:593	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	6	59	theme	Sanguibacteraceae	1513:1529	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	2	60	theme	avian	539:543	arg1	host					545:548	the avian host	535:548	the avian host	535:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	0	61	from	diet	101:104	arg1	doves					118:122	mourning doves	109:122	mourning doves	109:122	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	4	62	theme	proinflammatory	1097:1111	arg1	factors					1113:1119	proinflammatory factors	1097:1119	proinflammatory factors	1097:1119	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	6	63	theme	Erysipelatoclostridiaceae	1486:1510	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	3	64	theme	plasma	787:792	arg1	GM					757:758	the GM	753:758	the GM	753:758	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	64	theme	plasma	787:792	arg1	profiles					775:782	the metabolic profiles	761:782	the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin	761:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	64	theme	plasma	787:792	arg1	factors					882:888	inflammatory factors	869:888	inflammatory factors in urban-caught mourning doves (Zenaida macroura)	869:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	4	65	theme	plasma	1061:1066	arg1	lipopolysaccharide					1068:1085	plasma lipopolysaccharide	1061:1085	plasma lipopolysaccharide (LPS)	1061:1091	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	4	65	theme	plasma	1061:1066	arg1	LPS					1088:1090	LPS	1088:1090	LPS	1088:1090	We hypothesized that the urban diet would differently impact the profiles of the GM and tissue metabolomes and increase plasma lipopolysaccharide (LPS) and proinflammatory factors compared with animals fed a seed diet.					
35913000	0	66	theme	metabolomic	59:69	arg1	profiles					71:78	metabolomic profiles	59:78	metabolomic profiles	59:78	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	7	67	theme	surveyed	1669:1676	arg1	metabolomes					1678:1688	the surveyed metabolomes	1665:1688	the surveyed metabolomes	1665:1688	These differences were largely not reflected in the surveyed metabolomes and plasma inflammatory markers.					
35913000	2	68	theme	role	477:480	arg1	knowledge					460:468	our overall knowledge	448:468	our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host	448:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	1	69	theme	food	149:152	arg1	quality					154:160	food quality	149:160	food quality	149:160	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	3	70	theme	adipose	802:808	arg1	tissues					830:836	liver, adipose, kidney, and muscle tissues	795:836	liver, adipose, kidney, and muscle tissues	795:836	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	8	71	from	composition	1776:1786	arg1	doves					1797:1801	urban doves	1791:1801	urban doves	1791:1801	This research supports the notion that the microbial composition in urban doves is impacted by diet, though may only weakly associate with host physiology.					
35913000	6	72	theme	circulating	1577:1587	arg1	LPS					1589:1591	circulating LPS	1577:1591	circulating LPS in the urban-fed birds	1577:1614	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	3	73	theme	liver	795:799	arg1	tissues					830:836	liver, adipose, kidney, and muscle tissues	795:836	liver, adipose, kidney, and muscle tissues	795:836	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	74	from	factors	882:888	arg1	Zenaida					922:928	Zenaida	922:928	Zenaida	922:928	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	74	from	factors	882:888	arg1	doves					915:919	urban-caught mourning doves	893:919	urban-caught mourning doves (Zenaida macroura)	893:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	2	75	theme	gut	485:487	arg1	microbiome					489:498	gut microbiome	485:498	gut microbiome (GM)	485:503	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	75	theme	gut	485:487	arg1	GM					501:502	GM	501:502	GM	501:502	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	2	76	from	knowledge	460:468	arg1	host					545:548	the avian host	535:548	the avian host	535:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	0	77	theme	urban	3:7	arg1	diet					9:12	An urban diet	0:12	An urban diet	0:12	An urban diet differentially alters the gut microbiome and metabolomic profiles compared with a seed diet in mourning doves.					
35913000	3	78	theme	kidney	811:816	arg1	tissues					830:836	liver, adipose, kidney, and muscle tissues	795:836	liver, adipose, kidney, and muscle tissues	795:836	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	2	79	theme	physiological	425:437	arg1	systems					439:445	host physiological systems	420:445	host physiological systems	420:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	1	80	theme	built	263:267	arg1	environments					269:280	built environments	263:280	built environments	263:280	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
35913000	6	81	theme	Oribacterium	1532:1543	arg1	abundance					1473:1481	greater abundance	1465:1481	greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter	1465:1561	The composition of the GM was significantly dissimilar between diets, with greater abundance of Erysipelatoclostridiaceae, Sanguibacteraceae, Oribacterium, and Sanguibacter and decreased circulating LPS in the urban-fed birds.					
35913000	3	82	from	GM	757:758	arg1	Zenaida					922:928	Zenaida	922:928	Zenaida	922:928	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	82	from	GM	757:758	arg1	doves					915:919	urban-caught mourning doves	893:919	urban-caught mourning doves (Zenaida macroura)	893:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	5	83	theme	intestine	1208:1216	arg1	contents					1186:1193	contents	1186:1193	contents of the large intestine	1186:1216	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	2	84	theme	metabolic	398:406	arg1	profiles					408:415	metabolic profiles	398:415	metabolic profiles of host physiological systems	398:445	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	3	85	theme	tissues	830:836	arg1	GM					757:758	the GM	753:758	the GM	753:758	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	85	theme	tissues	830:836	arg1	profiles					775:782	the metabolic profiles	761:782	the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin	761:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	85	theme	tissues	830:836	arg1	factors					882:888	inflammatory factors	869:888	inflammatory factors in urban-caught mourning doves (Zenaida macroura)	869:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	2	86	theme	overall	452:458	arg1	knowledge					460:468	our overall knowledge	448:468	our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host	448:548	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	3	87	theme	inflammatory	869:880	arg1	factors					882:888	inflammatory factors	869:888	inflammatory factors in urban-caught mourning doves (Zenaida macroura)	869:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	88	theme	investigation	629:641	arg1	objective					611:619	the objective	607:619	the objective of this investigation	607:641	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	89	theme	endotoxin	855:863	arg1	GM					757:758	the GM	753:758	the GM	753:758	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	89	theme	endotoxin	855:863	arg1	profiles					775:782	the metabolic profiles	761:782	the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin	761:863	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	89	theme	endotoxin	855:863	arg1	factors					882:888	inflammatory factors	869:888	inflammatory factors in urban-caught mourning doves (Zenaida macroura)	869:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	2	90	theme	nutritional	303:313	arg1	intakes					315:321	such nutritional intakes	298:321	such nutritional intakes	298:321	In relation to such nutritional intakes and their presumed impact on microbes harbored in the intestinal tract and metabolic profiles of host physiological systems, our overall knowledge of the role of gut microbiome (GM) and metabolomic expression in the avian host lags far behind our understanding of mammals.					
35913000	3	91	dep	Zenaida	922:928	arg1	macroura					930:937	Zenaida macroura	922:937	Zenaida macroura	922:937	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	92	theme	mourning	906:913	arg1	Zenaida					922:928	Zenaida	922:928	Zenaida	922:928	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	3	92	theme	mourning	906:913	arg1	doves					915:919	urban-caught mourning doves	893:919	urban-caught mourning doves (Zenaida macroura)	893:938	Therefore, the objective of this investigation was to examine the potential differential effect of an urban modeled versus control (i.e., bird seed) diet on the GM, the metabolic profiles of plasma, liver, adipose, kidney, and muscle tissues, and circulating endotoxin and inflammatory factors in urban-caught mourning doves (Zenaida macroura).					
35913000	5	93	theme	metabolomic	1260:1270	arg1	analyses					1272:1279	metabolomic analyses	1260:1279	metabolomic analyses	1260:1279	After a 4-wk-diet period, contents of the large intestine were sequenced to profile the microbiome, metabolomic analyses were performed on plasma and tissue homogenates, and circulating LPS and inflammatory markers were assessed.					
35913000	1	94	theme	human	228:232	arg1	refuse					234:239	human refuse	228:239	human refuse	228:239	Urbanization influences food quality and availability for many avian species, with increased access to human refuse and food subsidies in built environments.					
36972818	5	0	theme	low	983:985	arg1	content					991:997	low ash content	983:997	low ash content	983:997	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	6	1	theme	starch	1159:1164	arg1	samples					1166:1172	the starch samples	1155:1172	the starch samples	1155:1172	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	4	2	theme	weight	824:829	arg1	51.76 g/100 g					794:806	51.76 g/100 g	794:806	51.76 g/100 g of the corm dry weight	794:829	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	5	3	theme	amino	1036:1040	arg1	acid					1042:1045	free amino acid	1031:1045	free amino acid	1031:1045	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	0	4	theme	surface	89:95	arg1	RSM					110:112	RSM	110:112	RSM	110:112	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	4	theme	surface	89:95	arg1	methodology					97:107	response surface methodology	80:107	response surface methodology (RSM)	80:113	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	1	5	theme	interest	331:338	arg1	topic					322:326	a topic	320:326	a topic of interest	320:338	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36972818	2	6	theme	neural	549:554	arg1	ANN					565:567	ANN	565:567	ANN	565:567	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	6	theme	neural	549:554	arg1	network					556:562	artificial neural network	538:562	artificial neural network (ANN)	538:568	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	3	7	with	yield	640:644	arg1	precision					658:666	higher precision	651:666	higher precision	651:666	The RSM model performed better than the ANN in predicting the starch yield with higher precision.					
36972818	8	8	theme	starch	1471:1476	arg1	molecules					1478:1486	starch molecules	1471:1486	starch molecules irrespective of the variation in extraction parameters	1471:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	9	from	Optimization	0:11	arg1	corms					68:72	Amorphophallus paeoniifolius corms	39:72	Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN)	39:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	10	theme	chemical	184:191	arg1	attributes					193:202	tenable chemical attributes	176:202	tenable chemical attributes	176:202	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	4	11	theme	yield	765:769	arg1	improvement					743:753	the significant improvement	727:753	the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight)	727:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	2	12	theme	yam	447:449	arg1	corms					424:428	the corms	420:428	the corms of elephant foot yam (Amorphophallus paeoniifolius)	420:480	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	0	13	from	corms	68:72	arg1	Optimization					0:11	Optimization	0:11	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.	0:203	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	13	from	corms	68:72	arg1	extraction					23:32	starch extraction	16:32	starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN)	16:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	14	theme	tenable	176:182	arg1	attributes					193:202	tenable chemical attributes	176:202	tenable chemical attributes	176:202	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	8	15	theme	irrespective	1488:1499	arg1	molecules					1478:1486	starch molecules	1471:1486	starch molecules irrespective of the variation in extraction parameters	1471:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	1	16	theme	starch	265:270	arg1	yield					272:276	the starch yield	261:276	the starch yield from unconventional plants	261:303	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36972818	4	17	from	paeoniifolius	779:791	arg1	improvement					743:753	the significant improvement	727:753	the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight)	727:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	4	17	from	paeoniifolius	779:791	arg1	yield					765:769	starch yield	758:769	starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight)	758:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	7	18	theme	C-type	1227:1232	arg1	2θ = 14.303°					1242:1253	2θ = 14.303°	1242:1253	2θ = 14.303°	1242:1253	Moreover, the XRD analysis showed the prevalence of C-type starch (2θ = 14.303°).					
36972818	7	18	theme	C-type	1227:1232	arg1	starch					1234:1239	C-type starch	1227:1239	C-type starch (2θ = 14.303°)	1227:1254	Moreover, the XRD analysis showed the prevalence of C-type starch (2θ = 14.303°).					
36972818	4	19	theme	first	708:712	arg1	time					714:717	the first time	704:717	the first time	704:717	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	8	20	theme	attributes	1457:1466	arg1	sustentation					1430:1441	the sustentation	1426:1441	the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters	1426:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	6	21	dep	composition	1129:1139	arg1	the					1116:1118	the	1116:1118	the	1116:1118	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	3	22	theme	higher	651:656	arg1	precision					658:666	higher precision	651:666	higher precision	651:666	The RSM model performed better than the ANN in predicting the starch yield with higher precision.					
36972818	1	23	from	plants	298:303	arg1	yield					272:276	the starch yield	261:276	the starch yield from unconventional plants	261:303	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36972818	4	24	theme	corm	815:818	arg1	weight					824:829	the corm dry weight	811:829	the corm dry weight	811:829	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	4	25	dep	paeoniifolius	779:791	arg1	51.76 g/100 g					794:806	51.76 g/100 g	794:806	51.76 g/100 g of the corm dry weight	794:829	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	8	26	theme	similar	1383:1389	arg1	characteristics					1391:1405	more or less similar characteristics	1370:1405	more or less similar characteristics	1370:1405	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	4	27	theme	dry	820:822	arg1	weight					824:829	the corm dry weight	811:829	the corm dry weight	811:829	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	2	28	theme	present	362:368	arg1	work					370:373	the present work	358:373	the present work	358:373	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	29	from	corms	424:428	arg1	extraction					404:413	the starch extraction	393:413	the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN)	393:568	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	8	30	theme	less	1378:1381	arg1	characteristics					1391:1405	more or less similar characteristics	1370:1405	more or less similar characteristics	1370:1405	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	6	31	theme	FTIR	1087:1090	arg1	analysis					1092:1099	The FTIR analysis	1083:1099	The FTIR analysis	1083:1099	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	8	32	theme	physicochemical	1272:1286	arg1	properties					1326:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	33	theme	extraction	23:32	arg1	Optimization					0:11	Optimization	0:11	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.	0:203	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	8	34	theme	other	1266:1270	arg1	properties					1326:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	35	theme	neural	130:135	arg1	network					137:143	artificial neural network	119:143	artificial neural network (ANN)	119:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	35	theme	neural	130:135	arg1	ANN					146:148	ANN	146:148	ANN	146:148	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	7	36	theme	starch	1234:1239	arg1	prevalence					1213:1222	the prevalence	1209:1222	the prevalence of C-type starch (2θ = 14.303°)	1209:1254	Moreover, the XRD analysis showed the prevalence of C-type starch (2θ = 14.303°).					
36972818	2	37	theme	starch	397:402	arg1	extraction					404:413	the starch extraction	393:413	the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN)	393:568	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	0	38	theme	starch	16:21	arg1	extraction					23:32	starch extraction	16:32	starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN)	16:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	1	39	theme	unconventional	283:296	arg1	plants					298:303	unconventional plants	283:303	unconventional plants	283:303	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36972818	0	40	theme	artificial	119:128	arg1	network					137:143	artificial neural network	119:143	artificial neural network (ANN)	119:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	40	theme	artificial	119:128	arg1	ANN					146:148	ANN	146:148	ANN	146:148	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	8	41	theme	more	1370:1373	arg1	characteristics					1391:1405	more or less similar characteristics	1370:1405	more or less similar characteristics	1370:1405	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	42	theme	Amorphophallus	39:52	arg1	corms					68:72	Amorphophallus paeoniifolius corms	39:72	Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN)	39:149	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	5	43	theme	free	1031:1034	arg1	acid					1042:1045	free amino acid	1031:1045	free amino acid	1031:1045	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	2	44	theme	surface	508:514	arg1	methodology					516:526	response surface methodology	499:526	response surface methodology (RSM)	499:532	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	44	theme	surface	508:514	arg1	RSM					529:531	RSM	529:531	RSM	529:531	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	5	45	theme	variable	934:941	arg1	7.17-14.14 μm					957:969	7.17-14.14 μm	957:969	7.17-14.14 μm	957:969	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	5	45	theme	variable	934:941	arg1	size					951:954	a variable granule size	932:954	a variable granule size (7.17-14.14 μm)	932:970	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	8	46	theme	molecules	1478:1486	arg1	attributes					1457:1466	beneficial attributes	1446:1466	beneficial attributes of starch molecules irrespective of the variation in extraction parameters	1446:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	8	47	from	variation	1508:1516	arg1	parameters					1532:1541	extraction parameters	1521:1541	extraction parameters	1521:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	2	48	theme	foot	442:445	arg1	yam					447:449	elephant foot yam	433:449	elephant foot yam (Amorphophallus paeoniifolius)	433:480	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	49	theme	response	499:506	arg1	methodology					516:526	response surface methodology	499:526	response surface methodology (RSM)	499:532	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	49	theme	response	499:506	arg1	RSM					529:531	RSM	529:531	RSM	529:531	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	5	50	theme	granule	943:949	arg1	7.17-14.14 μm					957:969	7.17-14.14 μm	957:969	7.17-14.14 μm	957:969	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	5	50	theme	granule	943:949	arg1	size					951:954	a variable granule size	932:954	a variable granule size (7.17-14.14 μm)	932:970	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	5	51	theme	extracted	837:845	arg1	samples					854:860	The extracted starch samples	833:860	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS)	833:920	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	2	52	theme	elephant	433:440	arg1	yam					447:449	elephant foot yam	433:449	elephant foot yam (Amorphophallus paeoniifolius)	433:480	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	5	53	theme	moisture	1000:1007	arg1	content					1009:1015	moisture content	1000:1015	moisture content	1000:1015	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	2	54	theme	artificial	538:547	arg1	ANN					565:567	ANN	565:567	ANN	565:567	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	2	54	theme	artificial	538:547	arg1	network					556:562	artificial neural network	538:562	artificial neural network (ANN)	538:568	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	8	55	theme	biochemical	1289:1299	arg1	properties					1326:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	56	dep	Amorphophallus	39:52	arg1	paeoniifolius					54:66	paeoniifolius	54:66	paeoniifolius	54:66	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	2	57	with	extraction	404:413	arg1	the					487:489	the	487:489	the	487:489	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	5	58	theme	ash	987:989	arg1	content					991:997	low ash content	983:997	low ash content	983:997	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	3	59	theme	starch	633:638	arg1	yield					640:644	the starch yield	629:644	the starch yield with higher precision	629:666	The RSM model performed better than the ANN in predicting the starch yield with higher precision.					
36972818	2	60	dep	the	487:489	arg1	help					491:494	help	491:494	help	491:494	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	4	61	theme	starch	758:763	arg1	yield					765:769	starch yield	758:769	starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight)	758:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	2	62	dep	yam	447:449	arg1	paeoniifolius					467:479	Amorphophallus paeoniifolius	452:479	Amorphophallus paeoniifolius	452:479	In this respect, the present work aimed to optimize the starch extraction from the corms of elephant foot yam (Amorphophallus paeoniifolius) with the help of response surface methodology (RSM) and artificial neural network (ANN).					
36972818	8	63	theme	variation	1508:1516	arg1	irrespective					1488:1499	irrespective	1488:1499	irrespective	1488:1499	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	8	64	theme	functional	1302:1311	arg1	properties					1326:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	4	65	from	improvement	743:753	arg1	paeoniifolius					779:791	A. paeoniifolius	776:791	A. paeoniifolius (51.76 g/100 g of the corm dry weight)	776:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	5	66	theme	starch	847:852	arg1	samples					854:860	The extracted starch samples	833:860	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS)	833:920	The extracted starch samples based on yield - high (APHS), medium (APMS), and low (APLS) exhibited a variable granule size (7.17-14.14 μm) along with low ash content, moisture content, protein, and free amino acid indicating purity and desirability.					
36972818	6	67	theme	samples	1166:1172	arg1	purity					1145:1150	purity	1145:1150	purity	1145:1150	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	6	67	theme	samples	1166:1172	arg1	composition					1129:1139	chemical composition	1120:1139	chemical composition	1120:1139	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	8	68	theme	starch	1348:1353	arg1	samples					1355:1361	the three starch samples	1338:1361	the three starch samples	1338:1361	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	8	69	theme	pasting	1318:1324	arg1	properties					1326:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	other physicochemical, biochemical, functional, and pasting properties	1266:1335	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	3	70	theme	RSM	575:577	arg1	model					579:583	The RSM model	571:583	The RSM model	571:583	The RSM model performed better than the ANN in predicting the starch yield with higher precision.					
36972818	8	71	theme	extraction	1521:1530	arg1	parameters					1532:1541	extraction parameters	1521:1541	extraction parameters	1521:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	0	72	theme	response	80:87	arg1	RSM					110:112	RSM	110:112	RSM	110:112	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	0	72	theme	response	80:87	arg1	methodology					97:107	response surface methodology	80:107	response surface methodology (RSM)	80:113	Optimization of starch extraction from Amorphophallus paeoniifolius corms using response surface methodology (RSM) and artificial neural network (ANN) for improving yield with tenable chemical attributes.					
36972818	4	73	theme	significant	731:741	arg1	improvement					743:753	the significant improvement	727:753	the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight)	727:830	In this connection, this study for the first time reports the significant improvement of starch yield from A. paeoniifolius (51.76 g/100 g of the corm dry weight).					
36972818	1	74	theme	extraction	228:237	arg1	process					239:245	the extraction process	224:245	the extraction process for improving the starch yield from unconventional plants	224:303	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36972818	7	75	theme	XRD	1189:1191	arg1	analysis					1193:1200	the XRD analysis	1185:1200	the XRD analysis	1185:1200	Moreover, the XRD analysis showed the prevalence of C-type starch (2θ = 14.303°).					
36972818	8	76	theme	beneficial	1446:1455	arg1	attributes					1457:1466	beneficial attributes	1446:1466	beneficial attributes of starch molecules irrespective of the variation in extraction parameters	1446:1541	Based on other physicochemical, biochemical, functional, and pasting properties, the three starch samples showed more or less similar characteristics thereby indicating the sustentation of beneficial attributes of starch molecules irrespective of the variation in extraction parameters.					
36972818	6	77	theme	chemical	1120:1127	arg1	composition					1129:1139	chemical composition	1120:1139	chemical composition	1120:1139	The FTIR analysis also confirmed the chemical composition and purity of the starch samples.					
36972818	1	78	theme	process	239:245	arg1	development					209:219	The development	205:219	The development of the extraction process for improving the starch yield from unconventional plants	205:303	The development of the extraction process for improving the starch yield from unconventional plants is emerging as a topic of interest.					
36105645	6	0	theme	sweet	921:925	arg1	chromosomes					934:944	five sweet orange chromosomes	916:944	five sweet orange chromosomes	916:944	Results Here, eight TPS genes were identified and were found to be randomly distributed in five sweet orange chromosomes.					
36105645	4	1	theme	gene	570:573	arg1	family					575:580	The TPS gene family	562:580	Methods The TPS gene family	554:580	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	8	2	theme	intron	1165:1170	arg1	structures					1172:1181	conserved intron structures	1155:1181	conserved intron structures	1155:1181	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	3	3	theme	sweet	540:544	arg1	orange					546:551	sweet orange	540:551	sweet orange	540:551	At present, little information is available about the TPS gene family in sweet orange.					
36105645	9	4	theme	cis-acting	1211:1220	arg1	elements					1222:1229	The cis-acting elements	1207:1229	The cis-acting elements of CisTPS genes	1207:1245	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	8	5	contain	had	1151:1153	arg2	structures					1172:1181	conserved intron structures	1155:1181	conserved intron structures	1155:1181	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	8	5	contain	had	1151:1153	arg2	compositions					1193:1204	motif compositions	1187:1204	motif compositions	1187:1204	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	8	5	contain	had	1151:1153	arg1	genes					1127:1131	genes	1127:1131	genes in each subfamily	1127:1149	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	1	6	theme	Trehalose-6-phosphate	197:217	arg1	enzyme					250:255	an essential enzyme	237:255	an essential enzyme for synthesizing trehalose	237:282	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	6	theme	Trehalose-6-phosphate	197:217	arg1	TPS					229:231	TPS	229:231	TPS	229:231	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	6	theme	Trehalose-6-phosphate	197:217	arg1	synthase					219:226	Background Trehalose-6-phosphate synthase	186:226	Background Trehalose-6-phosphate synthase (TPS)	186:232	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	12	7	theme	gene	1752:1755	arg1	family					1757:1762	this gene family	1747:1762	this gene family	1747:1762	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	0	8	theme	expression	115:124	arg1	analysis					126:133	expression analysis	115:133	expression analysis in response to phytohormones and abiotic stresses	115:183	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	9	9	theme	genes	1241:1245	arg1	elements					1222:1229	The cis-acting elements	1207:1229	The cis-acting elements of CisTPS genes	1207:1245	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	0	10	from	orange	86:91	arg1	identification					12:25	Genome-wide identification	0:25	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	0:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	10	from	orange	86:91	arg1	analysis					126:133	expression analysis	115:133	expression analysis in response to phytohormones and abiotic stresses	115:183	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	12	11	from	reference	1733:1741	arg1	plants					1773:1778	other plants	1767:1778	other plants	1767:1778	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	7	12	theme	CisTPS	1024:1029	arg1	proteins					1031:1038	all CisTPS proteins	1020:1038	all CisTPS proteins	1020:1038	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	0	13	theme	abiotic	168:174	arg1	stresses					176:183	abiotic stresses	168:183	abiotic stresses	168:183	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	5	14	theme	genes	690:694	arg1	expression					669:678	the expression	665:678	the expression of CisTPS genes	665:694	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	15	theme	reverse-transcriptase	766:786	arg1	qRT-PCR					815:821	qRT-PCR	815:821	qRT-PCR	815:821	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	15	theme	reverse-transcriptase	766:786	arg1	reaction					805:812	quantitative reverse-transcriptase polymerase chain reaction	753:812	quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR)	753:822	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	1	16	theme	stress	340:345	arg1	response					347:354	stress response	340:354	stress response	340:354	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	9	17	from	roles	1263:1267	arg1	phytohormone					1272:1283	phytohormone	1272:1283	phytohormone	1272:1283	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	9	17	from	roles	1263:1267	arg1	responses					1296:1304	stress responses	1289:1304	stress responses	1289:1304	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	3	18	from	family	530:535	arg1	orange					546:551	sweet orange	540:551	sweet orange	540:551	At present, little information is available about the TPS gene family in sweet orange.					
36105645	5	19	theme	chain	799:803	arg1	qRT-PCR					815:821	qRT-PCR	815:821	qRT-PCR	815:821	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	19	theme	chain	799:803	arg1	reaction					805:812	quantitative reverse-transcriptase polymerase chain reaction	753:812	quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR)	753:822	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	0	20	theme	Citrus	94:99	arg1	orange					86:91	sweet orange	80:91	sweet orange (Citrus sinensis)	80:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	20	theme	Citrus	94:99	arg1	sinensis					101:108	Citrus sinensis	94:108	Citrus sinensis	94:108	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	8	21	theme	phylogenetic	1045:1056	arg1	tree					1058:1061	The phylogenetic tree	1041:1061	The phylogenetic tree	1041:1061	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	7	22	theme	trehalose-6-phosphate	955:975	arg1	phosphatase					977:987	trehalose-6-phosphate phosphatase	955:987	trehalose-6-phosphate phosphatase (TPP)	955:993	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	7	22	theme	trehalose-6-phosphate	955:975	arg1	TPP					990:992	TPP	990:992	TPP	990:992	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	12	23	theme	trehalose	1671:1679	arg1	regulation					1681:1690	trehalose regulation	1671:1690	trehalose regulation in sweet orange	1671:1706	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	7	24	theme	TPS	947:949	arg1	domains					995:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	2	25	theme	transgenic	446:455	arg1	material					457:464	a common transgenic material	437:464	a common transgenic material	437:464	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	0	26	theme	sweet	80:84	arg1	orange					86:91	sweet orange	80:91	sweet orange (Citrus sinensis)	80:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	26	theme	sweet	80:84	arg1	sinensis					101:108	Citrus sinensis	94:108	Citrus sinensis	94:108	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	11	27	theme	Expression	1429:1438	arg1	profiles					1440:1447	Expression profiles	1429:1447	Expression profiles	1429:1447	Expression profiles showed that CisTPS genes exhibited tissue specificity and were differentially expressed in response to phytohormones and abiotic stresses.					
36105645	0	28	theme	Genome-wide	0:10	arg1	identification					12:25	Genome-wide identification	0:25	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	0:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	8	29	theme	CisTPS	1075:1080	arg1	genes					1082:1086	CisTPS genes	1075:1086	CisTPS genes	1075:1086	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	12	30	theme	TPS	1652:1654	arg1	family					1661:1666	the TPS gene family	1648:1666	the TPS gene family	1648:1666	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	1	31	theme	significant	293:303	arg1	regulator					305:313	a significant regulator	291:313	a significant regulator of plant development and stress response	291:354	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	12	32	from	functions	1635:1643	arg1	regulation					1681:1690	trehalose regulation	1671:1690	trehalose regulation in sweet orange	1671:1706	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	12	33	theme	family	1661:1666	arg1	functions					1635:1643	the functions	1631:1643	the functions of the TPS gene family in trehalose regulation in sweet orange	1631:1706	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	11	34	theme	CisTPS	1461:1466	arg1	genes					1468:1472	CisTPS genes	1461:1472	CisTPS genes	1461:1472	Expression profiles showed that CisTPS genes exhibited tissue specificity and were differentially expressed in response to phytohormones and abiotic stresses.					
36105645	2	35	theme	fruit	417:421	arg1	orange					363:368	Sweet orange	357:368	Sweet orange (Citrus sinensis)	357:386	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	35	theme	fruit	417:421	arg1	crop					428:431	an economically important fruit tree crop	391:431	an economically important fruit tree crop	391:431	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	0	36	theme	trehalose-6-phosphate	34:54	arg1	family					70:75	the trehalose-6-phosphate synthase gene family	30:75	the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	30:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	2	37	theme	Sweet	357:361	arg1	crop					428:431	an economically important fruit tree crop	391:431	an economically important fruit tree crop	391:431	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	37	theme	Sweet	357:361	arg1	orange					363:368	Sweet orange	357:368	Sweet orange (Citrus sinensis)	357:386	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	37	theme	Sweet	357:361	arg1	sinensis					378:385	Citrus sinensis	371:385	Citrus sinensis	371:385	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	0	38	theme	gene	65:68	arg1	family					70:75	the trehalose-6-phosphate synthase gene family	30:75	the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	30:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	1	39	theme	development	324:334	arg1	regulator					305:313	a significant regulator	291:313	a significant regulator of plant development and stress response	291:354	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	39	theme	development	324:334	arg1	enzyme					250:255	an essential enzyme	237:255	an essential enzyme for synthesizing trehalose	237:282	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	39	theme	development	324:334	arg1	synthase					219:226	Background Trehalose-6-phosphate synthase	186:226	Background Trehalose-6-phosphate synthase (TPS)	186:232	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	3	40	from	present	470:476	arg1	available					501:509	available	501:509	available	501:509	At present, little information is available about the TPS gene family in sweet orange.					
36105645	6	41	theme	TPS	845:847	arg1	genes					849:853	eight TPS genes	839:853	eight TPS genes	839:853	Results Here, eight TPS genes were identified and were found to be randomly distributed in five sweet orange chromosomes.					
36105645	7	42	located	observed	1008:1015	arg2	domains					995:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	7	42	located	observed	1008:1015	arg1	proteins					1031:1038	all CisTPS proteins	1020:1038	all CisTPS proteins	1020:1038	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	1	43	theme	essential	240:248	arg1	enzyme					250:255	an essential enzyme	237:255	an essential enzyme for synthesizing trehalose	237:282	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	43	theme	essential	240:248	arg1	synthase					219:226	Background Trehalose-6-phosphate synthase	186:226	Background Trehalose-6-phosphate synthase (TPS)	186:232	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	6	44	theme	orange	927:932	arg1	chromosomes					934:944	five sweet orange chromosomes	916:944	five sweet orange chromosomes	916:944	Results Here, eight TPS genes were identified and were found to be randomly distributed in five sweet orange chromosomes.					
36105645	4	45	theme	sweet	603:607	arg1	orange					609:614	sweet orange	603:614	sweet orange genome	603:621	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	12	46	theme	other	1767:1771	arg1	plants					1773:1778	other plants	1767:1778	other plants	1767:1778	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	4	47	theme	TPS	566:568	arg1	family					575:580	The TPS gene family	562:580	Methods The TPS gene family	554:580	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	11	48	theme	abiotic	1570:1576	arg1	stresses					1578:1585	abiotic stresses	1570:1585	abiotic stresses	1570:1585	Expression profiles showed that CisTPS genes exhibited tissue specificity and were differentially expressed in response to phytohormones and abiotic stresses.					
36105645	8	49	theme	conserved	1155:1163	arg1	structures					1172:1181	conserved intron structures	1155:1181	conserved intron structures	1155:1181	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	12	50	from	regulation	1681:1690	arg1	orange					1701:1706	sweet orange	1695:1706	sweet orange	1695:1706	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	3	51	theme	gene	525:528	arg1	family					530:535	the TPS gene family	517:535	the TPS gene family in sweet orange	517:551	At present, little information is available about the TPS gene family in sweet orange.					
36105645	1	52	theme	Background	186:195	arg1	enzyme					250:255	an essential enzyme	237:255	an essential enzyme for synthesizing trehalose	237:282	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	52	theme	Background	186:195	arg1	TPS					229:231	TPS	229:231	TPS	229:231	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	52	theme	Background	186:195	arg1	synthase					219:226	Background Trehalose-6-phosphate synthase	186:226	Background Trehalose-6-phosphate synthase (TPS)	186:232	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	8	53	theme	motif	1187:1191	arg1	compositions					1193:1204	motif compositions	1187:1204	motif compositions	1187:1204	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	6	54	dep	Results	825:831	arg1	identified					860:869	identified	860:869	were identified	855:869	Results Here, eight TPS genes were identified and were found to be randomly distributed in five sweet orange chromosomes.					
36105645	6	54	dep	Results	825:831	arg1	found					880:884	found	880:884	were found to be randomly distributed in five sweet orange chromosomes	875:944	Results Here, eight TPS genes were identified and were found to be randomly distributed in five sweet orange chromosomes.					
36105645	9	55	theme	CisTPS	1234:1239	arg1	genes					1241:1245	CisTPS genes	1234:1245	CisTPS genes	1234:1245	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	4	56	theme	bioinformatics	626:639	arg1	analysis					641:648	bioinformatics analysis	626:648	bioinformatics analysis	626:648	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	5	57	theme	CisTPS	683:688	arg1	genes					690:694	CisTPS genes	683:694	CisTPS genes	683:694	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	0	58	dep	phytohormones	150:162	arg1	response					138:145	response	138:145	response	138:145	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	11	59	theme	tissue	1484:1489	arg1	specificity					1491:1501	tissue specificity	1484:1501	tissue specificity	1484:1501	Expression profiles showed that CisTPS genes exhibited tissue specificity and were differentially expressed in response to phytohormones and abiotic stresses.					
36105645	5	60	theme	quantitative	753:764	arg1	qRT-PCR					815:821	qRT-PCR	815:821	qRT-PCR	815:821	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	60	theme	quantitative	753:764	arg1	reaction					805:812	quantitative reverse-transcriptase polymerase chain reaction	753:812	quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR)	753:822	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	9	61	theme	stress	1289:1294	arg1	responses					1296:1304	stress responses	1289:1304	stress responses	1289:1304	The cis-acting elements of CisTPS genes suggested their roles in phytohormone and stress responses.					
36105645	12	62	theme	valuable	1724:1731	arg1	reference					1733:1741	a valuable reference	1722:1741	a valuable reference for this gene family in other plants	1722:1778	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	5	63	theme	abiotic	733:739	arg1	stresses					741:748	abiotic stresses	733:748	abiotic stresses	733:748	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	64	theme	polymerase	788:797	arg1	qRT-PCR					815:821	qRT-PCR	815:821	qRT-PCR	815:821	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	5	64	theme	polymerase	788:797	arg1	reaction					805:812	quantitative reverse-transcriptase polymerase chain reaction	753:812	quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR)	753:822	Additionally, the expression of CisTPS genes was analyzed under phytohormones and abiotic stresses by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).					
36105645	1	65	theme	response	347:354	arg1	regulator					305:313	a significant regulator	291:313	a significant regulator of plant development and stress response	291:354	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	65	theme	response	347:354	arg1	enzyme					250:255	an essential enzyme	237:255	an essential enzyme for synthesizing trehalose	237:282	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	1	65	theme	response	347:354	arg1	synthase					219:226	Background Trehalose-6-phosphate synthase	186:226	Background Trehalose-6-phosphate synthase (TPS)	186:232	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	12	66	theme	sweet	1695:1699	arg1	orange					1701:1706	sweet orange	1695:1706	sweet orange	1695:1706	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	8	67	from	genes	1127:1131	arg1	subfamily					1141:1149	each subfamily	1136:1149	each subfamily	1136:1149	The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions.					
36105645	0	68	from	identification	12:25	arg1	orange					86:91	sweet orange	80:91	sweet orange (Citrus sinensis)	80:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	68	from	identification	12:25	arg1	sinensis					101:108	Citrus sinensis	94:108	Citrus sinensis	94:108	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	69	from	family	70:75	arg1	orange					86:91	sweet orange	80:91	sweet orange (Citrus sinensis)	80:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	69	from	family	70:75	arg1	sinensis					101:108	Citrus sinensis	94:108	Citrus sinensis	94:108	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	10	70	theme	CisTPS	1311:1316	arg1	genes					1318:1322	All CisTPS genes	1307:1322	All CisTPS genes	1307:1322	All CisTPS genes were ubiquitously expressed in roots, leaves, and stems, and six members were highly expressed in roots.					
36105645	4	71	dep	Methods	554:560	arg1	family					575:580	The TPS gene family	562:580	Methods The TPS gene family	554:580	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	7	72	theme	phosphatase	977:987	arg1	domains					995:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains	947:1001	TPS and trehalose-6-phosphate phosphatase (TPP) domains were observed in all CisTPS proteins.					
36105645	2	73	theme	common	439:444	arg1	material					457:464	a common transgenic material	437:464	a common transgenic material	437:464	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	74	theme	tree	423:426	arg1	orange					363:368	Sweet orange	357:368	Sweet orange (Citrus sinensis)	357:386	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	74	theme	tree	423:426	arg1	crop					428:431	an economically important fruit tree crop	391:431	an economically important fruit tree crop	391:431	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	0	75	theme	synthase	56:63	arg1	family					70:75	the trehalose-6-phosphate synthase gene family	30:75	the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	30:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	12	76	theme	gene	1656:1659	arg1	family					1661:1666	the TPS gene family	1648:1666	the TPS gene family	1648:1666	This study lays a foundation for revealing the functions of the TPS gene family in trehalose regulation in sweet orange, and provides a valuable reference for this gene family in other plants.					
36105645	4	77	theme	orange	609:614	arg1	genome					616:621	sweet orange genome	603:621	sweet orange genome	603:621	Methods The TPS gene family were identified from sweet orange genome by bioinformatics analysis.					
36105645	2	78	theme	important	407:415	arg1	orange					363:368	Sweet orange	357:368	Sweet orange (Citrus sinensis)	357:386	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	78	theme	important	407:415	arg1	crop					428:431	an economically important fruit tree crop	391:431	an economically important fruit tree crop	391:431	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	0	79	theme	family	70:75	arg1	identification					12:25	Genome-wide identification	0:25	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis)	0:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	79	theme	family	70:75	arg1	analysis					126:133	expression analysis	115:133	expression analysis in response to phytohormones and abiotic stresses	115:183	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	1	80	theme	plant	318:322	arg1	development					324:334	plant development	318:334	plant development	318:334	Background Trehalose-6-phosphate synthase (TPS) is an essential enzyme for synthesizing trehalose and is a significant regulator of plant development and stress response.					
36105645	2	81	theme	Citrus	371:376	arg1	orange					363:368	Sweet orange	357:368	Sweet orange (Citrus sinensis)	357:386	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	2	81	theme	Citrus	371:376	arg1	sinensis					378:385	Citrus sinensis	371:385	Citrus sinensis	371:385	Sweet orange (Citrus sinensis) is an economically important fruit tree crop and a common transgenic material.					
36105645	11	82	dep	phytohormones	1552:1564	arg1	response					1540:1547	response	1540:1547	response	1540:1547	Expression profiles showed that CisTPS genes exhibited tissue specificity and were differentially expressed in response to phytohormones and abiotic stresses.					
36105645	3	83	theme	little	479:484	arg1	information					486:496	little information	479:496	little information	479:496	At present, little information is available about the TPS gene family in sweet orange.					
36105645	0	84	from	analysis	126:133	arg1	orange					86:91	sweet orange	80:91	sweet orange (Citrus sinensis)	80:109	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	0	84	from	analysis	126:133	arg1	sinensis					101:108	Citrus sinensis	94:108	Citrus sinensis	94:108	Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stresses.					
36105645	3	85	theme	TPS	521:523	arg1	family					530:535	the TPS gene family	517:535	the TPS gene family in sweet orange	517:551	At present, little information is available about the TPS gene family in sweet orange.					
35296350	13	0	dep	CONCLUSIONS	1977:1987	arg1	CONCLUSIONS					1977:1987	CONCLUSIONS Surface chemistry and size	1977:2014	CONCLUSIONS Surface chemistry and size	1977:2014	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	13	0	dep	CONCLUSIONS	1977:1987	arg1	size					2011:2014	size	2011:2014	size	2011:2014	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	13	0	dep	CONCLUSIONS	1977:1987	arg1	chemistry					1997:2005	Surface chemistry	1989:2005	Surface chemistry	1989:2005	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	10	1	theme	remarkable	1458:1467	arg1	effects					1479:1485	No remarkable cytotoxic effects	1455:1485	No remarkable cytotoxic effects	1455:1485	No remarkable cytotoxic effects were induced by any of the cellulosic materials.					
35296350	2	2	theme	toxicity	345:352	arg1	assessment					354:363	a thorough toxicity assessment	334:363	a thorough toxicity assessment	334:363	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	13	3	theme	in	2029:2030	arg1	formation					2056:2064	the in vitro intracellular ROS formation	2025:2064	the in vitro intracellular ROS formation	2025:2064	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	12	4	theme	chromosome	1874:1883	arg1	damage					1885:1890	chromosome damage	1874:1890	chromosome damage	1874:1890	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	7	5	from	homogenous	1204:1213	arg1	agreement					1219:1227	agreement	1219:1227	agreement with its high surface group density	1219:1263	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	13	6	theme	intracellular	2038:2050	arg1	formation					2056:2064	the in vitro intracellular ROS formation	2025:2064	the in vitro intracellular ROS formation	2025:2064	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	4	7	theme	size	656:659	arg1	fractions					661:669	three size fractions	650:669	three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	650:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	3	8	theme	surface	524:530	arg1	composition					532:542	surface composition	524:542	surface composition	524:542	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	12	9	theme	C-CNF	1852:1856	arg1	fraction					1840:1847	the coarse fraction	1829:1847	the coarse fraction of C-CNF, which produced chromosome damage,	1829:1891	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	12	9	theme	C-CNF	1852:1856	arg1	fraction					1691:1698	The fine fraction	1682:1698	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay),	1682:1823	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	6	10	theme	individual	1116:1125	arg1	nanofibrils					1127:1137	individual nanofibrils	1116:1137	individual nanofibrils	1116:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	6	11	from	presence	1013:1020	arg1	samples					1078:1084	the functionalized CNF samples	1055:1084	the functionalized CNF samples	1055:1084	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	15	12	theme	toxic	2463:2467	arg1	effects					2469:2475	their toxic effects	2457:2475	their toxic effects	2457:2475	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	8	13	theme	CNF	1310:1312	arg1	samples					1314:1320	all the CNF samples	1302:1320	all the CNF samples	1302:1320	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	0	14	theme	nanofibrils	120:130	arg1	effects					99:105	genotoxic effects	89:105	genotoxic effects of cellulose nanofibrils	89:130	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	0	14	theme	nanofibrils	120:130	arg1	formation					48:56	the formation	44:56	the formation of reactive oxygen species	44:83	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	2	15	theme	high	297:300	arg1	biopersistence					302:315	high biopersistence	297:315	high biopersistence	297:315	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	14	16	theme	fine	2146:2149	arg1	cationic					2136:2143	cationic	2136:2143	cationic	2136:2143	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	14	16	theme	fine	2146:2149	arg1	E-CNF					2151:2155	fine E-CNF	2146:2155	fine E-CNF	2146:2155	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	1	17	theme	friendly	223:230	arg1	option					232:237	a sustainable and environmentally friendly option	189:237	a sustainable and environmentally friendly option for a broad range of applications	189:271	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	15	18	theme	CNFs	2330:2333	arg1	types					2321:2325	all types	2317:2325	all types of CNFs	2317:2333	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	12	19	theme	size	1961:1964	arg1	fractions					1966:1974	their respective size fractions	1944:1974	their respective size fractions	1944:1974	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	3	20	theme	BEAS-2B	623:629	arg1	cells					631:635	human bronchial epithelial BEAS-2B cells	596:635	human bronchial epithelial BEAS-2B cells	596:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	1	21	theme	Cellulose	144:152	arg1	CNFs					167:170	CNFs	167:170	CNFs	167:170	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	1	21	theme	Cellulose	144:152	arg1	nanofibrils					154:164	BACKGROUND Cellulose nanofibrils	133:164	BACKGROUND Cellulose nanofibrils (CNFs)	133:171	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	13	22	dep	in	2029:2030	arg1	vitro					2032:2036	vitro	2032:2036	vitro	2032:2036	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	0	23	theme	reactive	61:68	arg1	species					77:83	reactive oxygen species	61:83	reactive oxygen species	61:83	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	3	24	theme	bronchial	602:610	arg1	cells					631:635	human bronchial epithelial BEAS-2B cells	596:635	human bronchial epithelial BEAS-2B cells	596:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	12	25	from	induction	1924:1932	arg1	fractions					1966:1974	their respective size fractions	1944:1974	their respective size fractions	1944:1974	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	9	26	theme	cells	1448:1452	arg1	minority					1428:1435	a minority	1426:1435	a minority of BEAS-2B cells	1426:1452	CNF was internalized by a minority of BEAS-2B cells.					
35296350	8	27	theme	colloidal	1279:1287	arg1	stability					1289:1297	the colloidal stability	1275:1297	the colloidal stability of all the CNF samples	1275:1320	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	14	28	theme	coarse	2175:2180	arg1	anionic					2166:2172	anionic	2166:2172	anionic	2166:2172	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	14	28	theme	coarse	2175:2180	arg1	C-CNF					2182:2186	coarse C-CNF	2175:2186	coarse C-CNF	2175:2186	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	4	29	with	functionalized	767:780	arg1	EPTMAC					906:911	EPTMAC	906:911	EPTMAC	906:911	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	T-CNF					833:837	T-CNF	833:837	T-CNF	833:837	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	2,2,6,6-tetramethyl-piperidin-1-oxyl					787:822	2,2,6,6-tetramethyl-piperidin-1-oxyl	787:822	2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF)	787:838	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	E-CNF					915:919	E-CNF	915:919	E-CNF	915:919	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	chloride					896:903	epoxypropyltrimethylammonium chloride	867:903	epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	867:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	TEMPO					825:829	TEMPO	825:829	TEMPO	825:829	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	carboxymethyl					841:853	carboxymethyl	841:853	carboxymethyl (C-CNF)	841:861	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	29	with	functionalized	767:780	arg1	C-CNF					856:860	C-CNF	856:860	C-CNF	856:860	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	0	30	theme	species	77:83	arg1	effects					99:105	genotoxic effects	89:105	genotoxic effects of cellulose nanofibrils	89:130	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	0	30	theme	species	77:83	arg1	formation					48:56	the formation	44:56	the formation of reactive oxygen species	44:83	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	12	31	theme	micronucleus	1804:1815	arg1	assay					1817:1821	the micronucleus assay	1800:1821	the micronucleus assay	1800:1821	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	6	32	dep	RESULTS	1001:1007	arg1	compared					1160:1167	compared	1160:1167	compared with the U-CNF	1160:1182	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	6	32	dep	RESULTS	1001:1007	arg1	resulted					1086:1093	resulted	1086:1093	resulted in higher amounts of individual nanofibrils	1086:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	0	33	theme	genotoxic	89:97	arg1	effects					99:105	genotoxic effects	89:105	genotoxic effects of cellulose nanofibrils	89:130	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	15	34	theme	dispersion	2369:2378	arg1	method					2380:2385	the dispersion method	2365:2385	the dispersion method	2365:2385	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	15	34	theme	dispersion	2369:2378	arg1	conclusions					2280:2290	the conclusions	2276:2290	the conclusions	2276:2290	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	6	35	theme	surface	1029:1035	arg1	groups					1045:1050	the surface charged groups	1025:1050	the surface charged groups	1025:1050	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	8	36	theme	samples	1314:1320	arg1	stability					1289:1297	the colloidal stability	1275:1297	the colloidal stability of all the CNF samples	1275:1320	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	0	37	theme	Surface	0:6	arg1	functionalization					8:24	Surface functionalization	0:24	Surface functionalization	0:24	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	15	38	theme	synthesis	2343:2351	arg1	process					2353:2359	the synthesis process	2339:2359	the synthesis process	2339:2359	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	15	38	theme	synthesis	2343:2351	arg1	conclusions					2280:2290	the conclusions	2276:2290	the conclusions	2276:2290	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	4	39	theme	surface	725:731	arg1	chemistry					733:741	different surface chemistry	715:741	different surface chemistry	715:741	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	2	40	theme	toxic	475:479	arg1	response					481:488	the potential toxic response	461:488	the potential toxic response to CNF	461:495	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	4	41	with	fractions	661:669	arg1	chemistry					733:741	different surface chemistry	715:741	different surface chemistry	715:741	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	2	42	theme	physico-chemical	400:415	arg1	properties					417:426	physico-chemical properties	400:426	physico-chemical properties	400:426	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	12	43	theme	chromosome	1769:1778	arg1	damage					1780:1785	chromosome damage	1769:1785	chromosome damage (measured by the micronucleus assay)	1769:1822	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	7	44	theme	group	1251:1255	arg1	density					1257:1263	its high surface group density	1234:1263	its high surface group density	1234:1263	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	11	45	theme	dose-dependent	1609:1622	arg1	formation					1638:1646	a dose-dependent intracellular formation	1607:1646	a dose-dependent intracellular formation of reactive oxygen species (ROS)	1607:1679	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	8	46	theme	culture	1353:1359	arg1	medium					1361:1366	cell culture medium	1348:1366	cell culture medium	1348:1366	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	2	47	theme	thorough	336:343	arg1	assessment					354:363	a thorough toxicity assessment	334:363	a thorough toxicity assessment	334:363	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	13	48	theme	genotoxic	2087:2095	arg1	effects					2097:2103	genotoxic effects	2087:2103	genotoxic effects	2087:2103	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	7	49	theme	high	1238:1241	arg1	density					1257:1263	its high surface group density	1234:1263	its high surface group density	1234:1263	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	11	50	theme	species	1667:1673	arg1	formation					1638:1646	a dose-dependent intracellular formation	1607:1646	a dose-dependent intracellular formation of reactive oxygen species (ROS)	1607:1679	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	13	51	theme	ROS	2052:2054	arg1	formation					2056:2064	the in vitro intracellular ROS formation	2025:2064	the in vitro intracellular ROS formation	2025:2064	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	12	52	theme	comet	1752:1756	arg1	assay					1758:1762	the comet assay	1748:1762	the comet assay	1748:1762	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	4	53	dep	fractions	661:669	arg1	medium					678:683	medium	678:683	medium	678:683	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	53	dep	fractions	661:669	arg1	fine					672:675	fine	672:675	fine	672:675	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	53	dep	fractions	661:669	arg1	coarse					689:694	coarse	689:694	coarse	689:694	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	6	54	theme	CNF	1074:1076	arg1	samples					1078:1084	the functionalized CNF samples	1055:1084	the functionalized CNF samples	1055:1084	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	11	55	theme	reactive	1651:1658	arg1	ROS					1676:1678	ROS	1676:1678	ROS	1676:1678	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	11	55	theme	reactive	1651:1658	arg1	species					1667:1673	reactive oxygen species	1651:1673	reactive oxygen species (ROS)	1651:1679	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	4	56	theme	functionalized	767:780	arg1	fractions					661:669	three size fractions	650:669	three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	650:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	10	57	theme	cytotoxic	1469:1477	arg1	effects					1479:1485	No remarkable cytotoxic effects	1455:1485	No remarkable cytotoxic effects	1455:1485	No remarkable cytotoxic effects were induced by any of the cellulosic materials.					
35296350	6	58	attach	presence	1013:1020	arg2	groups					1045:1050	the surface charged groups	1025:1050	the surface charged groups	1025:1050	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	6	58	attach	presence	1013:1020	arg1	samples					1078:1084	the functionalized CNF samples	1055:1084	the functionalized CNF samples	1055:1084	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	11	59	theme	cellulosic	1540:1549	arg1	materials					1551:1559	All cellulosic materials	1536:1559	All cellulosic materials	1536:1559	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	15	60	theme	physico-chemical	2417:2432	arg1	properties					2434:2443	their physico-chemical properties	2411:2443	their physico-chemical properties	2411:2443	However, the conclusions cannot be generalized to all types of CNFs, as the synthesis process and the dispersion method used for testing affect their physico-chemical properties and, hence, their toxic effects.					
35296350	12	61	theme	fine	1686:1689	arg1	fraction					1691:1698	The fine fraction	1682:1698	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay),	1682:1823	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	6	62	theme	groups	1045:1050	arg1	presence					1013:1020	The presence	1009:1020	The presence of the surface charged groups in the functionalized CNF samples	1009:1084	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	12	63	dep	damage	1780:1785	arg1	measured					1788:1795	measured	1788:1795	measured by the micronucleus assay	1788:1821	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	14	64	theme	ROS	2251:2253	arg1	generation					2255:2264	ROS generation	2251:2264	ROS generation	2251:2264	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	1	65	theme	applications	260:271	arg1	range					251:255	a broad range	243:255	a broad range of applications	243:271	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	12	66	theme	ROS	1937:1939	arg1	induction					1924:1932	the most effective induction	1905:1932	the most effective induction of ROS in their respective size fractions	1905:1974	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	14	67	dep	cationic	2136:2143	arg1	CNF					2189:2191	CNF	2189:2191	CNF	2189:2191	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	7	68	with	agreement	1219:1227	arg1	density					1257:1263	its high surface group density	1234:1263	its high surface group density	1234:1263	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	2	69	theme	fibrous	278:284	arg1	nature					286:291	fibrous nature	278:291	fibrous nature	278:291	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	7	70	from	agreement	1219:1227	arg1	T-CNF					1185:1189	T-CNF	1185:1189	T-CNF	1185:1189	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	7	70	from	agreement	1219:1227	arg1	homogenous					1204:1213	homogenous	1204:1213	homogenous	1204:1213	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	6	71	theme	nanofibrils	1127:1137	arg1	amounts					1105:1111	higher amounts	1098:1111	higher amounts of individual nanofibrils	1098:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	6	71	theme	nanofibrils	1127:1137	arg1	nanofibrils					1127:1137	individual nanofibrils	1116:1137	individual nanofibrils	1116:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	11	72	theme	U-CNF	1592:1596	arg1	fraction					1580:1587	the medium fraction	1569:1587	the medium fraction of U-CNF	1569:1596	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	2	73	theme	CNFs	320:323	arg1	nature					286:291	fibrous nature	278:291	fibrous nature	278:291	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	2	73	theme	CNFs	320:323	arg1	biopersistence					302:315	high biopersistence	297:315	high biopersistence	297:315	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	10	74	theme	cellulosic	1514:1523	arg1	materials					1525:1533	the cellulosic materials	1510:1533	the cellulosic materials	1510:1533	No remarkable cytotoxic effects were induced by any of the cellulosic materials.					
35296350	14	75	theme	genotoxic	2208:2216	arg1	effects					2218:2224	primary genotoxic effects	2200:2224	primary genotoxic effects	2200:2224	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	1	76	theme	sustainable	191:201	arg1	option					232:237	a sustainable and environmentally friendly option	189:237	a sustainable and environmentally friendly option for a broad range of applications	189:271	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	6	77	theme	higher	1098:1103	arg1	amounts					1105:1111	higher amounts	1098:1111	higher amounts of individual nanofibrils	1098:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	6	77	theme	higher	1098:1103	arg1	nanofibrils					1127:1137	individual nanofibrils	1116:1137	individual nanofibrils	1116:1137	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	3	78	theme	CNFs	588:591	arg1	genotoxicity					572:583	the genotoxicity	568:583	the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells	568:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	1	79	theme	environmentally	207:221	arg1	option					232:237	a sustainable and environmentally friendly option	189:237	a sustainable and environmentally friendly option for a broad range of applications	189:271	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	8	80	theme	T-CNF	1395:1399	arg1	case					1387:1390	the case	1383:1390	the case of T-CNF	1383:1399	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	12	81	theme	coarse	1833:1838	arg1	fraction					1840:1847	the coarse fraction	1829:1847	the coarse fraction of C-CNF, which produced chromosome damage,	1829:1891	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	14	82	theme	primary	2200:2206	arg1	effects					2218:2224	primary genotoxic effects	2200:2224	primary genotoxic effects	2200:2224	One cationic (fine E-CNF) and one anionic (coarse C-CNF) CNF showed primary genotoxic effects, possibly partly through ROS generation.					
35296350	3	83	theme	epithelial	612:621	arg1	cells					631:635	human bronchial epithelial BEAS-2B cells	596:635	human bronchial epithelial BEAS-2B cells	596:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	1	84	theme	BACKGROUND	133:142	arg1	CNFs					167:170	CNFs	167:170	CNFs	167:170	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	1	84	theme	BACKGROUND	133:142	arg1	nanofibrils					154:164	BACKGROUND Cellulose nanofibrils	133:164	BACKGROUND Cellulose nanofibrils (CNFs)	133:171	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
35296350	4	85	theme	epoxypropyltrimethylammonium	867:894	arg1	EPTMAC					906:911	EPTMAC	906:911	EPTMAC	906:911	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	85	theme	epoxypropyltrimethylammonium	867:894	arg1	E-CNF					915:919	E-CNF	915:919	E-CNF	915:919	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	85	theme	epoxypropyltrimethylammonium	867:894	arg1	chloride					896:903	epoxypropyltrimethylammonium chloride	867:903	epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	867:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	12	86	theme	respective	1950:1959	arg1	fractions					1966:1974	their respective size fractions	1944:1974	their respective size fractions	1944:1974	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	0	87	theme	oxygen	70:75	arg1	species					77:83	reactive oxygen species	61:83	reactive oxygen species	61:83	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	13	88	theme	Surface	1989:1995	arg1	CONCLUSIONS					1977:1987	CONCLUSIONS Surface chemistry and size	1977:2014	CONCLUSIONS Surface chemistry and size	1977:2014	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	13	88	theme	Surface	1989:1995	arg1	chemistry					1997:2005	Surface chemistry	1989:2005	Surface chemistry	1989:2005	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	3	89	theme	human	596:600	arg1	cells					631:635	human bronchial epithelial BEAS-2B cells	596:635	human bronchial epithelial BEAS-2B cells	596:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	9	90	theme	BEAS-2B	1440:1446	arg1	cells					1448:1452	BEAS-2B cells	1440:1452	BEAS-2B cells	1440:1452	CNF was internalized by a minority of BEAS-2B cells.					
35296350	12	91	theme	effective	1914:1922	arg1	induction					1924:1932	the most effective induction	1905:1932	the most effective induction of ROS in their respective size fractions	1905:1974	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	2	92	dep	nature	286:291	arg1	The					274:276	The	274:276	The	274:276	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	0	93	theme	cellulose	110:118	arg1	nanofibrils					120:130	cellulose nanofibrils	110:130	cellulose nanofibrils	110:130	Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils.					
35296350	6	94	theme	charged	1037:1043	arg1	groups					1045:1050	the surface charged groups	1025:1050	the surface charged groups	1025:1050	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	4	95	theme	unmodified	744:753	arg1	fractions					661:669	three size fractions	650:669	three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	650:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	96	dep	unmodified	744:753	arg1	U-CNF					756:760	U-CNF	756:760	U-CNF	756:760	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	4	97	theme	CNFs	705:708	arg1	fractions					661:669	three size fractions	650:669	three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF)	650:920	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	3	98	from	genotoxicity	572:583	arg1	cells					631:635	human bronchial epithelial BEAS-2B cells	596:635	human bronchial epithelial BEAS-2B cells	596:635	Here, we assessed whether surface composition and size could modulate the genotoxicity of CNFs in human bronchial epithelial BEAS-2B cells.					
35296350	13	99	theme	fibrillated	2108:2118	arg1	celluloses					2120:2129	fibrillated celluloses	2108:2129	fibrillated celluloses	2108:2129	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	11	100	theme	intracellular	1624:1636	arg1	formation					1638:1646	a dose-dependent intracellular formation	1607:1646	a dose-dependent intracellular formation of reactive oxygen species (ROS)	1607:1679	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	4	101	theme	different	715:723	arg1	chemistry					733:741	different surface chemistry	715:741	different surface chemistry	715:741	We examined three size fractions (fine, medium and coarse) of four CNFs with different surface chemistry: unmodified (U-CNF) and functionalized with 2,2,6,6-tetramethyl-piperidin-1-oxyl (TEMPO) (T-CNF), carboxymethyl (C-CNF) and epoxypropyltrimethylammonium chloride (EPTMAC) (E-CNF).					
35296350	12	102	dep	damage	1728:1733	arg1	measured					1736:1743	measured	1736:1743	measured by the comet assay	1736:1762	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	7	103	theme	surface	1243:1249	arg1	density					1257:1263	its high surface group density	1234:1263	its high surface group density	1234:1263	T-CNF was the most homogenous, in agreement with its high surface group density.					
35296350	2	104	theme	potential	465:473	arg1	response					481:488	the potential toxic response	461:488	the potential toxic response to CNF	461:495	The fibrous nature and high biopersistence of CNFs call for a thorough toxicity assessment, but it is presently unclear which physico-chemical properties could play a role in determining the potential toxic response to CNF.					
35296350	5	105	theme	non-nanosized	977:989	arg1	source					940:945	the source fibre	936:951	the source fibre	936:951	In addition, the source fibre was also evaluated as a non-nanosized material.					
35296350	5	105	theme	non-nanosized	977:989	arg1	material					991:998	a non-nanosized material	975:998	a non-nanosized material	975:998	In addition, the source fibre was also evaluated as a non-nanosized material.					
35296350	12	106	theme	DNA	1724:1726	arg1	damage					1728:1733	DNA damage	1724:1733	DNA damage (measured by the comet assay)	1724:1763	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	11	107	theme	oxygen	1660:1665	arg1	ROS					1676:1678	ROS	1676:1678	ROS	1676:1678	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	11	107	theme	oxygen	1660:1665	arg1	species					1667:1673	reactive oxygen species	1651:1673	reactive oxygen species (ROS)	1651:1679	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	8	108	theme	cell	1348:1351	arg1	medium					1361:1366	cell culture medium	1348:1366	cell culture medium	1348:1366	However, the colloidal stability of all the CNF samples dropped when dispersed in cell culture medium, especially in the case of T-CNF.					
35296350	13	109	theme	effects	2097:2103	arg1	formation					2056:2064	the in vitro intracellular ROS formation	2025:2064	the in vitro intracellular ROS formation	2025:2064	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	13	109	theme	effects	2097:2103	arg1	induction					2074:2082	the induction	2070:2082	the induction of genotoxic effects by fibrillated celluloses	2070:2129	CONCLUSIONS Surface chemistry and size modulate the in vitro intracellular ROS formation and the induction of genotoxic effects by fibrillated celluloses.					
35296350	5	110	theme	fibre	947:951	arg1	material					991:998	a non-nanosized material	975:998	a non-nanosized material	975:998	In addition, the source fibre was also evaluated as a non-nanosized material.					
35296350	5	110	theme	fibre	947:951	arg1	source					940:945	the source fibre	936:951	the source fibre	936:951	In addition, the source fibre was also evaluated as a non-nanosized material.					
35296350	12	111	theme	E-CNF	1703:1707	arg1	fraction					1840:1847	the coarse fraction	1829:1847	the coarse fraction of C-CNF, which produced chromosome damage,	1829:1891	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	12	111	theme	E-CNF	1703:1707	arg1	fraction					1691:1698	The fine fraction	1682:1698	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay),	1682:1823	The fine fraction of E-CNF, which induced DNA damage (measured by the comet assay) and chromosome damage (measured by the micronucleus assay), and the coarse fraction of C-CNF, which produced chromosome damage, also showed the most effective induction of ROS in their respective size fractions.					
35296350	6	112	theme	functionalized	1059:1072	arg1	samples					1078:1084	the functionalized CNF samples	1055:1084	the functionalized CNF samples	1055:1084	RESULTS The presence of the surface charged groups in the functionalized CNF samples resulted in higher amounts of individual nanofibrils and less aggregation compared with the U-CNF.					
35296350	11	113	theme	medium	1573:1578	arg1	fraction					1580:1587	the medium fraction	1569:1587	the medium fraction of U-CNF	1569:1596	All cellulosic materials, except the medium fraction of U-CNF, induced a dose-dependent intracellular formation of reactive oxygen species (ROS).					
35296350	1	114	theme	broad	245:249	arg1	range					251:255	a broad range	243:255	a broad range of applications	243:271	BACKGROUND Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications.					
36746593	0	0	theme	nanocellulose	85:97	arg1	vessel					116:121	bacterial nanocellulose artificial blood vessel	75:121	bacterial nanocellulose artificial blood vessel after mercerization	75:141	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	2	1	theme	shape	528:532	arg1	controllability					534:548	its shape controllability	524:548	its shape controllability	524:548	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	4	2	theme	NaOH	912:915	arg1	treatment					918:926	controlled alkali (NaOH) treatment	893:926	controlled alkali (NaOH) treatment	893:926	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	1	3	theme	caliber	174:180	arg1	vessels					199:205	small caliber artificial blood vessels	168:205	small caliber artificial blood vessels	168:205	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	7	4	theme	cells	1515:1519	arg1	behaviors					1493:1501	behaviors	1493:1501	behaviors	1493:1501	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	7	4	theme	cells	1515:1519	arg1	functions					1479:1487	functions	1479:1487	functions	1479:1487	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	0	5	theme	bacterial	75:83	arg1	vessel					116:121	bacterial nanocellulose artificial blood vessel	75:121	bacterial nanocellulose artificial blood vessel after mercerization	75:141	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	3	6	theme	vascular	738:745	arg1	cells					747:751	vascular cells	738:751	vascular cells	738:751	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	1	7	theme	artificial	182:191	arg1	vessels					199:205	small caliber artificial blood vessels	168:205	small caliber artificial blood vessels	168:205	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	1	8	theme	low	279:281	arg1	patency					283:289	their low patency	273:289	their low patency	273:289	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	0	9	theme	blood	110:114	arg1	vessel					116:121	bacterial nanocellulose artificial blood vessel	75:121	bacterial nanocellulose artificial blood vessel after mercerization	75:141	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	3	10	theme	cells	747:751	arg1	behaviors					725:733	behaviors	725:733	behaviors of vascular cells	725:751	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	5	11	theme	cell	1069:1072	arg1	density					1082:1088	the cell seeding density	1065:1088	the cell seeding density	1065:1088	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	5	11	theme	cell	1069:1072	arg1	meanwhile					1054:1062	meanwhile	1054:1062	meanwhile	1054:1062	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	2	12	theme	Bacterial	325:333	arg1	BNC					350:352	BNC	350:352	BNC	350:352	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	2	12	theme	Bacterial	325:333	arg1	nanocellulose					335:347	Bacterial nanocellulose	325:347	Bacterial nanocellulose (BNC)	325:353	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	5	13	theme	expression	1042:1051	arg1	behaviors					1005:1013	the behaviors	1001:1013	the behaviors of vascular cells and gene expression	1001:1051	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	0	14	theme	artificial	99:108	arg1	vessel					116:121	bacterial nanocellulose artificial blood vessel	75:121	bacterial nanocellulose artificial blood vessel after mercerization	75:141	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	7	15	theme	conduits	1619:1626	arg1	patency					1598:1604	the long-term patency	1584:1604	the long-term patency of BNC-based conduits	1584:1626	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	5	16	theme	vascular	1018:1025	arg1	cells					1027:1031	vascular cells	1018:1031	vascular cells	1018:1031	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	6	17	theme	gene	1258:1261	arg1	expressions					1263:1273	several functional gene expressions	1239:1273	several functional gene expressions of human vascular endothelial cells	1239:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	4	18	theme	BNC	806:808	arg1	conduits					810:817	mercerized BNC conduits	795:817	mercerized BNC conduits (MBNC) with different surface roughness and stiffness	795:871	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	4	18	theme	BNC	806:808	arg1	MBNC					820:823	MBNC	820:823	MBNC	820:823	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	6	19	theme	%	1173:1173	arg1	NaOH					1149:1152	NaOH	1149:1152	NaOH concentration > 10 %	1149:1173	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	7	20	theme	important	1542:1550	arg1	parameters					1562:1571	important designing parameters	1542:1571	important designing parameters	1542:1571	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	5	21	theme	surface	944:950	arg1	structures					952:961	surface structures	944:961	surface structures	944:961	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	5	22	theme	cells	1027:1031	arg1	behaviors					1005:1013	the behaviors	1001:1013	the behaviors of vascular cells and gene expression	1001:1051	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	7	23	theme	physical	1410:1417	arg1	structure					1427:1435	physical surface structure	1410:1435	physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits	1410:1626	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	1	24	theme	blood	193:197	arg1	vessels					199:205	small caliber artificial blood vessels	168:205	small caliber artificial blood vessels	168:205	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	0	25	theme	vessel	116:121	arg1	properties					61:70	properties	61:70	properties	61:70	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	0	25	theme	vessel	116:121	arg1	structure					47:55	surface structure	39:55	surface structure	39:55	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	2	26	theme	small-caliber	475:487	arg1	applications					504:515	small-caliber vascular graft applications	475:515	small-caliber vascular graft applications	475:515	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	2	27	theme	Komagataeibatacter	418:435	arg1	xylinus					437:443	a bacterium Komagataeibatacter xylinus	406:443	a bacterium Komagataeibatacter xylinus	406:443	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	0	28	theme	cells	9:13	arg1	responses					15:23	Vascular cells responses	0:23	Vascular cells responses to	0:26	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	6	29	theme	increased	1201:1209	arg1	stiffness					1211:1219	the increased stiffness	1197:1219	the increased stiffness of MBNC	1197:1227	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	4	30	theme	alkali	904:909	arg1	treatment					918:926	controlled alkali (NaOH) treatment	893:926	controlled alkali (NaOH) treatment	893:926	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	6	31	theme	cells	1305:1309	arg1	expressions					1263:1273	several functional gene expressions	1239:1273	several functional gene expressions of human vascular endothelial cells	1239:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	6	32	with	mercerization	1130:1142	arg1	NaOH					1149:1152	NaOH	1149:1152	NaOH concentration > 10 %	1149:1173	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	2	33	theme	bacterium	408:416	arg1	xylinus					437:443	a bacterium Komagataeibatacter xylinus	406:443	a bacterium Komagataeibatacter xylinus	406:443	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	0	34	theme	Vascular	0:7	arg1	responses					15:23	Vascular cells responses	0:23	Vascular cells responses to	0:26	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	1	35	theme	long-term	298:306	arg1	transplantation					308:322	long-term transplantation	298:322	long-term transplantation	298:322	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	4	36	theme	controlled	893:902	arg1	treatment					918:926	controlled alkali (NaOH) treatment	893:926	controlled alkali (NaOH) treatment	893:926	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	1	37	theme	cure	210:213	arg1	cardio					215:220	cure cardio	210:220	cure cardio	210:220	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	7	38	theme	MBNC	1440:1443	arg1	conduits					1445:1452	MBNC conduits	1440:1452	MBNC conduits	1440:1452	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	6	39	theme	functional	1247:1256	arg1	expressions					1263:1273	several functional gene expressions	1239:1273	several functional gene expressions of human vascular endothelial cells	1239:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	7	40	theme	surface	1419:1425	arg1	structure					1427:1435	physical surface structure	1410:1435	physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits	1410:1626	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	4	41	theme	mercerized	795:804	arg1	conduits					810:817	mercerized BNC conduits	795:817	mercerized BNC conduits (MBNC) with different surface roughness and stiffness	795:871	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	4	41	theme	mercerized	795:804	arg1	MBNC					820:823	MBNC	820:823	MBNC	820:823	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	6	42	theme	endothelial	1293:1303	arg1	cells					1305:1309	human vascular endothelial cells	1278:1309	human vascular endothelial cells	1278:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	2	43	theme	great	456:460	arg1	potential					462:470	great potential	456:470	great potential in small-caliber vascular graft applications due to its shape controllability	456:548	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	4	44	with	conduits	810:817	arg1	stiffness					863:871	stiffness	863:871	stiffness	863:871	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	4	44	with	conduits	810:817	arg1	roughness					849:857	different surface roughness	831:857	different surface roughness	831:857	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	5	45	theme	cell	1108:1111	arg1	responses					1113:1121	the cell responses	1104:1121	the cell responses	1104:1121	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	0	46	theme	surface	39:45	arg1	structure					47:55	surface structure	39:55	surface structure	39:55	Vascular cells responses to controlled surface structure and properties of bacterial nanocellulose artificial blood vessel after mercerization.					
36746593	6	47	theme	human	1278:1282	arg1	cells					1305:1309	human vascular endothelial cells	1278:1309	human vascular endothelial cells	1278:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	3	48	theme	BNC	709:711	arg1	conduits					713:720	BNC conduits	709:720	BNC conduits	709:720	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	6	49	theme	smooth	1351:1356	arg1	cells					1365:1369	smooth muscle cells	1351:1369	smooth muscle cells	1351:1369	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	3	50	from	influences	650:659	arg1	behaviors					725:733	behaviors	725:733	behaviors of vascular cells	725:751	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	1	51	theme	cerebrovascular	226:240	arg1	diseases					242:249	cerebrovascular diseases	226:249	cerebrovascular diseases	226:249	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	7	52	theme	designing	1552:1560	arg1	parameters					1562:1571	important designing parameters	1542:1571	important designing parameters	1542:1571	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	2	53	theme	surface	580:586	arg1	structure					588:596	its physical surface structure	567:596	its physical surface structure	567:596	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	7	54	theme	BNC-based	1609:1617	arg1	conduits					1619:1626	BNC-based conduits	1609:1626	BNC-based conduits	1609:1626	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	6	55	theme	vascular	1284:1291	arg1	cells					1305:1309	human vascular endothelial cells	1278:1309	human vascular endothelial cells	1278:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	6	56	theme	pathological	1320:1331	arg1	transformation					1333:1346	the pathological transformation	1316:1346	the pathological transformation of smooth muscle cells	1316:1369	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	2	57	theme	physical	571:578	arg1	structure					588:596	its physical surface structure	567:596	its physical surface structure	567:596	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	3	58	theme	properties	695:704	arg1	influences					650:659	influences	650:659	influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells	650:751	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	2	59	from	potential	462:470	arg1	applications					504:515	small-caliber vascular graft applications	475:515	small-caliber vascular graft applications	475:515	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	2	60	theme	natural	361:367	arg1	polysaccharide					369:382	a natural polysaccharide	359:382	a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus	359:443	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	2	61	theme	graft	498:502	arg1	applications					504:515	small-caliber vascular graft applications	475:515	small-caliber vascular graft applications	475:515	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	6	62	theme	MBNC	1224:1227	arg1	stiffness					1211:1219	the increased stiffness	1197:1219	the increased stiffness of MBNC	1197:1227	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	2	63	theme	different	619:627	arg1	treatments					629:638	different treatments	619:638	different treatments	619:638	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	5	64	theme	seeding	1074:1080	arg1	density					1082:1088	the cell seeding density	1065:1088	the cell seeding density	1065:1088	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	5	64	theme	seeding	1074:1080	arg1	meanwhile					1054:1062	meanwhile	1054:1062	meanwhile	1054:1062	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	7	65	theme	vascular	1506:1513	arg1	cells					1515:1519	vascular cells	1506:1519	vascular cells	1506:1519	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	5	66	theme	structures	952:961	arg1	changes					933:939	The changes	929:939	The changes of surface structures and properties	929:976	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	4	67	theme	different	831:839	arg1	roughness					849:857	different surface roughness	831:857	different surface roughness	831:857	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	6	68	theme	cells	1365:1369	arg1	transformation					1333:1346	the pathological transformation	1316:1346	the pathological transformation of smooth muscle cells	1316:1369	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	5	69	theme	gene	1037:1040	arg1	expression					1042:1051	gene expression	1037:1051	gene expression	1037:1051	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	3	70	theme	surface	673:679	arg1	structure					681:689	physical surface structure	664:689	physical surface structure	664:689	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	1	71	theme	Therapeutic	144:154	arg1	benefits					156:163	Therapeutic benefits	144:163	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases	144:249	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	6	72	theme	muscle	1358:1363	arg1	cells					1365:1369	smooth muscle cells	1351:1369	smooth muscle cells	1351:1369	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	3	73	theme	conduits	713:720	arg1	properties					695:704	properties	695:704	properties of BNC conduits	695:720	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	3	73	theme	conduits	713:720	arg1	structure					681:689	physical surface structure	664:689	physical surface structure	664:689	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	3	74	theme	structure	681:689	arg1	influences					650:659	influences	650:659	influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells	650:751	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	5	75	theme	properties	967:976	arg1	changes					933:939	The changes	929:939	The changes of surface structures and properties	929:976	The changes of surface structures and properties significantly affected the behaviors of vascular cells and gene expression; meanwhile, the cell seeding density also affected the cell responses.					
36746593	6	76	theme	several	1239:1245	arg1	expressions					1263:1273	several functional gene expressions	1239:1273	several functional gene expressions of human vascular endothelial cells	1239:1309	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	7	77	theme	long-term	1588:1596	arg1	patency					1598:1604	the long-term patency	1584:1604	the long-term patency of BNC-based conduits	1584:1626	This study demonstrates physical surface structure of MBNC conduits will critically regulate functions and behaviors of vascular cells and it also provides important designing parameters to improve the long-term patency of BNC-based conduits.					
36746593	4	78	theme	surface	841:847	arg1	roughness					849:857	different surface roughness	831:857	different surface roughness	831:857	In this work, mercerized BNC conduits (MBNC) with different surface roughness and stiffness were constructed by controlled alkali (NaOH) treatment.					
36746593	6	79	theme	concentration > 10 	1154:1172	arg1	%					1173:1173	%	1173:1173	%	1173:1173	After mercerization with NaOH concentration > 10 %, it was observed that the increased stiffness of MBNC decreased several functional gene expressions of human vascular endothelial cells, and the pathological transformation of smooth muscle cells was inhibited.					
36746593	1	80	theme	vessels	199:205	arg1	benefits					156:163	Therapeutic benefits	144:163	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases	144:249	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
36746593	2	81	theme	vascular	489:496	arg1	applications					504:515	small-caliber vascular graft applications	475:515	small-caliber vascular graft applications	475:515	Bacterial nanocellulose (BNC), as a natural polysaccharide mainly synthesized by a bacterium Komagataeibatacter xylinus, has shown great potential in small-caliber vascular graft applications due to its shape controllability, and furthermore its physical surface structure can be adjusted with different treatments.					
36746593	3	82	theme	physical	664:671	arg1	structure					681:689	physical surface structure	664:689	physical surface structure	664:689	However, influences of physical surface structure and properties of BNC conduits on behaviors of vascular cells have not been investigated.					
36746593	1	83	theme	small	168:172	arg1	vessels					199:205	small caliber artificial blood vessels	168:205	small caliber artificial blood vessels	168:205	Therapeutic benefits of small caliber artificial blood vessels to cure cardio and cerebrovascular diseases are mainly limited by their low patency during long-term transplantation.					
35989034	4	0	theme	carbohydrate	989:1000	arg1	assays					1002:1007	bicinchoninic acid protein and glycoprotein carbohydrate assays	945:1007	assays	1002:1007	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	1	1	from	°C	325:326	arg1	mechanism					309:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism	235:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C	235:326	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	4	2	theme	glycoprotein	976:987	arg1	assays					1002:1007	bicinchoninic acid protein and glycoprotein carbohydrate assays	945:1007	assays	1002:1007	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	2	3	from	influences	333:342	arg1	reaction					400:407	the reaction	396:407	the reaction	396:407	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	2	4	theme	pH	362:363	arg1	influences					333:342	The influences	329:342	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction	329:407	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	4	5	theme	BSA	771:773	arg1	°C					804:805	80 °C	801:805	80 °C	801:805	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	5	theme	BSA	771:773	arg1	temperature					788:798	the BSA denaturation temperature	767:798	the BSA denaturation temperature (80 °C)	767:806	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	1	6	theme	Schiff	263:268	arg1	rearrangement					295:307	a Schiff base-Amadori solid phase rearrangement	261:307	a Schiff base-Amadori solid phase rearrangement	261:307	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	2	7	theme	water	515:519	arg1	by-product					521:530	the water by-product	511:530	the water by-product	511:530	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	4	8	theme	195-400 nm	867:876	arg1	diameter					855:862	a hydrodynamic diameter	840:862	a hydrodynamic diameter of 195-400 nm	840:876	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	1	9	theme	base-Amadori	270:281	arg1	rearrangement					295:307	a Schiff base-Amadori solid phase rearrangement	261:307	a Schiff base-Amadori solid phase rearrangement	261:307	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	4	10	theme	acid	959:962	arg1	protein					964:970	bicinchoninic acid protein and glycoprotein carbohydrate assays	945:1007	protein	964:970	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	11	theme	dextran-BSA	717:727	arg1	solution					739:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	12	gly	glycoprotein	976:987	arg1	glycoprotein					976:987	bicinchoninic acid protein and glycoprotein carbohydrate assays	945:1007	glycoprotein	976:987	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	2	13	theme	molar	381:385	arg1	ratio					387:391	dextran:BSA molar ratio	369:391	dextran:BSA molar ratio	369:391	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	1	14	theme	dextran-bovine	176:189	arg1	albumin					197:203	dextran-bovine serum albumin	176:203	dextran-bovine serum albumin (BSA) model conjugate	176:225	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	1	14	theme	dextran-bovine	176:189	arg1	BSA					206:208	BSA	206:208	BSA	206:208	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	4	15	theme	bicinchoninic	945:957	arg1	protein					964:970	bicinchoninic acid protein and glycoprotein carbohydrate assays	945:1007	protein	964:970	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	16	theme	denaturation	775:786	arg1	°C					804:805	80 °C	801:805	80 °C	801:805	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	16	theme	denaturation	775:786	arg1	temperature					788:798	the BSA denaturation temperature	767:798	the BSA denaturation temperature (80 °C)	767:806	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	1	17	theme	serum	191:195	arg1	albumin					197:203	dextran-bovine serum albumin	176:203	dextran-bovine serum albumin (BSA) model conjugate	176:225	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	1	17	theme	serum	191:195	arg1	BSA					206:208	BSA	206:208	BSA	206:208	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	2	18	theme	highest	436:442	arg1	yields					444:449	the highest yields	432:449	the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum	432:543	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	4	19	theme	hydrodynamic	842:853	arg1	diameter					855:862	a hydrodynamic diameter	840:862	a hydrodynamic diameter of 195-400 nm	840:876	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	1	20	theme	albumin	197:203	arg1	conjugate					217:225	dextran-bovine serum albumin (BSA) model conjugate	176:225	dextran-bovine serum albumin (BSA) model conjugate	176:225	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	0	21	theme	Innovative	0:9	arg1	process					11:17	Innovative process	0:17	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.	0:121	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	1	22	theme	solid	283:287	arg1	rearrangement					295:307	a Schiff base-Amadori solid phase rearrangement	261:307	a Schiff base-Amadori solid phase rearrangement	261:307	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	3	23	theme	higher	578:583	arg1	yields					585:590	higher yields	578:590	higher yields	578:590	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	2	24	theme	BSA	377:379	arg1	ratio					387:391	dextran:BSA molar ratio	369:391	dextran:BSA molar ratio	369:391	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	0	25	theme	facile	23:28	arg1	synthesis					69:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	1	26	theme	phase	289:293	arg1	rearrangement					295:307	a Schiff base-Amadori solid phase rearrangement	261:307	a Schiff base-Amadori solid phase rearrangement	261:307	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	1	27	theme	rearrangement	295:307	arg1	mechanism					309:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism	235:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C	235:326	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	4	28	theme	conjugate	910:918	arg1	composition					920:930	the conjugate composition	906:930	the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays	906:1007	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	0	29	theme	serum	45:49	arg1	synthesis					69:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	3	30	theme	higher	653:658	arg1	reactivity					660:669	higher reactivity	653:669	higher reactivity of deprotonated amine at pH 7.8	653:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	1	31	theme	model	211:215	arg1	conjugate					217:225	dextran-bovine serum albumin (BSA) model conjugate	176:225	dextran-bovine serum albumin (BSA) model conjugate	176:225	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	0	32	theme	dextran-bovine	30:43	arg1	synthesis					69:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	3	33	from	pH 7.8	696:701	arg1	reactivity					660:669	higher reactivity	653:669	higher reactivity of deprotonated amine at pH 7.8	653:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	3	33	from	pH 7.8	696:701	arg1	amine					687:691	deprotonated amine	674:691	deprotonated amine at pH 7.8	674:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	0	34	theme	conjugate	59:67	arg1	synthesis					69:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	2	35	theme	lyophilization	347:360	arg1	pH					362:363	lyophilization pH	347:363	lyophilization pH	347:363	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	0	36	theme	albumin	51:57	arg1	synthesis					69:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	facile dextran-bovine serum albumin conjugate synthesis	23:77	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	3	37	theme	deprotonated	674:685	arg1	amine					687:691	deprotonated amine	674:691	deprotonated amine at pH 7.8	674:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	4	38	theme	purified	708:715	arg1	solution					739:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	4	39	theme	dependent	893:901	arg1	size					888:891	the size	884:891	the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays	884:1007	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	3	40	theme	amine	687:691	arg1	reactivity					660:669	higher reactivity	653:669	higher reactivity of deprotonated amine at pH 7.8	653:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	1	41	theme	process	129:135	arg1	variations					137:146	Three process variations	123:146	Three process variations	123:146	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	4	42	theme	conjugate	729:737	arg1	solution					739:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution	704:746	The purified dextran-BSA conjugate solution is heated to above the BSA denaturation temperature (80 °C) at pH 5.2 to form nanogels with a hydrodynamic diameter of 195-400 nm, with the size dependent on the conjugate composition estimated by bicinchoninic acid protein and glycoprotein carbohydrate assays.					
35989034	3	43	from	reactivity	660:669	arg1	pH 7.8					696:701	pH 7.8	696:701	pH 7.8	696:701	Lyophilizing at pH 7.8 provides higher yields than materials lyophilized at pH 5.9, a result attributed to higher reactivity of deprotonated amine at pH 7.8.					
35989034	0	44	dep	process	11:17	arg1	Mechanism					80:88	Mechanism	80:88	Mechanism	80:88	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	0	44	dep	process	11:17	arg1	kinetics					91:98	kinetics	91:98	kinetics	91:98	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	0	44	dep	process	11:17	arg1	characterization					105:120	characterization	105:120	characterization	105:120	Innovative process for facile dextran-bovine serum albumin conjugate synthesis: Mechanism, kinetics, and characterization.					
35989034	2	45	theme	ratio	387:391	arg1	influences					333:342	The influences	329:342	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction	329:407	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	1	46	theme	Maillard	239:246	arg1	reaction					248:255	the Maillard reaction	235:255	the Maillard reaction	235:255	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
35989034	2	47	theme	dextran	369:375	arg1	ratio					387:391	dextran:BSA molar ratio	369:391	dextran:BSA molar ratio	369:391	The influences of lyophilization pH and dextran:BSA molar ratio on the reaction are investigated, with the highest yields achieved by absorbing heat evenly and continuously removing the water by-product under vacuum.					
35989034	1	48	theme	reaction	248:255	arg1	mechanism					309:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism	235:317	the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C	235:326	Three process variations are developed to synthesize dextran-bovine serum albumin (BSA) model conjugate through the Maillard reaction and a Schiff base-Amadori solid phase rearrangement mechanism at 90 °C.					
36744829	14	0	with	treatment	1968:1976	arg1	chitosan					1983:1990	chitosan	1983:1990	chitosan	1983:1990	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	14	1	theme	lower	2029:2033	arg1	activity					2045:2052	lower enzymatic activity	2029:2052	lower enzymatic activity for RelyX ARC	2029:2066	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	1	2	theme	root	322:325	arg1	dentin					327:332	root dentin	322:332	root dentin	322:332	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	3	theme	chitosan	219:226	arg1	effect					186:191	the effect	182:191	the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite	182:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	13	4	dep	CONCLUSION	1716:1725	arg1	yielded					1818:1824	yielded	1818:1824	yielded different results depending on the adhesive used	1818:1873	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	13	5	theme	intraradicular	1796:1809	arg1	dentin					1811:1816	intraradicular dentin	1796:1816	intraradicular dentin	1796:1816	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	14	6	theme	higher	2004:2009	arg1	strength					2016:2023	higher bond strength	2004:2023	higher bond strength	2004:2023	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	1	7	theme	composite	301:309	arg1	strength					274:281	bond strength	269:281	bond strength (BS) of different composite	269:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	7	theme	composite	301:309	arg1	EA					261:262	EA	261:262	EA	261:262	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	7	theme	composite	301:309	arg1	BS					284:285	BS	284:285	BS	284:285	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	7	theme	composite	301:309	arg1	activity					251:258	the enzymatic activity	237:258	the enzymatic activity (EA)	237:263	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	7	8	theme	RelyX	1122:1126	arg1	U200					1128:1131	RelyX U200	1122:1131	RelyX U200	1122:1131	RESULTS RelyX ARC showed higher BS associated with CHI, while RelyX U200 showed higher BS associated with EDC (p = 0.044).					
36744829	4	9	theme	third	819:823	arg1	cervical					802:809	cervical	802:809	cervical	802:809	Of the slices obtained by sectioning, the most cervical of each third were subjected to a push-out test and the most apical were subjected to in-situ zymography.					
36744829	1	10	from	effect	186:191	arg1	strength					274:281	bond strength	269:281	bond strength (BS) of different composite	269:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	10	from	effect	186:191	arg1	EA					261:262	EA	261:262	EA	261:262	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	10	from	effect	186:191	arg1	BS					284:285	BS	284:285	BS	284:285	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	10	from	effect	186:191	arg1	activity					251:258	the enzymatic activity	237:258	the enzymatic activity (EA)	237:263	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	12	11	theme	greater	1609:1615	arg1	fluorescence					1617:1628	greater fluorescence	1609:1628	greater fluorescence	1609:1628	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	9	12	theme	RelyX	1381:1385	arg1	U200					1387:1390	RelyX U200	1381:1390	RelyX U200 (p < 0.001)	1381:1402	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	9	12	theme	RelyX	1381:1385	arg1	<					1395:1395	p < 0.001	1393:1401	p < 0.001	1393:1401	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	0	13	theme	Composite	128:136	arg1	Types					119:123	Different Types	109:123	Different Types of Composite	109:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	10	14	theme	adhesive-to-dentin	1431:1448	arg1	failures					1450:1457	adhesive-to-dentin failures	1431:1457	adhesive-to-dentin failures	1431:1457	The highest percentage of adhesive-to-dentin failures was observed for Panavia F 2.0.					
36744829	6	15	theme	chi-squared	1042:1052	arg1	test					1054:1057	the chi-squared test	1038:1057	the chi-squared test	1038:1057	The results were analyzed with ANOVA or the chi-squared test.					
36744829	13	16	theme	different	1731:1739	arg1	mechanisms					1741:1750	The different mechanisms	1727:1750	The different mechanisms of action of solutions for pre-treatment of intraradicular dentin	1727:1816	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	3	17	theme	dentin	526:531	arg1	treatment					533:541	dentin treatment	526:541	dentin treatment (distilled water [DW]	526:563	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	17	theme	dentin	526:531	arg1	water					554:558	distilled water [DW	544:562	distilled water [DW	544:562	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	18	dep	treated	472:478	arg1	RelyX					727:731	RelyX	727:731	RelyX	727:731	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	12	19	theme	p	1705:1705	arg1	>					1707:1707	p > 0.05	1705:1712	p > 0.05	1705:1712	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	3	20	theme	[3M	674:676	arg1	cement					656:661	composite cement	646:661	composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki]	646:721	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	20	theme	[3M	674:676	arg1	Care					683:686	RelyX ARC [3M Oral Care	664:686	RelyX ARC [3M Oral Care	664:686	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	12	21	theme	zymographic	1569:1579	arg1	analysis					1581:1588	zymographic analysis	1569:1588	zymographic analysis	1569:1588	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	3	22	dep	Care	683:686	arg1	Panavia					690:696	Panavia	690:696	Panavia	690:696	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	22	dep	Care	683:686	arg1	Noritaki					713:720	Noritaki	713:720	Noritaki	713:720	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	2	23	theme	roots	435:439	arg1	length					421:426	the length	417:426	the length of the roots	417:439	MATERIALS AND METHODS Ninety (90) maxillary canines were sectioned, standardizing the length of the roots.					
36744829	0	24	dep	Agents	50:55	arg1	Effect					57:62	Effect	57:62	Effect	57:62	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	3	25	theme	RelyX	664:668	arg1	cement					656:661	composite cement	646:661	composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki]	646:721	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	25	theme	RelyX	664:668	arg1	Care					683:686	RelyX ARC [3M Oral Care	664:686	RelyX ARC [3M Oral Care	664:686	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	14	26	theme	enzyme	1924:1929	arg1	inhibition					1931:1940	higher enzyme inhibition	1917:1940	higher enzyme inhibition	1917:1940	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	0	27	theme	Posts	92:96	arg1	Longevity					68:76	the Longevity	64:76	the Longevity of Fiberglass Posts Luted with Different Types of Composite	64:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	15	28	theme	Panavia	2146:2152	arg1	F					2154:2154	Panavia F 2.0	2146:2158	Panavia F 2.0	2146:2158	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	12	29	dep	all	1692:1694	arg1	cements					1696:1702	cements	1696:1702	cements	1696:1702	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	7	30	theme	higher	1085:1090	arg1	BS					1092:1093	higher BS	1085:1093	higher BS associated with CHI	1085:1113	RESULTS RelyX ARC showed higher BS associated with CHI, while RelyX U200 showed higher BS associated with EDC (p = 0.044).					
36744829	11	31	theme	failures	1546:1553	arg1	percentage					1513:1522	the lowest percentage	1502:1522	the lowest percentage of adhesive-to-dentin failures	1502:1553	EDC showed the lowest percentage of adhesive-to-dentin failures.					
36744829	3	32	theme	Oral	742:745	arg1	Care					747:750	[3M Oral Care	738:750	RelyX U200 [3M Oral Care	727:750	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	2	33	theme	Ninety	357:362	arg1	canines					379:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines were sectioned, standardizing the length of the roots.					
36744829	8	34	theme	p	1238:1238	arg1	BS					1234:1235	BS	1234:1235	BS (p > 0.05)	1234:1246	For Panavia F 2.0, the treatment did not influence BS (p > 0.05).					
36744829	8	34	theme	p	1238:1238	arg1	>					1240:1240	p > 0.05	1238:1245	p > 0.05	1238:1245	For Panavia F 2.0, the treatment did not influence BS (p > 0.05).					
36744829	12	35	dep	exhibited	1655:1663	arg1	>					1707:1707	p > 0.05	1705:1712	p > 0.05	1705:1712	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	14	36	theme	bond	1899:1902	arg1	strength					1904:1911	higher bond strength	1892:1911	higher bond strength	1892:1911	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	9	37	dep	the	1322:1324	arg1	cements					1326:1332	cements	1326:1332	cements	1326:1332	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	9	38	theme	cervical	1257:1264	arg1	thirds					1277:1282	the cervical and middle thirds	1253:1282	the cervical and middle thirds	1253:1282	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	1	39	dep	PURPOSE	162:168	arg1	evaluate					173:180	evaluate	173:180	To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite	170:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	9	40	theme	middle	1270:1275	arg1	thirds					1277:1282	the cervical and middle thirds	1253:1282	the cervical and middle thirds	1253:1282	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	2	41	theme	maxillary	369:377	arg1	canines					379:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines were sectioned, standardizing the length of the roots.					
36744829	0	42	theme	Chitosan	27:34	arg1	Agents					50:55	Chitosan Cross-linking Agents	27:55	Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite	27:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	3	43	theme	CHI	566:568	arg1	%					576:576	CHI 0.2 wt%	566:576	CHI 0.2 wt%	566:576	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	13	44	theme	dentin	1811:1816	arg1	pre-treatment					1779:1791	pre-treatment	1779:1791	pre-treatment of intraradicular dentin	1779:1816	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	12	45	theme	all	1692:1694	arg1	fluorescence					1676:1687	the lowest fluorescence	1665:1687	the lowest fluorescence of all cements	1665:1702	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	13	46	theme	different	1826:1834	arg1	results					1836:1842	different results	1826:1842	different results	1826:1842	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	7	47	dep	RESULTS	1060:1066	arg1	showed					1078:1083	showed	1078:1083	showed	1078:1083	RESULTS RelyX ARC showed higher BS associated with CHI, while RelyX U200 showed higher BS associated with EDC (p = 0.044).					
36744829	14	48	theme	enzymatic	2035:2043	arg1	activity					2045:2052	lower enzymatic activity	2029:2052	lower enzymatic activity for RelyX ARC	2029:2066	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	11	49	theme	lowest	1506:1511	arg1	percentage					1513:1522	the lowest percentage	1502:1522	the lowest percentage of adhesive-to-dentin failures	1502:1553	EDC showed the lowest percentage of adhesive-to-dentin failures.					
36744829	15	50	theme	EDC	2078:2080	arg1	treatments					2095:2104	EDC and chitosan treatments	2078:2104	EDC and chitosan treatments	2078:2104	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	3	51	theme	wt	574:575	arg1	%					576:576	CHI 0.2 wt%	566:576	CHI 0.2 wt%	566:576	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	15	52	theme	higher	2178:2183	arg1	inhibition					2192:2201	higher enzyme inhibition	2178:2201	higher enzyme inhibition for this composite cement	2178:2227	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	5	53	theme	other	971:975	arg1	half					977:980	the other half	967:980	the other half	967:980	Half of the slices were analyzed immediately, and the other half after 6 months.					
36744829	4	54	theme	in-situ	897:903	arg1	zymography					905:914	in-situ zymography	897:914	in-situ zymography	897:914	Of the slices obtained by sectioning, the most cervical of each third were subjected to a push-out test and the most apical were subjected to in-situ zymography.					
36744829	14	55	theme	bond	2011:2014	arg1	strength					2016:2023	higher bond strength	2004:2023	higher bond strength	2004:2023	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	3	56	theme	EDC	582:584	arg1	0.5M					586:589	EDC 0.5M	582:589	EDC 0.5M	582:589	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	0	57	theme	Different	109:117	arg1	Types					119:123	Different Types	109:123	Different Types of Composite	109:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	10	58	theme	highest	1409:1415	arg1	percentage					1417:1426	The highest percentage	1405:1426	The highest percentage of adhesive-to-dentin failures	1405:1457	The highest percentage of adhesive-to-dentin failures was observed for Panavia F 2.0.					
36744829	12	59	theme	RelyX	1634:1638	arg1	ARC					1640:1642	RelyX ARC	1634:1642	RelyX ARC	1634:1642	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	9	60	theme	higher	1367:1372	arg1	BS					1374:1375	higher BS	1367:1375	higher BS for RelyX U200 (p < 0.001)	1367:1402	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	7	61	theme	higher	1140:1145	arg1	BS					1147:1148	higher BS	1140:1148	higher BS associated with EDC	1140:1168	RESULTS RelyX ARC showed higher BS associated with CHI, while RelyX U200 showed higher BS associated with EDC (p = 0.044).					
36744829	13	62	theme	action	1755:1760	arg1	mechanisms					1741:1750	The different mechanisms	1727:1750	The different mechanisms of action of solutions for pre-treatment of intraradicular dentin	1727:1816	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	13	63	theme	solutions	1765:1773	arg1	action					1755:1760	action	1755:1760	action of solutions for pre-treatment of intraradicular dentin	1755:1816	CONCLUSION The different mechanisms of action of solutions for pre-treatment of intraradicular dentin yielded different results depending on the adhesive used.					
36744829	10	64	theme	failures	1450:1457	arg1	percentage					1417:1426	The highest percentage	1405:1426	The highest percentage of adhesive-to-dentin failures	1405:1457	The highest percentage of adhesive-to-dentin failures was observed for Panavia F 2.0.					
36744829	15	65	theme	bond	2128:2131	arg1	strength					2133:2140	the bond strength	2124:2140	the bond strength for Panavia F 2.0	2124:2158	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	8	66	theme	Panavia	1187:1193	arg1	F					1195:1195	Panavia F 2.0	1187:1199	Panavia F 2.0	1187:1199	For Panavia F 2.0, the treatment did not influence BS (p > 0.05).					
36744829	0	67	theme	Root	149:152	arg1	Dentin					154:159	Root Dentin	149:159	Root Dentin	149:159	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	3	68	dep	RelyX	727:731	arg1	Care					747:750	[3M Oral Care	738:750	RelyX U200 [3M Oral Care	727:750	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	9	69	theme	p	1393:1393	arg1	U200					1387:1390	RelyX U200	1381:1390	RelyX U200 (p < 0.001)	1381:1402	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	9	69	theme	p	1393:1393	arg1	<					1395:1395	p < 0.001	1393:1401	p < 0.001	1393:1401	For the cervical and middle thirds, no differences were observed between the cements, while the apical third revealed higher BS for RelyX U200 (p < 0.001).					
36744829	10	70	theme	Panavia	1476:1482	arg1	F					1484:1484	Panavia F 2.0	1476:1488	Panavia F 2.0	1476:1488	The highest percentage of adhesive-to-dentin failures was observed for Panavia F 2.0.					
36744829	1	71	theme	carbodiimide	196:207	arg1	effect					186:191	the effect	182:191	the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite	182:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	3	72	theme	composite	646:654	arg1	cement					656:661	composite cement	646:661	composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki]	646:721	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	72	theme	composite	646:654	arg1	Care					683:686	RelyX ARC [3M Oral Care	664:686	RelyX ARC [3M Oral Care	664:686	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	1	73	theme	bond	269:272	arg1	strength					274:281	bond strength	269:281	bond strength (BS) of different composite	269:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	73	theme	bond	269:272	arg1	BS					284:285	BS	284:285	BS	284:285	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	15	74	theme	chitosan	2086:2093	arg1	treatments					2095:2104	EDC and chitosan treatments	2078:2104	EDC and chitosan treatments	2078:2104	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	3	75	theme	Oral	678:681	arg1	cement					656:661	composite cement	646:661	composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki]	646:721	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	75	theme	Oral	678:681	arg1	Care					683:686	RelyX ARC [3M Oral Care	664:686	RelyX ARC [3M Oral Care	664:686	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	0	76	theme	Fiberglass	81:90	arg1	Posts					92:96	Fiberglass Posts	81:96	Fiberglass Posts Luted with Different Types of Composite	81:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	3	77	theme	2.0	700:702	arg1	[Kuraray					704:711	[Kuraray	704:711	[Kuraray	704:711	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	78	theme	ARC	670:672	arg1	cement					656:661	composite cement	646:661	composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki]	646:721	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	78	theme	ARC	670:672	arg1	Care					683:686	RelyX ARC [3M Oral Care	664:686	RelyX ARC [3M Oral Care	664:686	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	79	dep	Panavia	690:696	arg1	F					698:698	Panavia F	690:698	Panavia F 2.0 [Kuraray Noritaki	690:720	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	14	80	theme	higher	1917:1922	arg1	inhibition					1931:1940	higher enzyme inhibition	1917:1940	higher enzyme inhibition	1917:1940	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	1	81	theme	different	291:299	arg1	composite					301:309	different composite	291:309	different composite	291:309	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	7	82	theme	RelyX	1068:1072	arg1	ARC					1074:1076	RelyX ARC	1068:1076	RelyX ARC	1068:1076	RESULTS RelyX ARC showed higher BS associated with CHI, while RelyX U200 showed higher BS associated with EDC (p = 0.044).					
36744829	2	83	theme	METHODS	349:355	arg1	canines					379:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines were sectioned, standardizing the length of the roots.					
36744829	3	84	theme	distilled	544:552	arg1	treatment					533:541	dentin treatment	526:541	dentin treatment (distilled water [DW]	526:563	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	3	84	theme	distilled	544:552	arg1	water					554:558	distilled water [DW	544:562	distilled water [DW	544:562	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	14	85	theme	higher	1892:1897	arg1	strength					1904:1911	higher bond strength	1892:1911	higher bond strength	1892:1911	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	2	86	theme	MATERIALS	335:343	arg1	canines					379:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines	335:385	MATERIALS AND METHODS Ninety (90) maxillary canines were sectioned, standardizing the length of the roots.					
36744829	1	87	theme	enzymatic	241:249	arg1	EA					261:262	EA	261:262	EA	261:262	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	1	87	theme	enzymatic	241:249	arg1	activity					251:258	the enzymatic activity	237:258	the enzymatic activity (EA)	237:263	PURPOSE To evaluate the effect of carbodiimide (EDC) and chitosan (CHI) on the enzymatic activity (EA) and bond strength (BS) of different composite cements to root dentin.					
36744829	3	88	theme	[3M	738:740	arg1	Care					747:750	[3M Oral Care	738:750	RelyX U200 [3M Oral Care	727:750	The roots were endodontically treated, prepared, divided into 3 groups according to dentin treatment (distilled water [DW], CHI 0.2 wt%, or EDC 0.5M), and further subdivided into 3 subgroups according to composite cement (RelyX ARC [3M Oral Care], Panavia F 2.0 [Kuraray Noritaki], or RelyX U200 [3M Oral Care]).					
36744829	0	89	theme	Cross-linking	36:48	arg1	Agents					50:55	Chitosan Cross-linking Agents	27:55	Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite	27:136	Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?					
36744829	15	90	theme	composite	2212:2220	arg1	cement					2222:2227	this composite cement	2207:2227	this composite cement	2207:2227	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36744829	5	91	theme	slices	929:934	arg1	Half					917:920	Half	917:920	Half of the slices	917:934	Half of the slices were analyzed immediately, and the other half after 6 months.					
36744829	4	92	theme	push-out	845:852	arg1	test					854:857	a push-out test	843:857	a push-out test	843:857	Of the slices obtained by sectioning, the most cervical of each third were subjected to a push-out test and the most apical were subjected to in-situ zymography.					
36744829	14	93	theme	RelyX	2058:2062	arg1	ARC					2064:2066	RelyX ARC	2058:2066	RelyX ARC	2058:2066	EDC resulted in higher bond strength and higher enzyme inhibition for RelyX U200, while the treatment with chitosan resulted in higher bond strength and lower enzymatic activity for RelyX ARC.					
36744829	12	94	theme	lowest	1669:1674	arg1	fluorescence					1676:1687	the lowest fluorescence	1665:1687	the lowest fluorescence of all cements	1665:1702	According to zymographic analysis, DW and CHI showed greater fluorescence for RelyX ARC, while EDC exhibited the lowest fluorescence of all cements (p > 0.05).					
36744829	11	95	theme	adhesive-to-dentin	1527:1544	arg1	failures					1546:1553	adhesive-to-dentin failures	1527:1553	adhesive-to-dentin failures	1527:1553	EDC showed the lowest percentage of adhesive-to-dentin failures.					
36744829	15	96	theme	enzyme	2185:2190	arg1	inhibition					2192:2201	higher enzyme inhibition	2178:2201	higher enzyme inhibition for this composite cement	2178:2227	Although EDC and chitosan treatments did not influence the bond strength for Panavia F 2.0, both resulted in higher enzyme inhibition for this composite cement.					
36007701	5	0	theme	loading	742:748	arg1	1767 mg/g					760:768	1767 mg/g	760:768	1767 mg/g	760:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	5	0	theme	loading	742:748	arg1	amount					750:755	high drug loading amount	732:755	high drug loading amount of 1767 mg/g	732:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	6	1	dep	biocompatibility	834:849	arg1	non-cytotoxicity					885:900	non-cytotoxicity	885:900	non-cytotoxicity	885:900	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	6	1	dep	biocompatibility	834:849	arg1	non-irritant					852:863	non-irritant	852:863	non-irritant	852:863	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	6	1	dep	biocompatibility	834:849	arg1	non-hemolysis					866:878	non-hemolysis	866:878	non-hemolysis	866:878	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	1	2	theme	due	151:153	arg1	nanocarrier					139:149	a noticeable drug nanocarrier	121:149	a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity	121:203	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	6	3	theme	disease	1015:1021	arg1	scores					1038:1043	the disease activity index scores	1011:1043	the disease activity index scores	1011:1043	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	3	4	theme	Various	333:339	arg1	drugs					351:355	Various insoluble drugs	333:355	Various insoluble drugs	333:355	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	4	5	theme	natural	499:505	arg1	polyphenol					507:516	a natural polyphenol	497:516	a natural polyphenol with initial antioxidant and anti-inflammatory effects	497:571	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	4	5	theme	natural	499:505	arg1	proanthocyanidins					472:488	proanthocyanidins	472:488	proanthocyanidins (PAC)	472:494	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	6	6	theme	antioxidant	797:807	arg1	efficiency					809:818	high antioxidant efficiency	792:818	high antioxidant efficiency	792:818	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	6	7	theme	oxidative	1100:1108	arg1	stress					1110:1115	oxidative stress	1100:1115	oxidative stress	1100:1115	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	8	theme	~136 nm	712:718	arg1	diameter					700:707	an average particle diameter	680:707	an average particle diameter of ~136 nm	680:718	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	7	9	dep	provides	1200:1207	arg1	promises					1269:1276	promises	1269:1276	promises high potential in therapeutic and pharmaceutical applications	1269:1338	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	6	10	theme	high	792:795	arg1	efficiency					809:818	high antioxidant efficiency	792:818	high antioxidant efficiency	792:818	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	7	11	theme	SS-stabilized-drug	1238:1255	arg1	composites					1257:1266	SS-stabilized-drug composites	1238:1266	SS-stabilized-drug composites	1238:1266	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	6	12	theme	colitis	989:995	arg1	symptoms					935:942	the symptoms	931:942	the symptoms of dextran sulfate sodium-induced ulcerative colitis	931:995	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	0	13	theme	Silk	0:3	arg1	sericin					5:11	Silk sericin	0:11	Silk sericin	0:11	Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis.					
36007701	7	14	theme	pharmaceutical	1312:1325	arg1	applications					1327:1338	therapeutic and pharmaceutical applications	1296:1338	therapeutic and pharmaceutical applications	1296:1338	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	7	15	theme	simple	1211:1216	arg1	method					1218:1223	a simple method	1209:1223	a simple method to fabricate SS-stabilized-drug composites	1209:1266	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	6	16	theme	length	1081:1086	arg1	shortening					1061:1070	the shortening	1057:1070	the shortening of colon length	1057:1086	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	1	17	theme	Silk	92:95	arg1	SS					106:107	SS	106:107	SS	106:107	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	1	17	theme	Silk	92:95	arg1	sericin					97:103	Silk sericin	92:103	Silk sericin (SS)	92:108	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	1	18	theme	excellent	162:170	arg1	biocompatibility					172:187	its excellent biocompatibility	158:187	its excellent biocompatibility	158:187	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	3	19	theme	high	390:393	arg1	amount					403:408	high loading amount	390:408	high loading amount	390:408	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	0	20	theme	colitis	83:89	arg1	alleviation					57:67	synergetic alleviation	46:67	synergetic alleviation of ulcerative colitis	46:89	Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis.					
36007701	3	21	with	SS	382:383	arg1	amount					403:408	high loading amount	390:408	high loading amount	390:408	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	3	22	theme	good	422:425	arg1	dispersity					427:436	good dispersity	422:436	good dispersity	422:436	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	3	23	theme	loading	395:401	arg1	amount					403:408	high loading amount	390:408	high loading amount	390:408	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	4	24	theme	anti-inflammatory	547:563	arg1	effects					565:571	initial antioxidant and anti-inflammatory effects	523:571	initial antioxidant and anti-inflammatory effects	523:571	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	2	25	theme	SS-stabilized-drug	302:319	arg1	composites					321:330	SS-stabilized-drug composites	302:330	SS-stabilized-drug composites	302:330	To further extend the application of SS, a facile one-step process was constructed to fabricate SS-stabilized-drug composites.					
36007701	6	26	dep	exhibited	782:790	arg1	alleviate					921:929	alleviate	921:929	could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries	904:1187	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	27	with	solution	666:673	arg1	diameter					700:707	an average particle diameter	680:707	an average particle diameter of ~136 nm	680:718	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	6	28	theme	ulcerative	978:987	arg1	colitis					989:995	dextran sulfate sodium-induced ulcerative colitis	947:995	dextran sulfate sodium-induced ulcerative colitis	947:995	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	29	theme	average	683:689	arg1	diameter					700:707	an average particle diameter	680:707	an average particle diameter of ~136 nm	680:718	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	6	30	theme	histopathological	1162:1178	arg1	injuries					1180:1187	the histopathological injuries	1158:1187	the histopathological injuries	1158:1187	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	6	31	theme	sodium-induced	963:976	arg1	colitis					989:995	dextran sulfate sodium-induced ulcerative colitis	947:995	dextran sulfate sodium-induced ulcerative colitis	947:995	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	32	theme	particle	691:698	arg1	diameter					700:707	an average particle diameter	680:707	an average particle diameter of ~136 nm	680:718	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	4	33	with	polyphenol	507:516	arg1	effects					565:571	initial antioxidant and anti-inflammatory effects	523:571	initial antioxidant and anti-inflammatory effects	523:571	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	0	34	theme	synergetic	46:55	arg1	alleviation					57:67	synergetic alleviation	46:67	synergetic alleviation of ulcerative colitis	46:89	Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis.					
36007701	6	35	theme	sulfate	955:961	arg1	colitis					989:995	dextran sulfate sodium-induced ulcerative colitis	947:995	dextran sulfate sodium-induced ulcerative colitis	947:995	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	36	theme	high	732:735	arg1	1767 mg/g					760:768	1767 mg/g	760:768	1767 mg/g	760:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	5	36	theme	high	732:735	arg1	amount					750:755	high drug loading amount	732:755	high drug loading amount of 1767 mg/g	732:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	6	37	theme	colon	1075:1079	arg1	length					1081:1086	colon length	1075:1086	colon length	1075:1086	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	38	theme	1767 mg/g	760:768	arg1	1767 mg/g					760:768	1767 mg/g	760:768	1767 mg/g	760:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	5	38	theme	1767 mg/g	760:768	arg1	amount					750:755	high drug loading amount	732:755	high drug loading amount of 1767 mg/g	732:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	6	39	theme	dextran	947:953	arg1	sulfate					955:961	dextran sulfate	947:961	dextran sulfate sodium-induced ulcerative colitis	947:995	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	6	40	theme	index	1032:1036	arg1	scores					1038:1043	the disease activity index scores	1011:1043	the disease activity index scores	1011:1043	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	5	41	theme	aqueous	658:664	arg1	solution					666:673	aqueous solution	658:673	aqueous solution with an average particle diameter of ~136 nm	658:718	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	5	42	theme	drug	737:740	arg1	1767 mg/g					760:768	1767 mg/g	760:768	1767 mg/g	760:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	5	42	theme	drug	737:740	arg1	amount					750:755	high drug loading amount	732:755	high drug loading amount of 1767 mg/g	732:768	The SS/PAC can disperse uniformly in aqueous solution with an average particle diameter of ~136 nm, and showed high drug loading amount of 1767 mg/g.					
36007701	4	43	theme	antioxidant	531:541	arg1	effects					565:571	initial antioxidant and anti-inflammatory effects	523:571	initial antioxidant and anti-inflammatory effects	523:571	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	4	44	theme	initial	523:529	arg1	effects					565:571	initial antioxidant and anti-inflammatory effects	523:571	initial antioxidant and anti-inflammatory effects	523:571	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	6	45	theme	excellent	824:832	arg1	biocompatibility					834:849	excellent biocompatibility	824:849	excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity)	824:901	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.					
36007701	2	46	theme	facile	249:254	arg1	process					265:271	a facile one-step process	247:271	a facile one-step process	247:271	To further extend the application of SS, a facile one-step process was constructed to fabricate SS-stabilized-drug composites.					
36007701	7	47	from	potential	1283:1291	arg1	applications					1327:1338	therapeutic and pharmaceutical applications	1296:1338	therapeutic and pharmaceutical applications	1296:1338	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	2	48	theme	one-step	256:263	arg1	process					265:271	a facile one-step process	247:271	a facile one-step process	247:271	To further extend the application of SS, a facile one-step process was constructed to fabricate SS-stabilized-drug composites.					
36007701	1	49	theme	noticeable	123:132	arg1	nanocarrier					139:149	a noticeable drug nanocarrier	121:149	a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity	121:203	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	3	50	theme	insoluble	341:349	arg1	drugs					351:355	Various insoluble drugs	333:355	Various insoluble drugs	333:355	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	1	51	theme	drug	134:137	arg1	nanocarrier					139:149	a noticeable drug nanocarrier	121:149	a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity	121:203	Silk sericin (SS) has become a noticeable drug nanocarrier due to its excellent biocompatibility and bioactivity.					
36007701	3	52	theme	aqueous	441:447	arg1	solution					449:456	aqueous solution	441:456	aqueous solution	441:456	Various insoluble drugs can be encapsulated into SS with high loading amount, and showed good dispersity in aqueous solution.					
36007701	4	53	theme	SS/PAC	602:607	arg1	composites					609:618	SS/PAC composites	602:618	SS/PAC composites	602:618	For example, proanthocyanidins (PAC), a natural polyphenol with initial antioxidant and anti-inflammatory effects, can be loaded on SS to form SS/PAC composites.					
36007701	0	54	theme	ulcerative	72:81	arg1	colitis					83:89	ulcerative colitis	72:89	ulcerative colitis	72:89	Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis.					
36007701	2	55	theme	SS	243:244	arg1	application					228:238	the application	224:238	the application of SS	224:244	To further extend the application of SS, a facile one-step process was constructed to fabricate SS-stabilized-drug composites.					
36007701	7	56	theme	therapeutic	1296:1306	arg1	applications					1327:1338	therapeutic and pharmaceutical applications	1296:1338	therapeutic and pharmaceutical applications	1296:1338	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	7	57	theme	high	1278:1281	arg1	potential					1283:1291	high potential	1278:1291	high potential in therapeutic and pharmaceutical applications	1278:1338	This work provides a simple method to fabricate SS-stabilized-drug composites, promises high potential in therapeutic and pharmaceutical applications.					
36007701	6	58	theme	activity	1023:1030	arg1	scores					1038:1043	the disease activity index scores	1011:1043	the disease activity index scores	1011:1043	The SS/PAC exhibited high antioxidant efficiency and excellent biocompatibility (non-irritant, non-hemolysis, and non-cytotoxicity), could remarkably alleviate the symptoms of dextran sulfate sodium-induced ulcerative colitis by decreasing the disease activity index scores, inhibiting the shortening of colon length, regulating oxidative stress, suppressing inflammation, and reversing the histopathological injuries.